locus-tag	class	description
LH58_RS00090	COG0515	serine threonine protein kinase
LH58_RS00115	COG1716	ATPase activity
LH58_RS00185	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LH58_RS00240	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LH58_RS00245	COG0596	Alpha beta hydrolase
LH58_RS00245	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LH58_RS00270	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LH58_RS00340	COG0277	FAD linked oxidase domain protein
LH58_RS00365	COG1309	transcriptional regulator
LH58_RS00370	COG1028	Short-chain dehydrogenase reductase Sdr
LH58_RS00385	COG3344	reverse transcriptase
LH58_RS00400	COG1228	amidohydrolase
LH58_RS00420	COG1309	transcriptional regulator
LH58_RS00450	COG3260	NADH ubiquinone oxidoreductase 20
LH58_RS00460	COG0650	Formate hydrogenlyase subunit 4
LH58_RS00470	COG0651	ATP synthesis coupled electron transport
LH58_RS00475	COG3261	NADH dehydrogenase
LH58_RS00475	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
LH58_RS00545	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LH58_RS00585	COG0657	acetylesterase activity
LH58_RS00595	COG2755	lipolytic protein G-D-S-L family
LH58_RS00595	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
LH58_RS00625	COG1376	ErfK ybiS ycfS ynhG family protein
LH58_RS00630	COG0583	DNA-binding transcription factor activity
LH58_RS00635	COG0028	Belongs to the TPP enzyme family
LH58_RS00680	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LH58_RS00715	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LH58_RS00770	COG0038	chloride channel
LH58_RS00775	COG1309	transcriptional regulator
LH58_RS00790	COG1012	belongs to the aldehyde dehydrogenase family
LH58_RS00795	COG1028	Short-chain dehydrogenase reductase Sdr
LH58_RS00800	COG0604	alcohol dehydrogenase
LH58_RS00800	COG1028	Short-chain dehydrogenase reductase Sdr
LH58_RS00800	COG3321	synthase
LH58_RS00825	COG2365	Tyrosine phosphatase family
LH58_RS00860	COG1309	transcriptional regulator
LH58_RS00865	COG0657	acetylesterase activity
LH58_RS00865	COG5651	PPE family
LH58_RS00870	COG5651	PPE family
LH58_RS00870	COG0657	acetylesterase activity
LH58_RS00875	COG0277	FAD linked oxidase domain protein
LH58_RS00880	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
LH58_RS00895	COG1802	Transcriptional regulator
LH58_RS00905	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LH58_RS00910	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LH58_RS00935	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LH58_RS00985	COG2267	carboxylic ester hydrolase activity
LH58_RS01000	COG1472	Belongs to the glycosyl hydrolase 3 family
LH58_RS01010	COG4122	O-methyltransferase activity
LH58_RS01025	COG1937	Protein conserved in bacteria
LH58_RS01030	COG2814	Major facilitator Superfamily
LH58_RS01035	COG1376	ErfK ybiS ycfS ynhG family protein
LH58_RS01060	COG0243	molybdopterin cofactor binding
LH58_RS01065	COG3590	peptidase
LH58_RS01105	COG2409	Drug exporters of the RND superfamily
LH58_RS01160	COG0657	acetylesterase activity
LH58_RS01165	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LH58_RS01175	COG0657	acetylesterase activity
LH58_RS01200	COG0297	glycogen (starch) synthase activity
LH58_RS01220	COG1487	ribonuclease activity
LH58_RS01260	COG4981	capsule polysaccharide biosynthetic process
LH58_RS01290	COG2030	dehydratase
LH58_RS01300	COG0183	Belongs to the thiolase family
LH58_RS01305	COG1960	acyl-CoA dehydrogenase activity
LH58_RS01325	COG1053	succinate dehydrogenase
LH58_RS01345	COG2146	nitrite reductase [NAD(P)H] activity
LH58_RS01345	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LH58_RS01400	COG1984	allophanate hydrolase subunit 2
LH58_RS01420	COG2223	nitrite transmembrane transporter activity
LH58_RS01425	COG2161	toxin-antitoxin pair type II binding
LH58_RS01435	COG0318	PFAM AMP-dependent synthetase and ligase
LH58_RS01440	COG1960	acyl-CoA dehydrogenase activity
LH58_RS01455	COG0346	lactoylglutathione lyase activity
LH58_RS01555	COG1404	Belongs to the peptidase S8 family
LH58_RS01580	COG1368	sulfuric ester hydrolase activity
LH58_RS01630	COG0778	Nitroreductase
LH58_RS01640	COG0671	phosphoesterase, PA-phosphatase related
LH58_RS01715	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LH58_RS01720	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LH58_RS01730	COG2226	methyltransferase
LH58_RS01745	COG2226	methyltransferase
LH58_RS01755	COG1252	NADH dehydrogenase
LH58_RS01790	COG2181	nitrate reductase activity
LH58_RS01790	COG0247	lactate metabolic process
LH58_RS01865	COG0789	Transcriptional regulator
LH58_RS01870	COG5263	repeat protein
LH58_RS01870	COG5651	PPE family
LH58_RS01890	COG1994	Peptidase M50
LH58_RS01905	COG2239	Acts as a magnesium transporter
LH58_RS01950	COG0746	molybdenum cofactor guanylyltransferase activity
LH58_RS01990	COG3360	Dodecin
LH58_RS02035	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
LH58_RS02050	COG1252	NADH dehydrogenase
LH58_RS02055	COG1403	HNH endonuclease
LH58_RS02095	COG1960	acyl-CoA dehydrogenase activity
LH58_RS02125	COG3321	synthase
LH58_RS02125	COG3321	synthase
LH58_RS02125	COG0604	alcohol dehydrogenase
LH58_RS02125	COG0604	alcohol dehydrogenase
LH58_RS02130	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LH58_RS02155	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LH58_RS02190	COG2234	aminopeptidase activity
