locus-tag	class	description
EGA31_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EGA31_RS00010	COG0592	DNA-directed DNA polymerase activity
EGA31_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EGA31_RS00020	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
EGA31_RS00025	COG0187	DNA topoisomerase II activity
EGA31_RS00050	COG2801	Transposase and inactivated derivatives
EGA31_RS00050	COG3415	Transposase
EGA31_RS00055	COG3328	transposase activity
EGA31_RS00105	COG0515	serine threonine protein kinase
EGA31_RS00130	COG1716	ATPase activity
EGA31_RS00170	COG3328	transposase activity
EGA31_RS00205	COG1960	acyl-CoA dehydrogenase activity
EGA31_RS00230	COG0741	lytic transglycosylase activity
EGA31_RS00230	COG0791	NLP P60 protein
EGA31_RS00290	COG0495	leucyl-tRNA aminoacylation
EGA31_RS00310	COG0765	amino acid transport
EGA31_RS00325	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EGA31_RS00325	COG0596	Alpha beta hydrolase
EGA31_RS00370	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EGA31_RS00385	COG0360	Binds together with S18 to 16S ribosomal RNA
EGA31_RS00400	COG0359	binds to the 23S rRNA
EGA31_RS00410	COG0204	Acyl-transferase
EGA31_RS00420	COG1309	transcriptional regulator
EGA31_RS00450	COG1028	Short-chain dehydrogenase reductase Sdr
EGA31_RS00460	COG0277	FAD linked oxidase domain protein
EGA31_RS00500	COG1247	-acetyltransferase
EGA31_RS00520	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EGA31_RS00530	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EGA31_RS00585	COG3328	transposase activity
EGA31_RS00600	COG4974	Belongs to the 'phage' integrase family
EGA31_RS00650	COG1309	transcriptional regulator
EGA31_RS00700	COG0659	secondary active sulfate transmembrane transporter activity
EGA31_RS00705	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGA31_RS00710	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EGA31_RS00730	COG0477	Major facilitator Superfamily
EGA31_RS00740	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EGA31_RS00745	COG0346	lactoylglutathione lyase activity
EGA31_RS00770	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGA31_RS00790	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EGA31_RS00795	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EGA31_RS00810	COG1960	acyl-CoA dehydrogenase activity
EGA31_RS00815	COG1309	transcriptional regulator
EGA31_RS00825	COG1024	Enoyl-CoA hydratase
EGA31_RS00830	COG1309	transcriptional regulator
EGA31_RS00885	COG1404	Belongs to the peptidase S8 family
EGA31_RS00920	COG0067	glutamate synthase
EGA31_RS00920	COG0069	glutamate synthase activity
EGA31_RS00920	COG0070	glutamate synthase
EGA31_RS00940	COG1796	DNA polymerase
EGA31_RS00940	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EGA31_RS00945	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EGA31_RS00950	COG1309	transcriptional regulator
EGA31_RS00955	COG2072	flavoprotein involved in K transport
EGA31_RS00960	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EGA31_RS01010	COG1316	TRANSCRIPTIONal
EGA31_RS01045	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EGA31_RS01100	COG0561	phosphatase activity
EGA31_RS01120	COG1216	Glycosyl transferase, family 2
EGA31_RS01135	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EGA31_RS01145	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
EGA31_RS01150	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
EGA31_RS01155	COG0318	PFAM AMP-dependent synthetase and ligase
EGA31_RS01160	COG3321	synthase
EGA31_RS01160	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
EGA31_RS01160	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EGA31_RS01165	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EGA31_RS01180	COG1960	acyl-CoA dehydrogenase activity
EGA31_RS01235	COG1028	Short-chain dehydrogenase reductase Sdr
EGA31_RS01240	COG0277	FAD linked oxidase domain protein
EGA31_RS01290	COG0604	alcohol dehydrogenase
EGA31_RS01310	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EGA31_RS01330	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EGA31_RS01345	COG2801	Transposase and inactivated derivatives
EGA31_RS01345	COG3415	Transposase
EGA31_RS01360	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EGA31_RS01375	COG0745	RESPONSE REGULATOR receiver
EGA31_RS01380	COG2205	protein histidine kinase activity
EGA31_RS01390	COG2015	COG2015, Alkyl sulfatase and related hydrolases
EGA31_RS01435	COG5416	Lipopolysaccharide assembly protein A domain
EGA31_RS01450	COG1174	glycine betaine transport
EGA31_RS01465	COG0287	Prephenate dehydrogenase
EGA31_RS01475	COG0590	tRNA wobble adenosine to inosine editing
EGA31_RS01560	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EGA31_RS01565	COG2301	Belongs to the HpcH HpaI aldolase family
EGA31_RS01580	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EGA31_RS01590	COG3800	Transcriptional regulator
EGA31_RS01590	COG1396	sequence-specific DNA binding
EGA31_RS01595	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EGA31_RS01600	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EGA31_RS01620	COG3804	dihydrodipicolinate reductase
EGA31_RS01640	COG0596	Alpha beta hydrolase
EGA31_RS01660	COG1793	dna ligase
EGA31_RS01720	COG2032	superoxide dismutase activity
EGA31_RS01745	COG0406	alpha-ribazole phosphatase activity
EGA31_RS01785	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EGA31_RS01785	COG0519	Catalyzes the synthesis of GMP from XMP
EGA31_RS01790	COG5651	PPE family
EGA31_RS01820	COG0842	Transport permease protein
EGA31_RS01820	COG1716	ATPase activity
EGA31_RS01820	COG1131	(ABC) transporter
EGA31_RS01825	COG0842	Transport permease protein
EGA31_RS01825	COG1131	(ABC) transporter
EGA31_RS01825	COG1716	ATPase activity
EGA31_RS01835	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EGA31_RS01850	COG1403	HNH endonuclease
EGA31_RS01860	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EGA31_RS01865	COG2873	o-acetylhomoserine
EGA31_RS01885	COG0180	Tryptophanyl-tRNA synthetase
EGA31_RS01890	COG1295	ribonuclease BN
EGA31_RS01900	COG0402	S-adenosylhomocysteine deaminase activity
EGA31_RS01905	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EGA31_RS01915	COG1686	Belongs to the peptidase S11 family
EGA31_RS01925	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EGA31_RS01930	COG1595	DNA-templated transcription, initiation
EGA31_RS01940	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EGA31_RS01955	COG2009	succinate dehydrogenase
EGA31_RS01995	COG2304	oxidoreductase activity
EGA31_RS02000	COG2304	oxidoreductase activity
EGA31_RS02010	COG3511	phospholipase C
EGA31_RS02015	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EGA31_RS02020	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EGA31_RS02035	COG1473	amidohydrolase
EGA31_RS02040	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
EGA31_RS02040	COG1473	amidohydrolase
EGA31_RS02055	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EGA31_RS02060	COG0564	pseudouridine synthase activity
EGA31_RS02110	COG1309	transcriptional regulator
EGA31_RS02115	COG1012	belongs to the aldehyde dehydrogenase family
EGA31_RS02125	COG1522	sequence-specific DNA binding
EGA31_RS02155	COG1366	Belongs to the anti-sigma-factor antagonist family
EGA31_RS02160	COG4770	biotin carboxylase activity
EGA31_RS02175	COG0424	maF-like protein
EGA31_RS02185	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EGA31_RS02230	COG4251	negative regulation of phosphorylation
EGA31_RS02235	COG0784	Response regulator, receiver
EGA31_RS02250	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EGA31_RS02255	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EGA31_RS02275	COG1316	TRANSCRIPTIONal
EGA31_RS02290	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EGA31_RS02305	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
EGA31_RS02305	COG0778	Nitroreductase
EGA31_RS02335	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EGA31_RS02345	COG1482	cell wall glycoprotein biosynthetic process
EGA31_RS02350	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EGA31_RS02355	COG0531	amino acid
EGA31_RS02360	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EGA31_RS02380	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EGA31_RS02395	COG5002	protein histidine kinase activity
EGA31_RS02395	COG5000	phosphorelay sensor kinase activity
EGA31_RS02400	COG5401	PFAM Sporulation and spore germination
EGA31_RS02415	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EGA31_RS02420	COG0653	protein targeting
EGA31_RS02430	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
EGA31_RS02435	COG2020	methyltransferase activity
EGA31_RS02460	COG2326	polyphosphate kinase activity
EGA31_RS02485	COG1309	transcriptional regulator
EGA31_RS02510	COG0183	Belongs to the thiolase family
EGA31_RS02515	COG1733	regulation of RNA biosynthetic process
EGA31_RS02520	COG1162	GTPase activity
EGA31_RS02525	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EGA31_RS02535	COG1403	HNH endonuclease
EGA31_RS02550	COG1028	Short-chain dehydrogenase reductase Sdr
EGA31_RS02560	COG1028	Short-chain dehydrogenase reductase Sdr
EGA31_RS02570	COG1063	alcohol dehydrogenase
EGA31_RS02595	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EGA31_RS02630	COG0406	alpha-ribazole phosphatase activity
EGA31_RS02645	COG0513	Belongs to the DEAD box helicase family
EGA31_RS02690	COG0596	Alpha beta hydrolase
EGA31_RS02705	COG0210	DNA helicase
EGA31_RS02735	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EGA31_RS02750	COG3480	Lon protease (S16) C-terminal proteolytic domain
EGA31_RS02770	COG0386	Belongs to the glutathione peroxidase family
EGA31_RS02780	COG3706	GGDEF domain
EGA31_RS02870	COG2197	response regulator
EGA31_RS02875	COG4585	Histidine kinase
EGA31_RS02900	COG3707	response regulator
EGA31_RS02910	COG0789	Transcriptional regulator
EGA31_RS02970	COG1573	uracil-dna glycosylase
EGA31_RS02975	COG0028	Belongs to the TPP enzyme family
