locus-tag	class	description
RE97_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
RE97_RS00010	COG0592	DNA-directed DNA polymerase activity
RE97_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
RE97_RS00020	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
RE97_RS00025	COG0187	DNA topoisomerase II activity
RE97_RS00055	COG3328	transposase activity
RE97_RS00085	COG0318	PFAM AMP-dependent synthetase and ligase
RE97_RS00105	COG3547	Transposase (IS116 IS110 IS902 family)
RE97_RS00115	COG1937	Protein conserved in bacteria
RE97_RS00130	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
RE97_RS00135	COG3433	isochorismatase activity
RE97_RS00135	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RE97_RS00135	COG2226	methyltransferase
RE97_RS00140	COG2226	methyltransferase
RE97_RS00140	COG3433	isochorismatase activity
RE97_RS00140	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RE97_RS00145	COG3433	isochorismatase activity
RE97_RS00145	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RE97_RS00145	COG2226	methyltransferase
RE97_RS00150	COG0477	Major facilitator Superfamily
RE97_RS00165	COG1132	(ABC) transporter
RE97_RS00165	COG2375	cellular response to nickel ion
RE97_RS00180	COG1129	ABC transporter
RE97_RS00200	COG1120	ATPase activity
RE97_RS00205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RE97_RS00240	COG0346	lactoylglutathione lyase activity
RE97_RS00255	COG1960	acyl-CoA dehydrogenase activity
RE97_RS00265	COG0318	PFAM AMP-dependent synthetase and ligase
RE97_RS00275	COG2223	nitrite transmembrane transporter activity
RE97_RS00280	COG1309	transcriptional regulator
RE97_RS00290	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
RE97_RS00295	COG1984	allophanate hydrolase subunit 2
RE97_RS00325	COG2146	nitrite reductase [NAD(P)H] activity
RE97_RS00325	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
RE97_RS00345	COG1053	succinate dehydrogenase
RE97_RS00365	COG1960	acyl-CoA dehydrogenase activity
RE97_RS00375	COG0183	Belongs to the thiolase family
RE97_RS00380	COG1028	Short-chain dehydrogenase reductase Sdr
RE97_RS00385	COG2030	dehydratase
RE97_RS00400	COG1472	Belongs to the glycosyl hydrolase 3 family
RE97_RS00410	COG4981	capsule polysaccharide biosynthetic process
RE97_RS00460	COG0583	DNA-binding transcription factor activity
RE97_RS00465	COG0028	Belongs to the TPP enzyme family
RE97_RS00475	COG1012	belongs to the aldehyde dehydrogenase family
RE97_RS00480	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
RE97_RS00520	COG0500	methyltransferase
RE97_RS00530	COG1309	transcriptional regulator
RE97_RS00545	COG1024	Enoyl-CoA hydratase
RE97_RS00555	COG0657	acetylesterase activity
RE97_RS00560	COG0657	acetylesterase activity
RE97_RS00585	COG1024	Enoyl-CoA hydratase
RE97_RS00600	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
RE97_RS00615	COG0220	tRNA (guanine-N7-)-methyltransferase activity
RE97_RS00625	COG2409	Drug exporters of the RND superfamily
RE97_RS00650	COG0243	molybdopterin cofactor binding
RE97_RS00660	COG1376	ErfK ybiS ycfS ynhG family protein
RE97_RS00665	COG2814	Major facilitator Superfamily
RE97_RS00670	COG1937	Protein conserved in bacteria
RE97_RS00675	COG0129	dihydroxy-acid dehydratase activity
RE97_RS00690	COG4122	O-methyltransferase activity
RE97_RS00695	COG1472	Belongs to the glycosyl hydrolase 3 family
RE97_RS00710	COG2267	carboxylic ester hydrolase activity
RE97_RS00750	COG3619	membrane
RE97_RS00765	COG1714	RDD family
RE97_RS00780	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
RE97_RS00805	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
RE97_RS00810	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
RE97_RS00820	COG1802	Transcriptional regulator
RE97_RS00840	COG0657	acetylesterase activity
RE97_RS00845	COG2072	flavoprotein involved in K transport
RE97_RS00865	COG2124	cytochrome p450
RE97_RS00890	COG1960	acyl-CoA dehydrogenase activity
RE97_RS00940	COG1309	transcriptional regulator
RE97_RS00970	COG2365	Tyrosine phosphatase family
RE97_RS00975	COG2365	Tyrosine phosphatase family
RE97_RS00980	COG1028	Short-chain dehydrogenase reductase Sdr
RE97_RS00985	COG1012	belongs to the aldehyde dehydrogenase family
RE97_RS01000	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
RE97_RS01010	COG1741	Belongs to the pirin family
RE97_RS01015	COG0783	Belongs to the Dps family
RE97_RS01045	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
RE97_RS01110	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RE97_RS01130	COG2267	carboxylic ester hydrolase activity
RE97_RS01140	COG1937	Protein conserved in bacteria
RE97_RS01155	COG1129	ABC transporter
RE97_RS01155	COG0842	Transport permease protein
RE97_RS01175	COG3281	Trehalose synthase
RE97_RS01185	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RE97_RS01205	COG0028	Belongs to the TPP enzyme family
RE97_RS01210	COG0583	DNA-binding transcription factor activity
RE97_RS01220	COG1376	ErfK ybiS ycfS ynhG family protein
RE97_RS01230	COG0604	alcohol dehydrogenase
RE97_RS01230	COG3321	synthase
RE97_RS01245	COG2755	lipolytic protein G-D-S-L family
RE97_RS01245	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
RE97_RS01255	COG0028	Belongs to the TPP enzyme family
RE97_RS01265	COG1028	Short-chain dehydrogenase reductase Sdr
RE97_RS01270	COG2072	flavoprotein involved in K transport
RE97_RS01280	COG1028	Short-chain dehydrogenase reductase Sdr
RE97_RS01295	COG0318	PFAM AMP-dependent synthetase and ligase
RE97_RS01300	COG1028	Short-chain dehydrogenase reductase Sdr
RE97_RS01325	COG0318	PFAM AMP-dependent synthetase and ligase
RE97_RS01370	COG0518	GMP synthase (glutamine-hydrolyzing) activity
RE97_RS01370	COG0519	Catalyzes the synthesis of GMP from XMP
RE97_RS01410	COG0406	alpha-ribazole phosphatase activity
RE97_RS01420	COG2030	dehydratase
RE97_RS01435	COG0587	DNA-directed DNA polymerase activity
RE97_RS01445	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
RE97_RS01455	COG5002	protein histidine kinase activity
RE97_RS01460	COG2018	Roadblock/LC7 domain
RE97_RS01475	COG1357	PFAM Pentapeptide repeats (8 copies)
RE97_RS01485	COG1716	ATPase activity
RE97_RS01485	COG0842	Transport permease protein
RE97_RS01485	COG1131	(ABC) transporter
RE97_RS01490	COG1131	(ABC) transporter
RE97_RS01490	COG1716	ATPase activity
RE97_RS01490	COG0842	Transport permease protein
RE97_RS01505	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
RE97_RS01530	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
RE97_RS01535	COG2873	o-acetylhomoserine
RE97_RS01555	COG0180	Tryptophanyl-tRNA synthetase
RE97_RS01560	COG1295	ribonuclease BN
RE97_RS01575	COG2814	Major facilitator Superfamily
RE97_RS01580	COG1686	Belongs to the peptidase S11 family
RE97_RS01590	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
RE97_RS01595	COG1595	DNA-templated transcription, initiation
RE97_RS01605	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
RE97_RS01620	COG2009	succinate dehydrogenase
RE97_RS01650	COG2304	oxidoreductase activity
RE97_RS01655	COG2304	oxidoreductase activity
RE97_RS01665	COG3511	phospholipase C
RE97_RS01675	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
RE97_RS01690	COG1473	amidohydrolase
RE97_RS01695	COG1473	amidohydrolase
RE97_RS01695	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
RE97_RS01710	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
RE97_RS01715	COG0564	pseudouridine synthase activity
RE97_RS01755	COG1201	RNA secondary structure unwinding
RE97_RS01760	COG1309	transcriptional regulator
RE97_RS01765	COG1012	belongs to the aldehyde dehydrogenase family
RE97_RS01775	COG1522	sequence-specific DNA binding
RE97_RS01805	COG1366	Belongs to the anti-sigma-factor antagonist family
RE97_RS01810	COG4770	biotin carboxylase activity
RE97_RS01825	COG0424	maF-like protein
RE97_RS01835	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
RE97_RS01840	COG1053	succinate dehydrogenase
RE97_RS01880	COG4251	negative regulation of phosphorylation
RE97_RS01885	COG0784	Response regulator, receiver
RE97_RS01900	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RE97_RS01905	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
RE97_RS01925	COG1316	TRANSCRIPTIONal
RE97_RS01940	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
RE97_RS01955	COG0778	Nitroreductase
RE97_RS01955	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
RE97_RS01980	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
RE97_RS01990	COG1482	cell wall glycoprotein biosynthetic process
RE97_RS01995	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RE97_RS02000	COG0531	amino acid
RE97_RS02005	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RE97_RS02025	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
RE97_RS02040	COG5000	phosphorelay sensor kinase activity
RE97_RS02040	COG5002	protein histidine kinase activity
RE97_RS02045	COG5401	PFAM Sporulation and spore germination
RE97_RS02055	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
RE97_RS02060	COG0653	protein targeting
RE97_RS02070	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
RE97_RS02075	COG2020	methyltransferase activity
RE97_RS02100	COG2326	polyphosphate kinase activity
RE97_RS02150	COG0183	Belongs to the thiolase family
RE97_RS02155	COG1733	regulation of RNA biosynthetic process
RE97_RS02160	COG1162	GTPase activity
RE97_RS02165	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
RE97_RS02175	COG1403	HNH endonuclease
RE97_RS02190	COG1028	Short-chain dehydrogenase reductase Sdr
RE97_RS02200	COG1028	Short-chain dehydrogenase reductase Sdr
RE97_RS02210	COG1063	alcohol dehydrogenase
RE97_RS02230	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
RE97_RS02265	COG0406	alpha-ribazole phosphatase activity
RE97_RS02280	COG0513	Belongs to the DEAD box helicase family
RE97_RS02325	COG0596	Alpha beta hydrolase
RE97_RS02345	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
RE97_RS02370	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
RE97_RS02385	COG3480	Lon protease (S16) C-terminal proteolytic domain