LH58_RS02225	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LH58_RS02280	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LH58_RS02300	COG1028	Short-chain dehydrogenase reductase Sdr
LH58_RS02340	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LH58_RS02385	COG1024	Enoyl-CoA hydratase
LH58_RS02390	COG2337	Toxic component of a toxin-antitoxin (TA) module
LH58_RS02400	COG1505	serine-type exopeptidase activity
LH58_RS02460	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LH58_RS02485	COG2733	membrane
LH58_RS02690	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LH58_RS02690	COG1648	precorrin-2 dehydrogenase activity
LH58_RS02715	COG1366	Belongs to the anti-sigma-factor antagonist family
LH58_RS02720	COG2755	lipolytic protein G-D-S-L family
LH58_RS02720	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
LH58_RS02725	COG2755	lipolytic protein G-D-S-L family
LH58_RS02745	COG1113	amino acid transport
LH58_RS02760	COG0406	alpha-ribazole phosphatase activity
LH58_RS02770	COG0785	Cytochrome C biogenesis protein
LH58_RS02780	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LH58_RS02815	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
LH58_RS02820	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LH58_RS02875	COG4221	oxidoreductase activity
LH58_RS02895	COG0318	PFAM AMP-dependent synthetase and ligase
LH58_RS02900	COG1228	amidohydrolase
LH58_RS02950	COG0142	geranyltranstransferase activity
LH58_RS02965	COG2072	flavoprotein involved in K transport
LH58_RS02980	COG2345	Transcriptional regulator
LH58_RS02995	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LH58_RS03060	COG2402	Toxic component of a toxin-antitoxin (TA) module. An RNase
LH58_RS03070	COG3537	Alpha-1,2-mannosidase
LH58_RS03090	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LH58_RS03125	COG1487	ribonuclease activity
LH58_RS03145	COG2002	toxin-antitoxin pair type II binding
LH58_RS03155	COG2972	Histidine kinase
LH58_RS03160	COG0745	RESPONSE REGULATOR receiver
LH58_RS03225	COG0653	protein targeting
LH58_RS03300	COG1487	ribonuclease activity
LH58_RS03320	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
LH58_RS03365	COG2030	dehydratase
LH58_RS03405	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LH58_RS03415	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LH58_RS03455	COG1309	transcriptional regulator
LH58_RS03530	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LH58_RS03555	COG1960	acyl-CoA dehydrogenase activity
LH58_RS03570	COG1024	Enoyl-CoA hydratase
LH58_RS03585	COG1510	regulation of RNA biosynthetic process
LH58_RS03600	COG1309	transcriptional regulator
LH58_RS03660	COG0535	radical SAM domain protein
LH58_RS03770	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LH58_RS03830	COG0616	signal peptide processing
LH58_RS03845	COG0235	Class ii aldolase
LH58_RS03855	COG1070	Carbohydrate kinase
LH58_RS03920	COG0657	acetylesterase activity
LH58_RS03995	COG0406	alpha-ribazole phosphatase activity
LH58_RS04020	COG0745	RESPONSE REGULATOR receiver
LH58_RS04025	COG2205	protein histidine kinase activity
LH58_RS04060	COG1028	Short-chain dehydrogenase reductase Sdr
LH58_RS04120	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LH58_RS04150	COG0477	Major facilitator Superfamily
LH58_RS04160	COG3573	Dehydrogenase
LH58_RS04180	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LH58_RS04200	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LH58_RS04205	COG2188	Transcriptional regulator
LH58_RS04210	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
LH58_RS04225	COG3547	Transposase (IS116 IS110 IS902 family)
LH58_RS04235	COG2837	iron assimilation
LH58_RS04285	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LH58_RS04335	COG0745	RESPONSE REGULATOR receiver
LH58_RS04380	COG0640	Transcriptional regulator
LH58_RS04385	COG0590	tRNA wobble adenosine to inosine editing
LH58_RS04425	COG3391	amine dehydrogenase activity
LH58_RS04465	COG4106	trans-aconitate 2-methyltransferase activity
LH58_RS04470	COG0596	Alpha beta hydrolase
LH58_RS04485	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LH58_RS04495	COG4585	Histidine kinase
LH58_RS04500	COG2132	Multicopper oxidase
LH58_RS04510	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LH58_RS04545	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LH58_RS04565	COG0183	Belongs to the thiolase family
LH58_RS04570	COG1250	3-hydroxyacyl-CoA dehydrogenase
LH58_RS04570	COG1024	Enoyl-CoA hydratase
LH58_RS04595	COG0521	Mo-molybdopterin cofactor biosynthetic process
LH58_RS04620	COG3304	Inner membrane component domain
LH58_RS04625	COG1278	Cold shock
LH58_RS04850	COG0183	Belongs to the thiolase family
LH58_RS04890	COG3328	transposase activity
LH58_RS05015	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LH58_RS05050	COG0739	heme binding
LH58_RS05160	COG1024	Enoyl-CoA hydratase
LH58_RS05175	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LH58_RS05195	COG0657	acetylesterase activity
LH58_RS05200	COG3391	amine dehydrogenase activity
LH58_RS05215	COG3391	amine dehydrogenase activity
LH58_RS05230	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LH58_RS05235	COG0521	Mo-molybdopterin cofactor biosynthetic process
LH58_RS05235	COG0315	cyclic pyranopterin monophosphate synthase activity
LH58_RS05240	COG1970	mechanosensitive ion channel activity
LH58_RS05260	COG0142	geranyltranstransferase activity
