locus-tag	class	description
MAP_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MAP_RS00010	COG0592	DNA-directed DNA polymerase activity
MAP_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MAP_RS00020	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
MAP_RS00025	COG0187	DNA topoisomerase II activity
MAP_RS00120	COG1716	ATPase activity
MAP_RS00155	COG3328	transposase activity
MAP_RS00175	COG1960	acyl-CoA dehydrogenase activity
MAP_RS00195	COG0741	lytic transglycosylase activity
MAP_RS00195	COG0791	NLP P60 protein
MAP_RS00255	COG0495	leucyl-tRNA aminoacylation
MAP_RS00275	COG0765	amino acid transport
MAP_RS00290	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MAP_RS00290	COG0596	Alpha beta hydrolase
MAP_RS00335	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MAP_RS00350	COG0360	Binds together with S18 to 16S ribosomal RNA
MAP_RS00365	COG0359	binds to the 23S rRNA
MAP_RS00385	COG1309	transcriptional regulator
MAP_RS00410	COG1028	Short-chain dehydrogenase reductase Sdr
MAP_RS00420	COG0277	FAD linked oxidase domain protein
MAP_RS00460	COG1247	-acetyltransferase
MAP_RS00480	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MAP_RS00490	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MAP_RS00530	COG3328	transposase activity
MAP_RS00545	COG4974	Belongs to the 'phage' integrase family
MAP_RS00595	COG1309	transcriptional regulator
MAP_RS00645	COG0659	secondary active sulfate transmembrane transporter activity
MAP_RS00650	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MAP_RS00655	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MAP_RS00675	COG0477	Major facilitator Superfamily
MAP_RS00685	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MAP_RS00690	COG0346	lactoylglutathione lyase activity
MAP_RS00715	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MAP_RS00730	COG1116	anion transmembrane transporter activity
MAP_RS00735	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MAP_RS00740	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MAP_RS00755	COG4552	Acetyltransferase involved in intracellular survival and related
MAP_RS00760	COG1960	acyl-CoA dehydrogenase activity
MAP_RS00775	COG1024	Enoyl-CoA hydratase
MAP_RS00780	COG1309	transcriptional regulator
MAP_RS00830	COG1404	Belongs to the peptidase S8 family
MAP_RS00865	COG0069	glutamate synthase activity
MAP_RS00865	COG0070	glutamate synthase
MAP_RS00865	COG0067	glutamate synthase
MAP_RS00885	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
MAP_RS00885	COG1796	DNA polymerase
MAP_RS00890	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MAP_RS00895	COG1309	transcriptional regulator
MAP_RS00900	COG2072	flavoprotein involved in K transport
MAP_RS00905	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MAP_RS00940	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MAP_RS00955	COG1316	TRANSCRIPTIONal
MAP_RS00990	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MAP_RS01045	COG0561	phosphatase activity
MAP_RS01065	COG1216	Glycosyl transferase, family 2
MAP_RS01070	COG0671	phosphoesterase, PA-phosphatase related
MAP_RS01080	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MAP_RS01090	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
MAP_RS01095	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
MAP_RS01100	COG0318	PFAM AMP-dependent synthetase and ligase
MAP_RS01105	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MAP_RS01105	COG3321	synthase
MAP_RS01105	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
MAP_RS01110	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MAP_RS01125	COG1960	acyl-CoA dehydrogenase activity
MAP_RS01180	COG1028	Short-chain dehydrogenase reductase Sdr
MAP_RS01185	COG0277	FAD linked oxidase domain protein
MAP_RS01235	COG0604	alcohol dehydrogenase
MAP_RS01255	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MAP_RS01275	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MAP_RS01290	COG3415	Transposase
MAP_RS01290	COG2801	Transposase and inactivated derivatives
MAP_RS01305	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MAP_RS01315	COG0745	RESPONSE REGULATOR receiver
MAP_RS01320	COG2205	protein histidine kinase activity
MAP_RS01330	COG2015	COG2015, Alkyl sulfatase and related hydrolases
MAP_RS01390	COG1174	glycine betaine transport
MAP_RS01405	COG0287	Prephenate dehydrogenase
MAP_RS01415	COG0590	tRNA wobble adenosine to inosine editing
MAP_RS01475	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MAP_RS01480	COG2301	Belongs to the HpcH HpaI aldolase family
MAP_RS01495	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MAP_RS01505	COG3800	Transcriptional regulator
MAP_RS01505	COG1396	sequence-specific DNA binding
MAP_RS01510	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MAP_RS01525	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MAP_RS01535	COG0121	glutamine amidotransferase
MAP_RS01585	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MAP_RS01590	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MAP_RS01605	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MAP_RS01610	COG0860	N-Acetylmuramoyl-L-alanine amidase
MAP_RS01625	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MAP_RS01635	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MAP_RS01685	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
MAP_RS01730	COG1793	dna ligase
MAP_RS01745	COG2124	cytochrome p450
MAP_RS01750	COG0596	Alpha beta hydrolase
MAP_RS01770	COG3804	dihydrodipicolinate reductase
MAP_RS01790	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MAP_RS01795	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MAP_RS01800	COG1695	Transcriptional regulator
MAP_RS01825	COG0714	Associated with various cellular activities
MAP_RS01865	COG0709	Synthesizes selenophosphate from selenide and ATP
MAP_RS01870	COG0243	molybdopterin cofactor binding
MAP_RS01870	COG3383	formate dehydrogenase (NAD+) activity
MAP_RS01875	COG0243	molybdopterin cofactor binding
MAP_RS01875	COG3383	formate dehydrogenase (NAD+) activity
MAP_RS01880	COG0437	4 iron, 4 sulfur cluster binding
MAP_RS01890	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MAP_RS01895	COG0693	protein deglycase activity
MAP_RS01900	COG2890	protein-(glutamine-N5) methyltransferase activity
MAP_RS01920	COG2172	sigma factor antagonist activity
MAP_RS01925	COG1366	Belongs to the anti-sigma-factor antagonist family
MAP_RS01930	COG1366	Belongs to the anti-sigma-factor antagonist family
MAP_RS01990	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MAP_RS01995	COG1408	metallophosphoesterase
MAP_RS02025	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MAP_RS02040	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MAP_RS02075	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MAP_RS02090	COG0601	transmembrane transport
MAP_RS02095	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MAP_RS02155	COG1205	dead DEAH box helicase
MAP_RS02155	COG1111	helicase
MAP_RS02180	COG0470	DNA polymerase III
MAP_RS02190	COG2801	Transposase and inactivated derivatives
MAP_RS02190	COG3415	Transposase
MAP_RS02210	COG1215	transferase activity, transferring glycosyl groups
MAP_RS02230	COG2027	D-alanyl-D-alanine carboxypeptidase
MAP_RS02240	COG0037	tRNA processing
MAP_RS02255	COG3391	amine dehydrogenase activity
MAP_RS02270	COG1403	HNH endonuclease
MAP_RS02275	COG1063	alcohol dehydrogenase
MAP_RS02285	COG2267	carboxylic ester hydrolase activity
MAP_RS02300	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MAP_RS02305	COG0302	gtp cyclohydrolase
MAP_RS02310	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MAP_RS02340	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MAP_RS02420	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
MAP_RS02440	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
MAP_RS02450	COG0215	cysteine-tRNA ligase activity
MAP_RS02455	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MAP_RS02465	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MAP_RS02485	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
MAP_RS02490	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MAP_RS02495	COG1121	(ABC) transporter
MAP_RS02505	COG1609	Transcriptional regulator
MAP_RS02510	COG1309	transcriptional regulator
MAP_RS02515	COG1960	acyl-CoA dehydrogenase activity
MAP_RS02565	COG0436	Aminotransferase
MAP_RS02570	COG1960	acyl-CoA dehydrogenase activity
MAP_RS02575	COG1960	acyl-CoA dehydrogenase activity
MAP_RS02580	COG1960	acyl-CoA dehydrogenase activity
MAP_RS02585	COG0318	PFAM AMP-dependent synthetase and ligase
MAP_RS02590	COG1960	acyl-CoA dehydrogenase activity
MAP_RS02595	COG1028	Short-chain dehydrogenase reductase Sdr
MAP_RS02605	COG0183	Belongs to the thiolase family
MAP_RS02635	COG1024	Enoyl-CoA hydratase
MAP_RS02640	COG1028	Short-chain dehydrogenase reductase Sdr
MAP_RS02645	COG1028	Short-chain dehydrogenase reductase Sdr
MAP_RS02660	COG0183	Belongs to the thiolase family
MAP_RS02665	COG2124	cytochrome p450
MAP_RS02670	COG1960	acyl-CoA dehydrogenase activity
MAP_RS02675	COG1960	acyl-CoA dehydrogenase activity
MAP_RS02680	COG2030	dehydratase
MAP_RS02700	COG2030	dehydratase
MAP_RS02705	COG1053	succinate dehydrogenase
MAP_RS02710	COG3971	2-oxopent-4-enoate hydratase activity
MAP_RS02715	COG4569	acetaldehyde dehydrogenase (acetylating) activity
MAP_RS02720	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MAP_RS02750	COG4638	Rieske (2fe-2S)
MAP_RS02765	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MAP_RS02780	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MAP_RS02790	COG2124	cytochrome p450
MAP_RS02800	COG1024	Enoyl-CoA hydratase
MAP_RS02810	COG3001	Fructosamine kinase
MAP_RS02820	COG0028	Belongs to the TPP enzyme family
MAP_RS02835	COG0318	PFAM AMP-dependent synthetase and ligase
MAP_RS02845	COG1960	acyl-CoA dehydrogenase activity
MAP_RS02855	COG1028	Short-chain dehydrogenase reductase Sdr
MAP_RS02865	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MAP_RS02890	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MAP_RS02915	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
