locus-tag	class	description
EGM64_RS00005	COG0318	PFAM AMP-dependent synthetase and ligase
EGM64_RS00010	COG1028	Short-chain dehydrogenase reductase Sdr
EGM64_RS00020	COG1309	transcriptional regulator
EGM64_RS00065	COG1028	Short-chain dehydrogenase reductase Sdr
EGM64_RS00115	COG2032	superoxide dismutase activity
EGM64_RS00130	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
EGM64_RS00135	COG1396	sequence-specific DNA binding
EGM64_RS00150	COG0459	protein refolding
EGM64_RS00165	COG0456	acetyltransferase
EGM64_RS00190	COG0076	glutamate decarboxylase activity
EGM64_RS00210	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EGM64_RS00225	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGM64_RS00240	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EGM64_RS00245	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EGM64_RS00255	COG4842	Belongs to the WXG100 family
EGM64_RS00260	COG4842	Belongs to the WXG100 family
EGM64_RS00270	COG1674	ftsk spoiiie
EGM64_RS00280	COG1404	Belongs to the peptidase S8 family
EGM64_RS00300	COG0101	tRNA pseudouridine synthase activity
EGM64_RS00305	COG0203	ribosomal protein L17
EGM64_RS00330	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EGM64_RS00335	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EGM64_RS00385	COG3794	PFAM blue (type 1) copper domain protein
EGM64_RS00410	COG1960	acyl-CoA dehydrogenase activity
EGM64_RS00425	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EGM64_RS00430	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EGM64_RS00445	COG0577	efflux transmembrane transporter activity
EGM64_RS00445	COG1136	(ABC) transporter
EGM64_RS00450	COG0577	efflux transmembrane transporter activity
EGM64_RS00465	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EGM64_RS00485	COG0563	adenylate kinase activity
EGM64_RS00495	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EGM64_RS00510	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EGM64_RS00520	COG1063	alcohol dehydrogenase
EGM64_RS00530	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EGM64_RS00535	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EGM64_RS00540	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EGM64_RS00545	COG0616	signal peptide processing
EGM64_RS00550	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGM64_RS00565	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EGM64_RS00570	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EGM64_RS00590	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EGM64_RS00615	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EGM64_RS00635	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EGM64_RS00650	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EGM64_RS00665	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EGM64_RS00675	COG0088	Forms part of the polypeptide exit tunnel
EGM64_RS00720	COG0535	radical SAM domain protein
EGM64_RS00740	COG0656	L-ascorbic acid biosynthetic process
EGM64_RS00745	COG0483	inositol monophosphate 1-phosphatase activity
EGM64_RS00755	COG1028	Short-chain dehydrogenase reductase Sdr
EGM64_RS00790	COG1309	transcriptional regulator
EGM64_RS00820	COG1960	acyl-CoA dehydrogenase activity
EGM64_RS00830	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EGM64_RS00855	COG0222	ribosome binding
EGM64_RS00885	COG2318	DinB family
EGM64_RS00895	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EGM64_RS00900	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EGM64_RS00905	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EGM64_RS00915	COG4941	Belongs to the sigma-70 factor family
EGM64_RS00935	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EGM64_RS00945	COG2030	dehydratase
EGM64_RS00950	COG2030	dehydratase
EGM64_RS00955	COG2030	dehydratase
EGM64_RS00980	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EGM64_RS00995	COG0243	molybdopterin cofactor binding
EGM64_RS01005	COG1752	Esterase of the alpha-beta hydrolase superfamily
EGM64_RS01025	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EGM64_RS01030	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
EGM64_RS01040	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EGM64_RS01055	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EGM64_RS01080	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EGM64_RS01085	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EGM64_RS01115	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EGM64_RS01125	COG3537	Alpha-1,2-mannosidase
EGM64_RS01145	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EGM64_RS01170	COG2124	cytochrome p450
EGM64_RS01190	COG1914	H( )-stimulated, divalent metal cation uptake system
EGM64_RS01195	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EGM64_RS01210	COG1666	GTP binding
EGM64_RS01215	COG2072	flavoprotein involved in K transport
EGM64_RS01220	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EGM64_RS01225	COG0659	secondary active sulfate transmembrane transporter activity
EGM64_RS01235	COG0501	Belongs to the peptidase M48B family
EGM64_RS01240	COG0142	geranyltranstransferase activity
EGM64_RS01255	COG2226	methyltransferase
EGM64_RS01285	COG4948	Mandelate Racemase Muconate Lactonizing
EGM64_RS01290	COG1228	amidohydrolase
EGM64_RS01295	COG0318	PFAM AMP-dependent synthetase and ligase
EGM64_RS01305	COG0667	Aldo Keto reductase
EGM64_RS01320	COG4221	oxidoreductase activity
EGM64_RS01330	COG0306	phosphate transporter
EGM64_RS01375	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EGM64_RS01380	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EGM64_RS01390	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EGM64_RS01405	COG2894	cell division
EGM64_RS01410	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EGM64_RS01420	COG0785	Cytochrome C biogenesis protein
EGM64_RS01430	COG0406	alpha-ribazole phosphatase activity
EGM64_RS01435	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EGM64_RS01450	COG4948	Mandelate Racemase Muconate Lactonizing
EGM64_RS01455	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EGM64_RS01485	COG2755	lipolytic protein G-D-S-L family
EGM64_RS01485	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EGM64_RS01490	COG2755	lipolytic protein G-D-S-L family
EGM64_RS01500	COG1366	Belongs to the anti-sigma-factor antagonist family
EGM64_RS01525	COG0181	hydroxymethylbilane synthase activity
EGM64_RS01580	COG2030	dehydratase
EGM64_RS01660	COG0588	phosphoglycerate mutase activity
EGM64_RS01670	COG0438	transferase activity, transferring glycosyl groups
EGM64_RS01695	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EGM64_RS01715	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EGM64_RS01745	COG2733	membrane
EGM64_RS01760	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EGM64_RS01820	COG1505	serine-type exopeptidase activity
EGM64_RS01830	COG1024	Enoyl-CoA hydratase
EGM64_RS01895	COG0459	protein refolding
EGM64_RS01910	COG4221	oxidoreductase activity
EGM64_RS01920	COG0738	Major facilitator superfamily
EGM64_RS01925	COG0688	phosphatidylethanolamine metabolic process
EGM64_RS01935	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EGM64_RS01970	COG2032	superoxide dismutase activity
EGM64_RS01985	COG0242	peptide deformylase activity
EGM64_RS02015	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EGM64_RS02035	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGM64_RS02045	COG2234	aminopeptidase activity
EGM64_RS02050	COG2234	aminopeptidase activity
EGM64_RS02080	COG2022	thiamine diphosphate biosynthetic process
EGM64_RS02090	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EGM64_RS02090	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
EGM64_RS02095	COG0352	thiamine-phosphate diphosphorylase activity
EGM64_RS02110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EGM64_RS02125	COG1309	transcriptional regulator
EGM64_RS02150	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EGM64_RS02165	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EGM64_RS02175	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EGM64_RS02185	COG1028	Short-chain dehydrogenase reductase Sdr
EGM64_RS02190	COG1960	acyl-CoA dehydrogenase activity
EGM64_RS02195	COG1960	acyl-CoA dehydrogenase activity
EGM64_RS02220	COG1252	NADH dehydrogenase
EGM64_RS02230	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EGM64_RS02245	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EGM64_RS02250	COG0406	alpha-ribazole phosphatase activity
EGM64_RS02260	COG1994	Peptidase M50
EGM64_RS02320	COG2826	transposase and inactivated derivatives, IS30 family
EGM64_RS02325	COG0542	response to heat
EGM64_RS02385	COG0789	Transcriptional regulator
EGM64_RS02390	COG0484	heat shock protein binding
EGM64_RS02395	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EGM64_RS02400	COG0443	Heat shock 70 kDa protein
EGM64_RS02420	COG1511	domain protein
EGM64_RS02430	COG2814	Major facilitator Superfamily
EGM64_RS02445	COG2181	nitrate reductase activity
EGM64_RS02445	COG0247	lactate metabolic process
EGM64_RS02475	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EGM64_RS02500	COG0717	Belongs to the dCTP deaminase family
EGM64_RS02515	COG2124	cytochrome p450
EGM64_RS02555	COG1376	ErfK ybiS ycfS ynhG family protein
EGM64_RS02575	COG0246	Mannitol dehydrogenase
EGM64_RS02610	COG2130	NADP-dependent
EGM64_RS02640	COG1309	transcriptional regulator
EGM64_RS02670	COG0778	Nitroreductase
EGM64_RS02675	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EGM64_RS02695	COG1404	Belongs to the peptidase S8 family
EGM64_RS02750	COG0803	Belongs to the bacterial solute-binding protein 9 family
EGM64_RS02755	COG1121	(ABC) transporter
EGM64_RS02760	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EGM64_RS02770	COG0523	cobalamin synthesis protein
EGM64_RS02780	COG0254	rRNA binding
EGM64_RS02795	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EGM64_RS02800	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EGM64_RS02805	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EGM64_RS02815	COG0701	Predicted permease
EGM64_RS02825	COG3321	synthase
EGM64_RS02825	COG1028	Short-chain dehydrogenase reductase Sdr
EGM64_RS02825	COG0604	alcohol dehydrogenase
EGM64_RS02835	COG1819	glycosyl
EGM64_RS02850	COG3328	transposase activity