LH58_RS05275	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LH58_RS05280	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LH58_RS05315	COG4106	trans-aconitate 2-methyltransferase activity
LH58_RS05320	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LH58_RS05320	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LH58_RS05355	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LH58_RS05370	COG0084	hydrolase, TatD family'
LH58_RS05395	COG0318	PFAM AMP-dependent synthetase and ligase
LH58_RS05440	COG3956	TIGRFAM MazG family protein
LH58_RS05505	COG2205	protein histidine kinase activity
LH58_RS05510	COG0745	RESPONSE REGULATOR receiver
LH58_RS05545	COG0657	acetylesterase activity
LH58_RS05565	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LH58_RS05585	COG3328	transposase activity
LH58_RS05605	COG1028	Short-chain dehydrogenase reductase Sdr
LH58_RS05655	COG3391	amine dehydrogenase activity
LH58_RS05660	COG0318	PFAM AMP-dependent synthetase and ligase
LH58_RS05740	COG0183	Belongs to the thiolase family
LH58_RS05745	COG2755	lipolytic protein G-D-S-L family
LH58_RS05750	COG0657	acetylesterase activity
LH58_RS05790	COG1331	Highly conserved protein containing a thioredoxin domain
LH58_RS05860	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
LH58_RS05905	COG2272	Belongs to the type-B carboxylesterase lipase family
LH58_RS05945	COG0012	GTP binding
LH58_RS06000	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
LH58_RS06010	COG0596	Alpha beta hydrolase
LH58_RS06025	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LH58_RS06025	COG0574	Belongs to the PEP-utilizing enzyme family
LH58_RS06030	COG1403	HNH endonuclease
LH58_RS06035	COG3800	Transcriptional regulator
LH58_RS06035	COG1396	sequence-specific DNA binding
LH58_RS06070	COG0183	Belongs to the thiolase family
LH58_RS06090	COG1755	Isoprenylcysteine carboxyl methyltransferase
LH58_RS06100	COG1024	Enoyl-CoA hydratase
LH58_RS06105	COG1024	Enoyl-CoA hydratase
LH58_RS06110	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LH58_RS06120	COG2409	Drug exporters of the RND superfamily
LH58_RS06165	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
LH58_RS06175	COG3467	pyridoxamine 5'-phosphate
LH58_RS06220	COG1140	nitrate reductase beta subunit
LH58_RS06235	COG1217	gtp-binding protein TYPA
LH58_RS06290	COG0446	pyridine nucleotide-disulphide oxidoreductase
LH58_RS06290	COG1902	pentaerythritol trinitrate reductase activity
LH58_RS06300	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
LH58_RS06315	COG0604	alcohol dehydrogenase
LH58_RS06315	COG1028	Short-chain dehydrogenase reductase Sdr
LH58_RS06315	COG3321	synthase
LH58_RS06330	COG5651	PPE family
LH58_RS06340	COG2508	Transcriptional regulator
LH58_RS06340	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
LH58_RS06345	COG1012	belongs to the aldehyde dehydrogenase family
LH58_RS06350	COG0506	proline dehydrogenase activity
LH58_RS06370	COG0318	PFAM AMP-dependent synthetase and ligase
LH58_RS06380	COG0657	acetylesterase activity
LH58_RS06385	COG5651	PPE family
LH58_RS06400	COG3328	transposase activity
LH58_RS06405	COG0477	Major facilitator Superfamily
LH58_RS06430	COG1611	Belongs to the LOG family
LH58_RS06435	COG0318	PFAM AMP-dependent synthetase and ligase
LH58_RS06455	COG0519	Catalyzes the synthesis of GMP from XMP
LH58_RS06490	COG3559	Exporter of polyketide antibiotics
LH58_RS06495	COG1131	(ABC) transporter
LH58_RS06500	COG1309	transcriptional regulator
LH58_RS06515	COG5662	AntiSigma factor
LH58_RS06520	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LH58_RS06565	COG2239	Acts as a magnesium transporter
LH58_RS06600	COG0598	Magnesium transport protein CorA
LH58_RS06635	COG2026	Addiction module toxin, RelE StbE family
LH58_RS06640	COG2161	toxin-antitoxin pair type II binding
LH58_RS07050	COG0346	lactoylglutathione lyase activity
LH58_RS07135	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LH58_RS07340	COG2226	methyltransferase
LH58_RS07425	COG2072	flavoprotein involved in K transport
LH58_RS07465	COG0657	acetylesterase activity
LH58_RS07580	COG1481	regulation of sporulation
LH58_RS07595	COG0657	acetylesterase activity
LH58_RS07600	COG0318	PFAM AMP-dependent synthetase and ligase
LH58_RS07615	COG3391	amine dehydrogenase activity
LH58_RS07615	COG5651	PPE family
LH58_RS07630	COG1376	ErfK ybiS ycfS ynhG family protein
LH58_RS07655	COG0149	triose-phosphate isomerase activity
LH58_RS07675	COG0657	acetylesterase activity
LH58_RS07770	COG1131	(ABC) transporter
LH58_RS07795	COG0396	ATPase activity
LH58_RS07810	COG2151	metal-sulfur cluster biosynthetic enzyme
LH58_RS07815	COG1960	acyl-CoA dehydrogenase activity
LH58_RS07835	COG3118	belongs to the thioredoxin family
LH58_RS07845	COG0488	(ABC) transporter
LH58_RS07855	COG1309	transcriptional regulator
LH58_RS07860	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LH58_RS07870	COG0791	NLP P60 protein
LH58_RS07870	COG3883	PFAM NLP P60 protein
LH58_RS07880	COG0714	Associated with various cellular activities
LH58_RS07890	COG2304	oxidoreductase activity
LH58_RS07975	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LH58_RS07980	COG2226	methyltransferase
LH58_RS07985	COG3360	Dodecin
LH58_RS08010	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LH58_RS08070	COG0604	alcohol dehydrogenase
LH58_RS08070	COG1028	Short-chain dehydrogenase reductase Sdr