MAP_RS02920	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MAP_RS02925	COG0390	transport system, permease component
MAP_RS02930	COG1024	Enoyl-CoA hydratase
MAP_RS02945	COG1316	TRANSCRIPTIONal
MAP_RS02955	COG0154	amidase activity
MAP_RS02995	COG2801	Transposase and inactivated derivatives
MAP_RS02995	COG3415	Transposase
MAP_RS03010	COG0745	RESPONSE REGULATOR receiver
MAP_RS03015	COG2205	protein histidine kinase activity
MAP_RS03045	COG2124	cytochrome p450
MAP_RS03050	COG4221	oxidoreductase activity
MAP_RS03110	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MAP_RS03125	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
MAP_RS03145	COG0477	Major facilitator Superfamily
MAP_RS03150	COG0477	Major facilitator Superfamily
MAP_RS03165	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
MAP_RS03175	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MAP_RS03180	COG0047	phosphoribosylformylglycinamidine synthase activity
MAP_RS03205	COG2837	iron assimilation
MAP_RS03225	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MAP_RS03245	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
MAP_RS03255	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MAP_RS03265	COG4044	May play a role in the intracellular transport of hydrophobic ligands
MAP_RS03290	COG3118	belongs to the thioredoxin family
MAP_RS03300	COG0745	RESPONSE REGULATOR receiver
MAP_RS03305	COG0456	acetyltransferase
MAP_RS03305	COG0454	-acetyltransferase
MAP_RS03325	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MAP_RS03365	COG0640	Transcriptional regulator
MAP_RS03370	COG0590	tRNA wobble adenosine to inosine editing
MAP_RS03375	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MAP_RS03380	COG3415	Transposase
MAP_RS03380	COG2801	Transposase and inactivated derivatives
MAP_RS03405	COG1028	Short-chain dehydrogenase reductase Sdr
MAP_RS03420	COG2124	cytochrome p450
MAP_RS03440	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
MAP_RS03440	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
MAP_RS03445	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
MAP_RS03450	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MAP_RS03455	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MAP_RS03470	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MAP_RS03480	COG1960	acyl-CoA dehydrogenase activity
MAP_RS03485	COG1960	acyl-CoA dehydrogenase activity
MAP_RS03495	COG0596	Alpha beta hydrolase
MAP_RS03500	COG3479	Phenolic acid decarboxylase
MAP_RS03505	COG0183	Belongs to the thiolase family
MAP_RS03515	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MAP_RS03525	COG4585	Histidine kinase
MAP_RS03530	COG1053	succinate dehydrogenase
MAP_RS03540	COG2267	carboxylic ester hydrolase activity
MAP_RS03545	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MAP_RS03550	COG3384	dioxygenase
MAP_RS03555	COG1053	succinate dehydrogenase
MAP_RS03565	COG1028	Short-chain dehydrogenase reductase Sdr
MAP_RS03580	COG2132	Multicopper oxidase
MAP_RS03620	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MAP_RS03625	COG1028	Short-chain dehydrogenase reductase Sdr
MAP_RS03635	COG1028	Short-chain dehydrogenase reductase Sdr
MAP_RS03645	COG1960	acyl-CoA dehydrogenase activity
MAP_RS03660	COG1960	acyl-CoA dehydrogenase activity
MAP_RS03670	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MAP_RS03680	COG4638	Rieske (2fe-2S)
MAP_RS03700	COG0183	Belongs to the thiolase family
MAP_RS03705	COG1309	transcriptional regulator
MAP_RS03715	COG2124	cytochrome p450
MAP_RS03735	COG2124	cytochrome p450
MAP_RS03775	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
MAP_RS03815	COG0778	Nitroreductase
MAP_RS03815	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
MAP_RS03820	COG1960	acyl-CoA dehydrogenase activity
MAP_RS03825	COG1960	acyl-CoA dehydrogenase activity
MAP_RS03870	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MAP_RS03875	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MAP_RS03880	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MAP_RS03905	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MAP_RS03935	COG1309	transcriptional regulator
MAP_RS03965	COG1309	transcriptional regulator
MAP_RS03975	COG1024	Enoyl-CoA hydratase
MAP_RS03990	COG0318	PFAM AMP-dependent synthetase and ligase
MAP_RS04005	COG3961	Belongs to the TPP enzyme family
MAP_RS04015	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MAP_RS04035	COG0183	Belongs to the thiolase family
MAP_RS04040	COG1024	Enoyl-CoA hydratase
MAP_RS04040	COG1250	3-hydroxyacyl-CoA dehydrogenase
MAP_RS04065	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MAP_RS04080	COG0183	Belongs to the thiolase family
MAP_RS04085	COG1061	Type III restriction enzyme res subunit
MAP_RS04105	COG0521	Mo-molybdopterin cofactor biosynthetic process
MAP_RS04130	COG3304	Inner membrane component domain
MAP_RS04135	COG1278	Cold shock
MAP_RS04145	COG0435	Glutathione S-transferase
MAP_RS04160	COG2814	Major facilitator Superfamily
MAP_RS04200	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MAP_RS04225	COG0259	pyridoxamine-phosphate oxidase activity
MAP_RS04245	COG3547	Transposase (IS116 IS110 IS902 family)
MAP_RS04255	COG0745	RESPONSE REGULATOR receiver
MAP_RS04265	COG0438	transferase activity, transferring glycosyl groups
MAP_RS04275	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MAP_RS04335	COG3328	transposase activity
MAP_RS04340	COG2801	Transposase and inactivated derivatives
MAP_RS04340	COG3415	Transposase
MAP_RS04395	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MAP_RS04445	COG0246	Mannitol dehydrogenase
MAP_RS04450	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MAP_RS04470	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MAP_RS04505	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
MAP_RS04515	COG0166	Belongs to the GPI family
MAP_RS04535	COG4942	peptidase
MAP_RS04575	COG0138	bifunctional purine biosynthesis protein purh
MAP_RS04605	COG1024	Enoyl-CoA hydratase
MAP_RS04620	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MAP_RS04625	COG1960	acyl-CoA dehydrogenase activity
MAP_RS04645	COG2205	protein histidine kinase activity
MAP_RS04650	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MAP_RS04655	COG0521	Mo-molybdopterin cofactor biosynthetic process
MAP_RS04655	COG0315	cyclic pyranopterin monophosphate synthase activity
MAP_RS04660	COG1970	mechanosensitive ion channel activity
MAP_RS04675	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MAP_RS04680	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MAP_RS04725	COG4638	Rieske (2fe-2S)
MAP_RS04740	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
MAP_RS04745	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
MAP_RS04750	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MAP_RS04750	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MAP_RS04785	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MAP_RS04830	COG0297	glycogen (starch) synthase activity
MAP_RS04830	COG0438	transferase activity, transferring glycosyl groups
MAP_RS04870	COG0297	glycogen (starch) synthase activity
MAP_RS04885	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
MAP_RS04930	COG0084	hydrolase, TatD family'
MAP_RS04940	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
MAP_RS04945	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MAP_RS04950	COG0318	PFAM AMP-dependent synthetase and ligase
MAP_RS04955	COG0193	aminoacyl-tRNA hydrolase activity
MAP_RS04960	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MAP_RS04975	COG1393	Belongs to the ArsC family
MAP_RS04985	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MAP_RS05010	COG3956	TIGRFAM MazG family protein
MAP_RS05055	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
MAP_RS05065	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
MAP_RS05080	COG2205	protein histidine kinase activity
MAP_RS05085	COG0745	RESPONSE REGULATOR receiver
MAP_RS05135	COG3391	amine dehydrogenase activity
MAP_RS05140	COG0318	PFAM AMP-dependent synthetase and ligase
MAP_RS05150	COG0121	glutamine amidotransferase
MAP_RS05190	COG1024	Enoyl-CoA hydratase
MAP_RS05205	COG2755	lipolytic protein G-D-S-L family
MAP_RS05210	COG0657	acetylesterase activity
MAP_RS05245	COG0217	transcriptional regulatory protein
MAP_RS05255	COG3766	membrane
MAP_RS05300	COG1022	Amp-dependent synthetase and ligase
MAP_RS05300	COG3320	Male sterility
MAP_RS05315	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MAP_RS05320	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MAP_RS05325	COG0747	negative chemotaxis
MAP_RS05330	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MAP_RS05335	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MAP_RS05340	COG2801	Transposase and inactivated derivatives
MAP_RS05340	COG3415	Transposase
MAP_RS05355	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MAP_RS05360	COG0124	histidyl-tRNA synthetase
MAP_RS05365	COG1403	HNH endonuclease
MAP_RS05390	COG1396	sequence-specific DNA binding
MAP_RS05395	COG0235	Class ii aldolase
MAP_RS05400	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MAP_RS05420	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MAP_RS05490	COG0432	Pfam Uncharacterised protein family UPF0047
MAP_RS05500	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MAP_RS05505	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MAP_RS05510	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MAP_RS05520	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MAP_RS05525	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MAP_RS05550	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MAP_RS05560	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MAP_RS05570	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MAP_RS05575	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
MAP_RS05585	COG0006	proline dipeptidase activity
MAP_RS05615	COG2205	protein histidine kinase activity
MAP_RS05620	COG0745	RESPONSE REGULATOR receiver