RE97_RS02390	COG1615	UPF0182 protein
RE97_RS02470	COG2197	response regulator
RE97_RS02475	COG4585	Histidine kinase
RE97_RS02500	COG3707	response regulator
RE97_RS02510	COG0789	Transcriptional regulator
RE97_RS02565	COG1573	uracil-dna glycosylase
RE97_RS02570	COG0028	Belongs to the TPP enzyme family
RE97_RS02575	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
RE97_RS02585	COG1028	Short-chain dehydrogenase reductase Sdr
RE97_RS02595	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
RE97_RS02610	COG2192	nodulation
RE97_RS02615	COG1088	dTDP-glucose 4,6-dehydratase activity
RE97_RS02625	COG0297	glycogen (starch) synthase activity
RE97_RS02665	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
RE97_RS02690	COG2201	protein-glutamate methylesterase activity
RE97_RS02705	COG2201	protein-glutamate methylesterase activity
RE97_RS02730	COG0477	Major facilitator Superfamily
RE97_RS02780	COG0714	Associated with various cellular activities
RE97_RS02795	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
RE97_RS02800	COG1309	transcriptional regulator
RE97_RS02835	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
RE97_RS02840	COG1034	ATP synthesis coupled electron transport
RE97_RS02860	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
RE97_RS02900	COG1960	acyl-CoA dehydrogenase activity
RE97_RS02910	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
RE97_RS02915	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RE97_RS02935	COG1960	acyl-CoA dehydrogenase activity
RE97_RS02945	COG0483	inositol monophosphate 1-phosphatase activity
RE97_RS02995	COG0493	'glutamate synthase
RE97_RS03005	COG0668	transmembrane transport
RE97_RS03015	COG2884	Cell division ATP-binding protein ftsE
RE97_RS03020	COG2177	Part of the ABC transporter FtsEX involved in
RE97_RS03025	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
RE97_RS03050	COG1819	glycosyl
RE97_RS03075	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
RE97_RS03105	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
RE97_RS03115	COG2301	Belongs to the HpcH HpaI aldolase family
RE97_RS03135	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
RE97_RS03140	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
RE97_RS03150	COG0477	Major facilitator Superfamily
RE97_RS03165	COG3654	unkown
RE97_RS03185	COG4638	Rieske (2fe-2S)
RE97_RS03210	COG1028	Short-chain dehydrogenase reductase Sdr
RE97_RS03215	COG4638	Rieske (2fe-2S)
RE97_RS03225	COG2175	clavaminate synthase activity
RE97_RS03235	COG0148	phosphopyruvate hydratase activity
RE97_RS03270	COG2076	Multidrug Resistance protein
RE97_RS03280	COG1028	Short-chain dehydrogenase reductase Sdr
RE97_RS03305	COG1024	Enoyl-CoA hydratase
RE97_RS03310	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RE97_RS03315	COG0443	Heat shock 70 kDa protein
RE97_RS03320	COG1966	Carbon starvation protein
RE97_RS03325	COG1793	dna ligase
RE97_RS03335	COG1960	acyl-CoA dehydrogenase activity
RE97_RS03350	COG2186	Transcriptional regulator
RE97_RS03410	COG1309	transcriptional regulator
RE97_RS03415	COG2072	flavoprotein involved in K transport
RE97_RS03420	COG1309	transcriptional regulator
RE97_RS03425	COG2226	methyltransferase
RE97_RS03425	COG2867	negative regulation of translational initiation
RE97_RS03430	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
RE97_RS03450	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
RE97_RS03460	COG1119	ATPase activity
RE97_RS03470	COG1024	Enoyl-CoA hydratase
RE97_RS03495	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
RE97_RS03500	COG0110	maltose O-acetyltransferase activity
RE97_RS03505	COG0415	Belongs to the DNA photolyase family
RE97_RS03515	COG2409	Drug exporters of the RND superfamily
RE97_RS03520	COG1304	FMN binding
RE97_RS03570	COG0142	geranyltranstransferase activity
RE97_RS03635	COG0482	sulfurtransferase activity
RE97_RS03655	COG0626	cystathionine gamma-synthase activity
RE97_RS03695	COG0154	amidase activity
RE97_RS03700	COG0205	6-phosphofructokinase activity
RE97_RS03705	COG1192	Involved in chromosome partitioning
RE97_RS03720	COG2259	Doxx family
RE97_RS03745	COG0655	NAD(P)H dehydrogenase (quinone) activity
RE97_RS03760	COG0473	3-isopropylmalate dehydrogenase activity
RE97_RS03765	COG2271	Major facilitator Superfamily
RE97_RS03770	COG0179	Fumarylacetoacetate (FAA) hydrolase
RE97_RS03775	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
RE97_RS03800	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
RE97_RS03805	COG0066	3-isopropylmalate dehydratase activity
RE97_RS03820	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
RE97_RS03825	COG1920	GTP binding
RE97_RS03830	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
RE97_RS03835	COG1181	Belongs to the D-alanine--D-alanine ligase family
RE97_RS03850	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
RE97_RS03890	COG1461	Dihydroxyacetone kinase
RE97_RS03905	COG0656	L-ascorbic acid biosynthetic process
RE97_RS03910	COG0657	acetylesterase activity
RE97_RS03925	COG0742	ribosomal rna small subunit methyltransferase
RE97_RS03940	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
RE97_RS03945	COG0701	Predicted permease
RE97_RS03965	COG0571	ribonuclease III activity
RE97_RS03970	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
RE97_RS03975	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
RE97_RS03990	COG1196	nuclear chromosome segregation
RE97_RS04010	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
RE97_RS04045	COG1686	Belongs to the peptidase S11 family
RE97_RS04065	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
RE97_RS04070	COG0336	Belongs to the RNA methyltransferase TrmD family
RE97_RS04090	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
RE97_RS04110	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
RE97_RS04120	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
RE97_RS04170	COG0052	Belongs to the universal ribosomal protein uS2 family
RE97_RS04175	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
RE97_RS04180	COG0154	amidase activity
RE97_RS04195	COG1028	Short-chain dehydrogenase reductase Sdr
RE97_RS04210	COG0745	RESPONSE REGULATOR receiver
RE97_RS04220	COG0528	UMP kinase activity
RE97_RS04230	COG0575	Belongs to the CDS family
RE97_RS04235	COG0820	rRNA (adenine-C2-)-methyltransferase activity
RE97_RS04250	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
RE97_RS04255	COG0750	zinc metalloprotease
RE97_RS04260	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
RE97_RS04285	COG1492	cobalamin metabolic process
RE97_RS04300	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
RE97_RS04310	COG1028	Short-chain dehydrogenase reductase Sdr
RE97_RS04330	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
RE97_RS04345	COG0579	oxidoreductase
RE97_RS04370	COG1648	precorrin-2 dehydrogenase activity
RE97_RS04370	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
RE97_RS04385	COG0442	prolyl-tRNA aminoacylation
RE97_RS04400	COG0779	Required for maturation of 30S ribosomal subunits
RE97_RS04425	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
RE97_RS04435	COG1024	Enoyl-CoA hydratase
RE97_RS04460	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
RE97_RS04465	COG2977	Belongs to the P-Pant transferase superfamily
RE97_RS04470	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
RE97_RS04475	COG0183	Belongs to the thiolase family
RE97_RS04480	COG1960	acyl-CoA dehydrogenase activity
RE97_RS04500	COG1185	polyribonucleotide nucleotidyltransferase activity
RE97_RS04515	COG0686	Belongs to the AlaDH PNT family
RE97_RS04555	COG1403	HNH endonuclease
RE97_RS04565	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
RE97_RS04585	COG0318	PFAM AMP-dependent synthetase and ligase
RE97_RS04590	COG4770	biotin carboxylase activity
RE97_RS04600	COG1028	Short-chain dehydrogenase reductase Sdr
RE97_RS04615	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
RE97_RS04630	COG3214	Protein conserved in bacteria
RE97_RS04640	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RE97_RS04665	COG1674	ftsk spoiiie
RE97_RS04670	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
RE97_RS04685	COG1842	Phage shock protein A
RE97_RS04700	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
RE97_RS04735	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
RE97_RS04745	COG1196	nuclear chromosome segregation
RE97_RS04760	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
RE97_RS04765	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
RE97_RS04770	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
RE97_RS04785	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
RE97_RS04790	COG1388	LysM domain
RE97_RS04800	COG4044	May play a role in the intracellular transport of hydrophobic ligands
RE97_RS04885	COG0483	inositol monophosphate 1-phosphatase activity
RE97_RS04935	COG0569	domain protein
RE97_RS04940	COG0531	amino acid
RE97_RS04945	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
RE97_RS04950	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
RE97_RS04960	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
RE97_RS04980	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
RE97_RS05005	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
RE97_RS05070	COG1012	belongs to the aldehyde dehydrogenase family
RE97_RS05080	COG1028	Short-chain dehydrogenase reductase Sdr
RE97_RS05090	COG1309	transcriptional regulator
RE97_RS05120	COG4221	oxidoreductase activity
RE97_RS05250	COG4974	Belongs to the 'phage' integrase family
RE97_RS05290	COG1024	Enoyl-CoA hydratase
RE97_RS05305	COG1028	Short-chain dehydrogenase reductase Sdr
RE97_RS05310	COG0753	catalase activity
RE97_RS05320	COG1366	Belongs to the anti-sigma-factor antagonist family
RE97_RS05340	COG1414	Transcriptional regulator
RE97_RS05380	COG3485	protocatechuate 3,4-dioxygenase
RE97_RS05385	COG3485	protocatechuate 3,4-dioxygenase
RE97_RS05390	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
RE97_RS05435	COG4762	Protein conserved in bacteria
RE97_RS05440	COG0667	Aldo Keto reductase
