BWK49_RS22345 51b6d51651204f1edd06cfdc35cc02c8 309 Gene3D G3DSA:3.40.50.80 103 215 1.9E-19 T 06-07-2017 BWK49_RS22345 51b6d51651204f1edd06cfdc35cc02c8 309 Pfam PF00970 Oxidoreductase FAD-binding domain 8 101 2.2E-6 T 06-07-2017 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 BWK49_RS22345 51b6d51651204f1edd06cfdc35cc02c8 309 SUPERFAMILY SSF63380 3 99 2.27E-28 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 BWK49_RS22345 51b6d51651204f1edd06cfdc35cc02c8 309 PRINTS PR00409 Phthalate dioxygenase reductase family signature 29 39 1.2E-32 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 BWK49_RS22345 51b6d51651204f1edd06cfdc35cc02c8 309 PRINTS PR00409 Phthalate dioxygenase reductase family signature 188 196 1.2E-32 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 BWK49_RS22345 51b6d51651204f1edd06cfdc35cc02c8 309 PRINTS PR00409 Phthalate dioxygenase reductase family signature 51 65 1.2E-32 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 BWK49_RS22345 51b6d51651204f1edd06cfdc35cc02c8 309 PRINTS PR00409 Phthalate dioxygenase reductase family signature 75 89 1.2E-32 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 BWK49_RS22345 51b6d51651204f1edd06cfdc35cc02c8 309 PRINTS PR00409 Phthalate dioxygenase reductase family signature 39 51 1.2E-32 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 BWK49_RS22345 51b6d51651204f1edd06cfdc35cc02c8 309 PRINTS PR00409 Phthalate dioxygenase reductase family signature 111 130 1.2E-32 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 BWK49_RS22345 51b6d51651204f1edd06cfdc35cc02c8 309 PRINTS PR00409 Phthalate dioxygenase reductase family signature 89 103 1.2E-32 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 BWK49_RS22345 51b6d51651204f1edd06cfdc35cc02c8 309 PRINTS PR00409 Phthalate dioxygenase reductase family signature 136 145 1.2E-32 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 BWK49_RS22345 51b6d51651204f1edd06cfdc35cc02c8 309 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 236 300 1.4E-9 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 BWK49_RS22345 51b6d51651204f1edd06cfdc35cc02c8 309 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 263 271 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 BWK49_RS22345 51b6d51651204f1edd06cfdc35cc02c8 309 Pfam PF00175 Oxidoreductase NAD-binding domain 112 201 7.2E-5 T 06-07-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 BWK49_RS22345 51b6d51651204f1edd06cfdc35cc02c8 309 SUPERFAMILY SSF54292 213 307 1.7E-19 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 BWK49_RS22345 51b6d51651204f1edd06cfdc35cc02c8 309 Gene3D G3DSA:3.10.20.30 216 307 3.1E-18 T 06-07-2017 IPR012675 Beta-grasp domain BWK49_RS22345 51b6d51651204f1edd06cfdc35cc02c8 309 SUPERFAMILY SSF52343 97 222 7.2E-23 T 06-07-2017 BWK49_RS22345 51b6d51651204f1edd06cfdc35cc02c8 309 Gene3D G3DSA:2.40.30.10 4 99 5.5E-34 T 06-07-2017 BWK49_RS06110 aa5d362404ba60fcd3908ddde30eb703 204 SUPERFAMILY SSF46689 11 71 2.72E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS06110 aa5d362404ba60fcd3908ddde30eb703 204 Gene3D G3DSA:1.10.357.10 14 197 6.1E-33 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS06110 aa5d362404ba60fcd3908ddde30eb703 204 SUPERFAMILY SSF48498 85 194 1.41E-20 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS06110 aa5d362404ba60fcd3908ddde30eb703 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 1.5E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS06110 aa5d362404ba60fcd3908ddde30eb703 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 1.5E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS06110 aa5d362404ba60fcd3908ddde30eb703 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 67 8.2E-15 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS14290 e88b9ce891190652ace75283100f04d6 411 Pfam PF13823 Alcohol dehydrogenase GroES-associated 1 23 1.3E-9 T 06-07-2017 IPR027399 Alcohol dehydrogenase GroES-associated BWK49_RS14290 e88b9ce891190652ace75283100f04d6 411 SUPERFAMILY SSF50129 1 179 2.2E-56 T 06-07-2017 IPR011032 GroES-like BWK49_RS14290 e88b9ce891190652ace75283100f04d6 411 Pfam PF00107 Zinc-binding dehydrogenase 196 265 4.8E-11 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 BWK49_RS14290 e88b9ce891190652ace75283100f04d6 411 Gene3D G3DSA:3.40.50.720 188 331 1.5E-35 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS14290 e88b9ce891190652ace75283100f04d6 411 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 149 6.7E-25 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 BWK49_RS14290 e88b9ce891190652ace75283100f04d6 411 SUPERFAMILY SSF51735 163 351 3.31E-59 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS14290 e88b9ce891190652ace75283100f04d6 411 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 06-07-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 BWK49_RS14290 e88b9ce891190652ace75283100f04d6 411 Gene3D G3DSA:3.90.180.10 1 187 7.5E-48 T 06-07-2017 IPR011032 GroES-like BWK49_RS07005 784a58b2f6c5ecf7fb186b50fca83f7f 209 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 14 197 27.559 T 06-07-2017 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 BWK49_RS07005 784a58b2f6c5ecf7fb186b50fca83f7f 209 Gene3D G3DSA:3.40.50.170 13 205 2.1E-61 T 06-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 BWK49_RS07005 784a58b2f6c5ecf7fb186b50fca83f7f 209 SUPERFAMILY SSF53328 14 207 1.28E-55 T 06-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 BWK49_RS07005 784a58b2f6c5ecf7fb186b50fca83f7f 209 Pfam PF00551 Formyl transferase 14 191 4.5E-42 T 06-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 BWK49_RS07005 784a58b2f6c5ecf7fb186b50fca83f7f 209 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 13 199 3.3E-67 T 06-07-2017 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 BWK49_RS18690 3b1305d5710cc206673c3099bd331be7 591 Gene3D G3DSA:2.40.50.140 3 105 7.5E-37 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS18690 3b1305d5710cc206673c3099bd331be7 591 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 3 581 2.8E-202 T 06-07-2017 IPR004524 Aspartate-tRNA ligase, bacterial/mitochondrial-type GO:0005524|GO:0016874 Reactome: R-HSA-379726 BWK49_RS18690 3b1305d5710cc206673c3099bd331be7 591 Gene3D G3DSA:3.30.1360.30 275 403 1.6E-40 T 06-07-2017 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 BWK49_RS18690 3b1305d5710cc206673c3099bd331be7 591 Pfam PF01336 OB-fold nucleic acid binding domain 19 101 1.8E-17 T 06-07-2017 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 BWK49_RS18690 3b1305d5710cc206673c3099bd331be7 591 Pfam PF00152 tRNA synthetases class II (D, K and N) 117 557 2.5E-98 T 06-07-2017 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 BWK49_RS18690 3b1305d5710cc206673c3099bd331be7 591 SUPERFAMILY SSF50249 3 104 1.9E-29 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS18690 3b1305d5710cc206673c3099bd331be7 591 SUPERFAMILY SSF55261 287 409 4.14E-33 T 06-07-2017 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 BWK49_RS18690 3b1305d5710cc206673c3099bd331be7 591 PRINTS PR01042 Aspartyl-tRNA synthetase signature 206 219 1.8E-25 T 06-07-2017 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 BWK49_RS18690 3b1305d5710cc206673c3099bd331be7 591 PRINTS PR01042 Aspartyl-tRNA synthetase signature 474 490 1.8E-25 T 06-07-2017 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 BWK49_RS18690 3b1305d5710cc206673c3099bd331be7 591 PRINTS PR01042 Aspartyl-tRNA synthetase signature 518 532 1.8E-25 T 06-07-2017 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 BWK49_RS18690 3b1305d5710cc206673c3099bd331be7 591 PRINTS PR01042 Aspartyl-tRNA synthetase signature 189 201 1.8E-25 T 06-07-2017 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 BWK49_RS18690 3b1305d5710cc206673c3099bd331be7 591 Pfam PF02938 GAD domain 310 389 5.2E-11 T 06-07-2017 IPR029351 GAD domain Reactome: R-HSA-379726 BWK49_RS18690 3b1305d5710cc206673c3099bd331be7 591 Hamap MF_00044 Aspartate--tRNA(Asp) ligase [aspS]. 2 563 35.994 T 06-07-2017 BWK49_RS18690 3b1305d5710cc206673c3099bd331be7 591 Gene3D G3DSA:3.30.930.10 404 584 1.5E-103 T 06-07-2017 BWK49_RS18690 3b1305d5710cc206673c3099bd331be7 591 Gene3D G3DSA:3.30.930.10 134 274 1.5E-103 T 06-07-2017 BWK49_RS18690 3b1305d5710cc206673c3099bd331be7 591 SUPERFAMILY SSF55681 112 290 3.11E-96 T 06-07-2017 BWK49_RS18690 3b1305d5710cc206673c3099bd331be7 591 SUPERFAMILY SSF55681 414 583 3.11E-96 T 06-07-2017 BWK49_RS14215 c44df37e94bf0ede3dc52221a0da8f74 411 TIGRFAM TIGR03106 trio_M42_hydro: hydrolase, peptidase M42 family 11 354 5.4E-172 T 06-07-2017 IPR017537 Peptidase M42, hydrolase BWK49_RS14215 c44df37e94bf0ede3dc52221a0da8f74 411 SUPERFAMILY SSF101821 81 195 1.01E-24 T 06-07-2017 BWK49_RS14215 c44df37e94bf0ede3dc52221a0da8f74 411 Gene3D G3DSA:2.40.30.40 81 176 1.1E-23 T 06-07-2017 IPR023367 Peptidase M42, domain 2 BWK49_RS14215 c44df37e94bf0ede3dc52221a0da8f74 411 Gene3D G3DSA:3.40.630.10 179 353 4.8E-44 T 06-07-2017 BWK49_RS14215 c44df37e94bf0ede3dc52221a0da8f74 411 Gene3D G3DSA:3.40.630.10 12 80 4.8E-44 T 06-07-2017 BWK49_RS14215 c44df37e94bf0ede3dc52221a0da8f74 411 SUPERFAMILY SSF53187 187 353 6.02E-44 T 06-07-2017 BWK49_RS14215 c44df37e94bf0ede3dc52221a0da8f74 411 SUPERFAMILY SSF53187 15 91 6.02E-44 T 06-07-2017 BWK49_RS14215 c44df37e94bf0ede3dc52221a0da8f74 411 Pfam PF05343 M42 glutamyl aminopeptidase 56 346 1.0E-60 T 06-07-2017 IPR008007 Peptidase M42 BWK49_RS20125 460bf797bdecad74992770aa4a23f66e 79 Gene3D G3DSA:1.10.1470.10 12 63 2.8E-6 T 06-07-2017 IPR008462 CsbD-like BWK49_RS20125 460bf797bdecad74992770aa4a23f66e 79 SUPERFAMILY SSF69047 11 63 1.15E-6 T 06-07-2017 IPR008462 CsbD-like BWK49_RS07405 51e13cbbd67d73eef11abd1c8f03fdae 280 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 19 276 2.2E-81 T 06-07-2017 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 BWK49_RS07405 51e13cbbd67d73eef11abd1c8f03fdae 280 Gene3D G3DSA:3.20.20.140 15 277 5.4E-77 T 06-07-2017 BWK49_RS07405 51e13cbbd67d73eef11abd1c8f03fdae 280 Pfam PF01026 TatD related DNase 20 275 3.5E-66 T 06-07-2017 IPR001130 TatD family GO:0016788 BWK49_RS07405 51e13cbbd67d73eef11abd1c8f03fdae 280 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 212 228 - T 06-07-2017 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 BWK49_RS07405 51e13cbbd67d73eef11abd1c8f03fdae 280 SUPERFAMILY SSF51556 19 277 4.96E-73 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS07405 51e13cbbd67d73eef11abd1c8f03fdae 280 PIRSF PIRSF005902 9 280 2.8E-68 T 06-07-2017 IPR001130 TatD family GO:0016788 BWK49_RS08720 f3e6303b2f59a2ccf6496e270415181b 388 Gene3D G3DSA:3.30.70.1230 224 384 1.5E-23 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 BWK49_RS08720 f3e6303b2f59a2ccf6496e270415181b 388 SUPERFAMILY SSF55073 224 385 8.95E-34 T 06-07-2017 IPR029787 Nucleotide cyclase BWK49_RS08720 f3e6303b2f59a2ccf6496e270415181b 388 Pfam PF16701 Adenylate cyclase regulatory domain 20 204 6.8E-86 T 06-07-2017 IPR032026 Adenylate cyclase regulatory domain BWK49_RS08720 f3e6303b2f59a2ccf6496e270415181b 388 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 224 381 6.0E-15 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 BWK49_RS08720 f3e6303b2f59a2ccf6496e270415181b 388 SMART SM00044 179 363 1.8E-6 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 BWK49_RS27715 8beb16245200e4c5e20b3cb6cb0c6431 719 Gene3D G3DSA:2.40.30.10 313 432 5.4E-28 T 06-07-2017 BWK49_RS27715 8beb16245200e4c5e20b3cb6cb0c6431 719 SUPERFAMILY SSF54980 630 716 5.76E-22 T 06-07-2017 IPR009022 Elongation factor G, III-V domain BWK49_RS27715 8beb16245200e4c5e20b3cb6cb0c6431 719 Pfam PF00679 Elongation factor G C-terminus 628 712 3.6E-23 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain BWK49_RS27715 8beb16245200e4c5e20b3cb6cb0c6431 719 SMART SM00889 507 625 5.4E-62 T 06-07-2017 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 BWK49_RS27715 8beb16245200e4c5e20b3cb6cb0c6431 719 Pfam PF14492 Elongation Factor G, domain II 431 503 2.5E-23 T 06-07-2017 IPR009022 Elongation factor G, III-V domain BWK49_RS27715 8beb16245200e4c5e20b3cb6cb0c6431 719 Gene3D G3DSA:3.30.70.240 628 712 1.5E-24 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain BWK49_RS27715 8beb16245200e4c5e20b3cb6cb0c6431 719 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 23 161 5.2E-16 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 BWK49_RS27715 8beb16245200e4c5e20b3cb6cb0c6431 719 Pfam PF03764 Elongation factor G, domain IV 507 623 3.3E-42 T 06-07-2017 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 BWK49_RS27715 8beb16245200e4c5e20b3cb6cb0c6431 719 Pfam PF00009 Elongation factor Tu GTP binding domain 23 290 3.8E-38 T 06-07-2017 BWK49_RS27715 8beb16245200e4c5e20b3cb6cb0c6431 719 Gene3D G3DSA:3.30.230.10 511 627 1.7E-51 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup BWK49_RS27715 8beb16245200e4c5e20b3cb6cb0c6431 719 SMART SM00382 22 179 0.0066 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS27715 8beb16245200e4c5e20b3cb6cb0c6431 719 Gene3D G3DSA:3.40.50.300 20 296 2.4E-64 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS27715 8beb16245200e4c5e20b3cb6cb0c6431 719 Pfam PF03144 Elongation factor Tu domain 2 333 417 1.1E-11 T 06-07-2017 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 BWK49_RS27715 8beb16245200e4c5e20b3cb6cb0c6431 719 SUPERFAMILY SSF54980 431 508 4.93E-17 T 06-07-2017 IPR009022 Elongation factor G, III-V domain BWK49_RS27715 8beb16245200e4c5e20b3cb6cb0c6431 719 Gene3D G3DSA:3.30.70.870 433 503 2.6E-24 T 06-07-2017 BWK49_RS27715 8beb16245200e4c5e20b3cb6cb0c6431 719 SUPERFAMILY SSF54211 507 622 4.55E-38 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold BWK49_RS27715 8beb16245200e4c5e20b3cb6cb0c6431 719 SMART SM00838 627 715 1.0E-25 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain BWK49_RS27715 8beb16245200e4c5e20b3cb6cb0c6431 719 SUPERFAMILY SSF52540 20 291 8.55E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS27715 8beb16245200e4c5e20b3cb6cb0c6431 719 SUPERFAMILY SSF50447 314 428 4.01E-22 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain BWK49_RS27715 8beb16245200e4c5e20b3cb6cb0c6431 719 SUPERFAMILY SSF50447 258 284 4.01E-22 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain BWK49_RS28625 fffdedf2d3e1140cbbe8d5415e07b717 944 SUPERFAMILY SSF55464 37 341 3.11E-66 T 06-07-2017 BWK49_RS28625 fffdedf2d3e1140cbbe8d5415e07b717 944 SUPERFAMILY SSF52540 449 599 5.9E-25 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS28625 fffdedf2d3e1140cbbe8d5415e07b717 944 Pfam PF13604 AAA domain 451 646 3.4E-49 T 06-07-2017 BWK49_RS28625 fffdedf2d3e1140cbbe8d5415e07b717 944 SUPERFAMILY SSF52540 664 824 8.26E-28 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS28625 fffdedf2d3e1140cbbe8d5415e07b717 944 SUPERFAMILY SSF52540 561 625 8.26E-28 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS28625 fffdedf2d3e1140cbbe8d5415e07b717 944 Pfam PF08751 TrwC relaxase 14 321 1.7E-63 T 06-07-2017 IPR014862 TrwC relaxase BWK49_RS28625 fffdedf2d3e1140cbbe8d5415e07b717 944 Gene3D G3DSA:3.40.50.300 767 822 9.3E-20 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS28625 fffdedf2d3e1140cbbe8d5415e07b717 944 Gene3D G3DSA:3.40.50.300 580 691 9.3E-20 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS28625 fffdedf2d3e1140cbbe8d5415e07b717 944 Pfam PF13538 UvrD-like helicase C-terminal domain 778 816 6.1E-7 T 06-07-2017 IPR027785 UvrD-like helicase C-terminal domain BWK49_RS28625 fffdedf2d3e1140cbbe8d5415e07b717 944 SMART SM00382 466 595 8.7E-4 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS28625 fffdedf2d3e1140cbbe8d5415e07b717 944 Gene3D G3DSA:3.40.50.300 451 579 6.0E-8 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS17230 ae977925ac91779119a2bf6a9fb06ac9 557 SUPERFAMILY SSF52540 361 551 1.08E-40 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS17230 ae977925ac91779119a2bf6a9fb06ac9 557 Gene3D G3DSA:3.40.50.300 361 545 8.3E-42 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS17230 ae977925ac91779119a2bf6a9fb06ac9 557 Gene3D G3DSA:1.20.1560.10 20 324 1.5E-22 T 06-07-2017 BWK49_RS17230 ae977925ac91779119a2bf6a9fb06ac9 557 Pfam PF00005 ABC transporter 361 506 2.5E-26 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 BWK49_RS17230 ae977925ac91779119a2bf6a9fb06ac9 557 SMART SM00382 367 557 7.3E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS17230 ae977925ac91779119a2bf6a9fb06ac9 557 Pfam PF00664 ABC transporter transmembrane region 29 183 2.1E-7 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 BWK49_RS17230 ae977925ac91779119a2bf6a9fb06ac9 557 SUPERFAMILY SSF90123 20 328 5.23E-29 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 BWK49_RS17230 ae977925ac91779119a2bf6a9fb06ac9 557 ProSitePatterns PS00211 ABC transporters family signature. 479 493 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 BWK49_RS17230 ae977925ac91779119a2bf6a9fb06ac9 557 TIGRFAM TIGR02868 CydC: thiol reductant ABC exporter, CydC subunit 18 542 6.9E-175 T 06-07-2017 IPR014223 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC GO:0006810|GO:0016021|GO:0042626 BWK49_RS17015 8823ef901a0451aaaa5a6f39cbd11b26 64 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 17.809 T 06-07-2017 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 BWK49_RS17015 8823ef901a0451aaaa5a6f39cbd11b26 64 Pfam PF01632 Ribosomal protein L35 2 62 3.6E-25 T 06-07-2017 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS17015 8823ef901a0451aaaa5a6f39cbd11b26 64 SUPERFAMILY SSF143034 2 62 4.71E-21 T 06-07-2017 BWK49_RS17015 8823ef901a0451aaaa5a6f39cbd11b26 64 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 06-07-2017 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS17015 8823ef901a0451aaaa5a6f39cbd11b26 64 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 63 2.3E-26 T 06-07-2017 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 BWK49_RS17015 8823ef901a0451aaaa5a6f39cbd11b26 64 PRINTS PR00064 Ribosomal protein L35 signature 36 54 8.5E-18 T 06-07-2017 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 BWK49_RS17015 8823ef901a0451aaaa5a6f39cbd11b26 64 PRINTS PR00064 Ribosomal protein L35 signature 3 20 8.5E-18 T 06-07-2017 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 BWK49_RS17015 8823ef901a0451aaaa5a6f39cbd11b26 64 PRINTS PR00064 Ribosomal protein L35 signature 21 35 8.5E-18 T 06-07-2017 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 BWK49_RS25470 89c6a29df8bfa9da28294213c236e85e 287 Gene3D G3DSA:1.10.1040.10 193 287 7.5E-33 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 BWK49_RS25470 89c6a29df8bfa9da28294213c236e85e 287 SUPERFAMILY SSF48179 191 287 2.04E-29 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 BWK49_RS25470 89c6a29df8bfa9da28294213c236e85e 287 Gene3D G3DSA:3.40.50.720 5 192 7.4E-56 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS25470 89c6a29df8bfa9da28294213c236e85e 287 SUPERFAMILY SSF51735 6 188 2.2E-50 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS25470 89c6a29df8bfa9da28294213c236e85e 287 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 9 188 3.9E-58 T 06-07-2017 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 BWK49_RS25470 89c6a29df8bfa9da28294213c236e85e 287 PIRSF PIRSF000105 1 287 6.0E-81 T 06-07-2017 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 BWK49_RS25470 89c6a29df8bfa9da28294213c236e85e 287 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 191 287 5.1E-34 T 06-07-2017 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 BWK49_RS18075 74400b562a0a7dca00d6107c4c7ac65a 758 SUPERFAMILY SSF52540 39 115 1.15E-7 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS18075 74400b562a0a7dca00d6107c4c7ac65a 758 SUPERFAMILY SSF52540 142 244 1.15E-7 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS18075 74400b562a0a7dca00d6107c4c7ac65a 758 Pfam PF00196 Bacterial regulatory proteins, luxR family 697 750 1.6E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS18075 74400b562a0a7dca00d6107c4c7ac65a 758 Gene3D G3DSA:1.25.40.10 464 663 5.4E-18 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 BWK49_RS18075 74400b562a0a7dca00d6107c4c7ac65a 758 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 712 728 7.5E-7 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS18075 74400b562a0a7dca00d6107c4c7ac65a 758 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 728 740 7.5E-7 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS18075 74400b562a0a7dca00d6107c4c7ac65a 758 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 698 712 7.5E-7 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS18075 74400b562a0a7dca00d6107c4c7ac65a 758 SMART SM00421 695 752 2.9E-16 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS18075 74400b562a0a7dca00d6107c4c7ac65a 758 SUPERFAMILY SSF46894 694 758 4.08E-18 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 BWK49_RS18075 74400b562a0a7dca00d6107c4c7ac65a 758 SUPERFAMILY SSF48452 490 666 1.19E-11 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 BWK49_RS18075 74400b562a0a7dca00d6107c4c7ac65a 758 Gene3D G3DSA:3.40.50.300 38 94 6.8E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS18075 74400b562a0a7dca00d6107c4c7ac65a 758 Gene3D G3DSA:3.40.50.300 135 185 6.8E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS18075 74400b562a0a7dca00d6107c4c7ac65a 758 Gene3D G3DSA:1.10.10.10 696 758 3.3E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS18745 c2ce267c0a1c808a841ce3a7f45441bd 164 SUPERFAMILY SSF55961 4 156 2.02E-15 T 06-07-2017 BWK49_RS18745 c2ce267c0a1c808a841ce3a7f45441bd 164 Gene3D G3DSA:3.30.530.20 1 127 9.5E-9 T 06-07-2017 IPR023393 START-like domain BWK49_RS18745 c2ce267c0a1c808a841ce3a7f45441bd 164 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 3 153 4.6E-7 T 06-07-2017 IPR019587 Polyketide cyclase/dehydrase BWK49_RS09730 d6983242cad6e95622c4070e83851ad8 665 Gene3D G3DSA:3.40.50.20 2 129 2.0E-50 T 06-07-2017 IPR016185 Pre-ATP-grasp domain BWK49_RS09730 d6983242cad6e95622c4070e83851ad8 665 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 613 630 - T 06-07-2017 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 BWK49_RS09730 d6983242cad6e95622c4070e83851ad8 665 SUPERFAMILY SSF51246 333 447 4.39E-38 T 06-07-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 BWK49_RS09730 d6983242cad6e95622c4070e83851ad8 665 SMART SM00878 338 444 4.9E-52 T 06-07-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 BWK49_RS09730 d6983242cad6e95622c4070e83851ad8 665 Gene3D G3DSA:2.40.50.100 589 655 8.1E-19 T 06-07-2017 BWK49_RS09730 d6983242cad6e95622c4070e83851ad8 665 SUPERFAMILY SSF51230 584 655 3.4E-17 T 06-07-2017 IPR011053 Single hybrid motif BWK49_RS09730 d6983242cad6e95622c4070e83851ad8 665 SUPERFAMILY SSF52440 2 113 2.3E-47 T 06-07-2017 IPR016185 Pre-ATP-grasp domain BWK49_RS09730 d6983242cad6e95622c4070e83851ad8 665 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 324 9.7E-82 T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 BWK49_RS09730 d6983242cad6e95622c4070e83851ad8 665 SUPERFAMILY SSF56059 83 350 1.54E-66 T 06-07-2017 BWK49_RS09730 d6983242cad6e95622c4070e83851ad8 665 Pfam PF00364 Biotin-requiring enzyme 590 655 1.1E-13 T 06-07-2017 IPR000089 Biotin/lipoyl attachment BWK49_RS09730 d6983242cad6e95622c4070e83851ad8 665 Gene3D G3DSA:3.30.1490.20 130 202 1.4E-26 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 BWK49_RS09730 d6983242cad6e95622c4070e83851ad8 665 Pfam PF02785 Biotin carboxylase C-terminal domain 338 445 1.2E-33 T 06-07-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 BWK49_RS09730 d6983242cad6e95622c4070e83851ad8 665 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 110 1.5E-44 T 06-07-2017 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 BWK49_RS09730 d6983242cad6e95622c4070e83851ad8 665 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 BWK49_RS09730 d6983242cad6e95622c4070e83851ad8 665 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 288 295 - T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 BWK49_RS09730 d6983242cad6e95622c4070e83851ad8 665 Gene3D G3DSA:3.30.470.20 205 447 9.5E-99 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 BWK49_RS17570 6d9c7b8ba43c2ac389c6e09dd81d9776 314 Gene3D G3DSA:3.40.50.40 201 307 4.2E-26 T 06-07-2017 IPR027473 L-asparaginase, C-terminal domain Reactome: R-HSA-70614 BWK49_RS17570 6d9c7b8ba43c2ac389c6e09dd81d9776 314 SUPERFAMILY SSF53774 4 313 6.15E-77 T 06-07-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 BWK49_RS17570 6d9c7b8ba43c2ac389c6e09dd81d9776 314 Gene3D G3DSA:3.40.50.1170 6 189 3.5E-45 T 06-07-2017 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 BWK49_RS17570 6d9c7b8ba43c2ac389c6e09dd81d9776 314 PRINTS PR00139 Asparaginase/glutaminase family signature 10 21 3.2E-15 T 06-07-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 BWK49_RS17570 6d9c7b8ba43c2ac389c6e09dd81d9776 314 PRINTS PR00139 Asparaginase/glutaminase family signature 78 96 3.2E-15 T 06-07-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 BWK49_RS17570 6d9c7b8ba43c2ac389c6e09dd81d9776 314 PRINTS PR00139 Asparaginase/glutaminase family signature 248 266 3.2E-15 T 06-07-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 BWK49_RS17570 6d9c7b8ba43c2ac389c6e09dd81d9776 314 Pfam PF00710 Asparaginase, N-terminal 10 177 4.3E-41 T 06-07-2017 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 BWK49_RS17570 6d9c7b8ba43c2ac389c6e09dd81d9776 314 SMART SM00870 9 310 8.8E-93 T 06-07-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 BWK49_RS17570 6d9c7b8ba43c2ac389c6e09dd81d9776 314 PIRSF PIRSF500176 6 313 1.9E-83 T 06-07-2017 BWK49_RS17570 6d9c7b8ba43c2ac389c6e09dd81d9776 314 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 79 89 - T 06-07-2017 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 BWK49_RS17570 6d9c7b8ba43c2ac389c6e09dd81d9776 314 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 12 20 - T 06-07-2017 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 BWK49_RS17570 6d9c7b8ba43c2ac389c6e09dd81d9776 314 PIRSF PIRSF001220 4 313 4.8E-79 T 06-07-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Gene3D G3DSA:3.40.50.980 622 760 1.7E-39 T 06-07-2017 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 ProSitePatterns PS00455 Putative AMP-binding domain signature. 