EGM64_RS02900	COG0515	serine threonine protein kinase
EGM64_RS02925	COG1716	ATPase activity
EGM64_RS02965	COG3328	transposase activity
EGM64_RS03000	COG1960	acyl-CoA dehydrogenase activity
EGM64_RS03025	COG0791	NLP P60 protein
EGM64_RS03025	COG0741	lytic transglycosylase activity
EGM64_RS03085	COG0495	leucyl-tRNA aminoacylation
EGM64_RS03105	COG0765	amino acid transport
EGM64_RS03120	COG0596	Alpha beta hydrolase
EGM64_RS03120	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EGM64_RS03165	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EGM64_RS03180	COG0360	Binds together with S18 to 16S ribosomal RNA
EGM64_RS03195	COG0359	binds to the 23S rRNA
EGM64_RS03205	COG0204	Acyl-transferase
EGM64_RS03215	COG1309	transcriptional regulator
EGM64_RS03245	COG1028	Short-chain dehydrogenase reductase Sdr
EGM64_RS03255	COG0277	FAD linked oxidase domain protein
EGM64_RS03295	COG1247	-acetyltransferase
EGM64_RS03315	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EGM64_RS03325	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EGM64_RS03380	COG3328	transposase activity
EGM64_RS03395	COG4974	Belongs to the 'phage' integrase family
EGM64_RS03445	COG1309	transcriptional regulator
EGM64_RS03495	COG0659	secondary active sulfate transmembrane transporter activity
EGM64_RS03500	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGM64_RS03505	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EGM64_RS03525	COG0477	Major facilitator Superfamily
EGM64_RS03535	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EGM64_RS03540	COG0346	lactoylglutathione lyase activity
EGM64_RS03565	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGM64_RS03580	COG1116	anion transmembrane transporter activity
EGM64_RS03585	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EGM64_RS03590	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EGM64_RS03605	COG1960	acyl-CoA dehydrogenase activity
EGM64_RS03620	COG1024	Enoyl-CoA hydratase
EGM64_RS03625	COG1309	transcriptional regulator
EGM64_RS03680	COG1404	Belongs to the peptidase S8 family
EGM64_RS03715	COG0070	glutamate synthase
EGM64_RS03715	COG0069	glutamate synthase activity
EGM64_RS03715	COG0067	glutamate synthase
EGM64_RS03735	COG1796	DNA polymerase
EGM64_RS03735	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EGM64_RS03740	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EGM64_RS03745	COG1309	transcriptional regulator
EGM64_RS03750	COG2072	flavoprotein involved in K transport
EGM64_RS03755	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EGM64_RS03805	COG1316	TRANSCRIPTIONal
EGM64_RS03840	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EGM64_RS03895	COG0561	phosphatase activity
EGM64_RS03915	COG1216	Glycosyl transferase, family 2
EGM64_RS03930	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EGM64_RS03940	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
EGM64_RS03945	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
EGM64_RS03950	COG0318	PFAM AMP-dependent synthetase and ligase
EGM64_RS03955	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EGM64_RS03955	COG3321	synthase
EGM64_RS03955	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
EGM64_RS03960	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EGM64_RS03975	COG1960	acyl-CoA dehydrogenase activity
EGM64_RS04030	COG1028	Short-chain dehydrogenase reductase Sdr
EGM64_RS04035	COG0277	FAD linked oxidase domain protein
EGM64_RS04085	COG0604	alcohol dehydrogenase
EGM64_RS04105	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EGM64_RS04125	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EGM64_RS04140	COG3415	Transposase
EGM64_RS04140	COG2801	Transposase and inactivated derivatives
EGM64_RS04155	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EGM64_RS04170	COG0745	RESPONSE REGULATOR receiver
EGM64_RS04180	COG2205	protein histidine kinase activity
EGM64_RS04190	COG2015	COG2015, Alkyl sulfatase and related hydrolases
EGM64_RS04235	COG5416	Lipopolysaccharide assembly protein A domain
EGM64_RS04250	COG1174	glycine betaine transport
EGM64_RS04265	COG0287	Prephenate dehydrogenase
EGM64_RS04275	COG0590	tRNA wobble adenosine to inosine editing
EGM64_RS04350	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EGM64_RS04355	COG2301	Belongs to the HpcH HpaI aldolase family
EGM64_RS04370	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EGM64_RS04380	COG1396	sequence-specific DNA binding
EGM64_RS04380	COG3800	Transcriptional regulator
EGM64_RS04385	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EGM64_RS04405	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EGM64_RS04415	COG0121	glutamine amidotransferase
EGM64_RS04465	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EGM64_RS04480	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EGM64_RS04495	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EGM64_RS04500	COG0860	N-Acetylmuramoyl-L-alanine amidase
EGM64_RS04515	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EGM64_RS04525	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EGM64_RS04580	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EGM64_RS04625	COG1793	dna ligase
EGM64_RS04640	COG2124	cytochrome p450
EGM64_RS04645	COG0596	Alpha beta hydrolase
EGM64_RS04665	COG3804	dihydrodipicolinate reductase
EGM64_RS04685	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EGM64_RS04695	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EGM64_RS04700	COG1695	Transcriptional regulator
EGM64_RS04725	COG0714	Associated with various cellular activities
EGM64_RS04765	COG0709	Synthesizes selenophosphate from selenide and ATP
EGM64_RS04770	COG3383	formate dehydrogenase (NAD+) activity
EGM64_RS04770	COG0243	molybdopterin cofactor binding
EGM64_RS04775	COG0243	molybdopterin cofactor binding
EGM64_RS04775	COG3383	formate dehydrogenase (NAD+) activity
EGM64_RS04780	COG0437	4 iron, 4 sulfur cluster binding
EGM64_RS04790	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGM64_RS04795	COG0693	protein deglycase activity
EGM64_RS04800	COG2890	protein-(glutamine-N5) methyltransferase activity
EGM64_RS04830	COG2172	sigma factor antagonist activity
EGM64_RS04835	COG1366	Belongs to the anti-sigma-factor antagonist family
EGM64_RS04840	COG1366	Belongs to the anti-sigma-factor antagonist family
EGM64_RS04900	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EGM64_RS04905	COG1408	metallophosphoesterase
EGM64_RS04940	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EGM64_RS04955	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EGM64_RS04990	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EGM64_RS05005	COG0601	transmembrane transport
EGM64_RS05010	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EGM64_RS05075	COG1111	helicase
EGM64_RS05075	COG1205	dead DEAH box helicase
EGM64_RS05100	COG0470	DNA polymerase III
EGM64_RS05110	COG2801	Transposase and inactivated derivatives
EGM64_RS05110	COG3415	Transposase
EGM64_RS05130	COG1215	transferase activity, transferring glycosyl groups
EGM64_RS05150	COG2027	D-alanyl-D-alanine carboxypeptidase
EGM64_RS05160	COG0037	tRNA processing
EGM64_RS05175	COG3391	amine dehydrogenase activity
EGM64_RS05190	COG1063	alcohol dehydrogenase
EGM64_RS05200	COG2267	carboxylic ester hydrolase activity
EGM64_RS05215	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EGM64_RS05220	COG0302	gtp cyclohydrolase
EGM64_RS05225	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EGM64_RS05255	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EGM64_RS05335	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
EGM64_RS05355	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EGM64_RS05365	COG0215	cysteine-tRNA ligase activity
EGM64_RS05370	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EGM64_RS05380	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EGM64_RS05400	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EGM64_RS05405	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EGM64_RS05410	COG1121	(ABC) transporter
EGM64_RS05420	COG1609	Transcriptional regulator
EGM64_RS05425	COG1309	transcriptional regulator
EGM64_RS05430	COG1960	acyl-CoA dehydrogenase activity
EGM64_RS05480	COG0436	Aminotransferase
EGM64_RS05485	COG1960	acyl-CoA dehydrogenase activity
EGM64_RS05490	COG1960	acyl-CoA dehydrogenase activity
EGM64_RS05495	COG1960	acyl-CoA dehydrogenase activity
EGM64_RS05505	COG1960	acyl-CoA dehydrogenase activity
EGM64_RS05510	COG1028	Short-chain dehydrogenase reductase Sdr
EGM64_RS05520	COG0183	Belongs to the thiolase family
EGM64_RS05550	COG1024	Enoyl-CoA hydratase
EGM64_RS05555	COG1028	Short-chain dehydrogenase reductase Sdr
EGM64_RS05560	COG1028	Short-chain dehydrogenase reductase Sdr
EGM64_RS05575	COG0183	Belongs to the thiolase family
EGM64_RS05580	COG2124	cytochrome p450
EGM64_RS05585	COG1960	acyl-CoA dehydrogenase activity
EGM64_RS05590	COG1960	acyl-CoA dehydrogenase activity
EGM64_RS05595	COG2030	dehydratase
EGM64_RS05615	COG2030	dehydratase
EGM64_RS05620	COG1053	succinate dehydrogenase
EGM64_RS05625	COG3971	2-oxopent-4-enoate hydratase activity
EGM64_RS05630	COG4569	acetaldehyde dehydrogenase (acetylating) activity
EGM64_RS05635	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EGM64_RS05665	COG4638	Rieske (2fe-2S)
EGM64_RS05680	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EGM64_RS05695	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGM64_RS05705	COG2124	cytochrome p450
EGM64_RS05715	COG1024	Enoyl-CoA hydratase
EGM64_RS05725	COG3001	Fructosamine kinase
EGM64_RS05750	COG0318	PFAM AMP-dependent synthetase and ligase
EGM64_RS05760	COG1960	acyl-CoA dehydrogenase activity
EGM64_RS05770	COG1028	Short-chain dehydrogenase reductase Sdr
EGM64_RS05780	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EGM64_RS05805	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EGM64_RS05830	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
EGM64_RS05840	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EGM64_RS05845	COG0390	transport system, permease component
EGM64_RS05850	COG1024	Enoyl-CoA hydratase
EGM64_RS05865	COG1316	TRANSCRIPTIONal
EGM64_RS05875	COG0154	amidase activity
EGM64_RS05915	COG2801	Transposase and inactivated derivatives
EGM64_RS05915	COG3415	Transposase