RE97_RS05455	COG0025	NhaP-type Na H and K H
RE97_RS05460	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
RE97_RS05495	COG1946	Acyl-CoA thioesterase
RE97_RS05500	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
RE97_RS05510	COG1331	Highly conserved protein containing a thioredoxin domain
RE97_RS05540	COG0572	uridine kinase
RE97_RS05545	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
RE97_RS05555	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
RE97_RS05595	COG2272	Belongs to the type-B carboxylesterase lipase family
RE97_RS05610	COG1570	exodeoxyribonuclease VII activity
RE97_RS05620	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
RE97_RS05630	COG0012	GTP binding
RE97_RS05695	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
RE97_RS05725	COG0574	Belongs to the PEP-utilizing enzyme family
RE97_RS05725	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
RE97_RS05740	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
RE97_RS05755	COG1309	transcriptional regulator
RE97_RS05765	COG1960	acyl-CoA dehydrogenase activity
RE97_RS05770	COG1960	acyl-CoA dehydrogenase activity
RE97_RS05780	COG0714	Associated with various cellular activities
RE97_RS05795	COG1028	Short-chain dehydrogenase reductase Sdr
RE97_RS05800	COG2124	cytochrome p450
RE97_RS05810	COG0183	Belongs to the thiolase family
RE97_RS05815	COG1024	Enoyl-CoA hydratase
RE97_RS05835	COG0702	epimerase
RE97_RS05845	COG1024	Enoyl-CoA hydratase
RE97_RS05850	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RE97_RS05860	COG2409	Drug exporters of the RND superfamily
RE97_RS05870	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
RE97_RS05885	COG3467	pyridoxamine 5'-phosphate
RE97_RS05915	COG2154	pterin-4-alpha-carbinolamine dehydratase
RE97_RS05935	COG1140	nitrate reductase beta subunit
RE97_RS05950	COG1217	gtp-binding protein TYPA
RE97_RS05965	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
RE97_RS05975	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
RE97_RS05990	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
RE97_RS06000	COG0531	amino acid
RE97_RS06030	COG0529	Catalyzes the synthesis of activated sulfate
RE97_RS06035	COG2046	Belongs to the sulfate adenylyltransferase family
RE97_RS06045	COG0318	PFAM AMP-dependent synthetase and ligase
RE97_RS06060	COG1012	belongs to the aldehyde dehydrogenase family
RE97_RS06065	COG0506	proline dehydrogenase activity
RE97_RS06085	COG1960	acyl-CoA dehydrogenase activity
RE97_RS06100	COG1960	acyl-CoA dehydrogenase activity
RE97_RS06105	COG2124	cytochrome p450
RE97_RS06115	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RE97_RS06125	COG0318	PFAM AMP-dependent synthetase and ligase
RE97_RS06130	COG0477	Major facilitator Superfamily
RE97_RS06165	COG1611	Belongs to the LOG family
RE97_RS06170	COG0318	PFAM AMP-dependent synthetase and ligase
RE97_RS06180	COG0463	Glycosyl transferase, family 2
RE97_RS06190	COG0519	Catalyzes the synthesis of GMP from XMP
RE97_RS06210	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
RE97_RS06225	COG3559	Exporter of polyketide antibiotics
RE97_RS06230	COG1131	(ABC) transporter
RE97_RS06235	COG1309	transcriptional regulator
RE97_RS06240	COG4122	O-methyltransferase activity
RE97_RS06250	COG5662	AntiSigma factor
RE97_RS06255	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RE97_RS06260	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
RE97_RS06280	COG2239	Acts as a magnesium transporter
RE97_RS06325	COG0598	Magnesium transport protein CorA
RE97_RS06330	COG0039	L-malate dehydrogenase activity
RE97_RS06355	COG0567	Dehydrogenase, E1 component
RE97_RS06355	COG0508	dehydrogenase complex catalyzes the overall conversion of
RE97_RS06385	COG1028	Short-chain dehydrogenase reductase Sdr
RE97_RS06395	COG1028	Short-chain dehydrogenase reductase Sdr
RE97_RS06405	COG1028	Short-chain dehydrogenase reductase Sdr
RE97_RS06455	COG0277	FAD linked oxidase domain protein
RE97_RS06475	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RE97_RS06555	COG1403	HNH endonuclease
RE97_RS06645	COG3631	Ketosteroid isomerase-related protein
RE97_RS06650	COG0494	nUDIX hydrolase
RE97_RS06685	COG0018	arginyl-trna synthetase
RE97_RS06695	COG0460	homoserine dehydrogenase
RE97_RS06705	COG0083	homoserine kinase activity
RE97_RS06725	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
RE97_RS06730	COG2890	protein-(glutamine-N5) methyltransferase activity
RE97_RS06750	COG0356	it plays a direct role in the translocation of protons across the membrane
RE97_RS06755	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
RE97_RS06765	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
RE97_RS06765	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
RE97_RS06780	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
RE97_RS06800	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
RE97_RS06825	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
RE97_RS06840	COG0583	DNA-binding transcription factor activity
RE97_RS06845	COG2814	Major facilitator Superfamily
RE97_RS06870	COG0346	lactoylglutathione lyase activity
RE97_RS06885	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
RE97_RS06895	COG0058	SHG alpha-glucan phosphorylase activity
RE97_RS06905	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
RE97_RS06930	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
RE97_RS06935	COG1234	tRNA 3'-trailer cleavage
RE97_RS06940	COG2123	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
RE97_RS06950	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
RE97_RS07005	COG1028	Short-chain dehydrogenase reductase Sdr
RE97_RS07010	COG1960	acyl-CoA dehydrogenase activity
RE97_RS07020	COG0183	Belongs to the thiolase family
RE97_RS07025	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RE97_RS07030	COG1960	acyl-CoA dehydrogenase activity
RE97_RS07035	COG1802	Transcriptional regulator
RE97_RS07045	COG0318	PFAM AMP-dependent synthetase and ligase
RE97_RS07060	COG1024	Enoyl-CoA hydratase
RE97_RS07065	COG1024	Enoyl-CoA hydratase
RE97_RS07070	COG1024	Enoyl-CoA hydratase
RE97_RS07090	COG1028	Short-chain dehydrogenase reductase Sdr
RE97_RS07105	COG1024	Enoyl-CoA hydratase
RE97_RS07130	COG1960	acyl-CoA dehydrogenase activity
RE97_RS07135	COG0183	Belongs to the thiolase family
RE97_RS07145	COG2124	cytochrome p450
RE97_RS07170	COG4638	Rieske (2fe-2S)
RE97_RS07175	COG2072	flavoprotein involved in K transport
RE97_RS07195	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
RE97_RS07210	COG1309	transcriptional regulator
RE97_RS07245	COG2124	cytochrome p450
RE97_RS07250	COG0657	acetylesterase activity
RE97_RS07255	COG1960	acyl-CoA dehydrogenase activity
RE97_RS07260	COG1960	acyl-CoA dehydrogenase activity
RE97_RS07275	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
RE97_RS07300	COG1960	acyl-CoA dehydrogenase activity
RE97_RS07305	COG1960	acyl-CoA dehydrogenase activity
RE97_RS07310	COG1960	acyl-CoA dehydrogenase activity
RE97_RS07315	COG1960	acyl-CoA dehydrogenase activity
RE97_RS07345	COG2124	cytochrome p450
RE97_RS07395	COG3757	hydrolase, family 25
RE97_RS07405	COG0736	holo-[acyl-carrier-protein] synthase activity
RE97_RS07410	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
RE97_RS07440	COG4552	Acetyltransferase involved in intracellular survival and related
RE97_RS07445	COG2409	Drug exporters of the RND superfamily
RE97_RS07455	COG1376	ErfK ybiS ycfS ynhG family protein
RE97_RS07470	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
RE97_RS07475	COG0433	COG0433 Predicted ATPase
RE97_RS07480	COG0300	oxidoreductase activity
RE97_RS07500	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
RE97_RS07510	COG1960	acyl-CoA dehydrogenase activity
RE97_RS07515	COG2030	dehydratase
RE97_RS07535	COG0508	dehydrogenase complex catalyzes the overall conversion of
RE97_RS07570	COG0657	acetylesterase activity
RE97_RS07585	COG2937	Belongs to the GPAT DAPAT family
RE97_RS07595	COG0629	single-stranded DNA binding
RE97_RS07605	COG2902	Dehydrogenase
RE97_RS07625	COG0366	Alpha amylase catalytic
RE97_RS07630	COG2346	COG2346, Truncated hemoglobins
RE97_RS07655	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
RE97_RS07660	COG0698	ribose 5-phosphate isomerase
RE97_RS07670	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
RE97_RS07690	COG0740	serine-type endopeptidase activity
RE97_RS07695	COG0740	serine-type endopeptidase activity
RE97_RS07700	COG2040	homocysteine
RE97_RS07710	COG0674	pyruvate-flavodoxin oxidoreductase activity
RE97_RS07710	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
RE97_RS07715	COG1013	pyruvate-flavodoxin oxidoreductase activity
RE97_RS07720	COG0746	molybdenum cofactor guanylyltransferase activity
RE97_RS07725	COG1388	LysM domain
RE97_RS07730	COG3268	Saccharopine dehydrogenase
RE97_RS07735	COG0525	valine-tRNA ligase activity
RE97_RS07740	COG0285	dihydrofolate synthase activity
RE97_RS07750	COG0105	UTP biosynthetic process
RE97_RS07755	COG1530	ribonuclease E activity
RE97_RS07770	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
RE97_RS07775	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
RE97_RS07810	COG0066	3-isopropylmalate dehydratase activity
RE97_RS07815	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
RE97_RS07830	COG2188	Transcriptional regulator
RE97_RS07835	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RE97_RS07840	COG5002	protein histidine kinase activity
RE97_RS07855	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
RE97_RS07860	COG0542	response to heat
RE97_RS07870	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
RE97_RS07875	COG0799	negative regulation of ribosome biogenesis
RE97_RS07885	COG2755	lipolytic protein G-D-S-L family
RE97_RS07915	COG0318	PFAM AMP-dependent synthetase and ligase
RE97_RS07920	COG5651	PPE family
RE97_RS07950	COG1960	acyl-CoA dehydrogenase activity
RE97_RS07955	COG1960	acyl-CoA dehydrogenase activity
RE97_RS07960	COG1596	polysaccharide export
RE97_RS07960	COG1555	photosystem II stabilization
RE97_RS07965	COG0658	competence protein