600 611 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 ProSitePatterns PS00012 Phosphopantetheine attachment site. 4153 4168 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Gene3D G3DSA:1.10.1200.10 2031 2094 6.5E-26 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Gene3D G3DSA:1.10.1200.10 5617 5681 8.2E-26 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Gene3D G3DSA:1.10.1200.10 4133 4194 7.4E-24 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Gene3D G3DSA:1.10.1200.10 3084 3146 1.1E-25 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Gene3D G3DSA:1.10.1200.10 6683 6746 8.3E-26 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Gene3D G3DSA:1.10.1200.10 7734 7799 9.0E-24 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Gene3D G3DSA:1.10.1200.10 961 1023 3.5E-24 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 SUPERFAMILY SSF52777 4206 4372 1.22E-24 T 06-07-2017 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2724 2735 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 ProSitePatterns PS00012 Phosphopantetheine attachment site. 6702 6717 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Gene3D G3DSA:3.30.300.30 2970 3083 2.8E-37 T 06-07-2017 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Gene3D G3DSA:3.30.300.30 7620 7733 1.9E-36 T 06-07-2017 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Gene3D G3DSA:3.30.300.30 4022 4132 8.8E-38 T 06-07-2017 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Gene3D G3DSA:3.30.300.30 5505 5616 2.6E-35 T 06-07-2017 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Gene3D G3DSA:3.30.300.30 847 960 5.4E-38 T 06-07-2017 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Gene3D G3DSA:3.30.300.30 6565 6682 6.4E-38 T 06-07-2017 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Gene3D G3DSA:3.30.300.30 1917 2030 3.2E-38 T 06-07-2017 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Gene3D G3DSA:3.40.50.720 7850 8156 2.3E-25 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 SUPERFAMILY SSF47336 4121 4193 1.44E-15 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 SUPERFAMILY SSF56801 2542 3092 1.31E-144 T 06-07-2017 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 SUPERFAMILY SSF52777 6764 6939 8.0E-43 T 06-07-2017 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Gene3D G3DSA:2.30.38.10 5420 5500 2.9E-22 T 06-07-2017 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Gene3D G3DSA:2.30.38.10 3935 4004 3.6E-21 T 06-07-2017 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Gene3D G3DSA:2.30.38.10 6483 6560 1.2E-21 T 06-07-2017 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Gene3D G3DSA:2.30.38.10 7537 7615 4.1E-22 T 06-07-2017 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Gene3D G3DSA:2.30.38.10 761 833 2.2E-20 T 06-07-2017 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Gene3D G3DSA:2.30.38.10 1834 1912 4.8E-21 T 06-07-2017 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Gene3D G3DSA:2.30.38.10 2886 2965 3.3E-21 T 06-07-2017 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 SUPERFAMILY SSF52777 3165 3340 4.45E-48 T 06-07-2017 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 SUPERFAMILY SSF52777 4675 4867 9.56E-42 T 06-07-2017 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 TIGRFAM TIGR01746 Thioester-redct: thioester reductase domain 7850 8255 1.9E-92 T 06-07-2017 IPR010080 Thioester reductase-like domain BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 SMART SM01294 3080 3144 0.0019 T 06-07-2017 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 4513 4670 1.3E-34 T 06-07-2017 IPR010060 Non-ribosomal peptide synthase BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1661 1672 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3103 3118 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Pfam PF00668 Condensation domain 5696 5998 7.3E-64 T 06-07-2017 IPR001242 Condensation domain BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Pfam PF00668 Condensation domain 6 300 2.4E-25 T 06-07-2017 IPR001242 Condensation domain BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Pfam PF00668 Condensation domain 1039 1341 8.8E-62 T 06-07-2017 IPR001242 Condensation domain BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Pfam PF00668 Condensation domain 2109 2411 7.4E-61 T 06-07-2017 IPR001242 Condensation domain BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Pfam PF00668 Condensation domain 4228 4498 6.2E-23 T 06-07-2017 IPR001242 Condensation domain BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Pfam PF00668 Condensation domain 3163 3464 1.2E-60 T 06-07-2017 IPR001242 Condensation domain BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Pfam PF00668 Condensation domain 6761 7063 2.6E-60 T 06-07-2017 IPR001242 Condensation domain BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Pfam PF00668 Condensation domain 4677 4964 2.1E-55 T 06-07-2017 IPR001242 Condensation domain BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 SUPERFAMILY SSF52777 5886 6133 5.23E-59 T 06-07-2017 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 SUPERFAMILY SSF56801 1477 2039 1.19E-146 T 06-07-2017 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Gene3D G3DSA:3.40.50.980 3633 3785 2.9E-45 T 06-07-2017 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Gene3D G3DSA:3.40.50.980 2579 2732 7.1E-45 T 06-07-2017 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Gene3D G3DSA:3.40.50.980 1517 1670 3.1E-44 T 06-07-2017 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Gene3D G3DSA:3.40.50.980 5123 5273 1.3E-46 T 06-07-2017 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Gene3D G3DSA:3.40.50.980 456 621 1.7E-44 T 06-07-2017 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Gene3D G3DSA:3.40.50.980 7232 7384 2.6E-46 T 06-07-2017 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Gene3D G3DSA:3.40.50.980 6167 6320 1.0E-44 T 06-07-2017 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 SUPERFAMILY SSF56801 3594 4142 2.62E-142 T 06-07-2017 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Pfam PF13193 AMP-binding enzyme C-terminal domain 2983 3054 5.1E-10 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Pfam PF13193 AMP-binding enzyme C-terminal domain 6578 6649 2.2E-11 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Pfam PF13193 AMP-binding enzyme C-terminal domain 860 931 9.3E-10 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Pfam PF13193 AMP-binding enzyme C-terminal domain 1930 2001 5.1E-10 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Pfam PF13193 AMP-binding enzyme C-terminal domain 5518 5589 1.3E-9 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Pfam PF13193 AMP-binding enzyme C-terminal domain 7633 7704 7.2E-9 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Pfam PF13193 AMP-binding enzyme C-terminal domain 4035 4105 1.8E-12 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 ProSitePatterns PS00012 Phosphopantetheine attachment site. 980 995 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 SMART SM00823 Phosphopantetheine attachment site 4129 4197 0.04 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 SMART SM00823 Phosphopantetheine attachment site 2026 2095 3.7E-8 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 SMART SM00823 Phosphopantetheine attachment site 5613 5682 9.3E-7 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 SMART SM00823 Phosphopantetheine attachment site 956 1025 8.5E-4 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 SMART SM00823 Phosphopantetheine attachment site 3079 3148 1.1E-7 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 SMART SM00823 Phosphopantetheine attachment site 6678 6747 3.7E-7 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 SMART SM00823 Phosphopantetheine attachment site 7729 7798 7.8E-6 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 SUPERFAMILY SSF52777 189 426 9.67E-25 T 06-07-2017 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 SUPERFAMILY SSF56801 420 969 4.19E-142 T 06-07-2017 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 SUPERFAMILY SSF47336 2018 2092 1.06E-19 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Pfam PF13745 HxxPF-repeated domain 3486 3581 2.8E-28 T 06-07-2017 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Pfam PF13745 HxxPF-repeated domain 7085 7181 1.3E-29 T 06-07-2017 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Pfam PF13745 HxxPF-repeated domain 2433 2527 2.1E-27 T 06-07-2017 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Pfam PF13745 HxxPF-repeated domain 1363 1464 2.7E-25 T 06-07-2017 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Pfam PF13745 HxxPF-repeated domain 6020 6115 2.9E-29 T 06-07-2017 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 SUPERFAMILY SSF47336 3071 3141 2.22E-18 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Pfam PF07993 Male sterility protein 7853 8119 5.9E-56 T 06-07-2017 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 SUPERFAMILY SSF52777 1042 1217 8.56E-49 T 06-07-2017 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 SUPERFAMILY SSF52777 4391 4653 5.56E-24 T 06-07-2017 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 SUPERFAMILY SSF56801 7194 7742 8.9E-144 T 06-07-2017 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 SUPERFAMILY SSF51735 7849 8173 2.88E-27 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Gene3D G3DSA:3.30.559.10 4681 4846 5.6E-5 T 06-07-2017 IPR023213 Chloramphenicol acetyltransferase-like domain Reactome: R-HSA-389661 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Pfam PF00501 AMP-binding enzyme 3638 4027 2.0E-88 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Pfam PF00501 AMP-binding enzyme 461 852 6.8E-84 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Pfam PF00501 AMP-binding enzyme 5128 5510 3.6E-85 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Pfam PF00501 AMP-binding enzyme 2588 2975 1.9E-90 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Pfam PF00501 AMP-binding enzyme 7237 7625 1.0E-87 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Pfam PF00501 AMP-binding enzyme 6172 6570 1.6E-86 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Pfam PF00501 AMP-binding enzyme 1522 1922 1.5E-89 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 ProSitePatterns PS00012 Phosphopantetheine attachment site. 5637 5652 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 SUPERFAMILY SSF52777 1229 1488 6.0E-58 T 06-07-2017 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 SUPERFAMILY SSF56801 6129 6691 1.1E-142 T 06-07-2017 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 SUPERFAMILY SSF52777 5699 5874 2.33E-49 T 06-07-2017 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 SUPERFAMILY SSF56801 5085 5621 1.57E-143 T 06-07-2017 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Pfam PF00550 Phosphopantetheine attachment site 4132 4192 4.1E-9 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Pfam PF00550 Phosphopantetheine attachment site 3081 3141 2.9E-13 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Pfam PF00550 Phosphopantetheine attachment site 959 1018 4.9E-11 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Pfam PF00550 Phosphopantetheine attachment site 2029 2088 4.5E-14 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Pfam PF00550 Phosphopantetheine attachment site 6681 6743 2.9E-12 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Pfam PF00550 Phosphopantetheine attachment site 7737 7793 5.8E-13 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Pfam PF00550 Phosphopantetheine attachment site 5616 5678 6.1E-13 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 SUPERFAMILY SSF52777 3352 3604 3.56E-57 T 06-07-2017 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 SUPERFAMILY SSF52777 2112 2287 9.56E-48 T 06-07-2017 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 SUPERFAMILY SSF47336 5605 5678 3.14E-19 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 SUPERFAMILY SSF52777 10 183 1.33E-25 T 06-07-2017 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 SUPERFAMILY SSF52777 6953 7201 5.0E-56 T 06-07-2017 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2050 2065 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 SUPERFAMILY SSF52777 4853 5089 1.22E-54 T 06-07-2017 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 ProSitePatterns PS00455 Putative AMP-binding domain signature. 5265 5276 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 SUPERFAMILY SSF47336 6670 6743 3.01E-19 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 ProSitePatterns PS00455 Putative AMP-binding domain signature. 3777 3788 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2605 2999 3.9E-129 T 06-07-2017 IPR010071 Amino acid adenylation domain BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 5149 5534 4.5E-126 T 06-07-2017 IPR010071 Amino acid adenylation domain BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1543 1946 6.4E-133 T 06-07-2017 IPR010071 Amino acid adenylation domain BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 7258 7649 5.7E-129 T 06-07-2017 IPR010071 Amino acid adenylation domain BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 6193 6594 1.6E-131 T 06-07-2017 IPR010071 Amino acid adenylation domain BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 482 876 3.8E-124 T 06-07-2017 IPR010071 Amino acid adenylation domain BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 3659 4051 3.4E-125 T 06-07-2017 IPR010071 Amino acid adenylation domain BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 SUPERFAMILY SSF52777 2301 2552 3.89E-55 T 06-07-2017 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 SUPERFAMILY SSF47336 948 1021 8.51E-18 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 SUPERFAMILY SSF47336 7721 7794 5.89E-18 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Gene3D G3DSA:3.40.50.980 2733 2873 1.4E-38 T 06-07-2017 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Gene3D G3DSA:3.40.50.980 3786 3934 2.4E-38 T 06-07-2017 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Gene3D G3DSA:3.40.50.980 7385 7536 2.5E-33 T 06-07-2017 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Gene3D G3DSA:3.40.50.980 6321 6482 3.3E-39 T 06-07-2017 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Gene3D G3DSA:3.40.50.980 5274 5411 4.2E-35 T 06-07-2017 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 Gene3D G3DSA:3.40.50.980 1671 1833 1.8E-40 T 06-07-2017 BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 ProSitePatterns PS00012 Phosphopantetheine attachment site. 7753 7768 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site BWK49_RS17600 06cc380b4ac76e609418c87df085f4ed 8256 ProSitePatterns PS00455 Putative AMP-binding domain signature. 6311 6322 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS05125 6fc2b3ddec516c95a1042a5c227b18aa 411 Pfam PF00665 Integrase core domain 253 358 2.7E-9 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 BWK49_RS05125 6fc2b3ddec516c95a1042a5c227b18aa 411 Pfam PF13384 Homeodomain-like domain 12 54 6.8E-7 T 06-07-2017 BWK49_RS05125 6fc2b3ddec516c95a1042a5c227b18aa 411 Gene3D G3DSA:3.30.420.10 255 397 2.5E-6 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS05125 6fc2b3ddec516c95a1042a5c227b18aa 411 Gene3D G3DSA:1.10.10.60 75 110 4.5E-4 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS05125 6fc2b3ddec516c95a1042a5c227b18aa 411 SUPERFAMILY SSF53098 253 397 1.8E-18 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS05125 6fc2b3ddec516c95a1042a5c227b18aa 411 SUPERFAMILY SSF46689 70 172 4.26E-6 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS05125 6fc2b3ddec516c95a1042a5c227b18aa 411 Pfam PF13936 Helix-turn-helix domain 72 115 9.8E-17 T 06-07-2017 IPR025246 Transposase IS30-like HTH domain BWK49_RS05600 6fc2b3ddec516c95a1042a5c227b18aa 411 Pfam PF00665 Integrase core domain 253 358 2.7E-9 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 BWK49_RS05600 6fc2b3ddec516c95a1042a5c227b18aa 411 Pfam PF13384 Homeodomain-like domain 12 54 6.8E-7 T 06-07-2017 BWK49_RS05600 6fc2b3ddec516c95a1042a5c227b18aa 411 Gene3D G3DSA:3.30.420.10 255 397 2.5E-6 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS05600 6fc2b3ddec516c95a1042a5c227b18aa 411 Gene3D G3DSA:1.10.10.60 75 110 4.5E-4 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS05600 6fc2b3ddec516c95a1042a5c227b18aa 411 SUPERFAMILY SSF53098 253 397 1.8E-18 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS05600 6fc2b3ddec516c95a1042a5c227b18aa 411 SUPERFAMILY SSF46689 70 172 4.26E-6 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS05600 6fc2b3ddec516c95a1042a5c227b18aa 411 Pfam PF13936 Helix-turn-helix domain 72 115 9.8E-17 T 06-07-2017 IPR025246 Transposase IS30-like HTH domain BWK49_RS00905 ceeb89b748a5373113b1bf74d025816c 292 Gene3D G3DSA:1.10.10.10 104 162 2.8E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS00905 ceeb89b748a5373113b1bf74d025816c 292 Pfam PF04542 Sigma-70 region 2 15 78 8.1E-13 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS00905 ceeb89b748a5373113b1bf74d025816c 292 SUPERFAMILY SSF88946 11 92 9.42E-16 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS00905 ceeb89b748a5373113b1bf74d025816c 292 Gene3D G3DSA:1.10.1740.10 11 102 5.9E-16 T 06-07-2017 BWK49_RS00905 ceeb89b748a5373113b1bf74d025816c 292 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 12 161 1.9E-20 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS00905 ceeb89b748a5373113b1bf74d025816c 292 Pfam PF08281 Sigma-70, region 4 110 161 1.1E-10 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS00905 ceeb89b748a5373113b1bf74d025816c 292 SUPERFAMILY SSF88659 104 163 6.54E-11 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS15770 54cdc5e6b5d73a96e3d6ab1b736a6b27 281 Pfam PF09339 IclR helix-turn-helix domain 12 60 1.3E-13 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 BWK49_RS15770 54cdc5e6b5d73a96e3d6ab1b736a6b27 281 Pfam PF01614 Bacterial transcriptional regulator 127 240 4.4E-23 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal BWK49_RS15770 54cdc5e6b5d73a96e3d6ab1b736a6b27 281 Gene3D G3DSA:3.30.450.40 75 246 1.1E-41 T 06-07-2017 IPR029016 GAF domain-like BWK49_RS15770 54cdc5e6b5d73a96e3d6ab1b736a6b27 281 Gene3D G3DSA:1.10.10.10 10 74 3.0E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS15770 54cdc5e6b5d73a96e3d6ab1b736a6b27 281 SMART SM00346 9 96 5.8E-18 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 BWK49_RS15770 54cdc5e6b5d73a96e3d6ab1b736a6b27 281 SUPERFAMILY SSF55781 64 241 3.53E-37 T 06-07-2017 IPR029016 GAF domain-like BWK49_RS15770 54cdc5e6b5d73a96e3d6ab1b736a6b27 281 SUPERFAMILY SSF46785 12 79 2.73E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS19990 2d0e47eec976921d257519a1887c0430 459 PIRSF PIRSF000350 1 444 3.1E-80 T 06-07-2017 BWK49_RS19990 2d0e47eec976921d257519a1887c0430 459 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 320 2.1E-48 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS19990 2d0e47eec976921d257519a1887c0430 459 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 345 454 2.7E-28 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 BWK49_RS19990 2d0e47eec976921d257519a1887c0430 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 174 199 8.7E-42 T 06-07-2017 BWK49_RS19990 2d0e47eec976921d257519a1887c0430 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 341 362 8.7E-42 T 06-07-2017 BWK49_RS19990 2d0e47eec976921d257519a1887c0430 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 258 272 8.7E-42 T 06-07-2017 BWK49_RS19990 2d0e47eec976921d257519a1887c0430 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 8.7E-42 T 06-07-2017 BWK49_RS19990 2d0e47eec976921d257519a1887c0430 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 138 147 8.7E-42 T 06-07-2017 BWK49_RS19990 2d0e47eec976921d257519a1887c0430 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 300 307 8.7E-42 T 06-07-2017 BWK49_RS19990 2d0e47eec976921d257519a1887c0430 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 406 421 8.7E-42 T 06-07-2017 BWK49_RS19990 2d0e47eec976921d257519a1887c0430 459 SUPERFAMILY SSF55424 342 456 9.97E-31 T 06-07-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 BWK49_RS19990 2d0e47eec976921d257519a1887c0430 459 TIGRFAM TIGR03452 mycothione_red: mycothione reductase 3 458 7.7E-235 T 06-07-2017 IPR017817 Mycothione reductase MetaCyc: PWY-6421 BWK49_RS19990 2d0e47eec976921d257519a1887c0430 459 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 36 46 - T 06-07-2017 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 BWK49_RS19990 2d0e47eec976921d257519a1887c0430 459 Gene3D G3DSA:3.30.390.30 338 456 6.8E-38 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 BWK49_RS19990 2d0e47eec976921d257519a1887c0430 459 Gene3D G3DSA:3.50.50.60 136 251 3.9E-28 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS19990 2d0e47eec976921d257519a1887c0430 459 Gene3D G3DSA:3.50.50.60 3 135 2.1E-26 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS19990 2d0e47eec976921d257519a1887c0430 459 Gene3D G3DSA:3.50.50.60 252 328 4.0E-22 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS19990 2d0e47eec976921d257519a1887c0430 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 174 192 2.4E-25 T 06-07-2017 BWK49_RS19990 2d0e47eec976921d257519a1887c0430 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 2.4E-25 T 06-07-2017 BWK49_RS19990 2d0e47eec976921d257519a1887c0430 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 257 273 2.4E-25 T 06-07-2017 BWK49_RS19990 2d0e47eec976921d257519a1887c0430 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 135 153 2.4E-25 T 06-07-2017 BWK49_RS19990 2d0e47eec976921d257519a1887c0430 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 285 307 2.4E-25 T 06-07-2017 BWK49_RS19990 2d0e47eec976921d257519a1887c0430 459 SUPERFAMILY SSF51905 4 375 5.59E-41 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS05365 1864bfc6a5ed09b3f9415a3551201c80 382 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 130 220 6.6E-22 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 BWK49_RS05365 1864bfc6a5ed09b3f9415a3551201c80 382 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 234 382 3.9E-40 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS05365 1864bfc6a5ed09b3f9415a3551201c80 382 SUPERFAMILY SSF47203 233 382 1.3E-45 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS05365 1864bfc6a5ed09b3f9415a3551201c80 382 Gene3D G3DSA:1.10.540.10 13 127 8.0E-34 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS05365 1864bfc6a5ed09b3f9415a3551201c80 382 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 15 126 7.3E-31 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS05365 1864bfc6a5ed09b3f9415a3551201c80 382 Gene3D G3DSA:2.40.110.10 130 222 2.7E-34 T 06-07-2017 BWK49_RS05365 1864bfc6a5ed09b3f9415a3551201c80 382 SUPERFAMILY SSF56645 13 246 3.4E-75 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS05365 1864bfc6a5ed09b3f9415a3551201c80 382 Gene3D G3DSA:1.20.140.10 223 382 6.5E-53 T 06-07-2017 BWK49_RS25250 a9954755be3f0d83a74364eaeb1ee232 329 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 127 141 1.7E-58 T 06-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 BWK49_RS25250 a9954755be3f0d83a74364eaeb1ee232 329 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 302 321 1.7E-58 T 06-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 BWK49_RS25250 a9954755be3f0d83a74364eaeb1ee232 329 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 158 177 1.7E-58 T 06-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 BWK49_RS25250 a9954755be3f0d83a74364eaeb1ee232 329 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 272 287 1.7E-58 T 06-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 BWK49_RS25250 a9954755be3f0d83a74364eaeb1ee232 329 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 247 263 1.7E-58 T 06-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 BWK49_RS25250 a9954755be3f0d83a74364eaeb1ee232 329 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 196 215 1.7E-58 T 06-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 BWK49_RS25250 a9954755be3f0d83a74364eaeb1ee232 329 SMART SM01004 6 328 2.0E-205 T 06-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 BWK49_RS25250 a9954755be3f0d83a74364eaeb1ee232 329 Pfam PF00490 Delta-aminolevulinic acid dehydratase 9 327 9.7E-132 T 06-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 BWK49_RS25250 a9954755be3f0d83a74364eaeb1ee232 329 Gene3D G3DSA:3.20.20.70 5 329 3.1E-137 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 BWK49_RS25250 a9954755be3f0d83a74364eaeb1ee232 329 PIRSF PIRSF001415 1 329 2.2E-139 T 06-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 BWK49_RS25250 a9954755be3f0d83a74364eaeb1ee232 329 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 247 259 - T 06-07-2017 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 BWK49_RS25250 a9954755be3f0d83a74364eaeb1ee232 329 SUPERFAMILY SSF51569 6 328 2.2E-125 T 06-07-2017 BWK49_RS16135 f3bc6b3a82447124799756efdc9ed739 430 SUPERFAMILY SSF54631 276 400 3.41E-24 T 06-07-2017 BWK49_RS16135 f3bc6b3a82447124799756efdc9ed739 430 Pfam PF00571 CBS domain 341 394 7.3E-9 T 06-07-2017 IPR000644 CBS domain BWK49_RS16135 f3bc6b3a82447124799756efdc9ed739 430 Pfam PF00571 CBS domain 277 335 9.0E-5 T 06-07-2017 IPR000644 CBS domain BWK49_RS16135 f3bc6b3a82447124799756efdc9ed739 430 Gene3D G3DSA:3.10.580.10 276 394 2.1E-18 T 06-07-2017 BWK49_RS16135 f3bc6b3a82447124799756efdc9ed739 430 Gene3D G3DSA:1.25.60.10 145 270 9.2E-23 T 06-07-2017 BWK49_RS16135 f3bc6b3a82447124799756efdc9ed739 430 Pfam PF03448 MgtE intracellular N domain 172 274 1.4E-20 T 06-07-2017 IPR006668 Magnesium transporter, MgtE intracellular domain BWK49_RS16135 f3bc6b3a82447124799756efdc9ed739 430 SUPERFAMILY SSF158791 146 272 8.76E-21 T 06-07-2017 BWK49_RS16135 f3bc6b3a82447124799756efdc9ed739 430 SMART SM00116 348 396 1.0E-5 T 06-07-2017 IPR000644 CBS domain BWK49_RS16135 f3bc6b3a82447124799756efdc9ed739 430 SMART SM00116 283 337 16.0 T 06-07-2017 IPR000644 CBS domain BWK49_RS16135 f3bc6b3a82447124799756efdc9ed739 430 SMART SM00924 171 276 2.7E-23 T 06-07-2017 IPR006668 Magnesium transporter, MgtE intracellular domain BWK49_RS08905 3f1434be10d8a36ab5324196e027ceb2 622 SMART SM00382 366 551 8.1E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS08905 3f1434be10d8a36ab5324196e027ceb2 622 SUPERFAMILY SSF50249 248 323 1.7E-14 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS08905 3f1434be10d8a36ab5324196e027ceb2 622 SMART SM00357 248 309 5.3E-9 T 06-07-2017 IPR011129 Cold shock protein GO:0003676 BWK49_RS08905 3f1434be10d8a36ab5324196e027ceb2 622 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 355 559 1.5E-24 T 06-07-2017 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 BWK49_RS08905 3f1434be10d8a36ab5324196e027ceb2 622 Hamap MF_01884 Transcription termination factor Rho [rho]. 