LH58_RS08070	COG3321	synthase
LH58_RS08100	COG2070	2-Nitropropane dioxygenase
LH58_RS08155	COG0300	oxidoreductase activity
LH58_RS08270	COG3883	PFAM NLP P60 protein
LH58_RS08270	COG0791	NLP P60 protein
LH58_RS08390	COG0483	inositol monophosphate 1-phosphatase activity
LH58_RS08405	COG0387	Pfam Sodium calcium exchanger
LH58_RS08460	COG1946	Acyl-CoA thioesterase
LH58_RS08465	COG0454	-acetyltransferase
LH58_RS08465	COG0456	acetyltransferase
LH58_RS08470	COG1132	(ABC) transporter
LH58_RS08475	COG4988	ABC transporter
LH58_RS08480	COG1294	oxidase, subunit
LH58_RS08485	COG1271	oxidase subunit
LH58_RS08560	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LH58_RS08610	COG0657	acetylesterase activity
LH58_RS08635	COG3391	amine dehydrogenase activity
LH58_RS08690	COG0604	alcohol dehydrogenase
LH58_RS08690	COG3321	synthase
LH58_RS08695	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LH58_RS08695	COG4221	oxidoreductase activity
LH58_RS08695	COG0604	alcohol dehydrogenase
LH58_RS08695	COG3321	synthase
LH58_RS08700	COG3321	synthase
LH58_RS08700	COG0604	alcohol dehydrogenase
LH58_RS08700	COG3321	synthase
LH58_RS08700	COG0604	alcohol dehydrogenase
LH58_RS08715	COG0488	(ABC) transporter
LH58_RS08770	COG1960	acyl-CoA dehydrogenase activity
LH58_RS08775	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
LH58_RS08795	COG2835	tetraacyldisaccharide 4'-kinase activity
LH58_RS08835	COG0647	UMP catabolic process
LH58_RS08875	COG0494	nUDIX hydrolase
LH58_RS08890	COG4122	O-methyltransferase activity
LH58_RS08895	COG1113	amino acid transport
LH58_RS08900	COG5651	PPE family
LH58_RS08915	COG0659	secondary active sulfate transmembrane transporter activity
LH58_RS08925	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LH58_RS08930	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LH58_RS09130	COG1716	ATPase activity
LH58_RS09130	COG1131	(ABC) transporter
LH58_RS09130	COG0842	Transport permease protein
LH58_RS09145	COG0318	PFAM AMP-dependent synthetase and ligase
LH58_RS09160	COG5651	PPE family
LH58_RS09160	COG5263	repeat protein
LH58_RS09175	COG0438	transferase activity, transferring glycosyl groups
LH58_RS09295	COG5651	PPE family
LH58_RS09305	COG5651	PPE family
LH58_RS09310	COG5651	PPE family
LH58_RS09340	COG1404	Belongs to the peptidase S8 family
LH58_RS09360	COG5651	PPE family
LH58_RS09380	COG3391	amine dehydrogenase activity
LH58_RS09385	COG0657	acetylesterase activity
LH58_RS09400	COG0657	acetylesterase activity
LH58_RS09425	COG1285	pathogenesis
LH58_RS09585	COG1253	flavin adenine dinucleotide binding
LH58_RS09590	COG1253	flavin adenine dinucleotide binding
LH58_RS09600	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LH58_RS09655	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LH58_RS09705	COG4221	oxidoreductase activity
LH58_RS09710	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LH58_RS09715	COG0183	Belongs to the thiolase family
LH58_RS09775	COG0174	glutamine synthetase
LH58_RS09795	COG0300	oxidoreductase activity
LH58_RS09815	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
LH58_RS09855	COG2070	2-Nitropropane dioxygenase
LH58_RS09860	COG1063	alcohol dehydrogenase
LH58_RS09865	COG1063	alcohol dehydrogenase
LH58_RS09875	COG1490	D-aminoacyl-tRNA deacylase activity
LH58_RS09905	COG1950	PFAM Membrane protein of
LH58_RS09910	COG1366	Belongs to the anti-sigma-factor antagonist family
LH58_RS09970	COG5263	repeat protein
LH58_RS09970	COG5651	PPE family
LH58_RS09970	COG5263	repeat protein
LH58_RS09970	COG5651	PPE family
LH58_RS09995	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LH58_RS10000	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LH58_RS10010	COG0318	PFAM AMP-dependent synthetase and ligase
LH58_RS10025	COG1028	Short-chain dehydrogenase reductase Sdr
LH58_RS10040	COG4977	sequence-specific DNA binding
LH58_RS10050	COG1960	acyl-CoA dehydrogenase activity
LH58_RS10055	COG1960	acyl-CoA dehydrogenase activity
LH58_RS10060	COG1024	Enoyl-CoA hydratase
LH58_RS10070	COG0543	2 iron, 2 sulfur cluster binding
LH58_RS10070	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LH58_RS10075	COG0596	Alpha beta hydrolase
LH58_RS10085	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LH58_RS10085	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LH58_RS10090	COG1028	Short-chain dehydrogenase reductase Sdr
LH58_RS10095	COG2337	Toxic component of a toxin-antitoxin (TA) module
LH58_RS10105	COG0653	protein targeting
LH58_RS10150	COG4691	Plasmid stability protein
LH58_RS10210	COG1309	transcriptional regulator
LH58_RS10245	COG1028	Short-chain dehydrogenase reductase Sdr
LH58_RS10395	COG2442	InterPro IPR007367
LH58_RS10410	COG1396	sequence-specific DNA binding
LH58_RS10490	COG0640	Transcriptional regulator
LH58_RS10505	COG1752	Esterase of the alpha-beta hydrolase superfamily
LH58_RS10510	COG3842	ATPase activity
LH58_RS10515	COG0395	ABC-type sugar transport system, permease component
LH58_RS10520	COG1175	transmembrane transport
LH58_RS10535	COG1335	isochorismatase
LH58_RS10560	COG0604	alcohol dehydrogenase
LH58_RS10560	COG3321	synthase
LH58_RS10620	COG0803	Belongs to the bacterial solute-binding protein 9 family
LH58_RS10645	COG2337	Toxic component of a toxin-antitoxin (TA) module
LH58_RS10670	COG2367	Beta-lactamase
LH58_RS10780	COG2801	Transposase and inactivated derivatives
LH58_RS10850	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LH58_RS10855	COG4279	zinc finger
