CAK77_RS21250 f06922bc899790db9f8c8fce4b764a5c 982 SUPERFAMILY SSF82866 753 979 3.14E-27 T 06-07-2017 CAK77_RS21250 f06922bc899790db9f8c8fce4b764a5c 982 Gene3D G3DSA:1.20.1640.10 164 346 9.0E-26 T 06-07-2017 CAK77_RS21250 f06922bc899790db9f8c8fce4b764a5c 982 Gene3D G3DSA:1.20.1640.10 767 981 1.1E-22 T 06-07-2017 CAK77_RS21250 f06922bc899790db9f8c8fce4b764a5c 982 SUPERFAMILY SSF82866 161 345 1.83E-25 T 06-07-2017 CAK77_RS21250 f06922bc899790db9f8c8fce4b764a5c 982 Pfam PF03176 MMPL family 45 372 4.4E-69 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 CAK77_RS21250 f06922bc899790db9f8c8fce4b764a5c 982 Pfam PF03176 MMPL family 657 980 5.2E-73 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 CAK77_RS09995 734705e1bfc4a1842af30f3927f25ba3 156 Gene3D G3DSA:3.10.129.10 9 147 1.8E-18 T 06-07-2017 IPR029069 HotDog domain CAK77_RS09995 734705e1bfc4a1842af30f3927f25ba3 156 Pfam PF01575 MaoC like domain 27 120 5.6E-5 T 06-07-2017 IPR002539 MaoC-like domain CAK77_RS09995 734705e1bfc4a1842af30f3927f25ba3 156 SUPERFAMILY SSF54637 12 146 5.86E-20 T 06-07-2017 IPR029069 HotDog domain CAK77_RS09280 dbbc2ce208acaeb09fa8ef15f829f875 600 SUPERFAMILY SSF56801 386 593 2.49E-102 T 06-07-2017 CAK77_RS09280 dbbc2ce208acaeb09fa8ef15f829f875 600 SUPERFAMILY SSF56801 22 359 2.49E-102 T 06-07-2017 CAK77_RS09280 dbbc2ce208acaeb09fa8ef15f829f875 600 Gene3D G3DSA:3.40.50.980 192 358 7.9E-26 T 06-07-2017 CAK77_RS09280 dbbc2ce208acaeb09fa8ef15f829f875 600 Gene3D G3DSA:2.30.38.10 388 480 2.0E-18 T 06-07-2017 CAK77_RS09280 dbbc2ce208acaeb09fa8ef15f829f875 600 Pfam PF00501 AMP-binding enzyme 29 489 6.2E-74 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK77_RS09280 dbbc2ce208acaeb09fa8ef15f829f875 600 Gene3D G3DSA:3.30.300.30 481 590 2.1E-16 T 06-07-2017 CAK77_RS09280 dbbc2ce208acaeb09fa8ef15f829f875 600 Gene3D G3DSA:3.40.50.980 23 191 4.7E-27 T 06-07-2017 CAK77_RS01840 cc71eb0d2c2da8c666323ff5dd939f4d 464 SUPERFAMILY SSF103473 9 452 2.35E-63 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK77_RS01840 cc71eb0d2c2da8c666323ff5dd939f4d 464 Pfam PF00083 Sugar (and other) transporter 17 455 6.1E-91 T 06-07-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CAK77_RS01840 cc71eb0d2c2da8c666323ff5dd939f4d 464 ProSitePatterns PS00217 Sugar transport proteins signature 2. 113 138 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CAK77_RS01840 cc71eb0d2c2da8c666323ff5dd939f4d 464 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 3 451 8.4E-87 T 06-07-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CAK77_RS01840 cc71eb0d2c2da8c666323ff5dd939f4d 464 PRINTS PR00171 Sugar transporter signature 108 127 1.3E-15 T 06-07-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CAK77_RS01840 cc71eb0d2c2da8c666323ff5dd939f4d 464 PRINTS PR00171 Sugar transporter signature 356 377 1.3E-15 T 06-07-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CAK77_RS01840 cc71eb0d2c2da8c666323ff5dd939f4d 464 PRINTS PR00171 Sugar transporter signature 379 391 1.3E-15 T 06-07-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CAK77_RS01840 cc71eb0d2c2da8c666323ff5dd939f4d 464 PRINTS PR00171 Sugar transporter signature 25 35 1.3E-15 T 06-07-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CAK77_RS01840 cc71eb0d2c2da8c666323ff5dd939f4d 464 PRINTS PR00171 Sugar transporter signature 264 274 1.3E-15 T 06-07-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CAK77_RS01840 cc71eb0d2c2da8c666323ff5dd939f4d 464 Gene3D G3DSA:1.20.1250.20 22 196 4.2E-25 T 06-07-2017 CAK77_RS01840 cc71eb0d2c2da8c666323ff5dd939f4d 464 Gene3D G3DSA:1.20.1250.20 244 450 3.1E-17 T 06-07-2017 CAK77_RS03295 e800568e573ff1a9c7e916f0cbe50bb5 728 Gene3D G3DSA:2.40.40.20 15 88 1.8E-9 T 06-07-2017 CAK77_RS03295 e800568e573ff1a9c7e916f0cbe50bb5 728 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 254 372 2.8E-13 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 CAK77_RS03295 e800568e573ff1a9c7e916f0cbe50bb5 728 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 505 635 4.5E-39 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 CAK77_RS03295 e800568e573ff1a9c7e916f0cbe50bb5 728 SUPERFAMILY SSF50692 16 87 1.1E-9 T 06-07-2017 IPR009010 Aspartate decarboxylase-like domain CAK77_RS03295 e800568e573ff1a9c7e916f0cbe50bb5 728 Gene3D G3DSA:3.40.50.300 216 382 5.6E-24 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS03295 e800568e573ff1a9c7e916f0cbe50bb5 728 Gene3D G3DSA:3.40.50.300 465 645 4.1E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS03295 e800568e573ff1a9c7e916f0cbe50bb5 728 ProSitePatterns PS00674 AAA-protein family signature. 606 624 - T 06-07-2017 IPR003960 ATPase, AAA-type, conserved site GO:0005524 CAK77_RS03295 e800568e573ff1a9c7e916f0cbe50bb5 728 SMART SM00382 501 638 5.0E-18 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS03295 e800568e573ff1a9c7e916f0cbe50bb5 728 SMART SM00382 250 372 9.0E-6 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS03295 e800568e573ff1a9c7e916f0cbe50bb5 728 SMART SM01073 5 89 1.4E-16 T 06-07-2017 IPR003338 CDC48, N-terminal subdomain CAK77_RS03295 e800568e573ff1a9c7e916f0cbe50bb5 728 Gene3D G3DSA:1.10.8.60 646 714 2.6E-19 T 06-07-2017 CAK77_RS03295 e800568e573ff1a9c7e916f0cbe50bb5 728 SUPERFAMILY SSF52540 464 711 1.66E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS03295 e800568e573ff1a9c7e916f0cbe50bb5 728 Pfam PF02359 Cell division protein 48 (CDC48), N-terminal domain 16 88 2.8E-12 T 06-07-2017 IPR003338 CDC48, N-terminal subdomain CAK77_RS03295 e800568e573ff1a9c7e916f0cbe50bb5 728 Gene3D G3DSA:1.10.8.60 383 451 3.8E-14 T 06-07-2017 CAK77_RS03295 e800568e573ff1a9c7e916f0cbe50bb5 728 SUPERFAMILY SSF52540 216 448 1.6E-28 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS03295 e800568e573ff1a9c7e916f0cbe50bb5 728 SMART SM01072 103 188 8.1E-4 T 06-07-2017 IPR004201 CDC48, domain 2 CAK77_RS09435 980d43cfdc7d644160b4d7f820b4927b 230 Hamap MF_00013 Octanoyltransferase [lipB]. 17 223 31.978 T 06-07-2017 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CAK77_RS09435 980d43cfdc7d644160b4d7f820b4927b 230 ProSitePatterns PS01313 Lipoate-protein ligase B signature. 82 97 - T 06-07-2017 IPR020605 Octanoyltransferase, conserved site GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 CAK77_RS09435 980d43cfdc7d644160b4d7f820b4927b 230 Pfam PF03099 Biotin/lipoate A/B protein ligase family 75 173 1.6E-9 T 06-07-2017 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 CAK77_RS09435 980d43cfdc7d644160b4d7f820b4927b 230 TIGRFAM TIGR00214 lipB: lipoyl(octanoyl) transferase 48 219 3.6E-36 T 06-07-2017 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CAK77_RS09435 980d43cfdc7d644160b4d7f820b4927b 230 SUPERFAMILY SSF55681 15 222 4.39E-65 T 06-07-2017 CAK77_RS09435 980d43cfdc7d644160b4d7f820b4927b 230 Gene3D G3DSA:3.90.1550.10 17 220 8.7E-74 T 06-07-2017 CAK77_RS09435 980d43cfdc7d644160b4d7f820b4927b 230 ProDom PD006086 LIGASE LIPOATE-PROTEIN B TRANSFERASE ACYLTRANSFERASE LIPOYLTRANSFERASE LIPOYL-ACYL-CARRIER 2.3.1.- PROTEIN-PROTEIN- N-LIPOYLTRANSFERASE 86 138 8.0E-19 T 06-07-2017 CAK77_RS09435 980d43cfdc7d644160b4d7f820b4927b 230 PIRSF PIRSF016262 14 226 1.2E-60 T 06-07-2017 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CAK77_RS10690 3bc993a1fa5da98d3364d44fbc03ca2a 421 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 28 206 5.0E-15 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAK77_RS10690 3bc993a1fa5da98d3364d44fbc03ca2a 421 TIGRFAM TIGR02467 CbiE: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit 31 209 4.3E-35 T 06-07-2017 IPR012818 Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase GO:0008276|GO:0009236 CAK77_RS10690 3bc993a1fa5da98d3364d44fbc03ca2a 421 Gene3D G3DSA:3.40.1010.10 27 132 3.8E-21 T 06-07-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAK77_RS10690 3bc993a1fa5da98d3364d44fbc03ca2a 421 TIGRFAM TIGR02469 CbiT: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit 253 372 6.8E-30 T 06-07-2017 IPR014008 Cobalamin biosynthesis, precorrin-6Y methyltransferase, CbiT subunit GO:0008276|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.196|MetaCyc: PWY-2201|MetaCyc: PWY-7377 CAK77_RS10690 3bc993a1fa5da98d3364d44fbc03ca2a 421 Gene3D G3DSA:3.40.50.150 253 420 4.7E-18 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS10690 3bc993a1fa5da98d3364d44fbc03ca2a 421 Gene3D G3DSA:3.30.950.10 133 228 2.2E-15 T 06-07-2017 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAK77_RS10690 3bc993a1fa5da98d3364d44fbc03ca2a 421 SUPERFAMILY SSF53335 227 416 3.31E-25 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS10690 3bc993a1fa5da98d3364d44fbc03ca2a 421 PIRSF PIRSF036428 24 421 6.4E-123 T 06-07-2017 IPR006365 Cobalamin (vitamin B12) biosynthesis CobL/Precorrin-6Y C(5,15)-methyltransferase GO:0008276|GO:0009236 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|KEGG: 00860+2.1.1.132|MetaCyc: PWY-2201|MetaCyc: PWY-3841 CAK77_RS10690 3bc993a1fa5da98d3364d44fbc03ca2a 421 SUPERFAMILY SSF53790 29 227 2.49E-29 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAK77_RS11820 004caf41a5ad58d2851924f0030d480f 266 TIGRFAM TIGR01581 Mo_ABC_porter: NifC-like ABC-type porter 29 251 2.2E-76 T 06-07-2017 IPR006469 NifC-like ABC-type porter GO:0005215|GO:0006810|GO:0016020 CAK77_RS11820 004caf41a5ad58d2851924f0030d480f 266 Gene3D G3DSA:1.10.3720.10 10 251 6.7E-42 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS11820 004caf41a5ad58d2851924f0030d480f 266 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 69 250 4.1E-18 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS11820 004caf41a5ad58d2851924f0030d480f 266 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 53 255 1.4E-62 T 06-07-2017 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 CAK77_RS11820 004caf41a5ad58d2851924f0030d480f 266 SUPERFAMILY SSF161098 9 252 1.57E-47 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS05555 ea55e31e10fb2e4c464be67ff9c6037b 404 SUPERFAMILY SSF55909 7 402 9.81E-118 T 06-07-2017 CAK77_RS05555 ea55e31e10fb2e4c464be67ff9c6037b 404 PIRSF PIRSF006356 3 404 3.0E-136 T 06-07-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CAK77_RS05555 ea55e31e10fb2e4c464be67ff9c6037b 404 TIGRFAM TIGR01078 arcA: arginine deiminase 10 402 5.5E-150 T 06-07-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CAK77_RS05555 ea55e31e10fb2e4c464be67ff9c6037b 404 Pfam PF02274 Amidinotransferase 21 401 3.1E-91 T 06-07-2017 CAK77_RS05555 ea55e31e10fb2e4c464be67ff9c6037b 404 Gene3D G3DSA:3.75.10.10 7 70 9.6E-117 T 06-07-2017 CAK77_RS05555 ea55e31e10fb2e4c464be67ff9c6037b 404 Gene3D G3DSA:3.75.10.10 156 402 9.6E-117 T 06-07-2017 CAK77_RS05555 ea55e31e10fb2e4c464be67ff9c6037b 404 Hamap MF_00242 Arginine deiminase [arcA]. 4 404 42.16 T 06-07-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CAK77_RS05555 ea55e31e10fb2e4c464be67ff9c6037b 404 PRINTS PR01466 Bacterial arginine deiminase signature 5 25 5.0E-47 T 06-07-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CAK77_RS05555 ea55e31e10fb2e4c464be67ff9c6037b 404 PRINTS PR01466 Bacterial arginine deiminase signature 156 174 5.0E-47 T 06-07-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CAK77_RS05555 ea55e31e10fb2e4c464be67ff9c6037b 404 PRINTS PR01466 Bacterial arginine deiminase signature 184 199 5.0E-47 T 06-07-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CAK77_RS05555 ea55e31e10fb2e4c464be67ff9c6037b 404 PRINTS PR01466 Bacterial arginine deiminase signature 383 401 5.0E-47 T 06-07-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CAK77_RS05555 ea55e31e10fb2e4c464be67ff9c6037b 404 PRINTS PR01466 Bacterial arginine deiminase signature 360 374 5.0E-47 T 06-07-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CAK77_RS05555 ea55e31e10fb2e4c464be67ff9c6037b 404 PRINTS PR01466 Bacterial arginine deiminase signature 340 357 5.0E-47 T 06-07-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CAK77_RS16865 7f15209f00cea722bf3cd29d2acc5db9 92 Gene3D G3DSA:3.30.70.1060 15 76 1.2E-9 T 06-07-2017 CAK77_RS16865 7f15209f00cea722bf3cd29d2acc5db9 92 Pfam PF03795 YCII-related domain 7 76 1.1E-8 T 06-07-2017 IPR005545 YCII-related CAK77_RS16865 7f15209f00cea722bf3cd29d2acc5db9 92 SUPERFAMILY SSF54909 1 82 2.06E-13 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAK77_RS00390 5c6a3eb3c10e508e5e8c84cddfe49e32 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 10 56 1.8E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS00390 5c6a3eb3c10e508e5e8c84cddfe49e32 195 SUPERFAMILY SSF46689 2 74 2.98E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS00390 5c6a3eb3c10e508e5e8c84cddfe49e32 195 Gene3D G3DSA:1.10.357.10 2 184 1.9E-29 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS12515 3df4ebe473f06f612cff3e632af30ff3 291 SUPERFAMILY SSF52402 10 151 1.59E-27 T 06-07-2017 CAK77_RS12515 3df4ebe473f06f612cff3e632af30ff3 291 Gene3D G3DSA:3.40.50.620 10 150 3.4E-31 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS12515 3df4ebe473f06f612cff3e632af30ff3 291 Gene3D G3DSA:3.40.50.620 156 289 1.0E-34 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS12515 3df4ebe473f06f612cff3e632af30ff3 291 Pfam PF00582 Universal stress protein family 10 148 1.5E-20 T 06-07-2017 IPR006016 UspA GO:0006950 CAK77_RS12515 3df4ebe473f06f612cff3e632af30ff3 291 Pfam PF00582 Universal stress protein family 158 289 1.6E-25 T 06-07-2017 IPR006016 UspA GO:0006950 CAK77_RS12515 3df4ebe473f06f612cff3e632af30ff3 291 SUPERFAMILY SSF52402 157 290 7.03E-32 T 06-07-2017 CAK77_RS12515 3df4ebe473f06f612cff3e632af30ff3 291 PRINTS PR01438 Universal stress protein signature 249 261 7.4E-19 T 06-07-2017 IPR006015 Universal stress protein A CAK77_RS12515 3df4ebe473f06f612cff3e632af30ff3 291 PRINTS PR01438 Universal stress protein signature 267 289 7.4E-19 T 06-07-2017 IPR006015 Universal stress protein A CAK77_RS12515 3df4ebe473f06f612cff3e632af30ff3 291 PRINTS PR01438 Universal stress protein signature 156 174 7.4E-19 T 06-07-2017 IPR006015 Universal stress protein A CAK77_RS17460 cd324666f68af8732be5d8ed17e1a04a 470 SUPERFAMILY SSF56645 104 327 2.75E-47 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK77_RS17460 cd324666f68af8732be5d8ed17e1a04a 470 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 110 219 1.4E-21 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS17460 cd324666f68af8732be5d8ed17e1a04a 470 SUPERFAMILY SSF47203 339 467 9.83E-34 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS17460 cd324666f68af8732be5d8ed17e1a04a 470 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 438 457 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CAK77_RS17460 cd324666f68af8732be5d8ed17e1a04a 470 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 339 466 8.5E-25 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS17460 cd324666f68af8732be5d8ed17e1a04a 470 Gene3D G3DSA:2.40.110.10 228 318 2.7E-21 T 06-07-2017 CAK77_RS17460 cd324666f68af8732be5d8ed17e1a04a 470 Gene3D G3DSA:1.10.540.10 100 219 5.7E-25 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS17460 cd324666f68af8732be5d8ed17e1a04a 470 Gene3D G3DSA:1.20.140.10 319 466 2.5E-39 T 06-07-2017 CAK77_RS17460 cd324666f68af8732be5d8ed17e1a04a 470 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 228 316 5.2E-13 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAK77_RS04080 1666e0475dcf6bf3f53b89e7a5703ac6 297 Gene3D G3DSA:1.10.1040.10 174 223 3.5E-8 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAK77_RS04080 1666e0475dcf6bf3f53b89e7a5703ac6 297 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 169 194 - T 06-07-2017 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 CAK77_RS04080 1666e0475dcf6bf3f53b89e7a5703ac6 297 SUPERFAMILY SSF51735 5 169 3.61E-39 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS04080 1666e0475dcf6bf3f53b89e7a5703ac6 297 SUPERFAMILY SSF48179 172 243 8.5E-10 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAK77_RS04080 1666e0475dcf6bf3f53b89e7a5703ac6 297 Gene3D G3DSA:3.40.50.720 4 173 1.2E-40 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS04080 1666e0475dcf6bf3f53b89e7a5703ac6 297 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 172 240 5.0E-13 T 06-07-2017 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 CAK77_RS04080 1666e0475dcf6bf3f53b89e7a5703ac6 297 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 8 168 3.9E-36 T 06-07-2017 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 CAK77_RS11495 cdeca5cd683a3d30868661b82664ac99 586 SUPERFAMILY SSF52540 1 226 5.26E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS11495 cdeca5cd683a3d30868661b82664ac99 586 SUPERFAMILY SSF52540 5 50 4.59E-19 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS11495 cdeca5cd683a3d30868661b82664ac99 586 SUPERFAMILY SSF52540 405 536 4.59E-19 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS11495 cdeca5cd683a3d30868661b82664ac99 586 Gene3D G3DSA:3.40.50.300 2 215 5.2E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS11495 cdeca5cd683a3d30868661b82664ac99 586 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 580 2.5E-196 T 06-07-2017 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 CAK77_RS11495 cdeca5cd683a3d30868661b82664ac99 586 Pfam PF02463 RecF/RecN/SMC N terminal domain 4 537 1.9E-16 T 06-07-2017 IPR003395 RecF/RecN/SMC, N-terminal CAK77_RS11495 cdeca5cd683a3d30868661b82664ac99 586 PIRSF PIRSF003128 1 584 7.4E-163 T 06-07-2017 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 CAK77_RS11495 cdeca5cd683a3d30868661b82664ac99 586 Gene3D G3DSA:3.40.50.300 459 536 1.1E-6 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS04340 4d46be20a97cea62a2104f811eb7c2f3 222 Gene3D G3DSA:1.10.357.10 64 208 1.6E-37 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS04340 4d46be20a97cea62a2104f811eb7c2f3 222 SUPERFAMILY SSF46689 4 64 8.21E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS04340 4d46be20a97cea62a2104f811eb7c2f3 222 Gene3D G3DSA:1.10.10.60 3 61 3.8E-20 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS04340 4d46be20a97cea62a2104f811eb7c2f3 222 SUPERFAMILY SSF48498 68 210 5.0E-30 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS04340 4d46be20a97cea62a2104f811eb7c2f3 222 Pfam PF00440 Bacterial regulatory proteins, tetR family 10 52 5.0E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS04340 4d46be20a97cea62a2104f811eb7c2f3 222 PRINTS PR00400 Tetracycline repressor protein signature 20 43 9.0E-18 T 06-07-2017 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 CAK77_RS04340 4d46be20a97cea62a2104f811eb7c2f3 222 PRINTS PR00400 Tetracycline repressor protein signature 73 92 9.0E-18 T 06-07-2017 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 CAK77_RS04340 4d46be20a97cea62a2104f811eb7c2f3 222 PRINTS PR00400 Tetracycline repressor protein signature 127 146 9.0E-18 T 06-07-2017 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 CAK77_RS04340 4d46be20a97cea62a2104f811eb7c2f3 222 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 70 206 1.9E-27 T 06-07-2017 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 CAK77_RS04340 4d46be20a97cea62a2104f811eb7c2f3 222 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 52 3.2E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS04340 4d46be20a97cea62a2104f811eb7c2f3 222 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 8 21 3.2E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS18970 5f8ab3b0d2ff1eaca52456a79c463283 179 SUPERFAMILY SSF69318 64 128 2.35E-6 T 06-07-2017 CAK77_RS18970 5f8ab3b0d2ff1eaca52456a79c463283 179 Gene3D G3DSA:2.130.10.130 63 114 1.0E-5 T 06-07-2017 CAK77_RS12875 c82f39ebd2bf06c1d6bba79ec6395801 564 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 39 482 7.9E-149 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK77_RS12875 c82f39ebd2bf06c1d6bba79ec6395801 564 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 31 535 5.2E-217 T 06-07-2017 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005507|GO:0005886|GO:0006810|GO:0022900|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 CAK77_RS12875 c82f39ebd2bf06c1d6bba79ec6395801 564 PRINTS PR01165 Cytochrome c oxidase subunit I signature 325 346 1.6E-101 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK77_RS12875 c82f39ebd2bf06c1d6bba79ec6395801 564 PRINTS PR01165 Cytochrome c oxidase subunit I signature 257 278 1.6E-101 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK77_RS12875 c82f39ebd2bf06c1d6bba79ec6395801 564 PRINTS PR01165 Cytochrome c oxidase subunit I signature 236 257 1.6E-101 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK77_RS12875 c82f39ebd2bf06c1d6bba79ec6395801 564 PRINTS PR01165 Cytochrome c oxidase subunit I signature 146 158 1.6E-101 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK77_RS12875 c82f39ebd2bf06c1d6bba79ec6395801 564 PRINTS PR01165 Cytochrome c oxidase subunit I signature 360 378 1.6E-101 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK77_RS12875 c82f39ebd2bf06c1d6bba79ec6395801 564 PRINTS PR01165 Cytochrome c oxidase subunit I signature 207 226 1.6E-101 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK77_RS12875 c82f39ebd2bf06c1d6bba79ec6395801 564 PRINTS PR01165 Cytochrome c oxidase subunit I signature 29 54 1.6E-101 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK77_RS12875 c82f39ebd2bf06c1d6bba79ec6395801 564 PRINTS PR01165 Cytochrome c oxidase subunit I signature 76 99 1.6E-101 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK77_RS12875 c82f39ebd2bf06c1d6bba79ec6395801 564 PRINTS PR01165 Cytochrome c oxidase subunit I signature 178 196 1.6E-101 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK77_RS12875 c82f39ebd2bf06c1d6bba79ec6395801 564 PRINTS PR01165 Cytochrome c oxidase subunit I signature 303 318 1.6E-101 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK77_RS12875 c82f39ebd2bf06c1d6bba79ec6395801 564 PRINTS PR01165 Cytochrome c oxidase subunit I signature 103 127 1.6E-101 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK77_RS12875 c82f39ebd2bf06c1d6bba79ec6395801 564 PRINTS PR01165 Cytochrome c oxidase subunit I signature 388 407 1.6E-101 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK77_RS12875 c82f39ebd2bf06c1d6bba79ec6395801 564 PRINTS PR01165 Cytochrome c oxidase subunit I signature 438 459 1.6E-101 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK77_RS12875 c82f39ebd2bf06c1d6bba79ec6395801 564 SUPERFAMILY SSF81442 28 537 1.44E-175 T 06-07-2017 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK77_RS12875 c82f39ebd2bf06c1d6bba79ec6395801 564 Gene3D G3DSA:1.20.210.10 25 555 4.4E-193 T 06-07-2017 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK77_RS12875 c82f39ebd2bf06c1d6bba79ec6395801 564 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 259 313 - T 06-07-2017 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK77_RS13360 d2138d4c15f2fe522609aebbd26c2186 240 Pfam PF00877 NlpC/P60 family 123 237 8.3E-30 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain CAK77_RS13360 d2138d4c15f2fe522609aebbd26c2186 240 Gene3D G3DSA:3.90.1720.10 108 238 5.8E-39 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain CAK77_RS13360 d2138d4c15f2fe522609aebbd26c2186 240 SUPERFAMILY SSF54001 107 237 3.83E-32 T 06-07-2017 CAK77_RS06030 8b4c737886e4c89e9a582d65ae180acf 164 SUPERFAMILY SSF46557 7 78 6.8E-23 T 06-07-2017 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 CAK77_RS06030 8b4c737886e4c89e9a582d65ae180acf 164 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 8 158 6.0E-44 T 06-07-2017 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 CAK77_RS06030 8b4c737886e4c89e9a582d65ae180acf 164 Pfam PF03449 Transcription elongation factor, N-terminal 8 76 1.8E-24 T 06-07-2017 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 CAK77_RS06030 8b4c737886e4c89e9a582d65ae180acf 164 Gene3D G3DSA:1.10.287.180 5 76 1.8E-26 T 06-07-2017 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 CAK77_RS06030 8b4c737886e4c89e9a582d65ae180acf 164 Gene3D G3DSA:3.10.50.30 78 162 1.6E-14 T 06-07-2017 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 CAK77_RS06030 8b4c737886e4c89e9a582d65ae180acf 164 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 124 140 - T 06-07-2017 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 CAK77_RS06030 8b4c737886e4c89e9a582d65ae180acf 164 Hamap MF_00105 Transcription elongation factor GreA [greA]. 5 160 28.567 T 06-07-2017 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 CAK77_RS06030 8b4c737886e4c89e9a582d65ae180acf 164 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 83 160 1.3E-13 T 06-07-2017 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 CAK77_RS06030 8b4c737886e4c89e9a582d65ae180acf 164 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 20 50 - T 06-07-2017 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 CAK77_RS06030 8b4c737886e4c89e9a582d65ae180acf 164 SUPERFAMILY SSF54534 81 160 4.84E-11 T 06-07-2017 CAK77_RS06030 8b4c737886e4c89e9a582d65ae180acf 164 PIRSF PIRSF006092 1 163 1.6E-31 T 06-07-2017 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 CAK77_RS16805 2cdb28c2c43440f2db0f3996b8c3213e 430 Gene3D G3DSA:2.140.10.10 5 428 2.7E-19 T 06-07-2017 IPR027295 Quinoprotein alcohol dehydrogenase-like domain CAK77_RS16805 2cdb28c2c43440f2db0f3996b8c3213e 430 SUPERFAMILY SSF50998 222 428 3.4E-16 T 06-07-2017 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily CAK77_RS16805 2cdb28c2c43440f2db0f3996b8c3213e 430 Pfam PF13360 PQQ-like domain 222 398 2.5E-9 T 06-07-2017 IPR002372 Pyrrolo-quinoline quinone repeat CAK77_RS08650 4f1a2aff6b36e29e4ed7fde806696831 338 Pfam PF02470 MlaD protein 39 112 5.4E-14 T 06-07-2017 IPR003399 Mce/MlaD CAK77_RS08650 4f1a2aff6b36e29e4ed7fde806696831 338 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 14 288 3.1E-49 T 06-07-2017 IPR005693 Virulence factor Mce protein CAK77_RS08650 4f1a2aff6b36e29e4ed7fde806696831 338 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 90 106 1.9E-5 T 06-07-2017 IPR005693 Virulence factor Mce protein CAK77_RS08650 4f1a2aff6b36e29e4ed7fde806696831 338 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 127 151 1.9E-5 T 06-07-2017 IPR005693 Virulence factor Mce protein CAK77_RS08650 4f1a2aff6b36e29e4ed7fde806696831 338 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 176 194 1.9E-5 T 06-07-2017 IPR005693 Virulence factor Mce protein CAK77_RS06290 b97d88da4df779ac9e422e1ccf9dd985 69 PIRSF PIRSF006488 1 69 2.4E-24 T 06-07-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CAK77_RS06290 b97d88da4df779ac9e422e1ccf9dd985 69 Gene3D G3DSA:1.10.287.1040 8 67 2.2E-22 T 06-07-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CAK77_RS06290 b97d88da4df779ac9e422e1ccf9dd985 69 SUPERFAMILY SSF116842 6 66 3.01E-17 T 06-07-2017 CAK77_RS06290 b97d88da4df779ac9e422e1ccf9dd985 69 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 13 53 1.0E-11 T 06-07-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CAK77_RS06290 b97d88da4df779ac9e422e1ccf9dd985 69 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 12 69 11.87 T 06-07-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CAK77_RS06290 b97d88da4df779ac9e422e1ccf9dd985 69 Pfam PF02609 Exonuclease VII small subunit 13 63 3.2E-18 T 06-07-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CAK77_RS06290 b97d88da4df779ac9e422e1ccf9dd985 69 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 13 67 1.4E-21 T 06-07-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CAK77_RS07550 e9807b2ebbe09de4678463aed394495b 228 Gene3D G3DSA:3.40.50.1000 55 224 6.2E-30 T 06-07-2017 IPR023214 HAD-like domain CAK77_RS07550 e9807b2ebbe09de4678463aed394495b 228 TIGRFAM TIGR03351 PhnX-like: phosphonatase-like hydrolase 6 224 2.0E-69 T 06-07-2017 IPR022468 Phosphonatase-like hydrolase CAK77_RS07550 e9807b2ebbe09de4678463aed394495b 228 SUPERFAMILY SSF56784 6 223 3.52E-34 T 06-07-2017 IPR023214 HAD-like domain CAK77_RS07550 e9807b2ebbe09de4678463aed394495b 228 Pfam PF13419 Haloacid dehalogenase-like hydrolase 25 193 1.7E-16 T 06-07-2017 IPR023214 HAD-like domain CAK77_RS18670 88c7e5190e3e961b1dd2e0abd6985fd2 621 Pfam PF13522 Glutamine amidotransferase domain 65 199 2.8E-20 T 06-07-2017 CAK77_RS18670 88c7e5190e3e961b1dd2e0abd6985fd2 621 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 621 1.2E-246 T 06-07-2017 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 CAK77_RS18670 88c7e5190e3e961b1dd2e0abd6985fd2 621 SUPERFAMILY SSF53697 254 621 2.6E-106 T 06-07-2017 CAK77_RS18670 88c7e5190e3e961b1dd2e0abd6985fd2 621 Pfam PF01380 SIS domain 470 599 6.0E-21 T 06-07-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 CAK77_RS18670 88c7e5190e3e961b1dd2e0abd6985fd2 621 Pfam PF01380 SIS domain 297 420 2.7E-32 T 06-07-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 CAK77_RS18670 88c7e5190e3e961b1dd2e0abd6985fd2 621 SUPERFAMILY SSF56235 2 235 2.06E-64 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAK77_RS18670 88c7e5190e3e961b1dd2e0abd6985fd2 621 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 621 40.697 T 06-07-2017 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 CAK77_RS18670 88c7e5190e3e961b1dd2e0abd6985fd2 621 Gene3D G3DSA:3.40.50.10490 451 621 1.6E-61 T 06-07-2017 CAK77_RS18670 88c7e5190e3e961b1dd2e0abd6985fd2 621 Gene3D G3DSA:3.60.20.10 2 238 5.2E-73 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAK77_RS18670 88c7e5190e3e961b1dd2e0abd6985fd2 621 Gene3D G3DSA:3.40.50.10490 253 450 2.3E-68 T 06-07-2017 CAK77_RS11465 d82e458fc4e3b581467dd9c9240b257e 552 Gene3D G3DSA:3.40.50.300 163 272 6.2E-36 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS11465 d82e458fc4e3b581467dd9c9240b257e 552 Gene3D G3DSA:3.40.50.300 4 124 6.2E-36 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS11465 d82e458fc4e3b581467dd9c9240b257e 552 Gene3D G3DSA:3.40.50.300 353 550 3.0E-27 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS11465 d82e458fc4e3b581467dd9c9240b257e 552 Pfam PF00005 ABC transporter 20 191 1.2E-18 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK77_RS11465 d82e458fc4e3b581467dd9c9240b257e 552 Pfam PF00005 ABC transporter 352 496 1.5E-11 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK77_RS11465 d82e458fc4e3b581467dd9c9240b257e 552 SMART SM00382 356 549 1.8E-4 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS11465 d82e458fc4e3b581467dd9c9240b257e 552 SMART SM00382 29 235 9.0E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS11465 d82e458fc4e3b581467dd9c9240b257e 552 SUPERFAMILY SSF52540 348 547 1.11E-28 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS11465 d82e458fc4e3b581467dd9c9240b257e 552 SUPERFAMILY SSF52540 15 234 3.22E-35 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS11635 cb7e8bfbb3c0d39a34b95668ddeaff22 772 Pfam PF07517 SecA DEAD-like domain 16 387 2.0E-85 T 06-07-2017 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 CAK77_RS11635 cb7e8bfbb3c0d39a34b95668ddeaff22 772 Pfam PF07516 SecA Wing and Scaffold domain 634 718 4.4E-14 T 06-07-2017 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CAK77_RS11635 cb7e8bfbb3c0d39a34b95668ddeaff22 772 ProSitePatterns PS01312 SecA family signature. 487 502 - T 06-07-2017 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 CAK77_RS11635 cb7e8bfbb3c0d39a34b95668ddeaff22 772 SUPERFAMILY SSF52540 404 564 5.76E-42 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS11635 cb7e8bfbb3c0d39a34b95668ddeaff22 772 Gene3D G3DSA:1.10.3060.10 591 724 2.2E-27 T 06-07-2017 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CAK77_RS11635 cb7e8bfbb3c0d39a34b95668ddeaff22 772 Gene3D G3DSA:3.40.50.300 404 561 1.2E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS11635 cb7e8bfbb3c0d39a34b95668ddeaff22 772 TIGRFAM TIGR04221 SecA2_Mycobac: accessory Sec system translocase SecA2 12 771 0.0 T 06-07-2017 IPR026389 Protein translocase subunit SecA, Actinobacteria-type CAK77_RS11635 cb7e8bfbb3c0d39a34b95668ddeaff22 772 SUPERFAMILY SSF81886 584 736 5.36E-30 T 06-07-2017 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CAK77_RS11635 cb7e8bfbb3c0d39a34b95668ddeaff22 772 Gene3D G3DSA:3.90.1440.10 241 353 2.1E-30 T 06-07-2017 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CAK77_RS11635 cb7e8bfbb3c0d39a34b95668ddeaff22 772 Pfam PF01043 SecA preprotein cross-linking domain 245 345 1.1E-20 T 06-07-2017 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CAK77_RS11635 cb7e8bfbb3c0d39a34b95668ddeaff22 772 SMART SM00958 232 345 2.6E-24 T 06-07-2017 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CAK77_RS11635 cb7e8bfbb3c0d39a34b95668ddeaff22 772 SUPERFAMILY SSF52540 9 232 7.18E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS11635 cb7e8bfbb3c0d39a34b95668ddeaff22 772 SUPERFAMILY SSF52540 518 561 7.18E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS11635 cb7e8bfbb3c0d39a34b95668ddeaff22 772 SUPERFAMILY SSF81767 244 353 4.97E-29 T 06-07-2017 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CAK77_RS11635 cb7e8bfbb3c0d39a34b95668ddeaff22 772 Gene3D G3DSA:3.40.50.300 356 402 1.5E-78 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS11635 cb7e8bfbb3c0d39a34b95668ddeaff22 772 Gene3D G3DSA:3.40.50.300 5 233 1.5E-78 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS11635 cb7e8bfbb3c0d39a34b95668ddeaff22 772 Hamap MF_01382 Protein translocase subunit SecA [secA]. 13 730 15.303 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CAK77_RS11635 cb7e8bfbb3c0d39a34b95668ddeaff22 772 SMART SM00957 14 389 1.4E-136 T 06-07-2017 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 CAK77_RS11635 cb7e8bfbb3c0d39a34b95668ddeaff22 772 PRINTS PR00906 SecA protein signature 175 195 3.0E-41 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CAK77_RS11635 cb7e8bfbb3c0d39a34b95668ddeaff22 772 PRINTS PR00906 SecA protein signature 68 92 3.0E-41 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CAK77_RS11635 cb7e8bfbb3c0d39a34b95668ddeaff22 772 PRINTS PR00906 SecA protein signature 326 348 3.0E-41 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CAK77_RS11635 cb7e8bfbb3c0d39a34b95668ddeaff22 772 PRINTS PR00906 SecA protein signature 106 120 3.0E-41 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CAK77_RS11635 cb7e8bfbb3c0d39a34b95668ddeaff22 772 PRINTS PR00906 SecA protein signature 122 132 3.0E-41 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CAK77_RS11635 cb7e8bfbb3c0d39a34b95668ddeaff22 772 PRINTS PR00906 SecA protein signature 363 380 3.0E-41 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CAK77_RS11635 cb7e8bfbb3c0d39a34b95668ddeaff22 772 PRINTS PR00906 SecA protein signature 400 413 3.0E-41 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CAK77_RS06695 e8737983749dbc844528803a598e404c 322 Hamap MF_02122 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [dapD]. 1 320 43.156 T 06-07-2017 IPR026586 Type 2 tetrahydrodipicolinate N-succinyltransferase family GO:0008666 KEGG: 00300+2.3.1.117 CAK77_RS06695 e8737983749dbc844528803a598e404c 322 SUPERFAMILY SSF51161 77 302 1.07E-38 T 06-07-2017 IPR011004 Trimeric LpxA-like CAK77_RS06695 e8737983749dbc844528803a598e404c 322 TIGRFAM TIGR03535 DapD_actino: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase 3 322 1.2E-154 T 06-07-2017 IPR019875 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, actinobacteria KEGG: 00300+2.3.1.117 CAK77_RS06695 e8737983749dbc844528803a598e404c 322 Pfam PF14789 Tetrahydrodipicolinate N-succinyltransferase middle 112 155 1.0E-18 T 06-07-2017 IPR032784 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, middle domain KEGG: 00300+2.3.1.117 CAK77_RS06695 e8737983749dbc844528803a598e404c 322 Gene3D G3DSA:3.30.60.70 112 155 2.9E-5 T 06-07-2017 IPR032784 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, middle domain KEGG: 00300+2.3.1.117 CAK77_RS06695 e8737983749dbc844528803a598e404c 322 Gene3D G3DSA:2.160.10.10 157 305 1.1E-32 T 06-07-2017 CAK77_RS06695 e8737983749dbc844528803a598e404c 322 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 237 269 4.0E-13 T 06-07-2017 IPR001451 Hexapeptide repeat CAK77_RS13875 ff19d61c3c5d248331565f2c0ee1fdf2 187 SUPERFAMILY SSF50249 129 185 5.31E-18 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS13875 ff19d61c3c5d248331565f2c0ee1fdf2 187 Hamap MF_00141 Elongation factor P [efp]. 1 185 49.431 T 06-07-2017 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 CAK77_RS13875 ff19d61c3c5d248331565f2c0ee1fdf2 187 Gene3D G3DSA:2.40.50.140 128 185 5.5E-29 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS13875 ff19d61c3c5d248331565f2c0ee1fdf2 187 TIGRFAM TIGR00038 efp: translation elongation factor P 3 185 1.4E-76 T 06-07-2017 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 CAK77_RS13875 ff19d61c3c5d248331565f2c0ee1fdf2 187 Pfam PF09285 Elongation factor P, C-terminal 129 184 2.0E-26 T 06-07-2017 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 CAK77_RS13875 ff19d61c3c5d248331565f2c0ee1fdf2 187 Pfam PF01132 Elongation factor P (EF-P) OB domain 68 120 8.9E-21 T 06-07-2017 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 CAK77_RS13875 ff19d61c3c5d248331565f2c0ee1fdf2 187 SUPERFAMILY SSF50104 3 63 5.18E-20 T 06-07-2017 IPR008991 Translation protein SH3-like domain CAK77_RS13875 ff19d61c3c5d248331565f2c0ee1fdf2 187 SMART SM00841 129 184 1.0E-34 T 06-07-2017 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 CAK77_RS13875 ff19d61c3c5d248331565f2c0ee1fdf2 187 PIRSF PIRSF005901 1 186 1.4E-67 T 06-07-2017 IPR020599 Translation elongation factor P/YeiP CAK77_RS13875 ff19d61c3c5d248331565f2c0ee1fdf2 187 Gene3D G3DSA:2.40.50.140 65 126 1.6E-23 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS13875 ff19d61c3c5d248331565f2c0ee1fdf2 187 SMART SM01185 67 121 1.9E-25 T 06-07-2017 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 CAK77_RS13875 ff19d61c3c5d248331565f2c0ee1fdf2 187 SUPERFAMILY SSF50249 65 126 9.85E-18 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS13875 ff19d61c3c5d248331565f2c0ee1fdf2 187 ProSitePatterns PS01275 Elongation factor P signature. 150 169 - T 06-07-2017 IPR013852 Translation elongation factor P/YeiP, conserved site CAK77_RS13875 ff19d61c3c5d248331565f2c0ee1fdf2 187 Gene3D G3DSA:2.30.30.30 3 63 1.9E-32 T 06-07-2017 IPR014722 Ribosomal protein L2 domain 2 CAK77_RS13875 ff19d61c3c5d248331565f2c0ee1fdf2 187 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 3 60 6.2E-27 T 06-07-2017 IPR013185 Translation elongation factor, KOW-like CAK77_RS08960 6c6ffb067a10e25ed0cc8aca5cbee664 386 SUPERFAMILY SSF56645 12 249 1.14E-74 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK77_RS08960 6c6ffb067a10e25ed0cc8aca5cbee664 386 Gene3D G3DSA:1.10.540.10 14 126 1.8E-32 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS08960 6c6ffb067a10e25ed0cc8aca5cbee664 386 SUPERFAMILY SSF47203 238 386 1.29E-44 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS08960 6c6ffb067a10e25ed0cc8aca5cbee664 386 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 14 125 7.4E-30 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS08960 6c6ffb067a10e25ed0cc8aca5cbee664 386 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 129 224 8.5E-24 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAK77_RS08960 6c6ffb067a10e25ed0cc8aca5cbee664 386 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 240 386 3.8E-42 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS08960 6c6ffb067a10e25ed0cc8aca5cbee664 386 Gene3D G3DSA:2.40.110.10 129 225 1.0E-34 T 06-07-2017 CAK77_RS08960 6c6ffb067a10e25ed0cc8aca5cbee664 386 Gene3D G3DSA:1.20.140.10 226 386 7.5E-53 T 06-07-2017 CAK77_RS23545 2ddc8a8437cf3c78a6da4d78840eee17 254 Gene3D G3DSA:3.20.190.10 2 97 1.3E-13 T 06-07-2017 CAK77_RS23545 2ddc8a8437cf3c78a6da4d78840eee17 254 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 122 184 1.2E-10 T 06-07-2017 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 CAK77_RS23545 2ddc8a8437cf3c78a6da4d78840eee17 254 SMART SM00898 2 108 8.9E-17 T 06-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CAK77_RS23545 2ddc8a8437cf3c78a6da4d78840eee17 254 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 96 2.2E-9 T 06-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CAK77_RS23545 2ddc8a8437cf3c78a6da4d78840eee17 254 ProSitePatterns PS01242 Zinc finger FPG-type signature. 229 253 - T 06-07-2017 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 CAK77_RS23545 2ddc8a8437cf3c78a6da4d78840eee17 254 SUPERFAMILY SSF57716 204 253 4.28E-12 T 06-07-2017 CAK77_RS23545 2ddc8a8437cf3c78a6da4d78840eee17 254 Pfam PF06827 Zinc finger found in FPG and IleRS 226 253 5.8E-6 T 06-07-2017 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 CAK77_RS23545 2ddc8a8437cf3c78a6da4d78840eee17 254 SUPERFAMILY SSF81624 2 123 6.02E-24 T 06-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CAK77_RS23545 2ddc8a8437cf3c78a6da4d78840eee17 254 SMART SM01232 122 210 3.5E-24 T 06-07-2017 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 CAK77_RS23545 2ddc8a8437cf3c78a6da4d78840eee17 254 Gene3D G3DSA:1.10.8.50 122 254 6.2E-37 T 06-07-2017 CAK77_RS23545 2ddc8a8437cf3c78a6da4d78840eee17 254 SUPERFAMILY SSF46946 121 186 1.31E-17 T 06-07-2017 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 CAK77_RS21685 5f30d5fa2466c09580082d3356fa76ea 143 Pfam PF05423 Mycobacterium membrane protein 5 142 2.0E-43 T 06-07-2017 IPR008693 Transport accessory protein MmpS CAK77_RS02975 ee4202edfdb5f8a9d4965ecaf33a3313 332 Gene3D G3DSA:3.20.20.190 258 329 6.1E-75 T 06-07-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CAK77_RS02975 ee4202edfdb5f8a9d4965ecaf33a3313 332 Gene3D G3DSA:3.20.20.190 21 225 6.1E-75 T 06-07-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CAK77_RS02975 ee4202edfdb5f8a9d4965ecaf33a3313 332 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 30 313 1.4E-37 T 06-07-2017 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 CAK77_RS02975 ee4202edfdb5f8a9d4965ecaf33a3313 332 SUPERFAMILY SSF51695 26 318 2.88E-55 T 06-07-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CAK77_RS03195 025dac88e5481b028eb14901b577d808 130 SUPERFAMILY SSF54637 3 119 3.3E-13 T 06-07-2017 IPR029069 HotDog domain CAK77_RS03195 025dac88e5481b028eb14901b577d808 130 Gene3D G3DSA:3.10.129.10 3 118 3.4E-13 T 06-07-2017 IPR029069 HotDog domain CAK77_RS03195 025dac88e5481b028eb14901b577d808 130 Pfam PF01575 MaoC like domain 15 112 1.1E-4 T 06-07-2017 IPR002539 MaoC-like domain CAK77_RS19305 7f8ace5cf3159ec775059d56cddb3d29 1319 Pfam PF05000 RNA polymerase Rpb1, domain 4 770 831 1.7E-6 T 06-07-2017 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK77_RS19305 7f8ace5cf3159ec775059d56cddb3d29 1319 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 5 1280 9.931 T 06-07-2017 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK77_RS19305 7f8ace5cf3159ec775059d56cddb3d29 1319 SMART SM00663 310 589 3.9E-171 T 06-07-2017 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK77_RS19305 7f8ace5cf3159ec775059d56cddb3d29 1319 SUPERFAMILY SSF64484 5 1271 0.0 T 06-07-2017 CAK77_RS19305 7f8ace5cf3159ec775059d56cddb3d29 1319 Pfam PF04997 RNA polymerase Rpb1, domain 1 7 417 2.0E-82 T 06-07-2017 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK77_RS19305 7f8ace5cf3159ec775059d56cddb3d29 1319 Pfam PF04983 RNA polymerase Rpb1, domain 3 564 735 2.9E-26 T 06-07-2017 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK77_RS19305 7f8ace5cf3159ec775059d56cddb3d29 1319 Pfam PF04998 RNA polymerase Rpb1, domain 5 842 1219 8.1E-63 T 06-07-2017 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK77_RS19305 7f8ace5cf3159ec775059d56cddb3d29 1319 Pfam PF00623 RNA polymerase Rpb1, domain 2 419 460 8.5E-8 T 06-07-2017 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK77_RS19305 7f8ace5cf3159ec775059d56cddb3d29 1319 Pfam PF00623 RNA polymerase Rpb1, domain 2 467 560 1.9E-28 T 06-07-2017 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK77_RS19305 7f8ace5cf3159ec775059d56cddb3d29 1319 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 10 1271 0.0 T 06-07-2017 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK77_RS19305 7f8ace5cf3159ec775059d56cddb3d29 1319 Gene3D G3DSA:2.40.40.20 424 451 7.2E-38 T 06-07-2017 CAK77_RS19305 7f8ace5cf3159ec775059d56cddb3d29 1319 Gene3D G3DSA:2.40.40.20 492 564 7.2E-38 T 06-07-2017 CAK77_RS04835 040188f77bfe90ffc10fb91c612bd1e2 369 Gene3D G3DSA:3.90.180.10 20 198 1.6E-57 T 06-07-2017 IPR011032 GroES-like CAK77_RS04835 040188f77bfe90ffc10fb91c612bd1e2 369 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 68 82 - T 06-07-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CAK77_RS04835 040188f77bfe90ffc10fb91c612bd1e2 369 SUPERFAMILY SSF51735 167 329 3.46E-39 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS04835 040188f77bfe90ffc10fb91c612bd1e2 369 Gene3D G3DSA:3.40.50.720 199 308 2.0E-30 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS04835 040188f77bfe90ffc10fb91c612bd1e2 369 SMART SM00829 18 363 0.0016 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAK77_RS04835 040188f77bfe90ffc10fb91c612bd1e2 369 Pfam PF00107 Zinc-binding dehydrogenase 205 322 2.0E-19 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAK77_RS04835 040188f77bfe90ffc10fb91c612bd1e2 369 SUPERFAMILY SSF50129 20 201 1.46E-57 T 06-07-2017 IPR011032 GroES-like CAK77_RS04835 040188f77bfe90ffc10fb91c612bd1e2 369 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 35 156 4.9E-26 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAK77_RS15230 dcfe9f588c5c222af4124b54d3fe5159 204 Hamap MF_01114 Regulatory protein RecX [recX]. 18 197 14.843 T 06-07-2017 IPR003783 Regulatory protein RecX GO:0006282 CAK77_RS15230 dcfe9f588c5c222af4124b54d3fe5159 204 Gene3D G3DSA:1.10.10.10 51 93 1.9E-8 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS15230 dcfe9f588c5c222af4124b54d3fe5159 204 Gene3D G3DSA:1.10.10.10 95 139 7.9E-7 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS15230 dcfe9f588c5c222af4124b54d3fe5159 204 Pfam PF02631 RecX family 71 192 7.2E-26 T 06-07-2017 IPR003783 Regulatory protein RecX GO:0006282 CAK77_RS01060 8d419efaa231f288da6a22e1792f2ad0 637 SUPERFAMILY SSF56801 21 368 2.09E-88 T 06-07-2017 CAK77_RS01060 8d419efaa231f288da6a22e1792f2ad0 637 SUPERFAMILY SSF56801 395 621 2.09E-88 T 06-07-2017 CAK77_RS01060 8d419efaa231f288da6a22e1792f2ad0 637 Gene3D G3DSA:3.40.50.980 190 365 3.2E-23 T 06-07-2017 CAK77_RS01060 8d419efaa231f288da6a22e1792f2ad0 637 Gene3D G3DSA:3.30.300.30 489 615 2.0E-11 T 06-07-2017 CAK77_RS01060 8d419efaa231f288da6a22e1792f2ad0 637 Gene3D G3DSA:2.30.38.10 397 488 3.4E-18 T 06-07-2017 CAK77_RS01060 8d419efaa231f288da6a22e1792f2ad0 637 Pfam PF00501 AMP-binding enzyme 41 497 1.7E-69 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK77_RS01060 8d419efaa231f288da6a22e1792f2ad0 637 Gene3D G3DSA:3.40.50.980 20 189 1.2E-25 T 06-07-2017 CAK77_RS02895 13af8e32c6b3e76b435d055cc4ccc6a8 318 Pfam PF12833 Helix-turn-helix domain 233 311 4.7E-22 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK77_RS02895 13af8e32c6b3e76b435d055cc4ccc6a8 318 Pfam PF01965 DJ-1/PfpI family 4 172 1.8E-15 T 06-07-2017 IPR002818 DJ-1/PfpI CAK77_RS02895 13af8e32c6b3e76b435d055cc4ccc6a8 318 SUPERFAMILY SSF46689 215 261 1.36E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS02895 13af8e32c6b3e76b435d055cc4ccc6a8 318 SUPERFAMILY SSF52317 4 193 8.86E-44 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAK77_RS02895 13af8e32c6b3e76b435d055cc4ccc6a8 318 Gene3D G3DSA:1.10.10.60 215 264 3.1E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS02895 13af8e32c6b3e76b435d055cc4ccc6a8 318 SMART SM00342 227 310 2.0E-24 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK77_RS02895 13af8e32c6b3e76b435d055cc4ccc6a8 318 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 264 306 - T 06-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CAK77_RS02895 13af8e32c6b3e76b435d055cc4ccc6a8 318 Gene3D G3DSA:3.40.50.880 5 206 3.6E-47 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAK77_RS02895 13af8e32c6b3e76b435d055cc4ccc6a8 318 Gene3D G3DSA:1.10.10.60 265 312 1.6E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS02895 13af8e32c6b3e76b435d055cc4ccc6a8 318 SUPERFAMILY SSF46689 264 313 1.53E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS17300 db4c93a90457c6a0ef1a450ddd767124 457 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 258 269 - T 06-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CAK77_RS17300 db4c93a90457c6a0ef1a450ddd767124 457 Gene3D G3DSA:3.40.309.10 245 429 2.2E-66 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAK77_RS17300 db4c93a90457c6a0ef1a450ddd767124 457 Gene3D G3DSA:3.40.605.10 3 244 1.2E-74 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAK77_RS17300 db4c93a90457c6a0ef1a450ddd767124 457 Pfam PF00171 Aldehyde dehydrogenase family 3 454 3.3E-145 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAK77_RS17300 db4c93a90457c6a0ef1a450ddd767124 457 SUPERFAMILY SSF53720 3 456 9.95E-149 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAK77_RS20925 6b4567e355ddaf70821e5b8fed67afed 143 Gene3D G3DSA:3.50.80.10 2 142 2.4E-52 T 06-07-2017 IPR023509 D-Tyr tRNAtyr deacylase-like domain CAK77_RS20925 6b4567e355ddaf70821e5b8fed67afed 143 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 2 142 2.3E-49 T 06-07-2017 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 CAK77_RS20925 6b4567e355ddaf70821e5b8fed67afed 143 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 143 31.111 T 06-07-2017 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 CAK77_RS20925 6b4567e355ddaf70821e5b8fed67afed 143 SUPERFAMILY SSF69500 1 142 7.19E-46 T 06-07-2017 IPR023509 D-Tyr tRNAtyr deacylase-like domain CAK77_RS20925 6b4567e355ddaf70821e5b8fed67afed 143 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 2 142 1.7E-42 T 06-07-2017 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 CAK77_RS11550 8c149d7a01dbcd6a854ee287d2d79afe 466 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 255 270 4.4E-7 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 CAK77_RS11550 8c149d7a01dbcd6a854ee287d2d79afe 466 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 206 226 4.4E-7 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 CAK77_RS11550 8c149d7a01dbcd6a854ee287d2d79afe 466 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 32 457 1.5E-156 T 06-07-2017 IPR016484 GTP-binding protein EngA GO:0005525 CAK77_RS11550 8c149d7a01dbcd6a854ee287d2d79afe 466 Gene3D G3DSA:3.40.50.300 204 384 6.9E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS11550 8c149d7a01dbcd6a854ee287d2d79afe 466 Pfam PF01926 50S ribosome-binding GTPase 33 147 6.3E-24 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 CAK77_RS11550 8c149d7a01dbcd6a854ee287d2d79afe 466 Pfam PF01926 50S ribosome-binding GTPase 205 323 2.8E-22 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 CAK77_RS11550 8c149d7a01dbcd6a854ee287d2d79afe 466 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 379 457 1.9E-26 T 06-07-2017 IPR032859 GTPase Der, C-terminal KH-domain-like CAK77_RS11550 8c149d7a01dbcd6a854ee287d2d79afe 466 Hamap MF_00195 GTPase Der [der]. 30 460 35.054 T 06-07-2017 IPR016484 GTP-binding protein EngA GO:0005525 CAK77_RS11550 8c149d7a01dbcd6a854ee287d2d79afe 466 SUPERFAMILY SSF52540 165 461 1.88E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS11550 8c149d7a01dbcd6a854ee287d2d79afe 466 Gene3D G3DSA:3.40.50.300 25 188 1.5E-41 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS11550 8c149d7a01dbcd6a854ee287d2d79afe 466 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 32 184 5.1E-21 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 CAK77_RS11550 8c149d7a01dbcd6a854ee287d2d79afe 466 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 204 367 9.4E-24 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 CAK77_RS11550 8c149d7a01dbcd6a854ee287d2d79afe 466 Gene3D G3DSA:3.30.300.20 385 459 5.7E-29 T 06-07-2017 IPR015946 K homology domain-like, alpha/beta CAK77_RS11550 8c149d7a01dbcd6a854ee287d2d79afe 466 SMART SM00382 29 167 0.23 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS11550 8c149d7a01dbcd6a854ee287d2d79afe 466 SMART SM00382 202 447 2.2 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS11550 8c149d7a01dbcd6a854ee287d2d79afe 466 PIRSF PIRSF006485 30 465 2.7E-163 T 06-07-2017 IPR016484 GTP-binding protein EngA GO:0005525 CAK77_RS11550 8c149d7a01dbcd6a854ee287d2d79afe 466 SUPERFAMILY SSF52540 33 193 4.31E-41 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS17790 5fd740bd1f17c65d839c3488e286c2c1 476 Pfam PF06974 Protein of unknown function (DUF1298) 329 471 2.9E-22 T 06-07-2017 IPR009721 O-acyltransferase WSD1, C-terminal GO:0004144 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CAK77_RS17790 5fd740bd1f17c65d839c3488e286c2c1 476 SUPERFAMILY SSF52777 33 158 1.11E-6 T 06-07-2017 CAK77_RS17790 5fd740bd1f17c65d839c3488e286c2c1 476 Pfam PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain 12 278 6.5E-79 T 06-07-2017 IPR004255 O-acyltransferase, WSD1, N-terminal GO:0004144|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CAK77_RS17790 5fd740bd1f17c65d839c3488e286c2c1 476 TIGRFAM TIGR02946 acyl_WS_DGAT: acyltransferase, WS/DGAT/MGAT 12 475 4.4E-146 T 06-07-2017 IPR014292 Acyltransferase, WS/DGAT/MGAT GO:0016746|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CAK77_RS03600 23c5bedcf26683694cea0875d23488a8 552 Pfam PF00890 FAD binding domain 7 533 5.0E-107 T 06-07-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK77_RS03600 23c5bedcf26683694cea0875d23488a8 552 PIRSF PIRSF036654 2 551 1.5E-296 T 06-07-2017 IPR014614 Uncharacterised conserved protein UCP036654 GO:0016627|GO:0055114 CAK77_RS03600 23c5bedcf26683694cea0875d23488a8 552 SUPERFAMILY SSF51905 3 280 2.07E-35 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS03600 23c5bedcf26683694cea0875d23488a8 552 SUPERFAMILY SSF51905 488 550 2.07E-35 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS03600 23c5bedcf26683694cea0875d23488a8 552 Gene3D G3DSA:3.50.50.60 485 550 4.4E-68 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS03600 23c5bedcf26683694cea0875d23488a8 552 Gene3D G3DSA:3.50.50.60 3 275 4.4E-68 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS21125 3b4510d2555f7269ef71ffec4f74412b 324 Gene3D G3DSA:3.40.50.300 1 222 6.2E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS21125 3b4510d2555f7269ef71ffec4f74412b 324 SMART SM00382 26 204 2.1E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS21125 3b4510d2555f7269ef71ffec4f74412b 324 ProSitePatterns PS00211 ABC transporters family signature. 128 142 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK77_RS21125 3b4510d2555f7269ef71ffec4f74412b 324 SUPERFAMILY SSF52540 2 224 9.02E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS21125 3b4510d2555f7269ef71ffec4f74412b 324 Pfam PF00005 ABC transporter 18 156 3.3E-28 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK77_RS16710 d122ee072d78a43fa4855d584caae398 247 Gene3D G3DSA:3.40.50.720 1 205 5.9E-34 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS16710 d122ee072d78a43fa4855d584caae398 247 Pfam PF13460 NAD(P)H-binding 7 170 1.0E-15 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS16710 d122ee072d78a43fa4855d584caae398 247 SUPERFAMILY SSF51735 1 213 2.74E-37 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS13125 40bb1f2ec198940fb8d99011ede0d2d6 178 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 60 2.0E-15 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS13125 40bb1f2ec198940fb8d99011ede0d2d6 178 Gene3D G3DSA:1.10.357.10 7 170 2.9E-26 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS13125 40bb1f2ec198940fb8d99011ede0d2d6 178 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 5.7E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS13125 40bb1f2ec198940fb8d99011ede0d2d6 178 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 5.7E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS13125 40bb1f2ec198940fb8d99011ede0d2d6 178 SUPERFAMILY SSF46689 8 78 1.7E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS05650 2bb8814a2d12d0667877cbec0dc982ab 340 SUPERFAMILY SSF53901 7 334 2.46E-62 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS05650 2bb8814a2d12d0667877cbec0dc982ab 340 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 13 334 6.7E-124 T 06-07-2017 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CAK77_RS05650 2bb8814a2d12d0667877cbec0dc982ab 340 Gene3D G3DSA:3.40.47.10 170 333 7.4E-43 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS05650 2bb8814a2d12d0667877cbec0dc982ab 340 Gene3D G3DSA:3.40.47.10 11 169 8.3E-57 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS05650 2bb8814a2d12d0667877cbec0dc982ab 340 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 116 193 3.5E-26 T 06-07-2017 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CAK77_RS05650 2bb8814a2d12d0667877cbec0dc982ab 340 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 11 334 59.506 T 06-07-2017 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CAK77_RS05650 2bb8814a2d12d0667877cbec0dc982ab 340 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 244 334 1.9E-29 T 06-07-2017 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CAK77_RS14425 c78d46652cfe00856635736d653b93a5 680 Pfam PF02540 NAD synthase 348 521 2.6E-22 T 06-07-2017 IPR022310 NAD/GMP synthase CAK77_RS14425 c78d46652cfe00856635736d653b93a5 680 SUPERFAMILY SSF56317 10 294 5.76E-46 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAK77_RS14425 c78d46652cfe00856635736d653b93a5 680 PIRSF PIRSF006630 9 670 4.8E-169 T 06-07-2017 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|Reactome: R-HSA-196807 CAK77_RS14425 c78d46652cfe00856635736d653b93a5 680 Gene3D G3DSA:3.60.110.10 11 294 9.4E-50 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAK77_RS14425 c78d46652cfe00856635736d653b93a5 680 Gene3D G3DSA:3.40.50.620 619 647 1.3E-55 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS14425 c78d46652cfe00856635736d653b93a5 680 Gene3D G3DSA:3.40.50.620 326 578 1.3E-55 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS14425 c78d46652cfe00856635736d653b93a5 680 Pfam PF00795 Carbon-nitrogen hydrolase 13 281 1.2E-16 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAK77_RS14425 c78d46652cfe00856635736d653b93a5 680 SUPERFAMILY SSF52402 616 647 1.79E-61 T 06-07-2017 CAK77_RS14425 c78d46652cfe00856635736d653b93a5 680 SUPERFAMILY SSF52402 324 575 1.79E-61 T 06-07-2017 CAK77_RS07110 2cf1414d588500262a1a3ca46014b605 170 SMART SM00855 8 117 3.5E-5 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 CAK77_RS07110 2cf1414d588500262a1a3ca46014b605 170 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 9 69 1.8E-7 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 CAK77_RS07110 2cf1414d588500262a1a3ca46014b605 170 SUPERFAMILY SSF53254 8 153 1.36E-17 T 06-07-2017 IPR029033 Histidine phosphatase superfamily CAK77_RS07110 2cf1414d588500262a1a3ca46014b605 170 Gene3D G3DSA:3.40.50.1240 5 170 2.0E-46 T 06-07-2017 IPR029033 Histidine phosphatase superfamily CAK77_RS14735 bf945e638a7d47814098f1cf1a9dfd18 1183 Gene3D G3DSA:2.30.38.10 447 518 1.3E-13 T 06-07-2017 CAK77_RS14735 bf945e638a7d47814098f1cf1a9dfd18 1183 SUPERFAMILY SSF51735 793 1098 8.07E-28 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS14735 bf945e638a7d47814098f1cf1a9dfd18 1183 SUPERFAMILY SSF47336 667 756 6.67E-12 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS14735 bf945e638a7d47814098f1cf1a9dfd18 1183 Gene3D G3DSA:1.10.1200.10 668 759 4.0E-10 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS14735 bf945e638a7d47814098f1cf1a9dfd18 1183 ProSitePatterns PS00455 Putative AMP-binding domain signature. 259 270 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK77_RS14735 bf945e638a7d47814098f1cf1a9dfd18 1183 Gene3D G3DSA:3.40.50.720 794 1023 2.1E-25 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS14735 bf945e638a7d47814098f1cf1a9dfd18 1183 SUPERFAMILY SSF56801 52 648 1.01E-87 T 06-07-2017 CAK77_RS14735 bf945e638a7d47814098f1cf1a9dfd18 1183 Gene3D G3DSA:3.40.50.980 265 438 5.8E-22 T 06-07-2017 CAK77_RS14735 bf945e638a7d47814098f1cf1a9dfd18 1183 Pfam PF00550 Phosphopantetheine attachment site 671 735 2.1E-9 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS14735 bf945e638a7d47814098f1cf1a9dfd18 1183 Pfam PF00501 AMP-binding enzyme 90 526 3.2E-65 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK77_RS14735 bf945e638a7d47814098f1cf1a9dfd18 1183 Pfam PF07993 Male sterility protein 797 1059 5.5E-51 T 06-07-2017 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 CAK77_RS14735 bf945e638a7d47814098f1cf1a9dfd18 1183 TIGRFAM TIGR01746 Thioester-redct: thioester reductase domain 794 1183 3.3E-81 T 06-07-2017 IPR010080 Thioester reductase-like domain CAK77_RS14735 bf945e638a7d47814098f1cf1a9dfd18 1183 SMART SM00823 Phosphopantetheine attachment site 669 740 0.0017 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAK77_RS14735 bf945e638a7d47814098f1cf1a9dfd18 1183 Gene3D G3DSA:3.40.50.980 53 264 2.6E-23 T 06-07-2017 CAK77_RS13730 c2818020aa1d1a173248beb37c7c2c7d 340 SUPERFAMILY SSF53597 149 332 5.5E-46 T 06-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CAK77_RS13730 c2818020aa1d1a173248beb37c7c2c7d 340 Pfam PF01872 RibD C-terminal domain 152 332 2.6E-47 T 06-07-2017 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CAK77_RS13730 c2818020aa1d1a173248beb37c7c2c7d 340 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 9 104 3.7E-15 T 06-07-2017 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 CAK77_RS13730 c2818020aa1d1a173248beb37c7c2c7d 340 SUPERFAMILY SSF53927 10 137 2.45E-35 T 06-07-2017 IPR016193 Cytidine deaminase-like GO:0003824 CAK77_RS13730 c2818020aa1d1a173248beb37c7c2c7d 340 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 55 93 - T 06-07-2017 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 CAK77_RS13730 c2818020aa1d1a173248beb37c7c2c7d 340 Gene3D G3DSA:3.40.140.10 9 153 2.1E-24 T 06-07-2017 CAK77_RS13730 c2818020aa1d1a173248beb37c7c2c7d 340 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 11 332 3.0E-93 T 06-07-2017 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 CAK77_RS13730 c2818020aa1d1a173248beb37c7c2c7d 340 Gene3D G3DSA:3.40.430.10 154 336 4.0E-52 T 06-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CAK77_RS04180 23f37feb36dc6c97a0aa903dbc4328cd 452 Gene3D G3DSA:3.40.640.10 84 332 1.3E-81 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK77_RS04180 23f37feb36dc6c97a0aa903dbc4328cd 452 Pfam PF00202 Aminotransferase class-III 52 448 8.6E-115 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAK77_RS04180 23f37feb36dc6c97a0aa903dbc4328cd 452 SUPERFAMILY SSF53383 45 450 1.46E-119 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK77_RS04180 23f37feb36dc6c97a0aa903dbc4328cd 452 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 265 302 - T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAK77_RS04180 23f37feb36dc6c97a0aa903dbc4328cd 452 TIGRFAM TIGR00700 GABAtrnsam: 4-aminobutyrate transaminase 34 450 2.7E-165 T 06-07-2017 IPR004632 4-aminobutyrate aminotransferase, bacterial GO:0003867|GO:0009448 CAK77_RS04180 23f37feb36dc6c97a0aa903dbc4328cd 452 Gene3D G3DSA:3.90.1150.10 333 451 6.9E-38 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK77_RS00525 c4effb73145aebd8e042625c453babc2 537 SUPERFAMILY SSF51905 148 380 2.16E-44 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS00525 c4effb73145aebd8e042625c453babc2 537 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 179 204 9.2E-8 T 06-07-2017 CAK77_RS00525 c4effb73145aebd8e042625c453babc2 537 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 9 31 9.2E-8 T 06-07-2017 CAK77_RS00525 c4effb73145aebd8e042625c453babc2 537 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 137 146 9.2E-8 T 06-07-2017 CAK77_RS00525 c4effb73145aebd8e042625c453babc2 537 SUPERFAMILY SSF51905 7 229 3.15E-53 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS00525 c4effb73145aebd8e042625c453babc2 537 Gene3D G3DSA:3.50.50.60 420 529 4.5E-80 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS00525 c4effb73145aebd8e042625c453babc2 537 Gene3D G3DSA:3.50.50.60 6 184 4.5E-80 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS00525 c4effb73145aebd8e042625c453babc2 537 Gene3D G3DSA:3.50.50.60 185 228 9.3E-4 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS00525 c4effb73145aebd8e042625c453babc2 537 Gene3D G3DSA:3.50.50.60 282 283 9.3E-4 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS00525 c4effb73145aebd8e042625c453babc2 537 Gene3D G3DSA:3.50.50.60 345 392 9.3E-4 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS00525 c4effb73145aebd8e042625c453babc2 537 Pfam PF00743 Flavin-binding monooxygenase-like 10 211 7.2E-16 T 06-07-2017 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 CAK77_RS14035 10a05c0bf598ccc925f09562e763150a 143 Gene3D G3DSA:3.10.180.10 1 140 1.5E-27 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK77_RS14035 10a05c0bf598ccc925f09562e763150a 143 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 125 1.8E-8 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CAK77_RS14035 10a05c0bf598ccc925f09562e763150a 143 SUPERFAMILY SSF54593 3 135 5.1E-24 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK77_RS01145 f2b158adfe3c277f41d59e0b2eb10782 477 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 57 71 7.9E-6 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK77_RS01145 f2b158adfe3c277f41d59e0b2eb10782 477 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 71 87 7.9E-6 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK77_RS01145 f2b158adfe3c277f41d59e0b2eb10782 477 SUPERFAMILY SSF46785 32 105 8.6E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS01145 f2b158adfe3c277f41d59e0b2eb10782 477 SUPERFAMILY SSF53383 110 472 2.55E-69 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK77_RS01145 f2b158adfe3c277f41d59e0b2eb10782 477 Pfam PF00155 Aminotransferase class I and II 135 410 4.1E-12 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAK77_RS01145 f2b158adfe3c277f41d59e0b2eb10782 477 SMART SM00345 38 97 9.2E-16 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK77_RS01145 f2b158adfe3c277f41d59e0b2eb10782 477 Gene3D G3DSA:3.40.640.10 154 363 3.8E-39 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK77_RS01145 f2b158adfe3c277f41d59e0b2eb10782 477 Gene3D G3DSA:1.10.10.10 38 105 1.8E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS01145 f2b158adfe3c277f41d59e0b2eb10782 477 Pfam PF00392 Bacterial regulatory proteins, gntR family 40 97 3.4E-16 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK77_RS01080 2eed07d274207522e54f286e01e8ab15 324 SUPERFAMILY SSF160240 230 297 1.24E-8 T 06-07-2017 CAK77_RS01080 2eed07d274207522e54f286e01e8ab15 324 Gene3D G3DSA:1.20.1510.10 24 217 1.7E-49 T 06-07-2017 IPR027469 Cation efflux protein transmembrane domain CAK77_RS01080 2eed07d274207522e54f286e01e8ab15 324 SUPERFAMILY SSF161111 23 219 1.23E-49 T 06-07-2017 CAK77_RS01080 2eed07d274207522e54f286e01e8ab15 324 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 24 297 1.5E-73 T 06-07-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CAK77_RS01080 2eed07d274207522e54f286e01e8ab15 324 Pfam PF01545 Cation efflux family 27 217 2.3E-41 T 06-07-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CAK77_RS05265 611acee00c93a9327f1aa27983eace20 295 SMART SM01130 6 295 2.1E-102 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAK77_RS05265 611acee00c93a9327f1aa27983eace20 295 PIRSF PIRSF001365 2 294 1.7E-86 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAK77_RS05265 611acee00c93a9327f1aa27983eace20 295 PRINTS PR00146 Dihydrodipicolinate synthase signature 40 61 1.6E-11 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAK77_RS05265 611acee00c93a9327f1aa27983eace20 295 PRINTS PR00146 Dihydrodipicolinate synthase signature 76 94 1.6E-11 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAK77_RS05265 611acee00c93a9327f1aa27983eace20 295 PRINTS PR00146 Dihydrodipicolinate synthase signature 108 124 1.6E-11 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAK77_RS05265 611acee00c93a9327f1aa27983eace20 295 PRINTS PR00146 Dihydrodipicolinate synthase signature 133 150 1.6E-11 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAK77_RS05265 611acee00c93a9327f1aa27983eace20 295 Pfam PF00701 Dihydrodipicolinate synthetase family 7 292 2.5E-59 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAK77_RS05265 611acee00c93a9327f1aa27983eace20 295 Gene3D G3DSA:3.20.20.70 4 293 1.4E-98 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK77_RS05265 611acee00c93a9327f1aa27983eace20 295 SUPERFAMILY SSF51569 5 293 2.2E-87 T 06-07-2017 CAK77_RS14665 90c48d13ec56d0120f54427bdb332613 338 TIGRFAM TIGR02961 allantoicase: allantoicase 16 326 2.3E-114 T 06-07-2017 IPR005164 Allantoicase GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697 CAK77_RS14665 90c48d13ec56d0120f54427bdb332613 338 Pfam PF03561 Allantoicase repeat 24 176 4.4E-46 T 06-07-2017 IPR015908 Allantoicase domain GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697 CAK77_RS14665 90c48d13ec56d0120f54427bdb332613 338 Pfam PF03561 Allantoicase repeat 198 325 6.6E-36 T 06-07-2017 IPR015908 Allantoicase domain GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697 CAK77_RS14665 90c48d13ec56d0120f54427bdb332613 338 Hamap MF_00813 Probable allantoicase [alc]. 5 328 46.106 T 06-07-2017 IPR005164 Allantoicase GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697 CAK77_RS14665 90c48d13ec56d0120f54427bdb332613 338 Gene3D G3DSA:2.60.120.260 188 328 2.3E-39 T 06-07-2017 IPR008979 Galactose-binding domain-like CAK77_RS14665 90c48d13ec56d0120f54427bdb332613 338 Gene3D G3DSA:2.60.120.260 9 178 4.9E-55 T 06-07-2017 IPR008979 Galactose-binding domain-like CAK77_RS14665 90c48d13ec56d0120f54427bdb332613 338 SUPERFAMILY SSF49785 10 179 7.23E-52 T 06-07-2017 IPR008979 Galactose-binding domain-like CAK77_RS14665 90c48d13ec56d0120f54427bdb332613 338 SUPERFAMILY SSF49785 188 327 8.93E-41 T 06-07-2017 IPR008979 Galactose-binding domain-like CAK77_RS15400 f407051191b6420f40b1083dd10d5c9d 150 Gene3D G3DSA:3.40.50.360 1 149 5.7E-28 T 06-07-2017 IPR029039 Flavoprotein-like domain CAK77_RS15400 f407051191b6420f40b1083dd10d5c9d 150 SUPERFAMILY SSF52218 1 149 4.94E-24 T 06-07-2017 IPR029039 Flavoprotein-like domain CAK77_RS19820 0bee84dc49354e8b3597a625439edda1 249 PRINTS PR01703 Manganese superoxide dismutase signature 200 212 1.8E-21 T 06-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAK77_RS19820 0bee84dc49354e8b3597a625439edda1 249 PRINTS PR01703 Manganese superoxide dismutase signature 49 60 1.8E-21 T 06-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAK77_RS19820 0bee84dc49354e8b3597a625439edda1 249 PRINTS PR01703 Manganese superoxide dismutase signature 70 83 1.8E-21 T 06-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAK77_RS19820 0bee84dc49354e8b3597a625439edda1 249 PRINTS PR01703 Manganese superoxide dismutase signature 162 170 1.8E-21 T 06-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAK77_RS19820 0bee84dc49354e8b3597a625439edda1 249 PRINTS PR01703 Manganese superoxide dismutase signature 109 122 1.8E-21 T 06-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAK77_RS19820 0bee84dc49354e8b3597a625439edda1 249 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 133 235 1.1E-35 T 06-07-2017 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAK77_RS19820 0bee84dc49354e8b3597a625439edda1 249 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 46 126 1.1E-30 T 06-07-2017 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAK77_RS19820 0bee84dc49354e8b3597a625439edda1 249 SUPERFAMILY SSF54719 126 240 6.29E-44 T 06-07-2017 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAK77_RS19820 0bee84dc49354e8b3597a625439edda1 249 Gene3D G3DSA:1.10.287.990 63 126 6.1E-24 T 06-07-2017 CAK77_RS19820 0bee84dc49354e8b3597a625439edda1 249 SUPERFAMILY SSF46609 44 130 6.02E-30 T 06-07-2017 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAK77_RS19820 0bee84dc49354e8b3597a625439edda1 249 PIRSF PIRSF000349 16 244 7.7E-77 T 06-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAK77_RS19820 0bee84dc49354e8b3597a625439edda1 249 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 202 209 - T 06-07-2017 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAK77_RS22585 edabcc384ff4a0785737c2d2e4c5403b 386 SUPERFAMILY SSF56645 6 249 3.14E-72 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK77_RS22585 edabcc384ff4a0785737c2d2e4c5403b 386 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 236 384 8.9E-48 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS22585 edabcc384ff4a0785737c2d2e4c5403b 386 Gene3D G3DSA:2.40.110.10 124 224 2.9E-30 T 06-07-2017 CAK77_RS22585 edabcc384ff4a0785737c2d2e4c5403b 386 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 343 362 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CAK77_RS22585 edabcc384ff4a0785737c2d2e4c5403b 386 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 127 139 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CAK77_RS22585 edabcc384ff4a0785737c2d2e4c5403b 386 Gene3D G3DSA:1.10.540.10 6 121 5.9E-40 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS22585 edabcc384ff4a0785737c2d2e4c5403b 386 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 125 224 1.2E-17 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAK77_RS22585 edabcc384ff4a0785737c2d2e4c5403b 386 SUPERFAMILY SSF47203 234 385 1.59E-47 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS22585 edabcc384ff4a0785737c2d2e4c5403b 386 Gene3D G3DSA:1.20.140.10 225 385 4.5E-63 T 06-07-2017 CAK77_RS22585 edabcc384ff4a0785737c2d2e4c5403b 386 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 10 121 5.6E-35 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS00405 9f8e17f922f5aff64ccc58998f00a51a 97 SUPERFAMILY SSF140453 4 93 4.58E-7 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like CAK77_RS00405 9f8e17f922f5aff64ccc58998f00a51a 97 Gene3D G3DSA:1.10.287.1060 1 93 4.2E-14 T 06-07-2017 CAK77_RS10865 9f8e17f922f5aff64ccc58998f00a51a 97 SUPERFAMILY SSF140453 4 93 4.58E-7 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like CAK77_RS10865 9f8e17f922f5aff64ccc58998f00a51a 97 Gene3D G3DSA:1.10.287.1060 1 93 4.2E-14 T 06-07-2017 CAK77_RS03445 9f8e17f922f5aff64ccc58998f00a51a 97 SUPERFAMILY SSF140453 4 93 4.58E-7 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like CAK77_RS03445 9f8e17f922f5aff64ccc58998f00a51a 97 Gene3D G3DSA:1.10.287.1060 1 93 4.2E-14 T 06-07-2017 CAK77_RS19225 04de53c144367da7dbb83ddd79b588f9 202 SUPERFAMILY SSF46689 15 84 2.51E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS19225 04de53c144367da7dbb83ddd79b588f9 202 SUPERFAMILY SSF48498 90 198 5.16E-20 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS19225 04de53c144367da7dbb83ddd79b588f9 202 Gene3D G3DSA:1.10.357.10 71 198 1.6E-28 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS19225 04de53c144367da7dbb83ddd79b588f9 202 Pfam PF13305 WHG domain 97 175 1.1E-9 T 06-07-2017 IPR025996 WHG domain CAK77_RS19225 04de53c144367da7dbb83ddd79b588f9 202 Gene3D G3DSA:1.10.10.60 9 70 4.1E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS19225 04de53c144367da7dbb83ddd79b588f9 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 69 8.8E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS01530 4007af32114b0f217abdc902440a5105 618 Pfam PF00425 chorismate binding enzyme 127 375 1.4E-44 T 06-07-2017 IPR015890 Chorismate-utilising enzyme, C-terminal CAK77_RS01530 4007af32114b0f217abdc902440a5105 618 Pfam PF00117 Glutamine amidotransferase class-I 429 603 4.1E-20 T 06-07-2017 IPR017926 Glutamine amidotransferase CAK77_RS01530 4007af32114b0f217abdc902440a5105 618 PRINTS PR00096 Glutamine amidotransferase superfamily signature 468 477 3.0E-8 T 06-07-2017 CAK77_RS01530 4007af32114b0f217abdc902440a5105 618 PRINTS PR00096 Glutamine amidotransferase superfamily signature 586 599 3.0E-8 T 06-07-2017 CAK77_RS01530 4007af32114b0f217abdc902440a5105 618 PRINTS PR00096 Glutamine amidotransferase superfamily signature 501 512 3.0E-8 T 06-07-2017 CAK77_RS01530 4007af32114b0f217abdc902440a5105 618 Gene3D G3DSA:3.60.120.10 89 385 5.2E-55 T 06-07-2017 IPR005801 ADC synthase GO:0009058 CAK77_RS01530 4007af32114b0f217abdc902440a5105 618 PRINTS PR00097 Anthranilate synthase component II signature 427 441 9.6E-7 T 06-07-2017 CAK77_RS01530 4007af32114b0f217abdc902440a5105 618 PRINTS PR00097 Anthranilate synthase component II signature 468 477 9.6E-7 T 06-07-2017 CAK77_RS01530 4007af32114b0f217abdc902440a5105 618 PRINTS PR00097 Anthranilate synthase component II signature 586 599 9.6E-7 T 06-07-2017 CAK77_RS01530 4007af32114b0f217abdc902440a5105 618 Gene3D G3DSA:3.40.50.880 427 607 1.5E-26 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAK77_RS01530 4007af32114b0f217abdc902440a5105 618 SUPERFAMILY SSF56322 73 383 6.54E-60 T 06-07-2017 IPR005801 ADC synthase GO:0009058 CAK77_RS01530 4007af32114b0f217abdc902440a5105 618 SUPERFAMILY SSF52317 423 607 6.42E-24 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAK77_RS19535 e811982d59137d3e2b8ac5807b56ce60 506 Pfam PF00082 Subtilase family 150 495 4.6E-36 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CAK77_RS19535 e811982d59137d3e2b8ac5807b56ce60 506 PRINTS PR00723 Subtilisin serine protease family (S8) signature 444 460 1.2E-16 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related CAK77_RS19535 e811982d59137d3e2b8ac5807b56ce60 506 PRINTS PR00723 Subtilisin serine protease family (S8) signature 150 169 1.2E-16 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related CAK77_RS19535 e811982d59137d3e2b8ac5807b56ce60 506 PRINTS PR00723 Subtilisin serine protease family (S8) signature 200 213 1.2E-16 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related CAK77_RS19535 e811982d59137d3e2b8ac5807b56ce60 506 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 204 214 - T 06-07-2017 IPR022398 Peptidase S8, subtilisin, His-active site CAK77_RS19535 e811982d59137d3e2b8ac5807b56ce60 506 SUPERFAMILY SSF52743 248 503 2.23E-57 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CAK77_RS19535 e811982d59137d3e2b8ac5807b56ce60 506 SUPERFAMILY SSF52743 119 221 2.23E-57 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CAK77_RS19535 e811982d59137d3e2b8ac5807b56ce60 506 Gene3D G3DSA:3.40.50.200 132 503 5.9E-64 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CAK77_RS01580 4008a2ea807b70fd97a2698cde209a75 436 PIRSF PIRSF003085 16 436 1.6E-126 T 06-07-2017 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 CAK77_RS01580 4008a2ea807b70fd97a2698cde209a75 436 Pfam PF02353 Mycolic acid cyclopropane synthetase 146 415 2.5E-99 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS01580 4008a2ea807b70fd97a2698cde209a75 436 SMART SM00828 Methyltransferase in polyketide synthase (PKS) enzymes. 165 417 0.0026 T 06-07-2017 IPR020803 Polyketide synthase, methyltransferase domain CAK77_RS01580 4008a2ea807b70fd97a2698cde209a75 436 SUPERFAMILY SSF53335 157 419 3.25E-70 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS01580 4008a2ea807b70fd97a2698cde209a75 436 Gene3D G3DSA:3.40.50.150 146 419 7.7E-86 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS01695 1924848eec4a63c8045178147923b708 395 Gene3D G3DSA:3.40.50.300 35 189 1.3E-12 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS01695 1924848eec4a63c8045178147923b708 395 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 47 168 2.5E-8 T 06-07-2017 IPR003495 CobW/HypB/UreG, nucleotide-binding domain CAK77_RS01695 1924848eec4a63c8045178147923b708 395 SUPERFAMILY SSF90002 235 294 1.83E-5 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CAK77_RS01695 1924848eec4a63c8045178147923b708 395 SUPERFAMILY SSF90002 321 347 1.83E-5 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CAK77_RS01695 1924848eec4a63c8045178147923b708 395 Gene3D G3DSA:3.30.1220.10 227 344 5.8E-4 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CAK77_RS01695 1924848eec4a63c8045178147923b708 395 SMART SM00833 231 347 2.3E-34 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CAK77_RS01695 1924848eec4a63c8045178147923b708 395 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 234 346 1.3E-13 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CAK77_RS13670 17358897fcfe03b2991777379d33abf0 417 SUPERFAMILY SSF55821 5 209 2.75E-79 T 06-07-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain CAK77_RS13670 17358897fcfe03b2991777379d33abf0 417 SUPERFAMILY SSF142695 207 384 1.83E-69 T 06-07-2017 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CAK77_RS13670 17358897fcfe03b2991777379d33abf0 417 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 211 404 1.4E-76 T 06-07-2017 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CAK77_RS13670 17358897fcfe03b2991777379d33abf0 417 Pfam PF00925 GTP cyclohydrolase II 211 381 1.3E-73 T 06-07-2017 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CAK77_RS13670 17358897fcfe03b2991777379d33abf0 417 PIRSF PIRSF001259 2 411 1.4E-177 T 06-07-2017 CAK77_RS13670 17358897fcfe03b2991777379d33abf0 417 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 8 200 1.9E-82 T 06-07-2017 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CAK77_RS13670 17358897fcfe03b2991777379d33abf0 417 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 207 407 40.872 T 06-07-2017 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CAK77_RS13670 17358897fcfe03b2991777379d33abf0 417 Hamap MF_01283 Riboflavin biosynthesis protein RibBA [ribBA]. 3 403 56.452 T 06-07-2017 IPR016299 Riboflavin biosynthesis protein RibBA GO:0009231 KEGG: 00740+3.5.4.25+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CAK77_RS13670 17358897fcfe03b2991777379d33abf0 417 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 5 202 4.0E-71 T 06-07-2017 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CAK77_RS13670 17358897fcfe03b2991777379d33abf0 417 Gene3D G3DSA:3.90.870.10 2 214 7.1E-93 T 06-07-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain CAK77_RS13670 17358897fcfe03b2991777379d33abf0 417 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 2 206 36.898 T 06-07-2017 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CAK77_RS03745 0846fa56e8ebe64e7408c5f152a90b84 210 Pfam PF16925 Bacterial transcriptional repressor C-terminal 95 206 3.7E-45 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS03745 0846fa56e8ebe64e7408c5f152a90b84 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 29 69 5.5E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS03745 0846fa56e8ebe64e7408c5f152a90b84 210 SUPERFAMILY SSF48498 95 205 3.42E-26 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS03745 0846fa56e8ebe64e7408c5f152a90b84 210 SUPERFAMILY SSF46689 14 88 2.87E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS03745 0846fa56e8ebe64e7408c5f152a90b84 210 Gene3D G3DSA:1.10.10.60 15 72 3.1E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS03745 0846fa56e8ebe64e7408c5f152a90b84 210 Gene3D G3DSA:1.10.357.10 73 205 2.0E-25 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS08965 f8101cde69a7917a039bac375ee48af2 402 SUPERFAMILY SSF53901 270 376 3.6E-28 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS08965 f8101cde69a7917a039bac375ee48af2 402 SUPERFAMILY SSF53901 7 238 4.53E-48 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS08965 f8101cde69a7917a039bac375ee48af2 402 Pfam PF02803 Thiolase, C-terminal domain 273 376 3.8E-10 T 06-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CAK77_RS08965 f8101cde69a7917a039bac375ee48af2 402 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 82 100 - T 06-07-2017 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 CAK77_RS08965 f8101cde69a7917a039bac375ee48af2 402 Gene3D G3DSA:3.40.47.10 25 121 3.8E-27 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS08965 f8101cde69a7917a039bac375ee48af2 402 Gene3D G3DSA:3.40.47.10 209 231 3.8E-27 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS08965 f8101cde69a7917a039bac375ee48af2 402 Gene3D G3DSA:3.40.47.10 149 190 8.7E-25 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS08965 f8101cde69a7917a039bac375ee48af2 402 Gene3D G3DSA:3.40.47.10 255 394 8.7E-25 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS08965 f8101cde69a7917a039bac375ee48af2 402 PIRSF PIRSF000429 1 398 8.5E-70 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 CAK77_RS08965 f8101cde69a7917a039bac375ee48af2 402 Pfam PF00108 Thiolase, N-terminal domain 7 231 6.6E-22 T 06-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CAK77_RS08965 f8101cde69a7917a039bac375ee48af2 402 ProSitePatterns PS00737 Thiolases signature 2. 335 351 - T 06-07-2017 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CAK77_RS19995 940e1c51d363e65458b2e6a64aa56e31 306 PRINTS PR00151 Porphobilinogen deaminase signature 68 87 1.8E-24 T 06-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAK77_RS19995 940e1c51d363e65458b2e6a64aa56e31 306 PRINTS PR00151 Porphobilinogen deaminase signature 222 239 1.8E-24 T 06-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAK77_RS19995 940e1c51d363e65458b2e6a64aa56e31 306 PRINTS PR00151 Porphobilinogen deaminase signature 135 152 1.8E-24 T 06-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAK77_RS19995 940e1c51d363e65458b2e6a64aa56e31 306 PRINTS PR00151 Porphobilinogen deaminase signature 116 133 1.8E-24 T 06-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAK77_RS19995 940e1c51d363e65458b2e6a64aa56e31 306 Gene3D G3DSA:3.30.160.40 213 304 2.0E-22 T 06-07-2017 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAK77_RS19995 940e1c51d363e65458b2e6a64aa56e31 306 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 223 239 - T 06-07-2017 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAK77_RS19995 940e1c51d363e65458b2e6a64aa56e31 306 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 219 296 5.3E-19 T 06-07-2017 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAK77_RS19995 940e1c51d363e65458b2e6a64aa56e31 306 SUPERFAMILY SSF54782 212 304 1.96E-19 T 06-07-2017 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAK77_RS19995 940e1c51d363e65458b2e6a64aa56e31 306 Gene3D G3DSA:3.40.190.10 103 191 1.3E-32 T 06-07-2017 CAK77_RS19995 940e1c51d363e65458b2e6a64aa56e31 306 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 1 298 33.649 T 06-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAK77_RS19995 940e1c51d363e65458b2e6a64aa56e31 306 Gene3D G3DSA:3.40.190.10 2 102 7.7E-31 T 06-07-2017 CAK77_RS19995 940e1c51d363e65458b2e6a64aa56e31 306 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 2 203 1.7E-61 T 06-07-2017 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAK77_RS19995 940e1c51d363e65458b2e6a64aa56e31 306 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 2 296 2.6E-86 T 06-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAK77_RS19995 940e1c51d363e65458b2e6a64aa56e31 306 SUPERFAMILY SSF53850 2 210 3.64E-61 T 06-07-2017 CAK77_RS19995 940e1c51d363e65458b2e6a64aa56e31 306 PIRSF PIRSF001438 1 306 1.8E-102 T 06-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAK77_RS14615 5c45c6b33cf5ed6aef1423fbe137bd98 108 ProSitePatterns PS00768 Transthyretin signature 1. 7 22 - T 06-07-2017 IPR023418 Transthyretin, thyroxine binding site Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-975634|Reactome: R-HSA-977225 CAK77_RS14615 5c45c6b33cf5ed6aef1423fbe137bd98 108 TIGRFAM TIGR02962 hdxy_isourate: hydroxyisourate hydrolase 2 108 3.3E-34 T 06-07-2017 IPR014306 Hydroxyisourate hydrolase GO:0006144|GO:0033971 KEGG: 00230+3.5.2.17|MetaCyc: PWY-5691|MetaCyc: PWY-7394 CAK77_RS14615 5c45c6b33cf5ed6aef1423fbe137bd98 108 Gene3D G3DSA:2.60.40.180 3 108 9.9E-35 T 06-07-2017 IPR023416 Transthyretin/hydroxyisourate hydrolase, superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-975634|Reactome: R-HSA-977225 CAK77_RS14615 5c45c6b33cf5ed6aef1423fbe137bd98 108 Pfam PF00576 HIUase/Transthyretin family 4 107 1.3E-32 T 06-07-2017 IPR023416 Transthyretin/hydroxyisourate hydrolase, superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-975634|Reactome: R-HSA-977225 CAK77_RS14615 5c45c6b33cf5ed6aef1423fbe137bd98 108 PRINTS PR00189 Transthyretin signature 3 23 1.1E-7 T 06-07-2017 IPR000895 Transthyretin/hydroxyisourate hydrolase Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-975634|Reactome: R-HSA-977225 CAK77_RS14615 5c45c6b33cf5ed6aef1423fbe137bd98 108 PRINTS PR00189 Transthyretin signature 86 108 1.1E-7 T 06-07-2017 IPR000895 Transthyretin/hydroxyisourate hydrolase Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-975634|Reactome: R-HSA-977225 CAK77_RS14615 5c45c6b33cf5ed6aef1423fbe137bd98 108 SUPERFAMILY SSF49472 2 108 1.57E-35 T 06-07-2017 IPR023416 Transthyretin/hydroxyisourate hydrolase, superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-975634|Reactome: R-HSA-977225 CAK77_RS11405 cf3b4f8c590f719b6c79483d8a5b58e8 473 Gene3D G3DSA:1.20.200.10 113 380 3.0E-93 T 06-07-2017 CAK77_RS11405 cf3b4f8c590f719b6c79483d8a5b58e8 473 Pfam PF14698 Argininosuccinate lyase C-terminal 369 437 3.8E-21 T 06-07-2017 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CAK77_RS11405 cf3b4f8c590f719b6c79483d8a5b58e8 473 Gene3D G3DSA:1.10.40.30 381 437 5.2E-27 T 06-07-2017 CAK77_RS11405 cf3b4f8c590f719b6c79483d8a5b58e8 473 ProSitePatterns PS00163 Fumarate lyases signature. 281 290 - T 06-07-2017 IPR020557 Fumarate lyase, conserved site GO:0003824 CAK77_RS11405 cf3b4f8c590f719b6c79483d8a5b58e8 473 PRINTS PR00149 Fumarate lyase superfamily signature 153 171 3.6E-24 T 06-07-2017 IPR000362 Fumarate lyase family CAK77_RS11405 cf3b4f8c590f719b6c79483d8a5b58e8 473 PRINTS PR00149 Fumarate lyase superfamily signature 237 264 3.6E-24 T 06-07-2017 IPR000362 Fumarate lyase family CAK77_RS11405 cf3b4f8c590f719b6c79483d8a5b58e8 473 PRINTS PR00149 Fumarate lyase superfamily signature 281 297 3.6E-24 T 06-07-2017 IPR000362 Fumarate lyase family CAK77_RS11405 cf3b4f8c590f719b6c79483d8a5b58e8 473 PRINTS PR00149 Fumarate lyase superfamily signature 108 126 3.6E-24 T 06-07-2017 IPR000362 Fumarate lyase family CAK77_RS11405 cf3b4f8c590f719b6c79483d8a5b58e8 473 Pfam PF00206 Lyase 19 306 1.7E-60 T 06-07-2017 IPR022761 Fumarate lyase, N-terminal CAK77_RS11405 cf3b4f8c590f719b6c79483d8a5b58e8 473 SUPERFAMILY SSF48557 11 462 1.32E-130 T 06-07-2017 IPR008948 L-Aspartase-like GO:0003824 CAK77_RS11405 cf3b4f8c590f719b6c79483d8a5b58e8 473 TIGRFAM TIGR00838 argH: argininosuccinate lyase 8 455 2.2E-181 T 06-07-2017 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CAK77_RS11405 cf3b4f8c590f719b6c79483d8a5b58e8 473 PRINTS PR00145 Argininosuccinate lyase family signature 148 168 4.3E-52 T 06-07-2017 CAK77_RS11405 cf3b4f8c590f719b6c79483d8a5b58e8 473 PRINTS PR00145 Argininosuccinate lyase family signature 237 261 4.3E-52 T 06-07-2017 CAK77_RS11405 cf3b4f8c590f719b6c79483d8a5b58e8 473 PRINTS PR00145 Argininosuccinate lyase family signature 107 129 4.3E-52 T 06-07-2017 CAK77_RS11405 cf3b4f8c590f719b6c79483d8a5b58e8 473 PRINTS PR00145 Argininosuccinate lyase family signature 199 215 4.3E-52 T 06-07-2017 CAK77_RS11405 cf3b4f8c590f719b6c79483d8a5b58e8 473 PRINTS PR00145 Argininosuccinate lyase family signature 316 335 4.3E-52 T 06-07-2017 CAK77_RS11405 cf3b4f8c590f719b6c79483d8a5b58e8 473 PRINTS PR00145 Argininosuccinate lyase family signature 281 297 4.3E-52 T 06-07-2017 CAK77_RS11405 cf3b4f8c590f719b6c79483d8a5b58e8 473 Hamap MF_00006 Argininosuccinate lyase [argH]. 7 459 39.244 T 06-07-2017 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CAK77_RS11405 cf3b4f8c590f719b6c79483d8a5b58e8 473 Gene3D G3DSA:1.10.275.10 8 112 2.7E-32 T 06-07-2017 IPR024083 Fumarase/histidase, N-terminal CAK77_RS02185 4625ad62511878de4b52a9aac676030a 75 Gene3D G3DSA:1.10.260.40 47 74 8.3E-6 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK77_RS02185 4625ad62511878de4b52a9aac676030a 75 SUPERFAMILY SSF47413 46 74 2.05E-5 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK77_RS15990 690cc46debfefbb7e4e56c0d75be9e29 120 Hamap MF_00048 UPF0102 protein YraN [yraN]. 7 117 23.124 T 06-07-2017 IPR003509 Uncharacterised protein family UPF0102 CAK77_RS15990 690cc46debfefbb7e4e56c0d75be9e29 120 TIGRFAM TIGR00252 TIGR00252: TIGR00252 family protein 4 105 1.1E-20 T 06-07-2017 IPR003509 Uncharacterised protein family UPF0102 CAK77_RS15990 690cc46debfefbb7e4e56c0d75be9e29 120 Pfam PF02021 Uncharacterised protein family UPF0102 14 104 1.4E-31 T 06-07-2017 IPR003509 Uncharacterised protein family UPF0102 CAK77_RS15990 690cc46debfefbb7e4e56c0d75be9e29 120 Gene3D G3DSA:3.40.1350.10 14 119 9.8E-37 T 06-07-2017 IPR011856 tRNA endonuclease-like domain GO:0003676|GO:0004518 Reactome: R-HSA-6784531 CAK77_RS15990 690cc46debfefbb7e4e56c0d75be9e29 120 SUPERFAMILY SSF52980 14 105 4.11E-25 T 06-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CAK77_RS18490 29f1e76f1f7142a7d03e6618d0566409 215 SUPERFAMILY SSF46894 143 213 7.48E-22 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAK77_RS18490 29f1e76f1f7142a7d03e6618d0566409 215 Pfam PF00196 Bacterial regulatory proteins, luxR family 153 209 3.1E-17 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK77_RS18490 29f1e76f1f7142a7d03e6618d0566409 215 SMART SM00421 152 209 7.4E-23 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK77_RS18490 29f1e76f1f7142a7d03e6618d0566409 215 SUPERFAMILY SSF52172 1 134 3.42E-25 T 06-07-2017 IPR011006 CheY-like superfamily CAK77_RS18490 29f1e76f1f7142a7d03e6618d0566409 215 SMART SM00448 3 115 2.6E-18 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK77_RS18490 29f1e76f1f7142a7d03e6618d0566409 215 Gene3D G3DSA:1.10.10.10 121 214 5.7E-34 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS18490 29f1e76f1f7142a7d03e6618d0566409 215 Gene3D G3DSA:3.40.50.2300 1 120 1.8E-25 T 06-07-2017 CAK77_RS18490 29f1e76f1f7142a7d03e6618d0566409 215 ProSitePatterns PS00622 LuxR-type HTH domain signature. 169 196 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK77_RS18490 29f1e76f1f7142a7d03e6618d0566409 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 8.4E-14 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK77_RS18490 29f1e76f1f7142a7d03e6618d0566409 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 8.4E-14 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK77_RS18490 29f1e76f1f7142a7d03e6618d0566409 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 8.4E-14 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK77_RS18490 29f1e76f1f7142a7d03e6618d0566409 215 Pfam PF00072 Response regulator receiver domain 5 115 5.1E-16 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK77_RS15480 f89fe1265b8359c469af25dab44cafa7 240 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 16 76 1.8E-23 T 06-07-2017 IPR022687 DTXR-type HTH domain GO:0003677 CAK77_RS15480 f89fe1265b8359c469af25dab44cafa7 240 SUPERFAMILY SSF47979 79 152 2.49E-25 T 06-07-2017 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 CAK77_RS15480 f89fe1265b8359c469af25dab44cafa7 240 SUPERFAMILY SSF50037 165 237 4.27E-7 T 06-07-2017 IPR008988 Transcriptional repressor, C-terminal CAK77_RS15480 f89fe1265b8359c469af25dab44cafa7 240 SUPERFAMILY SSF46785 17 78 4.75E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS15480 f89fe1265b8359c469af25dab44cafa7 240 SMART SM00899 159 239 2.0E-12 T 06-07-2017 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CAK77_RS15480 f89fe1265b8359c469af25dab44cafa7 240 SMART SM00529 40 139 1.4E-41 T 06-07-2017 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 CAK77_RS15480 f89fe1265b8359c469af25dab44cafa7 240 Pfam PF04023 FeoA domain 159 237 9.5E-20 T 06-07-2017 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CAK77_RS15480 f89fe1265b8359c469af25dab44cafa7 240 Gene3D G3DSA:1.10.10.10 16 86 1.8E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS15480 f89fe1265b8359c469af25dab44cafa7 240 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 79 147 8.9E-29 T 06-07-2017 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 CAK77_RS15480 f89fe1265b8359c469af25dab44cafa7 240 Gene3D G3DSA:1.10.60.10 89 153 1.2E-30 T 06-07-2017 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 CAK77_RS12225 44fd3beef2ffd78ef6443701ec82703e 254 Gene3D G3DSA:3.60.21.10 2 221 2.5E-25 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAK77_RS12225 44fd3beef2ffd78ef6443701ec82703e 254 SUPERFAMILY SSF56300 2 224 1.49E-31 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAK77_RS12225 44fd3beef2ffd78ef6443701ec82703e 254 Pfam PF00149 Calcineurin-like phosphoesterase 2 205 1.4E-11 T 06-07-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 CAK77_RS12225 44fd3beef2ffd78ef6443701ec82703e 254 PIRSF PIRSF008292 1 235 1.3E-89 T 06-07-2017 IPR016538 Uncharacterised conserved protein UCP008292 CAK77_RS14880 4ef8f117818fc50a6d15d1b67ac0c9b2 638 SUPERFAMILY SSF52518 293 477 4.42E-55 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK77_RS14880 4ef8f117818fc50a6d15d1b67ac0c9b2 638 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 2 279 2.2E-106 T 06-07-2017 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CAK77_RS14880 4ef8f117818fc50a6d15d1b67ac0c9b2 638 Pfam PF02780 Transketolase, C-terminal domain 502 613 2.3E-24 T 06-07-2017 IPR033248 Transketolase, C-terminal domain CAK77_RS14880 4ef8f117818fc50a6d15d1b67ac0c9b2 638 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 1 622 42.092 T 06-07-2017 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CAK77_RS14880 4ef8f117818fc50a6d15d1b67ac0c9b2 638 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 5 621 1.2E-195 T 06-07-2017 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CAK77_RS14880 4ef8f117818fc50a6d15d1b67ac0c9b2 638 Pfam PF02779 Transketolase, pyrimidine binding domain 316 478 4.3E-38 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain CAK77_RS14880 4ef8f117818fc50a6d15d1b67ac0c9b2 638 ProSitePatterns PS00802 Transketolase signature 2. 421 437 - T 06-07-2017 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CAK77_RS14880 4ef8f117818fc50a6d15d1b67ac0c9b2 638 Gene3D G3DSA:3.40.50.970 298 479 4.3E-59 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK77_RS14880 4ef8f117818fc50a6d15d1b67ac0c9b2 638 Gene3D G3DSA:3.40.50.970 236 297 2.0E-46 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK77_RS14880 4ef8f117818fc50a6d15d1b67ac0c9b2 638 Gene3D G3DSA:3.40.50.970 3 188 2.0E-46 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK77_RS14880 4ef8f117818fc50a6d15d1b67ac0c9b2 638 SUPERFAMILY SSF52518 18 194 6.23E-67 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK77_RS14880 4ef8f117818fc50a6d15d1b67ac0c9b2 638 SUPERFAMILY SSF52518 239 362 6.23E-67 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK77_RS14880 4ef8f117818fc50a6d15d1b67ac0c9b2 638 Gene3D G3DSA:3.40.50.920 502 621 4.2E-27 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CAK77_RS14880 4ef8f117818fc50a6d15d1b67ac0c9b2 638 ProSitePatterns PS00801 Transketolase signature 1. 27 46 - T 06-07-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CAK77_RS14880 4ef8f117818fc50a6d15d1b67ac0c9b2 638 SUPERFAMILY SSF52922 502 621 2.49E-23 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CAK77_RS14880 4ef8f117818fc50a6d15d1b67ac0c9b2 638 SMART SM00861 315 479 7.1E-57 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain CAK77_RS18725 3944aa5e7d6f5e2ef310f1002f4a3b31 92 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 4 90 9.1E-19 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like CAK77_RS18725 3944aa5e7d6f5e2ef310f1002f4a3b31 92 SUPERFAMILY SSF140453 3 89 9.02E-18 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like CAK77_RS18725 3944aa5e7d6f5e2ef310f1002f4a3b31 92 Gene3D G3DSA:1.10.287.1060 4 91 3.0E-16 T 06-07-2017 CAK77_RS18725 3944aa5e7d6f5e2ef310f1002f4a3b31 92 Pfam PF06013 Proteins of 100 residues with WXG 7 88 6.0E-14 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like CAK77_RS09460 19a9170e3acb470f5bfdfe0bcf9e986a 502 SUPERFAMILY SSF53187 179 497 1.82E-108 T 06-07-2017 CAK77_RS09460 19a9170e3acb470f5bfdfe0bcf9e986a 502 Gene3D G3DSA:3.40.220.10 24 175 1.7E-23 T 06-07-2017 CAK77_RS09460 19a9170e3acb470f5bfdfe0bcf9e986a 502 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 346 353 - T 06-07-2017 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 CAK77_RS09460 19a9170e3acb470f5bfdfe0bcf9e986a 502 Gene3D G3DSA:3.40.630.10 176 498 8.0E-128 T 06-07-2017 CAK77_RS09460 19a9170e3acb470f5bfdfe0bcf9e986a 502 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 184 491 1.9E-111 T 06-07-2017 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 CAK77_RS09460 19a9170e3acb470f5bfdfe0bcf9e986a 502 PRINTS PR00481 Cytosol aminopeptidase signature 261 278 9.8E-49 T 06-07-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CAK77_RS09460 19a9170e3acb470f5bfdfe0bcf9e986a 502 PRINTS PR00481 Cytosol aminopeptidase signature 320 341 9.8E-49 T 06-07-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CAK77_RS09460 19a9170e3acb470f5bfdfe0bcf9e986a 502 PRINTS PR00481 Cytosol aminopeptidase signature 342 362 9.8E-49 T 06-07-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CAK77_RS09460 19a9170e3acb470f5bfdfe0bcf9e986a 502 PRINTS PR00481 Cytosol aminopeptidase signature 283 304 9.8E-49 T 06-07-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CAK77_RS09460 19a9170e3acb470f5bfdfe0bcf9e986a 502 PRINTS PR00481 Cytosol aminopeptidase signature 370 385 9.8E-49 T 06-07-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CAK77_RS09460 19a9170e3acb470f5bfdfe0bcf9e986a 502 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 10 500 34.177 T 06-07-2017 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 CAK77_RS09460 19a9170e3acb470f5bfdfe0bcf9e986a 502 SUPERFAMILY SSF52949 24 163 4.59E-20 T 06-07-2017 CAK77_RS09460 19a9170e3acb470f5bfdfe0bcf9e986a 502 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 40 146 1.4E-16 T 06-07-2017 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 CAK77_RS21070 a67508576126e5ba82416392165458ff 646 Gene3D G3DSA:3.10.450.40 3 97 3.5E-26 T 06-07-2017 CAK77_RS21070 a67508576126e5ba82416392165458ff 646 Pfam PF02727 Copper amine oxidase, N2 domain 6 91 2.1E-12 T 06-07-2017 IPR015800 Copper amine oxidase, N2-terminal GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 KEGG: 00260+1.4.3.21|KEGG: 00350+1.4.3.21|KEGG: 00360+1.4.3.21|KEGG: 00410+1.4.3.21|KEGG: 00950+1.4.3.21|KEGG: 00960+1.4.3.21|MetaCyc: PWY-5751|Reactome: R-HSA-211945 CAK77_RS21070 a67508576126e5ba82416392165458ff 646 Pfam PF02728 Copper amine oxidase, N3 domain 97 194 1.0E-13 T 06-07-2017 IPR015802 Copper amine oxidase, N3-terminal GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 KEGG: 00260+1.4.3.21|KEGG: 00350+1.4.3.21|KEGG: 00360+1.4.3.21|KEGG: 00410+1.4.3.21|KEGG: 00950+1.4.3.21|KEGG: 00960+1.4.3.21|MetaCyc: PWY-5751|Reactome: R-HSA-211945 CAK77_RS21070 a67508576126e5ba82416392165458ff 646 Gene3D G3DSA:2.70.98.20 191 643 1.3E-172 T 06-07-2017 IPR015798 Copper amine oxidase, C-terminal GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 CAK77_RS21070 a67508576126e5ba82416392165458ff 646 SUPERFAMILY SSF49998 220 632 2.75E-152 T 06-07-2017 IPR015798 Copper amine oxidase, C-terminal GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 CAK77_RS21070 a67508576126e5ba82416392165458ff 646 Pfam PF01179 Copper amine oxidase, enzyme domain 226 631 5.6E-154 T 06-07-2017 IPR015798 Copper amine oxidase, C-terminal GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 CAK77_RS21070 a67508576126e5ba82416392165458ff 646 Gene3D G3DSA:3.10.450.40 100 190 1.7E-27 T 06-07-2017 CAK77_RS21070 a67508576126e5ba82416392165458ff 646 SUPERFAMILY SSF54416 3 97 4.09E-24 T 06-07-2017 IPR016182 Copper amine oxidase, N-terminal GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 CAK77_RS21070 a67508576126e5ba82416392165458ff 646 SUPERFAMILY SSF54416 96 211 9.16E-29 T 06-07-2017 IPR016182 Copper amine oxidase, N-terminal GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 CAK77_RS10880 0bb3901dbbeb6a53798c2d4b7e325c7b 1343 Gene3D G3DSA:3.40.50.300 820 1017 2.0E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS10880 0bb3901dbbeb6a53798c2d4b7e325c7b 1343 Gene3D G3DSA:3.40.50.300 452 684 3.7E-22 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS10880 0bb3901dbbeb6a53798c2d4b7e325c7b 1343 Gene3D G3DSA:3.40.50.300 1112 1262 9.7E-7 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS10880 0bb3901dbbeb6a53798c2d4b7e325c7b 1343 Pfam PF01580 FtsK/SpoIIIE family 803 1052 9.2E-63 T 06-07-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CAK77_RS10880 0bb3901dbbeb6a53798c2d4b7e325c7b 1343 Pfam PF01580 FtsK/SpoIIIE family 451 644 7.0E-19 T 06-07-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CAK77_RS10880 0bb3901dbbeb6a53798c2d4b7e325c7b 1343 Pfam PF05729 NACHT domain 1117 1268 6.1E-7 T 06-07-2017 CAK77_RS10880 0bb3901dbbeb6a53798c2d4b7e325c7b 1343 TIGRFAM TIGR03925 T7SS_EccC_b: type VII secretion protein EccCb 762 1326 1.7E-171 T 06-07-2017 IPR023837 EccCb-like, Actinobacteria CAK77_RS10880 0bb3901dbbeb6a53798c2d4b7e325c7b 1343 SUPERFAMILY SSF52540 938 1019 3.03E-13 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS10880 0bb3901dbbeb6a53798c2d4b7e325c7b 1343 SUPERFAMILY SSF52540 828 910 3.03E-13 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS10880 0bb3901dbbeb6a53798c2d4b7e325c7b 1343 SUPERFAMILY SSF52540 444 711 1.08E-26 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS10880 0bb3901dbbeb6a53798c2d4b7e325c7b 1343 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 1117 1130 - T 06-07-2017 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 CAK77_RS10880 0bb3901dbbeb6a53798c2d4b7e325c7b 1343 SMART SM00382 830 1013 0.011 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS10880 0bb3901dbbeb6a53798c2d4b7e325c7b 1343 SMART SM00382 1113 1289 5.1E-5 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS10880 0bb3901dbbeb6a53798c2d4b7e325c7b 1343 SMART SM00382 480 666 0.45 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS10880 0bb3901dbbeb6a53798c2d4b7e325c7b 1343 SUPERFAMILY SSF52540 1087 1260 1.1E-9 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS10880 0bb3901dbbeb6a53798c2d4b7e325c7b 1343 TIGRFAM TIGR03924 T7SS_EccC_a: type VII secretion protein EccCa 24 714 5.4E-225 T 06-07-2017 IPR023836 EccCa-like, Actinobacteria CAK77_RS12135 99dcb3e0d37ff2ec809ec1b344fa65a5 382 Gene3D G3DSA:2.40.110.10 122 222 7.8E-18 T 06-07-2017 CAK77_RS12135 99dcb3e0d37ff2ec809ec1b344fa65a5 382 Gene3D G3DSA:1.10.540.10 1 98 5.6E-12 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS12135 99dcb3e0d37ff2ec809ec1b344fa65a5 382 Gene3D G3DSA:1.20.140.10 223 362 1.8E-30 T 06-07-2017 CAK77_RS12135 99dcb3e0d37ff2ec809ec1b344fa65a5 382 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 216 2.6E-15 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAK77_RS12135 99dcb3e0d37ff2ec809ec1b344fa65a5 382 SUPERFAMILY SSF47203 233 373 9.02E-31 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS12135 99dcb3e0d37ff2ec809ec1b344fa65a5 382 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 117 2.3E-8 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS12135 99dcb3e0d37ff2ec809ec1b344fa65a5 382 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 234 367 2.9E-22 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS12135 99dcb3e0d37ff2ec809ec1b344fa65a5 382 SUPERFAMILY SSF56645 1 230 9.95E-40 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK77_RS10700 a0f88aac6fab06ec7cf77f307ff50b02 242 TIGRFAM TIGR00715 precor6x_red: precorrin-6x reductase 1 236 9.4E-58 T 06-07-2017 IPR003723 Precorrin-6x reductase GO:0009236|GO:0016994|GO:0055114 CAK77_RS10700 a0f88aac6fab06ec7cf77f307ff50b02 242 Gene3D G3DSA:3.40.50.2300 175 226 1.6E-4 T 06-07-2017 CAK77_RS10700 a0f88aac6fab06ec7cf77f307ff50b02 242 Pfam PF02571 Precorrin-6x reductase CbiJ/CobK 1 234 1.3E-67 T 06-07-2017 IPR003723 Precorrin-6x reductase GO:0009236|GO:0016994|GO:0055114 CAK77_RS12490 5de063dbe656045239f31bbc310b9896 249 SUPERFAMILY SSF46894 136 206 2.18E-18 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAK77_RS12490 5de063dbe656045239f31bbc310b9896 249 ProSitePatterns PS00622 LuxR-type HTH domain signature. 163 190 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK77_RS12490 5de063dbe656045239f31bbc310b9896 249 SUPERFAMILY SSF52172 2 130 4.7E-29 T 06-07-2017 IPR011006 CheY-like superfamily CAK77_RS12490 5de063dbe656045239f31bbc310b9896 249 SMART SM00421 146 203 2.3E-22 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK77_RS12490 5de063dbe656045239f31bbc310b9896 249 Gene3D G3DSA:1.10.10.10 147 205 1.7E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS12490 5de063dbe656045239f31bbc310b9896 249 Pfam PF00072 Response regulator receiver domain 4 116 2.7E-23 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK77_RS12490 5de063dbe656045239f31bbc310b9896 249 SMART SM00448 2 115 2.1E-24 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK77_RS12490 5de063dbe656045239f31bbc310b9896 249 Pfam PF00196 Bacterial regulatory proteins, luxR family 148 203 5.5E-17 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK77_RS12490 5de063dbe656045239f31bbc310b9896 249 Gene3D G3DSA:3.40.50.2300 2 146 6.5E-33 T 06-07-2017 CAK77_RS12490 5de063dbe656045239f31bbc310b9896 249 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 149 163 2.6E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK77_RS12490 5de063dbe656045239f31bbc310b9896 249 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 191 2.6E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK77_RS12490 5de063dbe656045239f31bbc310b9896 249 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 179 2.6E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK77_RS14030 307577c060c1acacfe7686f8d5366401 335 Pfam PF04055 Radical SAM superfamily 62 239 4.6E-10 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 CAK77_RS14030 307577c060c1acacfe7686f8d5366401 335 Gene3D G3DSA:3.20.20.70 56 295 1.3E-9 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK77_RS14030 307577c060c1acacfe7686f8d5366401 335 SUPERFAMILY SSF102114 57 271 2.09E-10 T 06-07-2017 CAK77_RS14030 307577c060c1acacfe7686f8d5366401 335 SMART SM00729 57 284 0.0041 T 06-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CAK77_RS14840 7e69d306761bfbdcfec7a9f6d5827045 391 Pfam PF07690 Major Facilitator Superfamily 9 316 1.7E-25 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK77_RS14840 7e69d306761bfbdcfec7a9f6d5827045 391 Gene3D G3DSA:1.20.1250.20 200 380 4.0E-8 T 06-07-2017 CAK77_RS14840 7e69d306761bfbdcfec7a9f6d5827045 391 Gene3D G3DSA:1.20.1250.20 6 178 7.6E-19 T 06-07-2017 CAK77_RS14840 7e69d306761bfbdcfec7a9f6d5827045 391 SUPERFAMILY SSF103473 5 377 1.44E-43 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK77_RS13225 66b2c3b011c11d31092d9adad109df2b 305 Pfam PF01479 S4 domain 15 57 6.6E-5 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 CAK77_RS13225 66b2c3b011c11d31092d9adad109df2b 305 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 135 149 - T 06-07-2017 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAK77_RS13225 66b2c3b011c11d31092d9adad109df2b 305 SUPERFAMILY SSF55174 14 66 2.22E-6 T 06-07-2017 CAK77_RS13225 66b2c3b011c11d31092d9adad109df2b 305 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 13 305 1.8E-85 T 06-07-2017 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAK77_RS13225 66b2c3b011c11d31092d9adad109df2b 305 SMART SM00363 15 76 2.0E-4 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 CAK77_RS13225 66b2c3b011c11d31092d9adad109df2b 305 Gene3D G3DSA:3.10.290.10 14 56 7.8E-7 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 CAK77_RS13225 66b2c3b011c11d31092d9adad109df2b 305 SUPERFAMILY SSF55120 76 304 2.56E-66 T 06-07-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAK77_RS13225 66b2c3b011c11d31092d9adad109df2b 305 Pfam PF00849 RNA pseudouridylate synthase 89 243 1.0E-30 T 06-07-2017 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAK77_RS14655 2db1654c78db57ad8434dacf67674afe 453 Gene3D G3DSA:1.10.3860.10 23 427 1.4E-106 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CAK77_RS14655 2db1654c78db57ad8434dacf67674afe 453 SUPERFAMILY SSF118215 25 423 2.22E-109 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CAK77_RS14655 2db1654c78db57ad8434dacf67674afe 453 Pfam PF00375 Sodium:dicarboxylate symporter family 25 422 1.2E-109 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CAK77_RS14655 2db1654c78db57ad8434dacf67674afe 453 PRINTS PR00173 Glutamate-aspartate symporter signature 90 115 2.6E-24 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CAK77_RS14655 2db1654c78db57ad8434dacf67674afe 453 PRINTS PR00173 Glutamate-aspartate symporter signature 23 43 2.6E-24 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CAK77_RS14655 2db1654c78db57ad8434dacf67674afe 453 PRINTS PR00173 Glutamate-aspartate symporter signature 211 230 2.6E-24 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CAK77_RS14655 2db1654c78db57ad8434dacf67674afe 453 PRINTS PR00173 Glutamate-aspartate symporter signature 311 337 2.6E-24 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CAK77_RS14655 2db1654c78db57ad8434dacf67674afe 453 PRINTS PR00173 Glutamate-aspartate symporter signature 163 185 2.6E-24 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CAK77_RS14655 2db1654c78db57ad8434dacf67674afe 453 PRINTS PR00173 Glutamate-aspartate symporter signature 346 365 2.6E-24 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CAK77_RS14655 2db1654c78db57ad8434dacf67674afe 453 ProSitePatterns PS00714 Sodium:dicarboxylate symporter family signature 2. 314 337 - T 06-07-2017 IPR018107 Sodium:dicarboxylate symporter, conserved site CAK77_RS06900 80cab95237dd0ea141e371911769d7ed 364 Gene3D G3DSA:3.30.460.20 17 175 7.7E-43 T 06-07-2017 CAK77_RS06900 80cab95237dd0ea141e371911769d7ed 364 SUPERFAMILY SSF144083 299 361 1.44E-16 T 06-07-2017 CAK77_RS06900 80cab95237dd0ea141e371911769d7ed 364 SUPERFAMILY SSF143865 28 293 6.02E-68 T 06-07-2017 CAK77_RS06900 80cab95237dd0ea141e371911769d7ed 364 Gene3D G3DSA:1.20.58.340 176 285 4.1E-36 T 06-07-2017 CAK77_RS06900 80cab95237dd0ea141e371911769d7ed 364 Pfam PF01544 CorA-like Mg2+ transporter protein 66 360 4.3E-62 T 06-07-2017 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 CAK77_RS06900 80cab95237dd0ea141e371911769d7ed 364 TIGRFAM TIGR00383 corA: magnesium and cobalt transport protein CorA 65 364 2.3E-61 T 06-07-2017 IPR004488 Magnesium/cobalt transport protein CorA GO:0006824|GO:0015087|GO:0015095|GO:0015693|GO:0016020 CAK77_RS06900 80cab95237dd0ea141e371911769d7ed 364 Gene3D G3DSA:1.20.58.340 288 364 9.1E-23 T 06-07-2017 CAK77_RS13830 645065d392fec0935c063a251bfe9d6b 391 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 15 145 9.9E-49 T 06-07-2017 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAK77_RS13830 645065d392fec0935c063a251bfe9d6b 391 PRINTS PR00096 Glutamine amidotransferase superfamily signature 356 369 2.2E-11 T 06-07-2017 CAK77_RS13830 645065d392fec0935c063a251bfe9d6b 391 PRINTS PR00096 Glutamine amidotransferase superfamily signature 265 276 2.2E-11 T 06-07-2017 CAK77_RS13830 645065d392fec0935c063a251bfe9d6b 391 PRINTS PR00096 Glutamine amidotransferase superfamily signature 237 246 2.2E-11 T 06-07-2017 CAK77_RS13830 645065d392fec0935c063a251bfe9d6b 391 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 195 209 1.2E-32 T 06-07-2017 CAK77_RS13830 645065d392fec0935c063a251bfe9d6b 391 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 265 281 1.2E-32 T 06-07-2017 CAK77_RS13830 645065d392fec0935c063a251bfe9d6b 391 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 282 299 1.2E-32 T 06-07-2017 CAK77_RS13830 645065d392fec0935c063a251bfe9d6b 391 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 307 318 1.2E-32 T 06-07-2017 CAK77_RS13830 645065d392fec0935c063a251bfe9d6b 391 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 234 248 1.2E-32 T 06-07-2017 CAK77_RS13830 645065d392fec0935c063a251bfe9d6b 391 Gene3D G3DSA:3.40.50.880 170 382 8.3E-63 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAK77_RS13830 645065d392fec0935c063a251bfe9d6b 391 PRINTS PR00097 Anthranilate synthase component II signature 356 369 6.5E-6 T 06-07-2017 CAK77_RS13830 645065d392fec0935c063a251bfe9d6b 391 PRINTS PR00097 Anthranilate synthase component II signature 237 246 6.5E-6 T 06-07-2017 CAK77_RS13830 645065d392fec0935c063a251bfe9d6b 391 PRINTS PR00097 Anthranilate synthase component II signature 265 276 6.5E-6 T 06-07-2017 CAK77_RS13830 645065d392fec0935c063a251bfe9d6b 391 SUPERFAMILY SSF52317 171 381 4.13E-51 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAK77_RS13830 645065d392fec0935c063a251bfe9d6b 391 Pfam PF00117 Glutamine amidotransferase class-I 199 378 4.1E-39 T 06-07-2017 IPR017926 Glutamine amidotransferase CAK77_RS13830 645065d392fec0935c063a251bfe9d6b 391 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 16 381 1.8E-132 T 06-07-2017 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAK77_RS13830 645065d392fec0935c063a251bfe9d6b 391 SUPERFAMILY SSF52021 15 154 6.54E-51 T 06-07-2017 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAK77_RS13830 645065d392fec0935c063a251bfe9d6b 391 Gene3D G3DSA:3.50.30.20 15 151 8.1E-54 T 06-07-2017 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAK77_RS13830 645065d392fec0935c063a251bfe9d6b 391 SMART SM01097 14 146 2.8E-79 T 06-07-2017 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAK77_RS13830 645065d392fec0935c063a251bfe9d6b 391 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 14 385 44.188 T 06-07-2017 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAK77_RS19835 529ca90fd73fbdecba6c0c339684b99b 73 Pfam PF08281 Sigma-70, region 4 44 73 4.2E-6 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS19835 529ca90fd73fbdecba6c0c339684b99b 73 Gene3D G3DSA:1.10.10.10 45 73 1.5E-5 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS19835 529ca90fd73fbdecba6c0c339684b99b 73 SUPERFAMILY SSF88659 44 73 3.4E-6 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS19815 b35c2f6ef977b72b798cbaa46fcaff43 257 TIGRFAM TIGR01694 MTAP: methylthioadenosine phosphorylase 1 233 3.1E-87 T 06-07-2017 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112 CAK77_RS19815 b35c2f6ef977b72b798cbaa46fcaff43 257 Hamap MF_01963 S-methyl-5'-thioadenosine phosphorylase [mtnP]. 1 255 36.293 T 06-07-2017 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112 CAK77_RS19815 b35c2f6ef977b72b798cbaa46fcaff43 257 Gene3D G3DSA:3.40.50.1580 2 246 6.4E-72 T 06-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CAK77_RS19815 b35c2f6ef977b72b798cbaa46fcaff43 257 Pfam PF01048 Phosphorylase superfamily 2 206 1.1E-35 T 06-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CAK77_RS19815 b35c2f6ef977b72b798cbaa46fcaff43 257 SUPERFAMILY SSF53167 1 250 1.19E-72 T 06-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CAK77_RS04995 ea2ebec7b776e87bc96fe137d5137590 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 37 47 1.8E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK77_RS04995 ea2ebec7b776e87bc96fe137d5137590 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 26 37 1.8E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK77_RS04995 ea2ebec7b776e87bc96fe137d5137590 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 47 58 1.8E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK77_RS04995 ea2ebec7b776e87bc96fe137d5137590 297 SUPERFAMILY SSF53850 99 294 6.79E-20 T 06-07-2017 CAK77_RS04995 ea2ebec7b776e87bc96fe137d5137590 297 SUPERFAMILY SSF46785 9 92 2.36E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS04995 ea2ebec7b776e87bc96fe137d5137590 297 Gene3D G3DSA:3.40.190.10 108 179 4.3E-16 T 06-07-2017 CAK77_RS04995 ea2ebec7b776e87bc96fe137d5137590 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 70 6.7E-20 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK77_RS04995 ea2ebec7b776e87bc96fe137d5137590 297 Gene3D G3DSA:1.10.10.10 9 94 3.3E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS04995 ea2ebec7b776e87bc96fe137d5137590 297 Pfam PF03466 LysR substrate binding domain 101 292 1.7E-20 T 06-07-2017 IPR005119 LysR, substrate-binding CAK77_RS04995 ea2ebec7b776e87bc96fe137d5137590 297 Gene3D G3DSA:3.40.190.10 180 264 6.7E-11 T 06-07-2017 CAK77_RS16430 1305a58e3c7e13218411f00593796fd9 496 Hamap MF_00022_B Glutamate--tRNA ligase [gltX]. 6 483 30.968 T 06-07-2017 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CAK77_RS16430 1305a58e3c7e13218411f00593796fd9 496 SUPERFAMILY SSF52374 5 318 6.44E-99 T 06-07-2017 CAK77_RS16430 1305a58e3c7e13218411f00593796fd9 496 Gene3D G3DSA:1.10.10.350 387 482 1.9E-19 T 06-07-2017 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CAK77_RS16430 1305a58e3c7e13218411f00593796fd9 496 PRINTS PR00987 Glutamyl-tRNA synthetase signature 9 21 3.9E-22 T 06-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CAK77_RS16430 1305a58e3c7e13218411f00593796fd9 496 PRINTS PR00987 Glutamyl-tRNA synthetase signature 38 51 3.9E-22 T 06-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CAK77_RS16430 1305a58e3c7e13218411f00593796fd9 496 PRINTS PR00987 Glutamyl-tRNA synthetase signature 23 34 3.9E-22 T 06-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CAK77_RS16430 1305a58e3c7e13218411f00593796fd9 496 PRINTS PR00987 Glutamyl-tRNA synthetase signature 193 203 3.9E-22 T 06-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CAK77_RS16430 1305a58e3c7e13218411f00593796fd9 496 PRINTS PR00987 Glutamyl-tRNA synthetase signature 209 217 3.9E-22 T 06-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CAK77_RS16430 1305a58e3c7e13218411f00593796fd9 496 Gene3D G3DSA:3.40.50.620 5 70 3.3E-42 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS16430 1305a58e3c7e13218411f00593796fd9 496 Gene3D G3DSA:3.40.50.620 195 249 3.3E-42 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS16430 1305a58e3c7e13218411f00593796fd9 496 SUPERFAMILY SSF48163 319 482 1.31E-34 T 06-07-2017 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CAK77_RS16430 1305a58e3c7e13218411f00593796fd9 496 Gene3D G3DSA:3.90.800.10 71 193 2.5E-34 T 06-07-2017 CAK77_RS16430 1305a58e3c7e13218411f00593796fd9 496 Gene3D G3DSA:1.10.1160.10 252 334 1.9E-28 T 06-07-2017 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 CAK77_RS16430 1305a58e3c7e13218411f00593796fd9 496 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 5 480 5.2E-128 T 06-07-2017 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CAK77_RS16430 1305a58e3c7e13218411f00593796fd9 496 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 5 322 5.0E-78 T 06-07-2017 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 CAK77_RS19500 b1fbde844e49a9ed954889fbd39155c1 330 SUPERFAMILY SSF55469 215 327 3.87E-16 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CAK77_RS19500 b1fbde844e49a9ed954889fbd39155c1 330 SUPERFAMILY SSF55469 5 71 3.87E-16 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CAK77_RS19500 b1fbde844e49a9ed954889fbd39155c1 330 Gene3D G3DSA:3.40.109.10 213 328 9.7E-28 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CAK77_RS19500 b1fbde844e49a9ed954889fbd39155c1 330 Gene3D G3DSA:3.40.109.10 6 120 9.7E-28 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CAK77_RS19500 b1fbde844e49a9ed954889fbd39155c1 330 SUPERFAMILY SSF55469 9 133 1.2E-7 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CAK77_RS15200 3fd6e18e863e8fdeeb402b4ce74d85ed 286 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 65 162 1.9E-16 T 06-07-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CAK77_RS15200 3fd6e18e863e8fdeeb402b4ce74d85ed 286 SUPERFAMILY SSF161098 64 253 6.8E-37 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS15200 3fd6e18e863e8fdeeb402b4ce74d85ed 286 Gene3D G3DSA:1.10.3720.10 63 268 1.8E-43 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS15200 3fd6e18e863e8fdeeb402b4ce74d85ed 286 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 84 268 5.0E-23 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS20440 3a56b7fc584f71ee42651e614640b65c 146 SUPERFAMILY SSF53955 33 107 3.38E-31 T 06-07-2017 IPR023346 Lysozyme-like domain CAK77_RS20440 3a56b7fc584f71ee42651e614640b65c 146 Pfam PF06737 Transglycosylase-like domain 34 106 2.5E-34 T 06-07-2017 IPR010618 Transglycosylase-like CAK77_RS20440 3a56b7fc584f71ee42651e614640b65c 146 Gene3D G3DSA:1.10.530.10 19 108 4.4E-40 T 06-07-2017 CAK77_RS12270 5863a777e0370eb3cd9e8d16e226d709 226 Gene3D G3DSA:1.10.10.10 149 199 2.3E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS12270 5863a777e0370eb3cd9e8d16e226d709 226 SUPERFAMILY SSF55785 37 129 1.73E-12 T 06-07-2017 IPR000014 PAS domain CAK77_RS12270 5863a777e0370eb3cd9e8d16e226d709 226 Pfam PF08447 PAS fold 38 124 1.3E-11 T 06-07-2017 IPR013655 PAS fold-3 GO:0005515 CAK77_RS12270 5863a777e0370eb3cd9e8d16e226d709 226 Pfam PF03861 ANTAR domain 149 195 1.1E-16 T 06-07-2017 IPR005561 ANTAR domain GO:0003723 CAK77_RS12270 5863a777e0370eb3cd9e8d16e226d709 226 SMART SM01012 140 195 3.6E-16 T 06-07-2017 IPR005561 ANTAR domain GO:0003723 CAK77_RS12270 5863a777e0370eb3cd9e8d16e226d709 226 SUPERFAMILY SSF52172 146 195 5.47E-5 T 06-07-2017 IPR011006 CheY-like superfamily CAK77_RS12270 5863a777e0370eb3cd9e8d16e226d709 226 Gene3D G3DSA:3.30.450.20 25 139 2.9E-14 T 06-07-2017 CAK77_RS03155 899e8539be9f6a26f4278a5b8cab4011 162 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 54 161 5.0E-34 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CAK77_RS03155 899e8539be9f6a26f4278a5b8cab4011 162 Pfam PF04075 Domain of unknown function (DUF385) 29 162 3.7E-41 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CAK77_RS04630 f61e2bed8b5007eb5b6b192ff6a95d91 326 Pfam PF12833 Helix-turn-helix domain 238 316 6.6E-21 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK77_RS04630 f61e2bed8b5007eb5b6b192ff6a95d91 326 Gene3D G3DSA:1.10.10.60 271 320 3.6E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS04630 f61e2bed8b5007eb5b6b192ff6a95d91 326 SMART SM00342 232 315 1.3E-24 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK77_RS04630 f61e2bed8b5007eb5b6b192ff6a95d91 326 Gene3D G3DSA:3.40.50.880 5 223 4.9E-54 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAK77_RS04630 f61e2bed8b5007eb5b6b192ff6a95d91 326 SUPERFAMILY SSF46689 268 319 2.24E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS04630 f61e2bed8b5007eb5b6b192ff6a95d91 326 SUPERFAMILY SSF46689 218 265 3.36E-7 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS04630 f61e2bed8b5007eb5b6b192ff6a95d91 326 Pfam PF01965 DJ-1/PfpI family 4 177 1.7E-23 T 06-07-2017 IPR002818 DJ-1/PfpI CAK77_RS04630 f61e2bed8b5007eb5b6b192ff6a95d91 326 Gene3D G3DSA:1.10.10.60 224 270 4.5E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS04630 f61e2bed8b5007eb5b6b192ff6a95d91 326 SUPERFAMILY SSF52317 4 197 3.48E-48 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAK77_RS12010 ae9e62badab61c8bb343e2720afe6e10 135 SUPERFAMILY SSF46785 3 132 2.83E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS12010 ae9e62badab61c8bb343e2720afe6e10 135 Pfam PF01047 MarR family 26 82 2.0E-11 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK77_RS12010 ae9e62badab61c8bb343e2720afe6e10 135 Gene3D G3DSA:1.10.10.10 3 132 1.7E-31 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS12010 ae9e62badab61c8bb343e2720afe6e10 135 PRINTS PR00598 Bacterial regulatory protein MarR family signature 78 94 4.2E-7 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK77_RS12010 ae9e62badab61c8bb343e2720afe6e10 135 PRINTS PR00598 Bacterial regulatory protein MarR family signature 42 58 4.2E-7 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK77_RS12010 ae9e62badab61c8bb343e2720afe6e10 135 PRINTS PR00598 Bacterial regulatory protein MarR family signature 108 128 4.2E-7 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK77_RS12010 ae9e62badab61c8bb343e2720afe6e10 135 PRINTS PR00598 Bacterial regulatory protein MarR family signature 59 74 4.2E-7 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK77_RS12010 ae9e62badab61c8bb343e2720afe6e10 135 SMART SM00347 18 118 1.4E-18 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK77_RS15760 aa223e2082b028dd7086d4bcb04f974e 605 Pfam PF00905 Penicillin binding protein transpeptidase domain 328 587 2.6E-37 T 06-07-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CAK77_RS15760 aa223e2082b028dd7086d4bcb04f974e 605 SUPERFAMILY SSF56601 308 595 3.76E-59 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK77_RS15760 aa223e2082b028dd7086d4bcb04f974e 605 Pfam PF05223 NTF2-like N-terminal transpeptidase domain 30 137 3.0E-16 T 06-07-2017 IPR007887 NTF2-like N-terminal transpeptidase GO:0046677 CAK77_RS15760 aa223e2082b028dd7086d4bcb04f974e 605 Gene3D G3DSA:3.40.710.10 307 598 1.5E-58 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK77_RS07360 d09390a1866564fd3075d531d01e8948 395 Gene3D G3DSA:3.40.47.10 280 394 2.8E-55 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS07360 d09390a1866564fd3075d531d01e8948 395 Gene3D G3DSA:3.40.47.10 145 196 2.8E-55 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS07360 d09390a1866564fd3075d531d01e8948 395 SUPERFAMILY SSF53901 275 393 3.03E-37 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS07360 d09390a1866564fd3075d531d01e8948 395 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 9 393 1.7E-134 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 CAK77_RS07360 d09390a1866564fd3075d531d01e8948 395 PIRSF PIRSF000429 1 395 6.5E-116 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 CAK77_RS07360 d09390a1866564fd3075d531d01e8948 395 ProSitePatterns PS00737 Thiolases signature 2. 342 358 - T 06-07-2017 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CAK77_RS07360 d09390a1866564fd3075d531d01e8948 395 Pfam PF02803 Thiolase, C-terminal domain 274 394 8.4E-45 T 06-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CAK77_RS07360 d09390a1866564fd3075d531d01e8948 395 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 87 105 - T 06-07-2017 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 CAK77_RS07360 d09390a1866564fd3075d531d01e8948 395 ProSitePatterns PS00099 Thiolases active site. 377 390 - T 06-07-2017 IPR020610 Thiolase, active site GO:0008152|GO:0016747 CAK77_RS07360 d09390a1866564fd3075d531d01e8948 395 SUPERFAMILY SSF53901 8 273 1.2E-80 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS07360 d09390a1866564fd3075d531d01e8948 395 Gene3D G3DSA:3.40.47.10 8 126 6.1E-69 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS07360 d09390a1866564fd3075d531d01e8948 395 Gene3D G3DSA:3.40.47.10 197 279 6.1E-69 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS07360 d09390a1866564fd3075d531d01e8948 395 Pfam PF00108 Thiolase, N-terminal domain 8 266 5.3E-94 T 06-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CAK77_RS24350 d355a26b305108fc4b2eef8d8ed7d899 330 SUPERFAMILY SSF109709 150 259 2.35E-30 T 06-07-2017 CAK77_RS24350 d355a26b305108fc4b2eef8d8ed7d899 330 SUPERFAMILY SSF110849 59 161 3.14E-31 T 06-07-2017 IPR003115 ParB/Sulfiredoxin CAK77_RS24350 d355a26b305108fc4b2eef8d8ed7d899 330 Gene3D G3DSA:3.90.1530.10 64 164 3.7E-40 T 06-07-2017 CAK77_RS24350 d355a26b305108fc4b2eef8d8ed7d899 330 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 65 244 3.2E-63 T 06-07-2017 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 CAK77_RS24350 d355a26b305108fc4b2eef8d8ed7d899 330 Pfam PF02195 ParB-like nuclease domain 69 158 1.8E-25 T 06-07-2017 IPR003115 ParB/Sulfiredoxin CAK77_RS24350 d355a26b305108fc4b2eef8d8ed7d899 330 SMART SM00470 68 158 3.1E-34 T 06-07-2017 IPR003115 ParB/Sulfiredoxin CAK77_RS21505 021dfb90ded4969de65d95b677daf27f 283 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 11 218 9.5E-12 T 06-07-2017 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 CAK77_RS08475 d3cfded82fe77d3236375a0e6df61e91 391 Pfam PF04055 Radical SAM superfamily 24 197 3.6E-19 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 CAK77_RS08475 d3cfded82fe77d3236375a0e6df61e91 391 SUPERFAMILY SSF102114 10 390 7.06E-109 T 06-07-2017 CAK77_RS08475 d3cfded82fe77d3236375a0e6df61e91 391 Gene3D G3DSA:3.80.30.20 22 258 3.4E-33 T 06-07-2017 IPR023404 Radical SAM, alpha/beta horseshoe CAK77_RS08475 d3cfded82fe77d3236375a0e6df61e91 391 SMART SM00729 19 244 8.1E-52 T 06-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CAK77_RS08475 d3cfded82fe77d3236375a0e6df61e91 391 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 22 348 3.8E-75 T 06-07-2017 IPR004559 Coproporphyrinogen III oxidase, oxygen-independent related GO:0004109|GO:0005737|GO:0006779|GO:0055114 CAK77_RS00825 980e4f8a1e6d59950703e151db265550 308 SUPERFAMILY SSF53850 3 192 3.7E-44 T 06-07-2017 CAK77_RS00825 980e4f8a1e6d59950703e151db265550 308 PIRSF PIRSF001500 1 281 1.2E-53 T 06-07-2017 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 CAK77_RS00825 980e4f8a1e6d59950703e151db265550 308 Gene3D G3DSA:3.40.190.10 3 97 1.7E-22 T 06-07-2017 CAK77_RS00825 980e4f8a1e6d59950703e151db265550 308 Pfam PF01842 ACT domain 201 264 2.9E-7 T 06-07-2017 IPR002912 ACT domain GO:0008152|GO:0016597 CAK77_RS00825 980e4f8a1e6d59950703e151db265550 308 Pfam PF00800 Prephenate dehydratase 4 187 1.1E-44 T 06-07-2017 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 CAK77_RS00825 980e4f8a1e6d59950703e151db265550 308 Gene3D G3DSA:3.30.70.260 194 279 2.0E-28 T 06-07-2017 CAK77_RS00825 980e4f8a1e6d59950703e151db265550 308 ProSitePatterns PS00858 Prephenate dehydratase signature 2. 227 234 - T 06-07-2017 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 CAK77_RS00825 980e4f8a1e6d59950703e151db265550 308 Gene3D G3DSA:3.40.190.10 98 175 6.2E-16 T 06-07-2017 CAK77_RS00825 980e4f8a1e6d59950703e151db265550 308 SUPERFAMILY SSF55021 182 279 9.16E-25 T 06-07-2017 CAK77_RS00930 af52a803bd8d252264c167cfb3f99f59 418 SUPERFAMILY SSF55681 132 417 6.36E-85 T 06-07-2017 CAK77_RS00930 af52a803bd8d252264c167cfb3f99f59 418 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 217 393 2.8E-25 T 06-07-2017 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK77_RS00930 af52a803bd8d252264c167cfb3f99f59 418 SUPERFAMILY SSF46589 2 111 1.1E-20 T 06-07-2017 IPR010978 tRNA-binding arm GO:0000166 CAK77_RS00930 af52a803bd8d252264c167cfb3f99f59 418 PIRSF PIRSF001529 1 418 2.5E-130 T 06-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CAK77_RS00930 af52a803bd8d252264c167cfb3f99f59 418 PRINTS PR00981 Seryl-tRNA synthetase signature 271 284 2.4E-30 T 06-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CAK77_RS00930 af52a803bd8d252264c167cfb3f99f59 418 PRINTS PR00981 Seryl-tRNA synthetase signature 328 344 2.4E-30 T 06-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CAK77_RS00930 af52a803bd8d252264c167cfb3f99f59 418 PRINTS PR00981 Seryl-tRNA synthetase signature 259 271 2.4E-30 T 06-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CAK77_RS00930 af52a803bd8d252264c167cfb3f99f59 418 PRINTS PR00981 Seryl-tRNA synthetase signature 311 324 2.4E-30 T 06-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CAK77_RS00930 af52a803bd8d252264c167cfb3f99f59 418 PRINTS PR00981 Seryl-tRNA synthetase signature 346 362 2.4E-30 T 06-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CAK77_RS00930 af52a803bd8d252264c167cfb3f99f59 418 Gene3D G3DSA:3.30.930.10 104 413 2.0E-114 T 06-07-2017 CAK77_RS00930 af52a803bd8d252264c167cfb3f99f59 418 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 415 37.717 T 06-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CAK77_RS00930 af52a803bd8d252264c167cfb3f99f59 418 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 106 8.4E-22 T 06-07-2017 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CAK77_RS00930 af52a803bd8d252264c167cfb3f99f59 418 TIGRFAM TIGR00414 serS: serine--tRNA ligase 2 409 1.7E-124 T 06-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CAK77_RS00930 af52a803bd8d252264c167cfb3f99f59 418 Gene3D G3DSA:1.10.287.40 2 102 1.8E-26 T 06-07-2017 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CAK77_RS24155 24b2b264cc2017d4ce8c88eb83a98231 432 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 12 132 6.4E-16 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS24155 24b2b264cc2017d4ce8c88eb83a98231 432 Gene3D G3DSA:2.40.110.10 135 233 1.1E-34 T 06-07-2017 CAK77_RS24155 24b2b264cc2017d4ce8c88eb83a98231 432 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 136 222 7.3E-22 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAK77_RS24155 24b2b264cc2017d4ce8c88eb83a98231 432 SUPERFAMILY SSF47203 242 399 1.26E-36 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS24155 24b2b264cc2017d4ce8c88eb83a98231 432 Gene3D G3DSA:1.10.540.10 7 133 3.3E-26 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS24155 24b2b264cc2017d4ce8c88eb83a98231 432 SUPERFAMILY SSF56645 4 256 6.68E-65 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK77_RS24155 24b2b264cc2017d4ce8c88eb83a98231 432 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 246 394 1.2E-27 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS24155 24b2b264cc2017d4ce8c88eb83a98231 432 Gene3D G3DSA:1.20.140.10 234 399 1.4E-38 T 06-07-2017 CAK77_RS22910 f41a69a08c4dc07643b2c67179b41e0a 321 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 139 160 - T 06-07-2017 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 CAK77_RS22910 f41a69a08c4dc07643b2c67179b41e0a 321 Gene3D G3DSA:3.90.180.10 1 144 2.8E-38 T 06-07-2017 IPR011032 GroES-like CAK77_RS22910 f41a69a08c4dc07643b2c67179b41e0a 321 SMART SM00829 10 319 1.9E-24 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAK77_RS22910 f41a69a08c4dc07643b2c67179b41e0a 321 Gene3D G3DSA:3.40.50.720 145 260 7.1E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS22910 f41a69a08c4dc07643b2c67179b41e0a 321 SUPERFAMILY SSF50129 1 139 9.43E-35 T 06-07-2017 IPR011032 GroES-like CAK77_RS22910 f41a69a08c4dc07643b2c67179b41e0a 321 Pfam PF00107 Zinc-binding dehydrogenase 150 269 7.6E-28 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAK77_RS22910 f41a69a08c4dc07643b2c67179b41e0a 321 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 88 1.5E-9 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAK77_RS22910 f41a69a08c4dc07643b2c67179b41e0a 321 SUPERFAMILY SSF51735 111 269 1.58E-41 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS11725 e2fff029c875136baa021d6b4a841cb6 135 Pfam PF03965 Penicillinase repressor 7 120 9.7E-29 T 06-07-2017 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 CAK77_RS11725 e2fff029c875136baa021d6b4a841cb6 135 Gene3D G3DSA:1.10.10.10 4 81 2.2E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS11725 e2fff029c875136baa021d6b4a841cb6 135 PIRSF PIRSF019455 3 130 6.2E-22 T 06-07-2017 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 CAK77_RS11725 e2fff029c875136baa021d6b4a841cb6 135 SUPERFAMILY SSF46785 4 122 2.21E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS17465 8c4d9737da43347f31682b052b406bd5 403 Gene3D G3DSA:1.20.140.10 244 397 7.6E-45 T 06-07-2017 CAK77_RS17465 8c4d9737da43347f31682b052b406bd5 403 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 132 226 7.6E-25 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAK77_RS17465 8c4d9737da43347f31682b052b406bd5 403 SUPERFAMILY SSF56645 4 236 2.36E-41 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK77_RS17465 8c4d9737da43347f31682b052b406bd5 403 Gene3D G3DSA:2.40.110.10 132 238 1.4E-34 T 06-07-2017 CAK77_RS17465 8c4d9737da43347f31682b052b406bd5 403 SUPERFAMILY SSF47203 243 397 2.74E-31 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS17465 8c4d9737da43347f31682b052b406bd5 403 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 244 395 1.7E-33 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS20930 040f29eba75433fad403090a15273cd7 432 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 185 210 3.2E-5 T 06-07-2017 CAK77_RS20930 040f29eba75433fad403090a15273cd7 432 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 143 152 3.2E-5 T 06-07-2017 CAK77_RS20930 040f29eba75433fad403090a15273cd7 432 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 3.2E-5 T 06-07-2017 CAK77_RS20930 040f29eba75433fad403090a15273cd7 432 Gene3D G3DSA:3.50.50.60 3 216 5.8E-16 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS20930 040f29eba75433fad403090a15273cd7 432 SUPERFAMILY SSF51905 2 221 1.73E-22 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS20930 040f29eba75433fad403090a15273cd7 432 Pfam PF13454 FAD-NAD(P)-binding 5 149 6.9E-36 T 06-07-2017 CAK77_RS20930 040f29eba75433fad403090a15273cd7 432 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 185 203 4.5E-8 T 06-07-2017 CAK77_RS20930 040f29eba75433fad403090a15273cd7 432 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 4.5E-8 T 06-07-2017 CAK77_RS20930 040f29eba75433fad403090a15273cd7 432 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 140 158 4.5E-8 T 06-07-2017 CAK77_RS24280 577f265fc89bebd24f704cd6a19d17fc 271 Gene3D G3DSA:3.90.79.10 112 229 6.1E-30 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAK77_RS24280 577f265fc89bebd24f704cd6a19d17fc 271 Pfam PF00293 NUDIX domain 109 217 3.2E-21 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 CAK77_RS24280 577f265fc89bebd24f704cd6a19d17fc 271 ProSitePatterns PS00893 Nudix box signature. 130 151 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CAK77_RS24280 577f265fc89bebd24f704cd6a19d17fc 271 SUPERFAMILY SSF55811 94 222 1.35E-31 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAK77_RS24280 577f265fc89bebd24f704cd6a19d17fc 271 PRINTS PR00502 NUDIX hydrolase family signature 139 154 9.2E-8 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CAK77_RS24280 577f265fc89bebd24f704cd6a19d17fc 271 PRINTS PR00502 NUDIX hydrolase family signature 125 139 9.2E-8 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CAK77_RS22740 b2b0dc3bd3895e41f715168ed17b4032 530 Pfam PF13193 AMP-binding enzyme C-terminal domain 442 516 2.9E-18 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAK77_RS22740 b2b0dc3bd3895e41f715168ed17b4032 530 ProSitePatterns PS00455 Putative AMP-binding domain signature. 185 196 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK77_RS22740 b2b0dc3bd3895e41f715168ed17b4032 530 Gene3D G3DSA:3.40.50.980 191 351 1.2E-29 T 06-07-2017 CAK77_RS22740 b2b0dc3bd3895e41f715168ed17b4032 530 Pfam PF00501 AMP-binding enzyme 30 433 3.3E-103 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK77_RS22740 b2b0dc3bd3895e41f715168ed17b4032 530 Gene3D G3DSA:2.30.38.10 352 424 3.5E-30 T 06-07-2017 CAK77_RS22740 b2b0dc3bd3895e41f715168ed17b4032 530 Gene3D G3DSA:3.40.50.980 26 190 1.2E-39 T 06-07-2017 CAK77_RS22740 b2b0dc3bd3895e41f715168ed17b4032 530 Gene3D G3DSA:3.30.300.30 428 525 1.1E-30 T 06-07-2017 CAK77_RS22740 b2b0dc3bd3895e41f715168ed17b4032 530 SUPERFAMILY SSF56801 19 526 1.22E-150 T 06-07-2017 CAK77_RS16715 7338cd3d02737a1302dfc138f6cf3719 954 Gene3D G3DSA:1.10.10.10 895 950 3.3E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS16715 7338cd3d02737a1302dfc138f6cf3719 954 Pfam PF00196 Bacterial regulatory proteins, luxR family 899 950 9.7E-14 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK77_RS16715 7338cd3d02737a1302dfc138f6cf3719 954 SUPERFAMILY SSF46894 894 950 5.78E-15 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAK77_RS16715 7338cd3d02737a1302dfc138f6cf3719 954 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 930 942 1.8E-8 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK77_RS16715 7338cd3d02737a1302dfc138f6cf3719 954 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 900 914 1.8E-8 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK77_RS16715 7338cd3d02737a1302dfc138f6cf3719 954 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 914 930 1.8E-8 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK77_RS16715 7338cd3d02737a1302dfc138f6cf3719 954 SMART SM00421 897 954 2.8E-15 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK77_RS16715 7338cd3d02737a1302dfc138f6cf3719 954 Gene3D G3DSA:3.40.50.300 49 188 2.4E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS16715 7338cd3d02737a1302dfc138f6cf3719 954 SUPERFAMILY SSF52540 30 258 2.23E-10 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS16715 7338cd3d02737a1302dfc138f6cf3719 954 Pfam PF13191 AAA ATPase domain 39 196 2.7E-16 T 06-07-2017 CAK77_RS16715 7338cd3d02737a1302dfc138f6cf3719 954 Gene3D G3DSA:1.25.40.10 401 471 2.5E-9 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK77_RS16715 7338cd3d02737a1302dfc138f6cf3719 954 Gene3D G3DSA:1.25.40.10 646 862 2.5E-9 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK77_RS19060 14064633a2d7512eae2d295ee4ae4d56 213 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 16 200 9.3E-68 T 06-07-2017 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS19060 14064633a2d7512eae2d295ee4ae4d56 213 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 8 207 31.98 T 06-07-2017 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS19060 14064633a2d7512eae2d295ee4ae4d56 213 SUPERFAMILY SSF52166 2 203 7.19E-70 T 06-07-2017 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 CAK77_RS19060 14064633a2d7512eae2d295ee4ae4d56 213 Gene3D G3DSA:3.40.1370.10 57 202 5.4E-50 T 06-07-2017 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 CAK77_RS19060 14064633a2d7512eae2d295ee4ae4d56 213 Pfam PF00573 Ribosomal protein L4/L1 family 16 201 2.4E-62 T 06-07-2017 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 CAK77_RS09760 02dd16d88ccabec2019607bd11400926 490 Pfam PF01225 Mur ligase family, catalytic domain 13 116 5.7E-23 T 06-07-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CAK77_RS09760 02dd16d88ccabec2019607bd11400926 490 Gene3D G3DSA:3.40.50.720 11 102 4.9E-28 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS09760 02dd16d88ccabec2019607bd11400926 490 SUPERFAMILY SSF53244 329 475 3.66E-41 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CAK77_RS09760 02dd16d88ccabec2019607bd11400926 490 Gene3D G3DSA:3.90.190.20 332 477 9.0E-48 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CAK77_RS09760 02dd16d88ccabec2019607bd11400926 490 Pfam PF02875 Mur ligase family, glutamate ligase domain 330 416 2.8E-21 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CAK77_RS09760 02dd16d88ccabec2019607bd11400926 490 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 10 478 38.053 T 06-07-2017 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK77_RS09760 02dd16d88ccabec2019607bd11400926 490 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 13 472 4.9E-148 T 06-07-2017 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK77_RS09760 02dd16d88ccabec2019607bd11400926 490 Pfam PF08245 Mur ligase middle domain 120 310 2.8E-26 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAK77_RS09760 02dd16d88ccabec2019607bd11400926 490 Gene3D G3DSA:3.40.1190.10 104 331 5.9E-77 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAK77_RS09760 02dd16d88ccabec2019607bd11400926 490 SUPERFAMILY SSF51984 11 101 1.11E-19 T 06-07-2017 CAK77_RS09760 02dd16d88ccabec2019607bd11400926 490 SUPERFAMILY SSF53623 104 328 8.7E-55 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAK77_RS03795 d4836653759b61f17f1d5f466aee535f 262 Pfam PF13344 Haloacid dehalogenase-like hydrolase 7 97 4.8E-16 T 06-07-2017 IPR006357 HAD-superfamily hydrolase, subfamily IIA CAK77_RS03795 d4836653759b61f17f1d5f466aee535f 262 Gene3D G3DSA:3.40.50.1000 177 255 1.1E-32 T 06-07-2017 IPR023214 HAD-like domain CAK77_RS03795 d4836653759b61f17f1d5f466aee535f 262 Gene3D G3DSA:3.40.50.1000 6 77 1.1E-32 T 06-07-2017 IPR023214 HAD-like domain CAK77_RS03795 d4836653759b61f17f1d5f466aee535f 262 SUPERFAMILY SSF56784 6 251 1.43E-43 T 06-07-2017 IPR023214 HAD-like domain CAK77_RS03795 d4836653759b61f17f1d5f466aee535f 262 Gene3D G3DSA:3.40.50.10410 78 176 3.1E-20 T 06-07-2017 IPR023215 Nitrophenylphosphatase-like domain CAK77_RS03795 d4836653759b61f17f1d5f466aee535f 262 Pfam PF13242 HAD-hyrolase-like 178 250 3.2E-15 T 06-07-2017 CAK77_RS08435 a4533fd6557e6fbce8cd4b1cd858bdce 270 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 73 263 5.6E-19 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS08435 a4533fd6557e6fbce8cd4b1cd858bdce 270 TIGRFAM TIGR00969 3a0106s02: sulfate ABC transporter, permease protein 7 262 1.0E-103 T 06-07-2017 IPR005667 Sulphate ABC transporter permease protein 2 GO:0008272|GO:0015419|GO:0016020 CAK77_RS08435 a4533fd6557e6fbce8cd4b1cd858bdce 270 TIGRFAM TIGR02140 permease_CysW: sulfate ABC transporter, permease protein CysW 7 265 6.9E-108 T 06-07-2017 IPR011866 Sulphate ABC transporter, permease protein CysW GO:0008272|GO:0015116|GO:0016021 CAK77_RS08435 a4533fd6557e6fbce8cd4b1cd858bdce 270 SUPERFAMILY SSF161098 16 257 1.44E-53 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS08435 a4533fd6557e6fbce8cd4b1cd858bdce 270 Gene3D G3DSA:1.10.3720.10 11 265 5.9E-52 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS08785 f8350e4932cb5fbb46bc218303587c99 338 SMART SM00387 226 332 6.1E-34 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS08785 f8350e4932cb5fbb46bc218303587c99 338 SMART SM00304 65 117 2.9E-16 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAK77_RS08785 f8350e4932cb5fbb46bc218303587c99 338 SUPERFAMILY SSF55874 171 331 2.62E-40 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS08785 f8350e4932cb5fbb46bc218303587c99 338 Pfam PF00672 HAMP domain 48 113 1.3E-19 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAK77_RS08785 f8350e4932cb5fbb46bc218303587c99 338 Pfam PF00512 His Kinase A (phospho-acceptor) domain 119 182 2.4E-16 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK77_RS08785 f8350e4932cb5fbb46bc218303587c99 338 Gene3D G3DSA:3.30.565.10 168 330 9.2E-40 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS08785 f8350e4932cb5fbb46bc218303587c99 338 SUPERFAMILY SSF158472 67 114 5.36E-12 T 06-07-2017 CAK77_RS08785 f8350e4932cb5fbb46bc218303587c99 338 PRINTS PR00344 Bacterial sensor protein C-terminal signature 294 312 2.2E-11 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK77_RS08785 f8350e4932cb5fbb46bc218303587c99 338 PRINTS PR00344 Bacterial sensor protein C-terminal signature 263 277 2.2E-11 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK77_RS08785 f8350e4932cb5fbb46bc218303587c99 338 PRINTS PR00344 Bacterial sensor protein C-terminal signature 281 291 2.2E-11 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK77_RS08785 f8350e4932cb5fbb46bc218303587c99 338 Gene3D G3DSA:1.10.287.130 108 167 7.7E-18 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK77_RS08785 f8350e4932cb5fbb46bc218303587c99 338 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 227 330 2.2E-22 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS08785 f8350e4932cb5fbb46bc218303587c99 338 SMART SM00388 118 182 4.9E-19 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK77_RS08785 f8350e4932cb5fbb46bc218303587c99 338 SUPERFAMILY SSF47384 101 183 1.86E-20 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK77_RS19710 71174b8b26b07db20ef47a90c54c1294 322 SMART SM00922 89 182 1.8E-13 T 06-07-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CAK77_RS19710 71174b8b26b07db20ef47a90c54c1294 322 Pfam PF13378 Enolase C-terminal domain-like 101 286 1.7E-27 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAK77_RS19710 71174b8b26b07db20ef47a90c54c1294 322 Gene3D G3DSA:3.30.390.10 10 97 4.0E-44 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAK77_RS19710 71174b8b26b07db20ef47a90c54c1294 322 Hamap MF_00470 o-succinylbenzoate synthase [menC]. 7 288 22.581 T 06-07-2017 IPR010196 o-succinylbenzoate synthase, MenC type1 GO:0000287|GO:0009234|GO:0016836 KEGG: 00010+4.2.1.11|KEGG: 00130+4.2.1.113|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-5837|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAK77_RS19710 71174b8b26b07db20ef47a90c54c1294 322 Gene3D G3DSA:3.20.20.120 98 261 3.0E-43 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAK77_RS19710 71174b8b26b07db20ef47a90c54c1294 322 SUPERFAMILY SSF51604 75 286 2.23E-43 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAK77_RS21865 71e12c3ba95e51c744cbad59bf8938aa 275 PIRSF PIRSF015582 1 273 2.0E-62 T 06-07-2017 IPR011206 Citrate lyase beta subunit-like CAK77_RS21865 71e12c3ba95e51c744cbad59bf8938aa 275 Gene3D G3DSA:3.20.20.60 9 223 1.1E-59 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAK77_RS21865 71e12c3ba95e51c744cbad59bf8938aa 275 SUPERFAMILY SSF51621 9 223 2.79E-55 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAK77_RS21865 71e12c3ba95e51c744cbad59bf8938aa 275 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 11 211 2.2E-23 T 06-07-2017 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 CAK77_RS21235 21a1c2b0cec88491af020433960f7d65 253 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK77_RS21235 21a1c2b0cec88491af020433960f7d65 253 PIRSF PIRSF039085 1 253 1.7E-108 T 06-07-2017 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CAK77_RS21235 21a1c2b0cec88491af020433960f7d65 253 Pfam PF00005 ABC transporter 19 177 7.9E-36 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK77_RS21235 21a1c2b0cec88491af020433960f7d65 253 SMART SM00382 28 225 2.2E-19 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS21235 21a1c2b0cec88491af020433960f7d65 253 SUPERFAMILY SSF52540 4 247 6.15E-77 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS21235 21a1c2b0cec88491af020433960f7d65 253 Gene3D G3DSA:3.40.50.300 3 249 5.3E-85 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS02750 0567a0d0ba4d404ec8a64188020fe89e 321 PRINTS PR00412 Epoxide hydrolase signature 37 55 2.2E-33 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK77_RS02750 0567a0d0ba4d404ec8a64188020fe89e 321 PRINTS PR00412 Epoxide hydrolase signature 57 72 2.2E-33 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK77_RS02750 0567a0d0ba4d404ec8a64188020fe89e 321 PRINTS PR00412 Epoxide hydrolase signature 117 130 2.2E-33 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK77_RS02750 0567a0d0ba4d404ec8a64188020fe89e 321 PRINTS PR00412 Epoxide hydrolase signature 293 315 2.2E-33 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK77_RS02750 0567a0d0ba4d404ec8a64188020fe89e 321 PRINTS PR00412 Epoxide hydrolase signature 103 116 2.2E-33 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK77_RS02750 0567a0d0ba4d404ec8a64188020fe89e 321 PRINTS PR00412 Epoxide hydrolase signature 259 275 2.2E-33 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK77_RS02750 0567a0d0ba4d404ec8a64188020fe89e 321 Gene3D G3DSA:3.40.50.1820 7 319 9.3E-85 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS02750 0567a0d0ba4d404ec8a64188020fe89e 321 SUPERFAMILY SSF53474 8 318 8.11E-71 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS02750 0567a0d0ba4d404ec8a64188020fe89e 321 Pfam PF00561 alpha/beta hydrolase fold 31 304 1.6E-25 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS02750 0567a0d0ba4d404ec8a64188020fe89e 321 PRINTS PR00111 Alpha/beta hydrolase fold signature 103 116 1.6E-5 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS02750 0567a0d0ba4d404ec8a64188020fe89e 321 PRINTS PR00111 Alpha/beta hydrolase fold signature 57 72 1.6E-5 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS02750 0567a0d0ba4d404ec8a64188020fe89e 321 PRINTS PR00111 Alpha/beta hydrolase fold signature 117 130 1.6E-5 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS16575 28cf1e7a306db1205a8437bc054a9fc4 499 Pfam PF02934 GatB/GatE catalytic domain 17 311 2.3E-104 T 06-07-2017 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 CAK77_RS16575 28cf1e7a306db1205a8437bc054a9fc4 499 SUPERFAMILY SSF89095 349 494 1.57E-22 T 06-07-2017 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 CAK77_RS16575 28cf1e7a306db1205a8437bc054a9fc4 499 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 13 497 35.483 T 06-07-2017 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 CAK77_RS16575 28cf1e7a306db1205a8437bc054a9fc4 499 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 13 494 5.2E-144 T 06-07-2017 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 CAK77_RS16575 28cf1e7a306db1205a8437bc054a9fc4 499 SMART SM00845 349 496 9.1E-53 T 06-07-2017 IPR018027 Asn/Gln amidotransferase GO:0016884 CAK77_RS16575 28cf1e7a306db1205a8437bc054a9fc4 499 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 162 176 - T 06-07-2017 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 CAK77_RS16575 28cf1e7a306db1205a8437bc054a9fc4 499 Gene3D G3DSA:1.10.10.410 440 493 1.3E-4 T 06-07-2017 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal CAK77_RS16575 28cf1e7a306db1205a8437bc054a9fc4 499 SUPERFAMILY SSF55931 15 318 2.88E-110 T 06-07-2017 CAK77_RS16575 28cf1e7a306db1205a8437bc054a9fc4 499 Pfam PF02637 GatB domain 350 494 1.1E-38 T 06-07-2017 IPR018027 Asn/Gln amidotransferase GO:0016884 CAK77_RS10940 281514dec0b1e66a6e14172339e7c590 912 Pfam PF13646 HEAT repeats 642 697 4.2E-8 T 06-07-2017 CAK77_RS10940 281514dec0b1e66a6e14172339e7c590 912 Pfam PF13646 HEAT repeats 824 910 4.2E-10 T 06-07-2017 CAK77_RS10940 281514dec0b1e66a6e14172339e7c590 912 SUPERFAMILY SSF51905 11 287 4.13E-54 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS10940 281514dec0b1e66a6e14172339e7c590 912 SUPERFAMILY SSF51905 383 454 4.13E-54 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS10940 281514dec0b1e66a6e14172339e7c590 912 SUPERFAMILY SSF46977 453 579 3.79E-34 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK77_RS10940 281514dec0b1e66a6e14172339e7c590 912 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 15 37 1.2E-7 T 06-07-2017 CAK77_RS10940 281514dec0b1e66a6e14172339e7c590 912 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 411 426 1.2E-7 T 06-07-2017 CAK77_RS10940 281514dec0b1e66a6e14172339e7c590 912 Pfam PF00890 FAD binding domain 15 406 3.3E-35 T 06-07-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK77_RS10940 281514dec0b1e66a6e14172339e7c590 912 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 16 35 4.3E-12 T 06-07-2017 CAK77_RS10940 281514dec0b1e66a6e14172339e7c590 912 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 382 404 4.3E-12 T 06-07-2017 CAK77_RS10940 281514dec0b1e66a6e14172339e7c590 912 SMART SM00567 E-Z type HEAT repeats 866 897 78.0 T 06-07-2017 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CAK77_RS10940 281514dec0b1e66a6e14172339e7c590 912 SMART SM00567 E-Z type HEAT repeats 835 864 33.0 T 06-07-2017 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CAK77_RS10940 281514dec0b1e66a6e14172339e7c590 912 SMART SM00567 E-Z type HEAT repeats 803 833 0.43 T 06-07-2017 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CAK77_RS10940 281514dec0b1e66a6e14172339e7c590 912 SMART SM00567 E-Z type HEAT repeats 653 682 240.0 T 06-07-2017 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CAK77_RS10940 281514dec0b1e66a6e14172339e7c590 912 Pfam PF02910 Fumarate reductase flavoprotein C-term 468 576 1.9E-13 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK77_RS10940 281514dec0b1e66a6e14172339e7c590 912 Gene3D G3DSA:1.25.10.10 621 750 3.5E-15 T 06-07-2017 IPR011989 Armadillo-like helical CAK77_RS10940 281514dec0b1e66a6e14172339e7c590 912 Gene3D G3DSA:1.25.10.10 751 910 5.4E-26 T 06-07-2017 IPR011989 Armadillo-like helical CAK77_RS10940 281514dec0b1e66a6e14172339e7c590 912 Gene3D G3DSA:3.50.50.60 383 442 4.0E-68 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS10940 281514dec0b1e66a6e14172339e7c590 912 Gene3D G3DSA:3.50.50.60 12 304 4.0E-68 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS10940 281514dec0b1e66a6e14172339e7c590 912 SUPERFAMILY SSF48371 636 884 1.82E-32 T 06-07-2017 IPR016024 Armadillo-type fold GO:0005488 CAK77_RS10940 281514dec0b1e66a6e14172339e7c590 912 Gene3D G3DSA:1.20.58.100 443 551 6.3E-33 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK77_RS11840 70824031c258e09ddf8210d2fa761ac1 1282 Gene3D G3DSA:1.20.990.10 962 1066 1.5E-21 T 06-07-2017 IPR023173 NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain-3 GO:0016491|GO:0055114 CAK77_RS11840 70824031c258e09ddf8210d2fa761ac1 1282 SUPERFAMILY SSF52343 1127 1282 1.83E-48 T 06-07-2017 CAK77_RS11840 70824031c258e09ddf8210d2fa761ac1 1282 Pfam PF00384 Molybdopterin oxidoreductase 96 498 3.3E-72 T 06-07-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS11840 70824031c258e09ddf8210d2fa761ac1 1282 Gene3D G3DSA:3.40.50.80 1138 1281 4.3E-55 T 06-07-2017 CAK77_RS11840 70824031c258e09ddf8210d2fa761ac1 1282 Gene3D G3DSA:3.40.228.10 148 331 4.7E-66 T 06-07-2017 CAK77_RS11840 70824031c258e09ddf8210d2fa761ac1 1282 SUPERFAMILY SSF63380 911 1129 1.52E-56 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CAK77_RS11840 70824031c258e09ddf8210d2fa761ac1 1282 SUPERFAMILY SSF50692 581 725 3.11E-45 T 06-07-2017 IPR009010 Aspartate decarboxylase-like domain CAK77_RS11840 70824031c258e09ddf8210d2fa761ac1 1282 Pfam PF00667 FAD binding domain 912 1108 1.7E-25 T 06-07-2017 IPR003097 FAD-binding, type 1 GO:0016491|GO:0055114 CAK77_RS11840 70824031c258e09ddf8210d2fa761ac1 1282 Pfam PF00175 Oxidoreductase NAD-binding domain 1140 1246 1.9E-17 T 06-07-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CAK77_RS11840 70824031c258e09ddf8210d2fa761ac1 1282 Gene3D G3DSA:2.40.30.10 911 961 2.1E-34 T 06-07-2017 CAK77_RS11840 70824031c258e09ddf8210d2fa761ac1 1282 Gene3D G3DSA:2.40.30.10 1067 1137 2.1E-34 T 06-07-2017 CAK77_RS11840 70824031c258e09ddf8210d2fa761ac1 1282 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 12 65 1.9E-13 T 06-07-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS11840 70824031c258e09ddf8210d2fa761ac1 1282 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 1231 1239 8.2E-26 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK77_RS11840 70824031c258e09ddf8210d2fa761ac1 1282 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 1103 1112 8.2E-26 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK77_RS11840 70824031c258e09ddf8210d2fa761ac1 1282 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 1177 1188 8.2E-26 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK77_RS11840 70824031c258e09ddf8210d2fa761ac1 1282 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 951 961 8.2E-26 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK77_RS11840 70824031c258e09ddf8210d2fa761ac1 1282 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 1139 1158 8.2E-26 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK77_RS11840 70824031c258e09ddf8210d2fa761ac1 1282 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 1164 1173 8.2E-26 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK77_RS11840 70824031c258e09ddf8210d2fa761ac1 1282 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 1069 1076 8.2E-26 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK77_RS11840 70824031c258e09ddf8210d2fa761ac1 1282 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 1208 1224 8.2E-26 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK77_RS11840 70824031c258e09ddf8210d2fa761ac1 1282 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 13 31 - T 06-07-2017 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 KEGG: 00910+1.7.99.4 CAK77_RS11840 70824031c258e09ddf8210d2fa761ac1 1282 Pfam PF00258 Flavodoxin 747 869 4.7E-25 T 06-07-2017 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 CAK77_RS11840 70824031c258e09ddf8210d2fa761ac1 1282 PRINTS PR00369 Flavodoxin signature 825 835 3.5E-9 T 06-07-2017 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 CAK77_RS11840 70824031c258e09ddf8210d2fa761ac1 1282 PRINTS PR00369 Flavodoxin signature 794 805 3.5E-9 T 06-07-2017 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 CAK77_RS11840 70824031c258e09ddf8210d2fa761ac1 1282 PRINTS PR00369 Flavodoxin signature 746 759 3.5E-9 T 06-07-2017 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 CAK77_RS11840 70824031c258e09ddf8210d2fa761ac1 1282 PRINTS PR00369 Flavodoxin signature 849 868 3.5E-9 T 06-07-2017 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 CAK77_RS11840 70824031c258e09ddf8210d2fa761ac1 1282 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 648 675 - T 06-07-2017 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 CAK77_RS11840 70824031c258e09ddf8210d2fa761ac1 1282 SMART SM00926 8 66 7.4E-11 T 06-07-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS11840 70824031c258e09ddf8210d2fa761ac1 1282 SUPERFAMILY SSF52218 744 886 1.39E-39 T 06-07-2017 IPR029039 Flavoprotein-like domain CAK77_RS11840 70824031c258e09ddf8210d2fa761ac1 1282 Gene3D G3DSA:3.40.50.740 332 543 5.4E-74 T 06-07-2017 CAK77_RS11840 70824031c258e09ddf8210d2fa761ac1 1282 Gene3D G3DSA:3.40.50.740 91 147 5.4E-74 T 06-07-2017 CAK77_RS11840 70824031c258e09ddf8210d2fa761ac1 1282 Gene3D G3DSA:2.20.25.90 12 65 1.7E-14 T 06-07-2017 CAK77_RS11840 70824031c258e09ddf8210d2fa761ac1 1282 Gene3D G3DSA:2.40.40.20 544 725 5.4E-56 T 06-07-2017 CAK77_RS11840 70824031c258e09ddf8210d2fa761ac1 1282 Pfam PF01568 Molydopterin dinucleotide binding domain 610 718 5.3E-33 T 06-07-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CAK77_RS11840 70824031c258e09ddf8210d2fa761ac1 1282 SUPERFAMILY SSF53706 11 621 1.31E-178 T 06-07-2017 CAK77_RS11840 70824031c258e09ddf8210d2fa761ac1 1282 Gene3D G3DSA:3.40.50.360 736 886 3.3E-38 T 06-07-2017 IPR029039 Flavoprotein-like domain CAK77_RS20040 8e8cefed740b3b50024abda06ed7132d 309 SUPERFAMILY SSF51412 3 302 6.11E-62 T 06-07-2017 CAK77_RS20040 8e8cefed740b3b50024abda06ed7132d 309 Gene3D G3DSA:3.20.20.70 2 245 7.2E-59 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK77_RS20040 8e8cefed740b3b50024abda06ed7132d 309 Gene3D G3DSA:3.20.20.70 278 293 7.2E-59 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK77_RS20040 8e8cefed740b3b50024abda06ed7132d 309 Pfam PF03060 Nitronate monooxygenase 5 253 8.4E-53 T 06-07-2017 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 CAK77_RS00620 f9c1439602956b8196997c062f6e66ef 488 PRINTS PR00419 Adrenodoxin reductase family signature 211 221 3.0E-24 T 06-07-2017 CAK77_RS00620 f9c1439602956b8196997c062f6e66ef 488 PRINTS PR00419 Adrenodoxin reductase family signature 146 168 3.0E-24 T 06-07-2017 CAK77_RS00620 f9c1439602956b8196997c062f6e66ef 488 PRINTS PR00419 Adrenodoxin reductase family signature 290 304 3.0E-24 T 06-07-2017 CAK77_RS00620 f9c1439602956b8196997c062f6e66ef 488 PRINTS PR00419 Adrenodoxin reductase family signature 169 182 3.0E-24 T 06-07-2017 CAK77_RS00620 f9c1439602956b8196997c062f6e66ef 488 Gene3D G3DSA:3.40.50.720 146 368 4.4E-60 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS00620 f9c1439602956b8196997c062f6e66ef 488 SUPERFAMILY SSF51971 376 471 5.65E-11 T 06-07-2017 CAK77_RS00620 f9c1439602956b8196997c062f6e66ef 488 TIGRFAM TIGR01317 GOGAT_sm_gam: glutamate synthase, NADH/NADPH, small subunit 3 477 1.8E-225 T 06-07-2017 IPR006005 Glutamate synthase, NADH/NADPH, small subunit 1 GO:0006537|GO:0016639|GO:0055114 CAK77_RS00620 f9c1439602956b8196997c062f6e66ef 488 SUPERFAMILY SSF46548 10 155 1.65E-38 T 06-07-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 CAK77_RS00620 f9c1439602956b8196997c062f6e66ef 488 Gene3D G3DSA:3.50.50.60 369 474 1.3E-21 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS00620 f9c1439602956b8196997c062f6e66ef 488 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 145 459 3.5E-26 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS00620 f9c1439602956b8196997c062f6e66ef 488 SUPERFAMILY SSF51971 143 404 1.29E-66 T 06-07-2017 CAK77_RS00620 f9c1439602956b8196997c062f6e66ef 488 Gene3D G3DSA:1.10.1060.10 10 145 2.1E-39 T 06-07-2017 CAK77_RS00620 f9c1439602956b8196997c062f6e66ef 488 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 27 132 1.7E-23 T 06-07-2017 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 CAK77_RS18810 ccc83718910531e40dae13e03e751f9d 201 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 201 34.082 T 06-07-2017 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 CAK77_RS18810 ccc83718910531e40dae13e03e751f9d 201 Gene3D G3DSA:3.10.290.10 97 185 4.7E-26 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 CAK77_RS18810 ccc83718910531e40dae13e03e751f9d 201 Gene3D G3DSA:1.10.1050.10 1 96 1.7E-38 T 06-07-2017 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 CAK77_RS18810 ccc83718910531e40dae13e03e751f9d 201 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 201 1.9E-80 T 06-07-2017 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 CAK77_RS18810 ccc83718910531e40dae13e03e751f9d 201 SMART SM00363 91 153 4.2E-17 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 CAK77_RS18810 ccc83718910531e40dae13e03e751f9d 201 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 90 4.2E-28 T 06-07-2017 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 CAK77_RS18810 ccc83718910531e40dae13e03e751f9d 201 SMART SM01390 3 90 6.7E-44 T 06-07-2017 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 CAK77_RS18810 ccc83718910531e40dae13e03e751f9d 201 SUPERFAMILY SSF55174 3 201 6.02E-63 T 06-07-2017 CAK77_RS18810 ccc83718910531e40dae13e03e751f9d 201 Pfam PF01479 S4 domain 92 137 1.7E-17 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 CAK77_RS18810 ccc83718910531e40dae13e03e751f9d 201 ProSitePatterns PS00632 Ribosomal protein S4 signature. 89 113 - T 06-07-2017 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK77_RS06475 55b1e13cbe4dc20dda883a4cec2cabdb 272 Gene3D G3DSA:3.40.50.150 11 188 2.5E-21 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS06475 55b1e13cbe4dc20dda883a4cec2cabdb 272 PIRSF PIRSF028177 5 271 1.6E-61 T 06-07-2017 IPR016874 Tetracenomycin polyketide synthesis O-methyltransferase TcmP GO:0017000|GO:1901106 CAK77_RS06475 55b1e13cbe4dc20dda883a4cec2cabdb 272 Pfam PF04072 Leucine carboxyl methyltransferase 19 173 2.2E-8 T 06-07-2017 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 CAK77_RS06475 55b1e13cbe4dc20dda883a4cec2cabdb 272 SUPERFAMILY SSF53335 15 253 2.84E-48 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS00850 7e34473159cc492f4be0baa9845a6274 296 SUPERFAMILY SSF53474 4 279 6.29E-49 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS00850 7e34473159cc492f4be0baa9845a6274 296 PRINTS PR00412 Epoxide hydrolase signature 255 277 1.9E-5 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK77_RS00850 7e34473159cc492f4be0baa9845a6274 296 PRINTS PR00412 Epoxide hydrolase signature 47 62 1.9E-5 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK77_RS00850 7e34473159cc492f4be0baa9845a6274 296 PRINTS PR00111 Alpha/beta hydrolase fold signature 91 104 4.9E-8 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS00850 7e34473159cc492f4be0baa9845a6274 296 PRINTS PR00111 Alpha/beta hydrolase fold signature 105 118 4.9E-8 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS00850 7e34473159cc492f4be0baa9845a6274 296 PRINTS PR00111 Alpha/beta hydrolase fold signature 47 62 4.9E-8 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS00850 7e34473159cc492f4be0baa9845a6274 296 Pfam PF12697 Alpha/beta hydrolase family 24 272 2.9E-18 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS00850 7e34473159cc492f4be0baa9845a6274 296 Gene3D G3DSA:3.40.50.1820 1 284 3.0E-57 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS02235 d3675c9e019e3463a259f00901eea2a4 67 Pfam PF12728 Helix-turn-helix domain 4 55 7.3E-15 T 06-07-2017 CAK77_RS02235 d3675c9e019e3463a259f00901eea2a4 67 SUPERFAMILY SSF46955 4 55 1.5E-9 T 06-07-2017 IPR009061 Putative DNA-binding domain CAK77_RS02235 d3675c9e019e3463a259f00901eea2a4 67 Gene3D G3DSA:1.10.10.10 4 59 5.1E-9 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS18615 01a24d0fe9ed62fe9bd936c2c9c718ef 99 SUPERFAMILY SSF50129 2 98 2.17E-35 T 06-07-2017 IPR011032 GroES-like CAK77_RS18615 01a24d0fe9ed62fe9bd936c2c9c718ef 99 SMART SM00883 4 97 5.4E-55 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CAK77_RS18615 01a24d0fe9ed62fe9bd936c2c9c718ef 99 Pfam PF00166 Chaperonin 10 Kd subunit 4 97 1.0E-34 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CAK77_RS18615 01a24d0fe9ed62fe9bd936c2c9c718ef 99 Hamap MF_00580 10 kDa chaperonin [groS]. 4 98 25.552 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CAK77_RS18615 01a24d0fe9ed62fe9bd936c2c9c718ef 99 Gene3D G3DSA:2.30.33.40 4 97 3.0E-37 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CAK77_RS18615 01a24d0fe9ed62fe9bd936c2c9c718ef 99 ProSitePatterns PS00681 Chaperonins cpn10 signature. 5 29 - T 06-07-2017 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 CAK77_RS18615 01a24d0fe9ed62fe9bd936c2c9c718ef 99 PRINTS PR00297 10kDa chaperonin signature 27 48 2.0E-30 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CAK77_RS18615 01a24d0fe9ed62fe9bd936c2c9c718ef 99 PRINTS PR00297 10kDa chaperonin signature 5 20 2.0E-30 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CAK77_RS18615 01a24d0fe9ed62fe9bd936c2c9c718ef 99 PRINTS PR00297 10kDa chaperonin signature 84 97 2.0E-30 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CAK77_RS18615 01a24d0fe9ed62fe9bd936c2c9c718ef 99 PRINTS PR00297 10kDa chaperonin signature 63 75 2.0E-30 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CAK77_RS18185 4771e2f5e2a863e5ad2c7c6658666c61 1517 Pfam PF00271 Helicase conserved C-terminal domain 354 417 2.4E-12 T 06-07-2017 IPR001650 Helicase, C-terminal CAK77_RS18185 4771e2f5e2a863e5ad2c7c6658666c61 1517 SMART SM00487 22 244 3.3E-32 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain CAK77_RS18185 4771e2f5e2a863e5ad2c7c6658666c61 1517 Gene3D G3DSA:3.40.50.300 348 433 4.8E-27 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS18185 4771e2f5e2a863e5ad2c7c6658666c61 1517 Gene3D G3DSA:3.40.50.300 285 312 4.8E-27 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS18185 4771e2f5e2a863e5ad2c7c6658666c61 1517 SUPERFAMILY SSF52540 37 217 4.97E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS18185 4771e2f5e2a863e5ad2c7c6658666c61 1517 SUPERFAMILY SSF52540 348 421 4.97E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS18185 4771e2f5e2a863e5ad2c7c6658666c61 1517 SUPERFAMILY SSF52540 261 312 4.97E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS18185 4771e2f5e2a863e5ad2c7c6658666c61 1517 Pfam PF00270 DEAD/DEAH box helicase 27 215 2.8E-27 T 06-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CAK77_RS18185 4771e2f5e2a863e5ad2c7c6658666c61 1517 Gene3D G3DSA:3.40.50.300 15 213 7.3E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS18185 4771e2f5e2a863e5ad2c7c6658666c61 1517 Pfam PF08494 DEAD/H associated 681 869 1.6E-71 T 06-07-2017 IPR013701 DEAD/H associated GO:0005524|GO:0016818 CAK77_RS18185 4771e2f5e2a863e5ad2c7c6658666c61 1517 SMART SM00490 300 417 4.0E-14 T 06-07-2017 IPR001650 Helicase, C-terminal CAK77_RS18185 4771e2f5e2a863e5ad2c7c6658666c61 1517 Pfam PF06224 Winged helix DNA-binding domain 914 1117 1.9E-7 T 06-07-2017 IPR009351 Protein of unknown function DUF1006 CAK77_RS15485 36382c97d4dbc5c17c8e88e6a2c0ba4d 188 Pfam PF14081 Domain of unknown function (DUF4262) 32 162 7.9E-38 T 06-07-2017 IPR025358 Protein of unknown function DUF4262 CAK77_RS11710 cbe982c956d4c86e4e8bc4e6aa9df290 478 SMART SM00116 98 148 0.92 T 06-07-2017 IPR000644 CBS domain CAK77_RS11710 cbe982c956d4c86e4e8bc4e6aa9df290 478 SMART SM00116 156 204 8.3 T 06-07-2017 IPR000644 CBS domain CAK77_RS11710 cbe982c956d4c86e4e8bc4e6aa9df290 478 Gene3D G3DSA:3.20.20.70 11 473 2.5E-131 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK77_RS11710 cbe982c956d4c86e4e8bc4e6aa9df290 478 SUPERFAMILY SSF54631 92 202 6.7E-16 T 06-07-2017 CAK77_RS11710 cbe982c956d4c86e4e8bc4e6aa9df290 478 SMART SM01240 11 474 2.6E-186 T 06-07-2017 CAK77_RS11710 cbe982c956d4c86e4e8bc4e6aa9df290 478 SUPERFAMILY SSF51412 202 472 2.62E-91 T 06-07-2017 CAK77_RS11710 cbe982c956d4c86e4e8bc4e6aa9df290 478 SUPERFAMILY SSF51412 11 93 2.62E-91 T 06-07-2017 CAK77_RS11710 cbe982c956d4c86e4e8bc4e6aa9df290 478 TIGRFAM TIGR01303 IMP_DH_rel_1: IMP dehydrogenase family protein 2 475 2.1E-251 T 06-07-2017 IPR005991 IMP dehydrogenase-related 1 CAK77_RS11710 cbe982c956d4c86e4e8bc4e6aa9df290 478 Pfam PF00571 CBS domain 98 137 2.2E-6 T 06-07-2017 IPR000644 CBS domain CAK77_RS11710 cbe982c956d4c86e4e8bc4e6aa9df290 478 Pfam PF00571 CBS domain 149 202 0.0039 T 06-07-2017 IPR000644 CBS domain CAK77_RS11710 cbe982c956d4c86e4e8bc4e6aa9df290 478 PIRSF PIRSF000130 2 478 8.2E-143 T 06-07-2017 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CAK77_RS11710 cbe982c956d4c86e4e8bc4e6aa9df290 478 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 13 473 7.5E-103 T 06-07-2017 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 CAK77_RS24210 338493d744878e9bb1bd7b0279950701 221 SUPERFAMILY SSF51735 3 209 5.14E-51 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS24210 338493d744878e9bb1bd7b0279950701 221 Pfam PF00106 short chain dehydrogenase 3 182 1.6E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS24210 338493d744878e9bb1bd7b0279950701 221 Gene3D G3DSA:3.40.50.720 3 216 1.3E-52 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS24210 338493d744878e9bb1bd7b0279950701 221 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2 173 0.0082 T 06-07-2017 CAK77_RS24210 338493d744878e9bb1bd7b0279950701 221 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 113 129 1.7E-21 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS24210 338493d744878e9bb1bd7b0279950701 221 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 67 78 1.7E-21 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS24210 338493d744878e9bb1bd7b0279950701 221 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 175 1.7E-21 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS24210 338493d744878e9bb1bd7b0279950701 221 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 1.7E-21 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS24210 338493d744878e9bb1bd7b0279950701 221 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 139 158 1.7E-21 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS24210 338493d744878e9bb1bd7b0279950701 221 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 126 154 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK77_RS07185 087d492a0fdd27b980268518ed84489b 550 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 11 550 3.8E-127 T 06-07-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CAK77_RS07185 087d492a0fdd27b980268518ed84489b 550 Hamap MF_00123 Arginine--tRNA ligase [argS]. 8 550 26.127 T 06-07-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CAK77_RS07185 087d492a0fdd27b980268518ed84489b 550 PRINTS PR01038 Arginyl-tRNA synthetase signature 122 137 1.3E-23 T 06-07-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CAK77_RS07185 087d492a0fdd27b980268518ed84489b 550 PRINTS PR01038 Arginyl-tRNA synthetase signature 137 153 1.3E-23 T 06-07-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CAK77_RS07185 087d492a0fdd27b980268518ed84489b 550 PRINTS PR01038 Arginyl-tRNA synthetase signature 161 174 1.3E-23 T 06-07-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CAK77_RS07185 087d492a0fdd27b980268518ed84489b 550 PRINTS PR01038 Arginyl-tRNA synthetase signature 298 319 1.3E-23 T 06-07-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CAK77_RS07185 087d492a0fdd27b980268518ed84489b 550 Gene3D G3DSA:1.10.730.10 434 550 7.1E-44 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK77_RS07185 087d492a0fdd27b980268518ed84489b 550 Gene3D G3DSA:3.30.1360.70 3 112 4.6E-27 T 06-07-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CAK77_RS07185 087d492a0fdd27b980268518ed84489b 550 SMART SM00836 429 550 4.7E-53 T 06-07-2017 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 CAK77_RS07185 087d492a0fdd27b980268518ed84489b 550 SUPERFAMILY SSF47323 423 550 3.79E-36 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK77_RS07185 087d492a0fdd27b980268518ed84489b 550 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 31 93 9.2E-20 T 06-07-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CAK77_RS07185 087d492a0fdd27b980268518ed84489b 550 SUPERFAMILY SSF52374 121 439 1.42E-82 T 06-07-2017 CAK77_RS07185 087d492a0fdd27b980268518ed84489b 550 SMART SM01016 4 93 4.7E-31 T 06-07-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CAK77_RS07185 087d492a0fdd27b980268518ed84489b 550 SUPERFAMILY SSF55190 5 113 1.44E-21 T 06-07-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CAK77_RS07185 087d492a0fdd27b980268518ed84489b 550 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 132 141 - T 06-07-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK77_RS07185 087d492a0fdd27b980268518ed84489b 550 Gene3D G3DSA:3.40.50.620 119 433 1.2E-93 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS07185 087d492a0fdd27b980268518ed84489b 550 Pfam PF05746 DALR anticodon binding domain 429 550 3.3E-38 T 06-07-2017 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 CAK77_RS07185 087d492a0fdd27b980268518ed84489b 550 Pfam PF00750 tRNA synthetases class I (R) 102 391 7.9E-22 T 06-07-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CAK77_RS12590 86ff17962937d53e73ad17814fe59290 238 PIRSF PIRSF005902 11 223 2.5E-24 T 06-07-2017 IPR001130 TatD family GO:0016788 CAK77_RS12590 86ff17962937d53e73ad17814fe59290 238 SUPERFAMILY SSF51556 23 217 4.3E-30 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK77_RS12590 86ff17962937d53e73ad17814fe59290 238 Pfam PF01026 TatD related DNase 24 217 3.1E-27 T 06-07-2017 IPR001130 TatD family GO:0016788 CAK77_RS12590 86ff17962937d53e73ad17814fe59290 238 Gene3D G3DSA:3.20.20.140 21 217 9.6E-29 T 06-07-2017 CAK77_RS24095 c7fd6d17f3ada332f4c668ea6d1d96f4 96 Pfam PF01250 Ribosomal protein S6 3 92 1.8E-26 T 06-07-2017 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS24095 c7fd6d17f3ada332f4c668ea6d1d96f4 96 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 95 20.333 T 06-07-2017 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 CAK77_RS24095 c7fd6d17f3ada332f4c668ea6d1d96f4 96 SUPERFAMILY SSF54995 1 94 1.27E-30 T 06-07-2017 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS24095 c7fd6d17f3ada332f4c668ea6d1d96f4 96 ProSitePatterns PS01048 Ribosomal protein S6 signature. 44 53 - T 06-07-2017 IPR020815 Ribosomal protein S6, conserved site GO:0003735|GO:0005840|GO:0006412|GO:0019843 CAK77_RS24095 c7fd6d17f3ada332f4c668ea6d1d96f4 96 Gene3D G3DSA:3.30.70.60 1 93 3.6E-32 T 06-07-2017 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 CAK77_RS24095 c7fd6d17f3ada332f4c668ea6d1d96f4 96 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 93 2.5E-24 T 06-07-2017 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS10470 1e15f8433690e0fef5016bf1b6288602 466 PRINTS PR00385 P450 superfamily signature 405 414 2.3E-9 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS10470 1e15f8433690e0fef5016bf1b6288602 466 PRINTS PR00385 P450 superfamily signature 283 300 2.3E-9 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS10470 1e15f8433690e0fef5016bf1b6288602 466 PRINTS PR00385 P450 superfamily signature 334 345 2.3E-9 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS10470 1e15f8433690e0fef5016bf1b6288602 466 PRINTS PR00385 P450 superfamily signature 414 425 2.3E-9 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS10470 1e15f8433690e0fef5016bf1b6288602 466 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 407 416 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CAK77_RS10470 1e15f8433690e0fef5016bf1b6288602 466 Pfam PF00067 Cytochrome P450 44 442 3.6E-69 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS10470 1e15f8433690e0fef5016bf1b6288602 466 SUPERFAMILY SSF48264 18 466 6.29E-87 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS10470 1e15f8433690e0fef5016bf1b6288602 466 Gene3D G3DSA:1.10.630.10 23 462 9.6E-89 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS10470 1e15f8433690e0fef5016bf1b6288602 466 PRINTS PR00463 E-class P450 group I signature 372 396 4.1E-28 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS10470 1e15f8433690e0fef5016bf1b6288602 466 PRINTS PR00463 E-class P450 group I signature 404 414 4.1E-28 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS10470 1e15f8433690e0fef5016bf1b6288602 466 PRINTS PR00463 E-class P450 group I signature 272 289 4.1E-28 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS10470 1e15f8433690e0fef5016bf1b6288602 466 PRINTS PR00463 E-class P450 group I signature 414 437 4.1E-28 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS10470 1e15f8433690e0fef5016bf1b6288602 466 PRINTS PR00463 E-class P450 group I signature 53 72 4.1E-28 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS10470 1e15f8433690e0fef5016bf1b6288602 466 PRINTS PR00463 E-class P450 group I signature 292 318 4.1E-28 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS20325 610b8b52790395473812c0ca9186d96c 443 TIGRFAM TIGR03449 mycothiol_MshA: D-inositol-3-phosphate glycosyltransferase 19 415 4.7E-195 T 06-07-2017 IPR017814 Mycothiol biosynthesis protein, MshA GO:0008375|GO:0010125 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 CAK77_RS20325 610b8b52790395473812c0ca9186d96c 443 Pfam PF00534 Glycosyl transferases group 1 227 381 9.1E-35 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 CAK77_RS20325 610b8b52790395473812c0ca9186d96c 443 Gene3D G3DSA:3.40.50.2000 200 380 1.2E-43 T 06-07-2017 CAK77_RS20325 610b8b52790395473812c0ca9186d96c 443 Hamap MF_01695 D-inositol-3-phosphate glycosyltransferase [mshA]. 18 418 50.213 T 06-07-2017 IPR017814 Mycothiol biosynthesis protein, MshA GO:0008375|GO:0010125 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 CAK77_RS20325 610b8b52790395473812c0ca9186d96c 443 Pfam PF13439 Glycosyltransferase Family 4 38 218 6.2E-30 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 CAK77_RS20325 610b8b52790395473812c0ca9186d96c 443 SUPERFAMILY SSF53756 19 413 7.33E-81 T 06-07-2017 CAK77_RS10905 c5c5444d489de3c06df7c50d2e955ef8 381 SUPERFAMILY SSF54373 177 280 2.08E-27 T 06-07-2017 CAK77_RS10905 c5c5444d489de3c06df7c50d2e955ef8 381 Gene3D G3DSA:3.50.50.60 5 179 8.0E-41 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS10905 c5c5444d489de3c06df7c50d2e955ef8 381 Gene3D G3DSA:3.50.50.60 276 356 8.0E-41 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS10905 c5c5444d489de3c06df7c50d2e955ef8 381 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 3.1E-17 T 06-07-2017 CAK77_RS10905 c5c5444d489de3c06df7c50d2e955ef8 381 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 152 167 3.1E-17 T 06-07-2017 CAK77_RS10905 c5c5444d489de3c06df7c50d2e955ef8 381 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 304 320 3.1E-17 T 06-07-2017 CAK77_RS10905 c5c5444d489de3c06df7c50d2e955ef8 381 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 289 304 3.1E-17 T 06-07-2017 CAK77_RS10905 c5c5444d489de3c06df7c50d2e955ef8 381 SUPERFAMILY SSF51905 6 173 8.17E-58 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS10905 c5c5444d489de3c06df7c50d2e955ef8 381 SUPERFAMILY SSF51905 276 365 8.17E-58 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS10905 c5c5444d489de3c06df7c50d2e955ef8 381 Pfam PF01494 FAD binding domain 6 350 2.8E-22 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 CAK77_RS16265 f254ed8721bbd69edaa1e6393fba2b44 1127 TIGRFAM TIGR01235 pyruv_carbox: pyruvate carboxylase 4 1126 0.0 T 06-07-2017 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 CAK77_RS16265 f254ed8721bbd69edaa1e6393fba2b44 1127 SUPERFAMILY SSF51230 1051 1126 3.93E-15 T 06-07-2017 IPR011053 Single hybrid motif CAK77_RS16265 f254ed8721bbd69edaa1e6393fba2b44 1127 Pfam PF00682 HMGL-like 524 796 8.8E-27 T 06-07-2017 IPR000891 Pyruvate carboxyltransferase GO:0003824 CAK77_RS16265 f254ed8721bbd69edaa1e6393fba2b44 1127 SUPERFAMILY SSF51246 333 451 1.15E-39 T 06-07-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAK77_RS16265 f254ed8721bbd69edaa1e6393fba2b44 1127 SUPERFAMILY SSF51569 518 828 3.66E-76 T 06-07-2017 CAK77_RS16265 f254ed8721bbd69edaa1e6393fba2b44 1127 Gene3D G3DSA:3.20.20.70 502 811 3.6E-126 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK77_RS16265 f254ed8721bbd69edaa1e6393fba2b44 1127 Pfam PF02436 Conserved carboxylase domain 820 1009 5.3E-55 T 06-07-2017 IPR003379 Carboxylase, conserved domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 CAK77_RS16265 f254ed8721bbd69edaa1e6393fba2b44 1127 SUPERFAMILY SSF89000 825 993 2.47E-40 T 06-07-2017 CAK77_RS16265 f254ed8721bbd69edaa1e6393fba2b44 1127 Gene3D G3DSA:3.30.1490.20 131 201 5.3E-23 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CAK77_RS16265 f254ed8721bbd69edaa1e6393fba2b44 1127 SMART SM00878 339 445 5.5E-58 T 06-07-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAK77_RS16265 f254ed8721bbd69edaa1e6393fba2b44 1127 SUPERFAMILY SSF52440 1 112 5.61E-41 T 06-07-2017 IPR016185 Pre-ATP-grasp domain CAK77_RS16265 f254ed8721bbd69edaa1e6393fba2b44 1127 SUPERFAMILY SSF56059 84 361 8.49E-68 T 06-07-2017 CAK77_RS16265 f254ed8721bbd69edaa1e6393fba2b44 1127 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CAK77_RS16265 f254ed8721bbd69edaa1e6393fba2b44 1127 Gene3D G3DSA:3.40.50.20 1 130 2.0E-45 T 06-07-2017 IPR016185 Pre-ATP-grasp domain CAK77_RS16265 f254ed8721bbd69edaa1e6393fba2b44 1127 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 117 323 7.4E-70 T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CAK77_RS16265 f254ed8721bbd69edaa1e6393fba2b44 1127 Pfam PF02785 Biotin carboxylase C-terminal domain 339 446 2.8E-36 T 06-07-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAK77_RS16265 f254ed8721bbd69edaa1e6393fba2b44 1127 Pfam PF00364 Biotin-requiring enzyme 1068 1126 1.1E-12 T 06-07-2017 IPR000089 Biotin/lipoyl attachment CAK77_RS16265 f254ed8721bbd69edaa1e6393fba2b44 1127 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 1083 1100 - T 06-07-2017 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAK77_RS16265 f254ed8721bbd69edaa1e6393fba2b44 1127 Gene3D G3DSA:3.10.600.10 961 1048 2.3E-31 T 06-07-2017 CAK77_RS16265 f254ed8721bbd69edaa1e6393fba2b44 1127 PIRSF PIRSF001594 1 1127 0.0 T 06-07-2017 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 CAK77_RS16265 f254ed8721bbd69edaa1e6393fba2b44 1127 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 111 1.4E-39 T 06-07-2017 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAK77_RS16265 f254ed8721bbd69edaa1e6393fba2b44 1127 Gene3D G3DSA:2.40.50.100 1052 1126 7.5E-19 T 06-07-2017 CAK77_RS16265 f254ed8721bbd69edaa1e6393fba2b44 1127 Gene3D G3DSA:3.30.470.20 205 451 2.9E-100 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAK77_RS19160 cca93ce8900a73b500d3ddb7affef98b 150 Gene3D G3DSA:1.10.10.10 1 54 8.7E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS19160 cca93ce8900a73b500d3ddb7affef98b 150 Gene3D G3DSA:3.30.70.920 57 137 2.2E-18 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CAK77_RS19160 cca93ce8900a73b500d3ddb7affef98b 150 SMART SM00344 4 111 7.0E-37 T 06-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CAK77_RS19160 cca93ce8900a73b500d3ddb7affef98b 150 ProSitePatterns PS00519 AsnC-type HTH domain signature. 22 48 - T 06-07-2017 IPR019885 Transcription regulator HTH, AsnC-type, conserved site CAK77_RS19160 cca93ce8900a73b500d3ddb7affef98b 150 Pfam PF13404 AsnC-type helix-turn-helix domain 4 44 5.2E-16 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAK77_RS19160 cca93ce8900a73b500d3ddb7affef98b 150 SUPERFAMILY SSF46785 4 64 2.69E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS19160 cca93ce8900a73b500d3ddb7affef98b 150 SUPERFAMILY SSF54909 64 146 3.08E-15 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAK77_RS19160 cca93ce8900a73b500d3ddb7affef98b 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 20 31 2.8E-10 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAK77_RS19160 cca93ce8900a73b500d3ddb7affef98b 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 4 20 2.8E-10 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAK77_RS19160 cca93ce8900a73b500d3ddb7affef98b 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 31 50 2.8E-10 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAK77_RS19160 cca93ce8900a73b500d3ddb7affef98b 150 Pfam PF01037 Lrp/AsnC ligand binding domain 72 140 1.6E-14 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CAK77_RS22615 bda016f14b14853ee4a38306d0474d22 457 SUPERFAMILY SSF52777 69 151 5.67E-7 T 06-07-2017 CAK77_RS22615 bda016f14b14853ee4a38306d0474d22 457 TIGRFAM TIGR02946 acyl_WS_DGAT: acyltransferase, WS/DGAT/MGAT 7 454 8.9E-143 T 06-07-2017 IPR014292 Acyltransferase, WS/DGAT/MGAT GO:0016746|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CAK77_RS22615 bda016f14b14853ee4a38306d0474d22 457 Pfam PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain 7 267 1.6E-77 T 06-07-2017 IPR004255 O-acyltransferase, WSD1, N-terminal GO:0004144|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CAK77_RS22615 bda016f14b14853ee4a38306d0474d22 457 SUPERFAMILY SSF52777 242 454 1.78E-5 T 06-07-2017 CAK77_RS22615 bda016f14b14853ee4a38306d0474d22 457 Pfam PF06974 Protein of unknown function (DUF1298) 307 452 1.3E-32 T 06-07-2017 IPR009721 O-acyltransferase WSD1, C-terminal GO:0004144 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CAK77_RS23375 286995efa6fe84b11238d3ea4ed9332d 425 SUPERFAMILY SSF53756 1 417 2.74E-82 T 06-07-2017 CAK77_RS23375 286995efa6fe84b11238d3ea4ed9332d 425 Gene3D G3DSA:3.40.50.2000 1 254 9.3E-57 T 06-07-2017 CAK77_RS23375 286995efa6fe84b11238d3ea4ed9332d 425 Gene3D G3DSA:3.40.50.2000 255 398 6.6E-47 T 06-07-2017 CAK77_RS23375 286995efa6fe84b11238d3ea4ed9332d 425 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 3 94 1.8E-8 T 06-07-2017 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CAK77_RS05665 4d9002504548bb391b6bb5bbd8319175 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 1.1E-15 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS05665 4d9002504548bb391b6bb5bbd8319175 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 186 1.1E-15 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS05665 4d9002504548bb391b6bb5bbd8319175 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 20 37 1.1E-15 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS05665 4d9002504548bb391b6bb5bbd8319175 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 190 207 1.1E-15 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS05665 4d9002504548bb391b6bb5bbd8319175 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 1.1E-15 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS05665 4d9002504548bb391b6bb5bbd8319175 294 SUPERFAMILY SSF51735 15 243 7.6E-53 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS05665 4d9002504548bb391b6bb5bbd8319175 294 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 167 186 1.2E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS05665 4d9002504548bb391b6bb5bbd8319175 294 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 1.2E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS05665 4d9002504548bb391b6bb5bbd8319175 294 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 87 98 1.2E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS05665 4d9002504548bb391b6bb5bbd8319175 294 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 19 204 0.0014 T 06-07-2017 CAK77_RS05665 4d9002504548bb391b6bb5bbd8319175 294 Gene3D G3DSA:3.40.50.720 16 242 1.1E-56 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS05665 4d9002504548bb391b6bb5bbd8319175 294 Pfam PF00106 short chain dehydrogenase 20 209 7.0E-27 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS19380 7b9f7711ed78ef115771d7d038af6986 481 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 370 382 1.9E-28 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 CAK77_RS19380 7b9f7711ed78ef115771d7d038af6986 481 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 36 46 1.9E-28 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 CAK77_RS19380 7b9f7711ed78ef115771d7d038af6986 481 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 98 110 1.9E-28 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 CAK77_RS19380 7b9f7711ed78ef115771d7d038af6986 481 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 340 346 1.9E-28 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 CAK77_RS19380 7b9f7711ed78ef115771d7d038af6986 481 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 23 35 1.9E-28 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 CAK77_RS19380 7b9f7711ed78ef115771d7d038af6986 481 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 52 64 1.9E-28 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 CAK77_RS19380 7b9f7711ed78ef115771d7d038af6986 481 SUPERFAMILY SSF51905 24 350 4.96E-32 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS19380 7b9f7711ed78ef115771d7d038af6986 481 ProSitePatterns PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1. 28 45 - T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 CAK77_RS19380 7b9f7711ed78ef115771d7d038af6986 481 Gene3D G3DSA:3.50.50.60 24 127 4.1E-33 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS19380 7b9f7711ed78ef115771d7d038af6986 481 Gene3D G3DSA:3.50.50.60 160 342 4.1E-33 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS19380 7b9f7711ed78ef115771d7d038af6986 481 Pfam PF01266 FAD dependent oxidoreductase 24 381 2.0E-45 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CAK77_RS19380 7b9f7711ed78ef115771d7d038af6986 481 ProSitePatterns PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2. 375 385 - T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 CAK77_RS18765 ebf0e8c679689fd37268b6bfa66f419e 350 SUPERFAMILY SSF103481 51 144 1.96E-11 T 06-07-2017 CAK77_RS18765 ebf0e8c679689fd37268b6bfa66f419e 350 Pfam PF00892 EamA-like transporter family 9 144 3.5E-14 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAK77_RS18765 ebf0e8c679689fd37268b6bfa66f419e 350 Pfam PF00892 EamA-like transporter family 156 299 4.6E-16 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAK77_RS18765 ebf0e8c679689fd37268b6bfa66f419e 350 SUPERFAMILY SSF103481 223 304 3.14E-12 T 06-07-2017 CAK77_RS08160 ca518d036abd38c19192630f9a5a7934 110 Pfam PF06737 Transglycosylase-like domain 34 106 6.2E-34 T 06-07-2017 IPR010618 Transglycosylase-like CAK77_RS08160 ca518d036abd38c19192630f9a5a7934 110 SUPERFAMILY SSF53955 33 109 1.07E-32 T 06-07-2017 IPR023346 Lysozyme-like domain CAK77_RS08160 ca518d036abd38c19192630f9a5a7934 110 Gene3D G3DSA:1.10.530.10 20 109 8.0E-40 T 06-07-2017 CAK77_RS22985 731fff0381df4535ef74d98ebbbeeb08 305 Gene3D G3DSA:3.20.20.60 13 294 2.0E-92 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAK77_RS22985 731fff0381df4535ef74d98ebbbeeb08 305 TIGRFAM TIGR02317 prpB: methylisocitrate lyase 15 297 2.3E-124 T 06-07-2017 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 CAK77_RS22985 731fff0381df4535ef74d98ebbbeeb08 305 ProSitePatterns PS00161 Isocitrate lyase signature. 127 132 - T 06-07-2017 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824|GO:0008152 CAK77_RS22985 731fff0381df4535ef74d98ebbbeeb08 305 SUPERFAMILY SSF51621 5 298 3.41E-96 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAK77_RS22985 731fff0381df4535ef74d98ebbbeeb08 305 Pfam PF13714 Phosphoenolpyruvate phosphomutase 18 260 4.6E-50 T 06-07-2017 CAK77_RS22985 731fff0381df4535ef74d98ebbbeeb08 305 Hamap MF_01939 2-methylisocitrate lyase [prpB]. 12 298 47.226 T 06-07-2017 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 CAK77_RS10555 06a3ceef711928bd2e137c0234d55707 352 Pfam PF00155 Aminotransferase class I and II 12 289 1.4E-38 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAK77_RS10555 06a3ceef711928bd2e137c0234d55707 352 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 201 210 - T 06-07-2017 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 CAK77_RS10555 06a3ceef711928bd2e137c0234d55707 352 SUPERFAMILY SSF53383 11 334 1.01E-66 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK77_RS10555 06a3ceef711928bd2e137c0234d55707 352 Gene3D G3DSA:3.90.1150.10 233 332 1.7E-18 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK77_RS10555 06a3ceef711928bd2e137c0234d55707 352 Gene3D G3DSA:3.40.640.10 24 232 2.8E-57 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK77_RS07615 84ac165405229e04630751869f8e388f 3092 PRINTS PR01483 Fatty acid synthase signature 416 436 3.1E-110 T 06-07-2017 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 CAK77_RS07615 84ac165405229e04630751869f8e388f 3092 PRINTS PR01483 Fatty acid synthase signature 737 755 3.1E-110 T 06-07-2017 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 CAK77_RS07615 84ac165405229e04630751869f8e388f 3092 PRINTS PR01483 Fatty acid synthase signature 1254 1275 3.1E-110 T 06-07-2017 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 CAK77_RS07615 84ac165405229e04630751869f8e388f 3092 PRINTS PR01483 Fatty acid synthase signature 567 586 3.1E-110 T 06-07-2017 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 CAK77_RS07615 84ac165405229e04630751869f8e388f 3092 PRINTS PR01483 Fatty acid synthase signature 442 460 3.1E-110 T 06-07-2017 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 CAK77_RS07615 84ac165405229e04630751869f8e388f 3092 PRINTS PR01483 Fatty acid synthase signature 547 565 3.1E-110 T 06-07-2017 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 CAK77_RS07615 84ac165405229e04630751869f8e388f 3092 PRINTS PR01483 Fatty acid synthase signature 1339 1358 3.1E-110 T 06-07-2017 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 CAK77_RS07615 84ac165405229e04630751869f8e388f 3092 PRINTS PR01483 Fatty acid synthase signature 1441 1460 3.1E-110 T 06-07-2017 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 CAK77_RS07615 84ac165405229e04630751869f8e388f 3092 PRINTS PR01483 Fatty acid synthase signature 1360 1383 3.1E-110 T 06-07-2017 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 CAK77_RS07615 84ac165405229e04630751869f8e388f 3092 PRINTS PR01483 Fatty acid synthase signature 1232 1254 3.1E-110 T 06-07-2017 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 CAK77_RS07615 84ac165405229e04630751869f8e388f 3092 PRINTS PR01483 Fatty acid synthase signature 1477 1498 3.1E-110 T 06-07-2017 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 CAK77_RS07615 84ac165405229e04630751869f8e388f 3092 PRINTS PR01483 Fatty acid synthase signature 847 871 3.1E-110 T 06-07-2017 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 CAK77_RS07615 84ac165405229e04630751869f8e388f 3092 Gene3D G3DSA:3.10.129.10 1180 1343 2.2E-33 T 06-07-2017 IPR029069 HotDog domain CAK77_RS07615 84ac165405229e04630751869f8e388f 3092 Gene3D G3DSA:3.40.47.10 2848 3001 1.9E-29 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS07615 84ac165405229e04630751869f8e388f 3092 SMART SM00825 Beta-ketoacyl synthase 2594 3002 3.2E-4 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAK77_RS07615 84ac165405229e04630751869f8e388f 3092 SUPERFAMILY SSF53901 2798 3012 6.14E-35 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS07615 84ac165405229e04630751869f8e388f 3092 Gene3D G3DSA:3.40.366.10 289 380 8.9E-24 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAK77_RS07615 84ac165405229e04630751869f8e388f 3092 Gene3D G3DSA:3.40.366.10 36 190 8.9E-24 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAK77_RS07615 84ac165405229e04630751869f8e388f 3092 Gene3D G3DSA:3.40.366.10 1666 1733 5.6E-45 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAK77_RS07615 84ac165405229e04630751869f8e388f 3092 Gene3D G3DSA:3.40.366.10 1576 1630 5.6E-45 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAK77_RS07615 84ac165405229e04630751869f8e388f 3092 Gene3D G3DSA:3.40.366.10 1344 1484 5.6E-45 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAK77_RS07615 84ac165405229e04630751869f8e388f 3092 Gene3D G3DSA:3.40.47.10 2462 2500 9.3E-35 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS07615 84ac165405229e04630751869f8e388f 3092 Gene3D G3DSA:3.40.47.10 2617 2840 9.3E-35 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS07615 84ac165405229e04630751869f8e388f 3092 SUPERFAMILY SSF52151 291 376 5.49E-19 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAK77_RS07615 84ac165405229e04630751869f8e388f 3092 SUPERFAMILY SSF52151 41 193 5.49E-19 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAK77_RS07615 84ac165405229e04630751869f8e388f 3092 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2837 2962 9.2E-28 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAK77_RS07615 84ac165405229e04630751869f8e388f 3092 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1350 1807 1.2E-4 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain CAK77_RS07615 84ac165405229e04630751869f8e388f 3092 Pfam PF00698 Acyl transferase domain 1348 1554 1.0E-35 T 06-07-2017 IPR014043 Acyl transferase CAK77_RS07615 84ac165405229e04630751869f8e388f 3092 Pfam PF08354 Domain of unknown function (DUF1729) 853 905 3.1E-20 T 06-07-2017 IPR013565 Domain of unknown function DUF1729 GO:0004318|GO:0055114 KEGG: 00061+4.2.1.59+2.3.1.39+1.3.1.9+3.1.2.14|KEGG: 00780+4.2.1.59|MetaCyc: PWY-4381|MetaCyc: PWY-5142|MetaCyc: PWY-5147|MetaCyc: PWY-5366|MetaCyc: PWY-5367|MetaCyc: PWY-5966|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-6799|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7723|MetaCyc: PWYG-321 CAK77_RS07615 84ac165405229e04630751869f8e388f 3092 SUPERFAMILY SSF51735 2133 2387 3.41E-11 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS07615 84ac165405229e04630751869f8e388f 3092 Pfam PF01575 MaoC like domain 1216 1332 1.2E-24 T 06-07-2017 IPR002539 MaoC-like domain CAK77_RS07615 84ac165405229e04630751869f8e388f 3092 Gene3D G3DSA:3.40.50.720 2128 2380 2.6E-8 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS07615 84ac165405229e04630751869f8e388f 3092 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2590 2827 2.1E-36 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAK77_RS07615 84ac165405229e04630751869f8e388f 3092 SUPERFAMILY SSF52151 1636 1728 7.32E-31 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAK77_RS07615 84ac165405229e04630751869f8e388f 3092 SUPERFAMILY SSF52151 1346 1490 7.32E-31 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAK77_RS07615 84ac165405229e04630751869f8e388f 3092 SUPERFAMILY SSF52151 1578 1599 7.32E-31 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAK77_RS07615 84ac165405229e04630751869f8e388f 3092 SUPERFAMILY SSF53901 2607 2836 2.52E-31 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS07615 84ac165405229e04630751869f8e388f 3092 Gene3D G3DSA:3.20.20.70 400 703 3.9E-27 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK77_RS07615 84ac165405229e04630751869f8e388f 3092 SUPERFAMILY SSF51412 400 666 2.2E-19 T 06-07-2017 CAK77_RS07615 84ac165405229e04630751869f8e388f 3092 SUPERFAMILY SSF54637 1226 1341 4.83E-21 T 06-07-2017 IPR029069 HotDog domain CAK77_RS11230 c6bf8121ed756015b7ec1d824a7d090b 719 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 27 707 0.0 T 06-07-2017 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 CAK77_RS11230 c6bf8121ed756015b7ec1d824a7d090b 719 Pfam PF00271 Helicase conserved C-terminal domain 454 567 5.8E-19 T 06-07-2017 IPR001650 Helicase, C-terminal CAK77_RS11230 c6bf8121ed756015b7ec1d824a7d090b 719 Pfam PF02151 UvrB/uvrC motif 676 709 8.6E-8 T 06-07-2017 IPR001943 UVR domain GO:0005515 CAK77_RS11230 c6bf8121ed756015b7ec1d824a7d090b 719 Gene3D G3DSA:4.10.860.10 663 712 1.4E-14 T 06-07-2017 IPR001943 UVR domain GO:0005515 CAK77_RS11230 c6bf8121ed756015b7ec1d824a7d090b 719 SUPERFAMILY SSF52540 28 437 3.92E-128 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS11230 c6bf8121ed756015b7ec1d824a7d090b 719 Gene3D G3DSA:3.30.2060.10 182 250 1.9E-11 T 06-07-2017 CAK77_RS11230 c6bf8121ed756015b7ec1d824a7d090b 719 SUPERFAMILY SSF46600 664 711 4.71E-11 T 06-07-2017 IPR001943 UVR domain GO:0005515 CAK77_RS11230 c6bf8121ed756015b7ec1d824a7d090b 719 Pfam PF04851 Type III restriction enzyme, res subunit 38 161 4.4E-8 T 06-07-2017 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CAK77_RS11230 c6bf8121ed756015b7ec1d824a7d090b 719 Gene3D G3DSA:3.40.50.300 441 603 4.0E-40 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS11230 c6bf8121ed756015b7ec1d824a7d090b 719 Gene3D G3DSA:3.40.50.300 410 431 2.5E-49 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS11230 c6bf8121ed756015b7ec1d824a7d090b 719 Gene3D G3DSA:3.40.50.300 29 112 2.5E-49 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS11230 c6bf8121ed756015b7ec1d824a7d090b 719 Gene3D G3DSA:3.40.50.300 300 360 2.5E-49 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS11230 c6bf8121ed756015b7ec1d824a7d090b 719 Pfam PF12344 Ultra-violet resistance protein B 574 615 3.6E-21 T 06-07-2017 IPR024759 UvrB, YAD/RRR-motif-containing domain CAK77_RS11230 c6bf8121ed756015b7ec1d824a7d090b 719 SMART SM00490 482 568 3.4E-18 T 06-07-2017 IPR001650 Helicase, C-terminal CAK77_RS11230 c6bf8121ed756015b7ec1d824a7d090b 719 SUPERFAMILY SSF52540 481 602 1.05E-34 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS11230 c6bf8121ed756015b7ec1d824a7d090b 719 SUPERFAMILY SSF52540 56 105 1.05E-34 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS11230 c6bf8121ed756015b7ec1d824a7d090b 719 SMART SM00487 32 448 5.2E-26 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain CAK77_RS11230 c6bf8121ed756015b7ec1d824a7d090b 719 Hamap MF_00204 UvrABC system protein B [uvrB]. 26 709 42.558 T 06-07-2017 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 CAK77_RS01425 3ec9d481658388950921f8eaac2ccab1 342 TIGRFAM TIGR02778 ligD_pol: DNA ligase D, polymerase domain 15 264 9.3E-66 T 06-07-2017 IPR014145 DNA ligase D, polymerase domain CAK77_RS16395 ed17b5c7d6d4a791f501804e27432a26 199 Gene3D G3DSA:3.20.19.10 3 186 2.9E-32 T 06-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CAK77_RS16395 ed17b5c7d6d4a791f501804e27432a26 199 Pfam PF00694 Aconitase C-terminal domain 3 111 9.2E-21 T 06-07-2017 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 CAK77_RS16395 ed17b5c7d6d4a791f501804e27432a26 199 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 191 36.995 T 06-07-2017 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 CAK77_RS16395 ed17b5c7d6d4a791f501804e27432a26 199 SUPERFAMILY SSF52016 3 189 1.65E-49 T 06-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CAK77_RS16395 ed17b5c7d6d4a791f501804e27432a26 199 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 2 180 4.6E-50 T 06-07-2017 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 CAK77_RS10675 73bde73a7749a2d4e7d58b083ff14edd 374 Gene3D G3DSA:3.90.230.10 144 371 9.1E-72 T 06-07-2017 IPR000994 Peptidase M24, structural domain CAK77_RS10675 73bde73a7749a2d4e7d58b083ff14edd 374 SUPERFAMILY SSF53092 4 143 7.32E-20 T 06-07-2017 IPR028980 Creatinase/Aminopeptidase P, N-terminal CAK77_RS10675 73bde73a7749a2d4e7d58b083ff14edd 374 Pfam PF01321 Creatinase/Prolidase N-terminal domain 14 145 3.7E-14 T 06-07-2017 IPR000587 Creatinase, N-terminal GO:0016787 CAK77_RS10675 73bde73a7749a2d4e7d58b083ff14edd 374 Pfam PF00557 Metallopeptidase family M24 153 355 2.6E-59 T 06-07-2017 IPR000994 Peptidase M24, structural domain CAK77_RS10675 73bde73a7749a2d4e7d58b083ff14edd 374 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 301 313 - T 06-07-2017 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site CAK77_RS10675 73bde73a7749a2d4e7d58b083ff14edd 374 Gene3D G3DSA:3.40.350.10 3 142 1.1E-18 T 06-07-2017 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal CAK77_RS10675 73bde73a7749a2d4e7d58b083ff14edd 374 SUPERFAMILY SSF55920 144 371 1.31E-71 T 06-07-2017 IPR000994 Peptidase M24, structural domain CAK77_RS12690 16d0d66a8969b759f07b838fb7bdcd34 416 Gene3D G3DSA:1.20.140.10 227 413 7.2E-57 T 06-07-2017 CAK77_RS12690 16d0d66a8969b759f07b838fb7bdcd34 416 SUPERFAMILY SSF56645 22 233 5.1E-44 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK77_RS12690 16d0d66a8969b759f07b838fb7bdcd34 416 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 26 121 2.2E-11 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS12690 16d0d66a8969b759f07b838fb7bdcd34 416 SUPERFAMILY SSF47203 252 405 1.22E-20 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS12690 16d0d66a8969b759f07b838fb7bdcd34 416 Gene3D G3DSA:2.40.110.10 135 226 1.5E-21 T 06-07-2017 CAK77_RS12690 16d0d66a8969b759f07b838fb7bdcd34 416 Gene3D G3DSA:1.10.540.10 7 116 1.6E-32 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS12690 16d0d66a8969b759f07b838fb7bdcd34 416 PIRSF PIRSF016578 2 410 1.3E-38 T 06-07-2017 CAK77_RS12690 16d0d66a8969b759f07b838fb7bdcd34 416 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 135 221 8.2E-12 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAK77_RS12690 16d0d66a8969b759f07b838fb7bdcd34 416 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 255 391 1.1E-19 T 06-07-2017 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain CAK77_RS20535 c5d4d15988f6d07ab7757f6e79c608e3 3243 Gene3D G3DSA:3.40.50.980 1912 2074 2.9E-41 T 06-07-2017 CAK77_RS20535 c5d4d15988f6d07ab7757f6e79c608e3 3243 Gene3D G3DSA:3.40.50.980 404 557 4.8E-37 T 06-07-2017 CAK77_RS20535 c5d4d15988f6d07ab7757f6e79c608e3 3243 SUPERFAMILY SSF52777 2534 2790 4.22E-25 T 06-07-2017 CAK77_RS20535 c5d4d15988f6d07ab7757f6e79c608e3 3243 SUPERFAMILY SSF47336 2263 2333 1.57E-16 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS20535 c5d4d15988f6d07ab7757f6e79c608e3 3243 Gene3D G3DSA:1.10.1200.10 2276 2335 3.9E-24 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS20535 c5d4d15988f6d07ab7757f6e79c608e3 3243 Gene3D G3DSA:1.10.1200.10 756 816 4.5E-23 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS20535 c5d4d15988f6d07ab7757f6e79c608e3 3243 SUPERFAMILY SSF52777 1007 1274 1.03E-22 T 06-07-2017 CAK77_RS20535 c5d4d15988f6d07ab7757f6e79c608e3 3243 Pfam PF13193 AMP-binding enzyme C-terminal domain 2171 2246 8.7E-11 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAK77_RS20535 c5d4d15988f6d07ab7757f6e79c608e3 3243 Pfam PF13193 AMP-binding enzyme C-terminal domain 654 725 6.8E-9 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAK77_RS20535 c5d4d15988f6d07ab7757f6e79c608e3 3243 SUPERFAMILY SSF52777 1490 1729 2.56E-51 T 06-07-2017 CAK77_RS20535 c5d4d15988f6d07ab7757f6e79c608e3 3243 SUPERFAMILY SSF47336 743 813 3.8E-15 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS20535 c5d4d15988f6d07ab7757f6e79c608e3 3243 ProSitePatterns PS00012 Phosphopantetheine attachment site. 775 790 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site CAK77_RS20535 c5d4d15988f6d07ab7757f6e79c608e3 3243 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1902 1913 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK77_RS20535 c5d4d15988f6d07ab7757f6e79c608e3 3243 Gene3D G3DSA:3.30.300.30 641 755 1.6E-35 T 06-07-2017 CAK77_RS20535 c5d4d15988f6d07ab7757f6e79c608e3 3243 Gene3D G3DSA:3.30.300.30 2159 2275 2.1E-40 T 06-07-2017 CAK77_RS20535 c5d4d15988f6d07ab7757f6e79c608e3 3243 SUPERFAMILY SSF56801 211 764 1.11E-144 T 06-07-2017 CAK77_RS20535 c5d4d15988f6d07ab7757f6e79c608e3 3243 SUPERFAMILY SSF52777 828 1017 8.0E-25 T 06-07-2017 CAK77_RS20535 c5d4d15988f6d07ab7757f6e79c608e3 3243 Pfam PF00550 Phosphopantetheine attachment site 755 813 1.4E-8 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS20535 c5d4d15988f6d07ab7757f6e79c608e3 3243 Pfam PF00550 Phosphopantetheine attachment site 2274 2333 7.0E-10 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS20535 c5d4d15988f6d07ab7757f6e79c608e3 3243 SUPERFAMILY SSF56801 1722 2284 1.7E-146 T 06-07-2017 CAK77_RS20535 c5d4d15988f6d07ab7757f6e79c608e3 3243 SUPERFAMILY SSF52777 2349 2513 9.23E-25 T 06-07-2017 CAK77_RS20535 c5d4d15988f6d07ab7757f6e79c608e3 3243 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2295 2310 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site CAK77_RS20535 c5d4d15988f6d07ab7757f6e79c608e3 3243 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 2656 2814 1.2E-31 T 06-07-2017 IPR010060 Non-ribosomal peptide synthase CAK77_RS20535 c5d4d15988f6d07ab7757f6e79c608e3 3243 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 1140 1297 1.0E-32 T 06-07-2017 IPR010060 Non-ribosomal peptide synthase CAK77_RS20535 c5d4d15988f6d07ab7757f6e79c608e3 3243 Pfam PF00501 AMP-binding enzyme 1763 2163 1.6E-87 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK77_RS20535 c5d4d15988f6d07ab7757f6e79c608e3 3243 Pfam PF00501 AMP-binding enzyme 256 646 3.2E-88 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK77_RS20535 c5d4d15988f6d07ab7757f6e79c608e3 3243 Gene3D G3DSA:3.40.50.980 1758 1911 3.5E-46 T 06-07-2017 CAK77_RS20535 c5d4d15988f6d07ab7757f6e79c608e3 3243 Pfam PF00668 Condensation domain 2821 3113 2.0E-48 T 06-07-2017 IPR001242 Condensation domain CAK77_RS20535 c5d4d15988f6d07ab7757f6e79c608e3 3243 Pfam PF00668 Condensation domain 1304 1600 8.4E-51 T 06-07-2017 IPR001242 Condensation domain CAK77_RS20535 c5d4d15988f6d07ab7757f6e79c608e3 3243 Pfam PF00668 Condensation domain 850 1124 4.4E-23 T 06-07-2017 IPR001242 Condensation domain CAK77_RS20535 c5d4d15988f6d07ab7757f6e79c608e3 3243 Pfam PF00668 Condensation domain 2370 2641 1.6E-29 T 06-07-2017 IPR001242 Condensation domain CAK77_RS20535 c5d4d15988f6d07ab7757f6e79c608e3 3243 SUPERFAMILY SSF52777 17 222 1.03E-20 T 06-07-2017 CAK77_RS20535 c5d4d15988f6d07ab7757f6e79c608e3 3243 ProSitePatterns PS00455 Putative AMP-binding domain signature. 398 409 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK77_RS20535 c5d4d15988f6d07ab7757f6e79c608e3 3243 Gene3D G3DSA:2.30.38.10 558 636 1.8E-23 T 06-07-2017 CAK77_RS20535 c5d4d15988f6d07ab7757f6e79c608e3 3243 Gene3D G3DSA:2.30.38.10 2075 2153 1.1E-20 T 06-07-2017 CAK77_RS20535 c5d4d15988f6d07ab7757f6e79c608e3 3243 Gene3D G3DSA:3.40.50.980 251 403 2.4E-47 T 06-07-2017 CAK77_RS20535 c5d4d15988f6d07ab7757f6e79c608e3 3243 SUPERFAMILY SSF52777 1301 1503 6.23E-39 T 06-07-2017 CAK77_RS20535 c5d4d15988f6d07ab7757f6e79c608e3 3243 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 277 669 5.1E-127 T 06-07-2017 IPR010071 Amino acid adenylation domain CAK77_RS20535 c5d4d15988f6d07ab7757f6e79c608e3 3243 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1784 2187 3.7E-132 T 06-07-2017 IPR010071 Amino acid adenylation domain CAK77_RS20535 c5d4d15988f6d07ab7757f6e79c608e3 3243 SUPERFAMILY SSF52777 2818 2997 4.0E-35 T 06-07-2017 CAK77_RS20535 c5d4d15988f6d07ab7757f6e79c608e3 3243 SUPERFAMILY SSF52777 3001 3234 3.45E-52 T 06-07-2017 CAK77_RS05310 6f2a60c515958f03765a945fa786d26d 389 Gene3D G3DSA:3.30.1490.20 22 87 9.9E-17 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CAK77_RS05310 6f2a60c515958f03765a945fa786d26d 389 PIRSF PIRSF001554 1 388 2.9E-134 T 06-07-2017 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CAK77_RS05310 6f2a60c515958f03765a945fa786d26d 389 Hamap MF_00558 Succinyl-CoA ligase [ADP-forming] subunit beta [sucC]. 1 386 39.38 T 06-07-2017 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CAK77_RS05310 6f2a60c515958f03765a945fa786d26d 389 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 249 273 - T 06-07-2017 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CAK77_RS05310 6f2a60c515958f03765a945fa786d26d 389 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 1 384 4.5E-121 T 06-07-2017 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CAK77_RS05310 6f2a60c515958f03765a945fa786d26d 389 Gene3D G3DSA:3.40.50.261 232 385 4.6E-51 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CAK77_RS05310 6f2a60c515958f03765a945fa786d26d 389 Gene3D G3DSA:3.30.470.20 88 230 8.8E-51 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAK77_RS05310 6f2a60c515958f03765a945fa786d26d 389 SUPERFAMILY SSF56059 1 227 1.73E-64 T 06-07-2017 CAK77_RS05310 6f2a60c515958f03765a945fa786d26d 389 Pfam PF00549 CoA-ligase 256 364 3.1E-12 T 06-07-2017 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CAK77_RS05310 6f2a60c515958f03765a945fa786d26d 389 Pfam PF08442 ATP-grasp domain 2 194 2.4E-68 T 06-07-2017 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CAK77_RS05310 6f2a60c515958f03765a945fa786d26d 389 SUPERFAMILY SSF52210 231 385 4.19E-40 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CAK77_RS11795 88658c959948903916f6dd05d9890f69 484 SUPERFAMILY SSF51905 28 366 6.62E-34 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS11795 88658c959948903916f6dd05d9890f69 484 Gene3D G3DSA:3.50.50.60 29 132 4.7E-20 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS11795 88658c959948903916f6dd05d9890f69 484 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 187 212 2.8E-9 T 06-07-2017 CAK77_RS11795 88658c959948903916f6dd05d9890f69 484 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 31 53 2.8E-9 T 06-07-2017 CAK77_RS11795 88658c959948903916f6dd05d9890f69 484 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 332 339 2.8E-9 T 06-07-2017 CAK77_RS11795 88658c959948903916f6dd05d9890f69 484 Gene3D G3DSA:3.50.50.60 133 362 1.6E-27 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS11795 88658c959948903916f6dd05d9890f69 484 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 30 355 2.2E-57 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS11795 88658c959948903916f6dd05d9890f69 484 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 317 339 3.5E-10 T 06-07-2017 CAK77_RS11795 88658c959948903916f6dd05d9890f69 484 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 127 145 3.5E-10 T 06-07-2017 CAK77_RS11795 88658c959948903916f6dd05d9890f69 484 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 187 205 3.5E-10 T 06-07-2017 CAK77_RS11795 88658c959948903916f6dd05d9890f69 484 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 32 51 3.5E-10 T 06-07-2017 CAK77_RS20460 cadbda7efa4cf824f98784ede53e0955 139 SMART SM00530 21 76 1.3E-15 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAK77_RS20460 cadbda7efa4cf824f98784ede53e0955 139 SUPERFAMILY SSF47413 16 78 1.32E-16 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK77_RS20460 cadbda7efa4cf824f98784ede53e0955 139 Pfam PF01381 Helix-turn-helix 22 75 2.2E-15 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAK77_RS20460 cadbda7efa4cf824f98784ede53e0955 139 Gene3D G3DSA:1.10.260.40 18 83 2.5E-19 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK77_RS15905 ce86b27028601351845d5c49877f7966 277 ProSitePatterns PS00963 Ribosomal protein S2 signature 2. 158 182 - T 06-07-2017 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 CAK77_RS15905 ce86b27028601351845d5c49877f7966 277 PRINTS PR00395 Ribosomal protein S2 signature 175 186 1.5E-39 T 06-07-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS15905 ce86b27028601351845d5c49877f7966 277 PRINTS PR00395 Ribosomal protein S2 signature 196 210 1.5E-39 T 06-07-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS15905 ce86b27028601351845d5c49877f7966 277 PRINTS PR00395 Ribosomal protein S2 signature 87 104 1.5E-39 T 06-07-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS15905 ce86b27028601351845d5c49877f7966 277 PRINTS PR00395 Ribosomal protein S2 signature 37 46 1.5E-39 T 06-07-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS15905 ce86b27028601351845d5c49877f7966 277 PRINTS PR00395 Ribosomal protein S2 signature 158 175 1.5E-39 T 06-07-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS15905 ce86b27028601351845d5c49877f7966 277 PRINTS PR00395 Ribosomal protein S2 signature 6 24 1.5E-39 T 06-07-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS15905 ce86b27028601351845d5c49877f7966 277 Pfam PF00318 Ribosomal protein S2 9 224 3.1E-98 T 06-07-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS15905 ce86b27028601351845d5c49877f7966 277 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 2 225 42.647 T 06-07-2017 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 CAK77_RS15905 ce86b27028601351845d5c49877f7966 277 SUPERFAMILY SSF52313 6 235 2.75E-96 T 06-07-2017 IPR023591 Ribosomal protein S2, flavodoxin-like domain CAK77_RS15905 ce86b27028601351845d5c49877f7966 277 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 6 17 - T 06-07-2017 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 CAK77_RS15905 ce86b27028601351845d5c49877f7966 277 Gene3D G3DSA:3.40.50.10490 158 239 6.0E-68 T 06-07-2017 CAK77_RS15905 ce86b27028601351845d5c49877f7966 277 Gene3D G3DSA:3.40.50.10490 23 99 6.0E-68 T 06-07-2017 CAK77_RS15905 ce86b27028601351845d5c49877f7966 277 Gene3D G3DSA:1.10.287.610 100 152 2.0E-24 T 06-07-2017 CAK77_RS15905 ce86b27028601351845d5c49877f7966 277 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 3 226 8.5E-111 T 06-07-2017 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 CAK77_RS06540 47d12aa225bdaf48966d983f4a680ae1 268 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 142 161 6.0E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06540 47d12aa225bdaf48966d983f4a680ae1 268 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 69 80 6.0E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06540 47d12aa225bdaf48966d983f4a680ae1 268 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 122 130 6.0E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06540 47d12aa225bdaf48966d983f4a680ae1 268 SUPERFAMILY SSF51735 6 259 2.51E-57 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS06540 47d12aa225bdaf48966d983f4a680ae1 268 Gene3D G3DSA:3.40.50.720 6 258 1.3E-61 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS06540 47d12aa225bdaf48966d983f4a680ae1 268 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 129 157 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK77_RS06540 47d12aa225bdaf48966d983f4a680ae1 268 Pfam PF00106 short chain dehydrogenase 6 183 1.8E-43 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06540 47d12aa225bdaf48966d983f4a680ae1 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 69 80 2.0E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06540 47d12aa225bdaf48966d983f4a680ae1 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 116 132 2.0E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06540 47d12aa225bdaf48966d983f4a680ae1 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 142 161 2.0E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06540 47d12aa225bdaf48966d983f4a680ae1 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 2.0E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06540 47d12aa225bdaf48966d983f4a680ae1 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 180 2.0E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06675 c31983181058ac2713ad9fbe19df6a55 321 SUPERFAMILY SSF51730 42 316 2.51E-72 T 06-07-2017 IPR029041 FAD-linked oxidoreductase-like CAK77_RS06675 c31983181058ac2713ad9fbe19df6a55 321 Pfam PF01619 Proline dehydrogenase 59 312 5.8E-32 T 06-07-2017 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922 CAK77_RS06675 c31983181058ac2713ad9fbe19df6a55 321 PIRSF PIRSF000196 7 320 4.7E-105 T 06-07-2017 IPR008219 Proline dehydrogenase GO:0004657|GO:0010133 KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922 CAK77_RS06675 c31983181058ac2713ad9fbe19df6a55 321 Gene3D G3DSA:3.20.20.220 42 315 1.9E-68 T 06-07-2017 IPR029041 FAD-linked oxidoreductase-like CAK77_RS16605 7c72b421cc8279e5fba66cbb601410ab 378 SUPERFAMILY SSF47384 127 199 5.89E-11 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK77_RS16605 7c72b421cc8279e5fba66cbb601410ab 378 SUPERFAMILY SSF55874 199 366 3.01E-44 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS16605 7c72b421cc8279e5fba66cbb601410ab 378 PRINTS PR00344 Bacterial sensor protein C-terminal signature 325 343 1.9E-17 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK77_RS16605 7c72b421cc8279e5fba66cbb601410ab 378 PRINTS PR00344 Bacterial sensor protein C-terminal signature 350 363 1.9E-17 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK77_RS16605 7c72b421cc8279e5fba66cbb601410ab 378 PRINTS PR00344 Bacterial sensor protein C-terminal signature 290 304 1.9E-17 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK77_RS16605 7c72b421cc8279e5fba66cbb601410ab 378 PRINTS PR00344 Bacterial sensor protein C-terminal signature 308 318 1.9E-17 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK77_RS16605 7c72b421cc8279e5fba66cbb601410ab 378 SUPERFAMILY SSF158472 93 137 8.5E-6 T 06-07-2017 CAK77_RS16605 7c72b421cc8279e5fba66cbb601410ab 378 Gene3D G3DSA:3.30.565.10 210 370 8.5E-45 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS16605 7c72b421cc8279e5fba66cbb601410ab 378 SMART SM00388 143 207 3.2E-7 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK77_RS16605 7c72b421cc8279e5fba66cbb601410ab 378 Gene3D G3DSA:1.10.287.130 133 194 1.5E-10 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK77_RS16605 7c72b421cc8279e5fba66cbb601410ab 378 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 254 364 7.2E-25 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS16605 7c72b421cc8279e5fba66cbb601410ab 378 Pfam PF00672 HAMP domain 70 137 5.2E-13 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAK77_RS16605 7c72b421cc8279e5fba66cbb601410ab 378 Pfam PF00512 His Kinase A (phospho-acceptor) domain 143 194 5.2E-9 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK77_RS16605 7c72b421cc8279e5fba66cbb601410ab 378 SMART SM00304 89 142 4.1E-9 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAK77_RS16605 7c72b421cc8279e5fba66cbb601410ab 378 SMART SM00387 253 366 1.8E-41 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS18735 16d332cfee1c46f1850c2b18c0bd53f4 1311 SUPERFAMILY SSF52540 424 691 2.32E-26 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS18735 16d332cfee1c46f1850c2b18c0bd53f4 1311 SUPERFAMILY SSF52540 1068 1212 4.67E-10 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS18735 16d332cfee1c46f1850c2b18c0bd53f4 1311 Gene3D G3DSA:3.40.50.300 429 658 5.2E-18 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS18735 16d332cfee1c46f1850c2b18c0bd53f4 1311 Gene3D G3DSA:3.40.50.300 803 994 2.2E-10 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS18735 16d332cfee1c46f1850c2b18c0bd53f4 1311 Gene3D G3DSA:3.40.50.300 1082 1155 3.8E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS18735 16d332cfee1c46f1850c2b18c0bd53f4 1311 SMART SM00382 465 644 2.8 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS18735 16d332cfee1c46f1850c2b18c0bd53f4 1311 SMART SM00382 1102 1273 2.3 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS18735 16d332cfee1c46f1850c2b18c0bd53f4 1311 SMART SM00382 812 990 2.3 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS18735 16d332cfee1c46f1850c2b18c0bd53f4 1311 Pfam PF01580 FtsK/SpoIIIE family 435 562 1.5E-24 T 06-07-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CAK77_RS18735 16d332cfee1c46f1850c2b18c0bd53f4 1311 Pfam PF01580 FtsK/SpoIIIE family 1076 1152 3.5E-7 T 06-07-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CAK77_RS18735 16d332cfee1c46f1850c2b18c0bd53f4 1311 Pfam PF01580 FtsK/SpoIIIE family 791 1026 3.4E-58 T 06-07-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CAK77_RS18735 16d332cfee1c46f1850c2b18c0bd53f4 1311 TIGRFAM TIGR03925 T7SS_EccC_b: type VII secretion protein EccCb 740 1306 5.8E-252 T 06-07-2017 IPR023837 EccCb-like, Actinobacteria CAK77_RS18735 16d332cfee1c46f1850c2b18c0bd53f4 1311 TIGRFAM TIGR03924 T7SS_EccC_a: type VII secretion protein EccCa 8 688 1.3E-298 T 06-07-2017 IPR023836 EccCa-like, Actinobacteria CAK77_RS18735 16d332cfee1c46f1850c2b18c0bd53f4 1311 SUPERFAMILY SSF52540 759 1016 1.68E-21 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS07670 b26c26f7624f9131fe5f3c555a965daf 162 Pfam PF06210 Protein of unknown function (DUF1003) 40 140 7.4E-40 T 06-07-2017 IPR010406 Protein of unknown function DUF1003 CAK77_RS11380 d28deb38238ee04d4e8a1e55b256a5a5 293 TIGRFAM TIGR00761 argB: acetylglutamate kinase 29 266 7.7E-79 T 06-07-2017 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CAK77_RS11380 d28deb38238ee04d4e8a1e55b256a5a5 293 Hamap MF_00082_B Acetylglutamate kinase [argB]. 25 291 33.911 T 06-07-2017 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CAK77_RS11380 d28deb38238ee04d4e8a1e55b256a5a5 293 SUPERFAMILY SSF53633 6 291 1.24E-84 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase CAK77_RS11380 d28deb38238ee04d4e8a1e55b256a5a5 293 PRINTS PR00474 Glutamate 5-kinase family signature 190 217 5.2E-8 T 06-07-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 CAK77_RS11380 d28deb38238ee04d4e8a1e55b256a5a5 293 PRINTS PR00474 Glutamate 5-kinase family signature 58 72 5.2E-8 T 06-07-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 CAK77_RS11380 d28deb38238ee04d4e8a1e55b256a5a5 293 PRINTS PR00474 Glutamate 5-kinase family signature 241 261 5.2E-8 T 06-07-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 CAK77_RS11380 d28deb38238ee04d4e8a1e55b256a5a5 293 PIRSF PIRSF000728 5 291 9.5E-102 T 06-07-2017 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CAK77_RS11380 d28deb38238ee04d4e8a1e55b256a5a5 293 Pfam PF00696 Amino acid kinase family 28 268 5.7E-45 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase CAK77_RS11380 d28deb38238ee04d4e8a1e55b256a5a5 293 Gene3D G3DSA:3.40.1160.10 26 290 1.4E-97 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase CAK77_RS08915 7362b6206a0c32b5b3d6dfe5cb999f73 827 Gene3D G3DSA:3.40.50.2000 491 805 1.5E-133 T 06-07-2017 CAK77_RS08915 7362b6206a0c32b5b3d6dfe5cb999f73 827 Gene3D G3DSA:3.40.50.2000 16 490 2.5E-197 T 06-07-2017 CAK77_RS08915 7362b6206a0c32b5b3d6dfe5cb999f73 827 PIRSF PIRSF000460 3 827 9.6E-233 T 06-07-2017 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 CAK77_RS08915 7362b6206a0c32b5b3d6dfe5cb999f73 827 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 665 677 - T 06-07-2017 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 CAK77_RS08915 7362b6206a0c32b5b3d6dfe5cb999f73 827 TIGRFAM TIGR02093 P_ylase: glycogen/starch/alpha-glucan phosphorylases 19 820 0.0 T 06-07-2017 IPR011833 Glycogen/starch/alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 CAK77_RS08915 7362b6206a0c32b5b3d6dfe5cb999f73 827 SUPERFAMILY SSF53756 14 825 0.0 T 06-07-2017 CAK77_RS08915 7362b6206a0c32b5b3d6dfe5cb999f73 827 Pfam PF00343 Carbohydrate phosphorylase 108 820 0.0 T 06-07-2017 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 CAK77_RS08615 dbdf43ae79de992ad439617df66a3b76 256 PIRSF PIRSF006648 1 254 5.3E-24 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CAK77_RS08615 dbdf43ae79de992ad439617df66a3b76 256 Pfam PF01061 ABC-2 type transporter 10 220 4.5E-12 T 06-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CAK77_RS23325 77ed92aa630f975e70dedceccf91eb07 214 SUPERFAMILY SSF48498 96 213 6.97E-6 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS23325 77ed92aa630f975e70dedceccf91eb07 214 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 72 4.8E-12 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS23325 77ed92aa630f975e70dedceccf91eb07 214 SUPERFAMILY SSF46689 18 94 2.05E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS23325 77ed92aa630f975e70dedceccf91eb07 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 39 2.8E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS23325 77ed92aa630f975e70dedceccf91eb07 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 47 70 2.8E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS23325 77ed92aa630f975e70dedceccf91eb07 214 Gene3D G3DSA:1.10.357.10 20 213 1.7E-33 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS06485 d9dfca6a968e83b9279fa5aa9734717c 198 Gene3D G3DSA:3.40.50.150 22 154 1.5E-31 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS06485 d9dfca6a968e83b9279fa5aa9734717c 198 SUPERFAMILY SSF53335 9 174 9.36E-34 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS06485 d9dfca6a968e83b9279fa5aa9734717c 198 Pfam PF08241 Methyltransferase domain 29 121 4.3E-21 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CAK77_RS24165 80378859f1d1af669adcb423481da7ae 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 2.0E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS24165 80378859f1d1af669adcb423481da7ae 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 2.0E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS24165 80378859f1d1af669adcb423481da7ae 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 2.0E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS24165 80378859f1d1af669adcb423481da7ae 245 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK77_RS24165 80378859f1d1af669adcb423481da7ae 245 Gene3D G3DSA:3.40.50.720 2 244 1.4E-81 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS24165 80378859f1d1af669adcb423481da7ae 245 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 244 4.2E-55 T 06-07-2017 CAK77_RS24165 80378859f1d1af669adcb423481da7ae 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 3.8E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS24165 80378859f1d1af669adcb423481da7ae 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 3.8E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS24165 80378859f1d1af669adcb423481da7ae 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 3.8E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS24165 80378859f1d1af669adcb423481da7ae 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 3.8E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS24165 80378859f1d1af669adcb423481da7ae 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 3.8E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS24165 80378859f1d1af669adcb423481da7ae 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 3.8E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS24165 80378859f1d1af669adcb423481da7ae 245 SUPERFAMILY SSF51735 3 244 3.28E-77 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS06805 7b19c7a3b46cd721136ad9fcef7c12fe 301 Gene3D G3DSA:3.40.50.300 6 227 3.3E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS06805 7b19c7a3b46cd721136ad9fcef7c12fe 301 SMART SM00382 32 211 2.2E-8 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS06805 7b19c7a3b46cd721136ad9fcef7c12fe 301 SUPERFAMILY SSF52540 4 232 1.52E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS06805 7b19c7a3b46cd721136ad9fcef7c12fe 301 Pfam PF00005 ABC transporter 23 164 3.6E-24 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK77_RS06805 7b19c7a3b46cd721136ad9fcef7c12fe 301 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK77_RS09355 8109673116021b109046c61f941760f0 139 Pfam PF07681 DoxX 21 97 8.4E-10 T 06-07-2017 IPR032808 DoxX family CAK77_RS20850 b5ebb2c6c2b86f98e5096c9b3df55de3 500 Gene3D G3DSA:3.30.300.30 389 484 3.2E-16 T 06-07-2017 CAK77_RS20850 b5ebb2c6c2b86f98e5096c9b3df55de3 500 Gene3D G3DSA:2.30.38.10 318 382 5.4E-17 T 06-07-2017 CAK77_RS20850 b5ebb2c6c2b86f98e5096c9b3df55de3 500 Gene3D G3DSA:3.40.50.980 24 143 1.2E-17 T 06-07-2017 CAK77_RS20850 b5ebb2c6c2b86f98e5096c9b3df55de3 500 ProSitePatterns PS00455 Putative AMP-binding domain signature. 136 147 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK77_RS20850 b5ebb2c6c2b86f98e5096c9b3df55de3 500 Gene3D G3DSA:3.40.50.980 144 286 9.3E-26 T 06-07-2017 CAK77_RS20850 b5ebb2c6c2b86f98e5096c9b3df55de3 500 Pfam PF13193 AMP-binding enzyme C-terminal domain 399 472 2.7E-10 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAK77_RS20850 b5ebb2c6c2b86f98e5096c9b3df55de3 500 Pfam PF00501 AMP-binding enzyme 25 388 4.7E-57 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK77_RS20850 b5ebb2c6c2b86f98e5096c9b3df55de3 500 SUPERFAMILY SSF56801 24 491 5.36E-97 T 06-07-2017 CAK77_RS20430 b9eec56862e563be7353db0d2afa5771 218 SUPERFAMILY SSF51569 2 215 1.36E-66 T 06-07-2017 CAK77_RS20430 b9eec56862e563be7353db0d2afa5771 218 Hamap MF_00114 Deoxyribose-phosphate aldolase [deoC]. 1 217 29.91 T 06-07-2017 IPR028581 Deoxyribose-phosphate aldolase type I GO:0004139 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180 CAK77_RS20430 b9eec56862e563be7353db0d2afa5771 218 SMART SM01133 1 215 6.4E-75 T 06-07-2017 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-71336 CAK77_RS20430 b9eec56862e563be7353db0d2afa5771 218 Pfam PF01791 DeoC/LacD family aldolase 6 213 1.9E-21 T 06-07-2017 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-71336 CAK77_RS20430 b9eec56862e563be7353db0d2afa5771 218 PIRSF PIRSF001357 1 216 2.8E-65 T 06-07-2017 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-71336 CAK77_RS20430 b9eec56862e563be7353db0d2afa5771 218 Gene3D G3DSA:3.20.20.70 1 216 6.5E-82 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK77_RS20430 b9eec56862e563be7353db0d2afa5771 218 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 2 210 1.8E-62 T 06-07-2017 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-71336 CAK77_RS15980 570ff407056d992ace399c30e719c4d7 378 Gene3D G3DSA:3.40.50.450 136 301 2.0E-10 T 06-07-2017 CAK77_RS15980 570ff407056d992ace399c30e719c4d7 378 Gene3D G3DSA:1.10.10.10 315 362 3.9E-5 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS15980 570ff407056d992ace399c30e719c4d7 378 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 65 294 3.6E-67 T 06-07-2017 IPR003488 DNA recombination-mediator protein A GO:0009294 CAK77_RS15980 570ff407056d992ace399c30e719c4d7 378 Pfam PF02481 DNA recombination-mediator protein A 70 286 2.4E-64 T 06-07-2017 IPR003488 DNA recombination-mediator protein A GO:0009294 CAK77_RS15980 570ff407056d992ace399c30e719c4d7 378 SUPERFAMILY SSF102405 101 271 1.53E-26 T 06-07-2017 CAK77_RS24195 61d049f89f8f111add9581aa68223af3 157 SMART SM00344 4 110 5.5E-16 T 06-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CAK77_RS24195 61d049f89f8f111add9581aa68223af3 157 SUPERFAMILY SSF54909 64 148 1.26E-16 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAK77_RS24195 61d049f89f8f111add9581aa68223af3 157 Gene3D G3DSA:3.30.70.920 58 142 2.0E-17 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CAK77_RS24195 61d049f89f8f111add9581aa68223af3 157 Pfam PF13404 AsnC-type helix-turn-helix domain 4 43 2.3E-11 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAK77_RS24195 61d049f89f8f111add9581aa68223af3 157 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 4 20 1.6E-6 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAK77_RS24195 61d049f89f8f111add9581aa68223af3 157 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 20 31 1.6E-6 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAK77_RS24195 61d049f89f8f111add9581aa68223af3 157 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 31 50 1.6E-6 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAK77_RS24195 61d049f89f8f111add9581aa68223af3 157 Pfam PF01037 Lrp/AsnC ligand binding domain 73 139 3.3E-15 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CAK77_RS24195 61d049f89f8f111add9581aa68223af3 157 SUPERFAMILY SSF46785 3 64 7.0E-8 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS24195 61d049f89f8f111add9581aa68223af3 157 Gene3D G3DSA:1.10.10.10 1 43 2.4E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS18215 7ae3153caab696b3a2fbafca6876688b 158 Gene3D G3DSA:3.10.490.10 3 151 2.4E-49 T 06-07-2017 IPR013024 Butirosin biosynthesis, BtrG-like CAK77_RS18215 7ae3153caab696b3a2fbafca6876688b 158 Pfam PF13772 AIG2-like family 59 145 6.1E-25 T 06-07-2017 CAK77_RS18215 7ae3153caab696b3a2fbafca6876688b 158 SUPERFAMILY SSF110857 3 125 1.7E-15 T 06-07-2017 IPR013024 Butirosin biosynthesis, BtrG-like CAK77_RS15425 c498496441140b0b8009f425dcc02230 171 Gene3D G3DSA:3.30.70.920 77 165 2.1E-25 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CAK77_RS15425 c498496441140b0b8009f425dcc02230 171 Pfam PF13404 AsnC-type helix-turn-helix domain 24 65 4.3E-16 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAK77_RS15425 c498496441140b0b8009f425dcc02230 171 SUPERFAMILY SSF46785 23 83 1.78E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS15425 c498496441140b0b8009f425dcc02230 171 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 24 40 6.2E-15 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAK77_RS15425 c498496441140b0b8009f425dcc02230 171 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 51 70 6.2E-15 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAK77_RS15425 c498496441140b0b8009f425dcc02230 171 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 40 51 6.2E-15 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAK77_RS15425 c498496441140b0b8009f425dcc02230 171 Pfam PF01037 Lrp/AsnC ligand binding domain 91 163 1.8E-19 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CAK77_RS15425 c498496441140b0b8009f425dcc02230 171 SUPERFAMILY SSF54909 86 165 1.47E-16 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAK77_RS15425 c498496441140b0b8009f425dcc02230 171 SMART SM00344 24 133 7.9E-43 T 06-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CAK77_RS15425 c498496441140b0b8009f425dcc02230 171 Gene3D G3DSA:1.10.10.10 22 73 9.8E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS11285 4540afc1550f5de5dd565decb71fb6cc 1110 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 264 563 1.7E-97 T 06-07-2017 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal CAK77_RS11285 4540afc1550f5de5dd565decb71fb6cc 1110 SUPERFAMILY SSF55681 765 1107 1.65E-95 T 06-07-2017 CAK77_RS11285 4540afc1550f5de5dd565decb71fb6cc 1110 Pfam PF16995 Transmembrane region of lysyl-tRNA synthetase 37 246 6.6E-79 T 06-07-2017 IPR031553 Lysyl-tRNA synthetase, N-terminal transmembrane region KEGG: 00970+6.1.1.6 CAK77_RS11285 4540afc1550f5de5dd565decb71fb6cc 1110 PRINTS PR00982 Lysyl-tRNA synthetase signature 818 834 5.1E-31 T 06-07-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CAK77_RS11285 4540afc1550f5de5dd565decb71fb6cc 1110 PRINTS PR00982 Lysyl-tRNA synthetase signature 865 882 5.1E-31 T 06-07-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CAK77_RS11285 4540afc1550f5de5dd565decb71fb6cc 1110 PRINTS PR00982 Lysyl-tRNA synthetase signature 802 812 5.1E-31 T 06-07-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CAK77_RS11285 4540afc1550f5de5dd565decb71fb6cc 1110 PRINTS PR00982 Lysyl-tRNA synthetase signature 847 860 5.1E-31 T 06-07-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CAK77_RS11285 4540afc1550f5de5dd565decb71fb6cc 1110 PRINTS PR00982 Lysyl-tRNA synthetase signature 993 1009 5.1E-31 T 06-07-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CAK77_RS11285 4540afc1550f5de5dd565decb71fb6cc 1110 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 633 1109 9.9E-132 T 06-07-2017 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CAK77_RS11285 4540afc1550f5de5dd565decb71fb6cc 1110 Gene3D G3DSA:2.40.50.140 632 758 4.1E-27 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS11285 4540afc1550f5de5dd565decb71fb6cc 1110 Gene3D G3DSA:3.30.930.10 761 1105 2.7E-93 T 06-07-2017 CAK77_RS11285 4540afc1550f5de5dd565decb71fb6cc 1110 Pfam PF00152 tRNA synthetases class II (D, K and N) 767 1106 2.0E-64 T 06-07-2017 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK77_RS11285 4540afc1550f5de5dd565decb71fb6cc 1110 Pfam PF01336 OB-fold nucleic acid binding domain 675 749 1.8E-8 T 06-07-2017 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CAK77_RS11285 4540afc1550f5de5dd565decb71fb6cc 1110 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 637 1110 33.71 T 06-07-2017 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CAK77_RS11285 4540afc1550f5de5dd565decb71fb6cc 1110 SUPERFAMILY SSF50249 629 758 3.67E-28 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS15150 3ea5f05f8fcd5848d6a4e51d1c56784a 295 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 2 284 9.7E-69 T 06-07-2017 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CAK77_RS15150 3ea5f05f8fcd5848d6a4e51d1c56784a 295 SUPERFAMILY SSF54506 1 139 3.4E-31 T 06-07-2017 CAK77_RS15150 3ea5f05f8fcd5848d6a4e51d1c56784a 295 Gene3D G3DSA:3.10.310.10 1 136 1.6E-37 T 06-07-2017 CAK77_RS15150 3ea5f05f8fcd5848d6a4e51d1c56784a 295 SUPERFAMILY SSF54506 148 283 3.73E-25 T 06-07-2017 CAK77_RS15150 3ea5f05f8fcd5848d6a4e51d1c56784a 295 Gene3D G3DSA:3.10.310.10 137 269 2.0E-29 T 06-07-2017 CAK77_RS15150 3ea5f05f8fcd5848d6a4e51d1c56784a 295 Pfam PF01678 Diaminopimelate epimerase 3 140 4.0E-34 T 06-07-2017 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CAK77_RS15150 3ea5f05f8fcd5848d6a4e51d1c56784a 295 Pfam PF01678 Diaminopimelate epimerase 158 268 2.2E-19 T 06-07-2017 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CAK77_RS15150 3ea5f05f8fcd5848d6a4e51d1c56784a 295 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 78 92 - T 06-07-2017 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CAK77_RS15150 3ea5f05f8fcd5848d6a4e51d1c56784a 295 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 1 285 28.37 T 06-07-2017 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CAK77_RS13215 2af47696d9ca5e6b66acc8fc02275dbd 1183 SUPERFAMILY SSF89550 122 250 1.31E-27 T 06-07-2017 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CAK77_RS13215 2af47696d9ca5e6b66acc8fc02275dbd 1183 SUPERFAMILY SSF89550 8 94 1.31E-27 T 06-07-2017 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CAK77_RS13215 2af47696d9ca5e6b66acc8fc02275dbd 1183 SMART SM00481 9 76 9.8E-30 T 06-07-2017 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 CAK77_RS13215 2af47696d9ca5e6b66acc8fc02275dbd 1183 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 8 1060 0.0 T 06-07-2017 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAK77_RS13215 2af47696d9ca5e6b66acc8fc02275dbd 1183 Pfam PF14579 Helix-hairpin-helix motif 836 923 2.2E-23 T 06-07-2017 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAK77_RS13215 2af47696d9ca5e6b66acc8fc02275dbd 1183 Gene3D G3DSA:3.20.20.140 8 274 2.4E-39 T 06-07-2017 CAK77_RS13215 2af47696d9ca5e6b66acc8fc02275dbd 1183 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 318 763 7.2E-158 T 06-07-2017 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAK77_RS13215 2af47696d9ca5e6b66acc8fc02275dbd 1183 Pfam PF02811 PHP domain 10 196 4.6E-44 T 06-07-2017 IPR004013 PHP domain GO:0003824 CAK77_RS21300 670f3539a357b8c327a9ff70a0178813 455 Gene3D G3DSA:1.25.40.80 192 266 4.1E-32 T 06-07-2017 CAK77_RS21300 670f3539a357b8c327a9ff70a0178813 455 Gene3D G3DSA:3.40.50.620 3 155 4.8E-36 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS21300 670f3539a357b8c327a9ff70a0178813 455 Pfam PF03441 FAD binding domain of DNA photolyase 259 450 4.6E-77 T 06-07-2017 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 CAK77_RS21300 670f3539a357b8c327a9ff70a0178813 455 PRINTS PR00147 DNA photolyase signature 367 381 8.8E-25 T 06-07-2017 IPR002081 Cryptochrome/DNA photolyase class 1 CAK77_RS21300 670f3539a357b8c327a9ff70a0178813 455 PRINTS PR00147 DNA photolyase signature 133 149 8.8E-25 T 06-07-2017 IPR002081 Cryptochrome/DNA photolyase class 1 CAK77_RS21300 670f3539a357b8c327a9ff70a0178813 455 PRINTS PR00147 DNA photolyase signature 308 324 8.8E-25 T 06-07-2017 IPR002081 Cryptochrome/DNA photolyase class 1 CAK77_RS21300 670f3539a357b8c327a9ff70a0178813 455 PRINTS PR00147 DNA photolyase signature 328 346 8.8E-25 T 06-07-2017 IPR002081 Cryptochrome/DNA photolyase class 1 CAK77_RS21300 670f3539a357b8c327a9ff70a0178813 455 Gene3D G3DSA:1.10.579.10 267 451 8.1E-74 T 06-07-2017 CAK77_RS21300 670f3539a357b8c327a9ff70a0178813 455 SUPERFAMILY SSF48173 191 451 1.44E-95 T 06-07-2017 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 CAK77_RS21300 670f3539a357b8c327a9ff70a0178813 455 ProSitePatterns PS00394 DNA photolyases class 1 signature 1. 308 320 - T 06-07-2017 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal CAK77_RS21300 670f3539a357b8c327a9ff70a0178813 455 Pfam PF00875 DNA photolyase 3 155 2.1E-37 T 06-07-2017 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-1368108|Reactome: R-HSA-400253 CAK77_RS21300 670f3539a357b8c327a9ff70a0178813 455 SUPERFAMILY SSF52425 3 173 6.41E-42 T 06-07-2017 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-1368108|Reactome: R-HSA-400253 CAK77_RS17025 8b0ae0e6cfba1aa6c19afd6f04e23b4a 436 Pfam PF07690 Major Facilitator Superfamily 42 392 7.2E-26 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK77_RS17025 8b0ae0e6cfba1aa6c19afd6f04e23b4a 436 Gene3D G3DSA:1.20.1250.20 19 229 1.2E-17 T 06-07-2017 CAK77_RS17025 8b0ae0e6cfba1aa6c19afd6f04e23b4a 436 Gene3D G3DSA:1.20.1250.20 248 429 2.0E-20 T 06-07-2017 CAK77_RS17025 8b0ae0e6cfba1aa6c19afd6f04e23b4a 436 ProSitePatterns PS00217 Sugar transport proteins signature 2. 132 157 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CAK77_RS17025 8b0ae0e6cfba1aa6c19afd6f04e23b4a 436 SUPERFAMILY SSF103473 13 428 1.27E-58 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK77_RS17025 8b0ae0e6cfba1aa6c19afd6f04e23b4a 436 ProSitePatterns PS00216 Sugar transport proteins signature 1. 304 320 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CAK77_RS24315 8807244a3b8e64ab4c07313dc4c3283a 395 Gene3D G3DSA:1.10.101.10 5 86 3.1E-19 T 06-07-2017 IPR002477 Peptidoglycan binding-like CAK77_RS24315 8807244a3b8e64ab4c07313dc4c3283a 395 Gene3D G3DSA:1.10.101.10 99 155 2.0E-18 T 06-07-2017 IPR002477 Peptidoglycan binding-like CAK77_RS24315 8807244a3b8e64ab4c07313dc4c3283a 395 SUPERFAMILY SSF47090 7 79 4.97E-13 T 06-07-2017 IPR002477 Peptidoglycan binding-like CAK77_RS24315 8807244a3b8e64ab4c07313dc4c3283a 395 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 189 366 1.4E-26 T 06-07-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CAK77_RS24315 8807244a3b8e64ab4c07313dc4c3283a 395 SMART SM00646 251 366 4.2E-28 T 06-07-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CAK77_RS24315 8807244a3b8e64ab4c07313dc4c3283a 395 Pfam PF01471 Putative peptidoglycan binding domain 101 154 3.7E-15 T 06-07-2017 IPR002477 Peptidoglycan binding-like CAK77_RS24315 8807244a3b8e64ab4c07313dc4c3283a 395 Pfam PF01471 Putative peptidoglycan binding domain 13 79 6.4E-12 T 06-07-2017 IPR002477 Peptidoglycan binding-like CAK77_RS24315 8807244a3b8e64ab4c07313dc4c3283a 395 SUPERFAMILY SSF53187 186 369 2.42E-33 T 06-07-2017 CAK77_RS24315 8807244a3b8e64ab4c07313dc4c3283a 395 SUPERFAMILY SSF47090 95 156 9.68E-17 T 06-07-2017 IPR002477 Peptidoglycan binding-like CAK77_RS24315 8807244a3b8e64ab4c07313dc4c3283a 395 Gene3D G3DSA:3.40.630.40 186 369 1.9E-32 T 06-07-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CAK77_RS14865 7cc835dc1ebbce544b1c92282483ac94 400 SMART SM00341 227 307 1.1E-15 T 06-07-2017 IPR002121 HRDC domain GO:0003676|GO:0005622 CAK77_RS14865 7cc835dc1ebbce544b1c92282483ac94 400 SUPERFAMILY SSF53098 8 225 6.74E-52 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAK77_RS14865 7cc835dc1ebbce544b1c92282483ac94 400 SMART SM00474 21 188 2.8E-32 T 06-07-2017 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 CAK77_RS14865 7cc835dc1ebbce544b1c92282483ac94 400 Pfam PF01612 3'-5' exonuclease 28 187 8.3E-32 T 06-07-2017 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 CAK77_RS14865 7cc835dc1ebbce544b1c92282483ac94 400 Pfam PF00570 HRDC domain 230 297 1.7E-12 T 06-07-2017 IPR002121 HRDC domain GO:0003676|GO:0005622 CAK77_RS14865 7cc835dc1ebbce544b1c92282483ac94 400 Gene3D G3DSA:3.30.420.10 60 194 4.9E-6 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAK77_RS14865 7cc835dc1ebbce544b1c92282483ac94 400 SUPERFAMILY SSF47819 209 303 2.62E-20 T 06-07-2017 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 CAK77_RS02955 749c1ec92310497318a8af612b2316db 218 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 1 214 27.064 T 06-07-2017 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 CAK77_RS02955 749c1ec92310497318a8af612b2316db 218 Gene3D G3DSA:3.90.550.10 1 213 3.4E-67 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK77_RS02955 749c1ec92310497318a8af612b2316db 218 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 90 97 - T 06-07-2017 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 CAK77_RS02955 749c1ec92310497318a8af612b2316db 218 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 1 212 8.6E-71 T 06-07-2017 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 CAK77_RS02955 749c1ec92310497318a8af612b2316db 218 SUPERFAMILY SSF53448 1 211 1.71E-54 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK77_RS02955 749c1ec92310497318a8af612b2316db 218 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 1 211 4.0E-66 T 06-07-2017 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 CAK77_RS04570 a915af1f2df07d5a50e8f4075d4a87f3 539 SUPERFAMILY SSF51971 340 385 4.53E-51 T 06-07-2017 CAK77_RS04570 a915af1f2df07d5a50e8f4075d4a87f3 539 SUPERFAMILY SSF51971 86 292 4.53E-51 T 06-07-2017 CAK77_RS04570 a915af1f2df07d5a50e8f4075d4a87f3 539 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 26 37 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CAK77_RS04570 a915af1f2df07d5a50e8f4075d4a87f3 539 PRINTS PR00419 Adrenodoxin reductase family signature 87 109 5.0E-21 T 06-07-2017 CAK77_RS04570 a915af1f2df07d5a50e8f4075d4a87f3 539 PRINTS PR00419 Adrenodoxin reductase family signature 226 240 5.0E-21 T 06-07-2017 CAK77_RS04570 a915af1f2df07d5a50e8f4075d4a87f3 539 PRINTS PR00419 Adrenodoxin reductase family signature 111 124 5.0E-21 T 06-07-2017 CAK77_RS04570 a915af1f2df07d5a50e8f4075d4a87f3 539 PRINTS PR00419 Adrenodoxin reductase family signature 154 164 5.0E-21 T 06-07-2017 CAK77_RS04570 a915af1f2df07d5a50e8f4075d4a87f3 539 Gene3D G3DSA:3.50.50.60 177 384 1.2E-56 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS04570 a915af1f2df07d5a50e8f4075d4a87f3 539 PIRSF PIRSF000362 81 519 4.2E-137 T 06-07-2017 IPR021163 Ferredoxin-NADP+ reductase, adrenodoxin-type GO:0016491|GO:0055114 Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 CAK77_RS04570 a915af1f2df07d5a50e8f4075d4a87f3 539 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 87 243 2.4E-10 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS04570 a915af1f2df07d5a50e8f4075d4a87f3 539 Gene3D G3DSA:3.30.70.20 14 51 2.2E-9 T 06-07-2017 CAK77_RS04570 a915af1f2df07d5a50e8f4075d4a87f3 539 SUPERFAMILY SSF54862 2 67 1.03E-9 T 06-07-2017 CAK77_RS04570 a915af1f2df07d5a50e8f4075d4a87f3 539 Gene3D G3DSA:3.40.50.720 86 176 4.0E-74 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS04570 a915af1f2df07d5a50e8f4075d4a87f3 539 Gene3D G3DSA:3.40.50.720 385 516 4.0E-74 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS04570 a915af1f2df07d5a50e8f4075d4a87f3 539 Pfam PF00037 4Fe-4S binding domain 20 42 7.5E-8 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CAK77_RS18210 41e5d41f561c14807efab3b2c7e71c5c 471 Gene3D G3DSA:3.30.390.30 347 464 3.4E-29 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CAK77_RS18210 41e5d41f561c14807efab3b2c7e71c5c 471 Gene3D G3DSA:3.50.50.60 3 149 1.4E-31 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS18210 41e5d41f561c14807efab3b2c7e71c5c 471 SUPERFAMILY SSF51905 3 341 1.8E-50 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS18210 41e5d41f561c14807efab3b2c7e71c5c 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 413 428 1.3E-48 T 06-07-2017 CAK77_RS18210 41e5d41f561c14807efab3b2c7e71c5c 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 269 283 1.3E-48 T 06-07-2017 CAK77_RS18210 41e5d41f561c14807efab3b2c7e71c5c 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 348 369 1.3E-48 T 06-07-2017 CAK77_RS18210 41e5d41f561c14807efab3b2c7e71c5c 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 1.3E-48 T 06-07-2017 CAK77_RS18210 41e5d41f561c14807efab3b2c7e71c5c 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 39 54 1.3E-48 T 06-07-2017 CAK77_RS18210 41e5d41f561c14807efab3b2c7e71c5c 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 312 319 1.3E-48 T 06-07-2017 CAK77_RS18210 41e5d41f561c14807efab3b2c7e71c5c 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 435 455 1.3E-48 T 06-07-2017 CAK77_RS18210 41e5d41f561c14807efab3b2c7e71c5c 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 148 157 1.3E-48 T 06-07-2017 CAK77_RS18210 41e5d41f561c14807efab3b2c7e71c5c 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 184 209 1.3E-48 T 06-07-2017 CAK77_RS18210 41e5d41f561c14807efab3b2c7e71c5c 471 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 332 5.5E-56 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS18210 41e5d41f561c14807efab3b2c7e71c5c 471 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 268 284 1.0E-32 T 06-07-2017 CAK77_RS18210 41e5d41f561c14807efab3b2c7e71c5c 471 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 1.0E-32 T 06-07-2017 CAK77_RS18210 41e5d41f561c14807efab3b2c7e71c5c 471 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 297 319 1.0E-32 T 06-07-2017 CAK77_RS18210 41e5d41f561c14807efab3b2c7e71c5c 471 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 145 163 1.0E-32 T 06-07-2017 CAK77_RS18210 41e5d41f561c14807efab3b2c7e71c5c 471 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 184 202 1.0E-32 T 06-07-2017 CAK77_RS18210 41e5d41f561c14807efab3b2c7e71c5c 471 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 352 460 2.3E-22 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CAK77_RS18210 41e5d41f561c14807efab3b2c7e71c5c 471 PIRSF PIRSF000350 1 465 7.0E-77 T 06-07-2017 CAK77_RS18210 41e5d41f561c14807efab3b2c7e71c5c 471 Gene3D G3DSA:3.50.50.60 150 341 7.0E-49 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS18210 41e5d41f561c14807efab3b2c7e71c5c 471 SUPERFAMILY SSF55424 351 464 1.08E-25 T 06-07-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CAK77_RS06930 a73d585032fbb56b84fe4ce5e16896e9 387 PIRSF PIRSF000106 31 387 1.0E-67 T 06-07-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 CAK77_RS06930 a73d585032fbb56b84fe4ce5e16896e9 387 Gene3D G3DSA:3.40.50.720 162 381 1.1E-69 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS06930 a73d585032fbb56b84fe4ce5e16896e9 387 ProSitePatterns PS00331 Malic enzymes signature. 160 176 - T 06-07-2017 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 CAK77_RS06930 a73d585032fbb56b84fe4ce5e16896e9 387 SMART SM01274 19 152 1.8E-69 T 06-07-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CAK77_RS06930 a73d585032fbb56b84fe4ce5e16896e9 387 SUPERFAMILY SSF51735 164 386 2.17E-64 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS06930 a73d585032fbb56b84fe4ce5e16896e9 387 Pfam PF00390 Malic enzyme, N-terminal domain 21 150 1.4E-24 T 06-07-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CAK77_RS06930 a73d585032fbb56b84fe4ce5e16896e9 387 Pfam PF03949 Malic enzyme, NAD binding domain 166 364 5.1E-18 T 06-07-2017 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 CAK77_RS06930 a73d585032fbb56b84fe4ce5e16896e9 387 PRINTS PR00072 Malic enzyme signature 81 103 1.9E-7 T 06-07-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 CAK77_RS06930 a73d585032fbb56b84fe4ce5e16896e9 387 PRINTS PR00072 Malic enzyme signature 160 176 1.9E-7 T 06-07-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 CAK77_RS06930 a73d585032fbb56b84fe4ce5e16896e9 387 PRINTS PR00072 Malic enzyme signature 191 207 1.9E-7 T 06-07-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 CAK77_RS06930 a73d585032fbb56b84fe4ce5e16896e9 387 SMART SM00919 164 384 1.4E-102 T 06-07-2017 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 CAK77_RS06930 a73d585032fbb56b84fe4ce5e16896e9 387 SUPERFAMILY SSF53223 13 162 2.3E-50 T 06-07-2017 CAK77_RS06930 a73d585032fbb56b84fe4ce5e16896e9 387 Gene3D G3DSA:3.40.50.10380 16 161 1.6E-49 T 06-07-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CAK77_RS22330 4f9e92a74fb167a9fbe2cf2cb2ebc63a 485 Pfam PF00171 Aldehyde dehydrogenase family 13 474 1.8E-166 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAK77_RS22330 4f9e92a74fb167a9fbe2cf2cb2ebc63a 485 Gene3D G3DSA:3.40.309.10 265 440 1.0E-65 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAK77_RS22330 4f9e92a74fb167a9fbe2cf2cb2ebc63a 485 Gene3D G3DSA:3.40.605.10 6 264 8.6E-89 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAK77_RS22330 4f9e92a74fb167a9fbe2cf2cb2ebc63a 485 SUPERFAMILY SSF53720 4 477 6.81E-160 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAK77_RS22330 4f9e92a74fb167a9fbe2cf2cb2ebc63a 485 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 249 256 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CAK77_RS04510 39c0f13a95fd958f16ba624708d3de04 279 Gene3D G3DSA:3.40.50.720 8 219 5.9E-56 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS04510 39c0f13a95fd958f16ba624708d3de04 279 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 2.9E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS04510 39c0f13a95fd958f16ba624708d3de04 279 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 2.9E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS04510 39c0f13a95fd958f16ba624708d3de04 279 SUPERFAMILY SSF51735 10 256 3.38E-55 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS04510 39c0f13a95fd958f16ba624708d3de04 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 1.2E-18 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS04510 39c0f13a95fd958f16ba624708d3de04 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 1.2E-18 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS04510 39c0f13a95fd958f16ba624708d3de04 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 1.2E-18 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS04510 39c0f13a95fd958f16ba624708d3de04 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 1.2E-18 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS04510 39c0f13a95fd958f16ba624708d3de04 279 Pfam PF00106 short chain dehydrogenase 11 197 1.8E-46 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS13605 0f8d3a76828bd636235bfd1104dcb313 301 Pfam PF03668 P-loop ATPase protein family 17 301 6.7E-121 T 06-07-2017 IPR005337 RapZ-like family GO:0005524 CAK77_RS13605 0f8d3a76828bd636235bfd1104dcb313 301 Gene3D G3DSA:3.40.50.300 13 172 1.2E-17 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS13605 0f8d3a76828bd636235bfd1104dcb313 301 SUPERFAMILY SSF52540 19 171 2.2E-12 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS13605 0f8d3a76828bd636235bfd1104dcb313 301 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 17 300 40.068 T 06-07-2017 IPR005337 RapZ-like family GO:0005524 CAK77_RS13605 0f8d3a76828bd636235bfd1104dcb313 301 PIRSF PIRSF005052 17 301 1.0E-110 T 06-07-2017 IPR005337 RapZ-like family GO:0005524 CAK77_RS22340 561f388391f81ef5514bebb5c81fb7da 303 TIGRFAM TIGR01692 HIBADH: 3-hydroxyisobutyrate dehydrogenase 6 291 1.1E-89 T 06-07-2017 IPR011548 3-hydroxyisobutyrate dehydrogenase GO:0008442|GO:0051287|GO:0055114 KEGG: 00280+1.1.1.31|Reactome: R-HSA-70895 CAK77_RS22340 561f388391f81ef5514bebb5c81fb7da 303 SUPERFAMILY SSF51735 4 163 6.34E-39 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS22340 561f388391f81ef5514bebb5c81fb7da 303 Gene3D G3DSA:1.10.1040.10 165 292 1.6E-35 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAK77_RS22340 561f388391f81ef5514bebb5c81fb7da 303 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 4 162 1.1E-43 T 06-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CAK77_RS22340 561f388391f81ef5514bebb5c81fb7da 303 Gene3D G3DSA:3.40.50.720 3 163 5.1E-51 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS22340 561f388391f81ef5514bebb5c81fb7da 303 SUPERFAMILY SSF48179 164 291 1.59E-36 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAK77_RS22340 561f388391f81ef5514bebb5c81fb7da 303 PIRSF PIRSF000103 1 299 3.9E-73 T 06-07-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CAK77_RS22340 561f388391f81ef5514bebb5c81fb7da 303 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 165 291 1.1E-28 T 06-07-2017 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 CAK77_RS06830 9532fb346ebd81d726f3306a5247092f 492 Gene3D G3DSA:2.40.10.10 189 283 2.5E-29 T 06-07-2017 CAK77_RS06830 9532fb346ebd81d726f3306a5247092f 492 Pfam PF13180 PDZ domain 405 486 1.0E-13 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAK77_RS06830 9532fb346ebd81d726f3306a5247092f 492 Gene3D G3DSA:2.40.10.10 287 406 3.8E-40 T 06-07-2017 CAK77_RS06830 9532fb346ebd81d726f3306a5247092f 492 SUPERFAMILY SSF50156 385 487 1.97E-19 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAK77_RS06830 9532fb346ebd81d726f3306a5247092f 492 SUPERFAMILY SSF50494 193 400 1.65E-56 T 06-07-2017 IPR009003 Peptidase S1, PA clan CAK77_RS06830 9532fb346ebd81d726f3306a5247092f 492 Pfam PF13365 Trypsin-like peptidase domain 218 365 3.1E-34 T 06-07-2017 CAK77_RS06830 9532fb346ebd81d726f3306a5247092f 492 PRINTS PR00834 HtrA/DegQ protease family signature 254 274 1.3E-43 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAK77_RS06830 9532fb346ebd81d726f3306a5247092f 492 PRINTS PR00834 HtrA/DegQ protease family signature 436 448 1.3E-43 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAK77_RS06830 9532fb346ebd81d726f3306a5247092f 492 PRINTS PR00834 HtrA/DegQ protease family signature 295 319 1.3E-43 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAK77_RS06830 9532fb346ebd81d726f3306a5247092f 492 PRINTS PR00834 HtrA/DegQ protease family signature 336 353 1.3E-43 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAK77_RS06830 9532fb346ebd81d726f3306a5247092f 492 PRINTS PR00834 HtrA/DegQ protease family signature 227 239 1.3E-43 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAK77_RS06830 9532fb346ebd81d726f3306a5247092f 492 PRINTS PR00834 HtrA/DegQ protease family signature 358 375 1.3E-43 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAK77_RS06830 9532fb346ebd81d726f3306a5247092f 492 SMART SM00228 404 478 3.3E-10 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAK77_RS06830 9532fb346ebd81d726f3306a5247092f 492 Gene3D G3DSA:2.30.42.10 407 489 2.4E-18 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAK77_RS18365 22846a23e4502d95c35ee0c99172616a 453 Gene3D G3DSA:3.90.1150.10 305 441 3.9E-45 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK77_RS18365 22846a23e4502d95c35ee0c99172616a 453 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 24 438 1.2E-137 T 06-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CAK77_RS18365 22846a23e4502d95c35ee0c99172616a 453 SUPERFAMILY SSF53383 22 437 1.3E-118 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK77_RS18365 22846a23e4502d95c35ee0c99172616a 453 PIRSF PIRSF001434 9 442 1.6E-127 T 06-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CAK77_RS18365 22846a23e4502d95c35ee0c99172616a 453 TIGRFAM TIGR01326 OAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 23 438 5.0E-201 T 06-07-2017 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 KEGG: 00270+2.5.1.49|MetaCyc: PWY-5344|MetaCyc: PWY-7174 CAK77_RS18365 22846a23e4502d95c35ee0c99172616a 453 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 217 231 - T 06-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CAK77_RS18365 22846a23e4502d95c35ee0c99172616a 453 Gene3D G3DSA:3.40.640.10 22 303 1.4E-116 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK77_RS10115 5e1b477b447f8416eb302f03f4729a94 368 SMART SM00829 10 366 3.3E-5 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAK77_RS10115 5e1b477b447f8416eb302f03f4729a94 368 SUPERFAMILY SSF51735 157 332 1.84E-31 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS10115 5e1b477b447f8416eb302f03f4729a94 368 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 153 6.0E-28 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAK77_RS10115 5e1b477b447f8416eb302f03f4729a94 368 SUPERFAMILY SSF50129 1 190 8.67E-62 T 06-07-2017 IPR011032 GroES-like CAK77_RS10115 5e1b477b447f8416eb302f03f4729a94 368 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 60 74 - T 06-07-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CAK77_RS10115 5e1b477b447f8416eb302f03f4729a94 368 Gene3D G3DSA:3.90.180.10 1 187 1.3E-61 T 06-07-2017 IPR011032 GroES-like CAK77_RS10115 5e1b477b447f8416eb302f03f4729a94 368 TIGRFAM TIGR03989 Rxyl_3153: NDMA-dependent alcohol dehydrogenase, Rxyl_3153 family 2 368 1.4E-172 T 06-07-2017 IPR023921 Alcohol dehydrogenase, zinc-type, actinomycetes KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396 CAK77_RS10115 5e1b477b447f8416eb302f03f4729a94 368 Pfam PF00107 Zinc-binding dehydrogenase 195 324 4.1E-15 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAK77_RS10115 5e1b477b447f8416eb302f03f4729a94 368 SUPERFAMILY SSF50129 319 368 4.24E-10 T 06-07-2017 IPR011032 GroES-like CAK77_RS10115 5e1b477b447f8416eb302f03f4729a94 368 Gene3D G3DSA:3.40.50.720 188 310 9.0E-24 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS20830 f86f80eeba9c6763557bb20d43505d20 301 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 141 157 3.9E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS20830 f86f80eeba9c6763557bb20d43505d20 301 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 186 3.9E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS20830 f86f80eeba9c6763557bb20d43505d20 301 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 3.9E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS20830 f86f80eeba9c6763557bb20d43505d20 301 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 3.9E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS20830 f86f80eeba9c6763557bb20d43505d20 301 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 188 205 3.9E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS20830 f86f80eeba9c6763557bb20d43505d20 301 SUPERFAMILY SSF51735 7 252 8.8E-56 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS20830 f86f80eeba9c6763557bb20d43505d20 301 Gene3D G3DSA:3.40.50.720 7 251 8.9E-60 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS20830 f86f80eeba9c6763557bb20d43505d20 301 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 12 224 0.0041 T 06-07-2017 CAK77_RS20830 f86f80eeba9c6763557bb20d43505d20 301 Pfam PF00106 short chain dehydrogenase 13 204 1.8E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS20830 f86f80eeba9c6763557bb20d43505d20 301 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 87 98 9.5E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS20830 f86f80eeba9c6763557bb20d43505d20 301 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 167 186 9.5E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS20830 f86f80eeba9c6763557bb20d43505d20 301 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 147 155 9.5E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS20830 f86f80eeba9c6763557bb20d43505d20 301 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 154 182 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK77_RS04035 0f393697a612ca419f41f21852f9cc0c 761 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 633 716 6.9E-17 T 06-07-2017 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain CAK77_RS04035 0f393697a612ca419f41f21852f9cc0c 761 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 325 489 2.6E-59 T 06-07-2017 IPR004474 Cell envelope-related transcriptional attenuator domain CAK77_RS04035 0f393697a612ca419f41f21852f9cc0c 761 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 325 488 3.3E-48 T 06-07-2017 IPR004474 Cell envelope-related transcriptional attenuator domain CAK77_RS07285 b4598666457eeeb8e0602a12a2c84c0c 308 Gene3D G3DSA:1.10.287.80 20 61 1.8E-26 T 06-07-2017 CAK77_RS07285 b4598666457eeeb8e0602a12a2c84c0c 308 Gene3D G3DSA:1.10.287.80 217 250 1.8E-26 T 06-07-2017 CAK77_RS07285 b4598666457eeeb8e0602a12a2c84c0c 308 Gene3D G3DSA:3.40.1380.10 64 207 3.8E-42 T 06-07-2017 CAK77_RS07285 b4598666457eeeb8e0602a12a2c84c0c 308 PRINTS PR00126 ATP synthase gamma subunit signature 249 268 2.3E-32 T 06-07-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 CAK77_RS07285 b4598666457eeeb8e0602a12a2c84c0c 308 PRINTS PR00126 ATP synthase gamma subunit signature 181 198 2.3E-32 T 06-07-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 CAK77_RS07285 b4598666457eeeb8e0602a12a2c84c0c 308 PRINTS PR00126 ATP synthase gamma subunit signature 74 93 2.3E-32 T 06-07-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 CAK77_RS07285 b4598666457eeeb8e0602a12a2c84c0c 308 PRINTS PR00126 ATP synthase gamma subunit signature 280 301 2.3E-32 T 06-07-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 CAK77_RS07285 b4598666457eeeb8e0602a12a2c84c0c 308 Hamap MF_00815 ATP synthase gamma chain [atpG]. 2 302 33.976 T 06-07-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 CAK77_RS07285 b4598666457eeeb8e0602a12a2c84c0c 308 Gene3D G3DSA:1.10.287.80 251 297 5.3E-26 T 06-07-2017 CAK77_RS07285 b4598666457eeeb8e0602a12a2c84c0c 308 SUPERFAMILY SSF52943 3 302 1.83E-78 T 06-07-2017 IPR023633 ATPase, F1 complex, gamma subunit domain Reactome: R-HSA-163210 CAK77_RS07285 b4598666457eeeb8e0602a12a2c84c0c 308 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 3 302 8.9E-103 T 06-07-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 CAK77_RS07285 b4598666457eeeb8e0602a12a2c84c0c 308 Pfam PF00231 ATP synthase 5 302 1.2E-85 T 06-07-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 CAK77_RS12040 d69d6311cfa7885086e89ee25b87227b 493 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 172 197 6.8E-8 T 06-07-2017 CAK77_RS12040 d69d6311cfa7885086e89ee25b87227b 493 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 131 140 6.8E-8 T 06-07-2017 CAK77_RS12040 d69d6311cfa7885086e89ee25b87227b 493 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 6.8E-8 T 06-07-2017 CAK77_RS12040 d69d6311cfa7885086e89ee25b87227b 493 Gene3D G3DSA:3.50.50.60 301 341 8.3E-7 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS12040 d69d6311cfa7885086e89ee25b87227b 493 Gene3D G3DSA:3.50.50.60 176 219 8.3E-7 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS12040 d69d6311cfa7885086e89ee25b87227b 493 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 8 239 2.3E-17 T 06-07-2017 CAK77_RS12040 d69d6311cfa7885086e89ee25b87227b 493 SUPERFAMILY SSF51905 281 452 7.59E-14 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS12040 d69d6311cfa7885086e89ee25b87227b 493 SUPERFAMILY SSF51905 1 224 5.48E-52 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS12040 d69d6311cfa7885086e89ee25b87227b 493 Gene3D G3DSA:3.50.50.60 2 175 4.7E-69 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS12040 d69d6311cfa7885086e89ee25b87227b 493 Gene3D G3DSA:3.50.50.60 383 469 4.7E-69 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS02980 a9095cbc3818e03aebfbc857b62370ca 238 SUPERFAMILY SSF88713 3 237 2.82E-88 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CAK77_RS02980 a9095cbc3818e03aebfbc857b62370ca 238 Pfam PF03746 LamB/YcsF family 4 227 1.9E-88 T 06-07-2017 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF CAK77_RS24295 0d1c9e2011c452bd48942c7222f3c162 194 Gene3D G3DSA:1.10.1740.10 9 115 1.8E-32 T 06-07-2017 CAK77_RS24295 0d1c9e2011c452bd48942c7222f3c162 194 SUPERFAMILY SSF88946 9 112 7.22E-29 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS24295 0d1c9e2011c452bd48942c7222f3c162 194 Pfam PF04542 Sigma-70 region 2 31 97 4.8E-17 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS24295 0d1c9e2011c452bd48942c7222f3c162 194 Gene3D G3DSA:1.10.10.10 123 178 8.0E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS24295 0d1c9e2011c452bd48942c7222f3c162 194 SUPERFAMILY SSF88659 119 176 5.01E-14 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS24295 0d1c9e2011c452bd48942c7222f3c162 194 Pfam PF08281 Sigma-70, region 4 124 174 9.6E-16 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS24295 0d1c9e2011c452bd48942c7222f3c162 194 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 26 178 4.8E-26 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS15390 7719ffcade18c52fe962283d45523e75 424 SUPERFAMILY SSF52777 174 419 7.67E-32 T 06-07-2017 CAK77_RS15390 7719ffcade18c52fe962283d45523e75 424 SUPERFAMILY SSF52777 28 169 1.22E-6 T 06-07-2017 CAK77_RS15390 7719ffcade18c52fe962283d45523e75 424 Pfam PF16911 Phthiocerol/phthiodiolone dimycocerosyl transferase C-terminus 298 412 1.5E-22 T 06-07-2017 IPR031641 Phthiocerol/phthiodiolone dimycocerosyl transferase, C-terminal CAK77_RS03495 7cd54500798869f466fd018f46293193 247 SUPERFAMILY SSF46894 146 244 3.68E-27 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAK77_RS03495 7cd54500798869f466fd018f46293193 247 Gene3D G3DSA:1.10.10.10 145 246 2.8E-33 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS03495 7cd54500798869f466fd018f46293193 247 SMART SM00862 169 243 2.4E-24 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAK77_RS03495 7cd54500798869f466fd018f46293193 247 Pfam PF00072 Response regulator receiver domain 23 132 3.3E-27 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK77_RS03495 7cd54500798869f466fd018f46293193 247 Pfam PF00486 Transcriptional regulatory protein, C terminal 169 243 1.8E-23 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAK77_RS03495 7cd54500798869f466fd018f46293193 247 Gene3D G3DSA:3.40.50.2300 19 143 8.3E-40 T 06-07-2017 CAK77_RS03495 7cd54500798869f466fd018f46293193 247 SUPERFAMILY SSF52172 18 145 4.84E-42 T 06-07-2017 IPR011006 CheY-like superfamily CAK77_RS03495 7cd54500798869f466fd018f46293193 247 SMART SM00448 21 132 2.8E-42 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK77_RS17415 92132d5e34877044e6e74d0769b64e65 350 SUPERFAMILY SSF82861 40 131 6.41E-6 T 06-07-2017 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 CAK77_RS17415 92132d5e34877044e6e74d0769b64e65 350 SUPERFAMILY SSF50182 133 198 7.85E-11 T 06-07-2017 IPR010920 LSM domain CAK77_RS17415 92132d5e34877044e6e74d0769b64e65 350 Pfam PF00924 Mechanosensitive ion channel 90 295 1.1E-37 T 06-07-2017 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 CAK77_RS17415 92132d5e34877044e6e74d0769b64e65 350 Gene3D G3DSA:2.30.30.60 148 198 1.0E-12 T 06-07-2017 CAK77_RS17415 92132d5e34877044e6e74d0769b64e65 350 SUPERFAMILY SSF82689 202 295 2.62E-7 T 06-07-2017 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 CAK77_RS00100 6208b9c73461623cab4fa29cfd93fd44 839 SMART SM00434 20 478 1.2E-272 T 06-07-2017 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAK77_RS00100 6208b9c73461623cab4fa29cfd93fd44 839 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 41 485 1.4E-145 T 06-07-2017 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAK77_RS00100 6208b9c73461623cab4fa29cfd93fd44 839 SUPERFAMILY SSF56719 13 502 1.96E-168 T 06-07-2017 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CAK77_RS00100 6208b9c73461623cab4fa29cfd93fd44 839 Gene3D G3DSA:1.10.268.10 377 476 6.6E-30 T 06-07-2017 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAK77_RS00100 6208b9c73461623cab4fa29cfd93fd44 839 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 17 819 0.0 T 06-07-2017 CAK77_RS00100 6208b9c73461623cab4fa29cfd93fd44 839 Gene3D G3DSA:2.120.10.90 509 818 7.1E-117 T 06-07-2017 CAK77_RS00100 6208b9c73461623cab4fa29cfd93fd44 839 SUPERFAMILY SSF101904 512 830 1.44E-100 T 06-07-2017 CAK77_RS00100 6208b9c73461623cab4fa29cfd93fd44 839 Gene3D G3DSA:3.90.199.10 33 290 3.7E-112 T 06-07-2017 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 CAK77_RS00100 6208b9c73461623cab4fa29cfd93fd44 839 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 567 610 2.9E-8 T 06-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CAK77_RS00100 6208b9c73461623cab4fa29cfd93fd44 839 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 517 564 1.5E-11 T 06-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CAK77_RS00100 6208b9c73461623cab4fa29cfd93fd44 839 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 724 771 2.5E-12 T 06-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CAK77_RS00100 6208b9c73461623cab4fa29cfd93fd44 839 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 624 668 7.1E-9 T 06-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CAK77_RS00100 6208b9c73461623cab4fa29cfd93fd44 839 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 775 817 1.1E-8 T 06-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CAK77_RS00100 6208b9c73461623cab4fa29cfd93fd44 839 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 671 719 6.3E-11 T 06-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CAK77_RS00100 6208b9c73461623cab4fa29cfd93fd44 839 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 14 822 23.615 T 06-07-2017 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CAK77_RS23815 9f90be01d942ae9216316829df577d14 342 SUPERFAMILY SSF54637 14 151 1.26E-24 T 06-07-2017 IPR029069 HotDog domain CAK77_RS23815 9f90be01d942ae9216316829df577d14 342 Gene3D G3DSA:3.10.129.10 12 146 8.1E-20 T 06-07-2017 IPR029069 HotDog domain CAK77_RS23815 9f90be01d942ae9216316829df577d14 342 SUPERFAMILY SSF54637 204 327 3.68E-22 T 06-07-2017 IPR029069 HotDog domain CAK77_RS23815 9f90be01d942ae9216316829df577d14 342 Pfam PF13452 N-terminal half of MaoC dehydratase 14 141 6.3E-27 T 06-07-2017 CAK77_RS23815 9f90be01d942ae9216316829df577d14 342 Pfam PF01575 MaoC like domain 222 295 3.9E-18 T 06-07-2017 IPR002539 MaoC-like domain CAK77_RS23815 9f90be01d942ae9216316829df577d14 342 Gene3D G3DSA:3.10.129.10 197 326 2.5E-29 T 06-07-2017 IPR029069 HotDog domain CAK77_RS14670 7de313542d07f51541c45569276229ec 296 PIRSF PIRSF000097 4 270 4.2E-75 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAK77_RS14670 7de313542d07f51541c45569276229ec 296 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 43 60 - T 06-07-2017 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CAK77_RS14670 7de313542d07f51541c45569276229ec 296 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 230 245 - T 06-07-2017 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CAK77_RS14670 7de313542d07f51541c45569276229ec 296 Gene3D G3DSA:3.20.20.100 7 266 9.9E-91 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAK77_RS14670 7de313542d07f51541c45569276229ec 296 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 125 142 - T 06-07-2017 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CAK77_RS14670 7de313542d07f51541c45569276229ec 296 SUPERFAMILY SSF51430 8 272 1.15E-83 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAK77_RS14670 7de313542d07f51541c45569276229ec 296 Pfam PF00248 Aldo/keto reductase family 25 258 2.5E-46 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAK77_RS14670 7de313542d07f51541c45569276229ec 296 PRINTS PR00069 Aldo-keto reductase signature 93 111 6.1E-46 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAK77_RS14670 7de313542d07f51541c45569276229ec 296 PRINTS PR00069 Aldo-keto reductase signature 159 188 6.1E-46 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAK77_RS14670 7de313542d07f51541c45569276229ec 296 PRINTS PR00069 Aldo-keto reductase signature 197 221 6.1E-46 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAK77_RS14670 7de313542d07f51541c45569276229ec 296 PRINTS PR00069 Aldo-keto reductase signature 39 63 6.1E-46 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAK77_RS14670 7de313542d07f51541c45569276229ec 296 PRINTS PR00069 Aldo-keto reductase signature 125 142 6.1E-46 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAK77_RS01410 a48e27d342f903b780b6e5e57077b6a4 481 SUPERFAMILY SSF161098 274 461 9.29E-44 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS01410 a48e27d342f903b780b6e5e57077b6a4 481 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 297 476 3.6E-23 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS01410 a48e27d342f903b780b6e5e57077b6a4 481 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 26 242 3.3E-56 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAK77_RS01410 a48e27d342f903b780b6e5e57077b6a4 481 Gene3D G3DSA:3.40.190.10 104 203 3.9E-23 T 06-07-2017 CAK77_RS01410 a48e27d342f903b780b6e5e57077b6a4 481 SMART SM00062 25 244 3.0E-67 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAK77_RS01410 a48e27d342f903b780b6e5e57077b6a4 481 Gene3D G3DSA:1.10.3720.10 271 477 5.6E-49 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS01410 a48e27d342f903b780b6e5e57077b6a4 481 SUPERFAMILY SSF53850 4 243 3.33E-56 T 06-07-2017 CAK77_RS01410 a48e27d342f903b780b6e5e57077b6a4 481 Gene3D G3DSA:3.40.190.10 24 103 3.8E-35 T 06-07-2017 CAK77_RS01410 a48e27d342f903b780b6e5e57077b6a4 481 Gene3D G3DSA:3.40.190.10 204 244 3.8E-35 T 06-07-2017 CAK77_RS01410 a48e27d342f903b780b6e5e57077b6a4 481 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 49 62 - T 06-07-2017 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 CAK77_RS01410 a48e27d342f903b780b6e5e57077b6a4 481 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 280 370 3.6E-29 T 06-07-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CAK77_RS02240 87ac8c54aca970386a6c98c156ce1b22 174 Gene3D G3DSA:1.10.260.40 3 69 2.5E-17 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK77_RS02240 87ac8c54aca970386a6c98c156ce1b22 174 SMART SM00530 12 67 4.9E-13 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAK77_RS02240 87ac8c54aca970386a6c98c156ce1b22 174 SUPERFAMILY SSF47413 6 70 2.82E-14 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK77_RS02240 87ac8c54aca970386a6c98c156ce1b22 174 Pfam PF01381 Helix-turn-helix 13 67 4.1E-13 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAK77_RS12585 54046fc53a7861753bf6cb8467a468ba 279 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 136 164 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK77_RS12585 54046fc53a7861753bf6cb8467a468ba 279 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 180 5.0E-4 T 06-07-2017 CAK77_RS12585 54046fc53a7861753bf6cb8467a468ba 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 168 2.7E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS12585 54046fc53a7861753bf6cb8467a468ba 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 2.7E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS12585 54046fc53a7861753bf6cb8467a468ba 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 139 2.7E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS12585 54046fc53a7861753bf6cb8467a468ba 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 2.7E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS12585 54046fc53a7861753bf6cb8467a468ba 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 2.7E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS12585 54046fc53a7861753bf6cb8467a468ba 279 SUPERFAMILY SSF51735 3 239 1.17E-62 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS12585 54046fc53a7861753bf6cb8467a468ba 279 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 3.1E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS12585 54046fc53a7861753bf6cb8467a468ba 279 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 129 137 3.1E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS12585 54046fc53a7861753bf6cb8467a468ba 279 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 168 3.1E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS12585 54046fc53a7861753bf6cb8467a468ba 279 Pfam PF00106 short chain dehydrogenase 6 187 3.0E-51 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS12585 54046fc53a7861753bf6cb8467a468ba 279 Gene3D G3DSA:3.40.50.720 3 247 1.1E-64 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS10530 ba81b6dd10fd70135dc0ab99a3e50939 160 Gene3D G3DSA:1.10.10.10 96 155 2.5E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS10530 ba81b6dd10fd70135dc0ab99a3e50939 160 Pfam PF04545 Sigma-70, region 4 102 150 2.6E-12 T 06-07-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS10530 ba81b6dd10fd70135dc0ab99a3e50939 160 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 26 58 - T 06-07-2017 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS10530 ba81b6dd10fd70135dc0ab99a3e50939 160 SUPERFAMILY SSF88659 89 153 2.62E-13 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS10530 ba81b6dd10fd70135dc0ab99a3e50939 160 SUPERFAMILY SSF88946 2 86 7.46E-19 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS10530 ba81b6dd10fd70135dc0ab99a3e50939 160 Pfam PF04542 Sigma-70 region 2 4 71 4.3E-16 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS10530 ba81b6dd10fd70135dc0ab99a3e50939 160 Gene3D G3DSA:1.10.1740.10 2 92 2.6E-20 T 06-07-2017 CAK77_RS10530 ba81b6dd10fd70135dc0ab99a3e50939 160 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 2 151 4.1E-24 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS21240 186a69ba4cd9d4731c082cffebc37afb 293 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 69 182 4.3E-18 T 06-07-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CAK77_RS21240 186a69ba4cd9d4731c082cffebc37afb 293 Gene3D G3DSA:1.10.3720.10 65 287 1.5E-45 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS21240 186a69ba4cd9d4731c082cffebc37afb 293 SUPERFAMILY SSF161098 70 273 7.98E-42 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS21240 186a69ba4cd9d4731c082cffebc37afb 293 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 286 2.4E-22 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS13110 8971a8d59154fc1f91f287dffe62c8d4 342 Pfam PF02445 Quinolinate synthetase A protein 31 334 1.8E-109 T 06-07-2017 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 CAK77_RS13110 8971a8d59154fc1f91f287dffe62c8d4 342 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 29 335 2.3E-86 T 06-07-2017 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 CAK77_RS13110 8971a8d59154fc1f91f287dffe62c8d4 342 SUPERFAMILY SSF142754 28 335 1.83E-101 T 06-07-2017 CAK77_RS19135 8265a47f72bc6d11bc868e002e893d47 414 Pfam PF04055 Radical SAM superfamily 37 191 2.7E-25 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 CAK77_RS19135 8265a47f72bc6d11bc868e002e893d47 414 Pfam PF13353 4Fe-4S single cluster domain 38 134 1.1E-5 T 06-07-2017 CAK77_RS19135 8265a47f72bc6d11bc868e002e893d47 414 Gene3D G3DSA:3.20.20.70 30 340 2.2E-65 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK77_RS19135 8265a47f72bc6d11bc868e002e893d47 414 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 263 353 7.3E-14 T 06-07-2017 IPR023885 4Fe4S-binding SPASM domain CAK77_RS19135 8265a47f72bc6d11bc868e002e893d47 414 Pfam PF13186 Iron-sulfur cluster-binding domain 263 325 3.2E-5 T 06-07-2017 IPR023885 4Fe4S-binding SPASM domain CAK77_RS19135 8265a47f72bc6d11bc868e002e893d47 414 SMART SM00729 31 230 4.4E-4 T 06-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CAK77_RS19135 8265a47f72bc6d11bc868e002e893d47 414 SUPERFAMILY SSF102114 30 335 9.81E-62 T 06-07-2017 CAK77_RS19135 8265a47f72bc6d11bc868e002e893d47 414 TIGRFAM TIGR03962 mycofact_rSAM: mycofactocin radical SAM maturase 20 360 3.3E-202 T 06-07-2017 IPR023913 Mycofactocin, radical SAM peptide maturase CAK77_RS12680 6cac83155dbfacca1d8d35dc648c51e4 474 SUPERFAMILY SSF51679 4 446 2.22E-124 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS12680 6cac83155dbfacca1d8d35dc648c51e4 474 Pfam PF00296 Luciferase-like monooxygenase 21 396 3.0E-61 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS12680 6cac83155dbfacca1d8d35dc648c51e4 474 Gene3D G3DSA:3.20.20.30 357 446 5.1E-130 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS12680 6cac83155dbfacca1d8d35dc648c51e4 474 Gene3D G3DSA:3.20.20.30 2 316 5.1E-130 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS12680 6cac83155dbfacca1d8d35dc648c51e4 474 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 17 440 4.1E-156 T 06-07-2017 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 CAK77_RS12680 6cac83155dbfacca1d8d35dc648c51e4 474 PIRSF PIRSF000337 3 452 1.3E-177 T 06-07-2017 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 CAK77_RS00985 17390006144e1ee476ca22330a0de4c6 257 SUPERFAMILY SSF51735 14 252 1.54E-72 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS00985 17390006144e1ee476ca22330a0de4c6 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 182 3.7E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS00985 17390006144e1ee476ca22330a0de4c6 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 90 101 3.7E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS00985 17390006144e1ee476ca22330a0de4c6 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 184 201 3.7E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS00985 17390006144e1ee476ca22330a0de4c6 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 137 153 3.7E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS00985 17390006144e1ee476ca22330a0de4c6 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 16 33 3.7E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS00985 17390006144e1ee476ca22330a0de4c6 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 3.7E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS00985 17390006144e1ee476ca22330a0de4c6 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 143 151 3.5E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS00985 17390006144e1ee476ca22330a0de4c6 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 90 101 3.5E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS00985 17390006144e1ee476ca22330a0de4c6 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 163 182 3.5E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS00985 17390006144e1ee476ca22330a0de4c6 257 Gene3D G3DSA:3.40.50.720 7 252 5.6E-74 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS00985 17390006144e1ee476ca22330a0de4c6 257 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 23 252 1.0E-53 T 06-07-2017 CAK77_RS05035 0a788b7c8d88cad516e282d7d8a3e9f6 426 Gene3D G3DSA:3.40.47.10 9 128 2.4E-56 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS05035 0a788b7c8d88cad516e282d7d8a3e9f6 426 Gene3D G3DSA:3.40.47.10 217 289 2.4E-56 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS05035 0a788b7c8d88cad516e282d7d8a3e9f6 426 ProSitePatterns PS00737 Thiolases signature 2. 371 387 - T 06-07-2017 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CAK77_RS05035 0a788b7c8d88cad516e282d7d8a3e9f6 426 PIRSF PIRSF000429 3 426 7.1E-120 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 CAK77_RS05035 0a788b7c8d88cad516e282d7d8a3e9f6 426 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 11 423 4.8E-122 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 CAK77_RS05035 0a788b7c8d88cad516e282d7d8a3e9f6 426 Pfam PF02803 Thiolase, C-terminal domain 285 424 6.0E-39 T 06-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CAK77_RS05035 0a788b7c8d88cad516e282d7d8a3e9f6 426 SUPERFAMILY SSF53901 9 284 1.35E-66 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS05035 0a788b7c8d88cad516e282d7d8a3e9f6 426 ProSitePatterns PS00099 Thiolases active site. 406 419 - T 06-07-2017 IPR020610 Thiolase, active site GO:0008152|GO:0016747 CAK77_RS05035 0a788b7c8d88cad516e282d7d8a3e9f6 426 Gene3D G3DSA:3.40.47.10 291 424 5.4E-49 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS05035 0a788b7c8d88cad516e282d7d8a3e9f6 426 Gene3D G3DSA:3.40.47.10 171 216 5.4E-49 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS05035 0a788b7c8d88cad516e282d7d8a3e9f6 426 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 89 107 - T 06-07-2017 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 CAK77_RS05035 0a788b7c8d88cad516e282d7d8a3e9f6 426 Pfam PF00108 Thiolase, N-terminal domain 10 277 8.0E-65 T 06-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CAK77_RS05035 0a788b7c8d88cad516e282d7d8a3e9f6 426 SUPERFAMILY SSF53901 285 424 7.88E-34 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS23470 e0a966cb58bd0a728186d192b532ca54 231 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 103 187 8.1E-13 T 06-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAK77_RS23470 e0a966cb58bd0a728186d192b532ca54 231 SUPERFAMILY SSF50475 101 219 7.52E-17 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS23470 e0a966cb58bd0a728186d192b532ca54 231 Gene3D G3DSA:2.30.110.10 97 218 3.9E-32 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS23340 c4b20fc1e90bb4ba99c6607711dea152 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 2.6E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS23340 c4b20fc1e90bb4ba99c6607711dea152 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 2.6E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS23340 c4b20fc1e90bb4ba99c6607711dea152 220 Gene3D G3DSA:1.10.10.60 3 67 2.0E-22 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS23340 c4b20fc1e90bb4ba99c6607711dea152 220 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 77 215 3.2E-18 T 06-07-2017 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 CAK77_RS23340 c4b20fc1e90bb4ba99c6607711dea152 220 SUPERFAMILY SSF46689 6 72 2.29E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS23340 c4b20fc1e90bb4ba99c6607711dea152 220 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 63 6.2E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS23340 c4b20fc1e90bb4ba99c6607711dea152 220 Gene3D G3DSA:1.10.357.10 68 217 6.7E-31 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS23340 c4b20fc1e90bb4ba99c6607711dea152 220 SUPERFAMILY SSF48498 83 219 2.0E-27 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS19020 1d9a366fecacb35afcad033e76a72422 105 Pfam PF00366 Ribosomal protein S17 32 99 1.6E-27 T 06-07-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS19020 1d9a366fecacb35afcad033e76a72422 105 SUPERFAMILY SSF50249 26 104 1.54E-27 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS19020 1d9a366fecacb35afcad033e76a72422 105 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 27 98 2.3E-31 T 06-07-2017 IPR019984 Ribosomal protein S17, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS19020 1d9a366fecacb35afcad033e76a72422 105 PRINTS PR00973 Ribosomal protein S17 family signature 88 95 2.9E-10 T 06-07-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS19020 1d9a366fecacb35afcad033e76a72422 105 PRINTS PR00973 Ribosomal protein S17 family signature 78 88 2.9E-10 T 06-07-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS19020 1d9a366fecacb35afcad033e76a72422 105 PRINTS PR00973 Ribosomal protein S17 family signature 46 69 2.9E-10 T 06-07-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS19020 1d9a366fecacb35afcad033e76a72422 105 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 25 103 23.123 T 06-07-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS19020 1d9a366fecacb35afcad033e76a72422 105 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 27 98 2.0E-29 T 06-07-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS19020 1d9a366fecacb35afcad033e76a72422 105 Gene3D G3DSA:2.40.50.140 26 104 5.9E-32 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS23975 ec4d7783242406c2b30044a653204466 294 SUPERFAMILY SSF53697 114 276 3.5E-29 T 06-07-2017 CAK77_RS23975 ec4d7783242406c2b30044a653204466 294 SUPERFAMILY SSF46689 20 89 4.66E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS23975 ec4d7783242406c2b30044a653204466 294 Gene3D G3DSA:3.40.50.10490 122 276 3.1E-31 T 06-07-2017 CAK77_RS23975 ec4d7783242406c2b30044a653204466 294 Gene3D G3DSA:1.10.10.10 20 89 2.8E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS23975 ec4d7783242406c2b30044a653204466 294 Pfam PF01380 SIS domain 142 270 1.2E-17 T 06-07-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 CAK77_RS23975 ec4d7783242406c2b30044a653204466 294 Pfam PF01418 Helix-turn-helix domain, rpiR family 22 88 2.0E-13 T 06-07-2017 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 CAK77_RS03530 a0700dfeca9d9898c158d1c4f75a5cd4 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 60 1.2E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS03530 a0700dfeca9d9898c158d1c4f75a5cd4 204 SUPERFAMILY SSF46689 9 89 8.48E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS03530 a0700dfeca9d9898c158d1c4f75a5cd4 204 Gene3D G3DSA:1.10.357.10 9 202 1.5E-22 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS03530 a0700dfeca9d9898c158d1c4f75a5cd4 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 35 6.2E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS03530 a0700dfeca9d9898c158d1c4f75a5cd4 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 66 6.2E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS02820 db193af6222da194e6c8aa48dbdf2c7e 141 SUPERFAMILY SSF50692 2 117 8.12E-50 T 06-07-2017 IPR009010 Aspartate decarboxylase-like domain CAK77_RS02820 db193af6222da194e6c8aa48dbdf2c7e 141 TIGRFAM TIGR00223 panD: aspartate 1-decarboxylase 2 118 3.7E-52 T 06-07-2017 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 CAK77_RS02820 db193af6222da194e6c8aa48dbdf2c7e 141 ProDom PD009294 ASPARTATE 1-DECARBOXYLASE DECARBOXYLASE CHAIN LYASE ALPHA ALPHA- CONTAINS: PRECURSOR BETA 6 96 1.0E-39 T 06-07-2017 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 CAK77_RS02820 db193af6222da194e6c8aa48dbdf2c7e 141 Hamap MF_00446 Aspartate 1-decarboxylase [panD]. 1 130 73.474 T 06-07-2017 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 CAK77_RS02820 db193af6222da194e6c8aa48dbdf2c7e 141 Pfam PF02261 Aspartate decarboxylase 2 114 1.6E-52 T 06-07-2017 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 CAK77_RS02820 db193af6222da194e6c8aa48dbdf2c7e 141 Gene3D G3DSA:2.40.40.20 2 120 1.6E-56 T 06-07-2017 CAK77_RS02820 db193af6222da194e6c8aa48dbdf2c7e 141 PIRSF PIRSF006246 2 131 1.6E-53 T 06-07-2017 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 CAK77_RS23290 036fdd54235012e804b689a7d645b558 139 Gene3D G3DSA:2.30.110.10 6 137 3.9E-20 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS23290 036fdd54235012e804b689a7d645b558 139 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 26 92 1.5E-8 T 06-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAK77_RS23290 036fdd54235012e804b689a7d645b558 139 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 10 136 2.7E-24 T 06-07-2017 IPR019920 F420-binding domain, putative CAK77_RS23290 036fdd54235012e804b689a7d645b558 139 SUPERFAMILY SSF50475 5 136 1.7E-21 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS06095 3badf5f4a0ac420bc7278c9b8282ad99 453 SUPERFAMILY SSF48264 16 451 1.31E-96 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS06095 3badf5f4a0ac420bc7278c9b8282ad99 453 Pfam PF00067 Cytochrome P450 17 446 8.5E-67 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS06095 3badf5f4a0ac420bc7278c9b8282ad99 453 Gene3D G3DSA:1.10.630.10 17 451 5.9E-97 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS06095 3badf5f4a0ac420bc7278c9b8282ad99 453 PRINTS PR00385 P450 superfamily signature 397 408 2.7E-11 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS06095 3badf5f4a0ac420bc7278c9b8282ad99 453 PRINTS PR00385 P450 superfamily signature 259 276 2.7E-11 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS06095 3badf5f4a0ac420bc7278c9b8282ad99 453 PRINTS PR00385 P450 superfamily signature 388 397 2.7E-11 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS06095 3badf5f4a0ac420bc7278c9b8282ad99 453 PRINTS PR00385 P450 superfamily signature 312 323 2.7E-11 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS06095 3badf5f4a0ac420bc7278c9b8282ad99 453 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 390 399 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CAK77_RS06095 3badf5f4a0ac420bc7278c9b8282ad99 453 PRINTS PR00465 E-class P450 group IV signature 340 354 3.9E-30 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS06095 3badf5f4a0ac420bc7278c9b8282ad99 453 PRINTS PR00465 E-class P450 group IV signature 250 276 3.9E-30 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS06095 3badf5f4a0ac420bc7278c9b8282ad99 453 PRINTS PR00465 E-class P450 group IV signature 381 397 3.9E-30 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS06095 3badf5f4a0ac420bc7278c9b8282ad99 453 PRINTS PR00465 E-class P450 group IV signature 28 51 3.9E-30 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS06095 3badf5f4a0ac420bc7278c9b8282ad99 453 PRINTS PR00465 E-class P450 group IV signature 397 415 3.9E-30 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS06095 3badf5f4a0ac420bc7278c9b8282ad99 453 PRINTS PR00465 E-class P450 group IV signature 356 374 3.9E-30 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS06095 3badf5f4a0ac420bc7278c9b8282ad99 453 PRINTS PR00465 E-class P450 group IV signature 307 323 3.9E-30 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS07630 605203f470efe8629706a098b265f377 157 Gene3D G3DSA:3.40.30.10 3 155 2.4E-51 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK77_RS07630 605203f470efe8629706a098b265f377 157 PIRSF PIRSF000239 2 155 7.3E-21 T 06-07-2017 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CAK77_RS07630 605203f470efe8629706a098b265f377 157 Pfam PF00578 AhpC/TSA family 9 136 4.7E-40 T 06-07-2017 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CAK77_RS07630 605203f470efe8629706a098b265f377 157 SUPERFAMILY SSF52833 6 155 6.06E-49 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK77_RS16905 71255d826f302b5b25439d1e4775d34b 623 SUPERFAMILY SSF90123 66 383 8.24E-13 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAK77_RS16905 71255d826f302b5b25439d1e4775d34b 623 SUPERFAMILY SSF90123 546 555 8.24E-13 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAK77_RS16905 71255d826f302b5b25439d1e4775d34b 623 Gene3D G3DSA:3.40.50.300 419 600 5.8E-32 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS16905 71255d826f302b5b25439d1e4775d34b 623 ProSitePatterns PS00211 ABC transporters family signature. 542 556 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK77_RS16905 71255d826f302b5b25439d1e4775d34b 623 Pfam PF00005 ABC transporter 435 570 3.8E-15 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK77_RS16905 71255d826f302b5b25439d1e4775d34b 623 Pfam PF06472 ABC transporter transmembrane region 2 40 349 9.1E-72 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAK77_RS16905 71255d826f302b5b25439d1e4775d34b 623 SUPERFAMILY SSF52540 418 605 1.07E-32 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS16905 71255d826f302b5b25439d1e4775d34b 623 SMART SM00382 443 617 9.4E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS16905 71255d826f302b5b25439d1e4775d34b 623 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 447 460 - T 06-07-2017 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 CAK77_RS07945 4bc1a5b1bc7ffade24a93ade201b45b3 265 SUPERFAMILY SSF81624 2 123 4.71E-20 T 06-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CAK77_RS07945 4bc1a5b1bc7ffade24a93ade201b45b3 265 Gene3D G3DSA:1.10.8.50 123 263 2.9E-45 T 06-07-2017 CAK77_RS07945 4bc1a5b1bc7ffade24a93ade201b45b3 265 SUPERFAMILY SSF46946 121 206 4.27E-25 T 06-07-2017 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 CAK77_RS07945 4bc1a5b1bc7ffade24a93ade201b45b3 265 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 122 208 1.5E-23 T 06-07-2017 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 CAK77_RS07945 4bc1a5b1bc7ffade24a93ade201b45b3 265 ProSitePatterns PS01242 Zinc finger FPG-type signature. 239 263 - T 06-07-2017 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 CAK77_RS07945 4bc1a5b1bc7ffade24a93ade201b45b3 265 SMART SM00898 2 108 1.1E-15 T 06-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CAK77_RS07945 4bc1a5b1bc7ffade24a93ade201b45b3 265 Gene3D G3DSA:3.20.190.10 2 122 1.7E-12 T 06-07-2017 CAK77_RS07945 4bc1a5b1bc7ffade24a93ade201b45b3 265 Pfam PF06827 Zinc finger found in FPG and IleRS 236 263 5.8E-9 T 06-07-2017 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 CAK77_RS07945 4bc1a5b1bc7ffade24a93ade201b45b3 265 SMART SM01232 122 214 1.9E-34 T 06-07-2017 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 CAK77_RS07945 4bc1a5b1bc7ffade24a93ade201b45b3 265 SUPERFAMILY SSF57716 228 263 2.09E-11 T 06-07-2017 CAK77_RS18705 2b714f362e379bde1ad03dc11ae43f7a 438 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 152 247 7.9E-18 T 06-07-2017 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK77_RS18705 2b714f362e379bde1ad03dc11ae43f7a 438 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 167 186 5.5E-10 T 06-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK77_RS18705 2b714f362e379bde1ad03dc11ae43f7a 438 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 227 242 5.5E-10 T 06-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK77_RS18705 2b714f362e379bde1ad03dc11ae43f7a 438 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 90 104 5.5E-10 T 06-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK77_RS18705 2b714f362e379bde1ad03dc11ae43f7a 438 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 130 1.7E-40 T 06-07-2017 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK77_RS18705 2b714f362e379bde1ad03dc11ae43f7a 438 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 1 438 41.894 T 06-07-2017 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK77_RS18705 2b714f362e379bde1ad03dc11ae43f7a 438 Gene3D G3DSA:3.40.120.10 170 243 8.9E-24 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK77_RS18705 2b714f362e379bde1ad03dc11ae43f7a 438 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 251 359 1.0E-29 T 06-07-2017 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK77_RS18705 2b714f362e379bde1ad03dc11ae43f7a 438 Gene3D G3DSA:3.40.120.10 244 361 1.1E-31 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK77_RS18705 2b714f362e379bde1ad03dc11ae43f7a 438 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 4 435 4.3E-175 T 06-07-2017 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK77_RS18705 2b714f362e379bde1ad03dc11ae43f7a 438 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 91 100 - T 06-07-2017 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK77_RS18705 2b714f362e379bde1ad03dc11ae43f7a 438 Gene3D G3DSA:3.30.310.50 363 435 4.8E-20 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK77_RS18705 2b714f362e379bde1ad03dc11ae43f7a 438 SUPERFAMILY SSF55957 351 437 9.16E-23 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK77_RS18705 2b714f362e379bde1ad03dc11ae43f7a 438 SUPERFAMILY SSF53738 3 174 4.32E-44 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK77_RS18705 2b714f362e379bde1ad03dc11ae43f7a 438 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 367 434 6.3E-16 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK77_RS18705 2b714f362e379bde1ad03dc11ae43f7a 438 SUPERFAMILY SSF53738 150 250 3.61E-25 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK77_RS18705 2b714f362e379bde1ad03dc11ae43f7a 438 Gene3D G3DSA:3.40.120.10 3 144 5.9E-42 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK77_RS18705 2b714f362e379bde1ad03dc11ae43f7a 438 SUPERFAMILY SSF53738 251 359 7.06E-27 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK77_RS16695 e13f31b43d4f4084b9d875686a09ca81 396 Gene3D G3DSA:3.40.640.10 17 251 3.7E-67 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK77_RS16695 e13f31b43d4f4084b9d875686a09ca81 396 SUPERFAMILY SSF53383 5 381 1.41E-86 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK77_RS16695 e13f31b43d4f4084b9d875686a09ca81 396 Gene3D G3DSA:3.90.1150.10 252 378 4.2E-38 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK77_RS16695 e13f31b43d4f4084b9d875686a09ca81 396 Pfam PF00266 Aminotransferase class-V 5 372 2.7E-56 T 06-07-2017 IPR000192 Aminotransferase class V domain CAK77_RS16695 e13f31b43d4f4084b9d875686a09ca81 396 PIRSF PIRSF005572 2 388 6.5E-107 T 06-07-2017 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 CAK77_RS08025 881ee0f2f2a95aad20300c8972bf3392 250 Pfam PF13936 Helix-turn-helix domain 82 116 6.3E-7 T 06-07-2017 IPR025246 Transposase IS30-like HTH domain CAK77_RS08025 881ee0f2f2a95aad20300c8972bf3392 250 Gene3D G3DSA:1.10.10.10 81 123 2.3E-4 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS19210 96d398fcf552b54101fa45639e840d55 701 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 12 182 9.8E-39 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 CAK77_RS19210 96d398fcf552b54101fa45639e840d55 701 Gene3D G3DSA:3.30.70.870 408 483 3.2E-38 T 06-07-2017 CAK77_RS19210 96d398fcf552b54101fa45639e840d55 701 Pfam PF00009 Elongation factor Tu GTP binding domain 11 284 2.9E-69 T 06-07-2017 CAK77_RS19210 96d398fcf552b54101fa45639e840d55 701 Hamap MF_00054_B Elongation factor G [fusA]. 8 698 109.63 T 06-07-2017 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CAK77_RS19210 96d398fcf552b54101fa45639e840d55 701 SMART SM00889 483 605 6.1E-70 T 06-07-2017 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 CAK77_RS19210 96d398fcf552b54101fa45639e840d55 701 Pfam PF03144 Elongation factor Tu domain 2 327 394 4.9E-15 T 06-07-2017 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CAK77_RS19210 96d398fcf552b54101fa45639e840d55 701 Gene3D G3DSA:3.30.70.240 605 697 6.2E-33 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain CAK77_RS19210 96d398fcf552b54101fa45639e840d55 701 Pfam PF00679 Elongation factor G C-terminus 607 693 3.7E-30 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain CAK77_RS19210 96d398fcf552b54101fa45639e840d55 701 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 53 68 - T 06-07-2017 IPR031157 Tr-type G domain, conserved site CAK77_RS19210 96d398fcf552b54101fa45639e840d55 701 PRINTS PR00315 GTP-binding elongation factor signature 60 68 1.9E-16 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAK77_RS19210 96d398fcf552b54101fa45639e840d55 701 PRINTS PR00315 GTP-binding elongation factor signature 80 90 1.9E-16 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAK77_RS19210 96d398fcf552b54101fa45639e840d55 701 PRINTS PR00315 GTP-binding elongation factor signature 132 141 1.9E-16 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAK77_RS19210 96d398fcf552b54101fa45639e840d55 701 PRINTS PR00315 GTP-binding elongation factor signature 14 27 1.9E-16 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAK77_RS19210 96d398fcf552b54101fa45639e840d55 701 PRINTS PR00315 GTP-binding elongation factor signature 96 107 1.9E-16 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAK77_RS19210 96d398fcf552b54101fa45639e840d55 701 SUPERFAMILY SSF54980 407 484 6.12E-25 T 06-07-2017 IPR009022 Elongation factor G, III-V domain CAK77_RS19210 96d398fcf552b54101fa45639e840d55 701 Pfam PF03764 Elongation factor G, domain IV 482 605 7.2E-47 T 06-07-2017 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 CAK77_RS19210 96d398fcf552b54101fa45639e840d55 701 Pfam PF14492 Elongation Factor G, domain II 407 481 3.1E-34 T 06-07-2017 IPR009022 Elongation factor G, III-V domain CAK77_RS19210 96d398fcf552b54101fa45639e840d55 701 SUPERFAMILY SSF54980 610 696 1.25E-29 T 06-07-2017 IPR009022 Elongation factor G, III-V domain CAK77_RS19210 96d398fcf552b54101fa45639e840d55 701 TIGRFAM TIGR00484 EF-G: translation elongation factor G 7 698 0.0 T 06-07-2017 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CAK77_RS19210 96d398fcf552b54101fa45639e840d55 701 Gene3D G3DSA:3.40.50.300 8 289 2.5E-106 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS19210 96d398fcf552b54101fa45639e840d55 701 SUPERFAMILY SSF54211 482 606 8.09E-40 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAK77_RS19210 96d398fcf552b54101fa45639e840d55 701 SUPERFAMILY SSF52540 8 284 1.59E-108 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS19210 96d398fcf552b54101fa45639e840d55 701 SUPERFAMILY SSF50447 267 407 2.78E-34 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain CAK77_RS19210 96d398fcf552b54101fa45639e840d55 701 Gene3D G3DSA:2.40.30.10 309 407 4.2E-36 T 06-07-2017 CAK77_RS19210 96d398fcf552b54101fa45639e840d55 701 SMART SM00838 607 694 7.8E-57 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain CAK77_RS19210 96d398fcf552b54101fa45639e840d55 701 Gene3D G3DSA:3.30.230.10 487 604 8.6E-47 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CAK77_RS07795 74be2b91c10ca9233354473cf7921ad0 453 SUPERFAMILY SSF53649 5 414 3.05E-86 T 06-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CAK77_RS07795 74be2b91c10ca9233354473cf7921ad0 453 ProSitePatterns PS00523 Sulfatases signature 1. 52 64 - T 06-07-2017 IPR024607 Sulfatase, conserved site CAK77_RS07795 74be2b91c10ca9233354473cf7921ad0 453 Pfam PF00884 Sulfatase 8 280 3.0E-43 T 06-07-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 CAK77_RS07795 74be2b91c10ca9233354473cf7921ad0 453 Gene3D G3DSA:3.40.720.10 5 322 1.4E-66 T 06-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CAK77_RS07795 74be2b91c10ca9233354473cf7921ad0 453 Gene3D G3DSA:3.30.1120.10 323 414 8.8E-15 T 06-07-2017 CAK77_RS01175 957ed5c9cfbbe1a5f11345ac79b9c955 312 SUPERFAMILY SSF53448 7 278 9.72E-33 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK77_RS01175 957ed5c9cfbbe1a5f11345ac79b9c955 312 Gene3D G3DSA:3.90.550.10 12 220 8.3E-17 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK77_RS01175 957ed5c9cfbbe1a5f11345ac79b9c955 312 Pfam PF13641 Glycosyltransferase like family 2 9 252 6.0E-9 T 06-07-2017 CAK77_RS15365 080571046a013b045a6e840678048bc1 177 SMART SM00867 3 175 5.6E-12 T 06-07-2017 IPR007372 Lipid/polyisoprenoid-binding, YceI-like CAK77_RS15365 080571046a013b045a6e840678048bc1 177 SUPERFAMILY SSF101874 3 172 9.42E-19 T 06-07-2017 IPR007372 Lipid/polyisoprenoid-binding, YceI-like CAK77_RS15365 080571046a013b045a6e840678048bc1 177 Gene3D G3DSA:2.40.128.110 4 171 5.6E-19 T 06-07-2017 IPR007372 Lipid/polyisoprenoid-binding, YceI-like CAK77_RS15365 080571046a013b045a6e840678048bc1 177 Pfam PF04264 YceI-like domain 4 171 1.0E-14 T 06-07-2017 IPR007372 Lipid/polyisoprenoid-binding, YceI-like CAK77_RS08735 429d8a283f2bb832db1c904d7b823e48 673 SMART SM00382 252 425 1.3E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS08735 429d8a283f2bb832db1c904d7b823e48 673 SMART SM00382 483 660 1.1E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS08735 429d8a283f2bb832db1c904d7b823e48 673 Gene3D G3DSA:3.40.50.300 453 662 2.9E-45 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS08735 429d8a283f2bb832db1c904d7b823e48 673 SUPERFAMILY SSF52540 222 422 1.66E-38 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS08735 429d8a283f2bb832db1c904d7b823e48 673 Pfam PF00005 ABC transporter 474 611 3.4E-21 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK77_RS08735 429d8a283f2bb832db1c904d7b823e48 673 Pfam PF00005 ABC transporter 245 377 7.4E-20 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK77_RS08735 429d8a283f2bb832db1c904d7b823e48 673 SUPERFAMILY SSF52540 446 662 1.89E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS08735 429d8a283f2bb832db1c904d7b823e48 673 Gene3D G3DSA:3.40.50.300 228 422 3.2E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS08735 429d8a283f2bb832db1c904d7b823e48 673 ProSitePatterns PS00211 ABC transporters family signature. 584 598 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK77_RS08735 429d8a283f2bb832db1c904d7b823e48 673 ProSitePatterns PS00211 ABC transporters family signature. 349 363 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK77_RS14110 6999be94486f45404654baf529b7eb52 182 ProSitePatterns PS01321 Crossover junction endodeoxyribonuclease ruvC signature. 111 146 - T 06-07-2017 IPR020563 Crossover junction endodeoxyribonuclease RuvC, magnesium-binding site GO:0008821 CAK77_RS14110 6999be94486f45404654baf529b7eb52 182 SUPERFAMILY SSF53098 1 155 1.74E-42 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAK77_RS14110 6999be94486f45404654baf529b7eb52 182 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 59 75 3.1E-38 T 06-07-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CAK77_RS14110 6999be94486f45404654baf529b7eb52 182 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 105 124 3.1E-38 T 06-07-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CAK77_RS14110 6999be94486f45404654baf529b7eb52 182 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 1 14 3.1E-38 T 06-07-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CAK77_RS14110 6999be94486f45404654baf529b7eb52 182 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 137 149 3.1E-38 T 06-07-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CAK77_RS14110 6999be94486f45404654baf529b7eb52 182 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 81 97 3.1E-38 T 06-07-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CAK77_RS14110 6999be94486f45404654baf529b7eb52 182 TIGRFAM TIGR00228 ruvC: crossover junction endodeoxyribonuclease RuvC 1 152 3.3E-34 T 06-07-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CAK77_RS14110 6999be94486f45404654baf529b7eb52 182 Pfam PF02075 Crossover junction endodeoxyribonuclease RuvC 1 149 2.0E-60 T 06-07-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CAK77_RS14110 6999be94486f45404654baf529b7eb52 182 Gene3D G3DSA:3.30.420.10 1 154 1.5E-54 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAK77_RS14110 6999be94486f45404654baf529b7eb52 182 Hamap MF_00034 Crossover junction endodeoxyribonuclease RuvC [ruvC]. 1 152 43.596 T 06-07-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CAK77_RS03270 4556643a8b3d40e775673d7c843be9a8 97 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 31 80 1.4E-11 T 06-07-2017 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 CAK77_RS20065 85d9d9fbf5556f1496071f965a7bcbbb 299 SUPERFAMILY SSF51735 7 171 8.79E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS20065 85d9d9fbf5556f1496071f965a7bcbbb 299 Gene3D G3DSA:3.40.50.720 5 171 8.5E-41 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS20065 85d9d9fbf5556f1496071f965a7bcbbb 299 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 6 294 27.478 T 06-07-2017 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CAK77_RS20065 85d9d9fbf5556f1496071f965a7bcbbb 299 SUPERFAMILY SSF48179 173 295 3.74E-29 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAK77_RS20065 85d9d9fbf5556f1496071f965a7bcbbb 299 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 8 294 9.2E-80 T 06-07-2017 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CAK77_RS20065 85d9d9fbf5556f1496071f965a7bcbbb 299 PIRSF PIRSF000193 5 297 1.9E-59 T 06-07-2017 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CAK77_RS20065 85d9d9fbf5556f1496071f965a7bcbbb 299 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 7 110 3.1E-21 T 06-07-2017 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal CAK77_RS20065 85d9d9fbf5556f1496071f965a7bcbbb 299 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 250 272 - T 06-07-2017 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CAK77_RS20065 85d9d9fbf5556f1496071f965a7bcbbb 299 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 173 294 1.8E-39 T 06-07-2017 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 CAK77_RS20065 85d9d9fbf5556f1496071f965a7bcbbb 299 Gene3D G3DSA:1.10.3730.10 173 294 2.9E-37 T 06-07-2017 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 CAK77_RS19205 92d2f507c89e603e1da565c51d63c17d 397 Pfam PF00009 Elongation factor Tu GTP binding domain 10 203 1.2E-58 T 06-07-2017 CAK77_RS19205 92d2f507c89e603e1da565c51d63c17d 397 Pfam PF03144 Elongation factor Tu domain 2 227 296 1.7E-16 T 06-07-2017 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CAK77_RS19205 92d2f507c89e603e1da565c51d63c17d 397 Gene3D G3DSA:3.40.50.300 5 213 2.8E-69 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS19205 92d2f507c89e603e1da565c51d63c17d 397 PRINTS PR00315 GTP-binding elongation factor signature 80 90 1.6E-23 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAK77_RS19205 92d2f507c89e603e1da565c51d63c17d 397 PRINTS PR00315 GTP-binding elongation factor signature 60 68 1.6E-23 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAK77_RS19205 92d2f507c89e603e1da565c51d63c17d 397 PRINTS PR00315 GTP-binding elongation factor signature 14 27 1.6E-23 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAK77_RS19205 92d2f507c89e603e1da565c51d63c17d 397 PRINTS PR00315 GTP-binding elongation factor signature 96 107 1.6E-23 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAK77_RS19205 92d2f507c89e603e1da565c51d63c17d 397 PRINTS PR00315 GTP-binding elongation factor signature 133 142 1.6E-23 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAK77_RS19205 92d2f507c89e603e1da565c51d63c17d 397 SUPERFAMILY SSF52540 6 221 8.99E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS19205 92d2f507c89e603e1da565c51d63c17d 397 SUPERFAMILY SSF50465 305 397 5.76E-35 T 06-07-2017 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal CAK77_RS19205 92d2f507c89e603e1da565c51d63c17d 397 Pfam PF03143 Elongation factor Tu C-terminal domain 302 395 1.2E-31 T 06-07-2017 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal CAK77_RS19205 92d2f507c89e603e1da565c51d63c17d 397 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 150 1.7E-13 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 CAK77_RS19205 92d2f507c89e603e1da565c51d63c17d 397 Gene3D G3DSA:2.40.30.10 303 396 2.7E-45 T 06-07-2017 CAK77_RS19205 92d2f507c89e603e1da565c51d63c17d 397 Gene3D G3DSA:2.40.30.10 214 301 3.0E-35 T 06-07-2017 CAK77_RS19205 92d2f507c89e603e1da565c51d63c17d 397 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 53 68 - T 06-07-2017 IPR031157 Tr-type G domain, conserved site CAK77_RS19205 92d2f507c89e603e1da565c51d63c17d 397 SUPERFAMILY SSF50447 207 304 8.73E-30 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain CAK77_RS19205 92d2f507c89e603e1da565c51d63c17d 397 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 2 397 3.0E-219 T 06-07-2017 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CAK77_RS19205 92d2f507c89e603e1da565c51d63c17d 397 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 397 59.278 T 06-07-2017 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CAK77_RS19320 64a7cc77de83778c92b09ba0b0b6b17b 382 Pfam PF00005 ABC transporter 28 175 5.9E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK77_RS19320 64a7cc77de83778c92b09ba0b0b6b17b 382 SUPERFAMILY SSF52540 13 239 2.44E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS19320 64a7cc77de83778c92b09ba0b0b6b17b 382 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK77_RS19320 64a7cc77de83778c92b09ba0b0b6b17b 382 Gene3D G3DSA:3.40.50.300 12 240 1.3E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS19320 64a7cc77de83778c92b09ba0b0b6b17b 382 SMART SM00382 36 232 4.7E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS10600 386e8ea727b4bdc3d8500d2216a74b60 342 SUPERFAMILY SSF53850 31 258 1.68E-37 T 06-07-2017 CAK77_RS10600 386e8ea727b4bdc3d8500d2216a74b60 342 Pfam PF09084 NMT1/THI5 like 117 256 6.3E-14 T 06-07-2017 IPR015168 SsuA/THI5-like CAK77_RS10600 386e8ea727b4bdc3d8500d2216a74b60 342 Gene3D G3DSA:3.40.190.10 119 238 2.6E-22 T 06-07-2017 CAK77_RS10600 386e8ea727b4bdc3d8500d2216a74b60 342 SMART SM00062 33 264 0.0038 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAK77_RS04685 4ab049acf2335533f634c0316b12ee0d 273 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 69 1.9E-15 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK77_RS04685 4ab049acf2335533f634c0316b12ee0d 273 SUPERFAMILY SSF64288 60 239 1.13E-45 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CAK77_RS04685 4ab049acf2335533f634c0316b12ee0d 273 Pfam PF07702 UTRA domain 97 234 4.8E-42 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CAK77_RS04685 4ab049acf2335533f634c0316b12ee0d 273 SMART SM00866 95 234 8.2E-40 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CAK77_RS04685 4ab049acf2335533f634c0316b12ee0d 273 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 32 46 1.3E-7 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK77_RS04685 4ab049acf2335533f634c0316b12ee0d 273 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 46 62 1.3E-7 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK77_RS04685 4ab049acf2335533f634c0316b12ee0d 273 SUPERFAMILY SSF46785 4 76 1.82E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS04685 4ab049acf2335533f634c0316b12ee0d 273 SMART SM00345 13 74 1.5E-14 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK77_RS04685 4ab049acf2335533f634c0316b12ee0d 273 Gene3D G3DSA:1.10.10.10 5 68 5.0E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS04685 4ab049acf2335533f634c0316b12ee0d 273 Gene3D G3DSA:3.40.1410.10 69 239 2.0E-47 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CAK77_RS13220 2886430fbdefd37d6e46b699b480b414 305 SUPERFAMILY SSF103481 191 290 9.55E-10 T 06-07-2017 CAK77_RS13220 2886430fbdefd37d6e46b699b480b414 305 Pfam PF00892 EamA-like transporter family 16 150 5.0E-11 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAK77_RS13220 2886430fbdefd37d6e46b699b480b414 305 SUPERFAMILY SSF103481 54 151 7.45E-12 T 06-07-2017 CAK77_RS13220 2886430fbdefd37d6e46b699b480b414 305 TIGRFAM TIGR00688 rarD: protein RarD 16 265 1.8E-58 T 06-07-2017 IPR004626 RarD protein GO:0005215|GO:0005887|GO:0006810 CAK77_RS21025 416431caeb07ddc35b31c5d0279d5576 578 Pfam PF07690 Major Facilitator Superfamily 40 332 4.1E-26 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK77_RS21025 416431caeb07ddc35b31c5d0279d5576 578 SUPERFAMILY SSF103473 286 464 5.75E-51 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK77_RS21025 416431caeb07ddc35b31c5d0279d5576 578 SUPERFAMILY SSF103473 546 567 5.75E-51 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK77_RS21025 416431caeb07ddc35b31c5d0279d5576 578 SUPERFAMILY SSF103473 29 234 5.75E-51 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK77_RS21025 416431caeb07ddc35b31c5d0279d5576 578 Gene3D G3DSA:1.20.1250.20 39 219 2.4E-24 T 06-07-2017 CAK77_RS21025 416431caeb07ddc35b31c5d0279d5576 578 Gene3D G3DSA:1.20.1250.20 298 488 4.0E-18 T 06-07-2017 CAK77_RS13105 8933ddbdeba105cfceac8a4048cb0eb7 523 SUPERFAMILY SSF56425 227 341 1.0E-32 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK77_RS13105 8933ddbdeba105cfceac8a4048cb0eb7 523 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 12 494 9.8E-175 T 06-07-2017 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 CAK77_RS13105 8933ddbdeba105cfceac8a4048cb0eb7 523 Gene3D G3DSA:1.20.58.100 400 494 6.5E-12 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK77_RS13105 8933ddbdeba105cfceac8a4048cb0eb7 523 Gene3D G3DSA:3.50.50.60 338 399 6.9E-86 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS13105 8933ddbdeba105cfceac8a4048cb0eb7 523 Gene3D G3DSA:3.50.50.60 6 232 6.9E-86 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS13105 8933ddbdeba105cfceac8a4048cb0eb7 523 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 257 279 6.9E-8 T 06-07-2017 CAK77_RS13105 8933ddbdeba105cfceac8a4048cb0eb7 523 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 15 34 6.9E-8 T 06-07-2017 CAK77_RS13105 8933ddbdeba105cfceac8a4048cb0eb7 523 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 128 146 6.9E-8 T 06-07-2017 CAK77_RS13105 8933ddbdeba105cfceac8a4048cb0eb7 523 Pfam PF00890 FAD binding domain 14 381 1.2E-89 T 06-07-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK77_RS13105 8933ddbdeba105cfceac8a4048cb0eb7 523 Gene3D G3DSA:3.90.700.10 233 337 4.9E-30 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK77_RS13105 8933ddbdeba105cfceac8a4048cb0eb7 523 SUPERFAMILY SSF46977 410 512 4.06E-19 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK77_RS13105 8933ddbdeba105cfceac8a4048cb0eb7 523 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 14 36 7.1E-6 T 06-07-2017 CAK77_RS13105 8933ddbdeba105cfceac8a4048cb0eb7 523 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 359 366 7.1E-6 T 06-07-2017 CAK77_RS13105 8933ddbdeba105cfceac8a4048cb0eb7 523 Pfam PF02910 Fumarate reductase flavoprotein C-term 417 506 8.8E-9 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK77_RS13105 8933ddbdeba105cfceac8a4048cb0eb7 523 SUPERFAMILY SSF51905 340 401 1.33E-54 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS13105 8933ddbdeba105cfceac8a4048cb0eb7 523 SUPERFAMILY SSF51905 11 224 1.33E-54 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS14075 03c0dab89687cbe7cf46c81ff6ec67d3 177 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 11 177 32.729 T 06-07-2017 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|Reactome: R-HSA-74217 CAK77_RS14075 03c0dab89687cbe7cf46c81ff6ec67d3 177 Pfam PF00156 Phosphoribosyl transferase domain 41 155 4.2E-15 T 06-07-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 CAK77_RS14075 03c0dab89687cbe7cf46c81ff6ec67d3 177 Gene3D G3DSA:3.40.50.2020 9 174 7.8E-51 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like CAK77_RS14075 03c0dab89687cbe7cf46c81ff6ec67d3 177 SUPERFAMILY SSF53271 5 166 7.34E-38 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like CAK77_RS01845 31ac879b01605b81c705bc31d8be8ae7 295 SUPERFAMILY SSF51679 11 246 1.96E-57 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS01845 31ac879b01605b81c705bc31d8be8ae7 295 Pfam PF00296 Luciferase-like monooxygenase 2 256 5.7E-51 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS01845 31ac879b01605b81c705bc31d8be8ae7 295 TIGRFAM TIGR03619 F420_Rv2161c: probable F420-dependent oxidoreductase, Rv2161c family 22 267 2.0E-79 T 06-07-2017 IPR019921 Luciferase-like, F420-dependent oxidoreductase, Rv2161c, predicted CAK77_RS01845 31ac879b01605b81c705bc31d8be8ae7 295 Gene3D G3DSA:3.20.20.30 4 263 3.4E-63 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS17585 ffc59b6fc2482cb976bc1a9aa0fb8ec0 689 Gene3D G3DSA:1.10.150.80 617 684 4.1E-14 T 06-07-2017 IPR002121 HRDC domain GO:0003676|GO:0005622 CAK77_RS17585 ffc59b6fc2482cb976bc1a9aa0fb8ec0 689 SUPERFAMILY SSF52540 4 571 6.08E-126 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS17585 ffc59b6fc2482cb976bc1a9aa0fb8ec0 689 Gene3D G3DSA:3.40.50.300 8 280 6.0E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS17585 ffc59b6fc2482cb976bc1a9aa0fb8ec0 689 Pfam PF00580 UvrD/REP helicase N-terminal domain 136 275 3.8E-21 T 06-07-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 CAK77_RS17585 ffc59b6fc2482cb976bc1a9aa0fb8ec0 689 Pfam PF00580 UvrD/REP helicase N-terminal domain 10 128 9.5E-23 T 06-07-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 CAK77_RS17585 ffc59b6fc2482cb976bc1a9aa0fb8ec0 689 SMART SM00341 614 688 5.9E-17 T 06-07-2017 IPR002121 HRDC domain GO:0003676|GO:0005622 CAK77_RS17585 ffc59b6fc2482cb976bc1a9aa0fb8ec0 689 Pfam PF00570 HRDC domain 618 684 2.4E-19 T 06-07-2017 IPR002121 HRDC domain GO:0003676|GO:0005622 CAK77_RS17585 ffc59b6fc2482cb976bc1a9aa0fb8ec0 689 Gene3D G3DSA:3.40.50.300 285 399 8.2E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS17585 ffc59b6fc2482cb976bc1a9aa0fb8ec0 689 Gene3D G3DSA:3.40.50.300 484 571 8.2E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS17585 ffc59b6fc2482cb976bc1a9aa0fb8ec0 689 Pfam PF13361 UvrD-like helicase C-terminal domain 282 406 8.2E-17 T 06-07-2017 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CAK77_RS17585 ffc59b6fc2482cb976bc1a9aa0fb8ec0 689 Pfam PF13361 UvrD-like helicase C-terminal domain 438 551 5.6E-20 T 06-07-2017 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CAK77_RS17585 ffc59b6fc2482cb976bc1a9aa0fb8ec0 689 SUPERFAMILY SSF47819 608 686 4.14E-20 T 06-07-2017 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 CAK77_RS18165 1fae6875765c977f946f17c4baaf7c86 158 SMART SM00344 13 120 3.9E-34 T 06-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CAK77_RS18165 1fae6875765c977f946f17c4baaf7c86 158 Pfam PF01037 Lrp/AsnC ligand binding domain 86 149 1.2E-10 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CAK77_RS18165 1fae6875765c977f946f17c4baaf7c86 158 SUPERFAMILY SSF46785 13 72 8.05E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS18165 1fae6875765c977f946f17c4baaf7c86 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 29 40 2.7E-13 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAK77_RS18165 1fae6875765c977f946f17c4baaf7c86 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 13 29 2.7E-13 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAK77_RS18165 1fae6875765c977f946f17c4baaf7c86 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 40 59 2.7E-13 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAK77_RS18165 1fae6875765c977f946f17c4baaf7c86 158 SUPERFAMILY SSF54909 76 153 3.75E-11 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAK77_RS18165 1fae6875765c977f946f17c4baaf7c86 158 Gene3D G3DSA:3.30.70.920 66 146 7.6E-21 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CAK77_RS18165 1fae6875765c977f946f17c4baaf7c86 158 Gene3D G3DSA:1.10.10.10 12 64 2.2E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS18165 1fae6875765c977f946f17c4baaf7c86 158 Pfam PF13404 AsnC-type helix-turn-helix domain 13 54 1.3E-11 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAK77_RS12865 e1b640711d2b8c59cbb823d3048b26b7 902 Gene3D G3DSA:3.30.70.370 792 900 8.6E-65 T 06-07-2017 CAK77_RS12865 e1b640711d2b8c59cbb823d3048b26b7 902 Gene3D G3DSA:3.30.70.370 636 684 8.6E-65 T 06-07-2017 CAK77_RS12865 e1b640711d2b8c59cbb823d3048b26b7 902 SUPERFAMILY SSF53098 319 492 2.43E-33 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAK77_RS12865 e1b640711d2b8c59cbb823d3048b26b7 902 Gene3D G3DSA:3.30.420.10 318 514 6.1E-53 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAK77_RS12865 e1b640711d2b8c59cbb823d3048b26b7 902 Gene3D G3DSA:1.20.1060.10 517 635 1.7E-32 T 06-07-2017 CAK77_RS12865 e1b640711d2b8c59cbb823d3048b26b7 902 Pfam PF01612 3'-5' exonuclease 351 446 2.6E-4 T 06-07-2017 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 CAK77_RS12865 e1b640711d2b8c59cbb823d3048b26b7 902 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 184 277 5.0E-25 T 06-07-2017 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 CAK77_RS12865 e1b640711d2b8c59cbb823d3048b26b7 902 TIGRFAM TIGR00593 pola: DNA polymerase I 15 900 0.0 T 06-07-2017 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAK77_RS12865 e1b640711d2b8c59cbb823d3048b26b7 902 Gene3D G3DSA:1.10.150.20 198 257 5.6E-23 T 06-07-2017 CAK77_RS12865 e1b640711d2b8c59cbb823d3048b26b7 902 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 15 182 2.1E-54 T 06-07-2017 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 CAK77_RS12865 e1b640711d2b8c59cbb823d3048b26b7 902 SMART SM00474 314 491 1.6E-16 T 06-07-2017 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 CAK77_RS12865 e1b640711d2b8c59cbb823d3048b26b7 902 ProSitePatterns PS00447 DNA polymerase family A signature. 727 746 - T 06-07-2017 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAK77_RS12865 e1b640711d2b8c59cbb823d3048b26b7 902 SUPERFAMILY SSF88723 11 182 1.08E-52 T 06-07-2017 IPR029060 PIN domain-like CAK77_RS12865 e1b640711d2b8c59cbb823d3048b26b7 902 SMART SM00475 10 273 3.1E-137 T 06-07-2017 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 CAK77_RS12865 e1b640711d2b8c59cbb823d3048b26b7 902 Pfam PF00476 DNA polymerase family A 523 898 8.6E-142 T 06-07-2017 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAK77_RS12865 e1b640711d2b8c59cbb823d3048b26b7 902 Gene3D G3DSA:1.10.150.20 685 791 5.2E-31 T 06-07-2017 CAK77_RS12865 e1b640711d2b8c59cbb823d3048b26b7 902 PRINTS PR00868 DNA-polymerase family A (pol I) signature 818 834 3.2E-74 T 06-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAK77_RS12865 e1b640711d2b8c59cbb823d3048b26b7 902 PRINTS PR00868 DNA-polymerase family A (pol I) signature 727 752 3.2E-74 T 06-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAK77_RS12865 e1b640711d2b8c59cbb823d3048b26b7 902 PRINTS PR00868 DNA-polymerase family A (pol I) signature 764 775 3.2E-74 T 06-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAK77_RS12865 e1b640711d2b8c59cbb823d3048b26b7 902 PRINTS PR00868 DNA-polymerase family A (pol I) signature 703 716 3.2E-74 T 06-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAK77_RS12865 e1b640711d2b8c59cbb823d3048b26b7 902 PRINTS PR00868 DNA-polymerase family A (pol I) signature 786 797 3.2E-74 T 06-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAK77_RS12865 e1b640711d2b8c59cbb823d3048b26b7 902 PRINTS PR00868 DNA-polymerase family A (pol I) signature 650 665 3.2E-74 T 06-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAK77_RS12865 e1b640711d2b8c59cbb823d3048b26b7 902 PRINTS PR00868 DNA-polymerase family A (pol I) signature 627 649 3.2E-74 T 06-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAK77_RS12865 e1b640711d2b8c59cbb823d3048b26b7 902 PRINTS PR00868 DNA-polymerase family A (pol I) signature 673 696 3.2E-74 T 06-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAK77_RS12865 e1b640711d2b8c59cbb823d3048b26b7 902 PRINTS PR00868 DNA-polymerase family A (pol I) signature 848 861 3.2E-74 T 06-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAK77_RS12865 e1b640711d2b8c59cbb823d3048b26b7 902 SMART SM00482 658 865 8.4E-115 T 06-07-2017 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAK77_RS12865 e1b640711d2b8c59cbb823d3048b26b7 902 SMART SM00279 185 220 2.8E-13 T 06-07-2017 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 CAK77_RS12865 e1b640711d2b8c59cbb823d3048b26b7 902 SUPERFAMILY SSF47807 183 296 2.69E-28 T 06-07-2017 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 CAK77_RS12865 e1b640711d2b8c59cbb823d3048b26b7 902 SUPERFAMILY SSF56672 498 899 4.34E-138 T 06-07-2017 CAK77_RS12865 e1b640711d2b8c59cbb823d3048b26b7 902 Gene3D G3DSA:3.40.50.1010 14 197 1.1E-67 T 06-07-2017 IPR029060 PIN domain-like CAK77_RS16225 e69eb25d90544efbbfd722afb081dd6f 186 Pfam PF03729 Short repeat of unknown function (DUF308) 19 90 6.6E-12 T 06-07-2017 IPR005325 Protein of unknown function DUF308, membrane CAK77_RS16225 e69eb25d90544efbbfd722afb081dd6f 186 Pfam PF03729 Short repeat of unknown function (DUF308) 77 147 6.1E-9 T 06-07-2017 IPR005325 Protein of unknown function DUF308, membrane CAK77_RS16225 e69eb25d90544efbbfd722afb081dd6f 186 Pfam PF03729 Short repeat of unknown function (DUF308) 134 182 1.2E-7 T 06-07-2017 IPR005325 Protein of unknown function DUF308, membrane CAK77_RS24010 db892b82be5f8bbcb45c208ff2b51493 206 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 6 164 1.7E-19 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS24010 db892b82be5f8bbcb45c208ff2b51493 206 Gene3D G3DSA:1.10.1740.10 4 68 6.2E-21 T 06-07-2017 CAK77_RS24010 db892b82be5f8bbcb45c208ff2b51493 206 Gene3D G3DSA:1.10.10.10 107 167 3.7E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS24010 db892b82be5f8bbcb45c208ff2b51493 206 Pfam PF04542 Sigma-70 region 2 6 68 1.8E-14 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS24010 db892b82be5f8bbcb45c208ff2b51493 206 SUPERFAMILY SSF88659 101 165 1.16E-13 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS24010 db892b82be5f8bbcb45c208ff2b51493 206 SUPERFAMILY SSF88946 4 75 2.94E-18 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS24010 db892b82be5f8bbcb45c208ff2b51493 206 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 22 53 - T 06-07-2017 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS24010 db892b82be5f8bbcb45c208ff2b51493 206 Pfam PF08281 Sigma-70, region 4 109 160 1.5E-9 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS00590 53ba3057b3260c7558cb9b431d466a70 519 ProSitePatterns PS00123 Alkaline phosphatase active site. 128 136 - T 06-07-2017 IPR018299 Alkaline phosphatase, active site GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CAK77_RS00590 53ba3057b3260c7558cb9b431d466a70 519 PRINTS PR00113 Alkaline phosphatase signature 329 358 3.1E-34 T 06-07-2017 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CAK77_RS00590 53ba3057b3260c7558cb9b431d466a70 519 PRINTS PR00113 Alkaline phosphatase signature 68 88 3.1E-34 T 06-07-2017 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CAK77_RS00590 53ba3057b3260c7558cb9b431d466a70 519 PRINTS PR00113 Alkaline phosphatase signature 165 185 3.1E-34 T 06-07-2017 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CAK77_RS00590 53ba3057b3260c7558cb9b431d466a70 519 PRINTS PR00113 Alkaline phosphatase signature 228 238 3.1E-34 T 06-07-2017 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CAK77_RS00590 53ba3057b3260c7558cb9b431d466a70 519 PRINTS PR00113 Alkaline phosphatase signature 128 143 3.1E-34 T 06-07-2017 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CAK77_RS00590 53ba3057b3260c7558cb9b431d466a70 519 Gene3D G3DSA:3.40.720.10 57 479 9.5E-119 T 06-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CAK77_RS00590 53ba3057b3260c7558cb9b431d466a70 519 SMART SM00098 69 481 2.3E-124 T 06-07-2017 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CAK77_RS00590 53ba3057b3260c7558cb9b431d466a70 519 Pfam PF00245 Alkaline phosphatase 68 438 5.6E-95 T 06-07-2017 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CAK77_RS00590 53ba3057b3260c7558cb9b431d466a70 519 Pfam PF00245 Alkaline phosphatase 440 478 5.6E-7 T 06-07-2017 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CAK77_RS00590 53ba3057b3260c7558cb9b431d466a70 519 SUPERFAMILY SSF53649 61 479 1.57E-114 T 06-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CAK77_RS18630 0551a20450c01600aff35f5981607f31 155 SUPERFAMILY SSF55729 3 149 1.91E-31 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS18630 0551a20450c01600aff35f5981607f31 155 Gene3D G3DSA:3.40.630.30 1 149 9.1E-34 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS18630 0551a20450c01600aff35f5981607f31 155 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 12 146 1.9E-35 T 06-07-2017 IPR006464 Ribosomal-protein-alanine acetyltransferase GO:0006474|GO:0016407 CAK77_RS18630 0551a20450c01600aff35f5981607f31 155 Pfam PF00583 Acetyltransferase (GNAT) family 50 127 2.4E-16 T 06-07-2017 IPR000182 GNAT domain GO:0008080 CAK77_RS08470 9ac0762efafbc199b49bb82e7ba08c32 560 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 167 318 1.1E-37 T 06-07-2017 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAK77_RS08470 9ac0762efafbc199b49bb82e7ba08c32 560 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 422 552 2.8E-8 T 06-07-2017 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAK77_RS08470 9ac0762efafbc199b49bb82e7ba08c32 560 PRINTS PR00397 Sirohaem Fe-binding site signature 466 484 1.8E-8 T 06-07-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAK77_RS08470 9ac0762efafbc199b49bb82e7ba08c32 560 PRINTS PR00397 Sirohaem Fe-binding site signature 417 435 1.8E-8 T 06-07-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAK77_RS08470 9ac0762efafbc199b49bb82e7ba08c32 560 SUPERFAMILY SSF55124 16 166 4.09E-41 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAK77_RS08470 9ac0762efafbc199b49bb82e7ba08c32 560 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 466 482 - T 06-07-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAK77_RS08470 9ac0762efafbc199b49bb82e7ba08c32 560 SUPERFAMILY SSF55124 297 428 6.54E-17 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAK77_RS08470 9ac0762efafbc199b49bb82e7ba08c32 560 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 95 158 1.5E-13 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAK77_RS08470 9ac0762efafbc199b49bb82e7ba08c32 560 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 343 405 3.2E-12 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAK77_RS08470 9ac0762efafbc199b49bb82e7ba08c32 560 Gene3D G3DSA:3.90.480.10 95 164 7.0E-42 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAK77_RS08470 9ac0762efafbc199b49bb82e7ba08c32 560 Gene3D G3DSA:3.90.480.10 333 408 7.0E-42 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAK77_RS08470 9ac0762efafbc199b49bb82e7ba08c32 560 SUPERFAMILY SSF56014 167 326 2.09E-44 T 06-07-2017 CAK77_RS08470 9ac0762efafbc199b49bb82e7ba08c32 560 SUPERFAMILY SSF56014 414 558 1.06E-32 T 06-07-2017 CAK77_RS08470 9ac0762efafbc199b49bb82e7ba08c32 560 Gene3D G3DSA:3.30.413.10 167 316 1.1E-40 T 06-07-2017 CAK77_RS08470 9ac0762efafbc199b49bb82e7ba08c32 560 Gene3D G3DSA:3.30.413.10 418 559 1.0E-32 T 06-07-2017 CAK77_RS09655 be0bc6d7fde48f6f0931e3fcf9653192 167 SUPERFAMILY SSF53098 4 161 6.22E-5 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAK77_RS09655 be0bc6d7fde48f6f0931e3fcf9653192 167 Hamap MF_00977 3'-5' exoribonuclease. 1 164 42.643 T 06-07-2017 IPR030853 3-5 exoribonuclease, actinobacteria GO:0000287|GO:0008408 CAK77_RS09655 be0bc6d7fde48f6f0931e3fcf9653192 167 Pfam PF16473 3' exoribonuclease, RNase T-like 2 155 7.7E-18 T 06-07-2017 IPR033390 3'-5' exoribonuclease Rv2179c-like domain CAK77_RS10065 52a23f363617ab71f7321936a2a94e0e 495 SUPERFAMILY SSF51905 293 409 1.17E-52 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS10065 52a23f363617ab71f7321936a2a94e0e 495 SUPERFAMILY SSF51905 8 226 1.17E-52 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS10065 52a23f363617ab71f7321936a2a94e0e 495 Gene3D G3DSA:3.50.50.60 8 211 2.2E-57 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS10065 52a23f363617ab71f7321936a2a94e0e 495 Gene3D G3DSA:3.50.50.60 318 482 1.8E-17 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS10065 52a23f363617ab71f7321936a2a94e0e 495 Pfam PF00743 Flavin-binding monooxygenase-like 9 211 1.5E-19 T 06-07-2017 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 CAK77_RS16105 71ccee78e7d0352cbe8f2f8d22e728f5 523 Gene3D G3DSA:3.40.50.300 95 308 4.9E-77 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS16105 71ccee78e7d0352cbe8f2f8d22e728f5 523 Pfam PF02881 SRP54-type protein, helical bundle domain 5 82 4.0E-20 T 06-07-2017 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CAK77_RS16105 71ccee78e7d0352cbe8f2f8d22e728f5 523 Gene3D G3DSA:1.20.120.140 2 89 7.3E-32 T 06-07-2017 CAK77_RS16105 71ccee78e7d0352cbe8f2f8d22e728f5 523 SUPERFAMILY SSF47446 339 439 2.94E-32 T 06-07-2017 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 CAK77_RS16105 71ccee78e7d0352cbe8f2f8d22e728f5 523 Pfam PF02978 Signal peptide binding domain 339 436 3.6E-29 T 06-07-2017 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 CAK77_RS16105 71ccee78e7d0352cbe8f2f8d22e728f5 523 TIGRFAM TIGR00959 ffh: signal recognition particle protein 2 437 2.1E-174 T 06-07-2017 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 CAK77_RS16105 71ccee78e7d0352cbe8f2f8d22e728f5 523 SUPERFAMILY SSF52540 42 365 8.63E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS16105 71ccee78e7d0352cbe8f2f8d22e728f5 523 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 5 486 33.442 T 06-07-2017 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 CAK77_RS16105 71ccee78e7d0352cbe8f2f8d22e728f5 523 SMART SM00963 1 86 2.3E-32 T 06-07-2017 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CAK77_RS16105 71ccee78e7d0352cbe8f2f8d22e728f5 523 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 280 293 - T 06-07-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CAK77_RS16105 71ccee78e7d0352cbe8f2f8d22e728f5 523 Gene3D G3DSA:1.10.260.30 339 440 1.1E-35 T 06-07-2017 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 CAK77_RS16105 71ccee78e7d0352cbe8f2f8d22e728f5 523 Pfam PF00448 SRP54-type protein, GTPase domain 100 307 3.9E-69 T 06-07-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CAK77_RS16105 71ccee78e7d0352cbe8f2f8d22e728f5 523 SMART SM00962 100 307 2.6E-110 T 06-07-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CAK77_RS16105 71ccee78e7d0352cbe8f2f8d22e728f5 523 SMART SM00382 99 312 1.5E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS13955 38181aea8f848c65d7756b14e1984350 450 Gene3D G3DSA:3.40.50.300 25 165 1.8E-31 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS13955 38181aea8f848c65d7756b14e1984350 450 Gene3D G3DSA:1.10.8.60 166 244 1.0E-10 T 06-07-2017 CAK77_RS13955 38181aea8f848c65d7756b14e1984350 450 Pfam PF16193 AAA C-terminal domain 199 274 4.8E-27 T 06-07-2017 IPR032423 AAA ATPase, C-terminal domain CAK77_RS13955 38181aea8f848c65d7756b14e1984350 450 Gene3D G3DSA:1.10.3710.10 356 444 1.1E-25 T 06-07-2017 CAK77_RS13955 38181aea8f848c65d7756b14e1984350 450 Gene3D G3DSA:1.20.272.10 256 353 5.0E-45 T 06-07-2017 CAK77_RS13955 38181aea8f848c65d7756b14e1984350 450 SUPERFAMILY SSF52540 26 244 4.25E-38 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS13955 38181aea8f848c65d7756b14e1984350 450 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 65 160 9.4E-15 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 CAK77_RS13955 38181aea8f848c65d7756b14e1984350 450 Pfam PF12002 MgsA AAA+ ATPase C terminal 275 440 7.8E-66 T 06-07-2017 IPR021886 MgsA AAA+ ATPase C-terminal CAK77_RS13955 38181aea8f848c65d7756b14e1984350 450 SUPERFAMILY SSF48019 260 443 6.8E-71 T 06-07-2017 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 CAK77_RS13955 38181aea8f848c65d7756b14e1984350 450 SMART SM00382 61 177 9.2E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS17750 32d894313e045c13ae9f5fed98d58b27 235 Gene3D G3DSA:1.10.1740.10 45 121 1.6E-26 T 06-07-2017 CAK77_RS17750 32d894313e045c13ae9f5fed98d58b27 235 TIGRFAM TIGR02947 SigH_actino: RNA polymerase sigma-70 factor, TIGR02947 family 39 227 1.4E-107 T 06-07-2017 IPR014293 RNA polymerase sigma-70, actinobacteria GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS17750 32d894313e045c13ae9f5fed98d58b27 235 Gene3D G3DSA:1.10.10.10 158 217 2.9E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS17750 32d894313e045c13ae9f5fed98d58b27 235 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 74 105 - T 06-07-2017 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS17750 32d894313e045c13ae9f5fed98d58b27 235 SUPERFAMILY SSF88946 48 136 1.62E-23 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS17750 32d894313e045c13ae9f5fed98d58b27 235 Pfam PF08281 Sigma-70, region 4 159 211 6.6E-17 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS17750 32d894313e045c13ae9f5fed98d58b27 235 Pfam PF04542 Sigma-70 region 2 56 119 2.4E-17 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS17750 32d894313e045c13ae9f5fed98d58b27 235 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 57 214 7.3E-27 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS17750 32d894313e045c13ae9f5fed98d58b27 235 SUPERFAMILY SSF88659 159 216 4.67E-17 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS04315 d598573b7523dcaa3a41b21634f9b2d3 719 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 502 601 1.1E-20 T 06-07-2017 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 CAK77_RS04315 d598573b7523dcaa3a41b21634f9b2d3 719 Gene3D G3DSA:3.40.50.720 316 503 6.5E-58 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS04315 d598573b7523dcaa3a41b21634f9b2d3 719 SUPERFAMILY SSF52096 1 303 9.76E-56 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS04315 d598573b7523dcaa3a41b21634f9b2d3 719 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 321 499 1.4E-62 T 06-07-2017 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 CAK77_RS04315 d598573b7523dcaa3a41b21634f9b2d3 719 SUPERFAMILY SSF48179 501 645 5.7E-20 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAK77_RS04315 d598573b7523dcaa3a41b21634f9b2d3 719 Gene3D G3DSA:1.10.1040.10 504 601 2.1E-15 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAK77_RS04315 d598573b7523dcaa3a41b21634f9b2d3 719 Gene3D G3DSA:3.90.226.10 239 298 9.3E-51 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS04315 d598573b7523dcaa3a41b21634f9b2d3 719 Gene3D G3DSA:3.90.226.10 2 205 9.3E-51 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS04315 d598573b7523dcaa3a41b21634f9b2d3 719 SUPERFAMILY SSF51735 317 500 7.78E-59 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS04315 d598573b7523dcaa3a41b21634f9b2d3 719 Pfam PF00378 Enoyl-CoA hydratase/isomerase 13 205 4.4E-30 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAK77_RS04315 d598573b7523dcaa3a41b21634f9b2d3 719 SUPERFAMILY SSF48179 631 716 1.36E-11 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAK77_RS16390 a4100495f4eb80d746c2c93423e5c654 207 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 4.0E-13 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 CAK77_RS16390 a4100495f4eb80d746c2c93423e5c654 207 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 4.0E-13 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 CAK77_RS16390 a4100495f4eb80d746c2c93423e5c654 207 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 4.0E-13 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 CAK77_RS16390 a4100495f4eb80d746c2c93423e5c654 207 SMART SM00411 1 90 3.0E-38 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 CAK77_RS16390 a4100495f4eb80d746c2c93423e5c654 207 Gene3D G3DSA:4.10.520.10 1 91 1.9E-29 T 06-07-2017 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CAK77_RS16390 a4100495f4eb80d746c2c93423e5c654 207 SUPERFAMILY SSF47729 1 92 1.91E-27 T 06-07-2017 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CAK77_RS16390 a4100495f4eb80d746c2c93423e5c654 207 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 06-07-2017 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 CAK77_RS16390 a4100495f4eb80d746c2c93423e5c654 207 Pfam PF00216 Bacterial DNA-binding protein 1 89 2.0E-26 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 CAK77_RS01685 54ac3c0a275eaeb0aefa5b916e2de74f 54 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 1 54 4.6E-24 T 06-07-2017 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS01685 54ac3c0a275eaeb0aefa5b916e2de74f 54 SUPERFAMILY SSF57829 4 54 2.99E-17 T 06-07-2017 IPR011332 Zinc-binding ribosomal protein GO:0006412 CAK77_RS01685 54ac3c0a275eaeb0aefa5b916e2de74f 54 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 2 54 14.301 T 06-07-2017 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS01685 54ac3c0a275eaeb0aefa5b916e2de74f 54 ProSitePatterns PS00582 Ribosomal protein L33 signature. 22 41 - T 06-07-2017 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS01685 54ac3c0a275eaeb0aefa5b916e2de74f 54 Pfam PF00471 Ribosomal protein L33 9 54 8.2E-17 T 06-07-2017 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS16870 57e20e576ef57d4d367a04e5160bc500 170 Pfam PF04075 Domain of unknown function (DUF385) 60 167 1.6E-29 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CAK77_RS16870 57e20e576ef57d4d367a04e5160bc500 170 Gene3D G3DSA:2.30.110.10 63 127 2.5E-7 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS16870 57e20e576ef57d4d367a04e5160bc500 170 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 60 167 1.1E-26 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CAK77_RS16870 57e20e576ef57d4d367a04e5160bc500 170 SUPERFAMILY SSF50475 65 169 7.11E-9 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS19595 2cd0e033eb20e5c17111ea0ea3e22840 163 Pfam PF04461 Protein of unknown function (DUF520) 4 163 1.8E-61 T 06-07-2017 IPR007551 Protein of unknown function DUF520 CAK77_RS19595 2cd0e033eb20e5c17111ea0ea3e22840 163 Gene3D G3DSA:3.30.70.990 11 97 8.9E-30 T 06-07-2017 CAK77_RS19595 2cd0e033eb20e5c17111ea0ea3e22840 163 Hamap MF_00632 UPF0234 protein YajQ [yajQ]. 3 163 26.718 T 06-07-2017 IPR007551 Protein of unknown function DUF520 CAK77_RS19595 2cd0e033eb20e5c17111ea0ea3e22840 163 SUPERFAMILY SSF89963 91 163 1.7E-25 T 06-07-2017 IPR007551 Protein of unknown function DUF520 CAK77_RS19595 2cd0e033eb20e5c17111ea0ea3e22840 163 Gene3D G3DSA:3.30.70.860 98 163 2.5E-31 T 06-07-2017 CAK77_RS19595 2cd0e033eb20e5c17111ea0ea3e22840 163 SUPERFAMILY SSF89963 5 89 2.38E-26 T 06-07-2017 IPR007551 Protein of unknown function DUF520 CAK77_RS14150 3b4b7371684893af5c11688bbcd021c6 340 Pfam PF01680 SOR/SNZ family 53 258 1.4E-106 T 06-07-2017 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CAK77_RS14150 3b4b7371684893af5c11688bbcd021c6 340 Hamap MF_01824 Pyridoxal 5'-phosphate synthase subunit PdxS [pdxS]. 50 340 53.446 T 06-07-2017 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CAK77_RS14150 3b4b7371684893af5c11688bbcd021c6 340 Gene3D G3DSA:3.20.20.70 238 324 1.2E-47 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK77_RS14150 3b4b7371684893af5c11688bbcd021c6 340 Gene3D G3DSA:3.20.20.70 70 206 1.2E-47 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK77_RS14150 3b4b7371684893af5c11688bbcd021c6 340 SUPERFAMILY SSF51366 64 313 2.82E-60 T 06-07-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CAK77_RS14150 3b4b7371684893af5c11688bbcd021c6 340 TIGRFAM TIGR00343 TIGR00343: pyridoxal 5'-phosphate synthase, synthase subunit Pdx1 55 340 1.4E-144 T 06-07-2017 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CAK77_RS14150 3b4b7371684893af5c11688bbcd021c6 340 ProSitePatterns PS01235 PdxS/SNZ family signature. 251 269 - T 06-07-2017 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CAK77_RS14150 3b4b7371684893af5c11688bbcd021c6 340 PIRSF PIRSF029271 41 340 2.1E-150 T 06-07-2017 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CAK77_RS05395 258c077347a4a638bc7ccdad485b6a82 568 Pfam PF07287 Protein of unknown function (DUF1446) 8 333 1.7E-129 T 06-07-2017 IPR010839 Protein of unknown function DUF1446 CAK77_RS13980 7fefa87dfaf0b63921e07f14e7dfdbdc 887 Pfam PF14403 Circularly permuted ATP-grasp type 2 121 495 2.1E-125 T 06-07-2017 IPR025841 Circularly permuted ATP-grasp type 2 CAK77_RS13980 7fefa87dfaf0b63921e07f14e7dfdbdc 887 Pfam PF04168 A predicted alpha-helical domain with a conserved ER motif. 547 867 8.5E-68 T 06-07-2017 IPR007296 Domain of unknown function DUF403 CAK77_RS13980 7fefa87dfaf0b63921e07f14e7dfdbdc 887 SUPERFAMILY SSF56059 366 458 2.08E-7 T 06-07-2017 CAK77_RS13980 7fefa87dfaf0b63921e07f14e7dfdbdc 887 SUPERFAMILY SSF56059 112 259 2.08E-7 T 06-07-2017 CAK77_RS24355 9dd81839ccba11da660d557fc2bb0be8 314 Pfam PF13614 AAA domain 54 230 6.6E-58 T 06-07-2017 IPR025669 AAA domain CAK77_RS24355 9dd81839ccba11da660d557fc2bb0be8 314 SUPERFAMILY SSF52540 55 305 3.0E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS24355 9dd81839ccba11da660d557fc2bb0be8 314 Gene3D G3DSA:3.40.50.300 56 307 3.5E-71 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS00865 d139d18709b8dfe9ae46963f91624b9f 268 PIRSF PIRSF003073 11 261 1.8E-85 T 06-07-2017 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein CAK77_RS00865 d139d18709b8dfe9ae46963f91624b9f 268 Pfam PF01695 IstB-like ATP binding protein 71 242 2.7E-61 T 06-07-2017 IPR002611 IstB-like ATP-binding protein GO:0005524 CAK77_RS00865 d139d18709b8dfe9ae46963f91624b9f 268 Gene3D G3DSA:3.40.50.300 72 242 7.5E-24 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS00865 d139d18709b8dfe9ae46963f91624b9f 268 SMART SM00382 110 243 4.2E-8 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS00865 d139d18709b8dfe9ae46963f91624b9f 268 SUPERFAMILY SSF52540 79 240 6.97E-23 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS14265 d139d18709b8dfe9ae46963f91624b9f 268 PIRSF PIRSF003073 11 261 1.8E-85 T 06-07-2017 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein CAK77_RS14265 d139d18709b8dfe9ae46963f91624b9f 268 Pfam PF01695 IstB-like ATP binding protein 71 242 2.7E-61 T 06-07-2017 IPR002611 IstB-like ATP-binding protein GO:0005524 CAK77_RS14265 d139d18709b8dfe9ae46963f91624b9f 268 Gene3D G3DSA:3.40.50.300 72 242 7.5E-24 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS14265 d139d18709b8dfe9ae46963f91624b9f 268 SMART SM00382 110 243 4.2E-8 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS14265 d139d18709b8dfe9ae46963f91624b9f 268 SUPERFAMILY SSF52540 79 240 6.97E-23 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS12675 d139d18709b8dfe9ae46963f91624b9f 268 PIRSF PIRSF003073 11 261 1.8E-85 T 06-07-2017 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein CAK77_RS12675 d139d18709b8dfe9ae46963f91624b9f 268 Pfam PF01695 IstB-like ATP binding protein 71 242 2.7E-61 T 06-07-2017 IPR002611 IstB-like ATP-binding protein GO:0005524 CAK77_RS12675 d139d18709b8dfe9ae46963f91624b9f 268 Gene3D G3DSA:3.40.50.300 72 242 7.5E-24 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS12675 d139d18709b8dfe9ae46963f91624b9f 268 SMART SM00382 110 243 4.2E-8 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS12675 d139d18709b8dfe9ae46963f91624b9f 268 SUPERFAMILY SSF52540 79 240 6.97E-23 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS09710 403396e696610256456a7b842a3291f6 143 ProDom PD006745 MRAZ YABB DIVISION CELL 3D-STRUCTURE UNCHARACTERIZED BCR SIMILAR PROTEIN 1 128 2.0E-63 T 06-07-2017 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 CAK77_RS09710 403396e696610256456a7b842a3291f6 143 Hamap MF_01008 Transcriptional regulator MraZ [mraZ]. 1 143 48.872 T 06-07-2017 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 CAK77_RS09710 403396e696610256456a7b842a3291f6 143 Pfam PF02381 MraZ protein, putative antitoxin-like 73 137 8.9E-22 T 06-07-2017 IPR020603 MraZ domain CAK77_RS09710 403396e696610256456a7b842a3291f6 143 Pfam PF02381 MraZ protein, putative antitoxin-like 2 71 6.3E-21 T 06-07-2017 IPR020603 MraZ domain CAK77_RS09710 403396e696610256456a7b842a3291f6 143 TIGRFAM TIGR00242 TIGR00242: division/cell wall cluster transcriptional repressor MraZ 2 136 2.5E-33 T 06-07-2017 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 CAK77_RS09710 403396e696610256456a7b842a3291f6 143 SUPERFAMILY SSF89447 2 134 3.14E-43 T 06-07-2017 CAK77_RS09520 20206d110b50fb66ced8d3b87ba434dd 646 SUPERFAMILY SSF56235 2 231 5.23E-57 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAK77_RS09520 20206d110b50fb66ced8d3b87ba434dd 646 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 562 2.7E-140 T 06-07-2017 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 CAK77_RS09520 20206d110b50fb66ced8d3b87ba434dd 646 Gene3D G3DSA:3.60.20.10 2 233 1.2E-68 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAK77_RS09520 20206d110b50fb66ced8d3b87ba434dd 646 PIRSF PIRSF001589 1 642 4.1E-163 T 06-07-2017 CAK77_RS09520 20206d110b50fb66ced8d3b87ba434dd 646 Pfam PF00733 Asparagine synthase 251 625 2.0E-105 T 06-07-2017 IPR001962 Asparagine synthase GO:0004066|GO:0006529 CAK77_RS09520 20206d110b50fb66ced8d3b87ba434dd 646 Pfam PF13537 Glutamine amidotransferase domain 50 172 1.4E-38 T 06-07-2017 IPR017932 Glutamine amidotransferase type 2 domain CAK77_RS09520 20206d110b50fb66ced8d3b87ba434dd 646 SUPERFAMILY SSF52402 478 621 1.15E-81 T 06-07-2017 CAK77_RS09520 20206d110b50fb66ced8d3b87ba434dd 646 SUPERFAMILY SSF52402 246 391 1.15E-81 T 06-07-2017 CAK77_RS09520 20206d110b50fb66ced8d3b87ba434dd 646 Gene3D G3DSA:3.40.50.620 473 625 1.7E-93 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS09520 20206d110b50fb66ced8d3b87ba434dd 646 Gene3D G3DSA:3.40.50.620 235 387 1.7E-93 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS02000 cca106c3b187d1d5f33c94bebbb0aaba 552 Gene3D G3DSA:3.40.50.300 137 284 4.9E-16 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS02000 cca106c3b187d1d5f33c94bebbb0aaba 552 Pfam PF13538 UvrD-like helicase C-terminal domain 477 523 3.1E-14 T 06-07-2017 IPR027785 UvrD-like helicase C-terminal domain CAK77_RS02000 cca106c3b187d1d5f33c94bebbb0aaba 552 Gene3D G3DSA:3.40.50.300 368 414 9.5E-42 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS02000 cca106c3b187d1d5f33c94bebbb0aaba 552 Gene3D G3DSA:3.40.50.300 464 535 9.5E-42 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS02000 cca106c3b187d1d5f33c94bebbb0aaba 552 Gene3D G3DSA:3.40.50.300 285 336 9.5E-42 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS02000 cca106c3b187d1d5f33c94bebbb0aaba 552 TIGRFAM TIGR01447 recD: exodeoxyribonuclease V, alpha subunit 9 547 1.3E-163 T 06-07-2017 IPR006344 RecBCD enzyme subunit RecD GO:0004386|GO:0006302|GO:0006310|GO:0008854|GO:0009338 CAK77_RS02000 cca106c3b187d1d5f33c94bebbb0aaba 552 SUPERFAMILY SSF52540 137 528 2.67E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS02000 cca106c3b187d1d5f33c94bebbb0aaba 552 Hamap MF_01487 RecBCD enzyme subunit RecD [recD]. 11 545 44.818 T 06-07-2017 IPR006344 RecBCD enzyme subunit RecD GO:0004386|GO:0006302|GO:0006310|GO:0008854|GO:0009338 CAK77_RS02000 cca106c3b187d1d5f33c94bebbb0aaba 552 Pfam PF13604 AAA domain 137 345 9.4E-40 T 06-07-2017 CAK77_RS22840 9df83caab60aa5b5c755a2101d2ac20c 364 SUPERFAMILY SSF56112 21 359 1.79E-50 T 06-07-2017 IPR011009 Protein kinase-like domain CAK77_RS22840 9df83caab60aa5b5c755a2101d2ac20c 364 Gene3D G3DSA:3.30.200.20 21 110 8.7E-4 T 06-07-2017 CAK77_RS22840 9df83caab60aa5b5c755a2101d2ac20c 364 Gene3D G3DSA:3.90.1200.10 123 268 2.0E-30 T 06-07-2017 CAK77_RS22840 9df83caab60aa5b5c755a2101d2ac20c 364 Pfam PF01636 Phosphotransferase enzyme family 42 268 1.0E-43 T 06-07-2017 IPR002575 Aminoglycoside phosphotransferase CAK77_RS22840 9df83caab60aa5b5c755a2101d2ac20c 364 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 218 230 - T 06-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CAK77_RS11365 e415de69914e8b557adbf5561cebf8be 827 Gene3D G3DSA:2.40.50.140 46 164 9.9E-37 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS11365 e415de69914e8b557adbf5561cebf8be 827 Pfam PF03147 Ferredoxin-fold anticodon binding domain 733 826 3.6E-22 T 06-07-2017 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 CAK77_RS11365 e415de69914e8b557adbf5561cebf8be 827 SUPERFAMILY SSF56037 210 401 1.88E-59 T 06-07-2017 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 Reactome: R-HSA-379716 CAK77_RS11365 e415de69914e8b557adbf5561cebf8be 827 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 824 4.6E-163 T 06-07-2017 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 CAK77_RS11365 e415de69914e8b557adbf5561cebf8be 827 SUPERFAMILY SSF46955 414 484 3.11E-14 T 06-07-2017 IPR009061 Putative DNA-binding domain CAK77_RS11365 e415de69914e8b557adbf5561cebf8be 827 SMART SM00874 412 480 4.0E-18 T 06-07-2017 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 CAK77_RS11365 e415de69914e8b557adbf5561cebf8be 827 SMART SM00896 733 826 1.7E-32 T 06-07-2017 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 CAK77_RS11365 e415de69914e8b557adbf5561cebf8be 827 Gene3D G3DSA:3.30.70.380 735 826 2.2E-26 T 06-07-2017 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 CAK77_RS11365 e415de69914e8b557adbf5561cebf8be 827 Gene3D G3DSA:3.30.930.10 495 722 2.2E-59 T 06-07-2017 CAK77_RS11365 e415de69914e8b557adbf5561cebf8be 827 Pfam PF03483 B3/4 domain 224 395 2.9E-55 T 06-07-2017 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 CAK77_RS11365 e415de69914e8b557adbf5561cebf8be 827 Pfam PF01588 Putative tRNA binding domain 50 151 8.5E-19 T 06-07-2017 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 CAK77_RS11365 e415de69914e8b557adbf5561cebf8be 827 SUPERFAMILY SSF55681 476 592 2.34E-36 T 06-07-2017 CAK77_RS11365 e415de69914e8b557adbf5561cebf8be 827 SUPERFAMILY SSF55681 622 722 2.34E-36 T 06-07-2017 CAK77_RS11365 e415de69914e8b557adbf5561cebf8be 827 Pfam PF03484 tRNA synthetase B5 domain 415 479 7.7E-13 T 06-07-2017 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 CAK77_RS11365 e415de69914e8b557adbf5561cebf8be 827 Gene3D G3DSA:3.30.56.20 412 484 1.9E-19 T 06-07-2017 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 CAK77_RS11365 e415de69914e8b557adbf5561cebf8be 827 Gene3D G3DSA:3.50.40.10 212 404 1.1E-66 T 06-07-2017 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 Reactome: R-HSA-379716 CAK77_RS11365 e415de69914e8b557adbf5561cebf8be 827 SMART SM00873 222 395 3.8E-69 T 06-07-2017 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 CAK77_RS11365 e415de69914e8b557adbf5561cebf8be 827 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 820 37.82 T 06-07-2017 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 CAK77_RS11365 e415de69914e8b557adbf5561cebf8be 827 Gene3D G3DSA:3.30.56.10 165 194 1.1E-13 T 06-07-2017 CAK77_RS11365 e415de69914e8b557adbf5561cebf8be 827 Gene3D G3DSA:3.30.56.10 1 43 1.1E-13 T 06-07-2017 CAK77_RS11365 e415de69914e8b557adbf5561cebf8be 827 SUPERFAMILY SSF54991 730 826 7.32E-23 T 06-07-2017 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 CAK77_RS11365 e415de69914e8b557adbf5561cebf8be 827 SUPERFAMILY SSF50249 46 200 2.34E-32 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS20235 0ae375d10d673275649c7866ef315d8b 496 SUPERFAMILY SSF51905 237 468 2.07E-15 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS20235 0ae375d10d673275649c7866ef315d8b 496 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 9 31 7.9E-8 T 06-07-2017 CAK77_RS20235 0ae375d10d673275649c7866ef315d8b 496 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 175 200 7.9E-8 T 06-07-2017 CAK77_RS20235 0ae375d10d673275649c7866ef315d8b 496 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 11 206 1.0E-12 T 06-07-2017 CAK77_RS20235 0ae375d10d673275649c7866ef315d8b 496 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 175 193 4.2E-7 T 06-07-2017 CAK77_RS20235 0ae375d10d673275649c7866ef315d8b 496 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 10 29 4.2E-7 T 06-07-2017 CAK77_RS20235 0ae375d10d673275649c7866ef315d8b 496 SUPERFAMILY SSF51905 7 225 1.59E-48 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS20235 0ae375d10d673275649c7866ef315d8b 496 Gene3D G3DSA:3.50.50.60 8 207 2.2E-53 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS20235 0ae375d10d673275649c7866ef315d8b 496 Gene3D G3DSA:3.50.50.60 320 475 3.2E-8 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS21610 9914988e5329bacd8a16d0b4f2d8cd06 446 PIRSF PIRSF000124 1 438 2.9E-120 T 06-07-2017 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CAK77_RS21610 9914988e5329bacd8a16d0b4f2d8cd06 446 PIRSF PIRSF500134 1 441 4.1E-159 T 06-07-2017 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00500+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346 CAK77_RS21610 9914988e5329bacd8a16d0b4f2d8cd06 446 Gene3D G3DSA:3.40.50.720 235 440 2.7E-67 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS21610 9914988e5329bacd8a16d0b4f2d8cd06 446 SUPERFAMILY SSF52413 311 434 1.7E-33 T 06-07-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CAK77_RS21610 9914988e5329bacd8a16d0b4f2d8cd06 446 Gene3D G3DSA:3.40.50.720 1 206 2.9E-71 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS21610 9914988e5329bacd8a16d0b4f2d8cd06 446 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 179 3.6E-62 T 06-07-2017 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CAK77_RS21610 9914988e5329bacd8a16d0b4f2d8cd06 446 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 419 1.4E-136 T 06-07-2017 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CAK77_RS21610 9914988e5329bacd8a16d0b4f2d8cd06 446 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 204 298 2.3E-31 T 06-07-2017 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CAK77_RS21610 9914988e5329bacd8a16d0b4f2d8cd06 446 SMART SM00984 322 423 7.4E-44 T 06-07-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CAK77_RS21610 9914988e5329bacd8a16d0b4f2d8cd06 446 SUPERFAMILY SSF48179 204 303 8.33E-28 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAK77_RS21610 9914988e5329bacd8a16d0b4f2d8cd06 446 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 322 422 1.8E-27 T 06-07-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CAK77_RS21610 9914988e5329bacd8a16d0b4f2d8cd06 446 Gene3D G3DSA:1.20.5.100 207 234 1.5E-16 T 06-07-2017 CAK77_RS21610 9914988e5329bacd8a16d0b4f2d8cd06 446 SUPERFAMILY SSF51735 1 196 8.86E-49 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS24335 316791dc905b2a8eb27d1de6082bac97 213 Gene3D G3DSA:1.10.357.10 74 213 1.5E-19 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS24335 316791dc905b2a8eb27d1de6082bac97 213 SUPERFAMILY SSF48498 108 212 2.4E-13 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS24335 316791dc905b2a8eb27d1de6082bac97 213 SUPERFAMILY SSF46689 14 90 3.82E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS24335 316791dc905b2a8eb27d1de6082bac97 213 Pfam PF00440 Bacterial regulatory proteins, tetR family 28 73 2.9E-15 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS24335 316791dc905b2a8eb27d1de6082bac97 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 40 7.1E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS24335 316791dc905b2a8eb27d1de6082bac97 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 48 71 7.1E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS24335 316791dc905b2a8eb27d1de6082bac97 213 Gene3D G3DSA:1.10.10.60 14 73 1.3E-19 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS21970 4ba7d73ef6bbce304391902e9466aece 227 SUPERFAMILY SSF53474 4 201 9.78E-27 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS21970 4ba7d73ef6bbce304391902e9466aece 227 Gene3D G3DSA:3.40.50.1820 3 203 4.3E-46 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS21970 4ba7d73ef6bbce304391902e9466aece 227 SMART SM01110 10 201 1.6E-59 T 06-07-2017 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 CAK77_RS21970 4ba7d73ef6bbce304391902e9466aece 227 Pfam PF01083 Cutinase 11 201 9.7E-40 T 06-07-2017 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 CAK77_RS20060 88538226e88ba6a10d8eb586db49522e 83 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 29 76 4.1E-19 T 06-07-2017 IPR010093 SinI-like, DNA-binding domain GO:0003677 CAK77_RS20060 88538226e88ba6a10d8eb586db49522e 83 Gene3D G3DSA:1.10.10.10 29 77 7.1E-4 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS20060 88538226e88ba6a10d8eb586db49522e 83 SUPERFAMILY SSF46955 29 78 8.42E-6 T 06-07-2017 IPR009061 Putative DNA-binding domain CAK77_RS20060 88538226e88ba6a10d8eb586db49522e 83 Pfam PF12728 Helix-turn-helix domain 29 77 5.8E-14 T 06-07-2017 CAK77_RS00220 bc4b47b45a80dc9c02f3d0779224c03d 512 SUPERFAMILY SSF49503 73 208 2.94E-35 T 06-07-2017 IPR008972 Cupredoxin CAK77_RS00220 bc4b47b45a80dc9c02f3d0779224c03d 512 Gene3D G3DSA:2.60.40.420 65 184 8.2E-34 T 06-07-2017 IPR008972 Cupredoxin CAK77_RS00220 bc4b47b45a80dc9c02f3d0779224c03d 512 ProSitePatterns PS00080 Multicopper oxidases signature 2. 493 504 - T 06-07-2017 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 CAK77_RS00220 bc4b47b45a80dc9c02f3d0779224c03d 512 SUPERFAMILY SSF49503 186 331 2.89E-22 T 06-07-2017 IPR008972 Cupredoxin CAK77_RS00220 bc4b47b45a80dc9c02f3d0779224c03d 512 Gene3D G3DSA:2.60.40.420 383 510 1.2E-41 T 06-07-2017 IPR008972 Cupredoxin CAK77_RS00220 bc4b47b45a80dc9c02f3d0779224c03d 512 Gene3D G3DSA:2.60.40.420 186 382 1.6E-35 T 06-07-2017 IPR008972 Cupredoxin CAK77_RS00220 bc4b47b45a80dc9c02f3d0779224c03d 512 Pfam PF00394 Multicopper oxidase 256 331 1.0E-15 T 06-07-2017 IPR001117 Multicopper oxidase, type 1 GO:0016491|GO:0055114 CAK77_RS00220 bc4b47b45a80dc9c02f3d0779224c03d 512 Pfam PF07731 Multicopper oxidase 407 509 3.3E-26 T 06-07-2017 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 CAK77_RS00220 bc4b47b45a80dc9c02f3d0779224c03d 512 Pfam PF07732 Multicopper oxidase 79 182 3.2E-32 T 06-07-2017 IPR011707 Multicopper oxidase, type 3 GO:0005507 CAK77_RS00220 bc4b47b45a80dc9c02f3d0779224c03d 512 SUPERFAMILY SSF49503 398 508 3.02E-34 T 06-07-2017 IPR008972 Cupredoxin CAK77_RS14805 414fe4bf443e84b1e785604fdfbdb82c 517 Gene3D G3DSA:3.40.50.1820 214 341 1.3E-37 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS14805 414fe4bf443e84b1e785604fdfbdb82c 517 Gene3D G3DSA:3.40.50.1820 86 170 1.3E-37 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS14805 414fe4bf443e84b1e785604fdfbdb82c 517 Gene3D G3DSA:3.40.50.1820 384 493 1.3E-37 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS14805 414fe4bf443e84b1e785604fdfbdb82c 517 SUPERFAMILY SSF53474 342 488 1.36E-20 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS14805 414fe4bf443e84b1e785604fdfbdb82c 517 SUPERFAMILY SSF53474 118 171 1.36E-20 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS14805 414fe4bf443e84b1e785604fdfbdb82c 517 SUPERFAMILY SSF53474 216 270 1.36E-20 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS14805 414fe4bf443e84b1e785604fdfbdb82c 517 Pfam PF08386 TAP-like protein 413 515 7.4E-17 T 06-07-2017 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal CAK77_RS22670 c8a5e64f78a7d8b93e89c414ac087d41 133 SUPERFAMILY SSF54593 1 128 9.2E-21 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK77_RS22670 c8a5e64f78a7d8b93e89c414ac087d41 133 Gene3D G3DSA:3.10.180.10 2 129 1.0E-25 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK77_RS19030 6d57341e4657180d43522045192e39dc 138 Gene3D G3DSA:3.90.1170.10 23 136 1.6E-51 T 06-07-2017 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 CAK77_RS19030 6d57341e4657180d43522045192e39dc 138 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 127 1.1E-54 T 06-07-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS19030 6d57341e4657180d43522045192e39dc 138 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 37.668 T 06-07-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS19030 6d57341e4657180d43522045192e39dc 138 SUPERFAMILY SSF54686 1 135 4.19E-55 T 06-07-2017 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 CAK77_RS19030 6d57341e4657180d43522045192e39dc 138 PRINTS PR00060 Ribosomal protein L16 signature 58 87 1.9E-38 T 06-07-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS19030 6d57341e4657180d43522045192e39dc 138 PRINTS PR00060 Ribosomal protein L16 signature 24 36 1.9E-38 T 06-07-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS19030 6d57341e4657180d43522045192e39dc 138 PRINTS PR00060 Ribosomal protein L16 signature 42 53 1.9E-38 T 06-07-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS19030 6d57341e4657180d43522045192e39dc 138 PRINTS PR00060 Ribosomal protein L16 signature 88 117 1.9E-38 T 06-07-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS19030 6d57341e4657180d43522045192e39dc 138 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 06-07-2017 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS19030 6d57341e4657180d43522045192e39dc 138 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 06-07-2017 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS19030 6d57341e4657180d43522045192e39dc 138 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 1.2E-46 T 06-07-2017 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 CAK77_RS23610 f2db5f3c7e630d057601976d28625932 274 Pfam PF00722 Glycosyl hydrolases family 16 93 271 2.6E-17 T 06-07-2017 IPR000757 Glycoside hydrolase family 16 GO:0004553|GO:0005975 CAK77_RS23610 f2db5f3c7e630d057601976d28625932 274 SUPERFAMILY SSF49899 36 274 4.62E-43 T 06-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain CAK77_RS23610 f2db5f3c7e630d057601976d28625932 274 Gene3D G3DSA:2.60.120.200 26 274 5.4E-47 T 06-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain CAK77_RS21220 eab181b1692c6a8128c917f8fff1aa28 352 SUPERFAMILY SSF51679 11 341 8.92E-73 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS21220 eab181b1692c6a8128c917f8fff1aa28 352 Pfam PF00296 Luciferase-like monooxygenase 28 266 1.9E-31 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS21220 eab181b1692c6a8128c917f8fff1aa28 352 Gene3D G3DSA:3.20.20.30 11 341 3.9E-89 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS18385 8b410ef291f327d7199427861c207433 109 Pfam PF11222 Protein of unknown function (DUF3017) 29 102 1.3E-21 T 06-07-2017 IPR021385 Protein of unknown function DUF3017 CAK77_RS21165 e2e1a2b6d289231cca8e411cdb660975 327 Gene3D G3DSA:3.40.190.10 89 173 6.3E-29 T 06-07-2017 CAK77_RS21165 e2e1a2b6d289231cca8e411cdb660975 327 Gene3D G3DSA:3.40.190.10 275 311 6.3E-29 T 06-07-2017 CAK77_RS21165 e2e1a2b6d289231cca8e411cdb660975 327 SMART SM00062 92 314 1.9E-65 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAK77_RS21165 e2e1a2b6d289231cca8e411cdb660975 327 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 93 312 8.4E-50 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAK77_RS21165 e2e1a2b6d289231cca8e411cdb660975 327 Gene3D G3DSA:3.40.190.10 174 274 7.5E-18 T 06-07-2017 CAK77_RS21165 e2e1a2b6d289231cca8e411cdb660975 327 SUPERFAMILY SSF53850 80 311 2.0E-52 T 06-07-2017 CAK77_RS17755 5889ac8f9dd86757e73076ea0af3907c 168 SUPERFAMILY SSF55826 10 165 3.14E-35 T 06-07-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CAK77_RS17755 5889ac8f9dd86757e73076ea0af3907c 168 PIRSF PIRSF006181 5 168 3.3E-43 T 06-07-2017 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC CAK77_RS17755 5889ac8f9dd86757e73076ea0af3907c 168 Pfam PF04073 Aminoacyl-tRNA editing domain 47 157 2.9E-22 T 06-07-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CAK77_RS17755 5889ac8f9dd86757e73076ea0af3907c 168 Gene3D G3DSA:3.90.960.10 7 166 1.7E-52 T 06-07-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CAK77_RS17070 db6c1067f0d6f2803b2f94afc614e9e9 330 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 224 308 4.0E-17 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CAK77_RS17070 db6c1067f0d6f2803b2f94afc614e9e9 330 SUPERFAMILY SSF90002 225 308 1.7E-11 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CAK77_RS17070 db6c1067f0d6f2803b2f94afc614e9e9 330 Gene3D G3DSA:3.30.1220.10 211 309 1.5E-13 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CAK77_RS17070 db6c1067f0d6f2803b2f94afc614e9e9 330 Gene3D G3DSA:3.40.50.300 2 192 1.9E-54 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS17070 db6c1067f0d6f2803b2f94afc614e9e9 330 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 3 178 1.8E-44 T 06-07-2017 IPR003495 CobW/HypB/UreG, nucleotide-binding domain CAK77_RS17070 db6c1067f0d6f2803b2f94afc614e9e9 330 SUPERFAMILY SSF52540 2 179 4.07E-32 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS17070 db6c1067f0d6f2803b2f94afc614e9e9 330 SMART SM00833 223 310 2.1E-12 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CAK77_RS14410 f30d0d92e52def013ab0a9de03cc1c31 888 Pfam PF01568 Molydopterin dinucleotide binding domain 775 879 2.0E-23 T 06-07-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CAK77_RS14410 f30d0d92e52def013ab0a9de03cc1c31 888 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 209 260 3.8E-19 T 06-07-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS14410 f30d0d92e52def013ab0a9de03cc1c31 888 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 140 151 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CAK77_RS14410 f30d0d92e52def013ab0a9de03cc1c31 888 SMART SM00926 208 262 2.7E-19 T 06-07-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS14410 f30d0d92e52def013ab0a9de03cc1c31 888 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 2 76 2.5E-17 T 06-07-2017 CAK77_RS14410 f30d0d92e52def013ab0a9de03cc1c31 888 SUPERFAMILY SSF53706 208 712 5.37E-182 T 06-07-2017 CAK77_RS14410 f30d0d92e52def013ab0a9de03cc1c31 888 Gene3D G3DSA:3.40.50.740 265 338 9.7E-74 T 06-07-2017 CAK77_RS14410 f30d0d92e52def013ab0a9de03cc1c31 888 Gene3D G3DSA:3.40.50.740 520 723 9.7E-74 T 06-07-2017 CAK77_RS14410 f30d0d92e52def013ab0a9de03cc1c31 888 Gene3D G3DSA:2.40.40.20 727 886 4.6E-33 T 06-07-2017 CAK77_RS14410 f30d0d92e52def013ab0a9de03cc1c31 888 Gene3D G3DSA:2.20.25.90 216 261 2.9E-22 T 06-07-2017 CAK77_RS14410 f30d0d92e52def013ab0a9de03cc1c31 888 TIGRFAM TIGR01591 Fdh-alpha: formate dehydrogenase, alpha subunit 213 883 4.6E-225 T 06-07-2017 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.2.1.2|KEGG: 00680+1.2.1.2|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696 CAK77_RS14410 f30d0d92e52def013ab0a9de03cc1c31 888 Gene3D G3DSA:3.40.228.10 340 519 1.3E-60 T 06-07-2017 CAK77_RS14410 f30d0d92e52def013ab0a9de03cc1c31 888 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 183 194 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CAK77_RS14410 f30d0d92e52def013ab0a9de03cc1c31 888 Gene3D G3DSA:3.30.70.20 190 215 8.3E-5 T 06-07-2017 CAK77_RS14410 f30d0d92e52def013ab0a9de03cc1c31 888 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 31 48 - T 06-07-2017 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS14410 f30d0d92e52def013ab0a9de03cc1c31 888 SUPERFAMILY SSF54292 1 115 1.23E-24 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK77_RS14410 f30d0d92e52def013ab0a9de03cc1c31 888 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 213 230 - T 06-07-2017 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 KEGG: 00910+1.7.99.4 CAK77_RS14410 f30d0d92e52def013ab0a9de03cc1c31 888 SUPERFAMILY SSF54862 124 200 1.15E-22 T 06-07-2017 CAK77_RS14410 f30d0d92e52def013ab0a9de03cc1c31 888 Pfam PF13187 4Fe-4S dicluster domain 139 197 7.9E-7 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CAK77_RS14410 f30d0d92e52def013ab0a9de03cc1c31 888 Pfam PF00384 Molybdopterin oxidoreductase 265 684 3.0E-71 T 06-07-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS14410 f30d0d92e52def013ab0a9de03cc1c31 888 Gene3D G3DSA:3.10.20.30 2 60 1.5E-8 T 06-07-2017 IPR012675 Beta-grasp domain CAK77_RS14410 f30d0d92e52def013ab0a9de03cc1c31 888 Gene3D G3DSA:3.30.70.20 129 189 7.5E-14 T 06-07-2017 CAK77_RS14410 f30d0d92e52def013ab0a9de03cc1c31 888 SUPERFAMILY SSF50692 729 886 1.79E-32 T 06-07-2017 IPR009010 Aspartate decarboxylase-like domain CAK77_RS14410 f30d0d92e52def013ab0a9de03cc1c31 888 PIRSF PIRSF036643 1 888 1.0E-299 T 06-07-2017 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.2.1.2|KEGG: 00680+1.2.1.2|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696 CAK77_RS02515 1431fddc911fad22cd8ec9e61123fbb0 980 SUPERFAMILY SSF82866 742 951 2.88E-27 T 06-07-2017 CAK77_RS02515 1431fddc911fad22cd8ec9e61123fbb0 980 Pfam PF03176 MMPL family 627 953 1.3E-59 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 CAK77_RS02515 1431fddc911fad22cd8ec9e61123fbb0 980 Pfam PF03176 MMPL family 74 403 1.2E-84 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 CAK77_RS02515 1431fddc911fad22cd8ec9e61123fbb0 980 SUPERFAMILY SSF82866 175 373 3.01E-28 T 06-07-2017 CAK77_RS02515 1431fddc911fad22cd8ec9e61123fbb0 980 Gene3D G3DSA:1.20.1640.10 761 953 1.2E-20 T 06-07-2017 CAK77_RS02515 1431fddc911fad22cd8ec9e61123fbb0 980 Gene3D G3DSA:1.20.1640.10 170 380 8.0E-31 T 06-07-2017 CAK77_RS15770 80a0b10fe125d95d156baaacb07bc1f5 391 Pfam PF04551 GcpE protein 24 364 1.2E-129 T 06-07-2017 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 CAK77_RS15770 80a0b10fe125d95d156baaacb07bc1f5 391 Gene3D G3DSA:3.20.20.70 52 185 6.2E-6 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK77_RS15770 80a0b10fe125d95d156baaacb07bc1f5 391 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 19 370 32.966 T 06-07-2017 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 CAK77_RS15770 80a0b10fe125d95d156baaacb07bc1f5 391 PIRSF PIRSF004640 15 375 4.1E-142 T 06-07-2017 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 CAK77_RS15770 80a0b10fe125d95d156baaacb07bc1f5 391 SUPERFAMILY SSF56014 279 361 7.85E-11 T 06-07-2017 CAK77_RS15770 80a0b10fe125d95d156baaacb07bc1f5 391 SUPERFAMILY SSF51717 25 221 6.83E-10 T 06-07-2017 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAK77_RS15770 80a0b10fe125d95d156baaacb07bc1f5 391 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 21 363 8.0E-125 T 06-07-2017 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 CAK77_RS17505 b248b8f46293b3b6b55ee4ea8a9da818 109 SUPERFAMILY SSF51182 35 103 3.47E-11 T 06-07-2017 IPR011051 RmlC-like cupin domain CAK77_RS17505 b248b8f46293b3b6b55ee4ea8a9da818 109 Pfam PF07883 Cupin domain 41 101 7.2E-7 T 06-07-2017 IPR013096 Cupin 2, conserved barrel CAK77_RS17505 b248b8f46293b3b6b55ee4ea8a9da818 109 Gene3D G3DSA:2.60.120.10 23 106 1.0E-14 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK77_RS05660 6eecdddaf72d451137f9f4998792e30c 216 Pfam PF01386 Ribosomal L25p family 12 98 5.1E-23 T 06-07-2017 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 CAK77_RS05660 6eecdddaf72d451137f9f4998792e30c 216 Gene3D G3DSA:2.40.240.10 11 100 1.2E-27 T 06-07-2017 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CAK77_RS05660 6eecdddaf72d451137f9f4998792e30c 216 Gene3D G3DSA:2.170.120.20 103 189 5.9E-22 T 06-07-2017 IPR020057 Ribosomal protein L25, beta domain CAK77_RS05660 6eecdddaf72d451137f9f4998792e30c 216 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 10 186 25.016 T 06-07-2017 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 CAK77_RS05660 6eecdddaf72d451137f9f4998792e30c 216 SUPERFAMILY SSF50715 11 189 1.12E-47 T 06-07-2017 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CAK77_RS05660 6eecdddaf72d451137f9f4998792e30c 216 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 106 184 5.0E-20 T 06-07-2017 IPR020057 Ribosomal protein L25, beta domain CAK77_RS05660 6eecdddaf72d451137f9f4998792e30c 216 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 11 99 9.0E-34 T 06-07-2017 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 CAK77_RS05660 6eecdddaf72d451137f9f4998792e30c 216 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 12 183 1.2E-53 T 06-07-2017 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 CAK77_RS24185 f870c64f381fae2025e9c6bbce708305 324 Gene3D G3DSA:3.40.50.970 2 195 6.1E-77 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK77_RS24185 f870c64f381fae2025e9c6bbce708305 324 Gene3D G3DSA:3.40.50.920 196 318 6.5E-43 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CAK77_RS24185 f870c64f381fae2025e9c6bbce708305 324 Pfam PF02780 Transketolase, C-terminal domain 193 314 1.3E-38 T 06-07-2017 IPR033248 Transketolase, C-terminal domain CAK77_RS24185 f870c64f381fae2025e9c6bbce708305 324 SMART SM00861 4 179 1.5E-68 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain CAK77_RS24185 f870c64f381fae2025e9c6bbce708305 324 Pfam PF02779 Transketolase, pyrimidine binding domain 4 177 2.0E-45 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain CAK77_RS24185 f870c64f381fae2025e9c6bbce708305 324 SUPERFAMILY SSF52518 1 202 8.57E-68 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK77_RS24185 f870c64f381fae2025e9c6bbce708305 324 SUPERFAMILY SSF52922 189 321 7.46E-38 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CAK77_RS07385 36fa199965d65c8be334cb5c4ad9dd0a 690 SUPERFAMILY SSF51445 220 581 1.1E-79 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily CAK77_RS07385 36fa199965d65c8be334cb5c4ad9dd0a 690 Hamap MF_02124 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase [glgE]. 1 677 44.854 T 06-07-2017 IPR026585 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase GO:0016757 KEGG: 00500+2.4.99.16 CAK77_RS07385 36fa199965d65c8be334cb5c4ad9dd0a 690 Gene3D G3DSA:2.60.40.1180 586 668 2.5E-6 T 06-07-2017 IPR013780 Glycosyl hydrolase, all-beta CAK77_RS07385 36fa199965d65c8be334cb5c4ad9dd0a 690 Gene3D G3DSA:3.20.20.80 222 580 1.5E-65 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAK77_RS07385 36fa199965d65c8be334cb5c4ad9dd0a 690 Pfam PF11896 Domain of unknown function (DUF3416) 3 215 6.6E-57 T 06-07-2017 IPR021828 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase, domain N/S GO:0004553 KEGG: 00500+2.4.99.16 CAK77_RS07385 36fa199965d65c8be334cb5c4ad9dd0a 690 Pfam PF00128 Alpha amylase, catalytic domain 256 347 2.2E-4 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CAK77_RS07385 36fa199965d65c8be334cb5c4ad9dd0a 690 SMART SM00642 221 560 2.4E-4 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CAK77_RS13805 059de569b31e9f40a39b0013f3bf370e 189 Hamap MF_00328 Guanylate kinase [gmk]. 5 189 33.532 T 06-07-2017 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 CAK77_RS13805 059de569b31e9f40a39b0013f3bf370e 189 Pfam PF00625 Guanylate kinase 7 186 5.9E-43 T 06-07-2017 IPR008145 Guanylate kinase/L-type calcium channel beta subunit CAK77_RS13805 059de569b31e9f40a39b0013f3bf370e 189 Gene3D G3DSA:3.40.50.300 19 47 3.7E-4 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS13805 059de569b31e9f40a39b0013f3bf370e 189 Gene3D G3DSA:3.40.50.300 90 187 1.2E-38 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS13805 059de569b31e9f40a39b0013f3bf370e 189 Gene3D G3DSA:3.40.50.300 5 18 1.2E-38 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS13805 059de569b31e9f40a39b0013f3bf370e 189 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 7 186 1.1E-64 T 06-07-2017 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 CAK77_RS13805 059de569b31e9f40a39b0013f3bf370e 189 SMART SM00072 6 189 1.7E-65 T 06-07-2017 IPR008145 Guanylate kinase/L-type calcium channel beta subunit CAK77_RS13805 059de569b31e9f40a39b0013f3bf370e 189 Gene3D G3DSA:3.30.63.10 48 89 1.6E-24 T 06-07-2017 CAK77_RS13805 059de569b31e9f40a39b0013f3bf370e 189 SUPERFAMILY SSF52540 5 187 1.18E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS13805 059de569b31e9f40a39b0013f3bf370e 189 ProSitePatterns PS00856 Guanylate kinase-like signature. 41 58 - T 06-07-2017 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 CAK77_RS10740 be52d21325d12c639dd39f5f4de6f2e6 565 SUPERFAMILY SSF51556 90 150 2.08E-31 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK77_RS10740 be52d21325d12c639dd39f5f4de6f2e6 565 SUPERFAMILY SSF51556 216 495 2.08E-31 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK77_RS10740 be52d21325d12c639dd39f5f4de6f2e6 565 SUPERFAMILY SSF51338 40 108 1.73E-13 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK77_RS10740 be52d21325d12c639dd39f5f4de6f2e6 565 Pfam PF07969 Amidohydrolase family 79 563 2.1E-86 T 06-07-2017 IPR013108 Amidohydrolase 3 CAK77_RS10740 be52d21325d12c639dd39f5f4de6f2e6 565 Gene3D G3DSA:2.30.40.10 35 118 1.0E-13 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK77_RS10740 be52d21325d12c639dd39f5f4de6f2e6 565 Gene3D G3DSA:3.20.20.140 218 494 1.5E-28 T 06-07-2017 CAK77_RS19795 a6b3338b854671e4e9d1978ccbb87f9b 382 Pfam PF13193 AMP-binding enzyme C-terminal domain 297 371 7.0E-19 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAK77_RS19795 a6b3338b854671e4e9d1978ccbb87f9b 382 Gene3D G3DSA:2.30.38.10 224 280 2.5E-10 T 06-07-2017 CAK77_RS19795 a6b3338b854671e4e9d1978ccbb87f9b 382 Pfam PF00501 AMP-binding enzyme 55 287 6.2E-32 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK77_RS19795 a6b3338b854671e4e9d1978ccbb87f9b 382 Gene3D G3DSA:3.30.300.30 282 380 6.3E-25 T 06-07-2017 CAK77_RS19795 a6b3338b854671e4e9d1978ccbb87f9b 382 SUPERFAMILY SSF56801 15 381 8.37E-74 T 06-07-2017 CAK77_RS19795 a6b3338b854671e4e9d1978ccbb87f9b 382 Gene3D G3DSA:3.40.50.980 60 221 1.8E-21 T 06-07-2017 CAK77_RS24130 a91e2b160ca0fe916ead20522130d21b 184 Gene3D G3DSA:1.10.10.10 1 90 2.5E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS24130 a91e2b160ca0fe916ead20522130d21b 184 SUPERFAMILY SSF46785 2 174 8.51E-33 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS24130 a91e2b160ca0fe916ead20522130d21b 184 Pfam PF03551 Transcriptional regulator PadR-like family 6 85 8.9E-18 T 06-07-2017 IPR005149 Transcription regulator PadR, N-terminal CAK77_RS17900 ad6198a00a3fcc7826cc9417e2ac4332 409 Pfam PF00487 Fatty acid desaturase 133 346 2.9E-28 T 06-07-2017 IPR005804 Fatty acid desaturase domain GO:0006629 CAK77_RS14105 f34b4ed953e79eafad9fe89c05c3f958 202 Pfam PF07499 RuvA, C-terminal domain 149 199 7.2E-12 T 06-07-2017 IPR011114 DNA helicase, Holliday junction RuvA type, domain III, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 CAK77_RS14105 f34b4ed953e79eafad9fe89c05c3f958 202 Gene3D G3DSA:1.10.8.10 145 202 5.6E-23 T 06-07-2017 CAK77_RS14105 f34b4ed953e79eafad9fe89c05c3f958 202 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 199 28.844 T 06-07-2017 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 CAK77_RS14105 f34b4ed953e79eafad9fe89c05c3f958 202 Pfam PF14520 Helix-hairpin-helix domain 71 129 3.2E-16 T 06-07-2017 CAK77_RS14105 f34b4ed953e79eafad9fe89c05c3f958 202 SUPERFAMILY SSF46929 149 200 3.92E-10 T 06-07-2017 IPR011114 DNA helicase, Holliday junction RuvA type, domain III, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 CAK77_RS14105 f34b4ed953e79eafad9fe89c05c3f958 202 SUPERFAMILY SSF50249 2 62 4.97E-13 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS14105 f34b4ed953e79eafad9fe89c05c3f958 202 Pfam PF01330 RuvA N terminal domain 2 61 1.2E-17 T 06-07-2017 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 CAK77_RS14105 f34b4ed953e79eafad9fe89c05c3f958 202 SUPERFAMILY SSF47781 65 133 2.22E-19 T 06-07-2017 IPR010994 RuvA domain 2-like CAK77_RS14105 f34b4ed953e79eafad9fe89c05c3f958 202 SMART SM00278 107 126 1.1 T 06-07-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CAK77_RS14105 f34b4ed953e79eafad9fe89c05c3f958 202 SMART SM00278 72 91 99.0 T 06-07-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CAK77_RS14105 f34b4ed953e79eafad9fe89c05c3f958 202 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 192 2.2E-38 T 06-07-2017 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 CAK77_RS14105 f34b4ed953e79eafad9fe89c05c3f958 202 Gene3D G3DSA:1.10.150.20 68 133 6.1E-25 T 06-07-2017 CAK77_RS14105 f34b4ed953e79eafad9fe89c05c3f958 202 Gene3D G3DSA:2.40.50.140 2 63 5.1E-22 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS07460 efcc0be40dcc11a1a71ae52fbd3db0c9 253 SUPERFAMILY SSF56281 2 253 1.97E-46 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK77_RS07460 efcc0be40dcc11a1a71ae52fbd3db0c9 253 Pfam PF12706 Beta-lactamase superfamily domain 49 221 5.1E-19 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK77_RS07460 efcc0be40dcc11a1a71ae52fbd3db0c9 253 Gene3D G3DSA:3.60.15.10 2 251 3.5E-50 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK77_RS07460 efcc0be40dcc11a1a71ae52fbd3db0c9 253 SMART SM00849 18 220 1.3E-7 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK77_RS16285 46d78a716947a5f6860b11135ce0ecc5 294 Gene3D G3DSA:3.20.20.30 16 293 3.2E-52 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS16285 46d78a716947a5f6860b11135ce0ecc5 294 SUPERFAMILY SSF51679 1 292 1.7E-50 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS16285 46d78a716947a5f6860b11135ce0ecc5 294 Pfam PF00296 Luciferase-like monooxygenase 17 209 3.2E-38 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS00840 9f47afced0e4e2fcc49a26bdbfd4d453 579 SUPERFAMILY SSF52518 358 554 4.07E-53 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK77_RS00840 9f47afced0e4e2fcc49a26bdbfd4d453 579 SUPERFAMILY SSF52518 2 176 5.54E-45 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK77_RS00840 9f47afced0e4e2fcc49a26bdbfd4d453 579 Gene3D G3DSA:3.40.50.970 2 174 2.6E-52 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK77_RS00840 9f47afced0e4e2fcc49a26bdbfd4d453 579 Gene3D G3DSA:3.40.50.1220 189 340 4.0E-39 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAK77_RS00840 9f47afced0e4e2fcc49a26bdbfd4d453 579 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 4 169 7.7E-44 T 06-07-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CAK77_RS00840 9f47afced0e4e2fcc49a26bdbfd4d453 579 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 191 319 1.6E-27 T 06-07-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CAK77_RS00840 9f47afced0e4e2fcc49a26bdbfd4d453 579 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 381 527 3.2E-34 T 06-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CAK77_RS00840 9f47afced0e4e2fcc49a26bdbfd4d453 579 SUPERFAMILY SSF52467 185 352 1.03E-38 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAK77_RS00840 9f47afced0e4e2fcc49a26bdbfd4d453 579 Gene3D G3DSA:3.40.50.970 355 546 9.3E-52 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK77_RS15355 03e987bfa649f27aec02172346690b12 291 Gene3D G3DSA:3.20.20.70 4 291 1.2E-97 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK77_RS15355 03e987bfa649f27aec02172346690b12 291 Pfam PF00701 Dihydrodipicolinate synthetase family 5 286 7.8E-75 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAK77_RS15355 03e987bfa649f27aec02172346690b12 291 PRINTS PR00146 Dihydrodipicolinate synthase signature 37 58 4.5E-26 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAK77_RS15355 03e987bfa649f27aec02172346690b12 291 PRINTS PR00146 Dihydrodipicolinate synthase signature 73 91 4.5E-26 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAK77_RS15355 03e987bfa649f27aec02172346690b12 291 PRINTS PR00146 Dihydrodipicolinate synthase signature 105 121 4.5E-26 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAK77_RS15355 03e987bfa649f27aec02172346690b12 291 PRINTS PR00146 Dihydrodipicolinate synthase signature 130 147 4.5E-26 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAK77_RS15355 03e987bfa649f27aec02172346690b12 291 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 135 165 - T 06-07-2017 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAK77_RS15355 03e987bfa649f27aec02172346690b12 291 SMART SM01130 3 289 6.3E-109 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAK77_RS15355 03e987bfa649f27aec02172346690b12 291 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 40 57 - T 06-07-2017 IPR020624 Schiff base-forming aldolase, conserved site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAK77_RS15355 03e987bfa649f27aec02172346690b12 291 PIRSF PIRSF001365 2 291 2.6E-77 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAK77_RS15355 03e987bfa649f27aec02172346690b12 291 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 7 282 1.8E-70 T 06-07-2017 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAK77_RS15355 03e987bfa649f27aec02172346690b12 291 SUPERFAMILY SSF51569 4 290 6.49E-89 T 06-07-2017 CAK77_RS15355 03e987bfa649f27aec02172346690b12 291 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 3 287 52.74 T 06-07-2017 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAK77_RS22250 679bd8f8b7f2b43271e5e308f22738bd 110 Gene3D G3DSA:3.30.1460.30 6 104 3.7E-6 T 06-07-2017 IPR007076 TfoX, N-terminal CAK77_RS22250 679bd8f8b7f2b43271e5e308f22738bd 110 SUPERFAMILY SSF159894 5 104 7.59E-12 T 06-07-2017 CAK77_RS22250 679bd8f8b7f2b43271e5e308f22738bd 110 Pfam PF04993 TfoX N-terminal domain 15 104 2.6E-16 T 06-07-2017 IPR007076 TfoX, N-terminal CAK77_RS02405 825269e3a62013f64bcfc5083f4260af 125 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 23 38 7.3E-11 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK77_RS02405 825269e3a62013f64bcfc5083f4260af 125 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 70 85 7.3E-11 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK77_RS02405 825269e3a62013f64bcfc5083f4260af 125 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 55 70 7.3E-11 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK77_RS02405 825269e3a62013f64bcfc5083f4260af 125 SUPERFAMILY SSF46785 13 96 5.16E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS02405 825269e3a62013f64bcfc5083f4260af 125 Pfam PF01022 Bacterial regulatory protein, arsR family 28 74 4.1E-13 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK77_RS02405 825269e3a62013f64bcfc5083f4260af 125 Gene3D G3DSA:1.10.10.10 14 100 5.4E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS02405 825269e3a62013f64bcfc5083f4260af 125 SMART SM00418 21 99 1.8E-20 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK77_RS00185 825269e3a62013f64bcfc5083f4260af 125 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 23 38 7.3E-11 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK77_RS00185 825269e3a62013f64bcfc5083f4260af 125 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 70 85 7.3E-11 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK77_RS00185 825269e3a62013f64bcfc5083f4260af 125 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 55 70 7.3E-11 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK77_RS00185 825269e3a62013f64bcfc5083f4260af 125 SUPERFAMILY SSF46785 13 96 5.16E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS00185 825269e3a62013f64bcfc5083f4260af 125 Pfam PF01022 Bacterial regulatory protein, arsR family 28 74 4.1E-13 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK77_RS00185 825269e3a62013f64bcfc5083f4260af 125 Gene3D G3DSA:1.10.10.10 14 100 5.4E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS00185 825269e3a62013f64bcfc5083f4260af 125 SMART SM00418 21 99 1.8E-20 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK77_RS00030 164b854ee5fc2fd7bb3a44dbf5660308 183 Pfam PF05258 Protein of unknown function (DUF721) 72 158 3.9E-23 T 06-07-2017 IPR007922 Protein of unknown function DUF721/UPF0232 CAK77_RS00030 164b854ee5fc2fd7bb3a44dbf5660308 183 Hamap MF_00630 UPF0232 protein . 1 170 33.376 T 06-07-2017 IPR023007 Uncharacterised protein family UPF0232, actinobacteria CAK77_RS16750 cf775243630b2205540273a7ae63d42d 146 Gene3D G3DSA:1.10.10.10 2 53 2.9E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS16750 cf775243630b2205540273a7ae63d42d 146 Pfam PF13412 Winged helix-turn-helix DNA-binding 1 48 2.2E-19 T 06-07-2017 CAK77_RS16750 cf775243630b2205540273a7ae63d42d 146 ProSitePatterns PS00519 AsnC-type HTH domain signature. 19 45 - T 06-07-2017 IPR019885 Transcription regulator HTH, AsnC-type, conserved site CAK77_RS16750 cf775243630b2205540273a7ae63d42d 146 Pfam PF01037 Lrp/AsnC ligand binding domain 78 140 1.2E-10 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CAK77_RS16750 cf775243630b2205540273a7ae63d42d 146 SMART SM00344 1 110 4.2E-37 T 06-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CAK77_RS16750 cf775243630b2205540273a7ae63d42d 146 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 2.8E-17 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAK77_RS16750 cf775243630b2205540273a7ae63d42d 146 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 2.8E-17 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAK77_RS16750 cf775243630b2205540273a7ae63d42d 146 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 2.8E-17 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAK77_RS16750 cf775243630b2205540273a7ae63d42d 146 SUPERFAMILY SSF54909 72 145 3.75E-10 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAK77_RS16750 cf775243630b2205540273a7ae63d42d 146 SUPERFAMILY SSF46785 1 60 1.49E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS16750 cf775243630b2205540273a7ae63d42d 146 Gene3D G3DSA:3.30.70.920 54 137 1.3E-15 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CAK77_RS10120 cbac612a3516e27cb7cfd2dab5c5e9a6 399 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 249 397 5.3E-42 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS10120 cbac612a3516e27cb7cfd2dab5c5e9a6 399 Gene3D G3DSA:1.10.540.10 23 140 3.3E-28 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS10120 cbac612a3516e27cb7cfd2dab5c5e9a6 399 Gene3D G3DSA:2.40.110.10 143 237 1.0E-37 T 06-07-2017 CAK77_RS10120 cbac612a3516e27cb7cfd2dab5c5e9a6 399 SUPERFAMILY SSF56645 22 260 8.51E-74 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK77_RS10120 cbac612a3516e27cb7cfd2dab5c5e9a6 399 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 26 138 5.5E-23 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS10120 cbac612a3516e27cb7cfd2dab5c5e9a6 399 Gene3D G3DSA:1.20.140.10 238 397 3.5E-57 T 06-07-2017 CAK77_RS10120 cbac612a3516e27cb7cfd2dab5c5e9a6 399 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 356 375 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CAK77_RS10120 cbac612a3516e27cb7cfd2dab5c5e9a6 399 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 143 237 1.7E-23 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAK77_RS10120 cbac612a3516e27cb7cfd2dab5c5e9a6 399 SUPERFAMILY SSF47203 248 397 1.61E-43 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS06000 5ac3edc969338aa7885ff07028b421d5 465 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 8 296 1.1E-67 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAK77_RS06000 5ac3edc969338aa7885ff07028b421d5 465 TIGRFAM TIGR01137 cysta_beta: cystathionine beta-synthase 3 457 1.0E-203 T 06-07-2017 IPR005857 Cystathionine beta-synthase GO:0004122|GO:0005737|GO:0019343 KEGG: 00260+4.2.1.22|KEGG: 00270+4.2.1.22|MetaCyc: PWY-801 CAK77_RS06000 5ac3edc969338aa7885ff07028b421d5 465 Gene3D G3DSA:3.10.580.10 342 458 9.0E-23 T 06-07-2017 CAK77_RS06000 5ac3edc969338aa7885ff07028b421d5 465 Pfam PF00571 CBS domain 406 457 3.8E-8 T 06-07-2017 IPR000644 CBS domain CAK77_RS06000 5ac3edc969338aa7885ff07028b421d5 465 Pfam PF00571 CBS domain 342 395 1.1E-7 T 06-07-2017 IPR000644 CBS domain CAK77_RS06000 5ac3edc969338aa7885ff07028b421d5 465 SMART SM00116 413 458 0.039 T 06-07-2017 IPR000644 CBS domain CAK77_RS06000 5ac3edc969338aa7885ff07028b421d5 465 SMART SM00116 343 396 7.4E-5 T 06-07-2017 IPR000644 CBS domain CAK77_RS06000 5ac3edc969338aa7885ff07028b421d5 465 Gene3D G3DSA:3.40.50.1100 43 147 2.6E-38 T 06-07-2017 CAK77_RS06000 5ac3edc969338aa7885ff07028b421d5 465 Gene3D G3DSA:3.40.50.1100 153 313 1.7E-69 T 06-07-2017 CAK77_RS06000 5ac3edc969338aa7885ff07028b421d5 465 Gene3D G3DSA:3.40.50.1100 1 42 1.7E-69 T 06-07-2017 CAK77_RS06000 5ac3edc969338aa7885ff07028b421d5 465 SUPERFAMILY SSF54631 329 457 5.43E-21 T 06-07-2017 CAK77_RS06000 5ac3edc969338aa7885ff07028b421d5 465 SUPERFAMILY SSF53686 1 317 1.96E-96 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAK77_RS14530 c415752633cd05fdda90bddfbae86750 303 Pfam PF13391 HNH endonuclease 210 259 5.2E-9 T 06-07-2017 IPR003615 HNH nuclease CAK77_RS04420 f516840d6757b83fc654d38f16e01738 330 SMART SM00729 13 209 6.4E-9 T 06-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CAK77_RS04420 f516840d6757b83fc654d38f16e01738 330 Gene3D G3DSA:3.20.20.70 3 307 3.0E-72 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK77_RS04420 f516840d6757b83fc654d38f16e01738 330 Pfam PF06463 Molybdenum Cofactor Synthesis C 185 312 6.4E-37 T 06-07-2017 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CAK77_RS04420 f516840d6757b83fc654d38f16e01738 330 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 4 330 2.4E-106 T 06-07-2017 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CAK77_RS04420 f516840d6757b83fc654d38f16e01738 330 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 19 30 - T 06-07-2017 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CAK77_RS04420 f516840d6757b83fc654d38f16e01738 330 Pfam PF04055 Radical SAM superfamily 18 179 1.6E-26 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 CAK77_RS04420 f516840d6757b83fc654d38f16e01738 330 Pfam PF13394 4Fe-4S single cluster domain 20 102 1.7E-6 T 06-07-2017 CAK77_RS04420 f516840d6757b83fc654d38f16e01738 330 SUPERFAMILY SSF102114 3 278 8.5E-67 T 06-07-2017 CAK77_RS04420 f516840d6757b83fc654d38f16e01738 330 Hamap MF_01225_B Cyclic pyranopterin monophosphate synthase [moaA]. 4 330 38.414 T 06-07-2017 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CAK77_RS18420 e5f1b93cb053451d936058904bdd3adc 861 SMART SM00382 344 528 6.5E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS18420 e5f1b93cb053451d936058904bdd3adc 861 SUPERFAMILY SSF49879 194 303 4.59E-22 T 06-07-2017 IPR008984 SMAD/FHA domain GO:0005515 CAK77_RS18420 e5f1b93cb053451d936058904bdd3adc 861 Gene3D G3DSA:2.60.200.20 230 304 1.7E-18 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CAK77_RS18420 e5f1b93cb053451d936058904bdd3adc 861 Pfam PF00498 FHA domain 233 296 2.2E-14 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CAK77_RS18420 e5f1b93cb053451d936058904bdd3adc 861 Pfam PF00498 FHA domain 27 89 8.0E-13 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CAK77_RS18420 e5f1b93cb053451d936058904bdd3adc 861 ProSitePatterns PS00211 ABC transporters family signature. 454 468 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK77_RS18420 e5f1b93cb053451d936058904bdd3adc 861 Pfam PF01061 ABC-2 type transporter 598 808 3.5E-16 T 06-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CAK77_RS18420 e5f1b93cb053451d936058904bdd3adc 861 SUPERFAMILY SSF49879 15 99 1.26E-19 T 06-07-2017 IPR008984 SMAD/FHA domain GO:0005515 CAK77_RS18420 e5f1b93cb053451d936058904bdd3adc 861 SMART SM00240 25 75 1.1E-11 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CAK77_RS18420 e5f1b93cb053451d936058904bdd3adc 861 SMART SM00240 232 282 1.4E-9 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CAK77_RS18420 e5f1b93cb053451d936058904bdd3adc 861 Pfam PF00005 ABC transporter 335 482 8.8E-33 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK77_RS18420 e5f1b93cb053451d936058904bdd3adc 861 SUPERFAMILY SSF52540 319 543 1.31E-54 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS18420 e5f1b93cb053451d936058904bdd3adc 861 Gene3D G3DSA:2.60.200.20 14 90 2.2E-17 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CAK77_RS18420 e5f1b93cb053451d936058904bdd3adc 861 Gene3D G3DSA:3.40.50.300 316 543 7.5E-64 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS11485 eb60f9f1407f258fa2f294eba5a27f23 268 Gene3D G3DSA:3.10.290.10 6 95 5.6E-19 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 CAK77_RS11485 eb60f9f1407f258fa2f294eba5a27f23 268 SUPERFAMILY SSF55174 5 57 2.8E-8 T 06-07-2017 CAK77_RS11485 eb60f9f1407f258fa2f294eba5a27f23 268 SUPERFAMILY SSF53335 62 248 4.15E-20 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS11485 eb60f9f1407f258fa2f294eba5a27f23 268 Pfam PF01728 FtsJ-like methyltransferase 62 247 2.5E-20 T 06-07-2017 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 CAK77_RS11485 eb60f9f1407f258fa2f294eba5a27f23 268 PIRSF PIRSF005578 1 265 3.1E-91 T 06-07-2017 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 CAK77_RS11485 eb60f9f1407f258fa2f294eba5a27f23 268 SMART SM00363 5 71 1.7E-8 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 CAK77_RS11485 eb60f9f1407f258fa2f294eba5a27f23 268 Gene3D G3DSA:3.40.50.150 96 169 1.2E-8 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS11485 eb60f9f1407f258fa2f294eba5a27f23 268 Pfam PF01479 S4 domain 6 42 1.2E-8 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 CAK77_RS11485 eb60f9f1407f258fa2f294eba5a27f23 268 TIGRFAM TIGR00478 tly: TlyA family rRNA methyltransferase/putative hemolysin 6 241 1.0E-56 T 06-07-2017 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 CAK77_RS17225 674cfb65e372cc0ae0b6f804db41a434 146 SUPERFAMILY SSF46785 7 139 3.39E-33 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS17225 674cfb65e372cc0ae0b6f804db41a434 146 Gene3D G3DSA:1.10.10.10 7 101 1.4E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS17225 674cfb65e372cc0ae0b6f804db41a434 146 Pfam PF01638 HxlR-like helix-turn-helix 17 103 2.3E-22 T 06-07-2017 IPR002577 Helix-turn-helix, HxlR type CAK77_RS15810 cebaccd9792c9f3829bb78ea6e30454f 312 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 255 277 1.1E-16 T 06-07-2017 CAK77_RS15810 cebaccd9792c9f3829bb78ea6e30454f 312 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 102 120 1.1E-16 T 06-07-2017 CAK77_RS15810 cebaccd9792c9f3829bb78ea6e30454f 312 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 144 162 1.1E-16 T 06-07-2017 CAK77_RS15810 cebaccd9792c9f3829bb78ea6e30454f 312 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 1.1E-16 T 06-07-2017 CAK77_RS15810 cebaccd9792c9f3829bb78ea6e30454f 312 Gene3D G3DSA:3.50.50.60 4 110 4.1E-22 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS15810 cebaccd9792c9f3829bb78ea6e30454f 312 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 6 28 9.6E-21 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAK77_RS15810 cebaccd9792c9f3829bb78ea6e30454f 312 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 140 164 9.6E-21 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAK77_RS15810 cebaccd9792c9f3829bb78ea6e30454f 312 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 125 137 9.6E-21 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAK77_RS15810 cebaccd9792c9f3829bb78ea6e30454f 312 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 103 111 9.6E-21 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAK77_RS15810 cebaccd9792c9f3829bb78ea6e30454f 312 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 265 283 9.6E-21 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAK77_RS15810 cebaccd9792c9f3829bb78ea6e30454f 312 Gene3D G3DSA:3.50.50.60 131 227 1.7E-34 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS15810 cebaccd9792c9f3829bb78ea6e30454f 312 SUPERFAMILY SSF51905 5 300 5.04E-35 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS15810 cebaccd9792c9f3829bb78ea6e30454f 312 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 287 9.1E-27 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS15810 cebaccd9792c9f3829bb78ea6e30454f 312 Gene3D G3DSA:3.50.50.60 255 278 1.7E-5 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS15810 cebaccd9792c9f3829bb78ea6e30454f 312 Gene3D G3DSA:3.50.50.60 111 130 1.7E-5 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS17845 529d544b882cca92f568571e8a0386d8 576 PRINTS PR00344 Bacterial sensor protein C-terminal signature 440 454 6.2E-12 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK77_RS17845 529d544b882cca92f568571e8a0386d8 576 PRINTS PR00344 Bacterial sensor protein C-terminal signature 458 468 6.2E-12 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK77_RS17845 529d544b882cca92f568571e8a0386d8 576 PRINTS PR00344 Bacterial sensor protein C-terminal signature 475 493 6.2E-12 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK77_RS17845 529d544b882cca92f568571e8a0386d8 576 PRINTS PR00344 Bacterial sensor protein C-terminal signature 499 512 6.2E-12 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK77_RS17845 529d544b882cca92f568571e8a0386d8 576 SMART SM00387 404 515 1.5E-29 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS17845 529d544b882cca92f568571e8a0386d8 576 SMART SM00304 231 283 2.2E-11 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAK77_RS17845 529d544b882cca92f568571e8a0386d8 576 SMART SM00388 291 358 2.6E-15 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK77_RS17845 529d544b882cca92f568571e8a0386d8 576 Pfam PF00512 His Kinase A (phospho-acceptor) domain 292 358 1.4E-14 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK77_RS17845 529d544b882cca92f568571e8a0386d8 576 SUPERFAMILY SSF55874 348 517 2.23E-40 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS17845 529d544b882cca92f568571e8a0386d8 576 Gene3D G3DSA:1.10.287.130 282 354 1.4E-15 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK77_RS17845 529d544b882cca92f568571e8a0386d8 576 SUPERFAMILY SSF47384 274 358 5.49E-17 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK77_RS17845 529d544b882cca92f568571e8a0386d8 576 Pfam PF00672 HAMP domain 212 279 7.2E-12 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAK77_RS17845 529d544b882cca92f568571e8a0386d8 576 SUPERFAMILY SSF158472 231 280 9.15E-8 T 06-07-2017 CAK77_RS17845 529d544b882cca92f568571e8a0386d8 576 Gene3D G3DSA:3.30.565.10 361 515 7.4E-37 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS17845 529d544b882cca92f568571e8a0386d8 576 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 405 513 1.1E-17 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS13280 7707780909b308904af162d0263e50ae 759 Pfam PF02310 B12 binding domain 627 742 4.8E-15 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CAK77_RS13280 7707780909b308904af162d0263e50ae 759 Pfam PF01642 Methylmalonyl-CoA mutase 58 582 7.5E-230 T 06-07-2017 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CAK77_RS13280 7707780909b308904af162d0263e50ae 759 SUPERFAMILY SSF51703 46 584 1.78E-211 T 06-07-2017 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CAK77_RS13280 7707780909b308904af162d0263e50ae 759 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 624 753 5.1E-63 T 06-07-2017 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CAK77_RS13280 7707780909b308904af162d0263e50ae 759 SUPERFAMILY SSF52242 588 755 8.24E-57 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CAK77_RS13280 7707780909b308904af162d0263e50ae 759 ProSitePatterns PS00544 Methylmalonyl-CoA mutase signature. 403 428 - T 06-07-2017 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CAK77_RS13280 7707780909b308904af162d0263e50ae 759 Gene3D G3DSA:3.20.20.240 56 526 5.9E-203 T 06-07-2017 IPR014348 Cobalamin (vitamin B12)-dependent enzyme, catalytic subdomain GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CAK77_RS13280 7707780909b308904af162d0263e50ae 759 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 56 589 1.6E-281 T 06-07-2017 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CAK77_RS13280 7707780909b308904af162d0263e50ae 759 Gene3D G3DSA:3.40.50.280 588 753 2.8E-69 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CAK77_RS13260 22705b7f531d1a9aad5fbdd23bb88b28 290 SUPERFAMILY SSF46785 6 87 4.35E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS13260 22705b7f531d1a9aad5fbdd23bb88b28 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.1E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK77_RS13260 22705b7f531d1a9aad5fbdd23bb88b28 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.1E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK77_RS13260 22705b7f531d1a9aad5fbdd23bb88b28 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.1E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK77_RS13260 22705b7f531d1a9aad5fbdd23bb88b28 290 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 62 9.5E-16 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK77_RS13260 22705b7f531d1a9aad5fbdd23bb88b28 290 Gene3D G3DSA:1.10.10.10 6 87 3.7E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS13260 22705b7f531d1a9aad5fbdd23bb88b28 290 Gene3D G3DSA:3.40.190.10 90 176 7.0E-18 T 06-07-2017 CAK77_RS13260 22705b7f531d1a9aad5fbdd23bb88b28 290 SUPERFAMILY SSF53850 89 288 2.17E-42 T 06-07-2017 CAK77_RS13260 22705b7f531d1a9aad5fbdd23bb88b28 290 Pfam PF03466 LysR substrate binding domain 88 287 4.3E-48 T 06-07-2017 IPR005119 LysR, substrate-binding CAK77_RS13260 22705b7f531d1a9aad5fbdd23bb88b28 290 Gene3D G3DSA:3.40.190.10 177 258 6.0E-28 T 06-07-2017 CAK77_RS13520 f5161e70af6a4c3e18703da0c2eb4364 709 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 31 366 8.3E-140 T 06-07-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CAK77_RS13520 f5161e70af6a4c3e18703da0c2eb4364 709 ProSitePatterns PS00801 Transketolase signature 1. 39 59 - T 06-07-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CAK77_RS13520 f5161e70af6a4c3e18703da0c2eb4364 709 SMART SM00861 383 565 4.3E-62 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain CAK77_RS13520 f5161e70af6a4c3e18703da0c2eb4364 709 Pfam PF02780 Transketolase, C-terminal domain 590 697 1.4E-10 T 06-07-2017 IPR033248 Transketolase, C-terminal domain CAK77_RS13520 f5161e70af6a4c3e18703da0c2eb4364 709 ProSitePatterns PS00802 Transketolase signature 2. 505 521 - T 06-07-2017 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CAK77_RS13520 f5161e70af6a4c3e18703da0c2eb4364 709 Gene3D G3DSA:3.40.50.970 27 352 4.3E-105 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK77_RS13520 f5161e70af6a4c3e18703da0c2eb4364 709 Pfam PF02779 Transketolase, pyrimidine binding domain 382 563 4.9E-43 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain CAK77_RS13520 f5161e70af6a4c3e18703da0c2eb4364 709 SUPERFAMILY SSF52518 22 352 1.77E-99 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK77_RS13520 f5161e70af6a4c3e18703da0c2eb4364 709 TIGRFAM TIGR00232 tktlase_bact: transketolase 34 703 2.6E-232 T 06-07-2017 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 CAK77_RS13520 f5161e70af6a4c3e18703da0c2eb4364 709 SUPERFAMILY SSF52518 369 567 1.12E-60 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK77_RS13520 f5161e70af6a4c3e18703da0c2eb4364 709 Gene3D G3DSA:3.40.50.970 362 571 2.5E-69 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK77_RS13520 f5161e70af6a4c3e18703da0c2eb4364 709 Gene3D G3DSA:3.40.50.920 576 705 1.5E-45 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CAK77_RS13520 f5161e70af6a4c3e18703da0c2eb4364 709 SUPERFAMILY SSF52922 570 706 4.45E-39 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CAK77_RS23585 8537d286502ad4f8e7024b3af10b4744 216 SUPERFAMILY SSF52833 33 209 6.5E-14 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK77_RS23585 8537d286502ad4f8e7024b3af10b4744 216 Gene3D G3DSA:3.40.30.10 31 140 3.8E-13 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK77_RS23585 8537d286502ad4f8e7024b3af10b4744 216 Pfam PF13462 Thioredoxin 39 149 3.2E-6 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK77_RS22900 93f3e5d82e793edaf30795a5810433f9 288 Pfam PF02405 Permease MlaE 67 277 2.5E-57 T 06-07-2017 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 CAK77_RS06555 84f216560e6620c143442d0167caeab7 130 SUPERFAMILY SSF55811 1 122 3.79E-25 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAK77_RS06555 84f216560e6620c143442d0167caeab7 130 PRINTS PR00502 NUDIX hydrolase family signature 41 56 6.7E-7 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CAK77_RS06555 84f216560e6620c143442d0167caeab7 130 PRINTS PR00502 NUDIX hydrolase family signature 27 41 6.7E-7 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CAK77_RS06555 84f216560e6620c143442d0167caeab7 130 Pfam PF00293 NUDIX domain 3 116 4.7E-17 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 CAK77_RS06555 84f216560e6620c143442d0167caeab7 130 Gene3D G3DSA:3.90.79.10 1 121 4.2E-25 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAK77_RS06555 84f216560e6620c143442d0167caeab7 130 ProSitePatterns PS00893 Nudix box signature. 32 53 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CAK77_RS10365 134b019719ca2eee01258214fdfa99a1 289 Gene3D G3DSA:3.40.190.10 7 146 2.2E-38 T 06-07-2017 CAK77_RS10365 134b019719ca2eee01258214fdfa99a1 289 SUPERFAMILY SSF53850 8 213 3.62E-61 T 06-07-2017 CAK77_RS10365 134b019719ca2eee01258214fdfa99a1 289 Gene3D G3DSA:3.30.70.120 217 282 3.6E-24 T 06-07-2017 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal CAK77_RS10365 134b019719ca2eee01258214fdfa99a1 289 Pfam PF01634 ATP phosphoribosyltransferase 55 210 2.3E-41 T 06-07-2017 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 CAK77_RS10365 134b019719ca2eee01258214fdfa99a1 289 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 147 168 - T 06-07-2017 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 CAK77_RS10365 134b019719ca2eee01258214fdfa99a1 289 Pfam PF08029 HisG, C-terminal domain 215 284 3.4E-21 T 06-07-2017 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 CAK77_RS10365 134b019719ca2eee01258214fdfa99a1 289 SUPERFAMILY SSF54913 217 285 6.0E-18 T 06-07-2017 IPR011322 Nitrogen regulatory PII-like, alpha/beta CAK77_RS10365 134b019719ca2eee01258214fdfa99a1 289 Hamap MF_00079 ATP phosphoribosyltransferase [hisG]. 7 289 31.188 T 06-07-2017 IPR020621 ATP phosphoribosyltransferase HisG, long form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 CAK77_RS10365 134b019719ca2eee01258214fdfa99a1 289 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 8 188 5.7E-52 T 06-07-2017 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 CAK77_RS10365 134b019719ca2eee01258214fdfa99a1 289 TIGRFAM TIGR03455 HisG_C-term: ATP phosphoribosyltransferase, C-terminal domain 192 285 1.4E-25 T 06-07-2017 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 CAK77_RS07785 ae76e8d4c63f96e66acbbddd24ff027a 305 PIRSF PIRSF002936 4 305 3.7E-129 T 06-07-2017 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 CAK77_RS07785 ae76e8d4c63f96e66acbbddd24ff027a 305 TIGRFAM TIGR02039 CysD: sulfate adenylyltransferase, small subunit 13 305 1.1E-128 T 06-07-2017 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 CAK77_RS07785 ae76e8d4c63f96e66acbbddd24ff027a 305 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 34 259 2.2E-43 T 06-07-2017 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 CAK77_RS07785 ae76e8d4c63f96e66acbbddd24ff027a 305 SUPERFAMILY SSF52402 9 212 2.09E-60 T 06-07-2017 CAK77_RS07785 ae76e8d4c63f96e66acbbddd24ff027a 305 Gene3D G3DSA:3.40.50.620 246 254 1.2E-47 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS07785 ae76e8d4c63f96e66acbbddd24ff027a 305 Gene3D G3DSA:3.40.50.620 9 213 1.2E-47 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS05350 837fa9626cb52c8127ab4bd0d8e3cc79 526 PIRSF PIRSF000414 10 526 1.6E-191 T 06-07-2017 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CAK77_RS05350 837fa9626cb52c8127ab4bd0d8e3cc79 526 Pfam PF01808 AICARFT/IMPCHase bienzyme 147 460 5.4E-112 T 06-07-2017 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CAK77_RS05350 837fa9626cb52c8127ab4bd0d8e3cc79 526 Gene3D G3DSA:3.40.140.20 252 368 5.2E-44 T 06-07-2017 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CAK77_RS05350 837fa9626cb52c8127ab4bd0d8e3cc79 526 SUPERFAMILY SSF52335 16 205 5.8E-63 T 06-07-2017 IPR011607 Methylglyoxal synthase-like domain CAK77_RS05350 837fa9626cb52c8127ab4bd0d8e3cc79 526 Pfam PF02142 MGS-like domain 28 141 5.6E-23 T 06-07-2017 IPR011607 Methylglyoxal synthase-like domain CAK77_RS05350 837fa9626cb52c8127ab4bd0d8e3cc79 526 SMART SM00851 28 142 4.0E-44 T 06-07-2017 IPR011607 Methylglyoxal synthase-like domain CAK77_RS05350 837fa9626cb52c8127ab4bd0d8e3cc79 526 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 16 526 41.341 T 06-07-2017 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CAK77_RS05350 837fa9626cb52c8127ab4bd0d8e3cc79 526 Gene3D G3DSA:3.40.140.20 374 516 1.6E-49 T 06-07-2017 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CAK77_RS05350 837fa9626cb52c8127ab4bd0d8e3cc79 526 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 17 526 4.0E-166 T 06-07-2017 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CAK77_RS05350 837fa9626cb52c8127ab4bd0d8e3cc79 526 SMART SM00798 147 461 9.7E-174 T 06-07-2017 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CAK77_RS05350 837fa9626cb52c8127ab4bd0d8e3cc79 526 Gene3D G3DSA:3.40.50.1380 15 197 4.8E-76 T 06-07-2017 IPR011607 Methylglyoxal synthase-like domain CAK77_RS05350 837fa9626cb52c8127ab4bd0d8e3cc79 526 SUPERFAMILY SSF53927 223 526 5.52E-112 T 06-07-2017 IPR016193 Cytidine deaminase-like GO:0003824 CAK77_RS15185 2e28b346151bcf87956fdcc01cc6d462 262 Pfam PF00005 ABC transporter 37 185 3.7E-35 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK77_RS15185 2e28b346151bcf87956fdcc01cc6d462 262 Gene3D G3DSA:3.40.50.300 20 256 1.0E-82 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS15185 2e28b346151bcf87956fdcc01cc6d462 262 SMART SM00382 46 233 5.0E-17 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS15185 2e28b346151bcf87956fdcc01cc6d462 262 SUPERFAMILY SSF52540 21 255 5.97E-79 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS15185 2e28b346151bcf87956fdcc01cc6d462 262 PIRSF PIRSF039085 18 261 2.3E-109 T 06-07-2017 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CAK77_RS15185 2e28b346151bcf87956fdcc01cc6d462 262 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK77_RS20170 36e474231629158b049baf45ed03c1bf 229 Gene3D G3DSA:1.10.357.10 63 209 1.6E-17 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS20170 36e474231629158b049baf45ed03c1bf 229 Pfam PF00440 Bacterial regulatory proteins, tetR family 34 79 1.1E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS20170 36e474231629158b049baf45ed03c1bf 229 SUPERFAMILY SSF46689 21 96 6.16E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS20170 36e474231629158b049baf45ed03c1bf 229 ProSitePatterns PS01081 TetR-type HTH domain signature. 