240 615 199.741 T 06-07-2017 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 BWK49_RS08905 3f1434be10d8a36ab5324196e027ceb2 622 TIGRFAM TIGR00767 rho: transcription termination factor Rho 35 614 1.1E-212 T 06-07-2017 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 BWK49_RS08905 3f1434be10d8a36ab5324196e027ceb2 622 Gene3D G3DSA:3.40.50.300 330 612 8.4E-96 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS08905 3f1434be10d8a36ab5324196e027ceb2 622 SUPERFAMILY SSF52540 317 566 3.01E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS08905 3f1434be10d8a36ab5324196e027ceb2 622 Pfam PF07497 Rho termination factor, RNA-binding domain 247 324 9.6E-28 T 06-07-2017 IPR011113 Rho termination factor, RNA-binding GO:0003723|GO:0006353 BWK49_RS08905 3f1434be10d8a36ab5324196e027ceb2 622 SMART SM00959 37 79 6.8E-13 T 06-07-2017 IPR011112 Rho termination factor, N-terminal GO:0006353 BWK49_RS08905 3f1434be10d8a36ab5324196e027ceb2 622 SUPERFAMILY SSF68912 37 77 8.24E-6 T 06-07-2017 IPR011112 Rho termination factor, N-terminal GO:0006353 BWK49_RS08905 3f1434be10d8a36ab5324196e027ceb2 622 Gene3D G3DSA:2.40.50.140 37 77 7.9E-40 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS08905 3f1434be10d8a36ab5324196e027ceb2 622 Gene3D G3DSA:2.40.50.140 242 324 7.9E-40 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS08905 3f1434be10d8a36ab5324196e027ceb2 622 Pfam PF07498 Rho termination factor, N-terminal domain 38 75 7.6E-11 T 06-07-2017 IPR011112 Rho termination factor, N-terminal GO:0006353 BWK49_RS13110 28e2fd60bf09c26fb8380c14bbb284ba 248 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 23 246 4.0E-71 T 06-07-2017 IPR003730 Multi-copper polyphenol oxidoreductase, laccase BWK49_RS13110 28e2fd60bf09c26fb8380c14bbb284ba 248 Gene3D G3DSA:3.60.140.10 17 247 2.8E-82 T 06-07-2017 IPR003730 Multi-copper polyphenol oxidoreductase, laccase BWK49_RS13110 28e2fd60bf09c26fb8380c14bbb284ba 248 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 28 248 2.0E-63 T 06-07-2017 IPR003730 Multi-copper polyphenol oxidoreductase, laccase BWK49_RS13110 28e2fd60bf09c26fb8380c14bbb284ba 248 SUPERFAMILY SSF64438 17 248 1.47E-74 T 06-07-2017 IPR011324 Cytotoxic necrotizing factor-like, catalytic BWK49_RS03555 3dda3f786376e0d0d6dca52013724c6b 516 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 2 146 7.8E-32 T 06-07-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 BWK49_RS03555 3dda3f786376e0d0d6dca52013724c6b 516 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 372 509 3.4E-28 T 06-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 BWK49_RS03555 3dda3f786376e0d0d6dca52013724c6b 516 SUPERFAMILY SSF52518 334 513 2.14E-42 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS03555 3dda3f786376e0d0d6dca52013724c6b 516 Gene3D G3DSA:3.40.50.970 2 165 1.0E-41 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS03555 3dda3f786376e0d0d6dca52013724c6b 516 SUPERFAMILY SSF52518 2 165 9.32E-38 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS03555 3dda3f786376e0d0d6dca52013724c6b 516 Gene3D G3DSA:3.40.50.970 329 512 7.9E-45 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS06990 2190c94ebaaa840d51876e1dd21854bc 282 Pfam PF00296 Luciferase-like monooxygenase 19 231 1.0E-50 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS06990 2190c94ebaaa840d51876e1dd21854bc 282 SUPERFAMILY SSF51679 18 278 4.59E-58 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS06990 2190c94ebaaa840d51876e1dd21854bc 282 TIGRFAM TIGR03619 F420_Rv2161c: probable F420-dependent oxidoreductase, Rv2161c family 18 258 1.3E-78 T 06-07-2017 IPR019921 Luciferase-like, F420-dependent oxidoreductase, Rv2161c, predicted BWK49_RS06990 2190c94ebaaa840d51876e1dd21854bc 282 Gene3D G3DSA:3.20.20.30 19 278 5.7E-61 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS29000 7bdd6fee4c937ef474f6dc611427f6c5 300 Gene3D G3DSA:3.40.50.300 51 289 2.7E-21 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS29000 7bdd6fee4c937ef474f6dc611427f6c5 300 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 52 229 7.1E-8 T 06-07-2017 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain BWK49_RS29000 7bdd6fee4c937ef474f6dc611427f6c5 300 SUPERFAMILY SSF52540 51 290 2.73E-21 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS07515 32d0554da1d0e34fc37bf0a4a6e61fa3 430 ProSitePatterns PS00164 Enolase signature. 332 345 - T 06-07-2017 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 BWK49_RS07515 32d0554da1d0e34fc37bf0a4a6e61fa3 430 SUPERFAMILY SSF54826 3 137 2.65E-51 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 BWK49_RS07515 32d0554da1d0e34fc37bf0a4a6e61fa3 430 Gene3D G3DSA:3.30.390.10 4 124 5.2E-52 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 BWK49_RS07515 32d0554da1d0e34fc37bf0a4a6e61fa3 430 SMART SM01192 138 423 2.8E-206 T 06-07-2017 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 BWK49_RS07515 32d0554da1d0e34fc37bf0a4a6e61fa3 430 SUPERFAMILY SSF51604 137 418 9.25E-122 T 06-07-2017 IPR029065 Enolase C-terminal domain-like BWK49_RS07515 32d0554da1d0e34fc37bf0a4a6e61fa3 430 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 421 5.2E-203 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 BWK49_RS07515 32d0554da1d0e34fc37bf0a4a6e61fa3 430 Hamap MF_00318 Enolase [eno]. 2 409 45.308 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 BWK49_RS07515 32d0554da1d0e34fc37bf0a4a6e61fa3 430 PRINTS PR00148 Enolase signature 309 320 2.6E-48 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 BWK49_RS07515 32d0554da1d0e34fc37bf0a4a6e61fa3 430 PRINTS PR00148 Enolase signature 160 173 2.6E-48 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 BWK49_RS07515 32d0554da1d0e34fc37bf0a4a6e61fa3 430 PRINTS PR00148 Enolase signature 37 51 2.6E-48 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 BWK49_RS07515 32d0554da1d0e34fc37bf0a4a6e61fa3 430 PRINTS PR00148 Enolase signature 106 122 2.6E-48 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 BWK49_RS07515 32d0554da1d0e34fc37bf0a4a6e61fa3 430 PRINTS PR00148 Enolase signature 332 346 2.6E-48 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 BWK49_RS07515 32d0554da1d0e34fc37bf0a4a6e61fa3 430 PRINTS PR00148 Enolase signature 361 378 2.6E-48 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 BWK49_RS07515 32d0554da1d0e34fc37bf0a4a6e61fa3 430 SMART SM01193 4 133 2.5E-87 T 06-07-2017 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 BWK49_RS07515 32d0554da1d0e34fc37bf0a4a6e61fa3 430 Gene3D G3DSA:3.20.20.120 127 421 3.2E-128 T 06-07-2017 IPR029065 Enolase C-terminal domain-like BWK49_RS07515 32d0554da1d0e34fc37bf0a4a6e61fa3 430 Pfam PF00113 Enolase, C-terminal TIM barrel domain 139 418 8.9E-126 T 06-07-2017 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 BWK49_RS07515 32d0554da1d0e34fc37bf0a4a6e61fa3 430 PIRSF PIRSF001400 2 422 8.2E-187 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 BWK49_RS07515 32d0554da1d0e34fc37bf0a4a6e61fa3 430 Pfam PF03952 Enolase, N-terminal domain 4 133 1.1E-55 T 06-07-2017 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 BWK49_RS25025 7e18c348a43a71aa6dd037c87a9eda6b 533 Gene3D G3DSA:2.30.38.10 344 414 4.7E-26 T 06-07-2017 BWK49_RS25025 7e18c348a43a71aa6dd037c87a9eda6b 533 Pfam PF00501 AMP-binding enzyme 21 423 2.1E-82 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS25025 7e18c348a43a71aa6dd037c87a9eda6b 533 SUPERFAMILY SSF56801 14 527 7.98E-129 T 06-07-2017 BWK49_RS25025 7e18c348a43a71aa6dd037c87a9eda6b 533 Pfam PF13193 AMP-binding enzyme C-terminal domain 432 514 1.9E-18 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS25025 7e18c348a43a71aa6dd037c87a9eda6b 533 Gene3D G3DSA:3.40.50.980 19 182 7.6E-17 T 06-07-2017 BWK49_RS25025 7e18c348a43a71aa6dd037c87a9eda6b 533 Gene3D G3DSA:3.30.300.30 418 524 2.5E-27 T 06-07-2017 BWK49_RS25025 7e18c348a43a71aa6dd037c87a9eda6b 533 Gene3D G3DSA:3.40.50.980 183 343 5.2E-37 T 06-07-2017 BWK49_RS25025 7e18c348a43a71aa6dd037c87a9eda6b 533 ProSitePatterns PS00455 Putative AMP-binding domain signature. 178 189 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS14400 d874d3a54f5ad58f06c430b47bcade80 231 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 69 2.8E-17 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 BWK49_RS14400 d874d3a54f5ad58f06c430b47bcade80 231 SMART SM00895 79 210 1.9E-13 T 06-07-2017 IPR011711 GntR, C-terminal BWK49_RS14400 d874d3a54f5ad58f06c430b47bcade80 231 SMART SM00345 11 69 1.2E-15 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 BWK49_RS14400 d874d3a54f5ad58f06c430b47bcade80 231 Gene3D G3DSA:1.10.10.10 7 70 1.4E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS14400 d874d3a54f5ad58f06c430b47bcade80 231 SUPERFAMILY SSF48008 76 216 9.42E-19 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal BWK49_RS14400 d874d3a54f5ad58f06c430b47bcade80 231 Gene3D G3DSA:1.20.120.530 73 221 2.7E-22 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal BWK49_RS14400 d874d3a54f5ad58f06c430b47bcade80 231 SUPERFAMILY SSF46785 8 98 1.39E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS14400 d874d3a54f5ad58f06c430b47bcade80 231 Pfam PF07729 FCD domain 81 209 8.8E-15 T 06-07-2017 IPR011711 GntR, C-terminal BWK49_RS06555 be77e5a3b4145c164404db47fce0a4ae 549 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 475 500 2.5E-35 T 06-07-2017 BWK49_RS06555 be77e5a3b4145c164404db47fce0a4ae 549 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 356 378 2.5E-35 T 06-07-2017 BWK49_RS06555 be77e5a3b4145c164404db47fce0a4ae 549 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 456 474 2.5E-35 T 06-07-2017 BWK49_RS06555 be77e5a3b4145c164404db47fce0a4ae 549 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 191 213 2.5E-35 T 06-07-2017 BWK49_RS06555 be77e5a3b4145c164404db47fce0a4ae 549 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 291 311 2.5E-35 T 06-07-2017 BWK49_RS06555 be77e5a3b4145c164404db47fce0a4ae 549 SUPERFAMILY SSF52540 144 345 6.79E-33 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS06555 be77e5a3b4145c164404db47fce0a4ae 549 Pfam PF04851 Type III restriction enzyme, res subunit 182 326 1.4E-14 T 06-07-2017 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 BWK49_RS06555 be77e5a3b4145c164404db47fce0a4ae 549 Pfam PF16203 ERCC3/RAD25/XPB C-terminal helicase 353 537 2.2E-42 T 06-07-2017 IPR032438 ERCC3/RAD25/XPB helicase, C-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 BWK49_RS06555 be77e5a3b4145c164404db47fce0a4ae 549 SMART SM00490 423 500 1.2E-9 T 06-07-2017 IPR001650 Helicase, C-terminal BWK49_RS06555 be77e5a3b4145c164404db47fce0a4ae 549 Pfam PF13625 Helicase conserved C-terminal domain 6 134 1.1E-45 T 06-07-2017 IPR032830 Helicase XPB/Ssl2, N-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 BWK49_RS06555 be77e5a3b4145c164404db47fce0a4ae 549 Gene3D G3DSA:3.40.50.300 385 512 1.2E-12 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS06555 be77e5a3b4145c164404db47fce0a4ae 549 SMART SM00487 178 353 1.9E-23 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain BWK49_RS06555 be77e5a3b4145c164404db47fce0a4ae 549 Gene3D G3DSA:3.40.50.300 180 344 4.4E-28 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS06555 be77e5a3b4145c164404db47fce0a4ae 549 SUPERFAMILY SSF52540 393 510 1.82E-26 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS06555 be77e5a3b4145c164404db47fce0a4ae 549 SUPERFAMILY SSF52540 290 360 1.82E-26 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS10170 6ff170035158e312ee0e5dd12bca14c1 562 PIRSF PIRSF005522 21 502 1.4E-221 T 06-07-2017 IPR016450 Uncharacterised conserved protein UCP005522 BWK49_RS10170 6ff170035158e312ee0e5dd12bca14c1 562 SUPERFAMILY SSF56059 344 487 8.14E-58 T 06-07-2017 BWK49_RS10170 6ff170035158e312ee0e5dd12bca14c1 562 SUPERFAMILY SSF56059 54 237 8.14E-58 T 06-07-2017 BWK49_RS10170 6ff170035158e312ee0e5dd12bca14c1 562 Pfam PF04174 A circularly permuted ATPgrasp 99 430 4.1E-164 T 06-07-2017 IPR007302 Circularly permuted ATPgrasp domain BWK49_RS24325 2039682dbe2f71ca99fea641e2b07c44 217 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 5 209 2.6E-88 T 06-07-2017 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS24325 2039682dbe2f71ca99fea641e2b07c44 217 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 3 212 39.871 T 06-07-2017 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS24325 2039682dbe2f71ca99fea641e2b07c44 217 Gene3D G3DSA:2.40.30.10 5 34 1.3E-12 T 06-07-2017 BWK49_RS24325 2039682dbe2f71ca99fea641e2b07c44 217 Gene3D G3DSA:2.40.30.10 163 214 1.3E-12 T 06-07-2017 BWK49_RS24325 2039682dbe2f71ca99fea641e2b07c44 217 Gene3D G3DSA:4.10.960.10 89 162 5.3E-35 T 06-07-2017 BWK49_RS24325 2039682dbe2f71ca99fea641e2b07c44 217 ProSitePatterns PS00474 Ribosomal protein L3 signature. 106 129 - T 06-07-2017 IPR019926 Ribosomal protein L3, conserved site BWK49_RS24325 2039682dbe2f71ca99fea641e2b07c44 217 SUPERFAMILY SSF50447 3 215 6.09E-83 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain BWK49_RS24325 2039682dbe2f71ca99fea641e2b07c44 217 Pfam PF00297 Ribosomal protein L3 92 187 5.8E-17 T 06-07-2017 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS15325 e0673446379a416d98c88179ef2595ab 591 SUPERFAMILY SSF56524 376 580 1.57E-46 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 BWK49_RS15325 e0673446379a416d98c88179ef2595ab 591 Gene3D G3DSA:3.90.420.10 394 584 1.7E-41 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 BWK49_RS15325 e0673446379a416d98c88179ef2595ab 591 SUPERFAMILY SSF81342 193 345 4.0E-17 T 06-07-2017 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 BWK49_RS15325 e0673446379a416d98c88179ef2595ab 591 SUPERFAMILY SSF81342 109 154 4.0E-17 T 06-07-2017 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 BWK49_RS15325 e0673446379a416d98c88179ef2595ab 591 Gene3D G3DSA:1.20.950.20 111 139 1.6E-15 T 06-07-2017 BWK49_RS15325 e0673446379a416d98c88179ef2595ab 591 Gene3D G3DSA:1.20.950.20 180 336 1.6E-15 T 06-07-2017 BWK49_RS15325 e0673446379a416d98c88179ef2595ab 591 Pfam PF00174 Oxidoreductase molybdopterin binding domain 427 566 2.3E-27 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 BWK49_RS15325 e0673446379a416d98c88179ef2595ab 591 Pfam PF01292 Prokaryotic cytochrome b561 112 336 3.9E-13 T 06-07-2017 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 BWK49_RS10440 ceb254ff749a8ac07a4808c3a1183f70 1662 Gene3D G3DSA:2.30.38.10 786 862 3.3E-23 T 06-07-2017 BWK49_RS10440 ceb254ff749a8ac07a4808c3a1183f70 1662 SUPERFAMILY SSF52777 213 456 2.0E-43 T 06-07-2017 BWK49_RS10440 ceb254ff749a8ac07a4808c3a1183f70 1662 Gene3D G3DSA:3.40.50.980 486 626 1.9E-48 T 06-07-2017 BWK49_RS10440 ceb254ff749a8ac07a4808c3a1183f70 1662 Gene3D G3DSA:1.10.1200.10 1549 1623 6.0E-17 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS10440 ceb254ff749a8ac07a4808c3a1183f70 1662 Gene3D G3DSA:1.10.1200.10 982 1046 9.0E-28 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS10440 ceb254ff749a8ac07a4808c3a1183f70 1662 Pfam PF13193 AMP-binding enzyme C-terminal domain 881 953 1.4E-13 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS10440 ceb254ff749a8ac07a4808c3a1183f70 1662 ProSitePatterns PS00455 Putative AMP-binding domain signature. 618 629 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS10440 ceb254ff749a8ac07a4808c3a1183f70 1662 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1579 1594 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site BWK49_RS10440 ceb254ff749a8ac07a4808c3a1183f70 1662 Gene3D G3DSA:3.40.50.980 627 785 7.0E-45 T 06-07-2017 BWK49_RS10440 ceb254ff749a8ac07a4808c3a1183f70 1662 SMART SM00823 Phosphopantetheine attachment site 978 1047 1.1E-9 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS10440 ceb254ff749a8ac07a4808c3a1183f70 1662 SMART SM00823 Phosphopantetheine attachment site 1555 1623 0.0049 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS10440 ceb254ff749a8ac07a4808c3a1183f70 1662 SUPERFAMILY SSF56801 448 989 1.44E-154 T 06-07-2017 BWK49_RS10440 ceb254ff749a8ac07a4808c3a1183f70 1662 SUPERFAMILY SSF52777 1270 1522 1.5E-44 T 06-07-2017 BWK49_RS10440 ceb254ff749a8ac07a4808c3a1183f70 1662 Pfam PF00501 AMP-binding enzyme 487 873 1.1E-93 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS10440 ceb254ff749a8ac07a4808c3a1183f70 1662 Pfam PF00550 Phosphopantetheine attachment site 1558 1619 2.5E-9 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS10440 ceb254ff749a8ac07a4808c3a1183f70 1662 Pfam PF00550 Phosphopantetheine attachment site 979 1043 3.6E-14 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS10440 ceb254ff749a8ac07a4808c3a1183f70 1662 SUPERFAMILY SSF52777 45 209 1.01E-36 T 06-07-2017 BWK49_RS10440 ceb254ff749a8ac07a4808c3a1183f70 1662 SUPERFAMILY SSF52777 1090 1260 1.89E-42 T 06-07-2017 BWK49_RS10440 ceb254ff749a8ac07a4808c3a1183f70 1662 Gene3D G3DSA:3.30.300.30 868 981 5.6E-36 T 06-07-2017 BWK49_RS10440 ceb254ff749a8ac07a4808c3a1183f70 1662 Pfam PF00668 Condensation domain 1088 1380 5.0E-52 T 06-07-2017 IPR001242 Condensation domain BWK49_RS10440 ceb254ff749a8ac07a4808c3a1183f70 1662 Pfam PF00668 Condensation domain 42 322 3.3E-45 T 06-07-2017 IPR001242 Condensation domain BWK49_RS10440 ceb254ff749a8ac07a4808c3a1183f70 1662 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1002 1017 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site BWK49_RS10440 ceb254ff749a8ac07a4808c3a1183f70 1662 SUPERFAMILY SSF47336 970 1043 5.89E-20 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS10440 ceb254ff749a8ac07a4808c3a1183f70 1662 Pfam PF13745 HxxPF-repeated domain 344 433 5.2E-6 T 06-07-2017 BWK49_RS10440 ceb254ff749a8ac07a4808c3a1183f70 1662 Pfam PF13745 HxxPF-repeated domain 1403 1496 3.4E-18 T 06-07-2017 BWK49_RS10440 ceb254ff749a8ac07a4808c3a1183f70 1662 SUPERFAMILY SSF47336 1553 1619 3.8E-12 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS10440 ceb254ff749a8ac07a4808c3a1183f70 1662 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 506 897 1.7E-127 T 06-07-2017 IPR010071 Amino acid adenylation domain BWK49_RS11040 818d28dcb95175a0f18de161023d449f 487 Gene3D G3DSA:3.30.300.30 389 484 2.1E-27 T 06-07-2017 BWK49_RS11040 818d28dcb95175a0f18de161023d449f 487 Gene3D G3DSA:3.40.50.980 22 149 9.5E-26 T 06-07-2017 BWK49_RS11040 818d28dcb95175a0f18de161023d449f 487 Pfam PF00501 AMP-binding enzyme 25 392 1.8E-58 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS11040 818d28dcb95175a0f18de161023d449f 487 Gene3D G3DSA:3.40.50.980 150 322 9.6E-26 T 06-07-2017 BWK49_RS11040 818d28dcb95175a0f18de161023d449f 487 Pfam PF13193 AMP-binding enzyme C-terminal domain 402 475 3.1E-19 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS11040 818d28dcb95175a0f18de161023d449f 487 Gene3D G3DSA:2.30.38.10 323 382 6.0E-8 T 06-07-2017 BWK49_RS11040 818d28dcb95175a0f18de161023d449f 487 SUPERFAMILY SSF56801 14 484 5.89E-104 T 06-07-2017 BWK49_RS11040 818d28dcb95175a0f18de161023d449f 487 ProSitePatterns PS00455 Putative AMP-binding domain signature. 144 155 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS21950 8f45b65b47829f6c771cd1500accd9c3 401 Gene3D G3DSA:3.30.1540.10 225 307 2.6E-31 T 06-07-2017 BWK49_RS21950 8f45b65b47829f6c771cd1500accd9c3 401 Pfam PF02515 CoA-transferase family III 7 377 4.9E-125 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 BWK49_RS21950 8f45b65b47829f6c771cd1500accd9c3 401 SUPERFAMILY SSF89796 4 400 4.45E-131 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS21950 8f45b65b47829f6c771cd1500accd9c3 401 Gene3D G3DSA:3.40.50.10540 3 218 3.6E-107 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS21950 8f45b65b47829f6c771cd1500accd9c3 401 Gene3D G3DSA:3.40.50.10540 308 401 3.6E-107 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS05810 ae407c448e8af8f81e2ef05002fdc165 420 SUPERFAMILY SSF51556 9 36 2.09E-69 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS05810 ae407c448e8af8f81e2ef05002fdc165 420 SUPERFAMILY SSF51556 67 383 2.09E-69 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS05810 ae407c448e8af8f81e2ef05002fdc165 420 Gene3D G3DSA:3.20.20.140 9 392 2.8E-66 T 06-07-2017 BWK49_RS05810 ae407c448e8af8f81e2ef05002fdc165 420 Pfam PF04909 Amidohydrolase 77 374 1.5E-20 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 BWK49_RS25090 7ba42c52c48c6565fb46f2a48cb8af0c 220 SUPERFAMILY SSF53448 7 200 1.8E-39 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases BWK49_RS25090 7ba42c52c48c6565fb46f2a48cb8af0c 220 Pfam PF00535 Glycosyl transferase family 2 9 127 3.7E-22 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 BWK49_RS25090 7ba42c52c48c6565fb46f2a48cb8af0c 220 Gene3D G3DSA:3.90.550.10 7 189 3.6E-22 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases BWK49_RS14670 6b9ddae0517909e0eeeba8917d7ba55d 143 Gene3D G3DSA:3.50.80.10 1 142 1.6E-50 T 06-07-2017 IPR023509 D-Tyr tRNAtyr deacylase-like domain BWK49_RS14670 6b9ddae0517909e0eeeba8917d7ba55d 143 SUPERFAMILY SSF69500 1 142 1.1E-43 T 06-07-2017 IPR023509 D-Tyr tRNAtyr deacylase-like domain BWK49_RS14670 6b9ddae0517909e0eeeba8917d7ba55d 143 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 2 142 6.0E-47 T 06-07-2017 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 BWK49_RS14670 6b9ddae0517909e0eeeba8917d7ba55d 143 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 1 142 1.1E-39 T 06-07-2017 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 BWK49_RS14670 6b9ddae0517909e0eeeba8917d7ba55d 143 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 143 30.682 T 06-07-2017 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 BWK49_RS02590 67328f84a7eb558dc4a2c7bbf3861b49 508 SUPERFAMILY SSF53067 7 262 9.72E-86 T 06-07-2017 BWK49_RS02590 67328f84a7eb558dc4a2c7bbf3861b49 508 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 8 259 1.0E-69 T 06-07-2017 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 BWK49_RS02590 67328f84a7eb558dc4a2c7bbf3861b49 508 Hamap MF_00186 Glycerol kinase [glpK]. 