MAP_RS05635	COG2188	Transcriptional regulator
MAP_RS05660	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
MAP_RS05665	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MAP_RS05675	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MAP_RS05695	COG0505	Belongs to the CarA family
MAP_RS05705	COG0284	orotidine-5'-phosphate decarboxylase activity
MAP_RS05720	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
MAP_RS05725	COG1758	RNA polymerase activity
MAP_RS05735	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MAP_RS05740	COG2072	flavoprotein involved in K transport
MAP_RS05745	COG0657	acetylesterase activity
MAP_RS05770	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MAP_RS05805	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MAP_RS05805	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MAP_RS05810	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
MAP_RS05835	COG0322	excinuclease ABC activity
MAP_RS05840	COG1660	Displays ATPase and GTPase activities
MAP_RS05855	COG3328	transposase activity
MAP_RS05890	COG0657	acetylesterase activity
MAP_RS05895	COG0318	PFAM AMP-dependent synthetase and ligase
MAP_RS05930	COG0149	triose-phosphate isomerase activity
MAP_RS05945	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MAP_RS05955	COG0667	Aldo Keto reductase
MAP_RS05960	COG0123	including yeast histone deacetylase and acetoin utilization protein
MAP_RS05985	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MAP_RS05995	COG0109	protoheme IX farnesyltransferase activity
MAP_RS06045	COG0396	ATPase activity
MAP_RS06060	COG2151	metal-sulfur cluster biosynthetic enzyme
MAP_RS06080	COG1960	acyl-CoA dehydrogenase activity
MAP_RS06085	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MAP_RS06095	COG0488	(ABC) transporter
MAP_RS06105	COG1309	transcriptional regulator
MAP_RS06120	COG0791	NLP P60 protein
MAP_RS06120	COG3883	PFAM NLP P60 protein
MAP_RS06130	COG0714	Associated with various cellular activities
MAP_RS06140	COG2304	oxidoreductase activity
MAP_RS06160	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
MAP_RS06205	COG0745	RESPONSE REGULATOR receiver
MAP_RS06210	COG5002	protein histidine kinase activity
MAP_RS06240	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MAP_RS06255	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
MAP_RS06260	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MAP_RS06315	COG2070	2-Nitropropane dioxygenase
MAP_RS06325	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MAP_RS06340	COG0252	asparaginase activity
MAP_RS06360	COG2346	COG2346, Truncated hemoglobins
MAP_RS06370	COG0300	oxidoreductase activity
MAP_RS06455	COG0791	NLP P60 protein
MAP_RS06455	COG3883	PFAM NLP P60 protein
MAP_RS06465	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MAP_RS06470	COG0156	8-amino-7-oxononanoate synthase activity
MAP_RS06490	COG5002	protein histidine kinase activity
MAP_RS06515	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MAP_RS06535	COG3547	Transposase (IS116 IS110 IS902 family)
MAP_RS06545	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MAP_RS06550	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
MAP_RS06555	COG0157	Belongs to the NadC ModD family
MAP_RS06565	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MAP_RS06570	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MAP_RS06580	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MAP_RS06585	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MAP_RS06590	COG0483	inositol monophosphate 1-phosphatase activity
MAP_RS06595	COG0107	imidazoleglycerol-phosphate synthase activity
MAP_RS06600	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MAP_RS06605	COG0387	Pfam Sodium calcium exchanger
MAP_RS06635	COG0159	tryptophan synthase activity
MAP_RS06655	COG1946	Acyl-CoA thioesterase
MAP_RS06665	COG1132	(ABC) transporter
MAP_RS06670	COG4988	ABC transporter
MAP_RS06675	COG1294	oxidase, subunit
MAP_RS06680	COG1271	oxidase subunit
MAP_RS06705	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MAP_RS06725	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
MAP_RS06735	COG0237	dephospho-CoA kinase activity
MAP_RS06735	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MAP_RS06745	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
MAP_RS06760	COG0842	Transport permease protein
MAP_RS06760	COG1131	(ABC) transporter
MAP_RS06760	COG1716	ATPase activity
MAP_RS06795	COG1285	pathogenesis
MAP_RS06850	COG1309	transcriptional regulator
MAP_RS06905	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MAP_RS06910	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MAP_RS06910	COG0072	phenylalanine-tRNA ligase activity
MAP_RS06915	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MAP_RS06920	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MAP_RS06925	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
MAP_RS06935	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MAP_RS06940	COG1438	arginine binding
MAP_RS06945	COG0137	argininosuccinate synthase activity
MAP_RS06950	COG0165	Argininosuccinate lyase
MAP_RS06960	COG3321	synthase
MAP_RS06960	COG0604	alcohol dehydrogenase
MAP_RS06965	COG0604	alcohol dehydrogenase
MAP_RS06965	COG0604	alcohol dehydrogenase
MAP_RS06965	COG3321	synthase
MAP_RS06965	COG3321	synthase
MAP_RS06980	COG0488	(ABC) transporter
MAP_RS06985	COG3707	response regulator
MAP_RS06990	COG0583	DNA-binding transcription factor activity
MAP_RS07010	COG1028	Short-chain dehydrogenase reductase Sdr
MAP_RS07015	COG1028	Short-chain dehydrogenase reductase Sdr
MAP_RS07020	COG4948	Mandelate Racemase Muconate Lactonizing
MAP_RS07025	COG4221	oxidoreductase activity
MAP_RS07060	COG2835	tetraacyldisaccharide 4'-kinase activity
MAP_RS07065	COG1309	transcriptional regulator
MAP_RS07075	COG1131	(ABC) transporter
MAP_RS07085	COG2094	Belongs to the DNA glycosylase MPG family
MAP_RS07090	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MAP_RS07105	COG0647	UMP catabolic process
MAP_RS07120	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MAP_RS07145	COG0494	nUDIX hydrolase
MAP_RS07170	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MAP_RS07180	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
MAP_RS07185	COG1160	GTP binding
MAP_RS07225	COG0189	ligase activity
MAP_RS07225	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MAP_RS07230	COG2271	Major facilitator Superfamily
MAP_RS07250	COG2132	Multicopper oxidase
MAP_RS07275	COG1403	HNH endonuclease
MAP_RS07280	COG1053	succinate dehydrogenase
MAP_RS07295	COG1028	Short-chain dehydrogenase reductase Sdr
MAP_RS07300	COG1028	Short-chain dehydrogenase reductase Sdr
MAP_RS07310	COG0657	acetylesterase activity
MAP_RS07325	COG2072	flavoprotein involved in K transport
MAP_RS07330	COG1028	Short-chain dehydrogenase reductase Sdr
MAP_RS07345	COG0657	acetylesterase activity
MAP_RS07360	COG0346	lactoylglutathione lyase activity
MAP_RS07375	COG2072	flavoprotein involved in K transport
MAP_RS07385	COG2267	carboxylic ester hydrolase activity
MAP_RS07400	COG1028	Short-chain dehydrogenase reductase Sdr
MAP_RS07405	COG0657	acetylesterase activity
MAP_RS07410	COG0842	Transport permease protein
MAP_RS07410	COG1131	(ABC) transporter
MAP_RS07410	COG1716	ATPase activity
MAP_RS07415	COG1960	acyl-CoA dehydrogenase activity
MAP_RS07420	COG1960	acyl-CoA dehydrogenase activity
MAP_RS07445	COG2072	flavoprotein involved in K transport
MAP_RS07450	COG0318	PFAM AMP-dependent synthetase and ligase
MAP_RS07470	COG4221	oxidoreductase activity
MAP_RS07530	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MAP_RS07535	COG0513	Belongs to the DEAD box helicase family
MAP_RS07545	COG1053	succinate dehydrogenase
MAP_RS07565	COG1024	Enoyl-CoA hydratase
MAP_RS07575	COG0022	dehydrogenase e1 component
MAP_RS07580	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MAP_RS07585	COG1028	Short-chain dehydrogenase reductase Sdr
MAP_RS07620	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MAP_RS07660	COG5651	PPE family
MAP_RS07670	COG5651	PPE family
MAP_RS07700	COG1404	Belongs to the peptidase S8 family
MAP_RS07715	COG0657	acetylesterase activity
MAP_RS07760	COG5651	PPE family
MAP_RS07770	COG1285	pathogenesis
MAP_RS07800	COG1053	succinate dehydrogenase
MAP_RS07815	COG0653	protein targeting
MAP_RS07865	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MAP_RS07865	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MAP_RS07885	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
MAP_RS07890	COG1253	flavin adenine dinucleotide binding
MAP_RS07895	COG1253	flavin adenine dinucleotide binding
MAP_RS07900	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MAP_RS07905	COG1960	acyl-CoA dehydrogenase activity
MAP_RS07910	COG0318	PFAM AMP-dependent synthetase and ligase
MAP_RS07915	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MAP_RS07925	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MAP_RS07945	COG1252	NADH dehydrogenase
MAP_RS07955	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MAP_RS08005	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
MAP_RS08010	COG4221	oxidoreductase activity
MAP_RS08015	COG1968	undecaprenyl-diphosphatase activity
MAP_RS08020	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MAP_RS08025	COG0183	Belongs to the thiolase family
MAP_RS08080	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MAP_RS08105	COG1024	Enoyl-CoA hydratase
MAP_RS08115	COG2193	ferroxidase activity
MAP_RS08125	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MAP_RS08135	COG0174	glutamine synthetase
MAP_RS08175	COG1652	LysM domain
MAP_RS08225	COG2070	2-Nitropropane dioxygenase
MAP_RS08230	COG1403	HNH endonuclease
MAP_RS08240	COG1063	alcohol dehydrogenase
MAP_RS08245	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MAP_RS08250	COG1490	D-aminoacyl-tRNA deacylase activity
MAP_RS08260	COG1546	Belongs to the CinA family
MAP_RS08260	COG1058	Belongs to the CinA family
MAP_RS08265	COG2814	Major facilitator Superfamily
MAP_RS08275	COG1950	PFAM Membrane protein of