EGM64_RS05930	COG0745	RESPONSE REGULATOR receiver
EGM64_RS05935	COG2205	protein histidine kinase activity
EGM64_RS05965	COG2124	cytochrome p450
EGM64_RS05970	COG4221	oxidoreductase activity
EGM64_RS06030	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EGM64_RS06045	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EGM64_RS06065	COG0477	Major facilitator Superfamily
EGM64_RS06070	COG0477	Major facilitator Superfamily
EGM64_RS06085	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EGM64_RS06095	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EGM64_RS06100	COG0047	phosphoribosylformylglycinamidine synthase activity
EGM64_RS06125	COG2837	iron assimilation
EGM64_RS06145	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EGM64_RS06165	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EGM64_RS06175	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EGM64_RS06185	COG4044	May play a role in the intracellular transport of hydrophobic ligands
EGM64_RS06205	COG3118	belongs to the thioredoxin family
EGM64_RS06215	COG0745	RESPONSE REGULATOR receiver
EGM64_RS06240	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EGM64_RS06290	COG0640	Transcriptional regulator
EGM64_RS06295	COG0590	tRNA wobble adenosine to inosine editing
EGM64_RS06300	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EGM64_RS06305	COG2801	Transposase and inactivated derivatives
EGM64_RS06305	COG3415	Transposase
EGM64_RS06330	COG1028	Short-chain dehydrogenase reductase Sdr
EGM64_RS06345	COG2124	cytochrome p450
EGM64_RS06375	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EGM64_RS06375	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EGM64_RS06380	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EGM64_RS06385	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGM64_RS06390	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EGM64_RS06405	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EGM64_RS06415	COG1960	acyl-CoA dehydrogenase activity
EGM64_RS06420	COG1960	acyl-CoA dehydrogenase activity
EGM64_RS06430	COG0596	Alpha beta hydrolase
EGM64_RS06435	COG3479	Phenolic acid decarboxylase
EGM64_RS06440	COG0183	Belongs to the thiolase family
EGM64_RS06450	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EGM64_RS06460	COG4585	Histidine kinase
EGM64_RS06465	COG1053	succinate dehydrogenase
EGM64_RS06475	COG2267	carboxylic ester hydrolase activity
EGM64_RS06480	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EGM64_RS06485	COG3384	dioxygenase
EGM64_RS06490	COG1053	succinate dehydrogenase
EGM64_RS06500	COG1028	Short-chain dehydrogenase reductase Sdr
EGM64_RS06515	COG2132	Multicopper oxidase
EGM64_RS06555	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EGM64_RS06560	COG1028	Short-chain dehydrogenase reductase Sdr
EGM64_RS06570	COG1028	Short-chain dehydrogenase reductase Sdr
EGM64_RS06580	COG1960	acyl-CoA dehydrogenase activity
EGM64_RS06595	COG1960	acyl-CoA dehydrogenase activity
EGM64_RS06605	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EGM64_RS06615	COG4638	Rieske (2fe-2S)
EGM64_RS06635	COG0183	Belongs to the thiolase family
EGM64_RS06640	COG1309	transcriptional regulator
EGM64_RS06650	COG2124	cytochrome p450
EGM64_RS06670	COG2124	cytochrome p450
EGM64_RS06715	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
EGM64_RS06755	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
EGM64_RS06755	COG0778	Nitroreductase
EGM64_RS06760	COG1960	acyl-CoA dehydrogenase activity
EGM64_RS06765	COG1960	acyl-CoA dehydrogenase activity
EGM64_RS06810	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EGM64_RS06815	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EGM64_RS06820	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EGM64_RS06845	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EGM64_RS06875	COG1309	transcriptional regulator
EGM64_RS06905	COG1309	transcriptional regulator
EGM64_RS06915	COG1024	Enoyl-CoA hydratase
EGM64_RS06930	COG0318	PFAM AMP-dependent synthetase and ligase
EGM64_RS06945	COG3961	Belongs to the TPP enzyme family
EGM64_RS06955	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EGM64_RS06975	COG0183	Belongs to the thiolase family
EGM64_RS06980	COG1024	Enoyl-CoA hydratase
EGM64_RS06980	COG1250	3-hydroxyacyl-CoA dehydrogenase
EGM64_RS07005	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGM64_RS07020	COG0183	Belongs to the thiolase family
EGM64_RS07025	COG1061	Type III restriction enzyme res subunit
EGM64_RS07045	COG0521	Mo-molybdopterin cofactor biosynthetic process
EGM64_RS07070	COG3304	Inner membrane component domain
EGM64_RS07075	COG1278	Cold shock
EGM64_RS07085	COG0435	Glutathione S-transferase
EGM64_RS07100	COG2814	Major facilitator Superfamily
EGM64_RS07140	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EGM64_RS07165	COG0259	pyridoxamine-phosphate oxidase activity
EGM64_RS07185	COG3547	Transposase (IS116 IS110 IS902 family)
EGM64_RS07195	COG0745	RESPONSE REGULATOR receiver
EGM64_RS07205	COG0438	transferase activity, transferring glycosyl groups
EGM64_RS07215	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EGM64_RS07285	COG3328	transposase activity
EGM64_RS07290	COG3415	Transposase
EGM64_RS07290	COG2801	Transposase and inactivated derivatives
EGM64_RS07390	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGM64_RS07440	COG0246	Mannitol dehydrogenase
EGM64_RS07445	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EGM64_RS07465	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EGM64_RS07500	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EGM64_RS07510	COG0166	Belongs to the GPI family
EGM64_RS07530	COG4942	peptidase
EGM64_RS07570	COG0138	bifunctional purine biosynthesis protein purh
EGM64_RS07600	COG1024	Enoyl-CoA hydratase
EGM64_RS07615	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EGM64_RS07620	COG1960	acyl-CoA dehydrogenase activity
EGM64_RS07640	COG2205	protein histidine kinase activity
EGM64_RS07650	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EGM64_RS07655	COG0521	Mo-molybdopterin cofactor biosynthetic process
EGM64_RS07655	COG0315	cyclic pyranopterin monophosphate synthase activity
EGM64_RS07660	COG1970	mechanosensitive ion channel activity
EGM64_RS07675	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EGM64_RS07680	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EGM64_RS07730	COG4638	Rieske (2fe-2S)
EGM64_RS07745	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
EGM64_RS07750	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EGM64_RS07755	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EGM64_RS07755	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EGM64_RS07790	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EGM64_RS07835	COG0438	transferase activity, transferring glycosyl groups
EGM64_RS07835	COG0297	glycogen (starch) synthase activity
EGM64_RS07875	COG0297	glycogen (starch) synthase activity
EGM64_RS07890	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
EGM64_RS07940	COG0084	hydrolase, TatD family'
EGM64_RS07950	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EGM64_RS07955	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EGM64_RS07965	COG0318	PFAM AMP-dependent synthetase and ligase
EGM64_RS07970	COG0193	aminoacyl-tRNA hydrolase activity
EGM64_RS07975	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EGM64_RS07990	COG1393	Belongs to the ArsC family
EGM64_RS08000	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EGM64_RS08025	COG3956	TIGRFAM MazG family protein
EGM64_RS08070	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
EGM64_RS08080	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EGM64_RS08095	COG2205	protein histidine kinase activity
EGM64_RS08100	COG0745	RESPONSE REGULATOR receiver
EGM64_RS08145	COG3391	amine dehydrogenase activity
EGM64_RS08160	COG0121	glutamine amidotransferase
EGM64_RS08200	COG1024	Enoyl-CoA hydratase
EGM64_RS08215	COG2755	lipolytic protein G-D-S-L family
EGM64_RS08220	COG0657	acetylesterase activity
EGM64_RS08260	COG0217	transcriptional regulatory protein
EGM64_RS08270	COG3766	membrane
EGM64_RS08320	COG3320	Male sterility
EGM64_RS08320	COG1022	Amp-dependent synthetase and ligase
EGM64_RS08335	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EGM64_RS08340	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EGM64_RS08345	COG0747	negative chemotaxis
EGM64_RS08350	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EGM64_RS08355	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EGM64_RS08360	COG3415	Transposase
EGM64_RS08360	COG2801	Transposase and inactivated derivatives
EGM64_RS08375	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EGM64_RS08380	COG0124	histidyl-tRNA synthetase
EGM64_RS08390	COG1403	HNH endonuclease
EGM64_RS08415	COG1396	sequence-specific DNA binding
EGM64_RS08420	COG0235	Class ii aldolase
EGM64_RS08425	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EGM64_RS08445	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EGM64_RS08520	COG0432	Pfam Uncharacterised protein family UPF0047
EGM64_RS08530	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EGM64_RS08535	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EGM64_RS08540	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EGM64_RS08550	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGM64_RS08555	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGM64_RS08580	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EGM64_RS08590	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EGM64_RS08600	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EGM64_RS08605	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EGM64_RS08615	COG0006	proline dipeptidase activity
EGM64_RS08645	COG2205	protein histidine kinase activity
EGM64_RS08650	COG0745	RESPONSE REGULATOR receiver
EGM64_RS08665	COG2188	Transcriptional regulator
EGM64_RS08690	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EGM64_RS08695	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EGM64_RS08705	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EGM64_RS08725	COG0505	Belongs to the CarA family
EGM64_RS08735	COG0284	orotidine-5'-phosphate decarboxylase activity
EGM64_RS08750	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