5 505 54.903 T 06-07-2017 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 BWK49_RS02590 67328f84a7eb558dc4a2c7bbf3861b49 508 SUPERFAMILY SSF53067 262 505 7.77E-82 T 06-07-2017 BWK49_RS02590 67328f84a7eb558dc4a2c7bbf3861b49 508 Gene3D G3DSA:3.30.420.40 262 505 7.9E-101 T 06-07-2017 BWK49_RS02590 67328f84a7eb558dc4a2c7bbf3861b49 508 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 370 390 - T 06-07-2017 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 BWK49_RS02590 67328f84a7eb558dc4a2c7bbf3861b49 508 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 7 504 2.0E-225 T 06-07-2017 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 BWK49_RS02590 67328f84a7eb558dc4a2c7bbf3861b49 508 Gene3D G3DSA:3.30.420.40 6 260 6.5E-100 T 06-07-2017 BWK49_RS02590 67328f84a7eb558dc4a2c7bbf3861b49 508 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 137 149 - T 06-07-2017 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 BWK49_RS02590 67328f84a7eb558dc4a2c7bbf3861b49 508 PIRSF PIRSF000538 5 508 3.5E-159 T 06-07-2017 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 BWK49_RS02590 67328f84a7eb558dc4a2c7bbf3861b49 508 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 268 458 1.3E-63 T 06-07-2017 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 BWK49_RS11430 2815d7786d9bb6e74599ea59298846ec 382 SUPERFAMILY SSF57938 133 213 1.15E-17 T 06-07-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 BWK49_RS11430 2815d7786d9bb6e74599ea59298846ec 382 Gene3D G3DSA:2.60.260.20 101 139 1.1E-16 T 06-07-2017 BWK49_RS11430 2815d7786d9bb6e74599ea59298846ec 382 Gene3D G3DSA:2.60.260.20 213 257 1.1E-16 T 06-07-2017 BWK49_RS11430 2815d7786d9bb6e74599ea59298846ec 382 SUPERFAMILY SSF49493 261 348 4.58E-21 T 06-07-2017 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 BWK49_RS11430 2815d7786d9bb6e74599ea59298846ec 382 SUPERFAMILY SSF49493 113 137 1.03E-15 T 06-07-2017 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 BWK49_RS11430 2815d7786d9bb6e74599ea59298846ec 382 SUPERFAMILY SSF49493 189 265 1.03E-15 T 06-07-2017 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 BWK49_RS11430 2815d7786d9bb6e74599ea59298846ec 382 Gene3D G3DSA:2.60.260.20 259 337 2.0E-21 T 06-07-2017 BWK49_RS11430 2815d7786d9bb6e74599ea59298846ec 382 Pfam PF00684 DnaJ central domain 146 210 3.4E-12 T 06-07-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 BWK49_RS11430 2815d7786d9bb6e74599ea59298846ec 382 PRINTS PR00625 DnaJ domain signature 24 39 9.0E-23 T 06-07-2017 IPR001623 DnaJ domain BWK49_RS11430 2815d7786d9bb6e74599ea59298846ec 382 PRINTS PR00625 DnaJ domain signature 6 24 9.0E-23 T 06-07-2017 IPR001623 DnaJ domain BWK49_RS11430 2815d7786d9bb6e74599ea59298846ec 382 PRINTS PR00625 DnaJ domain signature 60 79 9.0E-23 T 06-07-2017 IPR001623 DnaJ domain BWK49_RS11430 2815d7786d9bb6e74599ea59298846ec 382 PRINTS PR00625 DnaJ domain signature 40 60 9.0E-23 T 06-07-2017 IPR001623 DnaJ domain BWK49_RS11430 2815d7786d9bb6e74599ea59298846ec 382 Gene3D G3DSA:2.10.230.10 140 212 2.4E-18 T 06-07-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 BWK49_RS11430 2815d7786d9bb6e74599ea59298846ec 382 Pfam PF00226 DnaJ domain 4 65 2.1E-24 T 06-07-2017 IPR001623 DnaJ domain BWK49_RS11430 2815d7786d9bb6e74599ea59298846ec 382 SUPERFAMILY SSF46565 3 104 1.03E-32 T 06-07-2017 IPR001623 DnaJ domain BWK49_RS11430 2815d7786d9bb6e74599ea59298846ec 382 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 1 378 36.472 T 06-07-2017 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 BWK49_RS11430 2815d7786d9bb6e74599ea59298846ec 382 Pfam PF01556 DnaJ C terminal domain 122 337 7.6E-37 T 06-07-2017 IPR002939 Chaperone DnaJ, C-terminal BWK49_RS11430 2815d7786d9bb6e74599ea59298846ec 382 Gene3D G3DSA:1.10.287.110 3 100 1.0E-31 T 06-07-2017 IPR001623 DnaJ domain BWK49_RS11430 2815d7786d9bb6e74599ea59298846ec 382 SMART SM00271 3 60 3.2E-30 T 06-07-2017 IPR001623 DnaJ domain BWK49_RS18000 7c1fe69ae91faa81c9c77b48c7bcee01 981 Gene3D G3DSA:1.20.1640.10 168 365 2.6E-25 T 06-07-2017 BWK49_RS18000 7c1fe69ae91faa81c9c77b48c7bcee01 981 Gene3D G3DSA:1.20.1640.10 741 945 1.2E-24 T 06-07-2017 BWK49_RS18000 7c1fe69ae91faa81c9c77b48c7bcee01 981 Pfam PF03176 MMPL family 68 396 3.1E-99 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 BWK49_RS18000 7c1fe69ae91faa81c9c77b48c7bcee01 981 Pfam PF03176 MMPL family 624 951 4.1E-83 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 BWK49_RS18000 7c1fe69ae91faa81c9c77b48c7bcee01 981 SUPERFAMILY SSF82866 147 365 2.22E-26 T 06-07-2017 BWK49_RS18000 7c1fe69ae91faa81c9c77b48c7bcee01 981 TIGRFAM TIGR00833 actII: transport protein 35 943 3.2E-277 T 06-07-2017 IPR004707 Membrane transport protein MmpL family GO:0016021 BWK49_RS18000 7c1fe69ae91faa81c9c77b48c7bcee01 981 SUPERFAMILY SSF82866 734 943 3.79E-30 T 06-07-2017 BWK49_RS20860 3eb47e6cc383c45c7bcdaa2fa7506adb 215 Pfam PF00216 Bacterial DNA-binding protein 1 89 9.1E-27 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 BWK49_RS20860 3eb47e6cc383c45c7bcdaa2fa7506adb 215 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 2.7E-13 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 BWK49_RS20860 3eb47e6cc383c45c7bcdaa2fa7506adb 215 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 2.7E-13 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 BWK49_RS20860 3eb47e6cc383c45c7bcdaa2fa7506adb 215 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 2.7E-13 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 BWK49_RS20860 3eb47e6cc383c45c7bcdaa2fa7506adb 215 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 06-07-2017 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 BWK49_RS20860 3eb47e6cc383c45c7bcdaa2fa7506adb 215 SUPERFAMILY SSF47729 1 92 1.35E-27 T 06-07-2017 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 BWK49_RS20860 3eb47e6cc383c45c7bcdaa2fa7506adb 215 Gene3D G3DSA:4.10.520.10 1 91 2.0E-29 T 06-07-2017 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 BWK49_RS20860 3eb47e6cc383c45c7bcdaa2fa7506adb 215 SMART SM00411 1 90 1.5E-39 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 BWK49_RS06980 2139ae60eec3fbd2dc2ca8bda66bdc36 300 SUPERFAMILY SSF51735 1 133 2.34E-34 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS06980 2139ae60eec3fbd2dc2ca8bda66bdc36 300 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 245 258 - T 06-07-2017 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site BWK49_RS06980 2139ae60eec3fbd2dc2ca8bda66bdc36 300 Pfam PF02629 CoA binding domain 6 108 3.3E-24 T 06-07-2017 IPR003781 CoA-binding GO:0048037 BWK49_RS06980 2139ae60eec3fbd2dc2ca8bda66bdc36 300 PRINTS PR01798 Succinyl-CoA synthase signature 91 108 9.6E-35 T 06-07-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 BWK49_RS06980 2139ae60eec3fbd2dc2ca8bda66bdc36 300 PRINTS PR01798 Succinyl-CoA synthase signature 249 266 9.6E-35 T 06-07-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 BWK49_RS06980 2139ae60eec3fbd2dc2ca8bda66bdc36 300 PRINTS PR01798 Succinyl-CoA synthase signature 186 204 9.6E-35 T 06-07-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 BWK49_RS06980 2139ae60eec3fbd2dc2ca8bda66bdc36 300 PRINTS PR01798 Succinyl-CoA synthase signature 217 230 9.6E-35 T 06-07-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 BWK49_RS06980 2139ae60eec3fbd2dc2ca8bda66bdc36 300 Pfam PF00549 CoA-ligase 163 280 7.9E-15 T 06-07-2017 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 BWK49_RS06980 2139ae60eec3fbd2dc2ca8bda66bdc36 300 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 3 297 4.2E-129 T 06-07-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 BWK49_RS06980 2139ae60eec3fbd2dc2ca8bda66bdc36 300 SMART SM00881 4 109 3.3E-29 T 06-07-2017 IPR003781 CoA-binding GO:0048037 BWK49_RS06980 2139ae60eec3fbd2dc2ca8bda66bdc36 300 Gene3D G3DSA:3.40.50.261 131 296 4.3E-65 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 BWK49_RS06980 2139ae60eec3fbd2dc2ca8bda66bdc36 300 SUPERFAMILY SSF52210 134 295 7.59E-47 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 BWK49_RS06980 2139ae60eec3fbd2dc2ca8bda66bdc36 300 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 163 190 - T 06-07-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 BWK49_RS06980 2139ae60eec3fbd2dc2ca8bda66bdc36 300 PIRSF PIRSF001553 1 300 4.4E-118 T 06-07-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 BWK49_RS06980 2139ae60eec3fbd2dc2ca8bda66bdc36 300 Gene3D G3DSA:3.40.50.720 2 130 3.7E-48 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS17130 057c2c88cec250d698305c1cfce84da7 237 SUPERFAMILY SSF51206 7 127 3.07E-9 T 06-07-2017 IPR018490 Cyclic nucleotide-binding-like BWK49_RS17130 057c2c88cec250d698305c1cfce84da7 237 Gene3D G3DSA:1.10.10.10 146 217 1.7E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS17130 057c2c88cec250d698305c1cfce84da7 237 Pfam PF13545 Crp-like helix-turn-helix domain 149 216 2.1E-14 T 06-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 BWK49_RS17130 057c2c88cec250d698305c1cfce84da7 237 Gene3D G3DSA:2.60.120.10 8 138 8.3E-6 T 06-07-2017 IPR014710 RmlC-like jelly roll fold BWK49_RS17130 057c2c88cec250d698305c1cfce84da7 237 SUPERFAMILY SSF46785 147 221 5.44E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS18350 30f35963e242333ee92044af34310e18 425 Pfam PF00925 GTP cyclohydrolase II 210 381 2.0E-73 T 06-07-2017 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 BWK49_RS18350 30f35963e242333ee92044af34310e18 425 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 5 202 1.4E-71 T 06-07-2017 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 BWK49_RS18350 30f35963e242333ee92044af34310e18 425 SUPERFAMILY SSF142695 207 384 9.42E-69 T 06-07-2017 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 BWK49_RS18350 30f35963e242333ee92044af34310e18 425 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 207 407 40.101 T 06-07-2017 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 BWK49_RS18350 30f35963e242333ee92044af34310e18 425 PIRSF PIRSF001259 2 413 5.3E-176 T 06-07-2017 BWK49_RS18350 30f35963e242333ee92044af34310e18 425 Gene3D G3DSA:3.90.870.10 2 214 3.3E-94 T 06-07-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain BWK49_RS18350 30f35963e242333ee92044af34310e18 425 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 8 200 1.4E-83 T 06-07-2017 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 BWK49_RS18350 30f35963e242333ee92044af34310e18 425 Hamap MF_01283 Riboflavin biosynthesis protein RibBA [ribBA]. 3 403 57.213 T 06-07-2017 IPR016299 Riboflavin biosynthesis protein RibBA GO:0009231 KEGG: 00740+3.5.4.25+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7539 BWK49_RS18350 30f35963e242333ee92044af34310e18 425 SUPERFAMILY SSF55821 5 208 4.12E-81 T 06-07-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain BWK49_RS18350 30f35963e242333ee92044af34310e18 425 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 2 206 37.461 T 06-07-2017 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 BWK49_RS18350 30f35963e242333ee92044af34310e18 425 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 211 404 7.3E-74 T 06-07-2017 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 BWK49_RS06940 9544962f1139cab95e8df2e467831743 287 Gene3D G3DSA:1.10.8.50 140 272 8.9E-34 T 06-07-2017 BWK49_RS06940 9544962f1139cab95e8df2e467831743 287 SUPERFAMILY SSF81624 2 145 2.69E-22 T 06-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 BWK49_RS06940 9544962f1139cab95e8df2e467831743 287 SUPERFAMILY SSF46946 139 219 1.44E-21 T 06-07-2017 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 BWK49_RS06940 9544962f1139cab95e8df2e467831743 287 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 141 220 1.1E-17 T 06-07-2017 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 BWK49_RS06940 9544962f1139cab95e8df2e467831743 287 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 2 85 4.6E-12 T 06-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 BWK49_RS06940 9544962f1139cab95e8df2e467831743 287 SUPERFAMILY SSF57716 228 272 5.99E-11 T 06-07-2017 BWK49_RS06940 9544962f1139cab95e8df2e467831743 287 SMART SM01232 139 229 3.1E-27 T 06-07-2017 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 BWK49_RS06940 9544962f1139cab95e8df2e467831743 287 Gene3D G3DSA:3.20.190.10 2 139 5.2E-17 T 06-07-2017 BWK49_RS06940 9544962f1139cab95e8df2e467831743 287 SMART SM00898 2 125 9.6E-24 T 06-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 BWK49_RS06940 9544962f1139cab95e8df2e467831743 287 Pfam PF06827 Zinc finger found in FPG and IleRS 244 271 2.1E-7 T 06-07-2017 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 BWK49_RS23115 6c2b69faa5ac88352e8b71329778aa95 146 SMART SM00448 8 130 1.8E-25 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 BWK49_RS23115 6c2b69faa5ac88352e8b71329778aa95 146 Gene3D G3DSA:3.40.50.2300 5 133 1.5E-35 T 06-07-2017 BWK49_RS23115 6c2b69faa5ac88352e8b71329778aa95 146 Pfam PF00072 Response regulator receiver domain 10 131 3.2E-21 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 BWK49_RS23115 6c2b69faa5ac88352e8b71329778aa95 146 SUPERFAMILY SSF52172 8 134 1.85E-32 T 06-07-2017 IPR011006 CheY-like superfamily BWK49_RS01315 e3fd47bf5bbe2f36352ce58904d6f12b 412 SUPERFAMILY SSF56601 33 398 4.65E-64 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like BWK49_RS01315 e3fd47bf5bbe2f36352ce58904d6f12b 412 Gene3D G3DSA:3.40.710.10 29 405 2.5E-59 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like BWK49_RS01315 e3fd47bf5bbe2f36352ce58904d6f12b 412 Pfam PF00144 Beta-lactamase 49 400 8.1E-63 T 06-07-2017 IPR001466 Beta-lactamase-related BWK49_RS12925 b31736ea84c4f92112bf356909b63687 383 Pfam PF00877 NlpC/P60 family 283 368 5.1E-24 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain BWK49_RS12925 b31736ea84c4f92112bf356909b63687 383 SUPERFAMILY SSF54001 269 382 1.11E-36 T 06-07-2017 BWK49_RS12925 b31736ea84c4f92112bf356909b63687 383 Gene3D G3DSA:3.90.1720.10 270 382 1.1E-39 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain BWK49_RS11525 230ed0bc34db24979afd48ef995ffbef 205 Gene3D G3DSA:2.60.40.200 64 203 2.6E-30 T 06-07-2017 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 BWK49_RS11525 230ed0bc34db24979afd48ef995ffbef 205 SUPERFAMILY SSF49329 64 203 1.83E-32 T 06-07-2017 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 BWK49_RS11525 230ed0bc34db24979afd48ef995ffbef 205 Pfam PF00080 Copper/zinc superoxide dismutase (SODC) 71 202 4.4E-22 T 06-07-2017 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 BWK49_RS16160 625c4427d0aca71da7ac179a8ebc2361 218 SUPERFAMILY SSF53335 32 209 1.86E-45 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS16160 625c4427d0aca71da7ac179a8ebc2361 218 Pfam PF13649 Methyltransferase domain 58 152 8.8E-30 T 06-07-2017 BWK49_RS16160 625c4427d0aca71da7ac179a8ebc2361 218 Gene3D G3DSA:3.40.50.150 31 201 5.5E-47 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS16040 f837e75774c3a085980137f373fe7f88 145 Gene3D G3DSA:1.10.10.60 9 100 1.4E-7 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS16040 f837e75774c3a085980137f373fe7f88 145 SUPERFAMILY SSF46689 4 102 1.43E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS16040 f837e75774c3a085980137f373fe7f88 145 Pfam PF01527 Transposase 2 84 7.5E-11 T 06-07-2017 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 BWK49_RS06875 deb1c451916557dde1d363074b2968a1 332 Gene3D G3DSA:1.10.3720.10 43 325 3.1E-34 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS06875 deb1c451916557dde1d363074b2968a1 332 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 31 326 1.4E-87 T 06-07-2017 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 BWK49_RS06875 deb1c451916557dde1d363074b2968a1 332 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 326 6.4E-16 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS06875 deb1c451916557dde1d363074b2968a1 332 SUPERFAMILY SSF161098 53 322 5.23E-31 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS24425 f37e732687f54a0ace3b1bc953a98b82 701 Hamap MF_00054_B Elongation factor G [fusA]. 9 698 109.365 T 06-07-2017 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 BWK49_RS24425 f37e732687f54a0ace3b1bc953a98b82 701 TIGRFAM TIGR00484 EF-G: translation elongation factor G 8 698 0.0 T 06-07-2017 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 BWK49_RS24425 f37e732687f54a0ace3b1bc953a98b82 701 Gene3D G3DSA:3.30.70.870 409 484 2.8E-37 T 06-07-2017 BWK49_RS24425 f37e732687f54a0ace3b1bc953a98b82 701 SMART SM00889 484 605 2.8E-68 T 06-07-2017 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 BWK49_RS24425 f37e732687f54a0ace3b1bc953a98b82 701 SUPERFAMILY SSF54980 406 484 9.71E-25 T 06-07-2017 IPR009022 Elongation factor G, III-V domain BWK49_RS24425 f37e732687f54a0ace3b1bc953a98b82 701 Gene3D G3DSA:3.30.70.240 605 697 1.4E-33 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain BWK49_RS24425 f37e732687f54a0ace3b1bc953a98b82 701 SUPERFAMILY SSF54980 610 696 1.63E-30 T 06-07-2017 IPR009022 Elongation factor G, III-V domain BWK49_RS24425 f37e732687f54a0ace3b1bc953a98b82 701 SMART SM00838 607 694 9.4E-59 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain BWK49_RS24425 f37e732687f54a0ace3b1bc953a98b82 701 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 12 183 2.8E-36 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 BWK49_RS24425 f37e732687f54a0ace3b1bc953a98b82 701 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 54 69 - T 06-07-2017 IPR031157 Tr-type G domain, conserved site BWK49_RS24425 f37e732687f54a0ace3b1bc953a98b82 701 SUPERFAMILY SSF54211 483 606 7.33E-39 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold BWK49_RS24425 f37e732687f54a0ace3b1bc953a98b82 701 Gene3D G3DSA:3.30.230.10 488 604 1.9E-45 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup BWK49_RS24425 f37e732687f54a0ace3b1bc953a98b82 701 PRINTS PR00315 GTP-binding elongation factor signature 133 142 1.9E-16 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 BWK49_RS24425 f37e732687f54a0ace3b1bc953a98b82 701 PRINTS PR00315 GTP-binding elongation factor signature 97 108 1.9E-16 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 BWK49_RS24425 f37e732687f54a0ace3b1bc953a98b82 701 PRINTS PR00315 GTP-binding elongation factor signature 81 91 1.9E-16 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 BWK49_RS24425 f37e732687f54a0ace3b1bc953a98b82 701 PRINTS PR00315 GTP-binding elongation factor signature 15 28 1.9E-16 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 BWK49_RS24425 f37e732687f54a0ace3b1bc953a98b82 701 PRINTS PR00315 GTP-binding elongation factor signature 61 69 1.9E-16 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 BWK49_RS24425 f37e732687f54a0ace3b1bc953a98b82 701 Pfam PF00679 Elongation factor G C-terminus 607 693 1.7E-30 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain BWK49_RS24425 f37e732687f54a0ace3b1bc953a98b82 701 Pfam PF03764 Elongation factor G, domain IV 483 605 1.2E-45 T 06-07-2017 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 BWK49_RS24425 f37e732687f54a0ace3b1bc953a98b82 701 SUPERFAMILY SSF50447 268 408 3.03E-33 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain BWK49_RS24425 f37e732687f54a0ace3b1bc953a98b82 701 SUPERFAMILY SSF52540 9 285 1.21E-107 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS24425 f37e732687f54a0ace3b1bc953a98b82 701 Pfam PF14492 Elongation Factor G, domain II 408 482 1.4E-33 T 06-07-2017 IPR009022 Elongation factor G, III-V domain BWK49_RS24425 f37e732687f54a0ace3b1bc953a98b82 701 Pfam PF00009 Elongation factor Tu GTP binding domain 12 285 2.5E-69 T 06-07-2017 BWK49_RS24425 f37e732687f54a0ace3b1bc953a98b82 701 Gene3D G3DSA:2.40.30.10 310 408 5.0E-35 T 06-07-2017 BWK49_RS24425 f37e732687f54a0ace3b1bc953a98b82 701 Pfam PF03144 Elongation factor Tu domain 2 328 394 2.3E-13 T 06-07-2017 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 BWK49_RS24425 f37e732687f54a0ace3b1bc953a98b82 701 Gene3D G3DSA:3.40.50.300 9 290 2.2E-106 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS03845 48d4171c287c4fe75bfae7c4006cd1c1 422 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 101 292 1.1E-64 T 06-07-2017 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 BWK49_RS03845 48d4171c287c4fe75bfae7c4006cd1c1 422 SUPERFAMILY SSF52440 2 101 2.3E-30 T 06-07-2017 IPR016185 Pre-ATP-grasp domain BWK49_RS03845 48d4171c287c4fe75bfae7c4006cd1c1 422 SUPERFAMILY SSF51246 325 413 5.81E-23 T 06-07-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 BWK49_RS03845 48d4171c287c4fe75bfae7c4006cd1c1 422 Gene3D G3DSA:3.30.470.20 188 324 5.9E-54 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 BWK49_RS03845 48d4171c287c4fe75bfae7c4006cd1c1 422 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 2 100 1.4E-28 T 06-07-2017 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 BWK49_RS03845 48d4171c287c4fe75bfae7c4006cd1c1 422 SMART SM01209 101 292 1.0E-101 T 06-07-2017 BWK49_RS03845 48d4171c287c4fe75bfae7c4006cd1c1 422 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 416 38.836 T 06-07-2017 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 BWK49_RS03845 48d4171c287c4fe75bfae7c4006cd1c1 422 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 328 413 1.7E-24 T 06-07-2017 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 BWK49_RS03845 48d4171c287c4fe75bfae7c4006cd1c1 422 Gene3D G3DSA:3.30.1490.20 122 187 1.3E-11 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 BWK49_RS03845 48d4171c287c4fe75bfae7c4006cd1c1 422 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 2 414 4.0E-147 T 06-07-2017 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 BWK49_RS03845 48d4171c287c4fe75bfae7c4006cd1c1 422 SUPERFAMILY SSF56059 102 314 2.79E-50 T 06-07-2017 BWK49_RS03845 48d4171c287c4fe75bfae7c4006cd1c1 422 Gene3D G3DSA:3.40.50.20 2 92 3.3E-31 T 06-07-2017 IPR016185 Pre-ATP-grasp domain BWK49_RS03845 48d4171c287c4fe75bfae7c4006cd1c1 422 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 286 293 - T 06-07-2017 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 BWK49_RS03845 48d4171c287c4fe75bfae7c4006cd1c1 422 Gene3D G3DSA:3.90.600.10 327 414 6.9E-28 T 06-07-2017 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 BWK49_RS03845 48d4171c287c4fe75bfae7c4006cd1c1 422 SMART SM01210 327 416 4.4E-37 T 06-07-2017 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 BWK49_RS17870 26f3e5f4cda401ab9229e47b0cd869c9 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 25 42 4.0E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS17870 26f3e5f4cda401ab9229e47b0cd869c9 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 4.0E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS17870 26f3e5f4cda401ab9229e47b0cd869c9 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 4.0E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS17870 26f3e5f4cda401ab9229e47b0cd869c9 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 4.0E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS17870 26f3e5f4cda401ab9229e47b0cd869c9 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 4.0E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS17870 26f3e5f4cda401ab9229e47b0cd869c9 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 4.0E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS17870 26f3e5f4cda401ab9229e47b0cd869c9 255 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 148 176 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS17870 26f3e5f4cda401ab9229e47b0cd869c9 255 SUPERFAMILY SSF51735 24 253 4.35E-75 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS17870 26f3e5f4cda401ab9229e47b0cd869c9 255 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 33 251 3.7E-55 T 06-07-2017 BWK49_RS17870 26f3e5f4cda401ab9229e47b0cd869c9 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 88 99 8.8E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS17870 26f3e5f4cda401ab9229e47b0cd869c9 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 161 180 8.8E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS17870 26f3e5f4cda401ab9229e47b0cd869c9 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 8.8E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS17870 26f3e5f4cda401ab9229e47b0cd869c9 255 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 24 197 2.8E-6 T 06-07-2017 BWK49_RS17870 26f3e5f4cda401ab9229e47b0cd869c9 255 Gene3D G3DSA:3.40.50.720 24 252 2.5E-76 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS11070 417aeb9aa7eddb7bccc73b42ca2bc51b 277 SUPERFAMILY SSF52096 14 276 2.93E-71 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS11070 417aeb9aa7eddb7bccc73b42ca2bc51b 277 Gene3D G3DSA:3.90.226.10 11 274 1.9E-68 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS11070 417aeb9aa7eddb7bccc73b42ca2bc51b 277 Pfam PF00378 Enoyl-CoA hydratase/isomerase 18 275 8.2E-50 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 BWK49_RS16845 4304549dffd6cca4c988d1f78cec6d45 417 SUPERFAMILY SSF53474 181 250 8.58E-42 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS16845 4304549dffd6cca4c988d1f78cec6d45 417 SUPERFAMILY SSF53474 4 138 8.58E-42 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS16845 4304549dffd6cca4c988d1f78cec6d45 417 Pfam PF12146 Serine aminopeptidase, S33 47 132 7.2E-12 T 06-07-2017 IPR022742 Serine aminopeptidase, S33 BWK49_RS16845 4304549dffd6cca4c988d1f78cec6d45 417 SUPERFAMILY SSF82784 227 406 3.53E-38 T 06-07-2017 IPR003718 OsmC/Ohr family BWK49_RS16845 4304549dffd6cca4c988d1f78cec6d45 417 Gene3D G3DSA:3.40.50.1820 6 139 4.8E-35 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS16845 4304549dffd6cca4c988d1f78cec6d45 417 Gene3D G3DSA:3.40.50.1820 181 251 4.8E-35 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS16845 4304549dffd6cca4c988d1f78cec6d45 417 Pfam PF02566 OsmC-like protein 303 405 1.8E-17 T 06-07-2017 IPR003718 OsmC/Ohr family BWK49_RS16845 4304549dffd6cca4c988d1f78cec6d45 417 Gene3D G3DSA:3.30.300.20 277 407 3.3E-40 T 06-07-2017 IPR015946 K homology domain-like, alpha/beta BWK49_RS27655 b402633ca9deb64f3c4db1eb2f35553e 143 Pfam PF05423 Mycobacterium membrane protein 6 143 7.4E-47 T 06-07-2017 IPR008693 Transport accessory protein MmpS BWK49_RS22965 c8eb601ef64725b8968558e839e7ec19 505 Pfam PF13520 Amino acid permease 28 451 4.0E-55 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 BWK49_RS22965 c8eb601ef64725b8968558e839e7ec19 505 PIRSF PIRSF006060 4 497 3.4E-89 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 BWK49_RS10800 ddb55acb9995a2a4394a7e4a98cb9355 352 Gene3D G3DSA:3.40.50.720 1 159 6.0E-18 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS10800 ddb55acb9995a2a4394a7e4a98cb9355 352 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 4 101 3.2E-6 T 06-07-2017 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 BWK49_RS10800 ddb55acb9995a2a4394a7e4a98cb9355 352 SUPERFAMILY SSF51735 5 114 1.32E-7 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS08270 b34e7241449d97b492f8cb24308bf980 629 SUPERFAMILY SSF54980 420 534 6.71E-28 T 06-07-2017 IPR009022 Elongation factor G, III-V domain BWK49_RS08270 b34e7241449d97b492f8cb24308bf980 629 Pfam PF03144 Elongation factor Tu domain 2 237 310 2.7E-12 T 06-07-2017 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 BWK49_RS08270 b34e7241449d97b492f8cb24308bf980 629 Gene3D G3DSA:3.30.70.870 325 421 1.3E-31 T 06-07-2017 BWK49_RS08270 b34e7241449d97b492f8cb24308bf980 629 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 3 620 5.2E-273 T 06-07-2017 IPR006298 GTP-binding protein TypA GO:0005525 BWK49_RS08270 b34e7241449d97b492f8cb24308bf980 629 Pfam PF00009 Elongation factor Tu GTP binding domain 3 213 6.9E-50 T 06-07-2017 BWK49_RS08270 b34e7241449d97b492f8cb24308bf980 629 Gene3D G3DSA:3.30.70.240 422 502 3.2E-31 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain BWK49_RS08270 b34e7241449d97b492f8cb24308bf980 629 Pfam PF00679 Elongation factor G C-terminus 418 502 8.8E-24 