EGA31_RS02980	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EGA31_RS02990	COG1028	Short-chain dehydrogenase reductase Sdr
EGA31_RS03000	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EGA31_RS03005	COG2192	nodulation
EGA31_RS03010	COG1088	dTDP-glucose 4,6-dehydratase activity
EGA31_RS03020	COG0297	glycogen (starch) synthase activity
EGA31_RS03060	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EGA31_RS03085	COG2201	protein-glutamate methylesterase activity
EGA31_RS03100	COG2201	protein-glutamate methylesterase activity
EGA31_RS03125	COG0477	Major facilitator Superfamily
EGA31_RS03175	COG0714	Associated with various cellular activities
EGA31_RS03190	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EGA31_RS03195	COG1309	transcriptional regulator
EGA31_RS03230	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EGA31_RS03235	COG1034	ATP synthesis coupled electron transport
EGA31_RS03255	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EGA31_RS03295	COG1960	acyl-CoA dehydrogenase activity
EGA31_RS03305	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EGA31_RS03310	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EGA31_RS03330	COG1960	acyl-CoA dehydrogenase activity
EGA31_RS03340	COG0483	inositol monophosphate 1-phosphatase activity
EGA31_RS03385	COG0493	'glutamate synthase
EGA31_RS03395	COG0668	transmembrane transport
EGA31_RS03405	COG2884	Cell division ATP-binding protein ftsE
EGA31_RS03410	COG2177	Part of the ABC transporter FtsEX involved in
EGA31_RS03415	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EGA31_RS03435	COG3328	transposase activity
EGA31_RS03455	COG1819	glycosyl
EGA31_RS03480	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EGA31_RS03510	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EGA31_RS03520	COG2301	Belongs to the HpcH HpaI aldolase family
EGA31_RS03540	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EGA31_RS03545	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EGA31_RS03555	COG0477	Major facilitator Superfamily
EGA31_RS03570	COG3654	unkown
EGA31_RS03590	COG4638	Rieske (2fe-2S)
EGA31_RS03620	COG4638	Rieske (2fe-2S)
EGA31_RS03630	COG2175	clavaminate synthase activity
EGA31_RS03640	COG0148	phosphopyruvate hydratase activity
EGA31_RS03675	COG2076	Multidrug Resistance protein
EGA31_RS03685	COG1028	Short-chain dehydrogenase reductase Sdr
EGA31_RS03710	COG1024	Enoyl-CoA hydratase
EGA31_RS03715	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGA31_RS03720	COG0443	Heat shock 70 kDa protein
EGA31_RS03725	COG1966	Carbon starvation protein
EGA31_RS03730	COG1793	dna ligase
EGA31_RS03740	COG1960	acyl-CoA dehydrogenase activity
EGA31_RS03755	COG2186	Transcriptional regulator
EGA31_RS03820	COG1309	transcriptional regulator
EGA31_RS03825	COG2072	flavoprotein involved in K transport
EGA31_RS03830	COG1309	transcriptional regulator
EGA31_RS03835	COG2226	methyltransferase
EGA31_RS03835	COG2867	negative regulation of translational initiation
EGA31_RS03840	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EGA31_RS03860	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EGA31_RS03870	COG1119	ATPase activity
EGA31_RS03880	COG1024	Enoyl-CoA hydratase
EGA31_RS03905	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EGA31_RS03910	COG0110	maltose O-acetyltransferase activity
EGA31_RS03920	COG0415	Belongs to the DNA photolyase family
EGA31_RS03930	COG2409	Drug exporters of the RND superfamily
EGA31_RS03935	COG1304	FMN binding
EGA31_RS03940	COG3415	Transposase
EGA31_RS03940	COG2801	Transposase and inactivated derivatives
EGA31_RS03990	COG0142	geranyltranstransferase activity
EGA31_RS04055	COG0482	sulfurtransferase activity
EGA31_RS04075	COG0626	cystathionine gamma-synthase activity
EGA31_RS04115	COG0154	amidase activity
EGA31_RS04120	COG0205	6-phosphofructokinase activity
EGA31_RS04125	COG1192	Involved in chromosome partitioning
EGA31_RS04140	COG2259	Doxx family
EGA31_RS04165	COG0655	NAD(P)H dehydrogenase (quinone) activity
EGA31_RS04180	COG0473	3-isopropylmalate dehydrogenase activity
EGA31_RS04190	COG0179	Fumarylacetoacetate (FAA) hydrolase
EGA31_RS04195	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EGA31_RS04220	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EGA31_RS04225	COG0066	3-isopropylmalate dehydratase activity
EGA31_RS04240	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EGA31_RS04245	COG1920	GTP binding
EGA31_RS04250	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EGA31_RS04255	COG1181	Belongs to the D-alanine--D-alanine ligase family
EGA31_RS04270	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EGA31_RS04310	COG1461	Dihydroxyacetone kinase
EGA31_RS04335	COG0657	acetylesterase activity
EGA31_RS04350	COG0742	ribosomal rna small subunit methyltransferase
EGA31_RS04365	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EGA31_RS04370	COG0701	Predicted permease
EGA31_RS04390	COG0571	ribonuclease III activity
EGA31_RS04395	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EGA31_RS04400	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EGA31_RS04415	COG1196	nuclear chromosome segregation
EGA31_RS04435	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
EGA31_RS04470	COG1686	Belongs to the peptidase S11 family
EGA31_RS04490	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EGA31_RS04495	COG0336	Belongs to the RNA methyltransferase TrmD family
EGA31_RS04515	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EGA31_RS04535	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EGA31_RS04545	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EGA31_RS04610	COG0052	Belongs to the universal ribosomal protein uS2 family
EGA31_RS04615	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EGA31_RS04620	COG0154	amidase activity
EGA31_RS04635	COG1028	Short-chain dehydrogenase reductase Sdr
EGA31_RS04650	COG0745	RESPONSE REGULATOR receiver
EGA31_RS04670	COG0575	Belongs to the CDS family
EGA31_RS04675	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EGA31_RS04695	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EGA31_RS04700	COG0750	zinc metalloprotease
EGA31_RS04705	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EGA31_RS04730	COG1492	cobalamin metabolic process
EGA31_RS04745	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EGA31_RS04750	COG1012	belongs to the aldehyde dehydrogenase family
EGA31_RS04755	COG1028	Short-chain dehydrogenase reductase Sdr
EGA31_RS04775	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
EGA31_RS04790	COG0579	oxidoreductase
EGA31_RS04820	COG1648	precorrin-2 dehydrogenase activity
EGA31_RS04820	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EGA31_RS04830	COG4552	Acetyltransferase involved in intracellular survival and related
EGA31_RS04835	COG0442	prolyl-tRNA aminoacylation
EGA31_RS04850	COG0779	Required for maturation of 30S ribosomal subunits
EGA31_RS04865	COG0481	GTPase activity
EGA31_RS04875	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EGA31_RS04910	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EGA31_RS04915	COG2977	Belongs to the P-Pant transferase superfamily
EGA31_RS04920	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EGA31_RS04925	COG0183	Belongs to the thiolase family
EGA31_RS04930	COG1960	acyl-CoA dehydrogenase activity
EGA31_RS04950	COG1185	polyribonucleotide nucleotidyltransferase activity
EGA31_RS04965	COG0686	Belongs to the AlaDH PNT family
EGA31_RS05010	COG1403	HNH endonuclease
EGA31_RS05020	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EGA31_RS05040	COG0318	PFAM AMP-dependent synthetase and ligase
EGA31_RS05045	COG4770	biotin carboxylase activity
EGA31_RS05055	COG1028	Short-chain dehydrogenase reductase Sdr
EGA31_RS05070	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EGA31_RS05085	COG3214	Protein conserved in bacteria
EGA31_RS05100	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EGA31_RS05125	COG1674	ftsk spoiiie
EGA31_RS05130	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EGA31_RS05145	COG1842	Phage shock protein A
EGA31_RS05160	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
EGA31_RS05195	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EGA31_RS05205	COG1196	nuclear chromosome segregation
EGA31_RS05220	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EGA31_RS05225	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EGA31_RS05230	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EGA31_RS05235	COG1960	acyl-CoA dehydrogenase activity
EGA31_RS05255	COG1388	LysM domain
EGA31_RS05265	COG4044	May play a role in the intracellular transport of hydrophobic ligands
EGA31_RS05350	COG0483	inositol monophosphate 1-phosphatase activity
EGA31_RS05400	COG0569	domain protein
EGA31_RS05405	COG0531	amino acid
EGA31_RS05410	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EGA31_RS05415	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EGA31_RS05425	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EGA31_RS05445	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EGA31_RS05470	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EGA31_RS05535	COG1012	belongs to the aldehyde dehydrogenase family
EGA31_RS05545	COG1028	Short-chain dehydrogenase reductase Sdr
EGA31_RS05555	COG1309	transcriptional regulator
EGA31_RS05585	COG4221	oxidoreductase activity
EGA31_RS05740	COG4974	Belongs to the 'phage' integrase family
EGA31_RS05780	COG1024	Enoyl-CoA hydratase
EGA31_RS05795	COG1028	Short-chain dehydrogenase reductase Sdr
EGA31_RS05800	COG0753	catalase activity
EGA31_RS05810	COG1366	Belongs to the anti-sigma-factor antagonist family
EGA31_RS05830	COG1414	Transcriptional regulator
EGA31_RS05870	COG3485	protocatechuate 3,4-dioxygenase
EGA31_RS05875	COG3485	protocatechuate 3,4-dioxygenase
EGA31_RS05925	COG4762	Protein conserved in bacteria
EGA31_RS05930	COG0667	Aldo Keto reductase
EGA31_RS05945	COG0025	NhaP-type Na H and K H
EGA31_RS05950	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EGA31_RS05985	COG1946	Acyl-CoA thioesterase