46 75 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CAK77_RS20170 36e474231629158b049baf45ed03c1bf 229 Gene3D G3DSA:1.10.10.60 22 62 2.0E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS04425 98961bc9a14c5e1eafb251a6cd929696 137 SMART SM00357 3 65 1.3E-21 T 06-07-2017 IPR011129 Cold shock protein GO:0003676 CAK77_RS04425 98961bc9a14c5e1eafb251a6cd929696 137 Gene3D G3DSA:2.40.50.140 2 68 2.2E-21 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS04425 98961bc9a14c5e1eafb251a6cd929696 137 Pfam PF00313 'Cold-shock' DNA-binding domain 3 62 1.4E-15 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAK77_RS04425 98961bc9a14c5e1eafb251a6cd929696 137 PRINTS PR00050 Cold shock protein signature 4 19 1.7E-11 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAK77_RS04425 98961bc9a14c5e1eafb251a6cd929696 137 PRINTS PR00050 Cold shock protein signature 24 33 1.7E-11 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAK77_RS04425 98961bc9a14c5e1eafb251a6cd929696 137 PRINTS PR00050 Cold shock protein signature 38 56 1.7E-11 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAK77_RS04425 98961bc9a14c5e1eafb251a6cd929696 137 SUPERFAMILY SSF50249 2 68 6.86E-16 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS09770 121d639fe39df4588ebb97d3f8abf1f4 387 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 6 344 37.92 T 06-07-2017 IPR000158 Cell division protein FtsZ GO:0005525 CAK77_RS09770 121d639fe39df4588ebb97d3f8abf1f4 387 SMART SM00864 10 202 2.3E-105 T 06-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CAK77_RS09770 121d639fe39df4588ebb97d3f8abf1f4 387 Gene3D G3DSA:3.30.1330.20 212 314 5.1E-48 T 06-07-2017 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-983189 CAK77_RS09770 121d639fe39df4588ebb97d3f8abf1f4 387 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 8 313 3.3E-126 T 06-07-2017 IPR000158 Cell division protein FtsZ GO:0005525 CAK77_RS09770 121d639fe39df4588ebb97d3f8abf1f4 387 ProSitePatterns PS01134 FtsZ protein signature 1. 41 75 - T 06-07-2017 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 CAK77_RS09770 121d639fe39df4588ebb97d3f8abf1f4 387 SMART SM00865 204 321 5.7E-55 T 06-07-2017 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-983189 CAK77_RS09770 121d639fe39df4588ebb97d3f8abf1f4 387 PRINTS PR00423 Cell division protein FtsZ signature 186 208 1.1E-50 T 06-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CAK77_RS09770 121d639fe39df4588ebb97d3f8abf1f4 387 PRINTS PR00423 Cell division protein FtsZ signature 95 115 1.1E-50 T 06-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CAK77_RS09770 121d639fe39df4588ebb97d3f8abf1f4 387 PRINTS PR00423 Cell division protein FtsZ signature 209 230 1.1E-50 T 06-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CAK77_RS09770 121d639fe39df4588ebb97d3f8abf1f4 387 PRINTS PR00423 Cell division protein FtsZ signature 123 144 1.1E-50 T 06-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CAK77_RS09770 121d639fe39df4588ebb97d3f8abf1f4 387 ProSitePatterns PS01135 FtsZ protein signature 2. 94 115 - T 06-07-2017 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 CAK77_RS09770 121d639fe39df4588ebb97d3f8abf1f4 387 SUPERFAMILY SSF55307 201 314 3.2E-43 T 06-07-2017 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 CAK77_RS09770 121d639fe39df4588ebb97d3f8abf1f4 387 SUPERFAMILY SSF52490 9 205 7.98E-67 T 06-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CAK77_RS09770 121d639fe39df4588ebb97d3f8abf1f4 387 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 11 169 4.2E-40 T 06-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CAK77_RS09770 121d639fe39df4588ebb97d3f8abf1f4 387 Pfam PF12327 FtsZ family, C-terminal domain 219 313 3.2E-35 T 06-07-2017 IPR024757 Cell division protein FtsZ, C-terminal CAK77_RS09770 121d639fe39df4588ebb97d3f8abf1f4 387 Gene3D G3DSA:3.40.50.1440 11 211 9.2E-91 T 06-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CAK77_RS16150 51e6718e0582d09e489f49993efead09 1199 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 1180 8.0E-73 T 06-07-2017 IPR003395 RecF/RecN/SMC, N-terminal CAK77_RS16150 51e6718e0582d09e489f49993efead09 1199 PIRSF PIRSF005719 1 1195 7.1E-266 T 06-07-2017 IPR024704 Structural maintenance of chromosomes protein CAK77_RS16150 51e6718e0582d09e489f49993efead09 1199 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 3 1187 0.0 T 06-07-2017 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 CAK77_RS16150 51e6718e0582d09e489f49993efead09 1199 Pfam PF06470 SMC proteins Flexible Hinge Domain 510 623 1.4E-20 T 06-07-2017 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 CAK77_RS16150 51e6718e0582d09e489f49993efead09 1199 SMART SM00968 510 624 5.9E-20 T 06-07-2017 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 CAK77_RS16150 51e6718e0582d09e489f49993efead09 1199 Gene3D G3DSA:3.40.50.300 2 163 4.6E-89 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS16150 51e6718e0582d09e489f49993efead09 1199 Gene3D G3DSA:3.40.50.300 1036 1184 4.6E-89 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS16150 51e6718e0582d09e489f49993efead09 1199 Hamap MF_01894 Chromosome partition protein Smc [smc]. 1 1189 22.122 T 06-07-2017 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 CAK77_RS16150 51e6718e0582d09e489f49993efead09 1199 SUPERFAMILY SSF52540 2 207 7.55E-69 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS16150 51e6718e0582d09e489f49993efead09 1199 SUPERFAMILY SSF52540 989 1182 7.55E-69 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS16150 51e6718e0582d09e489f49993efead09 1199 SUPERFAMILY SSF75553 463 669 1.96E-28 T 06-07-2017 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 CAK77_RS16380 88daa09f3ee2f4f5e7eca6d372249c1c 718 Gene3D G3DSA:3.30.870.10 537 716 2.4E-67 T 06-07-2017 CAK77_RS16380 88daa09f3ee2f4f5e7eca6d372249c1c 718 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 34 712 1.1E-247 T 06-07-2017 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 CAK77_RS16380 88daa09f3ee2f4f5e7eca6d372249c1c 718 SUPERFAMILY SSF56024 537 715 2.47E-63 T 06-07-2017 CAK77_RS16380 88daa09f3ee2f4f5e7eca6d372249c1c 718 SUPERFAMILY SSF56024 361 533 8.3E-57 T 06-07-2017 CAK77_RS16380 88daa09f3ee2f4f5e7eca6d372249c1c 718 Gene3D G3DSA:3.30.1840.10 137 334 9.7E-73 T 06-07-2017 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 CAK77_RS16380 88daa09f3ee2f4f5e7eca6d372249c1c 718 SUPERFAMILY SSF143724 138 345 2.16E-64 T 06-07-2017 CAK77_RS16380 88daa09f3ee2f4f5e7eca6d372249c1c 718 Pfam PF13089 Polyphosphate kinase N-terminal domain 35 140 4.3E-36 T 06-07-2017 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 CAK77_RS16380 88daa09f3ee2f4f5e7eca6d372249c1c 718 PIRSF PIRSF015589 16 718 2.2E-270 T 06-07-2017 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 CAK77_RS16380 88daa09f3ee2f4f5e7eca6d372249c1c 718 Pfam PF13090 Polyphosphate kinase C-terminal domain 366 711 1.7E-148 T 06-07-2017 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 CAK77_RS16380 88daa09f3ee2f4f5e7eca6d372249c1c 718 Gene3D G3DSA:3.30.870.10 348 536 7.1E-79 T 06-07-2017 CAK77_RS16380 88daa09f3ee2f4f5e7eca6d372249c1c 718 Pfam PF02503 Polyphosphate kinase middle domain 150 355 2.6E-69 T 06-07-2017 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 CAK77_RS16380 88daa09f3ee2f4f5e7eca6d372249c1c 718 Hamap MF_00347 Polyphosphate kinase [ppk]. 32 714 36.289 T 06-07-2017 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 CAK77_RS16380 88daa09f3ee2f4f5e7eca6d372249c1c 718 SUPERFAMILY SSF140356 32 136 3.79E-36 T 06-07-2017 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 CAK77_RS01055 a2a753b095cf1d4a91b5daa13f70f149 336 SMART SM01110 70 317 1.3E-54 T 06-07-2017 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 CAK77_RS01055 a2a753b095cf1d4a91b5daa13f70f149 336 Pfam PF01083 Cutinase 113 273 4.5E-13 T 06-07-2017 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 CAK77_RS01055 a2a753b095cf1d4a91b5daa13f70f149 336 SUPERFAMILY SSF53474 71 276 6.34E-28 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS01055 a2a753b095cf1d4a91b5daa13f70f149 336 Gene3D G3DSA:3.40.50.1820 253 328 4.0E-44 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS01055 a2a753b095cf1d4a91b5daa13f70f149 336 Gene3D G3DSA:3.40.50.1820 62 218 4.0E-44 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS13870 84fe55ae2cd0ff4c3202977b293ca60e 173 Hamap MF_00073 N utilization substance protein B homolog [nusB]. 26 161 22.013 T 06-07-2017 IPR011605 NusB antitermination factor GO:0006353 CAK77_RS13870 84fe55ae2cd0ff4c3202977b293ca60e 173 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 28 156 4.3E-39 T 06-07-2017 IPR011605 NusB antitermination factor GO:0006353 CAK77_RS13870 84fe55ae2cd0ff4c3202977b293ca60e 173 Pfam PF01029 NusB family 29 156 2.7E-34 T 06-07-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CAK77_RS13870 84fe55ae2cd0ff4c3202977b293ca60e 173 Gene3D G3DSA:1.10.940.10 25 156 2.1E-42 T 06-07-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CAK77_RS13870 84fe55ae2cd0ff4c3202977b293ca60e 173 SUPERFAMILY SSF48013 28 156 2.62E-38 T 06-07-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CAK77_RS18025 8313525615b3896111dd3c05a8f7ee0e 242 Pfam PF04138 GtrA-like protein 27 157 7.2E-22 T 06-07-2017 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 CAK77_RS04385 d25353a354da2c6f2fad7491c9ea91ae 159 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 65 78 - T 06-07-2017 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 CAK77_RS04385 d25353a354da2c6f2fad7491c9ea91ae 159 Gene3D G3DSA:3.40.980.10 8 155 1.5E-45 T 06-07-2017 IPR001453 MoaB/Mog domain CAK77_RS04385 d25353a354da2c6f2fad7491c9ea91ae 159 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 8 141 7.4E-29 T 06-07-2017 IPR001453 MoaB/Mog domain CAK77_RS04385 d25353a354da2c6f2fad7491c9ea91ae 159 SUPERFAMILY SSF53218 8 153 1.96E-36 T 06-07-2017 IPR001453 MoaB/Mog domain CAK77_RS04385 d25353a354da2c6f2fad7491c9ea91ae 159 SMART SM00852 9 149 9.5E-16 T 06-07-2017 IPR001453 MoaB/Mog domain CAK77_RS04385 d25353a354da2c6f2fad7491c9ea91ae 159 Pfam PF00994 Probable molybdopterin binding domain 10 143 2.5E-27 T 06-07-2017 IPR001453 MoaB/Mog domain CAK77_RS23355 6cf92b68df7105889947cb91bbaacec5 2713 Gene3D G3DSA:3.40.50.980 1264 1430 9.2E-43 T 06-07-2017 CAK77_RS23355 6cf92b68df7105889947cb91bbaacec5 2713 Gene3D G3DSA:3.40.50.980 190 356 2.6E-43 T 06-07-2017 CAK77_RS23355 6cf92b68df7105889947cb91bbaacec5 2713 Pfam PF13193 AMP-binding enzyme C-terminal domain 455 526 1.3E-7 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAK77_RS23355 6cf92b68df7105889947cb91bbaacec5 2713 Pfam PF13193 AMP-binding enzyme C-terminal domain 1528 1599 8.1E-10 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAK77_RS23355 6cf92b68df7105889947cb91bbaacec5 2713 Gene3D G3DSA:1.10.1200.10 555 617 1.7E-22 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS23355 6cf92b68df7105889947cb91bbaacec5 2713 Gene3D G3DSA:1.10.1200.10 2633 2711 6.6E-22 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS23355 6cf92b68df7105889947cb91bbaacec5 2713 Gene3D G3DSA:1.10.1200.10 1629 1691 4.0E-21 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS23355 6cf92b68df7105889947cb91bbaacec5 2713 SMART SM00823 Phosphopantetheine attachment site 551 620 4.2E-4 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAK77_RS23355 6cf92b68df7105889947cb91bbaacec5 2713 SMART SM00823 Phosphopantetheine attachment site 2642 2711 1.1E-6 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAK77_RS23355 6cf92b68df7105889947cb91bbaacec5 2713 SMART SM00823 Phosphopantetheine attachment site 1624 1692 0.81 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAK77_RS23355 6cf92b68df7105889947cb91bbaacec5 2713 SUPERFAMILY SSF52777 1885 2151 1.22E-21 T 06-07-2017 CAK77_RS23355 6cf92b68df7105889947cb91bbaacec5 2713 SUPERFAMILY SSF56801 1072 1637 3.92E-150 T 06-07-2017 CAK77_RS23355 6cf92b68df7105889947cb91bbaacec5 2713 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1255 1266 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK77_RS23355 6cf92b68df7105889947cb91bbaacec5 2713 SUPERFAMILY SSF47336 2635 2708 6.94E-18 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS23355 6cf92b68df7105889947cb91bbaacec5 2713 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1648 1663 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site CAK77_RS23355 6cf92b68df7105889947cb91bbaacec5 2713 SUPERFAMILY SSF47336 1616 1688 4.45E-15 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS23355 6cf92b68df7105889947cb91bbaacec5 2713 SUPERFAMILY SSF52777 637 812 1.22E-45 T 06-07-2017 CAK77_RS23355 6cf92b68df7105889947cb91bbaacec5 2713 SUPERFAMILY SSF52777 2363 2597 4.22E-53 T 06-07-2017 CAK77_RS23355 6cf92b68df7105889947cb91bbaacec5 2713 Pfam PF00668 Condensation domain 634 936 3.0E-63 T 06-07-2017 IPR001242 Condensation domain CAK77_RS23355 6cf92b68df7105889947cb91bbaacec5 2713 Pfam PF00668 Condensation domain 2181 2473 2.5E-54 T 06-07-2017 IPR001242 Condensation domain CAK77_RS23355 6cf92b68df7105889947cb91bbaacec5 2713 Pfam PF00668 Condensation domain 1723 2002 5.5E-18 T 06-07-2017 IPR001242 Condensation domain CAK77_RS23355 6cf92b68df7105889947cb91bbaacec5 2713 ProSitePatterns PS00012 Phosphopantetheine attachment site. 575 590 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site CAK77_RS23355 6cf92b68df7105889947cb91bbaacec5 2713 ProSitePatterns PS00455 Putative AMP-binding domain signature. 185 196 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK77_RS23355 6cf92b68df7105889947cb91bbaacec5 2713 Pfam PF13745 HxxPF-repeated domain 958 1059 2.7E-26 T 06-07-2017 CAK77_RS23355 6cf92b68df7105889947cb91bbaacec5 2713 Gene3D G3DSA:3.40.50.980 40 189 2.4E-46 T 06-07-2017 CAK77_RS23355 6cf92b68df7105889947cb91bbaacec5 2713 SUPERFAMILY SSF56801 34 564 6.41E-141 T 06-07-2017 CAK77_RS23355 6cf92b68df7105889947cb91bbaacec5 2713 SUPERFAMILY SSF47336 543 613 1.83E-18 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS23355 6cf92b68df7105889947cb91bbaacec5 2713 Pfam PF00550 Phosphopantetheine attachment site 2645 2706 2.0E-13 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS23355 6cf92b68df7105889947cb91bbaacec5 2713 Pfam PF00550 Phosphopantetheine attachment site 554 613 2.8E-11 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS23355 6cf92b68df7105889947cb91bbaacec5 2713 Pfam PF00550 Phosphopantetheine attachment site 1627 1687 7.8E-7 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS23355 6cf92b68df7105889947cb91bbaacec5 2713 Pfam PF00501 AMP-binding enzyme 1115 1520 7.0E-89 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK77_RS23355 6cf92b68df7105889947cb91bbaacec5 2713 Pfam PF00501 AMP-binding enzyme 45 447 4.8E-87 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK77_RS23355 6cf92b68df7105889947cb91bbaacec5 2713 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2666 2681 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site CAK77_RS23355 6cf92b68df7105889947cb91bbaacec5 2713 SUPERFAMILY SSF52777 1707 1867 6.0E-25 T 06-07-2017 CAK77_RS23355 6cf92b68df7105889947cb91bbaacec5 2713 Gene3D G3DSA:3.30.300.30 442 554 5.3E-36 T 06-07-2017 CAK77_RS23355 6cf92b68df7105889947cb91bbaacec5 2713 Gene3D G3DSA:3.30.300.30 1515 1628 3.1E-39 T 06-07-2017 CAK77_RS23355 6cf92b68df7105889947cb91bbaacec5 2713 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1136 1544 2.2E-131 T 06-07-2017 IPR010071 Amino acid adenylation domain CAK77_RS23355 6cf92b68df7105889947cb91bbaacec5 2713 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 66 471 2.5E-129 T 06-07-2017 IPR010071 Amino acid adenylation domain CAK77_RS23355 6cf92b68df7105889947cb91bbaacec5 2713 SUPERFAMILY SSF52777 823 1077 2.78E-55 T 06-07-2017 CAK77_RS23355 6cf92b68df7105889947cb91bbaacec5 2713 Gene3D G3DSA:3.40.50.980 1110 1263 1.0E-45 T 06-07-2017 CAK77_RS23355 6cf92b68df7105889947cb91bbaacec5 2713 SUPERFAMILY SSF52777 2179 2375 6.3E-40 T 06-07-2017 CAK77_RS23355 6cf92b68df7105889947cb91bbaacec5 2713 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 2017 2173 1.4E-33 T 06-07-2017 IPR010060 Non-ribosomal peptide synthase CAK77_RS23355 6cf92b68df7105889947cb91bbaacec5 2713 Gene3D G3DSA:2.30.38.10 1431 1509 2.2E-21 T 06-07-2017 CAK77_RS23355 6cf92b68df7105889947cb91bbaacec5 2713 Gene3D G3DSA:2.30.38.10 357 437 1.8E-17 T 06-07-2017 CAK77_RS17800 249d0d77b4965d341504b8d8dcf39ea0 929 SUPERFAMILY SSF81886 614 830 3.53E-74 T 06-07-2017 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CAK77_RS17800 249d0d77b4965d341504b8d8dcf39ea0 929 PRINTS PR00906 SecA protein signature 59 83 1.1E-70 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CAK77_RS17800 249d0d77b4965d341504b8d8dcf39ea0 929 PRINTS PR00906 SecA protein signature 97 111 1.1E-70 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CAK77_RS17800 249d0d77b4965d341504b8d8dcf39ea0 929 PRINTS PR00906 SecA protein signature 317 339 1.1E-70 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CAK77_RS17800 249d0d77b4965d341504b8d8dcf39ea0 929 PRINTS PR00906 SecA protein signature 113 123 1.1E-70 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CAK77_RS17800 249d0d77b4965d341504b8d8dcf39ea0 929 PRINTS PR00906 SecA protein signature 391 404 1.1E-70 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CAK77_RS17800 249d0d77b4965d341504b8d8dcf39ea0 929 PRINTS PR00906 SecA protein signature 354 371 1.1E-70 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CAK77_RS17800 249d0d77b4965d341504b8d8dcf39ea0 929 PRINTS PR00906 SecA protein signature 166 186 1.1E-70 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CAK77_RS17800 249d0d77b4965d341504b8d8dcf39ea0 929 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 24 817 0.0 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CAK77_RS17800 249d0d77b4965d341504b8d8dcf39ea0 929 Gene3D G3DSA:3.40.50.300 395 612 5.3E-93 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS17800 249d0d77b4965d341504b8d8dcf39ea0 929 Gene3D G3DSA:3.90.1440.10 228 346 1.1E-46 T 06-07-2017 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CAK77_RS17800 249d0d77b4965d341504b8d8dcf39ea0 929 SMART SM00958 224 336 3.3E-60 T 06-07-2017 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CAK77_RS17800 249d0d77b4965d341504b8d8dcf39ea0 929 Hamap MF_01382 Protein translocase subunit SecA [secA]. 1 833 19.759 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CAK77_RS17800 249d0d77b4965d341504b8d8dcf39ea0 929 Gene3D G3DSA:3.40.50.300 347 394 5.5E-122 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS17800 249d0d77b4965d341504b8d8dcf39ea0 929 Gene3D G3DSA:3.40.50.300 2 224 5.5E-122 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS17800 249d0d77b4965d341504b8d8dcf39ea0 929 SUPERFAMILY SSF52540 4 224 3.39E-78 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS17800 249d0d77b4965d341504b8d8dcf39ea0 929 SUPERFAMILY SSF52540 346 393 3.39E-78 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS17800 249d0d77b4965d341504b8d8dcf39ea0 929 Pfam PF07516 SecA Wing and Scaffold domain 610 830 8.3E-69 T 06-07-2017 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CAK77_RS17800 249d0d77b4965d341504b8d8dcf39ea0 929 SUPERFAMILY SSF52540 394 611 1.02E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS17800 249d0d77b4965d341504b8d8dcf39ea0 929 Pfam PF07517 SecA DEAD-like domain 6 380 3.4E-127 T 06-07-2017 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 CAK77_RS17800 249d0d77b4965d341504b8d8dcf39ea0 929 SUPERFAMILY SSF81767 223 346 1.7E-42 T 06-07-2017 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CAK77_RS17800 249d0d77b4965d341504b8d8dcf39ea0 929 Gene3D G3DSA:1.10.3060.10 641 831 9.4E-62 T 06-07-2017 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CAK77_RS17800 249d0d77b4965d341504b8d8dcf39ea0 929 SMART SM00957 2 380 2.0E-272 T 06-07-2017 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 CAK77_RS17800 249d0d77b4965d341504b8d8dcf39ea0 929 Pfam PF01043 SecA preprotein cross-linking domain 229 336 1.8E-34 T 06-07-2017 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CAK77_RS17800 249d0d77b4965d341504b8d8dcf39ea0 929 ProSitePatterns PS01312 SecA family signature. 478 493 - T 06-07-2017 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 CAK77_RS19015 78960ef3f7e7a59a6974369044300304 286 Pfam PF12697 Alpha/beta hydrolase family 33 276 8.3E-20 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS19015 78960ef3f7e7a59a6974369044300304 286 Gene3D G3DSA:3.40.50.1820 5 285 2.5E-59 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS19015 78960ef3f7e7a59a6974369044300304 286 PRINTS PR00111 Alpha/beta hydrolase fold signature 102 115 1.3E-17 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS19015 78960ef3f7e7a59a6974369044300304 286 PRINTS PR00111 Alpha/beta hydrolase fold signature 116 129 1.3E-17 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS19015 78960ef3f7e7a59a6974369044300304 286 PRINTS PR00111 Alpha/beta hydrolase fold signature 59 74 1.3E-17 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS19015 78960ef3f7e7a59a6974369044300304 286 PRINTS PR00111 Alpha/beta hydrolase fold signature 230 244 1.3E-17 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS19015 78960ef3f7e7a59a6974369044300304 286 PRINTS PR00412 Epoxide hydrolase signature 261 283 2.3E-5 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK77_RS19015 78960ef3f7e7a59a6974369044300304 286 PRINTS PR00412 Epoxide hydrolase signature 59 74 2.3E-5 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK77_RS19015 78960ef3f7e7a59a6974369044300304 286 PRINTS PR00412 Epoxide hydrolase signature 116 129 2.3E-5 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK77_RS19015 78960ef3f7e7a59a6974369044300304 286 PRINTS PR00412 Epoxide hydrolase signature 102 115 2.3E-5 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK77_RS19015 78960ef3f7e7a59a6974369044300304 286 SUPERFAMILY SSF53474 12 285 8.4E-60 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS17625 34f29daf0410d9163763f65ac15c0e91 232 SUPERFAMILY SSF53800 4 216 3.71E-28 T 06-07-2017 CAK77_RS17625 34f29daf0410d9163763f65ac15c0e91 232 Pfam PF01903 CbiX 123 212 4.6E-7 T 06-07-2017 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 CAK77_RS17625 34f29daf0410d9163763f65ac15c0e91 232 Pfam PF01903 CbiX 9 102 1.4E-12 T 06-07-2017 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 CAK77_RS17625 34f29daf0410d9163763f65ac15c0e91 232 Gene3D G3DSA:3.40.50.1400 3 112 5.0E-22 T 06-07-2017 CAK77_RS17625 34f29daf0410d9163763f65ac15c0e91 232 Gene3D G3DSA:3.40.50.1400 115 222 8.7E-21 T 06-07-2017 CAK77_RS15625 72a393ec11710f4d5a4c3fd11bbd6026 505 Gene3D G3DSA:1.20.1250.20 272 483 4.8E-11 T 06-07-2017 CAK77_RS15625 72a393ec11710f4d5a4c3fd11bbd6026 505 Gene3D G3DSA:1.20.1250.20 24 205 5.1E-27 T 06-07-2017 CAK77_RS15625 72a393ec11710f4d5a4c3fd11bbd6026 505 Pfam PF07690 Major Facilitator Superfamily 31 419 2.2E-42 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK77_RS15625 72a393ec11710f4d5a4c3fd11bbd6026 505 SUPERFAMILY SSF103473 258 479 2.09E-53 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK77_RS15625 72a393ec11710f4d5a4c3fd11bbd6026 505 SUPERFAMILY SSF103473 14 208 2.09E-53 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK77_RS16360 996543278979abdfd5ecb66fab10ffa4 381 Pfam PF01820 D-ala D-ala ligase N-terminus 16 146 3.8E-33 T 06-07-2017 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK77_RS16360 996543278979abdfd5ecb66fab10ffa4 381 PIRSF PIRSF039102 12 379 6.9E-107 T 06-07-2017 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK77_RS16360 996543278979abdfd5ecb66fab10ffa4 381 SUPERFAMILY SSF56059 156 374 2.47E-53 T 06-07-2017 CAK77_RS16360 996543278979abdfd5ecb66fab10ffa4 381 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 15 374 40.903 T 06-07-2017 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK77_RS16360 996543278979abdfd5ecb66fab10ffa4 381 Gene3D G3DSA:3.30.470.20 147 172 5.4E-46 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAK77_RS16360 996543278979abdfd5ecb66fab10ffa4 381 Gene3D G3DSA:3.30.470.20 240 374 5.4E-46 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAK77_RS16360 996543278979abdfd5ecb66fab10ffa4 381 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 16 373 1.3E-107 T 06-07-2017 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK77_RS16360 996543278979abdfd5ecb66fab10ffa4 381 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 123 134 - T 06-07-2017 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK77_RS16360 996543278979abdfd5ecb66fab10ffa4 381 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 317 344 - T 06-07-2017 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK77_RS16360 996543278979abdfd5ecb66fab10ffa4 381 Gene3D G3DSA:3.30.1490.20 182 236 3.1E-22 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CAK77_RS16360 996543278979abdfd5ecb66fab10ffa4 381 Gene3D G3DSA:3.40.50.20 13 145 1.4E-36 T 06-07-2017 IPR016185 Pre-ATP-grasp domain CAK77_RS16360 996543278979abdfd5ecb66fab10ffa4 381 Pfam PF07478 D-ala D-ala ligase C-terminus 163 370 3.7E-69 T 06-07-2017 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK77_RS16360 996543278979abdfd5ecb66fab10ffa4 381 SUPERFAMILY SSF52440 14 155 6.71E-35 T 06-07-2017 IPR016185 Pre-ATP-grasp domain CAK77_RS00345 7afc11af7f7c467e21e9618f7d2fcfd3 501 SMART SM00331 11 235 1.5E-46 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAK77_RS00345 7afc11af7f7c467e21e9618f7d2fcfd3 501 SUPERFAMILY SSF81606 4 234 3.53E-65 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAK77_RS00345 7afc11af7f7c467e21e9618f7d2fcfd3 501 Pfam PF13672 Protein phosphatase 2C 18 198 3.2E-12 T 06-07-2017 CAK77_RS00345 7afc11af7f7c467e21e9618f7d2fcfd3 501 SMART SM00332 2 233 1.5E-27 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAK77_RS00345 7afc11af7f7c467e21e9618f7d2fcfd3 501 Gene3D G3DSA:3.60.40.10 3 235 5.1E-68 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAK77_RS19990 ef74993f6c8ae5edacb26c2a053c98f4 549 Pfam PF02602 Uroporphyrinogen-III synthase HemD 293 523 3.7E-63 T 06-07-2017 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAK77_RS19990 ef74993f6c8ae5edacb26c2a053c98f4 549 Gene3D G3DSA:3.30.950.10 150 284 1.4E-26 T 06-07-2017 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAK77_RS19990 ef74993f6c8ae5edacb26c2a053c98f4 549 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 14 28 - T 06-07-2017 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CAK77_RS19990 ef74993f6c8ae5edacb26c2a053c98f4 549 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 10 236 1.2E-39 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAK77_RS19990 ef74993f6c8ae5edacb26c2a053c98f4 549 SUPERFAMILY SSF69618 279 530 1.44E-68 T 06-07-2017 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAK77_RS19990 ef74993f6c8ae5edacb26c2a053c98f4 549 Gene3D G3DSA:3.40.1010.10 7 64 1.8E-32 T 06-07-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAK77_RS19990 ef74993f6c8ae5edacb26c2a053c98f4 549 Gene3D G3DSA:3.40.1010.10 97 149 1.8E-32 T 06-07-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAK77_RS19990 ef74993f6c8ae5edacb26c2a053c98f4 549 SUPERFAMILY SSF53790 6 282 2.38E-41 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAK77_RS19990 ef74993f6c8ae5edacb26c2a053c98f4 549 Gene3D G3DSA:3.40.50.10090 285 406 5.5E-38 T 06-07-2017 CAK77_RS19990 ef74993f6c8ae5edacb26c2a053c98f4 549 Gene3D G3DSA:3.40.50.10090 414 530 2.3E-34 T 06-07-2017 CAK77_RS16310 03ba4b93eeff7686a1944ec42536efff 266 Pfam PF12680 SnoaL-like domain 66 110 2.7E-6 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain CAK77_RS16310 03ba4b93eeff7686a1944ec42536efff 266 Gene3D G3DSA:3.10.450.50 60 187 3.0E-6 T 06-07-2017 IPR032710 NTF2-like domain CAK77_RS16310 03ba4b93eeff7686a1944ec42536efff 266 SUPERFAMILY SSF54427 60 188 1.76E-9 T 06-07-2017 IPR032710 NTF2-like domain CAK77_RS07440 3019cb316949627e350d53e10eaeebe6 90 SUPERFAMILY SSF54285 1 90 1.42E-25 T 06-07-2017 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp CAK77_RS07440 3019cb316949627e350d53e10eaeebe6 90 Gene3D G3DSA:3.10.20.30 3 88 1.5E-29 T 06-07-2017 IPR012675 Beta-grasp domain CAK77_RS07440 3019cb316949627e350d53e10eaeebe6 90 Pfam PF02597 ThiS family 6 90 4.0E-19 T 06-07-2017 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 CAK77_RS02295 0a91d7595af1fd2f2fcf6ca916187148 261 Gene3D G3DSA:3.60.15.10 22 221 2.2E-44 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK77_RS02295 0a91d7595af1fd2f2fcf6ca916187148 261 SUPERFAMILY SSF56281 9 259 2.8E-49 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK77_RS02295 0a91d7595af1fd2f2fcf6ca916187148 261 Pfam PF00753 Metallo-beta-lactamase superfamily 28 190 2.2E-14 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK77_RS02295 0a91d7595af1fd2f2fcf6ca916187148 261 SMART SM00849 30 190 8.0E-28 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK77_RS10015 48ebc7e857f1c7c5a1aeb24cb9cfd862 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 9 22 7.0E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS10015 48ebc7e857f1c7c5a1aeb24cb9cfd862 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 53 7.0E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS10015 48ebc7e857f1c7c5a1aeb24cb9cfd862 197 SUPERFAMILY SSF48498 75 152 1.89E-6 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS10015 48ebc7e857f1c7c5a1aeb24cb9cfd862 197 Gene3D G3DSA:1.10.357.10 56 159 1.2E-17 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS10015 48ebc7e857f1c7c5a1aeb24cb9cfd862 197 Gene3D G3DSA:1.10.10.60 4 55 2.4E-21 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS10015 48ebc7e857f1c7c5a1aeb24cb9cfd862 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 55 2.4E-18 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS10015 48ebc7e857f1c7c5a1aeb24cb9cfd862 197 SUPERFAMILY SSF46689 3 70 4.41E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS22990 e56406d9cf43b0cbd6dadf08955c8df7 373 TIGRFAM TIGR01800 cit_synth_II: 2-methylcitrate synthase/citrate synthase II 10 370 5.4E-141 T 06-07-2017 IPR011278 2-methylcitrate synthase/citrate synthase type I GO:0005737|GO:0046912 CAK77_RS22990 e56406d9cf43b0cbd6dadf08955c8df7 373 Gene3D G3DSA:1.10.230.10 239 324 1.6E-26 T 06-07-2017 IPR016143 Citrate synthase-like, small alpha subdomain Reactome: R-HSA-163765|Reactome: R-HSA-75105 CAK77_RS22990 e56406d9cf43b0cbd6dadf08955c8df7 373 SUPERFAMILY SSF48256 6 369 1.7E-120 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 CAK77_RS22990 e56406d9cf43b0cbd6dadf08955c8df7 373 Pfam PF00285 Citrate synthase, C-terminal domain 11 359 2.4E-115 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 CAK77_RS22990 e56406d9cf43b0cbd6dadf08955c8df7 373 PIRSF PIRSF001369 3 373 5.5E-120 T 06-07-2017 IPR024176 Citrate synthase, bacterial-type CAK77_RS22990 e56406d9cf43b0cbd6dadf08955c8df7 373 Gene3D G3DSA:1.10.580.10 19 238 1.3E-79 T 06-07-2017 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 CAK77_RS22990 e56406d9cf43b0cbd6dadf08955c8df7 373 ProSitePatterns PS00480 Citrate synthase signature. 260 272 - T 06-07-2017 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 CAK77_RS22990 e56406d9cf43b0cbd6dadf08955c8df7 373 PRINTS PR00143 Citrate synthase signature 330 344 1.6E-36 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 CAK77_RS22990 e56406d9cf43b0cbd6dadf08955c8df7 373 PRINTS PR00143 Citrate synthase signature 178 193 1.6E-36 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 CAK77_RS22990 e56406d9cf43b0cbd6dadf08955c8df7 373 PRINTS PR00143 Citrate synthase signature 253 273 1.6E-36 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 CAK77_RS22990 e56406d9cf43b0cbd6dadf08955c8df7 373 PRINTS PR00143 Citrate synthase signature 200 228 1.6E-36 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 CAK77_RS22990 e56406d9cf43b0cbd6dadf08955c8df7 373 PRINTS PR00143 Citrate synthase signature 310 326 1.6E-36 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 CAK77_RS22990 e56406d9cf43b0cbd6dadf08955c8df7 373 PRINTS PR00143 Citrate synthase signature 129 142 1.6E-36 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 CAK77_RS12325 c1c8233778770c120faa611782941ec7 231 PIRSF PIRSF036625 1 230 1.4E-62 T 06-07-2017 IPR012074 GAF-ANTAR transcription anti-termination regulator, putative CAK77_RS12325 c1c8233778770c120faa611782941ec7 231 SMART SM01012 170 225 5.5E-21 T 06-07-2017 IPR005561 ANTAR domain GO:0003723 CAK77_RS12325 c1c8233778770c120faa611782941ec7 231 SUPERFAMILY SSF52172 168 225 2.68E-9 T 06-07-2017 IPR011006 CheY-like superfamily CAK77_RS12325 c1c8233778770c120faa611782941ec7 231 Gene3D G3DSA:3.30.450.40 14 175 4.1E-16 T 06-07-2017 IPR029016 GAF domain-like CAK77_RS12325 c1c8233778770c120faa611782941ec7 231 Gene3D G3DSA:1.10.10.10 176 227 1.6E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS12325 c1c8233778770c120faa611782941ec7 231 Pfam PF13185 GAF domain 26 165 3.9E-10 T 06-07-2017 IPR003018 GAF domain GO:0005515 CAK77_RS12325 c1c8233778770c120faa611782941ec7 231 SUPERFAMILY SSF55781 31 173 9.32E-17 T 06-07-2017 IPR029016 GAF domain-like CAK77_RS12325 c1c8233778770c120faa611782941ec7 231 Pfam PF03861 ANTAR domain 175 225 3.0E-19 T 06-07-2017 IPR005561 ANTAR domain GO:0003723 CAK77_RS19955 fe37aab84563421c6bc389ed18ffc34d 723 Pfam PF00122 E1-E2 ATPase 206 425 3.5E-62 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 CAK77_RS19955 fe37aab84563421c6bc389ed18ffc34d 723 Pfam PF00702 haloacid dehalogenase-like hydrolase 430 631 1.4E-40 T 06-07-2017 CAK77_RS19955 fe37aab84563421c6bc389ed18ffc34d 723 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 204 720 3.3E-116 T 06-07-2017 CAK77_RS19955 fe37aab84563421c6bc389ed18ffc34d 723 SUPERFAMILY SSF81653 240 334 1.44E-23 T 06-07-2017 CAK77_RS19955 fe37aab84563421c6bc389ed18ffc34d 723 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 167 719 6.2E-170 T 06-07-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CAK77_RS19955 fe37aab84563421c6bc389ed18ffc34d 723 PRINTS PR00943 Copper-transporting ATPase signature 204 223 1.1E-10 T 06-07-2017 CAK77_RS19955 fe37aab84563421c6bc389ed18ffc34d 723 PRINTS PR00943 Copper-transporting ATPase signature 52 72 1.1E-10 T 06-07-2017 CAK77_RS19955 fe37aab84563421c6bc389ed18ffc34d 723 PRINTS PR00943 Copper-transporting ATPase signature 594 611 1.1E-10 T 06-07-2017 CAK77_RS19955 fe37aab84563421c6bc389ed18ffc34d 723 PRINTS PR00943 Copper-transporting ATPase signature 357 371 1.1E-10 T 06-07-2017 CAK77_RS19955 fe37aab84563421c6bc389ed18ffc34d 723 PRINTS PR00943 Copper-transporting ATPase signature 417 432 1.1E-10 T 06-07-2017 CAK77_RS19955 fe37aab84563421c6bc389ed18ffc34d 723 PRINTS PR00943 Copper-transporting ATPase signature 651 665 1.1E-10 T 06-07-2017 CAK77_RS19955 fe37aab84563421c6bc389ed18ffc34d 723 ProSitePatterns PS01047 Heavy-metal-associated domain. 15 43 - T 06-07-2017 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 CAK77_RS19955 fe37aab84563421c6bc389ed18ffc34d 723 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 434 448 1.2E-22 T 06-07-2017 CAK77_RS19955 fe37aab84563421c6bc389ed18ffc34d 723 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 562 572 1.2E-22 T 06-07-2017 CAK77_RS19955 fe37aab84563421c6bc389ed18ffc34d 723 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 617 636 1.2E-22 T 06-07-2017 CAK77_RS19955 fe37aab84563421c6bc389ed18ffc34d 723 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 284 298 1.2E-22 T 06-07-2017 CAK77_RS19955 fe37aab84563421c6bc389ed18ffc34d 723 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 640 652 1.2E-22 T 06-07-2017 CAK77_RS19955 fe37aab84563421c6bc389ed18ffc34d 723 SUPERFAMILY SSF55008 5 76 4.84E-18 T 06-07-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CAK77_RS19955 fe37aab84563421c6bc389ed18ffc34d 723 Pfam PF00403 Heavy-metal-associated domain 13 71 1.7E-11 T 06-07-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CAK77_RS19955 fe37aab84563421c6bc389ed18ffc34d 723 ProSitePatterns PS01229 Hypothetical cof family signature 2. 617 639 - T 06-07-2017 CAK77_RS19955 fe37aab84563421c6bc389ed18ffc34d 723 Gene3D G3DSA:3.40.1110.10 460 559 6.7E-12 T 06-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CAK77_RS19955 fe37aab84563421c6bc389ed18ffc34d 723 SUPERFAMILY SSF56784 432 717 9.07E-53 T 06-07-2017 IPR023214 HAD-like domain CAK77_RS19955 fe37aab84563421c6bc389ed18ffc34d 723 Gene3D G3DSA:3.30.70.100 5 74 7.5E-23 T 06-07-2017 CAK77_RS19955 fe37aab84563421c6bc389ed18ffc34d 723 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 149 720 6.0E-162 T 06-07-2017 CAK77_RS19955 fe37aab84563421c6bc389ed18ffc34d 723 Gene3D G3DSA:3.40.50.1000 417 448 2.4E-43 T 06-07-2017 IPR023214 HAD-like domain CAK77_RS19955 fe37aab84563421c6bc389ed18ffc34d 723 Gene3D G3DSA:3.40.50.1000 560 663 2.4E-43 T 06-07-2017 IPR023214 HAD-like domain CAK77_RS19955 fe37aab84563421c6bc389ed18ffc34d 723 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 208 699 1.9E-80 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CAK77_RS19955 fe37aab84563421c6bc389ed18ffc34d 723 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 436 442 - T 06-07-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CAK77_RS19955 fe37aab84563421c6bc389ed18ffc34d 723 Gene3D G3DSA:2.70.150.10 167 335 2.4E-25 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 CAK77_RS19955 fe37aab84563421c6bc389ed18ffc34d 723 SUPERFAMILY SSF81665 666 696 1.44E-14 T 06-07-2017 CAK77_RS19955 fe37aab84563421c6bc389ed18ffc34d 723 SUPERFAMILY SSF81665 335 428 1.44E-14 T 06-07-2017 CAK77_RS19955 fe37aab84563421c6bc389ed18ffc34d 723 SUPERFAMILY SSF81665 176 235 1.44E-14 T 06-07-2017 CAK77_RS04185 c9dce0fff4cabaa301f55e12171ce570 397 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 243 390 3.6E-27 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS04185 c9dce0fff4cabaa301f55e12171ce570 397 Gene3D G3DSA:1.10.540.10 17 137 2.6E-36 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS04185 c9dce0fff4cabaa301f55e12171ce570 397 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 141 231 2.7E-21 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAK77_RS04185 c9dce0fff4cabaa301f55e12171ce570 397 Gene3D G3DSA:1.20.140.10 246 394 1.2E-34 T 06-07-2017 CAK77_RS04185 c9dce0fff4cabaa301f55e12171ce570 397 Gene3D G3DSA:2.40.110.10 140 239 1.6E-33 T 06-07-2017 CAK77_RS04185 c9dce0fff4cabaa301f55e12171ce570 397 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 27 136 1.6E-27 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS04185 c9dce0fff4cabaa301f55e12171ce570 397 SUPERFAMILY SSF47203 248 393 1.61E-33 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS04185 c9dce0fff4cabaa301f55e12171ce570 397 SUPERFAMILY SSF56645 17 241 2.88E-69 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK77_RS20150 5d1dc017489e23b55f3552197f9ecbd2 317 SUPERFAMILY SSF51735 6 278 8.21E-70 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS20150 5d1dc017489e23b55f3552197f9ecbd2 317 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 2.6E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS20150 5d1dc017489e23b55f3552197f9ecbd2 317 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 2.6E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS20150 5d1dc017489e23b55f3552197f9ecbd2 317 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 2.6E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS20150 5d1dc017489e23b55f3552197f9ecbd2 317 Pfam PF00106 short chain dehydrogenase 11 195 4.9E-57 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS20150 5d1dc017489e23b55f3552197f9ecbd2 317 Gene3D G3DSA:3.40.50.720 10 264 7.8E-73 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS20150 5d1dc017489e23b55f3552197f9ecbd2 317 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK77_RS20150 5d1dc017489e23b55f3552197f9ecbd2 317 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 1.4E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS20150 5d1dc017489e23b55f3552197f9ecbd2 317 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 1.4E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS20150 5d1dc017489e23b55f3552197f9ecbd2 317 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 1.4E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS20150 5d1dc017489e23b55f3552197f9ecbd2 317 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 1.4E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS20150 5d1dc017489e23b55f3552197f9ecbd2 317 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 1.4E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS23400 5fa4ad77f62d6d12f5dafeb0e228db0d 318 SUPERFAMILY SSF52540 97 213 4.91E-16 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS23400 5fa4ad77f62d6d12f5dafeb0e228db0d 318 SUPERFAMILY SSF52540 8 54 4.91E-16 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS23400 5fa4ad77f62d6d12f5dafeb0e228db0d 318 Gene3D G3DSA:3.40.50.300 13 33 5.4E-4 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS23400 5fa4ad77f62d6d12f5dafeb0e228db0d 318 Gene3D G3DSA:3.40.50.300 86 218 5.4E-4 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS04235 ca2b0c953a19914ad1ad41c3060ed384 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 1.2E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS04235 ca2b0c953a19914ad1ad41c3060ed384 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 1.2E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS04235 ca2b0c953a19914ad1ad41c3060ed384 214 Gene3D G3DSA:1.10.357.10 11 207 1.0E-32 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS04235 ca2b0c953a19914ad1ad41c3060ed384 214 SUPERFAMILY SSF46689 12 84 1.95E-19 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS04235 ca2b0c953a19914ad1ad41c3060ed384 214 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 66 1.7E-16 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS19170 87158bbf07e24645e622435dbf64ed67 414 TIGRFAM TIGR01885 Orn_aminotrans: ornithine--oxo-acid transaminase 17 410 1.1E-143 T 06-07-2017 IPR010164 Ornithine aminotransferase GO:0008483|GO:0030170 KEGG: 00330+2.6.1.13|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CAK77_RS19170 87158bbf07e24645e622435dbf64ed67 414 SUPERFAMILY SSF53383 14 411 1.18E-111 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK77_RS19170 87158bbf07e24645e622435dbf64ed67 414 Gene3D G3DSA:3.90.1150.10 320 411 3.1E-35 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK77_RS19170 87158bbf07e24645e622435dbf64ed67 414 Gene3D G3DSA:3.90.1150.10 15 70 3.1E-35 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK77_RS19170 87158bbf07e24645e622435dbf64ed67 414 Gene3D G3DSA:3.40.640.10 71 317 1.5E-77 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK77_RS19170 87158bbf07e24645e622435dbf64ed67 414 Pfam PF00202 Aminotransferase class-III 27 410 2.2E-107 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAK77_RS19170 87158bbf07e24645e622435dbf64ed67 414 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 235 272 - T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAK77_RS22575 b4492d14f96b56c98d4100f153cf6fc4 660 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 557 568 4.5E-23 T 06-07-2017 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 CAK77_RS22575 b4492d14f96b56c98d4100f153cf6fc4 660 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 484 500 4.5E-23 T 06-07-2017 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 CAK77_RS22575 b4492d14f96b56c98d4100f153cf6fc4 660 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 445 457 4.5E-23 T 06-07-2017 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 CAK77_RS22575 b4492d14f96b56c98d4100f153cf6fc4 660 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 463 475 4.5E-23 T 06-07-2017 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 CAK77_RS22575 b4492d14f96b56c98d4100f153cf6fc4 660 SUPERFAMILY SSF55486 8 659 6.35E-208 T 06-07-2017 CAK77_RS22575 b4492d14f96b56c98d4100f153cf6fc4 660 Gene3D G3DSA:3.40.390.10 444 659 6.3E-107 T 06-07-2017 IPR024079 Metallopeptidase, catalytic domain GO:0008237 CAK77_RS22575 b4492d14f96b56c98d4100f153cf6fc4 660 Gene3D G3DSA:3.40.390.10 284 404 6.3E-107 T 06-07-2017 IPR024079 Metallopeptidase, catalytic domain GO:0008237 CAK77_RS22575 b4492d14f96b56c98d4100f153cf6fc4 660 Pfam PF05649 Peptidase family M13 23 401 2.9E-101 T 06-07-2017 IPR008753 Peptidase M13, N-terminal domain GO:0006508 CAK77_RS22575 b4492d14f96b56c98d4100f153cf6fc4 660 Pfam PF01431 Peptidase family M13 453 656 6.8E-75 T 06-07-2017 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 CAK77_RS15460 8130c4f506cc7d7ec01e6037cbd0abda 755 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 14 736 27.095 T 06-07-2017 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CAK77_RS15460 8130c4f506cc7d7ec01e6037cbd0abda 755 SUPERFAMILY SSF55666 482 586 6.78E-23 T 06-07-2017 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CAK77_RS15460 8130c4f506cc7d7ec01e6037cbd0abda 755 SUPERFAMILY SSF54791 594 681 9.7E-19 T 06-07-2017 IPR004088 K Homology domain, type 1 GO:0003723 CAK77_RS15460 8130c4f506cc7d7ec01e6037cbd0abda 755 PIRSF PIRSF005499 12 754 4.1E-289 T 06-07-2017 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CAK77_RS15460 8130c4f506cc7d7ec01e6037cbd0abda 755 SUPERFAMILY SSF55666 157 268 2.5E-26 T 06-07-2017 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CAK77_RS15460 8130c4f506cc7d7ec01e6037cbd0abda 755 SMART SM00322 592 657 3.0E-13 T 06-07-2017 IPR004087 K Homology domain GO:0003676 CAK77_RS15460 8130c4f506cc7d7ec01e6037cbd0abda 755 SUPERFAMILY SSF54211 328 500 1.42E-44 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAK77_RS15460 8130c4f506cc7d7ec01e6037cbd0abda 755 TIGRFAM TIGR02696 pppGpp_PNP: guanosine pentaphosphate synthetase I/polyribonucleotide nucleotidyltransferase 10 732 0.0 T 06-07-2017 IPR014069 Guanosine pentaphosphate synthetase I/polyribonucleotide nucleotidyltransferase GO:0004654|GO:0005737|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CAK77_RS15460 8130c4f506cc7d7ec01e6037cbd0abda 755 Gene3D G3DSA:3.30.1370.10 591 662 1.1E-22 T 06-07-2017 IPR004088 K Homology domain, type 1 GO:0003723 CAK77_RS15460 8130c4f506cc7d7ec01e6037cbd0abda 755 Gene3D G3DSA:2.40.50.140 663 730 5.8E-19 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS15460 8130c4f506cc7d7ec01e6037cbd0abda 755 SUPERFAMILY SSF46915 272 352 4.45E-18 T 06-07-2017 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CAK77_RS15460 8130c4f506cc7d7ec01e6037cbd0abda 755 SMART SM00316 662 733 1.9E-17 T 06-07-2017 IPR022967 RNA-binding domain, S1 CAK77_RS15460 8130c4f506cc7d7ec01e6037cbd0abda 755 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 22 730 3.4E-266 T 06-07-2017 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CAK77_RS15460 8130c4f506cc7d7ec01e6037cbd0abda 755 SUPERFAMILY SSF54211 13 156 6.58E-45 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAK77_RS15460 8130c4f506cc7d7ec01e6037cbd0abda 755 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 275 351 4.1E-20 T 06-07-2017 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CAK77_RS15460 8130c4f506cc7d7ec01e6037cbd0abda 755 Pfam PF00013 KH domain 596 653 9.0E-11 T 06-07-2017 IPR004088 K Homology domain, type 1 GO:0003723 CAK77_RS15460 8130c4f506cc7d7ec01e6037cbd0abda 755 Pfam PF00575 S1 RNA binding domain 661 730 7.6E-14 T 06-07-2017 IPR003029 S1 domain GO:0003676 CAK77_RS15460 8130c4f506cc7d7ec01e6037cbd0abda 755 Gene3D G3DSA:3.30.230.70 11 256 4.6E-84 T 06-07-2017 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CAK77_RS15460 8130c4f506cc7d7ec01e6037cbd0abda 755 Gene3D G3DSA:3.30.230.70 344 583 5.0E-81 T 06-07-2017 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CAK77_RS15460 8130c4f506cc7d7ec01e6037cbd0abda 755 Gene3D G3DSA:1.10.10.400 271 343 6.5E-25 T 06-07-2017 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CAK77_RS15460 8130c4f506cc7d7ec01e6037cbd0abda 755 Pfam PF03725 3' exoribonuclease family, domain 2 159 213 5.6E-5 T 06-07-2017 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CAK77_RS15460 8130c4f506cc7d7ec01e6037cbd0abda 755 Pfam PF01138 3' exoribonuclease family, domain 1 356 488 6.1E-18 T 06-07-2017 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CAK77_RS15460 8130c4f506cc7d7ec01e6037cbd0abda 755 Pfam PF01138 3' exoribonuclease family, domain 1 25 156 1.3E-17 T 06-07-2017 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CAK77_RS15460 8130c4f506cc7d7ec01e6037cbd0abda 755 SUPERFAMILY SSF50249 660 730 2.07E-15 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS03230 1abc048f429b703eca3671183e07884c 261 SUPERFAMILY SSF56529 3 260 6.54E-73 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAK77_RS03230 1abc048f429b703eca3671183e07884c 261 Gene3D G3DSA:3.90.850.10 2 260 1.4E-82 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAK77_RS03230 1abc048f429b703eca3671183e07884c 261 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 104 257 8.5E-11 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAK77_RS14305 fcaee517281fba4f9d2b8c47b3959479 123 SUPERFAMILY SSF49764 6 115 2.55E-23 T 06-07-2017 IPR008978 HSP20-like chaperone CAK77_RS14305 fcaee517281fba4f9d2b8c47b3959479 123 Gene3D G3DSA:2.60.40.790 26 118 7.8E-22 T 06-07-2017 IPR008978 HSP20-like chaperone CAK77_RS14305 fcaee517281fba4f9d2b8c47b3959479 123 Pfam PF00011 Hsp20/alpha crystallin family 26 119 2.2E-18 T 06-07-2017 IPR002068 Alpha crystallin/Hsp20 domain CAK77_RS03555 f562f8d2bf6692afccd937ff474de23c 235 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 45 2.0E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS03555 f562f8d2bf6692afccd937ff474de23c 235 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 53 76 2.0E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS03555 f562f8d2bf6692afccd937ff474de23c 235 Pfam PF00440 Bacterial regulatory proteins, tetR family 32 77 4.6E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS03555 f562f8d2bf6692afccd937ff474de23c 235 SUPERFAMILY SSF46689 23 93 8.21E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS03555 f562f8d2bf6692afccd937ff474de23c 235 Gene3D G3DSA:1.10.357.10 26 212 5.2E-25 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS04975 89b077e9ed154a17fab4024b8007990b 672 Gene3D G3DSA:3.30.565.10 21 131 4.6E-14 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS04975 89b077e9ed154a17fab4024b8007990b 672 SUPERFAMILY SSF55874 5 200 1.31E-14 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS04975 89b077e9ed154a17fab4024b8007990b 672 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 25 125 4.7E-14 T 06-07-2017 CAK77_RS12170 3431143efb1585d306c47dde5528c34e 482 Pfam PF01266 FAD dependent oxidoreductase 28 372 1.0E-39 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CAK77_RS12170 3431143efb1585d306c47dde5528c34e 482 SUPERFAMILY SSF51971 24 261 3.65E-35 T 06-07-2017 CAK77_RS12170 3431143efb1585d306c47dde5528c34e 482 SUPERFAMILY SSF51971 322 384 3.65E-35 T 06-07-2017 CAK77_RS12170 3431143efb1585d306c47dde5528c34e 482 Gene3D G3DSA:2.102.10.10 370 478 1.4E-20 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK77_RS12170 3431143efb1585d306c47dde5528c34e 482 SUPERFAMILY SSF50022 431 478 1.7E-15 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK77_RS12170 3431143efb1585d306c47dde5528c34e 482 Pfam PF00355 Rieske [2Fe-2S] domain 432 476 4.1E-6 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK77_RS12170 3431143efb1585d306c47dde5528c34e 482 Gene3D G3DSA:3.50.50.60 20 120 4.7E-29 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS12170 3431143efb1585d306c47dde5528c34e 482 Gene3D G3DSA:3.50.50.60 159 369 4.7E-29 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS13240 4beb52a5f9ca0f8927893b9577718132 459 Hamap MF_01113 DNA polymerase IV [dinB]. 5 353 33.022 T 06-07-2017 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 CAK77_RS13240 4beb52a5f9ca0f8927893b9577718132 459 Gene3D G3DSA:3.30.1490.100 247 352 4.0E-25 T 06-07-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CAK77_RS13240 4beb52a5f9ca0f8927893b9577718132 459 Pfam PF11798 IMS family HHH motif 171 202 1.1E-8 T 06-07-2017 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 CAK77_RS13240 4beb52a5f9ca0f8927893b9577718132 459 Gene3D G3DSA:3.30.70.270 73 168 3.1E-18 T 06-07-2017 CAK77_RS13240 4beb52a5f9ca0f8927893b9577718132 459 Gene3D G3DSA:1.10.150.20 170 243 2.3E-22 T 06-07-2017 CAK77_RS13240 4beb52a5f9ca0f8927893b9577718132 459 SUPERFAMILY SSF56672 6 243 3.56E-67 T 06-07-2017 CAK77_RS13240 4beb52a5f9ca0f8927893b9577718132 459 SUPERFAMILY SSF100879 245 344 9.42E-23 T 06-07-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CAK77_RS13240 4beb52a5f9ca0f8927893b9577718132 459 Pfam PF00817 impB/mucB/samB family 11 158 8.6E-35 T 06-07-2017 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CAK77_RS13240 4beb52a5f9ca0f8927893b9577718132 459 Pfam PF11799 impB/mucB/samB family C-terminal domain 241 350 1.4E-17 T 06-07-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CAK77_RS19455 9a435ae91ca3c71f10e02e562b24b782 156 Pfam PF13452 N-terminal half of MaoC dehydratase 8 137 1.4E-25 T 06-07-2017 CAK77_RS19455 9a435ae91ca3c71f10e02e562b24b782 156 Gene3D G3DSA:3.10.129.10 1 148 2.0E-21 T 06-07-2017 IPR029069 HotDog domain CAK77_RS19455 9a435ae91ca3c71f10e02e562b24b782 156 PIRSF PIRSF018072 1 150 4.7E-47 T 06-07-2017 IPR016709 Uncharacterised protein family UPF0336 CAK77_RS19455 9a435ae91ca3c71f10e02e562b24b782 156 SUPERFAMILY SSF54637 8 148 7.79E-29 T 06-07-2017 IPR029069 HotDog domain CAK77_RS19455 9a435ae91ca3c71f10e02e562b24b782 156 Hamap MF_00799 UPF0336 protein . 1 148 29.81 T 06-07-2017 IPR016709 Uncharacterised protein family UPF0336 CAK77_RS13310 94cb75a0a759bd8ccd8c3e2830eb49a7 434 Gene3D G3DSA:3.10.580.10 288 407 5.5E-19 T 06-07-2017 CAK77_RS13310 94cb75a0a759bd8ccd8c3e2830eb49a7 434 Pfam PF03448 MgtE intracellular N domain 183 285 1.5E-18 T 06-07-2017 IPR006668 Magnesium transporter, MgtE intracellular domain CAK77_RS13310 94cb75a0a759bd8ccd8c3e2830eb49a7 434 SMART SM00116 360 408 1.5E-6 T 06-07-2017 IPR000644 CBS domain CAK77_RS13310 94cb75a0a759bd8ccd8c3e2830eb49a7 434 Pfam PF00571 CBS domain 353 407 6.5E-11 T 06-07-2017 IPR000644 CBS domain CAK77_RS13310 94cb75a0a759bd8ccd8c3e2830eb49a7 434 SUPERFAMILY SSF54631 288 411 1.64E-23 T 06-07-2017 CAK77_RS13310 94cb75a0a759bd8ccd8c3e2830eb49a7 434 Gene3D G3DSA:1.25.60.10 179 282 7.7E-20 T 06-07-2017 CAK77_RS13310 94cb75a0a759bd8ccd8c3e2830eb49a7 434 SMART SM00924 183 288 9.0E-23 T 06-07-2017 IPR006668 Magnesium transporter, MgtE intracellular domain CAK77_RS13310 94cb75a0a759bd8ccd8c3e2830eb49a7 434 SUPERFAMILY SSF158791 176 284 1.44E-18 T 06-07-2017 CAK77_RS13310 94cb75a0a759bd8ccd8c3e2830eb49a7 434 SUPERFAMILY SSF50346 12 78 3.14E-5 T 06-07-2017 IPR011033 PRC-barrel-like CAK77_RS21135 8e8040c3a6f81a7a14d231e6aacd8d9d 65 SUPERFAMILY SSF54285 1 65 2.62E-15 T 06-07-2017 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp CAK77_RS21135 8e8040c3a6f81a7a14d231e6aacd8d9d 65 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 3 65 2.5E-18 T 06-07-2017 IPR010035 ThiS, thiamine-biosynthesis CAK77_RS21135 8e8040c3a6f81a7a14d231e6aacd8d9d 65 Gene3D G3DSA:3.10.20.30 1 65 2.7E-24 T 06-07-2017 IPR012675 Beta-grasp domain CAK77_RS21135 8e8040c3a6f81a7a14d231e6aacd8d9d 65 Pfam PF02597 ThiS family 3 65 3.4E-13 T 06-07-2017 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 CAK77_RS17420 1fb450775ceede17c5aa6713d8f109cb 367 Hamap MF_00094 Peptide chain release factor 2 [prfB]. 1 363 38.564 T 06-07-2017 IPR020853 Peptide chain release factor 2, bacterial GO:0005737|GO:0006415|GO:0016149 CAK77_RS17420 1fb450775ceede17c5aa6713d8f109cb 367 SUPERFAMILY SSF75620 28 364 1.96E-121 T 06-07-2017 CAK77_RS17420 1fb450775ceede17c5aa6713d8f109cb 367 TIGRFAM TIGR00020 prfB: peptide chain release factor 2 4 363 3.4E-164 T 06-07-2017 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 CAK77_RS17420 1fb450775ceede17c5aa6713d8f109cb 367 Gene3D G3DSA:1.20.58.410 4 114 1.8E-32 T 06-07-2017 CAK77_RS17420 1fb450775ceede17c5aa6713d8f109cb 367 Gene3D G3DSA:3.30.160.20 227 304 6.2E-34 T 06-07-2017 IPR014720 Double-stranded RNA-binding domain CAK77_RS17420 1fb450775ceede17c5aa6713d8f109cb 367 Pfam PF00472 RF-1 domain 228 335 9.7E-37 T 06-07-2017 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CAK77_RS17420 1fb450775ceede17c5aa6713d8f109cb 367 SMART SM00937 83 193 8.2E-47 T 06-07-2017 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 CAK77_RS17420 1fb450775ceede17c5aa6713d8f109cb 367 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 243 259 - T 06-07-2017 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CAK77_RS17420 1fb450775ceede17c5aa6713d8f109cb 367 Pfam PF03462 PCRF domain 29 218 2.9E-55 T 06-07-2017 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 CAK77_RS18140 923f6abcb889ae478be035e743701a8e 599 SUPERFAMILY SSF56059 90 334 4.95E-59 T 06-07-2017 CAK77_RS18140 923f6abcb889ae478be035e743701a8e 599 Gene3D G3DSA:3.30.470.20 210 456 1.6E-91 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAK77_RS18140 923f6abcb889ae478be035e743701a8e 599 SUPERFAMILY SSF51230 529 598 8.11E-20 T 06-07-2017 IPR011053 Single hybrid motif CAK77_RS18140 923f6abcb889ae478be035e743701a8e 599 SMART SM00878 342 452 3.5E-56 T 06-07-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAK77_RS18140 923f6abcb889ae478be035e743701a8e 599 Pfam PF00289 Biotin carboxylase, N-terminal domain 9 117 2.1E-42 T 06-07-2017 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAK77_RS18140 923f6abcb889ae478be035e743701a8e 599 Pfam PF02785 Biotin carboxylase C-terminal domain 342 452 1.7E-35 T 06-07-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAK77_RS18140 923f6abcb889ae478be035e743701a8e 599 Gene3D G3DSA:3.30.1490.20 137 209 2.5E-25 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CAK77_RS18140 923f6abcb889ae478be035e743701a8e 599 SUPERFAMILY SSF51246 336 456 1.26E-36 T 06-07-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAK77_RS18140 923f6abcb889ae478be035e743701a8e 599 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 293 300 - T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CAK77_RS18140 923f6abcb889ae478be035e743701a8e 599 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 122 329 2.9E-80 T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CAK77_RS18140 923f6abcb889ae478be035e743701a8e 599 SUPERFAMILY SSF52440 7 120 7.05E-46 T 06-07-2017 IPR016185 Pre-ATP-grasp domain CAK77_RS18140 923f6abcb889ae478be035e743701a8e 599 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 555 572 - T 06-07-2017 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAK77_RS18140 923f6abcb889ae478be035e743701a8e 599 Gene3D G3DSA:2.40.50.100 529 599 3.4E-23 T 06-07-2017 CAK77_RS18140 923f6abcb889ae478be035e743701a8e 599 Gene3D G3DSA:3.40.50.20 9 136 1.1E-46 T 06-07-2017 IPR016185 Pre-ATP-grasp domain CAK77_RS18140 923f6abcb889ae478be035e743701a8e 599 Pfam PF00364 Biotin-requiring enzyme 533 598 4.7E-18 T 06-07-2017 IPR000089 Biotin/lipoyl attachment CAK77_RS12825 483cdaf0a7ec7c8a92202a481965fb99 304 Gene3D G3DSA:3.40.50.1820 2 139 3.1E-48 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS12825 483cdaf0a7ec7c8a92202a481965fb99 304 Gene3D G3DSA:3.40.50.1820 221 291 3.1E-48 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS12825 483cdaf0a7ec7c8a92202a481965fb99 304 SUPERFAMILY SSF53474 3 144 1.02E-41 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS12825 483cdaf0a7ec7c8a92202a481965fb99 304 SUPERFAMILY SSF53474 190 292 1.02E-41 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS12825 483cdaf0a7ec7c8a92202a481965fb99 304 Pfam PF12146 Serine aminopeptidase, S33 30 257 5.3E-12 T 06-07-2017 IPR022742 Serine aminopeptidase, S33 CAK77_RS01665 d98c159a632a36039b4e7ec16170aa1b 327 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 14 175 1.8E-24 T 06-07-2017 IPR006054 DNA polymerase III, epsilon subunit GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAK77_RS01665 d98c159a632a36039b4e7ec16170aa1b 327 SUPERFAMILY SSF53098 13 264 8.18E-47 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAK77_RS01665 d98c159a632a36039b4e7ec16170aa1b 327 Pfam PF00929 Exonuclease 15 169 4.9E-24 T 06-07-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III CAK77_RS01665 d98c159a632a36039b4e7ec16170aa1b 327 SMART SM00479 13 178 1.5E-43 T 06-07-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III CAK77_RS01665 d98c159a632a36039b4e7ec16170aa1b 327 Gene3D G3DSA:3.30.420.10 11 181 1.1E-46 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAK77_RS01665 d98c159a632a36039b4e7ec16170aa1b 327 Gene3D G3DSA:3.40.50.10190 228 300 6.7E-6 T 06-07-2017 IPR001357 BRCT domain CAK77_RS01630 f0978914ecc5c43801f6c0781b2d4119 202 Hamap MF_00017 Recombination protein RecR [recR]. 1 202 100.954 T 06-07-2017 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 CAK77_RS01630 f0978914ecc5c43801f6c0781b2d4119 202 SMART SM00493 79 168 1.1E-12 T 06-07-2017 IPR006171 Toprim domain CAK77_RS01630 f0978914ecc5c43801f6c0781b2d4119 202 SUPERFAMILY SSF111304 3 202 8.5E-68 T 06-07-2017 IPR023627 Recombination protein RecR CAK77_RS01630 f0978914ecc5c43801f6c0781b2d4119 202 ProSitePatterns PS01300 RecR protein signature. 56 77 - T 06-07-2017 IPR015967 Recombination protein RecR, conserved site GO:0006281|GO:0006310 CAK77_RS01630 f0978914ecc5c43801f6c0781b2d4119 202 Gene3D G3DSA:3.40.50.140 138 173 1.2E-4 T 06-07-2017 IPR006171 Toprim domain CAK77_RS01630 f0978914ecc5c43801f6c0781b2d4119 202 Pfam PF02132 RecR protein 39 77 3.9E-15 T 06-07-2017 IPR023628 Recombination protein RecR, C4-type zinc finger CAK77_RS01630 f0978914ecc5c43801f6c0781b2d4119 202 Pfam PF13662 Toprim domain 81 175 4.8E-22 T 06-07-2017 IPR006171 Toprim domain CAK77_RS01630 f0978914ecc5c43801f6c0781b2d4119 202 TIGRFAM TIGR00615 recR: recombination protein RecR 2 200 3.5E-79 T 06-07-2017 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 CAK77_RS17705 8c8019497d6671f695cf8baa7f26f66f 368 Gene3D G3DSA:3.60.120.10 81 363 2.9E-83 T 06-07-2017 IPR005801 ADC synthase GO:0009058 CAK77_RS17705 8c8019497d6671f695cf8baa7f26f66f 368 Pfam PF00425 chorismate binding enzyme 94 355 1.7E-69 T 06-07-2017 IPR015890 Chorismate-utilising enzyme, C-terminal CAK77_RS17705 8c8019497d6671f695cf8baa7f26f66f 368 TIGRFAM TIGR00543 isochor_syn: isochorismate synthase 83 361 3.2E-76 T 06-07-2017 IPR004561 Isochorismate synthase GO:0008909|GO:0009058 KEGG: 00130+5.4.4.2|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6406 CAK77_RS17705 8c8019497d6671f695cf8baa7f26f66f 368 SUPERFAMILY SSF56322 26 364 1.23E-82 T 06-07-2017 IPR005801 ADC synthase GO:0009058 CAK77_RS17705 8c8019497d6671f695cf8baa7f26f66f 368 PRINTS PR00095 Anthranilate synthase component I signature 203 216 1.2E-5 T 06-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CAK77_RS17705 8c8019497d6671f695cf8baa7f26f66f 368 PRINTS PR00095 Anthranilate synthase component I signature 295 309 1.2E-5 T 06-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CAK77_RS17705 8c8019497d6671f695cf8baa7f26f66f 368 PRINTS PR00095 Anthranilate synthase component I signature 310 324 1.2E-5 T 06-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CAK77_RS17705 8c8019497d6671f695cf8baa7f26f66f 368 PRINTS PR00095 Anthranilate synthase component I signature 217 230 1.2E-5 T 06-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CAK77_RS15235 2b50225fca47e69b792e87ca99460e40 346 SMART SM00382 59 230 5.9E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS15235 2b50225fca47e69b792e87ca99460e40 346 Gene3D G3DSA:3.30.250.10 270 328 5.3E-28 T 06-07-2017 IPR023400 DNA recombination and repair protein RecA, C-terminal CAK77_RS15235 2b50225fca47e69b792e87ca99460e40 346 PRINTS PR00142 RecA protein signature 212 240 1.0E-83 T 06-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CAK77_RS15235 2b50225fca47e69b792e87ca99460e40 346 PRINTS PR00142 RecA protein signature 95 124 1.0E-83 T 06-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CAK77_RS15235 2b50225fca47e69b792e87ca99460e40 346 PRINTS PR00142 RecA protein signature 299 316 1.0E-83 T 06-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CAK77_RS15235 2b50225fca47e69b792e87ca99460e40 346 PRINTS PR00142 RecA protein signature 167 196 1.0E-83 T 06-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CAK77_RS15235 2b50225fca47e69b792e87ca99460e40 346 PRINTS PR00142 RecA protein signature 245 274 1.0E-83 T 06-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CAK77_RS15235 2b50225fca47e69b792e87ca99460e40 346 PRINTS PR00142 RecA protein signature 129 158 1.0E-83 T 06-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CAK77_RS15235 2b50225fca47e69b792e87ca99460e40 346 Hamap MF_00268 Protein RecA [recA]. 7 331 53.131 T 06-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CAK77_RS15235 2b50225fca47e69b792e87ca99460e40 346 Pfam PF00154 recA bacterial DNA recombination protein 9 270 2.2E-145 T 06-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CAK77_RS15235 2b50225fca47e69b792e87ca99460e40 346 SUPERFAMILY SSF52540 6 269 3.89E-70 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS15235 2b50225fca47e69b792e87ca99460e40 346 ProSitePatterns PS00321 recA signature. 215 223 - T 06-07-2017 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 CAK77_RS15235 2b50225fca47e69b792e87ca99460e40 346 SUPERFAMILY SSF54752 270 328 3.79E-20 T 06-07-2017 IPR023400 DNA recombination and repair protein RecA, C-terminal CAK77_RS15235 2b50225fca47e69b792e87ca99460e40 346 Gene3D G3DSA:3.40.50.300 28 269 6.5E-88 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS15235 2b50225fca47e69b792e87ca99460e40 346 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 6 326 3.9E-175 T 06-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CAK77_RS04165 651c47d33d61a32eea1dffb232fdec59 494 Pfam PF00823 PPE family 9 165 9.1E-58 T 06-07-2017 IPR000030 PPE family CAK77_RS04165 651c47d33d61a32eea1dffb232fdec59 494 SUPERFAMILY SSF140459 6 178 1.73E-59 T 06-07-2017 CAK77_RS04710 2dea892be3acc6ff7c69fd99c221a274 362 SUPERFAMILY SSF51905 175 213 7.77E-8 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS04710 2dea892be3acc6ff7c69fd99c221a274 362 SUPERFAMILY SSF51905 245 358 7.77E-8 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS04710 2dea892be3acc6ff7c69fd99c221a274 362 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 175 193 5.1E-6 T 06-07-2017 CAK77_RS04710 2dea892be3acc6ff7c69fd99c221a274 362 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 5.1E-6 T 06-07-2017 CAK77_RS04710 2dea892be3acc6ff7c69fd99c221a274 362 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 88 209 1.2E-16 T 06-07-2017 CAK77_RS04710 2dea892be3acc6ff7c69fd99c221a274 362 Gene3D G3DSA:3.50.50.60 2 155 1.1E-17 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS04710 2dea892be3acc6ff7c69fd99c221a274 362 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 3 25 7.8E-10 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAK77_RS04710 2dea892be3acc6ff7c69fd99c221a274 362 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 171 195 7.8E-10 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAK77_RS04710 2dea892be3acc6ff7c69fd99c221a274 362 Gene3D G3DSA:3.50.50.60 258 290 1.6E-25 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS04710 2dea892be3acc6ff7c69fd99c221a274 362 Gene3D G3DSA:3.50.50.60 156 213 1.6E-25 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS04710 2dea892be3acc6ff7c69fd99c221a274 362 SUPERFAMILY SSF51905 3 186 1.55E-32 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS04710 2dea892be3acc6ff7c69fd99c221a274 362 SUPERFAMILY SSF51905 254 293 1.55E-32 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS10575 39bf73cabfa371bc2ca340eec1a9e9d7 292 Gene3D G3DSA:3.60.20.10 55 268 5.7E-48 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAK77_RS10575 39bf73cabfa371bc2ca340eec1a9e9d7 292 SUPERFAMILY SSF56235 27 270 4.27E-48 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAK77_RS10575 39bf73cabfa371bc2ca340eec1a9e9d7 292 TIGRFAM TIGR03690 20S_bact_beta: proteasome, beta subunit 51 276 3.3E-105 T 06-07-2017 IPR022483 Peptidase T1A, proteasome beta-subunit, actinobacteria GO:0004298|GO:0005839|GO:0010498 CAK77_RS10575 39bf73cabfa371bc2ca340eec1a9e9d7 292 Hamap MF_02113_B Proteasome subunit beta [prcB]. 9 281 45.849 T 06-07-2017 IPR022483 Peptidase T1A, proteasome beta-subunit, actinobacteria GO:0004298|GO:0005839|GO:0010498 CAK77_RS10575 39bf73cabfa371bc2ca340eec1a9e9d7 292 Pfam PF00227 Proteasome subunit 53 237 1.4E-25 T 06-07-2017 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5687128|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-983168 CAK77_RS07680 ef6ca5168f4e9615641fa2b7848f3e12 208 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 67 7.6E-18 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS07680 ef6ca5168f4e9615641fa2b7848f3e12 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 35 1.3E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS07680 ef6ca5168f4e9615641fa2b7848f3e12 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 66 1.3E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS07680 ef6ca5168f4e9615641fa2b7848f3e12 208 Gene3D G3DSA:1.10.357.10 69 208 9.6E-23 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS07680 ef6ca5168f4e9615641fa2b7848f3e12 208 Gene3D G3DSA:1.10.10.60 10 68 2.7E-22 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS07680 ef6ca5168f4e9615641fa2b7848f3e12 208 SUPERFAMILY SSF46689 10 80 2.15E-20 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS07680 ef6ca5168f4e9615641fa2b7848f3e12 208 SUPERFAMILY SSF48498 106 207 4.17E-14 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS02665 8edc4e962e893b524895c81ba47ff205 1342 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 78 455 1.3E-96 T 06-07-2017 IPR010071 Amino acid adenylation domain CAK77_RS02665 8edc4e962e893b524895c81ba47ff205 1342 Gene3D G3DSA:2.160.10.10 981 1081 2.8E-9 T 06-07-2017 CAK77_RS02665 8edc4e962e893b524895c81ba47ff205 1342 Gene3D G3DSA:3.40.50.980 51 205 1.1E-32 T 06-07-2017 CAK77_RS02665 8edc4e962e893b524895c81ba47ff205 1342 Pfam PF00501 AMP-binding enzyme 59 433 9.8E-66 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK77_RS02665 8edc4e962e893b524895c81ba47ff205 1342 SUPERFAMILY SSF51161 1200 1322 1.25E-18 T 06-07-2017 IPR011004 Trimeric LpxA-like CAK77_RS02665 8edc4e962e893b524895c81ba47ff205 1342 ProSitePatterns PS00455 Putative AMP-binding domain signature. 182 193 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK77_RS02665 8edc4e962e893b524895c81ba47ff205 1342 SUPERFAMILY SSF51161 904 1080 6.93E-17 T 06-07-2017 IPR011004 Trimeric LpxA-like CAK77_RS02665 8edc4e962e893b524895c81ba47ff205 1342 SMART SM00823 Phosphopantetheine attachment site 541 609 0.004 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAK77_RS02665 8edc4e962e893b524895c81ba47ff205 1342 SUPERFAMILY SSF47336 539 606 3.01E-11 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS02665 8edc4e962e893b524895c81ba47ff205 1342 Gene3D G3DSA:1.10.1200.10 538 608 6.7E-15 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS02665 8edc4e962e893b524895c81ba47ff205 1342 Gene3D G3DSA:2.160.10.10 700 844 2.6E-16 T 06-07-2017 CAK77_RS02665 8edc4e962e893b524895c81ba47ff205 1342 Gene3D G3DSA:2.160.10.10 1214 1322 2.5E-20 T 06-07-2017 CAK77_RS02665 8edc4e962e893b524895c81ba47ff205 1342 SUPERFAMILY SSF51161 734 855 4.3E-18 T 06-07-2017 IPR011004 Trimeric LpxA-like CAK77_RS02665 8edc4e962e893b524895c81ba47ff205 1342 Pfam PF00550 Phosphopantetheine attachment site 543 605 1.5E-10 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS02665 8edc4e962e893b524895c81ba47ff205 1342 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 793 822 0.0021 T 06-07-2017 IPR001451 Hexapeptide repeat CAK77_RS02665 8edc4e962e893b524895c81ba47ff205 1342 SUPERFAMILY SSF56801 47 522 1.31E-108 T 06-07-2017 CAK77_RS02665 8edc4e962e893b524895c81ba47ff205 1342 Gene3D G3DSA:2.30.38.10 350 422 5.1E-15 T 06-07-2017 CAK77_RS02665 8edc4e962e893b524895c81ba47ff205 1342 TIGRFAM TIGR02353 NRPS_term_dom: non-ribosomal peptide synthetase terminal domain of unknown function 629 1314 1.2E-221 T 06-07-2017 IPR012728 Non-ribosomal peptide synthetase, C-terminal CAK77_RS02665 8edc4e962e893b524895c81ba47ff205 1342 Gene3D G3DSA:3.30.300.30 428 524 1.3E-22 T 06-07-2017 CAK77_RS02665 8edc4e962e893b524895c81ba47ff205 1342 Gene3D G3DSA:3.40.50.980 215 349 2.3E-34 T 06-07-2017 CAK77_RS02665 8edc4e962e893b524895c81ba47ff205 1342 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 801 829 - T 06-07-2017 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CAK77_RS08225 5af64a9014e2f8701f1c456948e43da6 482 SUPERFAMILY SSF102741 366 438 2.48E-20 T 06-07-2017 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 CAK77_RS08225 5af64a9014e2f8701f1c456948e43da6 482 SUPERFAMILY SSF82051 4 157 2.49E-46 T 06-07-2017 IPR006169 GTP1/OBG domain GO:0005525 CAK77_RS08225 5af64a9014e2f8701f1c456948e43da6 482 Gene3D G3DSA:2.70.210.12 3 156 2.0E-48 T 06-07-2017 IPR006169 GTP1/OBG domain GO:0005525 CAK77_RS08225 5af64a9014e2f8701f1c456948e43da6 482 Pfam PF01926 50S ribosome-binding GTPase 161 293 2.9E-22 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 CAK77_RS08225 5af64a9014e2f8701f1c456948e43da6 482 Pfam PF09269 Domain of unknown function (DUF1967) 366 436 2.2E-24 T 06-07-2017 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 CAK77_RS08225 5af64a9014e2f8701f1c456948e43da6 482 Pfam PF01018 GTP1/OBG 4 157 1.5E-51 T 06-07-2017 IPR006169 GTP1/OBG domain GO:0005525 CAK77_RS08225 5af64a9014e2f8701f1c456948e43da6 482 ProSitePatterns PS00905 GTP1/OBG family signature. 212 225 - T 06-07-2017 IPR006074 GTP1/OBG, conserved site GO:0005525 CAK77_RS08225 5af64a9014e2f8701f1c456948e43da6 482 SUPERFAMILY SSF52540 161 359 5.02E-49 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS08225 5af64a9014e2f8701f1c456948e43da6 482 Hamap MF_01454 GTPase Obg [obg]. 3 340 43.921 T 06-07-2017 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 CAK77_RS08225 5af64a9014e2f8701f1c456948e43da6 482 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 162 182 3.0E-35 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 CAK77_RS08225 5af64a9014e2f8701f1c456948e43da6 482 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 210 225 3.0E-35 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 CAK77_RS08225 5af64a9014e2f8701f1c456948e43da6 482 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 227 245 3.0E-35 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 CAK77_RS08225 5af64a9014e2f8701f1c456948e43da6 482 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 183 201 3.0E-35 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 CAK77_RS08225 5af64a9014e2f8701f1c456948e43da6 482 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 4 339 1.4E-124 T 06-07-2017 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 CAK77_RS08225 5af64a9014e2f8701f1c456948e43da6 482 Gene3D G3DSA:3.40.50.300 160 344 1.3E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS08225 5af64a9014e2f8701f1c456948e43da6 482 TIGRFAM TIGR03595 Obg_CgtA_exten: Obg family GTPase CgtA, C-terminal extension 371 437 1.4E-23 T 06-07-2017 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 CAK77_RS15475 b2ed80e2a6f0c568312760e14fca5f2f 320 Gene3D G3DSA:3.40.50.620 3 180 2.8E-64 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS15475 b2ed80e2a6f0c568312760e14fca5f2f 320 SUPERFAMILY SSF52374 16 175 1.28E-31 T 06-07-2017 CAK77_RS15475 b2ed80e2a6f0c568312760e14fca5f2f 320 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 18 317 1.6E-73 T 06-07-2017 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CAK77_RS15475 b2ed80e2a6f0c568312760e14fca5f2f 320 Pfam PF01687 Riboflavin kinase 184 317 3.2E-34 T 06-07-2017 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 CAK77_RS15475 b2ed80e2a6f0c568312760e14fca5f2f 320 Pfam PF06574 FAD synthetase 12 166 3.3E-54 T 06-07-2017 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CAK77_RS15475 b2ed80e2a6f0c568312760e14fca5f2f 320 SUPERFAMILY SSF82114 174 318 5.67E-40 T 06-07-2017 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 CAK77_RS15475 b2ed80e2a6f0c568312760e14fca5f2f 320 PIRSF PIRSF004491 2 320 1.1E-100 T 06-07-2017 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CAK77_RS15475 b2ed80e2a6f0c568312760e14fca5f2f 320 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 18 83 1.4E-7 T 06-07-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CAK77_RS15475 b2ed80e2a6f0c568312760e14fca5f2f 320 Gene3D G3DSA:2.40.30.30 181 319 5.1E-44 T 06-07-2017 IPR023465 Riboflavin kinase domain GO:0008531|GO:0009231 Reactome: R-HSA-196843 CAK77_RS15475 b2ed80e2a6f0c568312760e14fca5f2f 320 SMART SM00904 183 318 7.7E-53 T 06-07-2017 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 CAK77_RS04615 62054cd800f27b688aed41d206903815 3699 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1733 1749 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site CAK77_RS04615 62054cd800f27b688aed41d206903815 3699 SMART SM01294 1478 1544 1.1E-6 T 06-07-2017 CAK77_RS04615 62054cd800f27b688aed41d206903815 3699 SUPERFAMILY SSF47336 1472 1585 2.75E-23 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS04615 62054cd800f27b688aed41d206903815 3699 SUPERFAMILY SSF51735 3096 3248 8.34E-34 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS04615 62054cd800f27b688aed41d206903815 3699 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1503 1518 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site CAK77_RS04615 62054cd800f27b688aed41d206903815 3699 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 175 191 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site CAK77_RS04615 62054cd800f27b688aed41d206903815 3699 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1571 1820 6.2E-95 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAK77_RS04615 62054cd800f27b688aed41d206903815 3699 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 15 262 1.4E-91 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAK77_RS04615 62054cd800f27b688aed41d206903815 3699 Gene3D G3DSA:3.40.366.10 2298 2420 8.6E-76 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAK77_RS04615 62054cd800f27b688aed41d206903815 3699 Gene3D G3DSA:3.40.366.10 2093 2232 8.6E-76 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAK77_RS04615 62054cd800f27b688aed41d206903815 3699 Gene3D G3DSA:3.40.50.720 1191 1403 1.9E-44 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS04615 62054cd800f27b688aed41d206903815 3699 Gene3D G3DSA:3.40.50.720 3313 3525 3.0E-35 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS04615 62054cd800f27b688aed41d206903815 3699 SMART SM00829 2997 3302 1.4E-149 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAK77_RS04615 62054cd800f27b688aed41d206903815 3699 Gene3D G3DSA:3.30.70.250 674 729 3.2E-5 T 06-07-2017 CAK77_RS04615 62054cd800f27b688aed41d206903815 3699 Gene3D G3DSA:3.30.70.250 2236 2295 6.0E-5 T 06-07-2017 CAK77_RS04615 62054cd800f27b688aed41d206903815 3699 SMART SM00826 2470 2638 1.5E-36 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAK77_RS04615 62054cd800f27b688aed41d206903815 3699 SUPERFAMILY SSF55048 674 735 1.27E-6 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CAK77_RS04615 62054cd800f27b688aed41d206903815 3699 Gene3D G3DSA:3.40.366.10 538 669 2.9E-74 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAK77_RS04615 62054cd800f27b688aed41d206903815 3699 Gene3D G3DSA:3.40.366.10 735 849 2.9E-74 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAK77_RS04615 62054cd800f27b688aed41d206903815 3699 SUPERFAMILY SSF51735 962 1177 3.49E-36 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS04615 62054cd800f27b688aed41d206903815 3699 SUPERFAMILY SSF51735 1189 1426 2.22E-47 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS04615 62054cd800f27b688aed41d206903815 3699 SUPERFAMILY SSF52151 543 675 9.68E-67 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAK77_RS04615 62054cd800f27b688aed41d206903815 3699 SUPERFAMILY SSF52151 737 832 9.68E-67 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAK77_RS04615 62054cd800f27b688aed41d206903815 3699 Gene3D G3DSA:3.40.47.10 1577 1832 7.9E-99 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS04615 62054cd800f27b688aed41d206903815 3699 Pfam PF14765 Polyketide synthase dehydratase 2484 2763 3.9E-46 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAK77_RS04615 62054cd800f27b688aed41d206903815 3699 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 3015 3072 6.6E-5 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAK77_RS04615 62054cd800f27b688aed41d206903815 3699 SUPERFAMILY SSF53901 1566 1941 1.45E-100 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS04615 62054cd800f27b688aed41d206903815 3699 SUPERFAMILY SSF51735 3310 3566 2.29E-42 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS04615 62054cd800f27b688aed41d206903815 3699 Gene3D G3DSA:3.40.47.10 14 274 1.0E-98 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS04615 62054cd800f27b688aed41d206903815 3699 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1948 2068 2.6E-21 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAK77_RS04615 62054cd800f27b688aed41d206903815 3699 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 390 509 1.7E-19 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAK77_RS04615 62054cd800f27b688aed41d206903815 3699 Pfam PF00698 Acyl transferase domain 2105 2426 1.1E-53 T 06-07-2017 IPR014043 Acyl transferase CAK77_RS04615 62054cd800f27b688aed41d206903815 3699 Pfam PF00698 Acyl transferase domain 546 856 8.0E-53 T 06-07-2017 IPR014043 Acyl transferase CAK77_RS04615 62054cd800f27b688aed41d206903815 3699 SUPERFAMILY SSF50129 2992 3131 1.73E-30 T 06-07-2017 IPR011032 GroES-like CAK77_RS04615 62054cd800f27b688aed41d206903815 3699 Pfam PF13602 Zinc-binding dehydrogenase 3164 3301 2.8E-21 T 06-07-2017 CAK77_RS04615 62054cd800f27b688aed41d206903815 3699 Gene3D G3DSA:3.40.47.10 1833 1999 1.2E-63 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS04615 62054cd800f27b688aed41d206903815 3699 Gene3D G3DSA:3.40.47.10 275 439 3.5E-62 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS04615 62054cd800f27b688aed41d206903815 3699 SUPERFAMILY SSF52151 2103 2237 3.14E-67 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAK77_RS04615 62054cd800f27b688aed41d206903815 3699 SUPERFAMILY SSF52151 2299 2392 3.14E-67 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAK77_RS04615 62054cd800f27b688aed41d206903815 3699 Pfam PF00550 Phosphopantetheine attachment site 1478 1544 5.4E-17 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS04615 62054cd800f27b688aed41d206903815 3699 Pfam PF00550 Phosphopantetheine attachment site 3593 3658 3.0E-10 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS04615 62054cd800f27b688aed41d206903815 3699 SMART SM00825 Beta-ketoacyl synthase 14 440 4.5E-217 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAK77_RS04615 62054cd800f27b688aed41d206903815 3699 SMART SM00825 Beta-ketoacyl synthase 1573 1998 7.4E-221 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAK77_RS04615 62054cd800f27b688aed41d206903815 3699 SUPERFAMILY SSF47336 3588 3680 1.83E-15 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS04615 62054cd800f27b688aed41d206903815 3699 SUPERFAMILY SSF55048 2236 2298 9.02E-8 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CAK77_RS04615 62054cd800f27b688aed41d206903815 3699 SUPERFAMILY SSF53901 11 131 1.97E-101 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS04615 62054cd800f27b688aed41d206903815 3699 SUPERFAMILY SSF53901 158 376 1.97E-101 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS04615 62054cd800f27b688aed41d206903815 3699 Gene3D G3DSA:1.10.1200.10 1475 1576 3.6E-20 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS04615 62054cd800f27b688aed41d206903815 3699 Gene3D G3DSA:1.10.1200.10 3590 3682 3.3E-15 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS04615 62054cd800f27b688aed41d206903815 3699 Gene3D G3DSA:3.90.180.10 2994 3127 1.3E-43 T 06-07-2017 IPR011032 GroES-like CAK77_RS04615 62054cd800f27b688aed41d206903815 3699 SMART SM00823 Phosphopantetheine attachment site 1477 1548 2.0E-22 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAK77_RS04615 62054cd800f27b688aed41d206903815 3699 SMART SM00823 Phosphopantetheine attachment site 3590 3662 2.6E-18 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAK77_RS04615 62054cd800f27b688aed41d206903815 3699 Pfam PF08659 KR domain 1192 1369 5.3E-59 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAK77_RS04615 62054cd800f27b688aed41d206903815 3699 Pfam PF08659 KR domain 3315 3492 1.1E-54 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAK77_RS04615 62054cd800f27b688aed41d206903815 3699 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1828 1945 1.0E-40 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAK77_RS04615 62054cd800f27b688aed41d206903815 3699 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 271 387 2.1E-40 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAK77_RS04615 62054cd800f27b688aed41d206903815 3699 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 547 846 4.3E-103 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain CAK77_RS04615 62054cd800f27b688aed41d206903815 3699 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2106 2408 3.7E-101 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain CAK77_RS04615 62054cd800f27b688aed41d206903815 3699 SUPERFAMILY SSF51735 2771 2976 4.33E-28 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS04615 62054cd800f27b688aed41d206903815 3699 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1192 1371 2.7E-43 T 06-07-2017 CAK77_RS04615 62054cd800f27b688aed41d206903815 3699 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3314 3494 7.5E-44 T 06-07-2017 CAK77_RS04615 62054cd800f27b688aed41d206903815 3699 Gene3D G3DSA:3.40.50.720 3128 3220 2.3E-26 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS03280 8bf2b94316638e5ecad581a2b16195b8 533 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 332 351 3.9E-14 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS03280 8bf2b94316638e5ecad581a2b16195b8 533 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 246 270 3.9E-14 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS03280 8bf2b94316638e5ecad581a2b16195b8 533 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 384 410 3.9E-14 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS03280 8bf2b94316638e5ecad581a2b16195b8 533 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 145 164 3.9E-14 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS03280 8bf2b94316638e5ecad581a2b16195b8 533 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 175 199 3.9E-14 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS03280 8bf2b94316638e5ecad581a2b16195b8 533 Pfam PF00361 Proton-conducting membrane transporter 139 427 7.6E-65 T 06-07-2017 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS20155 32c014c72bde237d5eb5fbb4553c2669 306 Gene3D G3DSA:3.40.50.720 9 244 1.5E-71 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS20155 32c014c72bde237d5eb5fbb4553c2669 306 Pfam PF00106 short chain dehydrogenase 10 194 4.4E-54 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS20155 32c014c72bde237d5eb5fbb4553c2669 306 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 6.8E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS20155 32c014c72bde237d5eb5fbb4553c2669 306 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 6.8E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS20155 32c014c72bde237d5eb5fbb4553c2669 306 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 6.8E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS20155 32c014c72bde237d5eb5fbb4553c2669 306 SUPERFAMILY SSF51735 5 277 1.54E-68 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS20155 32c014c72bde237d5eb5fbb4553c2669 306 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 8.7E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS20155 32c014c72bde237d5eb5fbb4553c2669 306 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 8.7E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS20155 32c014c72bde237d5eb5fbb4553c2669 306 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 8.7E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS20155 32c014c72bde237d5eb5fbb4553c2669 306 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 8.7E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS20155 32c014c72bde237d5eb5fbb4553c2669 306 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 8.7E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS20155 32c014c72bde237d5eb5fbb4553c2669 306 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK77_RS08590 52c142703313e82429a13a68f266b769 501 SUPERFAMILY SSF53383 63 490 6.35E-103 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK77_RS08590 52c142703313e82429a13a68f266b769 501 ProSitePatterns PS00392 DDC / GAD / HDC / TyrDC pyridoxal-phosphate attachment site. 306 327 - T 06-07-2017 IPR021115 Pyridoxal-phosphate binding site GO:0016831 CAK77_RS08590 52c142703313e82429a13a68f266b769 501 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 87 421 1.0E-47 T 06-07-2017 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 CAK77_RS08590 52c142703313e82429a13a68f266b769 501 Gene3D G3DSA:3.40.640.10 98 375 2.7E-89 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK77_RS08590 52c142703313e82429a13a68f266b769 501 Gene3D G3DSA:3.90.1150.10 376 489 8.1E-29 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK77_RS16825 0be359696ead9af5e8b95cc18d5c279d 275 SUPERFAMILY SSF55811 6 58 3.7E-14 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAK77_RS16825 0be359696ead9af5e8b95cc18d5c279d 275 SUPERFAMILY SSF55811 140 197 3.7E-14 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAK77_RS16825 0be359696ead9af5e8b95cc18d5c279d 275 SUPERFAMILY SSF55811 86 97 3.7E-14 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAK77_RS16825 0be359696ead9af5e8b95cc18d5c279d 275 Gene3D G3DSA:3.90.79.10 139 196 2.3E-15 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAK77_RS16825 0be359696ead9af5e8b95cc18d5c279d 275 Gene3D G3DSA:3.90.79.10 8 96 2.3E-15 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAK77_RS09490 03e18bfdf7f3b15ce99d3c8a647c9448 177 PIRSF PIRSF006135 2 175 2.5E-48 T 06-07-2017 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00030+2.7.1.15|KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CAK77_RS09490 03e18bfdf7f3b15ce99d3c8a647c9448 177 Gene3D G3DSA:3.40.50.300 4 173 8.3E-51 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS09490 03e18bfdf7f3b15ce99d3c8a647c9448 177 Pfam PF02283 Cobinamide kinase / cobinamide phosphate guanyltransferase 4 172 8.1E-51 T 06-07-2017 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00030+2.7.1.15|KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CAK77_RS09490 03e18bfdf7f3b15ce99d3c8a647c9448 177 SUPERFAMILY SSF52540 4 173 5.49E-36 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS18040 6e0f4dba3898ae0d3c3e1bb21e3f5109 379 Pfam PF00355 Rieske [2Fe-2S] domain 22 106 7.4E-17 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK77_RS18040 6e0f4dba3898ae0d3c3e1bb21e3f5109 379 SUPERFAMILY SSF50022 17 128 1.13E-28 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK77_RS18040 6e0f4dba3898ae0d3c3e1bb21e3f5109 379 SUPERFAMILY SSF55961 123 340 8.06E-23 T 06-07-2017 CAK77_RS18040 6e0f4dba3898ae0d3c3e1bb21e3f5109 379 Gene3D G3DSA:2.102.10.10 20 135 3.9E-29 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK77_RS05155 b146d55ff67183e26c37cf9ca3fa44ab 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 58 2.3E-13 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS05155 b146d55ff67183e26c37cf9ca3fa44ab 200 SUPERFAMILY SSF46689 4 84 6.16E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS05155 b146d55ff67183e26c37cf9ca3fa44ab 200 Gene3D G3DSA:1.10.357.10 5 182 4.1E-28 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS05155 b146d55ff67183e26c37cf9ca3fa44ab 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 5.8E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS05155 b146d55ff67183e26c37cf9ca3fa44ab 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 5.8E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS03080 de49054b5d76d9d8a09e403832934ed9 321 SUPERFAMILY SSF47203 181 320 1.53E-36 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS03080 de49054b5d76d9d8a09e403832934ed9 321 Gene3D G3DSA:1.20.140.10 182 320 4.4E-36 T 06-07-2017 CAK77_RS03080 de49054b5d76d9d8a09e403832934ed9 321 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 97 4.5E-7 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS03080 de49054b5d76d9d8a09e403832934ed9 321 Gene3D G3DSA:1.10.540.10 2 94 1.4E-7 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS03080 de49054b5d76d9d8a09e403832934ed9 321 SUPERFAMILY SSF56645 3 121 3.66E-10 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK77_RS03080 de49054b5d76d9d8a09e403832934ed9 321 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 180 320 2.4E-29 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS20530 80104018abb05925ab7d77633860a0cd 2581 Pfam PF00668 Condensation domain 1099 1393 4.9E-51 T 06-07-2017 IPR001242 Condensation domain CAK77_RS20530 80104018abb05925ab7d77633860a0cd 2581 Pfam PF00668 Condensation domain 638 914 4.8E-23 T 06-07-2017 IPR001242 Condensation domain CAK77_RS20530 80104018abb05925ab7d77633860a0cd 2581 ProSitePatterns PS00012 Phosphopantetheine attachment site. 563 578 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site CAK77_RS20530 80104018abb05925ab7d77633860a0cd 2581 SUPERFAMILY SSF47336 2047 2121 1.28E-19 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS20530 80104018abb05925ab7d77633860a0cd 2581 Pfam PF00550 Phosphopantetheine attachment site 2057 2120 2.1E-14 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS20530 80104018abb05925ab7d77633860a0cd 2581 Pfam PF00550 Phosphopantetheine attachment site 542 601 4.7E-9 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS20530 80104018abb05925ab7d77633860a0cd 2581 SUPERFAMILY SSF56801 1513 2068 9.68E-147 T 06-07-2017 CAK77_RS20530 80104018abb05925ab7d77633860a0cd 2581 SUPERFAMILY SSF52777 1283 1523 4.45E-50 T 06-07-2017 CAK77_RS20530 80104018abb05925ab7d77633860a0cd 2581 SMART SM01294 2056 2120 3.8E-4 T 06-07-2017 CAK77_RS20530 80104018abb05925ab7d77633860a0cd 2581 ProSitePatterns PS00455 Putative AMP-binding domain signature. 185 196 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK77_RS20530 80104018abb05925ab7d77633860a0cd 2581 Gene3D G3DSA:3.40.50.720 2175 2502 9.6E-29 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS20530 80104018abb05925ab7d77633860a0cd 2581 Pfam PF00501 AMP-binding enzyme 47 434 8.4E-88 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK77_RS20530 80104018abb05925ab7d77633860a0cd 2581 Pfam PF00501 AMP-binding enzyme 1557 1951 2.5E-83 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK77_RS20530 80104018abb05925ab7d77633860a0cd 2581 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 930 1091 8.3E-31 T 06-07-2017 IPR010060 Non-ribosomal peptide synthase CAK77_RS20530 80104018abb05925ab7d77633860a0cd 2581 Gene3D G3DSA:3.40.50.980 1705 1857 2.0E-39 T 06-07-2017 CAK77_RS20530 80104018abb05925ab7d77633860a0cd 2581 Gene3D G3DSA:3.40.50.980 194 346 7.6E-41 T 06-07-2017 CAK77_RS20530 80104018abb05925ab7d77633860a0cd 2581 SUPERFAMILY SSF56801 6 552 9.94E-148 T 06-07-2017 CAK77_RS20530 80104018abb05925ab7d77633860a0cd 2581 SUPERFAMILY SSF51735 2174 2487 1.12E-27 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS20530 80104018abb05925ab7d77633860a0cd 2581 SMART SM00823 Phosphopantetheine attachment site 2055 2124 5.0E-9 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAK77_RS20530 80104018abb05925ab7d77633860a0cd 2581 SMART SM00823 Phosphopantetheine attachment site 539 606 0.1 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAK77_RS20530 80104018abb05925ab7d77633860a0cd 2581 Gene3D G3DSA:1.10.1200.10 543 603 3.4E-24 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS20530 80104018abb05925ab7d77633860a0cd 2581 Gene3D G3DSA:1.10.1200.10 2059 2124 2.8E-25 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS20530 80104018abb05925ab7d77633860a0cd 2581 Gene3D G3DSA:3.40.50.980 41 193 9.0E-46 T 06-07-2017 CAK77_RS20530 80104018abb05925ab7d77633860a0cd 2581 Gene3D G3DSA:2.30.38.10 1858 1929 3.6E-20 T 06-07-2017 CAK77_RS20530 80104018abb05925ab7d77633860a0cd 2581 Gene3D G3DSA:2.30.38.10 347 424 2.4E-22 T 06-07-2017 CAK77_RS20530 80104018abb05925ab7d77633860a0cd 2581 Gene3D G3DSA:3.30.300.30 429 542 1.9E-38 T 06-07-2017 CAK77_RS20530 80104018abb05925ab7d77633860a0cd 2581 Gene3D G3DSA:3.30.300.30 1946 2058 1.1E-39 T 06-07-2017 CAK77_RS20530 80104018abb05925ab7d77633860a0cd 2581 SUPERFAMILY SSF52777 618 783 2.22E-21 T 06-07-2017 CAK77_RS20530 80104018abb05925ab7d77633860a0cd 2581 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1578 1975 9.7E-122 T 06-07-2017 IPR010071 Amino acid adenylation domain CAK77_RS20530 80104018abb05925ab7d77633860a0cd 2581 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 67 458 3.8E-129 T 06-07-2017 IPR010071 Amino acid adenylation domain CAK77_RS20530 80104018abb05925ab7d77633860a0cd 2581 Gene3D G3DSA:3.40.50.980 1552 1704 1.6E-43 T 06-07-2017 CAK77_RS20530 80104018abb05925ab7d77633860a0cd 2581 SUPERFAMILY SSF52777 799 1065 4.11E-23 T 06-07-2017 CAK77_RS20530 80104018abb05925ab7d77633860a0cd 2581 SUPERFAMILY SSF52777 1095 1298 9.67E-38 T 06-07-2017 CAK77_RS20530 80104018abb05925ab7d77633860a0cd 2581 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2079 2094 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site CAK77_RS20530 80104018abb05925ab7d77633860a0cd 2581 TIGRFAM TIGR01746 Thioester-redct: thioester reductase domain 2175 2580 2.5E-95 T 06-07-2017 IPR010080 Thioester reductase-like domain CAK77_RS20530 80104018abb05925ab7d77633860a0cd 2581 SUPERFAMILY SSF47336 531 601 3.93E-16 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS20530 80104018abb05925ab7d77633860a0cd 2581 Pfam PF07993 Male sterility protein 2178 2440 1.5E-61 T 06-07-2017 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 CAK77_RS20530 80104018abb05925ab7d77633860a0cd 2581 Pfam PF13193 AMP-binding enzyme C-terminal domain 442 513 3.7E-9 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAK77_RS20530 80104018abb05925ab7d77633860a0cd 2581 Pfam PF13193 AMP-binding enzyme C-terminal domain 1959 2030 1.2E-10 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAK77_RS06595 2d6df2636ecc10e23ba83f4bf677c3a8 279 SUPERFAMILY SSF102588 3 277 1.23E-71 T 06-07-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CAK77_RS06595 2d6df2636ecc10e23ba83f4bf677c3a8 279 Pfam PF02585 GlcNAc-PI de-N-acetylase 7 156 6.9E-28 T 06-07-2017 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 CAK77_RS06595 2d6df2636ecc10e23ba83f4bf677c3a8 279 Hamap MF_01696 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase [mshB]. 6 277 41.533 T 06-07-2017 IPR017810 Mycothiol biosynthesis protein, MshB GO:0035595 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CAK77_RS06595 2d6df2636ecc10e23ba83f4bf677c3a8 279 TIGRFAM TIGR03445 mycothiol_MshB: N-acetyl-1-D-myo-inositol-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase 7 277 4.2E-120 T 06-07-2017 IPR017810 Mycothiol biosynthesis protein, MshB GO:0035595 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CAK77_RS06595 2d6df2636ecc10e23ba83f4bf677c3a8 279 Gene3D G3DSA:3.40.50.10320 2 278 6.0E-85 T 06-07-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CAK77_RS07200 4dee0c6c7a785434330707f80f102272 355 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 55 68 - T 06-07-2017 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 CAK77_RS07200 4dee0c6c7a785434330707f80f102272 355 Gene3D G3DSA:3.40.50.1100 149 332 1.3E-49 T 06-07-2017 CAK77_RS07200 4dee0c6c7a785434330707f80f102272 355 TIGRFAM TIGR00260 thrC: threonine synthase 12 329 1.8E-92 T 06-07-2017 IPR004450 Threonine synthase-like CAK77_RS07200 4dee0c6c7a785434330707f80f102272 355 PIRSF PIRSF038945 1 354 1.8E-172 T 06-07-2017 IPR026260 Threonine synthase, bacterial/archaeal GO:0004795|GO:0009088 KEGG: 00260+4.2.3.1|KEGG: 00750+4.2.3.1 CAK77_RS07200 4dee0c6c7a785434330707f80f102272 355 SUPERFAMILY SSF53686 8 336 5.37E-101 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAK77_RS07200 4dee0c6c7a785434330707f80f102272 355 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 28 322 1.7E-73 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAK77_RS07200 4dee0c6c7a785434330707f80f102272 355 Gene3D G3DSA:3.40.50.1100 63 148 4.3E-41 T 06-07-2017 CAK77_RS19840 5847b90459d04c5407809ea45a591a8f 376 PRINTS PR00359 B-class P450 signature 316 325 4.6E-47 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS19840 5847b90459d04c5407809ea45a591a8f 376 PRINTS PR00359 B-class P450 signature 119 135 4.6E-47 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS19840 5847b90459d04c5407809ea45a591a8f 376 PRINTS PR00359 B-class P450 signature 249 260 4.6E-47 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS19840 5847b90459d04c5407809ea45a591a8f 376 PRINTS PR00359 B-class P450 signature 295 310 4.6E-47 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS19840 5847b90459d04c5407809ea45a591a8f 376 PRINTS PR00359 B-class P450 signature 267 294 4.6E-47 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS19840 5847b90459d04c5407809ea45a591a8f 376 PRINTS PR00359 B-class P450 signature 72 83 4.6E-47 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS19840 5847b90459d04c5407809ea45a591a8f 376 PRINTS PR00359 B-class P450 signature 172 194 4.6E-47 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS19840 5847b90459d04c5407809ea45a591a8f 376 PRINTS PR00359 B-class P450 signature 136 151 4.6E-47 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS19840 5847b90459d04c5407809ea45a591a8f 376 PRINTS PR00359 B-class P450 signature 325 336 4.6E-47 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS19840 5847b90459d04c5407809ea45a591a8f 376 Pfam PF00067 Cytochrome P450 199 345 2.9E-16 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS19840 5847b90459d04c5407809ea45a591a8f 376 SUPERFAMILY SSF48264 6 376 4.85E-79 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS19840 5847b90459d04c5407809ea45a591a8f 376 PRINTS PR00385 P450 superfamily signature 325 336 7.7E-6 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS19840 5847b90459d04c5407809ea45a591a8f 376 PRINTS PR00385 P450 superfamily signature 249 260 7.7E-6 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS19840 5847b90459d04c5407809ea45a591a8f 376 PRINTS PR00385 P450 superfamily signature 316 325 7.7E-6 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS19840 5847b90459d04c5407809ea45a591a8f 376 PRINTS PR00385 P450 superfamily signature 214 231 7.7E-6 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS19840 5847b90459d04c5407809ea45a591a8f 376 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 318 327 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CAK77_RS19840 5847b90459d04c5407809ea45a591a8f 376 Gene3D G3DSA:1.10.630.10 2 376 9.2E-104 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS17155 c6566ba8ba9ce7bd49d4f79236ff4a1d 275 Pfam PF07313 Protein of unknown function (DUF1460) 69 266 2.3E-64 T 06-07-2017 IPR010846 Protein of unknown function DUF1460 CAK77_RS17155 c6566ba8ba9ce7bd49d4f79236ff4a1d 275 Gene3D G3DSA:1.10.3670.10 41 148 1.4E-34 T 06-07-2017 CAK77_RS17155 c6566ba8ba9ce7bd49d4f79236ff4a1d 275 Gene3D G3DSA:2.30.260.10 149 273 1.8E-25 T 06-07-2017 IPR023360 Putative xylanase-like C-terminal CAK77_RS17155 c6566ba8ba9ce7bd49d4f79236ff4a1d 275 SUPERFAMILY SSF54001 37 274 2.35E-72 T 06-07-2017 CAK77_RS07450 81edf46c35c01dc939d0b5643db26173 225 Gene3D G3DSA:1.20.1540.10 67 204 2.2E-15 T 06-07-2017 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CAK77_RS07450 81edf46c35c01dc939d0b5643db26173 225 Pfam PF01694 Rhomboid family 70 207 2.8E-22 T 06-07-2017 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CAK77_RS07450 81edf46c35c01dc939d0b5643db26173 225 SUPERFAMILY SSF144091 24 208 3.92E-27 T 06-07-2017 CAK77_RS15635 016c4cb0c8412ebdc224b26f364e68d8 652 ProSitePatterns PS00211 ABC transporters family signature. 345 359 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK77_RS15635 016c4cb0c8412ebdc224b26f364e68d8 652 SUPERFAMILY SSF52540 432 651 1.33E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS15635 016c4cb0c8412ebdc224b26f364e68d8 652 Gene3D G3DSA:3.40.50.300 432 652 1.7E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS15635 016c4cb0c8412ebdc224b26f364e68d8 652 Pfam PF00005 ABC transporter 240 372 1.1E-16 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK77_RS15635 016c4cb0c8412ebdc224b26f364e68d8 652 Pfam PF00005 ABC transporter 461 598 2.8E-20 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK77_RS15635 016c4cb0c8412ebdc224b26f364e68d8 652 SUPERFAMILY SSF52540 225 417 6.5E-35 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS15635 016c4cb0c8412ebdc224b26f364e68d8 652 ProSitePatterns PS00211 ABC transporters family signature. 571 585 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK77_RS15635 016c4cb0c8412ebdc224b26f364e68d8 652 SMART SM00382 248 421 4.2E-7 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS15635 016c4cb0c8412ebdc224b26f364e68d8 652 SMART SM00382 470 647 2.2E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS15635 016c4cb0c8412ebdc224b26f364e68d8 652 Gene3D G3DSA:3.40.50.300 225 418 2.7E-37 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS08490 45d372a31c2dbfe179bef056783291ce 381 SUPERFAMILY SSF49493 261 347 3.79E-19 T 06-07-2017 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CAK77_RS08490 45d372a31c2dbfe179bef056783291ce 381 Gene3D G3DSA:1.10.287.110 3 101 3.3E-29 T 06-07-2017 IPR001623 DnaJ domain CAK77_RS08490 45d372a31c2dbfe179bef056783291ce 381 Gene3D G3DSA:2.60.260.20 107 138 2.7E-15 T 06-07-2017 CAK77_RS08490 45d372a31c2dbfe179bef056783291ce 381 Gene3D G3DSA:2.60.260.20 212 256 2.7E-15 T 06-07-2017 CAK77_RS08490 45d372a31c2dbfe179bef056783291ce 381 Pfam PF00684 DnaJ central domain 145 209 7.4E-12 T 06-07-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 CAK77_RS08490 45d372a31c2dbfe179bef056783291ce 381 Pfam PF01556 DnaJ C terminal domain 121 336 4.0E-35 T 06-07-2017 IPR002939 Chaperone DnaJ, C-terminal CAK77_RS08490 45d372a31c2dbfe179bef056783291ce 381 Gene3D G3DSA:2.10.230.10 139 211 1.8E-17 T 06-07-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 CAK77_RS08490 45d372a31c2dbfe179bef056783291ce 381 PRINTS PR00625 DnaJ domain signature 6 24 2.3E-23 T 06-07-2017 IPR001623 DnaJ domain CAK77_RS08490 45d372a31c2dbfe179bef056783291ce 381 PRINTS PR00625 DnaJ domain signature 24 39 2.3E-23 T 06-07-2017 IPR001623 DnaJ domain CAK77_RS08490 45d372a31c2dbfe179bef056783291ce 381 PRINTS PR00625 DnaJ domain signature 40 60 2.3E-23 T 06-07-2017 IPR001623 DnaJ domain CAK77_RS08490 45d372a31c2dbfe179bef056783291ce 381 PRINTS PR00625 DnaJ domain signature 60 79 2.3E-23 T 06-07-2017 IPR001623 DnaJ domain CAK77_RS08490 45d372a31c2dbfe179bef056783291ce 381 Pfam PF00226 DnaJ domain 4 65 2.1E-23 T 06-07-2017 IPR001623 DnaJ domain CAK77_RS08490 45d372a31c2dbfe179bef056783291ce 381 Gene3D G3DSA:2.60.260.20 258 337 2.0E-19 T 06-07-2017 CAK77_RS08490 45d372a31c2dbfe179bef056783291ce 381 SMART SM00271 3 60 4.6E-29 T 06-07-2017 IPR001623 DnaJ domain CAK77_RS08490 45d372a31c2dbfe179bef056783291ce 381 SUPERFAMILY SSF57938 132 212 8.5E-17 T 06-07-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 CAK77_RS08490 45d372a31c2dbfe179bef056783291ce 381 SUPERFAMILY SSF46565 3 102 3.93E-31 T 06-07-2017 IPR001623 DnaJ domain CAK77_RS08490 45d372a31c2dbfe179bef056783291ce 381 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 1 377 36.364 T 06-07-2017 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 CAK77_RS08490 45d372a31c2dbfe179bef056783291ce 381 SUPERFAMILY SSF49493 188 264 2.88E-15 T 06-07-2017 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CAK77_RS08490 45d372a31c2dbfe179bef056783291ce 381 SUPERFAMILY SSF49493 113 136 2.88E-15 T 06-07-2017 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CAK77_RS21990 9801837af80d39c85d4f4c87a1851c86 312 Gene3D G3DSA:3.40.190.10 184 275 4.4E-30 T 06-07-2017 CAK77_RS21990 9801837af80d39c85d4f4c87a1851c86 312 SUPERFAMILY SSF46785 11 117 3.31E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS21990 9801837af80d39c85d4f4c87a1851c86 312 Gene3D G3DSA:3.40.190.10 99 183 9.0E-22 T 06-07-2017 CAK77_RS21990 9801837af80d39c85d4f4c87a1851c86 312 Gene3D G3DSA:1.10.10.10 13 92 4.2E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS21990 9801837af80d39c85d4f4c87a1851c86 312 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 13 68 2.8E-19 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK77_RS21990 9801837af80d39c85d4f4c87a1851c86 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 25 36 1.3E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK77_RS21990 9801837af80d39c85d4f4c87a1851c86 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 46 57 1.3E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK77_RS21990 9801837af80d39c85d4f4c87a1851c86 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 36 46 1.3E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK77_RS21990 9801837af80d39c85d4f4c87a1851c86 312 SUPERFAMILY SSF53850 96 302 1.33E-43 T 06-07-2017 CAK77_RS21990 9801837af80d39c85d4f4c87a1851c86 312 Pfam PF03466 LysR substrate binding domain 95 299 2.6E-48 T 06-07-2017 IPR005119 LysR, substrate-binding CAK77_RS04665 e89fec6275e0e19c603f2771c9515176 439 SUPERFAMILY SSF53383 36 436 1.94E-97 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK77_RS04665 e89fec6275e0e19c603f2771c9515176 439 Gene3D G3DSA:3.90.1150.10 320 436 7.8E-35 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK77_RS04665 e89fec6275e0e19c603f2771c9515176 439 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 248 286 - T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAK77_RS04665 e89fec6275e0e19c603f2771c9515176 439 Pfam PF00202 Aminotransferase class-III 43 435 3.0E-73 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAK77_RS04665 e89fec6275e0e19c603f2771c9515176 439 Gene3D G3DSA:3.40.640.10 76 319 2.8E-60 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK77_RS14250 9b8ca58c803850490924cf2a4b886341 393 Pfam PF07730 Histidine kinase 199 266 5.7E-17 T 06-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CAK77_RS14250 9b8ca58c803850490924cf2a4b886341 393 Gene3D G3DSA:3.30.565.10 307 392 2.9E-8 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS14250 9b8ca58c803850490924cf2a4b886341 393 SUPERFAMILY SSF55874 269 392 7.47E-18 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS14250 9b8ca58c803850490924cf2a4b886341 393 SMART SM00387 304 393 2.4E-4 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS14250 9b8ca58c803850490924cf2a4b886341 393 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 311 392 6.9E-6 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS14250 9b8ca58c803850490924cf2a4b886341 393 PIRSF PIRSF037434 2 393 8.5E-77 T 06-07-2017 IPR017205 Signal transduction histidine kinase, ChrS CAK77_RS01070 7905344fe511d28f5c5d6ce562c08989 517 Gene3D G3DSA:3.90.226.10 5 253 1.7E-62 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS01070 7905344fe511d28f5c5d6ce562c08989 517 SUPERFAMILY SSF52096 9 249 3.52E-66 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS01070 7905344fe511d28f5c5d6ce562c08989 517 Pfam PF01039 Carboxyl transferase domain 34 513 4.3E-139 T 06-07-2017 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAK77_RS01070 7905344fe511d28f5c5d6ce562c08989 517 Gene3D G3DSA:3.90.226.10 264 516 1.1E-74 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS01070 7905344fe511d28f5c5d6ce562c08989 517 SUPERFAMILY SSF52096 223 512 1.38E-76 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS01830 2b197b924b8ca6559a201ee6f23a928b 343 Pfam PF01380 SIS domain 44 166 3.4E-18 T 06-07-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 CAK77_RS01830 2b197b924b8ca6559a201ee6f23a928b 343 Pfam PF01380 SIS domain 202 323 1.4E-13 T 06-07-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 CAK77_RS01830 2b197b924b8ca6559a201ee6f23a928b 343 Gene3D G3DSA:3.40.50.10490 179 341 2.6E-36 T 06-07-2017 CAK77_RS01830 2b197b924b8ca6559a201ee6f23a928b 343 Gene3D G3DSA:3.40.50.10490 4 173 1.8E-35 T 06-07-2017 CAK77_RS01830 2b197b924b8ca6559a201ee6f23a928b 343 SUPERFAMILY SSF53697 6 341 4.95E-78 T 06-07-2017 CAK77_RS18500 41090f038f5efb9f2b844bac8e422ce5 389 Pfam PF04024 PspC domain 24 78 8.6E-13 T 06-07-2017 IPR007168 Phage shock protein, PspC, N-terminal CAK77_RS18500 41090f038f5efb9f2b844bac8e422ce5 389 Pfam PF09922 Cell wall-active antibiotics response 4TMS YvqF 291 363 1.9E-8 T 06-07-2017 IPR024425 Cell wall-active antibiotics response 4TMS YvqF CAK77_RS19215 ff4c7ac644ab445d0a0de79f802767c7 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 06-07-2017 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK77_RS19215 ff4c7ac644ab445d0a0de79f802767c7 156 Gene3D G3DSA:1.10.455.10 10 156 2.8E-63 T 06-07-2017 IPR023798 Ribosomal protein S7 domain CAK77_RS19215 ff4c7ac644ab445d0a0de79f802767c7 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 1.2E-61 T 06-07-2017 IPR023798 Ribosomal protein S7 domain CAK77_RS19215 ff4c7ac644ab445d0a0de79f802767c7 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 35.559 T 06-07-2017 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 CAK77_RS19215 ff4c7ac644ab445d0a0de79f802767c7 156 SUPERFAMILY SSF47973 1 149 9.16E-59 T 06-07-2017 IPR023798 Ribosomal protein S7 domain CAK77_RS19215 ff4c7ac644ab445d0a0de79f802767c7 156 PIRSF PIRSF002122 4 156 2.2E-57 T 06-07-2017 IPR000235 Ribosomal protein S5/S7 GO:0006412 CAK77_RS19215 ff4c7ac644ab445d0a0de79f802767c7 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 2.3E-67 T 06-07-2017 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 CAK77_RS13290 51f76dd2426802cc8232370691c9add5 243 Pfam PF09335 SNARE associated Golgi protein 74 190 1.6E-22 T 06-07-2017 IPR032816 SNARE associated Golgi protein CAK77_RS18660 d2271126ffa53c3468a1f091896a0e0c 477 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 4 200 18.555 T 06-07-2017 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 CAK77_RS18660 d2271126ffa53c3468a1f091896a0e0c 477 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 210 474 19.118 T 06-07-2017 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 CAK77_RS18660 d2271126ffa53c3468a1f091896a0e0c 477 Gene3D G3DSA:3.40.50.10260 2 217 7.0E-52 T 06-07-2017 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 CAK77_RS18660 d2271126ffa53c3468a1f091896a0e0c 477 Pfam PF03853 YjeF-related protein N-terminus 25 182 1.4E-34 T 06-07-2017 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 CAK77_RS18660 d2271126ffa53c3468a1f091896a0e0c 477 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 225 451 6.6E-44 T 06-07-2017 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 CAK77_RS18660 d2271126ffa53c3468a1f091896a0e0c 477 Pfam PF01256 Carbohydrate kinase 234 463 8.3E-61 T 06-07-2017 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 CAK77_RS18660 d2271126ffa53c3468a1f091896a0e0c 477 PIRSF PIRSF017184 3 472 1.9E-88 T 06-07-2017 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 CAK77_RS18660 d2271126ffa53c3468a1f091896a0e0c 477 Gene3D G3DSA:3.40.1190.20 218 475 2.3E-79 T 06-07-2017 IPR029056 Ribokinase-like CAK77_RS18660 d2271126ffa53c3468a1f091896a0e0c 477 SUPERFAMILY SSF64153 4 231 2.22E-45 T 06-07-2017 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 CAK77_RS18660 d2271126ffa53c3468a1f091896a0e0c 477 SUPERFAMILY SSF53613 209 475 1.96E-57 T 06-07-2017 IPR029056 Ribokinase-like CAK77_RS18660 d2271126ffa53c3468a1f091896a0e0c 477 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 411 421 - T 06-07-2017 IPR017953 Carbohydrate kinase, predicted, conserved site CAK77_RS21930 8f35081a6e5d52a3c9f3ec66c0f49fbf 189 Gene3D G3DSA:3.40.630.30 14 189 1.7E-62 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS21930 8f35081a6e5d52a3c9f3ec66c0f49fbf 189 Pfam PF13527 Acetyltransferase (GNAT) domain 34 141 9.7E-10 T 06-07-2017 CAK77_RS21930 8f35081a6e5d52a3c9f3ec66c0f49fbf 189 SUPERFAMILY SSF55729 21 189 7.8E-33 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS10630 2328a7a288e53516c2e0e411c82ca9de 452 PIRSF PIRSF018077 1 452 4.7E-185 T 06-07-2017 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 CAK77_RS10630 2328a7a288e53516c2e0e411c82ca9de 452 Pfam PF03136 Pup-ligase protein 4 422 5.7E-160 T 06-07-2017 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 CAK77_RS10630 2328a7a288e53516c2e0e411c82ca9de 452 TIGRFAM TIGR03686 pupylate_PafA: Pup--protein ligase 3 452 9.9E-241 T 06-07-2017 IPR022279 Pup--protein ligase GO:0010498|GO:0016879|GO:0019941 CAK77_RS10630 2328a7a288e53516c2e0e411c82ca9de 452 Hamap MF_02111 Pup--protein ligase [pafA]. 1 452 50.691 T 06-07-2017 IPR022279 Pup--protein ligase GO:0010498|GO:0016879|GO:0019941 CAK77_RS00395 9d7e02a95b44c77b1cd93c491b9146df 102 ProDom PD195452 PE FAMILY PRECURSOR PE-FAMILY SIGNAL PE15 PE_1 47 100 2.0E-12 T 06-07-2017 CAK77_RS00395 9d7e02a95b44c77b1cd93c491b9146df 102 Pfam PF00934 PE family 3 91 2.4E-20 T 06-07-2017 IPR000084 PE-PGRS family, N-terminal CAK77_RS00395 9d7e02a95b44c77b1cd93c491b9146df 102 SUPERFAMILY SSF140459 7 73 1.49E-12 T 06-07-2017 CAK77_RS10875 9d7e02a95b44c77b1cd93c491b9146df 102 ProDom PD195452 PE FAMILY PRECURSOR PE-FAMILY SIGNAL PE15 PE_1 47 100 2.0E-12 T 06-07-2017 CAK77_RS10875 9d7e02a95b44c77b1cd93c491b9146df 102 Pfam PF00934 PE family 3 91 2.4E-20 T 06-07-2017 IPR000084 PE-PGRS family, N-terminal CAK77_RS10875 9d7e02a95b44c77b1cd93c491b9146df 102 SUPERFAMILY SSF140459 7 73 1.49E-12 T 06-07-2017 CAK77_RS12830 92dee6ee6ad61bfd81e70204787ac2a3 550 Gene3D G3DSA:3.40.50.980 162 315 1.8E-25 T 06-07-2017 CAK77_RS12830 92dee6ee6ad61bfd81e70204787ac2a3 550 Gene3D G3DSA:3.30.300.30 407 500 2.1E-18 T 06-07-2017 CAK77_RS12830 92dee6ee6ad61bfd81e70204787ac2a3 550 ProSitePatterns PS00455 Putative AMP-binding domain signature. 155 166 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK77_RS12830 92dee6ee6ad61bfd81e70204787ac2a3 550 Gene3D G3DSA:2.30.38.10 316 401 1.5E-17 T 06-07-2017 CAK77_RS12830 92dee6ee6ad61bfd81e70204787ac2a3 550 Pfam PF00501 AMP-binding enzyme 12 406 8.7E-57 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK77_RS12830 92dee6ee6ad61bfd81e70204787ac2a3 550 Gene3D G3DSA:3.40.50.980 11 161 1.8E-21 T 06-07-2017 CAK77_RS12830 92dee6ee6ad61bfd81e70204787ac2a3 550 SUPERFAMILY SSF56801 11 507 4.32E-95 T 06-07-2017 CAK77_RS12830 92dee6ee6ad61bfd81e70204787ac2a3 550 Pfam PF13193 AMP-binding enzyme C-terminal domain 417 491 5.0E-9 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAK77_RS00995 495e65d729b28650daccf0fce7132112 254 SMART SM00563 37 151 2.1E-33 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CAK77_RS00995 495e65d729b28650daccf0fce7132112 254 Gene3D G3DSA:3.40.1130.10 19 193 8.0E-19 T 06-07-2017 CAK77_RS00995 495e65d729b28650daccf0fce7132112 254 SUPERFAMILY SSF69593 17 210 8.89E-30 T 06-07-2017 CAK77_RS00995 495e65d729b28650daccf0fce7132112 254 Pfam PF01553 Acyltransferase 22 148 1.8E-29 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CAK77_RS17085 015be7517057e573b25c3044e1a7ca25 183 Gene3D G3DSA:1.10.1740.10 6 113 7.7E-25 T 06-07-2017 CAK77_RS17085 015be7517057e573b25c3044e1a7ca25 183 SUPERFAMILY SSF88659 114 173 7.2E-13 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS17085 015be7517057e573b25c3044e1a7ca25 183 Pfam PF08281 Sigma-70, region 4 121 172 1.9E-13 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS17085 015be7517057e573b25c3044e1a7ca25 183 SUPERFAMILY SSF88946 6 106 4.71E-23 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS17085 015be7517057e573b25c3044e1a7ca25 183 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 49 80 - T 06-07-2017 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS17085 015be7517057e573b25c3044e1a7ca25 183 Pfam PF04542 Sigma-70 region 2 28 93 2.7E-13 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS17085 015be7517057e573b25c3044e1a7ca25 183 Gene3D G3DSA:1.10.10.10 117 172 6.0E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS17085 015be7517057e573b25c3044e1a7ca25 183 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 24 172 1.3E-23 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS07815 528ce32d9f48900c05ffbeffa13714a3 787 Pfam PF09371 Tex-like protein N-terminal domain 14 193 4.1E-68 T 06-07-2017 IPR018974 Tex-like protein, N-terminal CAK77_RS07815 528ce32d9f48900c05ffbeffa13714a3 787 Gene3D G3DSA:1.10.150.310 503 634 5.3E-43 T 06-07-2017 IPR023097 Tex RuvX-like domain CAK77_RS07815 528ce32d9f48900c05ffbeffa13714a3 787 SUPERFAMILY SSF47781 474 562 1.05E-25 T 06-07-2017 IPR010994 RuvA domain 2-like CAK77_RS07815 528ce32d9f48900c05ffbeffa13714a3 787 Gene3D G3DSA:3.30.420.140 326 454 4.1E-51 T 06-07-2017 IPR006641 YqgF/RNase H-like domain GO:0006139 CAK77_RS07815 528ce32d9f48900c05ffbeffa13714a3 787 SUPERFAMILY SSF47781 564 635 2.07E-19 T 06-07-2017 IPR010994 RuvA domain 2-like CAK77_RS07815 528ce32d9f48900c05ffbeffa13714a3 787 Pfam PF12836 Helix-hairpin-helix motif 495 559 3.9E-27 T 06-07-2017 CAK77_RS07815 528ce32d9f48900c05ffbeffa13714a3 787 Gene3D G3DSA:2.40.50.140 644 724 2.8E-26 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS07815 528ce32d9f48900c05ffbeffa13714a3 787 SUPERFAMILY SSF50249 643 730 2.76E-23 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS07815 528ce32d9f48900c05ffbeffa13714a3 787 Gene3D G3DSA:1.10.3500.10 115 322 2.2E-87 T 06-07-2017 IPR023323 Tex-like domain CAK77_RS07815 528ce32d9f48900c05ffbeffa13714a3 787 Gene3D G3DSA:1.10.3500.10 455 502 2.2E-87 T 06-07-2017 IPR023323 Tex-like domain CAK77_RS07815 528ce32d9f48900c05ffbeffa13714a3 787 Pfam PF16921 Tex protein YqgF-like domain 327 455 2.5E-51 T 06-07-2017 IPR032639 Tex protein, YqgF-like domain CAK77_RS07815 528ce32d9f48900c05ffbeffa13714a3 787 SMART SM00732 326 428 2.8E-35 T 06-07-2017 IPR006641 YqgF/RNase H-like domain GO:0006139 CAK77_RS07815 528ce32d9f48900c05ffbeffa13714a3 787 Pfam PF00575 S1 RNA binding domain 652 724 1.6E-18 T 06-07-2017 IPR003029 S1 domain GO:0003676 CAK77_RS07815 528ce32d9f48900c05ffbeffa13714a3 787 Gene3D G3DSA:1.10.10.650 6 114 2.3E-45 T 06-07-2017 IPR023319 Tex-like protein, HTH domain CAK77_RS07815 528ce32d9f48900c05ffbeffa13714a3 787 SMART SM00316 653 724 6.9E-23 T 06-07-2017 IPR022967 RNA-binding domain, S1 CAK77_RS07815 528ce32d9f48900c05ffbeffa13714a3 787 SUPERFAMILY SSF158832 7 321 4.45E-106 T 06-07-2017 CAK77_RS07815 528ce32d9f48900c05ffbeffa13714a3 787 SUPERFAMILY SSF53098 322 473 1.37E-48 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAK77_RS13175 aaaa207e9a4082e18183f26d29d5e19e 383 Gene3D G3DSA:3.90.1150.10 271 374 6.0E-14 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK77_RS13175 aaaa207e9a4082e18183f26d29d5e19e 383 Gene3D G3DSA:3.40.640.10 54 270 3.0E-79 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK77_RS13175 aaaa207e9a4082e18183f26d29d5e19e 383 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 233 242 - T 06-07-2017 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 CAK77_RS13175 aaaa207e9a4082e18183f26d29d5e19e 383 SUPERFAMILY SSF53383 24 378 7.93E-96 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK77_RS13175 aaaa207e9a4082e18183f26d29d5e19e 383 Pfam PF00155 Aminotransferase class I and II 38 373 1.9E-59 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAK77_RS14870 124ad175d4b4232a36e86f8b27420f24 229 Gene3D G3DSA:3.30.559.10 12 221 8.5E-73 T 06-07-2017 IPR023213 Chloramphenicol acetyltransferase-like domain Reactome: R-HSA-389661 CAK77_RS14870 124ad175d4b4232a36e86f8b27420f24 229 ProDom PD002660 TRANSFERASE CHLORAMPHENICOL ACYLTRANSFERASE ACETYLTRANSFERASE ANTIBIOTIC RESISTANCE PLASMID CAT O-ACETYLTRANSFERASE DIRECT 24 217 2.0E-62 T 06-07-2017 IPR001707 Chloramphenicol acetyltransferase GO:0008811 CAK77_RS14870 124ad175d4b4232a36e86f8b27420f24 229 ProSitePatterns PS00100 Chloramphenicol acetyltransferase active site. 199 209 - T 06-07-2017 IPR018372 Chloramphenicol acetyltransferase, active site GO:0008811 CAK77_RS14870 124ad175d4b4232a36e86f8b27420f24 229 SMART SM01059 13 218 4.9E-77 T 06-07-2017 IPR001707 Chloramphenicol acetyltransferase GO:0008811 CAK77_RS14870 124ad175d4b4232a36e86f8b27420f24 229 SUPERFAMILY SSF52777 13 225 1.67E-65 T 06-07-2017 CAK77_RS14870 124ad175d4b4232a36e86f8b27420f24 229 PIRSF PIRSF000440 11 227 6.2E-72 T 06-07-2017 IPR001707 Chloramphenicol acetyltransferase GO:0008811 CAK77_RS14870 124ad175d4b4232a36e86f8b27420f24 229 Pfam PF00302 Chloramphenicol acetyltransferase 13 218 1.0E-79 T 06-07-2017 IPR001707 Chloramphenicol acetyltransferase GO:0008811 CAK77_RS23900 120572e7f90e35ca9300b96808e660f2 292 TIGRFAM TIGR03560 F420_Rv1855c: probable F420-dependent oxidoreductase, Rv1855c family 3 233 7.7E-85 T 06-07-2017 IPR019952 F420-dependent oxidoreductase-predicted, Rv1855c CAK77_RS23900 120572e7f90e35ca9300b96808e660f2 292 Pfam PF00296 Luciferase-like monooxygenase 8 238 5.4E-43 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS23900 120572e7f90e35ca9300b96808e660f2 292 SUPERFAMILY SSF51679 2 238 1.07E-56 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS23900 120572e7f90e35ca9300b96808e660f2 292 Gene3D G3DSA:3.20.20.30 1 254 4.0E-63 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS14795 46dc9b5845694c8f0354565a3120ca0e 348 Gene3D G3DSA:3.40.50.300 24 204 2.0E-23 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS14795 46dc9b5845694c8f0354565a3120ca0e 348 SUPERFAMILY SSF52540 70 294 3.08E-11 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS14795 46dc9b5845694c8f0354565a3120ca0e 348 Pfam PF03969 AFG1-like ATPase 232 341 2.4E-22 T 06-07-2017 IPR005654 ATPase, AFG1-like GO:0005524 CAK77_RS14795 46dc9b5845694c8f0354565a3120ca0e 348 Pfam PF03969 AFG1-like ATPase 21 227 2.6E-56 T 06-07-2017 IPR005654 ATPase, AFG1-like GO:0005524 CAK77_RS16270 fd64803e6874d9a6073f0990e27ae6db 189 SMART SM00756 4 145 2.2E-57 T 06-07-2017 IPR012932 Vitamin K epoxide reductase Reactome: R-HSA-6806664 CAK77_RS16270 fd64803e6874d9a6073f0990e27ae6db 189 Pfam PF07884 Vitamin K epoxide reductase family 10 141 1.6E-32 T 06-07-2017 IPR012932 Vitamin K epoxide reductase Reactome: R-HSA-6806664 CAK77_RS17945 94448ffba709405ee0cd43fdebaf6f71 361 TIGRFAM TIGR01819 F420_cofD: 2-phospho-L-lactate transferase 42 354 4.4E-122 T 06-07-2017 IPR010115 2-phospho-L-lactate transferase GO:0000287|GO:0016780|GO:0051188 KEGG: 00680+2.7.8.28|MetaCyc: PWY-5198 CAK77_RS17945 94448ffba709405ee0cd43fdebaf6f71 361 Pfam PF01933 Uncharacterised protein family UPF0052 42 324 1.2E-63 T 06-07-2017 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 CAK77_RS17945 94448ffba709405ee0cd43fdebaf6f71 361 Gene3D G3DSA:3.40.50.10680 130 358 3.9E-74 T 06-07-2017 CAK77_RS17945 94448ffba709405ee0cd43fdebaf6f71 361 SUPERFAMILY SSF142338 42 357 1.7E-79 T 06-07-2017 CAK77_RS17945 94448ffba709405ee0cd43fdebaf6f71 361 Hamap MF_01257 2-phospho-L-lactate transferase [cofD]. 1 361 152.38 T 06-07-2017 IPR010115 2-phospho-L-lactate transferase GO:0000287|GO:0016780|GO:0051188 KEGG: 00680+2.7.8.28|MetaCyc: PWY-5198 CAK77_RS07930 9543012a1769f7eba88c95dc1042ca63 205 SUPERFAMILY SSF52833 10 164 6.71E-23 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK77_RS07930 9543012a1769f7eba88c95dc1042ca63 205 Pfam PF01323 DSBA-like thioredoxin domain 10 163 2.0E-12 T 06-07-2017 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 CAK77_RS07930 9543012a1769f7eba88c95dc1042ca63 205 Gene3D G3DSA:3.40.30.10 10 163 1.3E-12 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK77_RS19150 f154798dc1fa35b274f8b3901c0195e3 198 Gene3D G3DSA:1.10.357.10 60 191 1.8E-43 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS19150 f154798dc1fa35b274f8b3901c0195e3 198 SUPERFAMILY SSF46689 6 85 1.75E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS19150 f154798dc1fa35b274f8b3901c0195e3 198 TIGRFAM TIGR03968 mycofact_TetR: mycofactocin system transcriptional regulator 7 194 8.1E-90 T 06-07-2017 IPR023851 Transcriptional regulator, TetR-type CAK77_RS19150 f154798dc1fa35b274f8b3901c0195e3 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 62 8.7E-15 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS19150 f154798dc1fa35b274f8b3901c0195e3 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 1.7E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS19150 f154798dc1fa35b274f8b3901c0195e3 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 1.7E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS19150 f154798dc1fa35b274f8b3901c0195e3 198 Gene3D G3DSA:1.10.10.60 6 59 5.7E-19 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS05465 1152c3640b1419520f81a9043e12ff9f 435 SUPERFAMILY SSF53218 201 347 6.81E-30 T 06-07-2017 IPR001453 MoaB/Mog domain CAK77_RS05465 1152c3640b1419520f81a9043e12ff9f 435 Pfam PF03453 MoeA N-terminal region (domain I and II) 3 191 2.0E-28 T 06-07-2017 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 CAK77_RS05465 1152c3640b1419520f81a9043e12ff9f 435 SMART SM00852 204 343 9.5E-23 T 06-07-2017 IPR001453 MoaB/Mog domain CAK77_RS05465 1152c3640b1419520f81a9043e12ff9f 435 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 201 339 1.1E-25 T 06-07-2017 IPR001453 MoaB/Mog domain CAK77_RS05465 1152c3640b1419520f81a9043e12ff9f 435 Pfam PF00994 Probable molybdopterin binding domain 205 342 6.6E-18 T 06-07-2017 IPR001453 MoaB/Mog domain CAK77_RS05465 1152c3640b1419520f81a9043e12ff9f 435 SUPERFAMILY SSF63882 94 200 8.11E-38 T 06-07-2017 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 CAK77_RS05465 1152c3640b1419520f81a9043e12ff9f 435 SUPERFAMILY SSF63882 2 61 8.11E-38 T 06-07-2017 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 CAK77_RS05465 1152c3640b1419520f81a9043e12ff9f 435 Gene3D G3DSA:3.90.105.10 155 186 1.0E-17 T 06-07-2017 CAK77_RS05465 1152c3640b1419520f81a9043e12ff9f 435 SUPERFAMILY SSF63867 353 431 1.7E-15 T 06-07-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 CAK77_RS05465 1152c3640b1419520f81a9043e12ff9f 435 Gene3D G3DSA:2.40.340.10 357 428 3.2E-19 T 06-07-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 CAK77_RS05465 1152c3640b1419520f81a9043e12ff9f 435 Pfam PF03454 MoeA C-terminal region (domain IV) 356 431 1.3E-17 T 06-07-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 CAK77_RS05465 1152c3640b1419520f81a9043e12ff9f 435 Gene3D G3DSA:3.40.980.10 187 356 4.2E-48 T 06-07-2017 IPR001453 MoaB/Mog domain CAK77_RS05465 1152c3640b1419520f81a9043e12ff9f 435 Gene3D G3DSA:2.170.190.11 44 154 6.9E-30 T 06-07-2017 CAK77_RS10960 76f9ce5243cc409352c185042a00c7dc 1458 Gene3D G3DSA:3.30.300.30 837 954 3.4E-33 T 06-07-2017 CAK77_RS10960 76f9ce5243cc409352c185042a00c7dc 1458 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 480 866 3.4E-120 T 06-07-2017 IPR010071 Amino acid adenylation domain CAK77_RS10960 76f9ce5243cc409352c185042a00c7dc 1458 Pfam PF00668 Condensation domain 27 308 2.3E-35 T 06-07-2017 IPR001242 Condensation domain CAK77_RS10960 76f9ce5243cc409352c185042a00c7dc 1458 Pfam PF00668 Condensation domain 1055 1282 2.0E-12 T 06-07-2017 IPR001242 Condensation domain CAK77_RS10960 76f9ce5243cc409352c185042a00c7dc 1458 SUPERFAMILY SSF56801 419 962 1.2E-150 T 06-07-2017 CAK77_RS10960 76f9ce5243cc409352c185042a00c7dc 1458 ProSitePatterns PS00455 Putative AMP-binding domain signature. 587 598 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK77_RS10960 76f9ce5243cc409352c185042a00c7dc 1458 Pfam PF00501 AMP-binding enzyme 460 842 3.2E-94 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK77_RS10960 76f9ce5243cc409352c185042a00c7dc 1458 Gene3D G3DSA:3.40.50.980 596 754 5.2E-39 T 06-07-2017 CAK77_RS10960 76f9ce5243cc409352c185042a00c7dc 1458 Pfam PF13193 AMP-binding enzyme C-terminal domain 850 925 3.0E-7 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAK77_RS10960 76f9ce5243cc409352c185042a00c7dc 1458 SUPERFAMILY SSF52777 198 423 2.33E-36 T 06-07-2017 CAK77_RS10960 76f9ce5243cc409352c185042a00c7dc 1458 Gene3D G3DSA:2.30.38.10 755 832 4.5E-26 T 06-07-2017 CAK77_RS10960 76f9ce5243cc409352c185042a00c7dc 1458 SUPERFAMILY SSF52777 1033 1219 1.45E-22 T 06-07-2017 CAK77_RS10960 76f9ce5243cc409352c185042a00c7dc 1458 Gene3D G3DSA:3.40.50.980 453 595 6.9E-50 T 06-07-2017 CAK77_RS10960 76f9ce5243cc409352c185042a00c7dc 1458 Pfam PF00550 Phosphopantetheine attachment site 953 1015 1.3E-7 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS10960 76f9ce5243cc409352c185042a00c7dc 1458 SUPERFAMILY SSF52777 1209 1455 1.45E-10 T 06-07-2017 CAK77_RS10960 76f9ce5243cc409352c185042a00c7dc 1458 SUPERFAMILY SSF52777 26 209 1.33E-30 T 06-07-2017 CAK77_RS10960 76f9ce5243cc409352c185042a00c7dc 1458 Gene3D G3DSA:1.10.1200.10 955 1019 3.8E-18 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS10960 76f9ce5243cc409352c185042a00c7dc 1458 SUPERFAMILY SSF47336 944 1016 1.27E-12 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS10960 76f9ce5243cc409352c185042a00c7dc 1458 SMART SM00823 Phosphopantetheine attachment site 950 1019 0.0046 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAK77_RS15340 166da93fa0494c2fde1a79dbf9c26aa5 272 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 94 105 1.7E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS15340 166da93fa0494c2fde1a79dbf9c26aa5 272 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 154 1.7E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS15340 166da93fa0494c2fde1a79dbf9c26aa5 272 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 170 189 1.7E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS15340 166da93fa0494c2fde1a79dbf9c26aa5 272 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 269 3.5E-47 T 06-07-2017 CAK77_RS15340 166da93fa0494c2fde1a79dbf9c26aa5 272 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 157 185 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK77_RS15340 166da93fa0494c2fde1a79dbf9c26aa5 272 SUPERFAMILY SSF51735 1 269 5.85E-66 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS15340 166da93fa0494c2fde1a79dbf9c26aa5 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 6.9E-31 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS15340 166da93fa0494c2fde1a79dbf9c26aa5 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 189 6.9E-31 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS15340 166da93fa0494c2fde1a79dbf9c26aa5 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 232 252 6.9E-31 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS15340 166da93fa0494c2fde1a79dbf9c26aa5 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 94 105 6.9E-31 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS15340 166da93fa0494c2fde1a79dbf9c26aa5 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 156 6.9E-31 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS15340 166da93fa0494c2fde1a79dbf9c26aa5 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 191 208 6.9E-31 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS15340 166da93fa0494c2fde1a79dbf9c26aa5 272 TIGRFAM TIGR03971 SDR_subfam_1: SDR family mycofactocin-dependent oxidoreductase 4 270 2.9E-110 T 06-07-2017 IPR023985 Mycofactocin-dependent oxidoreductase CAK77_RS15340 166da93fa0494c2fde1a79dbf9c26aa5 272 Gene3D G3DSA:3.40.50.720 1 269 1.7E-75 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS16205 f372335bbb252343fe6c267d43562d3b 258 Hamap MF_00104 Ribonuclease 3 [rnc]. 12 228 28.929 T 06-07-2017 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 CAK77_RS16205 f372335bbb252343fe6c267d43562d3b 258 SMART SM00358 166 232 5.2E-22 T 06-07-2017 IPR014720 Double-stranded RNA-binding domain CAK77_RS16205 f372335bbb252343fe6c267d43562d3b 258 SUPERFAMILY SSF54768 120 232 1.05E-25 T 06-07-2017 CAK77_RS16205 f372335bbb252343fe6c267d43562d3b 258 ProSitePatterns PS00517 Ribonuclease III family signature. 45 53 - T 06-07-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CAK77_RS16205 f372335bbb252343fe6c267d43562d3b 258 SMART SM00535 23 159 1.8E-52 T 06-07-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CAK77_RS16205 f372335bbb252343fe6c267d43562d3b 258 Pfam PF14622 Ribonuclease-III-like 22 148 1.9E-35 T 06-07-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CAK77_RS16205 f372335bbb252343fe6c267d43562d3b 258 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 22 229 1.7E-69 T 06-07-2017 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 CAK77_RS16205 f372335bbb252343fe6c267d43562d3b 258 Pfam PF00035 Double-stranded RNA binding motif 166 229 8.5E-16 T 06-07-2017 IPR014720 Double-stranded RNA-binding domain CAK77_RS16205 f372335bbb252343fe6c267d43562d3b 258 Gene3D G3DSA:1.10.1520.10 15 155 4.1E-40 T 06-07-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CAK77_RS16205 f372335bbb252343fe6c267d43562d3b 258 SUPERFAMILY SSF69065 21 167 1.2E-41 T 06-07-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CAK77_RS16205 f372335bbb252343fe6c267d43562d3b 258 Gene3D G3DSA:3.30.160.20 164 230 7.6E-25 T 06-07-2017 IPR014720 Double-stranded RNA-binding domain CAK77_RS13030 f0728ac9820e79da8b51b181bdb79017 163 Pfam PF12802 MarR family 54 109 8.8E-15 T 06-07-2017 CAK77_RS13030 f0728ac9820e79da8b51b181bdb79017 163 SUPERFAMILY SSF46785 10 157 2.32E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS13030 f0728ac9820e79da8b51b181bdb79017 163 SMART SM00347 44 145 7.6E-16 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK77_RS13030 f0728ac9820e79da8b51b181bdb79017 163 Gene3D G3DSA:1.10.10.10 14 160 8.4E-33 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS13030 f0728ac9820e79da8b51b181bdb79017 163 PRINTS PR00598 Bacterial regulatory protein MarR family signature 86 101 9.3E-7 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK77_RS13030 f0728ac9820e79da8b51b181bdb79017 163 PRINTS PR00598 Bacterial regulatory protein MarR family signature 105 121 9.3E-7 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK77_RS00800 01f9fbb924de2f2b06f0117f3a85b62e 185 Gene3D G3DSA:1.20.1260.10 11 164 2.0E-43 T 06-07-2017 IPR012347 Ferritin-related CAK77_RS00800 01f9fbb924de2f2b06f0117f3a85b62e 185 SUPERFAMILY SSF47240 12 157 2.44E-42 T 06-07-2017 IPR009078 Ferritin-like superfamily CAK77_RS00800 01f9fbb924de2f2b06f0117f3a85b62e 185 Pfam PF00210 Ferritin-like domain 16 151 2.7E-32 T 06-07-2017 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 CAK77_RS01605 600f6ca83f750e437fbf4af0998c5491 397 Gene3D G3DSA:1.20.140.10 206 392 1.1E-40 T 06-07-2017 CAK77_RS01605 600f6ca83f750e437fbf4af0998c5491 397 SUPERFAMILY SSF47203 245 391 5.8E-13 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS01605 600f6ca83f750e437fbf4af0998c5491 397 Gene3D G3DSA:2.40.110.10 121 205 4.3E-25 T 06-07-2017 CAK77_RS01605 600f6ca83f750e437fbf4af0998c5491 397 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 15 87 5.9E-6 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS01605 600f6ca83f750e437fbf4af0998c5491 397 SUPERFAMILY SSF56645 15 210 8.12E-32 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK77_RS01605 600f6ca83f750e437fbf4af0998c5491 397 Gene3D G3DSA:1.10.540.10 5 109 1.0E-35 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS01605 600f6ca83f750e437fbf4af0998c5491 397 PIRSF PIRSF016578 1 396 7.0E-120 T 06-07-2017 CAK77_RS01605 600f6ca83f750e437fbf4af0998c5491 397 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 245 375 1.7E-29 T 06-07-2017 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain CAK77_RS03055 2e51be34a1b2c9c43dda25b41f90e31d 252 Gene3D G3DSA:1.20.1080.10 5 241 1.2E-66 T 06-07-2017 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CAK77_RS03055 2e51be34a1b2c9c43dda25b41f90e31d 252 Pfam PF00230 Major intrinsic protein 4 236 8.7E-48 T 06-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CAK77_RS03055 2e51be34a1b2c9c43dda25b41f90e31d 252 ProSitePatterns PS00221 MIP family signature. 75 83 - T 06-07-2017 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CAK77_RS03055 2e51be34a1b2c9c43dda25b41f90e31d 252 SUPERFAMILY SSF81338 7 241 2.88E-61 T 06-07-2017 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CAK77_RS03055 2e51be34a1b2c9c43dda25b41f90e31d 252 PRINTS PR00783 Major intrinsic protein family signature 6 25 1.7E-49 T 06-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CAK77_RS03055 2e51be34a1b2c9c43dda25b41f90e31d 252 PRINTS PR00783 Major intrinsic protein family signature 57 81 1.7E-49 T 06-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CAK77_RS03055 2e51be34a1b2c9c43dda25b41f90e31d 252 PRINTS PR00783 Major intrinsic protein family signature 180 202 1.7E-49 T 06-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CAK77_RS03055 2e51be34a1b2c9c43dda25b41f90e31d 252 PRINTS PR00783 Major intrinsic protein family signature 150 168 1.7E-49 T 06-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CAK77_RS03055 2e51be34a1b2c9c43dda25b41f90e31d 252 PRINTS PR00783 Major intrinsic protein family signature 94 113 1.7E-49 T 06-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CAK77_RS03055 2e51be34a1b2c9c43dda25b41f90e31d 252 PRINTS PR00783 Major intrinsic protein family signature 219 239 1.7E-49 T 06-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CAK77_RS03055 2e51be34a1b2c9c43dda25b41f90e31d 252 TIGRFAM TIGR00861 MIP: MIP family channel proteins 10 236 4.8E-56 T 06-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CAK77_RS12820 ce688ee6882d766c3843ee6864ed2b2b 440 Pfam PF00743 Flavin-binding monooxygenase-like 6 424 9.6E-78 T 06-07-2017 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 CAK77_RS12820 ce688ee6882d766c3843ee6864ed2b2b 440 SUPERFAMILY SSF51905 2 218 7.77E-46 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS12820 ce688ee6882d766c3843ee6864ed2b2b 440 Gene3D G3DSA:3.50.50.60 295 424 2.8E-18 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS12820 ce688ee6882d766c3843ee6864ed2b2b 440 PIRSF PIRSF000332 3 427 1.8E-87 T 06-07-2017 IPR012143 Dimethylaniline monooxygenase, N-oxide-forming GO:0004499|GO:0050660|GO:0050661|GO:0055114 KEGG: 00982+1.14.13.8 CAK77_RS12820 ce688ee6882d766c3843ee6864ed2b2b 440 SUPERFAMILY SSF51905 296 420 1.94E-7 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS12820 ce688ee6882d766c3843ee6864ed2b2b 440 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 4 20 7.0E-33 T 06-07-2017 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 CAK77_RS12820 ce688ee6882d766c3843ee6864ed2b2b 440 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 302 329 7.0E-33 T 06-07-2017 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 CAK77_RS12820 ce688ee6882d766c3843ee6864ed2b2b 440 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 78 93 7.0E-33 T 06-07-2017 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 CAK77_RS12820 ce688ee6882d766c3843ee6864ed2b2b 440 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 348 365 7.0E-33 T 06-07-2017 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 CAK77_RS12820 ce688ee6882d766c3843ee6864ed2b2b 440 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 132 148 7.0E-33 T 06-07-2017 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 CAK77_RS12820 ce688ee6882d766c3843ee6864ed2b2b 440 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 28 52 7.0E-33 T 06-07-2017 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 CAK77_RS12820 ce688ee6882d766c3843ee6864ed2b2b 440 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 189 204 7.0E-33 T 06-07-2017 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 CAK77_RS12820 ce688ee6882d766c3843ee6864ed2b2b 440 Gene3D G3DSA:3.50.50.60 6 214 8.2E-47 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS18780 2cb0dd3614fa0a1fdd9a925d12472c38 208 SMART SM01110 42 208 1.1E-53 T 06-07-2017 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 CAK77_RS18780 2cb0dd3614fa0a1fdd9a925d12472c38 208 Pfam PF01083 Cutinase 43 208 5.7E-36 T 06-07-2017 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 CAK77_RS18780 2cb0dd3614fa0a1fdd9a925d12472c38 208 PRINTS PR00129 Cutinase signature 109 128 7.3E-5 T 06-07-2017 IPR011150 Cutinase, monofunctional GO:0005576|GO:0050525 CAK77_RS18780 2cb0dd3614fa0a1fdd9a925d12472c38 208 PRINTS PR00129 Cutinase signature 169 194 7.3E-5 T 06-07-2017 IPR011150 Cutinase, monofunctional GO:0005576|GO:0050525 CAK77_RS18780 2cb0dd3614fa0a1fdd9a925d12472c38 208 SUPERFAMILY SSF53474 43 207 1.67E-33 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS18780 2cb0dd3614fa0a1fdd9a925d12472c38 208 Gene3D G3DSA:3.40.50.1820 35 208 2.6E-46 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS17825 a0810969ab462b8e6e57ae4810e92c02 230 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 61 1.1E-16 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS17825 a0810969ab462b8e6e57ae4810e92c02 230 SUPERFAMILY SSF46689 4 80 2.41E-19 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS17825 a0810969ab462b8e6e57ae4810e92c02 230 Gene3D G3DSA:1.10.357.10 6 186 2.2E-32 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS17825 a0810969ab462b8e6e57ae4810e92c02 230 SUPERFAMILY SSF48498 105 203 2.3E-6 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS17825 a0810969ab462b8e6e57ae4810e92c02 230 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 2.5E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS17825 a0810969ab462b8e6e57ae4810e92c02 230 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 2.5E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS14235 622b3aa7495f3482afa0e45e10a16ec0 129 Pfam PF01042 Endoribonuclease L-PSP 8 123 3.8E-32 T 06-07-2017 IPR006175 YjgF/YER057c/UK114 family CAK77_RS14235 622b3aa7495f3482afa0e45e10a16ec0 129 SUPERFAMILY SSF55298 2 124 2.36E-38 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAK77_RS14235 622b3aa7495f3482afa0e45e10a16ec0 129 Gene3D G3DSA:3.30.1330.40 5 124 2.5E-38 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAK77_RS14235 622b3aa7495f3482afa0e45e10a16ec0 129 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 4 122 1.7E-34 T 06-07-2017 IPR006056 RidA family CAK77_RS02315 c8ecc545877404e92b23c1fe5ca685b5 265 Gene3D G3DSA:1.10.340.30 53 153 6.5E-34 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CAK77_RS02315 c8ecc545877404e92b23c1fe5ca685b5 265 SMART SM00525 217 237 5.6E-6 T 06-07-2017 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 CAK77_RS02315 c8ecc545877404e92b23c1fe5ca685b5 265 Gene3D G3DSA:1.10.1670.10 154 237 1.1E-30 T 06-07-2017 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CAK77_RS02315 c8ecc545877404e92b23c1fe5ca685b5 265 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 218 234 - T 06-07-2017 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CAK77_RS02315 c8ecc545877404e92b23c1fe5ca685b5 265 TIGRFAM TIGR01083 nth: endonuclease III 36 225 1.6E-78 T 06-07-2017 IPR005759 Endonuclease III GO:0003906|GO:0006284 CAK77_RS02315 c8ecc545877404e92b23c1fe5ca685b5 265 Hamap MF_00942 Endonuclease III [nth]. 33 240 36.221 T 06-07-2017 IPR005759 Endonuclease III GO:0003906|GO:0006284 CAK77_RS02315 c8ecc545877404e92b23c1fe5ca685b5 265 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 65 199 5.6E-22 T 06-07-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CAK77_RS02315 c8ecc545877404e92b23c1fe5ca685b5 265 SUPERFAMILY SSF48150 38 237 4.87E-63 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CAK77_RS02315 c8ecc545877404e92b23c1fe5ca685b5 265 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 218 234 3.1E-5 T 06-07-2017 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 CAK77_RS02315 c8ecc545877404e92b23c1fe5ca685b5 265 ProSitePatterns PS01155 Endonuclease III family signature. 133 162 - T 06-07-2017 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 CAK77_RS02315 c8ecc545877404e92b23c1fe5ca685b5 265 SMART SM00478 69 216 1.1E-56 T 06-07-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CAK77_RS02315 c8ecc545877404e92b23c1fe5ca685b5 265 Pfam PF00633 Helix-hairpin-helix motif 130 157 3.4E-8 T 06-07-2017 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 CAK77_RS17060 47ac95c48c86ade543071a8a6b398f41 492 Pfam PF00067 Cytochrome P450 60 466 3.3E-67 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS17060 47ac95c48c86ade543071a8a6b398f41 492 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 431 440 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CAK77_RS17060 47ac95c48c86ade543071a8a6b398f41 492 PRINTS PR00385 P450 superfamily signature 303 320 1.5E-7 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS17060 47ac95c48c86ade543071a8a6b398f41 492 PRINTS PR00385 P450 superfamily signature 438 449 1.5E-7 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS17060 47ac95c48c86ade543071a8a6b398f41 492 PRINTS PR00385 P450 superfamily signature 429 438 1.5E-7 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS17060 47ac95c48c86ade543071a8a6b398f41 492 PRINTS PR00385 P450 superfamily signature 353 364 1.5E-7 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS17060 47ac95c48c86ade543071a8a6b398f41 492 PRINTS PR00385 P450 superfamily signature 320 333 1.5E-7 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS17060 47ac95c48c86ade543071a8a6b398f41 492 Gene3D G3DSA:1.10.630.10 54 490 6.7E-99 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS17060 47ac95c48c86ade543071a8a6b398f41 492 SUPERFAMILY SSF48264 56 490 2.23E-99 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS17060 47ac95c48c86ade543071a8a6b398f41 492 PRINTS PR00465 E-class P450 group IV signature 293 319 5.7E-23 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS17060 47ac95c48c86ade543071a8a6b398f41 492 PRINTS PR00465 E-class P450 group IV signature 438 456 5.7E-23 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS17060 47ac95c48c86ade543071a8a6b398f41 492 PRINTS PR00465 E-class P450 group IV signature 348 364 5.7E-23 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS17060 47ac95c48c86ade543071a8a6b398f41 492 PRINTS PR00465 E-class P450 group IV signature 55 72 5.7E-23 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS17060 47ac95c48c86ade543071a8a6b398f41 492 PRINTS PR00465 E-class P450 group IV signature 422 438 5.7E-23 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS17060 47ac95c48c86ade543071a8a6b398f41 492 PRINTS PR00465 E-class P450 group IV signature 397 415 5.7E-23 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS17060 47ac95c48c86ade543071a8a6b398f41 492 PRINTS PR00465 E-class P450 group IV signature 381 395 5.7E-23 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS05955 0a8bf3677a41e90ed6c8b6e9ef77146b 293 TIGRFAM TIGR01692 HIBADH: 3-hydroxyisobutyrate dehydrogenase 6 287 8.1E-111 T 06-07-2017 IPR011548 3-hydroxyisobutyrate dehydrogenase GO:0008442|GO:0051287|GO:0055114 KEGG: 00280+1.1.1.31|Reactome: R-HSA-70895 CAK77_RS05955 0a8bf3677a41e90ed6c8b6e9ef77146b 293 PIRSF PIRSF000103 1 293 1.2E-79 T 06-07-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CAK77_RS05955 0a8bf3677a41e90ed6c8b6e9ef77146b 293 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 162 286 2.6E-35 T 06-07-2017 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 CAK77_RS05955 0a8bf3677a41e90ed6c8b6e9ef77146b 293 SUPERFAMILY SSF48179 161 290 1.47E-36 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAK77_RS05955 0a8bf3677a41e90ed6c8b6e9ef77146b 293 SUPERFAMILY SSF51735 1 159 3.45E-45 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS05955 0a8bf3677a41e90ed6c8b6e9ef77146b 293 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 6 19 - T 06-07-2017 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 CAK77_RS05955 0a8bf3677a41e90ed6c8b6e9ef77146b 293 Gene3D G3DSA:3.40.50.720 2 160 1.2E-57 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS05955 0a8bf3677a41e90ed6c8b6e9ef77146b 293 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 3 159 4.5E-50 T 06-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CAK77_RS05955 0a8bf3677a41e90ed6c8b6e9ef77146b 293 Gene3D G3DSA:1.10.1040.10 162 289 6.7E-41 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAK77_RS17530 34aa2b306718b4a0d017de46234d2dbc 988 Pfam PF03699 Uncharacterised protein family (UPF0182) 22 826 5.1E-266 T 06-07-2017 IPR005372 Uncharacterised protein family UPF0182 GO:0016021 CAK77_RS17530 34aa2b306718b4a0d017de46234d2dbc 988 Hamap MF_01600 UPF0182 protein . 11 907 17.401 T 06-07-2017 IPR005372 Uncharacterised protein family UPF0182 GO:0016021 CAK77_RS08230 f39a66bb988a0b4e0d5b130e52f2747e 368 PRINTS PR00474 Glutamate 5-kinase family signature 217 237 1.1E-49 T 06-07-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 CAK77_RS08230 f39a66bb988a0b4e0d5b130e52f2747e 368 PRINTS PR00474 Glutamate 5-kinase family signature 158 185 1.1E-49 T 06-07-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 CAK77_RS08230 f39a66bb988a0b4e0d5b130e52f2747e 368 PRINTS PR00474 Glutamate 5-kinase family signature 126 147 1.1E-49 T 06-07-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 CAK77_RS08230 f39a66bb988a0b4e0d5b130e52f2747e 368 PRINTS PR00474 Glutamate 5-kinase family signature 86 114 1.1E-49 T 06-07-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 CAK77_RS08230 f39a66bb988a0b4e0d5b130e52f2747e 368 PRINTS PR00474 Glutamate 5-kinase family signature 52 66 1.1E-49 T 06-07-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 CAK77_RS08230 f39a66bb988a0b4e0d5b130e52f2747e 368 Gene3D G3DSA:2.30.130.10 280 367 8.9E-22 T 06-07-2017 IPR015947 PUA-like domain CAK77_RS08230 f39a66bb988a0b4e0d5b130e52f2747e 368 Gene3D G3DSA:3.40.1160.10 15 260 2.4E-55 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase CAK77_RS08230 f39a66bb988a0b4e0d5b130e52f2747e 368 Hamap MF_00456 Glutamate 5-kinase [proB]. 15 263 32.804 T 06-07-2017 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CAK77_RS08230 f39a66bb988a0b4e0d5b130e52f2747e 368 PIRSF PIRSF000729 10 368 2.6E-117 T 06-07-2017 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 CAK77_RS08230 f39a66bb988a0b4e0d5b130e52f2747e 368 SUPERFAMILY SSF53633 15 260 4.84E-58 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase CAK77_RS08230 f39a66bb988a0b4e0d5b130e52f2747e 368 SMART SM00359 282 361 5.3E-17 T 06-07-2017 IPR002478 PUA domain GO:0003723 CAK77_RS08230 f39a66bb988a0b4e0d5b130e52f2747e 368 TIGRFAM TIGR01027 proB: glutamate 5-kinase 15 367 4.3E-129 T 06-07-2017 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CAK77_RS08230 f39a66bb988a0b4e0d5b130e52f2747e 368 Pfam PF01472 PUA domain 282 352 1.3E-16 T 06-07-2017 IPR002478 PUA domain GO:0003723 CAK77_RS08230 f39a66bb988a0b4e0d5b130e52f2747e 368 SUPERFAMILY SSF88697 282 367 2.54E-16 T 06-07-2017 IPR015947 PUA-like domain CAK77_RS08230 f39a66bb988a0b4e0d5b130e52f2747e 368 Pfam PF00696 Amino acid kinase family 16 242 6.1E-34 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase CAK77_RS08230 f39a66bb988a0b4e0d5b130e52f2747e 368 ProSitePatterns PS00902 Glutamate 5-kinase signature. 215 232 - T 06-07-2017 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CAK77_RS01815 0448842cbfa7be7d6fbdbc3cda839ca7 220 Pfam PF14032 PknH-like extracellular domain 28 211 3.0E-33 T 06-07-2017 IPR026954 PknH-like extracellular domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 CAK77_RS18520 225d365f0d77abda6f83c1debbd56f5d 378 TIGRFAM TIGR01304 IMP_DH_rel_2: IMP dehydrogenase family protein 5 376 1.1E-181 T 06-07-2017 IPR005992 IMP dehydrogenase-related 2 GO:0016491|GO:0055114 CAK77_RS18520 225d365f0d77abda6f83c1debbd56f5d 378 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 19 305 1.7E-32 T 06-07-2017 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 CAK77_RS18520 225d365f0d77abda6f83c1debbd56f5d 378 SUPERFAMILY SSF51412 9 78 4.06E-57 T 06-07-2017 CAK77_RS18520 225d365f0d77abda6f83c1debbd56f5d 378 SUPERFAMILY SSF51412 119 374 4.06E-57 T 06-07-2017 CAK77_RS18520 225d365f0d77abda6f83c1debbd56f5d 378 Gene3D G3DSA:3.20.20.70 17 374 5.2E-68 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK77_RS18520 225d365f0d77abda6f83c1debbd56f5d 378 SMART SM01240 18 377 1.8E-13 T 06-07-2017 CAK77_RS00595 839ff1581e7e857eaaeb2c5fbb7377de 379 SUPERFAMILY SSF52343 160 287 7.73E-26 T 06-07-2017 CAK77_RS00595 839ff1581e7e857eaaeb2c5fbb7377de 379 Pfam PF00970 Oxidoreductase FAD-binding domain 80 164 1.4E-4 T 06-07-2017 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 CAK77_RS00595 839ff1581e7e857eaaeb2c5fbb7377de 379 Gene3D G3DSA:3.40.50.80 172 278 9.1E-23 T 06-07-2017 CAK77_RS00595 839ff1581e7e857eaaeb2c5fbb7377de 379 PRINTS PR00409 Phthalate dioxygenase reductase family signature 114 128 4.6E-21 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 CAK77_RS00595 839ff1581e7e857eaaeb2c5fbb7377de 379 PRINTS PR00409 Phthalate dioxygenase reductase family signature 138 152 4.6E-21 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 CAK77_RS00595 839ff1581e7e857eaaeb2c5fbb7377de 379 PRINTS PR00409 Phthalate dioxygenase reductase family signature 102 114 4.6E-21 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 CAK77_RS00595 839ff1581e7e857eaaeb2c5fbb7377de 379 PRINTS PR00409 Phthalate dioxygenase reductase family signature 152 166 4.6E-21 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 CAK77_RS00595 839ff1581e7e857eaaeb2c5fbb7377de 379 PRINTS PR00409 Phthalate dioxygenase reductase family signature 92 102 4.6E-21 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 CAK77_RS00595 839ff1581e7e857eaaeb2c5fbb7377de 379 PRINTS PR00409 Phthalate dioxygenase reductase family signature 252 260 4.6E-21 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 CAK77_RS00595 839ff1581e7e857eaaeb2c5fbb7377de 379 Gene3D G3DSA:2.40.30.10 63 162 1.4E-29 T 06-07-2017 CAK77_RS00595 839ff1581e7e857eaaeb2c5fbb7377de 379 SUPERFAMILY SSF54292 274 377 5.9E-22 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK77_RS00595 839ff1581e7e857eaaeb2c5fbb7377de 379 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 304 366 2.0E-10 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK77_RS00595 839ff1581e7e857eaaeb2c5fbb7377de 379 Gene3D G3DSA:3.10.20.30 279 377 7.5E-24 T 06-07-2017 IPR012675 Beta-grasp domain CAK77_RS00595 839ff1581e7e857eaaeb2c5fbb7377de 379 SUPERFAMILY SSF63380 64 162 2.6E-25 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CAK77_RS00595 839ff1581e7e857eaaeb2c5fbb7377de 379 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 327 335 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CAK77_RS03550 c19f08857c383e7bff5a80f27050fef6 390 SUPERFAMILY SSF53383 5 388 5.92E-97 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK77_RS03550 c19f08857c383e7bff5a80f27050fef6 390 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 233 246 - T 06-07-2017 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CAK77_RS03550 c19f08857c383e7bff5a80f27050fef6 390 Pfam PF00155 Aminotransferase class I and II 31 380 1.4E-61 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAK77_RS03550 c19f08857c383e7bff5a80f27050fef6 390 Gene3D G3DSA:3.90.1150.10 256 387 4.3E-32 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK77_RS03550 c19f08857c383e7bff5a80f27050fef6 390 Gene3D G3DSA:3.40.640.10 45 255 4.3E-62 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK77_RS12645 8e43328197ec1adf30c33a5a8e41bde9 373 Gene3D G3DSA:1.10.150.130 34 114 6.9E-4 T 06-07-2017 IPR023109 Integrase/recombinase, N-terminal CAK77_RS12645 8e43328197ec1adf30c33a5a8e41bde9 373 Pfam PF00589 Phage integrase family 174 350 1.7E-19 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAK77_RS12645 8e43328197ec1adf30c33a5a8e41bde9 373 Gene3D G3DSA:1.10.443.10 152 358 9.3E-36 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAK77_RS12645 8e43328197ec1adf30c33a5a8e41bde9 373 SUPERFAMILY SSF56349 151 358 7.95E-34 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CAK77_RS12645 8e43328197ec1adf30c33a5a8e41bde9 373 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 33 114 2.3E-6 T 06-07-2017 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CAK77_RS20420 cd6f3213427a3d349b04924cddff745e 262 Pfam PF00795 Carbon-nitrogen hydrolase 5 251 6.5E-38 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAK77_RS20420 cd6f3213427a3d349b04924cddff745e 262 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 138 158 - T 06-07-2017 IPR001110 Uncharacterised protein family UPF0012, conserved site CAK77_RS20420 cd6f3213427a3d349b04924cddff745e 262 SUPERFAMILY SSF56317 1 257 1.83E-60 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAK77_RS20420 cd6f3213427a3d349b04924cddff745e 262 Gene3D G3DSA:3.60.110.10 1 256 1.4E-63 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAK77_RS23795 dcbea75c709cbe4ad2321ba5bc5dc09a 168 Pfam PF00440 Bacterial regulatory proteins, tetR family 1 40 2.3E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS23795 dcbea75c709cbe4ad2321ba5bc5dc09a 168 Gene3D G3DSA:1.10.357.10 42 163 1.2E-30 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS23795 dcbea75c709cbe4ad2321ba5bc5dc09a 168 SUPERFAMILY SSF48498 59 163 5.11E-27 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS23795 dcbea75c709cbe4ad2321ba5bc5dc09a 168 Gene3D G3DSA:1.10.10.60 1 41 1.1E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS23795 dcbea75c709cbe4ad2321ba5bc5dc09a 168 SUPERFAMILY SSF46689 1 45 1.54E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS04395 88d2d57ad1706eedbcf3a4c9fc5e2c82 235 SUPERFAMILY SSF53335 9 191 2.74E-34 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS04395 88d2d57ad1706eedbcf3a4c9fc5e2c82 235 Gene3D G3DSA:3.40.50.150 25 185 1.9E-30 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS04395 88d2d57ad1706eedbcf3a4c9fc5e2c82 235 Pfam PF13649 Methyltransferase domain 48 141 1.5E-19 T 06-07-2017 CAK77_RS02870 b6f4bafd0909a0321d6b2dcfa059b9a2 446 Gene3D G3DSA:3.40.710.10 149 294 4.3E-31 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK77_RS02870 b6f4bafd0909a0321d6b2dcfa059b9a2 446 Gene3D G3DSA:3.40.710.10 341 422 4.3E-31 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK77_RS02870 b6f4bafd0909a0321d6b2dcfa059b9a2 446 SUPERFAMILY SSF56601 337 423 5.92E-32 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK77_RS02870 b6f4bafd0909a0321d6b2dcfa059b9a2 446 SUPERFAMILY SSF56601 47 283 5.92E-32 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK77_RS02870 b6f4bafd0909a0321d6b2dcfa059b9a2 446 Pfam PF13354 Beta-lactamase enzyme family 176 323 3.9E-24 T 06-07-2017 CAK77_RS11940 c34b7639fea37903024d257aa42b4a09 195 SUPERFAMILY SSF48498 92 194 2.72E-10 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS11940 c34b7639fea37903024d257aa42b4a09 195 Gene3D G3DSA:1.10.357.10 23 193 6.2E-29 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS11940 c34b7639fea37903024d257aa42b4a09 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 70 9.7E-14 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS11940 c34b7639fea37903024d257aa42b4a09 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 3.2E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS11940 c34b7639fea37903024d257aa42b4a09 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 38 3.2E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS11940 c34b7639fea37903024d257aa42b4a09 195 SUPERFAMILY SSF46689 23 94 6.16E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS09795 2d37ee9268b68e0c8b9cb92a8a762453 114 SUPERFAMILY SSF46785 6 99 6.2E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS09795 2d37ee9268b68e0c8b9cb92a8a762453 114 Gene3D G3DSA:1.10.10.10 7 105 3.7E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS09795 2d37ee9268b68e0c8b9cb92a8a762453 114 Pfam PF12840 Helix-turn-helix domain 10 67 6.1E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS09795 2d37ee9268b68e0c8b9cb92a8a762453 114 SMART SM00418 8 87 9.4E-12 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK77_RS09795 2d37ee9268b68e0c8b9cb92a8a762453 114 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 10 25 7.3E-5 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK77_RS09795 2d37ee9268b68e0c8b9cb92a8a762453 114 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 43 58 7.3E-5 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK77_RS09795 2d37ee9268b68e0c8b9cb92a8a762453 114 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 58 73 7.3E-5 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK77_RS00495 9d94c8555b0bfd49020d7d350beb47dd 212 SMART SM00345 13 71 6.3E-13 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK77_RS00495 9d94c8555b0bfd49020d7d350beb47dd 212 Gene3D G3DSA:1.20.120.530 75 207 5.8E-26 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAK77_RS00495 9d94c8555b0bfd49020d7d350beb47dd 212 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 71 1.4E-14 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK77_RS00495 9d94c8555b0bfd49020d7d350beb47dd 212 SMART SM00895 81 207 5.6E-15 T 06-07-2017 IPR011711 GntR, C-terminal CAK77_RS00495 9d94c8555b0bfd49020d7d350beb47dd 212 SUPERFAMILY SSF46785 8 96 1.63E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS00495 9d94c8555b0bfd49020d7d350beb47dd 212 SUPERFAMILY SSF48008 76 208 4.45E-25 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAK77_RS00495 9d94c8555b0bfd49020d7d350beb47dd 212 Gene3D G3DSA:1.10.10.10 8 71 9.5E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS00495 9d94c8555b0bfd49020d7d350beb47dd 212 Pfam PF07729 FCD domain 83 205 3.9E-23 T 06-07-2017 IPR011711 GntR, C-terminal CAK77_RS00495 9d94c8555b0bfd49020d7d350beb47dd 212 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 31 45 1.5E-5 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK77_RS00495 9d94c8555b0bfd49020d7d350beb47dd 212 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 45 61 1.5E-5 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK77_RS19070 20cdbd3d3047fa7fdaf33fb2a28f2d53 101 SUPERFAMILY SSF54999 5 100 1.07E-36 T 06-07-2017 IPR027486 Ribosomal protein S10 domain CAK77_RS19070 20cdbd3d3047fa7fdaf33fb2a28f2d53 101 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 06-07-2017 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK77_RS19070 20cdbd3d3047fa7fdaf33fb2a28f2d53 101 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 101 24.494 T 06-07-2017 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK77_RS19070 20cdbd3d3047fa7fdaf33fb2a28f2d53 101 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 3.7E-21 T 06-07-2017 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK77_RS19070 20cdbd3d3047fa7fdaf33fb2a28f2d53 101 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 3.7E-21 T 06-07-2017 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK77_RS19070 20cdbd3d3047fa7fdaf33fb2a28f2d53 101 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 3.7E-21 T 06-07-2017 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK77_RS19070 20cdbd3d3047fa7fdaf33fb2a28f2d53 101 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 4.4E-46 T 06-07-2017 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK77_RS19070 20cdbd3d3047fa7fdaf33fb2a28f2d53 101 SMART SM01403 7 101 3.0E-55 T 06-07-2017 IPR027486 Ribosomal protein S10 domain CAK77_RS19070 20cdbd3d3047fa7fdaf33fb2a28f2d53 101 Gene3D G3DSA:3.30.70.600 4 100 1.3E-42 T 06-07-2017 IPR027486 Ribosomal protein S10 domain CAK77_RS19070 20cdbd3d3047fa7fdaf33fb2a28f2d53 101 Pfam PF00338 Ribosomal protein S10p/S20e 7 100 1.1E-34 T 06-07-2017 IPR027486 Ribosomal protein S10 domain CAK77_RS20615 c49ecff177c93ab68fceed8a95702686 288 SUPERFAMILY SSF53448 3 285 3.47E-80 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK77_RS20615 c49ecff177c93ab68fceed8a95702686 288 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 2 286 7.5E-142 T 06-07-2017 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688 CAK77_RS20615 c49ecff177c93ab68fceed8a95702686 288 Pfam PF00483 Nucleotidyl transferase 3 235 8.6E-62 T 06-07-2017 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CAK77_RS20615 c49ecff177c93ab68fceed8a95702686 288 Gene3D G3DSA:3.90.550.10 3 263 3.6E-61 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK77_RS02255 26ebac7812a6ecb5f32ff8e20f5a72cc 356 SUPERFAMILY SSF53686 22 337 2.49E-65 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAK77_RS02255 26ebac7812a6ecb5f32ff8e20f5a72cc 356 Gene3D G3DSA:3.40.50.1100 51 145 1.6E-22 T 06-07-2017 CAK77_RS02255 26ebac7812a6ecb5f32ff8e20f5a72cc 356 Gene3D G3DSA:3.40.50.1100 146 337 5.0E-38 T 06-07-2017 CAK77_RS02255 26ebac7812a6ecb5f32ff8e20f5a72cc 356 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 35 315 1.6E-43 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAK77_RS03575 d9e6f50190b35d2c3afe1442d7982c31 711 ProSitePatterns PS00708 Prolyl endopeptidase family serine active site. 531 561 - T 06-07-2017 IPR002471 Peptidase S9, serine active site GO:0004252|GO:0006508 CAK77_RS03575 d9e6f50190b35d2c3afe1442d7982c31 711 SUPERFAMILY SSF53474 439 702 3.62E-39 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS03575 d9e6f50190b35d2c3afe1442d7982c31 711 Pfam PF00326 Prolyl oligopeptidase family 485 702 4.6E-62 T 06-07-2017 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 CAK77_RS03575 d9e6f50190b35d2c3afe1442d7982c31 711 SUPERFAMILY SSF50993 5 435 8.89E-89 T 06-07-2017 CAK77_RS03575 d9e6f50190b35d2c3afe1442d7982c31 711 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 631 653 4.8E-55 T 06-07-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CAK77_RS03575 d9e6f50190b35d2c3afe1442d7982c31 711 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 524 543 4.8E-55 T 06-07-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CAK77_RS03575 d9e6f50190b35d2c3afe1442d7982c31 711 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 554 574 4.8E-55 T 06-07-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CAK77_RS03575 d9e6f50190b35d2c3afe1442d7982c31 711 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 470 488 4.8E-55 T 06-07-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CAK77_RS03575 d9e6f50190b35d2c3afe1442d7982c31 711 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 496 520 4.8E-55 T 06-07-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CAK77_RS03575 d9e6f50190b35d2c3afe1442d7982c31 711 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 613 628 4.8E-55 T 06-07-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CAK77_RS03575 d9e6f50190b35d2c3afe1442d7982c31 711 Pfam PF02897 Prolyl oligopeptidase, N-terminal beta-propeller domain 8 429 4.5E-93 T 06-07-2017 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 CAK77_RS03575 d9e6f50190b35d2c3afe1442d7982c31 711 Gene3D G3DSA:2.130.10.120 75 432 1.0E-101 T 06-07-2017 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 CAK77_RS03575 d9e6f50190b35d2c3afe1442d7982c31 711 Gene3D G3DSA:3.40.50.1820 450 701 1.1E-29 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS19405 88bda5c6e3cf31641cd6fc1f9cb49b41 232 SUPERFAMILY SSF54909 124 222 2.04E-20 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAK77_RS19405 88bda5c6e3cf31641cd6fc1f9cb49b41 232 SUPERFAMILY SSF54909 8 109 3.75E-21 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAK77_RS19405 88bda5c6e3cf31641cd6fc1f9cb49b41 232 Pfam PF03795 YCII-related domain 140 218 4.3E-7 T 06-07-2017 IPR005545 YCII-related CAK77_RS19405 88bda5c6e3cf31641cd6fc1f9cb49b41 232 Pfam PF03795 YCII-related domain 14 109 6.3E-11 T 06-07-2017 IPR005545 YCII-related CAK77_RS19405 88bda5c6e3cf31641cd6fc1f9cb49b41 232 Gene3D G3DSA:3.30.70.1060 1 110 9.7E-25 T 06-07-2017 CAK77_RS19405 88bda5c6e3cf31641cd6fc1f9cb49b41 232 Gene3D G3DSA:3.30.70.1060 122 229 8.1E-23 T 06-07-2017 CAK77_RS13170 c71e462bd2e685ce0fd202e52d040f89 225 Gene3D G3DSA:3.40.50.300 1 199 7.5E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS13170 c71e462bd2e685ce0fd202e52d040f89 225 PIRSF PIRSF006755 1 202 3.0E-36 T 06-07-2017 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 CAK77_RS13170 c71e462bd2e685ce0fd202e52d040f89 225 Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. 1 207 23.914 T 06-07-2017 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 CAK77_RS13170 c71e462bd2e685ce0fd202e52d040f89 225 Pfam PF13500 AAA domain 4 197 1.1E-31 T 06-07-2017 CAK77_RS13170 c71e462bd2e685ce0fd202e52d040f89 225 TIGRFAM TIGR00347 bioD: dethiobiotin synthase 5 165 2.6E-28 T 06-07-2017 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 CAK77_RS13170 c71e462bd2e685ce0fd202e52d040f89 225 SUPERFAMILY SSF52540 1 201 6.04E-39 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS01330 9020cb2d80a9ca6bca81f957916bfa1e 260 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 256 5.2E-48 T 06-07-2017 CAK77_RS01330 9020cb2d80a9ca6bca81f957916bfa1e 260 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 192 0.0038 T 06-07-2017 CAK77_RS01330 9020cb2d80a9ca6bca81f957916bfa1e 260 SUPERFAMILY SSF51735 7 257 4.65E-69 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS01330 9020cb2d80a9ca6bca81f957916bfa1e 260 Gene3D G3DSA:3.40.50.720 2 256 6.4E-67 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS01330 9020cb2d80a9ca6bca81f957916bfa1e 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 2.8E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS01330 9020cb2d80a9ca6bca81f957916bfa1e 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 2.8E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS01330 9020cb2d80a9ca6bca81f957916bfa1e 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 2.8E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS01330 9020cb2d80a9ca6bca81f957916bfa1e 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 2.8E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS01330 9020cb2d80a9ca6bca81f957916bfa1e 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 2.8E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS01330 9020cb2d80a9ca6bca81f957916bfa1e 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 221 241 2.8E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS11015 cc2b8fd637606a45b2b90ef3441ab626 426 Gene3D G3DSA:3.90.1150.10 329 423 3.2E-30 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK77_RS11015 cc2b8fd637606a45b2b90ef3441ab626 426 Gene3D G3DSA:3.90.1150.10 19 66 3.2E-30 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK77_RS11015 cc2b8fd637606a45b2b90ef3441ab626 426 TIGRFAM TIGR02407 ectoine_ectB: diaminobutyrate--2-oxoglutarate aminotransferase 15 422 1.3E-197 T 06-07-2017 IPR012773 Ectoine biosynthetic protein GO:0019491|GO:0030170|GO:0047307 KEGG: 00260+2.6.1.76|MetaCyc: PWY-6409|MetaCyc: PWY-6562|MetaCyc: PWY-761 CAK77_RS11015 cc2b8fd637606a45b2b90ef3441ab626 426 TIGRFAM TIGR00709 dat: 2,4-diaminobutyrate 4-transaminase 16 424 2.9E-142 T 06-07-2017 IPR004637 2,4-diaminobutyrate 4-transaminase GO:0008483|GO:0009058 KEGG: 00260+2.6.1.76|MetaCyc: PWY-6409|MetaCyc: PWY-6562|MetaCyc: PWY-761 CAK77_RS11015 cc2b8fd637606a45b2b90ef3441ab626 426 Gene3D G3DSA:3.40.640.10 67 323 3.0E-63 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK77_RS11015 cc2b8fd637606a45b2b90ef3441ab626 426 Pfam PF00202 Aminotransferase class-III 34 421 1.2E-79 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAK77_RS11015 cc2b8fd637606a45b2b90ef3441ab626 426 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 244 280 - T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAK77_RS11015 cc2b8fd637606a45b2b90ef3441ab626 426 SUPERFAMILY SSF53383 20 422 3.66E-108 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK77_RS08500 88bffbeccb0e1dad07388aacfee05770 350 SUPERFAMILY SSF54791 18 78 3.95E-5 T 06-07-2017 IPR004088 K Homology domain, type 1 GO:0003723 CAK77_RS08500 88bffbeccb0e1dad07388aacfee05770 350 SMART SM00322 16 79 3.1E-5 T 06-07-2017 IPR004087 K Homology domain GO:0003676 CAK77_RS08500 88bffbeccb0e1dad07388aacfee05770 350 Gene3D G3DSA:3.40.50.300 121 326 3.6E-99 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS08500 88bffbeccb0e1dad07388aacfee05770 350 Pfam PF02562 PhoH-like protein 123 325 2.8E-94 T 06-07-2017 IPR003714 PhoH-like protein GO:0005524 CAK77_RS08500 88bffbeccb0e1dad07388aacfee05770 350 SUPERFAMILY SSF52540 122 298 9.9E-40 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS00140 cb62e214bc8f742d830676f961daa67a 743 Gene3D G3DSA:1.10.443.10 351 581 2.3E-20 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAK77_RS00140 cb62e214bc8f742d830676f961daa67a 743 SUPERFAMILY SSF56349 305 569 1.04E-19 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CAK77_RS00140 cb62e214bc8f742d830676f961daa67a 743 Pfam PF00589 Phage integrase family 405 569 3.0E-13 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAK77_RS02450 cb62e214bc8f742d830676f961daa67a 743 Gene3D G3DSA:1.10.443.10 351 581 2.3E-20 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAK77_RS02450 cb62e214bc8f742d830676f961daa67a 743 SUPERFAMILY SSF56349 305 569 1.04E-19 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CAK77_RS02450 cb62e214bc8f742d830676f961daa67a 743 Pfam PF00589 Phage integrase family 405 569 3.0E-13 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAK77_RS16130 816f1370cadfa66bde6b01c3acb56eb8 339 Pfam PF01070 FMN-dependent dehydrogenase 171 332 1.5E-17 T 06-07-2017 IPR000262 FMN-dependent dehydrogenase GO:0016491 CAK77_RS16130 816f1370cadfa66bde6b01c3acb56eb8 339 Pfam PF01070 FMN-dependent dehydrogenase 4 97 9.8E-8 T 06-07-2017 IPR000262 FMN-dependent dehydrogenase GO:0016491 CAK77_RS16130 816f1370cadfa66bde6b01c3acb56eb8 339 SUPERFAMILY SSF51395 24 333 5.04E-69 T 06-07-2017 CAK77_RS16130 816f1370cadfa66bde6b01c3acb56eb8 339 Gene3D G3DSA:3.20.20.70 24 331 6.4E-107 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK77_RS16130 816f1370cadfa66bde6b01c3acb56eb8 339 TIGRFAM TIGR02151 IPP_isom_2: isopentenyl-diphosphate delta-isomerase, type 2 4 330 3.7E-110 T 06-07-2017 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 CAK77_RS16130 816f1370cadfa66bde6b01c3acb56eb8 339 Hamap MF_00354 Isopentenyl-diphosphate delta-isomerase [fni]. 2 334 36.04 T 06-07-2017 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 CAK77_RS16130 816f1370cadfa66bde6b01c3acb56eb8 339 PIRSF PIRSF003314 1 337 1.3E-116 T 06-07-2017 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 CAK77_RS02245 a759db584ad0a5e5983533f0aa3ea78a 392 Gene3D G3DSA:1.10.150.130 84 178 2.3E-10 T 06-07-2017 IPR023109 Integrase/recombinase, N-terminal CAK77_RS02245 a759db584ad0a5e5983533f0aa3ea78a 392 Gene3D G3DSA:1.10.443.10 185 378 8.4E-38 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAK77_RS02245 a759db584ad0a5e5983533f0aa3ea78a 392 Pfam PF00589 Phage integrase family 187 364 7.8E-25 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAK77_RS02245 a759db584ad0a5e5983533f0aa3ea78a 392 SUPERFAMILY SSF56349 84 369 3.53E-54 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CAK77_RS14445 22324b31a013fceea76c1a194beeff67 866 Gene3D G3DSA:3.40.50.1000 480 523 1.9E-54 T 06-07-2017 IPR023214 HAD-like domain CAK77_RS14445 22324b31a013fceea76c1a194beeff67 866 Gene3D G3DSA:3.40.50.1000 636 776 1.9E-54 T 06-07-2017 IPR023214 HAD-like domain CAK77_RS14445 22324b31a013fceea76c1a194beeff67 866 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 708 727 5.3E-29 T 06-07-2017 CAK77_RS14445 22324b31a013fceea76c1a194beeff67 866 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 655 665 5.3E-29 T 06-07-2017 CAK77_RS14445 22324b31a013fceea76c1a194beeff67 866 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 357 371 5.3E-29 T 06-07-2017 CAK77_RS14445 22324b31a013fceea76c1a194beeff67 866 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 633 644 5.3E-29 T 06-07-2017 CAK77_RS14445 22324b31a013fceea76c1a194beeff67 866 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 509 523 5.3E-29 T 06-07-2017 CAK77_RS14445 22324b31a013fceea76c1a194beeff67 866 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 731 743 5.3E-29 T 06-07-2017 CAK77_RS14445 22324b31a013fceea76c1a194beeff67 866 Gene3D G3DSA:2.70.150.10 270 408 1.5E-35 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 CAK77_RS14445 22324b31a013fceea76c1a194beeff67 866 Pfam PF00702 haloacid dehalogenase-like hydrolase 506 722 2.9E-41 T 06-07-2017 CAK77_RS14445 22324b31a013fceea76c1a194beeff67 866 SUPERFAMILY SSF56784 507 527 4.51E-55 T 06-07-2017 IPR023214 HAD-like domain CAK77_RS14445 22324b31a013fceea76c1a194beeff67 866 SUPERFAMILY SSF56784 566 814 4.51E-55 T 06-07-2017 IPR023214 HAD-like domain CAK77_RS14445 22324b31a013fceea76c1a194beeff67 866 SUPERFAMILY SSF81653 311 407 9.02E-31 T 06-07-2017 CAK77_RS14445 22324b31a013fceea76c1a194beeff67 866 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 279 787 2.8E-91 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CAK77_RS14445 22324b31a013fceea76c1a194beeff67 866 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 240 817 2.7E-187 T 06-07-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CAK77_RS14445 22324b31a013fceea76c1a194beeff67 866 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 511 517 - T 06-07-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CAK77_RS14445 22324b31a013fceea76c1a194beeff67 866 SUPERFAMILY SSF81665 275 311 2.75E-15 T 06-07-2017 CAK77_RS14445 22324b31a013fceea76c1a194beeff67 866 SUPERFAMILY SSF81665 408 503 2.75E-15 T 06-07-2017 CAK77_RS14445 22324b31a013fceea76c1a194beeff67 866 SUPERFAMILY SSF81665 757 792 2.75E-15 T 06-07-2017 CAK77_RS14445 22324b31a013fceea76c1a194beeff67 866 Pfam PF13473 Cupredoxin-like domain 16 122 6.2E-16 T 06-07-2017 IPR028096 EfeO-type cupredoxin-like domain CAK77_RS14445 22324b31a013fceea76c1a194beeff67 866 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 221 818 5.9E-183 T 06-07-2017 CAK77_RS14445 22324b31a013fceea76c1a194beeff67 866 Gene3D G3DSA:3.40.1110.10 524 635 2.4E-21 T 06-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CAK77_RS14445 22324b31a013fceea76c1a194beeff67 866 Gene3D G3DSA:2.60.40.420 34 122 2.0E-8 T 06-07-2017 IPR008972 Cupredoxin CAK77_RS14445 22324b31a013fceea76c1a194beeff67 866 SUPERFAMILY SSF49503 20 122 1.17E-11 T 06-07-2017 IPR008972 Cupredoxin CAK77_RS14445 22324b31a013fceea76c1a194beeff67 866 Pfam PF00122 E1-E2 ATPase 279 500 4.3E-69 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 CAK77_RS14445 22324b31a013fceea76c1a194beeff67 866 PRINTS PR00943 Copper-transporting ATPase signature 685 702 3.4E-11 T 06-07-2017 CAK77_RS14445 22324b31a013fceea76c1a194beeff67 866 PRINTS PR00943 Copper-transporting ATPase signature 430 444 3.4E-11 T 06-07-2017 CAK77_RS14445 22324b31a013fceea76c1a194beeff67 866 PRINTS PR00943 Copper-transporting ATPase signature 277 296 3.4E-11 T 06-07-2017 CAK77_RS14445 22324b31a013fceea76c1a194beeff67 866 PRINTS PR00943 Copper-transporting ATPase signature 225 244 3.4E-11 T 06-07-2017 CAK77_RS14445 22324b31a013fceea76c1a194beeff67 866 PRINTS PR00943 Copper-transporting ATPase signature 492 507 3.4E-11 T 06-07-2017 CAK77_RS08275 906fbd115b87c0900a9a0db1cf33844c 137 SUPERFAMILY SSF81301 7 117 4.41E-38 T 06-07-2017 CAK77_RS08275 906fbd115b87c0900a9a0db1cf33844c 137 Pfam PF02410 Ribosomal silencing factor during starvation 15 108 7.8E-25 T 06-07-2017 CAK77_RS08275 906fbd115b87c0900a9a0db1cf33844c 137 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 12 108 8.7E-32 T 06-07-2017 IPR004394 Protein Iojap/ribosomal silencing factor RsfS CAK77_RS08275 906fbd115b87c0900a9a0db1cf33844c 137 Gene3D G3DSA:3.30.460.10 7 112 1.5E-35 T 06-07-2017 CAK77_RS08275 906fbd115b87c0900a9a0db1cf33844c 137 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 7 109 22.841 T 06-07-2017 IPR004394 Protein Iojap/ribosomal silencing factor RsfS CAK77_RS02545 29865a2eb222ba1ae0998cd9659fa530 769 Gene3D G3DSA:3.40.50.300 49 231 9.5E-29 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS02545 29865a2eb222ba1ae0998cd9659fa530 769 SMART SM00487 56 262 5.8E-25 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain CAK77_RS02545 29865a2eb222ba1ae0998cd9659fa530 769 Gene3D G3DSA:3.40.50.300 290 446 1.3E-18 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS02545 29865a2eb222ba1ae0998cd9659fa530 769 SMART SM00490 321 402 9.6E-9 T 06-07-2017 IPR001650 Helicase, C-terminal CAK77_RS02545 29865a2eb222ba1ae0998cd9659fa530 769 TIGRFAM TIGR03817 DECH_helic: helicase/secretion neighborhood putative DEAH-box helicase 24 765 0.0 T 06-07-2017 IPR022307 DEAD/DEAH-box helicase, putative, actinobacteria CAK77_RS02545 29865a2eb222ba1ae0998cd9659fa530 769 Pfam PF00270 DEAD/DEAH box helicase 63 233 1.8E-21 T 06-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CAK77_RS02545 29865a2eb222ba1ae0998cd9659fa530 769 Pfam PF09369 Domain of unknown function (DUF1998) 660 739 1.5E-18 T 06-07-2017 IPR018973 DEAD/DEAH-box helicase, putative CAK77_RS02545 29865a2eb222ba1ae0998cd9659fa530 769 Pfam PF00271 Helicase conserved C-terminal domain 292 402 9.3E-9 T 06-07-2017 IPR001650 Helicase, C-terminal CAK77_RS02545 29865a2eb222ba1ae0998cd9659fa530 769 SUPERFAMILY SSF52540 270 412 1.01E-38 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS02545 29865a2eb222ba1ae0998cd9659fa530 769 SUPERFAMILY SSF52540 72 235 1.01E-38 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS16910 e6bb102c172f8d11972e053390138986 346 SMART SM00829 12 341 1.5E-5 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAK77_RS16910 e6bb102c172f8d11972e053390138986 346 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 06-07-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CAK77_RS16910 e6bb102c172f8d11972e053390138986 346 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 143 3.8E-28 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAK77_RS16910 e6bb102c172f8d11972e053390138986 346 Gene3D G3DSA:3.40.50.720 181 291 8.9E-18 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS16910 e6bb102c172f8d11972e053390138986 346 Pfam PF00107 Zinc-binding dehydrogenase 185 307 1.7E-18 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAK77_RS16910 e6bb102c172f8d11972e053390138986 346 SUPERFAMILY SSF50129 6 171 1.37E-54 T 06-07-2017 IPR011032 GroES-like CAK77_RS16910 e6bb102c172f8d11972e053390138986 346 Gene3D G3DSA:3.90.180.10 3 180 5.4E-68 T 06-07-2017 IPR011032 GroES-like CAK77_RS16910 e6bb102c172f8d11972e053390138986 346 SUPERFAMILY SSF51735 148 311 2.07E-41 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS00690 11c830e07112577e19b5a71ec0a744ad 428 Gene3D G3DSA:3.30.43.10 3 70 7.7E-16 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CAK77_RS00690 11c830e07112577e19b5a71ec0a744ad 428 Pfam PF04030 D-arabinono-1,4-lactone oxidase 169 421 6.0E-67 T 06-07-2017 IPR007173 D-arabinono-1,4-lactone oxidase GO:0003885|GO:0016020|GO:0055114 CAK77_RS00690 11c830e07112577e19b5a71ec0a744ad 428 Gene3D G3DSA:3.30.465.10 71 174 1.3E-30 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAK77_RS00690 11c830e07112577e19b5a71ec0a744ad 428 SUPERFAMILY SSF56176 4 174 4.21E-45 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAK77_RS00690 11c830e07112577e19b5a71ec0a744ad 428 Pfam PF01565 FAD binding domain 15 146 4.7E-28 T 06-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CAK77_RS00690 11c830e07112577e19b5a71ec0a744ad 428 PIRSF PIRSF000136 1 427 1.1E-108 T 06-07-2017 IPR010031 L-gulonolactone/D-arabinono-1,4-lactone oxidase GO:0016899|GO:0055114 CAK77_RS00690 11c830e07112577e19b5a71ec0a744ad 428 TIGRFAM TIGR01679 bact_FAD_ox: FAD-linked oxidoreductase 4 424 1.1E-121 T 06-07-2017 CAK77_RS12080 9afe1bc0c24b7dc26a60791292d3ae80 580 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 506 522 2.7E-29 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK77_RS12080 9afe1bc0c24b7dc26a60791292d3ae80 580 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 529 537 2.7E-29 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK77_RS12080 9afe1bc0c24b7dc26a60791292d3ae80 580 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 437 456 2.7E-29 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK77_RS12080 9afe1bc0c24b7dc26a60791292d3ae80 580 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 256 266 2.7E-29 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK77_RS12080 9afe1bc0c24b7dc26a60791292d3ae80 580 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 370 377 2.7E-29 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK77_RS12080 9afe1bc0c24b7dc26a60791292d3ae80 580 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 475 486 2.7E-29 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK77_RS12080 9afe1bc0c24b7dc26a60791292d3ae80 580 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 462 471 2.7E-29 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK77_RS12080 9afe1bc0c24b7dc26a60791292d3ae80 580 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 403 412 2.7E-29 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK77_RS12080 9afe1bc0c24b7dc26a60791292d3ae80 580 SUPERFAMILY SSF63380 215 427 6.12E-54 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CAK77_RS12080 9afe1bc0c24b7dc26a60791292d3ae80 580 Gene3D G3DSA:2.40.30.10 216 266 1.0E-38 T 06-07-2017 CAK77_RS12080 9afe1bc0c24b7dc26a60791292d3ae80 580 Gene3D G3DSA:2.40.30.10 368 436 1.0E-38 T 06-07-2017 CAK77_RS12080 9afe1bc0c24b7dc26a60791292d3ae80 580 SUPERFAMILY SSF52218 50 195 1.36E-46 T 06-07-2017 IPR029039 Flavoprotein-like domain CAK77_RS12080 9afe1bc0c24b7dc26a60791292d3ae80 580 Pfam PF00258 Flavodoxin 55 180 2.6E-29 T 06-07-2017 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 CAK77_RS12080 9afe1bc0c24b7dc26a60791292d3ae80 580 Pfam PF00175 Oxidoreductase NAD-binding domain 438 544 7.2E-17 T 06-07-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CAK77_RS12080 9afe1bc0c24b7dc26a60791292d3ae80 580 Gene3D G3DSA:3.40.50.80 437 580 1.7E-58 T 06-07-2017 CAK77_RS12080 9afe1bc0c24b7dc26a60791292d3ae80 580 PRINTS PR00369 Flavodoxin signature 134 144 8.7E-14 T 06-07-2017 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 CAK77_RS12080 9afe1bc0c24b7dc26a60791292d3ae80 580 PRINTS PR00369 Flavodoxin signature 102 113 8.7E-14 T 06-07-2017 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 CAK77_RS12080 9afe1bc0c24b7dc26a60791292d3ae80 580 PRINTS PR00369 Flavodoxin signature 158 177 8.7E-14 T 06-07-2017 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 CAK77_RS12080 9afe1bc0c24b7dc26a60791292d3ae80 580 PRINTS PR00369 Flavodoxin signature 54 67 8.7E-14 T 06-07-2017 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 CAK77_RS12080 9afe1bc0c24b7dc26a60791292d3ae80 580 Gene3D G3DSA:3.40.50.360 46 195 7.1E-46 T 06-07-2017 IPR029039 Flavoprotein-like domain CAK77_RS12080 9afe1bc0c24b7dc26a60791292d3ae80 580 Gene3D G3DSA:1.20.990.10 267 367 1.6E-14 T 06-07-2017 IPR023173 NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain-3 GO:0016491|GO:0055114 CAK77_RS12080 9afe1bc0c24b7dc26a60791292d3ae80 580 PIRSF PIRSF000207 7 580 2.6E-216 T 06-07-2017 IPR010199 Sulphite reductase [NADPH] flavoprotein, alpha chain GO:0000103|GO:0004783|GO:0010181|GO:0019344|GO:0050660|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAK77_RS12080 9afe1bc0c24b7dc26a60791292d3ae80 580 SUPERFAMILY SSF52343 425 580 1.57E-49 T 06-07-2017 CAK77_RS12080 9afe1bc0c24b7dc26a60791292d3ae80 580 Pfam PF00667 FAD binding domain 219 408 7.2E-26 T 06-07-2017 IPR003097 FAD-binding, type 1 GO:0016491|GO:0055114 CAK77_RS05450 66acb79709042f383d5f9c207a000030 108 Pfam PF09723 Zinc ribbon domain 1 40 5.9E-14 T 06-07-2017 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain CAK77_RS05450 66acb79709042f383d5f9c207a000030 108 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 1 51 1.3E-18 T 06-07-2017 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain CAK77_RS05450 66acb79709042f383d5f9c207a000030 108 SMART SM00834 1 41 3.5E-14 T 06-07-2017 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain CAK77_RS12415 10739026f2e925427370212eca6405c7 366 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 7 284 1.4E-42 T 06-07-2017 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CAK77_RS12415 10739026f2e925427370212eca6405c7 366 TIGRFAM TIGR02050 gshA_cyan_rel: carboxylate-amine ligase, YbdK family 6 287 2.0E-75 T 06-07-2017 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CAK77_RS12415 10739026f2e925427370212eca6405c7 366 SUPERFAMILY SSF55931 3 360 3.04E-82 T 06-07-2017 CAK77_RS12415 10739026f2e925427370212eca6405c7 366 Hamap MF_01609 Glutamate--cysteine ligase [gshA]. 1 366 76.256 T 06-07-2017 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CAK77_RS07495 25cf5d88af4d4a2fe435ef454461c2b4 598 Pfam PF00501 AMP-binding enzyme 41 492 1.1E-62 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK77_RS07495 25cf5d88af4d4a2fe435ef454461c2b4 598 SUPERFAMILY SSF56801 21 593 5.1E-86 T 06-07-2017 CAK77_RS07495 25cf5d88af4d4a2fe435ef454461c2b4 598 Gene3D G3DSA:2.30.38.10 392 483 3.9E-18 T 06-07-2017 CAK77_RS07495 25cf5d88af4d4a2fe435ef454461c2b4 598 Gene3D G3DSA:3.30.300.30 484 589 4.8E-11 T 06-07-2017 CAK77_RS07495 25cf5d88af4d4a2fe435ef454461c2b4 598 Gene3D G3DSA:3.40.50.980 195 362 2.4E-18 T 06-07-2017 CAK77_RS07495 25cf5d88af4d4a2fe435ef454461c2b4 598 Gene3D G3DSA:3.40.50.980 25 194 2.2E-24 T 06-07-2017 CAK77_RS07560 57e1b4f488037798f01d01d438b48f09 402 SUPERFAMILY SSF52540 38 281 5.04E-77 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS07560 57e1b4f488037798f01d01d438b48f09 402 ProSitePatterns PS00211 ABC transporters family signature. 172 186 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK77_RS07560 57e1b4f488037798f01d01d438b48f09 402 Pfam PF00005 ABC transporter 57 199 3.3E-34 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK77_RS07560 57e1b4f488037798f01d01d438b48f09 402 SUPERFAMILY SSF50331 277 390 2.95E-8 T 06-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal CAK77_RS07560 57e1b4f488037798f01d01d438b48f09 402 Pfam PF08402 TOBE domain 322 390 4.9E-6 T 06-07-2017 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CAK77_RS07560 57e1b4f488037798f01d01d438b48f09 402 Gene3D G3DSA:3.40.50.300 32 273 2.3E-74 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS07560 57e1b4f488037798f01d01d438b48f09 402 SMART SM00382 66 250 1.2E-18 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS06115 12078fa7c384799ba0e8d98b0d8159f2 492 SUPERFAMILY SSF53720 10 488 3.53E-138 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAK77_RS06115 12078fa7c384799ba0e8d98b0d8159f2 492 TIGRFAM TIGR04284 aldehy_Rv0768: aldehyde dehydrogenase, Rv0768 family 9 490 2.1E-284 T 06-07-2017 IPR026460 Aldehyde dehydrogenase, Rv0768 family CAK77_RS06115 12078fa7c384799ba0e8d98b0d8159f2 492 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 258 265 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CAK77_RS06115 12078fa7c384799ba0e8d98b0d8159f2 492 Pfam PF00171 Aldehyde dehydrogenase family 23 487 1.9E-140 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAK77_RS06115 12078fa7c384799ba0e8d98b0d8159f2 492 Gene3D G3DSA:3.40.605.10 10 267 6.7E-72 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAK77_RS06115 12078fa7c384799ba0e8d98b0d8159f2 492 Gene3D G3DSA:3.40.309.10 268 462 6.4E-55 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAK77_RS12210 ed7667eda948416ee726ac3b46eb12fe 272 Gene3D G3DSA:1.10.10.10 213 271 8.7E-10 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS12210 ed7667eda948416ee726ac3b46eb12fe 272 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 51 271 9.2E-33 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS12210 ed7667eda948416ee726ac3b46eb12fe 272 PRINTS PR00046 Major sigma-70 factor signature 241 256 6.7E-7 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS12210 ed7667eda948416ee726ac3b46eb12fe 272 PRINTS PR00046 Major sigma-70 factor signature 224 236 6.7E-7 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS12210 ed7667eda948416ee726ac3b46eb12fe 272 PRINTS PR00046 Major sigma-70 factor signature 77 90 6.7E-7 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS12210 ed7667eda948416ee726ac3b46eb12fe 272 SUPERFAMILY SSF88946 15 122 2.62E-25 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS12210 ed7667eda948416ee726ac3b46eb12fe 272 SUPERFAMILY SSF88659 190 271 5.98E-16 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS12210 ed7667eda948416ee726ac3b46eb12fe 272 Pfam PF04539 Sigma-70 region 3 136 202 2.0E-11 T 06-07-2017 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS12210 ed7667eda948416ee726ac3b46eb12fe 272 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 47 271 1.4E-88 T 06-07-2017 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS12210 ed7667eda948416ee726ac3b46eb12fe 272 Pfam PF04545 Sigma-70, region 4 220 269 9.6E-16 T 06-07-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS12210 ed7667eda948416ee726ac3b46eb12fe 272 Gene3D G3DSA:1.10.10.10 121 175 4.5E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS12210 ed7667eda948416ee726ac3b46eb12fe 272 Pfam PF04542 Sigma-70 region 2 54 122 1.5E-15 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS12210 ed7667eda948416ee726ac3b46eb12fe 272 Gene3D G3DSA:1.10.601.10 38 120 6.7E-15 T 06-07-2017 CAK77_RS12210 ed7667eda948416ee726ac3b46eb12fe 272 SUPERFAMILY SSF88659 126 202 2.01E-16 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS20965 c9315129707a1ad2fb652e4a9c235daa 378 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 15 292 1.5E-81 T 06-07-2017 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CAK77_RS20965 c9315129707a1ad2fb652e4a9c235daa 378 Hamap MF_01609 Glutamate--cysteine ligase [gshA]. 1 378 103.237 T 06-07-2017 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CAK77_RS20965 c9315129707a1ad2fb652e4a9c235daa 378 TIGRFAM TIGR02050 gshA_cyan_rel: carboxylate-amine ligase, YbdK family 14 297 3.6E-113 T 06-07-2017 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CAK77_RS20965 c9315129707a1ad2fb652e4a9c235daa 378 SUPERFAMILY SSF55931 6 369 1.37E-113 T 06-07-2017 CAK77_RS21390 1a92832e784b2ed072e828b73ee02166 142 Gene3D G3DSA:3.10.129.10 2 136 3.3E-38 T 06-07-2017 IPR029069 HotDog domain CAK77_RS21390 1a92832e784b2ed072e828b73ee02166 142 PIRSF PIRSF003230 2 139 5.5E-21 T 06-07-2017 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 CAK77_RS21390 1a92832e784b2ed072e828b73ee02166 142 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 11 118 3.4E-24 T 06-07-2017 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 CAK77_RS21390 1a92832e784b2ed072e828b73ee02166 142 Pfam PF03061 Thioesterase superfamily 24 106 6.5E-14 T 06-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 CAK77_RS21390 1a92832e784b2ed072e828b73ee02166 142 SUPERFAMILY SSF54637 2 134 1.46E-34 T 06-07-2017 IPR029069 HotDog domain CAK77_RS15590 e7946364b76069678506e5d01d034604 331 Pfam PF08529 NusA N-terminal domain 7 61 3.0E-7 T 06-07-2017 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 CAK77_RS15590 e7946364b76069678506e5d01d034604 331 Pfam PF08529 NusA N-terminal domain 62 100 1.6E-6 T 06-07-2017 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 CAK77_RS15590 e7946364b76069678506e5d01d034604 331 SMART SM00316 110 182 0.0036 T 06-07-2017 IPR022967 RNA-binding domain, S1 CAK77_RS15590 e7946364b76069678506e5d01d034604 331 SUPERFAMILY SSF50249 109 183 1.89E-16 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS15590 e7946364b76069678506e5d01d034604 331 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 1 331 25.354 T 06-07-2017 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 CAK77_RS15590 e7946364b76069678506e5d01d034604 331 Gene3D G3DSA:3.30.1480.10 4 99 4.5E-27 T 06-07-2017 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 CAK77_RS15590 e7946364b76069678506e5d01d034604 331 SUPERFAMILY SSF69705 2 99 2.22E-26 T 06-07-2017 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 CAK77_RS15590 e7946364b76069678506e5d01d034604 331 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 7 327 5.0E-105 T 06-07-2017 IPR010213 Transcription termination factor NusA GO:0003723 CAK77_RS15590 e7946364b76069678506e5d01d034604 331 Gene3D G3DSA:2.40.50.140 106 182 3.6E-26 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS15590 e7946364b76069678506e5d01d034604 331 SUPERFAMILY SSF54814 263 327 2.35E-17 T 06-07-2017 IPR009019 K homology domain, prokaryotic type GO:0003723 CAK77_RS15590 e7946364b76069678506e5d01d034604 331 SUPERFAMILY SSF54814 184 261 5.56E-27 T 06-07-2017 IPR009019 K homology domain, prokaryotic type GO:0003723 CAK77_RS15590 e7946364b76069678506e5d01d034604 331 Gene3D G3DSA:3.30.300.20 183 261 1.2E-32 T 06-07-2017 IPR015946 K homology domain-like, alpha/beta CAK77_RS15590 e7946364b76069678506e5d01d034604 331 Pfam PF13184 NusA-like KH domain 214 281 2.0E-24 T 06-07-2017 IPR025249 KH domain, NusA-like GO:0003723 CAK77_RS15590 e7946364b76069678506e5d01d034604 331 Gene3D G3DSA:3.30.300.20 263 328 7.9E-31 T 06-07-2017 IPR015946 K homology domain-like, alpha/beta CAK77_RS13800 3e69d361c20034080787f1d04bda5e47 102 SMART SM01409 34 98 4.1E-11 T 06-07-2017 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CAK77_RS13800 3e69d361c20034080787f1d04bda5e47 102 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 27 99 13.881 T 06-07-2017 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK77_RS13800 3e69d361c20034080787f1d04bda5e47 102 Pfam PF01192 RNA polymerase Rpb6 34 95 4.3E-13 T 06-07-2017 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CAK77_RS13800 3e69d361c20034080787f1d04bda5e47 102 Gene3D G3DSA:3.90.940.10 27 100 1.9E-31 T 06-07-2017 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CAK77_RS13800 3e69d361c20034080787f1d04bda5e47 102 SUPERFAMILY SSF63562 27 98 7.32E-21 T 06-07-2017 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CAK77_RS13800 3e69d361c20034080787f1d04bda5e47 102 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 27 97 2.7E-25 T 06-07-2017 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK77_RS03025 3f0c3a33e985be6eeea3fb904805c395 350 Gene3D G3DSA:3.40.50.80 104 230 1.2E-29 T 06-07-2017 CAK77_RS03025 3f0c3a33e985be6eeea3fb904805c395 350 Gene3D G3DSA:2.40.30.10 10 103 8.1E-26 T 06-07-2017 CAK77_RS03025 3f0c3a33e985be6eeea3fb904805c395 350 SUPERFAMILY SSF63380 10 111 1.86E-22 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CAK77_RS03025 3f0c3a33e985be6eeea3fb904805c395 350 PRINTS PR00410 Phenol hydroxylase reductase family signature 205 213 1.8E-11 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 CAK77_RS03025 3f0c3a33e985be6eeea3fb904805c395 350 PRINTS PR00410 Phenol hydroxylase reductase family signature 42 54 1.8E-11 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 CAK77_RS03025 3f0c3a33e985be6eeea3fb904805c395 350 PRINTS PR00410 Phenol hydroxylase reductase family signature 106 115 1.8E-11 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 CAK77_RS03025 3f0c3a33e985be6eeea3fb904805c395 350 PRINTS PR00410 Phenol hydroxylase reductase family signature 121 140 1.8E-11 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 CAK77_RS03025 3f0c3a33e985be6eeea3fb904805c395 350 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 62 69 2.9E-7 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK77_RS03025 3f0c3a33e985be6eeea3fb904805c395 350 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 121 140 2.9E-7 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK77_RS03025 3f0c3a33e985be6eeea3fb904805c395 350 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 42 52 2.9E-7 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK77_RS03025 3f0c3a33e985be6eeea3fb904805c395 350 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 145 154 2.9E-7 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK77_RS03025 3f0c3a33e985be6eeea3fb904805c395 350 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 266 339 6.6E-13 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK77_RS03025 3f0c3a33e985be6eeea3fb904805c395 350 Gene3D G3DSA:3.10.20.30 231 349 1.8E-31 T 06-07-2017 IPR012675 Beta-grasp domain CAK77_RS03025 3f0c3a33e985be6eeea3fb904805c395 350 SUPERFAMILY SSF52343 103 235 7.99E-31 T 06-07-2017 CAK77_RS03025 3f0c3a33e985be6eeea3fb904805c395 350 Pfam PF00175 Oxidoreductase NAD-binding domain 122 217 1.2E-12 T 06-07-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CAK77_RS03025 3f0c3a33e985be6eeea3fb904805c395 350 SUPERFAMILY SSF54292 227 347 2.49E-27 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK77_RS03025 3f0c3a33e985be6eeea3fb904805c395 350 Pfam PF00970 Oxidoreductase FAD-binding domain 14 111 3.8E-11 T 06-07-2017 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 CAK77_RS05750 0347ec23c91b62d875d6833d20e0401a 415 Pfam PF04261 Dyp-type peroxidase family 69 403 1.1E-99 T 06-07-2017 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 CAK77_RS05750 0347ec23c91b62d875d6833d20e0401a 415 TIGRFAM TIGR01412 tat_substr_1: Tat-translocated enzyme 7 414 8.7E-134 T 06-07-2017 IPR006313 Deferrochelatase/peroxidase EfeB GO:0004601|GO:0015684|GO:0020037|GO:0033212 CAK77_RS05750 0347ec23c91b62d875d6833d20e0401a 415 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 10 37 7.5E-4 T 06-07-2017 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal CAK77_RS05750 0347ec23c91b62d875d6833d20e0401a 415 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 60 403 5.6E-90 T 06-07-2017 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 CAK77_RS05750 0347ec23c91b62d875d6833d20e0401a 415 SUPERFAMILY SSF54909 53 409 2.15E-89 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAK77_RS05750 0347ec23c91b62d875d6833d20e0401a 415 Pfam PF10518 TAT (twin-arginine translocation) pathway signal sequence 10 32 1.0E-5 T 06-07-2017 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal CAK77_RS14330 ea2f4cb94f83dc8d0894136313d109bf 214 Gene3D G3DSA:3.40.50.2300 1 146 1.6E-33 T 06-07-2017 CAK77_RS14330 ea2f4cb94f83dc8d0894136313d109bf 214 ProSitePatterns PS00622 LuxR-type HTH domain signature. 163 190 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK77_RS14330 ea2f4cb94f83dc8d0894136313d109bf 214 Pfam PF00072 Response regulator receiver domain 4 116 2.1E-25 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK77_RS14330 ea2f4cb94f83dc8d0894136313d109bf 214 Gene3D G3DSA:1.10.10.10 147 205 5.4E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS14330 ea2f4cb94f83dc8d0894136313d109bf 214 SMART SM00421 146 203 1.9E-21 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK77_RS14330 ea2f4cb94f83dc8d0894136313d109bf 214 SMART SM00448 2 115 7.3E-27 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK77_RS14330 ea2f4cb94f83dc8d0894136313d109bf 214 SUPERFAMILY SSF52172 1 128 3.27E-29 T 06-07-2017 IPR011006 CheY-like superfamily CAK77_RS14330 ea2f4cb94f83dc8d0894136313d109bf 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 149 163 4.2E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK77_RS14330 ea2f4cb94f83dc8d0894136313d109bf 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 179 4.2E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK77_RS14330 ea2f4cb94f83dc8d0894136313d109bf 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 191 4.2E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK77_RS14330 ea2f4cb94f83dc8d0894136313d109bf 214 SUPERFAMILY SSF46894 135 205 8.84E-17 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAK77_RS14330 ea2f4cb94f83dc8d0894136313d109bf 214 Pfam PF00196 Bacterial regulatory proteins, luxR family 149 203 3.7E-15 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK77_RS19870 ff02f458f6c9394d94bbf48b083d8e30 314 Gene3D G3DSA:3.40.50.720 7 254 4.2E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS19870 ff02f458f6c9394d94bbf48b083d8e30 314 Pfam PF00106 short chain dehydrogenase 10 145 6.7E-14 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS19870 ff02f458f6c9394d94bbf48b083d8e30 314 SUPERFAMILY SSF51735 7 256 4.33E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS19870 ff02f458f6c9394d94bbf48b083d8e30 314 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 197 5.7E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS19870 ff02f458f6c9394d94bbf48b083d8e30 314 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 5.7E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS19870 ff02f458f6c9394d94bbf48b083d8e30 314 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 5.7E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS18395 b39ca02d81395cfee833965b21a6f5c3 216 SUPERFAMILY SSF55469 8 213 2.62E-31 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CAK77_RS18395 b39ca02d81395cfee833965b21a6f5c3 216 Pfam PF00881 Nitroreductase family 15 184 1.8E-20 T 06-07-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 CAK77_RS18395 b39ca02d81395cfee833965b21a6f5c3 216 Gene3D G3DSA:3.40.109.10 7 216 5.9E-32 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CAK77_RS20050 ad3809d28e4ec91a1f44f3d879c8daac 354 SUPERFAMILY SSF51735 12 321 1.44E-37 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS20050 ad3809d28e4ec91a1f44f3d879c8daac 354 Gene3D G3DSA:3.40.50.720 13 315 3.5E-33 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS20050 ad3809d28e4ec91a1f44f3d879c8daac 354 Pfam PF01370 NAD dependent epimerase/dehydratase family 14 195 1.5E-20 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 CAK77_RS01495 145db44f33ae667da393787f839e3415 460 SUPERFAMILY SSF48557 22 456 1.04E-85 T 06-07-2017 IPR008948 L-Aspartase-like GO:0003824 CAK77_RS01495 145db44f33ae667da393787f839e3415 460 PRINTS PR00149 Fumarate lyase superfamily signature 244 271 2.1E-13 T 06-07-2017 IPR000362 Fumarate lyase family CAK77_RS01495 145db44f33ae667da393787f839e3415 460 PRINTS PR00149 Fumarate lyase superfamily signature 289 305 2.1E-13 T 06-07-2017 IPR000362 Fumarate lyase family CAK77_RS01495 145db44f33ae667da393787f839e3415 460 PRINTS PR00149 Fumarate lyase superfamily signature 149 167 2.1E-13 T 06-07-2017 IPR000362 Fumarate lyase family CAK77_RS01495 145db44f33ae667da393787f839e3415 460 PRINTS PR00149 Fumarate lyase superfamily signature 104 122 2.1E-13 T 06-07-2017 IPR000362 Fumarate lyase family CAK77_RS01495 145db44f33ae667da393787f839e3415 460 SMART SM00998 377 456 8.5E-10 T 06-07-2017 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CAK77_RS01495 145db44f33ae667da393787f839e3415 460 Pfam PF00206 Lyase 29 312 3.2E-29 T 06-07-2017 IPR022761 Fumarate lyase, N-terminal CAK77_RS01495 145db44f33ae667da393787f839e3415 460 Gene3D G3DSA:1.10.40.30 383 456 5.4E-18 T 06-07-2017 CAK77_RS01495 145db44f33ae667da393787f839e3415 460 Gene3D G3DSA:1.10.275.10 15 106 1.1E-24 T 06-07-2017 IPR024083 Fumarase/histidase, N-terminal CAK77_RS01495 145db44f33ae667da393787f839e3415 460 Gene3D G3DSA:1.20.200.10 107 382 8.2E-83 T 06-07-2017 CAK77_RS01495 145db44f33ae667da393787f839e3415 460 Pfam PF10397 Adenylosuccinate lyase C-terminus 381 454 6.8E-11 T 06-07-2017 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CAK77_RS16220 bbc67c3852badb3dd6db7c1c38619a4f 161 Gene3D G3DSA:3.40.50.620 2 153 9.2E-53 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS16220 bbc67c3852badb3dd6db7c1c38619a4f 161 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 4 63 4.0E-18 T 06-07-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CAK77_RS16220 bbc67c3852badb3dd6db7c1c38619a4f 161 SUPERFAMILY SSF52374 1 153 7.51E-43 T 06-07-2017 CAK77_RS16220 bbc67c3852badb3dd6db7c1c38619a4f 161 Pfam PF01467 Cytidylyltransferase-like 6 131 7.6E-21 T 06-07-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CAK77_RS16220 bbc67c3852badb3dd6db7c1c38619a4f 161 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 2 157 33.742 T 06-07-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 CAK77_RS16220 bbc67c3852badb3dd6db7c1c38619a4f 161 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 4 154 9.4E-59 T 06-07-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 CAK77_RS16220 bbc67c3852badb3dd6db7c1c38619a4f 161 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 85 101 3.1E-53 T 06-07-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 CAK77_RS16220 bbc67c3852badb3dd6db7c1c38619a4f 161 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 20 41 3.1E-53 T 06-07-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 CAK77_RS16220 bbc67c3852badb3dd6db7c1c38619a4f 161 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 2 20 3.1E-53 T 06-07-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 CAK77_RS16220 bbc67c3852badb3dd6db7c1c38619a4f 161 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 49 73 3.1E-53 T 06-07-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 CAK77_RS16220 bbc67c3852badb3dd6db7c1c38619a4f 161 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 111 133 3.1E-53 T 06-07-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 CAK77_RS16220 bbc67c3852badb3dd6db7c1c38619a4f 161 ProDom PD016147 LIGASE LYASE CITRATE PRO-3S-LYASE SYNTHETASE TRANSFERASE CYTIDYLTRANSFERASE-RELATED:CITRATE ACETATE:SH-CITRATE CITC PLASMID 11 74 1.0E-5 T 06-07-2017 CAK77_RS14435 debe81377b46c1e96fc9a1fed7f540ef 895 PRINTS PR01836 Magnesium-transporting ATPase signature 673 684 1.8E-40 T 06-07-2017 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 CAK77_RS14435 debe81377b46c1e96fc9a1fed7f540ef 895 PRINTS PR01836 Magnesium-transporting ATPase signature 705 718 1.8E-40 T 06-07-2017 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 CAK77_RS14435 debe81377b46c1e96fc9a1fed7f540ef 895 PRINTS PR01836 Magnesium-transporting ATPase signature 725 741 1.8E-40 T 06-07-2017 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 CAK77_RS14435 debe81377b46c1e96fc9a1fed7f540ef 895 PRINTS PR01836 Magnesium-transporting ATPase signature 756 777 1.8E-40 T 06-07-2017 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 CAK77_RS14435 debe81377b46c1e96fc9a1fed7f540ef 895 PRINTS PR01836 Magnesium-transporting ATPase signature 806 827 1.8E-40 T 06-07-2017 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 CAK77_RS14435 debe81377b46c1e96fc9a1fed7f540ef 895 PRINTS PR01836 Magnesium-transporting ATPase signature 655 670 1.8E-40 T 06-07-2017 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 CAK77_RS14435 debe81377b46c1e96fc9a1fed7f540ef 895 PRINTS PR01836 Magnesium-transporting ATPase signature 268 287 1.8E-40 T 06-07-2017 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 CAK77_RS14435 debe81377b46c1e96fc9a1fed7f540ef 895 PRINTS PR01836 Magnesium-transporting ATPase signature 251 267 1.8E-40 T 06-07-2017 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 CAK77_RS14435 debe81377b46c1e96fc9a1fed7f540ef 895 SUPERFAMILY SSF81665 239 332 1.44E-88 T 06-07-2017 CAK77_RS14435 debe81377b46c1e96fc9a1fed7f540ef 895 SUPERFAMILY SSF81665 646 847 1.44E-88 T 06-07-2017 CAK77_RS14435 debe81377b46c1e96fc9a1fed7f540ef 895 SUPERFAMILY SSF81665 24 130 1.44E-88 T 06-07-2017 CAK77_RS14435 debe81377b46c1e96fc9a1fed7f540ef 895 Pfam PF00702 haloacid dehalogenase-like hydrolase 334 611 2.2E-19 T 06-07-2017 CAK77_RS14435 debe81377b46c1e96fc9a1fed7f540ef 895 SUPERFAMILY SSF81653 130 237 1.83E-26 T 06-07-2017 CAK77_RS14435 debe81377b46c1e96fc9a1fed7f540ef 895 SMART SM00831 20 92 1.5E-10 T 06-07-2017 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 CAK77_RS14435 debe81377b46c1e96fc9a1fed7f540ef 895 TIGRFAM TIGR01524 ATPase-IIIB_Mg: magnesium-translocating P-type ATPase 24 847 7.7E-225 T 06-07-2017 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 CAK77_RS14435 debe81377b46c1e96fc9a1fed7f540ef 895 Pfam PF00690 Cation transporter/ATPase, N-terminus 24 87 1.4E-13 T 06-07-2017 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 CAK77_RS14435 debe81377b46c1e96fc9a1fed7f540ef 895 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 340 346 - T 06-07-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CAK77_RS14435 debe81377b46c1e96fc9a1fed7f540ef 895 Pfam PF00689 Cation transporting ATPase, C-terminus 680 843 2.6E-13 T 06-07-2017 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 CAK77_RS14435 debe81377b46c1e96fc9a1fed7f540ef 895 Gene3D G3DSA:2.70.150.10 125 237 9.3E-32 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 CAK77_RS14435 debe81377b46c1e96fc9a1fed7f540ef 895 Gene3D G3DSA:2.70.150.10 36 71 9.3E-32 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 CAK77_RS14435 debe81377b46c1e96fc9a1fed7f540ef 895 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 566 687 2.3E-26 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CAK77_RS14435 debe81377b46c1e96fc9a1fed7f540ef 895 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 222 356 9.7E-22 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CAK77_RS14435 debe81377b46c1e96fc9a1fed7f540ef 895 Gene3D G3DSA:3.40.1110.10 329 453 8.0E-20 T 06-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CAK77_RS14435 debe81377b46c1e96fc9a1fed7f540ef 895 Pfam PF00122 E1-E2 ATPase 98 329 4.9E-51 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 CAK77_RS14435 debe81377b46c1e96fc9a1fed7f540ef 895 SUPERFAMILY SSF56784 454 696 2.03E-37 T 06-07-2017 IPR023214 HAD-like domain CAK77_RS14435 debe81377b46c1e96fc9a1fed7f540ef 895 SUPERFAMILY SSF56784 336 356 2.03E-37 T 06-07-2017 IPR023214 HAD-like domain CAK77_RS14435 debe81377b46c1e96fc9a1fed7f540ef 895 Gene3D G3DSA:1.20.1110.10 72 124 3.4E-66 T 06-07-2017 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CAK77_RS14435 debe81377b46c1e96fc9a1fed7f540ef 895 Gene3D G3DSA:1.20.1110.10 566 845 3.4E-66 T 06-07-2017 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CAK77_RS05615 a153aba90f6b8bb004dbdaf988e66d09 267 SUPERFAMILY SSF56112 8 260 2.83E-57 T 06-07-2017 IPR011009 Protein kinase-like domain CAK77_RS05615 a153aba90f6b8bb004dbdaf988e66d09 267 Gene3D G3DSA:1.10.510.10 67 259 5.7E-42 T 06-07-2017 CAK77_RS05615 a153aba90f6b8bb004dbdaf988e66d09 267 Pfam PF00069 Protein kinase domain 13 252 9.6E-41 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CAK77_RS05615 a153aba90f6b8bb004dbdaf988e66d09 267 SMART SM00220 11 267 1.7E-39 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CAK77_RS05615 a153aba90f6b8bb004dbdaf988e66d09 267 Gene3D G3DSA:3.30.200.20 10 66 1.1E-14 T 06-07-2017 CAK77_RS05615 a153aba90f6b8bb004dbdaf988e66d09 267 PIRSF PIRSF000654 30 267 8.7E-18 T 06-07-2017 CAK77_RS15655 f22d7a0c601a6627b4ba00840668d2d1 2093 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 1432 1490 4.1E-6 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAK77_RS15655 f22d7a0c601a6627b4ba00840668d2d1 2093 Gene3D G3DSA:3.90.180.10 1420 1548 9.0E-41 T 06-07-2017 IPR011032 GroES-like CAK77_RS15655 f22d7a0c601a6627b4ba00840668d2d1 2093 SUPERFAMILY SSF51735 1181 1385 1.54E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS15655 f22d7a0c601a6627b4ba00840668d2d1 2093 Pfam PF00550 Phosphopantetheine attachment site 2016 2079 3.1E-9 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS15655 f22d7a0c601a6627b4ba00840668d2d1 2093 SUPERFAMILY SSF53901 7 376 1.43E-92 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS15655 f22d7a0c601a6627b4ba00840668d2d1 2093 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 8 256 2.0E-87 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAK77_RS15655 f22d7a0c601a6627b4ba00840668d2d1 2093 Gene3D G3DSA:3.40.47.10 269 432 1.1E-52 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS15655 f22d7a0c601a6627b4ba00840668d2d1 2093 Pfam PF00107 Zinc-binding dehydrogenase 1555 1645 1.1E-21 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAK77_RS15655 f22d7a0c601a6627b4ba00840668d2d1 2093 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 388 494 3.4E-10 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAK77_RS15655 f22d7a0c601a6627b4ba00840668d2d1 2093 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 264 377 8.6E-39 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAK77_RS15655 f22d7a0c601a6627b4ba00840668d2d1 2093 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 169 185 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site CAK77_RS15655 f22d7a0c601a6627b4ba00840668d2d1 2093 SUPERFAMILY SSF50129 1414 1549 2.89E-29 T 06-07-2017 IPR011032 GroES-like CAK77_RS15655 f22d7a0c601a6627b4ba00840668d2d1 2093 SUPERFAMILY SSF47336 2008 2088 2.36E-12 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS15655 f22d7a0c601a6627b4ba00840668d2d1 2093 Pfam PF14765 Polyketide synthase dehydratase 894 1175 1.9E-54 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAK77_RS15655 f22d7a0c601a6627b4ba00840668d2d1 2093 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1750 1930 5.3E-50 T 06-07-2017 CAK77_RS15655 f22d7a0c601a6627b4ba00840668d2d1 2093 SUPERFAMILY SSF51735 1520 1681 3.0E-41 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS15655 f22d7a0c601a6627b4ba00840668d2d1 2093 Gene3D G3DSA:3.40.47.10 5 268 5.8E-92 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS15655 f22d7a0c601a6627b4ba00840668d2d1 2093 Gene3D G3DSA:3.40.50.720 1549 1642 9.1E-26 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS15655 f22d7a0c601a6627b4ba00840668d2d1 2093 SUPERFAMILY SSF160904 456 545 5.23E-5 T 06-07-2017 CAK77_RS15655 f22d7a0c601a6627b4ba00840668d2d1 2093 SMART SM00823 Phosphopantetheine attachment site 2015 2083 7.0E-9 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAK77_RS15655 f22d7a0c601a6627b4ba00840668d2d1 2093 Gene3D G3DSA:3.40.50.720 1749 1953 7.6E-35 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS15655 f22d7a0c601a6627b4ba00840668d2d1 2093 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 535 830 1.1E-92 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain CAK77_RS15655 f22d7a0c601a6627b4ba00840668d2d1 2093 Pfam PF00698 Acyl transferase domain 533 847 1.2E-99 T 06-07-2017 IPR014043 Acyl transferase CAK77_RS15655 f22d7a0c601a6627b4ba00840668d2d1 2093 SUPERFAMILY SSF55048 656 721 2.35E-8 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CAK77_RS15655 f22d7a0c601a6627b4ba00840668d2d1 2093 SUPERFAMILY SSF51735 1747 1977 4.0E-39 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS15655 f22d7a0c601a6627b4ba00840668d2d1 2093 SMART SM00826 894 1055 4.1E-34 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAK77_RS15655 f22d7a0c601a6627b4ba00840668d2d1 2093 Gene3D G3DSA:1.10.1200.10 2011 2085 6.9E-14 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS15655 f22d7a0c601a6627b4ba00840668d2d1 2093 Pfam PF08659 KR domain 1750 1929 3.2E-58 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAK77_RS15655 f22d7a0c601a6627b4ba00840668d2d1 2093 Gene3D G3DSA:3.40.366.10 527 651 8.6E-66 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAK77_RS15655 f22d7a0c601a6627b4ba00840668d2d1 2093 Gene3D G3DSA:3.40.366.10 720 823 8.6E-66 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAK77_RS15655 f22d7a0c601a6627b4ba00840668d2d1 2093 SMART SM00825 Beta-ketoacyl synthase 9 431 4.3E-180 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAK77_RS15655 f22d7a0c601a6627b4ba00840668d2d1 2093 SUPERFAMILY SSF52151 722 822 2.14E-63 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAK77_RS15655 f22d7a0c601a6627b4ba00840668d2d1 2093 SUPERFAMILY SSF52151 533 657 2.14E-63 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAK77_RS15655 f22d7a0c601a6627b4ba00840668d2d1 2093 SMART SM00829 1415 1726 1.3E-146 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAK77_RS09945 c2688c754d81782d55019a977020ac5d 462 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 401 410 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CAK77_RS09945 c2688c754d81782d55019a977020ac5d 462 Gene3D G3DSA:1.10.630.10 63 460 1.3E-102 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS09945 c2688c754d81782d55019a977020ac5d 462 SUPERFAMILY SSF48264 67 459 4.06E-80 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS09945 c2688c754d81782d55019a977020ac5d 462 Pfam PF00067 Cytochrome P450 329 432 2.3E-16 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS09945 c2688c754d81782d55019a977020ac5d 462 PRINTS PR00359 B-class P450 signature 201 216 5.8E-29 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS09945 c2688c754d81782d55019a977020ac5d 462 PRINTS PR00359 B-class P450 signature 332 343 5.8E-29 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS09945 c2688c754d81782d55019a977020ac5d 462 PRINTS PR00359 B-class P450 signature 408 419 5.8E-29 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS09945 c2688c754d81782d55019a977020ac5d 462 PRINTS PR00359 B-class P450 signature 349 376 5.8E-29 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS09945 c2688c754d81782d55019a977020ac5d 462 PRINTS PR00359 B-class P450 signature 399 408 5.8E-29 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS09945 c2688c754d81782d55019a977020ac5d 462 PRINTS PR00359 B-class P450 signature 138 149 5.8E-29 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS09945 c2688c754d81782d55019a977020ac5d 462 PRINTS PR00359 B-class P450 signature 377 392 5.8E-29 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS05150 c55e780c57cb64de2daa82c53ab7a08a 369 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 47 289 4.6E-29 T 06-07-2017 IPR018713 Domain of unknown function DUF2236 CAK77_RS17880 0bfb6547c41e79d89fb3f1bf18b6c171 486 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 266 282 - T 06-07-2017 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CAK77_RS17880 0bfb6547c41e79d89fb3f1bf18b6c171 486 SMART SM00997 244 406 1.0E-102 T 06-07-2017 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CAK77_RS17880 0bfb6547c41e79d89fb3f1bf18b6c171 486 Gene3D G3DSA:3.40.50.1480 13 245 6.2E-142 T 06-07-2017 CAK77_RS17880 0bfb6547c41e79d89fb3f1bf18b6c171 486 Gene3D G3DSA:3.40.50.1480 407 486 6.2E-142 T 06-07-2017 CAK77_RS17880 0bfb6547c41e79d89fb3f1bf18b6c171 486 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 85 99 - T 06-07-2017 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CAK77_RS17880 0bfb6547c41e79d89fb3f1bf18b6c171 486 SUPERFAMILY SSF51735 244 406 2.2E-68 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS17880 0bfb6547c41e79d89fb3f1bf18b6c171 486 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 244 406 1.8E-77 T 06-07-2017 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CAK77_RS17880 0bfb6547c41e79d89fb3f1bf18b6c171 486 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 9 478 47.189 T 06-07-2017 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CAK77_RS17880 0bfb6547c41e79d89fb3f1bf18b6c171 486 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 13 485 8.8E-146 T 06-07-2017 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CAK77_RS17880 0bfb6547c41e79d89fb3f1bf18b6c171 486 SMART SM00996 13 485 0.0 T 06-07-2017 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CAK77_RS17880 0bfb6547c41e79d89fb3f1bf18b6c171 486 SUPERFAMILY SSF52283 196 243 1.25E-109 T 06-07-2017 CAK77_RS17880 0bfb6547c41e79d89fb3f1bf18b6c171 486 SUPERFAMILY SSF52283 12 158 1.25E-109 T 06-07-2017 CAK77_RS17880 0bfb6547c41e79d89fb3f1bf18b6c171 486 SUPERFAMILY SSF52283 407 486 1.25E-109 T 06-07-2017 CAK77_RS17880 0bfb6547c41e79d89fb3f1bf18b6c171 486 Gene3D G3DSA:3.40.50.720 246 405 1.8E-47 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS17880 0bfb6547c41e79d89fb3f1bf18b6c171 486 PIRSF PIRSF001109 1 486 1.9E-192 T 06-07-2017 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CAK77_RS17880 0bfb6547c41e79d89fb3f1bf18b6c171 486 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 14 478 1.5E-198 T 06-07-2017 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CAK77_RS19860 c3d10fd0acaa1467cb6404c951064ac5 461 Pfam PF06974 Protein of unknown function (DUF1298) 301 449 9.4E-21 T 06-07-2017 IPR009721 O-acyltransferase WSD1, C-terminal GO:0004144 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CAK77_RS19860 c3d10fd0acaa1467cb6404c951064ac5 461 TIGRFAM TIGR02946 acyl_WS_DGAT: acyltransferase, WS/DGAT/MGAT 4 452 1.6E-108 T 06-07-2017 IPR014292 Acyltransferase, WS/DGAT/MGAT GO:0016746|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CAK77_RS19860 c3d10fd0acaa1467cb6404c951064ac5 461 Pfam PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain 4 260 7.7E-52 T 06-07-2017 IPR004255 O-acyltransferase, WSD1, N-terminal GO:0004144|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CAK77_RS16600 a7b57f025f09c2d813b34795c667115a 249 Gene3D G3DSA:1.10.10.10 152 245 7.2E-34 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS16600 a7b57f025f09c2d813b34795c667115a 249 SMART SM00448 16 126 2.1E-41 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK77_RS16600 a7b57f025f09c2d813b34795c667115a 249 SMART SM00862 169 245 5.6E-27 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAK77_RS16600 a7b57f025f09c2d813b34795c667115a 249 Pfam PF00486 Transcriptional regulatory protein, C terminal 170 245 4.8E-27 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAK77_RS16600 a7b57f025f09c2d813b34795c667115a 249 Gene3D G3DSA:3.40.50.2300 15 135 4.3E-37 T 06-07-2017 CAK77_RS16600 a7b57f025f09c2d813b34795c667115a 249 Pfam PF00072 Response regulator receiver domain 19 126 3.6E-27 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK77_RS16600 a7b57f025f09c2d813b34795c667115a 249 SUPERFAMILY SSF46894 150 245 1.81E-29 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAK77_RS16600 a7b57f025f09c2d813b34795c667115a 249 SUPERFAMILY SSF52172 13 138 4.27E-40 T 06-07-2017 IPR011006 CheY-like superfamily CAK77_RS09445 b6801c80c2599da5e4e72d560d1f5ff0 578 Gene3D G3DSA:3.30.559.10 337 569 2.8E-78 T 06-07-2017 IPR023213 Chloramphenicol acetyltransferase-like domain Reactome: R-HSA-389661 CAK77_RS09445 b6801c80c2599da5e4e72d560d1f5ff0 578 Gene3D G3DSA:2.40.50.100 1 95 5.2E-31 T 06-07-2017 CAK77_RS09445 b6801c80c2599da5e4e72d560d1f5ff0 578 Gene3D G3DSA:2.40.50.100 126 219 8.6E-29 T 06-07-2017 CAK77_RS09445 b6801c80c2599da5e4e72d560d1f5ff0 578 SUPERFAMILY SSF52777 329 569 2.4E-75 T 06-07-2017 CAK77_RS09445 b6801c80c2599da5e4e72d560d1f5ff0 578 SUPERFAMILY SSF47005 266 308 2.22E-11 T 06-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CAK77_RS09445 b6801c80c2599da5e4e72d560d1f5ff0 578 TIGRFAM TIGR02927 SucB_Actino: 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase 1 578 1.2E-279 T 06-07-2017 IPR014276 2-oxoglutarate dehydrogenase, E2 component KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00620+2.3.1.12 CAK77_RS09445 b6801c80c2599da5e4e72d560d1f5ff0 578 SUPERFAMILY SSF51230 1 96 4.06E-28 T 06-07-2017 IPR011053 Single hybrid motif CAK77_RS09445 b6801c80c2599da5e4e72d560d1f5ff0 578 Gene3D G3DSA:4.10.320.10 266 315 2.6E-19 T 06-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CAK77_RS09445 b6801c80c2599da5e4e72d560d1f5ff0 578 SUPERFAMILY SSF51230 126 218 3.27E-26 T 06-07-2017 IPR011053 Single hybrid motif CAK77_RS09445 b6801c80c2599da5e4e72d560d1f5ff0 578 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 342 569 6.5E-73 T 06-07-2017 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CAK77_RS09445 b6801c80c2599da5e4e72d560d1f5ff0 578 Pfam PF00364 Biotin-requiring enzyme 127 198 1.8E-20 T 06-07-2017 IPR000089 Biotin/lipoyl attachment CAK77_RS09445 b6801c80c2599da5e4e72d560d1f5ff0 578 Pfam PF00364 Biotin-requiring enzyme 5 76 4.9E-21 T 06-07-2017 IPR000089 Biotin/lipoyl attachment CAK77_RS09445 b6801c80c2599da5e4e72d560d1f5ff0 578 Pfam PF02817 e3 binding domain 270 304 1.2E-14 T 06-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CAK77_RS09445 b6801c80c2599da5e4e72d560d1f5ff0 578 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 06-07-2017 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CAK77_RS09445 b6801c80c2599da5e4e72d560d1f5ff0 578 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 150 179 - T 06-07-2017 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CAK77_RS18795 9af1cb02987410b51a6fb81fcbbe04d7 294 Pfam PF01416 tRNA pseudouridine synthase 172 273 4.3E-21 T 06-07-2017 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAK77_RS18795 9af1cb02987410b51a6fb81fcbbe04d7 294 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 16 272 30.46 T 06-07-2017 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAK77_RS18795 9af1cb02987410b51a6fb81fcbbe04d7 294 Gene3D G3DSA:3.30.70.660 135 270 6.8E-35 T 06-07-2017 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAK77_RS18795 9af1cb02987410b51a6fb81fcbbe04d7 294 Gene3D G3DSA:3.30.70.580 17 133 2.6E-32 T 06-07-2017 IPR020094 Pseudouridine synthase I, TruA, N-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAK77_RS18795 9af1cb02987410b51a6fb81fcbbe04d7 294 PIRSF PIRSF001430 15 289 1.4E-68 T 06-07-2017 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAK77_RS18795 9af1cb02987410b51a6fb81fcbbe04d7 294 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 19 267 7.1E-49 T 06-07-2017 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAK77_RS18795 9af1cb02987410b51a6fb81fcbbe04d7 294 SUPERFAMILY SSF55120 16 281 1.73E-71 T 06-07-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAK77_RS17335 8b4500cc8928365c20e81ff5cf9ce0fe 97 Pfam PF07553 Host cell surface-exposed lipoprotein 6 48 4.5E-12 T 06-07-2017 IPR011434 Domain of unknown function DUF1535 CAK77_RS17335 8b4500cc8928365c20e81ff5cf9ce0fe 97 Pfam PF07553 Host cell surface-exposed lipoprotein 51 92 4.8E-14 T 06-07-2017 IPR011434 Domain of unknown function DUF1535 CAK77_RS07415 faeb3c82f5ee297e05c045d7541e60eb 434 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 135 312 1.8E-5 T 06-07-2017 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CAK77_RS07415 faeb3c82f5ee297e05c045d7541e60eb 434 TIGRFAM TIGR01513 NAPRTase_put: nicotinate phosphoribosyltransferase 7 422 1.7E-132 T 06-07-2017 IPR006405 Nicotinate phosphoribosyltransferase pncB-type GO:0004516|GO:0019358 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 CAK77_RS07415 faeb3c82f5ee297e05c045d7541e60eb 434 SUPERFAMILY SSF54675 6 133 7.54E-38 T 06-07-2017 CAK77_RS07415 faeb3c82f5ee297e05c045d7541e60eb 434 SUPERFAMILY SSF51690 135 428 3.27E-81 T 06-07-2017 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CAK77_RS07415 faeb3c82f5ee297e05c045d7541e60eb 434 Gene3D G3DSA:3.20.140.10 6 372 4.6E-91 T 06-07-2017 CAK77_RS07415 faeb3c82f5ee297e05c045d7541e60eb 434 PIRSF PIRSF000484 1 421 2.3E-103 T 06-07-2017 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 CAK77_RS00245 66c4dc4b370b07165b43bb6ed57e0464 186 SUPERFAMILY SSF53056 7 175 2.35E-32 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CAK77_RS00245 66c4dc4b370b07165b43bb6ed57e0464 186 SMART SM00947 8 176 4.6E-18 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CAK77_RS00245 66c4dc4b370b07165b43bb6ed57e0464 186 Pfam PF00484 Carbonic anhydrase 16 167 1.1E-28 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CAK77_RS00245 66c4dc4b370b07165b43bb6ed57e0464 186 Gene3D G3DSA:3.40.1050.10 10 175 2.6E-35 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CAK77_RS02005 aed150326e5f918f02829f2e962fa35a 1081 Gene3D G3DSA:1.10.486.10 449 589 6.6E-30 T 06-07-2017 CAK77_RS02005 aed150326e5f918f02829f2e962fa35a 1081 Pfam PF00580 UvrD/REP helicase N-terminal domain 15 307 1.8E-52 T 06-07-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 CAK77_RS02005 aed150326e5f918f02829f2e962fa35a 1081 Gene3D G3DSA:3.40.50.300 115 175 8.5E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS02005 aed150326e5f918f02829f2e962fa35a 1081 Gene3D G3DSA:3.40.50.300 211 312 8.5E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS02005 aed150326e5f918f02829f2e962fa35a 1081 Gene3D G3DSA:3.40.50.300 13 66 8.5E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS02005 aed150326e5f918f02829f2e962fa35a 1081 Pfam PF13361 UvrD-like helicase C-terminal domain 544 680 4.9E-9 T 06-07-2017 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CAK77_RS02005 aed150326e5f918f02829f2e962fa35a 1081 SUPERFAMILY SSF52980 769 1080 8.04E-60 T 06-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CAK77_RS02005 aed150326e5f918f02829f2e962fa35a 1081 TIGRFAM TIGR00609 recB: exodeoxyribonuclease V, beta subunit 203 1080 5.6E-213 T 06-07-2017 IPR004586 RecBCD enzyme subunit RecB GO:0005524|GO:0006281|GO:0008854 CAK77_RS02005 aed150326e5f918f02829f2e962fa35a 1081 SUPERFAMILY SSF52540 107 354 4.96E-87 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS02005 aed150326e5f918f02829f2e962fa35a 1081 SUPERFAMILY SSF52540 661 687 4.96E-87 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS02005 aed150326e5f918f02829f2e962fa35a 1081 SUPERFAMILY SSF52540 14 70 4.96E-87 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS02005 aed150326e5f918f02829f2e962fa35a 1081 SUPERFAMILY SSF52540 391 634 4.96E-87 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS02005 aed150326e5f918f02829f2e962fa35a 1081 Hamap MF_01485 RecBCD enzyme subunit RecB [recB]. 2 1081 16.372 T 06-07-2017 IPR004586 RecBCD enzyme subunit RecB GO:0005524|GO:0006281|GO:0008854 CAK77_RS02005 aed150326e5f918f02829f2e962fa35a 1081 Gene3D G3DSA:3.40.50.300 317 445 1.6E-40 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS02005 aed150326e5f918f02829f2e962fa35a 1081 Gene3D G3DSA:3.40.50.300 590 719 1.6E-40 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS02005 aed150326e5f918f02829f2e962fa35a 1081 Gene3D G3DSA:3.90.320.10 759 1081 5.5E-73 T 06-07-2017 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 CAK77_RS23220 fe363976cb9baea4c256543ecae4d5ac 262 SUPERFAMILY SSF51735 3 257 7.36E-65 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS23220 fe363976cb9baea4c256543ecae4d5ac 262 Pfam PF00106 short chain dehydrogenase 8 190 1.9E-43 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS23220 fe363976cb9baea4c256543ecae4d5ac 262 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK77_RS23220 fe363976cb9baea4c256543ecae4d5ac 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 2.5E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS23220 fe363976cb9baea4c256543ecae4d5ac 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 2.5E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS23220 fe363976cb9baea4c256543ecae4d5ac 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 2.5E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS23220 fe363976cb9baea4c256543ecae4d5ac 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 5.4E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS23220 fe363976cb9baea4c256543ecae4d5ac 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 5.4E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS23220 fe363976cb9baea4c256543ecae4d5ac 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 5.4E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS23220 fe363976cb9baea4c256543ecae4d5ac 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 5.4E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS23220 fe363976cb9baea4c256543ecae4d5ac 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 5.4E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS23220 fe363976cb9baea4c256543ecae4d5ac 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 220 240 5.4E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS23220 fe363976cb9baea4c256543ecae4d5ac 262 Gene3D G3DSA:3.40.50.720 4 257 1.9E-69 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS05020 30d7129d1215f9888c1f0bcb737b48ed 394 Hamap MF_03210 Formate dehydrogenase, mitochondrial. 2 383 55.187 T 06-07-2017 IPR033689 NAD-dependent formate dehydrogenase GO:0008863 KEGG: 00630+1.2.1.2|KEGG: 00680+1.2.1.2|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696 CAK77_RS05020 30d7129d1215f9888c1f0bcb737b48ed 394 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 62 363 7.1E-19 T 06-07-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CAK77_RS05020 30d7129d1215f9888c1f0bcb737b48ed 394 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 195 222 - T 06-07-2017 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 CAK77_RS05020 30d7129d1215f9888c1f0bcb737b48ed 394 SUPERFAMILY SSF51735 147 336 1.77E-50 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS05020 30d7129d1215f9888c1f0bcb737b48ed 394 Gene3D G3DSA:3.40.50.720 187 343 1.3E-28 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS05020 30d7129d1215f9888c1f0bcb737b48ed 394 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 156 335 1.2E-47 T 06-07-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CAK77_RS05020 30d7129d1215f9888c1f0bcb737b48ed 394 SUPERFAMILY SSF52283 3 177 5.32E-65 T 06-07-2017 CAK77_RS05020 30d7129d1215f9888c1f0bcb737b48ed 394 Gene3D G3DSA:3.40.50.720 2 184 2.9E-86 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS17040 86c5ca38d360a9e1bf93a5c1ca58b5d2 273 Hamap MF_00193 NH(3)-dependent NAD(+) synthetase [nadE]. 18 267 31.155 T 06-07-2017 IPR022926 NH(3)-dependent NAD(+) synthetase GO:0008795|GO:0009435 KEGG: 00760+6.3.1.5 CAK77_RS17040 86c5ca38d360a9e1bf93a5c1ca58b5d2 273 TIGRFAM TIGR00552 nadE: NAD+ synthetase 23 272 1.4E-69 T 06-07-2017 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 CAK77_RS17040 86c5ca38d360a9e1bf93a5c1ca58b5d2 273 Pfam PF02540 NAD synthase 24 264 4.1E-67 T 06-07-2017 IPR022310 NAD/GMP synthase CAK77_RS17040 86c5ca38d360a9e1bf93a5c1ca58b5d2 273 Gene3D G3DSA:3.40.50.620 6 268 1.8E-71 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS17040 86c5ca38d360a9e1bf93a5c1ca58b5d2 273 SUPERFAMILY SSF52402 5 273 1.9E-79 T 06-07-2017 CAK77_RS24445 141732195b29e565183fb7670cd19131 157 Pfam PF01230 HIT domain 45 114 6.4E-7 T 06-07-2017 IPR001310 Histidine triad (HIT) protein CAK77_RS24445 141732195b29e565183fb7670cd19131 157 SUPERFAMILY SSF54197 20 152 1.36E-22 T 06-07-2017 IPR011146 HIT-like domain GO:0003824 CAK77_RS24445 141732195b29e565183fb7670cd19131 157 Gene3D G3DSA:3.30.428.10 18 152 3.5E-24 T 06-07-2017 IPR011146 HIT-like domain GO:0003824 CAK77_RS11190 2e526da86962116770ca580361d2aac4 140 Pfam PF05423 Mycobacterium membrane protein 1 140 1.0E-55 T 06-07-2017 IPR008693 Transport accessory protein MmpS CAK77_RS04620 56ceb1c58661e2bdb8a6d0b81474b4d7 414 SUPERFAMILY SSF103473 5 399 2.62E-36 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK77_RS04620 56ceb1c58661e2bdb8a6d0b81474b4d7 414 Gene3D G3DSA:1.20.1250.20 215 398 8.0E-11 T 06-07-2017 CAK77_RS04620 56ceb1c58661e2bdb8a6d0b81474b4d7 414 Gene3D G3DSA:1.20.1250.20 3 187 2.4E-17 T 06-07-2017 CAK77_RS04620 56ceb1c58661e2bdb8a6d0b81474b4d7 414 Pfam PF05977 Transmembrane secretion effector 1 398 2.8E-30 T 06-07-2017 IPR010290 Transmembrane secretion effector CAK77_RS14325 b81247772986fa4b1466660ce76cef86 562 SUPERFAMILY SSF55781 196 381 1.22E-24 T 06-07-2017 IPR029016 GAF domain-like CAK77_RS14325 b81247772986fa4b1466660ce76cef86 562 SMART SM00065 47 194 9.8E-20 T 06-07-2017 IPR003018 GAF domain GO:0005515 CAK77_RS14325 b81247772986fa4b1466660ce76cef86 562 SMART SM00065 215 363 2.5E-10 T 06-07-2017 IPR003018 GAF domain GO:0005515 CAK77_RS14325 b81247772986fa4b1466660ce76cef86 562 Pfam PF13185 GAF domain 46 185 2.0E-18 T 06-07-2017 IPR003018 GAF domain GO:0005515 CAK77_RS14325 b81247772986fa4b1466660ce76cef86 562 Gene3D G3DSA:3.30.565.10 466 523 6.8E-9 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS14325 b81247772986fa4b1466660ce76cef86 562 Pfam PF07730 Histidine kinase 371 433 3.3E-10 T 06-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CAK77_RS14325 b81247772986fa4b1466660ce76cef86 562 Gene3D G3DSA:3.30.450.40 37 191 1.4E-29 T 06-07-2017 IPR029016 GAF domain-like CAK77_RS14325 b81247772986fa4b1466660ce76cef86 562 Pfam PF13492 GAF domain 222 355 3.2E-11 T 06-07-2017 IPR003018 GAF domain GO:0005515 CAK77_RS14325 b81247772986fa4b1466660ce76cef86 562 SUPERFAMILY SSF55781 30 211 8.72E-37 T 06-07-2017 IPR029016 GAF domain-like CAK77_RS14325 b81247772986fa4b1466660ce76cef86 562 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 478 526 4.7E-8 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS14325 b81247772986fa4b1466660ce76cef86 562 SMART SM00387 474 562 0.0039 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS14325 b81247772986fa4b1466660ce76cef86 562 SUPERFAMILY SSF55874 466 561 7.47E-16 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS14325 b81247772986fa4b1466660ce76cef86 562 Gene3D G3DSA:3.30.450.40 194 360 7.2E-22 T 06-07-2017 IPR029016 GAF domain-like CAK77_RS06780 02cb5beb79f463038d13ab704f7ca733 404 Pfam PF00483 Nucleotidyl transferase 9 276 8.7E-69 T 06-07-2017 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CAK77_RS06780 02cb5beb79f463038d13ab704f7ca733 404 SUPERFAMILY SSF53448 342 358 2.35E-70 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK77_RS06780 02cb5beb79f463038d13ab704f7ca733 404 SUPERFAMILY SSF53448 6 280 2.35E-70 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK77_RS06780 02cb5beb79f463038d13ab704f7ca733 404 TIGRFAM TIGR02091 glgC: glucose-1-phosphate adenylyltransferase 7 378 1.5E-143 T 06-07-2017 IPR011831 Glucose-1-phosphate adenylyltransferase GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 CAK77_RS06780 02cb5beb79f463038d13ab704f7ca733 404 ProSitePatterns PS00809 ADP-glucose pyrophosphorylase signature 2. 98 106 - T 06-07-2017 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 CAK77_RS06780 02cb5beb79f463038d13ab704f7ca733 404 SUPERFAMILY SSF51161 301 398 9.7E-16 T 06-07-2017 IPR011004 Trimeric LpxA-like CAK77_RS06780 02cb5beb79f463038d13ab704f7ca733 404 ProSitePatterns PS00808 ADP-glucose pyrophosphorylase signature 1. 13 32 - T 06-07-2017 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 CAK77_RS06780 02cb5beb79f463038d13ab704f7ca733 404 Gene3D G3DSA:3.90.550.10 325 368 1.4E-74 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK77_RS06780 02cb5beb79f463038d13ab704f7ca733 404 Gene3D G3DSA:3.90.550.10 9 287 1.4E-74 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK77_RS06780 02cb5beb79f463038d13ab704f7ca733 404 Hamap MF_00624 Glucose-1-phosphate adenylyltransferase [glgC]. 4 404 47.315 T 06-07-2017 IPR023049 Glucose-1-phosphate adenylyltransferase GlgC, bacterial GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 CAK77_RS06780 02cb5beb79f463038d13ab704f7ca733 404 ProSitePatterns PS00810 ADP-glucose pyrophosphorylase signature 3. 196 206 - T 06-07-2017 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 CAK77_RS07265 d6b131d3da6ae8ab2f5864e1ad937ae7 83 Gene3D G3DSA:1.20.20.10 6 80 8.1E-25 T 06-07-2017 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210 CAK77_RS07265 d6b131d3da6ae8ab2f5864e1ad937ae7 83 ProSitePatterns PS00605 ATP synthase c subunit signature. 41 62 - T 06-07-2017 IPR020537 ATPase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210 CAK77_RS07265 d6b131d3da6ae8ab2f5864e1ad937ae7 83 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 22 78 9.8E-15 T 06-07-2017 IPR005953 ATPase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 CAK77_RS07265 d6b131d3da6ae8ab2f5864e1ad937ae7 83 PRINTS PR00124 ATP synthase C subunit signature 51 76 1.5E-8 T 06-07-2017 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210 CAK77_RS07265 d6b131d3da6ae8ab2f5864e1ad937ae7 83 PRINTS PR00124 ATP synthase C subunit signature 13 32 1.5E-8 T 06-07-2017 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210 CAK77_RS07265 d6b131d3da6ae8ab2f5864e1ad937ae7 83 PRINTS PR00124 ATP synthase C subunit signature 34 49 1.5E-8 T 06-07-2017 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210 CAK77_RS07265 d6b131d3da6ae8ab2f5864e1ad937ae7 83 SUPERFAMILY SSF81333 7 79 1.57E-15 T 06-07-2017 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CAK77_RS07265 d6b131d3da6ae8ab2f5864e1ad937ae7 83 Pfam PF00137 ATP synthase subunit C 12 71 1.2E-8 T 06-07-2017 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CAK77_RS07265 d6b131d3da6ae8ab2f5864e1ad937ae7 83 Hamap MF_01396 ATP synthase subunit c [atpH]. 10 78 14.607 T 06-07-2017 CAK77_RS02900 48913ff3e204d292dbf28f6a7a02a407 280 Gene3D G3DSA:1.10.1670.10 114 202 6.3E-32 T 06-07-2017 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CAK77_RS02900 48913ff3e204d292dbf28f6a7a02a407 280 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 25 139 2.7E-15 T 06-07-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CAK77_RS02900 48913ff3e204d292dbf28f6a7a02a407 280 Gene3D G3DSA:1.10.340.30 12 113 3.9E-36 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CAK77_RS02900 48913ff3e204d292dbf28f6a7a02a407 280 SMART SM00478 29 177 1.5E-40 T 06-07-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CAK77_RS02900 48913ff3e204d292dbf28f6a7a02a407 280 Pfam PF00633 Helix-hairpin-helix motif 90 118 1.6E-7 T 06-07-2017 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 CAK77_RS02900 48913ff3e204d292dbf28f6a7a02a407 280 SUPERFAMILY SSF48150 2 196 6.28E-60 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CAK77_RS05975 51dcad2bb0bccf619a770f0004e678e0 281 Pfam PF12811 Bax inhibitor 1 like 45 280 7.7E-82 T 06-07-2017 IPR010539 Protein of unknown function UCP009160 CAK77_RS05975 51dcad2bb0bccf619a770f0004e678e0 281 PIRSF PIRSF009160 1 281 1.0E-89 T 06-07-2017 IPR010539 Protein of unknown function UCP009160 CAK77_RS09680 52074582c50be43448cd102d489af88b 520 TIGRFAM TIGR03459 crt_membr: carotene biosynthesis associated membrane protein 41 505 4.7E-179 T 06-07-2017 IPR017822 Carotene biosynthesis-associated membrane protein, type-1 CAK77_RS23025 89da4e2e2ee56401d10fdbcaa657e7f7 529 ProSitePatterns PS00455 Putative AMP-binding domain signature. 180 191 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK77_RS23025 89da4e2e2ee56401d10fdbcaa657e7f7 529 Pfam PF13193 AMP-binding enzyme C-terminal domain 434 516 1.4E-18 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAK77_RS23025 89da4e2e2ee56401d10fdbcaa657e7f7 529 Gene3D G3DSA:2.30.38.10 346 416 2.8E-25 T 06-07-2017 CAK77_RS23025 89da4e2e2ee56401d10fdbcaa657e7f7 529 Gene3D G3DSA:3.40.50.980 17 184 3.7E-13 T 06-07-2017 CAK77_RS23025 89da4e2e2ee56401d10fdbcaa657e7f7 529 Gene3D G3DSA:3.40.50.980 185 345 9.2E-36 T 06-07-2017 CAK77_RS23025 89da4e2e2ee56401d10fdbcaa657e7f7 529 SUPERFAMILY SSF56801 14 528 2.62E-124 T 06-07-2017 CAK77_RS23025 89da4e2e2ee56401d10fdbcaa657e7f7 529 Pfam PF00501 AMP-binding enzyme 23 425 8.0E-75 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK77_RS23025 89da4e2e2ee56401d10fdbcaa657e7f7 529 Gene3D G3DSA:3.30.300.30 420 526 1.7E-28 T 06-07-2017 CAK77_RS22160 80ff27b18abe11109998cb078f3b7e8e 452 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 332 348 6.1E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS22160 80ff27b18abe11109998cb078f3b7e8e 452 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 358 377 6.1E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS22160 80ff27b18abe11109998cb078f3b7e8e 452 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 412 432 6.1E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS22160 80ff27b18abe11109998cb078f3b7e8e 452 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 285 296 6.1E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS22160 80ff27b18abe11109998cb078f3b7e8e 452 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 232 6.1E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS22160 80ff27b18abe11109998cb078f3b7e8e 452 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 379 396 6.1E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS22160 80ff27b18abe11109998cb078f3b7e8e 452 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 214 389 0.0011 T 06-07-2017 CAK77_RS22160 80ff27b18abe11109998cb078f3b7e8e 452 SUPERFAMILY SSF51735 209 446 4.48E-62 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS22160 80ff27b18abe11109998cb078f3b7e8e 452 Gene3D G3DSA:3.40.50.720 210 446 7.6E-68 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS22160 80ff27b18abe11109998cb078f3b7e8e 452 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 358 377 2.4E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS22160 80ff27b18abe11109998cb078f3b7e8e 452 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 285 296 2.4E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS22160 80ff27b18abe11109998cb078f3b7e8e 452 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 338 346 2.4E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS22160 80ff27b18abe11109998cb078f3b7e8e 452 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 220 445 1.1E-51 T 06-07-2017 CAK77_RS22160 80ff27b18abe11109998cb078f3b7e8e 452 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 345 373 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK77_RS03450 1c5fd997bce45431ad5afb6ab10d37c0 96 ProDom PD020150 ESAT-6-LIKE ANTIGEN ESXR CFP7 LOW WEIGHT ESXQ CFP-7 TB10.4 MOLECULAR 2 95 4.0E-24 T 06-07-2017 CAK77_RS03450 1c5fd997bce45431ad5afb6ab10d37c0 96 Gene3D G3DSA:1.10.287.1060 2 95 1.5E-16 T 06-07-2017 CAK77_RS03450 1c5fd997bce45431ad5afb6ab10d37c0 96 SUPERFAMILY SSF140453 2 95 1.44E-18 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like CAK77_RS03450 1c5fd997bce45431ad5afb6ab10d37c0 96 Pfam PF06013 Proteins of 100 residues with WXG 3 87 2.3E-12 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like CAK77_RS03450 1c5fd997bce45431ad5afb6ab10d37c0 96 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 3 89 1.3E-13 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like CAK77_RS00410 1c5fd997bce45431ad5afb6ab10d37c0 96 ProDom PD020150 ESAT-6-LIKE ANTIGEN ESXR CFP7 LOW WEIGHT ESXQ CFP-7 TB10.4 MOLECULAR 2 95 4.0E-24 T 06-07-2017 CAK77_RS00410 1c5fd997bce45431ad5afb6ab10d37c0 96 Gene3D G3DSA:1.10.287.1060 2 95 1.5E-16 T 06-07-2017 CAK77_RS00410 1c5fd997bce45431ad5afb6ab10d37c0 96 SUPERFAMILY SSF140453 2 95 1.44E-18 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like CAK77_RS00410 1c5fd997bce45431ad5afb6ab10d37c0 96 Pfam PF06013 Proteins of 100 residues with WXG 3 87 2.3E-12 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like CAK77_RS00410 1c5fd997bce45431ad5afb6ab10d37c0 96 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 3 89 1.3E-13 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like CAK77_RS10860 1c5fd997bce45431ad5afb6ab10d37c0 96 ProDom PD020150 ESAT-6-LIKE ANTIGEN ESXR CFP7 LOW WEIGHT ESXQ CFP-7 TB10.4 MOLECULAR 2 95 4.0E-24 T 06-07-2017 CAK77_RS10860 1c5fd997bce45431ad5afb6ab10d37c0 96 Gene3D G3DSA:1.10.287.1060 2 95 1.5E-16 T 06-07-2017 CAK77_RS10860 1c5fd997bce45431ad5afb6ab10d37c0 96 SUPERFAMILY SSF140453 2 95 1.44E-18 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like CAK77_RS10860 1c5fd997bce45431ad5afb6ab10d37c0 96 Pfam PF06013 Proteins of 100 residues with WXG 3 87 2.3E-12 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like CAK77_RS10860 1c5fd997bce45431ad5afb6ab10d37c0 96 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 3 89 1.3E-13 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like CAK77_RS09940 83829e28f7e1fcb9b28c6b0b7d75a145 399 SUPERFAMILY SSF55424 314 395 1.37E-26 T 06-07-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CAK77_RS09940 83829e28f7e1fcb9b28c6b0b7d75a145 399 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 301 3.2E-63 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS09940 83829e28f7e1fcb9b28c6b0b7d75a145 399 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 146 164 6.9E-24 T 06-07-2017 CAK77_RS09940 83829e28f7e1fcb9b28c6b0b7d75a145 399 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 231 247 6.9E-24 T 06-07-2017 CAK77_RS09940 83829e28f7e1fcb9b28c6b0b7d75a145 399 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 101 119 6.9E-24 T 06-07-2017 CAK77_RS09940 83829e28f7e1fcb9b28c6b0b7d75a145 399 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 256 278 6.9E-24 T 06-07-2017 CAK77_RS09940 83829e28f7e1fcb9b28c6b0b7d75a145 399 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 6.9E-24 T 06-07-2017 CAK77_RS09940 83829e28f7e1fcb9b28c6b0b7d75a145 399 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 1.1E-15 T 06-07-2017 CAK77_RS09940 83829e28f7e1fcb9b28c6b0b7d75a145 399 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 232 246 1.1E-15 T 06-07-2017 CAK77_RS09940 83829e28f7e1fcb9b28c6b0b7d75a145 399 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 271 278 1.1E-15 T 06-07-2017 CAK77_RS09940 83829e28f7e1fcb9b28c6b0b7d75a145 399 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 146 171 1.1E-15 T 06-07-2017 CAK77_RS09940 83829e28f7e1fcb9b28c6b0b7d75a145 399 Gene3D G3DSA:3.30.390.30 320 394 1.8E-29 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CAK77_RS09940 83829e28f7e1fcb9b28c6b0b7d75a145 399 SUPERFAMILY SSF51905 5 191 3.48E-45 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS09940 83829e28f7e1fcb9b28c6b0b7d75a145 399 Gene3D G3DSA:3.50.50.60 110 310 7.7E-52 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS09940 83829e28f7e1fcb9b28c6b0b7d75a145 399 Gene3D G3DSA:3.50.50.60 4 109 3.0E-29 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS09940 83829e28f7e1fcb9b28c6b0b7d75a145 399 SUPERFAMILY SSF51905 145 310 1.04E-32 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS09940 83829e28f7e1fcb9b28c6b0b7d75a145 399 Pfam PF14759 Reductase C-terminal 320 395 5.2E-28 T 06-07-2017 IPR028202 Reductase, C-terminal CAK77_RS05250 1c67e513b92ba30440699a67c35c9eef 559 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 37 480 4.0E-148 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK77_RS05250 1c67e513b92ba30440699a67c35c9eef 559 PRINTS PR01165 Cytochrome c oxidase subunit I signature 323 344 1.3E-99 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK77_RS05250 1c67e513b92ba30440699a67c35c9eef 559 PRINTS PR01165 Cytochrome c oxidase subunit I signature 27 52 1.3E-99 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK77_RS05250 1c67e513b92ba30440699a67c35c9eef 559 PRINTS PR01165 Cytochrome c oxidase subunit I signature 301 316 1.3E-99 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK77_RS05250 1c67e513b92ba30440699a67c35c9eef 559 PRINTS PR01165 Cytochrome c oxidase subunit I signature 144 156 1.3E-99 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK77_RS05250 1c67e513b92ba30440699a67c35c9eef 559 PRINTS PR01165 Cytochrome c oxidase subunit I signature 255 276 1.3E-99 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK77_RS05250 1c67e513b92ba30440699a67c35c9eef 559 PRINTS PR01165 Cytochrome c oxidase subunit I signature 74 97 1.3E-99 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK77_RS05250 1c67e513b92ba30440699a67c35c9eef 559 PRINTS PR01165 Cytochrome c oxidase subunit I signature 436 457 1.3E-99 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK77_RS05250 1c67e513b92ba30440699a67c35c9eef 559 PRINTS PR01165 Cytochrome c oxidase subunit I signature 176 194 1.3E-99 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK77_RS05250 1c67e513b92ba30440699a67c35c9eef 559 PRINTS PR01165 Cytochrome c oxidase subunit I signature 358 376 1.3E-99 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK77_RS05250 1c67e513b92ba30440699a67c35c9eef 559 PRINTS PR01165 Cytochrome c oxidase subunit I signature 101 125 1.3E-99 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK77_RS05250 1c67e513b92ba30440699a67c35c9eef 559 PRINTS PR01165 Cytochrome c oxidase subunit I signature 386 405 1.3E-99 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK77_RS05250 1c67e513b92ba30440699a67c35c9eef 559 PRINTS PR01165 Cytochrome c oxidase subunit I signature 205 224 1.3E-99 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK77_RS05250 1c67e513b92ba30440699a67c35c9eef 559 PRINTS PR01165 Cytochrome c oxidase subunit I signature 234 255 1.3E-99 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK77_RS05250 1c67e513b92ba30440699a67c35c9eef 559 Gene3D G3DSA:1.20.210.10 21 548 3.9E-190 T 06-07-2017 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK77_RS05250 1c67e513b92ba30440699a67c35c9eef 559 SUPERFAMILY SSF81442 25 535 5.89E-174 T 06-07-2017 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK77_RS05250 1c67e513b92ba30440699a67c35c9eef 559 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 29 532 2.2E-213 T 06-07-2017 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005507|GO:0005886|GO:0006810|GO:0022900|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 CAK77_RS05250 1c67e513b92ba30440699a67c35c9eef 559 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 257 311 - T 06-07-2017 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK77_RS19415 840249fef93ab78e4d87cf9a5d625350 737 Gene3D G3DSA:3.40.50.1820 349 446 5.1E-36 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS19415 840249fef93ab78e4d87cf9a5d625350 737 Gene3D G3DSA:3.40.50.1820 143 274 5.1E-36 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS19415 840249fef93ab78e4d87cf9a5d625350 737 SUPERFAMILY SSF53474 147 271 4.1E-18 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS17435 cdd5cfb1c8a70d6571a2000e9d030357 582 Gene3D G3DSA:2.40.110.10 143 240 3.1E-11 T 06-07-2017 CAK77_RS17435 cdd5cfb1c8a70d6571a2000e9d030357 582 Gene3D G3DSA:1.20.140.10 241 404 3.1E-16 T 06-07-2017 CAK77_RS17435 cdd5cfb1c8a70d6571a2000e9d030357 582 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 255 402 7.6E-12 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS17435 cdd5cfb1c8a70d6571a2000e9d030357 582 SUPERFAMILY SSF47203 254 405 6.6E-18 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS17435 cdd5cfb1c8a70d6571a2000e9d030357 582 SUPERFAMILY SSF56645 23 248 3.93E-24 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK77_RS07465 6ad4929df8c30e3ca0af44e143902fd4 258 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 4 239 9.8E-107 T 06-07-2017 IPR002381 Ribonuclease phosphorolytic, bacterial-type GO:0000049|GO:0004549|GO:0008033 CAK77_RS07465 6ad4929df8c30e3ca0af44e143902fd4 258 SUPERFAMILY SSF54211 3 184 6.58E-45 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAK77_RS07465 6ad4929df8c30e3ca0af44e143902fd4 258 Hamap MF_00564 Ribonuclease PH [rph]. 3 240 46.451 T 06-07-2017 IPR002381 Ribonuclease phosphorolytic, bacterial-type GO:0000049|GO:0004549|GO:0008033 CAK77_RS07465 6ad4929df8c30e3ca0af44e143902fd4 258 SUPERFAMILY SSF55666 156 248 8.9E-20 T 06-07-2017 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CAK77_RS07465 6ad4929df8c30e3ca0af44e143902fd4 258 Pfam PF03725 3' exoribonuclease family, domain 2 161 224 8.1E-9 T 06-07-2017 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CAK77_RS07465 6ad4929df8c30e3ca0af44e143902fd4 258 ProSitePatterns PS01277 Ribonuclease PH signature. 118 131 - T 06-07-2017 IPR018336 Ribonuclease PH, conserved site CAK77_RS07465 6ad4929df8c30e3ca0af44e143902fd4 258 Pfam PF01138 3' exoribonuclease family, domain 1 12 142 1.0E-24 T 06-07-2017 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CAK77_RS07465 6ad4929df8c30e3ca0af44e143902fd4 258 Gene3D G3DSA:3.30.230.70 7 239 1.9E-30 T 06-07-2017 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CAK77_RS23225 65dd71863d53614268a4c68e8b81dee3 114 SUPERFAMILY SSF50475 2 91 1.87E-15 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS23225 65dd71863d53614268a4c68e8b81dee3 114 Gene3D G3DSA:2.30.110.10 1 91 1.5E-19 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS23225 65dd71863d53614268a4c68e8b81dee3 114 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 9 90 7.6E-10 T 06-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAK77_RS23225 65dd71863d53614268a4c68e8b81dee3 114 TIGRFAM TIGR04023 PPOX_MSMEG_5819: PPOX class F420-dependent enzyme, MSMEG_5819/OxyR family 3 91 2.3E-36 T 06-07-2017 IPR024031 PPOX class F420-dependent enzyme, MSMEG_5819/OxyR family CAK77_RS00615 197752aa945463e334b3a9518b057056 1527 SUPERFAMILY SSF56235 18 442 2.51E-146 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAK77_RS00615 197752aa945463e334b3a9518b057056 1527 Pfam PF01645 Conserved region in glutamate synthase 822 1190 2.8E-153 T 06-07-2017 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 CAK77_RS00615 197752aa945463e334b3a9518b057056 1527 Gene3D G3DSA:3.20.20.70 451 810 1.5E-104 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK77_RS00615 197752aa945463e334b3a9518b057056 1527 Gene3D G3DSA:2.160.20.60 1245 1519 1.0E-106 T 06-07-2017 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 CAK77_RS00615 197752aa945463e334b3a9518b057056 1527 SUPERFAMILY SSF51395 455 1225 2.65E-263 T 06-07-2017 CAK77_RS00615 197752aa945463e334b3a9518b057056 1527 Pfam PF01493 GXGXG motif 1272 1459 3.1E-81 T 06-07-2017 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 CAK77_RS00615 197752aa945463e334b3a9518b057056 1527 Pfam PF00310 Glutamine amidotransferases class-II 18 439 3.3E-179 T 06-07-2017 IPR017932 Glutamine amidotransferase type 2 domain CAK77_RS00615 197752aa945463e334b3a9518b057056 1527 Pfam PF04898 Glutamate synthase central domain 466 757 7.0E-115 T 06-07-2017 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 CAK77_RS00615 197752aa945463e334b3a9518b057056 1527 Gene3D G3DSA:3.60.20.10 18 450 4.4E-182 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAK77_RS00615 197752aa945463e334b3a9518b057056 1527 SUPERFAMILY SSF69336 1240 1506 1.57E-93 T 06-07-2017 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 CAK77_RS00615 197752aa945463e334b3a9518b057056 1527 Gene3D G3DSA:3.20.20.70 813 1227 6.8E-179 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK77_RS16030 80347c354a85d854bf8db5e1b84fa584 234 Gene3D G3DSA:3.30.420.10 32 173 7.7E-39 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAK77_RS16030 80347c354a85d854bf8db5e1b84fa584 234 SUPERFAMILY SSF53098 21 216 5.92E-62 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAK77_RS16030 80347c354a85d854bf8db5e1b84fa584 234 Pfam PF01351 Ribonuclease HII 33 212 1.8E-43 T 06-07-2017 IPR024567 Ribonuclease HII/HIII domain CAK77_RS16030 80347c354a85d854bf8db5e1b84fa584 234 Hamap MF_00052_B Ribonuclease HII [rnhB]. 31 212 36.532 T 06-07-2017 IPR022898 Ribonuclease HII GO:0004523 CAK77_RS22660 a7cd5aa906c955c31daccbb341922953 321 Pfam PF08281 Sigma-70, region 4 129 181 1.3E-12 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS22660 a7cd5aa906c955c31daccbb341922953 321 Gene3D G3DSA:1.10.1740.10 10 97 1.0E-26 T 06-07-2017 CAK77_RS22660 a7cd5aa906c955c31daccbb341922953 321 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 35 66 - T 06-07-2017 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS22660 a7cd5aa906c955c31daccbb341922953 321 Gene3D G3DSA:1.10.10.10 125 183 1.9E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS22660 a7cd5aa906c955c31daccbb341922953 321 SUPERFAMILY SSF54427 199 306 2.04E-14 T 06-07-2017 IPR032710 NTF2-like domain CAK77_RS22660 a7cd5aa906c955c31daccbb341922953 321 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 14 183 3.5E-26 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS22660 a7cd5aa906c955c31daccbb341922953 321 SUPERFAMILY SSF88659 98 185 3.18E-12 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS22660 a7cd5aa906c955c31daccbb341922953 321 SUPERFAMILY SSF88946 13 84 1.18E-22 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS22660 a7cd5aa906c955c31daccbb341922953 321 TIGRFAM TIGR02960 SigX5: RNA polymerase sigma-70 factor, TIGR02960 family 8 315 4.9E-123 T 06-07-2017 IPR014305 RNA polymerase sigma-G type, actinobacteria CAK77_RS22660 a7cd5aa906c955c31daccbb341922953 321 Gene3D G3DSA:3.10.450.50 200 317 2.2E-20 T 06-07-2017 IPR032710 NTF2-like domain CAK77_RS22660 a7cd5aa906c955c31daccbb341922953 321 Pfam PF04542 Sigma-70 region 2 15 80 7.5E-20 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS10990 824e4d39c0bd017e140fa1545b0b0dcf 582 SUPERFAMILY SSF90123 7 319 7.06E-31 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAK77_RS10990 824e4d39c0bd017e140fa1545b0b0dcf 582 Pfam PF00664 ABC transporter transmembrane region 19 275 2.3E-6 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAK77_RS10990 824e4d39c0bd017e140fa1545b0b0dcf 582 ProSitePatterns PS00211 ABC transporters family signature. 471 485 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK77_RS10990 824e4d39c0bd017e140fa1545b0b0dcf 582 SMART SM00382 359 545 1.2E-17 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS10990 824e4d39c0bd017e140fa1545b0b0dcf 582 Gene3D G3DSA:1.20.1560.10 11 321 3.7E-25 T 06-07-2017 CAK77_RS10990 824e4d39c0bd017e140fa1545b0b0dcf 582 SUPERFAMILY SSF52540 329 569 4.5E-79 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS10990 824e4d39c0bd017e140fa1545b0b0dcf 582 Gene3D G3DSA:3.40.50.300 332 559 5.0E-74 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS10990 824e4d39c0bd017e140fa1545b0b0dcf 582 Pfam PF00005 ABC transporter 350 499 1.1E-35 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK77_RS11260 6c8273e76b5aca27678ce420498be403 225 SMART SM00849 39 204 3.8E-27 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK77_RS11260 6c8273e76b5aca27678ce420498be403 225 Pfam PF00753 Metallo-beta-lactamase superfamily 36 204 8.0E-14 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK77_RS11260 6c8273e76b5aca27678ce420498be403 225 SUPERFAMILY SSF56281 33 221 9.48E-42 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK77_RS11260 6c8273e76b5aca27678ce420498be403 225 Gene3D G3DSA:3.60.15.10 23 223 3.7E-48 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK77_RS04580 3ef4bd7b9eb0c36cb306b3fa132242cc 378 PRINTS PR00143 Citrate synthase signature 168 183 9.7E-24 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 CAK77_RS04580 3ef4bd7b9eb0c36cb306b3fa132242cc 378 PRINTS PR00143 Citrate synthase signature 243 263 9.7E-24 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 CAK77_RS04580 3ef4bd7b9eb0c36cb306b3fa132242cc 378 PRINTS PR00143 Citrate synthase signature 322 336 9.7E-24 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 CAK77_RS04580 3ef4bd7b9eb0c36cb306b3fa132242cc 378 PRINTS PR00143 Citrate synthase signature 190 218 9.7E-24 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 CAK77_RS04580 3ef4bd7b9eb0c36cb306b3fa132242cc 378 PRINTS PR00143 Citrate synthase signature 302 318 9.7E-24 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 CAK77_RS04580 3ef4bd7b9eb0c36cb306b3fa132242cc 378 Pfam PF00285 Citrate synthase, C-terminal domain 14 64 1.9E-9 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 CAK77_RS04580 3ef4bd7b9eb0c36cb306b3fa132242cc 378 Pfam PF00285 Citrate synthase, C-terminal domain 114 352 3.0E-70 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 CAK77_RS04580 3ef4bd7b9eb0c36cb306b3fa132242cc 378 Gene3D G3DSA:1.10.230.10 230 314 7.6E-22 T 06-07-2017 IPR016143 Citrate synthase-like, small alpha subdomain Reactome: R-HSA-163765|Reactome: R-HSA-75105 CAK77_RS04580 3ef4bd7b9eb0c36cb306b3fa132242cc 378 ProSitePatterns PS00480 Citrate synthase signature. 250 262 - T 06-07-2017 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 CAK77_RS04580 3ef4bd7b9eb0c36cb306b3fa132242cc 378 SUPERFAMILY SSF48256 10 363 7.33E-90 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 CAK77_RS04580 3ef4bd7b9eb0c36cb306b3fa132242cc 378 Gene3D G3DSA:1.10.580.10 20 229 4.5E-42 T 06-07-2017 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 CAK77_RS07755 af7b1ffa5c9778e3aa495124a679baba 247 Pfam PF05423 Mycobacterium membrane protein 163 234 9.5E-8 T 06-07-2017 IPR008693 Transport accessory protein MmpS CAK77_RS00145 27be29971cf345d5d72ea06cb040bd40 142 Gene3D G3DSA:1.10.10.60 18 58 1.1E-6 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS02445 27be29971cf345d5d72ea06cb040bd40 142 Gene3D G3DSA:1.10.10.60 18 58 1.1E-6 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS16485 20e49b6530a2fa4a76005c22869f012b 2557 Pfam PF13193 AMP-binding enzyme C-terminal domain 1938 2009 9.9E-10 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAK77_RS16485 20e49b6530a2fa4a76005c22869f012b 2557 Pfam PF13193 AMP-binding enzyme C-terminal domain 443 514 2.6E-7 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAK77_RS16485 20e49b6530a2fa4a76005c22869f012b 2557 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 923 1082 2.1E-32 T 06-07-2017 IPR010060 Non-ribosomal peptide synthase CAK77_RS16485 20e49b6530a2fa4a76005c22869f012b 2557 Pfam PF00550 Phosphopantetheine attachment site 2036 2099 4.6E-11 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS16485 20e49b6530a2fa4a76005c22869f012b 2557 Pfam PF00550 Phosphopantetheine attachment site 540 601 9.7E-10 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS16485 20e49b6530a2fa4a76005c22869f012b 2557 SUPERFAMILY SSF52777 1269 1510 8.67E-53 T 06-07-2017 CAK77_RS16485 20e49b6530a2fa4a76005c22869f012b 2557 Gene3D G3DSA:1.10.1200.10 542 603 5.7E-24 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS16485 20e49b6530a2fa4a76005c22869f012b 2557 Gene3D G3DSA:1.10.1200.10 2039 2101 7.9E-23 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS16485 20e49b6530a2fa4a76005c22869f012b 2557 SUPERFAMILY SSF52777 798 1059 6.23E-22 T 06-07-2017 CAK77_RS16485 20e49b6530a2fa4a76005c22869f012b 2557 SUPERFAMILY SSF47336 2026 2099 4.19E-18 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS16485 20e49b6530a2fa4a76005c22869f012b 2557 Pfam PF07993 Male sterility protein 2161 2423 2.8E-59 T 06-07-2017 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 CAK77_RS16485 20e49b6530a2fa4a76005c22869f012b 2557 TIGRFAM TIGR01746 Thioester-redct: thioester reductase domain 2159 2556 2.0E-89 T 06-07-2017 IPR010080 Thioester reductase-like domain CAK77_RS16485 20e49b6530a2fa4a76005c22869f012b 2557 SUPERFAMILY SSF52777 614 780 8.56E-24 T 06-07-2017 CAK77_RS16485 20e49b6530a2fa4a76005c22869f012b 2557 Gene3D G3DSA:3.40.50.980 1691 1841 3.3E-37 T 06-07-2017 CAK77_RS16485 20e49b6530a2fa4a76005c22869f012b 2557 Gene3D G3DSA:3.40.50.980 1536 1690 2.6E-46 T 06-07-2017 CAK77_RS16485 20e49b6530a2fa4a76005c22869f012b 2557 Gene3D G3DSA:3.40.50.980 41 206 5.4E-45 T 06-07-2017 CAK77_RS16485 20e49b6530a2fa4a76005c22869f012b 2557 Gene3D G3DSA:3.40.50.980 207 346 3.3E-39 T 06-07-2017 CAK77_RS16485 20e49b6530a2fa4a76005c22869f012b 2557 SMART SM01294 2035 2099 0.0054 T 06-07-2017 CAK77_RS16485 20e49b6530a2fa4a76005c22869f012b 2557 Pfam PF00501 AMP-binding enzyme 46 435 6.8E-86 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK77_RS16485 20e49b6530a2fa4a76005c22869f012b 2557 Pfam PF00501 AMP-binding enzyme 1543 1930 8.3E-83 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK77_RS16485 20e49b6530a2fa4a76005c22869f012b 2557 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2058 2073 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site CAK77_RS16485 20e49b6530a2fa4a76005c22869f012b 2557 ProSitePatterns PS00455 Putative AMP-binding domain signature. 185 196 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK77_RS16485 20e49b6530a2fa4a76005c22869f012b 2557 SUPERFAMILY SSF51735 2159 2462 2.98E-30 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS16485 20e49b6530a2fa4a76005c22869f012b 2557 SUPERFAMILY SSF56801 5 551 1.16E-142 T 06-07-2017 CAK77_RS16485 20e49b6530a2fa4a76005c22869f012b 2557 Gene3D G3DSA:3.40.50.720 2158 2461 1.2E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS16485 20e49b6530a2fa4a76005c22869f012b 2557 SUPERFAMILY SSF56801 1502 2047 4.58E-142 T 06-07-2017 CAK77_RS16485 20e49b6530a2fa4a76005c22869f012b 2557 Pfam PF00668 Condensation domain 638 906 2.9E-18 T 06-07-2017 IPR001242 Condensation domain CAK77_RS16485 20e49b6530a2fa4a76005c22869f012b 2557 Pfam PF00668 Condensation domain 1089 1379 1.6E-47 T 06-07-2017 IPR001242 Condensation domain CAK77_RS16485 20e49b6530a2fa4a76005c22869f012b 2557 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1564 1954 7.8E-125 T 06-07-2017 IPR010071 Amino acid adenylation domain CAK77_RS16485 20e49b6530a2fa4a76005c22869f012b 2557 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 67 459 7.1E-127 T 06-07-2017 IPR010071 Amino acid adenylation domain CAK77_RS16485 20e49b6530a2fa4a76005c22869f012b 2557 SMART SM00823 Phosphopantetheine attachment site 2034 2103 2.6E-4 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAK77_RS16485 20e49b6530a2fa4a76005c22869f012b 2557 SMART SM00823 Phosphopantetheine attachment site 538 606 0.042 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAK77_RS16485 20e49b6530a2fa4a76005c22869f012b 2557 Gene3D G3DSA:3.30.300.30 1925 2038 5.1E-37 T 06-07-2017 CAK77_RS16485 20e49b6530a2fa4a76005c22869f012b 2557 Gene3D G3DSA:3.30.300.30 430 541 5.3E-32 T 06-07-2017 CAK77_RS16485 20e49b6530a2fa4a76005c22869f012b 2557 SUPERFAMILY SSF52777 1088 1284 5.34E-39 T 06-07-2017 CAK77_RS16485 20e49b6530a2fa4a76005c22869f012b 2557 ProSitePatterns PS00012 Phosphopantetheine attachment site. 562 577 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site CAK77_RS16485 20e49b6530a2fa4a76005c22869f012b 2557 SUPERFAMILY SSF47336 531 602 4.45E-16 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS16485 20e49b6530a2fa4a76005c22869f012b 2557 Gene3D G3DSA:2.30.38.10 1842 1920 2.5E-20 T 06-07-2017 CAK77_RS16485 20e49b6530a2fa4a76005c22869f012b 2557 Gene3D G3DSA:2.30.38.10 347 425 7.0E-23 T 06-07-2017 CAK77_RS17725 a9e696a8b1fe4ecc99ca6d4a9907a621 84 Pfam PF02467 Transcription factor WhiB 3 71 7.1E-27 T 06-07-2017 IPR003482 Transcription factor WhiB CAK77_RS17725 a9e696a8b1fe4ecc99ca6d4a9907a621 84 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 76 18.796 T 06-07-2017 IPR003482 Transcription factor WhiB CAK77_RS18625 1cf965baa2008a5bb851c97a4eed7e9c 344 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 5 312 7.0E-88 T 06-07-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CAK77_RS18625 1cf965baa2008a5bb851c97a4eed7e9c 344 SUPERFAMILY SSF53067 104 312 1.53E-35 T 06-07-2017 CAK77_RS18625 1cf965baa2008a5bb851c97a4eed7e9c 344 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 2 338 59.697 T 06-07-2017 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CAK77_RS18625 1cf965baa2008a5bb851c97a4eed7e9c 344 Pfam PF00814 Glycoprotease family 29 312 1.1E-87 T 06-07-2017 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CAK77_RS18625 1cf965baa2008a5bb851c97a4eed7e9c 344 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 4 318 4.7E-114 T 06-07-2017 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CAK77_RS18625 1cf965baa2008a5bb851c97a4eed7e9c 344 SUPERFAMILY SSF53067 4 125 1.49E-23 T 06-07-2017 CAK77_RS18625 1cf965baa2008a5bb851c97a4eed7e9c 344 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 5 18 1.7E-51 T 06-07-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CAK77_RS18625 1cf965baa2008a5bb851c97a4eed7e9c 344 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 100 119 1.7E-51 T 06-07-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CAK77_RS18625 1cf965baa2008a5bb851c97a4eed7e9c 344 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 157 178 1.7E-51 T 06-07-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CAK77_RS18625 1cf965baa2008a5bb851c97a4eed7e9c 344 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 133 145 1.7E-51 T 06-07-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CAK77_RS18625 1cf965baa2008a5bb851c97a4eed7e9c 344 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 79 99 1.7E-51 T 06-07-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CAK77_RS18625 1cf965baa2008a5bb851c97a4eed7e9c 344 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 269 278 1.7E-51 T 06-07-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CAK77_RS18625 1cf965baa2008a5bb851c97a4eed7e9c 344 Gene3D G3DSA:3.30.420.40 3 161 2.0E-36 T 06-07-2017 CAK77_RS18625 1cf965baa2008a5bb851c97a4eed7e9c 344 ProSitePatterns PS01016 Glycoprotease family signature. 99 119 - T 06-07-2017 IPR017860 Peptidase M22, conserved site KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618|Reactome: R-HSA-6782315 CAK77_RS06730 963c4f1d9201e998c33021218d32f7da 596 Gene3D G3DSA:2.30.38.10 391 445 6.1E-6 T 06-07-2017 CAK77_RS06730 963c4f1d9201e998c33021218d32f7da 596 Pfam PF13193 AMP-binding enzyme C-terminal domain 472 548 1.5E-11 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAK77_RS06730 963c4f1d9201e998c33021218d32f7da 596 SUPERFAMILY SSF56801 50 560 1.31E-101 T 06-07-2017 CAK77_RS06730 963c4f1d9201e998c33021218d32f7da 596 Pfam PF00501 AMP-binding enzyme 56 463 1.4E-65 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK77_RS06730 963c4f1d9201e998c33021218d32f7da 596 Gene3D G3DSA:3.40.50.980 209 353 6.1E-23 T 06-07-2017 CAK77_RS06730 963c4f1d9201e998c33021218d32f7da 596 Gene3D G3DSA:3.40.50.980 52 208 1.2E-36 T 06-07-2017 CAK77_RS06730 963c4f1d9201e998c33021218d32f7da 596 Gene3D G3DSA:3.30.300.30 461 558 1.8E-14 T 06-07-2017 CAK77_RS06730 963c4f1d9201e998c33021218d32f7da 596 ProSitePatterns PS00455 Putative AMP-binding domain signature. 203 214 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK77_RS07455 64decc820da93b160d0bd81e8cf48cf6 282 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 180 190 - T 06-07-2017 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK77_RS07455 64decc820da93b160d0bd81e8cf48cf6 282 SUPERFAMILY SSF53681 5 108 5.56E-31 T 06-07-2017 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK77_RS07455 64decc820da93b160d0bd81e8cf48cf6 282 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 70 78 - T 06-07-2017 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK77_RS07455 64decc820da93b160d0bd81e8cf48cf6 282 Hamap MF_00258 Glutamate racemase [murI]. 4 261 36.522 T 06-07-2017 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK77_RS07455 64decc820da93b160d0bd81e8cf48cf6 282 SUPERFAMILY SSF53681 110 265 6.7E-40 T 06-07-2017 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK77_RS07455 64decc820da93b160d0bd81e8cf48cf6 282 TIGRFAM TIGR00067 glut_race: glutamate racemase 6 257 2.3E-64 T 06-07-2017 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK77_RS07455 64decc820da93b160d0bd81e8cf48cf6 282 Gene3D G3DSA:3.40.50.1860 2 173 2.4E-51 T 06-07-2017 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK77_RS07455 64decc820da93b160d0bd81e8cf48cf6 282 Pfam PF01177 Asp/Glu/Hydantoin racemase 6 215 3.4E-31 T 06-07-2017 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK77_RS03540 f927d108523f18533381c6bf75a2ba37 266 Gene3D G3DSA:3.40.50.1820 28 261 1.2E-28 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS03540 f927d108523f18533381c6bf75a2ba37 266 SUPERFAMILY SSF53474 38 261 9.89E-24 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS07780 9a88ba0bc31dbca6207c25947b1ecadc 625 Gene3D G3DSA:2.40.30.10 316 419 2.6E-8 T 06-07-2017 CAK77_RS07780 9a88ba0bc31dbca6207c25947b1ecadc 625 SUPERFAMILY SSF52540 8 213 2.02E-51 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS07780 9a88ba0bc31dbca6207c25947b1ecadc 625 TIGRFAM TIGR02034 CysN: sulfate adenylyltransferase, large subunit 13 417 9.4E-146 T 06-07-2017 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 CAK77_RS07780 9a88ba0bc31dbca6207c25947b1ecadc 625 SUPERFAMILY SSF50465 316 418 1.53E-26 T 06-07-2017 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal CAK77_RS07780 9a88ba0bc31dbca6207c25947b1ecadc 625 SUPERFAMILY SSF52540 447 622 1.64E-34 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS07780 9a88ba0bc31dbca6207c25947b1ecadc 625 SUPERFAMILY SSF50447 222 306 2.59E-13 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain CAK77_RS07780 9a88ba0bc31dbca6207c25947b1ecadc 625 Gene3D G3DSA:3.40.50.300 8 214 4.7E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS07780 9a88ba0bc31dbca6207c25947b1ecadc 625 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 451 625 36.818 T 06-07-2017 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 CAK77_RS07780 9a88ba0bc31dbca6207c25947b1ecadc 625 Pfam PF00009 Elongation factor Tu GTP binding domain 12 207 1.3E-38 T 06-07-2017 CAK77_RS07780 9a88ba0bc31dbca6207c25947b1ecadc 625 Gene3D G3DSA:2.40.30.10 222 305 3.1E-12 T 06-07-2017 CAK77_RS07780 9a88ba0bc31dbca6207c25947b1ecadc 625 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 435 621 1.2E-66 T 06-07-2017 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 CAK77_RS07780 9a88ba0bc31dbca6207c25947b1ecadc 625 Gene3D G3DSA:3.40.50.300 431 623 7.4E-77 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS07780 9a88ba0bc31dbca6207c25947b1ecadc 625 Pfam PF01583 Adenylylsulphate kinase 452 607 2.7E-64 T 06-07-2017 CAK77_RS07780 9a88ba0bc31dbca6207c25947b1ecadc 625 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 61 76 - T 06-07-2017 IPR031157 Tr-type G domain, conserved site CAK77_RS07780 9a88ba0bc31dbca6207c25947b1ecadc 625 PRINTS PR00315 GTP-binding elongation factor signature 88 98 2.6E-11 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAK77_RS07780 9a88ba0bc31dbca6207c25947b1ecadc 625 PRINTS PR00315 GTP-binding elongation factor signature 104 115 2.6E-11 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAK77_RS07780 9a88ba0bc31dbca6207c25947b1ecadc 625 PRINTS PR00315 GTP-binding elongation factor signature 14 27 2.6E-11 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAK77_RS07780 9a88ba0bc31dbca6207c25947b1ecadc 625 PRINTS PR00315 GTP-binding elongation factor signature 68 76 2.6E-11 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAK77_RS07780 9a88ba0bc31dbca6207c25947b1ecadc 625 PRINTS PR00315 GTP-binding elongation factor signature 141 150 2.6E-11 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAK77_RS14160 96161bf1d108c852367e6cc00632ca50 375 SUPERFAMILY SSF53756 2 364 4.71E-74 T 06-07-2017 CAK77_RS14160 96161bf1d108c852367e6cc00632ca50 375 Pfam PF13439 Glycosyltransferase Family 4 14 172 2.4E-24 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 CAK77_RS14160 96161bf1d108c852367e6cc00632ca50 375 Gene3D G3DSA:3.40.50.2000 166 341 2.3E-24 T 06-07-2017 CAK77_RS14160 96161bf1d108c852367e6cc00632ca50 375 Pfam PF13692 Glycosyl transferases group 1 189 328 5.1E-32 T 06-07-2017 CAK77_RS03005 b9c1bb9ca05de3b387b5bc77d56574f4 225 SUPERFAMILY SSF46689 43 104 9.48E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS03005 b9c1bb9ca05de3b387b5bc77d56574f4 225 Pfam PF00440 Bacterial regulatory proteins, tetR family 49 93 3.3E-15 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS03005 b9c1bb9ca05de3b387b5bc77d56574f4 225 Gene3D G3DSA:1.10.357.10 44 223 2.1E-33 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS03005 b9c1bb9ca05de3b387b5bc77d56574f4 225 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 49 62 3.2E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS03005 b9c1bb9ca05de3b387b5bc77d56574f4 225 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 70 93 3.2E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS22875 fa6b2588dccdde72f4f9ef214de5ca68 379 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 19 308 1.6E-47 T 06-07-2017 IPR005693 Virulence factor Mce protein CAK77_RS22875 fa6b2588dccdde72f4f9ef214de5ca68 379 Pfam PF02470 MlaD protein 44 119 9.6E-13 T 06-07-2017 IPR003399 Mce/MlaD CAK77_RS13090 5da80e6bb4b0f773bea4946d9e70a3af 446 PRINTS PR00083 Histidinol dehydrogenase signature 143 169 7.2E-85 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CAK77_RS13090 5da80e6bb4b0f773bea4946d9e70a3af 446 PRINTS PR00083 Histidinol dehydrogenase signature 244 265 7.2E-85 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CAK77_RS13090 5da80e6bb4b0f773bea4946d9e70a3af 446 PRINTS PR00083 Histidinol dehydrogenase signature 215 240 7.2E-85 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CAK77_RS13090 5da80e6bb4b0f773bea4946d9e70a3af 446 PRINTS PR00083 Histidinol dehydrogenase signature 336 361 7.2E-85 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CAK77_RS13090 5da80e6bb4b0f773bea4946d9e70a3af 446 PRINTS PR00083 Histidinol dehydrogenase signature 377 395 7.2E-85 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CAK77_RS13090 5da80e6bb4b0f773bea4946d9e70a3af 446 PRINTS PR00083 Histidinol dehydrogenase signature 266 285 7.2E-85 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CAK77_RS13090 5da80e6bb4b0f773bea4946d9e70a3af 446 PRINTS PR00083 Histidinol dehydrogenase signature 42 66 7.2E-85 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CAK77_RS13090 5da80e6bb4b0f773bea4946d9e70a3af 446 PRINTS PR00083 Histidinol dehydrogenase signature 180 206 7.2E-85 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CAK77_RS13090 5da80e6bb4b0f773bea4946d9e70a3af 446 SUPERFAMILY SSF53720 34 443 1.9E-69 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAK77_RS13090 5da80e6bb4b0f773bea4946d9e70a3af 446 Pfam PF00815 Histidinol dehydrogenase 30 443 2.7E-153 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CAK77_RS13090 5da80e6bb4b0f773bea4946d9e70a3af 446 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 14 443 38.344 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CAK77_RS13090 5da80e6bb4b0f773bea4946d9e70a3af 446 Gene3D G3DSA:3.40.50.1980 36 254 5.2E-74 T 06-07-2017 CAK77_RS13090 5da80e6bb4b0f773bea4946d9e70a3af 446 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 42 442 1.8E-137 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CAK77_RS13090 5da80e6bb4b0f773bea4946d9e70a3af 446 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 244 276 - T 06-07-2017 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 CAK77_RS13090 5da80e6bb4b0f773bea4946d9e70a3af 446 PIRSF PIRSF000099 8 446 1.3E-148 T 06-07-2017 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CAK77_RS04540 bb4076f3f05d187217f724ce86518c52 140 Gene3D G3DSA:3.30.300.20 45 138 1.1E-34 T 06-07-2017 IPR015946 K homology domain-like, alpha/beta CAK77_RS04540 bb4076f3f05d187217f724ce86518c52 140 TIGRFAM TIGR03561 organ_hyd_perox: peroxiredoxin, Ohr subfamily 4 137 1.4E-53 T 06-07-2017 IPR019953 Organic hydroperoxide resistance protein famiy GO:0006979 CAK77_RS04540 bb4076f3f05d187217f724ce86518c52 140 Gene3D G3DSA:2.20.25.10 2 44 1.5E-18 T 06-07-2017 CAK77_RS04540 bb4076f3f05d187217f724ce86518c52 140 SUPERFAMILY SSF82784 3 137 6.67E-39 T 06-07-2017 IPR003718 OsmC/Ohr family CAK77_RS04540 bb4076f3f05d187217f724ce86518c52 140 Pfam PF02566 OsmC-like protein 39 135 5.2E-17 T 06-07-2017 IPR003718 OsmC/Ohr family CAK77_RS12065 e7540ca709ee0b541ed3c4f3aebf0dbd 471 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 21 447 1.6E-163 T 06-07-2017 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 CAK77_RS12065 e7540ca709ee0b541ed3c4f3aebf0dbd 471 Pfam PF00296 Luciferase-like monooxygenase 42 399 1.0E-54 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS12065 e7540ca709ee0b541ed3c4f3aebf0dbd 471 Gene3D G3DSA:3.20.20.30 18 329 9.1E-131 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS12065 e7540ca709ee0b541ed3c4f3aebf0dbd 471 Gene3D G3DSA:3.20.20.30 365 453 9.1E-131 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS12065 e7540ca709ee0b541ed3c4f3aebf0dbd 471 SUPERFAMILY SSF51679 19 453 2.49E-122 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS12065 e7540ca709ee0b541ed3c4f3aebf0dbd 471 PIRSF PIRSF000337 16 461 2.1E-141 T 06-07-2017 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 CAK77_RS10100 2ada5efae4c2c651de194e4ce3e5d2c5 381 Gene3D G3DSA:2.40.110.10 124 220 3.3E-39 T 06-07-2017 CAK77_RS10100 2ada5efae4c2c651de194e4ce3e5d2c5 381 Gene3D G3DSA:1.10.540.10 5 123 3.3E-35 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS10100 2ada5efae4c2c651de194e4ce3e5d2c5 381 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 125 220 1.3E-26 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAK77_RS10100 2ada5efae4c2c651de194e4ce3e5d2c5 381 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 340 359 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CAK77_RS10100 2ada5efae4c2c651de194e4ce3e5d2c5 381 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 12 121 2.8E-31 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS10100 2ada5efae4c2c651de194e4ce3e5d2c5 381 Gene3D G3DSA:1.20.140.10 221 381 2.2E-54 T 06-07-2017 CAK77_RS10100 2ada5efae4c2c651de194e4ce3e5d2c5 381 SUPERFAMILY SSF47203 232 381 3.06E-49 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS10100 2ada5efae4c2c651de194e4ce3e5d2c5 381 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 233 381 9.5E-42 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS10100 2ada5efae4c2c651de194e4ce3e5d2c5 381 SUPERFAMILY SSF56645 6 245 5.5E-83 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK77_RS10100 2ada5efae4c2c651de194e4ce3e5d2c5 381 PIRSF PIRSF016578 5 381 2.3E-14 T 06-07-2017 CAK77_RS00630 4e22d0fa2d688f11cc0785a1b65768d5 255 Hamap MF_01974 Methionine aminopeptidase [map]. 2 254 33.111 T 06-07-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 CAK77_RS00630 4e22d0fa2d688f11cc0785a1b65768d5 255 Gene3D G3DSA:3.90.230.10 3 252 3.0E-69 T 06-07-2017 IPR000994 Peptidase M24, structural domain CAK77_RS00630 4e22d0fa2d688f11cc0785a1b65768d5 255 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 2 252 9.9E-71 T 06-07-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 CAK77_RS00630 4e22d0fa2d688f11cc0785a1b65768d5 255 PRINTS PR00599 Methionine aminopeptidase-1 signature 196 208 1.8E-17 T 06-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase CAK77_RS00630 4e22d0fa2d688f11cc0785a1b65768d5 255 PRINTS PR00599 Methionine aminopeptidase-1 signature 165 177 1.8E-17 T 06-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase CAK77_RS00630 4e22d0fa2d688f11cc0785a1b65768d5 255 PRINTS PR00599 Methionine aminopeptidase-1 signature 95 111 1.8E-17 T 06-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase CAK77_RS00630 4e22d0fa2d688f11cc0785a1b65768d5 255 PRINTS PR00599 Methionine aminopeptidase-1 signature 73 86 1.8E-17 T 06-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase CAK77_RS00630 4e22d0fa2d688f11cc0785a1b65768d5 255 SUPERFAMILY SSF55920 2 252 3.14E-70 T 06-07-2017 IPR000994 Peptidase M24, structural domain CAK77_RS00630 4e22d0fa2d688f11cc0785a1b65768d5 255 Pfam PF00557 Metallopeptidase family M24 13 245 3.3E-42 T 06-07-2017 IPR000994 Peptidase M24, structural domain CAK77_RS06755 755c07fe70d0cf34e6544c4c2de58747 163 Gene3D G3DSA:2.30.110.10 23 118 4.5E-15 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS06755 755c07fe70d0cf34e6544c4c2de58747 163 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 24 97 3.2E-6 T 06-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAK77_RS06755 755c07fe70d0cf34e6544c4c2de58747 163 SUPERFAMILY SSF50475 24 130 1.45E-16 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS08145 240022eb9aa573cfe59ae087e6ed7758 635 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 510 590 6.6E-8 T 06-07-2017 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II CAK77_RS08145 240022eb9aa573cfe59ae087e6ed7758 635 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 259 470 7.8E-57 T 06-07-2017 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 CAK77_RS08145 240022eb9aa573cfe59ae087e6ed7758 635 Gene3D G3DSA:3.40.920.10 13 213 6.4E-26 T 06-07-2017 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CAK77_RS08145 240022eb9aa573cfe59ae087e6ed7758 635 Gene3D G3DSA:3.40.50.920 509 611 1.7E-11 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CAK77_RS08145 240022eb9aa573cfe59ae087e6ed7758 635 Gene3D G3DSA:3.40.50.970 226 426 2.4E-73 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK77_RS08145 240022eb9aa573cfe59ae087e6ed7758 635 SUPERFAMILY SSF53323 15 220 2.88E-18 T 06-07-2017 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 CAK77_RS08145 240022eb9aa573cfe59ae087e6ed7758 635 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 21 209 3.5E-28 T 06-07-2017 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CAK77_RS08145 240022eb9aa573cfe59ae087e6ed7758 635 TIGRFAM TIGR03710 OAFO_sf: 2-oxoacid:acceptor oxidoreductase, alpha subunit 13 603 1.1E-200 T 06-07-2017 IPR022367 2-oxoacid:acceptor oxidoreductase, alpha subunit KEGG: 00020+1.2.7.3|KEGG: 00720+1.2.7.3|MetaCyc: PWY-5392|MetaCyc: PWY-6969 CAK77_RS08145 240022eb9aa573cfe59ae087e6ed7758 635 SUPERFAMILY SSF52922 509 611 3.77E-16 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CAK77_RS08145 240022eb9aa573cfe59ae087e6ed7758 635 SUPERFAMILY SSF52518 233 489 2.65E-60 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK77_RS21395 44c34ab59a3b5076562df2db70de5daf 365 Pfam PF03663 Glycosyl hydrolase family 76 28 321 1.2E-28 T 06-07-2017 IPR005198 Glycoside hydrolase, family 76 KEGG: 00052+3.2.1.10|KEGG: 00500+3.2.1.10 CAK77_RS21395 44c34ab59a3b5076562df2db70de5daf 365 PIRSF PIRSF021505 1 365 7.6E-66 T 06-07-2017 IPR014512 Predicted O-glycosyl hydrolase CAK77_RS21395 44c34ab59a3b5076562df2db70de5daf 365 SUPERFAMILY SSF48208 33 296 4.49E-23 T 06-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 CAK77_RS21395 44c34ab59a3b5076562df2db70de5daf 365 Gene3D G3DSA:1.50.10.10 36 250 7.7E-14 T 06-07-2017 IPR012341 Six-hairpin glycosidase GO:0003824 CAK77_RS04170 f4a7f26735b69f097cc542341007a5d5 474 SUPERFAMILY SSF53383 106 468 2.96E-78 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK77_RS04170 f4a7f26735b69f097cc542341007a5d5 474 Gene3D G3DSA:3.90.1150.10 366 464 3.9E-11 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK77_RS04170 f4a7f26735b69f097cc542341007a5d5 474 Pfam PF00155 Aminotransferase class I and II 144 461 5.0E-25 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAK77_RS04170 f4a7f26735b69f097cc542341007a5d5 474 SMART SM00345 1 58 1.2E-7 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK77_RS04170 f4a7f26735b69f097cc542341007a5d5 474 Gene3D G3DSA:1.10.10.10 1 62 6.1E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS04170 f4a7f26735b69f097cc542341007a5d5 474 Gene3D G3DSA:3.40.640.10 142 355 5.2E-53 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK77_RS04170 f4a7f26735b69f097cc542341007a5d5 474 Pfam PF00392 Bacterial regulatory proteins, gntR family 1 57 8.4E-10 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK77_RS04170 f4a7f26735b69f097cc542341007a5d5 474 SUPERFAMILY SSF46785 2 60 5.86E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS04130 1e83349a04f1ef2dc4b4f2202500af62 428 SUPERFAMILY SSF103473 10 419 9.16E-75 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK77_RS04130 1e83349a04f1ef2dc4b4f2202500af62 428 Gene3D G3DSA:1.20.1250.20 28 197 1.1E-27 T 06-07-2017 CAK77_RS04130 1e83349a04f1ef2dc4b4f2202500af62 428 Gene3D G3DSA:1.20.1250.20 230 415 1.0E-25 T 06-07-2017 CAK77_RS04130 1e83349a04f1ef2dc4b4f2202500af62 428 Pfam PF07690 Major Facilitator Superfamily 33 266 1.5E-30 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK77_RS09895 5fafede870f5a9a2118921e12a4ff6e7 419 Pfam PF07690 Major Facilitator Superfamily 29 252 2.5E-25 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK77_RS09895 5fafede870f5a9a2118921e12a4ff6e7 419 ProSitePatterns PS00216 Sugar transport proteins signature 1. 79 96 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CAK77_RS09895 5fafede870f5a9a2118921e12a4ff6e7 419 Gene3D G3DSA:1.20.1250.20 226 415 9.9E-20 T 06-07-2017 CAK77_RS09895 5fafede870f5a9a2118921e12a4ff6e7 419 Gene3D G3DSA:1.20.1250.20 27 202 9.9E-24 T 06-07-2017 CAK77_RS09895 5fafede870f5a9a2118921e12a4ff6e7 419 SUPERFAMILY SSF103473 8 403 5.1E-57 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK77_RS18510 05f7f1ca106acc29b676c174d0a79d9f 526 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 9 526 53.207 T 06-07-2017 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 CAK77_RS18510 05f7f1ca106acc29b676c174d0a79d9f 526 SUPERFAMILY SSF54810 405 526 2.48E-47 T 06-07-2017 CAK77_RS18510 05f7f1ca106acc29b676c174d0a79d9f 526 PRINTS PR00097 Anthranilate synthase component II signature 56 65 1.5E-6 T 06-07-2017 CAK77_RS18510 05f7f1ca106acc29b676c174d0a79d9f 526 PRINTS PR00097 Anthranilate synthase component II signature 170 183 1.5E-6 T 06-07-2017 CAK77_RS18510 05f7f1ca106acc29b676c174d0a79d9f 526 PRINTS PR00097 Anthranilate synthase component II signature 83 94 1.5E-6 T 06-07-2017 CAK77_RS18510 05f7f1ca106acc29b676c174d0a79d9f 526 SUPERFAMILY SSF52317 11 201 1.34E-52 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAK77_RS18510 05f7f1ca106acc29b676c174d0a79d9f 526 Gene3D G3DSA:3.30.300.10 401 526 1.4E-49 T 06-07-2017 CAK77_RS18510 05f7f1ca106acc29b676c174d0a79d9f 526 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 83 99 2.7E-5 T 06-07-2017 CAK77_RS18510 05f7f1ca106acc29b676c174d0a79d9f 526 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 53 67 2.7E-5 T 06-07-2017 CAK77_RS18510 05f7f1ca106acc29b676c174d0a79d9f 526 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 12 26 2.7E-5 T 06-07-2017 CAK77_RS18510 05f7f1ca106acc29b676c174d0a79d9f 526 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 12 196 9.3E-75 T 06-07-2017 IPR004739 GMP synthase, N-terminal GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CAK77_RS18510 05f7f1ca106acc29b676c174d0a79d9f 526 PRINTS PR00096 Glutamine amidotransferase superfamily signature 83 94 1.6E-8 T 06-07-2017 CAK77_RS18510 05f7f1ca106acc29b676c174d0a79d9f 526 PRINTS PR00096 Glutamine amidotransferase superfamily signature 56 65 1.6E-8 T 06-07-2017 CAK77_RS18510 05f7f1ca106acc29b676c174d0a79d9f 526 PRINTS PR00096 Glutamine amidotransferase superfamily signature 170 183 1.6E-8 T 06-07-2017 CAK77_RS18510 05f7f1ca106acc29b676c174d0a79d9f 526 Pfam PF00958 GMP synthase C terminal domain 433 525 1.3E-38 T 06-07-2017 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CAK77_RS18510 05f7f1ca106acc29b676c174d0a79d9f 526 Pfam PF00117 Glutamine amidotransferase class-I 14 192 2.3E-39 T 06-07-2017 IPR017926 Glutamine amidotransferase CAK77_RS18510 05f7f1ca106acc29b676c174d0a79d9f 526 Gene3D G3DSA:3.40.50.620 216 398 6.1E-53 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS18510 05f7f1ca106acc29b676c174d0a79d9f 526 SUPERFAMILY SSF52402 186 446 2.87E-50 T 06-07-2017 CAK77_RS18510 05f7f1ca106acc29b676c174d0a79d9f 526 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 206 526 3.7E-142 T 06-07-2017 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CAK77_RS18510 05f7f1ca106acc29b676c174d0a79d9f 526 Gene3D G3DSA:3.40.50.880 5 215 3.7E-58 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAK77_RS08140 a7579ffdc9d7e67db07a335815a16505 778 SUPERFAMILY SSF53706 68 649 3.66E-146 T 06-07-2017 CAK77_RS08140 a7579ffdc9d7e67db07a335815a16505 778 Gene3D G3DSA:3.40.50.740 412 645 1.9E-55 T 06-07-2017 CAK77_RS08140 a7579ffdc9d7e67db07a335815a16505 778 Gene3D G3DSA:3.40.50.740 131 204 1.9E-55 T 06-07-2017 CAK77_RS08140 a7579ffdc9d7e67db07a335815a16505 778 PIRSF PIRSF000144 16 778 0.0 T 06-07-2017 IPR010046 Oxidoreductase alpha (molybdopterin) subunit GO:0008863|GO:0030151|GO:0051539 CAK77_RS08140 a7579ffdc9d7e67db07a335815a16505 778 Pfam PF01568 Molydopterin dinucleotide binding domain 659 769 6.2E-8 T 06-07-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CAK77_RS08140 a7579ffdc9d7e67db07a335815a16505 778 Gene3D G3DSA:3.40.228.10 205 411 5.2E-57 T 06-07-2017 CAK77_RS08140 a7579ffdc9d7e67db07a335815a16505 778 Pfam PF00384 Molybdopterin oxidoreductase 131 509 1.2E-28 T 06-07-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS08140 a7579ffdc9d7e67db07a335815a16505 778 Gene3D G3DSA:2.40.40.20 648 771 3.6E-8 T 06-07-2017 CAK77_RS08140 a7579ffdc9d7e67db07a335815a16505 778 SUPERFAMILY SSF50692 653 776 3.39E-14 T 06-07-2017 IPR009010 Aspartate decarboxylase-like domain CAK77_RS08140 a7579ffdc9d7e67db07a335815a16505 778 TIGRFAM TIGR01701 Fdhalpha-like: oxidoreductase alpha (molybdopterin) subunit 34 776 0.0 T 06-07-2017 IPR010046 Oxidoreductase alpha (molybdopterin) subunit GO:0008863|GO:0030151|GO:0051539 CAK77_RS21090 cb86243469d687ba4a49a219e2c689d1 484 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 257 264 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CAK77_RS21090 cb86243469d687ba4a49a219e2c689d1 484 Gene3D G3DSA:3.40.605.10 12 271 1.4E-88 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAK77_RS21090 cb86243469d687ba4a49a219e2c689d1 484 Pfam PF00171 Aldehyde dehydrogenase family 25 480 1.5E-155 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAK77_RS21090 cb86243469d687ba4a49a219e2c689d1 484 Gene3D G3DSA:3.40.309.10 272 456 2.4E-62 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAK77_RS21090 cb86243469d687ba4a49a219e2c689d1 484 SUPERFAMILY SSF53720 11 483 5.76E-154 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAK77_RS19520 9a9acffbc7fad1e2d251088a230b084f 901 Gene3D G3DSA:3.40.50.300 58 151 4.0E-9 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS19520 9a9acffbc7fad1e2d251088a230b084f 901 SUPERFAMILY SSF52540 41 233 1.92E-13 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS19520 9a9acffbc7fad1e2d251088a230b084f 901 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 851 867 2.2E-8 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK77_RS19520 9a9acffbc7fad1e2d251088a230b084f 901 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 837 851 2.2E-8 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK77_RS19520 9a9acffbc7fad1e2d251088a230b084f 901 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 867 879 2.2E-8 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK77_RS19520 9a9acffbc7fad1e2d251088a230b084f 901 Gene3D G3DSA:1.10.10.10 836 890 1.7E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS19520 9a9acffbc7fad1e2d251088a230b084f 901 SUPERFAMILY SSF46894 829 889 2.86E-14 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAK77_RS19520 9a9acffbc7fad1e2d251088a230b084f 901 Pfam PF00196 Bacterial regulatory proteins, luxR family 837 888 2.7E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK77_RS19520 9a9acffbc7fad1e2d251088a230b084f 901 SUPERFAMILY SSF48452 594 730 1.11E-6 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK77_RS19520 9a9acffbc7fad1e2d251088a230b084f 901 Pfam PF13401 AAA domain 60 151 5.7E-7 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS19520 9a9acffbc7fad1e2d251088a230b084f 901 SMART SM00421 834 891 2.8E-15 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK77_RS19520 9a9acffbc7fad1e2d251088a230b084f 901 Gene3D G3DSA:1.25.40.10 578 729 3.8E-7 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK77_RS19520 9a9acffbc7fad1e2d251088a230b084f 901 SMART SM00382 57 188 0.001 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS22120 4802cea4d48944dd552c11042fd9904a 592 Pfam PF00069 Protein kinase domain 28 277 1.4E-48 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CAK77_RS22120 4802cea4d48944dd552c11042fd9904a 592 Gene3D G3DSA:1.10.510.10 95 295 3.3E-45 T 06-07-2017 CAK77_RS22120 4802cea4d48944dd552c11042fd9904a 592 Gene3D G3DSA:3.30.200.20 23 94 2.4E-22 T 06-07-2017 CAK77_RS22120 4802cea4d48944dd552c11042fd9904a 592 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 147 159 - T 06-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CAK77_RS22120 4802cea4d48944dd552c11042fd9904a 592 SUPERFAMILY SSF56112 25 313 4.72E-69 T 06-07-2017 IPR011009 Protein kinase-like domain CAK77_RS22120 4802cea4d48944dd552c11042fd9904a 592 SMART SM00220 28 290 1.5E-64 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CAK77_RS14730 fbc5c025a739dcab1a3472e7d7a02628 1187 SMART SM00823 Phosphopantetheine attachment site 662 734 0.0015 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAK77_RS14730 fbc5c025a739dcab1a3472e7d7a02628 1187 TIGRFAM TIGR01746 Thioester-redct: thioester reductase domain 785 1186 3.1E-85 T 06-07-2017 IPR010080 Thioester reductase-like domain CAK77_RS14730 fbc5c025a739dcab1a3472e7d7a02628 1187 Gene3D G3DSA:1.10.1200.10 655 734 7.3E-9 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS14730 fbc5c025a739dcab1a3472e7d7a02628 1187 SUPERFAMILY SSF47336 658 738 3.14E-10 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS14730 fbc5c025a739dcab1a3472e7d7a02628 1187 Pfam PF00501 AMP-binding enzyme 88 520 2.0E-64 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK77_RS14730 fbc5c025a739dcab1a3472e7d7a02628 1187 SUPERFAMILY SSF51735 785 1094 1.93E-29 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS14730 fbc5c025a739dcab1a3472e7d7a02628 1187 Gene3D G3DSA:3.40.50.720 785 1016 2.2E-24 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS14730 fbc5c025a739dcab1a3472e7d7a02628 1187 Gene3D G3DSA:3.40.50.980 259 429 3.1E-22 T 06-07-2017 CAK77_RS14730 fbc5c025a739dcab1a3472e7d7a02628 1187 Pfam PF00550 Phosphopantetheine attachment site 664 729 4.7E-9 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS14730 fbc5c025a739dcab1a3472e7d7a02628 1187 Gene3D G3DSA:3.40.50.980 78 258 1.5E-23 T 06-07-2017 CAK77_RS14730 fbc5c025a739dcab1a3472e7d7a02628 1187 Gene3D G3DSA:2.30.38.10 441 512 6.2E-13 T 06-07-2017 CAK77_RS14730 fbc5c025a739dcab1a3472e7d7a02628 1187 SUPERFAMILY SSF56801 83 641 3.14E-87 T 06-07-2017 CAK77_RS14730 fbc5c025a739dcab1a3472e7d7a02628 1187 Pfam PF07993 Male sterility protein 788 1050 3.6E-51 T 06-07-2017 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 CAK77_RS14730 fbc5c025a739dcab1a3472e7d7a02628 1187 ProSitePatterns PS00455 Putative AMP-binding domain signature. 253 264 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK77_RS05790 09d3484e5b85cec2fc603e797c73f446 314 SUPERFAMILY SSF53067 3 130 2.75E-30 T 06-07-2017 CAK77_RS05790 09d3484e5b85cec2fc603e797c73f446 314 SUPERFAMILY SSF53067 136 313 6.12E-36 T 06-07-2017 CAK77_RS05790 09d3484e5b85cec2fc603e797c73f446 314 Pfam PF02541 Ppx/GppA phosphatase family 18 309 2.2E-75 T 06-07-2017 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 CAK77_RS05790 09d3484e5b85cec2fc603e797c73f446 314 Gene3D G3DSA:3.30.420.40 2 129 5.0E-45 T 06-07-2017 CAK77_RS05790 09d3484e5b85cec2fc603e797c73f446 314 Gene3D G3DSA:3.30.420.150 130 313 4.4E-57 T 06-07-2017 CAK77_RS03085 db5ad1884cd958b092099d4d3d36fe4f 386 SUPERFAMILY SSF47203 230 374 7.57E-19 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS03085 db5ad1884cd958b092099d4d3d36fe4f 386 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 120 2.1E-19 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS03085 db5ad1884cd958b092099d4d3d36fe4f 386 Gene3D G3DSA:1.20.140.10 220 376 2.3E-27 T 06-07-2017 CAK77_RS03085 db5ad1884cd958b092099d4d3d36fe4f 386 Gene3D G3DSA:2.40.110.10 123 219 8.6E-25 T 06-07-2017 CAK77_RS03085 db5ad1884cd958b092099d4d3d36fe4f 386 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 125 218 9.2E-16 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAK77_RS03085 db5ad1884cd958b092099d4d3d36fe4f 386 SUPERFAMILY SSF56645 2 239 7.98E-62 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK77_RS03085 db5ad1884cd958b092099d4d3d36fe4f 386 Gene3D G3DSA:1.10.540.10 5 122 3.3E-21 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS03085 db5ad1884cd958b092099d4d3d36fe4f 386 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 231 370 1.4E-18 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS23920 a9e8e2af8ed6add32c7f86a123739845 270 Pfam PF08924 Domain of unknown function (DUF1906) 64 191 1.6E-25 T 06-07-2017 IPR015020 Protein of unknown function DUF1906 CAK77_RS23920 a9e8e2af8ed6add32c7f86a123739845 270 SUPERFAMILY SSF51445 65 219 9.9E-5 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily CAK77_RS23920 a9e8e2af8ed6add32c7f86a123739845 270 Gene3D G3DSA:3.20.20.80 64 223 7.8E-10 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAK77_RS05940 c27b943a7133f944f76f71af4e500bc3 122 SMART SM00450 14 121 1.1E-7 T 06-07-2017 IPR001763 Rhodanese-like domain CAK77_RS05940 c27b943a7133f944f76f71af4e500bc3 122 Gene3D G3DSA:3.40.250.10 3 119 1.1E-13 T 06-07-2017 IPR001763 Rhodanese-like domain CAK77_RS05940 c27b943a7133f944f76f71af4e500bc3 122 SUPERFAMILY SSF52821 13 118 4.55E-13 T 06-07-2017 IPR001763 Rhodanese-like domain CAK77_RS05940 c27b943a7133f944f76f71af4e500bc3 122 Pfam PF00581 Rhodanese-like domain 21 117 4.4E-5 T 06-07-2017 IPR001763 Rhodanese-like domain CAK77_RS21840 0fa0c7b0709de23befd2f23dda9eca42 556 ProSitePatterns PS00455 Putative AMP-binding domain signature. 218 229 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK77_RS21840 0fa0c7b0709de23befd2f23dda9eca42 556 Gene3D G3DSA:3.40.50.980 65 224 2.5E-30 T 06-07-2017 CAK77_RS21840 0fa0c7b0709de23befd2f23dda9eca42 556 SUPERFAMILY SSF56801 64 554 5.89E-125 T 06-07-2017 CAK77_RS21840 0fa0c7b0709de23befd2f23dda9eca42 556 Pfam PF00501 AMP-binding enzyme 65 461 3.2E-73 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK77_RS21840 0fa0c7b0709de23befd2f23dda9eca42 556 Gene3D G3DSA:2.30.38.10 383 454 2.8E-11 T 06-07-2017 CAK77_RS21840 0fa0c7b0709de23befd2f23dda9eca42 556 Gene3D G3DSA:3.40.50.980 225 378 7.8E-31 T 06-07-2017 CAK77_RS21840 0fa0c7b0709de23befd2f23dda9eca42 556 Gene3D G3DSA:3.30.300.30 456 554 5.9E-32 T 06-07-2017 CAK77_RS21840 0fa0c7b0709de23befd2f23dda9eca42 556 Pfam PF13193 AMP-binding enzyme C-terminal domain 470 545 2.5E-17 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAK77_RS08555 5dbb74738b6fa903a050fca56d66fdae 119 Gene3D G3DSA:1.10.10.10 23 117 8.8E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS08555 5dbb74738b6fa903a050fca56d66fdae 119 Pfam PF01022 Bacterial regulatory protein, arsR family 43 87 1.0E-14 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK77_RS08555 5dbb74738b6fa903a050fca56d66fdae 119 SMART SM00418 35 113 8.5E-27 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK77_RS08555 5dbb74738b6fa903a050fca56d66fdae 119 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 69 84 9.1E-15 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK77_RS08555 5dbb74738b6fa903a050fca56d66fdae 119 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 37 52 9.1E-15 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK77_RS08555 5dbb74738b6fa903a050fca56d66fdae 119 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 56 67 9.1E-15 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK77_RS08555 5dbb74738b6fa903a050fca56d66fdae 119 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 84 99 9.1E-15 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK77_RS08555 5dbb74738b6fa903a050fca56d66fdae 119 SUPERFAMILY SSF46785 24 108 6.25E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS16520 9cd843433a5d83dbd780f8e124882f46 614 Gene3D G3DSA:3.40.50.970 30 205 1.5E-72 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK77_RS16520 9cd843433a5d83dbd780f8e124882f46 614 SUPERFAMILY SSF52467 214 389 1.4E-61 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAK77_RS16520 9cd843433a5d83dbd780f8e124882f46 614 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 221 356 3.8E-49 T 06-07-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CAK77_RS16520 9cd843433a5d83dbd780f8e124882f46 614 Gene3D G3DSA:3.40.50.970 394 597 5.3E-75 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK77_RS16520 9cd843433a5d83dbd780f8e124882f46 614 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 421 574 3.0E-51 T 06-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CAK77_RS16520 9cd843433a5d83dbd780f8e124882f46 614 SUPERFAMILY SSF52518 26 210 4.42E-61 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK77_RS16520 9cd843433a5d83dbd780f8e124882f46 614 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 458 477 - T 06-07-2017 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 CAK77_RS16520 9cd843433a5d83dbd780f8e124882f46 614 Gene3D G3DSA:3.40.50.1220 216 388 6.4E-68 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAK77_RS16520 9cd843433a5d83dbd780f8e124882f46 614 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 32 596 1.4E-230 T 06-07-2017 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 CAK77_RS16520 9cd843433a5d83dbd780f8e124882f46 614 SUPERFAMILY SSF52518 398 600 2.68E-68 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK77_RS16520 9cd843433a5d83dbd780f8e124882f46 614 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 32 197 1.5E-54 T 06-07-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CAK77_RS17240 a4ae5327efcf3a71dd0ca6e113a26d3e 158 SUPERFAMILY SSF53927 3 107 3.94E-25 T 06-07-2017 IPR016193 Cytidine deaminase-like GO:0003824 CAK77_RS17240 a4ae5327efcf3a71dd0ca6e113a26d3e 158 Gene3D G3DSA:3.40.140.10 3 153 6.1E-28 T 06-07-2017 CAK77_RS17240 a4ae5327efcf3a71dd0ca6e113a26d3e 158 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 5 102 6.7E-6 T 06-07-2017 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 CAK77_RS08115 6974d6e6035d6b654d58df3b576eba49 363 Gene3D G3DSA:3.10.20.30 266 362 3.5E-16 T 06-07-2017 IPR012675 Beta-grasp domain CAK77_RS08115 6974d6e6035d6b654d58df3b576eba49 363 Pfam PF00970 Oxidoreductase FAD-binding domain 57 143 1.6E-10 T 06-07-2017 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 CAK77_RS08115 6974d6e6035d6b654d58df3b576eba49 363 SUPERFAMILY SSF63380 40 146 1.45E-20 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CAK77_RS08115 6974d6e6035d6b654d58df3b576eba49 363 Gene3D G3DSA:2.40.30.10 35 141 1.2E-19 T 06-07-2017 CAK77_RS08115 6974d6e6035d6b654d58df3b576eba49 363 PRINTS PR00410 Phenol hydroxylase reductase family signature 238 246 3.1E-8 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 CAK77_RS08115 6974d6e6035d6b654d58df3b576eba49 363 PRINTS PR00410 Phenol hydroxylase reductase family signature 75 87 3.1E-8 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 CAK77_RS08115 6974d6e6035d6b654d58df3b576eba49 363 PRINTS PR00410 Phenol hydroxylase reductase family signature 154 173 3.1E-8 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 CAK77_RS08115 6974d6e6035d6b654d58df3b576eba49 363 Pfam PF00175 Oxidoreductase NAD-binding domain 155 252 4.6E-7 T 06-07-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CAK77_RS08115 6974d6e6035d6b654d58df3b576eba49 363 SUPERFAMILY SSF54292 262 362 2.49E-13 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK77_RS08115 6974d6e6035d6b654d58df3b576eba49 363 Gene3D G3DSA:3.40.50.80 151 265 3.5E-21 T 06-07-2017 CAK77_RS08115 6974d6e6035d6b654d58df3b576eba49 363 SUPERFAMILY SSF52343 149 270 3.27E-22 T 06-07-2017 CAK77_RS21605 2ec801e500da806b280c5334018db6f0 436 SUPERFAMILY SSF53383 38 434 3.73E-93 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK77_RS21605 2ec801e500da806b280c5334018db6f0 436 Gene3D G3DSA:3.40.640.10 82 312 1.4E-65 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK77_RS21605 2ec801e500da806b280c5334018db6f0 436 Gene3D G3DSA:3.90.1150.10 313 435 9.5E-37 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK77_RS21605 2ec801e500da806b280c5334018db6f0 436 Pfam PF00155 Aminotransferase class I and II 67 413 4.1E-46 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAK77_RS07365 441c2e0e4ff1a8618a1036f512cae7a9 117 Pfam PF12823 Domain of unknown function (DUF3817) 12 99 1.2E-23 T 06-07-2017 IPR023845 Domain of unknown function DUF3817, transmembrane CAK77_RS07365 441c2e0e4ff1a8618a1036f512cae7a9 117 TIGRFAM TIGR03954 integ_memb_HG: integral membrane protein 14 97 7.0E-25 T 06-07-2017 IPR023845 Domain of unknown function DUF3817, transmembrane CAK77_RS13165 8ba64ae1c3411bfb6573535266230f80 224 Pfam PF00440 Bacterial regulatory proteins, tetR family 32 76 3.6E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS13165 8ba64ae1c3411bfb6573535266230f80 224 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 43 2.7E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS13165 8ba64ae1c3411bfb6573535266230f80 224 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 51 74 2.7E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS13165 8ba64ae1c3411bfb6573535266230f80 224 PRINTS PR00400 Tetracycline repressor protein signature 94 113 6.2E-14 T 06-07-2017 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 CAK77_RS13165 8ba64ae1c3411bfb6573535266230f80 224 PRINTS PR00400 Tetracycline repressor protein signature 199 213 6.2E-14 T 06-07-2017 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 CAK77_RS13165 8ba64ae1c3411bfb6573535266230f80 224 PRINTS PR00400 Tetracycline repressor protein signature 42 65 6.2E-14 T 06-07-2017 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 CAK77_RS13165 8ba64ae1c3411bfb6573535266230f80 224 PRINTS PR00400 Tetracycline repressor protein signature 152 171 6.2E-14 T 06-07-2017 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 CAK77_RS13165 8ba64ae1c3411bfb6573535266230f80 224 Gene3D G3DSA:1.10.357.10 87 216 9.3E-26 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS13165 8ba64ae1c3411bfb6573535266230f80 224 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 90 214 1.0E-12 T 06-07-2017 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 CAK77_RS13165 8ba64ae1c3411bfb6573535266230f80 224 SUPERFAMILY SSF48498 89 219 3.0E-20 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS13165 8ba64ae1c3411bfb6573535266230f80 224 Gene3D G3DSA:1.10.10.60 14 84 9.2E-23 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS13165 8ba64ae1c3411bfb6573535266230f80 224 SUPERFAMILY SSF46689 19 86 4.81E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS24485 752d4e5eec485c0331bba788cc1f775e 646 SUPERFAMILY SSF81653 129 226 1.44E-25 T 06-07-2017 CAK77_RS24485 752d4e5eec485c0331bba788cc1f775e 646 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 446 457 9.7E-28 T 06-07-2017 CAK77_RS24485 752d4e5eec485c0331bba788cc1f775e 646 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 544 556 9.7E-28 T 06-07-2017 CAK77_RS24485 752d4e5eec485c0331bba788cc1f775e 646 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 521 540 9.7E-28 T 06-07-2017 CAK77_RS24485 752d4e5eec485c0331bba788cc1f775e 646 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 176 190 9.7E-28 T 06-07-2017 CAK77_RS24485 752d4e5eec485c0331bba788cc1f775e 646 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 468 478 9.7E-28 T 06-07-2017 CAK77_RS24485 752d4e5eec485c0331bba788cc1f775e 646 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 325 339 9.7E-28 T 06-07-2017 CAK77_RS24485 752d4e5eec485c0331bba788cc1f775e 646 Pfam PF00702 haloacid dehalogenase-like hydrolase 321 535 6.6E-40 T 06-07-2017 CAK77_RS24485 752d4e5eec485c0331bba788cc1f775e 646 SUPERFAMILY SSF56784 437 626 8.25E-56 T 06-07-2017 IPR023214 HAD-like domain CAK77_RS24485 752d4e5eec485c0331bba788cc1f775e 646 SUPERFAMILY SSF56784 323 404 8.25E-56 T 06-07-2017 IPR023214 HAD-like domain CAK77_RS24485 752d4e5eec485c0331bba788cc1f775e 646 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 327 333 - T 06-07-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CAK77_RS24485 752d4e5eec485c0331bba788cc1f775e 646 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 45 630 8.6E-166 T 06-07-2017 CAK77_RS24485 752d4e5eec485c0331bba788cc1f775e 646 Gene3D G3DSA:2.70.150.10 61 226 3.2E-27 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 CAK77_RS24485 752d4e5eec485c0331bba788cc1f775e 646 Gene3D G3DSA:3.40.1110.10 340 448 2.5E-14 T 06-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CAK77_RS24485 752d4e5eec485c0331bba788cc1f775e 646 Gene3D G3DSA:3.40.50.1000 298 339 1.4E-53 T 06-07-2017 IPR023214 HAD-like domain CAK77_RS24485 752d4e5eec485c0331bba788cc1f775e 646 Gene3D G3DSA:3.40.50.1000 449 589 1.4E-53 T 06-07-2017 IPR023214 HAD-like domain CAK77_RS24485 752d4e5eec485c0331bba788cc1f775e 646 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 552 577 2.1E-7 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CAK77_RS24485 752d4e5eec485c0331bba788cc1f775e 646 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 521 537 2.1E-7 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CAK77_RS24485 752d4e5eec485c0331bba788cc1f775e 646 SUPERFAMILY SSF81665 570 604 3.66E-13 T 06-07-2017 CAK77_RS24485 752d4e5eec485c0331bba788cc1f775e 646 SUPERFAMILY SSF81665 227 319 3.66E-13 T 06-07-2017 CAK77_RS24485 752d4e5eec485c0331bba788cc1f775e 646 SUPERFAMILY SSF81665 60 130 3.66E-13 T 06-07-2017 CAK77_RS24485 752d4e5eec485c0331bba788cc1f775e 646 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 99 600 2.9E-88 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CAK77_RS24485 752d4e5eec485c0331bba788cc1f775e 646 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 63 628 1.4E-170 T 06-07-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CAK77_RS24485 752d4e5eec485c0331bba788cc1f775e 646 Pfam PF00122 E1-E2 ATPase 97 316 3.5E-57 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 CAK77_RS12615 83ac632581efe2f34abd24641cd9ff67 477 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 167 181 1.0E-21 T 06-07-2017 CAK77_RS12615 83ac632581efe2f34abd24641cd9ff67 477 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 139 155 1.0E-21 T 06-07-2017 CAK77_RS12615 83ac632581efe2f34abd24641cd9ff67 477 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 248 260 1.0E-21 T 06-07-2017 CAK77_RS12615 83ac632581efe2f34abd24641cd9ff67 477 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 277 301 1.0E-21 T 06-07-2017 CAK77_RS12615 83ac632581efe2f34abd24641cd9ff67 477 Gene3D G3DSA:3.40.50.150 141 371 2.5E-40 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS12615 83ac632581efe2f34abd24641cd9ff67 477 Pfam PF12161 HsdM N-terminal domain 7 76 2.9E-8 T 06-07-2017 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain CAK77_RS12615 83ac632581efe2f34abd24641cd9ff67 477 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 251 257 - T 06-07-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CAK77_RS12615 83ac632581efe2f34abd24641cd9ff67 477 Pfam PF02384 N-6 DNA Methylase 116 433 1.0E-61 T 06-07-2017 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 CAK77_RS12615 83ac632581efe2f34abd24641cd9ff67 477 SUPERFAMILY SSF53335 5 470 9.14E-115 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS20015 a6e950424b53db598e17e94ddf003b4d 155 Pfam PF13452 N-terminal half of MaoC dehydratase 8 126 8.0E-18 T 06-07-2017 CAK77_RS20015 a6e950424b53db598e17e94ddf003b4d 155 Gene3D G3DSA:3.10.129.10 1 137 2.6E-19 T 06-07-2017 IPR029069 HotDog domain CAK77_RS20015 a6e950424b53db598e17e94ddf003b4d 155 PIRSF PIRSF018072 1 139 1.5E-38 T 06-07-2017 IPR016709 Uncharacterised protein family UPF0336 CAK77_RS20015 a6e950424b53db598e17e94ddf003b4d 155 SUPERFAMILY SSF54637 7 138 4.05E-29 T 06-07-2017 IPR029069 HotDog domain CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 SUPERFAMILY SSF47336 8211 8283 7.46E-16 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 3076 3465 2.0E-129 T 06-07-2017 IPR010071 Amino acid adenylation domain CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 5626 6016 1.6E-125 T 06-07-2017 IPR010071 Amino acid adenylation domain CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 486 891 1.2E-128 T 06-07-2017 IPR010071 Amino acid adenylation domain CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1556 1964 1.0E-130 T 06-07-2017 IPR010071 Amino acid adenylation domain CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 4132 4522 1.9E-123 T 06-07-2017 IPR010071 Amino acid adenylation domain CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 7741 8135 1.1E-126 T 06-07-2017 IPR010071 Amino acid adenylation domain CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 6682 7074 6.1E-125 T 06-07-2017 IPR010071 Amino acid adenylation domain CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 SUPERFAMILY SSF47336 6088 6161 3.8E-18 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 Gene3D G3DSA:1.10.1200.10 2049 2111 1.5E-20 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 Gene3D G3DSA:1.10.1200.10 8224 8284 1.7E-23 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 Gene3D G3DSA:1.10.1200.10 975 1037 6.3E-22 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 Gene3D G3DSA:1.10.1200.10 3550 3613 2.1E-26 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 Gene3D G3DSA:1.10.1200.10 4606 4667 4.6E-23 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 Gene3D G3DSA:1.10.1200.10 7159 7223 1.8E-24 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 Gene3D G3DSA:1.10.1200.10 6101 6163 6.2E-23 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 SUPERFAMILY SSF52777 8295 8482 2.78E-21 T 06-07-2017 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 SUPERFAMILY SSF56801 4070 4615 3.14E-140 T 06-07-2017 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 SUPERFAMILY SSF52777 6182 6357 7.11E-46 T 06-07-2017 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 SUPERFAMILY SSF52777 2127 2287 2.45E-24 T 06-07-2017 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 SUPERFAMILY SSF52777 8776 8971 3.56E-39 T 06-07-2017 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3569 3584 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 SUPERFAMILY SSF52777 5148 5345 1.56E-38 T 06-07-2017 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 Gene3D G3DSA:3.40.50.980 7715 7873 1.2E-45 T 06-07-2017 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 Gene3D G3DSA:3.40.50.980 1530 1683 4.1E-45 T 06-07-2017 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 Gene3D G3DSA:3.40.50.980 6655 6825 4.3E-47 T 06-07-2017 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 Gene3D G3DSA:3.40.50.980 3049 3214 4.9E-47 T 06-07-2017 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 Gene3D G3DSA:3.40.50.980 5599 5765 2.4E-44 T 06-07-2017 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 Gene3D G3DSA:3.40.50.980 4106 4261 2.3E-45 T 06-07-2017 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 ProSitePatterns PS00455 Putative AMP-binding domain signature. 605 616 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 SUPERFAMILY SSF47336 7146 7220 2.09E-18 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 ProSitePatterns PS00012 Phosphopantetheine attachment site. 7178 7193 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 Pfam PF13193 AMP-binding enzyme C-terminal domain 3449 3520 1.6E-9 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 Pfam PF13193 AMP-binding enzyme C-terminal domain 8119 8194 1.7E-9 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 Pfam PF13193 AMP-binding enzyme C-terminal domain 6000 6071 5.1E-6 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 Pfam PF13193 AMP-binding enzyme C-terminal domain 875 946 5.0E-7 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 Pfam PF13193 AMP-binding enzyme C-terminal domain 7058 7129 3.9E-10 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 Pfam PF13193 AMP-binding enzyme C-terminal domain 4506 4577 6.4E-8 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 Pfam PF13193 AMP-binding enzyme C-terminal domain 1948 2019 3.1E-9 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 SUPERFAMILY SSF52777 7240 7415 1.02E-44 T 06-07-2017 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 Gene3D G3DSA:3.40.50.980 460 609 9.6E-46 T 06-07-2017 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1675 1686 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 Pfam PF13745 HxxPF-repeated domain 6503 6604 5.3E-25 T 06-07-2017 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 Pfam PF13745 HxxPF-repeated domain 1378 1479 1.0E-25 T 06-07-2017 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 Pfam PF13745 HxxPF-repeated domain 7561 7664 6.9E-26 T 06-07-2017 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 Pfam PF13745 HxxPF-repeated domain 3952 4054 1.0E-23 T 06-07-2017 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 SUPERFAMILY SSF52777 2783 3017 1.67E-49 T 06-07-2017 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2068 2083 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 Pfam PF00501 AMP-binding enzyme 465 867 2.3E-86 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 Pfam PF00501 AMP-binding enzyme 7720 8111 2.5E-86 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 Pfam PF00501 AMP-binding enzyme 6661 7050 7.5E-89 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 Pfam PF00501 AMP-binding enzyme 4111 4498 4.4E-85 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 Pfam PF00501 AMP-binding enzyme 1535 1940 3.3E-88 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 Pfam PF00501 AMP-binding enzyme 5605 5992 1.6E-85 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 Pfam PF00501 AMP-binding enzyme 3057 3441 2.5E-85 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 ProSitePatterns PS00455 Putative AMP-binding domain signature. 5744 5755 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 Pfam PF00668 Condensation domain 1054 1356 1.3E-62 T 06-07-2017 IPR001242 Condensation domain CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 Pfam PF00668 Condensation domain 8408 8588 2.3E-16 T 06-07-2017 IPR001242 Condensation domain CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 Pfam PF00668 Condensation domain 4701 4970 9.7E-22 T 06-07-2017 IPR001242 Condensation domain CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 Pfam PF00668 Condensation domain 5151 5443 6.8E-52 T 06-07-2017 IPR001242 Condensation domain CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 Pfam PF00668 Condensation domain 6 300 2.1E-30 T 06-07-2017 IPR001242 Condensation domain CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 Pfam PF00668 Condensation domain 3629 3930 4.5E-61 T 06-07-2017 IPR001242 Condensation domain CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 Pfam PF00668 Condensation domain 2601 2893 1.1E-53 T 06-07-2017 IPR001242 Condensation domain CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 Pfam PF00668 Condensation domain 8779 9068 2.8E-52 T 06-07-2017 IPR001242 Condensation domain CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 Pfam PF00668 Condensation domain 7237 7539 4.6E-61 T 06-07-2017 IPR001242 Condensation domain CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 Pfam PF00668 Condensation domain 6179 6481 7.9E-63 T 06-07-2017 IPR001242 Condensation domain CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 Pfam PF00668 Condensation domain 2143 2422 2.4E-17 T 06-07-2017 IPR001242 Condensation domain CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 SMART SM00823 Phosphopantetheine attachment site 3545 3614 9.6E-10 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 SMART SM00823 Phosphopantetheine attachment site 6096 6165 4.4E-6 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 SMART SM00823 Phosphopantetheine attachment site 8219 8286 0.06 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 SMART SM00823 Phosphopantetheine attachment site 2044 2112 0.81 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 SMART SM00823 Phosphopantetheine attachment site 4602 4670 0.12 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 SMART SM00823 Phosphopantetheine attachment site 7154 7223 9.9E-8 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 SMART SM00823 Phosphopantetheine attachment site 971 1040 4.2E-4 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 SUPERFAMILY SSF52777 1057 1232 5.23E-45 T 06-07-2017 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 SUPERFAMILY SSF52777 1243 1497 1.22E-54 T 06-07-2017 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 ProSitePatterns PS00455 Putative AMP-binding domain signature. 6802 6813 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 SUPERFAMILY SSF47336 2036 2108 1.7E-14 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 SUPERFAMILY SSF47336 3537 3610 2.88E-20 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 Gene3D G3DSA:3.30.300.30 8106 8223 8.0E-37 T 06-07-2017 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 Gene3D G3DSA:3.30.300.30 862 974 2.0E-35 T 06-07-2017 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 Gene3D G3DSA:3.30.300.30 1935 2048 1.2E-38 T 06-07-2017 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 Gene3D G3DSA:3.30.300.30 5987 6100 6.3E-33 T 06-07-2017 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 Gene3D G3DSA:3.30.300.30 3436 3549 3.8E-37 T 06-07-2017 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 Gene3D G3DSA:3.30.300.30 4493 4605 2.0E-37 T 06-07-2017 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 Gene3D G3DSA:3.30.300.30 7045 7158 4.8E-37 T 06-07-2017 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 SUPERFAMILY SSF52777 4861 5121 1.78E-25 T 06-07-2017 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 Gene3D G3DSA:2.30.38.10 5905 5981 1.1E-21 T 06-07-2017 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 Gene3D G3DSA:2.30.38.10 8023 8100 6.1E-22 T 06-07-2017 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 Gene3D G3DSA:2.30.38.10 777 857 6.7E-17 T 06-07-2017 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 Gene3D G3DSA:2.30.38.10 4410 4487 5.6E-21 T 06-07-2017 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 Gene3D G3DSA:2.30.38.10 3354 3431 1.1E-21 T 06-07-2017 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 Gene3D G3DSA:2.30.38.10 1851 1929 8.4E-21 T 06-07-2017 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 Gene3D G3DSA:2.30.38.10 6960 7040 1.2E-22 T 06-07-2017 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 SUPERFAMILY SSF56801 1492 2057 2.09E-149 T 06-07-2017 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 ProSitePatterns PS00455 Putative AMP-binding domain signature. 4253 4264 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 SUPERFAMILY SSF52777 192 426 3.45E-24 T 06-07-2017 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 ProSitePatterns PS00012 Phosphopantetheine attachment site. 995 1010 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 Pfam PF00550 Phosphopantetheine attachment site 2047 2107 2.9E-6 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 Pfam PF00550 Phosphopantetheine attachment site 8221 8282 5.1E-9 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 Pfam PF00550 Phosphopantetheine attachment site 7157 7216 2.0E-13 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 Pfam PF00550 Phosphopantetheine attachment site 6099 6158 1.2E-12 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 Pfam PF00550 Phosphopantetheine attachment site 4604 4665 4.0E-7 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 Pfam PF00550 Phosphopantetheine attachment site 3548 3610 3.9E-15 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 Pfam PF00550 Phosphopantetheine attachment site 974 1033 1.0E-10 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 SUPERFAMILY SSF47336 963 1033 7.07E-18 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 SUPERFAMILY SSF52777 6369 6627 1.56E-54 T 06-07-2017 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 ProSitePatterns PS00012 Phosphopantetheine attachment site. 8243 8258 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 SUPERFAMILY SSF52777 2599 2795 3.78E-39 T 06-07-2017 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 SUPERFAMILY SSF56801 3012 3557 2.09E-147 T 06-07-2017 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 SUPERFAMILY SSF52777 10 183 7.56E-30 T 06-07-2017 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 SUPERFAMILY SSF52777 8472 8748 6.15E-21 T 06-07-2017 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 SUPERFAMILY SSF52777 3818 4076 1.89E-48 T 06-07-2017 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 ProSitePatterns PS00012 Phosphopantetheine attachment site. 6120 6135 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 SUPERFAMILY SSF56801 420 984 4.58E-142 T 06-07-2017 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 SUPERFAMILY SSF52777 2305 2571 1.89E-20 T 06-07-2017 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 SUPERFAMILY SSF52777 4689 4845 6.23E-23 T 06-07-2017 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 Gene3D G3DSA:3.40.50.980 610 776 1.0E-42 T 06-07-2017 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 Gene3D G3DSA:3.40.50.980 7874 8022 6.7E-37 T 06-07-2017 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 Gene3D G3DSA:3.40.50.980 4262 4409 3.7E-36 T 06-07-2017 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 Gene3D G3DSA:3.40.50.980 1684 1850 3.7E-42 T 06-07-2017 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 SUPERFAMILY SSF56801 7681 8232 1.7E-143 T 06-07-2017 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 SMART SM01294 6097 6161 0.0082 T 06-07-2017 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 SUPERFAMILY SSF52777 3631 3806 1.22E-48 T 06-07-2017 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 ProSitePatterns PS00455 Putative AMP-binding domain signature. 3194 3205 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 SUPERFAMILY SSF56801 6617 7167 8.63E-144 T 06-07-2017 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 Gene3D G3DSA:3.40.50.980 5766 5904 4.3E-39 T 06-07-2017 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 Gene3D G3DSA:3.40.50.980 3217 3353 7.8E-37 T 06-07-2017 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 Gene3D G3DSA:3.40.50.980 6826 6959 2.2E-34 T 06-07-2017 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 SUPERFAMILY SSF52777 8957 9188 7.23E-54 T 06-07-2017 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 SUPERFAMILY SSF47336 4594 4666 1.83E-15 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 SUPERFAMILY SSF52777 7426 7681 2.78E-56 T 06-07-2017 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 SUPERFAMILY SSF52777 5331 5567 3.34E-56 T 06-07-2017 CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 8611 8771 1.3E-31 T 06-07-2017 IPR010060 Non-ribosomal peptide synthase CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 2437 2593 5.4E-33 T 06-07-2017 IPR010060 Non-ribosomal peptide synthase CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 4987 5144 9.5E-31 T 06-07-2017 IPR010060 Non-ribosomal peptide synthase CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 ProSitePatterns PS00455 Putative AMP-binding domain signature. 7865 7876 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK77_RS23360 5496cabf9e1ffd55171e19c40dd85184 9191 SUPERFAMILY SSF56801 5562 6109 6.41E-146 T 06-07-2017 CAK77_RS03585 6bb76d17fd0edaa7be11028600e5be3c 467 ProSitePatterns PS00216 Sugar transport proteins signature 1. 317 334 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CAK77_RS03585 6bb76d17fd0edaa7be11028600e5be3c 467 ProSitePatterns PS00217 Sugar transport proteins signature 2. 112 137 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CAK77_RS03585 6bb76d17fd0edaa7be11028600e5be3c 467 Gene3D G3DSA:1.20.1250.20 20 206 1.2E-24 T 06-07-2017 CAK77_RS03585 6bb76d17fd0edaa7be11028600e5be3c 467 Gene3D G3DSA:1.20.1250.20 264 461 1.7E-21 T 06-07-2017 CAK77_RS03585 6bb76d17fd0edaa7be11028600e5be3c 467 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 14 461 2.1E-102 T 06-07-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CAK77_RS03585 6bb76d17fd0edaa7be11028600e5be3c 467 Pfam PF00083 Sugar (and other) transporter 17 464 2.2E-106 T 06-07-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CAK77_RS03585 6bb76d17fd0edaa7be11028600e5be3c 467 PRINTS PR00171 Sugar transporter signature 273 283 1.5E-26 T 06-07-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CAK77_RS03585 6bb76d17fd0edaa7be11028600e5be3c 467 PRINTS PR00171 Sugar transporter signature 24 34 1.5E-26 T 06-07-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CAK77_RS03585 6bb76d17fd0edaa7be11028600e5be3c 467 PRINTS PR00171 Sugar transporter signature 107 126 1.5E-26 T 06-07-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CAK77_RS03585 6bb76d17fd0edaa7be11028600e5be3c 467 PRINTS PR00171 Sugar transporter signature 392 404 1.5E-26 T 06-07-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CAK77_RS03585 6bb76d17fd0edaa7be11028600e5be3c 467 PRINTS PR00171 Sugar transporter signature 369 390 1.5E-26 T 06-07-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CAK77_RS03585 6bb76d17fd0edaa7be11028600e5be3c 467 SUPERFAMILY SSF103473 7 463 1.57E-66 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK77_RS19925 9cb329668eaebca65ade04fe8275661e 211 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 17 201 2.7E-38 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 CAK77_RS19925 9cb329668eaebca65ade04fe8275661e 211 SUPERFAMILY SSF53254 15 207 3.46E-39 T 06-07-2017 IPR029033 Histidine phosphatase superfamily CAK77_RS19925 9cb329668eaebca65ade04fe8275661e 211 SMART SM00855 16 168 2.5E-16 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 CAK77_RS19925 9cb329668eaebca65ade04fe8275661e 211 Gene3D G3DSA:3.40.50.1240 17 200 7.9E-36 T 06-07-2017 IPR029033 Histidine phosphatase superfamily CAK77_RS23385 fa191b39fbc2d1db505843770805dedb 302 SUPERFAMILY SSF53335 95 273 9.43E-27 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS23385 fa191b39fbc2d1db505843770805dedb 302 Pfam PF13489 Methyltransferase domain 95 239 2.4E-18 T 06-07-2017 CAK77_RS23385 fa191b39fbc2d1db505843770805dedb 302 Gene3D G3DSA:3.40.50.150 99 245 4.9E-21 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS04890 78ab2d9bdd7057cc1d4083d8eca0f9e4 222 SUPERFAMILY SSF46689 16 81 2.54E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS04890 78ab2d9bdd7057cc1d4083d8eca0f9e4 222 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 47 70 8.0E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS04890 78ab2d9bdd7057cc1d4083d8eca0f9e4 222 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 39 8.0E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS04890 78ab2d9bdd7057cc1d4083d8eca0f9e4 222 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 71 1.1E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS04890 78ab2d9bdd7057cc1d4083d8eca0f9e4 222 Gene3D G3DSA:1.10.357.10 70 204 4.9E-7 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS04890 78ab2d9bdd7057cc1d4083d8eca0f9e4 222 SUPERFAMILY SSF48498 88 205 3.34E-5 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS04890 78ab2d9bdd7057cc1d4083d8eca0f9e4 222 Gene3D G3DSA:1.10.10.60 17 69 7.4E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS18905 6c9c346309fe4222270dbf41e0a9fb4f 583 SUPERFAMILY SSF52096 50 144 1.66E-21 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS18905 6c9c346309fe4222270dbf41e0a9fb4f 583 SUPERFAMILY SSF52096 182 244 1.66E-21 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS18905 6c9c346309fe4222270dbf41e0a9fb4f 583 PIRSF PIRSF001217 1 581 1.5E-159 T 06-07-2017 IPR004634 Peptidase S49, protease IV GO:0006465|GO:0008233|GO:0016021 CAK77_RS18905 6c9c346309fe4222270dbf41e0a9fb4f 583 SUPERFAMILY SSF52096 440 500 1.45E-41 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS18905 6c9c346309fe4222270dbf41e0a9fb4f 583 SUPERFAMILY SSF52096 291 411 1.45E-41 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS18905 6c9c346309fe4222270dbf41e0a9fb4f 583 Pfam PF01343 Peptidase family S49 363 514 6.2E-51 T 06-07-2017 IPR002142 Peptidase S49 GO:0006508|GO:0008233 CAK77_RS18905 6c9c346309fe4222270dbf41e0a9fb4f 583 Pfam PF01343 Peptidase family S49 103 256 5.6E-38 T 06-07-2017 IPR002142 Peptidase S49 GO:0006508|GO:0008233 CAK77_RS18905 6c9c346309fe4222270dbf41e0a9fb4f 583 Gene3D G3DSA:3.40.1750.10 134 212 4.2E-17 T 06-07-2017 CAK77_RS18905 6c9c346309fe4222270dbf41e0a9fb4f 583 Gene3D G3DSA:3.90.226.10 217 261 2.9E-25 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS18905 6c9c346309fe4222270dbf41e0a9fb4f 583 Gene3D G3DSA:3.90.226.10 57 133 2.9E-25 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS18905 6c9c346309fe4222270dbf41e0a9fb4f 583 Gene3D G3DSA:3.90.226.10 441 519 4.2E-59 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS18905 6c9c346309fe4222270dbf41e0a9fb4f 583 Gene3D G3DSA:3.90.226.10 289 403 4.2E-59 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS18905 6c9c346309fe4222270dbf41e0a9fb4f 583 TIGRFAM TIGR00705 SppA_67K: signal peptide peptidase SppA, 67K type 30 561 5.2E-108 T 06-07-2017 IPR004634 Peptidase S49, protease IV GO:0006465|GO:0008233|GO:0016021 CAK77_RS18905 6c9c346309fe4222270dbf41e0a9fb4f 583 TIGRFAM TIGR00706 SppA_dom: signal peptide peptidase SppA, 36K type 323 512 3.7E-55 T 06-07-2017 IPR004635 Peptidase S49, SppA GO:0006508|GO:0008233 CAK77_RS10725 3846f6caff61042ea684d3562dab4198 134 TIGRFAM TIGR03666 Rv2061_F420: PPOX class probable F420-dependent enzyme, Rv2061 family 9 126 6.8E-36 T 06-07-2017 IPR019965 PPOX class F420-dependent enzyme, family Rv2061, putative CAK77_RS10725 3846f6caff61042ea684d3562dab4198 134 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 16 89 5.6E-10 T 06-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAK77_RS10725 3846f6caff61042ea684d3562dab4198 134 SUPERFAMILY SSF50475 16 109 5.64E-22 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS10725 3846f6caff61042ea684d3562dab4198 134 Gene3D G3DSA:2.30.110.10 13 125 2.7E-19 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS08165 5ff174bceda62c2d1e26987281c42a0f 188 SUPERFAMILY SSF53448 4 181 1.6E-23 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK77_RS08165 5ff174bceda62c2d1e26987281c42a0f 188 Hamap MF_00316 Molybdenum cofactor guanylyltransferase [mobA]. 2 184 20.193 T 06-07-2017 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 MetaCyc: PWY-5964|MetaCyc: PWY-7639 CAK77_RS08165 5ff174bceda62c2d1e26987281c42a0f 188 Gene3D G3DSA:3.90.550.10 1 184 1.0E-43 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK77_RS08165 5ff174bceda62c2d1e26987281c42a0f 188 Pfam PF12804 MobA-like NTP transferase domain 6 152 2.5E-28 T 06-07-2017 IPR025877 MobA-like NTP transferase CAK77_RS19220 7608d55e7ab6e6f51097947cc9d2a428 124 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 123 39.8 T 06-07-2017 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS19220 7608d55e7ab6e6f51097947cc9d2a428 124 PIRSF PIRSF002133 1 124 1.9E-54 T 06-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS19220 7608d55e7ab6e6f51097947cc9d2a428 124 SUPERFAMILY SSF50249 2 123 3.51E-52 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS19220 7608d55e7ab6e6f51097947cc9d2a428 124 Pfam PF00164 Ribosomal protein S12/S23 3 123 3.3E-43 T 06-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS19220 7608d55e7ab6e6f51097947cc9d2a428 124 ProSitePatterns PS00055 Ribosomal protein S12 signature. 43 50 - T 06-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS19220 7608d55e7ab6e6f51097947cc9d2a428 124 PRINTS PR01034 Ribosomal protein S12 signature 58 77 1.8E-58 T 06-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS19220 7608d55e7ab6e6f51097947cc9d2a428 124 PRINTS PR01034 Ribosomal protein S12 signature 77 94 1.8E-58 T 06-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS19220 7608d55e7ab6e6f51097947cc9d2a428 124 PRINTS PR01034 Ribosomal protein S12 signature 42 57 1.8E-58 T 06-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS19220 7608d55e7ab6e6f51097947cc9d2a428 124 PRINTS PR01034 Ribosomal protein S12 signature 94 110 1.8E-58 T 06-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS19220 7608d55e7ab6e6f51097947cc9d2a428 124 PRINTS PR01034 Ribosomal protein S12 signature 27 42 1.8E-58 T 06-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS19220 7608d55e7ab6e6f51097947cc9d2a428 124 PRINTS PR01034 Ribosomal protein S12 signature 110 122 1.8E-58 T 06-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS19220 7608d55e7ab6e6f51097947cc9d2a428 124 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 123 1.0E-67 T 06-07-2017 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS19220 7608d55e7ab6e6f51097947cc9d2a428 124 Gene3D G3DSA:2.40.50.140 1 123 2.0E-64 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS05990 415f155991cd2c985f9d3e5b96f73e98 335 SUPERFAMILY SSF52266 78 277 7.18E-30 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAK77_RS05990 415f155991cd2c985f9d3e5b96f73e98 335 Gene3D G3DSA:3.40.50.1110 79 272 2.7E-23 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAK77_RS05990 415f155991cd2c985f9d3e5b96f73e98 335 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 82 261 1.2E-19 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAK77_RS03355 8dad4dfb2048ded54e5e841b20b25327 187 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 8.8E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS03355 8dad4dfb2048ded54e5e841b20b25327 187 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 8.8E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS03355 8dad4dfb2048ded54e5e841b20b25327 187 SUPERFAMILY SSF46689 5 85 3.99E-19 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS03355 8dad4dfb2048ded54e5e841b20b25327 187 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 64 6.5E-14 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS03355 8dad4dfb2048ded54e5e841b20b25327 187 SUPERFAMILY SSF48498 85 185 1.21E-9 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS03355 8dad4dfb2048ded54e5e841b20b25327 187 Gene3D G3DSA:1.10.357.10 7 187 2.1E-40 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS04865 5c71a8837fb70841497fbf44523dcc1a 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 28 74 4.5E-16 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS04865 5c71a8837fb70841497fbf44523dcc1a 204 Gene3D G3DSA:1.10.357.10 71 198 1.3E-28 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS04865 5c71a8837fb70841497fbf44523dcc1a 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 49 72 1.1E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS04865 5c71a8837fb70841497fbf44523dcc1a 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 41 1.1E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS04865 5c71a8837fb70841497fbf44523dcc1a 204 ProSitePatterns PS01081 TetR-type HTH domain signature. 40 71 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CAK77_RS04865 5c71a8837fb70841497fbf44523dcc1a 204 Gene3D G3DSA:1.10.10.60 16 70 1.0E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS04865 5c71a8837fb70841497fbf44523dcc1a 204 Pfam PF16859 Bacterial transcriptional repressor C-terminal 86 195 3.6E-25 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS04865 5c71a8837fb70841497fbf44523dcc1a 204 SUPERFAMILY SSF46689 27 80 2.15E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS04865 5c71a8837fb70841497fbf44523dcc1a 204 SUPERFAMILY SSF48498 89 198 9.45E-20 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS21275 df12b951313b07683ec7119ea5f48cd6 498 Pfam PF02222 ATP-grasp domain 229 405 9.6E-36 T 06-07-2017 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type CAK77_RS21275 df12b951313b07683ec7119ea5f48cd6 498 Gene3D G3DSA:3.40.50.20 117 226 2.5E-25 T 06-07-2017 IPR016185 Pre-ATP-grasp domain CAK77_RS21275 df12b951313b07683ec7119ea5f48cd6 498 SUPERFAMILY SSF52440 116 216 5.47E-17 T 06-07-2017 IPR016185 Pre-ATP-grasp domain CAK77_RS21275 df12b951313b07683ec7119ea5f48cd6 498 SUPERFAMILY SSF56059 219 426 6.01E-45 T 06-07-2017 CAK77_RS21275 df12b951313b07683ec7119ea5f48cd6 498 Gene3D G3DSA:3.30.1490.20 229 304 8.5E-17 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CAK77_RS21275 df12b951313b07683ec7119ea5f48cd6 498 Gene3D G3DSA:3.30.470.20 305 496 5.9E-51 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAK77_RS21275 df12b951313b07683ec7119ea5f48cd6 498 SUPERFAMILY SSF51246 430 497 1.27E-8 T 06-07-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAK77_RS12305 951cc4c7b888b525a3cb7dd6782ea12b 702 Gene3D G3DSA:3.40.50.880 536 702 2.4E-44 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAK77_RS12305 951cc4c7b888b525a3cb7dd6782ea12b 702 SUPERFAMILY SSF52317 535 695 8.33E-22 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAK77_RS12305 951cc4c7b888b525a3cb7dd6782ea12b 702 Gene3D G3DSA:2.40.180.10 7 381 4.6E-178 T 06-07-2017 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAK77_RS12305 951cc4c7b888b525a3cb7dd6782ea12b 702 SUPERFAMILY SSF56634 5 514 7.98E-212 T 06-07-2017 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAK77_RS12305 951cc4c7b888b525a3cb7dd6782ea12b 702 PRINTS PR00067 Catalase signature 123 140 1.2E-70 T 06-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAK77_RS12305 951cc4c7b888b525a3cb7dd6782ea12b 702 PRINTS PR00067 Catalase signature 311 338 1.2E-70 T 06-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAK77_RS12305 951cc4c7b888b525a3cb7dd6782ea12b 702 PRINTS PR00067 Catalase signature 343 369 1.2E-70 T 06-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAK77_RS12305 951cc4c7b888b525a3cb7dd6782ea12b 702 PRINTS PR00067 Catalase signature 38 61 1.2E-70 T 06-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAK77_RS12305 951cc4c7b888b525a3cb7dd6782ea12b 702 PRINTS PR00067 Catalase signature 102 120 1.2E-70 T 06-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAK77_RS12305 951cc4c7b888b525a3cb7dd6782ea12b 702 PRINTS PR00067 Catalase signature 142 160 1.2E-70 T 06-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAK77_RS12305 951cc4c7b888b525a3cb7dd6782ea12b 702 Pfam PF06628 Catalase-related immune-responsive 440 503 5.4E-18 T 06-07-2017 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAK77_RS12305 951cc4c7b888b525a3cb7dd6782ea12b 702 Pfam PF00199 Catalase 25 410 9.9E-176 T 06-07-2017 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAK77_RS12305 951cc4c7b888b525a3cb7dd6782ea12b 702 ProSitePatterns PS00438 Catalase proximal active site signature. 61 77 - T 06-07-2017 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAK77_RS12305 951cc4c7b888b525a3cb7dd6782ea12b 702 PIRSF PIRSF038927 2 701 0.0 T 06-07-2017 IPR024712 Catalase, mono-functional, haem-containing, clade 2 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 CAK77_RS12305 951cc4c7b888b525a3cb7dd6782ea12b 702 Pfam PF01965 DJ-1/PfpI family 537 673 5.9E-13 T 06-07-2017 IPR002818 DJ-1/PfpI CAK77_RS12305 951cc4c7b888b525a3cb7dd6782ea12b 702 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 356 364 - T 06-07-2017 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAK77_RS12305 951cc4c7b888b525a3cb7dd6782ea12b 702 SMART SM01060 25 414 6.2E-268 T 06-07-2017 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAK77_RS02530 c588b1ef78ab55b472ec09eab7063f56 154 Gene3D G3DSA:1.10.10.10 2 88 2.4E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS02530 c588b1ef78ab55b472ec09eab7063f56 154 Pfam PF03551 Transcriptional regulator PadR-like family 14 82 2.8E-12 T 06-07-2017 IPR005149 Transcription regulator PadR, N-terminal CAK77_RS02530 c588b1ef78ab55b472ec09eab7063f56 154 SUPERFAMILY SSF46785 3 88 3.15E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS04575 c0a1808f39eb9cbb2e2c2f3da57f6ded 159 Gene3D G3DSA:3.10.180.10 19 147 5.8E-32 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK77_RS04575 c0a1808f39eb9cbb2e2c2f3da57f6ded 159 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 21 137 2.0E-11 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CAK77_RS04575 c0a1808f39eb9cbb2e2c2f3da57f6ded 159 SUPERFAMILY SSF54593 16 152 3.22E-33 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK77_RS09820 b1324d7b1af59ca311e1972b57be41ce 204 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 84 179 3.8E-11 T 06-07-2017 IPR003709 Peptidase M15B GO:0006508|GO:0008233 CAK77_RS09820 b1324d7b1af59ca311e1972b57be41ce 204 SUPERFAMILY SSF55166 76 187 3.4E-20 T 06-07-2017 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 CAK77_RS09820 b1324d7b1af59ca311e1972b57be41ce 204 Gene3D G3DSA:3.30.1380.10 77 160 1.3E-6 T 06-07-2017 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 CAK77_RS05515 be1869ef32c1aab8cfcbdbb4ad834597 129 Gene3D G3DSA:2.30.110.10 5 124 2.4E-14 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS05515 be1869ef32c1aab8cfcbdbb4ad834597 129 TIGRFAM TIGR03666 Rv2061_F420: PPOX class probable F420-dependent enzyme, Rv2061 family 6 127 1.2E-36 T 06-07-2017 IPR019965 PPOX class F420-dependent enzyme, family Rv2061, putative CAK77_RS05515 be1869ef32c1aab8cfcbdbb4ad834597 129 SUPERFAMILY SSF50475 5 108 1.74E-18 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS05515 be1869ef32c1aab8cfcbdbb4ad834597 129 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 9 84 1.8E-8 T 06-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAK77_RS13755 6a29796e9e0dc65260441a6d6f28734e 671 Hamap MF_00983 Probable primosomal protein N' [priA]. 19 670 20.926 T 06-07-2017 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 CAK77_RS00925 e5742364bcbddf8794d3343a2a3abb18 148 Pfam PF12796 Ankyrin repeats (3 copies) 36 124 1.2E-11 T 06-07-2017 IPR020683 Ankyrin repeat-containing domain CAK77_RS00925 e5742364bcbddf8794d3343a2a3abb18 148 SMART SM00248 63 92 0.0054 T 06-07-2017 IPR002110 Ankyrin repeat GO:0005515 CAK77_RS00925 e5742364bcbddf8794d3343a2a3abb18 148 SMART SM00248 96 125 0.017 T 06-07-2017 IPR002110 Ankyrin repeat GO:0005515 CAK77_RS00925 e5742364bcbddf8794d3343a2a3abb18 148 SUPERFAMILY SSF48403 35 146 1.55E-22 T 06-07-2017 IPR020683 Ankyrin repeat-containing domain CAK77_RS00925 e5742364bcbddf8794d3343a2a3abb18 148 Gene3D G3DSA:1.25.40.20 34 143 1.4E-23 T 06-07-2017 IPR020683 Ankyrin repeat-containing domain CAK77_RS18095 a817ce7b8816c12a388c36f9660630f9 170 TIGRFAM TIGR01313 therm_gnt_kin: carbohydrate kinase, thermoresistant glucokinase family 9 166 2.4E-58 T 06-07-2017 IPR006001 Carbohydrate kinase, thermoresistant glucokinase GO:0005975|GO:0016301 KEGG: 00030+2.7.1.12|MetaCyc: PWY-5530 CAK77_RS18095 a817ce7b8816c12a388c36f9660630f9 170 Gene3D G3DSA:3.40.50.300 4 168 1.1E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS18095 a817ce7b8816c12a388c36f9660630f9 170 Pfam PF01202 Shikimate kinase 16 123 6.5E-9 T 06-07-2017 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 CAK77_RS18095 a817ce7b8816c12a388c36f9660630f9 170 SUPERFAMILY SSF52540 5 166 2.23E-23 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS16945 aff1847d9d8f5721bf14314f377beaf9 220 Pfam PF06912 Protein of unknown function (DUF1275) 13 204 1.3E-34 T 06-07-2017 IPR010699 Protein of unknown function DUF1275 CAK77_RS13040 92a7a9d62e654d7de65720e81b14640b 939 TIGRFAM TIGR00833 actII: transport protein 18 926 1.8E-269 T 06-07-2017 IPR004707 Membrane transport protein MmpL family GO:0016021 CAK77_RS13040 92a7a9d62e654d7de65720e81b14640b 939 SUPERFAMILY SSF82866 717 926 6.02E-30 T 06-07-2017 CAK77_RS13040 92a7a9d62e654d7de65720e81b14640b 939 SUPERFAMILY SSF82866 151 347 5.89E-26 T 06-07-2017 CAK77_RS13040 92a7a9d62e654d7de65720e81b14640b 939 Gene3D G3DSA:1.20.1640.10 729 927 3.1E-22 T 06-07-2017 CAK77_RS13040 92a7a9d62e654d7de65720e81b14640b 939 Gene3D G3DSA:1.20.1640.10 150 352 2.5E-27 T 06-07-2017 CAK77_RS13040 92a7a9d62e654d7de65720e81b14640b 939 Pfam PF03176 MMPL family 604 935 4.0E-83 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 CAK77_RS13040 92a7a9d62e654d7de65720e81b14640b 939 Pfam PF03176 MMPL family 53 377 4.7E-97 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 CAK77_RS02840 cc7f14442fec698cdf694563f5e740b8 844 Pfam PF02151 UvrB/uvrC motif 425 458 5.7E-7 T 06-07-2017 IPR001943 UVR domain GO:0005515 CAK77_RS02840 cc7f14442fec698cdf694563f5e740b8 844 SMART SM01086 722 813 1.1E-34 T 06-07-2017 IPR019489 Clp ATPase, C-terminal CAK77_RS02840 cc7f14442fec698cdf694563f5e740b8 844 Gene3D G3DSA:3.40.50.300 703 733 1.0E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS02840 cc7f14442fec698cdf694563f5e740b8 844 Gene3D G3DSA:3.40.50.300 498 669 1.0E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS02840 cc7f14442fec698cdf694563f5e740b8 844 SUPERFAMILY SSF52540 494 807 3.47E-77 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS02840 cc7f14442fec698cdf694563f5e740b8 844 Gene3D G3DSA:1.10.8.60 734 806 4.2E-29 T 06-07-2017 CAK77_RS02840 cc7f14442fec698cdf694563f5e740b8 844 Gene3D G3DSA:1.10.8.60 352 436 1.2E-34 T 06-07-2017 CAK77_RS02840 cc7f14442fec698cdf694563f5e740b8 844 Pfam PF07724 AAA domain (Cdc48 subfamily) 544 716 7.6E-50 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 CAK77_RS02840 cc7f14442fec698cdf694563f5e740b8 844 SUPERFAMILY SSF52540 171 469 8.9E-74 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS02840 cc7f14442fec698cdf694563f5e740b8 844 SUPERFAMILY SSF81923 3 144 1.28E-31 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 CAK77_RS02840 cc7f14442fec698cdf694563f5e740b8 844 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 549 567 1.3E-38 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 CAK77_RS02840 cc7f14442fec698cdf694563f5e740b8 844 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 594 612 1.3E-38 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 CAK77_RS02840 cc7f14442fec698cdf694563f5e740b8 844 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 656 670 1.3E-38 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 CAK77_RS02840 cc7f14442fec698cdf694563f5e740b8 844 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 623 641 1.3E-38 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 CAK77_RS02840 cc7f14442fec698cdf694563f5e740b8 844 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 303 315 - T 06-07-2017 IPR018368 ClpA/B, conserved site 1 GO:0005524 CAK77_RS02840 cc7f14442fec698cdf694563f5e740b8 844 Gene3D G3DSA:1.10.1780.10 1 143 4.6E-52 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 CAK77_RS02840 cc7f14442fec698cdf694563f5e740b8 844 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 16 68 7.8E-18 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 CAK77_RS02840 cc7f14442fec698cdf694563f5e740b8 844 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 93 142 1.2E-15 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 CAK77_RS02840 cc7f14442fec698cdf694563f5e740b8 844 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 722 802 2.1E-24 T 06-07-2017 IPR019489 Clp ATPase, C-terminal CAK77_RS02840 cc7f14442fec698cdf694563f5e740b8 844 SMART SM00382 545 723 5.6E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS02840 cc7f14442fec698cdf694563f5e740b8 844 SMART SM00382 208 353 8.3E-8 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS02840 cc7f14442fec698cdf694563f5e740b8 844 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 213 325 2.8E-12 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 CAK77_RS02840 cc7f14442fec698cdf694563f5e740b8 844 Gene3D G3DSA:3.40.50.300 171 351 1.1E-45 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS02705 4f5519e7274b0ad6a04b4993759693f9 162 Pfam PF00719 Inorganic pyrophosphatase 5 157 3.6E-53 T 06-07-2017 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 CAK77_RS02705 4f5519e7274b0ad6a04b4993759693f9 162 SUPERFAMILY SSF50324 3 158 9.03E-60 T 06-07-2017 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 CAK77_RS02705 4f5519e7274b0ad6a04b4993759693f9 162 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 1 158 34.928 T 06-07-2017 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 CAK77_RS02705 4f5519e7274b0ad6a04b4993759693f9 162 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 52 58 - T 06-07-2017 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 CAK77_RS02705 4f5519e7274b0ad6a04b4993759693f9 162 Gene3D G3DSA:3.90.80.10 2 158 6.3E-54 T 06-07-2017 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 CAK77_RS04435 f35d065b584b4d60fa079854177fbc6d 167 ProDom PD034580 PRECURSOR SIGNAL EXPORTED MB0899C RV0875C/MT0898 MLCB57.27C POSSIBLE 27 165 1.0E-22 T 06-07-2017 IPR024495 Protein of unknown function DUF2771 CAK77_RS04435 f35d065b584b4d60fa079854177fbc6d 167 Pfam PF10969 Protein of unknown function (DUF2771) 6 163 9.0E-44 T 06-07-2017 IPR024495 Protein of unknown function DUF2771 CAK77_RS20800 ac6ba15a5078e74842999dca7ffca051 464 Pfam PF02470 MlaD protein 34 108 1.6E-11 T 06-07-2017 IPR003399 Mce/MlaD CAK77_RS20800 ac6ba15a5078e74842999dca7ffca051 464 SUPERFAMILY SSF58104 141 296 4.05E-5 T 06-07-2017 CAK77_RS20800 ac6ba15a5078e74842999dca7ffca051 464 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 162 284 6.9E-7 T 06-07-2017 IPR024516 Mammalian cell entry, C-terminal CAK77_RS20800 ac6ba15a5078e74842999dca7ffca051 464 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 13 297 3.8E-70 T 06-07-2017 IPR005693 Virulence factor Mce protein CAK77_RS11160 c6469d9734af697ad7b709a26cc9db51 493 Gene3D G3DSA:3.50.50.60 9 215 2.8E-54 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS11160 c6469d9734af697ad7b709a26cc9db51 493 Gene3D G3DSA:3.50.50.60 323 460 1.6E-5 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS11160 c6469d9734af697ad7b709a26cc9db51 493 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 180 198 5.4E-5 T 06-07-2017 CAK77_RS11160 c6469d9734af697ad7b709a26cc9db51 493 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 12 31 5.4E-5 T 06-07-2017 CAK77_RS11160 c6469d9734af697ad7b709a26cc9db51 493 SUPERFAMILY SSF51905 301 408 1.1E-47 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS11160 c6469d9734af697ad7b709a26cc9db51 493 SUPERFAMILY SSF51905 11 232 1.1E-47 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS11160 c6469d9734af697ad7b709a26cc9db51 493 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 13 211 2.5E-13 T 06-07-2017 CAK77_RS11160 c6469d9734af697ad7b709a26cc9db51 493 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 180 205 4.0E-9 T 06-07-2017 CAK77_RS11160 c6469d9734af697ad7b709a26cc9db51 493 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 11 33 4.0E-9 T 06-07-2017 CAK77_RS07445 03df429914d6b095dcc47ba3175053db 324 Gene3D G3DSA:3.40.50.1100 158 310 9.6E-62 T 06-07-2017 CAK77_RS07445 03df429914d6b095dcc47ba3175053db 324 Gene3D G3DSA:3.40.50.1100 1 50 9.6E-62 T 06-07-2017 CAK77_RS07445 03df429914d6b095dcc47ba3175053db 324 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 41 59 - T 06-07-2017 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 CAK77_RS07445 03df429914d6b095dcc47ba3175053db 324 Gene3D G3DSA:3.40.50.1100 51 152 7.6E-38 T 06-07-2017 CAK77_RS07445 03df429914d6b095dcc47ba3175053db 324 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 9 295 1.7E-61 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAK77_RS07445 03df429914d6b095dcc47ba3175053db 324 SUPERFAMILY SSF53686 2 306 1.83E-79 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAK77_RS07445 03df429914d6b095dcc47ba3175053db 324 TIGRFAM TIGR01136 cysKM: cysteine synthase 8 307 3.3E-110 T 06-07-2017 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 CAK77_RS23010 599169306d520019f994f2aa84793204 756 SUPERFAMILY SSF51726 411 753 9.16E-111 T 06-07-2017 CAK77_RS23010 599169306d520019f994f2aa84793204 756 Gene3D G3DSA:3.20.20.210 391 754 1.5E-120 T 06-07-2017 CAK77_RS23010 599169306d520019f994f2aa84793204 756 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 428 750 3.2E-149 T 06-07-2017 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CAK77_RS23010 599169306d520019f994f2aa84793204 756 TIGRFAM TIGR01371 met_syn_B12ind: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase 11 754 0.0 T 06-07-2017 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CAK77_RS23010 599169306d520019f994f2aa84793204 756 Pfam PF08267 Cobalamin-independent synthase, N-terminal domain 8 311 4.0E-106 T 06-07-2017 IPR013215 Cobalamin-independent methionine synthase MetE, N-terminal GO:0003871|GO:0008270|GO:0008652 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CAK77_RS23010 599169306d520019f994f2aa84793204 756 SUPERFAMILY SSF51726 8 392 3.4E-94 T 06-07-2017 CAK77_RS23010 599169306d520019f994f2aa84793204 756 Hamap MF_00172 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [metE]. 6 755 34.159 T 06-07-2017 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CAK77_RS23010 599169306d520019f994f2aa84793204 756 PIRSF PIRSF000382 5 756 0.0 T 06-07-2017 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CAK77_RS23010 599169306d520019f994f2aa84793204 756 Gene3D G3DSA:3.20.20.210 7 387 6.1E-134 T 06-07-2017 CAK77_RS06270 c25bec0c56b06e9b73e6a91a14e5f863 466 SUPERFAMILY SSF48557 6 463 1.73E-140 T 06-07-2017 IPR008948 L-Aspartase-like GO:0003824 CAK77_RS06270 c25bec0c56b06e9b73e6a91a14e5f863 466 Pfam PF00206 Lyase 14 340 1.4E-102 T 06-07-2017 IPR022761 Fumarate lyase, N-terminal CAK77_RS06270 c25bec0c56b06e9b73e6a91a14e5f863 466 PRINTS PR00149 Fumarate lyase superfamily signature 131 149 4.0E-34 T 06-07-2017 IPR000362 Fumarate lyase family CAK77_RS06270 c25bec0c56b06e9b73e6a91a14e5f863 466 PRINTS PR00149 Fumarate lyase superfamily signature 269 296 4.0E-34 T 06-07-2017 IPR000362 Fumarate lyase family CAK77_RS06270 c25bec0c56b06e9b73e6a91a14e5f863 466 PRINTS PR00149 Fumarate lyase superfamily signature 315 331 4.0E-34 T 06-07-2017 IPR000362 Fumarate lyase family CAK77_RS06270 c25bec0c56b06e9b73e6a91a14e5f863 466 PRINTS PR00149 Fumarate lyase superfamily signature 177 195 4.0E-34 T 06-07-2017 IPR000362 Fumarate lyase family CAK77_RS06270 c25bec0c56b06e9b73e6a91a14e5f863 466 Gene3D G3DSA:1.10.40.30 406 461 4.6E-20 T 06-07-2017 CAK77_RS06270 c25bec0c56b06e9b73e6a91a14e5f863 466 PRINTS PR00145 Argininosuccinate lyase family signature 130 152 1.2E-5 T 06-07-2017 CAK77_RS06270 c25bec0c56b06e9b73e6a91a14e5f863 466 PRINTS PR00145 Argininosuccinate lyase family signature 172 192 1.2E-5 T 06-07-2017 CAK77_RS06270 c25bec0c56b06e9b73e6a91a14e5f863 466 PRINTS PR00145 Argininosuccinate lyase family signature 315 331 1.2E-5 T 06-07-2017 CAK77_RS06270 c25bec0c56b06e9b73e6a91a14e5f863 466 Hamap MF_00743 Fumarate hydratase class II [fumC]. 6 464 79.291 T 06-07-2017 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CAK77_RS06270 c25bec0c56b06e9b73e6a91a14e5f863 466 Gene3D G3DSA:1.10.275.10 5 135 2.3E-54 T 06-07-2017 IPR024083 Fumarase/histidase, N-terminal CAK77_RS06270 c25bec0c56b06e9b73e6a91a14e5f863 466 ProSitePatterns PS00163 Fumarate lyases signature. 315 324 - T 06-07-2017 IPR020557 Fumarate lyase, conserved site GO:0003824 CAK77_RS06270 c25bec0c56b06e9b73e6a91a14e5f863 466 Pfam PF10415 Fumarase C C-terminus 406 462 1.2E-18 T 06-07-2017 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CAK77_RS06270 c25bec0c56b06e9b73e6a91a14e5f863 466 Gene3D G3DSA:1.20.200.10 136 400 3.9E-96 T 06-07-2017 CAK77_RS10010 ba799f89b5e2d3206e3693a374388a2c 574 Pfam PF07287 Protein of unknown function (DUF1446) 7 347 1.5E-134 T 06-07-2017 IPR010839 Protein of unknown function DUF1446 CAK77_RS01860 5bce0c03415d0146f415c320943ac39e 416 SUPERFAMILY SSF55931 29 248 3.04E-40 T 06-07-2017 CAK77_RS01860 5bce0c03415d0146f415c320943ac39e 416 SUPERFAMILY SSF55931 287 370 3.04E-40 T 06-07-2017 CAK77_RS01860 5bce0c03415d0146f415c320943ac39e 416 PIRSF PIRSF017901 8 414 2.2E-95 T 06-07-2017 CAK77_RS01860 5bce0c03415d0146f415c320943ac39e 416 Hamap MF_02034 Glutamate--cysteine ligase EgtA [egtA]. 12 395 28.62 T 06-07-2017 IPR017809 Glutamate--cysteine ligase EgtA, Actinobacteria GO:0004357|GO:0052699 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CAK77_RS01860 5bce0c03415d0146f415c320943ac39e 416 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 37 340 5.1E-61 T 06-07-2017 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CAK77_RS01860 5bce0c03415d0146f415c320943ac39e 416 TIGRFAM TIGR03444 EgtA_Cys_ligase: ergothioneine biosynthesis glutamate--cysteine ligase EgtA 24 397 3.7E-126 T 06-07-2017 IPR017809 Glutamate--cysteine ligase EgtA, Actinobacteria GO:0004357|GO:0052699 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CAK77_RS07835 0ce2a285f05bee7f76557ecbbe822ef0 333 Gene3D G3DSA:3.40.630.30 155 288 5.6E-18 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS07835 0ce2a285f05bee7f76557ecbbe822ef0 333 Pfam PF13302 Acetyltransferase (GNAT) domain 161 289 2.1E-8 T 06-07-2017 IPR000182 GNAT domain GO:0008080 CAK77_RS07835 0ce2a285f05bee7f76557ecbbe822ef0 333 Pfam PF00027 Cyclic nucleotide-binding domain 44 127 8.1E-15 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain CAK77_RS07835 0ce2a285f05bee7f76557ecbbe822ef0 333 SUPERFAMILY SSF55729 157 294 3.49E-19 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS07835 0ce2a285f05bee7f76557ecbbe822ef0 333 Gene3D G3DSA:2.60.120.10 19 144 5.7E-20 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK77_RS07835 0ce2a285f05bee7f76557ecbbe822ef0 333 ProSitePatterns PS00889 Cyclic nucleotide-binding domain signature 2. 91 108 - T 06-07-2017 IPR018488 Cyclic nucleotide-binding, conserved site CAK77_RS07835 0ce2a285f05bee7f76557ecbbe822ef0 333 SMART SM00100 24 144 2.2E-14 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain CAK77_RS07835 0ce2a285f05bee7f76557ecbbe822ef0 333 SUPERFAMILY SSF51206 18 141 1.96E-18 T 06-07-2017 IPR018490 Cyclic nucleotide-binding-like CAK77_RS01465 1ee70664b8f52c8149a5a2bdfb3f12cc 392 Gene3D G3DSA:1.20.1250.20 5 183 9.2E-28 T 06-07-2017 CAK77_RS01465 1ee70664b8f52c8149a5a2bdfb3f12cc 392 SUPERFAMILY SSF103473 7 372 2.22E-46 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK77_RS01465 1ee70664b8f52c8149a5a2bdfb3f12cc 392 Gene3D G3DSA:1.20.1250.20 197 371 1.5E-8 T 06-07-2017 CAK77_RS01465 1ee70664b8f52c8149a5a2bdfb3f12cc 392 Pfam PF07690 Major Facilitator Superfamily 9 281 1.7E-29 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK77_RS00350 ed493fc85a6d35a9619468d692ccb256 154 SUPERFAMILY SSF49879 49 153 1.15E-23 T 06-07-2017 IPR008984 SMAD/FHA domain GO:0005515 CAK77_RS00350 ed493fc85a6d35a9619468d692ccb256 154 SMART SM00240 81 131 1.5E-12 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CAK77_RS00350 ed493fc85a6d35a9619468d692ccb256 154 Gene3D G3DSA:2.60.200.20 55 152 1.5E-23 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CAK77_RS00350 ed493fc85a6d35a9619468d692ccb256 154 Pfam PF16697 Inner membrane component of T3SS, cytoplasmic domain 65 152 1.1E-15 T 06-07-2017 IPR032030 YscD, cytoplasmic domain CAK77_RS17685 5224d96e9aa3a779b8e04c079be82b0c 490 SUPERFAMILY SSF52540 81 373 1.19E-72 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS17685 5224d96e9aa3a779b8e04c079be82b0c 490 Pfam PF00270 DEAD/DEAH box helicase 31 206 4.2E-47 T 06-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CAK77_RS17685 5224d96e9aa3a779b8e04c079be82b0c 490 Gene3D G3DSA:3.40.50.300 6 233 7.7E-71 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS17685 5224d96e9aa3a779b8e04c079be82b0c 490 Pfam PF00271 Helicase conserved C-terminal domain 246 355 2.2E-28 T 06-07-2017 IPR001650 Helicase, C-terminal CAK77_RS17685 5224d96e9aa3a779b8e04c079be82b0c 490 SMART SM00490 274 355 1.6E-32 T 06-07-2017 IPR001650 Helicase, C-terminal CAK77_RS17685 5224d96e9aa3a779b8e04c079be82b0c 490 SMART SM00487 25 238 1.3E-49 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain CAK77_RS17685 5224d96e9aa3a779b8e04c079be82b0c 490 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 164 172 - T 06-07-2017 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site CAK77_RS17685 5224d96e9aa3a779b8e04c079be82b0c 490 Gene3D G3DSA:3.40.50.300 234 387 2.1E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS00455 868629f75b6a1d62932d89e510be33b4 403 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 145 338 1.9E-10 T 06-07-2017 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain CAK77_RS00455 868629f75b6a1d62932d89e510be33b4 403 Gene3D G3DSA:3.40.50.300 144 370 1.3E-23 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS00455 868629f75b6a1d62932d89e510be33b4 403 SUPERFAMILY SSF52540 144 371 6.08E-22 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS03010 6c1e49ed1cee91c8c483263f14d299a5 715 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 374 462 3.5E-9 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS03010 6c1e49ed1cee91c8c483263f14d299a5 715 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 14 111 7.3E-9 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS03010 6c1e49ed1cee91c8c483263f14d299a5 715 SUPERFAMILY SSF47203 211 349 3.22E-31 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS03010 6c1e49ed1cee91c8c483263f14d299a5 715 Gene3D G3DSA:2.40.110.10 465 561 2.8E-32 T 06-07-2017 CAK77_RS03010 6c1e49ed1cee91c8c483263f14d299a5 715 Gene3D G3DSA:1.10.540.10 386 463 6.0E-12 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS03010 6c1e49ed1cee91c8c483263f14d299a5 715 Gene3D G3DSA:1.10.540.10 13 119 9.8E-10 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS03010 6c1e49ed1cee91c8c483263f14d299a5 715 Gene3D G3DSA:1.20.140.10 562 715 5.9E-18 T 06-07-2017 CAK77_RS03010 6c1e49ed1cee91c8c483263f14d299a5 715 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 466 550 2.4E-19 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAK77_RS03010 6c1e49ed1cee91c8c483263f14d299a5 715 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 212 344 1.6E-19 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS03010 6c1e49ed1cee91c8c483263f14d299a5 715 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 572 711 5.5E-7 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS03010 6c1e49ed1cee91c8c483263f14d299a5 715 SUPERFAMILY SSF56645 386 585 2.49E-57 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK77_RS03010 6c1e49ed1cee91c8c483263f14d299a5 715 SUPERFAMILY SSF47203 573 714 9.71E-9 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS03010 6c1e49ed1cee91c8c483263f14d299a5 715 SUPERFAMILY SSF56645 13 127 1.97E-11 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK77_RS03010 6c1e49ed1cee91c8c483263f14d299a5 715 Gene3D G3DSA:1.20.140.10 211 348 4.4E-32 T 06-07-2017 CAK77_RS03455 5a89e7b33ce40d8b56efe6eee980ca9d 74 ProSitePatterns PS01047 Heavy-metal-associated domain. 8 37 - T 06-07-2017 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 CAK77_RS03455 5a89e7b33ce40d8b56efe6eee980ca9d 74 SUPERFAMILY SSF55008 2 70 5.24E-12 T 06-07-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CAK77_RS03455 5a89e7b33ce40d8b56efe6eee980ca9d 74 Gene3D G3DSA:3.30.70.100 4 66 4.8E-13 T 06-07-2017 CAK77_RS03455 5a89e7b33ce40d8b56efe6eee980ca9d 74 Pfam PF00403 Heavy-metal-associated domain 6 66 3.3E-9 T 06-07-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CAK77_RS21775 58bcf3ed0311e179738ef6d1aa93dd82 394 Gene3D G3DSA:3.40.50.1820 152 393 2.2E-32 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS21775 58bcf3ed0311e179738ef6d1aa93dd82 394 Pfam PF00326 Prolyl oligopeptidase family 250 393 8.8E-6 T 06-07-2017 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 CAK77_RS21775 58bcf3ed0311e179738ef6d1aa93dd82 394 SUPERFAMILY SSF53474 141 393 1.08E-31 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS09220 974a90a8833ddbf13f985766437820fb 367 SUPERFAMILY SSF53098 3 128 8.47E-31 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAK77_RS09220 974a90a8833ddbf13f985766437820fb 367 Gene3D G3DSA:3.40.50.1240 165 366 3.0E-58 T 06-07-2017 IPR029033 Histidine phosphatase superfamily CAK77_RS09220 974a90a8833ddbf13f985766437820fb 367 PIRSF PIRSF036922 1 367 1.2E-183 T 06-07-2017 IPR014636 RNase H, phosphoglycerate mutase domain-containing CAK77_RS09220 974a90a8833ddbf13f985766437820fb 367 Pfam PF13456 Reverse transcriptase-like 8 129 1.8E-23 T 06-07-2017 CAK77_RS09220 974a90a8833ddbf13f985766437820fb 367 SMART SM00855 168 322 2.2E-18 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 CAK77_RS09220 974a90a8833ddbf13f985766437820fb 367 SUPERFAMILY SSF53254 166 366 6.81E-55 T 06-07-2017 IPR029033 Histidine phosphatase superfamily CAK77_RS09220 974a90a8833ddbf13f985766437820fb 367 Gene3D G3DSA:3.30.420.10 3 133 3.9E-22 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAK77_RS09220 974a90a8833ddbf13f985766437820fb 367 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 169 361 4.0E-60 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 CAK77_RS05775 314d63eb5012bf4d2b60d9223e6676cd 430 SUPERFAMILY SSF54826 4 137 4.77E-51 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAK77_RS05775 314d63eb5012bf4d2b60d9223e6676cd 430 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 5 422 2.9E-201 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAK77_RS05775 314d63eb5012bf4d2b60d9223e6676cd 430 PRINTS PR00148 Enolase signature 37 51 2.6E-49 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAK77_RS05775 314d63eb5012bf4d2b60d9223e6676cd 430 PRINTS PR00148 Enolase signature 332 346 2.6E-49 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAK77_RS05775 314d63eb5012bf4d2b60d9223e6676cd 430 PRINTS PR00148 Enolase signature 160 173 2.6E-49 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAK77_RS05775 314d63eb5012bf4d2b60d9223e6676cd 430 PRINTS PR00148 Enolase signature 361 378 2.6E-49 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAK77_RS05775 314d63eb5012bf4d2b60d9223e6676cd 430 PRINTS PR00148 Enolase signature 106 122 2.6E-49 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAK77_RS05775 314d63eb5012bf4d2b60d9223e6676cd 430 PRINTS PR00148 Enolase signature 309 320 2.6E-49 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAK77_RS05775 314d63eb5012bf4d2b60d9223e6676cd 430 SMART SM01193 4 133 2.8E-87 T 06-07-2017 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAK77_RS05775 314d63eb5012bf4d2b60d9223e6676cd 430 SMART SM01192 138 423 4.9E-207 T 06-07-2017 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAK77_RS05775 314d63eb5012bf4d2b60d9223e6676cd 430 Hamap MF_00318 Enolase [eno]. 2 409 44.991 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAK77_RS05775 314d63eb5012bf4d2b60d9223e6676cd 430 Gene3D G3DSA:3.30.390.10 5 124 4.7E-53 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAK77_RS05775 314d63eb5012bf4d2b60d9223e6676cd 430 Pfam PF03952 Enolase, N-terminal domain 5 133 5.9E-56 T 06-07-2017 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAK77_RS05775 314d63eb5012bf4d2b60d9223e6676cd 430 Gene3D G3DSA:3.20.20.120 129 421 3.9E-127 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAK77_RS05775 314d63eb5012bf4d2b60d9223e6676cd 430 ProSitePatterns PS00164 Enolase signature. 332 345 - T 06-07-2017 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK77_RS05775 314d63eb5012bf4d2b60d9223e6676cd 430 Pfam PF00113 Enolase, C-terminal TIM barrel domain 139 418 9.1E-125 T 06-07-2017 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAK77_RS05775 314d63eb5012bf4d2b60d9223e6676cd 430 SUPERFAMILY SSF51604 137 418 2.72E-121 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAK77_RS05775 314d63eb5012bf4d2b60d9223e6676cd 430 PIRSF PIRSF001400 2 421 3.2E-187 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAK77_RS14015 f3e0935149d2cb56a8460cf315ddb820 597 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 3 581 1.2E-204 T 06-07-2017 IPR004524 Aspartate-tRNA ligase, bacterial/mitochondrial-type GO:0005524|GO:0016874 Reactome: R-HSA-379726 CAK77_RS14015 f3e0935149d2cb56a8460cf315ddb820 597 Pfam PF02938 GAD domain 310 390 1.4E-12 T 06-07-2017 IPR029351 GAD domain Reactome: R-HSA-379726 CAK77_RS14015 f3e0935149d2cb56a8460cf315ddb820 597 Gene3D G3DSA:2.40.50.140 3 105 3.5E-37 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS14015 f3e0935149d2cb56a8460cf315ddb820 597 SUPERFAMILY SSF50249 2 104 5.52E-29 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS14015 f3e0935149d2cb56a8460cf315ddb820 597 SUPERFAMILY SSF55681 396 556 1.18E-95 T 06-07-2017 CAK77_RS14015 f3e0935149d2cb56a8460cf315ddb820 597 SUPERFAMILY SSF55681 117 309 1.18E-95 T 06-07-2017 CAK77_RS14015 f3e0935149d2cb56a8460cf315ddb820 597 PRINTS PR01042 Aspartyl-tRNA synthetase signature 518 532 1.0E-25 T 06-07-2017 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK77_RS14015 f3e0935149d2cb56a8460cf315ddb820 597 PRINTS PR01042 Aspartyl-tRNA synthetase signature 206 219 1.0E-25 T 06-07-2017 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK77_RS14015 f3e0935149d2cb56a8460cf315ddb820 597 PRINTS PR01042 Aspartyl-tRNA synthetase signature 474 490 1.0E-25 T 06-07-2017 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK77_RS14015 f3e0935149d2cb56a8460cf315ddb820 597 PRINTS PR01042 Aspartyl-tRNA synthetase signature 189 201 1.0E-25 T 06-07-2017 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK77_RS14015 f3e0935149d2cb56a8460cf315ddb820 597 Gene3D G3DSA:3.30.1360.30 275 403 3.9E-41 T 06-07-2017 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 CAK77_RS14015 f3e0935149d2cb56a8460cf315ddb820 597 Gene3D G3DSA:3.30.930.10 135 274 1.7E-104 T 06-07-2017 CAK77_RS14015 f3e0935149d2cb56a8460cf315ddb820 597 Gene3D G3DSA:3.30.930.10 404 584 1.7E-104 T 06-07-2017 CAK77_RS14015 f3e0935149d2cb56a8460cf315ddb820 597 Hamap MF_00044 Aspartate--tRNA(Asp) ligase [aspS]. 2 563 35.608 T 06-07-2017 CAK77_RS14015 f3e0935149d2cb56a8460cf315ddb820 597 Pfam PF00152 tRNA synthetases class II (D, K and N) 117 557 1.4E-98 T 06-07-2017 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK77_RS14015 f3e0935149d2cb56a8460cf315ddb820 597 SUPERFAMILY SSF55261 287 409 2.14E-32 T 06-07-2017 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 CAK77_RS14015 f3e0935149d2cb56a8460cf315ddb820 597 Pfam PF01336 OB-fold nucleic acid binding domain 19 101 3.7E-16 T 06-07-2017 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CAK77_RS21330 4b940823e529e9bdba1c65d3896860f5 424 Gene3D G3DSA:3.40.50.150 145 420 4.9E-94 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS21330 4b940823e529e9bdba1c65d3896860f5 424 PIRSF PIRSF003085 32 424 5.7E-125 T 06-07-2017 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 CAK77_RS21330 4b940823e529e9bdba1c65d3896860f5 424 Pfam PF02353 Mycolic acid cyclopropane synthetase 146 417 3.0E-96 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS21330 4b940823e529e9bdba1c65d3896860f5 424 SUPERFAMILY SSF53335 153 421 2.59E-68 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS10320 f9f5cadf31dfde401d69476eca1b0760 1509 SUPERFAMILY SSF47336 965 1036 1.11E-12 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS10320 f9f5cadf31dfde401d69476eca1b0760 1509 Gene3D G3DSA:3.30.300.30 855 953 2.4E-28 T 06-07-2017 CAK77_RS10320 f9f5cadf31dfde401d69476eca1b0760 1509 SUPERFAMILY SSF52777 188 424 4.45E-41 T 06-07-2017 CAK77_RS10320 f9f5cadf31dfde401d69476eca1b0760 1509 SUPERFAMILY SSF52777 8 185 1.67E-39 T 06-07-2017 CAK77_RS10320 f9f5cadf31dfde401d69476eca1b0760 1509 SUPERFAMILY SSF56801 450 983 7.72E-124 T 06-07-2017 CAK77_RS10320 f9f5cadf31dfde401d69476eca1b0760 1509 SMART SM00823 Phosphopantetheine attachment site 971 1040 5.1E-5 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAK77_RS10320 f9f5cadf31dfde401d69476eca1b0760 1509 Pfam PF00501 AMP-binding enzyme 462 861 5.4E-80 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK77_RS10320 f9f5cadf31dfde401d69476eca1b0760 1509 ProSitePatterns PS00455 Putative AMP-binding domain signature. 606 617 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK77_RS10320 f9f5cadf31dfde401d69476eca1b0760 1509 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 484 885 3.5E-108 T 06-07-2017 IPR010071 Amino acid adenylation domain CAK77_RS10320 f9f5cadf31dfde401d69476eca1b0760 1509 Gene3D G3DSA:2.30.38.10 774 850 1.4E-22 T 06-07-2017 CAK77_RS10320 f9f5cadf31dfde401d69476eca1b0760 1509 Pfam PF00668 Condensation domain 11 301 1.2E-59 T 06-07-2017 IPR001242 Condensation domain CAK77_RS10320 f9f5cadf31dfde401d69476eca1b0760 1509 Pfam PF00668 Condensation domain 1074 1356 3.4E-25 T 06-07-2017 IPR001242 Condensation domain CAK77_RS10320 f9f5cadf31dfde401d69476eca1b0760 1509 SUPERFAMILY SSF52777 1239 1507 1.26E-20 T 06-07-2017 CAK77_RS10320 f9f5cadf31dfde401d69476eca1b0760 1509 Pfam PF13193 AMP-binding enzyme C-terminal domain 869 942 1.3E-8 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAK77_RS10320 f9f5cadf31dfde401d69476eca1b0760 1509 Gene3D G3DSA:3.40.50.980 611 773 3.0E-26 T 06-07-2017 CAK77_RS10320 f9f5cadf31dfde401d69476eca1b0760 1509 Gene3D G3DSA:1.10.1200.10 962 1039 1.8E-18 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS10320 f9f5cadf31dfde401d69476eca1b0760 1509 Gene3D G3DSA:3.40.50.980 458 610 3.1E-42 T 06-07-2017 CAK77_RS10320 f9f5cadf31dfde401d69476eca1b0760 1509 Pfam PF00550 Phosphopantetheine attachment site 975 1036 6.5E-10 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS10320 f9f5cadf31dfde401d69476eca1b0760 1509 SUPERFAMILY SSF52777 1052 1250 1.89E-24 T 06-07-2017 CAK77_RS16635 9bc54b487df44b6b2d47a146ed013764 681 SMART SM00292 601 678 2.7E-13 T 06-07-2017 IPR001357 BRCT domain CAK77_RS16635 9bc54b487df44b6b2d47a146ed013764 681 Gene3D G3DSA:1.10.287.610 3 66 4.6E-26 T 06-07-2017 CAK77_RS16635 9bc54b487df44b6b2d47a146ed013764 681 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 604 674 3.5E-12 T 06-07-2017 IPR001357 BRCT domain CAK77_RS16635 9bc54b487df44b6b2d47a146ed013764 681 SUPERFAMILY SSF47781 405 592 5.08E-51 T 06-07-2017 IPR010994 RuvA domain 2-like CAK77_RS16635 9bc54b487df44b6b2d47a146ed013764 681 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 333 348 - T 06-07-2017 IPR033136 NAD-dependent DNA ligase, conserved site CAK77_RS16635 9bc54b487df44b6b2d47a146ed013764 681 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 12 670 9.8E-241 T 06-07-2017 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 CAK77_RS16635 9bc54b487df44b6b2d47a146ed013764 681 Pfam PF12826 Helix-hairpin-helix motif 519 582 1.3E-21 T 06-07-2017 CAK77_RS16635 9bc54b487df44b6b2d47a146ed013764 681 SUPERFAMILY SSF50249 319 402 2.57E-26 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS16635 9bc54b487df44b6b2d47a146ed013764 681 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 115 144 - T 06-07-2017 IPR018239 NAD-dependent DNA ligase, active site CAK77_RS16635 9bc54b487df44b6b2d47a146ed013764 681 SUPERFAMILY SSF52113 604 676 1.29E-16 T 06-07-2017 IPR001357 BRCT domain CAK77_RS16635 9bc54b487df44b6b2d47a146ed013764 681 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 5 320 9.9E-125 T 06-07-2017 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 CAK77_RS16635 9bc54b487df44b6b2d47a146ed013764 681 Gene3D G3DSA:1.10.150.20 513 592 5.3E-28 T 06-07-2017 CAK77_RS16635 9bc54b487df44b6b2d47a146ed013764 681 SUPERFAMILY SSF56091 4 318 1.1E-110 T 06-07-2017 CAK77_RS16635 9bc54b487df44b6b2d47a146ed013764 681 Gene3D G3DSA:1.10.150.20 438 495 3.3E-14 T 06-07-2017 CAK77_RS16635 9bc54b487df44b6b2d47a146ed013764 681 Hamap MF_01588 DNA ligase [ligA]. 3 675 50.994 T 06-07-2017 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 CAK77_RS16635 9bc54b487df44b6b2d47a146ed013764 681 SMART SM00532 4 451 1.6E-260 T 06-07-2017 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 CAK77_RS16635 9bc54b487df44b6b2d47a146ed013764 681 Gene3D G3DSA:3.40.50.10190 603 678 8.0E-22 T 06-07-2017 IPR001357 BRCT domain CAK77_RS16635 9bc54b487df44b6b2d47a146ed013764 681 Gene3D G3DSA:3.30.470.30 119 254 7.0E-47 T 06-07-2017 CAK77_RS16635 9bc54b487df44b6b2d47a146ed013764 681 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 323 400 9.6E-31 T 06-07-2017 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 CAK77_RS16635 9bc54b487df44b6b2d47a146ed013764 681 PIRSF PIRSF001604 1 679 1.5E-228 T 06-07-2017 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 CAK77_RS16635 9bc54b487df44b6b2d47a146ed013764 681 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 410 437 1.9E-8 T 06-07-2017 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 CAK77_RS16635 9bc54b487df44b6b2d47a146ed013764 681 Gene3D G3DSA:2.40.50.140 321 392 3.7E-30 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS12000 b14678429cced600849ce1ea659cd245 738 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 272 295 1.7E-49 T 06-07-2017 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 CAK77_RS12000 b14678429cced600849ce1ea659cd245 738 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 62 75 1.7E-49 T 06-07-2017 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 CAK77_RS12000 b14678429cced600849ce1ea659cd245 738 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 485 511 1.7E-49 T 06-07-2017 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 CAK77_RS12000 b14678429cced600849ce1ea659cd245 738 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 77 102 1.7E-49 T 06-07-2017 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 CAK77_RS12000 b14678429cced600849ce1ea659cd245 738 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 36 58 1.7E-49 T 06-07-2017 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 CAK77_RS12000 b14678429cced600849ce1ea659cd245 738 PRINTS PR00458 Haem peroxidase superfamily signature 323 338 4.1E-19 T 06-07-2017 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 CAK77_RS12000 b14678429cced600849ce1ea659cd245 738 PRINTS PR00458 Haem peroxidase superfamily signature 160 177 4.1E-19 T 06-07-2017 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 CAK77_RS12000 b14678429cced600849ce1ea659cd245 738 PRINTS PR00458 Haem peroxidase superfamily signature 100 114 4.1E-19 T 06-07-2017 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 CAK77_RS12000 b14678429cced600849ce1ea659cd245 738 PRINTS PR00458 Haem peroxidase superfamily signature 264 279 4.1E-19 T 06-07-2017 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 CAK77_RS12000 b14678429cced600849ce1ea659cd245 738 PRINTS PR00458 Haem peroxidase superfamily signature 178 190 4.1E-19 T 06-07-2017 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 CAK77_RS12000 b14678429cced600849ce1ea659cd245 738 Pfam PF00141 Peroxidase 412 712 1.8E-34 T 06-07-2017 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 CAK77_RS12000 b14678429cced600849ce1ea659cd245 738 Pfam PF00141 Peroxidase 91 399 1.0E-43 T 06-07-2017 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 CAK77_RS12000 b14678429cced600849ce1ea659cd245 738 ProSitePatterns PS00436 Peroxidases active site signature. 100 111 - T 06-07-2017 IPR019794 Peroxidase, active site GO:0004601|GO:0055114 CAK77_RS12000 b14678429cced600849ce1ea659cd245 738 ProSitePatterns PS00435 Peroxidases proximal heme-ligand signature. 264 274 - T 06-07-2017 IPR019793 Peroxidases heam-ligand binding site Reactome: R-HSA-2408557 CAK77_RS12000 b14678429cced600849ce1ea659cd245 738 Gene3D G3DSA:1.10.520.10 716 737 4.3E-58 T 06-07-2017 CAK77_RS12000 b14678429cced600849ce1ea659cd245 738 Gene3D G3DSA:1.10.520.10 440 590 4.3E-58 T 06-07-2017 CAK77_RS12000 b14678429cced600849ce1ea659cd245 738 Gene3D G3DSA:1.10.420.10 591 713 5.9E-46 T 06-07-2017 CAK77_RS12000 b14678429cced600849ce1ea659cd245 738 Hamap MF_01961 Catalase-peroxidase [katG]. 14 738 40.652 T 06-07-2017 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 CAK77_RS12000 b14678429cced600849ce1ea659cd245 738 Gene3D G3DSA:1.10.520.10 232 256 7.3E-69 T 06-07-2017 CAK77_RS12000 b14678429cced600849ce1ea659cd245 738 Gene3D G3DSA:1.10.520.10 57 200 7.3E-69 T 06-07-2017 CAK77_RS12000 b14678429cced600849ce1ea659cd245 738 TIGRFAM TIGR00198 cat_per_HPI: catalase/peroxidase HPI 33 737 0.0 T 06-07-2017 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 CAK77_RS12000 b14678429cced600849ce1ea659cd245 738 Gene3D G3DSA:1.10.420.10 257 279 5.3E-39 T 06-07-2017 CAK77_RS12000 b14678429cced600849ce1ea659cd245 738 Gene3D G3DSA:1.10.420.10 315 413 5.3E-39 T 06-07-2017 CAK77_RS12000 b14678429cced600849ce1ea659cd245 738 SUPERFAMILY SSF48113 436 737 4.13E-106 T 06-07-2017 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 CAK77_RS12000 b14678429cced600849ce1ea659cd245 738 SUPERFAMILY SSF48113 33 436 1.77E-145 T 06-07-2017 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 CAK77_RS00955 e09e7f0837c2bb35681b3e28272d4e55 237 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 135 189 3.1E-7 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 CAK77_RS00955 e09e7f0837c2bb35681b3e28272d4e55 237 SUPERFAMILY SSF52540 32 207 3.38E-19 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS00955 e09e7f0837c2bb35681b3e28272d4e55 237 SMART SM00382 35 204 2.0E-6 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS00955 e09e7f0837c2bb35681b3e28272d4e55 237 Pfam PF13476 AAA domain 33 65 2.2E-7 T 06-07-2017 CAK77_RS00955 e09e7f0837c2bb35681b3e28272d4e55 237 Gene3D G3DSA:3.40.50.300 32 63 1.6E-8 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS00955 e09e7f0837c2bb35681b3e28272d4e55 237 Gene3D G3DSA:3.40.50.300 126 204 4.6E-10 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS12920 c85bccb87c5916c87727015807f71412 205 Gene3D G3DSA:1.10.10.10 144 200 4.9E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS12920 c85bccb87c5916c87727015807f71412 205 SMART SM00448 14 125 5.4E-37 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK77_RS12920 c85bccb87c5916c87727015807f71412 205 Pfam PF03861 ANTAR domain 144 195 1.1E-18 T 06-07-2017 IPR005561 ANTAR domain GO:0003723 CAK77_RS12920 c85bccb87c5916c87727015807f71412 205 SUPERFAMILY SSF52172 13 196 8.11E-56 T 06-07-2017 IPR011006 CheY-like superfamily CAK77_RS12920 c85bccb87c5916c87727015807f71412 205 Pfam PF00072 Response regulator receiver domain 16 125 8.0E-29 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK77_RS12920 c85bccb87c5916c87727015807f71412 205 SMART SM01012 141 196 3.7E-22 T 06-07-2017 IPR005561 ANTAR domain GO:0003723 CAK77_RS12920 c85bccb87c5916c87727015807f71412 205 Gene3D G3DSA:3.40.50.2300 5 131 6.5E-38 T 06-07-2017 CAK77_RS12920 c85bccb87c5916c87727015807f71412 205 PIRSF PIRSF036382 5 202 4.7E-72 T 06-07-2017 IPR008327 Signal transduction response regulator, antiterminator CAK77_RS07050 1f47ad425c52fbad5d4d03914250a249 277 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 167 186 1.6E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS07050 1f47ad425c52fbad5d4d03914250a249 277 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 94 105 1.6E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS07050 1f47ad425c52fbad5d4d03914250a249 277 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 147 155 1.6E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS07050 1f47ad425c52fbad5d4d03914250a249 277 TIGRFAM TIGR03971 SDR_subfam_1: SDR family mycofactocin-dependent oxidoreductase 4 274 7.4E-98 T 06-07-2017 IPR023985 Mycofactocin-dependent oxidoreductase CAK77_RS07050 1f47ad425c52fbad5d4d03914250a249 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 236 256 4.8E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS07050 1f47ad425c52fbad5d4d03914250a249 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 186 4.8E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS07050 1f47ad425c52fbad5d4d03914250a249 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 188 205 4.8E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS07050 1f47ad425c52fbad5d4d03914250a249 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 141 157 4.8E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS07050 1f47ad425c52fbad5d4d03914250a249 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 4.8E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS07050 1f47ad425c52fbad5d4d03914250a249 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 94 105 4.8E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS07050 1f47ad425c52fbad5d4d03914250a249 277 Pfam PF00106 short chain dehydrogenase 7 207 3.0E-50 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS07050 1f47ad425c52fbad5d4d03914250a249 277 Gene3D G3DSA:3.40.50.720 3 273 1.5E-75 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS07050 1f47ad425c52fbad5d4d03914250a249 277 SUPERFAMILY SSF51735 3 273 2.0E-70 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS07050 1f47ad425c52fbad5d4d03914250a249 277 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 154 182 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK77_RS14590 43a54e36a6066b8b29ce990221a7a05d 902 Gene3D G3DSA:3.30.365.10 323 428 2.8E-29 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK77_RS14590 43a54e36a6066b8b29ce990221a7a05d 902 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 2 49 4.6E-5 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK77_RS14590 43a54e36a6066b8b29ce990221a7a05d 902 SUPERFAMILY SSF54665 150 287 1.83E-31 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK77_RS14590 43a54e36a6066b8b29ce990221a7a05d 902 SUPERFAMILY SSF54292 2 73 2.62E-16 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK77_RS14590 43a54e36a6066b8b29ce990221a7a05d 902 Gene3D G3DSA:3.10.20.30 1 68 3.8E-19 T 06-07-2017 IPR012675 Beta-grasp domain CAK77_RS14590 43a54e36a6066b8b29ce990221a7a05d 902 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 156 268 2.4E-21 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK77_RS14590 43a54e36a6066b8b29ce990221a7a05d 902 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 303 834 1.0E-137 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK77_RS14590 43a54e36a6066b8b29ce990221a7a05d 902 SUPERFAMILY SSF56003 260 895 2.88E-161 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK77_RS14590 43a54e36a6066b8b29ce990221a7a05d 902 Pfam PF01799 [2Fe-2S] binding domain 68 136 5.9E-25 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAK77_RS14590 43a54e36a6066b8b29ce990221a7a05d 902 Gene3D G3DSA:3.90.1170.50 149 256 9.2E-30 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK77_RS14590 43a54e36a6066b8b29ce990221a7a05d 902 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 34 42 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CAK77_RS14590 43a54e36a6066b8b29ce990221a7a05d 902 Gene3D G3DSA:3.30.365.10 604 745 8.1E-31 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK77_RS14590 43a54e36a6066b8b29ce990221a7a05d 902 SMART SM01008 156 268 3.9E-32 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAK77_RS14590 43a54e36a6066b8b29ce990221a7a05d 902 Gene3D G3DSA:3.30.365.10 750 895 7.6E-50 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK77_RS14590 43a54e36a6066b8b29ce990221a7a05d 902 Gene3D G3DSA:3.30.365.10 508 603 7.6E-50 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK77_RS14590 43a54e36a6066b8b29ce990221a7a05d 902 Gene3D G3DSA:3.30.365.10 257 322 3.3E-35 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK77_RS14590 43a54e36a6066b8b29ce990221a7a05d 902 Gene3D G3DSA:3.30.365.10 431 505 3.3E-35 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAK77_RS14590 43a54e36a6066b8b29ce990221a7a05d 902 Gene3D G3DSA:1.10.150.120 69 141 1.0E-24 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAK77_RS14590 43a54e36a6066b8b29ce990221a7a05d 902 SUPERFAMILY SSF47741 76 141 3.53E-24 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAK77_RS21470 40a776f57af9002a028b3a25e00a60a8 394 Pfam PF00684 DnaJ central domain 176 236 1.2E-11 T 06-07-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 CAK77_RS21470 40a776f57af9002a028b3a25e00a60a8 394 SUPERFAMILY SSF57938 163 239 4.58E-18 T 06-07-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 CAK77_RS21470 40a776f57af9002a028b3a25e00a60a8 394 PRINTS PR00625 DnaJ domain signature 12 30 1.8E-16 T 06-07-2017 IPR001623 DnaJ domain CAK77_RS21470 40a776f57af9002a028b3a25e00a60a8 394 PRINTS PR00625 DnaJ domain signature 67 86 1.8E-16 T 06-07-2017 IPR001623 DnaJ domain CAK77_RS21470 40a776f57af9002a028b3a25e00a60a8 394 PRINTS PR00625 DnaJ domain signature 30 45 1.8E-16 T 06-07-2017 IPR001623 DnaJ domain CAK77_RS21470 40a776f57af9002a028b3a25e00a60a8 394 PRINTS PR00625 DnaJ domain signature 47 67 1.8E-16 T 06-07-2017 IPR001623 DnaJ domain CAK77_RS21470 40a776f57af9002a028b3a25e00a60a8 394 Gene3D G3DSA:1.10.287.110 3 98 8.8E-25 T 06-07-2017 IPR001623 DnaJ domain CAK77_RS21470 40a776f57af9002a028b3a25e00a60a8 394 SUPERFAMILY SSF49493 242 295 1.44E-20 T 06-07-2017 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CAK77_RS21470 40a776f57af9002a028b3a25e00a60a8 394 SUPERFAMILY SSF49493 142 181 1.44E-20 T 06-07-2017 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CAK77_RS21470 40a776f57af9002a028b3a25e00a60a8 394 SUPERFAMILY SSF49493 287 368 6.67E-21 T 06-07-2017 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CAK77_RS21470 40a776f57af9002a028b3a25e00a60a8 394 Pfam PF01556 DnaJ C terminal domain 150 361 3.9E-39 T 06-07-2017 IPR002939 Chaperone DnaJ, C-terminal CAK77_RS21470 40a776f57af9002a028b3a25e00a60a8 394 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 10 376 1.2E-118 T 06-07-2017 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 CAK77_RS21470 40a776f57af9002a028b3a25e00a60a8 394 Pfam PF00226 DnaJ domain 10 72 5.4E-21 T 06-07-2017 IPR001623 DnaJ domain CAK77_RS21470 40a776f57af9002a028b3a25e00a60a8 394 Gene3D G3DSA:2.60.260.20 239 283 7.4E-22 T 06-07-2017 CAK77_RS21470 40a776f57af9002a028b3a25e00a60a8 394 Gene3D G3DSA:2.60.260.20 119 170 7.4E-22 T 06-07-2017 CAK77_RS21470 40a776f57af9002a028b3a25e00a60a8 394 Gene3D G3DSA:2.60.260.20 286 361 3.3E-22 T 06-07-2017 CAK77_RS21470 40a776f57af9002a028b3a25e00a60a8 394 Gene3D G3DSA:2.10.230.10 171 238 4.4E-21 T 06-07-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 CAK77_RS21470 40a776f57af9002a028b3a25e00a60a8 394 SUPERFAMILY SSF46565 8 100 3.14E-24 T 06-07-2017 IPR001623 DnaJ domain CAK77_RS21470 40a776f57af9002a028b3a25e00a60a8 394 SMART SM00271 9 67 6.0E-21 T 06-07-2017 IPR001623 DnaJ domain CAK77_RS21470 40a776f57af9002a028b3a25e00a60a8 394 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 7 388 36.605 T 06-07-2017 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 CAK77_RS12775 0f2011bdd4d9bf10b292ec999ef0f505 148 SUPERFAMILY SSF54427 3 129 7.68E-24 T 06-07-2017 IPR032710 NTF2-like domain CAK77_RS12775 0f2011bdd4d9bf10b292ec999ef0f505 148 Pfam PF12680 SnoaL-like domain 14 112 9.5E-10 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain CAK77_RS12775 0f2011bdd4d9bf10b292ec999ef0f505 148 Gene3D G3DSA:3.10.450.50 5 128 2.2E-26 T 06-07-2017 IPR032710 NTF2-like domain CAK77_RS08610 9f8d80b5379ada5924a04675eb225636 312 SUPERFAMILY SSF52540 8 231 5.73E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS08610 9f8d80b5379ada5924a04675eb225636 312 Pfam PF00005 ABC transporter 28 169 3.3E-23 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK77_RS08610 9f8d80b5379ada5924a04675eb225636 312 SMART SM00382 36 225 2.8E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS08610 9f8d80b5379ada5924a04675eb225636 312 Gene3D G3DSA:3.40.50.300 6 238 2.1E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS08610 9f8d80b5379ada5924a04675eb225636 312 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK77_RS04115 b7ef7ba99dfbda061fdc7147a72986d5 230 Pfam PF12697 Alpha/beta hydrolase family 7 220 9.6E-19 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS04115 b7ef7ba99dfbda061fdc7147a72986d5 230 SUPERFAMILY SSF53474 2 224 3.46E-29 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS04115 b7ef7ba99dfbda061fdc7147a72986d5 230 Gene3D G3DSA:3.40.50.1820 3 226 6.0E-33 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS02920 4620120fa76aee605b973606e0daf756 361 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 25 137 3.2E-25 T 06-07-2017 IPR003390 DNA integrity scanning protein, DisA, N-terminal CAK77_RS02920 4620120fa76aee605b973606e0daf756 361 Gene3D G3DSA:3.40.1700.10 19 142 8.9E-32 T 06-07-2017 CAK77_RS02920 4620120fa76aee605b973606e0daf756 361 Gene3D G3DSA:1.10.150.20 309 348 2.2E-8 T 06-07-2017 CAK77_RS02920 4620120fa76aee605b973606e0daf756 361 SUPERFAMILY SSF47781 284 348 6.35E-11 T 06-07-2017 IPR010994 RuvA domain 2-like CAK77_RS02920 4620120fa76aee605b973606e0daf756 361 SUPERFAMILY SSF143597 17 143 1.44E-28 T 06-07-2017 CAK77_RS02920 4620120fa76aee605b973606e0daf756 361 Pfam PF10635 DisA bacterial checkpoint controller linker region 144 285 2.9E-47 T 06-07-2017 IPR018906 DNA integrity scanning, DisA, linker region CAK77_RS02920 4620120fa76aee605b973606e0daf756 361 Hamap MF_01438 DNA integrity scanning protein DisA [disA]. 4 358 42.495 T 06-07-2017 IPR023763 DNA integrity scanning protein, DisA CAK77_RS07235 51c2a5c1924d23baea801521382d44b5 356 Pfam PF03462 PCRF domain 12 203 3.4E-62 T 06-07-2017 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 CAK77_RS07235 51c2a5c1924d23baea801521382d44b5 356 SMART SM00937 65 178 1.6E-46 T 06-07-2017 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 CAK77_RS07235 51c2a5c1924d23baea801521382d44b5 356 Gene3D G3DSA:3.30.160.20 213 288 3.7E-35 T 06-07-2017 IPR014720 Double-stranded RNA-binding domain CAK77_RS07235 51c2a5c1924d23baea801521382d44b5 356 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 7 355 5.4E-150 T 06-07-2017 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 CAK77_RS07235 51c2a5c1924d23baea801521382d44b5 356 Pfam PF00472 RF-1 domain 213 321 4.5E-41 T 06-07-2017 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CAK77_RS07235 51c2a5c1924d23baea801521382d44b5 356 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 228 244 - T 06-07-2017 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CAK77_RS07235 51c2a5c1924d23baea801521382d44b5 356 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 3 356 35.522 T 06-07-2017 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 CAK77_RS07235 51c2a5c1924d23baea801521382d44b5 356 Gene3D G3DSA:1.20.58.410 7 92 8.3E-14 T 06-07-2017 CAK77_RS07235 51c2a5c1924d23baea801521382d44b5 356 SUPERFAMILY SSF75620 10 353 1.19E-122 T 06-07-2017 CAK77_RS12150 6ba512f573d5272cfc3c10af90c209aa 333 PRINTS PR00412 Epoxide hydrolase signature 151 164 4.0E-15 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK77_RS12150 6ba512f573d5272cfc3c10af90c209aa 333 PRINTS PR00412 Epoxide hydrolase signature 308 330 4.0E-15 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK77_RS12150 6ba512f573d5272cfc3c10af90c209aa 333 PRINTS PR00412 Epoxide hydrolase signature 137 150 4.0E-15 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK77_RS12150 6ba512f573d5272cfc3c10af90c209aa 333 PRINTS PR00412 Epoxide hydrolase signature 89 104 4.0E-15 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK77_RS12150 6ba512f573d5272cfc3c10af90c209aa 333 PRINTS PR00412 Epoxide hydrolase signature 69 87 4.0E-15 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK77_RS12150 6ba512f573d5272cfc3c10af90c209aa 333 Gene3D G3DSA:3.40.50.1820 38 328 3.2E-47 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS12150 6ba512f573d5272cfc3c10af90c209aa 333 SUPERFAMILY SSF53474 40 329 7.31E-56 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS12150 6ba512f573d5272cfc3c10af90c209aa 333 Pfam PF00561 alpha/beta hydrolase fold 63 194 6.0E-16 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS02305 c10acd0ec632fbf1cce2228a6c9e6e35 224 Gene3D G3DSA:1.10.10.10 144 223 9.1E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS02305 c10acd0ec632fbf1cce2228a6c9e6e35 224 SUPERFAMILY SSF46785 145 223 2.04E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS02305 c10acd0ec632fbf1cce2228a6c9e6e35 224 Pfam PF00027 Cyclic nucleotide-binding domain 29 114 2.8E-23 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain CAK77_RS02305 c10acd0ec632fbf1cce2228a6c9e6e35 224 Pfam PF13545 Crp-like helix-turn-helix domain 148 221 1.4E-17 T 06-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CAK77_RS02305 c10acd0ec632fbf1cce2228a6c9e6e35 224 Gene3D G3DSA:2.60.120.10 2 142 7.1E-38 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK77_RS02305 c10acd0ec632fbf1cce2228a6c9e6e35 224 SMART SM00100 10 128 1.2E-27 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain CAK77_RS02305 c10acd0ec632fbf1cce2228a6c9e6e35 224 SUPERFAMILY SSF51206 4 142 1.83E-36 T 06-07-2017 IPR018490 Cyclic nucleotide-binding-like CAK77_RS02305 c10acd0ec632fbf1cce2228a6c9e6e35 224 SMART SM00419 167 215 1.2E-13 T 06-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CAK77_RS02350 44cbbee1f6fbbc47ac9b6aa38840e5e3 658 Gene3D G3DSA:3.40.50.980 273 431 3.4E-26 T 06-07-2017 CAK77_RS02350 44cbbee1f6fbbc47ac9b6aa38840e5e3 658 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 20 656 1.9E-285 T 06-07-2017 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118|Reactome: R-HSA-71384 CAK77_RS02350 44cbbee1f6fbbc47ac9b6aa38840e5e3 658 SUPERFAMILY SSF56801 18 656 3.01E-175 T 06-07-2017 CAK77_RS02350 44cbbee1f6fbbc47ac9b6aa38840e5e3 658 ProSitePatterns PS00455 Putative AMP-binding domain signature. 267 278 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK77_RS02350 44cbbee1f6fbbc47ac9b6aa38840e5e3 658 Gene3D G3DSA:2.30.38.10 446 530 4.5E-12 T 06-07-2017 CAK77_RS02350 44cbbee1f6fbbc47ac9b6aa38840e5e3 658 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 26 78 8.3E-22 T 06-07-2017 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118 CAK77_RS02350 44cbbee1f6fbbc47ac9b6aa38840e5e3 658 Gene3D G3DSA:3.40.50.980 76 272 4.2E-41 T 06-07-2017 CAK77_RS02350 44cbbee1f6fbbc47ac9b6aa38840e5e3 658 Pfam PF00501 AMP-binding enzyme 85 536 2.2E-96 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK77_RS02350 44cbbee1f6fbbc47ac9b6aa38840e5e3 658 Pfam PF13193 AMP-binding enzyme C-terminal domain 545 624 9.5E-27 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAK77_RS02350 44cbbee1f6fbbc47ac9b6aa38840e5e3 658 Gene3D G3DSA:3.30.300.30 534 638 1.9E-28 T 06-07-2017 CAK77_RS02350 44cbbee1f6fbbc47ac9b6aa38840e5e3 658 Hamap MF_01123 Acetyl-coenzyme A synthetase [acs]. 6 658 49.714 T 06-07-2017 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118|Reactome: R-HSA-71384 CAK77_RS23555 809dd83090a0393bd9cd5d36897c397d 294 SUPERFAMILY SSF53850 87 281 1.85E-27 T 06-07-2017 CAK77_RS23555 809dd83090a0393bd9cd5d36897c397d 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 9.9E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK77_RS23555 809dd83090a0393bd9cd5d36897c397d 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 9.9E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK77_RS23555 809dd83090a0393bd9cd5d36897c397d 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 9.9E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK77_RS23555 809dd83090a0393bd9cd5d36897c397d 294 Gene3D G3DSA:3.40.190.10 85 186 6.7E-16 T 06-07-2017 CAK77_RS23555 809dd83090a0393bd9cd5d36897c397d 294 Gene3D G3DSA:3.40.190.10 187 234 7.5E-6 T 06-07-2017 CAK77_RS23555 809dd83090a0393bd9cd5d36897c397d 294 Gene3D G3DSA:1.10.10.10 3 80 2.8E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS23555 809dd83090a0393bd9cd5d36897c397d 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 5.4E-17 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK77_RS23555 809dd83090a0393bd9cd5d36897c397d 294 SUPERFAMILY SSF46785 2 109 1.93E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS23555 809dd83090a0393bd9cd5d36897c397d 294 Pfam PF03466 LysR substrate binding domain 86 275 9.9E-26 T 06-07-2017 IPR005119 LysR, substrate-binding CAK77_RS05140 982be4d50cb828d046f5ca634aa834e2 157 Gene3D G3DSA:1.10.10.10 7 146 3.9E-33 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS05140 982be4d50cb828d046f5ca634aa834e2 157 SMART SM00347 34 134 1.6E-24 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK77_RS05140 982be4d50cb828d046f5ca634aa834e2 157 SUPERFAMILY SSF46785 4 146 2.19E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS05140 982be4d50cb828d046f5ca634aa834e2 157 Pfam PF01047 MarR family 41 98 6.2E-17 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK77_RS06905 15b6f3cc1e0c0887e3d580ae7bea62b7 213 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 65 4.8E-18 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS06905 15b6f3cc1e0c0887e3d580ae7bea62b7 213 SUPERFAMILY SSF48498 102 204 9.69E-14 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS06905 15b6f3cc1e0c0887e3d580ae7bea62b7 213 SUPERFAMILY SSF46689 7 80 4.94E-21 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS06905 15b6f3cc1e0c0887e3d580ae7bea62b7 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 2.7E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS06905 15b6f3cc1e0c0887e3d580ae7bea62b7 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 2.7E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS06905 15b6f3cc1e0c0887e3d580ae7bea62b7 213 Gene3D G3DSA:1.10.10.60 9 65 1.4E-23 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS06905 15b6f3cc1e0c0887e3d580ae7bea62b7 213 Gene3D G3DSA:1.10.357.10 66 205 2.2E-19 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS15220 89412cd5ec726f06655fd6871ab6096c 172 Pfam PF11706 CGNR zinc finger 128 170 1.3E-20 T 06-07-2017 IPR021005 Zinc finger, CGNR CAK77_RS15220 89412cd5ec726f06655fd6871ab6096c 172 Gene3D G3DSA:1.10.3300.10 3 170 7.1E-43 T 06-07-2017 IPR023286 ABATE domain CAK77_RS15220 89412cd5ec726f06655fd6871ab6096c 172 Pfam PF07336 Putative stress-induced transcription regulator 11 123 4.4E-12 T 06-07-2017 IPR010852 Putative stress-induced transcription regulator CAK77_RS15220 89412cd5ec726f06655fd6871ab6096c 172 SUPERFAMILY SSF160904 3 170 6.28E-43 T 06-07-2017 CAK77_RS05640 c9a813e0c0de8e3c6ea71ac78e68bf7d 314 SUPERFAMILY SSF55060 176 295 3.6E-20 T 06-07-2017 IPR013750 GHMP kinase, C-terminal domain CAK77_RS05640 c9a813e0c0de8e3c6ea71ac78e68bf7d 314 Hamap MF_00061 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 14 300 30.735 T 06-07-2017 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 CAK77_RS05640 c9a813e0c0de8e3c6ea71ac78e68bf7d 314 SUPERFAMILY SSF54211 14 167 3.34E-42 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAK77_RS05640 c9a813e0c0de8e3c6ea71ac78e68bf7d 314 PIRSF PIRSF010376 12 309 6.2E-81 T 06-07-2017 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 CAK77_RS05640 c9a813e0c0de8e3c6ea71ac78e68bf7d 314 Gene3D G3DSA:3.30.230.10 14 169 5.8E-52 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CAK77_RS05640 c9a813e0c0de8e3c6ea71ac78e68bf7d 314 Pfam PF08544 GHMP kinases C terminal 215 287 5.2E-11 T 06-07-2017 IPR013750 GHMP kinase, C-terminal domain CAK77_RS05640 c9a813e0c0de8e3c6ea71ac78e68bf7d 314 Pfam PF00288 GHMP kinases N terminal domain 99 156 5.7E-8 T 06-07-2017 IPR006204 GHMP kinase N-terminal domain GO:0005524 CAK77_RS05640 c9a813e0c0de8e3c6ea71ac78e68bf7d 314 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 15 284 9.3E-51 T 06-07-2017 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 CAK77_RS05640 c9a813e0c0de8e3c6ea71ac78e68bf7d 314 Gene3D G3DSA:3.30.70.890 176 292 3.0E-23 T 06-07-2017 IPR013750 GHMP kinase, C-terminal domain CAK77_RS06640 ee9ba1ce10c042e897016f81a5853319 102 Pfam PF03992 Antibiotic biosynthesis monooxygenase 5 80 1.4E-11 T 06-07-2017 IPR007138 Antibiotic biosynthesis monooxygenase domain CAK77_RS06640 ee9ba1ce10c042e897016f81a5853319 102 Gene3D G3DSA:3.30.70.900 2 99 6.0E-30 T 06-07-2017 CAK77_RS06640 ee9ba1ce10c042e897016f81a5853319 102 SUPERFAMILY SSF54909 4 99 4.03E-19 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAK77_RS11095 e477ca53232d648227d9714d3aee5fb3 178 SMART SM00903 27 170 1.3E-30 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 CAK77_RS11095 e477ca53232d648227d9714d3aee5fb3 178 Gene3D G3DSA:2.30.110.10 19 168 1.2E-37 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS11095 e477ca53232d648227d9714d3aee5fb3 178 Pfam PF01613 Flavin reductase like domain 28 170 9.1E-27 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 CAK77_RS11095 e477ca53232d648227d9714d3aee5fb3 178 SUPERFAMILY SSF50475 21 174 9.32E-34 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS23265 7f36b40dff954b15ddc4a4946c0118b1 133 Pfam PF01592 NifU-like N terminal domain 5 121 2.3E-26 T 06-07-2017 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 CAK77_RS23265 7f36b40dff954b15ddc4a4946c0118b1 133 SUPERFAMILY SSF82649 8 121 1.07E-27 T 06-07-2017 CAK77_RS23265 7f36b40dff954b15ddc4a4946c0118b1 133 Gene3D G3DSA:3.90.1010.10 5 122 2.9E-25 T 06-07-2017 CAK77_RS10705 00a45972a1fbb8e39db39f9dbec00f9b 499 TIGRFAM TIGR01467 cobI_cbiL: precorrin-2 C(20)-methyltransferase 10 241 7.8E-67 T 06-07-2017 IPR006364 Precorrin-2 C(20)-methyltransferase domain GO:0008757|GO:0009236 CAK77_RS10705 00a45972a1fbb8e39db39f9dbec00f9b 499 TIGRFAM TIGR01466 cobJ_cbiH: precorrin-3B C17-methyltransferase 257 496 5.9E-81 T 06-07-2017 IPR006363 Precorrin-3B C17-methyltransferase domain GO:0008168|GO:0009236 CAK77_RS10705 00a45972a1fbb8e39db39f9dbec00f9b 499 SUPERFAMILY SSF53790 253 483 2.22E-47 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAK77_RS10705 00a45972a1fbb8e39db39f9dbec00f9b 499 Gene3D G3DSA:3.30.950.10 366 478 5.9E-11 T 06-07-2017 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAK77_RS10705 00a45972a1fbb8e39db39f9dbec00f9b 499 Gene3D G3DSA:3.40.1010.10 255 365 4.0E-25 T 06-07-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAK77_RS10705 00a45972a1fbb8e39db39f9dbec00f9b 499 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 107 139 - T 06-07-2017 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CAK77_RS10705 00a45972a1fbb8e39db39f9dbec00f9b 499 SUPERFAMILY SSF53790 4 246 5.1E-47 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAK77_RS10705 00a45972a1fbb8e39db39f9dbec00f9b 499 Gene3D G3DSA:3.40.1010.10 9 140 2.8E-32 T 06-07-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAK77_RS10705 00a45972a1fbb8e39db39f9dbec00f9b 499 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 14 28 - T 06-07-2017 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CAK77_RS10705 00a45972a1fbb8e39db39f9dbec00f9b 499 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 11 223 1.0E-45 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAK77_RS10705 00a45972a1fbb8e39db39f9dbec00f9b 499 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 256 462 7.5E-34 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAK77_RS12650 20fa39b67049168cf5d4efa5039f201f 121 Gene3D G3DSA:1.10.260.40 37 77 1.7E-4 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK77_RS12650 20fa39b67049168cf5d4efa5039f201f 121 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 12 77 2.0E-18 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAK77_RS04015 21bff2261cf27e6ed6bdd6b4292a137b 302 SUPERFAMILY SSF161098 36 290 1.85E-38 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS04015 21bff2261cf27e6ed6bdd6b4292a137b 302 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 99 300 2.3E-28 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS04015 21bff2261cf27e6ed6bdd6b4292a137b 302 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 26 297 2.1E-80 T 06-07-2017 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 CAK77_RS04015 21bff2261cf27e6ed6bdd6b4292a137b 302 Gene3D G3DSA:1.10.3720.10 28 297 1.5E-43 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS16690 aef0da66f2b05e6527f9ff7f2dc5a63e 356 Gene3D G3DSA:3.40.50.620 2 204 2.0E-76 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS16690 aef0da66f2b05e6527f9ff7f2dc5a63e 356 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 2 353 2.5E-86 T 06-07-2017 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 CAK77_RS16690 aef0da66f2b05e6527f9ff7f2dc5a63e 356 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 1 354 36.678 T 06-07-2017 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 CAK77_RS16690 aef0da66f2b05e6527f9ff7f2dc5a63e 356 SUPERFAMILY SSF52402 2 238 4.85E-47 T 06-07-2017 CAK77_RS16690 aef0da66f2b05e6527f9ff7f2dc5a63e 356 Gene3D G3DSA:2.40.30.10 280 355 1.9E-17 T 06-07-2017 CAK77_RS16690 aef0da66f2b05e6527f9ff7f2dc5a63e 356 Pfam PF03054 tRNA methyl transferase 2 353 3.8E-114 T 06-07-2017 CAK77_RS16690 aef0da66f2b05e6527f9ff7f2dc5a63e 356 Gene3D G3DSA:2.30.30.280 210 269 5.3E-15 T 06-07-2017 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 Reactome: R-HSA-6787450 CAK77_RS13675 5bb7070e1c5c9dec8e326ac8861432ff 197 PIRSF PIRSF000498 1 197 6.1E-70 T 06-07-2017 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CAK77_RS13675 5bb7070e1c5c9dec8e326ac8861432ff 197 SUPERFAMILY SSF63380 1 88 1.7E-22 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CAK77_RS13675 5bb7070e1c5c9dec8e326ac8861432ff 197 Gene3D G3DSA:2.40.30.20 105 196 2.3E-31 T 06-07-2017 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 CAK77_RS13675 5bb7070e1c5c9dec8e326ac8861432ff 197 Gene3D G3DSA:2.40.30.20 5 104 4.9E-30 T 06-07-2017 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 CAK77_RS13675 5bb7070e1c5c9dec8e326ac8861432ff 197 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 195 1.4E-62 T 06-07-2017 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CAK77_RS13675 5bb7070e1c5c9dec8e326ac8861432ff 197 SUPERFAMILY SSF63380 93 195 4.0E-33 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CAK77_RS13675 5bb7070e1c5c9dec8e326ac8861432ff 197 Pfam PF00677 Lumazine binding domain 100 184 3.2E-22 T 06-07-2017 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CAK77_RS13675 5bb7070e1c5c9dec8e326ac8861432ff 197 Pfam PF00677 Lumazine binding domain 3 87 1.3E-20 T 06-07-2017 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CAK77_RS18470 a06c1008081a0c114507977468618a58 670 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 489 505 4.1E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS18470 a06c1008081a0c114507977468618a58 670 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 440 451 4.1E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS18470 a06c1008081a0c114507977468618a58 670 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 366 383 4.1E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS18470 a06c1008081a0c114507977468618a58 670 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 515 534 4.1E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS18470 a06c1008081a0c114507977468618a58 670 Pfam PF00106 short chain dehydrogenase 366 555 5.7E-45 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS18470 a06c1008081a0c114507977468618a58 670 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 495 503 6.8E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS18470 a06c1008081a0c114507977468618a58 670 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 440 451 6.8E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS18470 a06c1008081a0c114507977468618a58 670 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 515 534 6.8E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS18470 a06c1008081a0c114507977468618a58 670 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 365 549 0.0027 T 06-07-2017 CAK77_RS18470 a06c1008081a0c114507977468618a58 670 Gene3D G3DSA:3.40.50.720 2 274 2.4E-41 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS18470 a06c1008081a0c114507977468618a58 670 Pfam PF07993 Male sterility protein 5 227 9.6E-43 T 06-07-2017 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 CAK77_RS18470 a06c1008081a0c114507977468618a58 670 SUPERFAMILY SSF51735 362 585 2.03E-58 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS18470 a06c1008081a0c114507977468618a58 670 SUPERFAMILY SSF51735 3 268 8.5E-43 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS18470 a06c1008081a0c114507977468618a58 670 Gene3D G3DSA:3.40.50.720 364 610 1.2E-57 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS22590 75c4f1d538d0cc22a2a3cdb3e7afcc98 653 SMART SM00878 334 438 2.0E-44 T 06-07-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAK77_RS22590 75c4f1d538d0cc22a2a3cdb3e7afcc98 653 Gene3D G3DSA:3.30.470.20 200 441 2.8E-93 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAK77_RS22590 75c4f1d538d0cc22a2a3cdb3e7afcc98 653 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 112 320 1.4E-74 T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CAK77_RS22590 75c4f1d538d0cc22a2a3cdb3e7afcc98 653 Gene3D G3DSA:2.40.50.100 572 642 3.9E-17 T 06-07-2017 CAK77_RS22590 75c4f1d538d0cc22a2a3cdb3e7afcc98 653 SUPERFAMILY SSF51246 329 442 2.15E-33 T 06-07-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAK77_RS22590 75c4f1d538d0cc22a2a3cdb3e7afcc98 653 Gene3D G3DSA:3.30.1490.20 127 198 3.5E-22 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CAK77_RS22590 75c4f1d538d0cc22a2a3cdb3e7afcc98 653 Pfam PF00289 Biotin carboxylase, N-terminal domain 3 107 1.1E-36 T 06-07-2017 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAK77_RS22590 75c4f1d538d0cc22a2a3cdb3e7afcc98 653 SUPERFAMILY SSF51230 564 642 2.42E-15 T 06-07-2017 IPR011053 Single hybrid motif CAK77_RS22590 75c4f1d538d0cc22a2a3cdb3e7afcc98 653 Pfam PF02785 Biotin carboxylase C-terminal domain 334 438 1.1E-30 T 06-07-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAK77_RS22590 75c4f1d538d0cc22a2a3cdb3e7afcc98 653 SUPERFAMILY SSF52440 3 110 1.37E-38 T 06-07-2017 IPR016185 Pre-ATP-grasp domain CAK77_RS22590 75c4f1d538d0cc22a2a3cdb3e7afcc98 653 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 284 291 - T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CAK77_RS22590 75c4f1d538d0cc22a2a3cdb3e7afcc98 653 SUPERFAMILY SSF56059 80 346 5.66E-65 T 06-07-2017 CAK77_RS22590 75c4f1d538d0cc22a2a3cdb3e7afcc98 653 Gene3D G3DSA:3.40.50.20 3 126 5.3E-44 T 06-07-2017 IPR016185 Pre-ATP-grasp domain CAK77_RS22590 75c4f1d538d0cc22a2a3cdb3e7afcc98 653 Pfam PF00364 Biotin-requiring enzyme 577 642 3.9E-10 T 06-07-2017 IPR000089 Biotin/lipoyl attachment CAK77_RS14710 d15f6d5722e0dda6055c14921d7f3c80 501 Gene3D G3DSA:1.20.1250.20 473 497 6.4E-15 T 06-07-2017 CAK77_RS14710 d15f6d5722e0dda6055c14921d7f3c80 501 Gene3D G3DSA:1.20.1250.20 276 433 6.4E-15 T 06-07-2017 CAK77_RS14710 d15f6d5722e0dda6055c14921d7f3c80 501 SUPERFAMILY SSF103473 6 214 5.1E-61 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK77_RS14710 d15f6d5722e0dda6055c14921d7f3c80 501 SUPERFAMILY SSF103473 468 500 5.1E-61 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK77_RS14710 d15f6d5722e0dda6055c14921d7f3c80 501 SUPERFAMILY SSF103473 261 432 5.1E-61 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK77_RS14710 d15f6d5722e0dda6055c14921d7f3c80 501 PRINTS PR01036 Tetracycline resistance protein TetB signature 152 176 1.2E-7 T 06-07-2017 CAK77_RS14710 d15f6d5722e0dda6055c14921d7f3c80 501 PRINTS PR01036 Tetracycline resistance protein TetB signature 217 235 1.2E-7 T 06-07-2017 CAK77_RS14710 d15f6d5722e0dda6055c14921d7f3c80 501 PRINTS PR01036 Tetracycline resistance protein TetB signature 90 112 1.2E-7 T 06-07-2017 CAK77_RS14710 d15f6d5722e0dda6055c14921d7f3c80 501 PRINTS PR01036 Tetracycline resistance protein TetB signature 413 432 1.2E-7 T 06-07-2017 CAK77_RS14710 d15f6d5722e0dda6055c14921d7f3c80 501 Pfam PF07690 Major Facilitator Superfamily 338 432 7.9E-10 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK77_RS14710 d15f6d5722e0dda6055c14921d7f3c80 501 Pfam PF07690 Major Facilitator Superfamily 35 328 3.6E-37 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK77_RS14710 d15f6d5722e0dda6055c14921d7f3c80 501 Gene3D G3DSA:1.20.1250.20 23 209 1.5E-27 T 06-07-2017 CAK77_RS07210 eae800c64fc13faf8c414f7405d269bb 644 Hamap MF_01884 Transcription termination factor Rho [rho]. 254 631 196.944 T 06-07-2017 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 CAK77_RS07210 eae800c64fc13faf8c414f7405d269bb 644 SUPERFAMILY SSF50249 262 339 7.71E-13 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS07210 eae800c64fc13faf8c414f7405d269bb 644 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 371 575 4.3E-26 T 06-07-2017 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CAK77_RS07210 eae800c64fc13faf8c414f7405d269bb 644 SUPERFAMILY SSF52540 333 582 2.29E-66 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS07210 eae800c64fc13faf8c414f7405d269bb 644 SUPERFAMILY SSF68912 37 75 1.22E-5 T 06-07-2017 IPR011112 Rho termination factor, N-terminal GO:0006353 CAK77_RS07210 eae800c64fc13faf8c414f7405d269bb 644 SMART SM00357 262 333 8.7E-4 T 06-07-2017 IPR011129 Cold shock protein GO:0003676 CAK77_RS07210 eae800c64fc13faf8c414f7405d269bb 644 Gene3D G3DSA:2.40.50.140 256 340 1.2E-37 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS07210 eae800c64fc13faf8c414f7405d269bb 644 Gene3D G3DSA:2.40.50.140 38 78 1.2E-37 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS07210 eae800c64fc13faf8c414f7405d269bb 644 SMART SM00959 38 80 1.4E-10 T 06-07-2017 IPR011112 Rho termination factor, N-terminal GO:0006353 CAK77_RS07210 eae800c64fc13faf8c414f7405d269bb 644 SMART SM00382 382 567 2.6E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS07210 eae800c64fc13faf8c414f7405d269bb 644 Pfam PF07498 Rho termination factor, N-terminal domain 39 75 1.5E-10 T 06-07-2017 IPR011112 Rho termination factor, N-terminal GO:0006353 CAK77_RS07210 eae800c64fc13faf8c414f7405d269bb 644 Pfam PF07497 Rho termination factor, RNA-binding domain 261 340 1.5E-27 T 06-07-2017 IPR011113 Rho termination factor, RNA-binding GO:0003723|GO:0006353 CAK77_RS07210 eae800c64fc13faf8c414f7405d269bb 644 Gene3D G3DSA:3.40.50.300 346 629 1.1E-96 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS07210 eae800c64fc13faf8c414f7405d269bb 644 TIGRFAM TIGR00767 rho: transcription termination factor Rho 38 630 2.1E-206 T 06-07-2017 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 CAK77_RS07865 72364bac2048fa3ae112da01e1e55281 160 PIRSF PIRSF002070 1 154 4.7E-27 T 06-07-2017 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 CAK77_RS07865 72364bac2048fa3ae112da01e1e55281 160 SUPERFAMILY SSF50249 6 133 2.4E-25 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS07865 72364bac2048fa3ae112da01e1e55281 160 Gene3D G3DSA:2.40.50.140 4 110 4.8E-26 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS07865 72364bac2048fa3ae112da01e1e55281 160 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 6 134 1.6E-16 T 06-07-2017 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 CAK77_RS07865 72364bac2048fa3ae112da01e1e55281 160 Pfam PF00436 Single-strand binding protein family 6 100 5.4E-17 T 06-07-2017 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 CAK77_RS19630 03b5f6f09f3a5045feaffee6c2af737e 287 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK77_RS19630 03b5f6f09f3a5045feaffee6c2af737e 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 7.3E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS19630 03b5f6f09f3a5045feaffee6c2af737e 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 7.3E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS19630 03b5f6f09f3a5045feaffee6c2af737e 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 7.3E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS19630 03b5f6f09f3a5045feaffee6c2af737e 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 7.3E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS19630 03b5f6f09f3a5045feaffee6c2af737e 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 7.3E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS19630 03b5f6f09f3a5045feaffee6c2af737e 287 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 193 8.2E-5 T 06-07-2017 CAK77_RS19630 03b5f6f09f3a5045feaffee6c2af737e 287 Gene3D G3DSA:3.40.50.720 6 239 1.9E-69 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS19630 03b5f6f09f3a5045feaffee6c2af737e 287 Pfam PF00106 short chain dehydrogenase 7 198 1.2E-52 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS19630 03b5f6f09f3a5045feaffee6c2af737e 287 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 3.8E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS19630 03b5f6f09f3a5045feaffee6c2af737e 287 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 3.8E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS19630 03b5f6f09f3a5045feaffee6c2af737e 287 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 3.8E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS19630 03b5f6f09f3a5045feaffee6c2af737e 287 SUPERFAMILY SSF51735 1 267 1.5E-69 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS07145 9989d146d66d5cd102ddbf6c6b2fe2a7 519 SUPERFAMILY SSF48264 57 517 3.14E-98 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS07145 9989d146d66d5cd102ddbf6c6b2fe2a7 519 PRINTS PR00385 P450 superfamily signature 456 465 8.2E-13 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS07145 9989d146d66d5cd102ddbf6c6b2fe2a7 519 PRINTS PR00385 P450 superfamily signature 465 476 8.2E-13 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS07145 9989d146d66d5cd102ddbf6c6b2fe2a7 519 PRINTS PR00385 P450 superfamily signature 329 346 8.2E-13 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS07145 9989d146d66d5cd102ddbf6c6b2fe2a7 519 PRINTS PR00385 P450 superfamily signature 381 392 8.2E-13 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS07145 9989d146d66d5cd102ddbf6c6b2fe2a7 519 Pfam PF00067 Cytochrome P450 80 225 1.5E-11 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS07145 9989d146d66d5cd102ddbf6c6b2fe2a7 519 Pfam PF00067 Cytochrome P450 276 499 9.9E-63 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS07145 9989d146d66d5cd102ddbf6c6b2fe2a7 519 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 458 467 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CAK77_RS07145 9989d146d66d5cd102ddbf6c6b2fe2a7 519 PRINTS PR00463 E-class P450 group I signature 318 335 1.6E-22 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS07145 9989d146d66d5cd102ddbf6c6b2fe2a7 519 PRINTS PR00463 E-class P450 group I signature 455 465 1.6E-22 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS07145 9989d146d66d5cd102ddbf6c6b2fe2a7 519 PRINTS PR00463 E-class P450 group I signature 338 364 1.6E-22 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS07145 9989d146d66d5cd102ddbf6c6b2fe2a7 519 PRINTS PR00463 E-class P450 group I signature 420 444 1.6E-22 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS07145 9989d146d66d5cd102ddbf6c6b2fe2a7 519 PRINTS PR00463 E-class P450 group I signature 465 488 1.6E-22 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS07145 9989d146d66d5cd102ddbf6c6b2fe2a7 519 Gene3D G3DSA:1.10.630.10 48 517 1.0E-108 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS02815 c6a5d848b5c5c14186f53a744b72980b 310 SUPERFAMILY SSF52374 16 293 1.66E-102 T 06-07-2017 CAK77_RS02815 c6a5d848b5c5c14186f53a744b72980b 310 Pfam PF02569 Pantoate-beta-alanine ligase 21 290 4.9E-95 T 06-07-2017 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 CAK77_RS02815 c6a5d848b5c5c14186f53a744b72980b 310 Gene3D G3DSA:3.30.1300.10 193 295 6.7E-31 T 06-07-2017 CAK77_RS02815 c6a5d848b5c5c14186f53a744b72980b 310 Hamap MF_00158 Pantothenate synthetase [panC]. 