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain BWK49_RS08270 b34e7241449d97b492f8cb24308bf980 629 Gene3D G3DSA:2.40.50.250 504 598 2.4E-34 T 06-07-2017 BWK49_RS08270 b34e7241449d97b492f8cb24308bf980 629 SUPERFAMILY SSF50447 198 321 2.65E-29 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain BWK49_RS08270 b34e7241449d97b492f8cb24308bf980 629 PRINTS PR00315 GTP-binding elongation factor signature 75 85 1.7E-15 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 BWK49_RS08270 b34e7241449d97b492f8cb24308bf980 629 PRINTS PR00315 GTP-binding elongation factor signature 50 58 1.7E-15 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 BWK49_RS08270 b34e7241449d97b492f8cb24308bf980 629 PRINTS PR00315 GTP-binding elongation factor signature 5 18 1.7E-15 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 BWK49_RS08270 b34e7241449d97b492f8cb24308bf980 629 PRINTS PR00315 GTP-binding elongation factor signature 91 102 1.7E-15 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 BWK49_RS08270 b34e7241449d97b492f8cb24308bf980 629 PRINTS PR00315 GTP-binding elongation factor signature 127 136 1.7E-15 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 BWK49_RS08270 b34e7241449d97b492f8cb24308bf980 629 SUPERFAMILY SSF54980 323 409 5.32E-8 T 06-07-2017 IPR009022 Elongation factor G, III-V domain BWK49_RS08270 b34e7241449d97b492f8cb24308bf980 629 SUPERFAMILY SSF52540 3 152 1.1E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS08270 b34e7241449d97b492f8cb24308bf980 629 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 4 140 7.1E-23 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 BWK49_RS08270 b34e7241449d97b492f8cb24308bf980 629 Gene3D G3DSA:2.40.30.10 223 324 6.0E-29 T 06-07-2017 BWK49_RS08270 b34e7241449d97b492f8cb24308bf980 629 SMART SM00838 417 505 0.002 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain BWK49_RS08270 b34e7241449d97b492f8cb24308bf980 629 Gene3D G3DSA:3.40.50.300 3 222 3.2E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS26890 f976afc1e10c0fe2ae4a08ab03df2a22 493 Gene3D G3DSA:3.40.50.980 9 108 5.3E-21 T 06-07-2017 BWK49_RS26890 f976afc1e10c0fe2ae4a08ab03df2a22 493 Pfam PF13193 AMP-binding enzyme C-terminal domain 395 465 1.4E-10 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS26890 f976afc1e10c0fe2ae4a08ab03df2a22 493 SUPERFAMILY SSF56801 10 485 1.44E-103 T 06-07-2017 BWK49_RS26890 f976afc1e10c0fe2ae4a08ab03df2a22 493 Gene3D G3DSA:3.40.50.980 173 296 3.4E-31 T 06-07-2017 BWK49_RS26890 f976afc1e10c0fe2ae4a08ab03df2a22 493 Gene3D G3DSA:3.30.300.30 382 482 2.7E-22 T 06-07-2017 BWK49_RS26890 f976afc1e10c0fe2ae4a08ab03df2a22 493 Pfam PF00501 AMP-binding enzyme 16 108 2.2E-16 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS26890 f976afc1e10c0fe2ae4a08ab03df2a22 493 Pfam PF00501 AMP-binding enzyme 146 386 1.9E-39 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS26890 f976afc1e10c0fe2ae4a08ab03df2a22 493 Gene3D G3DSA:2.30.38.10 306 376 5.8E-12 T 06-07-2017 BWK49_RS12955 ac874fc1ee7f85adaa5302e86ec1b76d 412 Gene3D G3DSA:3.40.50.300 3 309 1.6E-41 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS12955 ac874fc1ee7f85adaa5302e86ec1b76d 412 Pfam PF02374 Anion-transporting ATPase 3 312 1.1E-43 T 06-07-2017 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 BWK49_RS12955 ac874fc1ee7f85adaa5302e86ec1b76d 412 TIGRFAM TIGR00345 GET3_arsA_TRC40: transport-energizing ATPase, TRC40/GET3/ArsA family 3 313 1.9E-41 T 06-07-2017 IPR016300 Arsenical pump ATPase, ArsA/GET3 GO:0005524|GO:0016887 Reactome: R-HSA-381038 BWK49_RS12955 ac874fc1ee7f85adaa5302e86ec1b76d 412 SUPERFAMILY SSF52540 3 300 2.09E-34 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS03285 ee1ab925b1d670e3fc594e716ba4b581 187 SUPERFAMILY SSF50475 4 162 4.32E-47 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 BWK49_RS03285 ee1ab925b1d670e3fc594e716ba4b581 187 Pfam PF01613 Flavin reductase like domain 15 160 9.3E-36 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 BWK49_RS03285 ee1ab925b1d670e3fc594e716ba4b581 187 Gene3D G3DSA:2.30.110.10 3 157 2.9E-55 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 BWK49_RS03285 ee1ab925b1d670e3fc594e716ba4b581 187 SMART SM00903 14 159 8.4E-58 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 BWK49_RS24225 e0487fa7e8b0f756ebb864769f77ce03 226 Gene3D G3DSA:3.30.160.20 42 103 1.7E-28 T 06-07-2017 IPR014720 Double-stranded RNA-binding domain BWK49_RS24225 e0487fa7e8b0f756ebb864769f77ce03 226 Pfam PF00333 Ribosomal protein S5, N-terminal domain 45 107 1.0E-26 T 06-07-2017 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 BWK49_RS24225 e0487fa7e8b0f756ebb864769f77ce03 226 Pfam PF03719 Ribosomal protein S5, C-terminal domain 119 189 8.5E-28 T 06-07-2017 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 BWK49_RS24225 e0487fa7e8b0f756ebb864769f77ce03 226 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 195 34.463 T 06-07-2017 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 BWK49_RS24225 e0487fa7e8b0f756ebb864769f77ce03 226 SUPERFAMILY SSF54211 111 190 6.57E-24 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold BWK49_RS24225 e0487fa7e8b0f756ebb864769f77ce03 226 ProSitePatterns PS00585 Ribosomal protein S5 signature. 60 92 - T 06-07-2017 IPR018192 Ribosomal protein S5, N-terminal, conserved site BWK49_RS24225 e0487fa7e8b0f756ebb864769f77ce03 226 SUPERFAMILY SSF54768 41 108 6.49E-22 T 06-07-2017 BWK49_RS24225 e0487fa7e8b0f756ebb864769f77ce03 226 Gene3D G3DSA:3.30.230.10 110 190 1.9E-31 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup BWK49_RS24225 e0487fa7e8b0f756ebb864769f77ce03 226 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 41 195 1.2E-68 T 06-07-2017 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 BWK49_RS04510 d975c1ca3905c7a0a07004cde1ec05c4 1951 SUPERFAMILY SSF52540 591 748 2.06E-21 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS04510 d975c1ca3905c7a0a07004cde1ec05c4 1951 Gene3D G3DSA:3.40.50.300 560 770 1.3E-21 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS04510 d975c1ca3905c7a0a07004cde1ec05c4 1951 Pfam PF13604 AAA domain 594 793 2.4E-54 T 06-07-2017 BWK49_RS04510 d975c1ca3905c7a0a07004cde1ec05c4 1951 SUPERFAMILY SSF55464 1 95 1.6E-64 T 06-07-2017 BWK49_RS04510 d975c1ca3905c7a0a07004cde1ec05c4 1951 SUPERFAMILY SSF55464 187 443 1.6E-64 T 06-07-2017 BWK49_RS04510 d975c1ca3905c7a0a07004cde1ec05c4 1951 SUPERFAMILY SSF52540 811 975 1.73E-25 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS04510 d975c1ca3905c7a0a07004cde1ec05c4 1951 SUPERFAMILY SSF52540 716 776 1.73E-25 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS04510 d975c1ca3905c7a0a07004cde1ec05c4 1951 Pfam PF08751 TrwC relaxase 8 431 5.9E-86 T 06-07-2017 IPR014862 TrwC relaxase BWK49_RS25780 582cf758b1565fde43b19d7b91afcd40 211 SUPERFAMILY SSF53474 7 208 1.69E-28 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS25780 582cf758b1565fde43b19d7b91afcd40 211 Gene3D G3DSA:3.40.50.1820 20 193 4.1E-26 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS17990 1dcac6408a55e450422d07cf74ea7921 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 3.4E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS17990 1dcac6408a55e450422d07cf74ea7921 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 3.4E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS17990 1dcac6408a55e450422d07cf74ea7921 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 3.4E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS17990 1dcac6408a55e450422d07cf74ea7921 256 SUPERFAMILY SSF51735 4 253 1.03E-63 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS17990 1dcac6408a55e450422d07cf74ea7921 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 7.4E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS17990 1dcac6408a55e450422d07cf74ea7921 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 7.4E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS17990 1dcac6408a55e450422d07cf74ea7921 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 7.4E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS17990 1dcac6408a55e450422d07cf74ea7921 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 7.4E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS17990 1dcac6408a55e450422d07cf74ea7921 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 7.4E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS17990 1dcac6408a55e450422d07cf74ea7921 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 7.4E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS17990 1dcac6408a55e450422d07cf74ea7921 256 Gene3D G3DSA:3.40.50.720 2 253 6.3E-64 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS17990 1dcac6408a55e450422d07cf74ea7921 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 251 3.1E-46 T 06-07-2017 BWK49_RS16155 f7ce2730b5f25fb12e5202d52870549b 491 SUPERFAMILY SSF49503 41 163 5.96E-31 T 06-07-2017 IPR008972 Cupredoxin BWK49_RS16155 f7ce2730b5f25fb12e5202d52870549b 491 SUPERFAMILY SSF49503 167 351 7.85E-37 T 06-07-2017 IPR008972 Cupredoxin BWK49_RS16155 f7ce2730b5f25fb12e5202d52870549b 491 Pfam PF07732 Multicopper oxidase 60 163 2.2E-26 T 06-07-2017 IPR011707 Multicopper oxidase, type 3 GO:0005507 BWK49_RS16155 f7ce2730b5f25fb12e5202d52870549b 491 ProSitePatterns PS00079 Multicopper oxidases signature 1. 467 487 - T 06-07-2017 IPR033138 Multicopper oxidases, conserved site BWK49_RS16155 f7ce2730b5f25fb12e5202d52870549b 491 Gene3D G3DSA:2.60.40.420 168 353 1.0E-50 T 06-07-2017 IPR008972 Cupredoxin BWK49_RS16155 f7ce2730b5f25fb12e5202d52870549b 491 Pfam PF07731 Multicopper oxidase 377 487 1.1E-30 T 06-07-2017 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 BWK49_RS16155 f7ce2730b5f25fb12e5202d52870549b 491 Gene3D G3DSA:2.60.40.420 31 164 1.1E-29 T 06-07-2017 IPR008972 Cupredoxin BWK49_RS16155 f7ce2730b5f25fb12e5202d52870549b 491 Gene3D G3DSA:2.60.40.420 380 489 2.4E-41 T 06-07-2017 IPR008972 Cupredoxin BWK49_RS16155 f7ce2730b5f25fb12e5202d52870549b 491 ProSitePatterns PS00080 Multicopper oxidases signature 2. 472 483 - T 06-07-2017 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 BWK49_RS16155 f7ce2730b5f25fb12e5202d52870549b 491 SUPERFAMILY SSF49503 379 486 1.27E-35 T 06-07-2017 IPR008972 Cupredoxin BWK49_RS16155 f7ce2730b5f25fb12e5202d52870549b 491 Pfam PF00394 Multicopper oxidase 172 336 7.7E-25 T 06-07-2017 IPR001117 Multicopper oxidase, type 1 GO:0016491|GO:0055114 BWK49_RS24290 35847cc821fdd816a4f50d4782223612 138 SUPERFAMILY SSF54686 1 136 5.1E-55 T 06-07-2017 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 BWK49_RS24290 35847cc821fdd816a4f50d4782223612 138 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 127 2.4E-54 T 06-07-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS24290 35847cc821fdd816a4f50d4782223612 138 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 06-07-2017 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS24290 35847cc821fdd816a4f50d4782223612 138 PRINTS PR00060 Ribosomal protein L16 signature 58 87 4.5E-37 T 06-07-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS24290 35847cc821fdd816a4f50d4782223612 138 PRINTS PR00060 Ribosomal protein L16 signature 42 53 4.5E-37 T 06-07-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS24290 35847cc821fdd816a4f50d4782223612 138 PRINTS PR00060 Ribosomal protein L16 signature 88 117 4.5E-37 T 06-07-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS24290 35847cc821fdd816a4f50d4782223612 138 PRINTS PR00060 Ribosomal protein L16 signature 24 36 4.5E-37 T 06-07-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS24290 35847cc821fdd816a4f50d4782223612 138 Gene3D G3DSA:3.90.1170.10 24 136 1.3E-50 T 06-07-2017 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 BWK49_RS24290 35847cc821fdd816a4f50d4782223612 138 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 06-07-2017 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS24290 35847cc821fdd816a4f50d4782223612 138 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 37.588 T 06-07-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS24290 35847cc821fdd816a4f50d4782223612 138 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 9.3E-47 T 06-07-2017 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 BWK49_RS24685 1ec97bec01b7315591bd4da6cd643bf6 288 PIRSF PIRSF003085 2 288 6.2E-113 T 06-07-2017 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 BWK49_RS24685 1ec97bec01b7315591bd4da6cd643bf6 288 Pfam PF02353 Mycolic acid cyclopropane synthetase 5 284 2.4E-118 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS24685 1ec97bec01b7315591bd4da6cd643bf6 288 Gene3D G3DSA:3.40.50.150 6 287 8.6E-87 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS24685 1ec97bec01b7315591bd4da6cd643bf6 288 SUPERFAMILY SSF53335 13 288 1.4E-72 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS06615 f46dc24b6550d7384d9dd0853a3366b8 334 PIRSF PIRSF015753 1 305 1.8E-109 T 06-07-2017 IPR016639 Glutathione S-transferase (GST) KEGG: 00480+2.5.1.18|KEGG: 00980+2.5.1.18|KEGG: 00982+2.5.1.18|MetaCyc: PWY-4061|MetaCyc: PWY-6842|MetaCyc: PWY-7112|MetaCyc: PWY-7533 BWK49_RS06615 f46dc24b6550d7384d9dd0853a3366b8 334 SUPERFAMILY SSF47616 157 322 1.17E-35 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like BWK49_RS06615 f46dc24b6550d7384d9dd0853a3366b8 334 Pfam PF13410 Glutathione S-transferase, C-terminal domain 185 255 6.1E-12 T 06-07-2017 BWK49_RS06615 f46dc24b6550d7384d9dd0853a3366b8 334 Gene3D G3DSA:1.20.1050.10 161 270 1.2E-25 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like BWK49_RS06615 f46dc24b6550d7384d9dd0853a3366b8 334 SUPERFAMILY SSF52833 21 93 1.23E-5 T 06-07-2017 IPR012336 Thioredoxin-like fold BWK49_RS06615 f46dc24b6550d7384d9dd0853a3366b8 334 Gene3D G3DSA:3.40.30.10 19 160 7.6E-15 T 06-07-2017 IPR012336 Thioredoxin-like fold BWK49_RS06615 f46dc24b6550d7384d9dd0853a3366b8 334 Pfam PF13409 Glutathione S-transferase, N-terminal domain 44 136 8.0E-9 T 06-07-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 BWK49_RS02780 2b98ec2ecd6cebf913ccf8514b1d04bb 224 SMART SM00100 10 128 1.6E-27 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain BWK49_RS02780 2b98ec2ecd6cebf913ccf8514b1d04bb 224 Pfam PF13545 Crp-like helix-turn-helix domain 148 221 1.3E-17 T 06-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 BWK49_RS02780 2b98ec2ecd6cebf913ccf8514b1d04bb 224 SUPERFAMILY SSF51206 4 142 5.89E-36 T 06-07-2017 IPR018490 Cyclic nucleotide-binding-like BWK49_RS02780 2b98ec2ecd6cebf913ccf8514b1d04bb 224 SUPERFAMILY SSF46785 145 223 1.87E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS02780 2b98ec2ecd6cebf913ccf8514b1d04bb 224 Pfam PF00027 Cyclic nucleotide-binding domain 29 114 4.4E-23 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain BWK49_RS02780 2b98ec2ecd6cebf913ccf8514b1d04bb 224 SMART SM00419 167 215 7.1E-14 T 06-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 BWK49_RS02780 2b98ec2ecd6cebf913ccf8514b1d04bb 224 Gene3D G3DSA:2.60.120.10 2 142 1.9E-37 T 06-07-2017 IPR014710 RmlC-like jelly roll fold BWK49_RS02780 2b98ec2ecd6cebf913ccf8514b1d04bb 224 Gene3D G3DSA:1.10.10.10 144 223 4.8E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS13250 21ee0de7973a64361fbaf20d362a2553 259 Pfam PF08021 Siderophore-interacting FAD-binding domain 28 132 1.3E-13 T 06-07-2017 IPR013113 FAD-binding 9, siderophore-interacting BWK49_RS13250 21ee0de7973a64361fbaf20d362a2553 259 Gene3D G3DSA:2.40.30.10 22 131 5.0E-20 T 06-07-2017 BWK49_RS13250 21ee0de7973a64361fbaf20d362a2553 259 Gene3D G3DSA:3.40.50.80 135 256 9.1E-26 T 06-07-2017 BWK49_RS13250 21ee0de7973a64361fbaf20d362a2553 259 SUPERFAMILY SSF63380 17 136 3.58E-12 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 BWK49_RS13250 21ee0de7973a64361fbaf20d362a2553 259 Pfam PF04954 Siderophore-interacting protein 140 254 3.5E-26 T 06-07-2017 IPR007037 Siderophore-interacting protein BWK49_RS08840 49b4cf44d89714d5903cb7c6022cca52 572 SUPERFAMILY SSF51735 324 480 8.53E-25 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS08840 49b4cf44d89714d5903cb7c6022cca52 572 SUPERFAMILY SSF116726 484 549 4.05E-5 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 BWK49_RS08840 49b4cf44d89714d5903cb7c6022cca52 572 Gene3D G3DSA:1.10.287.70 207 307 7.1E-15 T 06-07-2017 BWK49_RS08840 49b4cf44d89714d5903cb7c6022cca52 572 SUPERFAMILY SSF81324 203 347 2.49E-20 T 06-07-2017 BWK49_RS08840 49b4cf44d89714d5903cb7c6022cca52 572 Pfam PF07885 Ion channel 231 307 9.2E-13 T 06-07-2017 IPR013099 Potassium channel domain BWK49_RS08840 49b4cf44d89714d5903cb7c6022cca52 572 SUPERFAMILY SSF51735 4 116 2.93E-5 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS08840 49b4cf44d89714d5903cb7c6022cca52 572 Pfam PF02254 TrkA-N domain 328 428 5.3E-19 T 06-07-2017 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 BWK49_RS08840 49b4cf44d89714d5903cb7c6022cca52 572 Gene3D G3DSA:3.40.50.720 35 117 7.1E-7 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS08840 49b4cf44d89714d5903cb7c6022cca52 572 Gene3D G3DSA:3.40.50.720 323 481 2.5E-34 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS20690 971a4dc8943b0e6ed4706362eb83a641 434 Gene3D G3DSA:1.20.1250.20 211 404 2.8E-9 T 06-07-2017 BWK49_RS20690 971a4dc8943b0e6ed4706362eb83a641 434 Gene3D G3DSA:1.20.1250.20 17 196 1.2E-23 T 06-07-2017 BWK49_RS20690 971a4dc8943b0e6ed4706362eb83a641 434 SUPERFAMILY SSF103473 17 406 4.19E-40 T 06-07-2017 IPR020846 Major facilitator superfamily domain BWK49_RS20690 971a4dc8943b0e6ed4706362eb83a641 434 Pfam PF07690 Major Facilitator Superfamily 19 364 3.2E-25 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 BWK49_RS01175 353958b5d7d97c15aa925e5f7e41448e 1775 Gene3D G3DSA:3.40.366.10 724 843 6.2E-51 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 BWK49_RS01175 353958b5d7d97c15aa925e5f7e41448e 1775 Gene3D G3DSA:3.40.366.10 916 1044 6.2E-51 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 BWK49_RS01175 353958b5d7d97c15aa925e5f7e41448e 1775 SUPERFAMILY SSF47336 21 133 3.93E-15 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS01175 353958b5d7d97c15aa925e5f7e41448e 1775 Pfam PF00550 Phosphopantetheine attachment site 28 94 3.3E-11 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS01175 353958b5d7d97c15aa925e5f7e41448e 1775 Pfam PF00550 Phosphopantetheine attachment site 1253 1295 1.2E-5 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS01175 353958b5d7d97c15aa925e5f7e41448e 1775 Gene3D G3DSA:1.10.1200.10 1245 1324 1.1E-6 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS01175 353958b5d7d97c15aa925e5f7e41448e 1775 SUPERFAMILY SSF55048 856 914 6.41E-7 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 BWK49_RS01175 353958b5d7d97c15aa925e5f7e41448e 1775 SUPERFAMILY SSF53474 1504 1760 2.09E-43 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS01175 353958b5d7d97c15aa925e5f7e41448e 1775 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 497 555 7.7E-12 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS01175 353958b5d7d97c15aa925e5f7e41448e 1775 Gene3D G3DSA:3.40.47.10 122 381 2.2E-91 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS01175 353958b5d7d97c15aa925e5f7e41448e 1775 Pfam PF00975 Thioesterase domain 1511 1618 1.9E-17 T 06-07-2017 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 BWK49_RS01175 353958b5d7d97c15aa925e5f7e41448e 1775 SMART SM00823 Phosphopantetheine attachment site 27 98 1.1E-8 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS01175 353958b5d7d97c15aa925e5f7e41448e 1775 SMART SM00823 Phosphopantetheine attachment site 1247 1302 0.001 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS01175 353958b5d7d97c15aa925e5f7e41448e 1775 Pfam PF00698 Acyl transferase domain 724 1047 1.5E-50 T 06-07-2017 IPR014043 Acyl transferase BWK49_RS01175 353958b5d7d97c15aa925e5f7e41448e 1775 SUPERFAMILY SSF53901 120 490 5.29E-92 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS01175 353958b5d7d97c15aa925e5f7e41448e 1775 SUPERFAMILY SSF53901 522 543 5.29E-92 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS01175 353958b5d7d97c15aa925e5f7e41448e 1775 SMART SM00825 Beta-ketoacyl synthase 122 547 1.5E-185 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain BWK49_RS01175 353958b5d7d97c15aa925e5f7e41448e 1775 Gene3D G3DSA:3.40.50.1820 1502 1605 1.3E-31 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS01175 353958b5d7d97c15aa925e5f7e41448e 1775 Gene3D G3DSA:3.40.50.1820 1691 1760 1.3E-31 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS01175 353958b5d7d97c15aa925e5f7e41448e 1775 Gene3D G3DSA:3.40.47.10 382 545 8.1E-60 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS01175 353958b5d7d97c15aa925e5f7e41448e 1775 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 121 369 1.4E-81 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal BWK49_RS01175 353958b5d7d97c15aa925e5f7e41448e 1775 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 726 1030 4.5E-70 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain BWK49_RS01175 353958b5d7d97c15aa925e5f7e41448e 1775 Gene3D G3DSA:1.10.1200.10 25 96 7.9E-12 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS01175 353958b5d7d97c15aa925e5f7e41448e 1775 SUPERFAMILY SSF52151 725 848 3.14E-42 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 BWK49_RS01175 353958b5d7d97c15aa925e5f7e41448e 1775 SUPERFAMILY SSF52151 917 1008 3.14E-42 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 BWK49_RS01175 353958b5d7d97c15aa925e5f7e41448e 1775 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 377 494 4.6E-44 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal BWK49_RS01175 353958b5d7d97c15aa925e5f7e41448e 1775 SUPERFAMILY SSF47336 1244 1322 2.36E-10 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS06315 e2f637393e2b6655addc8a91ae054c4e 65 PRINTS PR00352 3Fe-4S ferredoxin signature 16 26 2.5E-5 T 06-07-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 BWK49_RS06315 e2f637393e2b6655addc8a91ae054c4e 65 PRINTS PR00352 3Fe-4S ferredoxin signature 48 60 2.5E-5 T 06-07-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 BWK49_RS06315 e2f637393e2b6655addc8a91ae054c4e 65 PRINTS PR00352 3Fe-4S ferredoxin signature 5 16 2.5E-5 T 06-07-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 BWK49_RS06315 e2f637393e2b6655addc8a91ae054c4e 65 Gene3D G3DSA:3.30.70.20 2 64 1.2E-16 T 06-07-2017 BWK49_RS06315 e2f637393e2b6655addc8a91ae054c4e 65 SUPERFAMILY SSF54862 2 64 4.53E-13 T 06-07-2017 BWK49_RS06315 e2f637393e2b6655addc8a91ae054c4e 65 Pfam PF13459 4Fe-4S single cluster domain 3 62 6.6E-15 T 06-07-2017 BWK49_RS26050 19653644303c32899bc40897c82343ff 449 Gene3D G3DSA:3.40.810.20 241 448 5.0E-97 T 06-07-2017 BWK49_RS26050 19653644303c32899bc40897c82343ff 449 TIGRFAM TIGR02428 pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit 242 446 9.4E-98 T 06-07-2017 IPR012791 3-oxoacid CoA-transferase, subunit B GO:0008410 BWK49_RS26050 19653644303c32899bc40897c82343ff 449 ProSitePatterns PS01273 Coenzyme A transferases signature 1. 18 33 - T 06-07-2017 IPR004163 Coenzyme A transferase binding site GO:0008152|GO:0008410 BWK49_RS26050 19653644303c32899bc40897c82343ff 449 ProSitePatterns PS01274 Coenzyme A transferases signature 2. 281 289 - T 06-07-2017 IPR004164 Coenzyme A transferase active site GO:0008152|GO:0008410 BWK49_RS26050 19653644303c32899bc40897c82343ff 449 SMART SM00882 5 217 1.4E-86 T 06-07-2017 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 BWK49_RS26050 19653644303c32899bc40897c82343ff 449 SMART SM00882 243 440 1.6E-86 T 06-07-2017 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 BWK49_RS26050 19653644303c32899bc40897c82343ff 449 PIRSF PIRSF000858 2 449 3.2E-105 T 06-07-2017 IPR014388 3-oxoacid CoA-transferase GO:0008410|GO:0046952 BWK49_RS26050 19653644303c32899bc40897c82343ff 449 SUPERFAMILY SSF100950 240 448 4.83E-77 T 06-07-2017 BWK49_RS26050 19653644303c32899bc40897c82343ff 449 TIGRFAM TIGR02429 pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit 3 216 4.3E-79 T 06-07-2017 IPR012792 3-oxoacid CoA-transferase, subunit A GO:0008410 BWK49_RS26050 19653644303c32899bc40897c82343ff 449 SUPERFAMILY SSF100950 3 286 2.67E-92 T 06-07-2017 BWK49_RS26050 19653644303c32899bc40897c82343ff 449 Gene3D G3DSA:3.40.1080.10 3 216 3.1E-95 T 06-07-2017 BWK49_RS26050 19653644303c32899bc40897c82343ff 449 Pfam PF01144 Coenzyme A transferase 8 216 2.8E-74 T 06-07-2017 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 BWK49_RS26050 19653644303c32899bc40897c82343ff 449 Pfam PF01144 Coenzyme A transferase 244 438 1.1E-44 T 06-07-2017 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 BWK49_RS09230 f6b9a627610bfe3b69d0359adb687c51 509 ProSitePatterns PS00455 Putative AMP-binding domain signature. 167 178 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS09230 f6b9a627610bfe3b69d0359adb687c51 509 Gene3D G3DSA:2.30.38.10 330 399 3.8E-20 T 06-07-2017 BWK49_RS09230 f6b9a627610bfe3b69d0359adb687c51 509 Gene3D G3DSA:3.40.50.980 4 172 1.8E-30 T 06-07-2017 BWK49_RS09230 f6b9a627610bfe3b69d0359adb687c51 509 Pfam PF00501 AMP-binding enzyme 12 410 2.9E-75 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS09230 f6b9a627610bfe3b69d0359adb687c51 509 Gene3D G3DSA:3.30.300.30 404 505 2.6E-18 T 06-07-2017 BWK49_RS09230 f6b9a627610bfe3b69d0359adb687c51 509 Gene3D G3DSA:3.40.50.980 173 329 2.2E-22 T 06-07-2017 BWK49_RS09230 f6b9a627610bfe3b69d0359adb687c51 509 SUPERFAMILY SSF56801 3 505 3.14E-112 T 06-07-2017 BWK49_RS02495 0a5c2417c765d5a087956e8ba49c2980 203 Pfam PF13662 Toprim domain 79 175 2.6E-22 T 06-07-2017 IPR006171 Toprim domain BWK49_RS02495 0a5c2417c765d5a087956e8ba49c2980 203 TIGRFAM TIGR00615 recR: recombination protein RecR 2 200 1.5E-82 T 06-07-2017 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 BWK49_RS02495 0a5c2417c765d5a087956e8ba49c2980 203 SMART SM00493 79 168 9.4E-17 T 06-07-2017 IPR006171 Toprim domain BWK49_RS02495 0a5c2417c765d5a087956e8ba49c2980 203 Hamap MF_00017 Recombination protein RecR [recR]. 