EGA31_RS05990	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EGA31_RS06000	COG1331	Highly conserved protein containing a thioredoxin domain
EGA31_RS06030	COG0572	uridine kinase
EGA31_RS06045	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EGA31_RS06085	COG2272	Belongs to the type-B carboxylesterase lipase family
EGA31_RS06100	COG1570	exodeoxyribonuclease VII activity
EGA31_RS06110	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EGA31_RS06120	COG0012	GTP binding
EGA31_RS06195	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EGA31_RS06210	COG0596	Alpha beta hydrolase
EGA31_RS06225	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EGA31_RS06225	COG0574	Belongs to the PEP-utilizing enzyme family
EGA31_RS06240	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EGA31_RS06255	COG1309	transcriptional regulator
EGA31_RS06265	COG1960	acyl-CoA dehydrogenase activity
EGA31_RS06270	COG1960	acyl-CoA dehydrogenase activity
EGA31_RS06280	COG0714	Associated with various cellular activities
EGA31_RS06295	COG1028	Short-chain dehydrogenase reductase Sdr
EGA31_RS06300	COG2124	cytochrome p450
EGA31_RS06310	COG0183	Belongs to the thiolase family
EGA31_RS06315	COG1024	Enoyl-CoA hydratase
EGA31_RS06335	COG0702	epimerase
EGA31_RS06350	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EGA31_RS06370	COG2409	Drug exporters of the RND superfamily
EGA31_RS06380	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EGA31_RS06395	COG3467	pyridoxamine 5'-phosphate
EGA31_RS06430	COG2154	pterin-4-alpha-carbinolamine dehydratase
EGA31_RS06450	COG1140	nitrate reductase beta subunit
EGA31_RS06465	COG1217	gtp-binding protein TYPA
EGA31_RS06480	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EGA31_RS06490	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
EGA31_RS06505	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EGA31_RS06515	COG0531	amino acid
EGA31_RS06555	COG0529	Catalyzes the synthesis of activated sulfate
EGA31_RS06560	COG2046	Belongs to the sulfate adenylyltransferase family
EGA31_RS06570	COG0318	PFAM AMP-dependent synthetase and ligase
EGA31_RS06585	COG1012	belongs to the aldehyde dehydrogenase family
EGA31_RS06590	COG0506	proline dehydrogenase activity
EGA31_RS06610	COG1960	acyl-CoA dehydrogenase activity
EGA31_RS06625	COG1960	acyl-CoA dehydrogenase activity
EGA31_RS06630	COG2124	cytochrome p450
EGA31_RS06640	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EGA31_RS06650	COG0318	PFAM AMP-dependent synthetase and ligase
EGA31_RS06655	COG0477	Major facilitator Superfamily
EGA31_RS06695	COG1611	Belongs to the LOG family
EGA31_RS06700	COG0318	PFAM AMP-dependent synthetase and ligase
EGA31_RS06710	COG0463	Glycosyl transferase, family 2
EGA31_RS06720	COG0519	Catalyzes the synthesis of GMP from XMP
EGA31_RS06740	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EGA31_RS06755	COG3559	Exporter of polyketide antibiotics
EGA31_RS06760	COG1131	(ABC) transporter
EGA31_RS06780	COG2963	transposase activity
EGA31_RS06795	COG2072	flavoprotein involved in K transport
EGA31_RS06805	COG0300	oxidoreductase activity
EGA31_RS06810	COG0657	acetylesterase activity
EGA31_RS06835	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EGA31_RS06860	COG0318	PFAM AMP-dependent synthetase and ligase
EGA31_RS06890	COG1309	transcriptional regulator
EGA31_RS06940	COG2124	cytochrome p450
EGA31_RS06985	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EGA31_RS07015	COG0789	Transcriptional regulator
EGA31_RS07070	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EGA31_RS07075	COG1021	2,3-dihydroxybenzoate-AMP ligase
EGA31_RS07080	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EGA31_RS07110	COG3486	L-lysine 6-monooxygenase (NADPH) activity
EGA31_RS07130	COG1595	DNA-templated transcription, initiation
EGA31_RS07145	COG1420	regulation of RNA biosynthetic process
EGA31_RS07150	COG0484	heat shock protein binding
EGA31_RS07165	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EGA31_RS07235	COG3328	transposase activity
EGA31_RS07275	COG0657	acetylesterase activity
EGA31_RS07280	COG0318	PFAM AMP-dependent synthetase and ligase
EGA31_RS07315	COG0149	triose-phosphate isomerase activity
EGA31_RS07330	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
EGA31_RS07340	COG0667	Aldo Keto reductase
EGA31_RS07345	COG0123	including yeast histone deacetylase and acetoin utilization protein
EGA31_RS07370	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EGA31_RS07380	COG0109	protoheme IX farnesyltransferase activity
EGA31_RS07430	COG0396	ATPase activity
EGA31_RS07445	COG2151	metal-sulfur cluster biosynthetic enzyme
EGA31_RS07465	COG1960	acyl-CoA dehydrogenase activity
EGA31_RS07470	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EGA31_RS07480	COG0488	(ABC) transporter
EGA31_RS07490	COG1309	transcriptional regulator
EGA31_RS07505	COG0791	NLP P60 protein
EGA31_RS07505	COG3883	PFAM NLP P60 protein
EGA31_RS07515	COG0714	Associated with various cellular activities
EGA31_RS07525	COG2304	oxidoreductase activity
EGA31_RS07545	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EGA31_RS07595	COG0745	RESPONSE REGULATOR receiver
EGA31_RS07600	COG5002	protein histidine kinase activity
EGA31_RS07635	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EGA31_RS07710	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EGA31_RS07720	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
EGA31_RS07725	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EGA31_RS07790	COG2070	2-Nitropropane dioxygenase
EGA31_RS07805	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EGA31_RS07820	COG0252	asparaginase activity
EGA31_RS07840	COG2346	COG2346, Truncated hemoglobins
EGA31_RS07900	COG0671	phosphoesterase, PA-phosphatase related
EGA31_RS07935	COG0791	NLP P60 protein
EGA31_RS07935	COG3883	PFAM NLP P60 protein
EGA31_RS07945	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EGA31_RS07950	COG0156	8-amino-7-oxononanoate synthase activity
EGA31_RS07965	COG0668	transmembrane transport
EGA31_RS07995	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EGA31_RS08015	COG3547	Transposase (IS116 IS110 IS902 family)
EGA31_RS08030	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EGA31_RS08035	COG0157	Belongs to the NadC ModD family
EGA31_RS08045	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EGA31_RS08050	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EGA31_RS08060	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EGA31_RS08065	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EGA31_RS08070	COG0483	inositol monophosphate 1-phosphatase activity
EGA31_RS08075	COG0107	imidazoleglycerol-phosphate synthase activity
EGA31_RS08080	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EGA31_RS08085	COG0387	Pfam Sodium calcium exchanger
EGA31_RS08135	COG1946	Acyl-CoA thioesterase
EGA31_RS08145	COG1132	(ABC) transporter
EGA31_RS08150	COG4988	ABC transporter
EGA31_RS08155	COG1294	oxidase, subunit
EGA31_RS08160	COG1271	oxidase subunit
EGA31_RS08190	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EGA31_RS08210	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
EGA31_RS08220	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EGA31_RS08220	COG0237	dephospho-CoA kinase activity
EGA31_RS08230	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EGA31_RS08245	COG0842	Transport permease protein
EGA31_RS08245	COG1716	ATPase activity
EGA31_RS08245	COG1131	(ABC) transporter
EGA31_RS08280	COG1285	pathogenesis
EGA31_RS08355	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EGA31_RS08355	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EGA31_RS08395	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EGA31_RS08400	COG0072	phenylalanine-tRNA ligase activity
EGA31_RS08400	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EGA31_RS08405	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EGA31_RS08410	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EGA31_RS08415	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EGA31_RS08425	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EGA31_RS08430	COG1438	arginine binding
EGA31_RS08435	COG0137	argininosuccinate synthase activity
EGA31_RS08440	COG0165	Argininosuccinate lyase
EGA31_RS08470	COG0488	(ABC) transporter
EGA31_RS08475	COG3707	response regulator
EGA31_RS08480	COG0583	DNA-binding transcription factor activity
EGA31_RS08500	COG1028	Short-chain dehydrogenase reductase Sdr
EGA31_RS08505	COG1028	Short-chain dehydrogenase reductase Sdr
EGA31_RS08510	COG4948	Mandelate Racemase Muconate Lactonizing
EGA31_RS08515	COG0300	oxidoreductase activity
EGA31_RS08550	COG2835	tetraacyldisaccharide 4'-kinase activity
EGA31_RS08555	COG1309	transcriptional regulator
EGA31_RS08565	COG1131	(ABC) transporter
EGA31_RS08575	COG2094	Belongs to the DNA glycosylase MPG family
EGA31_RS08580	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EGA31_RS08595	COG0647	UMP catabolic process
EGA31_RS08610	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EGA31_RS08635	COG0494	nUDIX hydrolase
EGA31_RS08660	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EGA31_RS08670	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EGA31_RS08675	COG1160	GTP binding
EGA31_RS08705	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EGA31_RS08715	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EGA31_RS08715	COG0189	ligase activity
EGA31_RS08720	COG2271	Major facilitator Superfamily
EGA31_RS08740	COG2132	Multicopper oxidase
EGA31_RS08765	COG1403	HNH endonuclease
EGA31_RS08770	COG0318	PFAM AMP-dependent synthetase and ligase
EGA31_RS08775	COG2072	flavoprotein involved in K transport
EGA31_RS08800	COG1960	acyl-CoA dehydrogenase activity
EGA31_RS08805	COG1960	acyl-CoA dehydrogenase activity
EGA31_RS08810	COG0842	Transport permease protein
EGA31_RS08810	COG1131	(ABC) transporter
EGA31_RS08810	COG1716	ATPase activity
EGA31_RS08815	COG0657	acetylesterase activity