19 292 38.257 T 06-07-2017 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 CAK77_RS02815 c6a5d848b5c5c14186f53a744b72980b 310 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 25 292 1.1E-85 T 06-07-2017 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 CAK77_RS02815 c6a5d848b5c5c14186f53a744b72980b 310 Gene3D G3DSA:3.40.50.620 17 192 2.4E-78 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS20730 6081a7af3b443fc3a784e1927ab36ba0 509 Gene3D G3DSA:3.40.309.10 259 447 9.7E-68 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAK77_RS20730 6081a7af3b443fc3a784e1927ab36ba0 509 Pfam PF00171 Aldehyde dehydrogenase family 16 467 1.3E-137 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAK77_RS20730 6081a7af3b443fc3a784e1927ab36ba0 509 Gene3D G3DSA:3.40.605.10 10 258 1.0E-69 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAK77_RS20730 6081a7af3b443fc3a784e1927ab36ba0 509 SUPERFAMILY SSF53720 10 468 1.02E-140 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAK77_RS20730 6081a7af3b443fc3a784e1927ab36ba0 509 PIRSF PIRSF036492 29 501 5.6E-87 T 06-07-2017 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0004030|GO:0006081|GO:0055114 CAK77_RS20730 6081a7af3b443fc3a784e1927ab36ba0 509 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 243 250 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CAK77_RS01770 716212d4409f79fbe21b9ebf4f027dbd 487 Pfam PF06628 Catalase-related immune-responsive 419 480 4.5E-16 T 06-07-2017 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAK77_RS01770 716212d4409f79fbe21b9ebf4f027dbd 487 SMART SM01060 6 390 2.7E-279 T 06-07-2017 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAK77_RS01770 716212d4409f79fbe21b9ebf4f027dbd 487 Pfam PF00199 Catalase 6 387 1.3E-184 T 06-07-2017 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAK77_RS01770 716212d4409f79fbe21b9ebf4f027dbd 487 SUPERFAMILY SSF56634 4 482 3.27E-195 T 06-07-2017 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAK77_RS01770 716212d4409f79fbe21b9ebf4f027dbd 487 Gene3D G3DSA:2.40.180.10 4 355 8.2E-173 T 06-07-2017 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAK77_RS01770 716212d4409f79fbe21b9ebf4f027dbd 487 PRINTS PR00067 Catalase signature 19 42 1.5E-70 T 06-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAK77_RS01770 716212d4409f79fbe21b9ebf4f027dbd 487 PRINTS PR00067 Catalase signature 102 119 1.5E-70 T 06-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAK77_RS01770 716212d4409f79fbe21b9ebf4f027dbd 487 PRINTS PR00067 Catalase signature 81 99 1.5E-70 T 06-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAK77_RS01770 716212d4409f79fbe21b9ebf4f027dbd 487 PRINTS PR00067 Catalase signature 286 313 1.5E-70 T 06-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAK77_RS01770 716212d4409f79fbe21b9ebf4f027dbd 487 PRINTS PR00067 Catalase signature 318 344 1.5E-70 T 06-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAK77_RS01770 716212d4409f79fbe21b9ebf4f027dbd 487 PRINTS PR00067 Catalase signature 121 139 1.5E-70 T 06-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAK77_RS01770 716212d4409f79fbe21b9ebf4f027dbd 487 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 331 339 - T 06-07-2017 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAK77_RS01770 716212d4409f79fbe21b9ebf4f027dbd 487 PIRSF PIRSF038928 1 485 2.7E-232 T 06-07-2017 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAK77_RS01770 716212d4409f79fbe21b9ebf4f027dbd 487 ProSitePatterns PS00438 Catalase proximal active site signature. 42 58 - T 06-07-2017 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAK77_RS02710 9a6b5f97d772411c8feaed11beefee84 465 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 353 367 3.7E-29 T 06-07-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CAK77_RS02710 9a6b5f97d772411c8feaed11beefee84 465 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 419 432 3.7E-29 T 06-07-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CAK77_RS02710 9a6b5f97d772411c8feaed11beefee84 465 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 338 352 3.7E-29 T 06-07-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CAK77_RS02710 9a6b5f97d772411c8feaed11beefee84 465 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 116 135 3.7E-29 T 06-07-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CAK77_RS02710 9a6b5f97d772411c8feaed11beefee84 465 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 281 303 3.7E-29 T 06-07-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CAK77_RS02710 9a6b5f97d772411c8feaed11beefee84 465 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 78 241 1.6E-39 T 06-07-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CAK77_RS02710 9a6b5f97d772411c8feaed11beefee84 465 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 245 456 4.0E-67 T 06-07-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CAK77_RS02710 9a6b5f97d772411c8feaed11beefee84 465 SUPERFAMILY SSF56601 89 463 3.76E-58 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK77_RS02710 9a6b5f97d772411c8feaed11beefee84 465 Gene3D G3DSA:3.40.710.10 97 149 1.4E-61 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK77_RS02710 9a6b5f97d772411c8feaed11beefee84 465 Gene3D G3DSA:3.40.710.10 276 464 1.4E-61 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK77_RS02710 9a6b5f97d772411c8feaed11beefee84 465 TIGRFAM TIGR00666 PBP4: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase 238 441 7.2E-63 T 06-07-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CAK77_RS12575 e48c214f4f7bbb206bb8053758900df8 275 Gene3D G3DSA:1.10.1660.10 64 113 1.5E-7 T 06-07-2017 CAK77_RS12575 e48c214f4f7bbb206bb8053758900df8 275 Gene3D G3DSA:1.10.1660.10 4 63 9.9E-21 T 06-07-2017 CAK77_RS12575 e48c214f4f7bbb206bb8053758900df8 275 SUPERFAMILY SSF55136 118 267 1.44E-6 T 06-07-2017 IPR011256 Regulatory factor, effector binding domain CAK77_RS12575 e48c214f4f7bbb206bb8053758900df8 275 Pfam PF13411 MerR HTH family regulatory protein 6 73 1.2E-12 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAK77_RS12575 e48c214f4f7bbb206bb8053758900df8 275 SMART SM00871 116 268 3.5E-5 T 06-07-2017 IPR010499 Bacterial transcription activator, effector binding CAK77_RS12575 e48c214f4f7bbb206bb8053758900df8 275 SMART SM00422 5 75 4.8E-10 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAK77_RS12575 e48c214f4f7bbb206bb8053758900df8 275 SUPERFAMILY SSF46955 6 109 2.31E-22 T 06-07-2017 IPR009061 Putative DNA-binding domain CAK77_RS16110 bb6f419155b6f98d957ea47f58d1b3ec 793 SUPERFAMILY SSF81891 324 557 1.45E-14 T 06-07-2017 CAK77_RS16110 bb6f419155b6f98d957ea47f58d1b3ec 793 Pfam PF08335 GlnD PII-uridylyltransferase 168 202 1.5E-4 T 06-07-2017 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 CAK77_RS16110 bb6f419155b6f98d957ea47f58d1b3ec 793 SUPERFAMILY SSF55021 594 659 1.37E-5 T 06-07-2017 CAK77_RS16110 bb6f419155b6f98d957ea47f58d1b3ec 793 Gene3D G3DSA:1.10.3210.10 395 557 2.1E-13 T 06-07-2017 IPR006674 HD domain CAK77_RS16110 bb6f419155b6f98d957ea47f58d1b3ec 793 SMART SM00471 413 546 2.8E-7 T 06-07-2017 IPR003607 HD/PDEase domain CAK77_RS16110 bb6f419155b6f98d957ea47f58d1b3ec 793 SUPERFAMILY SSF81301 18 142 1.17E-15 T 06-07-2017 CAK77_RS16110 bb6f419155b6f98d957ea47f58d1b3ec 793 SUPERFAMILY SSF81593 176 271 7.85E-5 T 06-07-2017 CAK77_RS16110 bb6f419155b6f98d957ea47f58d1b3ec 793 TIGRFAM TIGR01693 UTase_glnD: protein-P-II uridylyltransferase 23 569 1.1E-174 T 06-07-2017 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 CAK77_RS16110 bb6f419155b6f98d957ea47f58d1b3ec 793 Gene3D G3DSA:3.30.70.260 595 644 3.4E-4 T 06-07-2017 CAK77_RS16110 bb6f419155b6f98d957ea47f58d1b3ec 793 Gene3D G3DSA:3.30.70.260 718 768 2.9E-6 T 06-07-2017 CAK77_RS16110 bb6f419155b6f98d957ea47f58d1b3ec 793 Hamap MF_00277 Bifunctional uridylyltransferase/uridylyl-removing enzyme [glnD]. 1 793 65.462 T 06-07-2017 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 CAK77_RS16110 bb6f419155b6f98d957ea47f58d1b3ec 793 Gene3D G3DSA:3.30.460.10 69 117 0.001 T 06-07-2017 CAK77_RS16110 bb6f419155b6f98d957ea47f58d1b3ec 793 Gene3D G3DSA:3.30.460.10 22 68 3.5E-5 T 06-07-2017 CAK77_RS16110 bb6f419155b6f98d957ea47f58d1b3ec 793 SUPERFAMILY SSF55021 718 777 2.56E-7 T 06-07-2017 CAK77_RS16110 bb6f419155b6f98d957ea47f58d1b3ec 793 Pfam PF01966 HD domain 419 535 6.4E-11 T 06-07-2017 IPR006674 HD domain CAK77_RS15940 abf4b5164f348573ae4e5b1f3a916e9a 304 Gene3D G3DSA:1.10.443.10 116 296 9.9E-52 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAK77_RS15940 abf4b5164f348573ae4e5b1f3a916e9a 304 SUPERFAMILY SSF56349 5 297 3.53E-52 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CAK77_RS15940 abf4b5164f348573ae4e5b1f3a916e9a 304 Gene3D G3DSA:1.10.150.130 7 102 1.7E-21 T 06-07-2017 IPR023109 Integrase/recombinase, N-terminal CAK77_RS15940 abf4b5164f348573ae4e5b1f3a916e9a 304 Pfam PF00589 Phage integrase family 115 289 1.1E-41 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAK77_RS15940 abf4b5164f348573ae4e5b1f3a916e9a 304 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 9 93 9.2E-18 T 06-07-2017 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CAK77_RS15940 abf4b5164f348573ae4e5b1f3a916e9a 304 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 7 304 53.992 T 06-07-2017 IPR023009 Tyrosine recombinase XerC/XerD CAK77_RS16185 eb6e1f950401e29e5338c98e61a31d3a 686 SUPERFAMILY SSF81653 114 206 3.01E-20 T 06-07-2017 CAK77_RS16185 eb6e1f950401e29e5338c98e61a31d3a 686 Pfam PF00702 haloacid dehalogenase-like hydrolase 300 533 1.1E-32 T 06-07-2017 CAK77_RS16185 eb6e1f950401e29e5338c98e61a31d3a 686 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 412 607 1.2E-40 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CAK77_RS16185 eb6e1f950401e29e5338c98e61a31d3a 686 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 70 331 2.3E-30 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CAK77_RS16185 eb6e1f950401e29e5338c98e61a31d3a 686 Pfam PF00122 E1-E2 ATPase 70 295 1.0E-43 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 CAK77_RS16185 eb6e1f950401e29e5338c98e61a31d3a 686 Gene3D G3DSA:3.40.50.1000 447 565 4.8E-36 T 06-07-2017 IPR023214 HAD-like domain CAK77_RS16185 eb6e1f950401e29e5338c98e61a31d3a 686 Gene3D G3DSA:2.70.150.10 49 207 1.0E-22 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 CAK77_RS16185 eb6e1f950401e29e5338c98e61a31d3a 686 TIGRFAM TIGR01497 kdpB: K+-transporting ATPase, B subunit 13 679 3.2E-293 T 06-07-2017 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 CAK77_RS16185 eb6e1f950401e29e5338c98e61a31d3a 686 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 306 312 - T 06-07-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CAK77_RS16185 eb6e1f950401e29e5338c98e61a31d3a 686 SUPERFAMILY SSF56784 438 562 9.28E-39 T 06-07-2017 IPR023214 HAD-like domain CAK77_RS16185 eb6e1f950401e29e5338c98e61a31d3a 686 SUPERFAMILY SSF56784 351 398 9.28E-39 T 06-07-2017 IPR023214 HAD-like domain CAK77_RS16185 eb6e1f950401e29e5338c98e61a31d3a 686 SUPERFAMILY SSF56784 292 316 9.28E-39 T 06-07-2017 IPR023214 HAD-like domain CAK77_RS16185 eb6e1f950401e29e5338c98e61a31d3a 686 Gene3D G3DSA:3.40.1110.10 315 446 3.3E-37 T 06-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CAK77_RS16185 eb6e1f950401e29e5338c98e61a31d3a 686 SUPERFAMILY SSF81665 207 298 7.59E-12 T 06-07-2017 CAK77_RS16185 eb6e1f950401e29e5338c98e61a31d3a 686 SUPERFAMILY SSF81665 37 101 7.59E-12 T 06-07-2017 CAK77_RS16185 eb6e1f950401e29e5338c98e61a31d3a 686 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 153 167 1.8E-26 T 06-07-2017 CAK77_RS16185 eb6e1f950401e29e5338c98e61a31d3a 686 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 542 554 1.8E-26 T 06-07-2017 CAK77_RS16185 eb6e1f950401e29e5338c98e61a31d3a 686 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 444 455 1.8E-26 T 06-07-2017 CAK77_RS16185 eb6e1f950401e29e5338c98e61a31d3a 686 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 519 538 1.8E-26 T 06-07-2017 CAK77_RS16185 eb6e1f950401e29e5338c98e61a31d3a 686 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 466 476 1.8E-26 T 06-07-2017 CAK77_RS16185 eb6e1f950401e29e5338c98e61a31d3a 686 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 304 318 1.8E-26 T 06-07-2017 CAK77_RS16185 eb6e1f950401e29e5338c98e61a31d3a 686 Hamap MF_00285 Potassium-transporting ATPase ATP-binding subunit [kdpB]. 13 683 39.561 T 06-07-2017 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 CAK77_RS20165 ec963ebd9fa2bd583a890aee29283133 284 Pfam PF10118 Predicted metal-dependent hydrolase 10 259 7.2E-68 T 06-07-2017 IPR016516 Uncharacterised conserved protein UCP07580 CAK77_RS20165 ec963ebd9fa2bd583a890aee29283133 284 PIRSF PIRSF007580 1 277 9.2E-61 T 06-07-2017 IPR016516 Uncharacterised conserved protein UCP07580 CAK77_RS14145 05462f10625a3272c6be28189b513485 283 Pfam PF13622 Thioesterase-like superfamily 30 265 1.9E-58 T 06-07-2017 CAK77_RS14145 05462f10625a3272c6be28189b513485 283 Gene3D G3DSA:3.10.129.10 2 110 1.4E-44 T 06-07-2017 IPR029069 HotDog domain CAK77_RS14145 05462f10625a3272c6be28189b513485 283 SUPERFAMILY SSF54637 2 108 9.24E-38 T 06-07-2017 IPR029069 HotDog domain CAK77_RS14145 05462f10625a3272c6be28189b513485 283 Gene3D G3DSA:3.10.129.10 120 268 4.1E-49 T 06-07-2017 IPR029069 HotDog domain CAK77_RS14145 05462f10625a3272c6be28189b513485 283 SUPERFAMILY SSF54637 112 267 4.42E-46 T 06-07-2017 IPR029069 HotDog domain CAK77_RS11930 e814a5aba092e0575533e4e2d9f2e31a 499 SUPERFAMILY SSF56176 47 242 3.36E-44 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAK77_RS11930 e814a5aba092e0575533e4e2d9f2e31a 499 Gene3D G3DSA:3.30.465.10 136 241 4.5E-9 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAK77_RS11930 e814a5aba092e0575533e4e2d9f2e31a 499 ProSitePatterns PS00862 Oxygen oxidoreductases covalent FAD-binding site. 81 114 - T 06-07-2017 IPR006093 Oxygen oxidoreductase covalent FAD-binding site GO:0016491|GO:0055114 CAK77_RS11930 e814a5aba092e0575533e4e2d9f2e31a 499 Pfam PF08031 Berberine and berberine like 454 498 9.7E-14 T 06-07-2017 IPR012951 Berberine/berberine-like GO:0016491|GO:0050660|GO:0055114 CAK77_RS11930 e814a5aba092e0575533e4e2d9f2e31a 499 Pfam PF01565 FAD binding domain 81 213 3.6E-28 T 06-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CAK77_RS11930 e814a5aba092e0575533e4e2d9f2e31a 499 Gene3D G3DSA:3.30.43.10 80 135 2.6E-10 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CAK77_RS10895 08d0aac3465e58a8f244d553496aee46 237 Pfam PF04954 Siderophore-interacting protein 130 236 2.9E-18 T 06-07-2017 IPR007037 Siderophore-interacting protein CAK77_RS10895 08d0aac3465e58a8f244d553496aee46 237 SUPERFAMILY SSF63380 23 121 2.98E-10 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CAK77_RS10895 08d0aac3465e58a8f244d553496aee46 237 Pfam PF08021 Siderophore-interacting FAD-binding domain 33 113 1.6E-11 T 06-07-2017 IPR013113 FAD-binding 9, siderophore-interacting CAK77_RS10895 08d0aac3465e58a8f244d553496aee46 237 Gene3D G3DSA:2.40.30.10 24 114 1.8E-19 T 06-07-2017 CAK77_RS10895 08d0aac3465e58a8f244d553496aee46 237 Gene3D G3DSA:3.40.50.80 124 236 9.1E-24 T 06-07-2017 CAK77_RS17425 25b5e8e3ea5243d72876da143b8c0c94 296 Pfam PF09339 IclR helix-turn-helix domain 7 58 2.0E-11 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAK77_RS17425 25b5e8e3ea5243d72876da143b8c0c94 296 Gene3D G3DSA:3.30.450.40 78 196 1.3E-22 T 06-07-2017 IPR029016 GAF domain-like CAK77_RS17425 25b5e8e3ea5243d72876da143b8c0c94 296 Gene3D G3DSA:3.30.450.40 241 286 1.3E-22 T 06-07-2017 IPR029016 GAF domain-like CAK77_RS17425 25b5e8e3ea5243d72876da143b8c0c94 296 SUPERFAMILY SSF46785 7 78 9.98E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS17425 25b5e8e3ea5243d72876da143b8c0c94 296 SUPERFAMILY SSF55781 231 286 6.38E-14 T 06-07-2017 IPR029016 GAF domain-like CAK77_RS17425 25b5e8e3ea5243d72876da143b8c0c94 296 SUPERFAMILY SSF55781 81 187 6.38E-14 T 06-07-2017 IPR029016 GAF domain-like CAK77_RS17425 25b5e8e3ea5243d72876da143b8c0c94 296 Gene3D G3DSA:1.10.10.10 4 77 1.8E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS17425 25b5e8e3ea5243d72876da143b8c0c94 296 SMART SM00346 5 96 1.7E-11 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAK77_RS17425 25b5e8e3ea5243d72876da143b8c0c94 296 Pfam PF01614 Bacterial transcriptional regulator 241 285 1.3E-4 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAK77_RS06545 323aa0f8a7a40c62de2b7eadb5b63e65 299 SUPERFAMILY SSF55021 22 99 4.96E-13 T 06-07-2017 CAK77_RS06545 323aa0f8a7a40c62de2b7eadb5b63e65 299 Gene3D G3DSA:3.40.50.170 104 294 2.6E-57 T 06-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CAK77_RS06545 323aa0f8a7a40c62de2b7eadb5b63e65 299 Gene3D G3DSA:3.30.70.260 20 100 2.7E-16 T 06-07-2017 CAK77_RS06545 323aa0f8a7a40c62de2b7eadb5b63e65 299 Pfam PF01842 ACT domain 23 66 6.7E-8 T 06-07-2017 IPR002912 ACT domain GO:0008152|GO:0016597 CAK77_RS06545 323aa0f8a7a40c62de2b7eadb5b63e65 299 Pfam PF00551 Formyl transferase 105 281 1.5E-37 T 06-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CAK77_RS06545 323aa0f8a7a40c62de2b7eadb5b63e65 299 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 251 273 1.5E-55 T 06-07-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CAK77_RS06545 323aa0f8a7a40c62de2b7eadb5b63e65 299 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 56 68 1.5E-55 T 06-07-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CAK77_RS06545 323aa0f8a7a40c62de2b7eadb5b63e65 299 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 106 128 1.5E-55 T 06-07-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CAK77_RS06545 323aa0f8a7a40c62de2b7eadb5b63e65 299 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 23 49 1.5E-55 T 06-07-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CAK77_RS06545 323aa0f8a7a40c62de2b7eadb5b63e65 299 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 128 155 1.5E-55 T 06-07-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CAK77_RS06545 323aa0f8a7a40c62de2b7eadb5b63e65 299 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 273 298 1.5E-55 T 06-07-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CAK77_RS06545 323aa0f8a7a40c62de2b7eadb5b63e65 299 PIRSF PIRSF036480 18 299 1.5E-106 T 06-07-2017 CAK77_RS06545 323aa0f8a7a40c62de2b7eadb5b63e65 299 SUPERFAMILY SSF53328 105 294 4.71E-57 T 06-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CAK77_RS06545 323aa0f8a7a40c62de2b7eadb5b63e65 299 TIGRFAM TIGR00655 PurU: formyltetrahydrofolate deformylase 22 299 7.9E-118 T 06-07-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CAK77_RS06545 323aa0f8a7a40c62de2b7eadb5b63e65 299 Hamap MF_01927 Formyltetrahydrofolate deformylase [purU]. 18 299 43.865 T 06-07-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CAK77_RS11460 06b138c0536e0f9d8d928dd752997dff 437 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 55 77 5.9E-30 T 06-07-2017 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CAK77_RS11460 06b138c0536e0f9d8d928dd752997dff 437 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 173 188 5.9E-30 T 06-07-2017 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CAK77_RS11460 06b138c0536e0f9d8d928dd752997dff 437 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 194 216 5.9E-30 T 06-07-2017 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CAK77_RS11460 06b138c0536e0f9d8d928dd752997dff 437 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 227 239 5.9E-30 T 06-07-2017 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CAK77_RS11460 06b138c0536e0f9d8d928dd752997dff 437 Gene3D G3DSA:1.10.240.10 245 328 6.0E-38 T 06-07-2017 CAK77_RS11460 06b138c0536e0f9d8d928dd752997dff 437 Pfam PF01479 S4 domain 372 406 1.3E-6 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 CAK77_RS11460 06b138c0536e0f9d8d928dd752997dff 437 Pfam PF00579 tRNA synthetases class I (W and Y) 41 335 9.1E-78 T 06-07-2017 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK77_RS11460 06b138c0536e0f9d8d928dd752997dff 437 Gene3D G3DSA:3.40.50.620 13 244 1.9E-89 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS11460 06b138c0536e0f9d8d928dd752997dff 437 Gene3D G3DSA:3.10.290.10 329 434 1.4E-26 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 CAK77_RS11460 06b138c0536e0f9d8d928dd752997dff 437 SUPERFAMILY SSF55174 363 433 7.85E-16 T 06-07-2017 CAK77_RS11460 06b138c0536e0f9d8d928dd752997dff 437 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 51 61 - T 06-07-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK77_RS11460 06b138c0536e0f9d8d928dd752997dff 437 Hamap MF_02006 Tyrosine--tRNA ligase [tyrS]. 13 435 42.622 T 06-07-2017 IPR024107 Tyrosine-tRNA ligase, bacterial-type, type 1 GO:0004831 KEGG: 00970+6.1.1.1 CAK77_RS11460 06b138c0536e0f9d8d928dd752997dff 437 SUPERFAMILY SSF52374 14 335 6.33E-93 T 06-07-2017 CAK77_RS11460 06b138c0536e0f9d8d928dd752997dff 437 SMART SM00363 370 431 6.6E-8 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 CAK77_RS11460 06b138c0536e0f9d8d928dd752997dff 437 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 13 433 8.5E-109 T 06-07-2017 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CAK77_RS10335 b48f25df54fb65350d17a8bb1ba2a35e 384 PIRSF PIRSF000138 8 383 8.0E-101 T 06-07-2017 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 CAK77_RS10335 b48f25df54fb65350d17a8bb1ba2a35e 384 Pfam PF01070 FMN-dependent dehydrogenase 33 380 4.8E-100 T 06-07-2017 IPR000262 FMN-dependent dehydrogenase GO:0016491 CAK77_RS10335 b48f25df54fb65350d17a8bb1ba2a35e 384 SUPERFAMILY SSF51395 24 378 2.25E-75 T 06-07-2017 CAK77_RS10335 b48f25df54fb65350d17a8bb1ba2a35e 384 Gene3D G3DSA:3.20.20.70 24 380 1.4E-108 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK77_RS10335 b48f25df54fb65350d17a8bb1ba2a35e 384 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 282 288 - T 06-07-2017 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 CAK77_RS05165 b5d498dcebb0099dd8f3714f51cd88cd 310 SUPERFAMILY SSF81982 30 150 5.62E-48 T 06-07-2017 IPR015250 MPT63-like GO:0005615 CAK77_RS05165 b5d498dcebb0099dd8f3714f51cd88cd 310 ProDom PD886639 ANTIGEN IMMUNOGENIC EXTRACELLULAR MPT63 MPB63 PRECURSOR IMMUNOPROTECTIVE SIGNAL SEQUENCING DIRECT 43 149 3.0E-23 T 06-07-2017 IPR015250 MPT63-like GO:0005615 CAK77_RS05165 b5d498dcebb0099dd8f3714f51cd88cd 310 Pfam PF09167 Domain of unknown function (DUF1942) 30 149 1.5E-51 T 06-07-2017 IPR015250 MPT63-like GO:0005615 CAK77_RS05165 b5d498dcebb0099dd8f3714f51cd88cd 310 Gene3D G3DSA:2.60.40.1240 30 150 1.6E-52 T 06-07-2017 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain CAK77_RS05730 f211ba6094d57411e94e2c1ad1f69792 448 SUPERFAMILY SSF51419 51 312 5.96E-69 T 06-07-2017 IPR029066 PLP-binding barrel CAK77_RS05730 f211ba6094d57411e94e2c1ad1f69792 448 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 62 310 1.4E-56 T 06-07-2017 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 CAK77_RS05730 f211ba6094d57411e94e2c1ad1f69792 448 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 29 444 1.2E-126 T 06-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAK77_RS05730 f211ba6094d57411e94e2c1ad1f69792 448 PRINTS PR01181 Diaminopimelate decarboxylase signature 412 434 1.4E-22 T 06-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAK77_RS05730 f211ba6094d57411e94e2c1ad1f69792 448 PRINTS PR01181 Diaminopimelate decarboxylase signature 97 114 1.4E-22 T 06-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAK77_RS05730 f211ba6094d57411e94e2c1ad1f69792 448 PRINTS PR01181 Diaminopimelate decarboxylase signature 183 192 1.4E-22 T 06-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAK77_RS05730 f211ba6094d57411e94e2c1ad1f69792 448 PRINTS PR01181 Diaminopimelate decarboxylase signature 329 347 1.4E-22 T 06-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAK77_RS05730 f211ba6094d57411e94e2c1ad1f69792 448 Gene3D G3DSA:3.20.20.10 59 297 1.0E-75 T 06-07-2017 IPR029066 PLP-binding barrel CAK77_RS05730 f211ba6094d57411e94e2c1ad1f69792 448 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 39 445 36.781 T 06-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAK77_RS05730 f211ba6094d57411e94e2c1ad1f69792 448 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 300 319 2.3E-17 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CAK77_RS05730 f211ba6094d57411e94e2c1ad1f69792 448 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 402 415 2.3E-17 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CAK77_RS05730 f211ba6094d57411e94e2c1ad1f69792 448 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 79 97 2.3E-17 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CAK77_RS05730 f211ba6094d57411e94e2c1ad1f69792 448 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 211 224 2.3E-17 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CAK77_RS05730 f211ba6094d57411e94e2c1ad1f69792 448 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 99 111 2.3E-17 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CAK77_RS05730 f211ba6094d57411e94e2c1ad1f69792 448 SUPERFAMILY SSF50621 286 444 1.76E-47 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CAK77_RS05730 f211ba6094d57411e94e2c1ad1f69792 448 Gene3D G3DSA:2.40.37.10 298 445 1.7E-46 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CAK77_RS05730 f211ba6094d57411e94e2c1ad1f69792 448 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 79 97 - T 06-07-2017 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site CAK77_RS05730 f211ba6094d57411e94e2c1ad1f69792 448 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 317 421 7.1E-17 T 06-07-2017 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 CAK77_RS12335 c33507b3481d1b4c59601cc8136abf9a 200 Gene3D G3DSA:1.10.357.10 4 183 2.4E-33 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS12335 c33507b3481d1b4c59601cc8136abf9a 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 8 54 1.9E-12 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS12335 c33507b3481d1b4c59601cc8136abf9a 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 8 21 1.3E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS12335 c33507b3481d1b4c59601cc8136abf9a 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 52 1.3E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS12335 c33507b3481d1b4c59601cc8136abf9a 200 Pfam PF13977 Bacterial transcriptional repressor 80 187 7.5E-14 T 06-07-2017 CAK77_RS12335 c33507b3481d1b4c59601cc8136abf9a 200 SUPERFAMILY SSF46689 4 73 1.99E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS12335 c33507b3481d1b4c59601cc8136abf9a 200 SUPERFAMILY SSF48498 78 185 1.78E-19 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS07045 87a37248f1e23696484c9114abf423a4 455 SUPERFAMILY SSF56176 4 214 1.26E-71 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAK77_RS07045 87a37248f1e23696484c9114abf423a4 455 Gene3D G3DSA:3.30.465.10 96 214 3.4E-38 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAK77_RS07045 87a37248f1e23696484c9114abf423a4 455 Pfam PF01565 FAD binding domain 41 178 5.3E-42 T 06-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CAK77_RS07045 87a37248f1e23696484c9114abf423a4 455 Pfam PF02913 FAD linked oxidases, C-terminal domain 221 453 9.3E-65 T 06-07-2017 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 CAK77_RS07045 87a37248f1e23696484c9114abf423a4 455 Gene3D G3DSA:1.10.45.10 415 452 2.2E-13 T 06-07-2017 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 CAK77_RS07045 87a37248f1e23696484c9114abf423a4 455 SUPERFAMILY SSF55103 191 454 1.21E-60 T 06-07-2017 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CAK77_RS07045 87a37248f1e23696484c9114abf423a4 455 Gene3D G3DSA:3.30.43.10 3 94 3.1E-28 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CAK77_RS13405 9c960198b4ffb86f3de2db3280f07741 542 ProSitePatterns PS00211 ABC transporters family signature. 453 467 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK77_RS13405 9c960198b4ffb86f3de2db3280f07741 542 ProSitePatterns PS00211 ABC transporters family signature. 162 176 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK77_RS13405 9c960198b4ffb86f3de2db3280f07741 542 SUPERFAMILY SSF52540 340 526 1.47E-45 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS13405 9c960198b4ffb86f3de2db3280f07741 542 SUPERFAMILY SSF52540 18 239 7.61E-35 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS13405 9c960198b4ffb86f3de2db3280f07741 542 SMART SM00382 28 242 1.6E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS13405 9c960198b4ffb86f3de2db3280f07741 542 SMART SM00382 360 527 6.4E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS13405 9c960198b4ffb86f3de2db3280f07741 542 Pfam PF00005 ABC transporter 353 481 9.4E-22 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK77_RS13405 9c960198b4ffb86f3de2db3280f07741 542 Pfam PF00005 ABC transporter 24 197 8.7E-18 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK77_RS13405 9c960198b4ffb86f3de2db3280f07741 542 Pfam PF12848 ABC transporter 242 314 1.8E-7 T 06-07-2017 IPR032781 ABC-transporter extension domain CAK77_RS13405 9c960198b4ffb86f3de2db3280f07741 542 Gene3D G3DSA:3.40.50.300 338 527 2.6E-41 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS13405 9c960198b4ffb86f3de2db3280f07741 542 Gene3D G3DSA:3.40.50.300 138 290 1.1E-38 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS13405 9c960198b4ffb86f3de2db3280f07741 542 Gene3D G3DSA:3.40.50.300 24 101 1.1E-38 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS13045 fe06bc0cceeccb057f92d197826e013d 142 SUPERFAMILY SSF54197 3 126 3.25E-36 T 06-07-2017 IPR011146 HIT-like domain GO:0003824 CAK77_RS13045 fe06bc0cceeccb057f92d197826e013d 142 Gene3D G3DSA:3.30.428.10 4 114 6.2E-33 T 06-07-2017 IPR011146 HIT-like domain GO:0003824 CAK77_RS13045 fe06bc0cceeccb057f92d197826e013d 142 PRINTS PR00332 Histidine triad family signature 6 22 4.0E-13 T 06-07-2017 IPR001310 Histidine triad (HIT) protein CAK77_RS13045 fe06bc0cceeccb057f92d197826e013d 142 PRINTS PR00332 Histidine triad family signature 94 104 4.0E-13 T 06-07-2017 IPR001310 Histidine triad (HIT) protein CAK77_RS13045 fe06bc0cceeccb057f92d197826e013d 142 PRINTS PR00332 Histidine triad family signature 27 45 4.0E-13 T 06-07-2017 IPR001310 Histidine triad (HIT) protein CAK77_RS13045 fe06bc0cceeccb057f92d197826e013d 142 Pfam PF01230 HIT domain 15 107 5.5E-22 T 06-07-2017 IPR001310 Histidine triad (HIT) protein CAK77_RS22390 09fc61ab99fe5e9513128c136644392a 607 ProSitePatterns PS00505 Phosphoenolpyruvate carboxykinase (GTP) signature. 269 277 - T 06-07-2017 IPR018091 Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site GO:0004613 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 CAK77_RS22390 09fc61ab99fe5e9513128c136644392a 607 Gene3D G3DSA:3.90.228.20 245 314 1.0E-31 T 06-07-2017 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CAK77_RS22390 09fc61ab99fe5e9513128c136644392a 607 Gene3D G3DSA:3.90.228.20 337 605 1.6E-99 T 06-07-2017 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CAK77_RS22390 09fc61ab99fe5e9513128c136644392a 607 SUPERFAMILY SSF68923 12 244 5.75E-96 T 06-07-2017 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CAK77_RS22390 09fc61ab99fe5e9513128c136644392a 607 Gene3D G3DSA:3.40.449.10 11 244 4.3E-94 T 06-07-2017 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CAK77_RS22390 09fc61ab99fe5e9513128c136644392a 607 Hamap MF_00452 Phosphoenolpyruvate carboxykinase [GTP] [pckG]. 10 606 51.469 T 06-07-2017 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 CAK77_RS22390 09fc61ab99fe5e9513128c136644392a 607 PIRSF PIRSF001348 1 607 1.9E-291 T 06-07-2017 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 CAK77_RS22390 09fc61ab99fe5e9513128c136644392a 607 Pfam PF00821 Phosphoenolpyruvate carboxykinase 22 605 1.6E-279 T 06-07-2017 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 CAK77_RS22390 09fc61ab99fe5e9513128c136644392a 607 SUPERFAMILY SSF53795 245 606 8.01E-154 T 06-07-2017 CAK77_RS08505 1808fbe0b82ec4324fb69a13c00bff7e 170 SUPERFAMILY SSF55486 5 147 7.08E-40 T 06-07-2017 CAK77_RS08505 1808fbe0b82ec4324fb69a13c00bff7e 170 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 2 158 21.0 T 06-07-2017 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 CAK77_RS08505 1808fbe0b82ec4324fb69a13c00bff7e 170 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 118 128 - T 06-07-2017 IPR020549 Endoribonuclease YbeY, conserved site CAK77_RS08505 1808fbe0b82ec4324fb69a13c00bff7e 170 Pfam PF02130 Uncharacterized protein family UPF0054 22 146 3.1E-37 T 06-07-2017 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 CAK77_RS08505 1808fbe0b82ec4324fb69a13c00bff7e 170 Gene3D G3DSA:3.40.390.30 7 149 1.9E-43 T 06-07-2017 IPR023091 Metalloprotease catalytic domain, predicted GO:0004222 CAK77_RS08505 1808fbe0b82ec4324fb69a13c00bff7e 170 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 36 148 4.0E-33 T 06-07-2017 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 CAK77_RS15145 7398bdf4f5cc1ce592c30288020f0ca2 464 Pfam PF01926 50S ribosome-binding GTPase 246 368 2.7E-20 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 CAK77_RS15145 7398bdf4f5cc1ce592c30288020f0ca2 464 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 46 408 3.8E-131 T 06-07-2017 IPR016496 GTPase HflX GO:0005525 CAK77_RS15145 7398bdf4f5cc1ce592c30288020f0ca2 464 Pfam PF16360 GTP-binding GTPase Middle Region 152 238 6.0E-30 T 06-07-2017 IPR032305 GTP-binding protein, middle domain CAK77_RS15145 7398bdf4f5cc1ce592c30288020f0ca2 464 Hamap MF_00900 GTPase HflX [hflX]. 65 438 47.726 T 06-07-2017 IPR016496 GTPase HflX GO:0005525 CAK77_RS15145 7398bdf4f5cc1ce592c30288020f0ca2 464 Gene3D G3DSA:3.40.50.300 244 410 4.1E-36 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS15145 7398bdf4f5cc1ce592c30288020f0ca2 464 PIRSF PIRSF006809 13 463 2.4E-162 T 06-07-2017 IPR016496 GTPase HflX GO:0005525 CAK77_RS15145 7398bdf4f5cc1ce592c30288020f0ca2 464 SUPERFAMILY SSF52540 245 438 4.35E-41 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS15145 7398bdf4f5cc1ce592c30288020f0ca2 464 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 313 331 2.7E-8 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 CAK77_RS15145 7398bdf4f5cc1ce592c30288020f0ca2 464 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 246 266 2.7E-8 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 CAK77_RS15145 7398bdf4f5cc1ce592c30288020f0ca2 464 Pfam PF13167 GTP-binding GTPase N-terminal 62 150 1.2E-32 T 06-07-2017 IPR025121 GTPase HflX, N-terminal CAK77_RS06920 94681f2ad875edbb83d78da7dda7f153 306 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 14 199 0.004 T 06-07-2017 CAK77_RS06920 94681f2ad875edbb83d78da7dda7f153 306 SUPERFAMILY SSF51735 14 280 8.41E-63 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS06920 94681f2ad875edbb83d78da7dda7f153 306 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 182 9.0E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06920 94681f2ad875edbb83d78da7dda7f153 306 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 89 100 9.0E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06920 94681f2ad875edbb83d78da7dda7f153 306 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 137 153 9.0E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06920 94681f2ad875edbb83d78da7dda7f153 306 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 184 201 9.0E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06920 94681f2ad875edbb83d78da7dda7f153 306 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 15 32 9.0E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06920 94681f2ad875edbb83d78da7dda7f153 306 Pfam PF00106 short chain dehydrogenase 14 205 3.3E-52 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06920 94681f2ad875edbb83d78da7dda7f153 306 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 150 178 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK77_RS06920 94681f2ad875edbb83d78da7dda7f153 306 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 163 182 2.6E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06920 94681f2ad875edbb83d78da7dda7f153 306 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 89 100 2.6E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06920 94681f2ad875edbb83d78da7dda7f153 306 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 143 151 2.6E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06920 94681f2ad875edbb83d78da7dda7f153 306 Gene3D G3DSA:3.40.50.720 14 252 5.2E-65 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS04695 029f01f3af5d9dfc4d50e29e1b47d9db 470 Gene3D G3DSA:1.10.287.130 247 307 1.3E-9 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK77_RS04695 029f01f3af5d9dfc4d50e29e1b47d9db 470 PRINTS PR00344 Bacterial sensor protein C-terminal signature 455 468 2.3E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK77_RS04695 029f01f3af5d9dfc4d50e29e1b47d9db 470 PRINTS PR00344 Bacterial sensor protein C-terminal signature 431 449 2.3E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK77_RS04695 029f01f3af5d9dfc4d50e29e1b47d9db 470 PRINTS PR00344 Bacterial sensor protein C-terminal signature 417 427 2.3E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK77_RS04695 029f01f3af5d9dfc4d50e29e1b47d9db 470 PRINTS PR00344 Bacterial sensor protein C-terminal signature 399 413 2.3E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK77_RS04695 029f01f3af5d9dfc4d50e29e1b47d9db 470 SMART SM00388 255 321 4.4E-11 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK77_RS04695 029f01f3af5d9dfc4d50e29e1b47d9db 470 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 365 468 3.0E-20 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS04695 029f01f3af5d9dfc4d50e29e1b47d9db 470 SUPERFAMILY SSF47384 240 316 1.45E-11 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK77_RS04695 029f01f3af5d9dfc4d50e29e1b47d9db 470 SUPERFAMILY SSF55874 328 468 1.7E-28 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS04695 029f01f3af5d9dfc4d50e29e1b47d9db 470 Pfam PF00512 His Kinase A (phospho-acceptor) domain 257 317 4.4E-10 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK77_RS04695 029f01f3af5d9dfc4d50e29e1b47d9db 470 Gene3D G3DSA:3.30.565.10 326 468 7.6E-31 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS04695 029f01f3af5d9dfc4d50e29e1b47d9db 470 SMART SM00387 363 470 2.6E-24 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS01025 d4e2ab655bab51fc79b6339b6afc7076 187 Pfam PF01569 PAP2 superfamily 77 176 7.9E-15 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CAK77_RS01025 d4e2ab655bab51fc79b6339b6afc7076 187 SUPERFAMILY SSF48317 10 175 4.58E-37 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CAK77_RS01025 d4e2ab655bab51fc79b6339b6afc7076 187 SMART SM00014 70 174 9.2E-12 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CAK77_RS01025 d4e2ab655bab51fc79b6339b6afc7076 187 Gene3D G3DSA:1.20.144.10 20 186 1.5E-26 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CAK77_RS03185 ae684fd4016aaf2e36ea3d398c480b9c 387 Gene3D G3DSA:1.10.540.10 4 119 4.6E-27 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS03185 ae684fd4016aaf2e36ea3d398c480b9c 387 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 118 1.4E-23 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS03185 ae684fd4016aaf2e36ea3d398c480b9c 387 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 211 8.3E-21 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAK77_RS03185 ae684fd4016aaf2e36ea3d398c480b9c 387 SUPERFAMILY SSF47203 228 383 2.09E-13 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS03185 ae684fd4016aaf2e36ea3d398c480b9c 387 Gene3D G3DSA:1.20.140.10 217 385 1.4E-26 T 06-07-2017 CAK77_RS03185 ae684fd4016aaf2e36ea3d398c480b9c 387 SUPERFAMILY SSF56645 4 241 2.23E-72 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK77_RS03185 ae684fd4016aaf2e36ea3d398c480b9c 387 Gene3D G3DSA:2.40.110.10 121 216 7.7E-36 T 06-07-2017 CAK77_RS03185 ae684fd4016aaf2e36ea3d398c480b9c 387 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 228 377 1.9E-20 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS04655 d35f15ca21377b4a16117edd269840ab 311 Gene3D G3DSA:3.20.20.30 2 306 6.9E-66 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS04655 d35f15ca21377b4a16117edd269840ab 311 Pfam PF00296 Luciferase-like monooxygenase 3 296 1.3E-52 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS04655 d35f15ca21377b4a16117edd269840ab 311 SUPERFAMILY SSF51679 1 306 7.8E-63 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS04655 d35f15ca21377b4a16117edd269840ab 311 TIGRFAM TIGR03557 F420_G6P_family: F420-dependent oxidoreductase, G6PDH family 4 309 7.5E-143 T 06-07-2017 IPR019945 F420-dependent glucose-6-phosphate dehydrogenase-related CAK77_RS15710 f4ebc6c9cb9568acd2dd3063605dd269 622 Pfam PF07728 AAA domain (dynein-related subfamily) 35 167 2.4E-12 T 06-07-2017 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 CAK77_RS15710 f4ebc6c9cb9568acd2dd3063605dd269 622 SUPERFAMILY SSF52540 8 296 4.47E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS15710 f4ebc6c9cb9568acd2dd3063605dd269 622 Pfam PF13519 von Willebrand factor type A domain 442 548 3.3E-14 T 06-07-2017 IPR002035 von Willebrand factor, type A CAK77_RS15710 f4ebc6c9cb9568acd2dd3063605dd269 622 Gene3D G3DSA:1.10.8.80 220 305 3.3E-34 T 06-07-2017 CAK77_RS15710 f4ebc6c9cb9568acd2dd3063605dd269 622 SMART SM00382 31 177 1.9E-5 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS15710 f4ebc6c9cb9568acd2dd3063605dd269 622 SMART SM00327 439 612 4.4E-19 T 06-07-2017 IPR002035 von Willebrand factor, type A CAK77_RS15710 f4ebc6c9cb9568acd2dd3063605dd269 622 Gene3D G3DSA:3.40.50.300 8 171 9.4E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS15710 f4ebc6c9cb9568acd2dd3063605dd269 622 Gene3D G3DSA:3.40.50.410 442 579 4.4E-12 T 06-07-2017 IPR002035 von Willebrand factor, type A CAK77_RS15710 f4ebc6c9cb9568acd2dd3063605dd269 622 SUPERFAMILY SSF53300 442 604 1.07E-20 T 06-07-2017 IPR002035 von Willebrand factor, type A CAK77_RS17560 7e6260b1b8c8f145a4ef77b88158c4dc 443 SUPERFAMILY SSF56112 95 158 7.69E-24 T 06-07-2017 IPR011009 Protein kinase-like domain CAK77_RS17560 7e6260b1b8c8f145a4ef77b88158c4dc 443 SUPERFAMILY SSF56112 190 328 7.69E-24 T 06-07-2017 IPR011009 Protein kinase-like domain CAK77_RS17560 7e6260b1b8c8f145a4ef77b88158c4dc 443 Gene3D G3DSA:3.90.1200.10 160 212 2.6E-6 T 06-07-2017 CAK77_RS17560 7e6260b1b8c8f145a4ef77b88158c4dc 443 Gene3D G3DSA:3.90.1200.10 276 303 2.6E-6 T 06-07-2017 CAK77_RS17560 7e6260b1b8c8f145a4ef77b88158c4dc 443 Pfam PF03109 ABC1 family 113 227 1.4E-33 T 06-07-2017 IPR004147 UbiB domain CAK77_RS12635 257cf36a66f196fa05e6e7342007991d 683 Pfam PF00665 Integrase core domain 256 411 7.6E-8 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 CAK77_RS12635 257cf36a66f196fa05e6e7342007991d 683 SUPERFAMILY SSF53098 361 482 2.73E-9 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAK77_RS12635 257cf36a66f196fa05e6e7342007991d 683 Pfam PF09299 Mu transposase, C-terminal 502 567 2.9E-7 T 06-07-2017 IPR015378 Transposase-like, Mu, C-terminal CAK77_RS12635 257cf36a66f196fa05e6e7342007991d 683 Gene3D G3DSA:3.30.420.10 354 477 1.6E-17 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAK77_RS12635 257cf36a66f196fa05e6e7342007991d 683 Gene3D G3DSA:3.30.420.10 257 315 1.6E-17 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAK77_RS11800 574ceb7f92b4494d1ec9911ceb8ab11c 198 TIGRFAM TIGR03086 TIGR03086: TIGR03086 family protein 8 189 2.5E-39 T 06-07-2017 IPR017520 Conserved hypothetical protein CHP03086 CAK77_RS11800 574ceb7f92b4494d1ec9911ceb8ab11c 198 SUPERFAMILY SSF109854 7 139 2.96E-18 T 06-07-2017 CAK77_RS11800 574ceb7f92b4494d1ec9911ceb8ab11c 198 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 7 133 6.1E-12 T 06-07-2017 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 CAK77_RS11800 574ceb7f92b4494d1ec9911ceb8ab11c 198 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 7 158 9.6E-18 T 06-07-2017 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type CAK77_RS20120 faa6e815e8f2ba292e5afca2fe3a6ded 181 SUPERFAMILY SSF55961 24 168 1.08E-15 T 06-07-2017 CAK77_RS20120 faa6e815e8f2ba292e5afca2fe3a6ded 181 Gene3D G3DSA:3.30.530.20 26 138 9.7E-11 T 06-07-2017 IPR023393 START-like domain CAK77_RS20120 faa6e815e8f2ba292e5afca2fe3a6ded 181 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 25 172 2.6E-14 T 06-07-2017 IPR019587 Polyketide cyclase/dehydrase CAK77_RS08360 cf395e5a4344a3343a5ea2c8f2976fe7 199 SUPERFAMILY SSF50118 92 196 1.96E-9 T 06-07-2017 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CAK77_RS08360 cf395e5a4344a3343a5ea2c8f2976fe7 199 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 94 195 2.8E-9 T 06-07-2017 IPR003477 mRNA interferase PemK-like protein GO:0003677 CAK77_RS09740 0b53253495a6a6c68946981e0081209e 359 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 46 58 4.2E-5 T 06-07-2017 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CAK77_RS09740 0b53253495a6a6c68946981e0081209e 359 Pfam PF00953 Glycosyl transferase family 4 86 276 1.4E-38 T 06-07-2017 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 CAK77_RS09740 0b53253495a6a6c68946981e0081209e 359 ProSitePatterns PS01348 MraY family signature 2. 179 190 - T 06-07-2017 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CAK77_RS09740 0b53253495a6a6c68946981e0081209e 359 ProSitePatterns PS01347 MraY family signature 1. 46 58 - T 06-07-2017 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CAK77_RS09740 0b53253495a6a6c68946981e0081209e 359 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 15 345 2.7E-84 T 06-07-2017 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CAK77_RS09740 0b53253495a6a6c68946981e0081209e 359 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 3 350 22.748 T 06-07-2017 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CAK77_RS23780 6f9b80356bd708c821282532054a1022 216 PRINTS PR00088 Haem oxygenase signature 160 181 8.0E-26 T 06-07-2017 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|Reactome: R-HSA-189483|Reactome: R-HSA-917937 CAK77_RS23780 6f9b80356bd708c821282532054a1022 216 PRINTS PR00088 Haem oxygenase signature 46 71 8.0E-26 T 06-07-2017 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|Reactome: R-HSA-189483|Reactome: R-HSA-917937 CAK77_RS23780 6f9b80356bd708c821282532054a1022 216 PRINTS PR00088 Haem oxygenase signature 11 36 8.0E-26 T 06-07-2017 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|Reactome: R-HSA-189483|Reactome: R-HSA-917937 CAK77_RS23780 6f9b80356bd708c821282532054a1022 216 PRINTS PR00088 Haem oxygenase signature 120 141 8.0E-26 T 06-07-2017 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|Reactome: R-HSA-189483|Reactome: R-HSA-917937 CAK77_RS23780 6f9b80356bd708c821282532054a1022 216 PRINTS PR00088 Haem oxygenase signature 192 210 8.0E-26 T 06-07-2017 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|Reactome: R-HSA-189483|Reactome: R-HSA-917937 CAK77_RS23780 6f9b80356bd708c821282532054a1022 216 SUPERFAMILY SSF48613 11 212 1.06E-48 T 06-07-2017 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CAK77_RS23780 6f9b80356bd708c821282532054a1022 216 Gene3D G3DSA:1.20.910.10 4 209 4.8E-57 T 06-07-2017 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CAK77_RS23780 6f9b80356bd708c821282532054a1022 216 PIRSF PIRSF000343 1 216 1.6E-50 T 06-07-2017 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|Reactome: R-HSA-189483|Reactome: R-HSA-917937 CAK77_RS23780 6f9b80356bd708c821282532054a1022 216 Pfam PF01126 Heme oxygenase 11 206 1.1E-43 T 06-07-2017 IPR016053 Haem oxygenase-like GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|Reactome: R-HSA-189483|Reactome: R-HSA-917937 CAK77_RS23780 6f9b80356bd708c821282532054a1022 216 ProSitePatterns PS00593 Heme oxygenase signature. 123 133 - T 06-07-2017 IPR018207 Haem oxygenase conserved site GO:0004392|GO:0055114 KEGG: 00860+1.14.14.18|Reactome: R-HSA-189483|Reactome: R-HSA-917937 CAK77_RS02570 29999ba5413c4cd2242439cd1aa67d01 401 TIGRFAM TIGR00678 holB: DNA polymerase III, delta' subunit 27 210 4.5E-57 T 06-07-2017 IPR004622 DNA polymerase III, delta prime subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAK77_RS02570 29999ba5413c4cd2242439cd1aa67d01 401 SUPERFAMILY SSF52540 14 214 5.25E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS02570 29999ba5413c4cd2242439cd1aa67d01 401 Gene3D G3DSA:3.40.50.300 7 174 4.8E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS02570 29999ba5413c4cd2242439cd1aa67d01 401 Pfam PF13177 DNA polymerase III, delta subunit 30 173 1.6E-33 T 06-07-2017 CAK77_RS06775 3ea806c84a4f7e1afe4984b0a26cca94 392 TIGRFAM TIGR02149 glgA_Coryne: glycogen synthase, Corynebacterium family 3 391 2.3E-179 T 06-07-2017 IPR011875 Glycogen synthase, corynebacterial KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 CAK77_RS06775 3ea806c84a4f7e1afe4984b0a26cca94 392 SUPERFAMILY SSF53756 1 391 1.01E-82 T 06-07-2017 CAK77_RS06775 3ea806c84a4f7e1afe4984b0a26cca94 392 Pfam PF13439 Glycosyltransferase Family 4 16 177 2.4E-31 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 CAK77_RS06775 3ea806c84a4f7e1afe4984b0a26cca94 392 Pfam PF00534 Glycosyl transferases group 1 201 368 1.2E-28 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 CAK77_RS06775 3ea806c84a4f7e1afe4984b0a26cca94 392 Gene3D G3DSA:3.40.50.2000 162 368 6.9E-49 T 06-07-2017 CAK77_RS14115 bb1f8a947451562b24af9feef1b5ff3c 185 SUPERFAMILY SSF48498 77 182 4.45E-26 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS14115 bb1f8a947451562b24af9feef1b5ff3c 185 Gene3D G3DSA:1.10.10.60 4 61 1.7E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS14115 bb1f8a947451562b24af9feef1b5ff3c 185 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 5.2E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS14115 bb1f8a947451562b24af9feef1b5ff3c 185 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 5.2E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS14115 bb1f8a947451562b24af9feef1b5ff3c 185 Gene3D G3DSA:1.10.357.10 62 183 1.5E-30 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS14115 bb1f8a947451562b24af9feef1b5ff3c 185 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 61 3.1E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS14115 bb1f8a947451562b24af9feef1b5ff3c 185 SUPERFAMILY SSF46689 3 63 4.77E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS11790 b56e03abf6c0ba6964a576142e33e07d 215 Pfam PF01774 UreD urease accessory protein 33 165 6.6E-11 T 06-07-2017 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 CAK77_RS01340 2f90ab5d32398ae6112aaa05aa12ce12 310 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 37 300 8.1E-50 T 06-07-2017 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 CAK77_RS01340 2f90ab5d32398ae6112aaa05aa12ce12 310 Gene3D G3DSA:3.40.190.10 36 141 1.3E-38 T 06-07-2017 CAK77_RS01340 2f90ab5d32398ae6112aaa05aa12ce12 310 Gene3D G3DSA:3.40.190.10 254 304 1.3E-38 T 06-07-2017 CAK77_RS01340 2f90ab5d32398ae6112aaa05aa12ce12 310 Gene3D G3DSA:3.40.190.120 142 243 9.8E-27 T 06-07-2017 CAK77_RS01340 2f90ab5d32398ae6112aaa05aa12ce12 310 SUPERFAMILY SSF53850 37 303 4.34E-47 T 06-07-2017 CAK77_RS14545 08d0bc8e923d78beb386d6a0843509bb 200 Pfam PF12079 Protein of unknown function (DUF3558) 12 196 3.1E-24 T 06-07-2017 IPR024520 Protein of unknown function DUF3558 CAK77_RS18015 0d536b918fdf76dab590514999b54504 324 Pfam PF00107 Zinc-binding dehydrogenase 151 257 1.0E-24 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAK77_RS18015 0d536b918fdf76dab590514999b54504 324 SMART SM00829 11 322 1.4E-14 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAK77_RS18015 0d536b918fdf76dab590514999b54504 324 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 86 1.7E-7 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAK77_RS18015 0d536b918fdf76dab590514999b54504 324 Gene3D G3DSA:3.90.180.10 4 146 5.4E-41 T 06-07-2017 IPR011032 GroES-like CAK77_RS18015 0d536b918fdf76dab590514999b54504 324 SUPERFAMILY SSF50129 3 149 4.87E-34 T 06-07-2017 IPR011032 GroES-like CAK77_RS18015 0d536b918fdf76dab590514999b54504 324 Gene3D G3DSA:3.40.50.720 147 256 1.7E-27 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS18015 0d536b918fdf76dab590514999b54504 324 SUPERFAMILY SSF51735 111 264 6.85E-42 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS07370 b3df223995ec888f597bfc7c45faf248 307 Pfam PF14561 Tetratricopeptide repeat 224 307 9.2E-18 T 06-07-2017 CAK77_RS07370 b3df223995ec888f597bfc7c45faf248 307 SUPERFAMILY SSF52833 43 148 2.38E-18 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK77_RS07370 b3df223995ec888f597bfc7c45faf248 307 Gene3D G3DSA:3.40.30.10 43 147 3.7E-15 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK77_RS07370 b3df223995ec888f597bfc7c45faf248 307 Pfam PF00085 Thioredoxin 44 144 1.2E-5 T 06-07-2017 IPR013766 Thioredoxin domain GO:0045454 CAK77_RS07370 b3df223995ec888f597bfc7c45faf248 307 Gene3D G3DSA:1.25.40.10 231 307 9.1E-12 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK77_RS09970 3f5d5bf2c34a8f37804fbaa76ce42f25 145 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 28 62 9.5E-10 T 06-07-2017 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal CAK77_RS09970 3f5d5bf2c34a8f37804fbaa76ce42f25 145 SUPERFAMILY SSF50249 16 135 4.45E-30 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS09970 3f5d5bf2c34a8f37804fbaa76ce42f25 145 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 64 129 3.3E-21 T 06-07-2017 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal CAK77_RS04640 26b56b598cda676a66aac76d1889651a 425 PIRSF PIRSF001369 40 425 1.1E-154 T 06-07-2017 IPR024176 Citrate synthase, bacterial-type CAK77_RS04640 26b56b598cda676a66aac76d1889651a 425 SUPERFAMILY SSF48256 6 424 7.07E-156 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 CAK77_RS04640 26b56b598cda676a66aac76d1889651a 425 Gene3D G3DSA:1.10.230.10 284 376 9.8E-37 T 06-07-2017 IPR016143 Citrate synthase-like, small alpha subdomain Reactome: R-HSA-163765|Reactome: R-HSA-75105 CAK77_RS04640 26b56b598cda676a66aac76d1889651a 425 PRINTS PR00143 Citrate synthase signature 243 271 3.7E-54 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 CAK77_RS04640 26b56b598cda676a66aac76d1889651a 425 PRINTS PR00143 Citrate synthase signature 362 378 3.7E-54 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 CAK77_RS04640 26b56b598cda676a66aac76d1889651a 425 PRINTS PR00143 Citrate synthase signature 167 180 3.7E-54 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 CAK77_RS04640 26b56b598cda676a66aac76d1889651a 425 PRINTS PR00143 Citrate synthase signature 382 396 3.7E-54 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 CAK77_RS04640 26b56b598cda676a66aac76d1889651a 425 PRINTS PR00143 Citrate synthase signature 221 236 3.7E-54 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 CAK77_RS04640 26b56b598cda676a66aac76d1889651a 425 PRINTS PR00143 Citrate synthase signature 299 319 3.7E-54 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 CAK77_RS04640 26b56b598cda676a66aac76d1889651a 425 Pfam PF00285 Citrate synthase, C-terminal domain 48 413 1.2E-134 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 CAK77_RS04640 26b56b598cda676a66aac76d1889651a 425 ProSitePatterns PS00480 Citrate synthase signature. 306 318 - T 06-07-2017 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 CAK77_RS04640 26b56b598cda676a66aac76d1889651a 425 TIGRFAM TIGR01798 cit_synth_I: citrate (Si)-synthase 16 424 5.7E-176 T 06-07-2017 IPR010953 Citrate synthase, type I GO:0004108|GO:0005737 CAK77_RS04640 26b56b598cda676a66aac76d1889651a 425 Gene3D G3DSA:1.10.580.10 54 283 3.5E-95 T 06-07-2017 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 CAK77_RS05280 ed50303543cf3a51acb3f699c0846959 176 Gene3D G3DSA:2.170.150.20 51 175 1.1E-55 T 06-07-2017 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 CAK77_RS05280 ed50303543cf3a51acb3f699c0846959 176 Pfam PF01641 SelR domain 57 175 4.5E-50 T 06-07-2017 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 CAK77_RS05280 ed50303543cf3a51acb3f699c0846959 176 SUPERFAMILY SSF51316 52 175 1.52E-55 T 06-07-2017 IPR011057 Mss4-like CAK77_RS05280 ed50303543cf3a51acb3f699c0846959 176 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 54 175 4.9E-50 T 06-07-2017 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 CAK77_RS13020 fcc9a59f3e054249c5e9cfff1fadd95a 205 Pfam PF09534 Tryptophan-associated transmembrane protein (Trp_oprn_chp) 20 199 1.7E-44 T 06-07-2017 IPR019051 Trp biosynthesis associated, transmembrane protein, Oprn/Chp CAK77_RS13020 fcc9a59f3e054249c5e9cfff1fadd95a 205 TIGRFAM TIGR02234 trp_oprn_chp: membrane protein, TIGR02234 family 11 199 3.4E-40 T 06-07-2017 IPR011746 Trp biosynthesis associated, conserved hypothetical membrane protein CAK77_RS04545 de193aa5f6e2d5813d3c9cf8c21c740f 148 SMART SM00347 27 125 8.8E-21 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK77_RS04545 de193aa5f6e2d5813d3c9cf8c21c740f 148 Pfam PF01047 MarR family 34 92 3.5E-15 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK77_RS04545 de193aa5f6e2d5813d3c9cf8c21c740f 148 SUPERFAMILY SSF46785 5 136 2.73E-33 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS04545 de193aa5f6e2d5813d3c9cf8c21c740f 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 51 67 6.0E-5 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK77_RS04545 de193aa5f6e2d5813d3c9cf8c21c740f 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 87 103 6.0E-5 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK77_RS04545 de193aa5f6e2d5813d3c9cf8c21c740f 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 68 83 6.0E-5 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK77_RS04545 de193aa5f6e2d5813d3c9cf8c21c740f 148 Gene3D G3DSA:1.10.10.10 4 140 8.8E-39 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS22025 02f6803598fd06be02ba21fc4eea9de1 164 Pfam PF12903 Protein of unknown function (DUF3830) 7 163 6.0E-61 T 06-07-2017 IPR024532 Protein of unknown function DUF3830 CAK77_RS22025 02f6803598fd06be02ba21fc4eea9de1 164 SUPERFAMILY SSF50891 6 151 7.59E-9 T 06-07-2017 IPR029000 Cyclophilin-like domain CAK77_RS21510 d9769c310ab947231b84afc333aa9536 159 Pfam PF00578 AhpC/TSA family 32 137 2.8E-16 T 06-07-2017 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CAK77_RS21510 d9769c310ab947231b84afc333aa9536 159 ProSitePatterns PS00194 Thioredoxin family active site. 55 73 - T 06-07-2017 IPR017937 Thioredoxin, conserved site GO:0045454 CAK77_RS21510 d9769c310ab947231b84afc333aa9536 159 SUPERFAMILY SSF52833 2 153 3.38E-30 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK77_RS21510 d9769c310ab947231b84afc333aa9536 159 Gene3D G3DSA:3.40.30.10 2 158 2.6E-34 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK77_RS13275 0e83d3453b86e6d7d62e2b6fa3c8b0cd 323 SMART SM00382 50 200 0.0084 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS13275 0e83d3453b86e6d7d62e2b6fa3c8b0cd 323 Pfam PF03308 ArgK protein 19 291 5.7E-117 T 06-07-2017 CAK77_RS13275 0e83d3453b86e6d7d62e2b6fa3c8b0cd 323 TIGRFAM TIGR00750 lao: LAO/AO transport system ATPase 14 319 5.4E-124 T 06-07-2017 IPR005129 SIMIBI class G3E GTPase, ArgK/MeaB GO:0003924|GO:0005525 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CAK77_RS13275 0e83d3453b86e6d7d62e2b6fa3c8b0cd 323 SUPERFAMILY SSF52540 6 320 1.47E-93 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS13275 0e83d3453b86e6d7d62e2b6fa3c8b0cd 323 Gene3D G3DSA:1.20.5.170 4 51 1.5E-18 T 06-07-2017 CAK77_RS13275 0e83d3453b86e6d7d62e2b6fa3c8b0cd 323 Gene3D G3DSA:3.40.50.300 52 255 2.3E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS13275 0e83d3453b86e6d7d62e2b6fa3c8b0cd 323 Gene3D G3DSA:1.10.287.130 261 312 6.1E-4 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK77_RS21565 dbdf2acec972a270d4db922a1b00436d 293 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 9 214 1.0E-17 T 06-07-2017 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 CAK77_RS00580 f5779006b07c69e7fee29dbf7cfb936d 186 Gene3D G3DSA:1.10.357.10 3 182 1.1E-24 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS00580 f5779006b07c69e7fee29dbf7cfb936d 186 SUPERFAMILY SSF46689 13 80 1.18E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS00580 f5779006b07c69e7fee29dbf7cfb936d 186 ProSitePatterns PS01081 TetR-type HTH domain signature. 33 64 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CAK77_RS00580 f5779006b07c69e7fee29dbf7cfb936d 186 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 66 9.8E-17 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS00580 f5779006b07c69e7fee29dbf7cfb936d 186 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 1.2E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS00580 f5779006b07c69e7fee29dbf7cfb936d 186 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 1.2E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS05565 b5ab6c9534d523f7e4e9cdd06ff7e8e6 278 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 3 224 33.034 T 06-07-2017 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CAK77_RS05565 b5ab6c9534d523f7e4e9cdd06ff7e8e6 278 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 4 271 1.3E-63 T 06-07-2017 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CAK77_RS05565 b5ab6c9534d523f7e4e9cdd06ff7e8e6 278 Gene3D G3DSA:3.30.950.10 113 224 1.0E-45 T 06-07-2017 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAK77_RS05565 b5ab6c9534d523f7e4e9cdd06ff7e8e6 278 SUPERFAMILY SSF53790 1 222 7.2E-74 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAK77_RS05565 b5ab6c9534d523f7e4e9cdd06ff7e8e6 278 Gene3D G3DSA:3.40.1010.10 3 112 1.8E-8 T 06-07-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAK77_RS05565 b5ab6c9534d523f7e4e9cdd06ff7e8e6 278 PIRSF PIRSF005917 1 278 2.2E-87 T 06-07-2017 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CAK77_RS05565 b5ab6c9534d523f7e4e9cdd06ff7e8e6 278 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 4 206 4.1E-29 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAK77_RS16615 4cfae3c930cde7f1155ec78d3bbc549a 492 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 12 486 89.623 T 06-07-2017 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAK77_RS16615 4cfae3c930cde7f1155ec78d3bbc549a 492 SUPERFAMILY SSF75304 2 485 1.06E-155 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAK77_RS16615 4cfae3c930cde7f1155ec78d3bbc549a 492 Pfam PF01425 Amidase 25 474 1.6E-157 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAK77_RS16615 4cfae3c930cde7f1155ec78d3bbc549a 492 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 14 483 9.6E-190 T 06-07-2017 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAK77_RS16615 4cfae3c930cde7f1155ec78d3bbc549a 492 ProSitePatterns PS00571 Amidases signature. 153 184 - T 06-07-2017 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 CAK77_RS16615 4cfae3c930cde7f1155ec78d3bbc549a 492 Gene3D G3DSA:3.90.1300.10 3 486 1.0E-169 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAK77_RS05375 32080f8927bef4ac895004aff311e944 389 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 241 380 4.5E-28 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS05375 32080f8927bef4ac895004aff311e944 389 Gene3D G3DSA:2.40.110.10 125 222 9.1E-30 T 06-07-2017 CAK77_RS05375 32080f8927bef4ac895004aff311e944 389 SUPERFAMILY SSF47203 231 387 6.93E-37 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS05375 32080f8927bef4ac895004aff311e944 389 Gene3D G3DSA:1.10.540.10 10 120 1.0E-27 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS05375 32080f8927bef4ac895004aff311e944 389 SUPERFAMILY SSF56645 8 245 1.57E-62 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK77_RS05375 32080f8927bef4ac895004aff311e944 389 Gene3D G3DSA:1.20.140.10 223 388 7.7E-45 T 06-07-2017 CAK77_RS05375 32080f8927bef4ac895004aff311e944 389 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 10 120 6.1E-26 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS05375 32080f8927bef4ac895004aff311e944 389 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 125 209 9.5E-20 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAK77_RS01575 6b9d1521dcaf9fa0826524c34368fb71 677 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 250 378 1.4E-16 T 06-07-2017 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 CAK77_RS01575 6b9d1521dcaf9fa0826524c34368fb71 677 PRINTS PR01217 Proline rich extensin signature 442 463 2.8E-11 T 06-07-2017 CAK77_RS01575 6b9d1521dcaf9fa0826524c34368fb71 677 PRINTS PR01217 Proline rich extensin signature 476 492 2.8E-11 T 06-07-2017 CAK77_RS01575 6b9d1521dcaf9fa0826524c34368fb71 677 PRINTS PR01217 Proline rich extensin signature 428 440 2.8E-11 T 06-07-2017 CAK77_RS01575 6b9d1521dcaf9fa0826524c34368fb71 677 Pfam PF13177 DNA polymerase III, delta subunit 34 191 9.6E-39 T 06-07-2017 CAK77_RS01575 6b9d1521dcaf9fa0826524c34368fb71 677 SMART SM00382 50 193 1.2E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS01575 6b9d1521dcaf9fa0826524c34368fb71 677 Gene3D G3DSA:3.40.50.300 28 180 2.9E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS01575 6b9d1521dcaf9fa0826524c34368fb71 677 Gene3D G3DSA:1.20.272.10 259 378 9.2E-19 T 06-07-2017 CAK77_RS01575 6b9d1521dcaf9fa0826524c34368fb71 677 SUPERFAMILY SSF52540 47 236 4.79E-51 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS01575 6b9d1521dcaf9fa0826524c34368fb71 677 SUPERFAMILY SSF48019 260 377 1.53E-25 T 06-07-2017 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 CAK77_RS01575 6b9d1521dcaf9fa0826524c34368fb71 677 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 18 376 6.6E-113 T 06-07-2017 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 CAK77_RS01575 6b9d1521dcaf9fa0826524c34368fb71 677 Gene3D G3DSA:1.10.8.60 181 258 9.9E-20 T 06-07-2017 CAK77_RS00035 b811749aa1672c2a930ea5e75b8d2beb 675 SMART SM00433 41 668 0.0 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAK77_RS00035 b811749aa1672c2a930ea5e75b8d2beb 675 Gene3D G3DSA:3.40.50.670 439 657 2.0E-87 T 06-07-2017 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAK77_RS00035 b811749aa1672c2a930ea5e75b8d2beb 675 PRINTS PR00418 DNA topoisomerase II family signature 455 469 5.1E-69 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAK77_RS00035 b811749aa1672c2a930ea5e75b8d2beb 675 PRINTS PR00418 DNA topoisomerase II family signature 118 132 5.1E-69 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAK77_RS00035 b811749aa1672c2a930ea5e75b8d2beb 675 PRINTS PR00418 DNA topoisomerase II family signature 303 316 5.1E-69 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAK77_RS00035 b811749aa1672c2a930ea5e75b8d2beb 675 PRINTS PR00418 DNA topoisomerase II family signature 539 556 5.1E-69 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAK77_RS00035 b811749aa1672c2a930ea5e75b8d2beb 675 PRINTS PR00418 DNA topoisomerase II family signature 607 623 5.1E-69 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAK77_RS00035 b811749aa1672c2a930ea5e75b8d2beb 675 PRINTS PR00418 DNA topoisomerase II family signature 76 89 5.1E-69 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAK77_RS00035 b811749aa1672c2a930ea5e75b8d2beb 675 PRINTS PR00418 DNA topoisomerase II family signature 559 571 5.1E-69 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAK77_RS00035 b811749aa1672c2a930ea5e75b8d2beb 675 PRINTS PR00418 DNA topoisomerase II family signature 41 56 5.1E-69 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAK77_RS00035 b811749aa1672c2a930ea5e75b8d2beb 675 PRINTS PR00418 DNA topoisomerase II family signature 521 537 5.1E-69 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAK77_RS00035 b811749aa1672c2a930ea5e75b8d2beb 675 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 9 675 95.582 T 06-07-2017 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CAK77_RS00035 b811749aa1672c2a930ea5e75b8d2beb 675 SUPERFAMILY SSF54211 256 426 2.09E-60 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAK77_RS00035 b811749aa1672c2a930ea5e75b8d2beb 675 Pfam PF00204 DNA gyrase B 256 425 7.9E-64 T 06-07-2017 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAK77_RS00035 b811749aa1672c2a930ea5e75b8d2beb 675 SMART SM00387 37 179 4.9E-25 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS00035 b811749aa1672c2a930ea5e75b8d2beb 675 Pfam PF01751 Toprim domain 454 563 3.7E-16 T 06-07-2017 IPR006171 Toprim domain CAK77_RS00035 b811749aa1672c2a930ea5e75b8d2beb 675 Gene3D G3DSA:3.30.230.10 255 426 9.3E-76 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CAK77_RS00035 b811749aa1672c2a930ea5e75b8d2beb 675 SUPERFAMILY SSF55874 11 215 9.99E-68 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS00035 b811749aa1672c2a930ea5e75b8d2beb 675 ProSitePatterns PS00177 DNA topoisomerase II signature. 457 465 - T 06-07-2017 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAK77_RS00035 b811749aa1672c2a930ea5e75b8d2beb 675 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 606 663 4.2E-26 T 06-07-2017 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 CAK77_RS00035 b811749aa1672c2a930ea5e75b8d2beb 675 Gene3D G3DSA:3.30.565.10 12 217 2.9E-86 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS00035 b811749aa1672c2a930ea5e75b8d2beb 675 SUPERFAMILY SSF56719 429 670 4.45E-81 T 06-07-2017 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CAK77_RS00035 b811749aa1672c2a930ea5e75b8d2beb 675 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 12 675 1.6E-297 T 06-07-2017 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CAK77_RS00035 b811749aa1672c2a930ea5e75b8d2beb 675 PRINTS PR01159 DNA gyrase subunit B signature 184 199 5.3E-71 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CAK77_RS00035 b811749aa1672c2a930ea5e75b8d2beb 675 PRINTS PR01159 DNA gyrase subunit B signature 347 363 5.3E-71 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CAK77_RS00035 b811749aa1672c2a930ea5e75b8d2beb 675 PRINTS PR01159 DNA gyrase subunit B signature 395 409 5.3E-71 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CAK77_RS00035 b811749aa1672c2a930ea5e75b8d2beb 675 PRINTS PR01159 DNA gyrase subunit B signature 628 640 5.3E-71 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CAK77_RS00035 b811749aa1672c2a930ea5e75b8d2beb 675 PRINTS PR01159 DNA gyrase subunit B signature 12 22 5.3E-71 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CAK77_RS00035 b811749aa1672c2a930ea5e75b8d2beb 675 PRINTS PR01159 DNA gyrase subunit B signature 255 277 5.3E-71 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CAK77_RS00035 b811749aa1672c2a930ea5e75b8d2beb 675 PRINTS PR01159 DNA gyrase subunit B signature 409 429 5.3E-71 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CAK77_RS00035 b811749aa1672c2a930ea5e75b8d2beb 675 PRINTS PR01159 DNA gyrase subunit B signature 199 212 5.3E-71 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CAK77_RS00035 b811749aa1672c2a930ea5e75b8d2beb 675 PRINTS PR01159 DNA gyrase subunit B signature 505 514 5.3E-71 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CAK77_RS00035 b811749aa1672c2a930ea5e75b8d2beb 675 PRINTS PR01159 DNA gyrase subunit B signature 644 660 5.3E-71 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CAK77_RS00035 b811749aa1672c2a930ea5e75b8d2beb 675 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 39 178 4.3E-24 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS18105 c73f515a5c786f558e4acd915f995301 336 SUPERFAMILY SSF56112 8 322 7.4E-32 T 06-07-2017 IPR011009 Protein kinase-like domain CAK77_RS18105 c73f515a5c786f558e4acd915f995301 336 Pfam PF01636 Phosphotransferase enzyme family 28 255 1.8E-26 T 06-07-2017 IPR002575 Aminoglycoside phosphotransferase CAK77_RS18105 c73f515a5c786f558e4acd915f995301 336 Gene3D G3DSA:3.90.1200.10 125 286 4.3E-21 T 06-07-2017 CAK77_RS07375 2170453cb51e187b6b6992b0577b16da 484 Pfam PF04228 Putative neutral zinc metallopeptidase 57 266 2.1E-13 T 06-07-2017 IPR007343 Uncharacterised protein family, zinc metallopeptidase putative CAK77_RS07375 2170453cb51e187b6b6992b0577b16da 484 SUPERFAMILY SSF55486 60 216 2.75E-6 T 06-07-2017 CAK77_RS09050 21d1143619df4a1bef85a348fdbb0eb1 213 Gene3D G3DSA:1.10.357.10 76 207 2.1E-19 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS09050 21d1143619df4a1bef85a348fdbb0eb1 213 Gene3D G3DSA:1.10.10.60 22 75 1.7E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS09050 21d1143619df4a1bef85a348fdbb0eb1 213 SUPERFAMILY SSF48498 96 208 7.53E-20 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS09050 21d1143619df4a1bef85a348fdbb0eb1 213 Pfam PF00440 Bacterial regulatory proteins, tetR family 30 76 8.7E-12 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS09050 21d1143619df4a1bef85a348fdbb0eb1 213 SUPERFAMILY SSF46689 19 87 2.82E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS09050 21d1143619df4a1bef85a348fdbb0eb1 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 51 74 9.8E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS09050 21d1143619df4a1bef85a348fdbb0eb1 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 43 9.8E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS17010 8da750623bbaece46fea6abd1fbca6bc 712 SUPERFAMILY SSF51998 173 696 1.31E-185 T 06-07-2017 CAK77_RS17010 8da750623bbaece46fea6abd1fbca6bc 712 Pfam PF08343 Ribonucleotide reductase N-terminal 14 95 6.6E-31 T 06-07-2017 IPR013554 Ribonucleotide reductase N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CAK77_RS17010 8da750623bbaece46fea6abd1fbca6bc 712 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 564 586 - T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CAK77_RS17010 8da750623bbaece46fea6abd1fbca6bc 712 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 97 169 7.0E-12 T 06-07-2017 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CAK77_RS17010 8da750623bbaece46fea6abd1fbca6bc 712 PRINTS PR01183 Ribonucleotide reductase large chain signature 463 485 4.8E-33 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CAK77_RS17010 8da750623bbaece46fea6abd1fbca6bc 712 PRINTS PR01183 Ribonucleotide reductase large chain signature 380 391 4.8E-33 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CAK77_RS17010 8da750623bbaece46fea6abd1fbca6bc 712 PRINTS PR01183 Ribonucleotide reductase large chain signature 491 514 4.8E-33 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CAK77_RS17010 8da750623bbaece46fea6abd1fbca6bc 712 PRINTS PR01183 Ribonucleotide reductase large chain signature 575 602 4.8E-33 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CAK77_RS17010 8da750623bbaece46fea6abd1fbca6bc 712 PRINTS PR01183 Ribonucleotide reductase large chain signature 249 268 4.8E-33 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CAK77_RS17010 8da750623bbaece46fea6abd1fbca6bc 712 PRINTS PR01183 Ribonucleotide reductase large chain signature 424 447 4.8E-33 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CAK77_RS17010 8da750623bbaece46fea6abd1fbca6bc 712 Gene3D G3DSA:3.20.70.20 348 511 2.9E-52 T 06-07-2017 CAK77_RS17010 8da750623bbaece46fea6abd1fbca6bc 712 Gene3D G3DSA:3.20.70.20 575 689 2.9E-52 T 06-07-2017 CAK77_RS17010 8da750623bbaece46fea6abd1fbca6bc 712 Gene3D G3DSA:3.20.70.20 103 295 2.9E-52 T 06-07-2017 CAK77_RS17010 8da750623bbaece46fea6abd1fbca6bc 712 SUPERFAMILY SSF48168 13 172 3.4E-61 T 06-07-2017 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CAK77_RS17010 8da750623bbaece46fea6abd1fbca6bc 712 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 101 694 5.5E-157 T 06-07-2017 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CAK77_RS17010 8da750623bbaece46fea6abd1fbca6bc 712 TIGRFAM TIGR04170 RNR_1b_NrdE: ribonucleoside-diphosphate reductase, class 1b, alpha subunit 13 712 0.0 T 06-07-2017 IPR026459 Ribonucleotide reductase, class 1b, subunit NrdE KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CAK77_RS17010 8da750623bbaece46fea6abd1fbca6bc 712 Pfam PF02867 Ribonucleotide reductase, barrel domain 174 691 1.0E-142 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CAK77_RS11065 32b7c5b37b170449b941c0f2aeb1e487 250 Pfam PF00486 Transcriptional regulatory protein, C terminal 31 95 1.4E-9 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAK77_RS11065 32b7c5b37b170449b941c0f2aeb1e487 250 SUPERFAMILY SSF46894 5 95 9.64E-11 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAK77_RS11065 32b7c5b37b170449b941c0f2aeb1e487 250 Gene3D G3DSA:1.25.40.10 163 226 3.6E-6 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK77_RS11065 32b7c5b37b170449b941c0f2aeb1e487 250 Pfam PF03704 Bacterial transcriptional activator domain 102 240 1.1E-19 T 06-07-2017 IPR005158 Bacterial transcriptional activator domain CAK77_RS11065 32b7c5b37b170449b941c0f2aeb1e487 250 SUPERFAMILY SSF48452 102 243 1.56E-20 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK77_RS11065 32b7c5b37b170449b941c0f2aeb1e487 250 Gene3D G3DSA:1.10.10.10 31 96 3.7E-9 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS11065 32b7c5b37b170449b941c0f2aeb1e487 250 SMART SM01043 102 246 1.6E-14 T 06-07-2017 IPR005158 Bacterial transcriptional activator domain CAK77_RS04700 9461ef484bcfbe5d9cc4c53d4bef09a1 233 Pfam PF00072 Response regulator receiver domain 10 120 3.8E-29 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK77_RS04700 9461ef484bcfbe5d9cc4c53d4bef09a1 233 SMART SM00862 155 230 1.7E-27 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAK77_RS04700 9461ef484bcfbe5d9cc4c53d4bef09a1 233 SMART SM00448 8 119 2.1E-42 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK77_RS04700 9461ef484bcfbe5d9cc4c53d4bef09a1 233 Gene3D G3DSA:1.10.10.10 132 231 3.5E-33 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS04700 9461ef484bcfbe5d9cc4c53d4bef09a1 233 Pfam PF00486 Transcriptional regulatory protein, C terminal 157 230 6.3E-26 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAK77_RS04700 9461ef484bcfbe5d9cc4c53d4bef09a1 233 Gene3D G3DSA:3.40.50.2300 7 129 2.3E-41 T 06-07-2017 CAK77_RS04700 9461ef484bcfbe5d9cc4c53d4bef09a1 233 SUPERFAMILY SSF52172 7 181 3.56E-42 T 06-07-2017 IPR011006 CheY-like superfamily CAK77_RS01220 aa947f5ff2d93ce55508e6631e0efa09 303 Pfam PF04072 Leucine carboxyl methyltransferase 18 198 1.0E-52 T 06-07-2017 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 CAK77_RS01220 aa947f5ff2d93ce55508e6631e0efa09 303 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 16 274 2.7E-74 T 06-07-2017 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 CAK77_RS01220 aa947f5ff2d93ce55508e6631e0efa09 303 SUPERFAMILY SSF53335 14 295 6.81E-65 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS01220 aa947f5ff2d93ce55508e6631e0efa09 303 Gene3D G3DSA:3.40.50.150 78 213 3.6E-12 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS01730 414e55edb1a5d4fde696fd0e04f6a2be 421 SUPERFAMILY SSF55021 251 329 1.37E-18 T 06-07-2017 CAK77_RS01730 414e55edb1a5d4fde696fd0e04f6a2be 421 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 06-07-2017 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CAK77_RS01730 414e55edb1a5d4fde696fd0e04f6a2be 421 PIRSF PIRSF000726 54 414 8.6E-132 T 06-07-2017 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CAK77_RS01730 414e55edb1a5d4fde696fd0e04f6a2be 421 SUPERFAMILY SSF55021 332 409 5.49E-23 T 06-07-2017 CAK77_RS01730 414e55edb1a5d4fde696fd0e04f6a2be 421 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 63 405 2.0E-120 T 06-07-2017 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CAK77_RS01730 414e55edb1a5d4fde696fd0e04f6a2be 421 Pfam PF01842 ACT domain 269 329 1.5E-10 T 06-07-2017 IPR002912 ACT domain GO:0008152|GO:0016597 CAK77_RS01730 414e55edb1a5d4fde696fd0e04f6a2be 421 Gene3D G3DSA:3.40.1160.10 3 245 3.9E-74 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase CAK77_RS01730 414e55edb1a5d4fde696fd0e04f6a2be 421 Pfam PF00696 Amino acid kinase family 3 231 2.7E-54 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase CAK77_RS01730 414e55edb1a5d4fde696fd0e04f6a2be 421 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 2 406 4.1E-124 T 06-07-2017 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CAK77_RS01730 414e55edb1a5d4fde696fd0e04f6a2be 421 Pfam PF13840 ACT domain 341 403 1.5E-16 T 06-07-2017 IPR027795 GATS-like ACT domain CAK77_RS01730 414e55edb1a5d4fde696fd0e04f6a2be 421 Gene3D G3DSA:3.30.70.260 267 336 4.0E-4 T 06-07-2017 CAK77_RS01730 414e55edb1a5d4fde696fd0e04f6a2be 421 SUPERFAMILY SSF53633 4 243 3.14E-73 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase CAK77_RS14255 742179c90b8e4b8947d20f5c58d8d67e 206 SMART SM00421 142 199 6.8E-22 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK77_RS14255 742179c90b8e4b8947d20f5c58d8d67e 206 SUPERFAMILY SSF46894 137 205 2.01E-19 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAK77_RS14255 742179c90b8e4b8947d20f5c58d8d67e 206 Gene3D G3DSA:1.10.10.10 121 205 9.8E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS14255 742179c90b8e4b8947d20f5c58d8d67e 206 SMART SM00448 2 115 5.8E-32 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK77_RS14255 742179c90b8e4b8947d20f5c58d8d67e 206 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 145 159 1.2E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK77_RS14255 742179c90b8e4b8947d20f5c58d8d67e 206 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 159 175 1.2E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK77_RS14255 742179c90b8e4b8947d20f5c58d8d67e 206 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 175 187 1.2E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK77_RS14255 742179c90b8e4b8947d20f5c58d8d67e 206 Pfam PF00072 Response regulator receiver domain 4 116 2.0E-28 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK77_RS14255 742179c90b8e4b8947d20f5c58d8d67e 206 Pfam PF00196 Bacterial regulatory proteins, luxR family 144 198 1.3E-17 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK77_RS14255 742179c90b8e4b8947d20f5c58d8d67e 206 Gene3D G3DSA:3.40.50.2300 1 120 4.7E-38 T 06-07-2017 CAK77_RS14255 742179c90b8e4b8947d20f5c58d8d67e 206 ProSitePatterns PS00622 LuxR-type HTH domain signature. 159 186 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK77_RS14255 742179c90b8e4b8947d20f5c58d8d67e 206 SUPERFAMILY SSF52172 1 134 4.98E-35 T 06-07-2017 IPR011006 CheY-like superfamily CAK77_RS02565 1571dcec03d048a03f6856e8627ffdc3 519 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 341 508 7.7E-22 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CAK77_RS02565 1571dcec03d048a03f6856e8627ffdc3 519 Pfam PF00672 HAMP domain 241 307 2.9E-12 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAK77_RS02565 1571dcec03d048a03f6856e8627ffdc3 519 SMART SM00304 260 312 3.9E-10 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAK77_RS02565 1571dcec03d048a03f6856e8627ffdc3 519 Gene3D G3DSA:3.30.70.1230 339 513 1.7E-31 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CAK77_RS02565 1571dcec03d048a03f6856e8627ffdc3 519 SUPERFAMILY SSF55073 336 514 1.31E-43 T 06-07-2017 IPR029787 Nucleotide cyclase CAK77_RS02565 1571dcec03d048a03f6856e8627ffdc3 519 SMART SM00044 308 498 2.8E-7 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CAK77_RS02565 1571dcec03d048a03f6856e8627ffdc3 519 SUPERFAMILY SSF158472 261 309 3.66E-7 T 06-07-2017 CAK77_RS00545 d9b81c88f861791edf4f667c71607691 306 Pfam PF07859 alpha/beta hydrolase fold 77 282 5.6E-73 T 06-07-2017 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CAK77_RS00545 d9b81c88f861791edf4f667c71607691 306 SUPERFAMILY SSF53474 16 299 2.44E-77 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS00545 d9b81c88f861791edf4f667c71607691 306 Gene3D G3DSA:3.40.50.1820 2 305 6.0E-101 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS21180 9ae57b6707428f0e8b9e082064f00e17 693 TIGRFAM TIGR00651 pta: phosphate acetyltransferase 383 684 2.8E-125 T 06-07-2017 IPR004614 Phosphate acetyltransferase GO:0016407 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CAK77_RS21180 9ae57b6707428f0e8b9e082064f00e17 693 Gene3D G3DSA:3.40.1390.20 206 343 5.6E-30 T 06-07-2017 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like CAK77_RS21180 9ae57b6707428f0e8b9e082064f00e17 693 SUPERFAMILY SSF75138 204 328 3.57E-20 T 06-07-2017 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like CAK77_RS21180 9ae57b6707428f0e8b9e082064f00e17 693 Gene3D G3DSA:3.40.50.300 8 205 7.5E-9 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS21180 9ae57b6707428f0e8b9e082064f00e17 693 SUPERFAMILY SSF52540 8 211 4.78E-17 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS21180 9ae57b6707428f0e8b9e082064f00e17 693 Pfam PF07085 DRTGG domain 209 322 1.3E-24 T 06-07-2017 IPR010766 DRTGG KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CAK77_RS21180 9ae57b6707428f0e8b9e082064f00e17 693 Gene3D G3DSA:3.40.50.10750 502 660 1.4E-65 T 06-07-2017 CAK77_RS21180 9ae57b6707428f0e8b9e082064f00e17 693 Pfam PF13500 AAA domain 8 200 2.6E-22 T 06-07-2017 CAK77_RS21180 9ae57b6707428f0e8b9e082064f00e17 693 Pfam PF01515 Phosphate acetyl/butaryl transferase 367 684 1.1E-130 T 06-07-2017 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CAK77_RS21180 9ae57b6707428f0e8b9e082064f00e17 693 SUPERFAMILY SSF53659 368 688 1.56E-94 T 06-07-2017 CAK77_RS20000 5419b3da25ef921befb02d48e22aaff5 443 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 2 418 26.154 T 06-07-2017 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CAK77_RS20000 5419b3da25ef921befb02d48e22aaff5 443 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 99 122 - T 06-07-2017 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CAK77_RS20000 5419b3da25ef921befb02d48e22aaff5 443 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 322 420 2.0E-20 T 06-07-2017 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CAK77_RS20000 5419b3da25ef921befb02d48e22aaff5 443 PIRSF PIRSF000445 1 432 2.1E-138 T 06-07-2017 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CAK77_RS20000 5419b3da25ef921befb02d48e22aaff5 443 SUPERFAMILY SSF69075 321 421 1.07E-15 T 06-07-2017 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CAK77_RS20000 5419b3da25ef921befb02d48e22aaff5 443 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 7 156 2.0E-43 T 06-07-2017 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CAK77_RS20000 5419b3da25ef921befb02d48e22aaff5 443 SUPERFAMILY SSF69742 3 158 3.66E-43 T 06-07-2017 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CAK77_RS20000 5419b3da25ef921befb02d48e22aaff5 443 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 172 307 2.8E-29 T 06-07-2017 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase CAK77_RS20000 5419b3da25ef921befb02d48e22aaff5 443 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 3 421 9.0E-136 T 06-07-2017 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CAK77_RS20000 5419b3da25ef921befb02d48e22aaff5 443 Gene3D G3DSA:3.40.50.720 164 305 3.1E-30 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS20000 5419b3da25ef921befb02d48e22aaff5 443 SUPERFAMILY SSF51735 163 304 1.64E-25 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS01755 2346967d2f230493c9890ad1f32061fc 351 Pfam PF13432 Tetratricopeptide repeat 96 144 0.0013 T 06-07-2017 CAK77_RS01755 2346967d2f230493c9890ad1f32061fc 351 Gene3D G3DSA:1.25.40.10 21 202 6.8E-25 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK77_RS01755 2346967d2f230493c9890ad1f32061fc 351 SUPERFAMILY SSF48452 19 201 5.61E-21 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK77_RS01755 2346967d2f230493c9890ad1f32061fc 351 SMART SM00028 110 143 0.071 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAK77_RS01755 2346967d2f230493c9890ad1f32061fc 351 SMART SM00028 144 177 130.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAK77_RS16500 b709466a04a934063175eeb269fc3640 348 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 58 302 6.4E-28 T 06-07-2017 IPR018713 Domain of unknown function DUF2236 CAK77_RS16175 31c43cb7cd964a58d3e36ec3e2516dba 835 Gene3D G3DSA:3.40.50.620 231 356 6.3E-18 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS16175 31c43cb7cd964a58d3e36ec3e2516dba 835 Gene3D G3DSA:1.20.120.620 381 481 2.1E-18 T 06-07-2017 CAK77_RS16175 31c43cb7cd964a58d3e36ec3e2516dba 835 Gene3D G3DSA:3.40.50.300 7 215 3.6E-98 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS16175 31c43cb7cd964a58d3e36ec3e2516dba 835 PRINTS PR00344 Bacterial sensor protein C-terminal signature 811 824 7.2E-8 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK77_RS16175 31c43cb7cd964a58d3e36ec3e2516dba 835 PRINTS PR00344 Bacterial sensor protein C-terminal signature 787 805 7.2E-8 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK77_RS16175 31c43cb7cd964a58d3e36ec3e2516dba 835 PRINTS PR00344 Bacterial sensor protein C-terminal signature 754 768 7.2E-8 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK77_RS16175 31c43cb7cd964a58d3e36ec3e2516dba 835 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 720 825 1.9E-16 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS16175 31c43cb7cd964a58d3e36ec3e2516dba 835 Gene3D G3DSA:1.10.287.130 602 674 1.4E-17 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK77_RS16175 31c43cb7cd964a58d3e36ec3e2516dba 835 Gene3D G3DSA:3.30.565.10 683 826 4.7E-30 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS16175 31c43cb7cd964a58d3e36ec3e2516dba 835 SUPERFAMILY SSF47384 601 678 8.44E-15 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK77_RS16175 31c43cb7cd964a58d3e36ec3e2516dba 835 Pfam PF00582 Universal stress protein family 237 351 9.0E-9 T 06-07-2017 IPR006016 UspA GO:0006950 CAK77_RS16175 31c43cb7cd964a58d3e36ec3e2516dba 835 SMART SM00388 610 678 2.5E-16 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK77_RS16175 31c43cb7cd964a58d3e36ec3e2516dba 835 Pfam PF00512 His Kinase A (phospho-acceptor) domain 611 678 2.1E-14 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK77_RS16175 31c43cb7cd964a58d3e36ec3e2516dba 835 SUPERFAMILY SSF52402 237 358 1.37E-14 T 06-07-2017 CAK77_RS16175 31c43cb7cd964a58d3e36ec3e2516dba 835 Pfam PF02702 Osmosensitive K+ channel His kinase sensor domain 8 216 1.0E-97 T 06-07-2017 IPR003852 Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal GO:0000155|GO:0000160|GO:0004673|GO:0016020 CAK77_RS16175 31c43cb7cd964a58d3e36ec3e2516dba 835 SMART SM00387 719 827 3.2E-24 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS16175 31c43cb7cd964a58d3e36ec3e2516dba 835 Pfam PF13493 Domain of unknown function (DUF4118) 384 490 1.9E-23 T 06-07-2017 IPR025201 Sensor protein KdpD, transmembrane domain CAK77_RS16175 31c43cb7cd964a58d3e36ec3e2516dba 835 SUPERFAMILY SSF55874 701 826 3.67E-30 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS09780 0ef83a56cb77b572184944eb50dcdb86 239 Gene3D G3DSA:3.20.20.10 2 236 3.0E-78 T 06-07-2017 IPR029066 PLP-binding barrel CAK77_RS09780 0ef83a56cb77b572184944eb50dcdb86 239 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 13 234 2.0E-45 T 06-07-2017 IPR011078 Uncharacterised protein family UPF0001 CAK77_RS09780 0ef83a56cb77b572184944eb50dcdb86 239 SUPERFAMILY SSF51419 4 232 6.98E-65 T 06-07-2017 IPR029066 PLP-binding barrel CAK77_RS09780 0ef83a56cb77b572184944eb50dcdb86 239 Pfam PF01168 Alanine racemase, N-terminal domain 11 235 8.3E-19 T 06-07-2017 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAK77_RS09780 0ef83a56cb77b572184944eb50dcdb86 239 ProSitePatterns PS01211 Uncharacterized protein family UPF0001 signature. 82 96 - T 06-07-2017 IPR011078 Uncharacterised protein family UPF0001 CAK77_RS09780 0ef83a56cb77b572184944eb50dcdb86 239 PIRSF PIRSF004848 1 239 9.4E-69 T 06-07-2017 IPR011078 Uncharacterised protein family UPF0001 CAK77_RS21665 d8e74ff9883b84c3e4ca42532f8d51d1 835 Gene3D G3DSA:3.40.720.10 94 545 1.8E-103 T 06-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CAK77_RS21665 d8e74ff9883b84c3e4ca42532f8d51d1 835 Pfam PF00884 Sulfatase 95 517 5.2E-83 T 06-07-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 CAK77_RS21665 d8e74ff9883b84c3e4ca42532f8d51d1 835 ProSitePatterns PS00523 Sulfatases signature 1. 139 151 - T 06-07-2017 IPR024607 Sulfatase, conserved site CAK77_RS21665 d8e74ff9883b84c3e4ca42532f8d51d1 835 Gene3D G3DSA:3.30.1120.10 549 634 1.8E-18 T 06-07-2017 CAK77_RS21665 d8e74ff9883b84c3e4ca42532f8d51d1 835 SUPERFAMILY SSF53649 95 624 9.89E-124 T 06-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CAK77_RS09295 9b642406ebf9e28e63255882345dbcd2 509 Gene3D G3DSA:3.40.50.1820 194 317 1.5E-56 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS09295 9b642406ebf9e28e63255882345dbcd2 509 Gene3D G3DSA:3.40.50.1820 376 497 1.5E-56 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS09295 9b642406ebf9e28e63255882345dbcd2 509 Gene3D G3DSA:3.40.50.1820 66 148 1.5E-56 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS09295 9b642406ebf9e28e63255882345dbcd2 509 SUPERFAMILY SSF53474 371 490 3.88E-22 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS09295 9b642406ebf9e28e63255882345dbcd2 509 SUPERFAMILY SSF53474 73 161 3.88E-22 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS09295 9b642406ebf9e28e63255882345dbcd2 509 SUPERFAMILY SSF53474 202 269 3.88E-22 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS09295 9b642406ebf9e28e63255882345dbcd2 509 Pfam PF00561 alpha/beta hydrolase fold 98 485 3.6E-67 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS12185 a3647a9b9ad9151c1e7b7b6c8a4b9686 232 SMART SM00419 165 215 2.4E-7 T 06-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CAK77_RS12185 a3647a9b9ad9151c1e7b7b6c8a4b9686 232 Gene3D G3DSA:1.10.10.10 146 220 1.7E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS12185 a3647a9b9ad9151c1e7b7b6c8a4b9686 232 SMART SM00100 10 131 1.5E-17 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain CAK77_RS12185 a3647a9b9ad9151c1e7b7b6c8a4b9686 232 Pfam PF13545 Crp-like helix-turn-helix domain 148 219 5.8E-15 T 06-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CAK77_RS12185 a3647a9b9ad9151c1e7b7b6c8a4b9686 232 Pfam PF00027 Cyclic nucleotide-binding domain 29 113 4.3E-21 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain CAK77_RS12185 a3647a9b9ad9151c1e7b7b6c8a4b9686 232 SUPERFAMILY SSF46785 146 219 7.88E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS12185 a3647a9b9ad9151c1e7b7b6c8a4b9686 232 Gene3D G3DSA:2.60.120.10 7 140 2.5E-31 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK77_RS12185 a3647a9b9ad9151c1e7b7b6c8a4b9686 232 SUPERFAMILY SSF51206 5 140 6.02E-30 T 06-07-2017 IPR018490 Cyclic nucleotide-binding-like CAK77_RS02550 df0d962fffd4921882684269c285e61a 67 SUPERFAMILY SSF50249 1 66 1.56E-25 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS02550 df0d962fffd4921882684269c285e61a 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 06-07-2017 IPR019844 Cold-shock conserved site CAK77_RS02550 df0d962fffd4921882684269c285e61a 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 66 6.2E-32 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAK77_RS02550 df0d962fffd4921882684269c285e61a 67 SMART SM00357 3 67 3.0E-31 T 06-07-2017 IPR011129 Cold shock protein GO:0003676 CAK77_RS02550 df0d962fffd4921882684269c285e61a 67 Gene3D G3DSA:2.40.50.140 1 65 4.3E-32 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS02550 df0d962fffd4921882684269c285e61a 67 PRINTS PR00050 Cold shock protein signature 4 19 2.4E-16 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAK77_RS02550 df0d962fffd4921882684269c285e61a 67 PRINTS PR00050 Cold shock protein signature 25 34 2.4E-16 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAK77_RS02550 df0d962fffd4921882684269c285e61a 67 PRINTS PR00050 Cold shock protein signature 40 58 2.4E-16 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAK77_RS02550 df0d962fffd4921882684269c285e61a 67 PIRSF PIRSF002599 1 67 4.3E-25 T 06-07-2017 IPR012156 Cold shock, CspA GO:0003676 CAK77_RS22060 ea260afae058fa1186b770b63085fd6a 248 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 14 219 8.8E-45 T 06-07-2017 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK77_RS22060 ea260afae058fa1186b770b63085fd6a 248 Gene3D G3DSA:3.10.20.30 5 95 1.2E-29 T 06-07-2017 IPR012675 Beta-grasp domain CAK77_RS22060 ea260afae058fa1186b770b63085fd6a 248 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 7 105 2.3E-27 T 06-07-2017 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK77_RS22060 ea260afae058fa1186b770b63085fd6a 248 Gene3D G3DSA:1.10.1060.10 96 239 2.2E-19 T 06-07-2017 CAK77_RS22060 ea260afae058fa1186b770b63085fd6a 248 Pfam PF13183 4Fe-4S dicluster domain 140 216 1.1E-13 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CAK77_RS22060 ea260afae058fa1186b770b63085fd6a 248 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 53 61 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CAK77_RS22060 ea260afae058fa1186b770b63085fd6a 248 SUPERFAMILY SSF46548 123 228 2.96E-18 T 06-07-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 CAK77_RS22060 ea260afae058fa1186b770b63085fd6a 248 SUPERFAMILY SSF54292 5 103 2.88E-23 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK77_RS20020 cf3b7f0d9a04f9d99b04e52c1cc2f776 334 SUPERFAMILY SSF46689 281 331 2.73E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS20020 cf3b7f0d9a04f9d99b04e52c1cc2f776 334 Gene3D G3DSA:1.10.10.60 280 330 3.0E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS20020 cf3b7f0d9a04f9d99b04e52c1cc2f776 334 SMART SM00342 246 328 1.3E-26 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK77_RS20020 cf3b7f0d9a04f9d99b04e52c1cc2f776 334 Pfam PF12833 Helix-turn-helix domain 253 329 9.0E-20 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK77_RS20020 cf3b7f0d9a04f9d99b04e52c1cc2f776 334 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 20 204 5.1E-39 T 06-07-2017 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal CAK77_RS01420 55ea49327af75d88600bb9bf9965b305 354 SUPERFAMILY SSF50249 200 337 1.2E-14 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS01420 55ea49327af75d88600bb9bf9965b305 354 Gene3D G3DSA:3.30.1490.70 156 198 2.9E-10 T 06-07-2017 CAK77_RS01420 55ea49327af75d88600bb9bf9965b305 354 Gene3D G3DSA:3.30.1490.70 3 31 2.9E-10 T 06-07-2017 CAK77_RS01420 55ea49327af75d88600bb9bf9965b305 354 Gene3D G3DSA:2.40.50.140 200 335 5.9E-14 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS01420 55ea49327af75d88600bb9bf9965b305 354 SUPERFAMILY SSF56091 6 197 1.94E-41 T 06-07-2017 CAK77_RS01420 55ea49327af75d88600bb9bf9965b305 354 Pfam PF04679 ATP dependent DNA ligase C terminal region 217 328 1.1E-14 T 06-07-2017 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 CAK77_RS01420 55ea49327af75d88600bb9bf9965b305 354 Pfam PF01068 ATP dependent DNA ligase domain 11 197 6.9E-36 T 06-07-2017 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 CAK77_RS01420 55ea49327af75d88600bb9bf9965b305 354 Gene3D G3DSA:3.30.470.30 32 145 1.2E-26 T 06-07-2017 CAK77_RS04350 cacb3c23e23954b7da3fb23587be1318 331 SUPERFAMILY SSF51679 7 329 2.09E-74 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS04350 cacb3c23e23954b7da3fb23587be1318 331 TIGRFAM TIGR03560 F420_Rv1855c: probable F420-dependent oxidoreductase, Rv1855c family 24 242 1.7E-81 T 06-07-2017 IPR019952 F420-dependent oxidoreductase-predicted, Rv1855c CAK77_RS04350 cacb3c23e23954b7da3fb23587be1318 331 Pfam PF00296 Luciferase-like monooxygenase 9 304 1.8E-49 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS04350 cacb3c23e23954b7da3fb23587be1318 331 Gene3D G3DSA:3.20.20.30 6 329 2.1E-80 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS13915 2436c90cb9a351757cf36d9dabec4d20 265 Gene3D G3DSA:3.40.50.150 8 185 2.3E-28 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS13915 2436c90cb9a351757cf36d9dabec4d20 265 SUPERFAMILY SSF53335 13 210 3.95E-31 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS13915 2436c90cb9a351757cf36d9dabec4d20 265 Gene3D G3DSA:1.10.150.290 187 242 2.5E-26 T 06-07-2017 IPR023149 Trans-aconitate 2-methyltransferase, C-terminal GO:0030798 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CAK77_RS13915 2436c90cb9a351757cf36d9dabec4d20 265 Pfam PF13649 Methyltransferase domain 40 129 1.5E-13 T 06-07-2017 CAK77_RS15865 3a472925525f791ab09bbc799050715a 241 PIRSF PIRSF005650 6 241 1.2E-85 T 06-07-2017 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 CAK77_RS15865 3a472925525f791ab09bbc799050715a 241 SUPERFAMILY SSF53633 9 241 3.53E-71 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase CAK77_RS15865 3a472925525f791ab09bbc799050715a 241 Gene3D G3DSA:3.40.1160.10 5 241 4.6E-87 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase CAK77_RS15865 3a472925525f791ab09bbc799050715a 241 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 10 240 1.6E-86 T 06-07-2017 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 CAK77_RS15865 3a472925525f791ab09bbc799050715a 241 Hamap MF_01220_B Uridylate kinase [pyrH]. 8 240 42.004 T 06-07-2017 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 CAK77_RS15865 3a472925525f791ab09bbc799050715a 241 Pfam PF00696 Amino acid kinase family 11 219 1.9E-31 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase CAK77_RS00500 0cbd599584d4e44ae3186a5a2c6ac912 401 SUPERFAMILY SSF103473 12 374 2.35E-32 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK77_RS00500 0cbd599584d4e44ae3186a5a2c6ac912 401 Gene3D G3DSA:1.20.1250.20 192 376 1.3E-4 T 06-07-2017 CAK77_RS00500 0cbd599584d4e44ae3186a5a2c6ac912 401 Gene3D G3DSA:1.20.1250.20 12 177 1.3E-19 T 06-07-2017 CAK77_RS00500 0cbd599584d4e44ae3186a5a2c6ac912 401 ProSitePatterns PS00216 Sugar transport proteins signature 1. 46 62 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CAK77_RS00500 0cbd599584d4e44ae3186a5a2c6ac912 401 Pfam PF07690 Major Facilitator Superfamily 13 335 3.8E-24 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK77_RS21175 511b590374d912a8e0b83c27aa0b40db 372 Gene3D G3DSA:3.30.420.40 7 182 4.8E-12 T 06-07-2017 CAK77_RS21175 511b590374d912a8e0b83c27aa0b40db 372 SUPERFAMILY SSF53067 135 370 9.07E-79 T 06-07-2017 CAK77_RS21175 511b590374d912a8e0b83c27aa0b40db 372 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 7 18 - T 06-07-2017 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CAK77_RS21175 511b590374d912a8e0b83c27aa0b40db 372 TIGRFAM TIGR00016 ackA: acetate kinase 6 369 8.9E-123 T 06-07-2017 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CAK77_RS21175 511b590374d912a8e0b83c27aa0b40db 372 Pfam PF00871 Acetokinase family 7 366 1.8E-131 T 06-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CAK77_RS21175 511b590374d912a8e0b83c27aa0b40db 372 Gene3D G3DSA:3.30.420.40 183 370 1.0E-72 T 06-07-2017 CAK77_RS21175 511b590374d912a8e0b83c27aa0b40db 372 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 181 198 - T 06-07-2017 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CAK77_RS21175 511b590374d912a8e0b83c27aa0b40db 372 PIRSF PIRSF000722 4 372 9.9E-126 T 06-07-2017 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CAK77_RS21175 511b590374d912a8e0b83c27aa0b40db 372 SUPERFAMILY SSF53067 7 173 6.47E-60 T 06-07-2017 CAK77_RS21175 511b590374d912a8e0b83c27aa0b40db 372 PRINTS PR00471 Acetate kinase family signature 7 18 2.3E-43 T 06-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CAK77_RS21175 511b590374d912a8e0b83c27aa0b40db 372 PRINTS PR00471 Acetate kinase family signature 276 289 2.3E-43 T 06-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CAK77_RS21175 511b590374d912a8e0b83c27aa0b40db 372 PRINTS PR00471 Acetate kinase family signature 181 202 2.3E-43 T 06-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CAK77_RS21175 511b590374d912a8e0b83c27aa0b40db 372 PRINTS PR00471 Acetate kinase family signature 298 314 2.3E-43 T 06-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CAK77_RS21175 511b590374d912a8e0b83c27aa0b40db 372 PRINTS PR00471 Acetate kinase family signature 151 164 2.3E-43 T 06-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CAK77_RS21175 511b590374d912a8e0b83c27aa0b40db 372 PRINTS PR00471 Acetate kinase family signature 353 365 2.3E-43 T 06-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CAK77_RS21175 511b590374d912a8e0b83c27aa0b40db 372 Hamap MF_00020 Acetate kinase [ackA]. 1 372 158.293 T 06-07-2017 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CAK77_RS17975 7f69620ee82ca8947577cbeb1221c1ec 282 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 2 280 4.0E-88 T 06-07-2017 IPR005913 dTDP-4-dehydrorhamnose reductase family Reactome: R-HSA-156581 CAK77_RS17975 7f69620ee82ca8947577cbeb1221c1ec 282 SUPERFAMILY SSF51735 3 280 1.23E-75 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS17975 7f69620ee82ca8947577cbeb1221c1ec 282 Pfam PF04321 RmlD substrate binding domain 2 280 1.2E-90 T 06-07-2017 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581 CAK77_RS17975 7f69620ee82ca8947577cbeb1221c1ec 282 Gene3D G3DSA:3.40.50.720 3 229 2.8E-47 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS09670 abea98ea6da24ac50d854c207e97a272 146 SUPERFAMILY SSF55961 5 144 1.45E-18 T 06-07-2017 CAK77_RS09670 abea98ea6da24ac50d854c207e97a272 146 Gene3D G3DSA:3.30.530.20 5 144 4.3E-15 T 06-07-2017 IPR023393 START-like domain CAK77_RS09670 abea98ea6da24ac50d854c207e97a272 146 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 18 120 2.9E-7 T 06-07-2017 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CAK77_RS20960 22a6dc3cf0ab743542003e74d7ddc67a 632 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 459 632 34.139 T 06-07-2017 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 CAK77_RS20960 22a6dc3cf0ab743542003e74d7ddc67a 632 Gene3D G3DSA:2.40.30.10 345 435 1.2E-9 T 06-07-2017 CAK77_RS20960 22a6dc3cf0ab743542003e74d7ddc67a 632 SUPERFAMILY SSF52540 10 220 3.31E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS20960 22a6dc3cf0ab743542003e74d7ddc67a 632 Gene3D G3DSA:2.40.30.10 230 344 3.9E-15 T 06-07-2017 CAK77_RS20960 22a6dc3cf0ab743542003e74d7ddc67a 632 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 15 198 1.1E-14 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 CAK77_RS20960 22a6dc3cf0ab743542003e74d7ddc67a 632 SUPERFAMILY SSF50465 334 435 1.01E-29 T 06-07-2017 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal CAK77_RS20960 22a6dc3cf0ab743542003e74d7ddc67a 632 SUPERFAMILY SSF52540 459 630 1.49E-36 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS20960 22a6dc3cf0ab743542003e74d7ddc67a 632 SUPERFAMILY SSF50447 230 329 1.06E-15 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain CAK77_RS20960 22a6dc3cf0ab743542003e74d7ddc67a 632 Gene3D G3DSA:3.40.50.300 443 628 3.6E-78 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS20960 22a6dc3cf0ab743542003e74d7ddc67a 632 PRINTS PR00315 GTP-binding elongation factor signature 16 29 1.4E-13 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAK77_RS20960 22a6dc3cf0ab743542003e74d7ddc67a 632 PRINTS PR00315 GTP-binding elongation factor signature 75 83 1.4E-13 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAK77_RS20960 22a6dc3cf0ab743542003e74d7ddc67a 632 PRINTS PR00315 GTP-binding elongation factor signature 111 122 1.4E-13 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAK77_RS20960 22a6dc3cf0ab743542003e74d7ddc67a 632 PRINTS PR00315 GTP-binding elongation factor signature 95 105 1.4E-13 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAK77_RS20960 22a6dc3cf0ab743542003e74d7ddc67a 632 PRINTS PR00315 GTP-binding elongation factor signature 148 157 1.4E-13 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAK77_RS20960 22a6dc3cf0ab743542003e74d7ddc67a 632 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 68 83 - T 06-07-2017 IPR031157 Tr-type G domain, conserved site CAK77_RS20960 22a6dc3cf0ab743542003e74d7ddc67a 632 TIGRFAM TIGR02034 CysN: sulfate adenylyltransferase, large subunit 16 435 3.5E-161 T 06-07-2017 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 CAK77_RS20960 22a6dc3cf0ab743542003e74d7ddc67a 632 Gene3D G3DSA:3.40.50.300 8 219 2.6E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS20960 22a6dc3cf0ab743542003e74d7ddc67a 632 Pfam PF01583 Adenylylsulphate kinase 461 615 1.2E-67 T 06-07-2017 CAK77_RS20960 22a6dc3cf0ab743542003e74d7ddc67a 632 Pfam PF00009 Elongation factor Tu GTP binding domain 14 198 6.4E-43 T 06-07-2017 CAK77_RS20960 22a6dc3cf0ab743542003e74d7ddc67a 632 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 447 628 5.3E-69 T 06-07-2017 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 CAK77_RS08215 f2ba56bae7c79ff44698f7b1af91679c 103 TIGRFAM TIGR00061 L21: ribosomal protein bL21 4 102 2.0E-24 T 06-07-2017 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS08215 f2ba56bae7c79ff44698f7b1af91679c 103 Pfam PF00829 Ribosomal prokaryotic L21 protein 4 102 1.0E-32 T 06-07-2017 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS08215 f2ba56bae7c79ff44698f7b1af91679c 103 SUPERFAMILY SSF141091 4 102 4.84E-31 T 06-07-2017 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS08215 f2ba56bae7c79ff44698f7b1af91679c 103 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 3 103 19.426 T 06-07-2017 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS08215 f2ba56bae7c79ff44698f7b1af91679c 103 ProSitePatterns PS01169 Ribosomal protein L21 signature. 73 95 - T 06-07-2017 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS18940 0935c64ea6a3a1faaaae8f0b0b065430 137 Gene3D G3DSA:3.30.420.100 41 137 1.2E-33 T 06-07-2017 CAK77_RS18940 0935c64ea6a3a1faaaae8f0b0b065430 137 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 23 137 5.1E-45 T 06-07-2017 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS18940 0935c64ea6a3a1faaaae8f0b0b065430 137 SUPERFAMILY SSF53137 24 135 7.41E-45 T 06-07-2017 CAK77_RS18940 0935c64ea6a3a1faaaae8f0b0b065430 137 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 23 137 25.912 T 06-07-2017 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS18940 0935c64ea6a3a1faaaae8f0b0b065430 137 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 26 137 1.5E-35 T 06-07-2017 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS24435 134203974f87078f8014af909364c3a1 791 SUPERFAMILY SSF53649 47 576 2.18E-127 T 06-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CAK77_RS24435 134203974f87078f8014af909364c3a1 791 ProSitePatterns PS00523 Sulfatases signature 1. 91 103 - T 06-07-2017 IPR024607 Sulfatase, conserved site CAK77_RS24435 134203974f87078f8014af909364c3a1 791 Pfam PF00884 Sulfatase 47 464 2.6E-93 T 06-07-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 CAK77_RS24435 134203974f87078f8014af909364c3a1 791 Gene3D G3DSA:3.30.1120.10 494 584 1.1E-17 T 06-07-2017 CAK77_RS24435 134203974f87078f8014af909364c3a1 791 SUPERFAMILY SSF49899 640 765 2.9E-6 T 06-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain CAK77_RS24435 134203974f87078f8014af909364c3a1 791 Gene3D G3DSA:3.40.720.10 46 488 1.0E-105 T 06-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CAK77_RS17340 134203974f87078f8014af909364c3a1 791 SUPERFAMILY SSF53649 47 576 2.18E-127 T 06-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CAK77_RS17340 134203974f87078f8014af909364c3a1 791 ProSitePatterns PS00523 Sulfatases signature 1. 91 103 - T 06-07-2017 IPR024607 Sulfatase, conserved site CAK77_RS17340 134203974f87078f8014af909364c3a1 791 Pfam PF00884 Sulfatase 47 464 2.6E-93 T 06-07-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 CAK77_RS17340 134203974f87078f8014af909364c3a1 791 Gene3D G3DSA:3.30.1120.10 494 584 1.1E-17 T 06-07-2017 CAK77_RS17340 134203974f87078f8014af909364c3a1 791 SUPERFAMILY SSF49899 640 765 2.9E-6 T 06-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain CAK77_RS17340 134203974f87078f8014af909364c3a1 791 Gene3D G3DSA:3.40.720.10 46 488 1.0E-105 T 06-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CAK77_RS16050 12966be0a6f26d010368da990bdde0f3 242 Gene3D G3DSA:3.40.1280.10 1 160 3.7E-65 T 06-07-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CAK77_RS16050 12966be0a6f26d010368da990bdde0f3 242 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 242 96.028 T 06-07-2017 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CAK77_RS16050 12966be0a6f26d010368da990bdde0f3 242 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 22 224 1.3E-69 T 06-07-2017 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CAK77_RS16050 12966be0a6f26d010368da990bdde0f3 242 PIRSF PIRSF000386 1 232 3.1E-88 T 06-07-2017 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CAK77_RS16050 12966be0a6f26d010368da990bdde0f3 242 Gene3D G3DSA:1.10.1270.20 161 227 6.8E-27 T 06-07-2017 IPR023148 tRNA (guanine-N1-)-methyltransferase, C-terminal GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CAK77_RS16050 12966be0a6f26d010368da990bdde0f3 242 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 227 7.9E-74 T 06-07-2017 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CAK77_RS16050 12966be0a6f26d010368da990bdde0f3 242 SUPERFAMILY SSF75217 1 228 8.5E-84 T 06-07-2017 IPR029028 Alpha/beta knot methyltransferases CAK77_RS10225 40f433e768cd7195380201e2eff57f4a 353 TIGRFAM TIGR01036 pyrD_sub2: dihydroorotate dehydrogenase (fumarate) 3 352 6.7E-133 T 06-07-2017 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CAK77_RS10225 40f433e768cd7195380201e2eff57f4a 353 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 85 104 - T 06-07-2017 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 CAK77_RS10225 40f433e768cd7195380201e2eff57f4a 353 Hamap MF_00225 Dihydroorotate dehydrogenase (quinone) [pyrD]. 2 333 45.081 T 06-07-2017 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CAK77_RS10225 40f433e768cd7195380201e2eff57f4a 353 Pfam PF01180 Dihydroorotate dehydrogenase 50 337 9.9E-92 T 06-07-2017 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 CAK77_RS10225 40f433e768cd7195380201e2eff57f4a 353 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 289 309 - T 06-07-2017 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 CAK77_RS10225 40f433e768cd7195380201e2eff57f4a 353 PIRSF PIRSF000164 23 353 1.6E-99 T 06-07-2017 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 CAK77_RS10225 40f433e768cd7195380201e2eff57f4a 353 Gene3D G3DSA:3.20.20.70 2 352 1.9E-116 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK77_RS10225 40f433e768cd7195380201e2eff57f4a 353 SUPERFAMILY SSF51395 3 352 8.25E-97 T 06-07-2017 CAK77_RS10915 2e554ea61c3d3ceb98a28bc3c8e48532 247 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 52 68 5.1E-10 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK77_RS10915 2e554ea61c3d3ceb98a28bc3c8e48532 247 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 38 52 5.1E-10 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK77_RS10915 2e554ea61c3d3ceb98a28bc3c8e48532 247 SMART SM00345 20 78 5.5E-16 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK77_RS10915 2e554ea61c3d3ceb98a28bc3c8e48532 247 Gene3D G3DSA:1.10.10.10 20 76 4.7E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS10915 2e554ea61c3d3ceb98a28bc3c8e48532 247 SUPERFAMILY SSF46785 14 82 2.48E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS10915 2e554ea61c3d3ceb98a28bc3c8e48532 247 Pfam PF00392 Bacterial regulatory proteins, gntR family 20 78 3.1E-16 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK77_RS10915 2e554ea61c3d3ceb98a28bc3c8e48532 247 SUPERFAMILY SSF64288 66 242 2.04E-37 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CAK77_RS10915 2e554ea61c3d3ceb98a28bc3c8e48532 247 Pfam PF07702 UTRA domain 102 237 3.3E-33 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CAK77_RS10915 2e554ea61c3d3ceb98a28bc3c8e48532 247 Gene3D G3DSA:3.40.1410.10 77 242 1.1E-37 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CAK77_RS10915 2e554ea61c3d3ceb98a28bc3c8e48532 247 SMART SM00866 98 238 3.4E-26 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CAK77_RS12800 4216574f9e8c6e3f78bc62e5979dfc90 225 Pfam PF01545 Cation efflux family 22 192 6.6E-9 T 06-07-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CAK77_RS12800 4216574f9e8c6e3f78bc62e5979dfc90 225 SUPERFAMILY SSF161111 13 196 4.32E-26 T 06-07-2017 CAK77_RS12800 4216574f9e8c6e3f78bc62e5979dfc90 225 Gene3D G3DSA:1.20.1510.10 19 192 7.8E-15 T 06-07-2017 IPR027469 Cation efflux protein transmembrane domain CAK77_RS21690 f574145eb5c892e81ad7a5626e914b6c 222 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 65 7.2E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS21690 f574145eb5c892e81ad7a5626e914b6c 222 Gene3D G3DSA:1.10.357.10 12 183 5.6E-19 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS21690 f574145eb5c892e81ad7a5626e914b6c 222 SUPERFAMILY SSF46689 8 78 1.2E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS06375 e6e66d700d8ab0e9b2737e3ccd7d5474 505 Gene3D G3DSA:2.60.40.420 187 360 3.0E-36 T 06-07-2017 IPR008972 Cupredoxin CAK77_RS06375 e6e66d700d8ab0e9b2737e3ccd7d5474 505 ProSitePatterns PS00080 Multicopper oxidases signature 2. 487 498 - T 06-07-2017 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 CAK77_RS06375 e6e66d700d8ab0e9b2737e3ccd7d5474 505 Gene3D G3DSA:2.60.40.420 378 504 3.3E-41 T 06-07-2017 IPR008972 Cupredoxin CAK77_RS06375 e6e66d700d8ab0e9b2737e3ccd7d5474 505 SUPERFAMILY SSF49503 382 502 3.61E-36 T 06-07-2017 IPR008972 Cupredoxin CAK77_RS06375 e6e66d700d8ab0e9b2737e3ccd7d5474 505 Gene3D G3DSA:2.60.40.420 57 184 6.3E-32 T 06-07-2017 IPR008972 Cupredoxin CAK77_RS06375 e6e66d700d8ab0e9b2737e3ccd7d5474 505 Pfam PF07732 Multicopper oxidase 80 183 1.3E-31 T 06-07-2017 IPR011707 Multicopper oxidase, type 3 GO:0005507 CAK77_RS06375 e6e66d700d8ab0e9b2737e3ccd7d5474 505 SUPERFAMILY SSF49503 58 210 1.96E-34 T 06-07-2017 IPR008972 Cupredoxin CAK77_RS06375 e6e66d700d8ab0e9b2737e3ccd7d5474 505 Pfam PF00394 Multicopper oxidase 191 325 1.2E-16 T 06-07-2017 IPR001117 Multicopper oxidase, type 1 GO:0016491|GO:0055114 CAK77_RS06375 e6e66d700d8ab0e9b2737e3ccd7d5474 505 SUPERFAMILY SSF49503 187 327 7.55E-27 T 06-07-2017 IPR008972 Cupredoxin CAK77_RS06375 e6e66d700d8ab0e9b2737e3ccd7d5474 505 Pfam PF07731 Multicopper oxidase 403 502 1.1E-26 T 06-07-2017 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 CAK77_RS12810 c110972eb36347a58999515cd5fc6b8e 600 Gene3D G3DSA:2.30.40.10 9 78 1.5E-19 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK77_RS12810 c110972eb36347a58999515cd5fc6b8e 600 SUPERFAMILY SSF51556 372 503 3.27E-39 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK77_RS12810 c110972eb36347a58999515cd5fc6b8e 600 SUPERFAMILY SSF51556 65 324 3.27E-39 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK77_RS12810 c110972eb36347a58999515cd5fc6b8e 600 Pfam PF07969 Amidohydrolase family 54 242 6.4E-12 T 06-07-2017 IPR013108 Amidohydrolase 3 CAK77_RS12810 c110972eb36347a58999515cd5fc6b8e 600 Gene3D G3DSA:2.30.40.10 489 568 3.2E-12 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK77_RS12810 c110972eb36347a58999515cd5fc6b8e 600 SUPERFAMILY SSF51338 9 64 6.49E-19 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK77_RS12810 c110972eb36347a58999515cd5fc6b8e 600 SUPERFAMILY SSF51338 506 570 6.49E-19 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK77_RS12810 c110972eb36347a58999515cd5fc6b8e 600 Gene3D G3DSA:3.20.20.140 79 316 3.5E-78 T 06-07-2017 CAK77_RS12810 c110972eb36347a58999515cd5fc6b8e 600 Gene3D G3DSA:3.20.20.140 428 488 3.5E-78 T 06-07-2017 CAK77_RS20480 70f85321884eda8f27bf62f6eb54ee09 289 Pfam PF02353 Mycolic acid cyclopropane synthetase 4 285 1.1E-105 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS20480 70f85321884eda8f27bf62f6eb54ee09 289 SUPERFAMILY SSF53335 12 289 4.43E-66 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS20480 70f85321884eda8f27bf62f6eb54ee09 289 Gene3D G3DSA:3.40.50.150 7 288 8.5E-76 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS20480 70f85321884eda8f27bf62f6eb54ee09 289 PIRSF PIRSF003085 6 289 5.2E-94 T 06-07-2017 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 CAK77_RS00445 2bcd03a803068a0b67fa2f75599c2210 1301 Pfam PF07717 Oligonucleotide/oligosaccharide-binding (OB)-fold 623 704 1.3E-13 T 06-07-2017 IPR011709 Domain of unknown function DUF1605 CAK77_RS00445 2bcd03a803068a0b67fa2f75599c2210 1301 Pfam PF04408 Helicase associated domain (HA2) 477 563 4.2E-19 T 06-07-2017 IPR007502 Helicase-associated domain GO:0004386 CAK77_RS00445 2bcd03a803068a0b67fa2f75599c2210 1301 Gene3D G3DSA:3.40.50.300 68 224 1.7E-45 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS00445 2bcd03a803068a0b67fa2f75599c2210 1301 TIGRFAM TIGR01967 DEAH_box_HrpA: RNA helicase HrpA 11 1298 0.0 T 06-07-2017 IPR010222 RNA helicase HrpA GO:0004004 CAK77_RS00445 2bcd03a803068a0b67fa2f75599c2210 1301 Gene3D G3DSA:3.40.50.300 270 431 6.4E-14 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS00445 2bcd03a803068a0b67fa2f75599c2210 1301 SMART SM00487 66 250 1.9E-30 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain CAK77_RS00445 2bcd03a803068a0b67fa2f75599c2210 1301 SMART SM00382 83 395 4.8E-5 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS00445 2bcd03a803068a0b67fa2f75599c2210 1301 SUPERFAMILY SSF52540 71 255 6.09E-105 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS00445 2bcd03a803068a0b67fa2f75599c2210 1301 SUPERFAMILY SSF52540 282 579 6.09E-105 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS00445 2bcd03a803068a0b67fa2f75599c2210 1301 SMART SM00847 475 565 4.0E-36 T 06-07-2017 IPR007502 Helicase-associated domain GO:0004386 CAK77_RS00445 2bcd03a803068a0b67fa2f75599c2210 1301 Pfam PF11898 Domain of unknown function (DUF3418) 719 1298 2.3E-210 T 06-07-2017 IPR024590 RNA helicase HrpA, C-terminal CAK77_RS00445 2bcd03a803068a0b67fa2f75599c2210 1301 Pfam PF00271 Helicase conserved C-terminal domain 293 414 2.2E-9 T 06-07-2017 IPR001650 Helicase, C-terminal CAK77_RS00445 2bcd03a803068a0b67fa2f75599c2210 1301 SMART SM00490 315 415 6.6E-15 T 06-07-2017 IPR001650 Helicase, C-terminal CAK77_RS09730 f2fc93877699a57fa5f55403798e3579 515 Pfam PF08245 Mur ligase middle domain 127 334 2.5E-47 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAK77_RS09730 f2fc93877699a57fa5f55403798e3579 515 Gene3D G3DSA:3.40.1190.10 118 357 1.0E-77 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAK77_RS09730 f2fc93877699a57fa5f55403798e3579 515 Pfam PF02875 Mur ligase family, glutamate ligase domain 354 439 6.1E-23 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CAK77_RS09730 f2fc93877699a57fa5f55403798e3579 515 Gene3D G3DSA:3.90.190.20 358 500 8.1E-51 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CAK77_RS09730 f2fc93877699a57fa5f55403798e3579 515 SUPERFAMILY SSF53623 118 349 2.62E-69 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAK77_RS09730 f2fc93877699a57fa5f55403798e3579 515 SUPERFAMILY SSF53244 354 508 1.23E-45 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CAK77_RS09730 f2fc93877699a57fa5f55403798e3579 515 SUPERFAMILY SSF63418 18 118 1.29E-14 T 06-07-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CAK77_RS09730 f2fc93877699a57fa5f55403798e3579 515 Pfam PF01225 Mur ligase family, catalytic domain 38 113 2.6E-6 T 06-07-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CAK77_RS09730 f2fc93877699a57fa5f55403798e3579 515 Gene3D G3DSA:3.40.1390.10 22 116 2.2E-15 T 06-07-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CAK77_RS09730 f2fc93877699a57fa5f55403798e3579 515 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 19 507 31.709 T 06-07-2017 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 CAK77_RS09730 f2fc93877699a57fa5f55403798e3579 515 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 35 507 3.3E-150 T 06-07-2017 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 CAK77_RS24365 aaf52d8558d6bb61021e511004011c70 181 SUPERFAMILY SSF82708 128 179 2.55E-9 T 06-07-2017 IPR001374 R3H domain GO:0003676 CAK77_RS24365 aaf52d8558d6bb61021e511004011c70 181 SMART SM00393 102 181 2.2E-25 T 06-07-2017 IPR001374 R3H domain GO:0003676 CAK77_RS24365 aaf52d8558d6bb61021e511004011c70 181 Gene3D G3DSA:3.30.300.120 35 112 5.4E-24 T 06-07-2017 CAK77_RS24365 aaf52d8558d6bb61021e511004011c70 181 Pfam PF01424 R3H domain 123 178 8.5E-14 T 06-07-2017 IPR001374 R3H domain GO:0003676 CAK77_RS24365 aaf52d8558d6bb61021e511004011c70 181 Gene3D G3DSA:3.30.1370.50 113 179 4.3E-24 T 06-07-2017 IPR001374 R3H domain GO:0003676 CAK77_RS24365 aaf52d8558d6bb61021e511004011c70 181 Pfam PF13083 KH domain 41 107 6.6E-8 T 06-07-2017 CAK77_RS16320 b7286afb5466a093b264151eee54bf31 746 SMART SM00487 285 489 8.4E-31 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain CAK77_RS16320 b7286afb5466a093b264151eee54bf31 746 Pfam PF00270 DEAD/DEAH box helicase 310 465 3.1E-16 T 06-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CAK77_RS16320 b7286afb5466a093b264151eee54bf31 746 Gene3D G3DSA:2.40.50.140 55 139 5.7E-12 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS16320 b7286afb5466a093b264151eee54bf31 746 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 25 711 4.5E-215 T 06-07-2017 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 CAK77_RS16320 b7286afb5466a093b264151eee54bf31 746 Gene3D G3DSA:3.40.50.300 497 682 1.7E-42 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS16320 b7286afb5466a093b264151eee54bf31 746 SUPERFAMILY SSF50249 13 201 5.14E-18 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS16320 b7286afb5466a093b264151eee54bf31 746 Pfam PF00271 Helicase conserved C-terminal domain 559 634 6.8E-20 T 06-07-2017 IPR001650 Helicase, C-terminal CAK77_RS16320 b7286afb5466a093b264151eee54bf31 746 SUPERFAMILY SSF52540 419 642 2.22E-36 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS16320 b7286afb5466a093b264151eee54bf31 746 SUPERFAMILY SSF52540 205 482 2.77E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS16320 b7286afb5466a093b264151eee54bf31 746 Gene3D G3DSA:3.40.50.300 279 485 1.5E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS16320 b7286afb5466a093b264151eee54bf31 746 SMART SM00490 549 634 2.4E-25 T 06-07-2017 IPR001650 Helicase, C-terminal CAK77_RS00665 0149f4c5ec5da5fb3a474f2235edb892 416 SUPERFAMILY SSF48264 21 406 4.19E-78 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS00665 0149f4c5ec5da5fb3a474f2235edb892 416 Gene3D G3DSA:1.10.630.10 4 407 6.0E-105 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS00665 0149f4c5ec5da5fb3a474f2235edb892 416 Pfam PF00067 Cytochrome P450 288 376 1.6E-11 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS00665 0149f4c5ec5da5fb3a474f2235edb892 416 PRINTS PR00359 B-class P450 signature 330 345 7.7E-43 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS00665 0149f4c5ec5da5fb3a474f2235edb892 416 PRINTS PR00359 B-class P450 signature 361 372 7.7E-43 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS00665 0149f4c5ec5da5fb3a474f2235edb892 416 PRINTS PR00359 B-class P450 signature 352 361 7.7E-43 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS00665 0149f4c5ec5da5fb3a474f2235edb892 416 PRINTS PR00359 B-class P450 signature 103 114 7.7E-43 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS00665 0149f4c5ec5da5fb3a474f2235edb892 416 PRINTS PR00359 B-class P450 signature 166 181 7.7E-43 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS00665 0149f4c5ec5da5fb3a474f2235edb892 416 PRINTS PR00359 B-class P450 signature 206 228 7.7E-43 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS00665 0149f4c5ec5da5fb3a474f2235edb892 416 PRINTS PR00359 B-class P450 signature 285 296 7.7E-43 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS00665 0149f4c5ec5da5fb3a474f2235edb892 416 PRINTS PR00359 B-class P450 signature 149 165 7.7E-43 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS00665 0149f4c5ec5da5fb3a474f2235edb892 416 PRINTS PR00359 B-class P450 signature 302 329 7.7E-43 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS19485 b65182dba07759993431b089b6cba7eb 185 PIRSF PIRSF005900 1 162 7.6E-53 T 06-07-2017 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CAK77_RS19485 b65182dba07759993431b089b6cba7eb 185 Pfam PF00210 Ferritin-like domain 19 158 7.2E-26 T 06-07-2017 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 CAK77_RS19485 b65182dba07759993431b089b6cba7eb 185 ProSitePatterns PS00818 Dps protein family signature 1. 39 55 - T 06-07-2017 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 CAK77_RS19485 b65182dba07759993431b089b6cba7eb 185 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 134 152 2.4E-11 T 06-07-2017 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CAK77_RS19485 b65182dba07759993431b089b6cba7eb 185 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 63 79 2.4E-11 T 06-07-2017 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CAK77_RS19485 b65182dba07759993431b089b6cba7eb 185 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 39 55 2.4E-11 T 06-07-2017 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CAK77_RS19485 b65182dba07759993431b089b6cba7eb 185 SUPERFAMILY SSF47240 5 157 6.41E-41 T 06-07-2017 IPR009078 Ferritin-like superfamily CAK77_RS19485 b65182dba07759993431b089b6cba7eb 185 Gene3D G3DSA:1.20.1260.10 4 158 2.6E-47 T 06-07-2017 IPR012347 Ferritin-related CAK77_RS15095 863ea08aab23c8d4d35d35d7ac306b41 483 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 360 467 2.4E-25 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CAK77_RS15095 863ea08aab23c8d4d35d35d7ac306b41 483 PIRSF PIRSF000350 6 480 5.1E-73 T 06-07-2017 CAK77_RS15095 863ea08aab23c8d4d35d35d7ac306b41 483 Gene3D G3DSA:3.50.50.60 159 346 1.2E-53 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS15095 863ea08aab23c8d4d35d35d7ac306b41 483 Gene3D G3DSA:3.50.50.60 18 158 3.1E-33 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS15095 863ea08aab23c8d4d35d35d7ac306b41 483 Gene3D G3DSA:3.30.390.30 347 475 3.1E-28 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CAK77_RS15095 863ea08aab23c8d4d35d35d7ac306b41 483 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 21 40 1.1E-31 T 06-07-2017 CAK77_RS15095 863ea08aab23c8d4d35d35d7ac306b41 483 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 153 171 1.1E-31 T 06-07-2017 CAK77_RS15095 863ea08aab23c8d4d35d35d7ac306b41 483 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 276 292 1.1E-31 T 06-07-2017 CAK77_RS15095 863ea08aab23c8d4d35d35d7ac306b41 483 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 305 327 1.1E-31 T 06-07-2017 CAK77_RS15095 863ea08aab23c8d4d35d35d7ac306b41 483 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 192 210 1.1E-31 T 06-07-2017 CAK77_RS15095 863ea08aab23c8d4d35d35d7ac306b41 483 SUPERFAMILY SSF51905 12 350 5.18E-55 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS15095 863ea08aab23c8d4d35d35d7ac306b41 483 SUPERFAMILY SSF55424 358 478 1.01E-29 T 06-07-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CAK77_RS15095 863ea08aab23c8d4d35d35d7ac306b41 483 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 19 340 6.8E-59 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS15095 863ea08aab23c8d4d35d35d7ac306b41 483 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 53 68 3.1E-57 T 06-07-2017 CAK77_RS15095 863ea08aab23c8d4d35d35d7ac306b41 483 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 277 291 3.1E-57 T 06-07-2017 CAK77_RS15095 863ea08aab23c8d4d35d35d7ac306b41 483 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 156 165 3.1E-57 T 06-07-2017 CAK77_RS15095 863ea08aab23c8d4d35d35d7ac306b41 483 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 20 42 3.1E-57 T 06-07-2017 CAK77_RS15095 863ea08aab23c8d4d35d35d7ac306b41 483 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 420 435 3.1E-57 T 06-07-2017 CAK77_RS15095 863ea08aab23c8d4d35d35d7ac306b41 483 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 192 217 3.1E-57 T 06-07-2017 CAK77_RS15095 863ea08aab23c8d4d35d35d7ac306b41 483 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 355 376 3.1E-57 T 06-07-2017 CAK77_RS15095 863ea08aab23c8d4d35d35d7ac306b41 483 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 320 327 3.1E-57 T 06-07-2017 CAK77_RS15095 863ea08aab23c8d4d35d35d7ac306b41 483 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 442 462 3.1E-57 T 06-07-2017 CAK77_RS02505 e5658f15a3fd32a73538cad3cf3ecb46 210 Gene3D G3DSA:1.10.357.10 17 196 6.8E-35 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS02505 e5658f15a3fd32a73538cad3cf3ecb46 210 SUPERFAMILY SSF46689 12 91 1.54E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS02505 e5658f15a3fd32a73538cad3cf3ecb46 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 35 2.0E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS02505 e5658f15a3fd32a73538cad3cf3ecb46 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 66 2.0E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS02505 e5658f15a3fd32a73538cad3cf3ecb46 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 63 5.2E-16 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS23830 27e21201e9fb4a6f6aa40a6da6b67249 496 Pfam PF00823 PPE family 8 162 9.8E-60 T 06-07-2017 IPR000030 PPE family CAK77_RS23830 27e21201e9fb4a6f6aa40a6da6b67249 496 SUPERFAMILY SSF140459 5 177 9.94E-61 T 06-07-2017 CAK77_RS05765 252a623f260c3b24aa34f1cb88c384f9 296 Pfam PF03239 Iron permease FTR1 family 18 267 4.4E-39 T 06-07-2017 IPR004923 Iron permease FTR1/Fip1/EfeU GO:0005381|GO:0006827|GO:0016020|GO:0033573 CAK77_RS18525 92bfa7c65a920689aa63b7c91af0f9be 507 SUPERFAMILY SSF54631 107 217 1.64E-28 T 06-07-2017 CAK77_RS18525 92bfa7c65a920689aa63b7c91af0f9be 507 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 22 475 1.0E-183 T 06-07-2017 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CAK77_RS18525 92bfa7c65a920689aa63b7c91af0f9be 507 PIRSF PIRSF000130 13 507 4.5E-202 T 06-07-2017 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CAK77_RS18525 92bfa7c65a920689aa63b7c91af0f9be 507 SMART SM01240 21 493 0.0 T 06-07-2017 CAK77_RS18525 92bfa7c65a920689aa63b7c91af0f9be 507 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 22 506 84.181 T 06-07-2017 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CAK77_RS18525 92bfa7c65a920689aa63b7c91af0f9be 507 Pfam PF00571 CBS domain 163 216 2.8E-8 T 06-07-2017 IPR000644 CBS domain CAK77_RS18525 92bfa7c65a920689aa63b7c91af0f9be 507 Pfam PF00571 CBS domain 107 153 1.6E-6 T 06-07-2017 IPR000644 CBS domain CAK77_RS18525 92bfa7c65a920689aa63b7c91af0f9be 507 SMART SM00116 171 219 6.9E-7 T 06-07-2017 IPR000644 CBS domain CAK77_RS18525 92bfa7c65a920689aa63b7c91af0f9be 507 SMART SM00116 110 158 4.1E-6 T 06-07-2017 IPR000644 CBS domain CAK77_RS18525 92bfa7c65a920689aa63b7c91af0f9be 507 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 309 321 - T 06-07-2017 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 CAK77_RS18525 92bfa7c65a920689aa63b7c91af0f9be 507 SUPERFAMILY SSF51412 16 104 2.22E-113 T 06-07-2017 CAK77_RS18525 92bfa7c65a920689aa63b7c91af0f9be 507 SUPERFAMILY SSF51412 230 497 2.22E-113 T 06-07-2017 CAK77_RS18525 92bfa7c65a920689aa63b7c91af0f9be 507 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 22 493 8.3E-155 T 06-07-2017 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 CAK77_RS18525 92bfa7c65a920689aa63b7c91af0f9be 507 Gene3D G3DSA:3.20.20.70 19 504 2.8E-190 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK77_RS17020 bc4ba9f80b7dabbeb74041aac871b268 80 Pfam PF00462 Glutaredoxin 3 61 2.2E-15 T 06-07-2017 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 CAK77_RS17020 bc4ba9f80b7dabbeb74041aac871b268 80 TIGRFAM TIGR02194 GlrX_NrdH: glutaredoxin-like protein NrdH 3 73 5.1E-35 T 06-07-2017 IPR011909 Glutaredoxin-like protein NrdH GO:0045454 CAK77_RS17020 bc4ba9f80b7dabbeb74041aac871b268 80 Gene3D G3DSA:3.40.30.10 1 75 5.6E-30 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK77_RS17020 bc4ba9f80b7dabbeb74041aac871b268 80 SUPERFAMILY SSF52833 1 73 1.35E-19 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK77_RS01545 33db1682d568d7212003f81a8a330e8f 161 Pfam PF01844 HNH endonuclease 90 121 2.3E-5 T 06-07-2017 IPR002711 HNH endonuclease GO:0003676|GO:0004519 CAK77_RS01545 33db1682d568d7212003f81a8a330e8f 161 Pfam PF02720 Domain of unknown function (DUF222) 2 82 1.5E-23 T 06-07-2017 IPR003870 Domain of unknown function DUF222 CAK77_RS01545 33db1682d568d7212003f81a8a330e8f 161 SMART SM00507 73 125 2.9E-8 T 06-07-2017 IPR003615 HNH nuclease CAK77_RS09340 7e5bf8add4f7f66928d4fef85eca6f7c 429 PRINTS PR00344 Bacterial sensor protein C-terminal signature 390 408 7.7E-8 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK77_RS09340 7e5bf8add4f7f66928d4fef85eca6f7c 429 PRINTS PR00344 Bacterial sensor protein C-terminal signature 358 372 7.7E-8 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK77_RS09340 7e5bf8add4f7f66928d4fef85eca6f7c 429 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 325 426 2.2E-17 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS09340 7e5bf8add4f7f66928d4fef85eca6f7c 429 Gene3D G3DSA:3.30.565.10 284 426 7.0E-28 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS09340 7e5bf8add4f7f66928d4fef85eca6f7c 429 SMART SM00388 213 279 1.1E-9 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK77_RS09340 7e5bf8add4f7f66928d4fef85eca6f7c 429 SUPERFAMILY SSF55874 282 426 1.57E-29 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS09340 7e5bf8add4f7f66928d4fef85eca6f7c 429 Pfam PF00512 His Kinase A (phospho-acceptor) domain 215 276 1.5E-8 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK77_RS09340 7e5bf8add4f7f66928d4fef85eca6f7c 429 Pfam PF00672 HAMP domain 135 200 5.1E-9 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAK77_RS09340 7e5bf8add4f7f66928d4fef85eca6f7c 429 SUPERFAMILY SSF47384 202 274 3.53E-10 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK77_RS09340 7e5bf8add4f7f66928d4fef85eca6f7c 429 SMART SM00387 322 429 6.0E-19 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS09340 7e5bf8add4f7f66928d4fef85eca6f7c 429 Gene3D G3DSA:1.10.287.130 209 274 1.1E-8 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK77_RS14070 2803a7051134ddbc840bc1f908282174 788 Gene3D G3DSA:3.30.460.10 234 381 1.3E-46 T 06-07-2017 CAK77_RS14070 2803a7051134ddbc840bc1f908282174 788 Pfam PF13291 ACT domain 707 783 5.2E-16 T 06-07-2017 IPR002912 ACT domain GO:0008152|GO:0016597 CAK77_RS14070 2803a7051134ddbc840bc1f908282174 788 SMART SM00954 291 401 5.2E-61 T 06-07-2017 IPR007685 RelA/SpoT GO:0015969 CAK77_RS14070 2803a7051134ddbc840bc1f908282174 788 Pfam PF13328 HD domain 84 231 1.6E-46 T 06-07-2017 IPR003607 HD/PDEase domain CAK77_RS14070 2803a7051134ddbc840bc1f908282174 788 SUPERFAMILY SSF81271 437 509 8.34E-22 T 06-07-2017 IPR012676 TGS-like KEGG: 00970+6.1.1.3 CAK77_RS14070 2803a7051134ddbc840bc1f908282174 788 SUPERFAMILY SSF55021 707 786 1.72E-13 T 06-07-2017 CAK77_RS14070 2803a7051134ddbc840bc1f908282174 788 Gene3D G3DSA:3.10.20.30 449 511 3.5E-25 T 06-07-2017 IPR012675 Beta-grasp domain CAK77_RS14070 2803a7051134ddbc840bc1f908282174 788 SUPERFAMILY SSF81301 236 454 6.87E-60 T 06-07-2017 CAK77_RS14070 2803a7051134ddbc840bc1f908282174 788 SUPERFAMILY SSF109604 60 247 9.52E-70 T 06-07-2017 CAK77_RS14070 2803a7051134ddbc840bc1f908282174 788 Pfam PF04607 Region found in RelA / SpoT proteins 291 400 5.0E-37 T 06-07-2017 IPR007685 RelA/SpoT GO:0015969 CAK77_RS14070 2803a7051134ddbc840bc1f908282174 788 Gene3D G3DSA:3.30.70.260 709 781 2.5E-12 T 06-07-2017 CAK77_RS14070 2803a7051134ddbc840bc1f908282174 788 SMART SM00471 99 209 1.7E-12 T 06-07-2017 IPR003607 HD/PDEase domain CAK77_RS14070 2803a7051134ddbc840bc1f908282174 788 Pfam PF02824 TGS domain 450 509 4.2E-23 T 06-07-2017 IPR004095 TGS KEGG: 00970+6.1.1.3 CAK77_RS14070 2803a7051134ddbc840bc1f908282174 788 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 84 783 8.4E-277 T 06-07-2017 IPR004811 RelA/SpoT family GO:0015969 CAK77_RS23595 01e25219b5ab221ee7409735c9373dbe 416 SUPERFAMILY SSF53187 311 413 1.23E-73 T 06-07-2017 CAK77_RS23595 01e25219b5ab221ee7409735c9373dbe 416 SUPERFAMILY SSF53187 10 208 1.23E-73 T 06-07-2017 CAK77_RS23595 01e25219b5ab221ee7409735c9373dbe 416 Gene3D G3DSA:3.40.630.10 308 413 1.8E-86 T 06-07-2017 CAK77_RS23595 01e25219b5ab221ee7409735c9373dbe 416 Gene3D G3DSA:3.40.630.10 14 189 1.8E-86 T 06-07-2017 CAK77_RS23595 01e25219b5ab221ee7409735c9373dbe 416 PIRSF PIRSF005962 7 416 4.0E-100 T 06-07-2017 IPR017439 Amidohydrolase GO:0016787 CAK77_RS23595 01e25219b5ab221ee7409735c9373dbe 416 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 18 365 1.3E-85 T 06-07-2017 IPR017439 Amidohydrolase GO:0016787 CAK77_RS23595 01e25219b5ab221ee7409735c9373dbe 416 Pfam PF01546 Peptidase family M20/M25/M40 74 362 1.2E-25 T 06-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CAK77_RS23595 01e25219b5ab221ee7409735c9373dbe 416 SUPERFAMILY SSF55031 195 297 3.14E-26 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAK77_RS23595 01e25219b5ab221ee7409735c9373dbe 416 Gene3D G3DSA:3.30.70.360 192 302 4.6E-34 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAK77_RS23595 01e25219b5ab221ee7409735c9373dbe 416 Pfam PF07687 Peptidase dimerisation domain 196 290 1.0E-10 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAK77_RS13595 6c5d453386ec9eacb7780ee48e7db59a 325 Pfam PF14527 WhiA LAGLIDADG-like domain 125 216 3.5E-25 T 06-07-2017 CAK77_RS13595 6c5d453386ec9eacb7780ee48e7db59a 325 Hamap MF_01420 Putative sporulation transcription regulator WhiA [whiA]. 1 304 28.898 T 06-07-2017 IPR003802 Sporulation regulator WhiA GO:0043937 CAK77_RS13595 6c5d453386ec9eacb7780ee48e7db59a 325 Pfam PF02650 WhiA C-terminal HTH domain 219 301 4.3E-19 T 06-07-2017 IPR023054 Sporulation regulator WhiA, C-terminal CAK77_RS13595 6c5d453386ec9eacb7780ee48e7db59a 325 TIGRFAM TIGR00647 DNA_bind_WhiA: DNA-binding protein WhiA 2 302 5.5E-109 T 06-07-2017 CAK77_RS13595 6c5d453386ec9eacb7780ee48e7db59a 325 Pfam PF10298 WhiA N-terminal LAGLIDADG-like domain 19 102 8.2E-24 T 06-07-2017 IPR018478 Sporulation transcription regulator WhiA, N-terminal domain CAK77_RS04030 ddbecfc0de7f75c9635edbb0513b6d19 225 SUPERFAMILY SSF109755 2 214 8.06E-54 T 06-07-2017 CAK77_RS04030 ddbecfc0de7f75c9635edbb0513b6d19 225 PIRSF PIRSF003107 1 216 5.3E-50 T 06-07-2017 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 CAK77_RS04030 ddbecfc0de7f75c9635edbb0513b6d19 225 Gene3D G3DSA:1.20.58.220 1 106 2.9E-23 T 06-07-2017 CAK77_RS04030 ddbecfc0de7f75c9635edbb0513b6d19 225 Gene3D G3DSA:1.20.58.220 111 210 3.3E-18 T 06-07-2017 CAK77_RS04030 ddbecfc0de7f75c9635edbb0513b6d19 225 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 4 211 9.8E-59 T 06-07-2017 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 CAK77_RS04030 ddbecfc0de7f75c9635edbb0513b6d19 225 Pfam PF01895 PhoU domain 17 103 4.8E-13 T 06-07-2017 IPR026022 PhoU domain CAK77_RS04030 ddbecfc0de7f75c9635edbb0513b6d19 225 Pfam PF01895 PhoU domain 122 204 4.2E-11 T 06-07-2017 IPR026022 PhoU domain CAK77_RS08335 5d26964c093bc457f366b4c1f751735b 86 SUPERFAMILY SSF46992 3 86 1.57E-29 T 06-07-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS08335 5d26964c093bc457f366b4c1f751735b 86 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 17.048 T 06-07-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS08335 5d26964c093bc457f366b4c1f751735b 86 Gene3D G3DSA:1.20.58.110 2 86 2.1E-30 T 06-07-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS08335 5d26964c093bc457f366b4c1f751735b 86 TIGRFAM TIGR00029 S20: ribosomal protein bS20 2 86 1.2E-25 T 06-07-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS08335 5d26964c093bc457f366b4c1f751735b 86 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 12 68 3.0E-18 T 06-07-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS08335 5d26964c093bc457f366b4c1f751735b 86 Pfam PF01649 Ribosomal protein S20 2 84 1.2E-29 T 06-07-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS18150 814d24f2edab784c8e5aac11d2cf12cc 151 Gene3D G3DSA:2.30.110.10 4 101 4.4E-13 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS18150 814d24f2edab784c8e5aac11d2cf12cc 151 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 18 84 2.1E-5 T 06-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAK77_RS18150 814d24f2edab784c8e5aac11d2cf12cc 151 SUPERFAMILY SSF50475 4 101 2.43E-13 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS01660 9669aebf03b2ece252211863660863f6 393 Gene3D G3DSA:2.40.110.10 128 228 5.3E-26 T 06-07-2017 CAK77_RS01660 9669aebf03b2ece252211863660863f6 393 SUPERFAMILY SSF47203 237 391 1.32E-51 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS01660 9669aebf03b2ece252211863660863f6 393 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 129 226 4.6E-16 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAK77_RS01660 9669aebf03b2ece252211863660863f6 393 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 124 3.0E-14 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS01660 9669aebf03b2ece252211863660863f6 393 Gene3D G3DSA:1.20.140.10 229 392 3.6E-53 T 06-07-2017 CAK77_RS01660 9669aebf03b2ece252211863660863f6 393 SUPERFAMILY SSF56645 2 250 1.06E-54 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK77_RS01660 9669aebf03b2ece252211863660863f6 393 Gene3D G3DSA:1.10.540.10 1 125 1.1E-21 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS01660 9669aebf03b2ece252211863660863f6 393 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 242 388 3.3E-39 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS23145 dc7130245c93a403f786d30a74be9817 300 Pfam PF00682 HMGL-like 7 279 4.3E-37 T 06-07-2017 IPR000891 Pyruvate carboxyltransferase GO:0003824 CAK77_RS23145 dc7130245c93a403f786d30a74be9817 300 Gene3D G3DSA:3.20.20.70 5 289 4.5E-62 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK77_RS23145 dc7130245c93a403f786d30a74be9817 300 SUPERFAMILY SSF51569 2 296 2.34E-59 T 06-07-2017 CAK77_RS05180 f521de1af973adf9494b8370aed22ae0 164 Pfam PF01047 MarR family 41 107 1.5E-11 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK77_RS05180 f521de1af973adf9494b8370aed22ae0 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 103 119 1.3E-6 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK77_RS05180 f521de1af973adf9494b8370aed22ae0 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 67 83 1.3E-6 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK77_RS05180 f521de1af973adf9494b8370aed22ae0 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 84 99 1.3E-6 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK77_RS05180 f521de1af973adf9494b8370aed22ae0 164 SUPERFAMILY SSF46785 7 153 1.13E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS05180 f521de1af973adf9494b8370aed22ae0 164 SMART SM00347 34 143 3.1E-21 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK77_RS05180 f521de1af973adf9494b8370aed22ae0 164 Gene3D G3DSA:1.10.10.10 7 153 1.4E-38 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS10455 54fff09d1f3094a1f334ec413c784981 1125 SUPERFAMILY SSF50692 609 774 4.75E-21 T 06-07-2017 IPR009010 Aspartate decarboxylase-like domain CAK77_RS10455 54fff09d1f3094a1f334ec413c784981 1125 Pfam PF00970 Oxidoreductase FAD-binding domain 790 883 5.5E-8 T 06-07-2017 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 CAK77_RS10455 54fff09d1f3094a1f334ec413c784981 1125 Gene3D G3DSA:3.40.50.740 68 151 1.1E-44 T 06-07-2017 CAK77_RS10455 54fff09d1f3094a1f334ec413c784981 1125 Gene3D G3DSA:3.40.50.740 398 613 1.1E-44 T 06-07-2017 CAK77_RS10455 54fff09d1f3094a1f334ec413c784981 1125 Gene3D G3DSA:3.10.20.30 1025 1124 1.7E-18 T 06-07-2017 IPR012675 Beta-grasp domain CAK77_RS10455 54fff09d1f3094a1f334ec413c784981 1125 SUPERFAMILY SSF53706 11 627 6.41E-121 T 06-07-2017 CAK77_RS10455 54fff09d1f3094a1f334ec413c784981 1125 Gene3D G3DSA:2.40.30.10 782 884 4.5E-21 T 06-07-2017 CAK77_RS10455 54fff09d1f3094a1f334ec413c784981 1125 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 12 63 7.2E-9 T 06-07-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS10455 54fff09d1f3094a1f334ec413c784981 1125 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 1052 1117 3.4E-9 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK77_RS10455 54fff09d1f3094a1f334ec413c784981 1125 Gene3D G3DSA:2.20.25.90 10 67 3.7E-15 T 06-07-2017 CAK77_RS10455 54fff09d1f3094a1f334ec413c784981 1125 Gene3D G3DSA:3.40.50.80 889 1024 2.6E-23 T 06-07-2017 CAK77_RS10455 54fff09d1f3094a1f334ec413c784981 1125 SMART SM00926 11 64 2.5E-12 T 06-07-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS10455 54fff09d1f3094a1f334ec413c784981 1125 Pfam PF00384 Molybdopterin oxidoreductase 67 556 2.3E-37 T 06-07-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS10455 54fff09d1f3094a1f334ec413c784981 1125 SUPERFAMILY SSF63380 782 883 2.15E-18 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CAK77_RS10455 54fff09d1f3094a1f334ec413c784981 1125 Gene3D G3DSA:3.40.228.10 326 397 1.9E-40 T 06-07-2017 CAK77_RS10455 54fff09d1f3094a1f334ec413c784981 1125 Gene3D G3DSA:3.40.228.10 160 268 1.9E-40 T 06-07-2017 CAK77_RS10455 54fff09d1f3094a1f334ec413c784981 1125 Pfam PF01568 Molydopterin dinucleotide binding domain 650 769 1.1E-16 T 06-07-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CAK77_RS10455 54fff09d1f3094a1f334ec413c784981 1125 SUPERFAMILY SSF52343 872 1025 3.27E-22 T 06-07-2017 CAK77_RS10455 54fff09d1f3094a1f334ec413c784981 1125 Gene3D G3DSA:2.40.40.20 614 776 4.2E-16 T 06-07-2017 CAK77_RS10455 54fff09d1f3094a1f334ec413c784981 1125 Pfam PF00175 Oxidoreductase NAD-binding domain 896 1004 7.2E-7 T 06-07-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CAK77_RS10455 54fff09d1f3094a1f334ec413c784981 1125 SUPERFAMILY SSF54292 1019 1125 8.13E-20 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK77_RS10455 54fff09d1f3094a1f334ec413c784981 1125 PRINTS PR00410 Phenol hydroxylase reductase family signature 895 914 6.0E-6 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 CAK77_RS10455 54fff09d1f3094a1f334ec413c784981 1125 PRINTS PR00410 Phenol hydroxylase reductase family signature 995 1003 6.0E-6 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 CAK77_RS10455 54fff09d1f3094a1f334ec413c784981 1125 PRINTS PR00410 Phenol hydroxylase reductase family signature 816 828 6.0E-6 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 CAK77_RS10215 37e3d6d60027a67bdbf1a08e74e2cbe7 445 Gene3D G3DSA:3.30.70.360 295 340 3.6E-23 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAK77_RS10215 37e3d6d60027a67bdbf1a08e74e2cbe7 445 Gene3D G3DSA:3.30.70.360 216 255 3.6E-23 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAK77_RS10215 37e3d6d60027a67bdbf1a08e74e2cbe7 445 Pfam PF01546 Peptidase family M20/M25/M40 82 444 6.7E-37 T 06-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CAK77_RS10215 37e3d6d60027a67bdbf1a08e74e2cbe7 445 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 81 90 - T 06-07-2017 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CAK77_RS10215 37e3d6d60027a67bdbf1a08e74e2cbe7 445 Pfam PF07687 Peptidase dimerisation domain 203 340 7.0E-15 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAK77_RS10215 37e3d6d60027a67bdbf1a08e74e2cbe7 445 Gene3D G3DSA:3.40.630.10 9 215 7.5E-59 T 06-07-2017 CAK77_RS10215 37e3d6d60027a67bdbf1a08e74e2cbe7 445 Gene3D G3DSA:3.40.630.10 380 443 7.5E-59 T 06-07-2017 CAK77_RS10215 37e3d6d60027a67bdbf1a08e74e2cbe7 445 SUPERFAMILY SSF53187 9 191 2.83E-56 T 06-07-2017 CAK77_RS10215 37e3d6d60027a67bdbf1a08e74e2cbe7 445 SUPERFAMILY SSF53187 355 444 2.83E-56 T 06-07-2017 CAK77_RS10215 37e3d6d60027a67bdbf1a08e74e2cbe7 445 SUPERFAMILY SSF55031 294 347 3.72E-10 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAK77_RS10215 37e3d6d60027a67bdbf1a08e74e2cbe7 445 SUPERFAMILY SSF55031 206 248 3.72E-10 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAK77_RS16850 ccd266d125a0c0a797be57dfa9960fc5 411 Gene3D G3DSA:3.30.70.260 6 82 2.2E-16 T 06-07-2017 CAK77_RS16850 ccd266d125a0c0a797be57dfa9960fc5 411 Gene3D G3DSA:3.30.70.260 112 183 4.4E-5 T 06-07-2017 CAK77_RS16850 ccd266d125a0c0a797be57dfa9960fc5 411 Gene3D G3DSA:1.10.150.210 193 243 3.6E-25 T 06-07-2017 IPR023190 Phosphoserine phosphatase, domain 2 GO:0004647|GO:0006564 KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3|Reactome: R-HSA-977347 CAK77_RS16850 ccd266d125a0c0a797be57dfa9960fc5 411 SUPERFAMILY SSF55021 7 82 5.12E-11 T 06-07-2017 CAK77_RS16850 ccd266d125a0c0a797be57dfa9960fc5 411 Gene3D G3DSA:3.40.50.1000 244 373 4.4E-47 T 06-07-2017 IPR023214 HAD-like domain CAK77_RS16850 ccd266d125a0c0a797be57dfa9960fc5 411 SUPERFAMILY SSF56784 181 391 2.23E-50 T 06-07-2017 IPR023214 HAD-like domain CAK77_RS16850 ccd266d125a0c0a797be57dfa9960fc5 411 TIGRFAM TIGR00338 serB: phosphoserine phosphatase SerB 169 386 8.3E-74 T 06-07-2017 CAK77_RS16850 ccd266d125a0c0a797be57dfa9960fc5 411 Pfam PF12710 haloacid dehalogenase-like hydrolase 184 351 3.0E-27 T 06-07-2017 CAK77_RS16850 ccd266d125a0c0a797be57dfa9960fc5 411 Pfam PF13740 ACT domain 6 81 8.8E-22 T 06-07-2017 CAK77_RS16850 ccd266d125a0c0a797be57dfa9960fc5 411 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 183 353 8.8E-29 T 06-07-2017 IPR006383 HAD-superfamily hydrolase, subfamily IB, PSPase-like GO:0008152|GO:0016791 CAK77_RS19915 cf94ead53565548e001945c5452f496c 263 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 28 240 7.0E-42 T 06-07-2017 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 CAK77_RS07025 636f4e87f0c3e97064478306d514c0f5 598 SUPERFAMILY SSF52540 91 379 9.43E-75 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS07025 636f4e87f0c3e97064478306d514c0f5 598 Gene3D G3DSA:3.40.50.300 224 391 2.0E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS07025 636f4e87f0c3e97064478306d514c0f5 598 Hamap MF_00964 ATP-dependent RNA helicase DeaD [deaD]. 18 558 43.785 T 06-07-2017 IPR028618 ATP-dependent RNA helicase DeaD GO:0000027|GO:0004004|GO:0070417 CAK77_RS07025 636f4e87f0c3e97064478306d514c0f5 598 Pfam PF03880 DbpA RNA binding domain 486 553 1.3E-20 T 06-07-2017 IPR005580 DbpA, RNA-binding domain CAK77_RS07025 636f4e87f0c3e97064478306d514c0f5 598 Pfam PF00271 Helicase conserved C-terminal domain 249 357 2.0E-28 T 06-07-2017 IPR001650 Helicase, C-terminal CAK77_RS07025 636f4e87f0c3e97064478306d514c0f5 598 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 171 179 - T 06-07-2017 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site CAK77_RS07025 636f4e87f0c3e97064478306d514c0f5 598 Pfam PF00270 DEAD/DEAH box helicase 48 213 1.5E-47 T 06-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CAK77_RS07025 636f4e87f0c3e97064478306d514c0f5 598 SMART SM00490 276 357 1.9E-32 T 06-07-2017 IPR001650 Helicase, C-terminal CAK77_RS07025 636f4e87f0c3e97064478306d514c0f5 598 SMART SM00487 42 240 5.5E-63 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain CAK77_RS07025 636f4e87f0c3e97064478306d514c0f5 598 Gene3D G3DSA:3.40.50.300 16 223 1.3E-77 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS14320 3e7ae0ac2238f5fd82ab802f29fb121f 560 Pfam PF00916 Sulfate permease family 25 390 1.9E-87 T 06-07-2017 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 CAK77_RS14320 3e7ae0ac2238f5fd82ab802f29fb121f 560 Gene3D G3DSA:3.30.750.24 450 558 1.0E-13 T 06-07-2017 IPR002645 STAS domain CAK77_RS14320 3e7ae0ac2238f5fd82ab802f29fb121f 560 SUPERFAMILY SSF52091 450 557 1.31E-11 T 06-07-2017 IPR002645 STAS domain CAK77_RS14320 3e7ae0ac2238f5fd82ab802f29fb121f 560 Pfam PF01740 STAS domain 443 553 1.7E-15 T 06-07-2017 IPR002645 STAS domain CAK77_RS14320 3e7ae0ac2238f5fd82ab802f29fb121f 560 TIGRFAM TIGR00815 sulP: sulfate permease 12 553 4.4E-123 T 06-07-2017 IPR001902 SLC26A/SulP transporter GO:0008271|GO:0008272|GO:0016020|GO:0055085 CAK77_RS03615 83e8b252d8ff4cf9192c1e71eeb0f015 225 PIRSF PIRSF001586 1 224 3.3E-78 T 06-07-2017 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CAK77_RS03615 83e8b252d8ff4cf9192c1e71eeb0f015 225 Hamap MF_00421 Phosphoribosylformylglycinamidine synthase subunit PurQ [purQ]. 3 219 39.394 T 06-07-2017 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CAK77_RS03615 83e8b252d8ff4cf9192c1e71eeb0f015 225 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 4 204 1.1E-36 T 06-07-2017 CAK77_RS03615 83e8b252d8ff4cf9192c1e71eeb0f015 225 TIGRFAM TIGR01737 FGAM_synth_I: phosphoribosylformylglycinamidine synthase I 4 219 6.2E-80 T 06-07-2017 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CAK77_RS03615 83e8b252d8ff4cf9192c1e71eeb0f015 225 SMART SM01211 2 221 3.2E-119 T 06-07-2017 CAK77_RS03615 83e8b252d8ff4cf9192c1e71eeb0f015 225 SUPERFAMILY SSF52317 3 220 2.15E-69 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAK77_RS03615 83e8b252d8ff4cf9192c1e71eeb0f015 225 Gene3D G3DSA:3.40.50.880 2 220 8.9E-38 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAK77_RS01365 3f3e31b7752cd25827f9bd6b0ce6b7b9 319 SUPERFAMILY SSF51735 13 176 5.58E-33 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS01365 3f3e31b7752cd25827f9bd6b0ce6b7b9 319 SUPERFAMILY SSF48179 182 277 4.53E-21 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAK77_RS01365 3f3e31b7752cd25827f9bd6b0ce6b7b9 319 Gene3D G3DSA:3.40.50.720 7 186 4.1E-30 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS01365 3f3e31b7752cd25827f9bd6b0ce6b7b9 319 Pfam PF02153 Prephenate dehydrogenase 36 264 6.2E-46 T 06-07-2017 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 CAK77_RS16085 5f8f8fb6628dac44011d83ed5c2dfdf4 727 SUPERFAMILY SSF50494 144 311 1.83E-8 T 06-07-2017 IPR009003 Peptidase S1, PA clan CAK77_RS16085 5f8f8fb6628dac44011d83ed5c2dfdf4 727 SUPERFAMILY SSF48537 516 592 2.22E-10 T 06-07-2017 IPR008947 Phospholipase C/P1 nuclease domain GO:0016788 CAK77_RS16085 5f8f8fb6628dac44011d83ed5c2dfdf4 727 SUPERFAMILY SSF48537 374 482 2.22E-10 T 06-07-2017 IPR008947 Phospholipase C/P1 nuclease domain GO:0016788 CAK77_RS16085 5f8f8fb6628dac44011d83ed5c2dfdf4 727 Gene3D G3DSA:1.10.575.10 375 435 9.8E-31 T 06-07-2017 IPR008947 Phospholipase C/P1 nuclease domain GO:0016788 CAK77_RS16085 5f8f8fb6628dac44011d83ed5c2dfdf4 727 Gene3D G3DSA:1.10.575.10 495 590 9.8E-31 T 06-07-2017 IPR008947 Phospholipase C/P1 nuclease domain GO:0016788 CAK77_RS09365 b9e71ad73b496a3586081f878342c23c 292 SUPERFAMILY SSF52317 53 285 3.82E-47 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAK77_RS09365 b9e71ad73b496a3586081f878342c23c 292 Pfam PF01965 DJ-1/PfpI family 79 201 8.3E-7 T 06-07-2017 IPR002818 DJ-1/PfpI CAK77_RS09365 b9e71ad73b496a3586081f878342c23c 292 Gene3D G3DSA:3.40.50.880 8 287 5.9E-71 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAK77_RS09365 b9e71ad73b496a3586081f878342c23c 292 PIRSF PIRSF037798 3 292 9.4E-151 T 06-07-2017 IPR017283 Protein deglycase HchA KEGG: 00620+4.2.1.130|MetaCyc: PWY-901 CAK77_RS16370 acae54f0ddf09ed49dd72a3f07091ee0 343 SUPERFAMILY SSF51735 14 189 2.77E-53 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS16370 acae54f0ddf09ed49dd72a3f07091ee0 343 Gene3D G3DSA:3.40.50.720 11 194 6.3E-65 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS16370 acae54f0ddf09ed49dd72a3f07091ee0 343 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 15 170 2.5E-51 T 06-07-2017 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 CAK77_RS16370 acae54f0ddf09ed49dd72a3f07091ee0 343 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 191 332 1.4E-47 T 06-07-2017 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 CAK77_RS16370 acae54f0ddf09ed49dd72a3f07091ee0 343 Gene3D G3DSA:1.10.1040.10 195 338 9.2E-52 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAK77_RS16370 acae54f0ddf09ed49dd72a3f07091ee0 343 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 13 334 36.239 T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 CAK77_RS16370 acae54f0ddf09ed49dd72a3f07091ee0 343 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 199 220 - T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 CAK77_RS16370 acae54f0ddf09ed49dd72a3f07091ee0 343 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 17 34 9.0E-47 T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 CAK77_RS16370 acae54f0ddf09ed49dd72a3f07091ee0 343 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 144 164 9.0E-47 T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 CAK77_RS16370 acae54f0ddf09ed49dd72a3f07091ee0 343 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 209 233 9.0E-47 T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 CAK77_RS16370 acae54f0ddf09ed49dd72a3f07091ee0 343 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 184 208 9.0E-47 T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 CAK77_RS16370 acae54f0ddf09ed49dd72a3f07091ee0 343 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 249 266 9.0E-47 T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 CAK77_RS16370 acae54f0ddf09ed49dd72a3f07091ee0 343 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 67 94 9.0E-47 T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 CAK77_RS16370 acae54f0ddf09ed49dd72a3f07091ee0 343 PIRSF PIRSF000114 8 343 3.6E-100 T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 CAK77_RS16370 acae54f0ddf09ed49dd72a3f07091ee0 343 SUPERFAMILY SSF48179 190 343 4.25E-49 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAK77_RS02425 8cbe9af0760cddf315ebf32ad06f0476 128 Pfam PF03965 Penicillinase repressor 9 119 9.8E-25 T 06-07-2017 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 CAK77_RS02425 8cbe9af0760cddf315ebf32ad06f0476 128 SUPERFAMILY SSF46785 7 120 3.1E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS02425 8cbe9af0760cddf315ebf32ad06f0476 128 Gene3D G3DSA:1.10.10.10 8 84 1.5E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS00165 8cbe9af0760cddf315ebf32ad06f0476 128 Pfam PF03965 Penicillinase repressor 9 119 9.8E-25 T 06-07-2017 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 CAK77_RS00165 8cbe9af0760cddf315ebf32ad06f0476 128 SUPERFAMILY SSF46785 7 120 3.1E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS00165 8cbe9af0760cddf315ebf32ad06f0476 128 Gene3D G3DSA:1.10.10.10 8 84 1.5E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS13765 3bacd6d5f5c3f44e8f5fa28dbc41de61 481 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 21 457 2.9E-83 T 06-07-2017 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 CAK77_RS09260 2dcceea6caf7cdea720a13149ebb2ceb 126 SUPERFAMILY SSF54593 5 122 7.19E-16 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK77_RS09260 2dcceea6caf7cdea720a13149ebb2ceb 126 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 116 7.4E-5 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CAK77_RS09260 2dcceea6caf7cdea720a13149ebb2ceb 126 Gene3D G3DSA:3.10.180.10 6 120 3.1E-15 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK77_RS23035 87904cc732bce027856fdfa3e34687fb 365 Pfam PF00296 Luciferase-like monooxygenase 19 311 1.1E-66 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS23035 87904cc732bce027856fdfa3e34687fb 365 SUPERFAMILY SSF51679 1 343 4.58E-77 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS23035 87904cc732bce027856fdfa3e34687fb 365 Gene3D G3DSA:3.20.20.30 1 346 2.3E-84 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS06510 5e4f3d9792db97d088d308de778b6900 402 Gene3D G3DSA:1.20.1250.20 209 384 2.3E-13 T 06-07-2017 CAK77_RS06510 5e4f3d9792db97d088d308de778b6900 402 Gene3D G3DSA:1.20.1250.20 11 191 1.0E-26 T 06-07-2017 CAK77_RS06510 5e4f3d9792db97d088d308de778b6900 402 SUPERFAMILY SSF103473 10 389 3.27E-47 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK77_RS06510 5e4f3d9792db97d088d308de778b6900 402 Pfam PF07690 Major Facilitator Superfamily 15 348 8.6E-38 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK77_RS18675 3f690332b490633614472c0190c2d0aa 288 Pfam PF07224 Chlorophyllase 33 130 9.2E-5 T 06-07-2017 IPR017395 Chlorophyllase GO:0015996|GO:0047746 KEGG: 00860+3.1.1.14|MetaCyc: PWY-5098|MetaCyc: PWY-6927|MetaCyc: PWY-7164 CAK77_RS18675 3f690332b490633614472c0190c2d0aa 288 Gene3D G3DSA:3.40.50.1820 29 211 7.7E-16 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS18675 3f690332b490633614472c0190c2d0aa 288 SUPERFAMILY SSF53474 13 213 4.17E-17 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS10005 b5cdf2e73eed044596efea29d179b822 270 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 12 227 9.1E-43 T 06-07-2017 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type CAK77_RS10005 b5cdf2e73eed044596efea29d179b822 270 Gene3D G3DSA:1.20.120.450 2 149 8.0E-9 T 06-07-2017 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase CAK77_RS10005 b5cdf2e73eed044596efea29d179b822 270 TIGRFAM TIGR03084 TIGR03084: TIGR03084 family protein 7 260 9.9E-109 T 06-07-2017 IPR017518 Conserved hypothetical protein CHP03084 CAK77_RS10005 b5cdf2e73eed044596efea29d179b822 270 SUPERFAMILY SSF109854 1 154 1.8E-28 T 06-07-2017 CAK77_RS10005 b5cdf2e73eed044596efea29d179b822 270 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 13 149 4.1E-25 T 06-07-2017 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 CAK77_RS10005 b5cdf2e73eed044596efea29d179b822 270 Pfam PF08608 Wyosine base formation 186 237 1.2E-10 T 06-07-2017 IPR013917 tRNA wybutosine-synthesis MetaCyc: PWY-7285|MetaCyc: PWY-7286 CAK77_RS16000 2df552a5fcadfdb9284525113b8a3a35 250 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 104 245 1.8E-16 T 06-07-2017 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 CAK77_RS16000 2df552a5fcadfdb9284525113b8a3a35 250 SUPERFAMILY SSF46689 30 100 2.05E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS16000 2df552a5fcadfdb9284525113b8a3a35 250 Gene3D G3DSA:1.10.357.10 29 246 9.3E-51 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS16000 2df552a5fcadfdb9284525113b8a3a35 250 Pfam PF00440 Bacterial regulatory proteins, tetR family 40 83 1.4E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS16000 2df552a5fcadfdb9284525113b8a3a35 250 SUPERFAMILY SSF48498 103 245 9.64E-22 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS01280 2c555b4e75211950af15c2590c8f287f 197 SUPERFAMILY SSF46689 8 82 8.98E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS01280 2c555b4e75211950af15c2590c8f287f 197 Gene3D G3DSA:1.10.357.10 60 195 4.5E-22 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS01280 2c555b4e75211950af15c2590c8f287f 197 Gene3D G3DSA:1.10.10.60 8 59 5.0E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS01280 2c555b4e75211950af15c2590c8f287f 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 61 3.4E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS21115 379cbe4556909874777cafbfeb4ec20d 500 Pfam PF04389 Peptidase family M28 252 472 2.6E-44 T 06-07-2017 IPR007484 Peptidase M28 CAK77_RS21115 379cbe4556909874777cafbfeb4ec20d 500 Pfam PF02225 PA domain 140 230 1.4E-14 T 06-07-2017 IPR003137 PA domain CAK77_RS21115 379cbe4556909874777cafbfeb4ec20d 500 SUPERFAMILY SSF52025 111 229 7.19E-18 T 06-07-2017 CAK77_RS21115 379cbe4556909874777cafbfeb4ec20d 500 SUPERFAMILY SSF53187 235 478 1.23E-55 T 06-07-2017 CAK77_RS21115 379cbe4556909874777cafbfeb4ec20d 500 Gene3D G3DSA:3.50.30.30 133 233 1.5E-24 T 06-07-2017 CAK77_RS21115 379cbe4556909874777cafbfeb4ec20d 500 Gene3D G3DSA:3.40.630.10 52 115 4.1E-63 T 06-07-2017 CAK77_RS21115 379cbe4556909874777cafbfeb4ec20d 500 Gene3D G3DSA:3.40.630.10 251 479 4.1E-63 T 06-07-2017 CAK77_RS05620 0ac92c930addcf709436593224f7033d 981 SUPERFAMILY SSF82866 154 357 4.32E-28 T 06-07-2017 CAK77_RS05620 0ac92c930addcf709436593224f7033d 981 SUPERFAMILY SSF82866 728 937 4.58E-31 T 06-07-2017 CAK77_RS05620 0ac92c930addcf709436593224f7033d 981 Pfam PF03176 MMPL family 52 390 1.6E-111 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 CAK77_RS05620 0ac92c930addcf709436593224f7033d 981 Pfam PF03176 MMPL family 614 946 4.0E-104 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 CAK77_RS05620 0ac92c930addcf709436593224f7033d 981 Gene3D G3DSA:1.20.1640.10 748 937 3.1E-23 T 06-07-2017 CAK77_RS05620 0ac92c930addcf709436593224f7033d 981 Gene3D G3DSA:1.20.1640.10 153 362 2.4E-27 T 06-07-2017 CAK77_RS05620 0ac92c930addcf709436593224f7033d 981 TIGRFAM TIGR00833 actII: transport protein 19 937 0.0 T 06-07-2017 IPR004707 Membrane transport protein MmpL family GO:0016021 CAK77_RS14935 5121505563d6d0fecdd7f85cd0d5c59a 286 SUPERFAMILY SSF51735 2 263 8.1E-45 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS14935 5121505563d6d0fecdd7f85cd0d5c59a 286 Pfam PF13460 NAD(P)H-binding 7 174 1.6E-15 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS14935 5121505563d6d0fecdd7f85cd0d5c59a 286 Gene3D G3DSA:3.40.50.720 1 210 3.0E-26 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS05380 6c71f63f4a20ceb545f43e94a421f46a 682 Gene3D G3DSA:3.30.1490.20 153 203 4.2E-19 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CAK77_RS05380 6c71f63f4a20ceb545f43e94a421f46a 682 Pfam PF02785 Biotin carboxylase C-terminal domain 337 455 1.7E-29 T 06-07-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAK77_RS05380 6c71f63f4a20ceb545f43e94a421f46a 682 SUPERFAMILY SSF56059 93 330 3.89E-56 T 06-07-2017 CAK77_RS05380 6c71f63f4a20ceb545f43e94a421f46a 682 SUPERFAMILY SSF51230 603 671 4.84E-19 T 06-07-2017 IPR011053 Single hybrid motif CAK77_RS05380 6c71f63f4a20ceb545f43e94a421f46a 682 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 628 645 - T 06-07-2017 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAK77_RS05380 6c71f63f4a20ceb545f43e94a421f46a 682 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 289 296 - T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CAK77_RS05380 6c71f63f4a20ceb545f43e94a421f46a 682 Gene3D G3DSA:2.40.50.100 604 671 2.0E-21 T 06-07-2017 CAK77_RS05380 6c71f63f4a20ceb545f43e94a421f46a 682 Pfam PF00364 Biotin-requiring enzyme 607 671 2.9E-15 T 06-07-2017 IPR000089 Biotin/lipoyl attachment CAK77_RS05380 6c71f63f4a20ceb545f43e94a421f46a 682 Gene3D G3DSA:3.40.50.20 12 140 8.0E-49 T 06-07-2017 IPR016185 Pre-ATP-grasp domain CAK77_RS05380 6c71f63f4a20ceb545f43e94a421f46a 682 Gene3D G3DSA:3.30.470.20 207 457 9.8E-86 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAK77_RS05380 6c71f63f4a20ceb545f43e94a421f46a 682 SMART SM00878 337 455 2.7E-43 T 06-07-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAK77_RS05380 6c71f63f4a20ceb545f43e94a421f46a 682 Pfam PF00289 Biotin carboxylase, N-terminal domain 12 120 1.6E-41 T 06-07-2017 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAK77_RS05380 6c71f63f4a20ceb545f43e94a421f46a 682 SUPERFAMILY SSF52440 10 123 7.19E-46 T 06-07-2017 IPR016185 Pre-ATP-grasp domain CAK77_RS05380 6c71f63f4a20ceb545f43e94a421f46a 682 SUPERFAMILY SSF51246 332 457 6.28E-33 T 06-07-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAK77_RS05380 6c71f63f4a20ceb545f43e94a421f46a 682 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 149 325 1.6E-60 T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CAK77_RS02965 8891fe59a619e044c90a22e4d04621ff 474 SUPERFAMILY SSF47323 324 467 7.98E-29 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK77_RS02965 8891fe59a619e044c90a22e4d04621ff 474 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 7 466 6.4E-128 T 06-07-2017 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 CAK77_RS02965 8891fe59a619e044c90a22e4d04621ff 474 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 228 249 4.3E-26 T 06-07-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CAK77_RS02965 8891fe59a619e044c90a22e4d04621ff 474 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 66 75 4.3E-26 T 06-07-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CAK77_RS02965 8891fe59a619e044c90a22e4d04621ff 474 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 197 215 4.3E-26 T 06-07-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CAK77_RS02965 8891fe59a619e044c90a22e4d04621ff 474 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 30 41 4.3E-26 T 06-07-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CAK77_RS02965 8891fe59a619e044c90a22e4d04621ff 474 SMART SM00840 346 407 2.2E-9 T 06-07-2017 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 CAK77_RS02965 8891fe59a619e044c90a22e4d04621ff 474 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 7 468 34.647 T 06-07-2017 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 CAK77_RS02965 8891fe59a619e044c90a22e4d04621ff 474 SUPERFAMILY SSF52374 8 318 6.17E-90 T 06-07-2017 CAK77_RS02965 8891fe59a619e044c90a22e4d04621ff 474 Gene3D G3DSA:3.40.50.620 24 310 2.9E-98 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS02965 8891fe59a619e044c90a22e4d04621ff 474 Pfam PF09190 DALR domain 346 398 2.3E-5 T 06-07-2017 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 CAK77_RS02965 8891fe59a619e044c90a22e4d04621ff 474 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 21 318 1.3E-123 T 06-07-2017 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 CAK77_RS02965 8891fe59a619e044c90a22e4d04621ff 474 Gene3D G3DSA:1.20.120.640 312 398 1.6E-12 T 06-07-2017 CAK77_RS13610 98f2b4158370ae45e671057b4229c5da 671 Pfam PF01541 GIY-YIG catalytic domain 18 92 1.6E-9 T 06-07-2017 IPR000305 GIY-YIG nuclease superfamily CAK77_RS13610 98f2b4158370ae45e671057b4229c5da 671 Hamap MF_00203 UvrABC system protein C [uvrC]. 4 639 30.402 T 06-07-2017 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 CAK77_RS13610 98f2b4158370ae45e671057b4229c5da 671 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 13 621 1.6E-152 T 06-07-2017 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 CAK77_RS13610 98f2b4158370ae45e671057b4229c5da 671 SUPERFAMILY SSF82771 18 101 3.4E-22 T 06-07-2017 IPR000305 GIY-YIG nuclease superfamily CAK77_RS13610 98f2b4158370ae45e671057b4229c5da 671 Gene3D G3DSA:1.10.150.20 588 640 1.0E-20 T 06-07-2017 CAK77_RS13610 98f2b4158370ae45e671057b4229c5da 671 Pfam PF02151 UvrB/uvrC motif 209 242 1.4E-9 T 06-07-2017 IPR001943 UVR domain GO:0005515 CAK77_RS13610 98f2b4158370ae45e671057b4229c5da 671 SMART SM00278 588 607 100.0 T 06-07-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CAK77_RS13610 98f2b4158370ae45e671057b4229c5da 671 SMART SM00278 620 639 1.2 T 06-07-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CAK77_RS13610 98f2b4158370ae45e671057b4229c5da 671 Gene3D G3DSA:4.10.860.10 187 247 2.1E-18 T 06-07-2017 IPR001943 UVR domain GO:0005515 CAK77_RS13610 98f2b4158370ae45e671057b4229c5da 671 Gene3D G3DSA:3.40.1440.10 17 95 9.1E-9 T 06-07-2017 IPR027299 GIY-YIG domain CAK77_RS13610 98f2b4158370ae45e671057b4229c5da 671 SUPERFAMILY SSF47781 526 639 2.32E-25 T 06-07-2017 IPR010994 RuvA domain 2-like CAK77_RS13610 98f2b4158370ae45e671057b4229c5da 671 SUPERFAMILY SSF46600 194 247 1.44E-13 T 06-07-2017 IPR001943 UVR domain GO:0005515 CAK77_RS13610 98f2b4158370ae45e671057b4229c5da 671 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 406 574 5.8E-49 T 06-07-2017 IPR001162 UvrC family homology region CAK77_RS13610 98f2b4158370ae45e671057b4229c5da 671 Pfam PF14520 Helix-hairpin-helix domain 590 640 2.0E-10 T 06-07-2017 CAK77_RS13610 98f2b4158370ae45e671057b4229c5da 671 SMART SM00465 17 99 8.9E-22 T 06-07-2017 IPR000305 GIY-YIG nuclease superfamily CAK77_RS17545 e1aca8431d4c48a8ce9022fb903470b2 453 TIGRFAM TIGR03624 TIGR03624: putative hydrolase 75 426 8.8E-120 T 06-07-2017 IPR018766 Zinicin-like metallopeptidase type 2 CAK77_RS17545 e1aca8431d4c48a8ce9022fb903470b2 453 Pfam PF10103 Zinicin-like metallopeptidase 75 423 1.6E-113 T 06-07-2017 IPR018766 Zinicin-like metallopeptidase type 2 CAK77_RS17545 e1aca8431d4c48a8ce9022fb903470b2 453 SUPERFAMILY SSF55486 74 426 2.34E-110 T 06-07-2017 CAK77_RS15860 b4e063c9448ff09ff3a7c3a93464ac4a 185 Gene3D G3DSA:1.10.132.20 66 185 1.4E-41 T 06-07-2017 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 CAK77_RS15860 b4e063c9448ff09ff3a7c3a93464ac4a 185 TIGRFAM TIGR00496 frr: ribosome recycling factor 10 185 4.4E-66 T 06-07-2017 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 CAK77_RS15860 b4e063c9448ff09ff3a7c3a93464ac4a 185 Pfam PF01765 Ribosome recycling factor 21 183 9.8E-61 T 06-07-2017 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 CAK77_RS15860 b4e063c9448ff09ff3a7c3a93464ac4a 185 SUPERFAMILY SSF55194 3 184 1.31E-68 T 06-07-2017 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 CAK77_RS15860 b4e063c9448ff09ff3a7c3a93464ac4a 185 Hamap MF_00040 Ribosome-recycling factor [frr]. 3 185 26.727 T 06-07-2017 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 CAK77_RS13070 fa244e4af32cbb4f3aa4765106424954 244 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 4 242 31.684 T 06-07-2017 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 CAK77_RS13070 fa244e4af32cbb4f3aa4765106424954 244 Gene3D G3DSA:3.20.20.70 5 242 1.0E-68 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK77_RS13070 fa244e4af32cbb4f3aa4765106424954 244 Pfam PF00977 Histidine biosynthesis protein 5 235 1.0E-59 T 06-07-2017 IPR006062 Histidine biosynthesis GO:0000105 CAK77_RS13070 fa244e4af32cbb4f3aa4765106424954 244 TIGRFAM TIGR01919 hisA-trpF: bifunctional HisA/TrpF protein 2 243 1.2E-124 T 06-07-2017 IPR010188 Bifunctional HisA/TrpF GO:0000105|GO:0000162|GO:0003949|GO:0004640|GO:0005737 KEGG: 00340+5.3.1.16 CAK77_RS13070 fa244e4af32cbb4f3aa4765106424954 244 SUPERFAMILY SSF51366 4 241 1.73E-60 T 06-07-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CAK77_RS12895 760ed465685a449317a855a129b5a74e 241 PIRSF PIRSF039137 2 241 4.5E-102 T 06-07-2017 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein GO:0015658|GO:0015803 CAK77_RS12895 760ed465685a449317a855a129b5a74e 241 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK77_RS12895 760ed465685a449317a855a129b5a74e 241 Pfam PF00005 ABC transporter 22 168 4.9E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK77_RS12895 760ed465685a449317a855a129b5a74e 241 SUPERFAMILY SSF52540 5 237 4.42E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS12895 760ed465685a449317a855a129b5a74e 241 Gene3D G3DSA:3.40.50.300 5 236 4.7E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS12895 760ed465685a449317a855a129b5a74e 241 SMART SM00382 30 217 2.3E-7 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS17280 0c038543217983c7d357eb57a23f19e6 150 Gene3D G3DSA:2.60.40.790 6 129 2.9E-26 T 06-07-2017 IPR008978 HSP20-like chaperone CAK77_RS17280 0c038543217983c7d357eb57a23f19e6 150 Pfam PF00011 Hsp20/alpha crystallin family 32 128 1.3E-21 T 06-07-2017 IPR002068 Alpha crystallin/Hsp20 domain CAK77_RS17280 0c038543217983c7d357eb57a23f19e6 150 SUPERFAMILY SSF49764 4 128 3.49E-29 T 06-07-2017 IPR008978 HSP20-like chaperone CAK77_RS08090 fd7a7e78a7292c34b3f869432e496f3b 426 Gene3D G3DSA:1.10.8.60 316 415 1.4E-35 T 06-07-2017 CAK77_RS08090 fd7a7e78a7292c34b3f869432e496f3b 426 Pfam PF07724 AAA domain (Cdc48 subfamily) 114 311 1.9E-50 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 CAK77_RS08090 fd7a7e78a7292c34b3f869432e496f3b 426 SUPERFAMILY SSF52540 59 400 4.38E-76 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS08090 fd7a7e78a7292c34b3f869432e496f3b 426 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 317 395 9.5E-17 T 06-07-2017 IPR019489 Clp ATPase, C-terminal CAK77_RS08090 fd7a7e78a7292c34b3f869432e496f3b 426 SUPERFAMILY SSF57716 11 46 1.37E-11 T 06-07-2017 CAK77_RS08090 fd7a7e78a7292c34b3f869432e496f3b 426 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 2 415 52.567 T 06-07-2017 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 CAK77_RS08090 fd7a7e78a7292c34b3f869432e496f3b 426 Pfam PF06689 ClpX C4-type zinc finger 11 48 8.9E-21 T 06-07-2017 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 CAK77_RS08090 fd7a7e78a7292c34b3f869432e496f3b 426 Gene3D G3DSA:3.40.50.300 294 311 2.0E-49 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS08090 fd7a7e78a7292c34b3f869432e496f3b 426 Gene3D G3DSA:3.40.50.300 63 255 2.0E-49 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS08090 fd7a7e78a7292c34b3f869432e496f3b 426 SMART SM01086 317 404 1.3E-31 T 06-07-2017 IPR019489 Clp ATPase, C-terminal CAK77_RS08090 fd7a7e78a7292c34b3f869432e496f3b 426 SMART SM00994 10 49 1.1E-23 T 06-07-2017 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 CAK77_RS08090 fd7a7e78a7292c34b3f869432e496f3b 426 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 9 411 7.8E-196 T 06-07-2017 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 CAK77_RS08090 fd7a7e78a7292c34b3f869432e496f3b 426 SMART SM00382 113 269 1.1E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS06565 cfbbb60fe5941ec2ddda0e9e243a71be 657 Pfam PF00679 Elongation factor G C-terminus 443 527 1.3E-23 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain CAK77_RS06565 cfbbb60fe5941ec2ddda0e9e243a71be 657 Gene3D G3DSA:3.40.50.300 25 247 1.5E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS06565 cfbbb60fe5941ec2ddda0e9e243a71be 657 SUPERFAMILY SSF54980 348 434 1.58E-7 T 06-07-2017 IPR009022 Elongation factor G, III-V domain CAK77_RS06565 cfbbb60fe5941ec2ddda0e9e243a71be 657 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 28 645 4.6E-270 T 06-07-2017 IPR006298 GTP-binding protein TypA GO:0005525 CAK77_RS06565 cfbbb60fe5941ec2ddda0e9e243a71be 657 SUPERFAMILY SSF54980 445 559 1.29E-27 T 06-07-2017 IPR009022 Elongation factor G, III-V domain CAK77_RS06565 cfbbb60fe5941ec2ddda0e9e243a71be 657 Gene3D G3DSA:2.40.30.10 248 349 1.4E-29 T 06-07-2017 CAK77_RS06565 cfbbb60fe5941ec2ddda0e9e243a71be 657 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 29 168 1.5E-22 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 CAK77_RS06565 cfbbb60fe5941ec2ddda0e9e243a71be 657 PRINTS PR00315 GTP-binding elongation factor signature 152 161 2.1E-15 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAK77_RS06565 cfbbb60fe5941ec2ddda0e9e243a71be 657 PRINTS PR00315 GTP-binding elongation factor signature 75 83 2.1E-15 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAK77_RS06565 cfbbb60fe5941ec2ddda0e9e243a71be 657 PRINTS PR00315 GTP-binding elongation factor signature 30 43 2.1E-15 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAK77_RS06565 cfbbb60fe5941ec2ddda0e9e243a71be 657 PRINTS PR00315 GTP-binding elongation factor signature 100 110 2.1E-15 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAK77_RS06565 cfbbb60fe5941ec2ddda0e9e243a71be 657 PRINTS PR00315 GTP-binding elongation factor signature 116 127 2.1E-15 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAK77_RS06565 cfbbb60fe5941ec2ddda0e9e243a71be 657 SUPERFAMILY SSF50447 223 346 5.3E-30 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain CAK77_RS06565 cfbbb60fe5941ec2ddda0e9e243a71be 657 SMART SM00838 442 530 0.002 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain CAK77_RS06565 cfbbb60fe5941ec2ddda0e9e243a71be 657 Gene3D G3DSA:3.30.70.870 350 447 3.1E-31 T 06-07-2017 CAK77_RS06565 cfbbb60fe5941ec2ddda0e9e243a71be 657 Pfam PF03144 Elongation factor Tu domain 2 262 335 1.3E-11 T 06-07-2017 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CAK77_RS06565 cfbbb60fe5941ec2ddda0e9e243a71be 657 Gene3D G3DSA:3.30.70.240 448 527 2.6E-31 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain CAK77_RS06565 cfbbb60fe5941ec2ddda0e9e243a71be 657 Gene3D G3DSA:2.40.50.250 529 623 1.1E-34 T 06-07-2017 CAK77_RS06565 cfbbb60fe5941ec2ddda0e9e243a71be 657 SUPERFAMILY SSF52540 20 181 2.37E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS06565 cfbbb60fe5941ec2ddda0e9e243a71be 657 Pfam PF00009 Elongation factor Tu GTP binding domain 27 238 1.6E-50 T 06-07-2017 CAK77_RS14570 ebf8bce3315d874c1fc62ff43eae6f3b 151 SUPERFAMILY SSF82607 9 89 3.66E-7 T 06-07-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family CAK77_RS14570 ebf8bce3315d874c1fc62ff43eae6f3b 151 Pfam PF02575 YbaB/EbfC DNA-binding family 12 89 1.9E-7 T 06-07-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family CAK77_RS14570 ebf8bce3315d874c1fc62ff43eae6f3b 151 Gene3D G3DSA:3.30.1310.10 14 81 2.9E-6 T 06-07-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family CAK77_RS11375 95044e499d3c8df770af77530048138d 406 SUPERFAMILY SSF56266 21 402 3.66E-122 T 06-07-2017 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CAK77_RS11375 95044e499d3c8df770af77530048138d 406 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 39 404 6.0E-147 T 06-07-2017 CAK77_RS11375 95044e499d3c8df770af77530048138d 406 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 406 132.221 T 06-07-2017 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CAK77_RS11375 95044e499d3c8df770af77530048138d 406 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 16 405 5.5E-111 T 06-07-2017 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CAK77_RS11375 95044e499d3c8df770af77530048138d 406 Gene3D G3DSA:3.60.70.12 16 282 1.4E-93 T 06-07-2017 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CAK77_RS11375 95044e499d3c8df770af77530048138d 406 Pfam PF01960 ArgJ family 25 406 2.4E-129 T 06-07-2017 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CAK77_RS08085 b8968782b2e4d1cb1efaf7d63e6671bd 217 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 104 115 - T 06-07-2017 IPR018215 ClpP, Ser active site CAK77_RS08085 b8968782b2e4d1cb1efaf7d63e6671bd 217 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 17 209 38.17 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CAK77_RS08085 b8968782b2e4d1cb1efaf7d63e6671bd 217 Pfam PF00574 Clp protease 32 208 1.8E-72 T 06-07-2017 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA CAK77_RS08085 b8968782b2e4d1cb1efaf7d63e6671bd 217 Gene3D G3DSA:3.90.226.10 33 210 7.6E-72 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS08085 b8968782b2e4d1cb1efaf7d63e6671bd 217 PRINTS PR00127 Clp protease catalytic subunit P signature 125 144 3.1E-40 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CAK77_RS08085 b8968782b2e4d1cb1efaf7d63e6671bd 217 PRINTS PR00127 Clp protease catalytic subunit P signature 104 121 3.1E-40 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CAK77_RS08085 b8968782b2e4d1cb1efaf7d63e6671bd 217 PRINTS PR00127 Clp protease catalytic subunit P signature 73 93 3.1E-40 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CAK77_RS08085 b8968782b2e4d1cb1efaf7d63e6671bd 217 PRINTS PR00127 Clp protease catalytic subunit P signature 33 48 3.1E-40 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CAK77_RS08085 b8968782b2e4d1cb1efaf7d63e6671bd 217 PRINTS PR00127 Clp protease catalytic subunit P signature 184 203 3.1E-40 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CAK77_RS08085 b8968782b2e4d1cb1efaf7d63e6671bd 217 SUPERFAMILY SSF52096 26 210 4.62E-61 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS08085 b8968782b2e4d1cb1efaf7d63e6671bd 217 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 126 139 - T 06-07-2017 IPR033135 ClpP, histidine active site CAK77_RS04345 b46ec66b69193d49ba771cd8fda902a2 489 Gene3D G3DSA:3.50.50.60 263 303 3.8E-48 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS04345 b46ec66b69193d49ba771cd8fda902a2 489 Gene3D G3DSA:3.50.50.60 3 155 3.8E-48 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS04345 b46ec66b69193d49ba771cd8fda902a2 489 Pfam PF01494 FAD binding domain 5 330 8.2E-82 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 CAK77_RS04345 b46ec66b69193d49ba771cd8fda902a2 489 SUPERFAMILY SSF51905 6 165 1.49E-59 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS04345 b46ec66b69193d49ba771cd8fda902a2 489 SUPERFAMILY SSF51905 252 341 1.49E-59 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS04345 b46ec66b69193d49ba771cd8fda902a2 489 Gene3D G3DSA:3.30.9.10 156 258 2.2E-8 T 06-07-2017 CAK77_RS04345 b46ec66b69193d49ba771cd8fda902a2 489 Gene3D G3DSA:3.30.9.10 313 329 2.2E-8 T 06-07-2017 CAK77_RS04345 b46ec66b69193d49ba771cd8fda902a2 489 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 298 316 9.2E-46 T 06-07-2017 CAK77_RS04345 b46ec66b69193d49ba771cd8fda902a2 489 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 265 280 9.2E-46 T 06-07-2017 CAK77_RS04345 b46ec66b69193d49ba771cd8fda902a2 489 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 280 296 9.2E-46 T 06-07-2017 CAK77_RS04345 b46ec66b69193d49ba771cd8fda902a2 489 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 316 332 9.2E-46 T 06-07-2017 CAK77_RS04345 b46ec66b69193d49ba771cd8fda902a2 489 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 144 159 9.2E-46 T 06-07-2017 CAK77_RS04345 b46ec66b69193d49ba771cd8fda902a2 489 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 9.2E-46 T 06-07-2017 CAK77_RS22780 6b9e8a9ed1ab8b26a3ab8a06ad93dc8a 481 PIRSF PIRSF000204 5 480 1.3E-186 T 06-07-2017 IPR012136 NADP transhydrogenase, beta subunit GO:0008750|GO:0016021|GO:0050661|GO:0055114 KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 CAK77_RS22780 6b9e8a9ed1ab8b26a3ab8a06ad93dc8a 481 SUPERFAMILY SSF52467 305 479 2.75E-71 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAK77_RS22780 6b9e8a9ed1ab8b26a3ab8a06ad93dc8a 481 Pfam PF02233 NAD(P) transhydrogenase beta subunit 11 476 1.5E-172 T 06-07-2017 IPR012136 NADP transhydrogenase, beta subunit GO:0008750|GO:0016021|GO:0050661|GO:0055114 KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 CAK77_RS22780 6b9e8a9ed1ab8b26a3ab8a06ad93dc8a 481 Gene3D G3DSA:3.40.50.1220 304 479 1.6E-85 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAK77_RS08290 89e7fd8e03f2c2ad2e5bcbc64e8c5db0 278 Pfam PF02645 Uncharacterised protein, DegV family COG1307 3 276 1.5E-71 T 06-07-2017 IPR003797 DegV CAK77_RS08290 89e7fd8e03f2c2ad2e5bcbc64e8c5db0 278 Gene3D G3DSA:3.40.50.10170 1 145 1.3E-39 T 06-07-2017 CAK77_RS08290 89e7fd8e03f2c2ad2e5bcbc64e8c5db0 278 Gene3D G3DSA:3.30.1180.10 150 274 1.0E-35 T 06-07-2017 CAK77_RS08290 89e7fd8e03f2c2ad2e5bcbc64e8c5db0 278 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 4 273 1.1E-74 T 06-07-2017 IPR003797 DegV CAK77_RS08290 89e7fd8e03f2c2ad2e5bcbc64e8c5db0 278 SUPERFAMILY SSF82549 1 275 2.88E-67 T 06-07-2017 CAK77_RS18390 7c2dcfe5b51ec069bac3f7b974ece283 281 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 6 120 8.1E-33 T 06-07-2017 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CAK77_RS18390 7c2dcfe5b51ec069bac3f7b974ece283 281 Hamap MF_01576 Bifunctional protein FolD [folD]. 3 281 34.749 T 06-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CAK77_RS18390 7c2dcfe5b51ec069bac3f7b974ece283 281 Gene3D G3DSA:3.40.50.720 139 263 3.5E-45 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS18390 7c2dcfe5b51ec069bac3f7b974ece283 281 Gene3D G3DSA:3.40.192.10 7 138 6.4E-41 T 06-07-2017 CAK77_RS18390 7c2dcfe5b51ec069bac3f7b974ece283 281 SUPERFAMILY SSF51735 122 279 5.07E-42 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS18390 7c2dcfe5b51ec069bac3f7b974ece283 281 SUPERFAMILY SSF53223 2 121 5.56E-34 T 06-07-2017 CAK77_RS18390 7c2dcfe5b51ec069bac3f7b974ece283 281 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 123 280 5.5E-62 T 06-07-2017 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CAK77_RS18390 7c2dcfe5b51ec069bac3f7b974ece283 281 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 154 174 4.7E-61 T 06-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CAK77_RS18390 7c2dcfe5b51ec069bac3f7b974ece283 281 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 33 55 4.7E-61 T 06-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CAK77_RS18390 7c2dcfe5b51ec069bac3f7b974ece283 281 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 255 273 4.7E-61 T 06-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CAK77_RS18390 7c2dcfe5b51ec069bac3f7b974ece283 281 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 74 101 4.7E-61 T 06-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CAK77_RS18390 7c2dcfe5b51ec069bac3f7b974ece283 281 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 109 130 4.7E-61 T 06-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CAK77_RS18390 7c2dcfe5b51ec069bac3f7b974ece283 281 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 205 234 4.7E-61 T 06-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CAK77_RS17820 c733be9c6e83f48a35c0215240f95f09 207 SUPERFAMILY SSF53271 87 204 9.94E-13 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like CAK77_RS17820 c733be9c6e83f48a35c0215240f95f09 207 Gene3D G3DSA:3.40.50.2020 56 205 2.0E-13 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like CAK77_RS18415 99585837d6c3250c5167450d9222bc1a 197 Pfam PF13460 NAD(P)H-binding 7 186 1.5E-21 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS18415 99585837d6c3250c5167450d9222bc1a 197 SUPERFAMILY SSF51735 1 196 8.51E-33 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS18415 99585837d6c3250c5167450d9222bc1a 197 Gene3D G3DSA:3.40.50.720 1 196 2.3E-30 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS21560 ddad8e56b255ecb3033ccc41210db305 229 SUPERFAMILY SSF52833 53 225 6.27E-38 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK77_RS21560 ddad8e56b255ecb3033ccc41210db305 229 Pfam PF13462 Thioredoxin 61 225 2.1E-30 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK77_RS21560 ddad8e56b255ecb3033ccc41210db305 229 Gene3D G3DSA:3.40.30.10 55 227 1.0E-40 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK77_RS19945 67baa5aa478df41f06510cf618b1356d 691 Pfam PF01431 Peptidase family M13 480 686 2.7E-66 T 06-07-2017 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 CAK77_RS19945 67baa5aa478df41f06510cf618b1356d 691 Pfam PF05649 Peptidase family M13 51 428 2.8E-82 T 06-07-2017 IPR008753 Peptidase M13, N-terminal domain GO:0006508 CAK77_RS19945 67baa5aa478df41f06510cf618b1356d 691 SUPERFAMILY SSF55486 49 691 9.77E-186 T 06-07-2017 CAK77_RS19945 67baa5aa478df41f06510cf618b1356d 691 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 511 527 3.2E-20 T 06-07-2017 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 CAK77_RS19945 67baa5aa478df41f06510cf618b1356d 691 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 490 502 3.2E-20 T 06-07-2017 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 CAK77_RS19945 67baa5aa478df41f06510cf618b1356d 691 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 472 484 3.2E-20 T 06-07-2017 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 CAK77_RS19945 67baa5aa478df41f06510cf618b1356d 691 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 585 596 3.2E-20 T 06-07-2017 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 CAK77_RS19945 67baa5aa478df41f06510cf618b1356d 691 Gene3D G3DSA:3.40.390.10 471 691 7.0E-103 T 06-07-2017 IPR024079 Metallopeptidase, catalytic domain GO:0008237 CAK77_RS19945 67baa5aa478df41f06510cf618b1356d 691 Gene3D G3DSA:3.40.390.10 311 431 7.0E-103 T 06-07-2017 IPR024079 Metallopeptidase, catalytic domain GO:0008237 CAK77_RS22085 e2b90adc9b66b0f8c8994a037d9e358b 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 1.7E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS22085 e2b90adc9b66b0f8c8994a037d9e358b 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 139 158 1.7E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS22085 e2b90adc9b66b0f8c8994a037d9e358b 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 68 79 1.7E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS22085 e2b90adc9b66b0f8c8994a037d9e358b 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 115 131 1.7E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS22085 e2b90adc9b66b0f8c8994a037d9e358b 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 177 1.7E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS22085 e2b90adc9b66b0f8c8994a037d9e358b 231 Gene3D G3DSA:3.40.50.720 4 212 1.3E-44 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS22085 e2b90adc9b66b0f8c8994a037d9e358b 231 Pfam PF00106 short chain dehydrogenase 5 179 1.4E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS22085 e2b90adc9b66b0f8c8994a037d9e358b 231 SUPERFAMILY SSF51735 3 202 2.86E-45 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS22085 e2b90adc9b66b0f8c8994a037d9e358b 231 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 121 129 1.5E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS22085 e2b90adc9b66b0f8c8994a037d9e358b 231 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 158 1.5E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS22085 e2b90adc9b66b0f8c8994a037d9e358b 231 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 68 79 1.5E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS22085 e2b90adc9b66b0f8c8994a037d9e358b 231 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 126 154 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK77_RS03800 90dceaa02cb01af60991b5e592c59f86 275 Pfam PF00296 Luciferase-like monooxygenase 16 230 1.1E-26 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS03800 90dceaa02cb01af60991b5e592c59f86 275 SUPERFAMILY SSF51679 9 238 3.79E-40 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS03800 90dceaa02cb01af60991b5e592c59f86 275 Gene3D G3DSA:3.20.20.30 5 232 3.7E-40 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS03800 90dceaa02cb01af60991b5e592c59f86 275 TIGRFAM TIGR03856 F420_MSMEG_2906: probable F420-dependent oxidoreductase, MSMEG_2906 family 9 272 2.8E-118 T 06-07-2017 IPR022480 F420-dependent oxidoreductase, MSMEG2906 CAK77_RS03740 3e01e7d92eaeefb08b6147d2db3ead00 327 Pfam PF00107 Zinc-binding dehydrogenase 159 273 2.1E-10 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAK77_RS03740 3e01e7d92eaeefb08b6147d2db3ead00 327 SMART SM00829 9 323 1.1E-5 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAK77_RS03740 3e01e7d92eaeefb08b6147d2db3ead00 327 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 88 8.7E-6 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAK77_RS03740 3e01e7d92eaeefb08b6147d2db3ead00 327 SUPERFAMILY SSF51735 119 283 4.8E-34 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS03740 3e01e7d92eaeefb08b6147d2db3ead00 327 SUPERFAMILY SSF50129 3 146 2.13E-44 T 06-07-2017 IPR011032 GroES-like CAK77_RS03740 3e01e7d92eaeefb08b6147d2db3ead00 327 TIGRFAM TIGR02823 oxido_YhdH: putative quinone oxidoreductase, YhdH/YhfP family 4 325 2.8E-134 T 06-07-2017 IPR014188 Acrylyl-CoA reductase AcuI CAK77_RS03740 3e01e7d92eaeefb08b6147d2db3ead00 327 Gene3D G3DSA:3.40.50.720 140 292 2.0E-72 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS03740 3e01e7d92eaeefb08b6147d2db3ead00 327 Gene3D G3DSA:3.90.180.10 12 139 1.9E-10 T 06-07-2017 IPR011032 GroES-like CAK77_RS01240 ce935adf8ffd7f773a14513dd93c4a6e 627 Gene3D G3DSA:3.90.1150.10 503 618 1.7E-27 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK77_RS01240 ce935adf8ffd7f773a14513dd93c4a6e 627 SUPERFAMILY SSF53383 221 622 2.15E-122 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK77_RS01240 ce935adf8ffd7f773a14513dd93c4a6e 627 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 225 619 4.3E-164 T 06-07-2017 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 CAK77_RS01240 ce935adf8ffd7f773a14513dd93c4a6e 627 Pfam PF00266 Aminotransferase class-V 243 612 9.2E-143 T 06-07-2017 IPR000192 Aminotransferase class V domain CAK77_RS01240 ce935adf8ffd7f773a14513dd93c4a6e 627 Gene3D G3DSA:3.40.640.10 254 502 1.4E-82 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK77_RS14390 c9ce17a6cde83e6ccc2b9c82ce639e2a 334 Gene3D G3DSA:3.90.180.10 1 189 8.0E-57 T 06-07-2017 IPR011032 GroES-like CAK77_RS14390 c9ce17a6cde83e6ccc2b9c82ce639e2a 334 SUPERFAMILY SSF50129 5 173 5.02E-47 T 06-07-2017 IPR011032 GroES-like CAK77_RS14390 c9ce17a6cde83e6ccc2b9c82ce639e2a 334 SUPERFAMILY SSF51735 143 302 4.04E-24 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS14390 c9ce17a6cde83e6ccc2b9c82ce639e2a 334 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 136 7.2E-30 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAK77_RS14390 c9ce17a6cde83e6ccc2b9c82ce639e2a 334 TIGRFAM TIGR02822 adh_fam_2: zinc-binding alcohol dehydrogenase family protein 3 332 7.4E-173 T 06-07-2017 IPR014187 Alcohol dehydrogenase, zinc-binding type 2 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396 CAK77_RS14390 c9ce17a6cde83e6ccc2b9c82ce639e2a 334 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 63 77 - T 06-07-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CAK77_RS14390 c9ce17a6cde83e6ccc2b9c82ce639e2a 334 Gene3D G3DSA:3.40.50.720 190 282 8.6E-6 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS06105 5cef9dd80892045d9d7848836901fa8f 409 PRINTS PR00359 B-class P450 signature 278 289 7.1E-45 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS06105 5cef9dd80892045d9d7848836901fa8f 409 PRINTS PR00359 B-class P450 signature 345 354 7.1E-45 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS06105 5cef9dd80892045d9d7848836901fa8f 409 PRINTS PR00359 B-class P450 signature 354 365 7.1E-45 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS06105 5cef9dd80892045d9d7848836901fa8f 409 PRINTS PR00359 B-class P450 signature 90 101 7.1E-45 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS06105 5cef9dd80892045d9d7848836901fa8f 409 PRINTS PR00359 B-class P450 signature 139 155 7.1E-45 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS06105 5cef9dd80892045d9d7848836901fa8f 409 PRINTS PR00359 B-class P450 signature 156 171 7.1E-45 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS06105 5cef9dd80892045d9d7848836901fa8f 409 PRINTS PR00359 B-class P450 signature 323 338 7.1E-45 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS06105 5cef9dd80892045d9d7848836901fa8f 409 PRINTS PR00359 B-class P450 signature 295 322 7.1E-45 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS06105 5cef9dd80892045d9d7848836901fa8f 409 PRINTS PR00359 B-class P450 signature 197 219 7.1E-45 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS06105 5cef9dd80892045d9d7848836901fa8f 409 Gene3D G3DSA:1.10.630.10 13 406 3.6E-111 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS06105 5cef9dd80892045d9d7848836901fa8f 409 SUPERFAMILY SSF48264 14 406 9.3E-89 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS06105 5cef9dd80892045d9d7848836901fa8f 409 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 347 356 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CAK77_RS06105 5cef9dd80892045d9d7848836901fa8f 409 Pfam PF00067 Cytochrome P450 188 374 4.4E-24 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS04000 a67868bcfd4cdaf38ddeb74efa70c390 296 Pfam PF00583 Acetyltransferase (GNAT) family 208 284 3.9E-14 T 06-07-2017 IPR000182 GNAT domain GO:0008080 CAK77_RS04000 a67868bcfd4cdaf38ddeb74efa70c390 296 Pfam PF00583 Acetyltransferase (GNAT) family 50 125 2.4E-8 T 06-07-2017 IPR000182 GNAT domain GO:0008080 CAK77_RS04000 a67868bcfd4cdaf38ddeb74efa70c390 296 Gene3D G3DSA:3.40.630.30 15 133 2.6E-14 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS04000 a67868bcfd4cdaf38ddeb74efa70c390 296 SUPERFAMILY SSF55729 4 286 5.3E-45 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS04000 a67868bcfd4cdaf38ddeb74efa70c390 296 TIGRFAM TIGR03448 mycothiol_MshD: mycothiol synthase 4 293 6.7E-111 T 06-07-2017 IPR017813 Mycothiol acetyltransferase GO:0016747 CAK77_RS04000 a67868bcfd4cdaf38ddeb74efa70c390 296 PIRSF PIRSF021524 2 296 1.3E-98 T 06-07-2017 IPR017813 Mycothiol acetyltransferase GO:0016747 CAK77_RS04000 a67868bcfd4cdaf38ddeb74efa70c390 296 Gene3D G3DSA:3.40.630.30 157 287 3.5E-26 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS04000 a67868bcfd4cdaf38ddeb74efa70c390 296 Hamap MF_01698 Mycothiol acetyltransferase [mshD]. 2 295 34.776 T 06-07-2017 IPR017813 Mycothiol acetyltransferase GO:0016747 CAK77_RS11590 9ee0eef84724acc6bd452aa0608a72ba 215 Gene3D G3DSA:3.30.530.20 24 157 1.3E-26 T 06-07-2017 IPR023393 START-like domain CAK77_RS11590 9ee0eef84724acc6bd452aa0608a72ba 215 SUPERFAMILY SSF55961 21 157 2.63E-24 T 06-07-2017 CAK77_RS11590 9ee0eef84724acc6bd452aa0608a72ba 215 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 36 124 4.4E-9 T 06-07-2017 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CAK77_RS21155 398a6d122b1871c90568c39b95e71d09 182 SUPERFAMILY SSF55811 7 152 3.25E-26 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAK77_RS21155 398a6d122b1871c90568c39b95e71d09 182 PRINTS PR00502 NUDIX hydrolase family signature 68 83 4.7E-5 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CAK77_RS21155 398a6d122b1871c90568c39b95e71d09 182 PRINTS PR00502 NUDIX hydrolase family signature 54 68 4.7E-5 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CAK77_RS21155 398a6d122b1871c90568c39b95e71d09 182 Pfam PF00293 NUDIX domain 34 148 1.6E-17 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 CAK77_RS21155 398a6d122b1871c90568c39b95e71d09 182 Gene3D G3DSA:3.90.79.10 12 152 1.8E-29 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAK77_RS21155 398a6d122b1871c90568c39b95e71d09 182 ProSitePatterns PS00893 Nudix box signature. 59 80 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CAK77_RS04045 9f5b50efa7e420f3fda2e86306bfb40f 335 Gene3D G3DSA:1.10.620.20 4 315 3.2E-109 T 06-07-2017 IPR012348 Ribonucleotide reductase-related GO:0016491|GO:0055114 Reactome: R-HSA-499943 CAK77_RS04045 9f5b50efa7e420f3fda2e86306bfb40f 335 Pfam PF03405 Fatty acid desaturase 8 318 1.2E-82 T 06-07-2017 IPR005067 Fatty acid desaturase, type 2 GO:0006631|GO:0045300|GO:0055114 CAK77_RS04045 9f5b50efa7e420f3fda2e86306bfb40f 335 PIRSF PIRSF000346 1 330 1.3E-101 T 06-07-2017 IPR005067 Fatty acid desaturase, type 2 GO:0006631|GO:0045300|GO:0055114 CAK77_RS04045 9f5b50efa7e420f3fda2e86306bfb40f 335 SUPERFAMILY SSF47240 5 315 1.54E-85 T 06-07-2017 IPR009078 Ferritin-like superfamily CAK77_RS10955 80af619fe94d68ba58368ed6bd402a7e 550 Gene3D G3DSA:3.40.50.980 42 210 1.0E-28 T 06-07-2017 CAK77_RS10955 80af619fe94d68ba58368ed6bd402a7e 550 Gene3D G3DSA:2.30.38.10 373 448 2.7E-21 T 06-07-2017 CAK77_RS10955 80af619fe94d68ba58368ed6bd402a7e 550 Pfam PF13193 AMP-binding enzyme C-terminal domain 464 538 1.2E-11 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAK77_RS10955 80af619fe94d68ba58368ed6bd402a7e 550 Gene3D G3DSA:3.40.50.980 211 360 1.0E-31 T 06-07-2017 CAK77_RS10955 80af619fe94d68ba58368ed6bd402a7e 550 SUPERFAMILY SSF56801 28 546 9.42E-131 T 06-07-2017 CAK77_RS10955 80af619fe94d68ba58368ed6bd402a7e 550 Pfam PF00501 AMP-binding enzyme 49 453 7.4E-81 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK77_RS10955 80af619fe94d68ba58368ed6bd402a7e 550 Gene3D G3DSA:3.30.300.30 449 546 3.2E-21 T 06-07-2017 CAK77_RS14240 7836ce3deaff3bb0eb4e8836b42bcb6c 494 Pfam PF00324 Amino acid permease 28 438 8.1E-102 T 06-07-2017 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CAK77_RS14240 7836ce3deaff3bb0eb4e8836b42bcb6c 494 PIRSF PIRSF006060 6 466 5.1E-55 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CAK77_RS14240 7836ce3deaff3bb0eb4e8836b42bcb6c 494 ProSitePatterns PS00218 Amino acid permeases signature. 52 82 - T 06-07-2017 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 CAK77_RS16305 3ae0aae318385c781afc4b873d5e6c2a 480 Pfam PF00067 Cytochrome P450 34 469 4.9E-65 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS16305 3ae0aae318385c781afc4b873d5e6c2a 480 SUPERFAMILY SSF48264 32 478 2.49E-89 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS16305 3ae0aae318385c781afc4b873d5e6c2a 480 PRINTS PR00463 E-class P450 group I signature 428 451 4.5E-15 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS16305 3ae0aae318385c781afc4b873d5e6c2a 480 PRINTS PR00463 E-class P450 group I signature 61 80 4.5E-15 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS16305 3ae0aae318385c781afc4b873d5e6c2a 480 PRINTS PR00463 E-class P450 group I signature 281 298 4.5E-15 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS16305 3ae0aae318385c781afc4b873d5e6c2a 480 PRINTS PR00463 E-class P450 group I signature 418 428 4.5E-15 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS16305 3ae0aae318385c781afc4b873d5e6c2a 480 PRINTS PR00463 E-class P450 group I signature 301 327 4.5E-15 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS16305 3ae0aae318385c781afc4b873d5e6c2a 480 Gene3D G3DSA:1.10.630.10 34 479 6.0E-90 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS16305 3ae0aae318385c781afc4b873d5e6c2a 480 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 421 430 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CAK77_RS18895 b7d78c7ffef83a859e4953c3395a0821 305 SUPERFAMILY SSF53335 15 295 9.83E-79 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS18895 b7d78c7ffef83a859e4953c3395a0821 305 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 17 280 3.0E-82 T 06-07-2017 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 CAK77_RS18895 b7d78c7ffef83a859e4953c3395a0821 305 Gene3D G3DSA:3.40.50.150 13 221 5.3E-19 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS18895 b7d78c7ffef83a859e4953c3395a0821 305 Pfam PF04072 Leucine carboxyl methyltransferase 19 204 3.7E-65 T 06-07-2017 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 CAK77_RS03725 09ab6f838f501937494bfd55739d98b3 548 SUPERFAMILY SSF52540 285 529 5.1E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS03725 09ab6f838f501937494bfd55739d98b3 548 ProSitePatterns PS00211 ABC transporters family signature. 430 444 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK77_RS03725 09ab6f838f501937494bfd55739d98b3 548 SUPERFAMILY SSF52540 10 257 7.64E-69 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS03725 09ab6f838f501937494bfd55739d98b3 548 Pfam PF00005 ABC transporter 30 186 1.4E-26 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK77_RS03725 09ab6f838f501937494bfd55739d98b3 548 Pfam PF00005 ABC transporter 307 458 7.3E-28 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK77_RS03725 09ab6f838f501937494bfd55739d98b3 548 Gene3D G3DSA:3.40.50.300 283 531 2.3E-72 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS03725 09ab6f838f501937494bfd55739d98b3 548 Gene3D G3DSA:3.40.50.300 9 260 6.3E-75 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS03725 09ab6f838f501937494bfd55739d98b3 548 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK77_RS03725 09ab6f838f501937494bfd55739d98b3 548 SMART SM00382 38 236 5.5E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS03725 09ab6f838f501937494bfd55739d98b3 548 SMART SM00382 315 506 3.5E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS03725 09ab6f838f501937494bfd55739d98b3 548 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 510 541 7.1E-4 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAK77_RS03725 09ab6f838f501937494bfd55739d98b3 548 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 238 270 1.3E-5 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAK77_RS16585 58cfb3bf5bdc9beb529924c01c127a98 498 SUPERFAMILY SSF53474 5 487 1.18E-109 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS16585 58cfb3bf5bdc9beb529924c01c127a98 498 Pfam PF00135 Carboxylesterase family 7 479 9.9E-101 T 06-07-2017 IPR002018 Carboxylesterase, type B CAK77_RS16585 58cfb3bf5bdc9beb529924c01c127a98 498 ProSitePatterns PS00941 Carboxylesterases type-B signature 2. 77 87 - T 06-07-2017 IPR019819 Carboxylesterase type B, conserved site CAK77_RS16585 58cfb3bf5bdc9beb529924c01c127a98 498 Gene3D G3DSA:3.40.50.1820 4 485 5.7E-129 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS16585 58cfb3bf5bdc9beb529924c01c127a98 498 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 176 191 - T 06-07-2017 IPR019826 Carboxylesterase type B, active site CAK77_RS17475 7e116d0ee16c4d9a6cf35e4808583d9b 139 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 8 96 1.6E-12 T 06-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAK77_RS17475 7e116d0ee16c4d9a6cf35e4808583d9b 139 TIGRFAM TIGR03668 Rv0121_F420: PPOX class probable F420-dependent enzyme, Rv0121 family 6 134 2.2E-47 T 06-07-2017 IPR019967 F420-dependent enzyme, PPOX class, family Rv0121, probable CAK77_RS17475 7e116d0ee16c4d9a6cf35e4808583d9b 139 Gene3D G3DSA:2.30.110.10 5 136 9.2E-33 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS17475 7e116d0ee16c4d9a6cf35e4808583d9b 139 SUPERFAMILY SSF50475 6 133 7.32E-22 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS01620 1ef4cfd096340574de8329be849eeccd 272 SMART SM00646 130 251 4.1E-26 T 06-07-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CAK77_RS01620 1ef4cfd096340574de8329be849eeccd 272 Gene3D G3DSA:3.40.630.40 47 254 2.0E-37 T 06-07-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CAK77_RS01620 1ef4cfd096340574de8329be849eeccd 272 SUPERFAMILY SSF53187 47 254 2.42E-33 T 06-07-2017 CAK77_RS01620 1ef4cfd096340574de8329be849eeccd 272 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 49 251 1.9E-32 T 06-07-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CAK77_RS07900 2b43bde5145e9a1649b3010238b624d6 136 Gene3D G3DSA:1.10.490.10 10 135 3.0E-46 T 06-07-2017 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 CAK77_RS07900 2b43bde5145e9a1649b3010238b624d6 136 SUPERFAMILY SSF46458 11 135 4.93E-38 T 06-07-2017 IPR009050 Globin-like CAK77_RS07900 2b43bde5145e9a1649b3010238b624d6 136 Pfam PF01152 Bacterial-like globin 12 129 1.5E-40 T 06-07-2017 IPR001486 Truncated hemoglobin GO:0019825 CAK77_RS11385 7c1bbb3f77133c226a28b8b4693b8979 400 Pfam PF00202 Aminotransferase class-III 22 388 3.5E-111 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAK77_RS11385 7c1bbb3f77133c226a28b8b4693b8979 400 Gene3D G3DSA:3.90.1150.10 8 62 9.6E-37 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK77_RS11385 7c1bbb3f77133c226a28b8b4693b8979 400 Gene3D G3DSA:3.90.1150.10 303 392 9.6E-37 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK77_RS11385 7c1bbb3f77133c226a28b8b4693b8979 400 Gene3D G3DSA:3.40.640.10 64 300 1.0E-88 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK77_RS11385 7c1bbb3f77133c226a28b8b4693b8979 400 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 19 391 1.5E-147 T 06-07-2017 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 CAK77_RS11385 7c1bbb3f77133c226a28b8b4693b8979 400 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 16 392 42.817 T 06-07-2017 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 CAK77_RS11385 7c1bbb3f77133c226a28b8b4693b8979 400 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 219 256 - T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAK77_RS11385 7c1bbb3f77133c226a28b8b4693b8979 400 SUPERFAMILY SSF53383 16 392 7.53E-127 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK77_RS14785 d50c17dafe10aff1183180f04679f014 251 Pfam PF05050 Methyltransferase FkbM domain 49 225 3.5E-23 T 06-07-2017 IPR006342 Methyltransferase FkbM CAK77_RS14785 d50c17dafe10aff1183180f04679f014 251 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 46 199 2.2E-25 T 06-07-2017 IPR006342 Methyltransferase FkbM CAK77_RS14785 d50c17dafe10aff1183180f04679f014 251 Gene3D G3DSA:3.40.50.150 29 236 3.6E-34 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS14785 d50c17dafe10aff1183180f04679f014 251 SUPERFAMILY SSF53335 36 226 8.94E-35 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS02280 e59f5946c7628827f9a386ea4baf7eb4 347 SUPERFAMILY SSF52540 31 250 1.18E-25 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS02280 e59f5946c7628827f9a386ea4baf7eb4 347 Gene3D G3DSA:3.40.50.300 28 252 2.7E-32 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS02280 e59f5946c7628827f9a386ea4baf7eb4 347 Pfam PF02374 Anion-transporting ATPase 30 188 6.8E-18 T 06-07-2017 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 CAK77_RS02280 e59f5946c7628827f9a386ea4baf7eb4 347 Pfam PF02374 Anion-transporting ATPase 205 251 1.6E-5 T 06-07-2017 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 CAK77_RS22430 954b8da1a16221913c2f684f448b349f 96 SUPERFAMILY SSF140453 4 95 4.45E-13 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like CAK77_RS22430 954b8da1a16221913c2f684f448b349f 96 Gene3D G3DSA:1.10.287.1060 7 95 3.4E-13 T 06-07-2017 CAK77_RS22430 954b8da1a16221913c2f684f448b349f 96 Pfam PF06013 Proteins of 100 residues with WXG 8 87 9.5E-11 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like CAK77_RS18805 f31007fb999615133f2c53983d9158fb 350 SUPERFAMILY SSF55257 170 220 1.08E-26 T 06-07-2017 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK77_RS18805 f31007fb999615133f2c53983d9158fb 350 SUPERFAMILY SSF55257 8 48 1.08E-26 T 06-07-2017 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK77_RS18805 f31007fb999615133f2c53983d9158fb 350 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 250 321 6.0E-34 T 06-07-2017 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK77_RS18805 f31007fb999615133f2c53983d9158fb 350 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 1 311 35.273 T 06-07-2017 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK77_RS18805 f31007fb999615133f2c53983d9158fb 350 Gene3D G3DSA:1.10.150.20 248 320 1.1E-31 T 06-07-2017 CAK77_RS18805 f31007fb999615133f2c53983d9158fb 350 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 19 310 2.2E-116 T 06-07-2017 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK77_RS18805 f31007fb999615133f2c53983d9158fb 350 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 242 302 1.9E-26 T 06-07-2017 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK77_RS18805 f31007fb999615133f2c53983d9158fb 350 SUPERFAMILY SSF56553 48 169 1.44E-43 T 06-07-2017 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK77_RS18805 f31007fb999615133f2c53983d9158fb 350 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 57 149 1.2E-25 T 06-07-2017 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK77_RS18805 f31007fb999615133f2c53983d9158fb 350 Gene3D G3DSA:3.30.1360.10 7 61 3.4E-11 T 06-07-2017 CAK77_RS18805 f31007fb999615133f2c53983d9158fb 350 Gene3D G3DSA:2.170.120.12 62 168 7.2E-47 T 06-07-2017 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK77_RS18805 f31007fb999615133f2c53983d9158fb 350 SMART SM00662 18 225 4.1E-98 T 06-07-2017 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK77_RS18805 f31007fb999615133f2c53983d9158fb 350 SUPERFAMILY SSF47789 247 318 9.55E-24 T 06-07-2017 CAK77_RS18805 f31007fb999615133f2c53983d9158fb 350 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 24 218 2.2E-20 T 06-07-2017 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK77_RS08220 63f28e398e65c466369059851bc1537c 85 ProSitePatterns PS00831 Ribosomal protein L27 signature. 34 48 - T 06-07-2017 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS08220 63f28e398e65c466369059851bc1537c 85 Gene3D G3DSA:2.40.50.100 20 79 1.8E-28 T 06-07-2017 CAK77_RS08220 63f28e398e65c466369059851bc1537c 85 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 1 83 26.964 T 06-07-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS08220 63f28e398e65c466369059851bc1537c 85 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 28 70 1.0E-16 T 06-07-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS08220 63f28e398e65c466369059851bc1537c 85 TIGRFAM TIGR00062 L27: ribosomal protein bL27 1 80 5.0E-35 T 06-07-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS08220 63f28e398e65c466369059851bc1537c 85 Pfam PF01016 Ribosomal L27 protein 2 80 1.0E-35 T 06-07-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS08220 63f28e398e65c466369059851bc1537c 85 PRINTS PR00063 Ribosomal protein L27 signature 4 28 3.3E-35 T 06-07-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS08220 63f28e398e65c466369059851bc1537c 85 PRINTS PR00063 Ribosomal protein L27 signature 54 78 3.3E-35 T 06-07-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS08220 63f28e398e65c466369059851bc1537c 85 PRINTS PR00063 Ribosomal protein L27 signature 29 53 3.3E-35 T 06-07-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS08220 63f28e398e65c466369059851bc1537c 85 SUPERFAMILY SSF110324 2 80 8.02E-31 T 06-07-2017 CAK77_RS20255 006a4775db2146165cf14de0fbf7e26c 285 Gene3D G3DSA:3.40.50.720 10 249 4.7E-58 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS20255 006a4775db2146165cf14de0fbf7e26c 285 SUPERFAMILY SSF51735 6 256 4.97E-62 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS20255 006a4775db2146165cf14de0fbf7e26c 285 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK77_RS20255 006a4775db2146165cf14de0fbf7e26c 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 2.0E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS20255 006a4775db2146165cf14de0fbf7e26c 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 2.0E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS20255 006a4775db2146165cf14de0fbf7e26c 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 2.0E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS20255 006a4775db2146165cf14de0fbf7e26c 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 2.0E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS20255 006a4775db2146165cf14de0fbf7e26c 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 2.0E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS20255 006a4775db2146165cf14de0fbf7e26c 285 Pfam PF00106 short chain dehydrogenase 12 194 1.0E-45 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS20255 006a4775db2146165cf14de0fbf7e26c 285 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 1.2E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS20255 006a4775db2146165cf14de0fbf7e26c 285 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 1.2E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS20255 006a4775db2146165cf14de0fbf7e26c 285 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 1.2E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS20255 006a4775db2146165cf14de0fbf7e26c 285 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 11 192 0.0011 T 06-07-2017 CAK77_RS12700 d75d1e54afc4b0558d708da5fce99cc7 249 Gene3D G3DSA:1.10.10.10 150 247 6.6E-34 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS12700 d75d1e54afc4b0558d708da5fce99cc7 249 Pfam PF00486 Transcriptional regulatory protein, C terminal 172 245 1.1E-23 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAK77_RS12700 d75d1e54afc4b0558d708da5fce99cc7 249 SMART SM00862 171 245 2.0E-24 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAK77_RS12700 d75d1e54afc4b0558d708da5fce99cc7 249 Pfam PF00072 Response regulator receiver domain 26 135 6.1E-26 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK77_RS12700 d75d1e54afc4b0558d708da5fce99cc7 249 SMART SM00448 24 135 9.4E-40 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK77_RS12700 d75d1e54afc4b0558d708da5fce99cc7 249 SUPERFAMILY SSF52172 22 204 8.68E-41 T 06-07-2017 IPR011006 CheY-like superfamily CAK77_RS12700 d75d1e54afc4b0558d708da5fce99cc7 249 Gene3D G3DSA:3.40.50.2300 17 142 1.6E-38 T 06-07-2017 CAK77_RS24460 4f770d939acea2fb1a977e33cc32c8e5 369 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 27 116 4.2E-7 T 06-07-2017 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CAK77_RS24460 4f770d939acea2fb1a977e33cc32c8e5 369 SUPERFAMILY SSF56349 173 351 2.44E-32 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CAK77_RS24460 4f770d939acea2fb1a977e33cc32c8e5 369 SUPERFAMILY SSF47823 27 122 2.55E-5 T 06-07-2017 IPR010998 Integrase, Lambda-type, N-terminal CAK77_RS24460 4f770d939acea2fb1a977e33cc32c8e5 369 Pfam PF00589 Phage integrase family 178 342 2.2E-24 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAK77_RS24460 4f770d939acea2fb1a977e33cc32c8e5 369 Gene3D G3DSA:1.10.150.130 27 119 3.6E-12 T 06-07-2017 IPR023109 Integrase/recombinase, N-terminal CAK77_RS24460 4f770d939acea2fb1a977e33cc32c8e5 369 Gene3D G3DSA:1.10.443.10 173 347 1.4E-33 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAK77_RS22365 c4fada21b12fc4b8c8ff149ae23ade35 217 SMART SM00421 150 207 1.2E-16 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK77_RS22365 c4fada21b12fc4b8c8ff149ae23ade35 217 ProSitePatterns PS00622 LuxR-type HTH domain signature. 167 194 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK77_RS22365 c4fada21b12fc4b8c8ff149ae23ade35 217 Pfam PF00072 Response regulator receiver domain 6 110 1.4E-20 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK77_RS22365 c4fada21b12fc4b8c8ff149ae23ade35 217 Gene3D G3DSA:1.10.10.10 151 216 4.4E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS22365 c4fada21b12fc4b8c8ff149ae23ade35 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 183 1.8E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK77_RS22365 c4fada21b12fc4b8c8ff149ae23ade35 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 183 195 1.8E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK77_RS22365 c4fada21b12fc4b8c8ff149ae23ade35 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 153 167 1.8E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK77_RS22365 c4fada21b12fc4b8c8ff149ae23ade35 217 SMART SM00448 4 122 3.6E-20 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK77_RS22365 c4fada21b12fc4b8c8ff149ae23ade35 217 Gene3D G3DSA:3.40.50.2300 2 150 1.8E-29 T 06-07-2017 CAK77_RS22365 c4fada21b12fc4b8c8ff149ae23ade35 217 Pfam PF00196 Bacterial regulatory proteins, luxR family 152 197 2.7E-14 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK77_RS22365 c4fada21b12fc4b8c8ff149ae23ade35 217 SUPERFAMILY SSF52172 1 180 7.85E-26 T 06-07-2017 IPR011006 CheY-like superfamily CAK77_RS14770 2edd174def418db4b2627a395737f3c8 146 Gene3D G3DSA:3.30.530.20 10 123 9.7E-11 T 06-07-2017 IPR023393 START-like domain CAK77_RS14770 2edd174def418db4b2627a395737f3c8 146 SUPERFAMILY SSF55961 6 144 2.93E-16 T 06-07-2017 CAK77_RS05890 d90515615c1c71d4e3ad65c7d0d73ee8 440 Pfam PF13336 Acetyl-CoA hydrolase/transferase C-terminal domain 274 429 2.9E-52 T 06-07-2017 IPR026888 Acetyl-CoA hydrolase/transferase C-terminal domain CAK77_RS05890 d90515615c1c71d4e3ad65c7d0d73ee8 440 SUPERFAMILY SSF100950 190 433 1.83E-59 T 06-07-2017 CAK77_RS05890 d90515615c1c71d4e3ad65c7d0d73ee8 440 Gene3D G3DSA:3.40.810.20 191 430 1.5E-45 T 06-07-2017 CAK77_RS05890 d90515615c1c71d4e3ad65c7d0d73ee8 440 Gene3D G3DSA:3.40.1080.10 6 178 9.5E-23 T 06-07-2017 CAK77_RS05890 d90515615c1c71d4e3ad65c7d0d73ee8 440 SUPERFAMILY SSF100950 6 222 2.18E-9 T 06-07-2017 CAK77_RS10660 475b8bba52c3a1dd6c4d952bde27b33f 922 Pfam PF00271 Helicase conserved C-terminal domain 353 431 1.6E-5 T 06-07-2017 IPR001650 Helicase, C-terminal CAK77_RS10660 475b8bba52c3a1dd6c4d952bde27b33f 922 Pfam PF00270 DEAD/DEAH box helicase 22 169 1.1E-16 T 06-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CAK77_RS10660 475b8bba52c3a1dd6c4d952bde27b33f 922 SMART SM00487 16 198 7.4E-28 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain CAK77_RS10660 475b8bba52c3a1dd6c4d952bde27b33f 922 SUPERFAMILY SSF52540 30 171 1.06E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS10660 475b8bba52c3a1dd6c4d952bde27b33f 922 SUPERFAMILY SSF52540 253 309 1.06E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS10660 475b8bba52c3a1dd6c4d952bde27b33f 922 SUPERFAMILY SSF52540 351 445 1.06E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS10660 475b8bba52c3a1dd6c4d952bde27b33f 922 Pfam PF08148 DSHCT (NUC185) domain 750 917 1.4E-36 T 06-07-2017 IPR012961 ATP-dependent RNA helicase Ski2, C-terminal CAK77_RS10660 475b8bba52c3a1dd6c4d952bde27b33f 922 SMART SM01142 746 922 3.6E-58 T 06-07-2017 IPR012961 ATP-dependent RNA helicase Ski2, C-terminal CAK77_RS10660 475b8bba52c3a1dd6c4d952bde27b33f 922 SMART SM00490 339 431 3.0E-13 T 06-07-2017 IPR001650 Helicase, C-terminal CAK77_RS10660 475b8bba52c3a1dd6c4d952bde27b33f 922 Gene3D G3DSA:3.40.50.300 282 312 4.9E-17 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS10660 475b8bba52c3a1dd6c4d952bde27b33f 922 Gene3D G3DSA:3.40.50.300 354 441 4.9E-17 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS10660 475b8bba52c3a1dd6c4d952bde27b33f 922 Gene3D G3DSA:3.40.50.300 18 200 7.5E-34 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS12670 a415121dfc0ce2d6aaf1cadc66efe795 414 Pfam PF00665 Integrase core domain 116 244 1.1E-12 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 CAK77_RS12670 a415121dfc0ce2d6aaf1cadc66efe795 414 SUPERFAMILY SSF53098 144 286 5.88E-13 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAK77_RS12670 a415121dfc0ce2d6aaf1cadc66efe795 414 Gene3D G3DSA:3.30.420.10 117 285 1.7E-12 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAK77_RS14270 a415121dfc0ce2d6aaf1cadc66efe795 414 Pfam PF00665 Integrase core domain 116 244 1.1E-12 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 CAK77_RS14270 a415121dfc0ce2d6aaf1cadc66efe795 414 SUPERFAMILY SSF53098 144 286 5.88E-13 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAK77_RS14270 a415121dfc0ce2d6aaf1cadc66efe795 414 Gene3D G3DSA:3.30.420.10 117 285 1.7E-12 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAK77_RS00870 a415121dfc0ce2d6aaf1cadc66efe795 414 Pfam PF00665 Integrase core domain 116 244 1.1E-12 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 CAK77_RS00870 a415121dfc0ce2d6aaf1cadc66efe795 414 SUPERFAMILY SSF53098 144 286 5.88E-13 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAK77_RS00870 a415121dfc0ce2d6aaf1cadc66efe795 414 Gene3D G3DSA:3.30.420.10 117 285 1.7E-12 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAK77_RS02760 9e51fb81d6e9a6f7f1e6010b2fdba037 220 SUPERFAMILY SSF46689 25 83 1.75E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS02760 9e51fb81d6e9a6f7f1e6010b2fdba037 220 Pfam PF00440 Bacterial regulatory proteins, tetR family 32 78 2.1E-18 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS02760 9e51fb81d6e9a6f7f1e6010b2fdba037 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 45 8.1E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS02760 9e51fb81d6e9a6f7f1e6010b2fdba037 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 53 76 8.1E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS02760 9e51fb81d6e9a6f7f1e6010b2fdba037 220 Gene3D G3DSA:1.10.357.10 24 213 1.5E-23 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS02905 0ca8043384660c969bfcf5c73434cca6 204 Pfam PF00484 Carbonic anhydrase 46 193 4.7E-35 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CAK77_RS02905 0ca8043384660c969bfcf5c73434cca6 204 ProSitePatterns PS00704 Prokaryotic-type carbonic anhydrases signature 1. 50 57 - T 06-07-2017 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CAK77_RS02905 0ca8043384660c969bfcf5c73434cca6 204 SUPERFAMILY SSF53056 3 198 2.88E-50 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CAK77_RS02905 0ca8043384660c969bfcf5c73434cca6 204 Gene3D G3DSA:3.40.1050.10 3 195 9.1E-50 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CAK77_RS02905 0ca8043384660c969bfcf5c73434cca6 204 SMART SM00947 38 197 3.5E-45 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CAK77_RS04040 0a8bb9918f09817475269d31065c051d 391 Gene3D G3DSA:1.10.1200.80 279 349 3.9E-21 T 06-07-2017 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 CAK77_RS04040 0a8bb9918f09817475269d31065c051d 391 Pfam PF01207 Dihydrouridine synthase (Dus) 27 341 5.4E-109 T 06-07-2017 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 CAK77_RS04040 0a8bb9918f09817475269d31065c051d 391 PIRSF PIRSF006621 14 353 4.3E-115 T 06-07-2017 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 CAK77_RS04040 0a8bb9918f09817475269d31065c051d 391 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 116 134 - T 06-07-2017 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 CAK77_RS04040 0a8bb9918f09817475269d31065c051d 391 SUPERFAMILY SSF51395 25 342 2.2E-80 T 06-07-2017 CAK77_RS04040 0a8bb9918f09817475269d31065c051d 391 Gene3D G3DSA:3.20.20.70 22 272 6.5E-83 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK77_RS04040 0a8bb9918f09817475269d31065c051d 391 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 17 345 2.5E-121 T 06-07-2017 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 CAK77_RS21130 06a4ebdb88f99ab6482652241c38cdce 259 SUPERFAMILY SSF110399 6 243 9.42E-81 T 06-07-2017 IPR008867 Thiazole biosynthesis GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 CAK77_RS21130 06a4ebdb88f99ab6482652241c38cdce 259 Hamap MF_00443 Thiazole synthase [thiG]. 6 257 41.679 T 06-07-2017 IPR008867 Thiazole biosynthesis GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 CAK77_RS21130 06a4ebdb88f99ab6482652241c38cdce 259 Gene3D G3DSA:3.20.20.70 9 256 4.5E-56 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK77_RS21130 06a4ebdb88f99ab6482652241c38cdce 259 Pfam PF05690 Thiazole biosynthesis protein ThiG 9 251 2.5E-106 T 06-07-2017 CAK77_RS12890 6312d17ee14ee8724ad80080c02e50cf 239 Pfam PF09529 Integral membrane protein (intg_mem_TP0381) 12 221 7.4E-56 T 06-07-2017 IPR011737 Conserved hypothetical protein CHP02206, TP0381 CAK77_RS12890 6312d17ee14ee8724ad80080c02e50cf 239 TIGRFAM TIGR02206 intg_mem_TP0381: conserved hypothetical integral membrane protein TIGR02206 8 226 4.5E-66 T 06-07-2017 IPR011737 Conserved hypothetical protein CHP02206, TP0381 CAK77_RS03820 bfbce741d008dc2e13aaf3cce1227502 213 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 24 205 1.1E-27 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS03820 bfbce741d008dc2e13aaf3cce1227502 213 SUPERFAMILY SSF88659 138 206 1.87E-11 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS03820 bfbce741d008dc2e13aaf3cce1227502 213 Gene3D G3DSA:1.10.10.10 144 208 5.1E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS03820 bfbce741d008dc2e13aaf3cce1227502 213 Pfam PF08281 Sigma-70, region 4 155 199 7.6E-10 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS03820 bfbce741d008dc2e13aaf3cce1227502 213 SUPERFAMILY SSF88946 8 98 1.44E-25 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS03820 bfbce741d008dc2e13aaf3cce1227502 213 Pfam PF04542 Sigma-70 region 2 28 95 3.7E-17 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS03820 bfbce741d008dc2e13aaf3cce1227502 213 Gene3D G3DSA:1.10.1740.10 8 100 1.1E-27 T 06-07-2017 CAK77_RS11130 fdf76157bd47439930a6e5fbe1abad2a 316 PRINTS PR00111 Alpha/beta hydrolase fold signature 133 146 1.4E-10 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS11130 fdf76157bd47439930a6e5fbe1abad2a 316 PRINTS PR00111 Alpha/beta hydrolase fold signature 73 88 1.4E-10 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS11130 fdf76157bd47439930a6e5fbe1abad2a 316 PRINTS PR00111 Alpha/beta hydrolase fold signature 119 132 1.4E-10 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS11130 fdf76157bd47439930a6e5fbe1abad2a 316 PRINTS PR00111 Alpha/beta hydrolase fold signature 247 261 1.4E-10 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS11130 fdf76157bd47439930a6e5fbe1abad2a 316 SUPERFAMILY SSF53474 28 302 2.99E-49 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS11130 fdf76157bd47439930a6e5fbe1abad2a 316 Gene3D G3DSA:3.40.50.1820 29 301 2.2E-47 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS11130 fdf76157bd47439930a6e5fbe1abad2a 316 Pfam PF00561 alpha/beta hydrolase fold 50 148 1.8E-15 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS16930 e3805bf775ea07227a703ab4d2b4ebf0 324 Gene3D G3DSA:1.10.620.20 3 285 6.4E-97 T 06-07-2017 IPR012348 Ribonucleotide reductase-related GO:0016491|GO:0055114 Reactome: R-HSA-499943 CAK77_RS16930 e3805bf775ea07227a703ab4d2b4ebf0 324 Pfam PF00268 Ribonucleotide reductase, small chain 14 285 5.7E-91 T 06-07-2017 IPR000358 Ribonucleotide reductase small subunit GO:0009186|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CAK77_RS16930 e3805bf775ea07227a703ab4d2b4ebf0 324 PIRSF PIRSF000355 2 321 8.3E-84 T 06-07-2017 IPR000358 Ribonucleotide reductase small subunit GO:0009186|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CAK77_RS16930 e3805bf775ea07227a703ab4d2b4ebf0 324 SUPERFAMILY SSF47240 10 324 3.52E-109 T 06-07-2017 IPR009078 Ferritin-like superfamily CAK77_RS16930 e3805bf775ea07227a703ab4d2b4ebf0 324 TIGRFAM TIGR04171 RNR_1b_NrdF: ribonucleoside-diphosphate reductase, class 1b, beta subunit 12 324 2.2E-149 T 06-07-2017 IPR026494 Ribonucleoside reductase subunit beta, NrdF GO:0005971|GO:0009263 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CAK77_RS16930 e3805bf775ea07227a703ab4d2b4ebf0 324 ProSitePatterns PS00368 Ribonucleotide reductase small subunit signature. 102 118 - T 06-07-2017 IPR030475 Ribonucleotide reductase small subunit, acitve site KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CAK77_RS08255 d5dab8cabf41059ccb50f7eee91361fc 442 PIRSF PIRSF000151 27 441 8.4E-168 T 06-07-2017 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 CAK77_RS08255 d5dab8cabf41059ccb50f7eee91361fc 442 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 41 430 9.5E-140 T 06-07-2017 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CAK77_RS08255 d5dab8cabf41059ccb50f7eee91361fc 442 Gene3D G3DSA:3.40.309.10 255 398 1.7E-37 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAK77_RS08255 d5dab8cabf41059ccb50f7eee91361fc 442 Pfam PF00171 Aldehyde dehydrogenase family 26 312 1.6E-13 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAK77_RS08255 d5dab8cabf41059ccb50f7eee91361fc 442 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 33 440 41.19 T 06-07-2017 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CAK77_RS08255 d5dab8cabf41059ccb50f7eee91361fc 442 Gene3D G3DSA:3.40.605.10 399 440 1.7E-97 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAK77_RS08255 d5dab8cabf41059ccb50f7eee91361fc 442 Gene3D G3DSA:3.40.605.10 33 252 1.7E-97 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAK77_RS08255 d5dab8cabf41059ccb50f7eee91361fc 442 SUPERFAMILY SSF53720 34 440 1.03E-110 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAK77_RS08255 d5dab8cabf41059ccb50f7eee91361fc 442 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 347 368 - T 06-07-2017 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CAK77_RS07380 12d00a84e78bad83702f7cac34ca2db8 735 PIRSF PIRSF000463 11 734 9.1E-279 T 06-07-2017 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 CAK77_RS07380 12d00a84e78bad83702f7cac34ca2db8 735 Hamap MF_00685 1,4-alpha-glucan branching enzyme GlgB [glgB]. 106 731 43.18 T 06-07-2017 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 CAK77_RS07380 12d00a84e78bad83702f7cac34ca2db8 735 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 633 730 8.4E-22 T 06-07-2017 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 CAK77_RS07380 12d00a84e78bad83702f7cac34ca2db8 735 Pfam PF00128 Alpha amylase, catalytic domain 281 349 3.5E-6 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CAK77_RS07380 12d00a84e78bad83702f7cac34ca2db8 735 Gene3D G3DSA:3.20.20.80 247 615 5.4E-90 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAK77_RS07380 12d00a84e78bad83702f7cac34ca2db8 735 Gene3D G3DSA:2.60.40.10 118 230 6.1E-37 T 06-07-2017 IPR013783 Immunoglobulin-like fold CAK77_RS07380 12d00a84e78bad83702f7cac34ca2db8 735 Gene3D G3DSA:2.60.40.10 18 111 4.1E-13 T 06-07-2017 IPR013783 Immunoglobulin-like fold CAK77_RS07380 12d00a84e78bad83702f7cac34ca2db8 735 SUPERFAMILY SSF51011 628 731 2.52E-32 T 06-07-2017 CAK77_RS07380 12d00a84e78bad83702f7cac34ca2db8 735 SUPERFAMILY SSF81296 122 229 1.12E-30 T 06-07-2017 IPR014756 Immunoglobulin E-set CAK77_RS07380 12d00a84e78bad83702f7cac34ca2db8 735 SUPERFAMILY SSF51445 181 621 3.81E-108 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily CAK77_RS07380 12d00a84e78bad83702f7cac34ca2db8 735 SUPERFAMILY SSF81296 19 119 1.08E-16 T 06-07-2017 IPR014756 Immunoglobulin E-set CAK77_RS07380 12d00a84e78bad83702f7cac34ca2db8 735 Gene3D G3DSA:2.60.40.1180 628 730 1.0E-37 T 06-07-2017 IPR013780 Glycosyl hydrolase, all-beta CAK77_RS07380 12d00a84e78bad83702f7cac34ca2db8 735 TIGRFAM TIGR01515 branching_enzym: 1,4-alpha-glucan branching enzyme 114 728 1.6E-267 T 06-07-2017 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 CAK77_RS07380 12d00a84e78bad83702f7cac34ca2db8 735 SMART SM00642 259 607 2.0E-8 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CAK77_RS07380 12d00a84e78bad83702f7cac34ca2db8 735 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 130 216 3.7E-22 T 06-07-2017 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 CAK77_RS10355 172d9b975128c0d0e5262565077a7112 227 Gene3D G3DSA:3.40.50.1000 90 196 6.9E-38 T 06-07-2017 IPR023214 HAD-like domain CAK77_RS10355 172d9b975128c0d0e5262565077a7112 227 Gene3D G3DSA:3.40.50.1000 2 15 6.9E-38 T 06-07-2017 IPR023214 HAD-like domain CAK77_RS10355 172d9b975128c0d0e5262565077a7112 227 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 1 12 6.3E-6 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAK77_RS10355 172d9b975128c0d0e5262565077a7112 227 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 147 167 6.3E-6 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAK77_RS10355 172d9b975128c0d0e5262565077a7112 227 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 129 145 6.3E-6 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAK77_RS10355 172d9b975128c0d0e5262565077a7112 227 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 99 112 6.3E-6 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAK77_RS10355 172d9b975128c0d0e5262565077a7112 227 Pfam PF13419 Haloacid dehalogenase-like hydrolase 4 185 3.1E-26 T 06-07-2017 IPR023214 HAD-like domain CAK77_RS10355 172d9b975128c0d0e5262565077a7112 227 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 107 185 4.6E-12 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAK77_RS10355 172d9b975128c0d0e5262565077a7112 227 SUPERFAMILY SSF56784 2 189 1.33E-43 T 06-07-2017 IPR023214 HAD-like domain CAK77_RS11105 badb6ec50e56ef0aaff736cca074885c 580 SUPERFAMILY SSF51905 8 259 2.75E-28 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS11105 badb6ec50e56ef0aaff736cca074885c 580 Pfam PF04820 Tryptophan halogenase 126 373 2.6E-6 T 06-07-2017 IPR006905 Tryptophan halogenase CAK77_RS11105 badb6ec50e56ef0aaff736cca074885c 580 Pfam PF04820 Tryptophan halogenase 11 58 1.1E-7 T 06-07-2017 IPR006905 Tryptophan halogenase CAK77_RS11105 badb6ec50e56ef0aaff736cca074885c 580 Gene3D G3DSA:3.50.50.60 122 202 5.2E-27 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS11105 badb6ec50e56ef0aaff736cca074885c 580 Gene3D G3DSA:3.50.50.60 11 74 5.2E-27 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS11105 badb6ec50e56ef0aaff736cca074885c 580 Gene3D G3DSA:3.50.50.60 316 351 5.2E-27 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS11105 badb6ec50e56ef0aaff736cca074885c 580 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 174 189 1.8E-7 T 06-07-2017 CAK77_RS11105 badb6ec50e56ef0aaff736cca074885c 580 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 11 33 1.8E-7 T 06-07-2017 CAK77_RS05060 00bb0a8578ae6c75556b7228f33b988a 375 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 14 304 1.4E-45 T 06-07-2017 IPR005693 Virulence factor Mce protein CAK77_RS05060 00bb0a8578ae6c75556b7228f33b988a 375 Pfam PF02470 MlaD protein 38 113 1.7E-12 T 06-07-2017 IPR003399 Mce/MlaD CAK77_RS20845 8147e7b262ae28323020b5b64a774307 365 SUPERFAMILY SSF47203 225 361 3.38E-37 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS20845 8147e7b262ae28323020b5b64a774307 365 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 224 360 9.9E-32 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS20845 8147e7b262ae28323020b5b64a774307 365 Gene3D G3DSA:2.40.110.10 135 215 7.8E-10 T 06-07-2017 CAK77_RS20845 8147e7b262ae28323020b5b64a774307 365 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 117 4.8E-12 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS20845 8147e7b262ae28323020b5b64a774307 365 SUPERFAMILY SSF56645 1 213 6.41E-33 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK77_RS20845 8147e7b262ae28323020b5b64a774307 365 Gene3D G3DSA:1.10.540.10 1 119 2.6E-18 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS20845 8147e7b262ae28323020b5b64a774307 365 Gene3D G3DSA:1.20.140.10 225 362 5.7E-37 T 06-07-2017 CAK77_RS04005 a3d1949f62208d39b17e53c931b49772 376 SUPERFAMILY SSF53850 57 376 4.89E-80 T 06-07-2017 CAK77_RS04005 a3d1949f62208d39b17e53c931b49772 376 Gene3D G3DSA:3.40.190.10 234 373 9.1E-24 T 06-07-2017 CAK77_RS04005 a3d1949f62208d39b17e53c931b49772 376 Gene3D G3DSA:3.40.190.10 56 204 2.0E-44 T 06-07-2017 CAK77_RS04005 a3d1949f62208d39b17e53c931b49772 376 Pfam PF12849 PBP superfamily domain 51 345 6.3E-58 T 06-07-2017 IPR024370 PBP domain CAK77_RS04005 a3d1949f62208d39b17e53c931b49772 376 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 58 374 2.9E-85 T 06-07-2017 IPR005673 ABC transporter, phosphate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 CAK77_RS04005 a3d1949f62208d39b17e53c931b49772 376 PIRSF PIRSF002756 9 376 6.6E-117 T 06-07-2017 IPR005673 ABC transporter, phosphate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 CAK77_RS05510 677ebb0f2c04365f2fadec6de4f38174 231 SUPERFAMILY SSF52317 1 227 1.15E-70 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAK77_RS05510 677ebb0f2c04365f2fadec6de4f38174 231 Pfam PF01965 DJ-1/PfpI family 27 224 3.7E-15 T 06-07-2017 IPR002818 DJ-1/PfpI CAK77_RS05510 677ebb0f2c04365f2fadec6de4f38174 231 Gene3D G3DSA:3.40.50.880 1 228 3.3E-80 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAK77_RS18875 13ea418acc0b591216216da98a4f50e8 181 SUPERFAMILY SSF52540 2 179 1.89E-41 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS18875 13ea418acc0b591216216da98a4f50e8 181 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 06-07-2017 CAK77_RS18875 13ea418acc0b591216216da98a4f50e8 181 Hamap MF_00235 Adenylate kinase [adk]. 1 180 45.4 T 06-07-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CAK77_RS18875 13ea418acc0b591216216da98a4f50e8 181 Gene3D G3DSA:3.40.50.300 2 178 7.0E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS18875 13ea418acc0b591216216da98a4f50e8 181 Pfam PF00406 Adenylate kinase 5 157 8.3E-55 T 06-07-2017 CAK77_RS18875 13ea418acc0b591216216da98a4f50e8 181 PRINTS PR00094 Adenylate kinase signature 146 160 1.1E-32 T 06-07-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CAK77_RS18875 13ea418acc0b591216216da98a4f50e8 181 PRINTS PR00094 Adenylate kinase signature 81 97 1.1E-32 T 06-07-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CAK77_RS18875 13ea418acc0b591216216da98a4f50e8 181 PRINTS PR00094 Adenylate kinase signature 4 17 1.1E-32 T 06-07-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CAK77_RS18875 13ea418acc0b591216216da98a4f50e8 181 PRINTS PR00094 Adenylate kinase signature 32 46 1.1E-32 T 06-07-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CAK77_RS18875 13ea418acc0b591216216da98a4f50e8 181 PRINTS PR00094 Adenylate kinase signature 129 144 1.1E-32 T 06-07-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CAK77_RS05605 f8fa3915d6c6e65734f900f6c703e32d 301 SMART SM00650 50 225 2.3E-66 T 06-07-2017 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 CAK77_RS05605 f8fa3915d6c6e65734f900f6c703e32d 301 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 66 93 - T 06-07-2017 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 CAK77_RS05605 f8fa3915d6c6e65734f900f6c703e32d 301 Pfam PF00398 Ribosomal RNA adenine dimethylase 38 266 2.6E-38 T 06-07-2017 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm CAK77_RS05605 f8fa3915d6c6e65734f900f6c703e32d 301 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 34 299 46.514 T 06-07-2017 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 CAK77_RS05605 f8fa3915d6c6e65734f900f6c703e32d 301 Gene3D G3DSA:3.40.50.150 22 225 7.5E-66 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS05605 f8fa3915d6c6e65734f900f6c703e32d 301 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 34 296 2.9E-76 T 06-07-2017 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 CAK77_RS05605 f8fa3915d6c6e65734f900f6c703e32d 301 SUPERFAMILY SSF53335 34 296 1.09E-59 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS05605 f8fa3915d6c6e65734f900f6c703e32d 301 Gene3D G3DSA:1.10.8.100 236 296 4.0E-17 T 06-07-2017 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201 CAK77_RS21315 860e960e8acee3bc49d4dc72c09ff47d 297 SUPERFAMILY SSF53335 15 289 1.02E-73 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS21315 860e960e8acee3bc49d4dc72c09ff47d 297 Gene3D G3DSA:3.40.50.150 10 287 2.5E-83 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS21315 860e960e8acee3bc49d4dc72c09ff47d 297 Pfam PF02353 Mycolic acid cyclopropane synthetase 7 285 8.4E-120 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS21315 860e960e8acee3bc49d4dc72c09ff47d 297 PIRSF PIRSF003085 2 293 2.2E-110 T 06-07-2017 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 CAK77_RS12190 b571ba53778dde00b67e0bfb18f540b6 171 SUPERFAMILY SSF50475 13 156 7.85E-32 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS12190 b571ba53778dde00b67e0bfb18f540b6 171 SMART SM00903 19 158 7.6E-23 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 CAK77_RS12190 b571ba53778dde00b67e0bfb18f540b6 171 Gene3D G3DSA:2.30.110.10 15 152 1.3E-34 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS12190 b571ba53778dde00b67e0bfb18f540b6 171 Pfam PF01613 Flavin reductase like domain 19 147 8.2E-21 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 CAK77_RS17610 43121fd38fc86a691ed1f84894726d4b 1058 Gene3D G3DSA:3.40.50.300 24 154 1.6E-34 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS17610 43121fd38fc86a691ed1f84894726d4b 1058 Gene3D G3DSA:3.40.50.300 195 299 1.6E-34 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS17610 43121fd38fc86a691ed1f84894726d4b 1058 Pfam PF00580 UvrD/REP helicase N-terminal domain 25 299 7.9E-29 T 06-07-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 CAK77_RS17610 43121fd38fc86a691ed1f84894726d4b 1058 Gene3D G3DSA:3.40.50.300 606 719 3.5E-30 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS17610 43121fd38fc86a691ed1f84894726d4b 1058 Gene3D G3DSA:3.40.50.300 314 428 3.5E-30 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS17610 43121fd38fc86a691ed1f84894726d4b 1058 SUPERFAMILY SSF52540 24 718 3.64E-74 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS17610 43121fd38fc86a691ed1f84894726d4b 1058 Pfam PF12705 PD-(D/E)XK nuclease superfamily 804 1047 1.7E-41 T 06-07-2017 CAK77_RS17610 43121fd38fc86a691ed1f84894726d4b 1058 Pfam PF13361 UvrD-like helicase C-terminal domain 557 693 1.2E-7 T 06-07-2017 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CAK77_RS01015 672cefcbd4b3a11c07dbc72ced3e46d3 412 SUPERFAMILY SSF51971 18 289 2.12E-45 T 06-07-2017 CAK77_RS01015 672cefcbd4b3a11c07dbc72ced3e46d3 412 SUPERFAMILY SSF51971 362 395 2.12E-45 T 06-07-2017 CAK77_RS01015 672cefcbd4b3a11c07dbc72ced3e46d3 412 TIGRFAM TIGR00031 UDP-GALP_mutase: UDP-galactopyranose mutase 18 395 4.6E-103 T 06-07-2017 IPR004379 UDP-galactopyranose mutase GO:0008767 KEGG: 00052+5.4.99.9|KEGG: 00520+5.4.99.9|MetaCyc: PWY-6397|MetaCyc: PWY-7328|MetaCyc: PWY-7622 CAK77_RS01015 672cefcbd4b3a11c07dbc72ced3e46d3 412 Pfam PF03275 UDP-galactopyranose mutase 167 377 4.9E-80 T 06-07-2017 IPR015899 UDP-galactopyranose mutase, C-terminal GO:0008767 KEGG: 00052+5.4.99.9|KEGG: 00520+5.4.99.9|MetaCyc: PWY-6397|MetaCyc: PWY-7328|MetaCyc: PWY-7622 CAK77_RS01015 672cefcbd4b3a11c07dbc72ced3e46d3 412 Pfam PF13450 NAD(P)-binding Rossmann-like domain 23 92 1.0E-17 T 06-07-2017 CAK77_RS01015 672cefcbd4b3a11c07dbc72ced3e46d3 412 Gene3D G3DSA:3.40.50.720 202 279 2.9E-46 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS01015 672cefcbd4b3a11c07dbc72ced3e46d3 412 Gene3D G3DSA:3.40.50.720 352 398 2.9E-46 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS01015 672cefcbd4b3a11c07dbc72ced3e46d3 412 Gene3D G3DSA:3.40.50.720 16 98 2.9E-46 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS01015 672cefcbd4b3a11c07dbc72ced3e46d3 412 SUPERFAMILY SSF54373 270 341 3.34E-24 T 06-07-2017 CAK77_RS20335 928e1c04e659a57699296fa7e35fa709 412 SUPERFAMILY SSF53067 96 384 1.56E-26 T 06-07-2017 CAK77_RS20335 928e1c04e659a57699296fa7e35fa709 412 Gene3D G3DSA:1.10.10.10 24 91 3.1E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS20335 928e1c04e659a57699296fa7e35fa709 412 SUPERFAMILY SSF46785 26 90 7.21E-8 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS20335 928e1c04e659a57699296fa7e35fa709 412 Gene3D G3DSA:3.30.420.40 237 361 1.9E-19 T 06-07-2017 CAK77_RS20335 928e1c04e659a57699296fa7e35fa709 412 Pfam PF00480 ROK family 97 355 1.0E-17 T 06-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 CAK77_RS20335 928e1c04e659a57699296fa7e35fa709 412 Gene3D G3DSA:3.30.420.40 95 236 2.6E-22 T 06-07-2017 CAK77_RS06350 13fdea62c9b8e6277e759463a29d8989 357 Gene3D G3DSA:1.10.150.300 131 196 3.0E-18 T 06-07-2017 IPR023192 TGS-like domain CAK77_RS06350 13fdea62c9b8e6277e759463a29d8989 357 Pfam PF06071 Protein of unknown function (DUF933) 273 356 3.1E-39 T 06-07-2017 IPR013029 Domain of unknown function DUF933 CAK77_RS06350 13fdea62c9b8e6277e759463a29d8989 357 Gene3D G3DSA:3.10.20.30 259 357 2.0E-46 T 06-07-2017 IPR012675 Beta-grasp domain CAK77_RS06350 13fdea62c9b8e6277e759463a29d8989 357 SUPERFAMILY SSF52540 3 295 4.18E-73 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS06350 13fdea62c9b8e6277e759463a29d8989 357 SUPERFAMILY SSF81271 273 357 6.76E-35 T 06-07-2017 IPR012676 TGS-like KEGG: 00970+6.1.1.3 CAK77_RS06350 13fdea62c9b8e6277e759463a29d8989 357 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 3 357 3.7E-130 T 06-07-2017 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 CAK77_RS06350 13fdea62c9b8e6277e759463a29d8989 357 PIRSF PIRSF006641 1 357 4.3E-139 T 06-07-2017 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 CAK77_RS06350 13fdea62c9b8e6277e759463a29d8989 357 Pfam PF01926 50S ribosome-binding GTPase 5 115 1.8E-22 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 CAK77_RS06350 13fdea62c9b8e6277e759463a29d8989 357 Gene3D G3DSA:3.40.50.300 3 130 7.4E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS06350 13fdea62c9b8e6277e759463a29d8989 357 Gene3D G3DSA:3.40.50.300 197 258 7.4E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS06350 13fdea62c9b8e6277e759463a29d8989 357 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 357 42.37 T 06-07-2017 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 CAK77_RS06350 13fdea62c9b8e6277e759463a29d8989 357 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 2.7E-34 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 CAK77_RS06350 13fdea62c9b8e6277e759463a29d8989 357 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 2.7E-34 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 CAK77_RS06350 13fdea62c9b8e6277e759463a29d8989 357 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 2.7E-34 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 CAK77_RS06350 13fdea62c9b8e6277e759463a29d8989 357 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 2.7E-34 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 CAK77_RS16555 bbddee3e2767376becbc81c4c5d6a53a 390 SUPERFAMILY SSF54373 172 271 3.14E-21 T 06-07-2017 CAK77_RS16555 bbddee3e2767376becbc81c4c5d6a53a 390 Pfam PF01494 FAD binding domain 2 343 2.1E-25 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 CAK77_RS16555 bbddee3e2767376becbc81c4c5d6a53a 390 Gene3D G3DSA:3.50.50.60 1 172 1.0E-43 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS16555 bbddee3e2767376becbc81c4c5d6a53a 390 Gene3D G3DSA:3.50.50.60 266 351 1.0E-43 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS16555 bbddee3e2767376becbc81c4c5d6a53a 390 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 1.1E-20 T 06-07-2017 CAK77_RS16555 bbddee3e2767376becbc81c4c5d6a53a 390 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 146 161 1.1E-20 T 06-07-2017 CAK77_RS16555 bbddee3e2767376becbc81c4c5d6a53a 390 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 294 310 1.1E-20 T 06-07-2017 CAK77_RS16555 bbddee3e2767376becbc81c4c5d6a53a 390 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 279 294 1.1E-20 T 06-07-2017 CAK77_RS16555 bbddee3e2767376becbc81c4c5d6a53a 390 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 329 345 1.1E-20 T 06-07-2017 CAK77_RS16555 bbddee3e2767376becbc81c4c5d6a53a 390 SUPERFAMILY SSF51905 266 359 1.2E-63 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS16555 bbddee3e2767376becbc81c4c5d6a53a 390 SUPERFAMILY SSF51905 1 167 1.2E-63 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS02030 7aeb3aa67befbd014f47dd4dc61796af 238 Gene3D G3DSA:3.40.630.30 113 207 5.4E-13 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS02030 7aeb3aa67befbd014f47dd4dc61796af 238 Pfam PF00583 Acetyltransferase (GNAT) family 154 218 2.0E-4 T 06-07-2017 IPR000182 GNAT domain GO:0008080 CAK77_RS02030 7aeb3aa67befbd014f47dd4dc61796af 238 SUPERFAMILY SSF55729 101 222 1.18E-14 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS11975 4aabfe3a70ab55f6f9868bc1f153101c 216 SUPERFAMILY SSF52096 4 214 3.17E-38 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS11975 4aabfe3a70ab55f6f9868bc1f153101c 216 Pfam PF00378 Enoyl-CoA hydratase/isomerase 41 214 1.2E-21 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAK77_RS11975 4aabfe3a70ab55f6f9868bc1f153101c 216 Gene3D G3DSA:3.90.226.10 8 192 1.2E-34 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS04610 f707dd39bb0f99b99db275b65a7eb60c 486 Pfam PF00668 Condensation domain 83 351 1.2E-9 T 06-07-2017 IPR001242 Condensation domain CAK77_RS04610 f707dd39bb0f99b99db275b65a7eb60c 486 SUPERFAMILY SSF52777 54 225 9.64E-14 T 06-07-2017 CAK77_RS04610 f707dd39bb0f99b99db275b65a7eb60c 486 SUPERFAMILY SSF52777 243 479 1.22E-20 T 06-07-2017 CAK77_RS05100 16e429ae4606b1ee5ce98f3c2898caad 204 Gene3D G3DSA:3.40.50.620 57 99 9.7E-6 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS05100 16e429ae4606b1ee5ce98f3c2898caad 204 Pfam PF02698 DUF218 domain 64 171 3.3E-6 T 06-07-2017 IPR003848 Domain of unknown function DUF218 CAK77_RS22755 ae9237cbeacc9b17280bc2ca4c3d8d54 160 Gene3D G3DSA:3.30.530.20 1 143 5.6E-16 T 06-07-2017 IPR023393 START-like domain CAK77_RS22755 ae9237cbeacc9b17280bc2ca4c3d8d54 160 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 10 136 3.7E-11 T 06-07-2017 IPR005031 Coenzyme Q-binding protein COQ10, START domain CAK77_RS22755 ae9237cbeacc9b17280bc2ca4c3d8d54 160 SUPERFAMILY SSF55961 1 145 1.33E-25 T 06-07-2017 CAK77_RS15530 08f41eb105633b1a1867b84674be20b3 252 SUPERFAMILY SSF52096 3 240 1.23E-66 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS15530 08f41eb105633b1a1867b84674be20b3 252 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 238 3.7E-50 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAK77_RS15530 08f41eb105633b1a1867b84674be20b3 252 Gene3D G3DSA:3.90.226.10 5 236 2.2E-65 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS09225 911079304bd97bcc923731be052245f6 267 Pfam PF10615 Protein of unknown function (DUF2470) 184 258 2.1E-14 T 06-07-2017 IPR019595 Domain of unknown function DUF2470 CAK77_RS09225 911079304bd97bcc923731be052245f6 267 Gene3D G3DSA:2.30.110.10 11 172 9.9E-46 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS09225 911079304bd97bcc923731be052245f6 267 SUPERFAMILY SSF50475 29 262 1.43E-46 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS09225 911079304bd97bcc923731be052245f6 267 Gene3D G3DSA:3.20.180.10 178 263 1.9E-14 T 06-07-2017 IPR019595 Domain of unknown function DUF2470 CAK77_RS09225 911079304bd97bcc923731be052245f6 267 Pfam PF13883 Pyridoxamine 5'-phosphate oxidase 27 173 4.2E-13 T 06-07-2017 CAK77_RS12620 15d24b6b1868eee00be0234dfcbacd00 864 Pfam PF04851 Type III restriction enzyme, res subunit 128 331 2.4E-30 T 06-07-2017 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CAK77_RS12620 15d24b6b1868eee00be0234dfcbacd00 864 Gene3D G3DSA:3.40.50.300 127 210 5.4E-26 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS12620 15d24b6b1868eee00be0234dfcbacd00 864 Gene3D G3DSA:3.40.50.300 278 342 5.4E-26 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS12620 15d24b6b1868eee00be0234dfcbacd00 864 SMART SM00490 456 540 0.003 T 06-07-2017 IPR001650 Helicase, C-terminal CAK77_RS12620 15d24b6b1868eee00be0234dfcbacd00 864 Pfam PF00271 Helicase conserved C-terminal domain 483 538 7.8E-5 T 06-07-2017 IPR001650 Helicase, C-terminal CAK77_RS12620 15d24b6b1868eee00be0234dfcbacd00 864 SUPERFAMILY SSF52540 399 541 2.74E-27 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS12620 15d24b6b1868eee00be0234dfcbacd00 864 SUPERFAMILY SSF52540 142 199 2.74E-27 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS12620 15d24b6b1868eee00be0234dfcbacd00 864 SUPERFAMILY SSF52540 244 333 2.74E-27 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS12620 15d24b6b1868eee00be0234dfcbacd00 864 Gene3D G3DSA:3.40.50.300 422 540 2.0E-9 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS12620 15d24b6b1868eee00be0234dfcbacd00 864 SMART SM00487 125 358 5.8E-16 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain CAK77_RS12620 15d24b6b1868eee00be0234dfcbacd00 864 Pfam PF08463 EcoEI R protein C-terminal 699 861 5.0E-36 T 06-07-2017 IPR013670 EcoEI R protein C-terminal domain GO:0003677|GO:0003824|GO:0006304 CAK77_RS09925 bc2c5e4cc364ce56ce01a1ee93b76ef6 145 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 24 137 1.2E-21 T 06-07-2017 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-75105 CAK77_RS09925 bc2c5e4cc364ce56ce01a1ee93b76ef6 145 Pfam PF03061 Thioesterase superfamily 54 131 7.8E-13 T 06-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 CAK77_RS09925 bc2c5e4cc364ce56ce01a1ee93b76ef6 145 Gene3D G3DSA:3.10.129.10 6 142 2.3E-32 T 06-07-2017 IPR029069 HotDog domain CAK77_RS09925 bc2c5e4cc364ce56ce01a1ee93b76ef6 145 SUPERFAMILY SSF54637 16 141 6.23E-28 T 06-07-2017 IPR029069 HotDog domain CAK77_RS07155 1b3098163802e53e6b49de367d8f4b21 188 Gene3D G3DSA:3.40.50.620 41 163 1.6E-21 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS07155 1b3098163802e53e6b49de367d8f4b21 188 Pfam PF02698 DUF218 domain 42 164 4.0E-23 T 06-07-2017 IPR003848 Domain of unknown function DUF218 CAK77_RS18285 3ba146e49c941abc41e6e5e23baf48d7 429 TIGRFAM TIGR02644 Y_phosphoryl: pyrimidine-nucleoside phosphorylase 11 413 8.5E-156 T 06-07-2017 IPR018090 Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic GO:0006213|GO:0016154 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181|Reactome: R-HSA-73614|Reactome: R-HSA-73621 CAK77_RS18285 3ba146e49c941abc41e6e5e23baf48d7 429 SUPERFAMILY SSF54680 328 427 3.27E-23 T 06-07-2017 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CAK77_RS18285 3ba146e49c941abc41e6e5e23baf48d7 429 SUPERFAMILY SSF47648 7 75 1.16E-18 T 06-07-2017 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CAK77_RS18285 3ba146e49c941abc41e6e5e23baf48d7 429 Pfam PF02885 Glycosyl transferase family, helical bundle domain 11 72 1.2E-17 T 06-07-2017 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CAK77_RS18285 3ba146e49c941abc41e6e5e23baf48d7 429 Pfam PF00591 Glycosyl transferase family, a/b domain 83 290 5.7E-36 T 06-07-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CAK77_RS18285 3ba146e49c941abc41e6e5e23baf48d7 429 Gene3D G3DSA:3.40.1030.10 76 322 6.1E-101 T 06-07-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CAK77_RS18285 3ba146e49c941abc41e6e5e23baf48d7 429 PIRSF PIRSF000478 6 427 1.3E-145 T 06-07-2017 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CAK77_RS18285 3ba146e49c941abc41e6e5e23baf48d7 429 SMART SM00941 340 414 1.1E-28 T 06-07-2017 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CAK77_RS18285 3ba146e49c941abc41e6e5e23baf48d7 429 Gene3D G3DSA:1.20.970.10 8 73 1.4E-24 T 06-07-2017 CAK77_RS18285 3ba146e49c941abc41e6e5e23baf48d7 429 Gene3D G3DSA:3.90.1170.30 324 417 1.0E-25 T 06-07-2017 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CAK77_RS18285 3ba146e49c941abc41e6e5e23baf48d7 429 SUPERFAMILY SSF52418 75 322 1.15E-77 T 06-07-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CAK77_RS18285 3ba146e49c941abc41e6e5e23baf48d7 429 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 341 413 2.6E-20 T 06-07-2017 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CAK77_RS18285 3ba146e49c941abc41e6e5e23baf48d7 429 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 116 131 - T 06-07-2017 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CAK77_RS04730 6ae6234fbdd9463a7648aac342d7fa5a 800 Gene3D G3DSA:1.20.1110.10 144 418 5.6E-31 T 06-07-2017 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CAK77_RS04730 6ae6234fbdd9463a7648aac342d7fa5a 800 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 74 333 3.4E-30 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CAK77_RS04730 6ae6234fbdd9463a7648aac342d7fa5a 800 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 495 613 9.6E-27 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CAK77_RS04730 6ae6234fbdd9463a7648aac342d7fa5a 800 SUPERFAMILY SSF81665 10 102 5.36E-60 T 06-07-2017 CAK77_RS04730 6ae6234fbdd9463a7648aac342d7fa5a 800 SUPERFAMILY SSF81665 200 294 5.36E-60 T 06-07-2017 CAK77_RS04730 6ae6234fbdd9463a7648aac342d7fa5a 800 SUPERFAMILY SSF81665 583 787 5.36E-60 T 06-07-2017 CAK77_RS04730 6ae6234fbdd9463a7648aac342d7fa5a 800 Pfam PF00702 haloacid dehalogenase-like hydrolase 296 548 5.6E-19 T 06-07-2017 CAK77_RS04730 6ae6234fbdd9463a7648aac342d7fa5a 800 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 557 569 1.8E-22 T 06-07-2017 CAK77_RS04730 6ae6234fbdd9463a7648aac342d7fa5a 800 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 300 314 1.8E-22 T 06-07-2017 CAK77_RS04730 6ae6234fbdd9463a7648aac342d7fa5a 800 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 458 468 1.8E-22 T 06-07-2017 CAK77_RS04730 6ae6234fbdd9463a7648aac342d7fa5a 800 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 534 553 1.8E-22 T 06-07-2017 CAK77_RS04730 6ae6234fbdd9463a7648aac342d7fa5a 800 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 149 163 1.8E-22 T 06-07-2017 CAK77_RS04730 6ae6234fbdd9463a7648aac342d7fa5a 800 SUPERFAMILY SSF81653 105 196 9.55E-19 T 06-07-2017 CAK77_RS04730 6ae6234fbdd9463a7648aac342d7fa5a 800 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 302 308 - T 06-07-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CAK77_RS04730 6ae6234fbdd9463a7648aac342d7fa5a 800 Pfam PF00122 E1-E2 ATPase 72 291 4.4E-50 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 CAK77_RS04730 6ae6234fbdd9463a7648aac342d7fa5a 800 SUPERFAMILY SSF56784 287 312 1.32E-36 T 06-07-2017 IPR023214 HAD-like domain CAK77_RS04730 6ae6234fbdd9463a7648aac342d7fa5a 800 SUPERFAMILY SSF56784 434 578 1.32E-36 T 06-07-2017 IPR023214 HAD-like domain CAK77_RS04730 6ae6234fbdd9463a7648aac342d7fa5a 800 SUPERFAMILY SSF56784 346 399 1.32E-36 T 06-07-2017 IPR023214 HAD-like domain CAK77_RS04730 6ae6234fbdd9463a7648aac342d7fa5a 800 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 534 550 5.1E-9 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CAK77_RS04730 6ae6234fbdd9463a7648aac342d7fa5a 800 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 506 522 5.1E-9 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CAK77_RS04730 6ae6234fbdd9463a7648aac342d7fa5a 800 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 399 417 5.1E-9 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CAK77_RS04730 6ae6234fbdd9463a7648aac342d7fa5a 800 Gene3D G3DSA:1.20.1110.10 68 99 2.6E-47 T 06-07-2017 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CAK77_RS04730 6ae6234fbdd9463a7648aac342d7fa5a 800 Gene3D G3DSA:1.20.1110.10 503 783 2.6E-47 T 06-07-2017 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CAK77_RS22705 8338c5e60b5dcc374cb2deb53aa80a65 370 Pfam PF09992 Phosphodiester glycosidase 149 345 1.0E-7 T 06-07-2017 IPR018711 Phosphodiester glycosidase CAK77_RS23180 58f51e66a0d9bf48ccb0cad81c0a3fc4 257 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 190 0.0048 T 06-07-2017 CAK77_RS23180 58f51e66a0d9bf48ccb0cad81c0a3fc4 257 SUPERFAMILY SSF51735 4 256 2.62E-54 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS23180 58f51e66a0d9bf48ccb0cad81c0a3fc4 257 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 20 255 3.1E-43 T 06-07-2017 CAK77_RS23180 58f51e66a0d9bf48ccb0cad81c0a3fc4 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 8.7E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS23180 58f51e66a0d9bf48ccb0cad81c0a3fc4 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 8.7E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS23180 58f51e66a0d9bf48ccb0cad81c0a3fc4 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 8.7E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS23180 58f51e66a0d9bf48ccb0cad81c0a3fc4 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 239 8.7E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS23180 58f51e66a0d9bf48ccb0cad81c0a3fc4 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 8.7E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS23180 58f51e66a0d9bf48ccb0cad81c0a3fc4 257 Gene3D G3DSA:3.40.50.720 5 256 2.4E-57 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS09745 840912fe809c9f19f34c0e51886e3360 488 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 13 486 30.644 T 06-07-2017 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK77_RS09745 840912fe809c9f19f34c0e51886e3360 488 Gene3D G3DSA:3.40.50.720 12 101 1.1E-8 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS09745 840912fe809c9f19f34c0e51886e3360 488 Pfam PF02875 Mur ligase family, glutamate ligase domain 319 387 2.7E-7 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CAK77_RS09745 840912fe809c9f19f34c0e51886e3360 488 SUPERFAMILY SSF51984 12 102 3.14E-8 T 06-07-2017 CAK77_RS09745 840912fe809c9f19f34c0e51886e3360 488 Pfam PF08245 Mur ligase middle domain 125 297 1.6E-19 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAK77_RS09745 840912fe809c9f19f34c0e51886e3360 488 Gene3D G3DSA:3.40.1190.10 102 316 1.9E-54 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAK77_RS09745 840912fe809c9f19f34c0e51886e3360 488 SUPERFAMILY SSF53244 319 404 8.7E-32 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CAK77_RS09745 840912fe809c9f19f34c0e51886e3360 488 SUPERFAMILY SSF53244 439 486 8.7E-32 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CAK77_RS09745 840912fe809c9f19f34c0e51886e3360 488 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 14 484 1.1E-114 T 06-07-2017 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK77_RS09745 840912fe809c9f19f34c0e51886e3360 488 Gene3D G3DSA:3.90.190.20 319 483 1.2E-42 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CAK77_RS09745 840912fe809c9f19f34c0e51886e3360 488 SUPERFAMILY SSF53623 119 315 5.36E-42 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAK77_RS18925 d29a8cd7215cbf8f77138ef6269408d9 146 ProSitePatterns PS00475 Ribosomal protein L15 signature. 110 140 - T 06-07-2017 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK77_RS18925 d29a8cd7215cbf8f77138ef6269408d9 146 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 28 143 2.3E-32 T 06-07-2017 IPR021131 Ribosomal protein L18e/L15P CAK77_RS18925 d29a8cd7215cbf8f77138ef6269408d9 146 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 5 146 19.655 T 06-07-2017 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 CAK77_RS18925 d29a8cd7215cbf8f77138ef6269408d9 146 SUPERFAMILY SSF52080 6 144 8.37E-41 T 06-07-2017 IPR021131 Ribosomal protein L18e/L15P CAK77_RS18925 d29a8cd7215cbf8f77138ef6269408d9 146 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 4 143 1.1E-47 T 06-07-2017 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS18925 d29a8cd7215cbf8f77138ef6269408d9 146 Gene3D G3DSA:3.100.10.10 33 144 1.0E-33 T 06-07-2017 CAK77_RS13025 40d957b8dfb04fdc053bd1e06ccc5cb8 511 TIGRFAM TIGR00564 trpE_most: anthranilate synthase component I 34 499 1.5E-159 T 06-07-2017 IPR005256 Anthranilate synthase component I, PabB-like GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CAK77_RS13025 40d957b8dfb04fdc053bd1e06ccc5cb8 511 PRINTS PR00095 Anthranilate synthase component I signature 339 352 4.0E-23 T 06-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CAK77_RS13025 40d957b8dfb04fdc053bd1e06ccc5cb8 511 PRINTS PR00095 Anthranilate synthase component I signature 353 366 4.0E-23 T 06-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CAK77_RS13025 40d957b8dfb04fdc053bd1e06ccc5cb8 511 PRINTS PR00095 Anthranilate synthase component I signature 433 447 4.0E-23 T 06-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CAK77_RS13025 40d957b8dfb04fdc053bd1e06ccc5cb8 511 PRINTS PR00095 Anthranilate synthase component I signature 448 462 4.0E-23 T 06-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CAK77_RS13025 40d957b8dfb04fdc053bd1e06ccc5cb8 511 Pfam PF00425 chorismate binding enzyme 233 491 1.6E-92 T 06-07-2017 IPR015890 Chorismate-utilising enzyme, C-terminal CAK77_RS13025 40d957b8dfb04fdc053bd1e06ccc5cb8 511 SUPERFAMILY SSF56322 24 500 5.49E-148 T 06-07-2017 IPR005801 ADC synthase GO:0009058 CAK77_RS13025 40d957b8dfb04fdc053bd1e06ccc5cb8 511 Pfam PF04715 Anthranilate synthase component I, N terminal region 35 176 1.9E-30 T 06-07-2017 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058|GO:0016833 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CAK77_RS13025 40d957b8dfb04fdc053bd1e06ccc5cb8 511 Gene3D G3DSA:3.60.120.10 24 503 3.7E-163 T 06-07-2017 IPR005801 ADC synthase GO:0009058 CAK77_RS14890 56aa91c216bf12fc63c40369f2bd683a 388 SUPERFAMILY SSF50249 2 55 8.0E-10 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS14890 56aa91c216bf12fc63c40369f2bd683a 388 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 237 300 5.3E-5 T 06-07-2017 CAK77_RS14890 56aa91c216bf12fc63c40369f2bd683a 388 SUPERFAMILY SSF53335 67 388 1.39E-37 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS14890 56aa91c216bf12fc63c40369f2bd683a 388 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 316 388 2.5E-8 T 06-07-2017 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 CAK77_RS14890 56aa91c216bf12fc63c40369f2bd683a 388 Gene3D G3DSA:3.40.50.150 199 388 1.7E-35 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS14890 56aa91c216bf12fc63c40369f2bd683a 388 Gene3D G3DSA:2.40.50.140 1 76 7.4E-22 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS14890 56aa91c216bf12fc63c40369f2bd683a 388 Pfam PF01938 TRAM domain 3 50 1.5E-7 T 06-07-2017 IPR002792 TRAM domain CAK77_RS13975 828caf7daa8432887a2207b2ba689b52 304 SUPERFAMILY SSF54001 14 282 9.67E-39 T 06-07-2017 CAK77_RS13975 828caf7daa8432887a2207b2ba689b52 304 Pfam PF01841 Transglutaminase-like superfamily 149 250 9.4E-23 T 06-07-2017 IPR002931 Transglutaminase-like CAK77_RS13975 828caf7daa8432887a2207b2ba689b52 304 Gene3D G3DSA:3.90.260.10 185 260 2.3E-14 T 06-07-2017 IPR002931 Transglutaminase-like CAK77_RS13975 828caf7daa8432887a2207b2ba689b52 304 Pfam PF08379 Bacterial transglutaminase-like N-terminal region 10 89 5.5E-22 T 06-07-2017 IPR013589 Bacterial transglutaminase-like, N-terminal CAK77_RS13975 828caf7daa8432887a2207b2ba689b52 304 SMART SM00460 182 252 2.4E-20 T 06-07-2017 IPR002931 Transglutaminase-like CAK77_RS03690 192bac2943b68bf63915bcc2dd8e3727 337 SUPERFAMILY SSF46689 287 333 3.81E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS03690 192bac2943b68bf63915bcc2dd8e3727 337 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 299 314 9.5E-6 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CAK77_RS03690 192bac2943b68bf63915bcc2dd8e3727 337 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 314 330 9.5E-6 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CAK77_RS03690 192bac2943b68bf63915bcc2dd8e3727 337 Gene3D G3DSA:1.10.10.60 286 334 2.8E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS03690 192bac2943b68bf63915bcc2dd8e3727 337 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 22 202 5.6E-26 T 06-07-2017 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal CAK77_RS03690 192bac2943b68bf63915bcc2dd8e3727 337 SMART SM00342 247 330 3.7E-21 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK77_RS03690 192bac2943b68bf63915bcc2dd8e3727 337 Pfam PF12833 Helix-turn-helix domain 253 331 2.6E-17 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK77_RS18710 cbd77481c648155f96cba2b2bb56123e 175 Gene3D G3DSA:3.30.230.10 51 175 4.9E-47 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CAK77_RS18710 cbd77481c648155f96cba2b2bb56123e 175 Pfam PF00380 Ribosomal protein S9/S16 55 175 1.2E-41 T 06-07-2017 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 CAK77_RS18710 cbd77481c648155f96cba2b2bb56123e 175 SUPERFAMILY SSF54211 51 175 8.34E-44 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAK77_RS18710 cbd77481c648155f96cba2b2bb56123e 175 ProSitePatterns PS00360 Ribosomal protein S9 signature. 114 132 - T 06-07-2017 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 CAK77_RS18710 cbd77481c648155f96cba2b2bb56123e 175 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 46 175 31.491 T 06-07-2017 IPR023035 Ribosomal protein S9, bacterial/plastid CAK77_RS19930 a92634b0ffd2063822ed6f2688eee354 446 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 20 434 1.0E-184 T 06-07-2017 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 CAK77_RS19930 a92634b0ffd2063822ed6f2688eee354 446 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 19 440 97.164 T 06-07-2017 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 CAK77_RS19930 a92634b0ffd2063822ed6f2688eee354 446 SUPERFAMILY SSF53383 17 436 1.25E-113 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK77_RS19930 a92634b0ffd2063822ed6f2688eee354 446 Gene3D G3DSA:3.90.1150.10 14 85 5.3E-35 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK77_RS19930 a92634b0ffd2063822ed6f2688eee354 446 Gene3D G3DSA:3.90.1150.10 334 436 5.3E-35 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK77_RS19930 a92634b0ffd2063822ed6f2688eee354 446 Pfam PF00202 Aminotransferase class-III 49 433 7.3E-83 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAK77_RS19930 a92634b0ffd2063822ed6f2688eee354 446 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 250 286 - T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAK77_RS19930 a92634b0ffd2063822ed6f2688eee354 446 Gene3D G3DSA:3.40.640.10 86 330 7.5E-75 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK77_RS17030 38235b3dca8685ed43afd03c3452b3f1 182 Gene3D G3DSA:3.40.50.360 8 180 5.3E-45 T 06-07-2017 IPR029039 Flavoprotein-like domain CAK77_RS17030 38235b3dca8685ed43afd03c3452b3f1 182 SUPERFAMILY SSF52218 8 179 4.19E-41 T 06-07-2017 IPR029039 Flavoprotein-like domain CAK77_RS17030 38235b3dca8685ed43afd03c3452b3f1 182 Pfam PF03358 NADPH-dependent FMN reductase 9 153 1.9E-33 T 06-07-2017 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CAK77_RS20815 5f3a9c603e998a3ab203934703e510f5 399 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 13 296 1.4E-67 T 06-07-2017 IPR005693 Virulence factor Mce protein CAK77_RS20815 5f3a9c603e998a3ab203934703e510f5 399 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 145 389 8.4E-58 T 06-07-2017 IPR024516 Mammalian cell entry, C-terminal CAK77_RS20815 5f3a9c603e998a3ab203934703e510f5 399 Pfam PF02470 MlaD protein 39 114 3.2E-10 T 06-07-2017 IPR003399 Mce/MlaD CAK77_RS16055 8ccc39d2069e0f4676a4d6c0f28cb19d 173 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 3 169 2.2E-42 T 06-07-2017 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 CAK77_RS16055 8ccc39d2069e0f4676a4d6c0f28cb19d 173 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 2 169 23.395 T 06-07-2017 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 CAK77_RS16055 8ccc39d2069e0f4676a4d6c0f28cb19d 173 Gene3D G3DSA:2.40.30.60 3 92 8.5E-25 T 06-07-2017 IPR002676 RimM protein GO:0006364 CAK77_RS16055 8ccc39d2069e0f4676a4d6c0f28cb19d 173 SUPERFAMILY SSF50447 3 92 2.22E-19 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain CAK77_RS16055 8ccc39d2069e0f4676a4d6c0f28cb19d 173 Pfam PF05239 PRC-barrel domain 96 170 3.1E-12 T 06-07-2017 IPR027275 PRC-barrel domain CAK77_RS16055 8ccc39d2069e0f4676a4d6c0f28cb19d 173 SUPERFAMILY SSF50346 99 169 4.32E-16 T 06-07-2017 IPR011033 PRC-barrel-like CAK77_RS16055 8ccc39d2069e0f4676a4d6c0f28cb19d 173 Gene3D G3DSA:2.30.30.240 99 169 1.4E-18 T 06-07-2017 CAK77_RS16055 8ccc39d2069e0f4676a4d6c0f28cb19d 173 Pfam PF01782 RimM N-terminal domain 4 87 1.4E-23 T 06-07-2017 IPR002676 RimM protein GO:0006364 CAK77_RS23895 3d28859af8298611f45798b21538b909 308 Gene3D G3DSA:3.40.50.1820 30 196 4.6E-29 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS23895 3d28859af8298611f45798b21538b909 308 Gene3D G3DSA:3.40.50.1820 235 306 4.6E-29 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS23895 3d28859af8298611f45798b21538b909 308 SUPERFAMILY SSF53474 20 306 1.47E-20 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS07230 e83bbcc092c054206bdd8db9572b6274 74 SUPERFAMILY SSF143800 1 67 2.83E-25 T 06-07-2017 CAK77_RS07230 e83bbcc092c054206bdd8db9572b6274 74 Hamap MF_00501 50S ribosomal protein L31 [rpmE]. 1 69 31.077 T 06-07-2017 IPR027491 Ribosomal protein L31 type A GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS07230 e83bbcc092c054206bdd8db9572b6274 74 Pfam PF01197 Ribosomal protein L31 1 66 1.3E-31 T 06-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS07230 e83bbcc092c054206bdd8db9572b6274 74 ProSitePatterns PS01143 Ribosomal protein L31 signature. 36 57 - T 06-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS07230 e83bbcc092c054206bdd8db9572b6274 74 PRINTS PR01249 Ribosomal protein L31 signature 32 47 5.1E-21 T 06-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS07230 e83bbcc092c054206bdd8db9572b6274 74 PRINTS PR01249 Ribosomal protein L31 signature 47 65 5.1E-21 T 06-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS07230 e83bbcc092c054206bdd8db9572b6274 74 PRINTS PR01249 Ribosomal protein L31 signature 2 19 5.1E-21 T 06-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS07230 e83bbcc092c054206bdd8db9572b6274 74 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 67 1.7E-32 T 06-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS03790 0a6a7eedd6c88ca6af83689edef0a827 101 Gene3D G3DSA:1.10.10.10 4 99 1.1E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS03790 0a6a7eedd6c88ca6af83689edef0a827 101 SMART SM00418 7 99 6.2E-6 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK77_RS03790 0a6a7eedd6c88ca6af83689edef0a827 101 SUPERFAMILY SSF46785 4 98 4.48E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS03790 0a6a7eedd6c88ca6af83689edef0a827 101 Pfam PF12840 Helix-turn-helix domain 7 78 4.4E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS04765 3137981f8e6b05c48adcb049f66797d5 198 SUPERFAMILY SSF46689 4 78 1.59E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS04765 3137981f8e6b05c48adcb049f66797d5 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 56 2.1E-4 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS04765 3137981f8e6b05c48adcb049f66797d5 198 Gene3D G3DSA:1.10.357.10 8 187 7.1E-23 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS03910 fc0c5caed6dba2de2214d93f6f81f7fb 359 Gene3D G3DSA:3.30.1330.10 26 172 7.4E-51 T 06-07-2017 IPR016188 PurM-like, N-terminal domain CAK77_RS03910 fc0c5caed6dba2de2214d93f6f81f7fb 359 Pfam PF02769 AIR synthase related protein, C-terminal domain 179 344 2.4E-34 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain CAK77_RS03910 fc0c5caed6dba2de2214d93f6f81f7fb 359 SUPERFAMILY SSF55326 11 172 1.92E-45 T 06-07-2017 CAK77_RS03910 fc0c5caed6dba2de2214d93f6f81f7fb 359 SUPERFAMILY SSF56042 175 342 5.98E-53 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain CAK77_RS03910 fc0c5caed6dba2de2214d93f6f81f7fb 359 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 10 352 41.0 T 06-07-2017 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CAK77_RS03910 fc0c5caed6dba2de2214d93f6f81f7fb 359 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 11 340 1.2E-136 T 06-07-2017 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CAK77_RS03910 fc0c5caed6dba2de2214d93f6f81f7fb 359 Pfam PF00586 AIR synthase related protein, N-terminal domain 63 167 1.7E-15 T 06-07-2017 IPR016188 PurM-like, N-terminal domain CAK77_RS03910 fc0c5caed6dba2de2214d93f6f81f7fb 359 Gene3D G3DSA:3.90.650.10 175 343 6.0E-63 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain CAK77_RS09875 473f3e789286346cd4985df3165674b9 313 Pfam PF00698 Acyl transferase domain 9 283 2.3E-16 T 06-07-2017 IPR014043 Acyl transferase CAK77_RS09875 473f3e789286346cd4985df3165674b9 313 SUPERFAMILY SSF52151 188 305 2.2E-44 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAK77_RS09875 473f3e789286346cd4985df3165674b9 313 SUPERFAMILY SSF52151 9 121 2.2E-44 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAK77_RS09875 473f3e789286346cd4985df3165674b9 313 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 9 302 1.6E-10 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain CAK77_RS09875 473f3e789286346cd4985df3165674b9 313 Gene3D G3DSA:3.30.70.250 125 194 8.6E-17 T 06-07-2017 CAK77_RS09875 473f3e789286346cd4985df3165674b9 313 SUPERFAMILY SSF55048 129 185 8.5E-8 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CAK77_RS09875 473f3e789286346cd4985df3165674b9 313 Gene3D G3DSA:3.40.366.10 8 121 7.2E-37 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAK77_RS09875 473f3e789286346cd4985df3165674b9 313 Gene3D G3DSA:3.40.366.10 195 297 7.2E-37 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAK77_RS19470 fb8c66b1f1b76458a0978c2082a1e628 55 SUPERFAMILY SSF57829 5 55 1.16E-18 T 06-07-2017 IPR011332 Zinc-binding ribosomal protein GO:0006412 CAK77_RS19470 fb8c66b1f1b76458a0978c2082a1e628 55 Pfam PF00471 Ribosomal protein L33 10 54 7.0E-22 T 06-07-2017 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS19470 fb8c66b1f1b76458a0978c2082a1e628 55 ProSitePatterns PS00582 Ribosomal protein L33 signature. 23 42 - T 06-07-2017 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS19470 fb8c66b1f1b76458a0978c2082a1e628 55 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 6 55 1.3E-19 T 06-07-2017 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS19470 fb8c66b1f1b76458a0978c2082a1e628 55 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 7 55 18.93 T 06-07-2017 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS10500 cd18f419747710609c2290bbf4be556b 306 Gene3D G3DSA:1.10.620.20 6 300 8.8E-102 T 06-07-2017 IPR012348 Ribonucleotide reductase-related GO:0016491|GO:0055114 Reactome: R-HSA-499943 CAK77_RS10500 cd18f419747710609c2290bbf4be556b 306 PIRSF PIRSF000346 1 306 1.4E-92 T 06-07-2017 IPR005067 Fatty acid desaturase, type 2 GO:0006631|GO:0045300|GO:0055114 CAK77_RS10500 cd18f419747710609c2290bbf4be556b 306 SUPERFAMILY SSF47240 5 296 2.21E-81 T 06-07-2017 IPR009078 Ferritin-like superfamily CAK77_RS10500 cd18f419747710609c2290bbf4be556b 306 Pfam PF03405 Fatty acid desaturase 8 301 1.0E-71 T 06-07-2017 IPR005067 Fatty acid desaturase, type 2 GO:0006631|GO:0045300|GO:0055114 CAK77_RS11280 204df3f3f10db2bcbdabbba6146c30a9 458 Pfam PF00756 Putative esterase 185 355 3.3E-15 T 06-07-2017 IPR000801 Putative esterase Reactome: R-HSA-156590 CAK77_RS11280 204df3f3f10db2bcbdabbba6146c30a9 458 SUPERFAMILY SSF53474 181 446 5.13E-28 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS11280 204df3f3f10db2bcbdabbba6146c30a9 458 Gene3D G3DSA:3.40.50.1820 153 449 3.8E-44 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS11400 0a986a4c269bb8e17579ddb3bd36c757 404 Hamap MF_00005 Argininosuccinate synthase [argG]. 6 401 51.443 T 06-07-2017 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CAK77_RS11400 0a986a4c269bb8e17579ddb3bd36c757 404 Gene3D G3DSA:3.90.1260.10 178 400 5.9E-80 T 06-07-2017 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CAK77_RS11400 0a986a4c269bb8e17579ddb3bd36c757 404 Pfam PF00764 Arginosuccinate synthase 10 395 1.4E-184 T 06-07-2017 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CAK77_RS11400 0a986a4c269bb8e17579ddb3bd36c757 404 Gene3D G3DSA:3.40.50.620 8 177 1.6E-55 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS11400 0a986a4c269bb8e17579ddb3bd36c757 404 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 12 20 - T 06-07-2017 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CAK77_RS11400 0a986a4c269bb8e17579ddb3bd36c757 404 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 121 132 - T 06-07-2017 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CAK77_RS11400 0a986a4c269bb8e17579ddb3bd36c757 404 SUPERFAMILY SSF69864 175 400 6.93E-85 T 06-07-2017 CAK77_RS11400 0a986a4c269bb8e17579ddb3bd36c757 404 TIGRFAM TIGR00032 argG: argininosuccinate synthase 8 397 8.2E-143 T 06-07-2017 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CAK77_RS11400 0a986a4c269bb8e17579ddb3bd36c757 404 SUPERFAMILY SSF52402 5 175 1.83E-42 T 06-07-2017 CAK77_RS06660 fb01ad22dba989bdae5d1babd49e2ab9 363 SUPERFAMILY SSF53383 4 361 2.5E-77 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK77_RS06660 fb01ad22dba989bdae5d1babd49e2ab9 363 TIGRFAM TIGR03539 DapC_actino: succinyldiaminopimelate transaminase 5 361 2.7E-177 T 06-07-2017 IPR019880 Succinyldiaminopimelate transaminase, DapC, actinobacteria CAK77_RS06660 fb01ad22dba989bdae5d1babd49e2ab9 363 Pfam PF00155 Aminotransferase class I and II 29 360 7.4E-44 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAK77_RS06660 fb01ad22dba989bdae5d1babd49e2ab9 363 Gene3D G3DSA:3.40.640.10 46 239 2.2E-40 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK77_RS06660 fb01ad22dba989bdae5d1babd49e2ab9 363 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 218 231 - T 06-07-2017 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CAK77_RS06660 fb01ad22dba989bdae5d1babd49e2ab9 363 Gene3D G3DSA:3.90.1150.10 240 361 3.6E-21 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK77_RS09900 449e977ea95ede161c20edee0f93155f 326 ProSitePatterns PS01174 Lipolytic enzymes "G-D-X-G" family, putative serine active site. 154 166 - T 06-07-2017 IPR033140 Lipase, GDXG, putative serine active site CAK77_RS09900 449e977ea95ede161c20edee0f93155f 326 Pfam PF07859 alpha/beta hydrolase fold 82 292 4.0E-69 T 06-07-2017 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CAK77_RS09900 449e977ea95ede161c20edee0f93155f 326 SUPERFAMILY SSF53474 53 312 9.2E-67 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS09900 449e977ea95ede161c20edee0f93155f 326 Gene3D G3DSA:3.40.50.1820 7 317 9.1E-91 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS13930 6194b907e22a363c861896941e8ce088 271 SUPERFAMILY SSF53223 5 104 1.44E-24 T 06-07-2017 CAK77_RS13930 6194b907e22a363c861896941e8ce088 271 Gene3D G3DSA:3.40.50.720 109 270 1.3E-36 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS13930 6194b907e22a363c861896941e8ce088 271 SUPERFAMILY SSF51735 105 270 9.43E-30 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS13930 6194b907e22a363c861896941e8ce088 271 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 10 92 2.2E-19 T 06-07-2017 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 CAK77_RS13930 6194b907e22a363c861896941e8ce088 271 Gene3D G3DSA:3.40.192.10 6 108 2.6E-32 T 06-07-2017 CAK77_RS13930 6194b907e22a363c861896941e8ce088 271 TIGRFAM TIGR01809 Shik-DH-AROM: shikimate-5-dehydrogenase 5 270 5.8E-75 T 06-07-2017 IPR010110 Shikimate dehydrogenase, AroM-type GO:0004764|GO:0005737|GO:0055114 KEGG: 00400+4.2.1.10+1.1.1.25+2.7.1.71+2.5.1.19+4.2.3.4|MetaCyc: PWY-6163|MetaCyc: PWY-6164|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAK77_RS13640 eec6694903537ec4013115323a035417 471 Gene3D G3DSA:2.30.170.30 2 54 2.4E-21 T 06-07-2017 CAK77_RS13640 eec6694903537ec4013115323a035417 471 PIRSF PIRSF018788 1 468 1.4E-225 T 06-07-2017 IPR010628 Ethanolamine ammonia lyase large subunit GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 CAK77_RS13640 eec6694903537ec4013115323a035417 471 Pfam PF06751 Ethanolamine ammonia lyase large subunit (EutB) 12 453 1.7E-207 T 06-07-2017 IPR010628 Ethanolamine ammonia lyase large subunit GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 CAK77_RS13640 eec6694903537ec4013115323a035417 471 Gene3D G3DSA:1.10.220.70 55 142 4.1E-36 T 06-07-2017 CAK77_RS13640 eec6694903537ec4013115323a035417 471 Gene3D G3DSA:3.20.20.70 146 455 2.0E-151 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK77_RS00200 821b052cdad197ac3f31e9d30e6b9f24 288 Gene3D G3DSA:3.20.20.370 40 232 8.8E-52 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAK77_RS00200 821b052cdad197ac3f31e9d30e6b9f24 288 Pfam PF01522 Polysaccharide deacetylase 47 156 8.7E-30 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAK77_RS00200 821b052cdad197ac3f31e9d30e6b9f24 288 SUPERFAMILY SSF88713 39 233 2.97E-53 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CAK77_RS19295 1f14945449a98eac8251e5a73abd970e 467 ProSitePatterns PS00218 Amino acid permeases signature. 48 78 - T 06-07-2017 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 CAK77_RS19295 1f14945449a98eac8251e5a73abd970e 467 PIRSF PIRSF006060 2 467 9.3E-61 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CAK77_RS19295 1f14945449a98eac8251e5a73abd970e 467 Pfam PF00324 Amino acid permease 24 456 5.8E-105 T 06-07-2017 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CAK77_RS23580 e980d20137d7d0d8feb90acf1c182021 163 Gene3D G3DSA:1.20.1260.10 16 158 1.6E-41 T 06-07-2017 IPR012347 Ferritin-related CAK77_RS23580 e980d20137d7d0d8feb90acf1c182021 163 PIRSF PIRSF005900 4 163 9.8E-37 T 06-07-2017 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CAK77_RS23580 e980d20137d7d0d8feb90acf1c182021 163 SUPERFAMILY SSF47240 15 158 9.02E-42 T 06-07-2017 IPR009078 Ferritin-like superfamily CAK77_RS23580 e980d20137d7d0d8feb90acf1c182021 163 ProSitePatterns PS00818 Dps protein family signature 1. 43 59 - T 06-07-2017 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 CAK77_RS23580 e980d20137d7d0d8feb90acf1c182021 163 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 67 83 7.1E-10 T 06-07-2017 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CAK77_RS23580 e980d20137d7d0d8feb90acf1c182021 163 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 138 156 7.1E-10 T 06-07-2017 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CAK77_RS23580 e980d20137d7d0d8feb90acf1c182021 163 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 43 59 7.1E-10 T 06-07-2017 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CAK77_RS23580 e980d20137d7d0d8feb90acf1c182021 163 Pfam PF00210 Ferritin-like domain 23 158 1.8E-19 T 06-07-2017 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 CAK77_RS01000 c268bb2d39cbf61dea40217d0c5efb42 272 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 6 267 1.0E-47 T 06-07-2017 IPR000150 Cof protein GO:0016787 CAK77_RS01000 c268bb2d39cbf61dea40217d0c5efb42 272 Gene3D G3DSA:3.40.50.1000 5 74 1.6E-50 T 06-07-2017 IPR023214 HAD-like domain CAK77_RS01000 c268bb2d39cbf61dea40217d0c5efb42 272 Gene3D G3DSA:3.40.50.1000 176 270 1.6E-50 T 06-07-2017 IPR023214 HAD-like domain CAK77_RS01000 c268bb2d39cbf61dea40217d0c5efb42 272 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 163 240 1.8E-12 T 06-07-2017 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CAK77_RS01000 c268bb2d39cbf61dea40217d0c5efb42 272 Pfam PF08282 haloacid dehalogenase-like hydrolase 7 267 2.4E-57 T 06-07-2017 IPR023214 HAD-like domain CAK77_RS01000 c268bb2d39cbf61dea40217d0c5efb42 272 SUPERFAMILY SSF56784 5 270 2.57E-61 T 06-07-2017 IPR023214 HAD-like domain CAK77_RS11610 74b363f2821f338762c156ee31cf2475 458 Gene3D G3DSA:3.90.1200.10 251 316 8.7E-8 T 06-07-2017 CAK77_RS11610 74b363f2821f338762c156ee31cf2475 458 Gene3D G3DSA:3.90.1200.10 155 203 5.8E-6 T 06-07-2017 CAK77_RS11610 74b363f2821f338762c156ee31cf2475 458 Pfam PF03109 ABC1 family 113 233 7.6E-32 T 06-07-2017 IPR004147 UbiB domain CAK77_RS11610 74b363f2821f338762c156ee31cf2475 458 SUPERFAMILY SSF56112 96 158 1.89E-28 T 06-07-2017 IPR011009 Protein kinase-like domain CAK77_RS11610 74b363f2821f338762c156ee31cf2475 458 SUPERFAMILY SSF56112 192 325 1.89E-28 T 06-07-2017 IPR011009 Protein kinase-like domain CAK77_RS16745 4f5f8b9ac71b04bf78dac8b6ae4218e1 1163 Gene3D G3DSA:3.40.50.720 770 1066 8.6E-30 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS16745 4f5f8b9ac71b04bf78dac8b6ae4218e1 1163 Pfam PF07993 Male sterility protein 773 1033 2.3E-51 T 06-07-2017 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 CAK77_RS16745 4f5f8b9ac71b04bf78dac8b6ae4218e1 1163 SUPERFAMILY SSF56801 75 627 2.09E-78 T 06-07-2017 CAK77_RS16745 4f5f8b9ac71b04bf78dac8b6ae4218e1 1163 Gene3D G3DSA:3.40.50.980 251 417 5.2E-20 T 06-07-2017 CAK77_RS16745 4f5f8b9ac71b04bf78dac8b6ae4218e1 1163 TIGRFAM TIGR01746 Thioester-redct: thioester reductase domain 770 1162 1.0E-89 T 06-07-2017 IPR010080 Thioester reductase-like domain CAK77_RS16745 4f5f8b9ac71b04bf78dac8b6ae4218e1 1163 SMART SM00823 Phosphopantetheine attachment site 649 721 9.0E-5 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAK77_RS16745 4f5f8b9ac71b04bf78dac8b6ae4218e1 1163 SUPERFAMILY SSF51735 770 1068 3.39E-30 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS16745 4f5f8b9ac71b04bf78dac8b6ae4218e1 1163 Pfam PF00550 Phosphopantetheine attachment site 651 717 1.2E-9 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS16745 4f5f8b9ac71b04bf78dac8b6ae4218e1 1163 Gene3D G3DSA:2.30.38.10 431 500 9.3E-13 T 06-07-2017 CAK77_RS16745 4f5f8b9ac71b04bf78dac8b6ae4218e1 1163 ProSitePatterns PS00455 Putative AMP-binding domain signature. 245 256 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK77_RS16745 4f5f8b9ac71b04bf78dac8b6ae4218e1 1163 Gene3D G3DSA:3.40.50.980 70 250 5.9E-19 T 06-07-2017 CAK77_RS16745 4f5f8b9ac71b04bf78dac8b6ae4218e1 1163 Pfam PF00501 AMP-binding enzyme 79 507 1.0E-57 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK77_RS16745 4f5f8b9ac71b04bf78dac8b6ae4218e1 1163 SUPERFAMILY SSF47336 643 728 1.28E-12 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS16745 4f5f8b9ac71b04bf78dac8b6ae4218e1 1163 Gene3D G3DSA:1.10.1200.10 641 723 4.7E-10 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS01470 1486deb893623b0cf5879fb0ffd5399b 324 SMART SM00829 10 321 1.7E-7 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAK77_RS01470 1486deb893623b0cf5879fb0ffd5399b 324 Gene3D G3DSA:3.90.180.10 1 146 1.2E-30 T 06-07-2017 IPR011032 GroES-like CAK77_RS01470 1486deb893623b0cf5879fb0ffd5399b 324 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 85 6.3E-5 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAK77_RS01470 1486deb893623b0cf5879fb0ffd5399b 324 Gene3D G3DSA:3.40.50.720 147 263 1.7E-23 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS01470 1486deb893623b0cf5879fb0ffd5399b 324 SUPERFAMILY SSF51735 114 290 4.37E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS01470 1486deb893623b0cf5879fb0ffd5399b 324 Pfam PF00107 Zinc-binding dehydrogenase 154 278 1.4E-18 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAK77_RS01470 1486deb893623b0cf5879fb0ffd5399b 324 SUPERFAMILY SSF50129 1 149 4.41E-26 T 06-07-2017 IPR011032 GroES-like CAK77_RS18745 4576be8530fa1e1973ec741a97ddd293 479 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 139 149 - T 06-07-2017 IPR022398 Peptidase S8, subtilisin, His-active site CAK77_RS18745 4576be8530fa1e1973ec741a97ddd293 479 SUPERFAMILY SSF52743 82 411 6.02E-62 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CAK77_RS18745 4576be8530fa1e1973ec741a97ddd293 479 Gene3D G3DSA:3.40.50.200 73 410 1.3E-69 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CAK77_RS18745 4576be8530fa1e1973ec741a97ddd293 479 Pfam PF00082 Subtilase family 98 402 9.7E-32 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CAK77_RS18745 4576be8530fa1e1973ec741a97ddd293 479 TIGRFAM TIGR03921 T7SS_mycosin: type VII secretion-associated serine protease mycosin 88 473 2.5E-123 T 06-07-2017 IPR023834 Type VII secretion system peptidase S8A, mycosin-1 CAK77_RS18745 4576be8530fa1e1973ec741a97ddd293 479 PRINTS PR00723 Subtilisin serine protease family (S8) signature 135 148 2.2E-12 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related CAK77_RS18745 4576be8530fa1e1973ec741a97ddd293 479 PRINTS PR00723 Subtilisin serine protease family (S8) signature 352 368 2.2E-12 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related CAK77_RS18745 4576be8530fa1e1973ec741a97ddd293 479 PRINTS PR00723 Subtilisin serine protease family (S8) signature 98 117 2.2E-12 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related CAK77_RS18745 4576be8530fa1e1973ec741a97ddd293 479 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 353 363 - T 06-07-2017 IPR023828 Peptidase S8, subtilisin, Ser-active site CAK77_RS21870 132f76ab9a3ab5c0469b3b0099c3c450 177 Pfam PF01575 MaoC like domain 37 150 1.1E-21 T 06-07-2017 IPR002539 MaoC-like domain CAK77_RS21870 132f76ab9a3ab5c0469b3b0099c3c450 177 Gene3D G3DSA:3.10.129.10 21 172 8.5E-42 T 06-07-2017 IPR029069 HotDog domain CAK77_RS21870 132f76ab9a3ab5c0469b3b0099c3c450 177 SUPERFAMILY SSF54637 21 172 2.01E-44 T 06-07-2017 IPR029069 HotDog domain CAK77_RS11545 ab903e7161576d64ed5a7123c5c62db7 223 Pfam PF02224 Cytidylate kinase 2 216 7.2E-78 T 06-07-2017 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 CAK77_RS11545 ab903e7161576d64ed5a7123c5c62db7 223 Gene3D G3DSA:3.40.50.300 1 216 4.6E-76 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS11545 ab903e7161576d64ed5a7123c5c62db7 223 Hamap MF_00238 Cytidylate kinase [cmk]. 1 219 31.49 T 06-07-2017 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 CAK77_RS11545 ab903e7161576d64ed5a7123c5c62db7 223 SUPERFAMILY SSF52540 1 217 9.53E-39 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS11545 ab903e7161576d64ed5a7123c5c62db7 223 TIGRFAM TIGR00017 cmk: cytidylate kinase 2 213 4.3E-70 T 06-07-2017 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 CAK77_RS14950 3242157e54f03d63ba7fb82dc184799f 150 Gene3D G3DSA:2.70.40.10 2 145 7.1E-54 T 06-07-2017 IPR029054 dUTPase-like CAK77_RS14950 3242157e54f03d63ba7fb82dc184799f 150 Hamap MF_00116 Deoxyuridine 5'-triphosphate nucleotidohydrolase [dut]. 2 146 29.448 T 06-07-2017 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7206|Reactome: R-HSA-500753 CAK77_RS14950 3242157e54f03d63ba7fb82dc184799f 150 TIGRFAM TIGR00576 dut: dUTP diphosphatase 2 145 3.2E-48 T 06-07-2017 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7206|Reactome: R-HSA-500753 CAK77_RS14950 3242157e54f03d63ba7fb82dc184799f 150 Pfam PF00692 dUTPase 10 145 3.4E-29 T 06-07-2017 IPR008180 Deoxyuridine triphosphate nucleotidohydrolase/Deoxycytidine triphosphate deaminase GO:0016787|GO:0046080 CAK77_RS14950 3242157e54f03d63ba7fb82dc184799f 150 SUPERFAMILY SSF51283 3 145 4.71E-44 T 06-07-2017 IPR029054 dUTPase-like CAK77_RS24395 07c350814a51341e3e46705db300f4de 462 Gene3D G3DSA:1.10.150.130 30 122 2.9E-6 T 06-07-2017 IPR023109 Integrase/recombinase, N-terminal CAK77_RS24395 07c350814a51341e3e46705db300f4de 462 Gene3D G3DSA:1.10.443.10 313 413 8.2E-23 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAK77_RS24395 07c350814a51341e3e46705db300f4de 462 Gene3D G3DSA:1.10.443.10 162 255 8.2E-23 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAK77_RS24395 07c350814a51341e3e46705db300f4de 462 SUPERFAMILY SSF56349 52 249 2.68E-17 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CAK77_RS24395 07c350814a51341e3e46705db300f4de 462 SUPERFAMILY SSF56349 308 412 2.68E-17 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CAK77_RS17380 07c350814a51341e3e46705db300f4de 462 Gene3D G3DSA:1.10.150.130 30 122 2.9E-6 T 06-07-2017 IPR023109 Integrase/recombinase, N-terminal CAK77_RS17380 07c350814a51341e3e46705db300f4de 462 Gene3D G3DSA:1.10.443.10 313 413 8.2E-23 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAK77_RS17380 07c350814a51341e3e46705db300f4de 462 Gene3D G3DSA:1.10.443.10 162 255 8.2E-23 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAK77_RS17380 07c350814a51341e3e46705db300f4de 462 SUPERFAMILY SSF56349 52 249 2.68E-17 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CAK77_RS17380 07c350814a51341e3e46705db300f4de 462 SUPERFAMILY SSF56349 308 412 2.68E-17 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CAK77_RS08755 ea90f7cb469e10c51e17343b6b27cde2 420 Gene3D G3DSA:3.40.190.10 155 347 4.8E-33 T 06-07-2017 CAK77_RS08755 ea90f7cb469e10c51e17343b6b27cde2 420 Pfam PF01547 Bacterial extracellular solute-binding protein 48 331 4.2E-34 T 06-07-2017 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 CAK77_RS08755 ea90f7cb469e10c51e17343b6b27cde2 420 Gene3D G3DSA:3.40.190.10 36 154 2.5E-15 T 06-07-2017 CAK77_RS08755 ea90f7cb469e10c51e17343b6b27cde2 420 SUPERFAMILY SSF53850 38 415 7.25E-58 T 06-07-2017 CAK77_RS20895 515f6964d0703a96e36db3720eeac925 396 SUPERFAMILY SSF53901 12 228 9.4E-25 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS20895 515f6964d0703a96e36db3720eeac925 396 Gene3D G3DSA:3.40.47.10 263 371 1.0E-6 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS20895 515f6964d0703a96e36db3720eeac925 396 SUPERFAMILY SSF53901 253 376 3.21E-16 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS20895 515f6964d0703a96e36db3720eeac925 396 PIRSF PIRSF000429 2 386 2.7E-20 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 CAK77_RS20895 515f6964d0703a96e36db3720eeac925 396 Gene3D G3DSA:3.40.47.10 193 224 6.1E-16 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS20895 515f6964d0703a96e36db3720eeac925 396 Gene3D G3DSA:3.40.47.10 17 117 6.1E-16 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS08985 90b851f72063c717d0edf38c7a0acab2 583 Gene3D G3DSA:3.20.20.140 325 521 4.5E-17 T 06-07-2017 CAK77_RS08985 90b851f72063c717d0edf38c7a0acab2 583 SUPERFAMILY SSF51338 20 98 1.26E-21 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK77_RS08985 90b851f72063c717d0edf38c7a0acab2 583 SUPERFAMILY SSF51338 537 581 1.26E-21 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK77_RS08985 90b851f72063c717d0edf38c7a0acab2 583 Gene3D G3DSA:2.30.40.10 27 97 3.6E-11 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK77_RS08985 90b851f72063c717d0edf38c7a0acab2 583 Pfam PF07969 Amidohydrolase family 86 578 2.7E-79 T 06-07-2017 IPR013108 Amidohydrolase 3 CAK77_RS08985 90b851f72063c717d0edf38c7a0acab2 583 SUPERFAMILY SSF51556 236 538 1.23E-23 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK77_RS08985 90b851f72063c717d0edf38c7a0acab2 583 SUPERFAMILY SSF51556 97 131 1.23E-23 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK77_RS08985 90b851f72063c717d0edf38c7a0acab2 583 Gene3D G3DSA:3.20.20.140 522 576 1.5E-9 T 06-07-2017 CAK77_RS10375 9ce4038da7a5564ab64356ee3d848218 128 Hamap MF_01394 NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic [ndhC]. 1 128 16.752 T 06-07-2017 IPR023043 NAD(P)H-quinone oxidoreductase subunit 3, bacterial/plastid GO:0016651|GO:0055114 CAK77_RS10375 9ce4038da7a5564ab64356ee3d848218 128 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 19 127 1.6E-32 T 06-07-2017 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS16720 eff225afe829e96de3706c467dd54c15 318 Gene3D G3DSA:3.40.50.620 1 178 5.1E-42 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS16720 eff225afe829e96de3706c467dd54c15 318 Pfam PF01012 Electron transfer flavoprotein domain 4 174 5.4E-33 T 06-07-2017 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CAK77_RS16720 eff225afe829e96de3706c467dd54c15 318 SUPERFAMILY SSF52467 191 312 6.07E-46 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAK77_RS16720 eff225afe829e96de3706c467dd54c15 318 PIRSF PIRSF000089 1 318 1.4E-103 T 06-07-2017 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 CAK77_RS16720 eff225afe829e96de3706c467dd54c15 318 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 194 276 6.9E-35 T 06-07-2017 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 CAK77_RS16720 eff225afe829e96de3706c467dd54c15 318 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 257 283 - T 06-07-2017 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 CAK77_RS16720 eff225afe829e96de3706c467dd54c15 318 SMART SM00893 4 193 5.3E-29 T 06-07-2017 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CAK77_RS16720 eff225afe829e96de3706c467dd54c15 318 Gene3D G3DSA:3.40.50.1220 191 314 3.2E-57 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAK77_RS16720 eff225afe829e96de3706c467dd54c15 318 SUPERFAMILY SSF52402 4 185 5.37E-41 T 06-07-2017 CAK77_RS04650 4393baa703f505a896067d42b7ad40db 141 SMART SM00347 28 126 1.6E-13 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK77_RS04650 4393baa703f505a896067d42b7ad40db 141 SMART SM00418 35 112 0.0065 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK77_RS04650 4393baa703f505a896067d42b7ad40db 141 SUPERFAMILY SSF46785 8 138 4.15E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS04650 4393baa703f505a896067d42b7ad40db 141 Gene3D G3DSA:1.10.10.10 5 138 1.3E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS04650 4393baa703f505a896067d42b7ad40db 141 PRINTS PR00598 Bacterial regulatory protein MarR family signature 87 103 7.1E-9 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK77_RS04650 4393baa703f505a896067d42b7ad40db 141 PRINTS PR00598 Bacterial regulatory protein MarR family signature 51 67 7.1E-9 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK77_RS04650 4393baa703f505a896067d42b7ad40db 141 PRINTS PR00598 Bacterial regulatory protein MarR family signature 116 136 7.1E-9 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK77_RS04650 4393baa703f505a896067d42b7ad40db 141 PRINTS PR00598 Bacterial regulatory protein MarR family signature 68 83 7.1E-9 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK77_RS04650 4393baa703f505a896067d42b7ad40db 141 Pfam PF01047 MarR family 40 92 5.2E-9 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK77_RS18000 973af547be1f538d86c70f4286e06f62 166 SUPERFAMILY SSF52255 4 163 1.03E-65 T 06-07-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CAK77_RS18000 973af547be1f538d86c70f4286e06f62 166 SMART SM01001 3 152 2.4E-93 T 06-07-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CAK77_RS18000 973af547be1f538d86c70f4286e06f62 166 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 5 159 4.9E-67 T 06-07-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CAK77_RS18000 973af547be1f538d86c70f4286e06f62 166 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 5 156 32.719 T 06-07-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CAK77_RS18000 973af547be1f538d86c70f4286e06f62 166 Gene3D G3DSA:3.40.50.7700 3 160 8.3E-73 T 06-07-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CAK77_RS18000 973af547be1f538d86c70f4286e06f62 166 PIRSF PIRSF001338 1 163 9.9E-69 T 06-07-2017 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 CAK77_RS18000 973af547be1f538d86c70f4286e06f62 166 Pfam PF00731 AIR carboxylase 4 149 6.4E-65 T 06-07-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CAK77_RS07605 d06afab540b45a1dbeae321edde40e8d 238 SUPERFAMILY SSF51445 54 196 3.37E-7 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily CAK77_RS07605 d06afab540b45a1dbeae321edde40e8d 238 Gene3D G3DSA:3.20.20.80 62 180 5.8E-7 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAK77_RS07605 d06afab540b45a1dbeae321edde40e8d 238 Pfam PF08924 Domain of unknown function (DUF1906) 49 174 3.7E-28 T 06-07-2017 IPR015020 Protein of unknown function DUF1906 CAK77_RS07605 d06afab540b45a1dbeae321edde40e8d 238 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 4 34 3.8E-4 T 06-07-2017 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal CAK77_RS07605 d06afab540b45a1dbeae321edde40e8d 238 Pfam PF10518 TAT (twin-arginine translocation) pathway signal sequence 4 27 2.6E-5 T 06-07-2017 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal CAK77_RS07895 c32a08d9da3b48a5eec45da14ceaae3b 529 Pfam PF00128 Alpha amylase, catalytic domain 36 381 1.1E-81 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CAK77_RS07895 c32a08d9da3b48a5eec45da14ceaae3b 529 Pfam PF11941 Domain of unknown function (DUF3459) 452 527 5.5E-5 T 06-07-2017 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) CAK77_RS07895 c32a08d9da3b48a5eec45da14ceaae3b 529 SMART SM00642 21 406 1.9E-119 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CAK77_RS07895 c32a08d9da3b48a5eec45da14ceaae3b 529 Gene3D G3DSA:3.20.20.80 11 112 5.9E-104 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAK77_RS07895 c32a08d9da3b48a5eec45da14ceaae3b 529 Gene3D G3DSA:3.20.20.80 191 467 5.9E-104 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAK77_RS07895 c32a08d9da3b48a5eec45da14ceaae3b 529 SUPERFAMILY SSF51445 12 466 8.86E-119 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily CAK77_RS07895 c32a08d9da3b48a5eec45da14ceaae3b 529 Gene3D G3DSA:3.90.400.10 113 190 1.9E-29 T 06-07-2017 CAK77_RS06810 a33af75bdb95ebd2769600c491c13545 214 Gene3D G3DSA:1.10.357.10 11 176 8.4E-22 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS06810 a33af75bdb95ebd2769600c491c13545 214 SUPERFAMILY SSF46689 8 75 2.39E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS06810 a33af75bdb95ebd2769600c491c13545 214 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 58 1.7E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS06810 a33af75bdb95ebd2769600c491c13545 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 3.2E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS06810 a33af75bdb95ebd2769600c491c13545 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 3.2E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS06705 d73b3ba36a4cb6fdf9540a550027825f 246 Gene3D G3DSA:1.10.10.60 197 240 5.3E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS06705 d73b3ba36a4cb6fdf9540a550027825f 246 SUPERFAMILY SSF46689 195 241 1.93E-8 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS06705 d73b3ba36a4cb6fdf9540a550027825f 246 Gene3D G3DSA:2.60.120.10 9 79 9.0E-12 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK77_RS06705 d73b3ba36a4cb6fdf9540a550027825f 246 SUPERFAMILY SSF51182 9 164 6.05E-14 T 06-07-2017 IPR011051 RmlC-like cupin domain CAK77_RS06705 d73b3ba36a4cb6fdf9540a550027825f 246 Pfam PF12833 Helix-turn-helix domain 167 241 1.9E-22 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK77_RS06705 d73b3ba36a4cb6fdf9540a550027825f 246 Gene3D G3DSA:1.10.10.60 138 196 4.9E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS06705 d73b3ba36a4cb6fdf9540a550027825f 246 Pfam PF02311 AraC-like ligand binding domain 16 131 3.0E-8 T 06-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CAK77_RS06705 d73b3ba36a4cb6fdf9540a550027825f 246 SMART SM00342 159 241 2.3E-26 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK77_RS03895 6af72af3bc9e9af32d21925b9025a2f0 207 SUPERFAMILY SSF46689 13 78 8.21E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS03895 6af72af3bc9e9af32d21925b9025a2f0 207 Gene3D G3DSA:1.10.357.10 8 204 7.9E-25 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS03895 6af72af3bc9e9af32d21925b9025a2f0 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 68 2.7E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS24370 fadc73c2c53f7a4e3e57b2748297731b 361 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 37 271 4.0E-57 T 06-07-2017 IPR028055 Membrane insertase YidC/Oxa1, C-terminal CAK77_RS24370 fadc73c2c53f7a4e3e57b2748297731b 361 Pfam PF02096 60Kd inner membrane protein 37 270 6.0E-49 T 06-07-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CAK77_RS04255 b58e610c75ff8b4e64123c9e064cc1af 158 SUPERFAMILY SSF50249 7 137 1.61E-30 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS04255 b58e610c75ff8b4e64123c9e064cc1af 158 Gene3D G3DSA:2.40.50.140 74 133 5.6E-4 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS04255 b58e610c75ff8b4e64123c9e064cc1af 158 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 70 133 6.7E-14 T 06-07-2017 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal CAK77_RS14080 a69bcd2169e01ca442d301e163a0f49e 558 Gene3D G3DSA:3.10.105.10 339 525 9.8E-17 T 06-07-2017 CAK77_RS14080 a69bcd2169e01ca442d301e163a0f49e 558 SUPERFAMILY SSF53850 229 554 2.17E-47 T 06-07-2017 CAK77_RS14080 a69bcd2169e01ca442d301e163a0f49e 558 SUPERFAMILY SSF53850 40 197 2.17E-47 T 06-07-2017 CAK77_RS14080 a69bcd2169e01ca442d301e163a0f49e 558 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 103 461 1.4E-18 T 06-07-2017 IPR000914 Solute-binding protein family 5 domain CAK77_RS14080 a69bcd2169e01ca442d301e163a0f49e 558 Gene3D G3DSA:3.90.76.10 102 237 1.8E-9 T 06-07-2017 CAK77_RS14080 a69bcd2169e01ca442d301e163a0f49e 558 Gene3D G3DSA:3.40.190.10 238 338 7.0E-14 T 06-07-2017 CAK77_RS00440 ed554f53e56011f4f14d37b5466a7082 294 Gene3D G3DSA:3.40.190.10 173 261 2.5E-19 T 06-07-2017 CAK77_RS00440 ed554f53e56011f4f14d37b5466a7082 294 Gene3D G3DSA:1.10.10.10 1 85 4.0E-31 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS00440 ed554f53e56011f4f14d37b5466a7082 294 Pfam PF03466 LysR substrate binding domain 88 289 1.7E-41 T 06-07-2017 IPR005119 LysR, substrate-binding CAK77_RS00440 ed554f53e56011f4f14d37b5466a7082 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 2.2E-24 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK77_RS00440 ed554f53e56011f4f14d37b5466a7082 294 SUPERFAMILY SSF53850 90 292 4.48E-41 T 06-07-2017 CAK77_RS00440 ed554f53e56011f4f14d37b5466a7082 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.1E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK77_RS00440 ed554f53e56011f4f14d37b5466a7082 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.1E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK77_RS00440 ed554f53e56011f4f14d37b5466a7082 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.1E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK77_RS00440 ed554f53e56011f4f14d37b5466a7082 294 Gene3D G3DSA:3.40.190.10 89 172 2.6E-20 T 06-07-2017 CAK77_RS00440 ed554f53e56011f4f14d37b5466a7082 294 SUPERFAMILY SSF46785 1 111 2.95E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS11445 fafbeea6587558b2ddf64a8dfbcf81b0 201 SUPERFAMILY SSF46689 7 70 2.1E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS11445 fafbeea6587558b2ddf64a8dfbcf81b0 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 4.4E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS11445 fafbeea6587558b2ddf64a8dfbcf81b0 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 4.4E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS11445 fafbeea6587558b2ddf64a8dfbcf81b0 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 65 1.5E-14 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS11445 fafbeea6587558b2ddf64a8dfbcf81b0 201 SUPERFAMILY SSF48498 84 194 4.15E-24 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS11445 fafbeea6587558b2ddf64a8dfbcf81b0 201 Gene3D G3DSA:1.10.10.60 5 65 1.3E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS11445 fafbeea6587558b2ddf64a8dfbcf81b0 201 Gene3D G3DSA:1.10.357.10 67 194 4.0E-35 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS02370 a270d0dddf8e125e7c4346b19d6cf524 549 Gene3D G3DSA:3.40.50.300 9 260 7.8E-72 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS02370 a270d0dddf8e125e7c4346b19d6cf524 549 Gene3D G3DSA:3.40.50.300 283 528 2.3E-78 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS02370 a270d0dddf8e125e7c4346b19d6cf524 549 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 507 542 0.022 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAK77_RS02370 a270d0dddf8e125e7c4346b19d6cf524 549 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 238 270 4.0E-5 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAK77_RS02370 a270d0dddf8e125e7c4346b19d6cf524 549 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK77_RS02370 a270d0dddf8e125e7c4346b19d6cf524 549 SUPERFAMILY SSF52540 10 258 2.09E-68 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS02370 a270d0dddf8e125e7c4346b19d6cf524 549 ProSitePatterns PS00211 ABC transporters family signature. 427 441 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK77_RS02370 a270d0dddf8e125e7c4346b19d6cf524 549 SMART SM00382 312 504 2.1E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS02370 a270d0dddf8e125e7c4346b19d6cf524 549 SMART SM00382 38 236 6.5E-19 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS02370 a270d0dddf8e125e7c4346b19d6cf524 549 SUPERFAMILY SSF52540 284 526 4.63E-72 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS02370 a270d0dddf8e125e7c4346b19d6cf524 549 Pfam PF00005 ABC transporter 30 186 7.0E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK77_RS02370 a270d0dddf8e125e7c4346b19d6cf524 549 Pfam PF00005 ABC transporter 304 455 3.3E-32 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK77_RS00605 5619d7dc3bd7e9a2e7b6cbf5ff095d8e 277 Pfam PF00106 short chain dehydrogenase 12 197 1.5E-54 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS00605 5619d7dc3bd7e9a2e7b6cbf5ff095d8e 277 Gene3D G3DSA:3.40.50.720 11 243 1.9E-71 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS00605 5619d7dc3bd7e9a2e7b6cbf5ff095d8e 277 SUPERFAMILY SSF51735 9 268 3.12E-70 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS00605 5619d7dc3bd7e9a2e7b6cbf5ff095d8e 277 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 10 193 6.7E-4 T 06-07-2017 CAK77_RS00605 5619d7dc3bd7e9a2e7b6cbf5ff095d8e 277 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK77_RS00605 5619d7dc3bd7e9a2e7b6cbf5ff095d8e 277 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 3.3E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS00605 5619d7dc3bd7e9a2e7b6cbf5ff095d8e 277 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 3.3E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS00605 5619d7dc3bd7e9a2e7b6cbf5ff095d8e 277 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 3.3E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS00605 5619d7dc3bd7e9a2e7b6cbf5ff095d8e 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 5.6E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS00605 5619d7dc3bd7e9a2e7b6cbf5ff095d8e 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 5.6E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS00605 5619d7dc3bd7e9a2e7b6cbf5ff095d8e 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 5.6E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS00605 5619d7dc3bd7e9a2e7b6cbf5ff095d8e 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 5.6E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS00605 5619d7dc3bd7e9a2e7b6cbf5ff095d8e 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 5.6E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS16100 36366c3b01b1c505ff7302fd4d965ff8 355 Gene3D G3DSA:3.20.20.140 59 317 2.2E-59 T 06-07-2017 CAK77_RS16100 36366c3b01b1c505ff7302fd4d965ff8 355 SUPERFAMILY SSF51556 45 320 4.26E-61 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK77_RS16100 36366c3b01b1c505ff7302fd4d965ff8 355 Gene3D G3DSA:2.30.40.10 17 58 5.9E-4 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK77_RS16100 36366c3b01b1c505ff7302fd4d965ff8 355 Pfam PF01979 Amidohydrolase family 42 329 2.3E-11 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAK77_RS16100 36366c3b01b1c505ff7302fd4d965ff8 355 Gene3D G3DSA:2.30.40.10 318 354 2.1E-4 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK77_RS06855 a6e210edce8904b05bea158498584fc7 320 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 10 240 1.4E-47 T 06-07-2017 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 CAK77_RS06855 a6e210edce8904b05bea158498584fc7 320 Gene3D G3DSA:3.20.20.60 6 251 4.8E-74 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAK77_RS06855 a6e210edce8904b05bea158498584fc7 320 SUPERFAMILY SSF51621 6 251 2.02E-62 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAK77_RS06855 a6e210edce8904b05bea158498584fc7 320 PIRSF PIRSF015582 3 317 6.2E-83 T 06-07-2017 IPR011206 Citrate lyase beta subunit-like CAK77_RS03975 5f0e7f9d8a95550c8388de161cafe944 277 SUPERFAMILY SSF52821 3 138 1.2E-36 T 06-07-2017 IPR001763 Rhodanese-like domain CAK77_RS03975 5f0e7f9d8a95550c8388de161cafe944 277 Gene3D G3DSA:3.40.250.10 2 138 1.6E-38 T 06-07-2017 IPR001763 Rhodanese-like domain CAK77_RS03975 5f0e7f9d8a95550c8388de161cafe944 277 Gene3D G3DSA:3.40.250.10 151 274 5.5E-36 T 06-07-2017 IPR001763 Rhodanese-like domain CAK77_RS03975 5f0e7f9d8a95550c8388de161cafe944 277 SUPERFAMILY SSF52821 149 275 8.64E-35 T 06-07-2017 IPR001763 Rhodanese-like domain CAK77_RS03975 5f0e7f9d8a95550c8388de161cafe944 277 Pfam PF00581 Rhodanese-like domain 149 266 1.5E-17 T 06-07-2017 IPR001763 Rhodanese-like domain CAK77_RS03975 5f0e7f9d8a95550c8388de161cafe944 277 Pfam PF00581 Rhodanese-like domain 9 118 3.1E-16 T 06-07-2017 IPR001763 Rhodanese-like domain CAK77_RS03975 5f0e7f9d8a95550c8388de161cafe944 277 SMART SM00450 8 122 6.2E-23 T 06-07-2017 IPR001763 Rhodanese-like domain CAK77_RS03975 5f0e7f9d8a95550c8388de161cafe944 277 SMART SM00450 144 271 5.3E-22 T 06-07-2017 IPR001763 Rhodanese-like domain CAK77_RS03975 5f0e7f9d8a95550c8388de161cafe944 277 ProSitePatterns PS00683 Rhodanese C-terminal signature. 255 265 - T 06-07-2017 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 CAK77_RS21075 5324acab9dafeacc96d7794550f4e6c8 296 SUPERFAMILY SSF52402 155 289 3.85E-16 T 06-07-2017 CAK77_RS21075 5324acab9dafeacc96d7794550f4e6c8 296 Pfam PF00582 Universal stress protein family 7 140 7.7E-11 T 06-07-2017 IPR006016 UspA GO:0006950 CAK77_RS21075 5324acab9dafeacc96d7794550f4e6c8 296 Pfam PF00582 Universal stress protein family 155 288 6.6E-11 T 06-07-2017 IPR006016 UspA GO:0006950 CAK77_RS21075 5324acab9dafeacc96d7794550f4e6c8 296 Gene3D G3DSA:3.40.50.620 149 288 4.6E-14 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS21075 5324acab9dafeacc96d7794550f4e6c8 296 SUPERFAMILY SSF52402 7 145 5.44E-18 T 06-07-2017 CAK77_RS21075 5324acab9dafeacc96d7794550f4e6c8 296 Gene3D G3DSA:3.40.50.620 6 142 2.4E-16 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS02785 a42c05c6a4a70d8da9a6b99633ae1849 350 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 14 275 8.5E-89 T 06-07-2017 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 CAK77_RS02785 a42c05c6a4a70d8da9a6b99633ae1849 350 Gene3D G3DSA:3.20.20.20 12 277 7.0E-100 T 06-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAK77_RS02785 a42c05c6a4a70d8da9a6b99633ae1849 350 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 48 61 - T 06-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAK77_RS02785 a42c05c6a4a70d8da9a6b99633ae1849 350 Pfam PF00809 Pterin binding enzyme 16 261 1.3E-79 T 06-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAK77_RS02785 a42c05c6a4a70d8da9a6b99633ae1849 350 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 14 29 - T 06-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAK77_RS02785 a42c05c6a4a70d8da9a6b99633ae1849 350 SUPERFAMILY SSF51717 12 276 1.44E-89 T 06-07-2017 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAK77_RS18855 49c4034a02432b8bcfea1b5ef584932e 331 Gene3D G3DSA:3.90.25.10 180 319 4.6E-44 T 06-07-2017 CAK77_RS18855 49c4034a02432b8bcfea1b5ef584932e 331 Gene3D G3DSA:3.40.50.720 1 179 1.0E-57 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS18855 49c4034a02432b8bcfea1b5ef584932e 331 SUPERFAMILY SSF51735 1 321 2.55E-89 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS18855 49c4034a02432b8bcfea1b5ef584932e 331 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 2 318 1.7E-139 T 06-07-2017 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688 CAK77_RS18855 49c4034a02432b8bcfea1b5ef584932e 331 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 294 7.3E-75 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS12880 5d02dae5310c9c320f4400a118c30efa 146 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 56 123 1.1E-11 T 06-07-2017 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal CAK77_RS12880 5d02dae5310c9c320f4400a118c30efa 146 SUPERFAMILY SSF50249 19 126 1.13E-17 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS12880 5d02dae5310c9c320f4400a118c30efa 146 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 20 53 1.1E-6 T 06-07-2017 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal CAK77_RS05685 2fd70594af4680ad97a778ae3a00bbaf 482 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 7 464 38.269 T 06-07-2017 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 CAK77_RS05685 2fd70594af4680ad97a778ae3a00bbaf 482 Gene3D G3DSA:3.90.550.10 8 258 2.9E-68 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK77_RS05685 2fd70594af4680ad97a778ae3a00bbaf 482 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 330 363 0.0027 T 06-07-2017 IPR001451 Hexapeptide repeat CAK77_RS05685 2fd70594af4680ad97a778ae3a00bbaf 482 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 278 311 1.7E-4 T 06-07-2017 IPR001451 Hexapeptide repeat CAK77_RS05685 2fd70594af4680ad97a778ae3a00bbaf 482 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 407 440 4.6E-6 T 06-07-2017 IPR001451 Hexapeptide repeat CAK77_RS05685 2fd70594af4680ad97a778ae3a00bbaf 482 Pfam PF12804 MobA-like NTP transferase domain 10 144 1.9E-19 T 06-07-2017 IPR025877 MobA-like NTP transferase CAK77_RS05685 2fd70594af4680ad97a778ae3a00bbaf 482 Gene3D G3DSA:2.160.10.10 346 471 1.7E-26 T 06-07-2017 CAK77_RS05685 2fd70594af4680ad97a778ae3a00bbaf 482 SUPERFAMILY SSF51161 262 472 3.63E-41 T 06-07-2017 IPR011004 Trimeric LpxA-like CAK77_RS05685 2fd70594af4680ad97a778ae3a00bbaf 482 Gene3D G3DSA:2.160.10.10 259 345 3.2E-16 T 06-07-2017 CAK77_RS05685 2fd70594af4680ad97a778ae3a00bbaf 482 SUPERFAMILY SSF53448 9 265 2.0E-56 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK77_RS05685 2fd70594af4680ad97a778ae3a00bbaf 482 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 9 466 5.1E-167 T 06-07-2017 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 CAK77_RS17500 122f921be917fd714ecdbc9b3fea3c4b 117 Pfam PF05423 Mycobacterium membrane protein 28 113 6.1E-8 T 06-07-2017 IPR008693 Transport accessory protein MmpS CAK77_RS09305 fb6babfd4c0b9670bc5beced2086866f 446 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 234 249 - T 06-07-2017 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 CAK77_RS09305 fb6babfd4c0b9670bc5beced2086866f 446 SUPERFAMILY SSF54368 7 104 2.49E-29 T 06-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CAK77_RS09305 fb6babfd4c0b9670bc5beced2086866f 446 Gene3D G3DSA:3.10.20.70 5 109 2.0E-37 T 06-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CAK77_RS09305 fb6babfd4c0b9670bc5beced2086866f 446 SMART SM01230 106 357 4.8E-123 T 06-07-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CAK77_RS09305 fb6babfd4c0b9670bc5beced2086866f 446 Gene3D G3DSA:3.30.590.10 110 433 7.7E-113 T 06-07-2017 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 CAK77_RS09305 fb6babfd4c0b9670bc5beced2086866f 446 SUPERFAMILY SSF55931 108 444 4.9E-114 T 06-07-2017 CAK77_RS09305 fb6babfd4c0b9670bc5beced2086866f 446 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 16 99 2.6E-26 T 06-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CAK77_RS09305 fb6babfd4c0b9670bc5beced2086866f 446 Pfam PF00120 Glutamine synthetase, catalytic domain 108 443 3.6E-126 T 06-07-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CAK77_RS17570 446f0db53d2cc6760e698818cb7e1c1a 94 Pfam PF02467 Transcription factor WhiB 15 63 6.3E-16 T 06-07-2017 IPR003482 Transcription factor WhiB CAK77_RS17570 446f0db53d2cc6760e698818cb7e1c1a 94 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 77 16.207 T 06-07-2017 IPR003482 Transcription factor WhiB CAK77_RS17570 446f0db53d2cc6760e698818cb7e1c1a 94 ProSitePatterns PS00354 HMG-I and HMG-Y DNA-binding domain (A+T-hook). 73 83 - T 06-07-2017 IPR000637 HMG-I/HMG-Y, DNA-binding, conserved site GO:0006355 CAK77_RS21260 f5cdf88ab501694c3e0246a321f18435 421 SUPERFAMILY SSF53383 54 420 3.9E-107 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK77_RS21260 f5cdf88ab501694c3e0246a321f18435 421 TIGRFAM TIGR01325 O_suc_HS_sulf: O-succinylhomoserine sulfhydrylase 35 420 2.8E-194 T 06-07-2017 IPR006234 O-succinylhomoserine sulfhydrylase GO:0071268 CAK77_RS21260 f5cdf88ab501694c3e0246a321f18435 421 PIRSF PIRSF001434 29 421 9.8E-114 T 06-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CAK77_RS21260 f5cdf88ab501694c3e0246a321f18435 421 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 36 420 2.1E-130 T 06-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CAK77_RS21260 f5cdf88ab501694c3e0246a321f18435 421 Hamap MF_02056 O-succinylhomoserine sulfhydrylase [metZ]. 36 421 52.016 T 06-07-2017 IPR006234 O-succinylhomoserine sulfhydrylase GO:0071268 CAK77_RS21260 f5cdf88ab501694c3e0246a321f18435 421 Gene3D G3DSA:3.40.640.10 47 282 6.0E-79 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK77_RS21260 f5cdf88ab501694c3e0246a321f18435 421 Gene3D G3DSA:3.90.1150.10 286 420 7.2E-47 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK77_RS24080 298ead07808a31502b15a3f81b34b9c2 151 SUPERFAMILY SSF55658 1 57 7.5E-17 T 06-07-2017 IPR009027 Ribosomal protein L9/RNase H1, N-terminal CAK77_RS24080 298ead07808a31502b15a3f81b34b9c2 151 Gene3D G3DSA:3.40.5.10 1 50 4.9E-21 T 06-07-2017 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS24080 298ead07808a31502b15a3f81b34b9c2 151 Gene3D G3DSA:3.10.430.100 62 150 1.4E-25 T 06-07-2017 IPR020069 Ribosomal protein L9, C-terminal CAK77_RS24080 298ead07808a31502b15a3f81b34b9c2 151 Pfam PF03948 Ribosomal protein L9, C-terminal domain 63 149 9.7E-24 T 06-07-2017 IPR020069 Ribosomal protein L9, C-terminal CAK77_RS24080 298ead07808a31502b15a3f81b34b9c2 151 SUPERFAMILY SSF55653 62 150 4.84E-22 T 06-07-2017 IPR020069 Ribosomal protein L9, C-terminal CAK77_RS24080 298ead07808a31502b15a3f81b34b9c2 151 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 150 24.206 T 06-07-2017 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS24080 298ead07808a31502b15a3f81b34b9c2 151 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 06-07-2017 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS24080 298ead07808a31502b15a3f81b34b9c2 151 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 45 6.7E-20 T 06-07-2017 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS24080 298ead07808a31502b15a3f81b34b9c2 151 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 150 7.4E-37 T 06-07-2017 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS22750 cf579b0e13e9f3c95f2ff8961f14587f 225 SUPERFAMILY SSF48008 84 216 6.8E-12 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAK77_RS22750 cf579b0e13e9f3c95f2ff8961f14587f 225 SMART SM00895 88 207 1.6E-6 T 06-07-2017 IPR011711 GntR, C-terminal CAK77_RS22750 cf579b0e13e9f3c95f2ff8961f14587f 225 Pfam PF00392 Bacterial regulatory proteins, gntR family 16 78 2.6E-15 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK77_RS22750 cf579b0e13e9f3c95f2ff8961f14587f 225 SUPERFAMILY SSF46785 12 82 1.65E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS22750 cf579b0e13e9f3c95f2ff8961f14587f 225 Gene3D G3DSA:1.20.120.530 81 217 1.1E-13 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAK77_RS22750 cf579b0e13e9f3c95f2ff8961f14587f 225 SMART SM00345 20 78 2.3E-12 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK77_RS22750 cf579b0e13e9f3c95f2ff8961f14587f 225 Gene3D G3DSA:1.10.10.10 5 79 2.0E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS22750 cf579b0e13e9f3c95f2ff8961f14587f 225 Pfam PF07729 FCD domain 88 197 3.3E-17 T 06-07-2017 IPR011711 GntR, C-terminal CAK77_RS17805 0bca6f8096424e19d014c8f336104d38 140 Gene3D G3DSA:3.10.129.10 11 135 5.6E-31 T 06-07-2017 IPR029069 HotDog domain CAK77_RS17805 0bca6f8096424e19d014c8f336104d38 140 Pfam PF03061 Thioesterase superfamily 46 122 8.2E-16 T 06-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 CAK77_RS17805 0bca6f8096424e19d014c8f336104d38 140 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 16 130 6.0E-22 T 06-07-2017 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-75105 CAK77_RS17805 0bca6f8096424e19d014c8f336104d38 140 SUPERFAMILY SSF54637 12 135 1.35E-25 T 06-07-2017 IPR029069 HotDog domain CAK77_RS11295 679f02e06585f0921fdf466e1495858f 204 SUPERFAMILY SSF55200 85 168 1.7E-29 T 06-07-2017 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 CAK77_RS11295 679f02e06585f0921fdf466e1495858f 204 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 84 167 2.6E-32 T 06-07-2017 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 CAK77_RS11295 679f02e06585f0921fdf466e1495858f 204 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 1 170 29.45 T 06-07-2017 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CAK77_RS11295 679f02e06585f0921fdf466e1495858f 204 ProSitePatterns PS00938 Initiation factor 3 signature. 58 71 - T 06-07-2017 IPR019813 Translation initiation factor 3, conserved site GO:0003743|GO:0006413 CAK77_RS11295 679f02e06585f0921fdf466e1495858f 204 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 7 168 9.7E-61 T 06-07-2017 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CAK77_RS11295 679f02e06585f0921fdf466e1495858f 204 SUPERFAMILY SSF54364 5 78 6.93E-29 T 06-07-2017 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CAK77_RS11295 679f02e06585f0921fdf466e1495858f 204 Gene3D G3DSA:3.10.20.80 3 78 5.2E-36 T 06-07-2017 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CAK77_RS11295 679f02e06585f0921fdf466e1495858f 204 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 7 75 1.8E-30 T 06-07-2017 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CAK77_RS11295 679f02e06585f0921fdf466e1495858f 204 Gene3D G3DSA:3.30.110.10 79 169 1.3E-35 T 06-07-2017 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 CAK77_RS24140 0e13e82aa9b81fde624426f8e63fe2dc 274 SUPERFAMILY SSF51679 20 270 1.56E-44 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS24140 0e13e82aa9b81fde624426f8e63fe2dc 274 TIGRFAM TIGR03619 F420_Rv2161c: probable F420-dependent oxidoreductase, Rv2161c family 20 249 3.6E-68 T 06-07-2017 IPR019921 Luciferase-like, F420-dependent oxidoreductase, Rv2161c, predicted CAK77_RS24140 0e13e82aa9b81fde624426f8e63fe2dc 274 Gene3D G3DSA:3.20.20.30 20 227 5.9E-47 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS24140 0e13e82aa9b81fde624426f8e63fe2dc 274 Pfam PF00296 Luciferase-like monooxygenase 20 219 5.4E-39 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS16295 8b4c841b912ad3144a373414ed664676 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 73 3.3E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS16295 8b4c841b912ad3144a373414ed664676 210 Gene3D G3DSA:1.10.357.10 19 205 7.6E-22 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS16295 8b4c841b912ad3144a373414ed664676 210 SUPERFAMILY SSF46689 20 97 6.16E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS19700 757638875d0b7a920188a1f03ed5b506 540 Gene3D G3DSA:3.40.50.970 323 530 7.3E-23 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK77_RS19700 757638875d0b7a920188a1f03ed5b506 540 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 397 512 6.9E-7 T 06-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CAK77_RS19700 757638875d0b7a920188a1f03ed5b506 540 SUPERFAMILY SSF52518 7 187 1.92E-30 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK77_RS19700 757638875d0b7a920188a1f03ed5b506 540 SUPERFAMILY SSF52518 353 529 1.26E-18 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK77_RS19700 757638875d0b7a920188a1f03ed5b506 540 TIGRFAM TIGR00173 menD: 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase 7 413 1.2E-100 T 06-07-2017 IPR004433 Menaquinone biosynthesis protein MenD GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 CAK77_RS19700 757638875d0b7a920188a1f03ed5b506 540 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 8 184 3.2E-27 T 06-07-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CAK77_RS19700 757638875d0b7a920188a1f03ed5b506 540 Hamap MF_01659 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase [menD]. 1 540 30.221 T 06-07-2017 IPR004433 Menaquinone biosynthesis protein MenD GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 CAK77_RS19700 757638875d0b7a920188a1f03ed5b506 540 PIRSF PIRSF004983 1 540 6.7E-143 T 06-07-2017 IPR004433 Menaquinone biosynthesis protein MenD GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 CAK77_RS19700 757638875d0b7a920188a1f03ed5b506 540 Gene3D G3DSA:3.40.50.970 7 187 3.6E-44 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK77_RS03760 bba6ba48336850a838a0a2455a3d7651 84 Pfam PF13490 Putative zinc-finger 12 46 3.8E-8 T 06-07-2017 IPR027383 Putative zinc-finger CAK77_RS22130 a2024ac636c0c5ea73502a4423f694d1 611 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 475 607 1.5E-31 T 06-07-2017 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain CAK77_RS22130 a2024ac636c0c5ea73502a4423f694d1 611 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 162 272 6.0E-19 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAK77_RS22130 a2024ac636c0c5ea73502a4423f694d1 611 Gene3D G3DSA:2.40.110.10 161 273 7.1E-26 T 06-07-2017 CAK77_RS22130 a2024ac636c0c5ea73502a4423f694d1 611 Gene3D G3DSA:1.20.140.10 274 468 4.7E-41 T 06-07-2017 CAK77_RS22130 a2024ac636c0c5ea73502a4423f694d1 611 SUPERFAMILY SSF56645 36 294 4.58E-44 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK77_RS22130 a2024ac636c0c5ea73502a4423f694d1 611 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 288 455 1.3E-14 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS22130 a2024ac636c0c5ea73502a4423f694d1 611 Pfam PF12418 Acyl-CoA dehydrogenase N terminal 3 34 9.4E-8 T 06-07-2017 IPR020953 Acyl-CoA dehydrogenase, N-terminal, bacteria CAK77_RS22130 a2024ac636c0c5ea73502a4423f694d1 611 SUPERFAMILY SSF47203 292 468 3.06E-31 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS22130 a2024ac636c0c5ea73502a4423f694d1 611 Gene3D G3DSA:1.10.540.10 36 148 1.5E-6 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS15840 8c9c8b58f78dd4b6a70259ad90f79733 245 Pfam PF01738 Dienelactone hydrolase family 17 238 9.8E-49 T 06-07-2017 IPR002925 Dienelactone hydrolase GO:0016787 CAK77_RS15840 8c9c8b58f78dd4b6a70259ad90f79733 245 SUPERFAMILY SSF53474 1 240 1.88E-41 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS15840 8c9c8b58f78dd4b6a70259ad90f79733 245 Gene3D G3DSA:3.40.50.1820 3 237 3.7E-48 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS09585 5a6349d93484582224bd5e6ce1e598c8 249 SUPERFAMILY SSF53335 16 197 8.52E-31 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS09585 5a6349d93484582224bd5e6ce1e598c8 249 Pfam PF13649 Methyltransferase domain 47 132 1.9E-13 T 06-07-2017 CAK77_RS09585 5a6349d93484582224bd5e6ce1e598c8 249 Gene3D G3DSA:3.40.50.150 14 187 7.7E-26 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS18965 a01e92868a6971dc21a9def8d49790cc 450 SUPERFAMILY SSF53223 9 199 2.69E-75 T 06-07-2017 CAK77_RS18965 a01e92868a6971dc21a9def8d49790cc 450 PIRSF PIRSF000185 25 450 2.8E-119 T 06-07-2017 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 CAK77_RS18965 a01e92868a6971dc21a9def8d49790cc 450 Gene3D G3DSA:1.10.285.10 13 69 6.9E-20 T 06-07-2017 CAK77_RS18965 a01e92868a6971dc21a9def8d49790cc 450 Gene3D G3DSA:1.10.285.10 375 449 1.2E-20 T 06-07-2017 CAK77_RS18965 a01e92868a6971dc21a9def8d49790cc 450 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 59 187 8.3E-51 T 06-07-2017 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 CAK77_RS18965 a01e92868a6971dc21a9def8d49790cc 450 SUPERFAMILY SSF51735 205 449 3.42E-75 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS18965 a01e92868a6971dc21a9def8d49790cc 450 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 124 137 - T 06-07-2017 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-70614 CAK77_RS18965 a01e92868a6971dc21a9def8d49790cc 450 SMART SM00839 207 448 4.7E-90 T 06-07-2017 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 CAK77_RS18965 a01e92868a6971dc21a9def8d49790cc 450 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 116 130 1.7E-30 T 06-07-2017 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 CAK77_RS18965 a01e92868a6971dc21a9def8d49790cc 450 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 238 258 1.7E-30 T 06-07-2017 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 CAK77_RS18965 a01e92868a6971dc21a9def8d49790cc 450 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 196 218 1.7E-30 T 06-07-2017 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 CAK77_RS18965 a01e92868a6971dc21a9def8d49790cc 450 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 374 385 1.7E-30 T 06-07-2017 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 CAK77_RS18965 a01e92868a6971dc21a9def8d49790cc 450 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 205 448 7.3E-86 T 06-07-2017 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 CAK77_RS18965 a01e92868a6971dc21a9def8d49790cc 450 Gene3D G3DSA:3.40.192.10 70 190 3.0E-62 T 06-07-2017 CAK77_RS18965 a01e92868a6971dc21a9def8d49790cc 450 Gene3D G3DSA:3.40.50.720 212 374 5.0E-62 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS17670 8623c38813025ef3ce977c86c3277bec 74 Pfam PF11305 Protein of unknown function (DUF3107) 1 72 4.4E-29 T 06-07-2017 IPR021456 Protein of unknown function DUF3107 CAK77_RS14885 97641b3d1b53bd125666db3d1bc27f4c 441 Pfam PF06965 Na+/H+ antiporter 1 21 406 6.1E-134 T 06-07-2017 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 CAK77_RS14885 97641b3d1b53bd125666db3d1bc27f4c 441 TIGRFAM TIGR00773 NhaA: Na+/H+ antiporter NhaA 23 403 2.3E-96 T 06-07-2017 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 CAK77_RS14885 97641b3d1b53bd125666db3d1bc27f4c 441 Gene3D G3DSA:1.20.1530.10 18 411 6.0E-136 T 06-07-2017 IPR023171 Na/H antiporter domain CAK77_RS14885 97641b3d1b53bd125666db3d1bc27f4c 441 Hamap MF_01844 Na(+)/H(+) antiporter NhaA [nhaA]. 19 415 21.01 T 06-07-2017 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 CAK77_RS21620 a893221e66a261e7c7b42c0ac9bcadce 189 Pfam PF00692 dUTPase 70 178 7.0E-11 T 06-07-2017 IPR008180 Deoxyuridine triphosphate nucleotidohydrolase/Deoxycytidine triphosphate deaminase GO:0016787|GO:0046080 CAK77_RS21620 a893221e66a261e7c7b42c0ac9bcadce 189 Gene3D G3DSA:2.70.40.10 2 184 5.7E-66 T 06-07-2017 IPR029054 dUTPase-like CAK77_RS21620 a893221e66a261e7c7b42c0ac9bcadce 189 SUPERFAMILY SSF51283 2 184 3.93E-56 T 06-07-2017 IPR029054 dUTPase-like CAK77_RS21620 a893221e66a261e7c7b42c0ac9bcadce 189 Hamap MF_00146 Deoxycytidine triphosphate deaminase [dcd]. 1 182 34.928 T 06-07-2017 IPR011962 Deoxycytidine triphosphate deaminase GO:0006229|GO:0008829 KEGG: 00240+3.5.4.13|MetaCyc: PWY-7187 CAK77_RS21620 a893221e66a261e7c7b42c0ac9bcadce 189 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 3 181 2.4E-65 T 06-07-2017 IPR011962 Deoxycytidine triphosphate deaminase GO:0006229|GO:0008829 KEGG: 00240+3.5.4.13|MetaCyc: PWY-7187 CAK77_RS21595 221ab00099179a567f39c12cf79a3ea7 813 Gene3D G3DSA:1.10.10.10 752 806 5.3E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS21595 221ab00099179a567f39c12cf79a3ea7 813 SMART SM00421 750 807 2.5E-21 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK77_RS21595 221ab00099179a567f39c12cf79a3ea7 813 Pfam PF00196 Bacterial regulatory proteins, luxR family 752 806 1.1E-14 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK77_RS21595 221ab00099179a567f39c12cf79a3ea7 813 ProSitePatterns PS00622 LuxR-type HTH domain signature. 767 794 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK77_RS21595 221ab00099179a567f39c12cf79a3ea7 813 SUPERFAMILY SSF46894 746 807 4.08E-16 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAK77_RS21595 221ab00099179a567f39c12cf79a3ea7 813 SUPERFAMILY SSF52540 10 146 7.71E-7 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS21595 221ab00099179a567f39c12cf79a3ea7 813 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 767 783 5.6E-9 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK77_RS21595 221ab00099179a567f39c12cf79a3ea7 813 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 753 767 5.6E-9 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK77_RS21595 221ab00099179a567f39c12cf79a3ea7 813 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 783 795 5.6E-9 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK77_RS02775 17460706da0d35bcadebbcc3ec0a4993 750 Gene3D G3DSA:1.10.8.60 341 406 4.8E-21 T 06-07-2017 CAK77_RS02775 17460706da0d35bcadebbcc3ec0a4993 750 SUPERFAMILY SSF140990 414 609 7.06E-67 T 06-07-2017 CAK77_RS02775 17460706da0d35bcadebbcc3ec0a4993 750 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 200 331 7.1E-46 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 CAK77_RS02775 17460706da0d35bcadebbcc3ec0a4993 750 SUPERFAMILY SSF52540 156 403 8.99E-71 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS02775 17460706da0d35bcadebbcc3ec0a4993 750 SMART SM00382 196 335 1.1E-25 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS02775 17460706da0d35bcadebbcc3ec0a4993 750 ProSitePatterns PS00674 AAA-protein family signature. 303 321 - T 06-07-2017 IPR003960 ATPase, AAA-type, conserved site GO:0005524 CAK77_RS02775 17460706da0d35bcadebbcc3ec0a4993 750 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 115 603 3.4E-227 T 06-07-2017 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 CAK77_RS02775 17460706da0d35bcadebbcc3ec0a4993 750 Gene3D G3DSA:3.40.50.300 156 340 7.0E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS02775 17460706da0d35bcadebbcc3ec0a4993 750 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 5 611 35.966 T 06-07-2017 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 CAK77_RS02775 17460706da0d35bcadebbcc3ec0a4993 750 Pfam PF01434 Peptidase family M41 394 602 4.3E-76 T 06-07-2017 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 CAK77_RS21780 e7ab9f4f86e7c86995c33e99c2739569 300 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 16 272 6.3E-79 T 06-07-2017 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 CAK77_RS21780 e7ab9f4f86e7c86995c33e99c2739569 300 Gene3D G3DSA:3.40.50.150 22 213 1.1E-16 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS21780 e7ab9f4f86e7c86995c33e99c2739569 300 Pfam PF04072 Leucine carboxyl methyltransferase 18 198 1.7E-54 T 06-07-2017 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 CAK77_RS21780 e7ab9f4f86e7c86995c33e99c2739569 300 SUPERFAMILY SSF53335 14 292 4.98E-67 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS19045 102f6ce667952e532da757fdbeb8d410 93 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 25.221 T 06-07-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK77_RS19045 102f6ce667952e532da757fdbeb8d410 93 Pfam PF00203 Ribosomal protein S19 3 83 6.6E-37 T 06-07-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK77_RS19045 102f6ce667952e532da757fdbeb8d410 93 Gene3D G3DSA:3.30.860.10 1 92 1.3E-41 T 06-07-2017 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK77_RS19045 102f6ce667952e532da757fdbeb8d410 93 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 3.2E-24 T 06-07-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK77_RS19045 102f6ce667952e532da757fdbeb8d410 93 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 3.2E-24 T 06-07-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK77_RS19045 102f6ce667952e532da757fdbeb8d410 93 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 3.2E-24 T 06-07-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK77_RS19045 102f6ce667952e532da757fdbeb8d410 93 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 92 7.4E-48 T 06-07-2017 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 CAK77_RS19045 102f6ce667952e532da757fdbeb8d410 93 PIRSF PIRSF002144 1 93 2.6E-32 T 06-07-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK77_RS19045 102f6ce667952e532da757fdbeb8d410 93 SUPERFAMILY SSF54570 3 83 4.97E-35 T 06-07-2017 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK77_RS19045 102f6ce667952e532da757fdbeb8d410 93 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 06-07-2017 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK77_RS03190 c29f3084de2d27c48a640df70694fe5c 316 SUPERFAMILY SSF54637 20 172 3.48E-19 T 06-07-2017 IPR029069 HotDog domain CAK77_RS03190 c29f3084de2d27c48a640df70694fe5c 316 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 235 295 1.4E-20 T 06-07-2017 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal CAK77_RS03190 c29f3084de2d27c48a640df70694fe5c 316 Gene3D G3DSA:3.10.129.10 22 164 1.0E-14 T 06-07-2017 IPR029069 HotDog domain CAK77_RS03190 c29f3084de2d27c48a640df70694fe5c 316 Pfam PF13452 N-terminal half of MaoC dehydratase 25 150 4.9E-18 T 06-07-2017 CAK77_RS03190 c29f3084de2d27c48a640df70694fe5c 316 SUPERFAMILY SSF50249 185 300 5.82E-22 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS15900 7f1492ecabd47c137d43ddcf56c62fc6 277 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 276 8.6E-74 T 06-07-2017 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CAK77_RS15900 7f1492ecabd47c137d43ddcf56c62fc6 277 Gene3D G3DSA:3.30.479.20 145 191 3.8E-19 T 06-07-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CAK77_RS15900 7f1492ecabd47c137d43ddcf56c62fc6 277 Gene3D G3DSA:3.30.479.20 240 275 3.8E-19 T 06-07-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CAK77_RS15900 7f1492ecabd47c137d43ddcf56c62fc6 277 ProSitePatterns PS01126 Elongation factor Ts signature 1. 12 27 - T 06-07-2017 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CAK77_RS15900 7f1492ecabd47c137d43ddcf56c62fc6 277 Hamap MF_00050 Elongation factor Ts [tsf]. 1 277 65.506 T 06-07-2017 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CAK77_RS15900 7f1492ecabd47c137d43ddcf56c62fc6 277 Gene3D G3DSA:3.30.479.20 58 141 1.2E-14 T 06-07-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CAK77_RS15900 7f1492ecabd47c137d43ddcf56c62fc6 277 Pfam PF00889 Elongation factor TS 67 276 3.1E-63 T 06-07-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CAK77_RS15900 7f1492ecabd47c137d43ddcf56c62fc6 277 Gene3D G3DSA:1.10.8.10 3 55 7.0E-23 T 06-07-2017 CAK77_RS15900 7f1492ecabd47c137d43ddcf56c62fc6 277 Gene3D G3DSA:1.10.286.20 196 239 4.3E-19 T 06-07-2017 CAK77_RS15900 7f1492ecabd47c137d43ddcf56c62fc6 277 ProSitePatterns PS01127 Elongation factor Ts signature 2. 71 81 - T 06-07-2017 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CAK77_RS15900 7f1492ecabd47c137d43ddcf56c62fc6 277 SUPERFAMILY SSF46934 5 55 1.38E-14 T 06-07-2017 IPR009060 UBA-like GO:0005515 CAK77_RS15900 7f1492ecabd47c137d43ddcf56c62fc6 277 SUPERFAMILY SSF54713 57 88 2.54E-39 T 06-07-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CAK77_RS15900 7f1492ecabd47c137d43ddcf56c62fc6 277 SUPERFAMILY SSF54713 179 275 2.54E-39 T 06-07-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CAK77_RS09120 16c8753c5a80e8f9d3da6ddee0a189a1 246 Pfam PF09203 MspA 50 244 6.2E-42 T 06-07-2017 IPR015286 Porin family, mycobacterial-type CAK77_RS09120 16c8753c5a80e8f9d3da6ddee0a189a1 246 Gene3D G3DSA:2.60.40.1650 184 246 5.0E-21 T 06-07-2017 CAK77_RS09120 16c8753c5a80e8f9d3da6ddee0a189a1 246 Gene3D G3DSA:2.60.40.1650 44 110 5.0E-21 T 06-07-2017 CAK77_RS03170 44c7566b815369a5661181dec557253b 386 Gene3D G3DSA:3.40.47.10 146 182 5.6E-46 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS03170 44c7566b815369a5661181dec557253b 386 Gene3D G3DSA:3.40.47.10 270 385 5.6E-46 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS03170 44c7566b815369a5661181dec557253b 386 SUPERFAMILY SSF53901 5 263 4.2E-61 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS03170 44c7566b815369a5661181dec557253b 386 PIRSF PIRSF000429 1 386 2.6E-116 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 CAK77_RS03170 44c7566b815369a5661181dec557253b 386 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 384 9.0E-112 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 CAK77_RS03170 44c7566b815369a5661181dec557253b 386 Pfam PF02803 Thiolase, C-terminal domain 264 385 1.5E-37 T 06-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CAK77_RS03170 44c7566b815369a5661181dec557253b 386 ProSitePatterns PS00737 Thiolases signature 2. 332 348 - T 06-07-2017 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CAK77_RS03170 44c7566b815369a5661181dec557253b 386 Pfam PF00108 Thiolase, N-terminal domain 5 255 3.6E-54 T 06-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CAK77_RS03170 44c7566b815369a5661181dec557253b 386 Gene3D G3DSA:3.40.47.10 5 124 8.4E-57 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS03170 44c7566b815369a5661181dec557253b 386 Gene3D G3DSA:3.40.47.10 183 269 8.4E-57 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS03170 44c7566b815369a5661181dec557253b 386 SUPERFAMILY SSF53901 264 385 8.23E-38 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS10925 17b8343fa44be3c8d6bf6d6bfe820528 465 SUPERFAMILY SSF53850 30 271 3.2E-32 T 06-07-2017 CAK77_RS10925 17b8343fa44be3c8d6bf6d6bfe820528 465 Pfam PF09084 NMT1/THI5 like 112 267 4.0E-12 T 06-07-2017 IPR015168 SsuA/THI5-like CAK77_RS10925 17b8343fa44be3c8d6bf6d6bfe820528 465 Gene3D G3DSA:3.40.190.10 134 256 9.2E-18 T 06-07-2017 CAK77_RS18915 b27c8290d621280e5814890082da2328 267 SUPERFAMILY SSF69318 84 190 3.27E-5 T 06-07-2017 CAK77_RS06130 fb9b44ed1ea38b9ff425a2dbc261c6f1 137 Pfam PF02627 Carboxymuconolactone decarboxylase family 36 109 5.6E-8 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CAK77_RS06130 fb9b44ed1ea38b9ff425a2dbc261c6f1 137 Gene3D G3DSA:1.20.1290.10 13 124 2.3E-9 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAK77_RS06130 fb9b44ed1ea38b9ff425a2dbc261c6f1 137 SUPERFAMILY SSF69118 13 111 2.82E-20 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAK77_RS19920 053d36969596b25cd9e3e2fecef9d5dc 203 Gene3D G3DSA:3.40.30.10 3 196 5.9E-38 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK77_RS19920 053d36969596b25cd9e3e2fecef9d5dc 203 SUPERFAMILY SSF52833 65 193 8.12E-29 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK77_RS19920 053d36969596b25cd9e3e2fecef9d5dc 203 Pfam PF00578 AhpC/TSA family 66 172 1.8E-20 T 06-07-2017 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CAK77_RS19920 053d36969596b25cd9e3e2fecef9d5dc 203 ProSitePatterns PS00194 Thioredoxin family active site. 79 97 - T 06-07-2017 IPR017937 Thioredoxin, conserved site GO:0045454 CAK77_RS02095 bceec0dc54406ff09f3f621986380907 186 SUPERFAMILY SSF46785 102 164 2.12E-5 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS08955 6508085b5f8f33f0e4d78cfbbd75c34a 272 SUPERFAMILY SSF89796 2 268 3.14E-57 T 06-07-2017 IPR023606 CoA-transferase family III domain CAK77_RS08955 6508085b5f8f33f0e4d78cfbbd75c34a 272 Gene3D G3DSA:3.40.50.10540 2 266 2.5E-55 T 06-07-2017 IPR023606 CoA-transferase family III domain CAK77_RS08955 6508085b5f8f33f0e4d78cfbbd75c34a 272 Pfam PF02515 CoA-transferase family III 4 261 2.2E-42 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 CAK77_RS12770 6d997297f377d4ac2604f664ce8d46fb 143 SUPERFAMILY SSF50475 10 139 2.5E-32 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS12770 6d997297f377d4ac2604f664ce8d46fb 143 Gene3D G3DSA:2.30.110.10 10 139 1.2E-24 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS12770 6d997297f377d4ac2604f664ce8d46fb 143 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 10 87 1.1E-11 T 06-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAK77_RS12770 6d997297f377d4ac2604f664ce8d46fb 143 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 10 139 2.3E-38 T 06-07-2017 IPR019920 F420-binding domain, putative CAK77_RS05680 7fcfa8940a3d82709211b0582230ff3a 328 Gene3D G3DSA:3.40.50.2020 169 297 4.0E-45 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like CAK77_RS05680 7fcfa8940a3d82709211b0582230ff3a 328 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 12 128 4.9E-44 T 06-07-2017 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CAK77_RS05680 7fcfa8940a3d82709211b0582230ff3a 328 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 13 325 3.6E-119 T 06-07-2017 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CAK77_RS05680 7fcfa8940a3d82709211b0582230ff3a 328 SMART SM01400 12 128 6.6E-69 T 06-07-2017 CAK77_RS05680 7fcfa8940a3d82709211b0582230ff3a 328 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 136 151 - T 06-07-2017 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 CAK77_RS05680 7fcfa8940a3d82709211b0582230ff3a 328 SUPERFAMILY SSF53271 77 316 1.12E-60 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like CAK77_RS05680 7fcfa8940a3d82709211b0582230ff3a 328 Pfam PF14572 Phosphoribosyl synthetase-associated domain 218 324 2.5E-20 T 06-07-2017 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CAK77_RS05680 7fcfa8940a3d82709211b0582230ff3a 328 Hamap MF_00583_B Ribose-phosphate pyrophosphokinase [prs]. 12 325 45.391 T 06-07-2017 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CAK77_RS05680 7fcfa8940a3d82709211b0582230ff3a 328 Gene3D G3DSA:3.40.50.2020 9 168 3.4E-70 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like CAK77_RS20680 6c0ded69e3e3eb76e84104ea72eec777 443 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 18 427 4.0E-134 T 06-07-2017 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 CAK77_RS20680 6c0ded69e3e3eb76e84104ea72eec777 443 PIRSF PIRSF000337 4 439 1.0E-136 T 06-07-2017 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 CAK77_RS20680 6c0ded69e3e3eb76e84104ea72eec777 443 SUPERFAMILY SSF51679 9 433 4.84E-110 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS20680 6c0ded69e3e3eb76e84104ea72eec777 443 Gene3D G3DSA:3.20.20.30 7 306 5.8E-115 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS20680 6c0ded69e3e3eb76e84104ea72eec777 443 Gene3D G3DSA:3.20.20.30 346 434 5.8E-115 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS20680 6c0ded69e3e3eb76e84104ea72eec777 443 Pfam PF00296 Luciferase-like monooxygenase 31 382 7.8E-58 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS17295 2b84addc4f045323ac0eac77fb765ea8 547 Gene3D G3DSA:3.40.50.970 353 539 1.1E-60 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK77_RS17295 2b84addc4f045323ac0eac77fb765ea8 547 Gene3D G3DSA:3.40.50.1220 184 331 1.2E-44 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAK77_RS17295 2b84addc4f045323ac0eac77fb765ea8 547 SUPERFAMILY SSF52518 2 173 5.89E-46 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK77_RS17295 2b84addc4f045323ac0eac77fb765ea8 547 Gene3D G3DSA:3.40.50.970 3 171 1.5E-57 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK77_RS17295 2b84addc4f045323ac0eac77fb765ea8 547 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 380 525 3.1E-42 T 06-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CAK77_RS17295 2b84addc4f045323ac0eac77fb765ea8 547 SUPERFAMILY SSF52467 185 337 3.89E-42 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAK77_RS17295 2b84addc4f045323ac0eac77fb765ea8 547 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 3 162 9.2E-49 T 06-07-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CAK77_RS17295 2b84addc4f045323ac0eac77fb765ea8 547 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 417 436 - T 06-07-2017 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 CAK77_RS17295 2b84addc4f045323ac0eac77fb765ea8 547 SUPERFAMILY SSF52518 357 537 2.28E-57 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK77_RS17295 2b84addc4f045323ac0eac77fb765ea8 547 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 189 323 8.1E-36 T 06-07-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CAK77_RS09505 94d6a6f1205deb6829a7e109374938b8 123 Gene3D G3DSA:2.60.300.12 19 113 6.5E-28 T 06-07-2017 IPR000361 FeS cluster biogenesis CAK77_RS09505 94d6a6f1205deb6829a7e109374938b8 123 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 19 123 1.1E-35 T 06-07-2017 IPR016092 FeS cluster insertion protein GO:0005198|GO:0016226|GO:0051536 CAK77_RS09505 94d6a6f1205deb6829a7e109374938b8 123 SUPERFAMILY SSF89360 19 113 2.35E-27 T 06-07-2017 IPR000361 FeS cluster biogenesis CAK77_RS09505 94d6a6f1205deb6829a7e109374938b8 123 Pfam PF01521 Iron-sulphur cluster biosynthesis 21 120 3.4E-19 T 06-07-2017 IPR000361 FeS cluster biogenesis CAK77_RS09505 94d6a6f1205deb6829a7e109374938b8 123 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 105 122 - T 06-07-2017 IPR017870 FeS cluster insertion, C-terminal, conserved site CAK77_RS22635 41dcfd009a4144995a8ef7e9efc316f8 214 SUPERFAMILY SSF53335 10 211 3.44E-40 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS22635 41dcfd009a4144995a8ef7e9efc316f8 214 Gene3D G3DSA:3.40.50.150 5 213 1.7E-56 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS22635 41dcfd009a4144995a8ef7e9efc316f8 214 Pfam PF01596 O-methyltransferase 26 168 1.8E-28 T 06-07-2017 IPR002935 O-methyltransferase, family 3 GO:0008171 CAK77_RS17760 b95554ebb8cc744ec2bfb1d83599f42c 251 SUPERFAMILY SSF143081 2 237 3.4E-62 T 06-07-2017 IPR003738 SOS response associated peptidase (SRAP) CAK77_RS17760 b95554ebb8cc744ec2bfb1d83599f42c 251 Pfam PF02586 SOS response associated peptidase (SRAP) 1 227 1.7E-62 T 06-07-2017 IPR003738 SOS response associated peptidase (SRAP) CAK77_RS17760 b95554ebb8cc744ec2bfb1d83599f42c 251 Gene3D G3DSA:3.90.1680.10 1 237 8.2E-67 T 06-07-2017 IPR003738 SOS response associated peptidase (SRAP) CAK77_RS18990 ac6525cb9a4a98c08c6a9838a604176e 187 Pfam PF00281 Ribosomal protein L5 31 87 1.6E-25 T 06-07-2017 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK77_RS18990 ac6525cb9a4a98c08c6a9838a604176e 187 Pfam PF00673 ribosomal L5P family C-terminus 91 184 7.2E-39 T 06-07-2017 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK77_RS18990 ac6525cb9a4a98c08c6a9838a604176e 187 Gene3D G3DSA:3.30.1440.10 8 185 8.9E-74 T 06-07-2017 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK77_RS18990 ac6525cb9a4a98c08c6a9838a604176e 187 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 8 186 42.797 T 06-07-2017 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS18990 ac6525cb9a4a98c08c6a9838a604176e 187 SUPERFAMILY SSF55282 10 185 3.3E-72 T 06-07-2017 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK77_RS18990 ac6525cb9a4a98c08c6a9838a604176e 187 PIRSF PIRSF002161 4 187 2.0E-62 T 06-07-2017 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK77_RS18075 7f719311c882a3b95bc49fc1983dd814 218 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 63 4.2E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS18075 7f719311c882a3b95bc49fc1983dd814 218 Gene3D G3DSA:1.10.357.10 4 200 2.4E-28 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS18075 7f719311c882a3b95bc49fc1983dd814 218 SUPERFAMILY SSF46689 14 86 1.35E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS09495 2cb019a1f4da2a1df098f46918bc5acd 224 Pfam PF11241 Protein of unknown function (DUF3043) 38 222 7.1E-59 T 06-07-2017 IPR021403 Protein of unknown function DUF3043 CAK77_RS01590 7e486a04f01b46869666d44fadfe079e 424 Gene3D G3DSA:3.30.390.10 6 126 1.6E-29 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAK77_RS01590 7e486a04f01b46869666d44fadfe079e 424 SUPERFAMILY SSF51604 141 418 5.37E-90 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAK77_RS01590 7e486a04f01b46869666d44fadfe079e 424 Pfam PF03952 Enolase, N-terminal domain 6 134 1.5E-34 T 06-07-2017 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAK77_RS01590 7e486a04f01b46869666d44fadfe079e 424 Pfam PF00113 Enolase, C-terminal TIM barrel domain 141 414 4.3E-78 T 06-07-2017 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAK77_RS01590 7e486a04f01b46869666d44fadfe079e 424 SUPERFAMILY SSF54826 6 136 2.65E-33 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAK77_RS01590 7e486a04f01b46869666d44fadfe079e 424 SMART SM01192 139 422 6.0E-129 T 06-07-2017 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAK77_RS01590 7e486a04f01b46869666d44fadfe079e 424 SMART SM01193 6 134 1.5E-49 T 06-07-2017 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAK77_RS01590 7e486a04f01b46869666d44fadfe079e 424 Gene3D G3DSA:3.20.20.120 128 416 4.5E-87 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAK77_RS01590 7e486a04f01b46869666d44fadfe079e 424 PIRSF PIRSF001400 2 420 5.3E-132 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAK77_RS01590 7e486a04f01b46869666d44fadfe079e 424 PRINTS PR00148 Enolase signature 107 123 4.5E-26 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAK77_RS01590 7e486a04f01b46869666d44fadfe079e 424 PRINTS PR00148 Enolase signature 334 348 4.5E-26 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAK77_RS01590 7e486a04f01b46869666d44fadfe079e 424 PRINTS PR00148 Enolase signature 363 380 4.5E-26 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAK77_RS01590 7e486a04f01b46869666d44fadfe079e 424 PRINTS PR00148 Enolase signature 161 174 4.5E-26 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAK77_RS01590 7e486a04f01b46869666d44fadfe079e 424 PRINTS PR00148 Enolase signature 311 322 4.5E-26 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAK77_RS01590 7e486a04f01b46869666d44fadfe079e 424 PRINTS PR00148 Enolase signature 39 53 4.5E-26 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAK77_RS01590 7e486a04f01b46869666d44fadfe079e 424 Hamap MF_00318 Enolase [eno]. 4 411 37.09 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAK77_RS17665 4674e0e6c161214a11abfa44b411055c 228 SUPERFAMILY SSF46689 31 115 1.1E-19 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS17665 4674e0e6c161214a11abfa44b411055c 228 Gene3D G3DSA:1.10.10.60 33 88 1.0E-20 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS17665 4674e0e6c161214a11abfa44b411055c 228 Pfam PF00440 Bacterial regulatory proteins, tetR family 46 89 4.7E-17 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS17665 4674e0e6c161214a11abfa44b411055c 228 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 56 3.0E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS17665 4674e0e6c161214a11abfa44b411055c 228 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 64 87 3.0E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS17665 4674e0e6c161214a11abfa44b411055c 228 SUPERFAMILY SSF48498 109 221 6.75E-25 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS17665 4674e0e6c161214a11abfa44b411055c 228 Gene3D G3DSA:1.10.357.10 89 220 3.5E-20 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS04625 e7ca63e8ec3f98cd1f895568c72fd621 458 Pfam PF10009 Uncharacterized protein conserved in bacteria (DUF2252) 55 446 1.1E-121 T 06-07-2017 IPR018721 Protein of unknown function DUF2252 CAK77_RS08675 4b4554a541781b55400ffccd5ce74903 472 Pfam PF03129 Anticodon binding domain 378 466 1.1E-21 T 06-07-2017 IPR004154 Anticodon-binding CAK77_RS08675 4b4554a541781b55400ffccd5ce74903 472 TIGRFAM TIGR00389 glyS_dimeric: glycine--tRNA ligase 12 247 2.2E-82 T 06-07-2017 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CAK77_RS08675 4b4554a541781b55400ffccd5ce74903 472 Gene3D G3DSA:3.30.930.10 134 373 3.0E-146 T 06-07-2017 CAK77_RS08675 4b4554a541781b55400ffccd5ce74903 472 Gene3D G3DSA:3.30.930.10 14 97 3.0E-146 T 06-07-2017 CAK77_RS08675 4b4554a541781b55400ffccd5ce74903 472 Gene3D G3DSA:3.40.50.800 374 469 4.2E-38 T 06-07-2017 IPR004154 Anticodon-binding CAK77_RS08675 4b4554a541781b55400ffccd5ce74903 472 SUPERFAMILY SSF55681 11 381 6.49E-122 T 06-07-2017 CAK77_RS08675 4b4554a541781b55400ffccd5ce74903 472 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 169 295 2.0E-7 T 06-07-2017 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK77_RS08675 4b4554a541781b55400ffccd5ce74903 472 SUPERFAMILY SSF52954 365 470 1.81E-33 T 06-07-2017 IPR004154 Anticodon-binding CAK77_RS08675 4b4554a541781b55400ffccd5ce74903 472 Hamap MF_00253_B Glycine--tRNA ligase [glyQS]. 9 470 49.689 T 06-07-2017 IPR022961 Glycine-tRNA ligase, bacterial GO:0004820 KEGG: 00970+6.1.1.14 CAK77_RS08675 4b4554a541781b55400ffccd5ce74903 472 PRINTS PR01043 Glycyl-tRNA synthetase signature 219 229 8.9E-56 T 06-07-2017 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CAK77_RS08675 4b4554a541781b55400ffccd5ce74903 472 PRINTS PR01043 Glycyl-tRNA synthetase signature 329 341 8.9E-56 T 06-07-2017 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CAK77_RS08675 4b4554a541781b55400ffccd5ce74903 472 PRINTS PR01043 Glycyl-tRNA synthetase signature 170 187 8.9E-56 T 06-07-2017 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CAK77_RS08675 4b4554a541781b55400ffccd5ce74903 472 PRINTS PR01043 Glycyl-tRNA synthetase signature 31 45 8.9E-56 T 06-07-2017 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CAK77_RS08675 4b4554a541781b55400ffccd5ce74903 472 PRINTS PR01043 Glycyl-tRNA synthetase signature 149 161 8.9E-56 T 06-07-2017 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CAK77_RS08675 4b4554a541781b55400ffccd5ce74903 472 PRINTS PR01043 Glycyl-tRNA synthetase signature 202 219 8.9E-56 T 06-07-2017 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CAK77_RS08675 4b4554a541781b55400ffccd5ce74903 472 PRINTS PR01043 Glycyl-tRNA synthetase signature 415 434 8.9E-56 T 06-07-2017 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CAK77_RS20705 fe3f15a08e4f8c6e73dc9a62b242fec6 675 Pfam PF00326 Prolyl oligopeptidase family 472 673 3.0E-48 T 06-07-2017 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 CAK77_RS20705 fe3f15a08e4f8c6e73dc9a62b242fec6 675 SUPERFAMILY SSF53474 418 673 1.33E-45 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS20705 fe3f15a08e4f8c6e73dc9a62b242fec6 675 Pfam PF02897 Prolyl oligopeptidase, N-terminal beta-propeller domain 7 225 1.4E-26 T 06-07-2017 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 CAK77_RS20705 fe3f15a08e4f8c6e73dc9a62b242fec6 675 SUPERFAMILY SSF50993 8 393 1.15E-51 T 06-07-2017 CAK77_RS20705 fe3f15a08e4f8c6e73dc9a62b242fec6 675 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 447 465 1.2E-44 T 06-07-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CAK77_RS20705 fe3f15a08e4f8c6e73dc9a62b242fec6 675 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 474 498 1.2E-44 T 06-07-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CAK77_RS20705 fe3f15a08e4f8c6e73dc9a62b242fec6 675 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 532 552 1.2E-44 T 06-07-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CAK77_RS20705 fe3f15a08e4f8c6e73dc9a62b242fec6 675 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 502 521 1.2E-44 T 06-07-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CAK77_RS20705 fe3f15a08e4f8c6e73dc9a62b242fec6 675 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 606 628 1.2E-44 T 06-07-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CAK77_RS20705 fe3f15a08e4f8c6e73dc9a62b242fec6 675 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 587 602 1.2E-44 T 06-07-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CAK77_RS20705 fe3f15a08e4f8c6e73dc9a62b242fec6 675 Gene3D G3DSA:3.40.50.1820 345 673 1.4E-86 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS06975 b5468a0b3e814793937535bae1c13e38 1234 SMART SM00861 880 1079 6.7E-43 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain CAK77_RS06975 b5468a0b3e814793937535bae1c13e38 1234 SUPERFAMILY SSF52518 867 1086 9.62E-43 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK77_RS06975 b5468a0b3e814793937535bae1c13e38 1234 SUPERFAMILY SSF52777 93 339 1.96E-52 T 06-07-2017 CAK77_RS06975 b5468a0b3e814793937535bae1c13e38 1234 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 106 339 2.1E-54 T 06-07-2017 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CAK77_RS06975 b5468a0b3e814793937535bae1c13e38 1234 SUPERFAMILY SSF52518 406 816 1.45E-84 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK77_RS06975 b5468a0b3e814793937535bae1c13e38 1234 PIRSF PIRSF000157 1 1231 0.0 T 06-07-2017 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 CAK77_RS06975 b5468a0b3e814793937535bae1c13e38 1234 Pfam PF00676 Dehydrogenase E1 component 493 813 5.0E-56 T 06-07-2017 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 CAK77_RS06975 b5468a0b3e814793937535bae1c13e38 1234 Pfam PF16870 2-oxoglutarate dehydrogenase C-terminal 1084 1229 3.0E-41 T 06-07-2017 IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 CAK77_RS06975 b5468a0b3e814793937535bae1c13e38 1234 Pfam PF02779 Transketolase, pyrimidine binding domain 879 1079 1.2E-52 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain CAK77_RS06975 b5468a0b3e814793937535bae1c13e38 1234 Gene3D G3DSA:3.30.559.10 93 339 8.1E-49 T 06-07-2017 IPR023213 Chloramphenicol acetyltransferase-like domain Reactome: R-HSA-389661 CAK77_RS06975 b5468a0b3e814793937535bae1c13e38 1234 Pfam PF16078 2-oxoglutarate dehydrogenase N-terminus 8 43 2.5E-11 T 06-07-2017 IPR032106 2-oxoglutarate dehydrogenase E1 component, N-terminal domain KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 CAK77_RS06975 b5468a0b3e814793937535bae1c13e38 1234 Gene3D G3DSA:3.40.50.970 949 1090 6.5E-17 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK77_RS06975 b5468a0b3e814793937535bae1c13e38 1234 TIGRFAM TIGR00239 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component 360 1228 0.0 T 06-07-2017 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 CAK77_RS06975 b5468a0b3e814793937535bae1c13e38 1234 Gene3D G3DSA:3.40.50.970 447 831 8.8E-77 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK77_RS06465 946b03aaefae8dc5bb962ba52c1cb6e6 164 Pfam PF08534 Redoxin 20 160 5.1E-23 T 06-07-2017 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 CAK77_RS06465 946b03aaefae8dc5bb962ba52c1cb6e6 164 Hamap MF_00269 Probable thiol peroxidase [tpx]. 3 164 36.482 T 06-07-2017 IPR002065 Putative thiol peroxidase Tpx GO:0008379|GO:0016209|GO:0055114 CAK77_RS06465 946b03aaefae8dc5bb962ba52c1cb6e6 164 SUPERFAMILY SSF52833 1 160 4.54E-41 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK77_RS06465 946b03aaefae8dc5bb962ba52c1cb6e6 164 Gene3D G3DSA:3.40.30.10 2 163 1.7E-46 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK77_RS06465 946b03aaefae8dc5bb962ba52c1cb6e6 164 ProSitePatterns PS01265 Tpx family signature. 82 93 - T 06-07-2017 IPR018219 Thiol peroxidase conserved site GO:0016684|GO:0055114 CAK77_RS02675 7a689d2e082d7489ed19415320e806ab 431 Pfam PF00266 Aminotransferase class-V 36 393 4.0E-75 T 06-07-2017 IPR000192 Aminotransferase class V domain CAK77_RS02675 7a689d2e082d7489ed19415320e806ab 431 SUPERFAMILY SSF53383 32 402 4.38E-74 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK77_RS02675 7a689d2e082d7489ed19415320e806ab 431 Gene3D G3DSA:3.40.640.10 48 279 1.0E-59 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK77_RS02675 7a689d2e082d7489ed19415320e806ab 431 Gene3D G3DSA:3.90.1150.10 280 399 2.4E-14 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK77_RS02675 7a689d2e082d7489ed19415320e806ab 431 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 213 232 - T 06-07-2017 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site CAK77_RS00660 928fb84e068db523b8dafca3aebe8673 276 Gene3D G3DSA:3.40.50.720 4 273 8.9E-76 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS00660 928fb84e068db523b8dafca3aebe8673 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 193 7.5E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS00660 928fb84e068db523b8dafca3aebe8673 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 164 7.5E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS00660 928fb84e068db523b8dafca3aebe8673 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 237 257 7.5E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS00660 928fb84e068db523b8dafca3aebe8673 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 100 111 7.5E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS00660 928fb84e068db523b8dafca3aebe8673 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 195 212 7.5E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS00660 928fb84e068db523b8dafca3aebe8673 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 7.5E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS00660 928fb84e068db523b8dafca3aebe8673 276 SUPERFAMILY SSF51735 11 274 3.01E-69 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS00660 928fb84e068db523b8dafca3aebe8673 276 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 273 4.5E-50 T 06-07-2017 CAK77_RS00660 928fb84e068db523b8dafca3aebe8673 276 TIGRFAM TIGR03971 SDR_subfam_1: SDR family mycofactocin-dependent oxidoreductase 9 275 2.9E-104 T 06-07-2017 IPR023985 Mycofactocin-dependent oxidoreductase CAK77_RS00660 928fb84e068db523b8dafca3aebe8673 276 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 161 189 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK77_RS00660 928fb84e068db523b8dafca3aebe8673 276 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 174 193 5.3E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS00660 928fb84e068db523b8dafca3aebe8673 276 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 100 111 5.3E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS00660 928fb84e068db523b8dafca3aebe8673 276 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 162 5.3E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS14660 c7e6cb497df6a6cc4e52e71811f9636a 423 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 105 291 2.6E-7 T 06-07-2017 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 CAK77_RS14660 c7e6cb497df6a6cc4e52e71811f9636a 423 Gene3D G3DSA:3.20.20.60 115 294 1.9E-14 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAK77_RS14660 c7e6cb497df6a6cc4e52e71811f9636a 423 SUPERFAMILY SSF51621 89 333 1.65E-17 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAK77_RS12945 870803e1eba1d46a04832e60efb0357d 342 PIRSF PIRSF000267 1 338 3.4E-111 T 06-07-2017 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 CAK77_RS12945 870803e1eba1d46a04832e60efb0357d 342 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 5 218 2.0E-69 T 06-07-2017 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 CAK77_RS12945 870803e1eba1d46a04832e60efb0357d 342 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 6 324 5.0E-108 T 06-07-2017 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 CAK77_RS02205 9e93ba3c216034748445ceccb4e52044 157 Pfam PF12728 Helix-turn-helix domain 6 51 4.4E-13 T 06-07-2017 CAK77_RS02205 9e93ba3c216034748445ceccb4e52044 157 SUPERFAMILY SSF46955 6 60 1.04E-8 T 06-07-2017 IPR009061 Putative DNA-binding domain CAK77_RS02205 9e93ba3c216034748445ceccb4e52044 157 Gene3D G3DSA:1.10.1660.10 7 51 9.2E-4 T 06-07-2017 CAK77_RS02205 9e93ba3c216034748445ceccb4e52044 157 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 6 51 7.0E-16 T 06-07-2017 IPR010093 SinI-like, DNA-binding domain GO:0003677 CAK77_RS16475 62f01c3a495bb478e50c84fdf6c3c3cd 467 SUPERFAMILY SSF56112 202 313 1.12E-20 T 06-07-2017 IPR011009 Protein kinase-like domain CAK77_RS16475 62f01c3a495bb478e50c84fdf6c3c3cd 467 SUPERFAMILY SSF56112 96 159 1.12E-20 T 06-07-2017 IPR011009 Protein kinase-like domain CAK77_RS16475 62f01c3a495bb478e50c84fdf6c3c3cd 467 Pfam PF03109 ABC1 family 113 234 7.3E-32 T 06-07-2017 IPR004147 UbiB domain CAK77_RS03920 e24e7688f4eac896d47cf1f08a275cf3 364 Pfam PF01571 Aminomethyltransferase folate-binding domain 18 228 8.8E-20 T 06-07-2017 IPR006222 Glycine cleavage T-protein-like, N-terminal CAK77_RS03920 e24e7688f4eac896d47cf1f08a275cf3 364 PIRSF PIRSF006487 13 319 5.5E-14 T 06-07-2017 IPR028896 Aminomethyltransferase/Dimethylsulfonioproprionate demethylase DmdA KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 CAK77_RS03920 e24e7688f4eac896d47cf1f08a275cf3 364 TIGRFAM TIGR03317 ygfZ_signature: folate-binding protein YgfZ 200 269 8.5E-19 T 06-07-2017 IPR017703 YgfZ/GcvT conserved site CAK77_RS03920 e24e7688f4eac896d47cf1f08a275cf3 364 SUPERFAMILY SSF103025 16 259 2.35E-51 T 06-07-2017 CAK77_RS03920 e24e7688f4eac896d47cf1f08a275cf3 364 Gene3D G3DSA:3.30.70.1400 41 126 1.6E-5 T 06-07-2017 CAK77_RS03920 e24e7688f4eac896d47cf1f08a275cf3 364 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 243 312 5.0E-7 T 06-07-2017 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CAK77_RS08600 060e9d5740da677a27d1e36ec40e8797 168 Gene3D G3DSA:3.30.530.20 3 146 2.2E-15 T 06-07-2017 IPR023393 START-like domain CAK77_RS08600 060e9d5740da677a27d1e36ec40e8797 168 SUPERFAMILY SSF55961 9 145 2.75E-15 T 06-07-2017 CAK77_RS01865 9ecea5e23b9a800d48fedf2f82b10c86 427 Pfam PF12867 DinB superfamily 10 140 1.7E-20 T 06-07-2017 IPR024775 DinB-like domain CAK77_RS01865 9ecea5e23b9a800d48fedf2f82b10c86 427 Hamap MF_02035 Hercynine oxygenase [egtB]. 1 427 50.42 T 06-07-2017 IPR032890 Hercynine oxygenase, Actinobacteria GO:0016491|GO:0052699 KEGG: 00340+1.14.99.50|MetaCyc: PWY-7255 CAK77_RS01865 9ecea5e23b9a800d48fedf2f82b10c86 427 Pfam PF03781 Sulfatase-modifying factor enzyme 1 169 424 3.1E-57 T 06-07-2017 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 CAK77_RS01865 9ecea5e23b9a800d48fedf2f82b10c86 427 Gene3D G3DSA:3.90.1580.10 166 427 1.5E-71 T 06-07-2017 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 CAK77_RS01865 9ecea5e23b9a800d48fedf2f82b10c86 427 SUPERFAMILY SSF56436 171 426 2.07E-71 T 06-07-2017 IPR016187 C-type lectin fold CAK77_RS01865 9ecea5e23b9a800d48fedf2f82b10c86 427 TIGRFAM TIGR03440 egtB_TIGR03440: ergothioneine biosynthesis protein EgtB 6 424 3.7E-121 T 06-07-2017 IPR017806 Ergothioneine biosynthesis protein EgtB GO:0052699 KEGG: 00340+1.14.99.50|MetaCyc: PWY-7255 CAK77_RS01865 9ecea5e23b9a800d48fedf2f82b10c86 427 SUPERFAMILY SSF109854 3 136 1.83E-13 T 06-07-2017 CAK77_RS23980 09581b94a9a77f1e4beea46c320929e8 308 Pfam PF02558 Ketopantoate reductase PanE/ApbA 17 160 1.5E-27 T 06-07-2017 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 CAK77_RS23980 09581b94a9a77f1e4beea46c320929e8 308 Gene3D G3DSA:1.10.1040.10 190 301 1.0E-25 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAK77_RS23980 09581b94a9a77f1e4beea46c320929e8 308 SUPERFAMILY SSF51735 17 124 1.25E-10 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS23980 09581b94a9a77f1e4beea46c320929e8 308 Gene3D G3DSA:3.40.50.720 16 189 1.8E-31 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS23980 09581b94a9a77f1e4beea46c320929e8 308 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 17 302 3.3E-46 T 06-07-2017 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0015940|GO:0016491|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 CAK77_RS23980 09581b94a9a77f1e4beea46c320929e8 308 SUPERFAMILY SSF48179 182 302 1.12E-24 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAK77_RS23980 09581b94a9a77f1e4beea46c320929e8 308 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 182 301 2.8E-21 T 06-07-2017 IPR013752 Ketopantoate reductase, C-terminal domain GO:0016491|GO:0050661|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 CAK77_RS03470 1f38ea5e355a35324901e188ac3aaadf 345 SUPERFAMILY SSF51905 8 52 2.59E-11 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS03470 1f38ea5e355a35324901e188ac3aaadf 345 SUPERFAMILY SSF51905 90 190 2.59E-11 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS03470 1f38ea5e355a35324901e188ac3aaadf 345 SUPERFAMILY SSF51905 236 275 2.59E-11 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS03470 1f38ea5e355a35324901e188ac3aaadf 345 Gene3D G3DSA:3.50.50.60 8 213 2.4E-8 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS03470 1f38ea5e355a35324901e188ac3aaadf 345 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 1.8E-5 T 06-07-2017 CAK77_RS03470 1f38ea5e355a35324901e188ac3aaadf 345 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 287 309 1.8E-5 T 06-07-2017 CAK77_RS03470 1f38ea5e355a35324901e188ac3aaadf 345 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 137 155 1.8E-5 T 06-07-2017 CAK77_RS18175 dfa9dfa635559a690cae20e4b5d98067 520 SUPERFAMILY SSF53720 42 508 7.2E-135 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAK77_RS18175 dfa9dfa635559a690cae20e4b5d98067 520 Gene3D G3DSA:3.40.605.10 45 291 1.6E-77 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAK77_RS18175 dfa9dfa635559a690cae20e4b5d98067 520 Pfam PF00171 Aldehyde dehydrogenase family 46 500 4.7E-133 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAK77_RS18175 dfa9dfa635559a690cae20e4b5d98067 520 Gene3D G3DSA:3.40.309.10 292 468 1.0E-52 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAK77_RS18175 dfa9dfa635559a690cae20e4b5d98067 520 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 276 283 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CAK77_RS22790 070c06038b12774eb2781c99daf2c330 362 SMART SM01002 148 310 3.5E-77 T 06-07-2017 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain CAK77_RS22790 070c06038b12774eb2781c99daf2c330 362 Gene3D G3DSA:3.40.50.1770 197 359 5.5E-36 T 06-07-2017 CAK77_RS22790 070c06038b12774eb2781c99daf2c330 362 SUPERFAMILY SSF52283 7 170 3.4E-45 T 06-07-2017 CAK77_RS22790 070c06038b12774eb2781c99daf2c330 362 Gene3D G3DSA:3.40.50.1770 7 174 3.3E-53 T 06-07-2017 CAK77_RS22790 070c06038b12774eb2781c99daf2c330 362 Gene3D G3DSA:3.50.50.60 175 196 3.4E-4 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS22790 070c06038b12774eb2781c99daf2c330 362 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 143 359 4.9E-65 T 06-07-2017 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain CAK77_RS22790 070c06038b12774eb2781c99daf2c330 362 SMART SM01003 9 139 2.3E-55 T 06-07-2017 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal CAK77_RS22790 070c06038b12774eb2781c99daf2c330 362 SUPERFAMILY SSF51735 139 314 1.05E-37 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS22790 070c06038b12774eb2781c99daf2c330 362 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 9 139 6.5E-39 T 06-07-2017 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal CAK77_RS13535 21ae293ce4315ff1fe05de1a9a6ee0e0 306 Pfam PF10128 Glucose-6-phosphate dehydrogenase subunit 56 297 8.0E-79 T 06-07-2017 IPR004555 Glucose-6-phosphate dehydrogenase assembly protein OpcA CAK77_RS13535 21ae293ce4315ff1fe05de1a9a6ee0e0 306 TIGRFAM TIGR00534 OpcA: glucose-6-phosphate dehydrogenase assembly protein OpcA 5 305 9.3E-100 T 06-07-2017 IPR004555 Glucose-6-phosphate dehydrogenase assembly protein OpcA CAK77_RS15375 683e856083d2440c9bec9a67827b9cda 229 Gene3D G3DSA:3.40.30.10 57 218 2.0E-16 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK77_RS15375 683e856083d2440c9bec9a67827b9cda 229 Pfam PF13462 Thioredoxin 62 220 1.3E-8 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK77_RS15375 683e856083d2440c9bec9a67827b9cda 229 SUPERFAMILY SSF52833 51 225 1.12E-17 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK77_RS05355 88cef673c863160f5b09df9d1cc4e78d 617 Pfam PF00005 ABC transporter 428 562 1.2E-15 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK77_RS05355 88cef673c863160f5b09df9d1cc4e78d 617 Gene3D G3DSA:1.20.1560.10 115 391 3.3E-6 T 06-07-2017 CAK77_RS05355 88cef673c863160f5b09df9d1cc4e78d 617 SUPERFAMILY SSF52540 410 595 1.87E-29 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS05355 88cef673c863160f5b09df9d1cc4e78d 617 Pfam PF06472 ABC transporter transmembrane region 2 41 343 2.2E-63 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAK77_RS05355 88cef673c863160f5b09df9d1cc4e78d 617 SMART SM00382 436 604 3.9E-8 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS05355 88cef673c863160f5b09df9d1cc4e78d 617 SUPERFAMILY SSF90123 61 391 8.37E-12 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAK77_RS05355 88cef673c863160f5b09df9d1cc4e78d 617 ProSitePatterns PS00211 ABC transporters family signature. 534 548 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK77_RS05355 88cef673c863160f5b09df9d1cc4e78d 617 Gene3D G3DSA:3.40.50.300 414 591 2.9E-30 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS17600 3cd7553091b1bd5eca083c01b4a1799f 361 Pfam PF07885 Ion channel 54 135 8.4E-13 T 06-07-2017 IPR013099 Potassium channel domain CAK77_RS17600 3cd7553091b1bd5eca083c01b4a1799f 361 Gene3D G3DSA:1.10.287.70 46 144 3.2E-14 T 06-07-2017 CAK77_RS17600 3cd7553091b1bd5eca083c01b4a1799f 361 Pfam PF02254 TrkA-N domain 156 272 1.3E-25 T 06-07-2017 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 CAK77_RS17600 3cd7553091b1bd5eca083c01b4a1799f 361 SUPERFAMILY SSF81324 29 173 2.09E-22 T 06-07-2017 CAK77_RS17600 3cd7553091b1bd5eca083c01b4a1799f 361 SUPERFAMILY SSF51735 151 295 9.19E-27 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS17600 3cd7553091b1bd5eca083c01b4a1799f 361 Gene3D G3DSA:3.40.50.720 147 282 1.7E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS15805 48eb2d8f2c41ab733022b8b04e7ff033 198 SMART SM00530 18 73 1.8E-16 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAK77_RS15805 48eb2d8f2c41ab733022b8b04e7ff033 198 Gene3D G3DSA:1.10.260.40 8 85 6.0E-21 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK77_RS15805 48eb2d8f2c41ab733022b8b04e7ff033 198 Pfam PF07883 Cupin domain 113 181 8.2E-13 T 06-07-2017 IPR013096 Cupin 2, conserved barrel CAK77_RS15805 48eb2d8f2c41ab733022b8b04e7ff033 198 SUPERFAMILY SSF51182 69 181 7.6E-23 T 06-07-2017 IPR011051 RmlC-like cupin domain CAK77_RS15805 48eb2d8f2c41ab733022b8b04e7ff033 198 SUPERFAMILY SSF47413 11 77 9.57E-18 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK77_RS15805 48eb2d8f2c41ab733022b8b04e7ff033 198 Pfam PF01381 Helix-turn-helix 19 73 2.3E-15 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAK77_RS15805 48eb2d8f2c41ab733022b8b04e7ff033 198 Gene3D G3DSA:2.60.120.10 91 184 2.9E-13 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK77_RS03000 9c9ae551a635f392a7d9fd997071b9eb 844 SUPERFAMILY SSF56784 25 250 2.79E-35 T 06-07-2017 IPR023214 HAD-like domain CAK77_RS03000 9c9ae551a635f392a7d9fd997071b9eb 844 Pfam PF00723 Glycosyl hydrolases family 15 480 840 1.7E-34 T 06-07-2017 IPR011613 Glycoside hydrolase family 15/Phosphorylase b kinase regulatory chain family Reactome: R-HSA-70221 CAK77_RS03000 9c9ae551a635f392a7d9fd997071b9eb 844 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 25 217 2.9E-14 T 06-07-2017 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CAK77_RS03000 9c9ae551a635f392a7d9fd997071b9eb 844 Gene3D G3DSA:3.40.50.1000 24 100 1.0E-36 T 06-07-2017 IPR023214 HAD-like domain CAK77_RS03000 9c9ae551a635f392a7d9fd997071b9eb 844 Gene3D G3DSA:3.40.50.1000 174 255 1.0E-36 T 06-07-2017 IPR023214 HAD-like domain CAK77_RS03000 9c9ae551a635f392a7d9fd997071b9eb 844 Pfam PF02358 Trehalose-phosphatase 29 217 8.8E-30 T 06-07-2017 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 CAK77_RS03000 9c9ae551a635f392a7d9fd997071b9eb 844 Gene3D G3DSA:1.50.10.10 475 841 3.2E-75 T 06-07-2017 IPR012341 Six-hairpin glycosidase GO:0003824 CAK77_RS03000 9c9ae551a635f392a7d9fd997071b9eb 844 TIGRFAM TIGR00685 T6PP: trehalose-phosphatase 24 249 3.1E-36 T 06-07-2017 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 CAK77_RS03000 9c9ae551a635f392a7d9fd997071b9eb 844 SUPERFAMILY SSF48208 457 837 5.44E-90 T 06-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 CAK77_RS18320 267a34a9f6ce1b425e92c7cf9658cfb3 302 Pfam PF08281 Sigma-70, region 4 113 161 7.7E-11 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS18320 267a34a9f6ce1b425e92c7cf9658cfb3 302 SUPERFAMILY SSF88659 107 162 1.55E-9 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS18320 267a34a9f6ce1b425e92c7cf9658cfb3 302 SUPERFAMILY SSF88946 11 89 1.1E-13 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS18320 267a34a9f6ce1b425e92c7cf9658cfb3 302 Pfam PF12680 SnoaL-like domain 179 282 3.4E-6 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain CAK77_RS18320 267a34a9f6ce1b425e92c7cf9658cfb3 302 Gene3D G3DSA:1.10.10.10 106 161 1.6E-10 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS18320 267a34a9f6ce1b425e92c7cf9658cfb3 302 Gene3D G3DSA:3.10.450.50 162 293 5.7E-11 T 06-07-2017 IPR032710 NTF2-like domain CAK77_RS18320 267a34a9f6ce1b425e92c7cf9658cfb3 302 Pfam PF04542 Sigma-70 region 2 12 72 4.9E-13 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS18320 267a34a9f6ce1b425e92c7cf9658cfb3 302 Gene3D G3DSA:1.10.1740.10 11 73 1.2E-12 T 06-07-2017 CAK77_RS18320 267a34a9f6ce1b425e92c7cf9658cfb3 302 SUPERFAMILY SSF54427 173 296 3.32E-16 T 06-07-2017 IPR032710 NTF2-like domain CAK77_RS18320 267a34a9f6ce1b425e92c7cf9658cfb3 302 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 12 160 2.5E-15 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS02410 d453fc4b7c74624732beffb1a331620e 660 Gene3D G3DSA:2.70.150.10 90 238 1.0E-25 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 CAK77_RS02410 d453fc4b7c74624732beffb1a331620e 660 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 87 629 8.3E-151 T 06-07-2017 CAK77_RS02410 d453fc4b7c74624732beffb1a331620e 660 SUPERFAMILY SSF56784 402 624 3.44E-49 T 06-07-2017 IPR023214 HAD-like domain CAK77_RS02410 d453fc4b7c74624732beffb1a331620e 660 SUPERFAMILY SSF56784 334 354 3.44E-49 T 06-07-2017 IPR023214 HAD-like domain CAK77_RS02410 d453fc4b7c74624732beffb1a331620e 660 Gene3D G3DSA:3.40.1110.10 326 354 8.3E-6 T 06-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CAK77_RS02410 d453fc4b7c74624732beffb1a331620e 660 Gene3D G3DSA:3.40.1110.10 355 453 1.0E-14 T 06-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CAK77_RS02410 d453fc4b7c74624732beffb1a331620e 660 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 110 604 2.4E-79 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CAK77_RS02410 d453fc4b7c74624732beffb1a331620e 660 SUPERFAMILY SSF81653 140 236 3.14E-23 T 06-07-2017 CAK77_RS02410 d453fc4b7c74624732beffb1a331620e 660 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 88 627 2.5E-171 T 06-07-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CAK77_RS02410 d453fc4b7c74624732beffb1a331620e 660 Pfam PF00702 haloacid dehalogenase-like hydrolase 332 539 1.4E-39 T 06-07-2017 CAK77_RS02410 d453fc4b7c74624732beffb1a331620e 660 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 187 201 2.3E-28 T 06-07-2017 CAK77_RS02410 d453fc4b7c74624732beffb1a331620e 660 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 549 561 2.3E-28 T 06-07-2017 CAK77_RS02410 d453fc4b7c74624732beffb1a331620e 660 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 473 483 2.3E-28 T 06-07-2017 CAK77_RS02410 d453fc4b7c74624732beffb1a331620e 660 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 451 462 2.3E-28 T 06-07-2017 CAK77_RS02410 d453fc4b7c74624732beffb1a331620e 660 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 525 544 2.3E-28 T 06-07-2017 CAK77_RS02410 d453fc4b7c74624732beffb1a331620e 660 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 336 350 2.3E-28 T 06-07-2017 CAK77_RS02410 d453fc4b7c74624732beffb1a331620e 660 Gene3D G3DSA:3.40.50.1000 454 594 1.4E-41 T 06-07-2017 IPR023214 HAD-like domain CAK77_RS02410 d453fc4b7c74624732beffb1a331620e 660 SUPERFAMILY SSF81665 89 141 6.15E-13 T 06-07-2017 CAK77_RS02410 d453fc4b7c74624732beffb1a331620e 660 SUPERFAMILY SSF81665 238 330 6.15E-13 T 06-07-2017 CAK77_RS02410 d453fc4b7c74624732beffb1a331620e 660 SUPERFAMILY SSF81665 578 601 6.15E-13 T 06-07-2017 CAK77_RS02410 d453fc4b7c74624732beffb1a331620e 660 Pfam PF00122 E1-E2 ATPase 108 327 6.7E-57 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 CAK77_RS02410 d453fc4b7c74624732beffb1a331620e 660 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 338 344 - T 06-07-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CAK77_RS00180 d453fc4b7c74624732beffb1a331620e 660 Gene3D G3DSA:2.70.150.10 90 238 1.0E-25 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 CAK77_RS00180 d453fc4b7c74624732beffb1a331620e 660 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 87 629 8.3E-151 T 06-07-2017 CAK77_RS00180 d453fc4b7c74624732beffb1a331620e 660 SUPERFAMILY SSF56784 402 624 3.44E-49 T 06-07-2017 IPR023214 HAD-like domain CAK77_RS00180 d453fc4b7c74624732beffb1a331620e 660 SUPERFAMILY SSF56784 334 354 3.44E-49 T 06-07-2017 IPR023214 HAD-like domain CAK77_RS00180 d453fc4b7c74624732beffb1a331620e 660 Gene3D G3DSA:3.40.1110.10 326 354 8.3E-6 T 06-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CAK77_RS00180 d453fc4b7c74624732beffb1a331620e 660 Gene3D G3DSA:3.40.1110.10 355 453 1.0E-14 T 06-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CAK77_RS00180 d453fc4b7c74624732beffb1a331620e 660 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 110 604 2.4E-79 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CAK77_RS00180 d453fc4b7c74624732beffb1a331620e 660 SUPERFAMILY SSF81653 140 236 3.14E-23 T 06-07-2017 CAK77_RS00180 d453fc4b7c74624732beffb1a331620e 660 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 88 627 2.5E-171 T 06-07-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CAK77_RS00180 d453fc4b7c74624732beffb1a331620e 660 Pfam PF00702 haloacid dehalogenase-like hydrolase 332 539 1.4E-39 T 06-07-2017 CAK77_RS00180 d453fc4b7c74624732beffb1a331620e 660 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 187 201 2.3E-28 T 06-07-2017 CAK77_RS00180 d453fc4b7c74624732beffb1a331620e 660 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 549 561 2.3E-28 T 06-07-2017 CAK77_RS00180 d453fc4b7c74624732beffb1a331620e 660 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 473 483 2.3E-28 T 06-07-2017 CAK77_RS00180 d453fc4b7c74624732beffb1a331620e 660 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 451 462 2.3E-28 T 06-07-2017 CAK77_RS00180 d453fc4b7c74624732beffb1a331620e 660 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 525 544 2.3E-28 T 06-07-2017 CAK77_RS00180 d453fc4b7c74624732beffb1a331620e 660 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 336 350 2.3E-28 T 06-07-2017 CAK77_RS00180 d453fc4b7c74624732beffb1a331620e 660 Gene3D G3DSA:3.40.50.1000 454 594 1.4E-41 T 06-07-2017 IPR023214 HAD-like domain CAK77_RS00180 d453fc4b7c74624732beffb1a331620e 660 SUPERFAMILY SSF81665 89 141 6.15E-13 T 06-07-2017 CAK77_RS00180 d453fc4b7c74624732beffb1a331620e 660 SUPERFAMILY SSF81665 238 330 6.15E-13 T 06-07-2017 CAK77_RS00180 d453fc4b7c74624732beffb1a331620e 660 SUPERFAMILY SSF81665 578 601 6.15E-13 T 06-07-2017 CAK77_RS00180 d453fc4b7c74624732beffb1a331620e 660 Pfam PF00122 E1-E2 ATPase 108 327 6.7E-57 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 CAK77_RS00180 d453fc4b7c74624732beffb1a331620e 660 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 338 344 - T 06-07-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CAK77_RS09735 739473db67e7ac6424fe42c40da49dd6 491 Gene3D G3DSA:3.90.190.20 340 487 7.9E-39 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CAK77_RS09735 739473db67e7ac6424fe42c40da49dd6 491 SUPERFAMILY SSF53244 341 485 2.93E-29 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CAK77_RS09735 739473db67e7ac6424fe42c40da49dd6 491 Pfam PF01225 Mur ligase family, catalytic domain 31 81 1.4E-10 T 06-07-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CAK77_RS09735 739473db67e7ac6424fe42c40da49dd6 491 SUPERFAMILY SSF63418 2 94 2.49E-17 T 06-07-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CAK77_RS09735 739473db67e7ac6424fe42c40da49dd6 491 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 1 486 30.21 T 06-07-2017 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK77_RS09735 739473db67e7ac6424fe42c40da49dd6 491 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 33 483 4.9E-128 T 06-07-2017 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK77_RS09735 739473db67e7ac6424fe42c40da49dd6 491 Pfam PF08245 Mur ligase middle domain 131 318 3.3E-41 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAK77_RS09735 739473db67e7ac6424fe42c40da49dd6 491 SUPERFAMILY SSF53623 126 335 6.15E-51 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAK77_RS09735 739473db67e7ac6424fe42c40da49dd6 491 Gene3D G3DSA:3.40.1190.10 107 333 1.2E-63 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAK77_RS09735 739473db67e7ac6424fe42c40da49dd6 491 Pfam PF02875 Mur ligase family, glutamate ligase domain 340 429 5.8E-22 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CAK77_RS09735 739473db67e7ac6424fe42c40da49dd6 491 Gene3D G3DSA:3.40.1390.10 1 81 3.0E-21 T 06-07-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CAK77_RS12455 86beefe9d2ff3bcf8df43d5c32532202 292 Gene3D G3DSA:3.40.50.620 11 150 2.7E-34 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS12455 86beefe9d2ff3bcf8df43d5c32532202 292 SUPERFAMILY SSF52402 158 290 6.87E-31 T 06-07-2017 CAK77_RS12455 86beefe9d2ff3bcf8df43d5c32532202 292 PRINTS PR01438 Universal stress protein signature 268 290 1.1E-15 T 06-07-2017 IPR006015 Universal stress protein A CAK77_RS12455 86beefe9d2ff3bcf8df43d5c32532202 292 PRINTS PR01438 Universal stress protein signature 156 174 1.1E-15 T 06-07-2017 IPR006015 Universal stress protein A CAK77_RS12455 86beefe9d2ff3bcf8df43d5c32532202 292 PRINTS PR01438 Universal stress protein signature 250 262 1.1E-15 T 06-07-2017 IPR006015 Universal stress protein A CAK77_RS12455 86beefe9d2ff3bcf8df43d5c32532202 292 SUPERFAMILY SSF52402 11 150 6.2E-30 T 06-07-2017 CAK77_RS12455 86beefe9d2ff3bcf8df43d5c32532202 292 Pfam PF00582 Universal stress protein family 11 148 7.7E-27 T 06-07-2017 IPR006016 UspA GO:0006950 CAK77_RS12455 86beefe9d2ff3bcf8df43d5c32532202 292 Pfam PF00582 Universal stress protein family 159 290 1.5E-26 T 06-07-2017 IPR006016 UspA GO:0006950 CAK77_RS12455 86beefe9d2ff3bcf8df43d5c32532202 292 Gene3D G3DSA:3.40.50.620 151 290 3.5E-33 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS08510 7944a7736b602e8f9a74f2920813ffd0 435 Pfam PF01595 Domain of unknown function DUF21 9 185 3.9E-30 T 06-07-2017 IPR002550 Domain of unknown function DUF21 CAK77_RS08510 7944a7736b602e8f9a74f2920813ffd0 435 SMART SM01091 339 422 4.5E-16 T 06-07-2017 IPR005170 Transporter-associated domain CAK77_RS08510 7944a7736b602e8f9a74f2920813ffd0 435 Pfam PF03471 Transporter associated domain 340 396 2.8E-11 T 06-07-2017 IPR005170 Transporter-associated domain CAK77_RS08510 7944a7736b602e8f9a74f2920813ffd0 435 SMART SM00116 209 258 0.17 T 06-07-2017 IPR000644 CBS domain CAK77_RS08510 7944a7736b602e8f9a74f2920813ffd0 435 SMART SM00116 275 323 0.12 T 06-07-2017 IPR000644 CBS domain CAK77_RS08510 7944a7736b602e8f9a74f2920813ffd0 435 Gene3D G3DSA:3.30.465.10 332 413 2.4E-22 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAK77_RS08510 7944a7736b602e8f9a74f2920813ffd0 435 SUPERFAMILY SSF56176 338 429 3.54E-12 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAK77_RS08510 7944a7736b602e8f9a74f2920813ffd0 435 Gene3D G3DSA:3.10.580.10 185 331 6.6E-24 T 06-07-2017 CAK77_RS08510 7944a7736b602e8f9a74f2920813ffd0 435 Pfam PF00571 CBS domain 202 255 2.5E-4 T 06-07-2017 IPR000644 CBS domain CAK77_RS08510 7944a7736b602e8f9a74f2920813ffd0 435 Pfam PF00571 CBS domain 269 323 3.4E-7 T 06-07-2017 IPR000644 CBS domain CAK77_RS08510 7944a7736b602e8f9a74f2920813ffd0 435 SUPERFAMILY SSF54631 195 334 1.04E-35 T 06-07-2017 CAK77_RS22920 114bd20072e38943ce0aaa053196985b 472 SUPERFAMILY SSF53720 23 460 1.19E-115 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAK77_RS22920 114bd20072e38943ce0aaa053196985b 472 PIRSF PIRSF036492 4 472 3.3E-170 T 06-07-2017 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0004030|GO:0006081|GO:0055114 CAK77_RS22920 114bd20072e38943ce0aaa053196985b 472 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 226 233 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CAK77_RS22920 114bd20072e38943ce0aaa053196985b 472 Pfam PF00171 Aldehyde dehydrogenase family 19 443 2.2E-86 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAK77_RS22920 114bd20072e38943ce0aaa053196985b 472 Gene3D G3DSA:3.40.309.10 241 424 2.5E-56 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAK77_RS22920 114bd20072e38943ce0aaa053196985b 472 Gene3D G3DSA:3.40.605.10 16 240 1.5E-55 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAK77_RS05945 4d2bc64e19dc4fb8998e9ce0b8efc644 165 SMART SM00347 46 147 1.7E-17 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK77_RS05945 4d2bc64e19dc4fb8998e9ce0b8efc644 165 Gene3D G3DSA:1.10.10.10 29 159 6.3E-31 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS05945 4d2bc64e19dc4fb8998e9ce0b8efc644 165 ProSitePatterns PS01117 MarR-type HTH domain signature. 87 121 - T 06-07-2017 IPR023187 Transcriptional regulator MarR-type, conserved site CAK77_RS05945 4d2bc64e19dc4fb8998e9ce0b8efc644 165 SUPERFAMILY SSF46785 28 159 1.52E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS05945 4d2bc64e19dc4fb8998e9ce0b8efc644 165 Pfam PF12802 MarR family 51 112 7.1E-13 T 06-07-2017 CAK77_RS23130 76b2cf0ae66aa94d678b2f665c8868d7 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 62 5.3E-18 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS23130 76b2cf0ae66aa94d678b2f665c8868d7 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 8.9E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS23130 76b2cf0ae66aa94d678b2f665c8868d7 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 8.9E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS23130 76b2cf0ae66aa94d678b2f665c8868d7 194 SUPERFAMILY SSF46689 15 69 4.71E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS23130 76b2cf0ae66aa94d678b2f665c8868d7 194 Gene3D G3DSA:1.10.357.10 15 191 2.9E-24 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS23095 07dc10da2458c98978a09a063b3192d3 613 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 18 609 1.5E-232 T 06-07-2017 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CAK77_RS23095 07dc10da2458c98978a09a063b3192d3 613 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 4 610 45.107 T 06-07-2017 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CAK77_RS23095 07dc10da2458c98978a09a063b3192d3 613 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 122 132 - T 06-07-2017 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CAK77_RS23095 07dc10da2458c98978a09a063b3192d3 613 SUPERFAMILY SSF52016 423 610 5.02E-58 T 06-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CAK77_RS23095 07dc10da2458c98978a09a063b3192d3 613 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 511 522 - T 06-07-2017 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CAK77_RS23095 07dc10da2458c98978a09a063b3192d3 613 SUPERFAMILY SSF143975 4 422 3.92E-131 T 06-07-2017 CAK77_RS23095 07dc10da2458c98978a09a063b3192d3 613 Pfam PF00920 Dehydratase family 34 607 8.8E-214 T 06-07-2017 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CAK77_RS18305 10c39ff9236dea81d093f41ebd5f4fc3 584 Gene3D G3DSA:1.20.58.100 427 543 5.5E-39 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK77_RS18305 10c39ff9236dea81d093f41ebd5f4fc3 584 SUPERFAMILY SSF56425 237 355 6.88E-42 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK77_RS18305 10c39ff9236dea81d093f41ebd5f4fc3 584 Pfam PF00890 FAD binding domain 8 401 6.3E-112 T 06-07-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK77_RS18305 10c39ff9236dea81d093f41ebd5f4fc3 584 Pfam PF02910 Fumarate reductase flavoprotein C-term 455 584 1.3E-44 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK77_RS18305 10c39ff9236dea81d093f41ebd5f4fc3 584 PIRSF PIRSF000171 1 578 2.2E-44 T 06-07-2017 IPR030664 Succinate dehydrogenase/fumarate reductase, alpha/adenylylsulphate reductase subunit Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK77_RS18305 10c39ff9236dea81d093f41ebd5f4fc3 584 TIGRFAM TIGR01816 sdhA_forward: succinate dehydrogenase, flavoprotein subunit 5 584 1.0E-300 T 06-07-2017 IPR011281 Succinate dehydrogenase, flavoprotein subunit GO:0006099|GO:0016627|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK77_RS18305 10c39ff9236dea81d093f41ebd5f4fc3 584 Gene3D G3DSA:4.10.80.40 544 580 1.8E-16 T 06-07-2017 CAK77_RS18305 10c39ff9236dea81d093f41ebd5f4fc3 584 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 379 386 3.4E-5 T 06-07-2017 CAK77_RS18305 10c39ff9236dea81d093f41ebd5f4fc3 584 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 8 30 3.4E-5 T 06-07-2017 CAK77_RS18305 10c39ff9236dea81d093f41ebd5f4fc3 584 Gene3D G3DSA:3.90.700.10 244 349 6.4E-39 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK77_RS18305 10c39ff9236dea81d093f41ebd5f4fc3 584 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 41 50 - T 06-07-2017 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK77_RS18305 10c39ff9236dea81d093f41ebd5f4fc3 584 Gene3D G3DSA:3.50.50.60 351 422 2.5E-115 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS18305 10c39ff9236dea81d093f41ebd5f4fc3 584 Gene3D G3DSA:3.50.50.60 3 243 2.5E-115 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS18305 10c39ff9236dea81d093f41ebd5f4fc3 584 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 8 584 7.4E-259 T 06-07-2017 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK77_RS18305 10c39ff9236dea81d093f41ebd5f4fc3 584 SUPERFAMILY SSF51905 359 434 7.08E-73 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS18305 10c39ff9236dea81d093f41ebd5f4fc3 584 SUPERFAMILY SSF51905 3 260 7.08E-73 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS18305 10c39ff9236dea81d093f41ebd5f4fc3 584 SUPERFAMILY SSF46977 447 584 5.1E-48 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK77_RS22100 153023671c473d00862744655ea126e9 265 SUPERFAMILY SSF52096 1 262 1.17E-68 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS22100 153023671c473d00862744655ea126e9 265 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 106 126 - T 06-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CAK77_RS22100 153023671c473d00862744655ea126e9 265 Gene3D G3DSA:3.90.226.10 2 219 1.2E-58 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS22100 153023671c473d00862744655ea126e9 265 Gene3D G3DSA:1.10.12.10 220 263 1.8E-6 T 06-07-2017 IPR014748 Crontonase, C-terminal CAK77_RS22100 153023671c473d00862744655ea126e9 265 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 261 6.4E-38 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAK77_RS10000 1a3ec90b7c9328234e9d53bcec503cc3 255 Gene3D G3DSA:1.10.12.10 198 255 2.6E-18 T 06-07-2017 IPR014748 Crontonase, C-terminal CAK77_RS10000 1a3ec90b7c9328234e9d53bcec503cc3 255 Gene3D G3DSA:3.90.226.10 3 195 7.5E-57 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS10000 1a3ec90b7c9328234e9d53bcec503cc3 255 Pfam PF00378 Enoyl-CoA hydratase/isomerase 12 254 1.4E-58 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAK77_RS10000 1a3ec90b7c9328234e9d53bcec503cc3 255 SUPERFAMILY SSF52096 4 255 2.66E-77 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS13100 ee44c9a1d90606095c5f391e319a4976 298 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 130 297 7.9E-61 T 06-07-2017 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CAK77_RS13100 ee44c9a1d90606095c5f391e319a4976 298 Gene3D G3DSA:3.20.20.70 151 288 2.1E-55 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK77_RS13100 ee44c9a1d90606095c5f391e319a4976 298 Gene3D G3DSA:3.90.1170.20 22 150 9.4E-43 T 06-07-2017 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 CAK77_RS13100 ee44c9a1d90606095c5f391e319a4976 298 PIRSF PIRSF006250 18 298 5.2E-101 T 06-07-2017 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 CAK77_RS13100 ee44c9a1d90606095c5f391e319a4976 298 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 40 128 2.2E-20 T 06-07-2017 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 CAK77_RS13100 ee44c9a1d90606095c5f391e319a4976 298 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 28 298 3.9E-95 T 06-07-2017 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 CAK77_RS13100 ee44c9a1d90606095c5f391e319a4976 298 SUPERFAMILY SSF51690 130 298 4.71E-56 T 06-07-2017 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CAK77_RS13100 ee44c9a1d90606095c5f391e319a4976 298 SUPERFAMILY SSF54675 24 129 3.83E-27 T 06-07-2017 CAK77_RS10695 c0a6ee06a751238f368f3ffb24058913 251 SUPERFAMILY SSF53790 2 232 4.06E-62 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAK77_RS10695 c0a6ee06a751238f368f3ffb24058913 251 Gene3D G3DSA:3.30.950.10 111 233 3.5E-36 T 06-07-2017 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAK77_RS10695 c0a6ee06a751238f368f3ffb24058913 251 Gene3D G3DSA:3.40.1010.10 2 110 3.4E-30 T 06-07-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAK77_RS10695 c0a6ee06a751238f368f3ffb24058913 251 TIGRFAM TIGR01465 cobM_cbiF: precorrin-4 C11-methyltransferase 3 243 4.5E-90 T 06-07-2017 IPR006362 Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase GO:0009236|GO:0046026 CAK77_RS10695 c0a6ee06a751238f368f3ffb24058913 251 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 2 209 9.3E-41 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAK77_RS10695 c0a6ee06a751238f368f3ffb24058913 251 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 6 20 - T 06-07-2017 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CAK77_RS20590 0e35872249a730b8e501c1ea1a4d86c1 268 Gene3D G3DSA:3.40.50.150 163 232 9.3E-4 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS20590 0e35872249a730b8e501c1ea1a4d86c1 268 SUPERFAMILY SSF53335 167 234 4.03E-11 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS20590 0e35872249a730b8e501c1ea1a4d86c1 268 SUPERFAMILY SSF53335 76 135 4.03E-11 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS20590 0e35872249a730b8e501c1ea1a4d86c1 268 Pfam PF05711 Macrocin-O-methyltransferase (TylF) 10 267 1.4E-114 T 06-07-2017 IPR008884 Macrocin-O-methyltransferase CAK77_RS05230 bef35fd238755b8645332f3d8f219d78 287 Pfam PF06827 Zinc finger found in FPG and IleRS 246 271 2.4E-6 T 06-07-2017 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 CAK77_RS05230 bef35fd238755b8645332f3d8f219d78 287 Gene3D G3DSA:1.10.8.50 140 272 1.6E-32 T 06-07-2017 CAK77_RS05230 bef35fd238755b8645332f3d8f219d78 287 SUPERFAMILY SSF57716 228 272 1.08E-10 T 06-07-2017 CAK77_RS05230 bef35fd238755b8645332f3d8f219d78 287 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 139 220 6.9E-16 T 06-07-2017 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 CAK77_RS05230 bef35fd238755b8645332f3d8f219d78 287 SUPERFAMILY SSF81624 2 144 6.06E-22 T 06-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CAK77_RS05230 bef35fd238755b8645332f3d8f219d78 287 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 85 9.4E-14 T 06-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CAK77_RS05230 bef35fd238755b8645332f3d8f219d78 287 SUPERFAMILY SSF46946 139 219 4.84E-19 T 06-07-2017 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 CAK77_RS05230 bef35fd238755b8645332f3d8f219d78 287 Gene3D G3DSA:3.20.190.10 2 139 1.4E-17 T 06-07-2017 CAK77_RS05230 bef35fd238755b8645332f3d8f219d78 287 SMART SM00898 2 125 2.0E-24 T 06-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CAK77_RS05230 bef35fd238755b8645332f3d8f219d78 287 SMART SM01232 139 229 1.8E-25 T 06-07-2017 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 CAK77_RS09015 488aa2255e1ea29bb4702b2d21b1a3a2 306 Pfam PF13602 Zinc-binding dehydrogenase 206 304 6.7E-11 T 06-07-2017 CAK77_RS09015 488aa2255e1ea29bb4702b2d21b1a3a2 306 Gene3D G3DSA:3.90.180.10 1 195 7.8E-48 T 06-07-2017 IPR011032 GroES-like CAK77_RS09015 488aa2255e1ea29bb4702b2d21b1a3a2 306 SMART SM00829 10 304 6.5E-12 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAK77_RS09015 488aa2255e1ea29bb4702b2d21b1a3a2 306 SUPERFAMILY SSF50129 1 155 1.29E-27 T 06-07-2017 IPR011032 GroES-like CAK77_RS09015 488aa2255e1ea29bb4702b2d21b1a3a2 306 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 148 169 - T 06-07-2017 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 CAK77_RS09015 488aa2255e1ea29bb4702b2d21b1a3a2 306 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 90 1.9E-6 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAK77_RS09015 488aa2255e1ea29bb4702b2d21b1a3a2 306 SUPERFAMILY SSF51735 121 244 1.24E-22 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS16405 e09f0020ac3ae63c6ddf8219305ee8a5 233 SUPERFAMILY SSF55781 62 233 1.9E-36 T 06-07-2017 IPR029016 GAF domain-like CAK77_RS16405 e09f0020ac3ae63c6ddf8219305ee8a5 233 SUPERFAMILY SSF46785 8 75 1.26E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS16405 e09f0020ac3ae63c6ddf8219305ee8a5 233 Gene3D G3DSA:1.10.10.10 5 65 2.9E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS16405 e09f0020ac3ae63c6ddf8219305ee8a5 233 Pfam PF09339 IclR helix-turn-helix domain 10 58 1.6E-12 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAK77_RS16405 e09f0020ac3ae63c6ddf8219305ee8a5 233 Pfam PF01614 Bacterial transcriptional regulator 124 229 9.1E-18 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAK77_RS16405 e09f0020ac3ae63c6ddf8219305ee8a5 233 Gene3D G3DSA:3.30.450.40 73 233 7.4E-41 T 06-07-2017 IPR029016 GAF domain-like CAK77_RS16405 e09f0020ac3ae63c6ddf8219305ee8a5 233 SMART SM00346 7 92 6.9E-26 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAK77_RS11715 7e581ea9281c6a58d7b1b95c08f8588a 484 SUPERFAMILY SSF48179 185 479 2.38E-121 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAK77_RS11715 7e581ea9281c6a58d7b1b95c08f8588a 484 SMART SM01350 187 476 3.5E-210 T 06-07-2017 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CAK77_RS11715 7e581ea9281c6a58d7b1b95c08f8588a 484 ProSitePatterns PS00461 6-phosphogluconate dehydrogenase signature. 262 274 - T 06-07-2017 IPR006184 6-phosphogluconate-binding site GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CAK77_RS11715 7e581ea9281c6a58d7b1b95c08f8588a 484 PIRSF PIRSF000109 7 484 2.2E-207 T 06-07-2017 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CAK77_RS11715 7e581ea9281c6a58d7b1b95c08f8588a 484 TIGRFAM TIGR00873 gnd: 6-phosphogluconate dehydrogenase (decarboxylating) 13 476 1.1E-218 T 06-07-2017 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CAK77_RS11715 7e581ea9281c6a58d7b1b95c08f8588a 484 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 187 475 1.3E-124 T 06-07-2017 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CAK77_RS11715 7e581ea9281c6a58d7b1b95c08f8588a 484 SUPERFAMILY SSF51735 12 185 7.71E-53 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS11715 7e581ea9281c6a58d7b1b95c08f8588a 484 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 13 182 5.9E-50 T 06-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CAK77_RS11715 7e581ea9281c6a58d7b1b95c08f8588a 484 Gene3D G3DSA:3.40.50.720 9 188 2.1E-57 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS11715 7e581ea9281c6a58d7b1b95c08f8588a 484 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 176 204 5.2E-81 T 06-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CAK77_RS11715 7e581ea9281c6a58d7b1b95c08f8588a 484 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 258 285 5.2E-81 T 06-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CAK77_RS11715 7e581ea9281c6a58d7b1b95c08f8588a 484 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 128 153 5.2E-81 T 06-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CAK77_RS11715 7e581ea9281c6a58d7b1b95c08f8588a 484 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 75 104 5.2E-81 T 06-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CAK77_RS11715 7e581ea9281c6a58d7b1b95c08f8588a 484 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 365 387 5.2E-81 T 06-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CAK77_RS11715 7e581ea9281c6a58d7b1b95c08f8588a 484 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 12 35 5.2E-81 T 06-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CAK77_RS11715 7e581ea9281c6a58d7b1b95c08f8588a 484 Gene3D G3DSA:1.10.1040.10 189 442 3.6E-109 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAK77_RS11715 7e581ea9281c6a58d7b1b95c08f8588a 484 Gene3D G3DSA:1.20.5.320 444 483 1.3E-20 T 06-07-2017 IPR012284 6-phosphogluconate dehydrogenase, domain 3 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CAK77_RS04110 75561163161b599920e9835396221099 306 Gene3D G3DSA:1.10.10.60 199 253 1.1E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS04110 75561163161b599920e9835396221099 306 SUPERFAMILY SSF46689 200 250 4.75E-8 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS04110 75561163161b599920e9835396221099 306 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 254 296 - T 06-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CAK77_RS04110 75561163161b599920e9835396221099 306 SMART SM00342 217 300 1.6E-25 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK77_RS04110 75561163161b599920e9835396221099 306 Pfam PF12833 Helix-turn-helix domain 223 301 3.4E-19 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK77_RS04110 75561163161b599920e9835396221099 306 Gene3D G3DSA:1.10.10.60 254 304 1.2E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS04110 75561163161b599920e9835396221099 306 SUPERFAMILY SSF46689 253 304 2.46E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS04110 75561163161b599920e9835396221099 306 Pfam PF12852 Cupin 25 185 2.6E-31 T 06-07-2017 IPR032783 AraC-type transcription regulator, ligand-binding domain CAK77_RS17895 a47750fcc8d2fef542049f4b139aa973 62 PRINTS PR00163 Rubredoxin signature 7 23 2.9E-7 T 06-07-2017 IPR024935 Rubredoxin domain GO:0005506 CAK77_RS17895 a47750fcc8d2fef542049f4b139aa973 62 PRINTS PR00163 Rubredoxin signature 37 53 2.9E-7 T 06-07-2017 IPR024935 Rubredoxin domain GO:0005506 CAK77_RS17895 a47750fcc8d2fef542049f4b139aa973 62 SUPERFAMILY SSF57802 4 51 3.44E-18 T 06-07-2017 CAK77_RS17895 a47750fcc8d2fef542049f4b139aa973 62 Pfam PF00301 Rubredoxin 7 54 3.9E-21 T 06-07-2017 IPR024935 Rubredoxin domain GO:0005506 CAK77_RS17895 a47750fcc8d2fef542049f4b139aa973 62 Gene3D G3DSA:2.20.28.10 3 57 1.1E-22 T 06-07-2017 IPR004039 Rubredoxin-type fold CAK77_RS17895 a47750fcc8d2fef542049f4b139aa973 62 ProSitePatterns PS00202 Rubredoxin signature. 37 47 - T 06-07-2017 IPR018527 Rubredoxin, iron-binding site GO:0046872 CAK77_RS03520 3a99797a98f15b2ec3af1b2d88c0a186 281 Pfam PF00561 alpha/beta hydrolase fold 25 265 2.6E-17 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS03520 3a99797a98f15b2ec3af1b2d88c0a186 281 PRINTS PR00412 Epoxide hydrolase signature 97 110 9.9E-17 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK77_RS03520 3a99797a98f15b2ec3af1b2d88c0a186 281 PRINTS PR00412 Epoxide hydrolase signature 253 275 9.9E-17 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK77_RS03520 3a99797a98f15b2ec3af1b2d88c0a186 281 PRINTS PR00412 Epoxide hydrolase signature 31 49 9.9E-17 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK77_RS03520 3a99797a98f15b2ec3af1b2d88c0a186 281 PRINTS PR00412 Epoxide hydrolase signature 51 66 9.9E-17 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK77_RS03520 3a99797a98f15b2ec3af1b2d88c0a186 281 PRINTS PR00412 Epoxide hydrolase signature 219 235 9.9E-17 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK77_RS03520 3a99797a98f15b2ec3af1b2d88c0a186 281 SUPERFAMILY SSF53474 5 278 5.72E-58 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS03520 3a99797a98f15b2ec3af1b2d88c0a186 281 Gene3D G3DSA:3.40.50.1820 6 278 2.4E-65 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS04750 a7f2a0cfe6154f0826d9f7f86f6d9cfa 147 SUPERFAMILY SSF55961 3 142 4.28E-20 T 06-07-2017 CAK77_RS04750 a7f2a0cfe6154f0826d9f7f86f6d9cfa 147 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 3 142 1.0E-18 T 06-07-2017 IPR019587 Polyketide cyclase/dehydrase CAK77_RS04750 a7f2a0cfe6154f0826d9f7f86f6d9cfa 147 Gene3D G3DSA:3.30.530.20 4 143 2.1E-16 T 06-07-2017 IPR023393 START-like domain CAK77_RS00600 bd5cd1f53ad942b176cf2f0ef880187e 305 PIRSF PIRSF007580 9 303 8.7E-84 T 06-07-2017 IPR016516 Uncharacterised conserved protein UCP07580 CAK77_RS00600 bd5cd1f53ad942b176cf2f0ef880187e 305 Pfam PF10118 Predicted metal-dependent hydrolase 25 283 2.7E-71 T 06-07-2017 IPR016516 Uncharacterised conserved protein UCP07580 CAK77_RS20880 77a8f15c5ff650fb53a9fe05173cca9a 343 Pfam PF00296 Luciferase-like monooxygenase 13 324 1.4E-72 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS20880 77a8f15c5ff650fb53a9fe05173cca9a 343 SUPERFAMILY SSF51679 1 335 8.37E-66 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS20880 77a8f15c5ff650fb53a9fe05173cca9a 343 Gene3D G3DSA:3.20.20.30 1 337 9.1E-75 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS20880 77a8f15c5ff650fb53a9fe05173cca9a 343 TIGRFAM TIGR03559 F420_Rv3520c: probable F420-dependent oxidoreductase, Rv3520c family 2 328 1.2E-151 T 06-07-2017 IPR019951 F420-dependent oxidoreductase-predicted, Rv3520c CAK77_RS01250 7a280d884809b0d0ea7e0976d788dc80 423 TIGRFAM TIGR03934 TQXA_dom: TQXA domain 104 157 1.7E-15 T 06-07-2017 IPR023849 Uncharacterised domain CHP03934, TQXA CAK77_RS07090 9de097f14348bc18a6d390c813adf007 578 Pfam PF00664 ABC transporter transmembrane region 23 292 8.8E-51 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAK77_RS07090 9de097f14348bc18a6d390c813adf007 578 Pfam PF00005 ABC transporter 355 503 1.5E-25 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK77_RS07090 9de097f14348bc18a6d390c813adf007 578 Gene3D G3DSA:3.40.50.300 337 568 4.5E-71 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS07090 9de097f14348bc18a6d390c813adf007 578 Gene3D G3DSA:1.20.1560.10 10 318 9.7E-64 T 06-07-2017 CAK77_RS07090 9de097f14348bc18a6d390c813adf007 578 ProSitePatterns PS00211 ABC transporters family signature. 476 490 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK77_RS07090 9de097f14348bc18a6d390c813adf007 578 SUPERFAMILY SSF52540 330 574 2.21E-80 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS07090 9de097f14348bc18a6d390c813adf007 578 SUPERFAMILY SSF90123 11 317 1.06E-69 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAK77_RS07090 9de097f14348bc18a6d390c813adf007 578 SMART SM00382 364 550 2.3E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS20505 ca1349ccc6d6f45217643fa580ab3337 665 SUPERFAMILY SSF160467 349 441 1.44E-18 T 06-07-2017 CAK77_RS20505 ca1349ccc6d6f45217643fa580ab3337 665 SUPERFAMILY SSF50891 465 599 8.72E-25 T 06-07-2017 IPR029000 Cyclophilin-like domain CAK77_RS20505 ca1349ccc6d6f45217643fa580ab3337 665 Gene3D G3DSA:2.40.100.10 465 606 2.2E-43 T 06-07-2017 IPR029000 Cyclophilin-like domain CAK77_RS20505 ca1349ccc6d6f45217643fa580ab3337 665 Gene3D G3DSA:2.40.100.10 180 310 1.1E-28 T 06-07-2017 IPR029000 Cyclophilin-like domain CAK77_RS20505 ca1349ccc6d6f45217643fa580ab3337 665 Gene3D G3DSA:3.30.1360.40 348 428 1.4E-26 T 06-07-2017 IPR024946 Arginine repressor C-terminal-like domain CAK77_RS20505 ca1349ccc6d6f45217643fa580ab3337 665 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 6 311 1.5E-80 T 06-07-2017 IPR003778 Carboxyltransferase domain, subdomain A and B CAK77_RS20505 ca1349ccc6d6f45217643fa580ab3337 665 Pfam PF02626 Allophanate hydrolase subunit 2 29 300 1.8E-83 T 06-07-2017 IPR003778 Carboxyltransferase domain, subdomain A and B CAK77_RS20505 ca1349ccc6d6f45217643fa580ab3337 665 SUPERFAMILY SSF50891 181 304 9.86E-30 T 06-07-2017 IPR029000 Cyclophilin-like domain CAK77_RS20505 ca1349ccc6d6f45217643fa580ab3337 665 SMART SM00796 348 583 1.3E-103 T 06-07-2017 IPR003833 Carboxyltransferase domain, subdomain C and D CAK77_RS20505 ca1349ccc6d6f45217643fa580ab3337 665 SMART SM00797 28 313 9.0E-144 T 06-07-2017 IPR003778 Carboxyltransferase domain, subdomain A and B CAK77_RS20505 ca1349ccc6d6f45217643fa580ab3337 665 Pfam PF02682 Allophanate hydrolase subunit 1 348 568 8.3E-49 T 06-07-2017 IPR003833 Carboxyltransferase domain, subdomain C and D CAK77_RS09530 9a2a6c5287913db4b76f8ac90276e7ee 139 Pfam PF12270 Cytochrome c oxidase subunit IV 1 137 9.5E-52 T 06-07-2017 IPR021050 Cytochrome c oxidase subunit IV, actinobacteria GO:0004129|GO:0016021|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 CAK77_RS09530 9a2a6c5287913db4b76f8ac90276e7ee 139 PIRSF PIRSF017385 1 139 2.3E-49 T 06-07-2017 IPR021050 Cytochrome c oxidase subunit IV, actinobacteria GO:0004129|GO:0016021|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 CAK77_RS04715 8bc8962abaf6b9662406c910c00931a0 243 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 90 110 - T 06-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CAK77_RS04715 8bc8962abaf6b9662406c910c00931a0 243 SUPERFAMILY SSF52096 3 242 3.21E-58 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS04715 8bc8962abaf6b9662406c910c00931a0 243 Gene3D G3DSA:3.90.226.10 3 241 1.0E-58 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS04715 8bc8962abaf6b9662406c910c00931a0 243 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 241 9.5E-36 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAK77_RS19740 7680ce6358bdb829507eae32802f7434 114 Pfam PF14542 GCN5-related N-acetyl-transferase 16 97 5.2E-22 T 06-07-2017 IPR031165 Yjdj-type Gcn5-related N-acetyltransferase CAK77_RS19740 7680ce6358bdb829507eae32802f7434 114 Gene3D G3DSA:3.40.630.30 6 99 1.3E-23 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS19740 7680ce6358bdb829507eae32802f7434 114 SUPERFAMILY SSF55729 6 101 3.17E-23 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS21895 7ee2616b7332b2c6c2824f3027d480c9 355 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 116 1.0E-21 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAK77_RS21895 7ee2616b7332b2c6c2824f3027d480c9 355 Gene3D G3DSA:3.40.50.720 186 298 3.7E-28 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS21895 7ee2616b7332b2c6c2824f3027d480c9 355 Pfam PF00107 Zinc-binding dehydrogenase 193 314 3.0E-22 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAK77_RS21895 7ee2616b7332b2c6c2824f3027d480c9 355 SUPERFAMILY SSF51735 155 320 1.31E-36 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS21895 7ee2616b7332b2c6c2824f3027d480c9 355 SUPERFAMILY SSF50129 2 189 1.22E-52 T 06-07-2017 IPR011032 GroES-like CAK77_RS21895 7ee2616b7332b2c6c2824f3027d480c9 355 SMART SM00829 6 353 1.6E-6 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAK77_RS21895 7ee2616b7332b2c6c2824f3027d480c9 355 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 57 71 - T 06-07-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CAK77_RS21895 7ee2616b7332b2c6c2824f3027d480c9 355 Gene3D G3DSA:3.90.180.10 2 185 3.0E-52 T 06-07-2017 IPR011032 GroES-like CAK77_RS07270 c54ab8d58d79c48480d45ec267d7a54f 177 Gene3D G3DSA:1.20.5.620 90 139 8.4E-6 T 06-07-2017 IPR028987 F-type ATP synthase subunit B-like, membrane domain CAK77_RS07270 c54ab8d58d79c48480d45ec267d7a54f 177 SUPERFAMILY SSF81573 90 140 1.96E-5 T 06-07-2017 IPR028987 F-type ATP synthase subunit B-like, membrane domain CAK77_RS07270 c54ab8d58d79c48480d45ec267d7a54f 177 Hamap MF_01398 ATP synthase subunit b [atpF]. 