1 202 100.724 T 06-07-2017 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 BWK49_RS02495 0a5c2417c765d5a087956e8ba49c2980 203 Gene3D G3DSA:3.40.50.140 128 174 3.8E-5 T 06-07-2017 IPR006171 Toprim domain BWK49_RS02495 0a5c2417c765d5a087956e8ba49c2980 203 SMART SM00278 11 30 0.0059 T 06-07-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 BWK49_RS02495 0a5c2417c765d5a087956e8ba49c2980 203 Pfam PF02132 RecR protein 39 77 4.3E-14 T 06-07-2017 IPR023628 Recombination protein RecR, C4-type zinc finger BWK49_RS02495 0a5c2417c765d5a087956e8ba49c2980 203 ProSitePatterns PS01300 RecR protein signature. 56 77 - T 06-07-2017 IPR015967 Recombination protein RecR, conserved site GO:0006281|GO:0006310 BWK49_RS02495 0a5c2417c765d5a087956e8ba49c2980 203 SUPERFAMILY SSF111304 2 202 1.83E-68 T 06-07-2017 IPR023627 Recombination protein RecR BWK49_RS02700 9016e95052ea8b9ede9081f298c18ec9 113 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 2 100 1.2E-20 T 06-07-2017 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 BWK49_RS02700 9016e95052ea8b9ede9081f298c18ec9 113 Gene3D G3DSA:3.30.750.24 2 107 4.1E-24 T 06-07-2017 IPR002645 STAS domain BWK49_RS02700 9016e95052ea8b9ede9081f298c18ec9 113 Pfam PF01740 STAS domain 2 102 3.0E-15 T 06-07-2017 IPR002645 STAS domain BWK49_RS02700 9016e95052ea8b9ede9081f298c18ec9 113 SUPERFAMILY SSF52091 2 107 1.2E-20 T 06-07-2017 IPR002645 STAS domain BWK49_RS03335 a5f5f64033f4e29824f395379c5db925 386 Gene3D G3DSA:3.40.47.10 270 385 4.2E-53 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS03335 a5f5f64033f4e29824f395379c5db925 386 Gene3D G3DSA:3.40.47.10 159 193 4.2E-53 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS03335 a5f5f64033f4e29824f395379c5db925 386 PIRSF PIRSF000429 1 386 2.1E-113 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 BWK49_RS03335 a5f5f64033f4e29824f395379c5db925 386 Pfam PF02803 Thiolase, C-terminal domain 264 385 2.4E-43 T 06-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 BWK49_RS03335 a5f5f64033f4e29824f395379c5db925 386 SUPERFAMILY SSF53901 4 263 1.08E-63 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS03335 a5f5f64033f4e29824f395379c5db925 386 Gene3D G3DSA:3.40.47.10 194 269 3.0E-58 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS03335 a5f5f64033f4e29824f395379c5db925 386 Gene3D G3DSA:3.40.47.10 4 124 3.0E-58 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS03335 a5f5f64033f4e29824f395379c5db925 386 Pfam PF00108 Thiolase, N-terminal domain 5 255 1.6E-56 T 06-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 BWK49_RS03335 a5f5f64033f4e29824f395379c5db925 386 SUPERFAMILY SSF53901 264 385 2.14E-41 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS03335 a5f5f64033f4e29824f395379c5db925 386 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 384 1.4E-123 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 BWK49_RS03335 a5f5f64033f4e29824f395379c5db925 386 ProSitePatterns PS00737 Thiolases signature 2. 332 348 - T 06-07-2017 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 BWK49_RS21905 3494cccd4fbca6a51d4a5a74cc67862b 360 SUPERFAMILY SSF140459 2 172 1.31E-62 T 06-07-2017 BWK49_RS21905 3494cccd4fbca6a51d4a5a74cc67862b 360 Pfam PF00823 PPE family 6 161 3.7E-62 T 06-07-2017 IPR000030 PPE family BWK49_RS21905 3494cccd4fbca6a51d4a5a74cc67862b 360 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 277 356 1.7E-10 T 06-07-2017 IPR022171 PPE family, C-terminal BWK49_RS13405 bbaea15df48cc1a4dda1a8fa0859be85 502 TIGRFAM TIGR03688 pupylate_PafA2: proteasome accessory factor PafA2 2 489 3.0E-243 T 06-07-2017 IPR022366 Pup deamidase GO:0008233|GO:0016811 BWK49_RS13405 bbaea15df48cc1a4dda1a8fa0859be85 502 Pfam PF03136 Pup-ligase protein 3 458 9.2E-179 T 06-07-2017 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 BWK49_RS13405 bbaea15df48cc1a4dda1a8fa0859be85 502 PIRSF PIRSF018077 8 500 4.1E-218 T 06-07-2017 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 BWK49_RS24550 ffe72b8000da73de9f8e5c8616a220d1 440 Gene3D G3DSA:3.90.1200.10 263 306 2.1E-7 T 06-07-2017 BWK49_RS24550 ffe72b8000da73de9f8e5c8616a220d1 440 SUPERFAMILY SSF56112 182 307 2.43E-30 T 06-07-2017 IPR011009 Protein kinase-like domain BWK49_RS24550 ffe72b8000da73de9f8e5c8616a220d1 440 SUPERFAMILY SSF56112 86 148 2.43E-30 T 06-07-2017 IPR011009 Protein kinase-like domain BWK49_RS24550 ffe72b8000da73de9f8e5c8616a220d1 440 Pfam PF01636 Phosphotransferase enzyme family 265 306 3.7E-5 T 06-07-2017 IPR002575 Aminoglycoside phosphotransferase BWK49_RS24550 ffe72b8000da73de9f8e5c8616a220d1 440 Pfam PF03109 ABC1 family 102 223 3.0E-36 T 06-07-2017 IPR004147 UbiB domain BWK49_RS00490 7ae02263c8837d3d8511ed12d902cbe1 395 SUPERFAMILY SSF48264 9 393 1.96E-85 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS00490 7ae02263c8837d3d8511ed12d902cbe1 395 Pfam PF00067 Cytochrome P450 194 374 1.2E-24 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS00490 7ae02263c8837d3d8511ed12d902cbe1 395 PRINTS PR00385 P450 superfamily signature 345 356 5.3E-6 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS00490 7ae02263c8837d3d8511ed12d902cbe1 395 PRINTS PR00385 P450 superfamily signature 336 345 5.3E-6 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS00490 7ae02263c8837d3d8511ed12d902cbe1 395 PRINTS PR00385 P450 superfamily signature 234 251 5.3E-6 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS00490 7ae02263c8837d3d8511ed12d902cbe1 395 PRINTS PR00385 P450 superfamily signature 269 280 5.3E-6 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS00490 7ae02263c8837d3d8511ed12d902cbe1 395 Gene3D G3DSA:1.10.630.10 6 392 2.9E-105 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS00490 7ae02263c8837d3d8511ed12d902cbe1 395 PRINTS PR00359 B-class P450 signature 82 93 7.2E-39 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS00490 7ae02263c8837d3d8511ed12d902cbe1 395 PRINTS PR00359 B-class P450 signature 345 356 7.2E-39 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS00490 7ae02263c8837d3d8511ed12d902cbe1 395 PRINTS PR00359 B-class P450 signature 287 314 7.2E-39 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS00490 7ae02263c8837d3d8511ed12d902cbe1 395 PRINTS PR00359 B-class P450 signature 315 330 7.2E-39 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS00490 7ae02263c8837d3d8511ed12d902cbe1 395 PRINTS PR00359 B-class P450 signature 269 280 7.2E-39 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS00490 7ae02263c8837d3d8511ed12d902cbe1 395 PRINTS PR00359 B-class P450 signature 145 160 7.2E-39 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS00490 7ae02263c8837d3d8511ed12d902cbe1 395 PRINTS PR00359 B-class P450 signature 336 345 7.2E-39 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS00490 7ae02263c8837d3d8511ed12d902cbe1 395 PRINTS PR00359 B-class P450 signature 128 144 7.2E-39 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS00490 7ae02263c8837d3d8511ed12d902cbe1 395 PRINTS PR00359 B-class P450 signature 183 205 7.2E-39 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS00490 7ae02263c8837d3d8511ed12d902cbe1 395 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 338 347 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 BWK49_RS16765 d880b1c80e2b21777a058154e358fd08 599 SUPERFAMILY SSF52540 278 486 5.56E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS16765 d880b1c80e2b21777a058154e358fd08 599 Pfam PF00005 ABC transporter 22 151 3.8E-23 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 BWK49_RS16765 d880b1c80e2b21777a058154e358fd08 599 Pfam PF00005 ABC transporter 302 438 2.5E-21 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 BWK49_RS16765 d880b1c80e2b21777a058154e358fd08 599 SMART SM00382 311 482 3.7E-6 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS16765 d880b1c80e2b21777a058154e358fd08 599 SMART SM00382 29 207 7.2E-6 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS16765 d880b1c80e2b21777a058154e358fd08 599 Gene3D G3DSA:3.40.50.300 8 248 3.0E-40 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS16765 d880b1c80e2b21777a058154e358fd08 599 ProSitePatterns PS00211 ABC transporters family signature. 123 137 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 BWK49_RS16765 d880b1c80e2b21777a058154e358fd08 599 SUPERFAMILY SSF52540 4 201 1.92E-38 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS16765 d880b1c80e2b21777a058154e358fd08 599 Pfam PF12848 ABC transporter 194 251 9.8E-5 T 06-07-2017 IPR032781 ABC-transporter extension domain BWK49_RS16765 d880b1c80e2b21777a058154e358fd08 599 Gene3D G3DSA:3.40.50.300 285 498 2.3E-41 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS26350 a99fc001dbf4ade9616815de0d2bd525 662 Gene3D G3DSA:3.90.640.10 197 274 3.9E-5 T 06-07-2017 BWK49_RS26350 a99fc001dbf4ade9616815de0d2bd525 662 PRINTS PR01217 Proline rich extensin signature 465 481 1.9E-9 T 06-07-2017 BWK49_RS26350 a99fc001dbf4ade9616815de0d2bd525 662 PRINTS PR01217 Proline rich extensin signature 493 505 1.9E-9 T 06-07-2017 BWK49_RS26350 a99fc001dbf4ade9616815de0d2bd525 662 PRINTS PR01217 Proline rich extensin signature 509 530 1.9E-9 T 06-07-2017 BWK49_RS26350 a99fc001dbf4ade9616815de0d2bd525 662 SUPERFAMILY SSF53067 158 343 4.57E-28 T 06-07-2017 BWK49_RS26350 a99fc001dbf4ade9616815de0d2bd525 662 Pfam PF00012 Hsp70 protein 80 342 3.2E-17 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 BWK49_RS26350 a99fc001dbf4ade9616815de0d2bd525 662 Gene3D G3DSA:3.30.420.40 158 196 2.5E-6 T 06-07-2017 BWK49_RS26350 a99fc001dbf4ade9616815de0d2bd525 662 Gene3D G3DSA:3.30.420.40 282 319 2.5E-6 T 06-07-2017 BWK49_RS25360 4e3455a49c7f6069f0c9262772209679 227 SMART SM00862 149 225 3.1E-30 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 BWK49_RS25360 4e3455a49c7f6069f0c9262772209679 227 SMART SM00448 2 112 5.4E-43 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 BWK49_RS25360 4e3455a49c7f6069f0c9262772209679 227 SUPERFAMILY SSF46894 125 226 1.96E-32 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 BWK49_RS25360 4e3455a49c7f6069f0c9262772209679 227 Pfam PF00072 Response regulator receiver domain 4 113 9.5E-28 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 BWK49_RS25360 4e3455a49c7f6069f0c9262772209679 227 Gene3D G3DSA:1.10.10.10 128 226 4.6E-36 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS25360 4e3455a49c7f6069f0c9262772209679 227 SUPERFAMILY SSF52172 2 119 1.21E-39 T 06-07-2017 IPR011006 CheY-like superfamily BWK49_RS25360 4e3455a49c7f6069f0c9262772209679 227 Gene3D G3DSA:3.40.50.2300 2 121 3.9E-39 T 06-07-2017 BWK49_RS25360 4e3455a49c7f6069f0c9262772209679 227 Pfam PF00486 Transcriptional regulatory protein, C terminal 150 225 6.1E-28 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 BWK49_RS17605 4f8df61e338a4a0c6fc863beca150a4b 2552 SMART SM00823 Phosphopantetheine attachment site 538 606 0.016 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS17605 4f8df61e338a4a0c6fc863beca150a4b 2552 SMART SM00823 Phosphopantetheine attachment site 2031 2100 3.9E-6 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS17605 4f8df61e338a4a0c6fc863beca150a4b 2552 Gene3D G3DSA:3.40.50.980 40 193 7.2E-48 T 06-07-2017 BWK49_RS17605 4f8df61e338a4a0c6fc863beca150a4b 2552 SUPERFAMILY SSF52777 615 781 4.11E-25 T 06-07-2017 BWK49_RS17605 4f8df61e338a4a0c6fc863beca150a4b 2552 SUPERFAMILY SSF56801 1503 2043 4.19E-145 T 06-07-2017 BWK49_RS17605 4f8df61e338a4a0c6fc863beca150a4b 2552 ProSitePatterns PS00012 Phosphopantetheine attachment site. 562 577 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site BWK49_RS17605 4f8df61e338a4a0c6fc863beca150a4b 2552 Pfam PF00501 AMP-binding enzyme 1541 1926 6.3E-89 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS17605 4f8df61e338a4a0c6fc863beca150a4b 2552 Pfam PF00501 AMP-binding enzyme 46 433 9.4E-88 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS17605 4f8df61e338a4a0c6fc863beca150a4b 2552 Pfam PF00550 Phosphopantetheine attachment site 2033 2096 5.5E-15 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS17605 4f8df61e338a4a0c6fc863beca150a4b 2552 Pfam PF00550 Phosphopantetheine attachment site 541 600 1.3E-9 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS17605 4f8df61e338a4a0c6fc863beca150a4b 2552 SUPERFAMILY SSF56801 11 551 2.49E-149 T 06-07-2017 BWK49_RS17605 4f8df61e338a4a0c6fc863beca150a4b 2552 Gene3D G3DSA:3.30.300.30 1921 2034 3.9E-37 T 06-07-2017 BWK49_RS17605 4f8df61e338a4a0c6fc863beca150a4b 2552 Gene3D G3DSA:3.30.300.30 428 542 4.7E-40 T 06-07-2017 BWK49_RS17605 4f8df61e338a4a0c6fc863beca150a4b 2552 ProSitePatterns PS00455 Putative AMP-binding domain signature. 185 196 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS17605 4f8df61e338a4a0c6fc863beca150a4b 2552 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1680 1691 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS17605 4f8df61e338a4a0c6fc863beca150a4b 2552 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2055 2070 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site BWK49_RS17605 4f8df61e338a4a0c6fc863beca150a4b 2552 Pfam PF00668 Condensation domain 637 911 2.3E-24 T 06-07-2017 IPR001242 Condensation domain BWK49_RS17605 4f8df61e338a4a0c6fc863beca150a4b 2552 Pfam PF00668 Condensation domain 1089 1379 9.7E-58 T 06-07-2017 IPR001242 Condensation domain BWK49_RS17605 4f8df61e338a4a0c6fc863beca150a4b 2552 SUPERFAMILY SSF52777 1266 1509 2.22E-57 T 06-07-2017 BWK49_RS17605 4f8df61e338a4a0c6fc863beca150a4b 2552 Gene3D G3DSA:2.30.38.10 345 423 5.7E-23 T 06-07-2017 BWK49_RS17605 4f8df61e338a4a0c6fc863beca150a4b 2552 Gene3D G3DSA:2.30.38.10 1839 1916 8.7E-23 T 06-07-2017 BWK49_RS17605 4f8df61e338a4a0c6fc863beca150a4b 2552 Gene3D G3DSA:3.40.50.720 2152 2450 1.3E-28 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS17605 4f8df61e338a4a0c6fc863beca150a4b 2552 SUPERFAMILY SSF51735 2151 2458 8.16E-28 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS17605 4f8df61e338a4a0c6fc863beca150a4b 2552 Pfam PF13193 AMP-binding enzyme C-terminal domain 1934 2005 1.2E-8 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS17605 4f8df61e338a4a0c6fc863beca150a4b 2552 Pfam PF13193 AMP-binding enzyme C-terminal domain 441 512 1.4E-11 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS17605 4f8df61e338a4a0c6fc863beca150a4b 2552 Gene3D G3DSA:3.40.50.980 1536 1685 1.2E-48 T 06-07-2017 BWK49_RS17605 4f8df61e338a4a0c6fc863beca150a4b 2552 SUPERFAMILY SSF47336 2023 2096 7.59E-18 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS17605 4f8df61e338a4a0c6fc863beca150a4b 2552 SUPERFAMILY SSF52777 796 1059 2.33E-26 T 06-07-2017 BWK49_RS17605 4f8df61e338a4a0c6fc863beca150a4b 2552 Gene3D G3DSA:1.10.1200.10 543 608 1.6E-25 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS17605 4f8df61e338a4a0c6fc863beca150a4b 2552 Gene3D G3DSA:1.10.1200.10 2035 2099 8.3E-25 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS17605 4f8df61e338a4a0c6fc863beca150a4b 2552 SUPERFAMILY SSF52777 1086 1281 1.33E-41 T 06-07-2017 BWK49_RS17605 4f8df61e338a4a0c6fc863beca150a4b 2552 Gene3D G3DSA:3.40.50.980 1686 1838 4.7E-37 T 06-07-2017 BWK49_RS17605 4f8df61e338a4a0c6fc863beca150a4b 2552 Gene3D G3DSA:3.40.50.980 194 344 6.4E-40 T 06-07-2017 BWK49_RS17605 4f8df61e338a4a0c6fc863beca150a4b 2552 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 926 1082 2.5E-36 T 06-07-2017 IPR010060 Non-ribosomal peptide synthase BWK49_RS17605 4f8df61e338a4a0c6fc863beca150a4b 2552 TIGRFAM TIGR01746 Thioester-redct: thioester reductase domain 2152 2551 5.6E-97 T 06-07-2017 IPR010080 Thioester reductase-like domain BWK49_RS17605 4f8df61e338a4a0c6fc863beca150a4b 2552 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 67 457 9.1E-132 T 06-07-2017 IPR010071 Amino acid adenylation domain BWK49_RS17605 4f8df61e338a4a0c6fc863beca150a4b 2552 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1562 1950 1.7E-131 T 06-07-2017 IPR010071 Amino acid adenylation domain BWK49_RS17605 4f8df61e338a4a0c6fc863beca150a4b 2552 SUPERFAMILY SSF47336 530 600 2.36E-16 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS17605 4f8df61e338a4a0c6fc863beca150a4b 2552 Pfam PF07993 Male sterility protein 2155 2417 4.6E-58 T 06-07-2017 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 BWK49_RS22125 cf5eddcd38965bb5c7023583cf2793f0 387 Pfam PF13579 Glycosyl transferase 4-like domain 18 168 2.3E-16 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 BWK49_RS22125 cf5eddcd38965bb5c7023583cf2793f0 387 Gene3D G3DSA:3.40.50.2000 202 349 1.0E-19 T 06-07-2017 BWK49_RS22125 cf5eddcd38965bb5c7023583cf2793f0 387 Pfam PF00534 Glycosyl transferases group 1 202 349 6.0E-19 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 BWK49_RS22125 cf5eddcd38965bb5c7023583cf2793f0 387 SUPERFAMILY SSF53756 18 371 2.13E-57 T 06-07-2017 BWK49_RS11710 d2feba182ab6adbbc22d02d5b25cf9fe 467 SUPERFAMILY SSF56349 92 433 8.54E-46 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 BWK49_RS11710 d2feba182ab6adbbc22d02d5b25cf9fe 467 Gene3D G3DSA:1.10.150.130 92 192 8.3E-18 T 06-07-2017 IPR023109 Integrase/recombinase, N-terminal BWK49_RS11710 d2feba182ab6adbbc22d02d5b25cf9fe 467 Gene3D G3DSA:1.10.443.10 208 433 1.6E-28 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 BWK49_RS11710 d2feba182ab6adbbc22d02d5b25cf9fe 467 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 115 179 3.8E-6 T 06-07-2017 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 BWK49_RS11710 d2feba182ab6adbbc22d02d5b25cf9fe 467 Pfam PF00589 Phage integrase family 228 426 3.7E-8 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 BWK49_RS18425 0619ecce961fb7e5f9f94d29dad3f5a6 327 Pfam PF01037 Lrp/AsnC ligand binding domain 238 305 1.9E-11 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain BWK49_RS18425 0619ecce961fb7e5f9f94d29dad3f5a6 327 Gene3D G3DSA:1.10.10.10 1 49 1.1E-10 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS18425 0619ecce961fb7e5f9f94d29dad3f5a6 327 Gene3D G3DSA:1.10.10.10 177 218 8.5E-8 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS18425 0619ecce961fb7e5f9f94d29dad3f5a6 327 Pfam PF13404 AsnC-type helix-turn-helix domain 177 214 8.0E-8 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 BWK49_RS18425 0619ecce961fb7e5f9f94d29dad3f5a6 327 Pfam PF13404 AsnC-type helix-turn-helix domain 1 42 4.9E-11 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 BWK49_RS18425 0619ecce961fb7e5f9f94d29dad3f5a6 327 SMART SM00344 177 278 1.5E-5 T 06-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 BWK49_RS18425 0619ecce961fb7e5f9f94d29dad3f5a6 327 SMART SM00344 1 105 1.3E-5 T 06-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 BWK49_RS18425 0619ecce961fb7e5f9f94d29dad3f5a6 327 Gene3D G3DSA:3.30.70.920 236 310 2.8E-15 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain BWK49_RS18425 0619ecce961fb7e5f9f94d29dad3f5a6 327 Gene3D G3DSA:3.30.70.920 64 133 2.5E-4 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain BWK49_RS18425 0619ecce961fb7e5f9f94d29dad3f5a6 327 SUPERFAMILY SSF54909 232 311 4.83E-14 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel BWK49_RS18425 0619ecce961fb7e5f9f94d29dad3f5a6 327 SUPERFAMILY SSF46785 4 52 9.58E-7 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS13825 933fc174e92f0f35732ce538553701bc 355 Gene3D G3DSA:1.10.540.10 16 95 1.1E-7 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS13825 933fc174e92f0f35732ce538553701bc 355 Gene3D G3DSA:1.20.140.10 208 344 9.5E-5 T 06-07-2017 BWK49_RS13825 933fc174e92f0f35732ce538553701bc 355 SUPERFAMILY SSF47203 228 353 1.05E-6 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS13825 933fc174e92f0f35732ce538553701bc 355 Gene3D G3DSA:2.40.110.10 124 207 4.5E-11 T 06-07-2017 BWK49_RS13825 933fc174e92f0f35732ce538553701bc 355 SUPERFAMILY SSF56645 18 213 7.33E-24 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS22015 c14ad72d0f287d12cd38d002d4872f84 446 SMART SM00928 340 385 7.2E-24 T 06-07-2017 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS22015 c14ad72d0f287d12cd38d002d4872f84 446 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 353 364 - T 06-07-2017 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS22015 c14ad72d0f287d12cd38d002d4872f84 446 SUPERFAMILY SSF142019 14 251 2.62E-84 T 06-07-2017 BWK49_RS22015 c14ad72d0f287d12cd38d002d4872f84 446 ProSitePatterns PS00644 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. 179 194 - T 06-07-2017 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS22015 c14ad72d0f287d12cd38d002d4872f84 446 Pfam PF10531 SLBB domain 256 302 3.5E-9 T 06-07-2017 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS22015 c14ad72d0f287d12cd38d002d4872f84 446 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 56 231 1.9E-45 T 06-07-2017 IPR011538 NADH-ubiquinone oxidoreductase 51 kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS22015 c14ad72d0f287d12cd38d002d4872f84 446 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 342 425 1.4E-29 T 06-07-2017 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS22015 c14ad72d0f287d12cd38d002d4872f84 446 SUPERFAMILY SSF142984 254 335 1.02E-21 T 06-07-2017 BWK49_RS22015 c14ad72d0f287d12cd38d002d4872f84 446 TIGRFAM TIGR01959 nuoF_fam: NADH oxidoreductase (quinone), F subunit 18 426 1.8E-196 T 06-07-2017 IPR011537 NADH ubiquinone oxidoreductase, F subunit GO:0010181|GO:0016651|GO:0051287|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS22015 c14ad72d0f287d12cd38d002d4872f84 446 SUPERFAMILY SSF140490 336 435 3.14E-36 T 06-07-2017 BWK49_RS21970 ed5da1a68170d4dcc031ea8f9f95fdd1 462 Gene3D G3DSA:3.90.1200.10 132 325 2.7E-30 T 06-07-2017 BWK49_RS21970 ed5da1a68170d4dcc031ea8f9f95fdd1 462 Pfam PF01636 Phosphotransferase enzyme family 31 254 7.1E-28 T 06-07-2017 IPR002575 Aminoglycoside phosphotransferase BWK49_RS21970 ed5da1a68170d4dcc031ea8f9f95fdd1 462 SUPERFAMILY SSF56112 12 326 2.04E-45 T 06-07-2017 IPR011009 Protein kinase-like domain BWK49_RS14410 b42c4e407720df1ef119c27c0e971a68 319 Pfam PF00296 Luciferase-like monooxygenase 18 235 1.5E-50 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS14410 b42c4e407720df1ef119c27c0e971a68 319 Gene3D G3DSA:3.20.20.30 8 265 8.3E-61 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS14410 b42c4e407720df1ef119c27c0e971a68 319 SUPERFAMILY SSF51679 8 278 2.62E-57 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS13485 4706d095cd694e7ccccbfd350d8788ec 249 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS13485 4706d095cd694e7ccccbfd350d8788ec 249 Pfam PF00106 short chain dehydrogenase 9 195 4.6E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS13485 4706d095cd694e7ccccbfd350d8788ec 249 SUPERFAMILY SSF51735 9 247 1.43E-39 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS13485 4706d095cd694e7ccccbfd350d8788ec 249 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 195 0.0013 T 06-07-2017 BWK49_RS13485 4706d095cd694e7ccccbfd350d8788ec 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 3.7E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS13485 4706d095cd694e7ccccbfd350d8788ec 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 3.7E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS13485 4706d095cd694e7ccccbfd350d8788ec 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 3.7E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS13485 4706d095cd694e7ccccbfd350d8788ec 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 3.7E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS13485 4706d095cd694e7ccccbfd350d8788ec 249 Gene3D G3DSA:3.40.50.720 9 220 5.1E-35 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS18555 2c2c2203cd86f6ef7c4e00e4beefdee3 187 SMART SM00841 129 184 1.4E-34 T 06-07-2017 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 BWK49_RS18555 2c2c2203cd86f6ef7c4e00e4beefdee3 187 SMART SM01185 67 121 1.4E-25 T 06-07-2017 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 BWK49_RS18555 2c2c2203cd86f6ef7c4e00e4beefdee3 187 Hamap MF_00141 Elongation factor P [efp]. 1 185 50.187 T 06-07-2017 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 BWK49_RS18555 2c2c2203cd86f6ef7c4e00e4beefdee3 187 SUPERFAMILY SSF50104 3 63 3.61E-20 T 06-07-2017 IPR008991 Translation protein SH3-like domain BWK49_RS18555 2c2c2203cd86f6ef7c4e00e4beefdee3 187 PIRSF PIRSF005901 1 186 8.0E-67 T 06-07-2017 IPR020599 Translation elongation factor P/YeiP BWK49_RS18555 2c2c2203cd86f6ef7c4e00e4beefdee3 187 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 3 60 2.6E-26 T 06-07-2017 IPR013185 Translation elongation factor, KOW-like BWK49_RS18555 2c2c2203cd86f6ef7c4e00e4beefdee3 187 SUPERFAMILY SSF50249 129 185 4.28E-18 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS18555 2c2c2203cd86f6ef7c4e00e4beefdee3 187 Gene3D G3DSA:2.30.30.30 3 63 5.7E-32 T 06-07-2017 IPR014722 Ribosomal protein L2 domain 2 BWK49_RS18555 2c2c2203cd86f6ef7c4e00e4beefdee3 187 Pfam PF09285 Elongation factor P, C-terminal 129 184 1.9E-26 T 06-07-2017 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 BWK49_RS18555 2c2c2203cd86f6ef7c4e00e4beefdee3 187 SUPERFAMILY SSF50249 65 126 1.41E-17 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS18555 2c2c2203cd86f6ef7c4e00e4beefdee3 187 Gene3D G3DSA:2.40.50.140 65 126 2.3E-23 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS18555 2c2c2203cd86f6ef7c4e00e4beefdee3 187 Gene3D G3DSA:2.40.50.140 128 185 3.7E-29 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS18555 2c2c2203cd86f6ef7c4e00e4beefdee3 187 ProSitePatterns PS01275 Elongation factor P signature. 