LH58_RS10860	COG1848	Toxic component of a toxin-antitoxin (TA) module. An RNase
LH58_RS10870	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
LH58_RS10955	COG5651	PPE family
LH58_RS10960	COG1410	methionine synthase
LH58_RS10960	COG0646	methionine synthase
LH58_RS10990	COG1028	Short-chain dehydrogenase reductase Sdr
LH58_RS11045	COG0167	dihydroorotate dehydrogenase activity
LH58_RS11055	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LH58_RS11110	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LH58_RS11175	COG0768	penicillin binding
LH58_RS11215	COG0142	geranyltranstransferase activity
LH58_RS11240	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
LH58_RS11270	COG0003	Pfam Anion-transporting ATPase
LH58_RS11370	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LH58_RS11530	COG3744	PilT protein domain protein
LH58_RS11695	COG0815	Transfers the fatty acyl group on membrane lipoproteins
LH58_RS11700	COG4221	oxidoreductase activity
LH58_RS11795	COG0657	acetylesterase activity
LH58_RS11935	COG2442	InterPro IPR007367
LH58_RS11995	COG0395	ABC-type sugar transport system, permease component
LH58_RS12010	COG0531	amino acid
LH58_RS12015	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LH58_RS12020	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LH58_RS12025	COG1834	amidinotransferase
LH58_RS12030	COG1522	sequence-specific DNA binding
LH58_RS12060	COG2223	nitrite transmembrane transporter activity
LH58_RS12095	COG1045	serine acetyltransferase
LH58_RS12110	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LH58_RS12235	COG0657	acetylesterase activity
LH58_RS12250	COG1420	regulation of RNA biosynthetic process
LH58_RS12280	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LH58_RS12300	COG1021	2,3-dihydroxybenzoate-AMP ligase
LH58_RS12365	COG1297	OPT oligopeptide transporter protein
LH58_RS12395	COG4208	sulfate ABC transporter
LH58_RS12405	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
LH58_RS12420	COG3387	PFAM Glycoside hydrolase 15-related
LH58_RS12460	COG1305	Transglutaminase-like
LH58_RS12490	COG1555	photosystem II stabilization
LH58_RS12490	COG1596	polysaccharide export
LH58_RS12505	COG2755	lipolytic protein G-D-S-L family
LH58_RS12515	COG0799	negative regulation of ribosome biogenesis
LH58_RS12555	COG0542	response to heat
LH58_RS12580	COG5651	PPE family
LH58_RS12600	COG0668	transmembrane transport
LH58_RS12605	COG5002	protein histidine kinase activity
LH58_RS12610	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LH58_RS12645	COG1301	dicarboxylic acid transport
LH58_RS12650	COG1530	ribonuclease E activity
LH58_RS12665	COG0285	dihydrofolate synthase activity
LH58_RS12675	COG3268	Saccharopine dehydrogenase
LH58_RS12680	COG1388	LysM domain
LH58_RS12700	COG1013	pyruvate-flavodoxin oxidoreductase activity
LH58_RS12705	COG0674	pyruvate-flavodoxin oxidoreductase activity
LH58_RS12705	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
LH58_RS12715	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LH58_RS12720	COG2040	homocysteine
LH58_RS12755	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LH58_RS12770	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LH58_RS12800	COG0366	Alpha amylase catalytic
LH58_RS12820	COG0824	Thioesterase
LH58_RS12825	COG2902	Dehydrogenase
LH58_RS12860	COG0657	acetylesterase activity
LH58_RS12930	COG1848	Toxic component of a toxin-antitoxin (TA) module. An RNase
LH58_RS12935	COG0508	dehydrogenase complex catalyzes the overall conversion of
LH58_RS12955	COG2030	dehydratase
LH58_RS12960	COG1960	acyl-CoA dehydrogenase activity
LH58_RS12970	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LH58_RS12985	COG0318	PFAM AMP-dependent synthetase and ligase
LH58_RS13005	COG0300	oxidoreductase activity
LH58_RS13010	COG0433	COG0433 Predicted ATPase
LH58_RS13025	COG3328	transposase activity
LH58_RS13065	COG1376	ErfK ybiS ycfS ynhG family protein
LH58_RS13105	COG3757	hydrolase, family 25
LH58_RS13120	COG1715	Restriction endonuclease
LH58_RS13220	COG1487	ribonuclease activity
LH58_RS13255	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LH58_RS13260	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LH58_RS13275	COG0432	Pfam Uncharacterised protein family UPF0047
LH58_RS13425	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LH58_RS13445	COG1022	Amp-dependent synthetase and ligase
LH58_RS13445	COG3320	Male sterility
LH58_RS13525	COG1946	Acyl-CoA thioesterase
LH58_RS13540	COG5651	PPE family
LH58_RS13580	COG3391	amine dehydrogenase activity
LH58_RS13585	COG4762	Protein conserved in bacteria
LH58_RS13705	COG1366	Belongs to the anti-sigma-factor antagonist family
LH58_RS13725	COG0640	Transcriptional regulator
LH58_RS13730	COG0798	PFAM Bile acid sodium symporter
LH58_RS13780	COG3328	transposase activity
LH58_RS13820	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LH58_RS13900	COG0531	amino acid
LH58_RS13905	COG0569	domain protein
LH58_RS14045	COG1388	LysM domain
LH58_RS14070	COG1960	acyl-CoA dehydrogenase activity
LH58_RS14075	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LH58_RS14105	COG1196	nuclear chromosome segregation
LH58_RS14150	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
LH58_RS14155	COG3391	amine dehydrogenase activity
LH58_RS14170	COG1842	Phage shock protein A
LH58_RS14185	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