EGA31_RS08820	COG1028	Short-chain dehydrogenase reductase Sdr
EGA31_RS08840	COG2267	carboxylic ester hydrolase activity
EGA31_RS08850	COG2072	flavoprotein involved in K transport
EGA31_RS08865	COG0346	lactoylglutathione lyase activity
EGA31_RS08880	COG0657	acetylesterase activity
EGA31_RS08895	COG1028	Short-chain dehydrogenase reductase Sdr
EGA31_RS08900	COG2072	flavoprotein involved in K transport
EGA31_RS08915	COG0657	acetylesterase activity
EGA31_RS08925	COG1028	Short-chain dehydrogenase reductase Sdr
EGA31_RS08930	COG1028	Short-chain dehydrogenase reductase Sdr
EGA31_RS08945	COG1053	succinate dehydrogenase
EGA31_RS08975	COG0318	PFAM AMP-dependent synthetase and ligase
EGA31_RS08980	COG0235	Class ii aldolase
EGA31_RS08995	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EGA31_RS09035	COG1028	Short-chain dehydrogenase reductase Sdr
EGA31_RS09050	COG4221	oxidoreductase activity
EGA31_RS09065	COG1403	HNH endonuclease
EGA31_RS09080	COG4221	oxidoreductase activity
EGA31_RS09140	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EGA31_RS09155	COG1053	succinate dehydrogenase
EGA31_RS09195	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EGA31_RS09235	COG5651	PPE family
EGA31_RS09245	COG5651	PPE family
EGA31_RS09275	COG1404	Belongs to the peptidase S8 family
EGA31_RS09290	COG0657	acetylesterase activity
EGA31_RS09335	COG5651	PPE family
EGA31_RS09345	COG1285	pathogenesis
EGA31_RS09375	COG1053	succinate dehydrogenase
EGA31_RS09440	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EGA31_RS09440	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EGA31_RS09460	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EGA31_RS09465	COG1253	flavin adenine dinucleotide binding
EGA31_RS09470	COG1253	flavin adenine dinucleotide binding
EGA31_RS09475	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EGA31_RS09480	COG1960	acyl-CoA dehydrogenase activity
EGA31_RS09485	COG0318	PFAM AMP-dependent synthetase and ligase
EGA31_RS09500	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EGA31_RS09520	COG1252	NADH dehydrogenase
EGA31_RS09585	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EGA31_RS09590	COG0243	molybdopterin cofactor binding
EGA31_RS09600	COG2223	nitrite transmembrane transporter activity
EGA31_RS09610	COG1716	ATPase activity
EGA31_RS09610	COG1131	(ABC) transporter
EGA31_RS09610	COG0842	Transport permease protein
EGA31_RS09630	COG1522	sequence-specific DNA binding
EGA31_RS09635	COG1834	amidinotransferase
EGA31_RS09645	COG0531	amino acid
EGA31_RS09655	COG0395	ABC-type sugar transport system, permease component
EGA31_RS09660	COG1175	transmembrane transport
EGA31_RS09705	COG1012	belongs to the aldehyde dehydrogenase family
EGA31_RS09715	COG0563	adenylate kinase activity
EGA31_RS09720	COG2814	Major facilitator Superfamily
EGA31_RS09750	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EGA31_RS09755	COG2226	methyltransferase
EGA31_RS09805	COG2239	Acts as a magnesium transporter
EGA31_RS09820	COG0697	spore germination
EGA31_RS09845	COG0596	Alpha beta hydrolase
EGA31_RS09855	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EGA31_RS09860	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGA31_RS09875	COG2124	cytochrome p450
EGA31_RS09880	COG3547	Transposase (IS116 IS110 IS902 family)
EGA31_RS09905	COG0438	transferase activity, transferring glycosyl groups
EGA31_RS09910	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EGA31_RS09925	COG0657	acetylesterase activity
EGA31_RS09935	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EGA31_RS09955	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EGA31_RS10000	COG1487	ribonuclease activity
EGA31_RS10030	COG0860	N-Acetylmuramoyl-L-alanine amidase
EGA31_RS10045	COG2072	flavoprotein involved in K transport
EGA31_RS10105	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EGA31_RS10135	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EGA31_RS10155	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EGA31_RS10200	COG0596	Alpha beta hydrolase
EGA31_RS10210	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
EGA31_RS10300	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EGA31_RS10355	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EGA31_RS10360	COG0321	lipoyl(octanoyl) transferase activity
EGA31_RS10395	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EGA31_RS10405	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EGA31_RS10410	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EGA31_RS10415	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
EGA31_RS10420	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
EGA31_RS10450	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EGA31_RS10465	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EGA31_RS10505	COG1845	cytochrome c oxidase, subunit III
EGA31_RS10510	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EGA31_RS10540	COG1022	Amp-dependent synthetase and ligase
EGA31_RS10555	COG0003	Pfam Anion-transporting ATPase
EGA31_RS10585	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
EGA31_RS10590	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EGA31_RS10610	COG0142	geranyltranstransferase activity
EGA31_RS10640	COG0275	rRNA processing
EGA31_RS10650	COG0768	penicillin binding
EGA31_RS10655	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EGA31_RS10670	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EGA31_RS10680	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EGA31_RS10685	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EGA31_RS10700	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EGA31_RS10750	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EGA31_RS10760	COG1403	HNH endonuclease
EGA31_RS10765	COG0167	dihydroorotate dehydrogenase activity
EGA31_RS10800	COG1218	3'(2'),5'-bisphosphate nucleotidase
EGA31_RS10810	COG0215	cysteine-tRNA ligase activity
EGA31_RS10825	COG0028	Belongs to the TPP enzyme family
EGA31_RS10835	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EGA31_RS10845	COG0604	alcohol dehydrogenase
EGA31_RS10845	COG1028	Short-chain dehydrogenase reductase Sdr
EGA31_RS10845	COG3321	synthase
EGA31_RS10865	COG0318	PFAM AMP-dependent synthetase and ligase
EGA31_RS10870	COG1028	Short-chain dehydrogenase reductase Sdr
EGA31_RS10880	COG1410	methionine synthase
EGA31_RS10880	COG0646	methionine synthase
EGA31_RS10925	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EGA31_RS11000	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
EGA31_RS11020	COG2378	regulation of single-species biofilm formation
EGA31_RS11055	COG2826	transposase and inactivated derivatives, IS30 family
EGA31_RS11170	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EGA31_RS11200	COG0412	Dienelactone hydrolase
EGA31_RS11210	COG1574	metal-dependent hydrolase with the TIM-barrel fold
EGA31_RS11235	COG0604	alcohol dehydrogenase
EGA31_RS11235	COG3321	synthase
EGA31_RS11265	COG0714	Associated with various cellular activities
EGA31_RS11325	COG3265	gluconokinase activity
EGA31_RS11345	COG1335	isochorismatase
EGA31_RS11370	COG1595	DNA-templated transcription, initiation
EGA31_RS11380	COG1175	transmembrane transport
EGA31_RS11385	COG0395	ABC-type sugar transport system, permease component
EGA31_RS11390	COG3842	ATPase activity
EGA31_RS11395	COG1752	Esterase of the alpha-beta hydrolase superfamily
EGA31_RS11445	COG0753	catalase activity
EGA31_RS11475	COG1960	acyl-CoA dehydrogenase activity
EGA31_RS11490	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EGA31_RS11495	COG0667	Aldo Keto reductase
EGA31_RS11590	COG1028	Short-chain dehydrogenase reductase Sdr
EGA31_RS11600	COG0183	Belongs to the thiolase family
EGA31_RS11605	COG1960	acyl-CoA dehydrogenase activity
EGA31_RS11610	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EGA31_RS11615	COG1309	transcriptional regulator
EGA31_RS11620	COG2267	carboxylic ester hydrolase activity
EGA31_RS11635	COG1028	Short-chain dehydrogenase reductase Sdr
EGA31_RS11680	COG0301	tRNA thio-modification
EGA31_RS11690	COG0789	Transcriptional regulator
EGA31_RS11700	COG0484	heat shock protein binding
EGA31_RS11710	COG0545	Peptidyl-prolyl cis-trans isomerase
EGA31_RS11715	COG1028	Short-chain dehydrogenase reductase Sdr
EGA31_RS11735	COG2301	Belongs to the HpcH HpaI aldolase family
EGA31_RS11765	COG1643	Atp-dependent helicase
EGA31_RS11780	COG1024	Enoyl-CoA hydratase
EGA31_RS11825	COG0723	plastoquinol--plastocyanin reductase activity
EGA31_RS11835	COG1376	ErfK ybiS ycfS ynhG family protein
EGA31_RS11845	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
EGA31_RS11850	COG3757	hydrolase, family 25
EGA31_RS11855	COG0438	transferase activity, transferring glycosyl groups
EGA31_RS11860	COG2226	methyltransferase
EGA31_RS11890	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EGA31_RS11935	COG4977	sequence-specific DNA binding
EGA31_RS11990	COG0640	Transcriptional regulator
EGA31_RS12010	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
EGA31_RS12070	COG1950	PFAM Membrane protein of
EGA31_RS12080	COG2814	Major facilitator Superfamily
EGA31_RS12085	COG1058	Belongs to the CinA family
EGA31_RS12085	COG1546	Belongs to the CinA family
EGA31_RS12095	COG1490	D-aminoacyl-tRNA deacylase activity
EGA31_RS12100	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EGA31_RS12105	COG1063	alcohol dehydrogenase
EGA31_RS12115	COG1403	HNH endonuclease
EGA31_RS12120	COG2070	2-Nitropropane dioxygenase
EGA31_RS12175	COG1652	LysM domain
EGA31_RS12215	COG0174	glutamine synthetase
EGA31_RS12225	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EGA31_RS12235	COG2193	ferroxidase activity
EGA31_RS12245	COG1024	Enoyl-CoA hydratase
EGA31_RS12270	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EGA31_RS12325	COG0183	Belongs to the thiolase family
EGA31_RS12330	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EGA31_RS12335	COG1968	undecaprenyl-diphosphatase activity
EGA31_RS12340	COG4221	oxidoreductase activity