RE97_RS07965	COG2333	competence protein COMEC
RE97_RS07980	COG2308	Evidence 4 Homologs of previously reported genes of
RE97_RS08000	COG1234	tRNA 3'-trailer cleavage
RE97_RS08015	COG0481	GTPase activity
RE97_RS08025	COG3387	PFAM Glycoside hydrolase 15-related
RE97_RS08035	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
RE97_RS08040	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
RE97_RS08045	COG4208	sulfate ABC transporter
RE97_RS08050	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
RE97_RS08060	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
RE97_RS08075	COG1169	isochorismate synthase
RE97_RS08100	COG2072	flavoprotein involved in K transport
RE97_RS08110	COG0300	oxidoreductase activity
RE97_RS08115	COG0657	acetylesterase activity
RE97_RS08140	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
RE97_RS08165	COG0318	PFAM AMP-dependent synthetase and ligase
RE97_RS08170	COG1012	belongs to the aldehyde dehydrogenase family
RE97_RS08175	COG1012	belongs to the aldehyde dehydrogenase family
RE97_RS08200	COG1309	transcriptional regulator
RE97_RS08215	COG1021	2,3-dihydroxybenzoate-AMP ligase
RE97_RS08220	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RE97_RS08235	COG0604	alcohol dehydrogenase
RE97_RS08235	COG3321	synthase
RE97_RS08250	COG3486	L-lysine 6-monooxygenase (NADPH) activity
RE97_RS08270	COG1595	DNA-templated transcription, initiation
RE97_RS08285	COG1420	regulation of RNA biosynthetic process
RE97_RS08290	COG0484	heat shock protein binding
RE97_RS08305	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
RE97_RS08335	COG2801	Transposase and inactivated derivatives
RE97_RS08340	COG2963	transposase activity
RE97_RS08355	COG3328	transposase activity
RE97_RS08385	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
RE97_RS08390	COG1982	Orn Lys Arg decarboxylase major
RE97_RS08400	COG1381	Involved in DNA repair and RecF pathway recombination
RE97_RS08425	COG0423	glycine-tRNA ligase activity
RE97_RS08475	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RE97_RS08480	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RE97_RS08490	COG1045	serine acetyltransferase
RE97_RS08510	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
RE97_RS08515	COG2855	membrane
RE97_RS08520	COG4424	Sulfotransferase
RE97_RS08525	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
RE97_RS08530	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
RE97_RS08555	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
RE97_RS08590	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
RE97_RS08595	COG0243	molybdopterin cofactor binding
RE97_RS08605	COG2223	nitrite transmembrane transporter activity
RE97_RS08615	COG1716	ATPase activity
RE97_RS08615	COG1131	(ABC) transporter
RE97_RS08615	COG0842	Transport permease protein
RE97_RS08635	COG1522	sequence-specific DNA binding
RE97_RS08640	COG1834	amidinotransferase
RE97_RS08645	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
RE97_RS08650	COG0531	amino acid
RE97_RS08660	COG0395	ABC-type sugar transport system, permease component
RE97_RS08665	COG1175	transmembrane transport
RE97_RS08710	COG1012	belongs to the aldehyde dehydrogenase family
RE97_RS08720	COG0563	adenylate kinase activity
RE97_RS08725	COG2814	Major facilitator Superfamily
RE97_RS08735	COG3629	intracellular signal transduction
RE97_RS08735	COG3903	Transcriptional regulator
RE97_RS08750	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
RE97_RS08755	COG2226	methyltransferase
RE97_RS08780	COG0326	Molecular chaperone. Has ATPase activity
RE97_RS08800	COG2239	Acts as a magnesium transporter
RE97_RS08815	COG0697	spore germination
RE97_RS08840	COG0596	Alpha beta hydrolase
RE97_RS08850	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
RE97_RS08855	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RE97_RS08870	COG2124	cytochrome p450
RE97_RS08875	COG3547	Transposase (IS116 IS110 IS902 family)
RE97_RS08900	COG0438	transferase activity, transferring glycosyl groups
RE97_RS08905	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
RE97_RS08920	COG0657	acetylesterase activity
RE97_RS08930	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
RE97_RS08950	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
RE97_RS08990	COG1487	ribonuclease activity
RE97_RS09015	COG0860	N-Acetylmuramoyl-L-alanine amidase
RE97_RS09030	COG2072	flavoprotein involved in K transport
RE97_RS09090	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
RE97_RS09120	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RE97_RS09140	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
RE97_RS09185	COG0596	Alpha beta hydrolase
RE97_RS09280	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
RE97_RS09305	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
RE97_RS09335	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
RE97_RS09340	COG0321	lipoyl(octanoyl) transferase activity
RE97_RS09370	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
RE97_RS09380	COG0404	The glycine cleavage system catalyzes the degradation of glycine
RE97_RS09385	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
RE97_RS09390	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
RE97_RS09395	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
RE97_RS09425	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RE97_RS09435	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
RE97_RS09475	COG1845	cytochrome c oxidase, subunit III
RE97_RS09500	COG1022	Amp-dependent synthetase and ligase
RE97_RS09515	COG0003	Pfam Anion-transporting ATPase
RE97_RS09545	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
RE97_RS09550	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RE97_RS09570	COG0142	geranyltranstransferase activity
RE97_RS09600	COG0275	rRNA processing
RE97_RS09610	COG0768	penicillin binding
RE97_RS09615	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
RE97_RS09625	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
RE97_RS09630	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
RE97_RS09640	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
RE97_RS09645	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
RE97_RS09655	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
RE97_RS09670	COG1799	cell septum assembly
RE97_RS09705	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
RE97_RS09715	COG1403	HNH endonuclease
RE97_RS09720	COG0167	dihydroorotate dehydrogenase activity
RE97_RS09755	COG1218	3'(2'),5'-bisphosphate nucleotidase
RE97_RS09760	COG0215	cysteine-tRNA ligase activity
RE97_RS09775	COG0028	Belongs to the TPP enzyme family
RE97_RS09800	COG3321	synthase
RE97_RS09800	COG0604	alcohol dehydrogenase
RE97_RS09800	COG1028	Short-chain dehydrogenase reductase Sdr
RE97_RS09825	COG1028	Short-chain dehydrogenase reductase Sdr
RE97_RS09835	COG1410	methionine synthase
RE97_RS09835	COG0646	methionine synthase
RE97_RS09880	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
RE97_RS09895	COG0140	phosphoribosyl-ATP diphosphatase activity
RE97_RS09955	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
RE97_RS09975	COG2378	regulation of single-species biofilm formation
RE97_RS10070	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RE97_RS10100	COG0412	Dienelactone hydrolase
RE97_RS10110	COG1574	metal-dependent hydrolase with the TIM-barrel fold
RE97_RS10135	COG0604	alcohol dehydrogenase
RE97_RS10135	COG3321	synthase
RE97_RS10140	COG3321	synthase
RE97_RS10140	COG0604	alcohol dehydrogenase
RE97_RS10145	COG3321	synthase
RE97_RS10145	COG0604	alcohol dehydrogenase
RE97_RS10175	COG0714	Associated with various cellular activities
RE97_RS10230	COG2272	Belongs to the type-B carboxylesterase lipase family
RE97_RS10240	COG3265	gluconokinase activity
RE97_RS10260	COG1335	isochorismatase
RE97_RS10280	COG1595	DNA-templated transcription, initiation
RE97_RS10290	COG1175	transmembrane transport
RE97_RS10295	COG0395	ABC-type sugar transport system, permease component
RE97_RS10300	COG3842	ATPase activity
RE97_RS10305	COG1752	Esterase of the alpha-beta hydrolase superfamily
RE97_RS10330	COG2837	iron assimilation
RE97_RS10370	COG0667	Aldo Keto reductase
RE97_RS10375	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
RE97_RS10390	COG1960	acyl-CoA dehydrogenase activity
RE97_RS10455	COG0657	acetylesterase activity
RE97_RS10480	COG1946	Acyl-CoA thioesterase
RE97_RS10505	COG0753	catalase activity
RE97_RS10555	COG1028	Short-chain dehydrogenase reductase Sdr
RE97_RS10565	COG0183	Belongs to the thiolase family
RE97_RS10570	COG1960	acyl-CoA dehydrogenase activity
RE97_RS10580	COG1309	transcriptional regulator
RE97_RS10585	COG2267	carboxylic ester hydrolase activity
RE97_RS10600	COG1028	Short-chain dehydrogenase reductase Sdr
RE97_RS10645	COG0301	tRNA thio-modification
RE97_RS10655	COG0789	Transcriptional regulator
RE97_RS10665	COG0484	heat shock protein binding
RE97_RS10675	COG0545	Peptidyl-prolyl cis-trans isomerase
RE97_RS10680	COG1028	Short-chain dehydrogenase reductase Sdr
RE97_RS10700	COG2301	Belongs to the HpcH HpaI aldolase family
RE97_RS10710	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
RE97_RS10725	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RE97_RS10730	COG1643	Atp-dependent helicase
RE97_RS10745	COG1024	Enoyl-CoA hydratase
RE97_RS10790	COG0723	plastoquinol--plastocyanin reductase activity
RE97_RS10800	COG1376	ErfK ybiS ycfS ynhG family protein
RE97_RS10810	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
RE97_RS10815	COG3757	hydrolase, family 25
RE97_RS10820	COG0438	transferase activity, transferring glycosyl groups
RE97_RS10825	COG2226	methyltransferase
RE97_RS10850	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
RE97_RS10865	COG1012	belongs to the aldehyde dehydrogenase family
RE97_RS10895	COG4977	sequence-specific DNA binding
RE97_RS10950	COG0640	Transcriptional regulator
RE97_RS10970	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
RE97_RS11015	COG1950	PFAM Membrane protein of
RE97_RS11025	COG2814	Major facilitator Superfamily