MAP_RS08320	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
MAP_RS08340	COG0640	Transcriptional regulator
MAP_RS08395	COG4977	sequence-specific DNA binding
MAP_RS08425	COG1012	belongs to the aldehyde dehydrogenase family
MAP_RS08440	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MAP_RS08465	COG2226	methyltransferase
MAP_RS08470	COG0438	transferase activity, transferring glycosyl groups
MAP_RS08475	COG3757	hydrolase, family 25
MAP_RS08480	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
MAP_RS08490	COG1376	ErfK ybiS ycfS ynhG family protein
MAP_RS08500	COG0723	plastoquinol--plastocyanin reductase activity
MAP_RS08545	COG1024	Enoyl-CoA hydratase
MAP_RS08560	COG1643	Atp-dependent helicase
MAP_RS08565	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MAP_RS08575	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MAP_RS08605	COG1028	Short-chain dehydrogenase reductase Sdr
MAP_RS08610	COG0545	Peptidyl-prolyl cis-trans isomerase
MAP_RS08620	COG0484	heat shock protein binding
MAP_RS08630	COG0789	Transcriptional regulator
MAP_RS08640	COG0301	tRNA thio-modification
MAP_RS08685	COG1028	Short-chain dehydrogenase reductase Sdr
MAP_RS08700	COG2267	carboxylic ester hydrolase activity
MAP_RS08705	COG1309	transcriptional regulator
MAP_RS08715	COG1960	acyl-CoA dehydrogenase activity
MAP_RS08720	COG0183	Belongs to the thiolase family
MAP_RS08730	COG1028	Short-chain dehydrogenase reductase Sdr
MAP_RS08780	COG0753	catalase activity
MAP_RS08805	COG1946	Acyl-CoA thioesterase
MAP_RS08830	COG0657	acetylesterase activity
MAP_RS08895	COG1960	acyl-CoA dehydrogenase activity
MAP_RS08910	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MAP_RS08915	COG0667	Aldo Keto reductase
MAP_RS08955	COG2837	iron assimilation
MAP_RS08980	COG1752	Esterase of the alpha-beta hydrolase superfamily
MAP_RS08985	COG3842	ATPase activity
MAP_RS08990	COG0395	ABC-type sugar transport system, permease component
MAP_RS08995	COG1175	transmembrane transport
MAP_RS09005	COG1595	DNA-templated transcription, initiation
MAP_RS09025	COG1335	isochorismatase
MAP_RS09045	COG3265	gluconokinase activity
MAP_RS09055	COG2272	Belongs to the type-B carboxylesterase lipase family
MAP_RS09110	COG0714	Associated with various cellular activities
MAP_RS09140	COG3321	synthase
MAP_RS09140	COG0604	alcohol dehydrogenase
MAP_RS09165	COG1574	metal-dependent hydrolase with the TIM-barrel fold
MAP_RS09175	COG0412	Dienelactone hydrolase
MAP_RS09205	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MAP_RS09270	COG2826	transposase and inactivated derivatives, IS30 family
MAP_RS09305	COG2378	regulation of single-species biofilm formation
MAP_RS09325	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
MAP_RS09385	COG0140	phosphoribosyl-ATP diphosphatase activity
MAP_RS09400	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MAP_RS09445	COG1410	methionine synthase
MAP_RS09445	COG0646	methionine synthase
MAP_RS09455	COG1028	Short-chain dehydrogenase reductase Sdr
MAP_RS09480	COG3321	synthase
MAP_RS09480	COG1028	Short-chain dehydrogenase reductase Sdr
MAP_RS09480	COG0604	alcohol dehydrogenase
MAP_RS09505	COG0028	Belongs to the TPP enzyme family
MAP_RS09520	COG0215	cysteine-tRNA ligase activity
MAP_RS09525	COG1218	3'(2'),5'-bisphosphate nucleotidase
MAP_RS09560	COG0167	dihydroorotate dehydrogenase activity
MAP_RS09565	COG1403	HNH endonuclease
MAP_RS09575	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MAP_RS09610	COG1799	cell septum assembly
MAP_RS09625	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MAP_RS09635	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MAP_RS09640	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MAP_RS09650	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MAP_RS09655	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MAP_RS09665	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MAP_RS09670	COG0768	penicillin binding
MAP_RS09680	COG0275	rRNA processing
MAP_RS09710	COG0142	geranyltranstransferase activity
MAP_RS09730	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MAP_RS09735	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
MAP_RS09765	COG0003	Pfam Anion-transporting ATPase
MAP_RS09780	COG1022	Amp-dependent synthetase and ligase
MAP_RS09815	COG1845	cytochrome c oxidase, subunit III
MAP_RS09855	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MAP_RS09865	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MAP_RS09895	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
MAP_RS09900	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
MAP_RS09905	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MAP_RS09910	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MAP_RS09920	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MAP_RS09950	COG0321	lipoyl(octanoyl) transferase activity
MAP_RS09955	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MAP_RS09985	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
MAP_RS10010	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
MAP_RS10095	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
MAP_RS10105	COG0596	Alpha beta hydrolase
MAP_RS10150	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MAP_RS10170	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MAP_RS10200	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MAP_RS10260	COG2072	flavoprotein involved in K transport
MAP_RS10275	COG0860	N-Acetylmuramoyl-L-alanine amidase
MAP_RS10300	COG1487	ribonuclease activity
MAP_RS10340	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MAP_RS10360	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
MAP_RS10370	COG0657	acetylesterase activity
MAP_RS10385	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MAP_RS10390	COG0438	transferase activity, transferring glycosyl groups
MAP_RS10415	COG3547	Transposase (IS116 IS110 IS902 family)
MAP_RS10420	COG2124	cytochrome p450
MAP_RS10435	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MAP_RS10440	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
MAP_RS10450	COG0596	Alpha beta hydrolase
MAP_RS10475	COG0697	spore germination
MAP_RS10490	COG2239	Acts as a magnesium transporter
MAP_RS10510	COG0326	Molecular chaperone. Has ATPase activity
MAP_RS10535	COG2226	methyltransferase
MAP_RS10540	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MAP_RS10555	COG3629	intracellular signal transduction
MAP_RS10555	COG3903	Transcriptional regulator
MAP_RS10570	COG0563	adenylate kinase activity
MAP_RS10580	COG1012	belongs to the aldehyde dehydrogenase family
MAP_RS10625	COG1175	transmembrane transport
MAP_RS10630	COG0395	ABC-type sugar transport system, permease component
MAP_RS10640	COG0531	amino acid
MAP_RS10645	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MAP_RS10650	COG1834	amidinotransferase
MAP_RS10655	COG1522	sequence-specific DNA binding
MAP_RS10675	COG1131	(ABC) transporter
MAP_RS10675	COG0842	Transport permease protein
MAP_RS10675	COG1716	ATPase activity
MAP_RS10685	COG2223	nitrite transmembrane transporter activity
MAP_RS10695	COG0243	molybdopterin cofactor binding
MAP_RS10700	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MAP_RS10735	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MAP_RS10760	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MAP_RS10765	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MAP_RS10770	COG4424	Sulfotransferase
MAP_RS10775	COG2855	membrane
MAP_RS10780	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MAP_RS10800	COG1045	serine acetyltransferase
MAP_RS10810	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MAP_RS10815	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MAP_RS10865	COG0423	glycine-tRNA ligase activity
MAP_RS10890	COG1381	Involved in DNA repair and RecF pathway recombination
MAP_RS10900	COG1982	Orn Lys Arg decarboxylase major
MAP_RS10905	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MAP_RS10935	COG3328	transposase activity
MAP_RS10950	COG2963	transposase activity
MAP_RS10955	COG2801	Transposase and inactivated derivatives
MAP_RS10985	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MAP_RS11000	COG0484	heat shock protein binding
MAP_RS11005	COG1420	regulation of RNA biosynthetic process
MAP_RS11020	COG1595	DNA-templated transcription, initiation
MAP_RS11040	COG3486	L-lysine 6-monooxygenase (NADPH) activity
MAP_RS11055	COG0604	alcohol dehydrogenase
MAP_RS11055	COG3321	synthase
MAP_RS11070	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MAP_RS11075	COG1021	2,3-dihydroxybenzoate-AMP ligase
MAP_RS11090	COG1309	transcriptional regulator
MAP_RS11115	COG1012	belongs to the aldehyde dehydrogenase family
MAP_RS11120	COG1012	belongs to the aldehyde dehydrogenase family
MAP_RS11125	COG0318	PFAM AMP-dependent synthetase and ligase
MAP_RS11175	COG0657	acetylesterase activity
MAP_RS11180	COG0300	oxidoreductase activity
MAP_RS11190	COG2072	flavoprotein involved in K transport
MAP_RS11215	COG1169	isochorismate synthase
MAP_RS11230	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MAP_RS11240	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
MAP_RS11245	COG4208	sulfate ABC transporter
MAP_RS11250	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
MAP_RS11255	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
MAP_RS11265	COG3387	PFAM Glycoside hydrolase 15-related
MAP_RS11275	COG0481	GTPase activity
MAP_RS11290	COG1234	tRNA 3'-trailer cleavage
MAP_RS11310	COG2308	Evidence 4 Homologs of previously reported genes of
MAP_RS11325	COG0658	competence protein
MAP_RS11325	COG2333	competence protein COMEC
MAP_RS11330	COG1555	photosystem II stabilization
MAP_RS11330	COG1596	polysaccharide export
MAP_RS11335	COG1960	acyl-CoA dehydrogenase activity
MAP_RS11340	COG1960	acyl-CoA dehydrogenase activity
MAP_RS11370	COG5651	PPE family
MAP_RS11375	COG0318	PFAM AMP-dependent synthetase and ligase
MAP_RS11405	COG2755	lipolytic protein G-D-S-L family
MAP_RS11415	COG0799	negative regulation of ribosome biogenesis
MAP_RS11420	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MAP_RS11430	COG0542	response to heat