EGM64_RS08755	COG1758	RNA polymerase activity
EGM64_RS08765	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EGM64_RS08770	COG2072	flavoprotein involved in K transport
EGM64_RS08775	COG0657	acetylesterase activity
EGM64_RS08800	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EGM64_RS08835	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EGM64_RS08835	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EGM64_RS08840	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EGM64_RS08865	COG0322	excinuclease ABC activity
EGM64_RS08870	COG1660	Displays ATPase and GTPase activities
EGM64_RS08885	COG3328	transposase activity
EGM64_RS08925	COG0657	acetylesterase activity
EGM64_RS08930	COG0318	PFAM AMP-dependent synthetase and ligase
EGM64_RS08965	COG0149	triose-phosphate isomerase activity
EGM64_RS08980	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
EGM64_RS08990	COG0667	Aldo Keto reductase
EGM64_RS08995	COG0123	including yeast histone deacetylase and acetoin utilization protein
EGM64_RS09020	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EGM64_RS09030	COG0109	protoheme IX farnesyltransferase activity
EGM64_RS09080	COG0396	ATPase activity
EGM64_RS09095	COG2151	metal-sulfur cluster biosynthetic enzyme
EGM64_RS09115	COG1960	acyl-CoA dehydrogenase activity
EGM64_RS09120	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EGM64_RS09130	COG0488	(ABC) transporter
EGM64_RS09140	COG1309	transcriptional regulator
EGM64_RS09155	COG0791	NLP P60 protein
EGM64_RS09155	COG3883	PFAM NLP P60 protein
EGM64_RS09165	COG0714	Associated with various cellular activities
EGM64_RS09175	COG2304	oxidoreductase activity
EGM64_RS09195	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EGM64_RS09245	COG0745	RESPONSE REGULATOR receiver
EGM64_RS09250	COG5002	protein histidine kinase activity
EGM64_RS09285	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EGM64_RS09305	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
EGM64_RS09310	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EGM64_RS09375	COG2070	2-Nitropropane dioxygenase
EGM64_RS09390	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EGM64_RS09405	COG0252	asparaginase activity
EGM64_RS09425	COG2346	COG2346, Truncated hemoglobins
EGM64_RS09435	COG0300	oxidoreductase activity
EGM64_RS09520	COG0791	NLP P60 protein
EGM64_RS09520	COG3883	PFAM NLP P60 protein
EGM64_RS09530	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EGM64_RS09535	COG0156	8-amino-7-oxononanoate synthase activity
EGM64_RS09555	COG5002	protein histidine kinase activity
EGM64_RS09580	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EGM64_RS09600	COG3547	Transposase (IS116 IS110 IS902 family)
EGM64_RS09610	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EGM64_RS09615	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EGM64_RS09620	COG0157	Belongs to the NadC ModD family
EGM64_RS09630	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EGM64_RS09635	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EGM64_RS09645	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EGM64_RS09650	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EGM64_RS09655	COG0483	inositol monophosphate 1-phosphatase activity
EGM64_RS09660	COG0107	imidazoleglycerol-phosphate synthase activity
EGM64_RS09665	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EGM64_RS09670	COG0387	Pfam Sodium calcium exchanger
EGM64_RS09700	COG0159	tryptophan synthase activity
EGM64_RS09720	COG1946	Acyl-CoA thioesterase
EGM64_RS09730	COG1132	(ABC) transporter
EGM64_RS09735	COG4988	ABC transporter
EGM64_RS09740	COG1294	oxidase, subunit
EGM64_RS09745	COG1271	oxidase subunit
EGM64_RS09775	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EGM64_RS09795	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
EGM64_RS09805	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EGM64_RS09805	COG0237	dephospho-CoA kinase activity
EGM64_RS09815	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EGM64_RS09830	COG0842	Transport permease protein
EGM64_RS09830	COG1716	ATPase activity
EGM64_RS09830	COG1131	(ABC) transporter
EGM64_RS09865	COG1285	pathogenesis
EGM64_RS09925	COG1309	transcriptional regulator
EGM64_RS09940	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EGM64_RS09940	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EGM64_RS09980	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EGM64_RS09985	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EGM64_RS09985	COG0072	phenylalanine-tRNA ligase activity
EGM64_RS09990	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EGM64_RS09995	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EGM64_RS10000	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EGM64_RS10010	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EGM64_RS10015	COG1438	arginine binding
EGM64_RS10020	COG0137	argininosuccinate synthase activity
EGM64_RS10025	COG0165	Argininosuccinate lyase
EGM64_RS10065	COG0488	(ABC) transporter
EGM64_RS10075	COG0583	DNA-binding transcription factor activity
EGM64_RS10095	COG1028	Short-chain dehydrogenase reductase Sdr
EGM64_RS10100	COG1028	Short-chain dehydrogenase reductase Sdr
EGM64_RS10105	COG4948	Mandelate Racemase Muconate Lactonizing
EGM64_RS10110	COG0300	oxidoreductase activity
EGM64_RS10145	COG2835	tetraacyldisaccharide 4'-kinase activity
EGM64_RS10150	COG1309	transcriptional regulator
EGM64_RS10160	COG1131	(ABC) transporter
EGM64_RS10170	COG2094	Belongs to the DNA glycosylase MPG family
EGM64_RS10175	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EGM64_RS10190	COG0647	UMP catabolic process
EGM64_RS10205	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EGM64_RS10230	COG0494	nUDIX hydrolase
EGM64_RS10255	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EGM64_RS10265	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EGM64_RS10270	COG1160	GTP binding
EGM64_RS10310	COG0189	ligase activity
EGM64_RS10310	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EGM64_RS10315	COG2271	Major facilitator Superfamily
EGM64_RS10335	COG2132	Multicopper oxidase
EGM64_RS10360	COG1403	HNH endonuclease
EGM64_RS10365	COG1053	succinate dehydrogenase
EGM64_RS10380	COG1028	Short-chain dehydrogenase reductase Sdr
EGM64_RS10385	COG1028	Short-chain dehydrogenase reductase Sdr
EGM64_RS10395	COG0657	acetylesterase activity
EGM64_RS10410	COG2072	flavoprotein involved in K transport
EGM64_RS10415	COG1028	Short-chain dehydrogenase reductase Sdr
EGM64_RS10430	COG0657	acetylesterase activity
EGM64_RS10460	COG2072	flavoprotein involved in K transport
EGM64_RS10470	COG2267	carboxylic ester hydrolase activity
EGM64_RS10490	COG1028	Short-chain dehydrogenase reductase Sdr
EGM64_RS10495	COG0657	acetylesterase activity
EGM64_RS10500	COG1131	(ABC) transporter
EGM64_RS10500	COG1716	ATPase activity
EGM64_RS10500	COG0842	Transport permease protein
EGM64_RS10505	COG1960	acyl-CoA dehydrogenase activity
EGM64_RS10510	COG1960	acyl-CoA dehydrogenase activity
EGM64_RS10535	COG2072	flavoprotein involved in K transport
EGM64_RS10540	COG0318	PFAM AMP-dependent synthetase and ligase
EGM64_RS10560	COG4221	oxidoreductase activity
EGM64_RS10620	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EGM64_RS10625	COG0513	Belongs to the DEAD box helicase family
EGM64_RS10635	COG1053	succinate dehydrogenase
EGM64_RS10650	COG1024	Enoyl-CoA hydratase
EGM64_RS10660	COG0022	dehydrogenase e1 component
EGM64_RS10665	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EGM64_RS10670	COG1028	Short-chain dehydrogenase reductase Sdr
EGM64_RS10705	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EGM64_RS10745	COG5651	PPE family
EGM64_RS10755	COG5651	PPE family
EGM64_RS10785	COG1404	Belongs to the peptidase S8 family
EGM64_RS10800	COG0657	acetylesterase activity
EGM64_RS10845	COG5651	PPE family
EGM64_RS10855	COG1285	pathogenesis
EGM64_RS10885	COG1053	succinate dehydrogenase
EGM64_RS10900	COG0653	protein targeting
EGM64_RS10950	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EGM64_RS10950	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EGM64_RS10970	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EGM64_RS10975	COG1253	flavin adenine dinucleotide binding
EGM64_RS10980	COG1253	flavin adenine dinucleotide binding
EGM64_RS10990	COG1960	acyl-CoA dehydrogenase activity
EGM64_RS10995	COG0318	PFAM AMP-dependent synthetase and ligase
EGM64_RS11000	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EGM64_RS11010	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EGM64_RS11030	COG1252	NADH dehydrogenase
EGM64_RS11040	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGM64_RS11090	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
EGM64_RS11095	COG4221	oxidoreductase activity
EGM64_RS11100	COG1968	undecaprenyl-diphosphatase activity
EGM64_RS11105	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EGM64_RS11110	COG0183	Belongs to the thiolase family
EGM64_RS11165	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EGM64_RS11190	COG1024	Enoyl-CoA hydratase
EGM64_RS11200	COG2193	ferroxidase activity
EGM64_RS11210	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EGM64_RS11220	COG0174	glutamine synthetase
EGM64_RS11260	COG1652	LysM domain
EGM64_RS11315	COG2070	2-Nitropropane dioxygenase
EGM64_RS11320	COG1403	HNH endonuclease
EGM64_RS11330	COG1063	alcohol dehydrogenase
EGM64_RS11335	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EGM64_RS11340	COG1490	D-aminoacyl-tRNA deacylase activity
EGM64_RS11350	COG1546	Belongs to the CinA family
EGM64_RS11350	COG1058	Belongs to the CinA family
EGM64_RS11355	COG2814	Major facilitator Superfamily
EGM64_RS11365	COG1950	PFAM Membrane protein of
EGM64_RS11425	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
EGM64_RS11445	COG0640	Transcriptional regulator
EGM64_RS11500	COG4977	sequence-specific DNA binding
EGM64_RS11530	COG1012	belongs to the aldehyde dehydrogenase family
EGM64_RS11545	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EGM64_RS11575	COG2226	methyltransferase
EGM64_RS11580	COG0438	transferase activity, transferring glycosyl groups
EGM64_RS11585	COG3757	hydrolase, family 25
EGM64_RS11590	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