EGA31_RS12345	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
EGA31_RS12390	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EGA31_RS12415	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EGA31_RS12420	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EGA31_RS12425	COG4424	Sulfotransferase
EGA31_RS12430	COG2855	membrane
EGA31_RS12435	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EGA31_RS12455	COG1045	serine acetyltransferase
EGA31_RS12470	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGA31_RS12520	COG0423	glycine-tRNA ligase activity
EGA31_RS12545	COG1381	Involved in DNA repair and RecF pathway recombination
EGA31_RS12555	COG1982	Orn Lys Arg decarboxylase major
EGA31_RS12560	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EGA31_RS12590	COG3328	transposase activity
EGA31_RS12605	COG1660	Displays ATPase and GTPase activities
EGA31_RS12610	COG0322	excinuclease ABC activity
EGA31_RS12635	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EGA31_RS12675	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EGA31_RS12700	COG0657	acetylesterase activity
EGA31_RS12705	COG2072	flavoprotein involved in K transport
EGA31_RS12710	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EGA31_RS12720	COG1758	RNA polymerase activity
EGA31_RS12725	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
EGA31_RS12740	COG0284	orotidine-5'-phosphate decarboxylase activity
EGA31_RS12750	COG0505	Belongs to the CarA family
EGA31_RS12770	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EGA31_RS12780	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EGA31_RS12785	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EGA31_RS12810	COG2188	Transcriptional regulator
EGA31_RS12825	COG0745	RESPONSE REGULATOR receiver
EGA31_RS12830	COG2205	protein histidine kinase activity
EGA31_RS12860	COG0006	proline dipeptidase activity
EGA31_RS12875	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EGA31_RS12885	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EGA31_RS12895	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EGA31_RS12920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGA31_RS12925	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGA31_RS12935	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EGA31_RS12940	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EGA31_RS12945	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EGA31_RS12955	COG0432	Pfam Uncharacterised protein family UPF0047
EGA31_RS13030	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EGA31_RS13050	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EGA31_RS13055	COG0235	Class ii aldolase
EGA31_RS13060	COG1396	sequence-specific DNA binding
EGA31_RS13080	COG1403	HNH endonuclease
EGA31_RS13090	COG0124	histidyl-tRNA synthetase
EGA31_RS13095	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EGA31_RS13110	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EGA31_RS13115	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EGA31_RS13120	COG0747	negative chemotaxis
EGA31_RS13125	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EGA31_RS13130	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EGA31_RS13145	COG1022	Amp-dependent synthetase and ligase
EGA31_RS13145	COG3320	Male sterility
EGA31_RS13195	COG3766	membrane
EGA31_RS13245	COG0657	acetylesterase activity
EGA31_RS13255	COG0183	Belongs to the thiolase family
EGA31_RS13265	COG1024	Enoyl-CoA hydratase
EGA31_RS13305	COG0121	glutamine amidotransferase
EGA31_RS13315	COG0318	PFAM AMP-dependent synthetase and ligase
EGA31_RS13320	COG3391	amine dehydrogenase activity
EGA31_RS13365	COG0745	RESPONSE REGULATOR receiver
EGA31_RS13370	COG2205	protein histidine kinase activity
EGA31_RS13385	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EGA31_RS13390	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EGA31_RS13395	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
EGA31_RS13440	COG3956	TIGRFAM MazG family protein
EGA31_RS13465	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EGA31_RS13475	COG1393	Belongs to the ArsC family
EGA31_RS13490	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EGA31_RS13495	COG0193	aminoacyl-tRNA hydrolase activity
EGA31_RS13510	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EGA31_RS13515	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EGA31_RS13525	COG0084	hydrolase, TatD family'
EGA31_RS13565	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
EGA31_RS13580	COG0438	transferase activity, transferring glycosyl groups
EGA31_RS13620	COG0297	glycogen (starch) synthase activity
EGA31_RS13620	COG0438	transferase activity, transferring glycosyl groups
EGA31_RS13665	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EGA31_RS13700	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EGA31_RS13700	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EGA31_RS13705	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EGA31_RS13710	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
EGA31_RS13725	COG4638	Rieske (2fe-2S)
EGA31_RS13775	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EGA31_RS13780	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EGA31_RS13795	COG1970	mechanosensitive ion channel activity
EGA31_RS13800	COG0521	Mo-molybdopterin cofactor biosynthetic process
EGA31_RS13800	COG0315	cyclic pyranopterin monophosphate synthase activity
EGA31_RS13805	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EGA31_RS13815	COG2205	protein histidine kinase activity
EGA31_RS13835	COG1960	acyl-CoA dehydrogenase activity
EGA31_RS13840	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EGA31_RS13865	COG1024	Enoyl-CoA hydratase
EGA31_RS13895	COG0138	bifunctional purine biosynthesis protein purh
EGA31_RS13940	COG4942	peptidase
EGA31_RS13960	COG0166	Belongs to the GPI family
EGA31_RS13970	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EGA31_RS14005	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EGA31_RS14025	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EGA31_RS14030	COG0246	Mannitol dehydrogenase
EGA31_RS14090	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGA31_RS14190	COG2801	Transposase and inactivated derivatives
EGA31_RS14190	COG3415	Transposase
EGA31_RS14195	COG3328	transposase activity
EGA31_RS14265	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EGA31_RS14275	COG0438	transferase activity, transferring glycosyl groups
EGA31_RS14285	COG0745	RESPONSE REGULATOR receiver
EGA31_RS14295	COG3547	Transposase (IS116 IS110 IS902 family)
EGA31_RS14315	COG0259	pyridoxamine-phosphate oxidase activity
EGA31_RS14340	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EGA31_RS14380	COG2814	Major facilitator Superfamily
EGA31_RS14395	COG0435	Glutathione S-transferase
EGA31_RS14405	COG1278	Cold shock
EGA31_RS14410	COG3304	Inner membrane component domain
EGA31_RS14435	COG0521	Mo-molybdopterin cofactor biosynthetic process
EGA31_RS14455	COG1061	Type III restriction enzyme res subunit
EGA31_RS14460	COG0183	Belongs to the thiolase family
EGA31_RS14475	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGA31_RS14500	COG1250	3-hydroxyacyl-CoA dehydrogenase
EGA31_RS14500	COG1024	Enoyl-CoA hydratase
EGA31_RS14505	COG0183	Belongs to the thiolase family
EGA31_RS14530	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EGA31_RS14540	COG3961	Belongs to the TPP enzyme family
EGA31_RS14555	COG0318	PFAM AMP-dependent synthetase and ligase
EGA31_RS14570	COG1024	Enoyl-CoA hydratase
EGA31_RS14580	COG1309	transcriptional regulator
EGA31_RS14610	COG1309	transcriptional regulator
EGA31_RS14640	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EGA31_RS14665	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EGA31_RS14670	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EGA31_RS14675	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EGA31_RS14720	COG1960	acyl-CoA dehydrogenase activity
EGA31_RS14730	COG0778	Nitroreductase
EGA31_RS14730	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
EGA31_RS14815	COG2124	cytochrome p450
EGA31_RS14835	COG2124	cytochrome p450
EGA31_RS14845	COG1309	transcriptional regulator
EGA31_RS14850	COG0183	Belongs to the thiolase family
EGA31_RS14870	COG4638	Rieske (2fe-2S)
EGA31_RS14880	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EGA31_RS14890	COG1960	acyl-CoA dehydrogenase activity
EGA31_RS14905	COG1960	acyl-CoA dehydrogenase activity
EGA31_RS14915	COG1028	Short-chain dehydrogenase reductase Sdr
EGA31_RS14925	COG1028	Short-chain dehydrogenase reductase Sdr
EGA31_RS14930	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EGA31_RS14970	COG2132	Multicopper oxidase
EGA31_RS14985	COG1028	Short-chain dehydrogenase reductase Sdr
EGA31_RS14995	COG1053	succinate dehydrogenase
EGA31_RS15000	COG3384	dioxygenase
EGA31_RS15005	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EGA31_RS15010	COG2267	carboxylic ester hydrolase activity
EGA31_RS15025	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGA31_RS15045	COG0277	FAD linked oxidase domain protein
EGA31_RS15095	COG1028	Short-chain dehydrogenase reductase Sdr
EGA31_RS15105	COG1028	Short-chain dehydrogenase reductase Sdr
EGA31_RS15115	COG1028	Short-chain dehydrogenase reductase Sdr
EGA31_RS15145	COG0567	Dehydrogenase, E1 component
EGA31_RS15145	COG0508	dehydrogenase complex catalyzes the overall conversion of
EGA31_RS15170	COG0039	L-malate dehydrogenase activity
EGA31_RS15175	COG0598	Magnesium transport protein CorA
EGA31_RS15220	COG2239	Acts as a magnesium transporter
EGA31_RS15240	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EGA31_RS15245	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EGA31_RS15250	COG5662	AntiSigma factor
EGA31_RS15265	COG1309	transcriptional regulator
EGA31_RS15315	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EGA31_RS15320	COG4208	sulfate ABC transporter
EGA31_RS15325	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EGA31_RS15330	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EGA31_RS15345	COG3387	PFAM Glycoside hydrolase 15-related