RE97_RS11030	COG1058	Belongs to the CinA family
RE97_RS11030	COG1546	Belongs to the CinA family
RE97_RS11040	COG1490	D-aminoacyl-tRNA deacylase activity
RE97_RS11045	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
RE97_RS11050	COG1063	alcohol dehydrogenase
RE97_RS11060	COG1403	HNH endonuclease
RE97_RS11065	COG2070	2-Nitropropane dioxygenase
RE97_RS11115	COG1652	LysM domain
RE97_RS11155	COG0174	glutamine synthetase
RE97_RS11165	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
RE97_RS11175	COG2193	ferroxidase activity
RE97_RS11185	COG1024	Enoyl-CoA hydratase
RE97_RS11210	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
RE97_RS11265	COG0183	Belongs to the thiolase family
RE97_RS11270	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RE97_RS11275	COG1968	undecaprenyl-diphosphatase activity
RE97_RS11280	COG4221	oxidoreductase activity
RE97_RS11285	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
RE97_RS11335	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RE97_RS11345	COG1252	NADH dehydrogenase
RE97_RS11365	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
RE97_RS11375	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
RE97_RS11380	COG0318	PFAM AMP-dependent synthetase and ligase
RE97_RS11385	COG1960	acyl-CoA dehydrogenase activity
RE97_RS11390	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RE97_RS11395	COG1253	flavin adenine dinucleotide binding
RE97_RS11400	COG1253	flavin adenine dinucleotide binding
RE97_RS11405	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
RE97_RS11425	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
RE97_RS11425	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
RE97_RS11475	COG0653	protein targeting
RE97_RS11490	COG1053	succinate dehydrogenase
RE97_RS11520	COG1285	pathogenesis
RE97_RS11530	COG5651	PPE family
RE97_RS11575	COG0657	acetylesterase activity
RE97_RS11590	COG1404	Belongs to the peptidase S8 family
RE97_RS11615	COG5651	PPE family
RE97_RS11625	COG5651	PPE family
RE97_RS11665	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
RE97_RS11700	COG1028	Short-chain dehydrogenase reductase Sdr
RE97_RS11705	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
RE97_RS11710	COG0022	dehydrogenase e1 component
RE97_RS11720	COG1024	Enoyl-CoA hydratase
RE97_RS11740	COG1053	succinate dehydrogenase
RE97_RS11750	COG0513	Belongs to the DEAD box helicase family
RE97_RS11755	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
RE97_RS11815	COG4221	oxidoreductase activity
RE97_RS11835	COG0318	PFAM AMP-dependent synthetase and ligase
RE97_RS11840	COG2072	flavoprotein involved in K transport
RE97_RS11865	COG1960	acyl-CoA dehydrogenase activity
RE97_RS11870	COG1960	acyl-CoA dehydrogenase activity
RE97_RS11875	COG1716	ATPase activity
RE97_RS11875	COG0842	Transport permease protein
RE97_RS11875	COG1131	(ABC) transporter
RE97_RS11880	COG0657	acetylesterase activity
RE97_RS11885	COG1028	Short-chain dehydrogenase reductase Sdr
RE97_RS11900	COG2267	carboxylic ester hydrolase activity
RE97_RS11910	COG2072	flavoprotein involved in K transport
RE97_RS11925	COG0346	lactoylglutathione lyase activity
RE97_RS11940	COG0657	acetylesterase activity
RE97_RS11955	COG1028	Short-chain dehydrogenase reductase Sdr
RE97_RS11960	COG2072	flavoprotein involved in K transport
RE97_RS11975	COG0657	acetylesterase activity
RE97_RS11985	COG1028	Short-chain dehydrogenase reductase Sdr
RE97_RS11990	COG1028	Short-chain dehydrogenase reductase Sdr
RE97_RS12005	COG1053	succinate dehydrogenase
RE97_RS12010	COG1403	HNH endonuclease
RE97_RS12040	COG2132	Multicopper oxidase
RE97_RS12060	COG2271	Major facilitator Superfamily
RE97_RS12065	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
RE97_RS12065	COG0189	ligase activity
RE97_RS12105	COG1160	GTP binding
RE97_RS12110	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
RE97_RS12120	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
RE97_RS12145	COG0494	nUDIX hydrolase
RE97_RS12170	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
RE97_RS12185	COG0647	UMP catabolic process
RE97_RS12200	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
RE97_RS12205	COG2094	Belongs to the DNA glycosylase MPG family
RE97_RS12215	COG1131	(ABC) transporter
RE97_RS12225	COG1309	transcriptional regulator
RE97_RS12230	COG2835	tetraacyldisaccharide 4'-kinase activity
RE97_RS12270	COG4948	Mandelate Racemase Muconate Lactonizing
RE97_RS12275	COG1028	Short-chain dehydrogenase reductase Sdr
RE97_RS12280	COG1028	Short-chain dehydrogenase reductase Sdr
RE97_RS12300	COG0583	DNA-binding transcription factor activity
RE97_RS12305	COG3707	response regulator
RE97_RS12310	COG0488	(ABC) transporter
RE97_RS12325	COG3321	synthase
RE97_RS12325	COG3321	synthase
RE97_RS12325	COG0604	alcohol dehydrogenase
RE97_RS12325	COG0604	alcohol dehydrogenase
RE97_RS12330	COG3321	synthase
RE97_RS12330	COG0604	alcohol dehydrogenase
RE97_RS12340	COG0165	Argininosuccinate lyase
RE97_RS12345	COG0137	argininosuccinate synthase activity
RE97_RS12350	COG1438	arginine binding
RE97_RS12355	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
RE97_RS12365	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
RE97_RS12370	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
RE97_RS12375	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
RE97_RS12380	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RE97_RS12380	COG0072	phenylalanine-tRNA ligase activity
RE97_RS12385	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
RE97_RS12440	COG1309	transcriptional regulator
RE97_RS12495	COG1285	pathogenesis
RE97_RS12535	COG1716	ATPase activity
RE97_RS12535	COG0842	Transport permease protein
RE97_RS12535	COG1131	(ABC) transporter
RE97_RS12550	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
RE97_RS12560	COG0237	dephospho-CoA kinase activity
RE97_RS12560	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
RE97_RS12570	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
RE97_RS12590	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
RE97_RS12615	COG1271	oxidase subunit
RE97_RS12620	COG1294	oxidase, subunit
RE97_RS12625	COG4988	ABC transporter
RE97_RS12630	COG1132	(ABC) transporter
RE97_RS12640	COG1946	Acyl-CoA thioesterase
RE97_RS12660	COG0159	tryptophan synthase activity
RE97_RS12690	COG0387	Pfam Sodium calcium exchanger
RE97_RS12695	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
RE97_RS12700	COG0107	imidazoleglycerol-phosphate synthase activity
RE97_RS12705	COG0483	inositol monophosphate 1-phosphatase activity
RE97_RS12710	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
RE97_RS12715	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
RE97_RS12725	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
RE97_RS12730	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
RE97_RS12740	COG0157	Belongs to the NadC ModD family
RE97_RS12750	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
RE97_RS12760	COG3547	Transposase (IS116 IS110 IS902 family)
RE97_RS12780	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
RE97_RS12805	COG5002	protein histidine kinase activity
RE97_RS12825	COG0156	8-amino-7-oxononanoate synthase activity
RE97_RS12830	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
RE97_RS12840	COG0791	NLP P60 protein
RE97_RS12840	COG3883	PFAM NLP P60 protein
RE97_RS12925	COG0300	oxidoreductase activity
RE97_RS12935	COG2346	COG2346, Truncated hemoglobins
RE97_RS12955	COG0252	asparaginase activity
RE97_RS12970	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
RE97_RS12980	COG2070	2-Nitropropane dioxygenase
RE97_RS13035	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RE97_RS13040	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
RE97_RS13055	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
RE97_RS13085	COG5002	protein histidine kinase activity
RE97_RS13090	COG0745	RESPONSE REGULATOR receiver
RE97_RS13135	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
RE97_RS13155	COG2304	oxidoreductase activity
RE97_RS13165	COG0714	Associated with various cellular activities
RE97_RS13175	COG3883	PFAM NLP P60 protein
RE97_RS13175	COG0791	NLP P60 protein
RE97_RS13190	COG1309	transcriptional regulator
RE97_RS13200	COG0488	(ABC) transporter
RE97_RS13210	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RE97_RS13215	COG1960	acyl-CoA dehydrogenase activity
RE97_RS13235	COG2151	metal-sulfur cluster biosynthetic enzyme
RE97_RS13250	COG0396	ATPase activity
RE97_RS13300	COG0109	protoheme IX farnesyltransferase activity
RE97_RS13310	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
RE97_RS13335	COG0123	including yeast histone deacetylase and acetoin utilization protein
RE97_RS13340	COG0667	Aldo Keto reductase
RE97_RS13350	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
RE97_RS13365	COG0149	triose-phosphate isomerase activity
RE97_RS13400	COG0318	PFAM AMP-dependent synthetase and ligase
RE97_RS13405	COG0657	acetylesterase activity
RE97_RS13450	COG1660	Displays ATPase and GTPase activities
RE97_RS13455	COG0322	excinuclease ABC activity
RE97_RS13480	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
RE97_RS13485	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
RE97_RS13485	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
RE97_RS13520	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
RE97_RS13545	COG0657	acetylesterase activity
RE97_RS13550	COG2072	flavoprotein involved in K transport
RE97_RS13555	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
RE97_RS13565	COG1758	RNA polymerase activity
RE97_RS13570	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
RE97_RS13595	COG0505	Belongs to the CarA family
RE97_RS13615	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
RE97_RS13625	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RE97_RS13630	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
RE97_RS13655	COG2188	Transcriptional regulator
RE97_RS13670	COG0745	RESPONSE REGULATOR receiver
RE97_RS13675	COG2205	protein histidine kinase activity