EGM64_RS11600	COG1376	ErfK ybiS ycfS ynhG family protein
EGM64_RS11610	COG0723	plastoquinol--plastocyanin reductase activity
EGM64_RS11655	COG1024	Enoyl-CoA hydratase
EGM64_RS11670	COG1643	Atp-dependent helicase
EGM64_RS11675	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EGM64_RS11700	COG2301	Belongs to the HpcH HpaI aldolase family
EGM64_RS11720	COG1028	Short-chain dehydrogenase reductase Sdr
EGM64_RS11725	COG0545	Peptidyl-prolyl cis-trans isomerase
EGM64_RS11735	COG0484	heat shock protein binding
EGM64_RS11745	COG0789	Transcriptional regulator
EGM64_RS11755	COG0301	tRNA thio-modification
EGM64_RS11800	COG1028	Short-chain dehydrogenase reductase Sdr
EGM64_RS11815	COG2267	carboxylic ester hydrolase activity
EGM64_RS11820	COG1309	transcriptional regulator
EGM64_RS11830	COG1960	acyl-CoA dehydrogenase activity
EGM64_RS11835	COG0183	Belongs to the thiolase family
EGM64_RS11845	COG1028	Short-chain dehydrogenase reductase Sdr
EGM64_RS11910	COG0753	catalase activity
EGM64_RS11940	COG1946	Acyl-CoA thioesterase
EGM64_RS11970	COG0657	acetylesterase activity
EGM64_RS12035	COG1960	acyl-CoA dehydrogenase activity
EGM64_RS12050	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EGM64_RS12055	COG0667	Aldo Keto reductase
EGM64_RS12095	COG2837	iron assimilation
EGM64_RS12120	COG1752	Esterase of the alpha-beta hydrolase superfamily
EGM64_RS12125	COG3842	ATPase activity
EGM64_RS12130	COG0395	ABC-type sugar transport system, permease component
EGM64_RS12135	COG1175	transmembrane transport
EGM64_RS12145	COG1595	DNA-templated transcription, initiation
EGM64_RS12170	COG1335	isochorismatase
EGM64_RS12190	COG3265	gluconokinase activity
EGM64_RS12200	COG2272	Belongs to the type-B carboxylesterase lipase family
EGM64_RS12260	COG0714	Associated with various cellular activities
EGM64_RS12290	COG3321	synthase
EGM64_RS12290	COG0604	alcohol dehydrogenase
EGM64_RS12315	COG1574	metal-dependent hydrolase with the TIM-barrel fold
EGM64_RS12325	COG0412	Dienelactone hydrolase
EGM64_RS12355	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EGM64_RS12435	COG2826	transposase and inactivated derivatives, IS30 family
EGM64_RS12465	COG2378	regulation of single-species biofilm formation
EGM64_RS12485	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
EGM64_RS12545	COG0140	phosphoribosyl-ATP diphosphatase activity
EGM64_RS12560	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EGM64_RS12605	COG0646	methionine synthase
EGM64_RS12605	COG1410	methionine synthase
EGM64_RS12615	COG1028	Short-chain dehydrogenase reductase Sdr
EGM64_RS12650	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EGM64_RS12660	COG0028	Belongs to the TPP enzyme family
EGM64_RS12675	COG0215	cysteine-tRNA ligase activity
EGM64_RS12685	COG1218	3'(2'),5'-bisphosphate nucleotidase
EGM64_RS12720	COG0167	dihydroorotate dehydrogenase activity
EGM64_RS12725	COG1403	HNH endonuclease
EGM64_RS12735	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EGM64_RS12770	COG1799	cell septum assembly
EGM64_RS12785	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EGM64_RS12795	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EGM64_RS12800	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EGM64_RS12810	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EGM64_RS12825	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EGM64_RS12830	COG0768	penicillin binding
EGM64_RS12840	COG0275	rRNA processing
EGM64_RS12870	COG0142	geranyltranstransferase activity
EGM64_RS12890	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EGM64_RS12895	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
EGM64_RS12925	COG0003	Pfam Anion-transporting ATPase
EGM64_RS12940	COG1022	Amp-dependent synthetase and ligase
EGM64_RS12970	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EGM64_RS12975	COG1845	cytochrome c oxidase, subunit III
EGM64_RS13015	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EGM64_RS13030	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EGM64_RS13060	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
EGM64_RS13065	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
EGM64_RS13070	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EGM64_RS13075	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EGM64_RS13085	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EGM64_RS13115	COG0321	lipoyl(octanoyl) transferase activity
EGM64_RS13120	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EGM64_RS13150	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
EGM64_RS13175	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EGM64_RS13265	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
EGM64_RS13275	COG0596	Alpha beta hydrolase
EGM64_RS13320	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EGM64_RS13340	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EGM64_RS13370	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EGM64_RS13430	COG2072	flavoprotein involved in K transport
EGM64_RS13445	COG0860	N-Acetylmuramoyl-L-alanine amidase
EGM64_RS13475	COG1487	ribonuclease activity
EGM64_RS13520	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EGM64_RS13540	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EGM64_RS13550	COG0657	acetylesterase activity
EGM64_RS13565	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EGM64_RS13570	COG0438	transferase activity, transferring glycosyl groups
EGM64_RS13595	COG3547	Transposase (IS116 IS110 IS902 family)
EGM64_RS13600	COG2124	cytochrome p450
EGM64_RS13615	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGM64_RS13620	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EGM64_RS13630	COG0596	Alpha beta hydrolase
EGM64_RS13655	COG0697	spore germination
EGM64_RS13670	COG2239	Acts as a magnesium transporter
EGM64_RS13690	COG0326	Molecular chaperone. Has ATPase activity
EGM64_RS13720	COG2226	methyltransferase
EGM64_RS13725	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EGM64_RS13745	COG3629	intracellular signal transduction
EGM64_RS13745	COG3903	Transcriptional regulator
EGM64_RS13755	COG2814	Major facilitator Superfamily
EGM64_RS13760	COG0563	adenylate kinase activity
EGM64_RS13770	COG1012	belongs to the aldehyde dehydrogenase family
EGM64_RS13815	COG1175	transmembrane transport
EGM64_RS13820	COG0395	ABC-type sugar transport system, permease component
EGM64_RS13830	COG0531	amino acid
EGM64_RS13835	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EGM64_RS13840	COG1834	amidinotransferase
EGM64_RS13845	COG1522	sequence-specific DNA binding
EGM64_RS13865	COG1716	ATPase activity
EGM64_RS13865	COG1131	(ABC) transporter
EGM64_RS13865	COG0842	Transport permease protein
EGM64_RS13875	COG2223	nitrite transmembrane transporter activity
EGM64_RS13885	COG0243	molybdopterin cofactor binding
EGM64_RS13890	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EGM64_RS13930	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EGM64_RS13960	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EGM64_RS13965	COG4424	Sulfotransferase
EGM64_RS13970	COG2855	membrane
EGM64_RS13975	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EGM64_RS13995	COG1045	serine acetyltransferase
EGM64_RS14005	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGM64_RS14010	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGM64_RS14060	COG0423	glycine-tRNA ligase activity
EGM64_RS14085	COG1381	Involved in DNA repair and RecF pathway recombination
EGM64_RS14095	COG1982	Orn Lys Arg decarboxylase major
EGM64_RS14100	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EGM64_RS14130	COG3328	transposase activity
EGM64_RS14200	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EGM64_RS14215	COG0484	heat shock protein binding
EGM64_RS14220	COG1420	regulation of RNA biosynthetic process
EGM64_RS14235	COG1595	DNA-templated transcription, initiation
EGM64_RS14255	COG3486	L-lysine 6-monooxygenase (NADPH) activity
EGM64_RS14270	COG3321	synthase
EGM64_RS14270	COG0604	alcohol dehydrogenase
EGM64_RS14285	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EGM64_RS14305	COG1309	transcriptional regulator
EGM64_RS14360	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EGM64_RS14385	COG0657	acetylesterase activity
EGM64_RS14390	COG0300	oxidoreductase activity
EGM64_RS14400	COG2072	flavoprotein involved in K transport
EGM64_RS14430	COG1169	isochorismate synthase
EGM64_RS14450	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EGM64_RS14460	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EGM64_RS14465	COG4208	sulfate ABC transporter
EGM64_RS14470	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EGM64_RS14475	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EGM64_RS14490	COG3387	PFAM Glycoside hydrolase 15-related
EGM64_RS14500	COG0481	GTPase activity
EGM64_RS14520	COG1305	Transglutaminase-like
EGM64_RS14530	COG2308	Evidence 4 Homologs of previously reported genes of
EGM64_RS14545	COG0658	competence protein
EGM64_RS14545	COG2333	competence protein COMEC
EGM64_RS14550	COG1596	polysaccharide export
EGM64_RS14550	COG1555	photosystem II stabilization
EGM64_RS14555	COG1960	acyl-CoA dehydrogenase activity
EGM64_RS14560	COG1960	acyl-CoA dehydrogenase activity
EGM64_RS14585	COG5651	PPE family
EGM64_RS14590	COG0318	PFAM AMP-dependent synthetase and ligase
EGM64_RS14620	COG2755	lipolytic protein G-D-S-L family
EGM64_RS14630	COG0799	negative regulation of ribosome biogenesis
EGM64_RS14635	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EGM64_RS14645	COG0542	response to heat
EGM64_RS14650	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EGM64_RS14660	COG5002	protein histidine kinase activity
EGM64_RS14665	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EGM64_RS14670	COG2188	Transcriptional regulator
EGM64_RS14685	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EGM64_RS14690	COG0066	3-isopropylmalate dehydratase activity
EGM64_RS14725	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EGM64_RS14730	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EGM64_RS14745	COG1530	ribonuclease E activity
EGM64_RS14750	COG0105	UTP biosynthetic process
EGM64_RS14760	COG0285	dihydrofolate synthase activity
EGM64_RS14765	COG0525	valine-tRNA ligase activity
EGM64_RS14770	COG3268	Saccharopine dehydrogenase