EGA31_RS15355	COG0481	GTPase activity
EGA31_RS15370	COG1234	tRNA 3'-trailer cleavage
EGA31_RS15375	COG1305	Transglutaminase-like
EGA31_RS15385	COG2308	Evidence 4 Homologs of previously reported genes of
EGA31_RS15400	COG2333	competence protein COMEC
EGA31_RS15400	COG0658	competence protein
EGA31_RS15405	COG1596	polysaccharide export
EGA31_RS15405	COG1555	photosystem II stabilization
EGA31_RS15410	COG1960	acyl-CoA dehydrogenase activity
EGA31_RS15415	COG1960	acyl-CoA dehydrogenase activity
EGA31_RS15440	COG5651	PPE family
EGA31_RS15445	COG0318	PFAM AMP-dependent synthetase and ligase
EGA31_RS15475	COG2755	lipolytic protein G-D-S-L family
EGA31_RS15485	COG0799	negative regulation of ribosome biogenesis
EGA31_RS15490	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EGA31_RS15500	COG0542	response to heat
EGA31_RS15505	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EGA31_RS15515	COG5002	protein histidine kinase activity
EGA31_RS15520	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EGA31_RS15525	COG2188	Transcriptional regulator
EGA31_RS15540	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EGA31_RS15545	COG0066	3-isopropylmalate dehydratase activity
EGA31_RS15580	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EGA31_RS15585	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EGA31_RS15600	COG1530	ribonuclease E activity
EGA31_RS15605	COG0105	UTP biosynthetic process
EGA31_RS15615	COG0285	dihydrofolate synthase activity
EGA31_RS15620	COG0525	valine-tRNA ligase activity
EGA31_RS15625	COG3268	Saccharopine dehydrogenase
EGA31_RS15630	COG1388	LysM domain
EGA31_RS15635	COG3328	transposase activity
EGA31_RS15640	COG0746	molybdenum cofactor guanylyltransferase activity
EGA31_RS15645	COG1013	pyruvate-flavodoxin oxidoreductase activity
EGA31_RS15650	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EGA31_RS15650	COG0674	pyruvate-flavodoxin oxidoreductase activity
EGA31_RS15665	COG0740	serine-type endopeptidase activity
EGA31_RS15670	COG0740	serine-type endopeptidase activity
EGA31_RS15690	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EGA31_RS15705	COG0698	ribose 5-phosphate isomerase
EGA31_RS15710	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EGA31_RS15735	COG2346	COG2346, Truncated hemoglobins
EGA31_RS15760	COG2902	Dehydrogenase
EGA31_RS15770	COG0629	single-stranded DNA binding
EGA31_RS15790	COG0657	acetylesterase activity
EGA31_RS15800	COG2801	Transposase and inactivated derivatives
EGA31_RS15800	COG3415	Transposase
EGA31_RS15830	COG0508	dehydrogenase complex catalyzes the overall conversion of
EGA31_RS15850	COG2030	dehydratase
EGA31_RS15855	COG1960	acyl-CoA dehydrogenase activity
EGA31_RS15865	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EGA31_RS15885	COG0300	oxidoreductase activity
EGA31_RS15890	COG0433	COG0433 Predicted ATPase
EGA31_RS15895	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
EGA31_RS15910	COG1376	ErfK ybiS ycfS ynhG family protein
EGA31_RS15920	COG2409	Drug exporters of the RND superfamily
EGA31_RS15955	COG0736	holo-[acyl-carrier-protein] synthase activity
EGA31_RS15970	COG3757	hydrolase, family 25
EGA31_RS16020	COG2124	cytochrome p450
EGA31_RS16050	COG1960	acyl-CoA dehydrogenase activity
EGA31_RS16055	COG1960	acyl-CoA dehydrogenase activity
EGA31_RS16060	COG1960	acyl-CoA dehydrogenase activity
EGA31_RS16065	COG1960	acyl-CoA dehydrogenase activity
EGA31_RS16095	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EGA31_RS16110	COG1960	acyl-CoA dehydrogenase activity
EGA31_RS16115	COG1960	acyl-CoA dehydrogenase activity
EGA31_RS16120	COG0657	acetylesterase activity
EGA31_RS16125	COG2124	cytochrome p450
EGA31_RS16145	COG1309	transcriptional regulator
EGA31_RS16160	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EGA31_RS16180	COG2072	flavoprotein involved in K transport
EGA31_RS16185	COG4638	Rieske (2fe-2S)
EGA31_RS16210	COG2124	cytochrome p450
EGA31_RS16220	COG0183	Belongs to the thiolase family
EGA31_RS16250	COG1024	Enoyl-CoA hydratase
EGA31_RS16265	COG1028	Short-chain dehydrogenase reductase Sdr
EGA31_RS16285	COG1024	Enoyl-CoA hydratase
EGA31_RS16290	COG1024	Enoyl-CoA hydratase
EGA31_RS16295	COG1024	Enoyl-CoA hydratase
EGA31_RS16320	COG1802	Transcriptional regulator
EGA31_RS16325	COG1960	acyl-CoA dehydrogenase activity
EGA31_RS16330	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EGA31_RS16335	COG0183	Belongs to the thiolase family
EGA31_RS16345	COG1960	acyl-CoA dehydrogenase activity
EGA31_RS16350	COG1028	Short-chain dehydrogenase reductase Sdr
EGA31_RS16410	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EGA31_RS16415	COG2123	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EGA31_RS16420	COG1234	tRNA 3'-trailer cleavage
EGA31_RS16425	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EGA31_RS16450	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EGA31_RS16460	COG0058	SHG alpha-glucan phosphorylase activity
EGA31_RS16470	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EGA31_RS16485	COG0346	lactoylglutathione lyase activity
EGA31_RS16510	COG2814	Major facilitator Superfamily
EGA31_RS16515	COG0583	DNA-binding transcription factor activity
EGA31_RS16535	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EGA31_RS16560	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EGA31_RS16580	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EGA31_RS16595	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EGA31_RS16595	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EGA31_RS16605	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EGA31_RS16610	COG0356	it plays a direct role in the translocation of protons across the membrane
EGA31_RS16630	COG2890	protein-(glutamine-N5) methyltransferase activity
EGA31_RS16635	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EGA31_RS16655	COG0083	homoserine kinase activity
EGA31_RS16665	COG0460	homoserine dehydrogenase
EGA31_RS16675	COG0018	arginyl-trna synthetase
EGA31_RS16720	COG0494	nUDIX hydrolase
EGA31_RS16725	COG3631	Ketosteroid isomerase-related protein
EGA31_RS16815	COG1403	HNH endonuclease
EGA31_RS16900	COG4585	Histidine kinase
EGA31_RS16910	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EGA31_RS16920	COG0183	Belongs to the thiolase family
EGA31_RS16925	COG3479	Phenolic acid decarboxylase
EGA31_RS16930	COG0596	Alpha beta hydrolase
EGA31_RS16940	COG1960	acyl-CoA dehydrogenase activity
EGA31_RS16945	COG1960	acyl-CoA dehydrogenase activity
EGA31_RS16955	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EGA31_RS16970	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EGA31_RS16975	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGA31_RS16980	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EGA31_RS16985	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EGA31_RS16985	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EGA31_RS17015	COG2124	cytochrome p450
EGA31_RS17030	COG1028	Short-chain dehydrogenase reductase Sdr
EGA31_RS17055	COG3415	Transposase
EGA31_RS17055	COG2801	Transposase and inactivated derivatives
EGA31_RS17065	COG0590	tRNA wobble adenosine to inosine editing
EGA31_RS17070	COG0640	Transcriptional regulator
EGA31_RS17115	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EGA31_RS17135	COG0454	-acetyltransferase
EGA31_RS17135	COG0456	acetyltransferase
EGA31_RS17140	COG0745	RESPONSE REGULATOR receiver
EGA31_RS17150	COG3118	belongs to the thioredoxin family
EGA31_RS17170	COG4044	May play a role in the intracellular transport of hydrophobic ligands
EGA31_RS17180	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EGA31_RS17190	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EGA31_RS17210	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EGA31_RS17230	COG2837	iron assimilation
EGA31_RS17255	COG0047	phosphoribosylformylglycinamidine synthase activity
EGA31_RS17260	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EGA31_RS17270	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EGA31_RS17285	COG0477	Major facilitator Superfamily
EGA31_RS17290	COG0477	Major facilitator Superfamily
EGA31_RS17310	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EGA31_RS17325	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EGA31_RS17385	COG4221	oxidoreductase activity
EGA31_RS17390	COG2124	cytochrome p450
EGA31_RS17420	COG2205	protein histidine kinase activity
EGA31_RS17425	COG0745	RESPONSE REGULATOR receiver
EGA31_RS17440	COG2801	Transposase and inactivated derivatives
EGA31_RS17440	COG3415	Transposase
EGA31_RS17490	COG1316	TRANSCRIPTIONal
EGA31_RS17505	COG1024	Enoyl-CoA hydratase
EGA31_RS17510	COG0390	transport system, permease component
EGA31_RS17515	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EGA31_RS17525	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
EGA31_RS17550	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EGA31_RS17575	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EGA31_RS17585	COG1028	Short-chain dehydrogenase reductase Sdr
EGA31_RS17595	COG1960	acyl-CoA dehydrogenase activity
EGA31_RS17600	COG1960	acyl-CoA dehydrogenase activity
EGA31_RS17605	COG0318	PFAM AMP-dependent synthetase and ligase
EGA31_RS17620	COG0028	Belongs to the TPP enzyme family
EGA31_RS17630	COG3001	Fructosamine kinase
EGA31_RS17640	COG1024	Enoyl-CoA hydratase
EGA31_RS17650	COG2124	cytochrome p450
EGA31_RS17660	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGA31_RS17675	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EGA31_RS17690	COG4638	Rieske (2fe-2S)
EGA31_RS17720	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EGA31_RS17725	COG4569	acetaldehyde dehydrogenase (acetylating) activity
EGA31_RS17730	COG3971	2-oxopent-4-enoate hydratase activity
EGA31_RS17735	COG1053	succinate dehydrogenase
EGA31_RS17740	COG2030	dehydratase
EGA31_RS17760	COG2030	dehydratase
EGA31_RS17765	COG1960	acyl-CoA dehydrogenase activity