150 169 - T 06-07-2017 IPR013852 Translation elongation factor P/YeiP, conserved site BWK49_RS18555 2c2c2203cd86f6ef7c4e00e4beefdee3 187 TIGRFAM TIGR00038 efp: translation elongation factor P 3 185 2.9E-76 T 06-07-2017 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 BWK49_RS18555 2c2c2203cd86f6ef7c4e00e4beefdee3 187 Pfam PF01132 Elongation factor P (EF-P) OB domain 68 121 8.7E-21 T 06-07-2017 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 BWK49_RS14940 e385ee8635163fd13b413033e83830c5 367 Pfam PF03459 TOBE domain 298 361 2.5E-11 T 06-07-2017 IPR005116 Transport-associated OB, type 1 BWK49_RS14940 e385ee8635163fd13b413033e83830c5 367 SUPERFAMILY SSF50331 241 363 5.48E-14 T 06-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal BWK49_RS14940 e385ee8635163fd13b413033e83830c5 367 SUPERFAMILY SSF52540 11 240 3.08E-64 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS14940 e385ee8635163fd13b413033e83830c5 367 SMART SM00382 23 216 9.6E-16 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS14940 e385ee8635163fd13b413033e83830c5 367 Pfam PF00005 ABC transporter 16 166 2.4E-34 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 BWK49_RS14940 e385ee8635163fd13b413033e83830c5 367 Gene3D G3DSA:2.40.50.100 296 363 2.1E-15 T 06-07-2017 BWK49_RS14940 e385ee8635163fd13b413033e83830c5 367 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 BWK49_RS14940 e385ee8635163fd13b413033e83830c5 367 Gene3D G3DSA:3.40.50.300 16 236 1.4E-64 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS08320 6143c77877974aaf507b2ecbd6756fd3 787 SUPERFAMILY SSF50249 687 762 2.06E-5 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS08320 6143c77877974aaf507b2ecbd6756fd3 787 Pfam PF13520 Amino acid permease 69 456 7.1E-21 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 BWK49_RS08320 6143c77877974aaf507b2ecbd6756fd3 787 Gene3D G3DSA:2.40.50.140 686 773 1.1E-9 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS11325 5ee67cd9f6ac48b694a092f7f6b62e71 552 SMART SM00919 261 520 3.2E-102 T 06-07-2017 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 BWK49_RS11325 5ee67cd9f6ac48b694a092f7f6b62e71 552 Pfam PF03949 Malic enzyme, NAD binding domain 261 519 5.7E-88 T 06-07-2017 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 BWK49_RS11325 5ee67cd9f6ac48b694a092f7f6b62e71 552 PIRSF PIRSF000106 3 552 1.6E-201 T 06-07-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 BWK49_RS11325 5ee67cd9f6ac48b694a092f7f6b62e71 552 Pfam PF00390 Malic enzyme, N-terminal domain 71 251 2.4E-72 T 06-07-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 BWK49_RS11325 5ee67cd9f6ac48b694a092f7f6b62e71 552 PRINTS PR00072 Malic enzyme signature 232 250 1.6E-71 T 06-07-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 BWK49_RS11325 5ee67cd9f6ac48b694a092f7f6b62e71 552 PRINTS PR00072 Malic enzyme signature 77 101 1.6E-71 T 06-07-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 BWK49_RS11325 5ee67cd9f6ac48b694a092f7f6b62e71 552 PRINTS PR00072 Malic enzyme signature 397 413 1.6E-71 T 06-07-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 BWK49_RS11325 5ee67cd9f6ac48b694a092f7f6b62e71 552 PRINTS PR00072 Malic enzyme signature 173 195 1.6E-71 T 06-07-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 BWK49_RS11325 5ee67cd9f6ac48b694a092f7f6b62e71 552 PRINTS PR00072 Malic enzyme signature 137 166 1.6E-71 T 06-07-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 BWK49_RS11325 5ee67cd9f6ac48b694a092f7f6b62e71 552 PRINTS PR00072 Malic enzyme signature 288 304 1.6E-71 T 06-07-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 BWK49_RS11325 5ee67cd9f6ac48b694a092f7f6b62e71 552 PRINTS PR00072 Malic enzyme signature 257 273 1.6E-71 T 06-07-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 BWK49_RS11325 5ee67cd9f6ac48b694a092f7f6b62e71 552 SMART SM01274 71 251 1.1E-97 T 06-07-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 BWK49_RS11325 5ee67cd9f6ac48b694a092f7f6b62e71 552 Gene3D G3DSA:3.40.50.720 259 549 1.7E-94 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS11325 5ee67cd9f6ac48b694a092f7f6b62e71 552 SUPERFAMILY SSF53223 5 260 1.44E-100 T 06-07-2017 BWK49_RS11325 5ee67cd9f6ac48b694a092f7f6b62e71 552 Gene3D G3DSA:3.40.50.10380 7 258 1.1E-106 T 06-07-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 BWK49_RS11325 5ee67cd9f6ac48b694a092f7f6b62e71 552 SUPERFAMILY SSF51735 261 549 2.84E-82 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS22635 3485a73e002a9ac184807abd0ade8b18 310 ProSitePatterns PS00893 Nudix box signature. 200 221 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 BWK49_RS22635 3485a73e002a9ac184807abd0ade8b18 310 Pfam PF09296 NADH pyrophosphatase-like rudimentary NUDIX domain 47 131 6.8E-6 T 06-07-2017 IPR015375 NADH pyrophosphatase-like, N-terminal GO:0016787 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381 BWK49_RS22635 3485a73e002a9ac184807abd0ade8b18 310 SUPERFAMILY SSF55811 120 283 3.79E-41 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 BWK49_RS22635 3485a73e002a9ac184807abd0ade8b18 310 Gene3D G3DSA:3.90.79.10 130 306 4.6E-43 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 BWK49_RS22635 3485a73e002a9ac184807abd0ade8b18 310 Pfam PF09297 NADH pyrophosphatase zinc ribbon domain 134 164 4.6E-9 T 06-07-2017 IPR015376 Zinc ribbon, NADH pyrophosphatase GO:0016787|GO:0046872 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381 BWK49_RS22635 3485a73e002a9ac184807abd0ade8b18 310 Pfam PF00293 NUDIX domain 169 282 1.5E-18 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 BWK49_RS19670 2e4ee3d919e0f48f49ab9474a2fe06b4 250 SUPERFAMILY SSF69796 33 237 1.1E-62 T 06-07-2017 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 BWK49_RS19670 2e4ee3d919e0f48f49ab9474a2fe06b4 250 TIGRFAM TIGR02170 thyX: thymidylate synthase, flavin-dependent 8 230 2.5E-65 T 06-07-2017 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 BWK49_RS19670 2e4ee3d919e0f48f49ab9474a2fe06b4 250 Hamap MF_01408 Thymidylate synthase ThyX [thyX]. 7 238 28.526 T 06-07-2017 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 BWK49_RS19670 2e4ee3d919e0f48f49ab9474a2fe06b4 250 Pfam PF02511 Thymidylate synthase complementing protein 32 224 3.9E-55 T 06-07-2017 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 BWK49_RS23625 7a79c475644afd39bec18499c65d7e50 238 Gene3D G3DSA:3.40.50.1240 37 230 9.9E-33 T 06-07-2017 IPR029033 Histidine phosphatase superfamily BWK49_RS23625 7a79c475644afd39bec18499c65d7e50 238 SMART SM00855 37 191 1.1E-14 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 BWK49_RS23625 7a79c475644afd39bec18499c65d7e50 238 SUPERFAMILY SSF53254 37 231 3.53E-36 T 06-07-2017 IPR029033 Histidine phosphatase superfamily BWK49_RS23625 7a79c475644afd39bec18499c65d7e50 238 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 39 230 2.4E-29 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 BWK49_RS06040 ca97b723549168d4deb8ee7130eee228 216 SUPERFAMILY SSF48498 100 214 6.5E-6 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS06040 ca97b723549168d4deb8ee7130eee228 216 Pfam PF00440 Bacterial regulatory proteins, tetR family 34 79 5.3E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS06040 ca97b723549168d4deb8ee7130eee228 216 SUPERFAMILY SSF46689 23 105 4.1E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS06040 ca97b723549168d4deb8ee7130eee228 216 Gene3D G3DSA:1.10.357.10 22 214 1.0E-25 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS03065 67ce352073edb5b4c65099f72fc37461 129 Gene3D G3DSA:3.30.1130.10 1 119 1.2E-43 T 06-07-2017 BWK49_RS03065 67ce352073edb5b4c65099f72fc37461 129 SUPERFAMILY SSF55620 1 119 1.06E-36 T 06-07-2017 BWK49_RS03065 67ce352073edb5b4c65099f72fc37461 129 Pfam PF02152 Dihydroneopterin aldolase 5 115 2.4E-33 T 06-07-2017 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 BWK49_RS03065 67ce352073edb5b4c65099f72fc37461 129 TIGRFAM TIGR00526 folB_dom: FolB domain 2 120 7.6E-37 T 06-07-2017 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 BWK49_RS03065 67ce352073edb5b4c65099f72fc37461 129 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 3 117 5.4E-40 T 06-07-2017 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 BWK49_RS03065 67ce352073edb5b4c65099f72fc37461 129 SMART SM00905 5 117 6.0E-48 T 06-07-2017 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 BWK49_RS23390 85a1ed1279f7a096300231126a5014ad 335 Pfam PF13519 von Willebrand factor type A domain 99 189 1.3E-17 T 06-07-2017 IPR002035 von Willebrand factor, type A BWK49_RS23390 85a1ed1279f7a096300231126a5014ad 335 SUPERFAMILY SSF53300 98 297 5.7E-30 T 06-07-2017 IPR002035 von Willebrand factor, type A BWK49_RS23390 85a1ed1279f7a096300231126a5014ad 335 Pfam PF07584 Aerotolerance regulator N-terminal 13 86 1.8E-7 T 06-07-2017 IPR024163 Aerotolerance regulator, N-terminal BWK49_RS23390 85a1ed1279f7a096300231126a5014ad 335 SMART SM00327 96 298 7.2E-22 T 06-07-2017 IPR002035 von Willebrand factor, type A BWK49_RS23390 85a1ed1279f7a096300231126a5014ad 335 Gene3D G3DSA:3.40.50.410 99 298 3.8E-21 T 06-07-2017 IPR002035 von Willebrand factor, type A BWK49_RS23390 85a1ed1279f7a096300231126a5014ad 335 Hamap MF_01340 UPF0353 protein . 9 335 53.746 T 06-07-2017 IPR022933 Uncharacterised protein family UPF0353 BWK49_RS19540 cfdb4b2be88ebd25a37afb66d71e0bfa 305 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 3 295 25.313 T 06-07-2017 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 BWK49_RS19540 cfdb4b2be88ebd25a37afb66d71e0bfa 305 Gene3D G3DSA:1.10.287.890 197 279 1.3E-20 T 06-07-2017 BWK49_RS19540 cfdb4b2be88ebd25a37afb66d71e0bfa 305 Gene3D G3DSA:3.40.50.300 4 168 8.9E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS19540 cfdb4b2be88ebd25a37afb66d71e0bfa 305 Pfam PF01715 IPP transferase 36 282 2.6E-68 T 06-07-2017 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 BWK49_RS19540 cfdb4b2be88ebd25a37afb66d71e0bfa 305 SUPERFAMILY SSF52540 168 215 1.28E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS19540 cfdb4b2be88ebd25a37afb66d71e0bfa 305 SUPERFAMILY SSF52540 5 36 1.28E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS19540 cfdb4b2be88ebd25a37afb66d71e0bfa 305 SUPERFAMILY SSF52540 5 146 8.63E-14 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS19540 cfdb4b2be88ebd25a37afb66d71e0bfa 305 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 6 289 3.6E-69 T 06-07-2017 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 BWK49_RS00935 d2e13d5250d5d48283ccd4a9a67b011c 283 Gene3D G3DSA:3.20.20.30 1 251 1.8E-69 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS00935 d2e13d5250d5d48283ccd4a9a67b011c 283 Pfam PF00296 Luciferase-like monooxygenase 10 229 4.6E-50 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS00935 d2e13d5250d5d48283ccd4a9a67b011c 283 SUPERFAMILY SSF51679 2 256 4.84E-64 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS00935 d2e13d5250d5d48283ccd4a9a67b011c 283 TIGRFAM TIGR03560 F420_Rv1855c: probable F420-dependent oxidoreductase, Rv1855c family 3 227 3.3E-91 T 06-07-2017 IPR019952 F420-dependent oxidoreductase-predicted, Rv1855c BWK49_RS28040 07848d5e5076d78c38658cad12ab81bd 273 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 157 185 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS28040 07848d5e5076d78c38658cad12ab81bd 273 Gene3D G3DSA:3.40.50.720 1 269 2.5E-71 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS28040 07848d5e5076d78c38658cad12ab81bd 273 SUPERFAMILY SSF51735 3 271 5.71E-66 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS28040 07848d5e5076d78c38658cad12ab81bd 273 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 270 6.3E-44 T 06-07-2017 BWK49_RS28040 07848d5e5076d78c38658cad12ab81bd 273 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 96 107 1.1E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS28040 07848d5e5076d78c38658cad12ab81bd 273 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 170 189 1.1E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS28040 07848d5e5076d78c38658cad12ab81bd 273 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 158 1.1E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS28040 07848d5e5076d78c38658cad12ab81bd 273 TIGRFAM TIGR03971 SDR_subfam_1: SDR family mycofactocin-dependent oxidoreductase 5 270 4.5E-101 T 06-07-2017 IPR023985 Mycofactocin-dependent oxidoreductase BWK49_RS28040 07848d5e5076d78c38658cad12ab81bd 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 96 107 1.6E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS28040 07848d5e5076d78c38658cad12ab81bd 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 160 1.6E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS28040 07848d5e5076d78c38658cad12ab81bd 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 189 1.6E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS28040 07848d5e5076d78c38658cad12ab81bd 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.6E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS28040 07848d5e5076d78c38658cad12ab81bd 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 191 208 1.6E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS28040 07848d5e5076d78c38658cad12ab81bd 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 234 254 1.6E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS11935 001ea81122c5b91cdf78a90c7f6f43dd 2501 Pfam PF13191 AAA ATPase domain 451 621 6.2E-26 T 06-07-2017 BWK49_RS11935 001ea81122c5b91cdf78a90c7f6f43dd 2501 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 253 389 1.5E-11 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 BWK49_RS11935 001ea81122c5b91cdf78a90c7f6f43dd 2501 SUPERFAMILY SSF52540 443 516 1.51E-13 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS11935 001ea81122c5b91cdf78a90c7f6f43dd 2501 SUPERFAMILY SSF52540 561 701 1.51E-13 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS11935 001ea81122c5b91cdf78a90c7f6f43dd 2501 Pfam PF00486 Transcriptional regulatory protein, C terminal 24 75 3.3E-8 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 BWK49_RS11935 001ea81122c5b91cdf78a90c7f6f43dd 2501 Gene3D G3DSA:1.25.40.10 954 1010 2.0E-4 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 BWK49_RS11935 001ea81122c5b91cdf78a90c7f6f43dd 2501 Gene3D G3DSA:1.25.40.10 883 921 2.0E-4 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 BWK49_RS11935 001ea81122c5b91cdf78a90c7f6f43dd 2501 Gene3D G3DSA:1.10.10.10 11 75 5.0E-8 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS11935 001ea81122c5b91cdf78a90c7f6f43dd 2501 SUPERFAMILY SSF46894 4 85 1.73E-12 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 BWK49_RS11935 001ea81122c5b91cdf78a90c7f6f43dd 2501 SUPERFAMILY SSF55073 249 425 1.32E-42 T 06-07-2017 IPR029787 Nucleotide cyclase BWK49_RS11935 001ea81122c5b91cdf78a90c7f6f43dd 2501 Gene3D G3DSA:3.30.70.1230 250 431 6.9E-31 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 BWK49_RS11935 001ea81122c5b91cdf78a90c7f6f43dd 2501 Gene3D G3DSA:3.40.50.300 579 635 2.6E-7 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS11935 001ea81122c5b91cdf78a90c7f6f43dd 2501 Gene3D G3DSA:3.40.50.300 472 538 2.6E-7 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS11935 001ea81122c5b91cdf78a90c7f6f43dd 2501 SUPERFAMILY SSF48452 1063 1238 1.14E-8 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 BWK49_RS11935 001ea81122c5b91cdf78a90c7f6f43dd 2501 SUPERFAMILY SSF54427 2236 2348 3.1E-8 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS11935 001ea81122c5b91cdf78a90c7f6f43dd 2501 SUPERFAMILY SSF48452 89 252 1.22E-35 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 BWK49_RS11935 001ea81122c5b91cdf78a90c7f6f43dd 2501 Gene3D G3DSA:1.25.40.10 93 214 1.1E-8 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 BWK49_RS11935 001ea81122c5b91cdf78a90c7f6f43dd 2501 Pfam PF03704 Bacterial transcriptional activator domain 92 232 1.3E-36 T 06-07-2017 IPR005158 Bacterial transcriptional activator domain BWK49_RS11935 001ea81122c5b91cdf78a90c7f6f43dd 2501 SMART SM01043 92 235 5.6E-46 T 06-07-2017 IPR005158 Bacterial transcriptional activator domain BWK49_RS11935 001ea81122c5b91cdf78a90c7f6f43dd 2501 SMART SM00044 197 401 5.1E-5 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 BWK49_RS11935 001ea81122c5b91cdf78a90c7f6f43dd 2501 SMART SM00028 97 130 24.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 BWK49_RS11935 001ea81122c5b91cdf78a90c7f6f43dd 2501 SMART SM00028 974 1007 29.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 BWK49_RS11935 001ea81122c5b91cdf78a90c7f6f43dd 2501 SMART SM00028 185 218 210.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 BWK49_RS11935 001ea81122c5b91cdf78a90c7f6f43dd 2501 SMART SM00028 1167 1200 490.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 BWK49_RS11935 001ea81122c5b91cdf78a90c7f6f43dd 2501 SMART SM00028 1207 1240 36.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 BWK49_RS11935 001ea81122c5b91cdf78a90c7f6f43dd 2501 SMART SM00028 1129 1162 420.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 BWK49_RS11935 001ea81122c5b91cdf78a90c7f6f43dd 2501 Gene3D G3DSA:1.25.40.10 1051 1290 2.2E-10 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 BWK49_RS11935 001ea81122c5b91cdf78a90c7f6f43dd 2501 SMART SM00862 15 87 8.1E-10 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 BWK49_RS11935 001ea81122c5b91cdf78a90c7f6f43dd 2501 Gene3D G3DSA:3.10.450.50 2239 2352 2.0E-6 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS11935 001ea81122c5b91cdf78a90c7f6f43dd 2501 Gene3D G3DSA:3.10.450.50 1691 1784 1.8E-5 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS11935 001ea81122c5b91cdf78a90c7f6f43dd 2501 SUPERFAMILY SSF54427 1692 1771 5.85E-6 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS05185 fd3660589b9ab25a4c8deba3a6a89024 63 PRINTS PR00352 3Fe-4S ferredoxin signature 5 16 4.9E-6 T 06-07-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 BWK49_RS05185 fd3660589b9ab25a4c8deba3a6a89024 63 PRINTS PR00352 3Fe-4S ferredoxin signature 16 26 4.9E-6 T 06-07-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 BWK49_RS05185 fd3660589b9ab25a4c8deba3a6a89024 63 PRINTS PR00352 3Fe-4S ferredoxin signature 47 59 4.9E-6 T 06-07-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 BWK49_RS05185 fd3660589b9ab25a4c8deba3a6a89024 63 SUPERFAMILY SSF54862 2 61 1.13E-10 T 06-07-2017 BWK49_RS05185 fd3660589b9ab25a4c8deba3a6a89024 63 Gene3D G3DSA:3.30.70.20 1 62 9.1E-16 T 06-07-2017 BWK49_RS05185 fd3660589b9ab25a4c8deba3a6a89024 63 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 5 59 1.7E-11 T 06-07-2017 BWK49_RS07050 7c627300f15c316fcca4e20c6e13d88b 662 Pfam PF02785 Biotin carboxylase C-terminal domain 324 440 5.8E-29 T 06-07-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 BWK49_RS07050 7c627300f15c316fcca4e20c6e13d88b 662 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 133 312 2.2E-59 T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 BWK49_RS07050 7c627300f15c316fcca4e20c6e13d88b 662 SUPERFAMILY SSF51230 584 653 7.07E-21 T 06-07-2017 IPR011053 Single hybrid motif BWK49_RS07050 7c627300f15c316fcca4e20c6e13d88b 662 Gene3D G3DSA:3.40.50.20 1 127 6.2E-48 T 06-07-2017 IPR016185 Pre-ATP-grasp domain BWK49_RS07050 7c627300f15c316fcca4e20c6e13d88b 662 Pfam PF00364 Biotin-requiring enzyme 588 651 6.0E-17 T 06-07-2017 IPR000089 Biotin/lipoyl attachment BWK49_RS07050 7c627300f15c316fcca4e20c6e13d88b 662 SUPERFAMILY SSF52440 1 110 2.37E-41 T 06-07-2017 IPR016185 Pre-ATP-grasp domain BWK49_RS07050 7c627300f15c316fcca4e20c6e13d88b 662 SUPERFAMILY SSF56059 80 316 8.31E-57 T 06-07-2017 BWK49_RS07050 7c627300f15c316fcca4e20c6e13d88b 662 SUPERFAMILY SSF51246 319 442 1.2E-31 T 06-07-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 BWK49_RS07050 7c627300f15c316fcca4e20c6e13d88b 662 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 609 626 - T 06-07-2017 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 BWK49_RS07050 7c627300f15c316fcca4e20c6e13d88b 662 Gene3D G3DSA:2.40.50.100 584 653 2.1E-23 T 06-07-2017 BWK49_RS07050 7c627300f15c316fcca4e20c6e13d88b 662 SMART SM00878 324 440 1.8E-43 T 06-07-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 BWK49_RS07050 7c627300f15c316fcca4e20c6e13d88b 662 Gene3D G3DSA:3.30.470.20 194 442 2.0E-83 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 BWK49_RS07050 7c627300f15c316fcca4e20c6e13d88b 662 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 106 1.9E-39 T 06-07-2017 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 BWK49_RS07050 7c627300f15c316fcca4e20c6e13d88b 662 Gene3D G3DSA:3.30.1490.20 139 190 1.6E-19 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 BWK49_RS07050 7c627300f15c316fcca4e20c6e13d88b 662 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 276 283 - T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 BWK49_RS15005 7a186728a8e39c1e3884c72a21a76c3c 489 SUPERFAMILY SSF51735 15 188 3.12E-52 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS15005 7a186728a8e39c1e3884c72a21a76c3c 489 ProSitePatterns PS00461 6-phosphogluconate dehydrogenase signature. 265 277 - T 06-07-2017 IPR006184 6-phosphogluconate-binding site GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 BWK49_RS15005 7a186728a8e39c1e3884c72a21a76c3c 489 Gene3D G3DSA:3.40.50.720 10 191 1.4E-56 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS15005 7a186728a8e39c1e3884c72a21a76c3c 489 PIRSF PIRSF000109 10 489 1.2E-198 T 06-07-2017 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 BWK49_RS15005 7a186728a8e39c1e3884c72a21a76c3c 489 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 131 156 2.4E-82 T 06-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 BWK49_RS15005 7a186728a8e39c1e3884c72a21a76c3c 489 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 179 207 2.4E-82 T 06-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 BWK49_RS15005 7a186728a8e39c1e3884c72a21a76c3c 489 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 78 107 2.4E-82 T 06-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 BWK49_RS15005 7a186728a8e39c1e3884c72a21a76c3c 489 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 15 38 2.4E-82 T 06-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 BWK49_RS15005 7a186728a8e39c1e3884c72a21a76c3c 489 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 261 288 2.4E-82 T 06-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 BWK49_RS15005 7a186728a8e39c1e3884c72a21a76c3c 489 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 368 390 2.4E-82 T 06-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 BWK49_RS15005 7a186728a8e39c1e3884c72a21a76c3c 489 Gene3D G3DSA:1.10.1040.10 192 446 2.8E-107 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 BWK49_RS15005 7a186728a8e39c1e3884c72a21a76c3c 489 TIGRFAM TIGR00873 gnd: 6-phosphogluconate dehydrogenase (decarboxylating) 16 481 2.8E-214 T 06-07-2017 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 BWK49_RS15005 7a186728a8e39c1e3884c72a21a76c3c 489 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 16 185 5.8E-49 T 06-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 BWK49_RS15005 7a186728a8e39c1e3884c72a21a76c3c 489 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 190 480 1.3E-119 T 06-07-2017 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 BWK49_RS15005 7a186728a8e39c1e3884c72a21a76c3c 489 SUPERFAMILY SSF48179 188 484 1.21E-116 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 BWK49_RS15005 7a186728a8e39c1e3884c72a21a76c3c 489 SMART SM01350 190 481 1.3E-202 T 06-07-2017 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 BWK49_RS15005 7a186728a8e39c1e3884c72a21a76c3c 489 Gene3D G3DSA:1.20.5.320 447 487 3.3E-16 T 06-07-2017 IPR012284 6-phosphogluconate dehydrogenase, domain 3 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 BWK49_RS00265 9f2d63051777eb9dd678804eb9197fa9 969 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 231 969 2.8E-214 T 06-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 BWK49_RS00265 9f2d63051777eb9dd678804eb9197fa9 969 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 305 501 2.9E-56 T 06-07-2017 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 BWK49_RS00265 9f2d63051777eb9dd678804eb9197fa9 969 SUPERFAMILY SSF50677 325 511 1.96E-43 T 06-07-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 BWK49_RS00265 9f2d63051777eb9dd678804eb9197fa9 969 SUPERFAMILY SSF47323 780 969 2.43E-32 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 BWK49_RS00265 9f2d63051777eb9dd678804eb9197fa9 969 SUPERFAMILY SSF52374 35 184 1.44E-101 T 06-07-2017 BWK49_RS00265 9f2d63051777eb9dd678804eb9197fa9 969 SUPERFAMILY SSF52374 514 785 1.44E-101 T 06-07-2017 BWK49_RS00265 9f2d63051777eb9dd678804eb9197fa9 969 SUPERFAMILY SSF52374 232 310 1.44E-101 T 06-07-2017 BWK49_RS00265 9f2d63051777eb9dd678804eb9197fa9 969 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 80 90 - T 06-07-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 BWK49_RS00265 9f2d63051777eb9dd678804eb9197fa9 969 Pfam PF09334 tRNA synthetases class I (M) 76 182 1.1E-12 T 06-07-2017 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 BWK49_RS00265 9f2d63051777eb9dd678804eb9197fa9 969 Gene3D G3DSA:1.10.730.10 766 905 1.8E-34 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 BWK49_RS00265 9f2d63051777eb9dd678804eb9197fa9 969 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 29 969 21.508 T 06-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 BWK49_RS00265 9f2d63051777eb9dd678804eb9197fa9 969 Pfam PF08264 Anticodon-binding domain of tRNA 818 931 2.3E-12 T 06-07-2017 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 BWK49_RS00265 9f2d63051777eb9dd678804eb9197fa9 969 Gene3D G3DSA:3.90.740.10 307 522 8.3E-49 T 06-07-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 BWK49_RS00265 9f2d63051777eb9dd678804eb9197fa9 969 PRINTS PR00985 Leucyl-tRNA synthetase signature 683 693 1.7E-53 T 06-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 BWK49_RS00265 9f2d63051777eb9dd678804eb9197fa9 969 PRINTS PR00985 Leucyl-tRNA synthetase signature 650 672 