LH58_RS14230	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
LH58_RS14280	COG1028	Short-chain dehydrogenase reductase Sdr
LH58_RS14345	COG1522	sequence-specific DNA binding
LH58_RS14400	COG1960	acyl-CoA dehydrogenase activity
LH58_RS14405	COG0183	Belongs to the thiolase family
LH58_RS14425	COG2977	Belongs to the P-Pant transferase superfamily
LH58_RS14430	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LH58_RS14460	COG2337	Toxic component of a toxin-antitoxin (TA) module
LH58_RS14465	COG3609	addiction module antidote protein, CC2985 family
LH58_RS14530	COG2801	Transposase and inactivated derivatives
LH58_RS14535	COG2963	transposase activity
LH58_RS14575	COG1353	crispr-associated protein
LH58_RS14610	COG3744	PilT protein domain protein
LH58_RS14615	COG4118	positive regulation of growth
LH58_RS14625	COG3842	ATPase activity
LH58_RS14630	COG1653	transport
LH58_RS14635	COG0395	ABC-type sugar transport system, permease component
LH58_RS14650	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LH58_RS14700	COG1648	precorrin-2 dehydrogenase activity
LH58_RS14700	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LH58_RS14745	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
LH58_RS14770	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LH58_RS14805	COG2161	toxin-antitoxin pair type II binding
LH58_RS14810	COG2026	Addiction module toxin, RelE StbE family
LH58_RS14890	COG0233	cytoplasmic translational termination
LH58_RS14900	COG0745	RESPONSE REGULATOR receiver
LH58_RS15035	COG1686	Belongs to the peptidase S11 family
LH58_RS15070	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
LH58_RS15305	COG0701	Predicted permease
LH58_RS15325	COG0742	ribosomal rna small subunit methyltransferase
LH58_RS15330	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LH58_RS15345	COG0657	acetylesterase activity
LH58_RS15350	COG0656	L-ascorbic acid biosynthetic process
LH58_RS15370	COG1461	Dihydroxyacetone kinase
LH58_RS15470	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LH58_RS15475	COG0179	Fumarylacetoacetate (FAA) hydrolase
LH58_RS15480	COG2271	Major facilitator Superfamily
LH58_RS15510	COG2972	Histidine kinase
LH58_RS15520	COG0390	transport system, permease component
LH58_RS15545	COG2259	Doxx family
LH58_RS15635	COG3328	transposase activity
LH58_RS15695	COG0110	maltose O-acetyltransferase activity
LH58_RS15700	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LH58_RS15730	COG1119	ATPase activity
LH58_RS15735	COG0560	Phosphoserine phosphatase
LH58_RS15735	COG3830	Belongs to the UPF0237 family
LH58_RS15780	COG1309	transcriptional regulator
LH58_RS15830	COG2186	Transcriptional regulator
LH58_RS15835	COG1960	acyl-CoA dehydrogenase activity
LH58_RS15850	COG1966	Carbon starvation protein
LH58_RS15935	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LH58_RS16000	COG2354	Protein conserved in bacteria
LH58_RS16025	COG0657	acetylesterase activity
LH58_RS16035	COG2337	Toxic component of a toxin-antitoxin (TA) module
LH58_RS16055	COG2884	Cell division ATP-binding protein ftsE
LH58_RS16065	COG0668	transmembrane transport
LH58_RS16080	COG0277	FAD linked oxidase domain protein
LH58_RS16100	COG2154	pterin-4-alpha-carbinolamine dehydratase
LH58_RS16110	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LH58_RS16125	COG3328	transposase activity
LH58_RS16150	COG3629	intracellular signal transduction
LH58_RS16175	COG2801	Transposase and inactivated derivatives
LH58_RS16225	COG0483	inositol monophosphate 1-phosphatase activity
LH58_RS16240	COG1960	acyl-CoA dehydrogenase activity
LH58_RS16245	COG0604	alcohol dehydrogenase
LH58_RS16245	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LH58_RS16245	COG3321	synthase
LH58_RS16245	COG4221	oxidoreductase activity
LH58_RS16365	COG0714	Associated with various cellular activities
LH58_RS16410	COG1309	transcriptional regulator
LH58_RS16420	COG0154	amidase activity
LH58_RS16435	COG0748	coenzyme F420 binding
LH58_RS16460	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
LH58_RS16465	COG1396	sequence-specific DNA binding
LH58_RS16495	COG2826	transposase and inactivated derivatives, IS30 family
LH58_RS16540	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LH58_RS16585	COG0596	Alpha beta hydrolase
LH58_RS16590	COG3695	enzyme binding
LH58_RS16630	COG0513	Belongs to the DEAD box helicase family
LH58_RS16645	COG0406	alpha-ribazole phosphatase activity
LH58_RS16665	COG1597	lipid kinase activity
LH58_RS16700	COG1028	Short-chain dehydrogenase reductase Sdr
LH58_RS16710	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LH58_RS16720	COG2135	peptidase activity
LH58_RS16730	COG1162	GTPase activity
LH58_RS16750	COG2326	polyphosphate kinase activity
LH58_RS16765	COG4651	solute:proton antiporter activity
LH58_RS16765	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LH58_RS16775	COG2020	methyltransferase activity
LH58_RS16790	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LH58_RS16845	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LH58_RS16850	COG0531	amino acid
LH58_RS16855	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LH58_RS16860	COG1482	cell wall glycoprotein biosynthetic process
LH58_RS16870	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LH58_RS16920	COG1316	TRANSCRIPTIONal