29 177 9.093 T 06-07-2017 IPR002146 ATPase, F0 complex, subunit B/B', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 CAK77_RS07270 c54ab8d58d79c48480d45ec267d7a54f 177 Pfam PF00430 ATP synthase B/B' CF(0) 34 164 2.3E-23 T 06-07-2017 IPR002146 ATPase, F0 complex, subunit B/B', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 CAK77_RS00215 93059c8691043b22b29e7b0cf3196b64 210 Pfam PF09167 Domain of unknown function (DUF1942) 33 156 1.8E-44 T 06-07-2017 IPR015250 MPT63-like GO:0005615 CAK77_RS00215 93059c8691043b22b29e7b0cf3196b64 210 SUPERFAMILY SSF81982 30 158 4.45E-48 T 06-07-2017 IPR015250 MPT63-like GO:0005615 CAK77_RS00215 93059c8691043b22b29e7b0cf3196b64 210 ProDom PD886639 ANTIGEN IMMUNOGENIC EXTRACELLULAR MPT63 MPB63 PRECURSOR IMMUNOPROTECTIVE SIGNAL SEQUENCING DIRECT 53 148 3.0E-17 T 06-07-2017 IPR015250 MPT63-like GO:0005615 CAK77_RS00215 93059c8691043b22b29e7b0cf3196b64 210 Gene3D G3DSA:2.60.40.1240 30 158 1.1E-48 T 06-07-2017 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain CAK77_RS08690 5d79aaac1d4d20ef9f85b3ac9634415e 226 Pfam PF00392 Bacterial regulatory proteins, gntR family 16 77 1.1E-17 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK77_RS08690 5d79aaac1d4d20ef9f85b3ac9634415e 226 Gene3D G3DSA:1.10.10.10 8 79 4.9E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS08690 5d79aaac1d4d20ef9f85b3ac9634415e 226 Gene3D G3DSA:1.20.120.530 81 206 2.4E-17 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAK77_RS08690 5d79aaac1d4d20ef9f85b3ac9634415e 226 SMART SM00345 19 77 7.4E-17 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK77_RS08690 5d79aaac1d4d20ef9f85b3ac9634415e 226 SMART SM00895 87 210 1.7E-8 T 06-07-2017 IPR011711 GntR, C-terminal CAK77_RS08690 5d79aaac1d4d20ef9f85b3ac9634415e 226 SUPERFAMILY SSF48008 95 209 1.36E-16 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAK77_RS08690 5d79aaac1d4d20ef9f85b3ac9634415e 226 Pfam PF07729 FCD domain 93 206 3.1E-20 T 06-07-2017 IPR011711 GntR, C-terminal CAK77_RS08690 5d79aaac1d4d20ef9f85b3ac9634415e 226 SUPERFAMILY SSF46785 15 81 8.47E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS11235 9fab7bd73f104fd4d39a9a43bce9430d 150 TIGRFAM TIGR01950 SoxR: redox-sensitive transcriptional activator SoxR 8 145 3.4E-49 T 06-07-2017 IPR010211 Redox-sensitive transcriptional activator SoxR GO:0003677|GO:0006355|GO:0006979|GO:0051537 CAK77_RS11235 9fab7bd73f104fd4d39a9a43bce9430d 150 SMART SM00422 8 76 7.5E-22 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAK77_RS11235 9fab7bd73f104fd4d39a9a43bce9430d 150 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 9 20 3.5E-6 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAK77_RS11235 9fab7bd73f104fd4d39a9a43bce9430d 150 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 43 63 3.5E-6 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAK77_RS11235 9fab7bd73f104fd4d39a9a43bce9430d 150 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 20 33 3.5E-6 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAK77_RS11235 9fab7bd73f104fd4d39a9a43bce9430d 150 Gene3D G3DSA:1.10.1660.10 63 140 7.6E-11 T 06-07-2017 CAK77_RS11235 9fab7bd73f104fd4d39a9a43bce9430d 150 SUPERFAMILY SSF46955 9 130 7.69E-25 T 06-07-2017 IPR009061 Putative DNA-binding domain CAK77_RS11235 9fab7bd73f104fd4d39a9a43bce9430d 150 Pfam PF13411 MerR HTH family regulatory protein 9 74 7.0E-13 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAK77_RS11235 9fab7bd73f104fd4d39a9a43bce9430d 150 Gene3D G3DSA:1.10.1660.10 6 62 3.5E-18 T 06-07-2017 CAK77_RS09580 4aa34bd5ab52ae7af1c9f84ee4c946fa 600 Gene3D G3DSA:3.30.420.10 23 202 5.8E-59 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAK77_RS09580 4aa34bd5ab52ae7af1c9f84ee4c946fa 600 SUPERFAMILY SSF82771 229 306 4.05E-15 T 06-07-2017 IPR000305 GIY-YIG nuclease superfamily CAK77_RS09580 4aa34bd5ab52ae7af1c9f84ee4c946fa 600 Pfam PF00929 Exonuclease 29 186 3.6E-36 T 06-07-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III CAK77_RS09580 4aa34bd5ab52ae7af1c9f84ee4c946fa 600 SUPERFAMILY SSF53098 23 206 3.0E-55 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAK77_RS09580 4aa34bd5ab52ae7af1c9f84ee4c946fa 600 SMART SM00465 228 309 6.4E-12 T 06-07-2017 IPR000305 GIY-YIG nuclease superfamily CAK77_RS09580 4aa34bd5ab52ae7af1c9f84ee4c946fa 600 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 22 197 8.9E-33 T 06-07-2017 IPR006054 DNA polymerase III, epsilon subunit GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAK77_RS09580 4aa34bd5ab52ae7af1c9f84ee4c946fa 600 SMART SM00479 27 195 9.8E-53 T 06-07-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III CAK77_RS09715 f02bcb3705c9a40911de4e0afe0eb8cc 331 Gene3D G3DSA:3.40.50.150 10 125 1.3E-39 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS09715 f02bcb3705c9a40911de4e0afe0eb8cc 331 Gene3D G3DSA:3.40.50.150 233 326 1.3E-39 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS09715 f02bcb3705c9a40911de4e0afe0eb8cc 331 SUPERFAMILY SSF53335 230 325 2.16E-38 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS09715 f02bcb3705c9a40911de4e0afe0eb8cc 331 SUPERFAMILY SSF53335 10 128 2.16E-38 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS09715 f02bcb3705c9a40911de4e0afe0eb8cc 331 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 35 324 1.1E-80 T 06-07-2017 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CAK77_RS09715 f02bcb3705c9a40911de4e0afe0eb8cc 331 Pfam PF01795 MraW methylase family 9 324 3.3E-105 T 06-07-2017 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CAK77_RS09715 f02bcb3705c9a40911de4e0afe0eb8cc 331 Gene3D G3DSA:1.10.150.170 127 232 5.1E-35 T 06-07-2017 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CAK77_RS09715 f02bcb3705c9a40911de4e0afe0eb8cc 331 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 10 325 34.774 T 06-07-2017 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CAK77_RS09715 f02bcb3705c9a40911de4e0afe0eb8cc 331 PIRSF PIRSF004486 4 326 2.0E-90 T 06-07-2017 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CAK77_RS09715 f02bcb3705c9a40911de4e0afe0eb8cc 331 SUPERFAMILY SSF81799 129 230 5.23E-32 T 06-07-2017 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CAK77_RS00325 9aaa7a83093d6650b3b9eaf0260e521f 628 SMART SM00220 11 274 1.0E-67 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CAK77_RS00325 9aaa7a83093d6650b3b9eaf0260e521f 628 SMART SM00740 422 490 9.5E-12 T 06-07-2017 IPR005543 PASTA domain CAK77_RS00325 9aaa7a83093d6650b3b9eaf0260e521f 628 SMART SM00740 355 421 2.9E-14 T 06-07-2017 IPR005543 PASTA domain CAK77_RS00325 9aaa7a83093d6650b3b9eaf0260e521f 628 SMART SM00740 491 558 1.5E-5 T 06-07-2017 IPR005543 PASTA domain CAK77_RS00325 9aaa7a83093d6650b3b9eaf0260e521f 628 SMART SM00740 559 627 0.53 T 06-07-2017 IPR005543 PASTA domain CAK77_RS00325 9aaa7a83093d6650b3b9eaf0260e521f 628 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 17 40 - T 06-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 CAK77_RS00325 9aaa7a83093d6650b3b9eaf0260e521f 628 Pfam PF00069 Protein kinase domain 11 264 7.7E-50 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CAK77_RS00325 9aaa7a83093d6650b3b9eaf0260e521f 628 Gene3D G3DSA:3.30.200.20 3 79 2.9E-30 T 06-07-2017 CAK77_RS00325 9aaa7a83093d6650b3b9eaf0260e521f 628 Pfam PF03793 PASTA domain 359 420 3.5E-16 T 06-07-2017 IPR005543 PASTA domain CAK77_RS00325 9aaa7a83093d6650b3b9eaf0260e521f 628 Pfam PF03793 PASTA domain 427 490 6.2E-8 T 06-07-2017 IPR005543 PASTA domain CAK77_RS00325 9aaa7a83093d6650b3b9eaf0260e521f 628 Pfam PF03793 PASTA domain 563 624 6.2E-6 T 06-07-2017 IPR005543 PASTA domain CAK77_RS00325 9aaa7a83093d6650b3b9eaf0260e521f 628 Pfam PF03793 PASTA domain 497 557 7.8E-8 T 06-07-2017 IPR005543 PASTA domain CAK77_RS00325 9aaa7a83093d6650b3b9eaf0260e521f 628 SUPERFAMILY SSF56112 8 287 5.26E-79 T 06-07-2017 IPR011009 Protein kinase-like domain CAK77_RS00325 9aaa7a83093d6650b3b9eaf0260e521f 628 Gene3D G3DSA:1.10.510.10 80 270 2.0E-54 T 06-07-2017 CAK77_RS00325 9aaa7a83093d6650b3b9eaf0260e521f 628 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 134 146 - T 06-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CAK77_RS24275 2955bdd4dd45a967627a053956f14607 478 SUPERFAMILY SSF81891 164 475 2.22E-64 T 06-07-2017 CAK77_RS24275 2955bdd4dd45a967627a053956f14607 478 SUPERFAMILY SSF81301 30 162 1.31E-34 T 06-07-2017 CAK77_RS24275 2955bdd4dd45a967627a053956f14607 478 Gene3D G3DSA:1.10.3090.10 164 352 8.5E-54 T 06-07-2017 CAK77_RS24275 2955bdd4dd45a967627a053956f14607 478 Gene3D G3DSA:1.10.3090.10 420 442 8.5E-54 T 06-07-2017 CAK77_RS24275 2955bdd4dd45a967627a053956f14607 478 Pfam PF01743 Poly A polymerase head domain 39 165 2.4E-32 T 06-07-2017 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 CAK77_RS24275 2955bdd4dd45a967627a053956f14607 478 Pfam PF01966 HD domain 268 388 1.6E-15 T 06-07-2017 IPR006674 HD domain CAK77_RS24275 2955bdd4dd45a967627a053956f14607 478 SMART SM00471 264 430 3.4E-5 T 06-07-2017 IPR003607 HD/PDEase domain CAK77_RS24275 2955bdd4dd45a967627a053956f14607 478 TIGRFAM TIGR00277 HDIG: HDIG domain 265 345 7.5E-20 T 06-07-2017 IPR006675 HDIG domain CAK77_RS24275 2955bdd4dd45a967627a053956f14607 478 TIGRFAM TIGR02692 tRNA_CCA_actino: CCA tRNA nucleotidyltransferase 11 475 5.5E-252 T 06-07-2017 IPR014065 tRNA adenylyltransferase CAK77_RS24275 2955bdd4dd45a967627a053956f14607 478 Gene3D G3DSA:3.30.460.10 19 162 6.8E-41 T 06-07-2017 CAK77_RS24275 2955bdd4dd45a967627a053956f14607 478 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 193 252 6.3E-17 T 06-07-2017 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 CAK77_RS01765 f9501362f964f65edec352c6982dc55d 116 PIRSF PIRSF021239 2 113 6.1E-47 T 06-07-2017 IPR007437 Putative member of DMT superfamily CAK77_RS01765 f9501362f964f65edec352c6982dc55d 116 SUPERFAMILY SSF103481 21 112 2.22E-5 T 06-07-2017 CAK77_RS01765 f9501362f964f65edec352c6982dc55d 116 Pfam PF04342 Putative member of DMT superfamily (DUF486) 10 110 8.8E-46 T 06-07-2017 IPR007437 Putative member of DMT superfamily CAK77_RS13775 cd568aa503b968714fca15bf9c31fa58 473 Gene3D G3DSA:2.30.40.10 4 76 3.4E-28 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK77_RS13775 cd568aa503b968714fca15bf9c31fa58 473 SUPERFAMILY SSF51338 3 80 2.43E-10 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK77_RS13775 cd568aa503b968714fca15bf9c31fa58 473 SUPERFAMILY SSF51338 363 467 2.75E-31 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK77_RS13775 cd568aa503b968714fca15bf9c31fa58 473 SUPERFAMILY SSF51556 62 393 1.76E-100 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK77_RS13775 cd568aa503b968714fca15bf9c31fa58 473 Pfam PF01979 Amidohydrolase family 58 447 2.3E-26 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAK77_RS13775 cd568aa503b968714fca15bf9c31fa58 473 TIGRFAM TIGR02033 D-hydantoinase: dihydropyrimidinase 5 466 1.9E-163 T 06-07-2017 IPR011778 Hydantoinase/dihydropyrimidinase GO:0005737 Reactome: R-HSA-399956 CAK77_RS13775 cd568aa503b968714fca15bf9c31fa58 473 Gene3D G3DSA:3.20.20.140 77 386 7.0E-111 T 06-07-2017 CAK77_RS13775 cd568aa503b968714fca15bf9c31fa58 473 Gene3D G3DSA:2.30.40.10 387 461 1.6E-9 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK77_RS08075 cde562e9e177b49e6f97540a89ddba47 490 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 157 217 3.0E-7 T 06-07-2017 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 CAK77_RS08075 cde562e9e177b49e6f97540a89ddba47 490 SUPERFAMILY SSF109998 246 428 1.28E-36 T 06-07-2017 IPR027304 Trigger factor/SurA domain CAK77_RS08075 cde562e9e177b49e6f97540a89ddba47 490 SUPERFAMILY SSF54534 133 243 2.27E-22 T 06-07-2017 CAK77_RS08075 cde562e9e177b49e6f97540a89ddba47 490 Gene3D G3DSA:1.10.3120.10 211 394 2.6E-41 T 06-07-2017 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 CAK77_RS08075 cde562e9e177b49e6f97540a89ddba47 490 TIGRFAM TIGR00115 tig: trigger factor 12 417 6.7E-117 T 06-07-2017 IPR005215 Trigger factor GO:0015031 CAK77_RS08075 cde562e9e177b49e6f97540a89ddba47 490 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 258 417 9.8E-35 T 06-07-2017 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 CAK77_RS08075 cde562e9e177b49e6f97540a89ddba47 490 PIRSF PIRSF003095 1 436 2.3E-115 T 06-07-2017 IPR005215 Trigger factor GO:0015031 CAK77_RS08075 cde562e9e177b49e6f97540a89ddba47 490 Pfam PF05697 Bacterial trigger factor protein (TF) 2 144 1.8E-41 T 06-07-2017 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 CAK77_RS08075 cde562e9e177b49e6f97540a89ddba47 490 Hamap MF_00303 Trigger factor [tig]. 1 424 18.953 T 06-07-2017 IPR005215 Trigger factor GO:0015031 CAK77_RS08075 cde562e9e177b49e6f97540a89ddba47 490 Gene3D G3DSA:3.30.70.1050 2 119 3.3E-35 T 06-07-2017 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 CAK77_RS08075 cde562e9e177b49e6f97540a89ddba47 490 Gene3D G3DSA:3.10.50.40 154 210 7.4E-8 T 06-07-2017 CAK77_RS08075 cde562e9e177b49e6f97540a89ddba47 490 SUPERFAMILY SSF102735 2 129 3.92E-36 T 06-07-2017 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 CAK77_RS23275 78f4002fecf1c312689ec5c5a30c0dc2 521 SUPERFAMILY SSF52096 271 512 1.67E-59 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS23275 78f4002fecf1c312689ec5c5a30c0dc2 521 Gene3D G3DSA:3.90.226.10 22 262 4.8E-41 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS23275 78f4002fecf1c312689ec5c5a30c0dc2 521 SUPERFAMILY SSF52096 12 262 1.43E-48 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS23275 78f4002fecf1c312689ec5c5a30c0dc2 521 Gene3D G3DSA:3.90.226.10 272 512 4.3E-54 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS23275 78f4002fecf1c312689ec5c5a30c0dc2 521 Pfam PF01039 Carboxyl transferase domain 32 510 5.4E-75 T 06-07-2017 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAK77_RS12015 9fa8cd02db68ac5543b62ab6d9fc2c38 237 Pfam PF13302 Acetyltransferase (GNAT) domain 100 200 2.9E-6 T 06-07-2017 IPR000182 GNAT domain GO:0008080 CAK77_RS12015 9fa8cd02db68ac5543b62ab6d9fc2c38 237 SUPERFAMILY SSF55729 90 199 4.29E-12 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS12015 9fa8cd02db68ac5543b62ab6d9fc2c38 237 Gene3D G3DSA:3.40.630.30 98 197 1.8E-12 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS10450 970984b50d236736bc27eef6265a1ccc 221 Pfam PF02405 Permease MlaE 98 220 1.4E-15 T 06-07-2017 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 CAK77_RS24325 4c157f9eee7597b391dadafd438bd01e 531 Pfam PF00067 Cytochrome P450 90 516 1.3E-72 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS24325 4c157f9eee7597b391dadafd438bd01e 531 PRINTS PR00463 E-class P450 group I signature 333 350 1.9E-26 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS24325 4c157f9eee7597b391dadafd438bd01e 531 PRINTS PR00463 E-class P450 group I signature 117 136 1.9E-26 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS24325 4c157f9eee7597b391dadafd438bd01e 531 PRINTS PR00463 E-class P450 group I signature 353 379 1.9E-26 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS24325 4c157f9eee7597b391dadafd438bd01e 531 PRINTS PR00463 E-class P450 group I signature 479 502 1.9E-26 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS24325 4c157f9eee7597b391dadafd438bd01e 531 PRINTS PR00463 E-class P450 group I signature 433 457 1.9E-26 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS24325 4c157f9eee7597b391dadafd438bd01e 531 PRINTS PR00463 E-class P450 group I signature 469 479 1.9E-26 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS24325 4c157f9eee7597b391dadafd438bd01e 531 SUPERFAMILY SSF48264 89 529 2.75E-100 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS24325 4c157f9eee7597b391dadafd438bd01e 531 Gene3D G3DSA:1.10.630.10 90 529 1.8E-104 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS24325 4c157f9eee7597b391dadafd438bd01e 531 PRINTS PR00385 P450 superfamily signature 479 490 3.0E-6 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS24325 4c157f9eee7597b391dadafd438bd01e 531 PRINTS PR00385 P450 superfamily signature 344 361 3.0E-6 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS24325 4c157f9eee7597b391dadafd438bd01e 531 PRINTS PR00385 P450 superfamily signature 470 479 3.0E-6 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS24325 4c157f9eee7597b391dadafd438bd01e 531 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 472 481 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CAK77_RS16400 bd58c600fdc3fb7bb0bceb2d1d43e5a2 480 Gene3D G3DSA:3.30.499.10 3 162 2.0E-24 T 06-07-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CAK77_RS16400 bd58c600fdc3fb7bb0bceb2d1d43e5a2 480 PRINTS PR00415 Aconitase family signature 143 158 1.4E-47 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAK77_RS16400 bd58c600fdc3fb7bb0bceb2d1d43e5a2 480 PRINTS PR00415 Aconitase family signature 409 422 1.4E-47 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAK77_RS16400 bd58c600fdc3fb7bb0bceb2d1d43e5a2 480 PRINTS PR00415 Aconitase family signature 118 126 1.4E-47 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAK77_RS16400 bd58c600fdc3fb7bb0bceb2d1d43e5a2 480 PRINTS PR00415 Aconitase family signature 296 310 1.4E-47 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAK77_RS16400 bd58c600fdc3fb7bb0bceb2d1d43e5a2 480 PRINTS PR00415 Aconitase family signature 92 105 1.4E-47 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAK77_RS16400 bd58c600fdc3fb7bb0bceb2d1d43e5a2 480 PRINTS PR00415 Aconitase family signature 353 364 1.4E-47 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAK77_RS16400 bd58c600fdc3fb7bb0bceb2d1d43e5a2 480 PRINTS PR00415 Aconitase family signature 129 142 1.4E-47 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAK77_RS16400 bd58c600fdc3fb7bb0bceb2d1d43e5a2 480 PRINTS PR00415 Aconitase family signature 205 218 1.4E-47 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAK77_RS16400 bd58c600fdc3fb7bb0bceb2d1d43e5a2 480 PRINTS PR00415 Aconitase family signature 219 232 1.4E-47 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAK77_RS16400 bd58c600fdc3fb7bb0bceb2d1d43e5a2 480 Pfam PF00330 Aconitase family (aconitate hydratase) 12 467 1.7E-150 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAK77_RS16400 bd58c600fdc3fb7bb0bceb2d1d43e5a2 480 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 7 469 2.4E-219 T 06-07-2017 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 CAK77_RS16400 bd58c600fdc3fb7bb0bceb2d1d43e5a2 480 SUPERFAMILY SSF53732 6 475 7.19E-158 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAK77_RS16400 bd58c600fdc3fb7bb0bceb2d1d43e5a2 480 Gene3D G3DSA:3.40.1060.10 163 298 1.2E-38 T 06-07-2017 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 CAK77_RS16400 bd58c600fdc3fb7bb0bceb2d1d43e5a2 480 ProSitePatterns PS00450 Aconitase family signature 1. 349 365 - T 06-07-2017 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CAK77_RS16400 bd58c600fdc3fb7bb0bceb2d1d43e5a2 480 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 6 476 59.075 T 06-07-2017 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 CAK77_RS16400 bd58c600fdc3fb7bb0bceb2d1d43e5a2 480 ProSitePatterns PS01244 Aconitase family signature 2. 409 422 - T 06-07-2017 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CAK77_RS16400 bd58c600fdc3fb7bb0bceb2d1d43e5a2 480 Gene3D G3DSA:3.30.499.10 338 476 5.2E-58 T 06-07-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CAK77_RS05590 10e7592a9c667274bac5dada8e20ea65 523 Hamap MF_01228 Methionine--tRNA ligase [metG]. 1 520 46.993 T 06-07-2017 IPR023457 Methionine-tRNA synthetase, type 2 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CAK77_RS05590 10e7592a9c667274bac5dada8e20ea65 523 Gene3D G3DSA:1.10.730.10 344 518 7.4E-51 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK77_RS05590 10e7592a9c667274bac5dada8e20ea65 523 Pfam PF09334 tRNA synthetases class I (M) 8 367 9.8E-110 T 06-07-2017 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK77_RS05590 10e7592a9c667274bac5dada8e20ea65 523 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 8 496 9.2E-148 T 06-07-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CAK77_RS05590 10e7592a9c667274bac5dada8e20ea65 523 PRINTS PR01041 Methionyl-tRNA synthetase signature 263 278 2.3E-34 T 06-07-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CAK77_RS05590 10e7592a9c667274bac5dada8e20ea65 523 PRINTS PR01041 Methionyl-tRNA synthetase signature 355 366 2.3E-34 T 06-07-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CAK77_RS05590 10e7592a9c667274bac5dada8e20ea65 523 PRINTS PR01041 Methionyl-tRNA synthetase signature 42 56 2.3E-34 T 06-07-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CAK77_RS05590 10e7592a9c667274bac5dada8e20ea65 523 PRINTS PR01041 Methionyl-tRNA synthetase signature 230 241 2.3E-34 T 06-07-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CAK77_RS05590 10e7592a9c667274bac5dada8e20ea65 523 PRINTS PR01041 Methionyl-tRNA synthetase signature 10 23 2.3E-34 T 06-07-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CAK77_RS05590 10e7592a9c667274bac5dada8e20ea65 523 PRINTS PR01041 Methionyl-tRNA synthetase signature 90 101 2.3E-34 T 06-07-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CAK77_RS05590 10e7592a9c667274bac5dada8e20ea65 523 Gene3D G3DSA:2.170.220.10 119 231 6.9E-45 T 06-07-2017 CAK77_RS05590 10e7592a9c667274bac5dada8e20ea65 523 Gene3D G3DSA:3.40.50.620 7 116 1.6E-73 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS05590 10e7592a9c667274bac5dada8e20ea65 523 Gene3D G3DSA:3.40.50.620 232 341 1.6E-73 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS05590 10e7592a9c667274bac5dada8e20ea65 523 SUPERFAMILY SSF52374 7 358 5.63E-111 T 06-07-2017 CAK77_RS05590 10e7592a9c667274bac5dada8e20ea65 523 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 17 26 - T 06-07-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK77_RS05590 10e7592a9c667274bac5dada8e20ea65 523 SUPERFAMILY SSF47323 356 518 2.24E-35 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK77_RS18240 15eea57a7b2d89ee41c865490fc757e9 213 SUPERFAMILY SSF53271 3 211 1.08E-55 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like CAK77_RS18240 15eea57a7b2d89ee41c865490fc757e9 213 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 2 213 39.392 T 06-07-2017 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 CAK77_RS18240 15eea57a7b2d89ee41c865490fc757e9 213 Gene3D G3DSA:3.40.50.2020 2 211 4.9E-68 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like CAK77_RS18240 15eea57a7b2d89ee41c865490fc757e9 213 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 3 212 2.9E-72 T 06-07-2017 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 CAK77_RS18240 15eea57a7b2d89ee41c865490fc757e9 213 Pfam PF14681 Uracil phosphoribosyltransferase 5 211 5.5E-59 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like CAK77_RS03805 a9def1b10118c88a2827f300c9daec5f 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 1.2E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS03805 a9def1b10118c88a2827f300c9daec5f 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 1.2E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS03805 a9def1b10118c88a2827f300c9daec5f 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 1.2E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS03805 a9def1b10118c88a2827f300c9daec5f 248 SUPERFAMILY SSF51735 9 247 1.58E-80 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS03805 a9def1b10118c88a2827f300c9daec5f 248 Gene3D G3DSA:3.40.50.720 4 247 7.5E-85 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS03805 a9def1b10118c88a2827f300c9daec5f 248 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 245 2.1E-60 T 06-07-2017 CAK77_RS03805 a9def1b10118c88a2827f300c9daec5f 248 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 187 3.8E-4 T 06-07-2017 CAK77_RS03805 a9def1b10118c88a2827f300c9daec5f 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 1.0E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS03805 a9def1b10118c88a2827f300c9daec5f 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 1.0E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS03805 a9def1b10118c88a2827f300c9daec5f 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 1.0E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS03805 a9def1b10118c88a2827f300c9daec5f 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.0E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS03805 a9def1b10118c88a2827f300c9daec5f 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 1.0E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS03805 a9def1b10118c88a2827f300c9daec5f 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 1.0E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS01065 6baa29ca585fe39c7768da0ce381e459 1784 SMART SM00825 Beta-ketoacyl synthase 131 556 8.4E-182 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAK77_RS01065 6baa29ca585fe39c7768da0ce381e459 1784 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 506 554 3.6E-10 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAK77_RS01065 6baa29ca585fe39c7768da0ce381e459 1784 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 734 1038 4.3E-72 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain CAK77_RS01065 6baa29ca585fe39c7768da0ce381e459 1784 SUPERFAMILY SSF47336 31 108 1.06E-15 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS01065 6baa29ca585fe39c7768da0ce381e459 1784 Gene3D G3DSA:3.30.70.250 864 922 6.4E-4 T 06-07-2017 CAK77_RS01065 6baa29ca585fe39c7768da0ce381e459 1784 Pfam PF00698 Acyl transferase domain 732 1055 6.0E-49 T 06-07-2017 IPR014043 Acyl transferase CAK77_RS01065 6baa29ca585fe39c7768da0ce381e459 1784 Pfam PF00550 Phosphopantetheine attachment site 37 103 2.5E-12 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS01065 6baa29ca585fe39c7768da0ce381e459 1784 Pfam PF00550 Phosphopantetheine attachment site 1262 1313 6.9E-5 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS01065 6baa29ca585fe39c7768da0ce381e459 1784 SMART SM00823 Phosphopantetheine attachment site 36 107 1.6E-9 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAK77_RS01065 6baa29ca585fe39c7768da0ce381e459 1784 SMART SM00823 Phosphopantetheine attachment site 1261 1316 4.0E-4 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAK77_RS01065 6baa29ca585fe39c7768da0ce381e459 1784 SUPERFAMILY SSF53901 531 552 1.15E-92 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS01065 6baa29ca585fe39c7768da0ce381e459 1784 SUPERFAMILY SSF53901 129 499 1.15E-92 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS01065 6baa29ca585fe39c7768da0ce381e459 1784 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 386 503 2.6E-41 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAK77_RS01065 6baa29ca585fe39c7768da0ce381e459 1784 SUPERFAMILY SSF52151 732 856 9.68E-43 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAK77_RS01065 6baa29ca585fe39c7768da0ce381e459 1784 SUPERFAMILY SSF52151 925 1013 9.68E-43 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAK77_RS01065 6baa29ca585fe39c7768da0ce381e459 1784 SUPERFAMILY SSF55048 864 922 4.97E-7 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CAK77_RS01065 6baa29ca585fe39c7768da0ce381e459 1784 Gene3D G3DSA:3.40.50.1820 1513 1618 3.4E-30 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS01065 6baa29ca585fe39c7768da0ce381e459 1784 Gene3D G3DSA:3.40.50.1820 1704 1773 3.4E-30 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS01065 6baa29ca585fe39c7768da0ce381e459 1784 SUPERFAMILY SSF53474 1514 1773 3.77E-42 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS01065 6baa29ca585fe39c7768da0ce381e459 1784 Pfam PF00975 Thioesterase domain 1525 1631 3.1E-14 T 06-07-2017 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 CAK77_RS01065 6baa29ca585fe39c7768da0ce381e459 1784 SMART SM01294 37 103 0.004 T 06-07-2017 CAK77_RS01065 6baa29ca585fe39c7768da0ce381e459 1784 SUPERFAMILY SSF47336 1256 1312 4.19E-9 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS01065 6baa29ca585fe39c7768da0ce381e459 1784 Gene3D G3DSA:3.40.47.10 391 554 1.5E-56 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS01065 6baa29ca585fe39c7768da0ce381e459 1784 Gene3D G3DSA:1.10.1200.10 34 103 6.0E-14 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS01065 6baa29ca585fe39c7768da0ce381e459 1784 Gene3D G3DSA:3.40.47.10 131 390 2.7E-92 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS01065 6baa29ca585fe39c7768da0ce381e459 1784 Gene3D G3DSA:3.40.366.10 730 851 2.0E-49 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAK77_RS01065 6baa29ca585fe39c7768da0ce381e459 1784 Gene3D G3DSA:3.40.366.10 924 1052 2.0E-49 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAK77_RS01065 6baa29ca585fe39c7768da0ce381e459 1784 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 130 378 6.2E-83 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAK77_RS01065 6baa29ca585fe39c7768da0ce381e459 1784 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 290 306 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site CAK77_RS01065 6baa29ca585fe39c7768da0ce381e459 1784 Gene3D G3DSA:1.10.1200.10 1255 1314 1.3E-7 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS03870 41ef472aa66665a5ccff9b0f687eb879 402 Gene3D G3DSA:1.10.260.40 36 104 1.7E-13 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK77_RS03870 41ef472aa66665a5ccff9b0f687eb879 402 SUPERFAMILY SSF47413 36 103 3.38E-10 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK77_RS03870 41ef472aa66665a5ccff9b0f687eb879 402 Pfam PF06114 Domain of unknown function (DUF955) 188 302 1.7E-7 T 06-07-2017 IPR010359 HTH domain, IrrE-type CAK77_RS03870 41ef472aa66665a5ccff9b0f687eb879 402 Pfam PF01381 Helix-turn-helix 47 99 1.4E-7 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAK77_RS03870 41ef472aa66665a5ccff9b0f687eb879 402 SMART SM00530 45 100 2.2E-8 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAK77_RS22000 a8a6518924e19868f74bd46ae708a5eb 228 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 53 69 3.3E-5 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK77_RS22000 a8a6518924e19868f74bd46ae708a5eb 228 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 39 53 3.3E-5 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK77_RS22000 a8a6518924e19868f74bd46ae708a5eb 228 SUPERFAMILY SSF48008 85 220 8.37E-25 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAK77_RS22000 a8a6518924e19868f74bd46ae708a5eb 228 SUPERFAMILY SSF46785 12 83 5.46E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS22000 a8a6518924e19868f74bd46ae708a5eb 228 Gene3D G3DSA:1.10.10.10 7 79 1.0E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS22000 a8a6518924e19868f74bd46ae708a5eb 228 Gene3D G3DSA:1.20.120.530 83 221 5.3E-27 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAK77_RS22000 a8a6518924e19868f74bd46ae708a5eb 228 Pfam PF00392 Bacterial regulatory proteins, gntR family 18 79 1.8E-19 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK77_RS22000 a8a6518924e19868f74bd46ae708a5eb 228 SMART SM00345 21 79 3.4E-19 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK77_RS22000 a8a6518924e19868f74bd46ae708a5eb 228 Pfam PF07729 FCD domain 89 212 1.4E-20 T 06-07-2017 IPR011711 GntR, C-terminal CAK77_RS22000 a8a6518924e19868f74bd46ae708a5eb 228 SMART SM00895 89 213 7.6E-13 T 06-07-2017 IPR011711 GntR, C-terminal CAK77_RS19085 7e3e009c671c948aa86b2187c2896438 156 SUPERFAMILY SSF54637 17 153 3.85E-21 T 06-07-2017 IPR029069 HotDog domain CAK77_RS19085 7e3e009c671c948aa86b2187c2896438 156 Gene3D G3DSA:3.10.129.10 7 155 9.8E-55 T 06-07-2017 IPR029069 HotDog domain CAK77_RS19085 7e3e009c671c948aa86b2187c2896438 156 Pfam PF14539 Domain of unknown function (DUF4442) 19 153 5.6E-55 T 06-07-2017 IPR027961 Protein of unknown function DUF4442 CAK77_RS21185 181118d0e15016e1015efcfa55831990 997 SUPERFAMILY SSF88713 249 515 7.12E-80 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CAK77_RS21185 181118d0e15016e1015efcfa55831990 997 Pfam PF09261 Alpha mannosidase middle domain 517 595 9.4E-29 T 06-07-2017 IPR015341 Glycoside hydrolase family 38, central domain GO:0004553|GO:0008270 CAK77_RS21185 181118d0e15016e1015efcfa55831990 997 SMART SM00872 517 595 5.5E-41 T 06-07-2017 IPR015341 Glycoside hydrolase family 38, central domain GO:0004553|GO:0008270 CAK77_RS21185 181118d0e15016e1015efcfa55831990 997 Pfam PF07748 Glycosyl hydrolases family 38 C-terminal domain 654 989 1.6E-55 T 06-07-2017 IPR011682 Glycosyl hydrolase family 38, C-terminal GO:0006013|GO:0015923 CAK77_RS21185 181118d0e15016e1015efcfa55831990 997 SUPERFAMILY SSF88688 516 618 6.87E-29 T 06-07-2017 IPR028995 Glycoside hydrolase families 57/38, central domain CAK77_RS21185 181118d0e15016e1015efcfa55831990 997 Gene3D G3DSA:1.20.1270.50 520 617 7.8E-26 T 06-07-2017 IPR015341 Glycoside hydrolase family 38, central domain GO:0004553|GO:0008270 CAK77_RS21185 181118d0e15016e1015efcfa55831990 997 SUPERFAMILY SSF74650 628 990 4.08E-58 T 06-07-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CAK77_RS21185 181118d0e15016e1015efcfa55831990 997 Gene3D G3DSA:3.20.110.10 204 519 3.6E-92 T 06-07-2017 IPR027291 Glycoside hydrolase 38/57, N-terminal domain CAK77_RS21185 181118d0e15016e1015efcfa55831990 997 Pfam PF01074 Glycosyl hydrolases family 38 N-terminal domain 253 504 2.0E-86 T 06-07-2017 IPR000602 Glycoside hydrolase family 38, N-terminal domain GO:0004559|GO:0005975 CAK77_RS00885 ffdeea4fd87691421835a5ea60dbcc51 290 SUPERFAMILY SSF51735 3 260 2.99E-59 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS00885 ffdeea4fd87691421835a5ea60dbcc51 290 Gene3D G3DSA:3.40.50.720 3 228 2.8E-59 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS00885 ffdeea4fd87691421835a5ea60dbcc51 290 Pfam PF00106 short chain dehydrogenase 3 191 1.6E-47 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS00885 ffdeea4fd87691421835a5ea60dbcc51 290 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 7.4E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS00885 ffdeea4fd87691421835a5ea60dbcc51 290 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 7.4E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS00885 ffdeea4fd87691421835a5ea60dbcc51 290 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 170 7.4E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS00885 ffdeea4fd87691421835a5ea60dbcc51 290 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 7.5E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS00885 ffdeea4fd87691421835a5ea60dbcc51 290 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 7.5E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS00885 ffdeea4fd87691421835a5ea60dbcc51 290 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 7.5E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS00885 ffdeea4fd87691421835a5ea60dbcc51 290 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 7.5E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS00885 ffdeea4fd87691421835a5ea60dbcc51 290 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 7.5E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS19105 ff3c6e212396b7f3f285cae35fbba2c3 467 PIRSF PIRSF018788 2 466 1.4E-223 T 06-07-2017 IPR010628 Ethanolamine ammonia lyase large subunit GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 CAK77_RS19105 ff3c6e212396b7f3f285cae35fbba2c3 467 Gene3D G3DSA:3.20.20.70 149 453 6.6E-152 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK77_RS19105 ff3c6e212396b7f3f285cae35fbba2c3 467 Gene3D G3DSA:2.30.170.30 4 55 1.4E-22 T 06-07-2017 CAK77_RS19105 ff3c6e212396b7f3f285cae35fbba2c3 467 Gene3D G3DSA:1.10.220.70 56 143 4.7E-36 T 06-07-2017 CAK77_RS19105 ff3c6e212396b7f3f285cae35fbba2c3 467 Pfam PF06751 Ethanolamine ammonia lyase large subunit (EutB) 13 454 6.7E-209 T 06-07-2017 IPR010628 Ethanolamine ammonia lyase large subunit GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 CAK77_RS10055 bcceb10b9bdff8022b79c25ddd840cfc 284 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 153 181 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK77_RS10055 bcceb10b9bdff8022b79c25ddd840cfc 284 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 92 103 3.1E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS10055 bcceb10b9bdff8022b79c25ddd840cfc 284 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 187 204 3.1E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS10055 bcceb10b9bdff8022b79c25ddd840cfc 284 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 17 34 3.1E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS10055 bcceb10b9bdff8022b79c25ddd840cfc 284 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 185 3.1E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS10055 bcceb10b9bdff8022b79c25ddd840cfc 284 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 156 3.1E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS10055 bcceb10b9bdff8022b79c25ddd840cfc 284 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 92 103 1.6E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS10055 bcceb10b9bdff8022b79c25ddd840cfc 284 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 166 185 1.6E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS10055 bcceb10b9bdff8022b79c25ddd840cfc 284 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 154 1.6E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS10055 bcceb10b9bdff8022b79c25ddd840cfc 284 Gene3D G3DSA:3.40.50.720 18 261 7.7E-56 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS10055 bcceb10b9bdff8022b79c25ddd840cfc 284 Pfam PF00106 short chain dehydrogenase 18 206 4.8E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS10055 bcceb10b9bdff8022b79c25ddd840cfc 284 SUPERFAMILY SSF51735 18 270 1.07E-56 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS04535 85bcea12b64ceed241e57526e2b5dfba 334 Gene3D G3DSA:3.40.50.1820 24 168 1.8E-35 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS04535 85bcea12b64ceed241e57526e2b5dfba 334 Gene3D G3DSA:3.40.50.1820 239 293 1.8E-35 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS04535 85bcea12b64ceed241e57526e2b5dfba 334 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 75 286 1.2E-15 T 06-07-2017 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 CAK77_RS04535 85bcea12b64ceed241e57526e2b5dfba 334 SUPERFAMILY SSF53474 201 307 1.49E-40 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS04535 85bcea12b64ceed241e57526e2b5dfba 334 SUPERFAMILY SSF53474 27 172 1.49E-40 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS21650 f28cabc8f2df1459e0e84f00ac7db2ae 431 SUPERFAMILY SSF51445 40 339 1.17E-71 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily CAK77_RS21650 f28cabc8f2df1459e0e84f00ac7db2ae 431 Gene3D G3DSA:2.60.40.1180 334 427 3.9E-19 T 06-07-2017 IPR013780 Glycosyl hydrolase, all-beta CAK77_RS21650 f28cabc8f2df1459e0e84f00ac7db2ae 431 Pfam PF16499 Alpha galactosidase A 44 405 1.1E-69 T 06-07-2017 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CAK77_RS21650 f28cabc8f2df1459e0e84f00ac7db2ae 431 PRINTS PR00740 Glycosyl hydrolase family 27 signature 39 58 1.2E-33 T 06-07-2017 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CAK77_RS21650 f28cabc8f2df1459e0e84f00ac7db2ae 431 PRINTS PR00740 Glycosyl hydrolase family 27 signature 75 90 1.2E-33 T 06-07-2017 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CAK77_RS21650 f28cabc8f2df1459e0e84f00ac7db2ae 431 PRINTS PR00740 Glycosyl hydrolase family 27 signature 186 204 1.2E-33 T 06-07-2017 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CAK77_RS21650 f28cabc8f2df1459e0e84f00ac7db2ae 431 PRINTS PR00740 Glycosyl hydrolase family 27 signature 295 316 1.2E-33 T 06-07-2017 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CAK77_RS21650 f28cabc8f2df1459e0e84f00ac7db2ae 431 PRINTS PR00740 Glycosyl hydrolase family 27 signature 157 174 1.2E-33 T 06-07-2017 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CAK77_RS21650 f28cabc8f2df1459e0e84f00ac7db2ae 431 ProSitePatterns PS00512 Alpha-galactosidase signature. 80 96 - T 06-07-2017 IPR000111 Glycoside hydrolase family 27/36, conserved site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CAK77_RS21650 f28cabc8f2df1459e0e84f00ac7db2ae 431 Gene3D G3DSA:3.20.20.70 40 333 1.9E-93 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK77_RS21650 f28cabc8f2df1459e0e84f00ac7db2ae 431 SUPERFAMILY SSF51011 352 426 5.9E-10 T 06-07-2017 CAK77_RS11630 2e71faeb50e7ad133110f2aefa055fe2 428 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 273 422 2.1E-43 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS11630 2e71faeb50e7ad133110f2aefa055fe2 428 Gene3D G3DSA:2.40.110.10 152 256 3.4E-31 T 06-07-2017 CAK77_RS11630 2e71faeb50e7ad133110f2aefa055fe2 428 SUPERFAMILY SSF47203 272 424 3.38E-41 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS11630 2e71faeb50e7ad133110f2aefa055fe2 428 Gene3D G3DSA:1.10.540.10 1 56 6.5E-30 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS11630 2e71faeb50e7ad133110f2aefa055fe2 428 Gene3D G3DSA:1.10.540.10 89 150 6.5E-30 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS11630 2e71faeb50e7ad133110f2aefa055fe2 428 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 155 167 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CAK77_RS11630 2e71faeb50e7ad133110f2aefa055fe2 428 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 153 256 1.9E-21 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAK77_RS11630 2e71faeb50e7ad133110f2aefa055fe2 428 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 10 147 1.4E-11 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS11630 2e71faeb50e7ad133110f2aefa055fe2 428 SUPERFAMILY SSF56645 90 267 4.45E-48 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK77_RS11630 2e71faeb50e7ad133110f2aefa055fe2 428 Gene3D G3DSA:1.20.140.10 257 425 1.3E-47 T 06-07-2017 CAK77_RS03335 1ae20b070d5f036429ee43a6133ba9d5 304 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 196 5.7E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS03335 1ae20b070d5f036429ee43a6133ba9d5 304 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 17 34 5.7E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS03335 1ae20b070d5f036429ee43a6133ba9d5 304 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 93 104 5.7E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS03335 1ae20b070d5f036429ee43a6133ba9d5 304 Gene3D G3DSA:3.40.50.720 14 251 2.6E-53 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS03335 1ae20b070d5f036429ee43a6133ba9d5 304 SUPERFAMILY SSF51735 14 252 1.69E-49 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS03335 1ae20b070d5f036429ee43a6133ba9d5 304 Pfam PF00106 short chain dehydrogenase 17 218 4.1E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS09080 271ad1801e2d49ab600cbed10858734e 153 Gene3D G3DSA:3.40.30.10 1 151 8.1E-44 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK77_RS09080 271ad1801e2d49ab600cbed10858734e 153 Pfam PF00578 AhpC/TSA family 4 129 1.7E-33 T 06-07-2017 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CAK77_RS09080 271ad1801e2d49ab600cbed10858734e 153 PIRSF PIRSF000239 1 153 7.7E-27 T 06-07-2017 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CAK77_RS09080 271ad1801e2d49ab600cbed10858734e 153 SUPERFAMILY SSF52833 1 151 3.98E-40 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK77_RS00020 f2008a0fdc678c1d867ecf47df222181 297 SUPERFAMILY SSF51735 1 146 1.64E-39 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS00020 f2008a0fdc678c1d867ecf47df222181 297 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 142 1.1E-32 T 06-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CAK77_RS00020 f2008a0fdc678c1d867ecf47df222181 297 SMART SM01350 162 296 7.8E-5 T 06-07-2017 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CAK77_RS00020 f2008a0fdc678c1d867ecf47df222181 297 Gene3D G3DSA:1.10.1040.10 164 272 7.1E-34 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAK77_RS00020 f2008a0fdc678c1d867ecf47df222181 297 ProSitePatterns PS00461 6-phosphogluconate dehydrogenase signature. 230 242 - T 06-07-2017 IPR006184 6-phosphogluconate-binding site GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CAK77_RS00020 f2008a0fdc678c1d867ecf47df222181 297 TIGRFAM TIGR00872 gnd_rel: 6-phosphogluconate dehydrogenase (decarboxylating) 1 292 1.4E-102 T 06-07-2017 IPR004849 6-phosphogluconate dehydrogenase, YqeC-type GO:0055114 CAK77_RS00020 f2008a0fdc678c1d867ecf47df222181 297 SUPERFAMILY SSF48179 160 295 2.18E-40 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAK77_RS00020 f2008a0fdc678c1d867ecf47df222181 297 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 50 79 1.0E-32 T 06-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CAK77_RS00020 f2008a0fdc678c1d867ecf47df222181 297 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 1 15 1.0E-32 T 06-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CAK77_RS00020 f2008a0fdc678c1d867ecf47df222181 297 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 226 253 1.0E-32 T 06-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CAK77_RS00020 f2008a0fdc678c1d867ecf47df222181 297 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 151 179 1.0E-32 T 06-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CAK77_RS00020 f2008a0fdc678c1d867ecf47df222181 297 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 103 128 1.0E-32 T 06-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CAK77_RS00020 f2008a0fdc678c1d867ecf47df222181 297 Gene3D G3DSA:3.40.50.720 1 163 9.4E-39 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS00020 f2008a0fdc678c1d867ecf47df222181 297 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 162 272 5.5E-24 T 06-07-2017 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CAK77_RS01205 c95a5c9f4c739f00cc6c73b813a3db21 167 Gene3D G3DSA:1.10.10.10 7 155 3.1E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS01205 c95a5c9f4c739f00cc6c73b813a3db21 167 Pfam PF12802 MarR family 44 103 2.5E-11 T 06-07-2017 CAK77_RS01205 c95a5c9f4c739f00cc6c73b813a3db21 167 PRINTS PR00598 Bacterial regulatory protein MarR family signature 99 115 6.2E-5 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK77_RS01205 c95a5c9f4c739f00cc6c73b813a3db21 167 PRINTS PR00598 Bacterial regulatory protein MarR family signature 80 95 6.2E-5 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK77_RS01205 c95a5c9f4c739f00cc6c73b813a3db21 167 SUPERFAMILY SSF46785 12 152 5.75E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS01205 c95a5c9f4c739f00cc6c73b813a3db21 167 SMART SM00347 37 140 1.0E-12 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK77_RS07010 92b14eaf6de9e3ec32a33bb2891daa05 195 SUPERFAMILY SSF48498 74 193 2.05E-21 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS07010 92b14eaf6de9e3ec32a33bb2891daa05 195 Gene3D G3DSA:1.10.357.10 49 195 1.8E-43 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS07010 92b14eaf6de9e3ec32a33bb2891daa05 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 57 4.8E-12 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS07010 92b14eaf6de9e3ec32a33bb2891daa05 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 4.5E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS07010 92b14eaf6de9e3ec32a33bb2891daa05 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 4.5E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS07010 92b14eaf6de9e3ec32a33bb2891daa05 195 Pfam PF09209 Domain of unknown function (DUF1956) 77 194 2.0E-22 T 06-07-2017 IPR015292 Transcription regulator YbiH, C-terminal CAK77_RS07010 92b14eaf6de9e3ec32a33bb2891daa05 195 SUPERFAMILY SSF46689 4 68 9.75E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS07010 92b14eaf6de9e3ec32a33bb2891daa05 195 Gene3D G3DSA:1.10.10.60 4 48 2.2E-19 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS16075 9eeca4ac4100d3e645266678810ecebb 135 Pfam PF03061 Thioesterase superfamily 48 125 1.1E-11 T 06-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 CAK77_RS16075 9eeca4ac4100d3e645266678810ecebb 135 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 17 131 1.5E-22 T 06-07-2017 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-75105 CAK77_RS16075 9eeca4ac4100d3e645266678810ecebb 135 SUPERFAMILY SSF54637 3 132 9.39E-31 T 06-07-2017 IPR029069 HotDog domain CAK77_RS16075 9eeca4ac4100d3e645266678810ecebb 135 Gene3D G3DSA:3.10.129.10 8 132 1.7E-34 T 06-07-2017 IPR029069 HotDog domain CAK77_RS22815 d95267ad5d4d4bed24769d87ed0daed6 308 Pfam PF04072 Leucine carboxyl methyltransferase 27 203 1.9E-57 T 06-07-2017 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 CAK77_RS22815 d95267ad5d4d4bed24769d87ed0daed6 308 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 26 282 2.0E-83 T 06-07-2017 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 CAK77_RS22815 d95267ad5d4d4bed24769d87ed0daed6 308 SUPERFAMILY SSF53335 23 295 1.74E-70 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS22815 d95267ad5d4d4bed24769d87ed0daed6 308 Gene3D G3DSA:3.40.50.150 26 247 1.3E-18 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS18435 205a7de499e89e20e1bd2ad6775c01a8 1078 Hamap MF_01902 Error-prone DNA polymerase [dnaE2]. 42 1078 12.621 T 06-07-2017 IPR023073 DNA polymerase, error-prone GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAK77_RS18435 205a7de499e89e20e1bd2ad6775c01a8 1078 Pfam PF02811 PHP domain 44 215 4.6E-34 T 06-07-2017 IPR004013 PHP domain GO:0003824 CAK77_RS18435 205a7de499e89e20e1bd2ad6775c01a8 1078 SMART SM00481 43 110 5.6E-23 T 06-07-2017 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 CAK77_RS18435 205a7de499e89e20e1bd2ad6775c01a8 1078 SUPERFAMILY SSF89550 43 259 1.26E-20 T 06-07-2017 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CAK77_RS18435 205a7de499e89e20e1bd2ad6775c01a8 1078 Gene3D G3DSA:2.40.50.140 987 1065 4.4E-4 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS18435 205a7de499e89e20e1bd2ad6775c01a8 1078 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 334 748 1.5E-136 T 06-07-2017 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAK77_RS18435 205a7de499e89e20e1bd2ad6775c01a8 1078 Gene3D G3DSA:1.10.150.280 852 897 3.0E-6 T 06-07-2017 CAK77_RS18435 205a7de499e89e20e1bd2ad6775c01a8 1078 Gene3D G3DSA:3.20.20.140 43 261 1.2E-26 T 06-07-2017 CAK77_RS18435 205a7de499e89e20e1bd2ad6775c01a8 1078 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 43 914 3.3E-194 T 06-07-2017 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAK77_RS18435 205a7de499e89e20e1bd2ad6775c01a8 1078 Pfam PF14579 Helix-hairpin-helix motif 824 912 1.3E-23 T 06-07-2017 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAK77_RS18435 205a7de499e89e20e1bd2ad6775c01a8 1078 Pfam PF01336 OB-fold nucleic acid binding domain 991 1065 1.4E-6 T 06-07-2017 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CAK77_RS13325 288517405aa38288a19a8368e1c5afdf 275 ProDom PD040491 SCO1799 RV1486C/MT1533 MB1522C CGL1536 ML1804 MAV321 4 226 4.0E-60 T 06-07-2017 CAK77_RS03995 291c62a799eb0641f5a5803e40dd264a 268 SMART SM00862 149 223 8.1E-28 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAK77_RS03995 291c62a799eb0641f5a5803e40dd264a 268 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 222 1.0E-27 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAK77_RS03995 291c62a799eb0641f5a5803e40dd264a 268 Gene3D G3DSA:1.10.10.10 128 223 1.6E-33 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS03995 291c62a799eb0641f5a5803e40dd264a 268 SUPERFAMILY SSF46894 128 222 1.05E-28 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAK77_RS16155 c25138a6d40ac5c079b6561b97b4b161 92 ProSitePatterns PS00151 Acylphosphatase signature 2. 35 51 - T 06-07-2017 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CAK77_RS16155 c25138a6d40ac5c079b6561b97b4b161 92 Gene3D G3DSA:3.30.70.100 5 90 1.6E-26 T 06-07-2017 CAK77_RS16155 c25138a6d40ac5c079b6561b97b4b161 92 Pfam PF00708 Acylphosphatase 6 90 3.4E-21 T 06-07-2017 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CAK77_RS16155 c25138a6d40ac5c079b6561b97b4b161 92 SUPERFAMILY SSF54975 5 90 1.26E-23 T 06-07-2017 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CAK77_RS16155 c25138a6d40ac5c079b6561b97b4b161 92 ProSitePatterns PS00150 Acylphosphatase signature 1. 11 21 - T 06-07-2017 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CAK77_RS23490 8ea305f70504f20c835863c219e27265 230 SUPERFAMILY SSF51735 4 150 1.97E-31 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS23490 8ea305f70504f20c835863c219e27265 230 Pfam PF02080 TrkA-C domain 156 219 4.2E-10 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CAK77_RS23490 8ea305f70504f20c835863c219e27265 230 PRINTS PR00335 TrkA potassium uptake protein signature 77 91 2.2E-8 T 06-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 CAK77_RS23490 8ea305f70504f20c835863c219e27265 230 PRINTS PR00335 TrkA potassium uptake protein signature 24 38 2.2E-8 T 06-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 CAK77_RS23490 8ea305f70504f20c835863c219e27265 230 PRINTS PR00335 TrkA potassium uptake protein signature 7 21 2.2E-8 T 06-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 CAK77_RS23490 8ea305f70504f20c835863c219e27265 230 PRINTS PR00335 TrkA potassium uptake protein signature 64 74 2.2E-8 T 06-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 CAK77_RS23490 8ea305f70504f20c835863c219e27265 230 Pfam PF02254 TrkA-N domain 8 123 2.3E-26 T 06-07-2017 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 CAK77_RS23490 8ea305f70504f20c835863c219e27265 230 SUPERFAMILY SSF116726 139 216 2.22E-11 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CAK77_RS23490 8ea305f70504f20c835863c219e27265 230 Gene3D G3DSA:3.30.70.1450 153 213 8.0E-8 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CAK77_RS23490 8ea305f70504f20c835863c219e27265 230 Gene3D G3DSA:3.40.50.720 4 151 1.6E-33 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS22690 d248cb6df2f910c6885f33bc0815fd79 515 Gene3D G3DSA:3.30.300.30 407 507 3.0E-34 T 06-07-2017 CAK77_RS22690 d248cb6df2f910c6885f33bc0815fd79 515 ProSitePatterns PS00455 Putative AMP-binding domain signature. 163 174 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK77_RS22690 d248cb6df2f910c6885f33bc0815fd79 515 Gene3D G3DSA:3.40.50.980 173 323 2.7E-40 T 06-07-2017 CAK77_RS22690 d248cb6df2f910c6885f33bc0815fd79 515 Gene3D G3DSA:3.40.50.980 148 172 1.6E-29 T 06-07-2017 CAK77_RS22690 d248cb6df2f910c6885f33bc0815fd79 515 Gene3D G3DSA:3.40.50.980 3 114 1.6E-29 T 06-07-2017 CAK77_RS22690 d248cb6df2f910c6885f33bc0815fd79 515 Pfam PF00501 AMP-binding enzyme 9 412 1.7E-96 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK77_RS22690 d248cb6df2f910c6885f33bc0815fd79 515 Pfam PF13193 AMP-binding enzyme C-terminal domain 421 496 1.1E-22 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAK77_RS22690 d248cb6df2f910c6885f33bc0815fd79 515 Gene3D G3DSA:2.30.38.10 331 403 1.5E-27 T 06-07-2017 CAK77_RS22690 d248cb6df2f910c6885f33bc0815fd79 515 SUPERFAMILY SSF56801 4 508 3.79E-149 T 06-07-2017 CAK77_RS19490 8d5161c60a2b336fc0a33d156333301f 185 Gene3D G3DSA:3.40.50.880 3 181 2.8E-54 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAK77_RS19490 8d5161c60a2b336fc0a33d156333301f 185 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 10 178 5.2E-43 T 06-07-2017 IPR006286 Peptidase C56, PfpI CAK77_RS19490 8d5161c60a2b336fc0a33d156333301f 185 SUPERFAMILY SSF52317 10 178 4.03E-43 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAK77_RS19490 8d5161c60a2b336fc0a33d156333301f 185 Pfam PF01965 DJ-1/PfpI family 10 176 3.5E-46 T 06-07-2017 IPR002818 DJ-1/PfpI CAK77_RS09425 765549d8644bc916f77c0b95aee82e9e 249 Pfam PF13829 Domain of unknown function (DUF4191) 23 239 2.2E-83 T 06-07-2017 IPR025445 Protein of unknown function DUF4191 CAK77_RS09425 765549d8644bc916f77c0b95aee82e9e 249 ProDom PD037701 MEMBRANE INTEGRAL TRANSMEMBRANE RV2219/MT2276 NARROWLY PROBABLE PRECURSOR SIGNAL MLCB22.21 32 237 5.0E-68 T 06-07-2017 CAK77_RS21800 f74d897c9229ab85933149efed254a21 201 SUPERFAMILY SSF46689 4 80 4.26E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS21800 f74d897c9229ab85933149efed254a21 201 Gene3D G3DSA:1.10.357.10 57 198 2.3E-26 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS21800 f74d897c9229ab85933149efed254a21 201 SUPERFAMILY SSF48498 79 197 1.81E-31 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS21800 f74d897c9229ab85933149efed254a21 201 Gene3D G3DSA:1.10.10.60 4 56 3.8E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS21800 f74d897c9229ab85933149efed254a21 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 59 2.1E-12 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS21800 f74d897c9229ab85933149efed254a21 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 2.8E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS21800 f74d897c9229ab85933149efed254a21 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 2.8E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS08425 dbd7dd580331480816e06f07a7627187 332 Pfam PF13531 Bacterial extracellular solute-binding protein 34 279 5.9E-34 T 06-07-2017 CAK77_RS08425 dbd7dd580331480816e06f07a7627187 332 Gene3D G3DSA:3.40.190.10 33 133 1.8E-12 T 06-07-2017 CAK77_RS08425 dbd7dd580331480816e06f07a7627187 332 SUPERFAMILY SSF53850 30 327 1.3E-55 T 06-07-2017 CAK77_RS08425 dbd7dd580331480816e06f07a7627187 332 TIGRFAM TIGR00971 3a0106s03: sulfate ABC transporter, sulfate-binding protein 32 323 5.7E-49 T 06-07-2017 IPR005669 Thiosulphate/Sulfate-binding protein GO:0008272|GO:0015419 CAK77_RS08425 dbd7dd580331480816e06f07a7627187 332 Gene3D G3DSA:3.40.190.10 134 277 1.2E-46 T 06-07-2017 CAK77_RS12095 11a6e5be9c0b4bdde01d5e2d96646da0 110 PIRSF PIRSF010611 1 110 3.5E-34 T 06-07-2017 IPR016572 Uncharacterised conserved protein UCP010611 CAK77_RS12095 11a6e5be9c0b4bdde01d5e2d96646da0 110 TIGRFAM TIGR04529 MTB_hemophore: hemophore-related protein, Rv0203/Rv1174c family 39 110 7.8E-18 T 06-07-2017 IPR032407 Haemophore, haem-binding GO:0020037 CAK77_RS03605 bbd6e1c208a30272011a3b8b1f8ea22b 216 Gene3D G3DSA:3.60.15.10 1 187 2.6E-27 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK77_RS03605 bbd6e1c208a30272011a3b8b1f8ea22b 216 SUPERFAMILY SSF56281 1 184 7.99E-24 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK77_RS03605 bbd6e1c208a30272011a3b8b1f8ea22b 216 Pfam PF13483 Beta-lactamase superfamily domain 2 181 2.2E-19 T 06-07-2017 CAK77_RS03605 bbd6e1c208a30272011a3b8b1f8ea22b 216 SMART SM00849 7 181 5.9E-9 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK77_RS15630 cdc050dee9240fa6744813c6d6a3afa8 398 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 161 372 1.3E-47 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAK77_RS15630 cdc050dee9240fa6744813c6d6a3afa8 398 Gene3D G3DSA:3.30.950.10 275 394 3.5E-41 T 06-07-2017 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAK77_RS15630 cdc050dee9240fa6744813c6d6a3afa8 398 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 161 395 1.4E-79 T 06-07-2017 IPR006366 Uroporphyrin-III C-methyltransferase GO:0006779|GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CAK77_RS15630 cdc050dee9240fa6744813c6d6a3afa8 398 Gene3D G3DSA:3.40.50.720 8 108 3.9E-26 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS15630 cdc050dee9240fa6744813c6d6a3afa8 398 Gene3D G3DSA:3.40.1010.10 160 274 7.2E-39 T 06-07-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAK77_RS15630 cdc050dee9240fa6744813c6d6a3afa8 398 Pfam PF13241 Putative NAD(P)-binding 10 114 3.2E-21 T 06-07-2017 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CAK77_RS15630 cdc050dee9240fa6744813c6d6a3afa8 398 SUPERFAMILY SSF53790 155 394 9.03E-71 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAK77_RS15630 cdc050dee9240fa6744813c6d6a3afa8 398 SUPERFAMILY SSF51735 7 104 2.89E-15 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS13180 030a6b6b14491aac366a39de06b79c5b 441 Pfam PF00202 Aminotransferase class-III 29 429 3.4E-116 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAK77_RS13180 030a6b6b14491aac366a39de06b79c5b 441 SUPERFAMILY SSF53383 8 431 5.18E-116 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK77_RS13180 030a6b6b14491aac366a39de06b79c5b 441 Gene3D G3DSA:3.40.640.10 72 334 1.7E-86 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK77_RS13180 030a6b6b14491aac366a39de06b79c5b 441 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 249 286 - T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAK77_RS13180 030a6b6b14491aac366a39de06b79c5b 441 TIGRFAM TIGR00508 bioA: adenosylmethionine-8-amino-7-oxononanoate transaminase 17 430 4.3E-165 T 06-07-2017 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 CAK77_RS13180 030a6b6b14491aac366a39de06b79c5b 441 Hamap MF_00834 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [bioA]. 5 434 48.537 T 06-07-2017 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 CAK77_RS13180 030a6b6b14491aac366a39de06b79c5b 441 Gene3D G3DSA:3.90.1150.10 7 71 6.7E-45 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK77_RS13180 030a6b6b14491aac366a39de06b79c5b 441 Gene3D G3DSA:3.90.1150.10 339 432 6.7E-45 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK77_RS10505 38154fe1c2fb95c24ae2e13ba1f9f142 438 SMART SM00487 13 213 2.4E-47 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain CAK77_RS10505 38154fe1c2fb95c24ae2e13ba1f9f142 438 Pfam PF00271 Helicase conserved C-terminal domain 229 329 2.8E-21 T 06-07-2017 IPR001650 Helicase, C-terminal CAK77_RS10505 38154fe1c2fb95c24ae2e13ba1f9f142 438 SUPERFAMILY SSF52540 65 347 1.44E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS10505 38154fe1c2fb95c24ae2e13ba1f9f142 438 SMART SM00490 248 329 6.4E-26 T 06-07-2017 IPR001650 Helicase, C-terminal CAK77_RS10505 38154fe1c2fb95c24ae2e13ba1f9f142 438 Gene3D G3DSA:3.40.50.300 2 202 6.7E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS10505 38154fe1c2fb95c24ae2e13ba1f9f142 438 Pfam PF00270 DEAD/DEAH box helicase 18 187 2.1E-45 T 06-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CAK77_RS10505 38154fe1c2fb95c24ae2e13ba1f9f142 438 Gene3D G3DSA:3.40.50.300 203 356 6.0E-38 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS22930 d9263e80eb75514261194e6e526405f0 305 Gene3D G3DSA:3.40.50.150 19 206 1.4E-14 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS22930 d9263e80eb75514261194e6e526405f0 305 SUPERFAMILY SSF53335 14 296 1.16E-70 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS22930 d9263e80eb75514261194e6e526405f0 305 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 16 285 3.4E-82 T 06-07-2017 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 CAK77_RS22930 d9263e80eb75514261194e6e526405f0 305 Pfam PF04072 Leucine carboxyl methyltransferase 18 198 3.7E-59 T 06-07-2017 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 CAK77_RS19115 14df0fe5fb613780b780ae5aa91a84a9 464 Pfam PF00732 GMC oxidoreductase 1 282 2.4E-61 T 06-07-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CAK77_RS19115 14df0fe5fb613780b780ae5aa91a84a9 464 TIGRFAM TIGR03970 Rv0697: dehydrogenase, Rv0697 family 1 461 2.7E-164 T 06-07-2017 IPR023978 Glucose-methanol-choline oxidoreductase, actinobacteria CAK77_RS19115 14df0fe5fb613780b780ae5aa91a84a9 464 SUPERFAMILY SSF51905 1 275 1.69E-60 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS19115 14df0fe5fb613780b780ae5aa91a84a9 464 SUPERFAMILY SSF51905 404 462 1.69E-60 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS19115 14df0fe5fb613780b780ae5aa91a84a9 464 SUPERFAMILY SSF54373 326 389 7.98E-12 T 06-07-2017 CAK77_RS19115 14df0fe5fb613780b780ae5aa91a84a9 464 Gene3D G3DSA:3.50.50.60 176 300 2.0E-82 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS19115 14df0fe5fb613780b780ae5aa91a84a9 464 Gene3D G3DSA:3.50.50.60 398 461 2.0E-82 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS19115 14df0fe5fb613780b780ae5aa91a84a9 464 Gene3D G3DSA:3.50.50.60 1 99 2.0E-82 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS19115 14df0fe5fb613780b780ae5aa91a84a9 464 Gene3D G3DSA:3.30.560.10 100 175 1.8E-17 T 06-07-2017 CAK77_RS19115 14df0fe5fb613780b780ae5aa91a84a9 464 Pfam PF05199 GMC oxidoreductase 343 457 2.4E-25 T 06-07-2017 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 CAK77_RS13840 6ea0d5aefbf9bc1dbb1456aee75fc57b 444 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 14 429 1.5E-151 T 06-07-2017 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686 CAK77_RS13840 6ea0d5aefbf9bc1dbb1456aee75fc57b 444 Gene3D G3DSA:2.30.40.10 3 69 4.7E-16 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK77_RS13840 6ea0d5aefbf9bc1dbb1456aee75fc57b 444 SUPERFAMILY SSF51556 55 370 7.14E-98 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK77_RS13840 6ea0d5aefbf9bc1dbb1456aee75fc57b 444 ProSitePatterns PS00483 Dihydroorotase signature 2. 305 316 - T 06-07-2017 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686 CAK77_RS13840 6ea0d5aefbf9bc1dbb1456aee75fc57b 444 Hamap MF_00220_B Dihydroorotase [pyrC]. 2 429 42.859 T 06-07-2017 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686 CAK77_RS13840 6ea0d5aefbf9bc1dbb1456aee75fc57b 444 Pfam PF01979 Amidohydrolase family 51 424 4.4E-22 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAK77_RS13840 6ea0d5aefbf9bc1dbb1456aee75fc57b 444 Gene3D G3DSA:3.20.20.140 70 411 5.1E-104 T 06-07-2017 CAK77_RS13840 6ea0d5aefbf9bc1dbb1456aee75fc57b 444 SUPERFAMILY SSF51338 2 54 3.49E-22 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK77_RS13840 6ea0d5aefbf9bc1dbb1456aee75fc57b 444 SUPERFAMILY SSF51338 371 432 3.49E-22 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK77_RS06720 8536ca5c37a52004d0ab158488f0680f 250 SUPERFAMILY SSF102405 38 238 1.18E-61 T 06-07-2017 CAK77_RS06720 8536ca5c37a52004d0ab158488f0680f 250 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 65 238 5.7E-42 T 06-07-2017 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG CAK77_RS06720 8536ca5c37a52004d0ab158488f0680f 250 Gene3D G3DSA:3.40.50.450 44 240 4.2E-63 T 06-07-2017 CAK77_RS06720 8536ca5c37a52004d0ab158488f0680f 250 Pfam PF03641 Possible lysine decarboxylase 108 237 4.9E-33 T 06-07-2017 IPR031100 LOG family CAK77_RS14930 08ad7d2c8553c446c782af885ab11f6a 292 SUPERFAMILY SSF88946 11 84 3.1E-15 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS14930 08ad7d2c8553c446c782af885ab11f6a 292 Gene3D G3DSA:1.10.10.10 110 170 3.3E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS14930 08ad7d2c8553c446c782af885ab11f6a 292 SUPERFAMILY SSF88659 110 170 1.33E-11 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS14930 08ad7d2c8553c446c782af885ab11f6a 292 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 15 170 5.0E-19 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS14930 08ad7d2c8553c446c782af885ab11f6a 292 Pfam PF08281 Sigma-70, region 4 115 167 2.8E-11 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS14930 08ad7d2c8553c446c782af885ab11f6a 292 Pfam PF04542 Sigma-70 region 2 16 78 6.0E-14 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS14930 08ad7d2c8553c446c782af885ab11f6a 292 Gene3D G3DSA:1.10.1740.10 12 80 1.1E-14 T 06-07-2017 CAK77_RS24075 59b108528775c0c42fa5685caa89703a 874 SUPERFAMILY SSF52540 197 232 1.37E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS24075 59b108528775c0c42fa5685caa89703a 874 SUPERFAMILY SSF51294 365 379 1.71E-5 T 06-07-2017 IPR028992 Hedgehog/Intein (Hint) domain CAK77_RS24075 59b108528775c0c42fa5685caa89703a 874 SUPERFAMILY SSF51294 576 648 1.71E-5 T 06-07-2017 IPR028992 Hedgehog/Intein (Hint) domain CAK77_RS24075 59b108528775c0c42fa5685caa89703a 874 SUPERFAMILY SSF51294 234 338 1.71E-5 T 06-07-2017 IPR028992 Hedgehog/Intein (Hint) domain CAK77_RS24075 59b108528775c0c42fa5685caa89703a 874 Pfam PF00772 DnaB-like helicase N terminal domain 23 125 4.3E-34 T 06-07-2017 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 CAK77_RS24075 59b108528775c0c42fa5685caa89703a 874 PRINTS PR00379 Intein signature 544 559 1.3E-5 T 06-07-2017 IPR006142 Intein GO:0016539 CAK77_RS24075 59b108528775c0c42fa5685caa89703a 874 PRINTS PR00379 Intein signature 368 380 1.3E-5 T 06-07-2017 IPR006142 Intein GO:0016539 CAK77_RS24075 59b108528775c0c42fa5685caa89703a 874 PRINTS PR00379 Intein signature 517 529 1.3E-5 T 06-07-2017 IPR006142 Intein GO:0016539 CAK77_RS24075 59b108528775c0c42fa5685caa89703a 874 PRINTS PR00379 Intein signature 288 301 1.3E-5 T 06-07-2017 IPR006142 Intein GO:0016539 CAK77_RS24075 59b108528775c0c42fa5685caa89703a 874 Gene3D G3DSA:2.170.16.10 236 336 6.5E-9 T 06-07-2017 IPR028992 Hedgehog/Intein (Hint) domain CAK77_RS24075 59b108528775c0c42fa5685caa89703a 874 Gene3D G3DSA:2.170.16.10 598 649 6.5E-9 T 06-07-2017 IPR028992 Hedgehog/Intein (Hint) domain CAK77_RS24075 59b108528775c0c42fa5685caa89703a 874 SUPERFAMILY SSF48024 22 133 1.7E-36 T 06-07-2017 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 CAK77_RS24075 59b108528775c0c42fa5685caa89703a 874 SMART SM00306 231 370 5.0E-5 T 06-07-2017 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 CAK77_RS24075 59b108528775c0c42fa5685caa89703a 874 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 24 873 1.7E-158 T 06-07-2017 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 CAK77_RS24075 59b108528775c0c42fa5685caa89703a 874 SUPERFAMILY SSF52540 649 859 1.64E-35 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS24075 59b108528775c0c42fa5685caa89703a 874 Pfam PF03796 DnaB-like helicase C terminal domain 201 233 7.1E-10 T 06-07-2017 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 CAK77_RS24075 59b108528775c0c42fa5685caa89703a 874 Pfam PF03796 DnaB-like helicase C terminal domain 648 871 1.7E-84 T 06-07-2017 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 CAK77_RS24075 59b108528775c0c42fa5685caa89703a 874 SUPERFAMILY SSF55608 499 593 2.66E-15 T 06-07-2017 IPR027434 Homing endonuclease GO:0004519 CAK77_RS24075 59b108528775c0c42fa5685caa89703a 874 Gene3D G3DSA:3.40.50.300 185 235 2.9E-115 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS24075 59b108528775c0c42fa5685caa89703a 874 Gene3D G3DSA:3.40.50.300 656 873 2.9E-115 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS24075 59b108528775c0c42fa5685caa89703a 874 Gene3D G3DSA:3.10.28.10 504 593 7.6E-20 T 06-07-2017 IPR027434 Homing endonuclease GO:0004519 CAK77_RS24075 59b108528775c0c42fa5685caa89703a 874 Gene3D G3DSA:1.10.860.10 24 126 5.6E-39 T 06-07-2017 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal CAK77_RS22645 e4e64b29c8edb778a725815f37f9ea66 250 Pfam PF10979 Protein of unknown function (DUF2786) 7 43 1.1E-11 T 06-07-2017 IPR024498 Domain of unknown function DUF2786 CAK77_RS22645 e4e64b29c8edb778a725815f37f9ea66 250 ProDom PD120223 SCO3432 GENE ML2604 GP79 GP77 CGL2230 MB0190 1 247 1.0E-93 T 06-07-2017 CAK77_RS12985 efddb0e03ba713bf5432c370ed2671ea 472 SUPERFAMILY SSF52935 321 468 9.03E-36 T 06-07-2017 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CAK77_RS12985 efddb0e03ba713bf5432c370ed2671ea 472 Gene3D G3DSA:3.40.1380.20 324 465 6.7E-38 T 06-07-2017 IPR015794 Pyruvate kinase, alpha/beta GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CAK77_RS12985 efddb0e03ba713bf5432c370ed2671ea 472 Gene3D G3DSA:2.40.33.10 74 167 4.0E-28 T 06-07-2017 IPR015806 Pyruvate kinase, beta-barrel insert domain GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CAK77_RS12985 efddb0e03ba713bf5432c370ed2671ea 472 Gene3D G3DSA:3.20.20.60 168 323 4.9E-100 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAK77_RS12985 efddb0e03ba713bf5432c370ed2671ea 472 Gene3D G3DSA:3.20.20.60 3 73 4.9E-100 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAK77_RS12985 efddb0e03ba713bf5432c370ed2671ea 472 SUPERFAMILY SSF51621 166 337 6.98E-96 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAK77_RS12985 efddb0e03ba713bf5432c370ed2671ea 472 SUPERFAMILY SSF51621 2 76 6.98E-96 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAK77_RS12985 efddb0e03ba713bf5432c370ed2671ea 472 Pfam PF02887 Pyruvate kinase, alpha/beta domain 354 465 8.3E-23 T 06-07-2017 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CAK77_RS12985 efddb0e03ba713bf5432c370ed2671ea 472 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 3 467 3.6E-168 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CAK77_RS12985 efddb0e03ba713bf5432c370ed2671ea 472 Pfam PF00224 Pyruvate kinase, barrel domain 3 335 1.6E-119 T 06-07-2017 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CAK77_RS12985 efddb0e03ba713bf5432c370ed2671ea 472 ProSitePatterns PS00110 Pyruvate kinase active site signature. 213 225 - T 06-07-2017 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CAK77_RS12985 efddb0e03ba713bf5432c370ed2671ea 472 SUPERFAMILY SSF50800 71 165 3.31E-24 T 06-07-2017 IPR011037 Pyruvate kinase-like, insert domain CAK77_RS12985 efddb0e03ba713bf5432c370ed2671ea 472 PRINTS PR01050 Pyruvate kinase family signature 311 327 9.7E-66 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CAK77_RS12985 efddb0e03ba713bf5432c370ed2671ea 472 PRINTS PR01050 Pyruvate kinase family signature 215 241 9.7E-66 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CAK77_RS12985 efddb0e03ba713bf5432c370ed2671ea 472 PRINTS PR01050 Pyruvate kinase family signature 242 266 9.7E-66 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CAK77_RS12985 efddb0e03ba713bf5432c370ed2671ea 472 PRINTS PR01050 Pyruvate kinase family signature 267 291 9.7E-66 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CAK77_RS12985 efddb0e03ba713bf5432c370ed2671ea 472 PRINTS PR01050 Pyruvate kinase family signature 185 199 9.7E-66 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CAK77_RS12985 efddb0e03ba713bf5432c370ed2671ea 472 PRINTS PR01050 Pyruvate kinase family signature 60 76 9.7E-66 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CAK77_RS12985 efddb0e03ba713bf5432c370ed2671ea 472 PRINTS PR01050 Pyruvate kinase family signature 292 310 9.7E-66 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CAK77_RS20330 777c9cdc72fe93baf9755fc82bec065e 153 Gene3D G3DSA:3.30.530.20 10 128 7.3E-8 T 06-07-2017 IPR023393 START-like domain CAK77_RS20330 777c9cdc72fe93baf9755fc82bec065e 153 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 5 129 2.6E-8 T 06-07-2017 IPR019587 Polyketide cyclase/dehydrase CAK77_RS20330 777c9cdc72fe93baf9755fc82bec065e 153 SUPERFAMILY SSF55961 9 142 9.58E-19 T 06-07-2017 CAK77_RS03930 6f831145645e6d82a7923f3a65b3f1f2 205 Pfam PF08768 Domain of unknown function (DUF1794) 45 202 1.1E-41 T 06-07-2017 IPR014878 Domain of unknown function DUF1794 CAK77_RS03930 6f831145645e6d82a7923f3a65b3f1f2 205 SUPERFAMILY SSF50814 38 202 3.56E-33 T 06-07-2017 IPR011038 Calycin-like CAK77_RS03930 6f831145645e6d82a7923f3a65b3f1f2 205 Hamap MF_01297 UPF0678 fatty acid-binding protein-like protein . 36 204 29.89 T 06-07-2017 IPR022939 Uncharacterised protein family UPF0678 CAK77_RS06745 bf045848408888c13bdc84eb72218465 302 SUPERFAMILY SSF51717 22 293 1.7E-76 T 06-07-2017 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAK77_RS06745 bf045848408888c13bdc84eb72218465 302 Pfam PF00809 Pterin binding enzyme 29 273 5.5E-67 T 06-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAK77_RS06745 bf045848408888c13bdc84eb72218465 302 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 28 286 3.0E-83 T 06-07-2017 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 CAK77_RS06745 bf045848408888c13bdc84eb72218465 302 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 28 43 - T 06-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAK77_RS06745 bf045848408888c13bdc84eb72218465 302 Gene3D G3DSA:3.20.20.20 23 290 8.1E-82 T 06-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAK77_RS06745 bf045848408888c13bdc84eb72218465 302 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 62 75 - T 06-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAK77_RS17915 b04c7bb645491ffc07447abf1fe2296e 405 ProSitePatterns PS00965 Phosphomannose isomerase type I signature 1. 126 134 - T 06-07-2017 IPR018050 Phosphomannose isomerase, type I, conserved site GO:0004476 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 CAK77_RS17915 b04c7bb645491ffc07447abf1fe2296e 405 Pfam PF01238 Phosphomannose isomerase type I 4 363 8.7E-63 T 06-07-2017 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 CAK77_RS17915 b04c7bb645491ffc07447abf1fe2296e 405 SUPERFAMILY SSF51182 4 393 1.36E-94 T 06-07-2017 IPR011051 RmlC-like cupin domain CAK77_RS17915 b04c7bb645491ffc07447abf1fe2296e 405 PRINTS PR00714 Phosphomannose isomerase type I signature 32 47 1.9E-63 T 06-07-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 CAK77_RS17915 b04c7bb645491ffc07447abf1fe2296e 405 PRINTS PR00714 Phosphomannose isomerase type I signature 245 264 1.9E-63 T 06-07-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 CAK77_RS17915 b04c7bb645491ffc07447abf1fe2296e 405 PRINTS PR00714 Phosphomannose isomerase type I signature 81 102 1.9E-63 T 06-07-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 CAK77_RS17915 b04c7bb645491ffc07447abf1fe2296e 405 PRINTS PR00714 Phosphomannose isomerase type I signature 229 244 1.9E-63 T 06-07-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 CAK77_RS17915 b04c7bb645491ffc07447abf1fe2296e 405 PRINTS PR00714 Phosphomannose isomerase type I signature 264 283 1.9E-63 T 06-07-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 CAK77_RS17915 b04c7bb645491ffc07447abf1fe2296e 405 PRINTS PR00714 Phosphomannose isomerase type I signature 4 22 1.9E-63 T 06-07-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 CAK77_RS17915 b04c7bb645491ffc07447abf1fe2296e 405 PRINTS PR00714 Phosphomannose isomerase type I signature 126 149 1.9E-63 T 06-07-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 CAK77_RS17915 b04c7bb645491ffc07447abf1fe2296e 405 PRINTS PR00714 Phosphomannose isomerase type I signature 283 302 1.9E-63 T 06-07-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 CAK77_RS17915 b04c7bb645491ffc07447abf1fe2296e 405 PIRSF PIRSF001480 1 405 2.0E-101 T 06-07-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 CAK77_RS17915 b04c7bb645491ffc07447abf1fe2296e 405 TIGRFAM TIGR00218 manA: mannose-6-phosphate isomerase, class I 6 394 3.0E-72 T 06-07-2017 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 CAK77_RS17915 b04c7bb645491ffc07447abf1fe2296e 405 Gene3D G3DSA:1.10.441.10 141 240 7.3E-19 T 06-07-2017 CAK77_RS17915 b04c7bb645491ffc07447abf1fe2296e 405 Gene3D G3DSA:1.10.441.10 283 295 7.3E-19 T 06-07-2017 CAK77_RS17915 b04c7bb645491ffc07447abf1fe2296e 405 Gene3D G3DSA:2.60.120.10 247 282 3.3E-57 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK77_RS17915 b04c7bb645491ffc07447abf1fe2296e 405 Gene3D G3DSA:2.60.120.10 7 140 3.3E-57 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK77_RS17915 b04c7bb645491ffc07447abf1fe2296e 405 Gene3D G3DSA:2.60.120.10 296 402 3.9E-19 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK77_RS11355 b6eee3c70011123a8eea2c06260643ef 493 SUPERFAMILY SSF46689 137 185 2.82E-7 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS11355 b6eee3c70011123a8eea2c06260643ef 493 Gene3D G3DSA:1.10.10.60 137 185 1.7E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS11355 b6eee3c70011123a8eea2c06260643ef 493 Pfam PF06029 AlkA N-terminal domain 203 317 1.8E-24 T 06-07-2017 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal CAK77_RS11355 b6eee3c70011123a8eea2c06260643ef 493 Pfam PF12833 Helix-turn-helix domain 106 184 9.0E-17 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK77_RS11355 b6eee3c70011123a8eea2c06260643ef 493 SUPERFAMILY SSF57884 3 83 2.48E-32 T 06-07-2017 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 CAK77_RS11355 b6eee3c70011123a8eea2c06260643ef 493 SMART SM01009 202 317 3.8E-27 T 06-07-2017 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal CAK77_RS11355 b6eee3c70011123a8eea2c06260643ef 493 Gene3D G3DSA:3.40.10.10 2 83 1.7E-34 T 06-07-2017 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 CAK77_RS11355 b6eee3c70011123a8eea2c06260643ef 493 SUPERFAMILY SSF48150 307 476 1.4E-33 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CAK77_RS11355 b6eee3c70011123a8eea2c06260643ef 493 Gene3D G3DSA:1.10.340.30 320 433 1.1E-28 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CAK77_RS11355 b6eee3c70011123a8eea2c06260643ef 493 SMART SM00478 327 477 3.2E-8 T 06-07-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CAK77_RS11355 b6eee3c70011123a8eea2c06260643ef 493 SMART SM00342 100 183 5.2E-16 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK77_RS11355 b6eee3c70011123a8eea2c06260643ef 493 Gene3D G3DSA:3.30.310.20 203 317 4.4E-26 T 06-07-2017 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal CAK77_RS11355 b6eee3c70011123a8eea2c06260643ef 493 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 137 179 - T 06-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CAK77_RS11355 b6eee3c70011123a8eea2c06260643ef 493 Gene3D G3DSA:1.10.1670.10 435 475 3.8E-7 T 06-07-2017 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CAK77_RS11355 b6eee3c70011123a8eea2c06260643ef 493 Pfam PF02805 Metal binding domain of Ada 7 71 7.3E-30 T 06-07-2017 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 CAK77_RS11355 b6eee3c70011123a8eea2c06260643ef 493 SUPERFAMILY SSF55945 203 296 2.51E-15 T 06-07-2017 CAK77_RS03235 ca870923474ae3acc028bd2448d4e4e4 302 Gene3D G3DSA:3.30.360.10 140 272 3.1E-67 T 06-07-2017 CAK77_RS03235 ca870923474ae3acc028bd2448d4e4e4 302 SUPERFAMILY SSF51735 4 151 7.03E-24 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS03235 ca870923474ae3acc028bd2448d4e4e4 302 SUPERFAMILY SSF55347 127 272 2.81E-59 T 06-07-2017 CAK77_RS03235 ca870923474ae3acc028bd2448d4e4e4 302 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 7 114 2.3E-9 T 06-07-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CAK77_RS03235 ca870923474ae3acc028bd2448d4e4e4 302 SMART SM00859 6 119 2.3E-5 T 06-07-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CAK77_RS03235 ca870923474ae3acc028bd2448d4e4e4 302 Pfam PF09290 Prokaryotic acetaldehyde dehydrogenase, dimerisation 127 272 7.6E-64 T 06-07-2017 IPR015426 Acetaldehyde dehydrogenase, C-terminal GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 CAK77_RS03235 ca870923474ae3acc028bd2448d4e4e4 302 Hamap MF_01657 Acetaldehyde dehydrogenase [mhpF]. 1 302 141.081 T 06-07-2017 IPR003361 Acetaldehyde dehydrogenase GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 CAK77_RS03235 ca870923474ae3acc028bd2448d4e4e4 302 TIGRFAM TIGR03215 ac_ald_DH_ac: acetaldehyde dehydrogenase (acetylating) 4 297 2.6E-136 T 06-07-2017 IPR003361 Acetaldehyde dehydrogenase GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 CAK77_RS03235 ca870923474ae3acc028bd2448d4e4e4 302 Gene3D G3DSA:3.40.50.720 3 139 2.4E-69 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS03235 ca870923474ae3acc028bd2448d4e4e4 302 PIRSF PIRSF015689 1 302 4.1E-137 T 06-07-2017 IPR003361 Acetaldehyde dehydrogenase GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 CAK77_RS08970 5abf7bcfb4c2e83fe052442379742221 584 Gene3D G3DSA:3.40.50.980 6 175 3.5E-36 T 06-07-2017 CAK77_RS08970 5abf7bcfb4c2e83fe052442379742221 584 Pfam PF00501 AMP-binding enzyme 11 454 3.9E-91 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK77_RS08970 5abf7bcfb4c2e83fe052442379742221 584 Gene3D G3DSA:2.30.38.10 390 449 2.9E-19 T 06-07-2017 CAK77_RS08970 5abf7bcfb4c2e83fe052442379742221 584 Gene3D G3DSA:3.40.50.980 322 383 1.1E-26 T 06-07-2017 CAK77_RS08970 5abf7bcfb4c2e83fe052442379742221 584 Gene3D G3DSA:3.40.50.980 176 268 1.1E-26 T 06-07-2017 CAK77_RS08970 5abf7bcfb4c2e83fe052442379742221 584 ProSitePatterns PS00455 Putative AMP-binding domain signature. 170 181 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK77_RS08970 5abf7bcfb4c2e83fe052442379742221 584 SUPERFAMILY SSF56801 5 273 2.62E-117 T 06-07-2017 CAK77_RS08970 5abf7bcfb4c2e83fe052442379742221 584 SUPERFAMILY SSF56801 325 584 2.62E-117 T 06-07-2017 CAK77_RS01290 b043485acbd8d1c5e281b6b99f215594 529 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 254 268 - T 06-07-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CAK77_RS01290 b043485acbd8d1c5e281b6b99f215594 529 Gene3D G3DSA:3.50.50.60 6 127 3.3E-116 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS01290 b043485acbd8d1c5e281b6b99f215594 529 Gene3D G3DSA:3.50.50.60 187 313 3.3E-116 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS01290 b043485acbd8d1c5e281b6b99f215594 529 Gene3D G3DSA:3.50.50.60 463 526 3.3E-116 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS01290 b043485acbd8d1c5e281b6b99f215594 529 SUPERFAMILY SSF54373 290 470 2.65E-39 T 06-07-2017 CAK77_RS01290 b043485acbd8d1c5e281b6b99f215594 529 Pfam PF05199 GMC oxidoreductase 381 520 1.3E-35 T 06-07-2017 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 CAK77_RS01290 b043485acbd8d1c5e281b6b99f215594 529 SUPERFAMILY SSF51905 469 526 1.73E-74 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS01290 b043485acbd8d1c5e281b6b99f215594 529 SUPERFAMILY SSF51905 6 288 1.73E-74 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS01290 b043485acbd8d1c5e281b6b99f215594 529 ProSitePatterns PS00623 GMC oxidoreductases signature 1. 83 106 - T 06-07-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CAK77_RS01290 b043485acbd8d1c5e281b6b99f215594 529 PIRSF PIRSF000137 3 528 2.3E-143 T 06-07-2017 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 KEGG: 00260+1.2.1.8+1.1.99.1|MetaCyc: PWY-3722|MetaCyc: PWY-7494|Reactome: R-HSA-6798163 CAK77_RS01290 b043485acbd8d1c5e281b6b99f215594 529 Pfam PF00732 GMC oxidoreductase 8 296 1.3E-89 T 06-07-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CAK77_RS20905 2aab17b3c354a811ffa78191b9e58697 448 PIRSF PIRSF000362 1 447 2.4E-153 T 06-07-2017 IPR021163 Ferredoxin-NADP+ reductase, adrenodoxin-type GO:0016491|GO:0055114 Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 CAK77_RS20905 2aab17b3c354a811ffa78191b9e58697 448 PRINTS PR00419 Adrenodoxin reductase family signature 144 158 4.7E-22 T 06-07-2017 CAK77_RS20905 2aab17b3c354a811ffa78191b9e58697 448 PRINTS PR00419 Adrenodoxin reductase family signature 5 27 4.7E-22 T 06-07-2017 CAK77_RS20905 2aab17b3c354a811ffa78191b9e58697 448 PRINTS PR00419 Adrenodoxin reductase family signature 73 83 4.7E-22 T 06-07-2017 CAK77_RS20905 2aab17b3c354a811ffa78191b9e58697 448 PRINTS PR00419 Adrenodoxin reductase family signature 30 43 4.7E-22 T 06-07-2017 CAK77_RS20905 2aab17b3c354a811ffa78191b9e58697 448 Gene3D G3DSA:3.50.50.60 95 314 1.5E-62 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS20905 2aab17b3c354a811ffa78191b9e58697 448 SUPERFAMILY SSF51971 259 315 1.65E-56 T 06-07-2017 CAK77_RS20905 2aab17b3c354a811ffa78191b9e58697 448 SUPERFAMILY SSF51971 3 210 1.65E-56 T 06-07-2017 CAK77_RS20905 2aab17b3c354a811ffa78191b9e58697 448 SUPERFAMILY SSF51971 302 443 2.77E-9 T 06-07-2017 CAK77_RS20905 2aab17b3c354a811ffa78191b9e58697 448 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 165 7.7E-9 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS20905 2aab17b3c354a811ffa78191b9e58697 448 Gene3D G3DSA:3.40.50.720 315 442 5.7E-75 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS20905 2aab17b3c354a811ffa78191b9e58697 448 Gene3D G3DSA:3.40.50.720 4 94 5.7E-75 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS21860 eefe30c3b49f3e108ca3fce0ae03d5fa 546 Pfam PF00501 AMP-binding enzyme 22 436 9.3E-111 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK77_RS21860 eefe30c3b49f3e108ca3fce0ae03d5fa 546 ProSitePatterns PS00455 Putative AMP-binding domain signature. 185 196 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK77_RS21860 eefe30c3b49f3e108ca3fce0ae03d5fa 546 Gene3D G3DSA:3.40.50.980 16 199 3.7E-44 T 06-07-2017 CAK77_RS21860 eefe30c3b49f3e108ca3fce0ae03d5fa 546 SUPERFAMILY SSF56801 12 532 9.42E-161 T 06-07-2017 CAK77_RS21860 eefe30c3b49f3e108ca3fce0ae03d5fa 546 Gene3D G3DSA:3.40.50.980 200 345 9.0E-48 T 06-07-2017 CAK77_RS21860 eefe30c3b49f3e108ca3fce0ae03d5fa 546 Gene3D G3DSA:3.30.300.30 433 533 4.8E-32 T 06-07-2017 CAK77_RS21860 eefe30c3b49f3e108ca3fce0ae03d5fa 546 Pfam PF13193 AMP-binding enzyme C-terminal domain 445 521 4.6E-16 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAK77_RS21860 eefe30c3b49f3e108ca3fce0ae03d5fa 546 Gene3D G3DSA:2.30.38.10 353 426 3.8E-29 T 06-07-2017 CAK77_RS13790 0f89680e073e97a88bea9cdb525bacf1 400 PIRSF PIRSF000497 1 400 3.2E-165 T 06-07-2017 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CAK77_RS13790 0f89680e073e97a88bea9cdb525bacf1 400 Gene3D G3DSA:3.30.300.10 261 399 3.2E-69 T 06-07-2017 CAK77_RS13790 0f89680e073e97a88bea9cdb525bacf1 400 SUPERFAMILY SSF55973 250 398 5.1E-68 T 06-07-2017 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CAK77_RS13790 0f89680e073e97a88bea9cdb525bacf1 400 Gene3D G3DSA:3.30.300.10 13 147 5.9E-48 T 06-07-2017 CAK77_RS13790 0f89680e073e97a88bea9cdb525bacf1 400 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 250 389 3.9E-67 T 06-07-2017 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CAK77_RS13790 0f89680e073e97a88bea9cdb525bacf1 400 Pfam PF02772 S-adenosylmethionine synthetase, central domain 127 248 1.8E-43 T 06-07-2017 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CAK77_RS13790 0f89680e073e97a88bea9cdb525bacf1 400 Gene3D G3DSA:3.30.300.10 148 250 5.6E-38 T 06-07-2017 CAK77_RS13790 0f89680e073e97a88bea9cdb525bacf1 400 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 4 400 57.183 T 06-07-2017 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CAK77_RS13790 0f89680e073e97a88bea9cdb525bacf1 400 SUPERFAMILY SSF55973 123 249 2.2E-44 T 06-07-2017 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CAK77_RS13790 0f89680e073e97a88bea9cdb525bacf1 400 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 128 138 - T 06-07-2017 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CAK77_RS13790 0f89680e073e97a88bea9cdb525bacf1 400 SUPERFAMILY SSF55973 6 111 4.32E-46 T 06-07-2017 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CAK77_RS13790 0f89680e073e97a88bea9cdb525bacf1 400 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 7 399 6.5E-169 T 06-07-2017 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CAK77_RS13790 0f89680e073e97a88bea9cdb525bacf1 400 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 7 103 6.1E-42 T 06-07-2017 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CAK77_RS13790 0f89680e073e97a88bea9cdb525bacf1 400 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 276 284 - T 06-07-2017 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CAK77_RS07545 b9f39f5e8264084da330eb74ee177c72 375 Gene3D G3DSA:3.50.50.60 1 78 2.9E-32 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS07545 b9f39f5e8264084da330eb74ee177c72 375 Gene3D G3DSA:3.50.50.60 333 373 2.9E-32 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS07545 b9f39f5e8264084da330eb74ee177c72 375 Gene3D G3DSA:3.50.50.60 131 213 2.9E-32 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS07545 b9f39f5e8264084da330eb74ee177c72 375 Pfam PF01266 FAD dependent oxidoreductase 3 372 7.5E-42 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CAK77_RS07545 b9f39f5e8264084da330eb74ee177c72 375 SUPERFAMILY SSF51905 1 215 1.68E-36 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS07545 b9f39f5e8264084da330eb74ee177c72 375 SUPERFAMILY SSF51905 333 373 1.68E-36 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS07545 b9f39f5e8264084da330eb74ee177c72 375 TIGRFAM TIGR03364 HpnW_proposed: FAD dependent oxidoreductase TIGR03364 2 367 3.4E-104 T 06-07-2017 IPR017741 FAD-dependent oxidoreductase, HpnW CAK77_RS14855 a9f453a3f436e8dfcc772af378d9b68f 389 SUPERFAMILY SSF51726 51 388 1.29E-96 T 06-07-2017 CAK77_RS14855 a9f453a3f436e8dfcc772af378d9b68f 389 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 182 198 - T 06-07-2017 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CAK77_RS14855 a9f453a3f436e8dfcc772af378d9b68f 389 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 49 389 43.863 T 06-07-2017 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CAK77_RS14855 a9f453a3f436e8dfcc772af378d9b68f 389 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 52 388 9.7E-119 T 06-07-2017 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CAK77_RS14855 a9f453a3f436e8dfcc772af378d9b68f 389 Gene3D G3DSA:3.20.20.210 41 388 9.4E-138 T 06-07-2017 CAK77_RS14855 a9f453a3f436e8dfcc772af378d9b68f 389 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 65 74 - T 06-07-2017 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CAK77_RS14855 a9f453a3f436e8dfcc772af378d9b68f 389 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 51 388 8.5E-121 T 06-07-2017 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CAK77_RS15740 cdb3470ed61b5166436a15c4f44e888c 503 Gene3D G3DSA:3.40.50.880 259 439 6.2E-31 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAK77_RS15740 cdb3470ed61b5166436a15c4f44e888c 503 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 9 232 6.0E-25 T 06-07-2017 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain CAK77_RS15740 cdb3470ed61b5166436a15c4f44e888c 503 SUPERFAMILY SSF52317 260 436 5.0E-35 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAK77_RS15740 cdb3470ed61b5166436a15c4f44e888c 503 SUPERFAMILY SSF52540 1 242 1.46E-51 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS15740 cdb3470ed61b5166436a15c4f44e888c 503 TIGRFAM TIGR00313 cobQ: cobyric acid synthase CobQ 5 478 1.0E-140 T 06-07-2017 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 CAK77_RS15740 cdb3470ed61b5166436a15c4f44e888c 503 Hamap MF_00028 Cobyric acid synthase [cobQ]. 1 486 174.841 T 06-07-2017 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 CAK77_RS15740 cdb3470ed61b5166436a15c4f44e888c 503 Gene3D G3DSA:3.40.50.300 4 239 9.1E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS15740 cdb3470ed61b5166436a15c4f44e888c 503 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 259 430 1.1E-41 T 06-07-2017 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 CAK77_RS01120 0c34ec31f7218c0f91d979974d404821 259 Gene3D G3DSA:3.40.50.720 9 255 4.9E-36 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS01120 0c34ec31f7218c0f91d979974d404821 259 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 146 174 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK77_RS01120 0c34ec31f7218c0f91d979974d404821 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 3.8E-15 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS01120 0c34ec31f7218c0f91d979974d404821 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 3.8E-15 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS01120 0c34ec31f7218c0f91d979974d404821 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 3.8E-15 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS01120 0c34ec31f7218c0f91d979974d404821 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 3.8E-15 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS01120 0c34ec31f7218c0f91d979974d404821 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 3.8E-15 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS01120 0c34ec31f7218c0f91d979974d404821 259 Pfam PF00106 short chain dehydrogenase 10 199 3.8E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS01120 0c34ec31f7218c0f91d979974d404821 259 SUPERFAMILY SSF51735 8 256 2.65E-39 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS13860 f4a5394e40b3dabbbdff57565ec6a0b5 227 Gene3D G3DSA:3.40.50.150 26 201 2.6E-34 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS13860 f4a5394e40b3dabbbdff57565ec6a0b5 227 Pfam PF13847 Methyltransferase domain 48 150 1.1E-13 T 06-07-2017 IPR025714 Methyltransferase domain CAK77_RS13860 f4a5394e40b3dabbbdff57565ec6a0b5 227 SUPERFAMILY SSF53335 24 188 4.59E-32 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS20585 70abe0c30b5c1fe2bf032fd68b9a971f 422 Gene3D G3DSA:3.40.50.2000 1 260 4.2E-58 T 06-07-2017 CAK77_RS20585 70abe0c30b5c1fe2bf032fd68b9a971f 422 SUPERFAMILY SSF53756 1 417 8.64E-89 T 06-07-2017 CAK77_RS20585 70abe0c30b5c1fe2bf032fd68b9a971f 422 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 3 86 6.6E-9 T 06-07-2017 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CAK77_RS20585 70abe0c30b5c1fe2bf032fd68b9a971f 422 Gene3D G3DSA:3.40.50.2000 261 391 6.4E-8 T 06-07-2017 CAK77_RS13945 f20a8d7a236579729e04583b0e056fdf 891 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 891 168.599 T 06-07-2017 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 CAK77_RS13945 f20a8d7a236579729e04583b0e056fdf 891 SUPERFAMILY SSF101353 249 443 4.32E-55 T 06-07-2017 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 CAK77_RS13945 f20a8d7a236579729e04583b0e056fdf 891 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 5 871 2.0E-250 T 06-07-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CAK77_RS13945 f20a8d7a236579729e04583b0e056fdf 891 Gene3D G3DSA:3.30.930.10 1 244 7.1E-94 T 06-07-2017 CAK77_RS13945 f20a8d7a236579729e04583b0e056fdf 891 SUPERFAMILY SSF55186 564 721 2.75E-42 T 06-07-2017 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 CAK77_RS13945 f20a8d7a236579729e04583b0e056fdf 891 Pfam PF01411 tRNA synthetases class II (A) 5 567 8.6E-204 T 06-07-2017 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 CAK77_RS13945 f20a8d7a236579729e04583b0e056fdf 891 SUPERFAMILY SSF55681 2 248 1.94E-88 T 06-07-2017 CAK77_RS13945 f20a8d7a236579729e04583b0e056fdf 891 SMART SM00863 665 709 2.4E-18 T 06-07-2017 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CAK77_RS13945 f20a8d7a236579729e04583b0e056fdf 891 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 665 709 1.6E-14 T 06-07-2017 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CAK77_RS13945 f20a8d7a236579729e04583b0e056fdf 891 SUPERFAMILY SSF50447 461 564 1.66E-15 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain CAK77_RS13945 f20a8d7a236579729e04583b0e056fdf 891 Pfam PF02272 DHHA1 domain 816 885 1.1E-8 T 06-07-2017 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 CAK77_RS13945 f20a8d7a236579729e04583b0e056fdf 891 PRINTS PR00980 Alanyl-tRNA synthetase signature 229 242 3.0E-26 T 06-07-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CAK77_RS13945 f20a8d7a236579729e04583b0e056fdf 891 PRINTS PR00980 Alanyl-tRNA synthetase signature 280 296 3.0E-26 T 06-07-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CAK77_RS13945 f20a8d7a236579729e04583b0e056fdf 891 PRINTS PR00980 Alanyl-tRNA synthetase signature 196 207 3.0E-26 T 06-07-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CAK77_RS13945 f20a8d7a236579729e04583b0e056fdf 891 PRINTS PR00980 Alanyl-tRNA synthetase signature 69 80 3.0E-26 T 06-07-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CAK77_RS13945 f20a8d7a236579729e04583b0e056fdf 891 PRINTS PR00980 Alanyl-tRNA synthetase signature 304 317 3.0E-26 T 06-07-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CAK77_RS19900 beffb23957430751f29be80f1b2518e1 503 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 251 410 1.2E-10 T 06-07-2017 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain CAK77_RS19900 beffb23957430751f29be80f1b2518e1 503 SUPERFAMILY SSF52540 249 484 3.36E-28 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS19900 beffb23957430751f29be80f1b2518e1 503 Gene3D G3DSA:3.40.50.300 249 485 2.1E-30 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS05820 7172ca16f9381c256c8fb652f4d1a90c 619 Gene3D G3DSA:2.30.38.10 402 491 5.6E-19 T 06-07-2017 CAK77_RS05820 7172ca16f9381c256c8fb652f4d1a90c 619 Gene3D G3DSA:3.30.300.30 495 610 1.3E-13 T 06-07-2017 CAK77_RS05820 7172ca16f9381c256c8fb652f4d1a90c 619 Gene3D G3DSA:3.40.50.980 34 204 5.8E-26 T 06-07-2017 CAK77_RS05820 7172ca16f9381c256c8fb652f4d1a90c 619 SUPERFAMILY SSF56801 31 615 1.3E-98 T 06-07-2017 CAK77_RS05820 7172ca16f9381c256c8fb652f4d1a90c 619 Gene3D G3DSA:3.40.50.980 205 369 4.2E-25 T 06-07-2017 CAK77_RS05820 7172ca16f9381c256c8fb652f4d1a90c 619 Pfam PF00501 AMP-binding enzyme 42 503 1.1E-71 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK77_RS08465 2e6f2aca830244381be9ce1a8d81258b 237 Gene3D G3DSA:3.40.50.620 15 208 2.0E-53 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS08465 2e6f2aca830244381be9ce1a8d81258b 237 TIGRFAM TIGR00434 cysH: phosophoadenylyl-sulfate reductase 29 235 3.0E-55 T 06-07-2017 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 CAK77_RS08465 2e6f2aca830244381be9ce1a8d81258b 237 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 46 211 4.6E-41 T 06-07-2017 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 CAK77_RS08465 2e6f2aca830244381be9ce1a8d81258b 237 SUPERFAMILY SSF52402 23 200 3.77E-41 T 06-07-2017 CAK77_RS08465 2e6f2aca830244381be9ce1a8d81258b 237 Hamap MF_00063 Phosphoadenosine phosphosulfate reductase [cysH]. 5 236 35.465 T 06-07-2017 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 CAK77_RS08465 2e6f2aca830244381be9ce1a8d81258b 237 TIGRFAM TIGR02055 APS_reductase: adenylylsulfate reductase, thioredoxin dependent 48 234 3.6E-72 T 06-07-2017 IPR011798 Adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019344|GO:0055114 KEGG: 00920+1.8.4.8 CAK77_RS08465 2e6f2aca830244381be9ce1a8d81258b 237 PIRSF PIRSF000857 1 237 3.2E-85 T 06-07-2017 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 CAK77_RS11535 b9956f28fa2897aeac2477c1fa9cf910 253 SUPERFAMILY SSF46785 41 120 1.07E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS11535 b9956f28fa2897aeac2477c1fa9cf910 253 Gene3D G3DSA:1.10.10.10 41 120 2.8E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS11535 b9956f28fa2897aeac2477c1fa9cf910 253 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 46 207 4.7E-31 T 06-07-2017 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 CAK77_RS11535 b9956f28fa2897aeac2477c1fa9cf910 253 SUPERFAMILY SSF46785 125 197 3.26E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS11535 b9956f28fa2897aeac2477c1fa9cf910 253 Gene3D G3DSA:1.10.10.10 125 197 4.7E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS11535 b9956f28fa2897aeac2477c1fa9cf910 253 Pfam PF04079 Segregation and condensation complex subunit ScpB 49 205 8.7E-50 T 06-07-2017 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 CAK77_RS10080 eb25b9075c14a1805619b44d525ca76e 509 Gene3D G3DSA:3.50.50.60 15 220 5.0E-58 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS10080 eb25b9075c14a1805619b44d525ca76e 509 Gene3D G3DSA:3.50.50.60 327 490 7.6E-18 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS10080 eb25b9075c14a1805619b44d525ca76e 509 SUPERFAMILY SSF51905 14 253 9.2E-55 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS10080 eb25b9075c14a1805619b44d525ca76e 509 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 17 218 3.5E-19 T 06-07-2017 CAK77_RS10080 eb25b9075c14a1805619b44d525ca76e 509 SUPERFAMILY SSF51905 281 475 2.81E-22 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS02365 a8bc0114e44c0844d70e969237a56aba 304 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 120 304 4.9E-32 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS02365 a8bc0114e44c0844d70e969237a56aba 304 Gene3D G3DSA:1.10.3720.10 96 301 1.1E-28 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS02365 a8bc0114e44c0844d70e969237a56aba 304 SUPERFAMILY SSF161098 99 286 2.49E-25 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS21755 09ae7851f0ef573c1cbbeb8e9128386b 522 Pfam PF13520 Amino acid permease 20 466 2.0E-27 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CAK77_RS21755 09ae7851f0ef573c1cbbeb8e9128386b 522 PIRSF PIRSF006060 3 495 3.6E-51 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CAK77_RS03535 ec73a0d80b38c37482cd56258df5d446 422 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 4 416 39.722 T 06-07-2017 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CAK77_RS03535 ec73a0d80b38c37482cd56258df5d446 422 Gene3D G3DSA:3.40.50.20 5 96 4.7E-32 T 06-07-2017 IPR016185 Pre-ATP-grasp domain CAK77_RS03535 ec73a0d80b38c37482cd56258df5d446 422 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 4 416 3.6E-150 T 06-07-2017 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CAK77_RS03535 ec73a0d80b38c37482cd56258df5d446 422 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 328 413 1.2E-25 T 06-07-2017 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CAK77_RS03535 ec73a0d80b38c37482cd56258df5d446 422 SUPERFAMILY SSF56059 105 316 3.16E-50 T 06-07-2017 CAK77_RS03535 ec73a0d80b38c37482cd56258df5d446 422 Gene3D G3DSA:3.30.470.20 188 324 8.4E-55 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAK77_RS03535 ec73a0d80b38c37482cd56258df5d446 422 SMART SM01209 104 292 2.6E-107 T 06-07-2017 CAK77_RS03535 ec73a0d80b38c37482cd56258df5d446 422 SUPERFAMILY SSF51246 326 415 5.34E-23 T 06-07-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAK77_RS03535 ec73a0d80b38c37482cd56258df5d446 422 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 104 292 4.4E-68 T 06-07-2017 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CAK77_RS03535 ec73a0d80b38c37482cd56258df5d446 422 Gene3D G3DSA:3.90.600.10 328 415 1.4E-28 T 06-07-2017 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CAK77_RS03535 ec73a0d80b38c37482cd56258df5d446 422 SMART SM01210 327 416 1.2E-37 T 06-07-2017 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CAK77_RS03535 ec73a0d80b38c37482cd56258df5d446 422 SUPERFAMILY SSF52440 4 104 1.87E-31 T 06-07-2017 IPR016185 Pre-ATP-grasp domain CAK77_RS03535 ec73a0d80b38c37482cd56258df5d446 422 Gene3D G3DSA:3.30.1490.20 125 187 1.1E-13 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CAK77_RS03535 ec73a0d80b38c37482cd56258df5d446 422 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 5 103 4.4E-30 T 06-07-2017 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CAK77_RS03535 ec73a0d80b38c37482cd56258df5d446 422 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 286 293 - T 06-07-2017 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CAK77_RS22410 5ad9d5c05714c9146c8ec8560f3f3c42 265 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 45 265 28.539 T 06-07-2017 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 CAK77_RS22410 5ad9d5c05714c9146c8ec8560f3f3c42 265 Gene3D G3DSA:3.40.50.150 93 221 5.8E-16 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS22410 5ad9d5c05714c9146c8ec8560f3f3c42 265 Pfam PF02390 Putative methyltransferase 91 257 1.3E-52 T 06-07-2017 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 CAK77_RS22410 5ad9d5c05714c9146c8ec8560f3f3c42 265 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 85 264 4.9E-40 T 06-07-2017 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 CAK77_RS22410 5ad9d5c05714c9146c8ec8560f3f3c42 265 SUPERFAMILY SSF53335 89 262 3.32E-32 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS12485 615dd5d6eb490a1a04c13b0e0f14c8ff 803 Gene3D G3DSA:3.40.50.970 51 373 1.7E-18 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK77_RS12485 615dd5d6eb490a1a04c13b0e0f14c8ff 803 Pfam PF09363 XFP C-terminal domain 595 798 7.3E-85 T 06-07-2017 IPR018969 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, C-terminal GO:0005975|GO:0016832 CAK77_RS12485 615dd5d6eb490a1a04c13b0e0f14c8ff 803 SUPERFAMILY SSF52518 386 601 6.47E-22 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK77_RS12485 615dd5d6eb490a1a04c13b0e0f14c8ff 803 ProSitePatterns PS60002 Phosphoketolase signature 1. 152 158 - T 06-07-2017 IPR019790 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, conserved site GO:0005975|GO:0016832 CAK77_RS12485 615dd5d6eb490a1a04c13b0e0f14c8ff 803 Pfam PF03894 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase 408 584 2.6E-87 T 06-07-2017 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 CAK77_RS12485 615dd5d6eb490a1a04c13b0e0f14c8ff 803 PIRSF PIRSF017245 1 800 0.0 T 06-07-2017 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 CAK77_RS12485 615dd5d6eb490a1a04c13b0e0f14c8ff 803 Pfam PF09364 XFP N-terminal domain 16 393 2.8E-175 T 06-07-2017 IPR018970 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, N-terminal CAK77_RS12485 615dd5d6eb490a1a04c13b0e0f14c8ff 803 SUPERFAMILY SSF52518 5 377 4.42E-67 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK77_RS12485 615dd5d6eb490a1a04c13b0e0f14c8ff 803 ProSitePatterns PS60003 Phosphoketolase signature 2. 165 183 - T 06-07-2017 IPR019789 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, thiamine diphosphate binding site GO:0005975|GO:0016832 CAK77_RS12485 615dd5d6eb490a1a04c13b0e0f14c8ff 803 Hamap MF_01403 Probable phosphoketolase. 13 800 38.823 T 06-07-2017 IPR023962 Probable phosphoketolase CAK77_RS19370 43549db86a18d4be434ae45f55911519 324 Pfam PF00561 alpha/beta hydrolase fold 34 291 6.0E-22 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS19370 43549db86a18d4be434ae45f55911519 324 Gene3D G3DSA:3.40.50.1820 13 303 5.8E-68 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS19370 43549db86a18d4be434ae45f55911519 324 SUPERFAMILY SSF53474 11 299 2.22E-61 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS09690 7930ff05bac5df91ef35762d31d93d53 326 Pfam PF02219 Methylenetetrahydrofolate reductase 29 316 5.2E-82 T 06-07-2017 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 CAK77_RS09690 7930ff05bac5df91ef35762d31d93d53 326 Gene3D G3DSA:3.20.20.220 27 318 1.1E-89 T 06-07-2017 IPR029041 FAD-linked oxidoreductase-like CAK77_RS09690 7930ff05bac5df91ef35762d31d93d53 326 TIGRFAM TIGR00676 fadh2: methylenetetrahydrofolate reductase [NAD(P)H] 35 315 4.9E-90 T 06-07-2017 IPR004620 5,10-methylenetetrahydrofolate reductase GO:0004489|GO:0005829|GO:0009086|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841 CAK77_RS09690 7930ff05bac5df91ef35762d31d93d53 326 SUPERFAMILY SSF51730 27 318 2.16E-81 T 06-07-2017 IPR029041 FAD-linked oxidoreductase-like CAK77_RS02790 a39a4a00f8f1fb6e4b8ee8bbcab7c413 126 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 3 116 6.8E-36 T 06-07-2017 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CAK77_RS02790 a39a4a00f8f1fb6e4b8ee8bbcab7c413 126 TIGRFAM TIGR00526 folB_dom: FolB domain 3 121 4.0E-31 T 06-07-2017 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CAK77_RS02790 a39a4a00f8f1fb6e4b8ee8bbcab7c413 126 SMART SM00905 5 117 2.0E-48 T 06-07-2017 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CAK77_RS02790 a39a4a00f8f1fb6e4b8ee8bbcab7c413 126 Gene3D G3DSA:3.30.1130.10 1 119 1.9E-42 T 06-07-2017 CAK77_RS02790 a39a4a00f8f1fb6e4b8ee8bbcab7c413 126 Pfam PF02152 Dihydroneopterin aldolase 5 114 1.0E-31 T 06-07-2017 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CAK77_RS02790 a39a4a00f8f1fb6e4b8ee8bbcab7c413 126 SUPERFAMILY SSF55620 3 119 3.45E-34 T 06-07-2017 CAK77_RS12835 5134fbbb9fd89b87f874f1bec16b7528 441 SUPERFAMILY SSF53383 88 440 1.48E-81 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK77_RS12835 5134fbbb9fd89b87f874f1bec16b7528 441 Gene3D G3DSA:3.90.1150.10 317 440 4.2E-28 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK77_RS12835 5134fbbb9fd89b87f874f1bec16b7528 441 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 91 436 9.1E-99 T 06-07-2017 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CAK77_RS12835 5134fbbb9fd89b87f874f1bec16b7528 441 Gene3D G3DSA:3.40.640.10 88 313 2.2E-61 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK77_RS15780 342aeb3eff3363970f02a7e4edb218bf 389 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 7 380 3.6E-115 T 06-07-2017 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CAK77_RS15780 342aeb3eff3363970f02a7e4edb218bf 389 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 8 381 44.147 T 06-07-2017 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CAK77_RS15780 342aeb3eff3363970f02a7e4edb218bf 389 Gene3D G3DSA:3.40.50.720 7 144 6.1E-52 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS15780 342aeb3eff3363970f02a7e4edb218bf 389 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 8 128 1.0E-38 T 06-07-2017 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CAK77_RS15780 342aeb3eff3363970f02a7e4edb218bf 389 SUPERFAMILY SSF55347 122 258 7.52E-52 T 06-07-2017 CAK77_RS15780 342aeb3eff3363970f02a7e4edb218bf 389 SUPERFAMILY SSF51735 7 144 3.82E-36 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS15780 342aeb3eff3363970f02a7e4edb218bf 389 SUPERFAMILY SSF69055 287 382 2.35E-25 T 06-07-2017 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CAK77_RS15780 342aeb3eff3363970f02a7e4edb218bf 389 PIRSF PIRSF006205 5 388 9.7E-140 T 06-07-2017 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CAK77_RS15780 342aeb3eff3363970f02a7e4edb218bf 389 Gene3D G3DSA:1.10.1740.10 297 382 8.6E-28 T 06-07-2017 CAK77_RS15780 342aeb3eff3363970f02a7e4edb218bf 389 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 140 223 1.9E-33 T 06-07-2017 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CAK77_RS15780 342aeb3eff3363970f02a7e4edb218bf 389 Pfam PF13288 DXP reductoisomerase C-terminal domain 256 374 5.1E-34 T 06-07-2017 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CAK77_RS16300 c07ab68efb418238d9be1897bbb3cbc5 70 Gene3D G3DSA:3.30.70.20 8 67 1.3E-9 T 06-07-2017 CAK77_RS16300 c07ab68efb418238d9be1897bbb3cbc5 70 Pfam PF13459 4Fe-4S single cluster domain 8 65 6.6E-8 T 06-07-2017 CAK77_RS16300 c07ab68efb418238d9be1897bbb3cbc5 70 SUPERFAMILY SSF54862 7 65 1.79E-8 T 06-07-2017 CAK77_RS00855 1fc579cbd276d7325944d0110923b415 515 SUPERFAMILY SSF51905 11 229 3.7E-51 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS00855 1fc579cbd276d7325944d0110923b415 515 SUPERFAMILY SSF51905 305 403 3.7E-51 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS00855 1fc579cbd276d7325944d0110923b415 515 Gene3D G3DSA:3.50.50.60 309 349 7.7E-9 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS00855 1fc579cbd276d7325944d0110923b415 515 Gene3D G3DSA:3.50.50.60 236 237 7.7E-9 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS00855 1fc579cbd276d7325944d0110923b415 515 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 10 32 1.2E-6 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAK77_RS00855 1fc579cbd276d7325944d0110923b415 515 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 132 140 1.2E-6 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAK77_RS00855 1fc579cbd276d7325944d0110923b415 515 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 171 195 1.2E-6 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAK77_RS00855 1fc579cbd276d7325944d0110923b415 515 Gene3D G3DSA:3.50.50.60 10 211 1.1E-59 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS00855 1fc579cbd276d7325944d0110923b415 515 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 1.8E-5 T 06-07-2017 CAK77_RS00855 1fc579cbd276d7325944d0110923b415 515 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 175 193 1.8E-5 T 06-07-2017 CAK77_RS00855 1fc579cbd276d7325944d0110923b415 515 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 12 214 1.0E-16 T 06-07-2017 CAK77_RS12705 d56f0e648ccb68f0157720612a73c03b 470 Gene3D G3DSA:1.10.287.130 235 290 4.0E-17 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK77_RS12705 d56f0e648ccb68f0157720612a73c03b 470 Pfam PF00672 HAMP domain 149 226 1.2E-12 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAK77_RS12705 d56f0e648ccb68f0157720612a73c03b 470 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 348 457 4.5E-20 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS12705 d56f0e648ccb68f0157720612a73c03b 470 SUPERFAMILY SSF55874 294 457 2.49E-40 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS12705 d56f0e648ccb68f0157720612a73c03b 470 Pfam PF00512 His Kinase A (phospho-acceptor) domain 240 305 2.8E-18 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK77_RS12705 d56f0e648ccb68f0157720612a73c03b 470 SMART SM00388 238 305 2.2E-20 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK77_RS12705 d56f0e648ccb68f0157720612a73c03b 470 PRINTS PR00344 Bacterial sensor protein C-terminal signature 403 413 3.8E-11 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK77_RS12705 d56f0e648ccb68f0157720612a73c03b 470 PRINTS PR00344 Bacterial sensor protein C-terminal signature 420 438 3.8E-11 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK77_RS12705 d56f0e648ccb68f0157720612a73c03b 470 PRINTS PR00344 Bacterial sensor protein C-terminal signature 443 456 3.8E-11 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK77_RS12705 d56f0e648ccb68f0157720612a73c03b 470 PRINTS PR00344 Bacterial sensor protein C-terminal signature 385 399 3.8E-11 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK77_RS12705 d56f0e648ccb68f0157720612a73c03b 470 SUPERFAMILY SSF47384 218 306 4.45E-19 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK77_RS12705 d56f0e648ccb68f0157720612a73c03b 470 SMART SM00387 348 459 4.7E-37 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS12705 d56f0e648ccb68f0157720612a73c03b 470 Gene3D G3DSA:3.30.565.10 291 461 2.9E-41 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS12705 d56f0e648ccb68f0157720612a73c03b 470 SMART SM00304 167 230 1.6E-6 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAK77_RS16045 e87965309bf3fd4acb9b6d776153809d 301 SUPERFAMILY SSF56601 69 283 2.32E-21 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK77_RS16045 e87965309bf3fd4acb9b6d776153809d 301 Gene3D G3DSA:3.40.710.10 68 290 2.1E-13 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK77_RS21410 2ca0657a445ddf51b39d07e1054841e2 190 Pfam PF00156 Phosphoribosyl transferase domain 81 166 6.1E-10 T 06-07-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 CAK77_RS21410 2ca0657a445ddf51b39d07e1054841e2 190 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 26 184 2.9E-33 T 06-07-2017 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CAK77_RS21410 2ca0657a445ddf51b39d07e1054841e2 190 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 190 25.223 T 06-07-2017 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CAK77_RS21410 2ca0657a445ddf51b39d07e1054841e2 190 Gene3D G3DSA:3.40.50.2020 14 185 2.2E-51 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like CAK77_RS21410 2ca0657a445ddf51b39d07e1054841e2 190 SUPERFAMILY SSF53271 15 185 6.56E-34 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like CAK77_RS17885 845149d3c2ad7986469d5a4b477a8f9a 235 Pfam PF00440 Bacterial regulatory proteins, tetR family 53 96 2.1E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS17885 845149d3c2ad7986469d5a4b477a8f9a 235 SUPERFAMILY SSF46689 45 113 1.6E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS17885 845149d3c2ad7986469d5a4b477a8f9a 235 Gene3D G3DSA:1.10.357.10 49 222 6.3E-20 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS17925 8b8fde4ef27842560d2b966cd5f4bc6d 469 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 183 202 4.6E-22 T 06-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK77_RS17925 8b8fde4ef27842560d2b966cd5f4bc6d 469 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 218 231 4.6E-22 T 06-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK77_RS17925 8b8fde4ef27842560d2b966cd5f4bc6d 469 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 247 262 4.6E-22 T 06-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK77_RS17925 8b8fde4ef27842560d2b966cd5f4bc6d 469 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 106 120 4.6E-22 T 06-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK77_RS17925 8b8fde4ef27842560d2b966cd5f4bc6d 469 SUPERFAMILY SSF53738 273 377 3.92E-31 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK77_RS17925 8b8fde4ef27842560d2b966cd5f4bc6d 469 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 167 267 3.4E-22 T 06-07-2017 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK77_RS17925 8b8fde4ef27842560d2b966cd5f4bc6d 469 Gene3D G3DSA:3.40.120.10 13 135 1.3E-28 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK77_RS17925 8b8fde4ef27842560d2b966cd5f4bc6d 469 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 386 462 3.4E-12 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK77_RS17925 8b8fde4ef27842560d2b966cd5f4bc6d 469 SUPERFAMILY SSF55957 381 464 1.83E-19 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK77_RS17925 8b8fde4ef27842560d2b966cd5f4bc6d 469 SUPERFAMILY SSF53738 11 135 3.61E-30 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK77_RS17925 8b8fde4ef27842560d2b966cd5f4bc6d 469 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 274 381 1.1E-25 T 06-07-2017 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK77_RS17925 8b8fde4ef27842560d2b966cd5f4bc6d 469 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 13 136 1.1E-28 T 06-07-2017 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK77_RS17925 8b8fde4ef27842560d2b966cd5f4bc6d 469 SUPERFAMILY SSF53738 167 269 4.71E-26 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK77_RS17925 8b8fde4ef27842560d2b966cd5f4bc6d 469 Gene3D G3DSA:3.40.120.10 185 263 3.5E-29 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK77_RS17925 8b8fde4ef27842560d2b966cd5f4bc6d 469 Gene3D G3DSA:3.30.310.50 384 464 1.8E-20 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK77_RS17925 8b8fde4ef27842560d2b966cd5f4bc6d 469 Gene3D G3DSA:3.40.120.10 264 381 7.8E-38 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK77_RS10945 509779b16a12f7bf046b8e469246bc91 453 Gene3D G3DSA:3.60.120.10 58 446 2.0E-80 T 06-07-2017 IPR005801 ADC synthase GO:0009058 CAK77_RS10945 509779b16a12f7bf046b8e469246bc91 453 TIGRFAM TIGR03494 salicyl_syn: salicylate synthase 35 449 2.8E-171 T 06-07-2017 IPR019996 Salicylate synthase GO:0008909|GO:0016833 KEGG: 00130+5.4.4.2|KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6120|MetaCyc: PWY-6406|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CAK77_RS10945 509779b16a12f7bf046b8e469246bc91 453 Pfam PF00425 chorismate binding enzyme 187 440 2.0E-62 T 06-07-2017 IPR015890 Chorismate-utilising enzyme, C-terminal CAK77_RS10945 509779b16a12f7bf046b8e469246bc91 453 PRINTS PR00095 Anthranilate synthase component I signature 397 411 4.3E-6 T 06-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CAK77_RS10945 509779b16a12f7bf046b8e469246bc91 453 PRINTS PR00095 Anthranilate synthase component I signature 288 301 4.3E-6 T 06-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CAK77_RS10945 509779b16a12f7bf046b8e469246bc91 453 PRINTS PR00095 Anthranilate synthase component I signature 382 396 4.3E-6 T 06-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CAK77_RS10945 509779b16a12f7bf046b8e469246bc91 453 SUPERFAMILY SSF56322 33 446 2.49E-91 T 06-07-2017 IPR005801 ADC synthase GO:0009058 CAK77_RS08260 7a4c926e20f277ad06b382e6d25fcf79 301 SMART SM00382 52 215 7.8E-6 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS08260 7a4c926e20f277ad06b382e6d25fcf79 301 SUPERFAMILY SSF52540 50 288 1.24E-33 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS08260 7a4c926e20f277ad06b382e6d25fcf79 301 Gene3D G3DSA:3.40.50.300 49 236 5.6E-30 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS08260 7a4c926e20f277ad06b382e6d25fcf79 301 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 56 204 5.0E-10 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 CAK77_RS05985 91d01aa39c8e38a4342f55b3ab6193d4 405 PIRSF PIRSF000429 1 405 1.2E-128 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 CAK77_RS05985 91d01aa39c8e38a4342f55b3ab6193d4 405 SUPERFAMILY SSF53901 282 403 3.11E-42 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS05985 91d01aa39c8e38a4342f55b3ab6193d4 405 Gene3D G3DSA:3.40.47.10 169 208 9.1E-59 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS05985 91d01aa39c8e38a4342f55b3ab6193d4 405 Gene3D G3DSA:3.40.47.10 288 403 9.1E-59 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS05985 91d01aa39c8e38a4342f55b3ab6193d4 405 ProSitePatterns PS00737 Thiolases signature 2. 350 366 - T 06-07-2017 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CAK77_RS05985 91d01aa39c8e38a4342f55b3ab6193d4 405 SUPERFAMILY SSF53901 3 281 2.02E-65 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS05985 91d01aa39c8e38a4342f55b3ab6193d4 405 Gene3D G3DSA:3.40.47.10 4 125 7.7E-58 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS05985 91d01aa39c8e38a4342f55b3ab6193d4 405 Gene3D G3DSA:3.40.47.10 209 287 7.7E-58 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS05985 91d01aa39c8e38a4342f55b3ab6193d4 405 Pfam PF00108 Thiolase, N-terminal domain 5 272 2.8E-61 T 06-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CAK77_RS05985 91d01aa39c8e38a4342f55b3ab6193d4 405 Pfam PF02803 Thiolase, C-terminal domain 281 403 7.5E-47 T 06-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CAK77_RS05985 91d01aa39c8e38a4342f55b3ab6193d4 405 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 402 7.3E-136 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 CAK77_RS03810 7c6199bb3f4aa3bb9d44df5598341c98 427 Gene3D G3DSA:3.40.50.1820 6 139 3.9E-36 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS03810 7c6199bb3f4aa3bb9d44df5598341c98 427 Gene3D G3DSA:3.40.50.1820 181 254 3.9E-36 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS03810 7c6199bb3f4aa3bb9d44df5598341c98 427 Pfam PF12146 Serine aminopeptidase, S33 47 132 9.7E-12 T 06-07-2017 IPR022742 Serine aminopeptidase, S33 CAK77_RS03810 7c6199bb3f4aa3bb9d44df5598341c98 427 SUPERFAMILY SSF82784 227 406 9.42E-40 T 06-07-2017 IPR003718 OsmC/Ohr family CAK77_RS03810 7c6199bb3f4aa3bb9d44df5598341c98 427 Gene3D G3DSA:3.30.300.20 278 407 3.6E-40 T 06-07-2017 IPR015946 K homology domain-like, alpha/beta CAK77_RS03810 7c6199bb3f4aa3bb9d44df5598341c98 427 SUPERFAMILY SSF53474 181 251 3.44E-42 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS03810 7c6199bb3f4aa3bb9d44df5598341c98 427 SUPERFAMILY SSF53474 4 138 3.44E-42 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS03810 7c6199bb3f4aa3bb9d44df5598341c98 427 Pfam PF02566 OsmC-like protein 303 405 1.1E-18 T 06-07-2017 IPR003718 OsmC/Ohr family CAK77_RS21435 3b00ebd3043fa628da9fc37646fec008 848 Gene3D G3DSA:1.10.8.60 768 844 1.5E-30 T 06-07-2017 CAK77_RS21435 3b00ebd3043fa628da9fc37646fec008 848 Gene3D G3DSA:1.10.8.60 344 427 5.4E-36 T 06-07-2017 CAK77_RS21435 3b00ebd3043fa628da9fc37646fec008 848 SUPERFAMILY SSF81923 7 155 3.34E-35 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 CAK77_RS21435 3b00ebd3043fa628da9fc37646fec008 848 Gene3D G3DSA:1.10.1780.10 6 146 3.0E-38 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 CAK77_RS21435 3b00ebd3043fa628da9fc37646fec008 848 SUPERFAMILY SSF52540 157 547 4.87E-96 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS21435 3b00ebd3043fa628da9fc37646fec008 848 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 677 695 8.2E-42 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 CAK77_RS21435 3b00ebd3043fa628da9fc37646fec008 848 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 710 724 8.2E-42 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 CAK77_RS21435 3b00ebd3043fa628da9fc37646fec008 848 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 648 666 8.2E-42 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 CAK77_RS21435 3b00ebd3043fa628da9fc37646fec008 848 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 603 621 8.2E-42 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 CAK77_RS21435 3b00ebd3043fa628da9fc37646fec008 848 Pfam PF07724 AAA domain (Cdc48 subfamily) 598 749 7.6E-49 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 CAK77_RS21435 3b00ebd3043fa628da9fc37646fec008 848 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 94 145 4.5E-11 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 CAK77_RS21435 3b00ebd3043fa628da9fc37646fec008 848 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 67 3.0E-9 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 CAK77_RS21435 3b00ebd3043fa628da9fc37646fec008 848 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 203 317 2.1E-12 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 CAK77_RS21435 3b00ebd3043fa628da9fc37646fec008 848 Gene3D G3DSA:3.40.50.300 159 342 1.4E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS21435 3b00ebd3043fa628da9fc37646fec008 848 SMART SM01086 756 847 1.3E-37 T 06-07-2017 IPR019489 Clp ATPase, C-terminal CAK77_RS21435 3b00ebd3043fa628da9fc37646fec008 848 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 756 835 7.8E-27 T 06-07-2017 IPR019489 Clp ATPase, C-terminal CAK77_RS21435 3b00ebd3043fa628da9fc37646fec008 848 SUPERFAMILY SSF52540 548 838 2.23E-78 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS21435 3b00ebd3043fa628da9fc37646fec008 848 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 633 651 - T 06-07-2017 IPR028299 ClpA/B, conserved site 2 CAK77_RS21435 3b00ebd3043fa628da9fc37646fec008 848 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 295 307 - T 06-07-2017 IPR018368 ClpA/B, conserved site 1 GO:0005524 CAK77_RS21435 3b00ebd3043fa628da9fc37646fec008 848 SMART SM00382 599 757 2.0E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS21435 3b00ebd3043fa628da9fc37646fec008 848 SMART SM00382 198 344 4.8E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS21435 3b00ebd3043fa628da9fc37646fec008 848 Gene3D G3DSA:3.40.50.300 555 767 1.9E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS21435 3b00ebd3043fa628da9fc37646fec008 848 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 7 841 0.0 T 06-07-2017 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0016485 CAK77_RS07390 992948f3a6539cf92730b62198840422 872 Pfam PF11897 Protein of unknown function (DUF3417) 13 130 5.1E-36 T 06-07-2017 IPR024517 Glycogen phosphorylase, domain of unknown function DUF3417 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 CAK77_RS07390 992948f3a6539cf92730b62198840422 872 Gene3D G3DSA:3.40.50.2000 25 433 8.9E-94 T 06-07-2017 CAK77_RS07390 992948f3a6539cf92730b62198840422 872 Pfam PF00343 Carbohydrate phosphorylase 256 633 7.9E-16 T 06-07-2017 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 CAK77_RS07390 992948f3a6539cf92730b62198840422 872 Pfam PF00343 Carbohydrate phosphorylase 135 180 2.2E-5 T 06-07-2017 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 CAK77_RS07390 992948f3a6539cf92730b62198840422 872 Gene3D G3DSA:3.40.50.2000 434 724 4.7E-85 T 06-07-2017 CAK77_RS07390 992948f3a6539cf92730b62198840422 872 TIGRFAM TIGR02094 more_P_ylases: alpha-glucan phosphorylases 117 721 3.3E-234 T 06-07-2017 IPR011834 Alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 CAK77_RS07390 992948f3a6539cf92730b62198840422 872 PIRSF PIRSF000460 1 810 5.8E-260 T 06-07-2017 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 CAK77_RS07390 992948f3a6539cf92730b62198840422 872 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 611 623 - T 06-07-2017 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 CAK77_RS07390 992948f3a6539cf92730b62198840422 872 SUPERFAMILY SSF53756 4 755 4.19E-196 T 06-07-2017 CAK77_RS22795 4baf60f61958ead9b0c5febfd73937be 341 SUPERFAMILY SSF47616 157 330 4.18E-34 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAK77_RS22795 4baf60f61958ead9b0c5febfd73937be 341 Pfam PF13410 Glutathione S-transferase, C-terminal domain 189 260 7.6E-14 T 06-07-2017 CAK77_RS22795 4baf60f61958ead9b0c5febfd73937be 341 SUPERFAMILY SSF52833 26 98 1.12E-5 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK77_RS22795 4baf60f61958ead9b0c5febfd73937be 341 Gene3D G3DSA:3.40.30.10 24 165 1.5E-14 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK77_RS22795 4baf60f61958ead9b0c5febfd73937be 341 Gene3D G3DSA:1.20.1050.10 166 277 2.4E-25 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAK77_RS22795 4baf60f61958ead9b0c5febfd73937be 341 PIRSF PIRSF015753 2 309 6.0E-109 T 06-07-2017 IPR016639 Glutathione S-transferase (GST) KEGG: 00480+2.5.1.18|KEGG: 00980+2.5.1.18|KEGG: 00982+2.5.1.18|MetaCyc: PWY-4061|MetaCyc: PWY-6842|MetaCyc: PWY-7112|MetaCyc: PWY-7533 CAK77_RS22795 4baf60f61958ead9b0c5febfd73937be 341 Pfam PF13409 Glutathione S-transferase, N-terminal domain 49 138 1.2E-9 T 06-07-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CAK77_RS23115 cfe51d23432fb2e4d7d5d0db4efeb015 221 SUPERFAMILY SSF46785 3 77 3.35E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS23115 cfe51d23432fb2e4d7d5d0db4efeb015 221 SUPERFAMILY SSF48008 90 219 2.62E-23 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAK77_RS23115 cfe51d23432fb2e4d7d5d0db4efeb015 221 Gene3D G3DSA:1.20.120.530 88 220 6.9E-26 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAK77_RS23115 cfe51d23432fb2e4d7d5d0db4efeb015 221 Gene3D G3DSA:1.10.10.10 6 76 1.5E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS23115 cfe51d23432fb2e4d7d5d0db4efeb015 221 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 33 47 1.1E-9 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK77_RS23115 cfe51d23432fb2e4d7d5d0db4efeb015 221 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 63 1.1E-9 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK77_RS23115 cfe51d23432fb2e4d7d5d0db4efeb015 221 SMART SM00345 14 73 3.0E-20 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK77_RS23115 cfe51d23432fb2e4d7d5d0db4efeb015 221 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 73 1.7E-20 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK77_RS23115 cfe51d23432fb2e4d7d5d0db4efeb015 221 SMART SM00895 93 217 1.3E-17 T 06-07-2017 IPR011711 GntR, C-terminal CAK77_RS23115 cfe51d23432fb2e4d7d5d0db4efeb015 221 Pfam PF07729 FCD domain 95 215 5.0E-22 T 06-07-2017 IPR011711 GntR, C-terminal CAK77_RS17035 e71971bcb7425d721552d0e8488cf57e 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 52 75 1.2E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS17035 e71971bcb7425d721552d0e8488cf57e 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 31 44 1.2E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS17035 e71971bcb7425d721552d0e8488cf57e 204 SUPERFAMILY SSF46689 21 83 1.24E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS17035 e71971bcb7425d721552d0e8488cf57e 204 Gene3D G3DSA:1.10.357.10 18 202 5.9E-26 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS17035 e71971bcb7425d721552d0e8488cf57e 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 31 77 9.2E-15 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS19635 a1d2af9af524e0710b616016e95e892a 534 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 30 227 3.3E-13 T 06-07-2017 CAK77_RS19635 a1d2af9af524e0710b616016e95e892a 534 Gene3D G3DSA:3.50.50.60 23 228 3.5E-56 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS19635 a1d2af9af524e0710b616016e95e892a 534 Gene3D G3DSA:3.50.50.60 328 505 9.0E-21 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS19635 a1d2af9af524e0710b616016e95e892a 534 SUPERFAMILY SSF51905 314 429 3.29E-49 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS19635 a1d2af9af524e0710b616016e95e892a 534 SUPERFAMILY SSF51905 28 247 3.29E-49 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS10300 1c1f24ba3de2fd0017e48ca9994a1e5b 1010 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 673 851 5.0E-14 T 06-07-2017 CAK77_RS10300 1c1f24ba3de2fd0017e48ca9994a1e5b 1010 SUPERFAMILY SSF55048 204 267 1.18E-7 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CAK77_RS10300 1c1f24ba3de2fd0017e48ca9994a1e5b 1010 SUPERFAMILY SSF47336 939 1008 1.83E-11 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS10300 1c1f24ba3de2fd0017e48ca9994a1e5b 1010 SUPERFAMILY SSF51735 471 658 2.56E-17 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS10300 1c1f24ba3de2fd0017e48ca9994a1e5b 1010 SUPERFAMILY SSF52151 77 204 1.39E-46 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAK77_RS10300 1c1f24ba3de2fd0017e48ca9994a1e5b 1010 SUPERFAMILY SSF52151 269 368 1.39E-46 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAK77_RS10300 1c1f24ba3de2fd0017e48ca9994a1e5b 1010 Gene3D G3DSA:3.40.50.720 670 848 1.2E-27 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS10300 1c1f24ba3de2fd0017e48ca9994a1e5b 1010 SMART SM00823 Phosphopantetheine attachment site 937 1009 7.4E-8 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAK77_RS10300 1c1f24ba3de2fd0017e48ca9994a1e5b 1010 Gene3D G3DSA:3.40.366.10 78 198 2.3E-52 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAK77_RS10300 1c1f24ba3de2fd0017e48ca9994a1e5b 1010 Gene3D G3DSA:3.40.366.10 267 382 2.3E-52 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAK77_RS10300 1c1f24ba3de2fd0017e48ca9994a1e5b 1010 Pfam PF00550 Phosphopantetheine attachment site 940 1004 3.3E-9 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS10300 1c1f24ba3de2fd0017e48ca9994a1e5b 1010 Pfam PF00698 Acyl transferase domain 79 398 5.3E-53 T 06-07-2017 IPR014043 Acyl transferase CAK77_RS10300 1c1f24ba3de2fd0017e48ca9994a1e5b 1010 Gene3D G3DSA:1.10.1200.10 940 1008 2.2E-10 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS10300 1c1f24ba3de2fd0017e48ca9994a1e5b 1010 Gene3D G3DSA:3.30.70.250 206 266 2.9E-4 T 06-07-2017 CAK77_RS10300 1c1f24ba3de2fd0017e48ca9994a1e5b 1010 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 80 383 3.7E-64 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain CAK77_RS10300 1c1f24ba3de2fd0017e48ca9994a1e5b 1010 Pfam PF08659 KR domain 675 849 1.2E-40 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAK77_RS10300 1c1f24ba3de2fd0017e48ca9994a1e5b 1010 SUPERFAMILY SSF51735 673 876 5.84E-33 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS12275 f545802aaabb043923c92080939002ac 488 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 413 467 9.6E-13 T 06-07-2017 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 CAK77_RS12275 f545802aaabb043923c92080939002ac 488 SUPERFAMILY SSF53383 6 382 2.67E-68 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK77_RS12275 f545802aaabb043923c92080939002ac 488 SUPERFAMILY SSF55904 341 486 1.31E-30 T 06-07-2017 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 CAK77_RS12275 f545802aaabb043923c92080939002ac 488 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 6 312 2.3E-44 T 06-07-2017 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 CAK77_RS12275 f545802aaabb043923c92080939002ac 488 Gene3D G3DSA:3.90.100.10 406 486 6.6E-25 T 06-07-2017 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 CAK77_RS12275 f545802aaabb043923c92080939002ac 488 Gene3D G3DSA:3.40.640.10 6 284 1.6E-74 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK77_RS15700 e52c50792536b09b90f452e20f731ab7 453 Hamap MF_00027 Cobyrinate a,c-diamide synthase [cbiA]. 1 431 37.265 T 06-07-2017 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 CAK77_RS15700 e52c50792536b09b90f452e20f731ab7 453 SUPERFAMILY SSF52317 248 438 1.16E-23 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAK77_RS15700 e52c50792536b09b90f452e20f731ab7 453 TIGRFAM TIGR00379 cobB: cobyrinic acid a,c-diamide synthase 1 441 1.8E-101 T 06-07-2017 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 CAK77_RS15700 e52c50792536b09b90f452e20f731ab7 453 Gene3D G3DSA:3.40.50.880 249 442 2.5E-22 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAK77_RS15700 e52c50792536b09b90f452e20f731ab7 453 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 1 188 2.7E-24 T 06-07-2017 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain CAK77_RS15700 e52c50792536b09b90f452e20f731ab7 453 Gene3D G3DSA:3.40.50.300 2 191 1.5E-23 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS15700 e52c50792536b09b90f452e20f731ab7 453 SUPERFAMILY SSF52540 2 192 3.09E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS15700 e52c50792536b09b90f452e20f731ab7 453 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 254 428 1.1E-20 T 06-07-2017 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 CAK77_RS09420 30f3291f9aa333a560ddfc44337be74d 402 Pfam PF00067 Cytochrome P450 253 370 1.3E-17 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS09420 30f3291f9aa333a560ddfc44337be74d 402 SUPERFAMILY SSF48264 7 399 5.24E-75 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS09420 30f3291f9aa333a560ddfc44337be74d 402 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 343 352 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CAK77_RS09420 30f3291f9aa333a560ddfc44337be74d 402 Gene3D G3DSA:1.10.630.10 6 399 1.2E-90 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS09420 30f3291f9aa333a560ddfc44337be74d 402 PRINTS PR00359 B-class P450 signature 88 99 3.3E-36 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS09420 30f3291f9aa333a560ddfc44337be74d 402 PRINTS PR00359 B-class P450 signature 151 166 3.3E-36 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS09420 30f3291f9aa333a560ddfc44337be74d 402 PRINTS PR00359 B-class P450 signature 194 216 3.3E-36 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS09420 30f3291f9aa333a560ddfc44337be74d 402 PRINTS PR00359 B-class P450 signature 319 334 3.3E-36 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS09420 30f3291f9aa333a560ddfc44337be74d 402 PRINTS PR00359 B-class P450 signature 274 285 3.3E-36 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS09420 30f3291f9aa333a560ddfc44337be74d 402 PRINTS PR00359 B-class P450 signature 341 350 3.3E-36 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS09420 30f3291f9aa333a560ddfc44337be74d 402 PRINTS PR00359 B-class P450 signature 350 361 3.3E-36 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS09420 30f3291f9aa333a560ddfc44337be74d 402 PRINTS PR00359 B-class P450 signature 134 150 3.3E-36 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS09420 30f3291f9aa333a560ddfc44337be74d 402 PRINTS PR00359 B-class P450 signature 291 318 3.3E-36 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS16775 70a5d4d1fc834c0939705928889bfc91 278 Pfam PF10118 Predicted metal-dependent hydrolase 6 254 6.5E-74 T 06-07-2017 IPR016516 Uncharacterised conserved protein UCP07580 CAK77_RS16775 70a5d4d1fc834c0939705928889bfc91 278 PIRSF PIRSF007580 1 272 1.0E-69 T 06-07-2017 IPR016516 Uncharacterised conserved protein UCP07580 CAK77_RS00650 52662eca08d5d3d53c53659851686329 197 Gene3D G3DSA:1.10.357.10 9 196 1.2E-18 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS00650 52662eca08d5d3d53c53659851686329 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 58 8.9E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS00650 52662eca08d5d3d53c53659851686329 197 SUPERFAMILY SSF48498 126 191 4.45E-5 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS00650 52662eca08d5d3d53c53659851686329 197 SUPERFAMILY SSF46689 9 78 1.1E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS11695 b02e5124dec7f3dac322a31962a4968a 735 Hamap MF_00641 Malate synthase G [glcB]. 1 735 403.444 T 06-07-2017 IPR006253 Malate synthase G GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 CAK77_RS11695 b02e5124dec7f3dac322a31962a4968a 735 Pfam PF01274 Malate synthase 17 707 1.5E-190 T 06-07-2017 IPR001465 Malate synthase GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 CAK77_RS11695 b02e5124dec7f3dac322a31962a4968a 735 Gene3D G3DSA:3.20.20.360 89 135 1.4E-145 T 06-07-2017 CAK77_RS11695 b02e5124dec7f3dac322a31962a4968a 735 Gene3D G3DSA:3.20.20.360 271 301 1.4E-145 T 06-07-2017 CAK77_RS11695 b02e5124dec7f3dac322a31962a4968a 735 Gene3D G3DSA:3.20.20.360 342 594 1.4E-145 T 06-07-2017 CAK77_RS11695 b02e5124dec7f3dac322a31962a4968a 735 Gene3D G3DSA:1.20.1220.12 600 732 4.1E-72 T 06-07-2017 CAK77_RS11695 b02e5124dec7f3dac322a31962a4968a 735 TIGRFAM TIGR01345 malate_syn_G: malate synthase G 4 731 0.0 T 06-07-2017 IPR006253 Malate synthase G GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 CAK77_RS11695 b02e5124dec7f3dac322a31962a4968a 735 Gene3D G3DSA:1.10.1860.10 1 88 1.3E-35 T 06-07-2017 CAK77_RS11695 b02e5124dec7f3dac322a31962a4968a 735 Gene3D G3DSA:2.170.170.11 136 269 4.5E-64 T 06-07-2017 IPR023310 Malate synthase G, beta sub-domain GO:0004474 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 CAK77_RS11695 b02e5124dec7f3dac322a31962a4968a 735 Gene3D G3DSA:2.170.170.11 303 341 4.5E-64 T 06-07-2017 IPR023310 Malate synthase G, beta sub-domain GO:0004474 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 CAK77_RS11695 b02e5124dec7f3dac322a31962a4968a 735 SUPERFAMILY SSF51645 3 731 1.96E-296 T 06-07-2017 IPR011076 Malate synthase-like GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 CAK77_RS21210 b6e6d86b855f4553188d72f9a59ea98c 453 Gene3D G3DSA:3.20.20.30 15 305 1.5E-116 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS21210 b6e6d86b855f4553188d72f9a59ea98c 453 Gene3D G3DSA:3.20.20.30 355 438 1.5E-116 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS21210 b6e6d86b855f4553188d72f9a59ea98c 453 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 29 434 2.0E-124 T 06-07-2017 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 CAK77_RS21210 b6e6d86b855f4553188d72f9a59ea98c 453 SUPERFAMILY SSF51679 16 438 2.25E-109 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS21210 b6e6d86b855f4553188d72f9a59ea98c 453 PIRSF PIRSF000337 14 447 1.1E-138 T 06-07-2017 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 CAK77_RS21210 b6e6d86b855f4553188d72f9a59ea98c 453 Pfam PF00296 Luciferase-like monooxygenase 38 353 2.2E-60 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS06275 4d1ea53d67eb23114012002d2ba9727f 342 Pfam PF03320 Bacterial fructose-1,6-bisphosphatase, glpX-encoded 11 318 5.2E-142 T 06-07-2017 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 CAK77_RS06275 4d1ea53d67eb23114012002d2ba9727f 342 Gene3D G3DSA:3.30.540.10 182 329 1.3E-46 T 06-07-2017 CAK77_RS06275 4d1ea53d67eb23114012002d2ba9727f 342 Gene3D G3DSA:3.30.540.10 9 181 4.7E-65 T 06-07-2017 CAK77_RS06275 4d1ea53d67eb23114012002d2ba9727f 342 TIGRFAM TIGR00330 glpX: fructose-1,6-bisphosphatase, class II 11 322 1.7E-110 T 06-07-2017 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 CAK77_RS06275 4d1ea53d67eb23114012002d2ba9727f 342 PIRSF PIRSF004532 9 329 8.3E-151 T 06-07-2017 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 CAK77_RS06275 4d1ea53d67eb23114012002d2ba9727f 342 SUPERFAMILY SSF56655 9 321 1.41E-112 T 06-07-2017 CAK77_RS01045 0cc92d1f1a91af7482ffcc9f1faa36fd 333 Gene3D G3DSA:3.40.50.1820 50 330 7.4E-112 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS01045 0cc92d1f1a91af7482ffcc9f1faa36fd 333 Pfam PF00756 Putative esterase 62 326 6.6E-58 T 06-07-2017 IPR000801 Putative esterase Reactome: R-HSA-156590 CAK77_RS01045 0cc92d1f1a91af7482ffcc9f1faa36fd 333 SUPERFAMILY SSF53474 48 330 1.53E-32 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS20885 b230367bf03973efaf38af48ff7d7288 329 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 74 139 5.7E-9 T 06-07-2017 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal CAK77_RS20885 b230367bf03973efaf38af48ff7d7288 329 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 233 297 2.0E-13 T 06-07-2017 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal CAK77_RS20885 b230367bf03973efaf38af48ff7d7288 329 Gene3D G3DSA:2.40.50.140 90 142 4.4E-4 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS20885 b230367bf03973efaf38af48ff7d7288 329 Gene3D G3DSA:2.40.50.140 236 301 2.0E-5 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS20885 b230367bf03973efaf38af48ff7d7288 329 SUPERFAMILY SSF50249 168 303 2.57E-31 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS20885 b230367bf03973efaf38af48ff7d7288 329 SUPERFAMILY SSF50249 13 148 1.47E-25 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS09345 1dbc0fb07fb847c3b67551c2ab3afe9c 167 SUPERFAMILY SSF54427 1 135 3.25E-24 T 06-07-2017 IPR032710 NTF2-like domain CAK77_RS09345 1dbc0fb07fb847c3b67551c2ab3afe9c 167 Gene3D G3DSA:3.10.450.50 10 136 5.8E-14 T 06-07-2017 IPR032710 NTF2-like domain CAK77_RS09345 1dbc0fb07fb847c3b67551c2ab3afe9c 167 Pfam PF12680 SnoaL-like domain 22 104 3.6E-7 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain CAK77_RS19065 c3387694ef986b21283606d8328657c6 217 Pfam PF00297 Ribosomal protein L3 97 187 8.7E-17 T 06-07-2017 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS19065 c3387694ef986b21283606d8328657c6 217 SUPERFAMILY SSF50447 3 215 1.5E-81 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain CAK77_RS19065 c3387694ef986b21283606d8328657c6 217 Gene3D G3DSA:4.10.960.10 78 162 7.4E-35 T 06-07-2017 CAK77_RS19065 c3387694ef986b21283606d8328657c6 217 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 3 212 39.959 T 06-07-2017 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS19065 c3387694ef986b21283606d8328657c6 217 ProSitePatterns PS00474 Ribosomal protein L3 signature. 106 129 - T 06-07-2017 IPR019926 Ribosomal protein L3, conserved site CAK77_RS19065 c3387694ef986b21283606d8328657c6 217 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 5 209 4.0E-88 T 06-07-2017 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS19065 c3387694ef986b21283606d8328657c6 217 Gene3D G3DSA:2.40.30.10 163 214 2.4E-12 T 06-07-2017 CAK77_RS19065 c3387694ef986b21283606d8328657c6 217 Gene3D G3DSA:2.40.30.10 5 34 2.4E-12 T 06-07-2017 CAK77_RS10390 c11ef5500b14ec205a66f8f820876009 432 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 67 78 - T 06-07-2017 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS10390 c11ef5500b14ec205a66f8f820876009 432 Gene3D G3DSA:1.10.645.10 25 257 5.5E-44 T 06-07-2017 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS10390 c11ef5500b14ec205a66f8f820876009 432 Gene3D G3DSA:1.10.645.10 259 316 1.6E-23 T 06-07-2017 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS10390 c11ef5500b14ec205a66f8f820876009 432 Gene3D G3DSA:1.10.645.10 360 425 1.6E-23 T 06-07-2017 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS10390 c11ef5500b14ec205a66f8f820876009 432 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 147 432 1.6E-112 T 06-07-2017 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS10390 c11ef5500b14ec205a66f8f820876009 432 SUPERFAMILY SSF56762 40 432 1.83E-122 T 06-07-2017 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS10390 c11ef5500b14ec205a66f8f820876009 432 TIGRFAM TIGR01962 NuoD: NADH dehydrogenase (quinone), D subunit 30 432 6.2E-180 T 06-07-2017 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS10390 c11ef5500b14ec205a66f8f820876009 432 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 26 432 46.807 T 06-07-2017 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS06410 6929839ad0ef3376e02dc1dadb2c0358 444 SUPERFAMILY SSF52777 26 145 1.0E-4 T 06-07-2017 CAK77_RS06410 6929839ad0ef3376e02dc1dadb2c0358 444 Pfam PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain 22 154 6.2E-6 T 06-07-2017 IPR004255 O-acyltransferase, WSD1, N-terminal GO:0004144|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CAK77_RS15445 c8bb71bff09c871a38fdd50c68841b30 269 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 136 164 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK77_RS15445 c8bb71bff09c871a38fdd50c68841b30 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 3.8E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS15445 c8bb71bff09c871a38fdd50c68841b30 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 168 3.8E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS15445 c8bb71bff09c871a38fdd50c68841b30 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 3.8E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS15445 c8bb71bff09c871a38fdd50c68841b30 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 3.8E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS15445 c8bb71bff09c871a38fdd50c68841b30 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 139 3.8E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS15445 c8bb71bff09c871a38fdd50c68841b30 269 Gene3D G3DSA:3.40.50.720 2 229 6.0E-49 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS15445 c8bb71bff09c871a38fdd50c68841b30 269 Pfam PF00106 short chain dehydrogenase 7 192 3.4E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS15445 c8bb71bff09c871a38fdd50c68841b30 269 SUPERFAMILY SSF51735 1 264 2.07E-50 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS08990 ad4d276781efd7fe3de1657544c9d3e7 362 SMART SM00829 12 362 0.0039 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAK77_RS08990 ad4d276781efd7fe3de1657544c9d3e7 362 SUPERFAMILY SSF51735 154 327 3.48E-43 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS08990 ad4d276781efd7fe3de1657544c9d3e7 362 SUPERFAMILY SSF50129 312 361 2.97E-7 T 06-07-2017 IPR011032 GroES-like CAK77_RS08990 ad4d276781efd7fe3de1657544c9d3e7 362 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 06-07-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CAK77_RS08990 ad4d276781efd7fe3de1657544c9d3e7 362 SUPERFAMILY SSF50129 4 186 6.24E-53 T 06-07-2017 IPR011032 GroES-like CAK77_RS08990 ad4d276781efd7fe3de1657544c9d3e7 362 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 148 2.8E-26 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAK77_RS08990 ad4d276781efd7fe3de1657544c9d3e7 362 Pfam PF00107 Zinc-binding dehydrogenase 190 317 2.3E-26 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAK77_RS08990 ad4d276781efd7fe3de1657544c9d3e7 362 Gene3D G3DSA:3.90.180.10 2 182 6.0E-53 T 06-07-2017 IPR011032 GroES-like CAK77_RS08990 ad4d276781efd7fe3de1657544c9d3e7 362 Gene3D G3DSA:3.40.50.720 183 303 1.6E-41 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS08990 ad4d276781efd7fe3de1657544c9d3e7 362 TIGRFAM TIGR03451 mycoS_dep_FDH: S-(hydroxymethyl)mycothiol dehydrogenase 4 362 6.5E-208 T 06-07-2017 IPR017816 S-(hydroxymethyl)mycothiol dehydrogenase KEGG: 00072+1.1.1.30|KEGG: 00650+1.1.1.30 CAK77_RS06415 915bdb4ea77a21d8ed5a5474b4c8c8c6 171 PIRSF PIRSF021700 8 166 4.8E-65 T 06-07-2017 IPR009725 Predicted 3-demethylubiquinone-9 3-methyltransferase CAK77_RS06415 915bdb4ea77a21d8ed5a5474b4c8c8c6 171 Gene3D G3DSA:3.10.180.10 10 138 7.8E-49 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK77_RS06415 915bdb4ea77a21d8ed5a5474b4c8c8c6 171 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 12 126 9.7E-52 T 06-07-2017 IPR028973 PhnB-like CAK77_RS06415 915bdb4ea77a21d8ed5a5474b4c8c8c6 171 SUPERFAMILY SSF54593 12 163 2.41E-50 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK77_RS20950 d8ee5e6de0e9af27e1098ac641d988d5 307 Gene3D G3DSA:3.30.450.40 245 304 4.2E-17 T 06-07-2017 IPR029016 GAF domain-like CAK77_RS20950 d8ee5e6de0e9af27e1098ac641d988d5 307 Gene3D G3DSA:3.30.450.40 88 194 4.2E-17 T 06-07-2017 IPR029016 GAF domain-like CAK77_RS20950 d8ee5e6de0e9af27e1098ac641d988d5 307 SUPERFAMILY SSF46785 16 88 2.61E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS20950 d8ee5e6de0e9af27e1098ac641d988d5 307 SMART SM00346 13 104 7.8E-13 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAK77_RS20950 d8ee5e6de0e9af27e1098ac641d988d5 307 Pfam PF09339 IclR helix-turn-helix domain 17 66 8.0E-11 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAK77_RS20950 d8ee5e6de0e9af27e1098ac641d988d5 307 Gene3D G3DSA:1.10.10.10 14 87 1.2E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS20950 d8ee5e6de0e9af27e1098ac641d988d5 307 SUPERFAMILY SSF55781 95 195 4.37E-11 T 06-07-2017 IPR029016 GAF domain-like CAK77_RS20950 d8ee5e6de0e9af27e1098ac641d988d5 307 SUPERFAMILY SSF55781 246 302 4.37E-11 T 06-07-2017 IPR029016 GAF domain-like CAK77_RS04475 4d405eabe2282994a5d526071a533968 90 ProDom PD053583 TRANSMEMBRANE MEMBRANE PRECURSOR SIGNAL MB0906 RV0882/MT0905 3 88 5.0E-16 T 06-07-2017 IPR024244 Protein of unknown function DUF2537 CAK77_RS04475 4d405eabe2282994a5d526071a533968 90 Pfam PF10801 Protein of unknown function (DUF2537) 6 85 8.6E-28 T 06-07-2017 IPR024244 Protein of unknown function DUF2537 CAK77_RS21465 f9568331c42f1ba1a7d6c868aab51802 139 SUPERFAMILY SSF46955 24 115 2.2E-20 T 06-07-2017 IPR009061 Putative DNA-binding domain CAK77_RS21465 f9568331c42f1ba1a7d6c868aab51802 139 Gene3D G3DSA:1.10.1660.10 25 115 1.3E-23 T 06-07-2017 CAK77_RS21465 f9568331c42f1ba1a7d6c868aab51802 139 Pfam PF13411 MerR HTH family regulatory protein 25 90 3.3E-17 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAK77_RS21465 f9568331c42f1ba1a7d6c868aab51802 139 SMART SM00422 23 92 2.9E-26 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAK77_RS13650 ce40d64021714e22d57c0fcc499c0bd7 507 SUPERFAMILY SSF53720 13 499 2.62E-161 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAK77_RS13650 ce40d64021714e22d57c0fcc499c0bd7 507 Gene3D G3DSA:3.40.605.10 19 270 7.5E-93 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAK77_RS13650 ce40d64021714e22d57c0fcc499c0bd7 507 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 262 269 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CAK77_RS13650 ce40d64021714e22d57c0fcc499c0bd7 507 Gene3D G3DSA:3.40.309.10 271 470 1.3E-57 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAK77_RS13650 ce40d64021714e22d57c0fcc499c0bd7 507 Pfam PF00171 Aldehyde dehydrogenase family 28 494 3.5E-160 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAK77_RS13650 ce40d64021714e22d57c0fcc499c0bd7 507 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 295 306 - T 06-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CAK77_RS01820 2a38ef3e21ef3dbfdcd692d0300d5f08 208 Pfam PF14032 PknH-like extracellular domain 25 200 4.5E-33 T 06-07-2017 IPR026954 PknH-like extracellular domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 CAK77_RS14905 242784bded9bd05c2f50408511b2eaf7 219 Pfam PF02080 TrkA-C domain 149 212 8.0E-11 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CAK77_RS14905 242784bded9bd05c2f50408511b2eaf7 219 Pfam PF02254 TrkA-N domain 3 118 2.1E-23 T 06-07-2017 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 CAK77_RS14905 242784bded9bd05c2f50408511b2eaf7 219 SUPERFAMILY SSF116726 133 213 1.06E-13 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CAK77_RS14905 242784bded9bd05c2f50408511b2eaf7 219 SUPERFAMILY SSF51735 1 145 6.7E-30 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS14905 242784bded9bd05c2f50408511b2eaf7 219 Gene3D G3DSA:3.40.50.720 1 146 5.2E-31 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS14905 242784bded9bd05c2f50408511b2eaf7 219 Gene3D G3DSA:3.30.70.1450 147 209 4.6E-9 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CAK77_RS14905 242784bded9bd05c2f50408511b2eaf7 219 PRINTS PR00335 TrkA potassium uptake protein signature 48 58 1.2E-7 T 06-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 CAK77_RS14905 242784bded9bd05c2f50408511b2eaf7 219 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 1.2E-7 T 06-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 CAK77_RS14905 242784bded9bd05c2f50408511b2eaf7 219 PRINTS PR00335 TrkA potassium uptake protein signature 72 86 1.2E-7 T 06-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 CAK77_RS14905 242784bded9bd05c2f50408511b2eaf7 219 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 1.2E-7 T 06-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 CAK77_RS06875 9691bcf2d717217c8f9764065d87fc5e 300 SUPERFAMILY SSF161098 13 287 8.24E-49 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS06875 9691bcf2d717217c8f9764065d87fc5e 300 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 283 3.8E-9 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS06875 9691bcf2d717217c8f9764065d87fc5e 300 Gene3D G3DSA:1.10.3720.10 10 283 2.3E-54 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS20295 1a16ece9b6ae551a4d7a5a629cac2793 313 Gene3D G3DSA:1.20.1260.10 45 173 4.8E-6 T 06-07-2017 IPR012347 Ferritin-related CAK77_RS20295 1a16ece9b6ae551a4d7a5a629cac2793 313 SUPERFAMILY SSF47240 10 239 9.92E-38 T 06-07-2017 IPR009078 Ferritin-like superfamily CAK77_RS02970 f3f5459ddedfd2b0e6215d968748e4be 315 SUPERFAMILY SSF55315 68 148 3.65E-15 T 06-07-2017 IPR029064 50S ribosomal protein L30e-like CAK77_RS02970 f3f5459ddedfd2b0e6215d968748e4be 315 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 76 150 1.3E-16 T 06-07-2017 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 CAK77_RS02970 f3f5459ddedfd2b0e6215d968748e4be 315 Pfam PF00588 SpoU rRNA Methylase family 168 307 3.4E-36 T 06-07-2017 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CAK77_RS02970 f3f5459ddedfd2b0e6215d968748e4be 315 Gene3D G3DSA:3.30.1330.30 68 147 5.8E-19 T 06-07-2017 IPR029064 50S ribosomal protein L30e-like CAK77_RS02970 f3f5459ddedfd2b0e6215d968748e4be 315 SMART SM00967 75 151 9.6E-17 T 06-07-2017 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 CAK77_RS02970 f3f5459ddedfd2b0e6215d968748e4be 315 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 74 314 2.2E-61 T 06-07-2017 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 CAK77_RS02970 f3f5459ddedfd2b0e6215d968748e4be 315 SUPERFAMILY SSF75217 139 315 1.44E-43 T 06-07-2017 IPR029028 Alpha/beta knot methyltransferases CAK77_RS02970 f3f5459ddedfd2b0e6215d968748e4be 315 Gene3D G3DSA:3.40.1280.10 163 315 5.4E-50 T 06-07-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CAK77_RS22820 f3fe0ec809387966c776732238e86a38 308 Pfam PF04072 Leucine carboxyl methyltransferase 27 203 9.3E-58 T 06-07-2017 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 CAK77_RS22820 f3fe0ec809387966c776732238e86a38 308 Gene3D G3DSA:3.40.50.150 22 211 2.4E-16 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS22820 f3fe0ec809387966c776732238e86a38 308 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 25 282 7.4E-80 T 06-07-2017 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 CAK77_RS22820 f3fe0ec809387966c776732238e86a38 308 SUPERFAMILY SSF53335 23 291 6.65E-69 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS04220 ac276f2b88b3a4a63c5cc5a7a4e9d6b6 208 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 63 3.9E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS04220 ac276f2b88b3a4a63c5cc5a7a4e9d6b6 208 Gene3D G3DSA:1.10.357.10 77 185 1.3E-9 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS04220 ac276f2b88b3a4a63c5cc5a7a4e9d6b6 208 SUPERFAMILY SSF46689 9 66 4.14E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS04220 ac276f2b88b3a4a63c5cc5a7a4e9d6b6 208 Gene3D G3DSA:1.10.10.60 8 56 6.9E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS04220 ac276f2b88b3a4a63c5cc5a7a4e9d6b6 208 Pfam PF16859 Bacterial transcriptional repressor C-terminal 84 185 8.8E-12 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS04220 ac276f2b88b3a4a63c5cc5a7a4e9d6b6 208 ProSitePatterns PS01081 TetR-type HTH domain signature. 30 61 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CAK77_RS04220 ac276f2b88b3a4a63c5cc5a7a4e9d6b6 208 SUPERFAMILY SSF48498 82 185 1.33E-8 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS14745 9d4dbf0d9ce4575b163ed833c56b03c1 580 SUPERFAMILY SSF51556 368 499 1.17E-38 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK77_RS14745 9d4dbf0d9ce4575b163ed833c56b03c1 580 SUPERFAMILY SSF51556 59 316 1.17E-38 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK77_RS14745 9d4dbf0d9ce4575b163ed833c56b03c1 580 Gene3D G3DSA:3.20.20.140 73 312 1.0E-71 T 06-07-2017 CAK77_RS14745 9d4dbf0d9ce4575b163ed833c56b03c1 580 Gene3D G3DSA:3.20.20.140 423 487 1.0E-71 T 06-07-2017 CAK77_RS14745 9d4dbf0d9ce4575b163ed833c56b03c1 580 Gene3D G3DSA:2.30.40.10 4 72 2.7E-18 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK77_RS14745 9d4dbf0d9ce4575b163ed833c56b03c1 580 Pfam PF07969 Amidohydrolase family 47 202 4.9E-10 T 06-07-2017 IPR013108 Amidohydrolase 3 CAK77_RS14745 9d4dbf0d9ce4575b163ed833c56b03c1 580 Gene3D G3DSA:2.30.40.10 488 575 5.0E-10 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK77_RS14745 9d4dbf0d9ce4575b163ed833c56b03c1 580 SUPERFAMILY SSF51338 4 58 4.32E-19 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK77_RS14745 9d4dbf0d9ce4575b163ed833c56b03c1 580 SUPERFAMILY SSF51338 501 565 4.32E-19 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK77_RS01480 d6ad1f4227fdc8f7c0e82b6377415fda 521 Gene3D G3DSA:2.30.38.10 349 423 4.1E-12 T 06-07-2017 CAK77_RS01480 d6ad1f4227fdc8f7c0e82b6377415fda 521 ProSitePatterns PS00455 Putative AMP-binding domain signature. 178 189 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK77_RS01480 d6ad1f4227fdc8f7c0e82b6377415fda 521 Gene3D G3DSA:3.40.50.980 14 183 1.1E-22 T 06-07-2017 CAK77_RS01480 d6ad1f4227fdc8f7c0e82b6377415fda 521 Pfam PF00501 AMP-binding enzyme 17 428 4.3E-46 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK77_RS01480 d6ad1f4227fdc8f7c0e82b6377415fda 521 SUPERFAMILY SSF56801 13 515 1.96E-62 T 06-07-2017 CAK77_RS01480 d6ad1f4227fdc8f7c0e82b6377415fda 521 Gene3D G3DSA:3.40.50.980 184 332 1.4E-10 T 06-07-2017 CAK77_RS18130 c752d853988c8b3edd9fad27efd54701 298 SMART SM00450 158 284 1.5E-19 T 06-07-2017 IPR001763 Rhodanese-like domain CAK77_RS18130 c752d853988c8b3edd9fad27efd54701 298 SMART SM00450 21 135 2.9E-17 T 06-07-2017 IPR001763 Rhodanese-like domain CAK77_RS18130 c752d853988c8b3edd9fad27efd54701 298 ProSitePatterns PS00683 Rhodanese C-terminal signature. 268 278 - T 06-07-2017 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 CAK77_RS18130 c752d853988c8b3edd9fad27efd54701 298 Gene3D G3DSA:3.40.250.10 160 289 5.2E-33 T 06-07-2017 IPR001763 Rhodanese-like domain CAK77_RS18130 c752d853988c8b3edd9fad27efd54701 298 SUPERFAMILY SSF52821 161 289 4.58E-31 T 06-07-2017 IPR001763 Rhodanese-like domain CAK77_RS18130 c752d853988c8b3edd9fad27efd54701 298 Pfam PF00581 Rhodanese-like domain 22 131 1.7E-12 T 06-07-2017 IPR001763 Rhodanese-like domain CAK77_RS18130 c752d853988c8b3edd9fad27efd54701 298 Pfam PF00581 Rhodanese-like domain 163 279 2.3E-14 T 06-07-2017 IPR001763 Rhodanese-like domain CAK77_RS18130 c752d853988c8b3edd9fad27efd54701 298 SUPERFAMILY SSF52821 14 151 1.96E-33 T 06-07-2017 IPR001763 Rhodanese-like domain CAK77_RS18130 c752d853988c8b3edd9fad27efd54701 298 Gene3D G3DSA:3.40.250.10 14 145 1.5E-31 T 06-07-2017 IPR001763 Rhodanese-like domain CAK77_RS18130 c752d853988c8b3edd9fad27efd54701 298 ProSitePatterns PS00380 Rhodanese signature 1. 47 58 - T 06-07-2017 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 CAK77_RS08520 23156bd199e3982be6b91aa15d98dc4b 304 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 10 167 8.1E-17 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 CAK77_RS08520 23156bd199e3982be6b91aa15d98dc4b 304 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 102 3.6E-6 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 CAK77_RS08520 23156bd199e3982be6b91aa15d98dc4b 304 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 11 31 3.6E-6 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 CAK77_RS08520 23156bd199e3982be6b91aa15d98dc4b 304 SUPERFAMILY SSF54814 185 304 2.26E-36 T 06-07-2017 IPR009019 K homology domain, prokaryotic type GO:0003723 CAK77_RS08520 23156bd199e3982be6b91aa15d98dc4b 304 Hamap MF_00367 GTPase Era [era]. 6 304 34.348 T 06-07-2017 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 CAK77_RS08520 23156bd199e3982be6b91aa15d98dc4b 304 Pfam PF01926 50S ribosome-binding GTPase 11 111 3.3E-20 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 CAK77_RS08520 23156bd199e3982be6b91aa15d98dc4b 304 Gene3D G3DSA:3.30.300.20 191 300 1.9E-37 T 06-07-2017 IPR015946 K homology domain-like, alpha/beta CAK77_RS08520 23156bd199e3982be6b91aa15d98dc4b 304 Gene3D G3DSA:3.40.50.300 4 175 1.2E-38 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS08520 23156bd199e3982be6b91aa15d98dc4b 304 SUPERFAMILY SSF52540 11 215 2.66E-38 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS08520 23156bd199e3982be6b91aa15d98dc4b 304 Pfam PF07650 KH domain 211 293 2.3E-19 T 06-07-2017 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK77_RS08520 23156bd199e3982be6b91aa15d98dc4b 304 TIGRFAM TIGR00436 era: GTP-binding protein Era 9 287 1.1E-69 T 06-07-2017 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 CAK77_RS10950 1eb6d2c1396d7b302d51444ef0d71de4 315 SUPERFAMILY SSF52833 151 311 1.7E-26 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK77_RS10950 1eb6d2c1396d7b302d51444ef0d71de4 315 Gene3D G3DSA:3.40.30.10 151 310 3.3E-20 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK77_RS10950 1eb6d2c1396d7b302d51444ef0d71de4 315 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 3.5E-7 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAK77_RS10950 1eb6d2c1396d7b302d51444ef0d71de4 315 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 3.5E-7 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAK77_RS10950 1eb6d2c1396d7b302d51444ef0d71de4 315 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 3.5E-7 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAK77_RS10950 1eb6d2c1396d7b302d51444ef0d71de4 315 Pfam PF08534 Redoxin 152 304 1.5E-16 T 06-07-2017 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 CAK77_RS10950 1eb6d2c1396d7b302d51444ef0d71de4 315 SMART SM00422 1 69 9.7E-19 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAK77_RS10950 1eb6d2c1396d7b302d51444ef0d71de4 315 SUPERFAMILY SSF46955 1 113 3.44E-21 T 06-07-2017 IPR009061 Putative DNA-binding domain CAK77_RS10950 1eb6d2c1396d7b302d51444ef0d71de4 315 Pfam PF13411 MerR HTH family regulatory protein 1 60 4.5E-14 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAK77_RS10950 1eb6d2c1396d7b302d51444ef0d71de4 315 Gene3D G3DSA:1.10.1660.10 1 116 4.3E-25 T 06-07-2017 CAK77_RS10950 1eb6d2c1396d7b302d51444ef0d71de4 315 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAK77_RS01115 f5f4cdfcc0ebcca62f9e3a54e95d3df2 630 Pfam PF12250 Arabinofuranosyltransferase N terminal 20 446 8.2E-168 T 06-07-2017 IPR020963 Arabinofuranosyltransferase AftA, N-terminal GO:0005886|GO:0016021|GO:0016757|GO:0044038 CAK77_RS01115 f5f4cdfcc0ebcca62f9e3a54e95d3df2 630 Pfam PF12249 Arabinofuranosyltransferase A C terminal 454 625 2.3E-72 T 06-07-2017 IPR020959 Arabinofuranosyltransferase AftA, C-terminal GO:0005886|GO:0016021|GO:0016757|GO:0044038 CAK77_RS06915 94e13f3c7d363c71ae7470d2f714f1b8 295 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 1.6E-21 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06915 94e13f3c7d363c71ae7470d2f714f1b8 295 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 1.6E-21 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06915 94e13f3c7d363c71ae7470d2f714f1b8 295 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.6E-21 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06915 94e13f3c7d363c71ae7470d2f714f1b8 295 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 1.6E-21 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06915 94e13f3c7d363c71ae7470d2f714f1b8 295 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 1.6E-21 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06915 94e13f3c7d363c71ae7470d2f714f1b8 295 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK77_RS06915 94e13f3c7d363c71ae7470d2f714f1b8 295 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 1.4E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06915 94e13f3c7d363c71ae7470d2f714f1b8 295 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 1.4E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06915 94e13f3c7d363c71ae7470d2f714f1b8 295 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 1.4E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06915 94e13f3c7d363c71ae7470d2f714f1b8 295 Gene3D G3DSA:3.40.50.720 5 259 1.8E-63 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS06915 94e13f3c7d363c71ae7470d2f714f1b8 295 Pfam PF00106 short chain dehydrogenase 6 195 5.2E-48 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06915 94e13f3c7d363c71ae7470d2f714f1b8 295 SUPERFAMILY SSF51735 1 269 1.68E-61 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS03890 bad2f63ec62af4d1ea7f329213a974df 471 ProSitePatterns PS00571 Amidases signature. 158 189 - T 06-07-2017 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 CAK77_RS03890 bad2f63ec62af4d1ea7f329213a974df 471 Gene3D G3DSA:3.90.1300.10 8 466 1.0E-102 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAK77_RS03890 bad2f63ec62af4d1ea7f329213a974df 471 SUPERFAMILY SSF75304 5 464 3.53E-103 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAK77_RS03890 bad2f63ec62af4d1ea7f329213a974df 471 Pfam PF01425 Amidase 35 455 1.7E-85 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAK77_RS09630 524db196ddfd8516d5328d9a750e07b2 146 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 4 143 1.6E-16 T 06-07-2017 IPR019587 Polyketide cyclase/dehydrase CAK77_RS09630 524db196ddfd8516d5328d9a750e07b2 146 SUPERFAMILY SSF55961 4 144 2.98E-32 T 06-07-2017 CAK77_RS09630 524db196ddfd8516d5328d9a750e07b2 146 Gene3D G3DSA:3.30.530.20 4 143 2.8E-20 T 06-07-2017 IPR023393 START-like domain CAK77_RS04595 a63732cce3fa4cf1b376b1986781b10a 583 Pfam PF00501 AMP-binding enzyme 17 471 2.1E-65 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK77_RS04595 a63732cce3fa4cf1b376b1986781b10a 583 Gene3D G3DSA:2.30.38.10 387 461 1.0E-15 T 06-07-2017 CAK77_RS04595 a63732cce3fa4cf1b376b1986781b10a 583 Gene3D G3DSA:3.40.50.980 179 348 2.1E-23 T 06-07-2017 CAK77_RS04595 a63732cce3fa4cf1b376b1986781b10a 583 Gene3D G3DSA:3.30.300.30 462 562 4.2E-17 T 06-07-2017 CAK77_RS04595 a63732cce3fa4cf1b376b1986781b10a 583 Gene3D G3DSA:3.40.50.980 7 178 2.0E-25 T 06-07-2017 CAK77_RS04595 a63732cce3fa4cf1b376b1986781b10a 583 SUPERFAMILY SSF56801 7 569 4.32E-92 T 06-07-2017 CAK77_RS15215 defd4c3a531eb09782a77e985c870fd8 153 SUPERFAMILY SSF54593 12 136 6.58E-27 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK77_RS15215 defd4c3a531eb09782a77e985c870fd8 153 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 12 131 4.8E-13 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CAK77_RS15215 defd4c3a531eb09782a77e985c870fd8 153 Gene3D G3DSA:3.10.180.10 13 133 9.2E-28 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK77_RS15215 defd4c3a531eb09782a77e985c870fd8 153 ProSitePatterns PS00934 Glyoxalase I signature 1. 13 34 - T 06-07-2017 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 CAK77_RS02845 7bd5a55182f949f3cfdb63623ace8e50 330 Gene3D G3DSA:3.40.50.1980 191 325 1.1E-27 T 06-07-2017 CAK77_RS02845 7bd5a55182f949f3cfdb63623ace8e50 330 Pfam PF01497 Periplasmic binding protein 49 304 5.8E-27 T 06-07-2017 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CAK77_RS02845 7bd5a55182f949f3cfdb63623ace8e50 330 SUPERFAMILY SSF53807 45 325 9.42E-42 T 06-07-2017 CAK77_RS02845 7bd5a55182f949f3cfdb63623ace8e50 330 Gene3D G3DSA:3.40.50.1980 46 188 8.4E-10 T 06-07-2017 CAK77_RS10020 d31d6ca7a61554b439aa0c86d5e76491 517 Gene3D G3DSA:3.30.300.30 407 506 6.9E-33 T 06-07-2017 CAK77_RS10020 d31d6ca7a61554b439aa0c86d5e76491 517 Gene3D G3DSA:2.30.38.10 333 403 3.9E-27 T 06-07-2017 CAK77_RS10020 d31d6ca7a61554b439aa0c86d5e76491 517 Gene3D G3DSA:3.40.50.980 172 332 1.4E-45 T 06-07-2017 CAK77_RS10020 d31d6ca7a61554b439aa0c86d5e76491 517 Gene3D G3DSA:3.40.50.980 7 171 1.9E-41 T 06-07-2017 CAK77_RS10020 d31d6ca7a61554b439aa0c86d5e76491 517 ProSitePatterns PS00455 Putative AMP-binding domain signature. 166 177 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK77_RS10020 d31d6ca7a61554b439aa0c86d5e76491 517 Pfam PF13193 AMP-binding enzyme C-terminal domain 421 497 1.4E-23 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAK77_RS10020 d31d6ca7a61554b439aa0c86d5e76491 517 Pfam PF00501 AMP-binding enzyme 16 412 9.4E-108 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK77_RS10020 d31d6ca7a61554b439aa0c86d5e76491 517 SUPERFAMILY SSF56801 5 509 7.06E-160 T 06-07-2017 CAK77_RS15975 7f49d60938d277cfefa0d8f3ac9f9547 205 SUPERFAMILY SSF53056 3 198 5.49E-50 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CAK77_RS15975 7f49d60938d277cfefa0d8f3ac9f9547 205 ProSitePatterns PS00704 Prokaryotic-type carbonic anhydrases signature 1. 50 57 - T 06-07-2017 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CAK77_RS15975 7f49d60938d277cfefa0d8f3ac9f9547 205 Pfam PF00484 Carbonic anhydrase 46 193 4.8E-35 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CAK77_RS15975 7f49d60938d277cfefa0d8f3ac9f9547 205 SMART SM00947 38 197 3.5E-45 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CAK77_RS15975 7f49d60938d277cfefa0d8f3ac9f9547 205 Gene3D G3DSA:3.40.1050.10 3 196 1.7E-49 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CAK77_RS23660 418707a31d0309bef3e6396310d1207d 198 Gene3D G3DSA:1.10.357.10 64 197 2.1E-38 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS23660 418707a31d0309bef3e6396310d1207d 198 Pfam PF16859 Bacterial transcriptional repressor C-terminal 81 191 3.4E-29 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS23660 418707a31d0309bef3e6396310d1207d 198 Gene3D G3DSA:1.10.10.60 8 63 1.6E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS23660 418707a31d0309bef3e6396310d1207d 198 SUPERFAMILY SSF46689 12 72 4.85E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS23660 418707a31d0309bef3e6396310d1207d 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 67 6.3E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS23660 418707a31d0309bef3e6396310d1207d 198 SUPERFAMILY SSF48498 84 196 3.86E-26 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS22935 5e8c7316e0410c0b49945f6c450c2a97 419 Gene3D G3DSA:3.40.47.10 16 270 1.4E-55 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS22935 5e8c7316e0410c0b49945f6c450c2a97 419 Gene3D G3DSA:3.40.47.10 274 419 2.4E-50 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS22935 5e8c7316e0410c0b49945f6c450c2a97 419 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 13 257 1.3E-51 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAK77_RS22935 5e8c7316e0410c0b49945f6c450c2a97 419 SUPERFAMILY SSF53901 225 419 1.31E-62 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS22935 5e8c7316e0410c0b49945f6c450c2a97 419 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 164 180 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site CAK77_RS22935 5e8c7316e0410c0b49945f6c450c2a97 419 SUPERFAMILY SSF53901 13 262 1.18E-57 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS22935 5e8c7316e0410c0b49945f6c450c2a97 419 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 265 376 5.7E-29 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAK77_RS22935 5e8c7316e0410c0b49945f6c450c2a97 419 SMART SM00825 Beta-ketoacyl synthase 14 410 1.1E-12 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAK77_RS13580 1f0ed4a109e8b443bdbc6e956a2a6640 412 SUPERFAMILY SSF53748 7 412 2.24E-131 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK77_RS13580 1f0ed4a109e8b443bdbc6e956a2a6640 412 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 18 28 - T 06-07-2017 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK77_RS13580 1f0ed4a109e8b443bdbc6e956a2a6640 412 PIRSF PIRSF000724 1 412 2.7E-122 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK77_RS13580 1f0ed4a109e8b443bdbc6e956a2a6640 412 Gene3D G3DSA:3.40.50.1260 8 197 6.7E-53 T 06-07-2017 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK77_RS13580 1f0ed4a109e8b443bdbc6e956a2a6640 412 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 5 412 38.386 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK77_RS13580 1f0ed4a109e8b443bdbc6e956a2a6640 412 Pfam PF00162 Phosphoglycerate kinase 14 402 5.5E-133 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK77_RS13580 1f0ed4a109e8b443bdbc6e956a2a6640 412 PRINTS PR00477 Phosphoglycerate kinase family signature 13 29 6.6E-64 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK77_RS13580 1f0ed4a109e8b443bdbc6e956a2a6640 412 PRINTS PR00477 Phosphoglycerate kinase family signature 186 208 6.6E-64 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK77_RS13580 1f0ed4a109e8b443bdbc6e956a2a6640 412 PRINTS PR00477 Phosphoglycerate kinase family signature 117 132 6.6E-64 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK77_RS13580 1f0ed4a109e8b443bdbc6e956a2a6640 412 PRINTS PR00477 Phosphoglycerate kinase family signature 156 178 6.6E-64 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK77_RS13580 1f0ed4a109e8b443bdbc6e956a2a6640 412 PRINTS PR00477 Phosphoglycerate kinase family signature 209 228 6.6E-64 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK77_RS13580 1f0ed4a109e8b443bdbc6e956a2a6640 412 PRINTS PR00477 Phosphoglycerate kinase family signature 364 375 6.6E-64 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK77_RS13580 1f0ed4a109e8b443bdbc6e956a2a6640 412 PRINTS PR00477 Phosphoglycerate kinase family signature 388 405 6.6E-64 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK77_RS13580 1f0ed4a109e8b443bdbc6e956a2a6640 412 PRINTS PR00477 Phosphoglycerate kinase family signature 328 353 6.6E-64 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK77_RS13580 1f0ed4a109e8b443bdbc6e956a2a6640 412 Gene3D G3DSA:3.40.50.1270 198 400 1.7E-78 T 06-07-2017 IPR015901 Phosphoglycerate kinase, C-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK77_RS11315 9b9d93a271600974ddc2b0b39c623583 318 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 157 3.8E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS11315 9b9d93a271600974ddc2b0b39c623583 318 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 184 203 3.8E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS11315 9b9d93a271600974ddc2b0b39c623583 318 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 98 109 3.8E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS11315 9b9d93a271600974ddc2b0b39c623583 318 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 22 39 4.3E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS11315 9b9d93a271600974ddc2b0b39c623583 318 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 98 109 4.3E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS11315 9b9d93a271600974ddc2b0b39c623583 318 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 143 159 4.3E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS11315 9b9d93a271600974ddc2b0b39c623583 318 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 184 203 4.3E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS11315 9b9d93a271600974ddc2b0b39c623583 318 Gene3D G3DSA:3.40.50.720 7 232 3.7E-53 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS11315 9b9d93a271600974ddc2b0b39c623583 318 Pfam PF00106 short chain dehydrogenase 22 164 3.4E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS11315 9b9d93a271600974ddc2b0b39c623583 318 SUPERFAMILY SSF51735 15 262 6.24E-50 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS03175 3833ebfa5cf4be0125478a4d0c23af6e 419 Gene3D G3DSA:1.10.630.10 6 410 1.8E-108 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS03175 3833ebfa5cf4be0125478a4d0c23af6e 419 SUPERFAMILY SSF48264 21 409 6.16E-79 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS03175 3833ebfa5cf4be0125478a4d0c23af6e 419 Pfam PF00067 Cytochrome P450 288 377 8.2E-14 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS03175 3833ebfa5cf4be0125478a4d0c23af6e 419 PRINTS PR00359 B-class P450 signature 102 113 3.3E-45 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS03175 3833ebfa5cf4be0125478a4d0c23af6e 419 PRINTS PR00359 B-class P450 signature 302 329 3.3E-45 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS03175 3833ebfa5cf4be0125478a4d0c23af6e 419 PRINTS PR00359 B-class P450 signature 165 180 3.3E-45 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS03175 3833ebfa5cf4be0125478a4d0c23af6e 419 PRINTS PR00359 B-class P450 signature 205 227 3.3E-45 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS03175 3833ebfa5cf4be0125478a4d0c23af6e 419 PRINTS PR00359 B-class P450 signature 352 361 3.3E-45 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS03175 3833ebfa5cf4be0125478a4d0c23af6e 419 PRINTS PR00359 B-class P450 signature 285 296 3.3E-45 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS03175 3833ebfa5cf4be0125478a4d0c23af6e 419 PRINTS PR00359 B-class P450 signature 330 345 3.3E-45 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS03175 3833ebfa5cf4be0125478a4d0c23af6e 419 PRINTS PR00359 B-class P450 signature 148 164 3.3E-45 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS03175 3833ebfa5cf4be0125478a4d0c23af6e 419 PRINTS PR00359 B-class P450 signature 361 372 3.3E-45 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS21810 9a89b9a0c07e367ddf80b8ff9e8a6ef2 320 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 198 220 - T 06-07-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CAK77_RS21810 9a89b9a0c07e367ddf80b8ff9e8a6ef2 320 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 116 287 6.3E-50 T 06-07-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CAK77_RS21810 9a89b9a0c07e367ddf80b8ff9e8a6ef2 320 SUPERFAMILY SSF51735 109 288 4.99E-47 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS21810 9a89b9a0c07e367ddf80b8ff9e8a6ef2 320 Gene3D G3DSA:3.40.50.720 14 122 4.2E-23 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS21810 9a89b9a0c07e367ddf80b8ff9e8a6ef2 320 SUPERFAMILY SSF52283 11 140 8.69E-23 T 06-07-2017 CAK77_RS21810 9a89b9a0c07e367ddf80b8ff9e8a6ef2 320 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 31 319 3.3E-18 T 06-07-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CAK77_RS21810 9a89b9a0c07e367ddf80b8ff9e8a6ef2 320 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 227 243 - T 06-07-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CAK77_RS21810 9a89b9a0c07e367ddf80b8ff9e8a6ef2 320 Gene3D G3DSA:3.40.50.720 123 291 3.0E-52 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS04800 d51859066f117d5f9ef7df7b3164a991 260 SUPERFAMILY SSF54593 11 183 3.43E-25 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK77_RS04800 d51859066f117d5f9ef7df7b3164a991 260 Gene3D G3DSA:3.10.180.10 12 125 3.6E-35 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK77_RS04800 d51859066f117d5f9ef7df7b3164a991 260 Gene3D G3DSA:3.10.180.10 140 257 1.2E-29 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK77_RS04800 d51859066f117d5f9ef7df7b3164a991 260 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 145 254 1.5E-6 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CAK77_RS04800 d51859066f117d5f9ef7df7b3164a991 260 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 15 120 9.3E-8 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CAK77_RS04800 d51859066f117d5f9ef7df7b3164a991 260 SUPERFAMILY SSF54593 142 257 7.44E-16 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK77_RS11195 36f4db65a1480ee866ae4b490dcf8223 984 Gene3D G3DSA:1.20.1640.10 742 940 9.4E-26 T 06-07-2017 CAK77_RS11195 36f4db65a1480ee866ae4b490dcf8223 984 Gene3D G3DSA:1.20.1640.10 156 366 5.1E-29 T 06-07-2017 CAK77_RS11195 36f4db65a1480ee866ae4b490dcf8223 984 SUPERFAMILY SSF82866 158 361 3.4E-28 T 06-07-2017 CAK77_RS11195 36f4db65a1480ee866ae4b490dcf8223 984 SUPERFAMILY SSF82866 731 940 6.28E-32 T 06-07-2017 CAK77_RS11195 36f4db65a1480ee866ae4b490dcf8223 984 Pfam PF03176 MMPL family 55 393 1.5E-109 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 CAK77_RS11195 36f4db65a1480ee866ae4b490dcf8223 984 Pfam PF03176 MMPL family 615 949 7.6E-106 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 CAK77_RS11195 36f4db65a1480ee866ae4b490dcf8223 984 TIGRFAM TIGR00833 actII: transport protein 22 940 0.0 T 06-07-2017 IPR004707 Membrane transport protein MmpL family GO:0016021 CAK77_RS15380 ba367972a18a9e51c288f4f63a343915 163 PIRSF PIRSF000194 1 162 2.3E-49 T 06-07-2017 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CAK77_RS15380 ba367972a18a9e51c288f4f63a343915 163 SUPERFAMILY SSF53597 5 161 5.29E-50 T 06-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CAK77_RS15380 ba367972a18a9e51c288f4f63a343915 163 Gene3D G3DSA:3.40.430.10 4 160 4.8E-51 T 06-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CAK77_RS15380 ba367972a18a9e51c288f4f63a343915 163 PRINTS PR00070 Dihydrofolate reductase signature 16 26 1.3E-14 T 06-07-2017 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CAK77_RS15380 ba367972a18a9e51c288f4f63a343915 163 PRINTS PR00070 Dihydrofolate reductase signature 43 54 1.3E-14 T 06-07-2017 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CAK77_RS15380 ba367972a18a9e51c288f4f63a343915 163 PRINTS PR00070 Dihydrofolate reductase signature 95 109 1.3E-14 T 06-07-2017 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CAK77_RS15380 ba367972a18a9e51c288f4f63a343915 163 PRINTS PR00070 Dihydrofolate reductase signature 30 38 1.3E-14 T 06-07-2017 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CAK77_RS15380 ba367972a18a9e51c288f4f63a343915 163 ProSitePatterns PS00075 Dihydrofolate reductase (DHFR) domain signature. 16 38 - T 06-07-2017 IPR017925 Dihydrofolate reductase conserved site GO:0004146|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-113510|Reactome: R-HSA-1474151|Reactome: R-HSA-196757|Reactome: R-HSA-69205 CAK77_RS15380 ba367972a18a9e51c288f4f63a343915 163 Pfam PF00186 Dihydrofolate reductase 5 160 7.2E-47 T 06-07-2017 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0006545|GO:0009165|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CAK77_RS20745 ef46b1511324d65f23d5e7ec9216b932 112 Pfam PF12840 Helix-turn-helix domain 3 57 1.4E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS20745 ef46b1511324d65f23d5e7ec9216b932 112 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 36 51 2.6E-10 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK77_RS20745 ef46b1511324d65f23d5e7ec9216b932 112 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 4 19 2.6E-10 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK77_RS20745 ef46b1511324d65f23d5e7ec9216b932 112 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 51 66 2.6E-10 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK77_RS20745 ef46b1511324d65f23d5e7ec9216b932 112 SUPERFAMILY SSF46785 2 92 6.63E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS20745 ef46b1511324d65f23d5e7ec9216b932 112 SMART SM00418 2 80 3.8E-18 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK77_RS20745 ef46b1511324d65f23d5e7ec9216b932 112 Gene3D G3DSA:1.10.10.10 2 94 2.0E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS10460 5c7aeb603d547cd55b3e0e2f21eef788 199 SUPERFAMILY SSF48498 74 196 1.03E-17 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS10460 5c7aeb603d547cd55b3e0e2f21eef788 199 Gene3D G3DSA:1.10.357.10 63 195 6.5E-24 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS10460 5c7aeb603d547cd55b3e0e2f21eef788 199 SUPERFAMILY SSF46689 5 67 4.05E-8 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS10460 5c7aeb603d547cd55b3e0e2f21eef788 199 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 73 157 3.5E-16 T 06-07-2017 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 CAK77_RS10460 5c7aeb603d547cd55b3e0e2f21eef788 199 Gene3D G3DSA:1.10.10.60 4 62 2.7E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS07880 fb8e0290e96a549c2f5f24743d51cabb 151 SUPERFAMILY SSF54637 18 148 2.17E-23 T 06-07-2017 IPR029069 HotDog domain CAK77_RS07880 fb8e0290e96a549c2f5f24743d51cabb 151 Gene3D G3DSA:3.10.129.10 12 149 1.0E-34 T 06-07-2017 IPR029069 HotDog domain CAK77_RS07880 fb8e0290e96a549c2f5f24743d51cabb 151 Pfam PF13279 Thioesterase-like superfamily 24 129 3.9E-13 T 06-07-2017 CAK77_RS15280 97ce12a124d80f7352b5592e39804427 294 SMART SM00530 22 94 7.6E-6 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAK77_RS15280 97ce12a124d80f7352b5592e39804427 294 Gene3D G3DSA:1.10.260.40 19 93 3.5E-13 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK77_RS15280 97ce12a124d80f7352b5592e39804427 294 SUPERFAMILY SSF47413 41 93 1.86E-6 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK77_RS15280 97ce12a124d80f7352b5592e39804427 294 Pfam PF13560 Helix-turn-helix domain 19 97 9.3E-15 T 06-07-2017 CAK77_RS21145 39b7e142af29fc20859fd562f767c652 223 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 12 215 5.4E-61 T 06-07-2017 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CAK77_RS21145 39b7e142af29fc20859fd562f767c652 223 Gene3D G3DSA:3.20.20.70 7 219 1.2E-69 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK77_RS21145 39b7e142af29fc20859fd562f767c652 223 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 11 221 24.379 T 06-07-2017 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CAK77_RS21145 39b7e142af29fc20859fd562f767c652 223 SUPERFAMILY SSF51391 6 218 1.24E-58 T 06-07-2017 IPR022998 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CAK77_RS21145 39b7e142af29fc20859fd562f767c652 223 Pfam PF02581 Thiamine monophosphate synthase/TENI 13 203 6.7E-53 T 06-07-2017 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CAK77_RS03100 cedf4832f7726e6c58fedf52b3da3c88 262 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 26 257 3.4E-56 T 06-07-2017 CAK77_RS03100 cedf4832f7726e6c58fedf52b3da3c88 262 Gene3D G3DSA:3.40.50.720 16 258 1.6E-71 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS03100 cedf4832f7726e6c58fedf52b3da3c88 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 96 107 4.8E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS03100 cedf4832f7726e6c58fedf52b3da3c88 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 158 4.8E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS03100 cedf4832f7726e6c58fedf52b3da3c88 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 170 189 4.8E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS03100 cedf4832f7726e6c58fedf52b3da3c88 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 21 38 1.4E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS03100 cedf4832f7726e6c58fedf52b3da3c88 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 160 1.4E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS03100 cedf4832f7726e6c58fedf52b3da3c88 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 191 208 1.4E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS03100 cedf4832f7726e6c58fedf52b3da3c88 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 96 107 1.4E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS03100 cedf4832f7726e6c58fedf52b3da3c88 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 189 1.4E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS03100 cedf4832f7726e6c58fedf52b3da3c88 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 225 245 1.4E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS03100 cedf4832f7726e6c58fedf52b3da3c88 262 SUPERFAMILY SSF51735 17 258 5.89E-68 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS15985 756cd34e38aab74be6d6d353e8662700 499 SMART SM00382 210 392 4.1E-7 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS15985 756cd34e38aab74be6d6d353e8662700 499 Gene3D G3DSA:3.30.230.10 3 168 1.2E-38 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CAK77_RS15985 756cd34e38aab74be6d6d353e8662700 499 TIGRFAM TIGR00368 TIGR00368: Mg chelatase-like protein 7 496 6.7E-141 T 06-07-2017 IPR004482 Mg chelatase-related protein CAK77_RS15985 756cd34e38aab74be6d6d353e8662700 499 SUPERFAMILY SSF52540 190 494 9.15E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS15985 756cd34e38aab74be6d6d353e8662700 499 Pfam PF01078 Magnesium chelatase, subunit ChlI 190 394 7.7E-85 T 06-07-2017 IPR000523 Magnesium chelatase ChlI domain CAK77_RS15985 756cd34e38aab74be6d6d353e8662700 499 Pfam PF13335 Magnesium chelatase, subunit ChlI C-terminal 401 496 2.6E-22 T 06-07-2017 IPR025158 Mg chelatase-related protein, C-terminal domain CAK77_RS15985 756cd34e38aab74be6d6d353e8662700 499 Gene3D G3DSA:3.40.50.300 189 386 5.5E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS15985 756cd34e38aab74be6d6d353e8662700 499 SUPERFAMILY SSF54211 4 168 8.34E-35 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAK77_RS15985 756cd34e38aab74be6d6d353e8662700 499 Pfam PF13541 Subunit ChlI of Mg-chelatase 21 143 2.6E-38 T 06-07-2017 CAK77_RS17690 c61c9f27f9b257f3b234b9de05992f12 406 SUPERFAMILY SSF50998 25 157 1.29E-5 T 06-07-2017 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily CAK77_RS17690 c61c9f27f9b257f3b234b9de05992f12 406 Gene3D G3DSA:2.140.10.10 64 145 8.6E-4 T 06-07-2017 IPR027295 Quinoprotein alcohol dehydrogenase-like domain CAK77_RS02275 6469c78da472a93e854bb8f2283427a1 373 SUPERFAMILY SSF52540 225 289 3.77E-33 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS02275 6469c78da472a93e854bb8f2283427a1 373 SUPERFAMILY SSF52540 16 187 3.77E-33 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS02275 6469c78da472a93e854bb8f2283427a1 373 Gene3D G3DSA:3.40.50.300 212 289 9.3E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS02275 6469c78da472a93e854bb8f2283427a1 373 Gene3D G3DSA:3.40.50.300 14 175 9.3E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS02275 6469c78da472a93e854bb8f2283427a1 373 Pfam PF02374 Anion-transporting ATPase 20 286 1.7E-27 T 06-07-2017 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 CAK77_RS16335 3e786c870aee493883735e64eb737079 255 Gene3D G3DSA:3.90.226.10 8 254 1.8E-54 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS16335 3e786c870aee493883735e64eb737079 255 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 254 7.0E-41 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAK77_RS16335 3e786c870aee493883735e64eb737079 255 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 98 118 - T 06-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CAK77_RS16335 3e786c870aee493883735e64eb737079 255 SUPERFAMILY SSF52096 7 254 1.34E-56 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS01375 6800d7a47fff6a0aea978d8a3aed3081 152 Gene3D G3DSA:3.40.140.10 4 149 8.6E-53 T 06-07-2017 CAK77_RS01375 6800d7a47fff6a0aea978d8a3aed3081 152 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 10 152 45.036 T 06-07-2017 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 CAK77_RS01375 6800d7a47fff6a0aea978d8a3aed3081 152 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 6 104 7.3E-24 T 06-07-2017 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 CAK77_RS01375 6800d7a47fff6a0aea978d8a3aed3081 152 SUPERFAMILY SSF53927 4 151 1.07E-45 T 06-07-2017 IPR016193 Cytidine deaminase-like GO:0003824 CAK77_RS01375 6800d7a47fff6a0aea978d8a3aed3081 152 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 55 93 - T 06-07-2017 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 CAK77_RS21230 e7f18e791e6808bf9355cebd751555db 309 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 66 289 1.6E-37 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAK77_RS21230 e7f18e791e6808bf9355cebd751555db 309 SMART SM00062 59 292 7.5E-23 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAK77_RS21230 e7f18e791e6808bf9355cebd751555db 309 Gene3D G3DSA:3.40.190.10 252 292 1.7E-24 T 06-07-2017 CAK77_RS21230 e7f18e791e6808bf9355cebd751555db 309 Gene3D G3DSA:3.40.190.10 56 138 1.7E-24 T 06-07-2017 CAK77_RS21230 e7f18e791e6808bf9355cebd751555db 309 SUPERFAMILY SSF53850 3 19 1.6E-41 T 06-07-2017 CAK77_RS21230 e7f18e791e6808bf9355cebd751555db 309 SUPERFAMILY SSF53850 49 292 1.6E-41 T 06-07-2017 CAK77_RS21230 e7f18e791e6808bf9355cebd751555db 309 Gene3D G3DSA:3.40.190.10 139 242 4.7E-22 T 06-07-2017 CAK77_RS11340 456a482899b121a16806864bf53efd07 336 SMART SM00044 111 297 1.1E-5 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CAK77_RS11340 456a482899b121a16806864bf53efd07 336 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 150 279 2.7E-9 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CAK77_RS11340 456a482899b121a16806864bf53efd07 336 Gene3D G3DSA:3.30.70.1230 149 325 6.4E-20 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CAK77_RS11340 456a482899b121a16806864bf53efd07 336 SUPERFAMILY SSF55073 145 325 1.24E-32 T 06-07-2017 IPR029787 Nucleotide cyclase CAK77_RS19090 1aa67579b96c3655400857448506f840 418 Pfam PF00067 Cytochrome P450 221 286 7.3E-6 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS19090 1aa67579b96c3655400857448506f840 418 Pfam PF00067 Cytochrome P450 292 389 3.1E-18 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS19090 1aa67579b96c3655400857448506f840 418 SUPERFAMILY SSF48264 25 418 4.32E-88 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS19090 1aa67579b96c3655400857448506f840 418 PRINTS PR00385 P450 superfamily signature 257 274 6.9E-6 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS19090 1aa67579b96c3655400857448506f840 418 PRINTS PR00385 P450 superfamily signature 367 378 6.9E-6 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS19090 1aa67579b96c3655400857448506f840 418 PRINTS PR00385 P450 superfamily signature 358 367 6.9E-6 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS19090 1aa67579b96c3655400857448506f840 418 PRINTS PR00359 B-class P450 signature 367 378 3.9E-46 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS19090 1aa67579b96c3655400857448506f840 418 PRINTS PR00359 B-class P450 signature 337 352 3.9E-46 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS19090 1aa67579b96c3655400857448506f840 418 PRINTS PR00359 B-class P450 signature 103 114 3.9E-46 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS19090 1aa67579b96c3655400857448506f840 418 PRINTS PR00359 B-class P450 signature 309 336 3.9E-46 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS19090 1aa67579b96c3655400857448506f840 418 PRINTS PR00359 B-class P450 signature 358 367 3.9E-46 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS19090 1aa67579b96c3655400857448506f840 418 PRINTS PR00359 B-class P450 signature 211 233 3.9E-46 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS19090 1aa67579b96c3655400857448506f840 418 PRINTS PR00359 B-class P450 signature 167 182 3.9E-46 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS19090 1aa67579b96c3655400857448506f840 418 PRINTS PR00359 B-class P450 signature 150 166 3.9E-46 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS19090 1aa67579b96c3655400857448506f840 418 PRINTS PR00359 B-class P450 signature 292 303 3.9E-46 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS19090 1aa67579b96c3655400857448506f840 418 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 360 369 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CAK77_RS19090 1aa67579b96c3655400857448506f840 418 Gene3D G3DSA:1.10.630.10 26 416 1.2E-108 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS16200 94b0df1ef33dce5d08fa3ee85e2d6683 286 Gene3D G3DSA:1.10.8.50 142 281 5.8E-45 T 06-07-2017 CAK77_RS16200 94b0df1ef33dce5d08fa3ee85e2d6683 286 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 140 227 1.2E-23 T 06-07-2017 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 CAK77_RS16200 94b0df1ef33dce5d08fa3ee85e2d6683 286 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 281 40.012 T 06-07-2017 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 CAK77_RS16200 94b0df1ef33dce5d08fa3ee85e2d6683 286 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 280 8.0E-90 T 06-07-2017 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 CAK77_RS16200 94b0df1ef33dce5d08fa3ee85e2d6683 286 Pfam PF06827 Zinc finger found in FPG and IleRS 253 280 2.2E-10 T 06-07-2017 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 CAK77_RS16200 94b0df1ef33dce5d08fa3ee85e2d6683 286 SUPERFAMILY SSF81624 2 145 3.27E-31 T 06-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CAK77_RS16200 94b0df1ef33dce5d08fa3ee85e2d6683 286 ProSitePatterns PS01242 Zinc finger FPG-type signature. 256 280 - T 06-07-2017 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 CAK77_RS16200 94b0df1ef33dce5d08fa3ee85e2d6683 286 SMART SM01232 140 232 1.0E-36 T 06-07-2017 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 CAK77_RS16200 94b0df1ef33dce5d08fa3ee85e2d6683 286 SUPERFAMILY SSF46946 140 229 4.42E-24 T 06-07-2017 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 CAK77_RS16200 94b0df1ef33dce5d08fa3ee85e2d6683 286 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 2 120 4.4E-32 T 06-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CAK77_RS16200 94b0df1ef33dce5d08fa3ee85e2d6683 286 SUPERFAMILY SSF57716 232 280 1.11E-15 T 06-07-2017 CAK77_RS16200 94b0df1ef33dce5d08fa3ee85e2d6683 286 SMART SM00898 2 121 4.8E-39 T 06-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CAK77_RS16200 94b0df1ef33dce5d08fa3ee85e2d6683 286 Gene3D G3DSA:3.20.190.10 2 124 2.7E-35 T 06-07-2017 CAK77_RS18825 8a86c7de3011155601b120f495285343 37 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 10 37 1.0E-8 T 06-07-2017 CAK77_RS18825 8a86c7de3011155601b120f495285343 37 SUPERFAMILY SSF57840 2 37 1.02E-15 T 06-07-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS18825 8a86c7de3011155601b120f495285343 37 Pfam PF00444 Ribosomal protein L36 2 37 1.3E-16 T 06-07-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS18825 8a86c7de3011155601b120f495285343 37 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 37 16.649 T 06-07-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS18825 8a86c7de3011155601b120f495285343 37 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 2 37 2.0E-20 T 06-07-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS18825 8a86c7de3011155601b120f495285343 37 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 36 - T 06-07-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS06670 c7fcf6140210e1685792f7aa06bab580 544 SUPERFAMILY SSF53720 8 525 3.8E-121 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAK77_RS06670 c7fcf6140210e1685792f7aa06bab580 544 Gene3D G3DSA:3.40.605.10 41 303 5.2E-59 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAK77_RS06670 c7fcf6140210e1685792f7aa06bab580 544 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 320 331 - T 06-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CAK77_RS06670 c7fcf6140210e1685792f7aa06bab580 544 TIGRFAM TIGR01236 D1pyr5carbox1: 1-pyrroline-5-carboxylate dehydrogenase 12 539 1.9E-252 T 06-07-2017 IPR005931 Delta-1-pyrroline-5-carboxylate dehydrogenase GO:0003842|GO:0006537|GO:0006561 KEGG: 00250+1.2.1.88|KEGG: 00330+1.2.1.88|MetaCyc: PWY-6853|Reactome: R-HSA-70688 CAK77_RS06670 c7fcf6140210e1685792f7aa06bab580 544 Gene3D G3DSA:3.40.309.10 304 498 4.7E-42 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAK77_RS06670 c7fcf6140210e1685792f7aa06bab580 544 Pfam PF00171 Aldehyde dehydrogenase family 53 518 2.2E-94 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAK77_RS15910 1d1dcdcb0f23539303c83c174c76934d 149 SUPERFAMILY SSF51261 12 139 8.89E-17 T 06-07-2017 IPR011055 Duplicated hybrid motif CAK77_RS15910 1d1dcdcb0f23539303c83c174c76934d 149 Gene3D G3DSA:2.70.70.10 9 139 6.8E-25 T 06-07-2017 CAK77_RS15910 1d1dcdcb0f23539303c83c174c76934d 149 Pfam PF01551 Peptidase family M23 37 123 2.2E-13 T 06-07-2017 IPR016047 Peptidase M23 CAK77_RS15045 3b89336c5be9b93d6a97ec1f7859aa93 298 Pfam PF05114 Protein of unknown function (DUF692) 18 280 8.6E-65 T 06-07-2017 IPR007801 Uncharacterised protein family UPF0276 CAK77_RS15045 3b89336c5be9b93d6a97ec1f7859aa93 298 Gene3D G3DSA:3.20.20.150 17 293 5.9E-71 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain CAK77_RS15045 3b89336c5be9b93d6a97ec1f7859aa93 298 SUPERFAMILY SSF51658 56 238 1.24E-10 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain CAK77_RS05645 1962bb81c5609d74437488d54bd40f42 549 ProSitePatterns PS00455 Putative AMP-binding domain signature. 157 168 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK77_RS05645 1962bb81c5609d74437488d54bd40f42 549 Gene3D G3DSA:2.30.38.10 364 435 1.5E-15 T 06-07-2017 CAK77_RS05645 1962bb81c5609d74437488d54bd40f42 549 Pfam PF00501 AMP-binding enzyme 26 443 6.0E-66 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK77_RS05645 1962bb81c5609d74437488d54bd40f42 549 Gene3D G3DSA:3.40.50.980 166 331 3.3E-33 T 06-07-2017 CAK77_RS05645 1962bb81c5609d74437488d54bd40f42 549 Gene3D G3DSA:3.40.50.980 28 165 6.0E-21 T 06-07-2017 CAK77_RS05645 1962bb81c5609d74437488d54bd40f42 549 SUPERFAMILY SSF56801 23 542 1.06E-95 T 06-07-2017 CAK77_RS05645 1962bb81c5609d74437488d54bd40f42 549 Gene3D G3DSA:3.30.300.30 436 542 1.6E-17 T 06-07-2017 CAK77_RS05475 9f790d49f2cdeb08d509c4555300f16f 339 Gene3D G3DSA:1.20.1070.10 221 261 2.8E-4 T 06-07-2017 CAK77_RS23800 9beedc6eed8414b74ac66ae3517bcf33 302 SUPERFAMILY SSF51989 14 301 8.11E-95 T 06-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CAK77_RS23800 9beedc6eed8414b74ac66ae3517bcf33 302 PRINTS PR00733 Glycosyl hydrolase family 6 signature 221 234 1.4E-39 T 06-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CAK77_RS23800 9beedc6eed8414b74ac66ae3517bcf33 302 PRINTS PR00733 Glycosyl hydrolase family 6 signature 191 201 1.4E-39 T 06-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CAK77_RS23800 9beedc6eed8414b74ac66ae3517bcf33 302 PRINTS PR00733 Glycosyl hydrolase family 6 signature 262 276 1.4E-39 T 06-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CAK77_RS23800 9beedc6eed8414b74ac66ae3517bcf33 302 PRINTS PR00733 Glycosyl hydrolase family 6 signature 78 91 1.4E-39 T 06-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CAK77_RS23800 9beedc6eed8414b74ac66ae3517bcf33 302 PRINTS PR00733 Glycosyl hydrolase family 6 signature 238 258 1.4E-39 T 06-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CAK77_RS23800 9beedc6eed8414b74ac66ae3517bcf33 302 PRINTS PR00733 Glycosyl hydrolase family 6 signature 106 121 1.4E-39 T 06-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CAK77_RS23800 9beedc6eed8414b74ac66ae3517bcf33 302 PRINTS PR00733 Glycosyl hydrolase family 6 signature 161 174 1.4E-39 T 06-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CAK77_RS23800 9beedc6eed8414b74ac66ae3517bcf33 302 PRINTS PR00733 Glycosyl hydrolase family 6 signature 38 57 1.4E-39 T 06-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CAK77_RS23800 9beedc6eed8414b74ac66ae3517bcf33 302 ProSitePatterns PS00656 Glycosyl hydrolases family 6 signature 2. 123 132 - T 06-07-2017 IPR001524 Glycoside hydrolase, family 6, conserved site GO:0004553|GO:0005975 CAK77_RS23800 9beedc6eed8414b74ac66ae3517bcf33 302 PIRSF PIRSF001100 11 302 3.2E-95 T 06-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CAK77_RS23800 9beedc6eed8414b74ac66ae3517bcf33 302 Pfam PF01341 Glycosyl hydrolases family 6 37 285 1.3E-69 T 06-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CAK77_RS23800 9beedc6eed8414b74ac66ae3517bcf33 302 Gene3D G3DSA:3.20.20.40 22 300 8.1E-90 T 06-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CAK77_RS01960 e70f64bf46273dbf74de65a81b493bcb 324 SUPERFAMILY SSF52540 15 300 1.6E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS01960 e70f64bf46273dbf74de65a81b493bcb 324 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 48 178 7.5E-64 T 06-07-2017 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 CAK77_RS01960 e70f64bf46273dbf74de65a81b493bcb 324 Gene3D G3DSA:3.40.50.300 29 194 5.9E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS01960 e70f64bf46273dbf74de65a81b493bcb 324 SMART SM00382 45 186 0.0029 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS01960 e70f64bf46273dbf74de65a81b493bcb 324 PIRSF PIRSF002849 2 324 3.2E-134 T 06-07-2017 IPR016366 ATPase chaperone, AAA-type, MoxR, predicted CAK77_RS01960 e70f64bf46273dbf74de65a81b493bcb 324 Gene3D G3DSA:1.10.8.300 212 319 8.0E-37 T 06-07-2017 CAK77_RS06260 5175cf5fd58bdcb80e5845765f935565 191 SUPERFAMILY SSF88659 123 187 1.35E-10 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS06260 5175cf5fd58bdcb80e5845765f935565 191 Gene3D G3DSA:1.10.10.10 125 188 9.8E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS06260 5175cf5fd58bdcb80e5845765f935565 191 Pfam PF04542 Sigma-70 region 2 35 102 3.0E-16 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS06260 5175cf5fd58bdcb80e5845765f935565 191 Gene3D G3DSA:1.10.1740.10 13 121 3.4E-30 T 06-07-2017 CAK77_RS06260 5175cf5fd58bdcb80e5845765f935565 191 SUPERFAMILY SSF88946 12 113 1.22E-27 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS06260 5175cf5fd58bdcb80e5845765f935565 191 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 30 185 1.4E-25 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS06260 5175cf5fd58bdcb80e5845765f935565 191 Pfam PF08281 Sigma-70, region 4 131 182 1.0E-8 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS17455 6c3c537b6a29d17d45bbc3392a7848a0 263 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 85 98 - T 06-07-2017 IPR020583 Inositol monophosphatase, metal-binding site CAK77_RS17455 6c3c537b6a29d17d45bbc3392a7848a0 263 PRINTS PR00377 Inositol monophosphatase superfamily signature 43 63 6.3E-17 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAK77_RS17455 6c3c537b6a29d17d45bbc3392a7848a0 263 PRINTS PR00377 Inositol monophosphatase superfamily signature 65 81 6.3E-17 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAK77_RS17455 6c3c537b6a29d17d45bbc3392a7848a0 263 PRINTS PR00377 Inositol monophosphatase superfamily signature 214 238 6.3E-17 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAK77_RS17455 6c3c537b6a29d17d45bbc3392a7848a0 263 PRINTS PR00377 Inositol monophosphatase superfamily signature 85 101 6.3E-17 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAK77_RS17455 6c3c537b6a29d17d45bbc3392a7848a0 263 TIGRFAM TIGR02067 his_9_HisN: histidinol-phosphatase 11 262 7.1E-88 T 06-07-2017 IPR011809 Histidinol-phosphate phosphatase, putative, inositol monophosphatase GO:0004401 KEGG: 00340+3.1.3.15 CAK77_RS17455 6c3c537b6a29d17d45bbc3392a7848a0 263 SUPERFAMILY SSF56655 7 262 3.66E-71 T 06-07-2017 CAK77_RS17455 6c3c537b6a29d17d45bbc3392a7848a0 263 Gene3D G3DSA:3.40.190.80 159 262 8.5E-22 T 06-07-2017 CAK77_RS17455 6c3c537b6a29d17d45bbc3392a7848a0 263 Gene3D G3DSA:3.30.540.10 6 158 5.0E-44 T 06-07-2017 CAK77_RS17455 6c3c537b6a29d17d45bbc3392a7848a0 263 Pfam PF00459 Inositol monophosphatase family 8 261 2.3E-45 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAK77_RS19130 d3b40b2e31c12c54ae2e7601d81e2551 392 TIGRFAM TIGR03966 actino_HemFlav: heme/flavin dehydrogenase, mycofactocin system 4 387 7.5E-218 T 06-07-2017 IPR023989 Heme/flavin dehydrogenase, Rv0694 CAK77_RS19130 d3b40b2e31c12c54ae2e7601d81e2551 392 Pfam PF01070 FMN-dependent dehydrogenase 17 378 1.8E-107 T 06-07-2017 IPR000262 FMN-dependent dehydrogenase GO:0016491 CAK77_RS19130 d3b40b2e31c12c54ae2e7601d81e2551 392 SUPERFAMILY SSF51395 227 380 9.16E-79 T 06-07-2017 CAK77_RS19130 d3b40b2e31c12c54ae2e7601d81e2551 392 SUPERFAMILY SSF51395 14 197 9.16E-79 T 06-07-2017 CAK77_RS19130 d3b40b2e31c12c54ae2e7601d81e2551 392 PIRSF PIRSF000138 2 383 1.8E-102 T 06-07-2017 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 CAK77_RS19130 d3b40b2e31c12c54ae2e7601d81e2551 392 Gene3D G3DSA:3.20.20.70 13 380 7.8E-112 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK77_RS18160 e17bfd88842231cee6a9858eafee4b89 455 SUPERFAMILY SSF53383 49 452 2.81E-82 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK77_RS18160 e17bfd88842231cee6a9858eafee4b89 455 PIRSF PIRSF000521 9 454 7.6E-151 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAK77_RS18160 e17bfd88842231cee6a9858eafee4b89 455 TIGRFAM TIGR03251 LAT_fam: L-lysine 6-transaminase 27 452 4.1E-224 T 06-07-2017 IPR017657 L-lysine 6-transaminase GO:0017000|GO:0030170|GO:0045484 MetaCyc: PWY-5298 CAK77_RS18160 e17bfd88842231cee6a9858eafee4b89 455 Pfam PF00202 Aminotransferase class-III 46 452 1.2E-74 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAK77_RS18160 e17bfd88842231cee6a9858eafee4b89 455 Gene3D G3DSA:3.40.640.10 99 357 2.4E-63 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK77_RS18160 e17bfd88842231cee6a9858eafee4b89 455 Gene3D G3DSA:3.90.1150.10 360 453 9.4E-28 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK77_RS18160 e17bfd88842231cee6a9858eafee4b89 455 Gene3D G3DSA:3.90.1150.10 49 82 9.4E-28 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK77_RS18160 e17bfd88842231cee6a9858eafee4b89 455 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 275 312 - T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAK77_RS09410 9705b507f558962f1cedab1407486095 430 SUPERFAMILY SSF51905 277 393 9.93E-9 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS09410 9705b507f558962f1cedab1407486095 430 SUPERFAMILY SSF51905 193 248 9.93E-9 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS09410 9705b507f558962f1cedab1407486095 430 Gene3D G3DSA:3.50.50.60 204 240 4.3E-8 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS09410 9705b507f558962f1cedab1407486095 430 Gene3D G3DSA:3.50.50.60 285 340 4.3E-8 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS09410 9705b507f558962f1cedab1407486095 430 SUPERFAMILY SSF51905 8 241 4.97E-24 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS09410 9705b507f558962f1cedab1407486095 430 Gene3D G3DSA:3.50.50.60 8 203 4.7E-15 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS09410 9705b507f558962f1cedab1407486095 430 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 8 342 8.9E-107 T 06-07-2017 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase CAK77_RS10810 ea4e078b449a4d1d34527b9f3bc02349 353 Gene3D G3DSA:3.40.190.10 80 154 2.7E-7 T 06-07-2017 CAK77_RS10810 ea4e078b449a4d1d34527b9f3bc02349 353 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 81 243 2.8E-14 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAK77_RS10810 ea4e078b449a4d1d34527b9f3bc02349 353 TIGRFAM TIGR01728 SsuA_fam: ABC transporter, substrate-binding protein, aliphatic sulfonates family 60 342 8.2E-59 T 06-07-2017 IPR010067 Aliphatic sulfonates-binding protein GO:0006790|GO:0006810|GO:0016020 CAK77_RS10810 ea4e078b449a4d1d34527b9f3bc02349 353 SUPERFAMILY SSF53850 58 278 4.56E-45 T 06-07-2017 CAK77_RS10810 ea4e078b449a4d1d34527b9f3bc02349 353 Gene3D G3DSA:3.40.190.10 155 250 2.1E-25 T 06-07-2017 CAK77_RS10810 ea4e078b449a4d1d34527b9f3bc02349 353 SMART SM00062 59 285 1.4E-7 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAK77_RS12450 67c448e1f29120e3be5dd4ada6fe1989 178 Gene3D G3DSA:3.40.630.30 21 148 1.4E-15 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS12450 67c448e1f29120e3be5dd4ada6fe1989 178 Pfam PF00583 Acetyltransferase (GNAT) family 79 150 2.0E-6 T 06-07-2017 IPR000182 GNAT domain GO:0008080 CAK77_RS12450 67c448e1f29120e3be5dd4ada6fe1989 178 SUPERFAMILY SSF55729 21 150 2.7E-16 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS14315 e3c33622013badf6059cfff1dc867cf2 315 SUPERFAMILY SSF52402 180 294 2.85E-6 T 06-07-2017 CAK77_RS14315 e3c33622013badf6059cfff1dc867cf2 315 Pfam PF00582 Universal stress protein family 38 168 3.9E-14 T 06-07-2017 IPR006016 UspA GO:0006950 CAK77_RS14315 e3c33622013badf6059cfff1dc867cf2 315 SUPERFAMILY SSF52402 38 170 2.85E-17 T 06-07-2017 CAK77_RS14315 e3c33622013badf6059cfff1dc867cf2 315 Gene3D G3DSA:3.40.50.620 38 162 1.2E-15 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS14315 e3c33622013badf6059cfff1dc867cf2 315 Gene3D G3DSA:3.40.50.620 163 294 3.6E-12 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS14380 ab31fd5b37625ea4db24cc6a3c78e4d5 291 Gene3D G3DSA:3.40.50.620 158 289 1.9E-29 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS14380 ab31fd5b37625ea4db24cc6a3c78e4d5 291 Pfam PF00582 Universal stress protein family 159 289 3.8E-21 T 06-07-2017 IPR006016 UspA GO:0006950 CAK77_RS14380 ab31fd5b37625ea4db24cc6a3c78e4d5 291 Pfam PF00582 Universal stress protein family 10 148 1.6E-23 T 06-07-2017 IPR006016 UspA GO:0006950 CAK77_RS14380 ab31fd5b37625ea4db24cc6a3c78e4d5 291 SUPERFAMILY SSF52402 159 289 3.85E-28 T 06-07-2017 CAK77_RS14380 ab31fd5b37625ea4db24cc6a3c78e4d5 291 SUPERFAMILY SSF52402 10 150 2.51E-29 T 06-07-2017 CAK77_RS14380 ab31fd5b37625ea4db24cc6a3c78e4d5 291 PRINTS PR01438 Universal stress protein signature 267 289 6.4E-13 T 06-07-2017 IPR006015 Universal stress protein A CAK77_RS14380 ab31fd5b37625ea4db24cc6a3c78e4d5 291 PRINTS PR01438 Universal stress protein signature 249 261 6.4E-13 T 06-07-2017 IPR006015 Universal stress protein A CAK77_RS14380 ab31fd5b37625ea4db24cc6a3c78e4d5 291 PRINTS PR01438 Universal stress protein signature 156 174 6.4E-13 T 06-07-2017 IPR006015 Universal stress protein A CAK77_RS14380 ab31fd5b37625ea4db24cc6a3c78e4d5 291 Gene3D G3DSA:3.40.50.620 8 149 1.3E-31 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS06460 308f5ea84b2894be5023901694956f43 270 SUPERFAMILY SSF54427 9 128 4.15E-14 T 06-07-2017 IPR032710 NTF2-like domain CAK77_RS06460 308f5ea84b2894be5023901694956f43 270 Pfam PF02136 Nuclear transport factor 2 (NTF2) domain 11 88 5.5E-5 T 06-07-2017 IPR002075 Nuclear transport factor 2 GO:0005622|GO:0006810 CAK77_RS06460 308f5ea84b2894be5023901694956f43 270 Gene3D G3DSA:3.10.450.50 8 133 6.4E-26 T 06-07-2017 IPR032710 NTF2-like domain CAK77_RS04775 1d0a5deb71007ac6a07457632a3d6fad 132 Pfam PF03061 Thioesterase superfamily 41 119 1.5E-14 T 06-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 CAK77_RS04775 1d0a5deb71007ac6a07457632a3d6fad 132 SUPERFAMILY SSF54637 4 126 1.21E-29 T 06-07-2017 IPR029069 HotDog domain CAK77_RS04775 1d0a5deb71007ac6a07457632a3d6fad 132 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 13 126 6.8E-23 T 06-07-2017 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-75105 CAK77_RS04775 1d0a5deb71007ac6a07457632a3d6fad 132 Gene3D G3DSA:3.10.129.10 4 130 1.6E-39 T 06-07-2017 IPR029069 HotDog domain CAK77_RS02610 73f204d94e81bde332857225b809b4e6 186 Gene3D G3DSA:1.10.10.60 7 59 3.0E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS02610 73f204d94e81bde332857225b809b4e6 186 Gene3D G3DSA:1.10.357.10 60 167 8.1E-21 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS02610 73f204d94e81bde332857225b809b4e6 186 Pfam PF13305 WHG domain 79 161 4.3E-18 T 06-07-2017 IPR025996 WHG domain CAK77_RS02610 73f204d94e81bde332857225b809b4e6 186 SUPERFAMILY SSF48498 72 174 2.13E-20 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS02610 73f204d94e81bde332857225b809b4e6 186 SUPERFAMILY SSF46689 3 74 2.15E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS02610 73f204d94e81bde332857225b809b4e6 186 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 58 1.3E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS18740 75128a31c463cb928492f3748aef3210 511 PIRSF PIRSF017804 9 510 5.5E-75 T 06-07-2017 IPR006707 Type VII secretion system membrane protein EccD CAK77_RS18740 75128a31c463cb928492f3748aef3210 511 TIGRFAM TIGR03920 T7SS_EccD: type VII secretion integral membrane protein EccD 20 507 8.0E-92 T 06-07-2017 IPR006707 Type VII secretion system membrane protein EccD CAK77_RS18740 75128a31c463cb928492f3748aef3210 511 Pfam PF08817 WXG100 protein secretion system (Wss), protein YukD 17 99 5.4E-21 T 06-07-2017 IPR024962 YukD-like CAK77_RS19350 a509b3c208f54b5dfe98f077f9fee379 176 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 66 150 0.001 T 06-07-2017 CAK77_RS19350 a509b3c208f54b5dfe98f077f9fee379 176 SUPERFAMILY SSF160369 1 169 1.18E-48 T 06-07-2017 CAK77_RS19350 a509b3c208f54b5dfe98f077f9fee379 176 ProSitePatterns PS01109 Ribosomal protein L10 signature. 6 40 - T 06-07-2017 IPR002363 Ribosomal protein L10, eubacterial, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS19350 a509b3c208f54b5dfe98f077f9fee379 176 Pfam PF00466 Ribosomal protein L10 1 98 1.7E-25 T 06-07-2017 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 CAK77_RS19350 a509b3c208f54b5dfe98f077f9fee379 176 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 1 158 24.588 T 06-07-2017 IPR022973 Ribosomal protein L10 CAK77_RS04520 841a4aa6be0ed43fbac09a3fc106bfa9 409 SUPERFAMILY SSF51735 1 150 2.25E-23 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS04520 841a4aa6be0ed43fbac09a3fc106bfa9 409 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 4 129 6.5E-15 T 06-07-2017 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 CAK77_RS04520 841a4aa6be0ed43fbac09a3fc106bfa9 409 Gene3D G3DSA:3.40.50.720 1 157 9.3E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS05295 1054540f376eb3d6c6d8cc22382772ef 96 SUPERFAMILY SSF48600 17 80 9.46E-15 T 06-07-2017 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CAK77_RS05295 1054540f376eb3d6c6d8cc22382772ef 96 Gene3D G3DSA:1.20.59.10 15 77 4.9E-16 T 06-07-2017 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CAK77_RS05295 1054540f376eb3d6c6d8cc22382772ef 96 TIGRFAM TIGR01808 CM_M_hiGC-arch: chorismate mutase 20 92 2.9E-35 T 06-07-2017 IPR010958 Chorismate mutase, high GC Gram-positive bacteria/archaeal CAK77_RS05295 1054540f376eb3d6c6d8cc22382772ef 96 SMART SM00830 24 91 6.0E-8 T 06-07-2017 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CAK77_RS05295 1054540f376eb3d6c6d8cc22382772ef 96 Pfam PF01817 Chorismate mutase type II 24 74 2.7E-11 T 06-07-2017 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CAK77_RS05410 7feb5aa17358b4c7cb223f625a2e931b 520 SMART SM00387 362 482 2.6E-32 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS05410 7feb5aa17358b4c7cb223f625a2e931b 520 SMART SM00388 250 322 5.0E-12 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK77_RS05410 7feb5aa17358b4c7cb223f625a2e931b 520 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 362 479 5.3E-20 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS05410 7feb5aa17358b4c7cb223f625a2e931b 520 SUPERFAMILY SSF158472 200 246 2.22E-6 T 06-07-2017 CAK77_RS05410 7feb5aa17358b4c7cb223f625a2e931b 520 PRINTS PR00344 Bacterial sensor protein C-terminal signature 418 428 8.5E-11 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK77_RS05410 7feb5aa17358b4c7cb223f625a2e931b 520 PRINTS PR00344 Bacterial sensor protein C-terminal signature 400 414 8.5E-11 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK77_RS05410 7feb5aa17358b4c7cb223f625a2e931b 520 PRINTS PR00344 Bacterial sensor protein C-terminal signature 433 451 8.5E-11 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK77_RS05410 7feb5aa17358b4c7cb223f625a2e931b 520 SUPERFAMILY SSF47384 233 320 1.96E-13 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK77_RS05410 7feb5aa17358b4c7cb223f625a2e931b 520 SUPERFAMILY SSF55874 312 479 1.15E-33 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS05410 7feb5aa17358b4c7cb223f625a2e931b 520 Gene3D G3DSA:3.30.565.10 325 480 2.7E-35 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS05410 7feb5aa17358b4c7cb223f625a2e931b 520 Pfam PF00672 HAMP domain 177 245 3.1E-13 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAK77_RS05410 7feb5aa17358b4c7cb223f625a2e931b 520 Gene3D G3DSA:1.10.287.130 240 318 4.5E-14 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK77_RS05410 7feb5aa17358b4c7cb223f625a2e931b 520 Pfam PF00512 His Kinase A (phospho-acceptor) domain 251 321 1.1E-12 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK77_RS05410 7feb5aa17358b4c7cb223f625a2e931b 520 SMART SM00304 197 249 1.1E-9 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAK77_RS13150 e7fdb3ae0bdf95c927109b0e6f9374dc 242 Pfam PF10821 Protein of unknown function (DUF2567) 52 217 7.3E-68 T 06-07-2017 IPR021213 Protein of unknown function DUF2567 CAK77_RS18870 30e921d558d47bbd9ffa481eeeee5393 264 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 14 262 2.4E-77 T 06-07-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 CAK77_RS18870 30e921d558d47bbd9ffa481eeeee5393 264 PRINTS PR00599 Methionine aminopeptidase-1 signature 174 186 7.9E-20 T 06-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase CAK77_RS18870 30e921d558d47bbd9ffa481eeeee5393 264 PRINTS PR00599 Methionine aminopeptidase-1 signature 75 88 7.9E-20 T 06-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase CAK77_RS18870 30e921d558d47bbd9ffa481eeeee5393 264 PRINTS PR00599 Methionine aminopeptidase-1 signature 98 114 7.9E-20 T 06-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase CAK77_RS18870 30e921d558d47bbd9ffa481eeeee5393 264 PRINTS PR00599 Methionine aminopeptidase-1 signature 205 217 7.9E-20 T 06-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase CAK77_RS18870 30e921d558d47bbd9ffa481eeeee5393 264 Gene3D G3DSA:3.90.230.10 13 263 2.4E-77 T 06-07-2017 IPR000994 Peptidase M24, structural domain CAK77_RS18870 30e921d558d47bbd9ffa481eeeee5393 264 Hamap MF_01974 Methionine aminopeptidase [map]. 10 263 37.071 T 06-07-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 CAK77_RS18870 30e921d558d47bbd9ffa481eeeee5393 264 SUPERFAMILY SSF55920 13 263 6.02E-73 T 06-07-2017 IPR000994 Peptidase M24, structural domain CAK77_RS18870 30e921d558d47bbd9ffa481eeeee5393 264 Pfam PF00557 Metallopeptidase family M24 20 254 4.5E-41 T 06-07-2017 IPR000994 Peptidase M24, structural domain CAK77_RS20690 7d3a045ff2dae21658e45b188baa8293 465 SUPERFAMILY SSF51905 3 334 6.74E-63 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS20690 7d3a045ff2dae21658e45b188baa8293 465 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 346 454 2.5E-35 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CAK77_RS20690 7d3a045ff2dae21658e45b188baa8293 465 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 39 49 - T 06-07-2017 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 CAK77_RS20690 7d3a045ff2dae21658e45b188baa8293 465 PIRSF PIRSF000350 1 459 1.3E-88 T 06-07-2017 CAK77_RS20690 7d3a045ff2dae21658e45b188baa8293 465 SUPERFAMILY SSF55424 342 464 1.7E-38 T 06-07-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CAK77_RS20690 7d3a045ff2dae21658e45b188baa8293 465 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 325 3.5E-67 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS20690 7d3a045ff2dae21658e45b188baa8293 465 Gene3D G3DSA:3.50.50.60 143 331 1.1E-55 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS20690 7d3a045ff2dae21658e45b188baa8293 465 Gene3D G3DSA:3.30.390.30 332 463 1.3E-44 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CAK77_RS20690 7d3a045ff2dae21658e45b188baa8293 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 262 276 1.5E-66 T 06-07-2017 CAK77_RS20690 7d3a045ff2dae21658e45b188baa8293 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 407 422 1.5E-66 T 06-07-2017 CAK77_RS20690 7d3a045ff2dae21658e45b188baa8293 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 429 449 1.5E-66 T 06-07-2017 CAK77_RS20690 7d3a045ff2dae21658e45b188baa8293 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 1.5E-66 T 06-07-2017 CAK77_RS20690 7d3a045ff2dae21658e45b188baa8293 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 174 199 1.5E-66 T 06-07-2017 CAK77_RS20690 7d3a045ff2dae21658e45b188baa8293 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 305 312 1.5E-66 T 06-07-2017 CAK77_RS20690 7d3a045ff2dae21658e45b188baa8293 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 139 148 1.5E-66 T 06-07-2017 CAK77_RS20690 7d3a045ff2dae21658e45b188baa8293 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 1.5E-66 T 06-07-2017 CAK77_RS20690 7d3a045ff2dae21658e45b188baa8293 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 342 363 1.5E-66 T 06-07-2017 CAK77_RS20690 7d3a045ff2dae21658e45b188baa8293 465 Gene3D G3DSA:3.50.50.60 3 142 3.9E-38 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS20690 7d3a045ff2dae21658e45b188baa8293 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 261 277 1.5E-38 T 06-07-2017 CAK77_RS20690 7d3a045ff2dae21658e45b188baa8293 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 1.5E-38 T 06-07-2017 CAK77_RS20690 7d3a045ff2dae21658e45b188baa8293 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 290 312 1.5E-38 T 06-07-2017 CAK77_RS20690 7d3a045ff2dae21658e45b188baa8293 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 136 154 1.5E-38 T 06-07-2017 CAK77_RS20690 7d3a045ff2dae21658e45b188baa8293 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 174 192 1.5E-38 T 06-07-2017 CAK77_RS20690 7d3a045ff2dae21658e45b188baa8293 465 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 4 464 6.4E-169 T 06-07-2017 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 CAK77_RS20490 8a12d8f24dee39df36317529bf04e37d 517 Pfam PF13520 Amino acid permease 43 484 8.4E-36 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CAK77_RS20490 8a12d8f24dee39df36317529bf04e37d 517 TIGRFAM TIGR03428 ureacarb_perm: permease, urea carboxylase system 24 502 3.6E-248 T 06-07-2017 IPR017794 Urea carboxylase-associated, permease CAK77_RS03260 0f18db043f6e3e13fe7b60ebea3a8ccf 638 SUPERFAMILY SSF52540 386 623 9.79E-27 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS03260 0f18db043f6e3e13fe7b60ebea3a8ccf 638 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 387 549 4.3E-11 T 06-07-2017 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain CAK77_RS03260 0f18db043f6e3e13fe7b60ebea3a8ccf 638 Gene3D G3DSA:3.40.50.300 386 620 4.8E-28 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS15560 c44453959429895200d06290932f41a6 158 ProSitePatterns PS01319 Ribosome-binding factor A signature. 79 100 - T 06-07-2017 IPR020053 Ribosome-binding factor A, conserved site GO:0006364 CAK77_RS15560 c44453959429895200d06290932f41a6 158 SUPERFAMILY SSF89919 3 115 2.62E-27 T 06-07-2017 IPR023799 Ribosome-binding factor A domain CAK77_RS15560 c44453959429895200d06290932f41a6 158 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 2 120 18.897 T 06-07-2017 IPR000238 Ribosome-binding factor A GO:0006364 CAK77_RS15560 c44453959429895200d06290932f41a6 158 Gene3D G3DSA:3.30.300.20 3 120 4.4E-33 T 06-07-2017 IPR015946 K homology domain-like, alpha/beta CAK77_RS15560 c44453959429895200d06290932f41a6 158 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 9 100 5.0E-30 T 06-07-2017 IPR000238 Ribosome-binding factor A GO:0006364 CAK77_RS15560 c44453959429895200d06290932f41a6 158 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 5 114 1.3E-19 T 06-07-2017 IPR000238 Ribosome-binding factor A GO:0006364 CAK77_RS15560 c44453959429895200d06290932f41a6 158 Pfam PF02033 Ribosome-binding factor A 6 113 1.7E-24 T 06-07-2017 IPR000238 Ribosome-binding factor A GO:0006364 CAK77_RS16195 e2e118d74708fb52da9e0f61629f16b2 34 Pfam PF09604 F subunit of K+-transporting ATPase (Potass_KdpF) 11 34 1.1E-8 T 06-07-2017 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 CAK77_RS16195 e2e118d74708fb52da9e0f61629f16b2 34 TIGRFAM TIGR02115 potass_kdpF: K+-transporting ATPase, F subunit 11 34 6.0E-10 T 06-07-2017 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 CAK77_RS17015 0d3da9f20218eb3d0400c46a1f09e5fc 156 TIGRFAM TIGR00333 nrdI: nrdI protein 5 142 5.9E-45 T 06-07-2017 IPR004465 Ribonucleotide reductase Class Ib, NrdI CAK77_RS17015 0d3da9f20218eb3d0400c46a1f09e5fc 156 PIRSF PIRSF005087 1 149 3.6E-51 T 06-07-2017 IPR004465 Ribonucleotide reductase Class Ib, NrdI CAK77_RS17015 0d3da9f20218eb3d0400c46a1f09e5fc 156 SUPERFAMILY SSF52218 3 144 1.26E-24 T 06-07-2017 IPR029039 Flavoprotein-like domain CAK77_RS17015 0d3da9f20218eb3d0400c46a1f09e5fc 156 Hamap MF_00128 Protein NrdI [nrdI]. 3 145 33.442 T 06-07-2017 IPR020852 Ribonucleotide reductase, class Ib, NrdI, bacterial CAK77_RS17015 0d3da9f20218eb3d0400c46a1f09e5fc 156 Gene3D G3DSA:3.40.50.360 4 144 1.2E-51 T 06-07-2017 IPR029039 Flavoprotein-like domain CAK77_RS17015 0d3da9f20218eb3d0400c46a1f09e5fc 156 Pfam PF07972 NrdI Flavodoxin like 5 134 1.3E-44 T 06-07-2017 IPR004465 Ribonucleotide reductase Class Ib, NrdI CAK77_RS22695 ce1aaf8bae092fd20f6a2bd3511de17d 383 Gene3D G3DSA:3.90.180.10 8 198 7.3E-58 T 06-07-2017 IPR011032 GroES-like CAK77_RS22695 ce1aaf8bae092fd20f6a2bd3511de17d 383 Gene3D G3DSA:3.40.50.720 199 320 3.4E-24 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS22695 ce1aaf8bae092fd20f6a2bd3511de17d 383 SMART SM00829 19 376 2.2E-5 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAK77_RS22695 ce1aaf8bae092fd20f6a2bd3511de17d 383 TIGRFAM TIGR03989 Rxyl_3153: NDMA-dependent alcohol dehydrogenase, Rxyl_3153 family 11 378 1.5E-175 T 06-07-2017 IPR023921 Alcohol dehydrogenase, zinc-type, actinomycetes KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396 CAK77_RS22695 ce1aaf8bae092fd20f6a2bd3511de17d 383 SUPERFAMILY SSF50129 9 201 1.29E-57 T 06-07-2017 IPR011032 GroES-like CAK77_RS22695 ce1aaf8bae092fd20f6a2bd3511de17d 383 Pfam PF00107 Zinc-binding dehydrogenase 205 327 1.7E-17 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAK77_RS22695 ce1aaf8bae092fd20f6a2bd3511de17d 383 SUPERFAMILY SSF51735 167 342 4.47E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS22695 ce1aaf8bae092fd20f6a2bd3511de17d 383 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 37 163 1.5E-26 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAK77_RS22695 ce1aaf8bae092fd20f6a2bd3511de17d 383 SUPERFAMILY SSF50129 330 378 3.01E-10 T 06-07-2017 IPR011032 GroES-like CAK77_RS22695 ce1aaf8bae092fd20f6a2bd3511de17d 383 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 69 83 - T 06-07-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CAK77_RS12245 e11f6931606b26aff847c1da04beb628 78 Pfam PF05532 CsbD-like 12 61 1.9E-10 T 06-07-2017 IPR008462 CsbD-like CAK77_RS12245 e11f6931606b26aff847c1da04beb628 78 Gene3D G3DSA:1.10.1470.10 10 68 1.1E-7 T 06-07-2017 IPR008462 CsbD-like CAK77_RS12245 e11f6931606b26aff847c1da04beb628 78 SUPERFAMILY SSF69047 9 64 1.31E-7 T 06-07-2017 IPR008462 CsbD-like CAK77_RS21445 4289d2eb2cb694bb17a977951979e4cc 178 Gene3D G3DSA:3.30.530.20 17 161 6.1E-31 T 06-07-2017 IPR023393 START-like domain CAK77_RS21445 4289d2eb2cb694bb17a977951979e4cc 178 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 30 156 1.1E-16 T 06-07-2017 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CAK77_RS21445 4289d2eb2cb694bb17a977951979e4cc 178 SUPERFAMILY SSF55961 21 164 1.79E-31 T 06-07-2017 CAK77_RS12725 f4741300707a0ae1d4ce336ef29a0252 116 SUPERFAMILY SSF51182 13 111 4.69E-18 T 06-07-2017 IPR011051 RmlC-like cupin domain CAK77_RS12725 f4741300707a0ae1d4ce336ef29a0252 116 ProDom PD080544 SYNTHASE 4.2.1.- LYASE L-ECTOINE DEHYDRATASE N-ACETYLDIAMINOBUTYRATE ECTOINE ENZYME SYNTHASE:ECTOINE ECTC 1 111 4.0E-29 T 06-07-2017 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108|KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAK77_RS12725 f4741300707a0ae1d4ce336ef29a0252 116 Gene3D G3DSA:2.60.120.10 4 109 2.1E-13 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK77_RS12725 f4741300707a0ae1d4ce336ef29a0252 116 Pfam PF06339 Ectoine synthase 1 111 3.4E-42 T 06-07-2017 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108|KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAK77_RS15080 24d6df8d2966ccaf0f99c018d059cce7 228 SUPERFAMILY SSF46785 2 62 5.71E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS15080 24d6df8d2966ccaf0f99c018d059cce7 228 SUPERFAMILY SSF50037 130 228 5.95E-28 T 06-07-2017 IPR008988 Transcriptional repressor, C-terminal CAK77_RS15080 24d6df8d2966ccaf0f99c018d059cce7 228 Gene3D G3DSA:1.10.10.10 3 72 8.0E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS15080 24d6df8d2966ccaf0f99c018d059cce7 228 Pfam PF04023 FeoA domain 151 226 4.5E-10 T 06-07-2017 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CAK77_RS15080 24d6df8d2966ccaf0f99c018d059cce7 228 Gene3D G3DSA:1.10.60.10 75 133 4.0E-30 T 06-07-2017 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 CAK77_RS15080 24d6df8d2966ccaf0f99c018d059cce7 228 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 65 133 3.4E-28 T 06-07-2017 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 CAK77_RS15080 24d6df8d2966ccaf0f99c018d059cce7 228 SMART SM00899 151 227 6.9E-13 T 06-07-2017 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CAK77_RS15080 24d6df8d2966ccaf0f99c018d059cce7 228 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 3 62 1.9E-21 T 06-07-2017 IPR022687 DTXR-type HTH domain GO:0003677 CAK77_RS15080 24d6df8d2966ccaf0f99c018d059cce7 228 SUPERFAMILY SSF47979 65 136 3.53E-26 T 06-07-2017 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 CAK77_RS15080 24d6df8d2966ccaf0f99c018d059cce7 228 Gene3D G3DSA:2.30.30.90 134 228 2.7E-32 T 06-07-2017 CAK77_RS15080 24d6df8d2966ccaf0f99c018d059cce7 228 SMART SM00529 26 125 6.5E-48 T 06-07-2017 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 CAK77_RS23260 fba6fe9e76b77b5fdac4c67289d78a4c 396 SUPERFAMILY SSF53383 19 384 1.32E-87 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK77_RS23260 fba6fe9e76b77b5fdac4c67289d78a4c 396 Gene3D G3DSA:3.90.1150.10 258 381 8.0E-32 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK77_RS23260 fba6fe9e76b77b5fdac4c67289d78a4c 396 PIRSF PIRSF005572 16 391 5.3E-108 T 06-07-2017 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 CAK77_RS23260 fba6fe9e76b77b5fdac4c67289d78a4c 396 Pfam PF00266 Aminotransferase class-V 19 375 5.0E-59 T 06-07-2017 IPR000192 Aminotransferase class V domain CAK77_RS23260 fba6fe9e76b77b5fdac4c67289d78a4c 396 Gene3D G3DSA:3.40.640.10 43 257 2.3E-69 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK77_RS06320 09ae6044a215a55d473ba85b6463d69f 754 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 501 631 9.9E-32 T 06-07-2017 IPR025299 CstA, C-terminal domain CAK77_RS06320 09ae6044a215a55d473ba85b6463d69f 754 Pfam PF02554 Carbon starvation protein CstA 65 442 4.3E-165 T 06-07-2017 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 CAK77_RS00790 6972cc758e8d2e985b34d77b175045f4 305 SUPERFAMILY SSF53335 22 297 1.33E-51 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS00790 6972cc758e8d2e985b34d77b175045f4 305 Gene3D G3DSA:3.40.50.150 77 204 2.6E-10 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS00790 6972cc758e8d2e985b34d77b175045f4 305 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 20 275 8.8E-62 T 06-07-2017 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 CAK77_RS00790 6972cc758e8d2e985b34d77b175045f4 305 Pfam PF04072 Leucine carboxyl methyltransferase 20 200 4.1E-41 T 06-07-2017 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 CAK77_RS07535 f094b374840958f57e4428cf0e0557c8 190 SUPERFAMILY SSF48498 74 184 1.07E-13 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS07535 f094b374840958f57e4428cf0e0557c8 190 SUPERFAMILY SSF46689 4 71 2.87E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS07535 f094b374840958f57e4428cf0e0557c8 190 Pfam PF16859 Bacterial transcriptional repressor C-terminal 71 180 9.7E-21 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS07535 f094b374840958f57e4428cf0e0557c8 190 Gene3D G3DSA:1.10.10.60 3 54 1.3E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS07535 f094b374840958f57e4428cf0e0557c8 190 ProSitePatterns PS01081 TetR-type HTH domain signature. 24 55 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CAK77_RS07535 f094b374840958f57e4428cf0e0557c8 190 Gene3D G3DSA:1.10.357.10 55 184 1.3E-20 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS07535 f094b374840958f57e4428cf0e0557c8 190 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 58 7.1E-12 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS18945 c06ce8975d004b6792cbb87084bea03f 179 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 155 163 - T 06-07-2017 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS18945 c06ce8975d004b6792cbb87084bea03f 179 Pfam PF00347 Ribosomal protein L6 11 83 6.6E-17 T 06-07-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK77_RS18945 c06ce8975d004b6792cbb87084bea03f 179 Pfam PF00347 Ribosomal protein L6 91 165 5.8E-20 T 06-07-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK77_RS18945 c06ce8975d004b6792cbb87084bea03f 179 SUPERFAMILY SSF56053 1 83 6.96E-24 T 06-07-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK77_RS18945 c06ce8975d004b6792cbb87084bea03f 179 PRINTS PR00059 Ribosomal protein L6 signature 72 97 1.4E-31 T 06-07-2017 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CAK77_RS18945 c06ce8975d004b6792cbb87084bea03f 179 PRINTS PR00059 Ribosomal protein L6 signature 142 163 1.4E-31 T 06-07-2017 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CAK77_RS18945 c06ce8975d004b6792cbb87084bea03f 179 PRINTS PR00059 Ribosomal protein L6 signature 100 116 1.4E-31 T 06-07-2017 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CAK77_RS18945 c06ce8975d004b6792cbb87084bea03f 179 Gene3D G3DSA:3.90.930.12 84 178 1.5E-37 T 06-07-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK77_RS18945 c06ce8975d004b6792cbb87084bea03f 179 Gene3D G3DSA:3.90.930.12 2 83 5.4E-29 T 06-07-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK77_RS18945 c06ce8975d004b6792cbb87084bea03f 179 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 177 37.665 T 06-07-2017 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CAK77_RS18945 c06ce8975d004b6792cbb87084bea03f 179 SUPERFAMILY SSF56053 84 178 8.24E-35 T 06-07-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK77_RS18945 c06ce8975d004b6792cbb87084bea03f 179 PIRSF PIRSF002162 1 178 5.1E-49 T 06-07-2017 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK77_RS18945 c06ce8975d004b6792cbb87084bea03f 179 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 177 9.1E-72 T 06-07-2017 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CAK77_RS10275 75cd7e151542839c0bd88e776dae143e 281 SUPERFAMILY SSF51679 4 208 7.65E-42 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS10275 75cd7e151542839c0bd88e776dae143e 281 Pfam PF00296 Luciferase-like monooxygenase 13 192 2.9E-33 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS10275 75cd7e151542839c0bd88e776dae143e 281 Gene3D G3DSA:3.20.20.30 3 259 4.9E-46 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS10780 5920d6d281363e9245e7b5ea4ad61388 2121 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 533 831 2.4E-102 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain CAK77_RS10780 5920d6d281363e9245e7b5ea4ad61388 2121 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4 253 1.6E-80 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAK77_RS10780 5920d6d281363e9245e7b5ea4ad61388 2121 SUPERFAMILY SSF55048 656 720 5.23E-11 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CAK77_RS10780 5920d6d281363e9245e7b5ea4ad61388 2121 Pfam PF08659 KR domain 1760 1939 7.3E-57 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAK77_RS10780 5920d6d281363e9245e7b5ea4ad61388 2121 Gene3D G3DSA:3.40.47.10 4 265 6.7E-90 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS10780 5920d6d281363e9245e7b5ea4ad61388 2121 SMART SM00823 Phosphopantetheine attachment site 2038 2109 1.0E-6 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAK77_RS10780 5920d6d281363e9245e7b5ea4ad61388 2121 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1759 1941 1.3E-41 T 06-07-2017 CAK77_RS10780 5920d6d281363e9245e7b5ea4ad61388 2121 Gene3D G3DSA:1.10.1200.10 2036 2101 8.9E-10 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS10780 5920d6d281363e9245e7b5ea4ad61388 2121 SUPERFAMILY SSF51735 1173 1383 1.18E-14 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS10780 5920d6d281363e9245e7b5ea4ad61388 2121 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 382 493 1.9E-16 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAK77_RS10780 5920d6d281363e9245e7b5ea4ad61388 2121 SUPERFAMILY SSF53901 406 427 8.17E-95 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS10780 5920d6d281363e9245e7b5ea4ad61388 2121 SUPERFAMILY SSF53901 4 122 8.17E-95 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS10780 5920d6d281363e9245e7b5ea4ad61388 2121 SUPERFAMILY SSF53901 149 371 8.17E-95 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS10780 5920d6d281363e9245e7b5ea4ad61388 2121 Gene3D G3DSA:3.40.50.720 1759 1943 2.1E-36 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS10780 5920d6d281363e9245e7b5ea4ad61388 2121 SMART SM00826 897 1053 3.0E-31 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAK77_RS10780 5920d6d281363e9245e7b5ea4ad61388 2121 Gene3D G3DSA:3.40.47.10 266 431 3.5E-55 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS10780 5920d6d281363e9245e7b5ea4ad61388 2121 Gene3D G3DSA:3.40.366.10 721 844 2.5E-68 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAK77_RS10780 5920d6d281363e9245e7b5ea4ad61388 2121 Gene3D G3DSA:3.40.366.10 531 653 2.5E-68 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAK77_RS10780 5920d6d281363e9245e7b5ea4ad61388 2121 Gene3D G3DSA:3.30.70.250 655 718 1.2E-4 T 06-07-2017 CAK77_RS10780 5920d6d281363e9245e7b5ea4ad61388 2121 Gene3D G3DSA:3.40.50.720 1531 1711 8.0E-41 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS10780 5920d6d281363e9245e7b5ea4ad61388 2121 Gene3D G3DSA:3.90.180.10 1418 1494 1.1E-8 T 06-07-2017 IPR011032 GroES-like CAK77_RS10780 5920d6d281363e9245e7b5ea4ad61388 2121 SUPERFAMILY SSF50129 1416 1558 1.95E-16 T 06-07-2017 IPR011032 GroES-like CAK77_RS10780 5920d6d281363e9245e7b5ea4ad61388 2121 Pfam PF00698 Acyl transferase domain 531 848 4.5E-68 T 06-07-2017 IPR014043 Acyl transferase CAK77_RS10780 5920d6d281363e9245e7b5ea4ad61388 2121 SUPERFAMILY SSF52151 722 815 3.92E-63 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAK77_RS10780 5920d6d281363e9245e7b5ea4ad61388 2121 SUPERFAMILY SSF52151 531 658 3.92E-63 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAK77_RS10780 5920d6d281363e9245e7b5ea4ad61388 2121 Pfam PF00550 Phosphopantetheine attachment site 2040 2092 1.3E-9 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS10780 5920d6d281363e9245e7b5ea4ad61388 2121 SUPERFAMILY SSF47336 2035 2106 5.89E-11 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS10780 5920d6d281363e9245e7b5ea4ad61388 2121 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 261 376 2.8E-37 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAK77_RS10780 5920d6d281363e9245e7b5ea4ad61388 2121 Pfam PF14765 Polyketide synthase dehydratase 899 1167 9.1E-50 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAK77_RS10780 5920d6d281363e9245e7b5ea4ad61388 2121 SMART SM00825 Beta-ketoacyl synthase 4 431 4.0E-183 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAK77_RS10780 5920d6d281363e9245e7b5ea4ad61388 2121 SUPERFAMILY SSF51735 1756 1990 2.5E-46 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS10780 5920d6d281363e9245e7b5ea4ad61388 2121 SMART SM00829 1413 1736 1.5E-85 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAK77_RS10780 5920d6d281363e9245e7b5ea4ad61388 2121 Pfam PF00107 Zinc-binding dehydrogenase 1565 1663 1.1E-18 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAK77_RS10780 5920d6d281363e9245e7b5ea4ad61388 2121 SUPERFAMILY SSF51735 1534 1697 1.28E-38 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS01520 7a6fbe98ddf1d2184920127bc3a0a376 252 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 136 164 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK77_RS01520 7a6fbe98ddf1d2184920127bc3a0a376 252 Gene3D G3DSA:3.40.50.720 2 249 4.5E-69 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS01520 7a6fbe98ddf1d2184920127bc3a0a376 252 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 7 249 6.3E-51 T 06-07-2017 CAK77_RS01520 7a6fbe98ddf1d2184920127bc3a0a376 252 SUPERFAMILY SSF51735 2 250 1.52E-67 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS01520 7a6fbe98ddf1d2184920127bc3a0a376 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 129 137 4.6E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS01520 7a6fbe98ddf1d2184920127bc3a0a376 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 4.6E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS01520 7a6fbe98ddf1d2184920127bc3a0a376 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 168 4.6E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS01520 7a6fbe98ddf1d2184920127bc3a0a376 252 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 7 24 1.4E-42 T 06-07-2017 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 CAK77_RS01520 7a6fbe98ddf1d2184920127bc3a0a376 252 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 99 119 1.4E-42 T 06-07-2017 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 CAK77_RS01520 7a6fbe98ddf1d2184920127bc3a0a376 252 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 79 96 1.4E-42 T 06-07-2017 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 CAK77_RS01520 7a6fbe98ddf1d2184920127bc3a0a376 252 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 164 187 1.4E-42 T 06-07-2017 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 CAK77_RS01520 7a6fbe98ddf1d2184920127bc3a0a376 252 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 202 221 1.4E-42 T 06-07-2017 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 CAK77_RS01520 7a6fbe98ddf1d2184920127bc3a0a376 252 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 228 247 1.4E-42 T 06-07-2017 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 CAK77_RS08120 1227e4c861790d2776f2df3228ed671b 217 Gene3D G3DSA:1.10.357.10 15 203 1.6E-26 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS08120 1227e4c861790d2776f2df3228ed671b 217 Pfam PF00440 Bacterial regulatory proteins, tetR family 32 74 6.4E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS08120 1227e4c861790d2776f2df3228ed671b 217 SUPERFAMILY SSF46689 20 91 3.64E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS10890 d60b1e25c71dad92399c669d837e5a4b 620 SMART SM00382 364 503 1.2E-5 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS10890 d60b1e25c71dad92399c669d837e5a4b 620 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 369 500 4.0E-19 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 CAK77_RS10890 d60b1e25c71dad92399c669d837e5a4b 620 Gene3D G3DSA:3.40.50.300 325 515 2.2E-26 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS10890 d60b1e25c71dad92399c669d837e5a4b 620 SUPERFAMILY SSF52540 322 536 2.89E-33 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS10890 d60b1e25c71dad92399c669d837e5a4b 620 Gene3D G3DSA:1.25.40.10 7 81 4.6E-7 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK77_RS10890 d60b1e25c71dad92399c669d837e5a4b 620 Gene3D G3DSA:1.25.40.10 130 275 4.6E-7 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK77_RS10890 d60b1e25c71dad92399c669d837e5a4b 620 SUPERFAMILY SSF48452 96 110 3.42E-5 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK77_RS10890 d60b1e25c71dad92399c669d837e5a4b 620 SUPERFAMILY SSF48452 141 224 3.42E-5 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK77_RS10890 d60b1e25c71dad92399c669d837e5a4b 620 PRINTS PR00819 CbxX/CfqX superfamily signature 558 570 1.3E-53 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 CAK77_RS10890 d60b1e25c71dad92399c669d837e5a4b 620 PRINTS PR00819 CbxX/CfqX superfamily signature 367 382 1.3E-53 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 CAK77_RS10890 d60b1e25c71dad92399c669d837e5a4b 620 PRINTS PR00819 CbxX/CfqX superfamily signature 450 462 1.3E-53 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 CAK77_RS10890 d60b1e25c71dad92399c669d837e5a4b 620 PRINTS PR00819 CbxX/CfqX superfamily signature 419 438 1.3E-53 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 CAK77_RS10890 d60b1e25c71dad92399c669d837e5a4b 620 PRINTS PR00819 CbxX/CfqX superfamily signature 327 341 1.3E-53 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 CAK77_RS10890 d60b1e25c71dad92399c669d837e5a4b 620 PRINTS PR00819 CbxX/CfqX superfamily signature 471 488 1.3E-53 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 CAK77_RS10890 d60b1e25c71dad92399c669d837e5a4b 620 PRINTS PR00819 CbxX/CfqX superfamily signature 405 419 1.3E-53 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 CAK77_RS10890 d60b1e25c71dad92399c669d837e5a4b 620 PRINTS PR00819 CbxX/CfqX superfamily signature 488 507 1.3E-53 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 CAK77_RS10890 d60b1e25c71dad92399c669d837e5a4b 620 TIGRFAM TIGR03922 T7SS_EccA: type VII secretion AAA-ATPase EccA 58 605 1.2E-232 T 06-07-2017 IPR023835 Type VII secretion system AAA-ATPase, EccA CAK77_RS18820 a771bb44244cfc0be533042ba1a912ee 124 Gene3D G3DSA:1.10.8.50 1 72 4.6E-31 T 06-07-2017 CAK77_RS18820 a771bb44244cfc0be533042ba1a912ee 124 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 120 28.292 T 06-07-2017 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK77_RS18820 a771bb44244cfc0be533042ba1a912ee 124 Gene3D G3DSA:4.10.910.10 73 122 4.1E-27 T 06-07-2017 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK77_RS18820 a771bb44244cfc0be533042ba1a912ee 124 Pfam PF00416 Ribosomal protein S13/S18 3 109 1.4E-34 T 06-07-2017 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK77_RS18820 a771bb44244cfc0be533042ba1a912ee 124 PIRSF PIRSF002134 1 124 5.3E-46 T 06-07-2017 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK77_RS18820 a771bb44244cfc0be533042ba1a912ee 124 SUPERFAMILY SSF46946 2 121 2.49E-47 T 06-07-2017 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 CAK77_RS18820 a771bb44244cfc0be533042ba1a912ee 124 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 115 2.0E-53 T 06-07-2017 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS18820 a771bb44244cfc0be533042ba1a912ee 124 ProSitePatterns PS00646 Ribosomal protein S13 signature. 88 101 - T 06-07-2017 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK77_RS08430 aa5b1f58aef7e56ffc223ec7f5f77503 296 Gene3D G3DSA:1.10.3720.10 44 292 3.5E-48 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS08430 aa5b1f58aef7e56ffc223ec7f5f77503 296 TIGRFAM TIGR02139 permease_CysT: sulfate ABC transporter, permease protein CysT 40 288 4.2E-82 T 06-07-2017 IPR011865 Sulphate ABC transporter, permease protein CysT GO:0008272|GO:0015116|GO:0016021 CAK77_RS08430 aa5b1f58aef7e56ffc223ec7f5f77503 296 TIGRFAM TIGR00969 3a0106s02: sulfate ABC transporter, permease protein 41 284 1.7E-76 T 06-07-2017 IPR005667 Sulphate ABC transporter permease protein 2 GO:0008272|GO:0015419|GO:0016020 CAK77_RS08430 aa5b1f58aef7e56ffc223ec7f5f77503 296 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 101 287 3.1E-26 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS08430 aa5b1f58aef7e56ffc223ec7f5f77503 296 SUPERFAMILY SSF161098 42 282 2.09E-50 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS14090 f658e3be6beb271f9293182282ab2ead 588 SUPERFAMILY SSF82866 361 557 2.49E-29 T 06-07-2017 CAK77_RS14090 f658e3be6beb271f9293182282ab2ead 588 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 40 555 3.3E-135 T 06-07-2017 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 CAK77_RS14090 f658e3be6beb271f9293182282ab2ead 588 Pfam PF07549 SecD/SecF GG Motif 38 57 2.7E-4 T 06-07-2017 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site CAK77_RS14090 f658e3be6beb271f9293182282ab2ead 588 Gene3D G3DSA:1.20.1640.10 359 557 3.4E-19 T 06-07-2017 CAK77_RS14090 f658e3be6beb271f9293182282ab2ead 588 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 312 547 1.7E-70 T 06-07-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CAK77_RS14090 f658e3be6beb271f9293182282ab2ead 588 Pfam PF02355 Protein export membrane protein 383 556 1.5E-8 T 06-07-2017 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial CAK77_RS14090 f658e3be6beb271f9293182282ab2ead 588 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 2 568 37.32 T 06-07-2017 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 CAK77_RS14130 723500672d1e75ca7e1ec73268f32bb2 251 Gene3D G3DSA:1.10.10.200 1 79 3.2E-32 T 06-07-2017 IPR017856 Integrase, N-terminal zinc-binding domain-like CAK77_RS14130 723500672d1e75ca7e1ec73268f32bb2 251 Gene3D G3DSA:3.30.1270.10 213 248 6.2E-39 T 06-07-2017 IPR026563 Transcriptional regulator TACO1-like, domain 2 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK77_RS14130 723500672d1e75ca7e1ec73268f32bb2 251 Gene3D G3DSA:3.30.1270.10 84 137 6.2E-39 T 06-07-2017 IPR026563 Transcriptional regulator TACO1-like, domain 2 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK77_RS14130 723500672d1e75ca7e1ec73268f32bb2 251 Gene3D G3DSA:3.30.70.980 138 205 5.9E-25 T 06-07-2017 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK77_RS14130 723500672d1e75ca7e1ec73268f32bb2 251 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 238 3.4E-100 T 06-07-2017 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK77_RS14130 723500672d1e75ca7e1ec73268f32bb2 251 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 3 240 34.707 T 06-07-2017 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK77_RS14130 723500672d1e75ca7e1ec73268f32bb2 251 SUPERFAMILY SSF75625 3 246 1.7E-89 T 06-07-2017 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK77_RS14130 723500672d1e75ca7e1ec73268f32bb2 251 Pfam PF01709 Transcriptional regulator 5 238 5.2E-88 T 06-07-2017 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK77_RS03095 affca909a2a87a8507b88f8354241a99 380 Gene3D G3DSA:1.10.540.10 3 116 1.5E-20 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS03095 affca909a2a87a8507b88f8354241a99 380 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 124 217 1.3E-22 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAK77_RS03095 affca909a2a87a8507b88f8354241a99 380 SUPERFAMILY SSF47203 230 375 1.45E-20 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS03095 affca909a2a87a8507b88f8354241a99 380 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 4 116 4.0E-18 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS03095 affca909a2a87a8507b88f8354241a99 380 Gene3D G3DSA:2.40.110.10 123 219 1.6E-34 T 06-07-2017 CAK77_RS03095 affca909a2a87a8507b88f8354241a99 380 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 230 373 4.2E-26 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS03095 affca909a2a87a8507b88f8354241a99 380 SUPERFAMILY SSF56645 6 241 2.09E-65 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK77_RS03095 affca909a2a87a8507b88f8354241a99 380 Gene3D G3DSA:1.20.140.10 220 378 2.0E-26 T 06-07-2017 CAK77_RS10550 437d9568d74c103dc2e74f914322cabc 337 Gene3D G3DSA:3.40.47.10 1 169 4.0E-21 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS10550 437d9568d74c103dc2e74f914322cabc 337 SUPERFAMILY SSF53901 5 332 1.1E-28 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS10550 437d9568d74c103dc2e74f914322cabc 337 Gene3D G3DSA:3.40.47.10 170 333 3.1E-25 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS10550 437d9568d74c103dc2e74f914322cabc 337 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 112 187 4.1E-8 T 06-07-2017 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CAK77_RS10550 437d9568d74c103dc2e74f914322cabc 337 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 242 332 2.3E-20 T 06-07-2017 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CAK77_RS03710 4a2be5a9118ca2429813ffff99dc0e00 528 Gene3D G3DSA:3.90.76.10 41 201 2.0E-23 T 06-07-2017 CAK77_RS03710 4a2be5a9118ca2429813ffff99dc0e00 528 Gene3D G3DSA:3.10.105.10 279 488 1.2E-35 T 06-07-2017 CAK77_RS03710 4a2be5a9118ca2429813ffff99dc0e00 528 PIRSF PIRSF002741 7 520 6.1E-56 T 06-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CAK77_RS03710 4a2be5a9118ca2429813ffff99dc0e00 528 SUPERFAMILY SSF53850 28 521 1.81E-86 T 06-07-2017 CAK77_RS03710 4a2be5a9118ca2429813ffff99dc0e00 528 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 75 443 3.0E-58 T 06-07-2017 IPR000914 Solute-binding protein family 5 domain CAK77_RS03900 6d18c3cdd50ab0d63d4fa58dc5d6accf 332 Pfam PF00355 Rieske [2Fe-2S] domain 13 95 1.7E-15 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK77_RS03900 6d18c3cdd50ab0d63d4fa58dc5d6accf 332 SUPERFAMILY SSF50022 10 119 5.24E-30 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK77_RS03900 6d18c3cdd50ab0d63d4fa58dc5d6accf 332 Gene3D G3DSA:2.102.10.10 12 124 2.5E-29 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK77_RS03900 6d18c3cdd50ab0d63d4fa58dc5d6accf 332 SUPERFAMILY SSF55961 101 329 2.58E-14 T 06-07-2017 CAK77_RS11810 936395a4fdf182f6043c032711afbb56 227 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 7 222 6.2E-25 T 06-07-2017 CAK77_RS11810 936395a4fdf182f6043c032711afbb56 227 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 2 19 5.7E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS11810 936395a4fdf182f6043c032711afbb56 227 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 141 160 5.7E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS11810 936395a4fdf182f6043c032711afbb56 227 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 179 5.7E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS11810 936395a4fdf182f6043c032711afbb56 227 SUPERFAMILY SSF51735 3 222 4.31E-37 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS11810 936395a4fdf182f6043c032711afbb56 227 Gene3D G3DSA:3.40.50.720 3 222 1.0E-34 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS10845 54e9d3d1eeaf7b090b6e5d59e5b74f40 461 PRINTS PR00723 Subtilisin serine protease family (S8) signature 92 111 1.2E-11 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related CAK77_RS10845 54e9d3d1eeaf7b090b6e5d59e5b74f40 461 PRINTS PR00723 Subtilisin serine protease family (S8) signature 340 356 1.2E-11 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related CAK77_RS10845 54e9d3d1eeaf7b090b6e5d59e5b74f40 461 PRINTS PR00723 Subtilisin serine protease family (S8) signature 127 140 1.2E-11 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related CAK77_RS10845 54e9d3d1eeaf7b090b6e5d59e5b74f40 461 Pfam PF00082 Subtilase family 92 390 1.5E-30 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CAK77_RS10845 54e9d3d1eeaf7b090b6e5d59e5b74f40 461 SUPERFAMILY SSF52743 83 399 6.41E-57 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CAK77_RS10845 54e9d3d1eeaf7b090b6e5d59e5b74f40 461 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 131 141 - T 06-07-2017 IPR022398 Peptidase S8, subtilisin, His-active site CAK77_RS10845 54e9d3d1eeaf7b090b6e5d59e5b74f40 461 TIGRFAM TIGR03921 T7SS_mycosin: type VII secretion-associated serine protease mycosin 82 457 2.2E-117 T 06-07-2017 IPR023834 Type VII secretion system peptidase S8A, mycosin-1 CAK77_RS10845 54e9d3d1eeaf7b090b6e5d59e5b74f40 461 Gene3D G3DSA:3.40.50.200 80 399 9.7E-61 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CAK77_RS24085 798b287863a079ca3e86e7647d6209a9 84 Gene3D G3DSA:4.10.640.10 18 80 2.3E-29 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS24085 798b287863a079ca3e86e7647d6209a9 84 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 3 82 20.056 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS24085 798b287863a079ca3e86e7647d6209a9 84 TIGRFAM TIGR00165 S18: ribosomal protein bS18 16 80 2.5E-26 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS24085 798b287863a079ca3e86e7647d6209a9 84 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 30 81 3.0E-23 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS24085 798b287863a079ca3e86e7647d6209a9 84 PRINTS PR00974 Ribosomal protein S18 family signature 37 47 1.6E-16 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS24085 798b287863a079ca3e86e7647d6209a9 84 PRINTS PR00974 Ribosomal protein S18 family signature 69 79 1.6E-16 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS24085 798b287863a079ca3e86e7647d6209a9 84 PRINTS PR00974 Ribosomal protein S18 family signature 47 54 1.6E-16 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS24085 798b287863a079ca3e86e7647d6209a9 84 PRINTS PR00974 Ribosomal protein S18 family signature 55 69 1.6E-16 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS24085 798b287863a079ca3e86e7647d6209a9 84 Pfam PF01084 Ribosomal protein S18 27 77 6.3E-23 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS24085 798b287863a079ca3e86e7647d6209a9 84 ProSitePatterns PS00057 Ribosomal protein S18 signature. 30 53 - T 06-07-2017 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS24085 798b287863a079ca3e86e7647d6209a9 84 SUPERFAMILY SSF46911 9 80 2.09E-25 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS13705 eb0036f67b9cfa457e58bbe57dcdf28b 343 SUPERFAMILY SSF55021 265 337 4.69E-8 T 06-07-2017 CAK77_RS13705 eb0036f67b9cfa457e58bbe57dcdf28b 343 Gene3D G3DSA:3.30.70.260 242 334 3.5E-9 T 06-07-2017 CAK77_RS13705 eb0036f67b9cfa457e58bbe57dcdf28b 343 SUPERFAMILY SSF52540 7 244 6.05E-84 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS13705 eb0036f67b9cfa457e58bbe57dcdf28b 343 SMART SM00382 36 223 2.3E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS13705 eb0036f67b9cfa457e58bbe57dcdf28b 343 Pfam PF00005 ABC transporter 28 175 5.8E-34 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK77_RS13705 eb0036f67b9cfa457e58bbe57dcdf28b 343 SMART SM00930 268 341 4.2E-6 T 06-07-2017 IPR018449 NIL domain CAK77_RS13705 eb0036f67b9cfa457e58bbe57dcdf28b 343 Gene3D G3DSA:3.40.50.300 6 241 7.0E-85 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS13705 eb0036f67b9cfa457e58bbe57dcdf28b 343 Pfam PF09383 NIL domain 289 332 9.8E-7 T 06-07-2017 IPR018449 NIL domain CAK77_RS13705 eb0036f67b9cfa457e58bbe57dcdf28b 343 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK77_RS18370 33598c4b84ec3fae9b4a16913f62feba 384 Gene3D G3DSA:3.40.50.1820 36 207 1.5E-30 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS18370 33598c4b84ec3fae9b4a16913f62feba 384 Gene3D G3DSA:3.40.50.1820 250 375 1.5E-30 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS18370 33598c4b84ec3fae9b4a16913f62feba 384 TIGRFAM TIGR01392 homoserO_Ac_trn: homoserine O-acetyltransferase 27 375 1.6E-129 T 06-07-2017 IPR008220 Homoserine acetyltransferase GO:0004414|GO:0005737|GO:0009086 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 CAK77_RS18370 33598c4b84ec3fae9b4a16913f62feba 384 PIRSF PIRSF000443 12 383 5.5E-114 T 06-07-2017 IPR008220 Homoserine acetyltransferase GO:0004414|GO:0005737|GO:0009086 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 CAK77_RS18370 33598c4b84ec3fae9b4a16913f62feba 384 SUPERFAMILY SSF53474 20 375 3.41E-88 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS18370 33598c4b84ec3fae9b4a16913f62feba 384 Pfam PF00561 alpha/beta hydrolase fold 55 363 1.7E-28 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS18370 33598c4b84ec3fae9b4a16913f62feba 384 Hamap MF_00296 Homoserine O-acetyltransferase [metX]. 10 377 45.068 T 06-07-2017 IPR008220 Homoserine acetyltransferase GO:0004414|GO:0005737|GO:0009086 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 CAK77_RS07660 333242498e5aff695b714edadafbda41 405 Pfam PF07730 Histidine kinase 184 248 7.2E-14 T 06-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CAK77_RS07660 333242498e5aff695b714edadafbda41 405 SUPERFAMILY SSF55874 275 380 8.21E-6 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS03500 f3d24a07451678f0f59ad7a666fd0ebe 487 SUPERFAMILY SSF55874 285 449 4.98E-42 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS03500 f3d24a07451678f0f59ad7a666fd0ebe 487 SMART SM00304 164 217 8.1E-11 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAK77_RS03500 f3d24a07451678f0f59ad7a666fd0ebe 487 SMART SM00388 232 296 4.5E-19 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK77_RS03500 f3d24a07451678f0f59ad7a666fd0ebe 487 PRINTS PR00344 Bacterial sensor protein C-terminal signature 435 448 4.9E-16 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK77_RS03500 f3d24a07451678f0f59ad7a666fd0ebe 487 PRINTS PR00344 Bacterial sensor protein C-terminal signature 411 429 4.9E-16 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK77_RS03500 f3d24a07451678f0f59ad7a666fd0ebe 487 PRINTS PR00344 Bacterial sensor protein C-terminal signature 376 390 4.9E-16 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK77_RS03500 f3d24a07451678f0f59ad7a666fd0ebe 487 PRINTS PR00344 Bacterial sensor protein C-terminal signature 394 404 4.9E-16 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK77_RS03500 f3d24a07451678f0f59ad7a666fd0ebe 487 SUPERFAMILY SSF158472 167 214 1.14E-7 T 06-07-2017 CAK77_RS03500 f3d24a07451678f0f59ad7a666fd0ebe 487 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 341 449 1.9E-26 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS03500 f3d24a07451678f0f59ad7a666fd0ebe 487 SUPERFAMILY SSF47384 223 296 3.92E-17 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK77_RS03500 f3d24a07451678f0f59ad7a666fd0ebe 487 Gene3D G3DSA:1.10.287.130 224 292 3.7E-17 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK77_RS03500 f3d24a07451678f0f59ad7a666fd0ebe 487 Pfam PF00672 HAMP domain 145 214 4.5E-14 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAK77_RS03500 f3d24a07451678f0f59ad7a666fd0ebe 487 Gene3D G3DSA:3.30.565.10 298 456 2.6E-45 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS03500 f3d24a07451678f0f59ad7a666fd0ebe 487 SMART SM00387 341 451 4.5E-37 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS03500 f3d24a07451678f0f59ad7a666fd0ebe 487 Pfam PF00512 His Kinase A (phospho-acceptor) domain 233 295 1.1E-16 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK77_RS14995 f41881911959bb8c73960c4b244c312a 177 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 135 141 - T 06-07-2017 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CAK77_RS14995 f41881911959bb8c73960c4b244c312a 177 SUPERFAMILY SSF46767 85 167 8.63E-24 T 06-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CAK77_RS14995 f41881911959bb8c73960c4b244c312a 177 SUPERFAMILY SSF53155 4 80 4.51E-12 T 06-07-2017 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CAK77_RS14995 f41881911959bb8c73960c4b244c312a 177 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 85 166 3.0E-24 T 06-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CAK77_RS14995 f41881911959bb8c73960c4b244c312a 177 Gene3D G3DSA:3.30.160.70 3 72 7.2E-8 T 06-07-2017 CAK77_RS14995 f41881911959bb8c73960c4b244c312a 177 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 87 167 2.0E-26 T 06-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CAK77_RS14995 f41881911959bb8c73960c4b244c312a 177 Gene3D G3DSA:1.10.10.10 85 167 2.0E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS08190 cb760d96eac8a039836d20b1e06c6641 879 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 814 878 1.1E-16 T 06-07-2017 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 CAK77_RS08190 cb760d96eac8a039836d20b1e06c6641 879 SUPERFAMILY SSF47323 589 827 2.43E-48 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK77_RS08190 cb760d96eac8a039836d20b1e06c6641 879 Gene3D G3DSA:3.90.740.10 205 346 3.5E-44 T 06-07-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CAK77_RS08190 cb760d96eac8a039836d20b1e06c6641 879 Gene3D G3DSA:1.10.287.380 809 878 4.0E-8 T 06-07-2017 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 CAK77_RS08190 cb760d96eac8a039836d20b1e06c6641 879 PRINTS PR00986 Valyl-tRNA synthetase signature 358 371 1.4E-38 T 06-07-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CAK77_RS08190 cb760d96eac8a039836d20b1e06c6641 879 PRINTS PR00986 Valyl-tRNA synthetase signature 481 499 1.4E-38 T 06-07-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CAK77_RS08190 cb760d96eac8a039836d20b1e06c6641 879 PRINTS PR00986 Valyl-tRNA synthetase signature 47 58 1.4E-38 T 06-07-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CAK77_RS08190 cb760d96eac8a039836d20b1e06c6641 879 PRINTS PR00986 Valyl-tRNA synthetase signature 242 259 1.4E-38 T 06-07-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CAK77_RS08190 cb760d96eac8a039836d20b1e06c6641 879 PRINTS PR00986 Valyl-tRNA synthetase signature 450 471 1.4E-38 T 06-07-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CAK77_RS08190 cb760d96eac8a039836d20b1e06c6641 879 SUPERFAMILY SSF46589 814 878 7.85E-14 T 06-07-2017 IPR010978 tRNA-binding arm GO:0000166 CAK77_RS08190 cb760d96eac8a039836d20b1e06c6641 879 Gene3D G3DSA:3.40.50.620 353 573 1.3E-133 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS08190 cb760d96eac8a039836d20b1e06c6641 879 Gene3D G3DSA:3.40.50.620 18 204 1.3E-133 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS08190 cb760d96eac8a039836d20b1e06c6641 879 Pfam PF08264 Anticodon-binding domain of tRNA 617 756 2.4E-37 T 06-07-2017 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CAK77_RS08190 cb760d96eac8a039836d20b1e06c6641 879 Gene3D G3DSA:1.10.730.10 580 748 1.2E-51 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK77_RS08190 cb760d96eac8a039836d20b1e06c6641 879 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 26 574 3.4E-190 T 06-07-2017 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK77_RS08190 cb760d96eac8a039836d20b1e06c6641 879 TIGRFAM TIGR00422 valS: valine--tRNA ligase 14 859 2.8E-298 T 06-07-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CAK77_RS08190 cb760d96eac8a039836d20b1e06c6641 879 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 54 65 - T 06-07-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK77_RS08190 cb760d96eac8a039836d20b1e06c6641 879 SUPERFAMILY SSF50677 202 346 5.36E-54 T 06-07-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CAK77_RS08190 cb760d96eac8a039836d20b1e06c6641 879 Hamap MF_02004 Valine--tRNA ligase [valS]. 13 879 14.878 T 06-07-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CAK77_RS08190 cb760d96eac8a039836d20b1e06c6641 879 SUPERFAMILY SSF52374 353 586 9.75E-130 T 06-07-2017 CAK77_RS08190 cb760d96eac8a039836d20b1e06c6641 879 SUPERFAMILY SSF52374 13 203 9.75E-130 T 06-07-2017 CAK77_RS13140 d6a4bf0f7af1bd46108b9af7ebcc293a 306 Gene3D G3DSA:3.40.190.10 186 267 4.3E-23 T 06-07-2017 CAK77_RS13140 d6a4bf0f7af1bd46108b9af7ebcc293a 306 Pfam PF03466 LysR substrate binding domain 94 293 1.2E-41 T 06-07-2017 IPR005119 LysR, substrate-binding CAK77_RS13140 d6a4bf0f7af1bd46108b9af7ebcc293a 306 SUPERFAMILY SSF53850 95 297 1.33E-38 T 06-07-2017 CAK77_RS13140 d6a4bf0f7af1bd46108b9af7ebcc293a 306 Gene3D G3DSA:3.40.190.10 96 185 2.5E-22 T 06-07-2017 CAK77_RS13140 d6a4bf0f7af1bd46108b9af7ebcc293a 306 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 68 1.8E-14 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK77_RS13140 d6a4bf0f7af1bd46108b9af7ebcc293a 306 Gene3D G3DSA:1.10.10.10 11 90 2.7E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS13140 d6a4bf0f7af1bd46108b9af7ebcc293a 306 SUPERFAMILY SSF46785 12 118 2.08E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS07430 971d8110068b6500ffb43320af701411 330 SUPERFAMILY SSF56266 6 326 1.6E-75 T 06-07-2017 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CAK77_RS07430 971d8110068b6500ffb43320af701411 330 Pfam PF03576 Peptidase family S58 7 317 3.8E-69 T 06-07-2017 IPR005321 Peptidase S58, DmpA CAK77_RS07430 971d8110068b6500ffb43320af701411 330 Gene3D G3DSA:3.60.70.12 6 322 5.0E-88 T 06-07-2017 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CAK77_RS09880 7bb48a4f428c59896c537efb44534c5e 429 Pfam PF00668 Condensation domain 40 175 8.7E-6 T 06-07-2017 IPR001242 Condensation domain CAK77_RS09880 7bb48a4f428c59896c537efb44534c5e 429 Pfam PF16911 Phthiocerol/phthiodiolone dimycocerosyl transferase C-terminus 301 422 4.9E-30 T 06-07-2017 IPR031641 Phthiocerol/phthiodiolone dimycocerosyl transferase, C-terminal CAK77_RS09880 7bb48a4f428c59896c537efb44534c5e 429 SUPERFAMILY SSF52777 15 161 1.22E-12 T 06-07-2017 CAK77_RS09880 7bb48a4f428c59896c537efb44534c5e 429 SUPERFAMILY SSF52777 205 426 3.78E-27 T 06-07-2017 CAK77_RS23935 2d173dfaaffba325d112d6150d35396d 63 Gene3D G3DSA:1.25.40.10 3 49 4.2E-5 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK77_RS23755 700e6205e4446e86935fa8e0c9076309 943 SUPERFAMILY SSF82866 720 929 8.76E-31 T 06-07-2017 CAK77_RS23755 700e6205e4446e86935fa8e0c9076309 943 SUPERFAMILY SSF82866 152 350 7.19E-28 T 06-07-2017 CAK77_RS23755 700e6205e4446e86935fa8e0c9076309 943 Pfam PF03176 MMPL family 638 938 4.2E-84 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 CAK77_RS23755 700e6205e4446e86935fa8e0c9076309 943 Pfam PF03176 MMPL family 55 382 4.3E-99 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 CAK77_RS23755 700e6205e4446e86935fa8e0c9076309 943 Gene3D G3DSA:1.20.1640.10 150 350 5.3E-28 T 06-07-2017 CAK77_RS23755 700e6205e4446e86935fa8e0c9076309 943 Gene3D G3DSA:1.20.1640.10 729 930 2.3E-23 T 06-07-2017 CAK77_RS23755 700e6205e4446e86935fa8e0c9076309 943 TIGRFAM TIGR00833 actII: transport protein 21 929 7.9E-278 T 06-07-2017 IPR004707 Membrane transport protein MmpL family GO:0016021 CAK77_RS11475 c20c108e693205194a92c1a57101a68d 334 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 13 233 1.3E-29 T 06-07-2017 IPR006357 HAD-superfamily hydrolase, subfamily IIA CAK77_RS11475 c20c108e693205194a92c1a57101a68d 334 Pfam PF13242 HAD-hyrolase-like 186 256 1.7E-13 T 06-07-2017 CAK77_RS11475 c20c108e693205194a92c1a57101a68d 334 Gene3D G3DSA:3.40.50.1000 185 259 2.6E-27 T 06-07-2017 IPR023214 HAD-like domain CAK77_RS11475 c20c108e693205194a92c1a57101a68d 334 Gene3D G3DSA:3.40.50.1000 6 79 2.6E-27 T 06-07-2017 IPR023214 HAD-like domain CAK77_RS11475 c20c108e693205194a92c1a57101a68d 334 SUPERFAMILY SSF56784 8 259 8.26E-48 T 06-07-2017 IPR023214 HAD-like domain CAK77_RS11475 c20c108e693205194a92c1a57101a68d 334 Pfam PF13344 Haloacid dehalogenase-like hydrolase 12 110 2.1E-18 T 06-07-2017 IPR006357 HAD-superfamily hydrolase, subfamily IIA CAK77_RS11475 c20c108e693205194a92c1a57101a68d 334 Gene3D G3DSA:3.40.50.10410 80 184 9.2E-30 T 06-07-2017 IPR023215 Nitrophenylphosphatase-like domain CAK77_RS18695 0fb841289175aeed6f37a5ee93c79469 345 Gene3D G3DSA:3.20.20.30 1 343 1.1E-64 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS18695 0fb841289175aeed6f37a5ee93c79469 345 SUPERFAMILY SSF51679 1 343 1.47E-61 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS18695 0fb841289175aeed6f37a5ee93c79469 345 TIGRFAM TIGR03559 F420_Rv3520c: probable F420-dependent oxidoreductase, Rv3520c family 2 324 3.1E-159 T 06-07-2017 IPR019951 F420-dependent oxidoreductase-predicted, Rv3520c CAK77_RS18695 0fb841289175aeed6f37a5ee93c79469 345 Pfam PF00296 Luciferase-like monooxygenase 4 320 2.9E-71 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS22970 1ac62a4ff29027ed75f03f7d9d3ad4ef 395 SUPERFAMILY SSF103473 8 388 3.79E-36 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK77_RS22970 1ac62a4ff29027ed75f03f7d9d3ad4ef 395 Pfam PF07690 Major Facilitator Superfamily 253 382 4.1E-11 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK77_RS22970 1ac62a4ff29027ed75f03f7d9d3ad4ef 395 Pfam PF07690 Major Facilitator Superfamily 34 239 2.8E-16 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK77_RS22970 1ac62a4ff29027ed75f03f7d9d3ad4ef 395 Gene3D G3DSA:1.20.1250.20 218 386 2.6E-14 T 06-07-2017 CAK77_RS22970 1ac62a4ff29027ed75f03f7d9d3ad4ef 395 Gene3D G3DSA:1.20.1250.20 11 197 1.4E-14 T 06-07-2017 CAK77_RS10765 7dfc2ff1fc7039f8b723409e65f8315d 322 Pfam PF04072 Leucine carboxyl methyltransferase 42 224 5.1E-42 T 06-07-2017 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 CAK77_RS10765 7dfc2ff1fc7039f8b723409e65f8315d 322 SUPERFAMILY SSF53335 36 301 4.07E-57 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS10765 7dfc2ff1fc7039f8b723409e65f8315d 322 Gene3D G3DSA:3.40.50.150 103 239 9.0E-17 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS10765 7dfc2ff1fc7039f8b723409e65f8315d 322 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 38 301 8.4E-55 T 06-07-2017 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 CAK77_RS06175 b526bafe9841c7ea6d2803dd8d2bd722 302 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 22 270 1.6E-48 T 06-07-2017 IPR018713 Domain of unknown function DUF2236 CAK77_RS13940 d3fc28bb66d950b765c94c6471767977 166 Pfam PF03652 Holliday junction resolvase 21 154 5.8E-43 T 06-07-2017 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 CAK77_RS13940 d3fc28bb66d950b765c94c6471767977 166 SUPERFAMILY SSF53098 20 156 2.73E-35 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAK77_RS13940 d3fc28bb66d950b765c94c6471767977 166 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 23 154 3.8E-31 T 06-07-2017 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 CAK77_RS13940 d3fc28bb66d950b765c94c6471767977 166 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 20 157 23.487 T 06-07-2017 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 CAK77_RS13940 d3fc28bb66d950b765c94c6471767977 166 Gene3D G3DSA:3.30.420.140 19 159 2.0E-47 T 06-07-2017 IPR006641 YqgF/RNase H-like domain GO:0006139 CAK77_RS13940 d3fc28bb66d950b765c94c6471767977 166 SMART SM00732 20 122 4.7E-25 T 06-07-2017 IPR006641 YqgF/RNase H-like domain GO:0006139 CAK77_RS12980 4aea30eb1c68ad0057c80a9cabccea3e 267 SUPERFAMILY SSF54637 2 94 3.31E-23 T 06-07-2017 IPR029069 HotDog domain CAK77_RS12980 4aea30eb1c68ad0057c80a9cabccea3e 267 Gene3D G3DSA:3.10.129.10 1 90 4.6E-26 T 06-07-2017 IPR029069 HotDog domain CAK77_RS12980 4aea30eb1c68ad0057c80a9cabccea3e 267 SUPERFAMILY SSF54637 96 260 2.49E-43 T 06-07-2017 IPR029069 HotDog domain CAK77_RS12980 4aea30eb1c68ad0057c80a9cabccea3e 267 Gene3D G3DSA:3.10.129.10 105 262 2.2E-44 T 06-07-2017 IPR029069 HotDog domain CAK77_RS12980 4aea30eb1c68ad0057c80a9cabccea3e 267 Pfam PF13622 Thioesterase-like superfamily 6 260 5.6E-46 T 06-07-2017 CAK77_RS18235 8957b3e08c18cb4d738e79c029fb3f93 537 SUPERFAMILY SSF53738 195 294 9.42E-19 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK77_RS18235 8957b3e08c18cb4d738e79c029fb3f93 537 Gene3D G3DSA:3.40.120.10 25 201 4.1E-55 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK77_RS18235 8957b3e08c18cb4d738e79c029fb3f93 537 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 306 417 2.9E-18 T 06-07-2017 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK77_RS18235 8957b3e08c18cb4d738e79c029fb3f93 537 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 41 176 6.2E-41 T 06-07-2017 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK77_RS18235 8957b3e08c18cb4d738e79c029fb3f93 537 Gene3D G3DSA:3.40.120.10 290 427 8.5E-33 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK77_RS18235 8957b3e08c18cb4d738e79c029fb3f93 537 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 136 145 - T 06-07-2017 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK77_RS18235 8957b3e08c18cb4d738e79c029fb3f93 537 Gene3D G3DSA:3.40.120.10 212 289 4.5E-19 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK77_RS18235 8957b3e08c18cb4d738e79c029fb3f93 537 SUPERFAMILY SSF53738 286 419 3.69E-24 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK77_RS18235 8957b3e08c18cb4d738e79c029fb3f93 537 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 211 230 6.2E-9 T 06-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK77_RS18235 8957b3e08c18cb4d738e79c029fb3f93 537 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 278 293 6.2E-9 T 06-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK77_RS18235 8957b3e08c18cb4d738e79c029fb3f93 537 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 135 149 6.2E-9 T 06-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK77_RS18235 8957b3e08c18cb4d738e79c029fb3f93 537 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 198 293 9.5E-21 T 06-07-2017 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK77_RS18235 8957b3e08c18cb4d738e79c029fb3f93 537 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 488 509 1.1E-5 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK77_RS18235 8957b3e08c18cb4d738e79c029fb3f93 537 SUPERFAMILY SSF55957 426 516 3.79E-9 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK77_RS18235 8957b3e08c18cb4d738e79c029fb3f93 537 Gene3D G3DSA:3.30.310.50 449 510 1.6E-11 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK77_RS18235 8957b3e08c18cb4d738e79c029fb3f93 537 SUPERFAMILY SSF53738 31 200 2.39E-43 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK77_RS23685 b44767ea48c384c761cf9934c82dceec 319 Pfam PF01965 DJ-1/PfpI family 7 173 1.1E-27 T 06-07-2017 IPR002818 DJ-1/PfpI CAK77_RS23685 b44767ea48c384c761cf9934c82dceec 319 SUPERFAMILY SSF46689 215 262 7.17E-7 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS23685 b44767ea48c384c761cf9934c82dceec 319 Gene3D G3DSA:1.10.10.60 276 315 7.2E-8 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS23685 b44767ea48c384c761cf9934c82dceec 319 SUPERFAMILY SSF46689 266 315 1.34E-6 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS23685 b44767ea48c384c761cf9934c82dceec 319 Gene3D G3DSA:1.10.10.60 218 268 2.0E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS23685 b44767ea48c384c761cf9934c82dceec 319 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 266 307 - T 06-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CAK77_RS23685 b44767ea48c384c761cf9934c82dceec 319 Pfam PF12833 Helix-turn-helix domain 235 313 9.1E-20 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK77_RS23685 b44767ea48c384c761cf9934c82dceec 319 SUPERFAMILY SSF52317 7 193 2.59E-49 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAK77_RS23685 b44767ea48c384c761cf9934c82dceec 319 SMART SM00342 229 311 3.7E-21 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK77_RS23685 b44767ea48c384c761cf9934c82dceec 319 Gene3D G3DSA:3.40.50.880 7 217 2.5E-56 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAK77_RS07115 ed3ad4c1d575258c780aadbafcd62b48 394 Pfam PF00149 Calcineurin-like phosphoesterase 2 162 2.0E-9 T 06-07-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 CAK77_RS07115 ed3ad4c1d575258c780aadbafcd62b48 394 SUPERFAMILY SSF56300 2 296 1.41E-37 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAK77_RS07115 ed3ad4c1d575258c780aadbafcd62b48 394 PIRSF PIRSF033093 1 380 7.8E-147 T 06-07-2017 IPR014577 Uncharacterised conserved protein UCP033093, metallophosphoesterase-type CAK77_RS07115 ed3ad4c1d575258c780aadbafcd62b48 394 Gene3D G3DSA:3.60.21.10 1 243 1.3E-38 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAK77_RS13855 4403073e7be1858250d82db9a6394ea3 406 Pfam PF00144 Beta-lactamase 15 375 4.9E-64 T 06-07-2017 IPR001466 Beta-lactamase-related CAK77_RS13855 4403073e7be1858250d82db9a6394ea3 406 SUPERFAMILY SSF56601 6 379 2.82E-86 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK77_RS13855 4403073e7be1858250d82db9a6394ea3 406 Gene3D G3DSA:3.40.710.10 15 376 5.5E-79 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK77_RS02990 1da202343747af6701d54cc0ec78821b 257 SMART SM00382 28 210 5.4E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS02990 1da202343747af6701d54cc0ec78821b 257 SUPERFAMILY SSF52540 6 222 1.74E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS02990 1da202343747af6701d54cc0ec78821b 257 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK77_RS02990 1da202343747af6701d54cc0ec78821b 257 Pfam PF00005 ABC transporter 21 160 2.6E-22 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK77_RS02990 1da202343747af6701d54cc0ec78821b 257 Gene3D G3DSA:3.40.50.300 6 226 7.6E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS22845 1e1646dc660806d0e2785e7c991ce27c 427 TIGRFAM TIGR00889 2A0110: nucleoside transporter 1 411 1.9E-149 T 06-07-2017 IPR004740 Nucleoside:H+ symporter GO:0005337|GO:0015858|GO:0016021 CAK77_RS22845 1e1646dc660806d0e2785e7c991ce27c 427 Pfam PF03825 Nucleoside H+ symporter 1 411 2.4E-132 T 06-07-2017 CAK77_RS22845 1e1646dc660806d0e2785e7c991ce27c 427 Gene3D G3DSA:1.20.1250.20 207 420 6.4E-25 T 06-07-2017 CAK77_RS22845 1e1646dc660806d0e2785e7c991ce27c 427 Gene3D G3DSA:1.20.1250.20 7 185 7.1E-12 T 06-07-2017 CAK77_RS22845 1e1646dc660806d0e2785e7c991ce27c 427 SUPERFAMILY SSF103473 6 414 8.02E-35 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK77_RS01275 4a35b0ff80fd2f15aab6fb3b0ef1d5f2 183 SUPERFAMILY SSF55729 11 165 2.28E-21 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS01275 4a35b0ff80fd2f15aab6fb3b0ef1d5f2 183 Gene3D G3DSA:3.40.630.30 7 164 3.0E-25 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS01275 4a35b0ff80fd2f15aab6fb3b0ef1d5f2 183 Pfam PF13302 Acetyltransferase (GNAT) domain 13 158 8.7E-19 T 06-07-2017 IPR000182 GNAT domain GO:0008080 CAK77_RS03650 bb701da7e3dc7c15f55d5c32113daa5c 761 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 1 761 310.402 T 06-07-2017 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CAK77_RS03650 bb701da7e3dc7c15f55d5c32113daa5c 761 Pfam PF00586 AIR synthase related protein, N-terminal domain 100 201 3.1E-23 T 06-07-2017 IPR016188 PurM-like, N-terminal domain CAK77_RS03650 bb701da7e3dc7c15f55d5c32113daa5c 761 Pfam PF00586 AIR synthase related protein, N-terminal domain 477 581 4.0E-23 T 06-07-2017 IPR016188 PurM-like, N-terminal domain CAK77_RS03650 bb701da7e3dc7c15f55d5c32113daa5c 761 SUPERFAMILY SSF55326 418 588 1.96E-55 T 06-07-2017 CAK77_RS03650 bb701da7e3dc7c15f55d5c32113daa5c 761 Pfam PF02769 AIR synthase related protein, C-terminal domain 215 375 1.9E-34 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain CAK77_RS03650 bb701da7e3dc7c15f55d5c32113daa5c 761 Pfam PF02769 AIR synthase related protein, C-terminal domain 595 733 6.0E-21 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain CAK77_RS03650 bb701da7e3dc7c15f55d5c32113daa5c 761 SUPERFAMILY SSF55326 21 207 7.63E-49 T 06-07-2017 CAK77_RS03650 bb701da7e3dc7c15f55d5c32113daa5c 761 PIRSF PIRSF001587 9 761 2.9E-280 T 06-07-2017 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CAK77_RS03650 bb701da7e3dc7c15f55d5c32113daa5c 761 SUPERFAMILY SSF56042 595 760 1.5E-36 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain CAK77_RS03650 bb701da7e3dc7c15f55d5c32113daa5c 761 SUPERFAMILY SSF56042 214 448 1.79E-53 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain CAK77_RS03650 bb701da7e3dc7c15f55d5c32113daa5c 761 Gene3D G3DSA:3.30.1330.10 58 206 2.4E-50 T 06-07-2017 IPR016188 PurM-like, N-terminal domain CAK77_RS03650 bb701da7e3dc7c15f55d5c32113daa5c 761 Gene3D G3DSA:3.30.1330.10 437 585 2.0E-52 T 06-07-2017 IPR016188 PurM-like, N-terminal domain CAK77_RS03650 bb701da7e3dc7c15f55d5c32113daa5c 761 Gene3D G3DSA:3.90.650.10 268 371 9.2E-5 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain CAK77_RS03650 bb701da7e3dc7c15f55d5c32113daa5c 761 TIGRFAM TIGR01736 FGAM_synth_II: phosphoribosylformylglycinamidine synthase II 26 757 2.5E-253 T 06-07-2017 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CAK77_RS03250 4eb767036bd6e9a501c13a3f80f0da46 1034 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 783 936 3.0E-9 T 06-07-2017 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain CAK77_RS03250 4eb767036bd6e9a501c13a3f80f0da46 1034 SUPERFAMILY SSF52540 782 1018 7.68E-27 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS03250 4eb767036bd6e9a501c13a3f80f0da46 1034 Gene3D G3DSA:3.40.50.300 783 1013 2.0E-25 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS16580 d9d91115fcde7f6e1abb7e7c39a0ff6f 343 Gene3D G3DSA:3.40.50.450 1 213 2.0E-75 T 06-07-2017 CAK77_RS16580 d9d91115fcde7f6e1abb7e7c39a0ff6f 343 PIRSF PIRSF000532 1 341 2.3E-115 T 06-07-2017 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 CAK77_RS16580 d9d91115fcde7f6e1abb7e7c39a0ff6f 343 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 5 24 6.8E-75 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CAK77_RS16580 d9d91115fcde7f6e1abb7e7c39a0ff6f 343 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 94 110 6.8E-75 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CAK77_RS16580 d9d91115fcde7f6e1abb7e7c39a0ff6f 343 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 31 44 6.8E-75 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CAK77_RS16580 d9d91115fcde7f6e1abb7e7c39a0ff6f 343 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 177 194 6.8E-75 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CAK77_RS16580 d9d91115fcde7f6e1abb7e7c39a0ff6f 343 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 263 285 6.8E-75 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CAK77_RS16580 d9d91115fcde7f6e1abb7e7c39a0ff6f 343 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 159 175 6.8E-75 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CAK77_RS16580 d9d91115fcde7f6e1abb7e7c39a0ff6f 343 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 139 157 6.8E-75 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CAK77_RS16580 d9d91115fcde7f6e1abb7e7c39a0ff6f 343 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 213 225 6.8E-75 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CAK77_RS16580 d9d91115fcde7f6e1abb7e7c39a0ff6f 343 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 121 138 6.8E-75 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CAK77_RS16580 d9d91115fcde7f6e1abb7e7c39a0ff6f 343 SUPERFAMILY SSF53784 1 333 4.32E-124 T 06-07-2017 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CAK77_RS16580 d9d91115fcde7f6e1abb7e7c39a0ff6f 343 ProSitePatterns PS00433 Phosphofructokinase signature. 267 285 - T 06-07-2017 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CAK77_RS16580 d9d91115fcde7f6e1abb7e7c39a0ff6f 343 TIGRFAM TIGR02483 PFK_mixed: phosphofructokinase 2 323 4.1E-143 T 06-07-2017 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 CAK77_RS16580 d9d91115fcde7f6e1abb7e7c39a0ff6f 343 Pfam PF00365 Phosphofructokinase 2 298 2.9E-104 T 06-07-2017 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CAK77_RS16580 d9d91115fcde7f6e1abb7e7c39a0ff6f 343 Hamap MF_01976 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase [pfp]. 1 343 44.392 T 06-07-2017 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 CAK77_RS15950 718e8d473920aabb854a8ee710c9acdd 195 Pfam PF14514 Transcriptional regulator, TetR, C-terminal 73 194 1.5E-9 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS15950 718e8d473920aabb854a8ee710c9acdd 195 SUPERFAMILY SSF48498 72 195 5.93E-24 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS15950 718e8d473920aabb854a8ee710c9acdd 195 SUPERFAMILY SSF46689 4 73 1.69E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS15950 718e8d473920aabb854a8ee710c9acdd 195 Gene3D G3DSA:1.10.357.10 4 193 2.0E-37 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS15950 718e8d473920aabb854a8ee710c9acdd 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 6 48 4.6E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS01810 65b8569d7d8a9c3d8adf0e50795e2aa2 308 SUPERFAMILY SSF53613 6 296 6.24E-59 T 06-07-2017 IPR029056 Ribokinase-like CAK77_RS01810 65b8569d7d8a9c3d8adf0e50795e2aa2 308 Gene3D G3DSA:3.40.1190.20 7 304 4.5E-60 T 06-07-2017 IPR029056 Ribokinase-like CAK77_RS01810 65b8569d7d8a9c3d8adf0e50795e2aa2 308 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 248 261 - T 06-07-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CAK77_RS01810 65b8569d7d8a9c3d8adf0e50795e2aa2 308 Pfam PF00294 pfkB family carbohydrate kinase 8 294 2.5E-39 T 06-07-2017 IPR011611 Carbohydrate kinase PfkB CAK77_RS08930 f9166fb4fa7bf09647f60b870f52d28c 146 Gene3D G3DSA:1.10.10.10 6 78 4.6E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS08930 f9166fb4fa7bf09647f60b870f52d28c 146 SUPERFAMILY SSF46785 7 85 4.23E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS23185 af2c04e07593a60ed9c0503670ee56dd 330 Pfam PF03466 LysR substrate binding domain 101 230 2.4E-14 T 06-07-2017 IPR005119 LysR, substrate-binding CAK77_RS23185 af2c04e07593a60ed9c0503670ee56dd 330 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 52 4.0E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK77_RS23185 af2c04e07593a60ed9c0503670ee56dd 330 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 52 63 4.0E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK77_RS23185 af2c04e07593a60ed9c0503670ee56dd 330 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 42 4.0E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK77_RS23185 af2c04e07593a60ed9c0503670ee56dd 330 SUPERFAMILY SSF46785 15 100 2.01E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS23185 af2c04e07593a60ed9c0503670ee56dd 330 Gene3D G3DSA:3.40.190.10 120 187 1.1E-8 T 06-07-2017 CAK77_RS23185 af2c04e07593a60ed9c0503670ee56dd 330 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 18 74 6.8E-15 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK77_RS23185 af2c04e07593a60ed9c0503670ee56dd 330 SUPERFAMILY SSF53850 100 297 1.74E-14 T 06-07-2017 CAK77_RS23185 af2c04e07593a60ed9c0503670ee56dd 330 Gene3D G3DSA:3.40.190.10 188 231 5.1E-9 T 06-07-2017 CAK77_RS23185 af2c04e07593a60ed9c0503670ee56dd 330 Gene3D G3DSA:1.10.10.10 15 92 2.7E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS08980 d652079a2c5710fdcba9263a0fbd0863 354 Gene3D G3DSA:3.30.70.270 202 346 3.2E-31 T 06-07-2017 CAK77_RS08980 d652079a2c5710fdcba9263a0fbd0863 354 SUPERFAMILY SSF55073 205 346 1.33E-27 T 06-07-2017 IPR029787 Nucleotide cyclase CAK77_RS08980 d652079a2c5710fdcba9263a0fbd0863 354 Pfam PF00990 Diguanylate cyclase, GGDEF domain 200 347 3.7E-26 T 06-07-2017 IPR000160 GGDEF domain CAK77_RS08980 d652079a2c5710fdcba9263a0fbd0863 354 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 200 346 5.2E-28 T 06-07-2017 IPR000160 GGDEF domain CAK77_RS08980 d652079a2c5710fdcba9263a0fbd0863 354 SMART SM00267 190 353 5.3E-22 T 06-07-2017 IPR000160 GGDEF domain CAK77_RS15255 4fed729ce8b6e056864ecd19bd84d685 144 SUPERFAMILY SSF54427 8 132 5.55E-29 T 06-07-2017 IPR032710 NTF2-like domain CAK77_RS15255 4fed729ce8b6e056864ecd19bd84d685 144 Pfam PF07858 Limonene-1,2-epoxide hydrolase catalytic domain 9 129 1.2E-31 T 06-07-2017 IPR013100 Limonene-1,2-epoxide hydrolase CAK77_RS15255 4fed729ce8b6e056864ecd19bd84d685 144 Gene3D G3DSA:3.10.450.50 6 130 1.8E-35 T 06-07-2017 IPR032710 NTF2-like domain CAK77_RS21380 ec2c32d0a42e9f737f1bb37f05fe499f 352 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 15 345 6.0E-74 T 06-07-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CAK77_RS21380 ec2c32d0a42e9f737f1bb37f05fe499f 352 Gene3D G3DSA:3.20.20.70 8 346 2.1E-118 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK77_RS21380 ec2c32d0a42e9f737f1bb37f05fe499f 352 TIGRFAM TIGR01520 FruBisAldo_II_A: fructose-bisphosphate aldolase, class II 4 345 1.9E-146 T 06-07-2017 IPR006411 Fructose-bisphosphate aldolase, class II, yeast/E. coli subtype GO:0004332|GO:0006096 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 CAK77_RS21380 ec2c32d0a42e9f737f1bb37f05fe499f 352 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 91 102 - T 06-07-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CAK77_RS21380 ec2c32d0a42e9f737f1bb37f05fe499f 352 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 163 174 - T 06-07-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CAK77_RS21380 ec2c32d0a42e9f737f1bb37f05fe499f 352 SUPERFAMILY SSF51569 6 345 7.69E-95 T 06-07-2017 CAK77_RS21380 ec2c32d0a42e9f737f1bb37f05fe499f 352 Pfam PF01116 Fructose-bisphosphate aldolase class-II 14 345 1.1E-79 T 06-07-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CAK77_RS21380 ec2c32d0a42e9f737f1bb37f05fe499f 352 PIRSF PIRSF001359 11 346 4.4E-64 T 06-07-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CAK77_RS11825 d8bb6377a61bf7c069752d60c092f98b 353 SUPERFAMILY SSF50331 232 349 1.21E-15 T 06-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal CAK77_RS11825 d8bb6377a61bf7c069752d60c092f98b 353 SMART SM00382 23 207 1.1E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS11825 d8bb6377a61bf7c069752d60c092f98b 353 SUPERFAMILY SSF52540 17 231 1.33E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS11825 d8bb6377a61bf7c069752d60c092f98b 353 Pfam PF00005 ABC transporter 18 157 4.0E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK77_RS11825 d8bb6377a61bf7c069752d60c092f98b 353 Gene3D G3DSA:2.40.50.100 286 349 1.4E-13 T 06-07-2017 CAK77_RS11825 d8bb6377a61bf7c069752d60c092f98b 353 Gene3D G3DSA:3.40.50.300 18 226 3.6E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS11825 d8bb6377a61bf7c069752d60c092f98b 353 Pfam PF03459 TOBE domain 288 347 4.8E-10 T 06-07-2017 IPR005116 Transport-associated OB, type 1 CAK77_RS11825 d8bb6377a61bf7c069752d60c092f98b 353 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK77_RS07340 bc151412064dd4f83812228ff013024c 535 SUPERFAMILY SSF55073 353 531 3.3E-46 T 06-07-2017 IPR029787 Nucleotide cyclase CAK77_RS07340 bc151412064dd4f83812228ff013024c 535 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 359 529 3.6E-21 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CAK77_RS07340 bc151412064dd4f83812228ff013024c 535 Gene3D G3DSA:3.30.70.1230 358 531 6.4E-34 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CAK77_RS07340 bc151412064dd4f83812228ff013024c 535 SMART SM00044 326 516 1.8E-9 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CAK77_RS07340 bc151412064dd4f83812228ff013024c 535 SMART SM00304 278 330 2.7E-10 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAK77_RS07340 bc151412064dd4f83812228ff013024c 535 Pfam PF00672 HAMP domain 261 327 5.3E-11 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAK77_RS07340 bc151412064dd4f83812228ff013024c 535 SUPERFAMILY SSF158472 279 327 1.7E-7 T 06-07-2017 CAK77_RS22370 a05b7e9edc96ce17c82038ea18cfbd06 497 Gene3D G3DSA:3.30.565.10 412 495 4.4E-10 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS22370 a05b7e9edc96ce17c82038ea18cfbd06 497 Pfam PF13493 Domain of unknown function (DUF4118) 39 144 1.7E-12 T 06-07-2017 IPR025201 Sensor protein KdpD, transmembrane domain CAK77_RS22370 a05b7e9edc96ce17c82038ea18cfbd06 497 SUPERFAMILY SSF55781 152 292 2.62E-12 T 06-07-2017 IPR029016 GAF domain-like CAK77_RS22370 a05b7e9edc96ce17c82038ea18cfbd06 497 Gene3D G3DSA:3.30.450.40 143 286 3.3E-8 T 06-07-2017 IPR029016 GAF domain-like CAK77_RS22370 a05b7e9edc96ce17c82038ea18cfbd06 497 Pfam PF07730 Histidine kinase 307 372 1.9E-9 T 06-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CAK77_RS22370 a05b7e9edc96ce17c82038ea18cfbd06 497 SMART SM00387 405 495 1.1E-5 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS22370 a05b7e9edc96ce17c82038ea18cfbd06 497 SUPERFAMILY SSF55874 382 493 7.33E-15 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS22370 a05b7e9edc96ce17c82038ea18cfbd06 497 Gene3D G3DSA:1.20.120.620 37 135 3.7E-8 T 06-07-2017 CAK77_RS22370 a05b7e9edc96ce17c82038ea18cfbd06 497 SMART SM00065 140 293 0.005 T 06-07-2017 IPR003018 GAF domain GO:0005515 CAK77_RS22370 a05b7e9edc96ce17c82038ea18cfbd06 497 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 408 494 2.7E-5 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS15615 55dba0e68a327c6acc5dbd0437642e84 580 SUPERFAMILY SSF55681 419 490 1.36E-85 T 06-07-2017 CAK77_RS15615 55dba0e68a327c6acc5dbd0437642e84 580 SUPERFAMILY SSF55681 12 239 1.36E-85 T 06-07-2017 CAK77_RS15615 55dba0e68a327c6acc5dbd0437642e84 580 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 96 470 4.7E-35 T 06-07-2017 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK77_RS15615 55dba0e68a327c6acc5dbd0437642e84 580 Pfam PF03129 Anticodon binding domain 488 575 5.9E-16 T 06-07-2017 IPR004154 Anticodon-binding CAK77_RS15615 55dba0e68a327c6acc5dbd0437642e84 580 Gene3D G3DSA:3.90.960.10 280 393 6.7E-8 T 06-07-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CAK77_RS15615 55dba0e68a327c6acc5dbd0437642e84 580 PRINTS PR01046 Prolyl-tRNA synthetase signature 70 88 4.4E-14 T 06-07-2017 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CAK77_RS15615 55dba0e68a327c6acc5dbd0437642e84 580 PRINTS PR01046 Prolyl-tRNA synthetase signature 106 117 4.4E-14 T 06-07-2017 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CAK77_RS15615 55dba0e68a327c6acc5dbd0437642e84 580 PRINTS PR01046 Prolyl-tRNA synthetase signature 136 144 4.4E-14 T 06-07-2017 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CAK77_RS15615 55dba0e68a327c6acc5dbd0437642e84 580 PRINTS PR01046 Prolyl-tRNA synthetase signature 146 157 4.4E-14 T 06-07-2017 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CAK77_RS15615 55dba0e68a327c6acc5dbd0437642e84 580 SUPERFAMILY SSF55826 281 391 9.03E-11 T 06-07-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CAK77_RS15615 55dba0e68a327c6acc5dbd0437642e84 580 Hamap MF_01569 Proline--tRNA ligase [proS]. 3 580 36.145 T 06-07-2017 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 CAK77_RS15615 55dba0e68a327c6acc5dbd0437642e84 580 SUPERFAMILY SSF52954 476 579 9.97E-26 T 06-07-2017 IPR004154 Anticodon-binding CAK77_RS15615 55dba0e68a327c6acc5dbd0437642e84 580 Gene3D G3DSA:3.40.50.800 480 579 2.1E-22 T 06-07-2017 IPR004154 Anticodon-binding CAK77_RS15615 55dba0e68a327c6acc5dbd0437642e84 580 Pfam PF04073 Aminoacyl-tRNA editing domain 262 391 2.0E-20 T 06-07-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CAK77_RS15615 55dba0e68a327c6acc5dbd0437642e84 580 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 4 575 3.0E-165 T 06-07-2017 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CAK77_RS15615 55dba0e68a327c6acc5dbd0437642e84 580 Gene3D G3DSA:3.30.930.10 8 206 2.0E-90 T 06-07-2017 CAK77_RS15615 55dba0e68a327c6acc5dbd0437642e84 580 Gene3D G3DSA:3.30.930.10 404 479 2.0E-90 T 06-07-2017 CAK77_RS21140 a6d9678e0af0031b6d3025ed14d2052a 353 Gene3D G3DSA:3.30.9.10 177 291 1.9E-30 T 06-07-2017 CAK77_RS21140 a6d9678e0af0031b6d3025ed14d2052a 353 SUPERFAMILY SSF51905 292 342 1.23E-25 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS21140 a6d9678e0af0031b6d3025ed14d2052a 353 SUPERFAMILY SSF51905 9 201 1.23E-25 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS21140 a6d9678e0af0031b6d3025ed14d2052a 353 TIGRFAM TIGR02352 thiamin_ThiO: glycine oxidase ThiO 9 333 9.8E-93 T 06-07-2017 IPR012727 Glycine oxidase ThiO GO:0016491|GO:0050660 CAK77_RS21140 a6d9678e0af0031b6d3025ed14d2052a 353 Pfam PF01266 FAD dependent oxidoreductase 9 326 5.4E-47 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CAK77_RS21140 a6d9678e0af0031b6d3025ed14d2052a 353 SUPERFAMILY SSF54373 199 291 3.24E-17 T 06-07-2017 CAK77_RS21140 a6d9678e0af0031b6d3025ed14d2052a 353 Gene3D G3DSA:3.50.50.60 292 347 1.7E-12 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS21140 a6d9678e0af0031b6d3025ed14d2052a 353 Gene3D G3DSA:3.50.50.60 8 86 2.2E-15 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS21140 a6d9678e0af0031b6d3025ed14d2052a 353 Gene3D G3DSA:3.50.50.60 138 166 2.2E-15 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS23445 cd8d0742aa0279e3b240ad6292d39c63 161 SUPERFAMILY SSF54593 32 158 9.53E-26 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK77_RS23445 cd8d0742aa0279e3b240ad6292d39c63 161 Gene3D G3DSA:3.10.180.10 26 158 1.0E-29 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK77_RS23445 cd8d0742aa0279e3b240ad6292d39c63 161 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 34 156 3.6E-16 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CAK77_RS18610 8f0e93672d10a0c8bdcd325ff237352a 539 SUPERFAMILY SSF48592 6 133 2.5E-69 T 06-07-2017 CAK77_RS18610 8f0e93672d10a0c8bdcd325ff237352a 539 SUPERFAMILY SSF48592 404 519 2.5E-69 T 06-07-2017 CAK77_RS18610 8f0e93672d10a0c8bdcd325ff237352a 539 ProSitePatterns PS00296 Chaperonins cpn60 signature. 403 414 - T 06-07-2017 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020 CAK77_RS18610 8f0e93672d10a0c8bdcd325ff237352a 539 Hamap MF_00600 60 kDa chaperonin [groL]. 1 537 38.579 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 CAK77_RS18610 8f0e93672d10a0c8bdcd325ff237352a 539 SUPERFAMILY SSF52029 182 374 6.8E-74 T 06-07-2017 IPR027409 GroEL-like apical domain CAK77_RS18610 8f0e93672d10a0c8bdcd325ff237352a 539 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 525 4.8E-220 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 CAK77_RS18610 8f0e93672d10a0c8bdcd325ff237352a 539 Gene3D G3DSA:1.10.560.10 366 517 4.6E-38 T 06-07-2017 IPR027413 GroEL-like equatorial domain CAK77_RS18610 8f0e93672d10a0c8bdcd325ff237352a 539 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 524 1.7E-85 T 06-07-2017 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 CAK77_RS18610 8f0e93672d10a0c8bdcd325ff237352a 539 SUPERFAMILY SSF54849 136 202 3.66E-21 T 06-07-2017 CAK77_RS18610 8f0e93672d10a0c8bdcd325ff237352a 539 Gene3D G3DSA:3.50.7.10 195 365 4.1E-80 T 06-07-2017 IPR027409 GroEL-like apical domain CAK77_RS18610 8f0e93672d10a0c8bdcd325ff237352a 539 Gene3D G3DSA:1.10.560.10 5 194 7.2E-40 T 06-07-2017 IPR027413 GroEL-like equatorial domain CAK77_RS18610 8f0e93672d10a0c8bdcd325ff237352a 539 PRINTS PR00298 60kDa chaperonin signature 266 289 6.5E-68 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 CAK77_RS18610 8f0e93672d10a0c8bdcd325ff237352a 539 PRINTS PR00298 60kDa chaperonin signature 82 109 6.5E-68 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 CAK77_RS18610 8f0e93672d10a0c8bdcd325ff237352a 539 PRINTS PR00298 60kDa chaperonin signature 396 417 6.5E-68 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 CAK77_RS18610 8f0e93672d10a0c8bdcd325ff237352a 539 PRINTS PR00298 60kDa chaperonin signature 348 373 6.5E-68 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 CAK77_RS18610 8f0e93672d10a0c8bdcd325ff237352a 539 PRINTS PR00298 60kDa chaperonin signature 26 52 6.5E-68 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 CAK77_RS01500 3fc949fb18f5f53c72632fbc7177767d 617 Pfam PF13556 PucR C-terminal helix-turn-helix domain 546 604 2.3E-16 T 06-07-2017 IPR025736 PucR C-terminal helix-turn-helix domain CAK77_RS01500 3fc949fb18f5f53c72632fbc7177767d 617 SUPERFAMILY SSF55781 96 243 5.23E-19 T 06-07-2017 IPR029016 GAF domain-like CAK77_RS01500 3fc949fb18f5f53c72632fbc7177767d 617 Gene3D G3DSA:3.30.450.40 72 256 1.6E-19 T 06-07-2017 IPR029016 GAF domain-like CAK77_RS01500 3fc949fb18f5f53c72632fbc7177767d 617 SMART SM00065 95 250 2.0E-8 T 06-07-2017 IPR003018 GAF domain GO:0005515 CAK77_RS01500 3fc949fb18f5f53c72632fbc7177767d 617 Pfam PF13185 GAF domain 95 240 1.8E-8 T 06-07-2017 IPR003018 GAF domain GO:0005515 CAK77_RS05175 6db53344d7b18a606639d29c786e8d2c 146 SMART SM01116 75 146 2.7E-43 T 06-07-2017 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAK77_RS05175 6db53344d7b18a606639d29c786e8d2c 146 PIRSF PIRSF001263 1 146 5.1E-46 T 06-07-2017 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAK77_RS05175 6db53344d7b18a606639d29c786e8d2c 146 SUPERFAMILY SSF55234 81 145 1.7E-27 T 06-07-2017 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAK77_RS05175 6db53344d7b18a606639d29c786e8d2c 146 TIGRFAM TIGR00673 cynS: cyanase 7 145 3.1E-44 T 06-07-2017 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAK77_RS05175 6db53344d7b18a606639d29c786e8d2c 146 PRINTS PR01693 Cyanase signature 34 51 2.3E-25 T 06-07-2017 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAK77_RS05175 6db53344d7b18a606639d29c786e8d2c 146 PRINTS PR01693 Cyanase signature 14 29 2.3E-25 T 06-07-2017 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAK77_RS05175 6db53344d7b18a606639d29c786e8d2c 146 PRINTS PR01693 Cyanase signature 132 142 2.3E-25 T 06-07-2017 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAK77_RS05175 6db53344d7b18a606639d29c786e8d2c 146 PRINTS PR01693 Cyanase signature 83 97 2.3E-25 T 06-07-2017 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAK77_RS05175 6db53344d7b18a606639d29c786e8d2c 146 PRINTS PR01693 Cyanase signature 101 117 2.3E-25 T 06-07-2017 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAK77_RS05175 6db53344d7b18a606639d29c786e8d2c 146 Hamap MF_00535 Cyanate hydratase [cynS]. 1 146 68.273 T 06-07-2017 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAK77_RS05175 6db53344d7b18a606639d29c786e8d2c 146 SUPERFAMILY SSF47413 1 77 6.19E-15 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK77_RS05175 6db53344d7b18a606639d29c786e8d2c 146 Gene3D G3DSA:3.30.1160.10 81 145 1.1E-33 T 06-07-2017 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAK77_RS05175 6db53344d7b18a606639d29c786e8d2c 146 Gene3D G3DSA:1.10.260.40 1 78 1.0E-25 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK77_RS05175 6db53344d7b18a606639d29c786e8d2c 146 Pfam PF02560 Cyanate lyase C-terminal domain 81 145 8.8E-33 T 06-07-2017 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAK77_RS01405 8774e3745129cd8e8d817187532ce95f 409 Gene3D G3DSA:1.10.630.10 13 408 5.0E-113 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS01405 8774e3745129cd8e8d817187532ce95f 409 Pfam PF00067 Cytochrome P450 286 381 2.0E-17 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS01405 8774e3745129cd8e8d817187532ce95f 409 Pfam PF00067 Cytochrome P450 90 270 1.2E-6 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS01405 8774e3745129cd8e8d817187532ce95f 409 SUPERFAMILY SSF48264 13 408 1.44E-88 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS01405 8774e3745129cd8e8d817187532ce95f 409 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 353 362 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CAK77_RS01405 8774e3745129cd8e8d817187532ce95f 409 PRINTS PR00359 B-class P450 signature 330 345 1.1E-44 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS01405 8774e3745129cd8e8d817187532ce95f 409 PRINTS PR00359 B-class P450 signature 204 226 1.1E-44 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS01405 8774e3745129cd8e8d817187532ce95f 409 PRINTS PR00359 B-class P450 signature 360 371 1.1E-44 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS01405 8774e3745129cd8e8d817187532ce95f 409 PRINTS PR00359 B-class P450 signature 156 171 1.1E-44 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS01405 8774e3745129cd8e8d817187532ce95f 409 PRINTS PR00359 B-class P450 signature 302 329 1.1E-44 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS01405 8774e3745129cd8e8d817187532ce95f 409 PRINTS PR00359 B-class P450 signature 93 104 1.1E-44 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS01405 8774e3745129cd8e8d817187532ce95f 409 PRINTS PR00359 B-class P450 signature 285 296 1.1E-44 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS01405 8774e3745129cd8e8d817187532ce95f 409 PRINTS PR00359 B-class P450 signature 351 360 1.1E-44 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS01405 8774e3745129cd8e8d817187532ce95f 409 PRINTS PR00359 B-class P450 signature 139 155 1.1E-44 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS01405 8774e3745129cd8e8d817187532ce95f 409 PRINTS PR00385 P450 superfamily signature 250 267 8.5E-7 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS01405 8774e3745129cd8e8d817187532ce95f 409 PRINTS PR00385 P450 superfamily signature 360 371 8.5E-7 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS01405 8774e3745129cd8e8d817187532ce95f 409 PRINTS PR00385 P450 superfamily signature 351 360 8.5E-7 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS01405 8774e3745129cd8e8d817187532ce95f 409 PRINTS PR00385 P450 superfamily signature 285 296 8.5E-7 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS11075 2b8dbd42e79b3e38a275cb72aef81c90 380 Gene3D G3DSA:1.20.140.10 221 373 9.9E-5 T 06-07-2017 CAK77_RS11075 2b8dbd42e79b3e38a275cb72aef81c90 380 SUPERFAMILY SSF56645 41 228 1.11E-23 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK77_RS11075 2b8dbd42e79b3e38a275cb72aef81c90 380 Gene3D G3DSA:2.40.110.10 134 220 3.0E-13 T 06-07-2017 CAK77_RS11075 2b8dbd42e79b3e38a275cb72aef81c90 380 Gene3D G3DSA:1.10.540.10 50 105 2.2E-5 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS11075 2b8dbd42e79b3e38a275cb72aef81c90 380 SUPERFAMILY SSF47203 247 374 6.11E-6 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS10255 b484fc56308a8bc37d523afb0a4752fe 195 Pfam PF11290 Protein of unknown function (DUF3090) 6 175 1.0E-67 T 06-07-2017 IPR021441 Protein of unknown function DUF3090 CAK77_RS10255 b484fc56308a8bc37d523afb0a4752fe 195 TIGRFAM TIGR03847 TIGR03847: conserved hypothetical protein 5 179 3.9E-76 T 06-07-2017 IPR021441 Protein of unknown function DUF3090 CAK77_RS23090 35db9e0637dbddda310fcc9b5b6b9807 551 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 41 453 1.1E-67 T 06-07-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CAK77_RS23090 35db9e0637dbddda310fcc9b5b6b9807 551 Pfam PF00474 Sodium:solute symporter family 41 453 9.7E-46 T 06-07-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CAK77_RS22560 d838c3e41484a73afdbd7f3a2d6a21b6 139 SMART SM00881 13 107 4.8E-20 T 06-07-2017 IPR003781 CoA-binding GO:0048037 CAK77_RS22560 d838c3e41484a73afdbd7f3a2d6a21b6 139 Pfam PF13380 CoA binding domain 18 132 1.3E-35 T 06-07-2017 IPR003781 CoA-binding GO:0048037 CAK77_RS22560 d838c3e41484a73afdbd7f3a2d6a21b6 139 Gene3D G3DSA:3.40.50.720 5 136 4.0E-41 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS22560 d838c3e41484a73afdbd7f3a2d6a21b6 139 SUPERFAMILY SSF51735 3 136 8.0E-38 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS20360 f108df888d0afdf28d19c023c7c8f8bb 146 Pfam PF01638 HxlR-like helix-turn-helix 21 102 4.6E-17 T 06-07-2017 IPR002577 Helix-turn-helix, HxlR type CAK77_RS20360 f108df888d0afdf28d19c023c7c8f8bb 146 Gene3D G3DSA:1.10.10.10 18 101 4.3E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS20360 f108df888d0afdf28d19c023c7c8f8bb 146 SUPERFAMILY SSF46785 7 141 2.73E-33 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS05760 c9c9d9df388f39772e1beaaa068e4587 384 Gene3D G3DSA:2.60.40.420 31 129 1.1E-6 T 06-07-2017 IPR008972 Cupredoxin CAK77_RS05760 c9c9d9df388f39772e1beaaa068e4587 384 SUPERFAMILY SSF49503 32 127 2.66E-6 T 06-07-2017 IPR008972 Cupredoxin CAK77_RS05760 c9c9d9df388f39772e1beaaa068e4587 384 Pfam PF09375 Imelysin 144 375 1.6E-40 T 06-07-2017 CAK77_RS05760 c9c9d9df388f39772e1beaaa068e4587 384 Pfam PF13473 Cupredoxin-like domain 16 127 1.1E-11 T 06-07-2017 IPR028096 EfeO-type cupredoxin-like domain CAK77_RS04910 db0426da029fb3f0d5e36950336bc817 1066 SUPERFAMILY SSF82866 783 1006 4.71E-20 T 06-07-2017 CAK77_RS04910 db0426da029fb3f0d5e36950336bc817 1066 Gene3D G3DSA:1.20.1640.10 171 379 1.9E-30 T 06-07-2017 CAK77_RS04910 db0426da029fb3f0d5e36950336bc817 1066 Gene3D G3DSA:1.20.1640.10 817 1010 1.7E-19 T 06-07-2017 CAK77_RS04910 db0426da029fb3f0d5e36950336bc817 1066 Pfam PF03176 MMPL family 72 398 1.3E-84 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 CAK77_RS04910 db0426da029fb3f0d5e36950336bc817 1066 Pfam PF03176 MMPL family 669 1018 4.1E-72 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 CAK77_RS04910 db0426da029fb3f0d5e36950336bc817 1066 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 700 724 8.4E-5 T 06-07-2017 IPR023908 xxxLxxG heptad repeat CAK77_RS04910 db0426da029fb3f0d5e36950336bc817 1066 SUPERFAMILY SSF82866 166 369 7.19E-29 T 06-07-2017 CAK77_RS19240 c0e25673b9f4420f9881eda7ab1d7682 180 Pfam PF12079 Protein of unknown function (DUF3558) 19 177 1.3E-24 T 06-07-2017 IPR024520 Protein of unknown function DUF3558 CAK77_RS01475 fbcb03847825d9ef8b2291c247f4023e 176 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 5 128 3.8E-11 T 06-07-2017 IPR019587 Polyketide cyclase/dehydrase CAK77_RS01475 fbcb03847825d9ef8b2291c247f4023e 176 SUPERFAMILY SSF55961 5 127 6.32E-14 T 06-07-2017 CAK77_RS01475 fbcb03847825d9ef8b2291c247f4023e 176 Gene3D G3DSA:3.30.530.20 5 129 1.6E-10 T 06-07-2017 IPR023393 START-like domain CAK77_RS09140 155eb0f535f3e3b97f77c5c4385f0366 306 Pfam PF05090 Vitamin K-dependent gamma-carboxylase 117 275 1.4E-6 T 06-07-2017 IPR007782 Vitamin K-dependent gamma-carboxylase GO:0008488|GO:0017187 KEGG: 00130+4.1.1.90|Reactome: R-HSA-159740 CAK77_RS09140 155eb0f535f3e3b97f77c5c4385f0366 306 ProDom PD031536 MEMBRANE TRANSMEMBRANE YVAX YITN 180 275 4.0E-6 T 06-07-2017 CAK77_RS09140 155eb0f535f3e3b97f77c5c4385f0366 306 ProDom PD027642 TRANSMEMBRANE MEMBRANE YVAX YITO 84 132 1.0E-5 T 06-07-2017 CAK77_RS09140 155eb0f535f3e3b97f77c5c4385f0366 306 SMART SM00752 7 277 5.9E-16 T 06-07-2017 IPR011020 HTTM Reactome: R-HSA-159740 CAK77_RS09140 155eb0f535f3e3b97f77c5c4385f0366 306 TIGRFAM TIGR04033 export_SdpB: antimicrobial peptide system protein, SdpB family 14 275 9.3E-62 T 06-07-2017 IPR023894 Sporulation delaying protein SdpB CAK77_RS20780 ab5d1ff210191432b903b05570d64fb4 160 Gene3D G3DSA:3.10.450.50 110 156 8.9E-4 T 06-07-2017 IPR032710 NTF2-like domain CAK77_RS19865 93cb6edd46f98afe55bcbd30ccd336ad 721 Pfam PF00202 Aminotransferase class-III 296 616 1.8E-24 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAK77_RS19865 93cb6edd46f98afe55bcbd30ccd336ad 721 SUPERFAMILY SSF53383 296 679 1.65E-43 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK77_RS19865 93cb6edd46f98afe55bcbd30ccd336ad 721 Gene3D G3DSA:3.40.640.10 338 552 2.2E-31 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK77_RS19865 93cb6edd46f98afe55bcbd30ccd336ad 721 Gene3D G3DSA:3.90.1150.10 301 331 2.6E-5 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK77_RS19865 93cb6edd46f98afe55bcbd30ccd336ad 721 Gene3D G3DSA:3.90.1150.10 578 678 2.6E-5 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK77_RS06645 b19136c81de4eaccf51fb6ee01291ce2 687 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 389 411 1.6E-7 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAK77_RS06645 b19136c81de4eaccf51fb6ee01291ce2 687 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 508 532 1.6E-7 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAK77_RS06645 b19136c81de4eaccf51fb6ee01291ce2 687 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 658 677 1.6E-7 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAK77_RS06645 b19136c81de4eaccf51fb6ee01291ce2 687 SUPERFAMILY SSF51905 568 665 2.2E-19 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS06645 b19136c81de4eaccf51fb6ee01291ce2 687 SUPERFAMILY SSF51905 475 533 2.2E-19 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS06645 b19136c81de4eaccf51fb6ee01291ce2 687 SUPERFAMILY SSF51395 16 374 9.42E-105 T 06-07-2017 CAK77_RS06645 b19136c81de4eaccf51fb6ee01291ce2 687 Gene3D G3DSA:3.50.50.60 373 479 9.2E-27 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS06645 b19136c81de4eaccf51fb6ee01291ce2 687 Gene3D G3DSA:3.50.50.60 484 640 1.6E-46 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS06645 b19136c81de4eaccf51fb6ee01291ce2 687 Gene3D G3DSA:3.20.20.70 16 372 2.6E-115 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK77_RS06645 b19136c81de4eaccf51fb6ee01291ce2 687 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 472 490 2.1E-16 T 06-07-2017 CAK77_RS06645 b19136c81de4eaccf51fb6ee01291ce2 687 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 512 530 2.1E-16 T 06-07-2017 CAK77_RS06645 b19136c81de4eaccf51fb6ee01291ce2 687 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 390 409 2.1E-16 T 06-07-2017 CAK77_RS06645 b19136c81de4eaccf51fb6ee01291ce2 687 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 19 343 6.0E-72 T 06-07-2017 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 CAK77_RS06645 b19136c81de4eaccf51fb6ee01291ce2 687 SUPERFAMILY SSF51971 346 529 3.06E-44 T 06-07-2017 CAK77_RS06645 b19136c81de4eaccf51fb6ee01291ce2 687 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 388 663 1.6E-24 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS03110 00953f516a0d331cb6da53103362b002 382 Gene3D G3DSA:3.40.47.10 266 381 1.5E-54 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS03110 00953f516a0d331cb6da53103362b002 382 Gene3D G3DSA:3.40.47.10 157 193 1.5E-54 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS03110 00953f516a0d331cb6da53103362b002 382 SUPERFAMILY SSF53901 3 259 5.76E-61 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS03110 00953f516a0d331cb6da53103362b002 382 Gene3D G3DSA:3.40.47.10 4 124 2.2E-55 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS03110 00953f516a0d331cb6da53103362b002 382 Gene3D G3DSA:3.40.47.10 194 265 2.2E-55 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS03110 00953f516a0d331cb6da53103362b002 382 SUPERFAMILY SSF53901 260 381 1.97E-41 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS03110 00953f516a0d331cb6da53103362b002 382 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 380 1.0E-118 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 CAK77_RS03110 00953f516a0d331cb6da53103362b002 382 ProSitePatterns PS00737 Thiolases signature 2. 328 344 - T 06-07-2017 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CAK77_RS03110 00953f516a0d331cb6da53103362b002 382 Pfam PF00108 Thiolase, N-terminal domain 5 251 6.0E-55 T 06-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CAK77_RS03110 00953f516a0d331cb6da53103362b002 382 PIRSF PIRSF000429 1 382 7.0E-113 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 CAK77_RS03110 00953f516a0d331cb6da53103362b002 382 Pfam PF02803 Thiolase, C-terminal domain 260 381 1.4E-43 T 06-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CAK77_RS22380 517301c115f8efb32e109fb46beb601d 492 Pfam PF07690 Major Facilitator Superfamily 27 420 3.3E-29 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK77_RS22380 517301c115f8efb32e109fb46beb601d 492 SUPERFAMILY SSF103473 9 208 1.26E-53 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK77_RS22380 517301c115f8efb32e109fb46beb601d 492 SUPERFAMILY SSF103473 256 472 1.26E-53 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK77_RS22380 517301c115f8efb32e109fb46beb601d 492 Gene3D G3DSA:1.20.1250.20 276 481 5.2E-16 T 06-07-2017 CAK77_RS22380 517301c115f8efb32e109fb46beb601d 492 Gene3D G3DSA:1.20.1250.20 14 204 2.8E-20 T 06-07-2017 CAK77_RS20285 c86f1b30929618f62979a33b304974d7 256 SMART SM00855 13 197 7.8E-24 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 CAK77_RS20285 c86f1b30929618f62979a33b304974d7 256 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 16 25 - T 06-07-2017 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 CAK77_RS20285 c86f1b30929618f62979a33b304974d7 256 SUPERFAMILY SSF53254 13 230 3.3E-71 T 06-07-2017 IPR029033 Histidine phosphatase superfamily CAK77_RS20285 c86f1b30929618f62979a33b304974d7 256 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 14 214 9.8E-33 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 CAK77_RS20285 c86f1b30929618f62979a33b304974d7 256 Hamap MF_01039 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [gpmA]. 11 238 42.999 T 06-07-2017 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 CAK77_RS20285 c86f1b30929618f62979a33b304974d7 256 TIGRFAM TIGR01258 pgm_1: phosphoglycerate mutase 1 family 13 254 5.5E-114 T 06-07-2017 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 CAK77_RS20285 c86f1b30929618f62979a33b304974d7 256 Gene3D G3DSA:3.40.50.1240 13 255 3.6E-88 T 06-07-2017 IPR029033 Histidine phosphatase superfamily CAK77_RS07435 0164727554c92a44a0de0777e134932c 137 SUPERFAMILY SSF102712 2 129 3.14E-27 T 06-07-2017 CAK77_RS07435 0164727554c92a44a0de0777e134932c 137 Gene3D G3DSA:3.40.140.10 2 133 3.4E-33 T 06-07-2017 CAK77_RS07435 0164727554c92a44a0de0777e134932c 137 Pfam PF14464 Prokaryotic homologs of the JAB domain 6 118 9.1E-28 T 06-07-2017 IPR028090 JAB domain, prokaryotic CAK77_RS07435 0164727554c92a44a0de0777e134932c 137 SMART SM00232 1 131 9.0E-28 T 06-07-2017 IPR000555 JAB1/MPN/MOV34 metalloenzyme domain GO:0005515 CAK77_RS11270 fd76d34142f4e73ea3907b8321c7a737 496 Gene3D G3DSA:3.40.50.980 13 161 2.4E-21 T 06-07-2017 CAK77_RS11270 fd76d34142f4e73ea3907b8321c7a737 496 SUPERFAMILY SSF56801 14 489 2.49E-100 T 06-07-2017 CAK77_RS11270 fd76d34142f4e73ea3907b8321c7a737 496 Pfam PF13193 AMP-binding enzyme C-terminal domain 405 478 4.9E-10 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAK77_RS11270 fd76d34142f4e73ea3907b8321c7a737 496 Gene3D G3DSA:3.40.50.980 162 318 1.5E-27 T 06-07-2017 CAK77_RS11270 fd76d34142f4e73ea3907b8321c7a737 496 Gene3D G3DSA:2.30.38.10 319 386 3.8E-8 T 06-07-2017 CAK77_RS11270 fd76d34142f4e73ea3907b8321c7a737 496 Pfam PF00501 AMP-binding enzyme 21 396 2.8E-56 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK77_RS11270 fd76d34142f4e73ea3907b8321c7a737 496 Gene3D G3DSA:3.30.300.30 392 488 5.5E-22 T 06-07-2017 CAK77_RS14020 1d863ad1a92bdb080325c93c2a6c3233 493 Gene3D G3DSA:3.40.50.1820 9 475 5.7E-115 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS14020 1d863ad1a92bdb080325c93c2a6c3233 493 SUPERFAMILY SSF53474 10 480 1.98E-103 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS14020 1d863ad1a92bdb080325c93c2a6c3233 493 Pfam PF00135 Carboxylesterase family 9 464 7.7E-85 T 06-07-2017 IPR002018 Carboxylesterase, type B CAK77_RS14020 1d863ad1a92bdb080325c93c2a6c3233 493 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 180 195 - T 06-07-2017 IPR019826 Carboxylesterase type B, active site CAK77_RS02960 f10829db4bc2dba7721bc609b5cab4c5 158 Gene3D G3DSA:3.30.1330.50 5 156 2.0E-54 T 06-07-2017 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CAK77_RS02960 f10829db4bc2dba7721bc609b5cab4c5 158 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 6 156 4.8E-50 T 06-07-2017 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CAK77_RS02960 f10829db4bc2dba7721bc609b5cab4c5 158 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 5 157 31.326 T 06-07-2017 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CAK77_RS02960 f10829db4bc2dba7721bc609b5cab4c5 158 SUPERFAMILY SSF69765 5 156 8.63E-51 T 06-07-2017 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CAK77_RS02960 f10829db4bc2dba7721bc609b5cab4c5 158 Pfam PF02542 YgbB family 6 155 9.8E-47 T 06-07-2017 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CAK77_RS02960 f10829db4bc2dba7721bc609b5cab4c5 158 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 39 54 - T 06-07-2017 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CAK77_RS04735 5b0babb2040500f7b9abc375ad6da8c2 277 SUPERFAMILY SSF53335 17 237 2.99E-57 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS04735 5b0babb2040500f7b9abc375ad6da8c2 277 Pfam PF04072 Leucine carboxyl methyltransferase 26 180 6.5E-17 T 06-07-2017 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 CAK77_RS04735 5b0babb2040500f7b9abc375ad6da8c2 277 PIRSF PIRSF028177 6 277 6.6E-78 T 06-07-2017 IPR016874 Tetracenomycin polyketide synthesis O-methyltransferase TcmP GO:0017000|GO:1901106 CAK77_RS04735 5b0babb2040500f7b9abc375ad6da8c2 277 Gene3D G3DSA:3.40.50.150 10 243 2.2E-39 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS03385 ff329abe5a57b2a0d7aea653a7e0e1dd 333 SUPERFAMILY SSF52540 31 305 4.1E-38 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS03385 ff329abe5a57b2a0d7aea653a7e0e1dd 333 Gene3D G3DSA:1.10.8.300 213 330 5.9E-39 T 06-07-2017 CAK77_RS03385 ff329abe5a57b2a0d7aea653a7e0e1dd 333 Gene3D G3DSA:3.40.50.300 33 196 5.9E-39 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS03385 ff329abe5a57b2a0d7aea653a7e0e1dd 333 PIRSF PIRSF002849 2 333 1.1E-120 T 06-07-2017 IPR016366 ATPase chaperone, AAA-type, MoxR, predicted CAK77_RS03385 ff329abe5a57b2a0d7aea653a7e0e1dd 333 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 51 181 1.6E-60 T 06-07-2017 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 CAK77_RS03385 ff329abe5a57b2a0d7aea653a7e0e1dd 333 SMART SM00382 48 189 2.0E-5 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS04120 ccd2198cf7e980f959bc6c5cc07ff9f7 185 SMART SM00530 14 69 2.7E-14 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAK77_RS04120 ccd2198cf7e980f959bc6c5cc07ff9f7 185 Gene3D G3DSA:1.10.260.40 6 70 2.2E-18 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK77_RS04120 ccd2198cf7e980f959bc6c5cc07ff9f7 185 Pfam PF13560 Helix-turn-helix domain 11 66 1.1E-14 T 06-07-2017 CAK77_RS04120 ccd2198cf7e980f959bc6c5cc07ff9f7 185 SUPERFAMILY SSF51182 97 176 2.9E-13 T 06-07-2017 IPR011051 RmlC-like cupin domain CAK77_RS04120 ccd2198cf7e980f959bc6c5cc07ff9f7 185 Gene3D G3DSA:2.60.120.10 87 177 4.4E-19 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK77_RS04120 ccd2198cf7e980f959bc6c5cc07ff9f7 185 SUPERFAMILY SSF47413 10 71 1.15E-15 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK77_RS22915 2bdabeecb89e0bbf671d361646e79dfb 288 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 144 152 6.5E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS22915 2bdabeecb89e0bbf671d361646e79dfb 288 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 91 102 6.5E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS22915 2bdabeecb89e0bbf671d361646e79dfb 288 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 164 183 6.5E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS22915 2bdabeecb89e0bbf671d361646e79dfb 288 Pfam PF00106 short chain dehydrogenase 8 205 3.5E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS22915 2bdabeecb89e0bbf671d361646e79dfb 288 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 151 179 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK77_RS22915 2bdabeecb89e0bbf671d361646e79dfb 288 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 91 102 1.2E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS22915 2bdabeecb89e0bbf671d361646e79dfb 288 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 138 154 1.2E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS22915 2bdabeecb89e0bbf671d361646e79dfb 288 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 185 202 1.2E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS22915 2bdabeecb89e0bbf671d361646e79dfb 288 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 183 1.2E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS22915 2bdabeecb89e0bbf671d361646e79dfb 288 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.2E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS22915 2bdabeecb89e0bbf671d361646e79dfb 288 SUPERFAMILY SSF51735 1 245 1.25E-58 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS22915 2bdabeecb89e0bbf671d361646e79dfb 288 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 198 5.9E-4 T 06-07-2017 CAK77_RS22915 2bdabeecb89e0bbf671d361646e79dfb 288 Gene3D G3DSA:3.40.50.720 4 245 1.7E-59 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS02740 7f58d27b499258b2bef0a85b9364e7b9 343 Gene3D G3DSA:3.90.180.10 1 169 1.5E-30 T 06-07-2017 IPR011032 GroES-like CAK77_RS02740 7f58d27b499258b2bef0a85b9364e7b9 343 SUPERFAMILY SSF50129 1 177 9.74E-32 T 06-07-2017 IPR011032 GroES-like CAK77_RS02740 7f58d27b499258b2bef0a85b9364e7b9 343 SUPERFAMILY SSF51735 141 309 1.8E-28 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS02740 7f58d27b499258b2bef0a85b9364e7b9 343 Pfam PF00107 Zinc-binding dehydrogenase 178 304 1.2E-16 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAK77_RS02740 7f58d27b499258b2bef0a85b9364e7b9 343 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 104 2.0E-11 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAK77_RS02740 7f58d27b499258b2bef0a85b9364e7b9 343 Gene3D G3DSA:3.40.50.720 170 288 5.6E-30 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS05580 9102be7401113c1f2ee46b5152ff27b8 301 SUPERFAMILY SSF88659 94 169 1.87E-12 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS05580 9102be7401113c1f2ee46b5152ff27b8 301 Gene3D G3DSA:1.10.1740.10 7 76 1.3E-10 T 06-07-2017 CAK77_RS05580 9102be7401113c1f2ee46b5152ff27b8 301 Pfam PF04542 Sigma-70 region 2 9 75 4.7E-11 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS05580 9102be7401113c1f2ee46b5152ff27b8 301 Gene3D G3DSA:3.10.450.50 172 291 1.3E-13 T 06-07-2017 IPR032710 NTF2-like domain CAK77_RS05580 9102be7401113c1f2ee46b5152ff27b8 301 SUPERFAMILY SSF54427 175 293 4.75E-15 T 06-07-2017 IPR032710 NTF2-like domain CAK77_RS05580 9102be7401113c1f2ee46b5152ff27b8 301 TIGRFAM TIGR02957 SigX4: RNA polymerase sigma-70 factor, TIGR02957 family 8 292 5.1E-102 T 06-07-2017 IPR014303 RNA polymerase sigma-70, ECF type CAK77_RS05580 9102be7401113c1f2ee46b5152ff27b8 301 SUPERFAMILY SSF88946 7 87 1.26E-10 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS05580 9102be7401113c1f2ee46b5152ff27b8 301 Pfam PF08281 Sigma-70, region 4 112 162 2.0E-14 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS05580 9102be7401113c1f2ee46b5152ff27b8 301 Gene3D G3DSA:1.10.10.10 108 165 4.4E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS05580 9102be7401113c1f2ee46b5152ff27b8 301 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 7 165 2.4E-18 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS10395 64c680c1276190baf871578d33142eff 247 Gene3D G3DSA:3.40.30.10 102 184 9.5E-7 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK77_RS10395 64c680c1276190baf871578d33142eff 247 ProSitePatterns PS01099 Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. 138 156 - T 06-07-2017 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS10395 64c680c1276190baf871578d33142eff 247 SUPERFAMILY SSF52833 37 189 7.83E-45 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK77_RS10395 64c680c1276190baf871578d33142eff 247 PIRSF PIRSF000216 15 239 1.7E-70 T 06-07-2017 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS10395 64c680c1276190baf871578d33142eff 247 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 38 180 4.9E-46 T 06-07-2017 CAK77_RS14775 b354bca61db7191884b1890ff0cd073b 340 SUPERFAMILY SSF51735 1 320 2.7E-55 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS14775 b354bca61db7191884b1890ff0cd073b 340 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1 162 0.0014 T 06-07-2017 CAK77_RS14775 b354bca61db7191884b1890ff0cd073b 340 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 180 7.9E-23 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 CAK77_RS14775 b354bca61db7191884b1890ff0cd073b 340 Gene3D G3DSA:3.40.50.720 1 320 6.6E-50 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS11520 052823f427c3592e819d96a3bd9bead6 315 SUPERFAMILY SSF47823 11 107 6.28E-15 T 06-07-2017 IPR010998 Integrase, Lambda-type, N-terminal CAK77_RS11520 052823f427c3592e819d96a3bd9bead6 315 Pfam PF00589 Phage integrase family 124 298 3.4E-47 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAK77_RS11520 052823f427c3592e819d96a3bd9bead6 315 SUPERFAMILY SSF56349 119 311 8.83E-54 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CAK77_RS11520 052823f427c3592e819d96a3bd9bead6 315 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 12 101 9.0E-23 T 06-07-2017 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CAK77_RS11520 052823f427c3592e819d96a3bd9bead6 315 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 10 314 54.006 T 06-07-2017 IPR023009 Tyrosine recombinase XerC/XerD CAK77_RS11520 052823f427c3592e819d96a3bd9bead6 315 Gene3D G3DSA:1.10.443.10 124 306 1.8E-56 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAK77_RS11520 052823f427c3592e819d96a3bd9bead6 315 Hamap MF_01807 Tyrosine recombinase XerD [xerD]. 8 314 57.266 T 06-07-2017 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 CAK77_RS11520 052823f427c3592e819d96a3bd9bead6 315 TIGRFAM TIGR02225 recomb_XerD: tyrosine recombinase XerD 13 314 2.4E-104 T 06-07-2017 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 CAK77_RS11520 052823f427c3592e819d96a3bd9bead6 315 Gene3D G3DSA:1.10.150.130 11 112 4.7E-24 T 06-07-2017 IPR023109 Integrase/recombinase, N-terminal CAK77_RS08900 901bc9b85ef6bfa6c64ffbc0c4cc2e57 379 Gene3D G3DSA:1.20.140.10 217 372 7.5E-40 T 06-07-2017 CAK77_RS08900 901bc9b85ef6bfa6c64ffbc0c4cc2e57 379 Gene3D G3DSA:2.40.110.10 122 216 3.5E-40 T 06-07-2017 CAK77_RS08900 901bc9b85ef6bfa6c64ffbc0c4cc2e57 379 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 216 9.9E-26 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAK77_RS08900 901bc9b85ef6bfa6c64ffbc0c4cc2e57 379 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 228 373 8.6E-30 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS08900 901bc9b85ef6bfa6c64ffbc0c4cc2e57 379 SUPERFAMILY SSF56645 2 238 1.83E-81 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK77_RS08900 901bc9b85ef6bfa6c64ffbc0c4cc2e57 379 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 335 354 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CAK77_RS08900 901bc9b85ef6bfa6c64ffbc0c4cc2e57 379 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 5 118 1.2E-28 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS08900 901bc9b85ef6bfa6c64ffbc0c4cc2e57 379 Gene3D G3DSA:1.10.540.10 2 119 3.5E-34 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS08900 901bc9b85ef6bfa6c64ffbc0c4cc2e57 379 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 124 136 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CAK77_RS08900 901bc9b85ef6bfa6c64ffbc0c4cc2e57 379 SUPERFAMILY SSF47203 228 373 7.73E-31 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS06575 10d0e3536160d9656aad182426c5098f 633 SMART SM00849 102 324 3.1E-24 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK77_RS06575 10d0e3536160d9656aad182426c5098f 633 Gene3D G3DSA:3.60.15.10 88 188 4.6E-39 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK77_RS06575 10d0e3536160d9656aad182426c5098f 633 Gene3D G3DSA:3.60.15.10 230 354 4.6E-39 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK77_RS06575 10d0e3536160d9656aad182426c5098f 633 Pfam PF14864 Alkyl sulfatase C-terminal 508 633 1.7E-36 T 06-07-2017 IPR029229 Alkyl sulfatase, C-terminal CAK77_RS06575 10d0e3536160d9656aad182426c5098f 633 Pfam PF14863 Alkyl sulfatase dimerisation 363 499 8.0E-63 T 06-07-2017 IPR029228 Alkyl sulfatase dimerisation domain GO:0046983 CAK77_RS06575 10d0e3536160d9656aad182426c5098f 633 SUPERFAMILY SSF56281 5 501 1.36E-149 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK77_RS06575 10d0e3536160d9656aad182426c5098f 633 SUPERFAMILY SSF55718 509 633 3.83E-27 T 06-07-2017 IPR003033 SCP2 sterol-binding domain CAK77_RS06575 10d0e3536160d9656aad182426c5098f 633 Pfam PF00753 Metallo-beta-lactamase superfamily 98 324 2.9E-36 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK77_RS06575 10d0e3536160d9656aad182426c5098f 633 Gene3D G3DSA:3.30.1050.10 513 622 5.1E-4 T 06-07-2017 IPR003033 SCP2 sterol-binding domain CAK77_RS05235 ba60d3bb92cd4c36014f2e09baa77f17 249 SUPERFAMILY SSF51735 4 246 2.7E-51 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS05235 ba60d3bb92cd4c36014f2e09baa77f17 249 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK77_RS05235 ba60d3bb92cd4c36014f2e09baa77f17 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 6.9E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS05235 ba60d3bb92cd4c36014f2e09baa77f17 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 6.9E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS05235 ba60d3bb92cd4c36014f2e09baa77f17 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 6.9E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS05235 ba60d3bb92cd4c36014f2e09baa77f17 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 6.9E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS05235 ba60d3bb92cd4c36014f2e09baa77f17 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 6.9E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS05235 ba60d3bb92cd4c36014f2e09baa77f17 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 4.8E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS05235 ba60d3bb92cd4c36014f2e09baa77f17 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 4.8E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS05235 ba60d3bb92cd4c36014f2e09baa77f17 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 4.8E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS05235 ba60d3bb92cd4c36014f2e09baa77f17 249 Gene3D G3DSA:3.40.50.720 6 204 8.8E-50 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS05235 ba60d3bb92cd4c36014f2e09baa77f17 249 Pfam PF00106 short chain dehydrogenase 5 196 5.6E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS20310 a6729a9a6fad1ffeaa38022a57beeb0f 184 Gene3D G3DSA:2.30.110.10 5 132 2.6E-14 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS20310 a6729a9a6fad1ffeaa38022a57beeb0f 184 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 8 100 1.5E-9 T 06-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAK77_RS20310 a6729a9a6fad1ffeaa38022a57beeb0f 184 SUPERFAMILY SSF50475 7 132 4.28E-10 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS10290 c8c8bcd42121dcdcf65026bf730d08c3 293 Pfam PF00106 short chain dehydrogenase 11 199 1.8E-48 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS10290 c8c8bcd42121dcdcf65026bf730d08c3 293 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 11 191 2.7E-5 T 06-07-2017 CAK77_RS10290 c8c8bcd42121dcdcf65026bf730d08c3 293 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 7.4E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS10290 c8c8bcd42121dcdcf65026bf730d08c3 293 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 7.4E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS10290 c8c8bcd42121dcdcf65026bf730d08c3 293 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 7.4E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS10290 c8c8bcd42121dcdcf65026bf730d08c3 293 Gene3D G3DSA:3.40.50.720 9 239 3.0E-61 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS10290 c8c8bcd42121dcdcf65026bf730d08c3 293 SUPERFAMILY SSF51735 8 260 1.52E-62 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS10290 c8c8bcd42121dcdcf65026bf730d08c3 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 6.2E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS10290 c8c8bcd42121dcdcf65026bf730d08c3 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 6.2E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS10290 c8c8bcd42121dcdcf65026bf730d08c3 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 6.2E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS10290 c8c8bcd42121dcdcf65026bf730d08c3 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 6.2E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS10290 c8c8bcd42121dcdcf65026bf730d08c3 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 6.2E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS10290 c8c8bcd42121dcdcf65026bf730d08c3 293 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK77_RS06445 5b219632406acf7c16b54dc3f25ead4b 112 Gene3D G3DSA:1.10.287.1060 11 100 3.2E-5 T 06-07-2017 CAK77_RS06445 5b219632406acf7c16b54dc3f25ead4b 112 Pfam PF06013 Proteins of 100 residues with WXG 13 97 1.4E-6 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like CAK77_RS06445 5b219632406acf7c16b54dc3f25ead4b 112 SUPERFAMILY SSF140453 12 103 3.01E-8 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like CAK77_RS03075 b956cc6714e692b6d9015f9072cf432d 317 SUPERFAMILY SSF56645 6 131 1.37E-14 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK77_RS03075 b956cc6714e692b6d9015f9072cf432d 317 Gene3D G3DSA:1.10.540.10 4 95 2.7E-12 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS03075 b956cc6714e692b6d9015f9072cf432d 317 Gene3D G3DSA:1.20.140.10 182 303 1.1E-26 T 06-07-2017 CAK77_RS03075 b956cc6714e692b6d9015f9072cf432d 317 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 187 303 2.2E-20 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS03075 b956cc6714e692b6d9015f9072cf432d 317 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 91 4.0E-12 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS03075 b956cc6714e692b6d9015f9072cf432d 317 SUPERFAMILY SSF47203 182 304 4.79E-30 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS22580 0943467ff023eec586431df6addc6fbe 332 PRINTS PR01217 Proline rich extensin signature 74 90 3.6E-9 T 06-07-2017 CAK77_RS22580 0943467ff023eec586431df6addc6fbe 332 PRINTS PR01217 Proline rich extensin signature 37 49 3.6E-9 T 06-07-2017 CAK77_RS22580 0943467ff023eec586431df6addc6fbe 332 PRINTS PR01217 Proline rich extensin signature 53 74 3.6E-9 T 06-07-2017 CAK77_RS22580 0943467ff023eec586431df6addc6fbe 332 PRINTS PR01217 Proline rich extensin signature 134 146 3.6E-9 T 06-07-2017 CAK77_RS22580 0943467ff023eec586431df6addc6fbe 332 SUPERFAMILY SSF141523 189 312 3.53E-28 T 06-07-2017 CAK77_RS22580 0943467ff023eec586431df6addc6fbe 332 Pfam PF03734 L,D-transpeptidase catalytic domain 189 312 2.1E-19 T 06-07-2017 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 CAK77_RS22580 0943467ff023eec586431df6addc6fbe 332 Gene3D G3DSA:2.40.440.10 190 313 4.9E-20 T 06-07-2017 CAK77_RS00820 0d7b027c7f69d38d7f365cfc61180c88 261 SUPERFAMILY SSF50475 5 254 4.71E-30 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS00820 0d7b027c7f69d38d7f365cfc61180c88 261 Gene3D G3DSA:3.20.180.10 166 248 5.4E-12 T 06-07-2017 IPR019595 Domain of unknown function DUF2470 CAK77_RS00820 0d7b027c7f69d38d7f365cfc61180c88 261 Pfam PF10615 Protein of unknown function (DUF2470) 172 244 1.3E-10 T 06-07-2017 IPR019595 Domain of unknown function DUF2470 CAK77_RS00905 52be4b77007f1028f8260f765a1d89fc 346 SUPERFAMILY SSF140459 8 177 2.88E-30 T 06-07-2017 CAK77_RS00905 52be4b77007f1028f8260f765a1d89fc 346 Pfam PF00823 PPE family 21 164 1.8E-18 T 06-07-2017 IPR000030 PPE family CAK77_RS17850 488cc4ac399066200cc100ef655d418b 228 SMART SM00862 149 225 2.6E-24 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAK77_RS17850 488cc4ac399066200cc100ef655d418b 228 Gene3D G3DSA:3.40.50.2300 4 125 3.9E-41 T 06-07-2017 CAK77_RS17850 488cc4ac399066200cc100ef655d418b 228 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 224 8.2E-26 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAK77_RS17850 488cc4ac399066200cc100ef655d418b 228 Pfam PF00072 Response regulator receiver domain 8 117 4.4E-30 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK77_RS17850 488cc4ac399066200cc100ef655d418b 228 Gene3D G3DSA:1.10.10.10 128 225 1.0E-32 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS17850 488cc4ac399066200cc100ef655d418b 228 SMART SM00448 6 116 2.0E-46 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK77_RS17850 488cc4ac399066200cc100ef655d418b 228 SUPERFAMILY SSF52172 6 182 4.13E-44 T 06-07-2017 IPR011006 CheY-like superfamily CAK77_RS23155 205180d689410e99c46464f9ca5c5228 185 Pfam PF04542 Sigma-70 region 2 30 93 1.4E-8 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS23155 205180d689410e99c46464f9ca5c5228 185 Pfam PF08281 Sigma-70, region 4 127 174 1.2E-9 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS23155 205180d689410e99c46464f9ca5c5228 185 SUPERFAMILY SSF88946 24 113 1.92E-10 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS23155 205180d689410e99c46464f9ca5c5228 185 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 28 174 4.9E-15 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS23155 205180d689410e99c46464f9ca5c5228 185 Gene3D G3DSA:1.10.10.10 127 175 4.5E-9 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS23155 205180d689410e99c46464f9ca5c5228 185 SUPERFAMILY SSF88659 125 174 6.35E-9 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS23155 205180d689410e99c46464f9ca5c5228 185 Gene3D G3DSA:1.10.1740.10 24 117 1.7E-11 T 06-07-2017 CAK77_RS10775 a2d229b798fe985375c3784199002fe4 132 Pfam PF05423 Mycobacterium membrane protein 2 131 4.6E-26 T 06-07-2017 IPR008693 Transport accessory protein MmpS CAK77_RS04840 ee41d57a51a924f1424bdb774d61c252 212 Gene3D G3DSA:1.10.357.10 62 206 1.9E-41 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS04840 ee41d57a51a924f1424bdb774d61c252 212 SUPERFAMILY SSF48498 91 206 1.88E-32 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS04840 ee41d57a51a924f1424bdb774d61c252 212 SUPERFAMILY SSF46689 10 81 6.31E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS04840 ee41d57a51a924f1424bdb774d61c252 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 1.3E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS04840 ee41d57a51a924f1424bdb774d61c252 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 1.3E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS04840 ee41d57a51a924f1424bdb774d61c252 212 Gene3D G3DSA:1.10.10.60 17 61 4.7E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS04840 ee41d57a51a924f1424bdb774d61c252 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 67 1.6E-13 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS22500 720d7b3e90b1dfab82bc6a138a8d040b 391 SUPERFAMILY SSF55874 270 385 6.16E-11 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS22500 720d7b3e90b1dfab82bc6a138a8d040b 391 Gene3D G3DSA:3.30.565.10 262 387 1.6E-9 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS22500 720d7b3e90b1dfab82bc6a138a8d040b 391 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 293 386 4.6E-5 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS24015 a64efaa4231ee957f0659b8bd061892e 291 Pfam PF00296 Luciferase-like monooxygenase 21 238 1.4E-40 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS24015 a64efaa4231ee957f0659b8bd061892e 291 SUPERFAMILY SSF51679 18 288 9.27E-54 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS24015 a64efaa4231ee957f0659b8bd061892e 291 TIGRFAM TIGR03560 F420_Rv1855c: probable F420-dependent oxidoreductase, Rv1855c family 14 232 4.6E-88 T 06-07-2017 IPR019952 F420-dependent oxidoreductase-predicted, Rv1855c CAK77_RS24015 a64efaa4231ee957f0659b8bd061892e 291 Gene3D G3DSA:3.20.20.30 19 235 1.0E-58 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS19095 51f91b5db632890a6fa3ffdca8477d06 500 SUPERFAMILY SSF53901 31 128 2.64E-6 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS19095 51f91b5db632890a6fa3ffdca8477d06 500 SUPERFAMILY SSF53901 238 264 2.64E-6 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS19095 51f91b5db632890a6fa3ffdca8477d06 500 Gene3D G3DSA:3.40.47.10 32 137 4.1E-5 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS19095 51f91b5db632890a6fa3ffdca8477d06 500 Gene3D G3DSA:3.40.47.10 301 390 2.2E-5 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS19095 51f91b5db632890a6fa3ffdca8477d06 500 SUPERFAMILY SSF53901 286 401 8.93E-20 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS11705 39f9c24f84c9ec881aaa48930c589045 453 Pfam PF01595 Domain of unknown function DUF21 11 202 6.3E-34 T 06-07-2017 IPR002550 Domain of unknown function DUF21 CAK77_RS11705 39f9c24f84c9ec881aaa48930c589045 453 Pfam PF03471 Transporter associated domain 354 440 2.2E-21 T 06-07-2017 IPR005170 Transporter-associated domain CAK77_RS11705 39f9c24f84c9ec881aaa48930c589045 453 SUPERFAMILY SSF54631 208 347 2.78E-25 T 06-07-2017 CAK77_RS11705 39f9c24f84c9ec881aaa48930c589045 453 Gene3D G3DSA:3.30.465.10 333 440 1.7E-25 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAK77_RS11705 39f9c24f84c9ec881aaa48930c589045 453 Gene3D G3DSA:3.10.580.10 208 332 6.0E-17 T 06-07-2017 CAK77_RS11705 39f9c24f84c9ec881aaa48930c589045 453 SMART SM01091 352 442 1.4E-23 T 06-07-2017 IPR005170 Transporter-associated domain CAK77_RS11705 39f9c24f84c9ec881aaa48930c589045 453 SUPERFAMILY SSF56176 354 450 1.09E-19 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAK77_RS11705 39f9c24f84c9ec881aaa48930c589045 453 Pfam PF00571 CBS domain 219 273 0.0029 T 06-07-2017 IPR000644 CBS domain CAK77_RS11705 39f9c24f84c9ec881aaa48930c589045 453 Pfam PF00571 CBS domain 289 338 7.6E-4 T 06-07-2017 IPR000644 CBS domain CAK77_RS12205 5446e720534467001a1696814bf1a821 231 Pfam PF05175 Methyltransferase small domain 25 116 1.5E-12 T 06-07-2017 IPR007848 Methyltransferase small domain GO:0008168 CAK77_RS12205 5446e720534467001a1696814bf1a821 231 SUPERFAMILY SSF53335 6 186 4.99E-33 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS12205 5446e720534467001a1696814bf1a821 231 Gene3D G3DSA:3.40.50.150 10 197 2.1E-35 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS12205 5446e720534467001a1696814bf1a821 231 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 107 113 - T 06-07-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CAK77_RS12205 5446e720534467001a1696814bf1a821 231 TIGRFAM TIGR00537 hemK_rel_arch: putative methylase 17 202 1.0E-25 T 06-07-2017 IPR004557 Eukaryotic/archaeal PrmC-related GO:0008276 Reactome: R-HSA-156581|Reactome: R-HSA-72764 CAK77_RS05415 0cbf29893c56223fd8c6095ea9cf48bb 437 Gene3D G3DSA:2.30.42.10 351 435 1.2E-17 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAK77_RS05415 0cbf29893c56223fd8c6095ea9cf48bb 437 Gene3D G3DSA:2.40.10.10 130 217 1.7E-24 T 06-07-2017 CAK77_RS05415 0cbf29893c56223fd8c6095ea9cf48bb 437 Pfam PF13180 PDZ domain 350 432 2.5E-16 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAK77_RS05415 0cbf29893c56223fd8c6095ea9cf48bb 437 Gene3D G3DSA:2.40.10.10 224 350 2.6E-43 T 06-07-2017 CAK77_RS05415 0cbf29893c56223fd8c6095ea9cf48bb 437 Pfam PF13365 Trypsin-like peptidase domain 157 302 9.3E-32 T 06-07-2017 CAK77_RS05415 0cbf29893c56223fd8c6095ea9cf48bb 437 SUPERFAMILY SSF50156 331 431 1.08E-16 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAK77_RS05415 0cbf29893c56223fd8c6095ea9cf48bb 437 PRINTS PR00834 HtrA/DegQ protease family signature 232 256 2.7E-41 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAK77_RS05415 0cbf29893c56223fd8c6095ea9cf48bb 437 PRINTS PR00834 HtrA/DegQ protease family signature 379 391 2.7E-41 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAK77_RS05415 0cbf29893c56223fd8c6095ea9cf48bb 437 PRINTS PR00834 HtrA/DegQ protease family signature 273 290 2.7E-41 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAK77_RS05415 0cbf29893c56223fd8c6095ea9cf48bb 437 PRINTS PR00834 HtrA/DegQ protease family signature 295 312 2.7E-41 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAK77_RS05415 0cbf29893c56223fd8c6095ea9cf48bb 437 PRINTS PR00834 HtrA/DegQ protease family signature 166 178 2.7E-41 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAK77_RS05415 0cbf29893c56223fd8c6095ea9cf48bb 437 PRINTS PR00834 HtrA/DegQ protease family signature 191 211 2.7E-41 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAK77_RS05415 0cbf29893c56223fd8c6095ea9cf48bb 437 SUPERFAMILY SSF50494 132 345 1.7E-54 T 06-07-2017 IPR009003 Peptidase S1, PA clan CAK77_RS05415 0cbf29893c56223fd8c6095ea9cf48bb 437 SMART SM00228 349 421 9.7E-9 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAK77_RS16445 023534d7ac60443e9608717a12101ef4 407 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 133 344 1.4E-33 T 06-07-2017 IPR018713 Domain of unknown function DUF2236 CAK77_RS24340 970702ce42aa7ce9e9f47556cbcfe7b2 308 Gene3D G3DSA:3.60.15.10 8 296 1.7E-37 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK77_RS24340 970702ce42aa7ce9e9f47556cbcfe7b2 308 Pfam PF00753 Metallo-beta-lactamase superfamily 67 283 1.5E-15 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK77_RS24340 970702ce42aa7ce9e9f47556cbcfe7b2 308 SUPERFAMILY SSF56281 65 291 1.17E-32 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK77_RS24340 970702ce42aa7ce9e9f47556cbcfe7b2 308 SMART SM00849 63 283 3.0E-16 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK77_RS11370 cbf1e6170ff75358bf9b9274f9ecd6fe 347 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 148 164 - T 06-07-2017 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CAK77_RS11370 cbf1e6170ff75358bf9b9274f9ecd6fe 347 SUPERFAMILY SSF55347 153 315 1.27E-47 T 06-07-2017 CAK77_RS11370 cbf1e6170ff75358bf9b9274f9ecd6fe 347 SUPERFAMILY SSF51735 5 178 3.56E-40 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS11370 cbf1e6170ff75358bf9b9274f9ecd6fe 347 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 7 135 6.6E-21 T 06-07-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CAK77_RS11370 cbf1e6170ff75358bf9b9274f9ecd6fe 347 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 5 341 38.112 T 06-07-2017 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CAK77_RS11370 cbf1e6170ff75358bf9b9274f9ecd6fe 347 Gene3D G3DSA:3.40.50.720 4 161 8.1E-48 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS11370 cbf1e6170ff75358bf9b9274f9ecd6fe 347 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 162 318 5.2E-23 T 06-07-2017 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CAK77_RS11370 cbf1e6170ff75358bf9b9274f9ecd6fe 347 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 6 347 1.6E-113 T 06-07-2017 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CAK77_RS11370 cbf1e6170ff75358bf9b9274f9ecd6fe 347 Gene3D G3DSA:3.30.360.10 162 315 4.7E-57 T 06-07-2017 CAK77_RS11370 cbf1e6170ff75358bf9b9274f9ecd6fe 347 SMART SM00859 6 143 1.3E-35 T 06-07-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CAK77_RS24255 836f04ec405805c09c8e824b4bd28796 259 TIGRFAM TIGR03084 TIGR03084: TIGR03084 family protein 7 258 2.9E-112 T 06-07-2017 IPR017518 Conserved hypothetical protein CHP03084 CAK77_RS24255 836f04ec405805c09c8e824b4bd28796 259 Pfam PF08608 Wyosine base formation 184 231 5.8E-9 T 06-07-2017 IPR013917 tRNA wybutosine-synthesis MetaCyc: PWY-7285|MetaCyc: PWY-7286 CAK77_RS24255 836f04ec405805c09c8e824b4bd28796 259 SUPERFAMILY SSF109854 4 154 4.88E-37 T 06-07-2017 CAK77_RS24255 836f04ec405805c09c8e824b4bd28796 259 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 11 225 7.5E-49 T 06-07-2017 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type CAK77_RS24255 836f04ec405805c09c8e824b4bd28796 259 Gene3D G3DSA:1.20.120.450 6 134 1.7E-10 T 06-07-2017 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase CAK77_RS24255 836f04ec405805c09c8e824b4bd28796 259 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 12 148 1.6E-28 T 06-07-2017 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 CAK77_RS19680 5095979e5e376e14f6d4e4830df4edb4 409 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 298 314 6.8E-10 T 06-07-2017 CAK77_RS19680 5095979e5e376e14f6d4e4830df4edb4 409 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 151 166 6.8E-10 T 06-07-2017 CAK77_RS19680 5095979e5e376e14f6d4e4830df4edb4 409 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 283 298 6.8E-10 T 06-07-2017 CAK77_RS19680 5095979e5e376e14f6d4e4830df4edb4 409 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 6.8E-10 T 06-07-2017 CAK77_RS19680 5095979e5e376e14f6d4e4830df4edb4 409 Pfam PF01494 FAD binding domain 6 311 2.6E-12 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 CAK77_RS19680 5095979e5e376e14f6d4e4830df4edb4 409 Gene3D G3DSA:3.50.50.60 4 169 4.8E-20 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS19680 5095979e5e376e14f6d4e4830df4edb4 409 Gene3D G3DSA:3.30.9.10 170 320 3.7E-42 T 06-07-2017 CAK77_RS19680 5095979e5e376e14f6d4e4830df4edb4 409 SUPERFAMILY SSF51905 5 172 2.78E-42 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS19680 5095979e5e376e14f6d4e4830df4edb4 409 SUPERFAMILY SSF51905 279 351 2.78E-42 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS19680 5095979e5e376e14f6d4e4830df4edb4 409 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 6 317 1.8E-68 T 06-07-2017 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 CAK77_RS00095 c730267c60b0352999691be9048fa95c 306 Pfam PF08241 Methyltransferase domain 96 194 1.0E-17 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CAK77_RS00095 c730267c60b0352999691be9048fa95c 306 SUPERFAMILY SSF53335 53 266 4.06E-40 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS00095 c730267c60b0352999691be9048fa95c 306 Gene3D G3DSA:3.40.50.150 62 277 4.0E-41 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS08270 f44e931860fd78eeb2d2e8c02bac74ba 211 SUPERFAMILY SSF52374 7 200 9.38E-51 T 06-07-2017 CAK77_RS08270 f44e931860fd78eeb2d2e8c02bac74ba 211 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 6 201 30.044 T 06-07-2017 IPR005248 Probable nicotinate-nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|Reactome: R-HSA-196807 CAK77_RS08270 f44e931860fd78eeb2d2e8c02bac74ba 211 Gene3D G3DSA:3.40.50.620 6 203 6.1E-67 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS08270 f44e931860fd78eeb2d2e8c02bac74ba 211 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 9 72 1.8E-11 T 06-07-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CAK77_RS08270 f44e931860fd78eeb2d2e8c02bac74ba 211 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 10 200 3.0E-58 T 06-07-2017 IPR005248 Probable nicotinate-nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|Reactome: R-HSA-196807 CAK77_RS08270 f44e931860fd78eeb2d2e8c02bac74ba 211 Pfam PF01467 Cytidylyltransferase-like 10 173 1.2E-31 T 06-07-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CAK77_RS09285 389f365c4081a22715f953121f5a63f3 292 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 31 292 5.0E-96 T 06-07-2017 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 CAK77_RS09285 389f365c4081a22715f953121f5a63f3 292 Pfam PF02548 Ketopantoate hydroxymethyltransferase 32 287 1.2E-106 T 06-07-2017 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 CAK77_RS09285 389f365c4081a22715f953121f5a63f3 292 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 32 292 41.712 T 06-07-2017 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 CAK77_RS09285 389f365c4081a22715f953121f5a63f3 292 SUPERFAMILY SSF51621 32 291 4.71E-99 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAK77_RS09285 389f365c4081a22715f953121f5a63f3 292 PIRSF PIRSF000388 23 292 2.0E-111 T 06-07-2017 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 CAK77_RS09285 389f365c4081a22715f953121f5a63f3 292 Gene3D G3DSA:3.20.20.60 31 292 1.1E-110 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAK77_RS20610 5662ddd7d3f6cc8afaed2c00628fe1a2 440 Gene3D G3DSA:3.40.50.2000 22 280 6.9E-59 T 06-07-2017 CAK77_RS20610 5662ddd7d3f6cc8afaed2c00628fe1a2 440 Gene3D G3DSA:3.40.50.2000 281 413 1.7E-7 T 06-07-2017 CAK77_RS20610 5662ddd7d3f6cc8afaed2c00628fe1a2 440 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 25 73 4.7E-8 T 06-07-2017 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CAK77_RS20610 5662ddd7d3f6cc8afaed2c00628fe1a2 440 SUPERFAMILY SSF53756 22 438 2.23E-88 T 06-07-2017 CAK77_RS01905 ebb358382a240e52e111acee2d4c7585 409 PIRSF PIRSF000429 8 405 6.1E-68 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 CAK77_RS01905 ebb358382a240e52e111acee2d4c7585 409 ProSitePatterns PS00737 Thiolases signature 2. 342 358 - T 06-07-2017 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CAK77_RS01905 ebb358382a240e52e111acee2d4c7585 409 Gene3D G3DSA:3.40.47.10 215 236 4.0E-25 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS01905 ebb358382a240e52e111acee2d4c7585 409 Gene3D G3DSA:3.40.47.10 31 127 4.0E-25 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS01905 ebb358382a240e52e111acee2d4c7585 409 Pfam PF02803 Thiolase, C-terminal domain 280 387 4.4E-13 T 06-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CAK77_RS01905 ebb358382a240e52e111acee2d4c7585 409 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 88 106 - T 06-07-2017 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 CAK77_RS01905 ebb358382a240e52e111acee2d4c7585 409 SUPERFAMILY SSF53901 194 397 4.05E-47 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS01905 ebb358382a240e52e111acee2d4c7585 409 SUPERFAMILY SSF53901 13 127 4.05E-47 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS01905 ebb358382a240e52e111acee2d4c7585 409 Gene3D G3DSA:3.40.47.10 262 388 5.9E-27 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS01905 ebb358382a240e52e111acee2d4c7585 409 Gene3D G3DSA:3.40.47.10 159 196 5.9E-27 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS01905 ebb358382a240e52e111acee2d4c7585 409 Pfam PF00108 Thiolase, N-terminal domain 13 201 3.1E-18 T 06-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CAK77_RS12400 815cf1e911437631446cdc8697c32b05 142 Gene3D G3DSA:2.60.40.290 40 139 1.8E-31 T 06-07-2017 IPR012291 Cellulose-binding family II/chitobiase, carbohydrate-binding domain GO:0004553|GO:0030247 CAK77_RS12400 815cf1e911437631446cdc8697c32b05 142 SUPERFAMILY SSF49384 37 140 2.37E-32 T 06-07-2017 IPR008965 Carbohydrate-binding domain GO:0030246 CAK77_RS12400 815cf1e911437631446cdc8697c32b05 142 Pfam PF00553 Cellulose binding domain 41 139 8.9E-32 T 06-07-2017 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CAK77_RS12400 815cf1e911437631446cdc8697c32b05 142 SMART SM00637 40 140 1.5E-36 T 06-07-2017 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CAK77_RS01925 39f4bda9d8619678058045ee534626b3 504 PIRSF PIRSF000538 2 504 5.7E-156 T 06-07-2017 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CAK77_RS01925 39f4bda9d8619678058045ee534626b3 504 SUPERFAMILY SSF53067 4 259 5.76E-83 T 06-07-2017 CAK77_RS01925 39f4bda9d8619678058045ee534626b3 504 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 134 146 - T 06-07-2017 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CAK77_RS01925 39f4bda9d8619678058045ee534626b3 504 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 265 455 6.2E-64 T 06-07-2017 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 CAK77_RS01925 39f4bda9d8619678058045ee534626b3 504 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 367 387 - T 06-07-2017 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CAK77_RS01925 39f4bda9d8619678058045ee534626b3 504 Gene3D G3DSA:3.30.420.40 259 503 1.0E-100 T 06-07-2017 CAK77_RS01925 39f4bda9d8619678058045ee534626b3 504 SUPERFAMILY SSF53067 259 502 1.29E-80 T 06-07-2017 CAK77_RS01925 39f4bda9d8619678058045ee534626b3 504 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 6 256 5.8E-68 T 06-07-2017 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 CAK77_RS01925 39f4bda9d8619678058045ee534626b3 504 Hamap MF_00186 Glycerol kinase [glpK]. 2 502 54.211 T 06-07-2017 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 CAK77_RS01925 39f4bda9d8619678058045ee534626b3 504 Gene3D G3DSA:3.30.420.40 2 257 5.8E-97 T 06-07-2017 CAK77_RS01925 39f4bda9d8619678058045ee534626b3 504 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 4 501 9.7E-222 T 06-07-2017 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 CAK77_RS15920 a7a4ee8f2332157d4bfdd402d1ef2a2a 322 SUPERFAMILY SSF46785 228 318 7.02E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS15920 a7a4ee8f2332157d4bfdd402d1ef2a2a 322 Pfam PF01638 HxlR-like helix-turn-helix 240 318 3.9E-12 T 06-07-2017 IPR002577 Helix-turn-helix, HxlR type CAK77_RS15920 a7a4ee8f2332157d4bfdd402d1ef2a2a 322 Gene3D G3DSA:1.10.10.10 225 320 1.5E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS15920 a7a4ee8f2332157d4bfdd402d1ef2a2a 322 SUPERFAMILY SSF46689 6 86 3.54E-19 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS15920 a7a4ee8f2332157d4bfdd402d1ef2a2a 322 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 5.5E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS15920 a7a4ee8f2332157d4bfdd402d1ef2a2a 322 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 5.5E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS15920 a7a4ee8f2332157d4bfdd402d1ef2a2a 322 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 64 3.8E-13 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS15920 a7a4ee8f2332157d4bfdd402d1ef2a2a 322 Gene3D G3DSA:1.10.357.10 2 194 1.8E-31 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS21370 fc630765040b1ac1f7646fa097f41eb1 139 PIRSF PIRSF017349 1 138 1.7E-63 T 06-07-2017 IPR014487 Protein of unknown function DUF3151 CAK77_RS21370 fc630765040b1ac1f7646fa097f41eb1 139 Pfam PF11349 Protein of unknown function (DUF3151) 6 133 2.9E-57 T 06-07-2017 IPR014487 Protein of unknown function DUF3151 CAK77_RS01880 0844f45fe40bde975497c00dbc7fb24b 360 Gene3D G3DSA:3.90.1150.10 234 356 5.5E-5 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK77_RS01880 0844f45fe40bde975497c00dbc7fb24b 360 SUPERFAMILY SSF53383 16 358 3.06E-50 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK77_RS01880 0844f45fe40bde975497c00dbc7fb24b 360 Gene3D G3DSA:3.40.640.10 33 232 1.2E-36 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK77_RS01880 0844f45fe40bde975497c00dbc7fb24b 360 Pfam PF00266 Aminotransferase class-V 18 229 4.4E-27 T 06-07-2017 IPR000192 Aminotransferase class V domain CAK77_RS01880 0844f45fe40bde975497c00dbc7fb24b 360 Hamap MF_02038 Probable hercynylcysteine sulfoxide lyase [egtE]. 1 356 35.58 T 06-07-2017 IPR027563 Pyridoxal-phosphate-dependent protein EgtE CAK77_RS01880 0844f45fe40bde975497c00dbc7fb24b 360 TIGRFAM TIGR04343 egtE_PLP_lyase: ergothioneine biosynthesis PLP-dependent enzyme EgtE 3 355 6.1E-171 T 06-07-2017 IPR027563 Pyridoxal-phosphate-dependent protein EgtE CAK77_RS00025 a49fb83c98095c4bbd830f84c5ff8e5e 401 ProSitePatterns PS00617 RecF protein signature 1. 136 156 - T 06-07-2017 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 CAK77_RS00025 a49fb83c98095c4bbd830f84c5ff8e5e 401 SUPERFAMILY SSF52540 22 242 2.06E-38 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS00025 a49fb83c98095c4bbd830f84c5ff8e5e 401 SUPERFAMILY SSF52540 270 358 2.06E-38 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS00025 a49fb83c98095c4bbd830f84c5ff8e5e 401 ProSitePatterns PS00618 RecF protein signature 2. 337 355 - T 06-07-2017 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 CAK77_RS00025 a49fb83c98095c4bbd830f84c5ff8e5e 401 Pfam PF02463 RecF/RecN/SMC N terminal domain 21 370 1.4E-17 T 06-07-2017 IPR003395 RecF/RecN/SMC, N-terminal CAK77_RS00025 a49fb83c98095c4bbd830f84c5ff8e5e 401 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 401 96.228 T 06-07-2017 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 CAK77_RS00025 a49fb83c98095c4bbd830f84c5ff8e5e 401 Gene3D G3DSA:3.40.50.300 266 369 2.2E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS00025 a49fb83c98095c4bbd830f84c5ff8e5e 401 Gene3D G3DSA:3.40.50.300 21 186 2.2E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS00025 a49fb83c98095c4bbd830f84c5ff8e5e 401 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 20 387 2.0E-124 T 06-07-2017 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 CAK77_RS16845 5278301e6c851b55cb363ed305f8d9d7 482 Gene3D G3DSA:3.40.640.10 147 335 4.8E-44 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK77_RS16845 5278301e6c851b55cb363ed305f8d9d7 482 SUPERFAMILY SSF53383 117 466 1.86E-76 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK77_RS16845 5278301e6c851b55cb363ed305f8d9d7 482 Gene3D G3DSA:3.90.1150.10 336 466 1.8E-19 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK77_RS16845 5278301e6c851b55cb363ed305f8d9d7 482 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 64 80 2.2E-6 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK77_RS16845 5278301e6c851b55cb363ed305f8d9d7 482 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 50 64 2.2E-6 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK77_RS16845 5278301e6c851b55cb363ed305f8d9d7 482 Pfam PF00392 Bacterial regulatory proteins, gntR family 28 85 4.2E-12 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK77_RS16845 5278301e6c851b55cb363ed305f8d9d7 482 SMART SM00345 31 90 1.7E-9 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK77_RS16845 5278301e6c851b55cb363ed305f8d9d7 482 SUPERFAMILY SSF46785 23 91 3.96E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS16845 5278301e6c851b55cb363ed305f8d9d7 482 Gene3D G3DSA:1.10.10.10 23 86 3.0E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS16845 5278301e6c851b55cb363ed305f8d9d7 482 Pfam PF00155 Aminotransferase class I and II 141 456 5.0E-32 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAK77_RS00815 061a460a17b4ad4f2ff7792065acc64d 226 Gene3D G3DSA:3.40.50.1820 4 134 1.8E-27 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS00815 061a460a17b4ad4f2ff7792065acc64d 226 Gene3D G3DSA:3.40.50.1820 145 224 2.5E-6 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS00815 061a460a17b4ad4f2ff7792065acc64d 226 SUPERFAMILY SSF53474 6 224 1.0E-37 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS00815 061a460a17b4ad4f2ff7792065acc64d 226 Pfam PF12697 Alpha/beta hydrolase family 27 212 1.7E-17 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS02360 a1285003007b1fff296753297be237b8 323 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 129 322 1.7E-40 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS02360 a1285003007b1fff296753297be237b8 323 SUPERFAMILY SSF161098 109 309 1.83E-20 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS02360 a1285003007b1fff296753297be237b8 323 Gene3D G3DSA:1.10.3720.10 102 317 9.8E-23 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS06700 51cc5b4704189737ca1a7474da6b857c 354 TIGRFAM TIGR01900 dapE-gram_pos: succinyl-diaminopimelate desuccinylase 6 353 1.9E-155 T 06-07-2017 IPR010174 Succinyl-diaminopimelate desuccinylase, DapE GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 CAK77_RS06700 51cc5b4704189737ca1a7474da6b857c 354 Gene3D G3DSA:3.40.630.10 9 166 1.5E-39 T 06-07-2017 CAK77_RS06700 51cc5b4704189737ca1a7474da6b857c 354 Gene3D G3DSA:3.40.630.10 275 352 1.5E-39 T 06-07-2017 CAK77_RS06700 51cc5b4704189737ca1a7474da6b857c 354 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 65 74 - T 06-07-2017 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CAK77_RS06700 51cc5b4704189737ca1a7474da6b857c 354 Pfam PF07687 Peptidase dimerisation domain 166 263 5.9E-13 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAK77_RS06700 51cc5b4704189737ca1a7474da6b857c 354 Pfam PF01546 Peptidase family M20/M25/M40 66 352 7.0E-18 T 06-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CAK77_RS06700 51cc5b4704189737ca1a7474da6b857c 354 Gene3D G3DSA:3.30.70.360 167 272 2.1E-22 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAK77_RS06700 51cc5b4704189737ca1a7474da6b857c 354 SUPERFAMILY SSF55031 166 270 1.79E-18 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAK77_RS06700 51cc5b4704189737ca1a7474da6b857c 354 SUPERFAMILY SSF53187 274 352 1.47E-41 T 06-07-2017 CAK77_RS06700 51cc5b4704189737ca1a7474da6b857c 354 SUPERFAMILY SSF53187 9 178 1.47E-41 T 06-07-2017 CAK77_RS12480 2ef83c328bd860143476dbd837dbf391 301 Pfam PF00582 Universal stress protein family 10 146 1.8E-15 T 06-07-2017 IPR006016 UspA GO:0006950 CAK77_RS12480 2ef83c328bd860143476dbd837dbf391 301 Pfam PF00582 Universal stress protein family 156 293 2.3E-29 T 06-07-2017 IPR006016 UspA GO:0006950 CAK77_RS12480 2ef83c328bd860143476dbd837dbf391 301 SUPERFAMILY SSF52402 155 296 1.09E-34 T 06-07-2017 CAK77_RS12480 2ef83c328bd860143476dbd837dbf391 301 PRINTS PR01438 Universal stress protein signature 271 293 2.6E-14 T 06-07-2017 IPR006015 Universal stress protein A CAK77_RS12480 2ef83c328bd860143476dbd837dbf391 301 PRINTS PR01438 Universal stress protein signature 7 25 2.6E-14 T 06-07-2017 IPR006015 Universal stress protein A CAK77_RS12480 2ef83c328bd860143476dbd837dbf391 301 PRINTS PR01438 Universal stress protein signature 253 265 2.6E-14 T 06-07-2017 IPR006015 Universal stress protein A CAK77_RS12480 2ef83c328bd860143476dbd837dbf391 301 Gene3D G3DSA:3.40.50.620 141 293 3.2E-41 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS12480 2ef83c328bd860143476dbd837dbf391 301 Gene3D G3DSA:3.40.50.620 10 140 5.8E-23 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS12480 2ef83c328bd860143476dbd837dbf391 301 SUPERFAMILY SSF52402 10 148 9.21E-21 T 06-07-2017 CAK77_RS20140 f5a9245090d8dd1d50ffac25f07db46c 375 SUPERFAMILY SSF54292 275 374 4.85E-21 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK77_RS20140 f5a9245090d8dd1d50ffac25f07db46c 375 SUPERFAMILY SSF63380 70 157 1.34E-25 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CAK77_RS20140 f5a9245090d8dd1d50ffac25f07db46c 375 SUPERFAMILY SSF52343 170 286 2.75E-23 T 06-07-2017 CAK77_RS20140 f5a9245090d8dd1d50ffac25f07db46c 375 Gene3D G3DSA:3.10.20.30 278 373 2.3E-20 T 06-07-2017 IPR012675 Beta-grasp domain CAK77_RS20140 f5a9245090d8dd1d50ffac25f07db46c 375 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 325 333 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CAK77_RS20140 f5a9245090d8dd1d50ffac25f07db46c 375 Gene3D G3DSA:3.40.50.80 169 277 1.8E-20 T 06-07-2017 CAK77_RS20140 f5a9245090d8dd1d50ffac25f07db46c 375 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 303 366 2.6E-9 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK77_RS20140 f5a9245090d8dd1d50ffac25f07db46c 375 Pfam PF00970 Oxidoreductase FAD-binding domain 75 159 1.0E-5 T 06-07-2017 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 CAK77_RS20140 f5a9245090d8dd1d50ffac25f07db46c 375 Gene3D G3DSA:2.40.30.10 68 157 2.1E-31 T 06-07-2017 CAK77_RS20140 f5a9245090d8dd1d50ffac25f07db46c 375 PRINTS PR00409 Phthalate dioxygenase reductase family signature 97 109 2.3E-24 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 CAK77_RS20140 f5a9245090d8dd1d50ffac25f07db46c 375 PRINTS PR00409 Phthalate dioxygenase reductase family signature 147 161 2.3E-24 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 CAK77_RS20140 f5a9245090d8dd1d50ffac25f07db46c 375 PRINTS PR00409 Phthalate dioxygenase reductase family signature 133 147 2.3E-24 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 CAK77_RS20140 f5a9245090d8dd1d50ffac25f07db46c 375 PRINTS PR00409 Phthalate dioxygenase reductase family signature 87 97 2.3E-24 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 CAK77_RS20140 f5a9245090d8dd1d50ffac25f07db46c 375 PRINTS PR00409 Phthalate dioxygenase reductase family signature 109 123 2.3E-24 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 CAK77_RS20140 f5a9245090d8dd1d50ffac25f07db46c 375 PRINTS PR00409 Phthalate dioxygenase reductase family signature 250 258 2.3E-24 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 CAK77_RS16835 3615b3e640b9dd62598634e285792228 248 Gene3D G3DSA:1.10.260.40 155 232 1.2E-7 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK77_RS03765 9fc19d9bf17c3d5a407d148726752a4f 161 Pfam PF04224 Protein of unknown function, DUF417 21 152 9.8E-35 T 06-07-2017 IPR007339 Protein of unknown function DUF417 CAK77_RS07475 b9dc5797348e160e0c089a42dc626a36 309 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 92 1.3E-9 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAK77_RS07475 b9dc5797348e160e0c089a42dc626a36 309 SUPERFAMILY SSF50129 2 146 6.24E-37 T 06-07-2017 IPR011032 GroES-like CAK77_RS07475 b9dc5797348e160e0c089a42dc626a36 309 Pfam PF13602 Zinc-binding dehydrogenase 201 307 2.3E-16 T 06-07-2017 CAK77_RS07475 b9dc5797348e160e0c089a42dc626a36 309 Gene3D G3DSA:3.40.50.720 146 237 1.0E-18 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS07475 b9dc5797348e160e0c089a42dc626a36 309 SUPERFAMILY SSF51735 114 237 4.91E-28 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS07475 b9dc5797348e160e0c089a42dc626a36 309 Gene3D G3DSA:3.90.180.10 2 145 2.4E-47 T 06-07-2017 IPR011032 GroES-like CAK77_RS07475 b9dc5797348e160e0c089a42dc626a36 309 SMART SM00829 11 307 8.6E-27 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAK77_RS07475 b9dc5797348e160e0c089a42dc626a36 309 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 141 162 - T 06-07-2017 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 CAK77_RS22505 afcfabb63adf462af56341dc1951a4eb 399 Pfam PF01594 Domain of unknown function DUF20 22 347 3.3E-66 T 06-07-2017 IPR002549 Transmembrane protein TqsA-like CAK77_RS02135 930f960a8d76950d2fee009691bbb50b 82 Gene3D G3DSA:1.10.10.10 15 67 1.2E-4 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS02135 930f960a8d76950d2fee009691bbb50b 82 SUPERFAMILY SSF88659 27 70 9.16E-5 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS12405 4efe51b93db43876cf49411b8aea49d7 151 Gene3D G3DSA:2.60.40.1240 31 150 1.1E-34 T 06-07-2017 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain CAK77_RS12405 4efe51b93db43876cf49411b8aea49d7 151 Pfam PF09167 Domain of unknown function (DUF1942) 36 149 5.2E-35 T 06-07-2017 IPR015250 MPT63-like GO:0005615 CAK77_RS12405 4efe51b93db43876cf49411b8aea49d7 151 ProDom PD886639 ANTIGEN IMMUNOGENIC EXTRACELLULAR MPT63 MPB63 PRECURSOR IMMUNOPROTECTIVE SIGNAL SEQUENCING DIRECT 32 150 1.0E-45 T 06-07-2017 IPR015250 MPT63-like GO:0005615 CAK77_RS12405 4efe51b93db43876cf49411b8aea49d7 151 SUPERFAMILY SSF81982 30 150 1.29E-35 T 06-07-2017 IPR015250 MPT63-like GO:0005615 CAK77_RS22925 075217fa382e3632deebf4f332a5413c 316 Gene3D G3DSA:3.40.50.150 18 248 2.8E-21 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS22925 075217fa382e3632deebf4f332a5413c 316 SUPERFAMILY SSF53335 20 301 8.31E-76 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS22925 075217fa382e3632deebf4f332a5413c 316 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 22 290 5.5E-83 T 06-07-2017 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 CAK77_RS22925 075217fa382e3632deebf4f332a5413c 316 Pfam PF04072 Leucine carboxyl methyltransferase 24 209 4.0E-62 T 06-07-2017 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 CAK77_RS09470 68e91e672a302c89c59a8adc14eecf34 367 ProSitePatterns PS00770 Aminotransferases class-IV signature. 239 272 - T 06-07-2017 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 CAK77_RS09470 68e91e672a302c89c59a8adc14eecf34 367 Pfam PF01063 Amino-transferase class IV 75 322 5.5E-33 T 06-07-2017 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CAK77_RS09470 68e91e672a302c89c59a8adc14eecf34 367 Gene3D G3DSA:3.20.10.10 181 353 3.8E-69 T 06-07-2017 CAK77_RS09470 68e91e672a302c89c59a8adc14eecf34 367 PIRSF PIRSF006468 5 367 1.0E-133 T 06-07-2017 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|Reactome: R-HSA-70895 CAK77_RS09470 68e91e672a302c89c59a8adc14eecf34 367 TIGRFAM TIGR01123 ilvE_II: branched-chain amino acid aminotransferase 49 365 1.7E-139 T 06-07-2017 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|Reactome: R-HSA-70895 CAK77_RS09470 68e91e672a302c89c59a8adc14eecf34 367 Gene3D G3DSA:3.30.470.10 23 180 4.7E-67 T 06-07-2017 CAK77_RS09470 68e91e672a302c89c59a8adc14eecf34 367 SUPERFAMILY SSF56752 12 363 6.41E-117 T 06-07-2017 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CAK77_RS11005 641fade71a5fcd799e10cd85ef9e27d9 303 Gene3D G3DSA:2.60.120.620 32 282 9.5E-45 T 06-07-2017 CAK77_RS11005 641fade71a5fcd799e10cd85ef9e27d9 303 SUPERFAMILY SSF51197 33 296 1.19E-54 T 06-07-2017 CAK77_RS11005 641fade71a5fcd799e10cd85ef9e27d9 303 TIGRFAM TIGR02408 ectoine_ThpD: ectoine hydroxylase 22 295 1.0E-117 T 06-07-2017 IPR012774 Ectoine dioxygenase GO:0016706|GO:0055114 CAK77_RS11005 641fade71a5fcd799e10cd85ef9e27d9 303 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 46 259 1.1E-26 T 06-07-2017 IPR008775 Phytanoyl-CoA dioxygenase CAK77_RS04680 cb4717916dc5e5a8a1287b581dcb8a48 271 Gene3D G3DSA:3.40.50.720 10 262 5.3E-82 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS04680 cb4717916dc5e5a8a1287b581dcb8a48 271 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 157 2.9E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS04680 cb4717916dc5e5a8a1287b581dcb8a48 271 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 170 189 2.9E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS04680 cb4717916dc5e5a8a1287b581dcb8a48 271 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 96 107 2.9E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS04680 cb4717916dc5e5a8a1287b581dcb8a48 271 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 28 259 1.2E-57 T 06-07-2017 CAK77_RS04680 cb4717916dc5e5a8a1287b581dcb8a48 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 224 244 5.9E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS04680 cb4717916dc5e5a8a1287b581dcb8a48 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 21 38 5.9E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS04680 cb4717916dc5e5a8a1287b581dcb8a48 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 96 107 5.9E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS04680 cb4717916dc5e5a8a1287b581dcb8a48 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 189 5.9E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS04680 cb4717916dc5e5a8a1287b581dcb8a48 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 143 159 5.9E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS04680 cb4717916dc5e5a8a1287b581dcb8a48 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 191 208 5.9E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS04680 cb4717916dc5e5a8a1287b581dcb8a48 271 SUPERFAMILY SSF51735 14 262 1.4E-76 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS04680 cb4717916dc5e5a8a1287b581dcb8a48 271 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 20 201 2.4E-4 T 06-07-2017 CAK77_RS18035 91aebb895e239293aba418459af39f45 264 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 19 257 2.0E-38 T 06-07-2017 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAK77_RS18035 91aebb895e239293aba418459af39f45 264 SUPERFAMILY SSF50037 216 257 2.98E-5 T 06-07-2017 IPR008988 Transcriptional repressor, C-terminal CAK77_RS18035 91aebb895e239293aba418459af39f45 264 Gene3D G3DSA:3.30.930.10 15 207 5.7E-50 T 06-07-2017 CAK77_RS18035 91aebb895e239293aba418459af39f45 264 Gene3D G3DSA:2.30.30.100 220 256 7.3E-5 T 06-07-2017 CAK77_RS18035 91aebb895e239293aba418459af39f45 264 SUPERFAMILY SSF55681 15 192 3.48E-43 T 06-07-2017 CAK77_RS18035 91aebb895e239293aba418459af39f45 264 Pfam PF02237 Biotin protein ligase C terminal domain 210 257 1.8E-5 T 06-07-2017 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAK77_RS18035 91aebb895e239293aba418459af39f45 264 Pfam PF03099 Biotin/lipoate A/B protein ligase family 46 146 3.2E-9 T 06-07-2017 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 CAK77_RS02720 b8c7c565e1625f6bc5d53aece702325a 296 Pfam PF01171 PP-loop family 4 172 1.6E-29 T 06-07-2017 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 CAK77_RS02720 b8c7c565e1625f6bc5d53aece702325a 296 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 1 276 17.711 T 06-07-2017 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CAK77_RS02720 b8c7c565e1625f6bc5d53aece702325a 296 SUPERFAMILY SSF82829 184 276 5.49E-12 T 06-07-2017 CAK77_RS02720 b8c7c565e1625f6bc5d53aece702325a 296 Gene3D G3DSA:3.40.50.620 4 89 1.1E-7 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS02720 b8c7c565e1625f6bc5d53aece702325a 296 Pfam PF09179 TilS substrate binding domain 217 276 4.7E-10 T 06-07-2017 IPR015262 tRNA(Ile)-lysidine synthase , substrate-binding domain GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CAK77_RS02720 b8c7c565e1625f6bc5d53aece702325a 296 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 4 175 1.6E-34 T 06-07-2017 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CAK77_RS02720 b8c7c565e1625f6bc5d53aece702325a 296 SUPERFAMILY SSF52402 3 203 2.87E-39 T 06-07-2017 CAK77_RS04020 989d9643df211fdca60f0f1af58200c7 258 SMART SM00382 29 223 2.6E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS04020 989d9643df211fdca60f0f1af58200c7 258 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK77_RS04020 989d9643df211fdca60f0f1af58200c7 258 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 5 258 2.1E-115 T 06-07-2017 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 CAK77_RS04020 989d9643df211fdca60f0f1af58200c7 258 Pfam PF00005 ABC transporter 21 176 1.7E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK77_RS04020 989d9643df211fdca60f0f1af58200c7 258 SUPERFAMILY SSF52540 5 245 3.9E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS04020 989d9643df211fdca60f0f1af58200c7 258 Gene3D G3DSA:3.40.50.300 3 250 1.5E-66 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS13985 e0645a9155f34fa906814a35e14c853a 1099 Pfam PF01841 Transglutaminase-like superfamily 136 254 5.5E-18 T 06-07-2017 IPR002931 Transglutaminase-like CAK77_RS13985 e0645a9155f34fa906814a35e14c853a 1099 Pfam PF09899 Putative amidoligase enzyme (DUF2126) 284 1091 0.0 T 06-07-2017 IPR018667 Domain of unknown function DUF2126 CAK77_RS13985 e0645a9155f34fa906814a35e14c853a 1099 Pfam PF08379 Bacterial transglutaminase-like N-terminal region 6 82 1.3E-24 T 06-07-2017 IPR013589 Bacterial transglutaminase-like, N-terminal CAK77_RS13985 e0645a9155f34fa906814a35e14c853a 1099 Gene3D G3DSA:3.90.260.10 183 256 4.7E-10 T 06-07-2017 IPR002931 Transglutaminase-like CAK77_RS13985 e0645a9155f34fa906814a35e14c853a 1099 SUPERFAMILY SSF54001 9 345 1.28E-59 T 06-07-2017 CAK77_RS13985 e0645a9155f34fa906814a35e14c853a 1099 SMART SM00460 180 256 4.8E-20 T 06-07-2017 IPR002931 Transglutaminase-like CAK77_RS23065 cd60f075a4507f7484f7273d379a72fc 196 SUPERFAMILY SSF46689 3 69 4.67E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS23065 cd60f075a4507f7484f7273d379a72fc 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 54 9.5E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS23065 cd60f075a4507f7484f7273d379a72fc 196 SUPERFAMILY SSF48498 74 179 1.87E-17 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS23065 cd60f075a4507f7484f7273d379a72fc 196 Gene3D G3DSA:1.10.357.10 4 181 3.0E-21 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS22190 5be1765d2916bac0fab637d6885b13e1 295 Pfam PF03741 Integral membrane protein TerC family 16 205 3.3E-49 T 06-07-2017 IPR005496 Integral membrane protein TerC GO:0016021 CAK77_RS15155 d333e0acc0d0237185a7d942f8467d39 313 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 5 287 6.9E-69 T 06-07-2017 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 CAK77_RS15155 d333e0acc0d0237185a7d942f8467d39 313 Gene3D G3DSA:1.10.287.890 197 279 1.3E-19 T 06-07-2017 CAK77_RS15155 d333e0acc0d0237185a7d942f8467d39 313 Gene3D G3DSA:3.40.50.300 2 169 8.4E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS15155 d333e0acc0d0237185a7d942f8467d39 313 SUPERFAMILY SSF52540 5 147 1.12E-15 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS15155 d333e0acc0d0237185a7d942f8467d39 313 Pfam PF01715 IPP transferase 37 281 9.1E-69 T 06-07-2017 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 CAK77_RS15155 d333e0acc0d0237185a7d942f8467d39 313 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 4 300 25.421 T 06-07-2017 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 CAK77_RS13510 ac12d65b3b64ce2dbec00969f62d88f0 325 Pfam PF00107 Zinc-binding dehydrogenase 149 278 1.6E-24 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAK77_RS13510 ac12d65b3b64ce2dbec00969f62d88f0 325 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 87 4.2E-12 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAK77_RS13510 ac12d65b3b64ce2dbec00969f62d88f0 325 Gene3D G3DSA:3.40.50.720 145 259 2.8E-26 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS13510 ac12d65b3b64ce2dbec00969f62d88f0 325 SMART SM00829 10 323 7.0E-18 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAK77_RS13510 ac12d65b3b64ce2dbec00969f62d88f0 325 SUPERFAMILY SSF51735 109 279 1.03E-40 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS13510 ac12d65b3b64ce2dbec00969f62d88f0 325 SUPERFAMILY SSF50129 8 139 1.98E-35 T 06-07-2017 IPR011032 GroES-like CAK77_RS13510 ac12d65b3b64ce2dbec00969f62d88f0 325 Gene3D G3DSA:3.90.180.10 1 144 5.4E-41 T 06-07-2017 IPR011032 GroES-like CAK77_RS11925 3fb6da562993d9067ada972b793fc86d 257 Pfam PF12710 haloacid dehalogenase-like hydrolase 24 207 2.9E-33 T 06-07-2017 CAK77_RS11925 3fb6da562993d9067ada972b793fc86d 257 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 24 221 1.7E-47 T 06-07-2017 IPR006385 HAD-superfamily hydrolase, subfamily IB, PSPase-like, bacterial CAK77_RS11925 3fb6da562993d9067ada972b793fc86d 257 SUPERFAMILY SSF56784 24 228 1.13E-27 T 06-07-2017 IPR023214 HAD-like domain CAK77_RS11925 3fb6da562993d9067ada972b793fc86d 257 Gene3D G3DSA:3.40.50.1000 92 238 3.6E-38 T 06-07-2017 IPR023214 HAD-like domain CAK77_RS11925 3fb6da562993d9067ada972b793fc86d 257 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 24 210 1.5E-21 T 06-07-2017 IPR006383 HAD-superfamily hydrolase, subfamily IB, PSPase-like GO:0008152|GO:0016791 CAK77_RS09860 63d57d6985809b736ff5ff98588ee53c 421 Gene3D G3DSA:3.40.47.10 292 415 8.4E-11 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS09860 63d57d6985809b736ff5ff98588ee53c 421 SUPERFAMILY SSF53901 1 263 1.48E-37 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS09860 63d57d6985809b736ff5ff98588ee53c 421 Gene3D G3DSA:3.40.47.10 1 266 1.2E-33 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS09860 63d57d6985809b736ff5ff98588ee53c 421 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 284 373 5.0E-6 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAK77_RS09860 63d57d6985809b736ff5ff98588ee53c 421 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1 258 9.9E-21 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAK77_RS09860 63d57d6985809b736ff5ff98588ee53c 421 SUPERFAMILY SSF53901 228 415 3.54E-22 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS12840 2a5ed2b4f1a335eaa540e72d10e33c50 276 Gene3D G3DSA:3.40.50.1000 14 99 3.5E-24 T 06-07-2017 IPR023214 HAD-like domain CAK77_RS12840 2a5ed2b4f1a335eaa540e72d10e33c50 276 Gene3D G3DSA:3.40.50.1000 195 272 3.5E-24 T 06-07-2017 IPR023214 HAD-like domain CAK77_RS12840 2a5ed2b4f1a335eaa540e72d10e33c50 276 Gene3D G3DSA:3.30.70.1410 118 194 3.3E-21 T 06-07-2017 CAK77_RS12840 2a5ed2b4f1a335eaa540e72d10e33c50 276 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 14 239 6.9E-12 T 06-07-2017 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CAK77_RS12840 2a5ed2b4f1a335eaa540e72d10e33c50 276 Pfam PF05116 Sucrose-6F-phosphate phosphohydrolase 14 269 8.7E-20 T 06-07-2017 IPR006380 Sucrose-phosphatase, N-terminal CAK77_RS12840 2a5ed2b4f1a335eaa540e72d10e33c50 276 SUPERFAMILY SSF56784 13 272 2.07E-23 T 06-07-2017 IPR023214 HAD-like domain CAK77_RS08835 c7e10059fde999ecf36ce0c204eb02c2 363 Gene3D G3DSA:3.30.70.270 209 363 3.6E-35 T 06-07-2017 CAK77_RS08835 c7e10059fde999ecf36ce0c204eb02c2 363 SUPERFAMILY SSF55073 213 363 1.41E-29 T 06-07-2017 IPR029787 Nucleotide cyclase CAK77_RS08835 c7e10059fde999ecf36ce0c204eb02c2 363 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 206 363 7.7E-28 T 06-07-2017 IPR000160 GGDEF domain CAK77_RS08835 c7e10059fde999ecf36ce0c204eb02c2 363 Pfam PF00990 Diguanylate cyclase, GGDEF domain 208 363 7.8E-29 T 06-07-2017 IPR000160 GGDEF domain CAK77_RS08835 c7e10059fde999ecf36ce0c204eb02c2 363 SMART SM00267 197 362 3.4E-27 T 06-07-2017 IPR000160 GGDEF domain CAK77_RS09020 42ad82c1cd5412fb73f529cbf0ecc6b2 162 SUPERFAMILY SSF53474 21 147 1.33E-6 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS09020 42ad82c1cd5412fb73f529cbf0ecc6b2 162 Gene3D G3DSA:3.40.50.1820 49 147 7.7E-6 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS18650 be04cb7d0bee23a987a7db66e561a09e 405 Gene3D G3DSA:2.40.37.10 242 401 8.5E-53 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CAK77_RS18650 be04cb7d0bee23a987a7db66e561a09e 405 PRINTS PR00992 Alanine racemase signature 324 341 8.4E-66 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAK77_RS18650 be04cb7d0bee23a987a7db66e561a09e 405 PRINTS PR00992 Alanine racemase signature 179 190 8.4E-66 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAK77_RS18650 be04cb7d0bee23a987a7db66e561a09e 405 PRINTS PR00992 Alanine racemase signature 81 99 8.4E-66 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAK77_RS18650 be04cb7d0bee23a987a7db66e561a09e 405 PRINTS PR00992 Alanine racemase signature 303 318 8.4E-66 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAK77_RS18650 be04cb7d0bee23a987a7db66e561a09e 405 PRINTS PR00992 Alanine racemase signature 381 394 8.4E-66 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAK77_RS18650 be04cb7d0bee23a987a7db66e561a09e 405 PRINTS PR00992 Alanine racemase signature 45 61 8.4E-66 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAK77_RS18650 be04cb7d0bee23a987a7db66e561a09e 405 PRINTS PR00992 Alanine racemase signature 142 154 8.4E-66 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAK77_RS18650 be04cb7d0bee23a987a7db66e561a09e 405 PRINTS PR00992 Alanine racemase signature 222 249 8.4E-66 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAK77_RS18650 be04cb7d0bee23a987a7db66e561a09e 405 PRINTS PR00992 Alanine racemase signature 286 301 8.4E-66 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAK77_RS18650 be04cb7d0bee23a987a7db66e561a09e 405 Pfam PF01168 Alanine racemase, N-terminal domain 27 249 6.4E-66 T 06-07-2017 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAK77_RS18650 be04cb7d0bee23a987a7db66e561a09e 405 Hamap MF_01201 Alanine racemase. 20 399 32.175 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAK77_RS18650 be04cb7d0bee23a987a7db66e561a09e 405 Gene3D G3DSA:3.20.20.10 29 241 1.6E-69 T 06-07-2017 IPR029066 PLP-binding barrel CAK77_RS18650 be04cb7d0bee23a987a7db66e561a09e 405 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 50 60 - T 06-07-2017 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAK77_RS18650 be04cb7d0bee23a987a7db66e561a09e 405 SMART SM01005 270 399 7.5E-60 T 06-07-2017 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAK77_RS18650 be04cb7d0bee23a987a7db66e561a09e 405 SUPERFAMILY SSF50621 264 400 6.98E-45 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CAK77_RS18650 be04cb7d0bee23a987a7db66e561a09e 405 TIGRFAM TIGR00492 alr: alanine racemase 23 398 1.3E-92 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAK77_RS18650 be04cb7d0bee23a987a7db66e561a09e 405 Pfam PF00842 Alanine racemase, C-terminal domain 270 398 1.2E-35 T 06-07-2017 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAK77_RS18650 be04cb7d0bee23a987a7db66e561a09e 405 SUPERFAMILY SSF51419 27 253 1.74E-61 T 06-07-2017 IPR029066 PLP-binding barrel CAK77_RS06950 7576138c6d17d8ce849ded67f99556f0 278 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK77_RS06950 7576138c6d17d8ce849ded67f99556f0 278 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 2.0E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06950 7576138c6d17d8ce849ded67f99556f0 278 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 2.0E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06950 7576138c6d17d8ce849ded67f99556f0 278 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 2.0E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06950 7576138c6d17d8ce849ded67f99556f0 278 Gene3D G3DSA:3.40.50.720 5 241 4.2E-64 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS06950 7576138c6d17d8ce849ded67f99556f0 278 Pfam PF00106 short chain dehydrogenase 7 201 6.7E-50 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06950 7576138c6d17d8ce849ded67f99556f0 278 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 193 0.0034 T 06-07-2017 CAK77_RS06950 7576138c6d17d8ce849ded67f99556f0 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 2.6E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06950 7576138c6d17d8ce849ded67f99556f0 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 2.6E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06950 7576138c6d17d8ce849ded67f99556f0 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 2.6E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06950 7576138c6d17d8ce849ded67f99556f0 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 2.6E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06950 7576138c6d17d8ce849ded67f99556f0 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 2.6E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06950 7576138c6d17d8ce849ded67f99556f0 278 SUPERFAMILY SSF51735 3 268 1.16E-63 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS06965 32161fe139f54833b34e33e0a41c3199 384 Pfam PF13556 PucR C-terminal helix-turn-helix domain 323 380 2.1E-17 T 06-07-2017 IPR025736 PucR C-terminal helix-turn-helix domain CAK77_RS04225 3079ed06e11a812973a3d0979738b33c 256 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 15 227 0.0018 T 06-07-2017 CAK77_RS04225 3079ed06e11a812973a3d0979738b33c 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 163 182 3.9E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS04225 3079ed06e11a812973a3d0979738b33c 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 90 101 3.9E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS04225 3079ed06e11a812973a3d0979738b33c 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 143 151 3.9E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS04225 3079ed06e11a812973a3d0979738b33c 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 184 201 3.3E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS04225 3079ed06e11a812973a3d0979738b33c 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 3.3E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS04225 3079ed06e11a812973a3d0979738b33c 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 182 3.3E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS04225 3079ed06e11a812973a3d0979738b33c 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 137 153 3.3E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS04225 3079ed06e11a812973a3d0979738b33c 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 90 101 3.3E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS04225 3079ed06e11a812973a3d0979738b33c 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 16 33 3.3E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS04225 3079ed06e11a812973a3d0979738b33c 256 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 150 178 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK77_RS04225 3079ed06e11a812973a3d0979738b33c 256 SUPERFAMILY SSF51735 14 255 8.34E-78 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS04225 3079ed06e11a812973a3d0979738b33c 256 Gene3D G3DSA:3.40.50.720 7 255 7.2E-81 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS04225 3079ed06e11a812973a3d0979738b33c 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 23 253 2.1E-56 T 06-07-2017 CAK77_RS10325 04ee981624865b20a7686386a93baea6 1155 Gene3D G3DSA:3.40.50.980 551 702 1.6E-33 T 06-07-2017 CAK77_RS10325 04ee981624865b20a7686386a93baea6 1155 Gene3D G3DSA:1.10.1200.10 12 75 2.4E-6 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS10325 04ee981624865b20a7686386a93baea6 1155 Gene3D G3DSA:1.10.1200.10 1043 1125 2.2E-18 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS10325 04ee981624865b20a7686386a93baea6 1155 Pfam PF08415 Nonribosomal peptide synthase 413 469 6.3E-14 T 06-07-2017 IPR013624 Non-ribosomal peptide synthetase CAK77_RS10325 04ee981624865b20a7686386a93baea6 1155 Gene3D G3DSA:3.30.300.30 942 1038 5.7E-26 T 06-07-2017 CAK77_RS10325 04ee981624865b20a7686386a93baea6 1155 SUPERFAMILY SSF52777 94 289 8.0E-26 T 06-07-2017 CAK77_RS10325 04ee981624865b20a7686386a93baea6 1155 Gene3D G3DSA:2.30.38.10 862 938 5.4E-25 T 06-07-2017 CAK77_RS10325 04ee981624865b20a7686386a93baea6 1155 Pfam PF00668 Condensation domain 98 390 1.4E-39 T 06-07-2017 IPR001242 Condensation domain CAK77_RS10325 04ee981624865b20a7686386a93baea6 1155 Gene3D G3DSA:3.40.50.980 703 853 7.0E-37 T 06-07-2017 CAK77_RS10325 04ee981624865b20a7686386a93baea6 1155 SUPERFAMILY SSF56801 545 1066 1.83E-128 T 06-07-2017 CAK77_RS10325 04ee981624865b20a7686386a93baea6 1155 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 580 972 2.4E-117 T 06-07-2017 IPR010071 Amino acid adenylation domain CAK77_RS10325 04ee981624865b20a7686386a93baea6 1155 SUPERFAMILY SSF52777 276 519 1.45E-41 T 06-07-2017 CAK77_RS10325 04ee981624865b20a7686386a93baea6 1155 ProSitePatterns PS00455 Putative AMP-binding domain signature. 693 704 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK77_RS10325 04ee981624865b20a7686386a93baea6 1155 SUPERFAMILY SSF47336 1048 1120 1.7E-12 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS10325 04ee981624865b20a7686386a93baea6 1155 SUPERFAMILY SSF47336 7 111 2.75E-8 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS10325 04ee981624865b20a7686386a93baea6 1155 Pfam PF00501 AMP-binding enzyme 556 948 1.5E-87 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK77_RS10325 04ee981624865b20a7686386a93baea6 1155 Pfam PF00550 Phosphopantetheine attachment site 1055 1119 1.8E-8 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS10325 04ee981624865b20a7686386a93baea6 1155 Pfam PF00550 Phosphopantetheine attachment site 8 72 9.1E-7 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS17875 1688d5f4bf2c1485ae1c0050f2d28f69 331 Pfam PF04909 Amidohydrolase 35 330 2.7E-36 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAK77_RS17875 1688d5f4bf2c1485ae1c0050f2d28f69 331 SUPERFAMILY SSF51556 7 330 3.81E-79 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK77_RS17875 1688d5f4bf2c1485ae1c0050f2d28f69 331 Gene3D G3DSA:3.20.20.140 4 329 1.9E-88 T 06-07-2017 CAK77_RS18005 5c4181186177a0208ad84808a7b190a1 401 SUPERFAMILY SSF52440 5 98 8.34E-20 T 06-07-2017 IPR016185 Pre-ATP-grasp domain CAK77_RS18005 5c4181186177a0208ad84808a7b190a1 401 Gene3D G3DSA:3.40.50.20 5 111 3.4E-27 T 06-07-2017 IPR016185 Pre-ATP-grasp domain CAK77_RS18005 5c4181186177a0208ad84808a7b190a1 401 Gene3D G3DSA:3.30.470.20 143 398 6.7E-80 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAK77_RS18005 5c4181186177a0208ad84808a7b190a1 401 Pfam PF02222 ATP-grasp domain 113 284 2.3E-49 T 06-07-2017 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type CAK77_RS18005 5c4181186177a0208ad84808a7b190a1 401 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 7 365 3.0E-118 T 06-07-2017 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 CAK77_RS18005 5c4181186177a0208ad84808a7b190a1 401 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 6 366 37.402 T 06-07-2017 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 CAK77_RS18005 5c4181186177a0208ad84808a7b190a1 401 SUPERFAMILY SSF56059 103 304 1.38E-54 T 06-07-2017 CAK77_RS18005 5c4181186177a0208ad84808a7b190a1 401 SUPERFAMILY SSF51246 310 369 7.85E-13 T 06-07-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAK77_RS21975 64e03f310b623402d6533b44e48ae210 248 SUPERFAMILY SSF52499 49 246 7.33E-47 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAK77_RS21975 64e03f310b623402d6533b44e48ae210 248 Gene3D G3DSA:3.40.50.850 49 247 7.6E-49 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAK77_RS21975 64e03f310b623402d6533b44e48ae210 248 Pfam PF00857 Isochorismatase family 67 239 1.8E-33 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAK77_RS21975 64e03f310b623402d6533b44e48ae210 248 PRINTS PR01398 Isochorismatase signature 147 169 1.3E-28 T 06-07-2017 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 CAK77_RS21975 64e03f310b623402d6533b44e48ae210 248 PRINTS PR01398 Isochorismatase signature 221 238 1.3E-28 T 06-07-2017 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 CAK77_RS21975 64e03f310b623402d6533b44e48ae210 248 PRINTS PR01398 Isochorismatase signature 98 115 1.3E-28 T 06-07-2017 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 CAK77_RS21975 64e03f310b623402d6533b44e48ae210 248 PRINTS PR01398 Isochorismatase signature 115 134 1.3E-28 T 06-07-2017 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 CAK77_RS21975 64e03f310b623402d6533b44e48ae210 248 PRINTS PR01398 Isochorismatase signature 203 221 1.3E-28 T 06-07-2017 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 CAK77_RS23945 73b6a1baa31a0cfe59ad96bca8cf03a6 483 Pfam PF00512 His Kinase A (phospho-acceptor) domain 267 331 2.2E-10 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK77_RS23945 73b6a1baa31a0cfe59ad96bca8cf03a6 483 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 373 482 4.6E-23 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS23945 73b6a1baa31a0cfe59ad96bca8cf03a6 483 SUPERFAMILY SSF158472 215 262 1.26E-5 T 06-07-2017 CAK77_RS23945 73b6a1baa31a0cfe59ad96bca8cf03a6 483 Gene3D G3DSA:3.30.565.10 321 482 3.4E-37 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS23945 73b6a1baa31a0cfe59ad96bca8cf03a6 483 Pfam PF00672 HAMP domain 195 262 6.7E-11 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAK77_RS23945 73b6a1baa31a0cfe59ad96bca8cf03a6 483 SMART SM00388 267 332 1.5E-9 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK77_RS23945 73b6a1baa31a0cfe59ad96bca8cf03a6 483 Gene3D G3DSA:1.10.287.130 257 320 6.8E-11 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK77_RS23945 73b6a1baa31a0cfe59ad96bca8cf03a6 483 PRINTS PR00344 Bacterial sensor protein C-terminal signature 467 480 2.8E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK77_RS23945 73b6a1baa31a0cfe59ad96bca8cf03a6 483 PRINTS PR00344 Bacterial sensor protein C-terminal signature 426 436 2.8E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK77_RS23945 73b6a1baa31a0cfe59ad96bca8cf03a6 483 PRINTS PR00344 Bacterial sensor protein C-terminal signature 443 461 2.8E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK77_RS23945 73b6a1baa31a0cfe59ad96bca8cf03a6 483 PRINTS PR00344 Bacterial sensor protein C-terminal signature 408 422 2.8E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK77_RS23945 73b6a1baa31a0cfe59ad96bca8cf03a6 483 SMART SM00387 373 483 1.9E-35 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS23945 73b6a1baa31a0cfe59ad96bca8cf03a6 483 SUPERFAMILY SSF55874 321 481 2.88E-37 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS23945 73b6a1baa31a0cfe59ad96bca8cf03a6 483 SUPERFAMILY SSF47384 250 332 8.24E-14 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK77_RS23945 73b6a1baa31a0cfe59ad96bca8cf03a6 483 SMART SM00304 213 266 2.7E-8 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAK77_RS01690 62ee85a2322d23921d0c0ab9c5231cc8 78 TIGRFAM TIGR00009 L28: ribosomal protein bL28 2 57 5.9E-23 T 06-07-2017 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS01690 62ee85a2322d23921d0c0ab9c5231cc8 78 Gene3D G3DSA:2.30.170.40 2 77 6.9E-31 T 06-07-2017 CAK77_RS01690 62ee85a2322d23921d0c0ab9c5231cc8 78 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 71 20.65 T 06-07-2017 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS01690 62ee85a2322d23921d0c0ab9c5231cc8 78 SUPERFAMILY SSF143800 2 77 4.12E-26 T 06-07-2017 CAK77_RS01690 62ee85a2322d23921d0c0ab9c5231cc8 78 Pfam PF00830 Ribosomal L28 family 4 61 9.8E-23 T 06-07-2017 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS05420 36ab9978e5bdb4d835cadf69df78d218 175 Pfam PF00994 Probable molybdopterin binding domain 24 161 1.1E-25 T 06-07-2017 IPR001453 MoaB/Mog domain CAK77_RS05420 36ab9978e5bdb4d835cadf69df78d218 175 Gene3D G3DSA:3.40.980.10 22 171 5.0E-39 T 06-07-2017 IPR001453 MoaB/Mog domain CAK77_RS05420 36ab9978e5bdb4d835cadf69df78d218 175 SUPERFAMILY SSF53218 23 170 9.55E-33 T 06-07-2017 IPR001453 MoaB/Mog domain CAK77_RS05420 36ab9978e5bdb4d835cadf69df78d218 175 SMART SM00852 23 166 7.0E-17 T 06-07-2017 IPR001453 MoaB/Mog domain CAK77_RS05420 36ab9978e5bdb4d835cadf69df78d218 175 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 23 159 4.2E-28 T 06-07-2017 IPR001453 MoaB/Mog domain CAK77_RS10670 e732e398841187e6d8036ffff29aa3b2 337 SMART SM00279 211 246 1.5E-11 T 06-07-2017 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 CAK77_RS10670 e732e398841187e6d8036ffff29aa3b2 337 SUPERFAMILY SSF47807 214 329 1.26E-19 T 06-07-2017 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 CAK77_RS10670 e732e398841187e6d8036ffff29aa3b2 337 SUPERFAMILY SSF88723 13 174 7.11E-35 T 06-07-2017 IPR029060 PIN domain-like CAK77_RS10670 e732e398841187e6d8036ffff29aa3b2 337 Gene3D G3DSA:1.10.150.20 204 275 1.4E-19 T 06-07-2017 CAK77_RS10670 e732e398841187e6d8036ffff29aa3b2 337 SMART SM00475 12 303 5.4E-88 T 06-07-2017 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 CAK77_RS10670 e732e398841187e6d8036ffff29aa3b2 337 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 213 298 1.7E-18 T 06-07-2017 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 CAK77_RS10670 e732e398841187e6d8036ffff29aa3b2 337 Gene3D G3DSA:3.40.50.1010 10 203 2.4E-47 T 06-07-2017 IPR029060 PIN domain-like CAK77_RS10670 e732e398841187e6d8036ffff29aa3b2 337 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 14 204 1.0E-45 T 06-07-2017 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 CAK77_RS19675 2b1a60bd1aa51a0f59600af14b2df8b2 328 Pfam PF00348 Polyprenyl synthetase 36 278 3.3E-57 T 06-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 CAK77_RS19675 2b1a60bd1aa51a0f59600af14b2df8b2 328 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 208 220 - T 06-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 CAK77_RS19675 2b1a60bd1aa51a0f59600af14b2df8b2 328 SUPERFAMILY SSF48576 14 327 9.21E-78 T 06-07-2017 IPR008949 Isoprenoid synthase domain CAK77_RS19675 2b1a60bd1aa51a0f59600af14b2df8b2 328 Gene3D G3DSA:1.10.600.10 12 326 8.1E-88 T 06-07-2017 IPR008949 Isoprenoid synthase domain CAK77_RS23775 c46c10bed86e275cca10425a88654008 188 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 64 4.1E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS23775 c46c10bed86e275cca10425a88654008 188 ProSitePatterns PS01081 TetR-type HTH domain signature. 32 63 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CAK77_RS23775 c46c10bed86e275cca10425a88654008 188 SUPERFAMILY SSF46689 12 88 2.82E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS23775 c46c10bed86e275cca10425a88654008 188 Gene3D G3DSA:1.10.357.10 7 183 1.1E-25 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS23775 c46c10bed86e275cca10425a88654008 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 2.6E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS23775 c46c10bed86e275cca10425a88654008 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 2.6E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS12730 ea5b2a91e805b0059e09acafc6adff32 224 Gene3D G3DSA:1.10.10.10 145 198 3.5E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS12730 ea5b2a91e805b0059e09acafc6adff32 224 SMART SM01012 140 195 5.8E-14 T 06-07-2017 IPR005561 ANTAR domain GO:0003723 CAK77_RS12730 ea5b2a91e805b0059e09acafc6adff32 224 Pfam PF08447 PAS fold 43 128 1.0E-12 T 06-07-2017 IPR013655 PAS fold-3 GO:0005515 CAK77_RS12730 ea5b2a91e805b0059e09acafc6adff32 224 Pfam PF03861 ANTAR domain 146 193 5.4E-14 T 06-07-2017 IPR005561 ANTAR domain GO:0003723 CAK77_RS12730 ea5b2a91e805b0059e09acafc6adff32 224 Gene3D G3DSA:3.30.450.20 31 133 1.1E-17 T 06-07-2017 CAK77_RS12730 ea5b2a91e805b0059e09acafc6adff32 224 SUPERFAMILY SSF55785 31 134 3.84E-14 T 06-07-2017 IPR000014 PAS domain CAK77_RS12730 ea5b2a91e805b0059e09acafc6adff32 224 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 45 135 8.3E-7 T 06-07-2017 IPR000014 PAS domain CAK77_RS16650 b01d150334aba9eb60dbf2cda3b70909 288 Gene3D G3DSA:2.40.10.10 147 231 1.6E-6 T 06-07-2017 CAK77_RS16650 b01d150334aba9eb60dbf2cda3b70909 288 Gene3D G3DSA:2.40.10.10 59 102 1.6E-6 T 06-07-2017 CAK77_RS16650 b01d150334aba9eb60dbf2cda3b70909 288 SUPERFAMILY SSF50494 48 229 7.81E-18 T 06-07-2017 IPR009003 Peptidase S1, PA clan CAK77_RS03180 eeb1e4ad145ee67e928fa5c8c8aa9e3f 353 Gene3D G3DSA:1.10.540.10 1 113 5.9E-14 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS03180 eeb1e4ad145ee67e928fa5c8c8aa9e3f 353 SUPERFAMILY SSF47203 217 348 3.87E-23 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS03180 eeb1e4ad145ee67e928fa5c8c8aa9e3f 353 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 112 5.5E-10 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS03180 eeb1e4ad145ee67e928fa5c8c8aa9e3f 353 Gene3D G3DSA:1.20.140.10 219 344 9.5E-22 T 06-07-2017 CAK77_RS03180 eeb1e4ad145ee67e928fa5c8c8aa9e3f 353 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 220 344 2.0E-15 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS03180 eeb1e4ad145ee67e928fa5c8c8aa9e3f 353 Gene3D G3DSA:2.40.110.10 127 206 1.1E-8 T 06-07-2017 CAK77_RS03180 eeb1e4ad145ee67e928fa5c8c8aa9e3f 353 SUPERFAMILY SSF56645 1 206 1.96E-30 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK77_RS13575 d9a00b18967f60d7aa9ef585f32c2a46 261 SUPERFAMILY SSF51351 1 251 1.23E-87 T 06-07-2017 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK77_RS13575 d9a00b18967f60d7aa9ef585f32c2a46 261 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 3 255 39.123 T 06-07-2017 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK77_RS13575 d9a00b18967f60d7aa9ef585f32c2a46 261 Gene3D G3DSA:3.20.20.70 3 252 5.4E-101 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK77_RS13575 d9a00b18967f60d7aa9ef585f32c2a46 261 ProSitePatterns PS00171 Triosephosphate isomerase active site. 170 180 - T 06-07-2017 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK77_RS13575 d9a00b18967f60d7aa9ef585f32c2a46 261 Pfam PF00121 Triosephosphate isomerase 6 251 1.1E-85 T 06-07-2017 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK77_RS13575 d9a00b18967f60d7aa9ef585f32c2a46 261 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 6 244 8.0E-57 T 06-07-2017 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK77_RS05655 179388db60ca1f1c4e9b3bc2811d8845 196 Pfam PF01195 Peptidyl-tRNA hydrolase 10 191 2.4E-53 T 06-07-2017 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CAK77_RS05655 179388db60ca1f1c4e9b3bc2811d8845 196 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 115 125 - T 06-07-2017 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 CAK77_RS05655 179388db60ca1f1c4e9b3bc2811d8845 196 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 8 186 33.523 T 06-07-2017 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CAK77_RS05655 179388db60ca1f1c4e9b3bc2811d8845 196 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 21 34 - T 06-07-2017 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 CAK77_RS05655 179388db60ca1f1c4e9b3bc2811d8845 196 SUPERFAMILY SSF53178 9 194 4.32E-63 T 06-07-2017 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CAK77_RS05655 179388db60ca1f1c4e9b3bc2811d8845 196 Gene3D G3DSA:3.40.50.1470 8 194 1.1E-69 T 06-07-2017 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CAK77_RS05655 179388db60ca1f1c4e9b3bc2811d8845 196 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 10 193 5.1E-56 T 06-07-2017 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CAK77_RS18220 19f2c7f18b35fb787fb64a2cb56f908f 394 SUPERFAMILY SSF53187 302 387 1.13E-72 T 06-07-2017 CAK77_RS18220 19f2c7f18b35fb787fb64a2cb56f908f 394 SUPERFAMILY SSF53187 11 201 1.13E-72 T 06-07-2017 CAK77_RS18220 19f2c7f18b35fb787fb64a2cb56f908f 394 Gene3D G3DSA:3.40.630.10 302 387 1.5E-88 T 06-07-2017 CAK77_RS18220 19f2c7f18b35fb787fb64a2cb56f908f 394 Gene3D G3DSA:3.40.630.10 4 182 1.5E-88 T 06-07-2017 CAK77_RS18220 19f2c7f18b35fb787fb64a2cb56f908f 394 Pfam PF01546 Peptidase family M20/M25/M40 77 386 2.2E-28 T 06-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CAK77_RS18220 19f2c7f18b35fb787fb64a2cb56f908f 394 Gene3D G3DSA:3.30.70.360 186 301 3.3E-26 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAK77_RS18220 19f2c7f18b35fb787fb64a2cb56f908f 394 PIRSF PIRSF005962 6 391 1.9E-99 T 06-07-2017 IPR017439 Amidohydrolase GO:0016787 CAK77_RS18220 19f2c7f18b35fb787fb64a2cb56f908f 394 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 20 377 4.4E-98 T 06-07-2017 IPR017439 Amidohydrolase GO:0016787 CAK77_RS18220 19f2c7f18b35fb787fb64a2cb56f908f 394 SUPERFAMILY SSF55031 186 303 3.44E-18 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAK77_RS22145 8efc2a7f3791222b68a341e501d76ca2 149 Pfam PF13238 AAA domain 4 109 7.7E-13 T 06-07-2017 CAK77_RS22145 8efc2a7f3791222b68a341e501d76ca2 149 SUPERFAMILY SSF52540 3 145 1.81E-15 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS22145 8efc2a7f3791222b68a341e501d76ca2 149 Gene3D G3DSA:3.40.50.300 3 147 3.5E-13 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS08265 eaed4910074a1c98c04124be01f405bc 473 PIRSF PIRSF010256 2 473 2.2E-120 T 06-07-2017 IPR011195 Uncharacterised conserved protein UCP010256 CAK77_RS08265 eaed4910074a1c98c04124be01f405bc 473 SUPERFAMILY SSF53300 302 432 2.08E-7 T 06-07-2017 IPR002035 von Willebrand factor, type A CAK77_RS08265 eaed4910074a1c98c04124be01f405bc 473 Pfam PF05762 VWA domain containing CoxE-like protein 248 466 2.7E-57 T 06-07-2017 IPR008912 Uncharacterised protein family CoxE-like CAK77_RS09660 ada373404712aacc3de61b2bc4cedbae 462 Pfam PF01474 Class-II DAHP synthetase family 31 457 2.0E-186 T 06-07-2017 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 CAK77_RS09660 ada373404712aacc3de61b2bc4cedbae 462 SUPERFAMILY SSF51569 5 461 3.52E-190 T 06-07-2017 CAK77_RS09660 ada373404712aacc3de61b2bc4cedbae 462 TIGRFAM TIGR01358 DAHP_synth_II: 3-deoxy-7-phosphoheptulonate synthase 26 462 1.6E-216 T 06-07-2017 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 CAK77_RS06120 02478145e419c84312ef10deda06a186 250 SUPERFAMILY SSF51735 5 248 7.61E-78 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS06120 02478145e419c84312ef10deda06a186 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.6E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06120 02478145e419c84312ef10deda06a186 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 1.6E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06120 02478145e419c84312ef10deda06a186 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 1.6E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06120 02478145e419c84312ef10deda06a186 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 1.6E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06120 02478145e419c84312ef10deda06a186 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 1.6E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06120 02478145e419c84312ef10deda06a186 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 1.6E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06120 02478145e419c84312ef10deda06a186 250 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 245 2.0E-62 T 06-07-2017 CAK77_RS06120 02478145e419c84312ef10deda06a186 250 Gene3D G3DSA:3.40.50.720 2 248 1.3E-78 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS06120 02478145e419c84312ef10deda06a186 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 8.1E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06120 02478145e419c84312ef10deda06a186 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 8.1E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06120 02478145e419c84312ef10deda06a186 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 8.1E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS08485 1e15a740ae0ce39178f17e7069300fc8 341 PIRSF PIRSF005485 1 341 3.4E-101 T 06-07-2017 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 CAK77_RS08485 1e15a740ae0ce39178f17e7069300fc8 341 SUPERFAMILY SSF46785 5 84 1.4E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS08485 1e15a740ae0ce39178f17e7069300fc8 341 Gene3D G3DSA:1.10.10.10 3 86 2.5E-33 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS08485 1e15a740ae0ce39178f17e7069300fc8 341 TIGRFAM TIGR00331 hrcA: heat-inducible transcription repressor HrcA 5 336 2.9E-88 T 06-07-2017 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 CAK77_RS08485 1e15a740ae0ce39178f17e7069300fc8 341 Gene3D G3DSA:3.30.450.40 179 340 5.7E-36 T 06-07-2017 IPR029016 GAF domain-like CAK77_RS08485 1e15a740ae0ce39178f17e7069300fc8 341 SUPERFAMILY SSF55781 73 340 1.28E-52 T 06-07-2017 IPR029016 GAF domain-like CAK77_RS08485 1e15a740ae0ce39178f17e7069300fc8 341 Hamap MF_00081 Heat-inducible transcription repressor HrcA [hrcA]. 3 331 26.806 T 06-07-2017 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 CAK77_RS08485 1e15a740ae0ce39178f17e7069300fc8 341 Pfam PF01628 HrcA protein C terminal domain 105 324 1.6E-61 T 06-07-2017 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 CAK77_RS20840 67e902bb120ba965982ba13012a930f3 392 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 122 1.6E-23 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS20840 67e902bb120ba965982ba13012a930f3 392 Gene3D G3DSA:2.40.110.10 126 221 6.8E-31 T 06-07-2017 CAK77_RS20840 67e902bb120ba965982ba13012a930f3 392 SUPERFAMILY SSF47203 231 388 6.12E-24 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS20840 67e902bb120ba965982ba13012a930f3 392 SUPERFAMILY SSF56645 3 244 2.23E-65 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK77_RS20840 67e902bb120ba965982ba13012a930f3 392 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 127 212 1.1E-19 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAK77_RS20840 67e902bb120ba965982ba13012a930f3 392 Gene3D G3DSA:1.10.540.10 4 122 3.9E-29 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS20840 67e902bb120ba965982ba13012a930f3 392 Gene3D G3DSA:1.20.140.10 222 389 2.0E-36 T 06-07-2017 CAK77_RS20840 67e902bb120ba965982ba13012a930f3 392 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 231 384 4.4E-38 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS05505 7e8697ab56dabae041a34dfc7f508048 330 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 88 5.6E-8 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAK77_RS05505 7e8697ab56dabae041a34dfc7f508048 330 SUPERFAMILY SSF50129 1 140 1.32E-35 T 06-07-2017 IPR011032 GroES-like CAK77_RS05505 7e8697ab56dabae041a34dfc7f508048 330 Pfam PF00107 Zinc-binding dehydrogenase 152 265 1.5E-20 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAK77_RS05505 7e8697ab56dabae041a34dfc7f508048 330 SUPERFAMILY SSF51735 112 268 1.47E-37 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS05505 7e8697ab56dabae041a34dfc7f508048 330 TIGRFAM TIGR02824 quinone_pig3: putative NAD(P)H quinone oxidoreductase, PIG3 family 1 327 4.3E-129 T 06-07-2017 IPR014189 Quinone oxidoreductase PIG3 Reactome: R-HSA-6803205 CAK77_RS05505 7e8697ab56dabae041a34dfc7f508048 330 SMART SM00829 10 325 2.9E-31 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAK77_RS05505 7e8697ab56dabae041a34dfc7f508048 330 Gene3D G3DSA:3.40.50.720 147 258 8.9E-23 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS05505 7e8697ab56dabae041a34dfc7f508048 330 Gene3D G3DSA:3.90.180.10 1 146 3.8E-42 T 06-07-2017 IPR011032 GroES-like CAK77_RS17835 eda0d7534fa5ccdab3c52930daa8a6c3 649 Pfam PF01756 Acyl-CoA oxidase 508 641 2.9E-23 T 06-07-2017 IPR002655 Acyl-CoA oxidase, C-terminal GO:0003997|GO:0005777|GO:0006635|GO:0055114 KEGG: 00071+1.3.3.6|KEGG: 00592+1.3.3.6|MetaCyc: PWY-5136|MetaCyc: PWY-6837|MetaCyc: PWY-6920|MetaCyc: PWY-7007|MetaCyc: PWY-7288|MetaCyc: PWY-7291|MetaCyc: PWY-7337|MetaCyc: PWY-7338|MetaCyc: PWY-7340|MetaCyc: PWY-735|MetaCyc: PWY-7606|MetaCyc: PWY-7726 CAK77_RS17835 eda0d7534fa5ccdab3c52930daa8a6c3 649 SUPERFAMILY SSF47203 500 642 3.24E-37 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS17835 eda0d7534fa5ccdab3c52930daa8a6c3 649 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 287 447 6.7E-13 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS17835 eda0d7534fa5ccdab3c52930daa8a6c3 649 Gene3D G3DSA:1.20.140.10 506 635 1.0E-36 T 06-07-2017 CAK77_RS17835 eda0d7534fa5ccdab3c52930daa8a6c3 649 SUPERFAMILY SSF47203 283 467 3.22E-49 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS17835 eda0d7534fa5ccdab3c52930daa8a6c3 649 PIRSF PIRSF000168 35 648 1.8E-173 T 06-07-2017 IPR012258 Acyl-CoA oxidase GO:0003997|GO:0005777|GO:0006631|GO:0050660|GO:0055114 KEGG: 00071+1.3.3.6|KEGG: 00592+1.3.3.6|MetaCyc: PWY-5136|MetaCyc: PWY-6837|MetaCyc: PWY-6920|MetaCyc: PWY-7007|MetaCyc: PWY-7288|MetaCyc: PWY-7291|MetaCyc: PWY-7337|MetaCyc: PWY-7338|MetaCyc: PWY-7340|MetaCyc: PWY-735|MetaCyc: PWY-7606|MetaCyc: PWY-7726 CAK77_RS17835 eda0d7534fa5ccdab3c52930daa8a6c3 649 Gene3D G3DSA:1.10.540.10 50 135 6.7E-8 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS17835 eda0d7534fa5ccdab3c52930daa8a6c3 649 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 139 253 5.2E-16 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAK77_RS17835 eda0d7534fa5ccdab3c52930daa8a6c3 649 Gene3D G3DSA:1.20.140.10 294 454 1.7E-52 T 06-07-2017 CAK77_RS17835 eda0d7534fa5ccdab3c52930daa8a6c3 649 SUPERFAMILY SSF56645 18 269 6.94E-49 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK77_RS17835 eda0d7534fa5ccdab3c52930daa8a6c3 649 Gene3D G3DSA:2.40.110.10 138 273 6.0E-40 T 06-07-2017 CAK77_RS17835 eda0d7534fa5ccdab3c52930daa8a6c3 649 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 28 133 1.8E-6 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS23405 b9ba2231b664a69a10977b228d4a0c62 255 SUPERFAMILY SSF53335 58 231 2.34E-20 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS23405 b9ba2231b664a69a10977b228d4a0c62 255 Pfam PF13649 Methyltransferase domain 83 176 7.2E-11 T 06-07-2017 CAK77_RS23405 b9ba2231b664a69a10977b228d4a0c62 255 Gene3D G3DSA:3.40.50.150 82 230 3.9E-16 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS17930 5b1b08182f0cd01b4a6c9fd06245c070 137 Pfam PF12005 Protein of unknown function (DUF3499) 5 134 1.6E-48 T 06-07-2017 IPR021888 Protein of unknown function DUF3499 CAK77_RS16940 defeb8021092221076f719cad2df723a 399 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 6 322 3.0E-62 T 06-07-2017 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 CAK77_RS16940 defeb8021092221076f719cad2df723a 399 SUPERFAMILY SSF51905 285 392 1.11E-49 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS16940 defeb8021092221076f719cad2df723a 399 SUPERFAMILY SSF51905 3 179 1.11E-49 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS16940 defeb8021092221076f719cad2df723a 399 Pfam PF01494 FAD binding domain 6 328 2.1E-23 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 CAK77_RS16940 defeb8021092221076f719cad2df723a 399 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 152 167 1.3E-9 T 06-07-2017 CAK77_RS16940 defeb8021092221076f719cad2df723a 399 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 303 319 1.3E-9 T 06-07-2017 CAK77_RS16940 defeb8021092221076f719cad2df723a 399 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 1.3E-9 T 06-07-2017 CAK77_RS16940 defeb8021092221076f719cad2df723a 399 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 288 303 1.3E-9 T 06-07-2017 CAK77_RS16940 defeb8021092221076f719cad2df723a 399 Gene3D G3DSA:3.30.9.10 165 330 1.1E-35 T 06-07-2017 CAK77_RS16940 defeb8021092221076f719cad2df723a 399 Gene3D G3DSA:3.50.50.60 3 164 1.0E-24 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS23630 179464076c4a73bce59ce7d0721ca46d 389 SUPERFAMILY SSF51905 117 254 4.83E-27 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS23630 179464076c4a73bce59ce7d0721ca46d 389 SUPERFAMILY SSF51905 213 321 4.32E-23 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS23630 179464076c4a73bce59ce7d0721ca46d 389 SUPERFAMILY SSF51905 3 117 4.32E-23 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS23630 179464076c4a73bce59ce7d0721ca46d 389 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 195 301 8.5E-8 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS23630 179464076c4a73bce59ce7d0721ca46d 389 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 125 3.5E-14 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS23630 179464076c4a73bce59ce7d0721ca46d 389 Gene3D G3DSA:3.50.50.60 197 317 3.1E-17 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS23630 179464076c4a73bce59ce7d0721ca46d 389 Gene3D G3DSA:3.50.50.60 1 125 4.8E-24 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS23630 179464076c4a73bce59ce7d0721ca46d 389 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 1.3E-6 T 06-07-2017 CAK77_RS23630 179464076c4a73bce59ce7d0721ca46d 389 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 99 117 1.3E-6 T 06-07-2017 CAK77_RS23630 179464076c4a73bce59ce7d0721ca46d 389 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 266 288 1.3E-6 T 06-07-2017 CAK77_RS11595 dd373e73fb0b58135275a0815d959e94 171 Gene3D G3DSA:3.10.180.10 13 152 3.6E-16 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK77_RS11595 dd373e73fb0b58135275a0815d959e94 171 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 17 139 4.8E-26 T 06-07-2017 CAK77_RS11595 dd373e73fb0b58135275a0815d959e94 171 SUPERFAMILY SSF54593 12 145 1.2E-17 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK77_RS10715 815c16ced70a51a4c530f2f95783debd 386 Gene3D G3DSA:3.90.480.10 235 307 6.0E-21 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAK77_RS10715 815c16ced70a51a4c530f2f95783debd 386 Gene3D G3DSA:3.90.480.10 18 86 6.0E-21 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAK77_RS10715 815c16ced70a51a4c530f2f95783debd 386 SUPERFAMILY SSF55124 177 306 1.4E-19 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAK77_RS10715 815c16ced70a51a4c530f2f95783debd 386 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 24 72 4.5E-10 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAK77_RS10715 815c16ced70a51a4c530f2f95783debd 386 SUPERFAMILY SSF55124 6 83 5.4E-17 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAK77_RS10715 815c16ced70a51a4c530f2f95783debd 386 TIGRFAM TIGR02435 CobG: precorrin-3B synthase 7 379 2.7E-79 T 06-07-2017 IPR012798 Cobalamin (vitamin B12) biosynthesis CobG-like CAK77_RS10715 815c16ced70a51a4c530f2f95783debd 386 SUPERFAMILY SSF56014 91 183 3.49E-6 T 06-07-2017 CAK77_RS03030 d52df1a2a87d55294751fae04688e672 400 Gene3D G3DSA:2.40.110.10 129 207 9.9E-27 T 06-07-2017 CAK77_RS03030 d52df1a2a87d55294751fae04688e672 400 Gene3D G3DSA:1.20.140.10 208 396 1.2E-46 T 06-07-2017 CAK77_RS03030 d52df1a2a87d55294751fae04688e672 400 Gene3D G3DSA:1.10.540.10 6 116 1.7E-41 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS03030 d52df1a2a87d55294751fae04688e672 400 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 246 378 4.0E-37 T 06-07-2017 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain CAK77_RS03030 d52df1a2a87d55294751fae04688e672 400 SUPERFAMILY SSF56645 4 214 5.37E-35 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK77_RS03030 d52df1a2a87d55294751fae04688e672 400 SUPERFAMILY SSF47203 237 384 9.33E-12 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS03030 d52df1a2a87d55294751fae04688e672 400 PIRSF PIRSF016578 1 400 5.3E-135 T 06-07-2017 CAK77_RS07400 1a9e30b516a28f701f1c1b9716c44dc5 652 SMART SM00491 476 605 5.0E-40 T 06-07-2017 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 CAK77_RS07400 1a9e30b516a28f701f1c1b9716c44dc5 652 SUPERFAMILY SSF52540 376 390 2.61E-17 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS07400 1a9e30b516a28f701f1c1b9716c44dc5 652 SUPERFAMILY SSF52540 164 235 2.61E-17 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS07400 1a9e30b516a28f701f1c1b9716c44dc5 652 SUPERFAMILY SSF52540 8 62 2.61E-17 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS07400 1a9e30b516a28f701f1c1b9716c44dc5 652 SUPERFAMILY SSF52540 433 594 2.61E-17 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS07400 1a9e30b516a28f701f1c1b9716c44dc5 652 Pfam PF00270 DEAD/DEAH box helicase 8 59 2.5E-5 T 06-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CAK77_RS07400 1a9e30b516a28f701f1c1b9716c44dc5 652 Pfam PF13307 Helicase C-terminal domain 459 617 3.7E-26 T 06-07-2017 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 CAK77_RS07400 1a9e30b516a28f701f1c1b9716c44dc5 652 SMART SM00487 2 283 0.0074 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain CAK77_RS07400 1a9e30b516a28f701f1c1b9716c44dc5 652 Gene3D G3DSA:3.40.50.300 164 231 1.0E-20 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS07400 1a9e30b516a28f701f1c1b9716c44dc5 652 Gene3D G3DSA:3.40.50.300 378 386 1.0E-20 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS07400 1a9e30b516a28f701f1c1b9716c44dc5 652 Gene3D G3DSA:3.40.50.300 9 74 1.0E-20 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS14285 e55281cb43ee6ec1eaa2360386545ef9 242 Gene3D G3DSA:2.60.40.1650 38 106 4.2E-21 T 06-07-2017 CAK77_RS14285 e55281cb43ee6ec1eaa2360386545ef9 242 Gene3D G3DSA:2.60.40.1650 180 242 4.2E-21 T 06-07-2017 CAK77_RS14285 e55281cb43ee6ec1eaa2360386545ef9 242 SUPERFAMILY SSF56959 37 239 2.09E-5 T 06-07-2017 IPR016183 Leukocidin/porin GO:0005576|GO:0051715 CAK77_RS14285 e55281cb43ee6ec1eaa2360386545ef9 242 Pfam PF09203 MspA 46 240 2.2E-41 T 06-07-2017 IPR015286 Porin family, mycobacterial-type CAK77_RS14975 17ec6a59f2ee80acc4a4d7df76e23373 267 Pfam PF00480 ROK family 23 180 3.2E-17 T 06-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 CAK77_RS14975 17ec6a59f2ee80acc4a4d7df76e23373 267 Gene3D G3DSA:3.30.420.40 125 262 6.5E-33 T 06-07-2017 CAK77_RS14975 17ec6a59f2ee80acc4a4d7df76e23373 267 SUPERFAMILY SSF53067 23 262 2.96E-33 T 06-07-2017 CAK77_RS14975 17ec6a59f2ee80acc4a4d7df76e23373 267 Gene3D G3DSA:3.30.420.40 16 124 6.4E-40 T 06-07-2017 CAK77_RS10250 c3d51281c1f27d4e396c8713467e9c29 230 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 199 6.0E-45 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 CAK77_RS10250 c3d51281c1f27d4e396c8713467e9c29 230 Gene3D G3DSA:3.40.50.1240 1 200 2.8E-41 T 06-07-2017 IPR029033 Histidine phosphatase superfamily CAK77_RS10250 c3d51281c1f27d4e396c8713467e9c29 230 SUPERFAMILY SSF53254 1 201 2.14E-41 T 06-07-2017 IPR029033 Histidine phosphatase superfamily CAK77_RS10250 c3d51281c1f27d4e396c8713467e9c29 230 TIGRFAM TIGR03848 MSMEG_4193: probable phosphomutase, MSMEG_4193 family 2 205 8.3E-100 T 06-07-2017 IPR022492 Phosphomutase MSMEG4193, putative CAK77_RS10250 c3d51281c1f27d4e396c8713467e9c29 230 SMART SM00855 2 160 1.3E-18 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 CAK77_RS01950 85dfbf7a2befcb8ccb049fd8b7137328 330 Pfam PF01944 Stage II sporulation protein M 111 281 6.6E-35 T 06-07-2017 IPR002798 Stage II sporulation protein M-like CAK77_RS21820 78adf3a13aa531e72e1ab7ece7c4b5ea 727 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 469 562 2.6E-18 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAK77_RS21820 78adf3a13aa531e72e1ab7ece7c4b5ea 727 SUPERFAMILY SSF56645 362 586 1.44E-56 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK77_RS21820 78adf3a13aa531e72e1ab7ece7c4b5ea 727 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 94 7.9E-11 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS21820 78adf3a13aa531e72e1ab7ece7c4b5ea 727 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 378 465 1.4E-10 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS21820 78adf3a13aa531e72e1ab7ece7c4b5ea 727 Gene3D G3DSA:1.10.540.10 3 91 2.6E-12 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS21820 78adf3a13aa531e72e1ab7ece7c4b5ea 727 Gene3D G3DSA:2.40.110.10 468 564 6.6E-31 T 06-07-2017 CAK77_RS21820 78adf3a13aa531e72e1ab7ece7c4b5ea 727 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 575 721 6.9E-16 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS21820 78adf3a13aa531e72e1ab7ece7c4b5ea 727 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 218 341 9.4E-25 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS21820 78adf3a13aa531e72e1ab7ece7c4b5ea 727 Gene3D G3DSA:1.20.140.10 218 343 2.0E-32 T 06-07-2017 CAK77_RS21820 78adf3a13aa531e72e1ab7ece7c4b5ea 727 Gene3D G3DSA:1.10.540.10 394 466 1.4E-10 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS21820 78adf3a13aa531e72e1ab7ece7c4b5ea 727 SUPERFAMILY SSF47203 216 345 8.86E-33 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS21820 78adf3a13aa531e72e1ab7ece7c4b5ea 727 SUPERFAMILY SSF56645 5 203 3.01E-22 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK77_RS21820 78adf3a13aa531e72e1ab7ece7c4b5ea 727 SUPERFAMILY SSF47203 575 723 6.6E-14 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS21820 78adf3a13aa531e72e1ab7ece7c4b5ea 727 Gene3D G3DSA:1.20.140.10 565 726 3.0E-26 T 06-07-2017 CAK77_RS17910 5c183a8f9044def4be9280a2ea6cc62e 307 Gene3D G3DSA:1.20.1510.10 7 216 1.6E-32 T 06-07-2017 IPR027469 Cation efflux protein transmembrane domain CAK77_RS17910 5c183a8f9044def4be9280a2ea6cc62e 307 SUPERFAMILY SSF161111 6 219 1.57E-36 T 06-07-2017 CAK77_RS17910 5c183a8f9044def4be9280a2ea6cc62e 307 Gene3D G3DSA:3.30.70.1350 221 298 1.8E-6 T 06-07-2017 IPR027470 Cation efflux protein, cytoplasmic domain CAK77_RS17910 5c183a8f9044def4be9280a2ea6cc62e 307 SUPERFAMILY SSF160240 226 294 1.83E-6 T 06-07-2017 CAK77_RS17910 5c183a8f9044def4be9280a2ea6cc62e 307 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 7 287 1.5E-38 T 06-07-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CAK77_RS17910 5c183a8f9044def4be9280a2ea6cc62e 307 Pfam PF01545 Cation efflux family 10 212 7.7E-32 T 06-07-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CAK77_RS04070 00b39fb21df6232036857c7fd86a4cdb 294 PIRSF PIRSF000105 7 294 1.1E-63 T 06-07-2017 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 CAK77_RS04070 00b39fb21df6232036857c7fd86a4cdb 294 SUPERFAMILY SSF51735 11 187 2.42E-33 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS04070 00b39fb21df6232036857c7fd86a4cdb 294 SUPERFAMILY SSF48179 191 286 2.3E-20 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAK77_RS04070 00b39fb21df6232036857c7fd86a4cdb 294 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 191 286 7.9E-19 T 06-07-2017 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 CAK77_RS04070 00b39fb21df6232036857c7fd86a4cdb 294 Gene3D G3DSA:1.10.1040.10 193 286 8.2E-20 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAK77_RS04070 00b39fb21df6232036857c7fd86a4cdb 294 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 14 173 7.8E-34 T 06-07-2017 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 CAK77_RS04070 00b39fb21df6232036857c7fd86a4cdb 294 Gene3D G3DSA:3.40.50.720 10 192 7.0E-33 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS16115 1b7671a4396b2f897542a34586507322 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 06-07-2017 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 CAK77_RS16115 1b7671a4396b2f897542a34586507322 112 PRINTS PR00340 P-II protein signature 2 17 2.8E-41 T 06-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CAK77_RS16115 1b7671a4396b2f897542a34586507322 112 PRINTS PR00340 P-II protein signature 52 75 2.8E-41 T 06-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CAK77_RS16115 1b7671a4396b2f897542a34586507322 112 PRINTS PR00340 P-II protein signature 23 41 2.8E-41 T 06-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CAK77_RS16115 1b7671a4396b2f897542a34586507322 112 PRINTS PR00340 P-II protein signature 83 103 2.8E-41 T 06-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CAK77_RS16115 1b7671a4396b2f897542a34586507322 112 Gene3D G3DSA:3.30.70.120 1 112 2.5E-48 T 06-07-2017 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal CAK77_RS16115 1b7671a4396b2f897542a34586507322 112 PIRSF PIRSF039144 1 112 1.0E-53 T 06-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CAK77_RS16115 1b7671a4396b2f897542a34586507322 112 SUPERFAMILY SSF54913 1 112 3.81E-44 T 06-07-2017 IPR011322 Nitrogen regulatory PII-like, alpha/beta CAK77_RS16115 1b7671a4396b2f897542a34586507322 112 SMART SM00938 4 105 4.9E-61 T 06-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CAK77_RS16115 1b7671a4396b2f897542a34586507322 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 06-07-2017 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 CAK77_RS16115 1b7671a4396b2f897542a34586507322 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 1.5E-41 T 06-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CAK77_RS10425 7c6f97aba425affc6b240b8a213f0c63 99 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 1 99 19.267 T 06-07-2017 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 CAK77_RS10425 7c6f97aba425affc6b240b8a213f0c63 99 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 6 93 4.7E-22 T 06-07-2017 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 CAK77_RS02930 0c4664809a9fa142897e2abcbaa4f0a2 473 Pfam PF13481 AAA domain 78 220 7.8E-15 T 06-07-2017 CAK77_RS02930 0c4664809a9fa142897e2abcbaa4f0a2 473 Hamap MF_01498 DNA repair protein RadA [radA]. 