MAP_RS11435	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MAP_RS11450	COG5002	protein histidine kinase activity
MAP_RS11455	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MAP_RS11460	COG2188	Transcriptional regulator
MAP_RS11475	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MAP_RS11480	COG0066	3-isopropylmalate dehydratase activity
MAP_RS11515	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MAP_RS11520	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MAP_RS11535	COG1530	ribonuclease E activity
MAP_RS11540	COG0105	UTP biosynthetic process
MAP_RS11550	COG0285	dihydrofolate synthase activity
MAP_RS11555	COG0525	valine-tRNA ligase activity
MAP_RS11560	COG3268	Saccharopine dehydrogenase
MAP_RS11565	COG1388	LysM domain
MAP_RS11570	COG3328	transposase activity
MAP_RS11575	COG0746	molybdenum cofactor guanylyltransferase activity
MAP_RS11580	COG1013	pyruvate-flavodoxin oxidoreductase activity
MAP_RS11585	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
MAP_RS11585	COG0674	pyruvate-flavodoxin oxidoreductase activity
MAP_RS11595	COG2040	homocysteine
MAP_RS11600	COG0740	serine-type endopeptidase activity
MAP_RS11605	COG0740	serine-type endopeptidase activity
MAP_RS11625	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MAP_RS11635	COG0698	ribose 5-phosphate isomerase
MAP_RS11640	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
MAP_RS11665	COG2346	COG2346, Truncated hemoglobins
MAP_RS11670	COG0366	Alpha amylase catalytic
MAP_RS11690	COG2902	Dehydrogenase
MAP_RS11700	COG0629	single-stranded DNA binding
MAP_RS11710	COG2937	Belongs to the GPAT DAPAT family
MAP_RS11725	COG0657	acetylesterase activity
MAP_RS11735	COG2801	Transposase and inactivated derivatives
MAP_RS11735	COG3415	Transposase
MAP_RS11760	COG0508	dehydrogenase complex catalyzes the overall conversion of
MAP_RS11780	COG2030	dehydratase
MAP_RS11785	COG1960	acyl-CoA dehydrogenase activity
MAP_RS11795	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MAP_RS11815	COG0300	oxidoreductase activity
MAP_RS11820	COG0433	COG0433 Predicted ATPase
MAP_RS11825	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
MAP_RS11840	COG1376	ErfK ybiS ycfS ynhG family protein
MAP_RS11850	COG2409	Drug exporters of the RND superfamily
MAP_RS11855	COG4552	Acetyltransferase involved in intracellular survival and related
MAP_RS11885	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MAP_RS11890	COG0736	holo-[acyl-carrier-protein] synthase activity
MAP_RS11900	COG3757	hydrolase, family 25
MAP_RS11950	COG2124	cytochrome p450
MAP_RS11980	COG1960	acyl-CoA dehydrogenase activity
MAP_RS11985	COG1960	acyl-CoA dehydrogenase activity
MAP_RS11990	COG1960	acyl-CoA dehydrogenase activity
MAP_RS11995	COG1960	acyl-CoA dehydrogenase activity
MAP_RS12020	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MAP_RS12035	COG1960	acyl-CoA dehydrogenase activity
MAP_RS12040	COG1960	acyl-CoA dehydrogenase activity
MAP_RS12045	COG0657	acetylesterase activity
MAP_RS12050	COG2124	cytochrome p450
MAP_RS12085	COG1309	transcriptional regulator
MAP_RS12100	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MAP_RS12120	COG2072	flavoprotein involved in K transport
MAP_RS12125	COG4638	Rieske (2fe-2S)
MAP_RS12150	COG2124	cytochrome p450
MAP_RS12160	COG0183	Belongs to the thiolase family
MAP_RS12165	COG1960	acyl-CoA dehydrogenase activity
MAP_RS12190	COG1024	Enoyl-CoA hydratase
MAP_RS12205	COG1028	Short-chain dehydrogenase reductase Sdr
MAP_RS12225	COG1024	Enoyl-CoA hydratase
MAP_RS12230	COG1024	Enoyl-CoA hydratase
MAP_RS12235	COG1024	Enoyl-CoA hydratase
MAP_RS12250	COG0318	PFAM AMP-dependent synthetase and ligase
MAP_RS12260	COG1802	Transcriptional regulator
MAP_RS12265	COG1960	acyl-CoA dehydrogenase activity
MAP_RS12270	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MAP_RS12275	COG0183	Belongs to the thiolase family
MAP_RS12285	COG1960	acyl-CoA dehydrogenase activity
MAP_RS12290	COG1028	Short-chain dehydrogenase reductase Sdr
MAP_RS12345	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MAP_RS12350	COG2123	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MAP_RS12355	COG1234	tRNA 3'-trailer cleavage
MAP_RS12360	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
MAP_RS12370	COG3191	aminopeptidase activity
MAP_RS12385	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MAP_RS12395	COG0058	SHG alpha-glucan phosphorylase activity
MAP_RS12405	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MAP_RS12420	COG0346	lactoylglutathione lyase activity
MAP_RS12445	COG2814	Major facilitator Superfamily
MAP_RS12450	COG0583	DNA-binding transcription factor activity
MAP_RS12465	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MAP_RS12490	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MAP_RS12525	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MAP_RS12525	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MAP_RS12535	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MAP_RS12540	COG0356	it plays a direct role in the translocation of protons across the membrane
MAP_RS12560	COG2890	protein-(glutamine-N5) methyltransferase activity
MAP_RS12565	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MAP_RS12580	COG0083	homoserine kinase activity
MAP_RS12590	COG0460	homoserine dehydrogenase
MAP_RS12600	COG0018	arginyl-trna synthetase
MAP_RS12635	COG0494	nUDIX hydrolase
MAP_RS12640	COG3631	Ketosteroid isomerase-related protein
MAP_RS12730	COG1403	HNH endonuclease
MAP_RS12815	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MAP_RS12835	COG0277	FAD linked oxidase domain protein
MAP_RS12885	COG1028	Short-chain dehydrogenase reductase Sdr
MAP_RS12895	COG1028	Short-chain dehydrogenase reductase Sdr
MAP_RS12905	COG1028	Short-chain dehydrogenase reductase Sdr
MAP_RS12935	COG0508	dehydrogenase complex catalyzes the overall conversion of
MAP_RS12935	COG0567	Dehydrogenase, E1 component
MAP_RS12960	COG0039	L-malate dehydrogenase activity
MAP_RS12965	COG0598	Magnesium transport protein CorA
MAP_RS13010	COG2239	Acts as a magnesium transporter
MAP_RS13030	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MAP_RS13035	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MAP_RS13040	COG5662	AntiSigma factor
MAP_RS13050	COG4122	O-methyltransferase activity
MAP_RS13055	COG1309	transcriptional regulator
MAP_RS13060	COG1131	(ABC) transporter
MAP_RS13065	COG3559	Exporter of polyketide antibiotics
MAP_RS13080	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MAP_RS13100	COG0519	Catalyzes the synthesis of GMP from XMP
MAP_RS13110	COG0463	Glycosyl transferase, family 2
MAP_RS13120	COG0318	PFAM AMP-dependent synthetase and ligase
MAP_RS13125	COG1611	Belongs to the LOG family
MAP_RS13160	COG0477	Major facilitator Superfamily
MAP_RS13165	COG0318	PFAM AMP-dependent synthetase and ligase
MAP_RS13175	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MAP_RS13185	COG2124	cytochrome p450
MAP_RS13190	COG1960	acyl-CoA dehydrogenase activity
MAP_RS13205	COG1960	acyl-CoA dehydrogenase activity
MAP_RS13225	COG0506	proline dehydrogenase activity
MAP_RS13230	COG1012	belongs to the aldehyde dehydrogenase family
MAP_RS13245	COG0318	PFAM AMP-dependent synthetase and ligase
MAP_RS13255	COG2046	Belongs to the sulfate adenylyltransferase family
MAP_RS13260	COG0529	Catalyzes the synthesis of activated sulfate
MAP_RS13290	COG0531	amino acid
MAP_RS13300	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
MAP_RS13305	COG2801	Transposase and inactivated derivatives
MAP_RS13305	COG3415	Transposase
MAP_RS13320	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
MAP_RS13330	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MAP_RS13345	COG1217	gtp-binding protein TYPA
MAP_RS13360	COG1140	nitrate reductase beta subunit
MAP_RS13380	COG2154	pterin-4-alpha-carbinolamine dehydratase
MAP_RS13410	COG3467	pyridoxamine 5'-phosphate
MAP_RS13425	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MAP_RS13435	COG2409	Drug exporters of the RND superfamily
MAP_RS13445	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MAP_RS13450	COG1024	Enoyl-CoA hydratase
MAP_RS13460	COG0702	epimerase
MAP_RS13480	COG1024	Enoyl-CoA hydratase
MAP_RS13485	COG0183	Belongs to the thiolase family
MAP_RS13495	COG2124	cytochrome p450
MAP_RS13500	COG1028	Short-chain dehydrogenase reductase Sdr
MAP_RS13515	COG0714	Associated with various cellular activities
MAP_RS13525	COG1960	acyl-CoA dehydrogenase activity
MAP_RS13530	COG1960	acyl-CoA dehydrogenase activity
MAP_RS13540	COG1309	transcriptional regulator
MAP_RS13555	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MAP_RS13570	COG0574	Belongs to the PEP-utilizing enzyme family
MAP_RS13570	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MAP_RS13600	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
MAP_RS13665	COG0012	GTP binding
MAP_RS13675	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MAP_RS13685	COG1570	exodeoxyribonuclease VII activity
MAP_RS13700	COG2272	Belongs to the type-B carboxylesterase lipase family
MAP_RS13740	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
MAP_RS13750	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MAP_RS13755	COG0572	uridine kinase
MAP_RS13785	COG1331	Highly conserved protein containing a thioredoxin domain
MAP_RS13795	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MAP_RS13800	COG1946	Acyl-CoA thioesterase
MAP_RS13835	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MAP_RS13840	COG0025	NhaP-type Na H and K H
MAP_RS13855	COG0667	Aldo Keto reductase
MAP_RS13860	COG4762	Protein conserved in bacteria
MAP_RS13865	COG2070	2-Nitropropane dioxygenase
MAP_RS13905	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MAP_RS13910	COG3485	protocatechuate 3,4-dioxygenase
MAP_RS13915	COG3485	protocatechuate 3,4-dioxygenase
MAP_RS13955	COG1414	Transcriptional regulator
MAP_RS13975	COG1366	Belongs to the anti-sigma-factor antagonist family
MAP_RS13985	COG0753	catalase activity
MAP_RS13990	COG1028	Short-chain dehydrogenase reductase Sdr