RE97_RS13705	COG0006	proline dipeptidase activity
RE97_RS13715	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
RE97_RS13720	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
RE97_RS13730	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
RE97_RS13740	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RE97_RS13765	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RE97_RS13770	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RE97_RS13780	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
RE97_RS13785	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
RE97_RS13790	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
RE97_RS13800	COG0432	Pfam Uncharacterised protein family UPF0047
RE97_RS13870	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
RE97_RS13890	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RE97_RS13895	COG0235	Class ii aldolase
RE97_RS13900	COG1396	sequence-specific DNA binding
RE97_RS13925	COG1403	HNH endonuclease
RE97_RS13930	COG0124	histidyl-tRNA synthetase
RE97_RS13935	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RE97_RS13950	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
RE97_RS13955	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
RE97_RS13960	COG0747	negative chemotaxis
RE97_RS13965	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
RE97_RS13970	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
RE97_RS13985	COG1022	Amp-dependent synthetase and ligase
RE97_RS13985	COG3320	Male sterility
RE97_RS14030	COG3766	membrane
RE97_RS14040	COG0217	transcriptional regulatory protein
RE97_RS14075	COG0657	acetylesterase activity
RE97_RS14080	COG2755	lipolytic protein G-D-S-L family
RE97_RS14095	COG1024	Enoyl-CoA hydratase
RE97_RS14135	COG0121	glutamine amidotransferase
RE97_RS14145	COG0318	PFAM AMP-dependent synthetase and ligase
RE97_RS14150	COG3391	amine dehydrogenase activity
RE97_RS14200	COG0745	RESPONSE REGULATOR receiver
RE97_RS14205	COG2205	protein histidine kinase activity
RE97_RS14220	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
RE97_RS14230	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
RE97_RS14275	COG3956	TIGRFAM MazG family protein
RE97_RS14300	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
RE97_RS14310	COG1393	Belongs to the ArsC family
RE97_RS14325	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
RE97_RS14330	COG0193	aminoacyl-tRNA hydrolase activity
RE97_RS14335	COG0318	PFAM AMP-dependent synthetase and ligase
RE97_RS14345	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
RE97_RS14355	COG0084	hydrolase, TatD family'
RE97_RS14400	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
RE97_RS14415	COG0297	glycogen (starch) synthase activity
RE97_RS14455	COG0438	transferase activity, transferring glycosyl groups
RE97_RS14455	COG0297	glycogen (starch) synthase activity
RE97_RS14500	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
RE97_RS14535	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RE97_RS14535	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
RE97_RS14540	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
RE97_RS14545	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
RE97_RS14560	COG4638	Rieske (2fe-2S)
RE97_RS14605	COG1210	Utp--glucose-1-phosphate uridylyltransferase
RE97_RS14610	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
RE97_RS14625	COG1970	mechanosensitive ion channel activity
RE97_RS14630	COG0521	Mo-molybdopterin cofactor biosynthetic process
RE97_RS14630	COG0315	cyclic pyranopterin monophosphate synthase activity
RE97_RS14635	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RE97_RS14640	COG2205	protein histidine kinase activity
RE97_RS14660	COG1960	acyl-CoA dehydrogenase activity
RE97_RS14665	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
RE97_RS14680	COG1024	Enoyl-CoA hydratase
RE97_RS14710	COG0138	bifunctional purine biosynthesis protein purh
RE97_RS14750	COG4942	peptidase
RE97_RS14770	COG0166	Belongs to the GPI family
RE97_RS14780	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
RE97_RS14815	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
RE97_RS14835	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
RE97_RS14840	COG0246	Mannitol dehydrogenase
RE97_RS14890	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RE97_RS15040	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RE97_RS15050	COG0438	transferase activity, transferring glycosyl groups
RE97_RS15060	COG0745	RESPONSE REGULATOR receiver
RE97_RS15085	COG0259	pyridoxamine-phosphate oxidase activity
RE97_RS15110	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
RE97_RS15150	COG2814	Major facilitator Superfamily
RE97_RS15165	COG0435	Glutathione S-transferase
RE97_RS15175	COG1278	Cold shock
RE97_RS15180	COG3304	Inner membrane component domain
RE97_RS15205	COG0521	Mo-molybdopterin cofactor biosynthetic process
RE97_RS15225	COG1061	Type III restriction enzyme res subunit
RE97_RS15230	COG0183	Belongs to the thiolase family
RE97_RS15245	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RE97_RS15270	COG1250	3-hydroxyacyl-CoA dehydrogenase
RE97_RS15270	COG1024	Enoyl-CoA hydratase
RE97_RS15275	COG0183	Belongs to the thiolase family
RE97_RS15295	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RE97_RS15305	COG3961	Belongs to the TPP enzyme family
RE97_RS15320	COG0318	PFAM AMP-dependent synthetase and ligase
RE97_RS15335	COG1024	Enoyl-CoA hydratase
RE97_RS15345	COG1309	transcriptional regulator
RE97_RS15375	COG1309	transcriptional regulator
RE97_RS15405	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
RE97_RS15430	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
RE97_RS15435	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
RE97_RS15440	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RE97_RS15485	COG1960	acyl-CoA dehydrogenase activity
RE97_RS15490	COG1960	acyl-CoA dehydrogenase activity
RE97_RS15495	COG0778	Nitroreductase
RE97_RS15495	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
RE97_RS15535	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
RE97_RS15575	COG2124	cytochrome p450
RE97_RS15595	COG2124	cytochrome p450
RE97_RS15605	COG1309	transcriptional regulator
RE97_RS15610	COG0183	Belongs to the thiolase family
RE97_RS15630	COG4638	Rieske (2fe-2S)
RE97_RS15640	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
RE97_RS15650	COG1960	acyl-CoA dehydrogenase activity
RE97_RS15665	COG1960	acyl-CoA dehydrogenase activity
RE97_RS15675	COG1028	Short-chain dehydrogenase reductase Sdr
RE97_RS15685	COG1028	Short-chain dehydrogenase reductase Sdr
RE97_RS15690	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RE97_RS15730	COG2132	Multicopper oxidase
RE97_RS15745	COG1028	Short-chain dehydrogenase reductase Sdr
RE97_RS15755	COG1053	succinate dehydrogenase
RE97_RS15760	COG3384	dioxygenase
RE97_RS15765	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RE97_RS15770	COG2267	carboxylic ester hydrolase activity
RE97_RS15780	COG1053	succinate dehydrogenase
RE97_RS15785	COG4585	Histidine kinase
RE97_RS15795	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
RE97_RS15805	COG0183	Belongs to the thiolase family
RE97_RS15810	COG3479	Phenolic acid decarboxylase
RE97_RS15815	COG0596	Alpha beta hydrolase
RE97_RS15825	COG1960	acyl-CoA dehydrogenase activity
RE97_RS15830	COG1960	acyl-CoA dehydrogenase activity
RE97_RS15840	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
RE97_RS15855	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RE97_RS15860	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RE97_RS15865	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
RE97_RS15870	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
RE97_RS15870	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
RE97_RS15895	COG2124	cytochrome p450
RE97_RS15910	COG1028	Short-chain dehydrogenase reductase Sdr
RE97_RS15940	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
RE97_RS15945	COG0590	tRNA wobble adenosine to inosine editing
RE97_RS15950	COG0640	Transcriptional regulator
RE97_RS15990	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
RE97_RS16010	COG0456	acetyltransferase
RE97_RS16010	COG0454	-acetyltransferase
RE97_RS16015	COG0745	RESPONSE REGULATOR receiver
RE97_RS16025	COG3118	belongs to the thioredoxin family
RE97_RS16050	COG4044	May play a role in the intracellular transport of hydrophobic ligands
RE97_RS16060	COG0404	The glycine cleavage system catalyzes the degradation of glycine
RE97_RS16070	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
RE97_RS16090	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
RE97_RS16110	COG2837	iron assimilation
RE97_RS16135	COG0047	phosphoribosylformylglycinamidine synthase activity
RE97_RS16140	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
RE97_RS16150	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
RE97_RS16165	COG0477	Major facilitator Superfamily
RE97_RS16170	COG0477	Major facilitator Superfamily
RE97_RS16190	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
RE97_RS16205	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
RE97_RS16265	COG4221	oxidoreductase activity
RE97_RS16270	COG2124	cytochrome p450
RE97_RS16300	COG2205	protein histidine kinase activity
RE97_RS16305	COG0745	RESPONSE REGULATOR receiver
RE97_RS16360	COG0154	amidase activity
RE97_RS16370	COG1316	TRANSCRIPTIONal
RE97_RS16385	COG1024	Enoyl-CoA hydratase
RE97_RS16390	COG0390	transport system, permease component
RE97_RS16395	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
RE97_RS16400	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
RE97_RS16425	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
RE97_RS16450	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
RE97_RS16460	COG1028	Short-chain dehydrogenase reductase Sdr
RE97_RS16470	COG1960	acyl-CoA dehydrogenase activity
RE97_RS16480	COG0318	PFAM AMP-dependent synthetase and ligase
RE97_RS16495	COG0028	Belongs to the TPP enzyme family
RE97_RS16505	COG3001	Fructosamine kinase
RE97_RS16515	COG1024	Enoyl-CoA hydratase