21 452 41.202 T 06-07-2017 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 CAK77_RS02930 0c4664809a9fa142897e2abcbaa4f0a2 473 SUPERFAMILY SSF54211 301 451 1.29E-28 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAK77_RS02930 0c4664809a9fa142897e2abcbaa4f0a2 473 SUPERFAMILY SSF54211 253 267 1.29E-28 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAK77_RS02930 0c4664809a9fa142897e2abcbaa4f0a2 473 PRINTS PR01874 DNA repair protein radA signature 172 196 8.5E-79 T 06-07-2017 CAK77_RS02930 0c4664809a9fa142897e2abcbaa4f0a2 473 PRINTS PR01874 DNA repair protein radA signature 122 139 8.5E-79 T 06-07-2017 CAK77_RS02930 0c4664809a9fa142897e2abcbaa4f0a2 473 PRINTS PR01874 DNA repair protein radA signature 246 272 8.5E-79 T 06-07-2017 CAK77_RS02930 0c4664809a9fa142897e2abcbaa4f0a2 473 PRINTS PR01874 DNA repair protein radA signature 320 343 8.5E-79 T 06-07-2017 CAK77_RS02930 0c4664809a9fa142897e2abcbaa4f0a2 473 PRINTS PR01874 DNA repair protein radA signature 211 239 8.5E-79 T 06-07-2017 CAK77_RS02930 0c4664809a9fa142897e2abcbaa4f0a2 473 PRINTS PR01874 DNA repair protein radA signature 10 34 8.5E-79 T 06-07-2017 CAK77_RS02930 0c4664809a9fa142897e2abcbaa4f0a2 473 PRINTS PR01874 DNA repair protein radA signature 80 108 8.5E-79 T 06-07-2017 CAK77_RS02930 0c4664809a9fa142897e2abcbaa4f0a2 473 Gene3D G3DSA:3.40.50.300 62 275 1.1E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS02930 0c4664809a9fa142897e2abcbaa4f0a2 473 SMART SM00382 88 242 2.8E-6 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS02930 0c4664809a9fa142897e2abcbaa4f0a2 473 Gene3D G3DSA:3.30.230.10 282 451 4.8E-25 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CAK77_RS02930 0c4664809a9fa142897e2abcbaa4f0a2 473 TIGRFAM TIGR00416 sms: DNA repair protein RadA 1 447 4.0E-148 T 06-07-2017 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 CAK77_RS02930 0c4664809a9fa142897e2abcbaa4f0a2 473 SUPERFAMILY SSF52540 68 286 1.51E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS01315 4dc3ff1567afa52d1c9a10f105fdd452 411 Gene3D G3DSA:1.10.540.10 1 139 4.8E-33 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS01315 4dc3ff1567afa52d1c9a10f105fdd452 411 SUPERFAMILY SSF56645 2 267 1.05E-62 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK77_RS01315 4dc3ff1567afa52d1c9a10f105fdd452 411 Gene3D G3DSA:2.40.110.10 140 243 7.3E-36 T 06-07-2017 CAK77_RS01315 4dc3ff1567afa52d1c9a10f105fdd452 411 SUPERFAMILY SSF47203 253 408 1.61E-42 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS01315 4dc3ff1567afa52d1c9a10f105fdd452 411 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 10 137 2.2E-14 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS01315 4dc3ff1567afa52d1c9a10f105fdd452 411 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 141 241 2.4E-19 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAK77_RS01315 4dc3ff1567afa52d1c9a10f105fdd452 411 Gene3D G3DSA:1.20.140.10 244 409 6.0E-41 T 06-07-2017 CAK77_RS01315 4dc3ff1567afa52d1c9a10f105fdd452 411 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 254 402 2.9E-32 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS00535 c6e25532058926f6cf8a9b56168d61ef 299 SUPERFAMILY SSF54593 1 272 4.36E-41 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK77_RS00535 c6e25532058926f6cf8a9b56168d61ef 299 Gene3D G3DSA:3.10.180.10 134 296 1.3E-55 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK77_RS00535 c6e25532058926f6cf8a9b56168d61ef 299 Gene3D G3DSA:3.10.180.10 4 131 9.4E-31 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK77_RS00535 c6e25532058926f6cf8a9b56168d61ef 299 ProSitePatterns PS00934 Glyoxalase I signature 1. 144 165 - T 06-07-2017 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 CAK77_RS00535 c6e25532058926f6cf8a9b56168d61ef 299 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 141 263 8.9E-26 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CAK77_RS00535 c6e25532058926f6cf8a9b56168d61ef 299 TIGRFAM TIGR03213 23dbph12diox: 2,3-dihydroxybiphenyl 1,2-dioxygenase 3 290 3.5E-115 T 06-07-2017 IPR017626 2,3-dihydroxybiphenyl 1,2-dioxygenase GO:0005506|GO:0042178|GO:0051213|GO:0055114 CAK77_RS00535 c6e25532058926f6cf8a9b56168d61ef 299 ProSitePatterns PS00082 Extradiol ring-cleavage dioxygenases signature. 241 262 - T 06-07-2017 IPR000486 Extradiol ring-cleavage dioxygenase, class I /II GO:0003824|GO:0006725|GO:0008198|GO:0055114 CAK77_RS13565 96a640c6a3c287bfa01c9e95bdb6a159 382 Pfam PF04228 Putative neutral zinc metallopeptidase 181 336 9.2E-16 T 06-07-2017 IPR007343 Uncharacterised protein family, zinc metallopeptidase putative CAK77_RS07290 1a198dd5baaa4f5a5243b7177270eb1b 476 SUPERFAMILY SSF47917 358 472 1.94E-46 T 06-07-2017 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CAK77_RS07290 1a198dd5baaa4f5a5243b7177270eb1b 476 Gene3D G3DSA:1.10.1140.10 359 472 4.6E-46 T 06-07-2017 IPR024034 ATPase, F1 complex beta subunit/V1 complex, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CAK77_RS07290 1a198dd5baaa4f5a5243b7177270eb1b 476 Gene3D G3DSA:2.40.10.170 5 85 5.8E-28 T 06-07-2017 CAK77_RS07290 1a198dd5baaa4f5a5243b7177270eb1b 476 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 345 354 - T 06-07-2017 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CAK77_RS07290 1a198dd5baaa4f5a5243b7177270eb1b 476 SUPERFAMILY SSF50615 10 85 1.36E-22 T 06-07-2017 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CAK77_RS07290 1a198dd5baaa4f5a5243b7177270eb1b 476 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 10 472 1.0E-244 T 06-07-2017 IPR005722 ATPase, F1 complex, beta subunit GO:0015986|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201 CAK77_RS07290 1a198dd5baaa4f5a5243b7177270eb1b 476 SUPERFAMILY SSF52540 88 356 7.11E-85 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS07290 1a198dd5baaa4f5a5243b7177270eb1b 476 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 141 354 4.4E-63 T 06-07-2017 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CAK77_RS07290 1a198dd5baaa4f5a5243b7177270eb1b 476 Hamap MF_01347 ATP synthase subunit beta [atpB]. 8 472 53.868 T 06-07-2017 IPR005722 ATPase, F1 complex, beta subunit GO:0015986|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201 CAK77_RS07290 1a198dd5baaa4f5a5243b7177270eb1b 476 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 13 84 4.8E-20 T 06-07-2017 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CAK77_RS07290 1a198dd5baaa4f5a5243b7177270eb1b 476 Gene3D G3DSA:3.40.50.300 88 354 3.2E-100 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS07290 1a198dd5baaa4f5a5243b7177270eb1b 476 SMART SM00382 153 338 6.5E-8 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS05970 6142cb3adec339c38dc7bcf04611cca9 501 Gene3D G3DSA:3.40.309.10 264 446 3.4E-61 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAK77_RS05970 6142cb3adec339c38dc7bcf04611cca9 501 SUPERFAMILY SSF53720 4 485 5.5E-150 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAK77_RS05970 6142cb3adec339c38dc7bcf04611cca9 501 Gene3D G3DSA:3.40.605.10 7 263 4.4E-88 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAK77_RS05970 6142cb3adec339c38dc7bcf04611cca9 501 Pfam PF00171 Aldehyde dehydrogenase family 20 481 1.3E-138 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAK77_RS05970 6142cb3adec339c38dc7bcf04611cca9 501 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 8 485 5.3E-190 T 06-07-2017 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00410+1.2.1.18|KEGG: 00562+1.2.1.18|KEGG: 00640+1.2.1.18+1.2.1.27|MetaCyc: PWY-5642|MetaCyc: PWY-6373|Reactome: R-HSA-70895 CAK77_RS05970 6142cb3adec339c38dc7bcf04611cca9 501 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 277 288 - T 06-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CAK77_RS16705 1b13abc6a2e6d5ec252ec6f65ef60d9d 293 Pfam PF13444 Acetyltransferase (GNAT) domain 47 151 1.9E-29 T 06-07-2017 CAK77_RS16705 1b13abc6a2e6d5ec252ec6f65ef60d9d 293 SUPERFAMILY SSF55729 29 250 4.97E-38 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS16705 1b13abc6a2e6d5ec252ec6f65ef60d9d 293 Gene3D G3DSA:3.40.630.30 35 173 8.8E-30 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS24430 3ca49996c0ff406ae79c76f1b6f6dd20 468 Gene3D G3DSA:2.60.120.600 306 467 8.8E-53 T 06-07-2017 IPR010621 Domain of unknown function DUF1214 CAK77_RS24430 3ca49996c0ff406ae79c76f1b6f6dd20 468 SUPERFAMILY SSF160935 27 466 6.8E-130 T 06-07-2017 CAK77_RS24430 3ca49996c0ff406ae79c76f1b6f6dd20 468 Gene3D G3DSA:1.10.3360.10 203 296 1.7E-9 T 06-07-2017 IPR023289 VPA0735-like domain CAK77_RS24430 3ca49996c0ff406ae79c76f1b6f6dd20 468 Pfam PF06863 Protein of unknown function (DUF1254) 72 203 1.6E-42 T 06-07-2017 IPR010679 Domain of unknown function DUF1254 CAK77_RS24430 3ca49996c0ff406ae79c76f1b6f6dd20 468 Gene3D G3DSA:2.60.40.1610 84 202 3.4E-22 T 06-07-2017 IPR010679 Domain of unknown function DUF1254 CAK77_RS24430 3ca49996c0ff406ae79c76f1b6f6dd20 468 Pfam PF06742 Protein of unknown function (DUF1214) 342 453 2.6E-35 T 06-07-2017 IPR010621 Domain of unknown function DUF1214 CAK77_RS17345 3ca49996c0ff406ae79c76f1b6f6dd20 468 Gene3D G3DSA:2.60.120.600 306 467 8.8E-53 T 06-07-2017 IPR010621 Domain of unknown function DUF1214 CAK77_RS17345 3ca49996c0ff406ae79c76f1b6f6dd20 468 SUPERFAMILY SSF160935 27 466 6.8E-130 T 06-07-2017 CAK77_RS17345 3ca49996c0ff406ae79c76f1b6f6dd20 468 Gene3D G3DSA:1.10.3360.10 203 296 1.7E-9 T 06-07-2017 IPR023289 VPA0735-like domain CAK77_RS17345 3ca49996c0ff406ae79c76f1b6f6dd20 468 Pfam PF06863 Protein of unknown function (DUF1254) 72 203 1.6E-42 T 06-07-2017 IPR010679 Domain of unknown function DUF1254 CAK77_RS17345 3ca49996c0ff406ae79c76f1b6f6dd20 468 Gene3D G3DSA:2.60.40.1610 84 202 3.4E-22 T 06-07-2017 IPR010679 Domain of unknown function DUF1254 CAK77_RS17345 3ca49996c0ff406ae79c76f1b6f6dd20 468 Pfam PF06742 Protein of unknown function (DUF1214) 342 453 2.6E-35 T 06-07-2017 IPR010621 Domain of unknown function DUF1214 CAK77_RS20300 74e962dbc993540de2d2f735663c8023 674 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 131 149 7.4E-5 T 06-07-2017 CAK77_RS20300 74e962dbc993540de2d2f735663c8023 674 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 89 107 7.4E-5 T 06-07-2017 CAK77_RS20300 74e962dbc993540de2d2f735663c8023 674 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 7.4E-5 T 06-07-2017 CAK77_RS20300 74e962dbc993540de2d2f735663c8023 674 SUPERFAMILY SSF53474 390 658 2.05E-46 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS20300 74e962dbc993540de2d2f735663c8023 674 SUPERFAMILY SSF51905 1 178 2.33E-26 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS20300 74e962dbc993540de2d2f735663c8023 674 Pfam PF07859 alpha/beta hydrolase fold 437 638 5.1E-44 T 06-07-2017 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CAK77_RS20300 74e962dbc993540de2d2f735663c8023 674 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 144 4.9E-9 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS20300 74e962dbc993540de2d2f735663c8023 674 Gene3D G3DSA:3.40.50.1820 383 660 6.1E-57 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS20300 74e962dbc993540de2d2f735663c8023 674 Gene3D G3DSA:3.50.50.60 3 167 1.3E-24 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS01200 a61dde6ab85736850a68a6223b5f837c 328 SUPERFAMILY SSF50129 1 138 6.45E-36 T 06-07-2017 IPR011032 GroES-like CAK77_RS01200 a61dde6ab85736850a68a6223b5f837c 328 SUPERFAMILY SSF51735 113 271 2.1E-44 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS01200 a61dde6ab85736850a68a6223b5f837c 328 TIGRFAM TIGR02824 quinone_pig3: putative NAD(P)H quinone oxidoreductase, PIG3 family 1 327 3.3E-134 T 06-07-2017 IPR014189 Quinone oxidoreductase PIG3 Reactome: R-HSA-6803205 CAK77_RS01200 a61dde6ab85736850a68a6223b5f837c 328 Gene3D G3DSA:3.90.180.10 1 145 3.2E-48 T 06-07-2017 IPR011032 GroES-like CAK77_RS01200 a61dde6ab85736850a68a6223b5f837c 328 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 87 2.0E-7 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAK77_RS01200 a61dde6ab85736850a68a6223b5f837c 328 Gene3D G3DSA:3.40.50.720 146 259 4.8E-30 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS01200 a61dde6ab85736850a68a6223b5f837c 328 Pfam PF00107 Zinc-binding dehydrogenase 151 265 8.9E-27 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAK77_RS01200 a61dde6ab85736850a68a6223b5f837c 328 SMART SM00829 10 326 4.6E-40 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAK77_RS16875 0f505ca94dde46532e939441d79220be 157 Gene3D G3DSA:3.30.530.20 8 152 5.2E-5 T 06-07-2017 IPR023393 START-like domain CAK77_RS16875 0f505ca94dde46532e939441d79220be 157 SUPERFAMILY SSF55961 6 146 4.4E-11 T 06-07-2017 CAK77_RS16875 0f505ca94dde46532e939441d79220be 157 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 8 147 4.1E-8 T 06-07-2017 IPR019587 Polyketide cyclase/dehydrase CAK77_RS04845 3661df91e6a3d973105379152e6fb40b 503 Pfam PF00743 Flavin-binding monooxygenase-like 80 215 1.4E-12 T 06-07-2017 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 CAK77_RS04845 3661df91e6a3d973105379152e6fb40b 503 SUPERFAMILY SSF51905 1 386 3.19E-55 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS04845 3661df91e6a3d973105379152e6fb40b 503 Gene3D G3DSA:3.50.50.60 321 463 1.5E-6 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS04845 3661df91e6a3d973105379152e6fb40b 503 Gene3D G3DSA:3.50.50.60 2 215 3.5E-53 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS04845 3661df91e6a3d973105379152e6fb40b 503 Pfam PF13450 NAD(P)-binding Rossmann-like domain 9 56 4.6E-8 T 06-07-2017 CAK77_RS13600 d1fb51462e93752ac4d11e52b1c290ea 364 Hamap MF_00973 Gluconeogenesis factor. 14 325 31.402 T 06-07-2017 IPR010119 Gluconeogenesis factor CAK77_RS13600 d1fb51462e93752ac4d11e52b1c290ea 364 TIGRFAM TIGR01826 CofD_related: conserved hypothetical protein 18 322 5.9E-95 T 06-07-2017 IPR010119 Gluconeogenesis factor CAK77_RS13600 d1fb51462e93752ac4d11e52b1c290ea 364 Pfam PF01933 Uncharacterised protein family UPF0052 18 276 3.9E-67 T 06-07-2017 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 CAK77_RS13600 d1fb51462e93752ac4d11e52b1c290ea 364 SUPERFAMILY SSF142338 15 320 1.7E-82 T 06-07-2017 CAK77_RS13600 d1fb51462e93752ac4d11e52b1c290ea 364 Gene3D G3DSA:3.40.50.10680 92 321 1.5E-38 T 06-07-2017 CAK77_RS12550 c573737815f31181eac52d34b0c53f8d 139 SUPERFAMILY SSF52788 5 127 3.27E-33 T 06-07-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily CAK77_RS12550 c573737815f31181eac52d34b0c53f8d 139 Gene3D G3DSA:3.40.50.270 4 128 1.3E-37 T 06-07-2017 CAK77_RS12550 c573737815f31181eac52d34b0c53f8d 139 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 7 128 3.7E-21 T 06-07-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily CAK77_RS12550 c573737815f31181eac52d34b0c53f8d 139 SMART SM00226 5 130 7.1E-37 T 06-07-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily CAK77_RS10145 65cbf05fe2f3b78e7314fc0b6eaada94 319 Gene3D G3DSA:1.10.260.40 132 162 6.6E-4 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK77_RS10085 4ab4a640d446670a3fcd0d46c851b0cd 485 PRINTS PR00385 P450 superfamily signature 297 314 1.4E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS10085 4ab4a640d446670a3fcd0d46c851b0cd 485 PRINTS PR00385 P450 superfamily signature 424 433 1.4E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS10085 4ab4a640d446670a3fcd0d46c851b0cd 485 PRINTS PR00385 P450 superfamily signature 348 359 1.4E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS10085 4ab4a640d446670a3fcd0d46c851b0cd 485 PRINTS PR00385 P450 superfamily signature 433 444 1.4E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS10085 4ab4a640d446670a3fcd0d46c851b0cd 485 SUPERFAMILY SSF48264 53 485 6.94E-97 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS10085 4ab4a640d446670a3fcd0d46c851b0cd 485 Gene3D G3DSA:1.10.630.10 55 485 1.5E-97 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS10085 4ab4a640d446670a3fcd0d46c851b0cd 485 Pfam PF00067 Cytochrome P450 60 460 3.0E-68 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS10085 4ab4a640d446670a3fcd0d46c851b0cd 485 PRINTS PR00465 E-class P450 group IV signature 343 359 1.7E-20 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS10085 4ab4a640d446670a3fcd0d46c851b0cd 485 PRINTS PR00465 E-class P450 group IV signature 392 410 1.7E-20 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS10085 4ab4a640d446670a3fcd0d46c851b0cd 485 PRINTS PR00465 E-class P450 group IV signature 433 451 1.7E-20 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS10085 4ab4a640d446670a3fcd0d46c851b0cd 485 PRINTS PR00465 E-class P450 group IV signature 288 314 1.7E-20 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS10085 4ab4a640d446670a3fcd0d46c851b0cd 485 PRINTS PR00465 E-class P450 group IV signature 376 390 1.7E-20 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS10085 4ab4a640d446670a3fcd0d46c851b0cd 485 PRINTS PR00465 E-class P450 group IV signature 417 433 1.7E-20 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS10085 4ab4a640d446670a3fcd0d46c851b0cd 485 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 426 435 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CAK77_RS06610 366d87987fea93348ccc94803d6cc516 881 TIGRFAM TIGR03550 F420_cofG: 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofG subunit 107 437 6.6E-147 T 06-07-2017 IPR019939 CofG family GO:0009108|GO:0016765|GO:0051539 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 CAK77_RS06610 366d87987fea93348ccc94803d6cc516 881 Hamap MF_01612 FO synthase subunit 2 [cofH]. 519 878 49.814 T 06-07-2017 IPR019940 CofH family GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 CAK77_RS06610 366d87987fea93348ccc94803d6cc516 881 SUPERFAMILY SSF102114 109 413 4.58E-37 T 06-07-2017 CAK77_RS06610 366d87987fea93348ccc94803d6cc516 881 Hamap MF_01611 FO synthase subunit 1 [cofG]. 106 438 51.134 T 06-07-2017 IPR019939 CofG family GO:0009108|GO:0016765|GO:0051539 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 CAK77_RS06610 366d87987fea93348ccc94803d6cc516 881 Pfam PF04055 Radical SAM superfamily 114 297 4.5E-11 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 CAK77_RS06610 366d87987fea93348ccc94803d6cc516 881 Pfam PF04055 Radical SAM superfamily 575 747 2.3E-13 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 CAK77_RS06610 366d87987fea93348ccc94803d6cc516 881 Gene3D G3DSA:3.20.20.70 61 399 1.2E-71 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK77_RS06610 366d87987fea93348ccc94803d6cc516 881 Gene3D G3DSA:3.20.20.70 533 866 6.1E-72 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK77_RS06610 366d87987fea93348ccc94803d6cc516 881 TIGRFAM TIGR03551 F420_cofH: 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofH subunit 533 875 1.4E-159 T 06-07-2017 IPR019940 CofH family GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 CAK77_RS06610 366d87987fea93348ccc94803d6cc516 881 TIGRFAM TIGR00423 TIGR00423: radical SAM domain protein, CofH subfamily 567 874 3.9E-112 T 06-07-2017 IPR020050 FO synthase, subunit 2 GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 CAK77_RS06610 366d87987fea93348ccc94803d6cc516 881 SMART SM00729 110 342 9.3E-4 T 06-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CAK77_RS06610 366d87987fea93348ccc94803d6cc516 881 SUPERFAMILY SSF102114 531 841 5.36E-47 T 06-07-2017 CAK77_RS08365 26029c643a87557c7b2beb6e984e582c 622 SUPERFAMILY SSF50447 180 302 2.02E-24 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain CAK77_RS08365 26029c643a87557c7b2beb6e984e582c 622 Gene3D G3DSA:3.30.70.240 419 508 2.7E-20 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain CAK77_RS08365 26029c643a87557c7b2beb6e984e582c 622 SUPERFAMILY SSF52540 9 218 3.43E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS08365 26029c643a87557c7b2beb6e984e582c 622 SUPERFAMILY SSF54980 417 512 2.06E-22 T 06-07-2017 IPR009022 Elongation factor G, III-V domain CAK77_RS08365 26029c643a87557c7b2beb6e984e582c 622 PRINTS PR00315 GTP-binding elongation factor signature 60 68 3.6E-13 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAK77_RS08365 26029c643a87557c7b2beb6e984e582c 622 PRINTS PR00315 GTP-binding elongation factor signature 89 99 3.6E-13 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAK77_RS08365 26029c643a87557c7b2beb6e984e582c 622 PRINTS PR00315 GTP-binding elongation factor signature 17 30 3.6E-13 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAK77_RS08365 26029c643a87557c7b2beb6e984e582c 622 PRINTS PR00315 GTP-binding elongation factor signature 141 150 3.6E-13 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAK77_RS08365 26029c643a87557c7b2beb6e984e582c 622 PRINTS PR00315 GTP-binding elongation factor signature 105 116 3.6E-13 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAK77_RS08365 26029c643a87557c7b2beb6e984e582c 622 Pfam PF00679 Elongation factor G C-terminus 418 503 1.5E-20 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain CAK77_RS08365 26029c643a87557c7b2beb6e984e582c 622 Hamap MF_00071 Elongation factor 4 [lepA]. 1 616 282.441 T 06-07-2017 IPR006297 Elongation factor 4 GO:0005525 CAK77_RS08365 26029c643a87557c7b2beb6e984e582c 622 SMART SM00838 416 500 0.0018 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain CAK77_RS08365 26029c643a87557c7b2beb6e984e582c 622 Gene3D G3DSA:3.40.50.300 11 207 1.1E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS08365 26029c643a87557c7b2beb6e984e582c 622 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 53 68 - T 06-07-2017 IPR031157 Tr-type G domain, conserved site CAK77_RS08365 26029c643a87557c7b2beb6e984e582c 622 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 17 191 3.8E-17 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 CAK77_RS08365 26029c643a87557c7b2beb6e984e582c 622 Gene3D G3DSA:3.30.70.870 306 383 6.8E-26 T 06-07-2017 CAK77_RS08365 26029c643a87557c7b2beb6e984e582c 622 Gene3D G3DSA:2.40.30.10 208 304 2.4E-20 T 06-07-2017 CAK77_RS08365 26029c643a87557c7b2beb6e984e582c 622 SUPERFAMILY SSF54980 306 385 2.12E-19 T 06-07-2017 IPR009022 Elongation factor G, III-V domain CAK77_RS08365 26029c643a87557c7b2beb6e984e582c 622 Pfam PF00009 Elongation factor Tu GTP binding domain 15 196 1.6E-51 T 06-07-2017 CAK77_RS08365 26029c643a87557c7b2beb6e984e582c 622 TIGRFAM TIGR01393 lepA: elongation factor 4 15 613 1.1E-291 T 06-07-2017 IPR006297 Elongation factor 4 GO:0005525 CAK77_RS08365 26029c643a87557c7b2beb6e984e582c 622 Pfam PF06421 GTP-binding protein LepA C-terminus 507 611 3.3E-47 T 06-07-2017 IPR013842 GTP-binding protein LepA, C-terminal CAK77_RS15520 9bc66652a5954d9d8db51ba9ee603732 413 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 130 223 3.2E-22 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAK77_RS15520 9bc66652a5954d9d8db51ba9ee603732 413 Gene3D G3DSA:1.10.540.10 43 127 2.2E-10 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS15520 9bc66652a5954d9d8db51ba9ee603732 413 Gene3D G3DSA:2.40.110.10 129 225 6.4E-37 T 06-07-2017 CAK77_RS15520 9bc66652a5954d9d8db51ba9ee603732 413 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 236 393 2.8E-16 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS15520 9bc66652a5954d9d8db51ba9ee603732 413 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 26 126 7.4E-5 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS15520 9bc66652a5954d9d8db51ba9ee603732 413 SUPERFAMILY SSF47203 236 395 1.39E-14 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS15520 9bc66652a5954d9d8db51ba9ee603732 413 Gene3D G3DSA:1.20.140.10 226 400 6.7E-25 T 06-07-2017 CAK77_RS15520 9bc66652a5954d9d8db51ba9ee603732 413 SUPERFAMILY SSF56645 25 249 1.28E-62 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK77_RS03140 677f14f2d5e4c5678804381ed916aedf 252 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 249 6.0E-41 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAK77_RS03140 677f14f2d5e4c5678804381ed916aedf 252 SUPERFAMILY SSF52096 5 250 1.76E-61 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS03140 677f14f2d5e4c5678804381ed916aedf 252 Gene3D G3DSA:3.90.226.10 6 250 1.2E-59 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS21290 e52cd3732cd8a2f1dcab449b98f285a5 419 Pfam PF07158 Dicarboxylate carrier protein MatC N-terminus 4 147 1.6E-22 T 06-07-2017 IPR009827 Dicarboxylate carrier MatC N-terminal CAK77_RS14230 6fbf71773d6b7617e4a199be2a29aae5 341 SUPERFAMILY SSF48179 173 310 8.84E-24 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAK77_RS14230 6fbf71773d6b7617e4a199be2a29aae5 341 SUPERFAMILY SSF51735 1 141 8.37E-16 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS14230 6fbf71773d6b7617e4a199be2a29aae5 341 Gene3D G3DSA:3.40.50.720 1 179 4.9E-38 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS14230 6fbf71773d6b7617e4a199be2a29aae5 341 Gene3D G3DSA:1.10.1040.10 180 312 2.1E-29 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAK77_RS14230 6fbf71773d6b7617e4a199be2a29aae5 341 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 2 313 1.6E-66 T 06-07-2017 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0015940|GO:0016491|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 CAK77_RS14230 6fbf71773d6b7617e4a199be2a29aae5 341 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 173 311 1.8E-24 T 06-07-2017 IPR013752 Ketopantoate reductase, C-terminal domain GO:0016491|GO:0050661|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 CAK77_RS14230 6fbf71773d6b7617e4a199be2a29aae5 341 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 153 9.3E-34 T 06-07-2017 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 CAK77_RS11690 fb77d781bfe3bd0fbe072edb637748ca 615 Pfam PF13531 Bacterial extracellular solute-binding protein 106 389 9.5E-18 T 06-07-2017 CAK77_RS11690 fb77d781bfe3bd0fbe072edb637748ca 615 Gene3D G3DSA:3.40.50.410 495 603 8.6E-4 T 06-07-2017 IPR002035 von Willebrand factor, type A CAK77_RS11690 fb77d781bfe3bd0fbe072edb637748ca 615 SUPERFAMILY SSF53300 458 598 5.93E-7 T 06-07-2017 IPR002035 von Willebrand factor, type A CAK77_RS16180 8cd06e268f982c878ae8ac331195ef7f 198 Hamap MF_00276 Potassium-transporting ATPase KdpC subunit [kdpC]. 9 193 27.222 T 06-07-2017 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 CAK77_RS16180 8cd06e268f982c878ae8ac331195ef7f 198 PIRSF PIRSF001296 9 195 1.8E-49 T 06-07-2017 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 CAK77_RS16180 8cd06e268f982c878ae8ac331195ef7f 198 Pfam PF02669 K+-transporting ATPase, c chain 14 190 1.2E-52 T 06-07-2017 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 CAK77_RS07035 e18533527f98b03a760c6f1ac9230354 203 SUPERFAMILY SSF46689 9 88 1.7E-19 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS07035 e18533527f98b03a760c6f1ac9230354 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 4.1E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS07035 e18533527f98b03a760c6f1ac9230354 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 4.1E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS07035 e18533527f98b03a760c6f1ac9230354 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 60 9.9E-17 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS07035 e18533527f98b03a760c6f1ac9230354 203 Gene3D G3DSA:1.10.357.10 14 191 1.4E-25 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS12570 a96deae11d3b6dee399e09be62391361 308 Pfam PF00296 Luciferase-like monooxygenase 25 121 1.8E-10 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS12570 a96deae11d3b6dee399e09be62391361 308 Gene3D G3DSA:3.20.20.30 171 298 3.1E-7 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS12570 a96deae11d3b6dee399e09be62391361 308 SUPERFAMILY SSF51679 24 265 4.71E-24 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS12570 a96deae11d3b6dee399e09be62391361 308 Gene3D G3DSA:3.20.20.30 25 121 6.6E-11 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS12570 a96deae11d3b6dee399e09be62391361 308 TIGRFAM TIGR03620 F420_MSMEG_4141: probable F420-dependent oxidoreductase, MSMEG_4141 family 8 263 5.0E-81 T 06-07-2017 IPR019922 Luciferase-like, F420-dependent oxidoreductase, MSMEG4141, predicted CAK77_RS23085 068317f9ae520b033a4acbfc2a2883f9 364 Gene3D G3DSA:3.30.230.10 4 192 3.4E-60 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CAK77_RS23085 068317f9ae520b033a4acbfc2a2883f9 364 Gene3D G3DSA:3.30.70.890 193 361 4.3E-52 T 06-07-2017 IPR013750 GHMP kinase, C-terminal domain CAK77_RS23085 068317f9ae520b033a4acbfc2a2883f9 364 SUPERFAMILY SSF55060 189 362 6.3E-43 T 06-07-2017 IPR013750 GHMP kinase, C-terminal domain CAK77_RS23085 068317f9ae520b033a4acbfc2a2883f9 364 ProSitePatterns PS00106 Galactokinase signature. 9 20 - T 06-07-2017 IPR019741 Galactokinase, conserved site KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CAK77_RS23085 068317f9ae520b033a4acbfc2a2883f9 364 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 102 113 - T 06-07-2017 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 CAK77_RS23085 068317f9ae520b033a4acbfc2a2883f9 364 Pfam PF00288 GHMP kinases N terminal domain 95 161 3.8E-13 T 06-07-2017 IPR006204 GHMP kinase N-terminal domain GO:0005524 CAK77_RS23085 068317f9ae520b033a4acbfc2a2883f9 364 PRINTS PR00473 Galactokinase signature 245 259 1.4E-23 T 06-07-2017 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CAK77_RS23085 068317f9ae520b033a4acbfc2a2883f9 364 PRINTS PR00473 Galactokinase signature 73 84 1.4E-23 T 06-07-2017 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CAK77_RS23085 068317f9ae520b033a4acbfc2a2883f9 364 PRINTS PR00473 Galactokinase signature 93 111 1.4E-23 T 06-07-2017 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CAK77_RS23085 068317f9ae520b033a4acbfc2a2883f9 364 PRINTS PR00473 Galactokinase signature 9 27 1.4E-23 T 06-07-2017 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CAK77_RS23085 068317f9ae520b033a4acbfc2a2883f9 364 PRINTS PR00959 Mevalonate kinase family signature 100 122 3.7E-39 T 06-07-2017 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CAK77_RS23085 068317f9ae520b033a4acbfc2a2883f9 364 PRINTS PR00959 Mevalonate kinase family signature 143 162 3.7E-39 T 06-07-2017 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CAK77_RS23085 068317f9ae520b033a4acbfc2a2883f9 364 PRINTS PR00959 Mevalonate kinase family signature 7 31 3.7E-39 T 06-07-2017 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CAK77_RS23085 068317f9ae520b033a4acbfc2a2883f9 364 PRINTS PR00959 Mevalonate kinase family signature 309 326 3.7E-39 T 06-07-2017 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CAK77_RS23085 068317f9ae520b033a4acbfc2a2883f9 364 SUPERFAMILY SSF54211 3 183 2.13E-49 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAK77_RS23085 068317f9ae520b033a4acbfc2a2883f9 364 TIGRFAM TIGR00131 gal_kin: galactokinase 5 362 1.3E-80 T 06-07-2017 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CAK77_RS23085 068317f9ae520b033a4acbfc2a2883f9 364 PIRSF PIRSF000530 2 364 1.1E-106 T 06-07-2017 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CAK77_RS23085 068317f9ae520b033a4acbfc2a2883f9 364 Pfam PF10509 Galactokinase galactose-binding signature 4 34 1.1E-14 T 06-07-2017 IPR019539 Galactokinase galactose-binding domain KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CAK77_RS23085 068317f9ae520b033a4acbfc2a2883f9 364 Pfam PF08544 GHMP kinases C terminal 268 341 5.8E-12 T 06-07-2017 IPR013750 GHMP kinase, C-terminal domain CAK77_RS04785 e9f568faaf208056f4dc52d0ae3c7d5b 144 PIRSF PIRSF009151 7 139 1.5E-62 T 06-07-2017 IPR008497 Protein of unknown function DUF779 CAK77_RS04785 e9f568faaf208056f4dc52d0ae3c7d5b 144 Pfam PF05610 Protein of unknown function (DUF779) 30 124 9.7E-50 T 06-07-2017 IPR008497 Protein of unknown function DUF779 CAK77_RS10405 90c2fba418ffda11122b830f4abda1f4 792 SUPERFAMILY SSF53706 549 665 3.7E-80 T 06-07-2017 CAK77_RS10405 90c2fba418ffda11122b830f4abda1f4 792 SUPERFAMILY SSF53706 226 513 3.7E-80 T 06-07-2017 CAK77_RS10405 90c2fba418ffda11122b830f4abda1f4 792 Gene3D G3DSA:2.40.40.20 672 771 2.9E-5 T 06-07-2017 CAK77_RS10405 90c2fba418ffda11122b830f4abda1f4 792 Pfam PF00384 Molybdopterin oxidoreductase 496 624 9.8E-6 T 06-07-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS10405 90c2fba418ffda11122b830f4abda1f4 792 Pfam PF00384 Molybdopterin oxidoreductase 284 440 1.8E-15 T 06-07-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS10405 90c2fba418ffda11122b830f4abda1f4 792 Gene3D G3DSA:3.40.228.10 367 449 5.4E-6 T 06-07-2017 CAK77_RS10405 90c2fba418ffda11122b830f4abda1f4 792 TIGRFAM TIGR01973 NuoG: NADH dehydrogenase (quinone), G subunit 13 639 6.1E-167 T 06-07-2017 IPR010228 NADH:ubiquinone oxidoreductase, subunit G GO:0016651|GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS10405 90c2fba418ffda11122b830f4abda1f4 792 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 40 57 - T 06-07-2017 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS10405 90c2fba418ffda11122b830f4abda1f4 792 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 96 133 1.2E-15 T 06-07-2017 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS10405 90c2fba418ffda11122b830f4abda1f4 792 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 10 84 3.5E-18 T 06-07-2017 CAK77_RS10405 90c2fba418ffda11122b830f4abda1f4 792 SUPERFAMILY SSF54862 87 223 8.37E-29 T 06-07-2017 CAK77_RS10405 90c2fba418ffda11122b830f4abda1f4 792 ProSitePatterns PS00643 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. 157 167 - T 06-07-2017 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS10405 90c2fba418ffda11122b830f4abda1f4 792 Gene3D G3DSA:3.10.20.30 10 67 2.2E-6 T 06-07-2017 IPR012675 Beta-grasp domain CAK77_RS10405 90c2fba418ffda11122b830f4abda1f4 792 SMART SM00926 227 281 4.5E-6 T 06-07-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS10405 90c2fba418ffda11122b830f4abda1f4 792 SUPERFAMILY SSF50692 686 770 1.47E-6 T 06-07-2017 IPR009010 Aspartate decarboxylase-like domain CAK77_RS10405 90c2fba418ffda11122b830f4abda1f4 792 SMART SM00929 94 134 2.4E-18 T 06-07-2017 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS10405 90c2fba418ffda11122b830f4abda1f4 792 SUPERFAMILY SSF54292 11 83 3.42E-18 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK77_RS10405 90c2fba418ffda11122b830f4abda1f4 792 Gene3D G3DSA:3.40.50.740 533 663 3.5E-38 T 06-07-2017 CAK77_RS10405 90c2fba418ffda11122b830f4abda1f4 792 Gene3D G3DSA:3.40.50.740 462 499 3.5E-38 T 06-07-2017 CAK77_RS10405 90c2fba418ffda11122b830f4abda1f4 792 Gene3D G3DSA:3.40.50.740 284 352 3.5E-38 T 06-07-2017 CAK77_RS10405 90c2fba418ffda11122b830f4abda1f4 792 ProSitePatterns PS00642 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. 109 121 - T 06-07-2017 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS10405 90c2fba418ffda11122b830f4abda1f4 792 Gene3D G3DSA:2.20.25.90 230 279 2.5E-10 T 06-07-2017 CAK77_RS18335 3b60d2a559c8cc5d947d88c88fc43f3c 429 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 140 151 5.6E-9 T 06-07-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CAK77_RS18335 3b60d2a559c8cc5d947d88c88fc43f3c 429 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 214 227 5.6E-9 T 06-07-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CAK77_RS18335 3b60d2a559c8cc5d947d88c88fc43f3c 429 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 188 205 5.6E-9 T 06-07-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CAK77_RS18335 3b60d2a559c8cc5d947d88c88fc43f3c 429 SUPERFAMILY SSF56601 112 358 7.27E-55 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK77_RS18335 3b60d2a559c8cc5d947d88c88fc43f3c 429 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 109 335 9.6E-38 T 06-07-2017 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 CAK77_RS18335 3b60d2a559c8cc5d947d88c88fc43f3c 429 Gene3D G3DSA:3.40.710.10 109 358 1.6E-70 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK77_RS00530 ec73a3021d18cd82e3b67c4f6234420c 405 Gene3D G3DSA:2.40.110.10 121 213 1.4E-27 T 06-07-2017 CAK77_RS00530 ec73a3021d18cd82e3b67c4f6234420c 405 SUPERFAMILY SSF56645 16 218 3.01E-28 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK77_RS00530 ec73a3021d18cd82e3b67c4f6234420c 405 Gene3D G3DSA:1.20.140.10 214 401 6.7E-57 T 06-07-2017 CAK77_RS00530 ec73a3021d18cd82e3b67c4f6234420c 405 PIRSF PIRSF016578 5 404 1.6E-136 T 06-07-2017 CAK77_RS00530 ec73a3021d18cd82e3b67c4f6234420c 405 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 249 380 7.5E-41 T 06-07-2017 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain CAK77_RS00530 ec73a3021d18cd82e3b67c4f6234420c 405 Gene3D G3DSA:1.10.540.10 14 118 4.7E-35 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS00530 ec73a3021d18cd82e3b67c4f6234420c 405 SUPERFAMILY SSF47203 239 376 6.11E-17 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS19385 e665afa310bd960499d90f3f3a32409d 209 Gene3D G3DSA:1.10.357.10 30 207 3.8E-25 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS19385 e665afa310bd960499d90f3f3a32409d 209 Pfam PF00440 Bacterial regulatory proteins, tetR family 33 78 9.7E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS19385 e665afa310bd960499d90f3f3a32409d 209 SUPERFAMILY SSF48498 96 207 1.37E-6 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS19385 e665afa310bd960499d90f3f3a32409d 209 SUPERFAMILY SSF46689 28 88 4.99E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS19385 e665afa310bd960499d90f3f3a32409d 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 46 2.9E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS19385 e665afa310bd960499d90f3f3a32409d 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 54 77 2.9E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS13795 507839d804725950a0b83a8e1ec81dcd 415 Gene3D G3DSA:3.40.50.1950 3 175 3.1E-56 T 06-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CAK77_RS13795 507839d804725950a0b83a8e1ec81dcd 415 Pfam PF02441 Flavoprotein 3 128 4.6E-25 T 06-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CAK77_RS13795 507839d804725950a0b83a8e1ec81dcd 415 Gene3D G3DSA:3.40.50.10300 181 413 1.7E-73 T 06-07-2017 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CAK77_RS13795 507839d804725950a0b83a8e1ec81dcd 415 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 3 410 1.5E-109 T 06-07-2017 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5 CAK77_RS13795 507839d804725950a0b83a8e1ec81dcd 415 SUPERFAMILY SSF102645 177 414 2.75E-61 T 06-07-2017 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CAK77_RS13795 507839d804725950a0b83a8e1ec81dcd 415 SUPERFAMILY SSF52507 3 169 1.96E-53 T 06-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CAK77_RS13795 507839d804725950a0b83a8e1ec81dcd 415 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 184 381 1.6E-64 T 06-07-2017 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CAK77_RS10130 6ff13e0f743c313a676659c260055151 146 SUPERFAMILY SSF53098 2 130 3.79E-18 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAK77_RS10130 6ff13e0f743c313a676659c260055151 146 Pfam PF00665 Integrase core domain 1 83 1.7E-9 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 CAK77_RS10130 6ff13e0f743c313a676659c260055151 146 Gene3D G3DSA:3.30.420.10 1 125 2.6E-16 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAK77_RS19140 c2a1002430f84704fe723467df904a77 101 TIGRFAM TIGR03967 mycofact_MftB: putative mycofactocin binding protein MftB 16 94 7.7E-31 T 06-07-2017 IPR023850 Putative mycofactocin binding protein MftB CAK77_RS15075 f887bb905c7535d7c333b4c8ed16c18d 323 SUPERFAMILY SSF88659 220 319 2.18E-26 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS15075 f887bb905c7535d7c333b4c8ed16c18d 323 SUPERFAMILY SSF88946 25 160 1.11E-50 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS15075 f887bb905c7535d7c333b4c8ed16c18d 323 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 86 311 7.0E-38 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS15075 f887bb905c7535d7c333b4c8ed16c18d 323 Gene3D G3DSA:1.10.601.10 11 159 9.0E-63 T 06-07-2017 CAK77_RS15075 f887bb905c7535d7c333b4c8ed16c18d 323 Gene3D G3DSA:1.10.10.10 163 214 6.6E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS15075 f887bb905c7535d7c333b4c8ed16c18d 323 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 114 127 - T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS15075 f887bb905c7535d7c333b4c8ed16c18d 323 PRINTS PR00046 Major sigma-70 factor signature 138 146 4.9E-28 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS15075 f887bb905c7535d7c333b4c8ed16c18d 323 PRINTS PR00046 Major sigma-70 factor signature 298 309 4.9E-28 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS15075 f887bb905c7535d7c333b4c8ed16c18d 323 PRINTS PR00046 Major sigma-70 factor signature 262 274 4.9E-28 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS15075 f887bb905c7535d7c333b4c8ed16c18d 323 PRINTS PR00046 Major sigma-70 factor signature 283 298 4.9E-28 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS15075 f887bb905c7535d7c333b4c8ed16c18d 323 PRINTS PR00046 Major sigma-70 factor signature 114 127 4.9E-28 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS15075 f887bb905c7535d7c333b4c8ed16c18d 323 Pfam PF04545 Sigma-70, region 4 258 311 5.3E-19 T 06-07-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS15075 f887bb905c7535d7c333b4c8ed16c18d 323 Pfam PF04539 Sigma-70 region 3 169 245 8.5E-26 T 06-07-2017 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS15075 f887bb905c7535d7c333b4c8ed16c18d 323 Gene3D G3DSA:1.10.10.10 254 322 9.9E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS15075 f887bb905c7535d7c333b4c8ed16c18d 323 Pfam PF00140 Sigma-70 factor, region 1.2 25 58 2.6E-14 T 06-07-2017 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS15075 f887bb905c7535d7c333b4c8ed16c18d 323 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 283 309 - T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS15075 f887bb905c7535d7c333b4c8ed16c18d 323 Pfam PF04542 Sigma-70 region 2 90 159 1.3E-21 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS15075 f887bb905c7535d7c333b4c8ed16c18d 323 SUPERFAMILY SSF88659 163 236 4.05E-19 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS01110 515a700e3ba4d72041d6b37125d346b6 1085 Pfam PF04602 Mycobacterial cell wall arabinan synthesis protein 31 681 3.1E-283 T 06-07-2017 IPR007680 Arabinofuranosyltransferase, N-terminal GO:0052636|GO:0071766 CAK77_RS01110 515a700e3ba4d72041d6b37125d346b6 1085 Pfam PF14896 EmbC C-terminal domain 717 1082 3.9E-145 T 06-07-2017 IPR032731 Arabinosyltransferase, C-terminal CAK77_RS01110 515a700e3ba4d72041d6b37125d346b6 1085 Gene3D G3DSA:2.60.120.610 52 233 9.6E-64 T 06-07-2017 IPR027451 Arabinofuranosyltransferase, domain 1 CAK77_RS13445 145218b5203464c4cb495ea5fbd21c5e 114 Pfam PF01883 Domain of unknown function DUF59 12 81 5.2E-18 T 06-07-2017 IPR002744 Domain of unknown function DUF59 CAK77_RS13445 145218b5203464c4cb495ea5fbd21c5e 114 SUPERFAMILY SSF117916 12 108 4.9E-25 T 06-07-2017 CAK77_RS14720 290646a8dbc63e4f0ce2283d1262bc8f 679 PRINTS PR01217 Proline rich extensin signature 453 469 1.0E-8 T 06-07-2017 CAK77_RS14720 290646a8dbc63e4f0ce2283d1262bc8f 679 PRINTS PR01217 Proline rich extensin signature 532 549 1.0E-8 T 06-07-2017 CAK77_RS14720 290646a8dbc63e4f0ce2283d1262bc8f 679 PRINTS PR01217 Proline rich extensin signature 475 487 1.0E-8 T 06-07-2017 CAK77_RS14720 290646a8dbc63e4f0ce2283d1262bc8f 679 PRINTS PR01217 Proline rich extensin signature 552 577 1.0E-8 T 06-07-2017 CAK77_RS14720 290646a8dbc63e4f0ce2283d1262bc8f 679 PRINTS PR01217 Proline rich extensin signature 514 530 1.0E-8 T 06-07-2017 CAK77_RS14720 290646a8dbc63e4f0ce2283d1262bc8f 679 PRINTS PR01217 Proline rich extensin signature 490 511 1.0E-8 T 06-07-2017 CAK77_RS12200 ed855bd2e6c68ffeb451d098565b865d 71 SMART SM00704 20 64 1.3E-4 T 06-07-2017 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 CAK77_RS12200 ed855bd2e6c68ffeb451d098565b865d 71 Pfam PF09360 Iron-binding zinc finger CDGSH type 15 59 8.4E-13 T 06-07-2017 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 CAK77_RS01855 6187865218e7e7c0b411ca2f51599aaa 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 143 151 1.6E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS01855 6187865218e7e7c0b411ca2f51599aaa 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 1.6E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS01855 6187865218e7e7c0b411ca2f51599aaa 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 163 182 1.6E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS01855 6187865218e7e7c0b411ca2f51599aaa 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 254 1.5E-44 T 06-07-2017 CAK77_RS01855 6187865218e7e7c0b411ca2f51599aaa 259 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 150 178 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK77_RS01855 6187865218e7e7c0b411ca2f51599aaa 259 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 194 0.0035 T 06-07-2017 CAK77_RS01855 6187865218e7e7c0b411ca2f51599aaa 259 SUPERFAMILY SSF51735 8 255 9.53E-58 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS01855 6187865218e7e7c0b411ca2f51599aaa 259 Gene3D G3DSA:3.40.50.720 2 255 4.4E-66 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS01855 6187865218e7e7c0b411ca2f51599aaa 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 3.1E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS01855 6187865218e7e7c0b411ca2f51599aaa 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 220 240 3.1E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS01855 6187865218e7e7c0b411ca2f51599aaa 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 182 3.1E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS01855 6187865218e7e7c0b411ca2f51599aaa 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 184 201 3.1E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS01855 6187865218e7e7c0b411ca2f51599aaa 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 3.1E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS01855 6187865218e7e7c0b411ca2f51599aaa 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 137 153 3.1E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS09275 baf9fd240d9609340a598f455cf987ba 479 SUPERFAMILY SSF55154 4 194 1.46E-44 T 06-07-2017 IPR033469 CYTH-like domain Reactome: R-HSA-196819 CAK77_RS09275 baf9fd240d9609340a598f455cf987ba 479 SMART SM01118 5 194 3.9E-22 T 06-07-2017 IPR023577 CYTH domain Reactome: R-HSA-196819 CAK77_RS09275 baf9fd240d9609340a598f455cf987ba 479 SMART SM00880 208 462 2.1E-56 T 06-07-2017 IPR007899 CHAD domain CAK77_RS09275 baf9fd240d9609340a598f455cf987ba 479 Pfam PF01928 CYTH domain 7 167 1.6E-14 T 06-07-2017 IPR023577 CYTH domain Reactome: R-HSA-196819 CAK77_RS09275 baf9fd240d9609340a598f455cf987ba 479 Gene3D G3DSA:2.40.320.10 4 197 7.8E-58 T 06-07-2017 IPR023577 CYTH domain Reactome: R-HSA-196819 CAK77_RS09275 baf9fd240d9609340a598f455cf987ba 479 Pfam PF05235 CHAD domain 209 429 1.4E-44 T 06-07-2017 IPR007899 CHAD domain CAK77_RS06070 803f864e2f2ecfb752ea81010459792e 260 Pfam PF01255 Putative undecaprenyl diphosphate synthase 37 259 4.0E-70 T 06-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CAK77_RS06070 803f864e2f2ecfb752ea81010459792e 260 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 205 222 - T 06-07-2017 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 CAK77_RS06070 803f864e2f2ecfb752ea81010459792e 260 Gene3D G3DSA:3.40.1180.10 15 259 5.6E-85 T 06-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CAK77_RS06070 803f864e2f2ecfb752ea81010459792e 260 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 29 260 34.599 T 06-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CAK77_RS06070 803f864e2f2ecfb752ea81010459792e 260 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 30 259 1.4E-61 T 06-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CAK77_RS06070 803f864e2f2ecfb752ea81010459792e 260 SUPERFAMILY SSF64005 29 254 1.31E-70 T 06-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CAK77_RS23745 d0d206123133a1f066347ebc56bf5207 231 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 4 29 3.2E-4 T 06-07-2017 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal CAK77_RS23745 d0d206123133a1f066347ebc56bf5207 231 ProSitePatterns PS00725 Germin family signature. 110 123 - T 06-07-2017 IPR019780 Germin, manganese binding site GO:0030145 CAK77_RS23745 d0d206123133a1f066347ebc56bf5207 231 Gene3D G3DSA:2.60.120.10 53 225 1.4E-39 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK77_RS23745 d0d206123133a1f066347ebc56bf5207 231 Pfam PF00190 Cupin 79 210 1.9E-20 T 06-07-2017 IPR006045 Cupin 1 GO:0045735 CAK77_RS23745 d0d206123133a1f066347ebc56bf5207 231 SMART SM00835 68 214 6.0E-24 T 06-07-2017 IPR006045 Cupin 1 GO:0045735 CAK77_RS23745 d0d206123133a1f066347ebc56bf5207 231 SUPERFAMILY SSF51182 77 229 1.48E-31 T 06-07-2017 IPR011051 RmlC-like cupin domain CAK77_RS04780 3399eff793d5341b25c49cb492a9802e 506 SUPERFAMILY SSF53720 15 500 3.27E-165 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAK77_RS04780 3399eff793d5341b25c49cb492a9802e 506 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 262 269 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CAK77_RS04780 3399eff793d5341b25c49cb492a9802e 506 Gene3D G3DSA:3.40.309.10 271 469 3.4E-62 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAK77_RS04780 3399eff793d5341b25c49cb492a9802e 506 Gene3D G3DSA:3.40.605.10 19 270 1.2E-95 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAK77_RS04780 3399eff793d5341b25c49cb492a9802e 506 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 295 306 - T 06-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CAK77_RS04780 3399eff793d5341b25c49cb492a9802e 506 Pfam PF00171 Aldehyde dehydrogenase family 28 494 9.0E-165 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAK77_RS00540 b06f99ea2272f01d447fbb8899bc2e8d 283 SUPERFAMILY SSF55781 82 241 2.62E-37 T 06-07-2017 IPR029016 GAF domain-like CAK77_RS00540 b06f99ea2272f01d447fbb8899bc2e8d 283 Gene3D G3DSA:1.10.10.10 10 76 8.1E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS00540 b06f99ea2272f01d447fbb8899bc2e8d 283 SUPERFAMILY SSF46785 14 81 1.64E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS00540 b06f99ea2272f01d447fbb8899bc2e8d 283 SMART SM00346 11 98 9.5E-18 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAK77_RS00540 b06f99ea2272f01d447fbb8899bc2e8d 283 Gene3D G3DSA:3.30.450.40 77 245 1.7E-42 T 06-07-2017 IPR029016 GAF domain-like CAK77_RS00540 b06f99ea2272f01d447fbb8899bc2e8d 283 Pfam PF01614 Bacterial transcriptional regulator 128 241 2.0E-24 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAK77_RS00540 b06f99ea2272f01d447fbb8899bc2e8d 283 Pfam PF09339 IclR helix-turn-helix domain 14 63 2.8E-14 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAK77_RS11700 988a7f6017f564ae82f3c71fc34d224f 351 Pfam PF01595 Domain of unknown function DUF21 9 203 1.5E-40 T 06-07-2017 IPR002550 Domain of unknown function DUF21 CAK77_RS11700 988a7f6017f564ae82f3c71fc34d224f 351 SUPERFAMILY SSF54631 208 349 3.16E-17 T 06-07-2017 CAK77_RS11700 988a7f6017f564ae82f3c71fc34d224f 351 Pfam PF00571 CBS domain 292 339 7.3E-4 T 06-07-2017 IPR000644 CBS domain CAK77_RS11700 988a7f6017f564ae82f3c71fc34d224f 351 Gene3D G3DSA:3.10.580.10 241 340 3.3E-10 T 06-07-2017 CAK77_RS12595 a778cec38630af5986e4e5af265e48c5 431 Pfam PF06508 Queuosine biosynthesis protein QueC 274 358 4.6E-5 T 06-07-2017 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 CAK77_RS12595 a778cec38630af5986e4e5af265e48c5 431 SUPERFAMILY SSF52402 284 370 1.5E-6 T 06-07-2017 CAK77_RS12595 a778cec38630af5986e4e5af265e48c5 431 Gene3D G3DSA:3.40.50.620 139 370 1.5E-11 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS16325 07e2e4b7161d08e044ba2a02f339736c 551 SUPERFAMILY SSF101473 6 201 3.01E-34 T 06-07-2017 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CAK77_RS16325 07e2e4b7161d08e044ba2a02f339736c 551 TIGRFAM TIGR03599 YloV: DAK2 domain fusion protein YloV 12 551 6.9E-151 T 06-07-2017 IPR019986 DAK2 domain-containing protein YloV CAK77_RS16325 07e2e4b7161d08e044ba2a02f339736c 551 SMART SM01121 245 551 3.7E-72 T 06-07-2017 IPR033470 Uncharacterised protein, DhaK domain CAK77_RS16325 07e2e4b7161d08e044ba2a02f339736c 551 SMART SM01120 36 200 1.3E-47 T 06-07-2017 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CAK77_RS16325 07e2e4b7161d08e044ba2a02f339736c 551 Pfam PF13684 Dihydroxyacetone kinase family 247 551 1.0E-70 T 06-07-2017 IPR033470 Uncharacterised protein, DhaK domain CAK77_RS16325 07e2e4b7161d08e044ba2a02f339736c 551 Pfam PF02734 DAK2 domain 36 199 3.1E-34 T 06-07-2017 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CAK77_RS04805 d70359609a4912a4a0cd99dfeac0d7fd 401 Pfam PF11799 impB/mucB/samB family C-terminal domain 237 342 2.9E-15 T 06-07-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CAK77_RS04805 d70359609a4912a4a0cd99dfeac0d7fd 401 Gene3D G3DSA:3.30.1490.100 241 348 1.3E-18 T 06-07-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CAK77_RS04805 d70359609a4912a4a0cd99dfeac0d7fd 401 Pfam PF00817 impB/mucB/samB family 11 151 5.0E-45 T 06-07-2017 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CAK77_RS04805 d70359609a4912a4a0cd99dfeac0d7fd 401 Hamap MF_01113 DNA polymerase IV [dinB]. 4 351 33.176 T 06-07-2017 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 CAK77_RS04805 d70359609a4912a4a0cd99dfeac0d7fd 401 Pfam PF11798 IMS family HHH motif 167 195 1.2E-7 T 06-07-2017 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 CAK77_RS04805 d70359609a4912a4a0cd99dfeac0d7fd 401 SUPERFAMILY SSF100879 237 340 1.57E-18 T 06-07-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CAK77_RS04805 d70359609a4912a4a0cd99dfeac0d7fd 401 Gene3D G3DSA:3.30.70.270 64 162 3.6E-28 T 06-07-2017 CAK77_RS04805 d70359609a4912a4a0cd99dfeac0d7fd 401 Gene3D G3DSA:1.10.150.20 164 233 2.5E-21 T 06-07-2017 CAK77_RS04805 d70359609a4912a4a0cd99dfeac0d7fd 401 SUPERFAMILY SSF56672 6 233 2.58E-76 T 06-07-2017 CAK77_RS17595 0b977a8ef79e6fd14bde567b85381944 310 SUPERFAMILY SSF55811 111 277 1.35E-40 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAK77_RS17595 0b977a8ef79e6fd14bde567b85381944 310 Pfam PF09296 NADH pyrophosphatase-like rudimentary NUDIX domain 64 123 4.1E-5 T 06-07-2017 IPR015375 NADH pyrophosphatase-like, N-terminal GO:0016787 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381 CAK77_RS17595 0b977a8ef79e6fd14bde567b85381944 310 Pfam PF00293 NUDIX domain 161 271 4.1E-17 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 CAK77_RS17595 0b977a8ef79e6fd14bde567b85381944 310 Gene3D G3DSA:3.90.79.10 121 277 1.0E-40 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAK77_RS17595 0b977a8ef79e6fd14bde567b85381944 310 Pfam PF09297 NADH pyrophosphatase zinc ribbon domain 126 156 3.1E-6 T 06-07-2017 IPR015376 Zinc ribbon, NADH pyrophosphatase GO:0016787|GO:0046872 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381 CAK77_RS17595 0b977a8ef79e6fd14bde567b85381944 310 ProSitePatterns PS00893 Nudix box signature. 192 213 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CAK77_RS17765 e0aff59458e66bb0e8a4aef2046c8b32 431 Gene3D G3DSA:3.65.10.10 25 237 5.3E-52 T 06-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 CAK77_RS17765 e0aff59458e66bb0e8a4aef2046c8b32 431 PIRSF PIRSF000505 5 430 1.8E-107 T 06-07-2017 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CAK77_RS17765 e0aff59458e66bb0e8a4aef2046c8b32 431 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 18 425 9.3E-99 T 06-07-2017 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CAK77_RS17765 e0aff59458e66bb0e8a4aef2046c8b32 431 ProSitePatterns PS00885 EPSP synthase signature 2. 339 357 - T 06-07-2017 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CAK77_RS17765 e0aff59458e66bb0e8a4aef2046c8b32 431 ProSitePatterns PS00104 EPSP synthase signature 1. 91 105 - T 06-07-2017 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CAK77_RS17765 e0aff59458e66bb0e8a4aef2046c8b32 431 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 14 417 2.6E-101 T 06-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 CAK77_RS17765 e0aff59458e66bb0e8a4aef2046c8b32 431 SUPERFAMILY SSF55205 14 422 3.11E-87 T 06-07-2017 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 CAK77_RS17765 e0aff59458e66bb0e8a4aef2046c8b32 431 Gene3D G3DSA:3.65.10.10 238 423 2.0E-45 T 06-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 CAK77_RS17765 e0aff59458e66bb0e8a4aef2046c8b32 431 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 13 426 27.391 T 06-07-2017 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CAK77_RS09200 bd2e118bcd0cb456a6f60f47c2adcfbf 216 Pfam PF13419 Haloacid dehalogenase-like hydrolase 3 180 8.0E-30 T 06-07-2017 IPR023214 HAD-like domain CAK77_RS09200 bd2e118bcd0cb456a6f60f47c2adcfbf 216 SUPERFAMILY SSF56784 2 200 5.42E-47 T 06-07-2017 IPR023214 HAD-like domain CAK77_RS09200 bd2e118bcd0cb456a6f60f47c2adcfbf 216 Gene3D G3DSA:1.10.150.240 14 69 3.7E-19 T 06-07-2017 IPR023198 Phosphoglycolate phosphatase, domain 2 CAK77_RS09200 bd2e118bcd0cb456a6f60f47c2adcfbf 216 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 84 174 5.2E-7 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAK77_RS09200 bd2e118bcd0cb456a6f60f47c2adcfbf 216 Gene3D G3DSA:3.40.50.1000 70 201 2.0E-37 T 06-07-2017 IPR023214 HAD-like domain CAK77_RS05205 05c661b8f00b551d6f19a095279cb7a0 756 TIGRFAM TIGR02778 ligD_pol: DNA ligase D, polymerase domain 1 249 3.6E-85 T 06-07-2017 IPR014145 DNA ligase D, polymerase domain CAK77_RS05205 05c661b8f00b551d6f19a095279cb7a0 756 Gene3D G3DSA:3.30.470.30 479 585 7.2E-28 T 06-07-2017 CAK77_RS05205 05c661b8f00b551d6f19a095279cb7a0 756 TIGRFAM TIGR02777 LigD_PE_dom: DNA ligase D, 3'-phosphoesterase domain 285 443 1.2E-59 T 06-07-2017 IPR014144 DNA ligase D, 3'-phosphoesterase domain CAK77_RS05205 05c661b8f00b551d6f19a095279cb7a0 756 Pfam PF04679 ATP dependent DNA ligase C terminal region 652 746 1.9E-20 T 06-07-2017 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 CAK77_RS05205 05c661b8f00b551d6f19a095279cb7a0 756 TIGRFAM TIGR02779 NHEJ_ligase_lig: DNA ligase D, ligase domain 456 752 4.9E-88 T 06-07-2017 IPR014146 DNA ligase D, ligase domain CAK77_RS05205 05c661b8f00b551d6f19a095279cb7a0 756 SUPERFAMILY SSF56091 442 633 1.19E-39 T 06-07-2017 CAK77_RS05205 05c661b8f00b551d6f19a095279cb7a0 756 Gene3D G3DSA:3.30.1490.70 590 633 3.6E-18 T 06-07-2017 CAK77_RS05205 05c661b8f00b551d6f19a095279cb7a0 756 Gene3D G3DSA:3.30.1490.70 450 478 3.6E-18 T 06-07-2017 CAK77_RS05205 05c661b8f00b551d6f19a095279cb7a0 756 Pfam PF01068 ATP dependent DNA ligase domain 467 632 8.7E-26 T 06-07-2017 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 CAK77_RS05205 05c661b8f00b551d6f19a095279cb7a0 756 SUPERFAMILY SSF50249 635 751 5.31E-24 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS05205 05c661b8f00b551d6f19a095279cb7a0 756 Gene3D G3DSA:2.40.50.140 635 752 6.0E-41 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS05205 05c661b8f00b551d6f19a095279cb7a0 756 Pfam PF13298 DNA polymerase Ligase (LigD) 317 428 1.1E-37 T 06-07-2017 IPR014144 DNA ligase D, 3'-phosphoesterase domain CAK77_RS00480 1d812ddf3428215318661ee39b97e09c 381 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 338 357 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CAK77_RS00480 1d812ddf3428215318661ee39b97e09c 381 SUPERFAMILY SSF47203 229 379 4.03E-45 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS00480 1d812ddf3428215318661ee39b97e09c 381 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 120 1.5E-32 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS00480 1d812ddf3428215318661ee39b97e09c 381 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 126 138 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CAK77_RS00480 1d812ddf3428215318661ee39b97e09c 381 Gene3D G3DSA:2.40.110.10 124 221 1.1E-41 T 06-07-2017 CAK77_RS00480 1d812ddf3428215318661ee39b97e09c 381 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 231 379 4.4E-40 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS00480 1d812ddf3428215318661ee39b97e09c 381 SUPERFAMILY SSF56645 4 244 2.62E-83 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK77_RS00480 1d812ddf3428215318661ee39b97e09c 381 Gene3D G3DSA:1.10.540.10 5 122 3.6E-36 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS00480 1d812ddf3428215318661ee39b97e09c 381 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 124 219 7.6E-28 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAK77_RS00480 1d812ddf3428215318661ee39b97e09c 381 Gene3D G3DSA:1.20.140.10 222 379 1.2E-53 T 06-07-2017 CAK77_RS22765 bc5865b4dda15848df7e2dcd4be91597 228 Gene3D G3DSA:1.10.10.60 15 65 3.0E-20 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS22765 bc5865b4dda15848df7e2dcd4be91597 228 Gene3D G3DSA:1.10.357.10 66 206 7.5E-26 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS22765 bc5865b4dda15848df7e2dcd4be91597 228 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 67 7.4E-15 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS22765 bc5865b4dda15848df7e2dcd4be91597 228 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 68 5.4E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS22765 bc5865b4dda15848df7e2dcd4be91597 228 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 24 37 5.4E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS22765 bc5865b4dda15848df7e2dcd4be91597 228 SUPERFAMILY SSF48498 89 208 2.23E-21 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS22765 bc5865b4dda15848df7e2dcd4be91597 228 SUPERFAMILY SSF46689 15 83 4.77E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS11360 08c47c8b7b207bbcca25348f75fc8bb8 351 Gene3D G3DSA:3.30.930.10 22 347 4.1E-117 T 06-07-2017 CAK77_RS11360 08c47c8b7b207bbcca25348f75fc8bb8 351 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 33 100 8.6E-18 T 06-07-2017 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 CAK77_RS11360 08c47c8b7b207bbcca25348f75fc8bb8 351 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 53 343 2.5E-85 T 06-07-2017 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 CAK77_RS11360 08c47c8b7b207bbcca25348f75fc8bb8 351 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 21 347 43.744 T 06-07-2017 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 CAK77_RS11360 08c47c8b7b207bbcca25348f75fc8bb8 351 Pfam PF01409 tRNA synthetases class II core domain (F) 105 344 5.1E-97 T 06-07-2017 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 CAK77_RS11360 08c47c8b7b207bbcca25348f75fc8bb8 351 SUPERFAMILY SSF46589 27 111 2.09E-16 T 06-07-2017 IPR010978 tRNA-binding arm GO:0000166 CAK77_RS11360 08c47c8b7b207bbcca25348f75fc8bb8 351 SUPERFAMILY SSF55681 105 343 5.6E-73 T 06-07-2017 CAK77_RS00970 d29d5ea4d0e60ab82eef7c29458b43d2 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 1.1E-18 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK77_RS00970 d29d5ea4d0e60ab82eef7c29458b43d2 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.3E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK77_RS00970 d29d5ea4d0e60ab82eef7c29458b43d2 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.3E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK77_RS00970 d29d5ea4d0e60ab82eef7c29458b43d2 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.3E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK77_RS00970 d29d5ea4d0e60ab82eef7c29458b43d2 296 Gene3D G3DSA:1.10.10.10 1 80 6.1E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS00970 d29d5ea4d0e60ab82eef7c29458b43d2 296 Gene3D G3DSA:3.40.190.10 85 192 3.7E-21 T 06-07-2017 CAK77_RS00970 d29d5ea4d0e60ab82eef7c29458b43d2 296 SUPERFAMILY SSF46785 1 110 2.21E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS00970 d29d5ea4d0e60ab82eef7c29458b43d2 296 Pfam PF03466 LysR substrate binding domain 86 284 2.6E-38 T 06-07-2017 IPR005119 LysR, substrate-binding CAK77_RS00970 d29d5ea4d0e60ab82eef7c29458b43d2 296 Gene3D G3DSA:3.40.190.10 193 254 8.2E-12 T 06-07-2017 CAK77_RS00970 d29d5ea4d0e60ab82eef7c29458b43d2 296 SUPERFAMILY SSF53850 87 285 7.47E-33 T 06-07-2017 CAK77_RS05995 fa443fcbf78844406a413a1572c338a7 358 SUPERFAMILY SSF53474 85 342 3.68E-43 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS05995 fa443fcbf78844406a413a1572c338a7 358 Pfam PF07859 alpha/beta hydrolase fold 120 320 2.2E-40 T 06-07-2017 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CAK77_RS05995 fa443fcbf78844406a413a1572c338a7 358 Gene3D G3DSA:3.40.50.1820 100 342 1.6E-49 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS09775 a5d044002334ba964a1c759dd052a610 235 Gene3D G3DSA:3.60.140.10 4 234 1.1E-85 T 06-07-2017 IPR003730 Multi-copper polyphenol oxidoreductase, laccase CAK77_RS09775 a5d044002334ba964a1c759dd052a610 235 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 15 234 2.2E-60 T 06-07-2017 IPR003730 Multi-copper polyphenol oxidoreductase, laccase CAK77_RS09775 a5d044002334ba964a1c759dd052a610 235 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 10 233 7.1E-73 T 06-07-2017 IPR003730 Multi-copper polyphenol oxidoreductase, laccase CAK77_RS09775 a5d044002334ba964a1c759dd052a610 235 SUPERFAMILY SSF64438 4 234 1.39E-77 T 06-07-2017 IPR011324 Cytotoxic necrotizing factor-like, catalytic CAK77_RS11030 7b25533c347e78c5b7966ddb365282fb 207 Pfam PF13411 MerR HTH family regulatory protein 12 56 1.8E-9 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAK77_RS11030 7b25533c347e78c5b7966ddb365282fb 207 SMART SM00422 11 80 0.0041 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAK77_RS11030 7b25533c347e78c5b7966ddb365282fb 207 SUPERFAMILY SSF46955 12 129 7.33E-18 T 06-07-2017 IPR009061 Putative DNA-binding domain CAK77_RS11030 7b25533c347e78c5b7966ddb365282fb 207 Gene3D G3DSA:1.10.1660.10 12 129 1.0E-18 T 06-07-2017 CAK77_RS13895 f79966bcfd4faf2ed1b5daa080e394ab 372 SUPERFAMILY SSF56796 9 358 2.49E-99 T 06-07-2017 CAK77_RS13895 f79966bcfd4faf2ed1b5daa080e394ab 372 Gene3D G3DSA:3.40.50.1970 14 175 4.5E-53 T 06-07-2017 CAK77_RS13895 f79966bcfd4faf2ed1b5daa080e394ab 372 PIRSF PIRSF001455 10 353 5.2E-97 T 06-07-2017 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CAK77_RS13895 f79966bcfd4faf2ed1b5daa080e394ab 372 Pfam PF01761 3-dehydroquinate synthase 71 327 1.3E-92 T 06-07-2017 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CAK77_RS13895 f79966bcfd4faf2ed1b5daa080e394ab 372 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 7 360 37.215 T 06-07-2017 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CAK77_RS13895 f79966bcfd4faf2ed1b5daa080e394ab 372 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 17 343 2.8E-103 T 06-07-2017 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CAK77_RS13895 f79966bcfd4faf2ed1b5daa080e394ab 372 Gene3D G3DSA:1.20.1090.10 177 358 1.3E-58 T 06-07-2017 CAK77_RS20115 3971c3775c221821a35cd24c4dc70407 287 SUPERFAMILY SSF102588 1 286 6.93E-55 T 06-07-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CAK77_RS20115 3971c3775c221821a35cd24c4dc70407 287 TIGRFAM TIGR03446 mycothiol_Mca: mycothiol conjugate amidase Mca 1 287 4.7E-97 T 06-07-2017 IPR017811 Mycothiol S-conjugate amidase Mca GO:0010126 KEGG: 00311+3.5.1.11 CAK77_RS20115 3971c3775c221821a35cd24c4dc70407 287 Pfam PF02585 GlcNAc-PI de-N-acetylase 1 144 5.5E-25 T 06-07-2017 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 CAK77_RS20115 3971c3775c221821a35cd24c4dc70407 287 Gene3D G3DSA:3.40.50.10320 1 287 2.4E-73 T 06-07-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CAK77_RS09830 3130c3952827894c7c79417c61be289a 187 Gene3D G3DSA:1.20.1290.10 32 166 1.7E-24 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAK77_RS09830 3130c3952827894c7c79417c61be289a 187 SUPERFAMILY SSF69118 6 165 1.75E-26 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAK77_RS09830 3130c3952827894c7c79417c61be289a 187 Pfam PF02627 Carboxymuconolactone decarboxylase family 45 102 2.5E-10 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CAK77_RS22420 aebc0a8506ee2e9e9dd26d97fa694cdb 1002 SUPERFAMILY SSF82866 499 717 7.46E-30 T 06-07-2017 CAK77_RS22420 aebc0a8506ee2e9e9dd26d97fa694cdb 1002 Gene3D G3DSA:1.20.1640.10 167 354 6.6E-31 T 06-07-2017 CAK77_RS22420 aebc0a8506ee2e9e9dd26d97fa694cdb 1002 Gene3D G3DSA:1.20.1640.10 508 723 1.4E-30 T 06-07-2017 CAK77_RS22420 aebc0a8506ee2e9e9dd26d97fa694cdb 1002 Pfam PF03176 MMPL family 423 719 1.2E-27 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 CAK77_RS22420 aebc0a8506ee2e9e9dd26d97fa694cdb 1002 Pfam PF03176 MMPL family 47 388 8.9E-45 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 CAK77_RS22420 aebc0a8506ee2e9e9dd26d97fa694cdb 1002 SUPERFAMILY SSF82866 164 353 1.1E-29 T 06-07-2017 CAK77_RS18600 2f9ae8c45719bc33c9c4a506e937777b 396 SUPERFAMILY SSF140453 12 86 6.41E-5 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like CAK77_RS21660 566ee5e57c74f22b64318c6860b8ea84 267 Gene3D G3DSA:3.90.260.10 156 213 2.1E-5 T 06-07-2017 IPR002931 Transglutaminase-like CAK77_RS21660 566ee5e57c74f22b64318c6860b8ea84 267 Pfam PF01841 Transglutaminase-like superfamily 115 209 2.3E-19 T 06-07-2017 IPR002931 Transglutaminase-like CAK77_RS21660 566ee5e57c74f22b64318c6860b8ea84 267 SUPERFAMILY SSF54001 97 237 5.33E-26 T 06-07-2017 CAK77_RS21660 566ee5e57c74f22b64318c6860b8ea84 267 SMART SM00460 151 211 1.1E-11 T 06-07-2017 IPR002931 Transglutaminase-like CAK77_RS18115 a072a81035f50e28d442ed195db96017 329 Gene3D G3DSA:3.20.20.30 4 324 4.8E-79 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS18115 a072a81035f50e28d442ed195db96017 329 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 5 324 2.8E-117 T 06-07-2017 IPR019949 Luciferase family oxidoreductase, group 1 CAK77_RS18115 a072a81035f50e28d442ed195db96017 329 Pfam PF00296 Luciferase-like monooxygenase 12 297 2.4E-35 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS18115 a072a81035f50e28d442ed195db96017 329 SUPERFAMILY SSF51679 5 324 6.28E-73 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS13460 14ec9898c39c7a62a5fca805822f8f43 254 Gene3D G3DSA:3.40.50.300 3 239 1.6E-45 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS13460 14ec9898c39c7a62a5fca805822f8f43 254 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 4 247 2.4E-104 T 06-07-2017 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524|GO:0006810 CAK77_RS13460 14ec9898c39c7a62a5fca805822f8f43 254 SMART SM00382 33 234 2.2E-4 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS13460 14ec9898c39c7a62a5fca805822f8f43 254 SUPERFAMILY SSF52540 3 235 8.68E-41 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS13460 14ec9898c39c7a62a5fca805822f8f43 254 Pfam PF00005 ABC transporter 24 175 4.6E-22 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK77_RS23240 4a2569ee1c82d86f65b5bcb20c7a6eb6 557 Gene3D G3DSA:3.30.300.30 441 545 1.6E-13 T 06-07-2017 CAK77_RS23240 4a2569ee1c82d86f65b5bcb20c7a6eb6 557 SUPERFAMILY SSF56801 50 550 1.83E-88 T 06-07-2017 CAK77_RS23240 4a2569ee1c82d86f65b5bcb20c7a6eb6 557 Gene3D G3DSA:3.40.50.980 179 341 4.7E-30 T 06-07-2017 CAK77_RS23240 4a2569ee1c82d86f65b5bcb20c7a6eb6 557 ProSitePatterns PS00455 Putative AMP-binding domain signature. 173 184 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK77_RS23240 4a2569ee1c82d86f65b5bcb20c7a6eb6 557 Gene3D G3DSA:2.30.38.10 370 440 1.7E-15 T 06-07-2017 CAK77_RS23240 4a2569ee1c82d86f65b5bcb20c7a6eb6 557 Pfam PF00501 AMP-binding enzyme 60 449 5.2E-63 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK77_RS23240 4a2569ee1c82d86f65b5bcb20c7a6eb6 557 Gene3D G3DSA:3.40.50.980 52 178 1.2E-15 T 06-07-2017 CAK77_RS14915 f21b38a2c1ab1c15746c35cc33071839 123 Gene3D G3DSA:2.40.50.140 37 122 8.5E-11 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS14915 f21b38a2c1ab1c15746c35cc33071839 123 Pfam PF17191 RecG wedge domain 38 120 4.5E-5 T 06-07-2017 IPR033454 RecG, wedge domain CAK77_RS14915 f21b38a2c1ab1c15746c35cc33071839 123 PIRSF PIRSF006910 1 123 1.6E-59 T 06-07-2017 IPR016499 Nucleic acid binding protein, Rv2694c, predicted CAK77_RS03215 df1a775d01ae171f1491d169bf2637b3 285 Pfam PF13452 N-terminal half of MaoC dehydratase 9 133 2.9E-18 T 06-07-2017 CAK77_RS03215 df1a775d01ae171f1491d169bf2637b3 285 SUPERFAMILY SSF54637 162 276 4.65E-26 T 06-07-2017 IPR029069 HotDog domain CAK77_RS03215 df1a775d01ae171f1491d169bf2637b3 285 SUPERFAMILY SSF54637 9 158 6.5E-41 T 06-07-2017 IPR029069 HotDog domain CAK77_RS03215 df1a775d01ae171f1491d169bf2637b3 285 Gene3D G3DSA:3.10.129.10 146 277 2.7E-36 T 06-07-2017 IPR029069 HotDog domain CAK77_RS03215 df1a775d01ae171f1491d169bf2637b3 285 Gene3D G3DSA:3.10.129.10 1 145 2.4E-49 T 06-07-2017 IPR029069 HotDog domain CAK77_RS03215 df1a775d01ae171f1491d169bf2637b3 285 Pfam PF01575 MaoC like domain 163 261 2.1E-28 T 06-07-2017 IPR002539 MaoC-like domain CAK77_RS02265 962c54713103d01146743da12f00855a 811 Gene3D G3DSA:1.10.3810.10 75 258 4.5E-62 T 06-07-2017 CAK77_RS02265 962c54713103d01146743da12f00855a 811 SUPERFAMILY SSF53955 63 288 2.42E-61 T 06-07-2017 IPR023346 Lysozyme-like domain CAK77_RS02265 962c54713103d01146743da12f00855a 811 Gene3D G3DSA:3.40.710.10 259 726 1.2E-72 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK77_RS02265 962c54713103d01146743da12f00855a 811 SMART SM00740 702 767 2.6E-8 T 06-07-2017 IPR005543 PASTA domain CAK77_RS02265 962c54713103d01146743da12f00855a 811 Pfam PF00912 Transglycosylase 76 260 6.3E-55 T 06-07-2017 IPR001264 Glycosyl transferase, family 51 CAK77_RS02265 962c54713103d01146743da12f00855a 811 Pfam PF00905 Penicillin binding protein transpeptidase domain 369 626 1.8E-20 T 06-07-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CAK77_RS02265 962c54713103d01146743da12f00855a 811 SUPERFAMILY SSF56601 299 696 7.73E-72 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK77_RS02265 962c54713103d01146743da12f00855a 811 SUPERFAMILY SSF56601 242 264 7.73E-72 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK77_RS02265 962c54713103d01146743da12f00855a 811 Pfam PF03793 PASTA domain 707 766 3.2E-7 T 06-07-2017 IPR005543 PASTA domain CAK77_RS07240 ec12b8715914455954d0c201ff62a8bf 280 Gene3D G3DSA:3.40.50.150 86 275 5.2E-52 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS07240 ec12b8715914455954d0c201ff62a8bf 280 SUPERFAMILY SSF53335 15 263 2.2E-43 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS07240 ec12b8715914455954d0c201ff62a8bf 280 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 180 186 - T 06-07-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CAK77_RS07240 ec12b8715914455954d0c201ff62a8bf 280 Pfam PF05175 Methyltransferase small domain 109 189 1.5E-11 T 06-07-2017 IPR007848 Methyltransferase small domain GO:0008168 CAK77_RS07240 ec12b8715914455954d0c201ff62a8bf 280 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 4 275 38.374 T 06-07-2017 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 CAK77_RS07240 ec12b8715914455954d0c201ff62a8bf 280 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 5 276 2.9E-43 T 06-07-2017 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 CAK77_RS07240 ec12b8715914455954d0c201ff62a8bf 280 Gene3D G3DSA:1.10.8.10 4 81 3.3E-16 T 06-07-2017 CAK77_RS07240 ec12b8715914455954d0c201ff62a8bf 280 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 26 271 5.4E-62 T 06-07-2017 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 CAK77_RS05960 38b425647fbd0ea48f6ed0df51ad4027 343 Pfam PF16113 Enoyl-CoA hydratase/isomerase 13 333 2.3E-119 T 06-07-2017 IPR032259 Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type GO:0003860 Reactome: R-HSA-70895 CAK77_RS05960 38b425647fbd0ea48f6ed0df51ad4027 343 Gene3D G3DSA:3.90.226.10 3 197 1.4E-56 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS05960 38b425647fbd0ea48f6ed0df51ad4027 343 SUPERFAMILY SSF52096 4 194 3.56E-66 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS05960 38b425647fbd0ea48f6ed0df51ad4027 343 SUPERFAMILY SSF52096 246 315 3.56E-66 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS05960 38b425647fbd0ea48f6ed0df51ad4027 343 Gene3D G3DSA:1.10.12.10 259 316 3.3E-6 T 06-07-2017 IPR014748 Crontonase, C-terminal CAK77_RS14765 3776dceec24b7b59e564386a5587afa5 456 Gene3D G3DSA:3.90.1200.10 284 324 2.0E-4 T 06-07-2017 CAK77_RS14765 3776dceec24b7b59e564386a5587afa5 456 SUPERFAMILY SSF56112 103 161 4.54E-19 T 06-07-2017 IPR011009 Protein kinase-like domain CAK77_RS14765 3776dceec24b7b59e564386a5587afa5 456 SUPERFAMILY SSF56112 199 312 4.54E-19 T 06-07-2017 IPR011009 Protein kinase-like domain CAK77_RS14765 3776dceec24b7b59e564386a5587afa5 456 Pfam PF03109 ABC1 family 120 229 3.4E-30 T 06-07-2017 IPR004147 UbiB domain CAK77_RS11670 93e2f57dc5bfa02cb5b364d20298cad4 247 Pfam PF00376 MerR family regulatory protein 24 54 3.8E-11 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAK77_RS11670 93e2f57dc5bfa02cb5b364d20298cad4 247 SUPERFAMILY SSF46955 27 91 7.78E-13 T 06-07-2017 IPR009061 Putative DNA-binding domain CAK77_RS11670 93e2f57dc5bfa02cb5b364d20298cad4 247 SMART SM00422 12 86 1.3E-21 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAK77_RS11670 93e2f57dc5bfa02cb5b364d20298cad4 247 Gene3D G3DSA:1.10.1660.10 12 90 1.0E-17 T 06-07-2017 CAK77_RS12910 634f9310677b63f3234c3c6dd2f350c5 356 Pfam PF02653 Branched-chain amino acid transport system / permease component 32 339 6.6E-44 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK77_RS14345 cd5845e22d0ea9bfd0d3eab88ff07f82 124 SUPERFAMILY SSF50129 11 64 9.92E-10 T 06-07-2017 IPR011032 GroES-like CAK77_RS14345 cd5845e22d0ea9bfd0d3eab88ff07f82 124 SUPERFAMILY SSF51735 52 120 1.65E-14 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS14345 cd5845e22d0ea9bfd0d3eab88ff07f82 124 Gene3D G3DSA:3.90.180.10 12 119 2.1E-29 T 06-07-2017 IPR011032 GroES-like CAK77_RS03435 fb58717c23b6e4d957b4c3b646a24611 1386 SUPERFAMILY SSF52777 14 162 5.34E-7 T 06-07-2017 CAK77_RS03435 fb58717c23b6e4d957b4c3b646a24611 1386 Gene3D G3DSA:3.30.300.30 841 949 1.3E-9 T 06-07-2017 CAK77_RS03435 fb58717c23b6e4d957b4c3b646a24611 1386 Gene3D G3DSA:3.40.50.980 606 760 5.7E-30 T 06-07-2017 CAK77_RS03435 fb58717c23b6e4d957b4c3b646a24611 1386 ProSitePatterns PS00455 Putative AMP-binding domain signature. 596 607 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK77_RS03435 fb58717c23b6e4d957b4c3b646a24611 1386 Pfam PF00550 Phosphopantetheine attachment site 951 1009 2.9E-4 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS03435 fb58717c23b6e4d957b4c3b646a24611 1386 Pfam PF00501 AMP-binding enzyme 494 844 1.5E-36 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK77_RS03435 fb58717c23b6e4d957b4c3b646a24611 1386 Gene3D G3DSA:2.30.38.10 781 837 4.8E-4 T 06-07-2017 CAK77_RS03435 fb58717c23b6e4d957b4c3b646a24611 1386 SUPERFAMILY SSF56801 485 959 4.06E-64 T 06-07-2017 CAK77_RS03435 fb58717c23b6e4d957b4c3b646a24611 1386 Gene3D G3DSA:3.40.50.980 494 605 1.1E-9 T 06-07-2017 CAK77_RS03435 fb58717c23b6e4d957b4c3b646a24611 1386 Pfam PF01370 NAD dependent epimerase/dehydratase family 1055 1231 4.5E-7 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 CAK77_RS03435 fb58717c23b6e4d957b4c3b646a24611 1386 Gene3D G3DSA:3.40.50.720 1054 1300 4.9E-17 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS03435 fb58717c23b6e4d957b4c3b646a24611 1386 SUPERFAMILY SSF47336 945 1010 9.07E-6 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS03435 fb58717c23b6e4d957b4c3b646a24611 1386 SUPERFAMILY SSF51735 1055 1302 3.85E-22 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS03435 fb58717c23b6e4d957b4c3b646a24611 1386 Gene3D G3DSA:1.10.1200.10 950 1011 9.9E-9 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS03435 fb58717c23b6e4d957b4c3b646a24611 1386 SUPERFAMILY SSF52777 228 432 3.11E-7 T 06-07-2017 CAK77_RS19270 e1aa0708b2ef1a4ef396b35ce15b5f24 233 SUPERFAMILY SSF54909 119 170 2.44E-7 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAK77_RS19270 e1aa0708b2ef1a4ef396b35ce15b5f24 233 Gene3D G3DSA:3.30.70.900 119 169 5.8E-4 T 06-07-2017 CAK77_RS10285 1d01f7702113a885e52941473f7abcab 412 Gene3D G3DSA:3.40.50.620 35 329 1.5E-73 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS10285 1d01f7702113a885e52941473f7abcab 412 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 37 336 5.0E-83 T 06-07-2017 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 CAK77_RS10285 1d01f7702113a885e52941473f7abcab 412 Hamap MF_01697 L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase [mshC]. 9 412 52.406 T 06-07-2017 IPR017812 Mycothiol ligase MshC GO:0010125|GO:0035446 CAK77_RS10285 1d01f7702113a885e52941473f7abcab 412 TIGRFAM TIGR03447 mycothiol_MshC: cysteine--1-D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase 2 412 1.9E-213 T 06-07-2017 IPR017812 Mycothiol ligase MshC GO:0010125|GO:0035446 CAK77_RS10285 1d01f7702113a885e52941473f7abcab 412 Gene3D G3DSA:1.20.120.640 333 410 1.2E-5 T 06-07-2017 CAK77_RS10285 1d01f7702113a885e52941473f7abcab 412 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 40 51 2.4E-24 T 06-07-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CAK77_RS10285 1d01f7702113a885e52941473f7abcab 412 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 213 231 2.4E-24 T 06-07-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CAK77_RS10285 1d01f7702113a885e52941473f7abcab 412 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 244 265 2.4E-24 T 06-07-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CAK77_RS10285 1d01f7702113a885e52941473f7abcab 412 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 76 85 2.4E-24 T 06-07-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CAK77_RS10285 1d01f7702113a885e52941473f7abcab 412 SUPERFAMILY SSF52374 28 336 4.83E-70 T 06-07-2017 CAK77_RS05530 2df03a6c94a22a3de98e9384a7ad82c3 297 PIRSF PIRSF007580 2 291 2.3E-62 T 06-07-2017 IPR016516 Uncharacterised conserved protein UCP07580 CAK77_RS05530 2df03a6c94a22a3de98e9384a7ad82c3 297 SUPERFAMILY SSF47240 59 199 5.77E-6 T 06-07-2017 IPR009078 Ferritin-like superfamily CAK77_RS05530 2df03a6c94a22a3de98e9384a7ad82c3 297 Pfam PF10118 Predicted metal-dependent hydrolase 11 273 8.0E-71 T 06-07-2017 IPR016516 Uncharacterised conserved protein UCP07580 CAK77_RS04850 7e2901f89f7fdc9e8ea2610554c3c191 262 Gene3D G3DSA:1.10.10.10 11 110 2.0E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS04850 7e2901f89f7fdc9e8ea2610554c3c191 262 SMART SM00418 12 94 3.4E-14 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK77_RS04850 7e2901f89f7fdc9e8ea2610554c3c191 262 SUPERFAMILY SSF46785 13 108 1.53E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS04850 7e2901f89f7fdc9e8ea2610554c3c191 262 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 14 29 1.4E-5 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK77_RS04850 7e2901f89f7fdc9e8ea2610554c3c191 262 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 62 77 1.4E-5 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK77_RS04850 7e2901f89f7fdc9e8ea2610554c3c191 262 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 47 62 1.4E-5 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK77_RS04850 7e2901f89f7fdc9e8ea2610554c3c191 262 Gene3D G3DSA:3.30.530.20 111 260 2.7E-36 T 06-07-2017 IPR023393 START-like domain CAK77_RS04850 7e2901f89f7fdc9e8ea2610554c3c191 262 SUPERFAMILY SSF55961 110 255 1.81E-38 T 06-07-2017 CAK77_RS04850 7e2901f89f7fdc9e8ea2610554c3c191 262 Pfam PF12840 Helix-turn-helix domain 13 71 1.1E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS04850 7e2901f89f7fdc9e8ea2610554c3c191 262 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 127 248 5.2E-20 T 06-07-2017 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CAK77_RS18410 9dd21f14495d3e84f5a4c551f806d327 136 Pfam PF01638 HxlR-like helix-turn-helix 29 115 5.9E-27 T 06-07-2017 IPR002577 Helix-turn-helix, HxlR type CAK77_RS18410 9dd21f14495d3e84f5a4c551f806d327 136 SUPERFAMILY SSF46785 14 123 4.18E-33 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS18410 9dd21f14495d3e84f5a4c551f806d327 136 Gene3D G3DSA:1.10.10.10 13 126 8.9E-45 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS16510 6f59a7eff24a0c626d8ce12136b714cd 337 Hamap MF_00435 Ketol-acid reductoisomerase [ilvC]. 3 330 45.192 T 06-07-2017 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CAK77_RS16510 6f59a7eff24a0c626d8ce12136b714cd 337 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 16 179 1.4E-72 T 06-07-2017 IPR013116 Acetohydroxy acid isomeroreductase, NADPH-binding domain KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CAK77_RS16510 6f59a7eff24a0c626d8ce12136b714cd 337 SUPERFAMILY SSF48179 185 330 5.95E-66 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAK77_RS16510 6f59a7eff24a0c626d8ce12136b714cd 337 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 185 328 4.3E-61 T 06-07-2017 IPR000506 Acetohydroxy acid isomeroreductase C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CAK77_RS16510 6f59a7eff24a0c626d8ce12136b714cd 337 Gene3D G3DSA:1.10.1040.10 31 327 9.0E-107 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAK77_RS16510 6f59a7eff24a0c626d8ce12136b714cd 337 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 16 328 1.5E-123 T 06-07-2017 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CAK77_RS16510 6f59a7eff24a0c626d8ce12136b714cd 337 SUPERFAMILY SSF51735 4 183 4.39E-71 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS00430 bf3f1ed04b07bddf68ab370e3e09028c 166 Gene3D G3DSA:3.40.140.10 3 144 1.1E-34 T 06-07-2017 CAK77_RS00430 bf3f1ed04b07bddf68ab370e3e09028c 166 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 49 86 - T 06-07-2017 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 CAK77_RS00430 bf3f1ed04b07bddf68ab370e3e09028c 166 Pfam PF14437 MafB19-like deaminase 5 90 1.9E-18 T 06-07-2017 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 CAK77_RS00430 bf3f1ed04b07bddf68ab370e3e09028c 166 SUPERFAMILY SSF53927 4 120 7.44E-34 T 06-07-2017 IPR016193 Cytidine deaminase-like GO:0003824 CAK77_RS21170 60dfaa63440cf1425a814f155e6400f0 753 SUPERFAMILY SSF56112 136 413 4.18E-44 T 06-07-2017 IPR011009 Protein kinase-like domain CAK77_RS21170 60dfaa63440cf1425a814f155e6400f0 753 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 275 287 - T 06-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CAK77_RS21170 60dfaa63440cf1425a814f155e6400f0 753 Gene3D G3DSA:3.30.200.20 144 234 9.0E-13 T 06-07-2017 CAK77_RS21170 60dfaa63440cf1425a814f155e6400f0 753 SMART SM00220 154 396 4.1E-26 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CAK77_RS21170 60dfaa63440cf1425a814f155e6400f0 753 SUPERFAMILY SSF48452 507 637 5.6E-8 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK77_RS21170 60dfaa63440cf1425a814f155e6400f0 753 Pfam PF00069 Protein kinase domain 157 347 6.6E-31 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CAK77_RS21170 60dfaa63440cf1425a814f155e6400f0 753 Gene3D G3DSA:1.10.510.10 235 345 1.2E-23 T 06-07-2017 CAK77_RS21170 60dfaa63440cf1425a814f155e6400f0 753 Pfam PF16918 Protein kinase G tetratricopeptide repeat 412 751 1.8E-150 T 06-07-2017 IPR031636 Protein kinase G, tetratricopeptide repeat containing domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 CAK77_RS21170 60dfaa63440cf1425a814f155e6400f0 753 Pfam PF16919 Protein kinase G rubredoxin domain 17 153 5.0E-55 T 06-07-2017 IPR031634 Protein kinase G, rubredoxin domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 CAK77_RS21170 60dfaa63440cf1425a814f155e6400f0 753 Gene3D G3DSA:1.25.40.10 512 631 5.2E-7 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK77_RS14640 325b030333c25ea12e92457bcb492f1c 325 SUPERFAMILY SSF88713 14 313 4.45E-84 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CAK77_RS14640 325b030333c25ea12e92457bcb492f1c 325 TIGRFAM TIGR03212 uraD_N-term-dom: putative urate catabolism protein 15 313 1.3E-152 T 06-07-2017 IPR017625 Putative urate catabolism protein CAK77_RS14640 325b030333c25ea12e92457bcb492f1c 325 Gene3D G3DSA:3.20.20.370 14 314 6.9E-100 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAK77_RS14640 325b030333c25ea12e92457bcb492f1c 325 Pfam PF01522 Polysaccharide deacetylase 84 172 2.0E-11 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAK77_RS07635 0313c650fa3ab4e96a545e5c8cc4e55e 78 Pfam PF12277 Protein of unknown function (DUF3618) 2 47 4.2E-17 T 06-07-2017 IPR022062 Protein of unknown function DUF3618 CAK77_RS23860 096bd90f3546167a4fbfc3fc6f0b8126 281 SUPERFAMILY SSF160387 95 225 1.88E-27 T 06-07-2017 CAK77_RS23860 096bd90f3546167a4fbfc3fc6f0b8126 281 Pfam PF03243 Alkylmercury lyase 93 210 1.1E-24 T 06-07-2017 IPR004927 Alkylmercury lyase GO:0018836|GO:0046413 CAK77_RS11540 14e5169826177bf6403384665b99508c 263 Gene3D G3DSA:3.10.290.10 21 85 5.0E-22 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 CAK77_RS11540 14e5169826177bf6403384665b99508c 263 Pfam PF00849 RNA pseudouridylate synthase 85 219 2.6E-18 T 06-07-2017 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAK77_RS11540 14e5169826177bf6403384665b99508c 263 SMART SM00363 23 82 3.0E-6 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 CAK77_RS11540 14e5169826177bf6403384665b99508c 263 Pfam PF01479 S4 domain 24 65 2.3E-11 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 CAK77_RS11540 14e5169826177bf6403384665b99508c 263 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 125 139 - T 06-07-2017 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 CAK77_RS11540 14e5169826177bf6403384665b99508c 263 SUPERFAMILY SSF55174 17 75 1.2E-13 T 06-07-2017 CAK77_RS11540 14e5169826177bf6403384665b99508c 263 SUPERFAMILY SSF55120 77 261 1.92E-41 T 06-07-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAK77_RS11540 14e5169826177bf6403384665b99508c 263 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 89 249 3.9E-45 T 06-07-2017 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 CAK77_RS15745 fd3a9463c6be1d80daa0d40cc362609f 267 Gene3D G3DSA:3.90.230.10 23 266 2.0E-95 T 06-07-2017 IPR000994 Peptidase M24, structural domain CAK77_RS15745 fd3a9463c6be1d80daa0d40cc362609f 267 Hamap MF_01974 Methionine aminopeptidase [map]. 21 267 40.558 T 06-07-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 CAK77_RS15745 fd3a9463c6be1d80daa0d40cc362609f 267 SUPERFAMILY SSF55920 23 265 6.67E-87 T 06-07-2017 IPR000994 Peptidase M24, structural domain CAK77_RS15745 fd3a9463c6be1d80daa0d40cc362609f 267 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 23 265 1.2E-90 T 06-07-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 CAK77_RS15745 fd3a9463c6be1d80daa0d40cc362609f 267 Pfam PF00557 Metallopeptidase family M24 30 258 5.4E-52 T 06-07-2017 IPR000994 Peptidase M24, structural domain CAK77_RS15745 fd3a9463c6be1d80daa0d40cc362609f 267 PRINTS PR00599 Methionine aminopeptidase-1 signature 178 190 8.1E-22 T 06-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase CAK77_RS15745 fd3a9463c6be1d80daa0d40cc362609f 267 PRINTS PR00599 Methionine aminopeptidase-1 signature 209 221 8.1E-22 T 06-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase CAK77_RS15745 fd3a9463c6be1d80daa0d40cc362609f 267 PRINTS PR00599 Methionine aminopeptidase-1 signature 86 99 8.1E-22 T 06-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase CAK77_RS15745 fd3a9463c6be1d80daa0d40cc362609f 267 PRINTS PR00599 Methionine aminopeptidase-1 signature 108 124 8.1E-22 T 06-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase CAK77_RS15745 fd3a9463c6be1d80daa0d40cc362609f 267 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 184 202 - T 06-07-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 CAK77_RS08280 58eadaf2c424400d189fbdab6d0bcb9e 221 Gene3D G3DSA:3.40.50.1240 2 214 6.9E-56 T 06-07-2017 IPR029033 Histidine phosphatase superfamily CAK77_RS08280 58eadaf2c424400d189fbdab6d0bcb9e 221 SMART SM00855 4 164 2.1E-21 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 CAK77_RS08280 58eadaf2c424400d189fbdab6d0bcb9e 221 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 7 16 - T 06-07-2017 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 CAK77_RS08280 58eadaf2c424400d189fbdab6d0bcb9e 221 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 5 211 6.7E-50 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 CAK77_RS08280 58eadaf2c424400d189fbdab6d0bcb9e 221 SUPERFAMILY SSF53254 1 192 3.53E-51 T 06-07-2017 IPR029033 Histidine phosphatase superfamily CAK77_RS10185 724ca7f2a7c670cdbb94b105a5fa6793 266 Gene3D G3DSA:1.10.260.40 14 73 9.9E-6 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK77_RS10185 724ca7f2a7c670cdbb94b105a5fa6793 266 Gene3D G3DSA:3.30.870.10 136 167 2.4E-4 T 06-07-2017 CAK77_RS10185 724ca7f2a7c670cdbb94b105a5fa6793 266 SUPERFAMILY SSF47413 13 73 5.63E-5 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK77_RS08975 5001622e63cc6041b9d78346b58a40e6 457 Gene3D G3DSA:3.50.50.60 295 372 1.2E-11 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS08975 5001622e63cc6041b9d78346b58a40e6 457 Gene3D G3DSA:3.50.50.60 8 174 1.2E-11 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS08975 5001622e63cc6041b9d78346b58a40e6 457 SUPERFAMILY SSF51905 8 168 4.05E-17 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS08975 5001622e63cc6041b9d78346b58a40e6 457 SUPERFAMILY SSF51905 304 377 4.05E-17 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS17870 961d3366f6b555125f3b2105dfdb2a24 259 Gene3D G3DSA:1.10.10.10 3 76 4.6E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS17870 961d3366f6b555125f3b2105dfdb2a24 259 Pfam PF09339 IclR helix-turn-helix domain 6 54 2.3E-10 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAK77_RS17870 961d3366f6b555125f3b2105dfdb2a24 259 SUPERFAMILY SSF55781 61 248 6.54E-36 T 06-07-2017 IPR029016 GAF domain-like CAK77_RS17870 961d3366f6b555125f3b2105dfdb2a24 259 SMART SM00346 4 94 3.7E-4 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAK77_RS17870 961d3366f6b555125f3b2105dfdb2a24 259 SUPERFAMILY SSF46785 5 76 8.65E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS17870 961d3366f6b555125f3b2105dfdb2a24 259 Pfam PF01614 Bacterial transcriptional regulator 122 246 9.5E-26 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAK77_RS17870 961d3366f6b555125f3b2105dfdb2a24 259 Gene3D G3DSA:3.30.450.40 79 248 6.2E-40 T 06-07-2017 IPR029016 GAF domain-like CAK77_RS17535 312bfb7ba55d62bfa5c460f5a687b09f 340 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 236 304 2.2E-8 T 06-07-2017 IPR008269 Peptidase S16, Lon C-terminal GO:0004176|GO:0004252|GO:0006508 CAK77_RS17535 312bfb7ba55d62bfa5c460f5a687b09f 340 SUPERFAMILY SSF54211 232 328 4.17E-19 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAK77_RS17535 312bfb7ba55d62bfa5c460f5a687b09f 340 Pfam PF13180 PDZ domain 135 193 1.1E-10 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAK77_RS17535 312bfb7ba55d62bfa5c460f5a687b09f 340 Gene3D G3DSA:3.30.230.10 233 326 1.0E-20 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CAK77_RS17535 312bfb7ba55d62bfa5c460f5a687b09f 340 Gene3D G3DSA:2.30.42.10 136 207 1.0E-12 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAK77_RS17535 312bfb7ba55d62bfa5c460f5a687b09f 340 SUPERFAMILY SSF50156 133 237 2.0E-16 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAK77_RS19260 a554374b0dd44a5a9c620a666e6e15d0 302 Pfam PF00378 Enoyl-CoA hydratase/isomerase 14 93 2.9E-10 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAK77_RS19260 a554374b0dd44a5a9c620a666e6e15d0 302 Pfam PF00378 Enoyl-CoA hydratase/isomerase 113 254 3.7E-18 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAK77_RS19260 a554374b0dd44a5a9c620a666e6e15d0 302 Gene3D G3DSA:3.90.226.10 5 244 3.3E-54 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS19260 a554374b0dd44a5a9c620a666e6e15d0 302 SUPERFAMILY SSF52096 4 250 7.29E-51 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS07280 83d3aaa637771f58861aa2711cca64e7 548 Gene3D G3DSA:2.40.30.20 6 96 1.9E-28 T 06-07-2017 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 CAK77_RS07280 83d3aaa637771f58861aa2711cca64e7 548 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 29 95 2.0E-15 T 06-07-2017 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CAK77_RS07280 83d3aaa637771f58861aa2711cca64e7 548 SUPERFAMILY SSF50615 15 97 1.14E-23 T 06-07-2017 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CAK77_RS07280 83d3aaa637771f58861aa2711cca64e7 548 Gene3D G3DSA:1.20.150.20 383 511 7.2E-55 T 06-07-2017 CAK77_RS07280 83d3aaa637771f58861aa2711cca64e7 548 Gene3D G3DSA:3.40.50.300 98 382 3.0E-108 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS07280 83d3aaa637771f58861aa2711cca64e7 548 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 4 512 49.723 T 06-07-2017 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 CAK77_RS07280 83d3aaa637771f58861aa2711cca64e7 548 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 152 375 2.3E-66 T 06-07-2017 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CAK77_RS07280 83d3aaa637771f58861aa2711cca64e7 548 SUPERFAMILY SSF52540 99 381 5.0E-94 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS07280 83d3aaa637771f58861aa2711cca64e7 548 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 366 375 - T 06-07-2017 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CAK77_RS07280 83d3aaa637771f58861aa2711cca64e7 548 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 382 507 1.4E-48 T 06-07-2017 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CAK77_RS07280 83d3aaa637771f58861aa2711cca64e7 548 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 6 512 5.5E-250 T 06-07-2017 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 CAK77_RS07280 83d3aaa637771f58861aa2711cca64e7 548 SUPERFAMILY SSF47917 383 511 1.81E-48 T 06-07-2017 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CAK77_RS16680 ff5c67e0614dd0b3e928fe8d27e66c0f 328 Pfam PF03405 Fatty acid desaturase 8 319 2.3E-81 T 06-07-2017 IPR005067 Fatty acid desaturase, type 2 GO:0006631|GO:0045300|GO:0055114 CAK77_RS16680 ff5c67e0614dd0b3e928fe8d27e66c0f 328 PIRSF PIRSF000346 1 327 6.8E-98 T 06-07-2017 IPR005067 Fatty acid desaturase, type 2 GO:0006631|GO:0045300|GO:0055114 CAK77_RS16680 ff5c67e0614dd0b3e928fe8d27e66c0f 328 Gene3D G3DSA:1.10.620.20 4 314 1.7E-106 T 06-07-2017 IPR012348 Ribonucleotide reductase-related GO:0016491|GO:0055114 Reactome: R-HSA-499943 CAK77_RS16680 ff5c67e0614dd0b3e928fe8d27e66c0f 328 SUPERFAMILY SSF47240 5 313 5.95E-82 T 06-07-2017 IPR009078 Ferritin-like superfamily CAK77_RS21355 8ef9bb2792c9d5ae0d7027df74b7803f 431 Gene3D G3DSA:3.40.440.10 195 265 3.4E-64 T 06-07-2017 CAK77_RS21355 8ef9bb2792c9d5ae0d7027df74b7803f 431 Gene3D G3DSA:3.40.440.10 2 94 3.4E-64 T 06-07-2017 CAK77_RS21355 8ef9bb2792c9d5ae0d7027df74b7803f 431 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 431 197.606 T 06-07-2017 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CAK77_RS21355 8ef9bb2792c9d5ae0d7027df74b7803f 431 SMART SM00788 3 423 1.0E-267 T 06-07-2017 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CAK77_RS21355 8ef9bb2792c9d5ae0d7027df74b7803f 431 Gene3D G3DSA:1.10.300.10 102 194 1.8E-34 T 06-07-2017 CAK77_RS21355 8ef9bb2792c9d5ae0d7027df74b7803f 431 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 06-07-2017 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CAK77_RS21355 8ef9bb2792c9d5ae0d7027df74b7803f 431 Gene3D G3DSA:3.90.170.10 267 424 3.0E-67 T 06-07-2017 CAK77_RS21355 8ef9bb2792c9d5ae0d7027df74b7803f 431 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 5 426 8.7E-160 T 06-07-2017 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CAK77_RS21355 8ef9bb2792c9d5ae0d7027df74b7803f 431 SUPERFAMILY SSF52540 1 428 6.59E-166 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS21355 8ef9bb2792c9d5ae0d7027df74b7803f 431 Pfam PF00709 Adenylosuccinate synthetase 4 422 2.4E-168 T 06-07-2017 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CAK77_RS21355 8ef9bb2792c9d5ae0d7027df74b7803f 431 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 132 143 - T 06-07-2017 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CAK77_RS08455 d9f4d085d2f76f045597d3f3da50ed83 430 SUPERFAMILY SSF52540 2 212 5.77E-51 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS08455 d9f4d085d2f76f045597d3f3da50ed83 430 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 58 73 - T 06-07-2017 IPR031157 Tr-type G domain, conserved site CAK77_RS08455 d9f4d085d2f76f045597d3f3da50ed83 430 SUPERFAMILY SSF50465 317 418 3.96E-24 T 06-07-2017 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal CAK77_RS08455 d9f4d085d2f76f045597d3f3da50ed83 430 Gene3D G3DSA:3.40.50.300 3 211 3.3E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS08455 d9f4d085d2f76f045597d3f3da50ed83 430 Gene3D G3DSA:2.40.30.10 226 338 2.1E-20 T 06-07-2017 CAK77_RS08455 d9f4d085d2f76f045597d3f3da50ed83 430 Pfam PF00009 Elongation factor Tu GTP binding domain 4 191 9.6E-39 T 06-07-2017 CAK77_RS08455 d9f4d085d2f76f045597d3f3da50ed83 430 PRINTS PR00315 GTP-binding elongation factor signature 65 73 2.8E-11 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAK77_RS08455 d9f4d085d2f76f045597d3f3da50ed83 430 PRINTS PR00315 GTP-binding elongation factor signature 101 112 2.8E-11 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAK77_RS08455 d9f4d085d2f76f045597d3f3da50ed83 430 PRINTS PR00315 GTP-binding elongation factor signature 6 19 2.8E-11 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAK77_RS08455 d9f4d085d2f76f045597d3f3da50ed83 430 PRINTS PR00315 GTP-binding elongation factor signature 85 95 2.8E-11 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAK77_RS08455 d9f4d085d2f76f045597d3f3da50ed83 430 PRINTS PR00315 GTP-binding elongation factor signature 138 147 2.8E-11 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAK77_RS08455 d9f4d085d2f76f045597d3f3da50ed83 430 TIGRFAM TIGR02034 CysN: sulfate adenylyltransferase, large subunit 5 418 6.4E-154 T 06-07-2017 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 CAK77_RS08455 d9f4d085d2f76f045597d3f3da50ed83 430 Gene3D G3DSA:2.40.30.10 339 418 6.7E-6 T 06-07-2017 CAK77_RS08455 d9f4d085d2f76f045597d3f3da50ed83 430 SUPERFAMILY SSF50447 226 312 8.11E-17 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain CAK77_RS24495 7933d2aa42abbb3cbb39a6056de18b2c 366 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 26 308 4.6E-42 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAK77_RS24495 7933d2aa42abbb3cbb39a6056de18b2c 366 Gene3D G3DSA:3.40.50.1100 155 322 5.3E-39 T 06-07-2017 CAK77_RS24495 7933d2aa42abbb3cbb39a6056de18b2c 366 SUPERFAMILY SSF53686 21 330 4.19E-62 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAK77_RS24495 7933d2aa42abbb3cbb39a6056de18b2c 366 Gene3D G3DSA:3.40.50.1100 58 154 1.8E-18 T 06-07-2017 CAK77_RS09065 46ce23703965347124dcbd393c2a3620 932 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 168 334 6.0E-10 T 06-07-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CAK77_RS09065 46ce23703965347124dcbd393c2a3620 932 SUPERFAMILY SSF52922 740 919 4.54E-51 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CAK77_RS09065 46ce23703965347124dcbd393c2a3620 932 PIRSF PIRSF000156 28 926 0.0 T 06-07-2017 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 CAK77_RS09065 46ce23703965347124dcbd393c2a3620 932 Gene3D G3DSA:3.40.50.920 744 922 3.9E-67 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CAK77_RS09065 46ce23703965347124dcbd393c2a3620 932 Gene3D G3DSA:3.40.50.970 88 503 5.4E-153 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK77_RS09065 46ce23703965347124dcbd393c2a3620 932 Gene3D G3DSA:3.40.50.970 508 741 9.2E-115 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK77_RS09065 46ce23703965347124dcbd393c2a3620 932 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 36 922 0.0 T 06-07-2017 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 CAK77_RS09065 46ce23703965347124dcbd393c2a3620 932 SUPERFAMILY SSF52518 88 503 1.56E-129 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK77_RS09065 46ce23703965347124dcbd393c2a3620 932 SUPERFAMILY SSF52518 508 737 5.2E-91 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK77_RS01335 59237f6af5919461ca5e8075a5005825 206 Gene3D G3DSA:1.10.357.10 3 182 1.9E-27 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS01335 59237f6af5919461ca5e8075a5005825 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 35 9.3E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS01335 59237f6af5919461ca5e8075a5005825 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 66 9.3E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS01335 59237f6af5919461ca5e8075a5005825 206 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 67 6.7E-15 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS01335 59237f6af5919461ca5e8075a5005825 206 SUPERFAMILY SSF46689 13 73 1.3E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS09025 f26396886c1734bfdf9be4657e6ac664 473 SUPERFAMILY SSF52096 184 458 5.91E-70 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS09025 f26396886c1734bfdf9be4657e6ac664 473 SUPERFAMILY SSF52096 13 209 8.96E-47 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS09025 f26396886c1734bfdf9be4657e6ac664 473 Pfam PF01039 Carboxyl transferase domain 9 459 2.5E-124 T 06-07-2017 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAK77_RS09025 f26396886c1734bfdf9be4657e6ac664 473 Gene3D G3DSA:3.90.226.10 14 209 2.0E-45 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS09025 f26396886c1734bfdf9be4657e6ac664 473 Gene3D G3DSA:3.90.226.10 225 473 1.8E-75 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS24410 9e04eecf9f878d1389e6bd37c861f006 652 SUPERFAMILY SSF56349 313 481 1.29E-7 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CAK77_RS24410 9e04eecf9f878d1389e6bd37c861f006 652 Gene3D G3DSA:1.10.443.10 312 481 7.4E-6 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAK77_RS17365 9e04eecf9f878d1389e6bd37c861f006 652 SUPERFAMILY SSF56349 313 481 1.29E-7 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CAK77_RS17365 9e04eecf9f878d1389e6bd37c861f006 652 Gene3D G3DSA:1.10.443.10 312 481 7.4E-6 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAK77_RS04125 faf818792e98575e8cd84a8b4611f8ba 158 SUPERFAMILY SSF55826 11 157 1.19E-32 T 06-07-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CAK77_RS04125 faf818792e98575e8cd84a8b4611f8ba 158 Pfam PF04073 Aminoacyl-tRNA editing domain 31 148 9.2E-26 T 06-07-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CAK77_RS04125 faf818792e98575e8cd84a8b4611f8ba 158 Gene3D G3DSA:3.90.960.10 11 157 1.9E-41 T 06-07-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CAK77_RS20005 41ca8e88baefba79ee642b44635cc8f3 84 Gene3D G3DSA:3.40.30.10 3 82 4.1E-21 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK77_RS20005 41ca8e88baefba79ee642b44635cc8f3 84 SUPERFAMILY SSF52833 2 81 2.67E-13 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK77_RS20005 41ca8e88baefba79ee642b44635cc8f3 84 Pfam PF05768 Glutaredoxin-like domain (DUF836) 4 81 1.0E-15 T 06-07-2017 IPR008554 Glutaredoxin-like CAK77_RS22665 930f11f3de5f777f2c9068656424cbea 494 Pfam PF01433 Peptidase family M1 324 370 2.8E-13 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CAK77_RS22665 930f11f3de5f777f2c9068656424cbea 494 Pfam PF01433 Peptidase family M1 54 258 6.1E-13 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CAK77_RS22665 930f11f3de5f777f2c9068656424cbea 494 Gene3D G3DSA:1.10.390.10 340 481 1.8E-15 T 06-07-2017 CAK77_RS22665 930f11f3de5f777f2c9068656424cbea 494 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 345 357 2.5E-7 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CAK77_RS22665 930f11f3de5f777f2c9068656424cbea 494 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 173 188 2.5E-7 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CAK77_RS22665 930f11f3de5f777f2c9068656424cbea 494 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 326 341 2.5E-7 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CAK77_RS22665 930f11f3de5f777f2c9068656424cbea 494 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 220 235 2.5E-7 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CAK77_RS22665 930f11f3de5f777f2c9068656424cbea 494 SUPERFAMILY SSF55486 265 481 7.62E-33 T 06-07-2017 CAK77_RS22665 930f11f3de5f777f2c9068656424cbea 494 SUPERFAMILY SSF63737 41 235 4.58E-27 T 06-07-2017 CAK77_RS16035 1d955cc8b2d20d5bcfe60565bd9bc761 414 ProSitePatterns PS00761 Signal peptidases I signature 3. 340 353 - T 06-07-2017 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 CAK77_RS16035 1d955cc8b2d20d5bcfe60565bd9bc761 414 Gene3D G3DSA:2.10.109.10 192 291 2.9E-34 T 06-07-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain CAK77_RS16035 1d955cc8b2d20d5bcfe60565bd9bc761 414 Gene3D G3DSA:2.10.109.10 335 408 2.9E-34 T 06-07-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain CAK77_RS16035 1d955cc8b2d20d5bcfe60565bd9bc761 414 Pfam PF00717 Peptidase S24-like 201 247 9.3E-8 T 06-07-2017 IPR019759 Peptidase S24/S26A/S26B CAK77_RS16035 1d955cc8b2d20d5bcfe60565bd9bc761 414 SUPERFAMILY SSF51306 276 356 7.32E-43 T 06-07-2017 IPR015927 Peptidase S24/S26A/S26B/S26C CAK77_RS16035 1d955cc8b2d20d5bcfe60565bd9bc761 414 SUPERFAMILY SSF51306 383 407 7.32E-43 T 06-07-2017 IPR015927 Peptidase S24/S26A/S26B/S26C CAK77_RS16035 1d955cc8b2d20d5bcfe60565bd9bc761 414 SUPERFAMILY SSF51306 194 245 7.32E-43 T 06-07-2017 IPR015927 Peptidase S24/S26A/S26B/S26C CAK77_RS16035 1d955cc8b2d20d5bcfe60565bd9bc761 414 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 180 355 7.1E-31 T 06-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CAK77_RS16035 1d955cc8b2d20d5bcfe60565bd9bc761 414 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 281 293 9.9E-21 T 06-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CAK77_RS16035 1d955cc8b2d20d5bcfe60565bd9bc761 414 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 335 354 9.9E-21 T 06-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CAK77_RS16035 1d955cc8b2d20d5bcfe60565bd9bc761 414 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 194 210 9.9E-21 T 06-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CAK77_RS16035 1d955cc8b2d20d5bcfe60565bd9bc761 414 ProSitePatterns PS00501 Signal peptidases I serine active site. 203 210 - T 06-07-2017 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 CAK77_RS18345 334539fc844234ca1e34fe4439593069 340 Gene3D G3DSA:1.10.240.10 218 311 5.4E-12 T 06-07-2017 CAK77_RS18345 334539fc844234ca1e34fe4439593069 340 Gene3D G3DSA:3.40.50.620 9 217 5.0E-88 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS18345 334539fc844234ca1e34fe4439593069 340 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 149 170 3.9E-27 T 06-07-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CAK77_RS18345 334539fc844234ca1e34fe4439593069 340 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 22 38 3.9E-27 T 06-07-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CAK77_RS18345 334539fc844234ca1e34fe4439593069 340 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 202 212 3.9E-27 T 06-07-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CAK77_RS18345 334539fc844234ca1e34fe4439593069 340 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 72 91 3.9E-27 T 06-07-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CAK77_RS18345 334539fc844234ca1e34fe4439593069 340 Pfam PF00579 tRNA synthetases class I (W and Y) 9 290 3.5E-82 T 06-07-2017 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK77_RS18345 334539fc844234ca1e34fe4439593069 340 SUPERFAMILY SSF52374 10 335 5.23E-96 T 06-07-2017 CAK77_RS18345 334539fc844234ca1e34fe4439593069 340 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 8 336 41.936 T 06-07-2017 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 CAK77_RS18345 334539fc844234ca1e34fe4439593069 340 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 10 335 6.5E-105 T 06-07-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CAK77_RS18345 334539fc844234ca1e34fe4439593069 340 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 17 27 - T 06-07-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK77_RS09850 30745d4dd35a09cd265711bf8ead5551 380 SUPERFAMILY SSF53901 214 378 9.69E-9 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS09850 30745d4dd35a09cd265711bf8ead5551 380 Gene3D G3DSA:3.40.47.10 20 215 2.5E-12 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS09850 30745d4dd35a09cd265711bf8ead5551 380 SUPERFAMILY SSF53901 12 231 4.85E-20 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS09850 30745d4dd35a09cd265711bf8ead5551 380 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 55 213 2.1E-8 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAK77_RS09850 30745d4dd35a09cd265711bf8ead5551 380 Gene3D G3DSA:3.40.47.10 250 378 1.0E-5 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS04670 ade1e93a929a8df4b805106cf6da6050 520 PIRSF PIRSF006060 2 519 4.3E-54 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CAK77_RS04670 ade1e93a929a8df4b805106cf6da6050 520 Pfam PF13520 Amino acid permease 27 461 1.1E-26 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CAK77_RS17220 8266516fcea190fe4bd7e08521ed0ffe 397 PIRSF PIRSF000429 1 397 3.1E-122 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 CAK77_RS17220 8266516fcea190fe4bd7e08521ed0ffe 397 SUPERFAMILY SSF53901 275 396 1.77E-40 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS17220 8266516fcea190fe4bd7e08521ed0ffe 397 Pfam PF02803 Thiolase, C-terminal domain 275 396 3.9E-41 T 06-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CAK77_RS17220 8266516fcea190fe4bd7e08521ed0ffe 397 SUPERFAMILY SSF53901 1 271 5.9E-75 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS17220 8266516fcea190fe4bd7e08521ed0ffe 397 Gene3D G3DSA:3.40.47.10 281 396 2.1E-53 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS17220 8266516fcea190fe4bd7e08521ed0ffe 397 Gene3D G3DSA:3.40.47.10 150 187 2.1E-53 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS17220 8266516fcea190fe4bd7e08521ed0ffe 397 Pfam PF00108 Thiolase, N-terminal domain 5 266 1.4E-69 T 06-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CAK77_RS17220 8266516fcea190fe4bd7e08521ed0ffe 397 Gene3D G3DSA:3.40.47.10 3 126 1.5E-66 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS17220 8266516fcea190fe4bd7e08521ed0ffe 397 Gene3D G3DSA:3.40.47.10 188 280 1.5E-66 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS17220 8266516fcea190fe4bd7e08521ed0ffe 397 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 395 2.8E-139 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 CAK77_RS10625 049a37c88b61f346870c6dcbac797d7d 414 Gene3D G3DSA:3.40.50.2000 208 383 1.4E-13 T 06-07-2017 CAK77_RS10625 049a37c88b61f346870c6dcbac797d7d 414 Pfam PF13439 Glycosyltransferase Family 4 15 219 3.2E-21 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 CAK77_RS10625 049a37c88b61f346870c6dcbac797d7d 414 Pfam PF00534 Glycosyl transferases group 1 230 382 7.1E-16 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 CAK77_RS10625 049a37c88b61f346870c6dcbac797d7d 414 SUPERFAMILY SSF53756 3 410 2.1E-52 T 06-07-2017 CAK77_RS17405 da9e38eccf056808a78389d2803a7ceb 229 SUPERFAMILY SSF52540 1 220 3.69E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS17405 da9e38eccf056808a78389d2803a7ceb 229 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK77_RS17405 da9e38eccf056808a78389d2803a7ceb 229 Gene3D G3DSA:3.40.50.300 2 219 5.2E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS17405 da9e38eccf056808a78389d2803a7ceb 229 SMART SM00382 28 215 5.9E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS17405 da9e38eccf056808a78389d2803a7ceb 229 Pfam PF00005 ABC transporter 19 166 7.6E-34 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK77_RS17405 da9e38eccf056808a78389d2803a7ceb 229 TIGRFAM TIGR02673 FtsE: cell division ATP-binding protein FtsE 1 214 8.0E-86 T 06-07-2017 IPR005286 Cell division protein FtsE, ATP-binding GO:0005524|GO:0051301 CAK77_RS07275 137a1d4fab9f4774cea79523d5df434a 448 Gene3D G3DSA:1.20.5.620 60 118 4.5E-8 T 06-07-2017 IPR028987 F-type ATP synthase subunit B-like, membrane domain CAK77_RS07275 137a1d4fab9f4774cea79523d5df434a 448 Gene3D G3DSA:1.10.520.20 283 350 3.6E-6 T 06-07-2017 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210 CAK77_RS07275 137a1d4fab9f4774cea79523d5df434a 448 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 283 443 1.2E-17 T 06-07-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 CAK77_RS07275 137a1d4fab9f4774cea79523d5df434a 448 Pfam PF00213 ATP synthase delta (OSCP) subunit 283 441 1.1E-26 T 06-07-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 CAK77_RS07275 137a1d4fab9f4774cea79523d5df434a 448 Hamap MF_01416 ATP synthase subunit delta [atpD]. 272 448 12.996 T 06-07-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 CAK77_RS07275 137a1d4fab9f4774cea79523d5df434a 448 PRINTS PR00125 ATP synthase delta subunit signature 406 421 2.2E-8 T 06-07-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 CAK77_RS07275 137a1d4fab9f4774cea79523d5df434a 448 PRINTS PR00125 ATP synthase delta subunit signature 421 439 2.2E-8 T 06-07-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 CAK77_RS07275 137a1d4fab9f4774cea79523d5df434a 448 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 7 154 7.6E-20 T 06-07-2017 IPR005864 ATPase, F0 complex, subunit B, bacterial GO:0015078|GO:0015986|GO:0045263 CAK77_RS07275 137a1d4fab9f4774cea79523d5df434a 448 ProSitePatterns PS00389 ATP synthase delta (OSCP) subunit signature. 408 427 - T 06-07-2017 IPR020781 ATPase, OSCP/delta subunit, conserved site GO:0015986|GO:0016020|GO:0046933 Reactome: R-HSA-163210 CAK77_RS07275 137a1d4fab9f4774cea79523d5df434a 448 Pfam PF00430 ATP synthase B/B' CF(0) 3 132 1.3E-21 T 06-07-2017 IPR002146 ATPase, F0 complex, subunit B/B', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 CAK77_RS07275 137a1d4fab9f4774cea79523d5df434a 448 SUPERFAMILY SSF47928 283 348 7.72E-5 T 06-07-2017 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210 CAK77_RS07275 137a1d4fab9f4774cea79523d5df434a 448 SUPERFAMILY SSF81573 60 118 5.89E-9 T 06-07-2017 IPR028987 F-type ATP synthase subunit B-like, membrane domain CAK77_RS07275 137a1d4fab9f4774cea79523d5df434a 448 Hamap MF_01398 ATP synthase subunit b [atpF]. 1 154 10.331 T 06-07-2017 IPR002146 ATPase, F0 complex, subunit B/B', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 CAK77_RS13120 ef27a79e53ca57d9d35d96b304fe0091 451 SUPERFAMILY SSF53474 336 403 1.61E-17 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS13120 ef27a79e53ca57d9d35d96b304fe0091 451 SUPERFAMILY SSF53474 146 249 1.61E-17 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS13120 ef27a79e53ca57d9d35d96b304fe0091 451 Gene3D G3DSA:3.40.50.1820 104 253 7.0E-16 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS13120 ef27a79e53ca57d9d35d96b304fe0091 451 Gene3D G3DSA:3.40.50.1820 303 391 7.0E-16 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS13120 ef27a79e53ca57d9d35d96b304fe0091 451 PIRSF PIRSF029171 9 417 4.2E-32 T 06-07-2017 IPR005152 Lipase, secreted GO:0004806|GO:0016042 KEGG: 00561+3.1.1.3|MetaCyc: PWY-6857 CAK77_RS13120 ef27a79e53ca57d9d35d96b304fe0091 451 Pfam PF03583 Secretory lipase 139 414 4.1E-79 T 06-07-2017 IPR005152 Lipase, secreted GO:0004806|GO:0016042 KEGG: 00561+3.1.1.3|MetaCyc: PWY-6857 CAK77_RS11920 e2b960fdfee8d135db52857641d5a3bf 259 Gene3D G3DSA:3.40.50.1110 3 254 2.8E-48 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAK77_RS11920 e2b960fdfee8d135db52857641d5a3bf 259 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 7 243 8.5E-23 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAK77_RS11920 e2b960fdfee8d135db52857641d5a3bf 259 SUPERFAMILY SSF52266 3 255 2.0E-63 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAK77_RS10220 bf23365e3442c0e671a39a033e8fc60d 173 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 38 169 6.2E-37 T 06-07-2017 IPR005247 YbhB/YbcL CAK77_RS10220 bf23365e3442c0e671a39a033e8fc60d 173 Gene3D G3DSA:3.90.280.10 13 172 1.7E-51 T 06-07-2017 IPR008914 Phosphatidylethanolamine-binding protein CAK77_RS10220 bf23365e3442c0e671a39a033e8fc60d 173 SUPERFAMILY SSF49777 14 171 9.29E-49 T 06-07-2017 IPR008914 Phosphatidylethanolamine-binding protein CAK77_RS10220 bf23365e3442c0e671a39a033e8fc60d 173 Pfam PF01161 Phosphatidylethanolamine-binding protein 39 170 3.7E-36 T 06-07-2017 IPR008914 Phosphatidylethanolamine-binding protein CAK77_RS20070 a75090a6bdde8535623a86573527f0a1 414 SUPERFAMILY SSF56601 288 409 1.18E-58 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK77_RS20070 a75090a6bdde8535623a86573527f0a1 414 SUPERFAMILY SSF56601 13 222 1.18E-58 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK77_RS20070 a75090a6bdde8535623a86573527f0a1 414 Gene3D G3DSA:3.40.710.10 28 390 3.7E-64 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK77_RS20070 a75090a6bdde8535623a86573527f0a1 414 Pfam PF00144 Beta-lactamase 38 391 4.3E-56 T 06-07-2017 IPR001466 Beta-lactamase-related CAK77_RS23635 2157418d21e5ce8f23e0c2df8d9499e6 206 SUPERFAMILY SSF52833 13 170 4.97E-10 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK77_RS23635 2157418d21e5ce8f23e0c2df8d9499e6 206 Gene3D G3DSA:3.40.30.10 9 169 1.8E-7 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK77_RS20425 5d7c037ec59b6888fb75d1886e2cdd32 313 Pfam PF11209 Protein of unknown function (DUF2993) 91 293 9.8E-20 T 06-07-2017 IPR021373 Protein of unknown function DUF2993 CAK77_RS20865 fc97c716194593f7248b5be48defadda 548 Gene3D G3DSA:2.30.38.10 361 430 1.9E-6 T 06-07-2017 CAK77_RS20865 fc97c716194593f7248b5be48defadda 548 Gene3D G3DSA:3.30.300.30 435 529 1.6E-26 T 06-07-2017 CAK77_RS20865 fc97c716194593f7248b5be48defadda 548 Gene3D G3DSA:3.40.50.980 175 342 3.0E-23 T 06-07-2017 CAK77_RS20865 fc97c716194593f7248b5be48defadda 548 Pfam PF00501 AMP-binding enzyme 10 430 1.8E-62 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK77_RS20865 fc97c716194593f7248b5be48defadda 548 SUPERFAMILY SSF56801 4 534 3.92E-110 T 06-07-2017 CAK77_RS20865 fc97c716194593f7248b5be48defadda 548 Gene3D G3DSA:3.40.50.980 4 174 5.2E-42 T 06-07-2017 CAK77_RS20865 fc97c716194593f7248b5be48defadda 548 Pfam PF13193 AMP-binding enzyme C-terminal domain 446 521 4.7E-17 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAK77_RS20865 fc97c716194593f7248b5be48defadda 548 ProSitePatterns PS00455 Putative AMP-binding domain signature. 169 180 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK77_RS19265 2bcb40202feba4a6b87e6599b5e87080 544 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 280 436 3.1E-28 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS19265 2bcb40202feba4a6b87e6599b5e87080 544 SUPERFAMILY SSF56645 53 289 4.19E-37 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK77_RS19265 2bcb40202feba4a6b87e6599b5e87080 544 Gene3D G3DSA:2.40.110.10 176 271 8.6E-22 T 06-07-2017 CAK77_RS19265 2bcb40202feba4a6b87e6599b5e87080 544 Gene3D G3DSA:1.20.140.10 272 440 7.9E-38 T 06-07-2017 CAK77_RS19265 2bcb40202feba4a6b87e6599b5e87080 544 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 176 270 1.1E-15 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAK77_RS19265 2bcb40202feba4a6b87e6599b5e87080 544 SUPERFAMILY SSF47203 284 439 1.06E-38 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS19265 2bcb40202feba4a6b87e6599b5e87080 544 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 395 414 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CAK77_RS22235 a121aafe4ac1855c54ad0493a4429312 408 SUPERFAMILY SSF88659 101 160 1.94E-9 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS22235 a121aafe4ac1855c54ad0493a4429312 408 Pfam PF04542 Sigma-70 region 2 13 77 1.5E-9 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS22235 a121aafe4ac1855c54ad0493a4429312 408 Gene3D G3DSA:1.10.1740.10 6 96 2.1E-11 T 06-07-2017 CAK77_RS22235 a121aafe4ac1855c54ad0493a4429312 408 Pfam PF08281 Sigma-70, region 4 108 159 2.8E-8 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS22235 a121aafe4ac1855c54ad0493a4429312 408 Gene3D G3DSA:1.10.10.10 102 161 4.4E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS22235 a121aafe4ac1855c54ad0493a4429312 408 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 10 160 3.2E-14 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS22235 a121aafe4ac1855c54ad0493a4429312 408 Gene3D G3DSA:1.25.40.10 207 241 8.9E-5 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK77_RS22235 a121aafe4ac1855c54ad0493a4429312 408 Gene3D G3DSA:1.25.40.10 326 390 8.9E-5 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK77_RS22235 a121aafe4ac1855c54ad0493a4429312 408 SUPERFAMILY SSF88946 6 85 3.73E-13 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS03735 d3b41c580e57a88a87e4ac268205ac99 213 Pfam PF13460 NAD(P)H-binding 8 190 1.4E-52 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS03735 d3b41c580e57a88a87e4ac268205ac99 213 SUPERFAMILY SSF51735 1 191 7.13E-34 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS03735 d3b41c580e57a88a87e4ac268205ac99 213 Gene3D G3DSA:3.40.50.720 1 191 4.2E-39 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS13665 36658e6e36a5e8376707f5bb8abe53a9 160 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 18 150 1.1E-37 T 06-07-2017 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CAK77_RS13665 36658e6e36a5e8376707f5bb8abe53a9 160 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 17 150 1.5E-45 T 06-07-2017 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CAK77_RS13665 36658e6e36a5e8376707f5bb8abe53a9 160 Gene3D G3DSA:3.40.50.960 13 156 9.8E-53 T 06-07-2017 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CAK77_RS13665 36658e6e36a5e8376707f5bb8abe53a9 160 SUPERFAMILY SSF52121 12 157 3.53E-50 T 06-07-2017 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CAK77_RS13665 36658e6e36a5e8376707f5bb8abe53a9 160 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 12 155 25.661 T 06-07-2017 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CAK77_RS22125 feb57fd0436673713a6027c3ce466fb9 189 Pfam PF04978 Protein of unknown function (DUF664) 15 163 5.2E-41 T 06-07-2017 IPR007061 Protein of unknown function DUF664 CAK77_RS22125 feb57fd0436673713a6027c3ce466fb9 189 SUPERFAMILY SSF109854 2 162 5.34E-35 T 06-07-2017 CAK77_RS22125 feb57fd0436673713a6027c3ce466fb9 189 Gene3D G3DSA:1.20.120.450 5 165 6.3E-32 T 06-07-2017 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase CAK77_RS11185 f3c352f06d445543a5d2e191f9664031 221 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 35 2.8E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS11185 f3c352f06d445543a5d2e191f9664031 221 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 66 2.8E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS11185 f3c352f06d445543a5d2e191f9664031 221 SUPERFAMILY SSF46689 11 85 4.16E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS11185 f3c352f06d445543a5d2e191f9664031 221 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 66 5.6E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS11185 f3c352f06d445543a5d2e191f9664031 221 Gene3D G3DSA:1.10.357.10 9 185 8.9E-20 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS08185 4ee8028df6ee526bc1d70caabb93fe7d 204 Pfam PF06078 Bacterial protein of unknown function (DUF937) 9 129 4.5E-17 T 06-07-2017 IPR009282 Protein of unknown function DUF937 CAK77_RS19035 648c28bfa1b0a3ed941f60ddac6a2114 277 Gene3D G3DSA:3.30.1140.32 107 206 3.1E-42 T 06-07-2017 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK77_RS19035 648c28bfa1b0a3ed941f60ddac6a2114 277 SMART SM00322 59 124 2.0E-7 T 06-07-2017 IPR004087 K Homology domain GO:0003676 CAK77_RS19035 648c28bfa1b0a3ed941f60ddac6a2114 277 ProSitePatterns PS00548 Ribosomal protein S3 signature. 163 197 - T 06-07-2017 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK77_RS19035 648c28bfa1b0a3ed941f60ddac6a2114 277 Pfam PF00189 Ribosomal protein S3, C-terminal domain 119 202 1.1E-36 T 06-07-2017 CAK77_RS19035 648c28bfa1b0a3ed941f60ddac6a2114 277 SUPERFAMILY SSF54814 2 105 2.15E-36 T 06-07-2017 IPR009019 K homology domain, prokaryotic type GO:0003723 CAK77_RS19035 648c28bfa1b0a3ed941f60ddac6a2114 277 SUPERFAMILY SSF54821 106 206 3.01E-36 T 06-07-2017 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK77_RS19035 648c28bfa1b0a3ed941f60ddac6a2114 277 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 209 7.3E-94 T 06-07-2017 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 CAK77_RS19035 648c28bfa1b0a3ed941f60ddac6a2114 277 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 206 38.181 T 06-07-2017 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 CAK77_RS19035 648c28bfa1b0a3ed941f60ddac6a2114 277 Gene3D G3DSA:3.30.300.20 17 106 9.3E-33 T 06-07-2017 IPR015946 K homology domain-like, alpha/beta CAK77_RS19035 648c28bfa1b0a3ed941f60ddac6a2114 277 Pfam PF07650 KH domain 38 109 5.7E-19 T 06-07-2017 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK77_RS05315 42e5bd4bc9a29ee99bfd21296f573874 300 Pfam PF00549 CoA-ligase 163 280 5.1E-15 T 06-07-2017 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CAK77_RS05315 42e5bd4bc9a29ee99bfd21296f573874 300 PRINTS PR01798 Succinyl-CoA synthase signature 91 108 9.6E-35 T 06-07-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 CAK77_RS05315 42e5bd4bc9a29ee99bfd21296f573874 300 PRINTS PR01798 Succinyl-CoA synthase signature 249 266 9.6E-35 T 06-07-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 CAK77_RS05315 42e5bd4bc9a29ee99bfd21296f573874 300 PRINTS PR01798 Succinyl-CoA synthase signature 186 204 9.6E-35 T 06-07-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 CAK77_RS05315 42e5bd4bc9a29ee99bfd21296f573874 300 PRINTS PR01798 Succinyl-CoA synthase signature 217 230 9.6E-35 T 06-07-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 CAK77_RS05315 42e5bd4bc9a29ee99bfd21296f573874 300 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 245 258 - T 06-07-2017 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site CAK77_RS05315 42e5bd4bc9a29ee99bfd21296f573874 300 Gene3D G3DSA:3.40.50.720 2 130 1.4E-46 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS05315 42e5bd4bc9a29ee99bfd21296f573874 300 PIRSF PIRSF001553 1 300 5.8E-118 T 06-07-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 CAK77_RS05315 42e5bd4bc9a29ee99bfd21296f573874 300 SUPERFAMILY SSF51735 1 133 1.06E-34 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS05315 42e5bd4bc9a29ee99bfd21296f573874 300 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 163 190 - T 06-07-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 CAK77_RS05315 42e5bd4bc9a29ee99bfd21296f573874 300 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 3 297 1.3E-128 T 06-07-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 CAK77_RS05315 42e5bd4bc9a29ee99bfd21296f573874 300 Gene3D G3DSA:3.40.50.261 131 296 2.0E-65 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CAK77_RS05315 42e5bd4bc9a29ee99bfd21296f573874 300 SMART SM00881 4 109 1.5E-27 T 06-07-2017 IPR003781 CoA-binding GO:0048037 CAK77_RS05315 42e5bd4bc9a29ee99bfd21296f573874 300 Pfam PF02629 CoA binding domain 6 108 6.7E-24 T 06-07-2017 IPR003781 CoA-binding GO:0048037 CAK77_RS05315 42e5bd4bc9a29ee99bfd21296f573874 300 SUPERFAMILY SSF52210 134 296 1.57E-46 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CAK77_RS06845 cfa6d5156ec98167c83f02591421ea1f 427 Pfam PF13406 Transglycosylase SLT domain 198 245 6.8E-10 T 06-07-2017 IPR031304 Transglycosylase SLT domain 2 CAK77_RS06845 cfa6d5156ec98167c83f02591421ea1f 427 SUPERFAMILY SSF53955 112 281 5.34E-38 T 06-07-2017 IPR023346 Lysozyme-like domain CAK77_RS06845 cfa6d5156ec98167c83f02591421ea1f 427 Gene3D G3DSA:1.10.530.10 124 163 8.2E-11 T 06-07-2017 CAK77_RS06845 cfa6d5156ec98167c83f02591421ea1f 427 Gene3D G3DSA:1.10.530.10 201 263 8.2E-11 T 06-07-2017 CAK77_RS16365 beea93dbcd2a91787a82ae1c21892125 370 PIRSF PIRSF001434 3 368 1.8E-100 T 06-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CAK77_RS16365 beea93dbcd2a91787a82ae1c21892125 370 SUPERFAMILY SSF53383 20 366 8.81E-76 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK77_RS16365 beea93dbcd2a91787a82ae1c21892125 370 Gene3D G3DSA:3.40.640.10 30 244 6.8E-61 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK77_RS16365 beea93dbcd2a91787a82ae1c21892125 370 Gene3D G3DSA:3.90.1150.10 247 367 6.1E-29 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK77_RS16365 beea93dbcd2a91787a82ae1c21892125 370 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 42 365 3.9E-81 T 06-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CAK77_RS05390 0599a59ab85def93f1c4a2a3747c7807 385 SUPERFAMILY SSF47203 231 381 4.67E-40 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS05390 0599a59ab85def93f1c4a2a3747c7807 385 Gene3D G3DSA:1.20.140.10 220 381 3.3E-53 T 06-07-2017 CAK77_RS05390 0599a59ab85def93f1c4a2a3747c7807 385 Gene3D G3DSA:1.10.540.10 8 123 7.4E-27 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS05390 0599a59ab85def93f1c4a2a3747c7807 385 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 122 4.2E-24 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS05390 0599a59ab85def93f1c4a2a3747c7807 385 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 340 359 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CAK77_RS05390 0599a59ab85def93f1c4a2a3747c7807 385 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 126 220 5.9E-25 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAK77_RS05390 0599a59ab85def93f1c4a2a3747c7807 385 SUPERFAMILY SSF56645 4 240 2.23E-74 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK77_RS05390 0599a59ab85def93f1c4a2a3747c7807 385 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 232 379 9.7E-40 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS05390 0599a59ab85def93f1c4a2a3747c7807 385 Gene3D G3DSA:2.40.110.10 126 219 1.1E-38 T 06-07-2017 CAK77_RS17215 9182d584780d485a7c2e9dd72bd039f4 488 Pfam PF13810 Domain of unknown function (DUF4185) 161 484 2.8E-111 T 06-07-2017 IPR025442 Domain of unknown function DUF4185 CAK77_RS13690 cde97c4b9f17db297f63f8e72ad00a31 246 SUPERFAMILY SSF56959 73 244 2.16E-33 T 06-07-2017 IPR016183 Leukocidin/porin GO:0005576|GO:0051715 CAK77_RS13690 cde97c4b9f17db297f63f8e72ad00a31 246 Gene3D G3DSA:2.60.40.1650 72 142 3.4E-48 T 06-07-2017 CAK77_RS13690 cde97c4b9f17db297f63f8e72ad00a31 246 Gene3D G3DSA:2.60.40.1650 184 245 3.4E-48 T 06-07-2017 CAK77_RS13690 cde97c4b9f17db297f63f8e72ad00a31 246 Pfam PF09203 MspA 82 244 1.8E-50 T 06-07-2017 IPR015286 Porin family, mycobacterial-type CAK77_RS19425 41522963476b40c3d19b2c3b31e99d4b 216 Gene3D G3DSA:1.10.10.10 148 206 1.4E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS19425 41522963476b40c3d19b2c3b31e99d4b 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 180 9.7E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK77_RS19425 41522963476b40c3d19b2c3b31e99d4b 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 192 9.7E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK77_RS19425 41522963476b40c3d19b2c3b31e99d4b 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 164 9.7E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK77_RS19425 41522963476b40c3d19b2c3b31e99d4b 216 SMART SM00448 2 115 2.2E-29 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK77_RS19425 41522963476b40c3d19b2c3b31e99d4b 216 Pfam PF00196 Bacterial regulatory proteins, luxR family 150 204 2.8E-16 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK77_RS19425 41522963476b40c3d19b2c3b31e99d4b 216 ProSitePatterns PS00622 LuxR-type HTH domain signature. 164 191 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK77_RS19425 41522963476b40c3d19b2c3b31e99d4b 216 Gene3D G3DSA:3.40.50.2300 1 147 1.3E-34 T 06-07-2017 CAK77_RS19425 41522963476b40c3d19b2c3b31e99d4b 216 SMART SM00421 147 204 1.1E-21 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK77_RS19425 41522963476b40c3d19b2c3b31e99d4b 216 SUPERFAMILY SSF52172 1 181 1.32E-32 T 06-07-2017 IPR011006 CheY-like superfamily CAK77_RS19425 41522963476b40c3d19b2c3b31e99d4b 216 Pfam PF00072 Response regulator receiver domain 4 115 7.9E-26 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK77_RS05330 7c51d2cc07b0e688396f68a3ac55d0aa 373 SUPERFAMILY SSF51679 8 355 3.01E-82 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS05330 7c51d2cc07b0e688396f68a3ac55d0aa 373 Pfam PF00296 Luciferase-like monooxygenase 11 328 2.8E-69 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS05330 7c51d2cc07b0e688396f68a3ac55d0aa 373 Gene3D G3DSA:3.20.20.30 8 358 2.7E-93 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS05330 7c51d2cc07b0e688396f68a3ac55d0aa 373 TIGRFAM TIGR04021 LLM_DMSO2_sfnG: dimethyl sulfone monooxygenase SfnG 10 357 8.8E-190 T 06-07-2017 IPR024014 Dimethyl sulphone monooxygenase SfnG CAK77_RS11440 5a0911823cca26c38b3d14c2155c12ff 67 Gene3D G3DSA:2.20.25.10 10 64 7.4E-15 T 06-07-2017 CAK77_RS11440 5a0911823cca26c38b3d14c2155c12ff 67 Pfam PF03966 Trm112p-like protein 5 45 1.0E-6 T 06-07-2017 IPR005651 Uncharacterised protein family UPF0434/Trm112 CAK77_RS11440 5a0911823cca26c38b3d14c2155c12ff 67 SUPERFAMILY SSF158997 1 60 7.32E-15 T 06-07-2017 CAK77_RS15305 e068dd685ce899a34a75d3c620277809 831 Pfam PF01580 FtsK/SpoIIIE family 435 635 5.9E-64 T 06-07-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CAK77_RS15305 e068dd685ce899a34a75d3c620277809 831 SUPERFAMILY SSF46785 739 804 3.13E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS15305 e068dd685ce899a34a75d3c620277809 831 Pfam PF09397 Ftsk gamma domain 743 800 6.6E-23 T 06-07-2017 IPR018541 FtsK gamma domain CAK77_RS15305 e068dd685ce899a34a75d3c620277809 831 SUPERFAMILY SSF52540 409 705 7.97E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS15305 e068dd685ce899a34a75d3c620277809 831 Gene3D G3DSA:3.40.50.300 409 701 4.5E-83 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS15305 e068dd685ce899a34a75d3c620277809 831 Pfam PF13491 4TM region of DNA translocase FtsK/SpoIIIE 109 227 3.9E-7 T 06-07-2017 IPR025199 DNA translocase FtsK, 4TM region CAK77_RS15305 e068dd685ce899a34a75d3c620277809 831 SMART SM00843 738 803 1.2E-30 T 06-07-2017 IPR018541 FtsK gamma domain CAK77_RS16460 bd4ba3c4a75b2444ead6b838a43de746 523 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 139 166 - T 06-07-2017 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 CAK77_RS16460 bd4ba3c4a75b2444ead6b838a43de746 523 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 102 276 2.6E-62 T 06-07-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CAK77_RS16460 bd4ba3c4a75b2444ead6b838a43de746 523 SUPERFAMILY SSF52283 1 129 1.53E-35 T 06-07-2017 CAK77_RS16460 bd4ba3c4a75b2444ead6b838a43de746 523 SUPERFAMILY SSF51735 95 276 5.02E-60 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS16460 bd4ba3c4a75b2444ead6b838a43de746 523 SUPERFAMILY SSF143548 315 444 6.8E-31 T 06-07-2017 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 CAK77_RS16460 bd4ba3c4a75b2444ead6b838a43de746 523 Gene3D G3DSA:3.40.50.720 1 103 1.9E-35 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS16460 bd4ba3c4a75b2444ead6b838a43de746 523 TIGRFAM TIGR01327 PGDH: phosphoglycerate dehydrogenase 1 522 3.2E-193 T 06-07-2017 IPR006236 D-3-phosphoglycerate dehydrogenase GO:0004617|GO:0006564 KEGG: 00260+1.1.1.95|KEGG: 00680+1.1.1.95|Reactome: R-HSA-977347 CAK77_RS16460 bd4ba3c4a75b2444ead6b838a43de746 523 Gene3D G3DSA:3.40.50.720 104 278 1.6E-69 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS16460 bd4ba3c4a75b2444ead6b838a43de746 523 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 187 209 - T 06-07-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CAK77_RS16460 bd4ba3c4a75b2444ead6b838a43de746 523 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 1 308 1.5E-34 T 06-07-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CAK77_RS16460 bd4ba3c4a75b2444ead6b838a43de746 523 Gene3D G3DSA:3.30.70.260 443 514 1.9E-13 T 06-07-2017 CAK77_RS16460 bd4ba3c4a75b2444ead6b838a43de746 523 SUPERFAMILY SSF55021 448 517 9.99E-12 T 06-07-2017 CAK77_RS16460 bd4ba3c4a75b2444ead6b838a43de746 523 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 216 232 - T 06-07-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CAK77_RS16460 bd4ba3c4a75b2444ead6b838a43de746 523 Gene3D G3DSA:3.30.1330.90 314 442 7.5E-38 T 06-07-2017 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 CAK77_RS09400 aee2487b563c3ed6ffa9288569f3e817 464 SUPERFAMILY SSF103473 236 444 3.53E-57 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK77_RS09400 aee2487b563c3ed6ffa9288569f3e817 464 SUPERFAMILY SSF103473 2 186 3.53E-57 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK77_RS09400 aee2487b563c3ed6ffa9288569f3e817 464 PRINTS PR01036 Tetracycline resistance protein TetB signature 96 116 3.4E-8 T 06-07-2017 CAK77_RS09400 aee2487b563c3ed6ffa9288569f3e817 464 PRINTS PR01036 Tetracycline resistance protein TetB signature 5 29 3.4E-8 T 06-07-2017 CAK77_RS09400 aee2487b563c3ed6ffa9288569f3e817 464 PRINTS PR01036 Tetracycline resistance protein TetB signature 382 401 3.4E-8 T 06-07-2017 CAK77_RS09400 aee2487b563c3ed6ffa9288569f3e817 464 PRINTS PR01036 Tetracycline resistance protein TetB signature 126 150 3.4E-8 T 06-07-2017 CAK77_RS09400 aee2487b563c3ed6ffa9288569f3e817 464 Gene3D G3DSA:1.20.1250.20 3 185 3.4E-29 T 06-07-2017 CAK77_RS09400 aee2487b563c3ed6ffa9288569f3e817 464 Gene3D G3DSA:1.20.1250.20 270 451 2.1E-7 T 06-07-2017 CAK77_RS09400 aee2487b563c3ed6ffa9288569f3e817 464 Pfam PF07690 Major Facilitator Superfamily 6 397 9.5E-46 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK77_RS12720 713829a4c5887f0a8e504e8ddb29a857 341 SUPERFAMILY SSF53474 27 295 2.48E-35 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS12720 713829a4c5887f0a8e504e8ddb29a857 341 Gene3D G3DSA:3.40.50.1820 76 296 2.8E-35 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS12720 713829a4c5887f0a8e504e8ddb29a857 341 Pfam PF07859 alpha/beta hydrolase fold 77 277 4.5E-28 T 06-07-2017 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CAK77_RS18225 a714890a985f762e00efcd13e19bcfb6 401 SUPERFAMILY SSF55031 177 278 1.11E-20 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAK77_RS18225 a714890a985f762e00efcd13e19bcfb6 401 Pfam PF01546 Peptidase family M20/M25/M40 95 377 9.3E-9 T 06-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CAK77_RS18225 a714890a985f762e00efcd13e19bcfb6 401 Gene3D G3DSA:3.30.70.360 177 278 2.6E-23 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAK77_RS18225 a714890a985f762e00efcd13e19bcfb6 401 Pfam PF07687 Peptidase dimerisation domain 176 265 1.8E-7 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAK77_RS18225 a714890a985f762e00efcd13e19bcfb6 401 PIRSF PIRSF037226 7 401 2.3E-143 T 06-07-2017 IPR017144 Peptidase M20A, amidohydrolase, predicted CAK77_RS18225 a714890a985f762e00efcd13e19bcfb6 401 SUPERFAMILY SSF53187 288 383 1.44E-59 T 06-07-2017 CAK77_RS18225 a714890a985f762e00efcd13e19bcfb6 401 SUPERFAMILY SSF53187 17 188 1.44E-59 T 06-07-2017 CAK77_RS18225 a714890a985f762e00efcd13e19bcfb6 401 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 28 354 2.5E-58 T 06-07-2017 IPR017439 Amidohydrolase GO:0016787 CAK77_RS18225 a714890a985f762e00efcd13e19bcfb6 401 Gene3D G3DSA:3.40.630.10 11 176 5.9E-63 T 06-07-2017 CAK77_RS18225 a714890a985f762e00efcd13e19bcfb6 401 Gene3D G3DSA:3.40.630.10 285 390 5.9E-63 T 06-07-2017 CAK77_RS07625 001bea6969d442614a6a2389bf6e2a0f 161 ProSitePatterns PS00893 Nudix box signature. 50 71 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CAK77_RS07625 001bea6969d442614a6a2389bf6e2a0f 161 Gene3D G3DSA:3.90.79.10 10 143 1.9E-29 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAK77_RS07625 001bea6969d442614a6a2389bf6e2a0f 161 Pfam PF00293 NUDIX domain 25 137 3.7E-18 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 CAK77_RS07625 001bea6969d442614a6a2389bf6e2a0f 161 SUPERFAMILY SSF55811 10 145 4.06E-30 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAK77_RS06225 e5b2a3eeeded4f0fdade75da52025f55 69 Pfam PF05532 CsbD-like 5 57 6.4E-15 T 06-07-2017 IPR008462 CsbD-like CAK77_RS06225 e5b2a3eeeded4f0fdade75da52025f55 69 SUPERFAMILY SSF69047 5 66 1.57E-9 T 06-07-2017 IPR008462 CsbD-like CAK77_RS06225 e5b2a3eeeded4f0fdade75da52025f55 69 Gene3D G3DSA:1.10.1470.10 5 66 1.7E-14 T 06-07-2017 IPR008462 CsbD-like CAK77_RS20860 23ad4b8d402760edaf8501480197b28a 371 Gene3D G3DSA:3.20.20.70 1 71 2.8E-65 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK77_RS20860 23ad4b8d402760edaf8501480197b28a 371 Gene3D G3DSA:3.20.20.70 108 352 2.8E-65 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK77_RS20860 23ad4b8d402760edaf8501480197b28a 371 SUPERFAMILY SSF51412 1 362 7.48E-51 T 06-07-2017 CAK77_RS20860 23ad4b8d402760edaf8501480197b28a 371 Pfam PF03060 Nitronate monooxygenase 11 357 2.3E-48 T 06-07-2017 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 CAK77_RS06385 b7b6f6c92cf7ffa94f0f178d8f34c43d 366 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 26 308 5.4E-42 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAK77_RS06385 b7b6f6c92cf7ffa94f0f178d8f34c43d 366 Gene3D G3DSA:3.40.50.1100 58 154 1.9E-18 T 06-07-2017 CAK77_RS06385 b7b6f6c92cf7ffa94f0f178d8f34c43d 366 Gene3D G3DSA:3.40.50.1100 155 322 7.7E-40 T 06-07-2017 CAK77_RS06385 b7b6f6c92cf7ffa94f0f178d8f34c43d 366 SUPERFAMILY SSF53686 21 329 1.14E-62 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAK77_RS06785 c5ca92552eca426019b8aecba6d7d21a 461 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 74 1.7E-17 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK77_RS06785 c5ca92552eca426019b8aecba6d7d21a 461 SMART SM00345 15 74 5.0E-17 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK77_RS06785 c5ca92552eca426019b8aecba6d7d21a 461 SUPERFAMILY SSF53383 113 452 3.02E-67 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK77_RS06785 c5ca92552eca426019b8aecba6d7d21a 461 Gene3D G3DSA:3.90.1150.10 344 452 2.2E-8 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK77_RS06785 c5ca92552eca426019b8aecba6d7d21a 461 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 1.1E-6 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK77_RS06785 c5ca92552eca426019b8aecba6d7d21a 461 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 1.1E-6 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK77_RS06785 c5ca92552eca426019b8aecba6d7d21a 461 SUPERFAMILY SSF46785 4 78 5.18E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS06785 c5ca92552eca426019b8aecba6d7d21a 461 Pfam PF00155 Aminotransferase class I and II 132 414 3.4E-18 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAK77_RS06785 c5ca92552eca426019b8aecba6d7d21a 461 Gene3D G3DSA:3.40.640.10 132 343 8.7E-45 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK77_RS06785 c5ca92552eca426019b8aecba6d7d21a 461 Gene3D G3DSA:1.10.10.10 2 75 6.0E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS22945 fdc95b8fd9ccc33c6650ad5390c28753 267 SUPERFAMILY SSF53335 15 252 7.33E-59 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS22945 fdc95b8fd9ccc33c6650ad5390c28753 267 Pfam PF04072 Leucine carboxyl methyltransferase 22 181 1.7E-25 T 06-07-2017 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 CAK77_RS22945 fdc95b8fd9ccc33c6650ad5390c28753 267 Gene3D G3DSA:3.40.50.150 18 198 7.5E-40 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS20985 91cac858f954159fc4a5b14dfbbd46cf 197 Gene3D G3DSA:3.90.45.10 5 193 2.8E-55 T 06-07-2017 IPR023635 Peptide deformylase CAK77_RS20985 91cac858f954159fc4a5b14dfbbd46cf 197 Pfam PF01327 Polypeptide deformylase 5 163 1.8E-37 T 06-07-2017 IPR023635 Peptide deformylase CAK77_RS20985 91cac858f954159fc4a5b14dfbbd46cf 197 SUPERFAMILY SSF56420 3 188 8.51E-49 T 06-07-2017 IPR023635 Peptide deformylase CAK77_RS20985 91cac858f954159fc4a5b14dfbbd46cf 197 PRINTS PR01576 Peptide deformylase signature 104 115 7.2E-30 T 06-07-2017 IPR023635 Peptide deformylase CAK77_RS20985 91cac858f954159fc4a5b14dfbbd46cf 197 PRINTS PR01576 Peptide deformylase signature 38 67 7.2E-30 T 06-07-2017 IPR023635 Peptide deformylase CAK77_RS20985 91cac858f954159fc4a5b14dfbbd46cf 197 PRINTS PR01576 Peptide deformylase signature 116 134 7.2E-30 T 06-07-2017 IPR023635 Peptide deformylase CAK77_RS20985 91cac858f954159fc4a5b14dfbbd46cf 197 PRINTS PR01576 Peptide deformylase signature 135 164 7.2E-30 T 06-07-2017 IPR023635 Peptide deformylase CAK77_RS20985 91cac858f954159fc4a5b14dfbbd46cf 197 Hamap MF_00163 Peptide deformylase [def]. 2 177 26.224 T 06-07-2017 IPR023635 Peptide deformylase CAK77_RS20985 91cac858f954159fc4a5b14dfbbd46cf 197 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 28 171 5.2E-32 T 06-07-2017 IPR023635 Peptide deformylase CAK77_RS20985 91cac858f954159fc4a5b14dfbbd46cf 197 PIRSF PIRSF004749 1 182 2.4E-36 T 06-07-2017 IPR023635 Peptide deformylase CAK77_RS15455 620fa9b5033fd3a063527e155b8ebf2d 416 Gene3D G3DSA:3.30.830.10 1 196 8.7E-58 T 06-07-2017 IPR011237 Peptidase M16 domain GO:0046872 CAK77_RS15455 620fa9b5033fd3a063527e155b8ebf2d 416 Pfam PF05193 Peptidase M16 inactive domain 154 331 1.3E-42 T 06-07-2017 IPR007863 Peptidase M16, C-terminal CAK77_RS15455 620fa9b5033fd3a063527e155b8ebf2d 416 Gene3D G3DSA:3.30.830.10 222 398 4.1E-47 T 06-07-2017 IPR011237 Peptidase M16 domain GO:0046872 CAK77_RS15455 620fa9b5033fd3a063527e155b8ebf2d 416 SUPERFAMILY SSF63411 1 198 2.2E-53 T 06-07-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CAK77_RS15455 620fa9b5033fd3a063527e155b8ebf2d 416 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 21 44 - T 06-07-2017 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 CAK77_RS15455 620fa9b5033fd3a063527e155b8ebf2d 416 Pfam PF00675 Insulinase (Peptidase family M16) 1 146 9.5E-35 T 06-07-2017 IPR011765 Peptidase M16, N-terminal CAK77_RS15455 620fa9b5033fd3a063527e155b8ebf2d 416 SUPERFAMILY SSF63411 216 399 9.0E-46 T 06-07-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CAK77_RS01885 3acedfb726dca393069c809c750fd6e5 491 SUPERFAMILY SSF55931 310 455 8.63E-47 T 06-07-2017 CAK77_RS01885 3acedfb726dca393069c809c750fd6e5 491 SUPERFAMILY SSF55931 37 279 8.63E-47 T 06-07-2017 CAK77_RS01885 3acedfb726dca393069c809c750fd6e5 491 PIRSF PIRSF012666 1 491 1.7E-226 T 06-07-2017 IPR016602 Uncharacterised conserved protein UCP012666 CAK77_RS01885 3acedfb726dca393069c809c750fd6e5 491 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 188 248 2.6E-5 T 06-07-2017 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CAK77_RS11955 b20240eae8e1f923fdb185d5f92782f2 235 SMART SM00382 23 199 1.9E-16 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS11955 b20240eae8e1f923fdb185d5f92782f2 235 Gene3D G3DSA:3.40.50.300 2 204 7.2E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS11955 b20240eae8e1f923fdb185d5f92782f2 235 SUPERFAMILY SSF52540 5 204 4.11E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS11955 b20240eae8e1f923fdb185d5f92782f2 235 Pfam PF00005 ABC transporter 15 150 2.3E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK77_RS11955 b20240eae8e1f923fdb185d5f92782f2 235 ProSitePatterns PS00211 ABC transporters family signature. 123 137 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK77_RS18850 700ec52495d02f0d25d7a3e87a60cd4e 274 TIGRFAM TIGR03620 F420_MSMEG_4141: probable F420-dependent oxidoreductase, MSMEG_4141 family 8 272 8.6E-111 T 06-07-2017 IPR019922 Luciferase-like, F420-dependent oxidoreductase, MSMEG4141, predicted CAK77_RS18850 700ec52495d02f0d25d7a3e87a60cd4e 274 Pfam PF00296 Luciferase-like monooxygenase 19 116 4.8E-12 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS18850 700ec52495d02f0d25d7a3e87a60cd4e 274 SUPERFAMILY SSF51679 18 271 3.2E-33 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS18850 700ec52495d02f0d25d7a3e87a60cd4e 274 Gene3D G3DSA:3.20.20.30 20 119 1.1E-12 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS18850 700ec52495d02f0d25d7a3e87a60cd4e 274 Gene3D G3DSA:3.20.20.30 129 259 1.8E-9 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS21600 18776dcc3a949ef829e02fe054634918 1010 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 374 385 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CAK77_RS21600 18776dcc3a949ef829e02fe054634918 1010 SUPERFAMILY SSF46548 358 402 7.5E-21 T 06-07-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 CAK77_RS21600 18776dcc3a949ef829e02fe054634918 1010 SUPERFAMILY SSF46548 270 329 7.5E-21 T 06-07-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 CAK77_RS21600 18776dcc3a949ef829e02fe054634918 1010 Pfam PF02754 Cysteine-rich domain 459 550 2.2E-15 T 06-07-2017 IPR004017 Cysteine-rich domain CAK77_RS21600 18776dcc3a949ef829e02fe054634918 1010 Pfam PF02754 Cysteine-rich domain 589 675 5.5E-16 T 06-07-2017 IPR004017 Cysteine-rich domain CAK77_RS21600 18776dcc3a949ef829e02fe054634918 1010 Pfam PF13183 4Fe-4S dicluster domain 295 388 3.7E-14 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CAK77_RS21600 18776dcc3a949ef829e02fe054634918 1010 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 298 309 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CAK77_RS21600 18776dcc3a949ef829e02fe054634918 1010 Gene3D G3DSA:1.10.1060.10 271 402 1.4E-31 T 06-07-2017 CAK77_RS00310 f6062b42c70e8eea8019d328a71ffe9c 87 Pfam PF06781 Uncharacterised protein family (UPF0233) 1 87 4.5E-32 T 06-07-2017 IPR009619 Cell division protein CrgA CAK77_RS00310 f6062b42c70e8eea8019d328a71ffe9c 87 Hamap MF_00631 Cell division protein CrgA [crgA]. 1 87 21.242 T 06-07-2017 IPR009619 Cell division protein CrgA CAK77_RS06155 4e859fd2edeca842e1c2028530d0d130 386 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 30 380 3.0E-105 T 06-07-2017 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 CAK77_RS06155 4e859fd2edeca842e1c2028530d0d130 386 SUPERFAMILY SSF54631 266 380 7.08E-7 T 06-07-2017 CAK77_RS06155 4e859fd2edeca842e1c2028530d0d130 386 SUPERFAMILY SSF52540 16 256 6.33E-77 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS06155 4e859fd2edeca842e1c2028530d0d130 386 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK77_RS06155 4e859fd2edeca842e1c2028530d0d130 386 SMART SM00382 42 238 4.6E-21 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS06155 4e859fd2edeca842e1c2028530d0d130 386 Pfam PF00005 ABC transporter 33 179 2.4E-34 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK77_RS06155 4e859fd2edeca842e1c2028530d0d130 386 Gene3D G3DSA:3.40.50.300 14 254 2.7E-77 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS06155 4e859fd2edeca842e1c2028530d0d130 386 Gene3D G3DSA:3.10.580.10 264 380 2.7E-6 T 06-07-2017 CAK77_RS10605 0ef820dd8e8c7ca1ffe917f510128511 269 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK77_RS10605 0ef820dd8e8c7ca1ffe917f510128511 269 Gene3D G3DSA:3.40.50.300 12 229 1.5E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS10605 0ef820dd8e8c7ca1ffe917f510128511 269 SUPERFAMILY SSF52540 19 227 2.3E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS10605 0ef820dd8e8c7ca1ffe917f510128511 269 Pfam PF00005 ABC transporter 40 177 3.2E-28 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK77_RS10605 0ef820dd8e8c7ca1ffe917f510128511 269 SMART SM00382 47 227 1.1E-18 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS17780 315e3bdc1fefca59ce3992bee1bbf905 390 Gene3D G3DSA:3.40.50.80 160 288 2.4E-22 T 06-07-2017 CAK77_RS17780 315e3bdc1fefca59ce3992bee1bbf905 390 SUPERFAMILY SSF63380 45 170 6.49E-21 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CAK77_RS17780 315e3bdc1fefca59ce3992bee1bbf905 390 Pfam PF00175 Oxidoreductase NAD-binding domain 178 280 1.1E-6 T 06-07-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CAK77_RS17780 315e3bdc1fefca59ce3992bee1bbf905 390 SUPERFAMILY SSF52343 162 300 5.63E-24 T 06-07-2017 CAK77_RS17780 315e3bdc1fefca59ce3992bee1bbf905 390 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 317 381 3.9E-9 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK77_RS17780 315e3bdc1fefca59ce3992bee1bbf905 390 SUPERFAMILY SSF54292 291 390 2.36E-20 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK77_RS17780 315e3bdc1fefca59ce3992bee1bbf905 390 PRINTS PR00406 Cytochrome B5 reductase signature 266 274 9.7E-6 T 06-07-2017 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 CAK77_RS17780 315e3bdc1fefca59ce3992bee1bbf905 390 PRINTS PR00406 Cytochrome B5 reductase signature 177 196 9.7E-6 T 06-07-2017 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 CAK77_RS17780 315e3bdc1fefca59ce3992bee1bbf905 390 PRINTS PR00406 Cytochrome B5 reductase signature 154 168 9.7E-6 T 06-07-2017 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 CAK77_RS17780 315e3bdc1fefca59ce3992bee1bbf905 390 PRINTS PR00406 Cytochrome B5 reductase signature 102 109 9.7E-6 T 06-07-2017 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 CAK77_RS17780 315e3bdc1fefca59ce3992bee1bbf905 390 Gene3D G3DSA:3.10.20.30 292 389 2.1E-20 T 06-07-2017 IPR012675 Beta-grasp domain CAK77_RS17780 315e3bdc1fefca59ce3992bee1bbf905 390 Gene3D G3DSA:2.40.30.10 53 159 2.7E-26 T 06-07-2017 CAK77_RS17780 315e3bdc1fefca59ce3992bee1bbf905 390 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 177 196 3.2E-5 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK77_RS17780 315e3bdc1fefca59ce3992bee1bbf905 390 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 83 93 3.2E-5 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK77_RS17780 315e3bdc1fefca59ce3992bee1bbf905 390 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 102 109 3.2E-5 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK77_RS08440 bbd01cdfc5e9b912befa8a615eb4bcd9 341 Pfam PF12857 TOBE-like domain 278 327 4.1E-9 T 06-07-2017 IPR024765 TOBE-like domain KEGG: 00920+3.6.3.25 CAK77_RS08440 bbd01cdfc5e9b912befa8a615eb4bcd9 341 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK77_RS08440 bbd01cdfc5e9b912befa8a615eb4bcd9 341 Gene3D G3DSA:3.40.50.300 4 237 1.2E-84 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS08440 bbd01cdfc5e9b912befa8a615eb4bcd9 341 TIGRFAM TIGR00968 3a0106s01: sulfate ABC transporter, ATP-binding protein 7 243 9.8E-126 T 06-07-2017 IPR005666 Sulphate transport system permease protein 1 GO:0006810|GO:0016020|GO:0042626 KEGG: 00920+3.6.3.25 CAK77_RS08440 bbd01cdfc5e9b912befa8a615eb4bcd9 341 Gene3D G3DSA:2.40.50.100 277 326 4.6E-7 T 06-07-2017 CAK77_RS08440 bbd01cdfc5e9b912befa8a615eb4bcd9 341 SMART SM00382 31 214 1.1E-18 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS08440 bbd01cdfc5e9b912befa8a615eb4bcd9 341 Pfam PF00005 ABC transporter 22 164 4.3E-37 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK77_RS08440 bbd01cdfc5e9b912befa8a615eb4bcd9 341 SUPERFAMILY SSF50331 246 327 2.98E-9 T 06-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal CAK77_RS08440 bbd01cdfc5e9b912befa8a615eb4bcd9 341 SUPERFAMILY SSF52540 7 241 1.46E-87 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS13410 e4312c937b7a6870882090d1291f3fa7 269 Pfam PF00378 Enoyl-CoA hydratase/isomerase 13 267 7.7E-46 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAK77_RS13410 e4312c937b7a6870882090d1291f3fa7 269 SUPERFAMILY SSF52096 2 267 2.49E-69 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS13410 e4312c937b7a6870882090d1291f3fa7 269 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 106 126 - T 06-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CAK77_RS13410 e4312c937b7a6870882090d1291f3fa7 269 Gene3D G3DSA:3.90.226.10 3 262 1.5E-67 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS19935 2fcd041c134014dd0c50563ee077c021 129 Pfam PF04075 Domain of unknown function (DUF385) 27 94 2.2E-11 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CAK77_RS19935 2fcd041c134014dd0c50563ee077c021 129 Gene3D G3DSA:2.30.110.10 30 116 2.3E-9 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS19935 2fcd041c134014dd0c50563ee077c021 129 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 26 101 3.3E-14 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CAK77_RS19935 2fcd041c134014dd0c50563ee077c021 129 SUPERFAMILY SSF50475 32 128 6.96E-11 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS06870 4d798f4297dc64d38aa6bbdf31bfb68a 474 Gene3D G3DSA:3.40.190.10 84 170 2.8E-13 T 06-07-2017 CAK77_RS06870 4d798f4297dc64d38aa6bbdf31bfb68a 474 SUPERFAMILY SSF53850 40 295 9.93E-61 T 06-07-2017 CAK77_RS06870 4d798f4297dc64d38aa6bbdf31bfb68a 474 SUPERFAMILY SSF53850 337 445 9.93E-61 T 06-07-2017 CAK77_RS06870 4d798f4297dc64d38aa6bbdf31bfb68a 474 Gene3D G3DSA:3.40.190.10 171 295 1.1E-49 T 06-07-2017 CAK77_RS06870 4d798f4297dc64d38aa6bbdf31bfb68a 474 Gene3D G3DSA:3.40.190.10 337 396 1.1E-49 T 06-07-2017 CAK77_RS06870 4d798f4297dc64d38aa6bbdf31bfb68a 474 Pfam PF01547 Bacterial extracellular solute-binding protein 85 386 7.7E-33 T 06-07-2017 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 CAK77_RS21060 737eb4b4d472102c085bed0595441daf 505 Pfam PF13556 PucR C-terminal helix-turn-helix domain 440 496 2.6E-13 T 06-07-2017 IPR025736 PucR C-terminal helix-turn-helix domain CAK77_RS21060 737eb4b4d472102c085bed0595441daf 505 Pfam PF07905 Purine catabolism regulatory protein-like family 4 121 1.3E-30 T 06-07-2017 IPR012914 Purine catabolism PurC-like domain CAK77_RS10525 c0ad9a0ef15f9015f9ee7197b1538647 602 Hamap MF_02112 Proteasome-associated ATPase [mpa]. 50 581 50.367 T 06-07-2017 IPR022482 Proteasome ATPase GO:0000502|GO:0010498|GO:0016887|GO:0019941 CAK77_RS10525 c0ad9a0ef15f9015f9ee7197b1538647 602 SMART SM00382 278 434 6.9E-22 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS10525 c0ad9a0ef15f9015f9ee7197b1538647 602 Pfam PF16450 Proteasomal ATPase OB/ID domain 92 239 7.6E-55 T 06-07-2017 IPR032501 Proteasomal ATPase, OB/ID domain CAK77_RS10525 c0ad9a0ef15f9015f9ee7197b1538647 602 SUPERFAMILY SSF52540 240 449 1.64E-49 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS10525 c0ad9a0ef15f9015f9ee7197b1538647 602 SUPERFAMILY SSF52540 490 532 1.64E-49 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS10525 c0ad9a0ef15f9015f9ee7197b1538647 602 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 282 432 1.6E-47 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 CAK77_RS10525 c0ad9a0ef15f9015f9ee7197b1538647 602 ProSitePatterns PS00674 AAA-protein family signature. 402 420 - T 06-07-2017 IPR003960 ATPase, AAA-type, conserved site GO:0005524 CAK77_RS10525 c0ad9a0ef15f9015f9ee7197b1538647 602 Gene3D G3DSA:3.40.50.300 231 452 7.1E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS10525 c0ad9a0ef15f9015f9ee7197b1538647 602 TIGRFAM TIGR03689 pup_AAA: proteasome ATPase 48 580 4.2E-262 T 06-07-2017 IPR022482 Proteasome ATPase GO:0000502|GO:0010498|GO:0016887|GO:0019941 CAK77_RS24145 db3cc6443160db86a1f30ab39d167d4f 462 PIRSF PIRSF006060 1 459 8.3E-75 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CAK77_RS24145 db3cc6443160db86a1f30ab39d167d4f 462 Pfam PF00324 Amino acid permease 20 447 1.8E-110 T 06-07-2017 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CAK77_RS24145 db3cc6443160db86a1f30ab39d167d4f 462 ProSitePatterns PS00218 Amino acid permeases signature. 45 75 - T 06-07-2017 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 CAK77_RS02850 837a2064856041e0b275a84f0a953a82 261 Gene3D G3DSA:3.40.50.300 3 226 2.7E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS02850 837a2064856041e0b275a84f0a953a82 261 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK77_RS02850 837a2064856041e0b275a84f0a953a82 261 Pfam PF00005 ABC transporter 19 167 2.2E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK77_RS02850 837a2064856041e0b275a84f0a953a82 261 SMART SM00382 27 212 4.8E-16 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS02850 837a2064856041e0b275a84f0a953a82 261 SUPERFAMILY SSF52540 3 228 4.07E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS06065 2bab53010ccc274a2f5497c59d2aa283 243 Pfam PF03006 Haemolysin-III related 34 234 8.4E-44 T 06-07-2017 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 CAK77_RS06065 2bab53010ccc274a2f5497c59d2aa283 243 TIGRFAM TIGR01065 hlyIII: channel protein, hemolysin III family 35 240 7.0E-59 T 06-07-2017 IPR005744 Hly-III GO:0016021|GO:0019835 CAK77_RS07205 bb6489dd98ffee5f055f80ce7016cc67 306 Pfam PF00288 GHMP kinases N terminal domain 89 152 1.1E-9 T 06-07-2017 IPR006204 GHMP kinase N-terminal domain GO:0005524 CAK77_RS07205 bb6489dd98ffee5f055f80ce7016cc67 306 PIRSF PIRSF000676 7 302 3.2E-78 T 06-07-2017 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 CAK77_RS07205 bb6489dd98ffee5f055f80ce7016cc67 306 Gene3D G3DSA:3.30.70.890 174 285 4.2E-32 T 06-07-2017 IPR013750 GHMP kinase, C-terminal domain CAK77_RS07205 bb6489dd98ffee5f055f80ce7016cc67 306 SUPERFAMILY SSF55060 177 302 8.63E-24 T 06-07-2017 IPR013750 GHMP kinase, C-terminal domain CAK77_RS07205 bb6489dd98ffee5f055f80ce7016cc67 306 PRINTS PR00958 Homoserine kinase signature 101 116 5.6E-36 T 06-07-2017 CAK77_RS07205 bb6489dd98ffee5f055f80ce7016cc67 306 PRINTS PR00958 Homoserine kinase signature 259 274 5.6E-36 T 06-07-2017 CAK77_RS07205 bb6489dd98ffee5f055f80ce7016cc67 306 PRINTS PR00958 Homoserine kinase signature 139 152 5.6E-36 T 06-07-2017 CAK77_RS07205 bb6489dd98ffee5f055f80ce7016cc67 306 PRINTS PR00958 Homoserine kinase signature 182 199 5.6E-36 T 06-07-2017 CAK77_RS07205 bb6489dd98ffee5f055f80ce7016cc67 306 PRINTS PR00958 Homoserine kinase signature 18 33 5.6E-36 T 06-07-2017 CAK77_RS07205 bb6489dd98ffee5f055f80ce7016cc67 306 Gene3D G3DSA:3.30.230.10 11 160 4.2E-50 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CAK77_RS07205 bb6489dd98ffee5f055f80ce7016cc67 306 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 94 105 - T 06-07-2017 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 CAK77_RS07205 bb6489dd98ffee5f055f80ce7016cc67 306 SUPERFAMILY SSF54211 12 157 3.64E-27 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAK77_RS07205 bb6489dd98ffee5f055f80ce7016cc67 306 TIGRFAM TIGR00191 thrB: homoserine kinase 12 277 2.6E-61 T 06-07-2017 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 CAK77_RS07205 bb6489dd98ffee5f055f80ce7016cc67 306 Hamap MF_00384 Homoserine kinase [thrB]. 11 306 27.952 T 06-07-2017 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 CAK77_RS16010 003fb9c94e17e42647c9b474c6811012 101 Pfam PF04226 Transglycosylase associated protein 50 99 1.9E-14 T 06-07-2017 IPR007341 Transglycosylase-associated protein GO:0016021 CAK77_RS17950 68bd9c2af1501a82a3023fcac38ac774 458 SUPERFAMILY SSF55469 260 445 8.25E-33 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CAK77_RS17950 68bd9c2af1501a82a3023fcac38ac774 458 TIGRFAM TIGR03553 F420_FbiB_CTERM: F420 biosynthesis protein FbiB, C-terminal domain 261 457 2.3E-91 T 06-07-2017 IPR019943 Coenzyme F420 biosynthesis protein FbiB, C-terminal GO:0016881 KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 CAK77_RS17950 68bd9c2af1501a82a3023fcac38ac774 458 Gene3D G3DSA:3.30.1330.100 128 227 5.5E-53 T 06-07-2017 CAK77_RS17950 68bd9c2af1501a82a3023fcac38ac774 458 Gene3D G3DSA:3.30.1330.100 18 65 5.5E-53 T 06-07-2017 CAK77_RS17950 68bd9c2af1501a82a3023fcac38ac774 458 TIGRFAM TIGR01916 F420_cofE: coenzyme F420-0:L-glutamate ligase 18 248 4.8E-79 T 06-07-2017 IPR008225 Coenzyme F420:L-glutamate ligase GO:0043773|GO:0046872|GO:0051188 KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 CAK77_RS17950 68bd9c2af1501a82a3023fcac38ac774 458 Gene3D G3DSA:3.40.109.10 261 448 4.8E-35 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CAK77_RS17950 68bd9c2af1501a82a3023fcac38ac774 458 SUPERFAMILY SSF144010 20 253 1.05E-65 T 06-07-2017 CAK77_RS17950 68bd9c2af1501a82a3023fcac38ac774 458 Pfam PF01996 F420-0:Gamma-glutamyl ligase 26 225 1.4E-39 T 06-07-2017 IPR002847 Coenzyme F420:L-glutamate ligase-like domain KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 CAK77_RS17950 68bd9c2af1501a82a3023fcac38ac774 458 Pfam PF00881 Nitroreductase family 263 434 8.0E-27 T 06-07-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 CAK77_RS17950 68bd9c2af1501a82a3023fcac38ac774 458 Hamap MF_01259 Coenzyme F420:L-glutamate ligase [fbiB]. 23 458 51.506 T 06-07-2017 IPR023661 Coenzyme F420:L-glutamate ligase, bacteria GO:0043773|GO:0046872|GO:0051188 KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 CAK77_RS08210 3a2c6f5b1b0bb54673024efb2e31f91e 949 Gene3D G3DSA:2.40.50.140 402 492 5.0E-29 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS08210 3a2c6f5b1b0bb54673024efb2e31f91e 949 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 384 792 6.4E-153 T 06-07-2017 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 CAK77_RS08210 3a2c6f5b1b0bb54673024efb2e31f91e 949 Pfam PF10150 Ribonuclease E/G family 488 763 8.4E-102 T 06-07-2017 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 CAK77_RS08210 3a2c6f5b1b0bb54673024efb2e31f91e 949 SUPERFAMILY SSF50249 409 492 1.83E-16 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS08210 3a2c6f5b1b0bb54673024efb2e31f91e 949 SMART SM00316 407 486 6.3E-9 T 06-07-2017 IPR022967 RNA-binding domain, S1 CAK77_RS01835 b4da78b0f301049eba6d7353e1f5c8f6 300 Gene3D G3DSA:3.30.420.40 202 272 1.5E-4 T 06-07-2017 CAK77_RS01835 b4da78b0f301049eba6d7353e1f5c8f6 300 SUPERFAMILY SSF53067 6 106 6.66E-9 T 06-07-2017 CAK77_RS01835 b4da78b0f301049eba6d7353e1f5c8f6 300 SUPERFAMILY SSF53067 111 290 5.34E-40 T 06-07-2017 CAK77_RS01835 b4da78b0f301049eba6d7353e1f5c8f6 300 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 7 290 1.5E-22 T 06-07-2017 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 CAK77_RS10315 edfc0c090785f0453761cdb1814f8603 1675 Gene3D G3DSA:3.40.50.980 636 794 3.2E-42 T 06-07-2017 CAK77_RS10315 edfc0c090785f0453761cdb1814f8603 1675 SUPERFAMILY SSF52777 218 463 2.11E-45 T 06-07-2017 CAK77_RS10315 edfc0c090785f0453761cdb1814f8603 1675 SUPERFAMILY SSF56801 456 1002 1.07E-148 T 06-07-2017 CAK77_RS10315 edfc0c090785f0453761cdb1814f8603 1675 SMART SM01294 1567 1630 3.8E-4 T 06-07-2017 CAK77_RS10315 edfc0c090785f0453761cdb1814f8603 1675 SUPERFAMILY SSF52777 44 216 9.89E-38 T 06-07-2017 CAK77_RS10315 edfc0c090785f0453761cdb1814f8603 1675 SUPERFAMILY SSF52777 1281 1530 1.82E-50 T 06-07-2017 CAK77_RS10315 edfc0c090785f0453761cdb1814f8603 1675 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1590 1605 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site CAK77_RS10315 edfc0c090785f0453761cdb1814f8603 1675 Pfam PF13193 AMP-binding enzyme C-terminal domain 890 966 1.3E-12 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAK77_RS10315 edfc0c090785f0453761cdb1814f8603 1675 SUPERFAMILY SSF52777 1094 1293 5.34E-43 T 06-07-2017 CAK77_RS10315 edfc0c090785f0453761cdb1814f8603 1675 Gene3D G3DSA:2.30.38.10 795 872 4.9E-26 T 06-07-2017 CAK77_RS10315 edfc0c090785f0453761cdb1814f8603 1675 SMART SM00823 Phosphopantetheine attachment site 1566 1634 5.0E-4 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAK77_RS10315 edfc0c090785f0453761cdb1814f8603 1675 SMART SM00823 Phosphopantetheine attachment site 991 1060 1.0E-8 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAK77_RS10315 edfc0c090785f0453761cdb1814f8603 1675 ProSitePatterns PS00455 Putative AMP-binding domain signature. 627 638 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK77_RS10315 edfc0c090785f0453761cdb1814f8603 1675 Gene3D G3DSA:3.30.300.30 877 994 8.5E-33 T 06-07-2017 CAK77_RS10315 edfc0c090785f0453761cdb1814f8603 1675 Pfam PF00668 Condensation domain 43 327 1.1E-52 T 06-07-2017 IPR001242 Condensation domain CAK77_RS10315 edfc0c090785f0453761cdb1814f8603 1675 Pfam PF00668 Condensation domain 1099 1391 1.0E-53 T 06-07-2017 IPR001242 Condensation domain CAK77_RS10315 edfc0c090785f0453761cdb1814f8603 1675 Pfam PF00501 AMP-binding enzyme 495 882 5.1E-94 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK77_RS10315 edfc0c090785f0453761cdb1814f8603 1675 SUPERFAMILY SSF47336 985 1056 4.32E-19 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS10315 edfc0c090785f0453761cdb1814f8603 1675 SUPERFAMILY SSF47336 1562 1630 1.14E-12 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS10315 edfc0c090785f0453761cdb1814f8603 1675 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 515 905 9.5E-126 T 06-07-2017 IPR010071 Amino acid adenylation domain CAK77_RS10315 edfc0c090785f0453761cdb1814f8603 1675 Gene3D G3DSA:3.40.50.980 488 635 6.1E-46 T 06-07-2017 CAK77_RS10315 edfc0c090785f0453761cdb1814f8603 1675 Pfam PF00550 Phosphopantetheine attachment site 1002 1055 3.7E-13 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS10315 edfc0c090785f0453761cdb1814f8603 1675 Pfam PF00550 Phosphopantetheine attachment site 1569 1630 2.3E-10 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS10315 edfc0c090785f0453761cdb1814f8603 1675 Pfam PF13745 HxxPF-repeated domain 1414 1508 4.8E-20 T 06-07-2017 CAK77_RS10315 edfc0c090785f0453761cdb1814f8603 1675 Pfam PF13745 HxxPF-repeated domain 350 433 3.9E-10 T 06-07-2017 CAK77_RS10315 edfc0c090785f0453761cdb1814f8603 1675 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1015 1030 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site CAK77_RS10315 edfc0c090785f0453761cdb1814f8603 1675 Gene3D G3DSA:1.10.1200.10 995 1056 1.3E-25 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS10315 edfc0c090785f0453761cdb1814f8603 1675 Gene3D G3DSA:1.10.1200.10 1557 1633 1.1E-16 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS17640 30e0069c9eb7c8e35d24e9eac23876f2 837 Gene3D G3DSA:3.90.480.10 558 618 1.7E-9 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAK77_RS17640 30e0069c9eb7c8e35d24e9eac23876f2 837 Gene3D G3DSA:3.30.413.10 621 758 5.0E-32 T 06-07-2017 CAK77_RS17640 30e0069c9eb7c8e35d24e9eac23876f2 837 SUPERFAMILY SSF51905 150 308 2.33E-23 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS17640 30e0069c9eb7c8e35d24e9eac23876f2 837 PRINTS PR00397 Sirohaem Fe-binding site signature 668 686 3.3E-6 T 06-07-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAK77_RS17640 30e0069c9eb7c8e35d24e9eac23876f2 837 PRINTS PR00397 Sirohaem Fe-binding site signature 625 643 3.3E-6 T 06-07-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAK77_RS17640 30e0069c9eb7c8e35d24e9eac23876f2 837 PIRSF PIRSF037149 1 823 0.0 T 06-07-2017 IPR017121 Nitrite reductase [NAD(P)H], large subunit GO:0042128 CAK77_RS17640 30e0069c9eb7c8e35d24e9eac23876f2 837 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 549 610 2.4E-10 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAK77_RS17640 30e0069c9eb7c8e35d24e9eac23876f2 837 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 283 2.3E-46 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS17640 30e0069c9eb7c8e35d24e9eac23876f2 837 SUPERFAMILY SSF51905 2 189 2.59E-38 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS17640 30e0069c9eb7c8e35d24e9eac23876f2 837 SUPERFAMILY SSF56014 622 796 1.83E-47 T 06-07-2017 CAK77_RS17640 30e0069c9eb7c8e35d24e9eac23876f2 837 SUPERFAMILY SSF55124 491 630 8.34E-26 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAK77_RS17640 30e0069c9eb7c8e35d24e9eac23876f2 837 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 5.3E-13 T 06-07-2017 CAK77_RS17640 30e0069c9eb7c8e35d24e9eac23876f2 837 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 261 283 5.3E-13 T 06-07-2017 CAK77_RS17640 30e0069c9eb7c8e35d24e9eac23876f2 837 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 101 119 5.3E-13 T 06-07-2017 CAK77_RS17640 30e0069c9eb7c8e35d24e9eac23876f2 837 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 148 166 5.3E-13 T 06-07-2017 CAK77_RS17640 30e0069c9eb7c8e35d24e9eac23876f2 837 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 668 684 - T 06-07-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAK77_RS17640 30e0069c9eb7c8e35d24e9eac23876f2 837 Gene3D G3DSA:3.50.50.60 105 309 1.6E-41 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS17640 30e0069c9eb7c8e35d24e9eac23876f2 837 TIGRFAM TIGR02374 nitri_red_nirB: nitrite reductase [NAD(P)H], large subunit 5 790 0.0 T 06-07-2017 IPR012744 Nitrite reductase [NAD(P)H] large subunit, NirB GO:0008942|GO:0042128|GO:0050660|GO:0050661|GO:0055114 CAK77_RS17640 30e0069c9eb7c8e35d24e9eac23876f2 837 Pfam PF04324 BFD-like [2Fe-2S] binding domain 417 464 3.3E-11 T 06-07-2017 IPR007419 BFD-like [2Fe-2S]-binding domain CAK77_RS17640 30e0069c9eb7c8e35d24e9eac23876f2 837 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 621 759 2.7E-16 T 06-07-2017 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAK77_RS17640 30e0069c9eb7c8e35d24e9eac23876f2 837 Gene3D G3DSA:3.50.50.60 1 104 3.5E-24 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS17630 3c0e083cf5bbbf993491dc1a47454748 384 Pfam PF00486 Transcriptional regulatory protein, C terminal 306 372 4.8E-14 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAK77_RS17630 3c0e083cf5bbbf993491dc1a47454748 384 SUPERFAMILY SSF46894 284 372 5.95E-14 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAK77_RS17630 3c0e083cf5bbbf993491dc1a47454748 384 Pfam PF02602 Uroporphyrinogen-III synthase HemD 25 270 7.1E-37 T 06-07-2017 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAK77_RS17630 3c0e083cf5bbbf993491dc1a47454748 384 SUPERFAMILY SSF69618 12 278 8.11E-52 T 06-07-2017 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAK77_RS17630 3c0e083cf5bbbf993491dc1a47454748 384 Gene3D G3DSA:3.40.50.10090 139 280 6.8E-32 T 06-07-2017 CAK77_RS17630 3c0e083cf5bbbf993491dc1a47454748 384 Gene3D G3DSA:3.40.50.10090 8 138 5.3E-30 T 06-07-2017 CAK77_RS17630 3c0e083cf5bbbf993491dc1a47454748 384 SMART SM00862 302 372 8.8E-16 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAK77_RS17630 3c0e083cf5bbbf993491dc1a47454748 384 Gene3D G3DSA:1.10.10.10 282 373 1.1E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS05600 c7d27eebeca3671356990b96b384b62c 375 SMART SM01208 207 285 1.7E-17 T 06-07-2017 IPR011098 G5 domain CAK77_RS05600 c7d27eebeca3671356990b96b384b62c 375 Gene3D G3DSA:1.10.530.10 270 373 2.3E-41 T 06-07-2017 CAK77_RS05600 c7d27eebeca3671356990b96b384b62c 375 Pfam PF06737 Transglycosylase-like domain 295 368 2.2E-33 T 06-07-2017 IPR010618 Transglycosylase-like CAK77_RS05600 c7d27eebeca3671356990b96b384b62c 375 Pfam PF07501 G5 domain 211 284 8.7E-14 T 06-07-2017 IPR011098 G5 domain CAK77_RS05600 c7d27eebeca3671356990b96b384b62c 375 SUPERFAMILY SSF53955 292 374 6.19E-32 T 06-07-2017 IPR023346 Lysozyme-like domain CAK77_RS05600 c7d27eebeca3671356990b96b384b62c 375 Pfam PF03990 Domain of unknown function (DUF348) 154 194 8.1E-6 T 06-07-2017 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 CAK77_RS05600 c7d27eebeca3671356990b96b384b62c 375 Pfam PF03990 Domain of unknown function (DUF348) 40 78 2.9E-8 T 06-07-2017 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 CAK77_RS05600 c7d27eebeca3671356990b96b384b62c 375 Pfam PF03990 Domain of unknown function (DUF348) 98 127 1.2E-8 T 06-07-2017 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 CAK77_RS15570 ec68cf90aba76c3c0daa172d50e5a95b 98 Gene3D G3DSA:3.30.1230.10 6 89 3.5E-25 T 06-07-2017 IPR007393 Domain of unknown function DUF448 CAK77_RS15570 ec68cf90aba76c3c0daa172d50e5a95b 98 Pfam PF04296 Protein of unknown function (DUF448) 12 88 4.3E-22 T 06-07-2017 IPR007393 Domain of unknown function DUF448 CAK77_RS15570 ec68cf90aba76c3c0daa172d50e5a95b 98 SUPERFAMILY SSF64376 9 90 3.27E-23 T 06-07-2017 IPR007393 Domain of unknown function DUF448 CAK77_RS22270 6d18c7620c324489e3ad89866f8f2d3e 1410 Gene3D G3DSA:2.60.120.260 952 1031 5.2E-4 T 06-07-2017 IPR008979 Galactose-binding domain-like CAK77_RS22270 6d18c7620c324489e3ad89866f8f2d3e 1410 SUPERFAMILY SSF49785 708 831 9.92E-13 T 06-07-2017 IPR008979 Galactose-binding domain-like CAK77_RS22270 6d18c7620c324489e3ad89866f8f2d3e 1410 Gene3D G3DSA:2.60.120.260 709 842 4.3E-9 T 06-07-2017 IPR008979 Galactose-binding domain-like CAK77_RS22270 6d18c7620c324489e3ad89866f8f2d3e 1410 Pfam PF11847 Domain of unknown function (DUF3367) 22 692 6.0E-294 T 06-07-2017 IPR021798 Protein of unknown function DUF3367 MetaCyc: PWY-6397 CAK77_RS14595 77d6039f602a88c60183c6b960ff1145 270 SUPERFAMILY SSF56176 10 169 1.42E-23 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAK77_RS14595 77d6039f602a88c60183c6b960ff1145 270 Gene3D G3DSA:3.30.465.10 58 169 4.3E-19 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAK77_RS14595 77d6039f602a88c60183c6b960ff1145 270 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 27 168 1.1E-16 T 06-07-2017 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 CAK77_RS21580 1a851be3c6094e8c8ffadc048c6d82fc 127 Pfam PF07681 DoxX 6 83 6.1E-13 T 06-07-2017 IPR032808 DoxX family CAK77_RS09195 4b0ca0145f93f4243972a562f225c1a2 162 Gene3D G3DSA:3.40.50.270 3 155 4.9E-46 T 06-07-2017 CAK77_RS09195 4b0ca0145f93f4243972a562f225c1a2 162 SMART SM00226 4 151 1.5E-49 T 06-07-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily CAK77_RS09195 4b0ca0145f93f4243972a562f225c1a2 162 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 6 145 1.4E-38 T 06-07-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily CAK77_RS09195 4b0ca0145f93f4243972a562f225c1a2 162 SUPERFAMILY SSF52788 4 151 3.53E-43 T 06-07-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily CAK77_RS09195 4b0ca0145f93f4243972a562f225c1a2 162 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 49 65 4.9E-20 T 06-07-2017 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CAK77_RS09195 4b0ca0145f93f4243972a562f225c1a2 162 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 81 96 4.9E-20 T 06-07-2017 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CAK77_RS09195 4b0ca0145f93f4243972a562f225c1a2 162 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 6 23 4.9E-20 T 06-07-2017 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CAK77_RS09195 4b0ca0145f93f4243972a562f225c1a2 162 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 123 138 4.9E-20 T 06-07-2017 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CAK77_RS18330 0b165b1d52e4d5e821bb429f4cc726e1 342 Gene3D G3DSA:2.120.10.30 20 328 3.0E-52 T 06-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like CAK77_RS18330 0b165b1d52e4d5e821bb429f4cc726e1 342 SUPERFAMILY SSF63829 280 329 6.38E-47 T 06-07-2017 CAK77_RS18330 0b165b1d52e4d5e821bb429f4cc726e1 342 SUPERFAMILY SSF63829 5 246 6.38E-47 T 06-07-2017 CAK77_RS18330 0b165b1d52e4d5e821bb429f4cc726e1 342 Pfam PF03088 Strictosidine synthase 133 212 5.7E-19 T 06-07-2017 IPR018119 Strictosidine synthase, conserved region GO:0009058|GO:0016844 CAK77_RS06955 4fc46c318845ea528a9f7ec4fd716c3e 276 Gene3D G3DSA:3.40.50.720 5 239 9.6E-62 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS06955 4fc46c318845ea528a9f7ec4fd716c3e 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 5.8E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06955 4fc46c318845ea528a9f7ec4fd716c3e 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 5.8E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06955 4fc46c318845ea528a9f7ec4fd716c3e 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 5.8E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06955 4fc46c318845ea528a9f7ec4fd716c3e 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 5.8E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06955 4fc46c318845ea528a9f7ec4fd716c3e 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 5.8E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06955 4fc46c318845ea528a9f7ec4fd716c3e 276 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK77_RS06955 4fc46c318845ea528a9f7ec4fd716c3e 276 Pfam PF00106 short chain dehydrogenase 7 199 1.3E-48 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06955 4fc46c318845ea528a9f7ec4fd716c3e 276 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 2.0E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06955 4fc46c318845ea528a9f7ec4fd716c3e 276 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 2.0E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06955 4fc46c318845ea528a9f7ec4fd716c3e 276 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 2.0E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06955 4fc46c318845ea528a9f7ec4fd716c3e 276 SUPERFAMILY SSF51735 3 264 2.01E-62 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS22940 7b6052193da3815496fad94d601c12c7 393 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 137 226 3.8E-20 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAK77_RS22940 7b6052193da3815496fad94d601c12c7 393 Gene3D G3DSA:1.10.540.10 9 133 5.6E-35 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS22940 7b6052193da3815496fad94d601c12c7 393 Gene3D G3DSA:2.40.110.10 136 235 3.7E-34 T 06-07-2017 CAK77_RS22940 7b6052193da3815496fad94d601c12c7 393 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 21 133 5.9E-27 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS22940 7b6052193da3815496fad94d601c12c7 393 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 240 386 7.7E-31 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS22940 7b6052193da3815496fad94d601c12c7 393 SUPERFAMILY SSF56645 11 236 1.83E-68 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK77_RS22940 7b6052193da3815496fad94d601c12c7 393 SUPERFAMILY SSF47203 243 389 2.9E-37 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS22940 7b6052193da3815496fad94d601c12c7 393 Gene3D G3DSA:1.20.140.10 240 389 4.6E-40 T 06-07-2017 CAK77_RS21920 d5a5720bfbe61f0bafec612a642ad710 211 SMART SM00796 7 198 3.9E-84 T 06-07-2017 IPR003833 Carboxyltransferase domain, subdomain C and D CAK77_RS21920 d5a5720bfbe61f0bafec612a642ad710 211 SUPERFAMILY SSF160467 9 91 5.49E-7 T 06-07-2017 CAK77_RS21920 d5a5720bfbe61f0bafec612a642ad710 211 Gene3D G3DSA:3.30.1360.40 8 55 1.1E-4 T 06-07-2017 IPR024946 Arginine repressor C-terminal-like domain CAK77_RS21920 d5a5720bfbe61f0bafec612a642ad710 211 SUPERFAMILY SSF50891 87 210 2.73E-42 T 06-07-2017 IPR029000 Cyclophilin-like domain CAK77_RS21920 d5a5720bfbe61f0bafec612a642ad710 211 Pfam PF02682 Allophanate hydrolase subunit 1 8 198 1.8E-64 T 06-07-2017 IPR003833 Carboxyltransferase domain, subdomain C and D CAK77_RS21920 d5a5720bfbe61f0bafec612a642ad710 211 Gene3D G3DSA:2.40.100.10 87 210 1.8E-49 T 06-07-2017 IPR029000 Cyclophilin-like domain CAK77_RS01355 1963f7095709287243ebccb7721b9ed2 250 SUPERFAMILY SSF161098 21 205 1.96E-31 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS01355 1963f7095709287243ebccb7721b9ed2 250 Gene3D G3DSA:1.10.3720.10 23 206 4.3E-23 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS01355 1963f7095709287243ebccb7721b9ed2 250 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 46 205 3.0E-19 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS03880 edd2e473596cf228000081ba910c10f6 479 SUPERFAMILY SSF53041 16 164 1.7E-25 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CAK77_RS03880 edd2e473596cf228000081ba910c10f6 479 Pfam PF07508 Recombinase 183 269 4.2E-11 T 06-07-2017 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 CAK77_RS03880 edd2e473596cf228000081ba910c10f6 479 Gene3D G3DSA:3.40.50.1390 16 145 2.6E-21 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CAK77_RS03880 edd2e473596cf228000081ba910c10f6 479 SMART SM00857 16 165 5.1E-40 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CAK77_RS03880 edd2e473596cf228000081ba910c10f6 479 Pfam PF13408 Recombinase zinc beta ribbon domain 283 342 3.5E-9 T 06-07-2017 IPR025827 Recombinase zinc beta ribbon domain CAK77_RS03880 edd2e473596cf228000081ba910c10f6 479 Pfam PF00239 Resolvase, N terminal domain 16 163 5.4E-27 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CAK77_RS04320 355ee782578433e82a5ac22293c766ce 463 Pfam PF00668 Condensation domain 73 334 2.6E-10 T 06-07-2017 IPR001242 Condensation domain CAK77_RS04320 355ee782578433e82a5ac22293c766ce 463 SUPERFAMILY SSF52777 226 458 4.0E-17 T 06-07-2017 CAK77_RS04320 355ee782578433e82a5ac22293c766ce 463 SUPERFAMILY SSF52777 68 211 2.67E-16 T 06-07-2017 CAK77_RS18020 c8d3e34237a5f1e0a97b72412c72dc5e 339 Pfam PF12833 Helix-turn-helix domain 253 329 6.9E-16 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK77_RS18020 c8d3e34237a5f1e0a97b72412c72dc5e 339 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 22 203 3.9E-44 T 06-07-2017 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal CAK77_RS18020 c8d3e34237a5f1e0a97b72412c72dc5e 339 SMART SM00342 246 328 1.5E-16 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK77_RS18020 c8d3e34237a5f1e0a97b72412c72dc5e 339 Gene3D G3DSA:1.10.10.60 281 329 2.4E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS18020 c8d3e34237a5f1e0a97b72412c72dc5e 339 SUPERFAMILY SSF46689 281 329 1.03E-8 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS18020 c8d3e34237a5f1e0a97b72412c72dc5e 339 Gene3D G3DSA:1.10.10.10 230 268 4.4E-4 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS14650 3e7b75e0c550b5198834396300570911 188 Pfam PF12804 MobA-like NTP transferase domain 12 167 8.6E-18 T 06-07-2017 IPR025877 MobA-like NTP transferase CAK77_RS14650 3e7b75e0c550b5198834396300570911 188 Gene3D G3DSA:3.90.550.10 11 176 2.0E-10 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK77_RS14650 3e7b75e0c550b5198834396300570911 188 SUPERFAMILY SSF53448 11 169 2.22E-12 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK77_RS22950 6c040b737f9a0a1b1054d89ff670849b 235 ProSitePatterns PS01081 TetR-type HTH domain signature. 22 52 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CAK77_RS22950 6c040b737f9a0a1b1054d89ff670849b 235 Gene3D G3DSA:1.10.357.10 3 84 3.0E-23 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS22950 6c040b737f9a0a1b1054d89ff670849b 235 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 31 54 2.1E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS22950 6c040b737f9a0a1b1054d89ff670849b 235 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 10 23 2.1E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS22950 6c040b737f9a0a1b1054d89ff670849b 235 SUPERFAMILY SSF46689 6 72 1.05E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS22950 6c040b737f9a0a1b1054d89ff670849b 235 Pfam PF00440 Bacterial regulatory proteins, tetR family 10 56 7.9E-18 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS19165 f6dacb6f762370b51f9f67485bb0ad69 285 Pfam PF02274 Amidinotransferase 55 284 1.1E-16 T 06-07-2017 CAK77_RS19165 f6dacb6f762370b51f9f67485bb0ad69 285 Gene3D G3DSA:3.75.10.10 24 283 5.4E-66 T 06-07-2017 CAK77_RS19165 f6dacb6f762370b51f9f67485bb0ad69 285 SUPERFAMILY SSF55909 19 283 1.78E-59 T 06-07-2017 CAK77_RS10480 0202fe3be5aa16c8c48606ac597aefaf 216 SUPERFAMILY SSF50800 3 214 1.2E-52 T 06-07-2017 IPR011037 Pyruvate kinase-like, insert domain CAK77_RS10480 0202fe3be5aa16c8c48606ac597aefaf 216 Pfam PF03473 MOSC domain 54 167 2.4E-23 T 06-07-2017 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 CAK77_RS10480 0202fe3be5aa16c8c48606ac597aefaf 216 Gene3D G3DSA:2.40.33.20 2 214 4.0E-69 T 06-07-2017 IPR015808 Molybdenum cofactor sulfurase, C-terminal-like CAK77_RS18700 790d781c10e836d7d6609bd66c170640 504 Pfam PF09423 PhoD-like phosphatase 143 486 6.2E-76 T 06-07-2017 IPR018946 Alkaline phosphatase D-related CAK77_RS18700 790d781c10e836d7d6609bd66c170640 504 Gene3D G3DSA:3.60.21.10 132 503 3.1E-23 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAK77_RS18700 790d781c10e836d7d6609bd66c170640 504 Pfam PF16655 PhoD-like phosphatase, N-terminal domain 38 126 2.2E-17 T 06-07-2017 IPR032093 Phospholipase D, N-terminal CAK77_RS18700 790d781c10e836d7d6609bd66c170640 504 SUPERFAMILY SSF56300 132 501 1.8E-30 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAK77_RS22040 792d06707ff16fef80f2c2b0b306e2fd 350 SMART SM01329 6 345 6.9E-160 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CAK77_RS22040 792d06707ff16fef80f2c2b0b306e2fd 350 Gene3D G3DSA:3.40.718.10 5 339 5.5E-114 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CAK77_RS22040 792d06707ff16fef80f2c2b0b306e2fd 350 SUPERFAMILY SSF53659 3 347 1.34E-112 T 06-07-2017 CAK77_RS22040 792d06707ff16fef80f2c2b0b306e2fd 350 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 7 344 1.6E-85 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CAK77_RS22040 792d06707ff16fef80f2c2b0b306e2fd 350 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 238 257 - T 06-07-2017 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 CAK77_RS19430 bec6635b8ced2dae69e94d6cc4a4d1e1 235 Pfam PF00687 Ribosomal protein L1p/L10e family 31 220 5.5E-51 T 06-07-2017 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein CAK77_RS19430 bec6635b8ced2dae69e94d6cc4a4d1e1 235 Gene3D G3DSA:3.30.190.20 161 226 2.9E-45 T 06-07-2017 IPR016094 Ribosomal protein L1, 2-layer alpha/beta-sandwich GO:0003723 CAK77_RS19430 bec6635b8ced2dae69e94d6cc4a4d1e1 235 Gene3D G3DSA:3.30.190.20 16 68 2.9E-45 T 06-07-2017 IPR016094 Ribosomal protein L1, 2-layer alpha/beta-sandwich GO:0003723 CAK77_RS19430 bec6635b8ced2dae69e94d6cc4a4d1e1 235 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 225 2.9E-102 T 06-07-2017 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 CAK77_RS19430 bec6635b8ced2dae69e94d6cc4a4d1e1 235 PIRSF PIRSF002155 1 226 8.5E-75 T 06-07-2017 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK77_RS19430 bec6635b8ced2dae69e94d6cc4a4d1e1 235 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 139 - T 06-07-2017 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK77_RS19430 bec6635b8ced2dae69e94d6cc4a4d1e1 235 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 229 42.475 T 06-07-2017 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 CAK77_RS19430 bec6635b8ced2dae69e94d6cc4a4d1e1 235 SUPERFAMILY SSF56808 6 226 6.15E-81 T 06-07-2017 IPR023674 Ribosomal protein L1-like CAK77_RS19430 bec6635b8ced2dae69e94d6cc4a4d1e1 235 Gene3D G3DSA:3.40.50.790 69 159 2.8E-41 T 06-07-2017 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich CAK77_RS00695 4dd803e54220a09db3e7c9352c121a1c 395 Gene3D G3DSA:3.20.20.10 24 141 9.2E-7 T 06-07-2017 IPR029066 PLP-binding barrel CAK77_RS00695 4dd803e54220a09db3e7c9352c121a1c 395 SUPERFAMILY SSF51419 21 283 5.89E-20 T 06-07-2017 IPR029066 PLP-binding barrel CAK77_RS00695 4dd803e54220a09db3e7c9352c121a1c 395 Pfam PF01168 Alanine racemase, N-terminal domain 20 193 1.6E-12 T 06-07-2017 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAK77_RS21030 59d2f60700402e5fdc996e6401055821 546 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 82 505 2.3E-207 T 06-07-2017 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 CAK77_RS21030 59d2f60700402e5fdc996e6401055821 546 Pfam PF13667 ThiC-associated domain 19 79 3.4E-10 T 06-07-2017 IPR025747 ThiC-associated domain KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 CAK77_RS21030 59d2f60700402e5fdc996e6401055821 546 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 81 508 55.735 T 06-07-2017 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 CAK77_RS21030 59d2f60700402e5fdc996e6401055821 546 Pfam PF01964 Radical SAM ThiC family 82 502 1.7E-199 T 06-07-2017 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 CAK77_RS07685 309aecc496951dd4f3c296231659d129 285 Gene3D G3DSA:3.40.50.720 11 227 4.2E-63 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS07685 309aecc496951dd4f3c296231659d129 285 Pfam PF00106 short chain dehydrogenase 13 195 6.6E-49 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS07685 309aecc496951dd4f3c296231659d129 285 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK77_RS07685 309aecc496951dd4f3c296231659d129 285 SUPERFAMILY SSF51735 7 259 2.21E-65 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS07685 309aecc496951dd4f3c296231659d129 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 2.8E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS07685 309aecc496951dd4f3c296231659d129 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 2.8E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS07685 309aecc496951dd4f3c296231659d129 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 2.8E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS07685 309aecc496951dd4f3c296231659d129 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 2.8E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS07685 309aecc496951dd4f3c296231659d129 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 2.8E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS07685 309aecc496951dd4f3c296231659d129 285 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 2.2E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS07685 309aecc496951dd4f3c296231659d129 285 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 2.2E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS07685 309aecc496951dd4f3c296231659d129 285 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 2.2E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS16730 4ee402c335d531613ec9522673d33cb6 273 Pfam PF08241 Methyltransferase domain 66 157 6.0E-22 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CAK77_RS16730 4ee402c335d531613ec9522673d33cb6 273 Gene3D G3DSA:3.40.50.150 46 209 2.7E-39 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS16730 4ee402c335d531613ec9522673d33cb6 273 SUPERFAMILY SSF53335 44 212 1.01E-38 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS15565 122dc9bc448c2efd53233ba43c470417 912 SUPERFAMILY SSF52156 693 820 2.35E-35 T 06-07-2017 IPR023115 Translation initiation factor IF- 2, domain 3 CAK77_RS15565 122dc9bc448c2efd53233ba43c470417 912 SUPERFAMILY SSF50447 814 911 4.37E-26 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain CAK77_RS15565 122dc9bc448c2efd53233ba43c470417 912 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 410 571 3.0E-32 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 CAK77_RS15565 122dc9bc448c2efd53233ba43c470417 912 SUPERFAMILY SSF50447 586 669 6.86E-24 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain CAK77_RS15565 122dc9bc448c2efd53233ba43c470417 912 Pfam PF11987 Translation-initiation factor 2 704 803 2.9E-32 T 06-07-2017 IPR023115 Translation initiation factor IF- 2, domain 3 CAK77_RS15565 122dc9bc448c2efd53233ba43c470417 912 Gene3D G3DSA:2.40.30.10 815 911 7.6E-33 T 06-07-2017 CAK77_RS15565 122dc9bc448c2efd53233ba43c470417 912 Gene3D G3DSA:3.40.50.10050 712 792 3.8E-21 T 06-07-2017 IPR023115 Translation initiation factor IF- 2, domain 3 CAK77_RS15565 122dc9bc448c2efd53233ba43c470417 912 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 4 911 16.756 T 06-07-2017 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 CAK77_RS15565 122dc9bc448c2efd53233ba43c470417 912 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 320 911 1.1E-225 T 06-07-2017 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 CAK77_RS15565 122dc9bc448c2efd53233ba43c470417 912 Pfam PF00009 Elongation factor Tu GTP binding domain 413 573 7.4E-33 T 06-07-2017 CAK77_RS15565 122dc9bc448c2efd53233ba43c470417 912 Gene3D G3DSA:3.40.50.300 404 572 8.3E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS15565 122dc9bc448c2efd53233ba43c470417 912 SUPERFAMILY SSF52540 405 575 2.7E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS15565 122dc9bc448c2efd53233ba43c470417 912 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 4 52 2.6E-14 T 06-07-2017 IPR006847 Translation initiation factor IF-2, N-terminal CAK77_RS15565 122dc9bc448c2efd53233ba43c470417 912 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 328 373 3.8E-6 T 06-07-2017 IPR006847 Translation initiation factor IF-2, N-terminal CAK77_RS15565 122dc9bc448c2efd53233ba43c470417 912 Gene3D G3DSA:2.40.30.10 584 677 1.4E-21 T 06-07-2017 CAK77_RS15565 122dc9bc448c2efd53233ba43c470417 912 PRINTS PR00315 GTP-binding elongation factor signature 480 491 6.5E-10 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAK77_RS15565 122dc9bc448c2efd53233ba43c470417 912 PRINTS PR00315 GTP-binding elongation factor signature 464 474 6.5E-10 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAK77_RS15565 122dc9bc448c2efd53233ba43c470417 912 PRINTS PR00315 GTP-binding elongation factor signature 516 525 6.5E-10 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAK77_RS15565 122dc9bc448c2efd53233ba43c470417 912 PRINTS PR00315 GTP-binding elongation factor signature 412 425 6.5E-10 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAK77_RS19420 24e69c696d25057cf390837c18fd0051 567 Gene3D G3DSA:3.30.450.40 48 202 6.2E-31 T 06-07-2017 IPR029016 GAF domain-like CAK77_RS19420 24e69c696d25057cf390837c18fd0051 567 Gene3D G3DSA:3.30.450.40 205 366 2.5E-16 T 06-07-2017 IPR029016 GAF domain-like CAK77_RS19420 24e69c696d25057cf390837c18fd0051 567 SUPERFAMILY SSF55874 461 566 4.85E-13 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS19420 24e69c696d25057cf390837c18fd0051 567 Pfam PF13492 GAF domain 237 364 4.7E-8 T 06-07-2017 IPR003018 GAF domain GO:0005515 CAK77_RS19420 24e69c696d25057cf390837c18fd0051 567 Pfam PF13185 GAF domain 57 196 1.2E-16 T 06-07-2017 IPR003018 GAF domain GO:0005515 CAK77_RS19420 24e69c696d25057cf390837c18fd0051 567 Pfam PF07730 Histidine kinase 380 442 2.8E-9 T 06-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CAK77_RS19420 24e69c696d25057cf390837c18fd0051 567 SMART SM00065 58 205 5.0E-17 T 06-07-2017 IPR003018 GAF domain GO:0005515 CAK77_RS19420 24e69c696d25057cf390837c18fd0051 567 SMART SM00065 226 372 0.0022 T 06-07-2017 IPR003018 GAF domain GO:0005515 CAK77_RS19420 24e69c696d25057cf390837c18fd0051 567 SUPERFAMILY SSF55781 208 390 1.57E-19 T 06-07-2017 IPR029016 GAF domain-like CAK77_RS19420 24e69c696d25057cf390837c18fd0051 567 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 485 543 9.4E-7 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS19420 24e69c696d25057cf390837c18fd0051 567 SUPERFAMILY SSF55781 41 223 5.89E-38 T 06-07-2017 IPR029016 GAF domain-like CAK77_RS19420 24e69c696d25057cf390837c18fd0051 567 Gene3D G3DSA:3.30.565.10 435 531 9.3E-7 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS13900 32457e054b32da90934c8a0a8ddf3c5e 216 Hamap MF_00109 Shikimate kinase [aroK]. 2 167 26.396 T 06-07-2017 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 CAK77_RS13900 32457e054b32da90934c8a0a8ddf3c5e 216 SUPERFAMILY SSF52540 2 165 1.5E-27 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS13900 32457e054b32da90934c8a0a8ddf3c5e 216 Pfam PF01202 Shikimate kinase 11 166 4.1E-43 T 06-07-2017 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 CAK77_RS13900 32457e054b32da90934c8a0a8ddf3c5e 216 Gene3D G3DSA:3.40.50.300 4 168 9.4E-49 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS13900 32457e054b32da90934c8a0a8ddf3c5e 216 ProSitePatterns PS01128 Shikimate kinase signature. 58 83 - T 06-07-2017 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 CAK77_RS13900 32457e054b32da90934c8a0a8ddf3c5e 216 PRINTS PR01100 Shikimate kinase family signature 57 65 4.1E-18 T 06-07-2017 CAK77_RS13900 32457e054b32da90934c8a0a8ddf3c5e 216 PRINTS PR01100 Shikimate kinase family signature 75 84 4.1E-18 T 06-07-2017 CAK77_RS13900 32457e054b32da90934c8a0a8ddf3c5e 216 PRINTS PR01100 Shikimate kinase family signature 29 42 4.1E-18 T 06-07-2017 CAK77_RS13900 32457e054b32da90934c8a0a8ddf3c5e 216 PRINTS PR01100 Shikimate kinase family signature 5 20 4.1E-18 T 06-07-2017 CAK77_RS13900 32457e054b32da90934c8a0a8ddf3c5e 216 PRINTS PR01100 Shikimate kinase family signature 95 112 4.1E-18 T 06-07-2017 CAK77_RS07190 9871be258914c01e79f2a5df1f9409dd 470 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 43 468 6.1E-148 T 06-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAK77_RS07190 9871be258914c01e79f2a5df1f9409dd 470 Gene3D G3DSA:2.40.37.10 323 468 1.1E-49 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CAK77_RS07190 9871be258914c01e79f2a5df1f9409dd 470 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 92 110 - T 06-07-2017 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site CAK77_RS07190 9871be258914c01e79f2a5df1f9409dd 470 PRINTS PR01181 Diaminopimelate decarboxylase signature 435 457 7.8E-27 T 06-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAK77_RS07190 9871be258914c01e79f2a5df1f9409dd 470 PRINTS PR01181 Diaminopimelate decarboxylase signature 352 370 7.8E-27 T 06-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAK77_RS07190 9871be258914c01e79f2a5df1f9409dd 470 PRINTS PR01181 Diaminopimelate decarboxylase signature 110 127 7.8E-27 T 06-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAK77_RS07190 9871be258914c01e79f2a5df1f9409dd 470 PRINTS PR01181 Diaminopimelate decarboxylase signature 199 208 7.8E-27 T 06-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAK77_RS07190 9871be258914c01e79f2a5df1f9409dd 470 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 350 444 2.6E-15 T 06-07-2017 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 CAK77_RS07190 9871be258914c01e79f2a5df1f9409dd 470 SUPERFAMILY SSF51419 62 331 1.32E-74 T 06-07-2017 IPR029066 PLP-binding barrel CAK77_RS07190 9871be258914c01e79f2a5df1f9409dd 470 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 69 330 2.7E-58 T 06-07-2017 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 CAK77_RS07190 9871be258914c01e79f2a5df1f9409dd 470 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 266 283 - T 06-07-2017 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site CAK77_RS07190 9871be258914c01e79f2a5df1f9409dd 470 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 320 339 6.6E-17 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CAK77_RS07190 9871be258914c01e79f2a5df1f9409dd 470 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 425 438 6.6E-17 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CAK77_RS07190 9871be258914c01e79f2a5df1f9409dd 470 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 112 124 6.6E-17 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CAK77_RS07190 9871be258914c01e79f2a5df1f9409dd 470 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 227 240 6.6E-17 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CAK77_RS07190 9871be258914c01e79f2a5df1f9409dd 470 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 92 110 6.6E-17 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CAK77_RS07190 9871be258914c01e79f2a5df1f9409dd 470 SUPERFAMILY SSF50621 306 468 7.95E-47 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CAK77_RS07190 9871be258914c01e79f2a5df1f9409dd 470 Gene3D G3DSA:3.20.20.10 70 322 7.3E-88 T 06-07-2017 IPR029066 PLP-binding barrel CAK77_RS07190 9871be258914c01e79f2a5df1f9409dd 470 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 51 468 39.799 T 06-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAK77_RS13475 d71b0a31e3ebb0398395f58e4a6a6466 245 Pfam PF12840 Helix-turn-helix domain 31 72 1.1E-6 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS13475 d71b0a31e3ebb0398395f58e4a6a6466 245 SUPERFAMILY SSF46785 29 220 2.69E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS13475 d71b0a31e3ebb0398395f58e4a6a6466 245 Gene3D G3DSA:1.10.10.10 31 137 6.4E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS14715 859f7e8a1efbd65d950deb2693659d7b 189 Gene3D G3DSA:3.40.630.30 4 188 3.9E-25 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS14715 859f7e8a1efbd65d950deb2693659d7b 189 SUPERFAMILY SSF55729 4 188 1.4E-12 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS14715 859f7e8a1efbd65d950deb2693659d7b 189 Pfam PF13673 Acetyltransferase (GNAT) domain 110 174 2.3E-5 T 06-07-2017 IPR000182 GNAT domain GO:0008080 CAK77_RS20515 b3a31b8404f816a230f5475bd28fc4cc 430 TIGRFAM TIGR01346 isocit_lyase: isocitrate lyase 10 253 1.3E-113 T 06-07-2017 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 CAK77_RS20515 b3a31b8404f816a230f5475bd28fc4cc 430 TIGRFAM TIGR01346 isocit_lyase: isocitrate lyase 254 429 5.3E-86 T 06-07-2017 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 CAK77_RS20515 b3a31b8404f816a230f5475bd28fc4cc 430 Pfam PF00463 Isocitrate lyase family 11 253 1.1E-51 T 06-07-2017 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 CAK77_RS20515 b3a31b8404f816a230f5475bd28fc4cc 430 Pfam PF00463 Isocitrate lyase family 255 426 1.2E-45 T 06-07-2017 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 CAK77_RS20515 b3a31b8404f816a230f5475bd28fc4cc 430 Gene3D G3DSA:3.20.20.60 11 411 4.8E-158 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAK77_RS20515 b3a31b8404f816a230f5475bd28fc4cc 430 PIRSF PIRSF001362 1 430 1.8E-231 T 06-07-2017 CAK77_RS20515 b3a31b8404f816a230f5475bd28fc4cc 430 ProSitePatterns PS00161 Isocitrate lyase signature. 191 196 - T 06-07-2017 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824|GO:0008152 CAK77_RS20515 b3a31b8404f816a230f5475bd28fc4cc 430 SUPERFAMILY SSF51621 10 429 1.57E-152 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAK77_RS03695 2b52a1d01e55446895519db7c7c31f41 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 118 138 7.5E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK77_RS03695 2b52a1d01e55446895519db7c7c31f41 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 69 84 7.5E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK77_RS03695 2b52a1d01e55446895519db7c7c31f41 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 52 68 7.5E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK77_RS03695 2b52a1d01e55446895519db7c7c31f41 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 88 104 7.5E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK77_RS03695 2b52a1d01e55446895519db7c7c31f41 154 Gene3D G3DSA:1.10.10.10 6 143 1.1E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS03695 2b52a1d01e55446895519db7c7c31f41 154 SUPERFAMILY SSF46785 7 142 1.25E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS03695 2b52a1d01e55446895519db7c7c31f41 154 SMART SM00347 27 128 5.1E-12 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK77_RS03695 2b52a1d01e55446895519db7c7c31f41 154 Pfam PF01047 MarR family 49 92 1.2E-9 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK77_RS01735 a66c59decbe52565cf784426ecfb81f3 345 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 4 113 7.8E-29 T 06-07-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CAK77_RS01735 a66c59decbe52565cf784426ecfb81f3 345 SUPERFAMILY SSF51735 1 157 3.2E-44 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS01735 a66c59decbe52565cf784426ecfb81f3 345 SMART SM00859 3 118 1.1E-37 T 06-07-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CAK77_RS01735 a66c59decbe52565cf784426ecfb81f3 345 Gene3D G3DSA:3.40.50.720 2 143 7.6E-56 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS01735 a66c59decbe52565cf784426ecfb81f3 345 ProSitePatterns PS01103 Aspartate-semialdehyde dehydrogenase signature. 244 258 - T 06-07-2017 IPR000319 Aspartate-semialdehyde dehydrogenase, conserved site GO:0004073|GO:0006520|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CAK77_RS01735 a66c59decbe52565cf784426ecfb81f3 345 SUPERFAMILY SSF55347 130 330 1.11E-58 T 06-07-2017 CAK77_RS01735 a66c59decbe52565cf784426ecfb81f3 345 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 3 344 1.3E-139 T 06-07-2017 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CAK77_RS01735 a66c59decbe52565cf784426ecfb81f3 345 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 140 329 3.4E-48 T 06-07-2017 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CAK77_RS01735 a66c59decbe52565cf784426ecfb81f3 345 PIRSF PIRSF000148 1 345 2.0E-107 T 06-07-2017 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CAK77_RS01735 a66c59decbe52565cf784426ecfb81f3 345 Gene3D G3DSA:3.30.360.10 144 325 6.1E-68 T 06-07-2017 CAK77_RS01735 a66c59decbe52565cf784426ecfb81f3 345 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 1 343 35.002 T 06-07-2017 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CAK77_RS16280 fbad78bcd6518f8ea58405781e4c9d8f 348 Pfam PF07859 alpha/beta hydrolase fold 115 322 3.4E-74 T 06-07-2017 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CAK77_RS16280 fbad78bcd6518f8ea58405781e4c9d8f 348 Gene3D G3DSA:3.40.50.1820 51 347 3.3E-94 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS16280 fbad78bcd6518f8ea58405781e4c9d8f 348 ProSitePatterns PS01173 Lipolytic enzymes "G-D-X-G" family, putative histidine active site. 115 131 - T 06-07-2017 IPR002168 Lipase, GDXG, putative histidine active site GO:0008152|GO:0016787 Reactome: R-HSA-163560 CAK77_RS16280 fbad78bcd6518f8ea58405781e4c9d8f 348 SUPERFAMILY SSF53474 63 346 3.59E-69 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS20010 c72a9fe998e430f9769d1aed59be9eb7 305 Gene3D G3DSA:3.40.50.1000 129 275 5.7E-49 T 06-07-2017 IPR023214 HAD-like domain CAK77_RS20010 c72a9fe998e430f9769d1aed59be9eb7 305 Pfam PF12710 haloacid dehalogenase-like hydrolase 57 243 2.6E-29 T 06-07-2017 CAK77_RS20010 c72a9fe998e430f9769d1aed59be9eb7 305 SUPERFAMILY SSF56784 56 276 1.16E-30 T 06-07-2017 IPR023214 HAD-like domain CAK77_RS20010 c72a9fe998e430f9769d1aed59be9eb7 305 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 56 257 5.1E-58 T 06-07-2017 IPR006385 HAD-superfamily hydrolase, subfamily IB, PSPase-like, bacterial CAK77_RS20010 c72a9fe998e430f9769d1aed59be9eb7 305 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 56 246 2.3E-18 T 06-07-2017 IPR006383 HAD-superfamily hydrolase, subfamily IB, PSPase-like GO:0008152|GO:0016791 CAK77_RS19625 7a075a319aad49cbe87b2274c36d0060 355 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 129 148 1.1E-6 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK77_RS19625 7a075a319aad49cbe87b2274c36d0060 355 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 70 77 1.1E-6 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK77_RS19625 7a075a319aad49cbe87b2274c36d0060 355 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 153 162 1.1E-6 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK77_RS19625 7a075a319aad49cbe87b2274c36d0060 355 Pfam PF00970 Oxidoreductase FAD-binding domain 22 119 2.5E-9 T 06-07-2017 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 CAK77_RS19625 7a075a319aad49cbe87b2274c36d0060 355 SUPERFAMILY SSF54292 235 348 3.8E-25 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK77_RS19625 7a075a319aad49cbe87b2274c36d0060 355 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 302 310 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CAK77_RS19625 7a075a319aad49cbe87b2274c36d0060 355 PRINTS PR00410 Phenol hydroxylase reductase family signature 129 148 8.7E-11 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 CAK77_RS19625 7a075a319aad49cbe87b2274c36d0060 355 PRINTS PR00410 Phenol hydroxylase reductase family signature 50 62 8.7E-11 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 CAK77_RS19625 7a075a319aad49cbe87b2274c36d0060 355 PRINTS PR00410 Phenol hydroxylase reductase family signature 114 123 8.7E-11 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 CAK77_RS19625 7a075a319aad49cbe87b2274c36d0060 355 PRINTS PR00410 Phenol hydroxylase reductase family signature 213 221 8.7E-11 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 CAK77_RS19625 7a075a319aad49cbe87b2274c36d0060 355 SUPERFAMILY SSF52343 110 243 1.17E-28 T 06-07-2017 CAK77_RS19625 7a075a319aad49cbe87b2274c36d0060 355 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 271 344 6.8E-14 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK77_RS19625 7a075a319aad49cbe87b2274c36d0060 355 Gene3D G3DSA:3.40.50.80 112 238 8.1E-28 T 06-07-2017 CAK77_RS19625 7a075a319aad49cbe87b2274c36d0060 355 SUPERFAMILY SSF63380 16 119 6.81E-24 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CAK77_RS19625 7a075a319aad49cbe87b2274c36d0060 355 Gene3D G3DSA:2.40.30.10 19 111 5.3E-26 T 06-07-2017 CAK77_RS19625 7a075a319aad49cbe87b2274c36d0060 355 Gene3D G3DSA:3.10.20.30 239 349 9.7E-30 T 06-07-2017 IPR012675 Beta-grasp domain CAK77_RS19625 7a075a319aad49cbe87b2274c36d0060 355 Pfam PF00175 Oxidoreductase NAD-binding domain 130 227 2.6E-11 T 06-07-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CAK77_RS21980 b852420a69cd1c65b0b67b5ad384a757 175 Hamap MF_01676 Alkyl hydroperoxide reductase AhpD [ahpD]. 1 175 79.279 T 06-07-2017 IPR004674 Alkylhydroperoxidase AhpD GO:0006979|GO:0032843|GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CAK77_RS21980 b852420a69cd1c65b0b67b5ad384a757 175 Gene3D G3DSA:1.20.1290.10 2 171 4.8E-55 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAK77_RS21980 b852420a69cd1c65b0b67b5ad384a757 175 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 111 159 3.8E-19 T 06-07-2017 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CAK77_RS21980 b852420a69cd1c65b0b67b5ad384a757 175 SUPERFAMILY SSF69118 3 173 2.62E-48 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAK77_RS21980 b852420a69cd1c65b0b67b5ad384a757 175 Pfam PF02627 Carboxymuconolactone decarboxylase family 101 174 5.1E-18 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CAK77_RS21980 b852420a69cd1c65b0b67b5ad384a757 175 TIGRFAM TIGR00777 ahpD: alkylhydroperoxidase, AhpD family 2 174 8.2E-77 T 06-07-2017 IPR004674 Alkylhydroperoxidase AhpD GO:0006979|GO:0032843|GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CAK77_RS11785 96061d4e5bdbdaabc874cb42413384e7 230 Gene3D G3DSA:3.40.50.300 26 219 3.9E-20 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS11785 96061d4e5bdbdaabc874cb42413384e7 230 TIGRFAM TIGR00101 ureG: urease accessory protein UreG 27 219 2.4E-83 T 06-07-2017 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 CAK77_RS11785 96061d4e5bdbdaabc874cb42413384e7 230 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 29 197 1.7E-34 T 06-07-2017 IPR003495 CobW/HypB/UreG, nucleotide-binding domain CAK77_RS11785 96061d4e5bdbdaabc874cb42413384e7 230 SUPERFAMILY SSF52540 21 227 7.37E-36 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS11785 96061d4e5bdbdaabc874cb42413384e7 230 Hamap MF_01389 Urease accessory protein UreG [ureG]. 25 223 43.383 T 06-07-2017 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 CAK77_RS11785 96061d4e5bdbdaabc874cb42413384e7 230 PIRSF PIRSF005624 9 230 1.6E-44 T 06-07-2017 CAK77_RS00425 0b3278c3b9e86bf53ca5e2b697fe6b03 151 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 39 147 5.2E-27 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CAK77_RS00425 0b3278c3b9e86bf53ca5e2b697fe6b03 151 Pfam PF04075 Domain of unknown function (DUF385) 27 147 9.2E-31 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CAK77_RS13735 7ba3442995bf0475ed2b411b5fd14616 227 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 135 157 - T 06-07-2017 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 CAK77_RS13735 7ba3442995bf0475ed2b411b5fd14616 227 Pfam PF00834 Ribulose-phosphate 3 epimerase family 8 202 1.8E-82 T 06-07-2017 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 CAK77_RS13735 7ba3442995bf0475ed2b411b5fd14616 227 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 33 47 - T 06-07-2017 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 CAK77_RS13735 7ba3442995bf0475ed2b411b5fd14616 227 Gene3D G3DSA:3.20.20.70 5 222 5.9E-93 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK77_RS13735 7ba3442995bf0475ed2b411b5fd14616 227 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 7 215 5.2E-85 T 06-07-2017 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 CAK77_RS13735 7ba3442995bf0475ed2b411b5fd14616 227 PIRSF PIRSF001461 2 226 5.1E-96 T 06-07-2017 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 CAK77_RS13735 7ba3442995bf0475ed2b411b5fd14616 227 SUPERFAMILY SSF51366 7 217 3.2E-67 T 06-07-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CAK77_RS24270 f472315dfe6c41036561af2db46dafba 255 Pfam PF01925 Sulfite exporter TauE/SafE 10 248 1.3E-31 T 06-07-2017 IPR002781 Transmembrane protein TauE-like GO:0016021 CAK77_RS12115 c0c0742988c21a37f56a3d3117a59a5b 538 Pfam PF00667 FAD binding domain 301 364 2.0E-10 T 06-07-2017 IPR003097 FAD-binding, type 1 GO:0016491|GO:0055114 CAK77_RS12115 c0c0742988c21a37f56a3d3117a59a5b 538 Pfam PF00667 FAD binding domain 174 240 5.4E-13 T 06-07-2017 IPR003097 FAD-binding, type 1 GO:0016491|GO:0055114 CAK77_RS12115 c0c0742988c21a37f56a3d3117a59a5b 538 Pfam PF00175 Oxidoreductase NAD-binding domain 393 502 1.3E-17 T 06-07-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CAK77_RS12115 c0c0742988c21a37f56a3d3117a59a5b 538 SUPERFAMILY SSF52343 382 538 5.89E-47 T 06-07-2017 CAK77_RS12115 c0c0742988c21a37f56a3d3117a59a5b 538 Gene3D G3DSA:3.40.50.360 8 151 1.4E-39 T 06-07-2017 IPR029039 Flavoprotein-like domain CAK77_RS12115 c0c0742988c21a37f56a3d3117a59a5b 538 Gene3D G3DSA:1.20.990.10 224 323 9.7E-11 T 06-07-2017 IPR023173 NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain-3 GO:0016491|GO:0055114 CAK77_RS12115 c0c0742988c21a37f56a3d3117a59a5b 538 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 417 426 1.2E-29 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK77_RS12115 c0c0742988c21a37f56a3d3117a59a5b 538 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 464 480 1.2E-29 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK77_RS12115 c0c0742988c21a37f56a3d3117a59a5b 538 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 487 495 1.2E-29 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK77_RS12115 c0c0742988c21a37f56a3d3117a59a5b 538 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 392 411 1.2E-29 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK77_RS12115 c0c0742988c21a37f56a3d3117a59a5b 538 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 326 333 1.2E-29 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK77_RS12115 c0c0742988c21a37f56a3d3117a59a5b 538 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 430 441 1.2E-29 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK77_RS12115 c0c0742988c21a37f56a3d3117a59a5b 538 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 359 368 1.2E-29 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK77_RS12115 c0c0742988c21a37f56a3d3117a59a5b 538 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 212 222 1.2E-29 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAK77_RS12115 c0c0742988c21a37f56a3d3117a59a5b 538 Pfam PF00258 Flavodoxin 11 134 3.7E-28 T 06-07-2017 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 CAK77_RS12115 c0c0742988c21a37f56a3d3117a59a5b 538 SUPERFAMILY SSF52218 8 151 1.26E-41 T 06-07-2017 IPR029039 Flavoprotein-like domain CAK77_RS12115 c0c0742988c21a37f56a3d3117a59a5b 538 Gene3D G3DSA:2.40.30.10 174 222 7.1E-32 T 06-07-2017 CAK77_RS12115 c0c0742988c21a37f56a3d3117a59a5b 538 Gene3D G3DSA:2.40.30.10 324 393 7.1E-32 T 06-07-2017 CAK77_RS12115 c0c0742988c21a37f56a3d3117a59a5b 538 PRINTS PR00369 Flavodoxin signature 10 23 2.0E-12 T 06-07-2017 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 CAK77_RS12115 c0c0742988c21a37f56a3d3117a59a5b 538 PRINTS PR00369 Flavodoxin signature 115 134 2.0E-12 T 06-07-2017 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 CAK77_RS12115 c0c0742988c21a37f56a3d3117a59a5b 538 PRINTS PR00369 Flavodoxin signature 59 70 2.0E-12 T 06-07-2017 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 CAK77_RS12115 c0c0742988c21a37f56a3d3117a59a5b 538 PRINTS PR00369 Flavodoxin signature 91 101 2.0E-12 T 06-07-2017 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 CAK77_RS12115 c0c0742988c21a37f56a3d3117a59a5b 538 SUPERFAMILY SSF63380 174 383 2.93E-49 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CAK77_RS12115 c0c0742988c21a37f56a3d3117a59a5b 538 Gene3D G3DSA:3.40.50.80 394 537 1.1E-55 T 06-07-2017 CAK77_RS22080 3f32601e9e8cf15230aef55657fe0ce9 155 SMART SM00418 22 104 0.0066 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK77_RS22080 3f32601e9e8cf15230aef55657fe0ce9 155 Pfam PF01638 HxlR-like helix-turn-helix 27 115 1.7E-15 T 06-07-2017 IPR002577 Helix-turn-helix, HxlR type CAK77_RS22080 3f32601e9e8cf15230aef55657fe0ce9 155 SUPERFAMILY SSF46785 13 126 2.13E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS22080 3f32601e9e8cf15230aef55657fe0ce9 155 Gene3D G3DSA:1.10.10.10 11 118 1.6E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS15875 1af58d3144ee2549b443f00ba6038788 192 Pfam PF04973 Nicotinamide mononucleotide transporter 2 181 4.1E-51 T 06-07-2017 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 CAK77_RS15875 1af58d3144ee2549b443f00ba6038788 192 TIGRFAM TIGR01528 NMN_trans_PnuC: nicotinamide mononucleotide transporter PnuC 2 182 6.1E-27 T 06-07-2017 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 CAK77_RS04585 1d01382257af1241e007836d7761d1c3 212 Hamap MF_01629 Pyridoxine/pyridoxamine 5'-phosphate oxidase [pdxH]. 8 212 34.262 T 06-07-2017 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAK77_RS04585 1d01382257af1241e007836d7761d1c3 212 ProSitePatterns PS01064 Pyridoxamine 5'-phosphate oxidase signature. 186 199 - T 06-07-2017 IPR019740 Pyridoxamine 5'-phosphate oxidase, conserved site GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAK77_RS04585 1d01382257af1241e007836d7761d1c3 212 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 41 121 6.6E-21 T 06-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAK77_RS04585 1d01382257af1241e007836d7761d1c3 212 Gene3D G3DSA:2.30.110.10 21 203 3.0E-71 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS04585 1d01382257af1241e007836d7761d1c3 212 TIGRFAM TIGR00558 pdxH: pyridoxamine 5'-phosphate oxidase 25 202 8.2E-62 T 06-07-2017 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAK77_RS04585 1d01382257af1241e007836d7761d1c3 212 Pfam PF10590 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region 176 212 2.6E-13 T 06-07-2017 IPR019576 Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAK77_RS04585 1d01382257af1241e007836d7761d1c3 212 PIRSF PIRSF000190 8 212 4.3E-68 T 06-07-2017 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAK77_RS04585 1d01382257af1241e007836d7761d1c3 212 SUPERFAMILY SSF50475 17 212 3.39E-62 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS01255 e3f2258fe656129c9c9ee3e54be0a9bd 347 Pfam PF00155 Aminotransferase class I and II 25 335 3.9E-52 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAK77_RS01255 e3f2258fe656129c9c9ee3e54be0a9bd 347 Hamap MF_01513 Putative phenylalanine aminotransferase [pat]. 5 347 45.616 T 06-07-2017 IPR024892 Putative phenylalanine aminotransferase CAK77_RS01255 e3f2258fe656129c9c9ee3e54be0a9bd 347 Gene3D G3DSA:3.90.1150.10 235 345 2.6E-33 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK77_RS01255 e3f2258fe656129c9c9ee3e54be0a9bd 347 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 6 343 2.0E-85 T 06-07-2017 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 CAK77_RS01255 e3f2258fe656129c9c9ee3e54be0a9bd 347 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 211 220 - T 06-07-2017 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 CAK77_RS01255 e3f2258fe656129c9c9ee3e54be0a9bd 347 Gene3D G3DSA:3.40.640.10 39 234 1.6E-46 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK77_RS01255 e3f2258fe656129c9c9ee3e54be0a9bd 347 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 4 347 48.397 T 06-07-2017 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 CAK77_RS01255 e3f2258fe656129c9c9ee3e54be0a9bd 347 SUPERFAMILY SSF53383 16 342 2.45E-77 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK77_RS14430 7c89997713736b3945e322234ef1dbc8 543 SUPERFAMILY SSF56112 48 314 2.55E-12 T 06-07-2017 IPR011009 Protein kinase-like domain CAK77_RS14430 7c89997713736b3945e322234ef1dbc8 543 Gene3D G3DSA:3.40.50.300 354 526 1.4E-19 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS14430 7c89997713736b3945e322234ef1dbc8 543 Pfam PF13671 AAA domain 358 498 2.7E-16 T 06-07-2017 CAK77_RS14430 7c89997713736b3945e322234ef1dbc8 543 SUPERFAMILY SSF52540 355 526 1.12E-19 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS17745 c3ee2c7c30f022c4fb1fad4dc84df5eb 102 TIGRFAM TIGR02949 anti_SigH_actin: anti-sigma factor, TIGR02949 family 18 95 6.4E-29 T 06-07-2017 IPR014295 Anti-sigma factor CAK77_RS17745 c3ee2c7c30f022c4fb1fad4dc84df5eb 102 Pfam PF13490 Putative zinc-finger 21 54 4.3E-9 T 06-07-2017 IPR027383 Putative zinc-finger CAK77_RS17745 c3ee2c7c30f022c4fb1fad4dc84df5eb 102 TIGRFAM TIGR03988 antisig_RsrA: mycothiol system anti-sigma-R factor 21 95 5.7E-32 T 06-07-2017 IPR024020 Anti sigma-R factor, mycothiol system,RsrA CAK77_RS00170 b5e319f9d6581d04cb339630b790718e 195 Gene3D G3DSA:2.60.40.1240 24 152 1.9E-52 T 06-07-2017 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain CAK77_RS00170 b5e319f9d6581d04cb339630b790718e 195 Pfam PF09167 Domain of unknown function (DUF1942) 27 151 5.3E-48 T 06-07-2017 IPR015250 MPT63-like GO:0005615 CAK77_RS00170 b5e319f9d6581d04cb339630b790718e 195 SUPERFAMILY SSF81982 24 153 5.36E-52 T 06-07-2017 IPR015250 MPT63-like GO:0005615 CAK77_RS00170 b5e319f9d6581d04cb339630b790718e 195 ProDom PD886639 ANTIGEN IMMUNOGENIC EXTRACELLULAR MPT63 MPB63 PRECURSOR IMMUNOPROTECTIVE SIGNAL SEQUENCING DIRECT 44 151 2.0E-24 T 06-07-2017 IPR015250 MPT63-like GO:0005615 CAK77_RS02420 b5e319f9d6581d04cb339630b790718e 195 Gene3D G3DSA:2.60.40.1240 24 152 1.9E-52 T 06-07-2017 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain CAK77_RS02420 b5e319f9d6581d04cb339630b790718e 195 Pfam PF09167 Domain of unknown function (DUF1942) 27 151 5.3E-48 T 06-07-2017 IPR015250 MPT63-like GO:0005615 CAK77_RS02420 b5e319f9d6581d04cb339630b790718e 195 SUPERFAMILY SSF81982 24 153 5.36E-52 T 06-07-2017 IPR015250 MPT63-like GO:0005615 CAK77_RS02420 b5e319f9d6581d04cb339630b790718e 195 ProDom PD886639 ANTIGEN IMMUNOGENIC EXTRACELLULAR MPT63 MPB63 PRECURSOR IMMUNOPROTECTIVE SIGNAL SEQUENCING DIRECT 44 151 2.0E-24 T 06-07-2017 IPR015250 MPT63-like GO:0005615 CAK77_RS09185 35a3e97d0d6130b8146ca76c4578b69d 314 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 313 86.404 T 06-07-2017 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 CAK77_RS09185 35a3e97d0d6130b8146ca76c4578b69d 314 Pfam PF03186 CobD/Cbib protein 12 292 2.2E-85 T 06-07-2017 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 CAK77_RS09185 35a3e97d0d6130b8146ca76c4578b69d 314 TIGRFAM TIGR00380 cobD: cobalamin biosynthesis protein CobD 17 266 1.9E-52 T 06-07-2017 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 CAK77_RS13825 8741e939a01a44161f09f3a3d69f2f21 1112 SMART SM01096 427 550 2.2E-58 T 06-07-2017 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAK77_RS13825 8741e939a01a44161f09f3a3d69f2f21 1112 Pfam PF02142 MGS-like domain 987 1079 1.3E-21 T 06-07-2017 IPR011607 Methylglyoxal synthase-like domain CAK77_RS13825 8741e939a01a44161f09f3a3d69f2f21 1112 SUPERFAMILY SSF48108 401 553 4.58E-41 T 06-07-2017 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAK77_RS13825 8741e939a01a44161f09f3a3d69f2f21 1112 SUPERFAMILY SSF52440 1 132 4.89E-42 T 06-07-2017 IPR016185 Pre-ATP-grasp domain CAK77_RS13825 8741e939a01a44161f09f3a3d69f2f21 1112 Gene3D G3DSA:1.10.1030.10 405 539 3.9E-43 T 06-07-2017 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAK77_RS13825 8741e939a01a44161f09f3a3d69f2f21 1112 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1100 12.782 T 06-07-2017 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAK77_RS13825 8741e939a01a44161f09f3a3d69f2f21 1112 Gene3D G3DSA:3.30.470.20 205 404 6.4E-75 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAK77_RS13825 8741e939a01a44161f09f3a3d69f2f21 1112 Gene3D G3DSA:3.30.470.20 762 965 7.4E-68 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAK77_RS13825 8741e939a01a44161f09f3a3d69f2f21 1112 SMART SM00851 986 1079 2.3E-24 T 06-07-2017 IPR011607 Methylglyoxal synthase-like domain CAK77_RS13825 8741e939a01a44161f09f3a3d69f2f21 1112 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 7.0E-61 T 06-07-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAK77_RS13825 8741e939a01a44161f09f3a3d69f2f21 1112 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 209 228 7.0E-61 T 06-07-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAK77_RS13825 8741e939a01a44161f09f3a3d69f2f21 1112 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 384 402 7.0E-61 T 06-07-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAK77_RS13825 8741e939a01a44161f09f3a3d69f2f21 1112 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 244 261 7.0E-61 T 06-07-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAK77_RS13825 8741e939a01a44161f09f3a3d69f2f21 1112 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 302 331 7.0E-61 T 06-07-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAK77_RS13825 8741e939a01a44161f09f3a3d69f2f21 1112 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 7.0E-61 T 06-07-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAK77_RS13825 8741e939a01a44161f09f3a3d69f2f21 1112 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 173 185 7.0E-61 T 06-07-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAK77_RS13825 8741e939a01a44161f09f3a3d69f2f21 1112 Gene3D G3DSA:3.40.50.20 4 112 9.7E-38 T 06-07-2017 IPR016185 Pre-ATP-grasp domain CAK77_RS13825 8741e939a01a44161f09f3a3d69f2f21 1112 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 302 309 - T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CAK77_RS13825 8741e939a01a44161f09f3a3d69f2f21 1112 Gene3D G3DSA:3.40.50.20 540 677 1.6E-54 T 06-07-2017 IPR016185 Pre-ATP-grasp domain CAK77_RS13825 8741e939a01a44161f09f3a3d69f2f21 1112 SUPERFAMILY SSF56059 689 964 9.19E-94 T 06-07-2017 CAK77_RS13825 8741e939a01a44161f09f3a3d69f2f21 1112 SUPERFAMILY SSF56059 133 405 1.77E-100 T 06-07-2017 CAK77_RS13825 8741e939a01a44161f09f3a3d69f2f21 1112 SUPERFAMILY SSF52440 564 690 2.45E-43 T 06-07-2017 IPR016185 Pre-ATP-grasp domain CAK77_RS13825 8741e939a01a44161f09f3a3d69f2f21 1112 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 725 739 - T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CAK77_RS13825 8741e939a01a44161f09f3a3d69f2f21 1112 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 133 339 7.9E-65 T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CAK77_RS13825 8741e939a01a44161f09f3a3d69f2f21 1112 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 689 889 9.8E-34 T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CAK77_RS13825 8741e939a01a44161f09f3a3d69f2f21 1112 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 854 861 - T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CAK77_RS13825 8741e939a01a44161f09f3a3d69f2f21 1112 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1089 0.0 T 06-07-2017 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAK77_RS13825 8741e939a01a44161f09f3a3d69f2f21 1112 Gene3D G3DSA:3.40.50.1380 968 1109 5.1E-41 T 06-07-2017 IPR011607 Methylglyoxal synthase-like domain CAK77_RS13825 8741e939a01a44161f09f3a3d69f2f21 1112 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 430 550 1.2E-37 T 06-07-2017 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAK77_RS13825 8741e939a01a44161f09f3a3d69f2f21 1112 SUPERFAMILY SSF52335 973 1109 1.44E-33 T 06-07-2017 IPR011607 Methylglyoxal synthase-like domain CAK77_RS13825 8741e939a01a44161f09f3a3d69f2f21 1112 Gene3D G3DSA:3.30.1490.20 148 204 5.8E-19 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CAK77_RS13825 8741e939a01a44161f09f3a3d69f2f21 1112 Gene3D G3DSA:3.30.1490.20 702 761 8.9E-27 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CAK77_RS13080 2e818dd925edf1022206cd822bc13535 207 SUPERFAMILY SSF54211 93 192 1.77E-27 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAK77_RS13080 2e818dd925edf1022206cd822bc13535 207 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 8 207 41.07 T 06-07-2017 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 CAK77_RS13080 2e818dd925edf1022206cd822bc13535 207 Gene3D G3DSA:3.30.230.40 96 207 4.1E-29 T 06-07-2017 CAK77_RS13080 2e818dd925edf1022206cd822bc13535 207 SUPERFAMILY SSF54211 8 92 9.61E-32 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAK77_RS13080 2e818dd925edf1022206cd822bc13535 207 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 67 80 - T 06-07-2017 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 CAK77_RS13080 2e818dd925edf1022206cd822bc13535 207 Gene3D G3DSA:3.30.230.40 8 95 4.9E-36 T 06-07-2017 CAK77_RS13080 2e818dd925edf1022206cd822bc13535 207 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 37 187 2.0E-56 T 06-07-2017 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 CAK77_RS13080 2e818dd925edf1022206cd822bc13535 207 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 169 181 - T 06-07-2017 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 CAK77_RS23890 1bab208e62e55e99a201ee985e6962ca 298 Pfam PF03466 LysR substrate binding domain 105 289 8.7E-21 T 06-07-2017 IPR005119 LysR, substrate-binding CAK77_RS23890 1bab208e62e55e99a201ee985e6962ca 298 Gene3D G3DSA:3.40.190.10 189 275 4.6E-13 T 06-07-2017 CAK77_RS23890 1bab208e62e55e99a201ee985e6962ca 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 15 74 4.3E-20 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK77_RS23890 1bab208e62e55e99a201ee985e6962ca 298 Gene3D G3DSA:1.10.10.10 13 94 1.9E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS23890 1bab208e62e55e99a201ee985e6962ca 298 SUPERFAMILY SSF53850 105 291 1.27E-20 T 06-07-2017 CAK77_RS23890 1bab208e62e55e99a201ee985e6962ca 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 51 8.9E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK77_RS23890 1bab208e62e55e99a201ee985e6962ca 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 41 8.9E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK77_RS23890 1bab208e62e55e99a201ee985e6962ca 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 51 62 8.9E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK77_RS23890 1bab208e62e55e99a201ee985e6962ca 298 SUPERFAMILY SSF46785 12 95 1.36E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS23890 1bab208e62e55e99a201ee985e6962ca 298 Gene3D G3DSA:3.40.190.10 107 188 5.2E-9 T 06-07-2017 CAK77_RS06015 f7de3afba8f64e49155e0db41cc31286 223 Gene3D G3DSA:1.10.3630.10 3 217 4.6E-18 T 06-07-2017 CAK77_RS06015 f7de3afba8f64e49155e0db41cc31286 223 Pfam PF05719 Golgi phosphoprotein 3 (GPP34) 4 197 1.9E-32 T 06-07-2017 IPR008628 Golgi phosphoprotein 3 GO:0048193|GO:0070273 CAK77_RS19505 710a5d5bbc2f08601338c9c4256b94f4 285 Pfam PF00582 Universal stress protein family 11 137 3.4E-18 T 06-07-2017 IPR006016 UspA GO:0006950 CAK77_RS19505 710a5d5bbc2f08601338c9c4256b94f4 285 PRINTS PR01438 Universal stress protein signature 97 109 2.8E-8 T 06-07-2017 IPR006015 Universal stress protein A CAK77_RS19505 710a5d5bbc2f08601338c9c4256b94f4 285 PRINTS PR01438 Universal stress protein signature 115 137 2.8E-8 T 06-07-2017 IPR006015 Universal stress protein A CAK77_RS19505 710a5d5bbc2f08601338c9c4256b94f4 285 PRINTS PR01438 Universal stress protein signature 8 26 2.8E-8 T 06-07-2017 IPR006015 Universal stress protein A CAK77_RS19505 710a5d5bbc2f08601338c9c4256b94f4 285 SUPERFAMILY SSF52402 148 278 2.09E-7 T 06-07-2017 CAK77_RS19505 710a5d5bbc2f08601338c9c4256b94f4 285 Gene3D G3DSA:3.40.50.620 11 137 7.0E-23 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS19505 710a5d5bbc2f08601338c9c4256b94f4 285 Gene3D G3DSA:3.40.50.620 147 279 2.3E-5 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS19505 710a5d5bbc2f08601338c9c4256b94f4 285 SUPERFAMILY SSF52402 11 140 1.0E-22 T 06-07-2017 CAK77_RS15720 b3a1d9e45b556fd5e5858cef4a3dbde4 489 Gene3D G3DSA:3.50.50.60 2 70 8.9E-16 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS15720 b3a1d9e45b556fd5e5858cef4a3dbde4 489 Gene3D G3DSA:3.50.50.60 145 327 8.9E-16 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS15720 b3a1d9e45b556fd5e5858cef4a3dbde4 489 SUPERFAMILY SSF51905 3 270 1.91E-21 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS15720 b3a1d9e45b556fd5e5858cef4a3dbde4 489 Pfam PF06039 Malate:quinone oxidoreductase (Mqo) 3 487 3.2E-212 T 06-07-2017 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 CAK77_RS15720 b3a1d9e45b556fd5e5858cef4a3dbde4 489 TIGRFAM TIGR01320 mal_quin_oxido: malate dehydrogenase (acceptor) 4 485 2.2E-231 T 06-07-2017 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 CAK77_RS15720 b3a1d9e45b556fd5e5858cef4a3dbde4 489 Hamap MF_00212 Probable malate:quinone oxidoreductase [mqo]. 1 487 49.428 T 06-07-2017 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 CAK77_RS08300 9890223f27a61ae90b075751ebdd1567 503 Pfam PF03772 Competence protein 217 481 9.6E-48 T 06-07-2017 IPR004477 ComEC/Rec2-related protein CAK77_RS08300 9890223f27a61ae90b075751ebdd1567 503 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 239 401 1.3E-16 T 06-07-2017 IPR004477 ComEC/Rec2-related protein CAK77_RS06690 e4f9417513ddfbc9eb882a4fb11e7776 321 SUPERFAMILY SSF52266 61 318 1.57E-62 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAK77_RS06690 e4f9417513ddfbc9eb882a4fb11e7776 321 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 66 303 3.1E-18 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAK77_RS06690 e4f9417513ddfbc9eb882a4fb11e7776 321 Gene3D G3DSA:3.40.50.1110 58 318 3.7E-57 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAK77_RS10195 a18d75ece1f0fbb8fae0a4221e3129de 481 SMART SM00382 225 393 1.9E-4 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS10195 a18d75ece1f0fbb8fae0a4221e3129de 481 SUPERFAMILY SSF52540 182 447 3.12E-21 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS10195 a18d75ece1f0fbb8fae0a4221e3129de 481 Pfam PF01580 FtsK/SpoIIIE family 214 397 1.3E-17 T 06-07-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CAK77_RS10195 a18d75ece1f0fbb8fae0a4221e3129de 481 Gene3D G3DSA:3.40.50.300 213 446 9.6E-18 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS09465 75f4da0dbb8f38daa0631d16d5c9a834 364 Gene3D G3DSA:3.30.70.1400 55 135 1.0E-26 T 06-07-2017 CAK77_RS09465 75f4da0dbb8f38daa0631d16d5c9a834 364 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 7 359 1.3E-92 T 06-07-2017 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 CAK77_RS09465 75f4da0dbb8f38daa0631d16d5c9a834 364 Gene3D G3DSA:3.30.1360.120 142 234 2.9E-45 T 06-07-2017 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 CAK77_RS09465 75f4da0dbb8f38daa0631d16d5c9a834 364 Gene3D G3DSA:3.30.1360.120 8 54 2.9E-45 T 06-07-2017 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 CAK77_RS09465 75f4da0dbb8f38daa0631d16d5c9a834 364 Pfam PF01571 Aminomethyltransferase folate-binding domain 9 257 1.3E-82 T 06-07-2017 IPR006222 Glycine cleavage T-protein-like, N-terminal CAK77_RS09465 75f4da0dbb8f38daa0631d16d5c9a834 364 SUPERFAMILY SSF101790 271 360 1.49E-23 T 06-07-2017 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain CAK77_RS09465 75f4da0dbb8f38daa0631d16d5c9a834 364 SUPERFAMILY SSF103025 3 278 5.34E-89 T 06-07-2017 CAK77_RS09465 75f4da0dbb8f38daa0631d16d5c9a834 364 Gene3D G3DSA:2.40.30.110 280 360 4.0E-24 T 06-07-2017 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CAK77_RS09465 75f4da0dbb8f38daa0631d16d5c9a834 364 Hamap MF_00259 Aminomethyltransferase [gcvT]. 3 361 40.047 T 06-07-2017 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CAK77_RS09465 75f4da0dbb8f38daa0631d16d5c9a834 364 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 264 356 3.0E-22 T 06-07-2017 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CAK77_RS09465 75f4da0dbb8f38daa0631d16d5c9a834 364 PIRSF PIRSF006487 2 363 4.4E-84 T 06-07-2017 IPR028896 Aminomethyltransferase/Dimethylsulfonioproprionate demethylase DmdA KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 CAK77_RS16065 c8300eea225f8ef7133846c4736cdda2 158 SUPERFAMILY SSF54565 2 94 2.75E-31 T 06-07-2017 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS16065 c8300eea225f8ef7133846c4736cdda2 158 TIGRFAM TIGR00002 S16: ribosomal protein bS16 3 79 6.4E-29 T 06-07-2017 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS16065 c8300eea225f8ef7133846c4736cdda2 158 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 2 77 21.855 T 06-07-2017 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS16065 c8300eea225f8ef7133846c4736cdda2 158 Pfam PF00886 Ribosomal protein S16 9 67 1.3E-21 T 06-07-2017 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS16065 c8300eea225f8ef7133846c4736cdda2 158 ProSitePatterns PS00732 Ribosomal protein S16 signature. 3 12 - T 06-07-2017 IPR020592 Ribosomal protein S16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS16065 c8300eea225f8ef7133846c4736cdda2 158 Gene3D G3DSA:3.30.1320.10 2 83 5.0E-30 T 06-07-2017 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS03135 5903b08fb87ca10d05c9e47ba1d59072 293 Pfam PF01144 Coenzyme A transferase 6 233 1.1E-39 T 06-07-2017 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 CAK77_RS03135 5903b08fb87ca10d05c9e47ba1d59072 293 SUPERFAMILY SSF100950 3 279 3.98E-63 T 06-07-2017 CAK77_RS03135 5903b08fb87ca10d05c9e47ba1d59072 293 Gene3D G3DSA:3.40.1080.10 162 286 2.6E-69 T 06-07-2017 CAK77_RS03135 5903b08fb87ca10d05c9e47ba1d59072 293 Gene3D G3DSA:3.40.1080.10 3 118 2.6E-69 T 06-07-2017 CAK77_RS03135 5903b08fb87ca10d05c9e47ba1d59072 293 SMART SM00882 5 233 6.4E-21 T 06-07-2017 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 CAK77_RS11395 d6915cac987406dc969e13e530e0ac8f 162 Gene3D G3DSA:1.10.10.10 8 78 1.9E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS11395 d6915cac987406dc969e13e530e0ac8f 162 PRINTS PR01467 Bacterial arginine repressor signature 28 41 4.2E-27 T 06-07-2017 IPR001669 Arginine repressor GO:0003700|GO:0006355 CAK77_RS11395 d6915cac987406dc969e13e530e0ac8f 162 PRINTS PR01467 Bacterial arginine repressor signature 131 146 4.2E-27 T 06-07-2017 IPR001669 Arginine repressor GO:0003700|GO:0006355 CAK77_RS11395 d6915cac987406dc969e13e530e0ac8f 162 PRINTS PR01467 Bacterial arginine repressor signature 44 59 4.2E-27 T 06-07-2017 IPR001669 Arginine repressor GO:0003700|GO:0006355 CAK77_RS11395 d6915cac987406dc969e13e530e0ac8f 162 PRINTS PR01467 Bacterial arginine repressor signature 101 114 4.2E-27 T 06-07-2017 IPR001669 Arginine repressor GO:0003700|GO:0006355 CAK77_RS11395 d6915cac987406dc969e13e530e0ac8f 162 TIGRFAM TIGR01529 argR_whole: arginine repressor 12 161 1.4E-46 T 06-07-2017 IPR001669 Arginine repressor GO:0003700|GO:0006355 CAK77_RS11395 d6915cac987406dc969e13e530e0ac8f 162 SUPERFAMILY SSF46785 9 77 3.03E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS11395 d6915cac987406dc969e13e530e0ac8f 162 Gene3D G3DSA:3.30.1360.40 86 161 2.5E-28 T 06-07-2017 IPR024946 Arginine repressor C-terminal-like domain CAK77_RS11395 d6915cac987406dc969e13e530e0ac8f 162 Hamap MF_00173 Arginine repressor [argR]. 1 162 62.775 T 06-07-2017 IPR001669 Arginine repressor GO:0003700|GO:0006355 CAK77_RS11395 d6915cac987406dc969e13e530e0ac8f 162 Pfam PF02863 Arginine repressor, C-terminal domain 94 159 2.5E-24 T 06-07-2017 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 CAK77_RS11395 d6915cac987406dc969e13e530e0ac8f 162 Pfam PF01316 Arginine repressor, DNA binding domain 10 77 5.3E-23 T 06-07-2017 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 CAK77_RS11395 d6915cac987406dc969e13e530e0ac8f 162 SUPERFAMILY SSF55252 93 160 1.31E-17 T 06-07-2017 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 CAK77_RS11395 d6915cac987406dc969e13e530e0ac8f 162 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 101 159 3.0E-22 T 06-07-2017 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 CAK77_RS17290 4d216fa57a2fe1762f97f907aaf88dd2 141 Pfam PF00293 NUDIX domain 11 122 1.6E-14 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 CAK77_RS17290 4d216fa57a2fe1762f97f907aaf88dd2 141 SUPERFAMILY SSF55811 5 127 3.52E-22 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAK77_RS17290 4d216fa57a2fe1762f97f907aaf88dd2 141 Gene3D G3DSA:3.90.79.10 5 124 5.4E-21 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAK77_RS07760 547dcb3c298c2cfee1c2d4f18200f082 455 Pfam PF00375 Sodium:dicarboxylate symporter family 24 416 6.1E-99 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CAK77_RS07760 547dcb3c298c2cfee1c2d4f18200f082 455 SUPERFAMILY SSF118215 24 416 6.28E-101 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CAK77_RS07760 547dcb3c298c2cfee1c2d4f18200f082 455 PRINTS PR00173 Glutamate-aspartate symporter signature 159 181 1.6E-26 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CAK77_RS07760 547dcb3c298c2cfee1c2d4f18200f082 455 PRINTS PR00173 Glutamate-aspartate symporter signature 206 225 1.6E-26 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CAK77_RS07760 547dcb3c298c2cfee1c2d4f18200f082 455 PRINTS PR00173 Glutamate-aspartate symporter signature 307 333 1.6E-26 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CAK77_RS07760 547dcb3c298c2cfee1c2d4f18200f082 455 PRINTS PR00173 Glutamate-aspartate symporter signature 89 114 1.6E-26 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CAK77_RS07760 547dcb3c298c2cfee1c2d4f18200f082 455 PRINTS PR00173 Glutamate-aspartate symporter signature 22 42 1.6E-26 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CAK77_RS07760 547dcb3c298c2cfee1c2d4f18200f082 455 PRINTS PR00173 Glutamate-aspartate symporter signature 342 361 1.6E-26 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CAK77_RS07760 547dcb3c298c2cfee1c2d4f18200f082 455 Gene3D G3DSA:1.10.3860.10 19 421 4.2E-102 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CAK77_RS00420 05fa88683808b1e318f8d7113aaaccd9 348 Pfam PF11583 P-aminobenzoate N-oxygenase AurF 17 298 4.2E-77 T 06-07-2017 IPR025859 P-aminobenzoate N-oxygenase AurF CAK77_RS00420 05fa88683808b1e318f8d7113aaaccd9 348 SUPERFAMILY SSF47240 27 254 1.07E-6 T 06-07-2017 IPR009078 Ferritin-like superfamily CAK77_RS01990 da4e6d2243a172ae455de2d7a8e2ea16 274 Gene3D G3DSA:1.10.340.30 104 205 4.0E-10 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CAK77_RS01990 da4e6d2243a172ae455de2d7a8e2ea16 274 SUPERFAMILY SSF48150 93 251 1.13E-20 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CAK77_RS23450 71f11e143432e9058517c1eb938d1de0 146 Pfam PF12833 Helix-turn-helix domain 36 115 2.9E-22 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK77_RS23450 71f11e143432e9058517c1eb938d1de0 146 Gene3D G3DSA:1.10.10.60 13 68 2.7E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS23450 71f11e143432e9058517c1eb938d1de0 146 SUPERFAMILY SSF46689 66 117 1.25E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS23450 71f11e143432e9058517c1eb938d1de0 146 SMART SM00342 30 113 1.1E-31 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK77_RS23450 71f11e143432e9058517c1eb938d1de0 146 Gene3D G3DSA:1.10.10.60 69 116 1.4E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS23450 71f11e143432e9058517c1eb938d1de0 146 SUPERFAMILY SSF46689 14 64 6.37E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS18450 24976d36085c2b5c39b2e644fe0eb2b5 251 SUPERFAMILY SSF81301 9 61 4.16E-9 T 06-07-2017 CAK77_RS18450 24976d36085c2b5c39b2e644fe0eb2b5 251 Pfam PF01909 Nucleotidyltransferase domain 16 63 9.4E-7 T 06-07-2017 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 CAK77_RS18450 24976d36085c2b5c39b2e644fe0eb2b5 251 Gene3D G3DSA:3.30.460.10 10 102 1.5E-12 T 06-07-2017 CAK77_RS19315 8e6e9d4b1222f53885dc6fe6a409c5a4 726 Pfam PF00384 Molybdopterin oxidoreductase 60 486 2.0E-43 T 06-07-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS19315 8e6e9d4b1222f53885dc6fe6a409c5a4 726 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 5 53 3.1E-8 T 06-07-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS19315 8e6e9d4b1222f53885dc6fe6a409c5a4 726 Pfam PF01568 Molydopterin dinucleotide binding domain 599 706 3.4E-19 T 06-07-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CAK77_RS19315 8e6e9d4b1222f53885dc6fe6a409c5a4 726 Gene3D G3DSA:2.40.40.20 592 726 1.0E-25 T 06-07-2017 CAK77_RS19315 8e6e9d4b1222f53885dc6fe6a409c5a4 726 Gene3D G3DSA:2.20.25.90 3 61 1.2E-14 T 06-07-2017 CAK77_RS19315 8e6e9d4b1222f53885dc6fe6a409c5a4 726 Gene3D G3DSA:3.40.228.10 141 340 2.5E-45 T 06-07-2017 CAK77_RS19315 8e6e9d4b1222f53885dc6fe6a409c5a4 726 SUPERFAMILY SSF50692 591 726 1.83E-29 T 06-07-2017 IPR009010 Aspartate decarboxylase-like domain CAK77_RS19315 8e6e9d4b1222f53885dc6fe6a409c5a4 726 SUPERFAMILY SSF53706 4 495 2.22E-115 T 06-07-2017 CAK77_RS19315 8e6e9d4b1222f53885dc6fe6a409c5a4 726 SMART SM00926 3 57 1.3E-11 T 06-07-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS19315 8e6e9d4b1222f53885dc6fe6a409c5a4 726 Gene3D G3DSA:3.40.50.740 62 119 3.8E-47 T 06-07-2017 CAK77_RS19315 8e6e9d4b1222f53885dc6fe6a409c5a4 726 Gene3D G3DSA:3.40.50.740 370 489 3.8E-47 T 06-07-2017 CAK77_RS19395 342659827969fa216c312d8f7f271cde 292 SMART SM00046 3 128 4.8E-5 T 06-07-2017 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CAK77_RS19395 342659827969fa216c312d8f7f271cde 292 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 3 290 3.8E-38 T 06-07-2017 IPR005218 Diacylglycerol/lipid kinase CAK77_RS19395 342659827969fa216c312d8f7f271cde 292 SUPERFAMILY SSF111331 3 291 4.36E-68 T 06-07-2017 IPR016064 NAD kinase/diacylglycerol kinase-like domain CAK77_RS19395 342659827969fa216c312d8f7f271cde 292 Pfam PF00781 Diacylglycerol kinase catalytic domain 3 125 2.9E-25 T 06-07-2017 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CAK77_RS06450 fd64f0104e197761b5d8fc135ef72842 737 Pfam PF03176 MMPL family 50 377 7.9E-47 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 CAK77_RS06450 fd64f0104e197761b5d8fc135ef72842 737 Pfam PF03176 MMPL family 487 724 1.7E-37 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 CAK77_RS06450 fd64f0104e197761b5d8fc135ef72842 737 Gene3D G3DSA:1.20.1640.10 138 340 4.5E-30 T 06-07-2017 CAK77_RS06450 fd64f0104e197761b5d8fc135ef72842 737 Gene3D G3DSA:1.20.1640.10 503 725 4.8E-36 T 06-07-2017 CAK77_RS06450 fd64f0104e197761b5d8fc135ef72842 737 SUPERFAMILY SSF82866 128 337 1.09E-30 T 06-07-2017 CAK77_RS06450 fd64f0104e197761b5d8fc135ef72842 737 SUPERFAMILY SSF82866 502 721 4.97E-33 T 06-07-2017 CAK77_RS03310 0240f41ce3f17ddd2b5458061be07609 397 SUPERFAMILY SSF63867 324 396 5.63E-15 T 06-07-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 CAK77_RS03310 0240f41ce3f17ddd2b5458061be07609 397 Pfam PF03453 MoeA N-terminal region (domain I and II) 3 166 2.1E-34 T 06-07-2017 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 CAK77_RS03310 0240f41ce3f17ddd2b5458061be07609 397 Pfam PF03454 MoeA C-terminal region (domain IV) 328 395 3.0E-13 T 06-07-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 CAK77_RS03310 0240f41ce3f17ddd2b5458061be07609 397 Gene3D G3DSA:2.170.190.11 44 130 2.0E-33 T 06-07-2017 CAK77_RS03310 0240f41ce3f17ddd2b5458061be07609 397 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 176 310 8.2E-33 T 06-07-2017 IPR001453 MoaB/Mog domain CAK77_RS03310 0240f41ce3f17ddd2b5458061be07609 397 Gene3D G3DSA:2.40.340.10 327 394 2.2E-14 T 06-07-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 CAK77_RS03310 0240f41ce3f17ddd2b5458061be07609 397 SUPERFAMILY SSF53218 176 320 9.82E-39 T 06-07-2017 IPR001453 MoaB/Mog domain CAK77_RS03310 0240f41ce3f17ddd2b5458061be07609 397 SMART SM00852 179 315 2.4E-36 T 06-07-2017 IPR001453 MoaB/Mog domain CAK77_RS03310 0240f41ce3f17ddd2b5458061be07609 397 Gene3D G3DSA:3.90.105.10 131 161 3.7E-20 T 06-07-2017 CAK77_RS03310 0240f41ce3f17ddd2b5458061be07609 397 Pfam PF00994 Probable molybdopterin binding domain 180 313 1.1E-22 T 06-07-2017 IPR001453 MoaB/Mog domain CAK77_RS03310 0240f41ce3f17ddd2b5458061be07609 397 SUPERFAMILY SSF63882 1 175 1.57E-51 T 06-07-2017 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 CAK77_RS03310 0240f41ce3f17ddd2b5458061be07609 397 Gene3D G3DSA:3.40.980.10 162 326 1.0E-54 T 06-07-2017 IPR001453 MoaB/Mog domain CAK77_RS15820 266f2263820c8f1e5d20555e1d881489 288 SUPERFAMILY SSF53850 91 283 8.69E-16 T 06-07-2017 CAK77_RS15820 266f2263820c8f1e5d20555e1d881489 288 Pfam PF03466 LysR substrate binding domain 90 280 2.3E-16 T 06-07-2017 IPR005119 LysR, substrate-binding CAK77_RS15820 266f2263820c8f1e5d20555e1d881489 288 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 66 2.4E-17 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK77_RS15820 266f2263820c8f1e5d20555e1d881489 288 SUPERFAMILY SSF46785 5 109 1.19E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS15820 266f2263820c8f1e5d20555e1d881489 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 4.1E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK77_RS15820 266f2263820c8f1e5d20555e1d881489 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 4.1E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK77_RS15820 266f2263820c8f1e5d20555e1d881489 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 4.1E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK77_RS15820 266f2263820c8f1e5d20555e1d881489 288 Gene3D G3DSA:1.10.10.10 7 85 6.1E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS15820 266f2263820c8f1e5d20555e1d881489 288 Gene3D G3DSA:3.40.190.10 86 199 1.8E-11 T 06-07-2017 CAK77_RS03570 602bd509c3ef4064d112baa6f1f96d3e 297 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 10 286 9.4E-73 T 06-07-2017 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 CAK77_RS03570 602bd509c3ef4064d112baa6f1f96d3e 297 Gene3D G3DSA:3.30.200.20 4 106 1.1E-38 T 06-07-2017 CAK77_RS03570 602bd509c3ef4064d112baa6f1f96d3e 297 Gene3D G3DSA:3.30.470.20 107 237 2.2E-52 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAK77_RS03570 602bd509c3ef4064d112baa6f1f96d3e 297 SUPERFAMILY SSF56104 4 289 2.39E-97 T 06-07-2017 CAK77_RS03570 602bd509c3ef4064d112baa6f1f96d3e 297 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 8 286 25.551 T 06-07-2017 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CAK77_RS03570 602bd509c3ef4064d112baa6f1f96d3e 297 ProSitePatterns PS01057 SAICAR synthetase signature 1. 95 109 - T 06-07-2017 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CAK77_RS03570 602bd509c3ef4064d112baa6f1f96d3e 297 Pfam PF01259 SAICAR synthetase 10 258 4.3E-94 T 06-07-2017 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CAK77_RS03570 602bd509c3ef4064d112baa6f1f96d3e 297 ProSitePatterns PS01058 SAICAR synthetase signature 2. 194 202 - T 06-07-2017 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CAK77_RS05695 4bea8fee92d3c24a61b35e07767ce588 214 ProSitePatterns PS01081 TetR-type HTH domain signature. 39 69 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CAK77_RS05695 4bea8fee92d3c24a61b35e07767ce588 214 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 71 2.3E-19 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS05695 4bea8fee92d3c24a61b35e07767ce588 214 SUPERFAMILY SSF46689 13 92 1.55E-21 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS05695 4bea8fee92d3c24a61b35e07767ce588 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 40 2.6E-12 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS05695 4bea8fee92d3c24a61b35e07767ce588 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 48 71 2.6E-12 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS05695 4bea8fee92d3c24a61b35e07767ce588 214 SUPERFAMILY SSF48498 104 204 7.12E-7 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS05695 4bea8fee92d3c24a61b35e07767ce588 214 Gene3D G3DSA:1.10.357.10 10 203 8.4E-45 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS01270 59555a144e2a9680d737cd21f8a2d152 144 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 10 115 7.6E-10 T 06-07-2017 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CAK77_RS01270 59555a144e2a9680d737cd21f8a2d152 144 SUPERFAMILY SSF55961 3 139 1.29E-16 T 06-07-2017 CAK77_RS01270 59555a144e2a9680d737cd21f8a2d152 144 Gene3D G3DSA:3.30.530.20 3 113 3.5E-14 T 06-07-2017 IPR023393 START-like domain CAK77_RS13850 e869f6c274f5a29559512045225f80e8 191 Hamap MF_01219 Bifunctional protein PyrR [pyrR]. 7 185 35.926 T 06-07-2017 IPR023050 Bifunctional protein PyrR KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 CAK77_RS13850 e869f6c274f5a29559512045225f80e8 191 Pfam PF00156 Phosphoribosyl transferase domain 10 155 7.1E-20 T 06-07-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 CAK77_RS13850 e869f6c274f5a29559512045225f80e8 191 SUPERFAMILY SSF53271 10 179 2.1E-39 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like CAK77_RS13850 e869f6c274f5a29559512045225f80e8 191 Gene3D G3DSA:3.40.50.2020 9 178 4.9E-46 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like CAK77_RS19760 e502b9710608312f95219498f7ecce9c 276 Gene3D G3DSA:3.40.50.720 1 245 2.5E-45 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS19760 e502b9710608312f95219498f7ecce9c 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 89 100 6.3E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS19760 e502b9710608312f95219498f7ecce9c 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 6.3E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS19760 e502b9710608312f95219498f7ecce9c 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 184 6.3E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS19760 e502b9710608312f95219498f7ecce9c 276 SUPERFAMILY SSF51735 1 245 4.81E-46 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS19760 e502b9710608312f95219498f7ecce9c 276 Pfam PF00106 short chain dehydrogenase 7 198 5.2E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS16570 1f90415f654efacb3794d64d82490a68 387 SUPERFAMILY SSF50952 82 350 8.63E-13 T 06-07-2017 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 CAK77_RS16570 1f90415f654efacb3794d64d82490a68 387 Pfam PF07995 Glucose / Sorbosone dehydrogenase 97 238 6.2E-14 T 06-07-2017 IPR012938 Glucose/Sorbosone dehydrogenase GO:0005975|GO:0016901|GO:0048038 CAK77_RS16570 1f90415f654efacb3794d64d82490a68 387 Gene3D G3DSA:2.120.10.30 71 383 1.0E-30 T 06-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like CAK77_RS13250 9004d5424668456116152e0c9b20cb69 1058 SUPERFAMILY SSF50677 214 400 2.51E-45 T 06-07-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CAK77_RS13250 9004d5424668456116152e0c9b20cb69 1058 Hamap MF_02003 Isoleucine--tRNA ligase [ileS]. 12 1052 13.884 T 06-07-2017 IPR023586 Isoleucine-tRNA ligase, type 2 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CAK77_RS13250 9004d5424668456116152e0c9b20cb69 1058 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 17 860 9.1E-252 T 06-07-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CAK77_RS13250 9004d5424668456116152e0c9b20cb69 1058 Pfam PF08264 Anticodon-binding domain of tRNA 711 848 1.7E-23 T 06-07-2017 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CAK77_RS13250 9004d5424668456116152e0c9b20cb69 1058 Gene3D G3DSA:3.40.50.620 18 203 7.1E-147 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS13250 9004d5424668456116152e0c9b20cb69 1058 Gene3D G3DSA:3.40.50.620 424 660 7.1E-147 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS13250 9004d5424668456116152e0c9b20cb69 1058 SUPERFAMILY SSF52374 16 207 4.16E-131 T 06-07-2017 CAK77_RS13250 9004d5424668456116152e0c9b20cb69 1058 SUPERFAMILY SSF52374 421 662 4.16E-131 T 06-07-2017 CAK77_RS13250 9004d5424668456116152e0c9b20cb69 1058 Gene3D G3DSA:3.90.740.10 214 399 6.2E-55 T 06-07-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CAK77_RS13250 9004d5424668456116152e0c9b20cb69 1058 Gene3D G3DSA:1.10.730.10 671 842 4.4E-39 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK77_RS13250 9004d5424668456116152e0c9b20cb69 1058 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 57 68 - T 06-07-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK77_RS13250 9004d5424668456116152e0c9b20cb69 1058 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 548 561 8.7E-32 T 06-07-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CAK77_RS13250 9004d5424668456116152e0c9b20cb69 1058 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 241 264 8.7E-32 T 06-07-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CAK77_RS13250 9004d5424668456116152e0c9b20cb69 1058 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 588 597 8.7E-32 T 06-07-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CAK77_RS13250 9004d5424668456116152e0c9b20cb69 1058 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 419 434 8.7E-32 T 06-07-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CAK77_RS13250 9004d5424668456116152e0c9b20cb69 1058 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 50 61 8.7E-32 T 06-07-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CAK77_RS13250 9004d5424668456116152e0c9b20cb69 1058 SUPERFAMILY SSF47323 683 908 8.78E-45 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK77_RS13250 9004d5424668456116152e0c9b20cb69 1058 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 27 663 1.3E-183 T 06-07-2017 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK77_RS14980 8dabaeb2e0b1e355d0efdb3dc4008c12 491 PRINTS PR00046 Major sigma-70 factor signature 282 295 3.4E-29 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS14980 8dabaeb2e0b1e355d0efdb3dc4008c12 491 PRINTS PR00046 Major sigma-70 factor signature 466 477 3.4E-29 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS14980 8dabaeb2e0b1e355d0efdb3dc4008c12 491 PRINTS PR00046 Major sigma-70 factor signature 451 466 3.4E-29 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS14980 8dabaeb2e0b1e355d0efdb3dc4008c12 491 PRINTS PR00046 Major sigma-70 factor signature 430 442 3.4E-29 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS14980 8dabaeb2e0b1e355d0efdb3dc4008c12 491 PRINTS PR00046 Major sigma-70 factor signature 306 314 3.4E-29 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS14980 8dabaeb2e0b1e355d0efdb3dc4008c12 491 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 254 490 6.0E-114 T 06-07-2017 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 CAK77_RS14980 8dabaeb2e0b1e355d0efdb3dc4008c12 491 Pfam PF04545 Sigma-70, region 4 426 479 2.3E-18 T 06-07-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS14980 8dabaeb2e0b1e355d0efdb3dc4008c12 491 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 282 295 - T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS14980 8dabaeb2e0b1e355d0efdb3dc4008c12 491 SUPERFAMILY SSF88659 390 490 1.98E-26 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS14980 8dabaeb2e0b1e355d0efdb3dc4008c12 491 SUPERFAMILY SSF88659 331 404 1.8E-22 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS14980 8dabaeb2e0b1e355d0efdb3dc4008c12 491 SUPERFAMILY SSF88946 186 328 6.17E-54 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS14980 8dabaeb2e0b1e355d0efdb3dc4008c12 491 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 254 479 1.3E-35 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS14980 8dabaeb2e0b1e355d0efdb3dc4008c12 491 Gene3D G3DSA:1.10.10.10 331 382 2.4E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS14980 8dabaeb2e0b1e355d0efdb3dc4008c12 491 Pfam PF04542 Sigma-70 region 2 258 327 1.9E-22 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS14980 8dabaeb2e0b1e355d0efdb3dc4008c12 491 Gene3D G3DSA:1.10.10.10 421 491 1.7E-31 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS14980 8dabaeb2e0b1e355d0efdb3dc4008c12 491 Pfam PF04539 Sigma-70 region 3 337 412 1.7E-28 T 06-07-2017 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS14980 8dabaeb2e0b1e355d0efdb3dc4008c12 491 Pfam PF00140 Sigma-70 factor, region 1.2 189 222 4.3E-16 T 06-07-2017 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS14980 8dabaeb2e0b1e355d0efdb3dc4008c12 491 Gene3D G3DSA:1.10.601.10 167 327 2.2E-61 T 06-07-2017 CAK77_RS14980 8dabaeb2e0b1e355d0efdb3dc4008c12 491 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 451 477 - T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS14980 8dabaeb2e0b1e355d0efdb3dc4008c12 491 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 88 491 33.743 T 06-07-2017 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 CAK77_RS20940 a27769e4b970732a8983f3d69705e867 261 SUPERFAMILY SSF51735 7 257 2.63E-70 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS20940 a27769e4b970732a8983f3d69705e867 261 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 257 6.3E-52 T 06-07-2017 CAK77_RS20940 a27769e4b970732a8983f3d69705e867 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 2.9E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS20940 a27769e4b970732a8983f3d69705e867 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 2.9E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS20940 a27769e4b970732a8983f3d69705e867 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 2.9E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS20940 a27769e4b970732a8983f3d69705e867 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 5.9E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS20940 a27769e4b970732a8983f3d69705e867 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 5.9E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS20940 a27769e4b970732a8983f3d69705e867 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 5.9E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS20940 a27769e4b970732a8983f3d69705e867 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 5.9E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS20940 a27769e4b970732a8983f3d69705e867 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 5.9E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS20940 a27769e4b970732a8983f3d69705e867 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 5.9E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS20940 a27769e4b970732a8983f3d69705e867 261 Gene3D G3DSA:3.40.50.720 5 257 6.1E-71 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS15705 a7e46afcd1cfbb8bd93bdeada0ffa69f 204 SUPERFAMILY SSF52540 11 204 1.52E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS15705 a7e46afcd1cfbb8bd93bdeada0ffa69f 204 TIGRFAM TIGR00708 cobA: cob(I)yrinic acid a,c-diamide adenosyltransferase 18 204 1.4E-75 T 06-07-2017 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 CAK77_RS15705 a7e46afcd1cfbb8bd93bdeada0ffa69f 204 Pfam PF02572 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 24 204 2.9E-58 T 06-07-2017 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 CAK77_RS15705 a7e46afcd1cfbb8bd93bdeada0ffa69f 204 PIRSF PIRSF015617 1 204 1.2E-64 T 06-07-2017 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 CAK77_RS15705 a7e46afcd1cfbb8bd93bdeada0ffa69f 204 Gene3D G3DSA:3.40.50.300 10 204 5.4E-64 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS05075 527b92e37b7dbbd5caf76cf52c3bf1f4 498 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 171 343 6.4E-11 T 06-07-2017 IPR024516 Mammalian cell entry, C-terminal CAK77_RS05075 527b92e37b7dbbd5caf76cf52c3bf1f4 498 Pfam PF02470 MlaD protein 25 101 2.9E-8 T 06-07-2017 IPR003399 Mce/MlaD CAK77_RS23190 9436729650099bf9a8caf76a2c45fb0f 216 Pfam PF00156 Phosphoribosyl transferase domain 27 172 6.8E-19 T 06-07-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 CAK77_RS23190 9436729650099bf9a8caf76a2c45fb0f 216 SUPERFAMILY SSF53271 7 211 7.11E-49 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like CAK77_RS23190 9436729650099bf9a8caf76a2c45fb0f 216 Gene3D G3DSA:3.40.50.2020 3 70 1.0E-36 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like CAK77_RS23190 9436729650099bf9a8caf76a2c45fb0f 216 Gene3D G3DSA:3.40.50.2020 102 206 1.0E-36 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like CAK77_RS15245 58baced9d2df69e27b6b571114926594 385 Gene3D G3DSA:3.40.50.2000 214 364 5.9E-20 T 06-07-2017 CAK77_RS15245 58baced9d2df69e27b6b571114926594 385 Gene3D G3DSA:3.40.50.2000 2 213 7.2E-12 T 06-07-2017 CAK77_RS15245 58baced9d2df69e27b6b571114926594 385 SUPERFAMILY SSF53756 2 382 3.14E-60 T 06-07-2017 CAK77_RS00330 9db0476b14011932132e71473b6b452c 420 Pfam PF00069 Protein kinase domain 13 262 6.1E-48 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CAK77_RS00330 9db0476b14011932132e71473b6b452c 420 Gene3D G3DSA:1.10.510.10 103 296 2.0E-44 T 06-07-2017 CAK77_RS00330 9db0476b14011932132e71473b6b452c 420 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 137 149 - T 06-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CAK77_RS00330 9db0476b14011932132e71473b6b452c 420 SMART SM00220 13 272 7.1E-63 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CAK77_RS00330 9db0476b14011932132e71473b6b452c 420 SUPERFAMILY SSF56112 11 325 1.16E-76 T 06-07-2017 IPR011009 Protein kinase-like domain CAK77_RS00330 9db0476b14011932132e71473b6b452c 420 Gene3D G3DSA:3.30.200.20 3 97 1.1E-26 T 06-07-2017 CAK77_RS06990 ad1b1a1eb26525aecb3ebc9ce4c6f88d 490 SUPERFAMILY SSF103473 245 416 5.76E-66 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK77_RS06990 ad1b1a1eb26525aecb3ebc9ce4c6f88d 490 SUPERFAMILY SSF103473 6 200 5.76E-66 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK77_RS06990 ad1b1a1eb26525aecb3ebc9ce4c6f88d 490 SUPERFAMILY SSF103473 445 472 5.76E-66 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK77_RS06990 ad1b1a1eb26525aecb3ebc9ce4c6f88d 490 PRINTS PR01036 Tetracycline resistance protein TetB signature 9 33 8.6E-9 T 06-07-2017 CAK77_RS06990 ad1b1a1eb26525aecb3ebc9ce4c6f88d 490 PRINTS PR01036 Tetracycline resistance protein TetB signature 135 159 8.6E-9 T 06-07-2017 CAK77_RS06990 ad1b1a1eb26525aecb3ebc9ce4c6f88d 490 PRINTS PR01036 Tetracycline resistance protein TetB signature 199 217 8.6E-9 T 06-07-2017 CAK77_RS06990 ad1b1a1eb26525aecb3ebc9ce4c6f88d 490 PRINTS PR01036 Tetracycline resistance protein TetB signature 105 125 8.6E-9 T 06-07-2017 CAK77_RS06990 ad1b1a1eb26525aecb3ebc9ce4c6f88d 490 Gene3D G3DSA:1.20.1250.20 8 196 2.3E-37 T 06-07-2017 CAK77_RS06990 ad1b1a1eb26525aecb3ebc9ce4c6f88d 490 Gene3D G3DSA:1.20.1250.20 257 461 7.8E-21 T 06-07-2017 CAK77_RS06990 ad1b1a1eb26525aecb3ebc9ce4c6f88d 490 Pfam PF07690 Major Facilitator Superfamily 15 406 4.9E-57 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK77_RS06990 ad1b1a1eb26525aecb3ebc9ce4c6f88d 490 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 11 420 9.4E-86 T 06-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CAK77_RS08700 78bd17f725f7ccf7a245a03ba573059b 425 Pfam PF13286 Phosphohydrolase-associated domain 325 413 9.0E-16 T 06-07-2017 IPR026875 Phosphohydrolase-associated domain CAK77_RS08700 78bd17f725f7ccf7a245a03ba573059b 425 Gene3D G3DSA:1.10.3210.10 27 212 3.3E-62 T 06-07-2017 IPR006674 HD domain CAK77_RS08700 78bd17f725f7ccf7a245a03ba573059b 425 TIGRFAM TIGR01353 dGTP_triPase: putative dGTPase 34 406 2.5E-67 T 06-07-2017 IPR006261 Deoxyguanosinetriphosphate triphosphohydrolase GO:0000287|GO:0008832|GO:0046039 CAK77_RS08700 78bd17f725f7ccf7a245a03ba573059b 425 Pfam PF01966 HD domain 71 215 3.6E-17 T 06-07-2017 IPR006674 HD domain CAK77_RS08700 78bd17f725f7ccf7a245a03ba573059b 425 SMART SM00471 67 226 9.1E-12 T 06-07-2017 IPR003607 HD/PDEase domain CAK77_RS08700 78bd17f725f7ccf7a245a03ba573059b 425 Gene3D G3DSA:1.10.3410.10 213 344 1.1E-16 T 06-07-2017 IPR023293 Deoxyguanosinetriphosphate triphosphohydrolase, central domain CAK77_RS08700 78bd17f725f7ccf7a245a03ba573059b 425 Hamap MF_01212 Deoxyguanosinetriphosphate triphosphohydrolase-like protein. 1 418 30.792 T 06-07-2017 IPR023023 Deoxyguanosinetriphosphate triphosphohydrolase, type 2 CAK77_RS08700 78bd17f725f7ccf7a245a03ba573059b 425 SUPERFAMILY SSF109604 34 235 5.45E-55 T 06-07-2017 CAK77_RS21050 513065795e132e6b512a04c99e0eb29d 297 Pfam PF08281 Sigma-70, region 4 113 159 8.0E-12 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS21050 513065795e132e6b512a04c99e0eb29d 297 SUPERFAMILY SSF88946 5 71 5.49E-6 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS21050 513065795e132e6b512a04c99e0eb29d 297 Gene3D G3DSA:1.10.10.10 107 163 5.4E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS21050 513065795e132e6b512a04c99e0eb29d 297 Gene3D G3DSA:1.10.1740.10 11 82 2.4E-5 T 06-07-2017 CAK77_RS21050 513065795e132e6b512a04c99e0eb29d 297 Pfam PF04542 Sigma-70 region 2 14 73 4.0E-6 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS21050 513065795e132e6b512a04c99e0eb29d 297 Gene3D G3DSA:3.10.450.50 171 288 7.5E-17 T 06-07-2017 IPR032710 NTF2-like domain CAK77_RS21050 513065795e132e6b512a04c99e0eb29d 297 SUPERFAMILY SSF88659 84 163 1.87E-13 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS21050 513065795e132e6b512a04c99e0eb29d 297 SUPERFAMILY SSF54427 176 290 6.31E-17 T 06-07-2017 IPR032710 NTF2-like domain CAK77_RS21050 513065795e132e6b512a04c99e0eb29d 297 Pfam PF12680 SnoaL-like domain 180 276 3.7E-6 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain CAK77_RS21050 513065795e132e6b512a04c99e0eb29d 297 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 11 160 1.2E-14 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS18325 fbdf51e7cfc7e0db701fc86002b78bc0 563 Pfam PF14559 Tetratricopeptide repeat 3 67 1.3E-8 T 06-07-2017 CAK77_RS18325 fbdf51e7cfc7e0db701fc86002b78bc0 563 Gene3D G3DSA:1.25.40.10 2 208 2.4E-24 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK77_RS18325 fbdf51e7cfc7e0db701fc86002b78bc0 563 SUPERFAMILY SSF48452 2 207 8.85E-19 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK77_RS21205 1a2b0b82a7418d9140ec1c30acf41448 243 SMART SM00849 18 225 6.5E-22 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK77_RS21205 1a2b0b82a7418d9140ec1c30acf41448 243 SUPERFAMILY SSF56281 2 231 3.01E-38 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK77_RS21205 1a2b0b82a7418d9140ec1c30acf41448 243 Gene3D G3DSA:3.60.15.10 2 231 2.2E-36 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK77_RS21205 1a2b0b82a7418d9140ec1c30acf41448 243 Pfam PF00753 Metallo-beta-lactamase superfamily 18 225 1.6E-30 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK77_RS05270 f28633c950633e6384df420ebfcdd931 268 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 33 211 1.0E-37 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal CAK77_RS05270 f28633c950633e6384df420ebfcdd931 268 SUPERFAMILY SSF53639 25 237 4.12E-64 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal CAK77_RS05270 f28633c950633e6384df420ebfcdd931 268 Gene3D G3DSA:3.40.225.10 28 238 2.2E-52 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal CAK77_RS05270 f28633c950633e6384df420ebfcdd931 268 SMART SM01007 33 211 6.6E-46 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal CAK77_RS12105 05692e801a25a948b88558a6f596a1dc 182 Pfam PF08819 Domain of unknown function (DUF1802) 4 174 1.5E-58 T 06-07-2017 IPR014923 Protein of unknown function DUF1802 CAK77_RS12105 05692e801a25a948b88558a6f596a1dc 182 PIRSF PIRSF018957 1 181 1.6E-70 T 06-07-2017 IPR008307 Uncharacterised conserved protein UCP018957 CAK77_RS15290 987ff69099fe282efffe531b7260b35c 199 Pfam PF01066 CDP-alcohol phosphatidyltransferase 22 92 2.4E-14 T 06-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CAK77_RS15290 987ff69099fe282efffe531b7260b35c 199 PIRSF PIRSF000847 19 198 6.3E-44 T 06-07-2017 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668 CAK77_RS15290 987ff69099fe282efffe531b7260b35c 199 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 22 192 2.0E-37 T 06-07-2017 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668 CAK77_RS15290 987ff69099fe282efffe531b7260b35c 199 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 70 92 - T 06-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CAK77_RS15100 8cafd2c45e234bfe6cd3c3350eb51de5 330 Gene3D G3DSA:1.10.287.100 241 282 1.6E-20 T 06-07-2017 IPR013028 Transcription factor IIA, alpha subunit, N-terminal GO:0006367 CAK77_RS15100 8cafd2c45e234bfe6cd3c3350eb51de5 330 SUPERFAMILY SSF159659 19 284 5.49E-89 T 06-07-2017 CAK77_RS15100 8cafd2c45e234bfe6cd3c3350eb51de5 330 PIRSF PIRSF028754 20 322 6.6E-119 T 06-07-2017 IPR008492 Protein of unknown function DUF774 CAK77_RS15100 8cafd2c45e234bfe6cd3c3350eb51de5 330 Pfam PF09754 PAC2 family 43 259 5.5E-47 T 06-07-2017 IPR019151 Proteasome assembly chaperone 2 CAK77_RS12280 17a7fbbdd3934de3940f72e878049c0a 202 SUPERFAMILY SSF109755 1 196 2.2E-36 T 06-07-2017 CAK77_RS12280 17a7fbbdd3934de3940f72e878049c0a 202 Pfam PF01895 PhoU domain 1 84 9.5E-6 T 06-07-2017 IPR026022 PhoU domain CAK77_RS12280 17a7fbbdd3934de3940f72e878049c0a 202 Pfam PF01895 PhoU domain 105 185 8.6E-8 T 06-07-2017 IPR026022 PhoU domain CAK77_RS12280 17a7fbbdd3934de3940f72e878049c0a 202 Gene3D G3DSA:1.20.58.220 1 87 2.4E-10 T 06-07-2017 CAK77_RS12280 17a7fbbdd3934de3940f72e878049c0a 202 Gene3D G3DSA:1.20.58.220 99 195 4.7E-13 T 06-07-2017 CAK77_RS17810 70c3deb277c316dc7f0e969bcfd407ed 440 Pfam PF00392 Bacterial regulatory proteins, gntR family 8 68 1.7E-11 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK77_RS17810 70c3deb277c316dc7f0e969bcfd407ed 440 SUPERFAMILY SSF46785 4 72 9.44E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS17810 70c3deb277c316dc7f0e969bcfd407ed 440 SUPERFAMILY SSF53383 63 437 1.79E-68 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK77_RS17810 70c3deb277c316dc7f0e969bcfd407ed 440 SMART SM00345 9 68 1.4E-12 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK77_RS17810 70c3deb277c316dc7f0e969bcfd407ed 440 Pfam PF00155 Aminotransferase class I and II 91 434 1.2E-25 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAK77_RS17810 70c3deb277c316dc7f0e969bcfd407ed 440 Gene3D G3DSA:3.40.640.10 117 336 4.2E-54 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK77_RS17810 70c3deb277c316dc7f0e969bcfd407ed 440 Gene3D G3DSA:1.10.10.10 7 72 4.4E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS04990 8ce9a991c3b38254b2f5fe8cfd2a0b4c 113 Gene3D G3DSA:3.40.30.10 3 113 4.1E-45 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK77_RS04990 8ce9a991c3b38254b2f5fe8cfd2a0b4c 113 SUPERFAMILY SSF52833 3 113 5.82E-30 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK77_RS04990 8ce9a991c3b38254b2f5fe8cfd2a0b4c 113 Pfam PF03960 ArsC family 6 112 3.8E-12 T 06-07-2017 IPR006660 Arsenate reductase-like CAK77_RS04990 8ce9a991c3b38254b2f5fe8cfd2a0b4c 113 TIGRFAM TIGR00014 arsC: arsenate reductase (glutaredoxin) 4 113 6.6E-43 T 06-07-2017 IPR006659 Arsenate reductase GO:0008794|GO:0055114 MetaCyc: PWY-4202|MetaCyc: PWY-4621 CAK77_RS04635 a2f045594a6f6c627b5315d1071c8e99 259 SUPERFAMILY SSF52317 7 195 1.19E-45 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAK77_RS04635 a2f045594a6f6c627b5315d1071c8e99 259 Gene3D G3DSA:3.40.50.880 7 210 1.7E-64 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAK77_RS04635 a2f045594a6f6c627b5315d1071c8e99 259 Pfam PF01965 DJ-1/PfpI family 7 167 9.8E-23 T 06-07-2017 IPR002818 DJ-1/PfpI CAK77_RS23520 258ba7e6c9d01bd8abf3fd26132e96f0 254 SUPERFAMILY SSF46955 13 113 1.68E-21 T 06-07-2017 IPR009061 Putative DNA-binding domain CAK77_RS23520 258ba7e6c9d01bd8abf3fd26132e96f0 254 Gene3D G3DSA:1.10.1660.10 13 114 2.4E-23 T 06-07-2017 CAK77_RS23520 258ba7e6c9d01bd8abf3fd26132e96f0 254 SMART SM00422 12 81 8.9E-12 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAK77_RS23520 258ba7e6c9d01bd8abf3fd26132e96f0 254 Pfam PF13411 MerR HTH family regulatory protein 13 77 1.7E-11 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAK77_RS17555 63fa752247e0d562f57453b0f1827832 474 Gene3D G3DSA:3.90.1200.10 192 237 6.4E-5 T 06-07-2017 CAK77_RS17555 63fa752247e0d562f57453b0f1827832 474 SUPERFAMILY SSF56112 120 183 1.43E-25 T 06-07-2017 IPR011009 Protein kinase-like domain CAK77_RS17555 63fa752247e0d562f57453b0f1827832 474 SUPERFAMILY SSF56112 384 431 1.43E-25 T 06-07-2017 IPR011009 Protein kinase-like domain CAK77_RS17555 63fa752247e0d562f57453b0f1827832 474 SUPERFAMILY SSF56112 215 329 1.43E-25 T 06-07-2017 IPR011009 Protein kinase-like domain CAK77_RS17555 63fa752247e0d562f57453b0f1827832 474 Gene3D G3DSA:3.30.200.20 142 191 9.1E-4 T 06-07-2017 CAK77_RS17555 63fa752247e0d562f57453b0f1827832 474 Pfam PF03109 ABC1 family 138 252 1.0E-34 T 06-07-2017 IPR004147 UbiB domain CAK77_RS17555 63fa752247e0d562f57453b0f1827832 474 Gene3D G3DSA:1.10.510.10 257 331 6.0E-5 T 06-07-2017 CAK77_RS19050 6be9bba4e047835b965257b157050f99 278 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 273 48.167 T 06-07-2017 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS19050 6be9bba4e047835b965257b157050f99 278 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 126 251 2.8E-54 T 06-07-2017 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 CAK77_RS19050 6be9bba4e047835b965257b157050f99 278 SUPERFAMILY SSF50249 2 126 1.71E-49 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS19050 6be9bba4e047835b965257b157050f99 278 SMART SM01382 125 253 5.8E-88 T 06-07-2017 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 CAK77_RS19050 6be9bba4e047835b965257b157050f99 278 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 119 8.2E-33 T 06-07-2017 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS19050 6be9bba4e047835b965257b157050f99 278 PIRSF PIRSF002158 3 275 4.4E-93 T 06-07-2017 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS19050 6be9bba4e047835b965257b157050f99 278 Gene3D G3DSA:2.40.50.140 1 115 5.0E-50 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS19050 6be9bba4e047835b965257b157050f99 278 Gene3D G3DSA:4.10.950.10 197 273 4.6E-32 T 06-07-2017 IPR014726 Ribosomal protein L2, domain 3 CAK77_RS19050 6be9bba4e047835b965257b157050f99 278 ProSitePatterns PS00467 Ribosomal protein L2 signature. 219 230 - T 06-07-2017 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK77_RS19050 6be9bba4e047835b965257b157050f99 278 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 273 9.8E-129 T 06-07-2017 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS19050 6be9bba4e047835b965257b157050f99 278 Gene3D G3DSA:2.30.30.30 120 196 2.0E-29 T 06-07-2017 IPR014722 Ribosomal protein L2 domain 2 CAK77_RS19050 6be9bba4e047835b965257b157050f99 278 SUPERFAMILY SSF50104 127 271 3.37E-55 T 06-07-2017 IPR008991 Translation protein SH3-like domain CAK77_RS19050 6be9bba4e047835b965257b157050f99 278 SMART SM01383 42 119 1.5E-39 T 06-07-2017 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS18290 ccd68eba0f9125a804da2276c1840300 132 SUPERFAMILY SSF53927 3 128 6.91E-40 T 06-07-2017 IPR016193 Cytidine deaminase-like GO:0003824 CAK77_RS18290 ccd68eba0f9125a804da2276c1840300 132 TIGRFAM TIGR01354 cyt_deam_tetra: cytidine deaminase 8 127 1.4E-34 T 06-07-2017 IPR006262 Cytidine deaminase, homotetrameric GO:0004126|GO:0008270|GO:0009972 KEGG: 00240+3.5.4.5|KEGG: 00983+3.5.4.5|MetaCyc: PWY-6556|MetaCyc: PWY-7181|MetaCyc: PWY-7193|MetaCyc: PWY-7199|Reactome: R-HSA-73614 CAK77_RS18290 ccd68eba0f9125a804da2276c1840300 132 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 8 99 1.1E-10 T 06-07-2017 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 CAK77_RS18290 ccd68eba0f9125a804da2276c1840300 132 Gene3D G3DSA:3.40.140.10 4 128 9.7E-44 T 06-07-2017 CAK77_RS16060 5c8229681f3e273dc1089649751ea5ed 80 Hamap MF_00088 UPF0109 protein . 5 76 20.876 T 06-07-2017 IPR020627 Uncharacterised protein family UPF0109 CAK77_RS16060 5c8229681f3e273dc1089649751ea5ed 80 Gene3D G3DSA:3.30.300.120 7 65 1.5E-7 T 06-07-2017 CAK77_RS16060 5c8229681f3e273dc1089649751ea5ed 80 Pfam PF13083 KH domain 7 67 1.8E-20 T 06-07-2017 CAK77_RS16060 5c8229681f3e273dc1089649751ea5ed 80 SUPERFAMILY SSF54814 19 63 3.6E-8 T 06-07-2017 IPR009019 K homology domain, prokaryotic type GO:0003723 CAK77_RS19755 3d78b1319f823ab29c49228889264b05 310 Gene3D G3DSA:1.10.12.10 249 298 1.4E-27 T 06-07-2017 IPR014748 Crontonase, C-terminal CAK77_RS19755 3d78b1319f823ab29c49228889264b05 310 Pfam PF00378 Enoyl-CoA hydratase/isomerase 41 304 2.7E-50 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAK77_RS19755 3d78b1319f823ab29c49228889264b05 310 Gene3D G3DSA:3.90.226.10 32 246 9.9E-67 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS19755 3d78b1319f823ab29c49228889264b05 310 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 147 167 - T 06-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CAK77_RS19755 3d78b1319f823ab29c49228889264b05 310 SUPERFAMILY SSF52096 33 308 7.3E-76 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS19755 3d78b1319f823ab29c49228889264b05 310 TIGRFAM TIGR01929 menB: naphthoate synthase 26 304 1.6E-128 T 06-07-2017 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 CAK77_RS19755 3d78b1319f823ab29c49228889264b05 310 Hamap MF_01934 1,4-dihydroxy-2-naphthoyl-CoA synthase [menB]. 17 309 52.271 T 06-07-2017 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 CAK77_RS09975 d9cfb5188bf890292e10d47f7820dd9d 347 Gene3D G3DSA:3.20.20.30 12 338 5.8E-62 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS09975 d9cfb5188bf890292e10d47f7820dd9d 347 SUPERFAMILY SSF51679 11 332 8.64E-60 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS09975 d9cfb5188bf890292e10d47f7820dd9d 347 Pfam PF00296 Luciferase-like monooxygenase 11 304 2.6E-61 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS00005 6f49fc6daade19bbc080ee1b0a3641dc 491 ProSitePatterns PS01008 DnaA protein signature. 446 464 - T 06-07-2017 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 CAK77_RS00005 6f49fc6daade19bbc080ee1b0a3641dc 491 SMART SM00382 184 312 1.4E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS00005 6f49fc6daade19bbc080ee1b0a3641dc 491 Gene3D G3DSA:1.10.1750.10 387 487 1.4E-33 T 06-07-2017 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 CAK77_RS00005 6f49fc6daade19bbc080ee1b0a3641dc 491 SUPERFAMILY SSF52540 152 363 5.7E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS00005 6f49fc6daade19bbc080ee1b0a3641dc 491 SUPERFAMILY SSF48295 383 487 9.94E-32 T 06-07-2017 IPR010921 Trp repressor/replication initiator GO:0043565 CAK77_RS00005 6f49fc6daade19bbc080ee1b0a3641dc 491 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 399 464 1.0E-26 T 06-07-2017 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 CAK77_RS00005 6f49fc6daade19bbc080ee1b0a3641dc 491 Pfam PF00308 Bacterial dnaA protein 152 369 3.2E-101 T 06-07-2017 IPR013317 Chromosomal replication initiator protein DnaA CAK77_RS00005 6f49fc6daade19bbc080ee1b0a3641dc 491 SMART SM00760 396 464 6.2E-33 T 06-07-2017 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 CAK77_RS00005 6f49fc6daade19bbc080ee1b0a3641dc 491 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 38 485 2.9E-148 T 06-07-2017 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 CAK77_RS00005 6f49fc6daade19bbc080ee1b0a3641dc 491 Gene3D G3DSA:3.40.50.300 146 316 1.8E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS00005 6f49fc6daade19bbc080ee1b0a3641dc 491 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 10 486 32.199 T 06-07-2017 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 CAK77_RS00005 6f49fc6daade19bbc080ee1b0a3641dc 491 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 217 231 3.3E-48 T 06-07-2017 IPR020591 Chromosomal replication control, initiator DnaA-like CAK77_RS00005 6f49fc6daade19bbc080ee1b0a3641dc 491 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 283 310 3.3E-48 T 06-07-2017 IPR020591 Chromosomal replication control, initiator DnaA-like CAK77_RS00005 6f49fc6daade19bbc080ee1b0a3641dc 491 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 445 464 3.3E-48 T 06-07-2017 IPR020591 Chromosomal replication control, initiator DnaA-like CAK77_RS00005 6f49fc6daade19bbc080ee1b0a3641dc 491 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 185 205 3.3E-48 T 06-07-2017 IPR020591 Chromosomal replication control, initiator DnaA-like CAK77_RS00005 6f49fc6daade19bbc080ee1b0a3641dc 491 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 249 263 3.3E-48 T 06-07-2017 IPR020591 Chromosomal replication control, initiator DnaA-like CAK77_RS00005 6f49fc6daade19bbc080ee1b0a3641dc 491 Gene3D G3DSA:1.10.8.60 318 386 2.9E-29 T 06-07-2017 CAK77_RS01050 cb5031146123fcda1e17e625d0cfe996 325 Gene3D G3DSA:3.40.50.1820 43 322 8.7E-106 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS01050 cb5031146123fcda1e17e625d0cfe996 325 Pfam PF00756 Putative esterase 55 317 4.8E-53 T 06-07-2017 IPR000801 Putative esterase Reactome: R-HSA-156590 CAK77_RS01050 cb5031146123fcda1e17e625d0cfe996 325 SUPERFAMILY SSF53474 41 322 1.69E-30 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS01850 a39bfd70e5ca71aa8d7ae7ef9268a31c 146 SUPERFAMILY SSF54427 3 143 2.62E-29 T 06-07-2017 IPR032710 NTF2-like domain CAK77_RS01850 a39bfd70e5ca71aa8d7ae7ef9268a31c 146 Gene3D G3DSA:3.10.450.50 4 141 1.0E-31 T 06-07-2017 IPR032710 NTF2-like domain CAK77_RS01850 a39bfd70e5ca71aa8d7ae7ef9268a31c 146 Pfam PF13577 SnoaL-like domain 3 131 3.3E-24 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain CAK77_RS20725 e5f16b04d4e196f68feb5a9a2cf8712b 288 TIGRFAM TIGR03707 PPK2_P_aer: polyphosphate kinase 2 44 270 9.1E-117 T 06-07-2017 IPR022486 Polyphosphate kinase 2, PA0141 GO:0006793|GO:0008976 CAK77_RS20725 e5f16b04d4e196f68feb5a9a2cf8712b 288 PIRSF PIRSF028756 15 285 9.6E-119 T 06-07-2017 IPR016898 Polyphosphate kinase 2 CAK77_RS20725 e5f16b04d4e196f68feb5a9a2cf8712b 288 SUPERFAMILY SSF52540 76 263 6.33E-30 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS20725 e5f16b04d4e196f68feb5a9a2cf8712b 288 Gene3D G3DSA:3.40.50.300 37 283 4.0E-106 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS20725 e5f16b04d4e196f68feb5a9a2cf8712b 288 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 45 270 1.5E-103 T 06-07-2017 IPR022488 Polyphosphate kinase-2-related CAK77_RS22225 95fd312b632cf68fe32443e4a083bd1d 428 SUPERFAMILY SSF48264 44 427 1.83E-75 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS22225 95fd312b632cf68fe32443e4a083bd1d 428 Gene3D G3DSA:1.10.630.10 42 427 7.7E-97 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS22225 95fd312b632cf68fe32443e4a083bd1d 428 Pfam PF00067 Cytochrome P450 303 400 3.2E-16 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS22225 95fd312b632cf68fe32443e4a083bd1d 428 PRINTS PR00359 B-class P450 signature 370 379 5.2E-40 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS22225 95fd312b632cf68fe32443e4a083bd1d 428 PRINTS PR00359 B-class P450 signature 320 347 5.2E-40 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS22225 95fd312b632cf68fe32443e4a083bd1d 428 PRINTS PR00359 B-class P450 signature 119 130 5.2E-40 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS22225 95fd312b632cf68fe32443e4a083bd1d 428 PRINTS PR00359 B-class P450 signature 348 363 5.2E-40 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS22225 95fd312b632cf68fe32443e4a083bd1d 428 PRINTS PR00359 B-class P450 signature 182 197 5.2E-40 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS22225 95fd312b632cf68fe32443e4a083bd1d 428 PRINTS PR00359 B-class P450 signature 226 248 5.2E-40 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS22225 95fd312b632cf68fe32443e4a083bd1d 428 PRINTS PR00359 B-class P450 signature 303 314 5.2E-40 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS22225 95fd312b632cf68fe32443e4a083bd1d 428 PRINTS PR00359 B-class P450 signature 165 181 5.2E-40 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS22225 95fd312b632cf68fe32443e4a083bd1d 428 PRINTS PR00359 B-class P450 signature 379 390 5.2E-40 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS05495 cbaa9296d1bd0baafb3f54e74699b7ee 251 Gene3D G3DSA:1.10.10.60 208 251 2.5E-8 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS05495 cbaa9296d1bd0baafb3f54e74699b7ee 251 Gene3D G3DSA:1.10.10.60 161 207 3.5E-7 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS05495 cbaa9296d1bd0baafb3f54e74699b7ee 251 Gene3D G3DSA:2.60.120.10 21 76 3.5E-8 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK77_RS05495 cbaa9296d1bd0baafb3f54e74699b7ee 251 SUPERFAMILY SSF51182 21 179 4.69E-13 T 06-07-2017 IPR011051 RmlC-like cupin domain CAK77_RS05495 cbaa9296d1bd0baafb3f54e74699b7ee 251 Pfam PF12833 Helix-turn-helix domain 176 251 5.3E-17 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK77_RS05495 cbaa9296d1bd0baafb3f54e74699b7ee 251 SUPERFAMILY SSF46689 207 251 6.72E-6 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS05495 cbaa9296d1bd0baafb3f54e74699b7ee 251 SMART SM00342 170 251 2.3E-17 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK77_RS23205 b0ebf6db84ef216ae55a27fddc786fe2 205 Pfam PF07336 Putative stress-induced transcription regulator 16 157 4.7E-13 T 06-07-2017 IPR010852 Putative stress-induced transcription regulator CAK77_RS23205 b0ebf6db84ef216ae55a27fddc786fe2 205 Pfam PF11706 CGNR zinc finger 162 201 4.3E-11 T 06-07-2017 IPR021005 Zinc finger, CGNR CAK77_RS23205 b0ebf6db84ef216ae55a27fddc786fe2 205 Gene3D G3DSA:1.10.3300.10 12 202 2.2E-27 T 06-07-2017 IPR023286 ABATE domain CAK77_RS23205 b0ebf6db84ef216ae55a27fddc786fe2 205 SUPERFAMILY SSF160904 11 200 1.19E-28 T 06-07-2017 CAK77_RS06010 d4ca6bb35c4b3971d6392ec2f1ead86e 390 PIRSF PIRSF001434 2 390 1.3E-139 T 06-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CAK77_RS06010 d4ca6bb35c4b3971d6392ec2f1ead86e 390 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 18 389 3.5E-142 T 06-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CAK77_RS06010 d4ca6bb35c4b3971d6392ec2f1ead86e 390 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 202 216 - T 06-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CAK77_RS06010 d4ca6bb35c4b3971d6392ec2f1ead86e 390 Gene3D G3DSA:3.90.1150.10 259 390 6.5E-48 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK77_RS06010 d4ca6bb35c4b3971d6392ec2f1ead86e 390 SUPERFAMILY SSF53383 18 390 2.36E-116 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK77_RS06010 d4ca6bb35c4b3971d6392ec2f1ead86e 390 Gene3D G3DSA:3.40.640.10 15 258 1.1E-92 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK77_RS18155 c7e7eed8d923888669b6022fa9d74b88 196 SUPERFAMILY SSF52218 9 181 6.01E-40 T 06-07-2017 IPR029039 Flavoprotein-like domain CAK77_RS18155 c7e7eed8d923888669b6022fa9d74b88 196 Pfam PF03358 NADPH-dependent FMN reductase 9 151 2.5E-37 T 06-07-2017 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CAK77_RS18155 c7e7eed8d923888669b6022fa9d74b88 196 Gene3D G3DSA:3.40.50.360 9 187 1.8E-49 T 06-07-2017 IPR029039 Flavoprotein-like domain CAK77_RS02010 92ee96496d54b1ffbc9e0aa1fc83fdda 1077 SUPERFAMILY SSF52540 315 738 1.16E-70 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS02010 92ee96496d54b1ffbc9e0aa1fc83fdda 1077 PIRSF PIRSF000980 2 1068 6.5E-301 T 06-07-2017 IPR006697 RecBCD enzyme subunit RecC GO:0008854|GO:0009338 CAK77_RS02010 92ee96496d54b1ffbc9e0aa1fc83fdda 1077 Pfam PF04257 Exodeoxyribonuclease V, gamma subunit 3 731 4.1E-194 T 06-07-2017 CAK77_RS02010 92ee96496d54b1ffbc9e0aa1fc83fdda 1077 SUPERFAMILY SSF52980 764 1074 1.29E-64 T 06-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CAK77_RS02010 92ee96496d54b1ffbc9e0aa1fc83fdda 1077 SUPERFAMILY SSF52540 3 306 2.12E-77 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS02010 92ee96496d54b1ffbc9e0aa1fc83fdda 1077 Hamap MF_01486 RecBCD enzyme subunit RecC [recC]. 2 1077 15.94 T 06-07-2017 IPR006697 RecBCD enzyme subunit RecC GO:0008854|GO:0009338 CAK77_RS02010 92ee96496d54b1ffbc9e0aa1fc83fdda 1077 TIGRFAM TIGR01450 recC: exodeoxyribonuclease V, gamma subunit 3 1018 1.3E-293 T 06-07-2017 IPR006697 RecBCD enzyme subunit RecC GO:0008854|GO:0009338 CAK77_RS02010 92ee96496d54b1ffbc9e0aa1fc83fdda 1077 Gene3D G3DSA:1.10.10.160 81 179 1.1E-17 T 06-07-2017 IPR013986 DExx box DNA helicase domain CAK77_RS20370 a0d1409fbe537c0658b2882c2be07c14 363 Gene3D G3DSA:3.30.43.10 24 78 4.4E-8 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CAK77_RS20370 a0d1409fbe537c0658b2882c2be07c14 363 SUPERFAMILY SSF56194 221 361 2.22E-27 T 06-07-2017 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK77_RS20370 a0d1409fbe537c0658b2882c2be07c14 363 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 363 67.713 T 06-07-2017 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK77_RS20370 a0d1409fbe537c0658b2882c2be07c14 363 Gene3D G3DSA:3.90.78.10 251 362 1.3E-37 T 06-07-2017 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK77_RS20370 a0d1409fbe537c0658b2882c2be07c14 363 SUPERFAMILY SSF56176 24 192 4.85E-29 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAK77_RS20370 a0d1409fbe537c0658b2882c2be07c14 363 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 223 359 5.8E-33 T 06-07-2017 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK77_RS20370 a0d1409fbe537c0658b2882c2be07c14 363 Pfam PF01565 FAD binding domain 38 162 2.2E-15 T 06-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CAK77_RS20370 a0d1409fbe537c0658b2882c2be07c14 363 Gene3D G3DSA:3.30.465.10 89 200 5.9E-46 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAK77_RS20370 a0d1409fbe537c0658b2882c2be07c14 363 Gene3D G3DSA:3.30.465.10 234 250 5.9E-46 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAK77_RS04925 cf57a20419e6dec7459554bd86c91a32 205 ProSitePatterns PS00893 Nudix box signature. 102 123 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CAK77_RS04925 cf57a20419e6dec7459554bd86c91a32 205 Pfam PF00293 NUDIX domain 68 178 1.2E-17 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 CAK77_RS04925 cf57a20419e6dec7459554bd86c91a32 205 SUPERFAMILY SSF55811 31 199 4.47E-32 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAK77_RS04925 cf57a20419e6dec7459554bd86c91a32 205 PRINTS PR00502 NUDIX hydrolase family signature 111 126 4.5E-5 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CAK77_RS04925 cf57a20419e6dec7459554bd86c91a32 205 PRINTS PR00502 NUDIX hydrolase family signature 97 111 4.5E-5 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CAK77_RS04925 cf57a20419e6dec7459554bd86c91a32 205 Gene3D G3DSA:3.90.79.10 30 200 3.8E-32 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAK77_RS05005 f1654b4fb9fa564f0ffbcef9aeacb90e 308 SUPERFAMILY SSF51679 23 306 6.18E-38 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS05005 f1654b4fb9fa564f0ffbcef9aeacb90e 308 Pfam PF00296 Luciferase-like monooxygenase 24 282 4.4E-20 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS05005 f1654b4fb9fa564f0ffbcef9aeacb90e 308 Gene3D G3DSA:3.20.20.30 34 306 2.6E-31 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS19310 80006129970ef71d4b0e5501e92145e5 1171 Gene3D G3DSA:2.30.150.10 513 578 1.5E-29 T 06-07-2017 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK77_RS19310 80006129970ef71d4b0e5501e92145e5 1171 Gene3D G3DSA:3.90.1100.10 581 635 1.2E-145 T 06-07-2017 CAK77_RS19310 80006129970ef71d4b0e5501e92145e5 1171 Gene3D G3DSA:3.90.1100.10 41 175 1.2E-145 T 06-07-2017 CAK77_RS19310 80006129970ef71d4b0e5501e92145e5 1171 Gene3D G3DSA:3.90.1100.10 364 512 1.2E-145 T 06-07-2017 CAK77_RS19310 80006129970ef71d4b0e5501e92145e5 1171 Gene3D G3DSA:2.40.270.10 708 735 2.3E-75 T 06-07-2017 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK77_RS19310 80006129970ef71d4b0e5501e92145e5 1171 Gene3D G3DSA:2.40.270.10 875 1033 2.3E-75 T 06-07-2017 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK77_RS19310 80006129970ef71d4b0e5501e92145e5 1171 SUPERFAMILY SSF64484 32 1142 0.0 T 06-07-2017 CAK77_RS19310 80006129970ef71d4b0e5501e92145e5 1171 Pfam PF04563 RNA polymerase beta subunit 99 419 3.5E-21 T 06-07-2017 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK77_RS19310 80006129970ef71d4b0e5501e92145e5 1171 Gene3D G3DSA:2.40.50.100 637 707 8.0E-29 T 06-07-2017 CAK77_RS19310 80006129970ef71d4b0e5501e92145e5 1171 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 240 852 0.0 T 06-07-2017 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK77_RS19310 80006129970ef71d4b0e5501e92145e5 1171 Pfam PF04560 RNA polymerase Rpb2, domain 7 1057 1131 5.4E-26 T 06-07-2017 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK77_RS19310 80006129970ef71d4b0e5501e92145e5 1171 Pfam PF04561 RNA polymerase Rpb2, domain 2 175 375 2.3E-25 T 06-07-2017 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK77_RS19310 80006129970ef71d4b0e5501e92145e5 1171 ProSitePatterns PS01166 RNA polymerases beta chain signature. 878 890 - T 06-07-2017 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK77_RS19310 80006129970ef71d4b0e5501e92145e5 1171 Pfam PF10385 RNA polymerase beta subunit external 1 domain 512 578 1.3E-27 T 06-07-2017 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK77_RS19310 80006129970ef71d4b0e5501e92145e5 1171 Pfam PF04565 RNA polymerase Rpb2, domain 3 434 502 1.3E-28 T 06-07-2017 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK77_RS19310 80006129970ef71d4b0e5501e92145e5 1171 Gene3D G3DSA:2.40.50.150 743 874 6.9E-57 T 06-07-2017 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK77_RS19310 80006129970ef71d4b0e5501e92145e5 1171 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 33 1133 12.291 T 06-07-2017 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK77_RS19310 80006129970ef71d4b0e5501e92145e5 1171 Gene3D G3DSA:3.90.1110.10 177 350 2.0E-64 T 06-07-2017 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK77_RS19310 80006129970ef71d4b0e5501e92145e5 1171 Pfam PF00562 RNA polymerase Rpb2, domain 6 639 1055 1.2E-158 T 06-07-2017 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAK77_RS17645 47ea476953189d06ed38ce845261df9e 481 Gene3D G3DSA:1.20.1250.20 243 460 8.4E-8 T 06-07-2017 CAK77_RS17645 47ea476953189d06ed38ce845261df9e 481 Gene3D G3DSA:1.20.1250.20 37 214 2.0E-12 T 06-07-2017 CAK77_RS17645 47ea476953189d06ed38ce845261df9e 481 SUPERFAMILY SSF103473 37 463 3.79E-32 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK77_RS17645 47ea476953189d06ed38ce845261df9e 481 Pfam PF07690 Major Facilitator Superfamily 50 421 6.8E-14 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK77_RS11390 1e737328639f06d6ec0faf7194bcfcdc 313 Gene3D G3DSA:3.40.50.1370 144 296 9.3E-60 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CAK77_RS11390 1e737328639f06d6ec0faf7194bcfcdc 313 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 8 309 7.2E-115 T 06-07-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CAK77_RS11390 1e737328639f06d6ec0faf7194bcfcdc 313 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 8 146 2.5E-44 T 06-07-2017 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 CAK77_RS11390 1e737328639f06d6ec0faf7194bcfcdc 313 Gene3D G3DSA:3.40.50.1370 3 143 3.6E-50 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CAK77_RS11390 1e737328639f06d6ec0faf7194bcfcdc 313 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 51 70 4.6E-26 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CAK77_RS11390 1e737328639f06d6ec0faf7194bcfcdc 313 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 274 297 4.6E-26 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CAK77_RS11390 1e737328639f06d6ec0faf7194bcfcdc 313 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 262 271 4.6E-26 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CAK77_RS11390 1e737328639f06d6ec0faf7194bcfcdc 313 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 133 144 4.6E-26 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CAK77_RS11390 1e737328639f06d6ec0faf7194bcfcdc 313 SUPERFAMILY SSF53671 4 311 1.83E-98 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CAK77_RS11390 1e737328639f06d6ec0faf7194bcfcdc 313 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 152 307 5.1E-53 T 06-07-2017 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 CAK77_RS11390 1e737328639f06d6ec0faf7194bcfcdc 313 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 51 58 - T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CAK77_RS11390 1e737328639f06d6ec0faf7194bcfcdc 313 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 7 310 75.111 T 06-07-2017 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 CAK77_RS11390 1e737328639f06d6ec0faf7194bcfcdc 313 PRINTS PR00102 Ornithine carbamoyltransferase signature 226 236 4.0E-28 T 06-07-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CAK77_RS11390 1e737328639f06d6ec0faf7194bcfcdc 313 PRINTS PR00102 Ornithine carbamoyltransferase signature 49 63 4.0E-28 T 06-07-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CAK77_RS11390 1e737328639f06d6ec0faf7194bcfcdc 313 PRINTS PR00102 Ornithine carbamoyltransferase signature 122 136 4.0E-28 T 06-07-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CAK77_RS11390 1e737328639f06d6ec0faf7194bcfcdc 313 PRINTS PR00102 Ornithine carbamoyltransferase signature 82 95 4.0E-28 T 06-07-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CAK77_RS11390 1e737328639f06d6ec0faf7194bcfcdc 313 PRINTS PR00102 Ornithine carbamoyltransferase signature 288 299 4.0E-28 T 06-07-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CAK77_RS20900 060a5b585daa0f3bff8641fa065e7c1a 133 Pfam PF12680 SnoaL-like domain 13 115 9.4E-10 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain CAK77_RS20900 060a5b585daa0f3bff8641fa065e7c1a 133 SUPERFAMILY SSF54427 10 125 7.11E-21 T 06-07-2017 IPR032710 NTF2-like domain CAK77_RS20900 060a5b585daa0f3bff8641fa065e7c1a 133 Gene3D G3DSA:3.10.450.50 9 126 2.3E-24 T 06-07-2017 IPR032710 NTF2-like domain CAK77_RS12435 476e9bd539dea01672d5664c737176e8 122 Pfam PF12840 Helix-turn-helix domain 13 70 2.6E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS12435 476e9bd539dea01672d5664c737176e8 122 SMART SM00418 13 91 3.6E-26 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK77_RS12435 476e9bd539dea01672d5664c737176e8 122 SUPERFAMILY SSF46785 9 89 5.97E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS12435 476e9bd539dea01672d5664c737176e8 122 Gene3D G3DSA:1.10.10.10 9 93 4.0E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS12435 476e9bd539dea01672d5664c737176e8 122 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 47 62 2.3E-10 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK77_RS12435 476e9bd539dea01672d5664c737176e8 122 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 15 30 2.3E-10 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK77_RS12435 476e9bd539dea01672d5664c737176e8 122 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 62 77 2.3E-10 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK77_RS05145 bb547f7b8dd0d39ee952febd16360fec 471 SUPERFAMILY SSF53474 153 442 7.03E-30 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS05145 bb547f7b8dd0d39ee952febd16360fec 471 Pfam PF00756 Putative esterase 177 345 8.5E-10 T 06-07-2017 IPR000801 Putative esterase Reactome: R-HSA-156590 CAK77_RS05145 bb547f7b8dd0d39ee952febd16360fec 471 Gene3D G3DSA:3.40.50.1820 386 444 2.2E-42 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS05145 bb547f7b8dd0d39ee952febd16360fec 471 Gene3D G3DSA:3.40.50.1820 156 354 2.2E-42 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS15420 01695555058fef7e295cce5508945484 749 SUPERFAMILY SSF53056 509 727 1.02E-49 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CAK77_RS15420 01695555058fef7e295cce5508945484 749 Pfam PF00916 Sulfate permease family 18 376 2.4E-78 T 06-07-2017 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 CAK77_RS15420 01695555058fef7e295cce5508945484 749 Gene3D G3DSA:3.40.1050.10 524 728 2.4E-59 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CAK77_RS15420 01695555058fef7e295cce5508945484 749 Pfam PF00484 Carbonic anhydrase 562 722 1.7E-41 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CAK77_RS15420 01695555058fef7e295cce5508945484 749 SMART SM00947 555 726 4.0E-51 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CAK77_RS23300 12ef0f0474a7f3a6e5ccde54b1d50f91 258 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 11 192 0.001 T 06-07-2017 CAK77_RS23300 12ef0f0474a7f3a6e5ccde54b1d50f91 258 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 247 4.3E-61 T 06-07-2017 CAK77_RS23300 12ef0f0474a7f3a6e5ccde54b1d50f91 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 8.8E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS23300 12ef0f0474a7f3a6e5ccde54b1d50f91 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 8.8E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS23300 12ef0f0474a7f3a6e5ccde54b1d50f91 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 8.8E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS23300 12ef0f0474a7f3a6e5ccde54b1d50f91 258 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK77_RS23300 12ef0f0474a7f3a6e5ccde54b1d50f91 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 8.1E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS23300 12ef0f0474a7f3a6e5ccde54b1d50f91 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 8.1E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS23300 12ef0f0474a7f3a6e5ccde54b1d50f91 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 8.1E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS23300 12ef0f0474a7f3a6e5ccde54b1d50f91 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 8.1E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS23300 12ef0f0474a7f3a6e5ccde54b1d50f91 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 8.1E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS23300 12ef0f0474a7f3a6e5ccde54b1d50f91 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 8.1E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS23300 12ef0f0474a7f3a6e5ccde54b1d50f91 258 Gene3D G3DSA:3.40.50.720 8 248 3.8E-79 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS23300 12ef0f0474a7f3a6e5ccde54b1d50f91 258 SUPERFAMILY SSF51735 9 248 1.65E-75 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS20435 79fb85586b22e060735cca8cc473baba 274 Gene3D G3DSA:3.20.20.60 2 223 5.4E-51 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAK77_RS20435 79fb85586b22e060735cca8cc473baba 274 Pfam PF13714 Phosphoenolpyruvate phosphomutase 11 224 1.5E-53 T 06-07-2017 CAK77_RS20435 79fb85586b22e060735cca8cc473baba 274 SUPERFAMILY SSF51621 8 214 1.52E-45 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAK77_RS03380 7f1b0f9b77c92d77ce9321a2c481ede9 408 Pfam PF12870 Domain of unknown function (DUF4878) 120 218 5.5E-23 T 06-07-2017 IPR024267 Domain of unknown function (DUF4878) CAK77_RS03380 7f1b0f9b77c92d77ce9321a2c481ede9 408 SUPERFAMILY SSF81995 3 76 3.92E-7 T 06-07-2017 CAK77_RS22850 5a699b107331adb856845fe97e36254f 276 ProSitePatterns PS00383 Tyrosine specific protein phosphatases active site. 164 174 - T 06-07-2017 IPR016130 Protein-tyrosine phosphatase, active site GO:0004725|GO:0016311|GO:0016791 CAK77_RS22850 5a699b107331adb856845fe97e36254f 276 Pfam PF13350 Tyrosine phosphatase family 16 275 1.1E-55 T 06-07-2017 IPR026893 Tyrosine/serine-protein phosphatase IphP-type CAK77_RS22850 5a699b107331adb856845fe97e36254f 276 SUPERFAMILY SSF52799 16 275 7.48E-47 T 06-07-2017 IPR029021 Protein-tyrosine phosphatase-like CAK77_RS22850 5a699b107331adb856845fe97e36254f 276 Gene3D G3DSA:3.90.190.10 139 200 9.3E-17 T 06-07-2017 IPR029021 Protein-tyrosine phosphatase-like CAK77_RS22850 5a699b107331adb856845fe97e36254f 276 Gene3D G3DSA:3.90.190.10 17 100 9.3E-17 T 06-07-2017 IPR029021 Protein-tyrosine phosphatase-like CAK77_RS08760 8c0f08a72b310d701171e7c4d3d98bb6 271 SUPERFAMILY SSF161098 3 271 2.62E-66 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS08760 8c0f08a72b310d701171e7c4d3d98bb6 271 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 82 265 1.0E-20 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS08760 8c0f08a72b310d701171e7c4d3d98bb6 271 Gene3D G3DSA:1.10.3720.10 3 259 2.0E-61 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS20105 eda10f5b6e31a05988aa9a2be1558475 315 SUPERFAMILY SSF53067 2 125 3.11E-30 T 06-07-2017 CAK77_RS20105 eda10f5b6e31a05988aa9a2be1558475 315 SUPERFAMILY SSF53067 130 305 5.83E-33 T 06-07-2017 CAK77_RS20105 eda10f5b6e31a05988aa9a2be1558475 315 Gene3D G3DSA:3.30.420.150 125 305 3.3E-46 T 06-07-2017 CAK77_RS20105 eda10f5b6e31a05988aa9a2be1558475 315 Pfam PF02541 Ppx/GppA phosphatase family 17 307 1.6E-85 T 06-07-2017 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 CAK77_RS20105 eda10f5b6e31a05988aa9a2be1558475 315 Gene3D G3DSA:3.30.420.40 2 122 7.4E-34 T 06-07-2017 CAK77_RS00280 5e93376985cf8d497a1530e83bd0d3e2 305 SUPERFAMILY SSF53850 88 296 4.89E-20 T 06-07-2017 CAK77_RS00280 5e93376985cf8d497a1530e83bd0d3e2 305 Pfam PF03466 LysR substrate binding domain 87 293 3.5E-20 T 06-07-2017 IPR005119 LysR, substrate-binding CAK77_RS00280 5e93376985cf8d497a1530e83bd0d3e2 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 1.2E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK77_RS00280 5e93376985cf8d497a1530e83bd0d3e2 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 1.2E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK77_RS00280 5e93376985cf8d497a1530e83bd0d3e2 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 1.2E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK77_RS00280 5e93376985cf8d497a1530e83bd0d3e2 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 61 1.2E-20 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK77_RS00280 5e93376985cf8d497a1530e83bd0d3e2 305 SUPERFAMILY SSF46785 4 85 3.1E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS00280 5e93376985cf8d497a1530e83bd0d3e2 305 Gene3D G3DSA:1.10.10.10 4 84 2.5E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS00280 5e93376985cf8d497a1530e83bd0d3e2 305 Gene3D G3DSA:3.40.190.10 88 201 9.9E-16 T 06-07-2017 CAK77_RS10070 e846890e670dd28a51dba6b7c66aa931 505 Gene3D G3DSA:3.50.50.60 180 209 8.6E-9 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS10070 e846890e670dd28a51dba6b7c66aa931 505 Gene3D G3DSA:3.50.50.60 290 344 8.6E-9 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS10070 e846890e670dd28a51dba6b7c66aa931 505 Gene3D G3DSA:3.50.50.60 4 179 2.8E-67 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS10070 e846890e670dd28a51dba6b7c66aa931 505 Gene3D G3DSA:3.50.50.60 387 489 2.8E-67 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS10070 e846890e670dd28a51dba6b7c66aa931 505 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 12 206 1.7E-16 T 06-07-2017 CAK77_RS10070 e846890e670dd28a51dba6b7c66aa931 505 SUPERFAMILY SSF51905 284 459 1.78E-15 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS10070 e846890e670dd28a51dba6b7c66aa931 505 SUPERFAMILY SSF51905 7 223 2.75E-49 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS03720 687057913fb14e72ae2adb0ae5b2fccc 313 SUPERFAMILY SSF161098 92 287 2.9E-19 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS03720 687057913fb14e72ae2adb0ae5b2fccc 313 Gene3D G3DSA:1.10.3720.10 91 303 2.0E-17 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS03720 687057913fb14e72ae2adb0ae5b2fccc 313 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 307 2.3E-22 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS07870 dc9ed4e3a6961ac53cdedcf8c1a6bec0 557 Pfam PF00005 ABC transporter 21 187 2.5E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK77_RS07870 dc9ed4e3a6961ac53cdedcf8c1a6bec0 557 Pfam PF00005 ABC transporter 337 470 7.2E-20 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK77_RS07870 dc9ed4e3a6961ac53cdedcf8c1a6bec0 557 TIGRFAM TIGR03719 ABC_ABC_ChvD: ATP-binding cassette protein, ChvD family 3 554 1.7E-266 T 06-07-2017 IPR022374 ABC transporter, ATP-binding protein, ChvD CAK77_RS07870 dc9ed4e3a6961ac53cdedcf8c1a6bec0 557 SUPERFAMILY SSF52540 8 237 7.36E-49 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS07870 dc9ed4e3a6961ac53cdedcf8c1a6bec0 557 Gene3D G3DSA:3.40.50.300 8 104 2.6E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS07870 dc9ed4e3a6961ac53cdedcf8c1a6bec0 557 Gene3D G3DSA:3.40.50.300 137 284 2.6E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS07870 dc9ed4e3a6961ac53cdedcf8c1a6bec0 557 Gene3D G3DSA:3.40.50.300 335 532 5.3E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS07870 dc9ed4e3a6961ac53cdedcf8c1a6bec0 557 SMART SM00382 345 515 3.3E-7 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS07870 dc9ed4e3a6961ac53cdedcf8c1a6bec0 557 SMART SM00382 30 232 2.7E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS07870 dc9ed4e3a6961ac53cdedcf8c1a6bec0 557 ProSitePatterns PS00211 ABC transporters family signature. 442 456 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK77_RS07870 dc9ed4e3a6961ac53cdedcf8c1a6bec0 557 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK77_RS07870 dc9ed4e3a6961ac53cdedcf8c1a6bec0 557 SUPERFAMILY SSF52540 307 506 6.88E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS07870 dc9ed4e3a6961ac53cdedcf8c1a6bec0 557 Pfam PF12848 ABC transporter 226 301 4.7E-12 T 06-07-2017 IPR032781 ABC-transporter extension domain CAK77_RS11720 a6559bab24a5a232d8e82351f481734f 321 Gene3D G3DSA:3.30.2010.10 148 203 3.4E-10 T 06-07-2017 CAK77_RS11720 a6559bab24a5a232d8e82351f481734f 321 Pfam PF01435 Peptidase family M48 150 209 1.9E-9 T 06-07-2017 IPR001915 Peptidase M48 GO:0004222|GO:0006508 CAK77_RS20740 ee81eabc87257b644328ee982babda64 420 Pfam PF07690 Major Facilitator Superfamily 37 235 7.8E-10 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK77_RS20740 ee81eabc87257b644328ee982babda64 420 Pfam PF07690 Major Facilitator Superfamily 240 416 1.2E-13 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK77_RS20740 ee81eabc87257b644328ee982babda64 420 Gene3D G3DSA:1.20.1250.20 230 414 1.7E-20 T 06-07-2017 CAK77_RS20740 ee81eabc87257b644328ee982babda64 420 Gene3D G3DSA:1.20.1250.20 33 209 1.2E-12 T 06-07-2017 CAK77_RS20740 ee81eabc87257b644328ee982babda64 420 SUPERFAMILY SSF103473 28 408 4.58E-42 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK77_RS00450 ff05a2a329f69bb30223741bb1c326d2 245 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 22 242 4.7E-33 T 06-07-2017 CAK77_RS00450 ff05a2a329f69bb30223741bb1c326d2 245 Gene3D G3DSA:3.40.50.720 10 244 1.6E-45 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS00450 ff05a2a329f69bb30223741bb1c326d2 245 SUPERFAMILY SSF51735 10 244 1.58E-44 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS00450 ff05a2a329f69bb30223741bb1c326d2 245 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 13 186 0.0033 T 06-07-2017 CAK77_RS00450 ff05a2a329f69bb30223741bb1c326d2 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 8.1E-16 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS00450 ff05a2a329f69bb30223741bb1c326d2 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 8.1E-16 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS00450 ff05a2a329f69bb30223741bb1c326d2 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 8.1E-16 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS00450 ff05a2a329f69bb30223741bb1c326d2 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 8.1E-16 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS11010 985a3043d8c6815c8a94060fc4631044 130 SUPERFAMILY SSF51182 16 125 3.78E-21 T 06-07-2017 IPR011051 RmlC-like cupin domain CAK77_RS11010 985a3043d8c6815c8a94060fc4631044 130 Hamap MF_01255 L-ectoine synthase [ectC]. 1 127 35.653 T 06-07-2017 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108|KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAK77_RS11010 985a3043d8c6815c8a94060fc4631044 130 Gene3D G3DSA:2.60.120.10 17 110 3.3E-15 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK77_RS11010 985a3043d8c6815c8a94060fc4631044 130 Pfam PF06339 Ectoine synthase 1 125 3.0E-54 T 06-07-2017 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108|KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAK77_RS11010 985a3043d8c6815c8a94060fc4631044 130 ProDom PD080544 SYNTHASE 4.2.1.- LYASE L-ECTOINE DEHYDRATASE N-ACETYLDIAMINOBUTYRATE ECTOINE ENZYME SYNTHASE:ECTOINE ECTC 1 117 2.0E-46 T 06-07-2017 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108|KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAK77_RS09625 9ad95c2939d451c20999aad60a37613a 142 Pfam PF04075 Domain of unknown function (DUF385) 12 140 1.5E-37 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CAK77_RS09625 9ad95c2939d451c20999aad60a37613a 142 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 30 139 9.7E-30 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CAK77_RS13190 683c5a2eeafaf07d1b92d8e4da88eee0 713 SUPERFAMILY SSF51445 144 482 8.07E-135 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily CAK77_RS13190 683c5a2eeafaf07d1b92d8e4da88eee0 713 SUPERFAMILY SSF51445 511 587 8.07E-135 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily CAK77_RS13190 683c5a2eeafaf07d1b92d8e4da88eee0 713 SMART SM00642 169 579 4.0E-8 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CAK77_RS13190 683c5a2eeafaf07d1b92d8e4da88eee0 713 SUPERFAMILY SSF81296 10 158 5.8E-42 T 06-07-2017 IPR014756 Immunoglobulin E-set CAK77_RS13190 683c5a2eeafaf07d1b92d8e4da88eee0 713 Gene3D G3DSA:2.60.40.1180 601 710 7.0E-32 T 06-07-2017 IPR013780 Glycosyl hydrolase, all-beta CAK77_RS13190 683c5a2eeafaf07d1b92d8e4da88eee0 713 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 15 101 3.5E-20 T 06-07-2017 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 CAK77_RS13190 683c5a2eeafaf07d1b92d8e4da88eee0 713 SUPERFAMILY SSF51011 601 710 1.73E-25 T 06-07-2017 CAK77_RS13190 683c5a2eeafaf07d1b92d8e4da88eee0 713 Gene3D G3DSA:2.60.40.10 10 162 2.0E-58 T 06-07-2017 IPR013783 Immunoglobulin-like fold CAK77_RS13190 683c5a2eeafaf07d1b92d8e4da88eee0 713 Pfam PF00128 Alpha amylase, catalytic domain 199 309 2.2E-9 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CAK77_RS13190 683c5a2eeafaf07d1b92d8e4da88eee0 713 Pfam PF00128 Alpha amylase, catalytic domain 322 542 5.1E-7 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CAK77_RS13190 683c5a2eeafaf07d1b92d8e4da88eee0 713 Gene3D G3DSA:3.20.20.80 163 587 5.2E-124 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAK77_RS13190 683c5a2eeafaf07d1b92d8e4da88eee0 713 TIGRFAM TIGR02100 glgX_debranch: glycogen debranching enzyme GlgX 11 710 4.5E-295 T 06-07-2017 IPR011837 Glycogen debranching enzyme, GlgX type GO:0004133|GO:0004553|GO:0005980 CAK77_RS06765 cf9885979010efe1477c1ca418a5018f 192 Gene3D G3DSA:1.10.340.30 7 184 4.0E-73 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CAK77_RS06765 cf9885979010efe1477c1ca418a5018f 192 TIGRFAM TIGR00624 tag: DNA-3-methyladenine glycosylase I 8 185 7.6E-81 T 06-07-2017 IPR004597 DNA-3-methyladenine glycosylase I GO:0006284|GO:0008725 CAK77_RS06765 cf9885979010efe1477c1ca418a5018f 192 SUPERFAMILY SSF48150 7 184 5.81E-68 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CAK77_RS06765 cf9885979010efe1477c1ca418a5018f 192 Pfam PF03352 Methyladenine glycosylase 18 183 9.1E-69 T 06-07-2017 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 CAK77_RS08350 b6a1de041b3eb9c6ca5e586e1902a75d 279 Pfam PF08379 Bacterial transglutaminase-like N-terminal region 4 82 4.3E-18 T 06-07-2017 IPR013589 Bacterial transglutaminase-like, N-terminal CAK77_RS08350 b6a1de041b3eb9c6ca5e586e1902a75d 279 SUPERFAMILY SSF54001 8 260 2.66E-36 T 06-07-2017 CAK77_RS08350 b6a1de041b3eb9c6ca5e586e1902a75d 279 Gene3D G3DSA:3.90.260.10 163 245 5.9E-13 T 06-07-2017 IPR002931 Transglutaminase-like CAK77_RS08350 b6a1de041b3eb9c6ca5e586e1902a75d 279 Pfam PF01841 Transglutaminase-like superfamily 128 232 9.8E-24 T 06-07-2017 IPR002931 Transglutaminase-like CAK77_RS08350 b6a1de041b3eb9c6ca5e586e1902a75d 279 SMART SM00460 167 234 8.9E-20 T 06-07-2017 IPR002931 Transglutaminase-like CAK77_RS18655 f9d5b8e84d456d8048d87ec81438343f 476 SUPERFAMILY SSF53383 27 459 5.13E-126 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK77_RS18655 f9d5b8e84d456d8048d87ec81438343f 476 Gene3D G3DSA:3.40.640.10 81 359 6.1E-29 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK77_RS18655 f9d5b8e84d456d8048d87ec81438343f 476 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 54 396 1.7E-72 T 06-07-2017 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 CAK77_RS18655 f9d5b8e84d456d8048d87ec81438343f 476 TIGRFAM TIGR01788 Glu-decarb-GAD: glutamate decarboxylase 25 459 5.2E-200 T 06-07-2017 IPR010107 Glutamate decarboxylase GO:0004351|GO:0006536|GO:0030170 KEGG: 00250+4.1.1.15|KEGG: 00410+4.1.1.15|KEGG: 00430+4.1.1.15|KEGG: 00650+4.1.1.15|MetaCyc: PWY-4321 CAK77_RS10410 b11a7c038b8fb23a1bcc7b6156f70318 422 ProSitePatterns PS00667 Respiratory-chain NADH dehydrogenase subunit 1 signature 1. 60 75 - T 06-07-2017 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS10410 b11a7c038b8fb23a1bcc7b6156f70318 422 Pfam PF00146 NADH dehydrogenase 21 340 3.1E-123 T 06-07-2017 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS10410 b11a7c038b8fb23a1bcc7b6156f70318 422 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 14 347 24.766 T 06-07-2017 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS10410 b11a7c038b8fb23a1bcc7b6156f70318 422 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 224 237 - T 06-07-2017 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS16135 da4d0cbd9bd329b8a89e2b4e3bcfda72 178 Pfam PF00578 AhpC/TSA family 49 154 6.5E-14 T 06-07-2017 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CAK77_RS16135 da4d0cbd9bd329b8a89e2b4e3bcfda72 178 Gene3D G3DSA:3.40.30.10 47 177 4.3E-30 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK77_RS16135 da4d0cbd9bd329b8a89e2b4e3bcfda72 178 SUPERFAMILY SSF52833 48 177 2.66E-28 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK77_RS18720 eebe593064464e3a252d46cef74e4916 96 Gene3D G3DSA:1.10.287.1060 2 94 4.9E-21 T 06-07-2017 CAK77_RS18720 eebe593064464e3a252d46cef74e4916 96 Pfam PF06013 Proteins of 100 residues with WXG 3 88 2.9E-10 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like CAK77_RS18720 eebe593064464e3a252d46cef74e4916 96 SUPERFAMILY SSF140453 2 94 1.96E-20 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like CAK77_RS18720 eebe593064464e3a252d46cef74e4916 96 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 3 91 7.3E-15 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like CAK77_RS10350 1d3cf6f4237a2d4450aa0ce9598eb9fb 1250 SMART SM01018 664 751 5.0E-41 T 06-07-2017 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAK77_RS10350 1d3cf6f4237a2d4450aa0ce9598eb9fb 1250 Gene3D G3DSA:3.20.20.20 370 642 4.8E-113 T 06-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAK77_RS10350 1d3cf6f4237a2d4450aa0ce9598eb9fb 1250 PIRSF PIRSF000381 10 1217 0.0 T 06-07-2017 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0008898|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAK77_RS10350 1d3cf6f4237a2d4450aa0ce9598eb9fb 1250 Gene3D G3DSA:3.10.196.10 975 1249 9.3E-111 T 06-07-2017 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0005622|GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAK77_RS10350 1d3cf6f4237a2d4450aa0ce9598eb9fb 1250 Pfam PF00809 Pterin binding enzyme 366 604 2.0E-58 T 06-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAK77_RS10350 1d3cf6f4237a2d4450aa0ce9598eb9fb 1250 SUPERFAMILY SSF56507 918 1249 5.62E-128 T 06-07-2017 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0005622|GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAK77_RS10350 1d3cf6f4237a2d4450aa0ce9598eb9fb 1250 SUPERFAMILY SSF52242 761 911 8.11E-45 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CAK77_RS10350 1d3cf6f4237a2d4450aa0ce9598eb9fb 1250 Gene3D G3DSA:3.40.50.280 762 912 2.3E-64 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CAK77_RS10350 1d3cf6f4237a2d4450aa0ce9598eb9fb 1250 Gene3D G3DSA:1.10.1240.10 659 748 2.1E-35 T 06-07-2017 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAK77_RS10350 1d3cf6f4237a2d4450aa0ce9598eb9fb 1250 SUPERFAMILY SSF51717 362 636 5.76E-89 T 06-07-2017 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAK77_RS10350 1d3cf6f4237a2d4450aa0ce9598eb9fb 1250 Pfam PF02965 Vitamin B12 dependent methionine synthase, activation domain 955 1230 1.3E-120 T 06-07-2017 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0005622|GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAK77_RS10350 1d3cf6f4237a2d4450aa0ce9598eb9fb 1250 Pfam PF02607 B12 binding domain 666 743 2.4E-23 T 06-07-2017 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAK77_RS10350 1d3cf6f4237a2d4450aa0ce9598eb9fb 1250 SUPERFAMILY SSF47644 660 750 1.83E-25 T 06-07-2017 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAK77_RS10350 1d3cf6f4237a2d4450aa0ce9598eb9fb 1250 TIGRFAM TIGR02082 metH: methionine synthase 20 1214 0.0 T 06-07-2017 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0008898|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAK77_RS10350 1d3cf6f4237a2d4450aa0ce9598eb9fb 1250 Pfam PF02310 B12 binding domain 765 855 1.7E-19 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CAK77_RS10350 1d3cf6f4237a2d4450aa0ce9598eb9fb 1250 Pfam PF02574 Homocysteine S-methyltransferase 25 331 1.4E-86 T 06-07-2017 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CAK77_RS10350 1d3cf6f4237a2d4450aa0ce9598eb9fb 1250 Gene3D G3DSA:3.20.20.330 13 369 9.7E-121 T 06-07-2017 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CAK77_RS10350 1d3cf6f4237a2d4450aa0ce9598eb9fb 1250 SUPERFAMILY SSF82282 16 405 4.19E-113 T 06-07-2017 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CAK77_RS13590 92b2365b11f9baeb3482a00394a5c05f 445 SUPERFAMILY SSF103473 30 435 7.72E-40 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK77_RS13590 92b2365b11f9baeb3482a00394a5c05f 445 Gene3D G3DSA:1.20.1250.20 40 229 2.2E-18 T 06-07-2017 CAK77_RS13590 92b2365b11f9baeb3482a00394a5c05f 445 Gene3D G3DSA:1.20.1250.20 257 434 5.4E-8 T 06-07-2017 CAK77_RS13590 92b2365b11f9baeb3482a00394a5c05f 445 Pfam PF07690 Major Facilitator Superfamily 48 390 2.1E-24 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK77_RS24045 71865304a1bc85a8b5358cc7be05a225 510 Pfam PF13450 NAD(P)-binding Rossmann-like domain 16 69 2.1E-7 T 06-07-2017 CAK77_RS24045 71865304a1bc85a8b5358cc7be05a225 510 SUPERFAMILY SSF51905 160 358 1.25E-21 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS24045 71865304a1bc85a8b5358cc7be05a225 510 Pfam PF00743 Flavin-binding monooxygenase-like 87 229 5.3E-5 T 06-07-2017 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 CAK77_RS24045 71865304a1bc85a8b5358cc7be05a225 510 SUPERFAMILY SSF51905 7 228 7.5E-44 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS24045 71865304a1bc85a8b5358cc7be05a225 510 Gene3D G3DSA:3.50.50.60 338 476 9.0E-5 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS24045 71865304a1bc85a8b5358cc7be05a225 510 Gene3D G3DSA:3.50.50.60 8 230 1.4E-48 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS08705 79c50521627edd75d80f6f931853b8d2 634 SMART SM00400 37 91 2.9E-34 T 06-07-2017 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 CAK77_RS08705 79c50521627edd75d80f6f931853b8d2 634 TIGRFAM TIGR01391 dnaG: DNA primase 5 423 3.1E-112 T 06-07-2017 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 CAK77_RS08705 79c50521627edd75d80f6f931853b8d2 634 Pfam PF13662 Toprim domain 263 333 1.6E-14 T 06-07-2017 IPR006171 Toprim domain CAK77_RS08705 79c50521627edd75d80f6f931853b8d2 634 Gene3D G3DSA:1.20.50.20 375 430 8.3E-14 T 06-07-2017 CAK77_RS08705 79c50521627edd75d80f6f931853b8d2 634 Pfam PF08275 DNA primase catalytic core, N-terminal domain 127 254 4.2E-35 T 06-07-2017 IPR013264 DNA primase, catalytic core, N-terminal CAK77_RS08705 79c50521627edd75d80f6f931853b8d2 634 SMART SM00766 480 610 5.3E-22 T 06-07-2017 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 CAK77_RS08705 79c50521627edd75d80f6f931853b8d2 634 Hamap MF_00974 DNA primase [dnaG]. 4 615 25.66 T 06-07-2017 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 CAK77_RS08705 79c50521627edd75d80f6f931853b8d2 634 Gene3D G3DSA:3.40.1360.10 244 372 3.6E-38 T 06-07-2017 CAK77_RS08705 79c50521627edd75d80f6f931853b8d2 634 SUPERFAMILY SSF57783 4 100 1.26E-33 T 06-07-2017 CAK77_RS08705 79c50521627edd75d80f6f931853b8d2 634 Pfam PF01807 CHC2 zinc finger 6 101 1.9E-35 T 06-07-2017 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 CAK77_RS08705 79c50521627edd75d80f6f931853b8d2 634 Gene3D G3DSA:3.90.580.10 1 101 1.6E-37 T 06-07-2017 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 CAK77_RS08705 79c50521627edd75d80f6f931853b8d2 634 PIRSF PIRSF002811 2 621 1.1E-139 T 06-07-2017 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 CAK77_RS08705 79c50521627edd75d80f6f931853b8d2 634 Pfam PF08278 DNA primase DnaG DnaB-binding 481 609 2.4E-24 T 06-07-2017 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 CAK77_RS08705 79c50521627edd75d80f6f931853b8d2 634 Pfam PF10410 DnaB-helicase binding domain of primase 376 430 1.1E-16 T 06-07-2017 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 CAK77_RS08705 79c50521627edd75d80f6f931853b8d2 634 SMART SM00493 262 340 1.1E-14 T 06-07-2017 IPR006171 Toprim domain CAK77_RS08705 79c50521627edd75d80f6f931853b8d2 634 Gene3D G3DSA:3.90.980.10 117 243 4.6E-36 T 06-07-2017 IPR013264 DNA primase, catalytic core, N-terminal CAK77_RS08705 79c50521627edd75d80f6f931853b8d2 634 SUPERFAMILY SSF56731 117 432 8.63E-91 T 06-07-2017 CAK77_RS24305 24bea0b56629c77fd210028367e742d2 325 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 16 35 2.0E-37 T 06-07-2017 CAK77_RS24305 24bea0b56629c77fd210028367e742d2 325 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 155 173 2.0E-37 T 06-07-2017 CAK77_RS24305 24bea0b56629c77fd210028367e742d2 325 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 239 255 2.0E-37 T 06-07-2017 CAK77_RS24305 24bea0b56629c77fd210028367e742d2 325 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 266 288 2.0E-37 T 06-07-2017 CAK77_RS24305 24bea0b56629c77fd210028367e742d2 325 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 113 131 2.0E-37 T 06-07-2017 CAK77_RS24305 24bea0b56629c77fd210028367e742d2 325 Gene3D G3DSA:3.50.50.60 118 307 1.3E-38 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS24305 24bea0b56629c77fd210028367e742d2 325 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 15 313 2.3E-121 T 06-07-2017 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00240+1.8.1.9|KEGG: 00450+1.8.1.9 CAK77_RS24305 24bea0b56629c77fd210028367e742d2 325 SUPERFAMILY SSF51905 11 313 1.41E-54 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS24305 24bea0b56629c77fd210028367e742d2 325 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 15 302 1.5E-47 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS24305 24bea0b56629c77fd210028367e742d2 325 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 241 262 5.3E-78 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAK77_RS24305 24bea0b56629c77fd210028367e742d2 325 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 136 148 5.3E-78 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAK77_RS24305 24bea0b56629c77fd210028367e742d2 325 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 276 294 5.3E-78 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAK77_RS24305 24bea0b56629c77fd210028367e742d2 325 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 203 219 5.3E-78 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAK77_RS24305 24bea0b56629c77fd210028367e742d2 325 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 151 175 5.3E-78 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAK77_RS24305 24bea0b56629c77fd210028367e742d2 325 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 48 63 5.3E-78 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAK77_RS24305 24bea0b56629c77fd210028367e742d2 325 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 69 79 5.3E-78 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAK77_RS24305 24bea0b56629c77fd210028367e742d2 325 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 15 37 5.3E-78 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAK77_RS24305 24bea0b56629c77fd210028367e742d2 325 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 114 122 5.3E-78 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAK77_RS24305 24bea0b56629c77fd210028367e742d2 325 Gene3D G3DSA:3.50.50.60 13 117 8.8E-35 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS24305 24bea0b56629c77fd210028367e742d2 325 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 143 163 - T 06-07-2017 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 CAK77_RS00015 fabcf5af54f2611c7806a8a2acdee7e1 399 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 13 397 8.4E-106 T 06-07-2017 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAK77_RS00015 fabcf5af54f2611c7806a8a2acdee7e1 399 PIRSF PIRSF000804 13 398 2.8E-93 T 06-07-2017 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAK77_RS00015 fabcf5af54f2611c7806a8a2acdee7e1 399 SUPERFAMILY SSF55979 262 397 4.89E-29 T 06-07-2017 CAK77_RS00015 fabcf5af54f2611c7806a8a2acdee7e1 399 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 13 130 8.6E-36 T 06-07-2017 IPR022634 DNA polymerase III, beta chain, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAK77_RS00015 fabcf5af54f2611c7806a8a2acdee7e1 399 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 262 373 4.8E-34 T 06-07-2017 IPR022635 DNA polymerase III, beta chain, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAK77_RS00015 fabcf5af54f2611c7806a8a2acdee7e1 399 SUPERFAMILY SSF55979 140 263 3.45E-19 T 06-07-2017 CAK77_RS00015 fabcf5af54f2611c7806a8a2acdee7e1 399 SMART SM00480 29 378 2.1E-134 T 06-07-2017 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAK77_RS00015 fabcf5af54f2611c7806a8a2acdee7e1 399 SUPERFAMILY SSF55979 14 131 1.96E-23 T 06-07-2017 CAK77_RS00015 fabcf5af54f2611c7806a8a2acdee7e1 399 Gene3D G3DSA:3.10.150.10 266 398 1.5E-41 T 06-07-2017 CAK77_RS00015 fabcf5af54f2611c7806a8a2acdee7e1 399 Gene3D G3DSA:3.10.150.10 137 264 6.3E-29 T 06-07-2017 CAK77_RS00015 fabcf5af54f2611c7806a8a2acdee7e1 399 Gene3D G3DSA:3.10.150.10 12 132 4.1E-31 T 06-07-2017 CAK77_RS00015 fabcf5af54f2611c7806a8a2acdee7e1 399 Pfam PF02767 DNA polymerase III beta subunit, central domain 140 260 1.3E-32 T 06-07-2017 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAK77_RS01670 4d93b10c4622cce84a44edd7c6d887a8 397 Gene3D G3DSA:3.40.710.10 63 363 1.5E-83 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK77_RS01670 4d93b10c4622cce84a44edd7c6d887a8 397 Pfam PF00144 Beta-lactamase 52 365 5.4E-69 T 06-07-2017 IPR001466 Beta-lactamase-related CAK77_RS01670 4d93b10c4622cce84a44edd7c6d887a8 397 SUPERFAMILY SSF56601 43 363 2.75E-84 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK77_RS03755 89b67ee95f954e680bc5992a1a27dc40 236 SUPERFAMILY SSF52499 19 232 5.49E-33 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAK77_RS03755 89b67ee95f954e680bc5992a1a27dc40 236 Gene3D G3DSA:3.40.50.850 17 234 2.2E-34 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAK77_RS03755 89b67ee95f954e680bc5992a1a27dc40 236 Pfam PF00857 Isochorismatase family 28 202 5.3E-24 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAK77_RS12885 4c3c5e98b17a45f367ef8f733388dccd 401 PIRSF PIRSF000429 2 401 2.3E-37 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 CAK77_RS12885 4c3c5e98b17a45f367ef8f733388dccd 401 Gene3D G3DSA:3.40.47.10 261 399 4.2E-8 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS12885 4c3c5e98b17a45f367ef8f733388dccd 401 Gene3D G3DSA:3.40.47.10 143 185 4.2E-8 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS12885 4c3c5e98b17a45f367ef8f733388dccd 401 Pfam PF00108 Thiolase, N-terminal domain 9 225 8.2E-8 T 06-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CAK77_RS12885 4c3c5e98b17a45f367ef8f733388dccd 401 SUPERFAMILY SSF53901 8 231 8.08E-40 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS12885 4c3c5e98b17a45f367ef8f733388dccd 401 SUPERFAMILY SSF53901 281 390 4.21E-20 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS12885 4c3c5e98b17a45f367ef8f733388dccd 401 Gene3D G3DSA:3.40.47.10 20 115 3.2E-25 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS12885 4c3c5e98b17a45f367ef8f733388dccd 401 Gene3D G3DSA:3.40.47.10 196 226 3.2E-25 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS11070 069b99ac7feb8d3f167876ecc3296b39 540 SUPERFAMILY SSF53720 66 514 3.27E-61 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAK77_RS11070 069b99ac7feb8d3f167876ecc3296b39 540 Pfam PF00171 Aldehyde dehydrogenase family 66 504 2.1E-51 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAK77_RS11070 069b99ac7feb8d3f167876ecc3296b39 540 Gene3D G3DSA:3.40.309.10 300 491 6.6E-32 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAK77_RS11070 069b99ac7feb8d3f167876ecc3296b39 540 Gene3D G3DSA:3.40.605.10 15 299 4.3E-28 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAK77_RS17940 a5fb8c37aa235ca491149f45fa4c6ff0 118 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 118 18.929 T 06-07-2017 IPR003482 Transcription factor WhiB CAK77_RS17940 a5fb8c37aa235ca491149f45fa4c6ff0 118 Pfam PF02467 Transcription factor WhiB 50 113 1.1E-26 T 06-07-2017 IPR003482 Transcription factor WhiB CAK77_RS08890 16615f13b8c3a253582bfa6430a5e4a9 347 Gene3D G3DSA:1.10.390.10 187 346 1.2E-40 T 06-07-2017 CAK77_RS08890 16615f13b8c3a253582bfa6430a5e4a9 347 Gene3D G3DSA:3.10.170.10 75 186 1.4E-38 T 06-07-2017 IPR013856 Peptidase M4 domain GO:0004222 CAK77_RS08890 16615f13b8c3a253582bfa6430a5e4a9 347 SUPERFAMILY SSF55486 77 347 1.26E-67 T 06-07-2017 CAK77_RS08890 16615f13b8c3a253582bfa6430a5e4a9 347 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 194 205 1.2E-26 T 06-07-2017 IPR023612 Peptidase M4 GO:0004222|GO:0006508 CAK77_RS08890 16615f13b8c3a253582bfa6430a5e4a9 347 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 137 157 1.2E-26 T 06-07-2017 IPR023612 Peptidase M4 GO:0004222|GO:0006508 CAK77_RS08890 16615f13b8c3a253582bfa6430a5e4a9 347 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 173 189 1.2E-26 T 06-07-2017 IPR023612 Peptidase M4 GO:0004222|GO:0006508 CAK77_RS08890 16615f13b8c3a253582bfa6430a5e4a9 347 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 269 285 1.2E-26 T 06-07-2017 IPR023612 Peptidase M4 GO:0004222|GO:0006508 CAK77_RS08890 16615f13b8c3a253582bfa6430a5e4a9 347 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 185 346 6.1E-37 T 06-07-2017 IPR001570 Peptidase M4, C-terminal GO:0004222 CAK77_RS08890 16615f13b8c3a253582bfa6430a5e4a9 347 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 104 182 2.2E-28 T 06-07-2017 IPR013856 Peptidase M4 domain GO:0004222 CAK77_RS15430 4f966ca47d9df0a9d20db12ef88aa27f 371 Gene3D G3DSA:3.40.50.1770 1 176 2.7E-56 T 06-07-2017 CAK77_RS15430 4f966ca47d9df0a9d20db12ef88aa27f 371 SMART SM01002 149 297 1.5E-81 T 06-07-2017 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain CAK77_RS15430 4f966ca47d9df0a9d20db12ef88aa27f 371 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 137 3.6E-45 T 06-07-2017 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal CAK77_RS15430 4f966ca47d9df0a9d20db12ef88aa27f 371 SUPERFAMILY SSF52283 305 360 1.02E-63 T 06-07-2017 CAK77_RS15430 4f966ca47d9df0a9d20db12ef88aa27f 371 SUPERFAMILY SSF52283 1 137 1.02E-63 T 06-07-2017 CAK77_RS15430 4f966ca47d9df0a9d20db12ef88aa27f 371 ProSitePatterns PS00836 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 1. 4 30 - T 06-07-2017 IPR008142 Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 GO:0016491|GO:0055114 Reactome: R-HSA-71403 CAK77_RS15430 4f966ca47d9df0a9d20db12ef88aa27f 371 TIGRFAM TIGR00518 alaDH: alanine dehydrogenase 1 370 1.4E-182 T 06-07-2017 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 CAK77_RS15430 4f966ca47d9df0a9d20db12ef88aa27f 371 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 173 198 - T 06-07-2017 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1|Reactome: R-HSA-71403 CAK77_RS15430 4f966ca47d9df0a9d20db12ef88aa27f 371 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 141 352 7.7E-82 T 06-07-2017 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain CAK77_RS15430 4f966ca47d9df0a9d20db12ef88aa27f 371 PIRSF PIRSF000183 1 371 9.0E-172 T 06-07-2017 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 CAK77_RS15430 4f966ca47d9df0a9d20db12ef88aa27f 371 SMART SM01003 4 137 5.2E-75 T 06-07-2017 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal CAK77_RS15430 4f966ca47d9df0a9d20db12ef88aa27f 371 Gene3D G3DSA:3.50.50.60 177 197 7.8E-8 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS15430 4f966ca47d9df0a9d20db12ef88aa27f 371 SUPERFAMILY SSF51735 137 303 2.44E-49 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS15430 4f966ca47d9df0a9d20db12ef88aa27f 371 Gene3D G3DSA:3.40.50.1770 198 359 1.4E-27 T 06-07-2017 CAK77_RS13245 12210807297cf2d427159b5fad57f7b8 175 Pfam PF08241 Methyltransferase domain 25 119 6.0E-16 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CAK77_RS13245 12210807297cf2d427159b5fad57f7b8 175 SUPERFAMILY SSF53335 6 171 8.83E-29 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS13245 12210807297cf2d427159b5fad57f7b8 175 Gene3D G3DSA:3.40.50.150 14 161 3.5E-24 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS04770 6a58a6b98e401a6c03a5b6386877d4a3 670 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 10 426 1.8E-69 T 06-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CAK77_RS04770 6a58a6b98e401a6c03a5b6386877d4a3 670 PRINTS PR01036 Tetracycline resistance protein TetB signature 103 123 3.8E-7 T 06-07-2017 CAK77_RS04770 6a58a6b98e401a6c03a5b6386877d4a3 670 PRINTS PR01036 Tetracycline resistance protein TetB signature 133 157 3.8E-7 T 06-07-2017 CAK77_RS04770 6a58a6b98e401a6c03a5b6386877d4a3 670 PRINTS PR01036 Tetracycline resistance protein TetB signature 397 416 3.8E-7 T 06-07-2017 CAK77_RS04770 6a58a6b98e401a6c03a5b6386877d4a3 670 PRINTS PR01036 Tetracycline resistance protein TetB signature 334 354 3.8E-7 T 06-07-2017 CAK77_RS04770 6a58a6b98e401a6c03a5b6386877d4a3 670 PRINTS PR01036 Tetracycline resistance protein TetB signature 198 216 3.8E-7 T 06-07-2017 CAK77_RS04770 6a58a6b98e401a6c03a5b6386877d4a3 670 Pfam PF07690 Major Facilitator Superfamily 14 407 2.9E-51 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK77_RS04770 6a58a6b98e401a6c03a5b6386877d4a3 670 Gene3D G3DSA:1.20.1250.20 456 482 2.6E-22 T 06-07-2017 CAK77_RS04770 6a58a6b98e401a6c03a5b6386877d4a3 670 Gene3D G3DSA:1.20.1250.20 259 417 2.6E-22 T 06-07-2017 CAK77_RS04770 6a58a6b98e401a6c03a5b6386877d4a3 670 Gene3D G3DSA:1.20.1250.20 10 180 1.6E-27 T 06-07-2017 CAK77_RS04770 6a58a6b98e401a6c03a5b6386877d4a3 670 SUPERFAMILY SSF103473 244 417 9.02E-69 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK77_RS04770 6a58a6b98e401a6c03a5b6386877d4a3 670 SUPERFAMILY SSF103473 456 479 9.02E-69 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK77_RS04770 6a58a6b98e401a6c03a5b6386877d4a3 670 SUPERFAMILY SSF103473 6 190 9.02E-69 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK77_RS04770 6a58a6b98e401a6c03a5b6386877d4a3 670 SUPERFAMILY SSF46785 550 607 6.2E-5 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS04770 6a58a6b98e401a6c03a5b6386877d4a3 670 ProSitePatterns PS00217 Sugar transport proteins signature 2. 105 130 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CAK77_RS08345 917d7d89925a247dbd279339f2dd4122 325 Pfam PF04168 A predicted alpha-helical domain with a conserved ER motif. 1 300 2.8E-77 T 06-07-2017 IPR007296 Domain of unknown function DUF403 CAK77_RS07510 8996bc546b175a6b78424d0b3fa32a19 1115 Gene3D G3DSA:3.40.1140.10 10 234 5.3E-21 T 06-07-2017 CAK77_RS07510 8996bc546b175a6b78424d0b3fa32a19 1115 SUPERFAMILY SSF52540 983 1070 5.04E-12 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS07510 8996bc546b175a6b78424d0b3fa32a19 1115 SUPERFAMILY SSF52540 335 343 5.04E-12 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS07510 8996bc546b175a6b78424d0b3fa32a19 1115 SUPERFAMILY SSF52540 688 740 5.04E-12 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS07510 8996bc546b175a6b78424d0b3fa32a19 1115 SUPERFAMILY SSF52540 12 161 5.04E-12 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS07510 8996bc546b175a6b78424d0b3fa32a19 1115 Pfam PF13558 Putative exonuclease SbcCD, C subunit 965 1055 1.6E-19 T 06-07-2017 CAK77_RS07510 8996bc546b175a6b78424d0b3fa32a19 1115 Pfam PF13555 P-loop containing region of AAA domain 13 71 4.0E-21 T 06-07-2017 CAK77_RS09615 6105fdd0911b4b5271794a361b12f62c 603 Gene3D G3DSA:3.40.50.980 336 401 5.0E-23 T 06-07-2017 CAK77_RS09615 6105fdd0911b4b5271794a361b12f62c 603 Gene3D G3DSA:3.40.50.980 194 286 5.0E-23 T 06-07-2017 CAK77_RS09615 6105fdd0911b4b5271794a361b12f62c 603 Gene3D G3DSA:3.30.300.30 466 588 1.1E-4 T 06-07-2017 CAK77_RS09615 6105fdd0911b4b5271794a361b12f62c 603 Pfam PF00501 AMP-binding enzyme 28 468 4.3E-95 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK77_RS09615 6105fdd0911b4b5271794a361b12f62c 603 Gene3D G3DSA:2.30.38.10 405 462 6.9E-20 T 06-07-2017 CAK77_RS09615 6105fdd0911b4b5271794a361b12f62c 603 SUPERFAMILY SSF56801 339 598 3.27E-113 T 06-07-2017 CAK77_RS09615 6105fdd0911b4b5271794a361b12f62c 603 SUPERFAMILY SSF56801 17 291 3.27E-113 T 06-07-2017 CAK77_RS09615 6105fdd0911b4b5271794a361b12f62c 603 ProSitePatterns PS00455 Putative AMP-binding domain signature. 187 198 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK77_RS09615 6105fdd0911b4b5271794a361b12f62c 603 Gene3D G3DSA:3.40.50.980 27 193 9.5E-36 T 06-07-2017 CAK77_RS03960 a964c7e496e05a41aa1a6913ed7ca2d5 125 SUPERFAMILY SSF54593 7 123 1.48E-18 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK77_RS03960 a964c7e496e05a41aa1a6913ed7ca2d5 125 Gene3D G3DSA:3.10.180.10 7 122 2.2E-18 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK77_RS16855 cd61beaa5201252f22b7277a26a337a5 564 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 260 314 - T 06-07-2017 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK77_RS16855 cd61beaa5201252f22b7277a26a337a5 564 SUPERFAMILY SSF81442 28 538 4.06E-174 T 06-07-2017 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK77_RS16855 cd61beaa5201252f22b7277a26a337a5 564 PRINTS PR01165 Cytochrome c oxidase subunit I signature 361 379 5.6E-100 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK77_RS16855 cd61beaa5201252f22b7277a26a337a5 564 PRINTS PR01165 Cytochrome c oxidase subunit I signature 208 227 5.6E-100 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK77_RS16855 cd61beaa5201252f22b7277a26a337a5 564 PRINTS PR01165 Cytochrome c oxidase subunit I signature 179 197 5.6E-100 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK77_RS16855 cd61beaa5201252f22b7277a26a337a5 564 PRINTS PR01165 Cytochrome c oxidase subunit I signature 147 159 5.6E-100 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK77_RS16855 cd61beaa5201252f22b7277a26a337a5 564 PRINTS PR01165 Cytochrome c oxidase subunit I signature 237 258 5.6E-100 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK77_RS16855 cd61beaa5201252f22b7277a26a337a5 564 PRINTS PR01165 Cytochrome c oxidase subunit I signature 326 347 5.6E-100 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK77_RS16855 cd61beaa5201252f22b7277a26a337a5 564 PRINTS PR01165 Cytochrome c oxidase subunit I signature 389 408 5.6E-100 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK77_RS16855 cd61beaa5201252f22b7277a26a337a5 564 PRINTS PR01165 Cytochrome c oxidase subunit I signature 30 55 5.6E-100 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK77_RS16855 cd61beaa5201252f22b7277a26a337a5 564 PRINTS PR01165 Cytochrome c oxidase subunit I signature 304 319 5.6E-100 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK77_RS16855 cd61beaa5201252f22b7277a26a337a5 564 PRINTS PR01165 Cytochrome c oxidase subunit I signature 77 100 5.6E-100 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK77_RS16855 cd61beaa5201252f22b7277a26a337a5 564 PRINTS PR01165 Cytochrome c oxidase subunit I signature 258 279 5.6E-100 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK77_RS16855 cd61beaa5201252f22b7277a26a337a5 564 PRINTS PR01165 Cytochrome c oxidase subunit I signature 104 128 5.6E-100 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK77_RS16855 cd61beaa5201252f22b7277a26a337a5 564 PRINTS PR01165 Cytochrome c oxidase subunit I signature 439 460 5.6E-100 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK77_RS16855 cd61beaa5201252f22b7277a26a337a5 564 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 40 483 1.8E-146 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK77_RS16855 cd61beaa5201252f22b7277a26a337a5 564 Gene3D G3DSA:1.20.210.10 24 552 3.0E-190 T 06-07-2017 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK77_RS16855 cd61beaa5201252f22b7277a26a337a5 564 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 32 536 1.4E-213 T 06-07-2017 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005507|GO:0005886|GO:0006810|GO:0022900|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 CAK77_RS23160 ea82a70cac9209c7a7e1ebffeea954b5 230 Pfam PF00355 Rieske [2Fe-2S] domain 125 200 1.5E-13 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK77_RS23160 ea82a70cac9209c7a7e1ebffeea954b5 230 Gene3D G3DSA:2.102.10.10 80 226 4.7E-27 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK77_RS23160 ea82a70cac9209c7a7e1ebffeea954b5 230 SUPERFAMILY SSF50022 122 227 2.36E-25 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK77_RS00675 ce7e353f8772a39275a1421f41f270f8 496 Pfam PF00743 Flavin-binding monooxygenase-like 7 347 9.0E-15 T 06-07-2017 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 CAK77_RS00675 ce7e353f8772a39275a1421f41f270f8 496 Gene3D G3DSA:3.50.50.60 302 460 8.1E-10 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS00675 ce7e353f8772a39275a1421f41f270f8 496 Gene3D G3DSA:3.50.50.60 2 216 8.3E-53 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS00675 ce7e353f8772a39275a1421f41f270f8 496 SUPERFAMILY SSF51905 1 387 4.78E-51 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS02795 1f666dfc4fc7659c8469358cc744ae83 172 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 3 132 3.8E-37 T 06-07-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CAK77_RS02795 1f666dfc4fc7659c8469358cc744ae83 172 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 4 132 3.7E-32 T 06-07-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CAK77_RS02795 1f666dfc4fc7659c8469358cc744ae83 172 SUPERFAMILY SSF55083 2 148 1.31E-39 T 06-07-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CAK77_RS02795 1f666dfc4fc7659c8469358cc744ae83 172 Gene3D G3DSA:3.30.70.560 2 155 2.2E-42 T 06-07-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CAK77_RS02795 1f666dfc4fc7659c8469358cc744ae83 172 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 82 93 - T 06-07-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CAK77_RS16820 db86138a76e32a6576e2d0ee76d3e5c8 264 Gene3D G3DSA:1.10.12.10 204 253 3.1E-14 T 06-07-2017 IPR014748 Crontonase, C-terminal CAK77_RS16820 db86138a76e32a6576e2d0ee76d3e5c8 264 Pfam PF00378 Enoyl-CoA hydratase/isomerase 17 253 1.1E-57 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAK77_RS16820 db86138a76e32a6576e2d0ee76d3e5c8 264 SUPERFAMILY SSF52096 14 254 6.91E-72 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS16820 db86138a76e32a6576e2d0ee76d3e5c8 264 Gene3D G3DSA:3.90.226.10 14 200 1.9E-59 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS05740 8dc4bb648b8b0d9358c8e90b09e164e6 350 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 106 178 4.1E-24 T 06-07-2017 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core CAK77_RS05740 8dc4bb648b8b0d9358c8e90b09e164e6 350 SUPERFAMILY SSF101386 90 182 1.29E-18 T 06-07-2017 CAK77_RS05740 8dc4bb648b8b0d9358c8e90b09e164e6 350 Gene3D G3DSA:1.10.287.1080 89 152 1.2E-9 T 06-07-2017 CAK77_RS22335 071c3514aa36f1f23a4dc14199203958 448 ProSitePatterns PS00217 Sugar transport proteins signature 2. 132 157 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CAK77_RS22335 071c3514aa36f1f23a4dc14199203958 448 Pfam PF00083 Sugar (and other) transporter 18 442 2.0E-33 T 06-07-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CAK77_RS22335 071c3514aa36f1f23a4dc14199203958 448 SUPERFAMILY SSF103473 12 441 2.22E-62 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK77_RS22335 071c3514aa36f1f23a4dc14199203958 448 Gene3D G3DSA:1.20.1250.20 249 434 6.8E-23 T 06-07-2017 CAK77_RS22335 071c3514aa36f1f23a4dc14199203958 448 Gene3D G3DSA:1.20.1250.20 16 228 6.0E-21 T 06-07-2017 CAK77_RS14680 807a8935db564560a1b6f25934f2a3b3 299 Pfam PF00106 short chain dehydrogenase 33 222 8.1E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS14680 807a8935db564560a1b6f25934f2a3b3 299 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 169 197 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK77_RS14680 807a8935db564560a1b6f25934f2a3b3 299 Gene3D G3DSA:3.40.50.720 29 246 2.1E-48 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS14680 807a8935db564560a1b6f25934f2a3b3 299 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 172 7.3E-16 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS14680 807a8935db564560a1b6f25934f2a3b3 299 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 203 220 7.3E-16 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS14680 807a8935db564560a1b6f25934f2a3b3 299 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 33 50 7.3E-16 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS14680 807a8935db564560a1b6f25934f2a3b3 299 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 107 118 7.3E-16 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS14680 807a8935db564560a1b6f25934f2a3b3 299 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 201 7.3E-16 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS14680 807a8935db564560a1b6f25934f2a3b3 299 SUPERFAMILY SSF51735 28 253 1.21E-48 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS18860 224bdc980c8c3abd4fa93ebe15252b8e 205 Gene3D G3DSA:2.60.120.10 3 195 9.5E-67 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK77_RS18860 224bdc980c8c3abd4fa93ebe15252b8e 205 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 4 203 4.0E-61 T 06-07-2017 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 CAK77_RS18860 224bdc980c8c3abd4fa93ebe15252b8e 205 SUPERFAMILY SSF51182 2 200 3.12E-67 T 06-07-2017 IPR011051 RmlC-like cupin domain CAK77_RS18860 224bdc980c8c3abd4fa93ebe15252b8e 205 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 6 181 5.0E-58 T 06-07-2017 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 CAK77_RS18540 69282339e4bc9d4f82ec04ba63778dc6 192 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 21 183 2.4E-26 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS18540 69282339e4bc9d4f82ec04ba63778dc6 192 SUPERFAMILY SSF88659 103 185 5.79E-17 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS18540 69282339e4bc9d4f82ec04ba63778dc6 192 Gene3D G3DSA:1.10.1740.10 8 121 1.7E-19 T 06-07-2017 CAK77_RS18540 69282339e4bc9d4f82ec04ba63778dc6 192 SUPERFAMILY SSF88946 7 112 3.45E-17 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS18540 69282339e4bc9d4f82ec04ba63778dc6 192 Pfam PF08281 Sigma-70, region 4 128 180 1.2E-12 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS18540 69282339e4bc9d4f82ec04ba63778dc6 192 Gene3D G3DSA:1.10.10.10 123 185 3.4E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS18540 69282339e4bc9d4f82ec04ba63778dc6 192 Pfam PF04542 Sigma-70 region 2 28 95 5.7E-12 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS19000 38394f0c483adec78544375d7435856e 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 26.675 T 06-07-2017 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CAK77_RS19000 38394f0c483adec78544375d7435856e 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 5.3E-57 T 06-07-2017 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 CAK77_RS19000 38394f0c483adec78544375d7435856e 122 Gene3D G3DSA:2.40.150.20 2 122 4.9E-53 T 06-07-2017 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CAK77_RS19000 38394f0c483adec78544375d7435856e 122 SMART SM01374 1 122 6.1E-86 T 06-07-2017 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CAK77_RS19000 38394f0c483adec78544375d7435856e 122 SUPERFAMILY SSF50193 2 122 5.63E-50 T 06-07-2017 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CAK77_RS19000 38394f0c483adec78544375d7435856e 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 06-07-2017 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK77_RS19000 38394f0c483adec78544375d7435856e 122 Pfam PF00238 Ribosomal protein L14p/L23e 2 122 5.8E-54 T 06-07-2017 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CAK77_RS22825 70eccca4e9c4718bdddce4e3f412d6d3 302 SUPERFAMILY SSF53335 15 279 3.07E-67 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS22825 70eccca4e9c4718bdddce4e3f412d6d3 302 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 17 276 2.0E-80 T 06-07-2017 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 CAK77_RS22825 70eccca4e9c4718bdddce4e3f412d6d3 302 Gene3D G3DSA:3.40.50.150 13 201 1.4E-15 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS22825 70eccca4e9c4718bdddce4e3f412d6d3 302 Pfam PF04072 Leucine carboxyl methyltransferase 19 194 2.6E-56 T 06-07-2017 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 CAK77_RS21985 15e4c3f09a53d59f821ab763bc08049b 195 PIRSF PIRSF000239 2 194 3.3E-49 T 06-07-2017 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CAK77_RS21985 15e4c3f09a53d59f821ab763bc08049b 195 Gene3D G3DSA:3.30.1020.10 164 185 8.1E-5 T 06-07-2017 CAK77_RS21985 15e4c3f09a53d59f821ab763bc08049b 195 Gene3D G3DSA:3.40.30.10 5 163 7.5E-57 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK77_RS21985 15e4c3f09a53d59f821ab763bc08049b 195 Pfam PF00578 AhpC/TSA family 25 146 5.6E-32 T 06-07-2017 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CAK77_RS21985 15e4c3f09a53d59f821ab763bc08049b 195 SUPERFAMILY SSF52833 6 188 2.24E-52 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK77_RS12760 a97d007d19d566882c087f56a017404a 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 31 54 1.3E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS12760 a97d007d19d566882c087f56a017404a 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 1.3E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS12760 a97d007d19d566882c087f56a017404a 192 SUPERFAMILY SSF48498 87 164 1.22E-7 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS12760 a97d007d19d566882c087f56a017404a 192 SUPERFAMILY SSF46689 4 75 6.16E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS12760 a97d007d19d566882c087f56a017404a 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 53 1.8E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS12760 a97d007d19d566882c087f56a017404a 192 Gene3D G3DSA:1.10.357.10 8 182 9.7E-26 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS10965 0f6f206eb7d003d4869cdfb7f7ef40a3 429 Gene3D G3DSA:3.50.50.60 6 203 5.5E-12 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS10965 0f6f206eb7d003d4869cdfb7f7ef40a3 429 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 90 284 5.6E-13 T 06-07-2017 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase CAK77_RS10965 0f6f206eb7d003d4869cdfb7f7ef40a3 429 Gene3D G3DSA:3.40.50.720 296 335 2.3E-4 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS10965 0f6f206eb7d003d4869cdfb7f7ef40a3 429 Gene3D G3DSA:3.40.50.720 204 233 2.3E-4 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS10965 0f6f206eb7d003d4869cdfb7f7ef40a3 429 SUPERFAMILY SSF51905 74 238 2.2E-12 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS10965 0f6f206eb7d003d4869cdfb7f7ef40a3 429 SUPERFAMILY SSF51905 5 39 2.2E-12 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS02300 c544bc7ca0aee1ec6769560b1c9ffbec 281 Pfam PF00892 EamA-like transporter family 147 276 2.6E-10 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAK77_RS02300 c544bc7ca0aee1ec6769560b1c9ffbec 281 SUPERFAMILY SSF103481 205 278 6.67E-12 T 06-07-2017 CAK77_RS12685 9db09e571b5472e8b3e77c3f9b735fde 283 SUPERFAMILY SSF53850 122 269 1.48E-12 T 06-07-2017 CAK77_RS12685 9db09e571b5472e8b3e77c3f9b735fde 283 Gene3D G3DSA:3.40.190.10 19 193 2.4E-10 T 06-07-2017 CAK77_RS19555 848b65c19ff1f55bc3f143517a260ce1 100 Gene3D G3DSA:1.10.287.1060 6 95 1.1E-6 T 06-07-2017 CAK77_RS19555 848b65c19ff1f55bc3f143517a260ce1 100 SUPERFAMILY SSF140453 5 96 1.96E-8 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like CAK77_RS07980 848b65c19ff1f55bc3f143517a260ce1 100 Gene3D G3DSA:1.10.287.1060 6 95 1.1E-6 T 06-07-2017 CAK77_RS07980 848b65c19ff1f55bc3f143517a260ce1 100 SUPERFAMILY SSF140453 5 96 1.96E-8 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like CAK77_RS11615 6450f3e1fc691bc546070f0800876aea 238 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 47 1.1E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS11615 6450f3e1fc691bc546070f0800876aea 238 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 55 78 1.1E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS11615 6450f3e1fc691bc546070f0800876aea 238 SUPERFAMILY SSF46689 21 89 3.79E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS11615 6450f3e1fc691bc546070f0800876aea 238 Pfam PF00440 Bacterial regulatory proteins, tetR family 34 78 6.6E-14 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS11615 6450f3e1fc691bc546070f0800876aea 238 Gene3D G3DSA:1.10.357.10 18 205 9.9E-24 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS01875 57ae8ccacf6d0f8b68a1864600269eee 322 PIRSF PIRSF018005 6 322 6.7E-133 T 06-07-2017 IPR017804 Methyltransferase EgtD-like CAK77_RS01875 57ae8ccacf6d0f8b68a1864600269eee 322 Gene3D G3DSA:3.40.50.150 52 147 1.0E-4 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS01875 57ae8ccacf6d0f8b68a1864600269eee 322 Pfam PF10017 Histidine-specific methyltransferase, SAM-dependent 192 316 9.5E-43 T 06-07-2017 IPR019257 Histidine-specific methyltransferase, SAM-dependent CAK77_RS01875 57ae8ccacf6d0f8b68a1864600269eee 322 Hamap MF_02037 Histidine N-alpha-methyltransferase [egtD]. 9 321 52.788 T 06-07-2017 IPR032888 Histidine N-alpha-methyltransferase, Actinobacteria-type GO:0008276|GO:0052699 KEGG: 00340+2.1.1.44|MetaCyc: PWY-7255|MetaCyc: PWY-7550 CAK77_RS01875 57ae8ccacf6d0f8b68a1864600269eee 322 SUPERFAMILY SSF53335 36 194 5.64E-9 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS01875 57ae8ccacf6d0f8b68a1864600269eee 322 SUPERFAMILY SSF53335 284 316 5.64E-9 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS01875 57ae8ccacf6d0f8b68a1864600269eee 322 TIGRFAM TIGR03438 egtD_ergothio: dimethylhistidine N-methyltransferase 22 318 2.0E-113 T 06-07-2017 IPR017804 Methyltransferase EgtD-like CAK77_RS23135 3908491387a1a766c57da18b45b6a732 212 ProSitePatterns PS01081 TetR-type HTH domain signature. 28 58 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CAK77_RS23135 3908491387a1a766c57da18b45b6a732 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 1.2E-14 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS23135 3908491387a1a766c57da18b45b6a732 212 Gene3D G3DSA:1.10.357.10 1 194 2.0E-29 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS23135 3908491387a1a766c57da18b45b6a732 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 3.3E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS23135 3908491387a1a766c57da18b45b6a732 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 3.3E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS23135 3908491387a1a766c57da18b45b6a732 212 SUPERFAMILY SSF46689 2 76 5.64E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS04290 86902d742849b3d49c25442c21bb672f 360 ProSitePatterns PS01174 Lipolytic enzymes "G-D-X-G" family, putative serine active site. 185 197 - T 06-07-2017 IPR033140 Lipase, GDXG, putative serine active site CAK77_RS04290 86902d742849b3d49c25442c21bb672f 360 SUPERFAMILY SSF53474 79 339 1.96E-50 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS04290 86902d742849b3d49c25442c21bb672f 360 Gene3D G3DSA:3.40.50.1820 109 339 7.8E-56 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS04290 86902d742849b3d49c25442c21bb672f 360 Pfam PF07859 alpha/beta hydrolase fold 117 318 8.8E-46 T 06-07-2017 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CAK77_RS21900 2a0c0015b949bad38bffa04ba4e91a02 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 7.4E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS21900 2a0c0015b949bad38bffa04ba4e91a02 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 7.4E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS21900 2a0c0015b949bad38bffa04ba4e91a02 196 SUPERFAMILY SSF48498 78 194 2.89E-14 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS21900 2a0c0015b949bad38bffa04ba4e91a02 196 Gene3D G3DSA:1.10.357.10 11 192 8.6E-25 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS21900 2a0c0015b949bad38bffa04ba4e91a02 196 SUPERFAMILY SSF46689 4 73 8.21E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS21900 2a0c0015b949bad38bffa04ba4e91a02 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 61 2.3E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS03635 3cf87c02eacd4cac55fece8bac5dac99 272 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 15 155 9.9E-29 T 06-07-2017 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 CAK77_RS03635 3cf87c02eacd4cac55fece8bac5dac99 272 Gene3D G3DSA:1.20.120.450 6 132 4.6E-15 T 06-07-2017 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase CAK77_RS03635 3cf87c02eacd4cac55fece8bac5dac99 272 SUPERFAMILY SSF109854 4 161 5.95E-35 T 06-07-2017 CAK77_RS03635 3cf87c02eacd4cac55fece8bac5dac99 272 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 15 244 3.1E-37 T 06-07-2017 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type CAK77_RS13560 4b6949fcb67e273d9b88f3bc9fe10479 78 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 3 70 5.8E-19 T 06-07-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CAK77_RS13560 4b6949fcb67e273d9b88f3bc9fe10479 78 Pfam PF03840 Preprotein translocase SecG subunit 5 71 4.6E-16 T 06-07-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CAK77_RS18315 c82a49af98dfd5f20cb67efaa84f63fa 199 SUPERFAMILY SSF69118 4 178 1.41E-38 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAK77_RS18315 c82a49af98dfd5f20cb67efaa84f63fa 199 Gene3D G3DSA:1.20.1290.10 34 180 1.6E-34 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAK77_RS00795 d233fbed7fc31206fa0f15bf8f5248cc 181 Pfam PF00210 Ferritin-like domain 13 148 8.7E-35 T 06-07-2017 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 CAK77_RS00795 d233fbed7fc31206fa0f15bf8f5248cc 181 Gene3D G3DSA:1.20.1260.10 8 154 3.7E-45 T 06-07-2017 IPR012347 Ferritin-related CAK77_RS00795 d233fbed7fc31206fa0f15bf8f5248cc 181 SUPERFAMILY SSF47240 9 154 3.87E-45 T 06-07-2017 IPR009078 Ferritin-like superfamily CAK77_RS01915 4f0469a653ec620d2fba488ff1c7c612 292 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 158 186 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK77_RS01915 4f0469a653ec620d2fba488ff1c7c612 292 Gene3D G3DSA:3.40.50.720 1 265 1.5E-60 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS01915 4f0469a653ec620d2fba488ff1c7c612 292 Pfam PF00106 short chain dehydrogenase 8 201 1.5E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS01915 4f0469a653ec620d2fba488ff1c7c612 292 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 160 1.6E-20 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS01915 4f0469a653ec620d2fba488ff1c7c612 292 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 190 1.6E-20 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS01915 4f0469a653ec620d2fba488ff1c7c612 292 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 192 209 1.6E-20 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS01915 4f0469a653ec620d2fba488ff1c7c612 292 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.6E-20 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS01915 4f0469a653ec620d2fba488ff1c7c612 292 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 225 245 1.6E-20 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS01915 4f0469a653ec620d2fba488ff1c7c612 292 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 91 102 1.6E-20 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS01915 4f0469a653ec620d2fba488ff1c7c612 292 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 205 0.0013 T 06-07-2017 CAK77_RS01915 4f0469a653ec620d2fba488ff1c7c612 292 SUPERFAMILY SSF51735 2 261 2.76E-56 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS01915 4f0469a653ec620d2fba488ff1c7c612 292 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 91 102 8.0E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS01915 4f0469a653ec620d2fba488ff1c7c612 292 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 171 190 8.0E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS01915 4f0469a653ec620d2fba488ff1c7c612 292 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 158 8.0E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06005 c01c623d9e8f9d29227de587891c3b20 190 Pfam PF06271 RDD family 35 183 4.4E-21 T 06-07-2017 IPR010432 RDD CAK77_RS22140 f4122b1f887f5561284caea644ac681f 227 Pfam PF07099 Protein of unknown function (DUF1361) 41 186 8.2E-39 T 06-07-2017 IPR009793 Protein of unknown function DUF1361 CAK77_RS21635 53f72ea74ec7b762fba8882da116d858 299 Gene3D G3DSA:3.40.50.1820 11 295 3.4E-51 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS21635 53f72ea74ec7b762fba8882da116d858 299 SUPERFAMILY SSF53474 7 297 1.06E-50 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS21635 53f72ea74ec7b762fba8882da116d858 299 Pfam PF00561 alpha/beta hydrolase fold 31 118 1.2E-14 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS09155 f5717fd9a5abf8ba717b8dad4646abbe 214 Pfam PF10738 Probable lipoprotein LpqN 59 209 1.9E-9 T 06-07-2017 IPR019674 Lipoprotein LpqT, predicted CAK77_RS03525 883aa1922cd77f42171e3a7715d1a249 592 Gene3D G3DSA:3.20.20.140 74 315 1.1E-74 T 06-07-2017 CAK77_RS03525 883aa1922cd77f42171e3a7715d1a249 592 Gene3D G3DSA:3.20.20.140 428 491 1.1E-74 T 06-07-2017 CAK77_RS03525 883aa1922cd77f42171e3a7715d1a249 592 SUPERFAMILY SSF51556 372 503 1.78E-38 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK77_RS03525 883aa1922cd77f42171e3a7715d1a249 592 SUPERFAMILY SSF51556 60 323 1.78E-38 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK77_RS03525 883aa1922cd77f42171e3a7715d1a249 592 Pfam PF07969 Amidohydrolase family 48 105 5.1E-8 T 06-07-2017 IPR013108 Amidohydrolase 3 CAK77_RS03525 883aa1922cd77f42171e3a7715d1a249 592 Gene3D G3DSA:2.30.40.10 492 583 8.7E-13 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK77_RS03525 883aa1922cd77f42171e3a7715d1a249 592 Gene3D G3DSA:2.30.40.10 4 73 1.1E-16 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK77_RS03525 883aa1922cd77f42171e3a7715d1a249 592 SUPERFAMILY SSF51338 506 573 2.3E-18 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK77_RS03525 883aa1922cd77f42171e3a7715d1a249 592 SUPERFAMILY SSF51338 4 59 2.3E-18 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK77_RS00915 9684e1b99003b293f7ef388b6275994b 116 SUPERFAMILY SSF55486 4 115 4.01E-38 T 06-07-2017 CAK77_RS00915 9684e1b99003b293f7ef388b6275994b 116 Pfam PF06262 Zinicin-like metallopeptidase 29 115 1.1E-33 T 06-07-2017 IPR010428 Zinicin-like metallopeptidase CAK77_RS11515 86acf8c468558d881e99c5aa22ed8106 214 Pfam PF00293 NUDIX domain 53 163 7.7E-14 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 CAK77_RS11515 86acf8c468558d881e99c5aa22ed8106 214 Gene3D G3DSA:3.90.79.10 16 184 2.1E-51 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAK77_RS11515 86acf8c468558d881e99c5aa22ed8106 214 SUPERFAMILY SSF55811 15 184 1.11E-44 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAK77_RS19765 ed14bfaf0af7cb3232e949af34e41265 295 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 43 187 0.0064 T 06-07-2017 CAK77_RS19765 ed14bfaf0af7cb3232e949af34e41265 295 Gene3D G3DSA:3.40.50.720 39 258 3.6E-56 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS19765 ed14bfaf0af7cb3232e949af34e41265 295 SUPERFAMILY SSF51735 39 257 1.46E-56 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS19765 ed14bfaf0af7cb3232e949af34e41265 295 Pfam PF00106 short chain dehydrogenase 43 235 1.8E-46 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS19765 ed14bfaf0af7cb3232e949af34e41265 295 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 173 181 1.5E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS19765 ed14bfaf0af7cb3232e949af34e41265 295 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 118 129 1.5E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS19765 ed14bfaf0af7cb3232e949af34e41265 295 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 194 213 1.5E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS19765 ed14bfaf0af7cb3232e949af34e41265 295 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 118 129 7.7E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS19765 ed14bfaf0af7cb3232e949af34e41265 295 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 183 7.7E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS19765 ed14bfaf0af7cb3232e949af34e41265 295 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 44 61 7.7E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS19765 ed14bfaf0af7cb3232e949af34e41265 295 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 194 213 7.7E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS20640 5faa52bd59d20eea0d3e6df70b53ac85 476 Pfam PF06114 Domain of unknown function (DUF955) 189 310 1.4E-24 T 06-07-2017 IPR010359 HTH domain, IrrE-type CAK77_RS20640 5faa52bd59d20eea0d3e6df70b53ac85 476 Pfam PF12844 Helix-turn-helix domain 7 65 3.2E-12 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAK77_RS20640 5faa52bd59d20eea0d3e6df70b53ac85 476 PIRSF PIRSF019251 1 472 2.6E-201 T 06-07-2017 IPR026281 HTH-type transcriptional regulator RamB GO:0006355 CAK77_RS20640 5faa52bd59d20eea0d3e6df70b53ac85 476 Gene3D G3DSA:1.10.260.40 4 74 6.4E-18 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK77_RS20640 5faa52bd59d20eea0d3e6df70b53ac85 476 SMART SM00530 9 64 5.0E-14 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAK77_RS20640 5faa52bd59d20eea0d3e6df70b53ac85 476 SUPERFAMILY SSF47413 4 68 9.38E-15 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK77_RS20640 5faa52bd59d20eea0d3e6df70b53ac85 476 Pfam PF09856 Predicted transcriptional regulator (DUF2083) 311 467 1.4E-71 T 06-07-2017 IPR018653 Domain of unknown function DUF2083,transcriptional regulator CAK77_RS21675 6c08b858c4d6ea477899d97b4c7b5f39 484 Gene3D G3DSA:2.40.10.10 270 399 4.7E-42 T 06-07-2017 CAK77_RS21675 6c08b858c4d6ea477899d97b4c7b5f39 484 SUPERFAMILY SSF50494 222 404 1.1E-52 T 06-07-2017 IPR009003 Peptidase S1, PA clan CAK77_RS21675 6c08b858c4d6ea477899d97b4c7b5f39 484 SUPERFAMILY SSF50494 115 179 1.1E-52 T 06-07-2017 IPR009003 Peptidase S1, PA clan CAK77_RS21675 6c08b858c4d6ea477899d97b4c7b5f39 484 Pfam PF13365 Trypsin-like peptidase domain 147 348 1.4E-31 T 06-07-2017 CAK77_RS21675 6c08b858c4d6ea477899d97b4c7b5f39 484 SUPERFAMILY SSF50156 396 481 1.71E-16 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAK77_RS21675 6c08b858c4d6ea477899d97b4c7b5f39 484 PRINTS PR00834 HtrA/DegQ protease family signature 427 439 2.1E-22 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAK77_RS21675 6c08b858c4d6ea477899d97b4c7b5f39 484 PRINTS PR00834 HtrA/DegQ protease family signature 319 336 2.1E-22 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAK77_RS21675 6c08b858c4d6ea477899d97b4c7b5f39 484 PRINTS PR00834 HtrA/DegQ protease family signature 341 358 2.1E-22 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAK77_RS21675 6c08b858c4d6ea477899d97b4c7b5f39 484 PRINTS PR00834 HtrA/DegQ protease family signature 156 168 2.1E-22 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAK77_RS21675 6c08b858c4d6ea477899d97b4c7b5f39 484 Gene3D G3DSA:2.30.42.10 400 482 1.4E-16 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAK77_RS21675 6c08b858c4d6ea477899d97b4c7b5f39 484 Pfam PF13180 PDZ domain 398 479 3.8E-12 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAK77_RS21675 6c08b858c4d6ea477899d97b4c7b5f39 484 Gene3D G3DSA:2.40.10.10 120 178 1.3E-28 T 06-07-2017 CAK77_RS21675 6c08b858c4d6ea477899d97b4c7b5f39 484 Gene3D G3DSA:2.40.10.10 230 265 1.3E-28 T 06-07-2017 CAK77_RS21675 6c08b858c4d6ea477899d97b4c7b5f39 484 SMART SM00228 397 469 8.0E-10 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAK77_RS16760 402bf4eee996b00d5aace6108b4bb371 107 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 9 103 5.1E-13 T 06-07-2017 IPR008407 Branched-chain amino acid transport, AzlD CAK77_RS16760 402bf4eee996b00d5aace6108b4bb371 107 PIRSF PIRSF003203 1 107 1.0E-25 T 06-07-2017 IPR008407 Branched-chain amino acid transport, AzlD CAK77_RS02855 a4dae28808bf6f8d9c3912e7f969e233 350 Gene3D G3DSA:1.10.3470.10 8 343 1.1E-98 T 06-07-2017 IPR029022 ABC transporter, BtuC-like CAK77_RS02855 a4dae28808bf6f8d9c3912e7f969e233 350 SUPERFAMILY SSF81345 7 342 1.29E-76 T 06-07-2017 IPR029022 ABC transporter, BtuC-like CAK77_RS02855 a4dae28808bf6f8d9c3912e7f969e233 350 Pfam PF01032 FecCD transport family 21 341 4.1E-91 T 06-07-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CAK77_RS19040 ecadd094aab264b1b3fb4072b6dd47ea 156 ProSitePatterns PS00464 Ribosomal protein L22 signature. 90 114 - T 06-07-2017 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK77_RS19040 ecadd094aab264b1b3fb4072b6dd47ea 156 Gene3D G3DSA:3.90.470.10 10 118 1.0E-43 T 06-07-2017 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 CAK77_RS19040 ecadd094aab264b1b3fb4072b6dd47ea 156 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 12 114 2.3E-50 T 06-07-2017 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS19040 ecadd094aab264b1b3fb4072b6dd47ea 156 SUPERFAMILY SSF54843 8 118 1.96E-42 T 06-07-2017 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 CAK77_RS19040 ecadd094aab264b1b3fb4072b6dd47ea 156 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 8 117 29.132 T 06-07-2017 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS19040 ecadd094aab264b1b3fb4072b6dd47ea 156 Pfam PF00237 Ribosomal protein L22p/L17e 15 115 9.6E-32 T 06-07-2017 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 CAK77_RS02685 b1e4f3d0db4bd337cf5378f43c777565 321 Pfam PF00106 short chain dehydrogenase 12 197 2.9E-53 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS02685 b1e4f3d0db4bd337cf5378f43c777565 321 SUPERFAMILY SSF51735 11 252 3.45E-67 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS02685 b1e4f3d0db4bd337cf5378f43c777565 321 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 146 174 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK77_RS02685 b1e4f3d0db4bd337cf5378f43c777565 321 Gene3D G3DSA:3.40.50.720 12 250 5.2E-71 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS02685 b1e4f3d0db4bd337cf5378f43c777565 321 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 8.0E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS02685 b1e4f3d0db4bd337cf5378f43c777565 321 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 8.0E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS02685 b1e4f3d0db4bd337cf5378f43c777565 321 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 8.0E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS02685 b1e4f3d0db4bd337cf5378f43c777565 321 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 8.1E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS02685 b1e4f3d0db4bd337cf5378f43c777565 321 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 8.1E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS02685 b1e4f3d0db4bd337cf5378f43c777565 321 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 8.1E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS02685 b1e4f3d0db4bd337cf5378f43c777565 321 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 8.1E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS02685 b1e4f3d0db4bd337cf5378f43c777565 321 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 8.1E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS00655 f3c5b824295c0abfd554b4fb15a7fd61 520 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 10 225 5.1E-17 T 06-07-2017 CAK77_RS00655 f3c5b824295c0abfd554b4fb15a7fd61 520 Gene3D G3DSA:3.50.50.60 329 496 1.8E-6 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS00655 f3c5b824295c0abfd554b4fb15a7fd61 520 Gene3D G3DSA:3.50.50.60 2 209 8.3E-57 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS00655 f3c5b824295c0abfd554b4fb15a7fd61 520 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 174 192 9.8E-9 T 06-07-2017 CAK77_RS00655 f3c5b824295c0abfd554b4fb15a7fd61 520 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 9.8E-9 T 06-07-2017 CAK77_RS00655 f3c5b824295c0abfd554b4fb15a7fd61 520 SUPERFAMILY SSF51905 274 476 1.89E-10 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS00655 f3c5b824295c0abfd554b4fb15a7fd61 520 SUPERFAMILY SSF51905 6 216 4.12E-51 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS00655 f3c5b824295c0abfd554b4fb15a7fd61 520 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 170 194 8.8E-11 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAK77_RS00655 f3c5b824295c0abfd554b4fb15a7fd61 520 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 7 29 8.8E-11 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAK77_RS21740 682c4b85a837138783900f8a5dbb2840 239 Pfam PF00440 Bacterial regulatory proteins, tetR family 28 74 6.3E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS21740 682c4b85a837138783900f8a5dbb2840 239 SUPERFAMILY SSF46689 22 80 3.89E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS21740 682c4b85a837138783900f8a5dbb2840 239 PRINTS PR00400 Tetracycline repressor protein signature 149 168 1.6E-5 T 06-07-2017 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 CAK77_RS21740 682c4b85a837138783900f8a5dbb2840 239 PRINTS PR00400 Tetracycline repressor protein signature 40 63 1.6E-5 T 06-07-2017 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 CAK77_RS21740 682c4b85a837138783900f8a5dbb2840 239 PRINTS PR00400 Tetracycline repressor protein signature 205 219 1.6E-5 T 06-07-2017 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 CAK77_RS21740 682c4b85a837138783900f8a5dbb2840 239 Gene3D G3DSA:1.10.357.10 13 221 2.6E-43 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS21740 682c4b85a837138783900f8a5dbb2840 239 SUPERFAMILY SSF48498 93 224 2.45E-17 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS19390 70421389f76b79521b70d619a3eec50f 530 Gene3D G3DSA:3.30.465.10 160 276 3.3E-17 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAK77_RS19390 70421389f76b79521b70d619a3eec50f 530 Gene3D G3DSA:1.10.45.10 487 525 5.2E-10 T 06-07-2017 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 CAK77_RS19390 70421389f76b79521b70d619a3eec50f 530 Gene3D G3DSA:3.30.43.10 48 155 1.3E-20 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CAK77_RS19390 70421389f76b79521b70d619a3eec50f 530 SUPERFAMILY SSF56176 54 276 3.69E-45 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAK77_RS19390 70421389f76b79521b70d619a3eec50f 530 Pfam PF01565 FAD binding domain 98 237 7.5E-31 T 06-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CAK77_RS19390 70421389f76b79521b70d619a3eec50f 530 SUPERFAMILY SSF55103 281 527 1.28E-42 T 06-07-2017 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CAK77_RS19390 70421389f76b79521b70d619a3eec50f 530 Pfam PF02913 FAD linked oxidases, C-terminal domain 276 525 1.2E-45 T 06-07-2017 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 CAK77_RS14005 840421b6045551b3f1c2befd1fecf138 225 Pfam PF13419 Haloacid dehalogenase-like hydrolase 7 194 2.2E-11 T 06-07-2017 IPR023214 HAD-like domain CAK77_RS14005 840421b6045551b3f1c2befd1fecf138 225 Gene3D G3DSA:3.40.50.1000 3 210 1.3E-33 T 06-07-2017 IPR023214 HAD-like domain CAK77_RS14005 840421b6045551b3f1c2befd1fecf138 225 SUPERFAMILY SSF56784 3 204 1.62E-40 T 06-07-2017 IPR023214 HAD-like domain CAK77_RS14005 840421b6045551b3f1c2befd1fecf138 225 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 3 14 1.6E-10 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAK77_RS14005 840421b6045551b3f1c2befd1fecf138 225 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 183 196 1.6E-10 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAK77_RS14005 840421b6045551b3f1c2befd1fecf138 225 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 138 154 1.6E-10 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAK77_RS14005 840421b6045551b3f1c2befd1fecf138 225 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 156 176 1.6E-10 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAK77_RS14005 840421b6045551b3f1c2befd1fecf138 225 TIGRFAM TIGR01428 HAD_type_II: haloacid dehalogenase, type II 4 199 1.0E-48 T 06-07-2017 IPR006328 Haloacid dehalogenase, type II GO:0008152|GO:0019120 KEGG: 00361+3.8.1.2|KEGG: 00625+3.8.1.2|MetaCyc: PWY-7425 CAK77_RS14005 840421b6045551b3f1c2befd1fecf138 225 TIGRFAM TIGR01493 HAD-SF-IA-v2: HAD hydrolase, family IA, variant 2 5 186 1.6E-22 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAK77_RS08515 a1fc1b0203b588796a3f0f89136617b8 123 SUPERFAMILY SSF53927 22 93 5.27E-11 T 06-07-2017 IPR016193 Cytidine deaminase-like GO:0003824 CAK77_RS08515 a1fc1b0203b588796a3f0f89136617b8 123 Gene3D G3DSA:3.40.140.10 18 93 5.1E-7 T 06-07-2017 CAK77_RS10745 d8c307c6d98ae417cdf94197836b9788 601 Gene3D G3DSA:3.60.110.10 285 548 6.8E-33 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAK77_RS10745 d8c307c6d98ae417cdf94197836b9788 601 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 65 564 14.591 T 06-07-2017 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 CAK77_RS10745 d8c307c6d98ae417cdf94197836b9788 601 Pfam PF00795 Carbon-nitrogen hydrolase 291 543 2.1E-16 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAK77_RS10745 d8c307c6d98ae417cdf94197836b9788 601 SUPERFAMILY SSF56317 287 558 4.32E-41 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAK77_RS10745 d8c307c6d98ae417cdf94197836b9788 601 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 120 525 7.4E-85 T 06-07-2017 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 CAK77_RS17395 277fb53c15652019763f1f2dbcfb35f6 159 Gene3D G3DSA:2.40.280.10 10 130 3.6E-48 T 06-07-2017 IPR023620 Small protein B CAK77_RS17395 277fb53c15652019763f1f2dbcfb35f6 159 Pfam PF01668 SmpB protein 11 74 6.3E-28 T 06-07-2017 IPR000037 SsrA-binding protein GO:0003723 CAK77_RS17395 277fb53c15652019763f1f2dbcfb35f6 159 TIGRFAM TIGR00086 smpB: SsrA-binding protein 11 152 4.2E-55 T 06-07-2017 IPR000037 SsrA-binding protein GO:0003723 CAK77_RS17395 277fb53c15652019763f1f2dbcfb35f6 159 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 12 135 2.0E-54 T 06-07-2017 IPR000037 SsrA-binding protein GO:0003723 CAK77_RS17395 277fb53c15652019763f1f2dbcfb35f6 159 SUPERFAMILY SSF74982 7 135 2.62E-49 T 06-07-2017 IPR023620 Small protein B CAK77_RS17395 277fb53c15652019763f1f2dbcfb35f6 159 Hamap MF_00023 SsrA-binding protein [smpB]. 1 158 68.671 T 06-07-2017 IPR000037 SsrA-binding protein GO:0003723 CAK77_RS14970 396ff93fedb03efa369cc62a5f493621 286 Pfam PF00459 Inositol monophosphatase family 9 253 2.5E-59 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAK77_RS14970 396ff93fedb03efa369cc62a5f493621 286 PRINTS PR00377 Inositol monophosphatase superfamily signature 66 82 5.0E-32 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAK77_RS14970 396ff93fedb03efa369cc62a5f493621 286 PRINTS PR00377 Inositol monophosphatase superfamily signature 44 64 5.0E-32 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAK77_RS14970 396ff93fedb03efa369cc62a5f493621 286 PRINTS PR00377 Inositol monophosphatase superfamily signature 195 216 5.0E-32 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAK77_RS14970 396ff93fedb03efa369cc62a5f493621 286 PRINTS PR00377 Inositol monophosphatase superfamily signature 95 111 5.0E-32 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAK77_RS14970 396ff93fedb03efa369cc62a5f493621 286 PRINTS PR00377 Inositol monophosphatase superfamily signature 226 250 5.0E-32 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAK77_RS14970 396ff93fedb03efa369cc62a5f493621 286 Gene3D G3DSA:3.30.540.10 8 170 4.1E-43 T 06-07-2017 CAK77_RS14970 396ff93fedb03efa369cc62a5f493621 286 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 229 243 - T 06-07-2017 IPR020550 Inositol monophosphatase, conserved site GO:0046854 CAK77_RS14970 396ff93fedb03efa369cc62a5f493621 286 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 95 108 - T 06-07-2017 IPR020583 Inositol monophosphatase, metal-binding site CAK77_RS14970 396ff93fedb03efa369cc62a5f493621 286 SUPERFAMILY SSF56655 8 275 9.16E-67 T 06-07-2017 CAK77_RS14970 396ff93fedb03efa369cc62a5f493621 286 Gene3D G3DSA:3.40.190.80 171 277 3.6E-29 T 06-07-2017 CAK77_RS09335 e5e9c21327820e3365a713d2d8ff1c90 236 SUPERFAMILY SSF52172 8 187 1.81E-40 T 06-07-2017 IPR011006 CheY-like superfamily CAK77_RS09335 e5e9c21327820e3365a713d2d8ff1c90 236 SMART SM00448 9 120 8.8E-40 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK77_RS09335 e5e9c21327820e3365a713d2d8ff1c90 236 Pfam PF00486 Transcriptional regulatory protein, C terminal 157 232 4.5E-25 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAK77_RS09335 e5e9c21327820e3365a713d2d8ff1c90 236 Gene3D G3DSA:3.40.50.2300 6 128 2.4E-40 T 06-07-2017 CAK77_RS09335 e5e9c21327820e3365a713d2d8ff1c90 236 SMART SM00862 157 232 3.6E-26 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAK77_RS09335 e5e9c21327820e3365a713d2d8ff1c90 236 Pfam PF00072 Response regulator receiver domain 11 120 1.2E-28 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK77_RS09335 e5e9c21327820e3365a713d2d8ff1c90 236 Gene3D G3DSA:1.10.10.10 135 234 6.8E-33 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS14600 f41acbb4ef7e8d5241314f265563e6e2 456 Pfam PF01979 Amidohydrolase family 62 405 4.3E-63 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAK77_RS14600 f41acbb4ef7e8d5241314f265563e6e2 456 Gene3D G3DSA:3.20.20.140 67 386 7.4E-107 T 06-07-2017 CAK77_RS14600 f41acbb4ef7e8d5241314f265563e6e2 456 SUPERFAMILY SSF51556 64 378 3.62E-95 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK77_RS14600 f41acbb4ef7e8d5241314f265563e6e2 456 SUPERFAMILY SSF51338 5 64 2.52E-22 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK77_RS14600 f41acbb4ef7e8d5241314f265563e6e2 456 SUPERFAMILY SSF51338 378 451 2.52E-22 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK77_RS14600 f41acbb4ef7e8d5241314f265563e6e2 456 Gene3D G3DSA:2.30.40.10 387 399 1.9E-13 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK77_RS14600 f41acbb4ef7e8d5241314f265563e6e2 456 Gene3D G3DSA:2.30.40.10 13 66 1.9E-13 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK77_RS23280 01897c007608648a41cfd7dbe2d7708a 34 Pfam PF03055 Retinal pigment epithelial membrane protein 1 31 1.9E-10 T 06-07-2017 IPR004294 Carotenoid oxygenase GO:0016702|GO:0055114 CAK77_RS03145 809e47efb7197343209167e050a5072d 260 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 136 164 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK77_RS03145 809e47efb7197343209167e050a5072d 260 SUPERFAMILY SSF51735 10 239 2.78E-72 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS03145 809e47efb7197343209167e050a5072d 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 5.2E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS03145 809e47efb7197343209167e050a5072d 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 204 224 5.2E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS03145 809e47efb7197343209167e050a5072d 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 139 5.2E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS03145 809e47efb7197343209167e050a5072d 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 5.2E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS03145 809e47efb7197343209167e050a5072d 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 5.2E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS03145 809e47efb7197343209167e050a5072d 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 168 5.2E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS03145 809e47efb7197343209167e050a5072d 260 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 20 239 1.2E-55 T 06-07-2017 CAK77_RS03145 809e47efb7197343209167e050a5072d 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 129 137 6.2E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS03145 809e47efb7197343209167e050a5072d 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 6.2E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS03145 809e47efb7197343209167e050a5072d 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 168 6.2E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS03145 809e47efb7197343209167e050a5072d 260 Gene3D G3DSA:3.40.50.720 8 239 4.5E-69 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS09035 e50d0232a483579588b282827f395d5c 102 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 40 81 3.0E-16 T 06-07-2017 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS09035 e50d0232a483579588b282827f395d5c 102 Pfam PF00550 Phosphopantetheine attachment site 14 79 2.3E-16 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS09035 e50d0232a483579588b282827f395d5c 102 SUPERFAMILY SSF47336 7 97 1.19E-23 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS09035 e50d0232a483579588b282827f395d5c 102 Gene3D G3DSA:1.10.1200.10 4 84 1.2E-25 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS09035 e50d0232a483579588b282827f395d5c 102 Hamap MF_01217 Acyl carrier protein [acpP]. 9 83 17.204 T 06-07-2017 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS07470 3e43e8f392601656c59239acdea84e80 206 Gene3D G3DSA:3.90.950.10 1 198 1.6E-77 T 06-07-2017 IPR029001 Inosine triphosphate pyrophosphatase-like CAK77_RS07470 3e43e8f392601656c59239acdea84e80 206 SUPERFAMILY SSF52972 1 197 1.41E-61 T 06-07-2017 IPR029001 Inosine triphosphate pyrophosphatase-like CAK77_RS07470 3e43e8f392601656c59239acdea84e80 206 Hamap MF_01405 dITP/XTP pyrophosphatase [rdgB]. 1 197 46.716 T 06-07-2017 IPR020922 Non-canonical purine NTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206 CAK77_RS07470 3e43e8f392601656c59239acdea84e80 206 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 2 195 5.4E-48 T 06-07-2017 IPR002637 Ham1-like protein GO:0016787 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206|Reactome: R-HSA-15869 CAK77_RS07470 3e43e8f392601656c59239acdea84e80 206 Pfam PF01725 Ham1 family 3 192 1.6E-51 T 06-07-2017 IPR002637 Ham1-like protein GO:0016787 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206|Reactome: R-HSA-15869 CAK77_RS15020 014ea37a1a3bb4547be20ee36e715525 128 SUPERFAMILY SSF55298 3 127 7.07E-35 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAK77_RS15020 014ea37a1a3bb4547be20ee36e715525 128 Pfam PF01042 Endoribonuclease L-PSP 13 126 1.6E-28 T 06-07-2017 IPR006175 YjgF/YER057c/UK114 family CAK77_RS15020 014ea37a1a3bb4547be20ee36e715525 128 Gene3D G3DSA:3.30.1330.40 5 128 1.9E-43 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAK77_RS17605 1ce8bdd09e852ca05beedbb68a534877 1078 SUPERFAMILY SSF52980 913 1033 3.11E-5 T 06-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CAK77_RS17605 1ce8bdd09e852ca05beedbb68a534877 1078 Gene3D G3DSA:3.40.50.300 17 169 1.6E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS17605 1ce8bdd09e852ca05beedbb68a534877 1078 Gene3D G3DSA:3.40.50.300 229 332 1.6E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS17605 1ce8bdd09e852ca05beedbb68a534877 1078 SUPERFAMILY SSF52540 219 497 4.58E-100 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS17605 1ce8bdd09e852ca05beedbb68a534877 1078 SUPERFAMILY SSF52540 15 186 4.58E-100 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS17605 1ce8bdd09e852ca05beedbb68a534877 1078 SUPERFAMILY SSF52540 527 681 4.58E-100 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS17605 1ce8bdd09e852ca05beedbb68a534877 1078 SUPERFAMILY SSF52540 735 781 4.58E-100 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS17605 1ce8bdd09e852ca05beedbb68a534877 1078 Pfam PF12705 PD-(D/E)XK nuclease superfamily 899 1055 1.6E-11 T 06-07-2017 CAK77_RS17605 1ce8bdd09e852ca05beedbb68a534877 1078 Pfam PF00580 UvrD/REP helicase N-terminal domain 19 331 5.8E-39 T 06-07-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 CAK77_RS17605 1ce8bdd09e852ca05beedbb68a534877 1078 Pfam PF13361 UvrD-like helicase C-terminal domain 355 491 4.7E-7 T 06-07-2017 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CAK77_RS17605 1ce8bdd09e852ca05beedbb68a534877 1078 Pfam PF13361 UvrD-like helicase C-terminal domain 642 757 4.0E-17 T 06-07-2017 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CAK77_RS17605 1ce8bdd09e852ca05beedbb68a534877 1078 Gene3D G3DSA:3.40.50.300 644 679 1.5E-42 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS17605 1ce8bdd09e852ca05beedbb68a534877 1078 Gene3D G3DSA:3.40.50.300 731 779 1.5E-42 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS17605 1ce8bdd09e852ca05beedbb68a534877 1078 Gene3D G3DSA:3.40.50.300 346 461 1.5E-42 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS17605 1ce8bdd09e852ca05beedbb68a534877 1078 Gene3D G3DSA:1.10.486.10 462 613 2.0E-16 T 06-07-2017 CAK77_RS09040 a501d81da5776213b01d6ac36e1e148e 306 SUPERFAMILY SSF55048 129 182 3.66E-10 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CAK77_RS09040 a501d81da5776213b01d6ac36e1e148e 306 Gene3D G3DSA:3.40.366.10 2 121 2.5E-49 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAK77_RS09040 a501d81da5776213b01d6ac36e1e148e 306 Gene3D G3DSA:3.40.366.10 189 300 2.5E-49 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAK77_RS09040 a501d81da5776213b01d6ac36e1e148e 306 Pfam PF00698 Acyl transferase domain 7 282 4.7E-23 T 06-07-2017 IPR014043 Acyl transferase CAK77_RS09040 a501d81da5776213b01d6ac36e1e148e 306 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 5 298 2.7E-16 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain CAK77_RS09040 a501d81da5776213b01d6ac36e1e148e 306 SUPERFAMILY SSF52151 183 305 6.8E-59 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAK77_RS09040 a501d81da5776213b01d6ac36e1e148e 306 SUPERFAMILY SSF52151 2 121 6.8E-59 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAK77_RS09040 a501d81da5776213b01d6ac36e1e148e 306 Gene3D G3DSA:3.30.70.250 124 188 2.5E-19 T 06-07-2017 CAK77_RS11585 637c71a5d31804496a3c9ffa1f7eacf4 121 Pfam PF12840 Helix-turn-helix domain 4 63 2.7E-10 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS11585 637c71a5d31804496a3c9ffa1f7eacf4 121 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 55 70 1.3E-10 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK77_RS11585 637c71a5d31804496a3c9ffa1f7eacf4 121 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 40 55 1.3E-10 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK77_RS11585 637c71a5d31804496a3c9ffa1f7eacf4 121 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 4 19 1.3E-10 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK77_RS11585 637c71a5d31804496a3c9ffa1f7eacf4 121 SUPERFAMILY SSF46785 3 101 8.17E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS11585 637c71a5d31804496a3c9ffa1f7eacf4 121 SMART SM00418 2 84 1.9E-18 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK77_RS11585 637c71a5d31804496a3c9ffa1f7eacf4 121 Gene3D G3DSA:1.10.10.10 3 106 3.7E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS07875 96c361565f4e5f9a5407b6b36679492e 1614 PIRSF PIRSF036761 37 1610 0.0 T 06-07-2017 IPR007780 NAD-glutamate dehydrogenase, bacteria GO:0004352|GO:0019551 KEGG: 00220+1.4.1.2|KEGG: 00250+1.4.1.2|KEGG: 00430+1.4.1.2|KEGG: 00910+1.4.1.2|MetaCyc: PWY-5022|MetaCyc: PWY-6728|MetaCyc: PWY-7126 CAK77_RS07875 96c361565f4e5f9a5407b6b36679492e 1614 Gene3D G3DSA:3.40.50.720 944 1055 8.0E-39 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS07875 96c361565f4e5f9a5407b6b36679492e 1614 Gene3D G3DSA:3.40.50.720 1092 1203 8.0E-39 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS07875 96c361565f4e5f9a5407b6b36679492e 1614 SUPERFAMILY SSF53223 761 958 2.21E-22 T 06-07-2017 CAK77_RS07875 96c361565f4e5f9a5407b6b36679492e 1614 Pfam PF05088 Bacterial NAD-glutamate dehydrogenase 93 1603 0.0 T 06-07-2017 IPR028971 NAD-glutamate dehydrogenase GO:0004352|GO:0019551 KEGG: 00220+1.4.1.2|KEGG: 00250+1.4.1.2|KEGG: 00430+1.4.1.2|KEGG: 00910+1.4.1.2|MetaCyc: PWY-5022|MetaCyc: PWY-6728|MetaCyc: PWY-7126 CAK77_RS07875 96c361565f4e5f9a5407b6b36679492e 1614 SUPERFAMILY SSF51735 947 1049 5.18E-28 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS07875 96c361565f4e5f9a5407b6b36679492e 1614 SUPERFAMILY SSF51735 1087 1216 5.18E-28 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS11300 9ec8c881ac1cc255bdd5b1eefe3bbb88 64 Pfam PF01632 Ribosomal protein L35 2 62 1.1E-25 T 06-07-2017 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS11300 9ec8c881ac1cc255bdd5b1eefe3bbb88 64 PRINTS PR00064 Ribosomal protein L35 signature 3 20 2.1E-17 T 06-07-2017 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CAK77_RS11300 9ec8c881ac1cc255bdd5b1eefe3bbb88 64 PRINTS PR00064 Ribosomal protein L35 signature 21 35 2.1E-17 T 06-07-2017 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CAK77_RS11300 9ec8c881ac1cc255bdd5b1eefe3bbb88 64 PRINTS PR00064 Ribosomal protein L35 signature 36 54 2.1E-17 T 06-07-2017 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CAK77_RS11300 9ec8c881ac1cc255bdd5b1eefe3bbb88 64 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 06-07-2017 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS11300 9ec8c881ac1cc255bdd5b1eefe3bbb88 64 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 62 6.9E-27 T 06-07-2017 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CAK77_RS11300 9ec8c881ac1cc255bdd5b1eefe3bbb88 64 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 18.116 T 06-07-2017 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CAK77_RS11300 9ec8c881ac1cc255bdd5b1eefe3bbb88 64 SUPERFAMILY SSF143034 2 62 1.44E-21 T 06-07-2017 CAK77_RS19005 caff253764347b1c6f1c2bd6b4106ef2 448 SUPERFAMILY SSF103473 16 435 1.44E-61 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK77_RS19005 caff253764347b1c6f1c2bd6b4106ef2 448 ProSitePatterns PS00216 Sugar transport proteins signature 1. 305 322 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CAK77_RS19005 caff253764347b1c6f1c2bd6b4106ef2 448 Gene3D G3DSA:1.20.1250.20 27 225 1.7E-23 T 06-07-2017 CAK77_RS19005 caff253764347b1c6f1c2bd6b4106ef2 448 Gene3D G3DSA:1.20.1250.20 249 435 3.5E-19 T 06-07-2017 CAK77_RS19005 caff253764347b1c6f1c2bd6b4106ef2 448 ProSitePatterns PS00217 Sugar transport proteins signature 2. 132 157 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CAK77_RS19005 caff253764347b1c6f1c2bd6b4106ef2 448 Pfam PF00083 Sugar (and other) transporter 29 220 9.6E-24 T 06-07-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CAK77_RS19005 caff253764347b1c6f1c2bd6b4106ef2 448 Pfam PF00083 Sugar (and other) transporter 224 436 2.0E-14 T 06-07-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CAK77_RS22155 53775bea5ff0a8203f18a69b2d8e62f9 443 Pfam PF00108 Thiolase, N-terminal domain 18 286 4.7E-41 T 06-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CAK77_RS22155 53775bea5ff0a8203f18a69b2d8e62f9 443 Pfam PF02803 Thiolase, C-terminal domain 296 442 6.0E-29 T 06-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CAK77_RS22155 53775bea5ff0a8203f18a69b2d8e62f9 443 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 20 442 2.5E-116 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 CAK77_RS22155 53775bea5ff0a8203f18a69b2d8e62f9 443 SUPERFAMILY SSF53901 293 442 3.68E-28 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS22155 53775bea5ff0a8203f18a69b2d8e62f9 443 Gene3D G3DSA:3.40.47.10 179 222 4.6E-41 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS22155 53775bea5ff0a8203f18a69b2d8e62f9 443 Gene3D G3DSA:3.40.47.10 304 442 4.6E-41 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS22155 53775bea5ff0a8203f18a69b2d8e62f9 443 PIRSF PIRSF000429 12 443 1.6E-95 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 CAK77_RS22155 53775bea5ff0a8203f18a69b2d8e62f9 443 SUPERFAMILY SSF53901 18 292 9.22E-53 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS22155 53775bea5ff0a8203f18a69b2d8e62f9 443 Gene3D G3DSA:3.40.47.10 223 298 4.8E-42 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS22155 53775bea5ff0a8203f18a69b2d8e62f9 443 Gene3D G3DSA:3.40.47.10 18 137 4.8E-42 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS18495 0b983be2ae223adc9feefd16d7430355 399 Gene3D G3DSA:3.30.565.10 303 391 2.8E-10 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS18495 0b983be2ae223adc9feefd16d7430355 399 SUPERFAMILY SSF55874 269 389 5.63E-13 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS18495 0b983be2ae223adc9feefd16d7430355 399 Pfam PF04024 PspC domain 7 60 7.2E-12 T 06-07-2017 IPR007168 Phage shock protein, PspC, N-terminal CAK77_RS18495 0b983be2ae223adc9feefd16d7430355 399 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 304 389 1.5E-6 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS21905 f167f01d03cb5cb0c7255522745e74ea 330 SUPERFAMILY SSF53807 43 324 3.02E-35 T 06-07-2017 CAK77_RS21905 f167f01d03cb5cb0c7255522745e74ea 330 Gene3D G3DSA:3.40.50.1980 42 164 3.5E-22 T 06-07-2017 CAK77_RS21905 f167f01d03cb5cb0c7255522745e74ea 330 Gene3D G3DSA:3.40.50.1980 165 325 1.1E-8 T 06-07-2017 CAK77_RS21905 f167f01d03cb5cb0c7255522745e74ea 330 Pfam PF01497 Periplasmic binding protein 59 284 6.4E-21 T 06-07-2017 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CAK77_RS16145 e70ccb12d34f01ebbb1fb4ed2b45d2e7 279 Gene3D G3DSA:3.20.20.30 132 277 6.4E-14 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS16145 e70ccb12d34f01ebbb1fb4ed2b45d2e7 279 Gene3D G3DSA:3.20.20.30 21 122 1.6E-14 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS16145 e70ccb12d34f01ebbb1fb4ed2b45d2e7 279 SUPERFAMILY SSF51679 20 276 8.83E-36 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS16145 e70ccb12d34f01ebbb1fb4ed2b45d2e7 279 Pfam PF00296 Luciferase-like monooxygenase 22 254 2.8E-17 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS16145 e70ccb12d34f01ebbb1fb4ed2b45d2e7 279 TIGRFAM TIGR03620 F420_MSMEG_4141: probable F420-dependent oxidoreductase, MSMEG_4141 family 18 268 8.8E-90 T 06-07-2017 IPR019922 Luciferase-like, F420-dependent oxidoreductase, MSMEG4141, predicted CAK77_RS06215 c4bca1d1ef8cdc69199a1736a41100fa 461 SUPERFAMILY SSF52540 246 408 3.56E-20 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS06215 c4bca1d1ef8cdc69199a1736a41100fa 461 SMART SM00670 31 158 2.8E-17 T 06-07-2017 IPR002716 PIN domain CAK77_RS06215 c4bca1d1ef8cdc69199a1736a41100fa 461 Pfam PF02562 PhoH-like protein 248 452 3.1E-52 T 06-07-2017 IPR003714 PhoH-like protein GO:0005524 CAK77_RS06215 c4bca1d1ef8cdc69199a1736a41100fa 461 SUPERFAMILY SSF88723 123 165 2.06E-9 T 06-07-2017 IPR029060 PIN domain-like CAK77_RS06215 c4bca1d1ef8cdc69199a1736a41100fa 461 SUPERFAMILY SSF88723 32 90 2.06E-9 T 06-07-2017 IPR029060 PIN domain-like CAK77_RS06215 c4bca1d1ef8cdc69199a1736a41100fa 461 Gene3D G3DSA:3.40.50.1010 127 171 5.3E-11 T 06-07-2017 IPR029060 PIN domain-like CAK77_RS06215 c4bca1d1ef8cdc69199a1736a41100fa 461 Gene3D G3DSA:3.40.50.1010 32 90 5.3E-11 T 06-07-2017 IPR029060 PIN domain-like CAK77_RS06215 c4bca1d1ef8cdc69199a1736a41100fa 461 Pfam PF13638 PIN domain 33 171 9.6E-29 T 06-07-2017 IPR002716 PIN domain CAK77_RS06215 c4bca1d1ef8cdc69199a1736a41100fa 461 Gene3D G3DSA:3.40.50.300 246 452 4.0E-51 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS05300 c1f04973eb6dcb21ad8ddc3d0b669e21 807 Pfam PF13361 UvrD-like helicase C-terminal domain 317 681 2.0E-65 T 06-07-2017 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CAK77_RS05300 c1f04973eb6dcb21ad8ddc3d0b669e21 807 Gene3D G3DSA:1.10.10.160 132 215 1.8E-22 T 06-07-2017 IPR013986 DExx box DNA helicase domain CAK77_RS05300 c1f04973eb6dcb21ad8ddc3d0b669e21 807 Gene3D G3DSA:3.40.50.300 618 709 6.1E-69 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS05300 c1f04973eb6dcb21ad8ddc3d0b669e21 807 Gene3D G3DSA:3.40.50.300 326 428 6.1E-69 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS05300 c1f04973eb6dcb21ad8ddc3d0b669e21 807 Gene3D G3DSA:3.40.50.300 22 127 6.4E-69 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS05300 c1f04973eb6dcb21ad8ddc3d0b669e21 807 Gene3D G3DSA:3.40.50.300 216 325 6.4E-69 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS05300 c1f04973eb6dcb21ad8ddc3d0b669e21 807 Gene3D G3DSA:1.10.486.10 429 606 4.2E-44 T 06-07-2017 CAK77_RS05300 c1f04973eb6dcb21ad8ddc3d0b669e21 807 SUPERFAMILY SSF52540 22 708 6.62E-169 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS05300 c1f04973eb6dcb21ad8ddc3d0b669e21 807 TIGRFAM TIGR01073 pcrA: ATP-dependent DNA helicase PcrA 23 805 2.6E-277 T 06-07-2017 IPR005751 ATP-dependent DNA helicase PcrA GO:0004003|GO:0005737|GO:0006268 CAK77_RS05300 c1f04973eb6dcb21ad8ddc3d0b669e21 807 Pfam PF00580 UvrD/REP helicase N-terminal domain 27 311 6.2E-73 T 06-07-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 CAK77_RS03985 f33a26c2de1500a9c9b0e99dd75d6ccf 155 Pfam PF00085 Thioredoxin 65 148 6.5E-12 T 06-07-2017 IPR013766 Thioredoxin domain GO:0045454 CAK77_RS03985 f33a26c2de1500a9c9b0e99dd75d6ccf 155 Gene3D G3DSA:3.40.30.10 62 150 1.5E-18 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK77_RS03985 f33a26c2de1500a9c9b0e99dd75d6ccf 155 ProSitePatterns PS00194 Thioredoxin family active site. 69 87 - T 06-07-2017 IPR017937 Thioredoxin, conserved site GO:0045454 CAK77_RS03985 f33a26c2de1500a9c9b0e99dd75d6ccf 155 SUPERFAMILY SSF52833 64 152 1.67E-20 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK77_RS06750 f7c75c93da0ce2d2490c98b347276c80 317 SUPERFAMILY SSF53448 46 279 8.84E-53 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK77_RS06750 f7c75c93da0ce2d2490c98b347276c80 317 Gene3D G3DSA:3.90.550.10 46 166 8.5E-10 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK77_RS06750 f7c75c93da0ce2d2490c98b347276c80 317 Pfam PF00535 Glycosyl transferase family 2 47 153 2.9E-9 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CAK77_RS12520 9064eff56983fc4c779e4280a1c22a39 290 Pfam PF00582 Universal stress protein family 15 146 1.3E-10 T 06-07-2017 IPR006016 UspA GO:0006950 CAK77_RS12520 9064eff56983fc4c779e4280a1c22a39 290 SUPERFAMILY SSF52402 16 148 5.11E-14 T 06-07-2017 CAK77_RS12520 9064eff56983fc4c779e4280a1c22a39 290 Gene3D G3DSA:3.40.50.620 14 139 1.1E-12 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS12520 9064eff56983fc4c779e4280a1c22a39 290 Gene3D G3DSA:3.40.50.620 140 266 6.8E-10 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS08855 f9e51a379f9d7f8a626b4f0fc0480798 222 Hamap MF_01924 D-alanyl-D-alanine dipeptidase [ddpX]. 43 220 26.201 T 06-07-2017 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 CAK77_RS08855 f9e51a379f9d7f8a626b4f0fc0480798 222 Gene3D G3DSA:3.30.1380.10 42 208 1.8E-51 T 06-07-2017 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 CAK77_RS08855 f9e51a379f9d7f8a626b4f0fc0480798 222 Pfam PF01427 D-ala-D-ala dipeptidase 41 211 3.6E-59 T 06-07-2017 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 CAK77_RS08855 f9e51a379f9d7f8a626b4f0fc0480798 222 SUPERFAMILY SSF55166 42 209 2.71E-48 T 06-07-2017 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 CAK77_RS17995 345e3680a900a8265aa5acc71d2dd4d2 387 SUPERFAMILY SSF56645 10 247 1.7E-78 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK77_RS17995 345e3680a900a8265aa5acc71d2dd4d2 387 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 130 142 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CAK77_RS17995 345e3680a900a8265aa5acc71d2dd4d2 387 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 343 362 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CAK77_RS17995 345e3680a900a8265aa5acc71d2dd4d2 387 Gene3D G3DSA:1.10.540.10 10 124 3.0E-35 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS17995 345e3680a900a8265aa5acc71d2dd4d2 387 Gene3D G3DSA:1.20.140.10 223 386 3.6E-71 T 06-07-2017 CAK77_RS17995 345e3680a900a8265aa5acc71d2dd4d2 387 SUPERFAMILY SSF47203 233 385 5.15E-59 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS17995 345e3680a900a8265aa5acc71d2dd4d2 387 Gene3D G3DSA:2.40.110.10 128 222 4.8E-41 T 06-07-2017 CAK77_RS17995 345e3680a900a8265aa5acc71d2dd4d2 387 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 14 124 3.8E-29 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS17995 345e3680a900a8265aa5acc71d2dd4d2 387 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 128 223 2.6E-30 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAK77_RS17995 345e3680a900a8265aa5acc71d2dd4d2 387 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 235 384 3.0E-51 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS18815 85885364ebfa2b9513961a3bea15f8c9 138 ProSitePatterns PS00054 Ribosomal protein S11 signature. 106 128 - T 06-07-2017 IPR018102 Ribosomal S11, conserved site CAK77_RS18815 85885364ebfa2b9513961a3bea15f8c9 138 Pfam PF00411 Ribosomal protein S11 28 137 7.2E-49 T 06-07-2017 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CAK77_RS18815 85885364ebfa2b9513961a3bea15f8c9 138 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 4 138 34.372 T 06-07-2017 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CAK77_RS18815 85885364ebfa2b9513961a3bea15f8c9 138 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 19 135 5.5E-59 T 06-07-2017 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS18815 85885364ebfa2b9513961a3bea15f8c9 138 Gene3D G3DSA:3.30.420.80 14 138 2.1E-57 T 06-07-2017 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CAK77_RS18815 85885364ebfa2b9513961a3bea15f8c9 138 SUPERFAMILY SSF53137 23 138 5.01E-50 T 06-07-2017 CAK77_RS18815 85885364ebfa2b9513961a3bea15f8c9 138 PIRSF PIRSF002131 8 138 5.1E-55 T 06-07-2017 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CAK77_RS24360 e821c02059a13d6776189fba540cd954 234 Gene3D G3DSA:3.40.50.150 23 215 4.2E-62 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS24360 e821c02059a13d6776189fba540cd954 234 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 26 199 1.4E-40 T 06-07-2017 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CAK77_RS24360 e821c02059a13d6776189fba540cd954 234 PIRSF PIRSF003078 7 215 2.2E-45 T 06-07-2017 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CAK77_RS24360 e821c02059a13d6776189fba540cd954 234 Pfam PF02527 rRNA small subunit methyltransferase G 23 198 2.6E-50 T 06-07-2017 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CAK77_RS24360 e821c02059a13d6776189fba540cd954 234 SUPERFAMILY SSF53335 25 214 2.17E-31 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS24360 e821c02059a13d6776189fba540cd954 234 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 13 210 23.955 T 06-07-2017 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CAK77_RS16915 870666be860978936b1d95c1921019b1 483 SUPERFAMILY SSF51679 2 438 1.09E-122 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS16915 870666be860978936b1d95c1921019b1 483 Gene3D G3DSA:3.20.20.30 353 437 4.6E-130 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS16915 870666be860978936b1d95c1921019b1 483 Gene3D G3DSA:3.20.20.30 2 315 4.6E-130 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS16915 870666be860978936b1d95c1921019b1 483 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 7 435 4.6E-164 T 06-07-2017 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 CAK77_RS16915 870666be860978936b1d95c1921019b1 483 PIRSF PIRSF000337 2 450 1.3E-139 T 06-07-2017 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 CAK77_RS16915 870666be860978936b1d95c1921019b1 483 Pfam PF00296 Luciferase-like monooxygenase 34 390 3.7E-50 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS10570 f56acfda2c2615b9c5162d44546596e0 64 Pfam PF05639 Pup-like protein 3 64 1.1E-22 T 06-07-2017 IPR008515 Ubiquitin-like, Pup CAK77_RS10570 f56acfda2c2615b9c5162d44546596e0 64 TIGRFAM TIGR03687 pupylate_cterm: ubiquitin-like protein Pup 33 64 2.1E-21 T 06-07-2017 IPR008515 Ubiquitin-like, Pup CAK77_RS10570 f56acfda2c2615b9c5162d44546596e0 64 Hamap MF_02106 Prokaryotic ubiquitin-like protein Pup [pup]. 1 64 16.569 T 06-07-2017 IPR008515 Ubiquitin-like, Pup CAK77_RS20995 dd039a7fb25a3f8fab9a414932243d51 266 SUPERFAMILY SSF56219 1 266 1.14E-70 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase CAK77_RS20995 dd039a7fb25a3f8fab9a414932243d51 266 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 266 3.1E-81 T 06-07-2017 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 CAK77_RS20995 dd039a7fb25a3f8fab9a414932243d51 266 Gene3D G3DSA:3.60.10.10 1 266 2.1E-80 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase CAK77_RS20995 dd039a7fb25a3f8fab9a414932243d51 266 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 1 264 7.8E-61 T 06-07-2017 CAK77_RS20995 dd039a7fb25a3f8fab9a414932243d51 266 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 4 258 4.0E-21 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase CAK77_RS11170 6739024ff7a72a1d615572540d654257 481 SUPERFAMILY SSF50249 107 191 1.94E-14 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS11170 6739024ff7a72a1d615572540d654257 481 SUPERFAMILY SSF50249 208 289 4.49E-27 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS11170 6739024ff7a72a1d615572540d654257 481 Gene3D G3DSA:2.40.50.140 111 189 1.4E-15 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS11170 6739024ff7a72a1d615572540d654257 481 Pfam PF00575 S1 RNA binding domain 207 277 2.8E-26 T 06-07-2017 IPR003029 S1 domain GO:0003676 CAK77_RS11170 6739024ff7a72a1d615572540d654257 481 Pfam PF00575 S1 RNA binding domain 291 363 1.8E-22 T 06-07-2017 IPR003029 S1 domain GO:0003676 CAK77_RS11170 6739024ff7a72a1d615572540d654257 481 Pfam PF00575 S1 RNA binding domain 121 188 5.7E-15 T 06-07-2017 IPR003029 S1 domain GO:0003676 CAK77_RS11170 6739024ff7a72a1d615572540d654257 481 Pfam PF00575 S1 RNA binding domain 33 105 5.3E-16 T 06-07-2017 IPR003029 S1 domain GO:0003676 CAK77_RS11170 6739024ff7a72a1d615572540d654257 481 SUPERFAMILY SSF50249 277 365 1.12E-24 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS11170 6739024ff7a72a1d615572540d654257 481 Gene3D G3DSA:2.40.50.140 26 106 4.5E-19 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS11170 6739024ff7a72a1d615572540d654257 481 PRINTS PR00681 Ribosomal protein S1 signature 229 250 1.4E-87 T 06-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 CAK77_RS11170 6739024ff7a72a1d615572540d654257 481 PRINTS PR00681 Ribosomal protein S1 signature 102 121 1.4E-87 T 06-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 CAK77_RS11170 6739024ff7a72a1d615572540d654257 481 PRINTS PR00681 Ribosomal protein S1 signature 346 364 1.4E-87 T 06-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 CAK77_RS11170 6739024ff7a72a1d615572540d654257 481 PRINTS PR00681 Ribosomal protein S1 signature 54 68 1.4E-87 T 06-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 CAK77_RS11170 6739024ff7a72a1d615572540d654257 481 PRINTS PR00681 Ribosomal protein S1 signature 143 160 1.4E-87 T 06-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 CAK77_RS11170 6739024ff7a72a1d615572540d654257 481 PRINTS PR00681 Ribosomal protein S1 signature 172 192 1.4E-87 T 06-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 CAK77_RS11170 6739024ff7a72a1d615572540d654257 481 PRINTS PR00681 Ribosomal protein S1 signature 126 142 1.4E-87 T 06-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 CAK77_RS11170 6739024ff7a72a1d615572540d654257 481 PRINTS PR00681 Ribosomal protein S1 signature 307 326 1.4E-87 T 06-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 CAK77_RS11170 6739024ff7a72a1d615572540d654257 481 PRINTS PR00681 Ribosomal protein S1 signature 36 54 1.4E-87 T 06-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 CAK77_RS11170 6739024ff7a72a1d615572540d654257 481 Gene3D G3DSA:2.40.50.140 284 367 5.2E-28 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS11170 6739024ff7a72a1d615572540d654257 481 Gene3D G3DSA:2.40.50.140 210 283 1.8E-30 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS11170 6739024ff7a72a1d615572540d654257 481 SMART SM00316 34 105 3.5E-17 T 06-07-2017 IPR022967 RNA-binding domain, S1 CAK77_RS11170 6739024ff7a72a1d615572540d654257 481 SMART SM00316 292 363 7.2E-24 T 06-07-2017 IPR022967 RNA-binding domain, S1 CAK77_RS11170 6739024ff7a72a1d615572540d654257 481 SMART SM00316 121 188 7.5E-11 T 06-07-2017 IPR022967 RNA-binding domain, S1 CAK77_RS11170 6739024ff7a72a1d615572540d654257 481 SMART SM00316 207 277 5.1E-28 T 06-07-2017 IPR022967 RNA-binding domain, S1 CAK77_RS11170 6739024ff7a72a1d615572540d654257 481 SUPERFAMILY SSF50249 28 130 1.19E-22 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS13890 5cb8417973ed588f484b8e1b8edf0678 144 PIRSF PIRSF001399 1 144 1.6E-54 T 06-07-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAK77_RS13890 5cb8417973ed588f484b8e1b8edf0678 144 ProSitePatterns PS01029 Dehydroquinase class II signature. 6 23 - T 06-07-2017 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAK77_RS13890 5cb8417973ed588f484b8e1b8edf0678 144 Pfam PF01220 Dehydroquinase class II 3 138 5.9E-52 T 06-07-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAK77_RS13890 5cb8417973ed588f484b8e1b8edf0678 144 SUPERFAMILY SSF52304 1 141 5.76E-53 T 06-07-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAK77_RS13890 5cb8417973ed588f484b8e1b8edf0678 144 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 144 61.383 T 06-07-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAK77_RS13890 5cb8417973ed588f484b8e1b8edf0678 144 TIGRFAM TIGR01088 aroQ: 3-dehydroquinate dehydratase, type II 3 140 2.4E-58 T 06-07-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAK77_RS13890 5cb8417973ed588f484b8e1b8edf0678 144 Gene3D G3DSA:3.40.50.9100 1 141 3.8E-56 T 06-07-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAK77_RS13890 5cb8417973ed588f484b8e1b8edf0678 144 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 3 138 1.0E-56 T 06-07-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAK77_RS23530 6d1fa79a648d0d7815dd830229a0c5ff 622 Gene3D G3DSA:2.120.10.30 19 253 3.0E-22 T 06-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like CAK77_RS23530 6d1fa79a648d0d7815dd830229a0c5ff 622 SUPERFAMILY SSF53474 359 617 3.3E-70 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS23530 6d1fa79a648d0d7815dd830229a0c5ff 622 Pfam PF00326 Prolyl oligopeptidase family 402 617 1.3E-48 T 06-07-2017 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 CAK77_RS23530 6d1fa79a648d0d7815dd830229a0c5ff 622 Gene3D G3DSA:3.40.50.1820 283 616 4.1E-90 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS23530 6d1fa79a648d0d7815dd830229a0c5ff 622 SUPERFAMILY SSF82171 21 344 9.02E-18 T 06-07-2017 CAK77_RS12180 6476016364b015ea8ca19e9172080582 806 ProSitePatterns PS60002 Phosphoketolase signature 1. 155 161 - T 06-07-2017 IPR019790 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, conserved site GO:0005975|GO:0016832 CAK77_RS12180 6476016364b015ea8ca19e9172080582 806 SUPERFAMILY SSF52518 11 380 1.05E-75 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK77_RS12180 6476016364b015ea8ca19e9172080582 806 Hamap MF_01403 Probable phosphoketolase. 16 797 39.817 T 06-07-2017 IPR023962 Probable phosphoketolase CAK77_RS12180 6476016364b015ea8ca19e9172080582 806 PIRSF PIRSF017245 3 797 0.0 T 06-07-2017 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 CAK77_RS12180 6476016364b015ea8ca19e9172080582 806 ProSitePatterns PS60003 Phosphoketolase signature 2. 