EGM64_RS14775	COG1388	LysM domain
EGM64_RS14780	COG3328	transposase activity
EGM64_RS14785	COG0746	molybdenum cofactor guanylyltransferase activity
EGM64_RS14790	COG1013	pyruvate-flavodoxin oxidoreductase activity
EGM64_RS14795	COG0674	pyruvate-flavodoxin oxidoreductase activity
EGM64_RS14795	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EGM64_RS14805	COG2040	homocysteine
EGM64_RS14810	COG0740	serine-type endopeptidase activity
EGM64_RS14815	COG0740	serine-type endopeptidase activity
EGM64_RS14835	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EGM64_RS14850	COG0698	ribose 5-phosphate isomerase
EGM64_RS14855	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EGM64_RS14880	COG2346	COG2346, Truncated hemoglobins
EGM64_RS14905	COG2902	Dehydrogenase
EGM64_RS14915	COG0629	single-stranded DNA binding
EGM64_RS14925	COG2937	Belongs to the GPAT DAPAT family
EGM64_RS14940	COG0657	acetylesterase activity
EGM64_RS14950	COG2801	Transposase and inactivated derivatives
EGM64_RS14950	COG3415	Transposase
EGM64_RS14980	COG0508	dehydrogenase complex catalyzes the overall conversion of
EGM64_RS15000	COG2030	dehydratase
EGM64_RS15005	COG1960	acyl-CoA dehydrogenase activity
EGM64_RS15015	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EGM64_RS15035	COG0300	oxidoreductase activity
EGM64_RS15040	COG0433	COG0433 Predicted ATPase
EGM64_RS15045	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
EGM64_RS15060	COG1376	ErfK ybiS ycfS ynhG family protein
EGM64_RS15070	COG2409	Drug exporters of the RND superfamily
EGM64_RS15075	COG4552	Acetyltransferase involved in intracellular survival and related
EGM64_RS15105	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EGM64_RS15110	COG0736	holo-[acyl-carrier-protein] synthase activity
EGM64_RS15125	COG3757	hydrolase, family 25
EGM64_RS15175	COG2124	cytochrome p450
EGM64_RS15205	COG1960	acyl-CoA dehydrogenase activity
EGM64_RS15210	COG1960	acyl-CoA dehydrogenase activity
EGM64_RS15215	COG1960	acyl-CoA dehydrogenase activity
EGM64_RS15220	COG1960	acyl-CoA dehydrogenase activity
EGM64_RS15250	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EGM64_RS15265	COG1960	acyl-CoA dehydrogenase activity
EGM64_RS15270	COG1960	acyl-CoA dehydrogenase activity
EGM64_RS15275	COG0657	acetylesterase activity
EGM64_RS15280	COG2124	cytochrome p450
EGM64_RS15300	COG1309	transcriptional regulator
EGM64_RS15315	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EGM64_RS15335	COG2072	flavoprotein involved in K transport
EGM64_RS15340	COG4638	Rieske (2fe-2S)
EGM64_RS15365	COG2124	cytochrome p450
EGM64_RS15375	COG0183	Belongs to the thiolase family
EGM64_RS15380	COG1960	acyl-CoA dehydrogenase activity
EGM64_RS15405	COG1024	Enoyl-CoA hydratase
EGM64_RS15420	COG1028	Short-chain dehydrogenase reductase Sdr
EGM64_RS15440	COG1024	Enoyl-CoA hydratase
EGM64_RS15445	COG1024	Enoyl-CoA hydratase
EGM64_RS15450	COG1024	Enoyl-CoA hydratase
EGM64_RS15465	COG0318	PFAM AMP-dependent synthetase and ligase
EGM64_RS15475	COG1802	Transcriptional regulator
EGM64_RS15480	COG1960	acyl-CoA dehydrogenase activity
EGM64_RS15485	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EGM64_RS15490	COG0183	Belongs to the thiolase family
EGM64_RS15500	COG1960	acyl-CoA dehydrogenase activity
EGM64_RS15505	COG1028	Short-chain dehydrogenase reductase Sdr
EGM64_RS15565	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EGM64_RS15570	COG2123	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EGM64_RS15575	COG1234	tRNA 3'-trailer cleavage
EGM64_RS15580	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EGM64_RS15590	COG3191	aminopeptidase activity
EGM64_RS15605	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EGM64_RS15615	COG0058	SHG alpha-glucan phosphorylase activity
EGM64_RS15625	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EGM64_RS15640	COG0346	lactoylglutathione lyase activity
EGM64_RS15665	COG2814	Major facilitator Superfamily
EGM64_RS15670	COG0583	DNA-binding transcription factor activity
EGM64_RS15690	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EGM64_RS15715	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EGM64_RS15735	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EGM64_RS15750	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EGM64_RS15750	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EGM64_RS15760	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EGM64_RS15765	COG0356	it plays a direct role in the translocation of protons across the membrane
EGM64_RS15785	COG2890	protein-(glutamine-N5) methyltransferase activity
EGM64_RS15790	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EGM64_RS15810	COG0083	homoserine kinase activity
EGM64_RS15820	COG0460	homoserine dehydrogenase
EGM64_RS15830	COG0018	arginyl-trna synthetase
EGM64_RS15875	COG0494	nUDIX hydrolase
EGM64_RS15880	COG3631	Ketosteroid isomerase-related protein
EGM64_RS15970	COG1403	HNH endonuclease
EGM64_RS16050	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGM64_RS16070	COG0277	FAD linked oxidase domain protein
EGM64_RS16120	COG1028	Short-chain dehydrogenase reductase Sdr
EGM64_RS16130	COG1028	Short-chain dehydrogenase reductase Sdr
EGM64_RS16140	COG1028	Short-chain dehydrogenase reductase Sdr
EGM64_RS16170	COG0508	dehydrogenase complex catalyzes the overall conversion of
EGM64_RS16170	COG0567	Dehydrogenase, E1 component
EGM64_RS16195	COG0039	L-malate dehydrogenase activity
EGM64_RS16200	COG0598	Magnesium transport protein CorA
EGM64_RS16245	COG2239	Acts as a magnesium transporter
EGM64_RS16265	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EGM64_RS16270	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EGM64_RS16275	COG5662	AntiSigma factor
EGM64_RS16285	COG4122	O-methyltransferase activity
EGM64_RS16295	COG1131	(ABC) transporter
EGM64_RS16300	COG3559	Exporter of polyketide antibiotics
EGM64_RS16315	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EGM64_RS16335	COG0519	Catalyzes the synthesis of GMP from XMP
EGM64_RS16345	COG0463	Glycosyl transferase, family 2
EGM64_RS16355	COG0318	PFAM AMP-dependent synthetase and ligase
EGM64_RS16360	COG1611	Belongs to the LOG family
EGM64_RS16400	COG0477	Major facilitator Superfamily
EGM64_RS16405	COG0318	PFAM AMP-dependent synthetase and ligase
EGM64_RS16415	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EGM64_RS16425	COG2124	cytochrome p450
EGM64_RS16430	COG1960	acyl-CoA dehydrogenase activity
EGM64_RS16445	COG1960	acyl-CoA dehydrogenase activity
EGM64_RS16465	COG0506	proline dehydrogenase activity
EGM64_RS16470	COG1012	belongs to the aldehyde dehydrogenase family
EGM64_RS16485	COG0318	PFAM AMP-dependent synthetase and ligase
EGM64_RS16495	COG2046	Belongs to the sulfate adenylyltransferase family
EGM64_RS16500	COG0529	Catalyzes the synthesis of activated sulfate
EGM64_RS16535	COG0531	amino acid
EGM64_RS16545	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EGM64_RS16550	COG2801	Transposase and inactivated derivatives
EGM64_RS16550	COG3415	Transposase
EGM64_RS16565	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
EGM64_RS16575	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EGM64_RS16590	COG1217	gtp-binding protein TYPA
EGM64_RS16605	COG1140	nitrate reductase beta subunit
EGM64_RS16625	COG2154	pterin-4-alpha-carbinolamine dehydratase
EGM64_RS16660	COG3467	pyridoxamine 5'-phosphate
EGM64_RS16675	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EGM64_RS16685	COG2409	Drug exporters of the RND superfamily
EGM64_RS16705	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EGM64_RS16710	COG1024	Enoyl-CoA hydratase
EGM64_RS16720	COG0702	epimerase
EGM64_RS16740	COG1024	Enoyl-CoA hydratase
EGM64_RS16745	COG0183	Belongs to the thiolase family
EGM64_RS16755	COG2124	cytochrome p450
EGM64_RS16760	COG1028	Short-chain dehydrogenase reductase Sdr
EGM64_RS16775	COG0714	Associated with various cellular activities
EGM64_RS16785	COG1960	acyl-CoA dehydrogenase activity
EGM64_RS16790	COG1960	acyl-CoA dehydrogenase activity
EGM64_RS16800	COG1309	transcriptional regulator
EGM64_RS16815	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EGM64_RS16830	COG0574	Belongs to the PEP-utilizing enzyme family
EGM64_RS16830	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EGM64_RS16860	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EGM64_RS16935	COG0012	GTP binding
EGM64_RS16945	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EGM64_RS16955	COG1570	exodeoxyribonuclease VII activity
EGM64_RS16970	COG2272	Belongs to the type-B carboxylesterase lipase family
EGM64_RS17010	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EGM64_RS17020	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EGM64_RS17025	COG0572	uridine kinase
EGM64_RS17055	COG1331	Highly conserved protein containing a thioredoxin domain
EGM64_RS17065	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EGM64_RS17070	COG1946	Acyl-CoA thioesterase
EGM64_RS17105	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EGM64_RS17110	COG0025	NhaP-type Na H and K H
EGM64_RS17125	COG0667	Aldo Keto reductase
EGM64_RS17130	COG4762	Protein conserved in bacteria
EGM64_RS17175	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EGM64_RS17180	COG3485	protocatechuate 3,4-dioxygenase
EGM64_RS17185	COG3485	protocatechuate 3,4-dioxygenase
EGM64_RS17225	COG1414	Transcriptional regulator
EGM64_RS17245	COG1366	Belongs to the anti-sigma-factor antagonist family
EGM64_RS17255	COG0753	catalase activity
EGM64_RS17260	COG1028	Short-chain dehydrogenase reductase Sdr
EGM64_RS17275	COG1024	Enoyl-CoA hydratase
EGM64_RS17315	COG4974	Belongs to the 'phage' integrase family
EGM64_RS17500	COG1309	transcriptional regulator
EGM64_RS17510	COG1028	Short-chain dehydrogenase reductase Sdr
EGM64_RS17520	COG1012	belongs to the aldehyde dehydrogenase family
EGM64_RS17590	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EGM64_RS17615	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EGM64_RS17635	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EGM64_RS17645	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EGM64_RS17650	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EGM64_RS17655	COG0531	amino acid
EGM64_RS17660	COG0569	domain protein