EGA31_RS17770	COG1960	acyl-CoA dehydrogenase activity
EGA31_RS17775	COG2124	cytochrome p450
EGA31_RS17780	COG0183	Belongs to the thiolase family
EGA31_RS17795	COG1028	Short-chain dehydrogenase reductase Sdr
EGA31_RS17800	COG1028	Short-chain dehydrogenase reductase Sdr
EGA31_RS17805	COG1024	Enoyl-CoA hydratase
EGA31_RS17835	COG0183	Belongs to the thiolase family
EGA31_RS17845	COG1028	Short-chain dehydrogenase reductase Sdr
EGA31_RS17850	COG1960	acyl-CoA dehydrogenase activity
EGA31_RS17855	COG0318	PFAM AMP-dependent synthetase and ligase
EGA31_RS17860	COG1960	acyl-CoA dehydrogenase activity
EGA31_RS17865	COG1960	acyl-CoA dehydrogenase activity
EGA31_RS17870	COG1960	acyl-CoA dehydrogenase activity
EGA31_RS17875	COG0436	Aminotransferase
EGA31_RS17925	COG1960	acyl-CoA dehydrogenase activity
EGA31_RS17930	COG1309	transcriptional regulator
EGA31_RS17935	COG1609	Transcriptional regulator
EGA31_RS17945	COG1121	(ABC) transporter
EGA31_RS17950	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EGA31_RS17955	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EGA31_RS17975	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EGA31_RS17990	COG0215	cysteine-tRNA ligase activity
EGA31_RS18000	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EGA31_RS18020	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
EGA31_RS18100	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EGA31_RS18130	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EGA31_RS18135	COG0302	gtp cyclohydrolase
EGA31_RS18140	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EGA31_RS18155	COG2267	carboxylic ester hydrolase activity
EGA31_RS18165	COG1063	alcohol dehydrogenase
EGA31_RS18170	COG1403	HNH endonuclease
EGA31_RS18180	COG3391	amine dehydrogenase activity
EGA31_RS18195	COG0037	tRNA processing
EGA31_RS18205	COG2027	D-alanyl-D-alanine carboxypeptidase
EGA31_RS18225	COG1215	transferase activity, transferring glycosyl groups
EGA31_RS18245	COG3415	Transposase
EGA31_RS18245	COG2801	Transposase and inactivated derivatives
EGA31_RS18255	COG0470	DNA polymerase III
EGA31_RS18280	COG1111	helicase
EGA31_RS18280	COG1205	dead DEAH box helicase
EGA31_RS18350	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EGA31_RS18355	COG0601	transmembrane transport
EGA31_RS18370	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EGA31_RS18405	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EGA31_RS18420	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EGA31_RS18455	COG1408	metallophosphoesterase
EGA31_RS18460	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EGA31_RS18520	COG1366	Belongs to the anti-sigma-factor antagonist family
EGA31_RS18525	COG1366	Belongs to the anti-sigma-factor antagonist family
EGA31_RS18530	COG2172	sigma factor antagonist activity
EGA31_RS18555	COG2890	protein-(glutamine-N5) methyltransferase activity
EGA31_RS18560	COG0693	protein deglycase activity
EGA31_RS18565	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGA31_RS18575	COG0437	4 iron, 4 sulfur cluster binding
EGA31_RS18580	COG3383	formate dehydrogenase (NAD+) activity
EGA31_RS18580	COG0243	molybdopterin cofactor binding
EGA31_RS18585	COG0243	molybdopterin cofactor binding
EGA31_RS18585	COG3383	formate dehydrogenase (NAD+) activity
EGA31_RS18590	COG0709	Synthesizes selenophosphate from selenide and ATP
EGA31_RS18630	COG0714	Associated with various cellular activities
EGA31_RS18655	COG1695	Transcriptional regulator
EGA31_RS18660	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EGA31_RS18675	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EGA31_RS18685	COG0121	glutamine amidotransferase
EGA31_RS18735	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EGA31_RS18740	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EGA31_RS18755	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EGA31_RS18760	COG0860	N-Acetylmuramoyl-L-alanine amidase
EGA31_RS18775	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EGA31_RS18785	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EGA31_RS18840	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EGA31_RS18875	COG1357	PFAM Pentapeptide repeats (8 copies)
EGA31_RS18890	COG2018	Roadblock/LC7 domain
EGA31_RS18895	COG5002	protein histidine kinase activity
EGA31_RS18905	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EGA31_RS18915	COG0587	DNA-directed DNA polymerase activity
EGA31_RS18920	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EGA31_RS18925	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EGA31_RS18925	COG1877	trehalose-phosphatase activity
EGA31_RS18930	COG2030	dehydratase
EGA31_RS18975	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EGA31_RS18995	COG3537	Alpha-1,2-mannosidase
EGA31_RS19005	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EGA31_RS19035	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EGA31_RS19040	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EGA31_RS19065	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EGA31_RS19080	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EGA31_RS19090	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
EGA31_RS19115	COG1752	Esterase of the alpha-beta hydrolase superfamily
EGA31_RS19125	COG0243	molybdopterin cofactor binding
EGA31_RS19140	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EGA31_RS19165	COG2030	dehydratase
EGA31_RS19170	COG2030	dehydratase
EGA31_RS19175	COG2030	dehydratase
EGA31_RS19185	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EGA31_RS19205	COG4941	Belongs to the sigma-70 factor family
EGA31_RS19215	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EGA31_RS19220	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EGA31_RS19225	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EGA31_RS19235	COG2318	DinB family
EGA31_RS19265	COG0222	ribosome binding
EGA31_RS19290	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EGA31_RS19300	COG1960	acyl-CoA dehydrogenase activity
EGA31_RS19330	COG1309	transcriptional regulator
EGA31_RS19365	COG1028	Short-chain dehydrogenase reductase Sdr
EGA31_RS19375	COG0483	inositol monophosphate 1-phosphatase activity
EGA31_RS19400	COG0535	radical SAM domain protein
EGA31_RS19445	COG0088	Forms part of the polypeptide exit tunnel
EGA31_RS19470	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EGA31_RS19485	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EGA31_RS19505	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EGA31_RS19550	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EGA31_RS19555	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EGA31_RS19570	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGA31_RS19580	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EGA31_RS19585	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EGA31_RS19600	COG1063	alcohol dehydrogenase
EGA31_RS19610	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EGA31_RS19625	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EGA31_RS19635	COG0563	adenylate kinase activity
EGA31_RS19655	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EGA31_RS19670	COG0577	efflux transmembrane transporter activity
EGA31_RS19675	COG0577	efflux transmembrane transporter activity
EGA31_RS19675	COG1136	(ABC) transporter
EGA31_RS19690	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EGA31_RS19695	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EGA31_RS19710	COG1960	acyl-CoA dehydrogenase activity
EGA31_RS19735	COG3794	PFAM blue (type 1) copper domain protein
EGA31_RS19785	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EGA31_RS19790	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EGA31_RS19820	COG0101	tRNA pseudouridine synthase activity
EGA31_RS19840	COG1404	Belongs to the peptidase S8 family
EGA31_RS19850	COG1674	ftsk spoiiie
EGA31_RS19860	COG4842	Belongs to the WXG100 family
EGA31_RS19865	COG4842	Belongs to the WXG100 family
EGA31_RS19875	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EGA31_RS19880	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EGA31_RS19895	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGA31_RS19910	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EGA31_RS19930	COG0076	glutamate decarboxylase activity
EGA31_RS19955	COG0456	acetyltransferase
EGA31_RS19970	COG0459	protein refolding
EGA31_RS19985	COG1396	sequence-specific DNA binding
EGA31_RS19990	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
EGA31_RS20005	COG1914	H( )-stimulated, divalent metal cation uptake system
EGA31_RS20010	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EGA31_RS20030	COG2072	flavoprotein involved in K transport
EGA31_RS20040	COG0659	secondary active sulfate transmembrane transporter activity
EGA31_RS20050	COG0501	Belongs to the peptidase M48B family
EGA31_RS20055	COG0142	geranyltranstransferase activity
EGA31_RS20070	COG2226	methyltransferase
EGA31_RS20100	COG4948	Mandelate Racemase Muconate Lactonizing
EGA31_RS20105	COG1228	amidohydrolase
EGA31_RS20110	COG0318	PFAM AMP-dependent synthetase and ligase
EGA31_RS20120	COG0667	Aldo Keto reductase
EGA31_RS20135	COG4221	oxidoreductase activity
EGA31_RS20145	COG0306	phosphate transporter
EGA31_RS20190	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EGA31_RS20195	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EGA31_RS20205	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EGA31_RS20220	COG2894	cell division
EGA31_RS20225	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EGA31_RS20235	COG0785	Cytochrome C biogenesis protein
EGA31_RS20245	COG0406	alpha-ribazole phosphatase activity
EGA31_RS20250	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EGA31_RS20265	COG4948	Mandelate Racemase Muconate Lactonizing
EGA31_RS20270	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EGA31_RS20280	COG0477	Major facilitator Superfamily
EGA31_RS20285	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGA31_RS20305	COG2755	lipolytic protein G-D-S-L family