LH58_RS16945	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LH58_RS16950	COG0659	secondary active sulfate transmembrane transporter activity
LH58_RS16985	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LH58_RS17010	COG4770	biotin carboxylase activity
LH58_RS17040	COG1522	sequence-specific DNA binding
LH58_RS17050	COG1012	belongs to the aldehyde dehydrogenase family
LH58_RS17060	COG1309	transcriptional regulator
LH58_RS17065	COG1201	RNA secondary structure unwinding
LH58_RS17080	COG3408	Glycogen debranching enzyme
LH58_RS17080	COG3119	arylsulfatase activity
LH58_RS17085	COG0564	pseudouridine synthase activity
LH58_RS17110	COG0406	alpha-ribazole phosphatase activity
LH58_RS17130	COG1597	lipid kinase activity
LH58_RS17165	COG1028	Short-chain dehydrogenase reductase Sdr
LH58_RS17180	COG2135	peptidase activity
LH58_RS17190	COG1162	GTPase activity
LH58_RS17210	COG1522	sequence-specific DNA binding
LH58_RS17220	COG1012	belongs to the aldehyde dehydrogenase family
LH58_RS17230	COG1309	transcriptional regulator
LH58_RS17235	COG1201	RNA secondary structure unwinding
LH58_RS17250	COG3119	arylsulfatase activity
LH58_RS17250	COG3408	Glycogen debranching enzyme
LH58_RS17255	COG0564	pseudouridine synthase activity
LH58_RS17280	COG0406	alpha-ribazole phosphatase activity
LH58_RS17300	COG1597	lipid kinase activity
LH58_RS17335	COG1028	Short-chain dehydrogenase reductase Sdr
LH58_RS17350	COG2135	peptidase activity
LH58_RS17360	COG1162	GTPase activity
LH58_RS17380	COG1522	sequence-specific DNA binding
LH58_RS17390	COG1012	belongs to the aldehyde dehydrogenase family
LH58_RS17400	COG1309	transcriptional regulator
LH58_RS17405	COG1201	RNA secondary structure unwinding
LH58_RS17420	COG3408	Glycogen debranching enzyme
LH58_RS17420	COG3119	arylsulfatase activity
LH58_RS17425	COG0564	pseudouridine synthase activity
LH58_RS17450	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
LH58_RS17450	COG1473	amidohydrolase
LH58_RS17465	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LH58_RS17475	COG3511	phospholipase C
LH58_RS17510	COG2009	succinate dehydrogenase
LH58_RS17520	COG1053	succinate dehydrogenase
LH58_RS17525	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LH58_RS17555	COG2154	pterin-4-alpha-carbinolamine dehydratase
LH58_RS17580	COG3547	Transposase (IS116 IS110 IS902 family)
LH58_RS17585	COG1595	DNA-templated transcription, initiation
LH58_RS17590	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LH58_RS17595	COG1686	Belongs to the peptidase S11 family
LH58_RS17600	COG2814	Major facilitator Superfamily
LH58_RS17605	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LH58_RS17615	COG0789	Transcriptional regulator
LH58_RS17640	COG2873	o-acetylhomoserine
LH58_RS17655	COG5651	PPE family
LH58_RS17655	COG5651	PPE family
LH58_RS17675	COG5651	PPE family
LH58_RS17675	COG5651	PPE family
LH58_RS17700	COG5651	PPE family
LH58_RS17710	COG0277	FAD linked oxidase domain protein
LH58_RS17750	COG0842	Transport permease protein
LH58_RS17750	COG1131	(ABC) transporter
LH58_RS17750	COG1716	ATPase activity
LH58_RS17755	COG1357	PFAM Pentapeptide repeats (8 copies)
LH58_RS17770	COG2018	Roadblock/LC7 domain
LH58_RS17780	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LH58_RS17805	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LH58_RS17815	COG1024	Enoyl-CoA hydratase
LH58_RS17830	COG1657	PFAM Prenyltransferase squalene oxidase
LH58_RS17840	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LH58_RS17850	COG0142	geranyltranstransferase activity
LH58_RS17855	COG1848	Toxic component of a toxin-antitoxin (TA) module. An RNase
LH58_RS17880	COG2030	dehydratase
LH58_RS17885	COG0406	alpha-ribazole phosphatase activity
LH58_RS17895	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LH58_RS18040	COG0456	acetyltransferase
LH58_RS18065	COG5651	PPE family
LH58_RS18070	COG2801	Transposase and inactivated derivatives
LH58_RS18075	COG3328	transposase activity
LH58_RS18080	COG0076	glutamate decarboxylase activity
LH58_RS18140	COG4842	Belongs to the WXG100 family
LH58_RS18145	COG4842	Belongs to the WXG100 family
LH58_RS18155	COG1674	ftsk spoiiie
LH58_RS18165	COG1404	Belongs to the peptidase S8 family
LH58_RS18225	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LH58_RS18250	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LH58_RS18255	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LH58_RS18260	COG0028	Belongs to the TPP enzyme family
LH58_RS18280	COG0477	Major facilitator Superfamily
LH58_RS18290	COG5651	PPE family
LH58_RS18320	COG1316	TRANSCRIPTIONal
LH58_RS18325	COG1028	Short-chain dehydrogenase reductase Sdr
LH58_RS18330	COG2259	Doxx family
LH58_RS18335	COG0657	acetylesterase activity
LH58_RS18340	COG1695	Transcriptional regulator
LH58_RS18375	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LH58_RS18400	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LH58_RS18405	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LH58_RS18420	COG1960	acyl-CoA dehydrogenase activity
LH58_RS18425	COG1960	acyl-CoA dehydrogenase activity
LH58_RS18430	COG0318	PFAM AMP-dependent synthetase and ligase
LH58_RS18435	COG0657	acetylesterase activity
LH58_RS18455	COG0028	Belongs to the TPP enzyme family
LH58_RS18495	COG0657	acetylesterase activity
LH58_RS18505	COG1024	Enoyl-CoA hydratase
LH58_RS18520	COG2124	cytochrome p450
LH58_RS18530	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LH58_RS18540	COG0183	Belongs to the thiolase family