MAP_RS14005	COG1024	Enoyl-CoA hydratase
MAP_RS14045	COG4974	Belongs to the 'phage' integrase family
MAP_RS14175	COG4221	oxidoreductase activity
MAP_RS14205	COG1309	transcriptional regulator
MAP_RS14215	COG1028	Short-chain dehydrogenase reductase Sdr
MAP_RS14225	COG1012	belongs to the aldehyde dehydrogenase family
MAP_RS14290	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MAP_RS14315	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MAP_RS14335	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MAP_RS14345	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MAP_RS14350	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MAP_RS14355	COG0531	amino acid
MAP_RS14360	COG0569	domain protein
MAP_RS14410	COG0483	inositol monophosphate 1-phosphatase activity
MAP_RS14495	COG4044	May play a role in the intracellular transport of hydrophobic ligands
MAP_RS14505	COG1388	LysM domain
MAP_RS14510	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MAP_RS14525	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MAP_RS14530	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MAP_RS14535	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MAP_RS14550	COG1196	nuclear chromosome segregation
MAP_RS14560	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MAP_RS14595	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
MAP_RS14610	COG1842	Phage shock protein A
MAP_RS14625	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
MAP_RS14630	COG1674	ftsk spoiiie
MAP_RS14655	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MAP_RS14665	COG3214	Protein conserved in bacteria
MAP_RS14680	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MAP_RS14695	COG1028	Short-chain dehydrogenase reductase Sdr
MAP_RS14705	COG4770	biotin carboxylase activity
MAP_RS14710	COG0318	PFAM AMP-dependent synthetase and ligase
MAP_RS14730	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
MAP_RS14740	COG1403	HNH endonuclease
MAP_RS14780	COG0686	Belongs to the AlaDH PNT family
MAP_RS14795	COG1185	polyribonucleotide nucleotidyltransferase activity
MAP_RS14815	COG1960	acyl-CoA dehydrogenase activity
MAP_RS14820	COG0183	Belongs to the thiolase family
MAP_RS14825	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MAP_RS14830	COG2977	Belongs to the P-Pant transferase superfamily
MAP_RS14835	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
MAP_RS14860	COG1024	Enoyl-CoA hydratase
MAP_RS14870	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
MAP_RS14880	COG0481	GTPase activity
MAP_RS14895	COG0779	Required for maturation of 30S ribosomal subunits
MAP_RS14910	COG0442	prolyl-tRNA aminoacylation
MAP_RS14925	COG1648	precorrin-2 dehydrogenase activity
MAP_RS14925	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MAP_RS14950	COG0579	oxidoreductase
MAP_RS14965	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
MAP_RS14985	COG1028	Short-chain dehydrogenase reductase Sdr
MAP_RS14990	COG1012	belongs to the aldehyde dehydrogenase family
MAP_RS14995	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
MAP_RS15010	COG1492	cobalamin metabolic process
MAP_RS15035	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MAP_RS15040	COG0750	zinc metalloprotease
MAP_RS15045	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
MAP_RS15060	COG0820	rRNA (adenine-C2-)-methyltransferase activity
MAP_RS15065	COG0575	Belongs to the CDS family
MAP_RS15075	COG0528	UMP kinase activity
MAP_RS15085	COG0745	RESPONSE REGULATOR receiver
MAP_RS15100	COG1028	Short-chain dehydrogenase reductase Sdr
MAP_RS15115	COG0154	amidase activity
MAP_RS15120	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MAP_RS15125	COG0052	Belongs to the universal ribosomal protein uS2 family
MAP_RS15175	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
MAP_RS15185	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MAP_RS15205	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MAP_RS15225	COG0336	Belongs to the RNA methyltransferase TrmD family
MAP_RS15230	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MAP_RS15250	COG1686	Belongs to the peptidase S11 family
MAP_RS15285	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
MAP_RS15305	COG1196	nuclear chromosome segregation
MAP_RS15320	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MAP_RS15325	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
MAP_RS15330	COG0571	ribonuclease III activity
MAP_RS15350	COG0701	Predicted permease
MAP_RS15355	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
MAP_RS15370	COG0742	ribosomal rna small subunit methyltransferase
MAP_RS15385	COG0657	acetylesterase activity
MAP_RS15390	COG0656	L-ascorbic acid biosynthetic process
MAP_RS15405	COG1461	Dihydroxyacetone kinase
MAP_RS15445	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MAP_RS15460	COG1181	Belongs to the D-alanine--D-alanine ligase family
MAP_RS15465	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
MAP_RS15470	COG1920	GTP binding
MAP_RS15475	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MAP_RS15490	COG0066	3-isopropylmalate dehydratase activity
MAP_RS15495	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MAP_RS15520	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MAP_RS15525	COG0179	Fumarylacetoacetate (FAA) hydrolase
MAP_RS15530	COG2271	Major facilitator Superfamily
MAP_RS15535	COG0473	3-isopropylmalate dehydrogenase activity
MAP_RS15550	COG0655	NAD(P)H dehydrogenase (quinone) activity
MAP_RS15575	COG2259	Doxx family
MAP_RS15590	COG1192	Involved in chromosome partitioning
MAP_RS15595	COG0205	6-phosphofructokinase activity
MAP_RS15600	COG0154	amidase activity
MAP_RS15640	COG0626	cystathionine gamma-synthase activity
MAP_RS15660	COG0482	sulfurtransferase activity
MAP_RS15725	COG0142	geranyltranstransferase activity
MAP_RS15775	COG3415	Transposase
MAP_RS15775	COG2801	Transposase and inactivated derivatives
MAP_RS15780	COG1304	FMN binding
MAP_RS15785	COG2409	Drug exporters of the RND superfamily
MAP_RS15795	COG0415	Belongs to the DNA photolyase family
MAP_RS15800	COG0110	maltose O-acetyltransferase activity
MAP_RS15805	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MAP_RS15830	COG1024	Enoyl-CoA hydratase
MAP_RS15840	COG1119	ATPase activity
MAP_RS15850	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MAP_RS15870	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MAP_RS15875	COG2867	negative regulation of translational initiation
MAP_RS15875	COG2226	methyltransferase
MAP_RS15880	COG1309	transcriptional regulator
MAP_RS15885	COG2072	flavoprotein involved in K transport
MAP_RS15890	COG1309	transcriptional regulator
MAP_RS15950	COG2186	Transcriptional regulator
MAP_RS15965	COG1960	acyl-CoA dehydrogenase activity
MAP_RS15975	COG1793	dna ligase
MAP_RS15980	COG1966	Carbon starvation protein
MAP_RS15985	COG0443	Heat shock 70 kDa protein
MAP_RS15990	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MAP_RS15995	COG1024	Enoyl-CoA hydratase
MAP_RS16020	COG1028	Short-chain dehydrogenase reductase Sdr
MAP_RS16030	COG2076	Multidrug Resistance protein
MAP_RS16065	COG0148	phosphopyruvate hydratase activity
MAP_RS16075	COG2175	clavaminate synthase activity
MAP_RS16085	COG4638	Rieske (2fe-2S)
MAP_RS16090	COG1028	Short-chain dehydrogenase reductase Sdr
MAP_RS16115	COG4638	Rieske (2fe-2S)
MAP_RS16135	COG3654	unkown
MAP_RS16150	COG0477	Major facilitator Superfamily
MAP_RS16160	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MAP_RS16165	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MAP_RS16185	COG2301	Belongs to the HpcH HpaI aldolase family
MAP_RS16195	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
MAP_RS16225	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MAP_RS16250	COG1819	glycosyl
MAP_RS16275	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MAP_RS16280	COG2177	Part of the ABC transporter FtsEX involved in
MAP_RS16285	COG2884	Cell division ATP-binding protein ftsE
MAP_RS16295	COG0668	transmembrane transport
MAP_RS16305	COG0493	'glutamate synthase
MAP_RS16355	COG0483	inositol monophosphate 1-phosphatase activity
MAP_RS16365	COG1960	acyl-CoA dehydrogenase activity
MAP_RS16385	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MAP_RS16390	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MAP_RS16400	COG1960	acyl-CoA dehydrogenase activity
MAP_RS16440	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MAP_RS16465	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
MAP_RS16500	COG1309	transcriptional regulator
MAP_RS16505	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MAP_RS16520	COG0714	Associated with various cellular activities
MAP_RS16570	COG0477	Major facilitator Superfamily
MAP_RS16595	COG2201	protein-glutamate methylesterase activity
MAP_RS16610	COG2201	protein-glutamate methylesterase activity
MAP_RS16635	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MAP_RS16675	COG0297	glycogen (starch) synthase activity
MAP_RS16685	COG1088	dTDP-glucose 4,6-dehydratase activity
MAP_RS16690	COG2192	nodulation
MAP_RS16705	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
MAP_RS16710	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
MAP_RS16710	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
MAP_RS16715	COG1028	Short-chain dehydrogenase reductase Sdr
MAP_RS16725	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MAP_RS16730	COG0028	Belongs to the TPP enzyme family
MAP_RS16735	COG1573	uracil-dna glycosylase
MAP_RS16790	COG0789	Transcriptional regulator
MAP_RS16800	COG3707	response regulator
MAP_RS16825	COG4585	Histidine kinase
MAP_RS16830	COG2197	response regulator
MAP_RS16915	COG1615	UPF0182 protein
MAP_RS16920	COG3480	Lon protease (S16) C-terminal proteolytic domain
MAP_RS16935	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MAP_RS16960	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MAP_RS16965	COG0210	DNA helicase
MAP_RS16980	COG0596	Alpha beta hydrolase
MAP_RS17025	COG0513	Belongs to the DEAD box helicase family
MAP_RS17040	COG0406	alpha-ribazole phosphatase activity