RE97_RS16525	COG2124	cytochrome p450
RE97_RS16535	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RE97_RS16550	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
RE97_RS16565	COG4638	Rieske (2fe-2S)
RE97_RS16595	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
RE97_RS16600	COG4569	acetaldehyde dehydrogenase (acetylating) activity
RE97_RS16605	COG3971	2-oxopent-4-enoate hydratase activity
RE97_RS16610	COG1053	succinate dehydrogenase
RE97_RS16615	COG2030	dehydratase
RE97_RS16635	COG2030	dehydratase
RE97_RS16640	COG1960	acyl-CoA dehydrogenase activity
RE97_RS16645	COG1960	acyl-CoA dehydrogenase activity
RE97_RS16650	COG2124	cytochrome p450
RE97_RS16655	COG0183	Belongs to the thiolase family
RE97_RS16670	COG1028	Short-chain dehydrogenase reductase Sdr
RE97_RS16675	COG1028	Short-chain dehydrogenase reductase Sdr
RE97_RS16680	COG1024	Enoyl-CoA hydratase
RE97_RS16710	COG0183	Belongs to the thiolase family
RE97_RS16720	COG1028	Short-chain dehydrogenase reductase Sdr
RE97_RS16725	COG1960	acyl-CoA dehydrogenase activity
RE97_RS16730	COG0318	PFAM AMP-dependent synthetase and ligase
RE97_RS16735	COG1960	acyl-CoA dehydrogenase activity
RE97_RS16740	COG1960	acyl-CoA dehydrogenase activity
RE97_RS16745	COG1960	acyl-CoA dehydrogenase activity
RE97_RS16750	COG0436	Aminotransferase
RE97_RS16800	COG1960	acyl-CoA dehydrogenase activity
RE97_RS16805	COG1309	transcriptional regulator
RE97_RS16810	COG1609	Transcriptional regulator
RE97_RS16820	COG1121	(ABC) transporter
RE97_RS16825	COG1108	ABC-type Mn2 Zn2 transport systems permease components
RE97_RS16830	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
RE97_RS16850	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RE97_RS16860	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
RE97_RS16865	COG0215	cysteine-tRNA ligase activity
RE97_RS16875	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
RE97_RS16895	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
RE97_RS16975	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
RE97_RS17005	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
RE97_RS17010	COG0302	gtp cyclohydrolase
RE97_RS17015	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
RE97_RS17030	COG2267	carboxylic ester hydrolase activity
RE97_RS17040	COG1063	alcohol dehydrogenase
RE97_RS17045	COG1403	HNH endonuclease
RE97_RS17060	COG3391	amine dehydrogenase activity
RE97_RS17075	COG0037	tRNA processing
RE97_RS17085	COG2027	D-alanyl-D-alanine carboxypeptidase
RE97_RS17105	COG1215	transferase activity, transferring glycosyl groups
RE97_RS17165	COG1205	dead DEAH box helicase
RE97_RS17165	COG1111	helicase
RE97_RS17225	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RE97_RS17230	COG0601	transmembrane transport
RE97_RS17245	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RE97_RS17280	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
RE97_RS17295	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RE97_RS17325	COG1408	metallophosphoesterase
RE97_RS17330	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
RE97_RS17390	COG1366	Belongs to the anti-sigma-factor antagonist family
RE97_RS17395	COG1366	Belongs to the anti-sigma-factor antagonist family
RE97_RS17400	COG2172	sigma factor antagonist activity
RE97_RS17420	COG2890	protein-(glutamine-N5) methyltransferase activity
RE97_RS17425	COG0693	protein deglycase activity
RE97_RS17430	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RE97_RS17440	COG0437	4 iron, 4 sulfur cluster binding
RE97_RS17445	COG0243	molybdopterin cofactor binding
RE97_RS17445	COG3383	formate dehydrogenase (NAD+) activity
RE97_RS17450	COG0243	molybdopterin cofactor binding
RE97_RS17450	COG3383	formate dehydrogenase (NAD+) activity
RE97_RS17455	COG0709	Synthesizes selenophosphate from selenide and ATP
RE97_RS17495	COG0714	Associated with various cellular activities
RE97_RS17520	COG1695	Transcriptional regulator
RE97_RS17525	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
RE97_RS17530	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
RE97_RS17550	COG3804	dihydrodipicolinate reductase
RE97_RS17570	COG0596	Alpha beta hydrolase
RE97_RS17575	COG2124	cytochrome p450
RE97_RS17590	COG1793	dna ligase
RE97_RS17630	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
RE97_RS17680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RE97_RS17690	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
RE97_RS17705	COG0860	N-Acetylmuramoyl-L-alanine amidase
RE97_RS17710	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
RE97_RS17725	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
RE97_RS17730	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
RE97_RS17780	COG0121	glutamine amidotransferase
RE97_RS17790	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
RE97_RS17810	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RE97_RS17815	COG3800	Transcriptional regulator
RE97_RS17815	COG1396	sequence-specific DNA binding
RE97_RS17825	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
RE97_RS17840	COG2301	Belongs to the HpcH HpaI aldolase family
RE97_RS17845	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RE97_RS17905	COG0590	tRNA wobble adenosine to inosine editing
RE97_RS17915	COG0287	Prephenate dehydrogenase
RE97_RS17930	COG1174	glycine betaine transport
RE97_RS17990	COG2015	COG2015, Alkyl sulfatase and related hydrolases
RE97_RS18000	COG2205	protein histidine kinase activity
RE97_RS18005	COG0745	RESPONSE REGULATOR receiver
RE97_RS18015	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
RE97_RS18045	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
RE97_RS18065	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
RE97_RS18085	COG0604	alcohol dehydrogenase
RE97_RS18135	COG0277	FAD linked oxidase domain protein
RE97_RS18140	COG1028	Short-chain dehydrogenase reductase Sdr
RE97_RS18195	COG1960	acyl-CoA dehydrogenase activity
RE97_RS18210	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
RE97_RS18215	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
RE97_RS18215	COG3321	synthase
RE97_RS18215	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
RE97_RS18220	COG0318	PFAM AMP-dependent synthetase and ligase
RE97_RS18225	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
RE97_RS18230	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
RE97_RS18240	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
RE97_RS18250	COG0671	phosphoesterase, PA-phosphatase related
RE97_RS18255	COG1216	Glycosyl transferase, family 2
RE97_RS18275	COG0561	phosphatase activity
RE97_RS18330	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
RE97_RS18365	COG1316	TRANSCRIPTIONal
RE97_RS18380	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
RE97_RS18415	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
RE97_RS18420	COG2072	flavoprotein involved in K transport
RE97_RS18425	COG1309	transcriptional regulator
RE97_RS18430	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
RE97_RS18435	COG1796	DNA polymerase
RE97_RS18435	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
RE97_RS18455	COG0067	glutamate synthase
RE97_RS18455	COG0069	glutamate synthase activity
RE97_RS18455	COG0070	glutamate synthase
RE97_RS18490	COG1404	Belongs to the peptidase S8 family
RE97_RS18540	COG1309	transcriptional regulator
RE97_RS18545	COG1024	Enoyl-CoA hydratase
RE97_RS18560	COG1960	acyl-CoA dehydrogenase activity
RE97_RS18565	COG4552	Acetyltransferase involved in intracellular survival and related
RE97_RS18580	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RE97_RS18585	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
RE97_RS18590	COG1116	anion transmembrane transporter activity
RE97_RS18605	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RE97_RS18630	COG0346	lactoylglutathione lyase activity
RE97_RS18635	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
RE97_RS18645	COG0477	Major facilitator Superfamily
RE97_RS18665	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
RE97_RS18670	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RE97_RS18675	COG0659	secondary active sulfate transmembrane transporter activity
RE97_RS18725	COG1309	transcriptional regulator
RE97_RS18775	COG4974	Belongs to the 'phage' integrase family
RE97_RS18790	COG3328	transposase activity
RE97_RS18830	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
RE97_RS18840	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
RE97_RS18860	COG1247	-acetyltransferase
RE97_RS18900	COG0277	FAD linked oxidase domain protein
RE97_RS18910	COG1028	Short-chain dehydrogenase reductase Sdr
RE97_RS18935	COG1309	transcriptional regulator
RE97_RS18955	COG0359	binds to the 23S rRNA
RE97_RS18970	COG0360	Binds together with S18 to 16S ribosomal RNA
RE97_RS18985	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
RE97_RS19030	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
RE97_RS19030	COG0596	Alpha beta hydrolase
RE97_RS19045	COG0765	amino acid transport
RE97_RS19065	COG0495	leucyl-tRNA aminoacylation
RE97_RS19125	COG0741	lytic transglycosylase activity
RE97_RS19125	COG0791	NLP P60 protein
RE97_RS19145	COG1960	acyl-CoA dehydrogenase activity
RE97_RS19165	COG3328	transposase activity
RE97_RS19200	COG1716	ATPase activity
RE97_RS19225	COG0515	serine threonine protein kinase
RE97_RS19290	COG1819	glycosyl
RE97_RS19300	COG0604	alcohol dehydrogenase
RE97_RS19300	COG3321	synthase
RE97_RS19300	COG1028	Short-chain dehydrogenase reductase Sdr
RE97_RS19310	COG0701	Predicted permease
RE97_RS19320	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
RE97_RS19325	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
RE97_RS19330	COG0267	Belongs to the bacterial ribosomal protein bL33 family
RE97_RS19340	COG0254	rRNA binding
RE97_RS19350	COG0523	cobalamin synthesis protein
RE97_RS19360	COG1108	ABC-type Mn2 Zn2 transport systems permease components
RE97_RS19365	COG1121	(ABC) transporter
RE97_RS19370	COG0803	Belongs to the bacterial solute-binding protein 9 family
RE97_RS19425	COG1404	Belongs to the peptidase S8 family