EGM64_RS17710	COG0483	inositol monophosphate 1-phosphatase activity
EGM64_RS17795	COG4044	May play a role in the intracellular transport of hydrophobic ligands
EGM64_RS17805	COG1388	LysM domain
EGM64_RS17810	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EGM64_RS17825	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EGM64_RS17830	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EGM64_RS17835	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EGM64_RS17850	COG1196	nuclear chromosome segregation
EGM64_RS17860	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EGM64_RS17895	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
EGM64_RS17910	COG1842	Phage shock protein A
EGM64_RS17925	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EGM64_RS17930	COG1674	ftsk spoiiie
EGM64_RS17955	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EGM64_RS17970	COG3214	Protein conserved in bacteria
EGM64_RS17985	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EGM64_RS18000	COG1028	Short-chain dehydrogenase reductase Sdr
EGM64_RS18010	COG4770	biotin carboxylase activity
EGM64_RS18015	COG0318	PFAM AMP-dependent synthetase and ligase
EGM64_RS18035	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EGM64_RS18045	COG1403	HNH endonuclease
EGM64_RS18090	COG0686	Belongs to the AlaDH PNT family
EGM64_RS18105	COG1185	polyribonucleotide nucleotidyltransferase activity
EGM64_RS18125	COG1960	acyl-CoA dehydrogenase activity
EGM64_RS18130	COG0183	Belongs to the thiolase family
EGM64_RS18135	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EGM64_RS18140	COG2977	Belongs to the P-Pant transferase superfamily
EGM64_RS18145	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EGM64_RS18170	COG1024	Enoyl-CoA hydratase
EGM64_RS18180	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EGM64_RS18190	COG0481	GTPase activity
EGM64_RS18205	COG0779	Required for maturation of 30S ribosomal subunits
EGM64_RS18220	COG0442	prolyl-tRNA aminoacylation
EGM64_RS18235	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EGM64_RS18235	COG1648	precorrin-2 dehydrogenase activity
EGM64_RS18265	COG0579	oxidoreductase
EGM64_RS18280	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
EGM64_RS18300	COG1028	Short-chain dehydrogenase reductase Sdr
EGM64_RS18305	COG1012	belongs to the aldehyde dehydrogenase family
EGM64_RS18310	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EGM64_RS18325	COG1492	cobalamin metabolic process
EGM64_RS18350	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EGM64_RS18355	COG0750	zinc metalloprotease
EGM64_RS18360	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EGM64_RS18380	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EGM64_RS18385	COG0575	Belongs to the CDS family
EGM64_RS18395	COG0528	UMP kinase activity
EGM64_RS18405	COG0745	RESPONSE REGULATOR receiver
EGM64_RS18420	COG1028	Short-chain dehydrogenase reductase Sdr
EGM64_RS18435	COG0154	amidase activity
EGM64_RS18440	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EGM64_RS18445	COG0052	Belongs to the universal ribosomal protein uS2 family
EGM64_RS18505	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EGM64_RS18515	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EGM64_RS18535	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EGM64_RS18555	COG0336	Belongs to the RNA methyltransferase TrmD family
EGM64_RS18560	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EGM64_RS18580	COG1686	Belongs to the peptidase S11 family
EGM64_RS18615	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
EGM64_RS18635	COG1196	nuclear chromosome segregation
EGM64_RS18650	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EGM64_RS18655	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EGM64_RS18660	COG0571	ribonuclease III activity
EGM64_RS18680	COG0701	Predicted permease
EGM64_RS18685	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EGM64_RS18700	COG0742	ribosomal rna small subunit methyltransferase
EGM64_RS18715	COG0657	acetylesterase activity
EGM64_RS18725	COG0656	L-ascorbic acid biosynthetic process
EGM64_RS18740	COG1461	Dihydroxyacetone kinase
EGM64_RS18780	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EGM64_RS18795	COG1181	Belongs to the D-alanine--D-alanine ligase family
EGM64_RS18800	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EGM64_RS18805	COG1920	GTP binding
EGM64_RS18810	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EGM64_RS18825	COG0066	3-isopropylmalate dehydratase activity
EGM64_RS18830	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EGM64_RS18855	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EGM64_RS18860	COG0179	Fumarylacetoacetate (FAA) hydrolase
EGM64_RS18865	COG2271	Major facilitator Superfamily
EGM64_RS18870	COG0473	3-isopropylmalate dehydrogenase activity
EGM64_RS18885	COG0655	NAD(P)H dehydrogenase (quinone) activity
EGM64_RS18910	COG2259	Doxx family
EGM64_RS18925	COG1192	Involved in chromosome partitioning
EGM64_RS18930	COG0205	6-phosphofructokinase activity
EGM64_RS18935	COG0154	amidase activity
EGM64_RS18975	COG0626	cystathionine gamma-synthase activity
EGM64_RS18995	COG0482	sulfurtransferase activity
EGM64_RS19060	COG0142	geranyltranstransferase activity
EGM64_RS19110	COG3415	Transposase
EGM64_RS19110	COG2801	Transposase and inactivated derivatives
EGM64_RS19115	COG1304	FMN binding
EGM64_RS19120	COG2409	Drug exporters of the RND superfamily
EGM64_RS19130	COG0415	Belongs to the DNA photolyase family
EGM64_RS19140	COG0110	maltose O-acetyltransferase activity
EGM64_RS19145	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EGM64_RS19170	COG1024	Enoyl-CoA hydratase
EGM64_RS19180	COG1119	ATPase activity
EGM64_RS19190	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EGM64_RS19210	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EGM64_RS19215	COG2226	methyltransferase
EGM64_RS19215	COG2867	negative regulation of translational initiation
EGM64_RS19220	COG1309	transcriptional regulator
EGM64_RS19225	COG2072	flavoprotein involved in K transport
EGM64_RS19230	COG1309	transcriptional regulator
EGM64_RS19300	COG2186	Transcriptional regulator
EGM64_RS19315	COG1960	acyl-CoA dehydrogenase activity
EGM64_RS19325	COG1793	dna ligase
EGM64_RS19330	COG1966	Carbon starvation protein
EGM64_RS19335	COG0443	Heat shock 70 kDa protein
EGM64_RS19340	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGM64_RS19345	COG1024	Enoyl-CoA hydratase
EGM64_RS19370	COG1028	Short-chain dehydrogenase reductase Sdr
EGM64_RS19380	COG2076	Multidrug Resistance protein
EGM64_RS19415	COG0148	phosphopyruvate hydratase activity
EGM64_RS19425	COG2175	clavaminate synthase activity
EGM64_RS19435	COG4638	Rieske (2fe-2S)
EGM64_RS19440	COG1028	Short-chain dehydrogenase reductase Sdr
EGM64_RS19465	COG4638	Rieske (2fe-2S)
EGM64_RS19485	COG3654	unkown
EGM64_RS19500	COG0477	Major facilitator Superfamily
EGM64_RS19510	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EGM64_RS19515	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EGM64_RS19535	COG2301	Belongs to the HpcH HpaI aldolase family
EGM64_RS19545	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EGM64_RS19575	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EGM64_RS19600	COG1819	glycosyl
EGM64_RS19635	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EGM64_RS19640	COG2177	Part of the ABC transporter FtsEX involved in
EGM64_RS19645	COG2884	Cell division ATP-binding protein ftsE
EGM64_RS19655	COG0668	transmembrane transport
EGM64_RS19665	COG0493	'glutamate synthase
EGM64_RS19715	COG0483	inositol monophosphate 1-phosphatase activity
EGM64_RS19725	COG1960	acyl-CoA dehydrogenase activity
EGM64_RS19745	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EGM64_RS19750	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EGM64_RS19760	COG1960	acyl-CoA dehydrogenase activity
EGM64_RS19800	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EGM64_RS19820	COG1034	ATP synthesis coupled electron transport
EGM64_RS19825	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EGM64_RS19860	COG1309	transcriptional regulator
EGM64_RS19865	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EGM64_RS19880	COG0714	Associated with various cellular activities
EGM64_RS19930	COG0477	Major facilitator Superfamily
EGM64_RS19955	COG2201	protein-glutamate methylesterase activity
EGM64_RS19970	COG2201	protein-glutamate methylesterase activity
EGM64_RS19995	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EGM64_RS20035	COG0297	glycogen (starch) synthase activity
EGM64_RS20045	COG1088	dTDP-glucose 4,6-dehydratase activity
EGM64_RS20050	COG2192	nodulation
EGM64_RS20055	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EGM64_RS20065	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
EGM64_RS20070	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
EGM64_RS20070	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EGM64_RS20075	COG1028	Short-chain dehydrogenase reductase Sdr
EGM64_RS20085	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EGM64_RS20090	COG0028	Belongs to the TPP enzyme family
EGM64_RS20095	COG1573	uracil-dna glycosylase
EGM64_RS20155	COG0789	Transcriptional regulator
EGM64_RS20165	COG3707	response regulator
EGM64_RS20190	COG4585	Histidine kinase
EGM64_RS20195	COG2197	response regulator
EGM64_RS20285	COG3480	Lon protease (S16) C-terminal proteolytic domain
EGM64_RS20300	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EGM64_RS20330	COG0210	DNA helicase
EGM64_RS20345	COG0596	Alpha beta hydrolase
EGM64_RS20390	COG0513	Belongs to the DEAD box helicase family
EGM64_RS20405	COG0406	alpha-ribazole phosphatase activity
EGM64_RS20440	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EGM64_RS20465	COG1063	alcohol dehydrogenase
EGM64_RS20475	COG1028	Short-chain dehydrogenase reductase Sdr
EGM64_RS20485	COG1028	Short-chain dehydrogenase reductase Sdr
EGM64_RS20500	COG1403	HNH endonuclease
EGM64_RS20510	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EGM64_RS20515	COG1162	GTPase activity
EGM64_RS20520	COG1733	regulation of RNA biosynthetic process
EGM64_RS20525	COG0183	Belongs to the thiolase family
EGM64_RS20575	COG2326	polyphosphate kinase activity
EGM64_RS20600	COG2020	methyltransferase activity