MAP_RS17075	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MAP_RS17095	COG1063	alcohol dehydrogenase
MAP_RS17105	COG1028	Short-chain dehydrogenase reductase Sdr
MAP_RS17115	COG1028	Short-chain dehydrogenase reductase Sdr
MAP_RS17130	COG1403	HNH endonuclease
MAP_RS17140	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
MAP_RS17145	COG1162	GTPase activity
MAP_RS17150	COG1733	regulation of RNA biosynthetic process
MAP_RS17155	COG0183	Belongs to the thiolase family
MAP_RS17205	COG2326	polyphosphate kinase activity
MAP_RS17230	COG2020	methyltransferase activity
MAP_RS17235	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
MAP_RS17245	COG0653	protein targeting
MAP_RS17250	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MAP_RS17265	COG5401	PFAM Sporulation and spore germination
MAP_RS17270	COG5000	phosphorelay sensor kinase activity
MAP_RS17270	COG5002	protein histidine kinase activity
MAP_RS17285	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
MAP_RS17305	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MAP_RS17310	COG0531	amino acid
MAP_RS17315	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MAP_RS17320	COG1482	cell wall glycoprotein biosynthetic process
MAP_RS17330	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MAP_RS17355	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
MAP_RS17355	COG0778	Nitroreductase
MAP_RS17370	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
MAP_RS17385	COG1316	TRANSCRIPTIONal
MAP_RS17405	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MAP_RS17410	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MAP_RS17425	COG0784	Response regulator, receiver
MAP_RS17430	COG4251	negative regulation of phosphorylation
MAP_RS17470	COG1053	succinate dehydrogenase
MAP_RS17475	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MAP_RS17485	COG0424	maF-like protein
MAP_RS17500	COG4770	biotin carboxylase activity
MAP_RS17505	COG1366	Belongs to the anti-sigma-factor antagonist family
MAP_RS17535	COG1522	sequence-specific DNA binding
MAP_RS17545	COG1012	belongs to the aldehyde dehydrogenase family
MAP_RS17550	COG1309	transcriptional regulator
MAP_RS17555	COG1201	RNA secondary structure unwinding
MAP_RS17595	COG0564	pseudouridine synthase activity
MAP_RS17600	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MAP_RS17615	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
MAP_RS17615	COG1473	amidohydrolase
MAP_RS17620	COG1473	amidohydrolase
MAP_RS17635	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MAP_RS17645	COG3511	phospholipase C
MAP_RS17655	COG2304	oxidoreductase activity
MAP_RS17660	COG2304	oxidoreductase activity
MAP_RS17690	COG2009	succinate dehydrogenase
MAP_RS17705	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
MAP_RS17715	COG1595	DNA-templated transcription, initiation
MAP_RS17720	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MAP_RS17730	COG1686	Belongs to the peptidase S11 family
MAP_RS17735	COG2814	Major facilitator Superfamily
MAP_RS17750	COG1295	ribonuclease BN
MAP_RS17755	COG0180	Tryptophanyl-tRNA synthetase
MAP_RS17775	COG2873	o-acetylhomoserine
MAP_RS17780	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MAP_RS17805	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MAP_RS17815	COG0842	Transport permease protein
MAP_RS17815	COG1131	(ABC) transporter
MAP_RS17815	COG1716	ATPase activity
MAP_RS17820	COG1716	ATPase activity
MAP_RS17820	COG0842	Transport permease protein
MAP_RS17820	COG1131	(ABC) transporter
MAP_RS17830	COG1357	PFAM Pentapeptide repeats (8 copies)
MAP_RS17845	COG2018	Roadblock/LC7 domain
MAP_RS17850	COG5002	protein histidine kinase activity
MAP_RS17860	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
MAP_RS17870	COG0587	DNA-directed DNA polymerase activity
MAP_RS17880	COG1877	trehalose-phosphatase activity
MAP_RS17880	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MAP_RS17885	COG2030	dehydratase
MAP_RS17895	COG0406	alpha-ribazole phosphatase activity
MAP_RS17935	COG0519	Catalyzes the synthesis of GMP from XMP
MAP_RS17935	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MAP_RS17940	COG5651	PPE family
MAP_RS17980	COG0318	PFAM AMP-dependent synthetase and ligase
MAP_RS18005	COG1028	Short-chain dehydrogenase reductase Sdr
MAP_RS18010	COG0318	PFAM AMP-dependent synthetase and ligase
MAP_RS18025	COG1028	Short-chain dehydrogenase reductase Sdr
MAP_RS18035	COG2072	flavoprotein involved in K transport
MAP_RS18040	COG1028	Short-chain dehydrogenase reductase Sdr
MAP_RS18050	COG0028	Belongs to the TPP enzyme family
MAP_RS18060	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
MAP_RS18060	COG2755	lipolytic protein G-D-S-L family
MAP_RS18075	COG0604	alcohol dehydrogenase
MAP_RS18075	COG3321	synthase
MAP_RS18085	COG1376	ErfK ybiS ycfS ynhG family protein
MAP_RS18095	COG0583	DNA-binding transcription factor activity
MAP_RS18100	COG0028	Belongs to the TPP enzyme family
MAP_RS18120	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MAP_RS18130	COG3281	Trehalose synthase
MAP_RS18150	COG0842	Transport permease protein
MAP_RS18150	COG1129	ABC transporter
MAP_RS18165	COG1937	Protein conserved in bacteria
MAP_RS18175	COG2267	carboxylic ester hydrolase activity
MAP_RS18195	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MAP_RS18260	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MAP_RS18290	COG0783	Belongs to the Dps family
MAP_RS18295	COG1741	Belongs to the pirin family
MAP_RS18305	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MAP_RS18320	COG1012	belongs to the aldehyde dehydrogenase family
MAP_RS18325	COG1028	Short-chain dehydrogenase reductase Sdr
MAP_RS18330	COG2365	Tyrosine phosphatase family
MAP_RS18335	COG2365	Tyrosine phosphatase family
MAP_RS18365	COG1309	transcriptional regulator
MAP_RS18415	COG1960	acyl-CoA dehydrogenase activity
MAP_RS18440	COG2124	cytochrome p450
MAP_RS18460	COG2072	flavoprotein involved in K transport
MAP_RS18465	COG0657	acetylesterase activity
MAP_RS18485	COG1802	Transcriptional regulator
MAP_RS18495	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MAP_RS18525	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MAP_RS18540	COG1714	RDD family
MAP_RS18555	COG3619	membrane
MAP_RS18595	COG2267	carboxylic ester hydrolase activity
MAP_RS18610	COG1472	Belongs to the glycosyl hydrolase 3 family
MAP_RS18615	COG4122	O-methyltransferase activity
MAP_RS18630	COG0129	dihydroxy-acid dehydratase activity
MAP_RS18635	COG1937	Protein conserved in bacteria
MAP_RS18640	COG2814	Major facilitator Superfamily
MAP_RS18645	COG1376	ErfK ybiS ycfS ynhG family protein
MAP_RS18655	COG0243	molybdopterin cofactor binding
MAP_RS18680	COG2409	Drug exporters of the RND superfamily
MAP_RS18690	COG0220	tRNA (guanine-N7-)-methyltransferase activity
MAP_RS18705	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
MAP_RS18720	COG1024	Enoyl-CoA hydratase
MAP_RS18745	COG0657	acetylesterase activity
MAP_RS18750	COG0657	acetylesterase activity
MAP_RS18760	COG1024	Enoyl-CoA hydratase
MAP_RS18775	COG1309	transcriptional regulator
MAP_RS18785	COG0500	methyltransferase
MAP_RS18820	COG2801	Transposase and inactivated derivatives
MAP_RS18820	COG3415	Transposase
MAP_RS18830	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MAP_RS18835	COG1012	belongs to the aldehyde dehydrogenase family
MAP_RS18845	COG0028	Belongs to the TPP enzyme family
MAP_RS18850	COG0583	DNA-binding transcription factor activity
MAP_RS18900	COG4981	capsule polysaccharide biosynthetic process
MAP_RS18910	COG1472	Belongs to the glycosyl hydrolase 3 family
MAP_RS18925	COG2030	dehydratase
MAP_RS18930	COG1028	Short-chain dehydrogenase reductase Sdr
MAP_RS18935	COG0183	Belongs to the thiolase family
MAP_RS18945	COG1960	acyl-CoA dehydrogenase activity
MAP_RS18965	COG1053	succinate dehydrogenase
MAP_RS18985	COG2146	nitrite reductase [NAD(P)H] activity
MAP_RS18985	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MAP_RS19015	COG1984	allophanate hydrolase subunit 2
MAP_RS19020	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
MAP_RS19030	COG1309	transcriptional regulator
MAP_RS19035	COG2223	nitrite transmembrane transporter activity
MAP_RS19045	COG0318	PFAM AMP-dependent synthetase and ligase
MAP_RS19055	COG1960	acyl-CoA dehydrogenase activity
MAP_RS19070	COG0346	lactoylglutathione lyase activity
MAP_RS19105	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MAP_RS19110	COG1120	ATPase activity
MAP_RS19130	COG1129	ABC transporter
MAP_RS19150	COG1132	(ABC) transporter
MAP_RS19150	COG2375	cellular response to nickel ion
MAP_RS19165	COG0477	Major facilitator Superfamily
MAP_RS19170	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MAP_RS19170	COG3433	isochorismatase activity
MAP_RS19170	COG2226	methyltransferase
MAP_RS19175	COG3433	isochorismatase activity
MAP_RS19175	COG2226	methyltransferase
MAP_RS19175	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MAP_RS19180	COG3433	isochorismatase activity
MAP_RS19180	COG2226	methyltransferase
MAP_RS19180	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MAP_RS19185	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
MAP_RS19200	COG1937	Protein conserved in bacteria
MAP_RS19210	COG3547	Transposase (IS116 IS110 IS902 family)
MAP_RS19230	COG0318	PFAM AMP-dependent synthetase and ligase
MAP_RS19260	COG3328	transposase activity
MAP_RS19275	COG1819	glycosyl
MAP_RS19285	COG0604	alcohol dehydrogenase
MAP_RS19285	COG1028	Short-chain dehydrogenase reductase Sdr
MAP_RS19285	COG3321	synthase
MAP_RS19295	COG0701	Predicted permease
MAP_RS19305	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MAP_RS19310	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MAP_RS19315	COG0267	Belongs to the bacterial ribosomal protein bL33 family
MAP_RS19325	COG0254	rRNA binding
MAP_RS19335	COG0523	cobalamin synthesis protein
MAP_RS19345	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MAP_RS19350	COG1121	(ABC) transporter
MAP_RS19355	COG0803	Belongs to the bacterial solute-binding protein 9 family