EGA31_RS20315	COG1366	Belongs to the anti-sigma-factor antagonist family
EGA31_RS20340	COG0181	hydroxymethylbilane synthase activity
EGA31_RS20395	COG2030	dehydratase
EGA31_RS20475	COG0588	phosphoglycerate mutase activity
EGA31_RS20485	COG0438	transferase activity, transferring glycosyl groups
EGA31_RS20510	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EGA31_RS20530	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EGA31_RS20560	COG2733	membrane
EGA31_RS20575	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EGA31_RS20635	COG1505	serine-type exopeptidase activity
EGA31_RS20645	COG1024	Enoyl-CoA hydratase
EGA31_RS20725	COG4221	oxidoreductase activity
EGA31_RS20735	COG0738	Major facilitator superfamily
EGA31_RS20740	COG0688	phosphatidylethanolamine metabolic process
EGA31_RS20750	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EGA31_RS20785	COG2032	superoxide dismutase activity
EGA31_RS20800	COG0242	peptide deformylase activity
EGA31_RS20830	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EGA31_RS20850	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGA31_RS20860	COG2234	aminopeptidase activity
EGA31_RS20865	COG2234	aminopeptidase activity
EGA31_RS20895	COG2022	thiamine diphosphate biosynthetic process
EGA31_RS20905	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EGA31_RS20905	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
EGA31_RS20910	COG0352	thiamine-phosphate diphosphorylase activity
EGA31_RS20925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EGA31_RS20940	COG1309	transcriptional regulator
EGA31_RS20965	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EGA31_RS20980	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EGA31_RS20990	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EGA31_RS21000	COG1028	Short-chain dehydrogenase reductase Sdr
EGA31_RS21005	COG1960	acyl-CoA dehydrogenase activity
EGA31_RS21010	COG1960	acyl-CoA dehydrogenase activity
EGA31_RS21045	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EGA31_RS21065	COG0406	alpha-ribazole phosphatase activity
EGA31_RS21075	COG1994	Peptidase M50
EGA31_RS21135	COG2826	transposase and inactivated derivatives, IS30 family
EGA31_RS21140	COG0542	response to heat
EGA31_RS21200	COG0789	Transcriptional regulator
EGA31_RS21205	COG0484	heat shock protein binding
EGA31_RS21210	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EGA31_RS21245	COG2814	Major facilitator Superfamily
EGA31_RS21260	COG0247	lactate metabolic process
EGA31_RS21260	COG2181	nitrate reductase activity
EGA31_RS21290	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EGA31_RS21330	COG2124	cytochrome p450
EGA31_RS21370	COG1376	ErfK ybiS ycfS ynhG family protein
EGA31_RS21390	COG0246	Mannitol dehydrogenase
EGA31_RS21425	COG2130	NADP-dependent
EGA31_RS21490	COG0778	Nitroreductase
EGA31_RS21495	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EGA31_RS21515	COG1404	Belongs to the peptidase S8 family
EGA31_RS21570	COG0803	Belongs to the bacterial solute-binding protein 9 family
EGA31_RS21575	COG1121	(ABC) transporter
EGA31_RS21580	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EGA31_RS21590	COG0523	cobalamin synthesis protein
EGA31_RS21600	COG0254	rRNA binding
EGA31_RS21615	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EGA31_RS21620	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EGA31_RS21625	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EGA31_RS21635	COG0701	Predicted permease
EGA31_RS21655	COG1819	glycosyl
EGA31_RS21670	COG3328	transposase activity
EGA31_RS21710	COG0318	PFAM AMP-dependent synthetase and ligase
EGA31_RS21730	COG3547	Transposase (IS116 IS110 IS902 family)
EGA31_RS21740	COG1937	Protein conserved in bacteria
EGA31_RS21760	COG2226	methyltransferase
EGA31_RS21760	COG3433	isochorismatase activity
EGA31_RS21760	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EGA31_RS21765	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EGA31_RS21765	COG3433	isochorismatase activity
EGA31_RS21765	COG2226	methyltransferase
EGA31_RS21770	COG0477	Major facilitator Superfamily
EGA31_RS21785	COG2375	cellular response to nickel ion
EGA31_RS21785	COG1132	(ABC) transporter
EGA31_RS21805	COG1129	ABC transporter
EGA31_RS21825	COG1120	ATPase activity
EGA31_RS21830	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EGA31_RS21870	COG0346	lactoylglutathione lyase activity
EGA31_RS21885	COG1960	acyl-CoA dehydrogenase activity
EGA31_RS21900	COG0318	PFAM AMP-dependent synthetase and ligase
EGA31_RS21910	COG2223	nitrite transmembrane transporter activity
EGA31_RS21915	COG1309	transcriptional regulator
EGA31_RS21925	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EGA31_RS21930	COG1984	allophanate hydrolase subunit 2
EGA31_RS21960	COG2146	nitrite reductase [NAD(P)H] activity
EGA31_RS21965	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EGA31_RS21965	COG2146	nitrite reductase [NAD(P)H] activity
EGA31_RS21985	COG1053	succinate dehydrogenase
EGA31_RS22005	COG1960	acyl-CoA dehydrogenase activity
EGA31_RS22010	COG0183	Belongs to the thiolase family
EGA31_RS22015	COG1028	Short-chain dehydrogenase reductase Sdr
EGA31_RS22020	COG2030	dehydratase
EGA31_RS22035	COG1472	Belongs to the glycosyl hydrolase 3 family
EGA31_RS22050	COG4981	capsule polysaccharide biosynthetic process
EGA31_RS22100	COG0583	DNA-binding transcription factor activity
EGA31_RS22105	COG0028	Belongs to the TPP enzyme family
EGA31_RS22110	COG1012	belongs to the aldehyde dehydrogenase family
EGA31_RS22115	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EGA31_RS22125	COG2801	Transposase and inactivated derivatives
EGA31_RS22125	COG3415	Transposase
EGA31_RS22160	COG0500	methyltransferase
EGA31_RS22170	COG1309	transcriptional regulator
EGA31_RS22185	COG1024	Enoyl-CoA hydratase
EGA31_RS22195	COG0657	acetylesterase activity
EGA31_RS22200	COG0657	acetylesterase activity
EGA31_RS22240	COG2203	Gaf domain
EGA31_RS22240	COG2199	diguanylate cyclase activity
EGA31_RS22245	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
EGA31_RS22260	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EGA31_RS22270	COG2409	Drug exporters of the RND superfamily
EGA31_RS22295	COG0243	molybdopterin cofactor binding
EGA31_RS22305	COG1376	ErfK ybiS ycfS ynhG family protein
EGA31_RS22310	COG2814	Major facilitator Superfamily
EGA31_RS22315	COG1937	Protein conserved in bacteria
EGA31_RS22320	COG0129	dihydroxy-acid dehydratase activity
EGA31_RS22335	COG4122	O-methyltransferase activity
EGA31_RS22345	COG1472	Belongs to the glycosyl hydrolase 3 family
EGA31_RS22365	COG2267	carboxylic ester hydrolase activity
EGA31_RS22405	COG3619	membrane
EGA31_RS22420	COG1714	RDD family
EGA31_RS22435	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EGA31_RS22460	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EGA31_RS22465	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EGA31_RS22495	COG0657	acetylesterase activity
EGA31_RS22500	COG2072	flavoprotein involved in K transport
EGA31_RS22520	COG2124	cytochrome p450
EGA31_RS22545	COG1960	acyl-CoA dehydrogenase activity
EGA31_RS22595	COG1309	transcriptional regulator
EGA31_RS22635	COG1028	Short-chain dehydrogenase reductase Sdr
EGA31_RS22640	COG1012	belongs to the aldehyde dehydrogenase family
EGA31_RS22655	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EGA31_RS22665	COG1741	Belongs to the pirin family
EGA31_RS22670	COG0783	Belongs to the Dps family
EGA31_RS22700	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EGA31_RS22765	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGA31_RS22785	COG2267	carboxylic ester hydrolase activity
EGA31_RS22795	COG1937	Protein conserved in bacteria
EGA31_RS22810	COG0842	Transport permease protein
EGA31_RS22810	COG1129	ABC transporter
EGA31_RS22830	COG3281	Trehalose synthase
EGA31_RS22840	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EGA31_RS22860	COG0028	Belongs to the TPP enzyme family
EGA31_RS22865	COG0583	DNA-binding transcription factor activity
EGA31_RS22885	COG3321	synthase
EGA31_RS22885	COG0604	alcohol dehydrogenase
EGA31_RS22905	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EGA31_RS22905	COG2755	lipolytic protein G-D-S-L family
EGA31_RS22920	COG0028	Belongs to the TPP enzyme family
EGA31_RS22935	COG2072	flavoprotein involved in K transport
EGA31_RS22945	COG1028	Short-chain dehydrogenase reductase Sdr
EGA31_RS22960	COG0318	PFAM AMP-dependent synthetase and ligase
EGA31_RS22965	COG1028	Short-chain dehydrogenase reductase Sdr
EGA31_RS23000	COG0318	PFAM AMP-dependent synthetase and ligase
EGA31_RS23030	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
EGA31_RS23045	COG0596	Alpha beta hydrolase
EGA31_RS23050	COG2226	methyltransferase
EGA31_RS23085	COG1063	alcohol dehydrogenase
EGA31_RS23105	COG1028	Short-chain dehydrogenase reductase Sdr
EGA31_RS23110	COG2072	flavoprotein involved in K transport
EGA31_RS23140	COG1028	Short-chain dehydrogenase reductase Sdr
EGA31_RS23185	COG1309	transcriptional regulator
EGA31_RS23190	COG0596	Alpha beta hydrolase
EGA31_RS23195	COG1028	Short-chain dehydrogenase reductase Sdr
EGA31_RS23200	COG0318	PFAM AMP-dependent synthetase and ligase
EGA31_RS23235	COG1609	Transcriptional regulator
EGA31_RS23255	COG1309	transcriptional regulator
EGA31_RS23275	COG3588	fructose-bisphosphate aldolase
EGA31_RS23305	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
EGA31_RS23310	COG4638	Rieske (2fe-2S)
EGA31_RS23320	COG2197	response regulator
EGA31_RS23340	COG1674	ftsk spoiiie
EGA31_RS23435	COG1595	DNA-templated transcription, initiation
EGA31_RS23455	COG0860	N-Acetylmuramoyl-L-alanine amidase
EGA31_RS23455	COG3409	Peptidoglycan-binding domain 1 protein
EGA31_RS23470	COG1192	Involved in chromosome partitioning
EGA31_RS23475	COG0357	Ribosomal RNA small subunit methyltransferase G
EGA31_RS23485	COG0706	membrane insertase activity
EGA31_RS23490	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EGA31_RS23495	COG0594	ribonuclease P activity