168 186 - T 06-07-2017 IPR019789 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, thiamine diphosphate binding site GO:0005975|GO:0016832 CAK77_RS12180 6476016364b015ea8ca19e9172080582 806 Pfam PF03894 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase 410 584 1.1E-88 T 06-07-2017 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 CAK77_RS12180 6476016364b015ea8ca19e9172080582 806 Pfam PF09363 XFP C-terminal domain 595 795 5.1E-85 T 06-07-2017 IPR018969 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, C-terminal GO:0005975|GO:0016832 CAK77_RS12180 6476016364b015ea8ca19e9172080582 806 Gene3D G3DSA:3.40.50.970 14 377 6.7E-20 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK77_RS12180 6476016364b015ea8ca19e9172080582 806 Pfam PF09364 XFP N-terminal domain 19 395 3.3E-185 T 06-07-2017 IPR018970 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, N-terminal CAK77_RS12180 6476016364b015ea8ca19e9172080582 806 SUPERFAMILY SSF52518 387 597 1.68E-25 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK77_RS23250 429431a61403f80f1dca2fc1525c720d 238 Gene3D G3DSA:3.40.50.300 12 236 8.4E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS23250 429431a61403f80f1dca2fc1525c720d 238 SUPERFAMILY SSF52540 14 235 9.51E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS23250 429431a61403f80f1dca2fc1525c720d 238 SMART SM00382 43 231 1.8E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS23250 429431a61403f80f1dca2fc1525c720d 238 Pfam PF00005 ABC transporter 34 183 6.1E-25 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK77_RS19345 628e3b01c1fe0af2c2d7ee5eecb63fc9 129 Gene3D G3DSA:1.20.5.710 3 52 7.2E-19 T 06-07-2017 CAK77_RS19345 628e3b01c1fe0af2c2d7ee5eecb63fc9 129 SUPERFAMILY SSF54736 57 129 5.58E-22 T 06-07-2017 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like CAK77_RS19345 628e3b01c1fe0af2c2d7ee5eecb63fc9 129 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 3 129 24.214 T 06-07-2017 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS19345 628e3b01c1fe0af2c2d7ee5eecb63fc9 129 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 62 129 2.6E-28 T 06-07-2017 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS19345 628e3b01c1fe0af2c2d7ee5eecb63fc9 129 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 129 8.6E-50 T 06-07-2017 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS19345 628e3b01c1fe0af2c2d7ee5eecb63fc9 129 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 63 103 2.0E-15 T 06-07-2017 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS19345 628e3b01c1fe0af2c2d7ee5eecb63fc9 129 SUPERFAMILY SSF48300 5 64 6.28E-15 T 06-07-2017 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS19345 628e3b01c1fe0af2c2d7ee5eecb63fc9 129 Gene3D G3DSA:3.30.1390.10 56 129 2.5E-31 T 06-07-2017 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like CAK77_RS19345 628e3b01c1fe0af2c2d7ee5eecb63fc9 129 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 6 53 5.2E-18 T 06-07-2017 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS06655 bf32818119270eafef849a0b711334f5 108 Gene3D G3DSA:3.30.70.20 5 74 4.1E-18 T 06-07-2017 CAK77_RS06655 bf32818119270eafef849a0b711334f5 108 SUPERFAMILY SSF54862 3 85 2.51E-20 T 06-07-2017 CAK77_RS06655 bf32818119270eafef849a0b711334f5 108 PRINTS PR00354 7Fe ferredoxin signature 19 29 2.0E-17 T 06-07-2017 IPR000813 7Fe ferredoxin GO:0009055 CAK77_RS06655 bf32818119270eafef849a0b711334f5 108 PRINTS PR00354 7Fe ferredoxin signature 35 52 2.0E-17 T 06-07-2017 IPR000813 7Fe ferredoxin GO:0009055 CAK77_RS06655 bf32818119270eafef849a0b711334f5 108 PRINTS PR00354 7Fe ferredoxin signature 9 19 2.0E-17 T 06-07-2017 IPR000813 7Fe ferredoxin GO:0009055 CAK77_RS06655 bf32818119270eafef849a0b711334f5 108 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CAK77_RS06655 bf32818119270eafef849a0b711334f5 108 Pfam PF00037 4Fe-4S binding domain 34 55 1.3E-8 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CAK77_RS13525 0d83dfb82293cab2592114cebe2489e7 375 Hamap MF_00493 Transaldolase [tal]. 1 374 163.239 T 06-07-2017 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 CAK77_RS13525 0d83dfb82293cab2592114cebe2489e7 375 PIRSF PIRSF036915 1 375 2.9E-175 T 06-07-2017 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 CAK77_RS13525 0d83dfb82293cab2592114cebe2489e7 375 SUPERFAMILY SSF51569 7 363 1.71E-79 T 06-07-2017 CAK77_RS13525 0d83dfb82293cab2592114cebe2489e7 375 Gene3D G3DSA:3.20.20.70 7 362 1.0E-122 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK77_RS13525 0d83dfb82293cab2592114cebe2489e7 375 Pfam PF00923 Transaldolase 18 362 1.6E-83 T 06-07-2017 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336 CAK77_RS13525 0d83dfb82293cab2592114cebe2489e7 375 TIGRFAM TIGR00876 tal_mycobact: transaldolase 14 362 2.3E-163 T 06-07-2017 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 CAK77_RS13525 0d83dfb82293cab2592114cebe2489e7 375 ProSitePatterns PS00958 Transaldolase active site. 140 157 - T 06-07-2017 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336 CAK77_RS13525 0d83dfb82293cab2592114cebe2489e7 375 ProSitePatterns PS01054 Transaldolase signature 1. 44 52 - T 06-07-2017 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336 CAK77_RS20970 642e4c9e4e543c7f67b83fb7006f5da9 238 Gene3D G3DSA:2.60.40.200 71 235 1.0E-42 T 06-07-2017 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAK77_RS20970 642e4c9e4e543c7f67b83fb7006f5da9 238 ProSitePatterns PS00332 Copper/Zinc superoxide dismutase signature 2. 224 235 - T 06-07-2017 IPR018152 Superoxide dismutase, copper/zinc, binding site GO:0004784|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAK77_RS20970 642e4c9e4e543c7f67b83fb7006f5da9 238 SUPERFAMILY SSF49329 72 236 1.18E-41 T 06-07-2017 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAK77_RS20970 642e4c9e4e543c7f67b83fb7006f5da9 238 Pfam PF00080 Copper/zinc superoxide dismutase (SODC) 79 235 3.9E-26 T 06-07-2017 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAK77_RS11140 f55ccbd2e7a26c7f99536e394b79ad3a 211 Gene3D G3DSA:1.10.357.10 6 201 3.4E-35 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS11140 f55ccbd2e7a26c7f99536e394b79ad3a 211 SUPERFAMILY SSF46689 8 84 1.28E-20 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS11140 f55ccbd2e7a26c7f99536e394b79ad3a 211 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 64 3.2E-19 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS11140 f55ccbd2e7a26c7f99536e394b79ad3a 211 ProSitePatterns PS01081 TetR-type HTH domain signature. 32 62 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CAK77_RS11140 f55ccbd2e7a26c7f99536e394b79ad3a 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 1.2E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS11140 f55ccbd2e7a26c7f99536e394b79ad3a 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 1.2E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS05500 c0a0110e4566633ae7fe787901f0b67c 263 Pfam PF01925 Sulfite exporter TauE/SafE 5 257 2.5E-28 T 06-07-2017 IPR002781 Transmembrane protein TauE-like GO:0016021 CAK77_RS05015 b2346de1a1e07ff404638bc2ad806b4a 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 2.2E-19 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK77_RS05015 b2346de1a1e07ff404638bc2ad806b4a 296 Gene3D G3DSA:3.40.190.10 193 263 1.3E-9 T 06-07-2017 CAK77_RS05015 b2346de1a1e07ff404638bc2ad806b4a 296 Gene3D G3DSA:1.10.10.10 1 85 5.4E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS05015 b2346de1a1e07ff404638bc2ad806b4a 296 Gene3D G3DSA:3.40.190.10 88 192 2.3E-12 T 06-07-2017 CAK77_RS05015 b2346de1a1e07ff404638bc2ad806b4a 296 SUPERFAMILY SSF46785 1 87 2.01E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS05015 b2346de1a1e07ff404638bc2ad806b4a 296 Pfam PF03466 LysR substrate binding domain 87 290 7.1E-31 T 06-07-2017 IPR005119 LysR, substrate-binding CAK77_RS05015 b2346de1a1e07ff404638bc2ad806b4a 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.9E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK77_RS05015 b2346de1a1e07ff404638bc2ad806b4a 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.9E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK77_RS05015 b2346de1a1e07ff404638bc2ad806b4a 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.9E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK77_RS05015 b2346de1a1e07ff404638bc2ad806b4a 296 SUPERFAMILY SSF53850 87 291 7.42E-29 T 06-07-2017 CAK77_RS19540 635be67b95390ac9f7a24ad95cf918db 418 Gene3D G3DSA:3.40.50.1820 333 354 5.2E-6 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS19540 635be67b95390ac9f7a24ad95cf918db 418 Gene3D G3DSA:3.40.50.1820 241 289 5.2E-6 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS19540 635be67b95390ac9f7a24ad95cf918db 418 SUPERFAMILY SSF53474 239 358 6.99E-8 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS07695 6c81e95b13abfef8525254558a1b3f7c 271 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 223 238 - T 06-07-2017 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CAK77_RS07695 6c81e95b13abfef8525254558a1b3f7c 271 PIRSF PIRSF000097 1 266 3.3E-81 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAK77_RS07695 6c81e95b13abfef8525254558a1b3f7c 271 PRINTS PR00069 Aldo-keto reductase signature 190 214 5.1E-43 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAK77_RS07695 6c81e95b13abfef8525254558a1b3f7c 271 PRINTS PR00069 Aldo-keto reductase signature 31 55 5.1E-43 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAK77_RS07695 6c81e95b13abfef8525254558a1b3f7c 271 PRINTS PR00069 Aldo-keto reductase signature 153 182 5.1E-43 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAK77_RS07695 6c81e95b13abfef8525254558a1b3f7c 271 PRINTS PR00069 Aldo-keto reductase signature 87 105 5.1E-43 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAK77_RS07695 6c81e95b13abfef8525254558a1b3f7c 271 PRINTS PR00069 Aldo-keto reductase signature 119 136 5.1E-43 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAK77_RS07695 6c81e95b13abfef8525254558a1b3f7c 271 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 119 136 - T 06-07-2017 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CAK77_RS07695 6c81e95b13abfef8525254558a1b3f7c 271 SUPERFAMILY SSF51430 2 267 3.67E-92 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAK77_RS07695 6c81e95b13abfef8525254558a1b3f7c 271 Pfam PF00248 Aldo/keto reductase family 12 255 1.1E-47 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAK77_RS07695 6c81e95b13abfef8525254558a1b3f7c 271 Gene3D G3DSA:3.20.20.100 2 259 2.0E-98 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAK77_RS00560 ac0970275d8fba804cf2af2473b55582 568 SUPERFAMILY SSF56425 327 502 2.3E-27 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK77_RS00560 ac0970275d8fba804cf2af2473b55582 568 SUPERFAMILY SSF51905 509 567 2.37E-35 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS00560 ac0970275d8fba804cf2af2473b55582 568 SUPERFAMILY SSF51905 213 335 2.37E-35 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS00560 ac0970275d8fba804cf2af2473b55582 568 SUPERFAMILY SSF51905 15 143 2.37E-35 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS00560 ac0970275d8fba804cf2af2473b55582 568 Gene3D G3DSA:3.50.50.60 218 325 5.7E-59 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS00560 ac0970275d8fba804cf2af2473b55582 568 Gene3D G3DSA:3.50.50.60 506 567 5.7E-59 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS00560 ac0970275d8fba804cf2af2473b55582 568 Gene3D G3DSA:3.50.50.60 15 152 5.7E-59 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS00560 ac0970275d8fba804cf2af2473b55582 568 Gene3D G3DSA:3.90.700.10 345 500 1.6E-28 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK77_RS00560 ac0970275d8fba804cf2af2473b55582 568 Pfam PF00890 FAD binding domain 21 550 3.9E-87 T 06-07-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK77_RS06820 f7c054195238cd816c74667bdf42c354 256 SUPERFAMILY SSF88659 166 245 1.59E-16 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS06820 f7c054195238cd816c74667bdf42c354 256 Gene3D G3DSA:1.10.10.10 182 244 2.6E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS06820 f7c054195238cd816c74667bdf42c354 256 Pfam PF04542 Sigma-70 region 2 90 156 8.8E-22 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS06820 f7c054195238cd816c74667bdf42c354 256 SUPERFAMILY SSF88946 86 175 3.3E-25 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS06820 f7c054195238cd816c74667bdf42c354 256 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 87 243 8.3E-31 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS06820 f7c054195238cd816c74667bdf42c354 256 Gene3D G3DSA:1.10.1740.10 78 178 1.2E-27 T 06-07-2017 CAK77_RS06820 f7c054195238cd816c74667bdf42c354 256 Pfam PF08281 Sigma-70, region 4 189 238 9.9E-15 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS18755 8e7525542c0f59ad5020e38d328a221b 544 Pfam PF11203 Putative type VII ESX secretion system translocon, EccE 181 272 4.1E-20 T 06-07-2017 IPR021368 Type VII secretion system protein EccE CAK77_RS18755 8e7525542c0f59ad5020e38d328a221b 544 TIGRFAM TIGR03923 T7SS_EccE: type VII secretion protein EccE 15 353 1.1E-105 T 06-07-2017 IPR021368 Type VII secretion system protein EccE CAK77_RS23990 1509d7cd651c21c707b0c4817f991973 189 Gene3D G3DSA:1.10.357.10 8 165 1.1E-32 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS23990 1509d7cd651c21c707b0c4817f991973 189 SUPERFAMILY SSF48498 85 167 9.85E-8 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS23990 1509d7cd651c21c707b0c4817f991973 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 65 7.0E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS23990 1509d7cd651c21c707b0c4817f991973 189 SUPERFAMILY SSF46689 9 76 3.89E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS23000 0de16b51fa49b7a291b845ad12b49b0e 176 Pfam PF13302 Acetyltransferase (GNAT) domain 10 148 1.4E-25 T 06-07-2017 IPR000182 GNAT domain GO:0008080 CAK77_RS23000 0de16b51fa49b7a291b845ad12b49b0e 176 SUPERFAMILY SSF55729 2 172 1.01E-43 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS23000 0de16b51fa49b7a291b845ad12b49b0e 176 Gene3D G3DSA:3.40.630.30 1 172 1.7E-49 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS02325 f2d4bba9b0d36f190020df07e0022f96 254 SUPERFAMILY SSF55811 62 221 5.15E-28 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAK77_RS02325 f2d4bba9b0d36f190020df07e0022f96 254 ProDom PD012969 UPF0211 RIKEN CDNA ENRICHED MALE FULL-LENGTH LIBRARY ZBTB8OS ADULT C43H8.1 2 96 0.008 T 06-07-2017 IPR023572 Archease domain Reactome: R-HSA-6784531 CAK77_RS02325 f2d4bba9b0d36f190020df07e0022f96 254 ProSitePatterns PS01293 Nudix CoA signature. 85 105 - T 06-07-2017 IPR000059 NUDIX hydrolase, NudL, conserved site GO:0000287|GO:0009132|GO:0016818|GO:0030145 Reactome: R-HSA-390918 CAK77_RS02325 f2d4bba9b0d36f190020df07e0022f96 254 Pfam PF00293 NUDIX domain 73 183 1.9E-12 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 CAK77_RS02325 f2d4bba9b0d36f190020df07e0022f96 254 Gene3D G3DSA:3.90.79.10 58 227 1.6E-32 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAK77_RS07345 76a1ed487c08234a28d080047c8e80ec 232 Hamap MF_00722 Endonuclease NucS [nucS]. 1 224 31.909 T 06-07-2017 IPR002793 Endonuclease NucS CAK77_RS07345 76a1ed487c08234a28d080047c8e80ec 232 Pfam PF01939 Protein of unknown function DUF91 1 232 2.8E-92 T 06-07-2017 IPR002793 Endonuclease NucS CAK77_RS07345 76a1ed487c08234a28d080047c8e80ec 232 SUPERFAMILY SSF52980 126 218 6.97E-5 T 06-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CAK77_RS07345 76a1ed487c08234a28d080047c8e80ec 232 Gene3D G3DSA:3.40.1350.10 126 168 2.0E-4 T 06-07-2017 IPR011856 tRNA endonuclease-like domain GO:0003676|GO:0004518 Reactome: R-HSA-6784531 CAK77_RS22195 2189c4efe08e587823808cdbc83a42c3 296 SUPERFAMILY SSF47240 162 233 4.95E-5 T 06-07-2017 IPR009078 Ferritin-like superfamily CAK77_RS22195 2189c4efe08e587823808cdbc83a42c3 296 PIRSF PIRSF007580 3 288 1.7E-63 T 06-07-2017 IPR016516 Uncharacterised conserved protein UCP07580 CAK77_RS22195 2189c4efe08e587823808cdbc83a42c3 296 Pfam PF10118 Predicted metal-dependent hydrolase 11 272 1.5E-72 T 06-07-2017 IPR016516 Uncharacterised conserved protein UCP07580 CAK77_RS12535 67b210fd72963e4392a8d80759f58fe0 119 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 86 101 9.2E-12 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK77_RS12535 67b210fd72963e4392a8d80759f58fe0 119 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 71 86 9.2E-12 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK77_RS12535 67b210fd72963e4392a8d80759f58fe0 119 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 36 51 9.2E-12 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK77_RS12535 67b210fd72963e4392a8d80759f58fe0 119 Gene3D G3DSA:1.10.10.10 15 118 1.3E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS12535 67b210fd72963e4392a8d80759f58fe0 119 Pfam PF12840 Helix-turn-helix domain 35 94 7.3E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS12535 67b210fd72963e4392a8d80759f58fe0 119 SMART SM00418 34 114 8.3E-25 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK77_RS12535 67b210fd72963e4392a8d80759f58fe0 119 SUPERFAMILY SSF46785 15 118 6.75E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS07170 a4df5e2e283a4cd3bfd8b8772a3da4c2 399 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 11 33 1.7E-11 T 06-07-2017 CAK77_RS07170 a4df5e2e283a4cd3bfd8b8772a3da4c2 399 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 283 298 1.7E-11 T 06-07-2017 CAK77_RS07170 a4df5e2e283a4cd3bfd8b8772a3da4c2 399 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 150 165 1.7E-11 T 06-07-2017 CAK77_RS07170 a4df5e2e283a4cd3bfd8b8772a3da4c2 399 Gene3D G3DSA:3.50.50.60 12 177 2.8E-29 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS07170 a4df5e2e283a4cd3bfd8b8772a3da4c2 399 Gene3D G3DSA:3.50.50.60 271 341 2.8E-29 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS07170 a4df5e2e283a4cd3bfd8b8772a3da4c2 399 Pfam PF01494 FAD binding domain 11 320 1.3E-16 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 CAK77_RS07170 a4df5e2e283a4cd3bfd8b8772a3da4c2 399 SUPERFAMILY SSF51905 12 171 4.19E-47 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS07170 a4df5e2e283a4cd3bfd8b8772a3da4c2 399 SUPERFAMILY SSF51905 270 357 4.19E-47 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS11250 061bd5da99b2eedeefa51148cd14c175 146 PRINTS PR01438 Universal stress protein signature 4 22 5.6E-17 T 06-07-2017 IPR006015 Universal stress protein A CAK77_RS11250 061bd5da99b2eedeefa51148cd14c175 146 PRINTS PR01438 Universal stress protein signature 122 144 5.6E-17 T 06-07-2017 IPR006015 Universal stress protein A CAK77_RS11250 061bd5da99b2eedeefa51148cd14c175 146 PRINTS PR01438 Universal stress protein signature 104 116 5.6E-17 T 06-07-2017 IPR006015 Universal stress protein A CAK77_RS11250 061bd5da99b2eedeefa51148cd14c175 146 SUPERFAMILY SSF52402 2 144 7.2E-28 T 06-07-2017 CAK77_RS11250 061bd5da99b2eedeefa51148cd14c175 146 Pfam PF00582 Universal stress protein family 4 144 1.0E-25 T 06-07-2017 IPR006016 UspA GO:0006950 CAK77_RS11250 061bd5da99b2eedeefa51148cd14c175 146 Gene3D G3DSA:3.40.50.620 2 145 4.6E-31 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS19830 b6c049b8a5a79d269141b1e7bf5f02c4 180 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 3 50 5.6E-6 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 CAK77_RS19830 b6c049b8a5a79d269141b1e7bf5f02c4 180 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 126 172 0.01 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 CAK77_RS19830 b6c049b8a5a79d269141b1e7bf5f02c4 180 Gene3D G3DSA:1.10.1780.10 3 52 2.3E-7 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 CAK77_RS19830 b6c049b8a5a79d269141b1e7bf5f02c4 180 Gene3D G3DSA:1.10.1780.10 64 174 2.2E-17 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 CAK77_RS19830 b6c049b8a5a79d269141b1e7bf5f02c4 180 SUPERFAMILY SSF81923 88 172 7.85E-8 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 CAK77_RS17175 c20705115b11f6fd0a54267be1d98bb9 237 Pfam PF00326 Prolyl oligopeptidase family 78 214 2.8E-13 T 06-07-2017 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 CAK77_RS17175 c20705115b11f6fd0a54267be1d98bb9 237 Gene3D G3DSA:3.40.50.1820 3 232 9.5E-35 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS17175 c20705115b11f6fd0a54267be1d98bb9 237 SUPERFAMILY SSF53474 3 232 1.2E-34 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS02155 6becf84abea0d87f2822d8b355f25067 83 Gene3D G3DSA:1.10.260.40 52 81 1.9E-4 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK77_RS02155 6becf84abea0d87f2822d8b355f25067 83 Pfam PF13936 Helix-turn-helix domain 46 75 1.8E-7 T 06-07-2017 IPR025246 Transposase IS30-like HTH domain CAK77_RS22035 a236219a12ba3952163ce256c8c7772a 486 Gene3D G3DSA:3.40.309.10 273 462 2.3E-63 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAK77_RS22035 a236219a12ba3952163ce256c8c7772a 486 SUPERFAMILY SSF53720 17 482 2.09E-157 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAK77_RS22035 a236219a12ba3952163ce256c8c7772a 486 Pfam PF00171 Aldehyde dehydrogenase family 26 481 6.6E-159 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAK77_RS22035 a236219a12ba3952163ce256c8c7772a 486 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 258 265 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CAK77_RS22035 a236219a12ba3952163ce256c8c7772a 486 Gene3D G3DSA:3.40.605.10 27 272 1.7E-90 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAK77_RS09245 6716814fd256db90ea30aaee7003ece0 320 SUPERFAMILY SSF52540 19 294 2.43E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS09245 6716814fd256db90ea30aaee7003ece0 320 Gene3D G3DSA:3.40.50.300 25 189 4.0E-41 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS09245 6716814fd256db90ea30aaee7003ece0 320 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 43 172 5.3E-63 T 06-07-2017 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 CAK77_RS09245 6716814fd256db90ea30aaee7003ece0 320 PIRSF PIRSF002849 2 318 3.8E-126 T 06-07-2017 IPR016366 ATPase chaperone, AAA-type, MoxR, predicted CAK77_RS09245 6716814fd256db90ea30aaee7003ece0 320 Gene3D G3DSA:1.10.8.300 205 312 1.1E-33 T 06-07-2017 CAK77_RS21475 484c677d0e9bffbc2decaeb1fe19c942 229 PRINTS PR00773 GrpE protein signature 161 176 1.0E-24 T 06-07-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CAK77_RS21475 484c677d0e9bffbc2decaeb1fe19c942 229 PRINTS PR00773 GrpE protein signature 186 205 1.0E-24 T 06-07-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CAK77_RS21475 484c677d0e9bffbc2decaeb1fe19c942 229 PRINTS PR00773 GrpE protein signature 113 128 1.0E-24 T 06-07-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CAK77_RS21475 484c677d0e9bffbc2decaeb1fe19c942 229 PRINTS PR00773 GrpE protein signature 85 101 1.0E-24 T 06-07-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CAK77_RS21475 484c677d0e9bffbc2decaeb1fe19c942 229 Gene3D G3DSA:2.30.22.10 153 208 1.0E-18 T 06-07-2017 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 CAK77_RS21475 484c677d0e9bffbc2decaeb1fe19c942 229 ProSitePatterns PS01071 grpE protein signature. 164 205 - T 06-07-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CAK77_RS21475 484c677d0e9bffbc2decaeb1fe19c942 229 Pfam PF01025 GrpE 58 206 6.3E-31 T 06-07-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CAK77_RS21475 484c677d0e9bffbc2decaeb1fe19c942 229 Hamap MF_01151 Protein GrpE [grpE]. 7 207 16.2 T 06-07-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CAK77_RS21475 484c677d0e9bffbc2decaeb1fe19c942 229 SUPERFAMILY SSF51064 156 208 2.62E-13 T 06-07-2017 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 CAK77_RS21475 484c677d0e9bffbc2decaeb1fe19c942 229 SUPERFAMILY SSF58014 74 150 2.62E-17 T 06-07-2017 CAK77_RS21475 484c677d0e9bffbc2decaeb1fe19c942 229 Gene3D G3DSA:3.90.20.20 72 150 5.4E-20 T 06-07-2017 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 CAK77_RS15960 2e6423459cc596c9b0c14bd0b387c846 297 SUPERFAMILY SSF46785 1 84 3.18E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS15960 2e6423459cc596c9b0c14bd0b387c846 297 Pfam PF03466 LysR substrate binding domain 89 288 7.1E-39 T 06-07-2017 IPR005119 LysR, substrate-binding CAK77_RS15960 2e6423459cc596c9b0c14bd0b387c846 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 2.0E-22 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK77_RS15960 2e6423459cc596c9b0c14bd0b387c846 297 Gene3D G3DSA:3.40.190.10 177 258 2.5E-25 T 06-07-2017 CAK77_RS15960 2e6423459cc596c9b0c14bd0b387c846 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 9.7E-11 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK77_RS15960 2e6423459cc596c9b0c14bd0b387c846 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 9.7E-11 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK77_RS15960 2e6423459cc596c9b0c14bd0b387c846 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 9.7E-11 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK77_RS15960 2e6423459cc596c9b0c14bd0b387c846 297 Gene3D G3DSA:1.10.10.10 1 86 7.8E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS15960 2e6423459cc596c9b0c14bd0b387c846 297 SUPERFAMILY SSF53850 91 291 2.63E-39 T 06-07-2017 CAK77_RS15960 2e6423459cc596c9b0c14bd0b387c846 297 Gene3D G3DSA:3.40.190.10 91 176 1.5E-18 T 06-07-2017 CAK77_RS16810 4a2290f8dff8ffae9a777d5d85af3538 397 SUPERFAMILY SSF53335 46 202 1.42E-9 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS16810 4a2290f8dff8ffae9a777d5d85af3538 397 Gene3D G3DSA:3.40.50.150 88 161 1.7E-6 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS17075 0b89c7d228f9f96d901d7826b8cc16fa 269 SUPERFAMILY SSF51735 22 264 8.8E-66 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS17075 0b89c7d228f9f96d901d7826b8cc16fa 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 192 2.0E-20 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS17075 0b89c7d228f9f96d901d7826b8cc16fa 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 102 113 2.0E-20 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS17075 0b89c7d228f9f96d901d7826b8cc16fa 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 194 211 2.0E-20 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS17075 0b89c7d228f9f96d901d7826b8cc16fa 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 25 42 2.0E-20 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS17075 0b89c7d228f9f96d901d7826b8cc16fa 269 Gene3D G3DSA:3.40.50.720 20 264 3.1E-68 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS17075 0b89c7d228f9f96d901d7826b8cc16fa 269 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 173 192 1.1E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS17075 0b89c7d228f9f96d901d7826b8cc16fa 269 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 102 113 1.1E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS17075 0b89c7d228f9f96d901d7826b8cc16fa 269 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 30 264 1.2E-49 T 06-07-2017 CAK77_RS20675 24b2bf3750113029e56408971498966f 415 Pfam PF13527 Acetyltransferase (GNAT) domain 55 151 3.8E-20 T 06-07-2017 CAK77_RS20675 24b2bf3750113029e56408971498966f 415 SUPERFAMILY SSF55718 314 415 2.24E-18 T 06-07-2017 IPR003033 SCP2 sterol-binding domain CAK77_RS20675 24b2bf3750113029e56408971498966f 415 SUPERFAMILY SSF55729 42 313 1.26E-46 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS20675 24b2bf3750113029e56408971498966f 415 Pfam PF13530 Sterol carrier protein domain 197 410 5.9E-48 T 06-07-2017 IPR025559 Enhanced intracellular survival protein domain CAK77_RS20675 24b2bf3750113029e56408971498966f 415 Gene3D G3DSA:3.40.630.30 58 152 6.6E-16 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS20675 24b2bf3750113029e56408971498966f 415 Gene3D G3DSA:3.40.630.30 155 300 5.6E-20 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS20675 24b2bf3750113029e56408971498966f 415 Gene3D G3DSA:3.30.1050.10 315 403 3.0E-17 T 06-07-2017 IPR003033 SCP2 sterol-binding domain CAK77_RS02260 b6f0116e0d7f3bb62d520d4e7075e220 320 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 53 234 2.0E-9 T 06-07-2017 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 CAK77_RS02260 b6f0116e0d7f3bb62d520d4e7075e220 320 Gene3D G3DSA:3.60.21.10 51 250 4.6E-14 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAK77_RS02260 b6f0116e0d7f3bb62d520d4e7075e220 320 SUPERFAMILY SSF56300 48 299 3.49E-26 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAK77_RS01165 8da1fa84d45c39b246ffa877bd1e1303 226 Gene3D G3DSA:1.20.144.10 33 206 8.5E-26 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CAK77_RS01165 8da1fa84d45c39b246ffa877bd1e1303 226 SUPERFAMILY SSF48317 9 212 1.31E-30 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CAK77_RS01165 8da1fa84d45c39b246ffa877bd1e1303 226 Pfam PF01569 PAP2 superfamily 95 206 3.8E-17 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CAK77_RS01165 8da1fa84d45c39b246ffa877bd1e1303 226 SMART SM00014 94 204 4.6E-20 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CAK77_RS17680 0a072a45e04f8e723bdf84e3161b40a4 227 Gene3D G3DSA:1.20.1260.10 28 140 1.5E-4 T 06-07-2017 IPR012347 Ferritin-related CAK77_RS17680 0a072a45e04f8e723bdf84e3161b40a4 227 Pfam PF13794 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like 20 198 3.4E-59 T 06-07-2017 CAK77_RS17680 0a072a45e04f8e723bdf84e3161b40a4 227 SUPERFAMILY SSF47240 24 226 4.29E-6 T 06-07-2017 IPR009078 Ferritin-like superfamily CAK77_RS05200 dcddb3df6a9096486c572f380456cf11 269 SUPERFAMILY SSF100939 1 264 8.63E-58 T 06-07-2017 IPR016194 SPOC-like, C-terminal domain CAK77_RS05200 dcddb3df6a9096486c572f380456cf11 269 TIGRFAM TIGR02772 Ku_bact: Ku protein 1 261 7.3E-93 T 06-07-2017 IPR009187 Non-homologous end joining protein Ku, prokaryotic type CAK77_RS05200 dcddb3df6a9096486c572f380456cf11 269 PIRSF PIRSF006493 1 269 1.7E-95 T 06-07-2017 IPR009187 Non-homologous end joining protein Ku, prokaryotic type CAK77_RS05200 dcddb3df6a9096486c572f380456cf11 269 SMART SM00559 52 184 9.7E-44 T 06-07-2017 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571 CAK77_RS05200 dcddb3df6a9096486c572f380456cf11 269 Hamap MF_01875 Non-homologous end joining protein Ku [ku]. 1 259 32.854 T 06-07-2017 IPR009187 Non-homologous end joining protein Ku, prokaryotic type CAK77_RS05200 dcddb3df6a9096486c572f380456cf11 269 Gene3D G3DSA:2.40.290.10 4 184 3.0E-14 T 06-07-2017 IPR016194 SPOC-like, C-terminal domain CAK77_RS05200 dcddb3df6a9096486c572f380456cf11 269 Pfam PF02735 Ku70/Ku80 beta-barrel domain 11 191 4.8E-41 T 06-07-2017 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571 CAK77_RS18230 242aaf44b27712e9a03d933cf10c6b1f 289 TIGRFAM TIGR01697 PNPH-PUNA-XAPA: inosine/guanosine/xanthosine phosphorylase family 48 286 3.4E-79 T 06-07-2017 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-74217|Reactome: R-HSA-74259 CAK77_RS18230 242aaf44b27712e9a03d933cf10c6b1f 289 TIGRFAM TIGR01698 PUNP: purine nucleotide phosphorylase 48 286 4.5E-101 T 06-07-2017 IPR011269 Putative purine nucleotide phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 CAK77_RS18230 242aaf44b27712e9a03d933cf10c6b1f 289 SUPERFAMILY SSF53167 34 289 2.5E-74 T 06-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CAK77_RS18230 242aaf44b27712e9a03d933cf10c6b1f 289 PIRSF PIRSF000477 22 289 4.7E-96 T 06-07-2017 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-74217|Reactome: R-HSA-74259 CAK77_RS18230 242aaf44b27712e9a03d933cf10c6b1f 289 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 104 145 - T 06-07-2017 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 CAK77_RS18230 242aaf44b27712e9a03d933cf10c6b1f 289 Gene3D G3DSA:3.40.50.1580 30 289 9.6E-88 T 06-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CAK77_RS18230 242aaf44b27712e9a03d933cf10c6b1f 289 Pfam PF01048 Phosphorylase superfamily 49 286 1.2E-39 T 06-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CAK77_RS01005 ba8c4cbd4b48e7303b83e08e50de55ae 581 SMART SM00701 216 363 3.4E-60 T 06-07-2017 IPR006619 Peptidoglycan recognition protein family domain, metazoa/bacteria GO:0008270|GO:0008745|GO:0009253 CAK77_RS01005 ba8c4cbd4b48e7303b83e08e50de55ae 581 SUPERFAMILY SSF55846 216 405 2.88E-52 T 06-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 CAK77_RS01005 ba8c4cbd4b48e7303b83e08e50de55ae 581 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 238 392 6.3E-10 T 06-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 CAK77_RS01005 ba8c4cbd4b48e7303b83e08e50de55ae 581 SMART SM00644 228 392 7.8E-4 T 06-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 CAK77_RS01005 ba8c4cbd4b48e7303b83e08e50de55ae 581 Gene3D G3DSA:3.40.80.10 213 407 5.7E-53 T 06-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 CAK77_RS01005 ba8c4cbd4b48e7303b83e08e50de55ae 581 Pfam PF08310 LGFP repeat 440 491 6.6E-15 T 06-07-2017 IPR013207 LGFP CAK77_RS13485 451804e29ef0a7f08a7be3bb5888f8f7 286 Pfam PF00005 ABC transporter 1 140 3.8E-25 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK77_RS13485 451804e29ef0a7f08a7be3bb5888f8f7 286 Gene3D G3DSA:3.40.50.300 1 204 9.6E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS13485 451804e29ef0a7f08a7be3bb5888f8f7 286 SMART SM00382 10 188 2.3E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS13485 451804e29ef0a7f08a7be3bb5888f8f7 286 ProSitePatterns PS00211 ABC transporters family signature. 112 126 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK77_RS13485 451804e29ef0a7f08a7be3bb5888f8f7 286 SUPERFAMILY SSF52540 1 201 7.61E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS15160 3f3ffe9ea0f8197e1ad03e819331982a 222 SUPERFAMILY SSF53213 109 216 3.14E-5 T 06-07-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 CAK77_RS19440 ba62d5a46c55d9f7c10d9643c0303104 264 SUPERFAMILY SSF50104 208 264 1.3E-17 T 06-07-2017 IPR008991 Translation protein SH3-like domain CAK77_RS19440 ba62d5a46c55d9f7c10d9643c0303104 264 Pfam PF02357 Transcription termination factor nusG 70 172 9.1E-25 T 06-07-2017 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CAK77_RS19440 ba62d5a46c55d9f7c10d9643c0303104 264 Gene3D G3DSA:3.30.70.940 70 173 7.6E-42 T 06-07-2017 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CAK77_RS19440 ba62d5a46c55d9f7c10d9643c0303104 264 PRINTS PR00338 Transcription termination factor NUSG signature 222 237 4.1E-19 T 06-07-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 CAK77_RS19440 ba62d5a46c55d9f7c10d9643c0303104 264 PRINTS PR00338 Transcription termination factor NUSG signature 123 135 4.1E-19 T 06-07-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 CAK77_RS19440 ba62d5a46c55d9f7c10d9643c0303104 264 PRINTS PR00338 Transcription termination factor NUSG signature 240 256 4.1E-19 T 06-07-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 CAK77_RS19440 ba62d5a46c55d9f7c10d9643c0303104 264 SMART SM00738 68 176 3.8E-48 T 06-07-2017 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CAK77_RS19440 ba62d5a46c55d9f7c10d9643c0303104 264 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 68 264 24.206 T 06-07-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 CAK77_RS19440 ba62d5a46c55d9f7c10d9643c0303104 264 ProSitePatterns PS01014 Transcription termination factor nusG signature. 247 256 - T 06-07-2017 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site CAK77_RS19440 ba62d5a46c55d9f7c10d9643c0303104 264 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 71 264 3.2E-65 T 06-07-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 CAK77_RS19440 ba62d5a46c55d9f7c10d9643c0303104 264 SUPERFAMILY SSF82679 70 173 4.45E-35 T 06-07-2017 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CAK77_RS19440 ba62d5a46c55d9f7c10d9643c0303104 264 Gene3D G3DSA:2.30.30.30 203 264 1.4E-29 T 06-07-2017 IPR014722 Ribosomal protein L2 domain 2 CAK77_RS12935 1726d1c2630046193f1db4fc124c662f 161 SUPERFAMILY SSF54427 6 147 1.04E-32 T 06-07-2017 IPR032710 NTF2-like domain CAK77_RS12935 1726d1c2630046193f1db4fc124c662f 161 Gene3D G3DSA:3.10.450.50 8 142 8.4E-26 T 06-07-2017 IPR032710 NTF2-like domain CAK77_RS12935 1726d1c2630046193f1db4fc124c662f 161 Pfam PF13577 SnoaL-like domain 8 135 2.8E-27 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain CAK77_RS23885 c9b2fa67b078022a1bc18a710cf70216 311 Gene3D G3DSA:1.10.10.60 211 260 5.4E-8 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS23885 c9b2fa67b078022a1bc18a710cf70216 311 SUPERFAMILY SSF46689 260 308 7.17E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS23885 c9b2fa67b078022a1bc18a710cf70216 311 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 260 302 - T 06-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CAK77_RS23885 c9b2fa67b078022a1bc18a710cf70216 311 Pfam PF12833 Helix-turn-helix domain 229 307 8.0E-20 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK77_RS23885 c9b2fa67b078022a1bc18a710cf70216 311 Gene3D G3DSA:1.10.10.60 261 308 1.2E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS23885 c9b2fa67b078022a1bc18a710cf70216 311 SMART SM00342 223 306 3.8E-22 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK77_RS06940 3d8626d946c0dff8cad39b7011284318 423 SUPERFAMILY SSF56601 295 400 4.41E-62 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK77_RS06940 3d8626d946c0dff8cad39b7011284318 423 SUPERFAMILY SSF56601 43 248 4.41E-62 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK77_RS06940 3d8626d946c0dff8cad39b7011284318 423 Gene3D G3DSA:3.40.710.10 36 409 1.6E-66 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK77_RS06940 3d8626d946c0dff8cad39b7011284318 423 Pfam PF00144 Beta-lactamase 54 402 2.1E-59 T 06-07-2017 IPR001466 Beta-lactamase-related CAK77_RS08920 5b642a19d005c3009d9ab4e976cef9e5 325 SUPERFAMILY SSF50129 1 145 1.13E-15 T 06-07-2017 IPR011032 GroES-like CAK77_RS08920 5b642a19d005c3009d9ab4e976cef9e5 325 Gene3D G3DSA:3.40.50.720 140 263 5.4E-21 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS08920 5b642a19d005c3009d9ab4e976cef9e5 325 SUPERFAMILY SSF51735 104 292 9.24E-29 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS08920 5b642a19d005c3009d9ab4e976cef9e5 325 Gene3D G3DSA:3.90.180.10 1 139 3.1E-17 T 06-07-2017 IPR011032 GroES-like CAK77_RS08920 5b642a19d005c3009d9ab4e976cef9e5 325 SMART SM00829 10 322 4.4E-5 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAK77_RS08920 5b642a19d005c3009d9ab4e976cef9e5 325 Pfam PF00107 Zinc-binding dehydrogenase 145 275 8.1E-10 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAK77_RS08720 5758ed5373958fe0923e8401dbd71c04 252 SUPERFAMILY SSF53474 3 137 9.54E-39 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS08720 5758ed5373958fe0923e8401dbd71c04 252 SUPERFAMILY SSF53474 181 251 9.54E-39 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS08720 5758ed5373958fe0923e8401dbd71c04 252 Gene3D G3DSA:3.40.50.1820 2 135 3.3E-38 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS08720 5758ed5373958fe0923e8401dbd71c04 252 Gene3D G3DSA:3.40.50.1820 179 250 3.3E-38 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS08720 5758ed5373958fe0923e8401dbd71c04 252 Pfam PF12146 Serine aminopeptidase, S33 31 138 1.1E-11 T 06-07-2017 IPR022742 Serine aminopeptidase, S33 CAK77_RS02650 0d6294d3c7447fc6063df1ddf3367435 461 SUPERFAMILY SSF52777 36 155 7.45E-9 T 06-07-2017 CAK77_RS02650 0d6294d3c7447fc6063df1ddf3367435 461 TIGRFAM TIGR02946 acyl_WS_DGAT: acyltransferase, WS/DGAT/MGAT 4 459 1.1E-151 T 06-07-2017 IPR014292 Acyltransferase, WS/DGAT/MGAT GO:0016746|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CAK77_RS02650 0d6294d3c7447fc6063df1ddf3367435 461 Pfam PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain 4 265 2.2E-82 T 06-07-2017 IPR004255 O-acyltransferase, WSD1, N-terminal GO:0004144|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CAK77_RS02650 0d6294d3c7447fc6063df1ddf3367435 461 SUPERFAMILY SSF52777 255 453 5.78E-5 T 06-07-2017 CAK77_RS02650 0d6294d3c7447fc6063df1ddf3367435 461 Pfam PF06974 Protein of unknown function (DUF1298) 306 455 1.1E-32 T 06-07-2017 IPR009721 O-acyltransferase WSD1, C-terminal GO:0004144 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CAK77_RS19460 ef68a3b045c439acc398f8ffa5cf6efd 143 Gene3D G3DSA:3.10.129.10 4 133 3.5E-33 T 06-07-2017 IPR029069 HotDog domain CAK77_RS19460 ef68a3b045c439acc398f8ffa5cf6efd 143 Pfam PF01575 MaoC like domain 15 127 9.1E-28 T 06-07-2017 IPR002539 MaoC-like domain CAK77_RS19460 ef68a3b045c439acc398f8ffa5cf6efd 143 SUPERFAMILY SSF54637 6 132 3.48E-23 T 06-07-2017 IPR029069 HotDog domain CAK77_RS15110 62d0efafc483bd2171809a398cf95d1d 227 Gene3D G3DSA:3.10.310.10 1 126 6.2E-28 T 06-07-2017 CAK77_RS15110 62d0efafc483bd2171809a398cf95d1d 227 SUPERFAMILY SSF54506 1 219 2.62E-38 T 06-07-2017 CAK77_RS15110 62d0efafc483bd2171809a398cf95d1d 227 Pfam PF02567 Phenazine biosynthesis-like protein 8 105 1.3E-19 T 06-07-2017 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CAK77_RS15110 62d0efafc483bd2171809a398cf95d1d 227 Pfam PF02567 Phenazine biosynthesis-like protein 138 196 4.0E-5 T 06-07-2017 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CAK77_RS15110 62d0efafc483bd2171809a398cf95d1d 227 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 1 108 2.5E-22 T 06-07-2017 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CAK77_RS15110 62d0efafc483bd2171809a398cf95d1d 227 Gene3D G3DSA:3.10.310.10 148 216 1.9E-9 T 06-07-2017 CAK77_RS10935 bb80b3a2bf615bf4427bc0c9b8e4bb02 248 SMART SM00382 31 211 1.4E-18 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS10935 bb80b3a2bf615bf4427bc0c9b8e4bb02 248 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK77_RS10935 bb80b3a2bf615bf4427bc0c9b8e4bb02 248 Pfam PF00005 ABC transporter 23 161 5.1E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK77_RS10935 bb80b3a2bf615bf4427bc0c9b8e4bb02 248 SUPERFAMILY SSF52540 7 209 1.69E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS10935 bb80b3a2bf615bf4427bc0c9b8e4bb02 248 Gene3D G3DSA:3.40.50.300 6 208 6.3E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS11875 bb6c7ead723abb7911781969f359d3b7 317 Gene3D G3DSA:3.40.50.880 5 208 5.1E-51 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAK77_RS11875 bb6c7ead723abb7911781969f359d3b7 317 Pfam PF01965 DJ-1/PfpI family 4 174 6.7E-19 T 06-07-2017 IPR002818 DJ-1/PfpI CAK77_RS11875 bb6c7ead723abb7911781969f359d3b7 317 Gene3D G3DSA:1.10.10.60 231 266 1.4E-8 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS11875 bb6c7ead723abb7911781969f359d3b7 317 Gene3D G3DSA:1.10.10.60 267 314 1.6E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS11875 bb6c7ead723abb7911781969f359d3b7 317 SMART SM00342 228 312 1.5E-24 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK77_RS11875 bb6c7ead723abb7911781969f359d3b7 317 SUPERFAMILY SSF46689 266 315 1.75E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS11875 bb6c7ead723abb7911781969f359d3b7 317 SUPERFAMILY SSF52317 4 195 7.03E-48 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAK77_RS11875 bb6c7ead723abb7911781969f359d3b7 317 Pfam PF12833 Helix-turn-helix domain 235 313 6.4E-23 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK77_RS22030 38ae70c2026d985bca1b8b8552ac20cc 401 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 216 253 - T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAK77_RS22030 38ae70c2026d985bca1b8b8552ac20cc 401 SUPERFAMILY SSF53383 2 398 1.79E-126 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK77_RS22030 38ae70c2026d985bca1b8b8552ac20cc 401 Gene3D G3DSA:3.40.640.10 35 284 7.1E-84 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK77_RS22030 38ae70c2026d985bca1b8b8552ac20cc 401 Gene3D G3DSA:3.90.1150.10 285 398 4.9E-40 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK77_RS22030 38ae70c2026d985bca1b8b8552ac20cc 401 Pfam PF00202 Aminotransferase class-III 2 397 2.1E-116 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAK77_RS13970 0add9b3682e1b4947ccfa69015c35be3 341 Pfam PF10005 zinc-ribbon domain 4 89 4.3E-22 T 06-07-2017 IPR011201 Zinc-ribbon domain, bacteria CAK77_RS13970 0add9b3682e1b4947ccfa69015c35be3 341 Pfam PF15887 Putative zinc-binding metallo-peptidase 96 331 3.1E-100 T 06-07-2017 IPR031321 Uncharacterised conserved protein UCP012641, putative zinc-binding metallo-peptidase CAK77_RS13970 0add9b3682e1b4947ccfa69015c35be3 341 PIRSF PIRSF012641 1 341 5.9E-139 T 06-07-2017 IPR031321 Uncharacterised conserved protein UCP012641, putative zinc-binding metallo-peptidase CAK77_RS14895 84c2668d53ddf475acfb942c0c49b266 668 Pfam PF13520 Amino acid permease 58 465 1.4E-25 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CAK77_RS20185 211c4b05f2307ae4b551ad8e9551b683 292 Pfam PF02405 Permease MlaE 76 280 1.1E-56 T 06-07-2017 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 CAK77_RS10560 08bcd9a2624edda53c3be0b97a8b53cc 274 Gene3D G3DSA:3.40.50.150 6 235 1.1E-33 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS10560 08bcd9a2624edda53c3be0b97a8b53cc 274 PIRSF PIRSF028177 3 274 1.5E-72 T 06-07-2017 IPR016874 Tetracenomycin polyketide synthesis O-methyltransferase TcmP GO:0017000|GO:1901106 CAK77_RS10560 08bcd9a2624edda53c3be0b97a8b53cc 274 Pfam PF04072 Leucine carboxyl methyltransferase 34 177 7.0E-15 T 06-07-2017 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 CAK77_RS10560 08bcd9a2624edda53c3be0b97a8b53cc 274 SUPERFAMILY SSF53335 15 247 2.96E-54 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS04980 e413589ed5426521635864ac8a65ac4f 467 SMART SM00857 4 153 8.2E-40 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CAK77_RS04980 e413589ed5426521635864ac8a65ac4f 467 Gene3D G3DSA:3.40.50.1390 4 133 8.3E-21 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CAK77_RS04980 e413589ed5426521635864ac8a65ac4f 467 Pfam PF00239 Resolvase, N terminal domain 4 151 2.7E-26 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CAK77_RS04980 e413589ed5426521635864ac8a65ac4f 467 Pfam PF07508 Recombinase 171 258 6.7E-11 T 06-07-2017 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 CAK77_RS04980 e413589ed5426521635864ac8a65ac4f 467 SUPERFAMILY SSF53041 4 152 2.09E-25 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CAK77_RS04980 e413589ed5426521635864ac8a65ac4f 467 Pfam PF13408 Recombinase zinc beta ribbon domain 271 329 1.0E-8 T 06-07-2017 IPR025827 Recombinase zinc beta ribbon domain CAK77_RS01415 1fc8126b3050e7fd5b38db36dc4573c8 291 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 6 246 7.8E-43 T 06-07-2017 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 CAK77_RS01415 1fc8126b3050e7fd5b38db36dc4573c8 291 TIGRFAM TIGR03838 queuosine_YadB: glutamyl-queuosine tRNA(Asp) synthetase 4 269 2.7E-89 T 06-07-2017 IPR022380 Glutamyl-Q tRNA(Asp) synthetase GO:0000166|GO:0006400|GO:0016876 CAK77_RS01415 1fc8126b3050e7fd5b38db36dc4573c8 291 Gene3D G3DSA:3.40.50.620 181 230 3.2E-37 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS01415 1fc8126b3050e7fd5b38db36dc4573c8 291 Gene3D G3DSA:3.40.50.620 5 67 3.2E-37 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS01415 1fc8126b3050e7fd5b38db36dc4573c8 291 Gene3D G3DSA:3.90.800.10 68 178 1.1E-19 T 06-07-2017 CAK77_RS01415 1fc8126b3050e7fd5b38db36dc4573c8 291 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 9 20 - T 06-07-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK77_RS01415 1fc8126b3050e7fd5b38db36dc4573c8 291 SUPERFAMILY SSF52374 5 259 2.6E-71 T 06-07-2017 CAK77_RS01415 1fc8126b3050e7fd5b38db36dc4573c8 291 PRINTS PR00987 Glutamyl-tRNA synthetase signature 20 31 2.4E-14 T 06-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CAK77_RS01415 1fc8126b3050e7fd5b38db36dc4573c8 291 PRINTS PR00987 Glutamyl-tRNA synthetase signature 179 189 2.4E-14 T 06-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CAK77_RS01415 1fc8126b3050e7fd5b38db36dc4573c8 291 PRINTS PR00987 Glutamyl-tRNA synthetase signature 6 18 2.4E-14 T 06-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CAK77_RS01415 1fc8126b3050e7fd5b38db36dc4573c8 291 PRINTS PR00987 Glutamyl-tRNA synthetase signature 35 48 2.4E-14 T 06-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CAK77_RS01415 1fc8126b3050e7fd5b38db36dc4573c8 291 PRINTS PR00987 Glutamyl-tRNA synthetase signature 195 203 2.4E-14 T 06-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CAK77_RS07015 f97ddcbf0201e5cd926a23fa61607274 1143 Gene3D G3DSA:3.40.50.300 961 1115 1.6E-7 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS07015 f97ddcbf0201e5cd926a23fa61607274 1143 Pfam PF13087 AAA domain 942 1111 1.9E-24 T 06-07-2017 CAK77_RS07015 f97ddcbf0201e5cd926a23fa61607274 1143 TIGRFAM TIGR03491 TIGR03491: putative RecB family nuclease, TM0106 family 67 503 2.3E-49 T 06-07-2017 IPR019993 RecB family nuclease, TM0106, putative CAK77_RS07015 f97ddcbf0201e5cd926a23fa61607274 1143 Gene3D G3DSA:3.40.50.300 753 960 2.2E-29 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS07015 f97ddcbf0201e5cd926a23fa61607274 1143 SUPERFAMILY SSF52540 849 1117 5.4E-45 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS07015 f97ddcbf0201e5cd926a23fa61607274 1143 SUPERFAMILY SSF52540 758 816 5.4E-45 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS07015 f97ddcbf0201e5cd926a23fa61607274 1143 SUPERFAMILY SSF53098 354 509 1.18E-6 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAK77_RS07015 f97ddcbf0201e5cd926a23fa61607274 1143 Pfam PF13604 AAA domain 759 916 3.7E-14 T 06-07-2017 CAK77_RS07015 f97ddcbf0201e5cd926a23fa61607274 1143 Pfam PF13482 RNase_H superfamily 313 503 7.2E-20 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAK77_RS02925 99757a9a9a332164be0f42795d217283 182 Pfam PF03061 Thioesterase superfamily 82 152 6.6E-9 T 06-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 CAK77_RS02925 99757a9a9a332164be0f42795d217283 182 Gene3D G3DSA:3.10.129.10 22 166 1.1E-30 T 06-07-2017 IPR029069 HotDog domain CAK77_RS02925 99757a9a9a332164be0f42795d217283 182 SUPERFAMILY SSF54637 39 162 7.62E-27 T 06-07-2017 IPR029069 HotDog domain CAK77_RS03350 b5c95c6fa43be7f213fa1fa3e0c58f46 307 Gene3D G3DSA:3.40.50.720 9 226 3.7E-57 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS03350 b5c95c6fa43be7f213fa1fa3e0c58f46 307 Pfam PF00106 short chain dehydrogenase 20 221 2.5E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS03350 b5c95c6fa43be7f213fa1fa3e0c58f46 307 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 20 37 1.2E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS03350 b5c95c6fa43be7f213fa1fa3e0c58f46 307 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 141 157 1.2E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS03350 b5c95c6fa43be7f213fa1fa3e0c58f46 307 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 96 107 1.2E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS03350 b5c95c6fa43be7f213fa1fa3e0c58f46 307 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 199 1.2E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS03350 b5c95c6fa43be7f213fa1fa3e0c58f46 307 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 147 155 4.4E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS03350 b5c95c6fa43be7f213fa1fa3e0c58f46 307 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 96 107 4.4E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS03350 b5c95c6fa43be7f213fa1fa3e0c58f46 307 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 180 199 4.4E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS03350 b5c95c6fa43be7f213fa1fa3e0c58f46 307 SUPERFAMILY SSF51735 11 275 6.06E-54 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS12905 b67f161cc7682f762e9fdeda05b6944b 390 Pfam PF02653 Branched-chain amino acid transport system / permease component 57 353 2.1E-44 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAK77_RS04505 f2edc6fd20abb0aeeb08d82e933f3b5e 336 SMART SM00342 256 336 7.9E-16 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK77_RS04505 f2edc6fd20abb0aeeb08d82e933f3b5e 336 SUPERFAMILY SSF46689 292 335 1.73E-6 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS04505 f2edc6fd20abb0aeeb08d82e933f3b5e 336 Gene3D G3DSA:1.10.10.60 291 335 1.3E-7 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS04505 f2edc6fd20abb0aeeb08d82e933f3b5e 336 Pfam PF12833 Helix-turn-helix domain 262 335 5.1E-15 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK77_RS04505 f2edc6fd20abb0aeeb08d82e933f3b5e 336 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 30 213 1.0E-31 T 06-07-2017 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal CAK77_RS05630 725581fe7cc5e28a983ba88fd9fb6b69 220 Gene3D G3DSA:1.10.357.10 8 186 4.0E-19 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS05630 725581fe7cc5e28a983ba88fd9fb6b69 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 35 4.9E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS05630 725581fe7cc5e28a983ba88fd9fb6b69 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 66 4.9E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS05630 725581fe7cc5e28a983ba88fd9fb6b69 220 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 66 1.5E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS05630 725581fe7cc5e28a983ba88fd9fb6b69 220 SUPERFAMILY SSF46689 12 85 4.41E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS11220 2a65974725f9ec9db9c3a14f170a0466 332 Gene3D G3DSA:3.30.360.10 147 327 1.6E-51 T 06-07-2017 CAK77_RS11220 2a65974725f9ec9db9c3a14f170a0466 332 Gene3D G3DSA:3.40.50.720 2 146 3.7E-48 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS11220 2a65974725f9ec9db9c3a14f170a0466 332 SUPERFAMILY SSF55347 130 293 4.09E-43 T 06-07-2017 CAK77_RS11220 2a65974725f9ec9db9c3a14f170a0466 332 SUPERFAMILY SSF51735 3 158 2.16E-50 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS11220 2a65974725f9ec9db9c3a14f170a0466 332 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 5 119 6.8E-22 T 06-07-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 CAK77_RS11220 2a65974725f9ec9db9c3a14f170a0466 332 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 136 200 8.4E-5 T 06-07-2017 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 CAK77_RS22075 40c390f14cf5ed1c19d803f5257064ed 88 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 37 52 2.4E-10 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK77_RS22075 40c390f14cf5ed1c19d803f5257064ed 88 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 52 67 2.4E-10 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK77_RS22075 40c390f14cf5ed1c19d803f5257064ed 88 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 4 19 2.4E-10 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK77_RS22075 40c390f14cf5ed1c19d803f5257064ed 88 SUPERFAMILY SSF46785 2 86 5.1E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS22075 40c390f14cf5ed1c19d803f5257064ed 88 SMART SM00418 2 81 4.5E-20 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK77_RS22075 40c390f14cf5ed1c19d803f5257064ed 88 Pfam PF12840 Helix-turn-helix domain 3 58 1.3E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS22075 40c390f14cf5ed1c19d803f5257064ed 88 Gene3D G3DSA:1.10.10.10 2 88 7.9E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS18060 9c6060386a8a749d31bfb9d9c15597cc 549 SUPERFAMILY SSF52096 294 549 9.96E-88 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS18060 9c6060386a8a749d31bfb9d9c15597cc 549 SUPERFAMILY SSF52096 27 277 2.82E-75 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS18060 9c6060386a8a749d31bfb9d9c15597cc 549 Gene3D G3DSA:3.90.226.10 294 549 5.1E-101 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS18060 9c6060386a8a749d31bfb9d9c15597cc 549 Pfam PF01039 Carboxyl transferase domain 51 547 5.0E-198 T 06-07-2017 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAK77_RS18060 9c6060386a8a749d31bfb9d9c15597cc 549 Gene3D G3DSA:3.90.226.10 19 278 8.3E-79 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS06285 5c1fced56442b00142fd17709abe2457 360 Pfam PF14031 Putative serine dehydratase domain 254 342 7.0E-14 T 06-07-2017 IPR026956 D-serine dehydratase-like domain CAK77_RS06285 5c1fced56442b00142fd17709abe2457 360 SMART SM01119 254 343 4.2E-21 T 06-07-2017 IPR026956 D-serine dehydratase-like domain CAK77_RS06285 5c1fced56442b00142fd17709abe2457 360 Gene3D G3DSA:3.20.20.10 25 234 2.1E-25 T 06-07-2017 IPR029066 PLP-binding barrel CAK77_RS06285 5c1fced56442b00142fd17709abe2457 360 SUPERFAMILY SSF51419 21 243 5.63E-37 T 06-07-2017 IPR029066 PLP-binding barrel CAK77_RS06285 5c1fced56442b00142fd17709abe2457 360 Pfam PF01168 Alanine racemase, N-terminal domain 20 237 7.7E-31 T 06-07-2017 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAK77_RS15120 bb3cb0f534e2ed11b8b5bf7483807dea 170 Pfam PF01476 LysM domain 121 168 8.5E-7 T 06-07-2017 IPR018392 LysM domain CAK77_RS15120 bb3cb0f534e2ed11b8b5bf7483807dea 170 SMART SM00257 119 168 9.9E-4 T 06-07-2017 IPR018392 LysM domain CAK77_RS15120 bb3cb0f534e2ed11b8b5bf7483807dea 170 Gene3D G3DSA:3.10.350.10 121 166 7.6E-7 T 06-07-2017 IPR018392 LysM domain CAK77_RS18360 9dc5c56a42368b022099a41d1c443db8 745 PIRSF PIRSF009407 1 744 0.0 T 06-07-2017 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 CAK77_RS18360 9dc5c56a42368b022099a41d1c443db8 745 Pfam PF03971 Monomeric isocitrate dehydrogenase 7 740 0.0 T 06-07-2017 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 CAK77_RS18360 9dc5c56a42368b022099a41d1c443db8 745 SUPERFAMILY SSF53659 5 743 0.0 T 06-07-2017 CAK77_RS18360 9dc5c56a42368b022099a41d1c443db8 745 TIGRFAM TIGR00178 monomer_idh: isocitrate dehydrogenase, NADP-dependent 1 744 0.0 T 06-07-2017 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 CAK77_RS18360 9dc5c56a42368b022099a41d1c443db8 745 Gene3D G3DSA:3.40.718.10 341 364 3.9E-33 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CAK77_RS18360 9dc5c56a42368b022099a41d1c443db8 745 Gene3D G3DSA:3.40.718.10 148 286 3.9E-33 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CAK77_RS18360 9dc5c56a42368b022099a41d1c443db8 745 Gene3D G3DSA:3.40.718.10 541 648 3.9E-33 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CAK77_RS05120 f1fb0569092d0cc0a8f1a1d5565c2024 356 Pfam PF13439 Glycosyltransferase Family 4 71 167 3.0E-14 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 CAK77_RS05120 f1fb0569092d0cc0a8f1a1d5565c2024 356 Gene3D G3DSA:3.40.50.2000 147 333 1.1E-30 T 06-07-2017 CAK77_RS05120 f1fb0569092d0cc0a8f1a1d5565c2024 356 Pfam PF00534 Glycosyl transferases group 1 175 336 2.6E-30 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 CAK77_RS05120 f1fb0569092d0cc0a8f1a1d5565c2024 356 SUPERFAMILY SSF53756 8 354 1.33E-64 T 06-07-2017 CAK77_RS23950 b30eafe02255318021e2b1800731ccda 225 SUPERFAMILY SSF52172 2 176 6.15E-40 T 06-07-2017 IPR011006 CheY-like superfamily CAK77_RS23950 b30eafe02255318021e2b1800731ccda 225 Pfam PF00072 Response regulator receiver domain 3 112 1.1E-24 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK77_RS23950 b30eafe02255318021e2b1800731ccda 225 Gene3D G3DSA:3.40.50.2300 2 121 2.2E-36 T 06-07-2017 CAK77_RS23950 b30eafe02255318021e2b1800731ccda 225 SMART SM00448 1 112 3.4E-37 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK77_RS23950 b30eafe02255318021e2b1800731ccda 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 216 2.6E-23 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAK77_RS23950 b30eafe02255318021e2b1800731ccda 225 Gene3D G3DSA:1.10.10.10 123 217 7.3E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS23950 b30eafe02255318021e2b1800731ccda 225 SMART SM00862 145 216 2.8E-25 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAK77_RS10280 54efd755706f73e47dde1de9ed53606a 254 Gene3D G3DSA:3.40.190.80 139 251 2.5E-27 T 06-07-2017 CAK77_RS10280 54efd755706f73e47dde1de9ed53606a 254 SUPERFAMILY SSF56655 5 250 1.96E-46 T 06-07-2017 CAK77_RS10280 54efd755706f73e47dde1de9ed53606a 254 Gene3D G3DSA:3.30.540.10 7 127 1.1E-20 T 06-07-2017 CAK77_RS10280 54efd755706f73e47dde1de9ed53606a 254 Pfam PF00459 Inositol monophosphatase family 9 229 1.8E-26 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAK77_RS07065 a4c9dbf3cf0049af01035be8f55896b0 339 SUPERFAMILY SSF50182 162 219 4.9E-12 T 06-07-2017 IPR010920 LSM domain CAK77_RS07065 a4c9dbf3cf0049af01035be8f55896b0 339 SUPERFAMILY SSF82861 102 161 1.7E-12 T 06-07-2017 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 CAK77_RS07065 a4c9dbf3cf0049af01035be8f55896b0 339 Pfam PF00924 Mechanosensitive ion channel 121 319 2.5E-36 T 06-07-2017 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 CAK77_RS07065 a4c9dbf3cf0049af01035be8f55896b0 339 Gene3D G3DSA:2.30.30.60 178 220 3.6E-11 T 06-07-2017 CAK77_RS07065 a4c9dbf3cf0049af01035be8f55896b0 339 Gene3D G3DSA:3.30.70.100 235 318 2.7E-7 T 06-07-2017 CAK77_RS07065 a4c9dbf3cf0049af01035be8f55896b0 339 SUPERFAMILY SSF82689 227 319 2.88E-10 T 06-07-2017 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 CAK77_RS07295 9b5686cc6d65f3700d4279c35fef6c43 121 Gene3D G3DSA:2.60.15.10 4 91 2.1E-23 T 06-07-2017 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 CAK77_RS07295 9b5686cc6d65f3700d4279c35fef6c43 121 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 5 84 1.1E-23 T 06-07-2017 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 CAK77_RS07295 9b5686cc6d65f3700d4279c35fef6c43 121 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 2 116 16.035 T 06-07-2017 IPR001469 ATPase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 CAK77_RS07295 9b5686cc6d65f3700d4279c35fef6c43 121 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 4 97 6.7E-23 T 06-07-2017 IPR001469 ATPase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 CAK77_RS07295 9b5686cc6d65f3700d4279c35fef6c43 121 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 17 84 1.0E-24 T 06-07-2017 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 CAK77_RS07295 9b5686cc6d65f3700d4279c35fef6c43 121 SUPERFAMILY SSF51344 4 84 6.28E-19 T 06-07-2017 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 CAK77_RS11685 e036f2392060c7aeb063a4daf30261ec 955 SUPERFAMILY SSF53383 16 446 9.63E-101 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK77_RS11685 e036f2392060c7aeb063a4daf30261ec 955 SUPERFAMILY SSF53383 480 883 4.92E-98 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK77_RS11685 e036f2392060c7aeb063a4daf30261ec 955 SUPERFAMILY SSF53383 926 949 4.92E-98 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK77_RS11685 e036f2392060c7aeb063a4daf30261ec 955 TIGRFAM TIGR00461 gcvP: glycine dehydrogenase 16 947 0.0 T 06-07-2017 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 CAK77_RS11685 e036f2392060c7aeb063a4daf30261ec 955 Hamap MF_00711 Glycine dehydrogenase (decarboxylating) [gcvP]. 7 953 24.863 T 06-07-2017 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 CAK77_RS11685 e036f2392060c7aeb063a4daf30261ec 955 Gene3D G3DSA:3.40.640.10 501 738 3.0E-39 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK77_RS11685 e036f2392060c7aeb063a4daf30261ec 955 Gene3D G3DSA:3.40.640.10 92 309 5.9E-15 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK77_RS11685 e036f2392060c7aeb063a4daf30261ec 955 Pfam PF02347 Glycine cleavage system P-protein 15 446 1.4E-179 T 06-07-2017 IPR020580 Glycine cleavage system P-protein, N-terminal GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 CAK77_RS11685 e036f2392060c7aeb063a4daf30261ec 955 Pfam PF02347 Glycine cleavage system P-protein 476 733 4.8E-11 T 06-07-2017 IPR020580 Glycine cleavage system P-protein, N-terminal GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 CAK77_RS03845 6589dd588e18f90b9a40e295c6681044 484 Pfam PF01580 FtsK/SpoIIIE family 208 398 7.1E-18 T 06-07-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CAK77_RS03845 6589dd588e18f90b9a40e295c6681044 484 SMART SM00382 226 394 1.1E-4 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS03845 6589dd588e18f90b9a40e295c6681044 484 Gene3D G3DSA:3.40.50.300 209 447 1.6E-19 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS03845 6589dd588e18f90b9a40e295c6681044 484 SUPERFAMILY SSF52540 193 447 1.07E-21 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS07790 33d92154f2d16ba7350f57ca1ad0c362 267 Pfam PF09037 Stf0 sulphotransferase 7 259 4.1E-104 T 06-07-2017 IPR024628 Sulphotransferase Stf0, domain CAK77_RS07790 33d92154f2d16ba7350f57ca1ad0c362 267 Gene3D G3DSA:3.40.50.300 5 266 3.6E-104 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS07790 33d92154f2d16ba7350f57ca1ad0c362 267 PIRSF PIRSF021497 1 267 3.7E-110 T 06-07-2017 IPR015124 Trehalose 2-sulfotransferase GO:0016740 CAK77_RS07790 33d92154f2d16ba7350f57ca1ad0c362 267 SUPERFAMILY SSF52540 3 266 4.56E-91 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS09910 43bac912f76049c3e1a1a0a6e7b3c630 366 SUPERFAMILY SSF51735 154 320 3.02E-22 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS09910 43bac912f76049c3e1a1a0a6e7b3c630 366 SUPERFAMILY SSF50129 4 186 1.63E-35 T 06-07-2017 IPR011032 GroES-like CAK77_RS09910 43bac912f76049c3e1a1a0a6e7b3c630 366 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 140 1.0E-22 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAK77_RS09910 43bac912f76049c3e1a1a0a6e7b3c630 366 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 06-07-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CAK77_RS09910 43bac912f76049c3e1a1a0a6e7b3c630 366 Gene3D G3DSA:3.90.180.10 4 183 5.5E-35 T 06-07-2017 IPR011032 GroES-like CAK77_RS09910 43bac912f76049c3e1a1a0a6e7b3c630 366 Gene3D G3DSA:3.40.50.720 184 304 1.4E-22 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS09910 43bac912f76049c3e1a1a0a6e7b3c630 366 Pfam PF00107 Zinc-binding dehydrogenase 189 311 3.5E-20 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAK77_RS21925 192dbf47b542e31aca48ae4448947dad 291 SMART SM00797 26 290 8.6E-100 T 06-07-2017 IPR003778 Carboxyltransferase domain, subdomain A and B CAK77_RS21925 192dbf47b542e31aca48ae4448947dad 291 SUPERFAMILY SSF50891 176 284 2.47E-14 T 06-07-2017 IPR029000 Cyclophilin-like domain CAK77_RS21925 192dbf47b542e31aca48ae4448947dad 291 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 4 289 1.2E-101 T 06-07-2017 IPR003778 Carboxyltransferase domain, subdomain A and B CAK77_RS21925 192dbf47b542e31aca48ae4448947dad 291 Pfam PF02626 Allophanate hydrolase subunit 2 27 284 7.8E-82 T 06-07-2017 IPR003778 Carboxyltransferase domain, subdomain A and B CAK77_RS21925 192dbf47b542e31aca48ae4448947dad 291 Gene3D G3DSA:2.40.100.10 176 284 8.5E-10 T 06-07-2017 IPR029000 Cyclophilin-like domain CAK77_RS22515 d3cf2da981514cfbb2acf8b73069ff89 507 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 328 498 1.6E-20 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CAK77_RS22515 d3cf2da981514cfbb2acf8b73069ff89 507 Gene3D G3DSA:3.30.70.1230 327 499 1.2E-27 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CAK77_RS22515 d3cf2da981514cfbb2acf8b73069ff89 507 SMART SM00044 295 486 3.6E-5 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CAK77_RS22515 d3cf2da981514cfbb2acf8b73069ff89 507 SUPERFAMILY SSF158472 250 292 3.79E-7 T 06-07-2017 CAK77_RS22515 d3cf2da981514cfbb2acf8b73069ff89 507 SMART SM00304 247 299 7.0E-10 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAK77_RS22515 d3cf2da981514cfbb2acf8b73069ff89 507 SUPERFAMILY SSF55073 323 501 4.87E-41 T 06-07-2017 IPR029787 Nucleotide cyclase CAK77_RS22515 d3cf2da981514cfbb2acf8b73069ff89 507 Pfam PF00672 HAMP domain 228 292 2.4E-11 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAK77_RS11490 966f7b5126d3213daab7b23ac13c9905 306 Hamap MF_00361 NAD kinase [nadK]. 4 298 29.281 T 06-07-2017 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 CAK77_RS11490 966f7b5126d3213daab7b23ac13c9905 306 Gene3D G3DSA:3.40.50.10330 4 154 2.3E-35 T 06-07-2017 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 CAK77_RS11490 966f7b5126d3213daab7b23ac13c9905 306 Gene3D G3DSA:2.60.200.30 155 272 2.9E-36 T 06-07-2017 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 CAK77_RS11490 966f7b5126d3213daab7b23ac13c9905 306 Pfam PF01513 ATP-NAD kinase 5 282 1.6E-72 T 06-07-2017 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 CAK77_RS11490 966f7b5126d3213daab7b23ac13c9905 306 SUPERFAMILY SSF111331 5 304 1.22E-78 T 06-07-2017 IPR016064 NAD kinase/diacylglycerol kinase-like domain CAK77_RS16895 a0239f657da975895f5fb53cda4bdd04 196 SUPERFAMILY SSF46689 7 90 4.93E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS16895 a0239f657da975895f5fb53cda4bdd04 196 Gene3D G3DSA:1.10.357.10 9 193 8.3E-28 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS16895 a0239f657da975895f5fb53cda4bdd04 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 57 4.6E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS16895 a0239f657da975895f5fb53cda4bdd04 196 Pfam PF13977 Bacterial transcriptional repressor 91 194 2.4E-8 T 06-07-2017 CAK77_RS16895 a0239f657da975895f5fb53cda4bdd04 196 SUPERFAMILY SSF48498 90 194 3.5E-8 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS00920 c18f0ce9627838cbf83a92375afc029f 557 Pfam PF13845 Septum formation 170 397 3.7E-81 T 06-07-2017 IPR026004 Septum formation-related domain CAK77_RS21875 d6d8de9a139582508a78edc937e49b4b 259 Pfam PF09339 IclR helix-turn-helix domain 15 65 5.1E-14 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAK77_RS21875 d6d8de9a139582508a78edc937e49b4b 259 SMART SM00346 12 103 1.8E-16 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAK77_RS21875 d6d8de9a139582508a78edc937e49b4b 259 Pfam PF01614 Bacterial transcriptional regulator 137 255 2.8E-13 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAK77_RS21875 d6d8de9a139582508a78edc937e49b4b 259 Gene3D G3DSA:3.30.450.40 82 251 3.9E-32 T 06-07-2017 IPR029016 GAF domain-like CAK77_RS21875 d6d8de9a139582508a78edc937e49b4b 259 Gene3D G3DSA:1.10.10.10 14 81 2.2E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS21875 d6d8de9a139582508a78edc937e49b4b 259 SUPERFAMILY SSF55781 78 256 8.5E-35 T 06-07-2017 IPR029016 GAF domain-like CAK77_RS21875 d6d8de9a139582508a78edc937e49b4b 259 SUPERFAMILY SSF46785 14 84 1.2E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS23695 03249e8cadf41f34eca629905ddb00ac 418 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 283 298 2.9E-15 T 06-07-2017 CAK77_RS23695 03249e8cadf41f34eca629905ddb00ac 418 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 157 172 2.9E-15 T 06-07-2017 CAK77_RS23695 03249e8cadf41f34eca629905ddb00ac 418 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 298 314 2.9E-15 T 06-07-2017 CAK77_RS23695 03249e8cadf41f34eca629905ddb00ac 418 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 2.9E-15 T 06-07-2017 CAK77_RS23695 03249e8cadf41f34eca629905ddb00ac 418 Pfam PF01494 FAD binding domain 5 326 1.9E-55 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 CAK77_RS23695 03249e8cadf41f34eca629905ddb00ac 418 Gene3D G3DSA:3.50.50.60 281 320 6.8E-45 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS23695 03249e8cadf41f34eca629905ddb00ac 418 Gene3D G3DSA:3.50.50.60 3 181 6.8E-45 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS23695 03249e8cadf41f34eca629905ddb00ac 418 SUPERFAMILY SSF51905 270 370 3.44E-55 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS23695 03249e8cadf41f34eca629905ddb00ac 418 SUPERFAMILY SSF51905 5 178 3.44E-55 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS09755 4f943d6148d1e21f10af654e5187ae1f 382 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 200 361 4.1E-38 T 06-07-2017 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 CAK77_RS09755 4f943d6148d1e21f10af654e5187ae1f 382 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 9 365 3.7E-83 T 06-07-2017 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CAK77_RS09755 4f943d6148d1e21f10af654e5187ae1f 382 Gene3D G3DSA:3.40.50.2000 200 366 2.2E-17 T 06-07-2017 CAK77_RS09755 4f943d6148d1e21f10af654e5187ae1f 382 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 10 154 2.5E-38 T 06-07-2017 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CAK77_RS09755 4f943d6148d1e21f10af654e5187ae1f 382 Gene3D G3DSA:3.40.50.2000 8 199 7.5E-60 T 06-07-2017 CAK77_RS09755 4f943d6148d1e21f10af654e5187ae1f 382 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 10 370 31.052 T 06-07-2017 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CAK77_RS09755 4f943d6148d1e21f10af654e5187ae1f 382 SUPERFAMILY SSF53756 10 371 3.14E-96 T 06-07-2017 CAK77_RS08850 ee13f84d156c394b3acdfd2570712213 344 Gene3D G3DSA:2.40.180.10 42 336 4.5E-60 T 06-07-2017 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAK77_RS08850 ee13f84d156c394b3acdfd2570712213 344 PIRSF PIRSF000296 9 333 1.9E-87 T 06-07-2017 IPR024168 Catalase, SrpA-type, predicted CAK77_RS08850 ee13f84d156c394b3acdfd2570712213 344 Pfam PF00199 Catalase 59 329 2.7E-8 T 06-07-2017 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAK77_RS08850 ee13f84d156c394b3acdfd2570712213 344 SUPERFAMILY SSF56634 38 330 1.7E-60 T 06-07-2017 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAK77_RS16515 17ad6039f20fc8e95b7b49b8ff5a8347 167 Gene3D G3DSA:3.30.70.260 4 79 3.7E-34 T 06-07-2017 CAK77_RS16515 17ad6039f20fc8e95b7b49b8ff5a8347 167 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 4 77 9.0E-31 T 06-07-2017 CAK77_RS16515 17ad6039f20fc8e95b7b49b8ff5a8347 167 Pfam PF01842 ACT domain 5 70 7.5E-20 T 06-07-2017 IPR002912 ACT domain GO:0008152|GO:0016597 CAK77_RS16515 17ad6039f20fc8e95b7b49b8ff5a8347 167 SUPERFAMILY SSF55021 5 76 5.0E-23 T 06-07-2017 CAK77_RS16515 17ad6039f20fc8e95b7b49b8ff5a8347 167 Pfam PF10369 Small subunit of acetolactate synthase 86 159 4.2E-30 T 06-07-2017 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 CAK77_RS16515 17ad6039f20fc8e95b7b49b8ff5a8347 167 SUPERFAMILY SSF55021 81 162 2.9E-27 T 06-07-2017 CAK77_RS16515 17ad6039f20fc8e95b7b49b8ff5a8347 167 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 4 160 1.1E-61 T 06-07-2017 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 CAK77_RS16515 17ad6039f20fc8e95b7b49b8ff5a8347 167 Gene3D G3DSA:3.30.70.1150 86 163 1.9E-32 T 06-07-2017 CAK77_RS12355 39b7179c85fb68c8bbecd3ec0dd67b78 205 Pfam PF13649 Methyltransferase domain 52 147 1.0E-14 T 06-07-2017 CAK77_RS12355 39b7179c85fb68c8bbecd3ec0dd67b78 205 SUPERFAMILY SSF53335 14 184 7.69E-29 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS12355 39b7179c85fb68c8bbecd3ec0dd67b78 205 Gene3D G3DSA:3.40.50.150 19 200 3.2E-32 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS18475 8bf6630549b91e7cf282426e522f4ef2 343 Gene3D G3DSA:3.90.245.10 3 333 6.0E-97 T 06-07-2017 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain CAK77_RS18475 8bf6630549b91e7cf282426e522f4ef2 343 SUPERFAMILY SSF53590 1 332 1.44E-84 T 06-07-2017 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain CAK77_RS18475 8bf6630549b91e7cf282426e522f4ef2 343 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 3 326 4.6E-67 T 06-07-2017 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain CAK77_RS10495 823f1b49398ef979d05a73560a3c8067 673 SMART SM00939 393 661 2.9E-32 T 06-07-2017 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 CAK77_RS10495 823f1b49398ef979d05a73560a3c8067 673 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 72 373 2.3E-41 T 06-07-2017 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 CAK77_RS10495 823f1b49398ef979d05a73560a3c8067 673 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 72 635 1.3E-69 T 06-07-2017 IPR005674 CocE/Serine esterase GO:0016787 CAK77_RS10495 823f1b49398ef979d05a73560a3c8067 673 SUPERFAMILY SSF53474 48 421 4.06E-47 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS10495 823f1b49398ef979d05a73560a3c8067 673 SUPERFAMILY SSF49785 394 446 7.01E-29 T 06-07-2017 IPR008979 Galactose-binding domain-like CAK77_RS10495 823f1b49398ef979d05a73560a3c8067 673 SUPERFAMILY SSF49785 480 665 7.01E-29 T 06-07-2017 IPR008979 Galactose-binding domain-like CAK77_RS10495 823f1b49398ef979d05a73560a3c8067 673 Gene3D G3DSA:3.40.50.1820 43 250 9.6E-66 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS10495 823f1b49398ef979d05a73560a3c8067 673 Gene3D G3DSA:3.40.50.1820 317 422 9.6E-66 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS10495 823f1b49398ef979d05a73560a3c8067 673 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 405 660 1.1E-28 T 06-07-2017 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 CAK77_RS10495 823f1b49398ef979d05a73560a3c8067 673 Gene3D G3DSA:2.60.120.260 423 665 8.5E-37 T 06-07-2017 IPR008979 Galactose-binding domain-like CAK77_RS00785 89290465f844235a36a54da86a0571d6 356 SUPERFAMILY SSF55073 204 353 1.02E-28 T 06-07-2017 IPR029787 Nucleotide cyclase CAK77_RS00785 89290465f844235a36a54da86a0571d6 356 SMART SM00267 188 355 1.9E-27 T 06-07-2017 IPR000160 GGDEF domain CAK77_RS00785 89290465f844235a36a54da86a0571d6 356 Pfam PF00990 Diguanylate cyclase, GGDEF domain 199 350 2.2E-28 T 06-07-2017 IPR000160 GGDEF domain CAK77_RS00785 89290465f844235a36a54da86a0571d6 356 Gene3D G3DSA:3.30.70.270 201 353 2.6E-31 T 06-07-2017 CAK77_RS00785 89290465f844235a36a54da86a0571d6 356 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 198 352 3.8E-30 T 06-07-2017 IPR000160 GGDEF domain CAK77_RS20520 a405311ae79d7dafc48ca85d915a22db 266 SUPERFAMILY SSF54637 21 155 1.46E-16 T 06-07-2017 IPR029069 HotDog domain CAK77_RS20520 a405311ae79d7dafc48ca85d915a22db 266 SUPERFAMILY SSF54637 160 237 8.89E-12 T 06-07-2017 IPR029069 HotDog domain CAK77_RS20520 a405311ae79d7dafc48ca85d915a22db 266 Pfam PF01643 Acyl-ACP thioesterase 22 235 1.1E-49 T 06-07-2017 IPR002864 Acyl-ACP thioesterase GO:0006633|GO:0016790 CAK77_RS20520 a405311ae79d7dafc48ca85d915a22db 266 Gene3D G3DSA:3.10.129.10 26 144 1.1E-8 T 06-07-2017 IPR029069 HotDog domain CAK77_RS20520 a405311ae79d7dafc48ca85d915a22db 266 Gene3D G3DSA:3.10.129.10 170 236 8.2E-7 T 06-07-2017 IPR029069 HotDog domain CAK77_RS05285 3ddf9ee42af703d8f126f2c5dbfb0d0f 545 SUPERFAMILY SSF53697 5 542 1.2E-203 T 06-07-2017 CAK77_RS05285 3ddf9ee42af703d8f126f2c5dbfb0d0f 545 Gene3D G3DSA:3.40.50.10490 93 284 7.2E-85 T 06-07-2017 CAK77_RS05285 3ddf9ee42af703d8f126f2c5dbfb0d0f 545 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 40 516 41.447 T 06-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK77_RS05285 3ddf9ee42af703d8f126f2c5dbfb0d0f 545 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 489 506 - T 06-07-2017 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK77_RS05285 3ddf9ee42af703d8f126f2c5dbfb0d0f 545 Gene3D G3DSA:1.10.1390.10 499 541 1.4E-15 T 06-07-2017 IPR023096 Phosphoglucose isomerase, C-terminal GO:0004347|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK77_RS05285 3ddf9ee42af703d8f126f2c5dbfb0d0f 545 Gene3D G3DSA:3.40.50.10490 5 92 3.7E-131 T 06-07-2017 CAK77_RS05285 3ddf9ee42af703d8f126f2c5dbfb0d0f 545 Gene3D G3DSA:3.40.50.10490 287 498 3.7E-131 T 06-07-2017 CAK77_RS05285 3ddf9ee42af703d8f126f2c5dbfb0d0f 545 Pfam PF00342 Phosphoglucose isomerase 46 534 1.1E-205 T 06-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK77_RS05285 3ddf9ee42af703d8f126f2c5dbfb0d0f 545 ProSitePatterns PS00765 Phosphoglucose isomerase signature 1. 259 272 - T 06-07-2017 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK77_RS05285 3ddf9ee42af703d8f126f2c5dbfb0d0f 545 PRINTS PR00662 Glucose-6-phosphate isomerase signature 255 273 3.7E-55 T 06-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK77_RS05285 3ddf9ee42af703d8f126f2c5dbfb0d0f 545 PRINTS PR00662 Glucose-6-phosphate isomerase signature 475 489 3.7E-55 T 06-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK77_RS05285 3ddf9ee42af703d8f126f2c5dbfb0d0f 545 PRINTS PR00662 Glucose-6-phosphate isomerase signature 332 353 3.7E-55 T 06-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK77_RS05285 3ddf9ee42af703d8f126f2c5dbfb0d0f 545 PRINTS PR00662 Glucose-6-phosphate isomerase signature 457 475 3.7E-55 T 06-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK77_RS05285 3ddf9ee42af703d8f126f2c5dbfb0d0f 545 PRINTS PR00662 Glucose-6-phosphate isomerase signature 144 163 3.7E-55 T 06-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK77_RS05285 3ddf9ee42af703d8f126f2c5dbfb0d0f 545 PRINTS PR00662 Glucose-6-phosphate isomerase signature 489 502 3.7E-55 T 06-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK77_RS01125 4f09dab962306c0c087d267d80bcef60 507 Pfam PF01565 FAD binding domain 70 207 1.5E-25 T 06-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CAK77_RS01125 4f09dab962306c0c087d267d80bcef60 507 SUPERFAMILY SSF56176 67 236 3.6E-36 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAK77_RS01125 4f09dab962306c0c087d267d80bcef60 507 Gene3D G3DSA:3.30.465.10 124 237 1.4E-26 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAK77_RS01125 4f09dab962306c0c087d267d80bcef60 507 Pfam PF04030 D-arabinono-1,4-lactone oxidase 440 503 1.1E-7 T 06-07-2017 IPR007173 D-arabinono-1,4-lactone oxidase GO:0003885|GO:0016020|GO:0055114 CAK77_RS20855 679a61fd700299330f0f1c9978313c05 286 Pfam PF04480 Protein of unknown function (DUF559) 216 278 3.3E-6 T 06-07-2017 IPR007569 Domain of unknown function DUF559 CAK77_RS20855 679a61fd700299330f0f1c9978313c05 286 SUPERFAMILY SSF52980 177 280 1.29E-7 T 06-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CAK77_RS15800 42b35363b94837912b02c41ea959a0c6 373 Gene3D G3DSA:3.20.20.70 121 347 1.1E-17 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK77_RS15800 42b35363b94837912b02c41ea959a0c6 373 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 21 373 65.916 T 06-07-2017 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CAK77_RS15800 42b35363b94837912b02c41ea959a0c6 373 SUPERFAMILY SSF102114 115 343 4.05E-17 T 06-07-2017 CAK77_RS15800 42b35363b94837912b02c41ea959a0c6 373 Pfam PF04055 Radical SAM superfamily 126 299 9.2E-21 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 CAK77_RS15800 42b35363b94837912b02c41ea959a0c6 373 PIRSF PIRSF006004 16 373 7.8E-118 T 06-07-2017 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CAK77_RS15800 42b35363b94837912b02c41ea959a0c6 373 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 23 372 2.5E-95 T 06-07-2017 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CAK77_RS07525 17eb10a2383bbc6e9ef41ab722041ff1 743 Gene3D G3DSA:3.40.50.740 314 471 2.0E-42 T 06-07-2017 CAK77_RS07525 17eb10a2383bbc6e9ef41ab722041ff1 743 Gene3D G3DSA:3.40.50.740 62 133 2.0E-42 T 06-07-2017 CAK77_RS07525 17eb10a2383bbc6e9ef41ab722041ff1 743 SUPERFAMILY SSF50692 606 738 4.29E-25 T 06-07-2017 IPR009010 Aspartate decarboxylase-like domain CAK77_RS07525 17eb10a2383bbc6e9ef41ab722041ff1 743 SMART SM00926 3 57 2.3E-10 T 06-07-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS07525 17eb10a2383bbc6e9ef41ab722041ff1 743 Pfam PF00384 Molybdopterin oxidoreductase 60 440 1.4E-33 T 06-07-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS07525 17eb10a2383bbc6e9ef41ab722041ff1 743 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 4 54 1.9E-9 T 06-07-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS07525 17eb10a2383bbc6e9ef41ab722041ff1 743 Pfam PF01568 Molydopterin dinucleotide binding domain 617 732 1.7E-18 T 06-07-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CAK77_RS07525 17eb10a2383bbc6e9ef41ab722041ff1 743 Gene3D G3DSA:3.40.228.10 151 313 1.6E-40 T 06-07-2017 CAK77_RS07525 17eb10a2383bbc6e9ef41ab722041ff1 743 SUPERFAMILY SSF53706 3 477 1.44E-111 T 06-07-2017 CAK77_RS07525 17eb10a2383bbc6e9ef41ab722041ff1 743 Gene3D G3DSA:2.20.25.90 3 61 6.7E-15 T 06-07-2017 CAK77_RS07525 17eb10a2383bbc6e9ef41ab722041ff1 743 Gene3D G3DSA:2.40.40.20 606 737 1.2E-18 T 06-07-2017 CAK77_RS11850 5585db88965e2d0d2cac76a28d7011ca 123 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 4 115 3.4E-22 T 06-07-2017 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CAK77_RS11850 5585db88965e2d0d2cac76a28d7011ca 123 TIGRFAM TIGR00494 crcB: protein CrcB 5 123 4.1E-25 T 06-07-2017 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CAK77_RS11850 5585db88965e2d0d2cac76a28d7011ca 123 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 3 120 17.205 T 06-07-2017 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CAK77_RS15765 231b554a5a332f4592bf8415235825d9 270 Pfam PF08445 FR47-like protein 201 261 5.2E-10 T 06-07-2017 IPR013653 FR47-like GO:0016747 CAK77_RS15765 231b554a5a332f4592bf8415235825d9 270 Gene3D G3DSA:3.40.630.30 129 264 5.2E-17 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS15765 231b554a5a332f4592bf8415235825d9 270 Pfam PF13312 Domain of unknown function (DUF4081) 40 142 5.4E-35 T 06-07-2017 IPR025289 Domain of unknown function DUF4081 CAK77_RS15765 231b554a5a332f4592bf8415235825d9 270 SUPERFAMILY SSF55729 128 263 8.68E-16 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS15765 231b554a5a332f4592bf8415235825d9 270 PIRSF PIRSF021603 1 269 7.6E-114 T 06-07-2017 IPR016794 Uncharacterised conserved protein UCP21603, acetyltransferase-like CAK77_RS15790 3d27184480cce47cc8c59d313d9788ca 156 SUPERFAMILY SSF47598 98 142 2.06E-8 T 06-07-2017 IPR010985 Ribbon-helix-helix GO:0006355 CAK77_RS15790 3d27184480cce47cc8c59d313d9788ca 156 Pfam PF05534 HicB family 102 131 9.1E-5 T 06-07-2017 IPR008651 Uncharacterised protein family HicB CAK77_RS15790 3d27184480cce47cc8c59d313d9788ca 156 Gene3D G3DSA:1.10.1220.10 100 139 1.9E-7 T 06-07-2017 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CAK77_RS12145 f4477521726520f910d0259419b92eec 479 Pfam PF00012 Hsp70 protein 153 335 1.5E-16 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CAK77_RS12145 f4477521726520f910d0259419b92eec 479 SUPERFAMILY SSF53067 155 335 2.59E-30 T 06-07-2017 CAK77_RS12145 f4477521726520f910d0259419b92eec 479 Gene3D G3DSA:3.90.640.10 193 264 1.7E-5 T 06-07-2017 CAK77_RS12145 f4477521726520f910d0259419b92eec 479 Gene3D G3DSA:3.30.420.40 99 164 9.0E-4 T 06-07-2017 CAK77_RS12145 f4477521726520f910d0259419b92eec 479 Gene3D G3DSA:3.30.420.40 165 192 1.1E-6 T 06-07-2017 CAK77_RS12145 f4477521726520f910d0259419b92eec 479 Gene3D G3DSA:3.30.420.40 274 311 1.1E-6 T 06-07-2017 CAK77_RS10075 fc13f3617651eded2d3387739cf54380 321 ProSitePatterns PS01173 Lipolytic enzymes "G-D-X-G" family, putative histidine active site. 91 107 - T 06-07-2017 IPR002168 Lipase, GDXG, putative histidine active site GO:0008152|GO:0016787 Reactome: R-HSA-163560 CAK77_RS10075 fc13f3617651eded2d3387739cf54380 321 ProSitePatterns PS01174 Lipolytic enzymes "G-D-X-G" family, putative serine active site. 162 174 - T 06-07-2017 IPR033140 Lipase, GDXG, putative serine active site CAK77_RS10075 fc13f3617651eded2d3387739cf54380 321 SUPERFAMILY SSF53474 53 316 1.91E-54 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS10075 fc13f3617651eded2d3387739cf54380 321 Pfam PF07859 alpha/beta hydrolase fold 91 295 1.5E-56 T 06-07-2017 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CAK77_RS10075 fc13f3617651eded2d3387739cf54380 321 Gene3D G3DSA:3.40.50.1820 27 316 1.0E-67 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS06650 25eb52fbdbbb2ff064857161fa94845a 189 SUPERFAMILY SSF46785 3 173 2.56E-35 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS06650 25eb52fbdbbb2ff064857161fa94845a 189 Pfam PF03551 Transcriptional regulator PadR-like family 7 80 2.4E-12 T 06-07-2017 IPR005149 Transcription regulator PadR, N-terminal CAK77_RS06650 25eb52fbdbbb2ff064857161fa94845a 189 Gene3D G3DSA:1.10.10.10 3 85 4.8E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS06650 25eb52fbdbbb2ff064857161fa94845a 189 Pfam PF10400 Virulence activator alpha C-term 93 173 1.8E-19 T 06-07-2017 IPR018309 Transcription regulator PadR, C-terminal CAK77_RS17445 13e53f24cb45f44f9c7bdf010a701fc6 493 Pfam PF01494 FAD binding domain 5 328 2.7E-77 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 CAK77_RS17445 13e53f24cb45f44f9c7bdf010a701fc6 493 Gene3D G3DSA:3.50.50.60 5 170 1.3E-56 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS17445 13e53f24cb45f44f9c7bdf010a701fc6 493 Gene3D G3DSA:3.50.50.60 251 332 1.3E-56 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS17445 13e53f24cb45f44f9c7bdf010a701fc6 493 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 1.5E-45 T 06-07-2017 CAK77_RS17445 13e53f24cb45f44f9c7bdf010a701fc6 493 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 144 159 1.5E-45 T 06-07-2017 CAK77_RS17445 13e53f24cb45f44f9c7bdf010a701fc6 493 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 314 330 1.5E-45 T 06-07-2017 CAK77_RS17445 13e53f24cb45f44f9c7bdf010a701fc6 493 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 296 314 1.5E-45 T 06-07-2017 CAK77_RS17445 13e53f24cb45f44f9c7bdf010a701fc6 493 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 263 278 1.5E-45 T 06-07-2017 CAK77_RS17445 13e53f24cb45f44f9c7bdf010a701fc6 493 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 278 294 1.5E-45 T 06-07-2017 CAK77_RS17445 13e53f24cb45f44f9c7bdf010a701fc6 493 SUPERFAMILY SSF51905 6 165 6.64E-61 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS17445 13e53f24cb45f44f9c7bdf010a701fc6 493 SUPERFAMILY SSF51905 250 349 6.64E-61 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS03065 ddf2da14691135c9d96489a5470a3135 141 Pfam PF12120 Rifampin ADP-ribosyl transferase 15 113 8.6E-48 T 06-07-2017 IPR021975 DNA/RNA tunnel of bacterial DNA dependent RNA polymerase CAK77_RS14335 00fd0a49b3b33ec3ffd498b37ec794f8 803 SUPERFAMILY SSF52518 396 599 1.71E-22 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK77_RS14335 00fd0a49b3b33ec3ffd498b37ec794f8 803 ProSitePatterns PS60002 Phosphoketolase signature 1. 149 155 - T 06-07-2017 IPR019790 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, conserved site GO:0005975|GO:0016832 CAK77_RS14335 00fd0a49b3b33ec3ffd498b37ec794f8 803 Pfam PF09363 XFP C-terminal domain 593 796 2.0E-82 T 06-07-2017 IPR018969 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, C-terminal GO:0005975|GO:0016832 CAK77_RS14335 00fd0a49b3b33ec3ffd498b37ec794f8 803 Hamap MF_01403 Probable phosphoketolase. 10 798 38.461 T 06-07-2017 IPR023962 Probable phosphoketolase CAK77_RS14335 00fd0a49b3b33ec3ffd498b37ec794f8 803 Pfam PF09364 XFP N-terminal domain 14 391 8.9E-173 T 06-07-2017 IPR018970 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, N-terminal CAK77_RS14335 00fd0a49b3b33ec3ffd498b37ec794f8 803 Pfam PF03894 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase 406 582 8.5E-87 T 06-07-2017 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 CAK77_RS14335 00fd0a49b3b33ec3ffd498b37ec794f8 803 ProSitePatterns PS60003 Phosphoketolase signature 2. 162 180 - T 06-07-2017 IPR019789 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, thiamine diphosphate binding site GO:0005975|GO:0016832 CAK77_RS14335 00fd0a49b3b33ec3ffd498b37ec794f8 803 Gene3D G3DSA:3.40.50.970 48 271 1.8E-17 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK77_RS14335 00fd0a49b3b33ec3ffd498b37ec794f8 803 PIRSF PIRSF017245 1 798 0.0 T 06-07-2017 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 CAK77_RS14335 00fd0a49b3b33ec3ffd498b37ec794f8 803 SUPERFAMILY SSF52518 10 375 4.55E-68 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK77_RS12630 25af605999c18aee1f0f03469195b45e 345 Pfam PF05621 Bacterial TniB protein 46 309 3.6E-23 T 06-07-2017 IPR008868 Bacterial TniB CAK77_RS12630 25af605999c18aee1f0f03469195b45e 345 SUPERFAMILY SSF52540 74 107 3.74E-7 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS12630 25af605999c18aee1f0f03469195b45e 345 SUPERFAMILY SSF52540 135 314 3.74E-7 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS12630 25af605999c18aee1f0f03469195b45e 345 Gene3D G3DSA:3.40.50.300 79 200 5.3E-6 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS22625 afccdbdfcdc49038afc12a99bf0d4065 238 Gene3D G3DSA:1.10.357.10 11 199 5.8E-28 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS22625 afccdbdfcdc49038afc12a99bf0d4065 238 SUPERFAMILY SSF48498 93 199 3.71E-9 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS22625 afccdbdfcdc49038afc12a99bf0d4065 238 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 66 3.3E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS22625 afccdbdfcdc49038afc12a99bf0d4065 238 SUPERFAMILY SSF46689 13 91 4.34E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS19940 650e4fc65e4cf57c10f8ac9f62051017 123 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 21 105 3.5E-22 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CAK77_RS19940 650e4fc65e4cf57c10f8ac9f62051017 123 Pfam PF04075 Domain of unknown function (DUF385) 27 103 1.7E-4 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CAK77_RS11450 185039fcd03cd3df47ca147489d5c3f3 205 Hamap MF_00527 Putative 3-methyladenine DNA glycosylase. 3 188 28.555 T 06-07-2017 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CAK77_RS11450 185039fcd03cd3df47ca147489d5c3f3 205 Gene3D G3DSA:3.10.300.10 4 196 4.6E-53 T 06-07-2017 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CAK77_RS11450 185039fcd03cd3df47ca147489d5c3f3 205 Pfam PF02245 Methylpurine-DNA glycosylase (MPG) 6 184 2.5E-55 T 06-07-2017 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CAK77_RS11450 185039fcd03cd3df47ca147489d5c3f3 205 SUPERFAMILY SSF50486 5 195 6.59E-54 T 06-07-2017 IPR011034 Formyl transferase, C-terminal-like GO:0003824 CAK77_RS11450 185039fcd03cd3df47ca147489d5c3f3 205 TIGRFAM TIGR00567 3mg: DNA-3-methyladenine glycosylase 3 188 6.1E-56 T 06-07-2017 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CAK77_RS17695 daf73e46ec0ed5a78c468546fce0a7bb 265 SUPERFAMILY SSF52540 2 252 2.06E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS17695 daf73e46ec0ed5a78c468546fce0a7bb 265 Gene3D G3DSA:3.40.50.300 2 252 1.3E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS17695 daf73e46ec0ed5a78c468546fce0a7bb 265 Pfam PF13614 AAA domain 2 176 4.0E-57 T 06-07-2017 IPR025669 AAA domain CAK77_RS08135 d9bb6ac98138d3206a454e5c8ad83a7f 273 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 22 272 1.7E-50 T 06-07-2017 IPR003786 Protein FdhD GO:0016783 CAK77_RS08135 d9bb6ac98138d3206a454e5c8ad83a7f 273 SUPERFAMILY SSF53927 7 272 7.22E-77 T 06-07-2017 IPR016193 Cytidine deaminase-like GO:0003824 CAK77_RS08135 d9bb6ac98138d3206a454e5c8ad83a7f 273 Pfam PF02634 FdhD/NarQ family 26 272 1.9E-81 T 06-07-2017 IPR003786 Protein FdhD GO:0016783 CAK77_RS08135 d9bb6ac98138d3206a454e5c8ad83a7f 273 PIRSF PIRSF015626 2 273 7.5E-85 T 06-07-2017 IPR003786 Protein FdhD GO:0016783 CAK77_RS08135 d9bb6ac98138d3206a454e5c8ad83a7f 273 Hamap MF_00187 Sulfurtransferase FdhD [fdhD]. 2 273 33.163 T 06-07-2017 IPR003786 Protein FdhD GO:0016783 CAK77_RS08135 d9bb6ac98138d3206a454e5c8ad83a7f 273 Gene3D G3DSA:3.10.20.10 28 120 7.0E-28 T 06-07-2017 CAK77_RS08135 d9bb6ac98138d3206a454e5c8ad83a7f 273 Gene3D G3DSA:3.40.140.10 138 272 1.5E-54 T 06-07-2017 CAK77_RS20775 fde10ef6a777ce767e4beb37aaf361eb 503 Pfam PF00982 Glycosyltransferase family 20 19 482 3.3E-157 T 06-07-2017 IPR001830 Glycosyl transferase, family 20 GO:0003824|GO:0005992 CAK77_RS20775 fde10ef6a777ce767e4beb37aaf361eb 503 SUPERFAMILY SSF53756 18 482 4.26E-143 T 06-07-2017 CAK77_RS20775 fde10ef6a777ce767e4beb37aaf361eb 503 Gene3D G3DSA:3.40.50.2000 269 466 1.4E-75 T 06-07-2017 CAK77_RS20775 fde10ef6a777ce767e4beb37aaf361eb 503 Gene3D G3DSA:3.40.50.2000 18 268 1.4E-83 T 06-07-2017 CAK77_RS10620 0cda5d858f0fce944c81e80bdd361fa6 491 ProSitePatterns PS00571 Amidases signature. 147 178 - T 06-07-2017 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 CAK77_RS10620 0cda5d858f0fce944c81e80bdd361fa6 491 Pfam PF01425 Amidase 28 471 1.9E-90 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAK77_RS10620 0cda5d858f0fce944c81e80bdd361fa6 491 Gene3D G3DSA:3.90.1300.10 425 488 1.5E-118 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAK77_RS10620 0cda5d858f0fce944c81e80bdd361fa6 491 Gene3D G3DSA:3.90.1300.10 5 391 1.5E-118 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAK77_RS10620 0cda5d858f0fce944c81e80bdd361fa6 491 SUPERFAMILY SSF75304 425 480 1.57E-122 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAK77_RS10620 0cda5d858f0fce944c81e80bdd361fa6 491 SUPERFAMILY SSF75304 3 389 1.57E-122 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAK77_RS09865 aeee8c873e725f0ca1e369d42c409dd5 254 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 194 3.1E-4 T 06-07-2017 CAK77_RS09865 aeee8c873e725f0ca1e369d42c409dd5 254 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 251 3.9E-59 T 06-07-2017 CAK77_RS09865 aeee8c873e725f0ca1e369d42c409dd5 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 1.5E-14 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS09865 aeee8c873e725f0ca1e369d42c409dd5 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 1.5E-14 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS09865 aeee8c873e725f0ca1e369d42c409dd5 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 1.5E-14 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS09865 aeee8c873e725f0ca1e369d42c409dd5 254 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK77_RS09865 aeee8c873e725f0ca1e369d42c409dd5 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 6.2E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS09865 aeee8c873e725f0ca1e369d42c409dd5 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 6.2E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS09865 aeee8c873e725f0ca1e369d42c409dd5 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 6.2E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS09865 aeee8c873e725f0ca1e369d42c409dd5 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 6.2E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS09865 aeee8c873e725f0ca1e369d42c409dd5 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 6.2E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS09865 aeee8c873e725f0ca1e369d42c409dd5 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 6.2E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS09865 aeee8c873e725f0ca1e369d42c409dd5 254 Gene3D G3DSA:3.40.50.720 5 253 1.3E-81 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS09865 aeee8c873e725f0ca1e369d42c409dd5 254 SUPERFAMILY SSF51735 7 252 1.13E-77 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS20990 49e139deb05508598c046ffd8dad9a9d 299 Gene3D G3DSA:3.40.630.30 158 289 6.3E-17 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS20990 49e139deb05508598c046ffd8dad9a9d 299 SUPERFAMILY SSF55729 185 289 2.8E-15 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS20990 49e139deb05508598c046ffd8dad9a9d 299 Pfam PF00583 Acetyltransferase (GNAT) family 207 282 5.7E-9 T 06-07-2017 IPR000182 GNAT domain GO:0008080 CAK77_RS16670 70e870e73b3fb7af469abe4aeeb3e3d1 343 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 15 332 5.5E-38 T 06-07-2017 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CAK77_RS16670 70e870e73b3fb7af469abe4aeeb3e3d1 343 Gene3D G3DSA:3.20.20.210 110 324 1.4E-12 T 06-07-2017 CAK77_RS16670 70e870e73b3fb7af469abe4aeeb3e3d1 343 SUPERFAMILY SSF51726 22 332 5.23E-27 T 06-07-2017 CAK77_RS10030 096ac24ac3ba8df28f40297f953f7a9f 679 Gene3D G3DSA:2.40.50.100 596 665 4.4E-23 T 06-07-2017 CAK77_RS10030 096ac24ac3ba8df28f40297f953f7a9f 679 Pfam PF00289 Biotin carboxylase, N-terminal domain 6 113 1.4E-43 T 06-07-2017 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAK77_RS10030 096ac24ac3ba8df28f40297f953f7a9f 679 SUPERFAMILY SSF51246 340 453 4.97E-37 T 06-07-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAK77_RS10030 096ac24ac3ba8df28f40297f953f7a9f 679 SUPERFAMILY SSF52440 4 117 2.37E-48 T 06-07-2017 IPR016185 Pre-ATP-grasp domain CAK77_RS10030 096ac24ac3ba8df28f40297f953f7a9f 679 Pfam PF02785 Biotin carboxylase C-terminal domain 345 452 9.9E-35 T 06-07-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAK77_RS10030 096ac24ac3ba8df28f40297f953f7a9f 679 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 120 332 6.3E-76 T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CAK77_RS10030 096ac24ac3ba8df28f40297f953f7a9f 679 SUPERFAMILY SSF51230 592 665 9.29E-21 T 06-07-2017 IPR011053 Single hybrid motif CAK77_RS10030 096ac24ac3ba8df28f40297f953f7a9f 679 SMART SM00878 345 451 1.7E-49 T 06-07-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAK77_RS10030 096ac24ac3ba8df28f40297f953f7a9f 679 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 157 171 - T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CAK77_RS10030 096ac24ac3ba8df28f40297f953f7a9f 679 Gene3D G3DSA:3.30.470.20 208 453 5.9E-95 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAK77_RS10030 096ac24ac3ba8df28f40297f953f7a9f 679 SUPERFAMILY SSF56059 87 354 4.21E-68 T 06-07-2017 CAK77_RS10030 096ac24ac3ba8df28f40297f953f7a9f 679 Pfam PF00364 Biotin-requiring enzyme 599 663 2.0E-16 T 06-07-2017 IPR000089 Biotin/lipoyl attachment CAK77_RS10030 096ac24ac3ba8df28f40297f953f7a9f 679 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 295 302 - T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CAK77_RS10030 096ac24ac3ba8df28f40297f953f7a9f 679 Gene3D G3DSA:3.40.50.20 6 133 2.7E-50 T 06-07-2017 IPR016185 Pre-ATP-grasp domain CAK77_RS10030 096ac24ac3ba8df28f40297f953f7a9f 679 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 621 638 - T 06-07-2017 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAK77_RS10030 096ac24ac3ba8df28f40297f953f7a9f 679 Gene3D G3DSA:3.30.1490.20 134 206 5.7E-27 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CAK77_RS24150 cf4e2932695197ca3826b381974282a4 349 SUPERFAMILY SSF56112 12 327 6.56E-54 T 06-07-2017 IPR011009 Protein kinase-like domain CAK77_RS24150 cf4e2932695197ca3826b381974282a4 349 Pfam PF01636 Phosphotransferase enzyme family 34 279 9.7E-44 T 06-07-2017 IPR002575 Aminoglycoside phosphotransferase CAK77_RS24150 cf4e2932695197ca3826b381974282a4 349 Gene3D G3DSA:3.90.1200.10 141 325 1.3E-30 T 06-07-2017 CAK77_RS14755 2242518ed54bece352195289fb9344f9 302 PIRSF PIRSF007580 5 289 6.2E-63 T 06-07-2017 IPR016516 Uncharacterised conserved protein UCP07580 CAK77_RS14755 2242518ed54bece352195289fb9344f9 302 Pfam PF10118 Predicted metal-dependent hydrolase 18 271 8.4E-75 T 06-07-2017 IPR016516 Uncharacterised conserved protein UCP07580 CAK77_RS09620 20f591dcb3191dcc56084cf89a61f0a7 131 SUPERFAMILY SSF55961 6 82 8.09E-7 T 06-07-2017 CAK77_RS09620 20f591dcb3191dcc56084cf89a61f0a7 131 Gene3D G3DSA:3.30.530.20 4 68 2.8E-4 T 06-07-2017 IPR023393 START-like domain CAK77_RS15410 9b996a6466f53c79801c6273c9e435cd 245 SUPERFAMILY SSF51735 4 133 7.13E-34 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS15410 9b996a6466f53c79801c6273c9e435cd 245 PIRSF PIRSF000161 2 245 2.4E-64 T 06-07-2017 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAK77_RS15410 9b996a6466f53c79801c6273c9e435cd 245 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 128 145 - T 06-07-2017 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAK77_RS15410 9b996a6466f53c79801c6273c9e435cd 245 SUPERFAMILY SSF55347 107 215 1.81E-41 T 06-07-2017 CAK77_RS15410 9b996a6466f53c79801c6273c9e435cd 245 Gene3D G3DSA:3.30.360.10 123 212 8.7E-34 T 06-07-2017 CAK77_RS15410 9b996a6466f53c79801c6273c9e435cd 245 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 44 243 1.3E-58 T 06-07-2017 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAK77_RS15410 9b996a6466f53c79801c6273c9e435cd 245 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 4 244 29.278 T 06-07-2017 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAK77_RS15410 9b996a6466f53c79801c6273c9e435cd 245 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 109 235 2.4E-31 T 06-07-2017 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAK77_RS15410 9b996a6466f53c79801c6273c9e435cd 245 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 7 106 5.3E-24 T 06-07-2017 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAK77_RS15410 9b996a6466f53c79801c6273c9e435cd 245 Gene3D G3DSA:3.40.50.720 4 122 9.2E-42 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS08535 5141b7931b479ed5cec2451db3599eaf 261 SUPERFAMILY SSF57863 82 232 5.49E-36 T 06-07-2017 CAK77_RS08535 5141b7931b479ed5cec2451db3599eaf 261 Pfam PF02565 Recombination protein O C terminal 85 237 5.1E-29 T 06-07-2017 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 CAK77_RS08535 5141b7931b479ed5cec2451db3599eaf 261 Hamap MF_00201 DNA repair protein RecO [recO]. 2 243 25.134 T 06-07-2017 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 CAK77_RS08535 5141b7931b479ed5cec2451db3599eaf 261 Pfam PF11967 Recombination protein O N terminal 1 79 1.3E-27 T 06-07-2017 IPR022572 DNA replication/recombination mediator RecO, N-terminal CAK77_RS08535 5141b7931b479ed5cec2451db3599eaf 261 Gene3D G3DSA:2.40.50.140 1 80 5.5E-40 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS08535 5141b7931b479ed5cec2451db3599eaf 261 TIGRFAM TIGR00613 reco: DNA repair protein RecO 5 228 2.5E-31 T 06-07-2017 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 CAK77_RS08535 5141b7931b479ed5cec2451db3599eaf 261 SUPERFAMILY SSF50249 1 79 2.23E-21 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS12475 b2afcbacca9e90bb2aa9bb5e6b92431a 335 Gene3D G3DSA:3.40.109.10 168 169 1.7E-25 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CAK77_RS12475 b2afcbacca9e90bb2aa9bb5e6b92431a 335 Gene3D G3DSA:3.40.109.10 217 332 1.7E-25 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CAK77_RS12475 b2afcbacca9e90bb2aa9bb5e6b92431a 335 Gene3D G3DSA:3.40.109.10 9 76 1.7E-25 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CAK77_RS12475 b2afcbacca9e90bb2aa9bb5e6b92431a 335 SUPERFAMILY SSF55469 259 331 3.49E-16 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CAK77_RS12475 b2afcbacca9e90bb2aa9bb5e6b92431a 335 SUPERFAMILY SSF55469 10 141 3.49E-16 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CAK77_RS21855 8ca918783da1a2e1d7a5086ca4a86e66 628 SUPERFAMILY SSF56801 23 620 5.23E-113 T 06-07-2017 CAK77_RS21855 8ca918783da1a2e1d7a5086ca4a86e66 628 Gene3D G3DSA:3.40.50.980 83 242 4.4E-26 T 06-07-2017 CAK77_RS21855 8ca918783da1a2e1d7a5086ca4a86e66 628 Pfam PF00501 AMP-binding enzyme 90 498 2.1E-45 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK77_RS21855 8ca918783da1a2e1d7a5086ca4a86e66 628 Gene3D G3DSA:3.30.300.30 497 587 6.4E-10 T 06-07-2017 CAK77_RS21855 8ca918783da1a2e1d7a5086ca4a86e66 628 Gene3D G3DSA:3.40.50.980 243 393 6.8E-19 T 06-07-2017 CAK77_RS21855 8ca918783da1a2e1d7a5086ca4a86e66 628 ProSitePatterns PS00455 Putative AMP-binding domain signature. 237 248 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK77_RS17110 cdde7194b4b82008db4eb3c394c28d83 376 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 276 342 2.0E-5 T 06-07-2017 CAK77_RS17110 cdde7194b4b82008db4eb3c394c28d83 376 Pfam PF03601 Conserved hypothetical protein 698 31 348 6.3E-92 T 06-07-2017 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 CAK77_RS16545 4245e408c910c3f98451f63a2c087b2f 491 Gene3D G3DSA:3.40.605.10 7 261 5.8E-96 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAK77_RS16545 4245e408c910c3f98451f63a2c087b2f 491 SUPERFAMILY SSF53720 6 472 4.45E-161 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAK77_RS16545 4245e408c910c3f98451f63a2c087b2f 491 Pfam PF00171 Aldehyde dehydrogenase family 17 471 4.4E-169 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAK77_RS16545 4245e408c910c3f98451f63a2c087b2f 491 Gene3D G3DSA:3.40.309.10 262 446 8.6E-66 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAK77_RS16545 4245e408c910c3f98451f63a2c087b2f 491 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 247 254 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CAK77_RS08150 a42fe9077f0d4489f18daa47adf81b8f 368 Gene3D G3DSA:3.40.50.970 314 340 4.5E-80 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK77_RS08150 a42fe9077f0d4489f18daa47adf81b8f 368 Gene3D G3DSA:3.40.50.970 49 270 4.5E-80 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK77_RS08150 a42fe9077f0d4489f18daa47adf81b8f 368 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 83 230 1.4E-29 T 06-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CAK77_RS08150 a42fe9077f0d4489f18daa47adf81b8f 368 SUPERFAMILY SSF52518 37 367 6.61E-83 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK77_RS16410 8a4eaf90bbddfb6613c761479601c33b 165 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 13 99 5.1E-20 T 06-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAK77_RS16410 8a4eaf90bbddfb6613c761479601c33b 165 SUPERFAMILY SSF50475 10 148 3.74E-37 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS16410 8a4eaf90bbddfb6613c761479601c33b 165 Gene3D G3DSA:2.30.110.10 11 149 1.9E-36 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS16410 8a4eaf90bbddfb6613c761479601c33b 165 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 17 143 4.7E-29 T 06-07-2017 IPR019920 F420-binding domain, putative CAK77_RS04555 327647eb9d0c8bf3047b7110e29b7193 628 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 70 228 6.2E-36 T 06-07-2017 CAK77_RS20485 7c9427665315e5c8d1998cea6487af2d 219 ProSitePatterns PS01081 TetR-type HTH domain signature. 33 64 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CAK77_RS20485 7c9427665315e5c8d1998cea6487af2d 219 Gene3D G3DSA:1.10.357.10 12 188 4.2E-26 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS20485 7c9427665315e5c8d1998cea6487af2d 219 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 67 9.3E-17 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS20485 7c9427665315e5c8d1998cea6487af2d 219 SUPERFAMILY SSF46689 10 86 1.35E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS20485 7c9427665315e5c8d1998cea6487af2d 219 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 3.2E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS20485 7c9427665315e5c8d1998cea6487af2d 219 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 3.2E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS16230 fe032a0b1b535a98cf7063f287af2f6f 157 Pfam PF05481 Mycobacterium 19 kDa lipoprotein antigen 7 153 2.5E-36 T 06-07-2017 IPR008691 19kDa lipoprotein antigen GO:0016020 CAK77_RS04605 272b34af49a8eaa6b452f03732a1c80d 1002 Pfam PF03176 MMPL family 44 371 1.9E-93 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 CAK77_RS04605 272b34af49a8eaa6b452f03732a1c80d 1002 Pfam PF03176 MMPL family 658 992 2.9E-86 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 CAK77_RS04605 272b34af49a8eaa6b452f03732a1c80d 1002 SUPERFAMILY SSF82866 767 982 5.75E-27 T 06-07-2017 CAK77_RS04605 272b34af49a8eaa6b452f03732a1c80d 1002 Gene3D G3DSA:1.20.1640.10 792 984 1.5E-18 T 06-07-2017 CAK77_RS04605 272b34af49a8eaa6b452f03732a1c80d 1002 Gene3D G3DSA:1.20.1640.10 161 351 1.9E-26 T 06-07-2017 CAK77_RS04605 272b34af49a8eaa6b452f03732a1c80d 1002 SUPERFAMILY SSF82866 160 346 1.31E-28 T 06-07-2017 CAK77_RS04605 272b34af49a8eaa6b452f03732a1c80d 1002 TIGRFAM TIGR00833 actII: transport protein 10 982 5.3E-267 T 06-07-2017 IPR004707 Membrane transport protein MmpL family GO:0016021 CAK77_RS24470 5b2fe88a28674b0c372dcc4cab962156 365 SUPERFAMILY SSF47413 15 69 2.25E-8 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK77_RS24470 5b2fe88a28674b0c372dcc4cab962156 365 Pfam PF13560 Helix-turn-helix domain 18 65 7.3E-9 T 06-07-2017 CAK77_RS24470 5b2fe88a28674b0c372dcc4cab962156 365 Gene3D G3DSA:1.10.260.40 18 69 1.5E-9 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK77_RS24470 5b2fe88a28674b0c372dcc4cab962156 365 Pfam PF06114 Domain of unknown function (DUF955) 163 279 7.3E-9 T 06-07-2017 IPR010359 HTH domain, IrrE-type CAK77_RS24470 5b2fe88a28674b0c372dcc4cab962156 365 SMART SM00530 14 69 7.9E-8 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAK77_RS18830 38159869be1e2bdac4ca5853b6278e9e 73 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 4 72 6.9E-38 T 06-07-2017 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 CAK77_RS18830 38159869be1e2bdac4ca5853b6278e9e 73 SUPERFAMILY SSF50249 4 72 1.47E-26 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS18830 38159869be1e2bdac4ca5853b6278e9e 73 Gene3D G3DSA:2.40.50.140 2 73 6.0E-39 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS18830 38159869be1e2bdac4ca5853b6278e9e 73 Pfam PF01176 Translation initiation factor 1A / IF-1 8 71 1.2E-28 T 06-07-2017 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 CAK77_RS18830 38159869be1e2bdac4ca5853b6278e9e 73 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 2 73 26.479 T 06-07-2017 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 CAK77_RS08330 509c968c86c75a7574e328f0141af3bd 316 Gene3D G3DSA:3.40.50.300 4 114 9.1E-8 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS08330 509c968c86c75a7574e328f0141af3bd 316 Gene3D G3DSA:1.10.8.60 129 210 1.4E-5 T 06-07-2017 CAK77_RS08330 509c968c86c75a7574e328f0141af3bd 316 SUPERFAMILY SSF48019 195 311 6.29E-12 T 06-07-2017 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 CAK77_RS08330 509c968c86c75a7574e328f0141af3bd 316 Pfam PF06144 DNA polymerase III, delta subunit 6 166 4.3E-9 T 06-07-2017 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 CAK77_RS04365 4721b8cd21c50ad19323c3ac9675b339 132 Pfam PF10947 Protein of unknown function (DUF2628) 11 120 9.6E-26 T 06-07-2017 IPR024399 Protein of unknown function DUF2628 CAK77_RS04365 4721b8cd21c50ad19323c3ac9675b339 132 ProDom PD031864 YIGF SIMILAR ESCHERICHIA COLI MEMBRANE XCC4223 XAC4357 XAC2195 10 126 7.0E-11 T 06-07-2017 CAK77_RS14140 283d377de1d813869b0707ea0aafac3b 193 Pfam PF01174 SNO glutamine amidotransferase family 7 190 7.0E-60 T 06-07-2017 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CAK77_RS14140 283d377de1d813869b0707ea0aafac3b 193 Hamap MF_01615 Pyridoxal 5'-phosphate synthase subunit PdxT [pdxT]. 5 189 38.333 T 06-07-2017 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CAK77_RS14140 283d377de1d813869b0707ea0aafac3b 193 TIGRFAM TIGR03800 PLP_synth_Pdx2: pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2 5 188 7.1E-74 T 06-07-2017 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CAK77_RS14140 283d377de1d813869b0707ea0aafac3b 193 Gene3D G3DSA:3.40.50.880 3 191 2.8E-73 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAK77_RS14140 283d377de1d813869b0707ea0aafac3b 193 PIRSF PIRSF005639 2 193 8.9E-72 T 06-07-2017 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CAK77_RS14140 283d377de1d813869b0707ea0aafac3b 193 ProSitePatterns PS01236 PdxT/SNO family family signature. 42 52 - T 06-07-2017 IPR021196 PdxT/SNO family, conserved site KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CAK77_RS14140 283d377de1d813869b0707ea0aafac3b 193 SUPERFAMILY SSF52317 4 190 9.31E-49 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAK77_RS21280 d072ced806fca2d0298faabe3125e95f 105 Pfam PF02148 Zn-finger in ubiquitin-hydrolases and other protein 40 101 1.1E-9 T 06-07-2017 IPR001607 Zinc finger, UBP-type GO:0008270 CAK77_RS21280 d072ced806fca2d0298faabe3125e95f 105 SUPERFAMILY SSF57850 21 102 7.89E-22 T 06-07-2017 CAK77_RS21280 d072ced806fca2d0298faabe3125e95f 105 Gene3D G3DSA:3.30.40.10 21 102 3.1E-20 T 06-07-2017 IPR013083 Zinc finger, RING/FYVE/PHD-type CAK77_RS11600 a17d749bee844472af426c9647858ab9 487 SUPERFAMILY SSF56425 296 424 4.19E-25 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK77_RS11600 a17d749bee844472af426c9647858ab9 487 Pfam PF00890 FAD binding domain 22 451 2.2E-53 T 06-07-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK77_RS11600 a17d749bee844472af426c9647858ab9 487 SUPERFAMILY SSF51905 423 482 1.37E-41 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS11600 a17d749bee844472af426c9647858ab9 487 SUPERFAMILY SSF51905 182 298 1.37E-41 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS11600 a17d749bee844472af426c9647858ab9 487 SUPERFAMILY SSF51905 10 133 1.37E-41 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS11600 a17d749bee844472af426c9647858ab9 487 Gene3D G3DSA:3.50.50.60 420 483 1.8E-69 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS11600 a17d749bee844472af426c9647858ab9 487 Gene3D G3DSA:3.50.50.60 12 280 1.8E-69 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS11600 a17d749bee844472af426c9647858ab9 487 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 22 44 4.8E-7 T 06-07-2017 CAK77_RS11600 a17d749bee844472af426c9647858ab9 487 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 440 455 4.8E-7 T 06-07-2017 CAK77_RS11600 a17d749bee844472af426c9647858ab9 487 Gene3D G3DSA:3.90.700.10 297 410 4.6E-21 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK77_RS02320 2047229be14fbb17ce83065b217ac82e 215 ProSitePatterns PS00194 Thioredoxin family active site. 103 121 - T 06-07-2017 IPR017937 Thioredoxin, conserved site GO:0045454 CAK77_RS02320 2047229be14fbb17ce83065b217ac82e 215 Pfam PF08534 Redoxin 97 191 1.3E-10 T 06-07-2017 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 CAK77_RS02320 2047229be14fbb17ce83065b217ac82e 215 SUPERFAMILY SSF52833 96 210 2.84E-19 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK77_RS02320 2047229be14fbb17ce83065b217ac82e 215 Gene3D G3DSA:3.40.30.10 10 34 2.2E-27 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK77_RS02320 2047229be14fbb17ce83065b217ac82e 215 Gene3D G3DSA:3.40.30.10 71 212 2.2E-27 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK77_RS07105 fb5a43afa4e5abccb78c71bb076e0e57 172 ProDom PD103646 LIPOPROTEIN LPRB MEMBRANE PRECURSOR PALMITATE SIGNAL 36 167 0.001 T 06-07-2017 CAK77_RS07105 fb5a43afa4e5abccb78c71bb076e0e57 172 Pfam PF12079 Protein of unknown function (DUF3558) 13 170 4.4E-24 T 06-07-2017 IPR024520 Protein of unknown function DUF3558 CAK77_RS20230 629503d3c5849de02b677e2cbc072195 179 Gene3D G3DSA:3.30.530.20 26 155 1.3E-6 T 06-07-2017 IPR023393 START-like domain CAK77_RS20230 629503d3c5849de02b677e2cbc072195 179 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 24 170 7.5E-10 T 06-07-2017 IPR019587 Polyketide cyclase/dehydrase CAK77_RS20230 629503d3c5849de02b677e2cbc072195 179 SUPERFAMILY SSF55961 24 170 3.54E-13 T 06-07-2017 CAK77_RS05400 57699ded5b07e909f1bca32cb8633a78 57 Pfam PF01783 Ribosomal L32p protein family 2 46 3.0E-13 T 06-07-2017 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS05400 57699ded5b07e909f1bca32cb8633a78 57 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 53 12.736 T 06-07-2017 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS05400 57699ded5b07e909f1bca32cb8633a78 57 SUPERFAMILY SSF57829 1 37 1.65E-8 T 06-07-2017 IPR011332 Zinc-binding ribosomal protein GO:0006412 CAK77_RS05400 57699ded5b07e909f1bca32cb8633a78 57 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 48 3.7E-13 T 06-07-2017 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS10540 60e842ffb4c1bd4e14c64c5b3546657f 564 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 196 307 9.0E-15 T 06-07-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CAK77_RS10540 60e842ffb4c1bd4e14c64c5b3546657f 564 Gene3D G3DSA:3.40.50.970 2 181 2.0E-44 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK77_RS10540 60e842ffb4c1bd4e14c64c5b3546657f 564 SUPERFAMILY SSF52518 350 533 1.43E-40 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK77_RS10540 60e842ffb4c1bd4e14c64c5b3546657f 564 Gene3D G3DSA:3.40.50.1220 194 328 1.2E-15 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAK77_RS10540 60e842ffb4c1bd4e14c64c5b3546657f 564 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 2 171 1.1E-39 T 06-07-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CAK77_RS10540 60e842ffb4c1bd4e14c64c5b3546657f 564 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 374 522 4.0E-29 T 06-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CAK77_RS10540 60e842ffb4c1bd4e14c64c5b3546657f 564 SUPERFAMILY SSF52518 3 181 5.05E-40 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK77_RS10540 60e842ffb4c1bd4e14c64c5b3546657f 564 SUPERFAMILY SSF52467 192 331 1.5E-16 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAK77_RS10540 60e842ffb4c1bd4e14c64c5b3546657f 564 Gene3D G3DSA:3.40.50.970 345 534 3.7E-45 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK77_RS15490 c0f6caae764a6b857fc26cae16f1b7da 298 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 9 221 1.3E-68 T 06-07-2017 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAK77_RS15490 c0f6caae764a6b857fc26cae16f1b7da 298 SUPERFAMILY SSF88697 239 295 7.45E-12 T 06-07-2017 IPR015947 PUA-like domain CAK77_RS15490 c0f6caae764a6b857fc26cae16f1b7da 298 SUPERFAMILY SSF55120 9 224 5.44E-74 T 06-07-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAK77_RS15490 c0f6caae764a6b857fc26cae16f1b7da 298 Pfam PF09142 tRNA Pseudouridine synthase II, C terminal 239 294 3.6E-19 T 06-07-2017 IPR015225 tRNA pseudouridine synthase II, TruB, subfamily 2, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAK77_RS15490 c0f6caae764a6b857fc26cae16f1b7da 298 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 183 226 4.5E-11 T 06-07-2017 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 CAK77_RS15490 c0f6caae764a6b857fc26cae16f1b7da 298 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 7 293 17.345 T 06-07-2017 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAK77_RS15490 c0f6caae764a6b857fc26cae16f1b7da 298 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 29 182 1.1E-53 T 06-07-2017 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 CAK77_RS10580 d6c7b88058be47139044bf7715b12527 260 TIGRFAM TIGR03691 20S_bact_alpha: proteasome, alpha subunit 1 232 5.2E-106 T 06-07-2017 IPR022296 Proteasome, alpha subunit, bacterial GO:0004298|GO:0019773|GO:0051603 CAK77_RS10580 d6c7b88058be47139044bf7715b12527 260 Pfam PF00227 Proteasome subunit 25 198 8.4E-34 T 06-07-2017 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5687128|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-983168 CAK77_RS10580 d6c7b88058be47139044bf7715b12527 260 Gene3D G3DSA:3.60.20.10 1 235 2.6E-78 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAK77_RS10580 d6c7b88058be47139044bf7715b12527 260 SUPERFAMILY SSF56235 10 232 4.07E-45 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAK77_RS10580 d6c7b88058be47139044bf7715b12527 260 Hamap MF_00289_B Proteasome subunit alpha [prcA]. 1 236 45.11 T 06-07-2017 IPR022296 Proteasome, alpha subunit, bacterial GO:0004298|GO:0019773|GO:0051603 CAK77_RS07675 e36c94198cd2c373c06d357ec378e71e 429 SUPERFAMILY SSF50346 11 89 1.49E-9 T 06-07-2017 IPR011033 PRC-barrel-like CAK77_RS07675 e36c94198cd2c373c06d357ec378e71e 429 SUPERFAMILY SSF54631 286 412 9.73E-24 T 06-07-2017 CAK77_RS07675 e36c94198cd2c373c06d357ec378e71e 429 Gene3D G3DSA:1.25.60.10 169 281 2.1E-39 T 06-07-2017 CAK77_RS07675 e36c94198cd2c373c06d357ec378e71e 429 Pfam PF00571 CBS domain 356 411 1.8E-4 T 06-07-2017 IPR000644 CBS domain CAK77_RS07675 e36c94198cd2c373c06d357ec378e71e 429 Pfam PF00571 CBS domain 288 350 3.8E-5 T 06-07-2017 IPR000644 CBS domain CAK77_RS07675 e36c94198cd2c373c06d357ec378e71e 429 Pfam PF03448 MgtE intracellular N domain 184 284 5.4E-26 T 06-07-2017 IPR006668 Magnesium transporter, MgtE intracellular domain CAK77_RS07675 e36c94198cd2c373c06d357ec378e71e 429 SMART SM00924 184 287 3.5E-34 T 06-07-2017 IPR006668 Magnesium transporter, MgtE intracellular domain CAK77_RS07675 e36c94198cd2c373c06d357ec378e71e 429 SUPERFAMILY SSF158791 171 282 3.92E-30 T 06-07-2017 CAK77_RS07675 e36c94198cd2c373c06d357ec378e71e 429 Gene3D G3DSA:3.10.580.10 286 410 1.9E-18 T 06-07-2017 CAK77_RS00710 28067a883d2d64a454f45e00dbfe70a2 188 Gene3D G3DSA:2.60.40.1220 30 126 3.6E-25 T 06-07-2017 IPR014755 Copper resistance protein CopC/internalin, immunoglobulin-like CAK77_RS00710 28067a883d2d64a454f45e00dbfe70a2 188 Pfam PF04234 CopC domain 31 126 3.1E-23 T 06-07-2017 IPR007348 CopC domain GO:0005507|GO:0042597|GO:0046688 CAK77_RS00710 28067a883d2d64a454f45e00dbfe70a2 188 SUPERFAMILY SSF81296 30 126 1.91E-22 T 06-07-2017 IPR014756 Immunoglobulin E-set CAK77_RS24310 4ba65c244a29eabb70f37d9c92b57402 109 ProSitePatterns PS00194 Thioredoxin family active site. 26 44 - T 06-07-2017 IPR017937 Thioredoxin, conserved site GO:0045454 CAK77_RS24310 4ba65c244a29eabb70f37d9c92b57402 109 SUPERFAMILY SSF52833 4 108 3.65E-38 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK77_RS24310 4ba65c244a29eabb70f37d9c92b57402 109 PIRSF PIRSF000077 3 109 1.8E-43 T 06-07-2017 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 CAK77_RS24310 4ba65c244a29eabb70f37d9c92b57402 109 Pfam PF00085 Thioredoxin 7 105 7.5E-34 T 06-07-2017 IPR013766 Thioredoxin domain GO:0045454 CAK77_RS24310 4ba65c244a29eabb70f37d9c92b57402 109 PRINTS PR00421 Thioredoxin family signature 73 84 1.2E-8 T 06-07-2017 CAK77_RS24310 4ba65c244a29eabb70f37d9c92b57402 109 PRINTS PR00421 Thioredoxin family signature 25 33 1.2E-8 T 06-07-2017 CAK77_RS24310 4ba65c244a29eabb70f37d9c92b57402 109 PRINTS PR00421 Thioredoxin family signature 33 42 1.2E-8 T 06-07-2017 CAK77_RS24310 4ba65c244a29eabb70f37d9c92b57402 109 TIGRFAM TIGR01068 thioredoxin: thioredoxin 10 106 4.1E-39 T 06-07-2017 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 CAK77_RS24310 4ba65c244a29eabb70f37d9c92b57402 109 Gene3D G3DSA:3.40.30.10 4 104 1.8E-37 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK77_RS03240 b238ff15d832cdfd517d116c65cbd264 359 ProDom PD005364 ALDOLASE 4-HYDROXY-2-OXOVALERATE LYASE PYRUVATE 4.1.3.- PLASMID HMG-COA LYASE-LIKE TRANSFERASE HOA 292 350 2.0E-26 T 06-07-2017 IPR012425 DmpG-like communication GO:0016833|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 CAK77_RS03240 b238ff15d832cdfd517d116c65cbd264 359 Pfam PF00682 HMGL-like 23 280 1.9E-47 T 06-07-2017 IPR000891 Pyruvate carboxyltransferase GO:0003824 CAK77_RS03240 b238ff15d832cdfd517d116c65cbd264 359 Gene3D G3DSA:1.10.8.60 293 354 1.0E-27 T 06-07-2017 CAK77_RS03240 b238ff15d832cdfd517d116c65cbd264 359 Gene3D G3DSA:3.20.20.70 23 279 1.3E-47 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK77_RS03240 b238ff15d832cdfd517d116c65cbd264 359 Pfam PF07836 DmpG-like communication domain 291 351 2.3E-27 T 06-07-2017 IPR012425 DmpG-like communication GO:0016833|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 CAK77_RS03240 b238ff15d832cdfd517d116c65cbd264 359 Hamap MF_01656 4-hydroxy-2-oxovalerate aldolase [mhpE]. 1 359 168.211 T 06-07-2017 IPR017629 4-hydroxy-2-oxovalerate aldolase GO:0008701|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 CAK77_RS03240 b238ff15d832cdfd517d116c65cbd264 359 SUPERFAMILY SSF51569 22 283 6.59E-57 T 06-07-2017 CAK77_RS03240 b238ff15d832cdfd517d116c65cbd264 359 TIGRFAM TIGR03217 4OH_2_O_val_ald: 4-hydroxy-2-oxovalerate aldolase 23 353 1.6E-150 T 06-07-2017 IPR017629 4-hydroxy-2-oxovalerate aldolase GO:0008701|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 CAK77_RS03240 b238ff15d832cdfd517d116c65cbd264 359 SUPERFAMILY SSF89000 305 354 1.8E-15 T 06-07-2017 CAK77_RS15925 145ad9a7fdcdffb7f4c8c959ee1daeaf 135 Pfam PF05423 Mycobacterium membrane protein 3 133 2.1E-16 T 06-07-2017 IPR008693 Transport accessory protein MmpS CAK77_RS02880 825a7085f9c537b579f432d1dfe9a65f 266 SUPERFAMILY SSF53474 8 254 7.63E-41 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS02880 825a7085f9c537b579f432d1dfe9a65f 266 Pfam PF12697 Alpha/beta hydrolase family 21 245 6.1E-20 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS02880 825a7085f9c537b579f432d1dfe9a65f 266 Gene3D G3DSA:3.40.50.1820 11 255 3.9E-39 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS14085 4c73bbc1ede1697e3fdc266d65e371a0 424 Pfam PF02355 Protein export membrane protein 171 356 2.5E-62 T 06-07-2017 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial CAK77_RS14085 4c73bbc1ede1697e3fdc266d65e371a0 424 Gene3D G3DSA:1.20.1640.10 182 357 8.3E-19 T 06-07-2017 CAK77_RS14085 4c73bbc1ede1697e3fdc266d65e371a0 424 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 60 358 23.056 T 06-07-2017 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 CAK77_RS14085 4c73bbc1ede1697e3fdc266d65e371a0 424 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 88 347 3.3E-73 T 06-07-2017 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 CAK77_RS14085 4c73bbc1ede1697e3fdc266d65e371a0 424 SUPERFAMILY SSF82866 179 357 2.88E-30 T 06-07-2017 CAK77_RS14085 4c73bbc1ede1697e3fdc266d65e371a0 424 PRINTS PR01755 Bacterial translocase SecF protein signature 87 102 3.4E-21 T 06-07-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CAK77_RS14085 4c73bbc1ede1697e3fdc266d65e371a0 424 PRINTS PR01755 Bacterial translocase SecF protein signature 255 273 3.4E-21 T 06-07-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CAK77_RS14085 4c73bbc1ede1697e3fdc266d65e371a0 424 PRINTS PR01755 Bacterial translocase SecF protein signature 290 305 3.4E-21 T 06-07-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CAK77_RS14085 4c73bbc1ede1697e3fdc266d65e371a0 424 PRINTS PR01755 Bacterial translocase SecF protein signature 207 221 3.4E-21 T 06-07-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CAK77_RS14085 4c73bbc1ede1697e3fdc266d65e371a0 424 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 125 344 6.7E-50 T 06-07-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CAK77_RS14085 4c73bbc1ede1697e3fdc266d65e371a0 424 Pfam PF07549 SecD/SecF GG Motif 83 99 2.8E-4 T 06-07-2017 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site CAK77_RS03035 269a231a98fac99804f629784c03785f 300 SUPERFAMILY SSF54593 4 276 1.22E-36 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK77_RS03035 269a231a98fac99804f629784c03785f 300 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 143 268 2.9E-18 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CAK77_RS03035 269a231a98fac99804f629784c03785f 300 Gene3D G3DSA:3.10.180.10 4 132 5.5E-36 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK77_RS03035 269a231a98fac99804f629784c03785f 300 Gene3D G3DSA:3.10.180.10 135 296 1.1E-55 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK77_RS03035 269a231a98fac99804f629784c03785f 300 ProSitePatterns PS00082 Extradiol ring-cleavage dioxygenases signature. 246 267 - T 06-07-2017 IPR000486 Extradiol ring-cleavage dioxygenase, class I /II GO:0003824|GO:0006725|GO:0008198|GO:0055114 CAK77_RS22480 31e49da553a6af46d81198ad642a20af 523 Pfam PF02470 MlaD protein 46 124 5.9E-8 T 06-07-2017 IPR003399 Mce/MlaD CAK77_RS22480 31e49da553a6af46d81198ad642a20af 523 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 175 372 2.5E-14 T 06-07-2017 IPR024516 Mammalian cell entry, C-terminal CAK77_RS18785 f466fb784286ac06e2fcfecab199ebc5 237 Gene3D G3DSA:3.40.50.1820 37 230 2.0E-45 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS18785 f466fb784286ac06e2fcfecab199ebc5 237 SUPERFAMILY SSF53474 44 228 2.57E-29 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS18785 f466fb784286ac06e2fcfecab199ebc5 237 SMART SM01110 43 228 1.3E-63 T 06-07-2017 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 CAK77_RS18785 f466fb784286ac06e2fcfecab199ebc5 237 Pfam PF01083 Cutinase 44 228 1.7E-41 T 06-07-2017 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 CAK77_RS05930 d7c2e9caaa4474a7ae2c396d0f2250cb 160 ProDom PD076648 LIPOPROTEIN LPQV PALMITATE MEMBRANE PRECURSOR SIGNAL 79 140 2.0E-6 T 06-07-2017 IPR020377 Uncharacterised protein family LpqV CAK77_RS20260 6b013121a183dfa81d1b3141db3a1be8 333 Pfam PF07859 alpha/beta hydrolase fold 97 304 2.7E-41 T 06-07-2017 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CAK77_RS20260 6b013121a183dfa81d1b3141db3a1be8 333 SUPERFAMILY SSF53474 67 327 3.37E-43 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS20260 6b013121a183dfa81d1b3141db3a1be8 333 Gene3D G3DSA:3.40.50.1820 80 324 1.3E-46 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS18635 94392e4087a35f532498e2bb5de222d8 207 Pfam PF00814 Glycoprotease family 38 155 9.5E-26 T 06-07-2017 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CAK77_RS18635 94392e4087a35f532498e2bb5de222d8 207 SUPERFAMILY SSF53067 111 196 1.68E-10 T 06-07-2017 CAK77_RS18635 94392e4087a35f532498e2bb5de222d8 207 SUPERFAMILY SSF53067 3 105 2.42E-20 T 06-07-2017 CAK77_RS18635 94392e4087a35f532498e2bb5de222d8 207 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 4 198 1.3E-46 T 06-07-2017 IPR022496 tRNA threonylcarbamoyl adenosine modification protein YeaZ GO:0002949 CAK77_RS18635 94392e4087a35f532498e2bb5de222d8 207 Gene3D G3DSA:3.30.420.40 3 130 2.7E-32 T 06-07-2017 CAK77_RS04285 e510a3900d1dad44365bb934cb4a0ce1 363 Pfam PF02515 CoA-transferase family III 11 353 2.1E-79 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 CAK77_RS04285 e510a3900d1dad44365bb934cb4a0ce1 363 Gene3D G3DSA:3.40.50.10540 298 352 2.4E-90 T 06-07-2017 IPR023606 CoA-transferase family III domain CAK77_RS04285 e510a3900d1dad44365bb934cb4a0ce1 363 Gene3D G3DSA:3.40.50.10540 8 210 2.4E-90 T 06-07-2017 IPR023606 CoA-transferase family III domain CAK77_RS04285 e510a3900d1dad44365bb934cb4a0ce1 363 Gene3D G3DSA:3.30.1540.10 225 297 2.2E-8 T 06-07-2017 CAK77_RS04285 e510a3900d1dad44365bb934cb4a0ce1 363 SUPERFAMILY SSF89796 8 352 3.27E-105 T 06-07-2017 IPR023606 CoA-transferase family III domain CAK77_RS00645 97e17b2fe5f1be9603b7a6cb3b61893b 336 Pfam PF14716 Helix-hairpin-helix domain 4 68 4.2E-11 T 06-07-2017 IPR010996 DNA polymerase beta-like, N-terminal domain CAK77_RS00645 97e17b2fe5f1be9603b7a6cb3b61893b 336 Pfam PF02811 PHP domain 99 194 5.4E-9 T 06-07-2017 IPR004013 PHP domain GO:0003824 CAK77_RS00645 97e17b2fe5f1be9603b7a6cb3b61893b 336 PIRSF PIRSF036978 1 336 3.4E-178 T 06-07-2017 IPR017078 Uncharacterised conserved protein UCP036978, histidinol phosphatase-related hydrolase, SCO0789 CAK77_RS00645 97e17b2fe5f1be9603b7a6cb3b61893b 336 Gene3D G3DSA:1.10.150.110 4 81 1.7E-8 T 06-07-2017 IPR027421 DNA polymerase family X lyase domain CAK77_RS00645 97e17b2fe5f1be9603b7a6cb3b61893b 336 Gene3D G3DSA:3.20.20.140 97 333 4.3E-49 T 06-07-2017 CAK77_RS00645 97e17b2fe5f1be9603b7a6cb3b61893b 336 SMART SM00481 98 177 3.4E-21 T 06-07-2017 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 CAK77_RS00645 97e17b2fe5f1be9603b7a6cb3b61893b 336 SUPERFAMILY SSF89550 97 332 1.44E-50 T 06-07-2017 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CAK77_RS00645 97e17b2fe5f1be9603b7a6cb3b61893b 336 SUPERFAMILY SSF47802 3 82 1.7E-12 T 06-07-2017 IPR010996 DNA polymerase beta-like, N-terminal domain CAK77_RS18935 66cfc62e9fb983f5ba6fd58a13d96486 221 Gene3D G3DSA:3.30.230.10 112 192 1.1E-31 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CAK77_RS18935 66cfc62e9fb983f5ba6fd58a13d96486 221 SUPERFAMILY SSF54768 42 110 4.29E-22 T 06-07-2017 CAK77_RS18935 66cfc62e9fb983f5ba6fd58a13d96486 221 ProSitePatterns PS00585 Ribosomal protein S5 signature. 62 94 - T 06-07-2017 IPR018192 Ribosomal protein S5, N-terminal, conserved site CAK77_RS18935 66cfc62e9fb983f5ba6fd58a13d96486 221 Pfam PF00333 Ribosomal protein S5, N-terminal domain 47 109 2.6E-27 T 06-07-2017 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 CAK77_RS18935 66cfc62e9fb983f5ba6fd58a13d96486 221 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 43 197 9.5E-69 T 06-07-2017 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 CAK77_RS18935 66cfc62e9fb983f5ba6fd58a13d96486 221 Gene3D G3DSA:3.30.160.20 44 106 8.0E-29 T 06-07-2017 IPR014720 Double-stranded RNA-binding domain CAK77_RS18935 66cfc62e9fb983f5ba6fd58a13d96486 221 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 2 197 34.516 T 06-07-2017 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 CAK77_RS18935 66cfc62e9fb983f5ba6fd58a13d96486 221 Pfam PF03719 Ribosomal protein S5, C-terminal domain 121 191 2.5E-28 T 06-07-2017 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 CAK77_RS18935 66cfc62e9fb983f5ba6fd58a13d96486 221 SUPERFAMILY SSF54211 113 192 1.64E-24 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAK77_RS21225 95ab4d1ebfc5d81968ef0ccbfc03a2ed 162 Pfam PF00583 Acetyltransferase (GNAT) family 76 141 8.1E-10 T 06-07-2017 IPR000182 GNAT domain GO:0008080 CAK77_RS21225 95ab4d1ebfc5d81968ef0ccbfc03a2ed 162 Gene3D G3DSA:3.40.630.30 46 144 6.9E-19 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS21225 95ab4d1ebfc5d81968ef0ccbfc03a2ed 162 SUPERFAMILY SSF55729 10 147 2.27E-18 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS04360 c1c0bb950f8ac9e907ec1ac78e3ecd5e 550 SMART SM00487 178 353 1.5E-22 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain CAK77_RS04360 c1c0bb950f8ac9e907ec1ac78e3ecd5e 550 Pfam PF04851 Type III restriction enzyme, res subunit 181 327 1.0E-13 T 06-07-2017 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CAK77_RS04360 c1c0bb950f8ac9e907ec1ac78e3ecd5e 550 Pfam PF16203 ERCC3/RAD25/XPB C-terminal helicase 353 539 1.8E-44 T 06-07-2017 IPR032438 ERCC3/RAD25/XPB helicase, C-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 CAK77_RS04360 c1c0bb950f8ac9e907ec1ac78e3ecd5e 550 SUPERFAMILY SSF52540 145 345 7.7E-32 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS04360 c1c0bb950f8ac9e907ec1ac78e3ecd5e 550 Pfam PF13625 Helicase conserved C-terminal domain 6 134 9.6E-46 T 06-07-2017 IPR032830 Helicase XPB/Ssl2, N-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 CAK77_RS04360 c1c0bb950f8ac9e907ec1ac78e3ecd5e 550 Gene3D G3DSA:3.40.50.300 386 530 2.2E-11 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS04360 c1c0bb950f8ac9e907ec1ac78e3ecd5e 550 SMART SM00490 420 500 8.5E-10 T 06-07-2017 IPR001650 Helicase, C-terminal CAK77_RS04360 c1c0bb950f8ac9e907ec1ac78e3ecd5e 550 SUPERFAMILY SSF52540 393 511 3.43E-26 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS04360 c1c0bb950f8ac9e907ec1ac78e3ecd5e 550 SUPERFAMILY SSF52540 290 360 3.43E-26 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS04360 c1c0bb950f8ac9e907ec1ac78e3ecd5e 550 Gene3D G3DSA:3.40.50.300 180 344 4.2E-28 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS04360 c1c0bb950f8ac9e907ec1ac78e3ecd5e 550 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 356 378 4.7E-34 T 06-07-2017 CAK77_RS04360 c1c0bb950f8ac9e907ec1ac78e3ecd5e 550 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 291 311 4.7E-34 T 06-07-2017 CAK77_RS04360 c1c0bb950f8ac9e907ec1ac78e3ecd5e 550 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 191 213 4.7E-34 T 06-07-2017 CAK77_RS04360 c1c0bb950f8ac9e907ec1ac78e3ecd5e 550 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 456 474 4.7E-34 T 06-07-2017 CAK77_RS04360 c1c0bb950f8ac9e907ec1ac78e3ecd5e 550 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 475 500 4.7E-34 T 06-07-2017 CAK77_RS14195 8eff896ec5a99dcda8693c93e655920e 209 Gene3D G3DSA:3.10.129.10 59 207 2.8E-32 T 06-07-2017 IPR029069 HotDog domain CAK77_RS14195 8eff896ec5a99dcda8693c93e655920e 209 Pfam PF03061 Thioesterase superfamily 119 195 1.5E-5 T 06-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 CAK77_RS14195 8eff896ec5a99dcda8693c93e655920e 209 SUPERFAMILY SSF54637 15 202 1.26E-42 T 06-07-2017 IPR029069 HotDog domain CAK77_RS16125 167d22e4839de04322a204da0108c5f3 457 SUPERFAMILY SSF47364 156 235 3.4E-15 T 06-07-2017 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CAK77_RS16125 167d22e4839de04322a204da0108c5f3 457 Gene3D G3DSA:1.20.120.140 164 243 1.8E-16 T 06-07-2017 CAK77_RS16125 167d22e4839de04322a204da0108c5f3 457 SUPERFAMILY SSF52540 252 456 8.76E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS16125 167d22e4839de04322a204da0108c5f3 457 SMART SM00963 161 241 8.9E-14 T 06-07-2017 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CAK77_RS16125 167d22e4839de04322a204da0108c5f3 457 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 430 443 - T 06-07-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CAK77_RS16125 167d22e4839de04322a204da0108c5f3 457 SMART SM00962 258 457 5.4E-97 T 06-07-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CAK77_RS16125 167d22e4839de04322a204da0108c5f3 457 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 185 456 2.4E-105 T 06-07-2017 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 CAK77_RS16125 167d22e4839de04322a204da0108c5f3 457 Pfam PF02881 SRP54-type protein, helical bundle domain 178 236 3.9E-8 T 06-07-2017 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CAK77_RS16125 167d22e4839de04322a204da0108c5f3 457 SMART SM00382 257 402 4.0E-8 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS16125 167d22e4839de04322a204da0108c5f3 457 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 184 457 57.737 T 06-07-2017 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 CAK77_RS16125 167d22e4839de04322a204da0108c5f3 457 Gene3D G3DSA:3.40.50.300 252 457 1.7E-70 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS16125 167d22e4839de04322a204da0108c5f3 457 Pfam PF00448 SRP54-type protein, GTPase domain 258 457 8.5E-71 T 06-07-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CAK77_RS23570 98b4dae0ddf09882d09f5558da296a64 307 Pfam PF04542 Sigma-70 region 2 7 71 5.8E-14 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS23570 98b4dae0ddf09882d09f5558da296a64 307 Pfam PF08281 Sigma-70, region 4 102 153 9.9E-10 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS23570 98b4dae0ddf09882d09f5558da296a64 307 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 7 153 8.5E-15 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS23570 98b4dae0ddf09882d09f5558da296a64 307 SUPERFAMILY SSF88946 5 67 7.06E-13 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS23570 98b4dae0ddf09882d09f5558da296a64 307 Gene3D G3DSA:3.10.450.50 157 229 1.1E-4 T 06-07-2017 IPR032710 NTF2-like domain CAK77_RS23570 98b4dae0ddf09882d09f5558da296a64 307 Gene3D G3DSA:1.10.10.10 96 153 1.0E-8 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS23570 98b4dae0ddf09882d09f5558da296a64 307 SUPERFAMILY SSF54427 167 231 3.36E-7 T 06-07-2017 IPR032710 NTF2-like domain CAK77_RS23570 98b4dae0ddf09882d09f5558da296a64 307 Gene3D G3DSA:1.10.1740.10 7 72 5.1E-14 T 06-07-2017 CAK77_RS23570 98b4dae0ddf09882d09f5558da296a64 307 SUPERFAMILY SSF88659 94 153 2.8E-8 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS20755 c6a1d3c9bc5ed4e74acc096874ac0e72 526 SUPERFAMILY SSF53474 110 267 5.85E-5 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS20755 c6a1d3c9bc5ed4e74acc096874ac0e72 526 SUPERFAMILY SSF53474 86 163 5.23E-6 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS20755 c6a1d3c9bc5ed4e74acc096874ac0e72 526 Pfam PF08237 PE-PPE domain 74 296 6.0E-55 T 06-07-2017 IPR013228 PE-PPE, C-terminal CAK77_RS20755 c6a1d3c9bc5ed4e74acc096874ac0e72 526 Gene3D G3DSA:3.40.50.1820 63 140 1.1E-4 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS05905 8b71eaac3d4f6d4ce47684280845a536 129 Gene3D G3DSA:3.10.180.10 9 124 2.9E-26 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK77_RS05905 8b71eaac3d4f6d4ce47684280845a536 129 SUPERFAMILY SSF54593 11 124 1.79E-20 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK77_RS05905 8b71eaac3d4f6d4ce47684280845a536 129 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 12 122 1.5E-13 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CAK77_RS20525 55fd0d3be563151cf6036fdf60edf1b9 267 Pfam PF11139 Sap, sulfolipid-1-addressing protein 5 264 3.3E-72 T 06-07-2017 IPR021315 Glycolipid exporter Gap/Sap CAK77_RS13005 5f01995da9898de4658434458de0c0af 262 Pfam PF00290 Tryptophan synthase alpha chain 11 243 2.8E-68 T 06-07-2017 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CAK77_RS13005 5f01995da9898de4658434458de0c0af 262 Gene3D G3DSA:3.20.20.70 6 260 2.4E-90 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK77_RS13005 5f01995da9898de4658434458de0c0af 262 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 11 240 2.5E-63 T 06-07-2017 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CAK77_RS13005 5f01995da9898de4658434458de0c0af 262 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 17 258 31.548 T 06-07-2017 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CAK77_RS13005 5f01995da9898de4658434458de0c0af 262 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 51 64 - T 06-07-2017 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CAK77_RS13005 5f01995da9898de4658434458de0c0af 262 SUPERFAMILY SSF51366 6 249 6.04E-78 T 06-07-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CAK77_RS01225 3057d450962bc03898653c83a136009f 173 SUPERFAMILY SSF82784 14 167 3.8E-43 T 06-07-2017 IPR003718 OsmC/Ohr family CAK77_RS01225 3057d450962bc03898653c83a136009f 173 Pfam PF02566 OsmC-like protein 61 165 2.7E-22 T 06-07-2017 IPR003718 OsmC/Ohr family CAK77_RS01225 3057d450962bc03898653c83a136009f 173 Gene3D G3DSA:3.30.300.20 12 155 1.9E-45 T 06-07-2017 IPR015946 K homology domain-like, alpha/beta CAK77_RS09550 1890c39430387c26611ebfa362378182 145 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 11 138 1.0E-31 T 06-07-2017 IPR019920 F420-binding domain, putative CAK77_RS09550 1890c39430387c26611ebfa362378182 145 Gene3D G3DSA:2.30.110.10 2 139 2.4E-25 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS09550 1890c39430387c26611ebfa362378182 145 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 13 94 2.4E-12 T 06-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAK77_RS09550 1890c39430387c26611ebfa362378182 145 SUPERFAMILY SSF50475 1 133 2.06E-25 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS08250 630922fbcffeeae9f80400df814ef7a2 288 Hamap MF_01987 Ribokinase [rbsK]. 5 284 21.47 T 06-07-2017 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15 CAK77_RS08250 630922fbcffeeae9f80400df814ef7a2 288 SUPERFAMILY SSF53613 6 279 8.42E-61 T 06-07-2017 IPR029056 Ribokinase-like CAK77_RS08250 630922fbcffeeae9f80400df814ef7a2 288 Pfam PF00294 pfkB family carbohydrate kinase 6 277 5.6E-46 T 06-07-2017 IPR011611 Carbohydrate kinase PfkB CAK77_RS08250 630922fbcffeeae9f80400df814ef7a2 288 PRINTS PR00990 Ribokinase signature 177 192 2.3E-29 T 06-07-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 CAK77_RS08250 630922fbcffeeae9f80400df814ef7a2 288 PRINTS PR00990 Ribokinase signature 202 213 2.3E-29 T 06-07-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 CAK77_RS08250 630922fbcffeeae9f80400df814ef7a2 288 PRINTS PR00990 Ribokinase signature 9 30 2.3E-29 T 06-07-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 CAK77_RS08250 630922fbcffeeae9f80400df814ef7a2 288 PRINTS PR00990 Ribokinase signature 36 55 2.3E-29 T 06-07-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 CAK77_RS08250 630922fbcffeeae9f80400df814ef7a2 288 PRINTS PR00990 Ribokinase signature 107 120 2.3E-29 T 06-07-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 CAK77_RS08250 630922fbcffeeae9f80400df814ef7a2 288 Gene3D G3DSA:3.40.1190.20 6 282 9.3E-77 T 06-07-2017 IPR029056 Ribokinase-like CAK77_RS01600 8bafa66bc8cdec88888a3b000e6e068a 194 SUPERFAMILY SSF46689 1 71 9.23E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS01600 8bafa66bc8cdec88888a3b000e6e068a 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 1 44 5.9E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS01600 8bafa66bc8cdec88888a3b000e6e068a 194 SUPERFAMILY SSF48498 65 185 1.44E-32 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS01600 8bafa66bc8cdec88888a3b000e6e068a 194 Gene3D G3DSA:1.10.357.10 46 184 1.1E-23 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS01600 8bafa66bc8cdec88888a3b000e6e068a 194 Gene3D G3DSA:1.10.10.60 1 45 4.1E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS15135 050e8674398921b7df1b9dfcbae7829c 384 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 236 384 4.5E-45 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS15135 050e8674398921b7df1b9dfcbae7829c 384 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 343 362 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CAK77_RS15135 050e8674398921b7df1b9dfcbae7829c 384 Gene3D G3DSA:2.40.110.10 129 229 2.0E-40 T 06-07-2017 CAK77_RS15135 050e8674398921b7df1b9dfcbae7829c 384 SUPERFAMILY SSF56645 10 248 1.96E-78 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK77_RS15135 050e8674398921b7df1b9dfcbae7829c 384 Gene3D G3DSA:1.20.140.10 230 384 1.1E-56 T 06-07-2017 CAK77_RS15135 050e8674398921b7df1b9dfcbae7829c 384 Gene3D G3DSA:1.10.540.10 12 127 5.6E-27 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS15135 050e8674398921b7df1b9dfcbae7829c 384 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 129 224 3.5E-24 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAK77_RS15135 050e8674398921b7df1b9dfcbae7829c 384 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 14 125 7.7E-26 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS15135 050e8674398921b7df1b9dfcbae7829c 384 SUPERFAMILY SSF47203 234 384 8.54E-47 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS20125 ca8afe4ed1d8a0b9dbb8b6c8d661e439 518 SUPERFAMILY SSF51905 240 446 3.94E-14 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS20125 ca8afe4ed1d8a0b9dbb8b6c8d661e439 518 Gene3D G3DSA:3.50.50.60 7 180 6.0E-53 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS20125 ca8afe4ed1d8a0b9dbb8b6c8d661e439 518 Gene3D G3DSA:3.50.50.60 394 484 6.0E-53 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS20125 ca8afe4ed1d8a0b9dbb8b6c8d661e439 518 Gene3D G3DSA:3.50.50.60 181 224 8.9E-6 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS20125 ca8afe4ed1d8a0b9dbb8b6c8d661e439 518 Gene3D G3DSA:3.50.50.60 310 350 8.9E-6 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS20125 ca8afe4ed1d8a0b9dbb8b6c8d661e439 518 SUPERFAMILY SSF51905 6 230 1.08E-45 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS20125 ca8afe4ed1d8a0b9dbb8b6c8d661e439 518 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 13 216 3.0E-11 T 06-07-2017 CAK77_RS20125 ca8afe4ed1d8a0b9dbb8b6c8d661e439 518 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 10 32 6.5E-5 T 06-07-2017 CAK77_RS20125 ca8afe4ed1d8a0b9dbb8b6c8d661e439 518 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 177 202 6.5E-5 T 06-07-2017 CAK77_RS04195 ba5e6dc151a5761c3e86bf115822a445 370 SUPERFAMILY SSF89796 3 368 2.35E-118 T 06-07-2017 IPR023606 CoA-transferase family III domain CAK77_RS04195 ba5e6dc151a5761c3e86bf115822a445 370 Pfam PF02515 CoA-transferase family III 5 367 1.2E-120 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 CAK77_RS04195 ba5e6dc151a5761c3e86bf115822a445 370 Gene3D G3DSA:3.30.1540.10 222 304 1.1E-31 T 06-07-2017 CAK77_RS04195 ba5e6dc151a5761c3e86bf115822a445 370 Gene3D G3DSA:3.40.50.10540 4 216 4.6E-93 T 06-07-2017 IPR023606 CoA-transferase family III domain CAK77_RS04195 ba5e6dc151a5761c3e86bf115822a445 370 Gene3D G3DSA:3.40.50.10540 305 369 4.6E-93 T 06-07-2017 IPR023606 CoA-transferase family III domain CAK77_RS14415 472e393b2ea86905dc147f251bd0717d 539 SUPERFAMILY SSF142984 371 451 2.35E-15 T 06-07-2017 CAK77_RS14415 472e393b2ea86905dc147f251bd0717d 539 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 460 526 2.4E-10 T 06-07-2017 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS14415 472e393b2ea86905dc147f251bd0717d 539 SMART SM00928 457 504 0.0077 T 06-07-2017 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS14415 472e393b2ea86905dc147f251bd0717d 539 SUPERFAMILY SSF140490 454 528 2.62E-11 T 06-07-2017 CAK77_RS14415 472e393b2ea86905dc147f251bd0717d 539 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 178 348 7.6E-48 T 06-07-2017 IPR011538 NADH-ubiquinone oxidoreductase 51 kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS14415 472e393b2ea86905dc147f251bd0717d 539 SUPERFAMILY SSF142019 147 369 2.88E-75 T 06-07-2017 CAK77_RS14415 472e393b2ea86905dc147f251bd0717d 539 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 470 481 - T 06-07-2017 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS20305 dabff0c7fec5ae7c558a871ab48c930a 294 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 168 187 5.8E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS20305 dabff0c7fec5ae7c558a871ab48c930a 294 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 156 5.8E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS20305 dabff0c7fec5ae7c558a871ab48c930a 294 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 94 105 5.8E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS20305 dabff0c7fec5ae7c558a871ab48c930a 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 189 206 1.2E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS20305 dabff0c7fec5ae7c558a871ab48c930a 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 142 158 1.2E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS20305 dabff0c7fec5ae7c558a871ab48c930a 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 21 38 1.2E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS20305 dabff0c7fec5ae7c558a871ab48c930a 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 94 105 1.2E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS20305 dabff0c7fec5ae7c558a871ab48c930a 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 187 1.2E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS20305 dabff0c7fec5ae7c558a871ab48c930a 294 SUPERFAMILY SSF51735 20 272 3.55E-60 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS20305 dabff0c7fec5ae7c558a871ab48c930a 294 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 155 183 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK77_RS20305 dabff0c7fec5ae7c558a871ab48c930a 294 Gene3D G3DSA:3.40.50.720 20 267 1.1E-59 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS20305 dabff0c7fec5ae7c558a871ab48c930a 294 Pfam PF00106 short chain dehydrogenase 22 207 1.4E-44 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS16455 3e6ba6245b39a6546d7474e52a2f1eb5 337 SUPERFAMILY SSF53659 2 336 1.58E-108 T 06-07-2017 CAK77_RS16455 3e6ba6245b39a6546d7474e52a2f1eb5 337 SMART SM01329 3 333 2.0E-160 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CAK77_RS16455 3e6ba6245b39a6546d7474e52a2f1eb5 337 Gene3D G3DSA:3.40.718.10 3 326 2.3E-111 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CAK77_RS16455 3e6ba6245b39a6546d7474e52a2f1eb5 337 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 3 318 1.3E-83 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CAK77_RS16455 3e6ba6245b39a6546d7474e52a2f1eb5 337 Hamap MF_01035 3-isopropylmalate dehydrogenase [leuB]. 2 337 57.875 T 06-07-2017 IPR023698 3-isopropylmalate dehydrogenase GO:0003862|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 CAK77_RS16455 3e6ba6245b39a6546d7474e52a2f1eb5 337 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 232 251 - T 06-07-2017 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 CAK77_RS09450 1f291b8d877f7cd4cc373c2b4a3172e5 76 SUPERFAMILY SSF69786 5 75 2.75E-17 T 06-07-2017 IPR003746 Protein of unknown function DUF167 CAK77_RS09450 1f291b8d877f7cd4cc373c2b4a3172e5 76 Pfam PF02594 Uncharacterised ACR, YggU family COG1872 8 75 1.3E-17 T 06-07-2017 IPR003746 Protein of unknown function DUF167 CAK77_RS09450 1f291b8d877f7cd4cc373c2b4a3172e5 76 SMART SM01152 1 76 3.3E-19 T 06-07-2017 IPR003746 Protein of unknown function DUF167 CAK77_RS09450 1f291b8d877f7cd4cc373c2b4a3172e5 76 Gene3D G3DSA:3.30.1200.10 7 75 9.6E-17 T 06-07-2017 IPR003746 Protein of unknown function DUF167 CAK77_RS21095 0ac0adb5df8ba9d3dde8b57be511e2d6 316 Gene3D G3DSA:3.60.130.10 13 292 8.2E-76 T 06-07-2017 CAK77_RS21095 0ac0adb5df8ba9d3dde8b57be511e2d6 316 SUPERFAMILY SSF51197 14 292 1.1E-73 T 06-07-2017 CAK77_RS21095 0ac0adb5df8ba9d3dde8b57be511e2d6 316 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 17 278 4.9E-43 T 06-07-2017 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 CAK77_RS03560 d63bc9e00267435f2d7d3eab8c07da4e 472 Pfam PF10397 Adenylosuccinate lyase C-terminus 366 449 1.8E-14 T 06-07-2017 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CAK77_RS03560 d63bc9e00267435f2d7d3eab8c07da4e 472 SUPERFAMILY SSF48557 6 451 7.54E-84 T 06-07-2017 IPR008948 L-Aspartase-like GO:0003824 CAK77_RS03560 d63bc9e00267435f2d7d3eab8c07da4e 472 PRINTS PR00149 Fumarate lyase superfamily signature 94 112 4.2E-10 T 06-07-2017 IPR000362 Fumarate lyase family CAK77_RS03560 d63bc9e00267435f2d7d3eab8c07da4e 472 PRINTS PR00149 Fumarate lyase superfamily signature 276 292 4.2E-10 T 06-07-2017 IPR000362 Fumarate lyase family CAK77_RS03560 d63bc9e00267435f2d7d3eab8c07da4e 472 PRINTS PR00149 Fumarate lyase superfamily signature 139 157 4.2E-10 T 06-07-2017 IPR000362 Fumarate lyase family CAK77_RS03560 d63bc9e00267435f2d7d3eab8c07da4e 472 SMART SM00998 365 450 3.5E-22 T 06-07-2017 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CAK77_RS03560 d63bc9e00267435f2d7d3eab8c07da4e 472 Pfam PF00206 Lyase 39 295 6.8E-23 T 06-07-2017 IPR022761 Fumarate lyase, N-terminal CAK77_RS03560 d63bc9e00267435f2d7d3eab8c07da4e 472 Gene3D G3DSA:1.20.200.10 98 448 8.4E-81 T 06-07-2017 CAK77_RS03560 d63bc9e00267435f2d7d3eab8c07da4e 472 ProSitePatterns PS00163 Fumarate lyases signature. 276 285 - T 06-07-2017 IPR020557 Fumarate lyase, conserved site GO:0003824 CAK77_RS03560 d63bc9e00267435f2d7d3eab8c07da4e 472 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 7 450 8.1E-136 T 06-07-2017 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CAK77_RS03560 d63bc9e00267435f2d7d3eab8c07da4e 472 Gene3D G3DSA:1.10.275.10 9 97 1.4E-22 T 06-07-2017 IPR024083 Fumarase/histidase, N-terminal CAK77_RS11045 6b71d973280da6b245209a6af1ce3148 237 Pfam PF07729 FCD domain 92 218 5.2E-18 T 06-07-2017 IPR011711 GntR, C-terminal CAK77_RS11045 6b71d973280da6b245209a6af1ce3148 237 SMART SM00345 13 72 5.0E-19 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK77_RS11045 6b71d973280da6b245209a6af1ce3148 237 SMART SM00895 92 219 1.2E-16 T 06-07-2017 IPR011711 GntR, C-terminal CAK77_RS11045 6b71d973280da6b245209a6af1ce3148 237 SUPERFAMILY SSF46785 2 76 4.67E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS11045 6b71d973280da6b245209a6af1ce3148 237 Gene3D G3DSA:1.10.10.10 5 74 4.7E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS11045 6b71d973280da6b245209a6af1ce3148 237 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 72 8.2E-20 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK77_RS11045 6b71d973280da6b245209a6af1ce3148 237 Gene3D G3DSA:1.20.120.530 91 223 1.4E-18 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAK77_RS11045 6b71d973280da6b245209a6af1ce3148 237 SUPERFAMILY SSF48008 91 218 6.54E-18 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAK77_RS11045 6b71d973280da6b245209a6af1ce3148 237 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 32 46 6.0E-7 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK77_RS11045 6b71d973280da6b245209a6af1ce3148 237 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 46 62 6.0E-7 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK77_RS21310 8eb5ce056d36b3a043dabcba6fb4438d 221 SUPERFAMILY SSF55136 21 207 3.19E-46 T 06-07-2017 IPR011256 Regulatory factor, effector binding domain CAK77_RS21310 8eb5ce056d36b3a043dabcba6fb4438d 221 Pfam PF04832 SOUL heme-binding protein 29 206 2.6E-40 T 06-07-2017 IPR006917 SOUL haem-binding protein CAK77_RS13435 cd2eeebbc891507747fe047fdfe6ce38 164 SUPERFAMILY SSF55729 1 162 1.8E-28 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS13435 cd2eeebbc891507747fe047fdfe6ce38 164 PIRSF PIRSF037663 1 164 1.0E-57 T 06-07-2017 IPR017255 Acetyltransferase, GNAT, predicted CAK77_RS13435 cd2eeebbc891507747fe047fdfe6ce38 164 Pfam PF00583 Acetyltransferase (GNAT) family 53 131 3.8E-15 T 06-07-2017 IPR000182 GNAT domain GO:0008080 CAK77_RS13435 cd2eeebbc891507747fe047fdfe6ce38 164 Gene3D G3DSA:3.40.630.30 1 161 1.9E-34 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS03415 fbc26e5273ba61152b42715d29f1a8bc 289 SUPERFAMILY SSF51197 8 280 7.78E-55 T 06-07-2017 CAK77_RS03415 fbc26e5273ba61152b42715d29f1a8bc 289 Gene3D G3DSA:3.60.130.10 9 280 1.1E-50 T 06-07-2017 CAK77_RS03415 fbc26e5273ba61152b42715d29f1a8bc 289 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 10 263 6.1E-33 T 06-07-2017 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 CAK77_RS12130 0efd6fbec4f5707cb90a2e0b63b74870 409 Gene3D G3DSA:1.10.540.10 1 124 1.2E-22 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS12130 0efd6fbec4f5707cb90a2e0b63b74870 409 Gene3D G3DSA:2.40.110.10 127 223 8.8E-31 T 06-07-2017 CAK77_RS12130 0efd6fbec4f5707cb90a2e0b63b74870 409 Gene3D G3DSA:1.20.140.10 224 408 1.5E-22 T 06-07-2017 CAK77_RS12130 0efd6fbec4f5707cb90a2e0b63b74870 409 SUPERFAMILY SSF47203 378 409 8.38E-19 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS12130 0efd6fbec4f5707cb90a2e0b63b74870 409 SUPERFAMILY SSF47203 234 350 8.38E-19 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS12130 0efd6fbec4f5707cb90a2e0b63b74870 409 SUPERFAMILY SSF56645 2 244 3.27E-66 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK77_RS12130 0efd6fbec4f5707cb90a2e0b63b74870 409 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 233 405 1.1E-17 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS12130 0efd6fbec4f5707cb90a2e0b63b74870 409 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 123 2.2E-17 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS12130 0efd6fbec4f5707cb90a2e0b63b74870 409 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 127 205 4.1E-16 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAK77_RS13160 b7653fa47a40ded7f06231b13d120905 342 Gene3D G3DSA:3.20.20.70 29 334 4.3E-79 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK77_RS13160 b7653fa47a40ded7f06231b13d120905 342 SUPERFAMILY SSF102114 28 325 1.18E-66 T 06-07-2017 CAK77_RS13160 b7653fa47a40ded7f06231b13d120905 342 PIRSF PIRSF001619 11 341 2.5E-106 T 06-07-2017 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CAK77_RS13160 b7653fa47a40ded7f06231b13d120905 342 Pfam PF04055 Radical SAM superfamily 75 231 6.7E-15 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 CAK77_RS13160 b7653fa47a40ded7f06231b13d120905 342 TIGRFAM TIGR00433 bioB: biotin synthase 40 333 1.1E-107 T 06-07-2017 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CAK77_RS13160 b7653fa47a40ded7f06231b13d120905 342 SMART SM00876 243 335 1.6E-28 T 06-07-2017 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CAK77_RS13160 b7653fa47a40ded7f06231b13d120905 342 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 243 331 1.1E-11 T 06-07-2017 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CAK77_RS13160 b7653fa47a40ded7f06231b13d120905 342 SMART SM00729 68 275 6.0E-36 T 06-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CAK77_RS13160 b7653fa47a40ded7f06231b13d120905 342 Hamap MF_01694 Biotin synthase [bioB]. 28 336 38.315 T 06-07-2017 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CAK77_RS14620 fcb875387c56af3fee6fd97af6615847 180 Gene3D G3DSA:1.10.3330.10 15 165 2.5E-42 T 06-07-2017 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394 CAK77_RS14620 fcb875387c56af3fee6fd97af6615847 180 TIGRFAM TIGR03180 UraD_2: OHCU decarboxylase 12 163 6.5E-50 T 06-07-2017 IPR017595 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase, type 2 CAK77_RS14620 fcb875387c56af3fee6fd97af6615847 180 Pfam PF09349 OHCU decarboxylase 13 161 3.4E-39 T 06-07-2017 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394 CAK77_RS14620 fcb875387c56af3fee6fd97af6615847 180 SUPERFAMILY SSF158694 9 164 8.89E-43 T 06-07-2017 CAK77_RS19410 da5393287e5b433f609a4aa539b110ab 408 Pfam PF04542 Sigma-70 region 2 12 73 1.1E-10 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS19410 da5393287e5b433f609a4aa539b110ab 408 Pfam PF08281 Sigma-70, region 4 106 158 6.6E-7 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS19410 da5393287e5b433f609a4aa539b110ab 408 SUPERFAMILY SSF88946 8 86 1.22E-11 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS19410 da5393287e5b433f609a4aa539b110ab 408 Gene3D G3DSA:1.10.1740.10 5 73 2.3E-9 T 06-07-2017 CAK77_RS19410 da5393287e5b433f609a4aa539b110ab 408 SUPERFAMILY SSF88659 99 160 4.11E-10 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS19410 da5393287e5b433f609a4aa539b110ab 408 Gene3D G3DSA:1.10.10.10 100 160 1.2E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS19410 da5393287e5b433f609a4aa539b110ab 408 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 17 160 5.7E-13 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS19410 da5393287e5b433f609a4aa539b110ab 408 Gene3D G3DSA:1.25.40.10 319 391 3.6E-5 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK77_RS19410 da5393287e5b433f609a4aa539b110ab 408 SUPERFAMILY SSF48452 318 404 1.08E-5 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK77_RS21035 075426cbe030b57d3bc2b7a7e228c827 278 Pfam PF08543 Phosphomethylpyrimidine kinase 25 270 2.1E-86 T 06-07-2017 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-964975 CAK77_RS21035 075426cbe030b57d3bc2b7a7e228c827 278 SUPERFAMILY SSF53613 17 274 9.51E-77 T 06-07-2017 IPR029056 Ribokinase-like CAK77_RS21035 075426cbe030b57d3bc2b7a7e228c827 278 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 18 271 3.4E-85 T 06-07-2017 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CAK77_RS21035 075426cbe030b57d3bc2b7a7e228c827 278 Gene3D G3DSA:3.40.1190.20 17 271 9.9E-93 T 06-07-2017 IPR029056 Ribokinase-like CAK77_RS21645 b6b46bfd8c07f6b205742bcd1898ec3b 475 ProDom PD092006 MEMBRANE YWOB TRANSMEMBRANE 168 280 2.0E-12 T 06-07-2017 IPR020218 Uncharacterised protein family, YwoB, transmembrane CAK77_RS07585 a66efc17430dfd261147f401ff37afc9 250 ProSitePatterns PS01081 TetR-type HTH domain signature. 49 80 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CAK77_RS07585 a66efc17430dfd261147f401ff37afc9 250 SUPERFAMILY SSF48498 102 242 4.34E-18 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS07585 a66efc17430dfd261147f401ff37afc9 250 Pfam PF00440 Bacterial regulatory proteins, tetR family 37 83 3.2E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS07585 a66efc17430dfd261147f401ff37afc9 250 Gene3D G3DSA:1.10.357.10 23 243 2.4E-42 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS07585 a66efc17430dfd261147f401ff37afc9 250 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 99 234 2.2E-7 T 06-07-2017 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 CAK77_RS07585 a66efc17430dfd261147f401ff37afc9 250 SUPERFAMILY SSF46689 26 91 1.55E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS24020 f74b732e71714075534c65d21945c265 54 Gene3D G3DSA:3.20.20.100 1 54 7.4E-10 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAK77_RS24020 f74b732e71714075534c65d21945c265 54 SUPERFAMILY SSF51430 1 54 6.68E-11 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAK77_RS19185 76de3378a9d2e1d40376e06dafe47194 273 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 171 190 2.4E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS19185 76de3378a9d2e1d40376e06dafe47194 273 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 97 108 2.4E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS19185 76de3378a9d2e1d40376e06dafe47194 273 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 159 2.4E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS19185 76de3378a9d2e1d40376e06dafe47194 273 TIGRFAM TIGR03971 SDR_subfam_1: SDR family mycofactocin-dependent oxidoreductase 6 271 1.6E-112 T 06-07-2017 IPR023985 Mycofactocin-dependent oxidoreductase CAK77_RS19185 76de3378a9d2e1d40376e06dafe47194 273 Gene3D G3DSA:3.40.50.720 3 270 7.6E-78 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS19185 76de3378a9d2e1d40376e06dafe47194 273 SUPERFAMILY SSF51735 5 272 8.86E-72 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS19185 76de3378a9d2e1d40376e06dafe47194 273 Pfam PF00106 short chain dehydrogenase 9 210 5.3E-50 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS19185 76de3378a9d2e1d40376e06dafe47194 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 97 108 3.3E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS19185 76de3378a9d2e1d40376e06dafe47194 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 234 254 3.3E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS19185 76de3378a9d2e1d40376e06dafe47194 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 161 3.3E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS19185 76de3378a9d2e1d40376e06dafe47194 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 190 3.3E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS19185 76de3378a9d2e1d40376e06dafe47194 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 3.3E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS19185 76de3378a9d2e1d40376e06dafe47194 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 192 209 3.3E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS17730 3a44789b8cf76f54517366b60e9b1e3f 496 Gene3D G3DSA:3.30.565.10 351 489 3.9E-18 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS17730 3a44789b8cf76f54517366b60e9b1e3f 496 SUPERFAMILY SSF55785 176 287 1.0E-4 T 06-07-2017 IPR000014 PAS domain CAK77_RS17730 3a44789b8cf76f54517366b60e9b1e3f 496 Pfam PF07568 Histidine kinase 296 363 1.3E-22 T 06-07-2017 IPR011495 Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain CAK77_RS17730 3a44789b8cf76f54517366b60e9b1e3f 496 SUPERFAMILY SSF55874 355 488 8.25E-18 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS17730 3a44789b8cf76f54517366b60e9b1e3f 496 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 394 488 4.5E-9 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS17730 3a44789b8cf76f54517366b60e9b1e3f 496 Gene3D G3DSA:3.30.450.20 174 279 1.4E-5 T 06-07-2017 CAK77_RS17730 3a44789b8cf76f54517366b60e9b1e3f 496 SMART SM00387 390 490 7.9E-9 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS17730 3a44789b8cf76f54517366b60e9b1e3f 496 Pfam PF12282 Signal transduction histidine kinase 4 147 2.0E-48 T 06-07-2017 IPR022066 Signal transduction histidine kinase CAK77_RS23820 9e32138197df54b7deec89d28f2162eb 552 ProSitePatterns PS00211 ABC transporters family signature. 166 180 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK77_RS23820 9e32138197df54b7deec89d28f2162eb 552 Pfam PF00005 ABC transporter 22 194 1.2E-22 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK77_RS23820 9e32138197df54b7deec89d28f2162eb 552 Pfam PF00005 ABC transporter 374 502 3.7E-21 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK77_RS23820 9e32138197df54b7deec89d28f2162eb 552 SUPERFAMILY SSF52540 342 551 4.87E-41 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS23820 9e32138197df54b7deec89d28f2162eb 552 Gene3D G3DSA:3.40.50.300 368 551 1.0E-35 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS23820 9e32138197df54b7deec89d28f2162eb 552 Gene3D G3DSA:3.40.50.300 139 282 2.5E-40 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS23820 9e32138197df54b7deec89d28f2162eb 552 Gene3D G3DSA:3.40.50.300 8 107 2.5E-40 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS23820 9e32138197df54b7deec89d28f2162eb 552 SMART SM00382 29 239 1.8E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS23820 9e32138197df54b7deec89d28f2162eb 552 SMART SM00382 381 548 1.1E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS23820 9e32138197df54b7deec89d28f2162eb 552 SUPERFAMILY SSF52540 14 236 1.49E-39 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS01585 c3f8733d29d119391ec3c122010f68c7 456 SUPERFAMILY SSF55103 148 445 8.28E-13 T 06-07-2017 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CAK77_RS01585 c3f8733d29d119391ec3c122010f68c7 456 SUPERFAMILY SSF56176 43 171 1.36E-23 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAK77_RS01585 c3f8733d29d119391ec3c122010f68c7 456 Gene3D G3DSA:3.30.465.10 57 169 2.3E-9 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAK77_RS01585 c3f8733d29d119391ec3c122010f68c7 456 Pfam PF01565 FAD binding domain 49 139 2.0E-11 T 06-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CAK77_RS08680 a21ca61637be9b44a51680ab3a8672ac 464 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 261 298 - T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAK77_RS08680 a21ca61637be9b44a51680ab3a8672ac 464 Pfam PF00202 Aminotransferase class-III 47 456 2.0E-97 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAK77_RS08680 a21ca61637be9b44a51680ab3a8672ac 464 Gene3D G3DSA:3.90.1150.10 333 457 4.3E-34 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK77_RS08680 a21ca61637be9b44a51680ab3a8672ac 464 SUPERFAMILY SSF53383 26 457 9.49E-119 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK77_RS08680 a21ca61637be9b44a51680ab3a8672ac 464 Gene3D G3DSA:3.40.640.10 81 332 3.8E-81 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK77_RS01095 cb3f23e146e12a570d325f5da9be0a9f 1097 Pfam PF04602 Mycobacterial cell wall arabinan synthesis protein 16 665 4.5E-252 T 06-07-2017 IPR007680 Arabinofuranosyltransferase, N-terminal GO:0052636|GO:0071766 CAK77_RS01095 cb3f23e146e12a570d325f5da9be0a9f 1097 Gene3D G3DSA:2.60.120.610 36 210 1.2E-57 T 06-07-2017 IPR027451 Arabinofuranosyltransferase, domain 1 CAK77_RS01095 cb3f23e146e12a570d325f5da9be0a9f 1097 Pfam PF14896 EmbC C-terminal domain 700 1094 1.2E-145 T 06-07-2017 IPR032731 Arabinosyltransferase, C-terminal CAK77_RS12085 11d3cae858a2076f1c4ead92b37bd428 1808 Pfam PF00310 Glutamine amidotransferases class-II 14 409 1.6E-82 T 06-07-2017 IPR017932 Glutamine amidotransferase type 2 domain CAK77_RS12085 11d3cae858a2076f1c4ead92b37bd428 1808 Pfam PF04898 Glutamate synthase central domain 446 722 7.3E-71 T 06-07-2017 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 CAK77_RS12085 11d3cae858a2076f1c4ead92b37bd428 1808 Gene3D G3DSA:2.160.20.60 1394 1617 2.7E-62 T 06-07-2017 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 CAK77_RS12085 11d3cae858a2076f1c4ead92b37bd428 1808 Gene3D G3DSA:3.20.20.70 980 1332 2.9E-139 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK77_RS12085 11d3cae858a2076f1c4ead92b37bd428 1808 Gene3D G3DSA:3.20.20.70 435 766 1.9E-69 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK77_RS12085 11d3cae858a2076f1c4ead92b37bd428 1808 SUPERFAMILY SSF56235 14 413 1.83E-93 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAK77_RS12085 11d3cae858a2076f1c4ead92b37bd428 1808 Gene3D G3DSA:3.60.20.10 14 423 3.2E-102 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAK77_RS12085 11d3cae858a2076f1c4ead92b37bd428 1808 Pfam PF01493 GXGXG motif 1401 1563 3.3E-48 T 06-07-2017 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 CAK77_RS12085 11d3cae858a2076f1c4ead92b37bd428 1808 Pfam PF01645 Conserved region in glutamate synthase 976 1296 2.8E-100 T 06-07-2017 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 CAK77_RS12085 11d3cae858a2076f1c4ead92b37bd428 1808 SUPERFAMILY SSF51395 962 1313 1.95E-158 T 06-07-2017 CAK77_RS12085 11d3cae858a2076f1c4ead92b37bd428 1808 SUPERFAMILY SSF51395 438 801 1.95E-158 T 06-07-2017 CAK77_RS12085 11d3cae858a2076f1c4ead92b37bd428 1808 SUPERFAMILY SSF69336 1400 1610 1.31E-59 T 06-07-2017 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 CAK77_RS19080 4606bfa9395c9fcd1021e98da2d2a565 222 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 44 122 1.5E-16 T 06-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAK77_RS19080 4606bfa9395c9fcd1021e98da2d2a565 222 TIGRFAM TIGR00558 pdxH: pyridoxamine 5'-phosphate oxidase 31 222 7.8E-48 T 06-07-2017 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAK77_RS19080 4606bfa9395c9fcd1021e98da2d2a565 222 PIRSF PIRSF000190 20 222 3.3E-54 T 06-07-2017 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAK77_RS19080 4606bfa9395c9fcd1021e98da2d2a565 222 SUPERFAMILY SSF50475 26 222 5.11E-48 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS19080 4606bfa9395c9fcd1021e98da2d2a565 222 Pfam PF10590 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region 182 222 2.4E-10 T 06-07-2017 IPR019576 Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAK77_RS19080 4606bfa9395c9fcd1021e98da2d2a565 222 Gene3D G3DSA:2.30.110.10 28 222 3.0E-58 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS23465 2614941f5e084b57186726541f55124f 1178 Gene3D G3DSA:1.10.1200.10 658 733 1.1E-8 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS23465 2614941f5e084b57186726541f55124f 1178 SUPERFAMILY SSF51735 782 1090 3.86E-26 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS23465 2614941f5e084b57186726541f55124f 1178 Pfam PF07993 Male sterility protein 786 1047 3.3E-51 T 06-07-2017 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 CAK77_RS23465 2614941f5e084b57186726541f55124f 1178 Gene3D G3DSA:3.40.50.980 260 426 6.2E-18 T 06-07-2017 CAK77_RS23465 2614941f5e084b57186726541f55124f 1178 SMART SM00823 Phosphopantetheine attachment site 660 725 8.2E-4 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAK77_RS23465 2614941f5e084b57186726541f55124f 1178 Gene3D G3DSA:3.40.50.720 782 1014 1.3E-27 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS23465 2614941f5e084b57186726541f55124f 1178 Gene3D G3DSA:3.40.50.980 57 259 8.8E-24 T 06-07-2017 CAK77_RS23465 2614941f5e084b57186726541f55124f 1178 Pfam PF00550 Phosphopantetheine attachment site 662 728 2.4E-8 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS23465 2614941f5e084b57186726541f55124f 1178 SUPERFAMILY SSF56801 43 639 3.14E-86 T 06-07-2017 CAK77_RS23465 2614941f5e084b57186726541f55124f 1178 ProSitePatterns PS00455 Putative AMP-binding domain signature. 255 266 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK77_RS23465 2614941f5e084b57186726541f55124f 1178 TIGRFAM TIGR01746 Thioester-redct: thioester reductase domain 783 1176 4.6E-78 T 06-07-2017 IPR010080 Thioester reductase-like domain CAK77_RS23465 2614941f5e084b57186726541f55124f 1178 Pfam PF00501 AMP-binding enzyme 87 517 1.8E-63 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK77_RS23465 2614941f5e084b57186726541f55124f 1178 SUPERFAMILY SSF47336 657 742 5.23E-11 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS23465 2614941f5e084b57186726541f55124f 1178 Gene3D G3DSA:2.30.38.10 437 510 1.0E-11 T 06-07-2017 CAK77_RS10615 ad676c5235e6fbbccbc370019d2dfffc 75 SMART SM00248 15 44 0.002 T 06-07-2017 IPR002110 Ankyrin repeat GO:0005515 CAK77_RS10615 ad676c5235e6fbbccbc370019d2dfffc 75 Pfam PF13857 Ankyrin repeats (many copies) 4 55 7.9E-9 T 06-07-2017 CAK77_RS10615 ad676c5235e6fbbccbc370019d2dfffc 75 SUPERFAMILY SSF48403 7 69 9.48E-14 T 06-07-2017 IPR020683 Ankyrin repeat-containing domain CAK77_RS10615 ad676c5235e6fbbccbc370019d2dfffc 75 Gene3D G3DSA:1.25.40.20 7 72 1.8E-14 T 06-07-2017 IPR020683 Ankyrin repeat-containing domain CAK77_RS19100 876aa64d711b97ef6d0818bedf5dfd38 261 PIRSF PIRSF018982 2 253 2.5E-83 T 06-07-2017 IPR009246 Ethanolamine ammonia-lyase light chain GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 CAK77_RS19100 876aa64d711b97ef6d0818bedf5dfd38 261 Pfam PF05985 Ethanolamine ammonia-lyase light chain (EutC) 12 243 8.3E-83 T 06-07-2017 IPR009246 Ethanolamine ammonia-lyase light chain GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 CAK77_RS22090 74acf100f469a0fa4fced1d0445bb04d 144 Gene3D G3DSA:3.30.429.10 1 140 1.7E-53 T 06-07-2017 CAK77_RS22090 74acf100f469a0fa4fced1d0445bb04d 144 SUPERFAMILY SSF55331 1 118 2.07E-6 T 06-07-2017 IPR014347 Tautomerase/MIF superfamily CAK77_RS22090 74acf100f469a0fa4fced1d0445bb04d 144 Pfam PF14832 Putative oxalocrotonate tautomerase enzyme 1 136 3.1E-54 T 06-07-2017 IPR028116 Putative oxalocrotonate tautomerase CAK77_RS02765 b1b801e3d4fdf61f5ffb306c192c0f6d 522 Gene3D G3DSA:3.40.50.410 322 516 1.5E-6 T 06-07-2017 IPR002035 von Willebrand factor, type A CAK77_RS02765 b1b801e3d4fdf61f5ffb306c192c0f6d 522 Pfam PF13531 Bacterial extracellular solute-binding protein 31 277 3.7E-17 T 06-07-2017 CAK77_RS02765 b1b801e3d4fdf61f5ffb306c192c0f6d 522 SUPERFAMILY SSF53300 319 515 6.2E-17 T 06-07-2017 IPR002035 von Willebrand factor, type A CAK77_RS02765 b1b801e3d4fdf61f5ffb306c192c0f6d 522 Pfam PF00092 von Willebrand factor type A domain 321 493 4.4E-7 T 06-07-2017 IPR002035 von Willebrand factor, type A CAK77_RS02765 b1b801e3d4fdf61f5ffb306c192c0f6d 522 SMART SM00327 316 512 1.7E-4 T 06-07-2017 IPR002035 von Willebrand factor, type A CAK77_RS22290 98e61e7f40ca7fabc36b05609f50512e 499 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 169 194 3.1E-5 T 06-07-2017 CAK77_RS22290 98e61e7f40ca7fabc36b05609f50512e 499 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 3.1E-5 T 06-07-2017 CAK77_RS22290 98e61e7f40ca7fabc36b05609f50512e 499 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 5 202 9.5E-17 T 06-07-2017 CAK77_RS22290 98e61e7f40ca7fabc36b05609f50512e 499 Gene3D G3DSA:3.50.50.60 314 479 1.6E-16 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS22290 98e61e7f40ca7fabc36b05609f50512e 499 Gene3D G3DSA:3.50.50.60 3 248 4.2E-57 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS22290 98e61e7f40ca7fabc36b05609f50512e 499 SUPERFAMILY SSF51905 265 477 1.25E-21 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS22290 98e61e7f40ca7fabc36b05609f50512e 499 SUPERFAMILY SSF51905 2 210 8.48E-54 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS22290 98e61e7f40ca7fabc36b05609f50512e 499 SUPERFAMILY SSF51905 406 463 8.48E-54 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS11555 8f3ceeeefd9dfe0b61a649a70864e0ba 188 Pfam PF01453 D-mannose binding lectin 15 81 1.6E-15 T 06-07-2017 IPR001480 Bulb-type lectin domain CAK77_RS11555 8f3ceeeefd9dfe0b61a649a70864e0ba 188 Pfam PF01453 D-mannose binding lectin 54 113 8.0E-13 T 06-07-2017 IPR001480 Bulb-type lectin domain CAK77_RS11555 8f3ceeeefd9dfe0b61a649a70864e0ba 188 SUPERFAMILY SSF54106 139 187 9.29E-10 T 06-07-2017 IPR018392 LysM domain CAK77_RS11555 8f3ceeeefd9dfe0b61a649a70864e0ba 188 Gene3D G3DSA:2.90.10.10 2 110 5.8E-35 T 06-07-2017 IPR001480 Bulb-type lectin domain CAK77_RS11555 8f3ceeeefd9dfe0b61a649a70864e0ba 188 SMART SM00108 2 111 1.1E-29 T 06-07-2017 IPR001480 Bulb-type lectin domain CAK77_RS11555 8f3ceeeefd9dfe0b61a649a70864e0ba 188 SUPERFAMILY SSF51110 3 109 6.99E-27 T 06-07-2017 IPR001480 Bulb-type lectin domain CAK77_RS11555 8f3ceeeefd9dfe0b61a649a70864e0ba 188 SMART SM00257 140 187 1.4E-14 T 06-07-2017 IPR018392 LysM domain CAK77_RS11555 8f3ceeeefd9dfe0b61a649a70864e0ba 188 Pfam PF01476 LysM domain 141 187 1.0E-14 T 06-07-2017 IPR018392 LysM domain CAK77_RS11555 8f3ceeeefd9dfe0b61a649a70864e0ba 188 Gene3D G3DSA:3.10.350.10 138 187 9.2E-15 T 06-07-2017 IPR018392 LysM domain CAK77_RS09645 639bfcfaef5137ba92598ff542ec7f31 245 Gene3D G3DSA:3.40.1130.10 2 206 4.1E-33 T 06-07-2017 CAK77_RS09645 639bfcfaef5137ba92598ff542ec7f31 245 Pfam PF01553 Acyltransferase 21 151 9.4E-28 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CAK77_RS09645 639bfcfaef5137ba92598ff542ec7f31 245 SUPERFAMILY SSF69593 2 217 3.92E-52 T 06-07-2017 CAK77_RS09645 639bfcfaef5137ba92598ff542ec7f31 245 SMART SM00563 35 154 8.6E-34 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CAK77_RS11570 3752879cc08f4cb98dfb4fde724f2938 132 SUPERFAMILY SSF50475 11 103 2.22E-17 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS11570 3752879cc08f4cb98dfb4fde724f2938 132 TIGRFAM TIGR03666 Rv2061_F420: PPOX class probable F420-dependent enzyme, Rv2061 family 1 126 6.1E-43 T 06-07-2017 IPR019965 PPOX class F420-dependent enzyme, family Rv2061, putative CAK77_RS11570 3752879cc08f4cb98dfb4fde724f2938 132 Gene3D G3DSA:2.30.110.10 12 101 2.0E-11 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS11570 3752879cc08f4cb98dfb4fde724f2938 132 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 11 61 2.1E-8 T 06-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAK77_RS12580 34318048bffbbfc961f40dc3adc505ab 112 Gene3D G3DSA:3.10.450.50 6 79 6.6E-8 T 06-07-2017 IPR032710 NTF2-like domain CAK77_RS12580 34318048bffbbfc961f40dc3adc505ab 112 Pfam PF12680 SnoaL-like domain 12 77 5.0E-7 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain CAK77_RS12580 34318048bffbbfc961f40dc3adc505ab 112 SUPERFAMILY SSF54427 6 101 2.54E-11 T 06-07-2017 IPR032710 NTF2-like domain CAK77_RS16330 9f0dba3c0b8024d3183c395f22543fb5 65 Gene3D G3DSA:4.10.1160.10 19 64 1.0E-21 T 06-07-2017 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS16330 9f0dba3c0b8024d3183c395f22543fb5 65 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 58 2.4E-22 T 06-07-2017 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS16330 9f0dba3c0b8024d3183c395f22543fb5 65 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 64 17.346 T 06-07-2017 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS16330 9f0dba3c0b8024d3183c395f22543fb5 65 SUPERFAMILY SSF143800 1 64 7.26E-23 T 06-07-2017 CAK77_RS16330 9f0dba3c0b8024d3183c395f22543fb5 65 Pfam PF00830 Ribosomal L28 family 4 60 4.9E-22 T 06-07-2017 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS22300 c9bf39207f7796fede02eb60b6f238f7 280 Gene3D G3DSA:3.40.50.720 19 244 2.3E-56 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS22300 c9bf39207f7796fede02eb60b6f238f7 280 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 144 152 9.7E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS22300 c9bf39207f7796fede02eb60b6f238f7 280 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 90 101 9.7E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS22300 c9bf39207f7796fede02eb60b6f238f7 280 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 164 183 9.7E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS22300 c9bf39207f7796fede02eb60b6f238f7 280 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 151 179 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK77_RS22300 c9bf39207f7796fede02eb60b6f238f7 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 183 1.0E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS22300 c9bf39207f7796fede02eb60b6f238f7 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 138 154 1.0E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS22300 c9bf39207f7796fede02eb60b6f238f7 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 90 101 1.0E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS22300 c9bf39207f7796fede02eb60b6f238f7 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 18 35 1.0E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS22300 c9bf39207f7796fede02eb60b6f238f7 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 185 202 1.0E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS22300 c9bf39207f7796fede02eb60b6f238f7 280 Pfam PF00106 short chain dehydrogenase 19 203 9.8E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS22300 c9bf39207f7796fede02eb60b6f238f7 280 SUPERFAMILY SSF51735 19 268 1.2E-57 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS16785 f537fd3bb6d55918428e8257ba996735 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 58 73 1.1E-6 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK77_RS16785 f537fd3bb6d55918428e8257ba996735 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 11 26 1.1E-6 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK77_RS16785 f537fd3bb6d55918428e8257ba996735 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 43 58 1.1E-6 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK77_RS16785 f537fd3bb6d55918428e8257ba996735 111 Pfam PF12840 Helix-turn-helix domain 8 67 1.3E-10 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS16785 f537fd3bb6d55918428e8257ba996735 111 Gene3D G3DSA:1.10.10.10 4 107 9.8E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS16785 f537fd3bb6d55918428e8257ba996735 111 SMART SM00418 9 83 2.6E-12 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK77_RS16785 f537fd3bb6d55918428e8257ba996735 111 SUPERFAMILY SSF46785 5 100 1.25E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS00570 bd2d0254cf02f896dfc24362d9fb4415 144 SMART SM00347 26 126 2.9E-17 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK77_RS00570 bd2d0254cf02f896dfc24362d9fb4415 144 Pfam PF01047 MarR family 36 83 4.1E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK77_RS00570 bd2d0254cf02f896dfc24362d9fb4415 144 SUPERFAMILY SSF46785 7 137 3.2E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS00570 bd2d0254cf02f896dfc24362d9fb4415 144 Gene3D G3DSA:1.10.10.10 4 137 9.7E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS22595 e258b4bd71b6dbd60de21c665baceb09 525 SUPERFAMILY SSF52096 15 259 1.33E-70 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS22595 e258b4bd71b6dbd60de21c665baceb09 525 SUPERFAMILY SSF52096 227 507 7.16E-90 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS22595 e258b4bd71b6dbd60de21c665baceb09 525 Gene3D G3DSA:3.90.226.10 270 516 1.9E-94 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS22595 e258b4bd71b6dbd60de21c665baceb09 525 Gene3D G3DSA:3.90.226.10 18 260 9.7E-79 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS22595 e258b4bd71b6dbd60de21c665baceb09 525 Pfam PF01039 Carboxyl transferase domain 38 512 1.4E-152 T 06-07-2017 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAK77_RS15130 0116997e2b8440a90d2df7b4bd47b81d 177 SUPERFAMILY SSF55729 1 161 9.29E-32 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS15130 0116997e2b8440a90d2df7b4bd47b81d 177 Pfam PF13420 Acetyltransferase (GNAT) domain 3 153 2.6E-29 T 06-07-2017 CAK77_RS15130 0116997e2b8440a90d2df7b4bd47b81d 177 Gene3D G3DSA:3.40.630.30 1 162 1.5E-39 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS01980 82f23ca0a4bec16ed838a135fdf1fd7e 232 Gene3D G3DSA:3.40.50.150 31 200 8.5E-34 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS01980 82f23ca0a4bec16ed838a135fdf1fd7e 232 SUPERFAMILY SSF53335 29 195 3.07E-32 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS01980 82f23ca0a4bec16ed838a135fdf1fd7e 232 Pfam PF13847 Methyltransferase domain 53 157 3.4E-15 T 06-07-2017 IPR025714 Methyltransferase domain CAK77_RS11510 77b7bae9b299791f00c9e115db8306f7 574 TIGRFAM TIGR00337 PyrG: CTP synthase 22 557 1.3E-226 T 06-07-2017 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 CAK77_RS11510 77b7bae9b299791f00c9e115db8306f7 574 Gene3D G3DSA:3.40.50.880 312 562 1.7E-88 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAK77_RS11510 77b7bae9b299791f00c9e115db8306f7 574 Gene3D G3DSA:3.40.50.300 18 309 1.1E-129 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS11510 77b7bae9b299791f00c9e115db8306f7 574 SUPERFAMILY SSF52540 22 291 5.38E-118 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS11510 77b7bae9b299791f00c9e115db8306f7 574 Pfam PF06418 CTP synthase N-terminus 23 291 1.5E-121 T 06-07-2017 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 CAK77_RS11510 77b7bae9b299791f00c9e115db8306f7 574 SUPERFAMILY SSF52317 314 562 2.29E-73 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAK77_RS11510 77b7bae9b299791f00c9e115db8306f7 574 Pfam PF00117 Glutamine amidotransferase class-I 326 556 9.1E-48 T 06-07-2017 IPR017926 Glutamine amidotransferase CAK77_RS11510 77b7bae9b299791f00c9e115db8306f7 574 Hamap MF_01227 CTP synthase [pyrG]. 22 562 49.461 T 06-07-2017 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 CAK77_RS15275 5616a460976aa8b3d682abb283f50930 116 Gene3D G3DSA:1.10.260.40 9 76 1.1E-14 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK77_RS15275 5616a460976aa8b3d682abb283f50930 116 SMART SM00530 12 67 1.3E-8 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAK77_RS15275 5616a460976aa8b3d682abb283f50930 116 Pfam PF13560 Helix-turn-helix domain 8 67 1.5E-11 T 06-07-2017 CAK77_RS15275 5616a460976aa8b3d682abb283f50930 116 SUPERFAMILY SSF47413 4 72 5.07E-13 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK77_RS20315 525a20f807826296d501b331d11ef4d6 523 SUPERFAMILY SSF56801 29 522 3.01E-139 T 06-07-2017 CAK77_RS20315 525a20f807826296d501b331d11ef4d6 523 Pfam PF00501 AMP-binding enzyme 29 430 2.0E-94 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK77_RS20315 525a20f807826296d501b331d11ef4d6 523 Gene3D G3DSA:3.30.300.30 427 522 5.9E-30 T 06-07-2017 CAK77_RS20315 525a20f807826296d501b331d11ef4d6 523 ProSitePatterns PS00455 Putative AMP-binding domain signature. 177 188 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK77_RS20315 525a20f807826296d501b331d11ef4d6 523 Gene3D G3DSA:2.30.38.10 342 421 7.6E-23 T 06-07-2017 CAK77_RS20315 525a20f807826296d501b331d11ef4d6 523 Gene3D G3DSA:3.40.50.980 184 341 2.8E-49 T 06-07-2017 CAK77_RS20315 525a20f807826296d501b331d11ef4d6 523 Pfam PF13193 AMP-binding enzyme C-terminal domain 439 513 2.4E-18 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAK77_RS20315 525a20f807826296d501b331d11ef4d6 523 Gene3D G3DSA:3.40.50.980 29 183 3.6E-29 T 06-07-2017 CAK77_RS16640 d7379a1dd1822bbc7a86af24fd5ecf25 135 SUPERFAMILY SSF142906 16 130 5.36E-17 T 06-07-2017 CAK77_RS16640 d7379a1dd1822bbc7a86af24fd5ecf25 135 Pfam PF04237 YjbR 23 121 2.4E-18 T 06-07-2017 IPR007351 Uncharacterised protein YjbR CAK77_RS07620 800831b3562942a723b3b5a4ad6789f0 135 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 3 128 20.802 T 06-07-2017 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CAK77_RS07620 800831b3562942a723b3b5a4ad6789f0 135 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 2 128 3.4E-36 T 06-07-2017 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CAK77_RS07620 800831b3562942a723b3b5a4ad6789f0 135 Gene3D G3DSA:3.90.470.20 2 127 2.3E-41 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CAK77_RS07620 800831b3562942a723b3b5a4ad6789f0 135 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 8 128 1.0E-11 T 06-07-2017 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CAK77_RS07620 800831b3562942a723b3b5a4ad6789f0 135 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 4 101 1.7E-17 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CAK77_RS07620 800831b3562942a723b3b5a4ad6789f0 135 SUPERFAMILY SSF56214 2 127 3.66E-22 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CAK77_RS14200 d4fb9f88146d79cf2d4b4db6aaf3ba76 160 Pfam PF09348 Domain of unknown function (DUF1990) 7 159 4.4E-53 T 06-07-2017 IPR018960 Domain of unknown function DUF1990 CAK77_RS14200 d4fb9f88146d79cf2d4b4db6aaf3ba76 160 PIRSF PIRSF010260 1 160 1.1E-48 T 06-07-2017 IPR014457 Uncharacterised conserved protein UCP010260 CAK77_RS21080 5e47a15ccdc35e463a6414baf9714aa2 513 Pfam PF13520 Amino acid permease 31 451 3.9E-35 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CAK77_RS21080 5e47a15ccdc35e463a6414baf9714aa2 513 PIRSF PIRSF006060 11 504 1.7E-57 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CAK77_RS02390 cfc97020bc5bbf58eb0e7d51835da3b1 357 Gene3D G3DSA:3.40.50.300 123 348 2.7E-17 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS02390 cfc97020bc5bbf58eb0e7d51835da3b1 357 SUPERFAMILY SSF52540 124 347 2.88E-17 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS02390 cfc97020bc5bbf58eb0e7d51835da3b1 357 TIGRFAM TIGR03815 CpaE_hom_Actino: helicase/secretion neighborhood CpaE-like protein 13 346 4.1E-99 T 06-07-2017 IPR022521 Conserved hypothetical protein CHP03815, CpaE-like CAK77_RS05755 46ca71d3ab7cd23cb88e3ae7a38414f7 419 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 52 406 3.5E-89 T 06-07-2017 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 CAK77_RS05755 46ca71d3ab7cd23cb88e3ae7a38414f7 419 Pfam PF04261 Dyp-type peroxidase family 52 406 2.0E-103 T 06-07-2017 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 CAK77_RS05755 46ca71d3ab7cd23cb88e3ae7a38414f7 419 TIGRFAM TIGR01412 tat_substr_1: Tat-translocated enzyme 3 418 3.4E-150 T 06-07-2017 IPR006313 Deferrochelatase/peroxidase EfeB GO:0004601|GO:0015684|GO:0020037|GO:0033212 CAK77_RS05755 46ca71d3ab7cd23cb88e3ae7a38414f7 419 SUPERFAMILY SSF54909 47 413 1.97E-88 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAK77_RS11085 df3e9cdef224efb78d5149cfde499409 165 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 14 134 2.0E-21 T 06-07-2017 IPR005031 Coenzyme Q-binding protein COQ10, START domain CAK77_RS11085 df3e9cdef224efb78d5149cfde499409 165 SUPERFAMILY SSF55961 13 134 2.02E-19 T 06-07-2017 CAK77_RS11085 df3e9cdef224efb78d5149cfde499409 165 Gene3D G3DSA:3.30.530.20 13 136 7.7E-19 T 06-07-2017 IPR023393 START-like domain CAK77_RS16250 bd09541761fc43e4a3e0c9add8b59b5f 299 Gene3D G3DSA:3.40.50.1820 76 297 2.7E-43 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS16250 bd09541761fc43e4a3e0c9add8b59b5f 299 SUPERFAMILY SSF53474 77 298 3.62E-35 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS16250 bd09541761fc43e4a3e0c9add8b59b5f 299 Pfam PF01738 Dienelactone hydrolase family 94 297 1.8E-37 T 06-07-2017 IPR002925 Dienelactone hydrolase GO:0016787 CAK77_RS09665 a00a1efd8796141cb5b5552e13e7c735 434 Pfam PF00069 Protein kinase domain 24 269 6.5E-47 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CAK77_RS09665 a00a1efd8796141cb5b5552e13e7c735 434 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 142 154 - T 06-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CAK77_RS09665 a00a1efd8796141cb5b5552e13e7c735 434 Gene3D G3DSA:1.10.510.10 89 272 6.2E-48 T 06-07-2017 CAK77_RS09665 a00a1efd8796141cb5b5552e13e7c735 434 SUPERFAMILY SSF56112 20 279 7.49E-74 T 06-07-2017 IPR011009 Protein kinase-like domain CAK77_RS09665 a00a1efd8796141cb5b5552e13e7c735 434 Gene3D G3DSA:3.30.200.20 15 88 2.4E-23 T 06-07-2017 CAK77_RS09665 a00a1efd8796141cb5b5552e13e7c735 434 SMART SM00220 23 282 2.1E-58 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CAK77_RS13530 6dbc1cd41718a1497ffd56dd8f7e9959 516 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 34 217 7.9E-63 T 06-07-2017 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CAK77_RS13530 6dbc1cd41718a1497ffd56dd8f7e9959 516 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 30 515 4.2E-199 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CAK77_RS13530 6dbc1cd41718a1497ffd56dd8f7e9959 516 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 30 515 86.402 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CAK77_RS13530 6dbc1cd41718a1497ffd56dd8f7e9959 516 PIRSF PIRSF000110 11 516 1.0E-176 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CAK77_RS13530 6dbc1cd41718a1497ffd56dd8f7e9959 516 SUPERFAMILY SSF51735 20 220 5.91E-63 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS13530 6dbc1cd41718a1497ffd56dd8f7e9959 516 ProSitePatterns PS00069 Glucose-6-phosphate dehydrogenase active site. 207 213 - T 06-07-2017 IPR019796 Glucose-6-phosphate dehydrogenase, active site GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CAK77_RS13530 6dbc1cd41718a1497ffd56dd8f7e9959 516 SUPERFAMILY SSF55347 207 514 1.8E-107 T 06-07-2017 CAK77_RS13530 6dbc1cd41718a1497ffd56dd8f7e9959 516 Gene3D G3DSA:3.30.360.10 217 514 1.7E-114 T 06-07-2017 CAK77_RS13530 6dbc1cd41718a1497ffd56dd8f7e9959 516 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 267 283 2.7E-48 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CAK77_RS13530 6dbc1cd41718a1497ffd56dd8f7e9959 516 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 356 382 2.7E-48 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CAK77_RS13530 6dbc1cd41718a1497ffd56dd8f7e9959 516 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 249 266 2.7E-48 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CAK77_RS13530 6dbc1cd41718a1497ffd56dd8f7e9959 516 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 197 225 2.7E-48 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CAK77_RS13530 6dbc1cd41718a1497ffd56dd8f7e9959 516 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 173 186 2.7E-48 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CAK77_RS13530 6dbc1cd41718a1497ffd56dd8f7e9959 516 Gene3D G3DSA:3.40.50.720 29 216 5.3E-70 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS13530 6dbc1cd41718a1497ffd56dd8f7e9959 516 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 219 514 5.8E-107 T 06-07-2017 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CAK77_RS18280 73c7a9c6476d9f6eed380fc1c781addb 362 SUPERFAMILY SSF51556 7 351 4.13E-70 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK77_RS18280 73c7a9c6476d9f6eed380fc1c781addb 362 Gene3D G3DSA:3.20.20.140 10 352 7.1E-99 T 06-07-2017 CAK77_RS18280 73c7a9c6476d9f6eed380fc1c781addb 362 Hamap MF_00540 Adenosine deaminase [add]. 8 353 53.524 T 06-07-2017 IPR028893 Adenosine deaminase GO:0004000|GO:0009168 KEGG: 00230+3.5.4.4|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-74217 CAK77_RS18280 73c7a9c6476d9f6eed380fc1c781addb 362 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 14 350 3.6E-71 T 06-07-2017 IPR006330 Adenosine/adenine deaminase GO:0019239 Reactome: R-HSA-74217 CAK77_RS18280 73c7a9c6476d9f6eed380fc1c781addb 362 Pfam PF00962 Adenosine/AMP deaminase 13 350 3.6E-94 T 06-07-2017 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 CAK77_RS02780 a294403fbee7f8e572a012284f7c405f 204 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 129 139 - T 06-07-2017 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 CAK77_RS02780 a294403fbee7f8e572a012284f7c405f 204 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 19 202 41.443 T 06-07-2017 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 CAK77_RS02780 a294403fbee7f8e572a012284f7c405f 204 Pfam PF01227 GTP cyclohydrolase I 24 201 4.7E-76 T 06-07-2017 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 CAK77_RS02780 a294403fbee7f8e572a012284f7c405f 204 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 25 201 1.6E-72 T 06-07-2017 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 CAK77_RS02780 a294403fbee7f8e572a012284f7c405f 204 SUPERFAMILY SSF55620 13 201 2.22E-75 T 06-07-2017 CAK77_RS02780 a294403fbee7f8e572a012284f7c405f 204 Gene3D G3DSA:1.10.286.10 18 70 4.3E-23 T 06-07-2017 CAK77_RS02780 a294403fbee7f8e572a012284f7c405f 204 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 79 95 - T 06-07-2017 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 CAK77_RS02780 a294403fbee7f8e572a012284f7c405f 204 Gene3D G3DSA:3.30.1130.10 72 202 1.4E-58 T 06-07-2017 CAK77_RS15385 5706072082b8c721934b3977c808f05c 266 Gene3D G3DSA:3.30.572.10 7 266 4.5E-125 T 06-07-2017 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 CAK77_RS15385 5706072082b8c721934b3977c808f05c 266 SUPERFAMILY SSF55831 6 266 2.75E-121 T 06-07-2017 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 CAK77_RS15385 5706072082b8c721934b3977c808f05c 266 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 6 88 1.5E-36 T 06-07-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 CAK77_RS15385 5706072082b8c721934b3977c808f05c 266 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 88 266 5.5E-90 T 06-07-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 CAK77_RS15385 5706072082b8c721934b3977c808f05c 266 ProSitePatterns PS00091 Thymidylate synthase active site. 129 157 - T 06-07-2017 IPR020940 Thymidylate synthase, active site GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 CAK77_RS15385 5706072082b8c721934b3977c808f05c 266 PRINTS PR00108 Thymidylate synthase family signature 118 137 5.3E-48 T 06-07-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 CAK77_RS15385 5706072082b8c721934b3977c808f05c 266 PRINTS PR00108 Thymidylate synthase family signature 45 66 5.3E-48 T 06-07-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 CAK77_RS15385 5706072082b8c721934b3977c808f05c 266 PRINTS PR00108 Thymidylate synthase family signature 144 159 5.3E-48 T 06-07-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 CAK77_RS15385 5706072082b8c721934b3977c808f05c 266 PRINTS PR00108 Thymidylate synthase family signature 200 217 5.3E-48 T 06-07-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 CAK77_RS15385 5706072082b8c721934b3977c808f05c 266 PRINTS PR00108 Thymidylate synthase family signature 162 188 5.3E-48 T 06-07-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 CAK77_RS15385 5706072082b8c721934b3977c808f05c 266 Pfam PF00303 Thymidylate synthase 6 266 5.4E-118 T 06-07-2017 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 CAK77_RS15385 5706072082b8c721934b3977c808f05c 266 Hamap MF_00008 Thymidylate synthase [thyA]. 4 266 38.437 T 06-07-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 CAK77_RS21200 d2a74d3936a163fc366529c80c517204 337 TIGRFAM TIGR03557 F420_G6P_family: F420-dependent oxidoreductase, G6PDH family 7 334 1.6E-76 T 06-07-2017 IPR019945 F420-dependent glucose-6-phosphate dehydrogenase-related CAK77_RS21200 d2a74d3936a163fc366529c80c517204 337 SUPERFAMILY SSF51679 5 334 1.57E-70 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS21200 d2a74d3936a163fc366529c80c517204 337 Hamap MF_02123 F420-dependent glucose-6-phosphate dehydrogenase [fgd]. 4 336 69.086 T 06-07-2017 IPR019944 F420-dependent glucose-6-phosphate dehydrogenase CAK77_RS21200 d2a74d3936a163fc366529c80c517204 337 Pfam PF00296 Luciferase-like monooxygenase 12 308 1.0E-67 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS21200 d2a74d3936a163fc366529c80c517204 337 TIGRFAM TIGR03554 F420_G6P_DH: glucose-6-phosphate dehydrogenase (coenzyme-F420) 4 334 3.9E-211 T 06-07-2017 IPR019944 F420-dependent glucose-6-phosphate dehydrogenase CAK77_RS21200 d2a74d3936a163fc366529c80c517204 337 Gene3D G3DSA:3.20.20.30 5 335 4.5E-82 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS24180 8339637bb912630e834f99ca7ed86b0b 435 SUPERFAMILY SSF51230 2 91 2.54E-24 T 06-07-2017 IPR011053 Single hybrid motif CAK77_RS24180 8339637bb912630e834f99ca7ed86b0b 435 Gene3D G3DSA:2.40.50.100 5 81 1.3E-22 T 06-07-2017 CAK77_RS24180 8339637bb912630e834f99ca7ed86b0b 435 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 207 432 1.0E-77 T 06-07-2017 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CAK77_RS24180 8339637bb912630e834f99ca7ed86b0b 435 Pfam PF00364 Biotin-requiring enzyme 5 77 6.4E-18 T 06-07-2017 IPR000089 Biotin/lipoyl attachment CAK77_RS24180 8339637bb912630e834f99ca7ed86b0b 435 SUPERFAMILY SSF52777 202 433 1.96E-76 T 06-07-2017 CAK77_RS24180 8339637bb912630e834f99ca7ed86b0b 435 Gene3D G3DSA:4.10.320.10 140 187 2.4E-15 T 06-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CAK77_RS24180 8339637bb912630e834f99ca7ed86b0b 435 Gene3D G3DSA:3.30.559.10 199 433 6.0E-82 T 06-07-2017 IPR023213 Chloramphenicol acetyltransferase-like domain Reactome: R-HSA-389661 CAK77_RS24180 8339637bb912630e834f99ca7ed86b0b 435 SUPERFAMILY SSF47005 140 181 6.54E-10 T 06-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CAK77_RS24180 8339637bb912630e834f99ca7ed86b0b 435 Pfam PF02817 e3 binding domain 144 177 2.0E-11 T 06-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CAK77_RS13880 44db2d71136c0d970ef48fdded98a399 359 PRINTS PR00599 Methionine aminopeptidase-1 signature 212 228 2.8E-5 T 06-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase CAK77_RS13880 44db2d71136c0d970ef48fdded98a399 359 PRINTS PR00599 Methionine aminopeptidase-1 signature 310 322 2.8E-5 T 06-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase CAK77_RS13880 44db2d71136c0d970ef48fdded98a399 359 PRINTS PR00599 Methionine aminopeptidase-1 signature 190 203 2.8E-5 T 06-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase CAK77_RS13880 44db2d71136c0d970ef48fdded98a399 359 Gene3D G3DSA:3.40.350.10 2 128 5.3E-23 T 06-07-2017 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal CAK77_RS13880 44db2d71136c0d970ef48fdded98a399 359 Pfam PF00557 Metallopeptidase family M24 139 341 9.5E-62 T 06-07-2017 IPR000994 Peptidase M24, structural domain CAK77_RS13880 44db2d71136c0d970ef48fdded98a399 359 SUPERFAMILY SSF53092 2 128 2.44E-22 T 06-07-2017 IPR028980 Creatinase/Aminopeptidase P, N-terminal CAK77_RS13880 44db2d71136c0d970ef48fdded98a399 359 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 288 300 - T 06-07-2017 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site CAK77_RS13880 44db2d71136c0d970ef48fdded98a399 359 SUPERFAMILY SSF55920 130 358 1.7E-73 T 06-07-2017 IPR000994 Peptidase M24, structural domain CAK77_RS13880 44db2d71136c0d970ef48fdded98a399 359 Pfam PF01321 Creatinase/Prolidase N-terminal domain 3 130 7.2E-23 T 06-07-2017 IPR000587 Creatinase, N-terminal GO:0016787 CAK77_RS13880 44db2d71136c0d970ef48fdded98a399 359 Gene3D G3DSA:3.90.230.10 130 358 1.2E-76 T 06-07-2017 IPR000994 Peptidase M24, structural domain CAK77_RS04055 13c45c89962ec09e5ab47be8d6bf9ba4 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 73 2.8E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS04055 13c45c89962ec09e5ab47be8d6bf9ba4 210 Gene3D G3DSA:1.10.357.10 18 195 4.9E-21 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS04055 13c45c89962ec09e5ab47be8d6bf9ba4 210 SUPERFAMILY SSF46689 18 85 6.48E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS03475 9e048ad21a16629df769d7a0d9908e81 115 Pfam PF02656 Domain of unknown function (DUF202) 14 79 7.0E-16 T 06-07-2017 IPR003807 Domain of unknown function DUF202 CAK77_RS20955 c9f488f96f9455047a72c90b1df8776e 317 PIRSF PIRSF002936 16 317 4.7E-140 T 06-07-2017 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 CAK77_RS20955 c9f488f96f9455047a72c90b1df8776e 317 SUPERFAMILY SSF52402 19 225 2.87E-67 T 06-07-2017 CAK77_RS20955 c9f488f96f9455047a72c90b1df8776e 317 TIGRFAM TIGR02039 CysD: sulfate adenylyltransferase, small subunit 24 317 4.7E-137 T 06-07-2017 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 CAK77_RS20955 c9f488f96f9455047a72c90b1df8776e 317 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 45 271 1.5E-49 T 06-07-2017 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 CAK77_RS20955 c9f488f96f9455047a72c90b1df8776e 317 Gene3D G3DSA:3.40.50.620 17 225 1.1E-52 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS20955 c9f488f96f9455047a72c90b1df8776e 317 Gene3D G3DSA:3.40.50.620 258 265 1.1E-52 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS03705 e001fb662db0dc4bad33f64d40dbcf7d 323 Pfam PF01370 NAD dependent epimerase/dehydratase family 5 226 9.9E-31 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 CAK77_RS03705 e001fb662db0dc4bad33f64d40dbcf7d 323 Gene3D G3DSA:3.40.50.720 1 314 1.3E-49 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS03705 e001fb662db0dc4bad33f64d40dbcf7d 323 SUPERFAMILY SSF51735 1 318 1.87E-56 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS15665 44519acf085bb80f74ea4ab638040a07 143 Pfam PF05423 Mycobacterium membrane protein 5 143 1.8E-58 T 06-07-2017 IPR008693 Transport accessory protein MmpS CAK77_RS18400 6799d0c78f849369176b2f2bc7d1b11e 392 Gene3D G3DSA:3.20.20.70 304 386 5.5E-96 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK77_RS18400 6799d0c78f849369176b2f2bc7d1b11e 392 Gene3D G3DSA:3.20.20.70 10 263 5.5E-96 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK77_RS18400 6799d0c78f849369176b2f2bc7d1b11e 392 SUPERFAMILY SSF51395 301 385 3.38E-92 T 06-07-2017 CAK77_RS18400 6799d0c78f849369176b2f2bc7d1b11e 392 SUPERFAMILY SSF51395 9 266 3.38E-92 T 06-07-2017 CAK77_RS18400 6799d0c78f849369176b2f2bc7d1b11e 392 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 13 248 9.5E-44 T 06-07-2017 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 CAK77_RS18400 6799d0c78f849369176b2f2bc7d1b11e 392 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 315 368 4.5E-5 T 06-07-2017 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 CAK77_RS21295 28dde83b7484c6e348315e5f256ca6a0 182 PIRSF PIRSF005859 24 182 1.8E-45 T 06-07-2017 IPR004307 TspO/MBR-related protein GO:0016021 CAK77_RS21295 28dde83b7484c6e348315e5f256ca6a0 182 Pfam PF03073 TspO/MBR family 38 178 5.4E-40 T 06-07-2017 IPR004307 TspO/MBR-related protein GO:0016021 CAK77_RS12365 80474648edcb01b395ee55902f86a964 327 Gene3D G3DSA:1.10.620.20 2 312 1.6E-110 T 06-07-2017 IPR012348 Ribonucleotide reductase-related GO:0016491|GO:0055114 Reactome: R-HSA-499943 CAK77_RS12365 80474648edcb01b395ee55902f86a964 327 PIRSF PIRSF000346 1 326 3.1E-103 T 06-07-2017 IPR005067 Fatty acid desaturase, type 2 GO:0006631|GO:0045300|GO:0055114 CAK77_RS12365 80474648edcb01b395ee55902f86a964 327 SUPERFAMILY SSF47240 2 313 6.87E-87 T 06-07-2017 IPR009078 Ferritin-like superfamily CAK77_RS12365 80474648edcb01b395ee55902f86a964 327 Pfam PF03405 Fatty acid desaturase 7 316 2.8E-84 T 06-07-2017 IPR005067 Fatty acid desaturase, type 2 GO:0006631|GO:0045300|GO:0055114 CAK77_RS18845 b0d85fc2b15c4b9f76c85ef3f8fc826c 514 Pfam PF01145 SPFH domain / Band 7 family 31 209 3.2E-24 T 06-07-2017 IPR001107 Band 7 domain CAK77_RS18845 b0d85fc2b15c4b9f76c85ef3f8fc826c 514 SUPERFAMILY SSF117892 57 199 1.19E-30 T 06-07-2017 IPR001107 Band 7 domain CAK77_RS18845 b0d85fc2b15c4b9f76c85ef3f8fc826c 514 SMART SM00244 27 192 1.6E-5 T 06-07-2017 IPR001107 Band 7 domain CAK77_RS18845 b0d85fc2b15c4b9f76c85ef3f8fc826c 514 Pfam PF15975 Flotillin 375 473 1.3E-8 T 06-07-2017 IPR031905 Flotillin, C-terminal domain Reactome: R-HSA-8849932 CAK77_RS04075 c1ef559a8b665242ffe60f8738451d64 306 Gene3D G3DSA:2.120.10.30 162 300 5.0E-16 T 06-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like CAK77_RS04075 c1ef559a8b665242ffe60f8738451d64 306 Gene3D G3DSA:2.120.10.30 10 161 1.4E-15 T 06-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like CAK77_RS04075 c1ef559a8b665242ffe60f8738451d64 306 SUPERFAMILY SSF63825 4 185 5.49E-16 T 06-07-2017 CAK77_RS04075 c1ef559a8b665242ffe60f8738451d64 306 SMART SM00135 90 133 15.0 T 06-07-2017 IPR000033 LDLR class B repeat CAK77_RS04075 c1ef559a8b665242ffe60f8738451d64 306 SMART SM00135 249 290 27.0 T 06-07-2017 IPR000033 LDLR class B repeat CAK77_RS04075 c1ef559a8b665242ffe60f8738451d64 306 SMART SM00135 26 89 1.1 T 06-07-2017 IPR000033 LDLR class B repeat CAK77_RS04075 c1ef559a8b665242ffe60f8738451d64 306 SUPERFAMILY SSF63829 110 303 5.56E-14 T 06-07-2017 CAK77_RS01655 050016f97ab0f3def75134cc35b98b32 352 SUPERFAMILY SSF56112 16 341 3.97E-47 T 06-07-2017 IPR011009 Protein kinase-like domain CAK77_RS01655 050016f97ab0f3def75134cc35b98b32 352 Gene3D G3DSA:3.90.1200.10 135 343 2.9E-31 T 06-07-2017 CAK77_RS01655 050016f97ab0f3def75134cc35b98b32 352 Pfam PF01636 Phosphotransferase enzyme family 38 268 6.4E-32 T 06-07-2017 IPR002575 Aminoglycoside phosphotransferase CAK77_RS04025 d7407417be6061700dc53f86e4255d9d 308 Pfam PF13602 Zinc-binding dehydrogenase 247 306 1.7E-12 T 06-07-2017 CAK77_RS04025 d7407417be6061700dc53f86e4255d9d 308 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 123 4.9E-8 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAK77_RS04025 d7407417be6061700dc53f86e4255d9d 308 Gene3D G3DSA:3.90.180.10 2 147 2.2E-43 T 06-07-2017 IPR011032 GroES-like CAK77_RS04025 d7407417be6061700dc53f86e4255d9d 308 Gene3D G3DSA:3.40.50.720 148 225 3.6E-11 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS04025 d7407417be6061700dc53f86e4255d9d 308 SUPERFAMILY SSF51735 116 229 2.47E-24 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS04025 d7407417be6061700dc53f86e4255d9d 308 SUPERFAMILY SSF50129 2 148 8.98E-35 T 06-07-2017 IPR011032 GroES-like CAK77_RS04025 d7407417be6061700dc53f86e4255d9d 308 SMART SM00829 11 306 1.2E-14 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAK77_RS00070 75389d53b54d328e1963b2138d444b08 278 SUPERFAMILY SSF54001 5 270 1.42E-64 T 06-07-2017 CAK77_RS00070 75389d53b54d328e1963b2138d444b08 278 Pfam PF00797 N-acetyltransferase 25 265 2.0E-51 T 06-07-2017 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 CAK77_RS00070 75389d53b54d328e1963b2138d444b08 278 Gene3D G3DSA:3.30.2140.10 193 274 2.0E-42 T 06-07-2017 CAK77_RS00070 75389d53b54d328e1963b2138d444b08 278 Gene3D G3DSA:3.30.2140.10 7 89 2.0E-42 T 06-07-2017 CAK77_RS06280 516b044d480b0bb7ef244fd4e58b0f56 208 Pfam PF14030 Protein of unknown function (DUF4245) 28 200 3.7E-51 T 06-07-2017 IPR025339 Protein of unknown function DUF4245 CAK77_RS07305 38ccb2eb338c23749168a4b9707e9d16 212 SUPERFAMILY SSF89028 26 204 2.35E-57 T 06-07-2017 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 CAK77_RS07305 38ccb2eb338c23749168a4b9707e9d16 212 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 28 199 6.3E-49 T 06-07-2017 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 CAK77_RS07305 38ccb2eb338c23749168a4b9707e9d16 212 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 33 165 2.0E-60 T 06-07-2017 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 CAK77_RS07305 38ccb2eb338c23749168a4b9707e9d16 212 Gene3D G3DSA:1.20.1200.10 36 207 2.0E-57 T 06-07-2017 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 CAK77_RS07305 38ccb2eb338c23749168a4b9707e9d16 212 Pfam PF01923 Cobalamin adenosyltransferase 27 194 2.8E-56 T 06-07-2017 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 CAK77_RS20935 7e4f0551c9f02b432d9e8cd6b77d39c6 391 SUPERFAMILY SSF52540 96 144 1.77E-30 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS20935 7e4f0551c9f02b432d9e8cd6b77d39c6 391 SUPERFAMILY SSF52540 208 356 1.77E-30 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS20935 7e4f0551c9f02b432d9e8cd6b77d39c6 391 Gene3D G3DSA:3.40.50.300 96 156 3.2E-10 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS20935 7e4f0551c9f02b432d9e8cd6b77d39c6 391 Gene3D G3DSA:3.40.50.300 232 356 3.2E-10 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS20935 7e4f0551c9f02b432d9e8cd6b77d39c6 391 Pfam PF13469 Sulfotransferase family 100 347 1.0E-59 T 06-07-2017 CAK77_RS09685 9460586f5b9533e0f741efb3e73417cd 329 Pfam PF00348 Polyprenyl synthetase 10 254 1.7E-48 T 06-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 CAK77_RS09685 9460586f5b9533e0f741efb3e73417cd 329 SUPERFAMILY SSF48576 4 328 4.68E-74 T 06-07-2017 IPR008949 Isoprenoid synthase domain CAK77_RS09685 9460586f5b9533e0f741efb3e73417cd 329 Gene3D G3DSA:1.10.600.10 3 328 6.5E-82 T 06-07-2017 IPR008949 Isoprenoid synthase domain CAK77_RS09685 9460586f5b9533e0f741efb3e73417cd 329 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 61 75 - T 06-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 CAK77_RS09685 9460586f5b9533e0f741efb3e73417cd 329 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 205 217 - T 06-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 CAK77_RS12900 41e238916e9246f539ec8b4b58e538c5 314 Pfam PF00005 ABC transporter 60 220 5.0E-32 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK77_RS12900 41e238916e9246f539ec8b4b58e538c5 314 Gene3D G3DSA:3.40.50.300 42 290 7.3E-71 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS12900 41e238916e9246f539ec8b4b58e538c5 314 SUPERFAMILY SSF52540 43 291 1.59E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS12900 41e238916e9246f539ec8b4b58e538c5 314 SMART SM00382 69 269 8.5E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS12900 41e238916e9246f539ec8b4b58e538c5 314 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 269 291 1.3E-12 T 06-07-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CAK77_RS17255 be2af3faec2e656ca933c1a500df22b5 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 31 44 3.1E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS17255 be2af3faec2e656ca933c1a500df22b5 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 52 75 3.1E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS17255 be2af3faec2e656ca933c1a500df22b5 205 Gene3D G3DSA:1.10.10.60 20 72 2.4E-20 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS17255 be2af3faec2e656ca933c1a500df22b5 205 SUPERFAMILY SSF46689 22 81 3.09E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS17255 be2af3faec2e656ca933c1a500df22b5 205 SUPERFAMILY SSF48498 89 204 1.08E-24 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS17255 be2af3faec2e656ca933c1a500df22b5 205 Gene3D G3DSA:1.10.357.10 73 202 6.1E-38 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS17255 be2af3faec2e656ca933c1a500df22b5 205 Pfam PF00440 Bacterial regulatory proteins, tetR family 32 74 7.2E-13 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS17255 be2af3faec2e656ca933c1a500df22b5 205 Pfam PF16859 Bacterial transcriptional repressor C-terminal 88 199 1.9E-30 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS01645 b3c7809b3d51bc4a4fa0e7d225184ce3 189 Gene3D G3DSA:1.10.10.10 53 116 3.2E-4 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS01645 b3c7809b3d51bc4a4fa0e7d225184ce3 189 SUPERFAMILY SSF46785 53 135 2.72E-6 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS02290 c5373770facaf8965c29442e97e6fdf8 157 Gene3D G3DSA:3.30.1330.40 2 151 8.3E-66 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAK77_RS02290 c5373770facaf8965c29442e97e6fdf8 157 Pfam PF14588 YjgF/chorismate_mutase-like, putative endoribonuclease 6 150 2.4E-32 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAK77_RS02290 c5373770facaf8965c29442e97e6fdf8 157 SUPERFAMILY SSF55298 1 151 7.7E-55 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAK77_RS09390 88138abc437b53d6401ede211b1a8bd4 478 Gene3D G3DSA:3.30.590.10 109 458 1.4E-137 T 06-07-2017 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 CAK77_RS09390 88138abc437b53d6401ede211b1a8bd4 478 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 8 477 2.9E-206 T 06-07-2017 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CAK77_RS09390 88138abc437b53d6401ede211b1a8bd4 478 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 17 98 1.3E-26 T 06-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CAK77_RS09390 88138abc437b53d6401ede211b1a8bd4 478 SUPERFAMILY SSF54368 6 103 1.44E-33 T 06-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CAK77_RS09390 88138abc437b53d6401ede211b1a8bd4 478 Pfam PF00120 Glutamine synthetase, catalytic domain 106 475 1.5E-135 T 06-07-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CAK77_RS09390 88138abc437b53d6401ede211b1a8bd4 478 SUPERFAMILY SSF55931 106 477 3.92E-140 T 06-07-2017 CAK77_RS09390 88138abc437b53d6401ede211b1a8bd4 478 ProSitePatterns PS00182 Glutamine synthetase class-I adenylation site. 394 406 - T 06-07-2017 IPR001637 Glutamine synthetase class-I, adenylation site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CAK77_RS09390 88138abc437b53d6401ede211b1a8bd4 478 SMART SM01230 105 387 1.5E-153 T 06-07-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CAK77_RS09390 88138abc437b53d6401ede211b1a8bd4 478 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 265 280 - T 06-07-2017 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 CAK77_RS09390 88138abc437b53d6401ede211b1a8bd4 478 ProSitePatterns PS00180 Glutamine synthetase signature 1. 53 71 - T 06-07-2017 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 CAK77_RS09390 88138abc437b53d6401ede211b1a8bd4 478 Gene3D G3DSA:3.10.20.70 6 108 2.2E-37 T 06-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CAK77_RS13710 ef7e86a7ab9cd44e6945970b97a424e8 288 SUPERFAMILY SSF53850 31 273 5.79E-64 T 06-07-2017 CAK77_RS13710 ef7e86a7ab9cd44e6945970b97a424e8 288 Pfam PF03180 NLPA lipoprotein 31 264 5.9E-68 T 06-07-2017 IPR004872 Lipoprotein NlpA family CAK77_RS13710 ef7e86a7ab9cd44e6945970b97a424e8 288 Gene3D G3DSA:3.40.190.10 31 156 1.8E-42 T 06-07-2017 CAK77_RS14095 9ed9a011c26cf6ddc7b9fc3987fc7d91 112 PRINTS PR01853 Bacterial YajC preprotein translocase signature 4 24 1.3E-6 T 06-07-2017 IPR003849 Preprotein translocase YajC CAK77_RS14095 9ed9a011c26cf6ddc7b9fc3987fc7d91 112 PRINTS PR01853 Bacterial YajC preprotein translocase signature 42 60 1.3E-6 T 06-07-2017 IPR003849 Preprotein translocase YajC CAK77_RS14095 9ed9a011c26cf6ddc7b9fc3987fc7d91 112 SMART SM01323 2 84 1.5E-26 T 06-07-2017 IPR003849 Preprotein translocase YajC CAK77_RS14095 9ed9a011c26cf6ddc7b9fc3987fc7d91 112 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 5 83 1.6E-23 T 06-07-2017 IPR003849 Preprotein translocase YajC CAK77_RS14095 9ed9a011c26cf6ddc7b9fc3987fc7d91 112 Pfam PF02699 Preprotein translocase subunit 6 81 9.3E-18 T 06-07-2017 IPR003849 Preprotein translocase YajC CAK77_RS18715 9f7986f4fd4299ee3402e252254e4448 147 Gene3D G3DSA:3.90.1180.10 3 141 9.2E-60 T 06-07-2017 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CAK77_RS18715 9f7986f4fd4299ee3402e252254e4448 147 PIRSF PIRSF002181 3 147 1.3E-44 T 06-07-2017 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CAK77_RS18715 9f7986f4fd4299ee3402e252254e4448 147 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 15 139 26.944 T 06-07-2017 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CAK77_RS18715 9f7986f4fd4299ee3402e252254e4448 147 ProSitePatterns PS00783 Ribosomal protein L13 signature. 105 127 - T 06-07-2017 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 CAK77_RS18715 9f7986f4fd4299ee3402e252254e4448 147 Pfam PF00572 Ribosomal protein L13 15 137 3.9E-52 T 06-07-2017 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CAK77_RS18715 9f7986f4fd4299ee3402e252254e4448 147 SUPERFAMILY SSF52161 4 144 2.09E-57 T 06-07-2017 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CAK77_RS18715 9f7986f4fd4299ee3402e252254e4448 147 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 5 141 3.2E-58 T 06-07-2017 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS06185 7df5f9ba344de9713d80786599a12e63 560 Gene3D G3DSA:3.50.50.60 193 299 2.1E-79 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS06185 7df5f9ba344de9713d80786599a12e63 560 Gene3D G3DSA:3.50.50.60 2 125 2.1E-79 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS06185 7df5f9ba344de9713d80786599a12e63 560 Gene3D G3DSA:3.50.50.60 390 403 2.1E-79 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS06185 7df5f9ba344de9713d80786599a12e63 560 Gene3D G3DSA:3.50.50.60 451 518 2.1E-79 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS06185 7df5f9ba344de9713d80786599a12e63 560 SUPERFAMILY SSF51905 1 302 1.99E-44 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS06185 7df5f9ba344de9713d80786599a12e63 560 SUPERFAMILY SSF51905 460 516 1.99E-44 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS06185 7df5f9ba344de9713d80786599a12e63 560 Pfam PF00732 GMC oxidoreductase 5 275 9.1E-10 T 06-07-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CAK77_RS06185 7df5f9ba344de9713d80786599a12e63 560 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 2.7E-6 T 06-07-2017 CAK77_RS06185 7df5f9ba344de9713d80786599a12e63 560 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 527 547 2.7E-6 T 06-07-2017 CAK77_RS06185 7df5f9ba344de9713d80786599a12e63 560 Pfam PF05199 GMC oxidoreductase 454 512 1.2E-14 T 06-07-2017 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 CAK77_RS02455 19a4195e3f4d5d51dee0f54e81219c5c 402 SUPERFAMILY SSF56349 174 384 1.24E-29 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CAK77_RS02455 19a4195e3f4d5d51dee0f54e81219c5c 402 Gene3D G3DSA:1.10.443.10 176 381 9.5E-33 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAK77_RS02455 19a4195e3f4d5d51dee0f54e81219c5c 402 Gene3D G3DSA:1.10.150.130 30 126 1.6E-10 T 06-07-2017 IPR023109 Integrase/recombinase, N-terminal CAK77_RS02455 19a4195e3f4d5d51dee0f54e81219c5c 402 Pfam PF00589 Phage integrase family 175 372 3.0E-23 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAK77_RS02455 19a4195e3f4d5d51dee0f54e81219c5c 402 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 31 123 2.7E-7 T 06-07-2017 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CAK77_RS00135 19a4195e3f4d5d51dee0f54e81219c5c 402 SUPERFAMILY SSF56349 174 384 1.24E-29 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CAK77_RS00135 19a4195e3f4d5d51dee0f54e81219c5c 402 Gene3D G3DSA:1.10.443.10 176 381 9.5E-33 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAK77_RS00135 19a4195e3f4d5d51dee0f54e81219c5c 402 Gene3D G3DSA:1.10.150.130 30 126 1.6E-10 T 06-07-2017 IPR023109 Integrase/recombinase, N-terminal CAK77_RS00135 19a4195e3f4d5d51dee0f54e81219c5c 402 Pfam PF00589 Phage integrase family 175 372 3.0E-23 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAK77_RS00135 19a4195e3f4d5d51dee0f54e81219c5c 402 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 31 123 2.7E-7 T 06-07-2017 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CAK77_RS05260 73ea5fad4333f00f6afa5f25e86b2a06 378 Gene3D G3DSA:3.30.1220.10 246 349 2.0E-16 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CAK77_RS05260 73ea5fad4333f00f6afa5f25e86b2a06 378 Gene3D G3DSA:3.40.50.300 7 231 3.1E-74 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS05260 73ea5fad4333f00f6afa5f25e86b2a06 378 SMART SM00833 258 349 3.6E-30 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CAK77_RS05260 73ea5fad4333f00f6afa5f25e86b2a06 378 SUPERFAMILY SSF52540 7 305 1.5E-41 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS05260 73ea5fad4333f00f6afa5f25e86b2a06 378 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 8 212 3.5E-58 T 06-07-2017 IPR003495 CobW/HypB/UreG, nucleotide-binding domain CAK77_RS05260 73ea5fad4333f00f6afa5f25e86b2a06 378 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 258 348 8.3E-24 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CAK77_RS19585 923659f950e8458570786f12c08c6cc7 37 Pfam PF00589 Phage integrase family 1 30 3.7E-5 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAK77_RS19585 923659f950e8458570786f12c08c6cc7 37 Gene3D G3DSA:1.10.443.10 1 36 1.6E-8 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAK77_RS19585 923659f950e8458570786f12c08c6cc7 37 SUPERFAMILY SSF56349 2 35 1.35E-8 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CAK77_RS15750 f8fa3c42fe62afe206d2694bddf92c86 248 Gene3D G3DSA:2.40.440.10 128 246 2.5E-21 T 06-07-2017 CAK77_RS15750 f8fa3c42fe62afe206d2694bddf92c86 248 Pfam PF03734 L,D-transpeptidase catalytic domain 131 246 2.4E-18 T 06-07-2017 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 CAK77_RS15750 f8fa3c42fe62afe206d2694bddf92c86 248 SUPERFAMILY SSF141523 127 246 3.92E-30 T 06-07-2017 CAK77_RS13920 9af10ab8703a910589358d8aabf7e9d0 239 Gene3D G3DSA:1.10.357.10 12 211 4.7E-22 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS13920 9af10ab8703a910589358d8aabf7e9d0 239 SUPERFAMILY SSF48498 103 211 2.08E-5 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS13920 9af10ab8703a910589358d8aabf7e9d0 239 SUPERFAMILY SSF46689 17 89 2.46E-8 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS13920 9af10ab8703a910589358d8aabf7e9d0 239 Pfam PF00440 Bacterial regulatory proteins, tetR family 48 72 1.3E-4 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS18750 543b9e78213928ab13403c317c1f2b4d 493 TIGRFAM TIGR03919 T7SS_EccB: type VII secretion protein EccB 6 462 1.1E-178 T 06-07-2017 IPR007795 Type VII secretion system EccB CAK77_RS18750 543b9e78213928ab13403c317c1f2b4d 493 Pfam PF05108 Type VII secretion system ESX-1, transport TM domain B 3 475 8.1E-185 T 06-07-2017 IPR007795 Type VII secretion system EccB CAK77_RS22310 5907844d71f5f65708efb89f88076c10 409 Gene3D G3DSA:3.40.50.2000 181 364 4.2E-28 T 06-07-2017 CAK77_RS22310 5907844d71f5f65708efb89f88076c10 409 Pfam PF13439 Glycosyltransferase Family 4 29 193 1.2E-19 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 CAK77_RS22310 5907844d71f5f65708efb89f88076c10 409 Pfam PF00534 Glycosyl transferases group 1 209 365 1.9E-29 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 CAK77_RS22310 5907844d71f5f65708efb89f88076c10 409 SUPERFAMILY SSF53756 15 385 7.18E-69 T 06-07-2017 CAK77_RS00635 8ebc7b8e314ae2210c63d28775d7ae10 88 SUPERFAMILY SSF47413 13 77 1.36E-13 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK77_RS00635 8ebc7b8e314ae2210c63d28775d7ae10 88 Pfam PF13560 Helix-turn-helix domain 16 76 1.2E-11 T 06-07-2017 CAK77_RS00635 8ebc7b8e314ae2210c63d28775d7ae10 88 SMART SM00530 20 74 2.2E-4 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAK77_RS00635 8ebc7b8e314ae2210c63d28775d7ae10 88 Gene3D G3DSA:1.10.260.40 9 75 1.9E-20 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK77_RS02715 b1d006ef1b7028d877afded06995c079 357 Pfam PF10103 Zinicin-like metallopeptidase 26 353 1.5E-105 T 06-07-2017 IPR018766 Zinicin-like metallopeptidase type 2 CAK77_RS02715 b1d006ef1b7028d877afded06995c079 357 TIGRFAM TIGR03883 DUF2342_F420: uncharacterized protein, coenzyme F420 biosynthesis associated 26 356 5.7E-126 T 06-07-2017 IPR022454 Conserved hypothetical protein CHP03883, F420 biosynthesis associated CAK77_RS02715 b1d006ef1b7028d877afded06995c079 357 SUPERFAMILY SSF55486 25 356 2.2E-101 T 06-07-2017 CAK77_RS02715 b1d006ef1b7028d877afded06995c079 357 TIGRFAM TIGR03624 TIGR03624: putative hydrolase 26 356 9.0E-114 T 06-07-2017 IPR018766 Zinicin-like metallopeptidase type 2 CAK77_RS20280 846cafb6b02ec0a50bedfd3420adf2d3 463 SUPERFAMILY SSF47384 145 220 2.55E-14 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK77_RS20280 846cafb6b02ec0a50bedfd3420adf2d3 463 SMART SM00387 267 379 5.0E-38 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS20280 846cafb6b02ec0a50bedfd3420adf2d3 463 SMART SM00388 156 222 2.2E-15 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK77_RS20280 846cafb6b02ec0a50bedfd3420adf2d3 463 Gene3D G3DSA:1.10.287.130 152 208 7.4E-13 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK77_RS20280 846cafb6b02ec0a50bedfd3420adf2d3 463 PRINTS PR00344 Bacterial sensor protein C-terminal signature 363 376 2.8E-20 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK77_RS20280 846cafb6b02ec0a50bedfd3420adf2d3 463 PRINTS PR00344 Bacterial sensor protein C-terminal signature 339 357 2.8E-20 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK77_RS20280 846cafb6b02ec0a50bedfd3420adf2d3 463 PRINTS PR00344 Bacterial sensor protein C-terminal signature 304 318 2.8E-20 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK77_RS20280 846cafb6b02ec0a50bedfd3420adf2d3 463 PRINTS PR00344 Bacterial sensor protein C-terminal signature 322 332 2.8E-20 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAK77_RS20280 846cafb6b02ec0a50bedfd3420adf2d3 463 Pfam PF00512 His Kinase A (phospho-acceptor) domain 157 221 3.9E-12 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAK77_RS20280 846cafb6b02ec0a50bedfd3420adf2d3 463 Gene3D G3DSA:3.30.450.20 49 142 2.6E-4 T 06-07-2017 CAK77_RS20280 846cafb6b02ec0a50bedfd3420adf2d3 463 SUPERFAMILY SSF55874 212 380 1.44E-45 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS20280 846cafb6b02ec0a50bedfd3420adf2d3 463 Gene3D G3DSA:3.30.565.10 209 380 8.5E-46 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS20280 846cafb6b02ec0a50bedfd3420adf2d3 463 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 267 377 6.9E-23 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAK77_RS15015 81c77c07ed679e5b783b46218bb8fbed 276 SUPERFAMILY SSF51679 4 252 2.8E-41 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS15015 81c77c07ed679e5b783b46218bb8fbed 276 Gene3D G3DSA:3.20.20.30 3 226 3.2E-41 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS15015 81c77c07ed679e5b783b46218bb8fbed 276 Pfam PF00296 Luciferase-like monooxygenase 14 224 8.5E-26 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS15015 81c77c07ed679e5b783b46218bb8fbed 276 TIGRFAM TIGR03856 F420_MSMEG_2906: probable F420-dependent oxidoreductase, MSMEG_2906 family 5 273 3.2E-115 T 06-07-2017 IPR022480 F420-dependent oxidoreductase, MSMEG2906 CAK77_RS03750 cbf6e16a10b87a3b44c864cb15e6469d 222 Gene3D G3DSA:1.10.357.10 37 210 6.9E-34 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS03750 cbf6e16a10b87a3b44c864cb15e6469d 222 SUPERFAMILY SSF46689 32 110 1.44E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS03750 cbf6e16a10b87a3b44c864cb15e6469d 222 Pfam PF00440 Bacterial regulatory proteins, tetR family 42 88 1.4E-13 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS03750 cbf6e16a10b87a3b44c864cb15e6469d 222 Pfam PF16925 Bacterial transcriptional repressor C-terminal 110 212 5.7E-22 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS03750 cbf6e16a10b87a3b44c864cb15e6469d 222 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 55 7.3E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS03750 cbf6e16a10b87a3b44c864cb15e6469d 222 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 63 86 7.3E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS03750 cbf6e16a10b87a3b44c864cb15e6469d 222 SUPERFAMILY SSF48498 109 210 2.22E-20 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS21790 24da8532709bf0218eef06fe6abbe53d 199 Gene3D G3DSA:1.10.357.10 14 194 1.3E-22 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS21790 24da8532709bf0218eef06fe6abbe53d 199 SUPERFAMILY SSF46689 14 84 2.82E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS20475 5987ddb3f22a054683d9e32e834cabc4 279 PIRSF PIRSF028756 14 278 3.7E-69 T 06-07-2017 IPR016898 Polyphosphate kinase 2 CAK77_RS20475 5987ddb3f22a054683d9e32e834cabc4 279 Gene3D G3DSA:3.40.50.300 25 276 6.2E-89 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS20475 5987ddb3f22a054683d9e32e834cabc4 279 TIGRFAM TIGR03709 PPK2_rel_1: polyphosphate:nucleotide phosphotransferase, PPK2 family 16 272 8.1E-105 T 06-07-2017 IPR022300 Polyphosphate:nucleotide phosphotransferase, PPK2 GO:0006797|GO:0016776 CAK77_RS20475 5987ddb3f22a054683d9e32e834cabc4 279 SUPERFAMILY SSF52540 67 246 2.13E-16 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS20475 5987ddb3f22a054683d9e32e834cabc4 279 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 33 255 1.4E-63 T 06-07-2017 IPR022488 Polyphosphate kinase-2-related CAK77_RS01515 bb114c2b3470e5a66c7f457478587edf 393 SUPERFAMILY SSF51569 17 392 2.56E-136 T 06-07-2017 CAK77_RS01515 bb114c2b3470e5a66c7f457478587edf 393 Pfam PF01474 Class-II DAHP synthetase family 181 389 4.0E-79 T 06-07-2017 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 CAK77_RS01515 bb114c2b3470e5a66c7f457478587edf 393 Pfam PF01474 Class-II DAHP synthetase family 17 170 4.4E-44 T 06-07-2017 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 CAK77_RS03130 3243e093280cce39e579f8fa3c699724 249 SUPERFAMILY SSF100950 3 245 7.7E-49 T 06-07-2017 CAK77_RS03130 3243e093280cce39e579f8fa3c699724 249 Gene3D G3DSA:3.40.810.20 2 246 1.0E-63 T 06-07-2017 CAK77_RS03130 3243e093280cce39e579f8fa3c699724 249 SMART SM00882 8 208 0.002 T 06-07-2017 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 CAK77_RS14185 a781022d086d61381735b3bbd560653c 354 SUPERFAMILY SSF46689 250 296 5.82E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS14185 a781022d086d61381735b3bbd560653c 354 Pfam PF12833 Helix-turn-helix domain 269 347 4.8E-22 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK77_RS14185 a781022d086d61381735b3bbd560653c 354 Gene3D G3DSA:1.10.10.60 302 350 6.6E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS14185 a781022d086d61381735b3bbd560653c 354 SUPERFAMILY SSF46689 299 350 1.75E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS14185 a781022d086d61381735b3bbd560653c 354 Pfam PF01965 DJ-1/PfpI family 43 209 5.6E-16 T 06-07-2017 IPR002818 DJ-1/PfpI CAK77_RS14185 a781022d086d61381735b3bbd560653c 354 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 300 342 - T 06-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CAK77_RS14185 a781022d086d61381735b3bbd560653c 354 SUPERFAMILY SSF52317 41 230 1.83E-43 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAK77_RS14185 a781022d086d61381735b3bbd560653c 354 Gene3D G3DSA:1.10.10.60 256 301 8.9E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS14185 a781022d086d61381735b3bbd560653c 354 SMART SM00342 263 346 1.7E-27 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK77_RS14185 a781022d086d61381735b3bbd560653c 354 Gene3D G3DSA:3.40.50.880 43 255 5.7E-47 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAK77_RS23370 c5c4f180eef6e53199d7f87a60dfc7fe 467 Pfam PF00067 Cytochrome P450 10 422 6.1E-59 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS23370 c5c4f180eef6e53199d7f87a60dfc7fe 467 Gene3D G3DSA:1.10.630.10 8 439 3.3E-84 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS23370 c5c4f180eef6e53199d7f87a60dfc7fe 467 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 381 390 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CAK77_RS23370 c5c4f180eef6e53199d7f87a60dfc7fe 467 SUPERFAMILY SSF48264 8 422 1.57E-82 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS23370 c5c4f180eef6e53199d7f87a60dfc7fe 467 PRINTS PR00463 E-class P450 group I signature 388 411 6.7E-20 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS23370 c5c4f180eef6e53199d7f87a60dfc7fe 467 PRINTS PR00463 E-class P450 group I signature 378 388 6.7E-20 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS23370 c5c4f180eef6e53199d7f87a60dfc7fe 467 PRINTS PR00463 E-class P450 group I signature 306 324 6.7E-20 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS23370 c5c4f180eef6e53199d7f87a60dfc7fe 467 PRINTS PR00463 E-class P450 group I signature 250 267 6.7E-20 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS23370 c5c4f180eef6e53199d7f87a60dfc7fe 467 PRINTS PR00463 E-class P450 group I signature 346 370 6.7E-20 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS23370 c5c4f180eef6e53199d7f87a60dfc7fe 467 PRINTS PR00463 E-class P450 group I signature 36 55 6.7E-20 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS23370 c5c4f180eef6e53199d7f87a60dfc7fe 467 PRINTS PR00463 E-class P450 group I signature 270 296 6.7E-20 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS23370 c5c4f180eef6e53199d7f87a60dfc7fe 467 PRINTS PR00385 P450 superfamily signature 388 399 6.7E-15 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS23370 c5c4f180eef6e53199d7f87a60dfc7fe 467 PRINTS PR00385 P450 superfamily signature 307 318 6.7E-15 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS23370 c5c4f180eef6e53199d7f87a60dfc7fe 467 PRINTS PR00385 P450 superfamily signature 379 388 6.7E-15 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS23370 c5c4f180eef6e53199d7f87a60dfc7fe 467 PRINTS PR00385 P450 superfamily signature 261 278 6.7E-15 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS01795 0bac4235bea23bb8d17a9893d9ad25ac 441 Gene3D G3DSA:1.10.3430.10 8 406 9.2E-129 T 06-07-2017 IPR029020 Ammonium/urea transporter CAK77_RS01795 0bac4235bea23bb8d17a9893d9ad25ac 441 PRINTS PR00342 Rhesus blood group protein signature 16 34 7.6E-6 T 06-07-2017 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 CAK77_RS01795 0bac4235bea23bb8d17a9893d9ad25ac 441 PRINTS PR00342 Rhesus blood group protein signature 118 134 7.6E-6 T 06-07-2017 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 CAK77_RS01795 0bac4235bea23bb8d17a9893d9ad25ac 441 PRINTS PR00342 Rhesus blood group protein signature 221 239 7.6E-6 T 06-07-2017 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 CAK77_RS01795 0bac4235bea23bb8d17a9893d9ad25ac 441 PRINTS PR00342 Rhesus blood group protein signature 285 298 7.6E-6 T 06-07-2017 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 CAK77_RS01795 0bac4235bea23bb8d17a9893d9ad25ac 441 TIGRFAM TIGR00836 amt: ammonium transporter 12 426 1.9E-130 T 06-07-2017 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 CAK77_RS01795 0bac4235bea23bb8d17a9893d9ad25ac 441 SUPERFAMILY SSF111352 9 406 1.44E-115 T 06-07-2017 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 CAK77_RS01795 0bac4235bea23bb8d17a9893d9ad25ac 441 Pfam PF00909 Ammonium Transporter Family 14 426 6.2E-122 T 06-07-2017 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 CAK77_RS01795 0bac4235bea23bb8d17a9893d9ad25ac 441 ProSitePatterns PS01219 Ammonium transporters signature. 182 207 - T 06-07-2017 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 CAK77_RS05245 79bea3efdf8c174680f5797b315cc369 144 SUPERFAMILY SSF50475 8 131 7.85E-26 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS05245 79bea3efdf8c174680f5797b315cc369 144 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 14 130 3.7E-23 T 06-07-2017 IPR024747 Pyridoxamine 5'-phosphate oxidase-related CAK77_RS05245 79bea3efdf8c174680f5797b315cc369 144 Gene3D G3DSA:2.30.110.10 2 137 5.7E-44 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS05440 5f69b1c1bf530908b68001d2b33bc024 131 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 4 18 1.4E-7 T 06-07-2017 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CAK77_RS05440 5f69b1c1bf530908b68001d2b33bc024 131 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 88 97 1.4E-7 T 06-07-2017 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CAK77_RS05440 5f69b1c1bf530908b68001d2b33bc024 131 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 78 86 1.4E-7 T 06-07-2017 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CAK77_RS05440 5f69b1c1bf530908b68001d2b33bc024 131 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 1 127 1.1E-24 T 06-07-2017 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CAK77_RS05440 5f69b1c1bf530908b68001d2b33bc024 131 ProSitePatterns PS01327 Large-conductance mechanosensitive channels mscL family signature. 11 24 - T 06-07-2017 IPR019823 Large-conductance mechanosensitive channel, conserved site CAK77_RS05440 5f69b1c1bf530908b68001d2b33bc024 131 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 1 124 1.6E-34 T 06-07-2017 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CAK77_RS05440 5f69b1c1bf530908b68001d2b33bc024 131 SUPERFAMILY SSF81330 10 121 6.93E-27 T 06-07-2017 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CAK77_RS11500 ee4eac34e8a7486b941d6d796aa81f15 398 SUPERFAMILY SSF63999 183 306 1.44E-9 T 06-07-2017 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CAK77_RS11500 ee4eac34e8a7486b941d6d796aa81f15 398 Pfam PF12555 Thiamine pyrophosphokinase C terminal 339 389 4.1E-17 T 06-07-2017 IPR022215 Thiamine pyrophosphokinase C-terminal CAK77_RS09405 65bf44c18b28e26122014f1d227d0fc8 278 Pfam PF13444 Acetyltransferase (GNAT) domain 44 151 1.7E-22 T 06-07-2017 CAK77_RS09405 65bf44c18b28e26122014f1d227d0fc8 278 Gene3D G3DSA:3.40.630.30 33 174 1.8E-25 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS09405 65bf44c18b28e26122014f1d227d0fc8 278 SUPERFAMILY SSF55729 26 247 1.04E-32 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS12605 22e97125d0452eb024a64c28ece4aaa0 636 Pfam PF07693 KAP family P-loop domain 26 368 3.2E-41 T 06-07-2017 IPR011646 KAP family P-loop domain CAK77_RS12605 22e97125d0452eb024a64c28ece4aaa0 636 SUPERFAMILY SSF52540 328 377 1.11E-9 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS12605 22e97125d0452eb024a64c28ece4aaa0 636 SUPERFAMILY SSF52540 165 287 1.11E-9 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS12605 22e97125d0452eb024a64c28ece4aaa0 636 SUPERFAMILY SSF52540 40 131 1.11E-9 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS12605 22e97125d0452eb024a64c28ece4aaa0 636 Gene3D G3DSA:3.40.50.300 58 100 1.6E-4 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS12605 22e97125d0452eb024a64c28ece4aaa0 636 Gene3D G3DSA:3.40.50.300 141 206 8.1E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS12605 22e97125d0452eb024a64c28ece4aaa0 636 Gene3D G3DSA:3.40.50.300 40 57 8.1E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS05570 a2581fbb33a7c9136fbd81a421266c4a 417 SUPERFAMILY SSF56322 38 406 1.06E-90 T 06-07-2017 IPR005801 ADC synthase GO:0009058 CAK77_RS05570 a2581fbb33a7c9136fbd81a421266c4a 417 Pfam PF00425 chorismate binding enzyme 153 400 3.7E-69 T 06-07-2017 IPR015890 Chorismate-utilising enzyme, C-terminal CAK77_RS05570 a2581fbb33a7c9136fbd81a421266c4a 417 Gene3D G3DSA:3.60.120.10 74 407 4.6E-98 T 06-07-2017 IPR005801 ADC synthase GO:0009058 CAK77_RS05570 a2581fbb33a7c9136fbd81a421266c4a 417 PRINTS PR00095 Anthranilate synthase component I signature 261 274 1.7E-11 T 06-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CAK77_RS05570 a2581fbb33a7c9136fbd81a421266c4a 417 PRINTS PR00095 Anthranilate synthase component I signature 356 370 1.7E-11 T 06-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CAK77_RS05570 a2581fbb33a7c9136fbd81a421266c4a 417 PRINTS PR00095 Anthranilate synthase component I signature 247 260 1.7E-11 T 06-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CAK77_RS05570 a2581fbb33a7c9136fbd81a421266c4a 417 PRINTS PR00095 Anthranilate synthase component I signature 341 355 1.7E-11 T 06-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CAK77_RS05570 a2581fbb33a7c9136fbd81a421266c4a 417 TIGRFAM TIGR00553 pabB: aminodeoxychorismate synthase, component I 79 402 1.3E-102 T 06-07-2017 IPR005802 Para-aminobenzoate synthase, component I GO:0009396 KEGG: 00790+2.6.1.85|MetaCyc: PWY-6543 CAK77_RS00275 ccc540786ca2fd3fcaba05a846ad6d56 411 SUPERFAMILY SSF103473 16 400 1.83E-47 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK77_RS00275 ccc540786ca2fd3fcaba05a846ad6d56 411 Gene3D G3DSA:1.20.1250.20 226 401 4.4E-11 T 06-07-2017 CAK77_RS00275 ccc540786ca2fd3fcaba05a846ad6d56 411 Gene3D G3DSA:1.20.1250.20 19 194 6.0E-20 T 06-07-2017 CAK77_RS00275 ccc540786ca2fd3fcaba05a846ad6d56 411 Pfam PF07690 Major Facilitator Superfamily 25 333 6.3E-27 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK77_RS20655 57584bfd9017912f04063ce9b609ca9f 139 SUPERFAMILY SSF46955 11 124 2.89E-26 T 06-07-2017 IPR009061 Putative DNA-binding domain CAK77_RS20655 57584bfd9017912f04063ce9b609ca9f 139 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 47 67 5.9E-7 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAK77_RS20655 57584bfd9017912f04063ce9b609ca9f 139 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 12 23 5.9E-7 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAK77_RS20655 57584bfd9017912f04063ce9b609ca9f 139 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 23 36 5.9E-7 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAK77_RS20655 57584bfd9017912f04063ce9b609ca9f 139 Pfam PF13411 MerR HTH family regulatory protein 12 76 3.2E-14 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAK77_RS20655 57584bfd9017912f04063ce9b609ca9f 139 Gene3D G3DSA:1.10.1660.10 12 124 5.7E-28 T 06-07-2017 CAK77_RS20655 57584bfd9017912f04063ce9b609ca9f 139 SMART SM00422 11 80 2.3E-19 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAK77_RS07690 e96f07fdbab720fa6bb051b54094bc00 482 Gene3D G3DSA:3.50.50.60 274 478 1.2E-18 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS07690 e96f07fdbab720fa6bb051b54094bc00 482 Gene3D G3DSA:3.50.50.60 4 208 3.7E-63 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS07690 e96f07fdbab720fa6bb051b54094bc00 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 172 197 8.4E-6 T 06-07-2017 CAK77_RS07690 e96f07fdbab720fa6bb051b54094bc00 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 8 30 8.4E-6 T 06-07-2017 CAK77_RS07690 e96f07fdbab720fa6bb051b54094bc00 482 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 10 206 2.8E-20 T 06-07-2017 CAK77_RS07690 e96f07fdbab720fa6bb051b54094bc00 482 SUPERFAMILY SSF51905 292 409 2.41E-58 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS07690 e96f07fdbab720fa6bb051b54094bc00 482 SUPERFAMILY SSF51905 7 227 2.41E-58 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS01725 ffd4beb712ccee8ec538cd7b689125ef 200 SUPERFAMILY SSF55469 10 197 7.85E-35 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CAK77_RS01725 ffd4beb712ccee8ec538cd7b689125ef 200 Pfam PF00881 Nitroreductase family 19 93 1.8E-9 T 06-07-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 CAK77_RS01725 ffd4beb712ccee8ec538cd7b689125ef 200 Pfam PF00881 Nitroreductase family 94 159 2.5E-7 T 06-07-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 CAK77_RS01725 ffd4beb712ccee8ec538cd7b689125ef 200 Gene3D G3DSA:3.40.109.10 14 196 2.4E-35 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CAK77_RS18100 1a6817549f607acf92861d0c12cda68f 420 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 39 146 1.9E-10 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS18100 1a6817549f607acf92861d0c12cda68f 420 Gene3D G3DSA:1.20.140.10 249 411 7.3E-49 T 06-07-2017 CAK77_RS18100 1a6817549f607acf92861d0c12cda68f 420 Gene3D G3DSA:2.40.110.10 150 248 2.4E-34 T 06-07-2017 CAK77_RS18100 1a6817549f607acf92861d0c12cda68f 420 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 151 246 9.2E-21 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAK77_RS18100 1a6817549f607acf92861d0c12cda68f 420 Gene3D G3DSA:1.10.540.10 3 148 1.8E-22 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS18100 1a6817549f607acf92861d0c12cda68f 420 SUPERFAMILY SSF56645 22 269 2.49E-60 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK77_RS18100 1a6817549f607acf92861d0c12cda68f 420 SUPERFAMILY SSF47203 256 412 4.51E-45 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS18100 1a6817549f607acf92861d0c12cda68f 420 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 258 405 1.5E-43 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS07860 73f78ea76ccf07e5793c2879f0a9d4bf 546 Gene3D G3DSA:3.90.1300.10 25 401 4.1E-92 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAK77_RS07860 73f78ea76ccf07e5793c2879f0a9d4bf 546 SUPERFAMILY SSF75304 14 406 3.92E-93 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAK77_RS07860 73f78ea76ccf07e5793c2879f0a9d4bf 546 Pfam PF01425 Amidase 28 393 3.8E-72 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAK77_RS07860 73f78ea76ccf07e5793c2879f0a9d4bf 546 TIGRFAM TIGR02713 allophanate_hyd: allophanate hydrolase 13 539 1.9E-187 T 06-07-2017 IPR014085 Allophanate hydrolase KEGG: 00220+3.5.1.54|KEGG: 00791+3.5.1.54|MetaCyc: PWY-5169|MetaCyc: PWY-5703 CAK77_RS13905 4af8f91fc546aa4733d1d2a37703b507 412 PIRSF PIRSF001456 1 384 1.0E-123 T 06-07-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CAK77_RS13905 4af8f91fc546aa4733d1d2a37703b507 412 ProSitePatterns PS00788 Chorismate synthase signature 2. 134 150 - T 06-07-2017 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CAK77_RS13905 4af8f91fc546aa4733d1d2a37703b507 412 SUPERFAMILY SSF103263 2 389 2.35E-134 T 06-07-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CAK77_RS13905 4af8f91fc546aa4733d1d2a37703b507 412 ProSitePatterns PS00787 Chorismate synthase signature 1. 8 23 - T 06-07-2017 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CAK77_RS13905 4af8f91fc546aa4733d1d2a37703b507 412 Hamap MF_00300 Chorismate synthase [aroC]. 2 374 34.431 T 06-07-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CAK77_RS13905 4af8f91fc546aa4733d1d2a37703b507 412 Gene3D G3DSA:3.60.150.10 2 398 2.5E-155 T 06-07-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CAK77_RS13905 4af8f91fc546aa4733d1d2a37703b507 412 Pfam PF01264 Chorismate synthase 2 367 1.1E-117 T 06-07-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CAK77_RS13905 4af8f91fc546aa4733d1d2a37703b507 412 ProSitePatterns PS00789 Chorismate synthase signature 3. 341 357 - T 06-07-2017 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CAK77_RS13905 4af8f91fc546aa4733d1d2a37703b507 412 TIGRFAM TIGR00033 aroC: chorismate synthase 2 372 2.0E-124 T 06-07-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CAK77_RS10730 3144a8ea1167a936763accb57be047f8 130 TIGRFAM TIGR03666 Rv2061_F420: PPOX class probable F420-dependent enzyme, Rv2061 family 7 129 1.3E-45 T 06-07-2017 IPR019965 PPOX class F420-dependent enzyme, family Rv2061, putative CAK77_RS10730 3144a8ea1167a936763accb57be047f8 130 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 15 90 2.2E-11 T 06-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAK77_RS10730 3144a8ea1167a936763accb57be047f8 130 Gene3D G3DSA:2.30.110.10 15 104 9.5E-17 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS10730 3144a8ea1167a936763accb57be047f8 130 SUPERFAMILY SSF50475 16 111 2.99E-19 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS23245 5c019631a209ea589d16fead5c658f71 101 Pfam PF00550 Phosphopantetheine attachment site 29 87 3.1E-8 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS23245 5c019631a209ea589d16fead5c658f71 101 SUPERFAMILY SSF47336 30 94 2.22E-10 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS23245 5c019631a209ea589d16fead5c658f71 101 Gene3D G3DSA:1.10.1200.10 29 94 5.4E-11 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS22200 4ad0582fe0c19af5b819aea50bbe0f18 246 SUPERFAMILY SSF46955 3 83 3.66E-12 T 06-07-2017 IPR009061 Putative DNA-binding domain CAK77_RS22200 4ad0582fe0c19af5b819aea50bbe0f18 246 Gene3D G3DSA:1.10.1660.10 3 86 1.8E-14 T 06-07-2017 CAK77_RS22200 4ad0582fe0c19af5b819aea50bbe0f18 246 Pfam PF13411 MerR HTH family regulatory protein 4 70 1.3E-15 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAK77_RS22200 4ad0582fe0c19af5b819aea50bbe0f18 246 SMART SM00422 3 71 1.5E-10 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAK77_RS00300 714dd7d2a301f4c1391497fc31b9794f 299 Pfam PF04072 Leucine carboxyl methyltransferase 19 199 3.4E-58 T 06-07-2017 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 CAK77_RS00300 714dd7d2a301f4c1391497fc31b9794f 299 Gene3D G3DSA:3.40.50.150 23 213 1.9E-19 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS00300 714dd7d2a301f4c1391497fc31b9794f 299 SUPERFAMILY SSF53335 15 289 1.49E-72 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS00300 714dd7d2a301f4c1391497fc31b9794f 299 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 18 277 3.6E-85 T 06-07-2017 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 CAK77_RS08625 4a6179c2ee1d381bbce2412137448b6a 560 Pfam PF00501 AMP-binding enzyme 44 452 1.6E-61 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK77_RS08625 4a6179c2ee1d381bbce2412137448b6a 560 SUPERFAMILY SSF56801 45 554 9.42E-89 T 06-07-2017 CAK77_RS08625 4a6179c2ee1d381bbce2412137448b6a 560 Gene3D G3DSA:3.40.50.980 184 344 4.1E-30 T 06-07-2017 CAK77_RS08625 4a6179c2ee1d381bbce2412137448b6a 560 Gene3D G3DSA:2.30.38.10 373 445 5.6E-18 T 06-07-2017 CAK77_RS08625 4a6179c2ee1d381bbce2412137448b6a 560 ProSitePatterns PS00455 Putative AMP-binding domain signature. 175 186 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK77_RS08625 4a6179c2ee1d381bbce2412137448b6a 560 Gene3D G3DSA:3.40.50.980 47 183 2.1E-15 T 06-07-2017 CAK77_RS08625 4a6179c2ee1d381bbce2412137448b6a 560 Gene3D G3DSA:3.30.300.30 446 551 1.2E-15 T 06-07-2017 CAK77_RS13335 739969fc35095c9f83bcf0b607f13127 269 Gene3D G3DSA:3.40.50.720 4 265 6.6E-54 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS13335 739969fc35095c9f83bcf0b607f13127 269 PIRSF PIRSF000094 2 269 1.2E-100 T 06-07-2017 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 CAK77_RS13335 739969fc35095c9f83bcf0b607f13127 269 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 265 3.0E-53 T 06-07-2017 CAK77_RS13335 739969fc35095c9f83bcf0b607f13127 269 SUPERFAMILY SSF51735 4 265 6.72E-46 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS02670 f6474a664f84ab5658c460c1a4cf2ff0 321 Pfam PF03741 Integral membrane protein TerC family 70 271 2.2E-51 T 06-07-2017 IPR005496 Integral membrane protein TerC GO:0016021 CAK77_RS02670 f6474a664f84ab5658c460c1a4cf2ff0 321 TIGRFAM TIGR03718 R_switched_Alx: integral membrane protein, TerC family 5 317 1.3E-114 T 06-07-2017 IPR022369 Integral membrane protein TerC, riboswitch-linked GO:0016021 CAK77_RS01180 eeeb976f7175952b717331d34b44f0e1 263 SUPERFAMILY SSF52540 46 242 1.36E-40 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS01180 eeeb976f7175952b717331d34b44f0e1 263 SMART SM00382 57 246 4.7E-6 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS01180 eeeb976f7175952b717331d34b44f0e1 263 Pfam PF00005 ABC transporter 48 178 1.3E-18 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK77_RS01180 eeeb976f7175952b717331d34b44f0e1 263 Gene3D G3DSA:3.40.50.300 46 243 1.2E-39 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS03595 07f406253f6049695b0566b7caab0e85 234 Gene3D G3DSA:3.20.20.370 58 145 7.9E-5 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAK77_RS03595 07f406253f6049695b0566b7caab0e85 234 Pfam PF10096 Uncharacterized protein conserved in bacteria (DUF2334) 13 135 4.7E-18 T 06-07-2017 IPR018763 Protein of unknown function DUF2334 CAK77_RS03595 07f406253f6049695b0566b7caab0e85 234 SUPERFAMILY SSF88713 24 136 1.47E-7 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CAK77_RS20100 0f9a0370ffe607a5c2219bd3deaebe29 419 PRINTS PR01217 Proline rich extensin signature 60 76 1.0E-10 T 06-07-2017 CAK77_RS20100 0f9a0370ffe607a5c2219bd3deaebe29 419 PRINTS PR01217 Proline rich extensin signature 134 150 1.0E-10 T 06-07-2017 CAK77_RS20100 0f9a0370ffe607a5c2219bd3deaebe29 419 PRINTS PR01217 Proline rich extensin signature 163 180 1.0E-10 T 06-07-2017 CAK77_RS20100 0f9a0370ffe607a5c2219bd3deaebe29 419 PRINTS PR01217 Proline rich extensin signature 185 210 1.0E-10 T 06-07-2017 CAK77_RS23840 acfd06133c60c237051ffa2ef5560967 254 Pfam PF07681 DoxX 1 88 2.6E-9 T 06-07-2017 IPR032808 DoxX family CAK77_RS19985 f0ddfb33ba571407678906273f148e07 327 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 124 138 2.4E-57 T 06-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAK77_RS19985 f0ddfb33ba571407678906273f148e07 327 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 244 260 2.4E-57 T 06-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAK77_RS19985 f0ddfb33ba571407678906273f148e07 327 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 193 212 2.4E-57 T 06-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAK77_RS19985 f0ddfb33ba571407678906273f148e07 327 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 269 284 2.4E-57 T 06-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAK77_RS19985 f0ddfb33ba571407678906273f148e07 327 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 155 174 2.4E-57 T 06-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAK77_RS19985 f0ddfb33ba571407678906273f148e07 327 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 299 318 2.4E-57 T 06-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAK77_RS19985 f0ddfb33ba571407678906273f148e07 327 Pfam PF00490 Delta-aminolevulinic acid dehydratase 6 324 1.7E-133 T 06-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAK77_RS19985 f0ddfb33ba571407678906273f148e07 327 Gene3D G3DSA:3.20.20.70 3 326 7.9E-139 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK77_RS19985 f0ddfb33ba571407678906273f148e07 327 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 244 256 - T 06-07-2017 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAK77_RS19985 f0ddfb33ba571407678906273f148e07 327 SUPERFAMILY SSF51569 3 326 9.23E-127 T 06-07-2017 CAK77_RS19985 f0ddfb33ba571407678906273f148e07 327 SMART SM01004 3 325 2.3E-204 T 06-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAK77_RS19985 f0ddfb33ba571407678906273f148e07 327 PIRSF PIRSF001415 1 327 5.1E-139 T 06-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAK77_RS16495 f741b28f7ddb224dc5e5fa15775fc0e9 321 Gene3D G3DSA:1.10.10.10 247 307 5.8E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS16495 f741b28f7ddb224dc5e5fa15775fc0e9 321 SUPERFAMILY SSF46785 245 307 2.61E-9 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS16495 f741b28f7ddb224dc5e5fa15775fc0e9 321 Pfam PF12840 Helix-turn-helix domain 248 302 3.6E-8 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS16495 f741b28f7ddb224dc5e5fa15775fc0e9 321 SMART SM00418 245 321 0.0011 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK77_RS20565 fb8c120f5993372fc33c71419dc7af31 267 SUPERFAMILY SSF53335 74 266 2.26E-38 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS20565 fb8c120f5993372fc33c71419dc7af31 267 Gene3D G3DSA:3.40.50.150 75 225 2.3E-34 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS20565 fb8c120f5993372fc33c71419dc7af31 267 Pfam PF08241 Methyltransferase domain 83 176 1.9E-22 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CAK77_RS06205 6e47d0d0832cd1c4a0e6ee499428eacf 485 Gene3D G3DSA:3.40.640.10 59 133 2.3E-86 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK77_RS06205 6e47d0d0832cd1c4a0e6ee499428eacf 485 Gene3D G3DSA:3.40.640.10 165 338 2.3E-86 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK77_RS06205 6e47d0d0832cd1c4a0e6ee499428eacf 485 Pfam PF00464 Serine hydroxymethyltransferase 31 134 9.1E-27 T 06-07-2017 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CAK77_RS06205 6e47d0d0832cd1c4a0e6ee499428eacf 485 Pfam PF00464 Serine hydroxymethyltransferase 167 438 1.2E-94 T 06-07-2017 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CAK77_RS06205 6e47d0d0832cd1c4a0e6ee499428eacf 485 PIRSF PIRSF000412 10 483 1.8E-155 T 06-07-2017 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CAK77_RS06205 6e47d0d0832cd1c4a0e6ee499428eacf 485 SUPERFAMILY SSF53383 166 468 3.24E-140 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK77_RS06205 6e47d0d0832cd1c4a0e6ee499428eacf 485 SUPERFAMILY SSF53383 21 134 3.24E-140 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK77_RS06205 6e47d0d0832cd1c4a0e6ee499428eacf 485 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 278 294 - T 06-07-2017 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0004372|GO:0006544|GO:0006563|GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CAK77_RS06205 6e47d0d0832cd1c4a0e6ee499428eacf 485 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 29 481 44.206 T 06-07-2017 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CAK77_RS06205 6e47d0d0832cd1c4a0e6ee499428eacf 485 Gene3D G3DSA:3.90.1150.10 339 481 7.1E-46 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK77_RS03590 69094ff200a3087fa4545db75cac82b5 162 ProSitePatterns PS00460 Glutathione peroxidases active site. 24 39 - T 06-07-2017 IPR029759 Glutathione peroxidase active site Reactome: R-HSA-3299685 CAK77_RS03590 69094ff200a3087fa4545db75cac82b5 162 SUPERFAMILY SSF52833 6 161 5.95E-51 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK77_RS03590 69094ff200a3087fa4545db75cac82b5 162 Gene3D G3DSA:3.40.30.10 7 161 4.8E-58 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK77_RS03590 69094ff200a3087fa4545db75cac82b5 162 PIRSF PIRSF000303 1 162 9.5E-59 T 06-07-2017 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CAK77_RS03590 69094ff200a3087fa4545db75cac82b5 162 PRINTS PR01011 Glutathione peroxidase family signature 57 73 2.4E-16 T 06-07-2017 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CAK77_RS03590 69094ff200a3087fa4545db75cac82b5 162 PRINTS PR01011 Glutathione peroxidase family signature 123 132 2.4E-16 T 06-07-2017 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CAK77_RS03590 69094ff200a3087fa4545db75cac82b5 162 PRINTS PR01011 Glutathione peroxidase family signature 22 39 2.4E-16 T 06-07-2017 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CAK77_RS03590 69094ff200a3087fa4545db75cac82b5 162 Pfam PF00255 Glutathione peroxidase 10 110 3.6E-36 T 06-07-2017 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CAK77_RS17565 4f842e86ed41123ed887e9d03cb003fa 449 Pfam PF03109 ABC1 family 113 227 2.2E-34 T 06-07-2017 IPR004147 UbiB domain CAK77_RS17565 4f842e86ed41123ed887e9d03cb003fa 449 Pfam PF01636 Phosphotransferase enzyme family 246 303 2.1E-6 T 06-07-2017 IPR002575 Aminoglycoside phosphotransferase CAK77_RS17565 4f842e86ed41123ed887e9d03cb003fa 449 SUPERFAMILY SSF56112 195 375 3.05E-25 T 06-07-2017 IPR011009 Protein kinase-like domain CAK77_RS17565 4f842e86ed41123ed887e9d03cb003fa 449 SUPERFAMILY SSF56112 95 158 3.05E-25 T 06-07-2017 IPR011009 Protein kinase-like domain CAK77_RS17565 4f842e86ed41123ed887e9d03cb003fa 449 Gene3D G3DSA:3.90.1200.10 35 83 3.6E-7 T 06-07-2017 CAK77_RS17565 4f842e86ed41123ed887e9d03cb003fa 449 Gene3D G3DSA:3.90.1200.10 193 304 3.6E-7 T 06-07-2017 CAK77_RS17565 4f842e86ed41123ed887e9d03cb003fa 449 Gene3D G3DSA:3.30.200.20 132 163 6.0E-4 T 06-07-2017 CAK77_RS15855 ffe27a47a8fd4f5dee586b8255986955 292 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 249 275 - T 06-07-2017 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981 CAK77_RS15855 ffe27a47a8fd4f5dee586b8255986955 292 Pfam PF01148 Cytidylyltransferase family 34 291 1.4E-59 T 06-07-2017 CAK77_RS10180 15e3017fb3cb730f0dfc2b566434b79a 155 Gene3D G3DSA:3.90.79.10 4 148 1.3E-36 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAK77_RS10180 15e3017fb3cb730f0dfc2b566434b79a 155 SUPERFAMILY SSF55811 6 149 3.11E-36 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAK77_RS10180 15e3017fb3cb730f0dfc2b566434b79a 155 ProSitePatterns PS00893 Nudix box signature. 48 69 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CAK77_RS10180 15e3017fb3cb730f0dfc2b566434b79a 155 Pfam PF00293 NUDIX domain 19 135 2.8E-20 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 CAK77_RS10180 15e3017fb3cb730f0dfc2b566434b79a 155 PRINTS PR00502 NUDIX hydrolase family signature 43 57 2.7E-6 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CAK77_RS10180 15e3017fb3cb730f0dfc2b566434b79a 155 PRINTS PR00502 NUDIX hydrolase family signature 57 72 2.7E-6 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CAK77_RS03945 9e504d673915694a1f19a0400356ac2e 218 SUPERFAMILY SSF56959 41 210 9.15E-13 T 06-07-2017 IPR016183 Leukocidin/porin GO:0005576|GO:0051715 CAK77_RS03945 9e504d673915694a1f19a0400356ac2e 218 Gene3D G3DSA:2.60.40.1650 41 106 2.0E-26 T 06-07-2017 CAK77_RS03945 9e504d673915694a1f19a0400356ac2e 218 Gene3D G3DSA:2.60.40.1650 155 217 2.0E-26 T 06-07-2017 CAK77_RS03945 9e504d673915694a1f19a0400356ac2e 218 Pfam PF09203 MspA 47 216 4.5E-44 T 06-07-2017 IPR015286 Porin family, mycobacterial-type CAK77_RS09890 dbef824a3f3e3882682502bd8b3a56a5 959 SUPERFAMILY SSF82866 158 358 1.96E-25 T 06-07-2017 CAK77_RS09890 dbef824a3f3e3882682502bd8b3a56a5 959 Gene3D G3DSA:1.20.1640.10 156 363 5.1E-27 T 06-07-2017 CAK77_RS09890 dbef824a3f3e3882682502bd8b3a56a5 959 Gene3D G3DSA:1.20.1640.10 741 938 4.5E-22 T 06-07-2017 CAK77_RS09890 dbef824a3f3e3882682502bd8b3a56a5 959 Pfam PF03176 MMPL family 614 945 1.1E-83 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 CAK77_RS09890 dbef824a3f3e3882682502bd8b3a56a5 959 Pfam PF03176 MMPL family 58 390 1.7E-97 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 CAK77_RS09890 dbef824a3f3e3882682502bd8b3a56a5 959 SUPERFAMILY SSF82866 712 937 2.49E-26 T 06-07-2017 CAK77_RS09890 dbef824a3f3e3882682502bd8b3a56a5 959 TIGRFAM TIGR00833 actII: transport protein 24 937 3.2E-274 T 06-07-2017 IPR004707 Membrane transport protein MmpL family GO:0016021 CAK77_RS10735 3e9ae2ce9c8aa3f2e273828a72df7f18 170 Pfam PF04186 FxsA cytoplasmic membrane protein 5 106 1.9E-23 T 06-07-2017 IPR007313 FxsA cytoplasmic membrane protein GO:0016020 CAK77_RS16235 f29dc4756b6640862072dc4944e73601 299 Pfam PF14062 Domain of unknown function (DUF4253) 193 299 2.1E-33 T 06-07-2017 IPR025349 Domain of unknown function DUF4253 CAK77_RS20670 ff7e09e3cfb1332b1afc669adb859071 422 Gene3D G3DSA:2.40.110.10 133 214 4.8E-17 T 06-07-2017 CAK77_RS20670 ff7e09e3cfb1332b1afc669adb859071 422 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 25 117 1.0E-4 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS20670 ff7e09e3cfb1332b1afc669adb859071 422 SUPERFAMILY SSF56645 26 223 1.31E-32 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK77_RS20670 ff7e09e3cfb1332b1afc669adb859071 422 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 247 382 2.3E-15 T 06-07-2017 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain CAK77_RS20670 ff7e09e3cfb1332b1afc669adb859071 422 Gene3D G3DSA:1.10.540.10 18 118 1.0E-19 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS20670 ff7e09e3cfb1332b1afc669adb859071 422 SUPERFAMILY SSF47203 245 395 9.34E-16 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS20670 ff7e09e3cfb1332b1afc669adb859071 422 Gene3D G3DSA:1.20.140.10 215 402 1.0E-45 T 06-07-2017 CAK77_RS20670 ff7e09e3cfb1332b1afc669adb859071 422 PIRSF PIRSF016578 2 403 7.1E-31 T 06-07-2017 CAK77_RS06625 ef7284cd04a083c7783ba2d4fc079553 212 Gene3D G3DSA:2.60.40.1650 34 100 9.0E-24 T 06-07-2017 CAK77_RS06625 ef7284cd04a083c7783ba2d4fc079553 212 Gene3D G3DSA:2.60.40.1650 149 211 9.0E-24 T 06-07-2017 CAK77_RS06625 ef7284cd04a083c7783ba2d4fc079553 212 Pfam PF09203 MspA 41 210 4.9E-47 T 06-07-2017 IPR015286 Porin family, mycobacterial-type CAK77_RS06625 ef7284cd04a083c7783ba2d4fc079553 212 SUPERFAMILY SSF56959 37 202 1.9E-11 T 06-07-2017 IPR016183 Leukocidin/porin GO:0005576|GO:0051715 CAK77_RS19250 78a856021cabf50b01fab9f547e99ccd 258 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 101 121 - T 06-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CAK77_RS19250 78a856021cabf50b01fab9f547e99ccd 258 Pfam PF00378 Enoyl-CoA hydratase/isomerase 16 235 3.0E-40 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAK77_RS19250 78a856021cabf50b01fab9f547e99ccd 258 SUPERFAMILY SSF52096 8 231 5.16E-66 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS19250 78a856021cabf50b01fab9f547e99ccd 258 Gene3D G3DSA:3.90.226.10 7 248 1.3E-69 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS19825 acd57cc1abd73005a506ef8fea8adec6 290 Pfam PF01040 UbiA prenyltransferase family 20 251 2.0E-32 T 06-07-2017 IPR000537 UbiA prenyltransferase family GO:0004659|GO:0016021 CAK77_RS19825 acd57cc1abd73005a506ef8fea8adec6 290 Hamap MF_01937 1,4-dihydroxy-2-naphthoate octaprenyltransferase [menA]. 3 286 20.353 T 06-07-2017 IPR004657 1,4-dihydroxy-2-naphthoate octaprenyltransferase GO:0009234|GO:0016021|GO:0046428 KEGG: 00130+2.5.1.74|MetaCyc: PWY-5839|MetaCyc: PWY-5851|MetaCyc: PWY-5852|MetaCyc: PWY-5853|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 CAK77_RS19825 acd57cc1abd73005a506ef8fea8adec6 290 PIRSF PIRSF005355 1 289 4.7E-82 T 06-07-2017 IPR026046 UbiA prenyltransferase domain containing protein 1 GO:0004659 Reactome: R-HSA-6806664 CAK77_RS19825 acd57cc1abd73005a506ef8fea8adec6 290 TIGRFAM TIGR00751 menA: 1,4-dihydroxy-2-naphthoate octaprenyltransferase 12 284 3.5E-97 T 06-07-2017 CAK77_RS14725 75b0b82c1a44df539d033c167d75ce1d 198 SUPERFAMILY SSF53335 43 184 1.3E-32 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS14725 75b0b82c1a44df539d033c167d75ce1d 198 Gene3D G3DSA:3.40.50.150 44 184 2.1E-30 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS14725 75b0b82c1a44df539d033c167d75ce1d 198 Pfam PF13847 Methyltransferase domain 51 159 2.0E-17 T 06-07-2017 IPR025714 Methyltransferase domain CAK77_RS17400 0b3076301780e7c3bb849572c1715514 300 Pfam PF02687 FtsX-like permease family 179 291 2.7E-9 T 06-07-2017 IPR003838 ABC transporter permease protein domain GO:0016020 CAK77_RS17400 0b3076301780e7c3bb849572c1715514 300 PIRSF PIRSF003097 1 300 1.5E-58 T 06-07-2017 IPR004513 Cell division protein FtsX GO:0007049|GO:0016021 CAK77_RS00475 b2a7daa6abd552fe1d3c1710294b267d 415 SUPERFAMILY SSF56601 35 403 4.06E-66 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK77_RS00475 b2a7daa6abd552fe1d3c1710294b267d 415 Gene3D G3DSA:3.40.710.10 31 407 1.1E-65 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK77_RS00475 b2a7daa6abd552fe1d3c1710294b267d 415 Pfam PF00144 Beta-lactamase 47 404 1.3E-66 T 06-07-2017 IPR001466 Beta-lactamase-related CAK77_RS22055 c8a96370ae505c7c7ecc94635752e698 641 Pfam PF00890 FAD binding domain 10 433 1.0E-87 T 06-07-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK77_RS22055 c8a96370ae505c7c7ecc94635752e698 641 PIRSF PIRSF000171 1 599 1.0E-37 T 06-07-2017 IPR030664 Succinate dehydrogenase/fumarate reductase, alpha/adenylylsulphate reductase subunit Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK77_RS22055 c8a96370ae505c7c7ecc94635752e698 641 Pfam PF02910 Fumarate reductase flavoprotein C-term 491 592 9.8E-25 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK77_RS22055 c8a96370ae505c7c7ecc94635752e698 641 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 397 419 1.6E-5 T 06-07-2017 CAK77_RS22055 c8a96370ae505c7c7ecc94635752e698 641 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 1.6E-5 T 06-07-2017 CAK77_RS22055 c8a96370ae505c7c7ecc94635752e698 641 SUPERFAMILY SSF51905 4 274 2.33E-69 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS22055 c8a96370ae505c7c7ecc94635752e698 641 SUPERFAMILY SSF51905 397 472 2.33E-69 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS22055 c8a96370ae505c7c7ecc94635752e698 641 SUPERFAMILY SSF46977 483 637 6.15E-43 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK77_RS22055 c8a96370ae505c7c7ecc94635752e698 641 Gene3D G3DSA:3.90.700.10 254 387 6.4E-36 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK77_RS22055 c8a96370ae505c7c7ecc94635752e698 641 SUPERFAMILY SSF56425 247 393 2.09E-31 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK77_RS22055 c8a96370ae505c7c7ecc94635752e698 641 Gene3D G3DSA:1.20.58.100 481 579 9.8E-32 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK77_RS22055 c8a96370ae505c7c7ecc94635752e698 641 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 10 32 2.1E-6 T 06-07-2017 CAK77_RS22055 c8a96370ae505c7c7ecc94635752e698 641 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 442 462 2.1E-6 T 06-07-2017 CAK77_RS22055 c8a96370ae505c7c7ecc94635752e698 641 Gene3D G3DSA:3.50.50.60 389 454 3.0E-101 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS22055 c8a96370ae505c7c7ecc94635752e698 641 Gene3D G3DSA:3.50.50.60 3 253 3.0E-101 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS15525 e58a43ab001d9188b27d1a1f82000347 390 SUPERFAMILY SSF47203 238 387 3.22E-35 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS15525 e58a43ab001d9188b27d1a1f82000347 390 Gene3D G3DSA:1.10.540.10 24 141 4.7E-24 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS15525 e58a43ab001d9188b27d1a1f82000347 390 Gene3D G3DSA:1.20.140.10 225 388 6.6E-33 T 06-07-2017 CAK77_RS15525 e58a43ab001d9188b27d1a1f82000347 390 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 237 387 1.3E-24 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS15525 e58a43ab001d9188b27d1a1f82000347 390 Gene3D G3DSA:2.40.110.10 154 224 1.9E-8 T 06-07-2017 CAK77_RS15525 e58a43ab001d9188b27d1a1f82000347 390 SUPERFAMILY SSF56645 23 234 1.15E-35 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK77_RS15525 e58a43ab001d9188b27d1a1f82000347 390 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 27 139 2.7E-19 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS04830 38d0d8ae6fd26d3538681201e72dad81 147 Pfam PF03061 Thioesterase superfamily 28 107 6.2E-12 T 06-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 CAK77_RS04830 38d0d8ae6fd26d3538681201e72dad81 147 Gene3D G3DSA:3.10.129.10 3 146 3.7E-44 T 06-07-2017 IPR029069 HotDog domain CAK77_RS04830 38d0d8ae6fd26d3538681201e72dad81 147 SUPERFAMILY SSF54637 9 145 1.45E-35 T 06-07-2017 IPR029069 HotDog domain CAK77_RS03680 89d9136cb8ff9bfe1a106a3e4eaf4f7f 504 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 16 468 2.4E-163 T 06-07-2017 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 CAK77_RS03680 89d9136cb8ff9bfe1a106a3e4eaf4f7f 504 PIRSF PIRSF000485 12 482 3.4E-160 T 06-07-2017 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 CAK77_RS03680 89d9136cb8ff9bfe1a106a3e4eaf4f7f 504 Pfam PF00156 Phosphoribosyl transferase domain 283 392 5.8E-8 T 06-07-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 CAK77_RS03680 89d9136cb8ff9bfe1a106a3e4eaf4f7f 504 Pfam PF13522 Glutamine amidotransferase domain 74 216 1.5E-14 T 06-07-2017 CAK77_RS03680 89d9136cb8ff9bfe1a106a3e4eaf4f7f 504 SUPERFAMILY SSF56235 16 274 5.66E-65 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAK77_RS03680 89d9136cb8ff9bfe1a106a3e4eaf4f7f 504 SUPERFAMILY SSF53271 257 475 1.44E-66 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like CAK77_RS03680 89d9136cb8ff9bfe1a106a3e4eaf4f7f 504 Gene3D G3DSA:3.60.20.10 16 263 7.2E-64 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAK77_RS03680 89d9136cb8ff9bfe1a106a3e4eaf4f7f 504 Gene3D G3DSA:3.40.50.2020 279 449 9.5E-43 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like CAK77_RS03680 89d9136cb8ff9bfe1a106a3e4eaf4f7f 504 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 15 469 46.243 T 06-07-2017 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 CAK77_RS05795 177f19d810f4ee3fbba810bfe84bf1ac 292 SUPERFAMILY SSF53474 22 277 1.92E-44 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS05795 177f19d810f4ee3fbba810bfe84bf1ac 292 PRINTS PR00111 Alpha/beta hydrolase fold signature 127 140 1.8E-7 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS05795 177f19d810f4ee3fbba810bfe84bf1ac 292 PRINTS PR00111 Alpha/beta hydrolase fold signature 67 82 1.8E-7 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS05795 177f19d810f4ee3fbba810bfe84bf1ac 292 PRINTS PR00111 Alpha/beta hydrolase fold signature 113 126 1.8E-7 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS05795 177f19d810f4ee3fbba810bfe84bf1ac 292 PRINTS PR00111 Alpha/beta hydrolase fold signature 224 238 1.8E-7 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS05795 177f19d810f4ee3fbba810bfe84bf1ac 292 Gene3D G3DSA:3.40.50.1820 23 278 1.5E-45 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS05795 177f19d810f4ee3fbba810bfe84bf1ac 292 Pfam PF00561 alpha/beta hydrolase fold 42 144 6.5E-24 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS10995 d59b7826a30f62dfdab85334f9d79c84 862 Gene3D G3DSA:3.40.50.300 615 844 1.1E-75 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS10995 d59b7826a30f62dfdab85334f9d79c84 862 SMART SM00382 640 825 1.2E-18 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS10995 d59b7826a30f62dfdab85334f9d79c84 862 Pfam PF08021 Siderophore-interacting FAD-binding domain 52 113 8.6E-10 T 06-07-2017 IPR013113 FAD-binding 9, siderophore-interacting CAK77_RS10995 d59b7826a30f62dfdab85334f9d79c84 862 SUPERFAMILY SSF63380 16 112 2.1E-8 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CAK77_RS10995 d59b7826a30f62dfdab85334f9d79c84 862 ProSitePatterns PS00211 ABC transporters family signature. 751 765 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK77_RS10995 d59b7826a30f62dfdab85334f9d79c84 862 Pfam PF00005 ABC transporter 632 779 7.4E-32 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK77_RS10995 d59b7826a30f62dfdab85334f9d79c84 862 Gene3D G3DSA:3.40.50.80 128 247 6.7E-29 T 06-07-2017 CAK77_RS10995 d59b7826a30f62dfdab85334f9d79c84 862 Pfam PF00664 ABC transporter transmembrane region 300 567 4.0E-19 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAK77_RS10995 d59b7826a30f62dfdab85334f9d79c84 862 Pfam PF04954 Siderophore-interacting protein 130 238 2.8E-22 T 06-07-2017 IPR007037 Siderophore-interacting protein CAK77_RS10995 d59b7826a30f62dfdab85334f9d79c84 862 Gene3D G3DSA:1.20.1560.10 292 597 3.0E-34 T 06-07-2017 CAK77_RS10995 d59b7826a30f62dfdab85334f9d79c84 862 SUPERFAMILY SSF52540 611 847 2.44E-82 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS10995 d59b7826a30f62dfdab85334f9d79c84 862 Gene3D G3DSA:2.40.30.10 16 113 4.2E-21 T 06-07-2017 CAK77_RS10995 d59b7826a30f62dfdab85334f9d79c84 862 SUPERFAMILY SSF90123 292 601 1.44E-42 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAK77_RS13145 9772606731d22f1ef3db4215bb52aef8 498 Gene3D G3DSA:3.50.50.60 15 325 4.9E-22 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS13145 9772606731d22f1ef3db4215bb52aef8 498 SUPERFAMILY SSF51905 15 266 2.59E-19 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS13145 9772606731d22f1ef3db4215bb52aef8 498 Hamap MF_00212 Probable malate:quinone oxidoreductase [mqo]. 11 491 42.798 T 06-07-2017 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 CAK77_RS13145 9772606731d22f1ef3db4215bb52aef8 498 Pfam PF06039 Malate:quinone oxidoreductase (Mqo) 15 489 2.2E-183 T 06-07-2017 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 CAK77_RS13145 9772606731d22f1ef3db4215bb52aef8 498 TIGRFAM TIGR01320 mal_quin_oxido: malate dehydrogenase (acceptor) 15 483 1.8E-166 T 06-07-2017 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 CAK77_RS13750 9e2e0900b87b6d59d9cd38013761f6a7 205 SUPERFAMILY SSF46689 13 82 1.36E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS13750 9e2e0900b87b6d59d9cd38013761f6a7 205 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 67 1.4E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS13750 9e2e0900b87b6d59d9cd38013761f6a7 205 Gene3D G3DSA:1.10.357.10 10 190 1.1E-20 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS08740 014ac0f9d1d32758a241ec25ab0d14bc 271 Pfam PF02361 Cobalt transport protein 20 238 3.9E-31 T 06-07-2017 IPR003339 ABC/ECF transporter, transmembrane component CAK77_RS13385 237993994e5287fd6f572b30bb9c32b3 176 SUPERFAMILY SSF109854 22 167 4.58E-24 T 06-07-2017 CAK77_RS13385 237993994e5287fd6f572b30bb9c32b3 176 Gene3D G3DSA:1.20.120.450 25 171 3.6E-19 T 06-07-2017 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase CAK77_RS13385 237993994e5287fd6f572b30bb9c32b3 176 Pfam PF12867 DinB superfamily 47 166 4.0E-6 T 06-07-2017 IPR024775 DinB-like domain CAK77_RS13700 b9d19e43d608e8c575d43529e038eeaa 220 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 36 216 4.2E-14 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS13700 b9d19e43d608e8c575d43529e038eeaa 220 Gene3D G3DSA:1.10.3720.10 9 217 6.9E-31 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS13700 b9d19e43d608e8c575d43529e038eeaa 220 SUPERFAMILY SSF161098 10 205 9.68E-36 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS16450 d97a15b14b700de19f83c5c2931e978f 400 Gene3D G3DSA:1.20.1250.20 215 391 1.6E-16 T 06-07-2017 CAK77_RS16450 d97a15b14b700de19f83c5c2931e978f 400 Gene3D G3DSA:1.20.1250.20 14 203 7.5E-32 T 06-07-2017 CAK77_RS16450 d97a15b14b700de19f83c5c2931e978f 400 SUPERFAMILY SSF103473 11 393 6.02E-59 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK77_RS16450 d97a15b14b700de19f83c5c2931e978f 400 Pfam PF07690 Major Facilitator Superfamily 27 351 4.8E-37 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK77_RS03580 9f0b4e597d91f8d7f55a57642144abd8 273 SUPERFAMILY SSF51735 4 133 4.06E-36 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS03580 9f0b4e597d91f8d7f55a57642144abd8 273 SUPERFAMILY SSF51735 162 265 4.06E-36 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS03580 9f0b4e597d91f8d7f55a57642144abd8 273 Pfam PF00106 short chain dehydrogenase 5 136 1.8E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS03580 9f0b4e597d91f8d7f55a57642144abd8 273 Gene3D G3DSA:3.40.50.720 3 264 1.7E-40 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS03580 9f0b4e597d91f8d7f55a57642144abd8 273 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 164 262 1.1E-22 T 06-07-2017 CAK77_RS03580 9f0b4e597d91f8d7f55a57642144abd8 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 5.0E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS03580 9f0b4e597d91f8d7f55a57642144abd8 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 5.0E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS03580 9f0b4e597d91f8d7f55a57642144abd8 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 226 246 5.0E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS03580 9f0b4e597d91f8d7f55a57642144abd8 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 187 5.0E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS03580 9f0b4e597d91f8d7f55a57642144abd8 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 114 130 5.0E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS03580 9f0b4e597d91f8d7f55a57642144abd8 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 189 206 5.0E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS17045 8eac5100c299324cc303096e43c0f0ce 294 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 2.8E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS17045 8eac5100c299324cc303096e43c0f0ce 294 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 2.8E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS17045 8eac5100c299324cc303096e43c0f0ce 294 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 2.8E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS17045 8eac5100c299324cc303096e43c0f0ce 294 Pfam PF00106 short chain dehydrogenase 10 198 3.8E-52 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS17045 8eac5100c299324cc303096e43c0f0ce 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 5.7E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS17045 8eac5100c299324cc303096e43c0f0ce 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 5.7E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS17045 8eac5100c299324cc303096e43c0f0ce 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 5.7E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS17045 8eac5100c299324cc303096e43c0f0ce 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 5.7E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS17045 8eac5100c299324cc303096e43c0f0ce 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 5.7E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS17045 8eac5100c299324cc303096e43c0f0ce 294 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK77_RS17045 8eac5100c299324cc303096e43c0f0ce 294 Gene3D G3DSA:3.40.50.720 6 251 5.6E-67 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS17045 8eac5100c299324cc303096e43c0f0ce 294 SUPERFAMILY SSF51735 3 269 1.15E-65 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS13740 1fb982825ebab5e0d2e6658add4efa51 471 SUPERFAMILY SSF53335 171 469 1.19E-51 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS13740 1fb982825ebab5e0d2e6658add4efa51 471 SUPERFAMILY SSF48013 31 184 3.27E-30 T 06-07-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CAK77_RS13740 1fb982825ebab5e0d2e6658add4efa51 471 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 287 297 8.0E-24 T 06-07-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CAK77_RS13740 1fb982825ebab5e0d2e6658add4efa51 471 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 254 268 8.0E-24 T 06-07-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CAK77_RS13740 1fb982825ebab5e0d2e6658add4efa51 471 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 351 363 8.0E-24 T 06-07-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CAK77_RS13740 1fb982825ebab5e0d2e6658add4efa51 471 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 452 469 8.0E-24 T 06-07-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CAK77_RS13740 1fb982825ebab5e0d2e6658add4efa51 471 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 401 417 8.0E-24 T 06-07-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CAK77_RS13740 1fb982825ebab5e0d2e6658add4efa51 471 Pfam PF01029 NusB family 31 153 1.1E-22 T 06-07-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CAK77_RS13740 1fb982825ebab5e0d2e6658add4efa51 471 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 350 361 - T 06-07-2017 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CAK77_RS13740 1fb982825ebab5e0d2e6658add4efa51 471 Gene3D G3DSA:3.40.50.150 274 469 8.2E-47 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS13740 1fb982825ebab5e0d2e6658add4efa51 471 Pfam PF01189 16S rRNA methyltransferase RsmB/F 279 468 4.7E-55 T 06-07-2017 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CAK77_RS13740 1fb982825ebab5e0d2e6658add4efa51 471 Gene3D G3DSA:1.10.940.10 29 185 3.3E-43 T 06-07-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CAK77_RS16725 3ce7e03bcb2d59f7770d8bb2b59326ef 263 ProSitePatterns PS01065 Electron transfer flavoprotein beta-subunit signature. 160 180 - T 06-07-2017 IPR000049 Electron transfer flavoprotein, beta-subunit, conserved site GO:0009055 Reactome: R-HSA-611105 CAK77_RS16725 3ce7e03bcb2d59f7770d8bb2b59326ef 263 SUPERFAMILY SSF52402 3 257 2.3E-64 T 06-07-2017 CAK77_RS16725 3ce7e03bcb2d59f7770d8bb2b59326ef 263 Pfam PF01012 Electron transfer flavoprotein domain 25 211 5.9E-39 T 06-07-2017 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CAK77_RS16725 3ce7e03bcb2d59f7770d8bb2b59326ef 263 Gene3D G3DSA:3.40.50.620 3 262 2.0E-78 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS16725 3ce7e03bcb2d59f7770d8bb2b59326ef 263 SMART SM00893 24 216 1.6E-47 T 06-07-2017 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CAK77_RS16725 3ce7e03bcb2d59f7770d8bb2b59326ef 263 PIRSF PIRSF000090 2 263 1.8E-77 T 06-07-2017 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105 CAK77_RS10415 9ea5709e0a1fc5a84b77ca3113ddac14 178 TIGRFAM TIGR01971 NuoI: NADH-quinone oxidoreductase, chain I 14 141 3.2E-43 T 06-07-2017 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS10415 9ea5709e0a1fc5a84b77ca3113ddac14 178 SUPERFAMILY SSF54862 31 148 1.34E-27 T 06-07-2017 CAK77_RS10415 9ea5709e0a1fc5a84b77ca3113ddac14 178 Hamap MF_01351 NAD(P)H-quinone oxidoreductase subunit I, chloroplastic [ndhI]. 5 151 27.406 T 06-07-2017 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS10415 9ea5709e0a1fc5a84b77ca3113ddac14 178 Gene3D G3DSA:1.10.1060.10 13 123 5.7E-20 T 06-07-2017 CAK77_RS10415 9ea5709e0a1fc5a84b77ca3113ddac14 178 Pfam PF12838 4Fe-4S dicluster domain 57 117 4.6E-12 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CAK77_RS10415 9ea5709e0a1fc5a84b77ca3113ddac14 178 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 58 69 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CAK77_RS10415 9ea5709e0a1fc5a84b77ca3113ddac14 178 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 103 114 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CAK77_RS10930 9d1781fbd06fd1b114635e88531242f6 292 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 111 281 2.1E-18 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS10930 9d1781fbd06fd1b114635e88531242f6 292 SUPERFAMILY SSF161098 88 268 3.66E-27 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS10930 9d1781fbd06fd1b114635e88531242f6 292 Gene3D G3DSA:1.10.3720.10 87 281 1.4E-20 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS04825 beabbf7bd7ef7e0e706f2d9afcc776ca 221 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 94 114 - T 06-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CAK77_RS04825 beabbf7bd7ef7e0e706f2d9afcc776ca 221 Pfam PF00378 Enoyl-CoA hydratase/isomerase 19 208 1.4E-26 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAK77_RS04825 beabbf7bd7ef7e0e706f2d9afcc776ca 221 SUPERFAMILY SSF52096 4 210 3.95E-46 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS04825 beabbf7bd7ef7e0e706f2d9afcc776ca 221 Gene3D G3DSA:3.90.226.10 4 192 5.5E-41 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS12460 5e3bc7fc9d1cb90e7403276379b9f3a6 268 SUPERFAMILY SSF52402 9 144 1.17E-25 T 06-07-2017 CAK77_RS12460 5e3bc7fc9d1cb90e7403276379b9f3a6 268 Gene3D G3DSA:3.40.50.620 8 144 1.4E-26 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS12460 5e3bc7fc9d1cb90e7403276379b9f3a6 268 Pfam PF00582 Universal stress protein family 10 141 7.8E-21 T 06-07-2017 IPR006016 UspA GO:0006950 CAK77_RS12460 5e3bc7fc9d1cb90e7403276379b9f3a6 268 PRINTS PR01438 Universal stress protein signature 7 25 3.6E-11 T 06-07-2017 IPR006015 Universal stress protein A CAK77_RS12460 5e3bc7fc9d1cb90e7403276379b9f3a6 268 PRINTS PR01438 Universal stress protein signature 101 113 3.6E-11 T 06-07-2017 IPR006015 Universal stress protein A CAK77_RS12460 5e3bc7fc9d1cb90e7403276379b9f3a6 268 PRINTS PR01438 Universal stress protein signature 119 141 3.6E-11 T 06-07-2017 IPR006015 Universal stress protein A CAK77_RS21215 8a7286403064621cc23e34a850183a59 370 SUPERFAMILY SSF51679 4 114 9.52E-64 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS21215 8a7286403064621cc23e34a850183a59 370 SUPERFAMILY SSF51679 155 366 9.52E-64 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS21215 8a7286403064621cc23e34a850183a59 370 Pfam PF00296 Luciferase-like monooxygenase 181 337 2.7E-10 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS21215 8a7286403064621cc23e34a850183a59 370 Pfam PF00296 Luciferase-like monooxygenase 17 120 1.9E-23 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS21215 8a7286403064621cc23e34a850183a59 370 Gene3D G3DSA:3.20.20.30 155 366 1.5E-90 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS21215 8a7286403064621cc23e34a850183a59 370 Gene3D G3DSA:3.20.20.30 4 114 1.5E-90 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS13230 fb0bed0f34fe5dc6d3238a224e7a14c1 195 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 13 165 15.593 T 06-07-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CAK77_RS13230 fb0bed0f34fe5dc6d3238a224e7a14c1 195 Pfam PF01252 Signal peptidase (SPase) II 22 160 4.8E-30 T 06-07-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CAK77_RS13230 fb0bed0f34fe5dc6d3238a224e7a14c1 195 TIGRFAM TIGR00077 lspA: signal peptidase II 17 160 1.6E-27 T 06-07-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CAK77_RS13230 fb0bed0f34fe5dc6d3238a224e7a14c1 195 ProSitePatterns PS00855 Signal peptidases II signature. 105 117 - T 06-07-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CAK77_RS13230 fb0bed0f34fe5dc6d3238a224e7a14c1 195 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 102 117 4.4E-16 T 06-07-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CAK77_RS13230 fb0bed0f34fe5dc6d3238a224e7a14c1 195 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 60 68 4.4E-16 T 06-07-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CAK77_RS13230 fb0bed0f34fe5dc6d3238a224e7a14c1 195 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 140 156 4.4E-16 T 06-07-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CAK77_RS10260 2bd1be3fc783c25389f26416efc4fe38 272 TIGRFAM TIGR03843 TIGR03843: conserved hypothetical protein 17 272 5.0E-111 T 06-07-2017 IPR022292 Conserved hypothetical protein CHP03843 CAK77_RS22325 02c4ed328746fd2b8959622f29129a20 378 SUPERFAMILY SSF159245 22 252 1.22E-7 T 06-07-2017 CAK77_RS06080 f3301a82fbd8f3c523183ff37bcdb8f8 418 Pfam PF00067 Cytochrome P450 290 382 1.7E-14 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS06080 f3301a82fbd8f3c523183ff37bcdb8f8 418 SUPERFAMILY SSF48264 26 404 6.42E-76 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS06080 f3301a82fbd8f3c523183ff37bcdb8f8 418 PRINTS PR00359 B-class P450 signature 171 186 4.9E-46 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS06080 f3301a82fbd8f3c523183ff37bcdb8f8 418 PRINTS PR00359 B-class P450 signature 306 333 4.9E-46 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS06080 f3301a82fbd8f3c523183ff37bcdb8f8 418 PRINTS PR00359 B-class P450 signature 210 232 4.9E-46 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS06080 f3301a82fbd8f3c523183ff37bcdb8f8 418 PRINTS PR00359 B-class P450 signature 356 365 4.9E-46 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS06080 f3301a82fbd8f3c523183ff37bcdb8f8 418 PRINTS PR00359 B-class P450 signature 365 376 4.9E-46 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS06080 f3301a82fbd8f3c523183ff37bcdb8f8 418 PRINTS PR00359 B-class P450 signature 108 119 4.9E-46 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS06080 f3301a82fbd8f3c523183ff37bcdb8f8 418 PRINTS PR00359 B-class P450 signature 334 349 4.9E-46 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS06080 f3301a82fbd8f3c523183ff37bcdb8f8 418 PRINTS PR00359 B-class P450 signature 154 170 4.9E-46 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS06080 f3301a82fbd8f3c523183ff37bcdb8f8 418 PRINTS PR00359 B-class P450 signature 289 300 4.9E-46 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS06080 f3301a82fbd8f3c523183ff37bcdb8f8 418 Gene3D G3DSA:1.10.630.10 11 409 7.3E-105 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS15050 bf86da37e140edfeefb2bd9b2d2aa3a1 125 SUPERFAMILY SSF56399 11 117 2.07E-25 T 06-07-2017 CAK77_RS15050 bf86da37e140edfeefb2bd9b2d2aa3a1 125 Pfam PF06108 Protein of unknown function (DUF952) 15 106 7.8E-24 T 06-07-2017 IPR009297 Protein of unknown function DUF952 CAK77_RS03440 1c6034ac0df67d540d3d06e8777c2200 102 ProDom PD195452 PE FAMILY PRECURSOR PE-FAMILY SIGNAL PE15 PE_1 44 97 8.0E-8 T 06-07-2017 CAK77_RS03440 1c6034ac0df67d540d3d06e8777c2200 102 Pfam PF00934 PE family 3 90 1.2E-20 T 06-07-2017 IPR000084 PE-PGRS family, N-terminal CAK77_RS03440 1c6034ac0df67d540d3d06e8777c2200 102 SUPERFAMILY SSF140459 7 72 1.83E-13 T 06-07-2017 CAK77_RS19290 88ee9ba5dd2a19f801310f79fb4da261 96 SUPERFAMILY SSF141694 10 91 3.14E-20 T 06-07-2017 CAK77_RS19290 88ee9ba5dd2a19f801310f79fb4da261 96 Pfam PF08922 Domain of unknown function (DUF1905) 12 88 1.2E-19 T 06-07-2017 IPR015018 Protein of unknown function DUF1905 CAK77_RS19290 88ee9ba5dd2a19f801310f79fb4da261 96 Gene3D G3DSA:2.40.30.100 10 90 3.1E-25 T 06-07-2017 CAK77_RS06195 15f8a2d79ca98f5c5f29f10613d8cb1c 310 SUPERFAMILY SSF52540 5 308 2.95E-69 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS06195 15f8a2d79ca98f5c5f29f10613d8cb1c 310 PIRSF PIRSF000545 1 310 7.9E-142 T 06-07-2017 IPR004566 Bacterial pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CAK77_RS06195 15f8a2d79ca98f5c5f29f10613d8cb1c 310 TIGRFAM TIGR00554 panK_bact: pantothenate kinase 9 309 1.2E-122 T 06-07-2017 IPR004566 Bacterial pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CAK77_RS06195 15f8a2d79ca98f5c5f29f10613d8cb1c 310 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 90 241 5.6E-13 T 06-07-2017 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 CAK77_RS06195 15f8a2d79ca98f5c5f29f10613d8cb1c 310 Gene3D G3DSA:3.40.50.300 8 309 2.0E-103 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS06195 15f8a2d79ca98f5c5f29f10613d8cb1c 310 Hamap MF_00215 Pantothenate kinase [coaA]. 1 310 176.769 T 06-07-2017 IPR004566 Bacterial pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CAK77_RS09920 8d4db85854b46adc6587f21c06b7280a 187 Pfam PF00440 Bacterial regulatory proteins, tetR family 1 43 3.1E-13 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS09920 8d4db85854b46adc6587f21c06b7280a 187 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 1 14 1.6E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS09920 8d4db85854b46adc6587f21c06b7280a 187 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 45 1.6E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS09920 8d4db85854b46adc6587f21c06b7280a 187 Gene3D G3DSA:1.10.357.10 1 176 3.5E-27 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS09920 8d4db85854b46adc6587f21c06b7280a 187 SUPERFAMILY SSF46689 1 69 5.49E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS20135 20830e9808fcaff4e242e908bac8f5ac 607 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 480 499 2.5E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS20135 20830e9808fcaff4e242e908bac8f5ac 607 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 406 417 2.5E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS20135 20830e9808fcaff4e242e908bac8f5ac 607 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 460 468 2.5E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS20135 20830e9808fcaff4e242e908bac8f5ac 607 SUPERFAMILY SSF51735 327 592 2.85E-66 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS20135 20830e9808fcaff4e242e908bac8f5ac 607 Gene3D G3DSA:3.40.50.720 330 566 3.2E-65 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS20135 20830e9808fcaff4e242e908bac8f5ac 607 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 331 506 0.0038 T 06-07-2017 CAK77_RS20135 20830e9808fcaff4e242e908bac8f5ac 607 SUPERFAMILY SSF53474 15 303 2.29E-42 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS20135 20830e9808fcaff4e242e908bac8f5ac 607 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 406 417 5.6E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS20135 20830e9808fcaff4e242e908bac8f5ac 607 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 332 349 5.6E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS20135 20830e9808fcaff4e242e908bac8f5ac 607 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 501 518 5.6E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS20135 20830e9808fcaff4e242e908bac8f5ac 607 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 454 470 5.6E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS20135 20830e9808fcaff4e242e908bac8f5ac 607 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 480 499 5.6E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS20135 20830e9808fcaff4e242e908bac8f5ac 607 Pfam PF00106 short chain dehydrogenase 332 520 3.9E-50 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS20135 20830e9808fcaff4e242e908bac8f5ac 607 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 467 495 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK77_RS20135 20830e9808fcaff4e242e908bac8f5ac 607 Pfam PF00561 alpha/beta hydrolase fold 40 156 9.3E-19 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS20135 20830e9808fcaff4e242e908bac8f5ac 607 Gene3D G3DSA:3.40.50.1820 15 304 6.9E-45 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS02810 6102a987bf4c6a8b27d059dae4ccdf69 322 Gene3D G3DSA:3.40.50.720 28 191 4.8E-34 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS02810 6102a987bf4c6a8b27d059dae4ccdf69 322 Gene3D G3DSA:1.10.1040.20 194 306 2.0E-26 T 06-07-2017 IPR018931 Domain of unknown function DUF2520 CAK77_RS02810 6102a987bf4c6a8b27d059dae4ccdf69 322 Pfam PF10728 Domain of unknown function (DUF2520) 161 302 1.1E-37 T 06-07-2017 IPR018931 Domain of unknown function DUF2520 CAK77_RS02810 6102a987bf4c6a8b27d059dae4ccdf69 322 SUPERFAMILY SSF48179 194 307 3.2E-19 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAK77_RS02810 6102a987bf4c6a8b27d059dae4ccdf69 322 SUPERFAMILY SSF51735 29 192 8.26E-24 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS02810 6102a987bf4c6a8b27d059dae4ccdf69 322 Pfam PF10727 Rossmann-like domain 23 143 3.0E-54 T 06-07-2017 IPR019665 Putative oxidoreductase/dehydrogenase, Rossmann-like domain CAK77_RS22830 b96bfa4d498590af183dd5ff9223abea 310 Pfam PF04072 Leucine carboxyl methyltransferase 19 199 2.2E-52 T 06-07-2017 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 CAK77_RS22830 b96bfa4d498590af183dd5ff9223abea 310 Gene3D G3DSA:3.40.50.150 17 230 2.0E-15 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS22830 b96bfa4d498590af183dd5ff9223abea 310 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 17 285 2.6E-80 T 06-07-2017 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 CAK77_RS22830 b96bfa4d498590af183dd5ff9223abea 310 SUPERFAMILY SSF53335 15 289 1.99E-70 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS19780 6e38cf81d334562df9dc15ad597305c0 434 Pfam PF01384 Phosphate transporter family 22 174 6.2E-36 T 06-07-2017 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 CAK77_RS19780 6e38cf81d334562df9dc15ad597305c0 434 Pfam PF01384 Phosphate transporter family 179 336 6.3E-44 T 06-07-2017 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 CAK77_RS14180 f9b7a0d55fcb3ef25ef97283c4436b78 684 SUPERFAMILY SSF55681 261 558 6.89E-90 T 06-07-2017 CAK77_RS14180 f9b7a0d55fcb3ef25ef97283c4436b78 684 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 192 237 3.8E-11 T 06-07-2017 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CAK77_RS14180 f9b7a0d55fcb3ef25ef97283c4436b78 684 Pfam PF03129 Anticodon binding domain 574 662 1.3E-15 T 06-07-2017 IPR004154 Anticodon-binding CAK77_RS14180 f9b7a0d55fcb3ef25ef97283c4436b78 684 SUPERFAMILY SSF52954 562 668 1.3E-26 T 06-07-2017 IPR004154 Anticodon-binding CAK77_RS14180 f9b7a0d55fcb3ef25ef97283c4436b78 684 Gene3D G3DSA:3.30.54.20 136 205 3.4E-9 T 06-07-2017 CAK77_RS14180 f9b7a0d55fcb3ef25ef97283c4436b78 684 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 75 661 2.6E-189 T 06-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CAK77_RS14180 f9b7a0d55fcb3ef25ef97283c4436b78 684 Gene3D G3DSA:3.30.930.10 260 563 3.6E-101 T 06-07-2017 CAK77_RS14180 f9b7a0d55fcb3ef25ef97283c4436b78 684 PRINTS PR01047 Threonyl-tRNA synthetase signature 394 417 1.9E-51 T 06-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CAK77_RS14180 f9b7a0d55fcb3ef25ef97283c4436b78 684 PRINTS PR01047 Threonyl-tRNA synthetase signature 567 579 1.9E-51 T 06-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CAK77_RS14180 f9b7a0d55fcb3ef25ef97283c4436b78 684 PRINTS PR01047 Threonyl-tRNA synthetase signature 540 553 1.9E-51 T 06-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CAK77_RS14180 f9b7a0d55fcb3ef25ef97283c4436b78 684 PRINTS PR01047 Threonyl-tRNA synthetase signature 497 525 1.9E-51 T 06-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CAK77_RS14180 f9b7a0d55fcb3ef25ef97283c4436b78 684 PRINTS PR01047 Threonyl-tRNA synthetase signature 361 389 1.9E-51 T 06-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CAK77_RS14180 f9b7a0d55fcb3ef25ef97283c4436b78 684 Gene3D G3DSA:3.30.980.10 206 242 2.6E-39 T 06-07-2017 CAK77_RS14180 f9b7a0d55fcb3ef25ef97283c4436b78 684 Gene3D G3DSA:3.30.980.10 69 132 2.6E-39 T 06-07-2017 CAK77_RS14180 f9b7a0d55fcb3ef25ef97283c4436b78 684 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 356 562 2.9E-34 T 06-07-2017 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK77_RS14180 f9b7a0d55fcb3ef25ef97283c4436b78 684 SMART SM00863 181 237 6.0E-15 T 06-07-2017 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CAK77_RS14180 f9b7a0d55fcb3ef25ef97283c4436b78 684 SUPERFAMILY SSF55186 67 258 1.27E-51 T 06-07-2017 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 CAK77_RS14180 f9b7a0d55fcb3ef25ef97283c4436b78 684 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 69 667 32.854 T 06-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CAK77_RS14180 f9b7a0d55fcb3ef25ef97283c4436b78 684 Gene3D G3DSA:3.40.50.800 564 668 3.1E-28 T 06-07-2017 IPR004154 Anticodon-binding CAK77_RS04250 5b534118d9d0e30420921076fecb97e3 356 SUPERFAMILY SSF53901 226 346 3.07E-13 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS04250 5b534118d9d0e30420921076fecb97e3 356 Gene3D G3DSA:3.40.47.10 199 218 8.5E-5 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS04250 5b534118d9d0e30420921076fecb97e3 356 Gene3D G3DSA:3.40.47.10 20 119 8.5E-5 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS04250 5b534118d9d0e30420921076fecb97e3 356 SUPERFAMILY SSF53901 196 223 1.02E-9 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS04250 5b534118d9d0e30420921076fecb97e3 356 SUPERFAMILY SSF53901 1 116 1.02E-9 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS04250 5b534118d9d0e30420921076fecb97e3 356 PIRSF PIRSF000429 1 349 3.1E-8 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 CAK77_RS04250 5b534118d9d0e30420921076fecb97e3 356 Gene3D G3DSA:3.40.47.10 247 341 4.6E-5 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS04550 13e9704e0d7394a1ba36548f10db83c5 407 SUPERFAMILY SSF53448 21 232 3.0E-35 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK77_RS04550 13e9704e0d7394a1ba36548f10db83c5 407 Gene3D G3DSA:3.90.550.10 23 220 2.1E-21 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK77_RS04550 13e9704e0d7394a1ba36548f10db83c5 407 Pfam PF04138 GtrA-like protein 284 400 6.4E-9 T 06-07-2017 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 CAK77_RS04550 13e9704e0d7394a1ba36548f10db83c5 407 Pfam PF00535 Glycosyl transferase family 2 23 190 6.7E-21 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CAK77_RS19605 d9984d7345069fb08fe131682eb4f74d 340 SUPERFAMILY SSF51679 9 320 1.47E-50 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS19605 d9984d7345069fb08fe131682eb4f74d 340 TIGRFAM TIGR03617 F420_MSMEG_2256: probable F420-dependent oxidoreductase, MSMEG_2256 family 19 337 2.1E-129 T 06-07-2017 IPR019919 Luciferase-like, F420-dependent oxidoreductase, MSMEG2256, predicted CAK77_RS19605 d9984d7345069fb08fe131682eb4f74d 340 Gene3D G3DSA:3.20.20.30 11 333 1.2E-50 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS19605 d9984d7345069fb08fe131682eb4f74d 340 Pfam PF00296 Luciferase-like monooxygenase 11 314 4.3E-54 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS19155 1b770cd37770ffeb6ee5e800c5dcd289 398 Pfam PF14759 Reductase C-terminal 324 392 1.8E-11 T 06-07-2017 IPR028202 Reductase, C-terminal CAK77_RS19155 1b770cd37770ffeb6ee5e800c5dcd289 398 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 7.7E-20 T 06-07-2017 CAK77_RS19155 1b770cd37770ffeb6ee5e800c5dcd289 398 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 105 123 7.7E-20 T 06-07-2017 CAK77_RS19155 1b770cd37770ffeb6ee5e800c5dcd289 398 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 149 167 7.7E-20 T 06-07-2017 CAK77_RS19155 1b770cd37770ffeb6ee5e800c5dcd289 398 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 234 250 7.7E-20 T 06-07-2017 CAK77_RS19155 1b770cd37770ffeb6ee5e800c5dcd289 398 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 259 281 7.7E-20 T 06-07-2017 CAK77_RS19155 1b770cd37770ffeb6ee5e800c5dcd289 398 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 149 174 3.8E-13 T 06-07-2017 CAK77_RS19155 1b770cd37770ffeb6ee5e800c5dcd289 398 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 274 281 3.8E-13 T 06-07-2017 CAK77_RS19155 1b770cd37770ffeb6ee5e800c5dcd289 398 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 235 249 3.8E-13 T 06-07-2017 CAK77_RS19155 1b770cd37770ffeb6ee5e800c5dcd289 398 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 3.8E-13 T 06-07-2017 CAK77_RS19155 1b770cd37770ffeb6ee5e800c5dcd289 398 Gene3D G3DSA:3.30.390.30 324 392 1.3E-15 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CAK77_RS19155 1b770cd37770ffeb6ee5e800c5dcd289 398 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 297 1.5E-55 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS19155 1b770cd37770ffeb6ee5e800c5dcd289 398 SUPERFAMILY SSF51905 149 284 8.26E-27 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS19155 1b770cd37770ffeb6ee5e800c5dcd289 398 SUPERFAMILY SSF51905 5 185 1.99E-40 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS19155 1b770cd37770ffeb6ee5e800c5dcd289 398 Gene3D G3DSA:3.50.50.60 3 110 2.0E-31 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS19155 1b770cd37770ffeb6ee5e800c5dcd289 398 Gene3D G3DSA:3.50.50.60 111 242 3.0E-37 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS19155 1b770cd37770ffeb6ee5e800c5dcd289 398 SUPERFAMILY SSF55424 320 391 2.61E-17 T 06-07-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CAK77_RS10360 55cdfc7062a862ede56fe07d14b1a9d1 87 SUPERFAMILY SSF101386 2 87 9.72E-22 T 06-07-2017 CAK77_RS10360 55cdfc7062a862ede56fe07d14b1a9d1 87 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 9 86 5.5E-8 T 06-07-2017 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 CAK77_RS10360 55cdfc7062a862ede56fe07d14b1a9d1 87 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 1 87 18.246 T 06-07-2017 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 CAK77_RS10360 55cdfc7062a862ede56fe07d14b1a9d1 87 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 5 87 1.4E-23 T 06-07-2017 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 CAK77_RS23995 fcd1ec16bf8745de2b8e3d6cc6f8d891 316 Pfam PF12740 Chlorophyllase enzyme 37 151 1.6E-10 T 06-07-2017 IPR017395 Chlorophyllase GO:0015996|GO:0047746 KEGG: 00860+3.1.1.14|MetaCyc: PWY-5098|MetaCyc: PWY-6927|MetaCyc: PWY-7164 CAK77_RS23995 fcd1ec16bf8745de2b8e3d6cc6f8d891 316 Gene3D G3DSA:3.40.50.1820 18 289 4.6E-27 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS23995 fcd1ec16bf8745de2b8e3d6cc6f8d891 316 SUPERFAMILY SSF53474 22 254 3.41E-26 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS20790 7eb284a76351e12454984fa097d61888 509 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 8 295 9.0E-74 T 06-07-2017 IPR005693 Virulence factor Mce protein CAK77_RS20790 7eb284a76351e12454984fa097d61888 509 Pfam PF02470 MlaD protein 39 113 1.9E-17 T 06-07-2017 IPR003399 Mce/MlaD CAK77_RS12410 ec70f5a8e346d0d0a0eaf054053c7838 179 Pfam PF00857 Isochorismatase family 4 174 1.7E-23 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAK77_RS12410 ec70f5a8e346d0d0a0eaf054053c7838 179 SUPERFAMILY SSF52499 2 175 6.54E-34 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAK77_RS12410 ec70f5a8e346d0d0a0eaf054053c7838 179 Gene3D G3DSA:3.40.50.850 1 177 1.2E-33 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAK77_RS21415 1a851fbbc1f63058bcaea08aa391c634 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 5.8E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS21415 1a851fbbc1f63058bcaea08aa391c634 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 5.8E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS21415 1a851fbbc1f63058bcaea08aa391c634 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 5.8E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS21415 1a851fbbc1f63058bcaea08aa391c634 263 Gene3D G3DSA:3.40.50.720 9 232 3.5E-57 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS21415 1a851fbbc1f63058bcaea08aa391c634 263 PIRSF PIRSF000126 1 261 8.3E-62 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS21415 1a851fbbc1f63058bcaea08aa391c634 263 Pfam PF00106 short chain dehydrogenase 10 194 2.5E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS21415 1a851fbbc1f63058bcaea08aa391c634 263 SUPERFAMILY SSF51735 9 252 4.23E-56 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS21415 1a851fbbc1f63058bcaea08aa391c634 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 6.2E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS21415 1a851fbbc1f63058bcaea08aa391c634 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 6.2E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS21415 1a851fbbc1f63058bcaea08aa391c634 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 6.2E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS21415 1a851fbbc1f63058bcaea08aa391c634 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 6.2E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS21415 1a851fbbc1f63058bcaea08aa391c634 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 6.2E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS22905 e30db374383dd08070ecf0f49ef46f8f 149 SUPERFAMILY SSF54637 14 144 8.64E-38 T 06-07-2017 IPR029069 HotDog domain CAK77_RS22905 e30db374383dd08070ecf0f49ef46f8f 149 Pfam PF01575 MaoC like domain 20 126 9.0E-28 T 06-07-2017 IPR002539 MaoC-like domain CAK77_RS22905 e30db374383dd08070ecf0f49ef46f8f 149 Gene3D G3DSA:3.10.129.10 9 144 6.6E-38 T 06-07-2017 IPR029069 HotDog domain CAK77_RS10330 9c3b734e1d81bd8b56e93df7569d50b8 475 TIGRFAM TIGR03605 antibiot_sagB: SagB-type dehydrogenase domain 298 471 2.1E-44 T 06-07-2017 IPR020051 SagB-type dehydrogenase domain CAK77_RS10330 9c3b734e1d81bd8b56e93df7569d50b8 475 Gene3D G3DSA:3.40.109.10 277 473 2.0E-18 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CAK77_RS10330 9c3b734e1d81bd8b56e93df7569d50b8 475 SUPERFAMILY SSF55469 371 473 3.14E-17 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CAK77_RS10330 9c3b734e1d81bd8b56e93df7569d50b8 475 SUPERFAMILY SSF55469 279 343 3.14E-17 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CAK77_RS10330 9c3b734e1d81bd8b56e93df7569d50b8 475 Pfam PF00881 Nitroreductase family 282 470 1.1E-17 T 06-07-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 CAK77_RS09310 98f1e7ff0fb5c36829548b16bc5b3595 992 Gene3D G3DSA:3.30.460.10 673 833 9.7E-49 T 06-07-2017 CAK77_RS09310 98f1e7ff0fb5c36829548b16bc5b3595 992 Gene3D G3DSA:3.30.460.10 177 322 1.0E-44 T 06-07-2017 CAK77_RS09310 98f1e7ff0fb5c36829548b16bc5b3595 992 SUPERFAMILY SSF81301 68 322 1.96E-56 T 06-07-2017 CAK77_RS09310 98f1e7ff0fb5c36829548b16bc5b3595 992 SUPERFAMILY SSF81593 328 482 2.9E-33 T 06-07-2017 CAK77_RS09310 98f1e7ff0fb5c36829548b16bc5b3595 992 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 587 826 1.4E-64 T 06-07-2017 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 CAK77_RS09310 98f1e7ff0fb5c36829548b16bc5b3595 992 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 84 312 3.9E-35 T 06-07-2017 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 CAK77_RS09310 98f1e7ff0fb5c36829548b16bc5b3595 992 Hamap MF_00802 Glutamate-ammonia-ligase adenylyltransferase [glnE]. 80 981 16.59 T 06-07-2017 IPR023057 Glutamate-ammonia-ligase adenylyltransferase GO:0008882 CAK77_RS09310 98f1e7ff0fb5c36829548b16bc5b3595 992 Pfam PF08335 GlnD PII-uridylyltransferase 335 482 2.5E-35 T 06-07-2017 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 CAK77_RS09310 98f1e7ff0fb5c36829548b16bc5b3595 992 Pfam PF08335 GlnD PII-uridylyltransferase 848 989 1.5E-21 T 06-07-2017 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 CAK77_RS09310 98f1e7ff0fb5c36829548b16bc5b3595 992 SUPERFAMILY SSF81593 839 991 2.98E-37 T 06-07-2017 CAK77_RS09310 98f1e7ff0fb5c36829548b16bc5b3595 992 SUPERFAMILY SSF81301 559 831 2.29E-63 T 06-07-2017 CAK77_RS13500 dc0c1e06a8cbfda69596d6c754942373 321 SUPERFAMILY SSF56059 106 286 3.33E-10 T 06-07-2017 CAK77_RS02215 94228b32d120394dda822ede50280908 165 SMART SM00894 128 164 1.0E-19 T 06-07-2017 IPR008613 Excalibur calcium-binding domain CAK77_RS02215 94228b32d120394dda822ede50280908 165 Pfam PF05305 Protein of unknown function (DUF732) 8 96 2.4E-12 T 06-07-2017 IPR007969 Domain of unknown function DUF732 CAK77_RS02215 94228b32d120394dda822ede50280908 165 Pfam PF05901 Excalibur calcium-binding domain 129 164 4.7E-14 T 06-07-2017 IPR008613 Excalibur calcium-binding domain CAK77_RS00465 e0c71aacf2d32b1e1f61d49b1adb12c3 467 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 352 460 3.3E-25 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CAK77_RS00465 e0c71aacf2d32b1e1f61d49b1adb12c3 467 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 38 48 - T 06-07-2017 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 CAK77_RS00465 e0c71aacf2d32b1e1f61d49b1adb12c3 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 2.3E-52 T 06-07-2017 CAK77_RS00465 e0c71aacf2d32b1e1f61d49b1adb12c3 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 309 316 2.3E-52 T 06-07-2017 CAK77_RS00465 e0c71aacf2d32b1e1f61d49b1adb12c3 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 348 369 2.3E-52 T 06-07-2017 CAK77_RS00465 e0c71aacf2d32b1e1f61d49b1adb12c3 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 413 428 2.3E-52 T 06-07-2017 CAK77_RS00465 e0c71aacf2d32b1e1f61d49b1adb12c3 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 181 206 2.3E-52 T 06-07-2017 CAK77_RS00465 e0c71aacf2d32b1e1f61d49b1adb12c3 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 266 280 2.3E-52 T 06-07-2017 CAK77_RS00465 e0c71aacf2d32b1e1f61d49b1adb12c3 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 37 52 2.3E-52 T 06-07-2017 CAK77_RS00465 e0c71aacf2d32b1e1f61d49b1adb12c3 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 145 154 2.3E-52 T 06-07-2017 CAK77_RS00465 e0c71aacf2d32b1e1f61d49b1adb12c3 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 5.7E-25 T 06-07-2017 CAK77_RS00465 e0c71aacf2d32b1e1f61d49b1adb12c3 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 142 160 5.7E-25 T 06-07-2017 CAK77_RS00465 e0c71aacf2d32b1e1f61d49b1adb12c3 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 181 199 5.7E-25 T 06-07-2017 CAK77_RS00465 e0c71aacf2d32b1e1f61d49b1adb12c3 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 294 316 5.7E-25 T 06-07-2017 CAK77_RS00465 e0c71aacf2d32b1e1f61d49b1adb12c3 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 265 281 5.7E-25 T 06-07-2017 CAK77_RS00465 e0c71aacf2d32b1e1f61d49b1adb12c3 467 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 326 5.0E-45 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS00465 e0c71aacf2d32b1e1f61d49b1adb12c3 467 Gene3D G3DSA:3.50.50.60 1 144 5.1E-23 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS00465 e0c71aacf2d32b1e1f61d49b1adb12c3 467 Gene3D G3DSA:3.50.50.60 145 337 3.6E-46 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS00465 e0c71aacf2d32b1e1f61d49b1adb12c3 467 Gene3D G3DSA:3.30.390.30 345 463 7.0E-36 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CAK77_RS00465 e0c71aacf2d32b1e1f61d49b1adb12c3 467 SUPERFAMILY SSF55424 349 463 2.75E-30 T 06-07-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CAK77_RS00465 e0c71aacf2d32b1e1f61d49b1adb12c3 467 PIRSF PIRSF000350 1 448 6.8E-77 T 06-07-2017 CAK77_RS00465 e0c71aacf2d32b1e1f61d49b1adb12c3 467 SUPERFAMILY SSF51905 1 383 2.49E-40 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS00465 e0c71aacf2d32b1e1f61d49b1adb12c3 467 TIGRFAM TIGR03452 mycothione_red: mycothione reductase 2 465 5.6E-208 T 06-07-2017 IPR017817 Mycothione reductase MetaCyc: PWY-6421 CAK77_RS04930 9bd45f45b4d54982d77b331b10ffe9e0 414 Gene3D G3DSA:1.25.40.10 199 312 1.1E-8 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK77_RS08875 b893db5555cba20b6dbc50e50d817f0c 528 Pfam PF00005 ABC transporter 355 480 6.8E-18 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK77_RS08875 b893db5555cba20b6dbc50e50d817f0c 528 Pfam PF00005 ABC transporter 32 170 6.9E-23 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK77_RS08875 b893db5555cba20b6dbc50e50d817f0c 528 Gene3D G3DSA:3.40.50.300 355 514 6.5E-32 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS08875 b893db5555cba20b6dbc50e50d817f0c 528 SUPERFAMILY SSF52540 17 219 1.08E-45 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS08875 b893db5555cba20b6dbc50e50d817f0c 528 SMART SM00382 359 525 1.1E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS08875 b893db5555cba20b6dbc50e50d817f0c 528 SMART SM00382 29 330 4.2E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS08875 b893db5555cba20b6dbc50e50d817f0c 528 Gene3D G3DSA:3.40.50.300 10 244 1.7E-45 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS08875 b893db5555cba20b6dbc50e50d817f0c 528 SUPERFAMILY SSF52540 354 512 4.91E-34 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS08495 b424ac1ae9b05dac4bbaa0726103d972 258 Pfam PF04452 RNA methyltransferase 20 243 1.5E-58 T 06-07-2017 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CAK77_RS08495 b424ac1ae9b05dac4bbaa0726103d972 258 SUPERFAMILY SSF75217 77 250 2.62E-41 T 06-07-2017 IPR029028 Alpha/beta knot methyltransferases CAK77_RS08495 b424ac1ae9b05dac4bbaa0726103d972 258 PIRSF PIRSF015601 3 250 8.7E-47 T 06-07-2017 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CAK77_RS08495 b424ac1ae9b05dac4bbaa0726103d972 258 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 16 246 1.0E-35 T 06-07-2017 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CAK77_RS08495 b424ac1ae9b05dac4bbaa0726103d972 258 SUPERFAMILY SSF88697 6 71 7.95E-13 T 06-07-2017 IPR015947 PUA-like domain CAK77_RS08495 b424ac1ae9b05dac4bbaa0726103d972 258 Gene3D G3DSA:3.40.1280.10 6 251 2.7E-67 T 06-07-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CAK77_RS22220 1537331f59a3b503fa9666aa3bb8631d 446 Gene3D G3DSA:1.10.630.10 19 437 4.3E-106 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS22220 1537331f59a3b503fa9666aa3bb8631d 446 SUPERFAMILY SSF48264 120 437 5.76E-83 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS22220 1537331f59a3b503fa9666aa3bb8631d 446 SUPERFAMILY SSF48264 38 88 5.76E-83 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS22220 1537331f59a3b503fa9666aa3bb8631d 446 Pfam PF00067 Cytochrome P450 218 307 6.2E-7 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS22220 1537331f59a3b503fa9666aa3bb8631d 446 Pfam PF00067 Cytochrome P450 314 410 3.6E-18 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS22220 1537331f59a3b503fa9666aa3bb8631d 446 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 382 391 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CAK77_RS22220 1537331f59a3b503fa9666aa3bb8631d 446 PRINTS PR00359 B-class P450 signature 380 389 3.5E-41 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS22220 1537331f59a3b503fa9666aa3bb8631d 446 PRINTS PR00359 B-class P450 signature 188 203 3.5E-41 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS22220 1537331f59a3b503fa9666aa3bb8631d 446 PRINTS PR00359 B-class P450 signature 125 136 3.5E-41 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS22220 1537331f59a3b503fa9666aa3bb8631d 446 PRINTS PR00359 B-class P450 signature 313 324 3.5E-41 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS22220 1537331f59a3b503fa9666aa3bb8631d 446 PRINTS PR00359 B-class P450 signature 330 357 3.5E-41 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS22220 1537331f59a3b503fa9666aa3bb8631d 446 PRINTS PR00359 B-class P450 signature 389 400 3.5E-41 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS22220 1537331f59a3b503fa9666aa3bb8631d 446 PRINTS PR00359 B-class P450 signature 171 187 3.5E-41 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS22220 1537331f59a3b503fa9666aa3bb8631d 446 PRINTS PR00359 B-class P450 signature 358 373 3.5E-41 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS04380 cfe71c43bd07318d09b8f262834d6e16 181 Gene3D G3DSA:3.30.70.640 27 180 1.1E-62 T 06-07-2017 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 CAK77_RS04380 cfe71c43bd07318d09b8f262834d6e16 181 Pfam PF01967 MoaC family 38 173 7.5E-50 T 06-07-2017 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 CAK77_RS04380 cfe71c43bd07318d09b8f262834d6e16 181 SUPERFAMILY SSF55040 34 178 3.14E-55 T 06-07-2017 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 CAK77_RS04380 cfe71c43bd07318d09b8f262834d6e16 181 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 27 175 6.2E-59 T 06-07-2017 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 Reactome: R-HSA-947581 CAK77_RS04380 cfe71c43bd07318d09b8f262834d6e16 181 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase accessory protein [moaC]. 25 181 34.518 T 06-07-2017 IPR023046 Molybdenum cofactor biosynthesis C, bacterial-type Reactome: R-HSA-947581 CAK77_RS04310 2d1c783688194d313952a06fdf43bb17 402 ProSitePatterns PS00737 Thiolases signature 2. 348 364 - T 06-07-2017 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CAK77_RS04310 2d1c783688194d313952a06fdf43bb17 402 Gene3D G3DSA:3.40.47.10 4 126 2.4E-56 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS04310 2d1c783688194d313952a06fdf43bb17 402 Gene3D G3DSA:3.40.47.10 185 285 2.4E-56 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS04310 2d1c783688194d313952a06fdf43bb17 402 PIRSF PIRSF000429 1 402 4.3E-111 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 CAK77_RS04310 2d1c783688194d313952a06fdf43bb17 402 Gene3D G3DSA:3.40.47.10 286 401 2.3E-57 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS04310 2d1c783688194d313952a06fdf43bb17 402 Gene3D G3DSA:3.40.47.10 146 184 2.3E-57 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS04310 2d1c783688194d313952a06fdf43bb17 402 Pfam PF02803 Thiolase, C-terminal domain 280 401 3.2E-46 T 06-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CAK77_RS04310 2d1c783688194d313952a06fdf43bb17 402 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 87 105 - T 06-07-2017 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 CAK77_RS04310 2d1c783688194d313952a06fdf43bb17 402 ProSitePatterns PS00099 Thiolases active site. 383 396 - T 06-07-2017 IPR020610 Thiolase, active site GO:0008152|GO:0016747 CAK77_RS04310 2d1c783688194d313952a06fdf43bb17 402 SUPERFAMILY SSF53901 280 401 1.4E-44 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS04310 2d1c783688194d313952a06fdf43bb17 402 Pfam PF00108 Thiolase, N-terminal domain 5 225 7.1E-43 T 06-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CAK77_RS04310 2d1c783688194d313952a06fdf43bb17 402 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 400 6.2E-130 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 CAK77_RS04310 2d1c783688194d313952a06fdf43bb17 402 SUPERFAMILY SSF53901 1 273 1.68E-62 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS09595 30ecf2ead5bffe62fd88b5e3754f6600 381 SUPERFAMILY SSF54001 267 380 5.89E-36 T 06-07-2017 CAK77_RS09595 30ecf2ead5bffe62fd88b5e3754f6600 381 Pfam PF00877 NlpC/P60 family 281 364 4.8E-23 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain CAK77_RS09595 30ecf2ead5bffe62fd88b5e3754f6600 381 Gene3D G3DSA:3.90.1720.10 267 380 4.3E-38 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain CAK77_RS11245 09710c5348e52728a04abc185bdfd216 483 Gene3D G3DSA:3.40.630.10 419 480 1.6E-46 T 06-07-2017 CAK77_RS11245 09710c5348e52728a04abc185bdfd216 483 Gene3D G3DSA:3.40.630.10 40 244 1.6E-46 T 06-07-2017 CAK77_RS11245 09710c5348e52728a04abc185bdfd216 483 Pfam PF07687 Peptidase dimerisation domain 231 359 4.9E-16 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAK77_RS11245 09710c5348e52728a04abc185bdfd216 483 Pfam PF01546 Peptidase family M20/M25/M40 113 477 2.0E-32 T 06-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CAK77_RS11245 09710c5348e52728a04abc185bdfd216 483 Gene3D G3DSA:3.30.70.360 245 282 1.2E-13 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAK77_RS11245 09710c5348e52728a04abc185bdfd216 483 Gene3D G3DSA:3.30.70.360 327 360 1.2E-13 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAK77_RS11245 09710c5348e52728a04abc185bdfd216 483 SUPERFAMILY SSF53187 36 233 1.86E-46 T 06-07-2017 CAK77_RS11245 09710c5348e52728a04abc185bdfd216 483 SUPERFAMILY SSF53187 394 480 1.86E-46 T 06-07-2017 CAK77_RS11245 09710c5348e52728a04abc185bdfd216 483 SUPERFAMILY SSF55031 328 359 4.71E-6 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAK77_RS11245 09710c5348e52728a04abc185bdfd216 483 SUPERFAMILY SSF55031 238 277 4.71E-6 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAK77_RS11245 09710c5348e52728a04abc185bdfd216 483 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 112 121 - T 06-07-2017 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CAK77_RS17655 04e66cba954103071465aede104d2a2e 391 Pfam PF00581 Rhodanese-like domain 289 382 1.9E-13 T 06-07-2017 IPR001763 Rhodanese-like domain CAK77_RS17655 04e66cba954103071465aede104d2a2e 391 Gene3D G3DSA:3.40.250.10 286 386 8.0E-27 T 06-07-2017 IPR001763 Rhodanese-like domain CAK77_RS17655 04e66cba954103071465aede104d2a2e 391 SMART SM00450 289 386 2.1E-26 T 06-07-2017 IPR001763 Rhodanese-like domain CAK77_RS17655 04e66cba954103071465aede104d2a2e 391 SUPERFAMILY SSF69572 9 358 5.89E-94 T 06-07-2017 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CAK77_RS17655 04e66cba954103071465aede104d2a2e 391 Pfam PF00899 ThiF family 22 257 3.0E-59 T 06-07-2017 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CAK77_RS17655 04e66cba954103071465aede104d2a2e 391 Gene3D G3DSA:3.40.50.720 14 258 4.0E-70 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS02830 10824656bba9a4c16730a1bea82506ee 500 Pfam PF01336 OB-fold nucleic acid binding domain 64 139 1.3E-8 T 06-07-2017 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CAK77_RS02830 10824656bba9a4c16730a1bea82506ee 500 PRINTS PR00982 Lysyl-tRNA synthetase signature 382 398 3.4E-32 T 06-07-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CAK77_RS02830 10824656bba9a4c16730a1bea82506ee 500 PRINTS PR00982 Lysyl-tRNA synthetase signature 193 203 3.4E-32 T 06-07-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CAK77_RS02830 10824656bba9a4c16730a1bea82506ee 500 PRINTS PR00982 Lysyl-tRNA synthetase signature 256 273 3.4E-32 T 06-07-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CAK77_RS02830 10824656bba9a4c16730a1bea82506ee 500 PRINTS PR00982 Lysyl-tRNA synthetase signature 209 225 3.4E-32 T 06-07-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CAK77_RS02830 10824656bba9a4c16730a1bea82506ee 500 PRINTS PR00982 Lysyl-tRNA synthetase signature 238 251 3.4E-32 T 06-07-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CAK77_RS02830 10824656bba9a4c16730a1bea82506ee 500 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 16 499 35.081 T 06-07-2017 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CAK77_RS02830 10824656bba9a4c16730a1bea82506ee 500 SUPERFAMILY SSF50249 8 149 1.54E-34 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS02830 10824656bba9a4c16730a1bea82506ee 500 SUPERFAMILY SSF55681 156 497 1.51E-95 T 06-07-2017 CAK77_RS02830 10824656bba9a4c16730a1bea82506ee 500 Gene3D G3DSA:3.30.930.10 152 494 1.4E-97 T 06-07-2017 CAK77_RS02830 10824656bba9a4c16730a1bea82506ee 500 Gene3D G3DSA:2.40.50.140 11 149 1.1E-45 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS02830 10824656bba9a4c16730a1bea82506ee 500 Pfam PF00152 tRNA synthetases class II (D, K and N) 156 495 2.9E-65 T 06-07-2017 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK77_RS02830 10824656bba9a4c16730a1bea82506ee 500 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 12 498 1.6E-136 T 06-07-2017 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CAK77_RS14635 9fc03c6319fca00336603518077dcb64 246 Pfam PF01177 Asp/Glu/Hydantoin racemase 3 207 3.6E-14 T 06-07-2017 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK77_RS23880 84ca6c24101513a54e225bb1aa17d1f3 419 Gene3D G3DSA:1.20.1250.20 232 415 1.5E-18 T 06-07-2017 CAK77_RS23880 84ca6c24101513a54e225bb1aa17d1f3 419 Pfam PF07690 Major Facilitator Superfamily 236 411 4.4E-16 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK77_RS23880 84ca6c24101513a54e225bb1aa17d1f3 419 SUPERFAMILY SSF103473 24 415 8.24E-41 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK77_RS23880 84ca6c24101513a54e225bb1aa17d1f3 419 Gene3D G3DSA:1.20.1250.20 23 210 6.8E-16 T 06-07-2017 CAK77_RS09170 084d877107e7243264a430150efc3d72 185 Pfam PF12079 Protein of unknown function (DUF3558) 13 181 2.1E-24 T 06-07-2017 IPR024520 Protein of unknown function DUF3558 CAK77_RS10370 69ddd017af77e7e30b4d14d870555e22 135 SUPERFAMILY SSF52172 6 130 7.47E-9 T 06-07-2017 IPR011006 CheY-like superfamily CAK77_RS10370 69ddd017af77e7e30b4d14d870555e22 135 Gene3D G3DSA:3.40.50.2300 3 131 1.1E-11 T 06-07-2017 CAK77_RS15125 c07e7ebbc66c0f743792fc10023034a0 224 Hamap MF_00015 LexA repressor [lexA]. 13 224 32.952 T 06-07-2017 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 CAK77_RS15125 c07e7ebbc66c0f743792fc10023034a0 224 Pfam PF01726 LexA DNA binding domain 13 75 1.2E-28 T 06-07-2017 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 CAK77_RS15125 c07e7ebbc66c0f743792fc10023034a0 224 SUPERFAMILY SSF51306 103 222 3.14E-35 T 06-07-2017 IPR015927 Peptidase S24/S26A/S26B/S26C CAK77_RS15125 c07e7ebbc66c0f743792fc10023034a0 224 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 140 150 7.2E-11 T 06-07-2017 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CAK77_RS15125 c07e7ebbc66c0f743792fc10023034a0 224 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 179 191 7.2E-11 T 06-07-2017 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CAK77_RS15125 c07e7ebbc66c0f743792fc10023034a0 224 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 151 162 7.2E-11 T 06-07-2017 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CAK77_RS15125 c07e7ebbc66c0f743792fc10023034a0 224 SUPERFAMILY SSF46785 13 79 1.3E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS15125 c07e7ebbc66c0f743792fc10023034a0 224 Pfam PF00717 Peptidase S24-like 143 210 2.0E-14 T 06-07-2017 IPR019759 Peptidase S24/S26A/S26B CAK77_RS15125 c07e7ebbc66c0f743792fc10023034a0 224 Gene3D G3DSA:1.10.10.10 13 79 1.1E-31 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS15125 c07e7ebbc66c0f743792fc10023034a0 224 Gene3D G3DSA:2.10.109.10 105 223 1.6E-43 T 06-07-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain CAK77_RS15125 c07e7ebbc66c0f743792fc10023034a0 224 TIGRFAM TIGR00498 lexA: repressor LexA 13 224 2.5E-80 T 06-07-2017 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 CAK77_RS24320 a8b338288707b4415a25f3450a26ce55 76 PRINTS PR00352 3Fe-4S ferredoxin signature 57 69 7.6E-6 T 06-07-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 CAK77_RS24320 a8b338288707b4415a25f3450a26ce55 76 PRINTS PR00352 3Fe-4S ferredoxin signature 14 25 7.6E-6 T 06-07-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 CAK77_RS24320 a8b338288707b4415a25f3450a26ce55 76 PRINTS PR00352 3Fe-4S ferredoxin signature 25 35 7.6E-6 T 06-07-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 CAK77_RS24320 a8b338288707b4415a25f3450a26ce55 76 Gene3D G3DSA:3.30.70.20 11 72 8.2E-14 T 06-07-2017 CAK77_RS24320 a8b338288707b4415a25f3450a26ce55 76 Pfam PF13459 4Fe-4S single cluster domain 12 71 3.9E-14 T 06-07-2017 CAK77_RS24320 a8b338288707b4415a25f3450a26ce55 76 SUPERFAMILY SSF54862 12 71 8.13E-10 T 06-07-2017 CAK77_RS12445 b44fe2b7bc579acbb4195c4843fb4f1a 231 SUPERFAMILY SSF53056 33 230 5.36E-43 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CAK77_RS12445 b44fe2b7bc579acbb4195c4843fb4f1a 231 Pfam PF00484 Carbonic anhydrase 75 225 9.2E-33 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CAK77_RS12445 b44fe2b7bc579acbb4195c4843fb4f1a 231 Gene3D G3DSA:3.40.1050.10 22 230 8.4E-47 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CAK77_RS12445 b44fe2b7bc579acbb4195c4843fb4f1a 231 SMART SM00947 68 230 1.0E-36 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CAK77_RS15955 d7ae58165a778cefe5279d10e87fc3f4 121 Pfam PF13564 DoxX-like family 7 115 1.2E-21 T 06-07-2017 IPR032808 DoxX family CAK77_RS23430 0a89c9fbc9a1fef703a98550fcf2cd28 136 Pfam PF05423 Mycobacterium membrane protein 1 136 1.5E-53 T 06-07-2017 IPR008693 Transport accessory protein MmpS CAK77_RS15555 a4d673b2c5c72585fc6800406de6b5c2 331 Gene3D G3DSA:3.90.1640.10 28 208 1.7E-23 T 06-07-2017 CAK77_RS15555 a4d673b2c5c72585fc6800406de6b5c2 331 SUPERFAMILY SSF64182 29 330 1.7E-52 T 06-07-2017 CAK77_RS15555 a4d673b2c5c72585fc6800406de6b5c2 331 Pfam PF01368 DHH family 29 171 5.1E-14 T 06-07-2017 IPR001667 DDH domain CAK77_RS15555 a4d673b2c5c72585fc6800406de6b5c2 331 Pfam PF02272 DHHA1 domain 270 323 1.4E-6 T 06-07-2017 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 CAK77_RS16350 92e5c08a66b4f8b97a65237e6a2001a0 315 PIRSF PIRSF005303 3 312 1.8E-85 T 06-07-2017 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 CAK77_RS16350 92e5c08a66b4f8b97a65237e6a2001a0 315 Gene3D G3DSA:3.30.1330.10 4 144 1.0E-39 T 06-07-2017 IPR016188 PurM-like, N-terminal domain CAK77_RS16350 92e5c08a66b4f8b97a65237e6a2001a0 315 Gene3D G3DSA:3.90.650.10 150 312 1.4E-39 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain CAK77_RS16350 92e5c08a66b4f8b97a65237e6a2001a0 315 Pfam PF00586 AIR synthase related protein, N-terminal domain 32 141 6.0E-17 T 06-07-2017 IPR016188 PurM-like, N-terminal domain CAK77_RS16350 92e5c08a66b4f8b97a65237e6a2001a0 315 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 8 312 4.0E-79 T 06-07-2017 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 CAK77_RS16350 92e5c08a66b4f8b97a65237e6a2001a0 315 SUPERFAMILY SSF55326 4 141 3.49E-31 T 06-07-2017 CAK77_RS16350 92e5c08a66b4f8b97a65237e6a2001a0 315 SUPERFAMILY SSF56042 148 297 8.16E-28 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain CAK77_RS16350 92e5c08a66b4f8b97a65237e6a2001a0 315 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 7 309 27.359 T 06-07-2017 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 CAK77_RS22295 2a2c28fc4aae2091b1cef0d980b7ebf7 307 SUPERFAMILY SSF47240 9 234 2.01E-45 T 06-07-2017 IPR009078 Ferritin-like superfamily CAK77_RS22295 2a2c28fc4aae2091b1cef0d980b7ebf7 307 Gene3D G3DSA:1.20.1260.10 40 95 9.5E-5 T 06-07-2017 IPR012347 Ferritin-related CAK77_RS04390 2799f1b93ae88fa1340b331d49b3dd2a 142 Gene3D G3DSA:3.90.1170.40 4 140 6.2E-41 T 06-07-2017 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CAK77_RS04390 2799f1b93ae88fa1340b331d49b3dd2a 142 Pfam PF02391 MoaE protein 10 121 9.8E-33 T 06-07-2017 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CAK77_RS04390 2799f1b93ae88fa1340b331d49b3dd2a 142 SUPERFAMILY SSF54690 10 140 1.05E-36 T 06-07-2017 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CAK77_RS16440 7140210cc556f3ecb99352998dd0a3b8 219 SUPERFAMILY SSF46689 12 80 6.67E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS16440 7140210cc556f3ecb99352998dd0a3b8 219 Gene3D G3DSA:1.10.357.10 2 194 6.3E-22 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS16440 7140210cc556f3ecb99352998dd0a3b8 219 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 68 1.1E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS12750 9e1715a54139539c3b993b4967f9f412 254 Gene3D G3DSA:3.20.20.370 63 253 1.6E-36 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAK77_RS12750 9e1715a54139539c3b993b4967f9f412 254 SUPERFAMILY SSF88713 58 253 2.83E-40 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CAK77_RS12750 9e1715a54139539c3b993b4967f9f412 254 Pfam PF01522 Polysaccharide deacetylase 60 183 9.5E-24 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAK77_RS10710 f5d7978e4a4d5d961d5135069b3399ff 208 SUPERFAMILY SSF63965 2 204 4.45E-69 T 06-07-2017 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 CAK77_RS10710 f5d7978e4a4d5d961d5135069b3399ff 208 Gene3D G3DSA:3.40.50.10230 3 204 2.5E-74 T 06-07-2017 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 CAK77_RS10710 f5d7978e4a4d5d961d5135069b3399ff 208 Pfam PF02570 Precorrin-8X methylmutase 10 204 2.4E-67 T 06-07-2017 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 CAK77_RS19655 c87095a926fcf8340d2497caa42f2f63 199 Gene3D G3DSA:1.10.357.10 18 194 6.4E-25 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS19655 c87095a926fcf8340d2497caa42f2f63 199 SUPERFAMILY SSF46689 18 80 2.87E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS19655 c87095a926fcf8340d2497caa42f2f63 199 SUPERFAMILY SSF48498 89 195 4.85E-16 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS19655 c87095a926fcf8340d2497caa42f2f63 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 68 1.1E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS05195 7e9e6987ae93c12a4a0eacc60daace5f 409 Pfam PF01566 Natural resistance-associated macrophage protein 33 381 3.6E-113 T 06-07-2017 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CAK77_RS05195 7e9e6987ae93c12a4a0eacc60daace5f 409 PRINTS PR00447 Natural resistance-associated macrophage protein signature 120 139 4.0E-27 T 06-07-2017 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CAK77_RS05195 7e9e6987ae93c12a4a0eacc60daace5f 409 PRINTS PR00447 Natural resistance-associated macrophage protein signature 195 218 4.0E-27 T 06-07-2017 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CAK77_RS05195 7e9e6987ae93c12a4a0eacc60daace5f 409 PRINTS PR00447 Natural resistance-associated macrophage protein signature 297 316 4.0E-27 T 06-07-2017 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CAK77_RS05195 7e9e6987ae93c12a4a0eacc60daace5f 409 PRINTS PR00447 Natural resistance-associated macrophage protein signature 92 118 4.0E-27 T 06-07-2017 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CAK77_RS05195 7e9e6987ae93c12a4a0eacc60daace5f 409 PRINTS PR00447 Natural resistance-associated macrophage protein signature 146 167 4.0E-27 T 06-07-2017 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CAK77_RS05195 7e9e6987ae93c12a4a0eacc60daace5f 409 Hamap MF_00221 Divalent metal cation transporter MntH [mntH]. 5 407 33.718 T 06-07-2017 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CAK77_RS05195 7e9e6987ae93c12a4a0eacc60daace5f 409 TIGRFAM TIGR01197 nramp: metal ion transporter, metal ion (Mn2+/Fe2+) transporter (Nramp) family 15 375 3.1E-84 T 06-07-2017 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CAK77_RS04210 52e64e8c9119a077e71e309dd5f0e077 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 4.9E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS04210 52e64e8c9119a077e71e309dd5f0e077 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 4.9E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS04210 52e64e8c9119a077e71e309dd5f0e077 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 4.9E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS04210 52e64e8c9119a077e71e309dd5f0e077 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 4.9E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS04210 52e64e8c9119a077e71e309dd5f0e077 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 4.9E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS04210 52e64e8c9119a077e71e309dd5f0e077 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 4.9E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS04210 52e64e8c9119a077e71e309dd5f0e077 247 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 246 6.1E-65 T 06-07-2017 CAK77_RS04210 52e64e8c9119a077e71e309dd5f0e077 247 SUPERFAMILY SSF51735 6 247 1.13E-78 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS04210 52e64e8c9119a077e71e309dd5f0e077 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 2.8E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS04210 52e64e8c9119a077e71e309dd5f0e077 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 2.8E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS04210 52e64e8c9119a077e71e309dd5f0e077 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 2.8E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS04210 52e64e8c9119a077e71e309dd5f0e077 247 Gene3D G3DSA:3.40.50.720 3 247 9.0E-82 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS04210 52e64e8c9119a077e71e309dd5f0e077 247 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK77_RS22640 3a4daad537d929a98e2033c1c088a60f 168 TIGRFAM TIGR04338 HEXXH_Rv0185: putative metallohydrolase, TIGR04338 family 8 166 3.2E-66 T 06-07-2017 IPR027595 Conserved hypothetical protein CHP04338 CAK77_RS03425 c33dc4112dc89eba73b456341944e67c 502 Pfam PF00501 AMP-binding enzyme 15 396 1.6E-63 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK77_RS03425 c33dc4112dc89eba73b456341944e67c 502 Gene3D G3DSA:3.30.300.30 392 493 1.0E-15 T 06-07-2017 CAK77_RS03425 c33dc4112dc89eba73b456341944e67c 502 SUPERFAMILY SSF56801 6 496 3.01E-100 T 06-07-2017 CAK77_RS03425 c33dc4112dc89eba73b456341944e67c 502 Gene3D G3DSA:3.40.50.980 8 149 1.4E-26 T 06-07-2017 CAK77_RS03425 c33dc4112dc89eba73b456341944e67c 502 Gene3D G3DSA:3.40.50.980 150 310 1.5E-21 T 06-07-2017 CAK77_RS03425 c33dc4112dc89eba73b456341944e67c 502 Pfam PF13193 AMP-binding enzyme C-terminal domain 406 485 5.0E-9 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAK77_RS03425 c33dc4112dc89eba73b456341944e67c 502 ProSitePatterns PS00455 Putative AMP-binding domain signature. 142 153 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK77_RS03425 c33dc4112dc89eba73b456341944e67c 502 Gene3D G3DSA:2.30.38.10 312 390 1.0E-16 T 06-07-2017 CAK77_RS09765 39b4c4f63bcd4e251512117e672acae7 309 Pfam PF08478 POTRA domain, FtsQ-type 120 187 2.5E-14 T 06-07-2017 IPR013685 Polypeptide-transport-associated, FtsQ-type CAK77_RS09765 39b4c4f63bcd4e251512117e672acae7 309 Pfam PF03799 Cell division protein FtsQ 191 293 1.3E-9 T 06-07-2017 IPR005548 Cell division protein FtsQ/DivIB CAK77_RS09765 39b4c4f63bcd4e251512117e672acae7 309 Hamap MF_00911 Cell division protein FtsQ [ftsQ]. 89 309 16.965 T 06-07-2017 IPR026579 Cell division protein FtsQ GO:0090529 CAK77_RS21655 2cd38699ec40b2a26c1cfcbd3d5b9fea 309 SUPERFAMILY SSF56436 21 307 1.53E-87 T 06-07-2017 IPR016187 C-type lectin fold CAK77_RS21655 2cd38699ec40b2a26c1cfcbd3d5b9fea 309 Pfam PF03781 Sulfatase-modifying factor enzyme 1 21 305 1.0E-85 T 06-07-2017 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 CAK77_RS21655 2cd38699ec40b2a26c1cfcbd3d5b9fea 309 Gene3D G3DSA:3.90.1580.10 16 307 4.0E-90 T 06-07-2017 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 CAK77_RS23100 89da710dbc0449720e3fafef56053c7f 297 SMART SM00530 14 86 2.1E-5 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAK77_RS23100 89da710dbc0449720e3fafef56053c7f 297 SUPERFAMILY SSF47413 8 84 1.79E-5 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK77_RS23100 89da710dbc0449720e3fafef56053c7f 297 Gene3D G3DSA:1.10.260.40 5 85 7.8E-18 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK77_RS23100 89da710dbc0449720e3fafef56053c7f 297 Pfam PF13560 Helix-turn-helix domain 10 88 2.4E-15 T 06-07-2017 CAK77_RS22680 42d3722b5c5d32103ee8285611e58498 202 Gene3D G3DSA:1.20.1440.20 18 190 6.1E-59 T 06-07-2017 IPR023353 LemA-like domain CAK77_RS22680 42d3722b5c5d32103ee8285611e58498 202 SUPERFAMILY SSF140478 29 181 1.05E-49 T 06-07-2017 IPR023353 LemA-like domain CAK77_RS22680 42d3722b5c5d32103ee8285611e58498 202 Pfam PF04011 LemA family 11 190 4.3E-63 T 06-07-2017 IPR007156 LemA CAK77_RS07725 ca914e80d054ef65adb72b8c5024b3e8 208 Gene3D G3DSA:3.30.420.10 6 181 1.1E-67 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAK77_RS07725 ca914e80d054ef65adb72b8c5024b3e8 208 Hamap MF_00045 Oligoribonuclease [orn]. 3 183 38.338 T 06-07-2017 IPR022894 Oligoribonuclease GO:0016788 CAK77_RS07725 ca914e80d054ef65adb72b8c5024b3e8 208 SUPERFAMILY SSF53098 5 182 3.87E-44 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAK77_RS07725 ca914e80d054ef65adb72b8c5024b3e8 208 SMART SM00479 7 182 2.7E-31 T 06-07-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III CAK77_RS07725 ca914e80d054ef65adb72b8c5024b3e8 208 Pfam PF00929 Exonuclease 9 172 1.7E-31 T 06-07-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III CAK77_RS23575 a862c1a95de5080f1c03b4c42362327a 473 Gene3D G3DSA:3.50.50.60 5 38 6.8E-14 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS23575 a862c1a95de5080f1c03b4c42362327a 473 Pfam PF13450 NAD(P)-binding Rossmann-like domain 6 58 3.4E-11 T 06-07-2017 CAK77_RS23575 a862c1a95de5080f1c03b4c42362327a 473 SUPERFAMILY SSF51905 433 465 1.41E-27 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS23575 a862c1a95de5080f1c03b4c42362327a 473 SUPERFAMILY SSF51905 4 301 1.41E-27 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS23575 a862c1a95de5080f1c03b4c42362327a 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 4.4E-5 T 06-07-2017 CAK77_RS23575 a862c1a95de5080f1c03b4c42362327a 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 289 310 4.4E-5 T 06-07-2017 CAK77_RS23575 a862c1a95de5080f1c03b4c42362327a 473 Gene3D G3DSA:3.50.50.60 195 280 7.2E-6 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS23575 a862c1a95de5080f1c03b4c42362327a 473 Gene3D G3DSA:3.50.50.60 436 469 7.2E-6 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS04720 0a0471f6abdb2bfbec0c5b021992684b 366 Gene3D G3DSA:3.60.15.10 80 364 6.8E-102 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK77_RS04720 0a0471f6abdb2bfbec0c5b021992684b 366 Pfam PF12706 Beta-lactamase superfamily domain 117 314 8.9E-48 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK77_RS04720 0a0471f6abdb2bfbec0c5b021992684b 366 PIRSF PIRSF038896 13 355 1.6E-100 T 06-07-2017 IPR024884 N-acyl-phosphatidylethanolamine-hydrolysing phospholipase D GO:0008270|GO:0070290 Reactome: R-HSA-2466712 CAK77_RS04720 0a0471f6abdb2bfbec0c5b021992684b 366 SUPERFAMILY SSF56281 204 352 1.02E-35 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK77_RS04720 0a0471f6abdb2bfbec0c5b021992684b 366 SUPERFAMILY SSF56281 102 176 1.02E-35 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK77_RS17865 ce3576631901c621d52314cef8a3ad4f 212 SUPERFAMILY SSF52540 3 200 2.08E-32 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS17865 ce3576631901c621d52314cef8a3ad4f 212 Hamap MF_00165 Thymidylate kinase [tmk]. 3 212 13.032 T 06-07-2017 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 CAK77_RS17865 ce3576631901c621d52314cef8a3ad4f 212 Gene3D G3DSA:3.40.50.300 4 208 4.3E-45 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS17865 ce3576631901c621d52314cef8a3ad4f 212 Pfam PF02223 Thymidylate kinase 7 188 1.1E-22 T 06-07-2017 CAK77_RS17480 951bec6c4c40af762e4b6ec95e9bdd4e 660 Gene3D G3DSA:2.30.38.10 481 551 1.0E-14 T 06-07-2017 CAK77_RS17480 951bec6c4c40af762e4b6ec95e9bdd4e 660 Gene3D G3DSA:3.40.50.980 339 472 5.8E-34 T 06-07-2017 CAK77_RS17480 951bec6c4c40af762e4b6ec95e9bdd4e 660 Pfam PF00501 AMP-binding enzyme 167 558 4.4E-62 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK77_RS17480 951bec6c4c40af762e4b6ec95e9bdd4e 660 Gene3D G3DSA:3.30.300.30 553 648 1.5E-26 T 06-07-2017 CAK77_RS17480 951bec6c4c40af762e4b6ec95e9bdd4e 660 Gene3D G3DSA:3.40.50.980 166 328 2.3E-16 T 06-07-2017 CAK77_RS17480 951bec6c4c40af762e4b6ec95e9bdd4e 660 Pfam PF13193 AMP-binding enzyme C-terminal domain 568 642 2.1E-15 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAK77_RS17480 951bec6c4c40af762e4b6ec95e9bdd4e 660 SUPERFAMILY SSF56801 160 651 2.09E-113 T 06-07-2017 CAK77_RS12030 21efca7a778b371bdfc6820966174ba8 148 Gene3D G3DSA:3.30.530.20 8 146 6.4E-18 T 06-07-2017 IPR023393 START-like domain CAK77_RS12030 21efca7a778b371bdfc6820966174ba8 148 SUPERFAMILY SSF55961 7 146 2.54E-18 T 06-07-2017 CAK77_RS12030 21efca7a778b371bdfc6820966174ba8 148 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 19 145 1.3E-11 T 06-07-2017 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CAK77_RS21760 c49ffa35ada8a5029bca6ae38c361f03 352 SUPERFAMILY SSF55729 116 344 6.01E-26 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS21760 c49ffa35ada8a5029bca6ae38c361f03 352 SUPERFAMILY SSF55729 24 139 1.82E-11 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS21760 c49ffa35ada8a5029bca6ae38c361f03 352 Pfam PF00583 Acetyltransferase (GNAT) family 261 339 5.2E-9 T 06-07-2017 IPR000182 GNAT domain GO:0008080 CAK77_RS21760 c49ffa35ada8a5029bca6ae38c361f03 352 Gene3D G3DSA:3.40.630.30 190 350 1.6E-26 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS21760 c49ffa35ada8a5029bca6ae38c361f03 352 Gene3D G3DSA:3.40.630.30 33 176 2.4E-14 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS02620 ede4480c82b03ac03db8ff567de02166 548 SUPERFAMILY SSF53474 27 347 9.41E-42 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS02620 ede4480c82b03ac03db8ff567de02166 548 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 327 540 3.6E-29 T 06-07-2017 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 CAK77_RS02620 ede4480c82b03ac03db8ff567de02166 548 Gene3D G3DSA:2.60.120.260 342 544 8.0E-62 T 06-07-2017 IPR008979 Galactose-binding domain-like CAK77_RS02620 ede4480c82b03ac03db8ff567de02166 548 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 40 545 2.0E-96 T 06-07-2017 IPR005674 CocE/Serine esterase GO:0016787 CAK77_RS02620 ede4480c82b03ac03db8ff567de02166 548 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 44 301 2.6E-54 T 06-07-2017 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 CAK77_RS02620 ede4480c82b03ac03db8ff567de02166 548 SMART SM00939 312 541 6.2E-52 T 06-07-2017 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 CAK77_RS02620 ede4480c82b03ac03db8ff567de02166 548 SUPERFAMILY SSF49785 341 544 2.55E-47 T 06-07-2017 IPR008979 Galactose-binding domain-like CAK77_RS02620 ede4480c82b03ac03db8ff567de02166 548 Gene3D G3DSA:3.40.50.1820 23 172 2.9E-63 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS02620 ede4480c82b03ac03db8ff567de02166 548 Gene3D G3DSA:3.40.50.1820 248 341 2.9E-63 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS02620 ede4480c82b03ac03db8ff567de02166 548 Gene3D G3DSA:1.10.3020.10 173 247 6.2E-9 T 06-07-2017 CAK77_RS24385 71542091dce861975602b431e707016c 47 ProSitePatterns PS00784 Ribosomal protein L34 signature. 5 24 - T 06-07-2017 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS24385 71542091dce861975602b431e707016c 47 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 5 47 5.9E-18 T 06-07-2017 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS24385 71542091dce861975602b431e707016c 47 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 5 23 6.0E-4 T 06-07-2017 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS24385 71542091dce861975602b431e707016c 47 Pfam PF00468 Ribosomal protein L34 5 47 9.7E-19 T 06-07-2017 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS24385 71542091dce861975602b431e707016c 47 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 4 47 15.532 T 06-07-2017 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS18865 234c6f8701c91c43124bce9d1a0de265 292 Pfam PF13828 Domain of unknown function (DUF4190) 99 154 3.8E-19 T 06-07-2017 IPR025241 Domain of unknown function DUF4190 CAK77_RS18865 234c6f8701c91c43124bce9d1a0de265 292 Pfam PF13845 Septum formation 185 277 1.1E-11 T 06-07-2017 IPR026004 Septum formation-related domain CAK77_RS19610 92eb783c8a1069a67f4d7d0871aa532d 340 Gene3D G3DSA:3.40.50.720 7 186 4.1E-58 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS19610 92eb783c8a1069a67f4d7d0871aa532d 340 Gene3D G3DSA:1.10.1040.10 187 328 1.2E-52 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAK77_RS19610 92eb783c8a1069a67f4d7d0871aa532d 340 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 183 323 9.7E-49 T 06-07-2017 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 CAK77_RS19610 92eb783c8a1069a67f4d7d0871aa532d 340 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 7 325 36.18 T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 CAK77_RS19610 92eb783c8a1069a67f4d7d0871aa532d 340 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 191 212 - T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 CAK77_RS19610 92eb783c8a1069a67f4d7d0871aa532d 340 PIRSF PIRSF000114 2 335 1.4E-105 T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 CAK77_RS19610 92eb783c8a1069a67f4d7d0871aa532d 340 SUPERFAMILY SSF48179 182 334 1.33E-49 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAK77_RS19610 92eb783c8a1069a67f4d7d0871aa532d 340 SUPERFAMILY SSF51735 8 183 3.04E-42 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS19610 92eb783c8a1069a67f4d7d0871aa532d 340 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 136 156 2.6E-44 T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 CAK77_RS19610 92eb783c8a1069a67f4d7d0871aa532d 340 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 201 225 2.6E-44 T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 CAK77_RS19610 92eb783c8a1069a67f4d7d0871aa532d 340 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 176 200 2.6E-44 T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 CAK77_RS19610 92eb783c8a1069a67f4d7d0871aa532d 340 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 241 258 2.6E-44 T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 CAK77_RS19610 92eb783c8a1069a67f4d7d0871aa532d 340 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 11 28 2.6E-44 T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 CAK77_RS19610 92eb783c8a1069a67f4d7d0871aa532d 340 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 61 88 2.6E-44 T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 CAK77_RS19610 92eb783c8a1069a67f4d7d0871aa532d 340 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 9 163 1.5E-46 T 06-07-2017 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 CAK77_RS19645 2f917ceb0cb88400047eaceb0d7ed867 327 Pfam PF11583 P-aminobenzoate N-oxygenase AurF 36 296 1.4E-32 T 06-07-2017 IPR025859 P-aminobenzoate N-oxygenase AurF CAK77_RS13085 7c4c7d0ef3365a42d359c4dac51acf18 376 SUPERFAMILY SSF53383 34 363 8.91E-67 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK77_RS13085 7c4c7d0ef3365a42d359c4dac51acf18 376 Gene3D G3DSA:3.40.640.10 63 260 1.3E-47 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK77_RS13085 7c4c7d0ef3365a42d359c4dac51acf18 376 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 230 239 - T 06-07-2017 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 CAK77_RS13085 7c4c7d0ef3365a42d359c4dac51acf18 376 Pfam PF00155 Aminotransferase class I and II 35 355 1.1E-51 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAK77_RS13085 7c4c7d0ef3365a42d359c4dac51acf18 376 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 15 367 52.538 T 06-07-2017 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 CAK77_RS13085 7c4c7d0ef3365a42d359c4dac51acf18 376 Gene3D G3DSA:3.90.1150.10 261 364 1.4E-31 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK77_RS13085 7c4c7d0ef3365a42d359c4dac51acf18 376 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 17 364 3.3E-97 T 06-07-2017 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 CAK77_RS24375 a46d120a9306abf1e6b5ba7eaa07a0df 99 SMART SM01234 5 72 2.2E-39 T 06-07-2017 IPR002696 Putative membrane protein insertion efficiency factor CAK77_RS24375 a46d120a9306abf1e6b5ba7eaa07a0df 99 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 5 73 23.841 T 06-07-2017 IPR002696 Putative membrane protein insertion efficiency factor CAK77_RS24375 a46d120a9306abf1e6b5ba7eaa07a0df 99 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 10 79 2.4E-29 T 06-07-2017 IPR002696 Putative membrane protein insertion efficiency factor CAK77_RS24375 a46d120a9306abf1e6b5ba7eaa07a0df 99 Pfam PF01809 Haemolytic domain 7 72 9.2E-29 T 06-07-2017 IPR002696 Putative membrane protein insertion efficiency factor CAK77_RS24375 a46d120a9306abf1e6b5ba7eaa07a0df 99 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 20 72 3.0E-18 T 06-07-2017 IPR002696 Putative membrane protein insertion efficiency factor CAK77_RS22980 feb946cb9f383dfd18958b120c1afa27 501 Pfam PF03972 MmgE/PrpD family 19 470 1.6E-122 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 CAK77_RS22980 feb946cb9f383dfd18958b120c1afa27 501 SUPERFAMILY SSF103378 19 480 6.15E-120 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 CAK77_RS22980 feb946cb9f383dfd18958b120c1afa27 501 Gene3D G3DSA:3.30.1330.120 282 421 8.6E-46 T 06-07-2017 CAK77_RS10235 dd5930e23602aa4272949ba8967c2e3f 363 Gene3D G3DSA:2.130.10.10 84 335 2.6E-14 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CAK77_RS10235 dd5930e23602aa4272949ba8967c2e3f 363 SUPERFAMILY SSF50969 115 360 9.42E-18 T 06-07-2017 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like CAK77_RS07160 dfdefd30c72eaf7c2a5a8a07a8992cf2 409 SUPERFAMILY SSF103473 13 394 1.05E-61 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK77_RS07160 dfdefd30c72eaf7c2a5a8a07a8992cf2 409 Pfam PF07690 Major Facilitator Superfamily 27 353 1.1E-37 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK77_RS07160 dfdefd30c72eaf7c2a5a8a07a8992cf2 409 Gene3D G3DSA:1.20.1250.20 216 392 2.7E-18 T 06-07-2017 CAK77_RS07160 dfdefd30c72eaf7c2a5a8a07a8992cf2 409 Gene3D G3DSA:1.20.1250.20 19 198 3.3E-28 T 06-07-2017 CAK77_RS13635 d651d2419ab3eb339a589775c5dd2663 257 Pfam PF05985 Ethanolamine ammonia-lyase light chain (EutC) 11 240 2.1E-75 T 06-07-2017 IPR009246 Ethanolamine ammonia-lyase light chain GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 CAK77_RS13635 d651d2419ab3eb339a589775c5dd2663 257 PIRSF PIRSF018982 2 250 9.0E-74 T 06-07-2017 IPR009246 Ethanolamine ammonia-lyase light chain GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 CAK77_RS08620 95a50b86b33943078d65d92a23f4ed0e 91 Pfam PF00550 Phosphopantetheine attachment site 21 87 2.6E-13 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS08620 95a50b86b33943078d65d92a23f4ed0e 91 Gene3D G3DSA:1.10.1200.10 15 90 3.3E-16 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS08620 95a50b86b33943078d65d92a23f4ed0e 91 SUPERFAMILY SSF47336 16 90 1.96E-15 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS19375 6b22a055109bc578ad490ac8fd30312c 286 Gene3D G3DSA:3.40.50.150 5 286 1.7E-87 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS19375 6b22a055109bc578ad490ac8fd30312c 286 Pfam PF02353 Mycolic acid cyclopropane synthetase 3 282 1.3E-115 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS19375 6b22a055109bc578ad490ac8fd30312c 286 SUPERFAMILY SSF53335 12 286 1.1E-76 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS19375 6b22a055109bc578ad490ac8fd30312c 286 PIRSF PIRSF003085 1 286 2.5E-108 T 06-07-2017 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 CAK77_RS16935 184870323a79bc956670ffa1b49d8588 284 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 3.2E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS16935 184870323a79bc956670ffa1b49d8588 284 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 3.2E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS16935 184870323a79bc956670ffa1b49d8588 284 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 3.2E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS16935 184870323a79bc956670ffa1b49d8588 284 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 3.2E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS16935 184870323a79bc956670ffa1b49d8588 284 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 198 218 3.2E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS16935 184870323a79bc956670ffa1b49d8588 284 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 3.2E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS16935 184870323a79bc956670ffa1b49d8588 284 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 194 0.004 T 06-07-2017 CAK77_RS16935 184870323a79bc956670ffa1b49d8588 284 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK77_RS16935 184870323a79bc956670ffa1b49d8588 284 Gene3D G3DSA:3.40.50.720 5 225 4.7E-73 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS16935 184870323a79bc956670ffa1b49d8588 284 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 1.2E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS16935 184870323a79bc956670ffa1b49d8588 284 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 1.2E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS16935 184870323a79bc956670ffa1b49d8588 284 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 1.2E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS16935 184870323a79bc956670ffa1b49d8588 284 Pfam PF00106 short chain dehydrogenase 7 192 2.1E-55 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS16935 184870323a79bc956670ffa1b49d8588 284 SUPERFAMILY SSF51735 3 250 5.72E-70 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS02695 0f0d41efe884b1d6eef11a3b7486a9cb 173 Pfam PF09349 OHCU decarboxylase 13 161 1.4E-33 T 06-07-2017 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394 CAK77_RS02695 0f0d41efe884b1d6eef11a3b7486a9cb 173 Gene3D G3DSA:1.10.3330.10 14 165 1.7E-35 T 06-07-2017 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394 CAK77_RS02695 0f0d41efe884b1d6eef11a3b7486a9cb 173 SUPERFAMILY SSF158694 10 164 3.66E-37 T 06-07-2017 CAK77_RS01900 e79e20fe28f04a96618eda122cf33ebe 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 3.3E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS01900 e79e20fe28f04a96618eda122cf33ebe 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 3.3E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS01900 e79e20fe28f04a96618eda122cf33ebe 203 Gene3D G3DSA:1.10.357.10 1 187 7.7E-27 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS01900 e79e20fe28f04a96618eda122cf33ebe 203 SUPERFAMILY SSF46689 5 83 5.49E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS01900 e79e20fe28f04a96618eda122cf33ebe 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 64 4.8E-14 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS12950 0d88ccb87366bad6b214811ee3d378b1 557 SMART SM00382 369 553 7.5E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS12950 0d88ccb87366bad6b214811ee3d378b1 557 TIGRFAM TIGR02857 CydD: thiol reductant ABC exporter, CydD subunit 20 548 1.1E-151 T 06-07-2017 IPR014216 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD GO:0005524|GO:0016020|GO:0042883 CAK77_RS12950 0d88ccb87366bad6b214811ee3d378b1 557 Pfam PF00664 ABC transporter transmembrane region 24 282 8.8E-16 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAK77_RS12950 0d88ccb87366bad6b214811ee3d378b1 557 SUPERFAMILY SSF90123 10 329 6.28E-45 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAK77_RS12950 0d88ccb87366bad6b214811ee3d378b1 557 Gene3D G3DSA:3.40.50.300 363 549 7.8E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS12950 0d88ccb87366bad6b214811ee3d378b1 557 Gene3D G3DSA:1.20.1560.10 11 329 8.2E-39 T 06-07-2017 CAK77_RS12950 0d88ccb87366bad6b214811ee3d378b1 557 Pfam PF00005 ABC transporter 363 506 5.8E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK77_RS12950 0d88ccb87366bad6b214811ee3d378b1 557 ProSitePatterns PS00211 ABC transporters family signature. 478 492 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK77_RS12950 0d88ccb87366bad6b214811ee3d378b1 557 SUPERFAMILY SSF52540 336 549 3.2E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS07655 e5340c05bc3ce2f06e44d94646fef7bb 967 SUPERFAMILY SSF82866 142 345 1.96E-30 T 06-07-2017 CAK77_RS07655 e5340c05bc3ce2f06e44d94646fef7bb 967 Pfam PF03176 MMPL family 45 375 2.8E-94 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 CAK77_RS07655 e5340c05bc3ce2f06e44d94646fef7bb 967 Pfam PF03176 MMPL family 604 940 1.5E-66 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 CAK77_RS07655 e5340c05bc3ce2f06e44d94646fef7bb 967 Gene3D G3DSA:1.20.1640.10 141 352 3.6E-31 T 06-07-2017 CAK77_RS07655 e5340c05bc3ce2f06e44d94646fef7bb 967 Gene3D G3DSA:1.20.1640.10 729 929 1.2E-21 T 06-07-2017 CAK77_RS07655 e5340c05bc3ce2f06e44d94646fef7bb 967 SUPERFAMILY SSF82866 722 927 1.22E-25 T 06-07-2017 CAK77_RS07655 e5340c05bc3ce2f06e44d94646fef7bb 967 SUPERFAMILY SSF58104 465 659 6.28E-6 T 06-07-2017 CAK77_RS09575 67c7926128009751d15bdf2078d29fe9 361 SUPERFAMILY SSF52418 85 352 2.35E-78 T 06-07-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CAK77_RS09575 67c7926128009751d15bdf2078d29fe9 361 Gene3D G3DSA:1.20.970.10 5 69 2.0E-19 T 06-07-2017 CAK77_RS09575 67c7926128009751d15bdf2078d29fe9 361 Pfam PF02885 Glycosyl transferase family, helical bundle domain 12 69 3.8E-14 T 06-07-2017 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CAK77_RS09575 67c7926128009751d15bdf2078d29fe9 361 Pfam PF00591 Glycosyl transferase family, a/b domain 84 339 1.8E-87 T 06-07-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CAK77_RS09575 67c7926128009751d15bdf2078d29fe9 361 SUPERFAMILY SSF47648 6 72 9.42E-16 T 06-07-2017 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CAK77_RS09575 67c7926128009751d15bdf2078d29fe9 361 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 11 348 1.3E-111 T 06-07-2017 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 CAK77_RS09575 67c7926128009751d15bdf2078d29fe9 361 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 8 349 33.439 T 06-07-2017 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 CAK77_RS09575 67c7926128009751d15bdf2078d29fe9 361 Gene3D G3DSA:3.40.1030.10 83 351 3.3E-100 T 06-07-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CAK77_RS23050 e76e3e65d10f1f69418b8a20bd1f123e 286 Pfam PF09339 IclR helix-turn-helix domain 9 58 7.4E-10 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAK77_RS23050 e76e3e65d10f1f69418b8a20bd1f123e 286 SMART SM00346 5 89 0.005 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAK77_RS23050 e76e3e65d10f1f69418b8a20bd1f123e 286 SUPERFAMILY SSF55781 62 178 6.54E-6 T 06-07-2017 IPR029016 GAF domain-like CAK77_RS23050 e76e3e65d10f1f69418b8a20bd1f123e 286 Gene3D G3DSA:3.30.450.40 237 284 4.8E-8 T 06-07-2017 IPR029016 GAF domain-like CAK77_RS23050 e76e3e65d10f1f69418b8a20bd1f123e 286 Gene3D G3DSA:3.30.450.40 75 187 4.8E-8 T 06-07-2017 IPR029016 GAF domain-like CAK77_RS23050 e76e3e65d10f1f69418b8a20bd1f123e 286 Gene3D G3DSA:1.10.10.10 7 68 9.1E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS23050 e76e3e65d10f1f69418b8a20bd1f123e 286 SUPERFAMILY SSF46785 9 68 1.55E-10 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS00290 e9f47db0fcfc8de08ce72edd8471ae37 178 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 13 176 1.6E-47 T 06-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CAK77_RS00290 e9f47db0fcfc8de08ce72edd8471ae37 178 SUPERFAMILY SSF50891 11 177 5.26E-62 T 06-07-2017 IPR029000 Cyclophilin-like domain CAK77_RS00290 e9f47db0fcfc8de08ce72edd8471ae37 178 Gene3D G3DSA:2.40.100.10 6 177 4.4E-64 T 06-07-2017 IPR029000 Cyclophilin-like domain CAK77_RS00290 e9f47db0fcfc8de08ce72edd8471ae37 178 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 62 79 - T 06-07-2017 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 CAK77_RS00290 e9f47db0fcfc8de08ce72edd8471ae37 178 PIRSF PIRSF001467 3 178 4.5E-59 T 06-07-2017 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755|GO:0006457 CAK77_RS00290 e9f47db0fcfc8de08ce72edd8471ae37 178 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 135 150 4.6E-26 T 06-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CAK77_RS00290 e9f47db0fcfc8de08ce72edd8471ae37 178 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 107 122 4.6E-26 T 06-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CAK77_RS00290 e9f47db0fcfc8de08ce72edd8471ae37 178 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 67 79 4.6E-26 T 06-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CAK77_RS00290 e9f47db0fcfc8de08ce72edd8471ae37 178 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 26 41 4.6E-26 T 06-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CAK77_RS00290 e9f47db0fcfc8de08ce72edd8471ae37 178 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 122 134 4.6E-26 T 06-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CAK77_RS15285 bb87050aa8e4a4992342927fb67e6299 312 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 199 216 9.8E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS15285 bb87050aa8e4a4992342927fb67e6299 312 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 17 34 9.8E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS15285 bb87050aa8e4a4992342927fb67e6299 312 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 93 104 9.8E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS15285 bb87050aa8e4a4992342927fb67e6299 312 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 138 154 9.8E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS15285 bb87050aa8e4a4992342927fb67e6299 312 Gene3D G3DSA:3.40.50.720 13 239 1.7E-46 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS15285 bb87050aa8e4a4992342927fb67e6299 312 SUPERFAMILY SSF51735 13 247 1.21E-45 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS15285 bb87050aa8e4a4992342927fb67e6299 312 Pfam PF00106 short chain dehydrogenase 17 217 9.5E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS21440 2bc530e5466dc528b35355a2e3c61522 305 SUPERFAMILY SSF55961 9 146 1.83E-21 T 06-07-2017 CAK77_RS21440 2bc530e5466dc528b35355a2e3c61522 305 SUPERFAMILY SSF55961 153 301 7.41E-19 T 06-07-2017 CAK77_RS21440 2bc530e5466dc528b35355a2e3c61522 305 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 19 144 4.1E-16 T 06-07-2017 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CAK77_RS21440 2bc530e5466dc528b35355a2e3c61522 305 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 171 278 9.3E-8 T 06-07-2017 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CAK77_RS21440 2bc530e5466dc528b35355a2e3c61522 305 Gene3D G3DSA:3.30.530.20 6 147 1.8E-21 T 06-07-2017 IPR023393 START-like domain CAK77_RS21440 2bc530e5466dc528b35355a2e3c61522 305 Gene3D G3DSA:3.30.530.20 159 301 9.6E-17 T 06-07-2017 IPR023393 START-like domain CAK77_RS06160 387cd7f3ce6f93d6d8ce27f4c531e64e 261 SUPERFAMILY SSF161098 64 249 1.26E-31 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS06160 387cd7f3ce6f93d6d8ce27f4c531e64e 261 Gene3D G3DSA:1.10.3720.10 20 248 8.1E-25 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS06160 387cd7f3ce6f93d6d8ce27f4c531e64e 261 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 86 253 3.2E-20 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS08995 a1dc27118a883048bfae38433fde290e 272 SUPERFAMILY SSF56601 7 267 7.89E-48 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK77_RS08995 a1dc27118a883048bfae38433fde290e 272 Pfam PF00144 Beta-lactamase 34 253 1.4E-31 T 06-07-2017 IPR001466 Beta-lactamase-related CAK77_RS08995 a1dc27118a883048bfae38433fde290e 272 Gene3D G3DSA:3.40.710.10 35 268 3.4E-37 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK77_RS08550 01ad5775d152f0478cb4ab0ad9dc0375 152 Pfam PF01475 Ferric uptake regulator family 23 138 4.6E-32 T 06-07-2017 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 CAK77_RS08550 01ad5775d152f0478cb4ab0ad9dc0375 152 SUPERFAMILY SSF46785 23 143 6.12E-32 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS08550 01ad5775d152f0478cb4ab0ad9dc0375 152 Gene3D G3DSA:1.10.10.10 23 91 1.5E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS06970 c528f638c7597261d75d5f7249d2d3cc 439 SUPERFAMILY SSF53474 304 397 1.26E-12 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS06970 c528f638c7597261d75d5f7249d2d3cc 439 SUPERFAMILY SSF53474 115 237 1.26E-12 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS06970 c528f638c7597261d75d5f7249d2d3cc 439 Gene3D G3DSA:3.40.50.1820 116 218 2.8E-9 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS06970 c528f638c7597261d75d5f7249d2d3cc 439 Gene3D G3DSA:3.40.50.1820 256 381 2.8E-9 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS06970 c528f638c7597261d75d5f7249d2d3cc 439 Pfam PF03583 Secretory lipase 131 401 2.4E-59 T 06-07-2017 IPR005152 Lipase, secreted GO:0004806|GO:0016042 KEGG: 00561+3.1.1.3|MetaCyc: PWY-6857 CAK77_RS16700 86925ba05346e53af7ddd7ad945e2ea4 289 SUPERFAMILY SSF69593 44 216 7.45E-23 T 06-07-2017 CAK77_RS16700 86925ba05346e53af7ddd7ad945e2ea4 289 Pfam PF01553 Acyltransferase 84 201 1.1E-19 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CAK77_RS16700 86925ba05346e53af7ddd7ad945e2ea4 289 SMART SM00563 93 205 2.4E-26 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CAK77_RS10475 fa153e2f9e5d24388d21dad19ff930a1 221 Pfam PF00440 Bacterial regulatory proteins, tetR family 42 88 1.0E-14 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS10475 fa153e2f9e5d24388d21dad19ff930a1 221 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 63 86 4.8E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS10475 fa153e2f9e5d24388d21dad19ff930a1 221 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 55 4.8E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS10475 fa153e2f9e5d24388d21dad19ff930a1 221 Gene3D G3DSA:1.10.357.10 40 218 3.5E-23 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS10475 fa153e2f9e5d24388d21dad19ff930a1 221 SUPERFAMILY SSF46689 38 113 1.23E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS11880 2bb6048c7410eefc1988fa8e3af38851 326 Pfam PF05726 Pirin C-terminal cupin domain 205 313 1.7E-31 T 06-07-2017 IPR008778 Pirin, C-terminal domain CAK77_RS11880 2bb6048c7410eefc1988fa8e3af38851 326 PIRSF PIRSF006232 25 319 3.6E-82 T 06-07-2017 IPR012093 Pirin CAK77_RS11880 2bb6048c7410eefc1988fa8e3af38851 326 Pfam PF02678 Pirin 55 149 3.0E-29 T 06-07-2017 IPR003829 Pirin, N-terminal domain CAK77_RS11880 2bb6048c7410eefc1988fa8e3af38851 326 Gene3D G3DSA:2.60.120.10 26 285 3.6E-74 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK77_RS11880 2bb6048c7410eefc1988fa8e3af38851 326 SUPERFAMILY SSF51182 27 317 1.32E-78 T 06-07-2017 IPR011051 RmlC-like cupin domain CAK77_RS14760 360007444934eff9787bc9869d578181 239 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 71 1.4E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS14760 360007444934eff9787bc9869d578181 239 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 47 70 2.0E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS14760 360007444934eff9787bc9869d578181 239 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 40 2.0E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS14760 360007444934eff9787bc9869d578181 239 SUPERFAMILY SSF48498 94 186 1.56E-6 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS14760 360007444934eff9787bc9869d578181 239 SUPERFAMILY SSF46689 14 88 2.89E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS14760 360007444934eff9787bc9869d578181 239 Gene3D G3DSA:1.10.357.10 9 209 6.2E-32 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS01790 d3182e623db44fe848e8bc3e5b9e7d8f 377 Pfam PF03060 Nitronate monooxygenase 21 300 1.4E-41 T 06-07-2017 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 CAK77_RS01790 d3182e623db44fe848e8bc3e5b9e7d8f 377 Gene3D G3DSA:3.20.20.70 1 103 5.7E-58 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK77_RS01790 d3182e623db44fe848e8bc3e5b9e7d8f 377 Gene3D G3DSA:3.20.20.70 154 352 5.7E-58 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK77_RS01790 d3182e623db44fe848e8bc3e5b9e7d8f 377 SUPERFAMILY SSF51412 117 349 5.95E-46 T 06-07-2017 CAK77_RS01790 d3182e623db44fe848e8bc3e5b9e7d8f 377 SUPERFAMILY SSF51412 23 58 5.95E-46 T 06-07-2017 CAK77_RS04915 ff3e317383cf56601f504d1d536337cd 173 Gene3D G3DSA:1.10.10.60 4 38 3.3E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS04915 ff3e317383cf56601f504d1d536337cd 173 Gene3D G3DSA:1.10.357.10 39 166 8.9E-28 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS04915 ff3e317383cf56601f504d1d536337cd 173 Pfam PF00440 Bacterial regulatory proteins, tetR family 4 42 2.8E-12 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS04915 ff3e317383cf56601f504d1d536337cd 173 SUPERFAMILY SSF48498 57 166 4.38E-18 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS04915 ff3e317383cf56601f504d1d536337cd 173 SUPERFAMILY SSF46689 3 47 4.84E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS04915 ff3e317383cf56601f504d1d536337cd 173 Pfam PF16859 Bacterial transcriptional repressor C-terminal 54 162 4.1E-24 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS04915 ff3e317383cf56601f504d1d536337cd 173 ProSitePatterns PS01081 TetR-type HTH domain signature. 8 39 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CAK77_RS15585 5caee90e5a91934157a050e054f1fcb3 137 SUPERFAMILY SSF46785 2 132 2.32E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS15585 5caee90e5a91934157a050e054f1fcb3 137 Gene3D G3DSA:1.10.10.10 2 135 1.3E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS15585 5caee90e5a91934157a050e054f1fcb3 137 Pfam PF02082 Transcriptional regulator 2 70 5.2E-13 T 06-07-2017 IPR000944 Transcription regulator Rrf2-type CAK77_RS11200 f0828edb038474f46ddf500247ec8d76 133 Pfam PF05423 Mycobacterium membrane protein 1 133 6.6E-46 T 06-07-2017 IPR008693 Transport accessory protein MmpS CAK77_RS01705 43f593112ba0dafd7bf301fdad975724 607 SUPERFAMILY SSF51569 58 366 6.41E-90 T 06-07-2017 CAK77_RS01705 43f593112ba0dafd7bf301fdad975724 607 SMART SM00917 468 605 4.6E-34 T 06-07-2017 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CAK77_RS01705 43f593112ba0dafd7bf301fdad975724 607 Gene3D G3DSA:3.20.20.70 49 440 3.2E-141 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK77_RS01705 43f593112ba0dafd7bf301fdad975724 607 Hamap MF_00572 2-isopropylmalate synthase [leuA]. 40 606 54.548 T 06-07-2017 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CAK77_RS01705 43f593112ba0dafd7bf301fdad975724 607 Pfam PF00682 HMGL-like 69 349 7.1E-73 T 06-07-2017 IPR000891 Pyruvate carboxyltransferase GO:0003824 CAK77_RS01705 43f593112ba0dafd7bf301fdad975724 607 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 76 92 - T 06-07-2017 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CAK77_RS01705 43f593112ba0dafd7bf301fdad975724 607 SUPERFAMILY SSF110921 490 604 7.45E-36 T 06-07-2017 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CAK77_RS01705 43f593112ba0dafd7bf301fdad975724 607 TIGRFAM TIGR00970 leuA_yeast: 2-isopropylmalate synthase 39 606 9.7E-288 T 06-07-2017 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CAK77_RS01705 43f593112ba0dafd7bf301fdad975724 607 Pfam PF08502 LeuA allosteric (dimerisation) domain 468 604 2.9E-31 T 06-07-2017 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CAK77_RS01705 43f593112ba0dafd7bf301fdad975724 607 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 279 292 - T 06-07-2017 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CAK77_RS01705 43f593112ba0dafd7bf301fdad975724 607 SUPERFAMILY SSF89000 434 483 8.24E-15 T 06-07-2017 CAK77_RS12845 8264e8ff39c6a9bfc289a4daa0764e1c 361 SUPERFAMILY SSF55347 124 284 1.52E-20 T 06-07-2017 CAK77_RS12845 8264e8ff39c6a9bfc289a4daa0764e1c 361 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 2 109 1.3E-25 T 06-07-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 CAK77_RS12845 8264e8ff39c6a9bfc289a4daa0764e1c 361 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 133 193 5.5E-8 T 06-07-2017 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 CAK77_RS12845 8264e8ff39c6a9bfc289a4daa0764e1c 361 Gene3D G3DSA:3.30.360.10 130 340 3.0E-27 T 06-07-2017 CAK77_RS12845 8264e8ff39c6a9bfc289a4daa0764e1c 361 SUPERFAMILY SSF51735 2 146 3.31E-41 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS12845 8264e8ff39c6a9bfc289a4daa0764e1c 361 Gene3D G3DSA:3.40.50.720 1 129 9.5E-37 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS13355 9a11ba75c7bf112621bc353a88abf612 381 Gene3D G3DSA:1.10.8.300 230 346 5.3E-36 T 06-07-2017 CAK77_RS13355 9a11ba75c7bf112621bc353a88abf612 381 Gene3D G3DSA:3.40.50.300 52 216 6.6E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS13355 9a11ba75c7bf112621bc353a88abf612 381 PIRSF PIRSF002849 17 351 9.2E-134 T 06-07-2017 IPR016366 ATPase chaperone, AAA-type, MoxR, predicted CAK77_RS13355 9a11ba75c7bf112621bc353a88abf612 381 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 70 200 7.9E-60 T 06-07-2017 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 CAK77_RS13355 9a11ba75c7bf112621bc353a88abf612 381 SUPERFAMILY SSF52540 44 321 4.72E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS03365 797f7fbf11c88194a09874f8ba28e829 391 SUPERFAMILY SSF51905 263 366 5.1E-54 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS03365 797f7fbf11c88194a09874f8ba28e829 391 SUPERFAMILY SSF51905 4 164 5.1E-54 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS03365 797f7fbf11c88194a09874f8ba28e829 391 Pfam PF01494 FAD binding domain 4 159 2.3E-12 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 CAK77_RS03365 797f7fbf11c88194a09874f8ba28e829 391 Pfam PF01494 FAD binding domain 271 311 5.5E-6 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 CAK77_RS03365 797f7fbf11c88194a09874f8ba28e829 391 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 3.1E-15 T 06-07-2017 CAK77_RS03365 797f7fbf11c88194a09874f8ba28e829 391 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 276 291 3.1E-15 T 06-07-2017 CAK77_RS03365 797f7fbf11c88194a09874f8ba28e829 391 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 291 307 3.1E-15 T 06-07-2017 CAK77_RS03365 797f7fbf11c88194a09874f8ba28e829 391 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 143 158 3.1E-15 T 06-07-2017 CAK77_RS03365 797f7fbf11c88194a09874f8ba28e829 391 Gene3D G3DSA:3.50.50.60 264 337 1.0E-29 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS03365 797f7fbf11c88194a09874f8ba28e829 391 Gene3D G3DSA:3.50.50.60 3 170 1.0E-29 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS23720 1368c2939681419fe9eea5c024a0fa40 648 SUPERFAMILY SSF58104 169 405 7.06E-7 T 06-07-2017 CAK77_RS23720 1368c2939681419fe9eea5c024a0fa40 648 Pfam PF12698 ABC-2 family transporter protein 416 630 3.2E-13 T 06-07-2017 CAK77_RS23720 1368c2939681419fe9eea5c024a0fa40 648 TIGRFAM TIGR03061 pip_yhgE_Nterm: YhgE/Pip N-terminal domain 9 172 2.2E-57 T 06-07-2017 IPR017500 Phage infection protein, YhgE, N-terminal CAK77_RS23720 1368c2939681419fe9eea5c024a0fa40 648 TIGRFAM TIGR03062 pip_yhgE_Cterm: YhgE/Pip C-terminal domain 428 635 1.6E-71 T 06-07-2017 IPR017501 Phage infection protein, YhgE, C-terminal CAK77_RS23720 1368c2939681419fe9eea5c024a0fa40 648 Pfam PF12051 Protein of unknown function (DUF3533) 24 187 1.2E-10 T 06-07-2017 IPR022703 Domain of unknown function DUF3533 CAK77_RS23720 1368c2939681419fe9eea5c024a0fa40 648 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 354 380 7.3E-5 T 06-07-2017 IPR023908 xxxLxxG heptad repeat CAK77_RS23720 1368c2939681419fe9eea5c024a0fa40 648 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 180 202 2.3E-4 T 06-07-2017 IPR023908 xxxLxxG heptad repeat CAK77_RS23720 1368c2939681419fe9eea5c024a0fa40 648 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 190 212 2.8E-5 T 06-07-2017 IPR023908 xxxLxxG heptad repeat CAK77_RS23720 1368c2939681419fe9eea5c024a0fa40 648 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 216 236 3.3E-4 T 06-07-2017 IPR023908 xxxLxxG heptad repeat CAK77_RS23720 1368c2939681419fe9eea5c024a0fa40 648 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 383 407 4.4E-6 T 06-07-2017 IPR023908 xxxLxxG heptad repeat CAK77_RS06100 324e19c50ba9c791f4f6aec6bfe12e9a 275 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 2.8E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06100 324e19c50ba9c791f4f6aec6bfe12e9a 275 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 2.8E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06100 324e19c50ba9c791f4f6aec6bfe12e9a 275 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 86 97 2.8E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06100 324e19c50ba9c791f4f6aec6bfe12e9a 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 6.5E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06100 324e19c50ba9c791f4f6aec6bfe12e9a 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 6.5E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06100 324e19c50ba9c791f4f6aec6bfe12e9a 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 6.5E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06100 324e19c50ba9c791f4f6aec6bfe12e9a 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 6.5E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06100 324e19c50ba9c791f4f6aec6bfe12e9a 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 6.5E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06100 324e19c50ba9c791f4f6aec6bfe12e9a 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 239 6.5E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06100 324e19c50ba9c791f4f6aec6bfe12e9a 275 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 146 174 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK77_RS06100 324e19c50ba9c791f4f6aec6bfe12e9a 275 Pfam PF00106 short chain dehydrogenase 14 203 2.9E-45 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06100 324e19c50ba9c791f4f6aec6bfe12e9a 275 SUPERFAMILY SSF51735 14 241 2.32E-57 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS06100 324e19c50ba9c791f4f6aec6bfe12e9a 275 Gene3D G3DSA:3.40.50.720 14 241 2.2E-59 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS18770 f38eaa6412b1c54ea1a2413d5ab56c5c 228 SMART SM01110 44 227 4.8E-60 T 06-07-2017 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 CAK77_RS18770 f38eaa6412b1c54ea1a2413d5ab56c5c 228 Pfam PF01083 Cutinase 45 226 1.8E-42 T 06-07-2017 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 CAK77_RS18770 f38eaa6412b1c54ea1a2413d5ab56c5c 228 SUPERFAMILY SSF53474 46 227 2.35E-33 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS18770 f38eaa6412b1c54ea1a2413d5ab56c5c 228 ProSitePatterns PS00155 Cutinase, serine active site. 113 125 - T 06-07-2017 IPR011150 Cutinase, monofunctional GO:0005576|GO:0050525 CAK77_RS18770 f38eaa6412b1c54ea1a2413d5ab56c5c 228 Gene3D G3DSA:3.40.50.1820 45 227 3.3E-45 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS19025 aabe7cf0c4826866289cb3a66fcb1d61 78 ProSitePatterns PS00579 Ribosomal protein L29 signature. 43 57 - T 06-07-2017 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK77_RS19025 aabe7cf0c4826866289cb3a66fcb1d61 78 Gene3D G3DSA:1.10.287.310 7 68 3.5E-27 T 06-07-2017 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK77_RS19025 aabe7cf0c4826866289cb3a66fcb1d61 78 Pfam PF00831 Ribosomal L29 protein 9 64 2.5E-22 T 06-07-2017 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK77_RS19025 aabe7cf0c4826866289cb3a66fcb1d61 78 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 5 64 16.001 T 06-07-2017 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK77_RS19025 aabe7cf0c4826866289cb3a66fcb1d61 78 TIGRFAM TIGR00012 L29: ribosomal protein uL29 9 64 1.1E-19 T 06-07-2017 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK77_RS19025 aabe7cf0c4826866289cb3a66fcb1d61 78 SUPERFAMILY SSF46561 7 67 8.63E-21 T 06-07-2017 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK77_RS16955 5cc64972389c0ad8a0764ab34d0b9079 237 SUPERFAMILY SSF53850 18 194 6.79E-27 T 06-07-2017 CAK77_RS16955 5cc64972389c0ad8a0764ab34d0b9079 237 Gene3D G3DSA:3.40.190.10 23 84 1.6E-13 T 06-07-2017 CAK77_RS16955 5cc64972389c0ad8a0764ab34d0b9079 237 Pfam PF03466 LysR substrate binding domain 19 189 3.7E-28 T 06-07-2017 IPR005119 LysR, substrate-binding CAK77_RS16955 5cc64972389c0ad8a0764ab34d0b9079 237 Gene3D G3DSA:3.40.190.10 85 163 9.4E-11 T 06-07-2017 CAK77_RS23790 334a6009df53e63bad82fb30b40c4a1c 265 Pfam PF03734 L,D-transpeptidase catalytic domain 161 263 1.2E-12 T 06-07-2017 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 CAK77_RS23790 334a6009df53e63bad82fb30b40c4a1c 265 SUPERFAMILY SSF141523 161 263 3.4E-25 T 06-07-2017 CAK77_RS23790 334a6009df53e63bad82fb30b40c4a1c 265 Gene3D G3DSA:2.40.440.10 161 264 2.4E-16 T 06-07-2017 CAK77_RS17720 f0e26050101d56b51d881c631f4d675e 325 Pfam PF00781 Diacylglycerol kinase catalytic domain 3 118 3.0E-27 T 06-07-2017 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CAK77_RS17720 f0e26050101d56b51d881c631f4d675e 325 SUPERFAMILY SSF111331 2 318 9.16E-51 T 06-07-2017 IPR016064 NAD kinase/diacylglycerol kinase-like domain CAK77_RS17720 f0e26050101d56b51d881c631f4d675e 325 SMART SM00046 2 131 1.5E-25 T 06-07-2017 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CAK77_RS10305 0113aa9b6e147368b812fade3fb47a64 441 SUPERFAMILY SSF53901 6 371 1.23E-76 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS10305 0113aa9b6e147368b812fade3fb47a64 441 SUPERFAMILY SSF53901 406 427 1.23E-76 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS10305 0113aa9b6e147368b812fade3fb47a64 441 Gene3D G3DSA:3.40.47.10 9 268 7.3E-74 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS10305 0113aa9b6e147368b812fade3fb47a64 441 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 264 376 7.3E-29 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAK77_RS10305 0113aa9b6e147368b812fade3fb47a64 441 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 169 185 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site CAK77_RS10305 0113aa9b6e147368b812fade3fb47a64 441 Gene3D G3DSA:3.40.47.10 272 428 2.2E-44 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS10305 0113aa9b6e147368b812fade3fb47a64 441 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 7 256 1.2E-70 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAK77_RS10305 0113aa9b6e147368b812fade3fb47a64 441 SMART SM00825 Beta-ketoacyl synthase 9 431 4.2E-110 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAK77_RS21305 8304ebd21020f845dcb53756dd328cab 452 SUPERFAMILY SSF51735 152 405 1.33E-38 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS21305 8304ebd21020f845dcb53756dd328cab 452 Pfam PF08338 Domain of unknown function (DUF1731) 397 445 1.3E-9 T 06-07-2017 IPR013549 Domain of unknown function DUF1731 CAK77_RS21305 8304ebd21020f845dcb53756dd328cab 452 Pfam PF01370 NAD dependent epimerase/dehydratase family 155 359 1.9E-16 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 CAK77_RS21305 8304ebd21020f845dcb53756dd328cab 452 TIGRFAM TIGR01777 yfcH: TIGR01777 family protein 154 442 5.8E-84 T 06-07-2017 IPR010099 Epimerase family protein SDR39U1 CAK77_RS21305 8304ebd21020f845dcb53756dd328cab 452 Gene3D G3DSA:3.40.50.720 153 394 2.1E-24 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS21305 8304ebd21020f845dcb53756dd328cab 452 SUPERFAMILY SSF55961 3 136 3.67E-12 T 06-07-2017 CAK77_RS15470 fbd7ab36df39d9571d8e1c0aaad5e7c7 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 10 88 3.0E-24 T 06-07-2017 CAK77_RS15470 fbd7ab36df39d9571d8e1c0aaad5e7c7 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 22.49 T 06-07-2017 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS15470 fbd7ab36df39d9571d8e1c0aaad5e7c7 89 SUPERFAMILY SSF47060 3 89 3.53E-35 T 06-07-2017 IPR009068 S15/NS1, RNA-binding CAK77_RS15470 fbd7ab36df39d9571d8e1c0aaad5e7c7 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 4 89 7.9E-40 T 06-07-2017 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS15470 fbd7ab36df39d9571d8e1c0aaad5e7c7 89 Pfam PF00312 Ribosomal protein S15 8 88 1.3E-37 T 06-07-2017 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS15470 fbd7ab36df39d9571d8e1c0aaad5e7c7 89 SMART SM01387 8 88 2.1E-51 T 06-07-2017 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS15470 fbd7ab36df39d9571d8e1c0aaad5e7c7 89 Gene3D G3DSA:1.10.287.10 3 89 1.6E-38 T 06-07-2017 IPR009068 S15/NS1, RNA-binding CAK77_RS15470 fbd7ab36df39d9571d8e1c0aaad5e7c7 89 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 06-07-2017 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS04465 2b5d73e849ccc219c9b379f2d739b0bd 436 Gene3D G3DSA:1.20.1250.20 41 199 2.8E-20 T 06-07-2017 CAK77_RS04465 2b5d73e849ccc219c9b379f2d739b0bd 436 SUPERFAMILY SSF103473 14 400 5.89E-52 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK77_RS04465 2b5d73e849ccc219c9b379f2d739b0bd 436 Gene3D G3DSA:1.20.1250.20 220 402 1.7E-17 T 06-07-2017 CAK77_RS04465 2b5d73e849ccc219c9b379f2d739b0bd 436 Pfam PF05977 Transmembrane secretion effector 11 394 3.0E-54 T 06-07-2017 IPR010290 Transmembrane secretion effector CAK77_RS01230 51d596fa2eb1646df6a3b893e46ab6bd 232 SUPERFAMILY SSF46785 8 190 1.64E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS01230 51d596fa2eb1646df6a3b893e46ab6bd 232 Pfam PF08461 Ribonuclease R winged-helix domain 14 61 2.3E-7 T 06-07-2017 IPR013668 Ribonuclease R winged-helix domain CAK77_RS01230 51d596fa2eb1646df6a3b893e46ab6bd 232 Gene3D G3DSA:1.10.10.10 10 62 6.1E-9 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS00770 57d21475035527c1fbc2b3b685be0a20 108 Pfam PF00581 Rhodanese-like domain 24 101 1.4E-15 T 06-07-2017 IPR001763 Rhodanese-like domain CAK77_RS00770 57d21475035527c1fbc2b3b685be0a20 108 SUPERFAMILY SSF52821 8 108 1.57E-33 T 06-07-2017 IPR001763 Rhodanese-like domain CAK77_RS00770 57d21475035527c1fbc2b3b685be0a20 108 SMART SM00450 12 105 1.2E-20 T 06-07-2017 IPR001763 Rhodanese-like domain CAK77_RS00770 57d21475035527c1fbc2b3b685be0a20 108 Gene3D G3DSA:3.40.250.10 8 107 1.7E-31 T 06-07-2017 IPR001763 Rhodanese-like domain CAK77_RS07405 117fdef65da830effd924c12ef797103 184 SUPERFAMILY SSF52499 3 183 2.35E-43 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAK77_RS07405 117fdef65da830effd924c12ef797103 184 Gene3D G3DSA:3.40.50.850 3 183 1.0E-52 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAK77_RS07405 117fdef65da830effd924c12ef797103 184 Pfam PF00857 Isochorismatase family 4 183 1.5E-28 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAK77_RS07000 c324d8798529f8c61a820c9e2a3da073 442 Gene3D G3DSA:3.30.43.10 3 92 2.9E-18 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CAK77_RS07000 c324d8798529f8c61a820c9e2a3da073 442 Pfam PF02913 FAD linked oxidases, C-terminal domain 215 435 3.4E-42 T 06-07-2017 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 CAK77_RS07000 c324d8798529f8c61a820c9e2a3da073 442 Pfam PF01565 FAD binding domain 40 175 2.4E-33 T 06-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CAK77_RS07000 c324d8798529f8c61a820c9e2a3da073 442 Gene3D G3DSA:1.10.45.10 398 434 4.2E-7 T 06-07-2017 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 CAK77_RS07000 c324d8798529f8c61a820c9e2a3da073 442 SUPERFAMILY SSF55103 219 438 2.13E-40 T 06-07-2017 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CAK77_RS07000 c324d8798529f8c61a820c9e2a3da073 442 Gene3D G3DSA:3.30.465.10 98 215 5.7E-35 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAK77_RS07000 c324d8798529f8c61a820c9e2a3da073 442 SUPERFAMILY SSF56176 2 215 3.0E-61 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAK77_RS17195 75f727098ab66068affb8e35436f4f6f 543 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 208 313 2.5E-10 T 06-07-2017 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK77_RS17195 75f727098ab66068affb8e35436f4f6f 543 Gene3D G3DSA:3.40.120.10 308 443 4.9E-34 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK77_RS17195 75f727098ab66068affb8e35436f4f6f 543 Gene3D G3DSA:3.40.120.10 28 222 3.1E-57 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK77_RS17195 75f727098ab66068affb8e35436f4f6f 543 SUPERFAMILY SSF53738 304 446 5.49E-32 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK77_RS17195 75f727098ab66068affb8e35436f4f6f 543 Gene3D G3DSA:3.30.310.50 465 542 1.3E-28 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK77_RS17195 75f727098ab66068affb8e35436f4f6f 543 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 319 439 5.0E-29 T 06-07-2017 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK77_RS17195 75f727098ab66068affb8e35436f4f6f 543 SUPERFAMILY SSF53738 24 233 7.06E-47 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK77_RS17195 75f727098ab66068affb8e35436f4f6f 543 TIGRFAM TIGR01132 pgm: phosphoglucomutase, alpha-D-glucose phosphate-specific 3 543 4.1E-289 T 06-07-2017 IPR005852 Phosphoglucomutase, alpha-D-glucose specific GO:0004614|GO:0005975 KEGG: 00010+5.4.2.2|KEGG: 00030+5.4.2.2|KEGG: 00052+5.4.2.2|KEGG: 00230+5.4.2.2|KEGG: 00500+5.4.2.2|KEGG: 00520+5.4.2.2|KEGG: 00521+5.4.2.2|MetaCyc: PWY-2723|MetaCyc: PWY-3801|MetaCyc: PWY-5384|MetaCyc: PWY-5661|MetaCyc: PWY-5940|MetaCyc: PWY-5941|MetaCyc: PWY-622|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|MetaCyc: PWY-7343 CAK77_RS17195 75f727098ab66068affb8e35436f4f6f 543 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 140 149 - T 06-07-2017 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK77_RS17195 75f727098ab66068affb8e35436f4f6f 543 SUPERFAMILY SSF55957 434 543 3.92E-20 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK77_RS17195 75f727098ab66068affb8e35436f4f6f 543 SUPERFAMILY SSF53738 207 314 4.36E-5 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK77_RS17195 75f727098ab66068affb8e35436f4f6f 543 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 39 180 8.0E-33 T 06-07-2017 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK77_RS17195 75f727098ab66068affb8e35436f4f6f 543 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 477 537 7.1E-10 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK77_RS17195 75f727098ab66068affb8e35436f4f6f 543 Gene3D G3DSA:3.40.120.10 223 307 6.5E-43 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAK77_RS22975 ddf19ccbaaadceceb4bc8bea30217c9b 473 Pfam PF06114 Domain of unknown function (DUF955) 192 315 1.6E-16 T 06-07-2017 IPR010359 HTH domain, IrrE-type CAK77_RS22975 ddf19ccbaaadceceb4bc8bea30217c9b 473 Pfam PF09856 Predicted transcriptional regulator (DUF2083) 316 472 3.5E-67 T 06-07-2017 IPR018653 Domain of unknown function DUF2083,transcriptional regulator CAK77_RS22975 ddf19ccbaaadceceb4bc8bea30217c9b 473 SMART SM00530 9 64 6.9E-15 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAK77_RS22975 ddf19ccbaaadceceb4bc8bea30217c9b 473 Pfam PF13560 Helix-turn-helix domain 7 61 8.5E-13 T 06-07-2017 CAK77_RS22975 ddf19ccbaaadceceb4bc8bea30217c9b 473 Gene3D G3DSA:1.10.260.40 6 73 3.0E-19 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK77_RS22975 ddf19ccbaaadceceb4bc8bea30217c9b 473 SUPERFAMILY SSF47413 5 67 7.51E-15 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK77_RS22975 ddf19ccbaaadceceb4bc8bea30217c9b 473 PIRSF PIRSF019251 1 473 4.9E-168 T 06-07-2017 IPR026281 HTH-type transcriptional regulator RamB GO:0006355 CAK77_RS17235 68a1f282baeaa3a226798e531de4d3e1 302 Gene3D G3DSA:3.40.190.10 99 183 5.8E-15 T 06-07-2017 CAK77_RS17235 68a1f282baeaa3a226798e531de4d3e1 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 13 68 6.0E-17 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK77_RS17235 68a1f282baeaa3a226798e531de4d3e1 302 Gene3D G3DSA:3.40.190.10 184 267 1.2E-16 T 06-07-2017 CAK77_RS17235 68a1f282baeaa3a226798e531de4d3e1 302 SUPERFAMILY SSF46785 9 116 1.32E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS17235 68a1f282baeaa3a226798e531de4d3e1 302 SUPERFAMILY SSF53850 96 298 1.28E-37 T 06-07-2017 CAK77_RS17235 68a1f282baeaa3a226798e531de4d3e1 302 Pfam PF03466 LysR substrate binding domain 96 298 4.1E-42 T 06-07-2017 IPR005119 LysR, substrate-binding CAK77_RS17235 68a1f282baeaa3a226798e531de4d3e1 302 Gene3D G3DSA:1.10.10.10 10 93 9.5E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS21055 420520f66bb6573a2b2a3a7dbf3d1c11 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 4.0E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS21055 420520f66bb6573a2b2a3a7dbf3d1c11 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 38 4.0E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS21055 420520f66bb6573a2b2a3a7dbf3d1c11 205 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 69 3.5E-12 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS21055 420520f66bb6573a2b2a3a7dbf3d1c11 205 Gene3D G3DSA:1.10.357.10 23 198 5.9E-28 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS21055 420520f66bb6573a2b2a3a7dbf3d1c11 205 SUPERFAMILY SSF46689 16 87 2.99E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS00255 388b07c23d1ec5aa7040535d21a273aa 288 Gene3D G3DSA:3.40.50.1820 13 283 1.6E-33 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS00255 388b07c23d1ec5aa7040535d21a273aa 288 Pfam PF12697 Alpha/beta hydrolase family 32 276 1.5E-17 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS00255 388b07c23d1ec5aa7040535d21a273aa 288 SUPERFAMILY SSF53474 14 283 1.56E-35 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS03675 0b8cd78fd1f291540bca2513a8b66932 438 ProDom PD092006 MEMBRANE YWOB TRANSMEMBRANE 126 224 7.0E-33 T 06-07-2017 IPR020218 Uncharacterised protein family, YwoB, transmembrane CAK77_RS11115 3f15b7887f475f38413574d917b63207 328 SUPERFAMILY SSF55729 289 300 3.47E-11 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS11115 3f15b7887f475f38413574d917b63207 328 SUPERFAMILY SSF55729 126 259 3.47E-11 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS11115 3f15b7887f475f38413574d917b63207 328 Gene3D G3DSA:3.40.630.30 140 217 8.5E-5 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS11115 3f15b7887f475f38413574d917b63207 328 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 17 309 3.8E-59 T 06-07-2017 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal CAK77_RS07005 37d1704e896b2f9fd45844bc67177a02 419 Gene3D G3DSA:3.90.230.10 168 398 1.1E-19 T 06-07-2017 IPR000994 Peptidase M24, structural domain CAK77_RS07005 37d1704e896b2f9fd45844bc67177a02 419 Gene3D G3DSA:3.40.350.10 7 158 4.9E-4 T 06-07-2017 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal CAK77_RS07005 37d1704e896b2f9fd45844bc67177a02 419 Pfam PF00557 Metallopeptidase family M24 176 396 8.9E-14 T 06-07-2017 IPR000994 Peptidase M24, structural domain CAK77_RS07005 37d1704e896b2f9fd45844bc67177a02 419 SUPERFAMILY SSF55920 167 400 1.31E-24 T 06-07-2017 IPR000994 Peptidase M24, structural domain CAK77_RS07800 01137489b9024b113d1f071d01c2e925 399 PIRSF PIRSF029347 1 399 1.6E-124 T 06-07-2017 IPR014555 RecF-like CAK77_RS07800 01137489b9024b113d1f071d01c2e925 399 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 23 344 2.4E-27 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 CAK77_RS07800 01137489b9024b113d1f071d01c2e925 399 SUPERFAMILY SSF52540 2 349 4.28E-25 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS07800 01137489b9024b113d1f071d01c2e925 399 Gene3D G3DSA:3.40.50.300 2 107 3.5E-29 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS07800 01137489b9024b113d1f071d01c2e925 399 Gene3D G3DSA:3.40.50.300 157 348 3.5E-29 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS10770 9c3d00355aac44cd835a0357e73a8e04 1002 Pfam PF03176 MMPL family 692 987 1.9E-68 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 CAK77_RS10770 9c3d00355aac44cd835a0357e73a8e04 1002 Pfam PF03176 MMPL family 101 429 5.6E-88 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 CAK77_RS10770 9c3d00355aac44cd835a0357e73a8e04 1002 Gene3D G3DSA:1.20.1640.10 811 985 4.5E-16 T 06-07-2017 CAK77_RS10770 9c3d00355aac44cd835a0357e73a8e04 1002 Gene3D G3DSA:1.20.1640.10 201 400 1.7E-26 T 06-07-2017 CAK77_RS10770 9c3d00355aac44cd835a0357e73a8e04 1002 SUPERFAMILY SSF82866 186 397 1.01E-25 T 06-07-2017 CAK77_RS10770 9c3d00355aac44cd835a0357e73a8e04 1002 SUPERFAMILY SSF82866 777 985 5.1E-25 T 06-07-2017 CAK77_RS21570 8663c2a2e53b7654105adc1f98ad7b0d 120 SUPERFAMILY SSF46785 4 116 3.3E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS21570 8663c2a2e53b7654105adc1f98ad7b0d 120 Gene3D G3DSA:1.10.10.10 3 79 1.9E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS21570 8663c2a2e53b7654105adc1f98ad7b0d 120 Pfam PF03965 Penicillinase repressor 7 115 1.4E-25 T 06-07-2017 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 CAK77_RS24035 c9e842959e74b35375619082cbf7f659 462 SUPERFAMILY SSF54373 296 399 3.99E-24 T 06-07-2017 CAK77_RS24035 c9e842959e74b35375619082cbf7f659 462 Gene3D G3DSA:3.50.50.60 13 93 2.8E-56 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS24035 c9e842959e74b35375619082cbf7f659 462 Gene3D G3DSA:3.50.50.60 410 453 2.8E-56 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS24035 c9e842959e74b35375619082cbf7f659 462 Gene3D G3DSA:3.50.50.60 216 313 2.8E-56 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS24035 c9e842959e74b35375619082cbf7f659 462 Gene3D G3DSA:1.10.405.10 116 206 4.1E-25 T 06-07-2017 CAK77_RS24035 c9e842959e74b35375619082cbf7f659 462 SUPERFAMILY SSF51905 14 315 2.59E-67 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS24035 c9e842959e74b35375619082cbf7f659 462 SUPERFAMILY SSF51905 414 452 2.59E-67 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS24035 c9e842959e74b35375619082cbf7f659 462 Pfam PF01593 Flavin containing amine oxidoreductase 23 450 1.4E-68 T 06-07-2017 IPR002937 Amine oxidase GO:0016491|GO:0055114 CAK77_RS24035 c9e842959e74b35375619082cbf7f659 462 PRINTS PR00757 Flavin-containing amine oxidase signature 300 319 3.4E-20 T 06-07-2017 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 CAK77_RS24035 c9e842959e74b35375619082cbf7f659 462 PRINTS PR00757 Flavin-containing amine oxidase signature 432 449 3.4E-20 T 06-07-2017 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 CAK77_RS24035 c9e842959e74b35375619082cbf7f659 462 PRINTS PR00757 Flavin-containing amine oxidase signature 401 423 3.4E-20 T 06-07-2017 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 CAK77_RS24035 c9e842959e74b35375619082cbf7f659 462 PRINTS PR00757 Flavin-containing amine oxidase signature 204 226 3.4E-20 T 06-07-2017 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 CAK77_RS24035 c9e842959e74b35375619082cbf7f659 462 PRINTS PR00757 Flavin-containing amine oxidase signature 15 34 3.4E-20 T 06-07-2017 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 CAK77_RS24035 c9e842959e74b35375619082cbf7f659 462 PRINTS PR00757 Flavin-containing amine oxidase signature 181 202 3.4E-20 T 06-07-2017 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 CAK77_RS24035 c9e842959e74b35375619082cbf7f659 462 PRINTS PR00757 Flavin-containing amine oxidase signature 100 122 3.4E-20 T 06-07-2017 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 CAK77_RS13585 4a11eee1e78b6663f377c63ea098f898 340 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 159 2.6E-54 T 06-07-2017 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK77_RS13585 4a11eee1e78b6663f377c63ea098f898 340 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 157 164 - T 06-07-2017 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK77_RS13585 4a11eee1e78b6663f377c63ea098f898 340 Gene3D G3DSA:3.40.50.720 2 167 1.2E-68 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS13585 4a11eee1e78b6663f377c63ea098f898 340 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 276 291 6.7E-38 T 06-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK77_RS13585 4a11eee1e78b6663f377c63ea098f898 340 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 180 196 6.7E-38 T 06-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK77_RS13585 4a11eee1e78b6663f377c63ea098f898 340 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 117 130 6.7E-38 T 06-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK77_RS13585 4a11eee1e78b6663f377c63ea098f898 340 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 236 253 6.7E-38 T 06-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK77_RS13585 4a11eee1e78b6663f377c63ea098f898 340 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 153 171 6.7E-38 T 06-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK77_RS13585 4a11eee1e78b6663f377c63ea098f898 340 SMART SM00846 3 159 7.5E-86 T 06-07-2017 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK77_RS13585 4a11eee1e78b6663f377c63ea098f898 340 SUPERFAMILY SSF51735 2 158 4.6E-57 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS13585 4a11eee1e78b6663f377c63ea098f898 340 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 164 319 4.2E-70 T 06-07-2017 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK77_RS13585 4a11eee1e78b6663f377c63ea098f898 340 Gene3D G3DSA:3.30.360.10 168 321 5.5E-76 T 06-07-2017 CAK77_RS13585 4a11eee1e78b6663f377c63ea098f898 340 SUPERFAMILY SSF55347 158 319 8.04E-73 T 06-07-2017 CAK77_RS13585 4a11eee1e78b6663f377c63ea098f898 340 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 331 7.4E-134 T 06-07-2017 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK77_RS13585 4a11eee1e78b6663f377c63ea098f898 340 PIRSF PIRSF000149 1 339 5.6E-131 T 06-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAK77_RS12565 b38e0a2604eda63dc600c39e22dd0b55 154 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 2 146 4.6E-14 T 06-07-2017 IPR019587 Polyketide cyclase/dehydrase CAK77_RS12565 b38e0a2604eda63dc600c39e22dd0b55 154 SUPERFAMILY SSF55961 1 147 7.86E-15 T 06-07-2017 CAK77_RS12565 b38e0a2604eda63dc600c39e22dd0b55 154 Gene3D G3DSA:3.30.530.20 1 146 1.0E-4 T 06-07-2017 IPR023393 START-like domain CAK77_RS14175 4e8bcbf1eee799bc6fce3d0139f84fe3 182 Gene3D G3DSA:3.30.428.10 39 180 9.7E-40 T 06-07-2017 IPR011146 HIT-like domain GO:0003824 CAK77_RS14175 4e8bcbf1eee799bc6fce3d0139f84fe3 182 SUPERFAMILY SSF54197 20 179 1.52E-38 T 06-07-2017 IPR011146 HIT-like domain GO:0003824 CAK77_RS14175 4e8bcbf1eee799bc6fce3d0139f84fe3 182 Pfam PF01230 HIT domain 56 146 1.4E-14 T 06-07-2017 IPR001310 Histidine triad (HIT) protein CAK77_RS05965 cf99f2230782cf2824e59e2b3411caf1 382 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 120 214 2.0E-26 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAK77_RS05965 cf99f2230782cf2824e59e2b3411caf1 382 Gene3D G3DSA:1.10.540.10 2 117 8.9E-39 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS05965 cf99f2230782cf2824e59e2b3411caf1 382 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 334 353 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CAK77_RS05965 cf99f2230782cf2824e59e2b3411caf1 382 Gene3D G3DSA:1.20.140.10 216 378 4.4E-66 T 06-07-2017 CAK77_RS05965 cf99f2230782cf2824e59e2b3411caf1 382 SUPERFAMILY SSF56645 2 239 6.68E-81 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK77_RS05965 cf99f2230782cf2824e59e2b3411caf1 382 SUPERFAMILY SSF47203 224 377 6.28E-54 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS05965 cf99f2230782cf2824e59e2b3411caf1 382 Gene3D G3DSA:2.40.110.10 119 215 1.6E-39 T 06-07-2017 CAK77_RS05965 cf99f2230782cf2824e59e2b3411caf1 382 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 5 116 4.0E-29 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS05965 cf99f2230782cf2824e59e2b3411caf1 382 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 228 375 3.2E-47 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS10980 0a387f40898098c059ac220ebf2f5785 114 SUPERFAMILY SSF54593 6 111 1.41E-14 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK77_RS10980 0a387f40898098c059ac220ebf2f5785 114 Gene3D G3DSA:3.10.180.10 6 112 2.9E-15 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK77_RS15930 253bae13fef1a0318883277ea951f6e5 976 SUPERFAMILY SSF82866 734 943 1.96E-28 T 06-07-2017 CAK77_RS15930 253bae13fef1a0318883277ea951f6e5 976 Pfam PF03176 MMPL family 68 396 6.3E-91 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 CAK77_RS15930 253bae13fef1a0318883277ea951f6e5 976 Pfam PF03176 MMPL family 682 945 1.1E-71 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 CAK77_RS15930 253bae13fef1a0318883277ea951f6e5 976 SUPERFAMILY SSF82866 147 364 2.49E-20 T 06-07-2017 CAK77_RS15930 253bae13fef1a0318883277ea951f6e5 976 Gene3D G3DSA:1.20.1640.10 755 943 1.8E-22 T 06-07-2017 CAK77_RS15930 253bae13fef1a0318883277ea951f6e5 976 Gene3D G3DSA:1.20.1640.10 168 373 2.0E-21 T 06-07-2017 CAK77_RS16550 91c67ff0149c154bcfe86a44064d43ba 156 Gene3D G3DSA:1.10.10.10 10 149 8.3E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS16550 91c67ff0149c154bcfe86a44064d43ba 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 94 110 1.9E-5 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK77_RS16550 91c67ff0149c154bcfe86a44064d43ba 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 124 144 1.9E-5 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK77_RS16550 91c67ff0149c154bcfe86a44064d43ba 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 75 90 1.9E-5 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK77_RS16550 91c67ff0149c154bcfe86a44064d43ba 156 SMART SM00347 34 134 5.5E-13 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK77_RS16550 91c67ff0149c154bcfe86a44064d43ba 156 SUPERFAMILY SSF46785 31 151 1.77E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS16550 91c67ff0149c154bcfe86a44064d43ba 156 Pfam PF01047 MarR family 42 99 2.4E-12 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK77_RS11680 090174b4f679abdb82084030d3bc1873 207 Pfam PF13411 MerR HTH family regulatory protein 51 116 6.6E-13 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAK77_RS11680 090174b4f679abdb82084030d3bc1873 207 SUPERFAMILY SSF46955 52 134 9.16E-14 T 06-07-2017 IPR009061 Putative DNA-binding domain CAK77_RS11680 090174b4f679abdb82084030d3bc1873 207 SMART SM00422 47 119 1.3E-18 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAK77_RS11680 090174b4f679abdb82084030d3bc1873 207 Gene3D G3DSA:1.10.1660.10 52 123 4.6E-12 T 06-07-2017 CAK77_RS15010 82ad054f1aef4cae0cf9b5c8af9ccfa6 225 Gene3D G3DSA:3.10.180.10 1 118 1.6E-12 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK77_RS15010 82ad054f1aef4cae0cf9b5c8af9ccfa6 225 SUPERFAMILY SSF54593 2 164 7.66E-13 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK77_RS22230 2c366c12dd45c591b45f7d0c17845851 375 SUPERFAMILY SSF51445 58 369 6.74E-61 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily CAK77_RS22230 2c366c12dd45c591b45f7d0c17845851 375 Gene3D G3DSA:3.20.20.300 57 369 7.3E-75 T 06-07-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CAK77_RS22230 2c366c12dd45c591b45f7d0c17845851 375 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 52 366 8.4E-82 T 06-07-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CAK77_RS11060 d484ac9822b9e5538ed6faaadb59c405 767 SUPERFAMILY SSF82866 133 348 2.22E-31 T 06-07-2017 CAK77_RS11060 d484ac9822b9e5538ed6faaadb59c405 767 Gene3D G3DSA:1.20.1640.10 148 350 9.3E-27 T 06-07-2017 CAK77_RS11060 d484ac9822b9e5538ed6faaadb59c405 767 Gene3D G3DSA:1.20.1640.10 543 734 6.2E-25 T 06-07-2017 CAK77_RS11060 d484ac9822b9e5538ed6faaadb59c405 767 SUPERFAMILY SSF82866 556 731 2.22E-22 T 06-07-2017 CAK77_RS11060 d484ac9822b9e5538ed6faaadb59c405 767 Pfam PF03176 MMPL family 58 390 1.5E-39 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 CAK77_RS11060 d484ac9822b9e5538ed6faaadb59c405 767 Pfam PF03176 MMPL family 452 748 1.8E-29 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 CAK77_RS10970 77edd5660dd235175ddaa6942e0e9fdc 75 SMART SM00923 9 59 1.9E-26 T 06-07-2017 IPR005153 MbtH-like protein CAK77_RS10970 77edd5660dd235175ddaa6942e0e9fdc 75 Pfam PF03621 MbtH-like protein 7 58 1.3E-26 T 06-07-2017 IPR005153 MbtH-like protein CAK77_RS10970 77edd5660dd235175ddaa6942e0e9fdc 75 Gene3D G3DSA:3.90.820.10 17 74 5.0E-29 T 06-07-2017 CAK77_RS10970 77edd5660dd235175ddaa6942e0e9fdc 75 SUPERFAMILY SSF160582 8 74 8.89E-29 T 06-07-2017 CAK77_RS17590 3d0463469c5c978a6f62fc0d3fd14d3b 90 Gene3D G3DSA:3.40.30.10 16 89 2.2E-17 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK77_RS17590 3d0463469c5c978a6f62fc0d3fd14d3b 90 ProSitePatterns PS00194 Thioredoxin family active site. 15 33 - T 06-07-2017 IPR017937 Thioredoxin, conserved site GO:0045454 CAK77_RS17590 3d0463469c5c978a6f62fc0d3fd14d3b 90 TIGRFAM TIGR02200 GlrX_actino: glutaredoxin-like protein 17 88 2.2E-34 T 06-07-2017 IPR011915 Glutaredoxin-like protein, actinobacteria CAK77_RS17590 3d0463469c5c978a6f62fc0d3fd14d3b 90 Pfam PF00462 Glutaredoxin 16 70 8.0E-12 T 06-07-2017 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 CAK77_RS17590 3d0463469c5c978a6f62fc0d3fd14d3b 90 SUPERFAMILY SSF52833 15 82 2.8E-15 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK77_RS14400 1fe5350490abb2caa0a3d9758fadf682 223 SMART SM00749 14 77 6.6 T 06-07-2017 IPR014004 Transport-associated and nodulation domain, bacteria CAK77_RS14400 1fe5350490abb2caa0a3d9758fadf682 223 SMART SM00749 85 150 60.0 T 06-07-2017 IPR014004 Transport-associated and nodulation domain, bacteria CAK77_RS14400 1fe5350490abb2caa0a3d9758fadf682 223 SMART SM00749 159 222 2.7E-5 T 06-07-2017 IPR014004 Transport-associated and nodulation domain, bacteria CAK77_RS14400 1fe5350490abb2caa0a3d9758fadf682 223 Pfam PF04972 BON domain 9 76 8.6E-15 T 06-07-2017 IPR007055 BON domain CAK77_RS14400 1fe5350490abb2caa0a3d9758fadf682 223 Pfam PF04972 BON domain 85 150 1.1E-12 T 06-07-2017 IPR007055 BON domain CAK77_RS14400 1fe5350490abb2caa0a3d9758fadf682 223 Pfam PF04972 BON domain 156 221 2.2E-15 T 06-07-2017 IPR007055 BON domain CAK77_RS07085 958afc513e6a1793102a0af79cecc295 631 Pfam PF00664 ABC transporter transmembrane region 42 351 1.0E-58 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAK77_RS07085 958afc513e6a1793102a0af79cecc295 631 SMART SM00382 422 608 7.5E-17 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS07085 958afc513e6a1793102a0af79cecc295 631 SUPERFAMILY SSF90123 105 382 4.32E-75 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAK77_RS07085 958afc513e6a1793102a0af79cecc295 631 SUPERFAMILY SSF90123 27 65 4.32E-75 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAK77_RS07085 958afc513e6a1793102a0af79cecc295 631 Gene3D G3DSA:3.40.50.300 397 628 2.5E-79 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS07085 958afc513e6a1793102a0af79cecc295 631 Pfam PF00005 ABC transporter 414 562 9.7E-31 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK77_RS07085 958afc513e6a1793102a0af79cecc295 631 Gene3D G3DSA:1.20.1560.10 28 382 4.2E-79 T 06-07-2017 CAK77_RS07085 958afc513e6a1793102a0af79cecc295 631 SUPERFAMILY SSF52540 392 630 2.11E-88 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS07085 958afc513e6a1793102a0af79cecc295 631 ProSitePatterns PS00211 ABC transporters family signature. 534 548 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK77_RS13065 5623be10b0ff7b410ad8e71425b9e5c3 271 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 215 229 - T 06-07-2017 IPR020550 Inositol monophosphatase, conserved site GO:0046854 CAK77_RS13065 5623be10b0ff7b410ad8e71425b9e5c3 271 Pfam PF00459 Inositol monophosphatase family 7 262 6.2E-46 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAK77_RS13065 5623be10b0ff7b410ad8e71425b9e5c3 271 SUPERFAMILY SSF56655 13 263 1.7E-59 T 06-07-2017 CAK77_RS13065 5623be10b0ff7b410ad8e71425b9e5c3 271 Gene3D G3DSA:3.30.540.10 8 152 8.6E-32 T 06-07-2017 CAK77_RS13065 5623be10b0ff7b410ad8e71425b9e5c3 271 Gene3D G3DSA:3.40.190.80 153 264 1.2E-23 T 06-07-2017 CAK77_RS13065 5623be10b0ff7b410ad8e71425b9e5c3 271 PRINTS PR00377 Inositol monophosphatase superfamily signature 212 236 3.5E-23 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAK77_RS13065 5623be10b0ff7b410ad8e71425b9e5c3 271 PRINTS PR00377 Inositol monophosphatase superfamily signature 181 202 3.5E-23 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAK77_RS13065 5623be10b0ff7b410ad8e71425b9e5c3 271 PRINTS PR00377 Inositol monophosphatase superfamily signature 41 61 3.5E-23 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAK77_RS13065 5623be10b0ff7b410ad8e71425b9e5c3 271 PRINTS PR00377 Inositol monophosphatase superfamily signature 82 98 3.5E-23 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAK77_RS21795 4337f41706d9fc25019dc883d5c29e72 195 SUPERFAMILY SSF54593 15 169 2.28E-26 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK77_RS21795 4337f41706d9fc25019dc883d5c29e72 195 Gene3D G3DSA:3.10.180.10 2 176 1.6E-40 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK77_RS21795 4337f41706d9fc25019dc883d5c29e72 195 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 17 165 1.4E-20 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CAK77_RS06125 0e5e2be989207a23f284d221ba6f3867 288 Gene3D G3DSA:3.40.50.720 7 162 2.3E-40 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS06125 0e5e2be989207a23f284d221ba6f3867 288 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 10 23 - T 06-07-2017 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 CAK77_RS06125 0e5e2be989207a23f284d221ba6f3867 288 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 7 161 4.3E-40 T 06-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CAK77_RS06125 0e5e2be989207a23f284d221ba6f3867 288 PIRSF PIRSF000103 1 286 2.7E-65 T 06-07-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CAK77_RS06125 0e5e2be989207a23f284d221ba6f3867 288 SUPERFAMILY SSF51735 6 162 1.72E-37 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS06125 0e5e2be989207a23f284d221ba6f3867 288 SUPERFAMILY SSF48179 164 282 1.59E-14 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAK77_RS06125 0e5e2be989207a23f284d221ba6f3867 288 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 165 275 8.6E-10 T 06-07-2017 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 CAK77_RS06125 0e5e2be989207a23f284d221ba6f3867 288 Gene3D G3DSA:1.10.1040.10 165 281 8.0E-17 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAK77_RS00285 6b4a91d7f1317a1493f327a4154c0101 134 Hamap MF_00927 Cell wall synthesis protein CwsA [cwsA]. 9 134 19.78 T 06-07-2017 IPR024245 Cell wall synthesis protein CwsA CAK77_RS00285 6b4a91d7f1317a1493f327a4154c0101 134 ProDom PD070500 MEMBRANE TRANSMEMBRANE MB0008C RV0008C/MT0010 13 94 7.0E-5 T 06-07-2017 IPR024245 Cell wall synthesis protein CwsA CAK77_RS00285 6b4a91d7f1317a1493f327a4154c0101 134 Pfam PF10814 Protein of unknown function (DUF2562) 14 134 1.6E-23 T 06-07-2017 IPR024245 Cell wall synthesis protein CwsA CAK77_RS19175 52b3c9f7059ad821d946d1b81f3fb707 491 Pfam PF13520 Amino acid permease 36 447 4.2E-55 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CAK77_RS19175 52b3c9f7059ad821d946d1b81f3fb707 491 PIRSF PIRSF006060 20 489 8.0E-88 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CAK77_RS13235 d6ca2d6581caa60333720eb5701a0522 325 Gene3D G3DSA:3.40.50.40 212 318 3.5E-24 T 06-07-2017 IPR027473 L-asparaginase, C-terminal domain Reactome: R-HSA-70614 CAK77_RS13235 d6ca2d6581caa60333720eb5701a0522 325 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 90 100 - T 06-07-2017 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 CAK77_RS13235 d6ca2d6581caa60333720eb5701a0522 325 SUPERFAMILY SSF53774 13 322 1.7E-78 T 06-07-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 CAK77_RS13235 d6ca2d6581caa60333720eb5701a0522 325 PRINTS PR00139 Asparaginase/glutaminase family signature 89 107 4.6E-15 T 06-07-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 CAK77_RS13235 d6ca2d6581caa60333720eb5701a0522 325 PRINTS PR00139 Asparaginase/glutaminase family signature 259 277 4.6E-15 T 06-07-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 CAK77_RS13235 d6ca2d6581caa60333720eb5701a0522 325 PRINTS PR00139 Asparaginase/glutaminase family signature 18 29 4.6E-15 T 06-07-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 CAK77_RS13235 d6ca2d6581caa60333720eb5701a0522 325 Gene3D G3DSA:3.40.50.1170 15 194 3.6E-47 T 06-07-2017 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 CAK77_RS13235 d6ca2d6581caa60333720eb5701a0522 325 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 20 28 - T 06-07-2017 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 CAK77_RS13235 d6ca2d6581caa60333720eb5701a0522 325 SMART SM00870 17 321 6.5E-90 T 06-07-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 CAK77_RS13235 d6ca2d6581caa60333720eb5701a0522 325 Pfam PF00710 Asparaginase, N-terminal 18 186 9.2E-46 T 06-07-2017 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 CAK77_RS13235 d6ca2d6581caa60333720eb5701a0522 325 PIRSF PIRSF001220 12 324 3.5E-77 T 06-07-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 CAK77_RS13235 d6ca2d6581caa60333720eb5701a0522 325 PIRSF PIRSF500176 14 324 8.1E-82 T 06-07-2017 CAK77_RS07665 9ff066168963eda5ae63cc19e1ac839c 218 Gene3D G3DSA:1.10.10.10 123 216 4.6E-32 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS07665 9ff066168963eda5ae63cc19e1ac839c 218 Pfam PF00072 Response regulator receiver domain 8 118 2.1E-25 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK77_RS07665 9ff066168963eda5ae63cc19e1ac839c 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 1.0E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK77_RS07665 9ff066168963eda5ae63cc19e1ac839c 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 1.0E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK77_RS07665 9ff066168963eda5ae63cc19e1ac839c 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 1.0E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK77_RS07665 9ff066168963eda5ae63cc19e1ac839c 218 SMART SM00421 152 209 2.7E-23 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK77_RS07665 9ff066168963eda5ae63cc19e1ac839c 218 SUPERFAMILY SSF52172 7 137 4.13E-31 T 06-07-2017 IPR011006 CheY-like superfamily CAK77_RS07665 9ff066168963eda5ae63cc19e1ac839c 218 ProSitePatterns PS00622 LuxR-type HTH domain signature. 169 196 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK77_RS07665 9ff066168963eda5ae63cc19e1ac839c 218 Gene3D G3DSA:3.40.50.2300 8 122 2.8E-33 T 06-07-2017 CAK77_RS07665 9ff066168963eda5ae63cc19e1ac839c 218 SUPERFAMILY SSF46894 144 215 1.26E-21 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAK77_RS07665 9ff066168963eda5ae63cc19e1ac839c 218 SMART SM00448 6 118 8.3E-27 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK77_RS07665 9ff066168963eda5ae63cc19e1ac839c 218 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 209 1.2E-18 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK77_RS15605 51a709dfa693ff5160d791d285506656 157 SUPERFAMILY SSF47240 12 151 7.39E-42 T 06-07-2017 IPR009078 Ferritin-like superfamily CAK77_RS15605 51a709dfa693ff5160d791d285506656 157 Pfam PF14530 Domain of unknown function (DUF4439) 18 155 3.0E-43 T 06-07-2017 IPR029447 Domain of unknown function DUF4439 CAK77_RS15605 51a709dfa693ff5160d791d285506656 157 Gene3D G3DSA:1.20.1260.10 12 142 1.2E-43 T 06-07-2017 IPR012347 Ferritin-related CAK77_RS21965 362270f71439218b2599cf4d0da62f68 322 Pfam PF03405 Fatty acid desaturase 7 313 2.5E-78 T 06-07-2017 IPR005067 Fatty acid desaturase, type 2 GO:0006631|GO:0045300|GO:0055114 CAK77_RS21965 362270f71439218b2599cf4d0da62f68 322 SUPERFAMILY SSF47240 1 309 2.31E-83 T 06-07-2017 IPR009078 Ferritin-like superfamily CAK77_RS21965 362270f71439218b2599cf4d0da62f68 322 Gene3D G3DSA:1.10.620.20 2 310 1.7E-108 T 06-07-2017 IPR012348 Ribonucleotide reductase-related GO:0016491|GO:0055114 Reactome: R-HSA-499943 CAK77_RS21965 362270f71439218b2599cf4d0da62f68 322 PIRSF PIRSF000346 1 319 1.2E-93 T 06-07-2017 IPR005067 Fatty acid desaturase, type 2 GO:0006631|GO:0045300|GO:0055114 CAK77_RS04100 0b0ff67d7f187f00fa8413d8fa305492 152 Pfam PF10027 Predicted integral membrane protein (DUF2269) 4 146 1.3E-7 T 06-07-2017 IPR018729 Protein of unknown function DUF2269, transmembrane CAK77_RS23915 977c6eac2bfc7dc3f5f3ccdd98fdbd2d 489 Gene3D G3DSA:3.40.710.10 44 370 1.2E-89 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK77_RS23915 977c6eac2bfc7dc3f5f3ccdd98fdbd2d 489 Gene3D G3DSA:3.40.710.10 402 467 1.2E-89 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK77_RS23915 977c6eac2bfc7dc3f5f3ccdd98fdbd2d 489 SUPERFAMILY SSF56601 45 370 2.02E-80 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK77_RS23915 977c6eac2bfc7dc3f5f3ccdd98fdbd2d 489 SUPERFAMILY SSF56601 403 465 2.02E-80 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK77_RS23915 977c6eac2bfc7dc3f5f3ccdd98fdbd2d 489 Pfam PF00144 Beta-lactamase 50 459 1.8E-61 T 06-07-2017 IPR001466 Beta-lactamase-related CAK77_RS03925 18f68739d5d27a044208786f91e09fd9 284 Pfam PF01063 Amino-transferase class IV 33 258 3.5E-44 T 06-07-2017 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CAK77_RS03925 18f68739d5d27a044208786f91e09fd9 284 Gene3D G3DSA:3.30.470.10 7 105 1.9E-19 T 06-07-2017 CAK77_RS03925 18f68739d5d27a044208786f91e09fd9 284 SUPERFAMILY SSF56752 7 277 2.09E-51 T 06-07-2017 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CAK77_RS03925 18f68739d5d27a044208786f91e09fd9 284 Gene3D G3DSA:3.20.10.10 123 279 2.1E-28 T 06-07-2017 CAK77_RS07925 1a969d652b277acc304e471bad3292f6 864 Pfam PF01433 Peptidase family M1 18 388 8.0E-76 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CAK77_RS07925 1a969d652b277acc304e471bad3292f6 864 SUPERFAMILY SSF63737 5 196 5.89E-45 T 06-07-2017 CAK77_RS07925 1a969d652b277acc304e471bad3292f6 864 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 179 194 5.7E-25 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CAK77_RS07925 1a969d652b277acc304e471bad3292f6 864 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 262 272 5.7E-25 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CAK77_RS07925 1a969d652b277acc304e471bad3292f6 864 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 296 311 5.7E-25 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CAK77_RS07925 1a969d652b277acc304e471bad3292f6 864 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 315 327 5.7E-25 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CAK77_RS07925 1a969d652b277acc304e471bad3292f6 864 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 136 151 5.7E-25 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CAK77_RS07925 1a969d652b277acc304e471bad3292f6 864 Gene3D G3DSA:1.10.390.10 309 456 7.9E-43 T 06-07-2017 CAK77_RS07925 1a969d652b277acc304e471bad3292f6 864 SUPERFAMILY SSF55486 209 455 1.07E-76 T 06-07-2017 CAK77_RS07925 1a969d652b277acc304e471bad3292f6 864 TIGRFAM TIGR02412 pepN_strep_liv: aminopeptidase N 5 860 1.2E-300 T 06-07-2017 IPR012778 Peptidase M1, aminopeptidase GO:0004177|GO:0006508 KEGG: 00480+3.4.11.2|MetaCyc: PWY-4061|MetaCyc: PWY-6842|MetaCyc: PWY-7112 CAK77_RS07925 1a969d652b277acc304e471bad3292f6 864 Pfam PF11838 ERAP1-like C-terminal domain 537 852 6.1E-60 T 06-07-2017 IPR024571 ERAP1-like C-terminal domain CAK77_RS16535 8b07ba1f66d88beb530a75bd16654cba 461 Gene3D G3DSA:3.40.640.10 72 346 4.4E-85 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK77_RS16535 8b07ba1f66d88beb530a75bd16654cba 461 Pfam PF00202 Aminotransferase class-III 36 451 4.8E-100 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAK77_RS16535 8b07ba1f66d88beb530a75bd16654cba 461 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 259 296 - T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAK77_RS16535 8b07ba1f66d88beb530a75bd16654cba 461 Gene3D G3DSA:3.90.1150.10 13 70 2.3E-31 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK77_RS16535 8b07ba1f66d88beb530a75bd16654cba 461 Gene3D G3DSA:3.90.1150.10 348 456 2.3E-31 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK77_RS16535 8b07ba1f66d88beb530a75bd16654cba 461 SUPERFAMILY SSF53383 28 456 7.43E-122 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK77_RS21045 bfd6b0ac4c893d1ca8b3ce37c4eb7ea1 393 SUPERFAMILY SSF51905 1 300 6.0E-30 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS21045 bfd6b0ac4c893d1ca8b3ce37c4eb7ea1 393 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 272 4.7E-37 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS21045 bfd6b0ac4c893d1ca8b3ce37c4eb7ea1 393 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 7 29 1.9E-7 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAK77_RS21045 bfd6b0ac4c893d1ca8b3ce37c4eb7ea1 393 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 196 212 1.9E-7 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAK77_RS21045 bfd6b0ac4c893d1ca8b3ce37c4eb7ea1 393 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 97 105 1.9E-7 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAK77_RS21045 bfd6b0ac4c893d1ca8b3ce37c4eb7ea1 393 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 140 164 1.9E-7 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAK77_RS21045 bfd6b0ac4c893d1ca8b3ce37c4eb7ea1 393 Gene3D G3DSA:3.50.50.60 158 299 1.4E-18 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS21045 bfd6b0ac4c893d1ca8b3ce37c4eb7ea1 393 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 6.8E-8 T 06-07-2017 CAK77_RS21045 bfd6b0ac4c893d1ca8b3ce37c4eb7ea1 393 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 144 162 6.8E-8 T 06-07-2017 CAK77_RS21045 bfd6b0ac4c893d1ca8b3ce37c4eb7ea1 393 Gene3D G3DSA:3.50.50.60 6 157 3.3E-23 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS14815 5baf052abab00fd72acf6acdb9bce65c 137 Gene3D G3DSA:2.170.150.20 6 136 6.1E-59 T 06-07-2017 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 CAK77_RS14815 5baf052abab00fd72acf6acdb9bce65c 137 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 12 136 1.4E-47 T 06-07-2017 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 CAK77_RS14815 5baf052abab00fd72acf6acdb9bce65c 137 SUPERFAMILY SSF51316 9 136 4.13E-54 T 06-07-2017 IPR011057 Mss4-like CAK77_RS14815 5baf052abab00fd72acf6acdb9bce65c 137 Pfam PF01641 SelR domain 15 135 2.1E-51 T 06-07-2017 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 CAK77_RS16385 40ef3e6f86f23a15a8d0cd8d831b970e 312 SUPERFAMILY SSF55811 34 146 3.11E-28 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAK77_RS16385 40ef3e6f86f23a15a8d0cd8d831b970e 312 Pfam PF00293 NUDIX domain 37 142 3.8E-19 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 CAK77_RS16385 40ef3e6f86f23a15a8d0cd8d831b970e 312 SMART SM00855 151 265 6.0E-10 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 CAK77_RS16385 40ef3e6f86f23a15a8d0cd8d831b970e 312 PRINTS PR00502 NUDIX hydrolase family signature 62 77 4.1E-6 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CAK77_RS16385 40ef3e6f86f23a15a8d0cd8d831b970e 312 PRINTS PR00502 NUDIX hydrolase family signature 48 62 4.1E-6 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CAK77_RS16385 40ef3e6f86f23a15a8d0cd8d831b970e 312 Gene3D G3DSA:3.90.79.10 12 144 6.5E-31 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAK77_RS16385 40ef3e6f86f23a15a8d0cd8d831b970e 312 Gene3D G3DSA:3.40.50.1240 150 296 2.1E-16 T 06-07-2017 IPR029033 Histidine phosphatase superfamily CAK77_RS16385 40ef3e6f86f23a15a8d0cd8d831b970e 312 ProSitePatterns PS00893 Nudix box signature. 