MAP_RS19410	COG1404	Belongs to the peptidase S8 family
MAP_RS19435	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MAP_RS19440	COG0778	Nitroreductase
MAP_RS19470	COG1309	transcriptional regulator
MAP_RS19500	COG2130	NADP-dependent
MAP_RS19535	COG0246	Mannitol dehydrogenase
MAP_RS19555	COG1376	ErfK ybiS ycfS ynhG family protein
MAP_RS19580	COG2124	cytochrome p450
MAP_RS19595	COG0717	Belongs to the dCTP deaminase family
MAP_RS19620	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MAP_RS19650	COG0247	lactate metabolic process
MAP_RS19650	COG2181	nitrate reductase activity
MAP_RS19665	COG2814	Major facilitator Superfamily
MAP_RS19675	COG1511	domain protein
MAP_RS19695	COG0443	Heat shock 70 kDa protein
MAP_RS19700	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MAP_RS19705	COG0484	heat shock protein binding
MAP_RS19710	COG0789	Transcriptional regulator
MAP_RS19770	COG0542	response to heat
MAP_RS19775	COG2826	transposase and inactivated derivatives, IS30 family
MAP_RS19835	COG1994	Peptidase M50
MAP_RS19845	COG0406	alpha-ribazole phosphatase activity
MAP_RS19850	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MAP_RS19865	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MAP_RS19875	COG1252	NADH dehydrogenase
MAP_RS19890	COG1960	acyl-CoA dehydrogenase activity
MAP_RS19895	COG1960	acyl-CoA dehydrogenase activity
MAP_RS19900	COG1028	Short-chain dehydrogenase reductase Sdr
MAP_RS19910	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MAP_RS19920	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MAP_RS19935	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MAP_RS19960	COG1309	transcriptional regulator
MAP_RS19975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MAP_RS19990	COG0352	thiamine-phosphate diphosphorylase activity
MAP_RS19995	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
MAP_RS19995	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MAP_RS20005	COG2022	thiamine diphosphate biosynthetic process
MAP_RS20035	COG2234	aminopeptidase activity
MAP_RS20040	COG2234	aminopeptidase activity
MAP_RS20050	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MAP_RS20070	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MAP_RS20100	COG0242	peptide deformylase activity
MAP_RS20115	COG2032	superoxide dismutase activity
MAP_RS20150	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MAP_RS20165	COG0738	Major facilitator superfamily
MAP_RS20175	COG4221	oxidoreductase activity
MAP_RS20190	COG0459	protein refolding
MAP_RS20255	COG1024	Enoyl-CoA hydratase
MAP_RS20265	COG1505	serine-type exopeptidase activity
MAP_RS20325	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MAP_RS20340	COG2733	membrane
MAP_RS20365	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MAP_RS20385	COG0812	UDP-N-acetylmuramate dehydrogenase activity
MAP_RS20405	COG0438	transferase activity, transferring glycosyl groups
MAP_RS20415	COG0588	phosphoglycerate mutase activity
MAP_RS20490	COG2030	dehydratase
MAP_RS20530	COG0181	hydroxymethylbilane synthase activity
MAP_RS20555	COG1366	Belongs to the anti-sigma-factor antagonist family
MAP_RS20565	COG2755	lipolytic protein G-D-S-L family
MAP_RS20570	COG2755	lipolytic protein G-D-S-L family
MAP_RS20570	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
MAP_RS20595	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MAP_RS20600	COG4948	Mandelate Racemase Muconate Lactonizing
MAP_RS20615	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
MAP_RS20620	COG0406	alpha-ribazole phosphatase activity
MAP_RS20630	COG0785	Cytochrome C biogenesis protein
MAP_RS20640	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MAP_RS20645	COG2894	cell division
MAP_RS20655	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MAP_RS20665	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MAP_RS20715	COG0306	phosphate transporter
MAP_RS20725	COG4221	oxidoreductase activity
MAP_RS20740	COG0667	Aldo Keto reductase
MAP_RS20750	COG0318	PFAM AMP-dependent synthetase and ligase
MAP_RS20755	COG1228	amidohydrolase
MAP_RS20760	COG4948	Mandelate Racemase Muconate Lactonizing
MAP_RS20785	COG2226	methyltransferase
MAP_RS20800	COG0142	geranyltranstransferase activity
MAP_RS20805	COG0501	Belongs to the peptidase M48B family
MAP_RS20815	COG0659	secondary active sulfate transmembrane transporter activity
MAP_RS20820	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
MAP_RS20825	COG2072	flavoprotein involved in K transport
MAP_RS20830	COG1666	GTP binding
MAP_RS20840	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MAP_RS20845	COG1914	H( )-stimulated, divalent metal cation uptake system
MAP_RS20860	COG2124	cytochrome p450
MAP_RS20885	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MAP_RS20905	COG3537	Alpha-1,2-mannosidase
MAP_RS20915	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MAP_RS20945	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MAP_RS20950	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MAP_RS20975	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MAP_RS20990	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MAP_RS21000	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
MAP_RS21005	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MAP_RS21025	COG1752	Esterase of the alpha-beta hydrolase superfamily
MAP_RS21035	COG0243	molybdopterin cofactor binding
MAP_RS21050	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MAP_RS21075	COG2030	dehydratase
MAP_RS21080	COG2030	dehydratase
MAP_RS21085	COG2030	dehydratase
MAP_RS21095	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MAP_RS21115	COG4941	Belongs to the sigma-70 factor family
MAP_RS21125	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MAP_RS21130	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MAP_RS21135	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MAP_RS21145	COG2318	DinB family
MAP_RS21175	COG0222	ribosome binding
MAP_RS21200	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MAP_RS21210	COG1960	acyl-CoA dehydrogenase activity
MAP_RS21240	COG1309	transcriptional regulator
MAP_RS21280	COG1028	Short-chain dehydrogenase reductase Sdr
MAP_RS21290	COG0483	inositol monophosphate 1-phosphatase activity
MAP_RS21295	COG0656	L-ascorbic acid biosynthetic process
MAP_RS21315	COG0535	radical SAM domain protein
MAP_RS21360	COG0088	Forms part of the polypeptide exit tunnel
MAP_RS21370	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MAP_RS21385	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MAP_RS21400	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MAP_RS21420	COG1262	PFAM Formylglycine-generating sulfatase enzyme
MAP_RS21445	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MAP_RS21465	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MAP_RS21470	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MAP_RS21485	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MAP_RS21490	COG0616	signal peptide processing
MAP_RS21495	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MAP_RS21500	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MAP_RS21505	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MAP_RS21510	COG1063	alcohol dehydrogenase
MAP_RS21520	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MAP_RS21535	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MAP_RS21545	COG0563	adenylate kinase activity
MAP_RS21565	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MAP_RS21580	COG0577	efflux transmembrane transporter activity
MAP_RS21585	COG0577	efflux transmembrane transporter activity
MAP_RS21585	COG1136	(ABC) transporter
MAP_RS21600	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MAP_RS21605	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MAP_RS21620	COG1960	acyl-CoA dehydrogenase activity
MAP_RS21645	COG3794	PFAM blue (type 1) copper domain protein
MAP_RS21695	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MAP_RS21720	COG0203	ribosomal protein L17
MAP_RS21725	COG0101	tRNA pseudouridine synthase activity
MAP_RS21745	COG1404	Belongs to the peptidase S8 family
MAP_RS21755	COG1674	ftsk spoiiie
MAP_RS21765	COG4842	Belongs to the WXG100 family
MAP_RS21770	COG4842	Belongs to the WXG100 family
MAP_RS21780	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
MAP_RS21785	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MAP_RS21800	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MAP_RS21815	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
MAP_RS21835	COG0076	glutamate decarboxylase activity
MAP_RS21860	COG0456	acetyltransferase
MAP_RS21875	COG0459	protein refolding
MAP_RS21885	COG1396	sequence-specific DNA binding
MAP_RS21890	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
MAP_RS21900	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MAP_RS21905	COG2032	superoxide dismutase activity
MAP_RS21955	COG1028	Short-chain dehydrogenase reductase Sdr
MAP_RS22000	COG1309	transcriptional regulator
MAP_RS22005	COG0596	Alpha beta hydrolase
MAP_RS22010	COG1028	Short-chain dehydrogenase reductase Sdr
MAP_RS22015	COG0318	PFAM AMP-dependent synthetase and ligase
MAP_RS22040	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MAP_RS22050	COG1609	Transcriptional regulator
MAP_RS22070	COG1960	acyl-CoA dehydrogenase activity
MAP_RS22075	COG1309	transcriptional regulator
MAP_RS22095	COG3588	fructose-bisphosphate aldolase
MAP_RS22125	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
MAP_RS22130	COG4638	Rieske (2fe-2S)
MAP_RS22140	COG2197	response regulator
MAP_RS22145	COG4585	Histidine kinase
MAP_RS22160	COG1674	ftsk spoiiie
MAP_RS22245	COG1595	DNA-templated transcription, initiation
MAP_RS22265	COG3409	Peptidoglycan-binding domain 1 protein
MAP_RS22265	COG0860	N-Acetylmuramoyl-L-alanine amidase
MAP_RS22280	COG1192	Involved in chromosome partitioning
MAP_RS22290	COG0357	Ribosomal RNA small subunit methyltransferase G
MAP_RS22300	COG0706	membrane insertase activity
MAP_RS22305	COG0594	ribonuclease P activity
MAP_RS22315	COG0028	Belongs to the TPP enzyme family