LH58_RS18545	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LH58_RS18560	COG4638	Rieske (2fe-2S)
LH58_RS18585	COG1028	Short-chain dehydrogenase reductase Sdr
LH58_RS18615	COG3971	2-oxopent-4-enoate hydratase activity
LH58_RS18620	COG1053	succinate dehydrogenase
LH58_RS18625	COG2030	dehydratase
LH58_RS18645	COG2030	dehydratase
LH58_RS18650	COG1960	acyl-CoA dehydrogenase activity
LH58_RS18655	COG1960	acyl-CoA dehydrogenase activity
LH58_RS18665	COG0183	Belongs to the thiolase family
LH58_RS18675	COG1028	Short-chain dehydrogenase reductase Sdr
LH58_RS18685	COG1024	Enoyl-CoA hydratase
LH58_RS18705	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LH58_RS18715	COG0183	Belongs to the thiolase family
LH58_RS18730	COG1028	Short-chain dehydrogenase reductase Sdr
LH58_RS18735	COG1960	acyl-CoA dehydrogenase activity
LH58_RS18740	COG0318	PFAM AMP-dependent synthetase and ligase
LH58_RS18745	COG1960	acyl-CoA dehydrogenase activity
LH58_RS18750	COG1960	acyl-CoA dehydrogenase activity
LH58_RS18755	COG1960	acyl-CoA dehydrogenase activity
LH58_RS18760	COG0436	Aminotransferase
LH58_RS18805	COG1960	acyl-CoA dehydrogenase activity
LH58_RS18810	COG1309	transcriptional regulator
LH58_RS18815	COG1609	Transcriptional regulator
LH58_RS18910	COG0739	heme binding
LH58_RS18990	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LH58_RS19040	COG2027	D-alanyl-D-alanine carboxypeptidase
LH58_RS19105	COG3328	transposase activity
LH58_RS19110	COG2184	nucleotidyltransferase activity
LH58_RS19130	COG0470	DNA polymerase III
LH58_RS19155	COG1111	helicase
LH58_RS19155	COG1205	dead DEAH box helicase
LH58_RS19160	COG0657	acetylesterase activity
LH58_RS19225	COG4172	Belongs to the ABC transporter superfamily
LH58_RS19230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LH58_RS19235	COG0601	transmembrane transport
LH58_RS19275	COG0494	nUDIX hydrolase
LH58_RS19300	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LH58_RS19335	COG1408	metallophosphoesterase
LH58_RS19340	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LH58_RS19385	COG0714	Associated with various cellular activities
LH58_RS19405	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LH58_RS19410	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LH58_RS19445	COG0121	glutamine amidotransferase
LH58_RS19450	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LH58_RS19500	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LH58_RS19525	COG0860	N-Acetylmuramoyl-L-alanine amidase
LH58_RS19540	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LH58_RS19550	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LH58_RS19575	COG1063	alcohol dehydrogenase
LH58_RS19580	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LH58_RS19580	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
LH58_RS19585	COG0477	Major facilitator Superfamily
LH58_RS19590	COG2226	methyltransferase
LH58_RS19600	COG1793	dna ligase
LH58_RS19650	COG2072	flavoprotein involved in K transport
LH58_RS19660	COG0640	Transcriptional regulator
LH58_RS19685	COG1569	PIN domain
LH58_RS19690	COG3311	Transcriptional regulator
LH58_RS19705	COG0590	tRNA wobble adenosine to inosine editing
LH58_RS19715	COG0287	Prephenate dehydrogenase
LH58_RS19735	COG0517	IMP dehydrogenase activity
LH58_RS19735	COG1125	glycine betaine transport
LH58_RS19745	COG5416	Lipopolysaccharide assembly protein A domain
LH58_RS19755	COG2015	COG2015, Alkyl sulfatase and related hydrolases
LH58_RS19765	COG2205	protein histidine kinase activity
LH58_RS19770	COG0745	RESPONSE REGULATOR receiver
LH58_RS19775	COG0739	heme binding
LH58_RS19905	COG1088	dTDP-glucose 4,6-dehydratase activity
LH58_RS19965	COG1234	tRNA 3'-trailer cleavage
LH58_RS19970	COG1960	acyl-CoA dehydrogenase activity
LH58_RS19980	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LH58_RS19985	COG3321	synthase
LH58_RS19985	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
LH58_RS19985	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LH58_RS19995	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
LH58_RS20010	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LH58_RS20025	COG1216	Glycosyl transferase, family 2
LH58_RS20045	COG0657	acetylesterase activity
LH58_RS20055	COG0561	phosphatase activity
LH58_RS20100	COG5651	PPE family
LH58_RS20115	COG3321	synthase
LH58_RS20115	COG1028	Short-chain dehydrogenase reductase Sdr
LH58_RS20115	COG0604	alcohol dehydrogenase
LH58_RS20160	COG2207	Transcriptional regulator
LH58_RS20195	COG1316	TRANSCRIPTIONal
LH58_RS20240	COG2119	membrane
LH58_RS20280	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LH58_RS20280	COG1796	DNA polymerase
LH58_RS20295	COG0070	glutamate synthase
LH58_RS20295	COG0067	glutamate synthase
LH58_RS20295	COG0069	glutamate synthase activity
LH58_RS20375	COG1404	Belongs to the peptidase S8 family
LH58_RS20415	COG5651	PPE family
LH58_RS20505	COG1595	DNA-templated transcription, initiation
LH58_RS20525	COG0860	N-Acetylmuramoyl-L-alanine amidase
LH58_RS20525	COG3409	Peptidoglycan-binding domain 1 protein
LH58_RS20540	COG1192	Involved in chromosome partitioning
LH58_RS20560	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
LH58_RS20570	COG0230	Belongs to the bacterial ribosomal protein bL34 family
LH58_RS20640	COG0657	acetylesterase activity
LH58_RS20670	COG4683	PFAM Phage derived protein Gp49-like (DUF891)