53 74 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CAK77_RS16385 40ef3e6f86f23a15a8d0cd8d831b970e 312 SUPERFAMILY SSF53254 149 296 8.35E-19 T 06-07-2017 IPR029033 Histidine phosphatase superfamily CAK77_RS16385 40ef3e6f86f23a15a8d0cd8d831b970e 312 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 152 231 1.0E-10 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 CAK77_RS17660 fcdd0ebce2601537f6c4e9a94f97f3a2 336 Pfam PF11350 Protein of unknown function (DUF3152) 125 334 5.9E-97 T 06-07-2017 IPR022603 Domain of unknown function DUF3152 CAK77_RS17660 fcdd0ebce2601537f6c4e9a94f97f3a2 336 Gene3D G3DSA:3.40.390.10 190 319 6.0E-5 T 06-07-2017 IPR024079 Metallopeptidase, catalytic domain GO:0008237 CAK77_RS17660 fcdd0ebce2601537f6c4e9a94f97f3a2 336 SUPERFAMILY SSF55486 119 333 1.32E-17 T 06-07-2017 CAK77_RS17660 fcdd0ebce2601537f6c4e9a94f97f3a2 336 SMART SM00235 135 318 6.7E-5 T 06-07-2017 IPR006026 Peptidase, metallopeptidase GO:0006508|GO:0008237|GO:0008270 CAK77_RS18950 4d0449883c43e7ba92ae5119a59e3920 132 Pfam PF00410 Ribosomal protein S8 5 132 1.8E-49 T 06-07-2017 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK77_RS18950 4d0449883c43e7ba92ae5119a59e3920 132 Gene3D G3DSA:3.30.1490.10 76 132 2.4E-28 T 06-07-2017 CAK77_RS18950 4d0449883c43e7ba92ae5119a59e3920 132 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 132 31.418 T 06-07-2017 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK77_RS18950 4d0449883c43e7ba92ae5119a59e3920 132 ProSitePatterns PS00053 Ribosomal protein S8 signature. 102 119 - T 06-07-2017 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK77_RS18950 4d0449883c43e7ba92ae5119a59e3920 132 SUPERFAMILY SSF56047 3 132 2.35E-44 T 06-07-2017 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK77_RS18950 4d0449883c43e7ba92ae5119a59e3920 132 Gene3D G3DSA:3.30.1370.30 2 72 1.2E-28 T 06-07-2017 CAK77_RS10565 c6869cf39cce779f8e1a3d1f1a89f25f 498 Pfam PF03136 Pup-ligase protein 3 454 9.1E-181 T 06-07-2017 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 CAK77_RS10565 c6869cf39cce779f8e1a3d1f1a89f25f 498 TIGRFAM TIGR03688 pupylate_PafA2: proteasome accessory factor PafA2 2 485 1.4E-240 T 06-07-2017 IPR022366 Pup deamidase GO:0008233|GO:0016811 CAK77_RS10565 c6869cf39cce779f8e1a3d1f1a89f25f 498 PIRSF PIRSF018077 8 496 1.6E-215 T 06-07-2017 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 CAK77_RS21480 072cf22c771418357696e8aad9230a85 620 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 06-07-2017 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CAK77_RS21480 072cf22c771418357696e8aad9230a85 620 Pfam PF00012 Hsp70 protein 79 585 2.0E-220 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CAK77_RS21480 072cf22c771418357696e8aad9230a85 620 Pfam PF00012 Hsp70 protein 4 78 8.2E-29 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CAK77_RS21480 072cf22c771418357696e8aad9230a85 620 Gene3D G3DSA:1.20.1270.10 507 584 1.8E-23 T 06-07-2017 IPR029048 Heat shock protein 70kD, C-terminal domain Reactome: R-HSA-3371453 CAK77_RS21480 072cf22c771418357696e8aad9230a85 620 SUPERFAMILY SSF53067 3 159 2.75E-59 T 06-07-2017 CAK77_RS21480 072cf22c771418357696e8aad9230a85 620 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 168 181 - T 06-07-2017 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CAK77_RS21480 072cf22c771418357696e8aad9230a85 620 Gene3D G3DSA:3.30.420.40 167 201 1.3E-34 T 06-07-2017 CAK77_RS21480 072cf22c771418357696e8aad9230a85 620 Gene3D G3DSA:3.30.420.40 292 334 1.3E-34 T 06-07-2017 CAK77_RS21480 072cf22c771418357696e8aad9230a85 620 SUPERFAMILY SSF100920 358 514 1.7E-64 T 06-07-2017 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 CAK77_RS21480 072cf22c771418357696e8aad9230a85 620 Gene3D G3DSA:3.30.420.40 4 38 3.7E-58 T 06-07-2017 CAK77_RS21480 072cf22c771418357696e8aad9230a85 620 Gene3D G3DSA:3.30.420.40 101 166 3.7E-58 T 06-07-2017 CAK77_RS21480 072cf22c771418357696e8aad9230a85 620 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 615 36.575 T 06-07-2017 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453 CAK77_RS21480 072cf22c771418357696e8aad9230a85 620 Gene3D G3DSA:3.30.30.30 39 100 8.2E-17 T 06-07-2017 CAK77_RS21480 072cf22c771418357696e8aad9230a85 620 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 4 584 1.2E-276 T 06-07-2017 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453 CAK77_RS21480 072cf22c771418357696e8aad9230a85 620 Gene3D G3DSA:3.90.640.10 202 288 2.2E-28 T 06-07-2017 CAK77_RS21480 072cf22c771418357696e8aad9230a85 620 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 310 324 - T 06-07-2017 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CAK77_RS21480 072cf22c771418357696e8aad9230a85 620 PRINTS PR00301 70kDa heat shock protein signature 339 359 2.6E-76 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CAK77_RS21480 072cf22c771418357696e8aad9230a85 620 PRINTS PR00301 70kDa heat shock protein signature 31 43 2.6E-76 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CAK77_RS21480 072cf22c771418357696e8aad9230a85 620 PRINTS PR00301 70kDa heat shock protein signature 443 459 2.6E-76 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CAK77_RS21480 072cf22c771418357696e8aad9230a85 620 PRINTS PR00301 70kDa heat shock protein signature 362 381 2.6E-76 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CAK77_RS21480 072cf22c771418357696e8aad9230a85 620 PRINTS PR00301 70kDa heat shock protein signature 3 16 2.6E-76 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CAK77_RS21480 072cf22c771418357696e8aad9230a85 620 PRINTS PR00301 70kDa heat shock protein signature 54 62 2.6E-76 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CAK77_RS21480 072cf22c771418357696e8aad9230a85 620 PRINTS PR00301 70kDa heat shock protein signature 114 134 2.6E-76 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CAK77_RS21480 072cf22c771418357696e8aad9230a85 620 PRINTS PR00301 70kDa heat shock protein signature 307 323 2.6E-76 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CAK77_RS21480 072cf22c771418357696e8aad9230a85 620 PRINTS PR00301 70kDa heat shock protein signature 174 184 2.6E-76 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CAK77_RS21480 072cf22c771418357696e8aad9230a85 620 Gene3D G3DSA:2.60.34.10 364 506 6.3E-76 T 06-07-2017 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 CAK77_RS21480 072cf22c771418357696e8aad9230a85 620 SUPERFAMILY SSF100934 481 591 1.44E-14 T 06-07-2017 IPR029048 Heat shock protein 70kD, C-terminal domain Reactome: R-HSA-3371453 CAK77_RS21480 072cf22c771418357696e8aad9230a85 620 SUPERFAMILY SSF53067 162 356 5.0E-65 T 06-07-2017 CAK77_RS03835 4e4410260d4f4c07a3d673df0046bf90 266 Gene3D G3DSA:3.30.870.10 108 176 3.4E-5 T 06-07-2017 CAK77_RS03835 4e4410260d4f4c07a3d673df0046bf90 266 SUPERFAMILY SSF47413 14 73 3.34E-6 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK77_RS03835 4e4410260d4f4c07a3d673df0046bf90 266 Gene3D G3DSA:1.10.260.40 14 73 7.9E-7 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK77_RS03835 4e4410260d4f4c07a3d673df0046bf90 266 SUPERFAMILY SSF56024 74 165 8.48E-6 T 06-07-2017 CAK77_RS03835 4e4410260d4f4c07a3d673df0046bf90 266 SMART SM00530 16 72 1.8E-4 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAK77_RS21460 69e98022327c0a4dc0455b57d3e64428 384 Pfam PF00970 Oxidoreductase FAD-binding domain 147 238 7.4E-15 T 06-07-2017 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 CAK77_RS21460 69e98022327c0a4dc0455b57d3e64428 384 Pfam PF00042 Globin 7 101 2.0E-5 T 06-07-2017 IPR000971 Globin GO:0019825|GO:0020037 CAK77_RS21460 69e98022327c0a4dc0455b57d3e64428 384 PRINTS PR00410 Phenol hydroxylase reductase family signature 248 267 1.2E-10 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 CAK77_RS21460 69e98022327c0a4dc0455b57d3e64428 384 PRINTS PR00410 Phenol hydroxylase reductase family signature 171 183 1.2E-10 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 CAK77_RS21460 69e98022327c0a4dc0455b57d3e64428 384 PRINTS PR00410 Phenol hydroxylase reductase family signature 273 282 1.2E-10 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 CAK77_RS21460 69e98022327c0a4dc0455b57d3e64428 384 Gene3D G3DSA:2.40.30.10 143 237 2.4E-22 T 06-07-2017 CAK77_RS21460 69e98022327c0a4dc0455b57d3e64428 384 Gene3D G3DSA:3.40.50.80 244 382 1.2E-23 T 06-07-2017 CAK77_RS21460 69e98022327c0a4dc0455b57d3e64428 384 SUPERFAMILY SSF63380 143 237 2.15E-21 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CAK77_RS21460 69e98022327c0a4dc0455b57d3e64428 384 SUPERFAMILY SSF52343 242 382 1.7E-22 T 06-07-2017 CAK77_RS21460 69e98022327c0a4dc0455b57d3e64428 384 SUPERFAMILY SSF46458 5 134 4.04E-19 T 06-07-2017 IPR009050 Globin-like CAK77_RS21460 69e98022327c0a4dc0455b57d3e64428 384 Gene3D G3DSA:1.10.490.10 14 138 1.9E-19 T 06-07-2017 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 CAK77_RS21460 69e98022327c0a4dc0455b57d3e64428 384 Pfam PF00175 Oxidoreductase NAD-binding domain 249 320 8.6E-6 T 06-07-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CAK77_RS15690 38cf88c255755b73478c3bb9fc0fe3b7 212 SUPERFAMILY SSF56959 38 201 8.5E-10 T 06-07-2017 IPR016183 Leukocidin/porin GO:0005576|GO:0051715 CAK77_RS15690 38cf88c255755b73478c3bb9fc0fe3b7 212 Gene3D G3DSA:2.60.40.1650 36 100 2.1E-23 T 06-07-2017 CAK77_RS15690 38cf88c255755b73478c3bb9fc0fe3b7 212 Gene3D G3DSA:2.60.40.1650 149 211 2.1E-23 T 06-07-2017 CAK77_RS15690 38cf88c255755b73478c3bb9fc0fe3b7 212 Pfam PF09203 MspA 41 210 2.0E-47 T 06-07-2017 IPR015286 Porin family, mycobacterial-type CAK77_RS16790 cec559cc6222524c714476cc599f6c92 164 Gene3D G3DSA:3.30.530.20 9 161 2.6E-37 T 06-07-2017 IPR023393 START-like domain CAK77_RS16790 cec559cc6222524c714476cc599f6c92 164 SUPERFAMILY SSF55961 12 162 1.83E-36 T 06-07-2017 CAK77_RS16790 cec559cc6222524c714476cc599f6c92 164 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 25 160 2.9E-21 T 06-07-2017 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CAK77_RS07750 801bfa2596c26d442f710b130915b310 459 Gene3D G3DSA:1.20.1250.20 45 234 1.2E-8 T 06-07-2017 CAK77_RS07750 801bfa2596c26d442f710b130915b310 459 Gene3D G3DSA:1.20.1250.20 265 442 7.6E-14 T 06-07-2017 CAK77_RS07750 801bfa2596c26d442f710b130915b310 459 SUPERFAMILY SSF103473 28 446 5.36E-33 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK77_RS07750 801bfa2596c26d442f710b130915b310 459 Pfam PF11700 Vacuole effluxer Atg22 like 163 446 2.0E-24 T 06-07-2017 IPR024671 Autophagy-related protein 22-like CAK77_RS05520 bdecacd191fe5d84d48c0f1712b91033 239 Pfam PF00753 Metallo-beta-lactamase superfamily 27 213 2.3E-23 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK77_RS05520 bdecacd191fe5d84d48c0f1712b91033 239 SMART SM00849 25 218 4.1E-25 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK77_RS05520 bdecacd191fe5d84d48c0f1712b91033 239 SUPERFAMILY SSF56281 6 232 1.83E-47 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK77_RS05520 bdecacd191fe5d84d48c0f1712b91033 239 Gene3D G3DSA:3.60.15.10 3 228 4.7E-42 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK77_RS03830 8af76c134b563890fbd832740a905e6d 155 SUPERFAMILY SSF55811 6 149 1.76E-35 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAK77_RS03830 8af76c134b563890fbd832740a905e6d 155 Pfam PF00293 NUDIX domain 19 132 6.2E-20 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 CAK77_RS03830 8af76c134b563890fbd832740a905e6d 155 Gene3D G3DSA:3.90.79.10 4 147 5.4E-36 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAK77_RS03830 8af76c134b563890fbd832740a905e6d 155 ProSitePatterns PS00893 Nudix box signature. 48 69 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CAK77_RS03830 8af76c134b563890fbd832740a905e6d 155 PRINTS PR00502 NUDIX hydrolase family signature 43 57 2.7E-6 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CAK77_RS03830 8af76c134b563890fbd832740a905e6d 155 PRINTS PR00502 NUDIX hydrolase family signature 57 72 2.7E-6 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CAK77_RS16040 b7fa2ba3615ffeb43d25c3d531e97b50 113 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 1 113 30.153 T 06-07-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS16040 b7fa2ba3615ffeb43d25c3d531e97b50 113 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 2 112 4.2E-50 T 06-07-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS16040 b7fa2ba3615ffeb43d25c3d531e97b50 113 PIRSF PIRSF002191 1 113 4.1E-49 T 06-07-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS16040 b7fa2ba3615ffeb43d25c3d531e97b50 113 SUPERFAMILY SSF50104 1 112 2.71E-45 T 06-07-2017 IPR008991 Translation protein SH3-like domain CAK77_RS16040 b7fa2ba3615ffeb43d25c3d531e97b50 113 ProSitePatterns PS01015 Ribosomal protein L19 signature. 85 100 - T 06-07-2017 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS16040 b7fa2ba3615ffeb43d25c3d531e97b50 113 PRINTS PR00061 Ribosomal protein L19 signature 3 32 2.4E-42 T 06-07-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS16040 b7fa2ba3615ffeb43d25c3d531e97b50 113 PRINTS PR00061 Ribosomal protein L19 signature 87 112 2.4E-42 T 06-07-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS16040 b7fa2ba3615ffeb43d25c3d531e97b50 113 PRINTS PR00061 Ribosomal protein L19 signature 33 62 2.4E-42 T 06-07-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS16040 b7fa2ba3615ffeb43d25c3d531e97b50 113 Pfam PF01245 Ribosomal protein L19 4 112 9.2E-50 T 06-07-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS06790 bb862b4c8ca4691dff37180dae443428 232 Gene3D G3DSA:2.30.110.10 5 190 2.6E-50 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS06790 bb862b4c8ca4691dff37180dae443428 232 SUPERFAMILY SSF50475 20 190 1.74E-40 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS06790 bb862b4c8ca4691dff37180dae443428 232 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 31 172 4.5E-35 T 06-07-2017 IPR024747 Pyridoxamine 5'-phosphate oxidase-related CAK77_RS04885 12b9294c6ed3488f33ab713dbd01001e 415 PIRSF PIRSF016578 2 401 6.3E-35 T 06-07-2017 CAK77_RS04885 12b9294c6ed3488f33ab713dbd01001e 415 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 28 120 7.6E-13 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS04885 12b9294c6ed3488f33ab713dbd01001e 415 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 254 390 1.2E-20 T 06-07-2017 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain CAK77_RS04885 12b9294c6ed3488f33ab713dbd01001e 415 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 134 221 4.3E-10 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAK77_RS04885 12b9294c6ed3488f33ab713dbd01001e 415 Gene3D G3DSA:2.40.110.10 134 225 1.1E-19 T 06-07-2017 CAK77_RS04885 12b9294c6ed3488f33ab713dbd01001e 415 Gene3D G3DSA:1.10.540.10 7 115 3.0E-28 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS04885 12b9294c6ed3488f33ab713dbd01001e 415 SUPERFAMILY SSF47203 251 404 9.67E-22 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS04885 12b9294c6ed3488f33ab713dbd01001e 415 Gene3D G3DSA:1.20.140.10 226 412 8.0E-58 T 06-07-2017 CAK77_RS04885 12b9294c6ed3488f33ab713dbd01001e 415 SUPERFAMILY SSF56645 20 233 8.12E-43 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK77_RS20495 4118e7ca3932fb53c8b93b99d5b45ca8 277 TIGRFAM TIGR03425 urea_degr_2: urea carboxylase-associated protein 2 45 268 3.9E-84 T 06-07-2017 IPR017792 Urea carboxylase-associated protein 2 CAK77_RS20495 4118e7ca3932fb53c8b93b99d5b45ca8 277 Pfam PF09347 Domain of unknown function (DUF1989) 48 212 7.7E-41 T 06-07-2017 IPR018959 Domain of unknown function DUF1989 CAK77_RS03165 3f56db1517e0928bc4c2aeb4fba8179d 417 Pfam PF00067 Cytochrome P450 287 376 1.6E-13 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS03165 3f56db1517e0928bc4c2aeb4fba8179d 417 PRINTS PR00359 B-class P450 signature 168 183 7.1E-43 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS03165 3f56db1517e0928bc4c2aeb4fba8179d 417 PRINTS PR00359 B-class P450 signature 329 344 7.1E-43 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS03165 3f56db1517e0928bc4c2aeb4fba8179d 417 PRINTS PR00359 B-class P450 signature 205 227 7.1E-43 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS03165 3f56db1517e0928bc4c2aeb4fba8179d 417 PRINTS PR00359 B-class P450 signature 301 328 7.1E-43 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS03165 3f56db1517e0928bc4c2aeb4fba8179d 417 PRINTS PR00359 B-class P450 signature 360 371 7.1E-43 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS03165 3f56db1517e0928bc4c2aeb4fba8179d 417 PRINTS PR00359 B-class P450 signature 351 360 7.1E-43 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS03165 3f56db1517e0928bc4c2aeb4fba8179d 417 PRINTS PR00359 B-class P450 signature 105 116 7.1E-43 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS03165 3f56db1517e0928bc4c2aeb4fba8179d 417 PRINTS PR00359 B-class P450 signature 151 167 7.1E-43 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS03165 3f56db1517e0928bc4c2aeb4fba8179d 417 PRINTS PR00359 B-class P450 signature 284 295 7.1E-43 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS03165 3f56db1517e0928bc4c2aeb4fba8179d 417 SUPERFAMILY SSF48264 15 410 4.06E-74 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS03165 3f56db1517e0928bc4c2aeb4fba8179d 417 Gene3D G3DSA:1.10.630.10 11 409 1.3E-105 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS19600 612b147c38e461ed676f4e3c960d174f 213 PIRSF PIRSF006324 5 213 5.6E-54 T 06-07-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 CAK77_RS19600 612b147c38e461ed676f4e3c960d174f 213 Pfam PF01810 LysE type translocator 19 210 5.2E-27 T 06-07-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 CAK77_RS06075 bdac80aa23befd6daf4be7f5e4329692 284 SUPERFAMILY SSF51735 4 249 5.75E-51 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS06075 bdac80aa23befd6daf4be7f5e4329692 284 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 5.1E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06075 bdac80aa23befd6daf4be7f5e4329692 284 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 170 5.1E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06075 bdac80aa23befd6daf4be7f5e4329692 284 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 5.1E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06075 bdac80aa23befd6daf4be7f5e4329692 284 Pfam PF00106 short chain dehydrogenase 5 183 4.3E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06075 bdac80aa23befd6daf4be7f5e4329692 284 Gene3D G3DSA:3.40.50.720 4 250 1.7E-53 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS06075 bdac80aa23befd6daf4be7f5e4329692 284 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 8.1E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06075 bdac80aa23befd6daf4be7f5e4329692 284 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 8.1E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06075 bdac80aa23befd6daf4be7f5e4329692 284 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 8.1E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06075 bdac80aa23befd6daf4be7f5e4329692 284 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 8.1E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS06075 bdac80aa23befd6daf4be7f5e4329692 284 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 8.1E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS01760 5899bf2b75b62dbe8570ee632508296d 277 PRINTS PR00412 Epoxide hydrolase signature 52 67 1.6E-8 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK77_RS01760 5899bf2b75b62dbe8570ee632508296d 277 PRINTS PR00412 Epoxide hydrolase signature 96 109 1.6E-8 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK77_RS01760 5899bf2b75b62dbe8570ee632508296d 277 PRINTS PR00412 Epoxide hydrolase signature 247 269 1.6E-8 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK77_RS01760 5899bf2b75b62dbe8570ee632508296d 277 Pfam PF00561 alpha/beta hydrolase fold 27 259 2.0E-31 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS01760 5899bf2b75b62dbe8570ee632508296d 277 Gene3D G3DSA:3.40.50.1820 18 273 7.3E-59 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS01760 5899bf2b75b62dbe8570ee632508296d 277 SUPERFAMILY SSF53474 18 271 6.4E-61 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS01760 5899bf2b75b62dbe8570ee632508296d 277 PRINTS PR00111 Alpha/beta hydrolase fold signature 216 230 2.7E-12 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS01760 5899bf2b75b62dbe8570ee632508296d 277 PRINTS PR00111 Alpha/beta hydrolase fold signature 52 67 2.7E-12 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS01760 5899bf2b75b62dbe8570ee632508296d 277 PRINTS PR00111 Alpha/beta hydrolase fold signature 110 123 2.7E-12 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS01760 5899bf2b75b62dbe8570ee632508296d 277 PRINTS PR00111 Alpha/beta hydrolase fold signature 96 109 2.7E-12 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS05225 8105da60a8d56dedcd7aafa9b1649844 249 Gene3D G3DSA:3.40.1010.10 1 141 1.1E-36 T 06-07-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAK77_RS05225 8105da60a8d56dedcd7aafa9b1649844 249 TIGRFAM TIGR02434 CobF: precorrin-6A synthase (deacetylating) 2 245 2.7E-106 T 06-07-2017 IPR012797 Cobalamin (vitamin B12) biosynthesis CobF, precorrin-6A synthase GO:0009236|GO:0043819 KEGG: 00860+2.1.1.152|MetaCyc: PWY-7376 CAK77_RS05225 8105da60a8d56dedcd7aafa9b1649844 249 SUPERFAMILY SSF53790 1 245 2.09E-36 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAK77_RS05225 8105da60a8d56dedcd7aafa9b1649844 249 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 4 220 3.5E-30 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAK77_RS05225 8105da60a8d56dedcd7aafa9b1649844 249 Gene3D G3DSA:3.30.950.10 142 246 3.3E-45 T 06-07-2017 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAK77_RS05225 8105da60a8d56dedcd7aafa9b1649844 249 PIRSF PIRSF036525 1 249 1.3E-105 T 06-07-2017 IPR012797 Cobalamin (vitamin B12) biosynthesis CobF, precorrin-6A synthase GO:0009236|GO:0043819 KEGG: 00860+2.1.1.152|MetaCyc: PWY-7376 CAK77_RS17700 ce46841f57215562544fb62ac5a87fc3 203 SMART SM00855 7 154 6.0E-20 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 CAK77_RS17700 ce46841f57215562544fb62ac5a87fc3 203 Gene3D G3DSA:3.40.50.1240 7 192 1.3E-47 T 06-07-2017 IPR029033 Histidine phosphatase superfamily CAK77_RS17700 ce46841f57215562544fb62ac5a87fc3 203 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 9 192 2.1E-48 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 CAK77_RS17700 ce46841f57215562544fb62ac5a87fc3 203 PIRSF PIRSF000709 5 177 4.7E-11 T 06-07-2017 CAK77_RS17700 ce46841f57215562544fb62ac5a87fc3 203 SUPERFAMILY SSF53254 7 198 6.65E-51 T 06-07-2017 IPR029033 Histidine phosphatase superfamily CAK77_RS00805 aa77f6a6851a53f77a63f4c43a5faeec 313 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 72 217 8.7E-41 T 06-07-2017 IPR004474 Cell envelope-related transcriptional attenuator domain CAK77_RS00805 aa77f6a6851a53f77a63f4c43a5faeec 313 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 71 217 1.1E-39 T 06-07-2017 IPR004474 Cell envelope-related transcriptional attenuator domain CAK77_RS15730 67a1c8d0f8def4d1f9db98c205da4aba 208 Gene3D G3DSA:3.40.50.1820 23 134 1.3E-11 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS15730 67a1c8d0f8def4d1f9db98c205da4aba 208 SUPERFAMILY SSF53474 22 134 4.06E-12 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS21995 4b07400f0723404774690e7254d9e501 251 SUPERFAMILY SSF51621 3 250 1.44E-58 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAK77_RS21995 4b07400f0723404774690e7254d9e501 251 Pfam PF13714 Phosphoenolpyruvate phosphomutase 12 245 5.7E-61 T 06-07-2017 CAK77_RS21995 4b07400f0723404774690e7254d9e501 251 Gene3D G3DSA:3.20.20.60 6 232 2.5E-61 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAK77_RS00945 06abd79ad89cb5d1529c2fccb9e9c599 517 Gene3D G3DSA:3.60.15.10 1 194 9.6E-15 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK77_RS00945 06abd79ad89cb5d1529c2fccb9e9c599 517 Pfam PF00355 Rieske [2Fe-2S] domain 466 506 3.1E-7 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK77_RS00945 06abd79ad89cb5d1529c2fccb9e9c599 517 Gene3D G3DSA:2.102.10.10 465 513 1.9E-11 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK77_RS00945 06abd79ad89cb5d1529c2fccb9e9c599 517 SUPERFAMILY SSF56281 108 236 3.31E-14 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK77_RS00945 06abd79ad89cb5d1529c2fccb9e9c599 517 SUPERFAMILY SSF56281 1 75 3.31E-14 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK77_RS00945 06abd79ad89cb5d1529c2fccb9e9c599 517 Pfam PF13483 Beta-lactamase superfamily domain 2 74 6.2E-7 T 06-07-2017 CAK77_RS00945 06abd79ad89cb5d1529c2fccb9e9c599 517 SUPERFAMILY SSF50022 466 510 7.73E-11 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK77_RS11025 bfacd36c0f90b42465da994277a19801 547 Pfam PF13515 Fusaric acid resistance protein-like 308 433 7.2E-21 T 06-07-2017 CAK77_RS21890 0fdd01fc406060f3cfd96ff771dab892 155 Pfam PF14232 Domain of unknown function (DUF4334) 95 153 5.7E-27 T 06-07-2017 IPR025568 Domain of unknown function DUF4334 CAK77_RS21890 0fdd01fc406060f3cfd96ff771dab892 155 Pfam PF14231 GXWXG protein 26 84 1.5E-24 T 06-07-2017 IPR025951 GXWXG domain CAK77_RS20090 8dc4cf356f9532591c1f1c29925d4079 279 Pfam PF13622 Thioesterase-like superfamily 25 276 1.7E-41 T 06-07-2017 CAK77_RS20090 8dc4cf356f9532591c1f1c29925d4079 279 SUPERFAMILY SSF54637 5 121 1.84E-8 T 06-07-2017 IPR029069 HotDog domain CAK77_RS20090 8dc4cf356f9532591c1f1c29925d4079 279 SUPERFAMILY SSF54637 157 276 3.42E-8 T 06-07-2017 IPR029069 HotDog domain CAK77_RS02600 61d8dc4ae78aa883a68e60e3f11d6fb1 248 Pfam PF02517 CAAX protease self-immunity 122 235 7.9E-12 T 06-07-2017 IPR003675 CAAX amino terminal protease GO:0016020 CAK77_RS02600 61d8dc4ae78aa883a68e60e3f11d6fb1 248 PIRSF PIRSF026622 12 248 7.5E-91 T 06-07-2017 IPR015837 Uncharacterised conserved protein UCP026622, CAAX protease-type CAK77_RS04900 a537b7de42e1456d10d9d4071bd5f621 186 Pfam PF00440 Bacterial regulatory proteins, tetR family 8 51 1.1E-15 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS04900 a537b7de42e1456d10d9d4071bd5f621 186 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 8 21 5.7E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS04900 a537b7de42e1456d10d9d4071bd5f621 186 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 52 5.7E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS04900 a537b7de42e1456d10d9d4071bd5f621 186 SUPERFAMILY SSF46689 4 65 2.43E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS04900 a537b7de42e1456d10d9d4071bd5f621 186 Gene3D G3DSA:1.10.357.10 4 181 5.3E-30 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS13015 9a3d45e6f4eaa63566224d0c0bf6dfa1 272 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 5 260 34.377 T 06-07-2017 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 CAK77_RS13015 9a3d45e6f4eaa63566224d0c0bf6dfa1 272 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 54 72 - T 06-07-2017 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 CAK77_RS13015 9a3d45e6f4eaa63566224d0c0bf6dfa1 272 SUPERFAMILY SSF51366 15 260 1.57E-78 T 06-07-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CAK77_RS13015 9a3d45e6f4eaa63566224d0c0bf6dfa1 272 Pfam PF00218 Indole-3-glycerol phosphate synthase 7 258 3.5E-80 T 06-07-2017 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 CAK77_RS13015 9a3d45e6f4eaa63566224d0c0bf6dfa1 272 Gene3D G3DSA:3.20.20.70 5 262 1.8E-93 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK77_RS13015 9a3d45e6f4eaa63566224d0c0bf6dfa1 272 Hamap MF_00134_A Indole-3-glycerol phosphate synthase [trpC]. 36 256 29.459 T 06-07-2017 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 CAK77_RS21550 815da9349216132101b58473a3841c28 627 SUPERFAMILY SSF52540 29 298 1.12E-26 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS21550 815da9349216132101b58473a3841c28 627 Pfam PF00350 Dynamin family 52 209 1.9E-13 T 06-07-2017 IPR022812 Dynamin superfamily CAK77_RS21550 815da9349216132101b58473a3841c28 627 Gene3D G3DSA:3.40.50.300 43 84 2.2E-16 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS21550 815da9349216132101b58473a3841c28 627 Gene3D G3DSA:3.40.50.300 141 252 2.2E-16 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS03630 da8c26035676b29d2bac705d51477155 422 Gene3D G3DSA:2.30.250.10 84 208 7.4E-31 T 06-07-2017 IPR023358 Peptidase M18, domain 2 GO:0004177 CAK77_RS03630 da8c26035676b29d2bac705d51477155 422 Gene3D G3DSA:3.40.630.10 212 417 1.0E-100 T 06-07-2017 CAK77_RS03630 da8c26035676b29d2bac705d51477155 422 Gene3D G3DSA:3.40.630.10 4 83 1.0E-100 T 06-07-2017 CAK77_RS03630 da8c26035676b29d2bac705d51477155 422 Pfam PF02127 Aminopeptidase I zinc metalloprotease (M18) 11 415 1.7E-131 T 06-07-2017 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 CAK77_RS03630 da8c26035676b29d2bac705d51477155 422 SUPERFAMILY SSF53187 6 84 2.15E-93 T 06-07-2017 CAK77_RS03630 da8c26035676b29d2bac705d51477155 422 SUPERFAMILY SSF53187 203 417 2.15E-93 T 06-07-2017 CAK77_RS03630 da8c26035676b29d2bac705d51477155 422 SUPERFAMILY SSF101821 85 202 5.4E-25 T 06-07-2017 CAK77_RS03630 da8c26035676b29d2bac705d51477155 422 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 294 310 3.6E-47 T 06-07-2017 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 CAK77_RS03630 da8c26035676b29d2bac705d51477155 422 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 141 158 3.6E-47 T 06-07-2017 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 CAK77_RS03630 da8c26035676b29d2bac705d51477155 422 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 251 269 3.6E-47 T 06-07-2017 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 CAK77_RS03630 da8c26035676b29d2bac705d51477155 422 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 383 398 3.6E-47 T 06-07-2017 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 CAK77_RS03630 da8c26035676b29d2bac705d51477155 422 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 73 89 3.6E-47 T 06-07-2017 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 CAK77_RS03630 da8c26035676b29d2bac705d51477155 422 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 106 126 3.6E-47 T 06-07-2017 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 CAK77_RS13200 9d61710685a0e1236542e884764c179b 145 Pfam PF04075 Domain of unknown function (DUF385) 16 143 9.4E-47 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CAK77_RS13200 9d61710685a0e1236542e884764c179b 145 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 32 142 2.4E-34 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CAK77_RS19690 9a7b921a2b55fe6318b15fa4529310f4 380 Gene3D G3DSA:3.40.50.2000 177 347 9.2E-21 T 06-07-2017 CAK77_RS19690 9a7b921a2b55fe6318b15fa4529310f4 380 SUPERFAMILY SSF53756 2 366 1.88E-69 T 06-07-2017 CAK77_RS19690 9a7b921a2b55fe6318b15fa4529310f4 380 Pfam PF00534 Glycosyl transferases group 1 195 346 4.4E-22 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 CAK77_RS19690 9a7b921a2b55fe6318b15fa4529310f4 380 Pfam PF13439 Glycosyltransferase Family 4 14 184 2.9E-25 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 CAK77_RS19690 9a7b921a2b55fe6318b15fa4529310f4 380 Gene3D G3DSA:3.40.50.2000 20 162 9.5E-9 T 06-07-2017 CAK77_RS04645 7c5a599c766376dd98dfd3d621ad5dcd 470 SUPERFAMILY SSF103473 252 441 2.44E-67 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK77_RS04645 7c5a599c766376dd98dfd3d621ad5dcd 470 SUPERFAMILY SSF103473 12 206 2.44E-67 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK77_RS04645 7c5a599c766376dd98dfd3d621ad5dcd 470 Pfam PF07690 Major Facilitator Superfamily 21 412 2.7E-60 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK77_RS04645 7c5a599c766376dd98dfd3d621ad5dcd 470 PRINTS PR01036 Tetracycline resistance protein TetB signature 79 101 5.4E-10 T 06-07-2017 CAK77_RS04645 7c5a599c766376dd98dfd3d621ad5dcd 470 PRINTS PR01036 Tetracycline resistance protein TetB signature 341 361 5.4E-10 T 06-07-2017 CAK77_RS04645 7c5a599c766376dd98dfd3d621ad5dcd 470 PRINTS PR01036 Tetracycline resistance protein TetB signature 305 329 5.4E-10 T 06-07-2017 CAK77_RS04645 7c5a599c766376dd98dfd3d621ad5dcd 470 PRINTS PR01036 Tetracycline resistance protein TetB signature 141 165 5.4E-10 T 06-07-2017 CAK77_RS04645 7c5a599c766376dd98dfd3d621ad5dcd 470 PRINTS PR01036 Tetracycline resistance protein TetB signature 19 43 5.4E-10 T 06-07-2017 CAK77_RS04645 7c5a599c766376dd98dfd3d621ad5dcd 470 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 15 419 1.2E-82 T 06-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CAK77_RS04645 7c5a599c766376dd98dfd3d621ad5dcd 470 Gene3D G3DSA:1.20.1250.20 11 199 1.4E-36 T 06-07-2017 CAK77_RS04645 7c5a599c766376dd98dfd3d621ad5dcd 470 Gene3D G3DSA:1.20.1250.20 273 441 5.4E-19 T 06-07-2017 CAK77_RS16530 d9adf197d089111d508783bc0bfd10fc 409 Pfam PF16653 Saccharopine dehydrogenase C-terminal domain 144 396 1.8E-17 T 06-07-2017 IPR032095 Saccharopine dehydrogenase, C-terminal Reactome: R-HSA-71064 CAK77_RS16530 d9adf197d089111d508783bc0bfd10fc 409 Gene3D G3DSA:3.40.50.720 1 168 9.3E-17 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS16530 d9adf197d089111d508783bc0bfd10fc 409 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 3 139 8.8E-17 T 06-07-2017 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 CAK77_RS16530 d9adf197d089111d508783bc0bfd10fc 409 SUPERFAMILY SSF51735 1 170 2.71E-13 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS15550 e9415d6108bd0d4beae830dab0f56e46 444 Pfam PF01554 MatE 23 183 3.4E-26 T 06-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CAK77_RS15550 e9415d6108bd0d4beae830dab0f56e46 444 Pfam PF01554 MatE 244 399 3.1E-18 T 06-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CAK77_RS15550 e9415d6108bd0d4beae830dab0f56e46 444 TIGRFAM TIGR00797 matE: MATE efflux family protein 23 414 2.6E-96 T 06-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CAK77_RS03345 e22a2ba309bb75500cc1f5afca84289e 564 SUPERFAMILY SSF52540 9 168 5.64E-28 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS03345 e22a2ba309bb75500cc1f5afca84289e 564 SMART SM00487 8 186 5.4E-15 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain CAK77_RS03345 e22a2ba309bb75500cc1f5afca84289e 564 Pfam PF04851 Type III restriction enzyme, res subunit 11 164 2.7E-17 T 06-07-2017 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CAK77_RS03345 e22a2ba309bb75500cc1f5afca84289e 564 Gene3D G3DSA:3.40.50.300 7 168 2.6E-21 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS03345 e22a2ba309bb75500cc1f5afca84289e 564 Gene3D G3DSA:3.40.50.300 276 380 8.5E-7 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS03345 e22a2ba309bb75500cc1f5afca84289e 564 SUPERFAMILY SSF52540 254 378 2.9E-16 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS03345 e22a2ba309bb75500cc1f5afca84289e 564 SUPERFAMILY SSF52540 125 196 2.9E-16 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS06815 77ec8bb94aa62fd3aaaf066efaa5ef3f 215 Pfam PF01596 O-methyltransferase 40 213 3.6E-19 T 06-07-2017 IPR002935 O-methyltransferase, family 3 GO:0008171 CAK77_RS06815 77ec8bb94aa62fd3aaaf066efaa5ef3f 215 Gene3D G3DSA:3.40.50.150 21 214 1.2E-47 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS06815 77ec8bb94aa62fd3aaaf066efaa5ef3f 215 SUPERFAMILY SSF53335 36 214 3.7E-29 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS07905 c0f3659c8576a379f43abf18591790d5 183 Pfam PF14279 HNH endonuclease 99 145 3.9E-13 T 06-07-2017 IPR029471 HNH endonuclease 5 CAK77_RS07905 c0f3659c8576a379f43abf18591790d5 183 SMART SM00507 86 135 2.6E-16 T 06-07-2017 IPR003615 HNH nuclease CAK77_RS18190 9547a46abd75dddf546d7a2c83cc61db 140 Gene3D G3DSA:3.10.180.10 18 138 2.3E-23 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK77_RS18190 9547a46abd75dddf546d7a2c83cc61db 140 SUPERFAMILY SSF54593 13 136 1.65E-21 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK77_RS17270 7db241e0d00fe8edb1a7c3b6ce82bea7 151 Pfam PF01740 STAS domain 29 98 2.0E-7 T 06-07-2017 IPR002645 STAS domain CAK77_RS17270 7db241e0d00fe8edb1a7c3b6ce82bea7 151 Gene3D G3DSA:3.30.750.24 28 110 7.5E-11 T 06-07-2017 IPR002645 STAS domain CAK77_RS17270 7db241e0d00fe8edb1a7c3b6ce82bea7 151 SUPERFAMILY SSF52091 26 128 8.63E-11 T 06-07-2017 IPR002645 STAS domain CAK77_RS02490 5c851dd24a9eccce5844c7444abdaac2 68 Pfam PF14029 Protein of unknown function (DUF4244) 13 65 2.7E-24 T 06-07-2017 IPR025338 Protein of unknown function DUF4244 CAK77_RS16890 c66fc2c25e317b99c2c07e3ab76db7b2 289 SUPERFAMILY SSF103481 200 276 5.23E-5 T 06-07-2017 CAK77_RS16890 c66fc2c25e317b99c2c07e3ab76db7b2 289 Pfam PF00892 EamA-like transporter family 144 276 3.3E-14 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAK77_RS16890 c66fc2c25e317b99c2c07e3ab76db7b2 289 SUPERFAMILY SSF103481 45 133 2.35E-7 T 06-07-2017 CAK77_RS07260 041ae21c18e9b6c8022fb7ef67d79b27 257 Gene3D G3DSA:1.20.120.220 93 251 4.4E-42 T 06-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 CAK77_RS07260 041ae21c18e9b6c8022fb7ef67d79b27 257 ProSitePatterns PS00449 ATP synthase a subunit signature. 189 198 - T 06-07-2017 IPR023011 ATPase, F0 complex, subunit A, active site Reactome: R-HSA-163210 CAK77_RS07260 041ae21c18e9b6c8022fb7ef67d79b27 257 SUPERFAMILY SSF81336 92 247 2.09E-35 T 06-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 CAK77_RS07260 041ae21c18e9b6c8022fb7ef67d79b27 257 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 40 249 4.0E-37 T 06-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 CAK77_RS07260 041ae21c18e9b6c8022fb7ef67d79b27 257 PRINTS PR00123 ATP synthase A subunit signature 233 248 1.1E-16 T 06-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 CAK77_RS07260 041ae21c18e9b6c8022fb7ef67d79b27 257 PRINTS PR00123 ATP synthase A subunit signature 97 113 1.1E-16 T 06-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 CAK77_RS07260 041ae21c18e9b6c8022fb7ef67d79b27 257 PRINTS PR00123 ATP synthase A subunit signature 186 208 1.1E-16 T 06-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 CAK77_RS07260 041ae21c18e9b6c8022fb7ef67d79b27 257 Hamap MF_01393 ATP synthase subunit a [atpB]. 11 253 13.438 T 06-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 CAK77_RS07260 041ae21c18e9b6c8022fb7ef67d79b27 257 Pfam PF00119 ATP synthase A chain 38 247 4.5E-49 T 06-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 CAK77_RS19360 913ee796571938a0471f57265b34ef76 310 SUPERFAMILY SSF53474 7 301 5.62E-56 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS19360 913ee796571938a0471f57265b34ef76 310 Pfam PF00561 alpha/beta hydrolase fold 33 150 1.4E-17 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS19360 913ee796571938a0471f57265b34ef76 310 Gene3D G3DSA:3.40.50.1820 13 302 2.4E-59 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS00385 5562e537f2cb6fd35d59cea40f2da0de 145 Pfam PF03994 Domain of Unknown Function (DUF350) 20 73 1.9E-13 T 06-07-2017 IPR007140 Protein of unknown function DUF350 CAK77_RS00385 5562e537f2cb6fd35d59cea40f2da0de 145 Pfam PF03994 Domain of Unknown Function (DUF350) 90 144 1.3E-9 T 06-07-2017 IPR007140 Protein of unknown function DUF350 CAK77_RS05240 2baf39cab23f293658f8f481980847ab 302 PIRSF PIRSF028756 14 297 4.2E-120 T 06-07-2017 IPR016898 Polyphosphate kinase 2 CAK77_RS05240 2baf39cab23f293658f8f481980847ab 302 Gene3D G3DSA:3.40.50.300 32 289 1.5E-107 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS05240 2baf39cab23f293658f8f481980847ab 302 SUPERFAMILY SSF52540 80 267 6.42E-28 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS05240 2baf39cab23f293658f8f481980847ab 302 TIGRFAM TIGR03707 PPK2_P_aer: polyphosphate kinase 2 48 275 4.9E-114 T 06-07-2017 IPR022486 Polyphosphate kinase 2, PA0141 GO:0006793|GO:0008976 CAK77_RS05240 2baf39cab23f293658f8f481980847ab 302 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 48 274 4.5E-104 T 06-07-2017 IPR022488 Polyphosphate kinase-2-related CAK77_RS18205 216ad59820c0afda7a130c72288c5c10 593 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 349 355 5.8E-34 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 CAK77_RS18205 216ad59820c0afda7a130c72288c5c10 593 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 64 76 5.8E-34 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 CAK77_RS18205 216ad59820c0afda7a130c72288c5c10 593 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 35 47 5.8E-34 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 CAK77_RS18205 216ad59820c0afda7a130c72288c5c10 593 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 110 122 5.8E-34 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 CAK77_RS18205 216ad59820c0afda7a130c72288c5c10 593 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 379 391 5.8E-34 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 CAK77_RS18205 216ad59820c0afda7a130c72288c5c10 593 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 48 58 5.8E-34 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 CAK77_RS18205 216ad59820c0afda7a130c72288c5c10 593 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 413 536 5.3E-28 T 06-07-2017 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 CAK77_RS18205 216ad59820c0afda7a130c72288c5c10 593 ProSitePatterns PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1. 40 57 - T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 CAK77_RS18205 216ad59820c0afda7a130c72288c5c10 593 ProSitePatterns PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2. 384 394 - T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 CAK77_RS18205 216ad59820c0afda7a130c72288c5c10 593 Gene3D G3DSA:3.50.50.60 33 269 3.2E-45 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS18205 216ad59820c0afda7a130c72288c5c10 593 SUPERFAMILY SSF51905 298 360 1.19E-37 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS18205 216ad59820c0afda7a130c72288c5c10 593 SUPERFAMILY SSF51905 34 261 1.19E-37 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS18205 216ad59820c0afda7a130c72288c5c10 593 Pfam PF01266 FAD dependent oxidoreductase 36 385 6.0E-47 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CAK77_RS05735 0f154b67561bab01a6e1dbacfe2b1028 1216 SMART SM00487 645 835 6.5E-27 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain CAK77_RS05735 0f154b67561bab01a6e1dbacfe2b1028 1216 SMART SM00490 871 955 8.5E-17 T 06-07-2017 IPR001650 Helicase, C-terminal CAK77_RS05735 0f154b67561bab01a6e1dbacfe2b1028 1216 Gene3D G3DSA:3.40.50.300 634 829 3.6E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS05735 0f154b67561bab01a6e1dbacfe2b1028 1216 Pfam PF03461 TRCF domain 1056 1138 1.6E-22 T 06-07-2017 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 CAK77_RS05735 0f154b67561bab01a6e1dbacfe2b1028 1216 SUPERFAMILY SSF52540 570 828 5.84E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS05735 0f154b67561bab01a6e1dbacfe2b1028 1216 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 167 1128 0.0 T 06-07-2017 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 CAK77_RS05735 0f154b67561bab01a6e1dbacfe2b1028 1216 Pfam PF00270 DEAD/DEAH box helicase 670 811 1.2E-14 T 06-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CAK77_RS05735 0f154b67561bab01a6e1dbacfe2b1028 1216 Gene3D G3DSA:3.40.50.300 830 1008 1.7E-32 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS05735 0f154b67561bab01a6e1dbacfe2b1028 1216 SUPERFAMILY SSF143517 1045 1164 3.4E-31 T 06-07-2017 CAK77_RS05735 0f154b67561bab01a6e1dbacfe2b1028 1216 SUPERFAMILY SSF141259 510 587 1.57E-16 T 06-07-2017 IPR003711 CarD-like/TRCF domain CAK77_RS05735 0f154b67561bab01a6e1dbacfe2b1028 1216 SUPERFAMILY SSF52540 827 1035 5.09E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS05735 0f154b67561bab01a6e1dbacfe2b1028 1216 SMART SM00982 1055 1153 5.9E-36 T 06-07-2017 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 CAK77_RS05735 0f154b67561bab01a6e1dbacfe2b1028 1216 SUPERFAMILY SSF52540 37 387 3.67E-72 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS05735 0f154b67561bab01a6e1dbacfe2b1028 1216 SMART SM01058 516 621 4.7E-44 T 06-07-2017 IPR003711 CarD-like/TRCF domain CAK77_RS05735 0f154b67561bab01a6e1dbacfe2b1028 1216 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 47 1149 27.999 T 06-07-2017 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 CAK77_RS05735 0f154b67561bab01a6e1dbacfe2b1028 1216 Pfam PF00271 Helicase conserved C-terminal domain 854 954 7.8E-15 T 06-07-2017 IPR001650 Helicase, C-terminal CAK77_RS05735 0f154b67561bab01a6e1dbacfe2b1028 1216 Gene3D G3DSA:3.30.2060.10 150 229 1.9E-16 T 06-07-2017 CAK77_RS05735 0f154b67561bab01a6e1dbacfe2b1028 1216 Pfam PF02559 CarD-like/TRCF domain 517 620 1.6E-27 T 06-07-2017 IPR003711 CarD-like/TRCF domain CAK77_RS05735 0f154b67561bab01a6e1dbacfe2b1028 1216 SUPERFAMILY SSF52540 407 498 7.43E-7 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS23705 754e3d46b0a1f9bc3515899f821276b7 281 Pfam PF01734 Patatin-like phospholipase 6 173 1.7E-21 T 06-07-2017 IPR002641 Patatin/Phospholipase A2-related GO:0006629 CAK77_RS23705 754e3d46b0a1f9bc3515899f821276b7 281 Gene3D G3DSA:3.40.1090.10 10 176 3.4E-13 T 06-07-2017 CAK77_RS23705 754e3d46b0a1f9bc3515899f821276b7 281 SUPERFAMILY SSF52151 2 190 1.49E-50 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAK77_RS17140 85ee819bffc090e54c2ffbaf830a9486 248 Gene3D G3DSA:3.40.50.1220 6 31 3.4E-42 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAK77_RS17140 85ee819bffc090e54c2ffbaf830a9486 248 Gene3D G3DSA:3.40.50.1220 80 120 3.4E-42 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAK77_RS17140 85ee819bffc090e54c2ffbaf830a9486 248 Gene3D G3DSA:3.40.50.1220 176 242 3.4E-42 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAK77_RS17140 85ee819bffc090e54c2ffbaf830a9486 248 SUPERFAMILY SSF52467 6 245 3.07E-81 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAK77_RS17140 85ee819bffc090e54c2ffbaf830a9486 248 Gene3D G3DSA:3.30.1600.10 121 167 5.7E-26 T 06-07-2017 IPR026591 Sirtuin family, catalytic core small domain CAK77_RS17140 85ee819bffc090e54c2ffbaf830a9486 248 Gene3D G3DSA:3.30.1600.10 32 72 5.7E-26 T 06-07-2017 IPR026591 Sirtuin family, catalytic core small domain CAK77_RS17140 85ee819bffc090e54c2ffbaf830a9486 248 Hamap MF_01121 NAD-dependent protein deacylase [cobB]. 16 247 54.057 T 06-07-2017 IPR027546 Sirtuin, class III GO:0036054|GO:0036055|GO:0070403 CAK77_RS17140 85ee819bffc090e54c2ffbaf830a9486 248 Pfam PF02146 Sir2 family 23 197 1.9E-50 T 06-07-2017 IPR003000 Sirtuin family GO:0070403 CAK77_RS15650 75da00cb9e22d71c3b2c7db86cb1ebb1 471 SUPERFAMILY SSF52777 42 213 4.82E-19 T 06-07-2017 CAK77_RS15650 75da00cb9e22d71c3b2c7db86cb1ebb1 471 SUPERFAMILY SSF52777 236 466 1.33E-17 T 06-07-2017 CAK77_RS15650 75da00cb9e22d71c3b2c7db86cb1ebb1 471 Pfam PF00668 Condensation domain 71 336 4.3E-9 T 06-07-2017 IPR001242 Condensation domain CAK77_RS17205 42ab79c890b7c38ce77f022a3b656d67 501 Pfam PF00135 Carboxylesterase family 8 481 9.0E-96 T 06-07-2017 IPR002018 Carboxylesterase, type B CAK77_RS17205 42ab79c890b7c38ce77f022a3b656d67 501 ProSitePatterns PS01173 Lipolytic enzymes "G-D-X-G" family, putative histidine active site. 103 118 - T 06-07-2017 IPR002168 Lipase, GDXG, putative histidine active site GO:0008152|GO:0016787 Reactome: R-HSA-163560 CAK77_RS17205 42ab79c890b7c38ce77f022a3b656d67 501 SUPERFAMILY SSF53474 6 496 2.44E-114 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS17205 42ab79c890b7c38ce77f022a3b656d67 501 Gene3D G3DSA:3.40.50.1820 4 497 1.3E-127 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS17205 42ab79c890b7c38ce77f022a3b656d67 501 ProSitePatterns PS00941 Carboxylesterases type-B signature 2. 82 92 - T 06-07-2017 IPR019819 Carboxylesterase type B, conserved site CAK77_RS17205 42ab79c890b7c38ce77f022a3b656d67 501 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 181 196 - T 06-07-2017 IPR019826 Carboxylesterase type B, active site CAK77_RS18310 a556e1b7704b8322da9a472f5318cbcb 260 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 27 136 1.3E-30 T 06-07-2017 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK77_RS18310 a556e1b7704b8322da9a472f5318cbcb 260 SUPERFAMILY SSF46548 132 257 7.85E-33 T 06-07-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 CAK77_RS18310 a556e1b7704b8322da9a472f5318cbcb 260 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 29 253 4.7E-71 T 06-07-2017 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK77_RS18310 a556e1b7704b8322da9a472f5318cbcb 260 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 173 184 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CAK77_RS18310 a556e1b7704b8322da9a472f5318cbcb 260 SUPERFAMILY SSF54292 24 131 3.46E-24 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK77_RS18310 a556e1b7704b8322da9a472f5318cbcb 260 Gene3D G3DSA:3.10.20.30 21 131 3.9E-34 T 06-07-2017 IPR012675 Beta-grasp domain CAK77_RS18310 a556e1b7704b8322da9a472f5318cbcb 260 Pfam PF13183 4Fe-4S dicluster domain 171 243 9.6E-11 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CAK77_RS18310 a556e1b7704b8322da9a472f5318cbcb 260 Gene3D G3DSA:1.10.1060.10 132 257 5.7E-40 T 06-07-2017 CAK77_RS24160 e47ec08420e51581528ad3df3f7249e1 220 SUPERFAMILY SSF48498 95 203 3.88E-12 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS24160 e47ec08420e51581528ad3df3f7249e1 220 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 71 5.1E-15 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS24160 e47ec08420e51581528ad3df3f7249e1 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 40 5.8E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS24160 e47ec08420e51581528ad3df3f7249e1 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 48 71 5.8E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS24160 e47ec08420e51581528ad3df3f7249e1 220 Gene3D G3DSA:1.10.357.10 74 205 2.3E-35 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS24160 e47ec08420e51581528ad3df3f7249e1 220 SUPERFAMILY SSF46689 18 91 2.0E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS24160 e47ec08420e51581528ad3df3f7249e1 220 Gene3D G3DSA:1.10.10.60 18 73 3.0E-22 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS07640 20302cbd64d1b7d7bee617ac99fd0017 276 Gene3D G3DSA:3.40.50.150 18 245 2.3E-21 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS07640 20302cbd64d1b7d7bee617ac99fd0017 276 Pfam PF04072 Leucine carboxyl methyltransferase 59 175 3.0E-10 T 06-07-2017 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 CAK77_RS07640 20302cbd64d1b7d7bee617ac99fd0017 276 SUPERFAMILY SSF53335 13 246 2.49E-41 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS07640 20302cbd64d1b7d7bee617ac99fd0017 276 PIRSF PIRSF028177 3 276 1.7E-48 T 06-07-2017 IPR016874 Tetracenomycin polyketide synthesis O-methyltransferase TcmP GO:0017000|GO:1901106 CAK77_RS10440 c55e7c6ee1b217a3c483e1edc1d8dc89 538 Pfam PF00361 Proton-conducting membrane transporter 168 474 4.3E-71 T 06-07-2017 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS10440 c55e7c6ee1b217a3c483e1edc1d8dc89 538 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 12 527 17.444 T 06-07-2017 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 CAK77_RS10440 c55e7c6ee1b217a3c483e1edc1d8dc89 538 TIGRFAM TIGR01770 NDH_I_N: proton-translocating NADH-quinone oxidoreductase, chain N 140 526 1.0E-116 T 06-07-2017 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 CAK77_RS09325 2c73f99dd5c443ea31cb64a68aff699e 149 Gene3D G3DSA:1.10.10.10 10 146 4.8E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS09325 2c73f99dd5c443ea31cb64a68aff699e 149 SMART SM00347 31 131 3.3E-17 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK77_RS09325 2c73f99dd5c443ea31cb64a68aff699e 149 SUPERFAMILY SSF46785 9 146 1.78E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS09325 2c73f99dd5c443ea31cb64a68aff699e 149 Pfam PF01047 MarR family 39 87 1.3E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK77_RS01090 361a25c4bd94ee93ee6f4844b6b615c9 1071 Pfam PF14896 EmbC C-terminal domain 697 1068 2.5E-146 T 06-07-2017 IPR032731 Arabinosyltransferase, C-terminal CAK77_RS01090 361a25c4bd94ee93ee6f4844b6b615c9 1071 Gene3D G3DSA:2.60.120.610 38 217 6.4E-63 T 06-07-2017 IPR027451 Arabinofuranosyltransferase, domain 1 CAK77_RS01090 361a25c4bd94ee93ee6f4844b6b615c9 1071 Pfam PF04602 Mycobacterial cell wall arabinan synthesis protein 18 666 1.2E-277 T 06-07-2017 IPR007680 Arabinofuranosyltransferase, N-terminal GO:0052636|GO:0071766 CAK77_RS22165 b8638056f4e1380eb430f469301adbdd 283 SUPERFAMILY SSF54637 171 281 5.04E-21 T 06-07-2017 IPR029069 HotDog domain CAK77_RS22165 b8638056f4e1380eb430f469301adbdd 283 PRINTS PR01483 Fatty acid synthase signature 178 200 3.0E-7 T 06-07-2017 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 CAK77_RS22165 b8638056f4e1380eb430f469301adbdd 283 PRINTS PR01483 Fatty acid synthase signature 200 221 3.0E-7 T 06-07-2017 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 CAK77_RS22165 b8638056f4e1380eb430f469301adbdd 283 Pfam PF01575 MaoC like domain 173 253 2.2E-19 T 06-07-2017 IPR002539 MaoC-like domain CAK77_RS22165 b8638056f4e1380eb430f469301adbdd 283 Gene3D G3DSA:3.10.129.10 173 281 3.4E-24 T 06-07-2017 IPR029069 HotDog domain CAK77_RS22165 b8638056f4e1380eb430f469301adbdd 283 Gene3D G3DSA:3.10.129.10 58 149 2.7E-5 T 06-07-2017 IPR029069 HotDog domain CAK77_RS22165 b8638056f4e1380eb430f469301adbdd 283 SUPERFAMILY SSF54637 39 162 1.62E-8 T 06-07-2017 IPR029069 HotDog domain CAK77_RS02660 114f11d53da3cc8a34752b48d2f61e63 450 Pfam PF01433 Peptidase family M1 34 355 5.5E-40 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CAK77_RS02660 114f11d53da3cc8a34752b48d2f61e63 450 Gene3D G3DSA:1.10.390.10 314 448 7.1E-22 T 06-07-2017 CAK77_RS02660 114f11d53da3cc8a34752b48d2f61e63 450 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 196 211 8.0E-15 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CAK77_RS02660 114f11d53da3cc8a34752b48d2f61e63 450 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 149 164 8.0E-15 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CAK77_RS02660 114f11d53da3cc8a34752b48d2f61e63 450 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 319 331 8.0E-15 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CAK77_RS02660 114f11d53da3cc8a34752b48d2f61e63 450 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 300 315 8.0E-15 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CAK77_RS02660 114f11d53da3cc8a34752b48d2f61e63 450 SUPERFAMILY SSF55486 227 447 4.98E-51 T 06-07-2017 CAK77_RS02660 114f11d53da3cc8a34752b48d2f61e63 450 SUPERFAMILY SSF63737 19 213 3.79E-35 T 06-07-2017 CAK77_RS11775 3813d5724d61e7b41332a90e816451ea 577 Gene3D G3DSA:3.20.20.140 498 575 5.0E-196 T 06-07-2017 CAK77_RS11775 3813d5724d61e7b41332a90e816451ea 577 Gene3D G3DSA:3.20.20.140 143 439 5.0E-196 T 06-07-2017 CAK77_RS11775 3813d5724d61e7b41332a90e816451ea 577 TIGRFAM TIGR01792 urease_alph: urease, alpha subunit 4 577 9.2E-270 T 06-07-2017 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAK77_RS11775 3813d5724d61e7b41332a90e816451ea 577 SUPERFAMILY SSF51556 491 577 1.19E-185 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK77_RS11775 3813d5724d61e7b41332a90e816451ea 577 SUPERFAMILY SSF51556 136 442 1.19E-185 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK77_RS11775 3813d5724d61e7b41332a90e816451ea 577 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 302 319 5.7E-32 T 06-07-2017 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAK77_RS11775 3813d5724d61e7b41332a90e816451ea 577 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 411 426 5.7E-32 T 06-07-2017 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAK77_RS11775 3813d5724d61e7b41332a90e816451ea 577 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 437 450 5.7E-32 T 06-07-2017 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAK77_RS11775 3813d5724d61e7b41332a90e816451ea 577 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 341 357 5.7E-32 T 06-07-2017 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAK77_RS11775 3813d5724d61e7b41332a90e816451ea 577 Hamap MF_01953 Urease subunit alpha [ureC]. 2 577 55.406 T 06-07-2017 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAK77_RS11775 3813d5724d61e7b41332a90e816451ea 577 Pfam PF00449 Urease alpha-subunit, N-terminal domain 3 126 9.2E-53 T 06-07-2017 IPR011612 Urease alpha-subunit, N-terminal domain KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAK77_RS11775 3813d5724d61e7b41332a90e816451ea 577 Pfam PF01979 Amidohydrolase family 132 460 8.6E-71 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAK77_RS11775 3813d5724d61e7b41332a90e816451ea 577 ProSitePatterns PS00145 Urease active site. 324 340 - T 06-07-2017 IPR017950 Urease active site GO:0009039 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAK77_RS11775 3813d5724d61e7b41332a90e816451ea 577 ProSitePatterns PS01120 Urease nickel ligands signature. 134 147 - T 06-07-2017 IPR029754 Urease nickel binding site GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAK77_RS11775 3813d5724d61e7b41332a90e816451ea 577 Gene3D G3DSA:2.30.40.10 72 142 3.6E-12 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK77_RS11775 3813d5724d61e7b41332a90e816451ea 577 SUPERFAMILY SSF51338 3 182 1.11E-56 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK77_RS09525 9f035b65e6808e874b99066243b8bf71 349 Gene3D G3DSA:2.60.40.420 130 306 1.5E-33 T 06-07-2017 IPR008972 Cupredoxin CAK77_RS09525 9f035b65e6808e874b99066243b8bf71 349 SUPERFAMILY SSF81464 21 121 5.56E-17 T 06-07-2017 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK77_RS09525 9f035b65e6808e874b99066243b8bf71 349 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 234 288 - T 06-07-2017 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK77_RS09525 9f035b65e6808e874b99066243b8bf71 349 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 217 292 2.5E-10 T 06-07-2017 IPR002429 Cytochrome c oxidase subunit II C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK77_RS09525 9f035b65e6808e874b99066243b8bf71 349 Gene3D G3DSA:1.10.287.90 34 122 5.9E-14 T 06-07-2017 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK77_RS09525 9f035b65e6808e874b99066243b8bf71 349 SUPERFAMILY SSF49503 129 309 2.51E-30 T 06-07-2017 IPR008972 Cupredoxin CAK77_RS00875 e557d1ef4ed2509542a8098e0088b3f0 512 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 12 217 1.6E-13 T 06-07-2017 CAK77_RS00875 e557d1ef4ed2509542a8098e0088b3f0 512 Gene3D G3DSA:3.50.50.60 340 454 2.0E-4 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS00875 e557d1ef4ed2509542a8098e0088b3f0 512 SUPERFAMILY SSF51905 8 230 2.05E-50 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS00875 e557d1ef4ed2509542a8098e0088b3f0 512 SUPERFAMILY SSF51905 305 427 2.05E-50 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS00875 e557d1ef4ed2509542a8098e0088b3f0 512 Gene3D G3DSA:3.50.50.60 262 339 1.8E-5 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS00875 e557d1ef4ed2509542a8098e0088b3f0 512 Gene3D G3DSA:3.50.50.60 3 209 1.1E-52 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS00875 e557d1ef4ed2509542a8098e0088b3f0 512 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 176 201 4.8E-6 T 06-07-2017 CAK77_RS00875 e557d1ef4ed2509542a8098e0088b3f0 512 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 9 31 4.8E-6 T 06-07-2017 CAK77_RS00875 e557d1ef4ed2509542a8098e0088b3f0 512 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 176 194 2.0E-5 T 06-07-2017 CAK77_RS00875 e557d1ef4ed2509542a8098e0088b3f0 512 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 10 29 2.0E-5 T 06-07-2017 CAK77_RS02430 4cf4108f0641eca48b030cbddeb9a51e 314 Pfam PF01435 Peptidase family M48 135 217 6.4E-10 T 06-07-2017 IPR001915 Peptidase M48 GO:0004222|GO:0006508 CAK77_RS02430 4cf4108f0641eca48b030cbddeb9a51e 314 Gene3D G3DSA:3.30.2010.10 125 199 1.8E-12 T 06-07-2017 CAK77_RS00160 4cf4108f0641eca48b030cbddeb9a51e 314 Pfam PF01435 Peptidase family M48 135 217 6.4E-10 T 06-07-2017 IPR001915 Peptidase M48 GO:0004222|GO:0006508 CAK77_RS00160 4cf4108f0641eca48b030cbddeb9a51e 314 Gene3D G3DSA:3.30.2010.10 125 199 1.8E-12 T 06-07-2017 CAK77_RS12320 6e15e2e1077a4ad0ad7e64e0ae4e3bc3 92 Pfam PF16525 Haemophore, haem-binding 15 90 1.0E-21 T 06-07-2017 IPR032407 Haemophore, haem-binding GO:0020037 CAK77_RS12320 6e15e2e1077a4ad0ad7e64e0ae4e3bc3 92 TIGRFAM TIGR04529 MTB_hemophore: hemophore-related protein, Rv0203/Rv1174c family 16 91 8.0E-19 T 06-07-2017 IPR032407 Haemophore, haem-binding GO:0020037 CAK77_RS02875 2f8220c07f8aa5fdc8e4edc09d771b8f 105 Gene3D G3DSA:3.30.70.900 1 98 3.2E-33 T 06-07-2017 CAK77_RS02875 2f8220c07f8aa5fdc8e4edc09d771b8f 105 SUPERFAMILY SSF54909 1 98 2.49E-25 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAK77_RS02875 2f8220c07f8aa5fdc8e4edc09d771b8f 105 Pfam PF03992 Antibiotic biosynthesis monooxygenase 3 75 2.7E-20 T 06-07-2017 IPR007138 Antibiotic biosynthesis monooxygenase domain CAK77_RS22535 3720368cbc2cc432bcb7d60ba2f0166c 248 TIGRFAM TIGR04529 MTB_hemophore: hemophore-related protein, Rv0203/Rv1174c family 75 150 1.4E-20 T 06-07-2017 IPR032407 Haemophore, haem-binding GO:0020037 CAK77_RS22535 3720368cbc2cc432bcb7d60ba2f0166c 248 Pfam PF16525 Haemophore, haem-binding 73 149 1.1E-23 T 06-07-2017 IPR032407 Haemophore, haem-binding GO:0020037 CAK77_RS18620 f15d6f18ad4a8fd294a8a6415e994211 151 Pfam PF13577 SnoaL-like domain 2 129 1.5E-8 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain CAK77_RS18620 f15d6f18ad4a8fd294a8a6415e994211 151 Gene3D G3DSA:3.10.450.50 3 141 3.7E-15 T 06-07-2017 IPR032710 NTF2-like domain CAK77_RS18620 f15d6f18ad4a8fd294a8a6415e994211 151 SUPERFAMILY SSF54427 2 139 1.64E-19 T 06-07-2017 IPR032710 NTF2-like domain CAK77_RS00090 8a8629d9a312659cb11e7435c3ccc3b7 190 Pfam PF13376 Bacteriocin-protection, YdeI or OmpD-Associated 128 186 2.7E-21 T 06-07-2017 CAK77_RS19110 c7158f66038f97f77b123cbf4772434f 487 Pfam PF13520 Amino acid permease 49 454 9.4E-36 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CAK77_RS19110 c7158f66038f97f77b123cbf4772434f 487 PIRSF PIRSF006060 32 487 4.1E-58 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CAK77_RS19110 c7158f66038f97f77b123cbf4772434f 487 TIGRFAM TIGR00908 2A0305: ethanolamine permease 33 475 4.7E-156 T 06-07-2017 IPR004757 Ethanolamine permease CAK77_RS12715 43860db4cea0cc6b1081989d6cc45855 239 Gene3D G3DSA:3.40.50.880 47 236 5.1E-59 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAK77_RS12715 43860db4cea0cc6b1081989d6cc45855 239 Pfam PF01965 DJ-1/PfpI family 47 216 5.1E-29 T 06-07-2017 IPR002818 DJ-1/PfpI CAK77_RS12715 43860db4cea0cc6b1081989d6cc45855 239 SUPERFAMILY SSF52317 46 234 5.47E-48 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAK77_RS13285 33e94f58b58c136bcbdfebceebb0249a 607 Pfam PF01642 Methylmalonyl-CoA mutase 46 515 4.3E-125 T 06-07-2017 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CAK77_RS13285 33e94f58b58c136bcbdfebceebb0249a 607 ProSitePatterns PS00544 Methylmalonyl-CoA mutase signature. 357 382 - T 06-07-2017 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CAK77_RS13285 33e94f58b58c136bcbdfebceebb0249a 607 SUPERFAMILY SSF51703 27 510 7.59E-129 T 06-07-2017 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CAK77_RS13285 33e94f58b58c136bcbdfebceebb0249a 607 Gene3D G3DSA:3.40.50.280 474 606 5.8E-41 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CAK77_RS13285 33e94f58b58c136bcbdfebceebb0249a 607 Gene3D G3DSA:3.20.20.240 45 473 2.9E-121 T 06-07-2017 IPR014348 Cobalamin (vitamin B12)-dependent enzyme, catalytic subdomain GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CAK77_RS13285 33e94f58b58c136bcbdfebceebb0249a 607 SUPERFAMILY SSF52242 453 607 2.82E-33 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CAK77_RS13285 33e94f58b58c136bcbdfebceebb0249a 607 TIGRFAM TIGR00642 mmCoA_mut_beta: methylmalonyl-CoA mutase, small subunit 4 607 1.4E-198 T 06-07-2017 IPR004608 Methylmalonyl-CoA mutase, beta chain GO:0004494|GO:0019652|GO:0031419 KEGG: 00280+5.4.99.2|KEGG: 00630+5.4.99.2|KEGG: 00640+5.4.99.2|KEGG: 00720+5.4.99.2|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384 CAK77_RS02180 2b4d5e1ff0515665c051c2b3524704a9 474 Pfam PF07282 Putative transposase DNA-binding domain 348 409 9.6E-17 T 06-07-2017 IPR010095 Transposase IS605, OrfB, C-terminal CAK77_RS02180 2b4d5e1ff0515665c051c2b3524704a9 474 Pfam PF01385 Probable transposase 206 325 2.9E-15 T 06-07-2017 IPR001959 Probable transposase, IS891/IS1136/IS1341 CAK77_RS02180 2b4d5e1ff0515665c051c2b3524704a9 474 Pfam PF12323 Helix-turn-helix domain 10 52 9.0E-11 T 06-07-2017 IPR021027 Transposase, putative, helix-turn-helix domain CAK77_RS05115 43433c5a7342ef5556b7187837a40bd5 394 SUPERFAMILY SSF53756 13 373 1.6E-55 T 06-07-2017 CAK77_RS05115 43433c5a7342ef5556b7187837a40bd5 394 Pfam PF13439 Glycosyltransferase Family 4 50 187 3.1E-7 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 CAK77_RS05115 43433c5a7342ef5556b7187837a40bd5 394 Gene3D G3DSA:3.40.50.2000 202 359 9.5E-27 T 06-07-2017 CAK77_RS05115 43433c5a7342ef5556b7187837a40bd5 394 Pfam PF00534 Glycosyl transferases group 1 203 359 2.7E-28 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 CAK77_RS07335 9e5b88e5c720837f78b46c6812ba6e56 289 Pfam PF14494 Domain of unknown function (DUF4436) 41 287 2.8E-98 T 06-07-2017 IPR027948 Protein of unknown function (DUF4436) CAK77_RS14705 ae2e4bf482248eee15344242a76969c2 222 SUPERFAMILY SSF48498 75 220 8.45E-10 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS14705 ae2e4bf482248eee15344242a76969c2 222 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 57 7.0E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS14705 ae2e4bf482248eee15344242a76969c2 222 SUPERFAMILY SSF46689 4 65 1.85E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS14705 ae2e4bf482248eee15344242a76969c2 222 Gene3D G3DSA:1.10.357.10 3 220 4.3E-37 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS20110 d2b324801c1e2208631b35be69613b1e 271 ProDom PD040376 SCO3349 RV0495C/MT0515 ML2435 MB0506C CGL0407 19 259 4.0E-118 T 06-07-2017 CAK77_RS04875 d7a76b632201b51b58830b1cf2feb7fa 452 PIRSF PIRSF000337 3 451 1.6E-168 T 06-07-2017 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 CAK77_RS04875 d7a76b632201b51b58830b1cf2feb7fa 452 SUPERFAMILY SSF51679 5 447 3.4E-121 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS04875 d7a76b632201b51b58830b1cf2feb7fa 452 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 17 441 3.9E-150 T 06-07-2017 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 CAK77_RS04875 d7a76b632201b51b58830b1cf2feb7fa 452 Gene3D G3DSA:3.20.20.30 2 316 3.0E-127 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS04875 d7a76b632201b51b58830b1cf2feb7fa 452 Gene3D G3DSA:3.20.20.30 358 447 3.0E-127 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS04875 d7a76b632201b51b58830b1cf2feb7fa 452 Pfam PF00296 Luciferase-like monooxygenase 22 397 4.4E-63 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS10465 cbe565645a3e138b241de19ace01a31d 206 Gene3D G3DSA:3.10.450.50 26 170 6.8E-5 T 06-07-2017 IPR032710 NTF2-like domain CAK77_RS10465 cbe565645a3e138b241de19ace01a31d 206 SUPERFAMILY SSF54427 26 162 2.32E-14 T 06-07-2017 IPR032710 NTF2-like domain CAK77_RS10465 cbe565645a3e138b241de19ace01a31d 206 Pfam PF12680 SnoaL-like domain 31 156 6.6E-15 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain CAK77_RS16540 f8ee35913786986f19de3f2e155e9990 168 Pfam PF13404 AsnC-type helix-turn-helix domain 23 63 1.8E-15 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAK77_RS16540 f8ee35913786986f19de3f2e155e9990 168 SUPERFAMILY SSF54909 85 163 8.45E-15 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAK77_RS16540 f8ee35913786986f19de3f2e155e9990 168 Pfam PF01037 Lrp/AsnC ligand binding domain 88 157 2.2E-13 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CAK77_RS16540 f8ee35913786986f19de3f2e155e9990 168 Gene3D G3DSA:1.10.10.10 22 70 8.1E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS16540 f8ee35913786986f19de3f2e155e9990 168 Gene3D G3DSA:3.30.70.920 86 159 4.8E-18 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CAK77_RS16540 f8ee35913786986f19de3f2e155e9990 168 SMART SM00344 23 127 3.9E-32 T 06-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CAK77_RS16540 f8ee35913786986f19de3f2e155e9990 168 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 39 50 9.9E-12 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAK77_RS16540 f8ee35913786986f19de3f2e155e9990 168 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 23 39 9.9E-12 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAK77_RS16540 f8ee35913786986f19de3f2e155e9990 168 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 50 69 9.9E-12 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAK77_RS16540 f8ee35913786986f19de3f2e155e9990 168 SUPERFAMILY SSF46785 22 82 1.02E-10 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS03655 6cb28c14037fe760f12c9c66ee2ef42c 600 Pfam PF10081 Alpha/beta-hydrolase family 297 585 1.2E-123 T 06-07-2017 IPR027787 Alpha/beta-hydrolase, catalytic domain CAK77_RS03655 6cb28c14037fe760f12c9c66ee2ef42c 600 Pfam PF15420 Alpha/beta-hydrolase family N-terminus 66 279 4.5E-68 T 06-07-2017 IPR027788 Alpha/beta-hydrolase, N-terminal domain CAK77_RS12860 28a68f82725daa6807858beb1f938e16 400 SUPERFAMILY SSF51905 267 351 1.39E-54 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS12860 28a68f82725daa6807858beb1f938e16 400 SUPERFAMILY SSF51905 7 177 1.39E-54 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS12860 28a68f82725daa6807858beb1f938e16 400 Gene3D G3DSA:3.50.50.60 7 180 3.0E-45 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS12860 28a68f82725daa6807858beb1f938e16 400 Gene3D G3DSA:3.50.50.60 278 316 3.0E-45 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS12860 28a68f82725daa6807858beb1f938e16 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 156 171 2.1E-21 T 06-07-2017 CAK77_RS12860 28a68f82725daa6807858beb1f938e16 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 8 30 2.1E-21 T 06-07-2017 CAK77_RS12860 28a68f82725daa6807858beb1f938e16 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 280 295 2.1E-21 T 06-07-2017 CAK77_RS12860 28a68f82725daa6807858beb1f938e16 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 295 311 2.1E-21 T 06-07-2017 CAK77_RS12860 28a68f82725daa6807858beb1f938e16 400 Pfam PF01494 FAD binding domain 6 343 2.9E-49 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 CAK77_RS18425 e70cca26972ddbc18b515516629fc55c 184 Pfam PF13599 Pentapeptide repeats (9 copies) 83 152 5.9E-11 T 06-07-2017 IPR001646 Pentapeptide repeat CAK77_RS18425 e70cca26972ddbc18b515516629fc55c 184 SUPERFAMILY SSF141571 5 181 3.01E-42 T 06-07-2017 CAK77_RS18425 e70cca26972ddbc18b515516629fc55c 184 Pfam PF00805 Pentapeptide repeats (8 copies) 50 80 0.0015 T 06-07-2017 IPR001646 Pentapeptide repeat CAK77_RS11990 a8210503a3bce6f7d33555b434a7f1b2 133 Gene3D G3DSA:3.10.450.30 36 131 1.2E-38 T 06-07-2017 IPR016191 Ribonuclease/ribotoxin GO:0003723|GO:0004540 CAK77_RS11990 a8210503a3bce6f7d33555b434a7f1b2 133 SUPERFAMILY SSF53933 36 131 8.5E-33 T 06-07-2017 IPR016191 Ribonuclease/ribotoxin GO:0003723|GO:0004540 CAK77_RS11990 a8210503a3bce6f7d33555b434a7f1b2 133 Pfam PF00545 ribonuclease 44 129 7.7E-29 T 06-07-2017 IPR000026 Guanine-specific ribonuclease N1/T1/U2 GO:0003723|GO:0004521 CAK77_RS01970 922ef6fc534e1c5f412a699465099046 214 Pfam PF13559 Domain of unknown function (DUF4129) 121 190 2.7E-16 T 06-07-2017 IPR025403 Domain of unknown function DUF4129 CAK77_RS10095 72220299aa5b37c738be7aeca03a74ec 539 Pfam PF00501 AMP-binding enzyme 14 433 1.7E-92 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK77_RS10095 72220299aa5b37c738be7aeca03a74ec 539 Gene3D G3DSA:3.40.50.980 42 185 3.3E-27 T 06-07-2017 CAK77_RS10095 72220299aa5b37c738be7aeca03a74ec 539 ProSitePatterns PS00455 Putative AMP-binding domain signature. 178 189 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK77_RS10095 72220299aa5b37c738be7aeca03a74ec 539 Pfam PF13193 AMP-binding enzyme C-terminal domain 442 517 2.7E-16 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAK77_RS10095 72220299aa5b37c738be7aeca03a74ec 539 Gene3D G3DSA:3.40.50.980 186 339 2.5E-38 T 06-07-2017 CAK77_RS10095 72220299aa5b37c738be7aeca03a74ec 539 SUPERFAMILY SSF56801 5 527 8.63E-137 T 06-07-2017 CAK77_RS10095 72220299aa5b37c738be7aeca03a74ec 539 Gene3D G3DSA:3.30.300.30 430 527 1.1E-28 T 06-07-2017 CAK77_RS10095 72220299aa5b37c738be7aeca03a74ec 539 Gene3D G3DSA:2.30.38.10 353 427 6.5E-20 T 06-07-2017 CAK77_RS24380 63b8fe345e75568df455a903990669fc 127 Hamap MF_00227 Ribonuclease P protein component [rnpA]. 2 118 14.764 T 06-07-2017 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CAK77_RS24380 63b8fe345e75568df455a903990669fc 127 SUPERFAMILY SSF54211 2 117 1.82E-17 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAK77_RS24380 63b8fe345e75568df455a903990669fc 127 Pfam PF00825 Ribonuclease P 2 113 1.2E-21 T 06-07-2017 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CAK77_RS24380 63b8fe345e75568df455a903990669fc 127 Gene3D G3DSA:3.30.230.10 2 120 2.4E-25 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CAK77_RS24380 63b8fe345e75568df455a903990669fc 127 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 4 108 2.5E-18 T 06-07-2017 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CAK77_RS20470 257dd10b22e1d96f86bc522f90b2798c 243 Gene3D G3DSA:1.10.357.10 64 209 4.4E-15 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS20470 257dd10b22e1d96f86bc522f90b2798c 243 Pfam PF00440 Bacterial regulatory proteins, tetR family 35 78 1.6E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS20470 257dd10b22e1d96f86bc522f90b2798c 243 SUPERFAMILY SSF48498 102 209 5.93E-21 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS20470 257dd10b22e1d96f86bc522f90b2798c 243 SUPERFAMILY SSF46689 20 88 1.7E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS20470 257dd10b22e1d96f86bc522f90b2798c 243 Gene3D G3DSA:1.10.10.60 19 63 6.4E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS15670 d0cfd651d35eb7f3a83644273a6a31fb 942 Pfam PF03176 MMPL family 54 383 3.4E-104 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 CAK77_RS15670 d0cfd651d35eb7f3a83644273a6a31fb 942 Pfam PF03176 MMPL family 607 933 9.4E-103 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 CAK77_RS15670 d0cfd651d35eb7f3a83644273a6a31fb 942 SUPERFAMILY SSF82866 721 930 6.8E-29 T 06-07-2017 CAK77_RS15670 d0cfd651d35eb7f3a83644273a6a31fb 942 Gene3D G3DSA:1.20.1640.10 725 930 4.9E-23 T 06-07-2017 CAK77_RS15670 d0cfd651d35eb7f3a83644273a6a31fb 942 Gene3D G3DSA:1.20.1640.10 154 358 1.8E-30 T 06-07-2017 CAK77_RS15670 d0cfd651d35eb7f3a83644273a6a31fb 942 SUPERFAMILY SSF82866 134 353 7.72E-27 T 06-07-2017 CAK77_RS15670 d0cfd651d35eb7f3a83644273a6a31fb 942 TIGRFAM TIGR00833 actII: transport protein 23 930 0.0 T 06-07-2017 IPR004707 Membrane transport protein MmpL family GO:0016021 CAK77_RS07885 71c6fa2e8613a6b28e04881bc8fa7386 215 PIRSF PIRSF012637 1 215 3.3E-72 T 06-07-2017 IPR016601 Uncharacterised conserved protein UCP012637 CAK77_RS10805 55fb5113b180b6feb61e256fd5a5e11c 249 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK77_RS10805 55fb5113b180b6feb61e256fd5a5e11c 249 SUPERFAMILY SSF52540 20 220 1.28E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS10805 55fb5113b180b6feb61e256fd5a5e11c 249 Gene3D G3DSA:3.40.50.300 20 228 7.4E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS10805 55fb5113b180b6feb61e256fd5a5e11c 249 Pfam PF00005 ABC transporter 34 165 2.4E-26 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK77_RS10805 55fb5113b180b6feb61e256fd5a5e11c 249 SMART SM00382 43 215 4.3E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS09565 593362f9f1c824d3c4b1bb6fe20b4cb5 290 PIRSF PIRSF000007 11 290 3.2E-145 T 06-07-2017 IPR009152 Ubiquinol-cytochrome-c reductase, cytochrome c subunit GO:0005506|GO:0009055|GO:0016021|GO:0020037 CAK77_RS09565 593362f9f1c824d3c4b1bb6fe20b4cb5 290 SUPERFAMILY SSF46626 39 151 5.01E-18 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK77_RS09565 593362f9f1c824d3c4b1bb6fe20b4cb5 290 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 71 146 8.7E-7 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK77_RS09565 593362f9f1c824d3c4b1bb6fe20b4cb5 290 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 172 245 1.4E-11 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK77_RS09565 593362f9f1c824d3c4b1bb6fe20b4cb5 290 SUPERFAMILY SSF46626 156 246 1.75E-26 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK77_RS09565 593362f9f1c824d3c4b1bb6fe20b4cb5 290 Gene3D G3DSA:1.10.760.10 172 252 8.5E-18 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK77_RS09565 593362f9f1c824d3c4b1bb6fe20b4cb5 290 Gene3D G3DSA:1.10.760.10 70 155 2.5E-20 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAK77_RS16160 9c730ed2afb24e9793f529a19739da4b 111 Pfam PF02566 OsmC-like protein 11 107 6.0E-10 T 06-07-2017 IPR003718 OsmC/Ohr family CAK77_RS16160 9c730ed2afb24e9793f529a19739da4b 111 Gene3D G3DSA:3.30.300.20 11 109 3.7E-10 T 06-07-2017 IPR015946 K homology domain-like, alpha/beta CAK77_RS16160 9c730ed2afb24e9793f529a19739da4b 111 SUPERFAMILY SSF82784 8 110 2.62E-15 T 06-07-2017 IPR003718 OsmC/Ohr family CAK77_RS23550 109d4198794f6e88268a55f807164e76 336 PIRSF PIRSF026166 1 333 1.5E-119 T 06-07-2017 IPR016833 Putative sodium bile acid cotransporter CAK77_RS23550 109d4198794f6e88268a55f807164e76 336 Pfam PF13593 SBF-like CPA transporter family (DUF4137) 11 317 3.7E-89 T 06-07-2017 IPR016833 Putative sodium bile acid cotransporter CAK77_RS13195 2884780f7286a08f8964e65a3177503c 419 TIGRFAM TIGR02079 THD1: threonine dehydratase 11 418 1.8E-177 T 06-07-2017 IPR011820 L-threonine dehydratase biosynthetic IlvA GO:0004794 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 CAK77_RS13195 2884780f7286a08f8964e65a3177503c 419 SUPERFAMILY SSF55021 336 416 1.1E-9 T 06-07-2017 CAK77_RS13195 2884780f7286a08f8964e65a3177503c 419 Gene3D G3DSA:3.40.50.1100 144 331 5.0E-60 T 06-07-2017 CAK77_RS13195 2884780f7286a08f8964e65a3177503c 419 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 326 418 3.1E-26 T 06-07-2017 IPR001721 ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 CAK77_RS13195 2884780f7286a08f8964e65a3177503c 419 SUPERFAMILY SSF53686 10 363 6.02E-96 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAK77_RS13195 2884780f7286a08f8964e65a3177503c 419 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 21 313 9.3E-78 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAK77_RS13195 2884780f7286a08f8964e65a3177503c 419 Gene3D G3DSA:3.40.50.1100 55 143 8.3E-25 T 06-07-2017 CAK77_RS20600 1cc4adc6d4af21e2b6c60de7dfef38e4 377 Pfam PF01757 Acyltransferase family 12 306 5.6E-17 T 06-07-2017 IPR002656 Acyltransferase 3 GO:0016747 CAK77_RS11225 a6f827e7cfb4028bdc1aad8c46dba048 174 Pfam PF04167 Protein of unknown function (DUF402) 50 117 3.3E-17 T 06-07-2017 IPR007295 Domain of unknown function DUF402 CAK77_RS11225 a6f827e7cfb4028bdc1aad8c46dba048 174 PIRSF PIRSF012622 1 172 1.9E-71 T 06-07-2017 IPR014465 Uncharacterised conserved protein UCP012622 CAK77_RS11225 a6f827e7cfb4028bdc1aad8c46dba048 174 Gene3D G3DSA:2.40.380.10 1 161 3.9E-72 T 06-07-2017 IPR007295 Domain of unknown function DUF402 CAK77_RS11225 a6f827e7cfb4028bdc1aad8c46dba048 174 SUPERFAMILY SSF159234 2 166 9.29E-54 T 06-07-2017 CAK77_RS12025 196f9a918d65f2d61e86ca1a89900b3c 184 Pfam PF00877 NlpC/P60 family 48 183 1.3E-22 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain CAK77_RS12025 196f9a918d65f2d61e86ca1a89900b3c 184 SUPERFAMILY SSF54001 29 57 1.81E-23 T 06-07-2017 CAK77_RS12025 196f9a918d65f2d61e86ca1a89900b3c 184 SUPERFAMILY SSF54001 93 176 1.81E-23 T 06-07-2017 CAK77_RS12025 196f9a918d65f2d61e86ca1a89900b3c 184 Gene3D G3DSA:3.90.1720.10 91 179 5.6E-32 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain CAK77_RS12025 196f9a918d65f2d61e86ca1a89900b3c 184 Gene3D G3DSA:3.90.1720.10 28 57 5.6E-32 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain CAK77_RS08530 408c111a81caf60b45d905b7b302cc4c 466 Pfam PF01425 Amidase 24 444 4.4E-104 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAK77_RS08530 408c111a81caf60b45d905b7b302cc4c 466 SUPERFAMILY SSF75304 6 462 7.46E-110 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAK77_RS08530 408c111a81caf60b45d905b7b302cc4c 466 ProSitePatterns PS00571 Amidases signature. 149 180 - T 06-07-2017 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 CAK77_RS08530 408c111a81caf60b45d905b7b302cc4c 466 Gene3D G3DSA:3.90.1300.10 6 460 2.0E-109 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAK77_RS06985 8a125c30baf34aa1bbe5d7e61e8dd923 427 Pfam PF07690 Major Facilitator Superfamily 50 391 1.7E-37 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK77_RS06985 8a125c30baf34aa1bbe5d7e61e8dd923 427 SUPERFAMILY SSF103473 30 421 1.26E-55 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK77_RS06985 8a125c30baf34aa1bbe5d7e61e8dd923 427 ProSitePatterns PS00216 Sugar transport proteins signature 1. 96 113 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CAK77_RS06985 8a125c30baf34aa1bbe5d7e61e8dd923 427 Gene3D G3DSA:1.20.1250.20 39 227 1.6E-27 T 06-07-2017 CAK77_RS06985 8a125c30baf34aa1bbe5d7e61e8dd923 427 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 42 415 5.5E-88 T 06-07-2017 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 CAK77_RS00555 28c5dbf956144addae706420f61f853f 385 Pfam PF00355 Rieske [2Fe-2S] domain 31 115 2.7E-18 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK77_RS00555 28c5dbf956144addae706420f61f853f 385 Gene3D G3DSA:2.102.10.10 29 144 2.9E-32 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK77_RS00555 28c5dbf956144addae706420f61f853f 385 SUPERFAMILY SSF55961 130 346 3.02E-31 T 06-07-2017 CAK77_RS00555 28c5dbf956144addae706420f61f853f 385 SUPERFAMILY SSF50022 25 137 2.75E-31 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK77_RS21960 af6ab6ce45874ec4930bd6241697ac31 142 Pfam PF00011 Hsp20/alpha crystallin family 40 140 2.4E-17 T 06-07-2017 IPR002068 Alpha crystallin/Hsp20 domain CAK77_RS21960 af6ab6ce45874ec4930bd6241697ac31 142 Gene3D G3DSA:2.60.40.790 11 140 2.5E-30 T 06-07-2017 IPR008978 HSP20-like chaperone CAK77_RS21960 af6ab6ce45874ec4930bd6241697ac31 142 SUPERFAMILY SSF49764 13 128 4.19E-28 T 06-07-2017 IPR008978 HSP20-like chaperone CAK77_RS07480 11f89a7ede1f80a485570aa37b541844 120 Pfam PF12823 Domain of unknown function (DUF3817) 27 110 5.4E-26 T 06-07-2017 IPR023845 Domain of unknown function DUF3817, transmembrane CAK77_RS07480 11f89a7ede1f80a485570aa37b541844 120 TIGRFAM TIGR03954 integ_memb_HG: integral membrane protein 28 109 8.8E-26 T 06-07-2017 IPR023845 Domain of unknown function DUF3817, transmembrane CAK77_RS04415 8fe19b71e40aea5cbb0f5f888e865fa3 84 Pfam PF02597 ThiS family 7 84 2.8E-9 T 06-07-2017 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 CAK77_RS04415 8fe19b71e40aea5cbb0f5f888e865fa3 84 SUPERFAMILY SSF54285 4 82 2.4E-13 T 06-07-2017 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp CAK77_RS04415 8fe19b71e40aea5cbb0f5f888e865fa3 84 Gene3D G3DSA:3.10.20.30 4 84 9.2E-19 T 06-07-2017 IPR012675 Beta-grasp domain CAK77_RS23070 5c676b580d23a4260647ffe7bfaf3c6b 417 SUPERFAMILY SSF51395 1 341 5.61E-94 T 06-07-2017 CAK77_RS23070 5c676b580d23a4260647ffe7bfaf3c6b 417 Gene3D G3DSA:3.20.20.70 2 342 3.6E-104 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK77_RS23070 5c676b580d23a4260647ffe7bfaf3c6b 417 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 6 334 7.3E-50 T 06-07-2017 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 CAK77_RS02020 88b385aa22db0f99c4fa2a581281529a 234 Gene3D G3DSA:3.40.50.1110 49 227 6.3E-19 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAK77_RS02020 88b385aa22db0f99c4fa2a581281529a 234 SUPERFAMILY SSF52266 43 227 2.17E-26 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAK77_RS02020 88b385aa22db0f99c4fa2a581281529a 234 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 49 216 2.9E-12 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAK77_RS24265 2248d4cfb2cfb3c50d2167a82e53030f 182 SUPERFAMILY SSF103647 8 69 5.89E-8 T 06-07-2017 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 CAK77_RS24265 2248d4cfb2cfb3c50d2167a82e53030f 182 SUPERFAMILY SSF103647 101 162 1.96E-6 T 06-07-2017 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 CAK77_RS24265 2248d4cfb2cfb3c50d2167a82e53030f 182 Gene3D G3DSA:4.10.1080.10 16 44 6.6E-4 T 06-07-2017 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 CAK77_RS24265 2248d4cfb2cfb3c50d2167a82e53030f 182 Gene3D G3DSA:4.10.1080.10 48 163 3.0E-4 T 06-07-2017 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 CAK77_RS24135 9d90202baec39db9d49109f47f618b5e 363 TIGRFAM TIGR03450 mycothiol_INO1: inositol 1-phosphate synthase 8 361 9.3E-219 T 06-07-2017 IPR017815 Myo-inositol 1-phosphate synthase, actinobacteria CAK77_RS24135 9d90202baec39db9d49109f47f618b5e 363 PIRSF PIRSF015578 1 362 1.4E-96 T 06-07-2017 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 CAK77_RS24135 9d90202baec39db9d49109f47f618b5e 363 SUPERFAMILY SSF55347 194 306 6.15E-36 T 06-07-2017 CAK77_RS24135 9d90202baec39db9d49109f47f618b5e 363 Gene3D G3DSA:3.30.360.10 194 307 4.8E-48 T 06-07-2017 CAK77_RS24135 9d90202baec39db9d49109f47f618b5e 363 SUPERFAMILY SSF51735 7 189 1.51E-93 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS24135 9d90202baec39db9d49109f47f618b5e 363 SUPERFAMILY SSF51735 304 363 1.51E-93 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS24135 9d90202baec39db9d49109f47f618b5e 363 Gene3D G3DSA:3.40.50.720 2 193 4.2E-116 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS24135 9d90202baec39db9d49109f47f618b5e 363 Gene3D G3DSA:3.40.50.720 308 361 4.2E-116 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS24135 9d90202baec39db9d49109f47f618b5e 363 Pfam PF01658 Myo-inositol-1-phosphate synthase 195 307 9.8E-33 T 06-07-2017 IPR013021 Myo-inositol-1-phosphate synthase, GAPDH-like KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 CAK77_RS06210 a23b04fcc86c0a7deca951ffb32014ff 268 Pfam PF03405 Fatty acid desaturase 13 266 1.1E-32 T 06-07-2017 IPR005067 Fatty acid desaturase, type 2 GO:0006631|GO:0045300|GO:0055114 CAK77_RS06210 a23b04fcc86c0a7deca951ffb32014ff 268 PIRSF PIRSF000346 1 267 1.6E-64 T 06-07-2017 IPR005067 Fatty acid desaturase, type 2 GO:0006631|GO:0045300|GO:0055114 CAK77_RS06210 a23b04fcc86c0a7deca951ffb32014ff 268 SUPERFAMILY SSF47240 1 266 7.22E-54 T 06-07-2017 IPR009078 Ferritin-like superfamily CAK77_RS06210 a23b04fcc86c0a7deca951ffb32014ff 268 Gene3D G3DSA:1.10.620.20 1 267 5.8E-70 T 06-07-2017 IPR012348 Ribonucleotide reductase-related GO:0016491|GO:0055114 Reactome: R-HSA-499943 CAK77_RS18800 ab8f959308c4edcbe81995c58311ac82 181 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 5 116 27.005 T 06-07-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS18800 ab8f959308c4edcbe81995c58311ac82 181 TIGRFAM TIGR00059 L17: ribosomal protein bL17 9 116 2.4E-42 T 06-07-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS18800 ab8f959308c4edcbe81995c58311ac82 181 ProSitePatterns PS01167 Ribosomal protein L17 signature. 34 56 - T 06-07-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS18800 ab8f959308c4edcbe81995c58311ac82 181 SUPERFAMILY SSF64263 1 118 1.07E-47 T 06-07-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS18800 ab8f959308c4edcbe81995c58311ac82 181 Pfam PF01196 Ribosomal protein L17 21 116 4.3E-37 T 06-07-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS18800 ab8f959308c4edcbe81995c58311ac82 181 Gene3D G3DSA:3.90.1030.10 3 117 1.3E-47 T 06-07-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS00195 958d2330f5d26376ed7d58a8fc6605ec 243 Pfam PF06912 Protein of unknown function (DUF1275) 7 195 1.1E-23 T 06-07-2017 IPR010699 Protein of unknown function DUF1275 CAK77_RS17055 96edd34e11e8130a0f5543c459a8f94c 207 Gene3D G3DSA:1.10.357.10 60 206 3.2E-19 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS17055 96edd34e11e8130a0f5543c459a8f94c 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 66 2.4E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS17055 96edd34e11e8130a0f5543c459a8f94c 207 SUPERFAMILY SSF46689 11 78 6.98E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS17055 96edd34e11e8130a0f5543c459a8f94c 207 Gene3D G3DSA:1.10.10.60 8 59 9.9E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS17055 96edd34e11e8130a0f5543c459a8f94c 207 SUPERFAMILY SSF48498 88 206 1.49E-24 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS05800 4c7558cee19b75f4368737c318d3c418 286 Pfam PF01925 Sulfite exporter TauE/SafE 151 277 6.3E-22 T 06-07-2017 IPR002781 Transmembrane protein TauE-like GO:0016021 CAK77_RS05800 4c7558cee19b75f4368737c318d3c418 286 Pfam PF01925 Sulfite exporter TauE/SafE 6 119 1.7E-14 T 06-07-2017 IPR002781 Transmembrane protein TauE-like GO:0016021 CAK77_RS17190 dba792072a6294af73c2800087b33687 427 Pfam PF00083 Sugar (and other) transporter 262 403 4.9E-6 T 06-07-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CAK77_RS17190 dba792072a6294af73c2800087b33687 427 Gene3D G3DSA:1.20.1250.20 23 199 1.8E-36 T 06-07-2017 CAK77_RS17190 dba792072a6294af73c2800087b33687 427 Gene3D G3DSA:1.20.1250.20 221 405 2.3E-31 T 06-07-2017 CAK77_RS17190 dba792072a6294af73c2800087b33687 427 PRINTS PR01035 Tetracycline resistance protein signature 34 50 6.1E-14 T 06-07-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CAK77_RS17190 dba792072a6294af73c2800087b33687 427 PRINTS PR01035 Tetracycline resistance protein signature 149 171 6.1E-14 T 06-07-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CAK77_RS17190 dba792072a6294af73c2800087b33687 427 PRINTS PR01035 Tetracycline resistance protein signature 177 197 6.1E-14 T 06-07-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CAK77_RS17190 dba792072a6294af73c2800087b33687 427 PRINTS PR01035 Tetracycline resistance protein signature 289 310 6.1E-14 T 06-07-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CAK77_RS17190 dba792072a6294af73c2800087b33687 427 PRINTS PR01035 Tetracycline resistance protein signature 378 397 6.1E-14 T 06-07-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CAK77_RS17190 dba792072a6294af73c2800087b33687 427 Pfam PF07690 Major Facilitator Superfamily 29 249 6.5E-30 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK77_RS17190 dba792072a6294af73c2800087b33687 427 SUPERFAMILY SSF103473 16 406 6.02E-71 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK77_RS01140 361116cb41504bd5e312c522ff524f54 274 SUPERFAMILY SSF53474 3 271 7.09E-43 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS01140 361116cb41504bd5e312c522ff524f54 274 Pfam PF12697 Alpha/beta hydrolase family 22 264 1.5E-12 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS01140 361116cb41504bd5e312c522ff524f54 274 Gene3D G3DSA:3.40.50.1820 9 271 2.7E-40 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS06040 7a3af54330ad5d0c5034ccc06f0f55ce 289 Pfam PF02585 GlcNAc-PI de-N-acetylase 7 152 7.7E-26 T 06-07-2017 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 CAK77_RS06040 7a3af54330ad5d0c5034ccc06f0f55ce 289 SUPERFAMILY SSF102588 3 287 6.8E-73 T 06-07-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CAK77_RS06040 7a3af54330ad5d0c5034ccc06f0f55ce 289 Hamap MF_01482 Mycothiol S-conjugate amidase [mca]. 7 287 52.442 T 06-07-2017 IPR017811 Mycothiol S-conjugate amidase Mca GO:0010126 KEGG: 00311+3.5.1.11 CAK77_RS06040 7a3af54330ad5d0c5034ccc06f0f55ce 289 Gene3D G3DSA:3.40.50.10320 2 288 3.1E-88 T 06-07-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CAK77_RS06040 7a3af54330ad5d0c5034ccc06f0f55ce 289 TIGRFAM TIGR03446 mycothiol_Mca: mycothiol conjugate amidase Mca 4 286 1.3E-146 T 06-07-2017 IPR017811 Mycothiol S-conjugate amidase Mca GO:0010126 KEGG: 00311+3.5.1.11 CAK77_RS11935 bab4b6007dc772b6e479afaefab14d35 150 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 8 147 5.5E-9 T 06-07-2017 IPR019587 Polyketide cyclase/dehydrase CAK77_RS11935 bab4b6007dc772b6e479afaefab14d35 150 Gene3D G3DSA:3.30.530.20 4 149 7.2E-12 T 06-07-2017 IPR023393 START-like domain CAK77_RS11935 bab4b6007dc772b6e479afaefab14d35 150 SUPERFAMILY SSF55961 4 148 4.59E-22 T 06-07-2017 CAK77_RS09330 eda307f367cfcc05c078b55c1db8dee4 180 Pfam PF16525 Haemophore, haem-binding 33 109 2.5E-25 T 06-07-2017 IPR032407 Haemophore, haem-binding GO:0020037 CAK77_RS09330 eda307f367cfcc05c078b55c1db8dee4 180 TIGRFAM TIGR04529 MTB_hemophore: hemophore-related protein, Rv0203/Rv1174c family 34 109 2.3E-22 T 06-07-2017 IPR032407 Haemophore, haem-binding GO:0020037 CAK77_RS09430 087e8122cb318b259239e353c04566da 329 SUPERFAMILY SSF102114 32 306 2.22E-62 T 06-07-2017 CAK77_RS09430 087e8122cb318b259239e353c04566da 329 Pfam PF04055 Radical SAM superfamily 77 230 1.9E-11 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 CAK77_RS09430 087e8122cb318b259239e353c04566da 329 PIRSF PIRSF005963 2 313 8.5E-120 T 06-07-2017 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CAK77_RS09430 087e8122cb318b259239e353c04566da 329 Hamap MF_00206 Lipoyl synthase [lipA]. 1 304 137.877 T 06-07-2017 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CAK77_RS09430 087e8122cb318b259239e353c04566da 329 Pfam PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family 21 57 1.5E-7 T 06-07-2017 IPR031691 Lipoyl synthase, N-terminal KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CAK77_RS09430 087e8122cb318b259239e353c04566da 329 TIGRFAM TIGR00510 lipA: lipoyl synthase 14 301 1.2E-96 T 06-07-2017 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CAK77_RS09430 087e8122cb318b259239e353c04566da 329 SMART SM00729 68 274 3.4E-12 T 06-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CAK77_RS09430 087e8122cb318b259239e353c04566da 329 Gene3D G3DSA:3.20.20.70 35 298 4.6E-65 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK77_RS21880 10bbaba1b834e160225df61acece9508 290 Gene3D G3DSA:3.40.190.10 89 195 1.5E-32 T 06-07-2017 CAK77_RS21880 10bbaba1b834e160225df61acece9508 290 TIGRFAM TIGR03298 argP: transcriptional regulator, ArgP family 3 284 1.9E-101 T 06-07-2017 IPR017685 HTH-type transcriptional regulator ArgP CAK77_RS21880 10bbaba1b834e160225df61acece9508 290 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 62 1.6E-16 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK77_RS21880 10bbaba1b834e160225df61acece9508 290 SUPERFAMILY SSF53850 101 283 5.07E-14 T 06-07-2017 CAK77_RS21880 10bbaba1b834e160225df61acece9508 290 Pfam PF03466 LysR substrate binding domain 110 281 1.3E-9 T 06-07-2017 IPR005119 LysR, substrate-binding CAK77_RS21880 10bbaba1b834e160225df61acece9508 290 SUPERFAMILY SSF46785 3 91 1.27E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS21880 10bbaba1b834e160225df61acece9508 290 Gene3D G3DSA:1.10.10.10 4 83 1.4E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS10985 d1a3029e937768be0a7532740f5d8a7d 280 SUPERFAMILY SSF53335 10 268 6.85E-60 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS10985 d1a3029e937768be0a7532740f5d8a7d 280 Gene3D G3DSA:3.40.50.150 64 200 3.1E-14 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS10985 d1a3029e937768be0a7532740f5d8a7d 280 Pfam PF04072 Leucine carboxyl methyltransferase 13 189 2.0E-44 T 06-07-2017 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 CAK77_RS10985 d1a3029e937768be0a7532740f5d8a7d 280 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 11 265 1.4E-43 T 06-07-2017 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 CAK77_RS22605 549794a1a1d2857af35cf77b8670cc10 100 Pfam PF02583 Metal-sensitive transcriptional repressor 15 95 6.2E-30 T 06-07-2017 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 CAK77_RS03050 6ece5d8eab1f2ea00be3180792f87424 370 Pfam PF04371 Porphyromonas-type peptidyl-arginine deiminase 42 369 1.9E-107 T 06-07-2017 IPR007466 Peptidyl-arginine deiminase, Porphyromonas-type GO:0004668|GO:0009446 KEGG: 00330+3.5.3.12|MetaCyc: PWY-43 CAK77_RS03050 6ece5d8eab1f2ea00be3180792f87424 370 SUPERFAMILY SSF55909 38 370 7.67E-114 T 06-07-2017 CAK77_RS03050 6ece5d8eab1f2ea00be3180792f87424 370 Gene3D G3DSA:3.75.10.10 37 369 9.5E-122 T 06-07-2017 CAK77_RS20570 9df37e430a9347f842a85a6cfc37bf28 417 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 3 72 4.1E-6 T 06-07-2017 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CAK77_RS20570 9df37e430a9347f842a85a6cfc37bf28 417 Gene3D G3DSA:3.40.50.2000 256 388 4.2E-8 T 06-07-2017 CAK77_RS20570 9df37e430a9347f842a85a6cfc37bf28 417 Gene3D G3DSA:3.40.50.2000 1 255 1.7E-56 T 06-07-2017 CAK77_RS20570 9df37e430a9347f842a85a6cfc37bf28 417 SUPERFAMILY SSF53756 1 414 7.07E-82 T 06-07-2017 CAK77_RS14100 e29c76da0ce406317a283fa872321dc2 358 Gene3D G3DSA:1.10.10.10 274 344 2.1E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS14100 e29c76da0ce406317a283fa872321dc2 358 Gene3D G3DSA:3.40.50.300 38 191 1.5E-29 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS14100 e29c76da0ce406317a283fa872321dc2 358 SUPERFAMILY SSF46785 273 347 1.5E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS14100 e29c76da0ce406317a283fa872321dc2 358 SUPERFAMILY SSF52540 37 267 2.44E-49 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS14100 e29c76da0ce406317a283fa872321dc2 358 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 28 252 3.0E-105 T 06-07-2017 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 CAK77_RS14100 e29c76da0ce406317a283fa872321dc2 358 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 287 341 4.0E-22 T 06-07-2017 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 CAK77_RS14100 e29c76da0ce406317a283fa872321dc2 358 Gene3D G3DSA:1.10.8.60 200 272 1.2E-30 T 06-07-2017 CAK77_RS14100 e29c76da0ce406317a283fa872321dc2 358 SMART SM00382 68 201 8.0E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS14100 e29c76da0ce406317a283fa872321dc2 358 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 358 158.454 T 06-07-2017 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 CAK77_RS14100 e29c76da0ce406317a283fa872321dc2 358 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 270 343 2.1E-29 T 06-07-2017 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 CAK77_RS14100 e29c76da0ce406317a283fa872321dc2 358 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 40 343 3.6E-138 T 06-07-2017 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 CAK77_RS20025 23a8dcadbbfcc601cc5c16e147c01ef9 477 Pfam PF06863 Protein of unknown function (DUF1254) 79 209 1.0E-43 T 06-07-2017 IPR010679 Domain of unknown function DUF1254 CAK77_RS20025 23a8dcadbbfcc601cc5c16e147c01ef9 477 Gene3D G3DSA:2.60.120.600 308 476 5.6E-60 T 06-07-2017 IPR010621 Domain of unknown function DUF1214 CAK77_RS20025 23a8dcadbbfcc601cc5c16e147c01ef9 477 SUPERFAMILY SSF160935 13 476 1.57E-134 T 06-07-2017 CAK77_RS20025 23a8dcadbbfcc601cc5c16e147c01ef9 477 Gene3D G3DSA:1.10.3360.10 209 307 3.6E-18 T 06-07-2017 IPR023289 VPA0735-like domain CAK77_RS20025 23a8dcadbbfcc601cc5c16e147c01ef9 477 Gene3D G3DSA:2.60.40.1610 95 208 4.7E-16 T 06-07-2017 IPR010679 Domain of unknown function DUF1254 CAK77_RS20025 23a8dcadbbfcc601cc5c16e147c01ef9 477 Pfam PF06742 Protein of unknown function (DUF1214) 350 458 9.8E-38 T 06-07-2017 IPR010621 Domain of unknown function DUF1214 CAK77_RS01650 5d0b1cff20d157502f8a9e34f1b1136d 145 SUPERFAMILY SSF46785 7 141 4.07E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS01650 5d0b1cff20d157502f8a9e34f1b1136d 145 Gene3D G3DSA:1.10.10.10 5 143 2.9E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS01650 5d0b1cff20d157502f8a9e34f1b1136d 145 Pfam PF12802 MarR family 33 91 1.1E-6 T 06-07-2017 CAK77_RS01650 5d0b1cff20d157502f8a9e34f1b1136d 145 SMART SM00347 27 127 7.4E-16 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK77_RS19770 94b245940740ebcd74a01489c0fff60f 128 Gene3D G3DSA:3.10.180.10 8 125 9.0E-21 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK77_RS19770 94b245940740ebcd74a01489c0fff60f 128 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 111 2.2E-10 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CAK77_RS19770 94b245940740ebcd74a01489c0fff60f 128 SUPERFAMILY SSF54593 7 117 2.28E-20 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK77_RS11905 1b607df5607dc39958697c0ec01f23f8 475 SUPERFAMILY SSF53474 198 466 1.33E-25 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS11905 1b607df5607dc39958697c0ec01f23f8 475 Gene3D G3DSA:3.40.50.1820 383 470 5.7E-39 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS11905 1b607df5607dc39958697c0ec01f23f8 475 Gene3D G3DSA:3.40.50.1820 177 340 5.7E-39 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS11905 1b607df5607dc39958697c0ec01f23f8 475 Pfam PF00756 Putative esterase 203 362 3.9E-12 T 06-07-2017 IPR000801 Putative esterase Reactome: R-HSA-156590 CAK77_RS21400 a5c415c13f0341f3dec2ed5e2205834b 224 SUPERFAMILY SSF75217 58 218 9.16E-38 T 06-07-2017 IPR029028 Alpha/beta knot methyltransferases CAK77_RS21400 a5c415c13f0341f3dec2ed5e2205834b 224 Pfam PF00588 SpoU rRNA Methylase family 75 211 2.1E-23 T 06-07-2017 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CAK77_RS21400 a5c415c13f0341f3dec2ed5e2205834b 224 Gene3D G3DSA:3.40.1280.10 56 218 1.0E-39 T 06-07-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CAK77_RS00990 a8e2b106e4915b78b281f374811bf5e3 265 SMART SM00563 37 153 7.9E-34 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CAK77_RS00990 a8e2b106e4915b78b281f374811bf5e3 265 Gene3D G3DSA:3.40.1130.10 27 192 1.8E-19 T 06-07-2017 CAK77_RS00990 a8e2b106e4915b78b281f374811bf5e3 265 Pfam PF01553 Acyltransferase 23 150 2.8E-31 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CAK77_RS00990 a8e2b106e4915b78b281f374811bf5e3 265 SUPERFAMILY SSF69593 17 201 1.44E-32 T 06-07-2017 CAK77_RS00485 5de07f98cbe83d7f92ebd6002e485bbb 242 Gene3D G3DSA:1.10.10.60 200 238 4.6E-8 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS00485 5de07f98cbe83d7f92ebd6002e485bbb 242 SMART SM00342 154 236 1.8E-15 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK77_RS00485 5de07f98cbe83d7f92ebd6002e485bbb 242 SUPERFAMILY SSF46689 139 188 3.23E-5 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS00485 5de07f98cbe83d7f92ebd6002e485bbb 242 Pfam PF12833 Helix-turn-helix domain 160 237 1.3E-17 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK77_RS00485 5de07f98cbe83d7f92ebd6002e485bbb 242 Gene3D G3DSA:1.10.10.60 137 192 2.9E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS00485 5de07f98cbe83d7f92ebd6002e485bbb 242 SUPERFAMILY SSF46689 200 238 6.27E-6 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS12955 e1278b373bc8ccc37f5c6d88ae738b5a 548 Gene3D G3DSA:3.40.50.300 351 534 4.4E-42 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS12955 e1278b373bc8ccc37f5c6d88ae738b5a 548 TIGRFAM TIGR02868 CydC: thiol reductant ABC exporter, CydC subunit 16 531 4.5E-160 T 06-07-2017 IPR014223 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC GO:0006810|GO:0016021|GO:0042626 CAK77_RS12955 e1278b373bc8ccc37f5c6d88ae738b5a 548 Pfam PF00005 ABC transporter 351 496 1.4E-24 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK77_RS12955 e1278b373bc8ccc37f5c6d88ae738b5a 548 SMART SM00382 357 546 6.2E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS12955 e1278b373bc8ccc37f5c6d88ae738b5a 548 ProSitePatterns PS00211 ABC transporters family signature. 469 483 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK77_RS12955 e1278b373bc8ccc37f5c6d88ae738b5a 548 SUPERFAMILY SSF90123 18 313 1.26E-22 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAK77_RS12955 e1278b373bc8ccc37f5c6d88ae738b5a 548 SUPERFAMILY SSF52540 346 533 9.61E-41 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS12955 e1278b373bc8ccc37f5c6d88ae738b5a 548 Gene3D G3DSA:1.20.1560.10 20 313 6.0E-14 T 06-07-2017 CAK77_RS02635 b449a7c4a9735fafe321bd57fea7ed79 132 Pfam PF10066 Uncharacterized conserved protein (DUF2304) 4 108 5.7E-28 T 06-07-2017 IPR019277 Protein of unknown function DUF2304 CAK77_RS23330 20162275ac9cac59fff68c0d54a0753a 195 SUPERFAMILY SSF53756 2 187 1.97E-23 T 06-07-2017 CAK77_RS23330 20162275ac9cac59fff68c0d54a0753a 195 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 5 56 3.3E-6 T 06-07-2017 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CAK77_RS23330 20162275ac9cac59fff68c0d54a0753a 195 Gene3D G3DSA:3.40.50.2000 5 190 8.0E-26 T 06-07-2017 CAK77_RS14040 ddf1a00f6405a81239492a5bea4a5264 116 SUPERFAMILY SSF110857 8 115 8.24E-13 T 06-07-2017 IPR013024 Butirosin biosynthesis, BtrG-like CAK77_RS14040 ddf1a00f6405a81239492a5bea4a5264 116 Pfam PF06094 Gamma-glutamyl cyclotransferase, AIG2-like 9 115 3.6E-11 T 06-07-2017 IPR009288 Gamma-glutamylcyclotransferase, AIG2-like CAK77_RS14040 ddf1a00f6405a81239492a5bea4a5264 116 Gene3D G3DSA:3.10.490.10 7 114 3.1E-8 T 06-07-2017 IPR013024 Butirosin biosynthesis, BtrG-like CAK77_RS08395 d7cb5934172b35dfe0f2f6dd356ad782 417 SUPERFAMILY SSF51905 11 182 7.48E-54 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS08395 d7cb5934172b35dfe0f2f6dd356ad782 417 SUPERFAMILY SSF51905 274 363 7.48E-54 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS08395 d7cb5934172b35dfe0f2f6dd356ad782 417 Gene3D G3DSA:3.50.50.60 275 350 2.1E-42 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS08395 d7cb5934172b35dfe0f2f6dd356ad782 417 Gene3D G3DSA:3.50.50.60 10 187 2.1E-42 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS08395 d7cb5934172b35dfe0f2f6dd356ad782 417 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 302 318 2.0E-19 T 06-07-2017 CAK77_RS08395 d7cb5934172b35dfe0f2f6dd356ad782 417 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 161 176 2.0E-19 T 06-07-2017 CAK77_RS08395 d7cb5934172b35dfe0f2f6dd356ad782 417 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 287 302 2.0E-19 T 06-07-2017 CAK77_RS08395 d7cb5934172b35dfe0f2f6dd356ad782 417 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 11 33 2.0E-19 T 06-07-2017 CAK77_RS08395 d7cb5934172b35dfe0f2f6dd356ad782 417 Pfam PF01494 FAD binding domain 11 327 4.9E-52 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 CAK77_RS18085 19c69f799159b2ee003dfbb56b2d3e8c 250 Gene3D G3DSA:3.40.50.150 53 237 4.2E-35 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS18085 19c69f799159b2ee003dfbb56b2d3e8c 250 SUPERFAMILY SSF53335 71 240 3.72E-38 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS18085 19c69f799159b2ee003dfbb56b2d3e8c 250 Pfam PF08241 Methyltransferase domain 94 190 1.1E-21 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CAK77_RS23590 47eb75ac8d49952ba81c8761c447e06c 270 Gene3D G3DSA:3.20.20.60 4 221 4.7E-54 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAK77_RS23590 47eb75ac8d49952ba81c8761c447e06c 270 SUPERFAMILY SSF51621 5 221 5.23E-48 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAK77_RS23590 47eb75ac8d49952ba81c8761c447e06c 270 PIRSF PIRSF015582 2 269 2.7E-54 T 06-07-2017 IPR011206 Citrate lyase beta subunit-like CAK77_RS23590 47eb75ac8d49952ba81c8761c447e06c 270 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 11 207 2.7E-24 T 06-07-2017 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 CAK77_RS23105 fea5385a42073ca46dd56b022d7cab19 458 SUPERFAMILY SSF51419 56 300 7.33E-19 T 06-07-2017 IPR029066 PLP-binding barrel CAK77_RS23105 fea5385a42073ca46dd56b022d7cab19 458 Gene3D G3DSA:3.20.20.10 58 272 7.8E-6 T 06-07-2017 IPR029066 PLP-binding barrel CAK77_RS23105 fea5385a42073ca46dd56b022d7cab19 458 Pfam PF01168 Alanine racemase, N-terminal domain 55 296 4.0E-9 T 06-07-2017 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAK77_RS07040 fae7bd920e16707ed28c0d67c833e7bf 413 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 356 365 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CAK77_RS07040 fae7bd920e16707ed28c0d67c833e7bf 413 Gene3D G3DSA:1.10.630.10 14 412 2.3E-107 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS07040 fae7bd920e16707ed28c0d67c833e7bf 413 SUPERFAMILY SSF48264 19 412 3.93E-84 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS07040 fae7bd920e16707ed28c0d67c833e7bf 413 Pfam PF00067 Cytochrome P450 45 383 2.7E-15 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS07040 fae7bd920e16707ed28c0d67c833e7bf 413 PRINTS PR00359 B-class P450 signature 304 331 2.2E-42 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS07040 fae7bd920e16707ed28c0d67c833e7bf 413 PRINTS PR00359 B-class P450 signature 142 158 2.2E-42 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS07040 fae7bd920e16707ed28c0d67c833e7bf 413 PRINTS PR00359 B-class P450 signature 204 226 2.2E-42 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS07040 fae7bd920e16707ed28c0d67c833e7bf 413 PRINTS PR00359 B-class P450 signature 159 174 2.2E-42 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS07040 fae7bd920e16707ed28c0d67c833e7bf 413 PRINTS PR00359 B-class P450 signature 287 298 2.2E-42 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS07040 fae7bd920e16707ed28c0d67c833e7bf 413 PRINTS PR00359 B-class P450 signature 354 363 2.2E-42 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS07040 fae7bd920e16707ed28c0d67c833e7bf 413 PRINTS PR00359 B-class P450 signature 96 107 2.2E-42 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS07040 fae7bd920e16707ed28c0d67c833e7bf 413 PRINTS PR00359 B-class P450 signature 363 374 2.2E-42 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS06480 689885634c7d8aed28fdac84764c9444 173 Gene3D G3DSA:3.30.70.1280 1 86 3.3E-28 T 06-07-2017 CAK77_RS06480 689885634c7d8aed28fdac84764c9444 173 Pfam PF08002 Protein of unknown function (DUF1697) 1 134 3.9E-38 T 06-07-2017 IPR012545 Protein of unknown function DUF1697 CAK77_RS06480 689885634c7d8aed28fdac84764c9444 173 PIRSF PIRSF008502 1 173 2.2E-51 T 06-07-2017 IPR012545 Protein of unknown function DUF1697 CAK77_RS06480 689885634c7d8aed28fdac84764c9444 173 SUPERFAMILY SSF160379 1 172 7.19E-49 T 06-07-2017 CAK77_RS20245 6b13da3d3c4bf0acf924965ce6f2a241 185 SUPERFAMILY SSF55961 58 177 7.19E-10 T 06-07-2017 CAK77_RS20245 6b13da3d3c4bf0acf924965ce6f2a241 185 Gene3D G3DSA:3.30.530.20 56 180 4.1E-6 T 06-07-2017 IPR023393 START-like domain CAK77_RS20245 6b13da3d3c4bf0acf924965ce6f2a241 185 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 57 175 3.0E-8 T 06-07-2017 IPR019587 Polyketide cyclase/dehydrase CAK77_RS07700 f8c774c7b3193391f27e930a701d2681 157 Gene3D G3DSA:3.10.129.10 1 142 3.3E-20 T 06-07-2017 IPR029069 HotDog domain CAK77_RS07700 f8c774c7b3193391f27e930a701d2681 157 PIRSF PIRSF018072 1 149 1.3E-44 T 06-07-2017 IPR016709 Uncharacterised protein family UPF0336 CAK77_RS07700 f8c774c7b3193391f27e930a701d2681 157 SUPERFAMILY SSF54637 7 146 1.74E-30 T 06-07-2017 IPR029069 HotDog domain CAK77_RS07700 f8c774c7b3193391f27e930a701d2681 157 Pfam PF13452 N-terminal half of MaoC dehydratase 7 136 5.4E-23 T 06-07-2017 CAK77_RS11995 4658bec739ba4313fc635eb097eb9cae 100 SUPERFAMILY SSF52038 3 84 1.96E-15 T 06-07-2017 IPR000468 Barstar (barnase inhibitor) CAK77_RS11995 4658bec739ba4313fc635eb097eb9cae 100 Gene3D G3DSA:3.30.370.10 1 84 3.2E-20 T 06-07-2017 IPR000468 Barstar (barnase inhibitor) CAK77_RS11995 4658bec739ba4313fc635eb097eb9cae 100 Pfam PF01337 Barstar (barnase inhibitor) 6 85 8.4E-18 T 06-07-2017 IPR000468 Barstar (barnase inhibitor) CAK77_RS19855 1b3a138c1c4da9e0f203e3b72ed72fd9 173 Pfam PF04075 Domain of unknown function (DUF385) 56 159 5.7E-10 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CAK77_RS06390 5e2a20d38dbffa641b86adcbc806cc3d 439 SUPERFAMILY SSF103473 31 423 1.57E-49 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK77_RS06390 5e2a20d38dbffa641b86adcbc806cc3d 439 Gene3D G3DSA:1.20.1250.20 30 212 1.2E-28 T 06-07-2017 CAK77_RS06390 5e2a20d38dbffa641b86adcbc806cc3d 439 Pfam PF07690 Major Facilitator Superfamily 34 383 5.9E-30 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK77_RS06390 5e2a20d38dbffa641b86adcbc806cc3d 439 PRINTS PR01035 Tetracycline resistance protein signature 154 176 3.4E-5 T 06-07-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CAK77_RS06390 5e2a20d38dbffa641b86adcbc806cc3d 439 PRINTS PR01035 Tetracycline resistance protein signature 39 55 3.4E-5 T 06-07-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CAK77_RS06390 5e2a20d38dbffa641b86adcbc806cc3d 439 PRINTS PR01035 Tetracycline resistance protein signature 298 319 3.4E-5 T 06-07-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CAK77_RS06390 5e2a20d38dbffa641b86adcbc806cc3d 439 Gene3D G3DSA:1.20.1250.20 224 422 1.4E-13 T 06-07-2017 CAK77_RS10825 e9821f057f3a3b3de60ce1a08249732e 144 Gene3D G3DSA:2.30.110.10 5 138 5.3E-18 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS10825 e9821f057f3a3b3de60ce1a08249732e 144 SUPERFAMILY SSF50475 3 140 4.86E-22 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS10825 e9821f057f3a3b3de60ce1a08249732e 144 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 7 90 7.9E-9 T 06-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAK77_RS09485 e6189df05cbbe8d1ed1851d3a6abd708 340 SUPERFAMILY SSF52733 12 338 4.19E-109 T 06-07-2017 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CAK77_RS09485 e6189df05cbbe8d1ed1851d3a6abd708 340 Hamap MF_00230 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase [cobT]. 17 339 35.469 T 06-07-2017 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CAK77_RS09485 e6189df05cbbe8d1ed1851d3a6abd708 340 TIGRFAM TIGR03160 cobT_DBIPRT: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 19 337 6.4E-117 T 06-07-2017 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CAK77_RS09485 e6189df05cbbe8d1ed1851d3a6abd708 340 Pfam PF02277 Phosphoribosyltransferase 16 337 6.9E-128 T 06-07-2017 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CAK77_RS09485 e6189df05cbbe8d1ed1851d3a6abd708 340 Gene3D G3DSA:1.10.1610.10 12 77 1.2E-30 T 06-07-2017 IPR023195 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CAK77_RS09485 e6189df05cbbe8d1ed1851d3a6abd708 340 Gene3D G3DSA:3.40.50.10210 78 320 2.5E-98 T 06-07-2017 CAK77_RS05430 a2c43b741a7b2aaeb3f3989a6cb61ef0 223 Gene3D G3DSA:2.10.300.10 109 162 2.4E-24 T 06-07-2017 CAK77_RS05430 a2c43b741a7b2aaeb3f3989a6cb61ef0 223 SUPERFAMILY SSF56959 38 222 3.2E-66 T 06-07-2017 IPR016183 Leukocidin/porin GO:0005576|GO:0051715 CAK77_RS05430 a2c43b741a7b2aaeb3f3989a6cb61ef0 223 Gene3D G3DSA:2.60.40.1650 39 108 3.9E-52 T 06-07-2017 CAK77_RS05430 a2c43b741a7b2aaeb3f3989a6cb61ef0 223 Gene3D G3DSA:2.60.40.1650 163 222 3.9E-52 T 06-07-2017 CAK77_RS05430 a2c43b741a7b2aaeb3f3989a6cb61ef0 223 Pfam PF09203 MspA 50 221 3.4E-39 T 06-07-2017 IPR015286 Porin family, mycobacterial-type CAK77_RS12235 4ca1307904b073f73ee3c47e6c595410 140 Pfam PF04120 Low affinity iron permease 24 135 1.3E-21 T 06-07-2017 IPR007251 Low affinity iron permease, Fet4 GO:0055085 CAK77_RS12870 6a53758456576ccbab26c4e4fb616d0b 132 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 119 3.5E-5 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CAK77_RS12870 6a53758456576ccbab26c4e4fb616d0b 132 Gene3D G3DSA:3.10.180.10 5 127 3.9E-23 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK77_RS12870 6a53758456576ccbab26c4e4fb616d0b 132 SUPERFAMILY SSF54593 4 124 1.26E-22 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK77_RS21385 479ab2df9c6164a8e7f79b224511d50e 235 Pfam PF09335 SNARE associated Golgi protein 49 185 2.9E-19 T 06-07-2017 IPR032816 SNARE associated Golgi protein CAK77_RS15580 835bc22c040738b51396af0d71ab3fb6 413 SUPERFAMILY SSF46458 19 161 8.48E-31 T 06-07-2017 IPR009050 Globin-like CAK77_RS15580 835bc22c040738b51396af0d71ab3fb6 413 Gene3D G3DSA:3.40.50.80 276 405 4.4E-28 T 06-07-2017 CAK77_RS15580 835bc22c040738b51396af0d71ab3fb6 413 Gene3D G3DSA:2.40.30.10 172 275 6.0E-26 T 06-07-2017 CAK77_RS15580 835bc22c040738b51396af0d71ab3fb6 413 PRINTS PR00410 Phenol hydroxylase reductase family signature 202 214 9.8E-7 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 CAK77_RS15580 835bc22c040738b51396af0d71ab3fb6 413 PRINTS PR00410 Phenol hydroxylase reductase family signature 285 304 9.8E-7 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 CAK77_RS15580 835bc22c040738b51396af0d71ab3fb6 413 PRINTS PR00410 Phenol hydroxylase reductase family signature 373 381 9.8E-7 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 CAK77_RS15580 835bc22c040738b51396af0d71ab3fb6 413 Pfam PF00042 Globin 27 122 1.7E-5 T 06-07-2017 IPR000971 Globin GO:0019825|GO:0020037 CAK77_RS15580 835bc22c040738b51396af0d71ab3fb6 413 Pfam PF00970 Oxidoreductase FAD-binding domain 176 275 5.2E-11 T 06-07-2017 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 CAK77_RS15580 835bc22c040738b51396af0d71ab3fb6 413 SUPERFAMILY SSF63380 172 277 9.32E-21 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CAK77_RS15580 835bc22c040738b51396af0d71ab3fb6 413 Pfam PF00175 Oxidoreductase NAD-binding domain 286 386 1.8E-10 T 06-07-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CAK77_RS15580 835bc22c040738b51396af0d71ab3fb6 413 SUPERFAMILY SSF52343 278 407 1.83E-28 T 06-07-2017 CAK77_RS15580 835bc22c040738b51396af0d71ab3fb6 413 Gene3D G3DSA:1.10.490.10 20 162 2.4E-41 T 06-07-2017 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 CAK77_RS23725 786f3f6a168021065feb22424beb9695 123 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 20 113 16.771 T 06-07-2017 IPR003482 Transcription factor WhiB CAK77_RS23725 786f3f6a168021065feb22424beb9695 123 Pfam PF02467 Transcription factor WhiB 37 105 1.6E-19 T 06-07-2017 IPR003482 Transcription factor WhiB CAK77_RS13625 923705f8ee442ff96ac2701709618b7e 278 Gene3D G3DSA:3.40.190.10 194 261 2.0E-4 T 06-07-2017 CAK77_RS13625 923705f8ee442ff96ac2701709618b7e 278 Gene3D G3DSA:3.40.190.10 59 181 2.5E-17 T 06-07-2017 CAK77_RS13625 923705f8ee442ff96ac2701709618b7e 278 Pfam PF13531 Bacterial extracellular solute-binding protein 60 275 7.3E-29 T 06-07-2017 CAK77_RS13625 923705f8ee442ff96ac2701709618b7e 278 SUPERFAMILY SSF53850 59 276 2.0E-31 T 06-07-2017 CAK77_RS03200 c617bb9cd4615603bdf0525cc2e9fa11 387 SUPERFAMILY SSF53901 9 234 1.45E-23 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS03200 c617bb9cd4615603bdf0525cc2e9fa11 387 PIRSF PIRSF000429 5 341 1.4E-20 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 CAK77_RS03200 c617bb9cd4615603bdf0525cc2e9fa11 387 Gene3D G3DSA:3.40.47.10 16 114 1.7E-14 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS03200 c617bb9cd4615603bdf0525cc2e9fa11 387 Gene3D G3DSA:3.40.47.10 204 231 1.7E-14 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS03200 c617bb9cd4615603bdf0525cc2e9fa11 387 SUPERFAMILY SSF53901 262 378 3.4E-13 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS07135 69c3c28fc81158a55017396e8f71eceb 225 SUPERFAMILY SSF46689 5 77 5.64E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS07135 69c3c28fc81158a55017396e8f71eceb 225 Gene3D G3DSA:1.10.357.10 2 189 9.0E-32 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS07135 69c3c28fc81158a55017396e8f71eceb 225 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 58 2.5E-12 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS07135 69c3c28fc81158a55017396e8f71eceb 225 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 9.6E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS07135 69c3c28fc81158a55017396e8f71eceb 225 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 9.6E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS05385 f9667c07902af03dc9ccc8eee64cf7b4 531 SUPERFAMILY SSF52096 232 512 7.82E-73 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS05385 f9667c07902af03dc9ccc8eee64cf7b4 531 SUPERFAMILY SSF52096 22 263 3.95E-64 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS05385 f9667c07902af03dc9ccc8eee64cf7b4 531 Gene3D G3DSA:3.90.226.10 28 265 2.3E-64 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS05385 f9667c07902af03dc9ccc8eee64cf7b4 531 Gene3D G3DSA:3.90.226.10 275 523 2.0E-74 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS05385 f9667c07902af03dc9ccc8eee64cf7b4 531 Pfam PF01039 Carboxyl transferase domain 48 520 1.6E-140 T 06-07-2017 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAK77_RS13420 2b28befedf4bf2750f3c01984298bd05 117 SUPERFAMILY SSF52833 5 103 2.16E-31 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK77_RS13420 2b28befedf4bf2750f3c01984298bd05 117 Gene3D G3DSA:3.40.30.10 5 102 2.2E-30 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK77_RS13420 2b28befedf4bf2750f3c01984298bd05 117 PRINTS PR00421 Thioredoxin family signature 29 38 2.7E-8 T 06-07-2017 CAK77_RS13420 2b28befedf4bf2750f3c01984298bd05 117 PRINTS PR00421 Thioredoxin family signature 68 79 2.7E-8 T 06-07-2017 CAK77_RS13420 2b28befedf4bf2750f3c01984298bd05 117 PRINTS PR00421 Thioredoxin family signature 21 29 2.7E-8 T 06-07-2017 CAK77_RS13420 2b28befedf4bf2750f3c01984298bd05 117 ProSitePatterns PS00194 Thioredoxin family active site. 22 40 - T 06-07-2017 IPR017937 Thioredoxin, conserved site GO:0045454 CAK77_RS13420 2b28befedf4bf2750f3c01984298bd05 117 PIRSF PIRSF000077 1 104 3.3E-27 T 06-07-2017 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 CAK77_RS13420 2b28befedf4bf2750f3c01984298bd05 117 TIGRFAM TIGR01068 thioredoxin: thioredoxin 7 102 6.8E-32 T 06-07-2017 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 CAK77_RS13420 2b28befedf4bf2750f3c01984298bd05 117 Pfam PF00085 Thioredoxin 6 101 4.5E-25 T 06-07-2017 IPR013766 Thioredoxin domain GO:0045454 CAK77_RS16815 20eeed0f930fbdf60ce3f41ac88455b8 325 Pfam PF08241 Methyltransferase domain 80 177 3.5E-24 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CAK77_RS16815 20eeed0f930fbdf60ce3f41ac88455b8 325 Gene3D G3DSA:3.40.50.150 34 177 4.2E-39 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS16815 20eeed0f930fbdf60ce3f41ac88455b8 325 Gene3D G3DSA:3.40.50.150 210 321 4.2E-39 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS16815 20eeed0f930fbdf60ce3f41ac88455b8 325 SUPERFAMILY SSF53335 235 323 1.33E-37 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS16815 20eeed0f930fbdf60ce3f41ac88455b8 325 SUPERFAMILY SSF53335 38 202 1.33E-37 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS20605 85589bdc5f906d2ac7372c0706aadb21 353 Gene3D G3DSA:3.90.25.10 214 347 9.1E-28 T 06-07-2017 CAK77_RS20605 85589bdc5f906d2ac7372c0706aadb21 353 Gene3D G3DSA:3.40.50.720 1 213 5.3E-37 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS20605 85589bdc5f906d2ac7372c0706aadb21 353 SUPERFAMILY SSF51735 163 346 2.16E-66 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS20605 85589bdc5f906d2ac7372c0706aadb21 353 SUPERFAMILY SSF51735 1 127 2.16E-66 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS20605 85589bdc5f906d2ac7372c0706aadb21 353 Pfam PF01370 NAD dependent epimerase/dehydratase family 1 276 1.8E-41 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 CAK77_RS16885 8f68df5aac0c38ec22cfabce7d6c3e7f 190 SUPERFAMILY SSF46689 4 82 6.16E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS16885 8f68df5aac0c38ec22cfabce7d6c3e7f 190 Gene3D G3DSA:1.10.357.10 5 187 1.3E-21 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS16885 8f68df5aac0c38ec22cfabce7d6c3e7f 190 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 57 4.3E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS14460 47c2583f57161012753f613feb3a017c 295 Pfam PF07732 Multicopper oxidase 56 159 1.4E-22 T 06-07-2017 IPR011707 Multicopper oxidase, type 3 GO:0005507 CAK77_RS14460 47c2583f57161012753f613feb3a017c 295 Gene3D G3DSA:2.60.40.420 38 166 2.2E-23 T 06-07-2017 IPR008972 Cupredoxin CAK77_RS14460 47c2583f57161012753f613feb3a017c 295 SUPERFAMILY SSF49503 38 161 2.28E-23 T 06-07-2017 IPR008972 Cupredoxin CAK77_RS14460 47c2583f57161012753f613feb3a017c 295 SUPERFAMILY SSF49503 214 286 2.55E-8 T 06-07-2017 IPR008972 Cupredoxin CAK77_RS14460 47c2583f57161012753f613feb3a017c 295 Gene3D G3DSA:2.60.40.420 215 273 1.4E-10 T 06-07-2017 IPR008972 Cupredoxin CAK77_RS01750 b1a94a3fd2cad6154ac886a5ca968cc1 404 Gene3D G3DSA:3.40.50.300 118 300 2.6E-51 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS01750 b1a94a3fd2cad6154ac886a5ca968cc1 404 SUPERFAMILY SSF48452 11 69 8.28E-5 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK77_RS01750 b1a94a3fd2cad6154ac886a5ca968cc1 404 Gene3D G3DSA:1.25.40.10 12 65 9.8E-5 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK77_RS01750 b1a94a3fd2cad6154ac886a5ca968cc1 404 SUPERFAMILY SSF52540 119 352 2.47E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS01750 b1a94a3fd2cad6154ac886a5ca968cc1 404 Gene3D G3DSA:1.10.8.60 301 370 2.2E-15 T 06-07-2017 CAK77_RS01750 b1a94a3fd2cad6154ac886a5ca968cc1 404 SMART SM00382 156 294 1.8E-20 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS01750 b1a94a3fd2cad6154ac886a5ca968cc1 404 ProSitePatterns PS00674 AAA-protein family signature. 262 280 - T 06-07-2017 IPR003960 ATPase, AAA-type, conserved site GO:0005524 CAK77_RS01750 b1a94a3fd2cad6154ac886a5ca968cc1 404 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 160 290 1.5E-37 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 CAK77_RS23295 2c28a489c333e4bc03d5a1d58be028cf 270 Gene3D G3DSA:3.40.50.1820 2 263 2.3E-30 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS23295 2c28a489c333e4bc03d5a1d58be028cf 270 Pfam PF12697 Alpha/beta hydrolase family 24 258 1.8E-13 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS23295 2c28a489c333e4bc03d5a1d58be028cf 270 SUPERFAMILY SSF53474 2 264 1.14E-32 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS23460 d4fe6b3d43c4798a4eda83cc7b2d7ece 135 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 13 125 8.1E-8 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CAK77_RS23460 d4fe6b3d43c4798a4eda83cc7b2d7ece 135 SUPERFAMILY SSF54593 10 127 3.03E-19 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK77_RS23460 d4fe6b3d43c4798a4eda83cc7b2d7ece 135 Gene3D G3DSA:3.10.180.10 7 128 5.8E-27 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK77_RS02885 d5cdc4b041fa35a653165d307b628916 479 Pfam PF04185 Phosphoesterase family 47 404 6.6E-110 T 06-07-2017 IPR007312 Phosphoesterase GO:0016788 CAK77_RS09825 e544af9bf37aa18016f96c9958e37d3b 324 SUPERFAMILY SSF56281 9 274 2.66E-47 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK77_RS09825 e544af9bf37aa18016f96c9958e37d3b 324 Gene3D G3DSA:3.60.15.10 144 256 5.5E-43 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK77_RS09825 e544af9bf37aa18016f96c9958e37d3b 324 Gene3D G3DSA:3.60.15.10 11 109 5.5E-43 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK77_RS09825 e544af9bf37aa18016f96c9958e37d3b 324 Pfam PF00753 Metallo-beta-lactamase superfamily 27 229 1.0E-19 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK77_RS09825 e544af9bf37aa18016f96c9958e37d3b 324 SMART SM00849 30 229 7.8E-20 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK77_RS09855 db072c40421cb83b9543a7be10575390 446 SUPERFAMILY SSF53901 246 445 3.95E-69 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS09855 db072c40421cb83b9543a7be10575390 446 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 28 277 1.3E-34 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAK77_RS09855 db072c40421cb83b9543a7be10575390 446 SUPERFAMILY SSF53901 28 282 2.97E-48 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS09855 db072c40421cb83b9543a7be10575390 446 Gene3D G3DSA:3.40.47.10 294 445 8.7E-59 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS09855 db072c40421cb83b9543a7be10575390 446 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 285 401 1.1E-37 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAK77_RS09855 db072c40421cb83b9543a7be10575390 446 Gene3D G3DSA:3.40.47.10 30 290 1.4E-45 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS09855 db072c40421cb83b9543a7be10575390 446 SMART SM00825 Beta-ketoacyl synthase 36 446 1.0E-18 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAK77_RS03220 4953cfdb8d9ff337aa8e02c9db95898f 559 Gene3D G3DSA:3.50.50.60 203 315 7.0E-66 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS03220 4953cfdb8d9ff337aa8e02c9db95898f 559 Gene3D G3DSA:3.50.50.60 497 558 7.0E-66 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS03220 4953cfdb8d9ff337aa8e02c9db95898f 559 Gene3D G3DSA:3.50.50.60 2 139 7.0E-66 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS03220 4953cfdb8d9ff337aa8e02c9db95898f 559 Gene3D G3DSA:3.90.700.10 326 493 2.6E-38 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK77_RS03220 4953cfdb8d9ff337aa8e02c9db95898f 559 Pfam PF00890 FAD binding domain 7 541 3.3E-90 T 06-07-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK77_RS03220 4953cfdb8d9ff337aa8e02c9db95898f 559 SUPERFAMILY SSF56425 317 495 2.88E-36 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK77_RS03220 4953cfdb8d9ff337aa8e02c9db95898f 559 SUPERFAMILY SSF51905 212 321 4.72E-42 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS03220 4953cfdb8d9ff337aa8e02c9db95898f 559 SUPERFAMILY SSF51905 3 129 4.72E-42 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS03220 4953cfdb8d9ff337aa8e02c9db95898f 559 SUPERFAMILY SSF51905 500 558 4.72E-42 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS03105 20297a71f4381933a7ddcad96395257c 218 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 48 71 4.2E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS03105 20297a71f4381933a7ddcad96395257c 218 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 40 4.2E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS03105 20297a71f4381933a7ddcad96395257c 218 SUPERFAMILY SSF46689 19 98 5.99E-20 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS03105 20297a71f4381933a7ddcad96395257c 218 Gene3D G3DSA:1.10.357.10 73 208 2.8E-41 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS03105 20297a71f4381933a7ddcad96395257c 218 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 73 2.9E-18 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS03105 20297a71f4381933a7ddcad96395257c 218 Gene3D G3DSA:1.10.10.60 18 72 2.2E-21 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS03105 20297a71f4381933a7ddcad96395257c 218 SUPERFAMILY SSF48498 94 207 6.68E-20 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS12345 2c82258b721a5723f4c332e5fc2f04a5 327 SUPERFAMILY SSF56317 27 311 5.1E-63 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAK77_RS12345 2c82258b721a5723f4c332e5fc2f04a5 327 Pfam PF00795 Carbon-nitrogen hydrolase 30 294 5.1E-46 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAK77_RS12345 2c82258b721a5723f4c332e5fc2f04a5 327 Gene3D G3DSA:3.60.110.10 28 312 5.4E-68 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAK77_RS16735 8adde8d679c7a4c7cfe969414910464c 517 SUPERFAMILY SSF88713 7 399 1.11E-92 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CAK77_RS16735 8adde8d679c7a4c7cfe969414910464c 517 SUPERFAMILY SSF88688 394 516 9.16E-23 T 06-07-2017 IPR028995 Glycoside hydrolase families 57/38, central domain CAK77_RS16735 8adde8d679c7a4c7cfe969414910464c 517 Pfam PF09210 Domain of unknown function (DUF1957) 422 513 1.6E-21 T 06-07-2017 IPR015293 Domain of unknown function DUF1957 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 CAK77_RS16735 8adde8d679c7a4c7cfe969414910464c 517 Pfam PF03065 Glycosyl hydrolase family 57 11 274 1.3E-20 T 06-07-2017 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 CAK77_RS16735 8adde8d679c7a4c7cfe969414910464c 517 Gene3D G3DSA:3.20.110.10 6 399 2.9E-116 T 06-07-2017 IPR027291 Glycoside hydrolase 38/57, N-terminal domain CAK77_RS16735 8adde8d679c7a4c7cfe969414910464c 517 Gene3D G3DSA:1.20.1430.10 418 512 7.0E-13 T 06-07-2017 IPR015293 Domain of unknown function DUF1957 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 CAK77_RS01680 ecdc483107a9b472780e0660fda63e6d 101 Hamap MF_00537 30S ribosomal protein S14 [rpsN]. 1 101 26.258 T 06-07-2017 IPR023036 Ribosomal protein S14, bacterial/plastid CAK77_RS01680 ecdc483107a9b472780e0660fda63e6d 101 Gene3D G3DSA:4.10.830.10 41 101 6.8E-27 T 06-07-2017 CAK77_RS01680 ecdc483107a9b472780e0660fda63e6d 101 SUPERFAMILY SSF57716 2 101 1.62E-33 T 06-07-2017 CAK77_RS01680 ecdc483107a9b472780e0660fda63e6d 101 Pfam PF00253 Ribosomal protein S14p/S29e 48 100 4.6E-23 T 06-07-2017 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS15345 0f3defd41053b5a045b01f6cb560024c 289 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 9 268 8.7E-65 T 06-07-2017 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 CAK77_RS15345 0f3defd41053b5a045b01f6cb560024c 289 Pfam PF04072 Leucine carboxyl methyltransferase 12 192 1.8E-39 T 06-07-2017 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 CAK77_RS15345 0f3defd41053b5a045b01f6cb560024c 289 SUPERFAMILY SSF53335 9 288 5.54E-55 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS15345 0f3defd41053b5a045b01f6cb560024c 289 Gene3D G3DSA:3.40.50.150 81 202 9.0E-16 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS21100 36b7deea78e0a7db5ff83cdd11c66b1a 238 ProSitePatterns PS00893 Nudix box signature. 101 122 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CAK77_RS21100 36b7deea78e0a7db5ff83cdd11c66b1a 238 Gene3D G3DSA:3.90.79.10 73 214 6.0E-30 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAK77_RS21100 36b7deea78e0a7db5ff83cdd11c66b1a 238 Gene3D G3DSA:3.90.79.10 12 39 6.0E-30 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAK77_RS21100 36b7deea78e0a7db5ff83cdd11c66b1a 238 SUPERFAMILY SSF55811 71 182 5.01E-25 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAK77_RS21100 36b7deea78e0a7db5ff83cdd11c66b1a 238 Pfam PF00293 NUDIX domain 77 176 1.8E-14 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 CAK77_RS21100 36b7deea78e0a7db5ff83cdd11c66b1a 238 PRINTS PR00502 NUDIX hydrolase family signature 96 110 3.9E-6 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CAK77_RS21100 36b7deea78e0a7db5ff83cdd11c66b1a 238 PRINTS PR00502 NUDIX hydrolase family signature 110 125 3.9E-6 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CAK77_RS04460 85e9062adda0e2ade25cd07e007e65a7 143 Pfam PF01047 MarR family 33 90 1.2E-14 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK77_RS04460 85e9062adda0e2ade25cd07e007e65a7 143 SUPERFAMILY SSF46785 5 138 1.39E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS04460 85e9062adda0e2ade25cd07e007e65a7 143 Gene3D G3DSA:1.10.10.10 3 135 5.5E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS04460 85e9062adda0e2ade25cd07e007e65a7 143 ProSitePatterns PS01117 MarR-type HTH domain signature. 64 98 - T 06-07-2017 IPR023187 Transcriptional regulator MarR-type, conserved site CAK77_RS04460 85e9062adda0e2ade25cd07e007e65a7 143 SMART SM00347 25 125 7.5E-23 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK77_RS09210 3dac87cde26cb9ca913f3256cf50f24f 379 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 3 355 1.6E-43 T 06-07-2017 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 CAK77_RS09210 3dac87cde26cb9ca913f3256cf50f24f 379 PIRSF PIRSF037489 2 371 4.3E-137 T 06-07-2017 IPR017221 GTP cyclohydrolase 1 type 2//Nif3, bacteria CAK77_RS09210 3dac87cde26cb9ca913f3256cf50f24f 379 Gene3D G3DSA:3.30.70.830 133 234 3.7E-38 T 06-07-2017 CAK77_RS09210 3dac87cde26cb9ca913f3256cf50f24f 379 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 7 352 1.3E-65 T 06-07-2017 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 CAK77_RS09210 3dac87cde26cb9ca913f3256cf50f24f 379 SUPERFAMILY SSF102705 4 369 2.09E-109 T 06-07-2017 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 CAK77_RS09210 3dac87cde26cb9ca913f3256cf50f24f 379 Gene3D G3DSA:3.40.1390.30 4 115 1.2E-38 T 06-07-2017 CAK77_RS09210 3dac87cde26cb9ca913f3256cf50f24f 379 Gene3D G3DSA:3.40.1390.30 238 328 6.6E-34 T 06-07-2017 CAK77_RS09210 3dac87cde26cb9ca913f3256cf50f24f 379 Gene3D G3DSA:3.40.1390.30 116 131 6.6E-34 T 06-07-2017 CAK77_RS12915 3f2797e2f415c4d6d91a1e26d92896ee 394 Gene3D G3DSA:3.40.50.2300 94 189 3.0E-6 T 06-07-2017 CAK77_RS12915 3f2797e2f415c4d6d91a1e26d92896ee 394 SUPERFAMILY SSF53822 72 393 8.07E-62 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAK77_RS12915 3f2797e2f415c4d6d91a1e26d92896ee 394 Pfam PF13458 Periplasmic binding protein 72 393 1.4E-35 T 06-07-2017 IPR028081 Leucine-binding protein domain CAK77_RS12915 3f2797e2f415c4d6d91a1e26d92896ee 394 Gene3D G3DSA:3.40.50.2300 190 347 1.2E-37 T 06-07-2017 CAK77_RS14945 c8527a807e70cb0c7b59715d911e6943 245 Pfam PF12502 Protein of unknown function (DUF3710) 25 194 1.3E-53 T 06-07-2017 IPR022183 Protein of unknown function DUF3710 CAK77_RS10635 cf4dae28dd9ecfd4d1a5607be04f1f5d 295 SUPERFAMILY SSF52980 175 265 1.13E-7 T 06-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CAK77_RS07600 b0c844dd70ad05f6498d9ed080fb4d3d 273 PRINTS PR00111 Alpha/beta hydrolase fold signature 102 115 3.5E-5 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS07600 b0c844dd70ad05f6498d9ed080fb4d3d 273 PRINTS PR00111 Alpha/beta hydrolase fold signature 88 101 3.5E-5 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS07600 b0c844dd70ad05f6498d9ed080fb4d3d 273 PRINTS PR00111 Alpha/beta hydrolase fold signature 44 59 3.5E-5 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS07600 b0c844dd70ad05f6498d9ed080fb4d3d 273 SUPERFAMILY SSF53474 3 268 7.7E-38 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS07600 b0c844dd70ad05f6498d9ed080fb4d3d 273 Pfam PF12697 Alpha/beta hydrolase family 21 265 6.4E-19 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS07600 b0c844dd70ad05f6498d9ed080fb4d3d 273 Gene3D G3DSA:3.40.50.1820 1 268 1.5E-39 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS07355 641ee57ae3e480f6fbcb57ecddf5cf9f 157 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 22 137 7.0E-20 T 06-07-2017 CAK77_RS07355 641ee57ae3e480f6fbcb57ecddf5cf9f 157 TIGRFAM TIGR03081 metmalonyl_epim: methylmalonyl-CoA epimerase 21 152 1.2E-38 T 06-07-2017 IPR017515 Methylmalonyl-CoA epimerase KEGG: 00280+5.1.99.1|KEGG: 00630+5.1.99.1|KEGG: 00640+5.1.99.1|KEGG: 00720+5.1.99.1|MetaCyc: PWY-5741|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384|Reactome: R-HSA-71032 CAK77_RS07355 641ee57ae3e480f6fbcb57ecddf5cf9f 157 Gene3D G3DSA:3.10.180.10 19 152 3.3E-37 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK77_RS07355 641ee57ae3e480f6fbcb57ecddf5cf9f 157 SUPERFAMILY SSF54593 18 155 3.85E-35 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK77_RS14365 578f35630bee395ea2a429ac983a6d71 213 SUPERFAMILY SSF46689 13 84 5.23E-6 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS14365 578f35630bee395ea2a429ac983a6d71 213 Gene3D G3DSA:1.10.357.10 16 182 2.1E-10 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS03715 1abc7207cc0d5b86a59a378510789ea2 341 Gene3D G3DSA:1.10.3720.10 207 335 7.7E-16 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS03715 1abc7207cc0d5b86a59a378510789ea2 341 Gene3D G3DSA:1.10.3720.10 100 165 7.7E-16 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS03715 1abc7207cc0d5b86a59a378510789ea2 341 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 340 1.7E-38 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS03715 1abc7207cc0d5b86a59a378510789ea2 341 SUPERFAMILY SSF161098 99 162 1.18E-12 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS03715 1abc7207cc0d5b86a59a378510789ea2 341 SUPERFAMILY SSF161098 204 325 1.18E-12 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS10680 6bddd1dfc0a6da0cc632a4aeda6aa437 141 Gene3D G3DSA:2.30.110.10 9 128 2.0E-30 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS10680 6bddd1dfc0a6da0cc632a4aeda6aa437 141 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 9 94 3.8E-13 T 06-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAK77_RS10680 6bddd1dfc0a6da0cc632a4aeda6aa437 141 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 14 128 9.0E-29 T 06-07-2017 IPR019920 F420-binding domain, putative CAK77_RS10680 6bddd1dfc0a6da0cc632a4aeda6aa437 141 SUPERFAMILY SSF50475 10 128 1.25E-33 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS20375 3e9b1fc137589d987c8fa1e4f389e437 167 Pfam PF10698 Protein of unknown function (DUF2505) 7 163 1.5E-52 T 06-07-2017 IPR019639 Protein of unknown function DUF2505 CAK77_RS00520 a4c642a4a0a455a8e20368819f8a95f6 264 Gene3D G3DSA:3.40.50.720 2 261 2.5E-73 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS00520 a4c642a4a0a455a8e20368819f8a95f6 264 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK77_RS00520 a4c642a4a0a455a8e20368819f8a95f6 264 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 261 1.5E-53 T 06-07-2017 CAK77_RS00520 a4c642a4a0a455a8e20368819f8a95f6 264 TIGRFAM TIGR03971 SDR_subfam_1: SDR family mycofactocin-dependent oxidoreductase 4 262 4.4E-96 T 06-07-2017 IPR023985 Mycofactocin-dependent oxidoreductase CAK77_RS00520 a4c642a4a0a455a8e20368819f8a95f6 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 1.1E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS00520 a4c642a4a0a455a8e20368819f8a95f6 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 1.1E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS00520 a4c642a4a0a455a8e20368819f8a95f6 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 1.1E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS00520 a4c642a4a0a455a8e20368819f8a95f6 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 1.2E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS00520 a4c642a4a0a455a8e20368819f8a95f6 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 224 244 1.2E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS00520 a4c642a4a0a455a8e20368819f8a95f6 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.2E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS00520 a4c642a4a0a455a8e20368819f8a95f6 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 1.2E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS00520 a4c642a4a0a455a8e20368819f8a95f6 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 1.2E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS00520 a4c642a4a0a455a8e20368819f8a95f6 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 1.2E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS00520 a4c642a4a0a455a8e20368819f8a95f6 264 SUPERFAMILY SSF51735 6 261 5.0E-70 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS00585 e43aca8497fb6807adaf1c6b2297a56b 310 Gene3D G3DSA:3.60.130.10 3 290 4.8E-83 T 06-07-2017 CAK77_RS00585 e43aca8497fb6807adaf1c6b2297a56b 310 SUPERFAMILY SSF51197 5 286 1.47E-76 T 06-07-2017 CAK77_RS00585 e43aca8497fb6807adaf1c6b2297a56b 310 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 9 275 1.1E-51 T 06-07-2017 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 CAK77_RS21265 d4d9268ab70275c78eb38447e174c8fa 141 SMART SM00450 8 125 1.8E-9 T 06-07-2017 IPR001763 Rhodanese-like domain CAK77_RS21265 d4d9268ab70275c78eb38447e174c8fa 141 Pfam PF00581 Rhodanese-like domain 9 117 3.6E-5 T 06-07-2017 IPR001763 Rhodanese-like domain CAK77_RS21265 d4d9268ab70275c78eb38447e174c8fa 141 Gene3D G3DSA:3.40.250.10 2 140 1.1E-41 T 06-07-2017 IPR001763 Rhodanese-like domain CAK77_RS21265 d4d9268ab70275c78eb38447e174c8fa 141 SUPERFAMILY SSF52821 6 139 1.96E-18 T 06-07-2017 IPR001763 Rhodanese-like domain CAK77_RS16190 deb82fa1b46a9a47636a5aff771af4ed 572 Pfam PF03814 Potassium-transporting ATPase A subunit 14 570 4.1E-219 T 06-07-2017 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 CAK77_RS16190 deb82fa1b46a9a47636a5aff771af4ed 572 TIGRFAM TIGR00680 kdpA: K+-transporting ATPase, A subunit 9 570 2.5E-196 T 06-07-2017 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 CAK77_RS16190 deb82fa1b46a9a47636a5aff771af4ed 572 PIRSF PIRSF001294 4 572 2.5E-205 T 06-07-2017 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 CAK77_RS16190 deb82fa1b46a9a47636a5aff771af4ed 572 Hamap MF_00275 Potassium-transporting ATPase potassium-binding subunit [kdpA]. 4 572 32.074 T 06-07-2017 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 CAK77_RS04355 d2bb75c43c78243c114d24558f492ad5 161 Gene3D G3DSA:3.30.530.20 19 155 1.5E-4 T 06-07-2017 IPR023393 START-like domain CAK77_RS04355 d2bb75c43c78243c114d24558f492ad5 161 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 17 151 2.0E-10 T 06-07-2017 IPR019587 Polyketide cyclase/dehydrase CAK77_RS04355 d2bb75c43c78243c114d24558f492ad5 161 SUPERFAMILY SSF55961 17 131 6.93E-9 T 06-07-2017 CAK77_RS06570 7dcb85e2a680c0a7f52de07f53e7b2c4 126 Gene3D G3DSA:3.10.180.10 4 120 1.9E-11 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK77_RS06570 7dcb85e2a680c0a7f52de07f53e7b2c4 126 SUPERFAMILY SSF54593 1 120 1.41E-16 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK77_RS03150 cede1f1bba3a58b90070c4965fd06c8a 303 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 160 8.2E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS03150 cede1f1bba3a58b90070c4965fd06c8a 303 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 8.2E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS03150 cede1f1bba3a58b90070c4965fd06c8a 303 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 189 8.2E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS03150 cede1f1bba3a58b90070c4965fd06c8a 303 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 91 102 8.2E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS03150 cede1f1bba3a58b90070c4965fd06c8a 303 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 191 208 8.2E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS03150 cede1f1bba3a58b90070c4965fd06c8a 303 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 221 241 8.2E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS03150 cede1f1bba3a58b90070c4965fd06c8a 303 Gene3D G3DSA:3.40.50.720 1 262 1.4E-69 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS03150 cede1f1bba3a58b90070c4965fd06c8a 303 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 170 189 3.6E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS03150 cede1f1bba3a58b90070c4965fd06c8a 303 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 158 3.6E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS03150 cede1f1bba3a58b90070c4965fd06c8a 303 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 91 102 3.6E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS03150 cede1f1bba3a58b90070c4965fd06c8a 303 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 201 1.3E-5 T 06-07-2017 CAK77_RS03150 cede1f1bba3a58b90070c4965fd06c8a 303 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 157 185 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK77_RS03150 cede1f1bba3a58b90070c4965fd06c8a 303 SUPERFAMILY SSF51735 5 259 1.72E-61 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS03150 cede1f1bba3a58b90070c4965fd06c8a 303 Pfam PF00106 short chain dehydrogenase 9 210 2.3E-43 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS05855 a3c065ed34b32a915ebf2437bc6bf45b 215 Gene3D G3DSA:3.40.50.1390 8 134 2.4E-17 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CAK77_RS05855 a3c065ed34b32a915ebf2437bc6bf45b 215 ProSitePatterns PS00397 Site-specific recombinases active site. 12 20 - T 06-07-2017 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 CAK77_RS05855 a3c065ed34b32a915ebf2437bc6bf45b 215 SMART SM00857 9 155 1.9E-28 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CAK77_RS05855 a3c065ed34b32a915ebf2437bc6bf45b 215 Gene3D G3DSA:1.20.5.40 135 154 8.1E-7 T 06-07-2017 CAK77_RS05855 a3c065ed34b32a915ebf2437bc6bf45b 215 Pfam PF07508 Recombinase 163 212 1.9E-7 T 06-07-2017 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 CAK77_RS05855 a3c065ed34b32a915ebf2437bc6bf45b 215 Pfam PF00239 Resolvase, N terminal domain 9 154 2.2E-24 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CAK77_RS05855 a3c065ed34b32a915ebf2437bc6bf45b 215 SUPERFAMILY SSF53041 8 154 1.7E-22 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CAK77_RS14310 5dda521f190168a39464909e95aa15d0 665 SUPERFAMILY SSF53271 1 207 1.36E-51 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like CAK77_RS14310 5dda521f190168a39464909e95aa15d0 665 Gene3D G3DSA:3.40.50.2020 2 61 7.7E-39 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like CAK77_RS14310 5dda521f190168a39464909e95aa15d0 665 Gene3D G3DSA:3.40.50.2020 97 202 7.7E-39 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like CAK77_RS14310 5dda521f190168a39464909e95aa15d0 665 Gene3D G3DSA:3.30.1870.10 279 361 3.1E-26 T 06-07-2017 CAK77_RS14310 5dda521f190168a39464909e95aa15d0 665 Pfam PF05139 Erythromycin esterase 277 640 3.4E-108 T 06-07-2017 IPR007815 Erythromycin esterase GO:0046677 CAK77_RS14310 5dda521f190168a39464909e95aa15d0 665 SUPERFAMILY SSF159501 226 646 4.53E-122 T 06-07-2017 CAK77_RS14310 5dda521f190168a39464909e95aa15d0 665 Pfam PF00156 Phosphoribosyl transferase domain 7 187 1.5E-23 T 06-07-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 CAK77_RS14310 5dda521f190168a39464909e95aa15d0 665 Gene3D G3DSA:3.40.1660.10 503 646 7.0E-69 T 06-07-2017 CAK77_RS14310 5dda521f190168a39464909e95aa15d0 665 Gene3D G3DSA:3.40.1660.10 226 278 7.0E-69 T 06-07-2017 CAK77_RS23760 92f5d10f29673ae12c642731d0fa8719 147 Gene3D G3DSA:2.60.120.10 39 117 9.9E-4 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK77_RS23760 92f5d10f29673ae12c642731d0fa8719 147 Pfam PF05423 Mycobacterium membrane protein 12 147 4.0E-30 T 06-07-2017 IPR008693 Transport accessory protein MmpS CAK77_RS18565 15ddc9696ada82cde809690f0099d7e9 167 Pfam PF07508 Recombinase 65 160 1.6E-10 T 06-07-2017 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 CAK77_RS20290 dd1e784a62023bfdcd66c138bea0c2c9 524 SUPERFAMILY SSF51905 19 237 5.65E-49 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS20290 dd1e784a62023bfdcd66c138bea0c2c9 524 SUPERFAMILY SSF51905 309 431 5.65E-49 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS20290 dd1e784a62023bfdcd66c138bea0c2c9 524 PRINTS PR00419 Adrenodoxin reductase family signature 18 40 2.9E-6 T 06-07-2017 CAK77_RS20290 dd1e784a62023bfdcd66c138bea0c2c9 524 PRINTS PR00419 Adrenodoxin reductase family signature 42 55 2.9E-6 T 06-07-2017 CAK77_RS20290 dd1e784a62023bfdcd66c138bea0c2c9 524 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 20 216 2.6E-13 T 06-07-2017 CAK77_RS20290 dd1e784a62023bfdcd66c138bea0c2c9 524 Gene3D G3DSA:3.50.50.60 10 220 7.9E-53 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS20290 dd1e784a62023bfdcd66c138bea0c2c9 524 Gene3D G3DSA:3.50.50.60 284 482 1.2E-9 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS19665 d73c49b75427bb3e08a600e4e4e6b54a 199 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 30 138 9.5E-9 T 06-07-2017 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 CAK77_RS19665 d73c49b75427bb3e08a600e4e4e6b54a 199 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 29 197 1.5E-22 T 06-07-2017 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type CAK77_RS19665 d73c49b75427bb3e08a600e4e4e6b54a 199 Gene3D G3DSA:1.20.120.450 26 77 3.6E-7 T 06-07-2017 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase CAK77_RS19665 d73c49b75427bb3e08a600e4e4e6b54a 199 TIGRFAM TIGR03086 TIGR03086: TIGR03086 family protein 30 197 2.1E-35 T 06-07-2017 IPR017520 Conserved hypothetical protein CHP03086 CAK77_RS19665 d73c49b75427bb3e08a600e4e4e6b54a 199 SUPERFAMILY SSF109854 26 145 1.98E-16 T 06-07-2017 CAK77_RS19055 1c643a5531a209a7bd32a4ede5ea68df 100 Gene3D G3DSA:3.30.70.330 6 96 1.7E-35 T 06-07-2017 IPR012677 Nucleotide-binding alpha-beta plait domain GO:0000166 CAK77_RS19055 1c643a5531a209a7bd32a4ede5ea68df 100 Pfam PF00276 Ribosomal protein L23 9 91 3.2E-32 T 06-07-2017 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 CAK77_RS19055 1c643a5531a209a7bd32a4ede5ea68df 100 SUPERFAMILY SSF54189 5 95 1.65E-32 T 06-07-2017 IPR012678 Ribosomal protein L23/L15e core domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS19055 1c643a5531a209a7bd32a4ede5ea68df 100 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 8 98 21.784 T 06-07-2017 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 CAK77_RS19055 1c643a5531a209a7bd32a4ede5ea68df 100 ProSitePatterns PS00050 Ribosomal protein L23 signature. 80 95 - T 06-07-2017 IPR001014 Ribosomal protein L23/L25, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK77_RS23230 89d1bfec978c357b9f0f6cf24e8eccb4 245 PIRSF PIRSF033303 3 225 2.5E-51 T 06-07-2017 IPR014581 Uncharacterised conserved protein UCP033303 CAK77_RS23230 89d1bfec978c357b9f0f6cf24e8eccb4 245 Pfam PF07040 Protein of unknown function (DUF1326) 26 208 3.8E-58 T 06-07-2017 IPR009758 Protein of unknown function DUF1326 CAK77_RS19125 2498561308937cd5bcceeff51ce92c0f 248 Gene3D G3DSA:3.40.50.10310 28 239 5.8E-56 T 06-07-2017 IPR024087 Creatininase-like domain KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167 CAK77_RS19125 2498561308937cd5bcceeff51ce92c0f 248 Pfam PF02633 Creatinine amidohydrolase 25 236 1.8E-53 T 06-07-2017 IPR003785 Creatininase/formamide hydrolase KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167 CAK77_RS19125 2498561308937cd5bcceeff51ce92c0f 248 TIGRFAM TIGR03964 mycofact_creat: mycofactocin system creatininase family protein 15 247 1.6E-108 T 06-07-2017 IPR023871 Mycofactocin system creatininase family protein CAK77_RS19125 2498561308937cd5bcceeff51ce92c0f 248 SUPERFAMILY SSF102215 21 239 1.27E-52 T 06-07-2017 IPR024087 Creatininase-like domain KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167 CAK77_RS17855 679ef7eecafafa781ad98d9893df6235 509 Gene3D G3DSA:3.40.50.980 182 323 1.5E-34 T 06-07-2017 CAK77_RS17855 679ef7eecafafa781ad98d9893df6235 509 Pfam PF13193 AMP-binding enzyme C-terminal domain 420 496 2.7E-25 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAK77_RS17855 679ef7eecafafa781ad98d9893df6235 509 Gene3D G3DSA:3.30.300.30 406 506 2.2E-32 T 06-07-2017 CAK77_RS17855 679ef7eecafafa781ad98d9893df6235 509 SUPERFAMILY SSF56801 6 507 8.37E-131 T 06-07-2017 CAK77_RS17855 679ef7eecafafa781ad98d9893df6235 509 Gene3D G3DSA:2.30.38.10 349 405 3.0E-13 T 06-07-2017 CAK77_RS17855 679ef7eecafafa781ad98d9893df6235 509 ProSitePatterns PS00455 Putative AMP-binding domain signature. 166 177 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK77_RS17855 679ef7eecafafa781ad98d9893df6235 509 Pfam PF00501 AMP-binding enzyme 19 411 4.8E-84 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK77_RS17855 679ef7eecafafa781ad98d9893df6235 509 Gene3D G3DSA:3.40.50.980 9 181 1.2E-31 T 06-07-2017 CAK77_RS18980 b85364bbade0e34fb4bc350b59901bef 506 Pfam PF00135 Carboxylesterase family 26 477 1.2E-110 T 06-07-2017 IPR002018 Carboxylesterase, type B CAK77_RS18980 b85364bbade0e34fb4bc350b59901bef 506 SUPERFAMILY SSF53474 25 480 6.91E-112 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS18980 b85364bbade0e34fb4bc350b59901bef 506 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 190 205 - T 06-07-2017 IPR019826 Carboxylesterase type B, active site CAK77_RS18980 b85364bbade0e34fb4bc350b59901bef 506 Gene3D G3DSA:3.40.50.1820 19 505 8.8E-133 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS15005 3c858ae2a0ff5530a42526a1edc355d1 458 SUPERFAMILY SSF51905 2 333 1.99E-54 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS15005 3c858ae2a0ff5530a42526a1edc355d1 458 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 311 1.9E-56 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS15005 3c858ae2a0ff5530a42526a1edc355d1 458 PIRSF PIRSF000350 1 450 1.8E-74 T 06-07-2017 CAK77_RS15005 3c858ae2a0ff5530a42526a1edc355d1 458 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 4.8E-24 T 06-07-2017 CAK77_RS15005 3c858ae2a0ff5530a42526a1edc355d1 458 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 171 189 4.8E-24 T 06-07-2017 CAK77_RS15005 3c858ae2a0ff5530a42526a1edc355d1 458 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 258 274 4.8E-24 T 06-07-2017 CAK77_RS15005 3c858ae2a0ff5530a42526a1edc355d1 458 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 287 309 4.8E-24 T 06-07-2017 CAK77_RS15005 3c858ae2a0ff5530a42526a1edc355d1 458 Gene3D G3DSA:3.30.390.30 329 450 1.5E-31 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CAK77_RS15005 3c858ae2a0ff5530a42526a1edc355d1 458 SUPERFAMILY SSF55424 344 451 1.46E-30 T 06-07-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CAK77_RS15005 3c858ae2a0ff5530a42526a1edc355d1 458 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 345 447 2.9E-23 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CAK77_RS15005 3c858ae2a0ff5530a42526a1edc355d1 458 Gene3D G3DSA:3.50.50.60 141 328 3.2E-49 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS15005 3c858ae2a0ff5530a42526a1edc355d1 458 Gene3D G3DSA:3.50.50.60 4 140 2.0E-30 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS15005 3c858ae2a0ff5530a42526a1edc355d1 458 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 259 273 7.6E-49 T 06-07-2017 CAK77_RS15005 3c858ae2a0ff5530a42526a1edc355d1 458 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 425 445 7.6E-49 T 06-07-2017 CAK77_RS15005 3c858ae2a0ff5530a42526a1edc355d1 458 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 171 196 7.6E-49 T 06-07-2017 CAK77_RS15005 3c858ae2a0ff5530a42526a1edc355d1 458 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 338 359 7.6E-49 T 06-07-2017 CAK77_RS15005 3c858ae2a0ff5530a42526a1edc355d1 458 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 302 309 7.6E-49 T 06-07-2017 CAK77_RS15005 3c858ae2a0ff5530a42526a1edc355d1 458 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 7.6E-49 T 06-07-2017 CAK77_RS15005 3c858ae2a0ff5530a42526a1edc355d1 458 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 403 418 7.6E-49 T 06-07-2017 CAK77_RS15005 3c858ae2a0ff5530a42526a1edc355d1 458 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 7.6E-49 T 06-07-2017 CAK77_RS16645 1172f54b1d26ee4ba0520859f1e9619d 250 Gene3D G3DSA:2.40.10.10 33 92 9.5E-6 T 06-07-2017 CAK77_RS16645 1172f54b1d26ee4ba0520859f1e9619d 250 SUPERFAMILY SSF50494 33 213 2.75E-15 T 06-07-2017 IPR009003 Peptidase S1, PA clan CAK77_RS16645 1172f54b1d26ee4ba0520859f1e9619d 250 Gene3D G3DSA:2.40.10.10 132 215 2.9E-6 T 06-07-2017 CAK77_RS19335 3c0e81488284e088ca37ac493f82bd30 503 Pfam PF03055 Retinal pigment epithelial membrane protein 20 502 2.9E-102 T 06-07-2017 IPR004294 Carotenoid oxygenase GO:0016702|GO:0055114 CAK77_RS20545 4d223870194fd0c6f0fe7d0b3e6979e3 76 Gene3D G3DSA:3.90.820.10 11 70 2.3E-33 T 06-07-2017 CAK77_RS20545 4d223870194fd0c6f0fe7d0b3e6979e3 76 SUPERFAMILY SSF160582 3 70 3.14E-32 T 06-07-2017 CAK77_RS20545 4d223870194fd0c6f0fe7d0b3e6979e3 76 Pfam PF03621 MbtH-like protein 4 54 5.1E-30 T 06-07-2017 IPR005153 MbtH-like protein CAK77_RS20545 4d223870194fd0c6f0fe7d0b3e6979e3 76 SMART SM00923 4 54 2.0E-35 T 06-07-2017 IPR005153 MbtH-like protein CAK77_RS09555 19649000d8d7b5e31bfb2601e600a790 546 Pfam PF13631 Cytochrome b(N-terminal)/b6/petB 117 291 8.8E-61 T 06-07-2017 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 CAK77_RS09555 19649000d8d7b5e31bfb2601e600a790 546 SUPERFAMILY SSF81342 17 295 1.54E-59 T 06-07-2017 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 CAK77_RS09555 19649000d8d7b5e31bfb2601e600a790 546 Gene3D G3DSA:1.20.810.10 17 437 1.8E-80 T 06-07-2017 IPR027387 Cytochrome b/b6-like domain Reactome: R-HSA-611105 CAK77_RS18760 7ad9fc9f834cd01fa225d34720a26d1d 174 Pfam PF11706 CGNR zinc finger 127 169 6.1E-18 T 06-07-2017 IPR021005 Zinc finger, CGNR CAK77_RS18760 7ad9fc9f834cd01fa225d34720a26d1d 174 Gene3D G3DSA:1.10.3300.10 3 171 9.1E-40 T 06-07-2017 IPR023286 ABATE domain CAK77_RS18760 7ad9fc9f834cd01fa225d34720a26d1d 174 Pfam PF07336 Putative stress-induced transcription regulator 2 123 8.3E-12 T 06-07-2017 IPR010852 Putative stress-induced transcription regulator CAK77_RS18760 7ad9fc9f834cd01fa225d34720a26d1d 174 SUPERFAMILY SSF160904 3 169 8.11E-39 T 06-07-2017 CAK77_RS05550 67dbfa42c5ee144d987ed9950a14d8f8 200 Gene3D G3DSA:2.60.120.590 77 195 1.6E-15 T 06-07-2017 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like CAK77_RS05550 67dbfa42c5ee144d987ed9950a14d8f8 200 Pfam PF13532 2OG-Fe(II) oxygenase superfamily 107 192 4.2E-12 T 06-07-2017 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like CAK77_RS05550 67dbfa42c5ee144d987ed9950a14d8f8 200 SUPERFAMILY SSF51197 17 195 1.65E-42 T 06-07-2017 CAK77_RS23615 7c84b943a3704a28694d3a31587564eb 341 PIRSF PIRSF037390 2 340 5.6E-122 T 06-07-2017 IPR017192 Thiosulphate:quinone oxidoreductase, fused subunit DoxA/ DoxD CAK77_RS23615 7c84b943a3704a28694d3a31587564eb 341 Pfam PF07680 TQO small subunit DoxA 205 335 7.5E-41 T 06-07-2017 IPR011636 Thiosulphate:quinone oxidoreductase small subunit DoxA KEGG: 00920+1.8.5.2|MetaCyc: PWY-5303 CAK77_RS23615 7c84b943a3704a28694d3a31587564eb 341 Pfam PF04173 TQO small subunit DoxD 19 172 1.8E-50 T 06-07-2017 IPR007301 TQO small subunit DoxD KEGG: 00920+1.8.5.2|MetaCyc: PWY-5303 CAK77_RS01135 3da385b00c1343fa591d6b5201d94f0b 554 SUPERFAMILY SSF101473 361 552 6.15E-40 T 06-07-2017 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CAK77_RS01135 3da385b00c1343fa591d6b5201d94f0b 554 Pfam PF02733 Dak1 domain 20 330 5.8E-115 T 06-07-2017 IPR004006 DhaK domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CAK77_RS01135 3da385b00c1343fa591d6b5201d94f0b 554 SUPERFAMILY SSF82549 14 333 2.41E-104 T 06-07-2017 CAK77_RS01135 3da385b00c1343fa591d6b5201d94f0b 554 SMART SM01120 384 553 1.7E-43 T 06-07-2017 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CAK77_RS01135 3da385b00c1343fa591d6b5201d94f0b 554 Pfam PF02734 DAK2 domain 385 552 2.8E-37 T 06-07-2017 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CAK77_RS01135 3da385b00c1343fa591d6b5201d94f0b 554 Gene3D G3DSA:3.40.50.10440 15 185 4.4E-61 T 06-07-2017 CAK77_RS01135 3da385b00c1343fa591d6b5201d94f0b 554 Gene3D G3DSA:3.30.1180.20 189 334 2.7E-54 T 06-07-2017 CAK77_RS22355 20f1efa0210369760fd9461c2c38f2ff 277 SUPERFAMILY SSF51679 2 258 8.9E-65 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS22355 20f1efa0210369760fd9461c2c38f2ff 277 TIGRFAM TIGR03560 F420_Rv1855c: probable F420-dependent oxidoreductase, Rv1855c family 3 227 8.0E-90 T 06-07-2017 IPR019952 F420-dependent oxidoreductase-predicted, Rv1855c CAK77_RS22355 20f1efa0210369760fd9461c2c38f2ff 277 Gene3D G3DSA:3.20.20.30 6 239 1.3E-69 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS22355 20f1efa0210369760fd9461c2c38f2ff 277 Pfam PF00296 Luciferase-like monooxygenase 10 246 2.5E-51 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS03430 cad5ed3bbe3c23b805bb851e482f1960 74 Gene3D G3DSA:1.10.1200.10 3 65 4.7E-4 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS03430 cad5ed3bbe3c23b805bb851e482f1960 74 Pfam PF00550 Phosphopantetheine attachment site 2 55 3.9E-8 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS03430 cad5ed3bbe3c23b805bb851e482f1960 74 SUPERFAMILY SSF47336 4 66 5.37E-5 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS23740 4459bdec5157438a5de92310c17f179a 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 67 2.7E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS23740 4459bdec5157438a5de92310c17f179a 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 5.2E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS23740 4459bdec5157438a5de92310c17f179a 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 35 5.2E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS23740 4459bdec5157438a5de92310c17f179a 201 SUPERFAMILY SSF46689 13 93 7.48E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS23740 4459bdec5157438a5de92310c17f179a 201 Gene3D G3DSA:1.10.357.10 14 192 1.1E-20 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS00765 5780246043c2ac4bc5bf599e89f7aaed 248 Gene3D G3DSA:3.30.1060.10 27 225 8.3E-77 T 06-07-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CAK77_RS00765 5780246043c2ac4bc5bf599e89f7aaed 248 SUPERFAMILY SSF55068 27 235 9.03E-77 T 06-07-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CAK77_RS00765 5780246043c2ac4bc5bf599e89f7aaed 248 Pfam PF01625 Peptide methionine sulfoxide reductase 65 225 8.9E-64 T 06-07-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CAK77_RS00765 5780246043c2ac4bc5bf599e89f7aaed 248 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 64 225 6.0E-62 T 06-07-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CAK77_RS00765 5780246043c2ac4bc5bf599e89f7aaed 248 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 62 231 38.218 T 06-07-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CAK77_RS18430 f224c85f78ece4d08252595f7a657bc7 153 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 2 150 28.339 T 06-07-2017 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 CAK77_RS18430 f224c85f78ece4d08252595f7a657bc7 153 PIRSF PIRSF029256 1 152 1.7E-52 T 06-07-2017 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 CAK77_RS18430 f224c85f78ece4d08252595f7a657bc7 153 Gene3D G3DSA:3.40.1280.10 2 151 2.9E-54 T 06-07-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CAK77_RS18430 f224c85f78ece4d08252595f7a657bc7 153 SUPERFAMILY SSF75217 2 150 9.81E-38 T 06-07-2017 IPR029028 Alpha/beta knot methyltransferases CAK77_RS18430 f224c85f78ece4d08252595f7a657bc7 153 Pfam PF00588 SpoU rRNA Methylase family 2 141 4.7E-28 T 06-07-2017 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CAK77_RS07165 1127c7822ad2189b26c142c96fa4834b 199 SUPERFAMILY SSF48498 75 197 4.11E-25 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS07165 1127c7822ad2189b26c142c96fa4834b 199 Gene3D G3DSA:1.10.10.60 2 61 9.5E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS07165 1127c7822ad2189b26c142c96fa4834b 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 10 55 1.5E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS07165 1127c7822ad2189b26c142c96fa4834b 199 ProSitePatterns PS01081 TetR-type HTH domain signature. 21 52 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CAK77_RS07165 1127c7822ad2189b26c142c96fa4834b 199 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 75 197 3.6E-21 T 06-07-2017 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 CAK77_RS07165 1127c7822ad2189b26c142c96fa4834b 199 SUPERFAMILY SSF46689 4 63 2.59E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS07165 1127c7822ad2189b26c142c96fa4834b 199 PRINTS PR00400 Tetracycline repressor protein signature 21 44 2.3E-15 T 06-07-2017 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 CAK77_RS07165 1127c7822ad2189b26c142c96fa4834b 199 PRINTS PR00400 Tetracycline repressor protein signature 73 92 2.3E-15 T 06-07-2017 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 CAK77_RS07165 1127c7822ad2189b26c142c96fa4834b 199 PRINTS PR00400 Tetracycline repressor protein signature 186 199 2.3E-15 T 06-07-2017 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 CAK77_RS07165 1127c7822ad2189b26c142c96fa4834b 199 PRINTS PR00400 Tetracycline repressor protein signature 129 148 2.3E-15 T 06-07-2017 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 CAK77_RS07165 1127c7822ad2189b26c142c96fa4834b 199 PRINTS PR00400 Tetracycline repressor protein signature 93 116 2.3E-15 T 06-07-2017 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 CAK77_RS07165 1127c7822ad2189b26c142c96fa4834b 199 Gene3D G3DSA:1.10.357.10 75 197 1.6E-29 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS17615 164909367f13b2f0723cfa0a1c6013c5 260 PRINTS PR00412 Epoxide hydrolase signature 98 111 9.5E-6 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK77_RS17615 164909367f13b2f0723cfa0a1c6013c5 260 PRINTS PR00412 Epoxide hydrolase signature 236 258 9.5E-6 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK77_RS17615 164909367f13b2f0723cfa0a1c6013c5 260 PRINTS PR00412 Epoxide hydrolase signature 41 56 9.5E-6 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK77_RS17615 164909367f13b2f0723cfa0a1c6013c5 260 PRINTS PR00412 Epoxide hydrolase signature 84 97 9.5E-6 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK77_RS17615 164909367f13b2f0723cfa0a1c6013c5 260 Pfam PF12697 Alpha/beta hydrolase family 18 254 4.8E-21 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS17615 164909367f13b2f0723cfa0a1c6013c5 260 SUPERFAMILY SSF53474 5 259 4.52E-41 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS17615 164909367f13b2f0723cfa0a1c6013c5 260 PRINTS PR00111 Alpha/beta hydrolase fold signature 41 56 3.2E-10 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS17615 164909367f13b2f0723cfa0a1c6013c5 260 PRINTS PR00111 Alpha/beta hydrolase fold signature 84 97 3.2E-10 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS17615 164909367f13b2f0723cfa0a1c6013c5 260 PRINTS PR00111 Alpha/beta hydrolase fold signature 98 111 3.2E-10 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS17615 164909367f13b2f0723cfa0a1c6013c5 260 Gene3D G3DSA:3.40.50.1820 5 260 8.3E-42 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS11665 be3419b025afc87ed8b67016c88bd35f 157 SMART SM00240 71 121 5.5E-15 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CAK77_RS11665 be3419b025afc87ed8b67016c88bd35f 157 Pfam PF00498 FHA domain 73 135 4.5E-19 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CAK77_RS11665 be3419b025afc87ed8b67016c88bd35f 157 Gene3D G3DSA:2.60.200.20 49 150 1.1E-29 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CAK77_RS11665 be3419b025afc87ed8b67016c88bd35f 157 SUPERFAMILY SSF49879 32 144 3.83E-31 T 06-07-2017 IPR008984 SMAD/FHA domain GO:0005515 CAK77_RS10920 ed1542ed90d1194e579114c9ef4e3a6b 75 SUPERFAMILY SSF54862 7 68 2.35E-15 T 06-07-2017 CAK77_RS10920 ed1542ed90d1194e579114c9ef4e3a6b 75 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 51 62 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CAK77_RS10920 ed1542ed90d1194e579114c9ef4e3a6b 75 Pfam PF12838 4Fe-4S dicluster domain 19 65 8.8E-10 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CAK77_RS10920 ed1542ed90d1194e579114c9ef4e3a6b 75 Gene3D G3DSA:3.30.70.20 12 68 1.8E-15 T 06-07-2017 CAK77_RS01490 12fea9725c8d2df878a35cee343d485f 642 Gene3D G3DSA:3.50.50.60 556 603 7.7E-10 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS01490 12fea9725c8d2df878a35cee343d485f 642 Gene3D G3DSA:3.50.50.60 2 192 7.7E-10 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS01490 12fea9725c8d2df878a35cee343d485f 642 SUPERFAMILY SSF51905 108 321 6.04E-7 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS01490 12fea9725c8d2df878a35cee343d485f 642 SUPERFAMILY SSF51905 2 76 6.04E-7 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS01490 12fea9725c8d2df878a35cee343d485f 642 Pfam PF13454 FAD-NAD(P)-binding 7 190 1.5E-46 T 06-07-2017 CAK77_RS16170 19324bd9e2b7502ca8e4ba1bcebfeff0 224 Gene3D G3DSA:1.10.10.10 123 223 2.6E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS16170 19324bd9e2b7502ca8e4ba1bcebfeff0 224 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 222 3.1E-20 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAK77_RS16170 19324bd9e2b7502ca8e4ba1bcebfeff0 224 Pfam PF00072 Response regulator receiver domain 4 112 4.3E-28 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK77_RS16170 19324bd9e2b7502ca8e4ba1bcebfeff0 224 SUPERFAMILY SSF52172 1 182 9.25E-44 T 06-07-2017 IPR011006 CheY-like superfamily CAK77_RS16170 19324bd9e2b7502ca8e4ba1bcebfeff0 224 Gene3D G3DSA:3.40.50.2300 1 121 4.9E-39 T 06-07-2017 CAK77_RS16170 19324bd9e2b7502ca8e4ba1bcebfeff0 224 SMART SM00448 2 112 6.6E-43 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK77_RS16170 19324bd9e2b7502ca8e4ba1bcebfeff0 224 SMART SM00862 146 222 2.9E-21 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAK77_RS14790 91944a38bf0d07e9e74b23bf2a08cf84 179 Pfam PF00583 Acetyltransferase (GNAT) family 65 152 9.8E-14 T 06-07-2017 IPR000182 GNAT domain GO:0008080 CAK77_RS14790 91944a38bf0d07e9e74b23bf2a08cf84 179 Gene3D G3DSA:3.40.630.30 1 176 4.1E-31 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS14790 91944a38bf0d07e9e74b23bf2a08cf84 179 SUPERFAMILY SSF55729 1 173 2.4E-27 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS10910 5b4636e2d604e55f047aa645efffe7c1 289 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 4.4E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK77_RS10910 5b4636e2d604e55f047aa645efffe7c1 289 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 4.4E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK77_RS10910 5b4636e2d604e55f047aa645efffe7c1 289 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 4.4E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK77_RS10910 5b4636e2d604e55f047aa645efffe7c1 289 Pfam PF03466 LysR substrate binding domain 88 288 5.6E-40 T 06-07-2017 IPR005119 LysR, substrate-binding CAK77_RS10910 5b4636e2d604e55f047aa645efffe7c1 289 Gene3D G3DSA:1.10.10.10 1 86 6.3E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS10910 5b4636e2d604e55f047aa645efffe7c1 289 SUPERFAMILY SSF53850 90 288 3.74E-36 T 06-07-2017 CAK77_RS10910 5b4636e2d604e55f047aa645efffe7c1 289 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 2.0E-23 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK77_RS10910 5b4636e2d604e55f047aa645efffe7c1 289 Gene3D G3DSA:3.40.190.10 90 175 1.4E-13 T 06-07-2017 CAK77_RS10910 5b4636e2d604e55f047aa645efffe7c1 289 SUPERFAMILY SSF46785 1 85 3.72E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS10910 5b4636e2d604e55f047aa645efffe7c1 289 Gene3D G3DSA:3.40.190.10 176 258 5.3E-24 T 06-07-2017 CAK77_RS11080 a1a6bbbd227a6084507fd33380107593 425 Gene3D G3DSA:3.90.1150.10 302 415 8.0E-24 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK77_RS11080 a1a6bbbd227a6084507fd33380107593 425 SUPERFAMILY SSF53383 40 413 9.94E-99 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK77_RS11080 a1a6bbbd227a6084507fd33380107593 425 Gene3D G3DSA:3.40.640.10 70 301 1.2E-77 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK77_RS11080 a1a6bbbd227a6084507fd33380107593 425 Pfam PF00202 Aminotransferase class-III 40 407 1.5E-84 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAK77_RS11080 a1a6bbbd227a6084507fd33380107593 425 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 230 267 - T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAK77_RS13000 4aa288482ec1336f02581c7aee280ed6 346 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 16 274 4.8E-62 T 06-07-2017 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CAK77_RS13000 4aa288482ec1336f02581c7aee280ed6 346 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 144 156 - T 06-07-2017 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CAK77_RS13000 4aa288482ec1336f02581c7aee280ed6 346 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 11 280 15.149 T 06-07-2017 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CAK77_RS13000 4aa288482ec1336f02581c7aee280ed6 346 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 16 273 1.1E-39 T 06-07-2017 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CAK77_RS17285 4c8de19efab353fc3dace3231d25e386 123 SUPERFAMILY SSF46955 33 118 1.47E-19 T 06-07-2017 IPR009061 Putative DNA-binding domain CAK77_RS17285 4c8de19efab353fc3dace3231d25e386 123 Pfam PF13411 MerR HTH family regulatory protein 33 98 9.2E-16 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAK77_RS17285 4c8de19efab353fc3dace3231d25e386 123 SMART SM00422 33 101 7.2E-20 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAK77_RS17285 4c8de19efab353fc3dace3231d25e386 123 Gene3D G3DSA:1.10.1660.10 34 118 2.3E-21 T 06-07-2017 CAK77_RS22650 c08543648b85000a1ed89e09cf2368ea 272 SUPERFAMILY SSF53474 8 268 1.77E-46 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS22650 c08543648b85000a1ed89e09cf2368ea 272 PRINTS PR00111 Alpha/beta hydrolase fold signature 101 114 2.6E-8 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS22650 c08543648b85000a1ed89e09cf2368ea 272 PRINTS PR00111 Alpha/beta hydrolase fold signature 115 128 2.6E-8 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS22650 c08543648b85000a1ed89e09cf2368ea 272 PRINTS PR00111 Alpha/beta hydrolase fold signature 213 227 2.6E-8 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS22650 c08543648b85000a1ed89e09cf2368ea 272 PRINTS PR00111 Alpha/beta hydrolase fold signature 52 67 2.6E-8 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS22650 c08543648b85000a1ed89e09cf2368ea 272 Gene3D G3DSA:3.40.50.1820 5 271 9.4E-50 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS22650 c08543648b85000a1ed89e09cf2368ea 272 Pfam PF12146 Serine aminopeptidase, S33 23 254 4.1E-75 T 06-07-2017 IPR022742 Serine aminopeptidase, S33 CAK77_RS09315 bb7f379778cd9e6a49a47e5990c5f76e 111 Pfam PF16525 Haemophore, haem-binding 30 107 7.4E-23 T 06-07-2017 IPR032407 Haemophore, haem-binding GO:0020037 CAK77_RS09315 bb7f379778cd9e6a49a47e5990c5f76e 111 TIGRFAM TIGR04529 MTB_hemophore: hemophore-related protein, Rv0203/Rv1174c family 31 109 1.7E-20 T 06-07-2017 IPR032407 Haemophore, haem-binding GO:0020037 CAK77_RS24105 669d22029788f1c3797a84ebf0a09373 793 SUPERFAMILY SSF53955 131 336 2.7E-61 T 06-07-2017 IPR023346 Lysozyme-like domain CAK77_RS24105 669d22029788f1c3797a84ebf0a09373 793 SUPERFAMILY SSF56601 305 327 3.76E-87 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK77_RS24105 669d22029788f1c3797a84ebf0a09373 793 SUPERFAMILY SSF56601 359 723 3.76E-87 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK77_RS24105 669d22029788f1c3797a84ebf0a09373 793 Gene3D G3DSA:1.10.3810.10 154 323 2.2E-59 T 06-07-2017 CAK77_RS24105 669d22029788f1c3797a84ebf0a09373 793 Pfam PF00912 Transglycosylase 153 323 9.3E-56 T 06-07-2017 IPR001264 Glycosyl transferase, family 51 CAK77_RS24105 669d22029788f1c3797a84ebf0a09373 793 Gene3D G3DSA:3.40.710.10 324 722 1.5E-94 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK77_RS24105 669d22029788f1c3797a84ebf0a09373 793 Pfam PF00905 Penicillin binding protein transpeptidase domain 417 675 1.4E-27 T 06-07-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CAK77_RS13375 bdb120fc0addb3f82e9d8b3c67959d8c 962 Gene3D G3DSA:3.30.499.10 58 271 1.5E-78 T 06-07-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CAK77_RS13375 bdb120fc0addb3f82e9d8b3c67959d8c 962 ProSitePatterns PS01244 Aconitase family signature 2. 557 570 - T 06-07-2017 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CAK77_RS13375 bdb120fc0addb3f82e9d8b3c67959d8c 962 Gene3D G3DSA:3.20.19.10 701 960 1.3E-77 T 06-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CAK77_RS13375 bdb120fc0addb3f82e9d8b3c67959d8c 962 ProSitePatterns PS00450 Aconitase family signature 1. 491 507 - T 06-07-2017 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CAK77_RS13375 bdb120fc0addb3f82e9d8b3c67959d8c 962 Pfam PF00694 Aconitase C-terminal domain 755 885 1.0E-42 T 06-07-2017 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 CAK77_RS13375 bdb120fc0addb3f82e9d8b3c67959d8c 962 SUPERFAMILY SSF52016 695 960 2.55E-81 T 06-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CAK77_RS13375 bdb120fc0addb3f82e9d8b3c67959d8c 962 Gene3D G3DSA:3.40.1060.10 272 389 2.4E-35 T 06-07-2017 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 CAK77_RS13375 bdb120fc0addb3f82e9d8b3c67959d8c 962 PRINTS PR00415 Aconitase family signature 315 328 7.4E-41 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAK77_RS13375 bdb120fc0addb3f82e9d8b3c67959d8c 962 PRINTS PR00415 Aconitase family signature 239 254 7.4E-41 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAK77_RS13375 bdb120fc0addb3f82e9d8b3c67959d8c 962 PRINTS PR00415 Aconitase family signature 301 314 7.4E-41 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAK77_RS13375 bdb120fc0addb3f82e9d8b3c67959d8c 962 PRINTS PR00415 Aconitase family signature 172 185 7.4E-41 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAK77_RS13375 bdb120fc0addb3f82e9d8b3c67959d8c 962 PRINTS PR00415 Aconitase family signature 394 408 7.4E-41 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAK77_RS13375 bdb120fc0addb3f82e9d8b3c67959d8c 962 PRINTS PR00415 Aconitase family signature 196 204 7.4E-41 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAK77_RS13375 bdb120fc0addb3f82e9d8b3c67959d8c 962 PRINTS PR00415 Aconitase family signature 225 238 7.4E-41 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAK77_RS13375 bdb120fc0addb3f82e9d8b3c67959d8c 962 PRINTS PR00415 Aconitase family signature 557 570 7.4E-41 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAK77_RS13375 bdb120fc0addb3f82e9d8b3c67959d8c 962 PRINTS PR00415 Aconitase family signature 495 506 7.4E-41 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAK77_RS13375 bdb120fc0addb3f82e9d8b3c67959d8c 962 SUPERFAMILY SSF53732 34 428 7.19E-224 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAK77_RS13375 bdb120fc0addb3f82e9d8b3c67959d8c 962 SUPERFAMILY SSF53732 465 691 7.19E-224 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAK77_RS13375 bdb120fc0addb3f82e9d8b3c67959d8c 962 Pfam PF00330 Aconitase family (aconitate hydratase) 103 626 1.4E-174 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAK77_RS13375 bdb120fc0addb3f82e9d8b3c67959d8c 962 Gene3D G3DSA:3.30.499.10 483 639 3.1E-63 T 06-07-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CAK77_RS13375 bdb120fc0addb3f82e9d8b3c67959d8c 962 Gene3D G3DSA:3.30.499.10 390 415 3.1E-63 T 06-07-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CAK77_RS13375 bdb120fc0addb3f82e9d8b3c67959d8c 962 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 59 960 0.0 T 06-07-2017 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3 CAK77_RS03460 1dea9d31881a627ee10b51a11e9c4e02 268 PIRSF PIRSF028177 2 266 1.5E-61 T 06-07-2017 IPR016874 Tetracenomycin polyketide synthesis O-methyltransferase TcmP GO:0017000|GO:1901106 CAK77_RS03460 1dea9d31881a627ee10b51a11e9c4e02 268 SUPERFAMILY SSF53335 12 251 9.97E-43 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS03460 1dea9d31881a627ee10b51a11e9c4e02 268 Gene3D G3DSA:3.40.50.150 12 185 2.0E-20 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS03460 1dea9d31881a627ee10b51a11e9c4e02 268 Pfam PF04072 Leucine carboxyl methyltransferase 17 163 4.9E-7 T 06-07-2017 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 CAK77_RS20195 de2ba90101ce43d9a56d4643b156c058 337 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 12 276 1.8E-49 T 06-07-2017 IPR005693 Virulence factor Mce protein CAK77_RS20195 de2ba90101ce43d9a56d4643b156c058 337 Pfam PF02470 MlaD protein 39 110 8.7E-16 T 06-07-2017 IPR003399 Mce/MlaD CAK77_RS12790 a07329466cc3e971115a580cfa2ecda5 332 SUPERFAMILY SSF160240 253 331 7.06E-15 T 06-07-2017 CAK77_RS12790 a07329466cc3e971115a580cfa2ecda5 332 Pfam PF01545 Cation efflux family 58 250 2.0E-38 T 06-07-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CAK77_RS12790 a07329466cc3e971115a580cfa2ecda5 332 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 54 331 5.4E-70 T 06-07-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CAK77_RS12790 a07329466cc3e971115a580cfa2ecda5 332 Pfam PF16916 Dimerisation domain of Zinc Transporter 255 330 8.9E-15 T 06-07-2017 IPR027470 Cation efflux protein, cytoplasmic domain CAK77_RS12790 a07329466cc3e971115a580cfa2ecda5 332 Gene3D G3DSA:1.20.1510.10 54 250 1.2E-40 T 06-07-2017 IPR027469 Cation efflux protein transmembrane domain CAK77_RS12790 a07329466cc3e971115a580cfa2ecda5 332 Gene3D G3DSA:3.30.70.1350 251 331 1.2E-17 T 06-07-2017 IPR027470 Cation efflux protein, cytoplasmic domain CAK77_RS12790 a07329466cc3e971115a580cfa2ecda5 332 SUPERFAMILY SSF161111 53 251 3.66E-47 T 06-07-2017 CAK77_RS05070 32e26e2bf026399f9c876c9e972b94f6 352 Pfam PF02470 MlaD protein 37 110 4.6E-15 T 06-07-2017 IPR003399 Mce/MlaD CAK77_RS05070 32e26e2bf026399f9c876c9e972b94f6 352 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 11 266 1.2E-49 T 06-07-2017 IPR005693 Virulence factor Mce protein CAK77_RS10165 d2709b757afac3e4e756a064e5fb4510 591 Pfam PF00899 ThiF family 341 460 1.1E-16 T 06-07-2017 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CAK77_RS10165 d2709b757afac3e4e756a064e5fb4510 591 Pfam PF14457 Prokaryotic E2 family A 23 142 5.2E-9 T 06-07-2017 IPR032865 Prokaryotic E2 family A CAK77_RS10165 d2709b757afac3e4e756a064e5fb4510 591 Gene3D G3DSA:3.40.50.720 341 491 5.2E-17 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS10165 d2709b757afac3e4e756a064e5fb4510 591 SUPERFAMILY SSF69572 341 452 1.18E-21 T 06-07-2017 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CAK77_RS12060 7d15ddf5ec37261cd7e7609a98081860 445 SUPERFAMILY SSF103473 23 437 1.57E-54 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK77_RS12060 7d15ddf5ec37261cd7e7609a98081860 445 Gene3D G3DSA:1.20.1250.20 251 438 1.7E-18 T 06-07-2017 CAK77_RS12060 7d15ddf5ec37261cd7e7609a98081860 445 Gene3D G3DSA:1.20.1250.20 29 225 7.0E-18 T 06-07-2017 CAK77_RS12060 7d15ddf5ec37261cd7e7609a98081860 445 Pfam PF00083 Sugar (and other) transporter 27 434 2.1E-25 T 06-07-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CAK77_RS12060 7d15ddf5ec37261cd7e7609a98081860 445 ProSitePatterns PS00217 Sugar transport proteins signature 2. 137 162 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CAK77_RS22960 6d1bb3ffc9df0d4b9d4e12e4a7c951ea 225 Gene3D G3DSA:3.40.50.150 22 209 1.8E-39 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS22960 6d1bb3ffc9df0d4b9d4e12e4a7c951ea 225 Pfam PF13649 Methyltransferase domain 64 153 3.3E-20 T 06-07-2017 CAK77_RS22960 6d1bb3ffc9df0d4b9d4e12e4a7c951ea 225 SUPERFAMILY SSF53335 25 212 1.4E-39 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS03610 16a3c0bbe2a23ebeee6838ac75a93c70 79 TIGRFAM TIGR00302 TIGR00302: phosphoribosylformylglycinamidine synthase, purS protein 4 75 4.1E-16 T 06-07-2017 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CAK77_RS03610 16a3c0bbe2a23ebeee6838ac75a93c70 79 Hamap MF_01926 Phosphoribosylformylglycinamidine synthase subunit PurS [purS]. 2 76 19.818 T 06-07-2017 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CAK77_RS03610 16a3c0bbe2a23ebeee6838ac75a93c70 79 SUPERFAMILY SSF82697 3 76 1.15E-22 T 06-07-2017 CAK77_RS03610 16a3c0bbe2a23ebeee6838ac75a93c70 79 ProDom PD010362 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE PURS SYNTHETASE SYNTHASE COMPONENT SYNTHASE LIGASE FGAM UPF0062 I 11 74 7.0E-22 T 06-07-2017 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CAK77_RS03610 16a3c0bbe2a23ebeee6838ac75a93c70 79 Gene3D G3DSA:3.30.1280.10 3 76 2.9E-29 T 06-07-2017 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CAK77_RS03610 16a3c0bbe2a23ebeee6838ac75a93c70 79 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 4 74 1.8E-25 T 06-07-2017 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CAK77_RS21110 0e7258844f94b437d709fcd899dd87f6 497 Pfam PF04389 Peptidase family M28 249 465 6.6E-40 T 06-07-2017 IPR007484 Peptidase M28 CAK77_RS21110 0e7258844f94b437d709fcd899dd87f6 497 Gene3D G3DSA:3.40.630.10 47 108 5.6E-57 T 06-07-2017 CAK77_RS21110 0e7258844f94b437d709fcd899dd87f6 497 Gene3D G3DSA:3.40.630.10 247 471 5.6E-57 T 06-07-2017 CAK77_RS21110 0e7258844f94b437d709fcd899dd87f6 497 SUPERFAMILY SSF53187 232 475 2.06E-55 T 06-07-2017 CAK77_RS21110 0e7258844f94b437d709fcd899dd87f6 497 SUPERFAMILY SSF53187 46 97 2.06E-55 T 06-07-2017 CAK77_RS21110 0e7258844f94b437d709fcd899dd87f6 497 SUPERFAMILY SSF52025 122 196 3.79E-7 T 06-07-2017 CAK77_RS21110 0e7258844f94b437d709fcd899dd87f6 497 Gene3D G3DSA:3.50.30.30 128 220 9.1E-8 T 06-07-2017 CAK77_RS21110 0e7258844f94b437d709fcd899dd87f6 497 Pfam PF02225 PA domain 148 219 5.6E-7 T 06-07-2017 IPR003137 PA domain CAK77_RS13055 e1dcb932c6cfa2666805bdf44f9943fc 116 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 8 111 30.347 T 06-07-2017 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 CAK77_RS13055 e1dcb932c6cfa2666805bdf44f9943fc 116 SUPERFAMILY SSF141734 8 110 4.58E-46 T 06-07-2017 CAK77_RS13055 e1dcb932c6cfa2666805bdf44f9943fc 116 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 57 111 4.0E-20 T 06-07-2017 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 CAK77_RS13055 e1dcb932c6cfa2666805bdf44f9943fc 116 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 34 106 6.1E-35 T 06-07-2017 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 CAK77_RS15105 e8c1c0c4d40ec566ef6ec8751612a6d0 359 Pfam PF00561 alpha/beta hydrolase fold 56 300 8.3E-27 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS15105 e8c1c0c4d40ec566ef6ec8751612a6d0 359 PRINTS PR00412 Epoxide hydrolase signature 81 96 5.1E-6 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK77_RS15105 e8c1c0c4d40ec566ef6ec8751612a6d0 359 PRINTS PR00412 Epoxide hydrolase signature 255 271 5.1E-6 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK77_RS15105 e8c1c0c4d40ec566ef6ec8751612a6d0 359 PRINTS PR00412 Epoxide hydrolase signature 288 310 5.1E-6 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK77_RS15105 e8c1c0c4d40ec566ef6ec8751612a6d0 359 SUPERFAMILY SSF53474 36 314 1.28E-61 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS15105 e8c1c0c4d40ec566ef6ec8751612a6d0 359 Gene3D G3DSA:3.40.50.1820 39 314 1.4E-62 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS15105 e8c1c0c4d40ec566ef6ec8751612a6d0 359 PRINTS PR00111 Alpha/beta hydrolase fold signature 125 138 8.9E-12 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS15105 e8c1c0c4d40ec566ef6ec8751612a6d0 359 PRINTS PR00111 Alpha/beta hydrolase fold signature 81 96 8.9E-12 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS15105 e8c1c0c4d40ec566ef6ec8751612a6d0 359 PRINTS PR00111 Alpha/beta hydrolase fold signature 139 152 8.9E-12 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS20320 0a042f07df30194ef6e61cf329d4cc00 167 Pfam PF10722 Putative bacterial sensory transduction regulator 11 133 1.5E-22 T 06-07-2017 IPR019660 Putative sensory transduction regulator YbjN CAK77_RS20320 0a042f07df30194ef6e61cf329d4cc00 167 SUPERFAMILY SSF69635 11 136 3.66E-25 T 06-07-2017 CAK77_RS20320 0a042f07df30194ef6e61cf329d4cc00 167 Gene3D G3DSA:3.30.1460.10 40 147 3.6E-14 T 06-07-2017 CAK77_RS23440 35c45f0a1c9aa4c4f21dcd02c384e0a7 422 Gene3D G3DSA:3.40.50.1820 112 291 8.3E-15 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS23440 35c45f0a1c9aa4c4f21dcd02c384e0a7 422 Gene3D G3DSA:3.40.50.1820 335 420 8.3E-15 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS23440 35c45f0a1c9aa4c4f21dcd02c384e0a7 422 SUPERFAMILY SSF53474 117 417 2.37E-15 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS23440 35c45f0a1c9aa4c4f21dcd02c384e0a7 422 Pfam PF03583 Secretory lipase 173 418 2.0E-34 T 06-07-2017 IPR005152 Lipase, secreted GO:0004806|GO:0016042 KEGG: 00561+3.1.1.3|MetaCyc: PWY-6857 CAK77_RS23440 35c45f0a1c9aa4c4f21dcd02c384e0a7 422 PIRSF PIRSF029171 13 422 1.5E-27 T 06-07-2017 IPR005152 Lipase, secreted GO:0004806|GO:0016042 KEGG: 00561+3.1.1.3|MetaCyc: PWY-6857 CAK77_RS21350 26c1529a5f98a771dfa51083b63c6e6e 241 SUPERFAMILY SSF54637 47 234 6.99E-43 T 06-07-2017 IPR029069 HotDog domain CAK77_RS21350 26c1529a5f98a771dfa51083b63c6e6e 241 Gene3D G3DSA:3.10.129.10 117 238 6.9E-29 T 06-07-2017 IPR029069 HotDog domain CAK77_RS21350 26c1529a5f98a771dfa51083b63c6e6e 241 Pfam PF03061 Thioesterase superfamily 151 226 7.9E-10 T 06-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 CAK77_RS23390 375fb03ba017a0e497d1aae3d662435d 262 Pfam PF11139 Sap, sulfolipid-1-addressing protein 5 259 8.8E-53 T 06-07-2017 IPR021315 Glycolipid exporter Gap/Sap CAK77_RS16290 7d39fe535ec8f9637f8c01db87e6212b 213 Pfam PF01083 Cutinase 8 202 1.0E-47 T 06-07-2017 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 CAK77_RS16290 7d39fe535ec8f9637f8c01db87e6212b 213 SMART SM01110 7 202 4.9E-94 T 06-07-2017 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 CAK77_RS16290 7d39fe535ec8f9637f8c01db87e6212b 213 Gene3D G3DSA:3.40.50.1820 8 202 1.7E-53 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS16290 7d39fe535ec8f9637f8c01db87e6212b 213 SUPERFAMILY SSF53474 9 202 3.34E-40 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS05055 21423f8e3240102b78a746870b70d286 436 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 160 259 6.9E-9 T 06-07-2017 IPR024516 Mammalian cell entry, C-terminal CAK77_RS05055 21423f8e3240102b78a746870b70d286 436 Pfam PF02470 MlaD protein 40 114 8.6E-12 T 06-07-2017 IPR003399 Mce/MlaD CAK77_RS08525 ff93ee4d4cfb46061c63bc7d655ffcf4 272 Pfam PF04480 Protein of unknown function (DUF559) 205 265 2.5E-6 T 06-07-2017 IPR007569 Domain of unknown function DUF559 CAK77_RS08525 ff93ee4d4cfb46061c63bc7d655ffcf4 272 SUPERFAMILY SSF52980 157 267 2.47E-7 T 06-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CAK77_RS20685 b91b626313675a48d59205d350ea3b36 166 Pfam PF00484 Carbonic anhydrase 32 108 1.9E-12 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CAK77_RS20685 b91b626313675a48d59205d350ea3b36 166 SUPERFAMILY SSF53056 5 162 7.46E-38 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CAK77_RS20685 b91b626313675a48d59205d350ea3b36 166 Gene3D G3DSA:3.40.1050.10 4 163 5.6E-37 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CAK77_RS20685 b91b626313675a48d59205d350ea3b36 166 SMART SM00947 24 163 1.1E-26 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CAK77_RS17710 3311d074018d2304c01ef104d2c8d989 161 Gene3D G3DSA:3.40.630.30 4 159 6.7E-56 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS17710 3311d074018d2304c01ef104d2c8d989 161 SUPERFAMILY SSF55729 5 152 4.63E-36 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS17710 3311d074018d2304c01ef104d2c8d989 161 Pfam PF00583 Acetyltransferase (GNAT) family 58 137 7.0E-15 T 06-07-2017 IPR000182 GNAT domain GO:0008080 CAK77_RS22205 246a68b85bc974488430c56e071763c6 120 SUPERFAMILY SSF54909 3 111 2.01E-24 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAK77_RS22205 246a68b85bc974488430c56e071763c6 120 Gene3D G3DSA:3.30.70.1060 1 111 1.2E-32 T 06-07-2017 CAK77_RS22205 246a68b85bc974488430c56e071763c6 120 Pfam PF03795 YCII-related domain 3 100 1.1E-13 T 06-07-2017 IPR005545 YCII-related CAK77_RS06590 11e0771a773b4634b4b452dc8891263f 600 Gene3D G3DSA:3.10.105.10 513 564 1.1E-21 T 06-07-2017 CAK77_RS06590 11e0771a773b4634b4b452dc8891263f 600 Gene3D G3DSA:3.10.105.10 313 480 1.1E-21 T 06-07-2017 CAK77_RS06590 11e0771a773b4634b4b452dc8891263f 600 Gene3D G3DSA:3.40.190.10 211 312 3.5E-10 T 06-07-2017 CAK77_RS06590 11e0771a773b4634b4b452dc8891263f 600 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 100 469 7.3E-35 T 06-07-2017 IPR000914 Solute-binding protein family 5 domain CAK77_RS06590 11e0771a773b4634b4b452dc8891263f 600 SUPERFAMILY SSF53850 516 581 2.9E-61 T 06-07-2017 CAK77_RS06590 11e0771a773b4634b4b452dc8891263f 600 SUPERFAMILY SSF53850 43 488 2.9E-61 T 06-07-2017 CAK77_RS06590 11e0771a773b4634b4b452dc8891263f 600 Gene3D G3DSA:3.90.76.10 60 200 1.1E-15 T 06-07-2017 CAK77_RS09980 1a9bd4e096cc0db138925dccbec49b08 155 PIRSF PIRSF018072 2 154 6.6E-33 T 06-07-2017 IPR016709 Uncharacterised protein family UPF0336 CAK77_RS09980 1a9bd4e096cc0db138925dccbec49b08 155 Pfam PF13452 N-terminal half of MaoC dehydratase 9 142 2.9E-35 T 06-07-2017 CAK77_RS09980 1a9bd4e096cc0db138925dccbec49b08 155 SUPERFAMILY SSF54637 9 151 5.81E-28 T 06-07-2017 IPR029069 HotDog domain CAK77_RS09980 1a9bd4e096cc0db138925dccbec49b08 155 Gene3D G3DSA:3.10.129.10 10 144 2.6E-25 T 06-07-2017 IPR029069 HotDog domain CAK77_RS12075 56c94bd62410a81f9b4206ddee03d367 278 SUPERFAMILY SSF144064 4 276 3.53E-48 T 06-07-2017 CAK77_RS12075 56c94bd62410a81f9b4206ddee03d367 278 Pfam PF05171 Haemin-degrading HemS.ChuX domain 156 273 5.7E-6 T 06-07-2017 IPR007845 Haemin-degrading HemS/ChuX domain GO:0006826 CAK77_RS12795 05009276be1e307f49e56bbea2f0dae3 124 SUPERFAMILY SSF46785 9 93 1.35E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS12795 05009276be1e307f49e56bbea2f0dae3 124 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 68 83 8.6E-14 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK77_RS12795 05009276be1e307f49e56bbea2f0dae3 124 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 40 51 8.6E-14 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK77_RS12795 05009276be1e307f49e56bbea2f0dae3 124 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 53 68 8.6E-14 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK77_RS12795 05009276be1e307f49e56bbea2f0dae3 124 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 21 36 8.6E-14 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK77_RS12795 05009276be1e307f49e56bbea2f0dae3 124 Gene3D G3DSA:1.10.10.10 5 97 4.0E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS12795 05009276be1e307f49e56bbea2f0dae3 124 Pfam PF12840 Helix-turn-helix domain 19 76 2.3E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS12795 05009276be1e307f49e56bbea2f0dae3 124 SMART SM00418 19 97 1.3E-29 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK77_RS12780 bc15c23a5afbd744f17a7c61430eab45 111 Pfam PF02694 Uncharacterised BCR, YnfA/UPF0060 family 4 110 1.0E-43 T 06-07-2017 IPR003844 Uncharacterised protein family UPF0060 GO:0016020 CAK77_RS12780 bc15c23a5afbd744f17a7c61430eab45 111 SUPERFAMILY SSF103481 9 107 5.75E-8 T 06-07-2017 CAK77_RS12780 bc15c23a5afbd744f17a7c61430eab45 111 Hamap MF_00010 UPF0060 membrane protein YnfA [ynfA]. 4 109 20.827 T 06-07-2017 IPR003844 Uncharacterised protein family UPF0060 GO:0016020 CAK77_RS23045 be4c8aca35a5e1011e292b059653e4ce 282 Pfam PF10708 Protein of unknown function (DUF2510) 9 37 7.8E-7 T 06-07-2017 IPR018929 Domain of unknown function DUF2510 CAK77_RS23045 be4c8aca35a5e1011e292b059653e4ce 282 Gene3D G3DSA:3.60.160.10 73 274 6.0E-44 T 06-07-2017 IPR002838 Mitochondrial biogenesis protein AIM24 CAK77_RS23045 be4c8aca35a5e1011e292b059653e4ce 282 Pfam PF01987 Mitochondrial biogenesis AIM24 80 272 1.1E-34 T 06-07-2017 IPR002838 Mitochondrial biogenesis protein AIM24 CAK77_RS23045 be4c8aca35a5e1011e292b059653e4ce 282 SUPERFAMILY SSF51219 80 276 8.63E-48 T 06-07-2017 IPR016031 Tryptophan RNA-binding attenuator protein-like domain CAK77_RS22215 a4ad0deedcbeca06a4ee544d22848533 611 SUPERFAMILY SSF56801 27 608 4.84E-95 T 06-07-2017 CAK77_RS22215 a4ad0deedcbeca06a4ee544d22848533 611 Gene3D G3DSA:3.40.50.980 59 198 6.1E-25 T 06-07-2017 CAK77_RS22215 a4ad0deedcbeca06a4ee544d22848533 611 Pfam PF00501 AMP-binding enzyme 44 494 2.6E-70 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK77_RS22215 a4ad0deedcbeca06a4ee544d22848533 611 Gene3D G3DSA:3.30.300.30 486 605 1.0E-11 T 06-07-2017 CAK77_RS22215 a4ad0deedcbeca06a4ee544d22848533 611 Gene3D G3DSA:3.40.50.980 199 363 1.7E-24 T 06-07-2017 CAK77_RS22215 a4ad0deedcbeca06a4ee544d22848533 611 Gene3D G3DSA:2.30.38.10 393 485 7.7E-18 T 06-07-2017 CAK77_RS17840 4b1ed7b7b392eef7995511bef6687763 584 SMART SM00909 198 295 2.8E-7 T 06-07-2017 IPR019606 GerMN domain CAK77_RS17840 4b1ed7b7b392eef7995511bef6687763 584 Pfam PF10647 Lipoprotein LpqB beta-propeller domain 325 582 9.5E-65 T 06-07-2017 IPR018910 Lipoprotein LpqB, beta-propeller domain, C-terminal CAK77_RS17840 4b1ed7b7b392eef7995511bef6687763 584 Hamap MF_01373 Lipoprotein LpqB [lpqB]. 1 584 22.711 T 06-07-2017 IPR023959 Lipoprotein LpqB CAK77_RS17840 4b1ed7b7b392eef7995511bef6687763 584 Pfam PF10646 Sporulation and spore germination 171 292 4.9E-10 T 06-07-2017 IPR019606 GerMN domain CAK77_RS14610 c95ad15964fe6db8ffb34684582ffa50 302 Pfam PF01014 Uricase 148 279 1.5E-29 T 06-07-2017 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 CAK77_RS14610 c95ad15964fe6db8ffb34684582ffa50 302 Pfam PF01014 Uricase 9 133 1.7E-21 T 06-07-2017 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 CAK77_RS14610 c95ad15964fe6db8ffb34684582ffa50 302 PRINTS PR00093 Uricase signature 86 99 5.5E-17 T 06-07-2017 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 CAK77_RS14610 c95ad15964fe6db8ffb34684582ffa50 302 PRINTS PR00093 Uricase signature 152 168 5.5E-17 T 06-07-2017 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 CAK77_RS14610 c95ad15964fe6db8ffb34684582ffa50 302 PRINTS PR00093 Uricase signature 11 22 5.5E-17 T 06-07-2017 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 CAK77_RS14610 c95ad15964fe6db8ffb34684582ffa50 302 PRINTS PR00093 Uricase signature 50 64 5.5E-17 T 06-07-2017 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 CAK77_RS14610 c95ad15964fe6db8ffb34684582ffa50 302 PRINTS PR00093 Uricase signature 168 180 5.5E-17 T 06-07-2017 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 CAK77_RS14610 c95ad15964fe6db8ffb34684582ffa50 302 PIRSF PIRSF000241 2 290 9.1E-95 T 06-07-2017 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 CAK77_RS14610 c95ad15964fe6db8ffb34684582ffa50 302 Gene3D G3DSA:3.10.270.10 3 288 8.0E-106 T 06-07-2017 CAK77_RS14610 c95ad15964fe6db8ffb34684582ffa50 302 TIGRFAM TIGR03383 urate_oxi: urate oxidase 6 284 4.6E-107 T 06-07-2017 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 CAK77_RS14610 c95ad15964fe6db8ffb34684582ffa50 302 SUPERFAMILY SSF55620 143 295 3.78E-56 T 06-07-2017 CAK77_RS14610 c95ad15964fe6db8ffb34684582ffa50 302 SUPERFAMILY SSF55620 3 131 1.05E-47 T 06-07-2017 CAK77_RS14610 c95ad15964fe6db8ffb34684582ffa50 302 ProSitePatterns PS00366 Uricase signature. 152 179 - T 06-07-2017 IPR019842 Uricase, conserved site GO:0004846|GO:0006144|GO:0055114 KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 CAK77_RS14610 c95ad15964fe6db8ffb34684582ffa50 302 ProDom PD003367 URICASE OXIDOREDUCTASE URATE OXIDASE METABOLISM PURINE PEROXISOME ACETYLATION II DIRECT 182 284 1.0E-33 T 06-07-2017 CAK77_RS22510 065fe2fa4652a7eeb0eb3d721a6fb47d 292 Gene3D G3DSA:3.40.50.1820 6 286 9.8E-66 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS22510 065fe2fa4652a7eeb0eb3d721a6fb47d 292 SUPERFAMILY SSF53474 8 286 1.17E-64 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS22510 065fe2fa4652a7eeb0eb3d721a6fb47d 292 Pfam PF00561 alpha/beta hydrolase fold 36 158 5.5E-26 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS22510 065fe2fa4652a7eeb0eb3d721a6fb47d 292 PRINTS PR00111 Alpha/beta hydrolase fold signature 231 245 3.5E-7 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS22510 065fe2fa4652a7eeb0eb3d721a6fb47d 292 PRINTS PR00111 Alpha/beta hydrolase fold signature 61 76 3.5E-7 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS22510 065fe2fa4652a7eeb0eb3d721a6fb47d 292 PRINTS PR00111 Alpha/beta hydrolase fold signature 119 132 3.5E-7 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS22510 065fe2fa4652a7eeb0eb3d721a6fb47d 292 PRINTS PR00111 Alpha/beta hydrolase fold signature 105 118 3.5E-7 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS22510 065fe2fa4652a7eeb0eb3d721a6fb47d 292 PRINTS PR00412 Epoxide hydrolase signature 229 245 1.1E-17 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK77_RS22510 065fe2fa4652a7eeb0eb3d721a6fb47d 292 PRINTS PR00412 Epoxide hydrolase signature 61 76 1.1E-17 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK77_RS22510 065fe2fa4652a7eeb0eb3d721a6fb47d 292 PRINTS PR00412 Epoxide hydrolase signature 41 59 1.1E-17 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK77_RS22510 065fe2fa4652a7eeb0eb3d721a6fb47d 292 PRINTS PR00412 Epoxide hydrolase signature 262 284 1.1E-17 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK77_RS22510 065fe2fa4652a7eeb0eb3d721a6fb47d 292 PRINTS PR00412 Epoxide hydrolase signature 105 118 1.1E-17 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK77_RS09725 cdd57e68a8b3d1db0d6d98d58e09422f 642 Gene3D G3DSA:3.90.1310.10 183 282 5.1E-25 T 06-07-2017 CAK77_RS09725 cdd57e68a8b3d1db0d6d98d58e09422f 642 Gene3D G3DSA:3.40.710.10 283 623 4.8E-82 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK77_RS09725 cdd57e68a8b3d1db0d6d98d58e09422f 642 SUPERFAMILY SSF56601 276 629 2.22E-89 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK77_RS09725 cdd57e68a8b3d1db0d6d98d58e09422f 642 SUPERFAMILY SSF56519 73 111 1.07E-27 T 06-07-2017 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CAK77_RS09725 cdd57e68a8b3d1db0d6d98d58e09422f 642 SUPERFAMILY SSF56519 170 275 1.07E-27 T 06-07-2017 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CAK77_RS09725 cdd57e68a8b3d1db0d6d98d58e09422f 642 Pfam PF00905 Penicillin binding protein transpeptidase domain 302 617 3.3E-77 T 06-07-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CAK77_RS09725 cdd57e68a8b3d1db0d6d98d58e09422f 642 Pfam PF03717 Penicillin-binding Protein dimerisation domain 75 257 4.7E-11 T 06-07-2017 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CAK77_RS00880 31e63140662e4064c2bad0ffb0e3ff9a 286 Pfam PF00106 short chain dehydrogenase 2 190 2.8E-52 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS00880 31e63140662e4064c2bad0ffb0e3ff9a 286 SUPERFAMILY SSF51735 2 257 8.89E-65 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS00880 31e63140662e4064c2bad0ffb0e3ff9a 286 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 2.6E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS00880 31e63140662e4064c2bad0ffb0e3ff9a 286 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 2.6E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS00880 31e63140662e4064c2bad0ffb0e3ff9a 286 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 170 2.6E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS00880 31e63140662e4064c2bad0ffb0e3ff9a 286 Gene3D G3DSA:3.40.50.720 2 254 1.3E-67 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS00880 31e63140662e4064c2bad0ffb0e3ff9a 286 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2 187 0.0027 T 06-07-2017 CAK77_RS00880 31e63140662e4064c2bad0ffb0e3ff9a 286 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 1.6E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS00880 31e63140662e4064c2bad0ffb0e3ff9a 286 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 1.6E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS00880 31e63140662e4064c2bad0ffb0e3ff9a 286 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 1.6E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS00880 31e63140662e4064c2bad0ffb0e3ff9a 286 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 1.6E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS00880 31e63140662e4064c2bad0ffb0e3ff9a 286 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 1.6E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS01700 4b0ea174b85764a3f621f02dab224c74 80 ProSitePatterns PS01143 Ribosomal protein L31 signature. 48 69 - T 06-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS01700 4b0ea174b85764a3f621f02dab224c74 80 SUPERFAMILY SSF143800 1 78 7.06E-22 T 06-07-2017 CAK77_RS01700 4b0ea174b85764a3f621f02dab224c74 80 Pfam PF01197 Ribosomal protein L31 1 78 2.4E-30 T 06-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS01700 4b0ea174b85764a3f621f02dab224c74 80 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 79 4.5E-21 T 06-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS01700 4b0ea174b85764a3f621f02dab224c74 80 PRINTS PR01249 Ribosomal protein L31 signature 59 77 3.6E-16 T 06-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS01700 4b0ea174b85764a3f621f02dab224c74 80 PRINTS PR01249 Ribosomal protein L31 signature 2 19 3.6E-16 T 06-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS01700 4b0ea174b85764a3f621f02dab224c74 80 PRINTS PR01249 Ribosomal protein L31 signature 44 59 3.6E-16 T 06-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS01700 4b0ea174b85764a3f621f02dab224c74 80 Hamap MF_00502 50S ribosomal protein L31 type B [rpmE2]. 1 80 24.306 T 06-07-2017 IPR027493 Ribosomal protein L31 type B GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS11155 32be809aca77ed77a254b50e55ac5cf9 151 SMART SM00347 29 129 6.0E-15 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK77_RS11155 32be809aca77ed77a254b50e55ac5cf9 151 SUPERFAMILY SSF46785 12 141 8.67E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS11155 32be809aca77ed77a254b50e55ac5cf9 151 Gene3D G3DSA:1.10.10.10 13 141 9.8E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS11155 32be809aca77ed77a254b50e55ac5cf9 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 85 7.9E-9 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK77_RS11155 32be809aca77ed77a254b50e55ac5cf9 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 53 69 7.9E-9 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK77_RS11155 32be809aca77ed77a254b50e55ac5cf9 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 119 139 7.9E-9 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK77_RS11155 32be809aca77ed77a254b50e55ac5cf9 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 105 7.9E-9 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK77_RS11155 32be809aca77ed77a254b50e55ac5cf9 151 Pfam PF01047 MarR family 40 93 2.4E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK77_RS13345 6c55e7ac74b268d1aa7cafa0444cd805 336 SMART SM00327 97 273 2.6E-24 T 06-07-2017 IPR002035 von Willebrand factor, type A CAK77_RS13345 6c55e7ac74b268d1aa7cafa0444cd805 336 Pfam PF07584 Aerotolerance regulator N-terminal 13 87 2.9E-6 T 06-07-2017 IPR024163 Aerotolerance regulator, N-terminal CAK77_RS13345 6c55e7ac74b268d1aa7cafa0444cd805 336 Gene3D G3DSA:3.40.50.410 98 299 7.9E-22 T 06-07-2017 IPR002035 von Willebrand factor, type A CAK77_RS13345 6c55e7ac74b268d1aa7cafa0444cd805 336 SUPERFAMILY SSF53300 95 298 3.89E-29 T 06-07-2017 IPR002035 von Willebrand factor, type A CAK77_RS13345 6c55e7ac74b268d1aa7cafa0444cd805 336 Pfam PF13519 von Willebrand factor type A domain 100 212 1.7E-18 T 06-07-2017 IPR002035 von Willebrand factor, type A CAK77_RS03905 1f007f94296d8bc08ae096515f18424f 357 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 10 73 1.9E-5 T 06-07-2017 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAK77_RS03905 1f007f94296d8bc08ae096515f18424f 357 Gene3D G3DSA:3.40.50.720 1 161 1.8E-23 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS03905 1f007f94296d8bc08ae096515f18424f 357 SUPERFAMILY SSF51735 4 104 4.22E-12 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS10720 b154a837df2d1ddb11132c66f801882e 1207 TIGRFAM TIGR02257 cobalto_cobN: cobaltochelatase, CobN subunit 48 1202 0.0 T 06-07-2017 IPR011953 Cobaltochelatase, CobN subunit GO:0009236|GO:0051116 CAK77_RS10720 b154a837df2d1ddb11132c66f801882e 1207 Pfam PF02514 CobN/Magnesium Chelatase 102 1189 0.0 T 06-07-2017 IPR003672 CobN/magnesium chelatase GO:0009058 CAK77_RS24215 9d7798dfa079d76b948b10e22869762b 951 Gene3D G3DSA:1.10.730.10 748 887 9.6E-34 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK77_RS24215 9d7798dfa079d76b948b10e22869762b 951 Pfam PF08264 Anticodon-binding domain of tRNA 800 913 1.7E-14 T 06-07-2017 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CAK77_RS24215 9d7798dfa079d76b948b10e22869762b 951 SUPERFAMILY SSF50677 317 501 9.31E-43 T 06-07-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CAK77_RS24215 9d7798dfa079d76b948b10e22869762b 951 Gene3D G3DSA:3.90.740.10 305 546 1.2E-56 T 06-07-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CAK77_RS24215 9d7798dfa079d76b948b10e22869762b 951 PRINTS PR00985 Leucyl-tRNA synthetase signature 638 660 1.1E-53 T 06-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CAK77_RS24215 9d7798dfa079d76b948b10e22869762b 951 PRINTS PR00985 Leucyl-tRNA synthetase signature 262 275 1.1E-53 T 06-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CAK77_RS24215 9d7798dfa079d76b948b10e22869762b 951 PRINTS PR00985 Leucyl-tRNA synthetase signature 229 245 1.1E-53 T 06-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CAK77_RS24215 9d7798dfa079d76b948b10e22869762b 951 PRINTS PR00985 Leucyl-tRNA synthetase signature 291 310 1.1E-53 T 06-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CAK77_RS24215 9d7798dfa079d76b948b10e22869762b 951 PRINTS PR00985 Leucyl-tRNA synthetase signature 156 173 1.1E-53 T 06-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CAK77_RS24215 9d7798dfa079d76b948b10e22869762b 951 PRINTS PR00985 Leucyl-tRNA synthetase signature 586 604 1.1E-53 T 06-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CAK77_RS24215 9d7798dfa079d76b948b10e22869762b 951 PRINTS PR00985 Leucyl-tRNA synthetase signature 671 681 1.1E-53 T 06-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CAK77_RS24215 9d7798dfa079d76b948b10e22869762b 951 SUPERFAMILY SSF47323 764 951 8.04E-31 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK77_RS24215 9d7798dfa079d76b948b10e22869762b 951 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 21 951 21.385 T 06-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CAK77_RS24215 9d7798dfa079d76b948b10e22869762b 951 SUPERFAMILY SSF52374 224 302 5.63E-103 T 06-07-2017 CAK77_RS24215 9d7798dfa079d76b948b10e22869762b 951 SUPERFAMILY SSF52374 26 176 5.63E-103 T 06-07-2017 CAK77_RS24215 9d7798dfa079d76b948b10e22869762b 951 SUPERFAMILY SSF52374 502 769 5.63E-103 T 06-07-2017 CAK77_RS24215 9d7798dfa079d76b948b10e22869762b 951 Pfam PF09334 tRNA synthetases class I (M) 66 174 1.7E-12 T 06-07-2017 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK77_RS24215 9d7798dfa079d76b948b10e22869762b 951 Gene3D G3DSA:3.40.50.620 720 747 1.2E-113 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS24215 9d7798dfa079d76b948b10e22869762b 951 Gene3D G3DSA:3.40.50.620 26 175 1.2E-113 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS24215 9d7798dfa079d76b948b10e22869762b 951 Gene3D G3DSA:3.40.50.620 589 687 1.2E-113 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS24215 9d7798dfa079d76b948b10e22869762b 951 Gene3D G3DSA:3.40.50.620 223 304 1.2E-113 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS24215 9d7798dfa079d76b948b10e22869762b 951 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 72 82 - T 06-07-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAK77_RS24215 9d7798dfa079d76b948b10e22869762b 951 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 224 951 6.7E-211 T 06-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CAK77_RS24215 9d7798dfa079d76b948b10e22869762b 951 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 297 489 1.9E-58 T 06-07-2017 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 CAK77_RS14375 e455bc701060c8a3a9933f780c1959a0 291 SUPERFAMILY SSF52402 158 290 8.37E-28 T 06-07-2017 CAK77_RS14375 e455bc701060c8a3a9933f780c1959a0 291 SUPERFAMILY SSF52402 10 153 9.21E-30 T 06-07-2017 CAK77_RS14375 e455bc701060c8a3a9933f780c1959a0 291 Gene3D G3DSA:3.40.50.620 157 289 9.2E-33 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS14375 e455bc701060c8a3a9933f780c1959a0 291 Pfam PF00582 Universal stress protein family 159 289 8.7E-22 T 06-07-2017 IPR006016 UspA GO:0006950 CAK77_RS14375 e455bc701060c8a3a9933f780c1959a0 291 Pfam PF00582 Universal stress protein family 10 148 1.9E-21 T 06-07-2017 IPR006016 UspA GO:0006950 CAK77_RS14375 e455bc701060c8a3a9933f780c1959a0 291 PRINTS PR01438 Universal stress protein signature 249 261 3.7E-15 T 06-07-2017 IPR006015 Universal stress protein A CAK77_RS14375 e455bc701060c8a3a9933f780c1959a0 291 PRINTS PR01438 Universal stress protein signature 267 289 3.7E-15 T 06-07-2017 IPR006015 Universal stress protein A CAK77_RS14375 e455bc701060c8a3a9933f780c1959a0 291 PRINTS PR01438 Universal stress protein signature 156 174 3.7E-15 T 06-07-2017 IPR006015 Universal stress protein A CAK77_RS14375 e455bc701060c8a3a9933f780c1959a0 291 Gene3D G3DSA:3.40.50.620 10 149 1.2E-30 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS14845 858d670c51aa9ac9185c1aaf9908d564 231 Gene3D G3DSA:3.30.70.1100 133 230 4.8E-41 T 06-07-2017 CAK77_RS14845 858d670c51aa9ac9185c1aaf9908d564 231 Gene3D G3DSA:3.30.70.1030 15 132 2.5E-22 T 06-07-2017 CAK77_RS14845 858d670c51aa9ac9185c1aaf9908d564 231 Pfam PF06778 Chlorite dismutase 32 220 4.8E-71 T 06-07-2017 IPR010644 Putative heme-dependent peroxidase/Chlorite dismutase CAK77_RS14845 858d670c51aa9ac9185c1aaf9908d564 231 SUPERFAMILY SSF54909 5 230 2.95E-76 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAK77_RS00510 37bbe3714f3eb0ea4fab272b74f4aca2 278 SUPERFAMILY SSF52821 3 143 1.26E-40 T 06-07-2017 IPR001763 Rhodanese-like domain CAK77_RS00510 37bbe3714f3eb0ea4fab272b74f4aca2 278 SUPERFAMILY SSF52821 155 276 3.93E-33 T 06-07-2017 IPR001763 Rhodanese-like domain CAK77_RS00510 37bbe3714f3eb0ea4fab272b74f4aca2 278 SMART SM00450 3 128 3.6E-25 T 06-07-2017 IPR001763 Rhodanese-like domain CAK77_RS00510 37bbe3714f3eb0ea4fab272b74f4aca2 278 SMART SM00450 152 269 2.2E-14 T 06-07-2017 IPR001763 Rhodanese-like domain CAK77_RS00510 37bbe3714f3eb0ea4fab272b74f4aca2 278 Pfam PF00581 Rhodanese-like domain 6 124 6.9E-19 T 06-07-2017 IPR001763 Rhodanese-like domain CAK77_RS00510 37bbe3714f3eb0ea4fab272b74f4aca2 278 Pfam PF00581 Rhodanese-like domain 157 265 8.1E-11 T 06-07-2017 IPR001763 Rhodanese-like domain CAK77_RS00510 37bbe3714f3eb0ea4fab272b74f4aca2 278 ProSitePatterns PS00683 Rhodanese C-terminal signature. 253 263 - T 06-07-2017 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 CAK77_RS00510 37bbe3714f3eb0ea4fab272b74f4aca2 278 ProSitePatterns PS00380 Rhodanese signature 1. 35 46 - T 06-07-2017 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 CAK77_RS00510 37bbe3714f3eb0ea4fab272b74f4aca2 278 Gene3D G3DSA:3.40.250.10 152 276 1.6E-37 T 06-07-2017 IPR001763 Rhodanese-like domain CAK77_RS00510 37bbe3714f3eb0ea4fab272b74f4aca2 278 Gene3D G3DSA:3.40.250.10 1 144 3.1E-48 T 06-07-2017 IPR001763 Rhodanese-like domain CAK77_RS18350 d730922f0d1fed37bb3202b7e5f3f5e4 273 SUPERFAMILY SSF56219 6 272 5.1E-67 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase CAK77_RS18350 d730922f0d1fed37bb3202b7e5f3f5e4 273 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 8 271 5.3E-60 T 06-07-2017 CAK77_RS18350 d730922f0d1fed37bb3202b7e5f3f5e4 273 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 8 272 9.3E-65 T 06-07-2017 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 CAK77_RS18350 d730922f0d1fed37bb3202b7e5f3f5e4 273 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 10 265 6.6E-27 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase CAK77_RS18350 d730922f0d1fed37bb3202b7e5f3f5e4 273 Gene3D G3DSA:3.60.10.10 6 272 6.4E-86 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase CAK77_RS16665 fba7e6659e2cb494b1134aec62f13db8 206 Pfam PF00881 Nitroreductase family 7 173 3.2E-24 T 06-07-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 CAK77_RS16665 fba7e6659e2cb494b1134aec62f13db8 206 TIGRFAM TIGR02476 BluB: 5,6-dimethylbenzimidazole synthase 3 198 4.3E-63 T 06-07-2017 IPR012825 5,6-dimethylbenzimidazole synthase BluB KEGG: 00740+1.13.11.79|MetaCyc: PWY-5508|MetaCyc: PWY-5523 CAK77_RS16665 fba7e6659e2cb494b1134aec62f13db8 206 Gene3D G3DSA:3.40.109.10 1 204 1.9E-41 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CAK77_RS16665 fba7e6659e2cb494b1134aec62f13db8 206 SUPERFAMILY SSF55469 1 204 7.85E-45 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CAK77_RS13725 c50ea222833304a7e4a7d04a02ee61d6 513 Gene3D G3DSA:1.20.1250.20 304 439 7.5E-12 T 06-07-2017 CAK77_RS13725 c50ea222833304a7e4a7d04a02ee61d6 513 Gene3D G3DSA:1.20.1250.20 476 508 7.5E-12 T 06-07-2017 CAK77_RS13725 c50ea222833304a7e4a7d04a02ee61d6 513 Gene3D G3DSA:1.20.1250.20 21 207 2.7E-26 T 06-07-2017 CAK77_RS13725 c50ea222833304a7e4a7d04a02ee61d6 513 ProSitePatterns PS00216 Sugar transport proteins signature 1. 77 93 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CAK77_RS13725 c50ea222833304a7e4a7d04a02ee61d6 513 Pfam PF07690 Major Facilitator Superfamily 26 432 2.9E-37 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK77_RS13725 c50ea222833304a7e4a7d04a02ee61d6 513 SUPERFAMILY SSF103473 12 205 2.22E-48 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK77_RS13725 c50ea222833304a7e4a7d04a02ee61d6 513 SUPERFAMILY SSF103473 479 508 2.22E-48 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK77_RS13725 c50ea222833304a7e4a7d04a02ee61d6 513 SUPERFAMILY SSF103473 260 442 2.22E-48 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK77_RS07575 44de2dc2cb929cfbd02a1e56cf7eb6c3 151 Pfam PF01575 MaoC like domain 20 129 2.9E-24 T 06-07-2017 IPR002539 MaoC-like domain CAK77_RS07575 44de2dc2cb929cfbd02a1e56cf7eb6c3 151 SUPERFAMILY SSF54637 19 148 2.73E-33 T 06-07-2017 IPR029069 HotDog domain CAK77_RS07575 44de2dc2cb929cfbd02a1e56cf7eb6c3 151 Gene3D G3DSA:3.10.129.10 19 149 6.1E-31 T 06-07-2017 IPR029069 HotDog domain CAK77_RS03645 a220686b9ad0bbfafdf9d7315390f5c6 145 Pfam PF13564 DoxX-like family 34 129 4.3E-11 T 06-07-2017 IPR032808 DoxX family CAK77_RS08685 983b02ba632367999107fd8e4220274e 340 Gene3D G3DSA:3.40.50.1100 110 337 2.1E-72 T 06-07-2017 CAK77_RS08685 983b02ba632367999107fd8e4220274e 340 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 13 324 9.3E-44 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAK77_RS08685 983b02ba632367999107fd8e4220274e 340 TIGRFAM TIGR01274 ACC_deam: 1-aminocyclopropane-1-carboxylate deaminase 3 338 2.3E-158 T 06-07-2017 IPR005965 1-aminocyclopropane-1-carboxylate deaminase GO:0008660|GO:0009310|GO:0030170 KEGG: 00270+3.5.99.7 CAK77_RS08685 983b02ba632367999107fd8e4220274e 340 PIRSF PIRSF006278 2 340 1.5E-114 T 06-07-2017 IPR027278 1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase CAK77_RS08685 983b02ba632367999107fd8e4220274e 340 SUPERFAMILY SSF53686 5 338 8.35E-92 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAK77_RS13925 41d3b7bfbc0b052e0eba7e67999292a3 337 SUPERFAMILY SSF47240 25 231 1.15E-5 T 06-07-2017 IPR009078 Ferritin-like superfamily CAK77_RS13925 41d3b7bfbc0b052e0eba7e67999292a3 337 Pfam PF11583 P-aminobenzoate N-oxygenase AurF 14 298 2.1E-105 T 06-07-2017 IPR025859 P-aminobenzoate N-oxygenase AurF CAK77_RS03700 50e822106e16dc5280349b7adaa5ac2f 296 SUPERFAMILY SSF51735 5 227 3.36E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS03700 50e822106e16dc5280349b7adaa5ac2f 296 Pfam PF00106 short chain dehydrogenase 5 130 4.6E-14 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS03700 50e822106e16dc5280349b7adaa5ac2f 296 Gene3D G3DSA:3.40.50.720 5 213 4.5E-31 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS03700 50e822106e16dc5280349b7adaa5ac2f 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 166 2.7E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS03700 50e822106e16dc5280349b7adaa5ac2f 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 2.7E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS03700 50e822106e16dc5280349b7adaa5ac2f 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 2.7E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS11755 13a641249b7428d688b1705e9b7f7a72 251 Pfam PF14032 PknH-like extracellular domain 64 245 7.7E-32 T 06-07-2017 IPR026954 PknH-like extracellular domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 CAK77_RS23380 b5aee537e69ec6e1a733f19f51633fb4 426 Gene3D G3DSA:3.40.50.2000 1 258 1.9E-56 T 06-07-2017 CAK77_RS23380 b5aee537e69ec6e1a733f19f51633fb4 426 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 3 91 1.6E-9 T 06-07-2017 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CAK77_RS23380 b5aee537e69ec6e1a733f19f51633fb4 426 SUPERFAMILY SSF53756 1 423 3.77E-86 T 06-07-2017 CAK77_RS23380 b5aee537e69ec6e1a733f19f51633fb4 426 Gene3D G3DSA:3.40.50.2000 259 402 1.7E-49 T 06-07-2017 CAK77_RS06935 93fdba9d16336f4e81a501d48e170a31 277 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 173 269 6.4E-12 T 06-07-2017 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 CAK77_RS06935 93fdba9d16336f4e81a501d48e170a31 277 Gene3D G3DSA:3.40.190.10 22 126 1.4E-14 T 06-07-2017 CAK77_RS06935 93fdba9d16336f4e81a501d48e170a31 277 Gene3D G3DSA:3.40.190.10 225 274 1.4E-14 T 06-07-2017 CAK77_RS06935 93fdba9d16336f4e81a501d48e170a31 277 SUPERFAMILY SSF53850 22 273 5.37E-22 T 06-07-2017 CAK77_RS11830 57e9681f789f0b134db04f8cb3e9cedb 344 Pfam PF07174 Fibronectin-attachment protein (FAP) 11 277 2.2E-78 T 06-07-2017 IPR010801 Fibronectin-attachment GO:0005576|GO:0050840 CAK77_RS11830 57e9681f789f0b134db04f8cb3e9cedb 344 PRINTS PR01217 Proline rich extensin signature 74 90 3.4E-9 T 06-07-2017 CAK77_RS11830 57e9681f789f0b134db04f8cb3e9cedb 344 PRINTS PR01217 Proline rich extensin signature 97 109 3.4E-9 T 06-07-2017 CAK77_RS11830 57e9681f789f0b134db04f8cb3e9cedb 344 PRINTS PR01217 Proline rich extensin signature 261 286 3.4E-9 T 06-07-2017 CAK77_RS11830 57e9681f789f0b134db04f8cb3e9cedb 344 PRINTS PR01217 Proline rich extensin signature 60 72 3.4E-9 T 06-07-2017 CAK77_RS02755 6d1b7aafbc421fa90ef1352855e8e97c 272 Pfam PF05019 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 54 234 6.5E-18 T 06-07-2017 IPR007715 Ubiquinone biosynthesis protein Coq4 GO:0006744 CAK77_RS02345 107668ebd294918e1e4dc4b68082431b 231 Gene3D G3DSA:2.40.10.10 37 116 5.9E-7 T 06-07-2017 CAK77_RS02345 107668ebd294918e1e4dc4b68082431b 231 SUPERFAMILY SSF50494 40 198 1.08E-19 T 06-07-2017 IPR009003 Peptidase S1, PA clan CAK77_RS02345 107668ebd294918e1e4dc4b68082431b 231 Gene3D G3DSA:2.40.10.10 127 193 1.2E-9 T 06-07-2017 CAK77_RS14340 f1581a79a5b4aad4e316eb7a05e7dcc3 301 Pfam PF00582 Universal stress protein family 156 293 1.3E-29 T 06-07-2017 IPR006016 UspA GO:0006950 CAK77_RS14340 f1581a79a5b4aad4e316eb7a05e7dcc3 301 Pfam PF00582 Universal stress protein family 10 146 4.9E-21 T 06-07-2017 IPR006016 UspA GO:0006950 CAK77_RS14340 f1581a79a5b4aad4e316eb7a05e7dcc3 301 Gene3D G3DSA:3.40.50.620 141 293 3.6E-42 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS14340 f1581a79a5b4aad4e316eb7a05e7dcc3 301 PRINTS PR01438 Universal stress protein signature 271 293 5.0E-15 T 06-07-2017 IPR006015 Universal stress protein A CAK77_RS14340 f1581a79a5b4aad4e316eb7a05e7dcc3 301 PRINTS PR01438 Universal stress protein signature 7 25 5.0E-15 T 06-07-2017 IPR006015 Universal stress protein A CAK77_RS14340 f1581a79a5b4aad4e316eb7a05e7dcc3 301 PRINTS PR01438 Universal stress protein signature 253 265 5.0E-15 T 06-07-2017 IPR006015 Universal stress protein A CAK77_RS14340 f1581a79a5b4aad4e316eb7a05e7dcc3 301 SUPERFAMILY SSF52402 10 149 1.59E-25 T 06-07-2017 CAK77_RS14340 f1581a79a5b4aad4e316eb7a05e7dcc3 301 SUPERFAMILY SSF52402 155 297 7.62E-35 T 06-07-2017 CAK77_RS14340 f1581a79a5b4aad4e316eb7a05e7dcc3 301 Gene3D G3DSA:3.40.50.620 10 140 5.2E-27 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS04940 19d49d9656f437a0b1c6d9a0551af0b7 481 Pfam PF01580 FtsK/SpoIIIE family 217 397 4.4E-16 T 06-07-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CAK77_RS04940 19d49d9656f437a0b1c6d9a0551af0b7 481 SMART SM00382 225 393 0.001 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS04940 19d49d9656f437a0b1c6d9a0551af0b7 481 SUPERFAMILY SSF52540 195 447 4.13E-22 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS04940 19d49d9656f437a0b1c6d9a0551af0b7 481 Gene3D G3DSA:3.40.50.300 208 446 8.0E-19 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS09840 8b08d646004e84908973ba813d330a4c 160 Gene3D G3DSA:1.10.1200.10 5 64 2.9E-9 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS09840 8b08d646004e84908973ba813d330a4c 160 SUPERFAMILY SSF47336 6 65 1.96E-9 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS09840 8b08d646004e84908973ba813d330a4c 160 Pfam PF00550 Phosphopantetheine attachment site 14 65 8.6E-9 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAK77_RS15715 c20a479b17a922bf0cb093cefd25acbd 148 SUPERFAMILY SSF55729 10 144 2.66E-26 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS15715 c20a479b17a922bf0cb093cefd25acbd 148 Gene3D G3DSA:3.40.630.30 10 143 5.9E-35 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS15715 c20a479b17a922bf0cb093cefd25acbd 148 Pfam PF13673 Acetyltransferase (GNAT) domain 44 143 1.3E-12 T 06-07-2017 IPR000182 GNAT domain GO:0008080 CAK77_RS10515 980be1e7b25a5a283bb81c4916d446ee 200 ProDom PD033474 ANTIGEN PRECURSOR SIGNAL LIPOPROTEIN LOW WEIGHT MOLECULAR LPPK MEMBRANE PALMITATE 69 170 3.0E-24 T 06-07-2017 IPR020235 Low molecular weight antigen MTB12 CAK77_RS02330 093acf1153f3dc0d17ef3259808c8db6 421 Pfam PF13365 Trypsin-like peptidase domain 221 357 7.8E-22 T 06-07-2017 CAK77_RS02330 093acf1153f3dc0d17ef3259808c8db6 421 Gene3D G3DSA:2.40.10.10 196 277 2.3E-14 T 06-07-2017 CAK77_RS02330 093acf1153f3dc0d17ef3259808c8db6 421 PRINTS PR00834 HtrA/DegQ protease family signature 229 241 1.1E-8 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAK77_RS02330 093acf1153f3dc0d17ef3259808c8db6 421 PRINTS PR00834 HtrA/DegQ protease family signature 249 269 1.1E-8 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAK77_RS02330 093acf1153f3dc0d17ef3259808c8db6 421 PRINTS PR00834 HtrA/DegQ protease family signature 288 312 1.1E-8 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAK77_RS02330 093acf1153f3dc0d17ef3259808c8db6 421 PRINTS PR00834 HtrA/DegQ protease family signature 328 345 1.1E-8 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAK77_RS02330 093acf1153f3dc0d17ef3259808c8db6 421 Gene3D G3DSA:2.40.10.10 278 382 5.2E-16 T 06-07-2017 CAK77_RS02330 093acf1153f3dc0d17ef3259808c8db6 421 Pfam PF02674 Colicin V production protein 9 150 1.2E-15 T 06-07-2017 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 CAK77_RS02330 093acf1153f3dc0d17ef3259808c8db6 421 SUPERFAMILY SSF50494 198 381 3.49E-35 T 06-07-2017 IPR009003 Peptidase S1, PA clan CAK77_RS18245 9dda18fe34f27fab4e8981072601f2f4 108 Pfam PF10824 Excreted virulence factor EspC, type VII ESX diderm 1 100 2.1E-5 T 06-07-2017 IPR022536 ESX-1 secretion-associated protein EspC CAK77_RS18135 1c1a4103fec6e0e98a38f614d64a383f 136 Gene3D G3DSA:3.90.1010.10 2 134 1.3E-33 T 06-07-2017 CAK77_RS18135 1c1a4103fec6e0e98a38f614d64a383f 136 Pfam PF02657 Fe-S metabolism associated domain 12 133 6.6E-30 T 06-07-2017 IPR003808 Fe-S metabolism associated domain, SufE-like CAK77_RS18135 1c1a4103fec6e0e98a38f614d64a383f 136 SUPERFAMILY SSF82649 3 134 1.99E-28 T 06-07-2017 CAK77_RS21085 dba571b03ec19fb4d04eb01d36403bd1 449 Gene3D G3DSA:3.40.640.10 78 326 1.1E-82 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK77_RS21085 dba571b03ec19fb4d04eb01d36403bd1 449 Gene3D G3DSA:3.90.1150.10 327 444 9.8E-40 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK77_RS21085 dba571b03ec19fb4d04eb01d36403bd1 449 TIGRFAM TIGR00700 GABAtrnsam: 4-aminobutyrate transaminase 29 443 3.0E-179 T 06-07-2017 IPR004632 4-aminobutyrate aminotransferase, bacterial GO:0003867|GO:0009448 CAK77_RS21085 dba571b03ec19fb4d04eb01d36403bd1 449 SUPERFAMILY SSF53383 41 442 1.46E-123 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK77_RS21085 dba571b03ec19fb4d04eb01d36403bd1 449 Pfam PF00202 Aminotransferase class-III 43 442 2.8E-125 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAK77_RS21085 dba571b03ec19fb4d04eb01d36403bd1 449 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 258 295 - T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAK77_RS19010 b88d3ce8e1a9a3fbe954c9f735c11079 327 Pfam PF01083 Cutinase 40 224 3.0E-44 T 06-07-2017 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 CAK77_RS19010 b88d3ce8e1a9a3fbe954c9f735c11079 327 SMART SM01110 38 225 5.8E-73 T 06-07-2017 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 CAK77_RS19010 b88d3ce8e1a9a3fbe954c9f735c11079 327 Gene3D G3DSA:3.40.50.1820 31 228 8.3E-51 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS19010 b88d3ce8e1a9a3fbe954c9f735c11079 327 SUPERFAMILY SSF53474 34 226 3.25E-33 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS22735 ce744a5f7362cdcb8bf181801e0d8399 510 Pfam PF02470 MlaD protein 46 124 6.1E-8 T 06-07-2017 IPR003399 Mce/MlaD CAK77_RS22735 ce744a5f7362cdcb8bf181801e0d8399 510 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 178 371 3.0E-12 T 06-07-2017 IPR024516 Mammalian cell entry, C-terminal CAK77_RS23865 afc357c63e725e66559f4672798ed0a1 277 Gene3D G3DSA:3.40.50.720 30 257 2.2E-48 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS23865 afc357c63e725e66559f4672798ed0a1 277 SUPERFAMILY SSF51735 31 253 1.62E-48 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS23865 afc357c63e725e66559f4672798ed0a1 277 Pfam PF00106 short chain dehydrogenase 36 221 4.5E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS23865 afc357c63e725e66559f4672798ed0a1 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 198 3.6E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS23865 afc357c63e725e66559f4672798ed0a1 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 103 114 3.6E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS23865 afc357c63e725e66559f4672798ed0a1 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 168 3.6E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS23865 afc357c63e725e66559f4672798ed0a1 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 36 53 3.6E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS23865 afc357c63e725e66559f4672798ed0a1 277 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 179 198 1.1E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS23865 afc357c63e725e66559f4672798ed0a1 277 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 166 1.1E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS23865 afc357c63e725e66559f4672798ed0a1 277 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 103 114 1.1E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS11180 2504c4346c4771d7291967d0b23ec82a 395 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 4 180 3.3E-45 T 06-07-2017 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24 CAK77_RS11180 2504c4346c4771d7291967d0b23ec82a 395 SUPERFAMILY SSF52540 1 194 6.68E-37 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS11180 2504c4346c4771d7291967d0b23ec82a 395 Gene3D G3DSA:3.30.460.10 211 389 3.8E-50 T 06-07-2017 CAK77_RS11180 2504c4346c4771d7291967d0b23ec82a 395 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 1 196 24.9 T 06-07-2017 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24 CAK77_RS11180 2504c4346c4771d7291967d0b23ec82a 395 Pfam PF01121 Dephospho-CoA kinase 4 179 7.6E-60 T 06-07-2017 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24 CAK77_RS11180 2504c4346c4771d7291967d0b23ec82a 395 Gene3D G3DSA:3.40.50.300 1 192 1.6E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS11180 2504c4346c4771d7291967d0b23ec82a 395 SUPERFAMILY SSF81301 212 389 1.8E-41 T 06-07-2017 CAK77_RS11180 2504c4346c4771d7291967d0b23ec82a 395 Pfam PF04229 GrpB protein 212 382 2.5E-41 T 06-07-2017 IPR007344 GrpB/Dephospho-CoA kinase CAK77_RS21515 116e45446393d061927b3eacdf7a4afe 311 Pfam PF00296 Luciferase-like monooxygenase 8 250 1.0E-50 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS21515 116e45446393d061927b3eacdf7a4afe 311 SUPERFAMILY SSF51679 1 310 2.22E-72 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS21515 116e45446393d061927b3eacdf7a4afe 311 Gene3D G3DSA:3.20.20.30 8 310 2.2E-78 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS21515 116e45446393d061927b3eacdf7a4afe 311 TIGRFAM TIGR03560 F420_Rv1855c: probable F420-dependent oxidoreductase, Rv1855c family 2 231 4.3E-90 T 06-07-2017 IPR019952 F420-dependent oxidoreductase-predicted, Rv1855c CAK77_RS14370 13e9ae0056f563a786e335bc472d9e24 268 Gene3D G3DSA:3.40.50.620 8 144 4.7E-27 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS14370 13e9ae0056f563a786e335bc472d9e24 268 PRINTS PR01438 Universal stress protein signature 7 25 1.3E-10 T 06-07-2017 IPR006015 Universal stress protein A CAK77_RS14370 13e9ae0056f563a786e335bc472d9e24 268 PRINTS PR01438 Universal stress protein signature 101 113 1.3E-10 T 06-07-2017 IPR006015 Universal stress protein A CAK77_RS14370 13e9ae0056f563a786e335bc472d9e24 268 PRINTS PR01438 Universal stress protein signature 119 141 1.3E-10 T 06-07-2017 IPR006015 Universal stress protein A CAK77_RS14370 13e9ae0056f563a786e335bc472d9e24 268 Pfam PF00582 Universal stress protein family 10 141 2.5E-21 T 06-07-2017 IPR006016 UspA GO:0006950 CAK77_RS14370 13e9ae0056f563a786e335bc472d9e24 268 SUPERFAMILY SSF52402 9 147 2.51E-26 T 06-07-2017 CAK77_RS08305 613bf0626db81578099654dd24e6c445 472 SUPERFAMILY SSF51905 11 209 1.3E-28 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS08305 613bf0626db81578099654dd24e6c445 472 SUPERFAMILY SSF51905 309 388 1.3E-28 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS08305 613bf0626db81578099654dd24e6c445 472 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 318 333 2.7E-5 T 06-07-2017 CAK77_RS08305 613bf0626db81578099654dd24e6c445 472 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 333 349 2.7E-5 T 06-07-2017 CAK77_RS08305 613bf0626db81578099654dd24e6c445 472 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 11 33 2.7E-5 T 06-07-2017 CAK77_RS08305 613bf0626db81578099654dd24e6c445 472 Pfam PF01494 FAD binding domain 13 350 1.1E-8 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 CAK77_RS08305 613bf0626db81578099654dd24e6c445 472 Gene3D G3DSA:3.50.50.60 316 353 1.6E-21 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS08305 613bf0626db81578099654dd24e6c445 472 Gene3D G3DSA:3.50.50.60 13 205 1.6E-21 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS15945 9d74f84030c47dca4a2a575b69c3c281 276 Gene3D G3DSA:3.40.50.80 121 269 5.1E-46 T 06-07-2017 CAK77_RS15945 9d74f84030c47dca4a2a575b69c3c281 276 Pfam PF08021 Siderophore-interacting FAD-binding domain 9 117 9.9E-29 T 06-07-2017 IPR013113 FAD-binding 9, siderophore-interacting CAK77_RS15945 9d74f84030c47dca4a2a575b69c3c281 276 SUPERFAMILY SSF63380 5 122 8.13E-9 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CAK77_RS15945 9d74f84030c47dca4a2a575b69c3c281 276 Gene3D G3DSA:2.40.30.10 3 117 3.8E-29 T 06-07-2017 CAK77_RS15945 9d74f84030c47dca4a2a575b69c3c281 276 Pfam PF04954 Siderophore-interacting protein 126 254 1.3E-32 T 06-07-2017 IPR007037 Siderophore-interacting protein CAK77_RS20275 3c0dfe34cc3fe520bc5c4416f7a15b0c 228 Pfam PF00486 Transcriptional regulatory protein, C terminal 150 226 1.4E-27 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAK77_RS20275 3c0dfe34cc3fe520bc5c4416f7a15b0c 228 Gene3D G3DSA:3.40.50.2300 1 124 8.1E-39 T 06-07-2017 CAK77_RS20275 3c0dfe34cc3fe520bc5c4416f7a15b0c 228 SMART SM00448 2 112 1.4E-42 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK77_RS20275 3c0dfe34cc3fe520bc5c4416f7a15b0c 228 SMART SM00862 150 226 2.6E-30 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAK77_RS20275 3c0dfe34cc3fe520bc5c4416f7a15b0c 228 Pfam PF00072 Response regulator receiver domain 4 113 7.4E-27 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK77_RS20275 3c0dfe34cc3fe520bc5c4416f7a15b0c 228 SUPERFAMILY SSF46894 127 227 1.59E-32 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAK77_RS20275 3c0dfe34cc3fe520bc5c4416f7a15b0c 228 SUPERFAMILY SSF52172 2 120 2.42E-39 T 06-07-2017 IPR011006 CheY-like superfamily CAK77_RS20275 3c0dfe34cc3fe520bc5c4416f7a15b0c 228 Gene3D G3DSA:1.10.10.10 129 227 1.9E-36 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS11660 da83e932310feff7f133e4ca6bd0c717 131 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 3 128 5.5E-44 T 06-07-2017 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 CAK77_RS11660 da83e932310feff7f133e4ca6bd0c717 131 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 5 131 28.747 T 06-07-2017 IPR002930 Glycine cleavage system H-protein CAK77_RS11660 da83e932310feff7f133e4ca6bd0c717 131 SUPERFAMILY SSF51230 4 127 5.5E-37 T 06-07-2017 IPR011053 Single hybrid motif CAK77_RS11660 da83e932310feff7f133e4ca6bd0c717 131 Gene3D G3DSA:2.40.50.100 7 126 2.1E-43 T 06-07-2017 CAK77_RS11660 da83e932310feff7f133e4ca6bd0c717 131 Pfam PF01597 Glycine cleavage H-protein 8 117 3.4E-38 T 06-07-2017 IPR002930 Glycine cleavage system H-protein CAK77_RS03315 3089e79ed7e9871077a3088be3b3b92f 265 Pfam PF13344 Haloacid dehalogenase-like hydrolase 6 105 4.0E-20 T 06-07-2017 IPR006357 HAD-superfamily hydrolase, subfamily IIA CAK77_RS03315 3089e79ed7e9871077a3088be3b3b92f 265 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 6 229 4.2E-48 T 06-07-2017 IPR006357 HAD-superfamily hydrolase, subfamily IIA CAK77_RS03315 3089e79ed7e9871077a3088be3b3b92f 265 Gene3D G3DSA:3.40.50.10410 77 177 3.9E-24 T 06-07-2017 IPR023215 Nitrophenylphosphatase-like domain CAK77_RS03315 3089e79ed7e9871077a3088be3b3b92f 265 SUPERFAMILY SSF56784 5 259 5.91E-56 T 06-07-2017 IPR023214 HAD-like domain CAK77_RS03315 3089e79ed7e9871077a3088be3b3b92f 265 Pfam PF13242 HAD-hyrolase-like 180 258 2.2E-18 T 06-07-2017 CAK77_RS03315 3089e79ed7e9871077a3088be3b3b92f 265 Gene3D G3DSA:3.40.50.1000 178 262 4.0E-41 T 06-07-2017 IPR023214 HAD-like domain CAK77_RS03315 3089e79ed7e9871077a3088be3b3b92f 265 Gene3D G3DSA:3.40.50.1000 3 76 4.0E-41 T 06-07-2017 IPR023214 HAD-like domain CAK77_RS06945 0e2df3850e9824a35cf4862082ea5eff 426 Gene3D G3DSA:3.40.710.10 36 238 3.9E-67 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK77_RS06945 0e2df3850e9824a35cf4862082ea5eff 426 Gene3D G3DSA:3.40.710.10 276 405 3.9E-67 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK77_RS06945 0e2df3850e9824a35cf4862082ea5eff 426 SUPERFAMILY SSF56601 296 405 1.82E-60 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK77_RS06945 0e2df3850e9824a35cf4862082ea5eff 426 SUPERFAMILY SSF56601 39 239 1.82E-60 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK77_RS06945 0e2df3850e9824a35cf4862082ea5eff 426 Pfam PF00144 Beta-lactamase 58 405 9.3E-56 T 06-07-2017 IPR001466 Beta-lactamase-related CAK77_RS06680 a5cc8bdf1b52ff36c63669c0bbb807ba 463 Gene3D G3DSA:3.40.50.980 141 283 9.8E-29 T 06-07-2017 CAK77_RS06680 a5cc8bdf1b52ff36c63669c0bbb807ba 463 Pfam PF13193 AMP-binding enzyme C-terminal domain 384 455 7.3E-18 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAK77_RS06680 a5cc8bdf1b52ff36c63669c0bbb807ba 463 SUPERFAMILY SSF56801 27 462 3.92E-104 T 06-07-2017 CAK77_RS06680 a5cc8bdf1b52ff36c63669c0bbb807ba 463 ProSitePatterns PS00455 Putative AMP-binding domain signature. 132 143 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK77_RS06680 a5cc8bdf1b52ff36c63669c0bbb807ba 463 Gene3D G3DSA:3.30.300.30 372 461 2.8E-27 T 06-07-2017 CAK77_RS06680 a5cc8bdf1b52ff36c63669c0bbb807ba 463 Pfam PF00501 AMP-binding enzyme 46 368 5.4E-59 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK77_RS06680 a5cc8bdf1b52ff36c63669c0bbb807ba 463 Gene3D G3DSA:2.30.38.10 291 367 3.2E-23 T 06-07-2017 CAK77_RS06680 a5cc8bdf1b52ff36c63669c0bbb807ba 463 Gene3D G3DSA:3.40.50.980 46 140 4.7E-15 T 06-07-2017 CAK77_RS07915 c6dbfd18fd4b22f0fe01af19b612bb94 175 Pfam PF17174 Domain of unknown function (DUF5130) 34 169 2.4E-62 T 06-07-2017 IPR033437 Protein of unknown function DUF5130 CAK77_RS10025 c454db6e1a947b3a4d2b1200c4ed5beb 384 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 121 198 1.7E-19 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAK77_RS10025 c454db6e1a947b3a4d2b1200c4ed5beb 384 SUPERFAMILY SSF47203 227 381 7.41E-41 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS10025 c454db6e1a947b3a4d2b1200c4ed5beb 384 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 228 376 4.4E-31 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS10025 c454db6e1a947b3a4d2b1200c4ed5beb 384 Gene3D G3DSA:1.10.540.10 2 119 1.0E-26 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS10025 c454db6e1a947b3a4d2b1200c4ed5beb 384 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 117 1.7E-22 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS10025 c454db6e1a947b3a4d2b1200c4ed5beb 384 Gene3D G3DSA:2.40.110.10 121 219 7.1E-30 T 06-07-2017 CAK77_RS10025 c454db6e1a947b3a4d2b1200c4ed5beb 384 Gene3D G3DSA:1.20.140.10 220 382 1.8E-49 T 06-07-2017 CAK77_RS10025 c454db6e1a947b3a4d2b1200c4ed5beb 384 SUPERFAMILY SSF56645 3 241 2.49E-65 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK77_RS14850 b478423dd844535da2ee5cd770f4a4d5 458 SUPERFAMILY SSF51905 10 316 7.93E-38 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS14850 b478423dd844535da2ee5cd770f4a4d5 458 SUPERFAMILY SSF51905 419 449 7.93E-38 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS14850 b478423dd844535da2ee5cd770f4a4d5 458 SUPERFAMILY SSF54373 300 405 6.47E-19 T 06-07-2017 CAK77_RS14850 b478423dd844535da2ee5cd770f4a4d5 458 Gene3D G3DSA:1.10.3110.10 124 207 3.0E-11 T 06-07-2017 CAK77_RS14850 b478423dd844535da2ee5cd770f4a4d5 458 Pfam PF01593 Flavin containing amine oxidoreductase 18 449 4.2E-31 T 06-07-2017 IPR002937 Amine oxidase GO:0016491|GO:0055114 CAK77_RS14850 b478423dd844535da2ee5cd770f4a4d5 458 Gene3D G3DSA:3.50.50.60 217 342 2.8E-27 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS14850 b478423dd844535da2ee5cd770f4a4d5 458 Gene3D G3DSA:3.50.50.60 9 112 2.8E-27 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS14850 b478423dd844535da2ee5cd770f4a4d5 458 TIGRFAM TIGR00562 proto_IX_ox: protoporphyrinogen oxidase 10 449 5.3E-35 T 06-07-2017 IPR004572 Protoporphyrinogen oxidase GO:0004729|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.4|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CAK77_RS05980 298692f7f4764616a246cdc94a69bbba 402 SUPERFAMILY SSF51246 330 401 2.67E-17 T 06-07-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAK77_RS05980 298692f7f4764616a246cdc94a69bbba 402 SUPERFAMILY SSF52440 3 113 1.87E-32 T 06-07-2017 IPR016185 Pre-ATP-grasp domain CAK77_RS05980 298692f7f4764616a246cdc94a69bbba 402 Pfam PF02222 ATP-grasp domain 124 304 6.0E-50 T 06-07-2017 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type CAK77_RS05980 298692f7f4764616a246cdc94a69bbba 402 Gene3D G3DSA:3.40.50.20 4 121 3.8E-39 T 06-07-2017 IPR016185 Pre-ATP-grasp domain CAK77_RS05980 298692f7f4764616a246cdc94a69bbba 402 Gene3D G3DSA:3.30.470.20 204 398 5.5E-70 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAK77_RS05980 298692f7f4764616a246cdc94a69bbba 402 Hamap MF_01643 Phosphoribosylglycinamide formyltransferase 2 [purT]. 8 401 51.045 T 06-07-2017 IPR005862 Phosphoribosylglycinamide formyltransferase 2 GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 CAK77_RS05980 298692f7f4764616a246cdc94a69bbba 402 Gene3D G3DSA:3.30.1490.20 124 203 1.3E-23 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CAK77_RS05980 298692f7f4764616a246cdc94a69bbba 402 TIGRFAM TIGR01142 purT: phosphoribosylglycinamide formyltransferase 2 14 400 9.0E-172 T 06-07-2017 IPR005862 Phosphoribosylglycinamide formyltransferase 2 GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 CAK77_RS05980 298692f7f4764616a246cdc94a69bbba 402 SUPERFAMILY SSF56059 114 325 3.89E-54 T 06-07-2017 CAK77_RS00335 f3a02228088722e37d9a0bc1ce562d69 504 Pfam PF00905 Penicillin binding protein transpeptidase domain 160 496 1.0E-64 T 06-07-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CAK77_RS00335 f3a02228088722e37d9a0bc1ce562d69 504 Gene3D G3DSA:3.40.710.10 144 502 9.8E-89 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK77_RS00335 f3a02228088722e37d9a0bc1ce562d69 504 Gene3D G3DSA:3.90.1310.10 75 143 5.2E-5 T 06-07-2017 CAK77_RS00335 f3a02228088722e37d9a0bc1ce562d69 504 SUPERFAMILY SSF56601 98 502 2.39E-75 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK77_RS09290 a108d838b57e362b7d47365fc217d8ba 457 Pfam PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain 4 263 2.9E-71 T 06-07-2017 IPR004255 O-acyltransferase, WSD1, N-terminal GO:0004144|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CAK77_RS09290 a108d838b57e362b7d47365fc217d8ba 457 TIGRFAM TIGR02946 acyl_WS_DGAT: acyltransferase, WS/DGAT/MGAT 4 455 6.6E-150 T 06-07-2017 IPR014292 Acyltransferase, WS/DGAT/MGAT GO:0016746|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CAK77_RS09290 a108d838b57e362b7d47365fc217d8ba 457 Pfam PF06974 Protein of unknown function (DUF1298) 304 454 1.2E-32 T 06-07-2017 IPR009721 O-acyltransferase WSD1, C-terminal GO:0004144 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CAK77_RS09290 a108d838b57e362b7d47365fc217d8ba 457 SUPERFAMILY SSF52777 4 162 4.67E-11 T 06-07-2017 CAK77_RS22525 2be815f2ba0ed67c2c862f4bbba40b0e 179 Gene3D G3DSA:2.40.128.110 9 171 5.6E-59 T 06-07-2017 IPR007372 Lipid/polyisoprenoid-binding, YceI-like CAK77_RS22525 2be815f2ba0ed67c2c862f4bbba40b0e 179 SUPERFAMILY SSF101874 9 171 4.71E-56 T 06-07-2017 IPR007372 Lipid/polyisoprenoid-binding, YceI-like CAK77_RS22525 2be815f2ba0ed67c2c862f4bbba40b0e 179 Pfam PF04264 YceI-like domain 13 171 1.2E-47 T 06-07-2017 IPR007372 Lipid/polyisoprenoid-binding, YceI-like CAK77_RS22525 2be815f2ba0ed67c2c862f4bbba40b0e 179 SMART SM00867 12 172 1.6E-65 T 06-07-2017 IPR007372 Lipid/polyisoprenoid-binding, YceI-like CAK77_RS15175 b050629df0a23d8584effb2525f68e68 507 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 14 458 1.4E-150 T 06-07-2017 IPR005839 Methylthiotransferase GO:0016740|GO:0043412|GO:0051539 CAK77_RS15175 b050629df0a23d8584effb2525f68e68 507 SMART SM00729 156 380 4.9E-61 T 06-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CAK77_RS15175 b050629df0a23d8584effb2525f68e68 507 Gene3D G3DSA:3.80.30.20 156 393 2.0E-82 T 06-07-2017 IPR023404 Radical SAM, alpha/beta horseshoe CAK77_RS15175 b050629df0a23d8584effb2525f68e68 507 Pfam PF04055 Radical SAM superfamily 160 337 8.0E-30 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 CAK77_RS15175 b050629df0a23d8584effb2525f68e68 507 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 15 456 1.3E-141 T 06-07-2017 CAK77_RS15175 b050629df0a23d8584effb2525f68e68 507 SUPERFAMILY SSF102114 142 384 1.57E-59 T 06-07-2017 CAK77_RS15175 b050629df0a23d8584effb2525f68e68 507 Pfam PF00919 Uncharacterized protein family UPF0004 15 113 1.4E-27 T 06-07-2017 IPR013848 Methylthiotransferase, N-terminal GO:0003824|GO:0009451|GO:0051539 CAK77_RS15175 b050629df0a23d8584effb2525f68e68 507 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 13 462 66.965 T 06-07-2017 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 CAK77_RS15175 b050629df0a23d8584effb2525f68e68 507 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 160 180 - T 06-07-2017 IPR020612 Methylthiotransferase, conserved site GO:0051539 CAK77_RS12470 f8ec8bb88ca6e7de65d5f68aefd25707 333 SUPERFAMILY SSF50129 14 174 1.32E-46 T 06-07-2017 IPR011032 GroES-like CAK77_RS12470 f8ec8bb88ca6e7de65d5f68aefd25707 333 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 30 137 2.2E-31 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAK77_RS12470 f8ec8bb88ca6e7de65d5f68aefd25707 333 TIGRFAM TIGR02822 adh_fam_2: zinc-binding alcohol dehydrogenase family protein 3 332 6.3E-173 T 06-07-2017 IPR014187 Alcohol dehydrogenase, zinc-binding type 2 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396 CAK77_RS12470 f8ec8bb88ca6e7de65d5f68aefd25707 333 SUPERFAMILY SSF51735 143 301 1.14E-28 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS12470 f8ec8bb88ca6e7de65d5f68aefd25707 333 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 63 77 - T 06-07-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CAK77_RS12470 f8ec8bb88ca6e7de65d5f68aefd25707 333 Gene3D G3DSA:3.90.180.10 3 173 6.2E-57 T 06-07-2017 IPR011032 GroES-like CAK77_RS12470 f8ec8bb88ca6e7de65d5f68aefd25707 333 Gene3D G3DSA:3.40.50.720 174 279 9.3E-10 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS15595 59242d5281adb3e8e3b22ea994456330 189 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 18 169 17.521 T 06-07-2017 IPR003728 Ribosome maturation factor RimP GO:0042274 CAK77_RS15595 59242d5281adb3e8e3b22ea994456330 189 Pfam PF02576 Putative ribosome maturation factor RimP 26 164 1.7E-19 T 06-07-2017 IPR003728 Ribosome maturation factor RimP GO:0042274 CAK77_RS15595 59242d5281adb3e8e3b22ea994456330 189 SUPERFAMILY SSF75420 17 98 1.24E-12 T 06-07-2017 IPR028989 Ribosome maturation factor RimP, N-terminal CAK77_RS15595 59242d5281adb3e8e3b22ea994456330 189 Gene3D G3DSA:3.30.300.70 17 95 4.7E-11 T 06-07-2017 IPR028989 Ribosome maturation factor RimP, N-terminal CAK77_RS23235 c2d222600bcbbeb0d6d9b61c5ae340b1 302 SUPERFAMILY SSF51556 23 294 4.48E-50 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK77_RS23235 c2d222600bcbbeb0d6d9b61c5ae340b1 302 Pfam PF04909 Amidohydrolase 24 294 9.0E-32 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAK77_RS23235 c2d222600bcbbeb0d6d9b61c5ae340b1 302 Gene3D G3DSA:3.20.20.140 22 296 2.3E-60 T 06-07-2017 CAK77_RS10595 d174783f747b46bbdec75cc5a19ea58d 285 SUPERFAMILY SSF161098 87 270 1.22E-34 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS10595 d174783f747b46bbdec75cc5a19ea58d 285 Gene3D G3DSA:1.10.3720.10 87 278 3.7E-28 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS10595 d174783f747b46bbdec75cc5a19ea58d 285 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 109 277 2.5E-29 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS05065 c31d48133dc8331f41090c4ac02be0e9 348 Pfam PF02470 MlaD protein 48 122 1.4E-15 T 06-07-2017 IPR003399 Mce/MlaD CAK77_RS05065 c31d48133dc8331f41090c4ac02be0e9 348 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 24 298 1.8E-49 T 06-07-2017 IPR005693 Virulence factor Mce protein CAK77_RS07940 318ed679308ad4bba82913c4f4e3ae8a 159 Gene3D G3DSA:3.40.1400.10 1 149 3.0E-51 T 06-07-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CAK77_RS07940 318ed679308ad4bba82913c4f4e3ae8a 159 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 3 147 2.4E-54 T 06-07-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CAK77_RS07940 318ed679308ad4bba82913c4f4e3ae8a 159 TIGRFAM TIGR02133 RPI_actino: ribose 5-phosphate isomerase 1 148 1.5E-64 T 06-07-2017 IPR011860 Ribose 5-phosphate isomerase GO:0004751 CAK77_RS07940 318ed679308ad4bba82913c4f4e3ae8a 159 PIRSF PIRSF005384 1 149 1.0E-47 T 06-07-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CAK77_RS07940 318ed679308ad4bba82913c4f4e3ae8a 159 Pfam PF02502 Ribose/Galactose Isomerase 3 140 1.2E-41 T 06-07-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CAK77_RS07940 318ed679308ad4bba82913c4f4e3ae8a 159 SUPERFAMILY SSF89623 1 152 6.67E-51 T 06-07-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CAK77_RS22760 ce2cee5ee08a76167bb90a377683c8ab 305 SUPERFAMILY SSF53474 8 298 1.84E-54 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS22760 ce2cee5ee08a76167bb90a377683c8ab 305 PRINTS PR00412 Epoxide hydrolase signature 53 68 6.1E-16 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK77_RS22760 ce2cee5ee08a76167bb90a377683c8ab 305 PRINTS PR00412 Epoxide hydrolase signature 274 296 6.1E-16 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK77_RS22760 ce2cee5ee08a76167bb90a377683c8ab 305 PRINTS PR00412 Epoxide hydrolase signature 99 112 6.1E-16 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK77_RS22760 ce2cee5ee08a76167bb90a377683c8ab 305 PRINTS PR00412 Epoxide hydrolase signature 33 51 6.1E-16 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK77_RS22760 ce2cee5ee08a76167bb90a377683c8ab 305 Gene3D G3DSA:3.40.50.1820 9 297 1.7E-54 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS22760 ce2cee5ee08a76167bb90a377683c8ab 305 Pfam PF00561 alpha/beta hydrolase fold 27 284 1.7E-18 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS00755 249ce912a1ce3bd2939af3726b0995b4 207 PIRSF PIRSF000349 1 202 4.5E-76 T 06-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAK77_RS00755 249ce912a1ce3bd2939af3726b0995b4 207 PRINTS PR01703 Manganese superoxide dismutase signature 67 80 1.3E-21 T 06-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAK77_RS00755 249ce912a1ce3bd2939af3726b0995b4 207 PRINTS PR01703 Manganese superoxide dismutase signature 120 128 1.3E-21 T 06-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAK77_RS00755 249ce912a1ce3bd2939af3726b0995b4 207 PRINTS PR01703 Manganese superoxide dismutase signature 158 170 1.3E-21 T 06-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAK77_RS00755 249ce912a1ce3bd2939af3726b0995b4 207 PRINTS PR01703 Manganese superoxide dismutase signature 7 18 1.3E-21 T 06-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAK77_RS00755 249ce912a1ce3bd2939af3726b0995b4 207 PRINTS PR01703 Manganese superoxide dismutase signature 28 41 1.3E-21 T 06-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAK77_RS00755 249ce912a1ce3bd2939af3726b0995b4 207 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 91 193 9.4E-36 T 06-07-2017 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAK77_RS00755 249ce912a1ce3bd2939af3726b0995b4 207 SUPERFAMILY SSF46609 3 88 1.44E-30 T 06-07-2017 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAK77_RS00755 249ce912a1ce3bd2939af3726b0995b4 207 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 160 167 - T 06-07-2017 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAK77_RS00755 249ce912a1ce3bd2939af3726b0995b4 207 SUPERFAMILY SSF54719 84 198 2.36E-44 T 06-07-2017 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAK77_RS00755 249ce912a1ce3bd2939af3726b0995b4 207 Gene3D G3DSA:1.10.287.990 21 84 7.6E-22 T 06-07-2017 CAK77_RS00755 249ce912a1ce3bd2939af3726b0995b4 207 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 3 84 1.7E-31 T 06-07-2017 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAK77_RS21745 8a2c4b6dca933f3cc08ab02aa5556da9 474 SUPERFAMILY SSF54373 308 414 1.77E-30 T 06-07-2017 CAK77_RS21745 8a2c4b6dca933f3cc08ab02aa5556da9 474 Gene3D G3DSA:3.50.50.60 223 237 3.4E-14 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS21745 8a2c4b6dca933f3cc08ab02aa5556da9 474 Gene3D G3DSA:3.50.50.60 117 131 3.4E-14 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS21745 8a2c4b6dca933f3cc08ab02aa5556da9 474 Gene3D G3DSA:3.50.50.60 19 69 3.4E-14 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS21745 8a2c4b6dca933f3cc08ab02aa5556da9 474 Pfam PF01593 Flavin containing amine oxidoreductase 27 464 3.0E-63 T 06-07-2017 IPR002937 Amine oxidase GO:0016491|GO:0055114 CAK77_RS21745 8a2c4b6dca933f3cc08ab02aa5556da9 474 Gene3D G3DSA:1.10.405.10 132 210 4.2E-22 T 06-07-2017 CAK77_RS21745 8a2c4b6dca933f3cc08ab02aa5556da9 474 SUPERFAMILY SSF51905 18 326 4.01E-54 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS21745 8a2c4b6dca933f3cc08ab02aa5556da9 474 SUPERFAMILY SSF51905 424 467 4.01E-54 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS21745 8a2c4b6dca933f3cc08ab02aa5556da9 474 PRINTS PR00757 Flavin-containing amine oxidase signature 394 413 2.3E-13 T 06-07-2017 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 CAK77_RS21745 8a2c4b6dca933f3cc08ab02aa5556da9 474 PRINTS PR00757 Flavin-containing amine oxidase signature 311 330 2.3E-13 T 06-07-2017 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 CAK77_RS21745 8a2c4b6dca933f3cc08ab02aa5556da9 474 PRINTS PR00757 Flavin-containing amine oxidase signature 415 437 2.3E-13 T 06-07-2017 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 CAK77_RS21745 8a2c4b6dca933f3cc08ab02aa5556da9 474 PRINTS PR00757 Flavin-containing amine oxidase signature 19 38 2.3E-13 T 06-07-2017 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 CAK77_RS21745 8a2c4b6dca933f3cc08ab02aa5556da9 474 Gene3D G3DSA:3.90.660.10 239 414 2.9E-52 T 06-07-2017 CAK77_RS15675 ef490cfbcbb22076503b7b2164857543 207 Gene3D G3DSA:1.10.10.60 19 62 6.9E-19 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS15675 ef490cfbcbb22076503b7b2164857543 207 SUPERFAMILY SSF48498 88 199 1.93E-13 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS15675 ef490cfbcbb22076503b7b2164857543 207 Pfam PF16859 Bacterial transcriptional repressor C-terminal 84 195 1.9E-22 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS15675 ef490cfbcbb22076503b7b2164857543 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 67 3.5E-16 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS15675 ef490cfbcbb22076503b7b2164857543 207 SUPERFAMILY SSF46689 23 75 6.98E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS15675 ef490cfbcbb22076503b7b2164857543 207 Gene3D G3DSA:1.10.357.10 63 199 6.2E-22 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS15675 ef490cfbcbb22076503b7b2164857543 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 68 4.7E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS15675 ef490cfbcbb22076503b7b2164857543 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 24 37 4.7E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS15675 ef490cfbcbb22076503b7b2164857543 207 ProSitePatterns PS01081 TetR-type HTH domain signature. 36 66 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CAK77_RS15250 0221391f5412f70bc9096412c2d5075c 147 SUPERFAMILY SSF54427 13 137 2.12E-29 T 06-07-2017 IPR032710 NTF2-like domain CAK77_RS15250 0221391f5412f70bc9096412c2d5075c 147 Gene3D G3DSA:3.10.450.50 4 133 7.2E-37 T 06-07-2017 IPR032710 NTF2-like domain CAK77_RS15250 0221391f5412f70bc9096412c2d5075c 147 Pfam PF07858 Limonene-1,2-epoxide hydrolase catalytic domain 12 133 1.0E-37 T 06-07-2017 IPR013100 Limonene-1,2-epoxide hydrolase CAK77_RS13845 b1eae3ea6d2fce32fd423800092b676d 317 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 1 307 39.353 T 06-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CAK77_RS13845 b1eae3ea6d2fce32fd423800092b676d 317 Gene3D G3DSA:3.40.50.1370 1 146 9.4E-49 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CAK77_RS13845 b1eae3ea6d2fce32fd423800092b676d 317 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 49 56 - T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CAK77_RS13845 b1eae3ea6d2fce32fd423800092b676d 317 PRINTS PR00101 Aspartate carbamoyltransferase signature 137 154 3.3E-32 T 06-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CAK77_RS13845 b1eae3ea6d2fce32fd423800092b676d 317 PRINTS PR00101 Aspartate carbamoyltransferase signature 262 267 3.3E-32 T 06-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CAK77_RS13845 b1eae3ea6d2fce32fd423800092b676d 317 PRINTS PR00101 Aspartate carbamoyltransferase signature 39 61 3.3E-32 T 06-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CAK77_RS13845 b1eae3ea6d2fce32fd423800092b676d 317 PRINTS PR00101 Aspartate carbamoyltransferase signature 221 230 3.3E-32 T 06-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CAK77_RS13845 b1eae3ea6d2fce32fd423800092b676d 317 PRINTS PR00101 Aspartate carbamoyltransferase signature 77 86 3.3E-32 T 06-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CAK77_RS13845 b1eae3ea6d2fce32fd423800092b676d 317 PRINTS PR00101 Aspartate carbamoyltransferase signature 286 300 3.3E-32 T 06-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CAK77_RS13845 b1eae3ea6d2fce32fd423800092b676d 317 SUPERFAMILY SSF53671 1 305 4.32E-91 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CAK77_RS13845 b1eae3ea6d2fce32fd423800092b676d 317 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 158 303 6.0E-20 T 06-07-2017 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 CAK77_RS13845 b1eae3ea6d2fce32fd423800092b676d 317 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 2 150 2.7E-37 T 06-07-2017 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 CAK77_RS13845 b1eae3ea6d2fce32fd423800092b676d 317 Gene3D G3DSA:3.40.50.1370 147 284 6.2E-46 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CAK77_RS13845 b1eae3ea6d2fce32fd423800092b676d 317 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 258 267 2.3E-18 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CAK77_RS13845 b1eae3ea6d2fce32fd423800092b676d 317 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 270 293 2.3E-18 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CAK77_RS13845 b1eae3ea6d2fce32fd423800092b676d 317 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 138 149 2.3E-18 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CAK77_RS13845 b1eae3ea6d2fce32fd423800092b676d 317 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 49 68 2.3E-18 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CAK77_RS13845 b1eae3ea6d2fce32fd423800092b676d 317 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 2 304 6.3E-84 T 06-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CAK77_RS11885 399083f845e55209e0fee69ee49ea027 198 Gene3D G3DSA:1.10.357.10 2 192 6.8E-30 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS11885 399083f845e55209e0fee69ee49ea027 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 56 2.7E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS11885 399083f845e55209e0fee69ee49ea027 198 SUPERFAMILY SSF48498 78 182 1.56E-19 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS11885 399083f845e55209e0fee69ee49ea027 198 SUPERFAMILY SSF46689 4 73 7.48E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS23015 897ab0ef2959882dd66205a835aca649 139 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 17 132 3.8E-16 T 06-07-2017 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-75105 CAK77_RS23015 897ab0ef2959882dd66205a835aca649 139 SUPERFAMILY SSF54637 5 136 7.63E-27 T 06-07-2017 IPR029069 HotDog domain CAK77_RS23015 897ab0ef2959882dd66205a835aca649 139 Gene3D G3DSA:3.10.129.10 5 135 1.6E-31 T 06-07-2017 IPR029069 HotDog domain CAK77_RS23015 897ab0ef2959882dd66205a835aca649 139 Pfam PF03061 Thioesterase superfamily 47 119 6.7E-13 T 06-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 CAK77_RS03785 a386a9c19b3aefb10aad9c3fce173fb5 374 Gene3D G3DSA:3.20.20.70 5 372 9.9E-132 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK77_RS03785 a386a9c19b3aefb10aad9c3fce173fb5 374 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 6 351 1.3E-86 T 06-07-2017 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 CAK77_RS03785 a386a9c19b3aefb10aad9c3fce173fb5 374 SUPERFAMILY SSF51395 2 372 2.44E-123 T 06-07-2017 CAK77_RS05575 a73beaa7dd8ccc76c4ce30d16b0c0a04 272 SUPERFAMILY SSF55729 87 260 1.28E-16 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS05575 a73beaa7dd8ccc76c4ce30d16b0c0a04 272 Pfam PF00583 Acetyltransferase (GNAT) family 185 256 2.1E-5 T 06-07-2017 IPR000182 GNAT domain GO:0008080 CAK77_RS05575 a73beaa7dd8ccc76c4ce30d16b0c0a04 272 Gene3D G3DSA:3.40.630.30 117 258 1.3E-11 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS10510 3781fd09b1cf64c51008644fce380565 278 SUPERFAMILY SSF53335 7 260 5.63E-72 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS10510 3781fd09b1cf64c51008644fce380565 278 Gene3D G3DSA:3.40.50.150 71 268 7.0E-68 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS10510 3781fd09b1cf64c51008644fce380565 278 Pfam PF08704 tRNA methyltransferase complex GCD14 subunit 73 237 2.8E-21 T 06-07-2017 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829 CAK77_RS10510 3781fd09b1cf64c51008644fce380565 278 Pfam PF14801 tRNA methyltransferase complex GCD14 subunit N-term 4 54 1.3E-27 T 06-07-2017 CAK77_RS10510 3781fd09b1cf64c51008644fce380565 278 PIRSF PIRSF017269 1 270 5.0E-88 T 06-07-2017 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829 CAK77_RS10510 3781fd09b1cf64c51008644fce380565 278 Gene3D G3DSA:3.10.330.20 2 67 6.7E-31 T 06-07-2017 CAK77_RS06885 68bbeddb481ae28d4381409878caba35 391 SUPERFAMILY SSF50331 237 384 1.02E-20 T 06-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal CAK77_RS06885 68bbeddb481ae28d4381409878caba35 391 SUPERFAMILY SSF52540 4 243 7.51E-86 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS06885 68bbeddb481ae28d4381409878caba35 391 Gene3D G3DSA:2.40.50.140 285 369 2.7E-9 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS06885 68bbeddb481ae28d4381409878caba35 391 Gene3D G3DSA:3.40.50.300 4 235 1.9E-77 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS06885 68bbeddb481ae28d4381409878caba35 391 Pfam PF00005 ABC transporter 21 162 5.2E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK77_RS06885 68bbeddb481ae28d4381409878caba35 391 SMART SM00382 29 220 6.2E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS06885 68bbeddb481ae28d4381409878caba35 391 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK77_RS06885 68bbeddb481ae28d4381409878caba35 391 Gene3D G3DSA:2.40.50.100 370 384 5.5E-7 T 06-07-2017 CAK77_RS06885 68bbeddb481ae28d4381409878caba35 391 Gene3D G3DSA:2.40.50.100 240 284 5.5E-7 T 06-07-2017 CAK77_RS16755 e1d2c1ffc0c4cc01aac4a9a14d4b7c3c 243 Pfam PF03591 AzlC protein 26 160 3.0E-32 T 06-07-2017 IPR011606 Branched-chain amino acid transport, permease CAK77_RS23150 75ce2f40ceb1abb15c5d2396657c360f 399 Gene3D G3DSA:3.30.1540.10 223 305 1.5E-30 T 06-07-2017 CAK77_RS23150 75ce2f40ceb1abb15c5d2396657c360f 399 Gene3D G3DSA:3.40.50.10540 306 399 1.6E-107 T 06-07-2017 IPR023606 CoA-transferase family III domain CAK77_RS23150 75ce2f40ceb1abb15c5d2396657c360f 399 Gene3D G3DSA:3.40.50.10540 2 216 1.6E-107 T 06-07-2017 IPR023606 CoA-transferase family III domain CAK77_RS23150 75ce2f40ceb1abb15c5d2396657c360f 399 SUPERFAMILY SSF89796 3 399 3.01E-130 T 06-07-2017 IPR023606 CoA-transferase family III domain CAK77_RS23150 75ce2f40ceb1abb15c5d2396657c360f 399 Pfam PF02515 CoA-transferase family III 5 375 4.1E-124 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 CAK77_RS21815 6b3adc7db550a88f0001cd9f042cdcf4 283 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK77_RS21815 6b3adc7db550a88f0001cd9f042cdcf4 283 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 2.1E-31 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS21815 6b3adc7db550a88f0001cd9f042cdcf4 283 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 2.1E-31 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS21815 6b3adc7db550a88f0001cd9f042cdcf4 283 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 2.1E-31 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS21815 6b3adc7db550a88f0001cd9f042cdcf4 283 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 200 220 2.1E-31 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS21815 6b3adc7db550a88f0001cd9f042cdcf4 283 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 2.1E-31 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS21815 6b3adc7db550a88f0001cd9f042cdcf4 283 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 2.1E-31 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS21815 6b3adc7db550a88f0001cd9f042cdcf4 283 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 5.9E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS21815 6b3adc7db550a88f0001cd9f042cdcf4 283 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 5.9E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS21815 6b3adc7db550a88f0001cd9f042cdcf4 283 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 5.9E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS21815 6b3adc7db550a88f0001cd9f042cdcf4 283 Pfam PF00106 short chain dehydrogenase 10 193 2.6E-56 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS21815 6b3adc7db550a88f0001cd9f042cdcf4 283 Gene3D G3DSA:3.40.50.720 5 219 2.3E-72 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS21815 6b3adc7db550a88f0001cd9f042cdcf4 283 SUPERFAMILY SSF51735 6 253 5.06E-74 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS21815 6b3adc7db550a88f0001cd9f042cdcf4 283 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 10 187 0.0044 T 06-07-2017 CAK77_RS20835 62183ce7b11c4e1f9c8abb960267ad41 63 SUPERFAMILY SSF54862 2 61 2.01E-8 T 06-07-2017 CAK77_RS20835 62183ce7b11c4e1f9c8abb960267ad41 63 Gene3D G3DSA:3.30.70.20 1 62 2.1E-15 T 06-07-2017 CAK77_RS20835 62183ce7b11c4e1f9c8abb960267ad41 63 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 8 58 1.4E-11 T 06-07-2017 CAK77_RS08540 cdd853148d6290b456e8bd4ee7b693ff 302 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 246 263 - T 06-07-2017 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 CAK77_RS08540 cdd853148d6290b456e8bd4ee7b693ff 302 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 73 301 36.597 T 06-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CAK77_RS08540 cdd853148d6290b456e8bd4ee7b693ff 302 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 73 300 9.6E-72 T 06-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CAK77_RS08540 cdd853148d6290b456e8bd4ee7b693ff 302 SUPERFAMILY SSF64005 70 295 2.49E-80 T 06-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CAK77_RS08540 cdd853148d6290b456e8bd4ee7b693ff 302 Gene3D G3DSA:3.40.1180.10 67 300 2.5E-87 T 06-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CAK77_RS08540 cdd853148d6290b456e8bd4ee7b693ff 302 Pfam PF01255 Putative undecaprenyl diphosphate synthase 80 300 9.2E-71 T 06-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CAK77_RS15115 17036b0eb9776a4bb67b6c44d321b3cf 154 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 150 77.978 T 06-07-2017 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 CAK77_RS15115 17036b0eb9776a4bb67b6c44d321b3cf 154 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 144 1.7E-46 T 06-07-2017 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 CAK77_RS15115 17036b0eb9776a4bb67b6c44d321b3cf 154 Pfam PF03477 ATP cone domain 47 131 1.2E-13 T 06-07-2017 IPR005144 ATP-cone domain Reactome: R-HSA-499943 CAK77_RS02700 f86ba4c4bc611ec1edeeb4c12768da6f 226 Pfam PF05423 Mycobacterium membrane protein 139 208 4.8E-8 T 06-07-2017 IPR008693 Transport accessory protein MmpS CAK77_RS11865 eb82fd989ccd6eaa013a0874a47997c4 421 PIRSF PIRSF006728 1 421 6.5E-110 T 06-07-2017 IPR008135 Competence-induced protein CinA CAK77_RS11865 eb82fd989ccd6eaa013a0874a47997c4 421 Gene3D G3DSA:3.90.950.20 268 419 2.3E-53 T 06-07-2017 IPR008136 CinA, C-terminal CAK77_RS11865 eb82fd989ccd6eaa013a0874a47997c4 421 SUPERFAMILY SSF53218 138 175 6.94E-33 T 06-07-2017 IPR001453 MoaB/Mog domain CAK77_RS11865 eb82fd989ccd6eaa013a0874a47997c4 421 SUPERFAMILY SSF53218 2 106 6.94E-33 T 06-07-2017 IPR001453 MoaB/Mog domain CAK77_RS11865 eb82fd989ccd6eaa013a0874a47997c4 421 SUPERFAMILY SSF142433 268 419 5.23E-51 T 06-07-2017 IPR008136 CinA, C-terminal CAK77_RS11865 eb82fd989ccd6eaa013a0874a47997c4 421 Pfam PF02464 Competence-damaged protein 270 419 8.8E-53 T 06-07-2017 IPR008136 CinA, C-terminal CAK77_RS11865 eb82fd989ccd6eaa013a0874a47997c4 421 Pfam PF00994 Probable molybdopterin binding domain 5 173 1.4E-31 T 06-07-2017 IPR001453 MoaB/Mog domain CAK77_RS11865 eb82fd989ccd6eaa013a0874a47997c4 421 Hamap MF_00226_B Putative competence-damage inducible protein [cinA]. 1 421 124.759 T 06-07-2017 IPR008135 Competence-induced protein CinA CAK77_RS11865 eb82fd989ccd6eaa013a0874a47997c4 421 SMART SM00852 5 179 3.8E-29 T 06-07-2017 IPR001453 MoaB/Mog domain CAK77_RS11865 eb82fd989ccd6eaa013a0874a47997c4 421 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 279 418 1.5E-42 T 06-07-2017 IPR008136 CinA, C-terminal CAK77_RS11865 eb82fd989ccd6eaa013a0874a47997c4 421 Gene3D G3DSA:3.40.980.10 2 100 2.3E-31 T 06-07-2017 IPR001453 MoaB/Mog domain CAK77_RS11865 eb82fd989ccd6eaa013a0874a47997c4 421 Gene3D G3DSA:3.40.980.10 136 214 2.3E-31 T 06-07-2017 IPR001453 MoaB/Mog domain CAK77_RS12990 2c94bb34184841157688150df4ecbf93 104 Pfam PF00893 Small Multidrug Resistance protein 1 93 2.3E-29 T 06-07-2017 IPR000390 Small multidrug resistance protein family GO:0016021 CAK77_RS12990 2c94bb34184841157688150df4ecbf93 104 SUPERFAMILY SSF103481 5 103 5.75E-19 T 06-07-2017 CAK77_RS22185 5336063048c575edd6ff062fd1c15d4e 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 4.1E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS22185 5336063048c575edd6ff062fd1c15d4e 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 4.1E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS22185 5336063048c575edd6ff062fd1c15d4e 205 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 63 5.3E-16 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS22185 5336063048c575edd6ff062fd1c15d4e 205 SUPERFAMILY SSF46689 5 88 1.44E-20 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS22185 5336063048c575edd6ff062fd1c15d4e 205 Gene3D G3DSA:1.10.357.10 4 198 1.2E-43 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS22185 5336063048c575edd6ff062fd1c15d4e 205 SUPERFAMILY SSF48498 84 195 1.08E-7 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS24125 fb5e2a833523f9085c508711f8e473ba 288 Pfam PF08044 Domain of unknown function (DUF1707) 9 61 2.0E-18 T 06-07-2017 IPR012551 Protein of unknown function DUF1707 CAK77_RS08905 a5df8810528343f6d495ac79fdcadedf 216 Gene3D G3DSA:3.40.50.850 7 210 2.6E-49 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAK77_RS08905 a5df8810528343f6d495ac79fdcadedf 216 Pfam PF00857 Isochorismatase family 12 195 7.2E-29 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAK77_RS08905 a5df8810528343f6d495ac79fdcadedf 216 SUPERFAMILY SSF52499 7 208 2.09E-41 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAK77_RS01675 b1c12d52cb0b7f3e2131f4a85f2cdff1 82 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 32 81 1.0E-19 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS01675 b1c12d52cb0b7f3e2131f4a85f2cdff1 82 TIGRFAM TIGR00165 S18: ribosomal protein bS18 23 81 1.0E-23 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS01675 b1c12d52cb0b7f3e2131f4a85f2cdff1 82 PRINTS PR00974 Ribosomal protein S18 family signature 49 56 1.4E-17 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS01675 b1c12d52cb0b7f3e2131f4a85f2cdff1 82 PRINTS PR00974 Ribosomal protein S18 family signature 71 81 1.4E-17 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS01675 b1c12d52cb0b7f3e2131f4a85f2cdff1 82 PRINTS PR00974 Ribosomal protein S18 family signature 57 71 1.4E-17 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS01675 b1c12d52cb0b7f3e2131f4a85f2cdff1 82 PRINTS PR00974 Ribosomal protein S18 family signature 39 49 1.4E-17 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS01675 b1c12d52cb0b7f3e2131f4a85f2cdff1 82 Gene3D G3DSA:4.10.640.10 20 81 1.7E-27 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS01675 b1c12d52cb0b7f3e2131f4a85f2cdff1 82 ProSitePatterns PS00057 Ribosomal protein S18 signature. 32 55 - T 06-07-2017 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS01675 b1c12d52cb0b7f3e2131f4a85f2cdff1 82 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 4 82 16.764 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS01675 b1c12d52cb0b7f3e2131f4a85f2cdff1 82 Pfam PF01084 Ribosomal protein S18 31 79 3.0E-23 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS01675 b1c12d52cb0b7f3e2131f4a85f2cdff1 82 SUPERFAMILY SSF46911 16 81 5.75E-24 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS05625 9875792527b8b000cb93c4212f56e40f 140 Pfam PF05423 Mycobacterium membrane protein 1 140 9.0E-56 T 06-07-2017 IPR008693 Transport accessory protein MmpS CAK77_RS12050 0d0d7e8e9d2b24f65d7f793caa6581f7 218 Gene3D G3DSA:1.20.120.450 4 52 8.9E-6 T 06-07-2017 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase CAK77_RS12050 0d0d7e8e9d2b24f65d7f793caa6581f7 218 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 6 149 9.2E-19 T 06-07-2017 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 CAK77_RS12050 0d0d7e8e9d2b24f65d7f793caa6581f7 218 SUPERFAMILY SSF109854 3 151 9.16E-9 T 06-07-2017 CAK77_RS18515 78baeb9b45848de0769ab14416e793dd 585 Pfam PF00732 GMC oxidoreductase 17 289 7.4E-12 T 06-07-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CAK77_RS18515 78baeb9b45848de0769ab14416e793dd 585 Pfam PF05199 GMC oxidoreductase 475 532 8.4E-11 T 06-07-2017 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 CAK77_RS18515 78baeb9b45848de0769ab14416e793dd 585 Gene3D G3DSA:3.50.50.60 471 539 8.1E-80 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS18515 78baeb9b45848de0769ab14416e793dd 585 Gene3D G3DSA:3.50.50.60 14 137 8.1E-80 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS18515 78baeb9b45848de0769ab14416e793dd 585 Gene3D G3DSA:3.50.50.60 209 314 8.1E-80 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS18515 78baeb9b45848de0769ab14416e793dd 585 Gene3D G3DSA:3.50.50.60 410 423 8.1E-80 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS18515 78baeb9b45848de0769ab14416e793dd 585 SUPERFAMILY SSF51905 12 316 8.48E-47 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS18515 78baeb9b45848de0769ab14416e793dd 585 SUPERFAMILY SSF51905 477 538 8.48E-47 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS02995 9b8ca15ef9b1f1a31b4608e7acef48cb 292 Gene3D G3DSA:3.40.50.1980 21 169 3.6E-34 T 06-07-2017 CAK77_RS02995 9b8ca15ef9b1f1a31b4608e7acef48cb 292 Gene3D G3DSA:3.40.50.1980 210 291 6.0E-9 T 06-07-2017 CAK77_RS02995 9b8ca15ef9b1f1a31b4608e7acef48cb 292 SUPERFAMILY SSF53807 30 292 4.12E-57 T 06-07-2017 CAK77_RS02995 9b8ca15ef9b1f1a31b4608e7acef48cb 292 Pfam PF01297 Zinc-uptake complex component A periplasmic 35 289 2.1E-44 T 06-07-2017 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 CAK77_RS00780 37287ce42a04478fe7cb5db1c2ed399a 287 SUPERFAMILY SSF51695 27 278 3.14E-66 T 06-07-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CAK77_RS00780 37287ce42a04478fe7cb5db1c2ed399a 287 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 33 272 1.1E-48 T 06-07-2017 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 CAK77_RS00780 37287ce42a04478fe7cb5db1c2ed399a 287 Gene3D G3DSA:3.20.20.190 25 280 8.7E-72 T 06-07-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CAK77_RS07745 e34e6de1e4ae6de0960bb9275049008d 267 PIRSF PIRSF000126 4 266 3.9E-68 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS07745 e34e6de1e4ae6de0960bb9275049008d 267 Pfam PF00106 short chain dehydrogenase 12 192 2.9E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS07745 e34e6de1e4ae6de0960bb9275049008d 267 Gene3D G3DSA:3.40.50.720 11 247 1.0E-49 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS07745 e34e6de1e4ae6de0960bb9275049008d 267 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 10 193 0.006 T 06-07-2017 CAK77_RS07745 e34e6de1e4ae6de0960bb9275049008d 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 1.1E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS07745 e34e6de1e4ae6de0960bb9275049008d 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 1.1E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS07745 e34e6de1e4ae6de0960bb9275049008d 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 1.1E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS07745 e34e6de1e4ae6de0960bb9275049008d 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 1.1E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS07745 e34e6de1e4ae6de0960bb9275049008d 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 1.1E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS07745 e34e6de1e4ae6de0960bb9275049008d 267 SUPERFAMILY SSF51735 9 255 1.36E-52 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS07745 e34e6de1e4ae6de0960bb9275049008d 267 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK77_RS06925 da013dcde2bbbb78fe80383ba14f3e9e 207 Pfam PF01914 MarC family integral membrane protein 7 202 6.7E-44 T 06-07-2017 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 CAK77_RS06925 da013dcde2bbbb78fe80383ba14f3e9e 207 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 6 198 1.3E-39 T 06-07-2017 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 CAK77_RS20075 8ac1e5b42bd706e387982d7684187bfe 313 SUPERFAMILY SSF47240 18 286 1.45E-50 T 06-07-2017 IPR009078 Ferritin-like superfamily CAK77_RS20075 8ac1e5b42bd706e387982d7684187bfe 313 Pfam PF00268 Ribonucleotide reductase, small chain 28 275 3.8E-17 T 06-07-2017 IPR000358 Ribonucleotide reductase small subunit GO:0009186|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CAK77_RS20075 8ac1e5b42bd706e387982d7684187bfe 313 Gene3D G3DSA:1.10.620.20 22 275 1.7E-44 T 06-07-2017 IPR012348 Ribonucleotide reductase-related GO:0016491|GO:0055114 Reactome: R-HSA-499943 CAK77_RS04245 db2ef3454b1af49bee7b6a0d83c03ff1 384 SUPERFAMILY SSF53901 228 369 6.91E-15 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS04245 db2ef3454b1af49bee7b6a0d83c03ff1 384 Gene3D G3DSA:3.40.47.10 258 370 1.2E-4 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS04245 db2ef3454b1af49bee7b6a0d83c03ff1 384 Gene3D G3DSA:3.40.47.10 189 221 9.0E-15 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS04245 db2ef3454b1af49bee7b6a0d83c03ff1 384 Gene3D G3DSA:3.40.47.10 14 113 9.0E-15 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS04245 db2ef3454b1af49bee7b6a0d83c03ff1 384 SUPERFAMILY SSF53901 7 222 6.72E-19 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS14955 6f9124013b4f9783241e80bd5a59d4ff 159 Pfam PF11292 Protein of unknown function (DUF3093) 12 157 3.8E-48 T 06-07-2017 IPR021443 Protein of unknown function DUF3093 CAK77_RS19435 5a7a301eb235056e529917639c36bb05 142 Gene3D G3DSA:3.30.1550.10 4 73 1.5E-37 T 06-07-2017 IPR020784 Ribosomal protein L11, N-terminal CAK77_RS19435 5a7a301eb235056e529917639c36bb05 142 Pfam PF03946 Ribosomal protein L11, N-terminal domain 11 68 1.6E-28 T 06-07-2017 IPR020784 Ribosomal protein L11, N-terminal CAK77_RS19435 5a7a301eb235056e529917639c36bb05 142 SUPERFAMILY SSF54747 4 74 5.76E-29 T 06-07-2017 IPR020784 Ribosomal protein L11, N-terminal CAK77_RS19435 5a7a301eb235056e529917639c36bb05 142 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 5 142 4.7E-62 T 06-07-2017 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS19435 5a7a301eb235056e529917639c36bb05 142 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 7 142 30.516 T 06-07-2017 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 CAK77_RS19435 5a7a301eb235056e529917639c36bb05 142 SMART SM00649 11 142 2.4E-85 T 06-07-2017 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 CAK77_RS19435 5a7a301eb235056e529917639c36bb05 142 Pfam PF00298 Ribosomal protein L11, RNA binding domain 73 141 9.6E-27 T 06-07-2017 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 CAK77_RS19435 5a7a301eb235056e529917639c36bb05 142 ProSitePatterns PS00359 Ribosomal protein L11 signature. 128 142 - T 06-07-2017 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK77_RS19435 5a7a301eb235056e529917639c36bb05 142 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 38 70 4.0E-13 T 06-07-2017 CAK77_RS19435 5a7a301eb235056e529917639c36bb05 142 SUPERFAMILY SSF46906 69 142 6.8E-27 T 06-07-2017 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 CAK77_RS19435 5a7a301eb235056e529917639c36bb05 142 Gene3D G3DSA:1.10.10.250 74 142 2.3E-33 T 06-07-2017 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 CAK77_RS02560 7e98285b30d9dd399b1f7cab68503227 930 Pfam PF13368 Topoisomerase C-terminal repeat 849 899 1.4E-19 T 06-07-2017 IPR025589 Topoisomerase C-terminal repeat CAK77_RS02560 7e98285b30d9dd399b1f7cab68503227 930 Pfam PF13368 Topoisomerase C-terminal repeat 635 696 8.9E-6 T 06-07-2017 IPR025589 Topoisomerase C-terminal repeat CAK77_RS02560 7e98285b30d9dd399b1f7cab68503227 930 Pfam PF13368 Topoisomerase C-terminal repeat 780 833 6.6E-17 T 06-07-2017 IPR025589 Topoisomerase C-terminal repeat CAK77_RS02560 7e98285b30d9dd399b1f7cab68503227 930 Pfam PF13368 Topoisomerase C-terminal repeat 702 775 9.9E-14 T 06-07-2017 IPR025589 Topoisomerase C-terminal repeat CAK77_RS02560 7e98285b30d9dd399b1f7cab68503227 930 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 4 654 3.9E-254 T 06-07-2017 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 CAK77_RS02560 7e98285b30d9dd399b1f7cab68503227 930 SMART SM00437 282 552 1.0E-125 T 06-07-2017 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 CAK77_RS02560 7e98285b30d9dd399b1f7cab68503227 930 Pfam PF01131 DNA topoisomerase 140 589 1.9E-119 T 06-07-2017 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CAK77_RS02560 7e98285b30d9dd399b1f7cab68503227 930 Hamap MF_00952 DNA topoisomerase 1 [topA]. 2 792 53.386 T 06-07-2017 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 CAK77_RS02560 7e98285b30d9dd399b1f7cab68503227 930 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 90 103 4.0E-34 T 06-07-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 CAK77_RS02560 7e98285b30d9dd399b1f7cab68503227 930 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 515 529 4.0E-34 T 06-07-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 CAK77_RS02560 7e98285b30d9dd399b1f7cab68503227 930 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 324 333 4.0E-34 T 06-07-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 CAK77_RS02560 7e98285b30d9dd399b1f7cab68503227 930 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 403 419 4.0E-34 T 06-07-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 CAK77_RS02560 7e98285b30d9dd399b1f7cab68503227 930 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 174 192 4.0E-34 T 06-07-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 CAK77_RS02560 7e98285b30d9dd399b1f7cab68503227 930 Pfam PF01751 Toprim domain 4 125 5.1E-28 T 06-07-2017 IPR006171 Toprim domain CAK77_RS02560 7e98285b30d9dd399b1f7cab68503227 930 Gene3D G3DSA:2.70.20.10 351 498 1.3E-32 T 06-07-2017 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 CAK77_RS02560 7e98285b30d9dd399b1f7cab68503227 930 Gene3D G3DSA:2.70.20.10 197 348 5.8E-26 T 06-07-2017 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 CAK77_RS02560 7e98285b30d9dd399b1f7cab68503227 930 Gene3D G3DSA:1.10.460.10 147 194 1.8E-50 T 06-07-2017 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 CAK77_RS02560 7e98285b30d9dd399b1f7cab68503227 930 Gene3D G3DSA:1.10.460.10 499 593 1.8E-50 T 06-07-2017 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 CAK77_RS02560 7e98285b30d9dd399b1f7cab68503227 930 SMART SM00493 2 116 4.0E-38 T 06-07-2017 IPR006171 Toprim domain CAK77_RS02560 7e98285b30d9dd399b1f7cab68503227 930 SUPERFAMILY SSF56712 2 222 3.53E-176 T 06-07-2017 IPR023405 DNA topoisomerase, type IA, core domain CAK77_RS02560 7e98285b30d9dd399b1f7cab68503227 930 SUPERFAMILY SSF56712 250 593 3.53E-176 T 06-07-2017 IPR023405 DNA topoisomerase, type IA, core domain CAK77_RS02560 7e98285b30d9dd399b1f7cab68503227 930 Gene3D G3DSA:3.40.50.140 3 146 5.6E-47 T 06-07-2017 IPR006171 Toprim domain CAK77_RS02560 7e98285b30d9dd399b1f7cab68503227 930 SMART SM00436 116 204 3.9E-45 T 06-07-2017 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 CAK77_RS02560 7e98285b30d9dd399b1f7cab68503227 930 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 319 333 - T 06-07-2017 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 CAK77_RS19685 c9c25ea98babebc2aca755959e19da4c 227 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 24 39 - T 06-07-2017 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 CAK77_RS19685 c9c25ea98babebc2aca755959e19da4c 227 Gene3D G3DSA:3.40.50.150 12 220 1.1E-42 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS19685 c9c25ea98babebc2aca755959e19da4c 227 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 4 227 33.164 T 06-07-2017 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 CAK77_RS19685 c9c25ea98babebc2aca755959e19da4c 227 Pfam PF01209 ubiE/COQ5 methyltransferase family 11 226 6.2E-59 T 06-07-2017 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 CAK77_RS19685 c9c25ea98babebc2aca755959e19da4c 227 SUPERFAMILY SSF53335 8 219 5.88E-41 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS19685 c9c25ea98babebc2aca755959e19da4c 227 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 13 226 2.1E-72 T 06-07-2017 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 CAK77_RS19685 c9c25ea98babebc2aca755959e19da4c 227 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 135 149 - T 06-07-2017 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 CAK77_RS04895 0d4d43b37cdf9ae40f34f452565d8821 170 SUPERFAMILY SSF54637 8 134 8.78E-32 T 06-07-2017 IPR029069 HotDog domain CAK77_RS04895 0d4d43b37cdf9ae40f34f452565d8821 170 Gene3D G3DSA:3.10.129.10 9 143 2.2E-38 T 06-07-2017 IPR029069 HotDog domain CAK77_RS04895 0d4d43b37cdf9ae40f34f452565d8821 170 Pfam PF03061 Thioesterase superfamily 53 115 4.1E-8 T 06-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 CAK77_RS01485 1677495a9af8d4dc8cfb9d9c20e5770d 401 Pfam PF01494 FAD binding domain 5 315 2.7E-20 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 CAK77_RS01485 1677495a9af8d4dc8cfb9d9c20e5770d 401 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 151 166 2.0E-12 T 06-07-2017 CAK77_RS01485 1677495a9af8d4dc8cfb9d9c20e5770d 401 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 298 314 2.0E-12 T 06-07-2017 CAK77_RS01485 1677495a9af8d4dc8cfb9d9c20e5770d 401 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 283 298 2.0E-12 T 06-07-2017 CAK77_RS01485 1677495a9af8d4dc8cfb9d9c20e5770d 401 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 2.0E-12 T 06-07-2017 CAK77_RS01485 1677495a9af8d4dc8cfb9d9c20e5770d 401 SUPERFAMILY SSF51905 3 172 4.37E-53 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS01485 1677495a9af8d4dc8cfb9d9c20e5770d 401 SUPERFAMILY SSF51905 270 357 4.37E-53 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS01485 1677495a9af8d4dc8cfb9d9c20e5770d 401 SUPERFAMILY SSF54373 177 276 8.24E-10 T 06-07-2017 CAK77_RS01485 1677495a9af8d4dc8cfb9d9c20e5770d 401 Gene3D G3DSA:3.50.50.60 281 318 1.4E-33 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS01485 1677495a9af8d4dc8cfb9d9c20e5770d 401 Gene3D G3DSA:3.50.50.60 3 175 1.4E-33 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS20510 6553f411d4e51be42b4ffbe3df96a5fb 289 SUPERFAMILY SSF48179 190 288 1.11E-28 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAK77_RS20510 6553f411d4e51be42b4ffbe3df96a5fb 289 Gene3D G3DSA:1.10.1040.10 192 287 7.3E-32 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAK77_RS20510 6553f411d4e51be42b4ffbe3df96a5fb 289 Gene3D G3DSA:3.40.50.720 5 191 1.2E-55 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS20510 6553f411d4e51be42b4ffbe3df96a5fb 289 PIRSF PIRSF000105 2 289 4.3E-80 T 06-07-2017 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 CAK77_RS20510 6553f411d4e51be42b4ffbe3df96a5fb 289 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 8 187 1.3E-58 T 06-07-2017 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 CAK77_RS20510 6553f411d4e51be42b4ffbe3df96a5fb 289 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 190 286 3.4E-31 T 06-07-2017 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 CAK77_RS20510 6553f411d4e51be42b4ffbe3df96a5fb 289 SUPERFAMILY SSF51735 5 187 1.6E-51 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS07195 31e83b94c64b058bbed537b5b957a23b 434 Gene3D G3DSA:3.30.70.260 351 420 4.4E-6 T 06-07-2017 CAK77_RS07195 31e83b94c64b058bbed537b5b957a23b 434 Pfam PF00742 Homoserine dehydrogenase 136 319 1.2E-65 T 06-07-2017 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CAK77_RS07195 31e83b94c64b058bbed537b5b957a23b 434 Gene3D G3DSA:3.40.50.720 3 147 3.5E-45 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS07195 31e83b94c64b058bbed537b5b957a23b 434 SUPERFAMILY SSF55347 136 306 1.9E-50 T 06-07-2017 CAK77_RS07195 31e83b94c64b058bbed537b5b957a23b 434 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 182 204 - T 06-07-2017 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CAK77_RS07195 31e83b94c64b058bbed537b5b957a23b 434 SUPERFAMILY SSF55021 349 424 4.2E-12 T 06-07-2017 CAK77_RS07195 31e83b94c64b058bbed537b5b957a23b 434 PIRSF PIRSF000098 2 432 2.0E-151 T 06-07-2017 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CAK77_RS07195 31e83b94c64b058bbed537b5b957a23b 434 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 11 128 6.9E-21 T 06-07-2017 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 CAK77_RS07195 31e83b94c64b058bbed537b5b957a23b 434 Gene3D G3DSA:3.30.360.10 148 303 1.8E-53 T 06-07-2017 CAK77_RS07195 31e83b94c64b058bbed537b5b957a23b 434 SUPERFAMILY SSF51735 2 157 1.56E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS07195 31e83b94c64b058bbed537b5b957a23b 434 Pfam PF01842 ACT domain 352 417 3.4E-11 T 06-07-2017 IPR002912 ACT domain GO:0008152|GO:0016597 CAK77_RS03515 69658eb125be31428d232adc2ad930df 297 Gene3D G3DSA:3.40.190.10 93 177 1.3E-4 T 06-07-2017 CAK77_RS03515 69658eb125be31428d232adc2ad930df 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 2.9E-13 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAK77_RS03515 69658eb125be31428d232adc2ad930df 297 Gene3D G3DSA:1.10.10.10 1 86 6.7E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS03515 69658eb125be31428d232adc2ad930df 297 Pfam PF03466 LysR substrate binding domain 87 291 6.8E-26 T 06-07-2017 IPR005119 LysR, substrate-binding CAK77_RS03515 69658eb125be31428d232adc2ad930df 297 Gene3D G3DSA:3.40.190.10 178 262 2.0E-23 T 06-07-2017 CAK77_RS03515 69658eb125be31428d232adc2ad930df 297 SUPERFAMILY SSF46785 1 110 1.29E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS03515 69658eb125be31428d232adc2ad930df 297 SUPERFAMILY SSF53850 89 292 1.3E-25 T 06-07-2017 CAK77_RS20500 d2bacc9f90fc0468c903dbc645cc7651 213 Pfam PF09347 Domain of unknown function (DUF1989) 19 185 1.9E-60 T 06-07-2017 IPR018959 Domain of unknown function DUF1989 CAK77_RS20500 d2bacc9f90fc0468c903dbc645cc7651 213 TIGRFAM TIGR03424 urea_degr_1: urea carboxylase-associated protein 1 15 210 2.1E-100 T 06-07-2017 IPR017791 Urea carboxylase-associated protein 1 CAK77_RS13810 95f1875ca83f6f3632d9d88eaa26ed90 105 SUPERFAMILY SSF46946 53 102 2.71E-5 T 06-07-2017 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 CAK77_RS13810 95f1875ca83f6f3632d9d88eaa26ed90 105 Gene3D G3DSA:1.10.8.50 50 100 1.2E-6 T 06-07-2017 CAK77_RS21915 ef07c76886dfcb1f73b6414b6c6423b7 237 Pfam PF02592 Putative vitamin uptake transporter 61 222 2.7E-42 T 06-07-2017 IPR003744 Protein of unknown function DUF165 CAK77_RS21915 ef07c76886dfcb1f73b6414b6c6423b7 237 TIGRFAM TIGR00697 TIGR00697: conserved hypothetical integral membrane protein 27 228 1.1E-30 T 06-07-2017 IPR003744 Protein of unknown function DUF165 CAK77_RS20350 166bdfcdb4fc3c2c8cd7b2eaa71f4e9a 454 Pfam PF03734 L,D-transpeptidase catalytic domain 246 366 5.1E-10 T 06-07-2017 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 CAK77_RS20350 166bdfcdb4fc3c2c8cd7b2eaa71f4e9a 454 Gene3D G3DSA:2.40.440.10 245 366 7.4E-13 T 06-07-2017 CAK77_RS20350 166bdfcdb4fc3c2c8cd7b2eaa71f4e9a 454 SUPERFAMILY SSF141523 245 366 1.7E-20 T 06-07-2017 CAK77_RS16210 bb399105c52a434d2ba90371f8cae221 178 Pfam PF02620 Uncharacterized ACR, COG1399 62 174 3.2E-27 T 06-07-2017 IPR003772 Protein of unknown function DUF177 CAK77_RS00400 acce404f78c956dd4847154778cc5700 510 SUPERFAMILY SSF140459 5 177 6.02E-60 T 06-07-2017 CAK77_RS00400 acce404f78c956dd4847154778cc5700 510 Pfam PF00823 PPE family 8 164 4.4E-57 T 06-07-2017 IPR000030 PPE family CAK77_RS10245 76c76cca32d352812fe64c6714979204 283 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 8 275 17.635 T 06-07-2017 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CAK77_RS10245 76c76cca32d352812fe64c6714979204 283 Pfam PF02673 Bacitracin resistance protein BacA 14 269 1.8E-72 T 06-07-2017 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CAK77_RS10245 76c76cca32d352812fe64c6714979204 283 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 13 268 1.4E-91 T 06-07-2017 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CAK77_RS03300 215e8426469f12b24f12831510e198c6 295 TIGRFAM TIGR00473 pssA: CDP-diacylglycerol-serine O-phosphatidyltransferase 21 186 1.3E-31 T 06-07-2017 IPR004533 CDP-diacylglycerol--serine O-phosphatidyltransferase KEGG: 00260+2.7.8.8|KEGG: 00564+2.7.8.8|MetaCyc: PWY-5669 CAK77_RS03300 215e8426469f12b24f12831510e198c6 295 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 57 79 - T 06-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CAK77_RS03300 215e8426469f12b24f12831510e198c6 295 Pfam PF01066 CDP-alcohol phosphatidyltransferase 15 79 8.9E-11 T 06-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CAK77_RS04095 108fb979345510c2f7135c8d76456d87 165 Pfam PF08592 Domain of unknown function (DUF1772) 26 147 8.7E-9 T 06-07-2017 IPR013901 Protein of unknown function DUF1772 CAK77_RS05635 be334b69328e6203bd630dcbe9562c63 301 Gene3D G3DSA:3.40.630.30 168 295 1.6E-27 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS05635 be334b69328e6203bd630dcbe9562c63 301 Pfam PF00583 Acetyltransferase (GNAT) family 199 274 2.9E-12 T 06-07-2017 IPR000182 GNAT domain GO:0008080 CAK77_RS05635 be334b69328e6203bd630dcbe9562c63 301 SUPERFAMILY SSF46785 12 136 1.93E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS05635 be334b69328e6203bd630dcbe9562c63 301 SUPERFAMILY SSF55729 163 294 7.77E-25 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS05635 be334b69328e6203bd630dcbe9562c63 301 Pfam PF12802 MarR family 33 87 2.0E-10 T 06-07-2017 CAK77_RS05635 be334b69328e6203bd630dcbe9562c63 301 Gene3D G3DSA:1.10.10.10 10 137 7.6E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS05635 be334b69328e6203bd630dcbe9562c63 301 SMART SM00347 25 124 0.0028 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK77_RS14560 b46a51b41e92251be1bd20be55f698e3 638 Pfam PF06259 Alpha/beta hydrolase 336 517 2.7E-50 T 06-07-2017 IPR010427 Protein of unknown function DUF1023 CAK77_RS14560 b46a51b41e92251be1bd20be55f698e3 638 Gene3D G3DSA:1.10.287.1060 12 94 2.3E-4 T 06-07-2017 CAK77_RS16120 ca3924fccba48f4f181415930cb631d6 461 Gene3D G3DSA:1.10.3430.10 3 421 1.1E-132 T 06-07-2017 IPR029020 Ammonium/urea transporter CAK77_RS16120 ca3924fccba48f4f181415930cb631d6 461 TIGRFAM TIGR00836 amt: ammonium transporter 8 440 9.1E-140 T 06-07-2017 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 CAK77_RS16120 ca3924fccba48f4f181415930cb631d6 461 Pfam PF00909 Ammonium Transporter Family 10 440 9.7E-130 T 06-07-2017 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 CAK77_RS16120 ca3924fccba48f4f181415930cb631d6 461 ProSitePatterns PS01219 Ammonium transporters signature. 191 216 - T 06-07-2017 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 CAK77_RS16120 ca3924fccba48f4f181415930cb631d6 461 SUPERFAMILY SSF111352 5 421 1.14E-117 T 06-07-2017 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 CAK77_RS12100 a808e684062a69b85393a4eea1e2e4d9 295 SUPERFAMILY SSF52402 9 149 9.21E-27 T 06-07-2017 CAK77_RS12100 a808e684062a69b85393a4eea1e2e4d9 295 Pfam PF00582 Universal stress protein family 8 146 1.4E-22 T 06-07-2017 IPR006016 UspA GO:0006950 CAK77_RS12100 a808e684062a69b85393a4eea1e2e4d9 295 Pfam PF00582 Universal stress protein family 156 292 2.9E-29 T 06-07-2017 IPR006016 UspA GO:0006950 CAK77_RS12100 a808e684062a69b85393a4eea1e2e4d9 295 SUPERFAMILY SSF52402 155 293 2.76E-34 T 06-07-2017 CAK77_RS12100 a808e684062a69b85393a4eea1e2e4d9 295 Gene3D G3DSA:3.40.50.620 141 293 1.8E-41 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS12100 a808e684062a69b85393a4eea1e2e4d9 295 PRINTS PR01438 Universal stress protein signature 7 25 4.0E-14 T 06-07-2017 IPR006015 Universal stress protein A CAK77_RS12100 a808e684062a69b85393a4eea1e2e4d9 295 PRINTS PR01438 Universal stress protein signature 253 265 4.0E-14 T 06-07-2017 IPR006015 Universal stress protein A CAK77_RS12100 a808e684062a69b85393a4eea1e2e4d9 295 PRINTS PR01438 Universal stress protein signature 271 293 4.0E-14 T 06-07-2017 IPR006015 Universal stress protein A CAK77_RS12100 a808e684062a69b85393a4eea1e2e4d9 295 Gene3D G3DSA:3.40.50.620 8 140 2.1E-28 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS01160 a32d382d1e6641c0cd0e228cca94b365 497 SUPERFAMILY SSF111331 214 495 2.22E-54 T 06-07-2017 IPR016064 NAD kinase/diacylglycerol kinase-like domain CAK77_RS01160 a32d382d1e6641c0cd0e228cca94b365 497 Gene3D G3DSA:1.20.144.10 20 185 3.1E-30 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CAK77_RS01160 a32d382d1e6641c0cd0e228cca94b365 497 SUPERFAMILY SSF48317 18 190 1.31E-32 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CAK77_RS01160 a32d382d1e6641c0cd0e228cca94b365 497 Pfam PF01569 PAP2 superfamily 79 188 2.2E-16 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CAK77_RS01160 a32d382d1e6641c0cd0e228cca94b365 497 Gene3D G3DSA:3.40.50.10330 255 324 5.7E-5 T 06-07-2017 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 CAK77_RS01160 a32d382d1e6641c0cd0e228cca94b365 497 SMART SM00046 214 328 3.1E-9 T 06-07-2017 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CAK77_RS01160 a32d382d1e6641c0cd0e228cca94b365 497 SMART SM00014 76 185 2.9E-13 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CAK77_RS01160 a32d382d1e6641c0cd0e228cca94b365 497 Pfam PF00781 Diacylglycerol kinase catalytic domain 215 328 1.0E-19 T 06-07-2017 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CAK77_RS20265 2deb362837f0d65059eea4be7dd1bd13 447 Gene3D G3DSA:3.90.1200.10 268 304 4.6E-5 T 06-07-2017 CAK77_RS20265 2deb362837f0d65059eea4be7dd1bd13 447 Gene3D G3DSA:3.30.200.20 123 200 7.4E-4 T 06-07-2017 CAK77_RS20265 2deb362837f0d65059eea4be7dd1bd13 447 Pfam PF03109 ABC1 family 117 220 1.5E-25 T 06-07-2017 IPR004147 UbiB domain CAK77_RS20265 2deb362837f0d65059eea4be7dd1bd13 447 SUPERFAMILY SSF56112 184 316 2.02E-21 T 06-07-2017 IPR011009 Protein kinase-like domain CAK77_RS20265 2deb362837f0d65059eea4be7dd1bd13 447 SUPERFAMILY SSF56112 94 152 2.02E-21 T 06-07-2017 IPR011009 Protein kinase-like domain CAK77_RS14960 6ebc9602bf4f067c36f49f1232ac3dd5 100 Pfam PF13834 Domain of unknown function (DUF4193) 1 99 1.6E-46 T 06-07-2017 IPR025242 Protein of unknown function DUF4193 CAK77_RS05110 e210e19998b4364bd5503d7d6d9a7424 432 Pfam PF01943 Polysaccharide biosynthesis protein 18 281 2.5E-16 T 06-07-2017 IPR002797 Polysaccharide biosynthesis protein GO:0016020 CAK77_RS17440 33902604e2ff383a4afcbcb540446d11 453 SUPERFAMILY SSF51971 260 323 1.02E-54 T 06-07-2017 CAK77_RS17440 33902604e2ff383a4afcbcb540446d11 453 SUPERFAMILY SSF51971 4 212 1.02E-54 T 06-07-2017 CAK77_RS17440 33902604e2ff383a4afcbcb540446d11 453 PRINTS PR00419 Adrenodoxin reductase family signature 146 160 6.7E-19 T 06-07-2017 CAK77_RS17440 33902604e2ff383a4afcbcb540446d11 453 PRINTS PR00419 Adrenodoxin reductase family signature 74 84 6.7E-19 T 06-07-2017 CAK77_RS17440 33902604e2ff383a4afcbcb540446d11 453 PRINTS PR00419 Adrenodoxin reductase family signature 5 27 6.7E-19 T 06-07-2017 CAK77_RS17440 33902604e2ff383a4afcbcb540446d11 453 PRINTS PR00419 Adrenodoxin reductase family signature 31 44 6.7E-19 T 06-07-2017 CAK77_RS17440 33902604e2ff383a4afcbcb540446d11 453 PRINTS PR00419 Adrenodoxin reductase family signature 213 226 6.7E-19 T 06-07-2017 CAK77_RS17440 33902604e2ff383a4afcbcb540446d11 453 Gene3D G3DSA:3.50.50.60 97 322 7.7E-70 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS17440 33902604e2ff383a4afcbcb540446d11 453 SUPERFAMILY SSF51971 304 449 1.88E-11 T 06-07-2017 CAK77_RS17440 33902604e2ff383a4afcbcb540446d11 453 PIRSF PIRSF000362 1 450 1.8E-153 T 06-07-2017 IPR021163 Ferredoxin-NADP+ reductase, adrenodoxin-type GO:0016491|GO:0055114 Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 CAK77_RS17440 33902604e2ff383a4afcbcb540446d11 453 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 183 5.2E-10 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS17440 33902604e2ff383a4afcbcb540446d11 453 Gene3D G3DSA:3.40.50.720 323 445 3.4E-72 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS17440 33902604e2ff383a4afcbcb540446d11 453 Gene3D G3DSA:3.40.50.720 5 96 3.4E-72 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS01235 e1567cb517c4f9c0d7f7b9d4aa05632b 96 SUPERFAMILY SSF51182 11 93 7.69E-7 T 06-07-2017 IPR011051 RmlC-like cupin domain CAK77_RS01235 e1567cb517c4f9c0d7f7b9d4aa05632b 96 Gene3D G3DSA:2.60.120.10 22 93 2.0E-8 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK77_RS24090 9afe41c0e703b3ffbcb3fa7a5c2bc2a0 165 SUPERFAMILY SSF50249 6 165 5.14E-48 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS24090 9afe41c0e703b3ffbcb3fa7a5c2bc2a0 165 Pfam PF00436 Single-strand binding protein family 6 106 2.9E-31 T 06-07-2017 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 CAK77_RS24090 9afe41c0e703b3ffbcb3fa7a5c2bc2a0 165 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 3 165 9.0E-35 T 06-07-2017 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 CAK77_RS24090 9afe41c0e703b3ffbcb3fa7a5c2bc2a0 165 Gene3D G3DSA:2.40.50.140 4 118 4.6E-42 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS24090 9afe41c0e703b3ffbcb3fa7a5c2bc2a0 165 Hamap MF_00984 Single-stranded DNA-binding protein. 4 113 32.057 T 06-07-2017 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 CAK77_RS06395 41a49fc36bc5ec21e3fe7b4b09045d75 606 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK77_RS06395 41a49fc36bc5ec21e3fe7b4b09045d75 606 Pfam PF00005 ABC transporter 29 162 7.1E-23 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK77_RS06395 41a49fc36bc5ec21e3fe7b4b09045d75 606 Pfam PF00005 ABC transporter 323 456 3.8E-22 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK77_RS06395 41a49fc36bc5ec21e3fe7b4b09045d75 606 SUPERFAMILY SSF52540 295 503 5.81E-42 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS06395 41a49fc36bc5ec21e3fe7b4b09045d75 606 SMART SM00382 38 219 3.1E-8 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS06395 41a49fc36bc5ec21e3fe7b4b09045d75 606 SMART SM00382 331 500 2.3E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS06395 41a49fc36bc5ec21e3fe7b4b09045d75 606 Gene3D G3DSA:3.40.50.300 304 521 4.4E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS06395 41a49fc36bc5ec21e3fe7b4b09045d75 606 Gene3D G3DSA:3.40.50.300 13 241 7.5E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS06395 41a49fc36bc5ec21e3fe7b4b09045d75 606 Pfam PF16326 ABC transporter C-terminal domain 542 603 1.4E-8 T 06-07-2017 IPR032524 ABC transporter Uup, C-terminal GO:0003677 CAK77_RS06395 41a49fc36bc5ec21e3fe7b4b09045d75 606 SUPERFAMILY SSF52540 13 224 2.41E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS19530 f78957857db26020118717a7d54ee952 600 Gene3D G3DSA:1.10.640.10 20 152 5.5E-104 T 06-07-2017 IPR019791 Haem peroxidase, animal CAK77_RS19530 f78957857db26020118717a7d54ee952 600 Gene3D G3DSA:1.10.640.10 187 575 5.5E-104 T 06-07-2017 IPR019791 Haem peroxidase, animal CAK77_RS19530 f78957857db26020118717a7d54ee952 600 PRINTS PR00457 Animal haem peroxidase signature 137 152 7.1E-12 T 06-07-2017 IPR019791 Haem peroxidase, animal CAK77_RS19530 f78957857db26020118717a7d54ee952 600 PRINTS PR00457 Animal haem peroxidase signature 285 311 7.1E-12 T 06-07-2017 IPR019791 Haem peroxidase, animal CAK77_RS19530 f78957857db26020118717a7d54ee952 600 PRINTS PR00457 Animal haem peroxidase signature 260 280 7.1E-12 T 06-07-2017 IPR019791 Haem peroxidase, animal CAK77_RS19530 f78957857db26020118717a7d54ee952 600 PRINTS PR00457 Animal haem peroxidase signature 486 506 7.1E-12 T 06-07-2017 IPR019791 Haem peroxidase, animal CAK77_RS19530 f78957857db26020118717a7d54ee952 600 SUPERFAMILY SSF48113 69 319 4.47E-128 T 06-07-2017 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 CAK77_RS19530 f78957857db26020118717a7d54ee952 600 SUPERFAMILY SSF48113 348 596 4.47E-128 T 06-07-2017 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 CAK77_RS19530 f78957857db26020118717a7d54ee952 600 Pfam PF03098 Animal haem peroxidase 72 574 3.7E-117 T 06-07-2017 IPR019791 Haem peroxidase, animal CAK77_RS23605 5b6bb89d627e7bde71de89e239a07bfa 386 Pfam PF01266 FAD dependent oxidoreductase 12 351 1.6E-36 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CAK77_RS23605 5b6bb89d627e7bde71de89e239a07bfa 386 Gene3D G3DSA:3.50.50.60 316 366 3.9E-31 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS23605 5b6bb89d627e7bde71de89e239a07bfa 386 Gene3D G3DSA:3.50.50.60 141 222 3.9E-31 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS23605 5b6bb89d627e7bde71de89e239a07bfa 386 Gene3D G3DSA:3.50.50.60 6 87 3.9E-31 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS23605 5b6bb89d627e7bde71de89e239a07bfa 386 SUPERFAMILY SSF51905 11 223 6.04E-33 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS23605 5b6bb89d627e7bde71de89e239a07bfa 386 SUPERFAMILY SSF51905 316 368 6.04E-33 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS08060 76c6aa4058649488debbfee8e8e21e45 389 Gene3D G3DSA:1.10.150.130 75 172 6.4E-4 T 06-07-2017 IPR023109 Integrase/recombinase, N-terminal CAK77_RS08060 76c6aa4058649488debbfee8e8e21e45 389 SUPERFAMILY SSF56349 75 368 1.74E-35 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CAK77_RS08060 76c6aa4058649488debbfee8e8e21e45 389 Gene3D G3DSA:1.10.443.10 178 368 4.9E-19 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAK77_RS08060 76c6aa4058649488debbfee8e8e21e45 389 Pfam PF00589 Phage integrase family 205 369 2.7E-12 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAK77_RS05215 1318fa8fe7a37398ba71de801dd72560 304 SUPERFAMILY SSF47240 30 227 2.86E-13 T 06-07-2017 IPR009078 Ferritin-like superfamily CAK77_RS05215 1318fa8fe7a37398ba71de801dd72560 304 Pfam PF11583 P-aminobenzoate N-oxygenase AurF 13 287 2.7E-96 T 06-07-2017 IPR025859 P-aminobenzoate N-oxygenase AurF CAK77_RS21065 c95381169b9677ac2949b78e5eedb20b 479 Gene3D G3DSA:3.40.309.10 266 449 4.1E-64 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAK77_RS21065 c95381169b9677ac2949b78e5eedb20b 479 Gene3D G3DSA:3.40.605.10 6 265 2.0E-87 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAK77_RS21065 c95381169b9677ac2949b78e5eedb20b 479 SUPERFAMILY SSF53720 6 475 9.82E-152 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAK77_RS21065 c95381169b9677ac2949b78e5eedb20b 479 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 279 290 - T 06-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CAK77_RS21065 c95381169b9677ac2949b78e5eedb20b 479 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 251 258 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CAK77_RS21065 c95381169b9677ac2949b78e5eedb20b 479 Pfam PF00171 Aldehyde dehydrogenase family 22 474 8.5E-152 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAK77_RS00980 43d2e2d3cce4edd233174b7773d128de 240 Gene3D G3DSA:3.90.1200.10 152 236 7.7E-22 T 06-07-2017 CAK77_RS00980 43d2e2d3cce4edd233174b7773d128de 240 Pfam PF01636 Phosphotransferase enzyme family 157 232 3.6E-10 T 06-07-2017 IPR002575 Aminoglycoside phosphotransferase CAK77_RS00980 43d2e2d3cce4edd233174b7773d128de 240 Gene3D G3DSA:3.30.200.20 10 91 1.3E-9 T 06-07-2017 CAK77_RS00980 43d2e2d3cce4edd233174b7773d128de 240 SUPERFAMILY SSF56112 13 235 2.62E-32 T 06-07-2017 IPR011009 Protein kinase-like domain CAK77_RS20365 3e2bf25d8a488904d5cd52f28f27ac52 411 Pfam PF07690 Major Facilitator Superfamily 10 321 1.6E-28 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK77_RS20365 3e2bf25d8a488904d5cd52f28f27ac52 411 SUPERFAMILY SSF103473 4 388 8.5E-48 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK77_RS20365 3e2bf25d8a488904d5cd52f28f27ac52 411 Gene3D G3DSA:1.20.1250.20 212 387 8.0E-14 T 06-07-2017 CAK77_RS20365 3e2bf25d8a488904d5cd52f28f27ac52 411 Gene3D G3DSA:1.20.1250.20 5 179 1.5E-21 T 06-07-2017 CAK77_RS01625 7d4029be6bd8bdad24f3d43c3a614394 114 Pfam PF02575 YbaB/EbfC DNA-binding family 14 102 1.3E-29 T 06-07-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family CAK77_RS01625 7d4029be6bd8bdad24f3d43c3a614394 114 Gene3D G3DSA:3.30.1310.10 4 111 5.6E-35 T 06-07-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family CAK77_RS01625 7d4029be6bd8bdad24f3d43c3a614394 114 SUPERFAMILY SSF82607 14 103 1.57E-25 T 06-07-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family CAK77_RS01625 7d4029be6bd8bdad24f3d43c3a614394 114 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 8 93 1.2E-21 T 06-07-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family CAK77_RS01625 7d4029be6bd8bdad24f3d43c3a614394 114 PIRSF PIRSF004555 5 114 1.3E-32 T 06-07-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family CAK77_RS01625 7d4029be6bd8bdad24f3d43c3a614394 114 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 7 101 20.099 T 06-07-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family CAK77_RS12815 9d2a9d23488bce132811caf0f36fef78 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 35 8.9E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS12815 9d2a9d23488bce132811caf0f36fef78 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 66 8.9E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS12815 9d2a9d23488bce132811caf0f36fef78 209 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 67 1.6E-15 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS12815 9d2a9d23488bce132811caf0f36fef78 209 Gene3D G3DSA:1.10.357.10 20 207 2.0E-27 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS12815 9d2a9d23488bce132811caf0f36fef78 209 SUPERFAMILY SSF46689 15 85 4.79E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS11620 c2da1e0f62072cc81b8fe42b087e3d20 506 Pfam PF03109 ABC1 family 158 278 2.6E-33 T 06-07-2017 IPR004147 UbiB domain CAK77_RS11620 c2da1e0f62072cc81b8fe42b087e3d20 506 SUPERFAMILY SSF56112 142 204 3.24E-30 T 06-07-2017 IPR011009 Protein kinase-like domain CAK77_RS11620 c2da1e0f62072cc81b8fe42b087e3d20 506 SUPERFAMILY SSF56112 238 359 3.24E-30 T 06-07-2017 IPR011009 Protein kinase-like domain CAK77_RS11620 c2da1e0f62072cc81b8fe42b087e3d20 506 Gene3D G3DSA:3.90.1200.10 297 361 6.7E-9 T 06-07-2017 CAK77_RS22880 eb7f807402544460ba65dd07299ddf50 346 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 24 296 1.0E-57 T 06-07-2017 IPR005693 Virulence factor Mce protein CAK77_RS22880 eb7f807402544460ba65dd07299ddf50 346 Pfam PF02470 MlaD protein 47 120 2.4E-15 T 06-07-2017 IPR003399 Mce/MlaD CAK77_RS01400 8ea8301537d032303befd36dab507ade 406 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 4 398 46.11 T 06-07-2017 IPR004803 Queuine tRNA-ribosyltransferase GO:0008033|GO:0008479|GO:0008616 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CAK77_RS01400 8ea8301537d032303befd36dab507ade 406 Gene3D G3DSA:3.20.20.105 5 405 7.9E-144 T 06-07-2017 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CAK77_RS01400 8ea8301537d032303befd36dab507ade 406 SUPERFAMILY SSF51713 6 404 9.68E-130 T 06-07-2017 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CAK77_RS01400 8ea8301537d032303befd36dab507ade 406 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 16 404 9.2E-123 T 06-07-2017 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CAK77_RS01400 8ea8301537d032303befd36dab507ade 406 Pfam PF01702 Queuine tRNA-ribosyltransferase 157 399 2.4E-80 T 06-07-2017 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CAK77_RS01400 8ea8301537d032303befd36dab507ade 406 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 17 404 1.9E-126 T 06-07-2017 IPR004803 Queuine tRNA-ribosyltransferase GO:0008033|GO:0008479|GO:0008616 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CAK77_RS00355 12302d3fe637943cb8c83b93b3251b8d 459 Pfam PF00498 FHA domain 388 450 3.6E-15 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CAK77_RS00355 12302d3fe637943cb8c83b93b3251b8d 459 SUPERFAMILY SSF49879 350 458 2.1E-28 T 06-07-2017 IPR008984 SMAD/FHA domain GO:0005515 CAK77_RS00355 12302d3fe637943cb8c83b93b3251b8d 459 Gene3D G3DSA:2.60.200.20 364 457 1.5E-26 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CAK77_RS00355 12302d3fe637943cb8c83b93b3251b8d 459 SMART SM00240 386 436 1.7E-11 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CAK77_RS00355 12302d3fe637943cb8c83b93b3251b8d 459 Pfam PF12401 Protein of unknown function (DUF2662) 4 118 5.1E-38 T 06-07-2017 IPR022128 Protein of unknown function DUF3662 CAK77_RS16435 a4f67be624eaa14adcc72aca2458cd4f 258 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 59 254 1.5E-66 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAK77_RS16435 a4f67be624eaa14adcc72aca2458cd4f 258 SUPERFAMILY SSF56529 50 254 1.57E-77 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAK77_RS16435 a4f67be624eaa14adcc72aca2458cd4f 258 Pfam PF10370 Domain of unknown function (DUF2437) 1 54 1.3E-14 T 06-07-2017 IPR018833 Domain of unknown function DUF2437 CAK77_RS16435 a4f67be624eaa14adcc72aca2458cd4f 258 Gene3D G3DSA:3.90.850.10 50 256 1.8E-88 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAK77_RS00470 98e7bfe62c33da5edf93640702d284eb 127 TIGRFAM TIGR04529 MTB_hemophore: hemophore-related protein, Rv0203/Rv1174c family 35 110 3.6E-20 T 06-07-2017 IPR032407 Haemophore, haem-binding GO:0020037 CAK77_RS00470 98e7bfe62c33da5edf93640702d284eb 127 Pfam PF16525 Haemophore, haem-binding 33 109 3.6E-24 T 06-07-2017 IPR032407 Haemophore, haem-binding GO:0020037 CAK77_RS22495 f2e8188c6db08e728e4395abf1fad80c 222 SMART SM00421 158 215 7.1E-24 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK77_RS22495 f2e8188c6db08e728e4395abf1fad80c 222 SMART SM00448 10 122 1.5E-24 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK77_RS22495 f2e8188c6db08e728e4395abf1fad80c 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 191 203 1.6E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK77_RS22495 f2e8188c6db08e728e4395abf1fad80c 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 161 175 1.6E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK77_RS22495 f2e8188c6db08e728e4395abf1fad80c 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 175 191 1.6E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK77_RS22495 f2e8188c6db08e728e4395abf1fad80c 222 SUPERFAMILY SSF52172 9 133 9.82E-28 T 06-07-2017 IPR011006 CheY-like superfamily CAK77_RS22495 f2e8188c6db08e728e4395abf1fad80c 222 SUPERFAMILY SSF46894 147 220 9.52E-23 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAK77_RS22495 f2e8188c6db08e728e4395abf1fad80c 222 ProSitePatterns PS00622 LuxR-type HTH domain signature. 175 202 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK77_RS22495 f2e8188c6db08e728e4395abf1fad80c 222 Gene3D G3DSA:1.10.10.10 127 220 2.5E-31 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS22495 f2e8188c6db08e728e4395abf1fad80c 222 Pfam PF00072 Response regulator receiver domain 12 123 8.4E-21 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK77_RS22495 f2e8188c6db08e728e4395abf1fad80c 222 Gene3D G3DSA:3.40.50.2300 9 126 2.1E-29 T 06-07-2017 CAK77_RS22495 f2e8188c6db08e728e4395abf1fad80c 222 Pfam PF00196 Bacterial regulatory proteins, luxR family 160 215 1.6E-19 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAK77_RS11035 ce1885d72da3482b7aa23be507a57ec1 402 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 53 390 1.4E-65 T 06-07-2017 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 CAK77_RS11035 ce1885d72da3482b7aa23be507a57ec1 402 Pfam PF04261 Dyp-type peroxidase family 53 390 1.2E-72 T 06-07-2017 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 CAK77_RS11035 ce1885d72da3482b7aa23be507a57ec1 402 SUPERFAMILY SSF54909 48 396 4.47E-82 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAK77_RS06760 b41ab8d1ec93478032cade629940d8c5 104 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 49 81 7.6E-12 T 06-07-2017 IPR019933 DivIVA domain CAK77_RS00890 ddd79abf294748957f8864e80bd2b67a 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 3.4E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS00890 ddd79abf294748957f8864e80bd2b67a 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 3.4E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS00890 ddd79abf294748957f8864e80bd2b67a 210 Gene3D G3DSA:1.10.357.10 11 204 2.9E-25 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS00890 ddd79abf294748957f8864e80bd2b67a 210 SUPERFAMILY SSF46689 9 85 8.72E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS00890 ddd79abf294748957f8864e80bd2b67a 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 67 5.5E-13 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS23665 5747d9622b7c3ee78b5f4277ed9c4d9a 255 Gene3D G3DSA:3.40.50.720 2 198 2.9E-45 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS23665 5747d9622b7c3ee78b5f4277ed9c4d9a 255 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK77_RS23665 5747d9622b7c3ee78b5f4277ed9c4d9a 255 Pfam PF00106 short chain dehydrogenase 7 193 1.0E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS23665 5747d9622b7c3ee78b5f4277ed9c4d9a 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.6E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS23665 5747d9622b7c3ee78b5f4277ed9c4d9a 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 1.6E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS23665 5747d9622b7c3ee78b5f4277ed9c4d9a 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 1.6E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS23665 5747d9622b7c3ee78b5f4277ed9c4d9a 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 1.6E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS23665 5747d9622b7c3ee78b5f4277ed9c4d9a 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 1.6E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS23665 5747d9622b7c3ee78b5f4277ed9c4d9a 255 SUPERFAMILY SSF51735 1 217 1.09E-42 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS10760 ef4df33bb6a04f83eba345b21381cf5b 111 Hamap MF_01483 RNA polymerase-binding protein RbpA [rbpA]. 16 111 21.742 T 06-07-2017 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 CAK77_RS10760 ef4df33bb6a04f83eba345b21381cf5b 111 Pfam PF13397 RNA polymerase-binding protein 4 105 1.5E-39 T 06-07-2017 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 CAK77_RS10345 016970e78ffdb064c1f0497aaa41f6f3 293 PIRSF PIRSF028754 2 292 2.4E-119 T 06-07-2017 IPR008492 Protein of unknown function DUF774 CAK77_RS10345 016970e78ffdb064c1f0497aaa41f6f3 293 SUPERFAMILY SSF159659 10 263 3.01E-90 T 06-07-2017 CAK77_RS10345 016970e78ffdb064c1f0497aaa41f6f3 293 Pfam PF09754 PAC2 family 23 240 2.4E-52 T 06-07-2017 IPR019151 Proteasome assembly chaperone 2 CAK77_RS15360 61bf7e177917964a87f87dcefc368c6f 250 Pfam PF02511 Thymidylate synthase complementing protein 32 224 6.2E-56 T 06-07-2017 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 CAK77_RS15360 61bf7e177917964a87f87dcefc368c6f 250 TIGRFAM TIGR02170 thyX: thymidylate synthase, flavin-dependent 8 230 8.2E-64 T 06-07-2017 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 CAK77_RS15360 61bf7e177917964a87f87dcefc368c6f 250 SUPERFAMILY SSF69796 33 235 2.62E-61 T 06-07-2017 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 CAK77_RS15360 61bf7e177917964a87f87dcefc368c6f 250 Hamap MF_01408 Thymidylate synthase ThyX [thyX]. 7 238 28.126 T 06-07-2017 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 CAK77_RS04450 5d2b99c865d45b6d729c97150bf49c15 153 Gene3D G3DSA:3.30.530.20 7 152 1.2E-21 T 06-07-2017 IPR023393 START-like domain CAK77_RS04450 5d2b99c865d45b6d729c97150bf49c15 153 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 8 151 2.5E-17 T 06-07-2017 IPR019587 Polyketide cyclase/dehydrase CAK77_RS04450 5d2b99c865d45b6d729c97150bf49c15 153 SUPERFAMILY SSF55961 1 152 2.92E-21 T 06-07-2017 CAK77_RS23910 9c4babc3fb4706ec979fa079aede62e3 219 Pfam PF13649 Methyltransferase domain 42 136 7.5E-16 T 06-07-2017 CAK77_RS23910 9c4babc3fb4706ec979fa079aede62e3 219 SUPERFAMILY SSF53335 3 183 1.96E-31 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS23910 9c4babc3fb4706ec979fa079aede62e3 219 Gene3D G3DSA:3.40.50.150 19 187 2.9E-28 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS06685 d9439acfb8057f36acf0605d93741c1c 182 Pfam PF12867 DinB superfamily 10 172 6.4E-17 T 06-07-2017 IPR024775 DinB-like domain CAK77_RS06685 d9439acfb8057f36acf0605d93741c1c 182 SUPERFAMILY SSF109854 5 41 2.91E-15 T 06-07-2017 CAK77_RS06685 d9439acfb8057f36acf0605d93741c1c 182 SUPERFAMILY SSF109854 76 179 2.91E-15 T 06-07-2017 CAK77_RS16900 2a6817370eedec99b837af2fb2c96a35 158 Gene3D G3DSA:2.30.110.10 29 97 4.8E-4 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS16900 2a6817370eedec99b837af2fb2c96a35 158 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 35 126 2.2E-24 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CAK77_RS16900 2a6817370eedec99b837af2fb2c96a35 158 Pfam PF04075 Domain of unknown function (DUF385) 35 121 9.6E-17 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CAK77_RS12540 79177cbe650640d23d559a3c3b7f32f0 147 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 112 3.4E-10 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CAK77_RS12540 79177cbe650640d23d559a3c3b7f32f0 147 SUPERFAMILY SSF54593 5 119 2.82E-18 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK77_RS12540 79177cbe650640d23d559a3c3b7f32f0 147 Gene3D G3DSA:3.10.180.10 6 116 6.5E-18 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK77_RS09010 7c56dc49e465fdb3bde04490acf6d5af 195 Gene3D G3DSA:1.10.357.10 9 191 4.4E-43 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS09010 7c56dc49e465fdb3bde04490acf6d5af 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 65 3.6E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS09010 7c56dc49e465fdb3bde04490acf6d5af 195 SUPERFAMILY SSF48498 86 190 7.19E-15 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS09010 7c56dc49e465fdb3bde04490acf6d5af 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 4.3E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS09010 7c56dc49e465fdb3bde04490acf6d5af 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 4.3E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS09010 7c56dc49e465fdb3bde04490acf6d5af 195 SUPERFAMILY SSF46689 10 82 1.1E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS23825 5adf3a22d02406c942903e52d3a1b16c 265 Pfam PF08924 Domain of unknown function (DUF1906) 60 186 1.0E-26 T 06-07-2017 IPR015020 Protein of unknown function DUF1906 CAK77_RS23825 5adf3a22d02406c942903e52d3a1b16c 265 Gene3D G3DSA:3.20.20.80 61 225 4.2E-14 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAK77_RS23825 5adf3a22d02406c942903e52d3a1b16c 265 SUPERFAMILY SSF51445 61 220 5.69E-8 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily CAK77_RS19495 a7e3507b9b09f2f073919f35d33ccfdb 519 SUPERFAMILY SSF52540 331 500 2.9E-18 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS19495 a7e3507b9b09f2f073919f35d33ccfdb 519 Gene3D G3DSA:3.40.50.300 332 460 2.2E-23 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS19495 a7e3507b9b09f2f073919f35d33ccfdb 519 SUPERFAMILY SSF56112 14 293 1.86E-16 T 06-07-2017 IPR011009 Protein kinase-like domain CAK77_RS19495 a7e3507b9b09f2f073919f35d33ccfdb 519 Pfam PF13671 AAA domain 332 459 4.4E-19 T 06-07-2017 CAK77_RS13010 6959eec6c0299d46dccf7bd4e4fc52e5 419 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 71 396 1.9E-53 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAK77_RS13010 6959eec6c0299d46dccf7bd4e4fc52e5 419 PIRSF PIRSF001413 8 414 1.8E-158 T 06-07-2017 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CAK77_RS13010 6959eec6c0299d46dccf7bd4e4fc52e5 419 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 25 407 4.1E-183 T 06-07-2017 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CAK77_RS13010 6959eec6c0299d46dccf7bd4e4fc52e5 419 Gene3D G3DSA:3.40.50.1100 196 410 3.8E-94 T 06-07-2017 CAK77_RS13010 6959eec6c0299d46dccf7bd4e4fc52e5 419 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 99 113 - T 06-07-2017 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CAK77_RS13010 6959eec6c0299d46dccf7bd4e4fc52e5 419 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 20 409 51.773 T 06-07-2017 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CAK77_RS13010 6959eec6c0299d46dccf7bd4e4fc52e5 419 SUPERFAMILY SSF53686 21 408 1.23E-145 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAK77_RS13010 6959eec6c0299d46dccf7bd4e4fc52e5 419 Gene3D G3DSA:3.40.50.1100 117 195 1.0E-21 T 06-07-2017 CAK77_RS04325 dd2fbf86abbdfc0d722cd7cdcbc51445 399 SUPERFAMILY SSF56601 14 387 7.74E-72 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK77_RS04325 dd2fbf86abbdfc0d722cd7cdcbc51445 399 Gene3D G3DSA:3.40.710.10 250 388 1.8E-79 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK77_RS04325 dd2fbf86abbdfc0d722cd7cdcbc51445 399 Gene3D G3DSA:3.40.710.10 12 218 1.8E-79 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK77_RS04325 dd2fbf86abbdfc0d722cd7cdcbc51445 399 Pfam PF00144 Beta-lactamase 32 382 2.5E-68 T 06-07-2017 IPR001466 Beta-lactamase-related CAK77_RS02835 b72e9f6dbc6f36561ec4b933a2dcfd49 114 ProDom PD026347 LSR2-LIKE LSR2 ANTIGEN IMMUNE PRECURSOR RESPONSE SIGNAL PLASMID LYSYL GP61 1 110 2.0E-28 T 06-07-2017 IPR024412 Lsr2 CAK77_RS02835 b72e9f6dbc6f36561ec4b933a2dcfd49 114 Pfam PF11774 Lsr2 1 113 9.0E-44 T 06-07-2017 IPR024412 Lsr2 CAK77_RS10205 20ab3e64063f6b42ea3f0e74cf2887c7 548 SMART SM00857 5 158 1.5E-8 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CAK77_RS10205 20ab3e64063f6b42ea3f0e74cf2887c7 548 Pfam PF07508 Recombinase 195 322 1.3E-21 T 06-07-2017 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 CAK77_RS10205 20ab3e64063f6b42ea3f0e74cf2887c7 548 Gene3D G3DSA:3.40.50.1390 5 140 6.0E-5 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CAK77_RS10205 20ab3e64063f6b42ea3f0e74cf2887c7 548 Pfam PF00239 Resolvase, N terminal domain 6 153 7.9E-9 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CAK77_RS10205 20ab3e64063f6b42ea3f0e74cf2887c7 548 SUPERFAMILY SSF53041 4 154 2.49E-10 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CAK77_RS06165 90850d989800ea45686f541b475e0a03 313 SUPERFAMILY SSF53850 42 310 2.12E-56 T 06-07-2017 CAK77_RS06165 90850d989800ea45686f541b475e0a03 313 Gene3D G3DSA:3.40.190.10 261 311 2.2E-47 T 06-07-2017 CAK77_RS06165 90850d989800ea45686f541b475e0a03 313 Gene3D G3DSA:3.40.190.10 41 146 2.2E-47 T 06-07-2017 CAK77_RS06165 90850d989800ea45686f541b475e0a03 313 Gene3D G3DSA:3.40.190.120 147 248 1.2E-31 T 06-07-2017 CAK77_RS06165 90850d989800ea45686f541b475e0a03 313 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 41 305 1.0E-52 T 06-07-2017 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 CAK77_RS16655 46d637528b27093094e81d37e2de31f6 226 Gene3D G3DSA:2.40.10.10 122 202 1.4E-7 T 06-07-2017 CAK77_RS16655 46d637528b27093094e81d37e2de31f6 226 Gene3D G3DSA:2.40.10.10 33 111 2.3E-4 T 06-07-2017 CAK77_RS16655 46d637528b27093094e81d37e2de31f6 226 SUPERFAMILY SSF50494 33 213 3.53E-19 T 06-07-2017 IPR009003 Peptidase S1, PA clan CAK77_RS16655 46d637528b27093094e81d37e2de31f6 226 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 58 63 - T 06-07-2017 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 CAK77_RS16005 5d07c36ea312f7047bd3f14fc53794cd 80 Gene3D G3DSA:1.10.1470.10 14 65 1.2E-10 T 06-07-2017 IPR008462 CsbD-like CAK77_RS16005 5d07c36ea312f7047bd3f14fc53794cd 80 SUPERFAMILY SSF69047 14 66 8.5E-10 T 06-07-2017 IPR008462 CsbD-like CAK77_RS16005 5d07c36ea312f7047bd3f14fc53794cd 80 Pfam PF05532 CsbD-like 14 63 2.1E-14 T 06-07-2017 IPR008462 CsbD-like CAK77_RS04010 07fbe8c8350310c8beffca3aff6b6b1c 354 SUPERFAMILY SSF161098 76 343 2.09E-32 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS04010 07fbe8c8350310c8beffca3aff6b6b1c 354 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 52 348 3.1E-86 T 06-07-2017 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 CAK77_RS04010 07fbe8c8350310c8beffca3aff6b6b1c 354 Gene3D G3DSA:1.10.3720.10 66 348 5.7E-36 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS04010 07fbe8c8350310c8beffca3aff6b6b1c 354 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 134 347 5.4E-17 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS20250 7f359f204d70a09297bd86d617f42b28 514 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 172 197 4.9E-7 T 06-07-2017 CAK77_RS20250 7f359f204d70a09297bd86d617f42b28 514 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 4.9E-7 T 06-07-2017 CAK77_RS20250 7f359f204d70a09297bd86d617f42b28 514 Gene3D G3DSA:3.50.50.60 385 468 2.5E-62 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS20250 7f359f204d70a09297bd86d617f42b28 514 Gene3D G3DSA:3.50.50.60 4 176 2.5E-62 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS20250 7f359f204d70a09297bd86d617f42b28 514 SUPERFAMILY SSF51905 297 419 3.24E-51 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS20250 7f359f204d70a09297bd86d617f42b28 514 SUPERFAMILY SSF51905 8 226 3.24E-51 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS20250 7f359f204d70a09297bd86d617f42b28 514 Gene3D G3DSA:3.50.50.60 177 205 2.4E-6 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS20250 7f359f204d70a09297bd86d617f42b28 514 Gene3D G3DSA:3.50.50.60 287 341 2.4E-6 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS20250 7f359f204d70a09297bd86d617f42b28 514 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 8 209 3.7E-17 T 06-07-2017 CAK77_RS20465 5fe98d1572ecf6b3eaee552ced68791e 447 Pfam PF04286 Protein of unknown function (DUF445) 83 445 1.4E-103 T 06-07-2017 IPR007383 Protein of unknown function DUF445 CAK77_RS08285 c6f86448770b0e12bba337a7b7f9f9dc 247 Gene3D G3DSA:3.40.50.1110 134 245 1.5E-9 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAK77_RS08285 c6f86448770b0e12bba337a7b7f9f9dc 247 Gene3D G3DSA:3.40.50.1110 11 93 1.5E-9 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAK77_RS08285 c6f86448770b0e12bba337a7b7f9f9dc 247 SUPERFAMILY SSF52266 180 240 1.67E-13 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAK77_RS08285 c6f86448770b0e12bba337a7b7f9f9dc 247 SUPERFAMILY SSF52266 11 138 1.67E-13 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAK77_RS15725 ee3ec653887b54b71dfa0cc33ea519a0 327 Gene3D G3DSA:3.40.50.1820 36 321 8.1E-24 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS15725 ee3ec653887b54b71dfa0cc33ea519a0 327 SUPERFAMILY SSF53474 189 323 1.77E-24 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS15725 ee3ec653887b54b71dfa0cc33ea519a0 327 SUPERFAMILY SSF53474 23 161 1.77E-24 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS15725 ee3ec653887b54b71dfa0cc33ea519a0 327 Pfam PF12146 Serine aminopeptidase, S33 43 170 6.8E-15 T 06-07-2017 IPR022742 Serine aminopeptidase, S33 CAK77_RS17770 d79185b17a16befb875e84d25ef655d3 326 SUPERFAMILY SSF52540 113 285 2.15E-36 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS17770 d79185b17a16befb875e84d25ef655d3 326 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 71 304 3.4E-38 T 06-07-2017 IPR004881 Ribosome biogenesis GTPase RsgA, putative GO:0003924|GO:0005525 CAK77_RS17770 d79185b17a16befb875e84d25ef655d3 326 Gene3D G3DSA:3.40.50.300 113 263 8.6E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS17770 d79185b17a16befb875e84d25ef655d3 326 Pfam PF03193 Protein of unknown function, DUF258 96 263 3.3E-40 T 06-07-2017 IPR010914 RsgA type GTPase domain GO:0003924|GO:0005525 CAK77_RS17770 d79185b17a16befb875e84d25ef655d3 326 Gene3D G3DSA:1.10.40.50 265 320 8.6E-7 T 06-07-2017 CAK77_RS16565 f5df85cfb096c2eb2b78ced6e1c38a13 268 Pfam PF07681 DoxX 103 185 1.2E-14 T 06-07-2017 IPR032808 DoxX family CAK77_RS18880 a0f1e9fb985aee07346e7ea4cfec9da8 443 Gene3D G3DSA:1.10.3370.10 2 443 3.8E-153 T 06-07-2017 IPR023201 SecY subunit domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CAK77_RS18880 a0f1e9fb985aee07346e7ea4cfec9da8 443 ProSitePatterns PS00756 Protein secY signature 2. 178 195 - T 06-07-2017 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CAK77_RS18880 a0f1e9fb985aee07346e7ea4cfec9da8 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 375 393 3.9E-100 T 06-07-2017 CAK77_RS18880 a0f1e9fb985aee07346e7ea4cfec9da8 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 115 138 3.9E-100 T 06-07-2017 CAK77_RS18880 a0f1e9fb985aee07346e7ea4cfec9da8 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 159 184 3.9E-100 T 06-07-2017 CAK77_RS18880 a0f1e9fb985aee07346e7ea4cfec9da8 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 18 36 3.9E-100 T 06-07-2017 CAK77_RS18880 a0f1e9fb985aee07346e7ea4cfec9da8 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 185 208 3.9E-100 T 06-07-2017 CAK77_RS18880 a0f1e9fb985aee07346e7ea4cfec9da8 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 74 94 3.9E-100 T 06-07-2017 CAK77_RS18880 a0f1e9fb985aee07346e7ea4cfec9da8 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 411 429 3.9E-100 T 06-07-2017 CAK77_RS18880 a0f1e9fb985aee07346e7ea4cfec9da8 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 320 342 3.9E-100 T 06-07-2017 CAK77_RS18880 a0f1e9fb985aee07346e7ea4cfec9da8 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 272 291 3.9E-100 T 06-07-2017 CAK77_RS18880 a0f1e9fb985aee07346e7ea4cfec9da8 443 Hamap MF_01465 Protein translocase subunit SecY [secY]. 5 442 28.671 T 06-07-2017 IPR026593 Protein translocase subunit SecY CAK77_RS18880 a0f1e9fb985aee07346e7ea4cfec9da8 443 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 15 438 1.5E-129 T 06-07-2017 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CAK77_RS18880 a0f1e9fb985aee07346e7ea4cfec9da8 443 Pfam PF00344 SecY translocase 75 426 2.9E-114 T 06-07-2017 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CAK77_RS18880 a0f1e9fb985aee07346e7ea4cfec9da8 443 SUPERFAMILY SSF103491 2 433 8.11E-121 T 06-07-2017 IPR023201 SecY subunit domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CAK77_RS18880 a0f1e9fb985aee07346e7ea4cfec9da8 443 ProSitePatterns PS00755 Protein secY signature 1. 75 94 - T 06-07-2017 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CAK77_RS18880 a0f1e9fb985aee07346e7ea4cfec9da8 443 PIRSF PIRSF004557 1 443 5.5E-117 T 06-07-2017 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CAK77_RS18930 443f0f97b52419e5aee7faa19a26bf2a 60 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 1 58 18.271 T 06-07-2017 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 CAK77_RS18930 443f0f97b52419e5aee7faa19a26bf2a 60 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 4 58 1.4E-20 T 06-07-2017 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 CAK77_RS18930 443f0f97b52419e5aee7faa19a26bf2a 60 Pfam PF00327 Ribosomal protein L30p/L7e 4 54 3.8E-19 T 06-07-2017 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain CAK77_RS18930 443f0f97b52419e5aee7faa19a26bf2a 60 PIRSF PIRSF002211 1 60 1.0E-26 T 06-07-2017 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 CAK77_RS18930 443f0f97b52419e5aee7faa19a26bf2a 60 Gene3D G3DSA:3.30.1390.20 1 59 5.5E-24 T 06-07-2017 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain CAK77_RS18930 443f0f97b52419e5aee7faa19a26bf2a 60 SUPERFAMILY SSF55129 1 59 2.35E-19 T 06-07-2017 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain CAK77_RS18930 443f0f97b52419e5aee7faa19a26bf2a 60 ProSitePatterns PS00634 Ribosomal protein L30 signature. 22 54 - T 06-07-2017 IPR018038 Ribosomal protein L30, conserved site CAK77_RS09635 f49dd04957fb18e8d49c44820a874149 423 SUPERFAMILY SSF52540 20 320 4.7E-35 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS09635 f49dd04957fb18e8d49c44820a874149 423 Gene3D G3DSA:3.40.50.300 17 320 2.9E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS09635 f49dd04957fb18e8d49c44820a874149 423 TIGRFAM TIGR00345 GET3_arsA_TRC40: transport-energizing ATPase, TRC40/GET3/ArsA family 21 325 6.3E-45 T 06-07-2017 IPR016300 Arsenical pump ATPase, ArsA/GET3 GO:0005524|GO:0016887 Reactome: R-HSA-381038 CAK77_RS09635 f49dd04957fb18e8d49c44820a874149 423 Pfam PF02374 Anion-transporting ATPase 21 326 5.6E-46 T 06-07-2017 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 CAK77_RS09810 1caa27c2219fa7fc86fb0e815d16e5eb 275 SUPERFAMILY SSF58113 117 245 1.06E-6 T 06-07-2017 CAK77_RS09810 1caa27c2219fa7fc86fb0e815d16e5eb 275 Pfam PF05103 DivIVA protein 3 64 7.3E-13 T 06-07-2017 IPR007793 DivIVA family CAK77_RS09810 1caa27c2219fa7fc86fb0e815d16e5eb 275 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 3 39 1.2E-14 T 06-07-2017 IPR019933 DivIVA domain CAK77_RS13910 82868a7c3920bcf1693a1e65ccbcb738 147 Pfam PF01478 Type IV leader peptidase family 10 108 8.6E-14 T 06-07-2017 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 CAK77_RS17245 3a05ca7413ce7373873ba797c50c3be6 508 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 370 451 1.5E-13 T 06-07-2017 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain CAK77_RS17245 3a05ca7413ce7373873ba797c50c3be6 508 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 83 263 5.3E-32 T 06-07-2017 IPR004474 Cell envelope-related transcriptional attenuator domain CAK77_RS17245 3a05ca7413ce7373873ba797c50c3be6 508 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 83 263 1.1E-23 T 06-07-2017 IPR004474 Cell envelope-related transcriptional attenuator domain CAK77_RS20625 dad8d9bc87f4c2acc6f203b60998907c 987 SUPERFAMILY SSF82866 735 944 1.57E-31 T 06-07-2017 CAK77_RS20625 dad8d9bc87f4c2acc6f203b60998907c 987 SUPERFAMILY SSF82866 167 364 1.83E-27 T 06-07-2017 CAK77_RS20625 dad8d9bc87f4c2acc6f203b60998907c 987 Gene3D G3DSA:1.20.1640.10 758 947 9.0E-27 T 06-07-2017 CAK77_RS20625 dad8d9bc87f4c2acc6f203b60998907c 987 Gene3D G3DSA:1.20.1640.10 163 375 2.2E-28 T 06-07-2017 CAK77_RS20625 dad8d9bc87f4c2acc6f203b60998907c 987 Pfam PF03176 MMPL family 620 951 1.2E-105 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 CAK77_RS20625 dad8d9bc87f4c2acc6f203b60998907c 987 Pfam PF03176 MMPL family 67 397 2.4E-109 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 CAK77_RS20625 dad8d9bc87f4c2acc6f203b60998907c 987 TIGRFAM TIGR00833 actII: transport protein 50 944 0.0 T 06-07-2017 IPR004707 Membrane transport protein MmpL family GO:0016021 CAK77_RS20645 f34eb00dc199ce9ca5e03fdacb09eb25 177 Pfam PF02627 Carboxymuconolactone decarboxylase family 48 99 5.8E-11 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CAK77_RS20645 f34eb00dc199ce9ca5e03fdacb09eb25 177 SUPERFAMILY SSF69118 5 176 3.8E-28 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAK77_RS20645 f34eb00dc199ce9ca5e03fdacb09eb25 177 Gene3D G3DSA:1.20.1290.10 40 176 3.3E-22 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAK77_RS01540 c1ac6b32f555744e7204aafbd3b693c4 174 ProDom PD008243 RV1792C/MT1741/MB1728C RV1945/MT1995 MB1980 MB0098C RV3466/MT3572 VERY RV1128C/MT1160 RV1148C/MT1183 MB1159C RV0095C 5 86 9.0E-7 T 06-07-2017 CAK77_RS01540 c1ac6b32f555744e7204aafbd3b693c4 174 Pfam PF02720 Domain of unknown function (DUF222) 29 174 1.1E-29 T 06-07-2017 IPR003870 Domain of unknown function DUF222 CAK77_RS01555 f5c130711bd9750102f372703cb3a3bc 427 SUPERFAMILY SSF53383 38 413 2.08E-42 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK77_RS01555 f5c130711bd9750102f372703cb3a3bc 427 Pfam PF12897 Alanine-glyoxylate amino-transferase 7 423 9.7E-195 T 06-07-2017 IPR024551 Aminotransferase, putative CAK77_RS01555 f5c130711bd9750102f372703cb3a3bc 427 Gene3D G3DSA:3.90.1150.10 2 166 5.2E-44 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK77_RS01555 f5c130711bd9750102f372703cb3a3bc 427 Gene3D G3DSA:3.90.1150.10 252 423 1.4E-56 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK77_RS24245 632bbf4c6fa582e56c0dec5173e27e3b 208 Gene3D G3DSA:3.40.1740.10 149 192 4.3E-24 T 06-07-2017 CAK77_RS24245 632bbf4c6fa582e56c0dec5173e27e3b 208 Gene3D G3DSA:3.40.1740.10 24 63 4.3E-24 T 06-07-2017 CAK77_RS24245 632bbf4c6fa582e56c0dec5173e27e3b 208 Pfam PF02622 Uncharacterized ACR, COG1678 37 191 6.8E-37 T 06-07-2017 IPR003774 Protein of unknown function UPF0301 CAK77_RS24245 632bbf4c6fa582e56c0dec5173e27e3b 208 SUPERFAMILY SSF143456 21 202 2.88E-46 T 06-07-2017 CAK77_RS24245 632bbf4c6fa582e56c0dec5173e27e3b 208 Hamap MF_00758 UPF0301 protein YqgE [yqgE]. 24 205 25.877 T 06-07-2017 IPR003774 Protein of unknown function UPF0301 CAK77_RS09205 a10e9e461bdf297873f27f84009c75ab 340 Pfam PF00155 Aminotransferase class I and II 42 325 8.8E-23 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAK77_RS09205 a10e9e461bdf297873f27f84009c75ab 340 Gene3D G3DSA:3.40.640.10 32 243 4.6E-46 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK77_RS09205 a10e9e461bdf297873f27f84009c75ab 340 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 198 211 - T 06-07-2017 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CAK77_RS09205 a10e9e461bdf297873f27f84009c75ab 340 Gene3D G3DSA:3.90.1150.10 256 340 3.2E-14 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK77_RS09205 a10e9e461bdf297873f27f84009c75ab 340 SUPERFAMILY SSF53383 18 339 1.22E-54 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK77_RS11815 e515beb225e2d6292d18c21d4487c522 273 SUPERFAMILY SSF53850 54 272 2.12E-48 T 06-07-2017 CAK77_RS11815 e515beb225e2d6292d18c21d4487c522 273 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 59 267 7.4E-29 T 06-07-2017 IPR005950 Molybdenum ABC transporter, periplasmic binding protein GO:0015412|GO:0015689|GO:0030288 CAK77_RS11815 e515beb225e2d6292d18c21d4487c522 273 PIRSF PIRSF004846 10 273 1.9E-55 T 06-07-2017 IPR005950 Molybdenum ABC transporter, periplasmic binding protein GO:0015412|GO:0015689|GO:0030288 CAK77_RS11815 e515beb225e2d6292d18c21d4487c522 273 Gene3D G3DSA:3.40.190.10 189 259 2.6E-6 T 06-07-2017 CAK77_RS11815 e515beb225e2d6292d18c21d4487c522 273 Pfam PF13531 Bacterial extracellular solute-binding protein 54 270 1.5E-37 T 06-07-2017 CAK77_RS11815 e515beb225e2d6292d18c21d4487c522 273 Gene3D G3DSA:3.40.190.10 52 180 1.2E-31 T 06-07-2017 CAK77_RS17860 e2e60d45bca2f9e3de1b543ea08da727 240 Pfam PF02308 MgtC family 11 132 1.6E-36 T 06-07-2017 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CAK77_RS17860 e2e60d45bca2f9e3de1b543ea08da727 240 PRINTS PR01837 MgtC/SapB protein signature 13 32 3.1E-42 T 06-07-2017 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CAK77_RS17860 e2e60d45bca2f9e3de1b543ea08da727 240 PRINTS PR01837 MgtC/SapB protein signature 32 50 3.1E-42 T 06-07-2017 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CAK77_RS17860 e2e60d45bca2f9e3de1b543ea08da727 240 PRINTS PR01837 MgtC/SapB protein signature 60 82 3.1E-42 T 06-07-2017 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CAK77_RS17860 e2e60d45bca2f9e3de1b543ea08da727 240 PRINTS PR01837 MgtC/SapB protein signature 87 111 3.1E-42 T 06-07-2017 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CAK77_RS09475 4dca519300a405f020ff4fc53db5f18d 570 Pfam PF10518 TAT (twin-arginine translocation) pathway signal sequence 43 62 2.3E-6 T 06-07-2017 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal CAK77_RS09475 4dca519300a405f020ff4fc53db5f18d 570 Pfam PF00149 Calcineurin-like phosphoesterase 234 439 3.4E-9 T 06-07-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 CAK77_RS09475 4dca519300a405f020ff4fc53db5f18d 570 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 43 70 3.6E-5 T 06-07-2017 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal CAK77_RS09475 4dca519300a405f020ff4fc53db5f18d 570 Gene3D G3DSA:3.60.21.10 192 564 1.9E-63 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAK77_RS09475 4dca519300a405f020ff4fc53db5f18d 570 SUPERFAMILY SSF56300 514 561 1.58E-39 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAK77_RS09475 4dca519300a405f020ff4fc53db5f18d 570 SUPERFAMILY SSF56300 192 486 1.58E-39 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAK77_RS22175 70711bdf6edd21b69a95fcda86b73cbf 372 SUPERFAMILY SSF53850 51 354 9.7E-66 T 06-07-2017 CAK77_RS22175 70711bdf6edd21b69a95fcda86b73cbf 372 Gene3D G3DSA:3.40.190.10 154 306 1.9E-55 T 06-07-2017 CAK77_RS22175 70711bdf6edd21b69a95fcda86b73cbf 372 TIGRFAM TIGR00971 3a0106s03: sulfate ABC transporter, sulfate-binding protein 50 353 2.0E-96 T 06-07-2017 IPR005669 Thiosulphate/Sulfate-binding protein GO:0008272|GO:0015419 CAK77_RS22175 70711bdf6edd21b69a95fcda86b73cbf 372 Gene3D G3DSA:3.40.190.10 71 153 1.4E-10 T 06-07-2017 CAK77_RS22175 70711bdf6edd21b69a95fcda86b73cbf 372 Pfam PF13531 Bacterial extracellular solute-binding protein 74 308 3.1E-39 T 06-07-2017 CAK77_RS12120 e6db0ec4fadacba51b7d52a5e38e03f1 273 Pfam PF04439 Streptomycin adenylyltransferase 5 249 2.2E-34 T 06-07-2017 IPR007530 Aminoglycoside 6-adenylyltransferase CAK77_RS12120 e6db0ec4fadacba51b7d52a5e38e03f1 273 SUPERFAMILY SSF81301 3 119 1.18E-23 T 06-07-2017 CAK77_RS12120 e6db0ec4fadacba51b7d52a5e38e03f1 273 Gene3D G3DSA:3.30.460.10 10 120 1.7E-20 T 06-07-2017 CAK77_RS12120 e6db0ec4fadacba51b7d52a5e38e03f1 273 SUPERFAMILY SSF81631 128 248 1.18E-27 T 06-07-2017 CAK77_RS12120 e6db0ec4fadacba51b7d52a5e38e03f1 273 Gene3D G3DSA:1.20.120.330 133 248 1.3E-13 T 06-07-2017 CAK77_RS04335 2dfdbe7bbddde6ac6492998ad4bdb5bc 1043 SUPERFAMILY SSF82866 132 353 1.83E-26 T 06-07-2017 CAK77_RS04335 2dfdbe7bbddde6ac6492998ad4bdb5bc 1043 Gene3D G3DSA:1.20.1640.10 188 357 3.0E-27 T 06-07-2017 CAK77_RS04335 2dfdbe7bbddde6ac6492998ad4bdb5bc 1043 Gene3D G3DSA:1.20.1640.10 782 988 6.9E-17 T 06-07-2017 CAK77_RS04335 2dfdbe7bbddde6ac6492998ad4bdb5bc 1043 Pfam PF03176 MMPL family 52 378 7.7E-93 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 CAK77_RS04335 2dfdbe7bbddde6ac6492998ad4bdb5bc 1043 Pfam PF03176 MMPL family 679 990 1.6E-86 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 CAK77_RS04335 2dfdbe7bbddde6ac6492998ad4bdb5bc 1043 SUPERFAMILY SSF82866 776 987 3.4E-24 T 06-07-2017 CAK77_RS04335 2dfdbe7bbddde6ac6492998ad4bdb5bc 1043 TIGRFAM TIGR00833 actII: transport protein 18 987 1.2E-273 T 06-07-2017 IPR004707 Membrane transport protein MmpL family GO:0016021 CAK77_RS09110 51bbc19ce4537c3469cc938e8ced6187 450 Pfam PF02515 CoA-transferase family III 198 379 3.8E-39 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 CAK77_RS09110 51bbc19ce4537c3469cc938e8ced6187 450 SUPERFAMILY SSF89796 197 379 2.62E-46 T 06-07-2017 IPR023606 CoA-transferase family III domain CAK77_RS09110 51bbc19ce4537c3469cc938e8ced6187 450 SUPERFAMILY SSF89796 50 195 2.88E-11 T 06-07-2017 IPR023606 CoA-transferase family III domain CAK77_RS09110 51bbc19ce4537c3469cc938e8ced6187 450 Gene3D G3DSA:3.40.50.10540 197 380 3.4E-56 T 06-07-2017 IPR023606 CoA-transferase family III domain CAK77_RS10655 190a331eab77c144ee614a5104186613 313 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 26 258 2.6E-72 T 06-07-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CAK77_RS10655 190a331eab77c144ee614a5104186613 313 Pfam PF00902 Sec-independent protein translocase protein (TatC) 28 251 3.5E-62 T 06-07-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CAK77_RS10655 190a331eab77c144ee614a5104186613 313 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 25 52 4.6E-41 T 06-07-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CAK77_RS10655 190a331eab77c144ee614a5104186613 313 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 118 136 4.6E-41 T 06-07-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CAK77_RS10655 190a331eab77c144ee614a5104186613 313 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 136 162 4.6E-41 T 06-07-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CAK77_RS10655 190a331eab77c144ee614a5104186613 313 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 186 214 4.6E-41 T 06-07-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CAK77_RS10655 190a331eab77c144ee614a5104186613 313 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 20 273 17.929 T 06-07-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CAK77_RS10655 190a331eab77c144ee614a5104186613 313 ProSitePatterns PS01218 TatC family signature. 186 205 - T 06-07-2017 IPR019820 Sec-independent periplasmic protein translocase, conserved site CAK77_RS18835 e89d61de79ef5693ac114aea7dbd428c 427 SUPERFAMILY SSF51905 20 194 4.65E-44 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS18835 e89d61de79ef5693ac114aea7dbd428c 427 SUPERFAMILY SSF51905 297 410 4.65E-44 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS18835 e89d61de79ef5693ac114aea7dbd428c 427 Pfam PF01494 FAD binding domain 19 342 1.9E-31 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 CAK77_RS18835 e89d61de79ef5693ac114aea7dbd428c 427 Gene3D G3DSA:3.30.9.10 185 225 7.9E-5 T 06-07-2017 CAK77_RS18835 e89d61de79ef5693ac114aea7dbd428c 427 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 316 332 1.6E-24 T 06-07-2017 CAK77_RS18835 e89d61de79ef5693ac114aea7dbd428c 427 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 301 316 1.6E-24 T 06-07-2017 CAK77_RS18835 e89d61de79ef5693ac114aea7dbd428c 427 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 173 188 1.6E-24 T 06-07-2017 CAK77_RS18835 e89d61de79ef5693ac114aea7dbd428c 427 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 19 41 1.6E-24 T 06-07-2017 CAK77_RS18835 e89d61de79ef5693ac114aea7dbd428c 427 Gene3D G3DSA:3.50.50.60 299 339 2.0E-41 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS18835 e89d61de79ef5693ac114aea7dbd428c 427 Gene3D G3DSA:3.50.50.60 20 184 2.0E-41 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS24455 93af374d1231273825067ef25e92ce62 638 SUPERFAMILY SSF56349 321 522 3.83E-32 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CAK77_RS24455 93af374d1231273825067ef25e92ce62 638 Gene3D G3DSA:1.10.443.10 324 517 3.0E-28 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAK77_RS24455 93af374d1231273825067ef25e92ce62 638 Pfam PF00589 Phage integrase family 337 511 2.1E-20 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAK77_RS12755 52bb24d436f6cbcb6e7aef7bc2accf39 245 SUPERFAMILY SSF51197 2 234 2.84E-54 T 06-07-2017 CAK77_RS12755 52bb24d436f6cbcb6e7aef7bc2accf39 245 Gene3D G3DSA:2.60.120.620 2 195 5.0E-34 T 06-07-2017 CAK77_RS12755 52bb24d436f6cbcb6e7aef7bc2accf39 245 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 3 180 2.2E-28 T 06-07-2017 IPR008775 Phytanoyl-CoA dioxygenase CAK77_RS22745 968bf0cc9202ebd1000982d73c9d0cb0 268 Pfam PF00378 Enoyl-CoA hydratase/isomerase 16 267 6.9E-52 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAK77_RS22745 968bf0cc9202ebd1000982d73c9d0cb0 268 SUPERFAMILY SSF52096 12 268 8.06E-70 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS22745 968bf0cc9202ebd1000982d73c9d0cb0 268 Gene3D G3DSA:3.90.226.10 12 268 4.2E-70 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS18480 e4551a973fa32bd805c317d06b6688d2 514 SUPERFAMILY SSF56672 1 224 3.91E-32 T 06-07-2017 CAK77_RS18480 e4551a973fa32bd805c317d06b6688d2 514 Pfam PF00817 impB/mucB/samB family 12 139 8.8E-13 T 06-07-2017 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CAK77_RS22475 c6ef94bd8dc0d0e7aa7317b6260f9adf 355 Pfam PF02470 MlaD protein 38 112 2.6E-16 T 06-07-2017 IPR003399 Mce/MlaD CAK77_RS22475 c6ef94bd8dc0d0e7aa7317b6260f9adf 355 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 14 268 1.0E-48 T 06-07-2017 IPR005693 Virulence factor Mce protein CAK77_RS07840 4461022fa6bc3f3c4ccb09e5c5fe8768 1156 Pfam PF13930 DNA/RNA non-specific endonuclease 1020 1142 1.7E-16 T 06-07-2017 CAK77_RS20665 03163f1ae06e4f4691bb3daf00791561 512 Pfam PF13520 Amino acid permease 51 437 4.1E-22 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CAK77_RS20665 03163f1ae06e4f4691bb3daf00791561 512 PIRSF PIRSF006060 3 480 8.7E-44 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CAK77_RS06140 c8f5faae1ebeff3662c24096bb1ad37e 506 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 184 199 - T 06-07-2017 IPR019826 Carboxylesterase type B, active site CAK77_RS06140 c8f5faae1ebeff3662c24096bb1ad37e 506 Pfam PF00135 Carboxylesterase family 10 488 8.4E-98 T 06-07-2017 IPR002018 Carboxylesterase, type B CAK77_RS06140 c8f5faae1ebeff3662c24096bb1ad37e 506 Gene3D G3DSA:3.40.50.1820 6 502 1.3E-126 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS06140 c8f5faae1ebeff3662c24096bb1ad37e 506 SUPERFAMILY SSF53474 9 501 6.49E-110 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS14695 f35acf40e4819bf64ec5cf4b79da3789 302 Pfam PF01435 Peptidase family M48 13 207 1.5E-29 T 06-07-2017 IPR001915 Peptidase M48 GO:0004222|GO:0006508 CAK77_RS14695 f35acf40e4819bf64ec5cf4b79da3789 302 Gene3D G3DSA:3.30.2010.10 6 93 9.9E-20 T 06-07-2017 CAK77_RS11580 2b0d212317d4a7103e03918113779ac8 250 Pfam PF01636 Phosphotransferase enzyme family 35 241 2.5E-22 T 06-07-2017 IPR002575 Aminoglycoside phosphotransferase CAK77_RS11580 2b0d212317d4a7103e03918113779ac8 250 Gene3D G3DSA:3.30.200.20 6 71 3.5E-13 T 06-07-2017 CAK77_RS11580 2b0d212317d4a7103e03918113779ac8 250 SUPERFAMILY SSF56112 8 246 1.46E-33 T 06-07-2017 IPR011009 Protein kinase-like domain CAK77_RS11580 2b0d212317d4a7103e03918113779ac8 250 Gene3D G3DSA:3.90.1200.10 72 247 6.2E-34 T 06-07-2017 CAK77_RS11580 2b0d212317d4a7103e03918113779ac8 250 PIRSF PIRSF000706 1 248 2.6E-62 T 06-07-2017 IPR024165 Aminoglycoside 3-phosphotransferase GO:0005524|GO:0016773|GO:0046677 CAK77_RS18295 5a0e16417ba8b6e283936dc853bd9117 140 Gene3D G3DSA:1.20.1300.10 18 129 2.8E-31 T 06-07-2017 CAK77_RS18295 5a0e16417ba8b6e283936dc853bd9117 140 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 17 124 3.5E-25 T 06-07-2017 IPR000701 Succinate dehydrogenase/Fumarate reductase, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK77_RS18295 5a0e16417ba8b6e283936dc853bd9117 140 TIGRFAM TIGR02970 succ_dehyd_cytB: succinate dehydrogenase, cytochrome b556 subunit 22 126 3.3E-29 T 06-07-2017 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK77_RS18295 5a0e16417ba8b6e283936dc853bd9117 140 SUPERFAMILY SSF81343 18 130 2.62E-28 T 06-07-2017 CAK77_RS11205 f06b8801c2b2e8929ccb7a379795a76b 997 SUPERFAMILY SSF82866 743 946 3.4E-26 T 06-07-2017 CAK77_RS11205 f06b8801c2b2e8929ccb7a379795a76b 997 SUPERFAMILY SSF82866 164 366 4.05E-26 T 06-07-2017 CAK77_RS11205 f06b8801c2b2e8929ccb7a379795a76b 997 TIGRFAM TIGR00833 actII: transport protein 25 946 8.7E-287 T 06-07-2017 IPR004707 Membrane transport protein MmpL family GO:0016021 CAK77_RS11205 f06b8801c2b2e8929ccb7a379795a76b 997 Gene3D G3DSA:1.20.1640.10 739 947 4.7E-22 T 06-07-2017 CAK77_RS11205 f06b8801c2b2e8929ccb7a379795a76b 997 Gene3D G3DSA:1.20.1640.10 162 370 3.7E-23 T 06-07-2017 CAK77_RS11205 f06b8801c2b2e8929ccb7a379795a76b 997 Pfam PF03176 MMPL family 58 398 5.9E-99 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 CAK77_RS11205 f06b8801c2b2e8929ccb7a379795a76b 997 Pfam PF03176 MMPL family 624 953 2.2E-90 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 CAK77_RS10490 964507b2499fc8102e0197ab4fe4ba4d 293 Pfam PF12705 PD-(D/E)XK nuclease superfamily 15 258 1.9E-38 T 06-07-2017 CAK77_RS10490 964507b2499fc8102e0197ab4fe4ba4d 293 SUPERFAMILY SSF52980 41 193 8.58E-10 T 06-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CAK77_RS04370 855bc5f80e95a1c8d65e854f63bdf801 745 Pfam PF13625 Helicase conserved C-terminal domain 473 594 1.1E-37 T 06-07-2017 IPR032830 Helicase XPB/Ssl2, N-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 CAK77_RS04495 8bd5189c63a5a410f8e4ea8d5a2e6253 101 Pfam PF02656 Domain of unknown function (DUF202) 5 69 1.2E-8 T 06-07-2017 IPR003807 Domain of unknown function DUF202 CAK77_RS14125 3c8f32b25ff82d89ba938e6fd076c688 203 SUPERFAMILY SSF48317 19 186 7.72E-18 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CAK77_RS14125 3c8f32b25ff82d89ba938e6fd076c688 203 Gene3D G3DSA:1.20.144.10 36 185 7.2E-13 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CAK77_RS14125 3c8f32b25ff82d89ba938e6fd076c688 203 Pfam PF01569 PAP2 superfamily 98 186 8.5E-10 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CAK77_RS09440 f5f078ce0a34642847fcefd9deec9fac 307 Gene3D G3DSA:3.40.50.720 4 240 2.0E-25 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS09440 f5f078ce0a34642847fcefd9deec9fac 307 TIGRFAM TIGR01777 yfcH: TIGR01777 family protein 10 297 6.2E-94 T 06-07-2017 IPR010099 Epimerase family protein SDR39U1 CAK77_RS09440 f5f078ce0a34642847fcefd9deec9fac 307 SUPERFAMILY SSF51735 8 261 8.92E-41 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS09440 f5f078ce0a34642847fcefd9deec9fac 307 Pfam PF08338 Domain of unknown function (DUF1731) 253 298 6.1E-14 T 06-07-2017 IPR013549 Domain of unknown function DUF1731 CAK77_RS09440 f5f078ce0a34642847fcefd9deec9fac 307 Pfam PF01370 NAD dependent epimerase/dehydratase family 10 219 1.4E-14 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 CAK77_RS00940 1ac6ec162e3badd423b51453185d55b0 152 Gene3D G3DSA:2.30.110.10 46 135 1.1E-4 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS00940 1ac6ec162e3badd423b51453185d55b0 152 Pfam PF04075 Domain of unknown function (DUF385) 29 147 9.4E-30 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CAK77_RS00940 1ac6ec162e3badd423b51453185d55b0 152 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 43 149 5.5E-28 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CAK77_RS08195 08fd47d734fc0a8cacc803ddc2f74f9e 478 SUPERFAMILY SSF53623 19 326 1.32E-84 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAK77_RS08195 08fd47d734fc0a8cacc803ddc2f74f9e 478 ProSitePatterns PS01012 Folylpolyglutamate synthase signature 2. 159 174 - T 06-07-2017 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 CAK77_RS08195 08fd47d734fc0a8cacc803ddc2f74f9e 478 Pfam PF08245 Mur ligase middle domain 59 302 2.6E-15 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAK77_RS08195 08fd47d734fc0a8cacc803ddc2f74f9e 478 Pfam PF02875 Mur ligase family, glutamate ligase domain 328 409 3.1E-12 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CAK77_RS08195 08fd47d734fc0a8cacc803ddc2f74f9e 478 SUPERFAMILY SSF53244 330 475 4.76E-25 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CAK77_RS08195 08fd47d734fc0a8cacc803ddc2f74f9e 478 Gene3D G3DSA:3.40.1190.10 29 326 6.0E-92 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAK77_RS08195 08fd47d734fc0a8cacc803ddc2f74f9e 478 Gene3D G3DSA:3.90.190.20 330 475 1.7E-37 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CAK77_RS08195 08fd47d734fc0a8cacc803ddc2f74f9e 478 PIRSF PIRSF001563 12 477 1.1E-106 T 06-07-2017 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 CAK77_RS08195 08fd47d734fc0a8cacc803ddc2f74f9e 478 TIGRFAM TIGR01499 folC: bifunctional protein FolC 38 471 8.5E-92 T 06-07-2017 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 CAK77_RS11805 e5605d972a32d8ba245e5a13ccc31e83 327 Gene3D G3DSA:3.20.20.30 3 326 1.3E-78 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS11805 e5605d972a32d8ba245e5a13ccc31e83 327 SUPERFAMILY SSF51679 3 326 3.18E-76 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS11805 e5605d972a32d8ba245e5a13ccc31e83 327 Pfam PF00296 Luciferase-like monooxygenase 5 298 3.6E-55 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS11805 e5605d972a32d8ba245e5a13ccc31e83 327 TIGRFAM TIGR03560 F420_Rv1855c: probable F420-dependent oxidoreductase, Rv1855c family 11 233 4.0E-89 T 06-07-2017 IPR019952 F420-dependent oxidoreductase-predicted, Rv1855c CAK77_RS05405 0535350953295c639fae5686f651c8bf 228 Gene3D G3DSA:1.10.10.10 125 225 4.8E-34 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS05405 0535350953295c639fae5686f651c8bf 228 Pfam PF00486 Transcriptional regulatory protein, C terminal 150 223 1.3E-24 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAK77_RS05405 0535350953295c639fae5686f651c8bf 228 SUPERFAMILY SSF46894 125 224 7.94E-30 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAK77_RS05405 0535350953295c639fae5686f651c8bf 228 SMART SM00448 1 112 2.2E-44 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK77_RS05405 0535350953295c639fae5686f651c8bf 228 Pfam PF00072 Response regulator receiver domain 3 112 1.3E-31 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK77_RS05405 0535350953295c639fae5686f651c8bf 228 SUPERFAMILY SSF52172 2 121 4.84E-43 T 06-07-2017 IPR011006 CheY-like superfamily CAK77_RS05405 0535350953295c639fae5686f651c8bf 228 Gene3D G3DSA:3.40.50.2300 2 123 2.0E-42 T 06-07-2017 CAK77_RS05405 0535350953295c639fae5686f651c8bf 228 SMART SM00862 148 223 2.0E-24 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAK77_RS15140 aec0a57fd910fa47e94d55b013380bb5 774 Gene3D G3DSA:3.40.50.740 57 154 1.6E-38 T 06-07-2017 CAK77_RS15140 aec0a57fd910fa47e94d55b013380bb5 774 Gene3D G3DSA:3.40.50.740 359 461 1.6E-38 T 06-07-2017 CAK77_RS15140 aec0a57fd910fa47e94d55b013380bb5 774 Gene3D G3DSA:3.40.228.10 155 358 3.4E-42 T 06-07-2017 CAK77_RS15140 aec0a57fd910fa47e94d55b013380bb5 774 SUPERFAMILY SSF50692 622 771 6.1E-42 T 06-07-2017 IPR009010 Aspartate decarboxylase-like domain CAK77_RS15140 aec0a57fd910fa47e94d55b013380bb5 774 Pfam PF00384 Molybdopterin oxidoreductase 62 515 3.4E-58 T 06-07-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS15140 aec0a57fd910fa47e94d55b013380bb5 774 Gene3D G3DSA:2.40.40.20 602 764 1.3E-52 T 06-07-2017 CAK77_RS15140 aec0a57fd910fa47e94d55b013380bb5 774 SUPERFAMILY SSF53706 20 630 3.8E-152 T 06-07-2017 CAK77_RS15140 aec0a57fd910fa47e94d55b013380bb5 774 Pfam PF01568 Molydopterin dinucleotide binding domain 628 745 4.6E-23 T 06-07-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CAK77_RS15140 aec0a57fd910fa47e94d55b013380bb5 774 Gene3D G3DSA:3.90.55.10 462 561 9.0E-29 T 06-07-2017 CAK77_RS12165 e0ba11a88166ecc0383840ab272fefd4 338 Pfam PF01028 Eukaryotic DNA topoisomerase I, catalytic core 83 287 4.3E-23 T 06-07-2017 IPR013500 DNA topoisomerase I, catalytic core, eukaryotic-type GO:0003677|GO:0003918|GO:0006265 CAK77_RS12165 e0ba11a88166ecc0383840ab272fefd4 338 SUPERFAMILY SSF56349 78 311 1.91E-56 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CAK77_RS12165 e0ba11a88166ecc0383840ab272fefd4 338 SUPERFAMILY SSF55869 22 82 2.62E-20 T 06-07-2017 CAK77_RS12165 e0ba11a88166ecc0383840ab272fefd4 338 Gene3D G3DSA:3.90.15.10 88 215 4.5E-27 T 06-07-2017 IPR014711 DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type GO:0003677|GO:0003917|GO:0006265 CAK77_RS12165 e0ba11a88166ecc0383840ab272fefd4 338 Gene3D G3DSA:1.20.120.380 233 315 9.4E-21 T 06-07-2017 IPR027362 DNA topoisomerase I catalytic fragment, domain 2 CAK77_RS12165 e0ba11a88166ecc0383840ab272fefd4 338 PRINTS PR00416 Eukaryotic DNA topoisomerase I signature 145 159 3.3E-7 T 06-07-2017 IPR001631 DNA topoisomerase I GO:0003677|GO:0003917|GO:0006265 CAK77_RS12165 e0ba11a88166ecc0383840ab272fefd4 338 PRINTS PR00416 Eukaryotic DNA topoisomerase I signature 166 182 3.3E-7 T 06-07-2017 IPR001631 DNA topoisomerase I GO:0003677|GO:0003917|GO:0006265 CAK77_RS12165 e0ba11a88166ecc0383840ab272fefd4 338 PRINTS PR00416 Eukaryotic DNA topoisomerase I signature 122 141 3.3E-7 T 06-07-2017 IPR001631 DNA topoisomerase I GO:0003677|GO:0003917|GO:0006265 CAK77_RS12165 e0ba11a88166ecc0383840ab272fefd4 338 PRINTS PR00416 Eukaryotic DNA topoisomerase I signature 232 246 3.3E-7 T 06-07-2017 IPR001631 DNA topoisomerase I GO:0003677|GO:0003917|GO:0006265 CAK77_RS12165 e0ba11a88166ecc0383840ab272fefd4 338 PRINTS PR00416 Eukaryotic DNA topoisomerase I signature 284 295 3.3E-7 T 06-07-2017 IPR001631 DNA topoisomerase I GO:0003677|GO:0003917|GO:0006265 CAK77_RS09915 7de44b6521c722c4b40fc250852744d4 499 SUPERFAMILY SSF53901 282 392 2.81E-14 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS09915 7de44b6521c722c4b40fc250852744d4 499 SUPERFAMILY SSF53901 231 256 9.91E-11 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS09915 7de44b6521c722c4b40fc250852744d4 499 SUPERFAMILY SSF53901 20 123 9.91E-11 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS09915 7de44b6521c722c4b40fc250852744d4 499 Gene3D G3DSA:3.40.47.10 223 254 8.1E-8 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS09915 7de44b6521c722c4b40fc250852744d4 499 Gene3D G3DSA:3.40.47.10 27 117 8.1E-8 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS09915 7de44b6521c722c4b40fc250852744d4 499 Gene3D G3DSA:3.40.47.10 292 346 7.4E-4 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS00575 2d97fe78ca1c4e87d86ef0096150682f 312 Gene3D G3DSA:2.60.40.1610 37 72 8.6E-5 T 06-07-2017 IPR010679 Domain of unknown function DUF1254 CAK77_RS00575 2d97fe78ca1c4e87d86ef0096150682f 312 Gene3D G3DSA:2.60.120.600 169 311 1.8E-31 T 06-07-2017 IPR010621 Domain of unknown function DUF1214 CAK77_RS00575 2d97fe78ca1c4e87d86ef0096150682f 312 Pfam PF06742 Protein of unknown function (DUF1214) 202 295 2.7E-14 T 06-07-2017 IPR010621 Domain of unknown function DUF1214 CAK77_RS00575 2d97fe78ca1c4e87d86ef0096150682f 312 SUPERFAMILY SSF160935 9 311 2.09E-72 T 06-07-2017 CAK77_RS00575 2d97fe78ca1c4e87d86ef0096150682f 312 Pfam PF06863 Protein of unknown function (DUF1254) 25 79 1.8E-12 T 06-07-2017 IPR010679 Domain of unknown function DUF1254 CAK77_RS16740 71a3cf1cc90af4ffca290fc1fb0cf7ac 414 SUPERFAMILY SSF53756 1 390 4.0E-96 T 06-07-2017 CAK77_RS16740 71a3cf1cc90af4ffca290fc1fb0cf7ac 414 Pfam PF00534 Glycosyl transferases group 1 210 369 1.6E-41 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 CAK77_RS16740 71a3cf1cc90af4ffca290fc1fb0cf7ac 414 Gene3D G3DSA:3.40.50.2000 183 371 5.8E-42 T 06-07-2017 CAK77_RS16740 71a3cf1cc90af4ffca290fc1fb0cf7ac 414 Pfam PF13439 Glycosyltransferase Family 4 15 203 2.8E-29 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 CAK77_RS10870 bd434adc79190de9e0805aad7b9be039 523 Pfam PF00823 PPE family 8 164 6.0E-57 T 06-07-2017 IPR000030 PPE family CAK77_RS10870 bd434adc79190de9e0805aad7b9be039 523 SUPERFAMILY SSF140459 5 177 6.28E-60 T 06-07-2017 CAK77_RS24420 55e16b62a116a75887e241471dc4e531 343 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 20 205 3.2E-40 T 06-07-2017 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal CAK77_RS24420 55e16b62a116a75887e241471dc4e531 343 SMART SM00342 246 328 5.4E-25 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK77_RS24420 55e16b62a116a75887e241471dc4e531 343 Gene3D G3DSA:1.10.10.60 281 332 4.3E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS24420 55e16b62a116a75887e241471dc4e531 343 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 312 328 9.4E-5 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CAK77_RS24420 55e16b62a116a75887e241471dc4e531 343 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 297 312 9.4E-5 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CAK77_RS24420 55e16b62a116a75887e241471dc4e531 343 SUPERFAMILY SSF46689 282 332 7.62E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS24420 55e16b62a116a75887e241471dc4e531 343 Pfam PF12833 Helix-turn-helix domain 253 330 7.1E-19 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK77_RS17355 55e16b62a116a75887e241471dc4e531 343 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 20 205 3.2E-40 T 06-07-2017 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal CAK77_RS17355 55e16b62a116a75887e241471dc4e531 343 SMART SM00342 246 328 5.4E-25 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK77_RS17355 55e16b62a116a75887e241471dc4e531 343 Gene3D G3DSA:1.10.10.60 281 332 4.3E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS17355 55e16b62a116a75887e241471dc4e531 343 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 312 328 9.4E-5 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CAK77_RS17355 55e16b62a116a75887e241471dc4e531 343 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 297 312 9.4E-5 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CAK77_RS17355 55e16b62a116a75887e241471dc4e531 343 SUPERFAMILY SSF46689 282 332 7.62E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS17355 55e16b62a116a75887e241471dc4e531 343 Pfam PF12833 Helix-turn-helix domain 253 330 7.1E-19 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK77_RS14810 a51425b267d5569c0c3a7196afa99568 454 Pfam PF09594 Protein of unknown function (DUF2029) 85 322 2.5E-37 T 06-07-2017 IPR018584 Glycosyltransferase family 87 GO:0016758 CAK77_RS11430 00c7d7f691a27af46c2ac3f2f49b31f4 989 SUPERFAMILY SSF53474 54 357 5.87E-29 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS11430 00c7d7f691a27af46c2ac3f2f49b31f4 989 SUPERFAMILY SSF56801 441 955 1.7E-50 T 06-07-2017 CAK77_RS11430 00c7d7f691a27af46c2ac3f2f49b31f4 989 Gene3D G3DSA:3.40.50.980 610 762 7.4E-14 T 06-07-2017 CAK77_RS11430 00c7d7f691a27af46c2ac3f2f49b31f4 989 Gene3D G3DSA:3.40.50.980 449 609 7.7E-16 T 06-07-2017 CAK77_RS11430 00c7d7f691a27af46c2ac3f2f49b31f4 989 Pfam PF00501 AMP-binding enzyme 453 854 2.3E-31 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK77_RS11430 00c7d7f691a27af46c2ac3f2f49b31f4 989 Pfam PF12697 Alpha/beta hydrolase family 89 341 3.4E-6 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS11430 00c7d7f691a27af46c2ac3f2f49b31f4 989 Gene3D G3DSA:3.40.50.1820 63 357 9.7E-27 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS17315 6aff9c72611688a3d357c5659e74e0a7 227 Pfam PF14032 PknH-like extracellular domain 50 225 5.7E-22 T 06-07-2017 IPR026954 PknH-like extracellular domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 CAK77_RS11625 7fb0c18cd238df30455f8fc2ac898c4c 158 Gene3D G3DSA:3.30.530.20 2 154 9.2E-10 T 06-07-2017 IPR023393 START-like domain CAK77_RS11625 7fb0c18cd238df30455f8fc2ac898c4c 158 SUPERFAMILY SSF55961 2 154 2.16E-14 T 06-07-2017 CAK77_RS11625 7fb0c18cd238df30455f8fc2ac898c4c 158 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 3 153 1.1E-10 T 06-07-2017 IPR019587 Polyketide cyclase/dehydrase CAK77_RS21750 81e2950573b85d6629cdd3b6f865ce2c 447 Gene3D G3DSA:3.40.309.10 247 420 2.4E-49 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAK77_RS21750 81e2950573b85d6629cdd3b6f865ce2c 447 Pfam PF00171 Aldehyde dehydrogenase family 3 442 3.8E-123 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAK77_RS21750 81e2950573b85d6629cdd3b6f865ce2c 447 Gene3D G3DSA:3.40.605.10 4 246 2.8E-67 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAK77_RS21750 81e2950573b85d6629cdd3b6f865ce2c 447 SUPERFAMILY SSF53720 4 444 7.33E-127 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAK77_RS21750 81e2950573b85d6629cdd3b6f865ce2c 447 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 259 270 - T 06-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CAK77_RS06025 d80e7f8fcaa55601a861df8398f9790a 302 SUPERFAMILY SSF52980 169 282 2.73E-5 T 06-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CAK77_RS06025 d80e7f8fcaa55601a861df8398f9790a 302 Pfam PF04480 Protein of unknown function (DUF559) 217 281 5.4E-6 T 06-07-2017 IPR007569 Domain of unknown function DUF559 CAK77_RS11050 b1cf4bcf73c7cf32a1a613036cb539fe 421 Pfam PF07690 Major Facilitator Superfamily 30 367 7.9E-19 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK77_RS11050 b1cf4bcf73c7cf32a1a613036cb539fe 421 Gene3D G3DSA:1.20.1250.20 220 403 8.9E-14 T 06-07-2017 CAK77_RS11050 b1cf4bcf73c7cf32a1a613036cb539fe 421 Gene3D G3DSA:1.20.1250.20 21 201 2.8E-14 T 06-07-2017 CAK77_RS11050 b1cf4bcf73c7cf32a1a613036cb539fe 421 SUPERFAMILY SSF103473 12 403 2.35E-42 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK77_RS23770 cb110d5e371e22101ba190879c862d00 333 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 167 326 5.6E-17 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CAK77_RS23770 cb110d5e371e22101ba190879c862d00 333 SUPERFAMILY SSF55073 162 322 3.77E-37 T 06-07-2017 IPR029787 Nucleotide cyclase CAK77_RS23770 cb110d5e371e22101ba190879c862d00 333 Gene3D G3DSA:3.30.70.1230 167 322 1.6E-24 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CAK77_RS23770 cb110d5e371e22101ba190879c862d00 333 SMART SM00044 129 311 3.2E-4 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CAK77_RS17935 3c133e60badb73f6140123bc64a2f94e 166 SUPERFAMILY SSF55486 37 159 2.31E-22 T 06-07-2017 CAK77_RS17935 3c133e60badb73f6140123bc64a2f94e 166 Pfam PF06262 Zinicin-like metallopeptidase 64 157 4.2E-6 T 06-07-2017 IPR010428 Zinicin-like metallopeptidase CAK77_RS23080 44dbb1d735f23693675a8c57c16c242f 354 TIGRFAM TIGR00209 galT_1: galactose-1-phosphate uridylyltransferase 37 353 1.7E-41 T 06-07-2017 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0006012|GO:0008108|GO:0008270 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 CAK77_RS23080 44dbb1d735f23693675a8c57c16c242f 354 Gene3D G3DSA:3.30.428.10 191 353 2.3E-47 T 06-07-2017 IPR011146 HIT-like domain GO:0003824 CAK77_RS23080 44dbb1d735f23693675a8c57c16c242f 354 SUPERFAMILY SSF54197 193 353 4.35E-37 T 06-07-2017 IPR011146 HIT-like domain GO:0003824 CAK77_RS23080 44dbb1d735f23693675a8c57c16c242f 354 Pfam PF01087 Galactose-1-phosphate uridyl transferase, N-terminal domain 37 188 3.5E-36 T 06-07-2017 IPR005849 Galactose-1-phosphate uridyl transferase, N-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 CAK77_RS23080 44dbb1d735f23693675a8c57c16c242f 354 Gene3D G3DSA:3.30.428.10 63 188 2.3E-36 T 06-07-2017 IPR011146 HIT-like domain GO:0003824 CAK77_RS23080 44dbb1d735f23693675a8c57c16c242f 354 Pfam PF02744 Galactose-1-phosphate uridyl transferase, C-terminal domain 202 351 2.4E-15 T 06-07-2017 IPR005850 Galactose-1-phosphate uridyl transferase, C-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 CAK77_RS23080 44dbb1d735f23693675a8c57c16c242f 354 SUPERFAMILY SSF54197 36 188 7.56E-48 T 06-07-2017 IPR011146 HIT-like domain GO:0003824 CAK77_RS23080 44dbb1d735f23693675a8c57c16c242f 354 PIRSF PIRSF000808 34 354 1.4E-101 T 06-07-2017 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0006012|GO:0008108|GO:0008270 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 CAK77_RS03305 0bdcd65b7485ebcd0f4ecd65c6db8c01 237 Hamap MF_00664 Phosphatidylserine decarboxylase proenzyme [psd]. 29 237 33.114 T 06-07-2017 IPR033175 Phosphatidylserine decarboxylase, archaeal-type KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 CAK77_RS03305 0bdcd65b7485ebcd0f4ecd65c6db8c01 237 TIGRFAM TIGR00164 PS_decarb_rel: phosphatidylserine decarboxylase homolog 34 235 2.6E-45 T 06-07-2017 IPR033175 Phosphatidylserine decarboxylase, archaeal-type KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 CAK77_RS03305 0bdcd65b7485ebcd0f4ecd65c6db8c01 237 Pfam PF02666 Phosphatidylserine decarboxylase 68 233 6.2E-27 T 06-07-2017 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 CAK77_RS08910 00d8f7cdb492bdde256f22ab13619f3f 208 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 15 139 6.2E-13 T 06-07-2017 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 CAK77_RS08910 00d8f7cdb492bdde256f22ab13619f3f 208 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 14 178 7.7E-21 T 06-07-2017 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type CAK77_RS08910 00d8f7cdb492bdde256f22ab13619f3f 208 SUPERFAMILY SSF109854 1 143 2.59E-15 T 06-07-2017 CAK77_RS08910 00d8f7cdb492bdde256f22ab13619f3f 208 TIGRFAM TIGR03086 TIGR03086: TIGR03086 family protein 11 198 5.2E-36 T 06-07-2017 IPR017520 Conserved hypothetical protein CHP03086 CAK77_RS18985 56b27313a9eb2675c2a760b7c44ca596 61 SUPERFAMILY SSF57716 5 61 5.56E-21 T 06-07-2017 CAK77_RS18985 56b27313a9eb2675c2a760b7c44ca596 61 Pfam PF00253 Ribosomal protein S14p/S29e 9 60 8.2E-25 T 06-07-2017 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS18985 56b27313a9eb2675c2a760b7c44ca596 61 ProSitePatterns PS00527 Ribosomal protein S14 signature. 23 45 - T 06-07-2017 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAK77_RS18985 56b27313a9eb2675c2a760b7c44ca596 61 Hamap MF_01364_B 30S ribosomal protein S14 type Z [rpsZ]. 1 61 25.327 T 06-07-2017 IPR023053 Ribosomal protein S14, type Z CAK77_RS18985 56b27313a9eb2675c2a760b7c44ca596 61 Gene3D G3DSA:4.10.830.10 1 61 1.4E-27 T 06-07-2017 CAK77_RS22450 1cf218b71f485e8609fd09d6dfdd66b5 218 Pfam PF13305 WHG domain 100 181 2.0E-14 T 06-07-2017 IPR025996 WHG domain CAK77_RS22450 1cf218b71f485e8609fd09d6dfdd66b5 218 SUPERFAMILY SSF48498 93 202 4.54E-15 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS22450 1cf218b71f485e8609fd09d6dfdd66b5 218 Gene3D G3DSA:1.10.357.10 74 197 6.6E-18 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS22450 1cf218b71f485e8609fd09d6dfdd66b5 218 Gene3D G3DSA:1.10.10.60 21 73 1.2E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS22450 1cf218b71f485e8609fd09d6dfdd66b5 218 SUPERFAMILY SSF46689 15 98 5.64E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS22450 1cf218b71f485e8609fd09d6dfdd66b5 218 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 72 4.2E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS22465 8ed289e6c43897331e3b54d8675951a1 375 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 12 300 4.2E-45 T 06-07-2017 IPR005693 Virulence factor Mce protein CAK77_RS22465 8ed289e6c43897331e3b54d8675951a1 375 Pfam PF02470 MlaD protein 38 113 1.1E-11 T 06-07-2017 IPR003399 Mce/MlaD CAK77_RS08370 177f70fbd2c693c8cc2615f0749a56b4 332 SUPERFAMILY SSF51412 7 330 4.12E-52 T 06-07-2017 CAK77_RS08370 177f70fbd2c693c8cc2615f0749a56b4 332 Pfam PF03060 Nitronate monooxygenase 11 324 9.9E-76 T 06-07-2017 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 CAK77_RS08370 177f70fbd2c693c8cc2615f0749a56b4 332 Gene3D G3DSA:3.20.20.70 7 319 2.5E-54 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK77_RS04985 24af6b4ad172b54810f1f6ec50f9ef24 391 Pfam PF02720 Domain of unknown function (DUF222) 29 354 4.6E-89 T 06-07-2017 IPR003870 Domain of unknown function DUF222 CAK77_RS04985 24af6b4ad172b54810f1f6ec50f9ef24 391 ProDom PD008243 RV1792C/MT1741/MB1728C RV1945/MT1995 MB1980 MB0098C RV3466/MT3572 VERY RV1128C/MT1160 RV1148C/MT1183 MB1159C RV0095C 7 89 7.0E-6 T 06-07-2017 CAK77_RS20030 ed6b4d3dab35e6d8a7c461b9609404d6 114 TIGRFAM TIGR04529 MTB_hemophore: hemophore-related protein, Rv0203/Rv1174c family 33 108 7.9E-27 T 06-07-2017 IPR032407 Haemophore, haem-binding GO:0020037 CAK77_RS20030 ed6b4d3dab35e6d8a7c461b9609404d6 114 Pfam PF16525 Haemophore, haem-binding 32 107 3.9E-33 T 06-07-2017 IPR032407 Haemophore, haem-binding GO:0020037 CAK77_RS23955 0b475a901a273b1edbde0406de5f823b 270 Pfam PF03988 Repeat of Unknown Function (DUF347) 69 127 1.5E-12 T 06-07-2017 IPR007136 Protein of unknown function DUF347 CAK77_RS23955 0b475a901a273b1edbde0406de5f823b 270 Pfam PF03988 Repeat of Unknown Function (DUF347) 14 65 1.6E-16 T 06-07-2017 IPR007136 Protein of unknown function DUF347 CAK77_RS23955 0b475a901a273b1edbde0406de5f823b 270 Pfam PF03988 Repeat of Unknown Function (DUF347) 142 191 8.7E-15 T 06-07-2017 IPR007136 Protein of unknown function DUF347 CAK77_RS23955 0b475a901a273b1edbde0406de5f823b 270 Pfam PF03988 Repeat of Unknown Function (DUF347) 197 250 3.4E-12 T 06-07-2017 IPR007136 Protein of unknown function DUF347 CAK77_RS23925 47cf9e669b2c686b7ad5b3bc39e50079 398 Gene3D G3DSA:3.10.350.10 3 51 4.9E-7 T 06-07-2017 IPR018392 LysM domain CAK77_RS23925 47cf9e669b2c686b7ad5b3bc39e50079 398 Gene3D G3DSA:3.10.350.10 54 101 4.1E-6 T 06-07-2017 IPR018392 LysM domain CAK77_RS23925 47cf9e669b2c686b7ad5b3bc39e50079 398 Gene3D G3DSA:3.40.50.1820 121 372 8.3E-51 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS23925 47cf9e669b2c686b7ad5b3bc39e50079 398 SUPERFAMILY SSF53474 120 372 5.27E-38 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS23925 47cf9e669b2c686b7ad5b3bc39e50079 398 Pfam PF01476 LysM domain 56 101 5.0E-5 T 06-07-2017 IPR018392 LysM domain CAK77_RS23925 47cf9e669b2c686b7ad5b3bc39e50079 398 Pfam PF01476 LysM domain 5 51 1.5E-6 T 06-07-2017 IPR018392 LysM domain CAK77_RS23925 47cf9e669b2c686b7ad5b3bc39e50079 398 SMART SM00257 4 51 6.1E-8 T 06-07-2017 IPR018392 LysM domain CAK77_RS23925 47cf9e669b2c686b7ad5b3bc39e50079 398 SMART SM00257 55 102 3.6E-7 T 06-07-2017 IPR018392 LysM domain CAK77_RS23925 47cf9e669b2c686b7ad5b3bc39e50079 398 Pfam PF00756 Putative esterase 131 384 1.2E-55 T 06-07-2017 IPR000801 Putative esterase Reactome: R-HSA-156590 CAK77_RS13540 75c886743951a2293ca49173fdad9a13 247 Gene3D G3DSA:3.40.50.1360 18 247 2.1E-73 T 06-07-2017 CAK77_RS13540 75c886743951a2293ca49173fdad9a13 247 SUPERFAMILY SSF100950 8 246 1.85E-67 T 06-07-2017 CAK77_RS13540 75c886743951a2293ca49173fdad9a13 247 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 11 236 3.2E-73 T 06-07-2017 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 CAK77_RS13540 75c886743951a2293ca49173fdad9a13 247 TIGRFAM TIGR01198 pgl: 6-phosphogluconolactonase 11 246 4.2E-74 T 06-07-2017 IPR005900 6-phosphogluconolactonase, DevB-type GO:0005975|GO:0006098|GO:0017057 KEGG: 00030+3.1.1.31 CAK77_RS01535 176643f346ff85909987b46f217baf12 325 SUPERFAMILY SSF51556 5 316 2.13E-72 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK77_RS01535 176643f346ff85909987b46f217baf12 325 Gene3D G3DSA:3.20.20.140 5 316 5.5E-84 T 06-07-2017 CAK77_RS01535 176643f346ff85909987b46f217baf12 325 Pfam PF04909 Amidohydrolase 6 316 5.1E-45 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAK77_RS18180 ba0288aece887d92eb49d03aa3cbb6d6 226 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 41 1.8E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS18180 ba0288aece887d92eb49d03aa3cbb6d6 226 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 49 72 1.8E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS18180 ba0288aece887d92eb49d03aa3cbb6d6 226 SUPERFAMILY SSF46689 16 86 1.35E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS18180 ba0288aece887d92eb49d03aa3cbb6d6 226 Pfam PF00440 Bacterial regulatory proteins, tetR family 28 73 6.9E-13 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS18180 ba0288aece887d92eb49d03aa3cbb6d6 226 Gene3D G3DSA:1.10.357.10 11 207 5.4E-32 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS17890 8938deaf4e11ab47638d9fcd199826a8 67 Pfam PF00301 Rubredoxin 14 59 6.7E-22 T 06-07-2017 IPR024935 Rubredoxin domain GO:0005506 CAK77_RS17890 8938deaf4e11ab47638d9fcd199826a8 67 SUPERFAMILY SSF57802 10 64 4.38E-22 T 06-07-2017 CAK77_RS17890 8938deaf4e11ab47638d9fcd199826a8 67 ProSitePatterns PS00202 Rubredoxin signature. 43 53 - T 06-07-2017 IPR018527 Rubredoxin, iron-binding site GO:0046872 CAK77_RS17890 8938deaf4e11ab47638d9fcd199826a8 67 PRINTS PR00163 Rubredoxin signature 13 29 5.7E-8 T 06-07-2017 IPR024935 Rubredoxin domain GO:0005506 CAK77_RS17890 8938deaf4e11ab47638d9fcd199826a8 67 PRINTS PR00163 Rubredoxin signature 43 59 5.7E-8 T 06-07-2017 IPR024935 Rubredoxin domain GO:0005506 CAK77_RS17890 8938deaf4e11ab47638d9fcd199826a8 67 Gene3D G3DSA:2.20.28.10 10 64 6.9E-25 T 06-07-2017 IPR004039 Rubredoxin-type fold CAK77_RS13365 8975bf7e6cfe89210814325a0ad46035 476 Pfam PF00877 NlpC/P60 family 359 473 1.9E-28 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain CAK77_RS13365 8975bf7e6cfe89210814325a0ad46035 476 SUPERFAMILY SSF54001 343 462 7.36E-31 T 06-07-2017 CAK77_RS13365 8975bf7e6cfe89210814325a0ad46035 476 Gene3D G3DSA:3.90.1720.10 341 473 3.6E-37 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain CAK77_RS23850 9a243bf4802177ab374ed8453e3af01c 242 SUPERFAMILY SSF48498 99 234 1.26E-18 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS23850 9a243bf4802177ab374ed8453e3af01c 242 Pfam PF00440 Bacterial regulatory proteins, tetR family 29 71 1.2E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS23850 9a243bf4802177ab374ed8453e3af01c 242 SUPERFAMILY SSF46689 14 85 1.32E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS23850 9a243bf4802177ab374ed8453e3af01c 242 Gene3D G3DSA:1.10.357.10 12 237 9.1E-37 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS02065 4a0267d9b393b1c7585a398d4648ddbb 83 Gene3D G3DSA:3.40.30.10 8 80 5.0E-25 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK77_RS02065 4a0267d9b393b1c7585a398d4648ddbb 83 Pfam PF00462 Glutaredoxin 9 67 4.3E-16 T 06-07-2017 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 CAK77_RS02065 4a0267d9b393b1c7585a398d4648ddbb 83 SUPERFAMILY SSF52833 8 78 1.49E-18 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK77_RS04200 f20169937fe787a85ab264a554de454a 506 Pfam PF13556 PucR C-terminal helix-turn-helix domain 443 501 7.8E-18 T 06-07-2017 IPR025736 PucR C-terminal helix-turn-helix domain CAK77_RS04200 f20169937fe787a85ab264a554de454a 506 Pfam PF07905 Purine catabolism regulatory protein-like family 15 132 4.0E-27 T 06-07-2017 IPR012914 Purine catabolism PurC-like domain CAK77_RS03225 6a04fd1dfc9fb2314bd2e3ae0d65a45d 533 SUPERFAMILY SSF56425 313 455 2.06E-20 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK77_RS03225 6a04fd1dfc9fb2314bd2e3ae0d65a45d 533 Gene3D G3DSA:3.90.700.10 322 454 9.9E-19 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK77_RS03225 6a04fd1dfc9fb2314bd2e3ae0d65a45d 533 Gene3D G3DSA:3.50.50.60 245 309 1.3E-67 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS03225 6a04fd1dfc9fb2314bd2e3ae0d65a45d 533 Gene3D G3DSA:3.50.50.60 9 202 1.3E-67 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS03225 6a04fd1dfc9fb2314bd2e3ae0d65a45d 533 Gene3D G3DSA:3.50.50.60 468 526 1.3E-67 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS03225 6a04fd1dfc9fb2314bd2e3ae0d65a45d 533 Pfam PF00890 FAD binding domain 11 502 9.6E-47 T 06-07-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK77_RS03225 6a04fd1dfc9fb2314bd2e3ae0d65a45d 533 SUPERFAMILY SSF51905 466 526 2.2E-35 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS03225 6a04fd1dfc9fb2314bd2e3ae0d65a45d 533 SUPERFAMILY SSF51905 244 306 2.2E-35 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS03225 6a04fd1dfc9fb2314bd2e3ae0d65a45d 533 SUPERFAMILY SSF51905 7 202 2.2E-35 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS06840 2b8715fe977d26feb88903646eb1f2f6 378 ProSitePatterns PS01215 Mrp family signature. 217 233 - T 06-07-2017 IPR000808 Mrp, conserved site GO:0005524 CAK77_RS06840 2b8715fe977d26feb88903646eb1f2f6 378 Gene3D G3DSA:3.40.50.300 106 357 6.6E-85 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS06840 2b8715fe977d26feb88903646eb1f2f6 378 Hamap MF_02040 Iron-sulfur cluster carrier protein. 104 359 33.488 T 06-07-2017 IPR019591 Mrp/NBP35 ATP-binding protein CAK77_RS06840 2b8715fe977d26feb88903646eb1f2f6 378 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 113 358 1.7E-88 T 06-07-2017 IPR019591 Mrp/NBP35 ATP-binding protein CAK77_RS06840 2b8715fe977d26feb88903646eb1f2f6 378 SUPERFAMILY SSF52540 113 361 9.31E-51 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS06840 2b8715fe977d26feb88903646eb1f2f6 378 SUPERFAMILY SSF117916 6 96 2.42E-20 T 06-07-2017 CAK77_RS06840 2b8715fe977d26feb88903646eb1f2f6 378 Pfam PF01883 Domain of unknown function DUF59 7 78 1.3E-16 T 06-07-2017 IPR002744 Domain of unknown function DUF59 CAK77_RS19325 a4e9b9abce2d26c843fcf18acd942966 459 Gene3D G3DSA:1.20.1250.20 40 177 2.7E-9 T 06-07-2017 CAK77_RS19325 a4e9b9abce2d26c843fcf18acd942966 459 SUPERFAMILY SSF103473 237 440 1.31E-12 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK77_RS19325 a4e9b9abce2d26c843fcf18acd942966 459 SUPERFAMILY SSF103473 40 191 1.31E-12 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK77_RS16770 910e21a7c3a02f4a81b7b5a6b170ebe7 215 ProSitePatterns PS01081 TetR-type HTH domain signature. 48 79 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CAK77_RS16770 910e21a7c3a02f4a81b7b5a6b170ebe7 215 SUPERFAMILY SSF46689 22 101 5.49E-20 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS16770 910e21a7c3a02f4a81b7b5a6b170ebe7 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 57 80 1.1E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS16770 910e21a7c3a02f4a81b7b5a6b170ebe7 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 49 1.1E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS16770 910e21a7c3a02f4a81b7b5a6b170ebe7 215 Pfam PF00440 Bacterial regulatory proteins, tetR family 36 82 3.4E-16 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS16770 910e21a7c3a02f4a81b7b5a6b170ebe7 215 Gene3D G3DSA:1.10.357.10 20 213 5.6E-39 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS16770 910e21a7c3a02f4a81b7b5a6b170ebe7 215 SUPERFAMILY SSF48498 108 213 9.18E-9 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS05345 83ddca34a3be225aad58f4ed2b0ca40d 212 SUPERFAMILY SSF53328 17 210 2.49E-55 T 06-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CAK77_RS05345 83ddca34a3be225aad58f4ed2b0ca40d 212 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 17 200 27.527 T 06-07-2017 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 CAK77_RS05345 83ddca34a3be225aad58f4ed2b0ca40d 212 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 146 169 - T 06-07-2017 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CAK77_RS05345 83ddca34a3be225aad58f4ed2b0ca40d 212 Gene3D G3DSA:3.40.50.170 16 208 4.4E-63 T 06-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CAK77_RS05345 83ddca34a3be225aad58f4ed2b0ca40d 212 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 16 201 2.7E-66 T 06-07-2017 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 CAK77_RS05345 83ddca34a3be225aad58f4ed2b0ca40d 212 Pfam PF00551 Formyl transferase 17 194 2.6E-45 T 06-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CAK77_RS23985 b2e34c84731f88972e8e15e7877d46d7 67 SUPERFAMILY SSF51735 30 59 9.09E-7 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS23985 b2e34c84731f88972e8e15e7877d46d7 67 Gene3D G3DSA:3.40.50.720 32 58 1.6E-6 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS10485 86832527e6ea75c55a3d8e8f99c3c91d 269 Pfam PF13622 Thioesterase-like superfamily 29 266 3.3E-33 T 06-07-2017 CAK77_RS10485 86832527e6ea75c55a3d8e8f99c3c91d 269 SUPERFAMILY SSF54637 156 266 6.72E-12 T 06-07-2017 IPR029069 HotDog domain CAK77_RS17550 96af7a913e09c0fe063d69b03226fd78 292 Gene3D G3DSA:3.40.50.720 141 285 2.0E-4 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS17550 96af7a913e09c0fe063d69b03226fd78 292 Pfam PF00899 ThiF family 135 267 1.2E-5 T 06-07-2017 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CAK77_RS10380 a91c7c141f7e4b3cd60eb452b032e67a 184 SUPERFAMILY SSF56770 9 152 4.58E-64 T 06-07-2017 CAK77_RS10380 a91c7c141f7e4b3cd60eb452b032e67a 184 ProSitePatterns PS01150 Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. 118 134 - T 06-07-2017 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS10380 a91c7c141f7e4b3cd60eb452b032e67a 184 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 1 151 42.248 T 06-07-2017 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS10380 a91c7c141f7e4b3cd60eb452b032e67a 184 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 37 146 1.5E-24 T 06-07-2017 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS10380 a91c7c141f7e4b3cd60eb452b032e67a 184 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 11 151 1.4E-67 T 06-07-2017 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS10380 a91c7c141f7e4b3cd60eb452b032e67a 184 Gene3D G3DSA:3.40.50.700 27 149 1.9E-34 T 06-07-2017 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS04855 ee84c5564471b745cfb8c4559b0a6872 956 Pfam PF03176 MMPL family 601 935 2.4E-95 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 CAK77_RS04855 ee84c5564471b745cfb8c4559b0a6872 956 Pfam PF03176 MMPL family 51 379 1.1E-109 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 CAK77_RS04855 ee84c5564471b745cfb8c4559b0a6872 956 TIGRFAM TIGR00833 actII: transport protein 17 926 2.0E-288 T 06-07-2017 IPR004707 Membrane transport protein MmpL family GO:0016021 CAK77_RS04855 ee84c5564471b745cfb8c4559b0a6872 956 SUPERFAMILY SSF82866 150 349 2.49E-27 T 06-07-2017 CAK77_RS04855 ee84c5564471b745cfb8c4559b0a6872 956 SUPERFAMILY SSF82866 698 926 1.31E-32 T 06-07-2017 CAK77_RS04855 ee84c5564471b745cfb8c4559b0a6872 956 Gene3D G3DSA:1.20.1640.10 149 355 2.6E-28 T 06-07-2017 CAK77_RS04855 ee84c5564471b745cfb8c4559b0a6872 956 Gene3D G3DSA:1.20.1640.10 732 926 1.3E-22 T 06-07-2017 CAK77_RS03780 b141d7faa06f781931e1a0ac48276d1d 494 SUPERFAMILY SSF53720 10 486 2.49E-176 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAK77_RS03780 b141d7faa06f781931e1a0ac48276d1d 494 Pfam PF00171 Aldehyde dehydrogenase family 20 482 7.0E-181 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAK77_RS03780 b141d7faa06f781931e1a0ac48276d1d 494 Gene3D G3DSA:3.40.309.10 268 457 2.7E-74 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAK77_RS03780 b141d7faa06f781931e1a0ac48276d1d 494 Gene3D G3DSA:3.40.605.10 12 267 4.3E-101 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAK77_RS03780 b141d7faa06f781931e1a0ac48276d1d 494 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 254 261 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CAK77_RS19180 02079b973a8e1f675e17d0a569447304 293 SUPERFAMILY SSF52402 1 144 2.51E-19 T 06-07-2017 CAK77_RS19180 02079b973a8e1f675e17d0a569447304 293 PRINTS PR01438 Universal stress protein signature 270 292 3.4E-5 T 06-07-2017 IPR006015 Universal stress protein A CAK77_RS19180 02079b973a8e1f675e17d0a569447304 293 PRINTS PR01438 Universal stress protein signature 252 264 3.4E-5 T 06-07-2017 IPR006015 Universal stress protein A CAK77_RS19180 02079b973a8e1f675e17d0a569447304 293 Gene3D G3DSA:3.40.50.620 154 291 1.2E-21 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS19180 02079b973a8e1f675e17d0a569447304 293 Gene3D G3DSA:3.40.50.620 4 141 1.6E-18 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS19180 02079b973a8e1f675e17d0a569447304 293 SUPERFAMILY SSF52402 154 292 1.34E-22 T 06-07-2017 CAK77_RS19180 02079b973a8e1f675e17d0a569447304 293 Pfam PF00582 Universal stress protein family 2 139 2.9E-15 T 06-07-2017 IPR006016 UspA GO:0006950 CAK77_RS19180 02079b973a8e1f675e17d0a569447304 293 Pfam PF00582 Universal stress protein family 154 291 3.2E-18 T 06-07-2017 IPR006016 UspA GO:0006950 CAK77_RS05815 3dfb7cd407a56c7447587d07b9699471 159 Gene3D G3DSA:1.10.260.40 21 93 8.0E-6 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK77_RS00415 237996c010f6d3435f8cb29fe74ff179 111 Pfam PF16170 Domain of unknown function (DUF4873) 15 102 1.3E-29 T 06-07-2017 IPR032371 Domain of unknown function DUF4873 CAK77_RS15190 4cdd73d149c8d1f4e709c0a82ec707ff 339 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 51 287 1.3E-38 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAK77_RS15190 4cdd73d149c8d1f4e709c0a82ec707ff 339 Gene3D G3DSA:3.40.190.10 46 138 9.0E-18 T 06-07-2017 CAK77_RS15190 4cdd73d149c8d1f4e709c0a82ec707ff 339 Gene3D G3DSA:3.40.190.10 252 287 9.0E-18 T 06-07-2017 CAK77_RS15190 4cdd73d149c8d1f4e709c0a82ec707ff 339 SMART SM00062 48 297 3.5E-46 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAK77_RS15190 4cdd73d149c8d1f4e709c0a82ec707ff 339 SUPERFAMILY SSF53850 13 288 2.78E-44 T 06-07-2017 CAK77_RS15190 4cdd73d149c8d1f4e709c0a82ec707ff 339 Gene3D G3DSA:3.40.190.10 143 229 7.9E-18 T 06-07-2017 CAK77_RS07740 ed973463b6b8d137bf1ba429dc659c17 241 Gene3D G3DSA:1.10.357.10 7 199 1.2E-20 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS07740 ed973463b6b8d137bf1ba429dc659c17 241 SUPERFAMILY SSF48498 100 200 3.78E-5 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS07740 ed973463b6b8d137bf1ba429dc659c17 241 SUPERFAMILY SSF46689 9 89 1.13E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS07740 ed973463b6b8d137bf1ba429dc659c17 241 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 67 3.5E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS16275 90737ef7c3393f5d57688f887d671ec8 257 Gene3D G3DSA:3.40.30.10 196 248 5.1E-7 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK77_RS16275 90737ef7c3393f5d57688f887d671ec8 257 Pfam PF13462 Thioredoxin 78 246 4.0E-21 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK77_RS16275 90737ef7c3393f5d57688f887d671ec8 257 SUPERFAMILY SSF52833 77 246 5.96E-22 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK77_RS16275 90737ef7c3393f5d57688f887d671ec8 257 Gene3D G3DSA:3.40.30.10 78 171 4.0E-14 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK77_RS05010 cf3ca075b5ea744e87cfea1af1d89d6d 394 Pfam PF13515 Fusaric acid resistance protein-like 195 327 9.7E-25 T 06-07-2017 CAK77_RS05610 7f94aae7c29dc9381078bbd773be6fb8 494 Pfam PF00324 Amino acid permease 28 440 1.8E-105 T 06-07-2017 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CAK77_RS05610 7f94aae7c29dc9381078bbd773be6fb8 494 PIRSF PIRSF006060 2 474 5.9E-60 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CAK77_RS05610 7f94aae7c29dc9381078bbd773be6fb8 494 ProSitePatterns PS00218 Amino acid permeases signature. 52 82 - T 06-07-2017 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 CAK77_RS01870 bdb41e1251ef329eccf42321bf5261b1 226 Pfam PF13522 Glutamine amidotransferase domain 69 197 2.6E-16 T 06-07-2017 CAK77_RS01870 bdb41e1251ef329eccf42321bf5261b1 226 SUPERFAMILY SSF56235 2 223 1.72E-16 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAK77_RS01870 bdb41e1251ef329eccf42321bf5261b1 226 TIGRFAM TIGR03442 TIGR03442: ergothioneine biosynthesis protein EgtC 1 225 6.2E-85 T 06-07-2017 IPR017808 Ergothioneine biosynthesis protein EgtC GO:0052699 CAK77_RS01870 bdb41e1251ef329eccf42321bf5261b1 226 Gene3D G3DSA:3.60.20.10 1 224 1.7E-33 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAK77_RS01870 bdb41e1251ef329eccf42321bf5261b1 226 Hamap MF_02036 Gamma-glutamyl-hercynylcysteine sulfoxide hydrolase [egtC]. 1 226 36.112 T 06-07-2017 IPR032889 Gamma-glutamyl-hercynylcysteine sulfoxide hydrolase, Actinobacteria GO:0016811|GO:0052699 KEGG: 00311+3.5.1.11|KEGG: 00340+3.5.1.118|MetaCyc: PWY-7255 CAK77_RS04690 d863e96f03f1f2a72f9dd46ad6455016 119 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 29 116 1.5E-23 T 06-07-2017 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 CAK77_RS04690 d863e96f03f1f2a72f9dd46ad6455016 119 Gene3D G3DSA:3.10.50.40 13 117 7.3E-33 T 06-07-2017 CAK77_RS04690 d863e96f03f1f2a72f9dd46ad6455016 119 SUPERFAMILY SSF54534 14 117 8.64E-33 T 06-07-2017 CAK77_RS10830 a2de61386ba75cb075c76593bcb4b4ca 587 SUPERFAMILY SSF49785 340 566 9.14E-65 T 06-07-2017 IPR008979 Galactose-binding domain-like CAK77_RS10830 a2de61386ba75cb075c76593bcb4b4ca 587 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 7 282 8.7E-64 T 06-07-2017 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 CAK77_RS10830 a2de61386ba75cb075c76593bcb4b4ca 587 Gene3D G3DSA:1.10.3020.10 138 222 1.7E-15 T 06-07-2017 CAK77_RS10830 a2de61386ba75cb075c76593bcb4b4ca 587 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 4 566 2.5E-137 T 06-07-2017 IPR005674 CocE/Serine esterase GO:0016787 CAK77_RS10830 a2de61386ba75cb075c76593bcb4b4ca 587 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 327 560 1.3E-47 T 06-07-2017 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 CAK77_RS10830 a2de61386ba75cb075c76593bcb4b4ca 587 SMART SM00939 311 561 4.1E-76 T 06-07-2017 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 CAK77_RS10830 a2de61386ba75cb075c76593bcb4b4ca 587 Gene3D G3DSA:3.40.50.1820 1 137 6.6E-78 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS10830 a2de61386ba75cb075c76593bcb4b4ca 587 Gene3D G3DSA:3.40.50.1820 223 345 6.6E-78 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS10830 a2de61386ba75cb075c76593bcb4b4ca 587 SUPERFAMILY SSF53474 1 348 3.25E-60 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS10830 a2de61386ba75cb075c76593bcb4b4ca 587 Gene3D G3DSA:2.60.120.260 346 572 1.0E-77 T 06-07-2017 IPR008979 Galactose-binding domain-like CAK77_RS16950 69f9a184e7bdd6fdeda317cd788d475b 245 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 12 127 4.3E-18 T 06-07-2017 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 CAK77_RS16950 69f9a184e7bdd6fdeda317cd788d475b 245 Gene3D G3DSA:1.20.120.450 4 131 6.7E-5 T 06-07-2017 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase CAK77_RS16950 69f9a184e7bdd6fdeda317cd788d475b 245 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 14 221 1.2E-20 T 06-07-2017 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type CAK77_RS16950 69f9a184e7bdd6fdeda317cd788d475b 245 SUPERFAMILY SSF109854 2 130 2.44E-14 T 06-07-2017 CAK77_RS16950 69f9a184e7bdd6fdeda317cd788d475b 245 Pfam PF07398 MDMPI C-terminal domain 142 237 3.9E-8 T 06-07-2017 IPR010872 MDMPI C-terminal CAK77_RS06470 59a1514cd506b4f5fa879b707cdffb52 214 SUPERFAMILY SSF53335 35 213 2.84E-28 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS06470 59a1514cd506b4f5fa879b707cdffb52 214 Pfam PF13489 Methyltransferase domain 21 185 5.2E-14 T 06-07-2017 CAK77_RS06470 59a1514cd506b4f5fa879b707cdffb52 214 Gene3D G3DSA:3.40.50.150 14 191 1.2E-20 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS07890 5557c237f573beffd8a4ec08a09f7177 251 SUPERFAMILY SSF51182 9 244 8.71E-48 T 06-07-2017 IPR011051 RmlC-like cupin domain CAK77_RS07890 5557c237f573beffd8a4ec08a09f7177 251 Pfam PF02678 Pirin 21 128 2.8E-26 T 06-07-2017 IPR003829 Pirin, N-terminal domain CAK77_RS07890 5557c237f573beffd8a4ec08a09f7177 251 PIRSF PIRSF006232 6 250 1.4E-38 T 06-07-2017 IPR012093 Pirin CAK77_RS07890 5557c237f573beffd8a4ec08a09f7177 251 Gene3D G3DSA:2.60.120.10 10 244 5.8E-46 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK77_RS01910 0032fff73b48d2b50be6b314c4a67715 283 SUPERFAMILY SSF54637 19 141 1.73E-24 T 06-07-2017 IPR029069 HotDog domain CAK77_RS01910 0032fff73b48d2b50be6b314c4a67715 283 Pfam PF01575 MaoC like domain 164 263 8.0E-22 T 06-07-2017 IPR002539 MaoC-like domain CAK77_RS01910 0032fff73b48d2b50be6b314c4a67715 283 Pfam PF13452 N-terminal half of MaoC dehydratase 18 122 2.5E-10 T 06-07-2017 CAK77_RS01910 0032fff73b48d2b50be6b314c4a67715 283 Gene3D G3DSA:3.10.129.10 15 136 5.4E-15 T 06-07-2017 IPR029069 HotDog domain CAK77_RS01910 0032fff73b48d2b50be6b314c4a67715 283 SUPERFAMILY SSF54637 168 276 1.15E-22 T 06-07-2017 IPR029069 HotDog domain CAK77_RS01910 0032fff73b48d2b50be6b314c4a67715 283 Gene3D G3DSA:3.10.129.10 137 281 2.0E-26 T 06-07-2017 IPR029069 HotDog domain CAK77_RS07030 3b0ee6dca7ce017392116c4b25469156 398 Pfam PF01757 Acyltransferase family 20 375 2.3E-28 T 06-07-2017 IPR002656 Acyltransferase 3 GO:0016747 CAK77_RS08460 7cc9b2662a30a207a3258ae4b13d4f6d 308 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 38 261 2.4E-43 T 06-07-2017 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 CAK77_RS08460 7cc9b2662a30a207a3258ae4b13d4f6d 308 Gene3D G3DSA:3.40.50.620 14 216 1.7E-48 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS08460 7cc9b2662a30a207a3258ae4b13d4f6d 308 Gene3D G3DSA:3.40.50.620 249 256 1.7E-48 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS08460 7cc9b2662a30a207a3258ae4b13d4f6d 308 PIRSF PIRSF002936 8 308 6.9E-130 T 06-07-2017 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 CAK77_RS08460 7cc9b2662a30a207a3258ae4b13d4f6d 308 SUPERFAMILY SSF52402 16 216 6.98E-63 T 06-07-2017 CAK77_RS08460 7cc9b2662a30a207a3258ae4b13d4f6d 308 TIGRFAM TIGR02039 CysD: sulfate adenylyltransferase, small subunit 17 308 3.7E-137 T 06-07-2017 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 CAK77_RS16090 91ff37a0006ee1a87a3370f7b2bbbcdf 287 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 68 79 9.7E-10 T 06-07-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CAK77_RS16090 91ff37a0006ee1a87a3370f7b2bbbcdf 287 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 142 155 9.7E-10 T 06-07-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CAK77_RS16090 91ff37a0006ee1a87a3370f7b2bbbcdf 287 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 116 133 9.7E-10 T 06-07-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CAK77_RS16090 91ff37a0006ee1a87a3370f7b2bbbcdf 287 SUPERFAMILY SSF56601 9 276 6.15E-58 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK77_RS16090 91ff37a0006ee1a87a3370f7b2bbbcdf 287 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 37 253 2.2E-33 T 06-07-2017 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 CAK77_RS16090 91ff37a0006ee1a87a3370f7b2bbbcdf 287 Gene3D G3DSA:3.40.710.10 33 277 2.4E-70 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK77_RS22555 4e4087ab722029b033b769139385455a 411 Pfam PF13527 Acetyltransferase (GNAT) domain 10 131 2.6E-27 T 06-07-2017 CAK77_RS22555 4e4087ab722029b033b769139385455a 411 Gene3D G3DSA:3.40.630.30 155 294 2.0E-21 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS22555 4e4087ab722029b033b769139385455a 411 SUPERFAMILY SSF55718 306 411 4.32E-23 T 06-07-2017 IPR003033 SCP2 sterol-binding domain CAK77_RS22555 4e4087ab722029b033b769139385455a 411 Pfam PF13530 Sterol carrier protein domain 182 405 9.3E-45 T 06-07-2017 IPR025559 Enhanced intracellular survival protein domain CAK77_RS22555 4e4087ab722029b033b769139385455a 411 Gene3D G3DSA:3.40.630.30 10 134 1.8E-21 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS22555 4e4087ab722029b033b769139385455a 411 SUPERFAMILY SSF55729 10 305 6.42E-50 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS22555 4e4087ab722029b033b769139385455a 411 Gene3D G3DSA:3.30.1050.10 308 399 1.7E-22 T 06-07-2017 IPR003033 SCP2 sterol-binding domain CAK77_RS22170 50a2e39d48fa5c96f5ca73f46ea0c367 188 TIGRFAM TIGR03086 TIGR03086: TIGR03086 family protein 13 180 1.3E-36 T 06-07-2017 IPR017520 Conserved hypothetical protein CHP03086 CAK77_RS22170 50a2e39d48fa5c96f5ca73f46ea0c367 188 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 11 180 4.0E-18 T 06-07-2017 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type CAK77_RS22170 50a2e39d48fa5c96f5ca73f46ea0c367 188 SUPERFAMILY SSF109854 4 128 2.47E-10 T 06-07-2017 CAK77_RS08380 4401569d7987cde69d7166cbc0e4ef67 656 Gene3D G3DSA:1.50.10.10 265 641 5.3E-88 T 06-07-2017 IPR012341 Six-hairpin glycosidase GO:0003824 CAK77_RS08380 4401569d7987cde69d7166cbc0e4ef67 656 Pfam PF00723 Glycosyl hydrolases family 15 268 580 2.5E-46 T 06-07-2017 IPR011613 Glycoside hydrolase family 15/Phosphorylase b kinase regulatory chain family Reactome: R-HSA-70221 CAK77_RS08380 4401569d7987cde69d7166cbc0e4ef67 656 SUPERFAMILY SSF48208 239 636 4.95E-95 T 06-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 CAK77_RS14350 1090f6d9ca3e06ff2b8ceb182bf0f120 130 SUPERFAMILY SSF51735 1 77 1.08E-8 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS14350 1090f6d9ca3e06ff2b8ceb182bf0f120 130 Pfam PF00107 Zinc-binding dehydrogenase 1 78 8.1E-9 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAK77_RS14350 1090f6d9ca3e06ff2b8ceb182bf0f120 130 Gene3D G3DSA:3.40.50.720 1 72 1.5E-9 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS15070 e5d0f563dd897fe6006b7de29da1d486 130 Pfam PF11298 Protein of unknown function (DUF3099) 15 86 3.2E-29 T 06-07-2017 IPR021449 Protein of unknown function DUF3099 CAK77_RS00515 21e2acdad3753f9d5401ce1b593be2de 276 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 274 6.3E-51 T 06-07-2017 CAK77_RS00515 21e2acdad3753f9d5401ce1b593be2de 276 TIGRFAM TIGR03971 SDR_subfam_1: SDR family mycofactocin-dependent oxidoreductase 5 275 4.0E-113 T 06-07-2017 IPR023985 Mycofactocin-dependent oxidoreductase CAK77_RS00515 21e2acdad3753f9d5401ce1b593be2de 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 142 158 4.9E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS00515 21e2acdad3753f9d5401ce1b593be2de 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 95 106 4.9E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS00515 21e2acdad3753f9d5401ce1b593be2de 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 4.9E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS00515 21e2acdad3753f9d5401ce1b593be2de 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 187 4.9E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS00515 21e2acdad3753f9d5401ce1b593be2de 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 189 206 4.9E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS00515 21e2acdad3753f9d5401ce1b593be2de 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 237 257 4.9E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS00515 21e2acdad3753f9d5401ce1b593be2de 276 Gene3D G3DSA:3.40.50.720 3 273 1.0E-77 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS00515 21e2acdad3753f9d5401ce1b593be2de 276 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 156 5.8E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS00515 21e2acdad3753f9d5401ce1b593be2de 276 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 168 187 5.8E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS00515 21e2acdad3753f9d5401ce1b593be2de 276 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 95 106 5.8E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS00515 21e2acdad3753f9d5401ce1b593be2de 276 SUPERFAMILY SSF51735 4 275 1.38E-71 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS00515 21e2acdad3753f9d5401ce1b593be2de 276 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 155 183 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK77_RS13745 9c0d0efd2d5a159b68e67fcd98ef11b7 307 Pfam PF00551 Formyl transferase 3 173 5.4E-31 T 06-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CAK77_RS13745 9c0d0efd2d5a159b68e67fcd98ef11b7 307 SUPERFAMILY SSF53328 2 205 5.23E-54 T 06-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CAK77_RS13745 9c0d0efd2d5a159b68e67fcd98ef11b7 307 Gene3D G3DSA:3.40.50.170 1 204 7.4E-55 T 06-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CAK77_RS13745 9c0d0efd2d5a159b68e67fcd98ef11b7 307 Pfam PF02911 Formyl transferase, C-terminal domain 203 298 5.7E-24 T 06-07-2017 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CAK77_RS13745 9c0d0efd2d5a159b68e67fcd98ef11b7 307 SUPERFAMILY SSF50486 204 304 4.4E-26 T 06-07-2017 IPR011034 Formyl transferase, C-terminal-like GO:0003824 CAK77_RS13745 9c0d0efd2d5a159b68e67fcd98ef11b7 307 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 2 300 5.2E-65 T 06-07-2017 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 CAK77_RS13745 9c0d0efd2d5a159b68e67fcd98ef11b7 307 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 1 301 30.688 T 06-07-2017 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 CAK77_RS13745 9c0d0efd2d5a159b68e67fcd98ef11b7 307 Gene3D G3DSA:3.10.25.10 207 303 2.4E-29 T 06-07-2017 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CAK77_RS10975 0c7daa17342246c4ada65ae151a7f062 49 Gene3D G3DSA:1.10.1220.10 4 46 1.2E-5 T 06-07-2017 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CAK77_RS10975 0c7daa17342246c4ada65ae151a7f062 49 SUPERFAMILY SSF47598 4 48 1.46E-8 T 06-07-2017 IPR010985 Ribbon-helix-helix GO:0006355 CAK77_RS10975 0c7daa17342246c4ada65ae151a7f062 49 Pfam PF01402 Ribbon-helix-helix protein, copG family 9 45 1.8E-7 T 06-07-2017 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 CAK77_RS10640 8fed892c19c0489011bc4f8cdeece3ed 330 Pfam PF13280 WYL domain 152 324 6.2E-29 T 06-07-2017 IPR026881 WYL domain CAK77_RS06960 bf11de965f265d9d5340f78748f134dc 213 Pfam PF13649 Methyltransferase domain 54 143 1.6E-21 T 06-07-2017 CAK77_RS06960 bf11de965f265d9d5340f78748f134dc 213 Gene3D G3DSA:3.40.50.150 14 199 1.5E-37 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS06960 bf11de965f265d9d5340f78748f134dc 213 SUPERFAMILY SSF53335 16 200 1.55E-37 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS23040 f1665a1316cdb2d1c487151982b7636f 221 Gene3D G3DSA:3.10.180.10 106 209 1.4E-7 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK77_RS23040 f1665a1316cdb2d1c487151982b7636f 221 SUPERFAMILY SSF54593 1 188 1.38E-15 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK77_RS18030 3c548919c5a0297fee77ba24ed846cb4 185 Pfam PF03703 Bacterial PH domain 82 153 2.7E-18 T 06-07-2017 IPR005182 Domain of unknown function DUF304 CAK77_RS06400 044d6a684b80905417c2dd980f5c2add 172 Pfam PF07681 DoxX 17 94 2.5E-6 T 06-07-2017 IPR032808 DoxX family CAK77_RS19745 98ef5d003250517ddee9475e52c96e0a 152 Gene3D G3DSA:1.20.1290.10 10 150 2.9E-41 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAK77_RS19745 98ef5d003250517ddee9475e52c96e0a 152 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 34 82 8.1E-17 T 06-07-2017 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CAK77_RS19745 98ef5d003250517ddee9475e52c96e0a 152 Pfam PF02627 Carboxymuconolactone decarboxylase family 23 99 1.3E-17 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CAK77_RS19745 98ef5d003250517ddee9475e52c96e0a 152 SUPERFAMILY SSF69118 13 149 6.94E-37 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAK77_RS14050 69d59571276ac93738902ba121878fb5 424 Pfam PF03129 Anticodon binding domain 330 418 4.4E-12 T 06-07-2017 IPR004154 Anticodon-binding CAK77_RS14050 69d59571276ac93738902ba121878fb5 424 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 8 408 1.7E-131 T 06-07-2017 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 CAK77_RS14050 69d59571276ac93738902ba121878fb5 424 Pfam PF13393 Histidyl-tRNA synthetase 11 310 8.5E-45 T 06-07-2017 CAK77_RS14050 69d59571276ac93738902ba121878fb5 424 Gene3D G3DSA:3.30.930.10 220 319 7.6E-85 T 06-07-2017 CAK77_RS14050 69d59571276ac93738902ba121878fb5 424 Gene3D G3DSA:3.30.930.10 6 186 7.6E-85 T 06-07-2017 CAK77_RS14050 69d59571276ac93738902ba121878fb5 424 PIRSF PIRSF001549 2 420 3.8E-105 T 06-07-2017 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 CAK77_RS14050 69d59571276ac93738902ba121878fb5 424 Gene3D G3DSA:3.40.50.800 328 417 8.1E-21 T 06-07-2017 IPR004154 Anticodon-binding CAK77_RS14050 69d59571276ac93738902ba121878fb5 424 SUPERFAMILY SSF55681 7 315 4.18E-85 T 06-07-2017 CAK77_RS14050 69d59571276ac93738902ba121878fb5 424 SUPERFAMILY SSF52954 327 419 2.72E-18 T 06-07-2017 IPR004154 Anticodon-binding CAK77_RS14050 69d59571276ac93738902ba121878fb5 424 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 4 418 30.989 T 06-07-2017 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 CAK77_RS19800 ba67f50d48c72e4a8d04a88f7f24e548 185 Gene3D G3DSA:2.60.120.10 46 175 1.8E-29 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK77_RS19800 ba67f50d48c72e4a8d04a88f7f24e548 185 Pfam PF07883 Cupin domain 61 129 3.0E-15 T 06-07-2017 IPR013096 Cupin 2, conserved barrel CAK77_RS19800 ba67f50d48c72e4a8d04a88f7f24e548 185 SUPERFAMILY SSF51182 16 161 3.24E-24 T 06-07-2017 IPR011051 RmlC-like cupin domain CAK77_RS23075 ddec7f86a100578e7112599092b6fe2e 160 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 62 127 8.4E-15 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CAK77_RS23075 ddec7f86a100578e7112599092b6fe2e 160 SUPERFAMILY SSF50475 64 133 3.93E-5 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS23075 ddec7f86a100578e7112599092b6fe2e 160 Pfam PF04075 Domain of unknown function (DUF385) 62 128 2.6E-14 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CAK77_RS23075 ddec7f86a100578e7112599092b6fe2e 160 Gene3D G3DSA:2.30.110.10 64 134 1.8E-5 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS13685 204a3f84a4dc6e5a31b3df438e7d4d5d 228 Pfam PF09203 MspA 64 225 6.6E-47 T 06-07-2017 IPR015286 Porin family, mycobacterial-type CAK77_RS13685 204a3f84a4dc6e5a31b3df438e7d4d5d 228 SUPERFAMILY SSF56959 56 227 6.54E-30 T 06-07-2017 IPR016183 Leukocidin/porin GO:0005576|GO:0051715 CAK77_RS13685 204a3f84a4dc6e5a31b3df438e7d4d5d 228 Gene3D G3DSA:2.60.40.1650 54 124 3.1E-44 T 06-07-2017 CAK77_RS13685 204a3f84a4dc6e5a31b3df438e7d4d5d 228 Gene3D G3DSA:2.60.40.1650 166 228 3.1E-44 T 06-07-2017 CAK77_RS13450 5d08c704a0b19500ff4c3419658d629f 150 TIGRFAM TIGR01994 SUF_scaf_2: SUF system FeS assembly protein, NifU family 3 139 6.6E-51 T 06-07-2017 CAK77_RS13450 5d08c704a0b19500ff4c3419658d629f 150 Gene3D G3DSA:3.90.1010.10 5 146 7.5E-46 T 06-07-2017 CAK77_RS13450 5d08c704a0b19500ff4c3419658d629f 150 Pfam PF01592 NifU-like N terminal domain 6 127 8.5E-30 T 06-07-2017 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 CAK77_RS13450 5d08c704a0b19500ff4c3419658d629f 150 SUPERFAMILY SSF82649 2 139 1.15E-46 T 06-07-2017 CAK77_RS18995 0a24b441881770d9df263561c3c5093c 105 Gene3D G3DSA:2.30.30.30 1 90 8.3E-28 T 06-07-2017 IPR014722 Ribosomal protein L2 domain 2 CAK77_RS18995 0a24b441881770d9df263561c3c5093c 105 ProSitePatterns PS01108 Ribosomal protein L24 signature. 6 23 - T 06-07-2017 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAK77_RS18995 0a24b441881770d9df263561c3c5093c 105 Pfam PF00467 KOW motif 5 36 5.1E-9 T 06-07-2017 IPR005824 KOW CAK77_RS18995 0a24b441881770d9df263561c3c5093c 105 SUPERFAMILY SSF50104 1 102 3.24E-30 T 06-07-2017 IPR008991 Translation protein SH3-like domain CAK77_RS18995 0a24b441881770d9df263561c3c5093c 105 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 1 99 20.761 T 06-07-2017 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS18995 0a24b441881770d9df263561c3c5093c 105 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 1 105 1.1E-36 T 06-07-2017 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS18995 0a24b441881770d9df263561c3c5093c 105 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 38 105 1.8E-23 T 06-07-2017 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS18995 0a24b441881770d9df263561c3c5093c 105 SMART SM00739 2 29 1.4E-4 T 06-07-2017 IPR005824 KOW CAK77_RS03545 b077b6d01471f10e08979e0f2a117511 268 Gene3D G3DSA:3.40.50.1820 40 263 8.7E-29 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS03545 b077b6d01471f10e08979e0f2a117511 268 SUPERFAMILY SSF53474 44 263 4.71E-26 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS19615 68c03c742287619e1f6d0d65f794fff2 268 Gene3D G3DSA:3.90.640.20 187 267 5.3E-10 T 06-07-2017 IPR021729 Domain of unknown function DUF3298 CAK77_RS19615 68c03c742287619e1f6d0d65f794fff2 268 Pfam PF11738 Protein of unknown function (DUF3298) 181 253 9.5E-8 T 06-07-2017 IPR021729 Domain of unknown function DUF3298 CAK77_RS10645 499c41e2ebac6383dbf084b322af3cc0 318 PIRSF PIRSF016838 1 318 1.4E-120 T 06-07-2017 IPR028349 Protein PafC CAK77_RS10645 499c41e2ebac6383dbf084b322af3cc0 318 Pfam PF13280 WYL domain 142 311 3.1E-33 T 06-07-2017 IPR026881 WYL domain CAK77_RS20340 cf0d076a1651ba255c05293ae37e88d5 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 1.6E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS20340 cf0d076a1651ba255c05293ae37e88d5 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 168 1.6E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS20340 cf0d076a1651ba255c05293ae37e88d5 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 1.6E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS20340 cf0d076a1651ba255c05293ae37e88d5 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 1.6E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS20340 cf0d076a1651ba255c05293ae37e88d5 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 139 1.6E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS20340 cf0d076a1651ba255c05293ae37e88d5 249 Gene3D G3DSA:3.40.50.720 6 234 1.8E-62 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS20340 cf0d076a1651ba255c05293ae37e88d5 249 SUPERFAMILY SSF51735 4 236 1.27E-61 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS20340 cf0d076a1651ba255c05293ae37e88d5 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 129 137 5.2E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS20340 cf0d076a1651ba255c05293ae37e88d5 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 5.2E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS20340 cf0d076a1651ba255c05293ae37e88d5 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 168 5.2E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS20340 cf0d076a1651ba255c05293ae37e88d5 249 Pfam PF00106 short chain dehydrogenase 10 187 4.0E-44 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS07540 554f75f3bac8166a6b4ad213c0dc435b 235 SUPERFAMILY SSF64288 62 234 1.3E-40 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CAK77_RS07540 554f75f3bac8166a6b4ad213c0dc435b 235 SUPERFAMILY SSF46785 6 75 2.52E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS07540 554f75f3bac8166a6b4ad213c0dc435b 235 Pfam PF00392 Bacterial regulatory proteins, gntR family 19 69 2.1E-12 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK77_RS07540 554f75f3bac8166a6b4ad213c0dc435b 235 Gene3D G3DSA:3.40.1410.10 68 234 1.9E-40 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CAK77_RS07540 554f75f3bac8166a6b4ad213c0dc435b 235 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 30 44 3.6E-9 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK77_RS07540 554f75f3bac8166a6b4ad213c0dc435b 235 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 44 60 3.6E-9 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK77_RS07540 554f75f3bac8166a6b4ad213c0dc435b 235 Pfam PF07702 UTRA domain 89 227 7.4E-31 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CAK77_RS07540 554f75f3bac8166a6b4ad213c0dc435b 235 SMART SM00866 89 228 3.1E-30 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CAK77_RS07540 554f75f3bac8166a6b4ad213c0dc435b 235 SMART SM00345 13 69 9.8E-10 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK77_RS07540 554f75f3bac8166a6b4ad213c0dc435b 235 Gene3D G3DSA:1.10.10.10 6 67 2.3E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS11640 779faceed0174afba595ae350ea4cf59 198 PIRSF PIRSF000847 11 197 1.9E-42 T 06-07-2017 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668 CAK77_RS11640 779faceed0174afba595ae350ea4cf59 198 Pfam PF01066 CDP-alcohol phosphatidyltransferase 16 80 7.5E-15 T 06-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CAK77_RS11640 779faceed0174afba595ae350ea4cf59 198 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 58 80 - T 06-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CAK77_RS02535 1067c42c91e7c4844a7b2329c9c87184 319 SUPERFAMILY SSF53474 48 306 2.92E-35 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS02535 1067c42c91e7c4844a7b2329c9c87184 319 Gene3D G3DSA:3.40.50.1820 66 304 1.4E-36 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS02535 1067c42c91e7c4844a7b2329c9c87184 319 Pfam PF07859 alpha/beta hydrolase fold 86 282 3.6E-32 T 06-07-2017 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CAK77_RS23335 fecab52a72ed7d5460db5261457f8c18 205 SUPERFAMILY SSF53756 2 204 4.19E-54 T 06-07-2017 CAK77_RS23335 fecab52a72ed7d5460db5261457f8c18 205 Gene3D G3DSA:3.40.50.2000 22 185 9.6E-57 T 06-07-2017 CAK77_RS23335 fecab52a72ed7d5460db5261457f8c18 205 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 63 186 3.3E-8 T 06-07-2017 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 CAK77_RS21830 a736b1150fe22314bdddb8808edd4d5d 154 Gene3D G3DSA:3.30.530.20 9 152 9.5E-11 T 06-07-2017 IPR023393 START-like domain CAK77_RS21830 a736b1150fe22314bdddb8808edd4d5d 154 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 12 152 6.0E-13 T 06-07-2017 IPR019587 Polyketide cyclase/dehydrase CAK77_RS21830 a736b1150fe22314bdddb8808edd4d5d 154 SUPERFAMILY SSF55961 5 152 1.4E-23 T 06-07-2017 CAK77_RS22180 76f75d80fbe330a2df0b4ca96506ea17 590 Pfam PF01740 STAS domain 455 554 1.8E-10 T 06-07-2017 IPR002645 STAS domain CAK77_RS22180 76f75d80fbe330a2df0b4ca96506ea17 590 Gene3D G3DSA:3.30.750.24 456 555 3.3E-11 T 06-07-2017 IPR002645 STAS domain CAK77_RS22180 76f75d80fbe330a2df0b4ca96506ea17 590 Pfam PF00916 Sulfate permease family 18 396 2.2E-87 T 06-07-2017 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 CAK77_RS22180 76f75d80fbe330a2df0b4ca96506ea17 590 SUPERFAMILY SSF52091 456 551 7.46E-13 T 06-07-2017 IPR002645 STAS domain CAK77_RS01595 cf9481aef05f9e6904246955ae66281c 324 SUPERFAMILY SSF56112 3 301 8.36E-49 T 06-07-2017 IPR011009 Protein kinase-like domain CAK77_RS01595 cf9481aef05f9e6904246955ae66281c 324 Gene3D G3DSA:3.90.1200.10 143 246 2.4E-11 T 06-07-2017 CAK77_RS01595 cf9481aef05f9e6904246955ae66281c 324 Pfam PF01636 Phosphotransferase enzyme family 22 247 2.6E-16 T 06-07-2017 IPR002575 Aminoglycoside phosphotransferase CAK77_RS13050 98a43035f8d84aabaae013dd2b25c943 152 Pfam PF00578 AhpC/TSA family 4 127 2.2E-32 T 06-07-2017 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CAK77_RS13050 98a43035f8d84aabaae013dd2b25c943 152 PIRSF PIRSF000239 1 151 7.0E-21 T 06-07-2017 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CAK77_RS13050 98a43035f8d84aabaae013dd2b25c943 152 SUPERFAMILY SSF52833 2 150 9.92E-44 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK77_RS13050 98a43035f8d84aabaae013dd2b25c943 152 Gene3D G3DSA:3.40.30.10 2 150 4.1E-40 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK77_RS17200 bb603dfbe2f0c51a37f882fb7150eda2 107 Pfam PF01906 Putative heavy-metal-binding 1 102 5.9E-34 T 06-07-2017 IPR002765 Uncharacterised protein family UPF0145 CAK77_RS17200 bb603dfbe2f0c51a37f882fb7150eda2 107 SUPERFAMILY SSF117782 1 105 7.46E-34 T 06-07-2017 IPR002765 Uncharacterised protein family UPF0145 CAK77_RS17200 bb603dfbe2f0c51a37f882fb7150eda2 107 Gene3D G3DSA:3.30.110.70 1 101 1.3E-33 T 06-07-2017 IPR002765 Uncharacterised protein family UPF0145 CAK77_RS17200 bb603dfbe2f0c51a37f882fb7150eda2 107 Hamap MF_00338 UPF0145 protein YbjQ [ybjQ]. 1 103 21.886 T 06-07-2017 IPR002765 Uncharacterised protein family UPF0145 CAK77_RS21425 437b3f1dbce754a0f2edcc737d7576d8 932 SUPERFAMILY SSF82866 710 921 5.1E-19 T 06-07-2017 CAK77_RS21425 437b3f1dbce754a0f2edcc737d7576d8 932 SUPERFAMILY SSF82866 146 345 6.41E-28 T 06-07-2017 CAK77_RS21425 437b3f1dbce754a0f2edcc737d7576d8 932 Gene3D G3DSA:1.20.1640.10 145 355 1.4E-31 T 06-07-2017 CAK77_RS21425 437b3f1dbce754a0f2edcc737d7576d8 932 Gene3D G3DSA:1.20.1640.10 756 922 1.2E-14 T 06-07-2017 CAK77_RS21425 437b3f1dbce754a0f2edcc737d7576d8 932 Pfam PF03176 MMPL family 50 380 3.0E-81 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 CAK77_RS21425 437b3f1dbce754a0f2edcc737d7576d8 932 Pfam PF03176 MMPL family 615 923 1.2E-66 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 CAK77_RS18090 29e3468a2c665abfc9fd154db60ce3b2 462 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 26 462 5.4E-123 T 06-07-2017 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 CAK77_RS18090 29e3468a2c665abfc9fd154db60ce3b2 462 PIRSF PIRSF002746 18 462 3.2E-137 T 06-07-2017 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 CAK77_RS18090 29e3468a2c665abfc9fd154db60ce3b2 462 Pfam PF02447 GntP family permease 24 460 1.7E-131 T 06-07-2017 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 CAK77_RS09870 c6916a41ff09ddccaff13b6d7f6e3878 249 Pfam PF00975 Thioesterase domain 25 235 2.8E-39 T 06-07-2017 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 CAK77_RS09870 c6916a41ff09ddccaff13b6d7f6e3878 249 SUPERFAMILY SSF53474 3 242 5.4E-47 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS09870 c6916a41ff09ddccaff13b6d7f6e3878 249 Gene3D G3DSA:3.40.50.1820 16 242 7.4E-31 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS10430 6312466104fff2878d7faa47dc7c5d1a 621 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 261 283 1.3E-14 T 06-07-2017 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 CAK77_RS10430 6312466104fff2878d7faa47dc7c5d1a 621 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 57 81 1.3E-14 T 06-07-2017 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 CAK77_RS10430 6312466104fff2878d7faa47dc7c5d1a 621 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 417 439 1.3E-14 T 06-07-2017 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 CAK77_RS10430 6312466104fff2878d7faa47dc7c5d1a 621 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 83 103 1.3E-14 T 06-07-2017 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 CAK77_RS10430 6312466104fff2878d7faa47dc7c5d1a 621 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 3 616 2.8E-226 T 06-07-2017 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS10430 6312466104fff2878d7faa47dc7c5d1a 621 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 109 129 8.5E-64 T 06-07-2017 CAK77_RS10430 6312466104fff2878d7faa47dc7c5d1a 621 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 243 269 8.5E-64 T 06-07-2017 CAK77_RS10430 6312466104fff2878d7faa47dc7c5d1a 621 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 221 242 8.5E-64 T 06-07-2017 CAK77_RS10430 6312466104fff2878d7faa47dc7c5d1a 621 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 156 177 8.5E-64 T 06-07-2017 CAK77_RS10430 6312466104fff2878d7faa47dc7c5d1a 621 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 418 437 8.5E-64 T 06-07-2017 CAK77_RS10430 6312466104fff2878d7faa47dc7c5d1a 621 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 311 323 8.5E-64 T 06-07-2017 CAK77_RS10430 6312466104fff2878d7faa47dc7c5d1a 621 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 81 106 8.5E-64 T 06-07-2017 CAK77_RS10430 6312466104fff2878d7faa47dc7c5d1a 621 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 63 120 4.0E-25 T 06-07-2017 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS10430 6312466104fff2878d7faa47dc7c5d1a 621 Pfam PF00361 Proton-conducting membrane transporter 132 409 1.8E-83 T 06-07-2017 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS05105 2d53881a2c1d6e2b43df54fdfcc2009f 334 SUPERFAMILY SSF53756 2 330 1.0E-9 T 06-07-2017 CAK77_RS05105 2d53881a2c1d6e2b43df54fdfcc2009f 334 Pfam PF13524 Glycosyl transferases group 1 240 330 1.0E-20 T 06-07-2017 CAK77_RS01720 97dae458004d8a31a3c4e536eb1ff86f 199 Gene3D G3DSA:1.10.357.10 4 133 5.0E-23 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS01720 97dae458004d8a31a3c4e536eb1ff86f 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 59 1.8E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS01720 97dae458004d8a31a3c4e536eb1ff86f 199 SUPERFAMILY SSF46689 6 79 7.48E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS05130 e6d59201bc84a3e24f9cfee16b8693ce 488 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 33 488 6.6E-108 T 06-07-2017 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase CAK77_RS05130 e6d59201bc84a3e24f9cfee16b8693ce 488 Pfam PF02397 Bacterial sugar transferase 295 482 5.5E-56 T 06-07-2017 IPR003362 Bacterial sugar transferase CAK77_RS05000 a1188ae60565d552ab144dbffa575d40 293 SUPERFAMILY SSF51735 1 278 1.02E-41 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS05000 a1188ae60565d552ab144dbffa575d40 293 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 81 2.2E-11 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 CAK77_RS05000 a1188ae60565d552ab144dbffa575d40 293 Gene3D G3DSA:3.40.50.720 1 277 4.3E-36 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS07055 1948f86f01d31f2cdfc30f03a04d8cf9 423 ProSitePatterns PS00216 Sugar transport proteins signature 1. 