RE97_RS19450	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
RE97_RS19455	COG0778	Nitroreductase
RE97_RS19485	COG1309	transcriptional regulator
RE97_RS19520	COG2130	NADP-dependent
RE97_RS19555	COG0246	Mannitol dehydrogenase
RE97_RS19575	COG1376	ErfK ybiS ycfS ynhG family protein
RE97_RS19600	COG2124	cytochrome p450
RE97_RS19615	COG0717	Belongs to the dCTP deaminase family
RE97_RS19640	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
RE97_RS19670	COG0247	lactate metabolic process
RE97_RS19670	COG2181	nitrate reductase activity
RE97_RS19685	COG2814	Major facilitator Superfamily
RE97_RS19695	COG1511	domain protein
RE97_RS19715	COG0443	Heat shock 70 kDa protein
RE97_RS19720	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
RE97_RS19725	COG0484	heat shock protein binding
RE97_RS19730	COG0789	Transcriptional regulator
RE97_RS19790	COG0542	response to heat
RE97_RS19850	COG1994	Peptidase M50
RE97_RS19860	COG0406	alpha-ribazole phosphatase activity
RE97_RS19865	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
RE97_RS19880	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
RE97_RS19890	COG1252	NADH dehydrogenase
RE97_RS19905	COG1960	acyl-CoA dehydrogenase activity
RE97_RS19910	COG1960	acyl-CoA dehydrogenase activity
RE97_RS19915	COG1028	Short-chain dehydrogenase reductase Sdr
RE97_RS19925	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
RE97_RS19935	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RE97_RS19950	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
RE97_RS19975	COG1309	transcriptional regulator
RE97_RS19990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RE97_RS20005	COG0352	thiamine-phosphate diphosphorylase activity
RE97_RS20010	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
RE97_RS20010	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RE97_RS20020	COG2022	thiamine diphosphate biosynthetic process
RE97_RS20050	COG2234	aminopeptidase activity
RE97_RS20055	COG2234	aminopeptidase activity
RE97_RS20065	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RE97_RS20085	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
RE97_RS20115	COG0242	peptide deformylase activity
RE97_RS20130	COG2032	superoxide dismutase activity
RE97_RS20165	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
RE97_RS20180	COG0738	Major facilitator superfamily
RE97_RS20190	COG4221	oxidoreductase activity
RE97_RS20205	COG0459	protein refolding
RE97_RS20270	COG1024	Enoyl-CoA hydratase
RE97_RS20280	COG1505	serine-type exopeptidase activity
RE97_RS20340	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
RE97_RS20355	COG2733	membrane
RE97_RS20380	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
RE97_RS20400	COG0812	UDP-N-acetylmuramate dehydrogenase activity
RE97_RS20430	COG0588	phosphoglycerate mutase activity
RE97_RS20505	COG2030	dehydratase
RE97_RS20545	COG0181	hydroxymethylbilane synthase activity
RE97_RS20570	COG1366	Belongs to the anti-sigma-factor antagonist family
RE97_RS20580	COG2755	lipolytic protein G-D-S-L family
RE97_RS20585	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
RE97_RS20585	COG2755	lipolytic protein G-D-S-L family
RE97_RS20610	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
RE97_RS20615	COG4948	Mandelate Racemase Muconate Lactonizing
RE97_RS20630	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
RE97_RS20635	COG0406	alpha-ribazole phosphatase activity
RE97_RS20645	COG0785	Cytochrome C biogenesis protein
RE97_RS20655	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
RE97_RS20660	COG2894	cell division
RE97_RS20670	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
RE97_RS20680	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
RE97_RS20730	COG0306	phosphate transporter
RE97_RS20740	COG4221	oxidoreductase activity
RE97_RS20755	COG0667	Aldo Keto reductase
RE97_RS20765	COG0318	PFAM AMP-dependent synthetase and ligase
RE97_RS20770	COG1228	amidohydrolase
RE97_RS20775	COG4948	Mandelate Racemase Muconate Lactonizing
RE97_RS20800	COG2226	methyltransferase
RE97_RS20815	COG0142	geranyltranstransferase activity
RE97_RS20820	COG0501	Belongs to the peptidase M48B family
RE97_RS20830	COG0659	secondary active sulfate transmembrane transporter activity
RE97_RS20835	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
RE97_RS20840	COG2072	flavoprotein involved in K transport
RE97_RS20845	COG1666	GTP binding
RE97_RS20855	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
RE97_RS20860	COG1914	H( )-stimulated, divalent metal cation uptake system
RE97_RS20875	COG2124	cytochrome p450
RE97_RS20900	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
RE97_RS20920	COG3537	Alpha-1,2-mannosidase
RE97_RS20930	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
RE97_RS20960	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
RE97_RS20965	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
RE97_RS20990	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
RE97_RS21005	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
RE97_RS21015	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
RE97_RS21020	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
RE97_RS21040	COG1752	Esterase of the alpha-beta hydrolase superfamily
RE97_RS21050	COG0243	molybdopterin cofactor binding
RE97_RS21065	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RE97_RS21090	COG2030	dehydratase
RE97_RS21095	COG2030	dehydratase
RE97_RS21100	COG2030	dehydratase
RE97_RS21110	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
RE97_RS21130	COG4941	Belongs to the sigma-70 factor family
RE97_RS21140	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
RE97_RS21145	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
RE97_RS21150	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
RE97_RS21160	COG2318	DinB family
RE97_RS21190	COG0222	ribosome binding
RE97_RS21215	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
RE97_RS21225	COG1960	acyl-CoA dehydrogenase activity
RE97_RS21255	COG1309	transcriptional regulator
RE97_RS21290	COG1028	Short-chain dehydrogenase reductase Sdr
RE97_RS21300	COG0483	inositol monophosphate 1-phosphatase activity
RE97_RS21305	COG0656	L-ascorbic acid biosynthetic process
RE97_RS21325	COG0535	radical SAM domain protein
RE97_RS21370	COG0088	Forms part of the polypeptide exit tunnel
RE97_RS21380	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
RE97_RS21395	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
RE97_RS21410	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
RE97_RS21430	COG1262	PFAM Formylglycine-generating sulfatase enzyme
RE97_RS21455	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
RE97_RS21475	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
RE97_RS21480	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
RE97_RS21495	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RE97_RS21500	COG0616	signal peptide processing
RE97_RS21505	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
RE97_RS21510	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
RE97_RS21515	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
RE97_RS21520	COG1063	alcohol dehydrogenase
RE97_RS21530	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
RE97_RS21545	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
RE97_RS21555	COG0563	adenylate kinase activity
RE97_RS21575	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RE97_RS21590	COG0577	efflux transmembrane transporter activity
RE97_RS21595	COG0577	efflux transmembrane transporter activity
RE97_RS21595	COG1136	(ABC) transporter
RE97_RS21610	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
RE97_RS21615	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
RE97_RS21630	COG1960	acyl-CoA dehydrogenase activity
RE97_RS21655	COG3794	PFAM blue (type 1) copper domain protein
RE97_RS21705	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
RE97_RS21730	COG0203	ribosomal protein L17
RE97_RS21735	COG0101	tRNA pseudouridine synthase activity
RE97_RS21755	COG1404	Belongs to the peptidase S8 family
RE97_RS21765	COG1674	ftsk spoiiie
RE97_RS21775	COG4842	Belongs to the WXG100 family
RE97_RS21780	COG4842	Belongs to the WXG100 family
RE97_RS21790	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
RE97_RS21795	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
RE97_RS21810	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RE97_RS21825	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
RE97_RS21845	COG0076	glutamate decarboxylase activity
RE97_RS21870	COG0456	acetyltransferase
RE97_RS21885	COG0459	protein refolding
RE97_RS21895	COG1396	sequence-specific DNA binding
RE97_RS21900	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
RE97_RS21910	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RE97_RS21915	COG2032	superoxide dismutase activity
RE97_RS21965	COG1028	Short-chain dehydrogenase reductase Sdr
RE97_RS22010	COG1309	transcriptional regulator
RE97_RS22015	COG0596	Alpha beta hydrolase
RE97_RS22020	COG1028	Short-chain dehydrogenase reductase Sdr
RE97_RS22025	COG0318	PFAM AMP-dependent synthetase and ligase
RE97_RS22050	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RE97_RS22060	COG1609	Transcriptional regulator
RE97_RS22080	COG1960	acyl-CoA dehydrogenase activity
RE97_RS22085	COG1309	transcriptional regulator
RE97_RS22105	COG3588	fructose-bisphosphate aldolase
RE97_RS22135	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
RE97_RS22140	COG4638	Rieske (2fe-2S)
RE97_RS22150	COG2197	response regulator
RE97_RS22155	COG4585	Histidine kinase
RE97_RS22170	COG1674	ftsk spoiiie
RE97_RS22255	COG1595	DNA-templated transcription, initiation
RE97_RS22275	COG0860	N-Acetylmuramoyl-L-alanine amidase
RE97_RS22275	COG3409	Peptidoglycan-binding domain 1 protein
RE97_RS22290	COG1192	Involved in chromosome partitioning
RE97_RS22295	COG0357	Ribosomal RNA small subunit methyltransferase G
RE97_RS22305	COG0706	membrane insertase activity
RE97_RS22310	COG0594	ribonuclease P activity
RE97_RS22350	COG1403	HNH endonuclease