EGM64_RS20605	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
EGM64_RS20615	COG0653	protein targeting
EGM64_RS20620	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EGM64_RS20635	COG5401	PFAM Sporulation and spore germination
EGM64_RS20640	COG5000	phosphorelay sensor kinase activity
EGM64_RS20640	COG5002	protein histidine kinase activity
EGM64_RS20655	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EGM64_RS20675	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EGM64_RS20680	COG0531	amino acid
EGM64_RS20685	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EGM64_RS20690	COG1482	cell wall glycoprotein biosynthetic process
EGM64_RS20700	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EGM64_RS20730	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
EGM64_RS20730	COG0778	Nitroreductase
EGM64_RS20745	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EGM64_RS20760	COG1316	TRANSCRIPTIONal
EGM64_RS20780	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EGM64_RS20785	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EGM64_RS20800	COG0784	Response regulator, receiver
EGM64_RS20805	COG4251	negative regulation of phosphorylation
EGM64_RS20850	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EGM64_RS20860	COG0424	maF-like protein
EGM64_RS20875	COG4770	biotin carboxylase activity
EGM64_RS20880	COG1366	Belongs to the anti-sigma-factor antagonist family
EGM64_RS20910	COG1522	sequence-specific DNA binding
EGM64_RS20920	COG1012	belongs to the aldehyde dehydrogenase family
EGM64_RS20925	COG1309	transcriptional regulator
EGM64_RS20975	COG0564	pseudouridine synthase activity
EGM64_RS20980	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EGM64_RS20995	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
EGM64_RS20995	COG1473	amidohydrolase
EGM64_RS21000	COG1473	amidohydrolase
EGM64_RS21015	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EGM64_RS21020	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EGM64_RS21025	COG3511	phospholipase C
EGM64_RS21035	COG2304	oxidoreductase activity
EGM64_RS21040	COG2304	oxidoreductase activity
EGM64_RS21070	COG2009	succinate dehydrogenase
EGM64_RS21085	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EGM64_RS21095	COG1595	DNA-templated transcription, initiation
EGM64_RS21100	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EGM64_RS21110	COG1686	Belongs to the peptidase S11 family
EGM64_RS21115	COG2814	Major facilitator Superfamily
EGM64_RS21120	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EGM64_RS21125	COG0402	S-adenosylhomocysteine deaminase activity
EGM64_RS21135	COG1295	ribonuclease BN
EGM64_RS21140	COG0180	Tryptophanyl-tRNA synthetase
EGM64_RS21160	COG2873	o-acetylhomoserine
EGM64_RS21165	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EGM64_RS21190	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EGM64_RS21200	COG1131	(ABC) transporter
EGM64_RS21200	COG0842	Transport permease protein
EGM64_RS21200	COG1716	ATPase activity
EGM64_RS21205	COG1716	ATPase activity
EGM64_RS21205	COG1131	(ABC) transporter
EGM64_RS21205	COG0842	Transport permease protein
EGM64_RS21215	COG1357	PFAM Pentapeptide repeats (8 copies)
EGM64_RS21230	COG2018	Roadblock/LC7 domain
EGM64_RS21235	COG5002	protein histidine kinase activity
EGM64_RS21245	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EGM64_RS21255	COG0587	DNA-directed DNA polymerase activity
EGM64_RS21265	COG1877	trehalose-phosphatase activity
EGM64_RS21265	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EGM64_RS21270	COG2030	dehydratase
EGM64_RS21285	COG0406	alpha-ribazole phosphatase activity
EGM64_RS21325	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EGM64_RS21325	COG0519	Catalyzes the synthesis of GMP from XMP
EGM64_RS21330	COG5651	PPE family
EGM64_RS21370	COG0318	PFAM AMP-dependent synthetase and ligase
EGM64_RS21405	COG1028	Short-chain dehydrogenase reductase Sdr
EGM64_RS21410	COG0318	PFAM AMP-dependent synthetase and ligase
EGM64_RS21425	COG1028	Short-chain dehydrogenase reductase Sdr
EGM64_RS21435	COG2072	flavoprotein involved in K transport
EGM64_RS21440	COG1028	Short-chain dehydrogenase reductase Sdr
EGM64_RS21450	COG0028	Belongs to the TPP enzyme family
EGM64_RS21465	COG2755	lipolytic protein G-D-S-L family
EGM64_RS21465	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EGM64_RS21485	COG3321	synthase
EGM64_RS21485	COG0604	alcohol dehydrogenase
EGM64_RS21495	COG1376	ErfK ybiS ycfS ynhG family protein
EGM64_RS21505	COG0583	DNA-binding transcription factor activity
EGM64_RS21510	COG0028	Belongs to the TPP enzyme family
EGM64_RS21530	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EGM64_RS21540	COG3281	Trehalose synthase
EGM64_RS21560	COG1129	ABC transporter
EGM64_RS21560	COG0842	Transport permease protein
EGM64_RS21575	COG1937	Protein conserved in bacteria
EGM64_RS21585	COG2267	carboxylic ester hydrolase activity
EGM64_RS21605	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGM64_RS21670	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EGM64_RS21700	COG0783	Belongs to the Dps family
EGM64_RS21705	COG1741	Belongs to the pirin family
EGM64_RS21715	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EGM64_RS21730	COG1012	belongs to the aldehyde dehydrogenase family
EGM64_RS21735	COG1028	Short-chain dehydrogenase reductase Sdr
EGM64_RS21775	COG1309	transcriptional regulator
EGM64_RS21825	COG1960	acyl-CoA dehydrogenase activity
EGM64_RS21850	COG2124	cytochrome p450
EGM64_RS21870	COG2072	flavoprotein involved in K transport
EGM64_RS21875	COG0657	acetylesterase activity
EGM64_RS21905	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EGM64_RS21910	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EGM64_RS21935	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EGM64_RS21950	COG1714	RDD family
EGM64_RS21965	COG3619	membrane
EGM64_RS22005	COG2267	carboxylic ester hydrolase activity
EGM64_RS22020	COG1472	Belongs to the glycosyl hydrolase 3 family
EGM64_RS22030	COG4122	O-methyltransferase activity
EGM64_RS22045	COG0129	dihydroxy-acid dehydratase activity
EGM64_RS22050	COG1937	Protein conserved in bacteria
EGM64_RS22055	COG2814	Major facilitator Superfamily
EGM64_RS22060	COG1376	ErfK ybiS ycfS ynhG family protein
EGM64_RS22070	COG0243	molybdopterin cofactor binding
EGM64_RS22095	COG2409	Drug exporters of the RND superfamily
EGM64_RS22105	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EGM64_RS22120	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
EGM64_RS22135	COG1024	Enoyl-CoA hydratase
EGM64_RS22165	COG0657	acetylesterase activity
EGM64_RS22170	COG0657	acetylesterase activity
EGM64_RS22180	COG1024	Enoyl-CoA hydratase
EGM64_RS22195	COG1309	transcriptional regulator
EGM64_RS22205	COG0500	methyltransferase
EGM64_RS22240	COG2801	Transposase and inactivated derivatives
EGM64_RS22240	COG3415	Transposase
EGM64_RS22250	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EGM64_RS22255	COG1012	belongs to the aldehyde dehydrogenase family
EGM64_RS22260	COG0028	Belongs to the TPP enzyme family
EGM64_RS22265	COG0583	DNA-binding transcription factor activity
EGM64_RS22315	COG4981	capsule polysaccharide biosynthetic process
EGM64_RS22330	COG1472	Belongs to the glycosyl hydrolase 3 family
EGM64_RS22345	COG2030	dehydratase
EGM64_RS22350	COG1028	Short-chain dehydrogenase reductase Sdr
EGM64_RS22355	COG0183	Belongs to the thiolase family
EGM64_RS22360	COG1960	acyl-CoA dehydrogenase activity
EGM64_RS22380	COG1053	succinate dehydrogenase
EGM64_RS22400	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EGM64_RS22400	COG2146	nitrite reductase [NAD(P)H] activity
EGM64_RS22435	COG1984	allophanate hydrolase subunit 2
EGM64_RS22440	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EGM64_RS22450	COG1309	transcriptional regulator
EGM64_RS22455	COG2223	nitrite transmembrane transporter activity
EGM64_RS22465	COG0318	PFAM AMP-dependent synthetase and ligase
EGM64_RS22480	COG1960	acyl-CoA dehydrogenase activity
EGM64_RS22495	COG0346	lactoylglutathione lyase activity
EGM64_RS22535	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EGM64_RS22540	COG1120	ATPase activity
EGM64_RS22560	COG1129	ABC transporter
EGM64_RS22580	COG2375	cellular response to nickel ion
EGM64_RS22580	COG1132	(ABC) transporter
EGM64_RS22600	COG0477	Major facilitator Superfamily
EGM64_RS22605	COG2226	methyltransferase
EGM64_RS22605	COG3433	isochorismatase activity
EGM64_RS22605	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EGM64_RS22610	COG2226	methyltransferase
EGM64_RS22610	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EGM64_RS22610	COG3433	isochorismatase activity
EGM64_RS22615	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EGM64_RS22630	COG1937	Protein conserved in bacteria
EGM64_RS22640	COG3547	Transposase (IS116 IS110 IS902 family)
EGM64_RS22660	COG0318	PFAM AMP-dependent synthetase and ligase
EGM64_RS22695	COG3328	transposase activity
EGM64_RS22700	COG3415	Transposase
EGM64_RS22700	COG2801	Transposase and inactivated derivatives
EGM64_RS22725	COG0187	DNA topoisomerase II activity
EGM64_RS22730	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
EGM64_RS22735	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EGM64_RS22740	COG0592	DNA-directed DNA polymerase activity
EGM64_RS22745	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EGM64_RS22755	COG0594	ribonuclease P activity
EGM64_RS22760	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EGM64_RS22765	COG0706	membrane insertase activity
EGM64_RS22775	COG0357	Ribosomal RNA small subunit methyltransferase G
EGM64_RS22780	COG1192	Involved in chromosome partitioning
EGM64_RS22795	COG0860	N-Acetylmuramoyl-L-alanine amidase
EGM64_RS22795	COG3409	Peptidoglycan-binding domain 1 protein
EGM64_RS22815	COG1595	DNA-templated transcription, initiation
EGM64_RS22910	COG1674	ftsk spoiiie
EGM64_RS22925	COG4585	Histidine kinase
EGM64_RS22930	COG2197	response regulator
EGM64_RS22940	COG4638	Rieske (2fe-2S)
EGM64_RS22945	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
EGM64_RS22975	COG3588	fructose-bisphosphate aldolase
EGM64_RS22995	COG1309	transcriptional regulator
EGM64_RS23015	COG1609	Transcriptional regulator
EGM64_RS23025	COG1804	L-carnitine dehydratase bile acid-inducible protein F