72 88 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CAK77_RS07055 1948f86f01d31f2cdfc30f03a04d8cf9 423 SUPERFAMILY SSF103473 16 406 2.88E-45 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK77_RS07055 1948f86f01d31f2cdfc30f03a04d8cf9 423 Pfam PF05977 Transmembrane secretion effector 23 418 9.2E-30 T 06-07-2017 IPR010290 Transmembrane secretion effector CAK77_RS07055 1948f86f01d31f2cdfc30f03a04d8cf9 423 Gene3D G3DSA:1.20.1250.20 251 417 5.3E-22 T 06-07-2017 CAK77_RS07055 1948f86f01d31f2cdfc30f03a04d8cf9 423 PRINTS PR01988 Putative bacilysin exporter bacE signature 310 333 7.1E-5 T 06-07-2017 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CAK77_RS07055 1948f86f01d31f2cdfc30f03a04d8cf9 423 PRINTS PR01988 Putative bacilysin exporter bacE signature 21 43 7.1E-5 T 06-07-2017 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CAK77_RS07055 1948f86f01d31f2cdfc30f03a04d8cf9 423 PRINTS PR01988 Putative bacilysin exporter bacE signature 152 173 7.1E-5 T 06-07-2017 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CAK77_RS07055 1948f86f01d31f2cdfc30f03a04d8cf9 423 Gene3D G3DSA:1.20.1250.20 19 208 2.5E-14 T 06-07-2017 CAK77_RS19810 7e4c861e1618a4a4f7352ac0a42390ae 165 SUPERFAMILY SSF50475 22 158 1.14E-25 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS19810 7e4c861e1618a4a4f7352ac0a42390ae 165 Gene3D G3DSA:2.30.110.10 20 162 3.0E-36 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS19810 7e4c861e1618a4a4f7352ac0a42390ae 165 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 26 105 6.1E-14 T 06-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAK77_RS14215 1509f75d95d5462947e2e452a96f60da 140 Gene3D G3DSA:2.30.110.10 3 135 1.3E-22 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS14215 1509f75d95d5462947e2e452a96f60da 140 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 7 135 1.9E-28 T 06-07-2017 IPR019920 F420-binding domain, putative CAK77_RS14215 1509f75d95d5462947e2e452a96f60da 140 SUPERFAMILY SSF50475 3 136 9.11E-22 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS14215 1509f75d95d5462947e2e452a96f60da 140 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 5 96 1.3E-11 T 06-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAK77_RS08575 34d51cc1c22670593385ffe5e984616f 326 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 229 4.4E-27 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 CAK77_RS08575 34d51cc1c22670593385ffe5e984616f 326 SUPERFAMILY SSF51735 3 267 6.86E-52 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS08575 34d51cc1c22670593385ffe5e984616f 326 SUPERFAMILY SSF51735 298 325 6.86E-52 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS08575 34d51cc1c22670593385ffe5e984616f 326 Gene3D G3DSA:3.40.50.720 4 325 2.4E-52 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS18055 0c01314228a1aa22705ddc7f20ffb21f 340 Gene3D G3DSA:1.10.10.10 271 312 8.2E-5 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS18055 0c01314228a1aa22705ddc7f20ffb21f 340 Pfam PF13556 PucR C-terminal helix-turn-helix domain 271 326 3.2E-12 T 06-07-2017 IPR025736 PucR C-terminal helix-turn-helix domain CAK77_RS00830 cc2915c6ee71309db7fe9cdb3fed756c 239 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 16 215 4.9E-45 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 CAK77_RS00830 cc2915c6ee71309db7fe9cdb3fed756c 239 SMART SM00855 15 175 7.4E-18 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 CAK77_RS00830 cc2915c6ee71309db7fe9cdb3fed756c 239 Gene3D G3DSA:3.40.50.1240 15 215 3.2E-44 T 06-07-2017 IPR029033 Histidine phosphatase superfamily CAK77_RS00830 cc2915c6ee71309db7fe9cdb3fed756c 239 SUPERFAMILY SSF53254 12 215 6.34E-48 T 06-07-2017 IPR029033 Histidine phosphatase superfamily CAK77_RS23420 e32f10b154855fb5043efb95b6cfd1c7 948 SUPERFAMILY SSF82866 690 923 3.66E-27 T 06-07-2017 CAK77_RS23420 e32f10b154855fb5043efb95b6cfd1c7 948 SUPERFAMILY SSF82866 148 344 1.2E-26 T 06-07-2017 CAK77_RS23420 e32f10b154855fb5043efb95b6cfd1c7 948 TIGRFAM TIGR00833 actII: transport protein 14 923 0.0 T 06-07-2017 IPR004707 Membrane transport protein MmpL family GO:0016021 CAK77_RS23420 e32f10b154855fb5043efb95b6cfd1c7 948 Gene3D G3DSA:1.20.1640.10 146 350 4.8E-28 T 06-07-2017 CAK77_RS23420 e32f10b154855fb5043efb95b6cfd1c7 948 Gene3D G3DSA:1.20.1640.10 718 926 2.5E-25 T 06-07-2017 CAK77_RS23420 e32f10b154855fb5043efb95b6cfd1c7 948 Pfam PF03176 MMPL family 603 931 9.9E-104 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 CAK77_RS23420 e32f10b154855fb5043efb95b6cfd1c7 948 Pfam PF03176 MMPL family 48 376 6.5E-114 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 CAK77_RS17135 476af785032f38e00287f8c8a4d57d18 307 Pfam PF00106 short chain dehydrogenase 12 203 3.9E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS17135 476af785032f38e00287f8c8a4d57d18 307 SUPERFAMILY SSF51735 6 261 3.58E-49 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS17135 476af785032f38e00287f8c8a4d57d18 307 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 157 185 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK77_RS17135 476af785032f38e00287f8c8a4d57d18 307 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 161 5.2E-20 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS17135 476af785032f38e00287f8c8a4d57d18 307 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 189 5.2E-20 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS17135 476af785032f38e00287f8c8a4d57d18 307 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 5.2E-20 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS17135 476af785032f38e00287f8c8a4d57d18 307 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 191 208 5.2E-20 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS17135 476af785032f38e00287f8c8a4d57d18 307 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 97 108 5.2E-20 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS17135 476af785032f38e00287f8c8a4d57d18 307 Gene3D G3DSA:3.40.50.720 6 260 1.1E-52 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS17135 476af785032f38e00287f8c8a4d57d18 307 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 159 3.7E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS17135 476af785032f38e00287f8c8a4d57d18 307 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 97 108 3.7E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS17135 476af785032f38e00287f8c8a4d57d18 307 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 170 189 3.7E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS03420 cf02b8a4da45b7851b8d713bf2099334 184 ProDom PD103079 MB0101 RV0098/MT0107 ML1993 16 184 7.0E-66 T 06-07-2017 IPR022598 Long-chain fatty acyl-CoA thioesterase, Rv0098-like CAK77_RS03420 cf02b8a4da45b7851b8d713bf2099334 184 Pfam PF10862 FcoT-like thioesterase domain 29 180 2.4E-62 T 06-07-2017 IPR022598 Long-chain fatty acyl-CoA thioesterase, Rv0098-like CAK77_RS07775 f16551f46442fe0c9b7927ee0f2c045b 113 Pfam PF05305 Protein of unknown function (DUF732) 11 102 1.2E-20 T 06-07-2017 IPR007969 Domain of unknown function DUF732 CAK77_RS06505 2cc77a3d6ee99d6103f0d31ce2fa4e76 152 Gene3D G3DSA:1.10.260.40 93 146 8.0E-6 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK77_RS16800 9c811b043f7f330840617892f28716cc 249 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 164 198 6.5E-8 T 06-07-2017 IPR001451 Hexapeptide repeat CAK77_RS16800 9c811b043f7f330840617892f28716cc 249 Gene3D G3DSA:2.160.10.10 70 240 4.5E-30 T 06-07-2017 CAK77_RS16800 9c811b043f7f330840617892f28716cc 249 SUPERFAMILY SSF51161 38 221 1.04E-28 T 06-07-2017 IPR011004 Trimeric LpxA-like CAK77_RS22135 9305e1be5efa61fe19d0b89394fca050 317 Pfam PF12146 Serine aminopeptidase, S33 55 299 1.1E-16 T 06-07-2017 IPR022742 Serine aminopeptidase, S33 CAK77_RS22135 9305e1be5efa61fe19d0b89394fca050 317 Gene3D G3DSA:3.40.50.1820 54 313 1.8E-30 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS22135 9305e1be5efa61fe19d0b89394fca050 317 SUPERFAMILY SSF53474 29 162 2.41E-32 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS22135 9305e1be5efa61fe19d0b89394fca050 317 SUPERFAMILY SSF53474 242 314 2.41E-32 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS08780 1b7b656ae5cde90b5b5ded29d3bc714a 227 SUPERFAMILY SSF52172 3 181 5.41E-42 T 06-07-2017 IPR011006 CheY-like superfamily CAK77_RS08780 1b7b656ae5cde90b5b5ded29d3bc714a 227 SMART SM00448 5 115 9.6E-42 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK77_RS08780 1b7b656ae5cde90b5b5ded29d3bc714a 227 Pfam PF00072 Response regulator receiver domain 7 115 2.2E-27 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAK77_RS08780 1b7b656ae5cde90b5b5ded29d3bc714a 227 SMART SM00862 150 223 4.2E-26 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAK77_RS08780 1b7b656ae5cde90b5b5ded29d3bc714a 227 Gene3D G3DSA:1.10.10.10 129 226 3.7E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS08780 1b7b656ae5cde90b5b5ded29d3bc714a 227 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 223 3.0E-22 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAK77_RS08780 1b7b656ae5cde90b5b5ded29d3bc714a 227 Gene3D G3DSA:3.40.50.2300 3 126 1.3E-38 T 06-07-2017 CAK77_RS23425 7824f193f6b9ca03dd9679cef322bd73 967 TIGRFAM TIGR00833 actII: transport protein 27 937 0.0 T 06-07-2017 IPR004707 Membrane transport protein MmpL family GO:0016021 CAK77_RS23425 7824f193f6b9ca03dd9679cef322bd73 967 SUPERFAMILY SSF82866 156 357 5.1E-26 T 06-07-2017 CAK77_RS23425 7824f193f6b9ca03dd9679cef322bd73 967 Pfam PF03176 MMPL family 61 389 1.4E-101 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 CAK77_RS23425 7824f193f6b9ca03dd9679cef322bd73 967 Pfam PF03176 MMPL family 610 945 1.1E-102 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 CAK77_RS23425 7824f193f6b9ca03dd9679cef322bd73 967 SUPERFAMILY SSF82866 689 937 2.49E-30 T 06-07-2017 CAK77_RS23425 7824f193f6b9ca03dd9679cef322bd73 967 Gene3D G3DSA:1.20.1640.10 752 940 4.9E-24 T 06-07-2017 CAK77_RS23425 7824f193f6b9ca03dd9679cef322bd73 967 Gene3D G3DSA:1.20.1640.10 152 362 3.3E-28 T 06-07-2017 CAK77_RS13060 9bf20736b53fb5e1c1a77144bcf7427f 257 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 2 257 47.472 T 06-07-2017 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 CAK77_RS13060 9bf20736b53fb5e1c1a77144bcf7427f 257 Gene3D G3DSA:3.20.20.70 6 257 2.5E-100 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK77_RS13060 9bf20736b53fb5e1c1a77144bcf7427f 257 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 3 257 2.1E-111 T 06-07-2017 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 CAK77_RS13060 9bf20736b53fb5e1c1a77144bcf7427f 257 SUPERFAMILY SSF51366 4 257 1.49E-77 T 06-07-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CAK77_RS13060 9bf20736b53fb5e1c1a77144bcf7427f 257 Pfam PF00977 Histidine biosynthesis protein 6 241 2.7E-84 T 06-07-2017 IPR006062 Histidine biosynthesis GO:0000105 CAK77_RS10535 6ead615c380d2c7dffa7311618964a31 245 Pfam PF13490 Putative zinc-finger 13 38 3.6E-5 T 06-07-2017 IPR027383 Putative zinc-finger CAK77_RS07500 307e5fdfc5689b9b4a551a74f8a42e11 486 Pfam PF11855 Protein of unknown function (DUF3375) 16 471 5.1E-106 T 06-07-2017 IPR021804 Protein of unknown function DUF3375 CAK77_RS21040 991a1dfe74eb45f7907a341da7c6d89c 210 Gene3D G3DSA:3.40.50.1820 9 194 1.1E-23 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS21040 991a1dfe74eb45f7907a341da7c6d89c 210 SUPERFAMILY SSF53474 8 202 2.68E-27 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS08205 b51d5f6ba2dcd0afd0a2d26233cc5c13 136 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 114 122 - T 06-07-2017 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CAK77_RS08205 b51d5f6ba2dcd0afd0a2d26233cc5c13 136 SMART SM00562 2 136 1.4E-70 T 06-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CAK77_RS08205 b51d5f6ba2dcd0afd0a2d26233cc5c13 136 Pfam PF00334 Nucleoside diphosphate kinase 3 134 1.8E-51 T 06-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CAK77_RS08205 b51d5f6ba2dcd0afd0a2d26233cc5c13 136 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 2 136 33.387 T 06-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CAK77_RS08205 b51d5f6ba2dcd0afd0a2d26233cc5c13 136 PRINTS PR01243 Nucleoside diphosphate kinase signature 69 86 2.3E-41 T 06-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CAK77_RS08205 b51d5f6ba2dcd0afd0a2d26233cc5c13 136 PRINTS PR01243 Nucleoside diphosphate kinase signature 5 27 2.3E-41 T 06-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CAK77_RS08205 b51d5f6ba2dcd0afd0a2d26233cc5c13 136 PRINTS PR01243 Nucleoside diphosphate kinase signature 114 133 2.3E-41 T 06-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CAK77_RS08205 b51d5f6ba2dcd0afd0a2d26233cc5c13 136 PRINTS PR01243 Nucleoside diphosphate kinase signature 49 68 2.3E-41 T 06-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CAK77_RS08205 b51d5f6ba2dcd0afd0a2d26233cc5c13 136 PRINTS PR01243 Nucleoside diphosphate kinase signature 91 107 2.3E-41 T 06-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CAK77_RS08205 b51d5f6ba2dcd0afd0a2d26233cc5c13 136 Gene3D G3DSA:3.30.70.141 2 134 1.7E-53 T 06-07-2017 CAK77_RS08205 b51d5f6ba2dcd0afd0a2d26233cc5c13 136 SUPERFAMILY SSF54919 2 135 2.88E-51 T 06-07-2017 CAK77_RS21340 2e42e832ef459b6931555378fc63787f 181 Gene3D G3DSA:1.10.10.10 118 179 1.2E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS21340 2e42e832ef459b6931555378fc63787f 181 SUPERFAMILY SSF88946 5 92 3.4E-20 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS21340 2e42e832ef459b6931555378fc63787f 181 SUPERFAMILY SSF88659 115 179 1.33E-13 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS21340 2e42e832ef459b6931555378fc63787f 181 Pfam PF04545 Sigma-70, region 4 127 176 1.4E-12 T 06-07-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS21340 2e42e832ef459b6931555378fc63787f 181 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 18 178 3.4E-23 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS21340 2e42e832ef459b6931555378fc63787f 181 Pfam PF04542 Sigma-70 region 2 23 91 4.3E-16 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAK77_RS21340 2e42e832ef459b6931555378fc63787f 181 Gene3D G3DSA:1.10.1740.10 6 105 2.7E-20 T 06-07-2017 CAK77_RS06455 d64d2439efc8fca1f56cdd7edc745533 211 SUPERFAMILY SSF48498 88 192 6.92E-16 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS06455 d64d2439efc8fca1f56cdd7edc745533 211 Gene3D G3DSA:1.10.357.10 6 191 2.4E-37 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS06455 d64d2439efc8fca1f56cdd7edc745533 211 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 66 1.5E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS06455 d64d2439efc8fca1f56cdd7edc745533 211 SUPERFAMILY SSF46689 8 92 1.36E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS06455 d64d2439efc8fca1f56cdd7edc745533 211 Pfam PF13305 WHG domain 94 173 1.5E-13 T 06-07-2017 IPR025996 WHG domain CAK77_RS14355 f50abeee13b01706583c714742c7d2ad 266 Pfam PF01145 SPFH domain / Band 7 family 26 196 2.3E-35 T 06-07-2017 IPR001107 Band 7 domain CAK77_RS14355 f50abeee13b01706583c714742c7d2ad 266 SUPERFAMILY SSF117892 53 186 1.83E-37 T 06-07-2017 IPR001107 Band 7 domain CAK77_RS14355 f50abeee13b01706583c714742c7d2ad 266 PRINTS PR00721 Stomatin signature 76 97 9.9E-61 T 06-07-2017 IPR001972 Stomatin family GO:0016020 CAK77_RS14355 f50abeee13b01706583c714742c7d2ad 266 PRINTS PR00721 Stomatin signature 131 154 9.9E-61 T 06-07-2017 IPR001972 Stomatin family GO:0016020 CAK77_RS14355 f50abeee13b01706583c714742c7d2ad 266 PRINTS PR00721 Stomatin signature 155 173 9.9E-61 T 06-07-2017 IPR001972 Stomatin family GO:0016020 CAK77_RS14355 f50abeee13b01706583c714742c7d2ad 266 PRINTS PR00721 Stomatin signature 174 195 9.9E-61 T 06-07-2017 IPR001972 Stomatin family GO:0016020 CAK77_RS14355 f50abeee13b01706583c714742c7d2ad 266 PRINTS PR00721 Stomatin signature 111 128 9.9E-61 T 06-07-2017 IPR001972 Stomatin family GO:0016020 CAK77_RS14355 f50abeee13b01706583c714742c7d2ad 266 PRINTS PR00721 Stomatin signature 199 222 9.9E-61 T 06-07-2017 IPR001972 Stomatin family GO:0016020 CAK77_RS14355 f50abeee13b01706583c714742c7d2ad 266 PRINTS PR00721 Stomatin signature 29 51 9.9E-61 T 06-07-2017 IPR001972 Stomatin family GO:0016020 CAK77_RS14355 f50abeee13b01706583c714742c7d2ad 266 SMART SM00244 22 179 3.3E-54 T 06-07-2017 IPR001107 Band 7 domain CAK77_RS07515 4209f8210584391f56e8787aaf47f080 261 SUPERFAMILY SSF52096 1 261 7.05E-64 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS07515 4209f8210584391f56e8787aaf47f080 261 Gene3D G3DSA:3.90.226.10 2 258 5.4E-62 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS07515 4209f8210584391f56e8787aaf47f080 261 Pfam PF00378 Enoyl-CoA hydratase/isomerase 14 259 8.9E-46 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAK77_RS10060 bfe3653c5921cc2be371bf330063412c 307 SUPERFAMILY SSF47240 10 226 2.13E-39 T 06-07-2017 IPR009078 Ferritin-like superfamily CAK77_RS20915 0f686f9685b7380d2c1eb333685107c1 400 SUPERFAMILY SSF55961 124 344 7.69E-31 T 06-07-2017 CAK77_RS20915 0f686f9685b7380d2c1eb333685107c1 400 Pfam PF00355 Rieske [2Fe-2S] domain 26 110 7.6E-18 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK77_RS20915 0f686f9685b7380d2c1eb333685107c1 400 SUPERFAMILY SSF50022 18 131 3.67E-28 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK77_RS20915 0f686f9685b7380d2c1eb333685107c1 400 Gene3D G3DSA:2.102.10.10 24 136 2.3E-30 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK77_RS17970 140345c236e31cc7211cb45b7604a8a0 304 Pfam PF00535 Glycosyl transferase family 2 18 199 4.1E-18 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CAK77_RS17970 140345c236e31cc7211cb45b7604a8a0 304 SUPERFAMILY SSF53448 16 245 1.42E-45 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK77_RS17970 140345c236e31cc7211cb45b7604a8a0 304 Gene3D G3DSA:3.90.550.10 16 242 3.2E-39 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK77_RS17980 c5799773c761359b0dafea707908c95f 501 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 106 274 5.5E-32 T 06-07-2017 IPR004474 Cell envelope-related transcriptional attenuator domain CAK77_RS17980 c5799773c761359b0dafea707908c95f 501 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 106 274 9.7E-42 T 06-07-2017 IPR004474 Cell envelope-related transcriptional attenuator domain CAK77_RS17980 c5799773c761359b0dafea707908c95f 501 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 376 459 6.9E-13 T 06-07-2017 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain CAK77_RS04725 19aa91fef52411986bc5a8f25a8838b5 225 SUPERFAMILY SSF53335 2 189 1.45E-38 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS04725 19aa91fef52411986bc5a8f25a8838b5 225 Gene3D G3DSA:3.40.50.150 25 193 3.7E-38 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS04725 19aa91fef52411986bc5a8f25a8838b5 225 Pfam PF13649 Methyltransferase domain 48 141 5.7E-18 T 06-07-2017 CAK77_RS07645 1cfaadb754ad7f3d22539f86d3dbd94a 208 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 61 3.3E-16 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS07645 1cfaadb754ad7f3d22539f86d3dbd94a 208 SUPERFAMILY SSF46689 6 78 7.7E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS07645 1cfaadb754ad7f3d22539f86d3dbd94a 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 1.4E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS07645 1cfaadb754ad7f3d22539f86d3dbd94a 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 1.4E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS07645 1cfaadb754ad7f3d22539f86d3dbd94a 208 ProSitePatterns PS01081 TetR-type HTH domain signature. 27 57 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CAK77_RS07645 1cfaadb754ad7f3d22539f86d3dbd94a 208 Gene3D G3DSA:1.10.357.10 10 196 1.5E-24 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS10785 b444b8108abae5d82902067c062fb4d1 263 SUPERFAMILY SSF53474 4 250 7.95E-28 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS10785 b444b8108abae5d82902067c062fb4d1 263 Pfam PF00975 Thioesterase domain 25 248 3.8E-11 T 06-07-2017 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 CAK77_RS10785 b444b8108abae5d82902067c062fb4d1 263 Gene3D G3DSA:3.40.50.1820 194 245 6.4E-16 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS10785 b444b8108abae5d82902067c062fb4d1 263 Gene3D G3DSA:3.40.50.1820 19 127 6.4E-16 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS17120 ac50a0cef9d7ffcec8b14d1ed1cd4663 512 Gene3D G3DSA:3.40.50.980 6 163 3.6E-34 T 06-07-2017 CAK77_RS17120 ac50a0cef9d7ffcec8b14d1ed1cd4663 512 ProSitePatterns PS00455 Putative AMP-binding domain signature. 157 168 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK77_RS17120 ac50a0cef9d7ffcec8b14d1ed1cd4663 512 SUPERFAMILY SSF56801 6 509 6.02E-130 T 06-07-2017 CAK77_RS17120 ac50a0cef9d7ffcec8b14d1ed1cd4663 512 Gene3D G3DSA:2.30.38.10 336 404 4.0E-13 T 06-07-2017 CAK77_RS17120 ac50a0cef9d7ffcec8b14d1ed1cd4663 512 Pfam PF00501 AMP-binding enzyme 6 410 9.6E-73 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK77_RS17120 ac50a0cef9d7ffcec8b14d1ed1cd4663 512 Gene3D G3DSA:3.40.50.980 164 326 7.2E-37 T 06-07-2017 CAK77_RS17120 ac50a0cef9d7ffcec8b14d1ed1cd4663 512 Pfam PF13193 AMP-binding enzyme C-terminal domain 419 497 2.7E-19 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAK77_RS17120 ac50a0cef9d7ffcec8b14d1ed1cd4663 512 Gene3D G3DSA:3.30.300.30 406 508 1.2E-29 T 06-07-2017 CAK77_RS13340 3fa335d5d3f4f277c14844d309c7cb7d 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 126 134 2.0E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS13340 3fa335d5d3f4f277c14844d309c7cb7d 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 165 2.0E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS13340 3fa335d5d3f4f277c14844d309c7cb7d 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 73 84 2.0E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS13340 3fa335d5d3f4f277c14844d309c7cb7d 240 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 182 3.8E-5 T 06-07-2017 CAK77_RS13340 3fa335d5d3f4f277c14844d309c7cb7d 240 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 236 1.1E-57 T 06-07-2017 CAK77_RS13340 3fa335d5d3f4f277c14844d309c7cb7d 240 SUPERFAMILY SSF51735 9 236 1.11E-78 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS13340 3fa335d5d3f4f277c14844d309c7cb7d 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 7.4E-44 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS13340 3fa335d5d3f4f277c14844d309c7cb7d 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 120 136 7.4E-44 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS13340 3fa335d5d3f4f277c14844d309c7cb7d 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 200 220 7.4E-44 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS13340 3fa335d5d3f4f277c14844d309c7cb7d 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 184 7.4E-44 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS13340 3fa335d5d3f4f277c14844d309c7cb7d 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 73 84 7.4E-44 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS13340 3fa335d5d3f4f277c14844d309c7cb7d 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 146 165 7.4E-44 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS13340 3fa335d5d3f4f277c14844d309c7cb7d 240 Gene3D G3DSA:3.40.50.720 9 236 1.6E-79 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS04090 fe00f8822a36271a16981b85ca940fb1 285 Pfam PF00106 short chain dehydrogenase 6 208 2.1E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS04090 fe00f8822a36271a16981b85ca940fb1 285 SUPERFAMILY SSF51735 5 248 2.84E-54 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS04090 fe00f8822a36271a16981b85ca940fb1 285 Gene3D G3DSA:3.40.50.720 5 250 1.1E-56 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS04090 fe00f8822a36271a16981b85ca940fb1 285 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 168 187 2.5E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS04090 fe00f8822a36271a16981b85ca940fb1 285 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 2.5E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS04090 fe00f8822a36271a16981b85ca940fb1 285 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 2.5E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS04090 fe00f8822a36271a16981b85ca940fb1 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 4.6E-18 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS04090 fe00f8822a36271a16981b85ca940fb1 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 188 205 4.6E-18 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS04090 fe00f8822a36271a16981b85ca940fb1 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 187 4.6E-18 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS04090 fe00f8822a36271a16981b85ca940fb1 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 4.6E-18 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS04090 fe00f8822a36271a16981b85ca940fb1 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 4.6E-18 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS12850 49be78109ce97fcf8ca94d7cc049f0db 379 Pfam PF07690 Major Facilitator Superfamily 36 315 2.9E-8 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK77_RS12850 49be78109ce97fcf8ca94d7cc049f0db 379 SUPERFAMILY SSF103473 10 372 4.97E-19 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK77_RS12850 49be78109ce97fcf8ca94d7cc049f0db 379 Gene3D G3DSA:1.20.1250.20 21 178 3.4E-5 T 06-07-2017 CAK77_RS17815 0ce645188d4870c85326ae80a333241f 223 SUPERFAMILY SSF69754 22 131 2.49E-21 T 06-07-2017 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CAK77_RS17815 0ce645188d4870c85326ae80a333241f 223 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 21 124 2.6E-28 T 06-07-2017 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CAK77_RS17815 0ce645188d4870c85326ae80a333241f 223 Gene3D G3DSA:3.30.160.100 21 120 2.5E-24 T 06-07-2017 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CAK77_RS17815 0ce645188d4870c85326ae80a333241f 223 Pfam PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus 165 218 4.4E-24 T 06-07-2017 IPR032528 Sigma 54 modulation/S30EA ribosomal protein, C-terminal CAK77_RS17815 0ce645188d4870c85326ae80a333241f 223 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 22 118 1.4E-17 T 06-07-2017 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CAK77_RS13320 336587165ff71fda52ca4aa847d1572e 141 Pfam PF01957 NfeD-like C-terminal, partner-binding 4 140 4.9E-23 T 06-07-2017 IPR002810 NfeD-like, C-terminal domain CAK77_RS13320 336587165ff71fda52ca4aa847d1572e 141 SUPERFAMILY SSF141322 79 141 2.22E-9 T 06-07-2017 CAK77_RS13320 336587165ff71fda52ca4aa847d1572e 141 Gene3D G3DSA:2.40.50.140 80 140 9.8E-23 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS19445 f0f795355e03974fd7c46e3b00f285c8 139 Hamap MF_00422 Protein translocase subunit SecE [secE]. 78 136 11.593 T 06-07-2017 IPR022943 Preprotein translocase subunit SecE Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CAK77_RS19445 f0f795355e03974fd7c46e3b00f285c8 139 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 86 139 1.1E-18 T 06-07-2017 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 CAK77_RS19445 f0f795355e03974fd7c46e3b00f285c8 139 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 86 136 5.3E-17 T 06-07-2017 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CAK77_RS19445 f0f795355e03974fd7c46e3b00f285c8 139 ProSitePatterns PS01067 Protein secE/sec61-gamma signature. 86 114 - T 06-07-2017 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CAK77_RS19445 f0f795355e03974fd7c46e3b00f285c8 139 Gene3D G3DSA:1.20.5.1030 82 138 1.7E-19 T 06-07-2017 CAK77_RS16480 551f6d66a3f1391e89b21a2b426915a3 393 Pfam PF00067 Cytochrome P450 272 365 3.2E-15 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS16480 551f6d66a3f1391e89b21a2b426915a3 393 Gene3D G3DSA:1.10.630.10 9 392 2.9E-83 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS16480 551f6d66a3f1391e89b21a2b426915a3 393 SUPERFAMILY SSF48264 11 391 1.83E-65 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS16480 551f6d66a3f1391e89b21a2b426915a3 393 PRINTS PR00359 B-class P450 signature 87 98 2.9E-36 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS16480 551f6d66a3f1391e89b21a2b426915a3 393 PRINTS PR00359 B-class P450 signature 271 282 2.9E-36 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS16480 551f6d66a3f1391e89b21a2b426915a3 393 PRINTS PR00359 B-class P450 signature 288 315 2.9E-36 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS16480 551f6d66a3f1391e89b21a2b426915a3 393 PRINTS PR00359 B-class P450 signature 316 331 2.9E-36 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS16480 551f6d66a3f1391e89b21a2b426915a3 393 PRINTS PR00359 B-class P450 signature 336 345 2.9E-36 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS16480 551f6d66a3f1391e89b21a2b426915a3 393 PRINTS PR00359 B-class P450 signature 133 149 2.9E-36 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS16480 551f6d66a3f1391e89b21a2b426915a3 393 PRINTS PR00359 B-class P450 signature 193 215 2.9E-36 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS16480 551f6d66a3f1391e89b21a2b426915a3 393 PRINTS PR00359 B-class P450 signature 345 356 2.9E-36 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAK77_RS16480 551f6d66a3f1391e89b21a2b426915a3 393 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 338 347 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CAK77_RS16480 551f6d66a3f1391e89b21a2b426915a3 393 PRINTS PR00385 P450 superfamily signature 235 252 1.2E-6 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS16480 551f6d66a3f1391e89b21a2b426915a3 393 PRINTS PR00385 P450 superfamily signature 271 282 1.2E-6 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS16480 551f6d66a3f1391e89b21a2b426915a3 393 PRINTS PR00385 P450 superfamily signature 336 345 1.2E-6 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS16480 551f6d66a3f1391e89b21a2b426915a3 393 PRINTS PR00385 P450 superfamily signature 345 356 1.2E-6 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS15405 0811b042e15f8c693edd08041216e9e6 153 Gene3D G3DSA:1.25.40.10 110 149 1.3E-4 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK77_RS11740 c524ce33171c75a20fef8c654a8ca88d 136 Gene3D G3DSA:3.10.129.10 4 135 1.2E-39 T 06-07-2017 IPR029069 HotDog domain CAK77_RS11740 c524ce33171c75a20fef8c654a8ca88d 136 SUPERFAMILY SSF54637 9 131 4.92E-27 T 06-07-2017 IPR029069 HotDog domain CAK77_RS11740 c524ce33171c75a20fef8c654a8ca88d 136 Pfam PF03061 Thioesterase superfamily 46 127 4.0E-13 T 06-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 CAK77_RS11740 c524ce33171c75a20fef8c654a8ca88d 136 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 19 130 5.3E-20 T 06-07-2017 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-75105 CAK77_RS15890 33155ce3f56a0dbb898cda12d217ce87 197 Pfam PF13977 Bacterial transcriptional repressor 94 191 2.1E-9 T 06-07-2017 CAK77_RS15890 33155ce3f56a0dbb898cda12d217ce87 197 SUPERFAMILY SSF46689 9 87 7.98E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS15890 33155ce3f56a0dbb898cda12d217ce87 197 SUPERFAMILY SSF48498 100 197 1.62E-17 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS15890 33155ce3f56a0dbb898cda12d217ce87 197 Gene3D G3DSA:1.10.357.10 13 197 6.4E-33 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS15890 33155ce3f56a0dbb898cda12d217ce87 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 66 6.5E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS06190 52e78a9730b5fd1943595ae15e781f9e 132 Pfam PF12680 SnoaL-like domain 6 105 2.8E-8 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain CAK77_RS06190 52e78a9730b5fd1943595ae15e781f9e 132 SUPERFAMILY SSF54427 4 123 2.7E-17 T 06-07-2017 IPR032710 NTF2-like domain CAK77_RS06190 52e78a9730b5fd1943595ae15e781f9e 132 Gene3D G3DSA:3.10.450.50 3 114 8.6E-15 T 06-07-2017 IPR032710 NTF2-like domain CAK77_RS05220 782db05ae6f205f9d3ed7dbe77678615 217 SUPERFAMILY SSF46689 9 83 3.15E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS05220 782db05ae6f205f9d3ed7dbe77678615 217 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 67 5.3E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS05220 782db05ae6f205f9d3ed7dbe77678615 217 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 35 1.0E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS05220 782db05ae6f205f9d3ed7dbe77678615 217 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 66 1.0E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS05220 782db05ae6f205f9d3ed7dbe77678615 217 Gene3D G3DSA:1.10.357.10 7 190 1.9E-25 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS13720 30c3ada218162850f6ed502cf8c745d2 225 Pfam PF07161 Protein of unknown function (DUF1396) 34 220 9.0E-52 T 06-07-2017 IPR009830 LppX/LprAFG lipoprotein family CAK77_RS13720 30c3ada218162850f6ed502cf8c745d2 225 SUPERFAMILY SSF89392 31 221 2.2E-52 T 06-07-2017 IPR029046 Lipoprotein localisation LolA/LolB/LppX CAK77_RS13720 30c3ada218162850f6ed502cf8c745d2 225 ProDom PD017293 LIPOPROTEIN MEMBRANE PRECURSOR PALMITATE SIGNAL ANTIGEN LPRG LPPX P27 LPRA 50 220 5.0E-30 T 06-07-2017 IPR009830 LppX/LprAFG lipoprotein family CAK77_RS08100 d79f76998e5ffa9e1cbd32ed72f0856e 179 Gene3D G3DSA:3.40.630.30 5 176 1.1E-38 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS08100 d79f76998e5ffa9e1cbd32ed72f0856e 179 Pfam PF13302 Acetyltransferase (GNAT) domain 16 147 6.4E-17 T 06-07-2017 IPR000182 GNAT domain GO:0008080 CAK77_RS08100 d79f76998e5ffa9e1cbd32ed72f0856e 179 SUPERFAMILY SSF55729 7 170 1.06E-27 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS19805 0e4cbab7cf4f1c2fc4c399aed8bb09b9 152 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 4 150 1.6E-20 T 06-07-2017 IPR019587 Polyketide cyclase/dehydrase CAK77_RS19805 0e4cbab7cf4f1c2fc4c399aed8bb09b9 152 Gene3D G3DSA:3.30.530.20 5 150 1.3E-15 T 06-07-2017 IPR023393 START-like domain CAK77_RS19805 0e4cbab7cf4f1c2fc4c399aed8bb09b9 152 SUPERFAMILY SSF55961 2 151 5.9E-26 T 06-07-2017 CAK77_RS01360 7e9c596925711b025c20713196b6efe8 192 SUPERFAMILY SSF159275 9 192 5.49E-53 T 06-07-2017 CAK77_RS01360 7e9c596925711b025c20713196b6efe8 192 Pfam PF06475 Putative glycolipid-binding 12 191 1.4E-54 T 06-07-2017 IPR009467 Putative glycolipid-binding protein CAK77_RS00120 4870bfb5c2c5ac574cb05363201bdd71 86 SUPERFAMILY SSF47413 15 76 2.79E-11 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK77_RS00120 4870bfb5c2c5ac574cb05363201bdd71 86 Gene3D G3DSA:1.10.260.40 12 75 5.2E-18 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK77_RS00120 4870bfb5c2c5ac574cb05363201bdd71 86 Pfam PF13560 Helix-turn-helix domain 17 74 6.8E-10 T 06-07-2017 CAK77_RS00120 4870bfb5c2c5ac574cb05363201bdd71 86 SMART SM00530 20 74 4.9E-6 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAK77_RS02470 4870bfb5c2c5ac574cb05363201bdd71 86 SUPERFAMILY SSF47413 15 76 2.79E-11 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK77_RS02470 4870bfb5c2c5ac574cb05363201bdd71 86 Gene3D G3DSA:1.10.260.40 12 75 5.2E-18 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK77_RS02470 4870bfb5c2c5ac574cb05363201bdd71 86 Pfam PF13560 Helix-turn-helix domain 17 74 6.8E-10 T 06-07-2017 CAK77_RS02470 4870bfb5c2c5ac574cb05363201bdd71 86 SMART SM00530 20 74 4.9E-6 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAK77_RS09905 eab0957e297444a41ed09566845ee745 192 SUPERFAMILY SSF69118 33 175 4.58E-29 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAK77_RS09905 eab0957e297444a41ed09566845ee745 192 Gene3D G3DSA:1.20.1290.10 33 177 3.2E-31 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAK77_RS09905 eab0957e297444a41ed09566845ee745 192 Pfam PF02627 Carboxymuconolactone decarboxylase family 43 123 7.2E-13 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CAK77_RS04560 1c96cb4feacdbd7e9d121f82a7d82f9e 371 Pfam PF00266 Aminotransferase class-V 41 330 1.0E-16 T 06-07-2017 IPR000192 Aminotransferase class V domain CAK77_RS04560 1c96cb4feacdbd7e9d121f82a7d82f9e 371 SUPERFAMILY SSF53383 17 370 1.29E-76 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK77_RS04560 1c96cb4feacdbd7e9d121f82a7d82f9e 371 PIRSF PIRSF000525 1 371 1.4E-79 T 06-07-2017 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 CAK77_RS04560 1c96cb4feacdbd7e9d121f82a7d82f9e 371 Gene3D G3DSA:3.40.640.10 19 252 9.8E-51 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK77_RS04560 1c96cb4feacdbd7e9d121f82a7d82f9e 371 Gene3D G3DSA:3.90.1150.10 253 366 7.8E-8 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK77_RS04560 1c96cb4feacdbd7e9d121f82a7d82f9e 371 TIGRFAM TIGR01366 serC_3: putative phosphoserine aminotransferase 12 371 3.3E-204 T 06-07-2017 IPR006272 Phosphoserine aminotransferase, Mycobacterial-type GO:0004648|GO:0006564|GO:0009058 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52 CAK77_RS04560 1c96cb4feacdbd7e9d121f82a7d82f9e 371 Hamap MF_00160 Phosphoserine aminotransferase [serC]. 5 371 24.659 T 06-07-2017 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 CAK77_RS12290 0d0ffab5c0f9312170c3a48f4639a4e7 207 Pfam PF08310 LGFP repeat 117 158 2.1E-9 T 06-07-2017 IPR013207 LGFP CAK77_RS12290 0d0ffab5c0f9312170c3a48f4639a4e7 207 Pfam PF08310 LGFP repeat 160 198 1.3E-4 T 06-07-2017 IPR013207 LGFP CAK77_RS22785 de3246e54b162867eaaead997282852d 109 Pfam PF12769 4TM region of pyridine nucleotide transhydrogenase, mitoch 9 94 3.4E-32 T 06-07-2017 IPR024605 NAD(P) transhydrogenase, alpha subunit, C-terminal KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 CAK77_RS06055 4e181bb879c85d93378f110f0b54504b 124 SUPERFAMILY SSF54427 4 118 7.24E-23 T 06-07-2017 IPR032710 NTF2-like domain CAK77_RS06055 4e181bb879c85d93378f110f0b54504b 124 Gene3D G3DSA:3.10.450.50 2 120 7.7E-27 T 06-07-2017 IPR032710 NTF2-like domain CAK77_RS06055 4e181bb879c85d93378f110f0b54504b 124 Pfam PF12680 SnoaL-like domain 12 111 3.9E-15 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain CAK77_RS21885 641577f5a597c225ba301fd5ed1ed2f7 198 Pfam PF01810 LysE type translocator 13 197 3.1E-42 T 06-07-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 CAK77_RS12005 42334b3100641a1dafb758ab851dea10 152 Pfam PF01475 Ferric uptake regulator family 15 105 5.4E-18 T 06-07-2017 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 CAK77_RS12005 42334b3100641a1dafb758ab851dea10 152 SUPERFAMILY SSF46785 7 137 1.36E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS12005 42334b3100641a1dafb758ab851dea10 152 Gene3D G3DSA:1.10.10.10 6 83 5.6E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS22770 cdfce8fee39fb4294ae1b3c0d75838d6 395 Pfam PF06772 Bacterial low temperature requirement A protein (LtrA) 21 373 7.2E-84 T 06-07-2017 IPR010640 Low temperature requirement A CAK77_RS21710 449b6d6996bd60f2c15a65812866a7bd 103 Pfam PF06013 Proteins of 100 residues with WXG 4 87 9.9E-7 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like CAK77_RS21710 449b6d6996bd60f2c15a65812866a7bd 103 Gene3D G3DSA:1.10.287.1060 4 91 9.6E-6 T 06-07-2017 CAK77_RS21710 449b6d6996bd60f2c15a65812866a7bd 103 SUPERFAMILY SSF140453 3 91 2.75E-10 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like CAK77_RS10310 523352498cf91b7aa7ba3a645d266fed 254 SUPERFAMILY SSF53474 14 243 5.8E-39 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS10310 523352498cf91b7aa7ba3a645d266fed 254 Pfam PF00975 Thioesterase domain 22 240 1.5E-37 T 06-07-2017 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 CAK77_RS10310 523352498cf91b7aa7ba3a645d266fed 254 Gene3D G3DSA:3.40.50.1820 10 128 2.7E-25 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS10310 523352498cf91b7aa7ba3a645d266fed 254 Gene3D G3DSA:3.40.50.1820 180 242 2.7E-25 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS20595 566a00cce1ec0c20abd89f46217bf2c2 230 Pfam PF13578 Methyltransferase domain 44 144 2.9E-9 T 06-07-2017 CAK77_RS20595 566a00cce1ec0c20abd89f46217bf2c2 230 Gene3D G3DSA:3.40.50.150 37 161 4.0E-11 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS20595 566a00cce1ec0c20abd89f46217bf2c2 230 SUPERFAMILY SSF53335 24 178 1.3E-30 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS06835 b1fe54ea85ba16a92117105219a0c848 136 Pfam PF02416 mttA/Hcf106 family 5 39 1.4E-4 T 06-07-2017 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 CAK77_RS06835 b1fe54ea85ba16a92117105219a0c848 136 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 2 22 1.0E-10 T 06-07-2017 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 CAK77_RS06835 b1fe54ea85ba16a92117105219a0c848 136 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 22 41 1.0E-10 T 06-07-2017 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 CAK77_RS06835 b1fe54ea85ba16a92117105219a0c848 136 Hamap MF_00237 Sec-independent protein translocase protein TatB [tatB]. 2 134 15.138 T 06-07-2017 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 CAK77_RS06835 b1fe54ea85ba16a92117105219a0c848 136 TIGRFAM TIGR01410 tatB: twin arginine-targeting protein translocase TatB 5 83 3.4E-23 T 06-07-2017 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 CAK77_RS24250 d9621172ec5479edf60d4203849ea49b 451 Gene3D G3DSA:1.20.1250.20 51 204 3.5E-12 T 06-07-2017 CAK77_RS24250 d9621172ec5479edf60d4203849ea49b 451 Pfam PF07690 Major Facilitator Superfamily 61 371 1.5E-9 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK77_RS24250 d9621172ec5479edf60d4203849ea49b 451 SUPERFAMILY SSF103473 23 415 2.09E-18 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK77_RS22010 81a07139d711dcb2c32397fd512cea41 254 PIRSF PIRSF015736 4 246 2.7E-58 T 06-07-2017 IPR026286 Maleate isomerase/Arylmalonate decarboxylase CAK77_RS00320 e8fd95c4fb6482cc07828e3319f9cb86 224 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 3 189 1.2E-61 T 06-07-2017 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CAK77_RS00320 e8fd95c4fb6482cc07828e3319f9cb86 224 PRINTS PR00096 Glutamine amidotransferase superfamily signature 78 89 3.5E-14 T 06-07-2017 CAK77_RS00320 e8fd95c4fb6482cc07828e3319f9cb86 224 PRINTS PR00096 Glutamine amidotransferase superfamily signature 50 59 3.5E-14 T 06-07-2017 CAK77_RS00320 e8fd95c4fb6482cc07828e3319f9cb86 224 PRINTS PR00096 Glutamine amidotransferase superfamily signature 168 181 3.5E-14 T 06-07-2017 CAK77_RS00320 e8fd95c4fb6482cc07828e3319f9cb86 224 Gene3D G3DSA:3.40.50.880 2 192 4.7E-64 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAK77_RS00320 e8fd95c4fb6482cc07828e3319f9cb86 224 Pfam PF00117 Glutamine amidotransferase class-I 5 189 3.6E-52 T 06-07-2017 IPR017926 Glutamine amidotransferase CAK77_RS00320 e8fd95c4fb6482cc07828e3319f9cb86 224 PRINTS PR00097 Anthranilate synthase component II signature 168 181 8.3E-36 T 06-07-2017 CAK77_RS00320 e8fd95c4fb6482cc07828e3319f9cb86 224 PRINTS PR00097 Anthranilate synthase component II signature 3 17 8.3E-36 T 06-07-2017 CAK77_RS00320 e8fd95c4fb6482cc07828e3319f9cb86 224 PRINTS PR00097 Anthranilate synthase component II signature 103 111 8.3E-36 T 06-07-2017 CAK77_RS00320 e8fd95c4fb6482cc07828e3319f9cb86 224 PRINTS PR00097 Anthranilate synthase component II signature 50 59 8.3E-36 T 06-07-2017 CAK77_RS00320 e8fd95c4fb6482cc07828e3319f9cb86 224 PRINTS PR00097 Anthranilate synthase component II signature 78 89 8.3E-36 T 06-07-2017 CAK77_RS00320 e8fd95c4fb6482cc07828e3319f9cb86 224 PRINTS PR00097 Anthranilate synthase component II signature 123 135 8.3E-36 T 06-07-2017 CAK77_RS00320 e8fd95c4fb6482cc07828e3319f9cb86 224 SUPERFAMILY SSF52317 2 192 1.38E-54 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAK77_RS00320 e8fd95c4fb6482cc07828e3319f9cb86 224 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 78 94 8.1E-10 T 06-07-2017 CAK77_RS00320 e8fd95c4fb6482cc07828e3319f9cb86 224 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 47 61 8.1E-10 T 06-07-2017 CAK77_RS09955 0271fea71cf8ef980c69059be1b9c6ab 334 SMART SM00342 248 330 1.1E-19 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK77_RS09955 0271fea71cf8ef980c69059be1b9c6ab 334 SUPERFAMILY SSF46689 286 332 5.38E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS09955 0271fea71cf8ef980c69059be1b9c6ab 334 Pfam PF12833 Helix-turn-helix domain 255 331 2.8E-18 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK77_RS09955 0271fea71cf8ef980c69059be1b9c6ab 334 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 299 314 2.5E-5 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CAK77_RS09955 0271fea71cf8ef980c69059be1b9c6ab 334 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 314 330 2.5E-5 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CAK77_RS09955 0271fea71cf8ef980c69059be1b9c6ab 334 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 69 204 2.1E-11 T 06-07-2017 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal CAK77_RS09955 0271fea71cf8ef980c69059be1b9c6ab 334 Gene3D G3DSA:1.10.10.60 286 332 5.2E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS22015 ebe12456e36431606ac220b47cd7c0a0 314 Gene3D G3DSA:3.40.50.720 36 114 6.7E-8 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS22015 ebe12456e36431606ac220b47cd7c0a0 314 Gene3D G3DSA:3.40.50.720 115 274 1.1E-47 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS22015 ebe12456e36431606ac220b47cd7c0a0 314 SUPERFAMILY SSF52283 40 126 2.98E-8 T 06-07-2017 CAK77_RS22015 ebe12456e36431606ac220b47cd7c0a0 314 SUPERFAMILY SSF51735 106 274 1.9E-44 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS22015 ebe12456e36431606ac220b47cd7c0a0 314 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 112 273 1.2E-41 T 06-07-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CAK77_RS22015 ebe12456e36431606ac220b47cd7c0a0 314 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 37 305 2.1E-6 T 06-07-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CAK77_RS05850 de834403d5accd85cebec4e605e3319a 457 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 85 139 1.9E-7 T 06-07-2017 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CAK77_RS05850 de834403d5accd85cebec4e605e3319a 457 Pfam PF00589 Phage integrase family 254 426 1.6E-11 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAK77_RS05850 de834403d5accd85cebec4e605e3319a 457 SUPERFAMILY SSF56349 84 435 1.28E-47 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CAK77_RS05850 de834403d5accd85cebec4e605e3319a 457 Gene3D G3DSA:1.10.443.10 212 435 1.3E-31 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAK77_RS05850 de834403d5accd85cebec4e605e3319a 457 Gene3D G3DSA:1.10.150.130 84 198 9.6E-13 T 06-07-2017 IPR023109 Integrase/recombinase, N-terminal CAK77_RS08340 844f9a78d01b09f63aa26922ef8aa625 555 Pfam PF14403 Circularly permuted ATP-grasp type 2 104 480 2.9E-161 T 06-07-2017 IPR025841 Circularly permuted ATP-grasp type 2 CAK77_RS08340 844f9a78d01b09f63aa26922ef8aa625 555 PIRSF PIRSF005522 29 507 9.5E-218 T 06-07-2017 IPR016450 Uncharacterised conserved protein UCP005522 CAK77_RS08340 844f9a78d01b09f63aa26922ef8aa625 555 SUPERFAMILY SSF56059 70 242 5.42E-56 T 06-07-2017 CAK77_RS08340 844f9a78d01b09f63aa26922ef8aa625 555 SUPERFAMILY SSF56059 349 495 5.42E-56 T 06-07-2017 CAK77_RS11780 7a090cbcffea290d39166cc38fd0917c 214 Pfam PF01730 UreF 40 167 2.2E-13 T 06-07-2017 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 CAK77_RS11780 7a090cbcffea290d39166cc38fd0917c 214 PIRSF PIRSF009467 3 214 4.1E-36 T 06-07-2017 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 CAK77_RS08080 5684bd166eb968677be7994de12424e9 197 Pfam PF00574 Clp protease 12 186 2.8E-75 T 06-07-2017 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA CAK77_RS08080 5684bd166eb968677be7994de12424e9 197 PRINTS PR00127 Clp protease catalytic subunit P signature 162 181 7.1E-47 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CAK77_RS08080 5684bd166eb968677be7994de12424e9 197 PRINTS PR00127 Clp protease catalytic subunit P signature 53 73 7.1E-47 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CAK77_RS08080 5684bd166eb968677be7994de12424e9 197 PRINTS PR00127 Clp protease catalytic subunit P signature 84 101 7.1E-47 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CAK77_RS08080 5684bd166eb968677be7994de12424e9 197 PRINTS PR00127 Clp protease catalytic subunit P signature 13 28 7.1E-47 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CAK77_RS08080 5684bd166eb968677be7994de12424e9 197 PRINTS PR00127 Clp protease catalytic subunit P signature 105 124 7.1E-47 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CAK77_RS08080 5684bd166eb968677be7994de12424e9 197 Gene3D G3DSA:3.90.226.10 13 186 1.5E-74 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS08080 5684bd166eb968677be7994de12424e9 197 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 106 119 - T 06-07-2017 IPR033135 ClpP, histidine active site CAK77_RS08080 5684bd166eb968677be7994de12424e9 197 SUPERFAMILY SSF52096 13 186 1.65E-63 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS08080 5684bd166eb968677be7994de12424e9 197 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 1 187 37.906 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CAK77_RS08635 54e3822be5ac449faa9524f2648c87f9 272 Pfam PF02405 Permease MlaE 56 259 1.5E-52 T 06-07-2017 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 CAK77_RS07520 aee00d49742c62fa9539c9ca4ef42a36 190 Gene3D G3DSA:1.10.357.10 5 185 1.0E-20 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS07520 aee00d49742c62fa9539c9ca4ef42a36 190 SUPERFAMILY SSF46689 5 68 6.67E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS07520 aee00d49742c62fa9539c9ca4ef42a36 190 SUPERFAMILY SSF48498 72 185 5.34E-21 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS07520 aee00d49742c62fa9539c9ca4ef42a36 190 Pfam PF00440 Bacterial regulatory proteins, tetR family 10 54 1.4E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS04815 e4cbfb6e45e75ad9b5371dc6905c3fe9 142 SMART SM00347 26 126 2.2E-22 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK77_RS04815 e4cbfb6e45e75ad9b5371dc6905c3fe9 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 50 66 1.7E-7 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK77_RS04815 e4cbfb6e45e75ad9b5371dc6905c3fe9 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 67 82 1.7E-7 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK77_RS04815 e4cbfb6e45e75ad9b5371dc6905c3fe9 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 116 136 1.7E-7 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK77_RS04815 e4cbfb6e45e75ad9b5371dc6905c3fe9 142 Gene3D G3DSA:1.10.10.10 8 136 8.5E-32 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS04815 e4cbfb6e45e75ad9b5371dc6905c3fe9 142 SUPERFAMILY SSF46785 8 136 1.81E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS04815 e4cbfb6e45e75ad9b5371dc6905c3fe9 142 Pfam PF01047 MarR family 33 90 1.1E-12 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK77_RS13770 74f9a2bb9b56f90e20a9f86766e03826 339 Pfam PF00296 Luciferase-like monooxygenase 12 305 3.4E-59 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS13770 74f9a2bb9b56f90e20a9f86766e03826 339 Gene3D G3DSA:3.20.20.30 1 330 8.7E-71 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS13770 74f9a2bb9b56f90e20a9f86766e03826 339 SUPERFAMILY SSF51679 1 328 2.22E-61 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS13770 74f9a2bb9b56f90e20a9f86766e03826 339 TIGRFAM TIGR03842 F420_CPS_4043: F420-dependent oxidoreductase, CPS_4043 family 2 330 4.9E-177 T 06-07-2017 IPR022315 F420-dependent oxidoreductase-predicted, CPS4043 CAK77_RS09985 808ada96e6e3f8d20571c82699dc2807 141 SUPERFAMILY SSF54637 10 140 1.43E-28 T 06-07-2017 IPR029069 HotDog domain CAK77_RS09985 808ada96e6e3f8d20571c82699dc2807 141 Pfam PF01575 MaoC like domain 12 113 9.6E-18 T 06-07-2017 IPR002539 MaoC-like domain CAK77_RS09985 808ada96e6e3f8d20571c82699dc2807 141 Gene3D G3DSA:3.10.129.10 5 138 8.6E-29 T 06-07-2017 IPR029069 HotDog domain CAK77_RS17675 15f55d67c523495c0367818f73b41881 243 Pfam PF05423 Mycobacterium membrane protein 150 225 4.5E-6 T 06-07-2017 IPR008693 Transport accessory protein MmpS CAK77_RS23970 5466b2a18caf0efea4d544c47108fd9a 285 Pfam PF00892 EamA-like transporter family 151 284 7.8E-9 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAK77_RS23970 5466b2a18caf0efea4d544c47108fd9a 285 Pfam PF00892 EamA-like transporter family 7 136 3.9E-8 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAK77_RS23970 5466b2a18caf0efea4d544c47108fd9a 285 SUPERFAMILY SSF103481 187 284 5.23E-12 T 06-07-2017 CAK77_RS23970 5466b2a18caf0efea4d544c47108fd9a 285 SUPERFAMILY SSF103481 42 141 2.48E-11 T 06-07-2017 CAK77_RS00340 6cc97717ef7eca2f809fda36bf988214 485 Pfam PF01098 Cell cycle protein 91 458 1.7E-96 T 06-07-2017 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 CAK77_RS07150 2f66c7e661c1591317a6fcaff3f4db52 446 SUPERFAMILY SSF48264 23 446 8.91E-84 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS07150 2f66c7e661c1591317a6fcaff3f4db52 446 PRINTS PR00463 E-class P450 group I signature 352 376 4.8E-27 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS07150 2f66c7e661c1591317a6fcaff3f4db52 446 PRINTS PR00463 E-class P450 group I signature 383 393 4.8E-27 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS07150 2f66c7e661c1591317a6fcaff3f4db52 446 PRINTS PR00463 E-class P450 group I signature 393 416 4.8E-27 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS07150 2f66c7e661c1591317a6fcaff3f4db52 446 PRINTS PR00463 E-class P450 group I signature 261 278 4.8E-27 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS07150 2f66c7e661c1591317a6fcaff3f4db52 446 PRINTS PR00463 E-class P450 group I signature 49 68 4.8E-27 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS07150 2f66c7e661c1591317a6fcaff3f4db52 446 PRINTS PR00463 E-class P450 group I signature 281 307 4.8E-27 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS07150 2f66c7e661c1591317a6fcaff3f4db52 446 PRINTS PR00463 E-class P450 group I signature 311 329 4.8E-27 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS07150 2f66c7e661c1591317a6fcaff3f4db52 446 Pfam PF00067 Cytochrome P450 45 431 7.2E-61 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS07150 2f66c7e661c1591317a6fcaff3f4db52 446 Gene3D G3DSA:1.10.630.10 19 446 1.8E-86 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS07150 2f66c7e661c1591317a6fcaff3f4db52 446 PRINTS PR00385 P450 superfamily signature 272 289 1.5E-11 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS07150 2f66c7e661c1591317a6fcaff3f4db52 446 PRINTS PR00385 P450 superfamily signature 393 404 1.5E-11 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS07150 2f66c7e661c1591317a6fcaff3f4db52 446 PRINTS PR00385 P450 superfamily signature 384 393 1.5E-11 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS07150 2f66c7e661c1591317a6fcaff3f4db52 446 PRINTS PR00385 P450 superfamily signature 312 323 1.5E-11 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS11265 bd66905a79ae1af680d418ef62d15b24 984 Gene3D G3DSA:3.40.50.300 622 683 3.5E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS11265 bd66905a79ae1af680d418ef62d15b24 984 Gene3D G3DSA:3.40.50.300 831 948 3.5E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS11265 bd66905a79ae1af680d418ef62d15b24 984 Gene3D G3DSA:3.40.50.300 6 90 6.2E-54 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS11265 bd66905a79ae1af680d418ef62d15b24 984 Gene3D G3DSA:3.40.50.300 489 607 6.2E-54 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS11265 bd66905a79ae1af680d418ef62d15b24 984 Gene3D G3DSA:3.30.1490.20 131 154 5.1E-26 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CAK77_RS11265 bd66905a79ae1af680d418ef62d15b24 984 Gene3D G3DSA:3.30.1490.20 201 242 5.1E-26 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CAK77_RS11265 bd66905a79ae1af680d418ef62d15b24 984 Gene3D G3DSA:1.10.8.280 291 412 1.2E-40 T 06-07-2017 CAK77_RS11265 bd66905a79ae1af680d418ef62d15b24 984 Pfam PF00005 ABC transporter 634 870 6.6E-10 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK77_RS11265 bd66905a79ae1af680d418ef62d15b24 984 Gene3D G3DSA:1.20.1580.10 92 130 2.9E-49 T 06-07-2017 CAK77_RS11265 bd66905a79ae1af680d418ef62d15b24 984 Gene3D G3DSA:1.20.1580.10 255 289 2.9E-49 T 06-07-2017 CAK77_RS11265 bd66905a79ae1af680d418ef62d15b24 984 Gene3D G3DSA:1.20.1580.10 413 488 2.9E-49 T 06-07-2017 CAK77_RS11265 bd66905a79ae1af680d418ef62d15b24 984 SUPERFAMILY SSF52540 625 924 9.58E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS11265 bd66905a79ae1af680d418ef62d15b24 984 ProSitePatterns PS00211 ABC transporters family signature. 840 854 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK77_RS11265 bd66905a79ae1af680d418ef62d15b24 984 ProSitePatterns PS00211 ABC transporters family signature. 498 512 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK77_RS11265 bd66905a79ae1af680d418ef62d15b24 984 Gene3D G3DSA:1.20.1580.10 704 830 1.5E-55 T 06-07-2017 CAK77_RS11265 bd66905a79ae1af680d418ef62d15b24 984 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 5 935 0.0 T 06-07-2017 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 CAK77_RS11265 bd66905a79ae1af680d418ef62d15b24 984 SUPERFAMILY SSF52540 441 580 1.16E-42 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS11265 bd66905a79ae1af680d418ef62d15b24 984 SUPERFAMILY SSF52540 10 205 1.16E-42 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS11265 bd66905a79ae1af680d418ef62d15b24 984 Hamap MF_00205 UvrABC system protein A [uvrA]. 2 950 22.787 T 06-07-2017 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 CAK77_RS07125 c98831a31d3aae436910c5a265f9d37a 405 Gene3D G3DSA:1.20.140.10 216 400 1.3E-45 T 06-07-2017 CAK77_RS07125 c98831a31d3aae436910c5a265f9d37a 405 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 244 380 5.8E-12 T 06-07-2017 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain CAK77_RS07125 c98831a31d3aae436910c5a265f9d37a 405 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 142 214 3.3E-8 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAK77_RS07125 c98831a31d3aae436910c5a265f9d37a 405 Gene3D G3DSA:2.40.110.10 137 215 1.6E-20 T 06-07-2017 CAK77_RS07125 c98831a31d3aae436910c5a265f9d37a 405 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 18 96 4.7E-5 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS07125 c98831a31d3aae436910c5a265f9d37a 405 Gene3D G3DSA:1.10.540.10 17 107 2.6E-16 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS07125 c98831a31d3aae436910c5a265f9d37a 405 SUPERFAMILY SSF56645 21 224 4.19E-40 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK77_RS07125 c98831a31d3aae436910c5a265f9d37a 405 SUPERFAMILY SSF47203 237 389 6.77E-15 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAK77_RS07125 c98831a31d3aae436910c5a265f9d37a 405 PIRSF PIRSF016578 3 401 8.0E-28 T 06-07-2017 CAK77_RS04490 e29d41281d44ce94ebe0977aa6ecde59 158 Pfam PF05481 Mycobacterium 19 kDa lipoprotein antigen 6 157 4.9E-51 T 06-07-2017 IPR008691 19kDa lipoprotein antigen GO:0016020 CAK77_RS18070 8ccbabe0a32703e467ee4fd46079e19a 576 Gene3D G3DSA:3.90.950.10 14 213 3.8E-54 T 06-07-2017 IPR029001 Inosine triphosphate pyrophosphatase-like CAK77_RS18070 8ccbabe0a32703e467ee4fd46079e19a 576 SUPERFAMILY SSF52972 14 209 6.08E-45 T 06-07-2017 IPR029001 Inosine triphosphate pyrophosphatase-like CAK77_RS18070 8ccbabe0a32703e467ee4fd46079e19a 576 TIGRFAM TIGR00172 maf: septum formation protein Maf 13 207 7.4E-42 T 06-07-2017 IPR003697 Maf-like protein GO:0005737 CAK77_RS18070 8ccbabe0a32703e467ee4fd46079e19a 576 Hamap MF_00528 Septum formation protein Maf [maf]. 14 214 27.291 T 06-07-2017 IPR003697 Maf-like protein GO:0005737 CAK77_RS18070 8ccbabe0a32703e467ee4fd46079e19a 576 Pfam PF02545 Maf-like protein 15 209 2.3E-41 T 06-07-2017 IPR003697 Maf-like protein GO:0005737 CAK77_RS19340 816daf9abf47d66b990827a6e5ca6838 250 Pfam PF00440 Bacterial regulatory proteins, tetR family 36 82 2.5E-13 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS19340 816daf9abf47d66b990827a6e5ca6838 250 Gene3D G3DSA:1.10.357.10 34 221 5.7E-38 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS19340 816daf9abf47d66b990827a6e5ca6838 250 SUPERFAMILY SSF46689 33 96 3.03E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS19340 816daf9abf47d66b990827a6e5ca6838 250 SUPERFAMILY SSF48498 106 225 1.98E-21 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS19340 816daf9abf47d66b990827a6e5ca6838 250 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 57 80 5.1E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS19340 816daf9abf47d66b990827a6e5ca6838 250 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 49 5.1E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS19340 816daf9abf47d66b990827a6e5ca6838 250 Pfam PF13305 WHG domain 110 204 4.9E-13 T 06-07-2017 IPR025996 WHG domain CAK77_RS15870 b1bac1834ef0645c03a8bd6906e105be 753 Pfam PF13245 Part of AAA domain 197 258 2.6E-14 T 06-07-2017 CAK77_RS15870 b1bac1834ef0645c03a8bd6906e105be 753 SUPERFAMILY SSF52540 184 262 5.97E-41 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS15870 b1bac1834ef0645c03a8bd6906e105be 753 SUPERFAMILY SSF52540 515 725 5.97E-41 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS15870 b1bac1834ef0645c03a8bd6906e105be 753 Gene3D G3DSA:3.40.50.300 676 730 1.8E-10 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS15870 b1bac1834ef0645c03a8bd6906e105be 753 Gene3D G3DSA:3.40.50.300 507 608 1.6E-30 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS15870 b1bac1834ef0645c03a8bd6906e105be 753 Gene3D G3DSA:3.40.50.300 184 292 1.6E-30 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS07960 91a2c4436c5d322fa61f53ae4a1090d7 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 9 22 3.2E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS07960 91a2c4436c5d322fa61f53ae4a1090d7 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 53 3.2E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS07960 91a2c4436c5d322fa61f53ae4a1090d7 212 SUPERFAMILY SSF48498 80 202 1.2E-6 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS07960 91a2c4436c5d322fa61f53ae4a1090d7 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 55 2.0E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS07960 91a2c4436c5d322fa61f53ae4a1090d7 212 Gene3D G3DSA:1.10.357.10 3 200 2.9E-32 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS07960 91a2c4436c5d322fa61f53ae4a1090d7 212 SUPERFAMILY SSF46689 3 75 9.23E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS09605 b0e22d0a3c7dcd393a96a9844e549741 385 Pfam PF00534 Glycosyl transferases group 1 188 363 5.9E-42 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 CAK77_RS09605 b0e22d0a3c7dcd393a96a9844e549741 385 Pfam PF13439 Glycosyltransferase Family 4 23 180 1.7E-14 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 CAK77_RS09605 b0e22d0a3c7dcd393a96a9844e549741 385 Gene3D G3DSA:3.40.50.2000 172 361 1.9E-38 T 06-07-2017 CAK77_RS09605 b0e22d0a3c7dcd393a96a9844e549741 385 SUPERFAMILY SSF53756 11 380 9.42E-83 T 06-07-2017 CAK77_RS14065 ff259747c440395c9e596bb8cab743c0 289 Gene3D G3DSA:3.40.710.10 33 287 2.2E-92 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK77_RS14065 ff259747c440395c9e596bb8cab743c0 289 Pfam PF13354 Beta-lactamase enzyme family 55 260 3.0E-37 T 06-07-2017 CAK77_RS14065 ff259747c440395c9e596bb8cab743c0 289 SUPERFAMILY SSF56601 33 287 1.37E-67 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK77_RS14065 ff259747c440395c9e596bb8cab743c0 289 PRINTS PR00118 Beta-lactamase class A signature 65 82 8.2E-56 T 06-07-2017 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CAK77_RS14065 ff259747c440395c9e596bb8cab743c0 289 PRINTS PR00118 Beta-lactamase class A signature 203 218 8.2E-56 T 06-07-2017 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CAK77_RS14065 ff259747c440395c9e596bb8cab743c0 289 PRINTS PR00118 Beta-lactamase class A signature 107 132 8.2E-56 T 06-07-2017 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CAK77_RS14065 ff259747c440395c9e596bb8cab743c0 289 PRINTS PR00118 Beta-lactamase class A signature 34 58 8.2E-56 T 06-07-2017 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CAK77_RS14065 ff259747c440395c9e596bb8cab743c0 289 PRINTS PR00118 Beta-lactamase class A signature 143 167 8.2E-56 T 06-07-2017 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CAK77_RS14065 ff259747c440395c9e596bb8cab743c0 289 PRINTS PR00118 Beta-lactamase class A signature 220 235 8.2E-56 T 06-07-2017 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CAK77_RS08355 053563a295f947b891af7d13b557d24d 215 Gene3D G3DSA:1.10.357.10 16 200 5.0E-27 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS08355 053563a295f947b891af7d13b557d24d 215 SUPERFAMILY SSF46689 14 83 2.82E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS08355 053563a295f947b891af7d13b557d24d 215 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 72 4.9E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS10545 9b089895227f3d7bac0de480d93b7b99 234 Gene3D G3DSA:3.30.530.20 69 181 7.9E-7 T 06-07-2017 IPR023393 START-like domain CAK77_RS10545 9b089895227f3d7bac0de480d93b7b99 234 SUPERFAMILY SSF55961 67 219 7.97E-12 T 06-07-2017 CAK77_RS07950 5e0a7dfb833400507fb1f5d3fee355ff 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 53 76 3.0E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS07950 5e0a7dfb833400507fb1f5d3fee355ff 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 45 3.0E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS07950 5e0a7dfb833400507fb1f5d3fee355ff 220 Gene3D G3DSA:1.10.357.10 29 201 5.6E-27 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS07950 5e0a7dfb833400507fb1f5d3fee355ff 220 SUPERFAMILY SSF46689 24 101 8.48E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS07950 5e0a7dfb833400507fb1f5d3fee355ff 220 Pfam PF00440 Bacterial regulatory proteins, tetR family 32 77 9.0E-16 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS19905 261349e909c8a94422591536b668952b 323 Pfam PF01578 Cytochrome C assembly protein 110 317 4.4E-46 T 06-07-2017 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 CAK77_RS19905 261349e909c8a94422591536b668952b 323 TIGRFAM TIGR03144 cytochr_II_ccsB: cytochrome c-type biogenesis protein CcsB 88 320 4.6E-70 T 06-07-2017 IPR017562 Cytochrome c-type biogenesis protein CcsA GO:0017004 CAK77_RS17965 10e3c6e83769a7fa07f5feea24c08f64 359 Gene3D G3DSA:2.160.10.10 253 350 3.1E-17 T 06-07-2017 CAK77_RS17965 10e3c6e83769a7fa07f5feea24c08f64 359 Gene3D G3DSA:3.90.550.10 8 238 2.2E-69 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK77_RS17965 10e3c6e83769a7fa07f5feea24c08f64 359 SUPERFAMILY SSF53448 9 308 6.1E-73 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK77_RS17965 10e3c6e83769a7fa07f5feea24c08f64 359 Pfam PF00483 Nucleotidyl transferase 9 235 1.9E-44 T 06-07-2017 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CAK77_RS17965 10e3c6e83769a7fa07f5feea24c08f64 359 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 255 286 1.7E-4 T 06-07-2017 IPR001451 Hexapeptide repeat CAK77_RS17965 10e3c6e83769a7fa07f5feea24c08f64 359 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 305 336 0.0013 T 06-07-2017 IPR001451 Hexapeptide repeat CAK77_RS08830 8830c9e4f8b2faa3ba1d20ec3a01fd37 250 Pfam PF02265 S1/P1 Nuclease 18 249 8.1E-65 T 06-07-2017 IPR003154 S1/P1 nuclease GO:0003676|GO:0004519|GO:0006308 CAK77_RS08830 8830c9e4f8b2faa3ba1d20ec3a01fd37 250 SUPERFAMILY SSF48537 18 246 2.22E-58 T 06-07-2017 IPR008947 Phospholipase C/P1 nuclease domain GO:0016788 CAK77_RS08830 8830c9e4f8b2faa3ba1d20ec3a01fd37 250 Gene3D G3DSA:1.10.575.10 18 249 5.6E-70 T 06-07-2017 IPR008947 Phospholipase C/P1 nuclease domain GO:0016788 CAK77_RS22435 bf326e193329149c2f2e3f1f4b6e87f0 434 SUPERFAMILY SSF102824 337 427 3.92E-10 T 06-07-2017 CAK77_RS22435 bf326e193329149c2f2e3f1f4b6e87f0 434 Pfam PF11429 Colicin D 339 425 9.3E-13 T 06-07-2017 IPR024440 Colicin D C-terminal GO:0004540 CAK77_RS02380 fefa96a42a0cde663a31a6b052da3201 293 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 35 223 1.1E-23 T 06-07-2017 IPR006383 HAD-superfamily hydrolase, subfamily IB, PSPase-like GO:0008152|GO:0016791 CAK77_RS02380 fefa96a42a0cde663a31a6b052da3201 293 SUPERFAMILY SSF56784 29 240 1.06E-29 T 06-07-2017 IPR023214 HAD-like domain CAK77_RS02380 fefa96a42a0cde663a31a6b052da3201 293 Gene3D G3DSA:3.40.50.1000 107 252 7.7E-49 T 06-07-2017 IPR023214 HAD-like domain CAK77_RS02380 fefa96a42a0cde663a31a6b052da3201 293 Pfam PF12710 haloacid dehalogenase-like hydrolase 36 221 1.6E-31 T 06-07-2017 CAK77_RS02380 fefa96a42a0cde663a31a6b052da3201 293 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 35 234 2.8E-69 T 06-07-2017 IPR006385 HAD-superfamily hydrolase, subfamily IB, PSPase-like, bacterial CAK77_RS00130 685a2fc9ae95cadc588419ff97ef1ac0 398 Gene3D G3DSA:1.10.260.40 9 68 1.2E-5 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK77_RS00130 685a2fc9ae95cadc588419ff97ef1ac0 398 Pfam PF06114 Domain of unknown function (DUF955) 186 280 2.8E-11 T 06-07-2017 IPR010359 HTH domain, IrrE-type CAK77_RS00130 685a2fc9ae95cadc588419ff97ef1ac0 398 SUPERFAMILY SSF47413 3 67 9.5E-5 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK77_RS02460 685a2fc9ae95cadc588419ff97ef1ac0 398 Gene3D G3DSA:1.10.260.40 9 68 1.2E-5 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK77_RS02460 685a2fc9ae95cadc588419ff97ef1ac0 398 Pfam PF06114 Domain of unknown function (DUF955) 186 280 2.8E-11 T 06-07-2017 IPR010359 HTH domain, IrrE-type CAK77_RS02460 685a2fc9ae95cadc588419ff97ef1ac0 398 SUPERFAMILY SSF47413 3 67 9.5E-5 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK77_RS01195 37411acc6207b222b584a10373575455 398 Pfam PF00266 Aminotransferase class-V 21 390 2.1E-31 T 06-07-2017 IPR000192 Aminotransferase class V domain CAK77_RS01195 37411acc6207b222b584a10373575455 398 TIGRFAM TIGR01976 am_tr_V_VC1184: cysteine desulfurase family protein 3 394 7.7E-129 T 06-07-2017 IPR011340 Cysteine desulfurase-related CAK77_RS01195 37411acc6207b222b584a10373575455 398 Gene3D G3DSA:3.90.1150.10 262 396 6.6E-20 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK77_RS01195 37411acc6207b222b584a10373575455 398 SUPERFAMILY SSF53383 3 396 3.3E-60 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK77_RS01195 37411acc6207b222b584a10373575455 398 Gene3D G3DSA:3.40.640.10 34 261 2.6E-38 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK77_RS21630 74772abf74cd8ef5cf4bb278ab5cd352 218 Pfam PF03734 L,D-transpeptidase catalytic domain 57 214 6.2E-8 T 06-07-2017 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 CAK77_RS07935 272385bc3996154c6b8fcb043ca7eb4e 317 Gene3D G3DSA:3.30.2010.10 82 169 5.2E-13 T 06-07-2017 CAK77_RS07935 272385bc3996154c6b8fcb043ca7eb4e 317 Pfam PF01435 Peptidase family M48 95 188 3.7E-17 T 06-07-2017 IPR001915 Peptidase M48 GO:0004222|GO:0006508 CAK77_RS04190 3411bb73b386f442f84b9617bb4784f2 486 Gene3D G3DSA:3.40.309.10 262 452 2.2E-60 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAK77_RS04190 3411bb73b386f442f84b9617bb4784f2 486 SUPERFAMILY SSF53720 4 480 1.96E-148 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAK77_RS04190 3411bb73b386f442f84b9617bb4784f2 486 Gene3D G3DSA:3.40.605.10 4 261 6.8E-85 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAK77_RS04190 3411bb73b386f442f84b9617bb4784f2 486 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 248 255 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CAK77_RS04190 3411bb73b386f442f84b9617bb4784f2 486 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 276 287 - T 06-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CAK77_RS04190 3411bb73b386f442f84b9617bb4784f2 486 Pfam PF00171 Aldehyde dehydrogenase family 20 478 1.4E-149 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAK77_RS08845 00c0758ed184d06c16642a953fca6b58 179 SUPERFAMILY SSF81342 11 177 1.57E-30 T 06-07-2017 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 CAK77_RS08845 00c0758ed184d06c16642a953fca6b58 179 Pfam PF01292 Prokaryotic cytochrome b561 12 177 3.5E-23 T 06-07-2017 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 CAK77_RS08845 00c0758ed184d06c16642a953fca6b58 179 Gene3D G3DSA:1.20.950.20 11 163 7.3E-5 T 06-07-2017 CAK77_RS08765 4f3deac6b7f87fe9a61d5b9443106832 288 SUPERFAMILY SSF161098 51 274 4.45E-54 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS08765 4f3deac6b7f87fe9a61d5b9443106832 288 Gene3D G3DSA:1.10.3720.10 3 276 4.8E-60 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS08765 4f3deac6b7f87fe9a61d5b9443106832 288 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 82 284 1.6E-17 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS00435 f9da62066abbed3d8347a65f15c8fa7a 156 Gene3D G3DSA:3.30.1160.10 89 153 7.6E-35 T 06-07-2017 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAK77_RS00435 f9da62066abbed3d8347a65f15c8fa7a 156 Gene3D G3DSA:1.10.260.40 1 87 8.4E-28 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK77_RS00435 f9da62066abbed3d8347a65f15c8fa7a 156 PIRSF PIRSF001263 3 156 2.8E-56 T 06-07-2017 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAK77_RS00435 f9da62066abbed3d8347a65f15c8fa7a 156 Hamap MF_00535 Cyanate hydratase [cynS]. 1 156 75.028 T 06-07-2017 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAK77_RS00435 f9da62066abbed3d8347a65f15c8fa7a 156 SUPERFAMILY SSF47413 5 85 4.82E-18 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK77_RS00435 f9da62066abbed3d8347a65f15c8fa7a 156 TIGRFAM TIGR00673 cynS: cyanase 14 156 1.3E-53 T 06-07-2017 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAK77_RS00435 f9da62066abbed3d8347a65f15c8fa7a 156 PRINTS PR01693 Cyanase signature 91 105 4.2E-32 T 06-07-2017 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAK77_RS00435 f9da62066abbed3d8347a65f15c8fa7a 156 PRINTS PR01693 Cyanase signature 109 125 4.2E-32 T 06-07-2017 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAK77_RS00435 f9da62066abbed3d8347a65f15c8fa7a 156 PRINTS PR01693 Cyanase signature 141 151 4.2E-32 T 06-07-2017 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAK77_RS00435 f9da62066abbed3d8347a65f15c8fa7a 156 PRINTS PR01693 Cyanase signature 42 59 4.2E-32 T 06-07-2017 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAK77_RS00435 f9da62066abbed3d8347a65f15c8fa7a 156 PRINTS PR01693 Cyanase signature 22 37 4.2E-32 T 06-07-2017 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAK77_RS00435 f9da62066abbed3d8347a65f15c8fa7a 156 SUPERFAMILY SSF55234 88 153 3.01E-28 T 06-07-2017 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAK77_RS00435 f9da62066abbed3d8347a65f15c8fa7a 156 SMART SM01116 83 156 5.2E-44 T 06-07-2017 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAK77_RS00435 f9da62066abbed3d8347a65f15c8fa7a 156 Pfam PF02560 Cyanate lyase C-terminal domain 88 152 9.2E-32 T 06-07-2017 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAK77_RS19730 48ebe98fbf208ceb96a14fb99d70667f 388 SUPERFAMILY SSF55073 214 376 2.35E-29 T 06-07-2017 IPR029787 Nucleotide cyclase CAK77_RS19730 48ebe98fbf208ceb96a14fb99d70667f 388 Gene3D G3DSA:3.30.70.270 211 380 4.7E-37 T 06-07-2017 CAK77_RS19730 48ebe98fbf208ceb96a14fb99d70667f 388 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 208 375 2.9E-31 T 06-07-2017 IPR000160 GGDEF domain CAK77_RS19730 48ebe98fbf208ceb96a14fb99d70667f 388 SMART SM00267 198 377 4.9E-29 T 06-07-2017 IPR000160 GGDEF domain CAK77_RS19730 48ebe98fbf208ceb96a14fb99d70667f 388 Pfam PF00990 Diguanylate cyclase, GGDEF domain 209 372 5.7E-29 T 06-07-2017 IPR000160 GGDEF domain CAK77_RS02270 0d4b8bf92dc8b99893b28839e9d1f810 105 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 86 16.417 T 06-07-2017 IPR003482 Transcription factor WhiB CAK77_RS02270 0d4b8bf92dc8b99893b28839e9d1f810 105 Pfam PF02467 Transcription factor WhiB 19 81 9.7E-21 T 06-07-2017 IPR003482 Transcription factor WhiB CAK77_RS15205 3e79cf278312638b4b43e91004e9094f 150 Pfam PF07080 Protein of unknown function (DUF1348) 3 140 1.8E-68 T 06-07-2017 IPR009783 Protein of unknown function DUF1348 CAK77_RS15205 3e79cf278312638b4b43e91004e9094f 150 SUPERFAMILY SSF54427 2 140 4.5E-70 T 06-07-2017 IPR032710 NTF2-like domain CAK77_RS15205 3e79cf278312638b4b43e91004e9094f 150 Gene3D G3DSA:3.10.450.50 12 139 1.7E-65 T 06-07-2017 IPR032710 NTF2-like domain CAK77_RS13630 aca868e5213f6636b3a3d6fe42cc6ca9 647 Pfam PF01019 Gamma-glutamyltranspeptidase 96 640 6.0E-147 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAK77_RS13630 aca868e5213f6636b3a3d6fe42cc6ca9 647 SUPERFAMILY SSF56235 71 644 3.4E-146 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAK77_RS13630 aca868e5213f6636b3a3d6fe42cc6ca9 647 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 538 555 2.3E-63 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAK77_RS13630 aca868e5213f6636b3a3d6fe42cc6ca9 647 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 103 128 2.3E-63 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAK77_RS13630 aca868e5213f6636b3a3d6fe42cc6ca9 647 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 180 198 2.3E-63 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAK77_RS13630 aca868e5213f6636b3a3d6fe42cc6ca9 647 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 449 467 2.3E-63 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAK77_RS13630 aca868e5213f6636b3a3d6fe42cc6ca9 647 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 471 489 2.3E-63 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAK77_RS13630 aca868e5213f6636b3a3d6fe42cc6ca9 647 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 302 318 2.3E-63 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAK77_RS13630 aca868e5213f6636b3a3d6fe42cc6ca9 647 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 332 351 2.3E-63 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAK77_RS13630 aca868e5213f6636b3a3d6fe42cc6ca9 647 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 198 217 2.3E-63 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAK77_RS13630 aca868e5213f6636b3a3d6fe42cc6ca9 647 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 508 523 2.3E-63 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAK77_RS20130 e27a715d8f76c5a85874ff0b7cfca317 256 Pfam PF08241 Methyltransferase domain 94 190 3.6E-21 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CAK77_RS20130 e27a715d8f76c5a85874ff0b7cfca317 256 Gene3D G3DSA:3.40.50.150 79 236 3.6E-33 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS20130 e27a715d8f76c5a85874ff0b7cfca317 256 SUPERFAMILY SSF53335 77 239 1.07E-34 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS12340 4cb61246f6885bbd8ffd84d312a6cde7 340 Gene3D G3DSA:3.75.10.10 2 338 1.5E-111 T 06-07-2017 CAK77_RS12340 4cb61246f6885bbd8ffd84d312a6cde7 340 Pfam PF04371 Porphyromonas-type peptidyl-arginine deiminase 5 337 4.0E-101 T 06-07-2017 IPR007466 Peptidyl-arginine deiminase, Porphyromonas-type GO:0004668|GO:0009446 KEGG: 00330+3.5.3.12|MetaCyc: PWY-43 CAK77_RS12340 4cb61246f6885bbd8ffd84d312a6cde7 340 SUPERFAMILY SSF55909 1 338 5.18E-111 T 06-07-2017 CAK77_RS12045 465f2c8ca8fb848510c70aff771d37cd 140 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 11 105 1.4E-15 T 06-07-2017 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CAK77_RS12045 465f2c8ca8fb848510c70aff771d37cd 140 SUPERFAMILY SSF55961 2 134 4.72E-28 T 06-07-2017 CAK77_RS12045 465f2c8ca8fb848510c70aff771d37cd 140 Gene3D G3DSA:3.30.530.20 3 138 5.4E-25 T 06-07-2017 IPR023393 START-like domain CAK77_RS19950 6882b4f85536555d8cfa9a79c5d501cf 259 Pfam PF01925 Sulfite exporter TauE/SafE 10 252 1.9E-38 T 06-07-2017 IPR002781 Transmembrane protein TauE-like GO:0016021 CAK77_RS10385 0d72922eade5d270742497f17c85d878 242 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 150 205 5.0E-20 T 06-07-2017 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS10385 0d72922eade5d270742497f17c85d878 242 Hamap MF_01357 NAD(P)H-quinone oxidoreductase subunit J, chloroplastic [ndhJ]. 68 230 27.506 T 06-07-2017 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS10385 0d72922eade5d270742497f17c85d878 242 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 100 222 4.5E-38 T 06-07-2017 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS10385 0d72922eade5d270742497f17c85d878 242 SUPERFAMILY SSF143243 85 238 8.5E-45 T 06-07-2017 CAK77_RS10385 0d72922eade5d270742497f17c85d878 242 TIGRFAM TIGR01961 NuoC_fam: NADH (or F420H2) dehydrogenase, subunit C 99 221 2.3E-43 T 06-07-2017 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS11765 35c95f02f763126364c5cde0a3dbdcb9 100 Hamap MF_00739 Urease subunit gamma [ureA]. 1 100 34.491 T 06-07-2017 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAK77_RS11765 35c95f02f763126364c5cde0a3dbdcb9 100 Gene3D G3DSA:3.30.280.10 1 99 2.2E-48 T 06-07-2017 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAK77_RS11765 35c95f02f763126364c5cde0a3dbdcb9 100 PIRSF PIRSF001223 1 100 1.3E-49 T 06-07-2017 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAK77_RS11765 35c95f02f763126364c5cde0a3dbdcb9 100 Pfam PF00547 Urease, gamma subunit 1 99 1.6E-46 T 06-07-2017 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAK77_RS11765 35c95f02f763126364c5cde0a3dbdcb9 100 ProDom PD002319 SUBUNIT GAMMA HYDROLASE UREASE UREA AMIDOHYDROLASE UREASE ALPHA GAMMA/BETA METAL-BINDING 9 99 1.0E-30 T 06-07-2017 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAK77_RS11765 35c95f02f763126364c5cde0a3dbdcb9 100 TIGRFAM TIGR00193 urease_gam: urease, gamma subunit 1 99 2.4E-47 T 06-07-2017 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAK77_RS11765 35c95f02f763126364c5cde0a3dbdcb9 100 SUPERFAMILY SSF54111 1 99 5.1E-45 T 06-07-2017 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAK77_RS13490 c3d9c97da4d6f68d9f0e3e638066af9d 265 TIGRFAM TIGR00025 Mtu_efflux: ABC transporter efflux protein, DrrB family 38 265 1.5E-51 T 06-07-2017 IPR004377 ABC transporter, permease protein DrrB/DrrC GO:0042891|GO:0043215|GO:0046677|GO:1900753 CAK77_RS13490 c3d9c97da4d6f68d9f0e3e638066af9d 265 Pfam PF01061 ABC-2 type transporter 29 196 1.1E-8 T 06-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CAK77_RS14630 b2e96b5b0bc6327694d3d2f6c1fea6f7 236 SMART SM00895 94 218 2.9E-12 T 06-07-2017 IPR011711 GntR, C-terminal CAK77_RS14630 b2e96b5b0bc6327694d3d2f6c1fea6f7 236 Gene3D G3DSA:1.20.120.530 88 224 2.1E-22 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAK77_RS14630 b2e96b5b0bc6327694d3d2f6c1fea6f7 236 SUPERFAMILY SSF48008 90 225 5.75E-21 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAK77_RS14630 b2e96b5b0bc6327694d3d2f6c1fea6f7 236 SMART SM00345 26 84 1.3E-9 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK77_RS14630 b2e96b5b0bc6327694d3d2f6c1fea6f7 236 Pfam PF00392 Bacterial regulatory proteins, gntR family 25 84 2.7E-12 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK77_RS14630 b2e96b5b0bc6327694d3d2f6c1fea6f7 236 Pfam PF07729 FCD domain 94 215 1.2E-17 T 06-07-2017 IPR011711 GntR, C-terminal CAK77_RS14630 b2e96b5b0bc6327694d3d2f6c1fea6f7 236 SUPERFAMILY SSF46785 24 88 1.36E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS14630 b2e96b5b0bc6327694d3d2f6c1fea6f7 236 Gene3D G3DSA:1.10.10.10 18 85 1.0E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS17510 bcd11cab5185d45586fef94390b5727b 117 TIGRFAM TIGR04529 MTB_hemophore: hemophore-related protein, Rv0203/Rv1174c family 36 111 9.1E-24 T 06-07-2017 IPR032407 Haemophore, haem-binding GO:0020037 CAK77_RS17510 bcd11cab5185d45586fef94390b5727b 117 Pfam PF16525 Haemophore, haem-binding 34 110 2.6E-30 T 06-07-2017 IPR032407 Haemophore, haem-binding GO:0020037 CAK77_RS05595 6ef682bf3d6ba0151b8cd6f13c37c697 291 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 19 276 9.8E-79 T 06-07-2017 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 CAK77_RS05595 6ef682bf3d6ba0151b8cd6f13c37c697 291 Gene3D G3DSA:3.20.20.140 15 277 1.0E-79 T 06-07-2017 CAK77_RS05595 6ef682bf3d6ba0151b8cd6f13c37c697 291 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 19 27 - T 06-07-2017 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 CAK77_RS05595 6ef682bf3d6ba0151b8cd6f13c37c697 291 PIRSF PIRSF005902 14 280 2.7E-69 T 06-07-2017 IPR001130 TatD family GO:0016788 CAK77_RS05595 6ef682bf3d6ba0151b8cd6f13c37c697 291 Pfam PF01026 TatD related DNase 20 276 2.0E-66 T 06-07-2017 IPR001130 TatD family GO:0016788 CAK77_RS05595 6ef682bf3d6ba0151b8cd6f13c37c697 291 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 212 228 - T 06-07-2017 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 CAK77_RS05595 6ef682bf3d6ba0151b8cd6f13c37c697 291 SUPERFAMILY SSF51556 19 277 1.59E-74 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK77_RS09395 1cf49c9e4f712cc0bb813be0bd8fb30d 154 PIRSF PIRSF021697 1 153 6.9E-50 T 06-07-2017 IPR016795 Uncharacterised conserved protein UCP021697, membrane CAK77_RS09395 1cf49c9e4f712cc0bb813be0bd8fb30d 154 Pfam PF06271 RDD family 39 129 1.9E-7 T 06-07-2017 IPR010432 RDD CAK77_RS15825 1962f403ba9d1fea66e1992dcaaf5fb5 318 SUPERFAMILY SSF103481 198 290 5.89E-10 T 06-07-2017 CAK77_RS15825 1962f403ba9d1fea66e1992dcaaf5fb5 318 SUPERFAMILY SSF103481 43 140 2.62E-14 T 06-07-2017 CAK77_RS15825 1962f403ba9d1fea66e1992dcaaf5fb5 318 Pfam PF00892 EamA-like transporter family 13 138 1.5E-12 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAK77_RS15825 1962f403ba9d1fea66e1992dcaaf5fb5 318 Pfam PF00892 EamA-like transporter family 156 285 1.4E-9 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAK77_RS10400 3af6c37256d1829c65acce23a4916e78 434 ProSitePatterns PS00644 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. 168 183 - T 06-07-2017 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS10400 3af6c37256d1829c65acce23a4916e78 434 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 342 353 - T 06-07-2017 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS10400 3af6c37256d1829c65acce23a4916e78 434 SMART SM00928 329 374 3.8E-27 T 06-07-2017 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS10400 3af6c37256d1829c65acce23a4916e78 434 Pfam PF10531 SLBB domain 245 291 3.7E-9 T 06-07-2017 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS10400 3af6c37256d1829c65acce23a4916e78 434 SUPERFAMILY SSF142019 9 240 1.24E-88 T 06-07-2017 CAK77_RS10400 3af6c37256d1829c65acce23a4916e78 434 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 49 220 1.2E-47 T 06-07-2017 IPR011538 NADH-ubiquinone oxidoreductase 51 kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS10400 3af6c37256d1829c65acce23a4916e78 434 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 331 414 9.0E-32 T 06-07-2017 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS10400 3af6c37256d1829c65acce23a4916e78 434 TIGRFAM TIGR01959 nuoF_fam: NADH oxidoreductase (quinone), F subunit 10 414 4.7E-193 T 06-07-2017 IPR011537 NADH ubiquinone oxidoreductase, F subunit GO:0010181|GO:0016651|GO:0051287|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS10400 3af6c37256d1829c65acce23a4916e78 434 SUPERFAMILY SSF140490 325 421 1.1E-37 T 06-07-2017 CAK77_RS10400 3af6c37256d1829c65acce23a4916e78 434 SUPERFAMILY SSF142984 243 324 9.55E-22 T 06-07-2017 CAK77_RS18065 acfb35e10cd3f9557e8ecf65ecf4a932 92 Pfam PF13822 Acyl-CoA carboxylase epsilon subunit 23 74 1.9E-15 T 06-07-2017 IPR032716 Acyl-CoA carboxylase epsilon subunit CAK77_RS21555 891f33d180be279c39d25e7a74a09a44 557 Pfam PF01391 Collagen triple helix repeat (20 copies) 283 334 2.2E-7 T 06-07-2017 IPR008160 Collagen triple helix repeat CAK77_RS03090 abbfd00d850d78712eb1f10d6062133a 530 Gene3D G3DSA:3.40.50.980 11 184 5.8E-35 T 06-07-2017 CAK77_RS03090 abbfd00d850d78712eb1f10d6062133a 530 ProSitePatterns PS00455 Putative AMP-binding domain signature. 180 191 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK77_RS03090 abbfd00d850d78712eb1f10d6062133a 530 Gene3D G3DSA:3.40.50.980 185 349 1.1E-41 T 06-07-2017 CAK77_RS03090 abbfd00d850d78712eb1f10d6062133a 530 Gene3D G3DSA:2.30.38.10 350 418 9.4E-22 T 06-07-2017 CAK77_RS03090 abbfd00d850d78712eb1f10d6062133a 530 SUPERFAMILY SSF56801 8 519 1.11E-141 T 06-07-2017 CAK77_RS03090 abbfd00d850d78712eb1f10d6062133a 530 Gene3D G3DSA:3.30.300.30 424 522 8.7E-27 T 06-07-2017 CAK77_RS03090 abbfd00d850d78712eb1f10d6062133a 530 Pfam PF13193 AMP-binding enzyme C-terminal domain 434 509 1.1E-16 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAK77_RS03090 abbfd00d850d78712eb1f10d6062133a 530 Pfam PF00501 AMP-binding enzyme 17 424 2.8E-96 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK77_RS12155 1e5b6a5aaa83c1d360dd813e8b20d695 173 PRINTS PR01217 Proline rich extensin signature 58 79 1.9E-11 T 06-07-2017 CAK77_RS12155 1e5b6a5aaa83c1d360dd813e8b20d695 173 PRINTS PR01217 Proline rich extensin signature 147 172 1.9E-11 T 06-07-2017 CAK77_RS12155 1e5b6a5aaa83c1d360dd813e8b20d695 173 PRINTS PR01217 Proline rich extensin signature 112 129 1.9E-11 T 06-07-2017 CAK77_RS12155 1e5b6a5aaa83c1d360dd813e8b20d695 173 PRINTS PR01217 Proline rich extensin signature 23 39 1.9E-11 T 06-07-2017 CAK77_RS12155 1e5b6a5aaa83c1d360dd813e8b20d695 173 PRINTS PR01217 Proline rich extensin signature 45 57 1.9E-11 T 06-07-2017 CAK77_RS19465 caedf8b068d238c59debca9308f7245c 156 Pfam PF13452 N-terminal half of MaoC dehydratase 7 137 1.3E-28 T 06-07-2017 CAK77_RS19465 caedf8b068d238c59debca9308f7245c 156 SUPERFAMILY SSF54637 7 148 4.25E-35 T 06-07-2017 IPR029069 HotDog domain CAK77_RS19465 caedf8b068d238c59debca9308f7245c 156 Gene3D G3DSA:3.10.129.10 3 148 1.4E-22 T 06-07-2017 IPR029069 HotDog domain CAK77_RS19465 caedf8b068d238c59debca9308f7245c 156 PIRSF PIRSF018072 1 150 1.1E-55 T 06-07-2017 IPR016709 Uncharacterised protein family UPF0336 CAK77_RS19465 caedf8b068d238c59debca9308f7245c 156 Hamap MF_00799 UPF0336 protein . 1 148 33.624 T 06-07-2017 IPR016709 Uncharacterised protein family UPF0336 CAK77_RS19280 851221908d592d5de335badd076127a3 161 Gene3D G3DSA:3.30.530.20 5 160 3.7E-29 T 06-07-2017 IPR023393 START-like domain CAK77_RS19280 851221908d592d5de335badd076127a3 161 SUPERFAMILY SSF55961 10 160 6.14E-30 T 06-07-2017 CAK77_RS19280 851221908d592d5de335badd076127a3 161 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 23 159 1.4E-16 T 06-07-2017 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CAK77_RS05810 7e1294feea97aa6b4a4a2fca5083aaf0 172 Pfam PF06114 Domain of unknown function (DUF955) 51 135 3.0E-5 T 06-07-2017 IPR010359 HTH domain, IrrE-type CAK77_RS23655 701b48dc026c0b101c2e909eb97bb1d0 143 Gene3D G3DSA:2.30.110.10 6 140 2.3E-23 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS23655 701b48dc026c0b101c2e909eb97bb1d0 143 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 11 88 3.4E-7 T 06-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAK77_RS23655 701b48dc026c0b101c2e909eb97bb1d0 143 SUPERFAMILY SSF50475 4 141 2.99E-22 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS08110 d0e914b7a10d7407fb80defcb928f72c 403 Pfam PF00487 Fatty acid desaturase 65 331 3.0E-34 T 06-07-2017 IPR005804 Fatty acid desaturase domain GO:0006629 CAK77_RS00810 6a98d3483a09f836b1c234c502bfa87a 250 Pfam PF02517 CAAX protease self-immunity 144 233 1.4E-15 T 06-07-2017 IPR003675 CAAX amino terminal protease GO:0016020 CAK77_RS12805 ab55b22892af1b84870234d22353793a 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 61 76 2.3E-6 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK77_RS12805 ab55b22892af1b84870234d22353793a 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 14 29 2.3E-6 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK77_RS12805 ab55b22892af1b84870234d22353793a 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 46 61 2.3E-6 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK77_RS12805 ab55b22892af1b84870234d22353793a 107 Pfam PF01022 Bacterial regulatory protein, arsR family 19 63 9.3E-13 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK77_RS12805 ab55b22892af1b84870234d22353793a 107 SMART SM00418 12 90 9.4E-21 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK77_RS12805 ab55b22892af1b84870234d22353793a 107 Gene3D G3DSA:1.10.10.10 10 93 1.0E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS12805 ab55b22892af1b84870234d22353793a 107 SUPERFAMILY SSF46785 8 91 4.34E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS02950 47f7e500e5706f4383ec333bc1d65f02 162 Pfam PF02559 CarD-like/TRCF domain 3 110 1.5E-16 T 06-07-2017 IPR003711 CarD-like/TRCF domain CAK77_RS02950 47f7e500e5706f4383ec333bc1d65f02 162 SMART SM01058 2 112 2.6E-34 T 06-07-2017 IPR003711 CarD-like/TRCF domain CAK77_RS02950 47f7e500e5706f4383ec333bc1d65f02 162 SUPERFAMILY SSF141259 3 66 2.35E-15 T 06-07-2017 IPR003711 CarD-like/TRCF domain CAK77_RS24000 a5305c466fe8eaf2be5b59bb3c740765 150 SMART SM00347 32 133 2.1E-13 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK77_RS24000 a5305c466fe8eaf2be5b59bb3c740765 150 ProSitePatterns PS01117 MarR-type HTH domain signature. 70 105 - T 06-07-2017 IPR023187 Transcriptional regulator MarR-type, conserved site CAK77_RS24000 a5305c466fe8eaf2be5b59bb3c740765 150 SUPERFAMILY SSF46785 11 140 5.46E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS24000 a5305c466fe8eaf2be5b59bb3c740765 150 Gene3D G3DSA:1.10.10.10 5 140 4.4E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS24000 a5305c466fe8eaf2be5b59bb3c740765 150 Pfam PF12802 MarR family 39 95 6.3E-11 T 06-07-2017 CAK77_RS05080 c32f4bb84339004e1b58811eaf5ef0be 285 Pfam PF02405 Permease MlaE 68 272 1.1E-52 T 06-07-2017 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 CAK77_RS04880 eb3c62c81b24376d4c736b3563d27628 356 SUPERFAMILY SSF53850 78 140 1.9E-17 T 06-07-2017 CAK77_RS04880 eb3c62c81b24376d4c736b3563d27628 356 SUPERFAMILY SSF53850 197 341 1.9E-17 T 06-07-2017 CAK77_RS04880 eb3c62c81b24376d4c736b3563d27628 356 Gene3D G3DSA:3.40.190.10 90 270 4.9E-14 T 06-07-2017 CAK77_RS04880 eb3c62c81b24376d4c736b3563d27628 356 Pfam PF09084 NMT1/THI5 like 90 279 6.8E-7 T 06-07-2017 IPR015168 SsuA/THI5-like CAK77_RS03965 7c34538a64dbb8336bde1abdbe50aadf 289 SMART SM00342 199 282 1.4E-19 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK77_RS03965 7c34538a64dbb8336bde1abdbe50aadf 289 SUPERFAMILY SSF46689 236 285 2.33E-8 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS03965 7c34538a64dbb8336bde1abdbe50aadf 289 Gene3D G3DSA:1.10.10.60 237 285 4.5E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS03965 7c34538a64dbb8336bde1abdbe50aadf 289 Pfam PF12833 Helix-turn-helix domain 205 283 4.3E-22 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK77_RS03965 7c34538a64dbb8336bde1abdbe50aadf 289 Gene3D G3DSA:1.10.10.60 182 236 9.7E-8 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS17250 bb78957cc664121528db48c64d3cfcf4 142 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 27 138 2.8E-22 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CAK77_RS17250 bb78957cc664121528db48c64d3cfcf4 142 Gene3D G3DSA:2.30.110.10 20 120 4.0E-4 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS17250 bb78957cc664121528db48c64d3cfcf4 142 Pfam PF04075 Domain of unknown function (DUF385) 18 137 1.3E-23 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CAK77_RS17250 bb78957cc664121528db48c64d3cfcf4 142 SUPERFAMILY SSF50475 22 137 8.21E-6 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS18640 d909d5dabb22a65e4158c48b38376590 155 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 12 142 1.0E-22 T 06-07-2017 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 CAK77_RS18640 d909d5dabb22a65e4158c48b38376590 155 SUPERFAMILY SSF52540 22 136 3.86E-14 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS18640 d909d5dabb22a65e4158c48b38376590 155 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 12 140 3.3E-30 T 06-07-2017 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 CAK77_RS18640 d909d5dabb22a65e4158c48b38376590 155 Gene3D G3DSA:3.40.50.300 7 153 4.1E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS16830 81f56229e22e648969257a858c968925 297 SMART SM00382 57 262 3.1E-4 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS16830 81f56229e22e648969257a858c968925 297 SUPERFAMILY SSF52540 24 266 2.42E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS16830 81f56229e22e648969257a858c968925 297 Gene3D G3DSA:3.40.50.300 29 269 1.9E-42 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS16830 81f56229e22e648969257a858c968925 297 Pfam PF00005 ABC transporter 50 199 9.3E-25 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK77_RS05435 a0af9225d847a2fb09e67d4c72f20d4d 222 SUPERFAMILY SSF56959 37 221 8.5E-65 T 06-07-2017 IPR016183 Leukocidin/porin GO:0005576|GO:0051715 CAK77_RS05435 a0af9225d847a2fb09e67d4c72f20d4d 222 Gene3D G3DSA:2.60.40.1650 162 221 6.1E-52 T 06-07-2017 CAK77_RS05435 a0af9225d847a2fb09e67d4c72f20d4d 222 Gene3D G3DSA:2.60.40.1650 38 107 6.1E-52 T 06-07-2017 CAK77_RS05435 a0af9225d847a2fb09e67d4c72f20d4d 222 Pfam PF09203 MspA 49 220 5.4E-39 T 06-07-2017 IPR015286 Porin family, mycobacterial-type CAK77_RS05435 a0af9225d847a2fb09e67d4c72f20d4d 222 Gene3D G3DSA:2.10.300.10 108 161 1.9E-24 T 06-07-2017 CAK77_RS15025 c04adaf645d643e3abd2e90069d93b48 242 SUPERFAMILY SSF48008 101 226 4.71E-8 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAK77_RS15025 c04adaf645d643e3abd2e90069d93b48 242 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 74 1.7E-19 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK77_RS15025 c04adaf645d643e3abd2e90069d93b48 242 Gene3D G3DSA:1.20.120.530 89 238 6.7E-12 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAK77_RS15025 c04adaf645d643e3abd2e90069d93b48 242 Pfam PF07729 FCD domain 104 224 1.9E-7 T 06-07-2017 IPR011711 GntR, C-terminal CAK77_RS15025 c04adaf645d643e3abd2e90069d93b48 242 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 6.8E-11 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK77_RS15025 c04adaf645d643e3abd2e90069d93b48 242 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 6.8E-11 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK77_RS15025 c04adaf645d643e3abd2e90069d93b48 242 SMART SM00345 15 74 3.0E-17 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAK77_RS15025 c04adaf645d643e3abd2e90069d93b48 242 Gene3D G3DSA:1.10.10.10 7 76 9.1E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS15025 c04adaf645d643e3abd2e90069d93b48 242 SUPERFAMILY SSF46785 4 78 8.52E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS16080 0c138f2f9292a1b11112fff6d49662bf 339 SUPERFAMILY SSF51679 2 329 1.44E-68 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS16080 0c138f2f9292a1b11112fff6d49662bf 339 Gene3D G3DSA:3.20.20.30 2 330 5.8E-78 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS16080 0c138f2f9292a1b11112fff6d49662bf 339 Pfam PF00296 Luciferase-like monooxygenase 13 298 1.1E-41 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS04295 8e8551ad8f35d73e3605db40e90dc18c 389 Gene3D G3DSA:3.90.1150.10 254 387 3.2E-25 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK77_RS04295 8e8551ad8f35d73e3605db40e90dc18c 389 Pfam PF00155 Aminotransferase class I and II 28 384 3.0E-61 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAK77_RS04295 8e8551ad8f35d73e3605db40e90dc18c 389 SUPERFAMILY SSF53383 7 387 1.29E-104 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK77_RS04295 8e8551ad8f35d73e3605db40e90dc18c 389 Gene3D G3DSA:3.40.640.10 42 253 2.1E-72 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK77_RS03340 144cf130c6dc67b23b052a20c59b1273 166 Gene3D G3DSA:2.60.120.10 38 149 1.5E-25 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK77_RS03340 144cf130c6dc67b23b052a20c59b1273 166 SUPERFAMILY SSF51182 31 158 2.3E-19 T 06-07-2017 IPR011051 RmlC-like cupin domain CAK77_RS03340 144cf130c6dc67b23b052a20c59b1273 166 Pfam PF07883 Cupin domain 69 130 7.6E-13 T 06-07-2017 IPR013096 Cupin 2, conserved barrel CAK77_RS09700 005eb93a5d67a64ddf1b0e22aabab215 219 SUPERFAMILY SSF55729 119 204 1.26E-10 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS09700 005eb93a5d67a64ddf1b0e22aabab215 219 SUPERFAMILY SSF55729 78 87 1.26E-10 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS09700 005eb93a5d67a64ddf1b0e22aabab215 219 Pfam PF00583 Acetyltransferase (GNAT) family 78 177 1.3E-6 T 06-07-2017 IPR000182 GNAT domain GO:0008080 CAK77_RS09700 005eb93a5d67a64ddf1b0e22aabab215 219 Gene3D G3DSA:3.40.630.30 74 200 1.7E-12 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS03625 59777a0f157f772b73d7e1499b6aae4c 335 Pfam PF04261 Dyp-type peroxidase family 7 303 1.3E-95 T 06-07-2017 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 CAK77_RS03625 59777a0f157f772b73d7e1499b6aae4c 335 SUPERFAMILY SSF54909 5 305 4.11E-105 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAK77_RS03625 59777a0f157f772b73d7e1499b6aae4c 335 TIGRFAM TIGR04537 encap_target: encapsulation C-terminal sorting signal 323 332 0.11 T 06-07-2017 CAK77_RS03625 59777a0f157f772b73d7e1499b6aae4c 335 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 7 303 1.0E-85 T 06-07-2017 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 CAK77_RS16345 3ce70c5280f86d11fd48566ab36eaa1c 226 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 11 224 33.508 T 06-07-2017 IPR002043 Uracil-DNA glycosylase GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CAK77_RS16345 3ce70c5280f86d11fd48566ab36eaa1c 226 Gene3D G3DSA:3.40.470.10 6 225 8.3E-79 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CAK77_RS16345 3ce70c5280f86d11fd48566ab36eaa1c 226 Pfam PF03167 Uracil DNA glycosylase superfamily 55 212 5.8E-18 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CAK77_RS16345 3ce70c5280f86d11fd48566ab36eaa1c 226 SMART SM00987 53 213 8.7E-32 T 06-07-2017 CAK77_RS16345 3ce70c5280f86d11fd48566ab36eaa1c 226 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 61 70 - T 06-07-2017 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CAK77_RS16345 3ce70c5280f86d11fd48566ab36eaa1c 226 SMART SM00986 53 213 8.7E-32 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CAK77_RS16345 3ce70c5280f86d11fd48566ab36eaa1c 226 TIGRFAM TIGR00628 ung: uracil-DNA glycosylase 14 213 1.2E-56 T 06-07-2017 IPR002043 Uracil-DNA glycosylase GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CAK77_RS16345 3ce70c5280f86d11fd48566ab36eaa1c 226 SUPERFAMILY SSF52141 9 225 2.24E-71 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CAK77_RS13465 67fbe2d6a1145b5190b403029343f26a 398 TIGRFAM TIGR01981 sufD: FeS assembly protein SufD 108 385 3.5E-74 T 06-07-2017 IPR011542 SUF system FeS cluster assembly, SufD GO:0016226 CAK77_RS13465 67fbe2d6a1145b5190b403029343f26a 398 SUPERFAMILY SSF101960 36 393 2.22E-84 T 06-07-2017 CAK77_RS13465 67fbe2d6a1145b5190b403029343f26a 398 Pfam PF01458 Uncharacterized protein family (UPF0051) 142 368 1.7E-68 T 06-07-2017 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 CAK77_RS13075 e79d80e6873036f19618fe07236baa3f 216 SUPERFAMILY SSF52317 7 213 8.48E-53 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAK77_RS13075 e79d80e6873036f19618fe07236baa3f 216 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 7 214 31.734 T 06-07-2017 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 CAK77_RS13075 e79d80e6873036f19618fe07236baa3f 216 Gene3D G3DSA:3.40.50.880 6 213 1.3E-72 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAK77_RS13075 e79d80e6873036f19618fe07236baa3f 216 Pfam PF00117 Glutamine amidotransferase class-I 10 203 2.7E-16 T 06-07-2017 IPR017926 Glutamine amidotransferase CAK77_RS13075 e79d80e6873036f19618fe07236baa3f 216 PIRSF PIRSF000495 6 216 1.2E-59 T 06-07-2017 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 CAK77_RS13075 e79d80e6873036f19618fe07236baa3f 216 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 8 213 2.8E-62 T 06-07-2017 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 CAK77_RS22445 2007bd52a81d349bb5aaa1341006bacb 619 Pfam PF10101 Predicted membrane protein (DUF2339) 287 603 5.0E-15 T 06-07-2017 IPR019286 Protein of unknown function DUF2339, transmembrane CAK77_RS21545 12098214538e91ddcd03c179f78b7a2d 497 Pfam PF01926 50S ribosome-binding GTPase 46 179 3.4E-9 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 CAK77_RS21545 12098214538e91ddcd03c179f78b7a2d 497 Gene3D G3DSA:3.40.50.300 33 89 5.3E-15 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS21545 12098214538e91ddcd03c179f78b7a2d 497 Gene3D G3DSA:3.40.50.300 137 220 5.3E-15 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS21545 12098214538e91ddcd03c179f78b7a2d 497 SUPERFAMILY SSF52540 32 219 3.93E-21 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS02910 f368a3c92dd9a4be71eb1bb26ec3aeec 514 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 379 464 1.3E-12 T 06-07-2017 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain CAK77_RS02910 f368a3c92dd9a4be71eb1bb26ec3aeec 514 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 112 284 2.1E-40 T 06-07-2017 IPR004474 Cell envelope-related transcriptional attenuator domain CAK77_RS02910 f368a3c92dd9a4be71eb1bb26ec3aeec 514 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 112 283 1.2E-28 T 06-07-2017 IPR004474 Cell envelope-related transcriptional attenuator domain CAK77_RS15440 c3f7a75ed5234d479d8d15063aa31c01 506 Gene3D G3DSA:3.50.50.60 6 190 1.0E-48 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS15440 c3f7a75ed5234d479d8d15063aa31c01 506 Gene3D G3DSA:3.50.50.60 382 487 1.0E-48 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS15440 c3f7a75ed5234d479d8d15063aa31c01 506 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 16 212 7.2E-14 T 06-07-2017 CAK77_RS15440 c3f7a75ed5234d479d8d15063aa31c01 506 SUPERFAMILY SSF51905 282 457 1.29E-12 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS15440 c3f7a75ed5234d479d8d15063aa31c01 506 SUPERFAMILY SSF51905 10 221 2.47E-37 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS01805 42de7c493f89689ba29465e47bbe7b25 220 Pfam PF14032 PknH-like extracellular domain 29 209 7.4E-28 T 06-07-2017 IPR026954 PknH-like extracellular domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 CAK77_RS05095 ff8951264832034796f5e3a500ee9b13 381 Pfam PF00534 Glycosyl transferases group 1 212 344 3.0E-24 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 CAK77_RS05095 ff8951264832034796f5e3a500ee9b13 381 Gene3D G3DSA:3.40.50.2000 212 349 3.3E-19 T 06-07-2017 CAK77_RS05095 ff8951264832034796f5e3a500ee9b13 381 Pfam PF13439 Glycosyltransferase Family 4 99 203 1.4E-10 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 CAK77_RS05095 ff8951264832034796f5e3a500ee9b13 381 SUPERFAMILY SSF53756 5 377 4.32E-54 T 06-07-2017 CAK77_RS21680 b71649ef0cf6b1287e7a1213beb0863c 967 Pfam PF03176 MMPL family 53 381 3.0E-97 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 CAK77_RS21680 b71649ef0cf6b1287e7a1213beb0863c 967 Pfam PF03176 MMPL family 604 937 1.6E-92 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 CAK77_RS21680 b71649ef0cf6b1287e7a1213beb0863c 967 SUPERFAMILY SSF82866 152 349 1.96E-24 T 06-07-2017 CAK77_RS21680 b71649ef0cf6b1287e7a1213beb0863c 967 Gene3D G3DSA:1.20.1640.10 730 928 1.3E-19 T 06-07-2017 CAK77_RS21680 b71649ef0cf6b1287e7a1213beb0863c 967 Gene3D G3DSA:1.20.1640.10 151 353 1.1E-24 T 06-07-2017 CAK77_RS21680 b71649ef0cf6b1287e7a1213beb0863c 967 SUPERFAMILY SSF82866 707 928 7.32E-28 T 06-07-2017 CAK77_RS21680 b71649ef0cf6b1287e7a1213beb0863c 967 TIGRFAM TIGR00833 actII: transport protein 21 928 1.7E-287 T 06-07-2017 IPR004707 Membrane transport protein MmpL family GO:0016021 CAK77_RS13760 13cfe4812d5db180271f45809895b3cc 311 Gene3D G3DSA:3.40.50.1820 7 309 3.9E-94 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS13760 13cfe4812d5db180271f45809895b3cc 311 Pfam PF07859 alpha/beta hydrolase fold 80 285 1.7E-69 T 06-07-2017 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CAK77_RS13760 13cfe4812d5db180271f45809895b3cc 311 ProSitePatterns PS01173 Lipolytic enzymes "G-D-X-G" family, putative histidine active site. 79 95 - T 06-07-2017 IPR002168 Lipase, GDXG, putative histidine active site GO:0008152|GO:0016787 Reactome: R-HSA-163560 CAK77_RS13760 13cfe4812d5db180271f45809895b3cc 311 SUPERFAMILY SSF53474 22 309 4.78E-71 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS03505 14962b3f4f4f425bc41fc7f2e74e5bd5 134 SUPERFAMILY SSF54197 3 131 2.32E-33 T 06-07-2017 IPR011146 HIT-like domain GO:0003824 CAK77_RS03505 14962b3f4f4f425bc41fc7f2e74e5bd5 134 Pfam PF01230 HIT domain 11 101 3.6E-23 T 06-07-2017 IPR001310 Histidine triad (HIT) protein CAK77_RS03505 14962b3f4f4f425bc41fc7f2e74e5bd5 134 Gene3D G3DSA:3.30.428.10 2 125 6.1E-28 T 06-07-2017 IPR011146 HIT-like domain GO:0003824 CAK77_RS03505 14962b3f4f4f425bc41fc7f2e74e5bd5 134 PRINTS PR00332 Histidine triad family signature 4 20 5.3E-14 T 06-07-2017 IPR001310 Histidine triad (HIT) protein CAK77_RS03505 14962b3f4f4f425bc41fc7f2e74e5bd5 134 PRINTS PR00332 Histidine triad family signature 25 43 5.3E-14 T 06-07-2017 IPR001310 Histidine triad (HIT) protein CAK77_RS03505 14962b3f4f4f425bc41fc7f2e74e5bd5 134 PRINTS PR00332 Histidine triad family signature 87 97 5.3E-14 T 06-07-2017 IPR001310 Histidine triad (HIT) protein CAK77_RS01510 5df53d4b15b8c2aafb1336b08214955d 541 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 201 216 - T 06-07-2017 IPR019826 Carboxylesterase type B, active site CAK77_RS01510 5df53d4b15b8c2aafb1336b08214955d 541 SUPERFAMILY SSF53474 31 517 3.38E-95 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS01510 5df53d4b15b8c2aafb1336b08214955d 541 Pfam PF00135 Carboxylesterase family 31 512 5.5E-84 T 06-07-2017 IPR002018 Carboxylesterase, type B CAK77_RS01510 5df53d4b15b8c2aafb1336b08214955d 541 Gene3D G3DSA:3.40.50.1820 28 516 5.3E-112 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS13425 f9c2ba8ee8c2cd11ef4c2d5478f60b15 375 SUPERFAMILY SSF51395 7 359 7.63E-92 T 06-07-2017 CAK77_RS13425 f9c2ba8ee8c2cd11ef4c2d5478f60b15 375 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 11 359 3.1E-66 T 06-07-2017 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 CAK77_RS13425 f9c2ba8ee8c2cd11ef4c2d5478f60b15 375 Gene3D G3DSA:3.20.20.70 6 359 7.6E-97 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK77_RS12175 1d0e1d617801a397b73405e1b8f3f4ef 188 Pfam PF01814 Hemerythrin HHE cation binding domain 15 131 2.1E-6 T 06-07-2017 IPR012312 Haemerythrin-like Reactome: R-HSA-390471 CAK77_RS23625 ce22270fa31182af772eb995fe8e09a8 358 Gene3D G3DSA:3.40.50.150 174 352 8.0E-34 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS23625 ce22270fa31182af772eb995fe8e09a8 358 SUPERFAMILY SSF53335 166 354 6.41E-33 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS23625 ce22270fa31182af772eb995fe8e09a8 358 Pfam PF13847 Methyltransferase domain 175 291 7.9E-29 T 06-07-2017 IPR025714 Methyltransferase domain CAK77_RS23650 be431644564739b9098e0b0786a6dc30 89 Pfam PF02583 Metal-sensitive transcriptional repressor 10 81 8.4E-24 T 06-07-2017 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 CAK77_RS01965 109ba2ac66aaabf4a8f4ff48966034fd 379 Pfam PF14258 Domain of unknown function (DUF4350) 54 115 1.3E-7 T 06-07-2017 IPR025646 Domain of unknown function DUF4350 CAK77_RS04660 d1927e9100875db9681339f7ec3ce7f4 489 Pfam PF13450 NAD(P)-binding Rossmann-like domain 13 52 1.1E-7 T 06-07-2017 CAK77_RS04660 d1927e9100875db9681339f7ec3ce7f4 489 SUPERFAMILY SSF51905 6 289 3.89E-26 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS04660 d1927e9100875db9681339f7ec3ce7f4 489 Gene3D G3DSA:3.50.50.60 6 75 2.8E-22 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS04660 d1927e9100875db9681339f7ec3ce7f4 489 Gene3D G3DSA:3.50.50.60 181 273 2.8E-22 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS06880 641a528fbc6fdc240e214563d18e2548 277 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 86 269 3.9E-19 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS06880 641a528fbc6fdc240e214563d18e2548 277 Gene3D G3DSA:1.10.3720.10 12 264 4.0E-61 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS06880 641a528fbc6fdc240e214563d18e2548 277 SUPERFAMILY SSF161098 7 277 2.49E-70 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS01920 74ffe30bbb90a6b989655e506268f4b0 267 ProSitePatterns PS00221 MIP family signature. 61 69 - T 06-07-2017 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CAK77_RS01920 74ffe30bbb90a6b989655e506268f4b0 267 Pfam PF00230 Major intrinsic protein 3 240 5.5E-51 T 06-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CAK77_RS01920 74ffe30bbb90a6b989655e506268f4b0 267 SUPERFAMILY SSF81338 3 244 2.09E-66 T 06-07-2017 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CAK77_RS01920 74ffe30bbb90a6b989655e506268f4b0 267 TIGRFAM TIGR00861 MIP: MIP family channel proteins 6 240 1.8E-62 T 06-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CAK77_RS01920 74ffe30bbb90a6b989655e506268f4b0 267 Gene3D G3DSA:1.20.1080.10 3 246 1.2E-77 T 06-07-2017 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CAK77_RS01920 74ffe30bbb90a6b989655e506268f4b0 267 PRINTS PR00783 Major intrinsic protein family signature 2 21 1.4E-47 T 06-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CAK77_RS01920 74ffe30bbb90a6b989655e506268f4b0 267 PRINTS PR00783 Major intrinsic protein family signature 43 67 1.4E-47 T 06-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CAK77_RS01920 74ffe30bbb90a6b989655e506268f4b0 267 PRINTS PR00783 Major intrinsic protein family signature 141 159 1.4E-47 T 06-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CAK77_RS01920 74ffe30bbb90a6b989655e506268f4b0 267 PRINTS PR00783 Major intrinsic protein family signature 174 196 1.4E-47 T 06-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CAK77_RS01920 74ffe30bbb90a6b989655e506268f4b0 267 PRINTS PR00783 Major intrinsic protein family signature 223 243 1.4E-47 T 06-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CAK77_RS01920 74ffe30bbb90a6b989655e506268f4b0 267 PRINTS PR00783 Major intrinsic protein family signature 80 99 1.4E-47 T 06-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CAK77_RS11150 2ee4e69e7315304922b740613fd06ad1 373 Gene3D G3DSA:3.40.50.720 6 76 3.7E-12 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS11150 2ee4e69e7315304922b740613fd06ad1 373 SUPERFAMILY SSF51735 5 155 3.61E-14 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS18885 abc8052fff092c32ebb68c8a166c0435 424 SUPERFAMILY SSF56784 163 344 6.92E-13 T 06-07-2017 IPR023214 HAD-like domain CAK77_RS18885 abc8052fff092c32ebb68c8a166c0435 424 SUPERFAMILY SSF56784 71 85 6.92E-13 T 06-07-2017 IPR023214 HAD-like domain CAK77_RS18885 abc8052fff092c32ebb68c8a166c0435 424 Gene3D G3DSA:3.40.50.1000 70 87 5.0E-9 T 06-07-2017 IPR023214 HAD-like domain CAK77_RS18885 abc8052fff092c32ebb68c8a166c0435 424 Gene3D G3DSA:3.40.50.1000 218 346 5.0E-9 T 06-07-2017 IPR023214 HAD-like domain CAK77_RS10435 7ec633e69a1c917c218e775d5cf0acbf 535 Pfam PF00361 Proton-conducting membrane transporter 139 446 1.8E-58 T 06-07-2017 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS10435 7ec633e69a1c917c218e775d5cf0acbf 535 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 9 512 4.1E-160 T 06-07-2017 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS10435 7ec633e69a1c917c218e775d5cf0acbf 535 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 352 371 2.2E-29 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS10435 7ec633e69a1c917c218e775d5cf0acbf 535 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 404 430 2.2E-29 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS10435 7ec633e69a1c917c218e775d5cf0acbf 535 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 264 288 2.2E-29 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS10435 7ec633e69a1c917c218e775d5cf0acbf 535 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 180 204 2.2E-29 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS10435 7ec633e69a1c917c218e775d5cf0acbf 535 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 145 164 2.2E-29 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS09415 a38d763c5bbc4194d1d85fe042f22216 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 3.1E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS09415 a38d763c5bbc4194d1d85fe042f22216 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 3.1E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS09415 a38d763c5bbc4194d1d85fe042f22216 214 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 67 8.2E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS09415 a38d763c5bbc4194d1d85fe042f22216 214 Gene3D G3DSA:1.10.357.10 19 166 1.7E-20 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS09415 a38d763c5bbc4194d1d85fe042f22216 214 SUPERFAMILY SSF46689 13 83 3.19E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS10650 d874fc198beb275f115e4cc3e9b8f95e 91 Pfam PF02416 mttA/Hcf106 family 9 56 3.9E-21 T 06-07-2017 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 CAK77_RS10650 d874fc198beb275f115e4cc3e9b8f95e 91 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 4 90 21.039 T 06-07-2017 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 CAK77_RS10650 d874fc198beb275f115e4cc3e9b8f95e 91 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 6 52 1.2E-20 T 06-07-2017 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 CAK77_RS16660 9fa4c45817efed8c1104fd637c4f2108 295 Pfam PF00378 Enoyl-CoA hydratase/isomerase 33 294 1.5E-42 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAK77_RS16660 9fa4c45817efed8c1104fd637c4f2108 295 Gene3D G3DSA:1.10.12.10 237 294 1.0E-22 T 06-07-2017 IPR014748 Crontonase, C-terminal CAK77_RS16660 9fa4c45817efed8c1104fd637c4f2108 295 Gene3D G3DSA:3.90.226.10 28 236 1.6E-57 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS16660 9fa4c45817efed8c1104fd637c4f2108 295 SUPERFAMILY SSF52096 25 295 1.9E-72 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS05325 afc2d1a921699bb40a0ef7fc59db6112 282 TIGRFAM TIGR03619 F420_Rv2161c: probable F420-dependent oxidoreductase, Rv2161c family 19 257 6.0E-75 T 06-07-2017 IPR019921 Luciferase-like, F420-dependent oxidoreductase, Rv2161c, predicted CAK77_RS05325 afc2d1a921699bb40a0ef7fc59db6112 282 SUPERFAMILY SSF51679 20 274 1.26E-57 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS05325 afc2d1a921699bb40a0ef7fc59db6112 282 Pfam PF00296 Luciferase-like monooxygenase 20 234 1.3E-50 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS05325 afc2d1a921699bb40a0ef7fc59db6112 282 Gene3D G3DSA:3.20.20.30 20 234 3.8E-60 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS08295 c80f21524ad6d003fe3b65e38a1cd535 269 Pfam PF12836 Helix-hairpin-helix motif 208 267 2.1E-22 T 06-07-2017 CAK77_RS08295 c80f21524ad6d003fe3b65e38a1cd535 269 Gene3D G3DSA:1.10.150.280 200 269 7.9E-19 T 06-07-2017 CAK77_RS08295 c80f21524ad6d003fe3b65e38a1cd535 269 Pfam PF10531 SLBB domain 117 169 5.3E-8 T 06-07-2017 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS08295 c80f21524ad6d003fe3b65e38a1cd535 269 SUPERFAMILY SSF47781 202 269 1.56E-26 T 06-07-2017 IPR010994 RuvA domain 2-like CAK77_RS08295 c80f21524ad6d003fe3b65e38a1cd535 269 SMART SM00278 217 236 0.3 T 06-07-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CAK77_RS08295 c80f21524ad6d003fe3b65e38a1cd535 269 SMART SM00278 247 266 4.3 T 06-07-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CAK77_RS08295 c80f21524ad6d003fe3b65e38a1cd535 269 Gene3D G3DSA:3.10.560.10 110 170 1.9E-6 T 06-07-2017 CAK77_RS08295 c80f21524ad6d003fe3b65e38a1cd535 269 TIGRFAM TIGR00426 TIGR00426: competence protein ComEA helix-hairpin-helix repeat region 207 268 7.3E-17 T 06-07-2017 IPR004509 Competence protein ComEA, helix-hairpin-helix domain CAK77_RS22700 d9c091119513bf900805f8eee4a9f3ce 248 Pfam PF02678 Pirin 10 127 3.2E-32 T 06-07-2017 IPR003829 Pirin, N-terminal domain CAK77_RS22700 d9c091119513bf900805f8eee4a9f3ce 248 Gene3D G3DSA:2.60.120.10 5 243 1.0E-59 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK77_RS22700 d9c091119513bf900805f8eee4a9f3ce 248 SUPERFAMILY SSF51182 4 242 6.43E-58 T 06-07-2017 IPR011051 RmlC-like cupin domain CAK77_RS22700 d9c091119513bf900805f8eee4a9f3ce 248 PIRSF PIRSF006232 2 241 1.0E-45 T 06-07-2017 IPR012093 Pirin CAK77_RS04860 3ec3841bce4567565b22badfd97c4689 151 Pfam PF05423 Mycobacterium membrane protein 13 151 6.1E-44 T 06-07-2017 IPR008693 Transport accessory protein MmpS CAK77_RS11525 d2a4dfcbee07c84aeda100edbba4267a 293 Gene3D G3DSA:3.40.50.300 40 292 2.7E-68 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS11525 d2a4dfcbee07c84aeda100edbba4267a 293 SUPERFAMILY SSF52540 39 291 1.89E-64 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS11525 d2a4dfcbee07c84aeda100edbba4267a 293 Pfam PF13614 AAA domain 40 215 2.3E-59 T 06-07-2017 IPR025669 AAA domain CAK77_RS14575 aea2cbb1a9cb9a78e358bd7c8a80c961 271 Gene3D G3DSA:3.60.110.10 4 264 2.4E-60 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAK77_RS14575 aea2cbb1a9cb9a78e358bd7c8a80c961 271 SUPERFAMILY SSF56317 5 263 1.83E-60 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAK77_RS14575 aea2cbb1a9cb9a78e358bd7c8a80c961 271 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 142 162 - T 06-07-2017 IPR001110 Uncharacterised protein family UPF0012, conserved site CAK77_RS14575 aea2cbb1a9cb9a78e358bd7c8a80c961 271 Pfam PF00795 Carbon-nitrogen hydrolase 8 245 1.2E-43 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAK77_RS12230 373c29901fb213598aed9ed7a14aea93 268 Pfam PF14907 Uncharacterised nucleotidyltransferase 3 170 1.5E-9 T 06-07-2017 CAK77_RS12230 373c29901fb213598aed9ed7a14aea93 268 SUPERFAMILY SSF81301 1 137 7.19E-29 T 06-07-2017 CAK77_RS10855 72059bbbb55aee9c5f29065f742be95d 287 Pfam PF14011 EspG family 14 265 3.8E-57 T 06-07-2017 IPR025734 EspG family CAK77_RS17735 fe7e003d10419ea3c511cf675ef86a2f 72 Gene3D G3DSA:2.40.50.100 3 71 2.7E-20 T 06-07-2017 CAK77_RS17735 fe7e003d10419ea3c511cf675ef86a2f 72 Pfam PF00364 Biotin-requiring enzyme 10 70 3.6E-17 T 06-07-2017 IPR000089 Biotin/lipoyl attachment CAK77_RS17735 fe7e003d10419ea3c511cf675ef86a2f 72 SUPERFAMILY SSF51230 4 71 2.62E-18 T 06-07-2017 IPR011053 Single hybrid motif CAK77_RS22115 a28fd384ce4f1fa6a926d561d24047d8 338 Gene3D G3DSA:2.60.120.330 19 291 4.9E-77 T 06-07-2017 IPR027443 Isopenicillin N synthase-like CAK77_RS22115 a28fd384ce4f1fa6a926d561d24047d8 338 PRINTS PR00682 Isopenicillin N synthase signature 268 286 1.9E-8 T 06-07-2017 IPR002283 Isopenicillin N synthase GO:0005506|GO:0016491|GO:0055114 CAK77_RS22115 a28fd384ce4f1fa6a926d561d24047d8 338 PRINTS PR00682 Isopenicillin N synthase signature 206 227 1.9E-8 T 06-07-2017 IPR002283 Isopenicillin N synthase GO:0005506|GO:0016491|GO:0055114 CAK77_RS22115 a28fd384ce4f1fa6a926d561d24047d8 338 PRINTS PR00682 Isopenicillin N synthase signature 241 267 1.9E-8 T 06-07-2017 IPR002283 Isopenicillin N synthase GO:0005506|GO:0016491|GO:0055114 CAK77_RS22115 a28fd384ce4f1fa6a926d561d24047d8 338 PRINTS PR00682 Isopenicillin N synthase signature 37 54 1.9E-8 T 06-07-2017 IPR002283 Isopenicillin N synthase GO:0005506|GO:0016491|GO:0055114 CAK77_RS22115 a28fd384ce4f1fa6a926d561d24047d8 338 Pfam PF14226 non-haem dioxygenase in morphine synthesis N-terminal 21 137 2.1E-31 T 06-07-2017 IPR026992 Non-haem dioxygenase N-terminal domain CAK77_RS22115 a28fd384ce4f1fa6a926d561d24047d8 338 SUPERFAMILY SSF51197 18 290 4.26E-73 T 06-07-2017 CAK77_RS22115 a28fd384ce4f1fa6a926d561d24047d8 338 Pfam PF03171 2OG-Fe(II) oxygenase superfamily 189 280 5.2E-19 T 06-07-2017 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 CAK77_RS07100 0f9b1c87b0753f4f9c48d5c94d4309aa 185 Pfam PF12079 Protein of unknown function (DUF3558) 23 181 1.7E-29 T 06-07-2017 IPR024520 Protein of unknown function DUF3558 CAK77_RS09845 29bdbd55d37d2e7cdb4c78a131469257 437 Gene3D G3DSA:3.40.47.10 289 435 9.1E-50 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS09845 29bdbd55d37d2e7cdb4c78a131469257 437 SUPERFAMILY SSF53901 242 435 1.67E-61 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS09845 29bdbd55d37d2e7cdb4c78a131469257 437 SMART SM00825 Beta-ketoacyl synthase 13 436 3.5E-13 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAK77_RS09845 29bdbd55d37d2e7cdb4c78a131469257 437 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 11 271 1.5E-34 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAK77_RS09845 29bdbd55d37d2e7cdb4c78a131469257 437 Gene3D G3DSA:3.40.47.10 13 284 2.9E-44 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS09845 29bdbd55d37d2e7cdb4c78a131469257 437 SUPERFAMILY SSF53901 9 276 1.07E-44 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS09845 29bdbd55d37d2e7cdb4c78a131469257 437 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 279 393 3.2E-31 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAK77_RS01350 67df2704c36a034a73ed501a6c5a0193 217 Gene3D G3DSA:1.10.3720.10 9 193 7.5E-22 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS01350 67df2704c36a034a73ed501a6c5a0193 217 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 30 198 1.3E-16 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS01350 67df2704c36a034a73ed501a6c5a0193 217 SUPERFAMILY SSF161098 11 195 5.36E-29 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS12430 ec9a79d97c4ec1422757aef93b5c3df4 621 Gene3D G3DSA:3.40.449.10 20 250 8.0E-95 T 06-07-2017 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CAK77_RS12430 ec9a79d97c4ec1422757aef93b5c3df4 621 ProSitePatterns PS00505 Phosphoenolpyruvate carboxykinase (GTP) signature. 275 283 - T 06-07-2017 IPR018091 Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site GO:0004613 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 CAK77_RS12430 ec9a79d97c4ec1422757aef93b5c3df4 621 Hamap MF_00452 Phosphoenolpyruvate carboxykinase [GTP] [pckG]. 18 613 49.086 T 06-07-2017 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 CAK77_RS12430 ec9a79d97c4ec1422757aef93b5c3df4 621 SUPERFAMILY SSF53795 251 612 4.81E-154 T 06-07-2017 CAK77_RS12430 ec9a79d97c4ec1422757aef93b5c3df4 621 PIRSF PIRSF001348 8 616 6.8E-273 T 06-07-2017 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 CAK77_RS12430 ec9a79d97c4ec1422757aef93b5c3df4 621 Gene3D G3DSA:3.90.228.20 251 320 9.5E-32 T 06-07-2017 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CAK77_RS12430 ec9a79d97c4ec1422757aef93b5c3df4 621 Gene3D G3DSA:3.90.228.20 345 614 2.6E-91 T 06-07-2017 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CAK77_RS12430 ec9a79d97c4ec1422757aef93b5c3df4 621 SUPERFAMILY SSF68923 20 250 1.73E-96 T 06-07-2017 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CAK77_RS12430 ec9a79d97c4ec1422757aef93b5c3df4 621 Pfam PF00821 Phosphoenolpyruvate carboxykinase 30 612 2.6E-274 T 06-07-2017 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 CAK77_RS20890 81e64b77a8390ececdb79ef2afe24057 351 SUPERFAMILY SSF53901 1 222 3.78E-12 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS20890 81e64b77a8390ececdb79ef2afe24057 351 SUPERFAMILY SSF53901 226 339 2.26E-10 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS03370 a175804439d46e95bbb4bd148145caf4 541 ProSitePatterns PS00296 Chaperonins cpn60 signature. 403 414 - T 06-07-2017 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020 CAK77_RS03370 a175804439d46e95bbb4bd148145caf4 541 Hamap MF_00600 60 kDa chaperonin [groL]. 1 539 41.045 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 CAK77_RS03370 a175804439d46e95bbb4bd148145caf4 541 Gene3D G3DSA:1.10.560.10 367 515 9.2E-39 T 06-07-2017 IPR027413 GroEL-like equatorial domain CAK77_RS03370 a175804439d46e95bbb4bd148145caf4 541 SUPERFAMILY SSF48592 6 133 1.08E-73 T 06-07-2017 CAK77_RS03370 a175804439d46e95bbb4bd148145caf4 541 SUPERFAMILY SSF48592 404 518 1.08E-73 T 06-07-2017 CAK77_RS03370 a175804439d46e95bbb4bd148145caf4 541 Gene3D G3DSA:1.10.560.10 3 186 1.7E-48 T 06-07-2017 IPR027413 GroEL-like equatorial domain CAK77_RS03370 a175804439d46e95bbb4bd148145caf4 541 SUPERFAMILY SSF52029 184 374 3.44E-81 T 06-07-2017 IPR027409 GroEL-like apical domain CAK77_RS03370 a175804439d46e95bbb4bd148145caf4 541 PRINTS PR00298 60kDa chaperonin signature 26 52 4.3E-71 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 CAK77_RS03370 a175804439d46e95bbb4bd148145caf4 541 PRINTS PR00298 60kDa chaperonin signature 348 373 4.3E-71 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 CAK77_RS03370 a175804439d46e95bbb4bd148145caf4 541 PRINTS PR00298 60kDa chaperonin signature 266 289 4.3E-71 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 CAK77_RS03370 a175804439d46e95bbb4bd148145caf4 541 PRINTS PR00298 60kDa chaperonin signature 82 109 4.3E-71 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 CAK77_RS03370 a175804439d46e95bbb4bd148145caf4 541 PRINTS PR00298 60kDa chaperonin signature 396 417 4.3E-71 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 CAK77_RS03370 a175804439d46e95bbb4bd148145caf4 541 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 524 1.6E-249 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 CAK77_RS03370 a175804439d46e95bbb4bd148145caf4 541 SUPERFAMILY SSF54849 136 201 3.66E-27 T 06-07-2017 CAK77_RS03370 a175804439d46e95bbb4bd148145caf4 541 Gene3D G3DSA:3.50.7.10 187 366 1.1E-96 T 06-07-2017 IPR027409 GroEL-like apical domain CAK77_RS03370 a175804439d46e95bbb4bd148145caf4 541 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 522 2.3E-96 T 06-07-2017 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 CAK77_RS11980 e3e47890b8f657107e5082e3339e1c11 209 Gene3D G3DSA:1.10.357.10 9 199 1.7E-25 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS11980 e3e47890b8f657107e5082e3339e1c11 209 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 55 1.9E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS11980 e3e47890b8f657107e5082e3339e1c11 209 SUPERFAMILY SSF46689 3 75 1.28E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS19120 de41666405415f29e233386e6aa02279 482 SUPERFAMILY SSF53448 94 339 8.7E-48 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK77_RS19120 de41666405415f29e233386e6aa02279 482 Pfam PF00535 Glycosyl transferase family 2 97 257 5.9E-23 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CAK77_RS19120 de41666405415f29e233386e6aa02279 482 TIGRFAM TIGR03965 mycofact_glyco: mycofactocin system glycosyltransferase 24 481 2.4E-183 T 06-07-2017 IPR023981 Putative mycofactocin biosynthesis glycosyltransferase CAK77_RS19120 de41666405415f29e233386e6aa02279 482 Gene3D G3DSA:3.90.550.10 96 296 1.4E-36 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK77_RS04515 978b2797888a1370e748695838ad6134 492 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 10 216 2.2E-16 T 06-07-2017 CAK77_RS04515 978b2797888a1370e748695838ad6134 492 SUPERFAMILY SSF51905 291 409 5.18E-58 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS04515 978b2797888a1370e748695838ad6134 492 SUPERFAMILY SSF51905 7 225 5.18E-58 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS04515 978b2797888a1370e748695838ad6134 492 PRINTS PR00419 Adrenodoxin reductase family signature 172 186 1.4E-5 T 06-07-2017 CAK77_RS04515 978b2797888a1370e748695838ad6134 492 PRINTS PR00419 Adrenodoxin reductase family signature 7 29 1.4E-5 T 06-07-2017 CAK77_RS04515 978b2797888a1370e748695838ad6134 492 Gene3D G3DSA:3.50.50.60 292 472 1.5E-16 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS04515 978b2797888a1370e748695838ad6134 492 Gene3D G3DSA:3.50.50.60 6 214 7.6E-63 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS13715 30bfc4b4f9205c585918bc9f556ff36d 243 Gene3D G3DSA:2.40.10.10 37 80 3.4E-5 T 06-07-2017 CAK77_RS13715 30bfc4b4f9205c585918bc9f556ff36d 243 SUPERFAMILY SSF50494 36 202 1.31E-16 T 06-07-2017 IPR009003 Peptidase S1, PA clan CAK77_RS13715 30bfc4b4f9205c585918bc9f556ff36d 243 Gene3D G3DSA:2.40.10.10 122 195 9.4E-9 T 06-07-2017 CAK77_RS09950 c2b06be01d2931676355cae247c33460 106 SUPERFAMILY SSF54292 3 105 1.02E-27 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK77_RS09950 c2b06be01d2931676355cae247c33460 106 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 9 89 5.1E-13 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK77_RS09950 c2b06be01d2931676355cae247c33460 106 Gene3D G3DSA:3.10.20.30 1 102 1.1E-33 T 06-07-2017 IPR012675 Beta-grasp domain CAK77_RS03970 f58e8e38ef1b1796ad555e29a8ba5fb3 101 Gene3D G3DSA:2.60.40.1120 23 74 1.1E-6 T 06-07-2017 IPR014766 Carboxypeptidase, regulatory domain CAK77_RS03970 f58e8e38ef1b1796ad555e29a8ba5fb3 101 Pfam PF07210 Protein of unknown function (DUF1416) 2 99 1.5E-42 T 06-07-2017 IPR010814 Protein of unknown function DUF1416 CAK77_RS03970 f58e8e38ef1b1796ad555e29a8ba5fb3 101 SUPERFAMILY SSF49478 23 84 2.24E-8 T 06-07-2017 CAK77_RS22550 64955a6ea995c1b1f9862a904b8fc56b 150 Pfam PF04505 Interferon-induced transmembrane protein 34 100 1.4E-13 T 06-07-2017 IPR007593 CD225/Dispanin family GO:0009607|GO:0016021 CAK77_RS12975 96393c179b18fd454d67ae2090e8db74 61 Pfam PF13396 Phospholipase_D-nuclease N-terminal 11 53 3.4E-13 T 06-07-2017 IPR027379 Cardiolipin synthase N-terminal CAK77_RS21575 1ced2f2949dd0e607584f47cb52bfb6b 307 Pfam PF01435 Peptidase family M48 128 198 1.4E-6 T 06-07-2017 IPR001915 Peptidase M48 GO:0004222|GO:0006508 CAK77_RS21575 1ced2f2949dd0e607584f47cb52bfb6b 307 Gene3D G3DSA:3.30.2010.10 125 190 1.0E-10 T 06-07-2017 CAK77_RS02335 11640ae10bb113d06c1ad625823be3ce 320 SUPERFAMILY SSF53474 11 316 5.8E-59 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS02335 11640ae10bb113d06c1ad625823be3ce 320 Gene3D G3DSA:3.40.50.1820 10 316 1.7E-64 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS02335 11640ae10bb113d06c1ad625823be3ce 320 PRINTS PR00412 Epoxide hydrolase signature 120 133 1.3E-12 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK77_RS02335 11640ae10bb113d06c1ad625823be3ce 320 PRINTS PR00412 Epoxide hydrolase signature 134 147 1.3E-12 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK77_RS02335 11640ae10bb113d06c1ad625823be3ce 320 PRINTS PR00412 Epoxide hydrolase signature 294 316 1.3E-12 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK77_RS02335 11640ae10bb113d06c1ad625823be3ce 320 PRINTS PR00412 Epoxide hydrolase signature 261 277 1.3E-12 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK77_RS02335 11640ae10bb113d06c1ad625823be3ce 320 PRINTS PR00412 Epoxide hydrolase signature 58 76 1.3E-12 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK77_RS02335 11640ae10bb113d06c1ad625823be3ce 320 Pfam PF12697 Alpha/beta hydrolase family 54 311 2.3E-18 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS06305 04368c57c97560b405ef11fae0fd41e9 337 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 25 308 37.01 T 06-07-2017 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 CAK77_RS06305 04368c57c97560b405ef11fae0fd41e9 337 Pfam PF02401 LytB protein 27 304 2.3E-90 T 06-07-2017 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 CAK77_RS06305 04368c57c97560b405ef11fae0fd41e9 337 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 27 306 2.7E-98 T 06-07-2017 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 CAK77_RS24345 51f2393029649a8455ded2d45b72992c 238 Gene3D G3DSA:3.40.630.30 38 139 3.0E-4 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS00640 8506b4aade68fa6cb7f997e3a1948c7b 443 Pfam PF09594 Protein of unknown function (DUF2029) 76 309 4.3E-50 T 06-07-2017 IPR018584 Glycosyltransferase family 87 GO:0016758 CAK77_RS10155 6c1e384951b1ae0577fecdd56afb34a3 371 Gene3D G3DSA:3.40.1090.10 39 327 1.6E-74 T 06-07-2017 CAK77_RS10155 6c1e384951b1ae0577fecdd56afb34a3 371 SUPERFAMILY SSF52151 44 325 1.83E-55 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAK77_RS10155 6c1e384951b1ae0577fecdd56afb34a3 371 Pfam PF01734 Patatin-like phospholipase 46 227 1.6E-29 T 06-07-2017 IPR002641 Patatin/Phospholipase A2-related GO:0006629 CAK77_RS09515 70a7d0898d48694cde44b6e2f0038bb2 323 Gene3D G3DSA:3.40.1190.20 2 305 1.9E-45 T 06-07-2017 IPR029056 Ribokinase-like CAK77_RS09515 70a7d0898d48694cde44b6e2f0038bb2 323 SUPERFAMILY SSF53613 2 302 8.73E-54 T 06-07-2017 IPR029056 Ribokinase-like CAK77_RS09515 70a7d0898d48694cde44b6e2f0038bb2 323 Pfam PF00294 pfkB family carbohydrate kinase 25 295 2.5E-47 T 06-07-2017 IPR011611 Carbohydrate kinase PfkB CAK77_RS12330 984e0c7aca292a12cadd0d3786ba7537 451 Pfam PF00324 Amino acid permease 16 441 3.7E-106 T 06-07-2017 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CAK77_RS12330 984e0c7aca292a12cadd0d3786ba7537 451 PIRSF PIRSF006060 2 450 4.3E-68 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CAK77_RS12330 984e0c7aca292a12cadd0d3786ba7537 451 ProSitePatterns PS00218 Amino acid permeases signature. 41 71 - T 06-07-2017 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 CAK77_RS05275 8470f62dd1fbb5291619cc69f5c1a066 173 Gene3D G3DSA:2.60.120.10 55 170 5.4E-14 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK77_RS05275 8470f62dd1fbb5291619cc69f5c1a066 173 Gene3D G3DSA:1.10.260.40 4 54 4.1E-20 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK77_RS05275 8470f62dd1fbb5291619cc69f5c1a066 173 Pfam PF01381 Helix-turn-helix 5 57 1.7E-13 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAK77_RS05275 8470f62dd1fbb5291619cc69f5c1a066 173 Pfam PF07883 Cupin domain 106 170 4.0E-10 T 06-07-2017 IPR013096 Cupin 2, conserved barrel CAK77_RS05275 8470f62dd1fbb5291619cc69f5c1a066 173 SUPERFAMILY SSF47413 3 64 2.17E-16 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK77_RS05275 8470f62dd1fbb5291619cc69f5c1a066 173 SMART SM00530 4 59 8.7E-15 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAK77_RS05275 8470f62dd1fbb5291619cc69f5c1a066 173 SUPERFAMILY SSF51182 68 170 6.37E-19 T 06-07-2017 IPR011051 RmlC-like cupin domain CAK77_RS22630 0500d67dfd6a8f8685081000b53b3039 568 Pfam PF00171 Aldehyde dehydrogenase family 183 345 9.0E-12 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAK77_RS22630 0500d67dfd6a8f8685081000b53b3039 568 Gene3D G3DSA:3.40.605.10 10 119 2.3E-27 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAK77_RS22630 0500d67dfd6a8f8685081000b53b3039 568 Gene3D G3DSA:3.40.605.10 161 329 2.3E-27 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAK77_RS22630 0500d67dfd6a8f8685081000b53b3039 568 Gene3D G3DSA:3.40.309.10 380 464 1.6E-4 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAK77_RS22630 0500d67dfd6a8f8685081000b53b3039 568 SUPERFAMILY SSF53720 161 478 1.7E-28 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAK77_RS12350 311d3ff4c3c6f1c73dade59a68afe077 104 Gene3D G3DSA:2.60.120.10 7 89 9.7E-22 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK77_RS12350 311d3ff4c3c6f1c73dade59a68afe077 104 Pfam PF07883 Cupin domain 22 84 2.1E-19 T 06-07-2017 IPR013096 Cupin 2, conserved barrel CAK77_RS12350 311d3ff4c3c6f1c73dade59a68afe077 104 SUPERFAMILY SSF51182 12 91 4.46E-22 T 06-07-2017 IPR011051 RmlC-like cupin domain CAK77_RS18340 afdd7b46f0b23fbefe37829716c0fb8f 342 TIGRFAM TIGR00766 TIGR00766: inner membrane protein YhjD 22 290 2.2E-77 T 06-07-2017 IPR005274 Inner membrane protein YhjD CAK77_RS18340 afdd7b46f0b23fbefe37829716c0fb8f 342 Pfam PF03631 Virulence factor BrkB 35 290 3.6E-40 T 06-07-2017 IPR017039 Virulence factor BrkB CAK77_RS10685 1f9eb9beda5f33dba969ecba5aa21da8 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 22 39 1.1E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS10685 1f9eb9beda5f33dba969ecba5aa21da8 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 96 107 1.1E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS10685 1f9eb9beda5f33dba969ecba5aa21da8 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 143 159 1.1E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS10685 1f9eb9beda5f33dba969ecba5aa21da8 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 190 207 1.1E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS10685 1f9eb9beda5f33dba969ecba5aa21da8 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 188 1.1E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS10685 1f9eb9beda5f33dba969ecba5aa21da8 263 Pfam PF00106 short chain dehydrogenase 22 208 1.2E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS10685 1f9eb9beda5f33dba969ecba5aa21da8 263 Gene3D G3DSA:3.40.50.720 19 226 2.9E-33 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS10685 1f9eb9beda5f33dba969ecba5aa21da8 263 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 156 184 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK77_RS10685 1f9eb9beda5f33dba969ecba5aa21da8 263 SUPERFAMILY SSF51735 20 261 4.16E-39 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS08450 3d3e9d2d7696870646a19393c9eb5848 231 Gene3D G3DSA:3.40.50.1400 119 225 9.5E-14 T 06-07-2017 CAK77_RS08450 3d3e9d2d7696870646a19393c9eb5848 231 Gene3D G3DSA:3.40.50.1400 5 115 2.7E-22 T 06-07-2017 CAK77_RS08450 3d3e9d2d7696870646a19393c9eb5848 231 Pfam PF01903 CbiX 127 216 7.5E-7 T 06-07-2017 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 CAK77_RS08450 3d3e9d2d7696870646a19393c9eb5848 231 Pfam PF01903 CbiX 11 107 1.1E-16 T 06-07-2017 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 CAK77_RS08450 3d3e9d2d7696870646a19393c9eb5848 231 SUPERFAMILY SSF53800 6 223 6.65E-29 T 06-07-2017 CAK77_RS09800 ad845e99d2fbcdda8ed39b4f8a7ac62f 154 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 14 144 3.6E-17 T 06-07-2017 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CAK77_RS09800 ad845e99d2fbcdda8ed39b4f8a7ac62f 154 Gene3D G3DSA:3.30.530.20 4 145 8.3E-26 T 06-07-2017 IPR023393 START-like domain CAK77_RS09800 ad845e99d2fbcdda8ed39b4f8a7ac62f 154 SUPERFAMILY SSF55961 5 147 1.21E-28 T 06-07-2017 CAK77_RS10110 497eeb134ca97df66e32a9cd48cad480 136 SUPERFAMILY SSF55718 27 113 2.35E-10 T 06-07-2017 IPR003033 SCP2 sterol-binding domain CAK77_RS10110 497eeb134ca97df66e32a9cd48cad480 136 Gene3D G3DSA:3.30.1050.10 34 116 7.5E-10 T 06-07-2017 IPR003033 SCP2 sterol-binding domain CAK77_RS09570 39c218fd669e3ad327332f1f14a6bc59 206 Gene3D G3DSA:1.20.120.80 26 205 2.8E-55 T 06-07-2017 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK77_RS09570 39c218fd669e3ad327332f1f14a6bc59 206 SUPERFAMILY SSF81452 13 204 5.49E-57 T 06-07-2017 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK77_RS09570 39c218fd669e3ad327332f1f14a6bc59 206 Pfam PF00510 Cytochrome c oxidase subunit III 22 204 1.3E-28 T 06-07-2017 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK77_RS00505 527e645910403187139d315dd46a0c2e 128 Pfam PF06993 Protein of unknown function (DUF1304) 11 123 1.7E-35 T 06-07-2017 IPR009732 Protein of unknown function DUF1304 CAK77_RS20735 d406083516a5428cb35934b9ec58f9f9 177 Pfam PF04978 Protein of unknown function (DUF664) 16 174 4.3E-24 T 06-07-2017 IPR007061 Protein of unknown function DUF664 CAK77_RS20735 d406083516a5428cb35934b9ec58f9f9 177 SUPERFAMILY SSF109854 6 173 3.36E-31 T 06-07-2017 CAK77_RS20735 d406083516a5428cb35934b9ec58f9f9 177 Gene3D G3DSA:1.20.120.450 11 174 1.1E-66 T 06-07-2017 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase CAK77_RS15610 e8694f11e000d9442fa384f4041cc57c 162 SUPERFAMILY SSF55961 23 150 2.75E-7 T 06-07-2017 CAK77_RS15610 e8694f11e000d9442fa384f4041cc57c 162 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 24 154 6.7E-7 T 06-07-2017 IPR019587 Polyketide cyclase/dehydrase CAK77_RS23395 3c45d125d859bb3026c0a827ad932ea9 259 Pfam PF11139 Sap, sulfolipid-1-addressing protein 5 258 4.0E-55 T 06-07-2017 IPR021315 Glycolipid exporter Gap/Sap CAK77_RS12215 c85f796c1960c51d08a983c948f22dce 140 Gene3D G3DSA:3.30.750.24 38 120 7.8E-14 T 06-07-2017 IPR002645 STAS domain CAK77_RS12215 c85f796c1960c51d08a983c948f22dce 140 Pfam PF01740 STAS domain 38 106 7.1E-9 T 06-07-2017 IPR002645 STAS domain CAK77_RS12215 c85f796c1960c51d08a983c948f22dce 140 SUPERFAMILY SSF52091 36 127 2.16E-12 T 06-07-2017 IPR002645 STAS domain CAK77_RS22415 4a17109679fcde74cb1a7e64dbe54370 229 Pfam PF01936 NYN domain 26 188 1.6E-5 T 06-07-2017 IPR021139 NYN domain, limkain-b1-type CAK77_RS22415 4a17109679fcde74cb1a7e64dbe54370 229 Gene3D G3DSA:3.40.50.1010 25 193 1.7E-7 T 06-07-2017 IPR029060 PIN domain-like CAK77_RS24440 718a88ddb819d6bdd225f00550d62b2c 342 Pfam PF01909 Nucleotidyltransferase domain 46 76 6.8E-5 T 06-07-2017 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 CAK77_RS24440 718a88ddb819d6bdd225f00550d62b2c 342 SUPERFAMILY SSF81301 39 87 1.56E-7 T 06-07-2017 CAK77_RS24440 718a88ddb819d6bdd225f00550d62b2c 342 Gene3D G3DSA:3.30.460.10 45 83 5.7E-8 T 06-07-2017 CAK77_RS18575 b09641f27471029026c2974cb83b644b 443 Gene3D G3DSA:3.40.390.10 291 434 5.2E-10 T 06-07-2017 IPR024079 Metallopeptidase, catalytic domain GO:0008237 CAK77_RS18575 b09641f27471029026c2974cb83b644b 443 SUPERFAMILY SSF55486 295 442 6.36E-13 T 06-07-2017 CAK77_RS11870 37d914fcd0ba6503fa2df0cd450b20ed 267 SUPERFAMILY SSF109604 88 180 8.57E-14 T 06-07-2017 CAK77_RS11870 37d914fcd0ba6503fa2df0cd450b20ed 267 Gene3D G3DSA:1.10.3210.10 87 185 2.8E-10 T 06-07-2017 IPR006674 HD domain CAK77_RS06345 ba3a24d0ef20088e7c74300259c6345f 115 Pfam PF04343 Protein of unknown function, DUF488 5 113 3.0E-29 T 06-07-2017 IPR007438 Protein of unknown function DUF488 CAK77_RS18550 7a1b7368ba2565d5b2182ee417688891 96 Pfam PF02467 Transcription factor WhiB 17 85 9.7E-23 T 06-07-2017 IPR003482 Transcription factor WhiB CAK77_RS18550 7a1b7368ba2565d5b2182ee417688891 96 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 92 19.559 T 06-07-2017 IPR003482 Transcription factor WhiB CAK77_RS16525 cf81b42ca74a845be4552c1a9f7f4319 130 ProDom PD072817 ANTIGEN WEIGHT MOLECULAR LOW CFP-6 CGL1269 SEQUENCING DIRECT 14 125 3.0E-22 T 06-07-2017 IPR020535 Low molecular weight antigen Cfp6 CAK77_RS16525 cf81b42ca74a845be4552c1a9f7f4319 130 Pfam PF10756 Bacterial PH domain 52 122 5.3E-14 T 06-07-2017 IPR019692 Protein of unknown function DUF2581 CAK77_RS03040 0e77032e589e7e9aa8913ae43c6c536d 193 SUPERFAMILY SSF50475 6 165 6.38E-48 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS03040 0e77032e589e7e9aa8913ae43c6c536d 193 Pfam PF01613 Flavin reductase like domain 16 166 5.3E-36 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 CAK77_RS03040 0e77032e589e7e9aa8913ae43c6c536d 193 Gene3D G3DSA:2.30.110.10 3 163 4.7E-57 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS03040 0e77032e589e7e9aa8913ae43c6c536d 193 SMART SM00903 15 165 1.4E-55 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 CAK77_RS19200 58fd39e54ff8eafb9364fb5bc41aa29e 449 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 152 333 5.7E-17 T 06-07-2017 IPR018713 Domain of unknown function DUF2236 CAK77_RS20085 8684568f4872eb986c19b4603fa45abd 151 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 38 149 3.2E-25 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CAK77_RS20085 8684568f4872eb986c19b4603fa45abd 151 Pfam PF04075 Domain of unknown function (DUF385) 29 150 2.4E-29 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CAK77_RS09705 2e004100d448671b1a6619ded8e6c389 134 Pfam PF11239 Protein of unknown function (DUF3040) 1 86 1.6E-29 T 06-07-2017 IPR021401 Protein of unknown function DUF3040 CAK77_RS23270 39ce0368e65d35cee56da4ccbbd69368 385 SUPERFAMILY SSF56801 79 344 6.41E-8 T 06-07-2017 CAK77_RS23270 39ce0368e65d35cee56da4ccbbd69368 385 Pfam PF04443 Acyl-protein synthetase, LuxE 25 361 5.2E-40 T 06-07-2017 IPR007534 Acyl-protein synthetase, LuxE GO:0008218|GO:0047474 MetaCyc: PWY-7723 CAK77_RS05305 6d86ebd03e0c6e2e4255c5d8aff70bd5 323 SUPERFAMILY SSF51261 185 311 1.44E-49 T 06-07-2017 IPR011055 Duplicated hybrid motif CAK77_RS05305 6d86ebd03e0c6e2e4255c5d8aff70bd5 323 Pfam PF01551 Peptidase family M23 213 307 1.4E-30 T 06-07-2017 IPR016047 Peptidase M23 CAK77_RS05305 6d86ebd03e0c6e2e4255c5d8aff70bd5 323 Gene3D G3DSA:2.70.70.10 173 312 1.2E-45 T 06-07-2017 CAK77_RS22545 d04c0723042baa590274809715835359 173 Pfam PF01381 Helix-turn-helix 121 159 3.7E-5 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAK77_RS22545 d04c0723042baa590274809715835359 173 SUPERFAMILY SSF47413 107 159 1.87E-5 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK77_RS22545 d04c0723042baa590274809715835359 173 Gene3D G3DSA:1.10.260.40 113 160 3.7E-6 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK77_RS16620 2e17a432766502ae4112816ca71a5987 102 SUPERFAMILY SSF141000 4 97 1.06E-23 T 06-07-2017 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CAK77_RS16620 2e17a432766502ae4112816ca71a5987 102 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 3 99 22.033 T 06-07-2017 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CAK77_RS16620 2e17a432766502ae4112816ca71a5987 102 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 20 94 4.8E-14 T 06-07-2017 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CAK77_RS16620 2e17a432766502ae4112816ca71a5987 102 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 4 98 2.5E-23 T 06-07-2017 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CAK77_RS19275 5e0776547aece3ab931919f9a591d903 113 SUPERFAMILY SSF46785 5 102 2.79E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS19275 5e0776547aece3ab931919f9a591d903 113 Pfam PF12840 Helix-turn-helix domain 12 69 1.6E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS19275 5e0776547aece3ab931919f9a591d903 113 SMART SM00418 11 89 2.7E-14 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAK77_RS19275 5e0776547aece3ab931919f9a591d903 113 Gene3D G3DSA:1.10.10.10 4 108 1.1E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS06735 69b7aa9e4353c818fd33114011fe551d 110 Pfam PF14279 HNH endonuclease 39 79 6.5E-8 T 06-07-2017 IPR029471 HNH endonuclease 5 CAK77_RS06735 69b7aa9e4353c818fd33114011fe551d 110 SMART SM00507 27 77 6.1E-6 T 06-07-2017 IPR003615 HNH nuclease CAK77_RS22320 ea28b6eddcb91369c5a749cb71d2a14b 386 Pfam PF01636 Phosphotransferase enzyme family 95 289 1.1E-16 T 06-07-2017 IPR002575 Aminoglycoside phosphotransferase CAK77_RS22320 ea28b6eddcb91369c5a749cb71d2a14b 386 Gene3D G3DSA:3.90.1200.10 159 356 7.5E-20 T 06-07-2017 CAK77_RS22320 ea28b6eddcb91369c5a749cb71d2a14b 386 SUPERFAMILY SSF56112 51 353 1.14E-29 T 06-07-2017 IPR011009 Protein kinase-like domain CAK77_RS21325 bdbf06e2489743275ff5cb5c1d5e94ee 245 Pfam PF07103 Protein of unknown function (DUF1365) 10 236 5.5E-55 T 06-07-2017 IPR010775 Protein of unknown function DUF1365 CAK77_RS00315 575954df53f29ab4d7893a877f927386 238 Pfam PF05949 Bacterial protein of unknown function (DUF881) 82 226 6.0E-36 T 06-07-2017 IPR010273 Protein of unknown function DUF881 CAK77_RS07555 302eef6e1120771114a1063d911d7f92 345 SUPERFAMILY SSF53850 37 332 1.19E-44 T 06-07-2017 CAK77_RS07555 302eef6e1120771114a1063d911d7f92 345 Gene3D G3DSA:3.40.190.10 136 272 6.3E-22 T 06-07-2017 CAK77_RS07555 302eef6e1120771114a1063d911d7f92 345 Pfam PF13531 Bacterial extracellular solute-binding protein 37 289 2.5E-20 T 06-07-2017 CAK77_RS07555 302eef6e1120771114a1063d911d7f92 345 Gene3D G3DSA:3.40.190.10 9 130 2.4E-26 T 06-07-2017 CAK77_RS07555 302eef6e1120771114a1063d911d7f92 345 Gene3D G3DSA:3.40.190.10 273 315 2.4E-26 T 06-07-2017 CAK77_RS18645 6f9a43a3babdaf8661a772e178de9e52 363 Gene3D G3DSA:3.40.50.1820 54 344 1.5E-51 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS18645 6f9a43a3babdaf8661a772e178de9e52 363 SUPERFAMILY SSF53474 54 340 6.2E-48 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS18645 6f9a43a3babdaf8661a772e178de9e52 363 Pfam PF12697 Alpha/beta hydrolase family 77 335 8.6E-21 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS06220 026bda18c8dfb572f1520adaa853d80b 288 Pfam PF01522 Polysaccharide deacetylase 42 159 8.2E-33 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAK77_RS06220 026bda18c8dfb572f1520adaa853d80b 288 Gene3D G3DSA:3.20.20.370 36 228 2.4E-58 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAK77_RS06220 026bda18c8dfb572f1520adaa853d80b 288 SUPERFAMILY SSF88713 40 228 1.17E-58 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CAK77_RS04205 0ec5f15dabb75e110b484e8359288747 296 Gene3D G3DSA:3.40.50.1820 47 291 1.5E-75 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS04205 0ec5f15dabb75e110b484e8359288747 296 Pfam PF07859 alpha/beta hydrolase fold 71 270 6.7E-64 T 06-07-2017 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CAK77_RS04205 0ec5f15dabb75e110b484e8359288747 296 SUPERFAMILY SSF53474 51 292 1.58E-60 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS03885 0bc64f7969f27af06c48ae948736b49c 209 Gene3D G3DSA:3.40.50.1820 123 209 1.3E-11 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS03885 0bc64f7969f27af06c48ae948736b49c 209 SUPERFAMILY SSF53474 126 208 3.56E-6 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS22600 7580a7944133866acc5c35c6b1427627 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 38 7.5E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS22600 7580a7944133866acc5c35c6b1427627 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 7.5E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS22600 7580a7944133866acc5c35c6b1427627 200 Gene3D G3DSA:1.10.10.60 12 70 9.9E-20 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS22600 7580a7944133866acc5c35c6b1427627 200 SUPERFAMILY SSF48498 92 180 3.52E-8 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS22600 7580a7944133866acc5c35c6b1427627 200 SUPERFAMILY SSF46689 12 96 8.21E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS22600 7580a7944133866acc5c35c6b1427627 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 69 8.9E-15 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS22600 7580a7944133866acc5c35c6b1427627 200 Gene3D G3DSA:1.10.357.10 71 194 1.3E-25 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS12505 4adeef8f8ef9d98e8cc5b288adb66439 239 Pfam PF01988 VIT family 24 231 1.3E-54 T 06-07-2017 IPR008217 Ccc1 family CAK77_RS13350 fec20066d6edd179683df31fb8600f66 323 Pfam PF01882 Protein of unknown function DUF58 58 140 4.6E-19 T 06-07-2017 IPR002881 Domain of unknown function DUF58 CAK77_RS19875 bf5082c63ac527e0ee74aa263de4bbb0 490 Pfam PF13450 NAD(P)-binding Rossmann-like domain 13 65 1.9E-8 T 06-07-2017 CAK77_RS19875 bf5082c63ac527e0ee74aa263de4bbb0 490 SUPERFAMILY SSF51905 179 218 1.68E-10 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS19875 bf5082c63ac527e0ee74aa263de4bbb0 490 SUPERFAMILY SSF51905 304 389 1.68E-10 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS19875 bf5082c63ac527e0ee74aa263de4bbb0 490 SUPERFAMILY SSF51905 6 216 2.09E-48 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS19875 bf5082c63ac527e0ee74aa263de4bbb0 490 Gene3D G3DSA:3.50.50.60 4 217 4.4E-52 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS19875 bf5082c63ac527e0ee74aa263de4bbb0 490 Gene3D G3DSA:3.50.50.60 327 466 4.8E-4 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS19875 bf5082c63ac527e0ee74aa263de4bbb0 490 Pfam PF00743 Flavin-binding monooxygenase-like 80 225 8.6E-15 T 06-07-2017 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 CAK77_RS02985 e4088beed14e4f9524be34ad072855a8 276 Pfam PF00950 ABC 3 transport family 17 267 2.1E-45 T 06-07-2017 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 CAK77_RS02985 e4088beed14e4f9524be34ad072855a8 276 SUPERFAMILY SSF81345 10 266 4.45E-31 T 06-07-2017 IPR029022 ABC transporter, BtuC-like CAK77_RS08810 1e98b614878f4ef983c5006736de807a 278 Gene3D G3DSA:3.90.640.20 236 277 7.3E-6 T 06-07-2017 IPR021729 Domain of unknown function DUF3298 CAK77_RS08810 1e98b614878f4ef983c5006736de807a 278 Pfam PF11738 Protein of unknown function (DUF3298) 167 271 4.4E-9 T 06-07-2017 IPR021729 Domain of unknown function DUF3298 CAK77_RS00265 eb39a8ccf8a6b6961c5fca0952570db3 85 Gene3D G3DSA:1.10.260.40 15 84 3.9E-16 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK77_RS00265 eb39a8ccf8a6b6961c5fca0952570db3 85 SUPERFAMILY SSF47413 17 83 4.29E-15 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK77_RS00265 eb39a8ccf8a6b6961c5fca0952570db3 85 Pfam PF01381 Helix-turn-helix 27 78 5.9E-11 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAK77_RS00265 eb39a8ccf8a6b6961c5fca0952570db3 85 SMART SM00530 26 81 1.8E-11 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAK77_RS19705 ba0010e351176887c9100447643ee28a 278 PRINTS PR00412 Epoxide hydrolase signature 215 231 1.6E-6 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK77_RS19705 ba0010e351176887c9100447643ee28a 278 PRINTS PR00412 Epoxide hydrolase signature 53 68 1.6E-6 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK77_RS19705 ba0010e351176887c9100447643ee28a 278 PRINTS PR00412 Epoxide hydrolase signature 97 110 1.6E-6 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK77_RS19705 ba0010e351176887c9100447643ee28a 278 PRINTS PR00412 Epoxide hydrolase signature 111 124 1.6E-6 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK77_RS19705 ba0010e351176887c9100447643ee28a 278 PRINTS PR00412 Epoxide hydrolase signature 248 270 1.6E-6 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK77_RS19705 ba0010e351176887c9100447643ee28a 278 Gene3D G3DSA:3.40.50.1820 5 273 1.4E-57 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS19705 ba0010e351176887c9100447643ee28a 278 Pfam PF12697 Alpha/beta hydrolase family 28 265 1.7E-20 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS19705 ba0010e351176887c9100447643ee28a 278 SUPERFAMILY SSF53474 3 273 4.41E-57 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS03825 902f7b05bb559fe3cc94e4e8c92a79fe 177 Gene3D G3DSA:1.10.3210.10 14 112 9.2E-11 T 06-07-2017 IPR006674 HD domain CAK77_RS03825 902f7b05bb559fe3cc94e4e8c92a79fe 177 SUPERFAMILY SSF109604 22 95 5.56E-13 T 06-07-2017 CAK77_RS03825 902f7b05bb559fe3cc94e4e8c92a79fe 177 Pfam PF01966 HD domain 22 100 9.2E-9 T 06-07-2017 IPR006674 HD domain CAK77_RS20270 ac1e2e7e18ca7c38c417bec70e288619 442 SUPERFAMILY SSF48498 328 438 7.91E-5 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS20270 ac1e2e7e18ca7c38c417bec70e288619 442 Gene3D G3DSA:1.10.357.10 24 218 2.3E-30 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS20270 ac1e2e7e18ca7c38c417bec70e288619 442 Pfam PF00440 Bacterial regulatory proteins, tetR family 28 72 1.4E-13 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS20270 ac1e2e7e18ca7c38c417bec70e288619 442 Pfam PF00440 Bacterial regulatory proteins, tetR family 254 300 4.3E-15 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS20270 ac1e2e7e18ca7c38c417bec70e288619 442 SUPERFAMILY SSF46689 247 312 2.67E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS20270 ac1e2e7e18ca7c38c417bec70e288619 442 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 49 72 2.9E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS20270 ac1e2e7e18ca7c38c417bec70e288619 442 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 41 2.9E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS20270 ac1e2e7e18ca7c38c417bec70e288619 442 SUPERFAMILY SSF46689 20 86 9.48E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS20270 ac1e2e7e18ca7c38c417bec70e288619 442 Gene3D G3DSA:1.10.357.10 249 438 3.0E-33 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS12785 9cf41f9e554395ebae2cd1b0e01ecaea 419 Pfam PF13520 Amino acid permease 13 389 4.0E-45 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CAK77_RS12785 9cf41f9e554395ebae2cd1b0e01ecaea 419 PIRSF PIRSF006060 1 413 1.9E-73 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CAK77_RS20630 34d42ccf394439f444b783a1c38f85f9 959 SUPERFAMILY SSF82866 723 932 2.22E-30 T 06-07-2017 CAK77_RS20630 34d42ccf394439f444b783a1c38f85f9 959 TIGRFAM TIGR00833 actII: transport protein 22 932 0.0 T 06-07-2017 IPR004707 Membrane transport protein MmpL family GO:0016021 CAK77_RS20630 34d42ccf394439f444b783a1c38f85f9 959 SUPERFAMILY SSF82866 151 351 8.24E-30 T 06-07-2017 CAK77_RS20630 34d42ccf394439f444b783a1c38f85f9 959 Pfam PF03176 MMPL family 606 940 7.6E-101 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 CAK77_RS20630 34d42ccf394439f444b783a1c38f85f9 959 Pfam PF03176 MMPL family 54 384 8.2E-111 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 CAK77_RS20630 34d42ccf394439f444b783a1c38f85f9 959 Gene3D G3DSA:1.20.1640.10 150 355 2.3E-29 T 06-07-2017 CAK77_RS20630 34d42ccf394439f444b783a1c38f85f9 959 Gene3D G3DSA:1.20.1640.10 735 932 5.4E-25 T 06-07-2017 CAK77_RS00235 fb5124d151f13902f6bd7dcb849a0889 132 Gene3D G3DSA:3.30.70.900 11 102 4.4E-11 T 06-07-2017 CAK77_RS00235 fb5124d151f13902f6bd7dcb849a0889 132 SUPERFAMILY SSF54909 11 87 4.54E-12 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAK77_RS12390 1777f17fd9941afd064762f96bafccdd 70 Pfam PF03459 TOBE domain 4 66 5.6E-15 T 06-07-2017 IPR005116 Transport-associated OB, type 1 CAK77_RS12390 1777f17fd9941afd064762f96bafccdd 70 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 1 69 8.1E-19 T 06-07-2017 IPR004606 Molybdenum-pterin binding GO:0006810|GO:0030151 CAK77_RS12390 1777f17fd9941afd064762f96bafccdd 70 Gene3D G3DSA:2.40.50.100 1 68 7.9E-23 T 06-07-2017 CAK77_RS12390 1777f17fd9941afd064762f96bafccdd 70 SUPERFAMILY SSF50331 1 69 1.43E-19 T 06-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal CAK77_RS03620 d934b28dbf7ef360ea346a27984164c2 265 Pfam PF04454 Encapsulating protein for peroxidase 1 251 1.5E-96 T 06-07-2017 IPR007544 Encapsulating protein for peroxidase GO:0008233|GO:0042742 CAK77_RS03620 d934b28dbf7ef360ea346a27984164c2 265 PIRSF PIRSF019254 1 264 2.8E-90 T 06-07-2017 IPR007544 Encapsulating protein for peroxidase GO:0008233|GO:0042742 CAK77_RS07120 10231ab39927883729c0a261bdd1a634 874 Gene3D G3DSA:3.40.50.300 238 294 2.3E-17 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS07120 10231ab39927883729c0a261bdd1a634 874 Gene3D G3DSA:3.40.50.300 2 94 2.3E-17 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS07120 10231ab39927883729c0a261bdd1a634 874 Gene3D G3DSA:3.40.50.300 529 545 2.3E-17 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS07120 10231ab39927883729c0a261bdd1a634 874 Gene3D G3DSA:3.40.50.300 752 864 2.3E-17 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS07120 10231ab39927883729c0a261bdd1a634 874 Pfam PF13175 AAA ATPase domain 2 64 3.5E-8 T 06-07-2017 CAK77_RS07120 10231ab39927883729c0a261bdd1a634 874 SUPERFAMILY SSF52540 745 864 3.38E-19 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS07120 10231ab39927883729c0a261bdd1a634 874 SUPERFAMILY SSF52540 192 228 3.38E-19 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS07120 10231ab39927883729c0a261bdd1a634 874 SUPERFAMILY SSF52540 2 137 3.38E-19 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS06725 fc52c4940ac15b8ba327143eda82c05f 182 Pfam PF03641 Possible lysine decarboxylase 48 176 6.4E-37 T 06-07-2017 IPR031100 LOG family CAK77_RS06725 fc52c4940ac15b8ba327143eda82c05f 182 Gene3D G3DSA:3.40.50.450 6 178 8.7E-55 T 06-07-2017 CAK77_RS06725 fc52c4940ac15b8ba327143eda82c05f 182 SUPERFAMILY SSF102405 3 177 1.28E-53 T 06-07-2017 CAK77_RS06725 fc52c4940ac15b8ba327143eda82c05f 182 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 6 179 1.9E-60 T 06-07-2017 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG CAK77_RS09350 e2ef1d8d1590a80bb7a3285d475e3b6c 318 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 108 305 3.6E-19 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase CAK77_RS09350 e2ef1d8d1590a80bb7a3285d475e3b6c 318 SUPERFAMILY SSF56219 92 312 6.02E-23 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase CAK77_RS09350 e2ef1d8d1590a80bb7a3285d475e3b6c 318 Gene3D G3DSA:3.60.10.10 105 311 1.5E-6 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase CAK77_RS13645 831531094db6a76cf41204da8b1522b5 475 TIGRFAM TIGR00908 2A0305: ethanolamine permease 21 463 1.1E-158 T 06-07-2017 IPR004757 Ethanolamine permease CAK77_RS13645 831531094db6a76cf41204da8b1522b5 475 Pfam PF13520 Amino acid permease 32 431 3.2E-40 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CAK77_RS13645 831531094db6a76cf41204da8b1522b5 475 PIRSF PIRSF006060 12 473 6.2E-60 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CAK77_RS19670 9a37e645e9eb9226ed419a186e35194b 289 Hamap MF_00188 Protease HtpX [htpX]. 10 286 26.872 T 06-07-2017 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 CAK77_RS19670 9a37e645e9eb9226ed419a186e35194b 289 Pfam PF01435 Peptidase family M48 71 286 6.1E-36 T 06-07-2017 IPR001915 Peptidase M48 GO:0004222|GO:0006508 CAK77_RS19670 9a37e645e9eb9226ed419a186e35194b 289 Gene3D G3DSA:3.30.2010.10 63 153 7.2E-32 T 06-07-2017 CAK77_RS24260 63e693c419024853b4d753dc90257848 399 SUPERFAMILY SSF52777 29 144 1.09E-10 T 06-07-2017 CAK77_RS24260 63e693c419024853b4d753dc90257848 399 Pfam PF16911 Phthiocerol/phthiodiolone dimycocerosyl transferase C-terminus 278 383 6.0E-18 T 06-07-2017 IPR031641 Phthiocerol/phthiodiolone dimycocerosyl transferase, C-terminal CAK77_RS24260 63e693c419024853b4d753dc90257848 399 SUPERFAMILY SSF52777 158 372 6.78E-27 T 06-07-2017 CAK77_RS11760 455e6c20a72c0bd2ede259837fd34507 251 Pfam PF14032 PknH-like extracellular domain 66 247 1.1E-30 T 06-07-2017 IPR026954 PknH-like extracellular domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 CAK77_RS17210 eae2899cdacdeeed2b046deee5ad4d78 506 Pfam PF00135 Carboxylesterase family 11 493 3.6E-98 T 06-07-2017 IPR002018 Carboxylesterase, type B CAK77_RS17210 eae2899cdacdeeed2b046deee5ad4d78 506 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 185 200 - T 06-07-2017 IPR019826 Carboxylesterase type B, active site CAK77_RS17210 eae2899cdacdeeed2b046deee5ad4d78 506 SUPERFAMILY SSF53474 9 502 1.93E-116 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS17210 eae2899cdacdeeed2b046deee5ad4d78 506 Gene3D G3DSA:3.40.50.1820 6 501 2.7E-132 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS17210 eae2899cdacdeeed2b046deee5ad4d78 506 ProSitePatterns PS00941 Carboxylesterases type-B signature 2. 86 96 - T 06-07-2017 IPR019819 Carboxylesterase type B, conserved site CAK77_RS16070 9953d4524f7d1fd2fdff90be58715c4e 148 Pfam PF13577 SnoaL-like domain 9 138 9.7E-25 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain CAK77_RS16070 9953d4524f7d1fd2fdff90be58715c4e 148 SUPERFAMILY SSF54427 6 146 1.05E-30 T 06-07-2017 IPR032710 NTF2-like domain CAK77_RS16070 9953d4524f7d1fd2fdff90be58715c4e 148 Gene3D G3DSA:3.10.450.50 10 145 1.4E-35 T 06-07-2017 IPR032710 NTF2-like domain CAK77_RS17050 e9b02afaaa61a57f7ea3819c77e09178 291 Pfam PF14257 Domain of unknown function (DUF4349) 5 264 2.2E-68 T 06-07-2017 IPR025645 Domain of unknown function DUF4349 CAK77_RS10040 bba16ab24f0eb6c62533dfd3a12a60f4 203 Gene3D G3DSA:1.10.357.10 2 161 1.9E-22 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS10040 bba16ab24f0eb6c62533dfd3a12a60f4 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 2 48 6.8E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS10040 bba16ab24f0eb6c62533dfd3a12a60f4 203 SUPERFAMILY SSF46689 2 65 2.31E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS13330 5123363ee0d7c9f7e7d177965feae9c1 340 ProSitePatterns PS00534 Ferrochelatase signature. 172 192 - T 06-07-2017 IPR019772 Ferrochelatase, active site GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 CAK77_RS13330 5123363ee0d7c9f7e7d177965feae9c1 340 Gene3D G3DSA:3.40.50.1400 4 154 2.2E-38 T 06-07-2017 CAK77_RS13330 5123363ee0d7c9f7e7d177965feae9c1 340 Gene3D G3DSA:3.40.50.1400 155 285 1.3E-43 T 06-07-2017 CAK77_RS13330 5123363ee0d7c9f7e7d177965feae9c1 340 Pfam PF00762 Ferrochelatase 4 302 2.7E-94 T 06-07-2017 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 CAK77_RS13330 5123363ee0d7c9f7e7d177965feae9c1 340 Hamap MF_00323 Ferrochelatase [hemH]. 2 304 29.754 T 06-07-2017 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 CAK77_RS13330 5123363ee0d7c9f7e7d177965feae9c1 340 SUPERFAMILY SSF53800 4 327 3.27E-81 T 06-07-2017 CAK77_RS13330 5123363ee0d7c9f7e7d177965feae9c1 340 TIGRFAM TIGR00109 hemH: ferrochelatase 5 301 2.1E-37 T 06-07-2017 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 CAK77_RS22150 f71636f612d00fd2d23f7f294ff6eeb4 497 SUPERFAMILY SSF81296 386 495 4.62E-22 T 06-07-2017 IPR014756 Immunoglobulin E-set CAK77_RS22150 f71636f612d00fd2d23f7f294ff6eeb4 497 Pfam PF00174 Oxidoreductase molybdopterin binding domain 222 369 1.2E-36 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CAK77_RS22150 f71636f612d00fd2d23f7f294ff6eeb4 497 Gene3D G3DSA:3.90.420.10 207 389 2.9E-47 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CAK77_RS22150 f71636f612d00fd2d23f7f294ff6eeb4 497 Gene3D G3DSA:2.60.40.650 390 478 3.0E-16 T 06-07-2017 IPR005066 Moybdenum cofactor oxidoreductase, dimerisation GO:0016491|GO:0030151|GO:0055114 Reactome: R-HSA-1614517 CAK77_RS22150 f71636f612d00fd2d23f7f294ff6eeb4 497 SUPERFAMILY SSF56524 209 386 9.03E-49 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CAK77_RS05170 3ebcbdfc0962246bc16cb028e09ed89f 329 Pfam PF15599 Immunity protein 63 243 326 2.1E-24 T 06-07-2017 IPR028952 Immunity protein 63 CAK77_RS14060 de11d9e5446d6526abb5dfe0b45e820e 307 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 141 304 1.1E-26 T 06-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CAK77_RS14060 de11d9e5446d6526abb5dfe0b45e820e 307 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 232 247 2.6E-6 T 06-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CAK77_RS14060 de11d9e5446d6526abb5dfe0b45e820e 307 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 153 168 2.6E-6 T 06-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CAK77_RS14060 de11d9e5446d6526abb5dfe0b45e820e 307 Gene3D G3DSA:2.40.100.10 138 304 2.3E-35 T 06-07-2017 IPR029000 Cyclophilin-like domain CAK77_RS14060 de11d9e5446d6526abb5dfe0b45e820e 307 SUPERFAMILY SSF50891 131 303 4.38E-36 T 06-07-2017 IPR029000 Cyclophilin-like domain CAK77_RS19850 3ceb37b9d16d6c7f727d43e815f6994d 467 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 406 415 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CAK77_RS19850 3ceb37b9d16d6c7f727d43e815f6994d 467 PRINTS PR00385 P450 superfamily signature 329 340 3.8E-10 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS19850 3ceb37b9d16d6c7f727d43e815f6994d 467 PRINTS PR00385 P450 superfamily signature 276 293 3.8E-10 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS19850 3ceb37b9d16d6c7f727d43e815f6994d 467 PRINTS PR00385 P450 superfamily signature 413 424 3.8E-10 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS19850 3ceb37b9d16d6c7f727d43e815f6994d 467 PRINTS PR00385 P450 superfamily signature 404 413 3.8E-10 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS19850 3ceb37b9d16d6c7f727d43e815f6994d 467 SUPERFAMILY SSF48264 27 467 6.55E-71 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS19850 3ceb37b9d16d6c7f727d43e815f6994d 467 Gene3D G3DSA:1.10.630.10 30 463 8.8E-69 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS19850 3ceb37b9d16d6c7f727d43e815f6994d 467 Pfam PF00067 Cytochrome P450 46 440 5.6E-46 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS19850 3ceb37b9d16d6c7f727d43e815f6994d 467 PRINTS PR00465 E-class P450 group IV signature 413 431 5.5E-15 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS19850 3ceb37b9d16d6c7f727d43e815f6994d 467 PRINTS PR00465 E-class P450 group IV signature 324 340 5.5E-15 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS19850 3ceb37b9d16d6c7f727d43e815f6994d 467 PRINTS PR00465 E-class P450 group IV signature 373 391 5.5E-15 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS19850 3ceb37b9d16d6c7f727d43e815f6994d 467 PRINTS PR00465 E-class P450 group IV signature 397 413 5.5E-15 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS19850 3ceb37b9d16d6c7f727d43e815f6994d 467 PRINTS PR00465 E-class P450 group IV signature 46 69 5.5E-15 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAK77_RS23710 b4503d8547709ae9cdcf2045445d6594 237 SUPERFAMILY SSF55469 1 63 3.4E-40 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CAK77_RS23710 b4503d8547709ae9cdcf2045445d6594 237 SUPERFAMILY SSF55469 102 221 3.4E-40 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CAK77_RS23710 b4503d8547709ae9cdcf2045445d6594 237 Pfam PF00881 Nitroreductase family 12 191 1.1E-23 T 06-07-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 CAK77_RS23710 b4503d8547709ae9cdcf2045445d6594 237 Gene3D G3DSA:3.40.109.10 1 231 2.5E-41 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CAK77_RS15495 f5e7df4474b1d9eec6388d0c010c9752 219 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 107 189 4.1E-12 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CAK77_RS15495 f5e7df4474b1d9eec6388d0c010c9752 219 SUPERFAMILY SSF56214 105 217 4.53E-15 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CAK77_RS15495 f5e7df4474b1d9eec6388d0c010c9752 219 Gene3D G3DSA:3.90.470.20 120 186 6.0E-5 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CAK77_RS15495 f5e7df4474b1d9eec6388d0c010c9752 219 PRINTS PR01399 Enterobactin synthetase component D signature 73 91 3.7E-25 T 06-07-2017 IPR003542 Enterobactin synthetase-like, component D GO:0009239|GO:0009366|GO:0016780 CAK77_RS15495 f5e7df4474b1d9eec6388d0c010c9752 219 PRINTS PR01399 Enterobactin synthetase component D signature 147 163 3.7E-25 T 06-07-2017 IPR003542 Enterobactin synthetase-like, component D GO:0009239|GO:0009366|GO:0016780 CAK77_RS15495 f5e7df4474b1d9eec6388d0c010c9752 219 PRINTS PR01399 Enterobactin synthetase component D signature 43 63 3.7E-25 T 06-07-2017 IPR003542 Enterobactin synthetase-like, component D GO:0009239|GO:0009366|GO:0016780 CAK77_RS05585 ee56669dcd1480c9023d3dfbbd270ee8 385 Gene3D G3DSA:3.50.50.60 5 155 5.7E-28 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS05585 ee56669dcd1480c9023d3dfbbd270ee8 385 Gene3D G3DSA:3.50.50.60 156 291 1.3E-17 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS05585 ee56669dcd1480c9023d3dfbbd270ee8 385 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 284 2.9E-44 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS05585 ee56669dcd1480c9023d3dfbbd270ee8 385 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 248 270 4.9E-11 T 06-07-2017 CAK77_RS05585 ee56669dcd1480c9023d3dfbbd270ee8 385 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 142 160 4.9E-11 T 06-07-2017 CAK77_RS05585 ee56669dcd1480c9023d3dfbbd270ee8 385 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 4.9E-11 T 06-07-2017 CAK77_RS05585 ee56669dcd1480c9023d3dfbbd270ee8 385 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 95 113 4.9E-11 T 06-07-2017 CAK77_RS05585 ee56669dcd1480c9023d3dfbbd270ee8 385 SUPERFAMILY SSF51905 1 292 2.99E-31 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS17540 bc58f97cef4ba1a026eb9fedb416ee19 138 Pfam PF04134 Protein of unknown function, DUF393 8 121 5.2E-21 T 06-07-2017 IPR007263 Protein of unknown function DUF393 CAK77_RS22095 3c5155b47a48620cc4feae89c7b1027b 162 Pfam PF01613 Flavin reductase like domain 17 160 2.1E-28 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 CAK77_RS22095 3c5155b47a48620cc4feae89c7b1027b 162 SUPERFAMILY SSF50475 8 159 3.43E-39 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS22095 3c5155b47a48620cc4feae89c7b1027b 162 SMART SM00903 16 159 2.2E-42 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 CAK77_RS22095 3c5155b47a48620cc4feae89c7b1027b 162 Gene3D G3DSA:2.30.110.10 4 158 3.0E-46 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS11350 c65bfd3ef18790587ddc2f87081afec2 167 SUPERFAMILY SSF46767 84 163 1.57E-20 T 06-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CAK77_RS11350 c65bfd3ef18790587ddc2f87081afec2 167 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 85 163 3.7E-20 T 06-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CAK77_RS11350 c65bfd3ef18790587ddc2f87081afec2 167 Gene3D G3DSA:1.10.10.10 84 165 2.1E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS11350 c65bfd3ef18790587ddc2f87081afec2 167 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 85 162 1.1E-22 T 06-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CAK77_RS11350 c65bfd3ef18790587ddc2f87081afec2 167 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 133 139 - T 06-07-2017 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CAK77_RS16375 b3681be2289ebe141c0065a965e1e363 204 SUPERFAMILY SSF53448 11 199 1.55E-28 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK77_RS16375 b3681be2289ebe141c0065a965e1e363 204 Pfam PF01983 Guanylyl transferase CofC like 11 167 1.5E-8 T 06-07-2017 IPR002835 2-phospho-L-lactate guanylyltransferase, CofC GO:0016779 KEGG: 00680+2.7.7.68|MetaCyc: PWY-5198 CAK77_RS16375 b3681be2289ebe141c0065a965e1e363 204 Gene3D G3DSA:3.90.550.10 11 186 1.8E-29 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK77_RS16375 b3681be2289ebe141c0065a965e1e363 204 Hamap MF_02114 2-phospho-L-lactate guanylyltransferase [cofC]. 9 201 20.684 T 06-07-2017 IPR002835 2-phospho-L-lactate guanylyltransferase, CofC GO:0016779 KEGG: 00680+2.7.7.68|MetaCyc: PWY-5198 CAK77_RS16375 b3681be2289ebe141c0065a965e1e363 204 TIGRFAM TIGR03552 F420_cofC: 2-phospho-L-lactate guanylyltransferase 11 200 3.4E-52 T 06-07-2017 IPR002835 2-phospho-L-lactate guanylyltransferase, CofC GO:0016779 KEGG: 00680+2.7.7.68|MetaCyc: PWY-5198 CAK77_RS17105 8e052f4dd6b6baa374271227be43a53d 441 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 30 389 8.7E-13 T 06-07-2017 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 CAK77_RS23680 ae5ae5d336040d877a8c0ebbe850669d 211 Pfam PF01966 HD domain 31 118 3.0E-7 T 06-07-2017 IPR006674 HD domain CAK77_RS23680 ae5ae5d336040d877a8c0ebbe850669d 211 Gene3D G3DSA:1.10.3210.10 20 129 1.1E-7 T 06-07-2017 IPR006674 HD domain CAK77_RS23680 ae5ae5d336040d877a8c0ebbe850669d 211 SUPERFAMILY SSF109604 12 137 2.68E-16 T 06-07-2017 CAK77_RS10610 48821d0828bfcd348e8aa23106fd5c00 382 Gene3D G3DSA:3.40.710.10 3 379 1.1E-81 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK77_RS10610 48821d0828bfcd348e8aa23106fd5c00 382 SUPERFAMILY SSF56601 6 379 1.93E-87 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAK77_RS10610 48821d0828bfcd348e8aa23106fd5c00 382 ProSitePatterns PS00146 Beta-lactamase class-A active site. 60 75 - T 06-07-2017 IPR023650 Beta-lactamase, class-A active site KEGG: 00311+3.5.2.6 CAK77_RS10610 48821d0828bfcd348e8aa23106fd5c00 382 Pfam PF00144 Beta-lactamase 12 366 2.7E-66 T 06-07-2017 IPR001466 Beta-lactamase-related CAK77_RS14440 da1332b4588083efeaf6d794fbc46620 234 Pfam PF01988 VIT family 19 226 5.9E-57 T 06-07-2017 IPR008217 Ccc1 family CAK77_RS04445 b5cde26f5dd5d9343d6e83f7b4ff5430 245 Pfam PF11228 Protein of unknown function (DUF3027) 31 222 1.4E-78 T 06-07-2017 IPR021391 Protein of unknown function DUF3027 CAK77_RS18560 35085000544192b64311aa5cfe89a7f0 130 SUPERFAMILY SSF53041 37 129 8.24E-12 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CAK77_RS18560 35085000544192b64311aa5cfe89a7f0 130 Pfam PF00239 Resolvase, N terminal domain 42 129 7.2E-12 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CAK77_RS18560 35085000544192b64311aa5cfe89a7f0 130 Gene3D G3DSA:3.40.50.1390 37 130 7.5E-12 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CAK77_RS04215 8a3245b6fae7c54709dd2ee59a7bbc02 145 Gene3D G3DSA:3.30.530.20 7 144 4.7E-15 T 06-07-2017 IPR023393 START-like domain CAK77_RS04215 8a3245b6fae7c54709dd2ee59a7bbc02 145 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 6 140 7.6E-18 T 06-07-2017 IPR019587 Polyketide cyclase/dehydrase CAK77_RS04215 8a3245b6fae7c54709dd2ee59a7bbc02 145 SUPERFAMILY SSF55961 1 142 7.41E-30 T 06-07-2017 CAK77_RS07710 87eb42340037552c6b40c249d1c3346c 406 Pfam PF03734 L,D-transpeptidase catalytic domain 254 374 4.6E-17 T 06-07-2017 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 CAK77_RS07710 87eb42340037552c6b40c249d1c3346c 406 Gene3D G3DSA:2.40.440.10 254 375 1.6E-18 T 06-07-2017 CAK77_RS07710 87eb42340037552c6b40c249d1c3346c 406 SUPERFAMILY SSF141523 253 374 1.96E-28 T 06-07-2017 CAK77_RS04565 8fa6bb869593d28d2ddf4a60495020d8 351 Pfam PF11583 P-aminobenzoate N-oxygenase AurF 17 301 2.5E-110 T 06-07-2017 IPR025859 P-aminobenzoate N-oxygenase AurF CAK77_RS04565 8fa6bb869593d28d2ddf4a60495020d8 351 SUPERFAMILY SSF47240 67 233 2.26E-7 T 06-07-2017 IPR009078 Ferritin-like superfamily CAK77_RS09835 0c9e5b46ba313d88a0ed41fa319ed826 211 Pfam PF16859 Bacterial transcriptional repressor C-terminal 92 196 1.7E-11 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS09835 0c9e5b46ba313d88a0ed41fa319ed826 211 Gene3D G3DSA:1.10.357.10 70 200 1.8E-12 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS09835 0c9e5b46ba313d88a0ed41fa319ed826 211 Gene3D G3DSA:1.10.10.60 20 68 5.9E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS09835 0c9e5b46ba313d88a0ed41fa319ed826 211 Pfam PF00440 Bacterial regulatory proteins, tetR family 30 74 7.1E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS09835 0c9e5b46ba313d88a0ed41fa319ed826 211 SUPERFAMILY SSF46689 19 77 1.59E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS09835 0c9e5b46ba313d88a0ed41fa319ed826 211 SUPERFAMILY SSF48498 92 200 1.59E-9 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS09500 382c46bcac7e22d85687bc2bc4d4b37e 348 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 150 343 9.1E-51 T 06-07-2017 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CAK77_RS09500 382c46bcac7e22d85687bc2bc4d4b37e 348 Gene3D G3DSA:3.90.1510.10 38 147 1.7E-33 T 06-07-2017 IPR018193 Glycerate kinase, flavodoxin-like domain GO:0008887|GO:0031388 CAK77_RS09500 382c46bcac7e22d85687bc2bc4d4b37e 348 Gene3D G3DSA:3.90.1510.10 149 247 5.0E-29 T 06-07-2017 IPR018193 Glycerate kinase, flavodoxin-like domain GO:0008887|GO:0031388 CAK77_RS09500 382c46bcac7e22d85687bc2bc4d4b37e 348 Pfam PF02595 Glycerate kinase family 150 345 3.9E-56 T 06-07-2017 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CAK77_RS09500 382c46bcac7e22d85687bc2bc4d4b37e 348 Pfam PF02595 Glycerate kinase family 1 147 2.1E-41 T 06-07-2017 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CAK77_RS09500 382c46bcac7e22d85687bc2bc4d4b37e 348 SUPERFAMILY SSF110738 1 344 1.83E-88 T 06-07-2017 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CAK77_RS08925 8ac80e238079ebf6efb1ceaf4847066a 170 SUPERFAMILY SSF46785 41 157 2.16E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS08925 8ac80e238079ebf6efb1ceaf4847066a 170 ProSitePatterns PS01117 MarR-type HTH domain signature. 81 115 - T 06-07-2017 IPR023187 Transcriptional regulator MarR-type, conserved site CAK77_RS08925 8ac80e238079ebf6efb1ceaf4847066a 170 Pfam PF01047 MarR family 63 107 3.7E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK77_RS08925 8ac80e238079ebf6efb1ceaf4847066a 170 SMART SM00347 45 145 8.6E-4 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK77_RS08925 8ac80e238079ebf6efb1ceaf4847066a 170 Gene3D G3DSA:1.10.10.10 49 157 6.2E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS22470 2abbfba0b391cb264165ca7433fe0ab4 348 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 26 291 6.0E-47 T 06-07-2017 IPR005693 Virulence factor Mce protein CAK77_RS22470 2abbfba0b391cb264165ca7433fe0ab4 348 Pfam PF02470 MlaD protein 49 122 3.8E-15 T 06-07-2017 IPR003399 Mce/MlaD CAK77_RS23410 831c6624e2e9b5df6b8688f988744980 471 SUPERFAMILY SSF52777 40 166 1.06E-5 T 06-07-2017 CAK77_RS15195 d159e58899aa38bee4b997d92592ba00 227 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 31 223 2.7E-15 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS15195 d159e58899aa38bee4b997d92592ba00 227 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 10 117 1.8E-14 T 06-07-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CAK77_RS15195 d159e58899aa38bee4b997d92592ba00 227 SUPERFAMILY SSF161098 10 210 4.58E-36 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS15195 d159e58899aa38bee4b997d92592ba00 227 Gene3D G3DSA:1.10.3720.10 10 223 1.0E-37 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS11505 c33c420e9ce4b909d663c5bb9a01d1ea 310 Pfam PF11382 Copper transport outer membrane protein, MctB 2 308 6.3E-101 T 06-07-2017 IPR021522 Copper transporter MctB GO:0006810 CAK77_RS13130 a987267b0d235f2aad9de7c658737991 406 Pfam PF01494 FAD binding domain 2 319 2.1E-16 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 CAK77_RS13130 a987267b0d235f2aad9de7c658737991 406 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 5.6E-12 T 06-07-2017 CAK77_RS13130 a987267b0d235f2aad9de7c658737991 406 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 295 311 5.6E-12 T 06-07-2017 CAK77_RS13130 a987267b0d235f2aad9de7c658737991 406 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 146 161 5.6E-12 T 06-07-2017 CAK77_RS13130 a987267b0d235f2aad9de7c658737991 406 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 280 295 5.6E-12 T 06-07-2017 CAK77_RS13130 a987267b0d235f2aad9de7c658737991 406 SUPERFAMILY SSF51905 1 167 4.53E-43 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS13130 a987267b0d235f2aad9de7c658737991 406 SUPERFAMILY SSF51905 267 353 4.53E-43 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS13130 a987267b0d235f2aad9de7c658737991 406 Gene3D G3DSA:3.50.50.60 1 172 3.4E-26 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS13130 a987267b0d235f2aad9de7c658737991 406 Gene3D G3DSA:3.50.50.60 268 337 3.4E-26 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS15505 6b3f6c6a97d130183e20115a71ddeea1 158 Pfam PF02627 Carboxymuconolactone decarboxylase family 20 99 3.5E-5 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CAK77_RS15505 6b3f6c6a97d130183e20115a71ddeea1 158 Gene3D G3DSA:1.20.1290.10 14 151 3.2E-28 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAK77_RS15505 6b3f6c6a97d130183e20115a71ddeea1 158 SUPERFAMILY SSF69118 13 150 1.7E-25 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAK77_RS06295 1f6d10ed0c9b06f0baa53c3697285173 410 Pfam PF13742 OB-fold nucleic acid binding domain 13 106 2.1E-14 T 06-07-2017 IPR025824 OB-fold nucleic acid binding domain GO:0003676 CAK77_RS06295 1f6d10ed0c9b06f0baa53c3697285173 410 Pfam PF02601 Exonuclease VII, large subunit 330 403 1.3E-7 T 06-07-2017 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 CAK77_RS06295 1f6d10ed0c9b06f0baa53c3697285173 410 Pfam PF02601 Exonuclease VII, large subunit 130 349 1.8E-62 T 06-07-2017 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 CAK77_RS06295 1f6d10ed0c9b06f0baa53c3697285173 410 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 14 406 1.4E-113 T 06-07-2017 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 CAK77_RS06295 1f6d10ed0c9b06f0baa53c3697285173 410 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 6 406 24.977 T 06-07-2017 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 CAK77_RS11530 db8a26527de13a1ee85590ec16bbb2df 293 Pfam PF02616 Segregation and condensation protein ScpA 53 277 2.7E-65 T 06-07-2017 IPR003768 Segregation and condensation protein A CAK77_RS23165 ade448b70d303175b266dd54ce1008a9 165 Pfam PF13473 Cupredoxin-like domain 87 164 7.1E-11 T 06-07-2017 IPR028096 EfeO-type cupredoxin-like domain CAK77_RS23165 ade448b70d303175b266dd54ce1008a9 165 Gene3D G3DSA:2.60.40.420 76 164 1.6E-26 T 06-07-2017 IPR008972 Cupredoxin CAK77_RS23165 ade448b70d303175b266dd54ce1008a9 165 SUPERFAMILY SSF49503 74 164 8.03E-26 T 06-07-2017 IPR008972 Cupredoxin CAK77_RS08880 ef9a7c0973a6ef4f2ed14dcf2aa5d1af 344 SUPERFAMILY SSF55486 69 344 5.31E-67 T 06-07-2017 CAK77_RS08880 ef9a7c0973a6ef4f2ed14dcf2aa5d1af 344 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 95 179 9.0E-31 T 06-07-2017 IPR013856 Peptidase M4 domain GO:0004222 CAK77_RS08880 ef9a7c0973a6ef4f2ed14dcf2aa5d1af 344 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 191 202 2.2E-27 T 06-07-2017 IPR023612 Peptidase M4 GO:0004222|GO:0006508 CAK77_RS08880 ef9a7c0973a6ef4f2ed14dcf2aa5d1af 344 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 266 282 2.2E-27 T 06-07-2017 IPR023612 Peptidase M4 GO:0004222|GO:0006508 CAK77_RS08880 ef9a7c0973a6ef4f2ed14dcf2aa5d1af 344 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 134 154 2.2E-27 T 06-07-2017 IPR023612 Peptidase M4 GO:0004222|GO:0006508 CAK77_RS08880 ef9a7c0973a6ef4f2ed14dcf2aa5d1af 344 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 170 186 2.2E-27 T 06-07-2017 IPR023612 Peptidase M4 GO:0004222|GO:0006508 CAK77_RS08880 ef9a7c0973a6ef4f2ed14dcf2aa5d1af 344 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 182 343 7.5E-34 T 06-07-2017 IPR001570 Peptidase M4, C-terminal GO:0004222 CAK77_RS08880 ef9a7c0973a6ef4f2ed14dcf2aa5d1af 344 Gene3D G3DSA:3.10.170.10 69 183 3.2E-40 T 06-07-2017 IPR013856 Peptidase M4 domain GO:0004222 CAK77_RS08880 ef9a7c0973a6ef4f2ed14dcf2aa5d1af 344 Gene3D G3DSA:1.10.390.10 184 343 1.4E-36 T 06-07-2017 CAK77_RS23200 bdbfd1e30f25694aad3d92d5fe61f531 219 Pfam PF09335 SNARE associated Golgi protein 46 173 1.1E-21 T 06-07-2017 IPR032816 SNARE associated Golgi protein CAK77_RS16860 438bdffd736a1890cdfe2352509ca53f 346 Gene3D G3DSA:3.40.50.1980 188 338 2.7E-18 T 06-07-2017 CAK77_RS16860 438bdffd736a1890cdfe2352509ca53f 346 Gene3D G3DSA:3.40.50.1980 71 187 8.8E-27 T 06-07-2017 CAK77_RS16860 438bdffd736a1890cdfe2352509ca53f 346 SUPERFAMILY SSF53807 67 328 2.9E-50 T 06-07-2017 CAK77_RS16860 438bdffd736a1890cdfe2352509ca53f 346 Pfam PF01497 Periplasmic binding protein 90 319 2.1E-17 T 06-07-2017 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CAK77_RS06605 e1625415e17c6bc2cbba4125f8b09a83 253 SUPERFAMILY SSF53335 38 226 1.64E-35 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS06605 e1625415e17c6bc2cbba4125f8b09a83 253 Pfam PF01596 O-methyltransferase 71 211 5.7E-16 T 06-07-2017 IPR002935 O-methyltransferase, family 3 GO:0008171 CAK77_RS06605 e1625415e17c6bc2cbba4125f8b09a83 253 Gene3D G3DSA:3.40.50.150 36 221 4.8E-46 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS10050 e5385b57af0050d0a07dc47c7bc95fbf 210 Gene3D G3DSA:1.10.357.10 12 197 4.7E-23 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS10050 e5385b57af0050d0a07dc47c7bc95fbf 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 70 3.9E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS10050 e5385b57af0050d0a07dc47c7bc95fbf 210 SUPERFAMILY SSF46689 15 86 1.95E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS16685 b7c63bd58fab897fa338f837c2a44fe2 285 SUPERFAMILY SSF52266 35 277 7.0E-47 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAK77_RS16685 b7c63bd58fab897fa338f837c2a44fe2 285 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 38 267 6.1E-18 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAK77_RS16685 b7c63bd58fab897fa338f837c2a44fe2 285 Gene3D G3DSA:3.40.50.1110 30 278 2.5E-44 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAK77_RS11560 5ed645d7a8336d421d8aaca19f4b966a 454 Pfam PF02720 Domain of unknown function (DUF222) 39 363 1.3E-72 T 06-07-2017 IPR003870 Domain of unknown function DUF222 CAK77_RS11560 5ed645d7a8336d421d8aaca19f4b966a 454 ProDom PD008243 RV1792C/MT1741/MB1728C RV1945/MT1995 MB1980 MB0098C RV3466/MT3572 VERY RV1128C/MT1160 RV1148C/MT1183 MB1159C RV0095C 1 72 0.001 T 06-07-2017 CAK77_RS14625 c77bae026ee7e45af09df98acc10c871 664 Gene3D G3DSA:1.10.3330.10 491 645 1.5E-33 T 06-07-2017 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394 CAK77_RS14625 c77bae026ee7e45af09df98acc10c871 664 Pfam PF09349 OHCU decarboxylase 489 639 1.2E-25 T 06-07-2017 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394 CAK77_RS14625 c77bae026ee7e45af09df98acc10c871 664 SUPERFAMILY SSF158694 485 643 6.28E-35 T 06-07-2017 CAK77_RS14625 c77bae026ee7e45af09df98acc10c871 664 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 363 383 - T 06-07-2017 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 CAK77_RS14625 c77bae026ee7e45af09df98acc10c871 664 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 29 466 3.9E-105 T 06-07-2017 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 CAK77_RS14625 c77bae026ee7e45af09df98acc10c871 664 TIGRFAM TIGR03173 pbuX: xanthine permease 33 414 2.3E-137 T 06-07-2017 IPR017588 Uric acid permease UacT-like GO:0006810|GO:0016021 CAK77_RS14625 c77bae026ee7e45af09df98acc10c871 664 Pfam PF00860 Permease family 30 413 9.6E-95 T 06-07-2017 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CAK77_RS20810 e434050b7beaf7891f6953c93280d556 344 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 9 290 1.6E-75 T 06-07-2017 IPR005693 Virulence factor Mce protein CAK77_RS20810 e434050b7beaf7891f6953c93280d556 344 Pfam PF02470 MlaD protein 35 111 2.7E-17 T 06-07-2017 IPR003399 Mce/MlaD CAK77_RS08775 af038dd37adc59f3f3331d6b2f0ad35e 458 SUPERFAMILY SSF111283 5 451 3.4E-65 T 06-07-2017 CAK77_RS08775 af038dd37adc59f3f3331d6b2f0ad35e 458 Pfam PF01523 Putative modulator of DNA gyrase 26 320 5.5E-30 T 06-07-2017 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 CAK77_RS22720 925f83675b84be157d4868a4e0de3519 377 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 18 304 3.4E-48 T 06-07-2017 IPR005693 Virulence factor Mce protein CAK77_RS22720 925f83675b84be157d4868a4e0de3519 377 Pfam PF02470 MlaD protein 43 115 1.7E-14 T 06-07-2017 IPR003399 Mce/MlaD CAK77_RS23475 566b92f110a6eac91c1ae12898361d28 86 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 80 17.258 T 06-07-2017 IPR003482 Transcription factor WhiB CAK77_RS23475 566b92f110a6eac91c1ae12898361d28 86 Pfam PF02467 Transcription factor WhiB 3 71 1.4E-19 T 06-07-2017 IPR003482 Transcription factor WhiB CAK77_RS03915 9efb1ace82fc0727335a61a1d4c4f376 59 Pfam PF11273 Protein of unknown function (DUF3073) 2 57 3.3E-22 T 06-07-2017 IPR021426 Protein of unknown function DUF3073 CAK77_RS00860 048dc6f21f5d242b7b66dc8384f3c4f5 273 ProSitePatterns PS01174 Lipolytic enzymes "G-D-X-G" family, putative serine active site. 106 118 - T 06-07-2017 IPR033140 Lipase, GDXG, putative serine active site CAK77_RS00860 048dc6f21f5d242b7b66dc8384f3c4f5 273 Gene3D G3DSA:3.40.50.1820 26 259 6.5E-53 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS00860 048dc6f21f5d242b7b66dc8384f3c4f5 273 Pfam PF07859 alpha/beta hydrolase fold 38 239 8.4E-41 T 06-07-2017 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CAK77_RS00860 048dc6f21f5d242b7b66dc8384f3c4f5 273 SUPERFAMILY SSF53474 29 261 3.95E-41 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS10835 5c46089c3f6e5e1cda29ed9837550b65 166 Pfam PF03073 TspO/MBR family 20 159 2.4E-42 T 06-07-2017 IPR004307 TspO/MBR-related protein GO:0016021 CAK77_RS10835 5c46089c3f6e5e1cda29ed9837550b65 166 PIRSF PIRSF005859 10 163 5.7E-45 T 06-07-2017 IPR004307 TspO/MBR-related protein GO:0016021 CAK77_RS11470 06084fad7030648f9ec4d049cfae748b 297 Pfam PF12688 Tetratrico peptide repeat 189 279 8.9E-5 T 06-07-2017 CAK77_RS11470 06084fad7030648f9ec4d049cfae748b 297 Gene3D G3DSA:1.25.40.10 252 279 9.6E-5 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK77_RS11470 06084fad7030648f9ec4d049cfae748b 297 Gene3D G3DSA:1.25.40.10 125 212 9.6E-5 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK77_RS06150 b68f1bd8bfd69f403c370a81f9d7f074 215 Gene3D G3DSA:1.10.3720.10 17 197 7.7E-20 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS06150 b68f1bd8bfd69f403c370a81f9d7f074 215 SUPERFAMILY SSF161098 17 200 3.53E-26 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS06150 b68f1bd8bfd69f403c370a81f9d7f074 215 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 36 205 3.5E-17 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS14025 ecdd1581b67e5b785f8c5609ddb7494e 295 SUPERFAMILY SSF55486 137 274 1.47E-5 T 06-07-2017 CAK77_RS14025 ecdd1581b67e5b785f8c5609ddb7494e 295 Pfam PF04228 Putative neutral zinc metallopeptidase 12 289 1.1E-74 T 06-07-2017 IPR007343 Uncharacterised protein family, zinc metallopeptidase putative CAK77_RS23560 eaa80f5fde1629e17fc192404a555a9d 120 Pfam PF13564 DoxX-like family 10 111 5.5E-19 T 06-07-2017 IPR032808 DoxX family CAK77_RS15815 501053981e4257e6d91863dfbcc155fe 217 Pfam PF13649 Methyltransferase domain 46 140 1.9E-16 T 06-07-2017 CAK77_RS15815 501053981e4257e6d91863dfbcc155fe 217 SUPERFAMILY SSF53335 5 191 2.89E-39 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS15815 501053981e4257e6d91863dfbcc155fe 217 Gene3D G3DSA:3.40.50.150 25 197 3.8E-40 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS16340 f327ae0a1799954d26610c77dab8582a 416 SUPERFAMILY SSF53474 111 415 7.02E-17 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS16340 f327ae0a1799954d26610c77dab8582a 416 Pfam PF03583 Secretory lipase 169 414 7.3E-37 T 06-07-2017 IPR005152 Lipase, secreted GO:0004806|GO:0016042 KEGG: 00561+3.1.1.3|MetaCyc: PWY-6857 CAK77_RS16340 f327ae0a1799954d26610c77dab8582a 416 PIRSF PIRSF029171 53 416 1.9E-23 T 06-07-2017 IPR005152 Lipase, secreted GO:0004806|GO:0016042 KEGG: 00561+3.1.1.3|MetaCyc: PWY-6857 CAK77_RS16340 f327ae0a1799954d26610c77dab8582a 416 Gene3D G3DSA:3.40.50.1820 111 259 1.5E-14 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS16340 f327ae0a1799954d26610c77dab8582a 416 Gene3D G3DSA:3.40.50.1820 294 414 1.5E-14 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS15755 7863716f74cd02e17d221b01097d32a3 124 SUPERFAMILY SSF54593 9 118 8.01E-14 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK77_RS15755 7863716f74cd02e17d221b01097d32a3 124 Gene3D G3DSA:3.10.180.10 9 117 4.6E-9 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK77_RS00380 ba49590adff3b3026e2f42d0c83a29ae 388 SUPERFAMILY SSF56059 1 167 1.91E-70 T 06-07-2017 CAK77_RS00380 ba49590adff3b3026e2f42d0c83a29ae 388 SUPERFAMILY SSF56059 270 384 1.91E-70 T 06-07-2017 CAK77_RS00380 ba49590adff3b3026e2f42d0c83a29ae 388 SUPERFAMILY SSF52440 174 283 1.9E-36 T 06-07-2017 IPR016185 Pre-ATP-grasp domain CAK77_RS00380 ba49590adff3b3026e2f42d0c83a29ae 388 Pfam PF03738 Glutathionylspermidine synthase preATP-grasp 12 385 1.7E-144 T 06-07-2017 IPR005494 Glutathionylspermidine synthase, pre-ATP-grasp-like domain CAK77_RS15775 10c6d7de45b7c67f54df71c97a34fcd8 411 Pfam PF02163 Peptidase family M50 11 381 3.0E-49 T 06-07-2017 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033 CAK77_RS15775 10c6d7de45b7c67f54df71c97a34fcd8 411 Gene3D G3DSA:2.30.42.10 102 222 4.9E-17 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAK77_RS15775 10c6d7de45b7c67f54df71c97a34fcd8 411 SUPERFAMILY SSF50156 149 220 8.81E-12 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAK77_RS15775 10c6d7de45b7c67f54df71c97a34fcd8 411 SUPERFAMILY SSF50156 96 120 8.81E-12 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAK77_RS03125 6c8cd30f00a24c72b9d0910d6047706c 357 Pfam PF03060 Nitronate monooxygenase 82 343 1.2E-73 T 06-07-2017 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 CAK77_RS03125 6c8cd30f00a24c72b9d0910d6047706c 357 Gene3D G3DSA:3.20.20.70 5 338 8.2E-69 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK77_RS03125 6c8cd30f00a24c72b9d0910d6047706c 357 SUPERFAMILY SSF51412 5 251 5.95E-58 T 06-07-2017 CAK77_RS03125 6c8cd30f00a24c72b9d0910d6047706c 357 SUPERFAMILY SSF51412 311 346 5.95E-58 T 06-07-2017 CAK77_RS17650 4406f67fb4e6b64e9bfeba3a43bfc132 284 TIGRFAM TIGR02569 TIGR02569_actnb: TIGR02569 family protein 5 280 6.2E-124 T 06-07-2017 IPR013402 Conserved hypothetical protein CHP02569 CAK77_RS13255 105d70ea3df3392d60cc2b200b00d266 419 SUPERFAMILY SSF103473 20 411 2.62E-59 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK77_RS13255 105d70ea3df3392d60cc2b200b00d266 419 Gene3D G3DSA:1.20.1250.20 231 407 1.4E-18 T 06-07-2017 CAK77_RS13255 105d70ea3df3392d60cc2b200b00d266 419 Gene3D G3DSA:1.20.1250.20 33 210 1.2E-24 T 06-07-2017 CAK77_RS13255 105d70ea3df3392d60cc2b200b00d266 419 Pfam PF07690 Major Facilitator Superfamily 37 255 5.0E-24 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK77_RS13255 105d70ea3df3392d60cc2b200b00d266 419 Pfam PF07690 Major Facilitator Superfamily 268 416 2.9E-12 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK77_RS02285 613de028a16284575680805fcc4dccc5 53 Pfam PF13783 Domain of unknown function (DUF4177) 7 45 2.2E-6 T 06-07-2017 IPR025234 Protein of unknown function DUF4177 CAK77_RS18460 3be5f2df942431156c5516f2e43dddfe 168 Pfam PF03703 Bacterial PH domain 91 159 9.7E-5 T 06-07-2017 IPR005182 Domain of unknown function DUF304 CAK77_RS07410 9aa9826cb695d3daf6abcc499bb24fe5 197 Gene3D G3DSA:1.10.357.10 11 188 6.2E-18 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS07410 9aa9826cb695d3daf6abcc499bb24fe5 197 SUPERFAMILY SSF46689 11 92 5.64E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS11310 4133c6b4227c00fa8bbee9f318e43a14 250 Gene3D G3DSA:3.40.1280.10 94 247 6.2E-44 T 06-07-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CAK77_RS11310 4133c6b4227c00fa8bbee9f318e43a14 250 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 20 83 3.7E-8 T 06-07-2017 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 CAK77_RS11310 4133c6b4227c00fa8bbee9f318e43a14 250 SUPERFAMILY SSF75217 86 247 5.36E-37 T 06-07-2017 IPR029028 Alpha/beta knot methyltransferases CAK77_RS11310 4133c6b4227c00fa8bbee9f318e43a14 250 Pfam PF00588 SpoU rRNA Methylase family 99 241 4.4E-32 T 06-07-2017 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CAK77_RS11310 4133c6b4227c00fa8bbee9f318e43a14 250 SUPERFAMILY SSF55315 3 84 1.46E-15 T 06-07-2017 IPR029064 50S ribosomal protein L30e-like CAK77_RS11310 4133c6b4227c00fa8bbee9f318e43a14 250 SMART SM00967 20 88 1.3E-12 T 06-07-2017 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 CAK77_RS11310 4133c6b4227c00fa8bbee9f318e43a14 250 Gene3D G3DSA:3.30.1330.30 3 84 1.4E-19 T 06-07-2017 IPR029064 50S ribosomal protein L30e-like CAK77_RS09180 3fa4b6cefe64253ccd40be7b511a9209 336 TIGRFAM TIGR00802 nico: transition metal uptake transporter, Ni2+-Co2+ transporter (NiCoT) family 37 318 4.5E-108 T 06-07-2017 IPR004688 Transition metal uptake transporter nickel/cobalt GO:0015099|GO:0016021|GO:0035444|GO:0046872 CAK77_RS09180 3fa4b6cefe64253ccd40be7b511a9209 336 Pfam PF03824 High-affinity nickel-transport protein 35 323 1.6E-76 T 06-07-2017 IPR011541 Nickel/cobalt transporter, high-affinity GO:0015099|GO:0016021|GO:0035444|GO:0046872 CAK77_RS21715 5423f8c7b67d1a92158e35082c52f532 589 Pfam PF14021 Protein of unknown function (DUF4237) 484 582 1.6E-21 T 06-07-2017 IPR025331 Protein of unknown function DUF4237 CAK77_RS20820 0a36114e75e108b8c516ec089eb275f2 286 Pfam PF02405 Permease MlaE 70 273 7.4E-52 T 06-07-2017 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 CAK77_RS07580 3297c641a3cbcc4a95dd635599fb48d3 227 Pfam PF14032 PknH-like extracellular domain 38 217 1.3E-21 T 06-07-2017 IPR026954 PknH-like extracellular domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 CAK77_RS07245 f43a6942ea18161f88aac3ed33459c66 226 Pfam PF01300 Telomere recombination 23 197 8.5E-48 T 06-07-2017 IPR006070 YrdC-like domain GO:0003725 CAK77_RS07245 f43a6942ea18161f88aac3ed33459c66 226 Gene3D G3DSA:3.90.870.10 4 209 1.8E-67 T 06-07-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain CAK77_RS07245 f43a6942ea18161f88aac3ed33459c66 226 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 11 208 7.5E-65 T 06-07-2017 IPR006070 YrdC-like domain GO:0003725 CAK77_RS07245 f43a6942ea18161f88aac3ed33459c66 226 SUPERFAMILY SSF55821 5 210 9.16E-59 T 06-07-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain CAK77_RS22455 092e46599c7ab436da54b706390a393a 416 Pfam PF02470 MlaD protein 52 125 6.6E-12 T 06-07-2017 IPR003399 Mce/MlaD CAK77_RS20180 9f7addf05d5c088d324f3a36968f3c32 320 Pfam PF02405 Permease MlaE 100 310 3.4E-60 T 06-07-2017 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 CAK77_RS01615 0be15822edf25e86648c3d41b5c144f4 146 PIRSF PIRSF017371 1 145 2.6E-74 T 06-07-2017 IPR014488 Uncharacterised conserved protein UCP017371 CAK77_RS01615 0be15822edf25e86648c3d41b5c144f4 146 Gene3D G3DSA:3.30.530.20 1 105 3.6E-6 T 06-07-2017 IPR023393 START-like domain CAK77_RS01615 0be15822edf25e86648c3d41b5c144f4 146 SUPERFAMILY SSF55961 3 132 2.75E-14 T 06-07-2017 CAK77_RS01615 0be15822edf25e86648c3d41b5c144f4 146 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 4 144 1.5E-22 T 06-07-2017 IPR019587 Polyketide cyclase/dehydrase CAK77_RS05455 aec7aced011ca5626ef7bd2c1f74b988 192 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 1 178 2.2E-36 T 06-07-2017 IPR002698 5-formyltetrahydrofolate cyclo-ligase CAK77_RS05455 aec7aced011ca5626ef7bd2c1f74b988 192 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 1 178 7.8E-34 T 06-07-2017 IPR002698 5-formyltetrahydrofolate cyclo-ligase CAK77_RS05455 aec7aced011ca5626ef7bd2c1f74b988 192 PIRSF PIRSF006806 1 182 2.6E-37 T 06-07-2017 IPR002698 5-formyltetrahydrofolate cyclo-ligase CAK77_RS05455 aec7aced011ca5626ef7bd2c1f74b988 192 SUPERFAMILY SSF100950 1 185 2.79E-35 T 06-07-2017 CAK77_RS05455 aec7aced011ca5626ef7bd2c1f74b988 192 Gene3D G3DSA:3.40.50.10420 1 184 3.8E-39 T 06-07-2017 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain CAK77_RS02075 71e532d4b5a2cd479bb92afcb61884f6 333 SUPERFAMILY SSF116734 160 292 2.94E-10 T 06-07-2017 CAK77_RS02075 71e532d4b5a2cd479bb92afcb61884f6 333 Pfam PF01420 Type I restriction modification DNA specificity domain 160 306 2.7E-11 T 06-07-2017 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 CAK77_RS02075 71e532d4b5a2cd479bb92afcb61884f6 333 SUPERFAMILY SSF116734 3 116 1.42E-5 T 06-07-2017 CAK77_RS09045 4358a181011b20b66c97beb7998440f8 426 Pfam PF13556 PucR C-terminal helix-turn-helix domain 341 397 4.0E-21 T 06-07-2017 IPR025736 PucR C-terminal helix-turn-helix domain CAK77_RS11855 0f83d9080f62d6a748f7b086d4c54c3a 147 SUPERFAMILY SSF52402 8 145 4.1E-18 T 06-07-2017 CAK77_RS11855 0f83d9080f62d6a748f7b086d4c54c3a 147 Pfam PF00582 Universal stress protein family 9 145 1.6E-16 T 06-07-2017 IPR006016 UspA GO:0006950 CAK77_RS11855 0f83d9080f62d6a748f7b086d4c54c3a 147 Gene3D G3DSA:3.40.50.620 8 145 2.5E-19 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAK77_RS01100 cdd6f28206c9b44a96868ce76337a1f0 388 Pfam PF13191 AAA ATPase domain 15 188 6.1E-15 T 06-07-2017 CAK77_RS01100 cdd6f28206c9b44a96868ce76337a1f0 388 SUPERFAMILY SSF52540 163 279 6.09E-15 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS01100 cdd6f28206c9b44a96868ce76337a1f0 388 SUPERFAMILY SSF52540 6 120 6.09E-15 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS01100 cdd6f28206c9b44a96868ce76337a1f0 388 Gene3D G3DSA:3.40.50.300 16 101 1.5E-8 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS01100 cdd6f28206c9b44a96868ce76337a1f0 388 Gene3D G3DSA:3.40.50.300 147 190 1.5E-8 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS15510 a55491cec1fc719b4b8cce6371d8ee7c 206 Pfam PF12079 Protein of unknown function (DUF3558) 49 189 1.3E-9 T 06-07-2017 IPR024520 Protein of unknown function DUF3558 CAK77_RS09075 cb52040d8ea62b3c588533a1b1b77b1d 141 Pfam PF11253 Protein of unknown function (DUF3052) 11 134 3.4E-57 T 06-07-2017 IPR021412 Protein of unknown function DUF3052 CAK77_RS04745 a55dc63abdcf851fbacfb2619d978b80 378 SUPERFAMILY SSF53474 62 234 1.14E-20 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS04745 a55dc63abdcf851fbacfb2619d978b80 378 SUPERFAMILY SSF53474 301 355 1.14E-20 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS04745 a55dc63abdcf851fbacfb2619d978b80 378 PIRSF PIRSF029171 6 378 6.4E-82 T 06-07-2017 IPR005152 Lipase, secreted GO:0004806|GO:0016042 KEGG: 00561+3.1.1.3|MetaCyc: PWY-6857 CAK77_RS04745 a55dc63abdcf851fbacfb2619d978b80 378 Gene3D G3DSA:3.40.50.1820 63 222 1.5E-17 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS04745 a55dc63abdcf851fbacfb2619d978b80 378 Gene3D G3DSA:3.40.50.1820 267 355 1.5E-17 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS04745 a55dc63abdcf851fbacfb2619d978b80 378 Pfam PF03583 Secretory lipase 111 242 6.8E-16 T 06-07-2017 IPR005152 Lipase, secreted GO:0004806|GO:0016042 KEGG: 00561+3.1.1.3|MetaCyc: PWY-6857 CAK77_RS02630 1c3bcc99411ccfed958a419a34e10d49 310 SUPERFAMILY SSF51735 2 309 9.57E-89 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS02630 1c3bcc99411ccfed958a419a34e10d49 310 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 304 3.0E-58 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS02630 1c3bcc99411ccfed958a419a34e10d49 310 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 133 161 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK77_RS02630 1c3bcc99411ccfed958a419a34e10d49 310 Gene3D G3DSA:3.40.50.720 2 178 1.3E-53 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS02630 1c3bcc99411ccfed958a419a34e10d49 310 Gene3D G3DSA:3.90.25.10 179 297 1.9E-31 T 06-07-2017 CAK77_RS19245 07f3e1eec5bbdf02f6fe0ef192560752 184 ProDom PD103646 LIPOPROTEIN LPRB MEMBRANE PRECURSOR PALMITATE SIGNAL 56 181 8.0E-8 T 06-07-2017 CAK77_RS19245 07f3e1eec5bbdf02f6fe0ef192560752 184 Pfam PF12079 Protein of unknown function (DUF3558) 16 178 6.9E-26 T 06-07-2017 IPR024520 Protein of unknown function DUF3558 CAK77_RS05360 c0e6e68c3d9f24d5efbdaca489564c3c 416 Gene3D G3DSA:2.60.120.10 197 242 6.3E-6 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK77_RS05360 c0e6e68c3d9f24d5efbdaca489564c3c 416 SUPERFAMILY SSF51197 93 238 2.75E-9 T 06-07-2017 CAK77_RS19195 79e1b0cd4eb9bac295e0a8545f352e46 460 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 151 383 6.1E-22 T 06-07-2017 IPR018713 Domain of unknown function DUF2236 CAK77_RS13995 e66ad30245a9fa82108b0aca727cfeb8 329 Pfam PF03773 Predicted permease 43 318 4.8E-43 T 06-07-2017 IPR005524 Predicted permease DUF318 CAK77_RS17955 7c7f58c329958820082eae7d6e50c097 192 SUPERFAMILY SSF55811 60 175 4.33E-21 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAK77_RS17955 7c7f58c329958820082eae7d6e50c097 192 Pfam PF00293 NUDIX domain 60 175 6.7E-10 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 CAK77_RS17955 7c7f58c329958820082eae7d6e50c097 192 Gene3D G3DSA:3.90.79.10 60 180 1.3E-19 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAK77_RS04105 5ac5a84dd05b91cc1f36c14f41cc305d 300 SUPERFAMILY SSF103481 202 299 3.14E-12 T 06-07-2017 CAK77_RS04105 5ac5a84dd05b91cc1f36c14f41cc305d 300 Pfam PF00892 EamA-like transporter family 19 147 2.0E-15 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAK77_RS04105 5ac5a84dd05b91cc1f36c14f41cc305d 300 Pfam PF00892 EamA-like transporter family 163 295 7.1E-19 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAK77_RS04105 5ac5a84dd05b91cc1f36c14f41cc305d 300 SUPERFAMILY SSF103481 49 150 2.62E-12 T 06-07-2017 CAK77_RS09560 d1f28f14a7067e8f0ad1dd1443a54ec7 391 Gene3D G3DSA:2.102.10.10 170 197 1.9E-41 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK77_RS09560 d1f28f14a7067e8f0ad1dd1443a54ec7 391 Gene3D G3DSA:2.102.10.10 233 389 1.9E-41 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK77_RS09560 d1f28f14a7067e8f0ad1dd1443a54ec7 391 Pfam PF00355 Rieske [2Fe-2S] domain 300 363 3.7E-9 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK77_RS09560 d1f28f14a7067e8f0ad1dd1443a54ec7 391 SUPERFAMILY SSF50022 301 389 6.42E-24 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK77_RS11240 fd50b34de8fdeeea738a9a18055c98fc 478 SUPERFAMILY SSF103473 254 459 5.23E-28 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK77_RS11240 fd50b34de8fdeeea738a9a18055c98fc 478 SUPERFAMILY SSF103473 22 205 5.23E-28 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK77_RS11240 fd50b34de8fdeeea738a9a18055c98fc 478 Gene3D G3DSA:1.20.1250.20 281 463 5.3E-6 T 06-07-2017 CAK77_RS11240 fd50b34de8fdeeea738a9a18055c98fc 478 Gene3D G3DSA:1.20.1250.20 23 193 1.6E-14 T 06-07-2017 CAK77_RS11240 fd50b34de8fdeeea738a9a18055c98fc 478 Pfam PF07690 Major Facilitator Superfamily 27 418 1.3E-25 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK77_RS08770 89933b81f7bea362acb7c06a5295898c 505 SUPERFAMILY SSF111283 15 494 6.41E-94 T 06-07-2017 CAK77_RS08770 89933b81f7bea362acb7c06a5295898c 505 Pfam PF01523 Putative modulator of DNA gyrase 32 343 1.5E-49 T 06-07-2017 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 CAK77_RS21360 cdada883934e7b620eca2e0e6fcd325b 223 SUPERFAMILY SSF111331 36 84 4.14E-5 T 06-07-2017 IPR016064 NAD kinase/diacylglycerol kinase-like domain CAK77_RS21360 cdada883934e7b620eca2e0e6fcd325b 223 Pfam PF00781 Diacylglycerol kinase catalytic domain 33 84 3.5E-5 T 06-07-2017 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CAK77_RS04330 8ca09d0bd18e373c02947dc5d3f8dacb 454 SUPERFAMILY SSF52777 41 154 1.45E-9 T 06-07-2017 CAK77_RS04330 8ca09d0bd18e373c02947dc5d3f8dacb 454 Gene3D G3DSA:3.30.559.10 119 155 4.5E-4 T 06-07-2017 IPR023213 Chloramphenicol acetyltransferase-like domain Reactome: R-HSA-389661 CAK77_RS01780 87821a3d97554bee94664cd374c62a4a 216 Gene3D G3DSA:3.40.50.1480 89 148 2.1E-4 T 06-07-2017 CAK77_RS01780 87821a3d97554bee94664cd374c62a4a 216 Pfam PF14032 PknH-like extracellular domain 31 211 2.5E-38 T 06-07-2017 IPR026954 PknH-like extracellular domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 CAK77_RS09545 690beb006b937de153d1f5e829cb9c9d 236 Pfam PF10812 Protein of unknown function (DUF2561) 20 229 3.2E-47 T 06-07-2017 IPR024381 Protein of unknown function DUF2561 CAK77_RS09545 690beb006b937de153d1f5e829cb9c9d 236 ProDom PD111926 TRANSMEMBRANE MEMBRANE RV2197C/MT2253 PROBABLE ML0878 21 229 5.0E-6 T 06-07-2017 IPR024381 Protein of unknown function DUF2561 CAK77_RS04400 394515a6e20c60c7d3d0ea4a854268b9 262 Gene3D G3DSA:3.40.50.150 35 199 1.7E-33 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS04400 394515a6e20c60c7d3d0ea4a854268b9 262 Pfam PF13649 Methyltransferase domain 58 151 5.0E-21 T 06-07-2017 CAK77_RS04400 394515a6e20c60c7d3d0ea4a854268b9 262 SUPERFAMILY SSF53335 33 199 5.47E-36 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS18730 1bf6f26d37eb3796bf5cbbd3c6cc71d4 457 TIGRFAM TIGR03931 T7SS_Rv3446c: type VII secretion-associated protein, Rv3446c family 296 452 1.8E-36 T 06-07-2017 IPR023840 Type VII secretion system Rv3446c CAK77_RS23700 cefe042d14e6d413d7380b4d9715ac77 264 Gene3D G3DSA:1.10.10.60 5 42 6.2E-5 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS23700 cefe042d14e6d413d7380b4d9715ac77 264 Pfam PF00440 Bacterial regulatory proteins, tetR family 74 116 5.9E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS23700 cefe042d14e6d413d7380b4d9715ac77 264 SUPERFAMILY SSF46689 65 121 7.98E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS23700 cefe042d14e6d413d7380b4d9715ac77 264 SUPERFAMILY SSF48498 139 259 9.53E-6 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS23700 cefe042d14e6d413d7380b4d9715ac77 264 Gene3D G3DSA:1.10.357.10 55 257 3.9E-26 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS00670 6dfc7bbcfe9f79e9ca30907b4d22962a 198 Gene3D G3DSA:3.40.50.150 29 179 3.5E-23 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS00670 6dfc7bbcfe9f79e9ca30907b4d22962a 198 Pfam PF13649 Methyltransferase domain 41 132 9.8E-13 T 06-07-2017 CAK77_RS00670 6dfc7bbcfe9f79e9ca30907b4d22962a 198 SUPERFAMILY SSF53335 29 181 1.18E-24 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS13155 bced4de01c83141ffca01534a243deea 76 ProDom PD028237 MB1616 ML1221 CGL0073 RV1590/MT1625 11 74 1.0E-15 T 06-07-2017 CAK77_RS14900 8595f9e9ed754630e95a5e22953de82e 229 Pfam PF02254 TrkA-N domain 3 116 5.2E-23 T 06-07-2017 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 CAK77_RS14900 8595f9e9ed754630e95a5e22953de82e 229 SUPERFAMILY SSF51735 2 134 4.73E-24 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS14900 8595f9e9ed754630e95a5e22953de82e 229 SUPERFAMILY SSF116726 136 207 8.5E-5 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CAK77_RS14900 8595f9e9ed754630e95a5e22953de82e 229 Gene3D G3DSA:3.40.50.720 2 137 4.6E-28 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS08585 a72ee258dee20df91b7b0b415e05e5ea 440 Gene3D G3DSA:3.40.640.10 58 308 3.8E-58 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK77_RS08585 a72ee258dee20df91b7b0b415e05e5ea 440 Pfam PF00202 Aminotransferase class-III 21 433 1.4E-70 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAK77_RS08585 a72ee258dee20df91b7b0b415e05e5ea 440 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 244 281 - T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAK77_RS08585 a72ee258dee20df91b7b0b415e05e5ea 440 Gene3D G3DSA:3.90.1150.10 309 436 3.6E-42 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK77_RS08585 a72ee258dee20df91b7b0b415e05e5ea 440 SUPERFAMILY SSF53383 14 434 3.71E-98 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK77_RS13315 b52fd8c6e8f5cf078b6b7111a5df75c5 380 PRINTS PR00721 Stomatin signature 176 197 2.3E-32 T 06-07-2017 IPR001972 Stomatin family GO:0016020 CAK77_RS13315 b52fd8c6e8f5cf078b6b7111a5df75c5 380 PRINTS PR00721 Stomatin signature 133 156 2.3E-32 T 06-07-2017 IPR001972 Stomatin family GO:0016020 CAK77_RS13315 b52fd8c6e8f5cf078b6b7111a5df75c5 380 PRINTS PR00721 Stomatin signature 78 99 2.3E-32 T 06-07-2017 IPR001972 Stomatin family GO:0016020 CAK77_RS13315 b52fd8c6e8f5cf078b6b7111a5df75c5 380 PRINTS PR00721 Stomatin signature 30 52 2.3E-32 T 06-07-2017 IPR001972 Stomatin family GO:0016020 CAK77_RS13315 b52fd8c6e8f5cf078b6b7111a5df75c5 380 PRINTS PR00721 Stomatin signature 157 175 2.3E-32 T 06-07-2017 IPR001972 Stomatin family GO:0016020 CAK77_RS13315 b52fd8c6e8f5cf078b6b7111a5df75c5 380 PRINTS PR00721 Stomatin signature 113 130 2.3E-32 T 06-07-2017 IPR001972 Stomatin family GO:0016020 CAK77_RS13315 b52fd8c6e8f5cf078b6b7111a5df75c5 380 SUPERFAMILY SSF117892 54 188 1.44E-40 T 06-07-2017 IPR001107 Band 7 domain CAK77_RS13315 b52fd8c6e8f5cf078b6b7111a5df75c5 380 Pfam PF01145 SPFH domain / Band 7 family 28 196 4.7E-31 T 06-07-2017 IPR001107 Band 7 domain CAK77_RS13315 b52fd8c6e8f5cf078b6b7111a5df75c5 380 SMART SM00244 23 181 1.4E-56 T 06-07-2017 IPR001107 Band 7 domain CAK77_RS13315 b52fd8c6e8f5cf078b6b7111a5df75c5 380 ProSitePatterns PS01270 Band 7 protein family signature. 137 165 - T 06-07-2017 IPR018080 Band 7/stomatin-like, conserved site CAK77_RS11845 62ce029b03e569852a4580b3c1953fb9 156 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 25 145 17.715 T 06-07-2017 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CAK77_RS11845 62ce029b03e569852a4580b3c1953fb9 156 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 26 139 6.9E-22 T 06-07-2017 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CAK77_RS15335 154a063c566694e28720693caa82ea79 103 SUPERFAMILY SSF54909 1 93 5.01E-23 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAK77_RS15335 154a063c566694e28720693caa82ea79 103 Gene3D G3DSA:3.30.70.900 1 89 1.1E-22 T 06-07-2017 CAK77_RS15335 154a063c566694e28720693caa82ea79 103 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 71 1.1E-13 T 06-07-2017 IPR007138 Antibiotic biosynthesis monooxygenase domain CAK77_RS08180 8676b2ccba4fa710c1f6ada5a5b07ab1 384 SUPERFAMILY SSF51905 4 167 6.11E-52 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS08180 8676b2ccba4fa710c1f6ada5a5b07ab1 384 SUPERFAMILY SSF51905 259 353 6.11E-52 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS08180 8676b2ccba4fa710c1f6ada5a5b07ab1 384 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 3.2E-16 T 06-07-2017 CAK77_RS08180 8676b2ccba4fa710c1f6ada5a5b07ab1 384 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 287 303 3.2E-16 T 06-07-2017 CAK77_RS08180 8676b2ccba4fa710c1f6ada5a5b07ab1 384 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 272 287 3.2E-16 T 06-07-2017 CAK77_RS08180 8676b2ccba4fa710c1f6ada5a5b07ab1 384 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 146 161 3.2E-16 T 06-07-2017 CAK77_RS08180 8676b2ccba4fa710c1f6ada5a5b07ab1 384 Gene3D G3DSA:3.50.50.60 260 339 2.5E-35 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS08180 8676b2ccba4fa710c1f6ada5a5b07ab1 384 Gene3D G3DSA:3.50.50.60 4 172 2.5E-35 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS08180 8676b2ccba4fa710c1f6ada5a5b07ab1 384 Pfam PF01494 FAD binding domain 5 310 6.8E-18 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 CAK77_RS15325 230bc9b26ecffc7f9855f6a37ff77337 188 SUPERFAMILY SSF46689 6 82 2.77E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS15325 230bc9b26ecffc7f9855f6a37ff77337 188 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 55 1.8E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS15325 230bc9b26ecffc7f9855f6a37ff77337 188 Gene3D G3DSA:1.10.357.10 8 161 2.5E-19 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS03265 bf73097af3a569b2a9db0a671dca4fba 108 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 11 98 1.1E-19 T 06-07-2017 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:0015992 CAK77_RS03265 bf73097af3a569b2a9db0a671dca4fba 108 Pfam PF03334 Na+/H+ antiporter subunit 12 91 3.2E-22 T 06-07-2017 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:0015992 CAK77_RS10175 e2460e26dd61d12720b29deb06af7d5d 178 Pfam PF01966 HD domain 23 142 9.5E-10 T 06-07-2017 IPR006674 HD domain CAK77_RS10175 e2460e26dd61d12720b29deb06af7d5d 178 Gene3D G3DSA:1.10.3210.10 13 100 4.0E-12 T 06-07-2017 IPR006674 HD domain CAK77_RS10175 e2460e26dd61d12720b29deb06af7d5d 178 SUPERFAMILY SSF109604 10 97 9.95E-13 T 06-07-2017 CAK77_RS20215 223b2bb30b9a12e900819845e75b9314 358 Pfam PF02470 MlaD protein 36 110 2.1E-12 T 06-07-2017 IPR003399 Mce/MlaD CAK77_RS02730 cf40663c860ac94d28e11af0a14a3585 202 Pfam PF04402 Protein of unknown function (DUF541) 4 199 4.0E-40 T 06-07-2017 IPR007497 Protein of unknown function DUF541 CAK77_RS13300 936f3974bc2282a927165434fcca845b 122 Pfam PF13564 DoxX-like family 13 105 8.2E-10 T 06-07-2017 IPR032808 DoxX family CAK77_RS10900 162f8b81151e503bcb86788a6c44d47e 103 Pfam PF00106 short chain dehydrogenase 11 95 4.3E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS10900 162f8b81151e503bcb86788a6c44d47e 103 SUPERFAMILY SSF51735 9 97 3.05E-13 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS10900 162f8b81151e503bcb86788a6c44d47e 103 Gene3D G3DSA:3.40.50.720 11 97 2.0E-12 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS20160 8f1313bf436f73d2e531a90ebaba3a45 523 SUPERFAMILY SSF51905 20 249 8.01E-50 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS20160 8f1313bf436f73d2e531a90ebaba3a45 523 SUPERFAMILY SSF51905 310 432 8.01E-50 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS20160 8f1313bf436f73d2e531a90ebaba3a45 523 Gene3D G3DSA:3.50.50.60 320 495 1.1E-9 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS20160 8f1313bf436f73d2e531a90ebaba3a45 523 Gene3D G3DSA:3.50.50.60 12 220 2.7E-54 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS20160 8f1313bf436f73d2e531a90ebaba3a45 523 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 19 229 3.9E-14 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS13380 e284d9e95ebbee9b751ad01ba3b5891e 190 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 2.3E-15 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS13380 e284d9e95ebbee9b751ad01ba3b5891e 190 Gene3D G3DSA:1.10.10.60 10 55 4.0E-19 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS13380 e284d9e95ebbee9b751ad01ba3b5891e 190 SUPERFAMILY SSF46689 3 72 3.33E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS13380 e284d9e95ebbee9b751ad01ba3b5891e 190 SUPERFAMILY SSF48498 99 186 1.6E-7 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS13380 e284d9e95ebbee9b751ad01ba3b5891e 190 Gene3D G3DSA:1.10.357.10 56 174 2.1E-10 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS13380 e284d9e95ebbee9b751ad01ba3b5891e 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 8.7E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS13380 e284d9e95ebbee9b751ad01ba3b5891e 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 8.7E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS23690 e5c99990d85a5fafb5ff65d365851100 207 SMART SM00849 23 186 2.8E-37 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK77_RS23690 e5c99990d85a5fafb5ff65d365851100 207 SUPERFAMILY SSF56281 12 199 3.66E-45 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK77_RS23690 e5c99990d85a5fafb5ff65d365851100 207 Gene3D G3DSA:3.60.15.10 23 196 3.1E-45 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK77_RS23690 e5c99990d85a5fafb5ff65d365851100 207 Pfam PF00753 Metallo-beta-lactamase superfamily 24 186 9.2E-23 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK77_RS17170 8e0e3f107db77bbfffeb530b63c4e3a8 99 Pfam PF02467 Transcription factor WhiB 18 87 1.8E-20 T 06-07-2017 IPR003482 Transcription factor WhiB CAK77_RS17170 8e0e3f107db77bbfffeb530b63c4e3a8 99 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 16 92 15.92 T 06-07-2017 IPR003482 Transcription factor WhiB CAK77_RS05780 eaa6d41f9600cc4a513a5c481982b087 213 Pfam PF04977 Septum formation initiator 84 160 7.8E-18 T 06-07-2017 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 CAK77_RS06710 20e3c2e1309b47b416a60382343370f1 399 Pfam PF07690 Major Facilitator Superfamily 42 361 7.7E-19 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK77_RS06710 20e3c2e1309b47b416a60382343370f1 399 Gene3D G3DSA:1.20.1250.20 223 397 1.3E-21 T 06-07-2017 CAK77_RS06710 20e3c2e1309b47b416a60382343370f1 399 Gene3D G3DSA:1.20.1250.20 30 201 4.5E-15 T 06-07-2017 CAK77_RS06710 20e3c2e1309b47b416a60382343370f1 399 SUPERFAMILY SSF103473 21 396 1.14E-45 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK77_RS18445 939f5cc61d6ea97366d20b39e03b2f57 190 SUPERFAMILY SSF48498 74 185 2.62E-13 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS18445 939f5cc61d6ea97366d20b39e03b2f57 190 Gene3D G3DSA:1.10.357.10 7 181 1.2E-24 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS18445 939f5cc61d6ea97366d20b39e03b2f57 190 SUPERFAMILY SSF46689 2 79 3.33E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS18445 939f5cc61d6ea97366d20b39e03b2f57 190 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 56 7.1E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS04485 e12ec9c0195a6e4196147cb9378f5581 160 Pfam PF05481 Mycobacterium 19 kDa lipoprotein antigen 5 159 4.8E-36 T 06-07-2017 IPR008691 19kDa lipoprotein antigen GO:0016020 CAK77_RS02055 d5c0f6afecb71a297d3e6297d7747f4b 80 Gene3D G3DSA:1.10.10.60 44 71 7.5E-5 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS02055 d5c0f6afecb71a297d3e6297d7747f4b 80 Pfam PF13384 Homeodomain-like domain 41 76 8.9E-6 T 06-07-2017 CAK77_RS19720 43f0ebf412a111ef856a1a8990084ac2 233 SUPERFAMILY SSF81923 87 213 1.86E-15 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 CAK77_RS19720 43f0ebf412a111ef856a1a8990084ac2 233 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 110 141 3.1E-4 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 CAK77_RS19720 43f0ebf412a111ef856a1a8990084ac2 233 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 178 225 8.5E-8 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 CAK77_RS19720 43f0ebf412a111ef856a1a8990084ac2 233 Gene3D G3DSA:1.10.1780.10 84 225 6.6E-23 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 CAK77_RS15350 1e1c2859864d8fd50043a5fcec63572f 563 SUPERFAMILY SSF56281 20 435 1.31E-89 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK77_RS15350 1e1c2859864d8fd50043a5fcec63572f 563 PIRSF PIRSF004803 14 562 1.8E-183 T 06-07-2017 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 CAK77_RS15350 1e1c2859864d8fd50043a5fcec63572f 563 Gene3D G3DSA:3.60.15.10 19 266 5.0E-71 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK77_RS15350 1e1c2859864d8fd50043a5fcec63572f 563 Hamap MF_01491 Ribonuclease J [rnj]. 15 562 38.481 T 06-07-2017 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 CAK77_RS15350 1e1c2859864d8fd50043a5fcec63572f 563 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 21 559 9.0E-134 T 06-07-2017 IPR004613 Ribonuclease J GO:0003723|GO:0046872 CAK77_RS15350 1e1c2859864d8fd50043a5fcec63572f 563 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 373 418 3.8E-9 T 06-07-2017 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain CAK77_RS15350 1e1c2859864d8fd50043a5fcec63572f 563 Pfam PF12706 Beta-lactamase superfamily domain 71 177 1.3E-10 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK77_RS15350 1e1c2859864d8fd50043a5fcec63572f 563 SMART SM00849 32 226 6.0E-23 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK77_RS06665 1313c007be2068fa5d502ae0476efec0 655 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 74 227 2.2E-29 T 06-07-2017 CAK77_RS13115 e03e06d7de39de8257b5be2a7d0aee15 231 Gene3D G3DSA:3.90.79.10 8 137 1.9E-25 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAK77_RS13115 e03e06d7de39de8257b5be2a7d0aee15 231 Pfam PF00293 NUDIX domain 25 126 4.6E-8 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 CAK77_RS13115 e03e06d7de39de8257b5be2a7d0aee15 231 Gene3D G3DSA:1.10.10.10 143 224 1.8E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS13115 e03e06d7de39de8257b5be2a7d0aee15 231 SUPERFAMILY SSF46785 149 222 1.2E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS13115 e03e06d7de39de8257b5be2a7d0aee15 231 SUPERFAMILY SSF55811 26 145 1.62E-23 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAK77_RS17160 9d1e7ba38f9ae3417fca9bdd84624f82 120 Pfam PF06282 Protein of unknown function (DUF1036) 4 71 3.7E-8 T 06-07-2017 IPR009380 Protein of unknown function DUF1036 CAK77_RS20710 e49a1433601bdbe9226fb6421b90c242 145 Pfam PF04075 Domain of unknown function (DUF385) 30 98 2.4E-4 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CAK77_RS01975 1cb17b2c08fc9259d997685073fd9134 402 Pfam PF10110 Membrane domain of glycerophosphoryl diester phosphodiesterase 236 346 3.3E-7 T 06-07-2017 IPR018476 Glycerophosphoryl diester phosphodiesterase, membrane domain CAK77_RS02745 f33d0f16e95f31d679b53ccfd5696d63 397 Gene3D G3DSA:3.20.20.30 7 354 2.0E-74 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS02745 f33d0f16e95f31d679b53ccfd5696d63 397 SUPERFAMILY SSF51679 6 355 2.94E-71 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS02745 f33d0f16e95f31d679b53ccfd5696d63 397 Pfam PF00296 Luciferase-like monooxygenase 7 315 4.1E-38 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS00155 977fb29d7065fa6a270f118b6c51b725 45 Gene3D G3DSA:1.10.260.40 17 42 5.0E-6 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK77_RS00155 977fb29d7065fa6a270f118b6c51b725 45 SUPERFAMILY SSF47413 18 43 4.28E-5 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK77_RS02435 977fb29d7065fa6a270f118b6c51b725 45 Gene3D G3DSA:1.10.260.40 17 42 5.0E-6 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK77_RS02435 977fb29d7065fa6a270f118b6c51b725 45 SUPERFAMILY SSF47413 18 43 4.28E-5 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK77_RS02860 061ec24e5b1c21e4ef487af578d74e38 68 Pfam PF09489 Probable cobalt transporter subunit (CbtB) 17 68 1.4E-16 T 06-07-2017 IPR012667 Cobalt transporter subunit CbtB, putative CAK77_RS19735 ee29ac94094b3889c41bea7e928004a0 338 Pfam PF05726 Pirin C-terminal cupin domain 197 295 4.8E-14 T 06-07-2017 IPR008778 Pirin, C-terminal domain CAK77_RS19735 ee29ac94094b3889c41bea7e928004a0 338 SUPERFAMILY SSF51182 44 309 1.41E-62 T 06-07-2017 IPR011051 RmlC-like cupin domain CAK77_RS19735 ee29ac94094b3889c41bea7e928004a0 338 Pfam PF02678 Pirin 47 145 1.1E-29 T 06-07-2017 IPR003829 Pirin, N-terminal domain CAK77_RS19735 ee29ac94094b3889c41bea7e928004a0 338 PIRSF PIRSF006232 23 308 6.6E-76 T 06-07-2017 IPR012093 Pirin CAK77_RS19735 ee29ac94094b3889c41bea7e928004a0 338 Gene3D G3DSA:2.60.120.10 35 271 9.6E-56 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK77_RS21825 1424b3d2573c296e9fb17343af168c55 312 PRINTS PR00111 Alpha/beta hydrolase fold signature 112 125 2.3E-7 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS21825 1424b3d2573c296e9fb17343af168c55 312 PRINTS PR00111 Alpha/beta hydrolase fold signature 242 256 2.3E-7 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS21825 1424b3d2573c296e9fb17343af168c55 312 PRINTS PR00111 Alpha/beta hydrolase fold signature 66 81 2.3E-7 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS21825 1424b3d2573c296e9fb17343af168c55 312 Gene3D G3DSA:3.40.50.1820 15 297 3.3E-48 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS21825 1424b3d2573c296e9fb17343af168c55 312 Pfam PF12697 Alpha/beta hydrolase family 40 289 4.4E-21 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS21825 1424b3d2573c296e9fb17343af168c55 312 SUPERFAMILY SSF53474 14 296 6.91E-47 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS23170 b8b18c875c864b98001f80e7081e51bb 310 Pfam PF00149 Calcineurin-like phosphoesterase 53 244 5.7E-11 T 06-07-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 CAK77_RS23170 b8b18c875c864b98001f80e7081e51bb 310 SUPERFAMILY SSF56300 50 269 3.23E-43 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAK77_RS23170 b8b18c875c864b98001f80e7081e51bb 310 Gene3D G3DSA:3.60.21.10 50 272 4.8E-31 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAK77_RS19400 a2b7d25b3329c7e71f0dbe3296333f66 314 Pfam PF04072 Leucine carboxyl methyltransferase 19 205 7.0E-55 T 06-07-2017 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 CAK77_RS19400 a2b7d25b3329c7e71f0dbe3296333f66 314 Gene3D G3DSA:3.40.50.150 15 220 3.3E-13 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS19400 a2b7d25b3329c7e71f0dbe3296333f66 314 SUPERFAMILY SSF53335 15 311 4.71E-75 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS19400 a2b7d25b3329c7e71f0dbe3296333f66 314 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 17 292 3.9E-79 T 06-07-2017 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 CAK77_RS05460 f3779f6539f6433c7e074c815e65c462 309 Pfam PF00483 Nucleotidyl transferase 12 277 1.3E-28 T 06-07-2017 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CAK77_RS05460 f3779f6539f6433c7e074c815e65c462 309 Gene3D G3DSA:3.90.550.10 10 282 7.6E-60 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK77_RS05460 f3779f6539f6433c7e074c815e65c462 309 SUPERFAMILY SSF53448 11 288 3.6E-54 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK77_RS18440 fb913263f0c8c11a38873b4509b0af09 348 Gene3D G3DSA:3.40.50.1820 275 347 9.7E-46 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS18440 fb913263f0c8c11a38873b4509b0af09 348 Gene3D G3DSA:3.40.50.1820 18 167 9.7E-46 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS18440 fb913263f0c8c11a38873b4509b0af09 348 SUPERFAMILY SSF53474 15 166 2.2E-42 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS18440 fb913263f0c8c11a38873b4509b0af09 348 SUPERFAMILY SSF53474 242 347 2.2E-42 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS00900 5cdc2476c8a8f0fc79d58bec1798643d 247 Pfam PF14011 EspG family 8 242 2.3E-49 T 06-07-2017 IPR025734 EspG family CAK77_RS09650 b0f7eb05ddddc979f637ab4ea8cb6cfe 432 Pfam PF09594 Protein of unknown function (DUF2029) 84 314 1.5E-38 T 06-07-2017 IPR018584 Glycosyltransferase family 87 GO:0016758 CAK77_RS22020 c5a81a5378ebbef7cfb47ff0571f9631 463 ProSitePatterns PS00571 Amidases signature. 157 188 - T 06-07-2017 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 CAK77_RS22020 c5a81a5378ebbef7cfb47ff0571f9631 463 SUPERFAMILY SSF75304 4 460 2.49E-131 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAK77_RS22020 c5a81a5378ebbef7cfb47ff0571f9631 463 Gene3D G3DSA:3.90.1300.10 5 461 1.5E-129 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAK77_RS22020 c5a81a5378ebbef7cfb47ff0571f9631 463 Pfam PF01425 Amidase 28 451 1.1E-103 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAK77_RS12970 91ad3c803117fb9612935606100238f8 469 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 139 437 8.2E-63 T 06-07-2017 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal CAK77_RS06715 a43a06cddf5c5aa04cb3fc9bc23af4ea 312 TIGRFAM TIGR03564 F420_MSMEG_4879: F420-dependent oxidoreductase, MSMEG_4879 family 24 286 8.5E-104 T 06-07-2017 IPR019910 Luciferase-like, F420-dependent oxidoreductase, MSMEG4879, predicted CAK77_RS06715 a43a06cddf5c5aa04cb3fc9bc23af4ea 312 Pfam PF00296 Luciferase-like monooxygenase 19 296 2.1E-42 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS06715 a43a06cddf5c5aa04cb3fc9bc23af4ea 312 Gene3D G3DSA:3.20.20.30 6 307 5.3E-48 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS06715 a43a06cddf5c5aa04cb3fc9bc23af4ea 312 SUPERFAMILY SSF51679 20 307 2.62E-47 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS04260 d92c198c2d628953f9d777db82b30db9 151 SUPERFAMILY SSF50249 9 140 3.43E-18 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS10105 88dacf4a394b379ca929c0c3a9dedaf6 352 Pfam PF14399 Butirosin biosynthesis protein H, N-terminal 15 149 5.3E-44 T 06-07-2017 IPR026935 Butirosin biosynthesis protein H, N-terminal KEGG: 00524+2.3.2.19|MetaCyc: PWY-7019 CAK77_RS10105 88dacf4a394b379ca929c0c3a9dedaf6 352 Pfam PF16169 Domain of unknown function (DUF4872) 160 344 8.8E-48 T 06-07-2017 IPR032369 Domain of unknown function DUF4872 CAK77_RS04430 63dbe43d620fc0e5b5c9023897a7f62d 251 SUPERFAMILY SSF48371 25 239 2.27E-30 T 06-07-2017 IPR016024 Armadillo-type fold GO:0005488 CAK77_RS04430 63dbe43d620fc0e5b5c9023897a7f62d 251 Pfam PF08713 DNA alkylation repair enzyme 21 239 1.5E-51 T 06-07-2017 IPR014825 DNA alkylation repair enzyme CAK77_RS04430 63dbe43d620fc0e5b5c9023897a7f62d 251 Gene3D G3DSA:1.25.40.290 150 240 3.6E-15 T 06-07-2017 CAK77_RS03045 01215262046b19352fcc6c7fbca38138 418 Gene3D G3DSA:2.60.120.580 156 173 3.8E-61 T 06-07-2017 CAK77_RS03045 01215262046b19352fcc6c7fbca38138 418 Gene3D G3DSA:2.60.120.580 8 95 3.8E-61 T 06-07-2017 CAK77_RS03045 01215262046b19352fcc6c7fbca38138 418 Gene3D G3DSA:2.60.120.580 222 290 3.8E-61 T 06-07-2017 CAK77_RS03045 01215262046b19352fcc6c7fbca38138 418 Pfam PF03069 Acetamidase/Formamidase family 9 394 8.7E-165 T 06-07-2017 IPR004304 Acetamidase/Formamidase GO:0016811 CAK77_RS03045 01215262046b19352fcc6c7fbca38138 418 SUPERFAMILY SSF141130 21 173 1.44E-72 T 06-07-2017 CAK77_RS03045 01215262046b19352fcc6c7fbca38138 418 SUPERFAMILY SSF141130 222 393 1.44E-72 T 06-07-2017 CAK77_RS03045 01215262046b19352fcc6c7fbca38138 418 Gene3D G3DSA:3.10.28.20 336 393 4.9E-4 T 06-07-2017 CAK77_RS16630 f2d8326da8b07f3792ee67b5a8420841 621 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 63 225 1.9E-24 T 06-07-2017 CAK77_RS07595 515ec0d3ff1ddd12d03962675063a4e4 583 Pfam PF15420 Alpha/beta-hydrolase family N-terminus 64 270 1.4E-68 T 06-07-2017 IPR027788 Alpha/beta-hydrolase, N-terminal domain CAK77_RS07595 515ec0d3ff1ddd12d03962675063a4e4 583 PIRSF PIRSF007542 10 583 1.3E-214 T 06-07-2017 IPR012037 Alpha/beta-hydrolase family CAK77_RS07595 515ec0d3ff1ddd12d03962675063a4e4 583 Pfam PF10081 Alpha/beta-hydrolase family 288 575 2.7E-131 T 06-07-2017 IPR027787 Alpha/beta-hydrolase, catalytic domain CAK77_RS05935 a864a660c13df037f03b22d91e30ebdc 190 SUPERFAMILY SSF51182 36 182 2.97E-25 T 06-07-2017 IPR011051 RmlC-like cupin domain CAK77_RS05935 a864a660c13df037f03b22d91e30ebdc 190 Gene3D G3DSA:2.60.120.10 61 171 9.0E-14 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAK77_RS05935 a864a660c13df037f03b22d91e30ebdc 190 Pfam PF05995 Cysteine dioxygenase type I 61 167 1.4E-11 T 06-07-2017 IPR010300 Cysteine dioxygenase type I GO:0005506|GO:0016702|GO:0055114 KEGG: 00270+1.13.11.20|KEGG: 00430+1.13.11.20|MetaCyc: PWY-5331|Reactome: R-HSA-1614558 CAK77_RS18260 7fc0f35879ef9fc67c29681b04710e0f 113 SUPERFAMILY SSF82607 33 111 1.7E-7 T 06-07-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family CAK77_RS18260 7fc0f35879ef9fc67c29681b04710e0f 113 Gene3D G3DSA:3.30.1310.10 14 111 3.3E-7 T 06-07-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family CAK77_RS18260 7fc0f35879ef9fc67c29681b04710e0f 113 Pfam PF02575 YbaB/EbfC DNA-binding family 31 105 4.4E-7 T 06-07-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family CAK77_RS02640 1401b3a3985fd832810a4fb6cb3b6ef4 232 Pfam PF00535 Glycosyl transferase family 2 11 166 5.1E-23 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CAK77_RS02640 1401b3a3985fd832810a4fb6cb3b6ef4 232 SUPERFAMILY SSF53448 8 213 1.03E-28 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK77_RS02640 1401b3a3985fd832810a4fb6cb3b6ef4 232 Gene3D G3DSA:3.90.550.10 11 120 9.4E-12 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK77_RS22835 fcb7060887f3bcd712b02378227d08de 252 Gene3D G3DSA:3.90.226.10 3 193 2.9E-60 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS22835 fcb7060887f3bcd712b02378227d08de 252 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 251 1.3E-53 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAK77_RS22835 fcb7060887f3bcd712b02378227d08de 252 Gene3D G3DSA:1.10.12.10 196 252 1.6E-19 T 06-07-2017 IPR014748 Crontonase, C-terminal CAK77_RS22835 fcb7060887f3bcd712b02378227d08de 252 SUPERFAMILY SSF52096 2 251 2.4E-79 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS22835 fcb7060887f3bcd712b02378227d08de 252 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 93 113 - T 06-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CAK77_RS12735 f0220db985fe86c8dd1138f0860f54d5 321 Pfam PF09678 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) 34 268 3.8E-52 T 06-07-2017 IPR019108 Cytochrome c oxidase caa3-type, assembly factor CtaG-related CAK77_RS02355 129e036679e46adb8f3eab16f7e04535 539 PIRSF PIRSF002741 20 535 2.5E-67 T 06-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CAK77_RS02355 129e036679e46adb8f3eab16f7e04535 539 SUPERFAMILY SSF53850 29 535 1.3E-92 T 06-07-2017 CAK77_RS02355 129e036679e46adb8f3eab16f7e04535 539 Gene3D G3DSA:3.10.105.10 308 508 9.4E-46 T 06-07-2017 CAK77_RS02355 129e036679e46adb8f3eab16f7e04535 539 Gene3D G3DSA:3.40.190.10 157 307 1.7E-29 T 06-07-2017 CAK77_RS02355 129e036679e46adb8f3eab16f7e04535 539 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 80 452 1.2E-58 T 06-07-2017 IPR000914 Solute-binding protein family 5 domain CAK77_RS14225 dcf4df90895817595e0f4d080ac5b2c7 363 Pfam PF00501 AMP-binding enzyme 194 313 2.7E-5 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK77_RS14225 dcf4df90895817595e0f4d080ac5b2c7 363 SUPERFAMILY SSF56801 52 314 3.26E-14 T 06-07-2017 CAK77_RS11000 132d15d3b9c27c52cc7c63724425e032 463 Pfam PF07690 Major Facilitator Superfamily 56 399 3.1E-37 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK77_RS11000 132d15d3b9c27c52cc7c63724425e032 463 SUPERFAMILY SSF103473 15 443 2.49E-72 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK77_RS11000 132d15d3b9c27c52cc7c63724425e032 463 Gene3D G3DSA:1.20.1250.20 28 241 4.9E-28 T 06-07-2017 CAK77_RS11000 132d15d3b9c27c52cc7c63724425e032 463 Gene3D G3DSA:1.20.1250.20 253 438 6.3E-24 T 06-07-2017 CAK77_RS11000 132d15d3b9c27c52cc7c63724425e032 463 ProSitePatterns PS00217 Sugar transport proteins signature 2. 139 164 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CAK77_RS15300 a5b0e98d454bcc49c31ae56278da173d 218 Gene3D G3DSA:1.20.1290.10 44 187 4.9E-31 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAK77_RS15300 a5b0e98d454bcc49c31ae56278da173d 218 SUPERFAMILY SSF69118 1 187 4.68E-36 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAK77_RS15300 a5b0e98d454bcc49c31ae56278da173d 218 Pfam PF02627 Carboxymuconolactone decarboxylase family 66 134 3.8E-11 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CAK77_RS05785 b9146f42201d2ba0d1ba122e7e2ac6b5 160 Pfam PF04417 Protein of unknown function (DUF501) 24 143 2.0E-33 T 06-07-2017 IPR007511 Protein of unknown function DUF501 CAK77_RS04480 42e0c67ae17ba440e43b088a9bbdf671 270 Pfam PF11268 Protein of unknown function (DUF3071) 1 169 3.3E-59 T 06-07-2017 IPR021421 Protein of unknown function DUF3071 CAK77_RS07735 d0c6689c886a3b796e11219d34d180b3 316 Pfam PF11583 P-aminobenzoate N-oxygenase AurF 14 283 5.2E-73 T 06-07-2017 IPR025859 P-aminobenzoate N-oxygenase AurF CAK77_RS07735 d0c6689c886a3b796e11219d34d180b3 316 SUPERFAMILY SSF47240 85 242 2.64E-8 T 06-07-2017 IPR009078 Ferritin-like superfamily CAK77_RS11055 8c2f5cd85ce7b1e2dc77dcf8d233ed6b 125 Pfam PF13564 DoxX-like family 12 109 2.4E-7 T 06-07-2017 IPR032808 DoxX family CAK77_RS19570 6c5ecf5e81e2ad439d1fee60bc6e1d15 493 Gene3D G3DSA:3.40.390.10 239 337 6.5E-10 T 06-07-2017 IPR024079 Metallopeptidase, catalytic domain GO:0008237 CAK77_RS19570 6c5ecf5e81e2ad439d1fee60bc6e1d15 493 SUPERFAMILY SSF55486 238 336 8.6E-9 T 06-07-2017 CAK77_RS03485 d4fedbbd15079027130bd0e96775cc75 134 Pfam PF13392 HNH endonuclease 78 102 1.4E-6 T 06-07-2017 IPR003615 HNH nuclease CAK77_RS04160 17d4575805f1df156994eb755dbd89fc 69 SUPERFAMILY SSF50692 6 53 9.72E-8 T 06-07-2017 IPR009010 Aspartate decarboxylase-like domain CAK77_RS04160 17d4575805f1df156994eb755dbd89fc 69 Gene3D G3DSA:2.40.40.20 6 52 1.1E-5 T 06-07-2017 CAK77_RS06050 6bcead39cd0ad78b1b1cc897abc175f2 658 Pfam PF03190 Protein of unknown function, DUF255 4 159 1.6E-70 T 06-07-2017 IPR004879 Domain of unknown function DUF255 CAK77_RS06050 6bcead39cd0ad78b1b1cc897abc175f2 658 SUPERFAMILY SSF52833 4 137 1.32E-28 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK77_RS06050 6bcead39cd0ad78b1b1cc897abc175f2 658 Gene3D G3DSA:3.40.30.10 21 142 3.6E-33 T 06-07-2017 IPR012336 Thioredoxin-like fold CAK77_RS06050 6bcead39cd0ad78b1b1cc897abc175f2 658 SUPERFAMILY SSF48208 187 523 2.31E-66 T 06-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 CAK77_RS06050 6bcead39cd0ad78b1b1cc897abc175f2 658 PIRSF PIRSF006402 1 658 2.9E-190 T 06-07-2017 IPR024705 Spermatogenesis-associated protein 20 CAK77_RS06050 6bcead39cd0ad78b1b1cc897abc175f2 658 Gene3D G3DSA:1.50.10.10 209 515 8.6E-16 T 06-07-2017 IPR012341 Six-hairpin glycosidase GO:0003824 CAK77_RS12655 e348ba455af0e206506fed9af53ca1fb 485 SUPERFAMILY SSF56349 260 437 2.21E-9 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CAK77_RS12655 e348ba455af0e206506fed9af53ca1fb 485 Gene3D G3DSA:1.10.443.10 318 436 1.0E-6 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAK77_RS02735 06132a554b3a4cb28fd2b2713b073e3c 249 Pfam PF04402 Protein of unknown function (DUF541) 42 246 7.0E-50 T 06-07-2017 IPR007497 Protein of unknown function DUF541 CAK77_RS15370 d6ad0cf35c7ee461c8e78dfd44f83d16 407 Pfam PF06224 Winged helix DNA-binding domain 38 367 1.2E-75 T 06-07-2017 IPR009351 Protein of unknown function DUF1006 CAK77_RS13265 172c33949cc91facd88ae945469a881e 350 Pfam PF03445 Putative nucleotidyltransferase DUF294 45 163 1.2E-14 T 06-07-2017 IPR005105 Protein-PII uridylyltransferase, N-terminal GO:0008773 CAK77_RS13265 172c33949cc91facd88ae945469a881e 350 Gene3D G3DSA:3.30.460.10 81 115 4.0E-5 T 06-07-2017 CAK77_RS13265 172c33949cc91facd88ae945469a881e 350 Pfam PF10335 Putative nucleotidyltransferase substrate binding domain 214 340 5.1E-23 T 06-07-2017 IPR018821 Domain of unknown function DUF294, putative nucleotidyltransferase substrate-binding CAK77_RS12195 1ad760d344efed3b4c8a5b9ce816585c 335 Gene3D G3DSA:1.20.910.10 105 328 3.0E-59 T 06-07-2017 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CAK77_RS12195 1ad760d344efed3b4c8a5b9ce816585c 335 SUPERFAMILY SSF48613 130 306 1.93E-12 T 06-07-2017 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CAK77_RS12195 1ad760d344efed3b4c8a5b9ce816585c 335 Pfam PF14518 Iron-containing redox enzyme 136 306 3.7E-43 T 06-07-2017 IPR028201 PqqC-like protein CAK77_RS12195 1ad760d344efed3b4c8a5b9ce816585c 335 SMART SM01236 168 273 2.4E-35 T 06-07-2017 CAK77_RS23455 e25907bc63fc55583d87077f7f3cf990 300 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 222 265 - T 06-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CAK77_RS23455 e25907bc63fc55583d87077f7f3cf990 300 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 171 211 - T 06-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CAK77_RS23455 e25907bc63fc55583d87077f7f3cf990 300 SUPERFAMILY SSF46689 219 269 6.72E-6 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS23455 e25907bc63fc55583d87077f7f3cf990 300 Gene3D G3DSA:1.10.10.60 166 219 3.4E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS23455 e25907bc63fc55583d87077f7f3cf990 300 Gene3D G3DSA:1.10.10.60 220 268 1.9E-7 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS23455 e25907bc63fc55583d87077f7f3cf990 300 SMART SM00342 182 269 5.4E-15 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK77_RS23455 e25907bc63fc55583d87077f7f3cf990 300 Pfam PF12833 Helix-turn-helix domain 188 270 2.0E-17 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAK77_RS14780 30c90e36633fd814fe6801cd2c9b2b14 164 SUPERFAMILY SSF81982 40 155 1.83E-5 T 06-07-2017 IPR015250 MPT63-like GO:0005615 CAK77_RS14780 30c90e36633fd814fe6801cd2c9b2b14 164 Gene3D G3DSA:2.60.40.1240 36 153 5.8E-4 T 06-07-2017 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain CAK77_RS16240 1a77a016dfa1285b846acb667481fd08 304 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 1 238 1.6E-37 T 06-07-2017 IPR018713 Domain of unknown function DUF2236 CAK77_RS11895 38fe5be2787f5d7909a55b1400ca9756 290 Gene3D G3DSA:3.20.20.30 8 288 8.1E-56 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS11895 38fe5be2787f5d7909a55b1400ca9756 290 SUPERFAMILY SSF51679 7 285 1.7E-49 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS11895 38fe5be2787f5d7909a55b1400ca9756 290 Pfam PF00296 Luciferase-like monooxygenase 10 222 6.8E-43 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS11305 4dbd390de525b49616efd348c8c08eb1 129 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 27.544 T 06-07-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS11305 4dbd390de525b49616efd348c8c08eb1 129 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 21 61 6.0E-17 T 06-07-2017 CAK77_RS11305 4dbd390de525b49616efd348c8c08eb1 129 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 114 6.8E-42 T 06-07-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS11305 4dbd390de525b49616efd348c8c08eb1 129 Gene3D G3DSA:1.10.1900.20 56 118 1.6E-28 T 06-07-2017 CAK77_RS11305 4dbd390de525b49616efd348c8c08eb1 129 SUPERFAMILY SSF74731 3 117 4.19E-43 T 06-07-2017 CAK77_RS11305 4dbd390de525b49616efd348c8c08eb1 129 PRINTS PR00062 Ribosomal protein L20 signature 75 101 3.8E-37 T 06-07-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS11305 4dbd390de525b49616efd348c8c08eb1 129 PRINTS PR00062 Ribosomal protein L20 signature 12 41 3.8E-37 T 06-07-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS11305 4dbd390de525b49616efd348c8c08eb1 129 PRINTS PR00062 Ribosomal protein L20 signature 42 71 3.8E-37 T 06-07-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS11305 4dbd390de525b49616efd348c8c08eb1 129 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 06-07-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS11305 4dbd390de525b49616efd348c8c08eb1 129 Pfam PF00453 Ribosomal protein L20 3 109 4.2E-41 T 06-07-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS07855 c625a359c1fcde64abacc8441beab61a 669 Pfam PF09678 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) 385 630 2.2E-82 T 06-07-2017 IPR019108 Cytochrome c oxidase caa3-type, assembly factor CtaG-related CAK77_RS07855 c625a359c1fcde64abacc8441beab61a 669 Pfam PF05425 Copper resistance protein D 236 333 3.3E-20 T 06-07-2017 IPR008457 Copper resistance protein D GO:0016021 CAK77_RS15210 f85ea71503923c2868ae4a8ef4056845 295 Gene3D G3DSA:2.30.110.10 27 123 2.5E-7 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS15210 f85ea71503923c2868ae4a8ef4056845 295 Gene3D G3DSA:2.30.110.10 160 255 1.0E-9 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS15210 f85ea71503923c2868ae4a8ef4056845 295 SUPERFAMILY SSF50475 166 258 2.25E-6 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS15210 f85ea71503923c2868ae4a8ef4056845 295 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 161 254 4.7E-13 T 06-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAK77_RS15210 f85ea71503923c2868ae4a8ef4056845 295 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 33 117 1.9E-4 T 06-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAK77_RS10035 30095503183480b7ceceacd5c0db387f 533 Gene3D G3DSA:3.90.226.10 276 521 1.0E-74 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS10035 30095503183480b7ceceacd5c0db387f 533 Gene3D G3DSA:3.90.226.10 39 267 1.0E-56 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS10035 30095503183480b7ceceacd5c0db387f 533 Pfam PF01039 Carboxyl transferase domain 49 520 3.2E-127 T 06-07-2017 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAK77_RS10035 30095503183480b7ceceacd5c0db387f 533 SUPERFAMILY SSF52096 27 265 3.69E-59 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS10035 30095503183480b7ceceacd5c0db387f 533 SUPERFAMILY SSF52096 233 514 2.6E-74 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS06490 a55e48bfd6b874bf721c2ab5c086a4db 282 SUPERFAMILY SSF53335 23 256 4.98E-45 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS06490 a55e48bfd6b874bf721c2ab5c086a4db 282 Pfam PF04072 Leucine carboxyl methyltransferase 32 185 1.4E-11 T 06-07-2017 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 CAK77_RS06490 a55e48bfd6b874bf721c2ab5c086a4db 282 Gene3D G3DSA:3.40.50.150 24 200 5.3E-22 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS13965 0938278e8c9ce33c5da3a526e6d294c6 390 Gene3D G3DSA:3.90.1200.10 153 276 2.5E-4 T 06-07-2017 CAK77_RS13965 0938278e8c9ce33c5da3a526e6d294c6 390 SUPERFAMILY SSF56112 9 306 5.83E-16 T 06-07-2017 IPR011009 Protein kinase-like domain CAK77_RS08200 f403b7b2a9bcb95ad4b9825b6e093eda 145 Pfam PF14017 Protein of unknown function (DUF4233) 29 131 9.0E-27 T 06-07-2017 IPR025327 Protein of unknown function DUF4233 CAK77_RS22620 32ff599a75153eeb360cfc500048c996 578 SUPERFAMILY SSF143975 15 399 6.54E-136 T 06-07-2017 CAK77_RS22620 32ff599a75153eeb360cfc500048c996 578 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 486 497 - T 06-07-2017 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CAK77_RS22620 32ff599a75153eeb360cfc500048c996 578 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 22 578 45.609 T 06-07-2017 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CAK77_RS22620 32ff599a75153eeb360cfc500048c996 578 Pfam PF00920 Dehydratase family 52 575 4.8E-212 T 06-07-2017 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CAK77_RS22620 32ff599a75153eeb360cfc500048c996 578 SUPERFAMILY SSF52016 400 577 5.89E-56 T 06-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CAK77_RS22620 32ff599a75153eeb360cfc500048c996 578 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 140 150 - T 06-07-2017 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CAK77_RS22620 32ff599a75153eeb360cfc500048c996 578 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 36 576 3.5E-218 T 06-07-2017 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CAK77_RS01185 d3604611b4014ae0925cdca652b3978a 172 Pfam PF10759 Protein of unknown function (DUF2587) 29 160 2.3E-77 T 06-07-2017 IPR019695 Bacterial proteasome activator GO:0061136 CAK77_RS14220 3ce691eab80099ea917b57c012616666 454 Pfam PF00171 Aldehyde dehydrogenase family 44 385 2.7E-8 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAK77_RS14220 3ce691eab80099ea917b57c012616666 454 Gene3D G3DSA:3.40.605.10 22 284 2.9E-13 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAK77_RS14220 3ce691eab80099ea917b57c012616666 454 SUPERFAMILY SSF53720 16 440 1.23E-25 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAK77_RS18050 ea70b5eec4854cb5655ddc5d40a97f9a 185 SUPERFAMILY SSF54427 32 116 7.94E-6 T 06-07-2017 IPR032710 NTF2-like domain CAK77_RS06525 71c0c706fe426f94b22d8eba6d2ae694 194 Gene3D G3DSA:1.10.340.30 14 135 7.4E-13 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CAK77_RS06525 71c0c706fe426f94b22d8eba6d2ae694 194 TIGRFAM TIGR03252 TIGR03252: uncharacterized HhH-GPD family protein 4 190 1.3E-97 T 06-07-2017 IPR017658 Conserved hypothetical protein CHP03252, HhH-GPD CAK77_RS06525 71c0c706fe426f94b22d8eba6d2ae694 194 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 25 189 5.1E-19 T 06-07-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CAK77_RS06525 71c0c706fe426f94b22d8eba6d2ae694 194 SUPERFAMILY SSF48150 4 147 2.97E-14 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CAK77_RS11675 c1a492f4195bba8c5eae5d98060f6d35 167 SUPERFAMILY SSF103256 2 135 3.01E-46 T 06-07-2017 IPR003729 Bifunctional nuclease domain GO:0004518 CAK77_RS11675 c1a492f4195bba8c5eae5d98060f6d35 167 Pfam PF02577 Bifunctional nuclease 6 127 4.2E-46 T 06-07-2017 IPR003729 Bifunctional nuclease domain GO:0004518 CAK77_RS06535 d2b26f5f24e43d7e5e8459a44de90b7c 415 Pfam PF09594 Protein of unknown function (DUF2029) 90 316 1.9E-54 T 06-07-2017 IPR018584 Glycosyltransferase family 87 GO:0016758 CAK77_RS14875 c7d316f3d2ba8f7762958750a45e3444 540 Gene3D G3DSA:3.20.20.10 92 294 2.2E-56 T 06-07-2017 IPR029066 PLP-binding barrel CAK77_RS14875 c7d316f3d2ba8f7762958750a45e3444 540 Gene3D G3DSA:3.20.20.10 368 395 2.2E-56 T 06-07-2017 IPR029066 PLP-binding barrel CAK77_RS14875 c7d316f3d2ba8f7762958750a45e3444 540 Gene3D G3DSA:2.40.37.10 295 314 1.2E-26 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CAK77_RS14875 c7d316f3d2ba8f7762958750a45e3444 540 Gene3D G3DSA:2.40.37.10 396 538 1.2E-26 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CAK77_RS14875 c7d316f3d2ba8f7762958750a45e3444 540 SUPERFAMILY SSF51419 82 320 8.29E-50 T 06-07-2017 IPR029066 PLP-binding barrel CAK77_RS14875 c7d316f3d2ba8f7762958750a45e3444 540 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 97 316 2.0E-37 T 06-07-2017 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 CAK77_RS14875 c7d316f3d2ba8f7762958750a45e3444 540 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 115 133 1.2E-8 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CAK77_RS14875 c7d316f3d2ba8f7762958750a45e3444 540 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 392 411 1.2E-8 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CAK77_RS14875 c7d316f3d2ba8f7762958750a45e3444 540 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 135 147 1.2E-8 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CAK77_RS14875 c7d316f3d2ba8f7762958750a45e3444 540 SUPERFAMILY SSF50621 384 538 1.47E-18 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CAK77_RS14290 58484d22eea5976a525bca0f74fb8cf1 155 Gene3D G3DSA:1.10.260.40 48 117 1.2E-6 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK77_RS15295 d1361c7b42fa0b273f953fe033361e45 165 SUPERFAMILY SSF55729 1 119 3.09E-21 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS15295 d1361c7b42fa0b273f953fe033361e45 165 Pfam PF00583 Acetyltransferase (GNAT) family 43 114 2.2E-11 T 06-07-2017 IPR000182 GNAT domain GO:0008080 CAK77_RS15295 d1361c7b42fa0b273f953fe033361e45 165 Gene3D G3DSA:3.40.630.30 1 138 7.1E-29 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS23055 0d351cf20ac697f41b5fcd42ee01f2da 263 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 11 184 2.4E-4 T 06-07-2017 CAK77_RS23055 0d351cf20ac697f41b5fcd42ee01f2da 263 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 146 174 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAK77_RS23055 0d351cf20ac697f41b5fcd42ee01f2da 263 SUPERFAMILY SSF51735 9 252 8.65E-78 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS23055 0d351cf20ac697f41b5fcd42ee01f2da 263 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 250 8.3E-62 T 06-07-2017 CAK77_RS23055 0d351cf20ac697f41b5fcd42ee01f2da 263 Gene3D G3DSA:3.40.50.720 4 252 2.2E-82 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS23055 0d351cf20ac697f41b5fcd42ee01f2da 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 5.3E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS23055 0d351cf20ac697f41b5fcd42ee01f2da 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 5.3E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS23055 0d351cf20ac697f41b5fcd42ee01f2da 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 5.3E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS23055 0d351cf20ac697f41b5fcd42ee01f2da 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 5.3E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS23055 0d351cf20ac697f41b5fcd42ee01f2da 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 5.3E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS23055 0d351cf20ac697f41b5fcd42ee01f2da 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 5.3E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS23055 0d351cf20ac697f41b5fcd42ee01f2da 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 86 97 4.6E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS23055 0d351cf20ac697f41b5fcd42ee01f2da 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 4.6E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS23055 0d351cf20ac697f41b5fcd42ee01f2da 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 4.6E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAK77_RS16560 8a3a2ab1d5c37ef0a1e9682f21bb741a 564 PIRSF PIRSF006060 2 513 1.9E-48 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CAK77_RS16560 8a3a2ab1d5c37ef0a1e9682f21bb741a 564 Pfam PF13520 Amino acid permease 31 457 1.1E-27 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CAK77_RS19235 c559fcda32f2fd41161a16e21401977a 151 Pfam PF11259 Protein of unknown function (DUF3060) 86 144 4.3E-22 T 06-07-2017 IPR021417 Protein of unknown function DUF3060 CAK77_RS08095 4dc345e7781f09ce8cfd82d8441f62f2 207 Gene3D G3DSA:1.20.120.450 3 94 2.2E-9 T 06-07-2017 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase CAK77_RS08095 4dc345e7781f09ce8cfd82d8441f62f2 207 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 8 187 4.1E-31 T 06-07-2017 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type CAK77_RS08095 4dc345e7781f09ce8cfd82d8441f62f2 207 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 9 94 6.0E-14 T 06-07-2017 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 CAK77_RS08095 4dc345e7781f09ce8cfd82d8441f62f2 207 SUPERFAMILY SSF109854 3 126 8.24E-18 T 06-07-2017 CAK77_RS01395 11a020fdc3818cca2f26cd468c465e62 183 Pfam PF14231 GXWXG protein 22 78 9.9E-24 T 06-07-2017 IPR025951 GXWXG domain CAK77_RS01395 11a020fdc3818cca2f26cd468c465e62 183 Pfam PF14232 Domain of unknown function (DUF4334) 128 182 6.1E-27 T 06-07-2017 IPR025568 Domain of unknown function DUF4334 CAK77_RS06020 26ccdee1621adeebf9e5c93d5140a950 414 SUPERFAMILY SSF53686 14 325 1.15E-96 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAK77_RS06020 26ccdee1621adeebf9e5c93d5140a950 414 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 25 315 4.0E-81 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAK77_RS06020 26ccdee1621adeebf9e5c93d5140a950 414 TIGRFAM TIGR01127 ilvA_1Cterm: threonine ammonia-lyase 31 410 1.3E-124 T 06-07-2017 IPR005789 Threonine dehydratase, catabolic GO:0004794|GO:0006567 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 CAK77_RS06020 26ccdee1621adeebf9e5c93d5140a950 414 Gene3D G3DSA:3.40.50.1100 80 331 1.9E-74 T 06-07-2017 CAK77_RS00490 4430be2cbc9d18247a24cdba3fe360df 302 Pfam PF04116 Fatty acid hydroxylase superfamily 111 244 6.3E-19 T 06-07-2017 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0006633|GO:0016491|GO:0055114 CAK77_RS13815 de7fbf23e8d0ba66e0c921c881004bb7 438 Pfam PF01757 Acyltransferase family 15 338 4.6E-13 T 06-07-2017 IPR002656 Acyltransferase 3 GO:0016747 CAK77_RS03865 51f75cad1de8c224944dc428cd1177da 529 PIRSF PIRSF014677 10 522 1.4E-73 T 06-07-2017 IPR011202 Uncharacterised conserved protein UCP014677 CAK77_RS03865 51f75cad1de8c224944dc428cd1177da 529 Pfam PF13289 SIR2-like domain 140 251 1.0E-23 T 06-07-2017 CAK77_RS09675 579723473605f5c34e472e1afce550fe 134 Pfam PF12728 Helix-turn-helix domain 17 55 2.2E-6 T 06-07-2017 CAK77_RS24240 4176958335637f7a217a67b1543c07dd 277 Pfam PF14337 Domain of unknown function (DUF4393) 111 266 2.5E-23 T 06-07-2017 IPR025506 Protein of unknown function DUF4393 CAK77_RS24290 c15c2e5c12cf18bf9f62e73c367f80a7 1144 Gene3D G3DSA:2.60.120.260 1011 1140 1.8E-4 T 06-07-2017 IPR008979 Galactose-binding domain-like CAK77_RS24290 c15c2e5c12cf18bf9f62e73c367f80a7 1144 Pfam PF03023 MviN-like protein 51 489 3.7E-103 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ CAK77_RS24290 c15c2e5c12cf18bf9f62e73c367f80a7 1144 PRINTS PR01806 Virulence factor MviN signature 175 196 1.3E-15 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ CAK77_RS24290 c15c2e5c12cf18bf9f62e73c367f80a7 1144 PRINTS PR01806 Virulence factor MviN signature 287 313 1.3E-15 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ CAK77_RS24290 c15c2e5c12cf18bf9f62e73c367f80a7 1144 PRINTS PR01806 Virulence factor MviN signature 151 175 1.3E-15 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ CAK77_RS24290 c15c2e5c12cf18bf9f62e73c367f80a7 1144 PRINTS PR01806 Virulence factor MviN signature 385 404 1.3E-15 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ CAK77_RS24290 c15c2e5c12cf18bf9f62e73c367f80a7 1144 PRINTS PR01806 Virulence factor MviN signature 73 89 1.3E-15 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ CAK77_RS24290 c15c2e5c12cf18bf9f62e73c367f80a7 1144 PRINTS PR01806 Virulence factor MviN signature 54 73 1.3E-15 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ CAK77_RS03210 8efd86d91d36d821d9980f73d7e01c2b 174 SUPERFAMILY SSF50242 33 119 1.26E-5 T 06-07-2017 IPR008993 Tissue inhibitor of metalloproteinases-like, OB-fold CAK77_RS09990 78ed411d9471328aead17370ea8bf0fc 175 Pfam PF13452 N-terminal half of MaoC dehydratase 23 158 1.2E-32 T 06-07-2017 CAK77_RS09990 78ed411d9471328aead17370ea8bf0fc 175 Gene3D G3DSA:3.10.129.10 11 164 2.1E-9 T 06-07-2017 IPR029069 HotDog domain CAK77_RS09990 78ed411d9471328aead17370ea8bf0fc 175 SUPERFAMILY SSF54637 24 168 1.94E-11 T 06-07-2017 IPR029069 HotDog domain CAK77_RS20055 a72acf192d13d4ab3d249b0a5fe8339d 33 Pfam PF08213 Mitochondrial domain of unknown function (DUF1713) 1 33 4.5E-12 T 06-07-2017 IPR013177 Domain of unknown function DUF1713 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS20055 a72acf192d13d4ab3d249b0a5fe8339d 33 SMART SM01155 1 33 2.8E-8 T 06-07-2017 IPR013177 Domain of unknown function DUF1713 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAK77_RS03730 9fde89a13bce5b8057c921e704e07003 450 Gene3D G3DSA:3.40.50.1820 1 219 1.8E-35 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS03730 9fde89a13bce5b8057c921e704e07003 450 SUPERFAMILY SSF53474 2 136 3.97E-9 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS04060 c54fe099e02b3b2b85cba0614676f27e 338 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 45 281 2.2E-54 T 06-07-2017 IPR018713 Domain of unknown function DUF2236 CAK77_RS10850 23e666f2e803718439d241be658251cd 462 TIGRFAM TIGR03920 T7SS_EccD: type VII secretion integral membrane protein EccD 12 461 1.1E-87 T 06-07-2017 IPR006707 Type VII secretion system membrane protein EccD CAK77_RS10850 23e666f2e803718439d241be658251cd 462 PIRSF PIRSF017804 1 462 2.8E-93 T 06-07-2017 IPR006707 Type VII secretion system membrane protein EccD CAK77_RS10850 23e666f2e803718439d241be658251cd 462 Pfam PF08817 WXG100 protein secretion system (Wss), protein YukD 9 84 4.2E-23 T 06-07-2017 IPR024962 YukD-like CAK77_RS14860 7c7863b4aaa7b93033e9110c1f231e15 193 Pfam PF11452 Protein of unknown function (DUF3000) 6 185 1.3E-74 T 06-07-2017 IPR021555 Protein of unknown function DUF3000 CAK77_RS09055 590a92fefb9ab3e1b133c67fd9006d45 160 Pfam PF07681 DoxX 18 112 2.2E-6 T 06-07-2017 IPR032808 DoxX family CAK77_RS14170 494c9fb1f44b40664572010349f39fe4 220 Pfam PF01066 CDP-alcohol phosphatidyltransferase 27 91 7.9E-11 T 06-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CAK77_RS14170 494c9fb1f44b40664572010349f39fe4 220 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 69 91 - T 06-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CAK77_RS06035 2ecbf887b9adf1e751251fcbe908eeb5 139 Pfam PF14155 Domain of unknown function (DUF4307) 17 128 1.8E-36 T 06-07-2017 IPR025443 Protein of unknown function DUF4307 CAK77_RS02070 73239d68fb1622127dc79f0fc9954313 670 Pfam PF02384 N-6 DNA Methylase 325 557 3.5E-20 T 06-07-2017 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 CAK77_RS02070 73239d68fb1622127dc79f0fc9954313 670 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 372 386 1.2E-7 T 06-07-2017 CAK77_RS02070 73239d68fb1622127dc79f0fc9954313 670 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 465 477 1.2E-7 T 06-07-2017 CAK77_RS02070 73239d68fb1622127dc79f0fc9954313 670 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 481 505 1.2E-7 T 06-07-2017 CAK77_RS02070 73239d68fb1622127dc79f0fc9954313 670 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 348 364 1.2E-7 T 06-07-2017 CAK77_RS02070 73239d68fb1622127dc79f0fc9954313 670 SUPERFAMILY SSF53335 298 647 1.06E-57 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS02070 73239d68fb1622127dc79f0fc9954313 670 Gene3D G3DSA:3.40.50.150 351 574 4.3E-23 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS01445 ca597629b4acce923873bd0404422ec9 96 ProDom PD026347 LSR2-LIKE LSR2 ANTIGEN IMMUNE PRECURSOR RESPONSE SIGNAL PLASMID LYSYL GP61 4 96 9.0E-24 T 06-07-2017 IPR024412 Lsr2 CAK77_RS01445 ca597629b4acce923873bd0404422ec9 96 Pfam PF11774 Lsr2 5 96 7.6E-26 T 06-07-2017 IPR024412 Lsr2 CAK77_RS09030 eda9729417974a02b97892d6a62c80aa 417 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 13 255 5.0E-52 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAK77_RS09030 eda9729417974a02b97892d6a62c80aa 417 SMART SM00825 Beta-ketoacyl synthase 14 408 1.9E-12 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAK77_RS09030 eda9729417974a02b97892d6a62c80aa 417 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 264 374 1.4E-30 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAK77_RS09030 eda9729417974a02b97892d6a62c80aa 417 Gene3D G3DSA:3.40.47.10 272 417 3.3E-51 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS09030 eda9729417974a02b97892d6a62c80aa 417 SUPERFAMILY SSF53901 223 417 4.37E-62 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS09030 eda9729417974a02b97892d6a62c80aa 417 SUPERFAMILY SSF53901 13 260 2.03E-60 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS09030 eda9729417974a02b97892d6a62c80aa 417 Gene3D G3DSA:3.40.47.10 13 265 3.9E-58 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS23535 6c93dcd39d3548a23b69e797f163b7aa 221 Pfam PF11361 Protein of unknown function (DUF3159) 22 206 3.9E-58 T 06-07-2017 IPR016566 Uncharacterised conserved protein UCP010219 CAK77_RS23535 6c93dcd39d3548a23b69e797f163b7aa 221 PIRSF PIRSF010219 2 218 1.7E-58 T 06-07-2017 IPR016566 Uncharacterised conserved protein UCP010219 CAK77_RS18355 3169d083b74ef4dc03ca1d9a30b8dfa7 292 Gene3D G3DSA:3.40.50.1820 17 277 4.8E-40 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS18355 3169d083b74ef4dc03ca1d9a30b8dfa7 292 SUPERFAMILY SSF53474 16 277 1.1E-42 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS18355 3169d083b74ef4dc03ca1d9a30b8dfa7 292 Pfam PF12697 Alpha/beta hydrolase family 24 271 2.2E-19 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS09000 de6cdc79e247cb7c9f58a72927f082f7 177 Pfam PF11343 Protein of unknown function (DUF3145) 14 174 5.5E-69 T 06-07-2017 IPR021491 Protein of unknown function DUF3145 CAK77_RS23525 4aeedcc3336768a76358c648a8be2bf9 417 Pfam PF01699 Sodium/calcium exchanger protein 227 366 5.3E-9 T 06-07-2017 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 CAK77_RS23525 4aeedcc3336768a76358c648a8be2bf9 417 Pfam PF01699 Sodium/calcium exchanger protein 46 196 5.6E-10 T 06-07-2017 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 CAK77_RS01150 c225359df58dc6e9503a04b3a1997f03 154 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 36 82 1.2E-18 T 06-07-2017 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CAK77_RS01150 c225359df58dc6e9503a04b3a1997f03 154 Gene3D G3DSA:1.20.1290.10 8 149 1.5E-44 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAK77_RS01150 c225359df58dc6e9503a04b3a1997f03 154 SUPERFAMILY SSF69118 9 148 1.31E-36 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAK77_RS01150 c225359df58dc6e9503a04b3a1997f03 154 Pfam PF02627 Carboxymuconolactone decarboxylase family 17 99 8.2E-17 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CAK77_RS01020 c7f1c20cfd8a2239812a7e8ce7a66b02 650 Gene3D G3DSA:3.90.550.10 170 431 3.3E-11 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK77_RS01020 c7f1c20cfd8a2239812a7e8ce7a66b02 650 SUPERFAMILY SSF53448 344 452 1.13E-26 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK77_RS01020 c7f1c20cfd8a2239812a7e8ce7a66b02 650 SUPERFAMILY SSF53448 168 313 1.13E-26 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK77_RS01020 c7f1c20cfd8a2239812a7e8ce7a66b02 650 Pfam PF13641 Glycosyltransferase like family 2 169 429 7.1E-47 T 06-07-2017 CAK77_RS08935 f85c42454585d98ba2cebd7aaeec4de7 288 Gene3D G3DSA:3.40.50.300 3 226 5.8E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS08935 f85c42454585d98ba2cebd7aaeec4de7 288 SUPERFAMILY SSF52540 4 221 8.3E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS08935 f85c42454585d98ba2cebd7aaeec4de7 288 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK77_RS08935 f85c42454585d98ba2cebd7aaeec4de7 288 SMART SM00382 31 209 1.1E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS08935 f85c42454585d98ba2cebd7aaeec4de7 288 Pfam PF00005 ABC transporter 23 162 8.4E-24 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK77_RS18545 b8cc0284e19692d0aee2184a57ce50c2 275 Gene3D G3DSA:1.25.40.10 103 228 9.9E-6 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK77_RS24510 10b8b4e2b2480ab4faefd6a37868f114 68 Pfam PF00403 Heavy-metal-associated domain 6 64 2.9E-17 T 06-07-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CAK77_RS24510 10b8b4e2b2480ab4faefd6a37868f114 68 ProSitePatterns PS01047 Heavy-metal-associated domain. 8 37 - T 06-07-2017 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 CAK77_RS24510 10b8b4e2b2480ab4faefd6a37868f114 68 PRINTS PR00944 Copper ion binding protein signature 15 28 8.7E-6 T 06-07-2017 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 CAK77_RS24510 10b8b4e2b2480ab4faefd6a37868f114 68 PRINTS PR00944 Copper ion binding protein signature 28 41 8.7E-6 T 06-07-2017 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 CAK77_RS24510 10b8b4e2b2480ab4faefd6a37868f114 68 PRINTS PR00944 Copper ion binding protein signature 41 53 8.7E-6 T 06-07-2017 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 CAK77_RS24510 10b8b4e2b2480ab4faefd6a37868f114 68 PRINTS PR00944 Copper ion binding protein signature 53 66 8.7E-6 T 06-07-2017 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 CAK77_RS24510 10b8b4e2b2480ab4faefd6a37868f114 68 PRINTS PR00944 Copper ion binding protein signature 3 15 8.7E-6 T 06-07-2017 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 CAK77_RS24510 10b8b4e2b2480ab4faefd6a37868f114 68 SUPERFAMILY SSF55008 1 65 3.4E-19 T 06-07-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CAK77_RS24510 10b8b4e2b2480ab4faefd6a37868f114 68 Gene3D G3DSA:3.30.70.100 3 65 1.4E-22 T 06-07-2017 CAK77_RS04405 ed9c36f6af6b0d2cb430153a43073e41 371 Pfam PF06737 Transglycosylase-like domain 39 114 6.9E-34 T 06-07-2017 IPR010618 Transglycosylase-like CAK77_RS04405 ed9c36f6af6b0d2cb430153a43073e41 371 Gene3D G3DSA:1.10.530.10 18 118 8.0E-41 T 06-07-2017 CAK77_RS04405 ed9c36f6af6b0d2cb430153a43073e41 371 SUPERFAMILY SSF53955 39 116 1.83E-30 T 06-07-2017 IPR023346 Lysozyme-like domain CAK77_RS02340 3324a939137a046566b1b2da11447390 173 Pfam PF07332 Putative Actinobacterial Holin-X, holin superfamily III 39 151 1.5E-29 T 06-07-2017 IPR009937 Putative Actinobacterial Holin-X, holin superfamily III CAK77_RS17065 c1843149216a15cadab0a0ebbb4ee4ff 149 SUPERFAMILY SSF110921 61 147 1.44E-10 T 06-07-2017 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CAK77_RS20400 9698c7d9fc71e1559efd88082de6be9d 397 Pfam PF12770 CHAT domain 82 389 5.5E-11 T 06-07-2017 IPR024983 CHAT domain CAK77_RS13515 f4903f1acbe3c5c58fb725d6aebed9bc 313 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 25 303 4.6E-95 T 06-07-2017 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 CAK77_RS13515 f4903f1acbe3c5c58fb725d6aebed9bc 313 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 22 304 18.628 T 06-07-2017 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 CAK77_RS13515 f4903f1acbe3c5c58fb725d6aebed9bc 313 Pfam PF01040 UbiA prenyltransferase family 38 287 7.1E-62 T 06-07-2017 IPR000537 UbiA prenyltransferase family GO:0004659|GO:0016021 CAK77_RS07830 18e2dd4ae661528d62365cddf0d63d73 114 Pfam PF05305 Protein of unknown function (DUF732) 14 104 8.5E-9 T 06-07-2017 IPR007969 Domain of unknown function DUF732 CAK77_RS14585 656326aa239172db1f12e8129e973767 357 Pfam PF02625 XdhC and CoxI family 13 70 1.8E-19 T 06-07-2017 IPR003777 XdhC- CoxI CAK77_RS14585 656326aa239172db1f12e8129e973767 357 Pfam PF13478 XdhC Rossmann domain 189 336 1.5E-37 T 06-07-2017 IPR027051 XdhC Rossmann domain CAK77_RS11960 873adb30df5b7bad48fa21c1aa802eee 389 SUPERFAMILY SSF53850 42 273 5.66E-29 T 06-07-2017 CAK77_RS11960 873adb30df5b7bad48fa21c1aa802eee 389 Gene3D G3DSA:3.40.190.10 124 258 4.2E-9 T 06-07-2017 CAK77_RS11960 873adb30df5b7bad48fa21c1aa802eee 389 Pfam PF13379 NMT1-like family 40 274 9.8E-42 T 06-07-2017 CAK77_RS08790 e54aa0f5184421a8d80fc182eaff91b6 520 Pfam PF13777 Domain of unknown function (DUF4173) 279 467 1.9E-61 T 06-07-2017 IPR025231 Domain of unknown function DUF4173 CAK77_RS01310 9b8b2f97dff5bef05bab0e148fdb28b7 223 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 206 8.1E-23 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 CAK77_RS01310 9b8b2f97dff5bef05bab0e148fdb28b7 223 SMART SM00855 3 165 4.2E-7 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 CAK77_RS01310 9b8b2f97dff5bef05bab0e148fdb28b7 223 Gene3D G3DSA:3.40.50.1240 4 210 5.0E-25 T 06-07-2017 IPR029033 Histidine phosphatase superfamily CAK77_RS01310 9b8b2f97dff5bef05bab0e148fdb28b7 223 SUPERFAMILY SSF53254 1 210 1.17E-28 T 06-07-2017 IPR029033 Histidine phosphatase superfamily CAK77_RS13820 97f7d10a9e36dab1b9ade450ab0bd8a8 274 Hamap MF_01215 Orotidine 5'-phosphate decarboxylase [pyrF]. 5 271 32.483 T 06-07-2017 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686 CAK77_RS13820 97f7d10a9e36dab1b9ade450ab0bd8a8 274 SMART SM00934 19 261 2.6E-29 T 06-07-2017 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CAK77_RS13820 97f7d10a9e36dab1b9ade450ab0bd8a8 274 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 92 105 - T 06-07-2017 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CAK77_RS13820 97f7d10a9e36dab1b9ade450ab0bd8a8 274 Gene3D G3DSA:3.20.20.70 8 267 1.0E-55 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK77_RS13820 97f7d10a9e36dab1b9ade450ab0bd8a8 274 SUPERFAMILY SSF51366 6 267 2.54E-57 T 06-07-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CAK77_RS13820 97f7d10a9e36dab1b9ade450ab0bd8a8 274 TIGRFAM TIGR02127 pyrF_sub2: orotidine 5'-phosphate decarboxylase 6 260 3.7E-80 T 06-07-2017 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686 CAK77_RS13820 97f7d10a9e36dab1b9ade450ab0bd8a8 274 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 19 259 9.1E-38 T 06-07-2017 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CAK77_RS01430 35d3afb97aec11199434d6fe0f410e67 419 Pfam PF09594 Protein of unknown function (DUF2029) 73 307 4.5E-48 T 06-07-2017 IPR018584 Glycosyltransferase family 87 GO:0016758 CAK77_RS21805 83ed84f55c383a04098cdc117128c23c 373 Gene3D G3DSA:3.40.50.1820 37 372 1.3E-47 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS21805 83ed84f55c383a04098cdc117128c23c 373 SUPERFAMILY SSF53474 299 368 5.11E-19 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS21805 83ed84f55c383a04098cdc117128c23c 373 SUPERFAMILY SSF53474 55 158 5.11E-19 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS21805 83ed84f55c383a04098cdc117128c23c 373 SUPERFAMILY SSF53474 189 222 5.11E-19 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS18080 cbeb9bf70b91495eba54571c46bce852 236 Pfam PF01738 Dienelactone hydrolase family 13 225 2.4E-46 T 06-07-2017 IPR002925 Dienelactone hydrolase GO:0016787 CAK77_RS18080 cbeb9bf70b91495eba54571c46bce852 236 Gene3D G3DSA:3.40.50.1820 2 228 5.5E-44 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS18080 cbeb9bf70b91495eba54571c46bce852 236 SUPERFAMILY SSF53474 2 226 6.84E-34 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS22210 3a020ece66c1e472c8c224f4205b252e 118 Pfam PF03795 YCII-related domain 9 112 2.1E-18 T 06-07-2017 IPR005545 YCII-related CAK77_RS22210 3a020ece66c1e472c8c224f4205b252e 118 Gene3D G3DSA:3.30.70.1060 1 115 5.9E-43 T 06-07-2017 CAK77_RS22210 3a020ece66c1e472c8c224f4205b252e 118 SUPERFAMILY SSF54909 4 114 1.1E-30 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAK77_RS08695 47c8e41d4e5343365f2c4c16619fdaea 671 Pfam PF04536 Acid phosphatase of thylakoid lumen protein 40 155 1.8E-18 T 06-07-2017 IPR007621 TPM domain CAK77_RS20575 ed076b61d61f462a602d7e14fe6343ae 262 Pfam PF05711 Macrocin-O-methyltransferase (TylF) 82 227 7.4E-15 T 06-07-2017 IPR008884 Macrocin-O-methyltransferase CAK77_RS20575 ed076b61d61f462a602d7e14fe6343ae 262 Gene3D G3DSA:3.40.50.150 157 258 1.6E-4 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS21590 e3e06dd55662705b943339c61b5575d3 606 Pfam PF00012 Hsp70 protein 156 337 7.3E-16 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CAK77_RS21590 e3e06dd55662705b943339c61b5575d3 606 SUPERFAMILY SSF53067 158 338 1.23E-29 T 06-07-2017 CAK77_RS21590 e3e06dd55662705b943339c61b5575d3 606 PRINTS PR01217 Proline rich extensin signature 486 507 1.9E-9 T 06-07-2017 CAK77_RS21590 e3e06dd55662705b943339c61b5575d3 606 PRINTS PR01217 Proline rich extensin signature 508 524 1.9E-9 T 06-07-2017 CAK77_RS21590 e3e06dd55662705b943339c61b5575d3 606 PRINTS PR01217 Proline rich extensin signature 549 574 1.9E-9 T 06-07-2017 CAK77_RS21590 e3e06dd55662705b943339c61b5575d3 606 PRINTS PR01217 Proline rich extensin signature 526 543 1.9E-9 T 06-07-2017 CAK77_RS21590 e3e06dd55662705b943339c61b5575d3 606 Gene3D G3DSA:3.30.420.40 277 314 1.3E-5 T 06-07-2017 CAK77_RS21590 e3e06dd55662705b943339c61b5575d3 606 Gene3D G3DSA:3.30.420.40 159 195 1.3E-5 T 06-07-2017 CAK77_RS21590 e3e06dd55662705b943339c61b5575d3 606 Gene3D G3DSA:3.90.640.10 196 264 1.1E-5 T 06-07-2017 CAK77_RS22890 d03a8f0f68a1988db43366a5dc416be4 510 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 183 374 3.6E-14 T 06-07-2017 IPR024516 Mammalian cell entry, C-terminal CAK77_RS22890 d03a8f0f68a1988db43366a5dc416be4 510 Pfam PF02470 MlaD protein 50 128 6.7E-8 T 06-07-2017 IPR003399 Mce/MlaD CAK77_RS21835 044f257d8a4cfe119b44a889b187547c 415 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 7 134 4.0E-11 T 06-07-2017 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 CAK77_RS21835 044f257d8a4cfe119b44a889b187547c 415 SUPERFAMILY SSF51735 7 172 1.01E-14 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS21835 044f257d8a4cfe119b44a889b187547c 415 Gene3D G3DSA:3.40.50.720 7 157 2.5E-16 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS24030 3d411a84b5b8f5973baf815a68cb2e9d 411 Pfam PF13556 PucR C-terminal helix-turn-helix domain 344 397 5.8E-10 T 06-07-2017 IPR025736 PucR C-terminal helix-turn-helix domain CAK77_RS24030 3d411a84b5b8f5973baf815a68cb2e9d 411 Gene3D G3DSA:1.10.10.60 348 375 7.1E-4 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS08010 9e22b7ca67182ac93eb6ea27fbe8b6e8 1323 Pfam PF10145 Phage-related minor tail protein 247 448 1.3E-42 T 06-07-2017 IPR010090 Phage tail tape measure protein CAK77_RS08010 9e22b7ca67182ac93eb6ea27fbe8b6e8 1323 TIGRFAM TIGR01760 tape_meas_TP901: phage tail tape measure protein, TP901 family, core region 210 551 8.4E-52 T 06-07-2017 IPR010090 Phage tail tape measure protein CAK77_RS14645 aec9b388934d4a3d8d80ffe9585c1ca1 505 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 42 469 7.0E-82 T 06-07-2017 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 CAK77_RS08670 75c769b2db698e22b21231628ea87d3b 298 Pfam PF10118 Predicted metal-dependent hydrolase 19 274 4.7E-72 T 06-07-2017 IPR016516 Uncharacterised conserved protein UCP07580 CAK77_RS08670 75c769b2db698e22b21231628ea87d3b 298 PIRSF PIRSF007580 3 290 3.2E-66 T 06-07-2017 IPR016516 Uncharacterised conserved protein UCP07580 CAK77_RS03330 5b885d7c65ab31e1f76a60421f33b847 195 Pfam PF09203 MspA 24 191 3.7E-48 T 06-07-2017 IPR015286 Porin family, mycobacterial-type CAK77_RS03330 5b885d7c65ab31e1f76a60421f33b847 195 Gene3D G3DSA:2.60.40.1650 133 195 3.3E-29 T 06-07-2017 CAK77_RS03330 5b885d7c65ab31e1f76a60421f33b847 195 Gene3D G3DSA:2.60.40.1650 18 84 3.3E-29 T 06-07-2017 CAK77_RS03330 5b885d7c65ab31e1f76a60421f33b847 195 SUPERFAMILY SSF56959 19 194 3.2E-13 T 06-07-2017 IPR016183 Leukocidin/porin GO:0005576|GO:0051715 CAK77_RS07060 a832852597dd85ce1300b358a8695e87 139 SUPERFAMILY SSF54197 1 133 8.97E-40 T 06-07-2017 IPR011146 HIT-like domain GO:0003824 CAK77_RS07060 a832852597dd85ce1300b358a8695e87 139 PRINTS PR00332 Histidine triad family signature 93 103 2.2E-15 T 06-07-2017 IPR001310 Histidine triad (HIT) protein CAK77_RS07060 a832852597dd85ce1300b358a8695e87 139 PRINTS PR00332 Histidine triad family signature 25 43 2.2E-15 T 06-07-2017 IPR001310 Histidine triad (HIT) protein CAK77_RS07060 a832852597dd85ce1300b358a8695e87 139 PRINTS PR00332 Histidine triad family signature 4 20 2.2E-15 T 06-07-2017 IPR001310 Histidine triad (HIT) protein CAK77_RS07060 a832852597dd85ce1300b358a8695e87 139 Gene3D G3DSA:3.30.428.10 2 121 2.0E-41 T 06-07-2017 IPR011146 HIT-like domain GO:0003824 CAK77_RS07060 a832852597dd85ce1300b358a8695e87 139 Pfam PF01230 HIT domain 11 106 1.8E-25 T 06-07-2017 IPR001310 Histidine triad (HIT) protein CAK77_RS09695 b72d6e65580bd4a590a4a74f9d0f06b9 226 Pfam PF11353 Protein of unknown function (DUF3153) 13 177 1.8E-8 T 06-07-2017 IPR021499 Protein of unknown function DUF3153 CAK77_RS09480 ac36956e86e616e420c6fe899977d4c5 252 Pfam PF02654 Cobalamin-5-phosphate synthase 14 246 1.2E-45 T 06-07-2017 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CAK77_RS09480 ac36956e86e616e420c6fe899977d4c5 252 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 252 39.365 T 06-07-2017 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CAK77_RS21285 d676ed0e9dfdfa49f345cc4bb1050753 555 TIGRFAM TIGR00831 a_cpa1: Na+/H+ antiporter 33 549 9.1E-98 T 06-07-2017 IPR004705 Cation/H+ exchanger, CPA1 family, bacteria GO:0006812|GO:0015299|GO:0016021 CAK77_RS21285 d676ed0e9dfdfa49f345cc4bb1050753 555 Pfam PF00999 Sodium/hydrogen exchanger family 36 422 3.3E-50 T 06-07-2017 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CAK77_RS17080 3c5bb1804d0926e2339bd716f42be057 220 Pfam PF13460 NAD(P)H-binding 9 196 1.5E-41 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS17080 3c5bb1804d0926e2339bd716f42be057 220 SUPERFAMILY SSF51735 2 209 2.01E-34 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS17080 3c5bb1804d0926e2339bd716f42be057 220 Gene3D G3DSA:3.40.50.720 2 210 3.0E-39 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS23255 b7f6b36dbe391eb2f392835685cb705f 368 Pfam PF12704 MacB-like periplasmic core domain 16 217 4.3E-18 T 06-07-2017 IPR025857 MacB-like periplasmic core domain CAK77_RS23255 b7f6b36dbe391eb2f392835685cb705f 368 Pfam PF02687 FtsX-like permease family 249 362 4.7E-15 T 06-07-2017 IPR003838 ABC transporter permease protein domain GO:0016020 CAK77_RS22345 a7d9c1a8db4612e3b48279c751616373 319 Pfam PF09678 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) 43 283 7.4E-64 T 06-07-2017 IPR019108 Cytochrome c oxidase caa3-type, assembly factor CtaG-related CAK77_RS23020 01c58c5eebbedea6c4b4243cb059ce12 200 SUPERFAMILY SSF46689 3 73 1.95E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS23020 01c58c5eebbedea6c4b4243cb059ce12 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 57 1.4E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS23020 01c58c5eebbedea6c4b4243cb059ce12 200 Gene3D G3DSA:1.10.357.10 10 191 1.0E-20 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS08570 ac199bf404bbd09b969645f5f1f43b7b 398 SUPERFAMILY SSF55729 163 299 2.74E-21 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS08570 ac199bf404bbd09b969645f5f1f43b7b 398 SUPERFAMILY SSF55729 326 378 2.74E-21 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS08570 ac199bf404bbd09b969645f5f1f43b7b 398 SUPERFAMILY SSF55729 30 135 2.74E-21 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS08570 ac199bf404bbd09b969645f5f1f43b7b 398 Gene3D G3DSA:3.40.630.30 211 373 6.4E-5 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS08570 ac199bf404bbd09b969645f5f1f43b7b 398 Gene3D G3DSA:3.40.630.30 27 143 9.9E-4 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS18045 ff56d25186c42c8d3022ece04ab83f5f 560 ProSitePatterns PS00455 Putative AMP-binding domain signature. 168 179 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAK77_RS18045 ff56d25186c42c8d3022ece04ab83f5f 560 Pfam PF00501 AMP-binding enzyme 34 422 2.1E-57 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAK77_RS18045 ff56d25186c42c8d3022ece04ab83f5f 560 SUPERFAMILY SSF56801 28 520 3.14E-94 T 06-07-2017 CAK77_RS18045 ff56d25186c42c8d3022ece04ab83f5f 560 Gene3D G3DSA:3.40.50.980 173 331 1.3E-22 T 06-07-2017 CAK77_RS18045 ff56d25186c42c8d3022ece04ab83f5f 560 Gene3D G3DSA:2.30.38.10 344 415 7.3E-16 T 06-07-2017 CAK77_RS18045 ff56d25186c42c8d3022ece04ab83f5f 560 Pfam PF13193 AMP-binding enzyme C-terminal domain 432 508 1.3E-5 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAK77_RS18045 ff56d25186c42c8d3022ece04ab83f5f 560 Gene3D G3DSA:3.30.300.30 418 517 1.1E-15 T 06-07-2017 CAK77_RS18045 ff56d25186c42c8d3022ece04ab83f5f 560 Gene3D G3DSA:3.40.50.980 33 172 1.4E-17 T 06-07-2017 CAK77_RS15270 ff4023466c0e4d36488f1bd5bc45c8d9 269 Pfam PF04012 PspA/IM30 family 3 241 1.8E-55 T 06-07-2017 IPR007157 PspA/IM30 CAK77_RS14000 5267726fe9c494385fb11c4e8c91691b 238 Pfam PF09323 Domain of unknown function (DUF1980) 9 103 2.3E-9 T 06-07-2017 IPR015402 Protein of unknown function DUF1980 CAK77_RS14000 5267726fe9c494385fb11c4e8c91691b 238 TIGRFAM TIGR03943 TIGR03943: TIGR03943 family protein 23 238 2.2E-52 T 06-07-2017 IPR015402 Protein of unknown function DUF1980 CAK77_RS01640 3f5ed17e8219d556425e1618a5132b4b 422 Gene3D G3DSA:3.40.1190.10 47 283 1.1E-41 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAK77_RS01640 3f5ed17e8219d556425e1618a5132b4b 422 Pfam PF08353 Domain of unknown function (DUF1727) 303 409 2.6E-24 T 06-07-2017 IPR013564 Domain of unknown function DUF1727 CAK77_RS01640 3f5ed17e8219d556425e1618a5132b4b 422 SUPERFAMILY SSF53623 220 280 2.35E-33 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAK77_RS01640 3f5ed17e8219d556425e1618a5132b4b 422 SUPERFAMILY SSF53623 47 193 2.35E-33 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAK77_RS01640 3f5ed17e8219d556425e1618a5132b4b 422 Pfam PF08245 Mur ligase middle domain 60 265 8.1E-17 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAK77_RS19910 80b4fd64860825e0edc3dc154d138dd9 535 Pfam PF05140 ResB-like family 21 507 3.3E-133 T 06-07-2017 IPR007816 ResB-like domain CAK77_RS04230 94706a22397d61a9d17baf876444581a 270 Gene3D G3DSA:3.90.226.10 5 269 1.4E-76 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS04230 94706a22397d61a9d17baf876444581a 270 SUPERFAMILY SSF52096 6 269 2.33E-75 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS04230 94706a22397d61a9d17baf876444581a 270 Pfam PF00378 Enoyl-CoA hydratase/isomerase 8 269 4.7E-57 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAK77_RS04230 94706a22397d61a9d17baf876444581a 270 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 115 135 - T 06-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CAK77_RS13455 20a4e133b845cea32982b582e87360c0 414 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 11 414 5.8E-173 T 06-07-2017 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 CAK77_RS13455 20a4e133b845cea32982b582e87360c0 414 Gene3D G3DSA:3.90.1150.10 290 407 1.0E-26 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAK77_RS13455 20a4e133b845cea32982b582e87360c0 414 SUPERFAMILY SSF53383 8 409 7.56E-118 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAK77_RS13455 20a4e133b845cea32982b582e87360c0 414 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 223 242 - T 06-07-2017 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site CAK77_RS13455 20a4e133b845cea32982b582e87360c0 414 Pfam PF00266 Aminotransferase class-V 31 402 3.9E-136 T 06-07-2017 IPR000192 Aminotransferase class V domain CAK77_RS13455 20a4e133b845cea32982b582e87360c0 414 Gene3D G3DSA:3.40.640.10 42 289 1.2E-84 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAK77_RS14940 5a7275e68d52d9fdd8c7224d2b10e78e 148 Pfam PF04075 Domain of unknown function (DUF385) 29 97 1.0E-5 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CAK77_RS22315 dad0ddcec8d7a9f075a18dc5d91f9f0e 259 Gene3D G3DSA:3.40.50.150 57 167 7.7E-26 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS22315 dad0ddcec8d7a9f075a18dc5d91f9f0e 259 Pfam PF08241 Methyltransferase domain 64 159 3.0E-17 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CAK77_RS22315 dad0ddcec8d7a9f075a18dc5d91f9f0e 259 SUPERFAMILY SSF53335 48 218 2.61E-27 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS17125 41e61bd71dfb1caac63451c709465a22 109 Pfam PF03793 PASTA domain 46 107 6.7E-13 T 06-07-2017 IPR005543 PASTA domain CAK77_RS17125 41e61bd71dfb1caac63451c709465a22 109 SMART SM00740 41 109 4.4E-8 T 06-07-2017 IPR005543 PASTA domain CAK77_RS04470 d5c2c85f7f5ad1062693c95b23a89d07 270 Gene3D G3DSA:3.30.1330.30 7 105 3.9E-10 T 06-07-2017 IPR029064 50S ribosomal protein L30e-like CAK77_RS04470 d5c2c85f7f5ad1062693c95b23a89d07 270 Pfam PF00588 SpoU rRNA Methylase family 120 263 1.2E-30 T 06-07-2017 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CAK77_RS04470 d5c2c85f7f5ad1062693c95b23a89d07 270 SUPERFAMILY SSF75217 97 267 3.79E-37 T 06-07-2017 IPR029028 Alpha/beta knot methyltransferases CAK77_RS04470 d5c2c85f7f5ad1062693c95b23a89d07 270 Gene3D G3DSA:3.40.1280.10 115 267 8.5E-45 T 06-07-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CAK77_RS04470 d5c2c85f7f5ad1062693c95b23a89d07 270 SUPERFAMILY SSF55315 6 106 1.39E-11 T 06-07-2017 IPR029064 50S ribosomal protein L30e-like CAK77_RS17090 4be4480323b5e91d7afec84c3d024a73 467 Pfam PF03929 PepSY-associated TM region 27 397 5.7E-53 T 06-07-2017 IPR005625 PepSY-associated TM protein CAK77_RS23415 7e50c6ac55595bd18f1adb17e822b5ec 112 TIGRFAM TIGR04529 MTB_hemophore: hemophore-related protein, Rv0203/Rv1174c family 41 112 2.8E-16 T 06-07-2017 IPR032407 Haemophore, haem-binding GO:0020037 CAK77_RS11965 d3cd95920bb8e1f53e983ce14d44ea5a 274 Gene3D G3DSA:1.10.3720.10 71 263 1.3E-20 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS11965 d3cd95920bb8e1f53e983ce14d44ea5a 274 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 98 269 4.2E-19 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS11965 d3cd95920bb8e1f53e983ce14d44ea5a 274 SUPERFAMILY SSF161098 74 261 2.09E-29 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS13935 821b50841249a6fc409c2bb91377ba60 428 Pfam PF02618 YceG-like family 98 416 8.7E-57 T 06-07-2017 IPR003770 Uncharacterised protein family UPF0755, YceG-like CAK77_RS13935 821b50841249a6fc409c2bb91377ba60 428 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 62 414 2.2E-33 T 06-07-2017 IPR003770 Uncharacterised protein family UPF0755, YceG-like CAK77_RS18530 b72d7f66ddb96b4046daab8222a9323e 134 ProDom PD032647 MB3446 ML0386 RV3412/MT3521 CGL0602 25 120 1.0E-47 T 06-07-2017 CAK77_RS02825 9b1612b5ba5c88ddce9710bad9a74e0e 271 SUPERFAMILY SSF53067 2 124 2.49E-25 T 06-07-2017 CAK77_RS02825 9b1612b5ba5c88ddce9710bad9a74e0e 271 Hamap MF_01274 Type III pantothenate kinase [coaX]. 1 260 32.02 T 06-07-2017 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CAK77_RS02825 9b1612b5ba5c88ddce9710bad9a74e0e 271 SUPERFAMILY SSF53067 126 259 1.81E-30 T 06-07-2017 CAK77_RS02825 9b1612b5ba5c88ddce9710bad9a74e0e 271 Pfam PF03309 Type III pantothenate kinase 2 208 3.9E-58 T 06-07-2017 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CAK77_RS02825 9b1612b5ba5c88ddce9710bad9a74e0e 271 TIGRFAM TIGR00671 baf: pantothenate kinase, type III 2 256 1.0E-88 T 06-07-2017 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CAK77_RS02825 9b1612b5ba5c88ddce9710bad9a74e0e 271 Gene3D G3DSA:3.30.420.40 97 264 6.1E-49 T 06-07-2017 CAK77_RS06255 113861902a19426eb29769a2b331c60b 155 Pfam PF03780 Asp23 family, cell envelope-related function 29 138 3.1E-30 T 06-07-2017 IPR005531 Alkaline shock protein Asp23 CAK77_RS02725 9fb4e212f8985d625ba043fa2789edf3 193 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 20 186 2.1E-64 T 06-07-2017 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620 CAK77_RS02725 9fb4e212f8985d625ba043fa2789edf3 193 Pfam PF00156 Phosphoribosyl transferase domain 36 173 1.9E-18 T 06-07-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 CAK77_RS02725 9fb4e212f8985d625ba043fa2789edf3 193 SUPERFAMILY SSF53271 13 191 1.84E-50 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like CAK77_RS02725 9fb4e212f8985d625ba043fa2789edf3 193 Gene3D G3DSA:3.40.50.2020 9 192 3.7E-77 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like CAK77_RS14800 6b291e76a696cf5858da57ba6cb10f71 260 Pfam PF01872 RibD C-terminal domain 45 234 1.3E-36 T 06-07-2017 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CAK77_RS14800 6b291e76a696cf5858da57ba6cb10f71 260 Gene3D G3DSA:3.40.430.10 39 258 1.8E-57 T 06-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CAK77_RS14800 6b291e76a696cf5858da57ba6cb10f71 260 SUPERFAMILY SSF53597 45 259 3.93E-38 T 06-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CAK77_RS00700 b8e7f26f88a7f67435727f41903bbcbb 162 Gene3D G3DSA:3.50.30.40 10 162 1.1E-44 T 06-07-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CAK77_RS00700 b8e7f26f88a7f67435727f41903bbcbb 162 TIGRFAM TIGR01935 NOT-MenG: RraA family 11 159 2.0E-55 T 06-07-2017 IPR010203 Regulator of ribonuclease activity A GO:0008428|GO:0051252 CAK77_RS00700 b8e7f26f88a7f67435727f41903bbcbb 162 Pfam PF03737 Demethylmenaquinone methyltransferase 11 159 1.9E-39 T 06-07-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CAK77_RS00700 b8e7f26f88a7f67435727f41903bbcbb 162 SUPERFAMILY SSF89562 10 161 2.62E-42 T 06-07-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CAK77_RS01345 3f5dfca8c3bcfe8a74c9452ce4679c60 368 Pfam PF00005 ABC transporter 19 163 4.0E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAK77_RS01345 3f5dfca8c3bcfe8a74c9452ce4679c60 368 SMART SM00382 27 213 2.4E-16 T 06-07-2017 IPR003593 AAA+ ATPase domain CAK77_RS01345 3f5dfca8c3bcfe8a74c9452ce4679c60 368 Gene3D G3DSA:3.40.50.300 1 237 1.1E-71 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS01345 3f5dfca8c3bcfe8a74c9452ce4679c60 368 SUPERFAMILY SSF52540 1 239 1.82E-70 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS01345 3f5dfca8c3bcfe8a74c9452ce4679c60 368 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAK77_RS22305 002ebd96554ea658d65be61db9feafc7 210 Gene3D G3DSA:1.10.357.10 12 196 1.6E-21 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS22305 002ebd96554ea658d65be61db9feafc7 210 SUPERFAMILY SSF46689 11 91 2.82E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS22305 002ebd96554ea658d65be61db9feafc7 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 70 2.7E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS05560 064eb9570dbc076160342b442462e1bc 514 Pfam PF02366 Dolichyl-phosphate-mannose-protein mannosyltransferase 116 291 1.8E-9 T 06-07-2017 IPR003342 Glycosyl transferase family 39/83 GO:0000030|GO:0006493|GO:0016020 Reactome: R-HSA-5173105 CAK77_RS05560 064eb9570dbc076160342b442462e1bc 514 Pfam PF16192 C-terminal four TMM region of protein-O-mannosyltransferase 321 513 1.3E-19 T 06-07-2017 IPR032421 Protein O-mannosyl-transferase, C-terminal four TM domain KEGG: 00500+2.4.1.10|KEGG: 00514+2.4.1.109|MetaCyc: PWY-822|Reactome: R-HSA-5173105 CAK77_RS22375 a0090e1704755d07ad537ace67734524 130 Pfam PF02467 Transcription factor WhiB 46 115 1.7E-18 T 06-07-2017 IPR003482 Transcription factor WhiB CAK77_RS22375 a0090e1704755d07ad537ace67734524 130 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 20 118 16.019 T 06-07-2017 IPR003482 Transcription factor WhiB CAK77_RS05470 25ac11f448c7c992ba7c3744747ddb65 217 Pfam PF13302 Acetyltransferase (GNAT) domain 51 172 5.9E-13 T 06-07-2017 IPR000182 GNAT domain GO:0008080 CAK77_RS05470 25ac11f448c7c992ba7c3744747ddb65 217 Gene3D G3DSA:3.40.630.30 11 202 1.8E-45 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS05470 25ac11f448c7c992ba7c3744747ddb65 217 SUPERFAMILY SSF55729 28 195 8.13E-34 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS03290 15b5f0dbd3a888c30b976a2b1aeb8eb3 949 Pfam PF13244 Domain of unknown function (DUF4040) 602 666 2.4E-19 T 06-07-2017 IPR025383 Domain of unknown function DUF4040 CAK77_RS03290 15b5f0dbd3a888c30b976a2b1aeb8eb3 949 Pfam PF00361 Proton-conducting membrane transporter 127 419 3.6E-58 T 06-07-2017 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS03290 15b5f0dbd3a888c30b976a2b1aeb8eb3 949 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 799 921 1.0E-28 T 06-07-2017 IPR007182 Na+/H+ antiporter MnhB subunit-related protein CAK77_RS03290 15b5f0dbd3a888c30b976a2b1aeb8eb3 949 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 413 432 4.6E-34 T 06-07-2017 CAK77_RS03290 15b5f0dbd3a888c30b976a2b1aeb8eb3 949 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 104 124 4.6E-34 T 06-07-2017 CAK77_RS03290 15b5f0dbd3a888c30b976a2b1aeb8eb3 949 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 151 172 4.6E-34 T 06-07-2017 CAK77_RS03290 15b5f0dbd3a888c30b976a2b1aeb8eb3 949 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 236 262 4.6E-34 T 06-07-2017 CAK77_RS03290 15b5f0dbd3a888c30b976a2b1aeb8eb3 949 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 304 316 4.6E-34 T 06-07-2017 CAK77_RS03290 15b5f0dbd3a888c30b976a2b1aeb8eb3 949 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 71 96 4.6E-34 T 06-07-2017 CAK77_RS03290 15b5f0dbd3a888c30b976a2b1aeb8eb3 949 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 214 235 4.6E-34 T 06-07-2017 CAK77_RS03290 15b5f0dbd3a888c30b976a2b1aeb8eb3 949 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 59 100 5.2E-7 T 06-07-2017 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS20760 31174bc3994413ef250c6e1e8142b3fd 315 Pfam PF14240 YHYH protein 178 249 1.5E-10 T 06-07-2017 IPR025924 YHYH domain CAK77_RS06315 95b5a184acd339a50c048ec6d1fbba6f 59 Pfam PF04328 Protein of unknown function (DUF466) 2 59 1.3E-22 T 06-07-2017 IPR007423 Protein of unknown function DUF466 CAK77_RS00965 ffb59ebbbca26e0b0e6e6f3652d02cce 136 SUPERFAMILY SSF55331 2 128 2.96E-31 T 06-07-2017 IPR014347 Tautomerase/MIF superfamily CAK77_RS00965 ffb59ebbbca26e0b0e6e6f3652d02cce 136 Pfam PF14552 Tautomerase enzyme 38 118 1.4E-26 T 06-07-2017 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 CAK77_RS00965 ffb59ebbbca26e0b0e6e6f3652d02cce 136 Gene3D G3DSA:3.30.429.10 3 125 2.6E-31 T 06-07-2017 CAK77_RS01825 4093ab167828524c8cbeec002e296036 292 Gene3D G3DSA:3.20.20.140 7 291 4.0E-99 T 06-07-2017 CAK77_RS01825 4093ab167828524c8cbeec002e296036 292 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 5 291 2.8E-70 T 06-07-2017 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 CAK77_RS01825 4093ab167828524c8cbeec002e296036 292 Pfam PF01979 Amidohydrolase family 7 224 6.0E-12 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAK77_RS01825 4093ab167828524c8cbeec002e296036 292 SUPERFAMILY SSF51556 7 291 5.05E-87 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK77_RS02590 8bf7ae6fd355f0c5600c448445c99a86 140 Gene3D G3DSA:1.10.260.40 24 105 5.2E-7 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK77_RS15060 319659b87ee1a9ea20a1fa32a5753276 323 PIRSF PIRSF035875 2 305 2.6E-56 T 06-07-2017 IPR017039 Virulence factor BrkB CAK77_RS15060 319659b87ee1a9ea20a1fa32a5753276 323 Pfam PF03631 Virulence factor BrkB 27 284 3.3E-42 T 06-07-2017 IPR017039 Virulence factor BrkB CAK77_RS06405 c8ef22cc40939d0d30c966398d9fafc8 514 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 68 232 9.2E-11 T 06-07-2017 CAK77_RS06850 c371e12446992b2250a8147f6e8d42a6 316 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 32 262 1.1E-36 T 06-07-2017 IPR018713 Domain of unknown function DUF2236 CAK77_RS11100 8fd6e4b98c8c6d8cb7d0d6479158ff2c 472 Gene3D G3DSA:3.50.50.60 359 410 1.7E-43 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS11100 8fd6e4b98c8c6d8cb7d0d6479158ff2c 472 Gene3D G3DSA:3.50.50.60 178 258 1.7E-43 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS11100 8fd6e4b98c8c6d8cb7d0d6479158ff2c 472 Gene3D G3DSA:3.50.50.60 28 126 1.7E-43 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS11100 8fd6e4b98c8c6d8cb7d0d6479158ff2c 472 SUPERFAMILY SSF51905 359 413 3.43E-41 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS11100 8fd6e4b98c8c6d8cb7d0d6479158ff2c 472 SUPERFAMILY SSF51905 34 259 3.43E-41 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS11100 8fd6e4b98c8c6d8cb7d0d6479158ff2c 472 Pfam PF01266 FAD dependent oxidoreductase 35 395 4.1E-53 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CAK77_RS11985 08bbfba671a61d2aff97253ae0aa09ae 525 SUPERFAMILY SSF81342 11 287 2.2E-62 T 06-07-2017 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 CAK77_RS11985 08bbfba671a61d2aff97253ae0aa09ae 525 Pfam PF13631 Cytochrome b(N-terminal)/b6/petB 110 283 2.2E-62 T 06-07-2017 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 CAK77_RS11985 08bbfba671a61d2aff97253ae0aa09ae 525 Gene3D G3DSA:1.20.810.10 11 429 2.5E-84 T 06-07-2017 IPR027387 Cytochrome b/b6-like domain Reactome: R-HSA-611105 CAK77_RS09270 f253c5a900ab927ba1b66e5b12785d5a 474 SMART SM00955 45 365 1.9E-54 T 06-07-2017 CAK77_RS09270 f253c5a900ab927ba1b66e5b12785d5a 474 Pfam PF00773 RNB domain 45 356 1.6E-37 T 06-07-2017 CAK77_RS09270 f253c5a900ab927ba1b66e5b12785d5a 474 SUPERFAMILY SSF50249 11 407 9.14E-84 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAK77_RS18250 581de2bd4f44da285d47d76f3033d86e 450 Gene3D G3DSA:3.90.1720.10 334 448 7.6E-33 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain CAK77_RS18250 581de2bd4f44da285d47d76f3033d86e 450 Pfam PF00877 NlpC/P60 family 351 438 3.4E-17 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain CAK77_RS18250 581de2bd4f44da285d47d76f3033d86e 450 SUPERFAMILY SSF54001 334 448 1.57E-29 T 06-07-2017 CAK77_RS17005 0775674c526ce0b80735c7da54a8e674 145 Pfam PF10947 Protein of unknown function (DUF2628) 15 100 1.5E-12 T 06-07-2017 IPR024399 Protein of unknown function DUF2628 CAK77_RS17005 0775674c526ce0b80735c7da54a8e674 145 ProDom PD031864 YIGF SIMILAR ESCHERICHIA COLI MEMBRANE XCC4223 XAC4357 XAC2195 10 123 6.0E-11 T 06-07-2017 CAK77_RS06550 330cc5538c664e96cbc0dff7b99504ed 94 Hamap MF_00434 Putative pterin-4-alpha-carbinolamine dehydratase. 1 92 19.704 T 06-07-2017 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 CAK77_RS06550 330cc5538c664e96cbc0dff7b99504ed 94 SUPERFAMILY SSF55248 2 92 3.4E-27 T 06-07-2017 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 CAK77_RS06550 330cc5538c664e96cbc0dff7b99504ed 94 Pfam PF01329 Pterin 4 alpha carbinolamine dehydratase 4 90 1.9E-24 T 06-07-2017 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 CAK77_RS06550 330cc5538c664e96cbc0dff7b99504ed 94 Gene3D G3DSA:3.30.1360.20 2 92 4.3E-25 T 06-07-2017 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 CAK77_RS09320 b84626dbe1b2fefbbc58d355b503da7e 122 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 116 1.6E-5 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CAK77_RS09320 b84626dbe1b2fefbbc58d355b503da7e 122 SUPERFAMILY SSF54593 1 120 5.5E-21 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK77_RS09320 b84626dbe1b2fefbbc58d355b503da7e 122 Gene3D G3DSA:3.10.180.10 1 119 4.4E-18 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK77_RS01040 6f1f06725d6a84c2eb4448fc9abc99a6 324 Pfam PF00756 Putative esterase 52 317 1.3E-56 T 06-07-2017 IPR000801 Putative esterase Reactome: R-HSA-156590 CAK77_RS01040 6f1f06725d6a84c2eb4448fc9abc99a6 324 Gene3D G3DSA:3.40.50.1820 42 323 4.0E-105 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS01040 6f1f06725d6a84c2eb4448fc9abc99a6 324 SUPERFAMILY SSF53474 39 321 8.49E-33 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS22520 126bb29eb82bad63b3fb44ca0e527b67 401 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 53 355 6.4E-37 T 06-07-2017 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD CAK77_RS24190 4ec07d05e635b5f85f3ea5d7a2da83af 364 Pfam PF00676 Dehydrogenase E1 component 40 306 5.5E-81 T 06-07-2017 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 CAK77_RS24190 4ec07d05e635b5f85f3ea5d7a2da83af 364 SUPERFAMILY SSF52518 33 346 1.84E-94 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK77_RS24190 4ec07d05e635b5f85f3ea5d7a2da83af 364 TIGRFAM TIGR03181 PDH_E1_alph_x: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 3 347 1.6E-132 T 06-07-2017 IPR017596 Pyruvate dehydrogenase E1 component subunit alpha/BCKADH E1-alpha KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 CAK77_RS24190 4ec07d05e635b5f85f3ea5d7a2da83af 364 Gene3D G3DSA:3.40.50.970 2 347 6.3E-125 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAK77_RS17230 cec814a7894c375de4b6a3b18004e529 171 Pfam PF09348 Domain of unknown function (DUF1990) 8 167 1.0E-44 T 06-07-2017 IPR018960 Domain of unknown function DUF1990 CAK77_RS17230 cec814a7894c375de4b6a3b18004e529 171 PIRSF PIRSF010260 1 171 5.8E-55 T 06-07-2017 IPR014457 Uncharacterised conserved protein UCP010260 CAK77_RS21320 525c6625ff608ad620516491b6269628 419 Gene3D G3DSA:3.50.50.60 364 402 1.3E-15 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS21320 525c6625ff608ad620516491b6269628 419 Gene3D G3DSA:3.50.50.60 203 287 1.3E-15 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS21320 525c6625ff608ad620516491b6269628 419 Gene3D G3DSA:3.50.50.60 1 29 1.3E-15 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS21320 525c6625ff608ad620516491b6269628 419 Pfam PF01593 Flavin containing amine oxidoreductase 1 277 2.9E-14 T 06-07-2017 IPR002937 Amine oxidase GO:0016491|GO:0055114 CAK77_RS21320 525c6625ff608ad620516491b6269628 419 SUPERFAMILY SSF51905 369 400 1.75E-35 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS21320 525c6625ff608ad620516491b6269628 419 SUPERFAMILY SSF51905 1 291 1.75E-35 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS19365 e1c4f122c9357f11e1803bbd39b6361c 488 Pfam PF01636 Phosphotransferase enzyme family 318 354 2.5E-6 T 06-07-2017 IPR002575 Aminoglycoside phosphotransferase CAK77_RS19365 e1c4f122c9357f11e1803bbd39b6361c 488 Gene3D G3DSA:3.90.1200.10 309 354 2.3E-8 T 06-07-2017 CAK77_RS19365 e1c4f122c9357f11e1803bbd39b6361c 488 Pfam PF03109 ABC1 family 151 270 1.1E-33 T 06-07-2017 IPR004147 UbiB domain CAK77_RS19365 e1c4f122c9357f11e1803bbd39b6361c 488 SUPERFAMILY SSF56112 134 196 2.59E-30 T 06-07-2017 IPR011009 Protein kinase-like domain CAK77_RS19365 e1c4f122c9357f11e1803bbd39b6361c 488 SUPERFAMILY SSF56112 236 368 2.59E-30 T 06-07-2017 IPR011009 Protein kinase-like domain CAK77_RS07250 a856ed2f18e7eb5d89d584590e662103 405 Pfam PF00953 Glycosyl transferase family 4 96 260 1.0E-33 T 06-07-2017 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 CAK77_RS22490 761bff41d50cd34c5b9ea1e02f2aec85 285 Pfam PF02405 Permease MlaE 64 275 6.2E-57 T 06-07-2017 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 CAK77_RS03320 5d57c795f69e7246604c8d11b9992551 125 Gene3D G3DSA:3.10.180.10 1 124 8.8E-31 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK77_RS03320 5d57c795f69e7246604c8d11b9992551 125 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 2 120 7.1E-11 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CAK77_RS03320 5d57c795f69e7246604c8d11b9992551 125 SUPERFAMILY SSF54593 2 124 9.53E-24 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAK77_RS11770 436d6246966c7374bb4b00ad312d0527 110 TIGRFAM TIGR00192 urease_beta: urease, beta subunit 4 104 4.8E-37 T 06-07-2017 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAK77_RS11770 436d6246966c7374bb4b00ad312d0527 110 Gene3D G3DSA:2.10.150.10 4 106 8.3E-44 T 06-07-2017 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAK77_RS11770 436d6246966c7374bb4b00ad312d0527 110 SUPERFAMILY SSF51278 4 107 1.06E-42 T 06-07-2017 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAK77_RS11770 436d6246966c7374bb4b00ad312d0527 110 Pfam PF00699 Urease beta subunit 6 101 1.1E-39 T 06-07-2017 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAK77_RS11770 436d6246966c7374bb4b00ad312d0527 110 Hamap MF_01954 Urease subunit beta [ureB]. 4 104 29.6 T 06-07-2017 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAK77_RS22730 6711bde74f47ecd961a8cfd64d66742e 351 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 13 267 2.3E-53 T 06-07-2017 IPR005693 Virulence factor Mce protein CAK77_RS22730 6711bde74f47ecd961a8cfd64d66742e 351 Pfam PF02470 MlaD protein 37 111 5.8E-16 T 06-07-2017 IPR003399 Mce/MlaD CAK77_RS01320 d51d312d9db59511cdd30fc6ad69b4b2 126 Pfam PF06305 Protein of unknown function (DUF1049) 72 122 2.3E-10 T 06-07-2017 IPR010445 Lipopolysaccharide assembly protein A domain GO:0005887 CAK77_RS13185 931275902833a3b2fa963a82f9798afb 726 Pfam PF01757 Acyltransferase family 35 369 1.1E-18 T 06-07-2017 IPR002656 Acyltransferase 3 GO:0016747 CAK77_RS14010 8010072b41773e5e800468b7f4e74493 302 Pfam PF04087 Domain of unknown function (DUF389) 145 288 3.2E-27 T 06-07-2017 IPR005240 Protein of unknown function DUF389 CAK77_RS15885 e00590a07438d4f4577198e1671ec261 461 Gene3D G3DSA:3.20.20.80 36 425 5.2E-75 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAK77_RS15885 e00590a07438d4f4577198e1671ec261 461 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 38 52 - T 06-07-2017 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site CAK77_RS15885 e00590a07438d4f4577198e1671ec261 461 SUPERFAMILY SSF51445 36 425 3.72E-84 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily CAK77_RS15885 e00590a07438d4f4577198e1671ec261 461 Pfam PF00232 Glycosyl hydrolase family 1 36 237 9.5E-35 T 06-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CAK77_RS15885 e00590a07438d4f4577198e1671ec261 461 Pfam PF00232 Glycosyl hydrolase family 1 296 423 2.9E-17 T 06-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CAK77_RS15885 e00590a07438d4f4577198e1671ec261 461 PRINTS PR00131 Glycosyl hydrolase family 1 signature 392 404 2.9E-12 T 06-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CAK77_RS15885 e00590a07438d4f4577198e1671ec261 461 PRINTS PR00131 Glycosyl hydrolase family 1 signature 278 292 2.9E-12 T 06-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CAK77_RS15885 e00590a07438d4f4577198e1671ec261 461 PRINTS PR00131 Glycosyl hydrolase family 1 signature 330 338 2.9E-12 T 06-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CAK77_RS15885 e00590a07438d4f4577198e1671ec261 461 PRINTS PR00131 Glycosyl hydrolase family 1 signature 369 386 2.9E-12 T 06-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CAK77_RS23670 1c30b128e9d7916872f6ae69cbd6b4f5 312 Gene3D G3DSA:3.40.1090.10 16 171 7.6E-8 T 06-07-2017 CAK77_RS23670 1c30b128e9d7916872f6ae69cbd6b4f5 312 SUPERFAMILY SSF52151 221 306 2.88E-47 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAK77_RS23670 1c30b128e9d7916872f6ae69cbd6b4f5 312 SUPERFAMILY SSF52151 10 188 2.88E-47 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAK77_RS23670 1c30b128e9d7916872f6ae69cbd6b4f5 312 Pfam PF01734 Patatin-like phospholipase 16 168 8.1E-18 T 06-07-2017 IPR002641 Patatin/Phospholipase A2-related GO:0006629 CAK77_RS16925 2f528095949cf089f95155ee330c06ca 109 Pfam PF11829 Protein of unknown function (DUF3349) 6 100 6.0E-35 T 06-07-2017 IPR021784 Protein of unknown function DUF3349 CAK77_RS16625 c6ed5340a6f5ce4a1abaa4bbfbf7f987 218 SUPERFAMILY SSF55021 3 71 1.37E-6 T 06-07-2017 CAK77_RS07310 4cb1865a77d1c75556612bd2c5118c82 417 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 406 7.5E-113 T 06-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 CAK77_RS07310 4cb1865a77d1c75556612bd2c5118c82 417 Gene3D G3DSA:3.65.10.10 22 220 1.1E-64 T 06-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 CAK77_RS07310 4cb1865a77d1c75556612bd2c5118c82 417 Gene3D G3DSA:3.65.10.10 221 416 1.5E-52 T 06-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 CAK77_RS07310 4cb1865a77d1c75556612bd2c5118c82 417 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 2 416 41.652 T 06-07-2017 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK77_RS07310 4cb1865a77d1c75556612bd2c5118c82 417 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 4 415 8.7E-168 T 06-07-2017 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAK77_RS07310 4cb1865a77d1c75556612bd2c5118c82 417 SUPERFAMILY SSF55205 4 416 3.76E-132 T 06-07-2017 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 CAK77_RS09135 e723572eb4b09ae51d09062756c213dc 212 ProDom PD034336 YITP MEMBRANE YVAW TRANSMEMBRANE 59 191 1.0E-9 T 06-07-2017 IPR023902 Sporulation delaying protein SdpA CAK77_RS09135 e723572eb4b09ae51d09062756c213dc 212 TIGRFAM TIGR04034 export_SdpA: antimicrobial peptide system protein, SdpA family 35 195 5.3E-27 T 06-07-2017 IPR023902 Sporulation delaying protein SdpA CAK77_RS00565 99ee117c6274b2343628af37cca3cfd9 229 Pfam PF03551 Transcriptional regulator PadR-like family 19 94 5.5E-9 T 06-07-2017 IPR005149 Transcription regulator PadR, N-terminal CAK77_RS00565 99ee117c6274b2343628af37cca3cfd9 229 SUPERFAMILY SSF46785 16 187 1.58E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS00565 99ee117c6274b2343628af37cca3cfd9 229 Gene3D G3DSA:1.10.10.10 15 99 3.6E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS23735 07ee9ec94df8fca193673abbbb9ab1b3 311 Pfam PF10118 Predicted metal-dependent hydrolase 6 200 2.1E-37 T 06-07-2017 IPR016516 Uncharacterised conserved protein UCP07580 CAK77_RS14740 62876997c0b3eb307935f6cdc359218f 166 Gene3D G3DSA:3.10.450.50 6 108 4.0E-11 T 06-07-2017 IPR032710 NTF2-like domain CAK77_RS14740 62876997c0b3eb307935f6cdc359218f 166 SUPERFAMILY SSF54427 2 134 1.57E-21 T 06-07-2017 IPR032710 NTF2-like domain CAK77_RS14740 62876997c0b3eb307935f6cdc359218f 166 Pfam PF12680 SnoaL-like domain 26 118 6.0E-8 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain CAK77_RS06110 eb19928259c6ae5bb1da6effd3aeec92 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 47 70 7.6E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS06110 eb19928259c6ae5bb1da6effd3aeec92 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 39 7.6E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS06110 eb19928259c6ae5bb1da6effd3aeec92 195 Gene3D G3DSA:1.10.357.10 12 191 4.0E-21 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS06110 eb19928259c6ae5bb1da6effd3aeec92 195 SUPERFAMILY SSF46689 14 78 4.69E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS06110 eb19928259c6ae5bb1da6effd3aeec92 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 72 4.3E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS19230 6b12953e0d154508383a0e0e8faeaef2 126 Pfam PF11259 Protein of unknown function (DUF3060) 56 114 5.0E-21 T 06-07-2017 IPR021417 Protein of unknown function DUF3060 CAK77_RS20650 3059f8fc0f8dfd077893af27971efa87 329 Gene3D G3DSA:3.20.20.100 8 313 2.0E-107 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAK77_RS20650 3059f8fc0f8dfd077893af27971efa87 329 Pfam PF00248 Aldo/keto reductase family 14 308 5.6E-73 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAK77_RS20650 3059f8fc0f8dfd077893af27971efa87 329 SUPERFAMILY SSF51430 1 309 5.37E-96 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAK77_RS20650 3059f8fc0f8dfd077893af27971efa87 329 PRINTS PR00069 Aldo-keto reductase signature 245 269 1.8E-5 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAK77_RS20650 3059f8fc0f8dfd077893af27971efa87 329 PRINTS PR00069 Aldo-keto reductase signature 112 130 1.8E-5 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAK77_RS20650 3059f8fc0f8dfd077893af27971efa87 329 PRINTS PR00069 Aldo-keto reductase signature 46 70 1.8E-5 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAK77_RS24100 5e98b4d8fe6a3956ea41b2b47ba78a06 543 PIRSF PIRSF010361 23 511 5.0E-170 T 06-07-2017 IPR016570 Uncharacterised conserved protein UCP010361, membrane CAK77_RS24100 5e98b4d8fe6a3956ea41b2b47ba78a06 543 Pfam PF09594 Protein of unknown function (DUF2029) 179 409 9.2E-15 T 06-07-2017 IPR018584 Glycosyltransferase family 87 GO:0016758 CAK77_RS17635 b43dedec445458727645509ce66a6290 117 Pfam PF13806 Rieske-like [2Fe-2S] domain 2 104 3.0E-33 T 06-07-2017 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 CAK77_RS17635 b43dedec445458727645509ce66a6290 117 SUPERFAMILY SSF50022 2 106 7.75E-31 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK77_RS17635 b43dedec445458727645509ce66a6290 117 TIGRFAM TIGR02378 nirD_assim_sml: nitrite reductase [NAD(P)H], small subunit 2 104 2.2E-26 T 06-07-2017 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 CAK77_RS17635 b43dedec445458727645509ce66a6290 117 Gene3D G3DSA:2.102.10.10 2 108 5.3E-36 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAK77_RS11645 813fe9e1eb9470b936d31b0b3dfcc37f 322 Pfam PF05949 Bacterial protein of unknown function (DUF881) 161 315 2.5E-35 T 06-07-2017 IPR010273 Protein of unknown function DUF881 CAK77_RS16965 224117352d7d1c2951040b4e1c2a0f98 119 Gene3D G3DSA:1.10.8.290 2 116 6.7E-51 T 06-07-2017 IPR023204 SP1917 domain CAK77_RS16965 224117352d7d1c2951040b4e1c2a0f98 119 Pfam PF09966 Uncharacterized protein conserved in bacteria (DUF2200) 4 113 7.0E-48 T 06-07-2017 IPR014580 Uncharacterised conserved protein UCP033199 CAK77_RS12295 752e6d1d77be941e51d5065601a4d034 138 Gene3D G3DSA:1.10.720.10 102 127 8.5E-4 T 06-07-2017 CAK77_RS12295 752e6d1d77be941e51d5065601a4d034 138 Pfam PF06150 ChaB 15 69 3.5E-18 T 06-07-2017 IPR009317 ChaB CAK77_RS12295 752e6d1d77be941e51d5065601a4d034 138 Pfam PF07498 Rho termination factor, N-terminal domain 103 130 3.8E-6 T 06-07-2017 IPR011112 Rho termination factor, N-terminal GO:0006353 CAK77_RS12295 752e6d1d77be941e51d5065601a4d034 138 SUPERFAMILY SSF140376 11 69 9.42E-16 T 06-07-2017 CAK77_RS06500 079998c579a95d59469048351791af5d 432 Pfam PF01757 Acyltransferase family 24 351 6.8E-12 T 06-07-2017 IPR002656 Acyltransferase 3 GO:0016747 CAK77_RS06740 f669d23bcd8c407955c85c526512c2a5 325 Gene3D G3DSA:3.40.50.720 5 293 6.4E-39 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS06740 f669d23bcd8c407955c85c526512c2a5 325 SUPERFAMILY SSF51735 2 295 4.97E-46 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS06740 f669d23bcd8c407955c85c526512c2a5 325 Pfam PF01370 NAD dependent epimerase/dehydratase family 7 178 4.8E-24 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 CAK77_RS14245 a8c1a1fbd124e50db294446c521aa4bf 492 Pfam PF03055 Retinal pigment epithelial membrane protein 19 489 3.9E-95 T 06-07-2017 IPR004294 Carotenoid oxygenase GO:0016702|GO:0055114 CAK77_RS13305 02a377b681d620e2e89c5634e7fe3cfa 576 Pfam PF01566 Natural resistance-associated macrophage protein 90 448 2.5E-78 T 06-07-2017 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CAK77_RS11120 452ee341e1d30d9176600e2cda2b135b 251 SUPERFAMILY SSF109604 63 185 6.0E-16 T 06-07-2017 CAK77_RS11120 452ee341e1d30d9176600e2cda2b135b 251 Pfam PF01966 HD domain 75 162 6.9E-5 T 06-07-2017 IPR006674 HD domain CAK77_RS11120 452ee341e1d30d9176600e2cda2b135b 251 Gene3D G3DSA:1.10.3210.10 64 182 2.2E-10 T 06-07-2017 IPR006674 HD domain CAK77_RS09130 1c818d2e425b4528a7145b056db28ba8 385 Pfam PF13630 SdpI/YhfL protein family 34 110 1.4E-8 T 06-07-2017 IPR025962 SdpI/YhfL protein family CAK77_RS10090 7a4748ea9dba671ff3e633fbf91976a1 217 SUPERFAMILY SSF54001 16 159 2.24E-16 T 06-07-2017 CAK77_RS10090 7a4748ea9dba671ff3e633fbf91976a1 217 Pfam PF01841 Transglutaminase-like superfamily 30 139 2.0E-13 T 06-07-2017 IPR002931 Transglutaminase-like CAK77_RS13660 e5fcf9e65bfd945b3e68df2290717a86 150 Pfam PF10756 Bacterial PH domain 73 142 5.3E-23 T 06-07-2017 IPR019692 Protein of unknown function DUF2581 CAK77_RS08645 c31996d64b4833e615813afd6071e9d0 355 Pfam PF02470 MlaD protein 40 112 1.5E-14 T 06-07-2017 IPR003399 Mce/MlaD CAK77_RS08645 c31996d64b4833e615813afd6071e9d0 355 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 14 268 3.1E-53 T 06-07-2017 IPR005693 Virulence factor Mce protein CAK77_RS01995 c0eb2b53cb70407897ca042594181ec4 202 SUPERFAMILY SSF81995 3 50 4.18E-6 T 06-07-2017 CAK77_RS02525 9b31d5d6c1654209534bef10f640ad24 120 Pfam PF13239 2TM domain 37 90 4.4E-9 T 06-07-2017 IPR025698 2TM domain CAK77_RS23140 6b166caf08c45026047036c103bc262f 184 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 54 179 4.6E-7 T 06-07-2017 IPR019587 Polyketide cyclase/dehydrase CAK77_RS23140 6b166caf08c45026047036c103bc262f 184 SUPERFAMILY SSF55961 56 181 9.95E-7 T 06-07-2017 CAK77_RS23140 6b166caf08c45026047036c103bc262f 184 Gene3D G3DSA:3.30.530.20 56 175 2.7E-4 T 06-07-2017 IPR023393 START-like domain CAK77_RS19790 332b73de1020e9bf2b60626d1360ea6e 144 Pfam PF11829 Protein of unknown function (DUF3349) 35 122 1.6E-34 T 06-07-2017 IPR021784 Protein of unknown function DUF3349 CAK77_RS24205 8d5268824934cf52cea23f67314e989e 387 Pfam PF04235 Protein of unknown function (DUF418) 227 377 2.9E-28 T 06-07-2017 IPR007349 Domain of unknown function DUF418 CAK77_RS17145 f89cc9f800987a642bbc1eebc3c282fa 122 Pfam PF11964 SpoIIAA-like 12 120 2.5E-14 T 06-07-2017 IPR021866 SpoIIAA-like CAK77_RS17145 f89cc9f800987a642bbc1eebc3c282fa 122 Gene3D G3DSA:3.40.50.10600 1 119 1.6E-29 T 06-07-2017 IPR021866 SpoIIAA-like CAK77_RS17145 f89cc9f800987a642bbc1eebc3c282fa 122 SUPERFAMILY SSF52091 1 119 1.53E-26 T 06-07-2017 IPR002645 STAS domain CAK77_RS18775 0f072c93266a499283b38b2bc2c7d19f 329 Gene3D G3DSA:3.40.50.1820 4 183 1.4E-78 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS18775 0f072c93266a499283b38b2bc2c7d19f 329 Gene3D G3DSA:3.40.50.1820 217 325 1.4E-78 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS18775 0f072c93266a499283b38b2bc2c7d19f 329 Pfam PF00561 alpha/beta hydrolase fold 27 128 4.8E-16 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS18775 0f072c93266a499283b38b2bc2c7d19f 329 SUPERFAMILY SSF53474 5 185 2.06E-65 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS18775 0f072c93266a499283b38b2bc2c7d19f 329 SUPERFAMILY SSF53474 217 325 2.06E-65 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS18775 0f072c93266a499283b38b2bc2c7d19f 329 PRINTS PR00412 Epoxide hydrolase signature 113 126 1.1E-30 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK77_RS18775 0f072c93266a499283b38b2bc2c7d19f 329 PRINTS PR00412 Epoxide hydrolase signature 263 279 1.1E-30 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK77_RS18775 0f072c93266a499283b38b2bc2c7d19f 329 PRINTS PR00412 Epoxide hydrolase signature 33 51 1.1E-30 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK77_RS18775 0f072c93266a499283b38b2bc2c7d19f 329 PRINTS PR00412 Epoxide hydrolase signature 300 322 1.1E-30 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK77_RS18775 0f072c93266a499283b38b2bc2c7d19f 329 PRINTS PR00412 Epoxide hydrolase signature 99 112 1.1E-30 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK77_RS18775 0f072c93266a499283b38b2bc2c7d19f 329 PRINTS PR00412 Epoxide hydrolase signature 53 68 1.1E-30 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAK77_RS02110 182a19a730b81aa9a817911dd6df711e 79 Gene3D G3DSA:1.10.260.40 39 70 2.6E-4 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK77_RS11950 0d58c593f55246c94984f3f46c6e78a8 345 Gene3D G3DSA:1.10.540.10 3 94 2.8E-5 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAK77_RS11950 0d58c593f55246c94984f3f46c6e78a8 345 SUPERFAMILY SSF56645 11 206 1.07E-20 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAK77_RS11950 0d58c593f55246c94984f3f46c6e78a8 345 Gene3D G3DSA:2.40.110.10 117 206 4.1E-11 T 06-07-2017 CAK77_RS07255 d990e46f6ab267f31d4af1ec86c9bac7 148 Pfam PF03899 ATP synthase I chain 29 115 1.9E-5 T 06-07-2017 IPR005598 ATP synthase protein I CAK77_RS19880 c1bcafedf4e0bb6065123f4f022cc914 418 SUPERFAMILY SSF52540 234 368 4.18E-28 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS19880 c1bcafedf4e0bb6065123f4f022cc914 418 SUPERFAMILY SSF52540 108 151 4.18E-28 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS19880 c1bcafedf4e0bb6065123f4f022cc914 418 Gene3D G3DSA:3.40.50.300 244 367 1.5E-12 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS19880 c1bcafedf4e0bb6065123f4f022cc914 418 Gene3D G3DSA:3.40.50.300 108 168 1.5E-12 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS19880 c1bcafedf4e0bb6065123f4f022cc914 418 Pfam PF13469 Sulfotransferase family 112 357 3.8E-43 T 06-07-2017 CAK77_RS20095 abe6596bd7782a82274df9fad5fa5af1 281 SUPERFAMILY SSF51658 13 278 1.66E-42 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain CAK77_RS20095 abe6596bd7782a82274df9fad5fa5af1 281 Pfam PF01261 Xylose isomerase-like TIM barrel 23 230 1.5E-16 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain CAK77_RS20095 abe6596bd7782a82274df9fad5fa5af1 281 Gene3D G3DSA:3.20.20.150 3 279 2.2E-45 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain CAK77_RS04590 99148bd7d2c14ae9a5cf503a94b84dc0 217 Pfam PF11139 Sap, sulfolipid-1-addressing protein 5 214 8.1E-68 T 06-07-2017 IPR021315 Glycolipid exporter Gap/Sap CAK77_RS01525 13db2463ce21d07eeac33ac99eb46fda 211 Gene3D G3DSA:3.40.50.850 5 210 2.6E-59 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAK77_RS01525 13db2463ce21d07eeac33ac99eb46fda 211 SUPERFAMILY SSF52499 5 210 4.84E-61 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAK77_RS01525 13db2463ce21d07eeac33ac99eb46fda 211 PIRSF PIRSF001111 6 211 7.4E-92 T 06-07-2017 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 CAK77_RS01525 13db2463ce21d07eeac33ac99eb46fda 211 Pfam PF00857 Isochorismatase family 37 204 1.3E-33 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAK77_RS01525 13db2463ce21d07eeac33ac99eb46fda 211 PRINTS PR01398 Isochorismatase signature 115 137 4.3E-48 T 06-07-2017 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 CAK77_RS01525 13db2463ce21d07eeac33ac99eb46fda 211 PRINTS PR01398 Isochorismatase signature 83 102 4.3E-48 T 06-07-2017 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 CAK77_RS01525 13db2463ce21d07eeac33ac99eb46fda 211 PRINTS PR01398 Isochorismatase signature 66 83 4.3E-48 T 06-07-2017 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 CAK77_RS01525 13db2463ce21d07eeac33ac99eb46fda 211 PRINTS PR01398 Isochorismatase signature 171 189 4.3E-48 T 06-07-2017 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 CAK77_RS01525 13db2463ce21d07eeac33ac99eb46fda 211 PRINTS PR01398 Isochorismatase signature 189 206 4.3E-48 T 06-07-2017 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 CAK77_RS01525 13db2463ce21d07eeac33ac99eb46fda 211 PRINTS PR01398 Isochorismatase signature 7 19 4.3E-48 T 06-07-2017 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 CAK77_RS01610 f7bc4c1110cf556d106939c1048a6372 273 Gene3D G3DSA:3.90.226.10 11 255 2.5E-39 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS01610 f7bc4c1110cf556d106939c1048a6372 273 SUPERFAMILY SSF52096 11 255 1.81E-43 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS01610 f7bc4c1110cf556d106939c1048a6372 273 Pfam PF00378 Enoyl-CoA hydratase/isomerase 45 255 1.1E-18 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAK77_RS03405 6ffa9d7c0e95b171d212f15f3171a253 350 SUPERFAMILY SSF53300 84 209 5.0E-5 T 06-07-2017 IPR002035 von Willebrand factor, type A CAK77_RS10885 1ea04346487346c31e52287046f66e0b 521 Pfam PF05108 Type VII secretion system ESX-1, transport TM domain B 34 498 3.8E-158 T 06-07-2017 IPR007795 Type VII secretion system EccB CAK77_RS10885 1ea04346487346c31e52287046f66e0b 521 TIGRFAM TIGR03919 T7SS_EccB: type VII secretion protein EccB 37 486 9.8E-157 T 06-07-2017 IPR007795 Type VII secretion system EccB CAK77_RS08950 c0f8046703b4d841b8e86a0a9aaec0d8 194 SUPERFAMILY SSF46689 10 83 6.16E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS08950 c0f8046703b4d841b8e86a0a9aaec0d8 194 Gene3D G3DSA:1.10.357.10 12 161 8.1E-21 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS08950 c0f8046703b4d841b8e86a0a9aaec0d8 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 63 7.2E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS02225 2fcfab49aefb3650950dc2f688119840 221 Pfam PF13392 HNH endonuclease 69 113 7.4E-8 T 06-07-2017 IPR003615 HNH nuclease CAK77_RS02225 2fcfab49aefb3650950dc2f688119840 221 SUPERFAMILY SSF54060 31 121 6.47E-13 T 06-07-2017 CAK77_RS11110 49f7239ade5dc06b74e445008aa3bea7 439 Pfam PF00999 Sodium/hydrogen exchanger family 25 418 7.4E-51 T 06-07-2017 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CAK77_RS09965 5db159febbc9663df3e12fcdec5addac 388 Gene3D G3DSA:3.40.47.10 259 361 8.4E-9 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS09965 5db159febbc9663df3e12fcdec5addac 388 SUPERFAMILY SSF53901 21 231 5.47E-18 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS09965 5db159febbc9663df3e12fcdec5addac 388 Gene3D G3DSA:3.40.47.10 196 226 2.1E-13 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS09965 5db159febbc9663df3e12fcdec5addac 388 Gene3D G3DSA:3.40.47.10 23 114 2.1E-13 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS09965 5db159febbc9663df3e12fcdec5addac 388 SUPERFAMILY SSF53901 258 376 1.43E-19 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAK77_RS07570 b15ab3eadbd4fc1f9c101c236a3da24a 265 Gene3D G3DSA:1.10.3720.10 12 261 5.3E-39 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS07570 b15ab3eadbd4fc1f9c101c236a3da24a 265 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 254 1.4E-14 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS07570 b15ab3eadbd4fc1f9c101c236a3da24a 265 SUPERFAMILY SSF161098 6 256 9.42E-42 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS21195 94e806d55d1f2bb21cb4df21bdd562c5 116 Pfam PF04075 Domain of unknown function (DUF385) 21 77 8.9E-5 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CAK77_RS01985 25a5c68adc3d8ca78693e2e800072aa6 442 Pfam PF02720 Domain of unknown function (DUF222) 28 354 1.4E-85 T 06-07-2017 IPR003870 Domain of unknown function DUF222 CAK77_RS01985 25a5c68adc3d8ca78693e2e800072aa6 442 Pfam PF01844 HNH endonuclease 367 392 1.4E-4 T 06-07-2017 IPR002711 HNH endonuclease GO:0003676|GO:0004519 CAK77_RS01985 25a5c68adc3d8ca78693e2e800072aa6 442 SMART SM00507 345 397 1.5E-8 T 06-07-2017 IPR003615 HNH nuclease CAK77_RS02595 7eda76337109b305daf094c4d0bf8557 230 Pfam PF11139 Sap, sulfolipid-1-addressing protein 10 220 1.0E-18 T 06-07-2017 IPR021315 Glycolipid exporter Gap/Sap CAK77_RS08840 14be08b5e6a6cc543d897d4591d1eaee 265 SUPERFAMILY SSF49899 22 265 4.35E-43 T 06-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain CAK77_RS08840 14be08b5e6a6cc543d897d4591d1eaee 265 Gene3D G3DSA:2.60.120.200 17 265 8.1E-42 T 06-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain CAK77_RS08840 14be08b5e6a6cc543d897d4591d1eaee 265 Pfam PF00722 Glycosyl hydrolases family 16 83 207 6.5E-14 T 06-07-2017 IPR000757 Glycoside hydrolase family 16 GO:0004553|GO:0005975 CAK77_RS13295 fc9786ab8e9e0d32e83aca4a593b8fc2 125 Pfam PF13564 DoxX-like family 13 110 4.3E-10 T 06-07-2017 IPR032808 DoxX family CAK77_RS18300 f74142ae9f55cce9e067f70597ce9c1a 160 Gene3D G3DSA:1.20.950.10 27 158 2.4E-45 T 06-07-2017 CAK77_RS18300 f74142ae9f55cce9e067f70597ce9c1a 160 SUPERFAMILY SSF81343 36 156 2.83E-31 T 06-07-2017 CAK77_RS18300 f74142ae9f55cce9e067f70597ce9c1a 160 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 34 146 7.0E-18 T 06-07-2017 IPR000701 Succinate dehydrogenase/Fumarate reductase, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAK77_RS13470 63ce34440b57ee0b4011166c895841cc 475 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 20 466 4.6E-219 T 06-07-2017 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 CAK77_RS13470 63ce34440b57ee0b4011166c895841cc 475 SUPERFAMILY SSF101960 42 472 4.45E-140 T 06-07-2017 CAK77_RS13470 63ce34440b57ee0b4011166c895841cc 475 Pfam PF01458 Uncharacterized protein family (UPF0051) 221 446 2.3E-76 T 06-07-2017 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 CAK77_RS05885 1d1009db7f64addc6597fd79dd5f86f9 149 Pfam PF13643 Domain of unknown function (DUF4145) 31 118 4.7E-19 T 06-07-2017 IPR025285 Domain of unknown function DUF4145 CAK77_RS10750 964027c879b9800266b6271ef499249c 253 Gene3D G3DSA:3.90.550.10 14 221 1.1E-25 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK77_RS10750 964027c879b9800266b6271ef499249c 253 SUPERFAMILY SSF53448 11 226 3.28E-42 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAK77_RS10750 964027c879b9800266b6271ef499249c 253 Pfam PF00535 Glycosyl transferase family 2 14 180 7.6E-30 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CAK77_RS01170 3277125630baf2d69a37fc6d412444fb 295 Pfam PF01061 ABC-2 type transporter 49 255 1.4E-24 T 06-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CAK77_RS00950 8415bb528690726038670c87361d904c 145 Gene3D G3DSA:1.10.10.10 22 134 1.9E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS00950 8415bb528690726038670c87361d904c 145 SMART SM00347 23 123 6.1E-13 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK77_RS00950 8415bb528690726038670c87361d904c 145 SUPERFAMILY SSF46785 18 134 4.34E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS00950 8415bb528690726038670c87361d904c 145 Pfam PF01047 MarR family 34 87 2.0E-12 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK77_RS00950 8415bb528690726038670c87361d904c 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 83 99 1.1E-5 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK77_RS00950 8415bb528690726038670c87361d904c 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 64 79 1.1E-5 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAK77_RS13990 698afcebbbe711fbde9d818981f8787d 148 Pfam PF04075 Domain of unknown function (DUF385) 23 143 2.1E-36 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CAK77_RS13990 698afcebbbe711fbde9d818981f8787d 148 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 34 146 1.7E-30 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CAK77_RS20045 1b1545f81159775e0b25f4b10e948931 357 SMART SM00563 143 262 4.4E-20 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CAK77_RS20045 1b1545f81159775e0b25f4b10e948931 357 Pfam PF01553 Acyltransferase 128 259 9.7E-17 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CAK77_RS20045 1b1545f81159775e0b25f4b10e948931 357 SUPERFAMILY SSF69593 117 350 3.66E-37 T 06-07-2017 CAK77_RS16505 707fd2dfa60b10b3cc305f7d544566ee 143 Pfam PF10825 Protein of unknown function (DUF2752) 45 92 1.1E-19 T 06-07-2017 IPR021215 Protein of unknown function DUF2752 CAK77_RS18170 0c0291cc3add91b1030b045f6a7427de 435 SMART SM01150 11 383 5.2E-172 T 06-07-2017 IPR009770 Domain of unknown function DUF1338 CAK77_RS18170 0c0291cc3add91b1030b045f6a7427de 435 Pfam PF07063 Domain of unknown function (DUF1338) 9 383 3.1E-98 T 06-07-2017 IPR009770 Domain of unknown function DUF1338 CAK77_RS09300 b6d48bf417a0f28c863f9b8942f09e6b 509 SUPERFAMILY SSF53474 191 471 1.03E-19 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS09300 b6d48bf417a0f28c863f9b8942f09e6b 509 SUPERFAMILY SSF53474 95 145 1.03E-19 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS09300 b6d48bf417a0f28c863f9b8942f09e6b 509 Pfam PF00561 alpha/beta hydrolase fold 96 485 7.2E-56 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS09300 b6d48bf417a0f28c863f9b8942f09e6b 509 Gene3D G3DSA:3.40.50.1820 376 497 2.2E-49 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS09300 b6d48bf417a0f28c863f9b8942f09e6b 509 Gene3D G3DSA:3.40.50.1820 193 316 2.2E-49 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS09300 b6d48bf417a0f28c863f9b8942f09e6b 509 Gene3D G3DSA:3.40.50.1820 63 147 2.2E-49 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS14155 ef71d21307af883976d0506fbdc052e3 340 ProSitePatterns PS00893 Nudix box signature. 212 233 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CAK77_RS14155 ef71d21307af883976d0506fbdc052e3 340 Pfam PF00293 NUDIX domain 174 311 5.2E-17 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 CAK77_RS14155 ef71d21307af883976d0506fbdc052e3 340 SUPERFAMILY SSF55811 178 311 1.16E-18 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAK77_RS14155 ef71d21307af883976d0506fbdc052e3 340 Gene3D G3DSA:3.90.79.10 173 314 5.6E-21 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAK77_RS18665 653cc6fea6ad375bcb46af733f7d4464 310 Pfam PF12697 Alpha/beta hydrolase family 72 295 4.3E-14 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS18665 653cc6fea6ad375bcb46af733f7d4464 310 Gene3D G3DSA:3.40.50.1820 35 305 2.2E-41 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS18665 653cc6fea6ad375bcb46af733f7d4464 310 SUPERFAMILY SSF53474 55 305 2.43E-37 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS18375 1654ffd624cf1c058aac656121e4a883 245 Gene3D G3DSA:3.40.50.150 24 224 5.7E-30 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS18375 1654ffd624cf1c058aac656121e4a883 245 SUPERFAMILY SSF53335 12 144 3.59E-34 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS18375 1654ffd624cf1c058aac656121e4a883 245 Pfam PF08241 Methyltransferase domain 43 131 1.2E-21 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CAK77_RS07420 03d8bd208bf936abf09a3fc55a2e4bbe 100 SUPERFAMILY SSF54736 22 97 2.77E-23 T 06-07-2017 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like CAK77_RS07420 03d8bd208bf936abf09a3fc55a2e4bbe 100 Pfam PF02617 ATP-dependent Clp protease adaptor protein ClpS 23 94 1.6E-21 T 06-07-2017 IPR003769 Adaptor protein ClpS, core GO:0030163 Reactome: R-HSA-983168 CAK77_RS07420 03d8bd208bf936abf09a3fc55a2e4bbe 100 Hamap MF_00302 ATP-dependent Clp protease adapter protein ClpS [clpS]. 12 100 16.874 T 06-07-2017 IPR022935 ATP-dependent Clp protease adaptor protein ClpS CAK77_RS07420 03d8bd208bf936abf09a3fc55a2e4bbe 100 Gene3D G3DSA:3.30.1390.10 9 99 1.3E-28 T 06-07-2017 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like CAK77_RS06365 acc148d58f609063f969f28c00383efa 161 Pfam PF03703 Bacterial PH domain 74 136 1.0E-9 T 06-07-2017 IPR005182 Domain of unknown function DUF304 CAK77_RS07505 7d1cc2bf7d79dcbcf6e710cc46f10d58 249 Pfam PF13835 Domain of unknown function (DUF4194) 53 211 4.8E-35 T 06-07-2017 IPR025449 Protein of unknown function DUF4194 CAK77_RS02395 2110f7b0146310ba947c0e784daa8c37 353 SUPERFAMILY SSF52540 39 311 3.47E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS02395 2110f7b0146310ba947c0e784daa8c37 353 Gene3D G3DSA:3.40.50.300 165 328 1.1E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS02395 2110f7b0146310ba947c0e784daa8c37 353 TIGRFAM TIGR03819 heli_sec_ATPase: helicase/secretion neighborhood ATPase 5 332 1.1E-145 T 06-07-2017 IPR022399 Helicase/secretion neighbourhood ATPase CAK77_RS02395 2110f7b0146310ba947c0e784daa8c37 353 Gene3D G3DSA:3.30.450.90 55 155 3.2E-17 T 06-07-2017 CAK77_RS02395 2110f7b0146310ba947c0e784daa8c37 353 Pfam PF00437 Type II/IV secretion system protein 58 329 3.2E-68 T 06-07-2017 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 CAK77_RS20620 9be0022735b770268e4b0ccc09d651f4 112 TIGRFAM TIGR04529 MTB_hemophore: hemophore-related protein, Rv0203/Rv1174c family 41 112 1.6E-15 T 06-07-2017 IPR032407 Haemophore, haem-binding GO:0020037 CAK77_RS20620 9be0022735b770268e4b0ccc09d651f4 112 PIRSF PIRSF010611 1 112 2.6E-37 T 06-07-2017 IPR016572 Uncharacterised conserved protein UCP010611 CAK77_RS00365 0947d4dc1a7959ad46d4f84ea4a389fb 900 Pfam PF15607 Bacterial toxin 44 768 861 2.4E-13 T 06-07-2017 IPR028946 Bacterial toxin 44 CAK77_RS01955 cd64b26d46e4f24c767f793b8700ea88 449 Pfam PF01882 Protein of unknown function DUF58 186 279 1.1E-18 T 06-07-2017 IPR002881 Domain of unknown function DUF58 CAK77_RS07765 1305d2ec541154a66253d1ec3d17dda7 312 SMART SM01110 5 225 5.8E-4 T 06-07-2017 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 CAK77_RS07765 1305d2ec541154a66253d1ec3d17dda7 312 Pfam PF01083 Cutinase 90 157 1.5E-5 T 06-07-2017 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 CAK77_RS07765 1305d2ec541154a66253d1ec3d17dda7 312 SUPERFAMILY SSF53474 87 194 8.21E-15 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS07765 1305d2ec541154a66253d1ec3d17dda7 312 SUPERFAMILY SSF53474 8 60 8.21E-15 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS07765 1305d2ec541154a66253d1ec3d17dda7 312 Gene3D G3DSA:3.40.50.1820 74 194 2.2E-12 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS11040 71d07e9d02d115f542206dbb4e8ff809 154 Pfam PF04314 Protein of unknown function (DUF461) 33 136 8.0E-34 T 06-07-2017 IPR007410 DR1885-like metal-binding protein CAK77_RS11040 71d07e9d02d115f542206dbb4e8ff809 154 SUPERFAMILY SSF110087 9 148 4.45E-36 T 06-07-2017 IPR007410 DR1885-like metal-binding protein CAK77_RS08730 11e7958f26504963de97ed53bf627e74 243 Pfam PF01988 VIT family 28 236 3.3E-55 T 06-07-2017 IPR008217 Ccc1 family CAK77_RS14750 4bff903f44c157fc0a4b7cdc05fcf920 106 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 22 95 1.0E-13 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK77_RS14750 4bff903f44c157fc0a4b7cdc05fcf920 106 Gene3D G3DSA:3.10.20.30 11 100 3.5E-23 T 06-07-2017 IPR012675 Beta-grasp domain CAK77_RS14750 4bff903f44c157fc0a4b7cdc05fcf920 106 SUPERFAMILY SSF54292 8 100 4.33E-22 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAK77_RS23855 21eba24418afd7116a02cc0bd557cd81 207 SUPERFAMILY SSF109854 4 123 4.88E-17 T 06-07-2017 CAK77_RS23855 21eba24418afd7116a02cc0bd557cd81 207 Gene3D G3DSA:1.20.120.450 5 47 1.1E-6 T 06-07-2017 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase CAK77_RS23855 21eba24418afd7116a02cc0bd557cd81 207 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 10 185 5.4E-26 T 06-07-2017 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type CAK77_RS23855 21eba24418afd7116a02cc0bd557cd81 207 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 11 97 1.4E-12 T 06-07-2017 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 CAK77_RS18200 7e6102fa0270abcf4af2f115e8b6590a 277 Pfam PF00849 RNA pseudouridylate synthase 76 222 3.9E-20 T 06-07-2017 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAK77_RS18200 7e6102fa0270abcf4af2f115e8b6590a 277 SUPERFAMILY SSF55120 62 271 5.44E-48 T 06-07-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAK77_RS18200 7e6102fa0270abcf4af2f115e8b6590a 277 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 115 129 - T 06-07-2017 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAK77_RS16675 eeb932f3d305c47124ea94e68dee8ca1 481 Pfam PF00860 Permease family 22 432 4.5E-26 T 06-07-2017 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CAK77_RS15795 599f31721979137c0eb062ba17c5480e 112 Pfam PF10939 Protein of unknown function (DUF2631) 28 93 1.5E-25 T 06-07-2017 IPR024341 Protein of unknown function DUF2631 CAK77_RS15795 599f31721979137c0eb062ba17c5480e 112 ProDom PD069408 TRANSMEMBRANE MEMBRANE RV2876/MT2944.1 CGL2017/CG2211 ML1584 POSSIBLE P20 27 112 4.0E-15 T 06-07-2017 IPR024341 Protein of unknown function DUF2631 CAK77_RS22065 f11f0ab20afab9ce4ab5e20646f6f9db 202 SUPERFAMILY SSF55961 61 196 1.02E-9 T 06-07-2017 CAK77_RS22065 f11f0ab20afab9ce4ab5e20646f6f9db 202 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 60 195 4.3E-9 T 06-07-2017 IPR019587 Polyketide cyclase/dehydrase CAK77_RS22065 f11f0ab20afab9ce4ab5e20646f6f9db 202 Gene3D G3DSA:3.30.530.20 62 176 4.8E-5 T 06-07-2017 IPR023393 START-like domain CAK77_RS22485 01137c5d37df4da01769c41bc915a38a 285 Pfam PF02405 Permease MlaE 68 272 2.7E-50 T 06-07-2017 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 CAK77_RS13780 e27386b6b6f307d9b45aecee4a597c75 282 SUPERFAMILY SSF56317 1 279 1.57E-78 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAK77_RS13780 e27386b6b6f307d9b45aecee4a597c75 282 Pfam PF00795 Carbon-nitrogen hydrolase 5 262 7.9E-63 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAK77_RS13780 e27386b6b6f307d9b45aecee4a597c75 282 Gene3D G3DSA:3.60.110.10 3 279 1.8E-85 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAK77_RS03275 25e812ddce6215c1691c79174c2e86bc 192 Pfam PF01899 Na+/H+ ion antiporter subunit 20 165 6.0E-32 T 06-07-2017 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 CAK77_RS15030 8d1d6001e9e5bb7ffa524826828b86c6 221 Pfam PF04116 Fatty acid hydroxylase superfamily 55 198 1.0E-16 T 06-07-2017 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0006633|GO:0016491|GO:0055114 CAK77_RS01130 3f370bb191ce3fb009fad309073a18b1 137 Pfam PF04138 GtrA-like protein 19 134 5.7E-21 T 06-07-2017 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 CAK77_RS02865 42ce3b7703c6a7fb34179b9f3e2f4e96 262 Pfam PF09490 Probable cobalt transporter subunit (CbtA) 3 251 4.0E-69 T 06-07-2017 IPR012666 Cobalt transporter subunit CbtA, putative CAK77_RS10520 329124e3ba2bdecb0466f1baef939713 175 ProDom PD033474 ANTIGEN PRECURSOR SIGNAL LIPOPROTEIN LOW WEIGHT MOLECULAR LPPK MEMBRANE PALMITATE 42 169 3.0E-18 T 06-07-2017 IPR020235 Low molecular weight antigen MTB12 CAK77_RS00775 550feb02a8720380b27bea5cbd8626af 387 Pfam PF14219 Domain of unknown function (DUF4328) 176 325 1.1E-11 T 06-07-2017 IPR025565 Domain of unknown function DUF4328 CAK77_RS07530 e6ed6298988311ed59eec168a1d0aaaf 475 Pfam PF01494 FAD binding domain 2 345 2.9E-73 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 CAK77_RS07530 e6ed6298988311ed59eec168a1d0aaaf 475 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 283 298 2.9E-34 T 06-07-2017 CAK77_RS07530 e6ed6298988311ed59eec168a1d0aaaf 475 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 298 314 2.9E-34 T 06-07-2017 CAK77_RS07530 e6ed6298988311ed59eec168a1d0aaaf 475 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 333 349 2.9E-34 T 06-07-2017 CAK77_RS07530 e6ed6298988311ed59eec168a1d0aaaf 475 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 157 172 2.9E-34 T 06-07-2017 CAK77_RS07530 e6ed6298988311ed59eec168a1d0aaaf 475 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 2.9E-34 T 06-07-2017 CAK77_RS07530 e6ed6298988311ed59eec168a1d0aaaf 475 Gene3D G3DSA:3.50.50.60 101 183 2.9E-56 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS07530 e6ed6298988311ed59eec168a1d0aaaf 475 Gene3D G3DSA:3.50.50.60 1 66 2.9E-56 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS07530 e6ed6298988311ed59eec168a1d0aaaf 475 Gene3D G3DSA:3.50.50.60 271 352 2.9E-56 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS07530 e6ed6298988311ed59eec168a1d0aaaf 475 SUPERFAMILY SSF51905 2 178 2.16E-61 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS07530 e6ed6298988311ed59eec168a1d0aaaf 475 SUPERFAMILY SSF51905 270 357 2.16E-61 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS09190 8b7690ef163ca43bed0cb3c7079e6773 271 Pfam PF02104 SURF1 family 23 225 1.6E-24 T 06-07-2017 IPR002994 Surfeit locus 1/Shy1 GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAK77_RS11020 e7ae4afb81d9ddfb1103e4d57c1b3760 181 TIGRFAM TIGR02406 ectoine_EctA: diaminobutyrate acetyltransferase 19 172 8.7E-45 T 06-07-2017 IPR012772 L-2,4-diaminobutyric acid acetyltransferase GO:0019491|GO:0033816 KEGG: 00250+2.3.1.17|KEGG: 00260+2.3.1.178 CAK77_RS11020 e7ae4afb81d9ddfb1103e4d57c1b3760 181 Pfam PF00583 Acetyltransferase (GNAT) family 62 135 7.9E-8 T 06-07-2017 IPR000182 GNAT domain GO:0008080 CAK77_RS11020 e7ae4afb81d9ddfb1103e4d57c1b3760 181 SUPERFAMILY SSF55729 17 135 8.92E-16 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS11020 e7ae4afb81d9ddfb1103e4d57c1b3760 181 Gene3D G3DSA:3.40.630.30 17 174 1.7E-51 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS13865 41c6c716c2b7806c59ea932351748010 142 Pfam PF04075 Domain of unknown function (DUF385) 17 137 1.0E-32 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CAK77_RS13865 41c6c716c2b7806c59ea932351748010 142 SUPERFAMILY SSF50475 31 140 6.68E-9 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS13865 41c6c716c2b7806c59ea932351748010 142 Gene3D G3DSA:2.30.110.10 35 97 3.5E-5 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS13865 41c6c716c2b7806c59ea932351748010 142 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 27 139 1.3E-28 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CAK77_RS04525 cc84f9dde68a62c0896238223bd3de5e 286 PIRSF PIRSF020623 3 273 3.5E-36 T 06-07-2017 IPR011965 Phenylacetic acid degradation operon negative regulatory protein PaaX GO:0006351 CAK77_RS04525 cc84f9dde68a62c0896238223bd3de5e 286 Pfam PF08223 PaaX-like protein C-terminal domain 99 264 7.0E-27 T 06-07-2017 IPR013225 PaaX-like, C-terminal CAK77_RS04600 02b9a638cad2d896b7ce31bd17dd64a0 388 Pfam PF08237 PE-PPE domain 83 328 1.6E-64 T 06-07-2017 IPR013228 PE-PPE, C-terminal CAK77_RS14675 66204b98b58ef1b6331cb4c7e8e2da07 312 Gene3D G3DSA:3.40.50.1820 84 292 1.6E-25 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS14675 66204b98b58ef1b6331cb4c7e8e2da07 312 Pfam PF12697 Alpha/beta hydrolase family 100 268 5.9E-10 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS14675 66204b98b58ef1b6331cb4c7e8e2da07 312 SUPERFAMILY SSF53474 82 291 3.09E-29 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS22655 b247a7b3667aa57d736ab8b37c47f388 557 Pfam PF12077 Transmembrane protein of unknown function (DUF3556) 1 555 1.6E-267 T 06-07-2017 IPR021941 Protein of unknown function DUF3556, transmembrane CAK77_RS11750 26a05d54c606809b80f437851dff9c9a 251 Pfam PF14032 PknH-like extracellular domain 68 247 3.0E-31 T 06-07-2017 IPR026954 PknH-like extracellular domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 CAK77_RS15535 3cca43b538b28ef49e9c80022ae03e5b 202 Gene3D G3DSA:3.40.630.30 26 201 4.1E-45 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS15535 3cca43b538b28ef49e9c80022ae03e5b 202 Pfam PF13523 Acetyltransferase (GNAT) domain 46 187 1.0E-38 T 06-07-2017 CAK77_RS15535 3cca43b538b28ef49e9c80022ae03e5b 202 SMART SM01006 39 87 4.3E-5 T 06-07-2017 IPR019432 Siderophore biosynthesis protein, conserved domain CAK77_RS15535 3cca43b538b28ef49e9c80022ae03e5b 202 SUPERFAMILY SSF55729 31 201 1.11E-42 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS08640 5a2d9652f8f3c35d25167d5fd00a2f00 502 Pfam PF02470 MlaD protein 52 128 3.1E-9 T 06-07-2017 IPR003399 Mce/MlaD CAK77_RS08640 5a2d9652f8f3c35d25167d5fd00a2f00 502 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 179 367 4.2E-16 T 06-07-2017 IPR024516 Mammalian cell entry, C-terminal CAK77_RS07920 978184682effe62bca097631d598e92e 279 SUPERFAMILY SSF52980 175 274 1.07E-5 T 06-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CAK77_RS14700 f4970c59f3f5032ce569825f72627ea9 122 Gene3D G3DSA:1.10.1510.10 10 122 2.6E-13 T 06-07-2017 CAK77_RS22005 e44c17bfc5ef346ed1e310b4bbe053ad 245 PIRSF PIRSF015736 2 241 5.1E-51 T 06-07-2017 IPR026286 Maleate isomerase/Arylmalonate decarboxylase CAK77_RS09230 dd68452cbe9f6c435aafef67889c1660 348 Pfam PF02720 Domain of unknown function (DUF222) 5 243 1.3E-11 T 06-07-2017 IPR003870 Domain of unknown function DUF222 CAK77_RS09230 dd68452cbe9f6c435aafef67889c1660 348 SMART SM00507 260 310 1.2E-4 T 06-07-2017 IPR003615 HNH nuclease CAK77_RS17260 3f6817bd98f3db29f6609df3254f912f 214 Pfam PF13578 Methyltransferase domain 73 176 3.4E-14 T 06-07-2017 CAK77_RS17260 3f6817bd98f3db29f6609df3254f912f 214 Gene3D G3DSA:3.40.50.150 37 210 7.6E-35 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS17260 3f6817bd98f3db29f6609df3254f912f 214 SUPERFAMILY SSF53335 40 190 1.81E-27 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS08655 5729c10005b8549fa249b668de1b7ca9 369 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 13 297 1.6E-46 T 06-07-2017 IPR005693 Virulence factor Mce protein CAK77_RS08655 5729c10005b8549fa249b668de1b7ca9 369 Pfam PF02470 MlaD protein 33 107 6.7E-15 T 06-07-2017 IPR003399 Mce/MlaD CAK77_RS16780 f9e26ec658b77bf23856417551a452ff 278 PIRSF PIRSF007580 1 272 7.9E-71 T 06-07-2017 IPR016516 Uncharacterised conserved protein UCP07580 CAK77_RS16780 f9e26ec658b77bf23856417551a452ff 278 Pfam PF10118 Predicted metal-dependent hydrolase 6 254 5.2E-78 T 06-07-2017 IPR016516 Uncharacterised conserved protein UCP07580 CAK77_RS07095 d9c0f1ec0d11e78b9ce1370db07c678d 195 Pfam PF12079 Protein of unknown function (DUF3558) 23 191 2.5E-38 T 06-07-2017 IPR024520 Protein of unknown function DUF3558 CAK77_RS07095 d9c0f1ec0d11e78b9ce1370db07c678d 195 ProDom PD103646 LIPOPROTEIN LPRB MEMBRANE PRECURSOR PALMITATE SIGNAL 41 194 3.0E-45 T 06-07-2017 CAK77_RS11650 f4e5ec1afefbcc5a8211bf65edd02639 110 PIRSF PIRSF018579 1 110 4.3E-47 T 06-07-2017 IPR009709 Protein of unknown function DUF1290 CAK77_RS11650 f4e5ec1afefbcc5a8211bf65edd02639 110 Pfam PF06947 Protein of unknown function (DUF1290) 21 108 2.8E-32 T 06-07-2017 IPR009709 Protein of unknown function DUF1290 CAK77_RS08630 48dc0e6a87ac4e2efe1d0a933b1980ba 289 Pfam PF02405 Permease MlaE 68 278 1.0E-53 T 06-07-2017 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 CAK77_RS13270 7054eb055c9c84803f8fb0147537b672 182 SUPERFAMILY SSF53098 3 179 5.44E-12 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAK77_RS13270 7054eb055c9c84803f8fb0147537b672 182 Gene3D G3DSA:3.30.420.10 2 180 6.3E-12 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAK77_RS09090 990120981e8050e438f50a7f257d5fa9 147 SUPERFAMILY SSF54637 5 128 2.49E-29 T 06-07-2017 IPR029069 HotDog domain CAK77_RS09090 990120981e8050e438f50a7f257d5fa9 147 Gene3D G3DSA:3.10.129.10 3 128 6.9E-35 T 06-07-2017 IPR029069 HotDog domain CAK77_RS09090 990120981e8050e438f50a7f257d5fa9 147 Pfam PF13279 Thioesterase-like superfamily 10 123 1.1E-15 T 06-07-2017 CAK77_RS12125 8f3a7c45342f000035ca06810246cb01 208 SUPERFAMILY SSF48498 93 196 1.93E-6 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAK77_RS12125 8f3a7c45342f000035ca06810246cb01 208 SUPERFAMILY SSF46689 15 85 7.18E-8 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS12125 8f3a7c45342f000035ca06810246cb01 208 Gene3D G3DSA:1.10.357.10 15 198 2.7E-22 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS05525 42efce72be8c805bb08b71d8a385830b 211 Pfam PF14032 PknH-like extracellular domain 42 180 8.5E-7 T 06-07-2017 IPR026954 PknH-like extracellular domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 CAK77_RS17520 ceab0857c189d19007cfe11dd9a0227c 237 Pfam PF14025 Protein of unknown function (DUF4241) 45 203 3.2E-18 T 06-07-2017 IPR025335 Protein of unknown function DUF4241 CAK77_RS02680 6a12f52fa91f30b0a97371509ccdaa95 529 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 24 218 1.0E-13 T 06-07-2017 CAK77_RS02680 6a12f52fa91f30b0a97371509ccdaa95 529 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 22 44 3.7E-7 T 06-07-2017 CAK77_RS02680 6a12f52fa91f30b0a97371509ccdaa95 529 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 147 156 3.7E-7 T 06-07-2017 CAK77_RS02680 6a12f52fa91f30b0a97371509ccdaa95 529 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 188 213 3.7E-7 T 06-07-2017 CAK77_RS02680 6a12f52fa91f30b0a97371509ccdaa95 529 Gene3D G3DSA:3.50.50.60 312 505 5.9E-8 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS02680 6a12f52fa91f30b0a97371509ccdaa95 529 Gene3D G3DSA:3.50.50.60 21 223 6.8E-52 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS02680 6a12f52fa91f30b0a97371509ccdaa95 529 SUPERFAMILY SSF51905 313 430 2.2E-47 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS02680 6a12f52fa91f30b0a97371509ccdaa95 529 SUPERFAMILY SSF51905 23 238 2.2E-47 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAK77_RS18010 d7088c70a44b643f2c70adaa73c81449 292 SUPERFAMILY SSF51197 10 292 1.83E-86 T 06-07-2017 CAK77_RS18010 d7088c70a44b643f2c70adaa73c81449 292 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 12 283 5.7E-62 T 06-07-2017 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 CAK77_RS18010 d7088c70a44b643f2c70adaa73c81449 292 Gene3D G3DSA:3.60.130.10 7 291 3.7E-89 T 06-07-2017 CAK77_RS21345 945c2bbdb506e681296164d97d2e841b 240 Pfam PF10099 Anti-sigma-K factor rskA 69 235 2.8E-23 T 06-07-2017 IPR018764 Anti-sigma K factor RskA GO:0005886|GO:0016021 CAK77_RS05950 19dc602744d046fcebe17c9b42c61dba 260 SUPERFAMILY SSF52096 3 257 2.2E-86 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS05950 19dc602744d046fcebe17c9b42c61dba 260 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 101 121 - T 06-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CAK77_RS05950 19dc602744d046fcebe17c9b42c61dba 260 Pfam PF00378 Enoyl-CoA hydratase/isomerase 16 257 2.4E-80 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAK77_RS05950 19dc602744d046fcebe17c9b42c61dba 260 Gene3D G3DSA:3.90.226.10 3 257 1.6E-97 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS10445 39a3fa2d78fa66471b42d6a3182912fd 414 Pfam PF00487 Fatty acid desaturase 69 338 7.4E-33 T 06-07-2017 IPR005804 Fatty acid desaturase domain GO:0006629 CAK77_RS23485 0aa07a93fc10fa75488bd6e81508baeb 498 Gene3D G3DSA:3.30.70.1450 410 469 8.0E-7 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CAK77_RS23485 0aa07a93fc10fa75488bd6e81508baeb 498 Pfam PF00999 Sodium/hydrogen exchanger family 15 383 3.0E-50 T 06-07-2017 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CAK77_RS23485 0aa07a93fc10fa75488bd6e81508baeb 498 Pfam PF02080 TrkA-C domain 414 473 5.9E-10 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CAK77_RS23485 0aa07a93fc10fa75488bd6e81508baeb 498 SUPERFAMILY SSF116726 408 470 2.62E-10 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CAK77_RS22425 7786b9bb67c531c7bff0a4a2c131a96a 100 Gene3D G3DSA:1.10.287.1060 1 96 9.3E-10 T 06-07-2017 CAK77_RS22425 7786b9bb67c531c7bff0a4a2c131a96a 100 SUPERFAMILY SSF140453 3 95 1.01E-10 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like CAK77_RS22425 7786b9bb67c531c7bff0a4a2c131a96a 100 Pfam PF06013 Proteins of 100 residues with WXG 3 85 6.6E-9 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like CAK77_RS14965 55e3779da29b63dea604d420de345b23 215 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 90 180 1.7E-11 T 06-07-2017 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain CAK77_RS14910 df8f72b868b65dcbc6777ba1c5a4325c 247 Pfam PF11361 Protein of unknown function (DUF3159) 48 231 1.9E-62 T 06-07-2017 IPR016566 Uncharacterised conserved protein UCP010219 CAK77_RS12665 fcf5c902e91c2d476ab959f4909aa5e7 420 Pfam PF00872 Transposase, Mutator family 24 387 5.5E-123 T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 CAK77_RS20795 2098e514a3128001216a1ff48f24919b 388 Pfam PF02470 MlaD protein 42 120 4.4E-12 T 06-07-2017 IPR003399 Mce/MlaD CAK77_RS20795 2098e514a3128001216a1ff48f24919b 388 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 13 306 4.7E-68 T 06-07-2017 IPR005693 Virulence factor Mce protein CAK77_RS22275 8738362086b08f615ad8685498b95863 349 Pfam PF01757 Acyltransferase family 1 328 4.4E-26 T 06-07-2017 IPR002656 Acyltransferase 3 GO:0016747 CAK77_RS19640 20746ddcc315b8a12fc4a7b913570774 327 SUPERFAMILY SSF47240 47 251 5.14E-12 T 06-07-2017 IPR009078 Ferritin-like superfamily CAK77_RS19640 20746ddcc315b8a12fc4a7b913570774 327 Pfam PF11583 P-aminobenzoate N-oxygenase AurF 25 299 3.3E-78 T 06-07-2017 IPR025859 P-aminobenzoate N-oxygenase AurF CAK77_RS09750 13198e9cd3c8c8657b2ef49de1c5fa4b 524 Pfam PF01098 Cell cycle protein 55 409 3.9E-116 T 06-07-2017 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 CAK77_RS09750 13198e9cd3c8c8657b2ef49de1c5fa4b 524 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 56 408 8.2E-115 T 06-07-2017 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 CAK77_RS09750 13198e9cd3c8c8657b2ef49de1c5fa4b 524 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 367 391 - T 06-07-2017 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 CAK77_RS00975 822f64f7b4db65b70d20317c3ca1f26d 187 Pfam PF05257 CHAP domain 73 161 6.9E-9 T 06-07-2017 IPR007921 CHAP domain CAK77_RS16260 80117e168f13c5d368535ad187dcbb6b 181 SUPERFAMILY SSF53335 2 176 5.4E-40 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS16260 80117e168f13c5d368535ad187dcbb6b 181 Pfam PF03602 Conserved hypothetical protein 95 2 177 1.6E-45 T 06-07-2017 CAK77_RS16260 80117e168f13c5d368535ad187dcbb6b 181 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 3 178 6.3E-45 T 06-07-2017 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CAK77_RS16260 80117e168f13c5d368535ad187dcbb6b 181 Gene3D G3DSA:3.40.50.150 2 177 3.5E-50 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS16260 80117e168f13c5d368535ad187dcbb6b 181 PIRSF PIRSF004553 1 181 7.9E-55 T 06-07-2017 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CAK77_RS16260 80117e168f13c5d368535ad187dcbb6b 181 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 116 122 - T 06-07-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CAK77_RS03990 3c3211b1b647d1e671cd6ad712f76c5d 265 Pfam PF11209 Protein of unknown function (DUF2993) 22 250 1.5E-26 T 06-07-2017 IPR021373 Protein of unknown function DUF2993 CAK77_RS23640 e566a8189f536751312efbbc1aa9f0a4 147 Pfam PF05423 Mycobacterium membrane protein 9 147 9.0E-42 T 06-07-2017 IPR008693 Transport accessory protein MmpS CAK77_RS08015 3fe086bf8901f51a7982d40f75b3266c 127 SUPERFAMILY SSF46955 78 124 1.01E-5 T 06-07-2017 IPR009061 Putative DNA-binding domain CAK77_RS08015 3fe086bf8901f51a7982d40f75b3266c 127 Pfam PF12728 Helix-turn-helix domain 78 122 1.5E-9 T 06-07-2017 CAK77_RS16470 ab4ac57c1036dcbb8bf89965585b21a0 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 57 2.0E-15 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS16470 ab4ac57c1036dcbb8bf89965585b21a0 198 Gene3D G3DSA:1.10.357.10 5 190 7.8E-26 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS16470 ab4ac57c1036dcbb8bf89965585b21a0 198 SUPERFAMILY SSF46689 6 70 4.77E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS19145 fd36262fceeca13aff1bd706b83f8746 37 TIGRFAM TIGR03969 mycofactocin: mycofactocin precursor 16 37 1.4E-14 T 06-07-2017 IPR023988 Mycofactocin CAK77_RS00040 11bb984220c6c5d8123675ff5e4385d2 403 Gene3D G3DSA:1.25.10.10 204 357 7.7E-4 T 06-07-2017 IPR011989 Armadillo-like helical CAK77_RS15500 a021cd726e90f576681067192b16b1de 317 SUPERFAMILY SSF56300 5 260 9.27E-27 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAK77_RS15500 a021cd726e90f576681067192b16b1de 317 Pfam PF00149 Calcineurin-like phosphoesterase 8 242 1.2E-15 T 06-07-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 CAK77_RS15500 a021cd726e90f576681067192b16b1de 317 Gene3D G3DSA:3.60.21.10 192 261 2.0E-24 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAK77_RS15500 a021cd726e90f576681067192b16b1de 317 Gene3D G3DSA:3.60.21.10 9 108 2.0E-24 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAK77_RS08660 e58189b3199282af0cd73c1d32d116ff 376 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 155 252 3.9E-8 T 06-07-2017 IPR024516 Mammalian cell entry, C-terminal CAK77_RS08660 e58189b3199282af0cd73c1d32d116ff 376 Pfam PF02470 MlaD protein 37 111 1.1E-12 T 06-07-2017 IPR003399 Mce/MlaD CAK77_RS04760 8ddf15bb4f3cbcf78b4c5cbd996006d3 306 Pfam PF00296 Luciferase-like monooxygenase 2 236 1.4E-50 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS04760 8ddf15bb4f3cbcf78b4c5cbd996006d3 306 SUPERFAMILY SSF51679 1 298 7.95E-63 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS04760 8ddf15bb4f3cbcf78b4c5cbd996006d3 306 Gene3D G3DSA:3.20.20.30 8 280 1.5E-66 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS04440 0853dfc052a7fd663e6ffa9dd590bee0 555 Pfam PF07690 Major Facilitator Superfamily 133 496 2.1E-11 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK77_RS04440 0853dfc052a7fd663e6ffa9dd590bee0 555 SUPERFAMILY SSF103473 126 526 4.88E-17 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK77_RS11165 20adc321ca335f05ff7166b6e87cacf2 402 Pfam PF13367 Protease prsW family 95 282 1.3E-42 T 06-07-2017 IPR026898 Protease PrsW GO:0008233 CAK77_RS05050 33277c1a60fcc6813766a73fa1e593f0 416 Pfam PF02470 MlaD protein 52 125 7.2E-12 T 06-07-2017 IPR003399 Mce/MlaD CAK77_RS00060 efd2304a4ef4b96ebec62b1da1f7aa5b 201 Pfam PF12079 Protein of unknown function (DUF3558) 15 196 3.3E-19 T 06-07-2017 IPR024520 Protein of unknown function DUF3558 CAK77_RS09610 d74256413d6c352cf422015703b97344 223 SUPERFAMILY SSF53335 13 197 3.65E-39 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS09610 d74256413d6c352cf422015703b97344 223 Gene3D G3DSA:3.40.50.150 9 187 1.2E-35 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS09610 d74256413d6c352cf422015703b97344 223 Pfam PF08241 Methyltransferase domain 32 125 9.2E-23 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CAK77_RS10800 f0019c264a788b86adf315c1db94c358 277 Gene3D G3DSA:1.10.3720.10 78 272 8.9E-24 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS10800 f0019c264a788b86adf315c1db94c358 277 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 102 272 6.1E-26 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS10800 f0019c264a788b86adf315c1db94c358 277 SUPERFAMILY SSF161098 79 260 1.96E-32 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS09930 15ccb01fb1e958dcf494a8fe087a91f6 303 Pfam PF12697 Alpha/beta hydrolase family 39 291 3.0E-15 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS09930 15ccb01fb1e958dcf494a8fe087a91f6 303 Gene3D G3DSA:3.40.50.1820 14 301 2.5E-54 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS09930 15ccb01fb1e958dcf494a8fe087a91f6 303 SUPERFAMILY SSF53474 15 300 1.69E-43 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS01325 e01a9f2c94110862a30a587eeafa799b 360 SUPERFAMILY SSF51735 4 111 1.81E-7 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS01325 e01a9f2c94110862a30a587eeafa799b 360 Gene3D G3DSA:3.40.50.720 2 200 3.9E-16 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS01325 e01a9f2c94110862a30a587eeafa799b 360 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 6 69 2.2E-5 T 06-07-2017 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAK77_RS09805 320bf67085aca9bd6d69d80f03e92c9a 97 Pfam PF02325 YGGT family 10 85 1.9E-10 T 06-07-2017 IPR003425 CCB3/YggT GO:0016020 CAK77_RS09935 0e65ff91fc322187b6977c68cc9aec61 206 Gene3D G3DSA:1.10.357.10 15 201 6.4E-24 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAK77_RS09935 0e65ff91fc322187b6977c68cc9aec61 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 1.4E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS09935 0e65ff91fc322187b6977c68cc9aec61 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 1.4E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS09935 0e65ff91fc322187b6977c68cc9aec61 206 SUPERFAMILY SSF46689 11 80 1.31E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAK77_RS09935 0e65ff91fc322187b6977c68cc9aec61 206 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 63 7.1E-13 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAK77_RS12425 63bf42cb2368dd9aae79659ae2ccd860 201 Pfam PF08310 LGFP repeat 85 135 5.4E-7 T 06-07-2017 IPR013207 LGFP CAK77_RS11745 9f464c043d304a5afa901229fe922023 269 Pfam PF14032 PknH-like extracellular domain 82 265 8.7E-33 T 06-07-2017 IPR026954 PknH-like extracellular domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 CAK77_RS11135 a6018a721771e51285324ae50ddfda74 62 Pfam PF06906 Protein of unknown function (DUF1272) 1 54 1.6E-23 T 06-07-2017 IPR010696 Protein of unknown function DUF1272 CAK77_RS04085 58768358fc565baca9e3e979d773338b 382 Pfam PF13556 PucR C-terminal helix-turn-helix domain 317 374 2.1E-22 T 06-07-2017 IPR025736 PucR C-terminal helix-turn-helix domain CAK77_RS17620 8dae1f8d2634cac4cdecd508caa0f8e1 98 Gene3D G3DSA:1.10.10.10 10 83 6.0E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS17620 8dae1f8d2634cac4cdecd508caa0f8e1 98 SUPERFAMILY SSF46767 7 82 3.92E-16 T 06-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CAK77_RS17620 8dae1f8d2634cac4cdecd508caa0f8e1 98 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 12 82 5.4E-18 T 06-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CAK77_RS17330 8d78828a29c91193790edeee2ffb9d4b 68 Pfam PF11662 Protein of unknown function (DUF3263) 4 66 4.4E-27 T 06-07-2017 IPR021678 Protein of unknown function DUF3263 CAK77_RS04675 ac2090c1f8c4317c5a08101c04166d13 338 Pfam PF01636 Phosphotransferase enzyme family 31 269 2.2E-26 T 06-07-2017 IPR002575 Aminoglycoside phosphotransferase CAK77_RS04675 ac2090c1f8c4317c5a08101c04166d13 338 Gene3D G3DSA:3.90.1200.10 125 298 8.4E-27 T 06-07-2017 CAK77_RS04675 ac2090c1f8c4317c5a08101c04166d13 338 SUPERFAMILY SSF56112 10 301 1.74E-47 T 06-07-2017 IPR011009 Protein kinase-like domain CAK77_RS09385 0c338e5b3cdd5f6fbf73885bda67fbe2 105 Pfam PF06013 Proteins of 100 residues with WXG 6 90 1.2E-7 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like CAK77_RS09385 0c338e5b3cdd5f6fbf73885bda67fbe2 105 Gene3D G3DSA:1.10.287.1060 5 97 6.7E-7 T 06-07-2017 CAK77_RS09385 0c338e5b3cdd5f6fbf73885bda67fbe2 105 SUPERFAMILY SSF140453 5 98 2.88E-8 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like CAK77_RS11455 303db7d2adf689e033501e5baea97d70 349 Pfam PF03747 ADP-ribosylglycohydrolase 18 316 8.0E-69 T 06-07-2017 IPR005502 ADP-ribosylation/Crystallin J1 CAK77_RS11455 303db7d2adf689e033501e5baea97d70 349 SUPERFAMILY SSF101478 13 336 2.09E-60 T 06-07-2017 IPR005502 ADP-ribosylation/Crystallin J1 CAK77_RS02485 e89d8ebc13b3716347a9823406a9ab66 194 Pfam PF00482 Type II secretion system (T2SS), protein F 50 173 5.7E-9 T 06-07-2017 IPR018076 Type II secretion system F domain CAK77_RS03390 e54c40af3063477ee55736c2f0eb8640 299 Pfam PF01882 Protein of unknown function DUF58 42 96 3.3E-12 T 06-07-2017 IPR002881 Domain of unknown function DUF58 CAK77_RS20205 f1e410cb4c37031306b89a100d9db3d3 419 Pfam PF02470 MlaD protein 79 148 1.5E-8 T 06-07-2017 IPR003399 Mce/MlaD CAK77_RS19255 7272b39c9f3a871346f6d995dd504b20 247 Pfam PF08223 PaaX-like protein C-terminal domain 90 233 7.5E-13 T 06-07-2017 IPR013225 PaaX-like, C-terminal CAK77_RS19255 7272b39c9f3a871346f6d995dd504b20 247 Pfam PF07848 PaaX-like protein 12 72 9.9E-14 T 06-07-2017 IPR012906 PaaX-like, N-terminal CAK77_RS02090 b3d4aecff6045a8cd64c69f5b2f4b28e 91 Gene3D G3DSA:1.10.10.10 13 64 3.9E-5 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS02090 b3d4aecff6045a8cd64c69f5b2f4b28e 91 SUPERFAMILY SSF46785 5 84 4.73E-6 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS11145 d671157bbc84194d1521283966f0c6e8 164 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 3 146 1.2E-11 T 06-07-2017 IPR019587 Polyketide cyclase/dehydrase CAK77_RS11145 d671157bbc84194d1521283966f0c6e8 164 Gene3D G3DSA:3.30.530.20 3 149 1.8E-11 T 06-07-2017 IPR023393 START-like domain CAK77_RS11145 d671157bbc84194d1521283966f0c6e8 164 SUPERFAMILY SSF55961 3 149 2.64E-17 T 06-07-2017 CAK77_RS12420 3794c64595ed696ed9fd9d81f49a3672 196 SUPERFAMILY SSF54534 91 192 4.12E-22 T 06-07-2017 CAK77_RS12420 3794c64595ed696ed9fd9d81f49a3672 196 Gene3D G3DSA:3.10.50.40 87 194 2.5E-21 T 06-07-2017 CAK77_RS12420 3794c64595ed696ed9fd9d81f49a3672 196 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 109 192 9.2E-13 T 06-07-2017 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 CAK77_RS04240 048fbeb006f9cec7355602594c4197c8 261 Gene3D G3DSA:3.90.226.10 4 203 2.1E-63 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS04240 048fbeb006f9cec7355602594c4197c8 261 Gene3D G3DSA:1.10.12.10 204 260 1.0E-16 T 06-07-2017 IPR014748 Crontonase, C-terminal CAK77_RS04240 048fbeb006f9cec7355602594c4197c8 261 Pfam PF00378 Enoyl-CoA hydratase/isomerase 13 260 1.7E-57 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAK77_RS04240 048fbeb006f9cec7355602594c4197c8 261 SUPERFAMILY SSF52096 6 260 9.59E-79 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS21420 fb02672a4a06ba0e27987dc5fa17b953 155 Pfam PF05423 Mycobacterium membrane protein 13 143 2.2E-15 T 06-07-2017 IPR008693 Transport accessory protein MmpS CAK77_RS23315 5f9b47ef31bdcbd5672561260be67cdf 101 Gene3D G3DSA:3.40.1510.10 18 61 8.0E-4 T 06-07-2017 IPR015111 Hut operon regulatory protein HutP CAK77_RS20870 07faf5aaca3bfad731bfa75a8dac7647 280 Pfam PF00378 Enoyl-CoA hydratase/isomerase 30 279 6.4E-59 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAK77_RS20870 07faf5aaca3bfad731bfa75a8dac7647 280 SUPERFAMILY SSF52096 19 279 3.32E-78 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS20870 07faf5aaca3bfad731bfa75a8dac7647 280 Gene3D G3DSA:3.90.226.10 19 278 1.6E-78 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS11210 27cd7c7f648e4f9f195c829832bb248d 158 Pfam PF16877 Domain of unknown function (DUF5078) 40 156 4.9E-57 T 06-07-2017 IPR031702 Protein of unknown function DUF5078 CAK77_RS20805 aa6458e2b43e9d572f45ce680914bf12 356 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 16 294 4.6E-71 T 06-07-2017 IPR005693 Virulence factor Mce protein CAK77_RS20805 aa6458e2b43e9d572f45ce680914bf12 356 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 179 197 7.5E-13 T 06-07-2017 IPR005693 Virulence factor Mce protein CAK77_RS20805 aa6458e2b43e9d572f45ce680914bf12 356 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 299 318 7.5E-13 T 06-07-2017 IPR005693 Virulence factor Mce protein CAK77_RS20805 aa6458e2b43e9d572f45ce680914bf12 356 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 32 52 7.5E-13 T 06-07-2017 IPR005693 Virulence factor Mce protein CAK77_RS20805 aa6458e2b43e9d572f45ce680914bf12 356 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 95 111 7.5E-13 T 06-07-2017 IPR005693 Virulence factor Mce protein CAK77_RS20805 aa6458e2b43e9d572f45ce680914bf12 356 Pfam PF02470 MlaD protein 43 117 1.4E-15 T 06-07-2017 IPR003399 Mce/MlaD CAK77_RS17990 5ffdc3584d27e226c997763c98bb2956 293 Pfam PF04480 Protein of unknown function (DUF559) 222 288 2.9E-5 T 06-07-2017 IPR007569 Domain of unknown function DUF559 CAK77_RS17990 5ffdc3584d27e226c997763c98bb2956 293 SUPERFAMILY SSF52980 178 288 1.39E-7 T 06-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CAK77_RS17990 5ffdc3584d27e226c997763c98bb2956 293 Pfam PF13338 Transcriptional regulator, AbiEi antitoxin 25 94 1.2E-6 T 06-07-2017 IPR025159 Transcriptional regulator, AbiEi antitoxin CAK77_RS22725 74fbaaca777b504870ff03f51014653d 352 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 29 301 6.5E-47 T 06-07-2017 IPR005693 Virulence factor Mce protein CAK77_RS22725 74fbaaca777b504870ff03f51014653d 352 Pfam PF02470 MlaD protein 53 126 1.4E-16 T 06-07-2017 IPR003399 Mce/MlaD CAK77_RS05770 316f651bee89add09000663a509c8218 255 SUPERFAMILY SSF53955 76 252 1.22E-34 T 06-07-2017 IPR023346 Lysozyme-like domain CAK77_RS05770 316f651bee89add09000663a509c8218 255 Gene3D G3DSA:1.10.530.10 166 235 1.1E-8 T 06-07-2017 CAK77_RS05770 316f651bee89add09000663a509c8218 255 Gene3D G3DSA:1.10.530.10 100 126 1.1E-8 T 06-07-2017 CAK77_RS05770 316f651bee89add09000663a509c8218 255 Pfam PF13406 Transglycosylase SLT domain 172 216 5.6E-6 T 06-07-2017 IPR031304 Transglycosylase SLT domain 2 CAK77_RS19960 776d422b394f2633ef2da070f5fdb662 252 Pfam PF13649 Methyltransferase domain 77 168 3.8E-13 T 06-07-2017 CAK77_RS19960 776d422b394f2633ef2da070f5fdb662 252 Gene3D G3DSA:3.40.50.150 60 223 3.0E-16 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS19960 776d422b394f2633ef2da070f5fdb662 252 SUPERFAMILY SSF53335 60 225 2.15E-21 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAK77_RS19660 bd588a9e472a11c7954ededbda196cbc 146 SUPERFAMILY SSF54637 5 143 9.07E-36 T 06-07-2017 IPR029069 HotDog domain CAK77_RS19660 bd588a9e472a11c7954ededbda196cbc 146 Gene3D G3DSA:3.10.129.10 8 146 4.7E-51 T 06-07-2017 IPR029069 HotDog domain CAK77_RS19660 bd588a9e472a11c7954ededbda196cbc 146 Pfam PF03061 Thioesterase superfamily 58 136 3.0E-14 T 06-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 CAK77_RS19660 bd588a9e472a11c7954ededbda196cbc 146 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 27 143 2.9E-25 T 06-07-2017 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-75105 CAK77_RS20750 45ecb13759c7c8142cd2e311e767e3f1 171 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 29 136 2.1E-13 T 06-07-2017 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CAK77_RS20750 45ecb13759c7c8142cd2e311e767e3f1 171 SUPERFAMILY SSF55961 7 167 1.65E-32 T 06-07-2017 CAK77_RS20750 45ecb13759c7c8142cd2e311e767e3f1 171 Gene3D G3DSA:3.30.530.20 3 169 1.2E-43 T 06-07-2017 IPR023393 START-like domain CAK77_RS20700 63245fbaef286fae2f8e9e9f8bafdd6f 92 Pfam PF16936 Putative holin 14 91 1.3E-35 T 06-07-2017 IPR031614 Putative holin CAK77_RS19525 43a7b104eaabd0f5f3efb5e2da1ea99e 374 Gene3D G3DSA:2.40.180.10 29 361 1.3E-33 T 06-07-2017 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAK77_RS19525 43a7b104eaabd0f5f3efb5e2da1ea99e 374 SUPERFAMILY SSF56634 46 360 1.24E-45 T 06-07-2017 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAK77_RS11945 d353edfd9c29041d9b21611bd489b92d 176 Pfam PF14026 Protein of unknown function (DUF4242) 96 169 2.6E-20 T 06-07-2017 IPR025336 Protein of unknown function DUF4242 CAK77_RS07770 e1b3c9d8e3880563f6cdc01e8f530bd3 611 Pfam PF13520 Amino acid permease 54 432 7.2E-21 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CAK77_RS01245 5007d4a0faf2dc3c494a254172d97f5a 307 SUPERFAMILY SSF56563 37 293 1.11E-6 T 06-07-2017 CAK77_RS22710 8a405fd9592231721991d49ccc8cfd4c 417 Pfam PF02470 MlaD protein 52 126 8.0E-10 T 06-07-2017 IPR003399 Mce/MlaD CAK77_RS07020 f2b60659c0807a176dd2e9c770062942 190 Pfam PF14041 LppP/LprE lipoprotein 101 180 9.1E-12 T 06-07-2017 IPR025971 LppP/LprE lipoprotein CAK77_RS07020 f2b60659c0807a176dd2e9c770062942 190 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 65 185 2.0E-35 T 06-07-2017 CAK77_RS20380 af1572eaebe7db1d495886dbda7c7505 171 Pfam PF10698 Protein of unknown function (DUF2505) 8 167 4.3E-43 T 06-07-2017 IPR019639 Protein of unknown function DUF2505 CAK77_RS05030 8ed907d23d82b23a837b332f7b6eba7d 132 Pfam PF14248 Domain of unknown function (DUF4345) 15 118 8.2E-11 T 06-07-2017 IPR025597 Protein of unknown function DUF4345 CAK77_RS09785 758d7deda7d80e4c9a94a1de97849710 213 Pfam PF04472 Protein of unknown function (DUF552) 125 196 3.3E-24 T 06-07-2017 IPR007561 Cell division protein SepF/SepF-related GO:0090529 CAK77_RS09785 758d7deda7d80e4c9a94a1de97849710 213 Hamap MF_01197 Cell division protein SepF [sepF]. 1 204 21.52 T 06-07-2017 IPR023052 Cell division protein SepF GO:0090529 CAK77_RS17985 1abc8a3e56c05a967144bf72a5baaea5 227 SUPERFAMILY SSF56801 14 223 6.28E-14 T 06-07-2017 CAK77_RS17985 1abc8a3e56c05a967144bf72a5baaea5 227 Gene3D G3DSA:3.40.50.980 31 89 5.9E-5 T 06-07-2017 CAK77_RS17985 1abc8a3e56c05a967144bf72a5baaea5 227 TIGRFAM TIGR03089 TIGR03089: TIGR03089 family protein 15 223 3.7E-67 T 06-07-2017 IPR017523 Conserved hypothetical protein CHP03089 CAK77_RS24060 d817466c79bf9c75f93f5830ed5d636e 105 SUPERFAMILY SSF46785 21 98 9.7E-7 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS24060 d817466c79bf9c75f93f5830ed5d636e 105 Gene3D G3DSA:1.10.10.10 22 100 2.1E-5 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS01940 4d235f52af39957226566b44e1cb5f0d 413 Pfam PF00999 Sodium/hydrogen exchanger family 12 364 5.5E-31 T 06-07-2017 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CAK77_RS07565 6ceec6d6738e5c5f3bd289950f13f203 297 SUPERFAMILY SSF161098 21 281 2.9E-49 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS07565 6ceec6d6738e5c5f3bd289950f13f203 297 TIGRFAM TIGR03226 PhnU: 2-aminoethylphosphonate ABC transporter, permease protein 15 285 6.8E-87 T 06-07-2017 IPR017636 2-aminoethylphosphonate ABC transporter system, permease protein phnU GO:0016020|GO:0033223 CAK77_RS07565 6ceec6d6738e5c5f3bd289950f13f203 297 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 90 285 6.1E-18 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS07565 6ceec6d6738e5c5f3bd289950f13f203 297 Gene3D G3DSA:1.10.3720.10 20 285 3.8E-45 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAK77_RS05085 c9c705558b9687fe321c90d5f743b991 224 Pfam PF02405 Permease MlaE 109 214 2.0E-22 T 06-07-2017 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 CAK77_RS18690 56804ebaeec53c2530b0553eef2637ba 101 SUPERFAMILY SSF140453 5 98 1.57E-7 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like CAK77_RS18690 56804ebaeec53c2530b0553eef2637ba 101 Gene3D G3DSA:1.10.287.1060 1 99 8.4E-7 T 06-07-2017 CAK77_RS18690 56804ebaeec53c2530b0553eef2637ba 101 Pfam PF10824 Excreted virulence factor EspC, type VII ESX diderm 5 96 7.0E-10 T 06-07-2017 IPR022536 ESX-1 secretion-associated protein EspC CAK77_RS23110 c7e399fbd802bbdf280096df4d7a6d7c 455 Gene3D G3DSA:3.90.1300.10 2 442 1.0E-116 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAK77_RS23110 c7e399fbd802bbdf280096df4d7a6d7c 455 ProSitePatterns PS00571 Amidases signature. 130 161 - T 06-07-2017 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 CAK77_RS23110 c7e399fbd802bbdf280096df4d7a6d7c 455 Pfam PF01425 Amidase 2 428 5.5E-98 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAK77_RS23110 c7e399fbd802bbdf280096df4d7a6d7c 455 SUPERFAMILY SSF75304 2 445 8.37E-118 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAK77_RS10840 b0ccb49dc7d2ae86140a7638b63b7b5a 332 TIGRFAM TIGR03923 T7SS_EccE: type VII secretion protein EccE 19 305 4.6E-69 T 06-07-2017 IPR021368 Type VII secretion system protein EccE CAK77_RS10840 b0ccb49dc7d2ae86140a7638b63b7b5a 332 Pfam PF11203 Putative type VII ESX secretion system translocon, EccE 148 202 8.8E-10 T 06-07-2017 IPR021368 Type VII secretion system protein EccE CAK77_RS02500 db204451044754faad4e404c263c8562 129 Pfam PF13400 Putative Flp pilus-assembly TadE/G-like 18 64 3.8E-9 T 06-07-2017 IPR028087 Putative Flp pilus-assembly TadG-like, N-terminal CAK77_RS02500 db204451044754faad4e404c263c8562 129 TIGRFAM TIGR03816 tadE_like_DECH: helicase/secretion neighborhood TadE-like protein 16 124 9.7E-29 T 06-07-2017 IPR021202 Helicase/secretion neighbourhood TadE-like protein CAK77_RS14385 617504e0c2d3f1ef1652bd8b604768f1 193 Gene3D G3DSA:3.40.630.30 31 173 2.0E-20 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS14385 617504e0c2d3f1ef1652bd8b604768f1 193 SUPERFAMILY SSF55729 32 171 1.12E-19 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAK77_RS14385 617504e0c2d3f1ef1652bd8b604768f1 193 Pfam PF00583 Acetyltransferase (GNAT) family 97 170 3.2E-8 T 06-07-2017 IPR000182 GNAT domain GO:0008080 CAK77_RS22540 75e98d91cbce3c46ef1e6ac316678039 923 Gene3D G3DSA:1.20.1640.10 155 339 7.5E-27 T 06-07-2017 CAK77_RS22540 75e98d91cbce3c46ef1e6ac316678039 923 Gene3D G3DSA:1.20.1640.10 485 704 9.9E-34 T 06-07-2017 CAK77_RS22540 75e98d91cbce3c46ef1e6ac316678039 923 SUPERFAMILY SSF82866 481 699 2.09E-27 T 06-07-2017 CAK77_RS22540 75e98d91cbce3c46ef1e6ac316678039 923 Pfam PF03176 MMPL family 149 368 6.0E-39 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 CAK77_RS22540 75e98d91cbce3c46ef1e6ac316678039 923 Pfam PF03176 MMPL family 439 699 2.5E-39 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 CAK77_RS22540 75e98d91cbce3c46ef1e6ac316678039 923 SUPERFAMILY SSF82866 156 336 2.75E-25 T 06-07-2017 CAK77_RS23365 bdb13a6248d5e62c6e90a5d5c32fdc06 82 SUPERFAMILY SSF160582 9 76 1.96E-30 T 06-07-2017 CAK77_RS23365 bdb13a6248d5e62c6e90a5d5c32fdc06 82 Gene3D G3DSA:3.90.820.10 17 76 5.4E-31 T 06-07-2017 CAK77_RS23365 bdb13a6248d5e62c6e90a5d5c32fdc06 82 Pfam PF03621 MbtH-like protein 10 60 3.7E-28 T 06-07-2017 IPR005153 MbtH-like protein CAK77_RS23365 bdb13a6248d5e62c6e90a5d5c32fdc06 82 SMART SM00923 10 60 2.4E-34 T 06-07-2017 IPR005153 MbtH-like protein CAK77_RS18555 b949ff4075dfaabf67b6262ca744ed06 109 Pfam PF14230 Domain of unknown function (DUF4333) 13 91 1.1E-17 T 06-07-2017 IPR025637 Domain of unknown function DUF4333 CAK77_RS06090 7db0f6d8ca26174c60c9d91abf43ebe0 66 Pfam PF13459 4Fe-4S single cluster domain 5 63 1.0E-11 T 06-07-2017 CAK77_RS06090 7db0f6d8ca26174c60c9d91abf43ebe0 66 SUPERFAMILY SSF54862 4 64 2.23E-10 T 06-07-2017 CAK77_RS06090 7db0f6d8ca26174c60c9d91abf43ebe0 66 Gene3D G3DSA:3.30.70.20 3 65 3.2E-14 T 06-07-2017 CAK77_RS00305 49e2a565a6fdcefb1cb27f135d64b318 141 Pfam PF10756 Bacterial PH domain 63 139 5.0E-13 T 06-07-2017 IPR019692 Protein of unknown function DUF2581 CAK77_RS20200 6d5e06d966e3c590e22bbe71a80ce7eb 334 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 23 293 2.6E-43 T 06-07-2017 IPR005693 Virulence factor Mce protein CAK77_RS20200 6d5e06d966e3c590e22bbe71a80ce7eb 334 Pfam PF02470 MlaD protein 47 120 1.0E-11 T 06-07-2017 IPR003399 Mce/MlaD CAK77_RS09360 40277b902172599327a7028adedfde79 136 Pfam PF07681 DoxX 18 92 1.6E-11 T 06-07-2017 IPR032808 DoxX family CAK77_RS05040 3b8fab5aadad418ad335b33efcecc8b5 272 Pfam PF12151 Mannan-binding protein 33 69 1.4E-12 T 06-07-2017 IPR021992 Mannan-binding protein CAK77_RS05040 3b8fab5aadad418ad335b33efcecc8b5 272 Pfam PF11738 Protein of unknown function (DUF3298) 160 259 2.4E-9 T 06-07-2017 IPR021729 Domain of unknown function DUF3298 CAK77_RS06615 3c4eecf4350ad2e00b9680bed0f9db8c 197 Pfam PF05901 Excalibur calcium-binding domain 30 65 4.6E-14 T 06-07-2017 IPR008613 Excalibur calcium-binding domain CAK77_RS06615 3c4eecf4350ad2e00b9680bed0f9db8c 197 SMART SM00894 29 65 3.4E-20 T 06-07-2017 IPR008613 Excalibur calcium-binding domain CAK77_RS02615 924c8e7f2737167574cacfadc64f154a 187 Pfam PF11611 Domain of unknown function (DUF4352) 56 181 1.3E-17 T 06-07-2017 IPR029051 Domain of unknown function DUF4352 CAK77_RS02615 924c8e7f2737167574cacfadc64f154a 187 Gene3D G3DSA:2.60.40.1240 56 166 2.3E-8 T 06-07-2017 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain CAK77_RS02520 5dddd0e62c41f2bb3a4b9ab70969a580 285 Pfam PF10118 Predicted metal-dependent hydrolase 13 260 1.0E-76 T 06-07-2017 IPR016516 Uncharacterised conserved protein UCP07580 CAK77_RS02520 5dddd0e62c41f2bb3a4b9ab70969a580 285 PIRSF PIRSF007580 1 279 2.6E-74 T 06-07-2017 IPR016516 Uncharacterised conserved protein UCP07580 CAK77_RS02540 cddfa9d3adac7bf791199103b1e19e20 367 SUPERFAMILY SSF51395 1 356 3.38E-104 T 06-07-2017 CAK77_RS02540 cddfa9d3adac7bf791199103b1e19e20 367 Gene3D G3DSA:3.20.20.70 1 354 9.1E-117 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK77_RS02540 cddfa9d3adac7bf791199103b1e19e20 367 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 4 350 8.0E-61 T 06-07-2017 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 CAK77_RS01635 978ef8581d84135712323d3018ea343f 236 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 7 201 2.5E-37 T 06-07-2017 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 CAK77_RS01635 978ef8581d84135712323d3018ea343f 236 SUPERFAMILY SSF52317 18 212 1.01E-21 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAK77_RS01635 978ef8581d84135712323d3018ea343f 236 Gene3D G3DSA:3.40.50.880 7 211 4.6E-21 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAK77_RS01930 2228005f31e620f4f0dbac11afe8da29 241 Gene3D G3DSA:1.10.10.10 95 180 1.7E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS01930 2228005f31e620f4f0dbac11afe8da29 241 SUPERFAMILY SSF46785 90 189 3.53E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAK77_RS01930 2228005f31e620f4f0dbac11afe8da29 241 Pfam PF03551 Transcriptional regulator PadR-like family 106 175 1.8E-20 T 06-07-2017 IPR005149 Transcription regulator PadR, N-terminal CAK77_RS13785 6ce401761cbbbb5c78e14a9780e7f635 263 Pfam PF02544 3-oxo-5-alpha-steroid 4-dehydrogenase 112 262 9.3E-36 T 06-07-2017 IPR001104 3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal GO:0005737|GO:0006629|GO:0016021|GO:0016627 CAK77_RS13785 6ce401761cbbbb5c78e14a9780e7f635 263 PIRSF PIRSF015596 1 263 6.1E-78 T 06-07-2017 IPR016636 3-oxo-5-alpha-steroid 4-dehydrogenase GO:0003865|GO:0008202|GO:0016020|GO:0055114 KEGG: 00140+1.3.1.22|KEGG: 00905+1.3.1.22|MetaCyc: PWY-6032|MetaCyc: PWY-7455|Reactome: R-HSA-193048 CAK77_RS23480 b9f880ba6e6aa59b0cd3a928da31a73d 556 Pfam PF01566 Natural resistance-associated macrophage protein 54 407 6.3E-75 T 06-07-2017 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CAK77_RS12995 72db0763b153307b9789d9a1629728d9 118 Pfam PF05154 TM2 domain 46 99 4.4E-10 T 06-07-2017 IPR007829 TM2 domain CAK77_RS04970 5961bc59f647abafce7d5fbbd719ca89 231 Pfam PF07751 Abi-like protein 16 185 3.2E-6 T 06-07-2017 IPR011664 Abortive infection system protein AbiD/AbiF-like CAK77_RS14605 0eb1802b7a13c99c7383a9428d0ae892 468 Gene3D G3DSA:3.20.20.140 78 395 1.1E-86 T 06-07-2017 CAK77_RS14605 0eb1802b7a13c99c7383a9428d0ae892 468 Pfam PF01979 Amidohydrolase family 69 409 6.7E-43 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAK77_RS14605 0eb1802b7a13c99c7383a9428d0ae892 468 Gene3D G3DSA:2.30.40.10 34 77 4.0E-4 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK77_RS14605 0eb1802b7a13c99c7383a9428d0ae892 468 SUPERFAMILY SSF51556 72 397 4.13E-69 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAK77_RS14605 0eb1802b7a13c99c7383a9428d0ae892 468 SUPERFAMILY SSF51338 30 85 1.44E-7 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAK77_RS05915 0a61be394437c38157c42fd0a267a115 204 Pfam PF08310 LGFP repeat 105 155 1.9E-12 T 06-07-2017 IPR013207 LGFP CAK77_RS24005 41af74059d399c8159ee9721e08f8513 458 SUPERFAMILY SSF103473 3 184 1.83E-40 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK77_RS24005 41af74059d399c8159ee9721e08f8513 458 SUPERFAMILY SSF103473 240 433 1.83E-40 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAK77_RS24005 41af74059d399c8159ee9721e08f8513 458 Gene3D G3DSA:1.20.1250.20 3 182 8.8E-20 T 06-07-2017 CAK77_RS24005 41af74059d399c8159ee9721e08f8513 458 Gene3D G3DSA:1.20.1250.20 255 433 1.1E-9 T 06-07-2017 CAK77_RS24005 41af74059d399c8159ee9721e08f8513 458 Pfam PF07690 Major Facilitator Superfamily 3 398 5.1E-37 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAK77_RS22255 94fdc6998f90df47d6e5b9381740c1e4 558 Pfam PF00884 Sulfatase 46 382 2.9E-44 T 06-07-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 CAK77_RS22255 94fdc6998f90df47d6e5b9381740c1e4 558 Gene3D G3DSA:3.40.720.10 46 383 4.6E-65 T 06-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CAK77_RS22255 94fdc6998f90df47d6e5b9381740c1e4 558 SUPERFAMILY SSF53649 459 497 6.94E-71 T 06-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CAK77_RS22255 94fdc6998f90df47d6e5b9381740c1e4 558 SUPERFAMILY SSF53649 45 427 6.94E-71 T 06-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CAK77_RS21245 0caaa3aec7346d3f448341d733efbe3f 136 Gene3D G3DSA:2.30.110.10 11 133 3.2E-26 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS21245 0caaa3aec7346d3f448341d733efbe3f 136 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 13 94 3.5E-15 T 06-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAK77_RS21245 0caaa3aec7346d3f448341d733efbe3f 136 SUPERFAMILY SSF50475 5 133 3.74E-26 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAK77_RS21245 0caaa3aec7346d3f448341d733efbe3f 136 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 14 133 1.8E-32 T 06-07-2017 IPR019920 F420-binding domain, putative CAK77_RS20410 0ba8ae2e1629a480ab7f670e98f2b53f 145 Pfam PF05481 Mycobacterium 19 kDa lipoprotein antigen 2 144 1.1E-37 T 06-07-2017 IPR008691 19kDa lipoprotein antigen GO:0016020 CAK77_RS13210 8e680cddc8a4d5b86073a1922872b971 252 SUPERFAMILY SSF81324 137 251 2.2E-5 T 06-07-2017 CAK77_RS22965 845d9de6aa4a422533d5d16e2578bf3f 211 Gene3D G3DSA:3.40.50.1820 3 210 4.7E-22 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS22965 845d9de6aa4a422533d5d16e2578bf3f 211 SUPERFAMILY SSF53474 2 210 2.13E-24 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS22965 845d9de6aa4a422533d5d16e2578bf3f 211 Pfam PF12146 Serine aminopeptidase, S33 3 194 7.3E-10 T 06-07-2017 IPR022742 Serine aminopeptidase, S33 CAK77_RS14190 2c62a4c37658d0be6ff533681429d3fc 256 Pfam PF01965 DJ-1/PfpI family 2 163 1.9E-21 T 06-07-2017 IPR002818 DJ-1/PfpI CAK77_RS14190 2c62a4c37658d0be6ff533681429d3fc 256 Gene3D G3DSA:3.40.50.880 1 211 3.1E-62 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAK77_RS14190 2c62a4c37658d0be6ff533681429d3fc 256 SUPERFAMILY SSF52317 1 189 2.19E-42 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAK77_RS12745 977dcbf5b51172e6ca9c0f97c26c9a78 257 Pfam PF09900 Predicted membrane protein (DUF2127) 75 220 7.9E-45 T 06-07-2017 IPR021125 Protein of unknown function DUF2127 CAK77_RS16355 cc2d68c74e33b2baa745302cf716095f 180 Pfam PF12028 Protein of unknown function (DUF3515) 21 171 2.0E-48 T 06-07-2017 IPR021903 Protein of unknown function DUF3515 CAK77_RS08315 7ee0cdeaa85f60d8e878d3559e2ff577 122 SUPERFAMILY SSF49503 29 106 8.7E-6 T 06-07-2017 IPR008972 Cupredoxin CAK77_RS07730 a02b4d623faaf4fa913fede3c684f746 508 SUPERFAMILY SSF52540 39 399 5.82E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS07730 a02b4d623faaf4fa913fede3c684f746 508 Gene3D G3DSA:3.40.50.300 233 398 2.9E-54 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS07730 a02b4d623faaf4fa913fede3c684f746 508 Gene3D G3DSA:3.40.50.300 42 115 2.9E-54 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAK77_RS07730 a02b4d623faaf4fa913fede3c684f746 508 Pfam PF05872 Bacterial protein of unknown function (DUF853) 39 471 5.6E-185 T 06-07-2017 IPR033186 Helicase HerA-like C-terminal CAK77_RS14055 fab39e0dd156e1ea62187e1bd252337b 223 Pfam PF00753 Metallo-beta-lactamase superfamily 11 203 6.8E-27 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK77_RS14055 fab39e0dd156e1ea62187e1bd252337b 223 SUPERFAMILY SSF56281 4 220 1.97E-48 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK77_RS14055 fab39e0dd156e1ea62187e1bd252337b 223 Gene3D G3DSA:3.60.15.10 8 220 1.3E-50 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK77_RS14055 fab39e0dd156e1ea62187e1bd252337b 223 SMART SM00849 12 203 1.7E-37 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAK77_RS12140 8709e3772ad7969add18df1994ad8d49 205 Pfam PF07077 Protein of unknown function (DUF1345) 28 194 7.3E-51 T 06-07-2017 IPR009781 Protein of unknown function DUF1345 CAK77_RS01895 4b0ba6cb358797a014e556b77f8df74d 384 Gene3D G3DSA:1.10.287.1060 11 93 9.0E-5 T 06-07-2017 CAK77_RS01895 4b0ba6cb358797a014e556b77f8df74d 384 SUPERFAMILY SSF140453 11 93 1.44E-5 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like CAK77_RS09790 2d6945ad68bd98e5ad02d68ba3f759bf 248 Pfam PF05988 Bacterial protein of unknown function (DUF899) 1 221 6.3E-77 T 06-07-2017 IPR010296 Protein of unknown function DUF899, thioredoxin-like CAK77_RS09215 4369d0a7eda396935151c6b1b7753034 240 Pfam PF02591 C4-type zinc ribbon domain 203 237 9.9E-11 T 06-07-2017 IPR003743 C4-type zinc ribbon domain CAK77_RS20190 c47a9ac8385270f295b6a76c92bdf458 362 Pfam PF02470 MlaD protein 58 123 3.0E-9 T 06-07-2017 IPR003399 Mce/MlaD CAK77_RS03510 2c7d641acd860141762345bcba90c832 323 Pfam PF00892 EamA-like transporter family 146 290 1.3E-16 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAK77_RS03510 2c7d641acd860141762345bcba90c832 323 Pfam PF00892 EamA-like transporter family 7 131 1.6E-15 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAK77_RS03510 2c7d641acd860141762345bcba90c832 323 SUPERFAMILY SSF103481 217 291 8.11E-11 T 06-07-2017 CAK77_RS03510 2c7d641acd860141762345bcba90c832 323 SUPERFAMILY SSF103481 40 133 7.72E-13 T 06-07-2017 CAK77_RS22870 d9cf88f820f90d38fe88f06f3ef49e81 395 Pfam PF02470 MlaD protein 44 118 1.7E-12 T 06-07-2017 IPR003399 Mce/MlaD CAK77_RS24200 7218de9d6929c0cebffe6c5deea1cd96 446 SUPERFAMILY SSF48208 27 81 3.35E-51 T 06-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 CAK77_RS24200 7218de9d6929c0cebffe6c5deea1cd96 446 SUPERFAMILY SSF48208 108 188 3.35E-51 T 06-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 CAK77_RS24200 7218de9d6929c0cebffe6c5deea1cd96 446 SUPERFAMILY SSF48208 239 445 3.35E-51 T 06-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 CAK77_RS15645 df39a5091edfbb6e8499c47cfb571a74 227 Pfam PF11139 Sap, sulfolipid-1-addressing protein 5 221 1.5E-50 T 06-07-2017 IPR021315 Glycolipid exporter Gap/Sap CAK77_RS09885 4435293b811e6858e0256128d0c74edc 152 Pfam PF05423 Mycobacterium membrane protein 18 152 1.6E-34 T 06-07-2017 IPR008693 Transport accessory protein MmpS CAK77_RS17095 1b5770af964d71f749ded25451c1bae0 239 Pfam PF13490 Putative zinc-finger 3 37 5.3E-9 T 06-07-2017 IPR027383 Putative zinc-finger CAK77_RS17095 1b5770af964d71f749ded25451c1bae0 239 Pfam PF10039 Predicted integral membrane protein (DUF2275) 60 211 2.8E-13 T 06-07-2017 IPR018734 Domain of unknown function DUF2275 CAK77_RS23350 afb08c090be75c56216e9c74abb9c8b2 230 Pfam PF04191 Phospholipid methyltransferase 117 209 3.3E-13 T 06-07-2017 IPR007318 Phospholipid methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825|Reactome: R-HSA-1483191 CAK77_RS07715 9c8abd454f5d563da7cd5fbfc30bcbed 295 Pfam PF05103 DivIVA protein 10 126 4.6E-9 T 06-07-2017 IPR007793 DivIVA family CAK77_RS01775 c409670ece69e0396e2a91e4b188dab5 212 Pfam PF14032 PknH-like extracellular domain 27 210 3.0E-34 T 06-07-2017 IPR026954 PknH-like extracellular domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 CAK77_RS17775 646c3ae392dd4ab4cf72dee804ff07fc 407 Pfam PF00487 Fatty acid desaturase 69 340 4.7E-32 T 06-07-2017 IPR005804 Fatty acid desaturase domain GO:0006629 CAK77_RS08480 832323c1fa837bbe48b52911ad79b60f 102 PIRSF PIRSF006909 1 101 1.6E-57 T 06-07-2017 IPR014447 Uncharacterised conserved protein UCP006909 CAK77_RS17490 77f461a3ac051debfe6052c0a2b6d69e 148 SUPERFAMILY SSF81923 5 139 3.04E-21 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 CAK77_RS17490 77f461a3ac051debfe6052c0a2b6d69e 148 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 16 63 7.7E-14 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 CAK77_RS17490 77f461a3ac051debfe6052c0a2b6d69e 148 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 93 131 0.029 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 CAK77_RS17490 77f461a3ac051debfe6052c0a2b6d69e 148 Gene3D G3DSA:1.10.1780.10 1 140 2.8E-30 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 CAK77_RS07300 2972560b925fb57ee86480c3a6388fdb 138 Pfam PF10739 Protein of unknown function (DUF2550) 6 130 7.7E-41 T 06-07-2017 IPR019675 Protein of unknown function DUF2550 CAK77_RS03815 19f70f2ef97ffce43697d6a3eb86deab 77 Pfam PF13490 Putative zinc-finger 6 39 2.6E-10 T 06-07-2017 IPR027383 Putative zinc-finger CAK77_RS03660 294153812eb59cda2d6f22c7830f009b 214 Pfam PF02517 CAAX protease self-immunity 97 190 4.2E-17 T 06-07-2017 IPR003675 CAAX amino terminal protease GO:0016020 CAK77_RS03660 294153812eb59cda2d6f22c7830f009b 214 PIRSF PIRSF026622 2 204 1.3E-33 T 06-07-2017 IPR015837 Uncharacterised conserved protein UCP026622, CAAX protease-type CAK77_RS09240 14e96240ab3daa717783bc39a431c26d 409 Pfam PF01882 Protein of unknown function DUF58 182 265 1.6E-18 T 06-07-2017 IPR002881 Domain of unknown function DUF58 CAK77_RS13960 0a2c7cba91cd6be361dc8e2a0c0c574d 280 Pfam PF11296 Protein of unknown function (DUF3097) 4 277 1.3E-124 T 06-07-2017 IPR021447 Protein of unknown function DUF3097 CAK77_RS11890 48a15e94bd16b1cd637773604f0cbfd1 126 Pfam PF14248 Domain of unknown function (DUF4345) 5 117 7.8E-28 T 06-07-2017 IPR025597 Protein of unknown function DUF4345 CAK77_RS11655 8d2de54b52efe84a753fc86eb3971072 273 Pfam PF05949 Bacterial protein of unknown function (DUF881) 132 270 2.5E-35 T 06-07-2017 IPR010273 Protein of unknown function DUF881 CAK77_RS09255 c0d8763c9a577070e10d6fdadf4a89f9 305 Pfam PF13559 Domain of unknown function (DUF4129) 225 292 5.6E-10 T 06-07-2017 IPR025403 Domain of unknown function DUF4129 CAK77_RS04175 65616dc23ab871f17891b13b88de609c 291 Pfam PF00892 EamA-like transporter family 153 284 1.2E-12 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAK77_RS04175 65616dc23ab871f17891b13b88de609c 291 Pfam PF00892 EamA-like transporter family 11 141 1.5E-8 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAK77_RS04175 65616dc23ab871f17891b13b88de609c 291 SUPERFAMILY SSF103481 195 289 3.14E-9 T 06-07-2017 CAK77_RS04175 65616dc23ab871f17891b13b88de609c 291 SUPERFAMILY SSF103481 49 147 1.14E-5 T 06-07-2017 CAK77_RS21955 16c7958aefe5dd8fd5f62f71e4eecd50 43 Gene3D G3DSA:3.40.190.10 10 41 1.3E-6 T 06-07-2017 CAK77_RS24225 b16a69023273be4af34a6ad626759c1c 321 Pfam PF10738 Probable lipoprotein LpqN 84 251 1.8E-57 T 06-07-2017 IPR019674 Lipoprotein LpqT, predicted CAK77_RS01945 53952e608c616a7b679201e61608c46e 280 Pfam PF06271 RDD family 17 144 2.9E-17 T 06-07-2017 IPR010432 RDD CAK77_RS20080 d92c33f5641ff8cdfbd7f0e3adf5725f 147 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 41 144 1.5E-24 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CAK77_RS20080 d92c33f5641ff8cdfbd7f0e3adf5725f 147 Pfam PF04075 Domain of unknown function (DUF385) 29 145 1.1E-29 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CAK77_RS17905 ecc87da8c395bb68a32662ba22b1e92c 491 PIRSF PIRSF006060 8 486 5.6E-86 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CAK77_RS17905 ecc87da8c395bb68a32662ba22b1e92c 491 Pfam PF13520 Amino acid permease 30 455 7.3E-52 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CAK77_RS22610 19a5a0a93ef4975049bb8bafa95f7bbb 209 Pfam PF03713 Domain of unknown function (DUF305) 64 207 1.0E-48 T 06-07-2017 IPR005183 Domain of unknown function DUF305 CAK77_RS22610 19a5a0a93ef4975049bb8bafa95f7bbb 209 Gene3D G3DSA:1.20.1260.10 57 208 2.1E-55 T 06-07-2017 IPR012347 Ferritin-related CAK77_RS23060 151841a444231bd0762296f495e175ca 357 Gene3D G3DSA:3.40.50.720 1 214 4.9E-31 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS23060 151841a444231bd0762296f495e175ca 357 SUPERFAMILY SSF51735 3 165 3.61E-13 T 06-07-2017 IPR016040 NAD(P)-binding domain CAK77_RS19330 5ba48878c44d529be04fca583b58279d 198 Pfam PF13548 Domain of unknown function (DUF4126) 10 180 4.8E-47 T 06-07-2017 IPR025196 Domain of unknown function DUF4126 CAK77_RS15315 c4c7d47d6f250fcaf88978f5971f0eb8 454 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 164 359 6.9E-18 T 06-07-2017 IPR018713 Domain of unknown function DUF2236 CAK77_RS05670 5419344de8f3c1c36a2a6e7df7f7af54 214 Pfam PF10738 Probable lipoprotein LpqN 44 212 5.2E-51 T 06-07-2017 IPR019674 Lipoprotein LpqT, predicted CAK77_RS04500 b7f1fbd388769563f5d2e97caa472ad9 115 Pfam PF02656 Domain of unknown function (DUF202) 14 79 1.1E-16 T 06-07-2017 IPR003807 Domain of unknown function DUF202 CAK77_RS22855 e81495e96a08b5556c6cddb6c9db36e6 159 Pfam PF04306 Protein of unknown function (DUF456) 21 156 1.3E-28 T 06-07-2017 IPR007403 Protein of unknown function DUF456 CAK77_RS04795 87a1c625e2fea22d7d7d8426a02c87b1 248 Pfam PF03883 Protein of unknown function (DUF328) 2 217 1.6E-35 T 06-07-2017 IPR005583 Peroxide stress protein YaaA CAK77_RS18535 048c95f31d65abcd4a39e4bf130921af 452 Pfam PF16751 Anti-sigma-D factor RsdA to sigma factor binding region 22 67 1.7E-17 T 06-07-2017 IPR031928 Anti-sigma-D factor RsdA, sigma factor binding region CAK77_RS24120 f3d11fcd27d32c827435a3aced99994d 261 Pfam PF08044 Domain of unknown function (DUF1707) 3 55 1.6E-17 T 06-07-2017 IPR012551 Protein of unknown function DUF1707 CAK77_RS10340 43ab59bf3060c55e6fc5752cba9422cd 230 Pfam PF03458 UPF0126 domain 117 191 1.2E-18 T 06-07-2017 IPR005115 Uncharacterised domain UPF0126 CAK77_RS10340 43ab59bf3060c55e6fc5752cba9422cd 230 Pfam PF03458 UPF0126 domain 31 105 7.2E-20 T 06-07-2017 IPR005115 Uncharacterised domain UPF0126 CAK77_RS22265 41df19a86124e442502b4d41880df1bf 57 Pfam PF11021 Protein of unknown function (DUF2613) 3 56 3.6E-20 T 06-07-2017 IPR022566 Protein of unknown function DUF2613 CAK77_RS22265 41df19a86124e442502b4d41880df1bf 57 ProDom PD383784 PRECURSOR SIGNAL SECRETED MB0242C RV0236.1/MT0250 ML2569.1 30 56 0.001 T 06-07-2017 CAK77_RS20540 73a38d0a2f0e6fc55146f0a9ab5feb5b 205 SUPERFAMILY SSF52777 11 170 5.89E-25 T 06-07-2017 CAK77_RS20540 73a38d0a2f0e6fc55146f0a9ab5feb5b 205 Pfam PF00668 Condensation domain 8 166 1.7E-18 T 06-07-2017 IPR001242 Condensation domain CAK77_RS16765 5fc58a35d4454bec67964657dc7d8bfe 158 SUPERFAMILY SSF55961 1 130 1.24E-10 T 06-07-2017 CAK77_RS23435 72faeb8da21127fce480e0449b7c045c 463 ProDom PD092006 MEMBRANE YWOB TRANSMEMBRANE 148 250 5.0E-11 T 06-07-2017 IPR020218 Uncharacterised protein family, YwoB, transmembrane CAK77_RS00105 54dc48b0c1daf1d8aee8dd5442dde734 310 Pfam PF12089 Transmembrane domain of unknown function (DUF3566) 195 308 5.9E-40 T 06-07-2017 IPR021949 Domain of unknown function DUF3566. transmembrane CAK77_RS22955 6d2ecac1f9959d7ddd05546ce746fc34 125 Pfam PF04248 Domain of unknown function (DUF427) 27 117 4.4E-35 T 06-07-2017 IPR007361 Domain of unknown function DUF427 CAK77_RS08665 c8d8fd21b48a507ac5cee60cfae40dfc 399 Pfam PF02470 MlaD protein 35 110 1.7E-11 T 06-07-2017 IPR003399 Mce/MlaD CAK77_RS01800 1d02c5a81570fadd6247814458e22bd8 204 Pfam PF04191 Phospholipid methyltransferase 83 181 1.1E-11 T 06-07-2017 IPR007318 Phospholipid methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825|Reactome: R-HSA-1483191 CAK77_RS14490 e3fe729cbf3b19448177d9ac1d7468ec 99 Gene3D G3DSA:3.10.20.300 44 84 6.3E-4 T 06-07-2017 CAK77_RS17580 4a48b9f7f92349d20818e732799f348a 274 SUPERFAMILY SSF53474 26 219 3.15E-12 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS17580 4a48b9f7f92349d20818e732799f348a 274 Gene3D G3DSA:3.40.50.1820 25 226 9.4E-16 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS17580 4a48b9f7f92349d20818e732799f348a 274 Pfam PF01738 Dienelactone hydrolase family 27 151 6.6E-9 T 06-07-2017 IPR002925 Dienelactone hydrolase GO:0016787 CAK77_RS22460 b66628cd95bdc1f4268bfb4dbc91d6dd 398 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 161 260 1.3E-7 T 06-07-2017 IPR024516 Mammalian cell entry, C-terminal CAK77_RS22460 b66628cd95bdc1f4268bfb4dbc91d6dd 398 Pfam PF02470 MlaD protein 41 115 4.2E-11 T 06-07-2017 IPR003399 Mce/MlaD CAK77_RS20450 3c3e24acd8690f519c2b3bc6673a03c4 92 Pfam PF10724 Protein of unknown function (DUF2516) 4 89 3.9E-25 T 06-07-2017 IPR019662 Protein of unknown function DUF2516 CAK77_RS12545 8e8a4bd3bffbbbdb7639cb3ad1404002 371 PIRSF PIRSF005508 3 363 1.5E-135 T 06-07-2017 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 CAK77_RS12545 8e8a4bd3bffbbbdb7639cb3ad1404002 371 Pfam PF01758 Sodium Bile acid symporter family 62 258 9.1E-61 T 06-07-2017 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 CAK77_RS12545 8e8a4bd3bffbbbdb7639cb3ad1404002 371 TIGRFAM TIGR00832 acr3: arsenical-resistance protein 17 345 9.2E-132 T 06-07-2017 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 CAK77_RS16025 f253f8b5ffd248b056990eb63ce4fcf8 101 Pfam PF10611 Protein of unknown function (DUF2469) 1 100 8.2E-51 T 06-07-2017 IPR019592 Protein of unknown function DUF2469 CAK77_RS20910 d05453b1c58e6c0287fe9b14f9926e93 173 SUPERFAMILY SSF51161 2 154 2.08E-40 T 06-07-2017 IPR011004 Trimeric LpxA-like CAK77_RS20910 d05453b1c58e6c0287fe9b14f9926e93 173 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 89 122 4.5E-6 T 06-07-2017 IPR001451 Hexapeptide repeat CAK77_RS20910 d05453b1c58e6c0287fe9b14f9926e93 173 Gene3D G3DSA:2.160.10.10 2 167 9.5E-39 T 06-07-2017 CAK77_RS02940 bdb72f6340a41d477f365d86ca97c9af 151 Pfam PF05423 Mycobacterium membrane protein 19 109 2.0E-7 T 06-07-2017 IPR008693 Transport accessory protein MmpS CAK77_RS14165 7dffbe521ec16efab8cfa798623c6a04 321 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 8 289 3.9E-73 T 06-07-2017 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 CAK77_RS12160 b8357eb3e38390efc55405a68afab671 88 Pfam PF13376 Bacteriocin-protection, YdeI or OmpD-Associated 14 70 2.4E-19 T 06-07-2017 CAK77_RS20405 83e71b05cf1df447ae3bd63bc672cb3b 573 SUPERFAMILY SSF48452 287 384 7.27E-7 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK77_RS20405 83e71b05cf1df447ae3bd63bc672cb3b 573 Gene3D G3DSA:1.25.40.10 221 385 5.3E-10 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAK77_RS15065 78eb56319babf5a01171b3bc82d17f9a 77 Pfam PF11238 Protein of unknown function (DUF3039) 18 74 1.3E-28 T 06-07-2017 IPR021400 Protein of unknown function DUF3039 CAK77_RS15435 1daeb7b3fd62282c1f0b3bb333218ac3 341 SUPERFAMILY SSF47240 20 209 1.31E-35 T 06-07-2017 IPR009078 Ferritin-like superfamily CAK77_RS02690 122c6d509defac19467bbff854050d25 139 SUPERFAMILY SSF51679 15 134 8.41E-6 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS02690 122c6d509defac19467bbff854050d25 139 Gene3D G3DSA:3.20.20.30 6 134 5.1E-5 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS13095 137bbb6de31e09d6aae06c4026f37db1 124 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 21 110 3.1E-15 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CAK77_RS20945 a2fcb04c95b2841b88d957c7b134a166 390 Pfam PF06742 Protein of unknown function (DUF1214) 78 163 0.0025 T 06-07-2017 IPR010621 Domain of unknown function DUF1214 CAK77_RS23540 3ccdab929f1eb25c9fe629ccb68c136e 231 Pfam PF04471 Restriction endonuclease 107 216 4.0E-30 T 06-07-2017 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 CAK77_RS23540 3ccdab929f1eb25c9fe629ccb68c136e 231 Gene3D G3DSA:3.40.1350.10 102 218 1.3E-35 T 06-07-2017 IPR011856 tRNA endonuclease-like domain GO:0003676|GO:0004518 Reactome: R-HSA-6784531 CAK77_RS23540 3ccdab929f1eb25c9fe629ccb68c136e 231 SUPERFAMILY SSF52980 111 217 1.25E-24 T 06-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CAK77_RS10045 337ed12ab20983c795ba7e7971aa3153 289 Pfam PF10118 Predicted metal-dependent hydrolase 15 263 1.1E-75 T 06-07-2017 IPR016516 Uncharacterised conserved protein UCP07580 CAK77_RS10045 337ed12ab20983c795ba7e7971aa3153 289 PIRSF PIRSF007580 1 282 9.2E-95 T 06-07-2017 IPR016516 Uncharacterised conserved protein UCP07580 CAK77_RS23750 8366bf5590f61fa2c3e76e97f10239d4 423 Pfam PF03929 PepSY-associated TM region 13 381 1.3E-27 T 06-07-2017 IPR005625 PepSY-associated TM protein CAK77_RS22895 9e6f2202cccd63780accf44f73c9537b 286 Pfam PF02405 Permease MlaE 69 273 4.5E-52 T 06-07-2017 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 CAK77_RS12610 70342232b10f71e57d62c137444c961b 433 SUPERFAMILY SSF116734 22 210 6.7E-25 T 06-07-2017 CAK77_RS12610 70342232b10f71e57d62c137444c961b 433 SUPERFAMILY SSF116734 221 426 3.76E-23 T 06-07-2017 CAK77_RS13495 21c1ea56574fa3eaae69c58a0ab4aab2 328 Pfam PF02628 Cytochrome oxidase assembly protein 27 301 3.5E-12 T 06-07-2017 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 CAK77_RS06890 721b200803a7d1d067e21950a26874c1 201 Pfam PF05076 Suppressor of fused protein (SUFU) 35 195 7.3E-29 T 06-07-2017 IPR020941 Suppressor of fused-like domain Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5610787|Reactome: R-HSA-5632684 CAK77_RS08580 4ce2bb374f2c3cd1158bf4f06bc8124d 363 Pfam PF00487 Fatty acid desaturase 75 341 1.6E-23 T 06-07-2017 IPR005804 Fatty acid desaturase domain GO:0006629 CAK77_RS06995 48099ccd6384b87e19bb515bf1fd8ef1 83 SUPERFAMILY SSF54427 3 75 5.42E-6 T 06-07-2017 IPR032710 NTF2-like domain CAK77_RS05370 aa58589022c265f07f427fe375902166 259 Gene3D G3DSA:3.90.226.10 2 258 2.1E-63 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS05370 aa58589022c265f07f427fe375902166 259 Pfam PF00378 Enoyl-CoA hydratase/isomerase 15 258 8.8E-43 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAK77_RS05370 aa58589022c265f07f427fe375902166 259 SUPERFAMILY SSF52096 4 258 5.45E-65 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAK77_RS03285 4f74ac0e7e69d01670050939993e1933 154 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 6 106 7.5E-24 T 06-07-2017 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 CAK77_RS21640 db18ca8ee62268967b17adce8c326224 126 Pfam PF05423 Mycobacterium membrane protein 16 98 4.7E-6 T 06-07-2017 IPR008693 Transport accessory protein MmpS CAK77_RS03980 8ebef7d233cc11f9d4e55053590bbcb3 157 Pfam PF14340 Domain of unknown function (DUF4395) 13 148 1.4E-44 T 06-07-2017 IPR025508 Domain of unknown function DUF4395 CAK77_RS06795 97b583ec510e98f57900f08cb06b0119 224 Pfam PF04191 Phospholipid methyltransferase 110 203 7.1E-15 T 06-07-2017 IPR007318 Phospholipid methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825|Reactome: R-HSA-1483191 CAK77_RS12035 e711c98a832ea5b5b4922128dbc9293b 235 Pfam PF11575 FhuF 2Fe-2S C-terminal domain 205 227 2.9E-7 T 06-07-2017 IPR024726 Ferric iron reductase, C-terminal GO:0051537 CAK77_RS09540 922b865a3bc9666e331cb61010c189c5 288 PRINTS PR01217 Proline rich extensin signature 166 187 3.6E-9 T 06-07-2017 CAK77_RS09540 922b865a3bc9666e331cb61010c189c5 288 PRINTS PR01217 Proline rich extensin signature 111 123 3.6E-9 T 06-07-2017 CAK77_RS09540 922b865a3bc9666e331cb61010c189c5 288 PRINTS PR01217 Proline rich extensin signature 132 148 3.6E-9 T 06-07-2017 CAK77_RS09540 922b865a3bc9666e331cb61010c189c5 288 PRINTS PR01217 Proline rich extensin signature 154 166 3.6E-9 T 06-07-2017 CAK77_RS12940 a81ce9ec2bd1bedb36a518e950bd273f 484 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 7 460 2.2E-160 T 06-07-2017 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0016020 CAK77_RS12940 a81ce9ec2bd1bedb36a518e950bd273f 484 PIRSF PIRSF006446 1 482 8.7E-127 T 06-07-2017 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0016020 CAK77_RS06085 9d0c575fbb3c065b5d49ce822acc9c5b 181 Gene3D G3DSA:3.10.450.50 6 133 3.5E-5 T 06-07-2017 IPR032710 NTF2-like domain CAK77_RS06085 9d0c575fbb3c065b5d49ce822acc9c5b 181 SUPERFAMILY SSF54427 16 134 1.86E-19 T 06-07-2017 IPR032710 NTF2-like domain CAK77_RS00740 7152bf1343d925e3c9daab307f9d4506 132 Gene3D G3DSA:1.10.260.40 38 86 2.8E-7 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK77_RS20210 80f36c591b49379881694cc82893aff4 344 Pfam PF02470 MlaD protein 41 114 1.1E-9 T 06-07-2017 IPR003399 Mce/MlaD CAK77_RS07425 5d6de01fcb8c09193edef306e2810e63 195 Pfam PF09438 Domain of unknown function (DUF2017) 12 190 4.7E-59 T 06-07-2017 IPR018561 Domain of unknown function DUF2017 CAK77_RS00295 b05354b9cb0d10b0ff77eee3c740eee7 287 SUPERFAMILY SSF144091 67 245 9.16E-38 T 06-07-2017 CAK77_RS00295 b05354b9cb0d10b0ff77eee3c740eee7 287 Pfam PF01694 Rhomboid family 110 242 6.9E-29 T 06-07-2017 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CAK77_RS00295 b05354b9cb0d10b0ff77eee3c740eee7 287 Gene3D G3DSA:1.20.1540.10 67 242 4.4E-36 T 06-07-2017 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CAK77_RS19650 f72b9dbb98541c37a37ffa19ea53b15f 121 Pfam PF16170 Domain of unknown function (DUF4873) 20 111 9.7E-31 T 06-07-2017 IPR032371 Domain of unknown function DUF4873 CAK77_RS20145 ac919717a43d0cb1c638c5c83369bd76 294 SUPERFAMILY SSF48613 53 192 6.34E-8 T 06-07-2017 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CAK77_RS20145 ac919717a43d0cb1c638c5c83369bd76 294 Pfam PF10118 Predicted metal-dependent hydrolase 13 271 2.0E-62 T 06-07-2017 IPR016516 Uncharacterised conserved protein UCP07580 CAK77_RS20145 ac919717a43d0cb1c638c5c83369bd76 294 Gene3D G3DSA:1.20.910.10 65 192 1.8E-4 T 06-07-2017 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CAK77_RS20145 ac919717a43d0cb1c638c5c83369bd76 294 PIRSF PIRSF007580 2 292 7.6E-72 T 06-07-2017 IPR016516 Uncharacterised conserved protein UCP07580 CAK77_RS21670 719eb95e2a2833b3b9143d85e5b03761 90 Pfam PF09981 Uncharacterized protein conserved in bacteria (DUF2218) 6 87 1.3E-16 T 06-07-2017 IPR014543 Uncharacterised conserved protein UCP028291 CAK77_RS20875 6d02a14031fc149d7bff5db6c42c6041 208 SMART SM00464 1 196 3.1E-29 T 06-07-2017 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 CAK77_RS20875 6d02a14031fc149d7bff5db6c42c6041 208 SUPERFAMILY SSF88697 3 193 1.69E-41 T 06-07-2017 IPR015947 PUA-like domain CAK77_RS20875 6d02a14031fc149d7bff5db6c42c6041 208 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 2 192 6.9E-23 T 06-07-2017 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 CAK77_RS14045 c0ba0d55403104ac44e1b0ca46ddebd2 140 PIRSF PIRSF021591 1 140 9.0E-30 T 06-07-2017 IPR016793 Uncharacterised conserved protein UCP021591 CAK77_RS14925 96f1f1615150150e356a6234a37bd940 220 Gene3D G3DSA:3.40.50.1820 32 197 1.7E-13 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS14925 96f1f1615150150e356a6234a37bd940 220 SUPERFAMILY SSF53474 3 198 2.37E-17 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS08130 e41055d1be2e202271a3496b4e9a559f 235 SUPERFAMILY SSF54001 175 228 4.41E-23 T 06-07-2017 CAK77_RS08130 e41055d1be2e202271a3496b4e9a559f 235 SUPERFAMILY SSF54001 15 134 4.41E-23 T 06-07-2017 CAK77_RS08130 e41055d1be2e202271a3496b4e9a559f 235 Gene3D G3DSA:2.30.30.330 180 226 3.4E-49 T 06-07-2017 CAK77_RS08130 e41055d1be2e202271a3496b4e9a559f 235 Gene3D G3DSA:2.30.30.330 13 139 3.4E-49 T 06-07-2017 CAK77_RS17180 69f2fac3b05c2b97a4fd7f4233f6fc0b 346 Pfam PF01757 Acyltransferase family 11 322 1.5E-19 T 06-07-2017 IPR002656 Acyltransferase 3 GO:0016747 CAK77_RS09160 7d60467f68128c0eff5046d4a191cc0e 352 Pfam PF09994 Uncharacterized alpha/beta hydrolase domain (DUF2235) 3 262 1.3E-67 T 06-07-2017 IPR018712 Domain of unknown function DUF2235 CAK77_RS09160 7d60467f68128c0eff5046d4a191cc0e 352 SUPERFAMILY SSF53474 3 121 3.85E-5 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS10665 cf90f125cdc53312b690493ee4f0ec30 271 Pfam PF14230 Domain of unknown function (DUF4333) 181 263 5.2E-26 T 06-07-2017 IPR025637 Domain of unknown function DUF4333 CAK77_RS10270 591b8918a3e5ee275e8cf210e876ddf7 110 Pfam PF05305 Protein of unknown function (DUF732) 14 107 5.9E-11 T 06-07-2017 IPR007969 Domain of unknown function DUF732 CAK77_RS23305 eee84ca267899deca533bfb8269bd293 171 Gene3D G3DSA:3.90.1720.10 5 106 1.2E-9 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain CAK77_RS23305 eee84ca267899deca533bfb8269bd293 171 SUPERFAMILY SSF54001 5 108 2.21E-8 T 06-07-2017 CAK77_RS05445 fea51ffa3233a4365ac1848ec1741a33 224 Pfam PF08666 SAF domain 55 111 3.7E-8 T 06-07-2017 IPR013974 SAF domain Reactome: R-HSA-4085001 CAK77_RS05445 fea51ffa3233a4365ac1848ec1741a33 224 SMART SM00858 54 116 9.1E-9 T 06-07-2017 IPR013974 SAF domain Reactome: R-HSA-4085001 CAK77_RS02230 b88ef03dd9eff1c21a2c2d0b2441fa2b 179 Pfam PF13392 HNH endonuclease 9 53 3.0E-10 T 06-07-2017 IPR003615 HNH nuclease CAK77_RS02230 b88ef03dd9eff1c21a2c2d0b2441fa2b 179 SUPERFAMILY SSF54060 8 56 2.59E-7 T 06-07-2017 CAK77_RS10815 4b93c70aafb3ad6e6df45c23034ec36a 365 Pfam PF00296 Luciferase-like monooxygenase 4 334 7.9E-89 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS10815 4b93c70aafb3ad6e6df45c23034ec36a 365 SUPERFAMILY SSF51679 23 362 5.1E-94 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS10815 4b93c70aafb3ad6e6df45c23034ec36a 365 Gene3D G3DSA:3.20.20.30 295 363 2.2E-101 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS10815 4b93c70aafb3ad6e6df45c23034ec36a 365 Gene3D G3DSA:3.20.20.30 6 261 2.2E-101 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAK77_RS21845 3fdd271e0cd884705800735acbe003ff 409 TIGRFAM TIGR02778 ligD_pol: DNA ligase D, polymerase domain 24 268 2.0E-67 T 06-07-2017 IPR014145 DNA ligase D, polymerase domain CAK77_RS04455 6be297f4bfe9b657dc178be85e48576a 81 Pfam PF10745 Protein of unknown function (DUF2530) 6 81 4.6E-31 T 06-07-2017 IPR019681 Protein of unknown function DUF2530 CAK77_RS24175 b2d6a9f3472a7921e24b3617cef4a157 228 Pfam PF14032 PknH-like extracellular domain 43 223 7.1E-31 T 06-07-2017 IPR026954 PknH-like extracellular domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 CAK77_RS17920 c28fb86bda4853c6d58bbe5cb4a31f0f 355 SUPERFAMILY SSF53697 63 351 4.67E-40 T 06-07-2017 CAK77_RS01030 9e2ad1d0d8668083e658da936b907179 304 Pfam PF01040 UbiA prenyltransferase family 35 277 1.3E-20 T 06-07-2017 IPR000537 UbiA prenyltransferase family GO:0004659|GO:0016021 CAK77_RS22885 41a593f4af8f8f99c3e4219ad1fd3c2a 350 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 14 263 1.2E-52 T 06-07-2017 IPR005693 Virulence factor Mce protein CAK77_RS22885 41a593f4af8f8f99c3e4219ad1fd3c2a 350 Pfam PF02470 MlaD protein 37 111 4.9E-16 T 06-07-2017 IPR003399 Mce/MlaD CAK77_RS03465 0b4552622021807280e3345d8f56e060 468 Pfam PF00823 PPE family 10 164 3.6E-58 T 06-07-2017 IPR000030 PPE family CAK77_RS03465 0b4552622021807280e3345d8f56e060 468 SUPERFAMILY SSF140459 5 177 1.23E-60 T 06-07-2017 CAK77_RS07395 1c8b50b5f03b3cbe42b443c44e8d11e2 481 SUPERFAMILY SSF55486 50 210 1.06E-9 T 06-07-2017 CAK77_RS05745 1e9dcad43c74f2cf7f5072694d736d8e 683 Pfam PF09375 Imelysin 442 640 4.6E-6 T 06-07-2017 CAK77_RS05745 1e9dcad43c74f2cf7f5072694d736d8e 683 Pfam PF03239 Iron permease FTR1 family 9 264 2.0E-40 T 06-07-2017 IPR004923 Iron permease FTR1/Fip1/EfeU GO:0005381|GO:0006827|GO:0016020|GO:0033573 CAK77_RS20825 3defb789813d05968e6c0477f597d62d 255 Pfam PF02405 Permease MlaE 36 247 1.0E-61 T 06-07-2017 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 CAK77_RS20455 282682bc18a8753d56c12d9bd61d9d86 214 ProDom PD082580 HEPARIN-BINDING HEMAGGLUTININ ADHESIN GLYCOPROTEIN DIRECT VIRULENCE SEQUENCING CELL ADHESION HOMOLOG 51 160 2.0E-30 T 06-07-2017 IPR020340 Heparin-binding haemagglutinin, bacteria GO:0007155|GO:0008201|GO:0009405|GO:0009986 CAK77_RS00960 03719e24ffd246673dcc74f758620583 321 Pfam PF03060 Nitronate monooxygenase 93 310 1.3E-29 T 06-07-2017 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 CAK77_RS00960 03719e24ffd246673dcc74f758620583 321 Pfam PF03060 Nitronate monooxygenase 5 64 1.6E-12 T 06-07-2017 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 CAK77_RS00960 03719e24ffd246673dcc74f758620583 321 SUPERFAMILY SSF51412 2 315 1.98E-52 T 06-07-2017 CAK77_RS00960 03719e24ffd246673dcc74f758620583 321 Gene3D G3DSA:3.20.20.70 2 304 3.0E-53 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAK77_RS15450 9f718dfeca769b59a613695d685acd21 240 Pfam PF09948 Predicted metal-binding integral membrane protein (DUF2182) 58 232 1.3E-38 T 06-07-2017 IPR018688 Protein of unknown function DUF2182, transmembrane, metal-binding CAK77_RS02190 437885ee20623932181ea25ccbed388d 128 SUPERFAMILY SSF143100 3 45 5.62E-7 T 06-07-2017 CAK77_RS22260 1d2d237ace35f55494d143616a070e55 355 Gene3D G3DSA:2.60.120.260 146 241 4.4E-5 T 06-07-2017 IPR008979 Galactose-binding domain-like CAK77_RS22260 1d2d237ace35f55494d143616a070e55 355 SUPERFAMILY SSF49785 158 264 4.08E-5 T 06-07-2017 IPR008979 Galactose-binding domain-like CAK77_RS21335 e9f86ce2a066566a86cb73646bf13465 257 Pfam PF06966 Protein of unknown function (DUF1295) 18 244 2.4E-68 T 06-07-2017 IPR010721 Protein of unknown function DUF1295 CAK77_RS08170 cf75c10613bf589dd401a324acc48bda 386 Pfam PF07907 YibE/F-like protein 137 374 1.4E-70 T 06-07-2017 IPR012507 YibE/F-like CAK77_RS00895 35f78edc4293aacade1ef47f4dc20c7e 249 Pfam PF02308 MgtC family 23 150 1.2E-32 T 06-07-2017 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CAK77_RS00895 35f78edc4293aacade1ef47f4dc20c7e 249 PRINTS PR01837 MgtC/SapB protein signature 79 101 3.1E-41 T 06-07-2017 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CAK77_RS00895 35f78edc4293aacade1ef47f4dc20c7e 249 PRINTS PR01837 MgtC/SapB protein signature 26 45 3.1E-41 T 06-07-2017 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CAK77_RS00895 35f78edc4293aacade1ef47f4dc20c7e 249 PRINTS PR01837 MgtC/SapB protein signature 106 130 3.1E-41 T 06-07-2017 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CAK77_RS00895 35f78edc4293aacade1ef47f4dc20c7e 249 PRINTS PR01837 MgtC/SapB protein signature 45 63 3.1E-41 T 06-07-2017 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CAK77_RS19725 f2cf0496f30c350797169a7bf54c164b 149 Pfam PF04075 Domain of unknown function (DUF385) 24 112 3.0E-7 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CAK77_RS22715 1cd41023ebe2a2f972b722f0978020af 402 Pfam PF02470 MlaD protein 41 115 2.9E-12 T 06-07-2017 IPR003399 Mce/MlaD CAK77_RS24040 899e85350a47a0da7be697edabe5b9ec 308 Pfam PF00561 alpha/beta hydrolase fold 29 278 2.2E-24 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAK77_RS24040 899e85350a47a0da7be697edabe5b9ec 308 SUPERFAMILY SSF53474 7 291 1.47E-56 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS24040 899e85350a47a0da7be697edabe5b9ec 308 Gene3D G3DSA:3.40.50.1820 8 289 3.6E-61 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAK77_RS09165 2be5bf63f163ae45f0ae6aad9b567321 456 SUPERFAMILY SSF140459 60 170 3.14E-5 T 06-07-2017 CAK77_RS05210 78f0b1ca852dde74f0c61eeb8fcf7c1c 105 Pfam PF16170 Domain of unknown function (DUF4873) 9 96 2.0E-26 T 06-07-2017 IPR032371 Domain of unknown function DUF4873 CAK77_RS02480 daa2bfdb18e0229a4840c6ca02d3e1ed 258 Pfam PF00482 Type II secretion system (T2SS), protein F 93 211 7.1E-11 T 06-07-2017 IPR018076 Type II secretion system F domain CAK77_RS06245 49f1cafeacdc3331befbfb89f92fbcf4 78 Gene3D G3DSA:1.10.287.110 6 33 2.4E-4 T 06-07-2017 IPR001623 DnaJ domain CAK77_RS23125 217d6ee681f9558844f2c229d8698dc0 309 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 39 272 1.0E-42 T 06-07-2017 IPR018713 Domain of unknown function DUF2236 CAK77_RS12240 6e5a9bcd7744554ecfc935fe66ee55d0 158 Pfam PF04120 Low affinity iron permease 38 124 1.5E-23 T 06-07-2017 IPR007251 Low affinity iron permease, Fet4 GO:0055085 CAK77_RS12375 64feae7af1b2640e8b495b41ed63a5a6 350 Pfam PF01757 Acyltransferase family 13 318 3.3E-17 T 06-07-2017 IPR002656 Acyltransferase 3 GO:0016747 CAK77_RS15970 19dd9872d2c5561bad2c1c228e082cea 272 Pfam PF06912 Protein of unknown function (DUF1275) 50 259 2.3E-29 T 06-07-2017 IPR010699 Protein of unknown function DUF1275 CAK77_RS15165 d96109e9563e73ce72af57fbec0823a2 448 Pfam PF03993 Domain of Unknown Function (DUF349) 136 209 2.3E-14 T 06-07-2017 IPR007139 Protein of unknown function DUF349 CAK77_RS15165 d96109e9563e73ce72af57fbec0823a2 448 Pfam PF03993 Domain of Unknown Function (DUF349) 291 363 5.8E-20 T 06-07-2017 IPR007139 Protein of unknown function DUF349 CAK77_RS15165 d96109e9563e73ce72af57fbec0823a2 448 Pfam PF03993 Domain of Unknown Function (DUF349) 213 286 7.5E-22 T 06-07-2017 IPR007139 Protein of unknown function DUF349 CAK77_RS09060 353b59690134b25a1961e55d9f6aad27 146 Pfam PF10517 Electron transfer DM13 59 145 1.5E-10 T 06-07-2017 IPR019545 DM13 domain CAK77_RS01300 e5324e675e6dd4033e15e3639141b1fc 623 Pfam PF06259 Alpha/beta hydrolase 292 451 1.5E-7 T 06-07-2017 IPR010427 Protein of unknown function DUF1023 CAK77_RS13570 7974763e1110761e07cea4bc0a795bcc 549 Pfam PF09972 Predicted membrane protein (DUF2207) 40 502 2.4E-35 T 06-07-2017 IPR018702 Protein of unknown function DUF2207, membrane CAK77_RS13035 11256775cba41916b49e3ec4723219f8 147 Pfam PF05423 Mycobacterium membrane protein 11 147 9.7E-35 T 06-07-2017 IPR008693 Transport accessory protein MmpS CAK77_RS17100 bcd5c42a781f7d95cfb4c1ff30e35c2b 225 Gene3D G3DSA:3.40.50.850 7 225 5.2E-67 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAK77_RS17100 bcd5c42a781f7d95cfb4c1ff30e35c2b 225 SUPERFAMILY SSF52499 8 225 7.2E-58 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAK77_RS17100 bcd5c42a781f7d95cfb4c1ff30e35c2b 225 Pfam PF00857 Isochorismatase family 23 212 2.1E-42 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAK77_RS00260 a92f8088d85c71d4c11e0c925e5746fe 107 Pfam PF03860 Domain of Unknown Function (DUF326) 65 83 2.8E-4 T 06-07-2017 IPR005560 Protein of unknown function DUF326 CAK77_RS22280 9ba627f0aaa13a67854d49fff3766230 393 Pfam PF11271 Protein of unknown function (DUF3068) 11 342 9.4E-92 T 06-07-2017 IPR021424 Protein of unknown function DUF3068 CAK77_RS22865 4f6e3ce449185f24c74acdcdd6615a96 452 Pfam PF02470 MlaD protein 61 135 1.1E-12 T 06-07-2017 IPR003399 Mce/MlaD CAK77_RS20580 57636f554b68f389a365e46ac7f7c6e5 374 Pfam PF01757 Acyltransferase family 24 336 8.3E-19 T 06-07-2017 IPR002656 Acyltransferase 3 GO:0016747 CAK77_RS05365 1a7d042445d9170978b6a9606cfa200b 200 Pfam PF08044 Domain of unknown function (DUF1707) 12 64 3.5E-20 T 06-07-2017 IPR012551 Protein of unknown function DUF1707 CAK77_RS22530 007810fda3c00df4556e27306628bced 130 Pfam PF11255 Protein of unknown function (DUF3054) 21 124 4.8E-34 T 06-07-2017 IPR021414 Protein of unknown function DUF3054 CAK77_RS21785 b9d2f5c763b5a1fc43d9b999c020c02b 312 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 53 277 4.4E-47 T 06-07-2017 IPR018713 Domain of unknown function DUF2236 CAK77_RS02800 92009659462c59276d64c751d124055f 155 Pfam PF11377 Protein of unknown function (DUF3180) 9 147 4.4E-38 T 06-07-2017 IPR021517 Protein of unknown function DUF3180 CAK77_RS20635 a40b956cbb2126df5181510cffbd3053 138 Pfam PF05423 Mycobacterium membrane protein 1 138 3.5E-56 T 06-07-2017 IPR008693 Transport accessory protein MmpS CAK77_RS18900 4cda67df9998a34d5be1408aa1d153b6 379 Pfam PF01594 Domain of unknown function DUF20 13 345 2.6E-51 T 06-07-2017 IPR002549 Transmembrane protein TqsA-like CAK77_RS06330 e903392a1601d2cf96b50e30531b6283 62 Pfam PF04024 PspC domain 6 61 1.1E-18 T 06-07-2017 IPR007168 Phage shock protein, PspC, N-terminal CAK77_RS10420 d64a1a057d8d886ecfe1ece5b31b9f4d 259 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 39 184 7.6E-28 T 06-07-2017 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAK77_RS15085 8713597b781110bba6094d5707dbb5ee 349 Pfam PF13830 Domain of unknown function (DUF4192) 19 320 5.5E-73 T 06-07-2017 IPR025447 Protein of unknown function DUF4192 CAK77_RS08055 4f2585d68944b3581b15d1a7e6aaeea5 191 SUPERFAMILY SSF47413 5 78 6.25E-5 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK77_RS08055 4f2585d68944b3581b15d1a7e6aaeea5 191 Gene3D G3DSA:1.10.260.40 4 76 4.4E-6 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAK77_RS16140 2408c3cc75822eef50cf50ad8f21469a 273 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 1 203 2.5E-13 T 06-07-2017 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 CAK77_RS01745 4743d8279e5a0dfc8181028660090b18 388 Pfam PF13810 Domain of unknown function (DUF4185) 63 378 1.2E-50 T 06-07-2017 IPR025442 Domain of unknown function DUF4185 CAK77_RS24170 5f5bf9a79775630d86cf60234fc629dc 226 Pfam PF14032 PknH-like extracellular domain 42 223 9.9E-30 T 06-07-2017 IPR026954 PknH-like extracellular domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 CAK77_RS15640 b2bd006c53d107aa11e2422eb497da0b 258 Pfam PF02361 Cobalt transport protein 17 229 8.5E-28 T 06-07-2017 IPR003339 ABC/ECF transporter, transmembrane component CAK77_RS05895 aa9c0f66ead4ae5204f67456186822df 208 Pfam PF11259 Protein of unknown function (DUF3060) 145 202 1.2E-20 T 06-07-2017 IPR021417 Protein of unknown function DUF3060 CAK77_RS19890 6c44569b169639d58c41778dc2b13473 112 Pfam PF14012 Protein of unknown function (DUF4229) 16 83 2.8E-22 T 06-07-2017 IPR025323 Protein of unknown function DUF4229 CAK77_RS16315 fe9a092da89bf33974c56e3e5cb7d96e 236 Pfam PF07510 Protein of unknown function (DUF1524) 90 200 1.1E-10 T 06-07-2017 IPR011089 Domain of unknown function DUF1524 CAK77_RS20975 7bfbf5b9c86791affbb0d547d6eb098d 154 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 68 151 5.6E-12 T 06-07-2017 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain CAK77_RS01505 b8f5a5dd977797be3605a403031e6dcb 428 Pfam PF13546 DDE superfamily endonuclease 38 253 7.1E-33 T 06-07-2017 CAK77_RS09145 f0c35fd2bf12556bdbf9876f3b6ba9b0 161 Pfam PF13630 SdpI/YhfL protein family 50 113 1.5E-7 T 06-07-2017 IPR025962 SdpI/YhfL protein family CAK77_RS00715 ac881b320aa7fbafcd502b49927ff79c 222 Pfam PF07987 Domain of unkown function (DUF1775) 29 162 6.5E-34 T 06-07-2017 IPR012533 GLE1, N-terminal, bacteria CAK77_RS15240 eec24eb713e086d4e86ce2e32c83ace5 64 Pfam PF11248 Protein of unknown function (DUF3046) 1 61 1.8E-29 T 06-07-2017 IPR021408 Protein of unknown function DUF3046 CAK77_RS04065 b98504a4305b28587b65e1105d35ac6e 59 Pfam PF11139 Sap, sulfolipid-1-addressing protein 3 56 3.7E-16 T 06-07-2017 IPR021315 Glycolipid exporter Gap/Sap CAK77_RS15515 aa72e35a97cdd8ccf60d3fa42f682f23 89 Pfam PF10041 Uncharacterized conserved protein (DUF2277) 1 84 1.1E-34 T 06-07-2017 IPR018735 Protein of unknown function DUF2277 CAK77_RS02510 9a57aa2a23686e94360588498cf341b7 153 Pfam PF05423 Mycobacterium membrane protein 18 153 4.3E-36 T 06-07-2017 IPR008693 Transport accessory protein MmpS CAK77_RS00910 1c30790c55518e2a5726630446af3e2b 123 SUPERFAMILY SSF140453 24 121 4.05E-5 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like CAK77_RS00910 1c30790c55518e2a5726630446af3e2b 123 Pfam PF00934 PE family 24 112 7.0E-14 T 06-07-2017 IPR000084 PE-PGRS family, N-terminal CAK77_RS20980 d3fe4add7b4ffb9d7137578fdb132d53 115 Pfam PF11662 Protein of unknown function (DUF3263) 34 105 1.1E-36 T 06-07-2017 IPR021678 Protein of unknown function DUF3263 CAK77_RS07845 f2d4100c3dc44047ae4c67a45cf20187 170 SUPERFAMILY SSF160631 13 158 4.32E-9 T 06-07-2017 CAK77_RS20445 11ccb95ffa2813e9659dae83c08f5717 150 Pfam PF10783 Protein of unknown function (DUF2599) 54 146 3.2E-33 T 06-07-2017 IPR019719 Protein of unknown function DUF2599 CAK77_RS14565 f38adac8c7e168ae59ff139669db01e3 156 Pfam PF16708 Lipoprotein confined to pathogenic Mycobacterium 2 153 7.1E-44 T 06-07-2017 IPR032018 Putative lipoprotein, pathogenic bacteria CAK77_RS06770 1d33c75463eeaa0efcc97f17dd86c0a2 55 Pfam PF11314 Protein of unknown function (DUF3117) 4 53 6.0E-29 T 06-07-2017 IPR021465 Protein of unknown function DUF3117 CAK77_RS01370 9b54ecc5e64d225af90b3f15c75063de 176 TIGRFAM TIGR03941 tRNA_deam_assoc: putative tRNA adenosine deaminase-associated protein 18 169 2.7E-52 T 06-07-2017 IPR023869 tRNA adenosine deaminase-associated protein, putative CAK77_RS02015 2e7ad8c2df935845883d2a32f88af59e 411 Pfam PF01757 Acyltransferase family 7 356 1.3E-22 T 06-07-2017 IPR002656 Acyltransferase 3 GO:0016747 CAK77_RS04740 26b1f9ea63ca789914c3ab8361b57092 71 Pfam PF14013 MT0933-like antitoxin protein 8 56 5.5E-16 T 06-07-2017 IPR028037 Antitoxin Rv0909/MT0933 CAK77_RS06860 357758ae3a1343e38b30f61a4919c04a 221 Pfam PF13828 Domain of unknown function (DUF4190) 142 206 1.6E-18 T 06-07-2017 IPR025241 Domain of unknown function DUF4190 CAK77_RS02935 ce49bf7ec6e9627f947a2279f31bf910 121 Pfam PF05423 Mycobacterium membrane protein 23 98 1.9E-10 T 06-07-2017 IPR008693 Transport accessory protein MmpS CAK77_RS06425 952512ab8ea1de73e654c2ca4c1ccb96 181 Pfam PF12079 Protein of unknown function (DUF3558) 1 178 3.6E-18 T 06-07-2017 IPR024520 Protein of unknown function DUF3558