1.7E-53 T 06-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 BWK49_RS00265 9f2d63051777eb9dd678804eb9197fa9 969 PRINTS PR00985 Leucyl-tRNA synthetase signature 164 181 1.7E-53 T 06-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 BWK49_RS00265 9f2d63051777eb9dd678804eb9197fa9 969 PRINTS PR00985 Leucyl-tRNA synthetase signature 598 616 1.7E-53 T 06-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 BWK49_RS00265 9f2d63051777eb9dd678804eb9197fa9 969 PRINTS PR00985 Leucyl-tRNA synthetase signature 237 253 1.7E-53 T 06-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 BWK49_RS00265 9f2d63051777eb9dd678804eb9197fa9 969 PRINTS PR00985 Leucyl-tRNA synthetase signature 270 283 1.7E-53 T 06-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 BWK49_RS00265 9f2d63051777eb9dd678804eb9197fa9 969 PRINTS PR00985 Leucyl-tRNA synthetase signature 299 318 1.7E-53 T 06-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 BWK49_RS00265 9f2d63051777eb9dd678804eb9197fa9 969 Gene3D G3DSA:3.40.50.620 736 765 2.7E-125 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold BWK49_RS00265 9f2d63051777eb9dd678804eb9197fa9 969 Gene3D G3DSA:3.40.50.620 231 306 2.7E-125 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold BWK49_RS00265 9f2d63051777eb9dd678804eb9197fa9 969 Gene3D G3DSA:3.40.50.620 523 699 2.7E-125 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold BWK49_RS00265 9f2d63051777eb9dd678804eb9197fa9 969 Gene3D G3DSA:3.40.50.620 34 183 2.7E-125 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold BWK49_RS26085 38958c1c33b8d51bbc7a8dbab289c1a5 427 SUPERFAMILY SSF47203 223 385 9.5E-35 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS26085 38958c1c33b8d51bbc7a8dbab289c1a5 427 Gene3D G3DSA:1.20.140.10 215 380 1.2E-37 T 06-07-2017 BWK49_RS26085 38958c1c33b8d51bbc7a8dbab289c1a5 427 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 133 202 1.6E-16 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 BWK49_RS26085 38958c1c33b8d51bbc7a8dbab289c1a5 427 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 229 375 7.2E-28 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS26085 38958c1c33b8d51bbc7a8dbab289c1a5 427 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 12 127 3.1E-17 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS26085 38958c1c33b8d51bbc7a8dbab289c1a5 427 Gene3D G3DSA:2.40.110.10 133 214 1.9E-26 T 06-07-2017 BWK49_RS26085 38958c1c33b8d51bbc7a8dbab289c1a5 427 SUPERFAMILY SSF56645 3 237 5.5E-59 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS26085 38958c1c33b8d51bbc7a8dbab289c1a5 427 Gene3D G3DSA:1.10.540.10 4 128 1.6E-25 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS07450 f48f09e65e03f8cfacbff24fec2b0f5f 413 PRINTS PR00359 B-class P450 signature 142 158 9.1E-46 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS07450 f48f09e65e03f8cfacbff24fec2b0f5f 413 PRINTS PR00359 B-class P450 signature 327 342 9.1E-46 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS07450 f48f09e65e03f8cfacbff24fec2b0f5f 413 PRINTS PR00359 B-class P450 signature 358 369 9.1E-46 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS07450 f48f09e65e03f8cfacbff24fec2b0f5f 413 PRINTS PR00359 B-class P450 signature 299 326 9.1E-46 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS07450 f48f09e65e03f8cfacbff24fec2b0f5f 413 PRINTS PR00359 B-class P450 signature 349 358 9.1E-46 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS07450 f48f09e65e03f8cfacbff24fec2b0f5f 413 PRINTS PR00359 B-class P450 signature 282 293 9.1E-46 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS07450 f48f09e65e03f8cfacbff24fec2b0f5f 413 PRINTS PR00359 B-class P450 signature 96 107 9.1E-46 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS07450 f48f09e65e03f8cfacbff24fec2b0f5f 413 PRINTS PR00359 B-class P450 signature 201 223 9.1E-46 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS07450 f48f09e65e03f8cfacbff24fec2b0f5f 413 PRINTS PR00359 B-class P450 signature 159 174 9.1E-46 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS07450 f48f09e65e03f8cfacbff24fec2b0f5f 413 PRINTS PR00385 P450 superfamily signature 349 358 1.5E-8 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS07450 f48f09e65e03f8cfacbff24fec2b0f5f 413 PRINTS PR00385 P450 superfamily signature 282 293 1.5E-8 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS07450 f48f09e65e03f8cfacbff24fec2b0f5f 413 PRINTS PR00385 P450 superfamily signature 358 369 1.5E-8 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS07450 f48f09e65e03f8cfacbff24fec2b0f5f 413 PRINTS PR00385 P450 superfamily signature 247 264 1.5E-8 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS07450 f48f09e65e03f8cfacbff24fec2b0f5f 413 SUPERFAMILY SSF48264 30 406 2.23E-87 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS07450 f48f09e65e03f8cfacbff24fec2b0f5f 413 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 351 360 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 BWK49_RS07450 f48f09e65e03f8cfacbff24fec2b0f5f 413 Pfam PF00067 Cytochrome P450 174 268 1.5E-9 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS07450 f48f09e65e03f8cfacbff24fec2b0f5f 413 Pfam PF00067 Cytochrome P450 279 372 1.2E-18 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS07450 f48f09e65e03f8cfacbff24fec2b0f5f 413 Gene3D G3DSA:1.10.630.10 21 407 2.9E-105 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS00480 af26a411523d53a40ad05d395c744a36 77 SUPERFAMILY SSF54862 3 62 1.02E-10 T 06-07-2017 BWK49_RS00480 af26a411523d53a40ad05d395c744a36 77 Pfam PF13459 4Fe-4S single cluster domain 3 61 2.9E-15 T 06-07-2017 BWK49_RS00480 af26a411523d53a40ad05d395c744a36 77 Gene3D G3DSA:3.30.70.20 2 65 5.1E-17 T 06-07-2017 BWK49_RS10135 80f01c4951266cdd6130e8578ec8d881 140 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 12 90 9.8E-13 T 06-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 BWK49_RS10135 80f01c4951266cdd6130e8578ec8d881 140 Gene3D G3DSA:2.30.110.10 6 134 2.4E-32 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 BWK49_RS10135 80f01c4951266cdd6130e8578ec8d881 140 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 10 133 3.0E-37 T 06-07-2017 IPR019920 F420-binding domain, putative BWK49_RS10135 80f01c4951266cdd6130e8578ec8d881 140 SUPERFAMILY SSF50475 2 132 3.37E-29 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 BWK49_RS12345 190d2277ea663c5b83936b91f5251b79 495 SUPERFAMILY SSF51905 4 229 1.1E-55 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS12345 190d2277ea663c5b83936b91f5251b79 495 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 173 191 2.8E-5 T 06-07-2017 BWK49_RS12345 190d2277ea663c5b83936b91f5251b79 495 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 2.8E-5 T 06-07-2017 BWK49_RS12345 190d2277ea663c5b83936b91f5251b79 495 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 132 141 2.1E-9 T 06-07-2017 BWK49_RS12345 190d2277ea663c5b83936b91f5251b79 495 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 173 198 2.1E-9 T 06-07-2017 BWK49_RS12345 190d2277ea663c5b83936b91f5251b79 495 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 2.1E-9 T 06-07-2017 BWK49_RS12345 190d2277ea663c5b83936b91f5251b79 495 Gene3D G3DSA:3.50.50.60 4 208 1.8E-63 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS12345 190d2277ea663c5b83936b91f5251b79 495 Gene3D G3DSA:3.50.50.60 301 344 1.5E-8 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS12345 190d2277ea663c5b83936b91f5251b79 495 Gene3D G3DSA:3.50.50.60 379 468 1.5E-8 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS12345 190d2277ea663c5b83936b91f5251b79 495 SUPERFAMILY SSF51905 272 453 2.1E-14 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS12345 190d2277ea663c5b83936b91f5251b79 495 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 9 205 2.0E-18 T 06-07-2017 BWK49_RS14890 88284bbebce288364246fa3a63596ae9 719 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 69 8.5E-5 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 BWK49_RS14890 88284bbebce288364246fa3a63596ae9 719 SUPERFAMILY SSF51735 2 192 4.57E-20 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS14890 88284bbebce288364246fa3a63596ae9 719 Gene3D G3DSA:3.40.50.720 3 192 6.0E-17 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS09170 1ff3aebda9c7b1e8caa6ea7cc6be320b 871 SMART SM00382 647 832 5.1E-18 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS09170 1ff3aebda9c7b1e8caa6ea7cc6be320b 871 Pfam PF00005 ABC transporter 639 786 1.1E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 BWK49_RS09170 1ff3aebda9c7b1e8caa6ea7cc6be320b 871 ProSitePatterns PS00211 ABC transporters family signature. 758 772 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 BWK49_RS09170 1ff3aebda9c7b1e8caa6ea7cc6be320b 871 Gene3D G3DSA:1.20.1560.10 297 603 1.1E-36 T 06-07-2017 BWK49_RS09170 1ff3aebda9c7b1e8caa6ea7cc6be320b 871 Gene3D G3DSA:2.40.30.10 15 113 1.1E-23 T 06-07-2017 BWK49_RS09170 1ff3aebda9c7b1e8caa6ea7cc6be320b 871 SUPERFAMILY SSF90123 297 603 4.45E-41 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 BWK49_RS09170 1ff3aebda9c7b1e8caa6ea7cc6be320b 871 Gene3D G3DSA:3.40.50.300 621 850 3.7E-75 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS09170 1ff3aebda9c7b1e8caa6ea7cc6be320b 871 Pfam PF00664 ABC transporter transmembrane region 307 465 2.9E-13 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 BWK49_RS09170 1ff3aebda9c7b1e8caa6ea7cc6be320b 871 SUPERFAMILY SSF63380 14 115 7.17E-10 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 BWK49_RS09170 1ff3aebda9c7b1e8caa6ea7cc6be320b 871 Pfam PF08021 Siderophore-interacting FAD-binding domain 62 114 6.2E-11 T 06-07-2017 IPR013113 FAD-binding 9, siderophore-interacting BWK49_RS09170 1ff3aebda9c7b1e8caa6ea7cc6be320b 871 SUPERFAMILY SSF52540 618 854 2.98E-82 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS09170 1ff3aebda9c7b1e8caa6ea7cc6be320b 871 Gene3D G3DSA:3.40.50.80 124 251 2.1E-28 T 06-07-2017 BWK49_RS09170 1ff3aebda9c7b1e8caa6ea7cc6be320b 871 Pfam PF04954 Siderophore-interacting protein 131 241 5.9E-23 T 06-07-2017 IPR007037 Siderophore-interacting protein BWK49_RS16215 28e1146aea618e11c9fb1f1cb7e34aff 377 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 332 348 1.6E-6 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS16215 28e1146aea618e11c9fb1f1cb7e34aff 377 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 318 332 1.6E-6 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS16215 28e1146aea618e11c9fb1f1cb7e34aff 377 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 348 360 1.6E-6 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS16215 28e1146aea618e11c9fb1f1cb7e34aff 377 Pfam PF00196 Bacterial regulatory proteins, luxR family 318 369 5.2E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS16215 28e1146aea618e11c9fb1f1cb7e34aff 377 SUPERFAMILY SSF46894 305 373 6.8E-15 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 BWK49_RS16215 28e1146aea618e11c9fb1f1cb7e34aff 377 Gene3D G3DSA:3.30.450.20 177 282 2.8E-6 T 06-07-2017 BWK49_RS16215 28e1146aea618e11c9fb1f1cb7e34aff 377 Gene3D G3DSA:1.10.10.10 314 373 1.2E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS16215 28e1146aea618e11c9fb1f1cb7e34aff 377 SMART SM00421 315 372 4.5E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS23075 46ffc9cf8ef752ee038083c34dbc4c9e 402 Gene3D G3DSA:3.30.1540.10 238 318 2.5E-24 T 06-07-2017 BWK49_RS23075 46ffc9cf8ef752ee038083c34dbc4c9e 402 Pfam PF02515 CoA-transferase family III 10 391 5.7E-111 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 BWK49_RS23075 46ffc9cf8ef752ee038083c34dbc4c9e 402 SUPERFAMILY SSF89796 8 396 4.32E-107 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS23075 46ffc9cf8ef752ee038083c34dbc4c9e 402 Gene3D G3DSA:3.40.50.10540 5 222 4.1E-89 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS23075 46ffc9cf8ef752ee038083c34dbc4c9e 402 Gene3D G3DSA:3.40.50.10540 319 396 4.1E-89 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS25010 33533522a8be696dc115a185769e9640 534 Pfam PF07969 Amidohydrolase family 50 532 4.3E-76 T 06-07-2017 IPR013108 Amidohydrolase 3 BWK49_RS25010 33533522a8be696dc115a185769e9640 534 SUPERFAMILY SSF51338 7 62 3.6E-22 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 BWK49_RS25010 33533522a8be696dc115a185769e9640 534 SUPERFAMILY SSF51338 491 533 3.6E-22 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 BWK49_RS25010 33533522a8be696dc115a185769e9640 534 Gene3D G3DSA:2.30.40.10 419 533 1.1E-22 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 BWK49_RS25010 33533522a8be696dc115a185769e9640 534 Gene3D G3DSA:2.30.40.10 7 83 6.8E-14 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 BWK49_RS25010 33533522a8be696dc115a185769e9640 534 SUPERFAMILY SSF51556 127 133 2.45E-23 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS25010 33533522a8be696dc115a185769e9640 534 SUPERFAMILY SSF51556 316 492 2.45E-23 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS25010 33533522a8be696dc115a185769e9640 534 SUPERFAMILY SSF51556 61 87 2.45E-23 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS25010 33533522a8be696dc115a185769e9640 534 SUPERFAMILY SSF51556 200 269 2.45E-23 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS03440 9e85170c6322afe7a8b3d5a4b1fa7405 286 SUPERFAMILY SSF54637 163 281 4.82E-27 T 06-07-2017 IPR029069 HotDog domain BWK49_RS03440 9e85170c6322afe7a8b3d5a4b1fa7405 286 Gene3D G3DSA:3.10.129.10 146 281 7.9E-39 T 06-07-2017 IPR029069 HotDog domain BWK49_RS03440 9e85170c6322afe7a8b3d5a4b1fa7405 286 Gene3D G3DSA:3.10.129.10 1 145 3.7E-48 T 06-07-2017 IPR029069 HotDog domain BWK49_RS03440 9e85170c6322afe7a8b3d5a4b1fa7405 286 Pfam PF01575 MaoC like domain 163 262 1.0E-26 T 06-07-2017 IPR002539 MaoC-like domain BWK49_RS03440 9e85170c6322afe7a8b3d5a4b1fa7405 286 SUPERFAMILY SSF54637 9 158 1.55E-38 T 06-07-2017 IPR029069 HotDog domain BWK49_RS03440 9e85170c6322afe7a8b3d5a4b1fa7405 286 Pfam PF13452 N-terminal half of MaoC dehydratase 12 139 5.2E-12 T 06-07-2017 BWK49_RS06080 fdf2a83727b9ae3773424b034119fc52 425 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 190 416 6.3E-39 T 06-07-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 BWK49_RS06080 fdf2a83727b9ae3773424b034119fc52 425 Gene3D G3DSA:2.102.10.10 46 160 4.7E-24 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS06080 fdf2a83727b9ae3773424b034119fc52 425 SUPERFAMILY SSF55961 171 418 3.69E-38 T 06-07-2017 BWK49_RS06080 fdf2a83727b9ae3773424b034119fc52 425 Gene3D G3DSA:3.90.380.10 161 399 1.9E-25 T 06-07-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 BWK49_RS06080 fdf2a83727b9ae3773424b034119fc52 425 Pfam PF00355 Rieske [2Fe-2S] domain 47 139 8.5E-13 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS06080 fdf2a83727b9ae3773424b034119fc52 425 SUPERFAMILY SSF50022 13 169 1.83E-41 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS06080 fdf2a83727b9ae3773424b034119fc52 425 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 154 180 2.4E-9 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS06080 fdf2a83727b9ae3773424b034119fc52 425 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 31 56 2.4E-9 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS23755 120fc8f126a1c53268ab5f0665a6bdda 582 Pfam PF00890 FAD binding domain 6 38 1.5E-4 T 06-07-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 BWK49_RS23755 120fc8f126a1c53268ab5f0665a6bdda 582 Pfam PF05199 GMC oxidoreductase 472 529 2.0E-11 T 06-07-2017 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 BWK49_RS23755 120fc8f126a1c53268ab5f0665a6bdda 582 SUPERFAMILY SSF51905 474 535 6.48E-47 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS23755 120fc8f126a1c53268ab5f0665a6bdda 582 SUPERFAMILY SSF51905 1 300 6.48E-47 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS23755 120fc8f126a1c53268ab5f0665a6bdda 582 Pfam PF00732 GMC oxidoreductase 189 277 5.7E-6 T 06-07-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 BWK49_RS23755 120fc8f126a1c53268ab5f0665a6bdda 582 Gene3D G3DSA:3.50.50.60 468 535 2.7E-84 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS23755 120fc8f126a1c53268ab5f0665a6bdda 582 Gene3D G3DSA:3.50.50.60 2 125 2.7E-84 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS23755 120fc8f126a1c53268ab5f0665a6bdda 582 Gene3D G3DSA:3.50.50.60 406 419 2.7E-84 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS23755 120fc8f126a1c53268ab5f0665a6bdda 582 Gene3D G3DSA:3.50.50.60 197 302 2.7E-84 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS14110 60dea5ed710a53a28911e9501346a6dc 247 Gene3D G3DSA:3.30.450.40 21 173 2.7E-10 T 06-07-2017 IPR029016 GAF domain-like BWK49_RS14110 60dea5ed710a53a28911e9501346a6dc 247 Pfam PF03861 ANTAR domain 184 236 6.2E-16 T 06-07-2017 IPR005561 ANTAR domain GO:0003723 BWK49_RS14110 60dea5ed710a53a28911e9501346a6dc 247 Pfam PF13185 GAF domain 35 172 1.4E-8 T 06-07-2017 IPR003018 GAF domain GO:0005515 BWK49_RS14110 60dea5ed710a53a28911e9501346a6dc 247 PIRSF PIRSF036625 4 246 8.1E-69 T 06-07-2017 IPR012074 GAF-ANTAR transcription anti-termination regulator, putative BWK49_RS14110 60dea5ed710a53a28911e9501346a6dc 247 SUPERFAMILY SSF52172 178 235 6.46E-8 T 06-07-2017 IPR011006 CheY-like superfamily BWK49_RS14110 60dea5ed710a53a28911e9501346a6dc 247 SMART SM01012 181 236 1.9E-18 T 06-07-2017 IPR005561 ANTAR domain GO:0003723 BWK49_RS14110 60dea5ed710a53a28911e9501346a6dc 247 Gene3D G3DSA:1.10.10.10 184 239 7.4E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS14110 60dea5ed710a53a28911e9501346a6dc 247 SUPERFAMILY SSF55781 13 172 1.34E-13 T 06-07-2017 IPR029016 GAF domain-like BWK49_RS17030 f70f702d3672b4cb00ffef66ef8c2a5a 471 Pfam PF00756 Putative esterase 173 322 1.7E-11 T 06-07-2017 IPR000801 Putative esterase Reactome: R-HSA-156590 BWK49_RS17030 f70f702d3672b4cb00ffef66ef8c2a5a 471 SUPERFAMILY SSF53474 158 438 1.31E-28 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS17030 f70f702d3672b4cb00ffef66ef8c2a5a 471 Gene3D G3DSA:3.40.50.1820 142 439 8.0E-45 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS14915 3f53ef2b874ffb15ae013040fee39365 790 ProSitePatterns PS60002 Phosphoketolase signature 1. 143 149 - T 06-07-2017 IPR019790 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, conserved site GO:0005975|GO:0016832 BWK49_RS14915 3f53ef2b874ffb15ae013040fee39365 790 SUPERFAMILY SSF52518 6 368 9.75E-75 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS14915 3f53ef2b874ffb15ae013040fee39365 790 Pfam PF09363 XFP C-terminal domain 583 786 1.4E-87 T 06-07-2017 IPR018969 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, C-terminal GO:0005975|GO:0016832 BWK49_RS14915 3f53ef2b874ffb15ae013040fee39365 790 Pfam PF09364 XFP N-terminal domain 7 383 2.5E-188 T 06-07-2017 IPR018970 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, N-terminal BWK49_RS14915 3f53ef2b874ffb15ae013040fee39365 790 Pfam PF03894 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase 398 572 5.9E-87 T 06-07-2017 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 BWK49_RS14915 3f53ef2b874ffb15ae013040fee39365 790 SUPERFAMILY SSF52518 375 585 1.18E-23 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS14915 3f53ef2b874ffb15ae013040fee39365 790 ProSitePatterns PS60003 Phosphoketolase signature 2. 156 174 - T 06-07-2017 IPR019789 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, thiamine diphosphate binding site GO:0005975|GO:0016832 BWK49_RS14915 3f53ef2b874ffb15ae013040fee39365 790 PIRSF PIRSF017245 1 788 0.0 T 06-07-2017 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 BWK49_RS14915 3f53ef2b874ffb15ae013040fee39365 790 Gene3D G3DSA:3.40.50.970 6 365 2.1E-22 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS14915 3f53ef2b874ffb15ae013040fee39365 790 Hamap MF_01403 Probable phosphoketolase. 4 788 40.694 T 06-07-2017 IPR023962 Probable phosphoketolase BWK49_RS24815 58391e285506e9538acacea7879b4a1d 503 Gene3D G3DSA:3.50.50.60 17 228 3.9E-55 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS24815 58391e285506e9538acacea7879b4a1d 503 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 191 216 6.0E-7 T 06-07-2017 BWK49_RS24815 58391e285506e9538acacea7879b4a1d 503 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 20 42 6.0E-7 T 06-07-2017 BWK49_RS24815 58391e285506e9538acacea7879b4a1d 503 Pfam PF00743 Flavin-binding monooxygenase-like 21 229 4.8E-16 T 06-07-2017 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 BWK49_RS24815 58391e285506e9538acacea7879b4a1d 503 SUPERFAMILY SSF51905 161 356 1.68E-24 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS24815 58391e285506e9538acacea7879b4a1d 503 SUPERFAMILY SSF51905 18 227 3.89E-50 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS24815 58391e285506e9538acacea7879b4a1d 503 Gene3D G3DSA:3.50.50.60 337 424 9.8E-4 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS22010 a55ae582cc7f3d14317edb1a0ac5a0f5 252 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 45 187 9.1E-48 T 06-07-2017 BWK49_RS22010 a55ae582cc7f3d14317edb1a0ac5a0f5 252 ProSitePatterns PS01099 Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. 145 163 - T 06-07-2017 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS22010 a55ae582cc7f3d14317edb1a0ac5a0f5 252 Gene3D G3DSA:3.40.30.10 109 192 2.4E-9 T 06-07-2017 IPR012336 Thioredoxin-like fold BWK49_RS22010 a55ae582cc7f3d14317edb1a0ac5a0f5 252 PIRSF PIRSF000216 19 245 1.1E-74 T 06-07-2017 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS22010 a55ae582cc7f3d14317edb1a0ac5a0f5 252 SUPERFAMILY SSF52833 43 195 1.23E-46 T 06-07-2017 IPR012336 Thioredoxin-like fold BWK49_RS09165 7ee7d47435e6363d70bb7b8901db8de4 141 Pfam PF04134 Protein of unknown function, DUF393 10 123 2.6E-26 T 06-07-2017 IPR007263 Protein of unknown function DUF393 BWK49_RS01980 dcc76232e755fe93edad277b36bd3380 480 SUPERFAMILY SSF50022 10 157 9.17E-46 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS01980 dcc76232e755fe93edad277b36bd3380 480 Pfam PF00355 Rieske [2Fe-2S] domain 39 122 4.3E-19 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS01980 dcc76232e755fe93edad277b36bd3380 480 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 162 440 6.1E-19 T 06-07-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 BWK49_RS01980 dcc76232e755fe93edad277b36bd3380 480 Gene3D G3DSA:2.102.10.10 27 118 6.1E-17 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS01980 dcc76232e755fe93edad277b36bd3380 480 Gene3D G3DSA:3.90.380.10 129 444 1.2E-97 T 06-07-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 BWK49_RS01980 dcc76232e755fe93edad277b36bd3380 480 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 74 94 1.8E-40 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS01980 dcc76232e755fe93edad277b36bd3380 480 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 141 167 1.8E-40 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS01980 dcc76232e755fe93edad277b36bd3380 480 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 53 68 1.8E-40 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS01980 dcc76232e755fe93edad277b36bd3380 480 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 95 115 1.8E-40 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS01980 dcc76232e755fe93edad277b36bd3380 480 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 23 48 1.8E-40 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS01980 dcc76232e755fe93edad277b36bd3380 480 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 181 203 1.8E-40 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS01980 dcc76232e755fe93edad277b36bd3380 480 SUPERFAMILY SSF55961 157 444 8.63E-52 T 06-07-2017 BWK49_RS01980 dcc76232e755fe93edad277b36bd3380 480 ProSitePatterns PS00570 Bacterial ring hydroxylating dioxygenases alpha-subunit signature. 81 104 - T 06-07-2017 IPR015881 Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site GO:0005506|GO:0016705|GO:0051537|GO:0055114 BWK49_RS01710 dcc76232e755fe93edad277b36bd3380 480 SUPERFAMILY SSF50022 10 157 9.17E-46 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS01710 dcc76232e755fe93edad277b36bd3380 480 Pfam PF00355 Rieske [2Fe-2S] domain 39 122 4.3E-19 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS01710 dcc76232e755fe93edad277b36bd3380 480 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 162 440 6.1E-19 T 06-07-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 BWK49_RS01710 dcc76232e755fe93edad277b36bd3380 480 Gene3D G3DSA:2.102.10.10 27 118 6.1E-17 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS01710 dcc76232e755fe93edad277b36bd3380 480 Gene3D G3DSA:3.90.380.10 129 444 1.2E-97 T 06-07-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 BWK49_RS01710 dcc76232e755fe93edad277b36bd3380 480 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 74 94 1.8E-40 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS01710 dcc76232e755fe93edad277b36bd3380 480 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 141 167 1.8E-40 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS01710 dcc76232e755fe93edad277b36bd3380 480 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 53 68 1.8E-40 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS01710 dcc76232e755fe93edad277b36bd3380 480 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 95 115 1.8E-40 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS01710 dcc76232e755fe93edad277b36bd3380 480 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 23 48 1.8E-40 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS01710 dcc76232e755fe93edad277b36bd3380 480 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 181 203 1.8E-40 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS01710 dcc76232e755fe93edad277b36bd3380 480 SUPERFAMILY SSF55961 157 444 8.63E-52 T 06-07-2017 BWK49_RS01710 dcc76232e755fe93edad277b36bd3380 480 ProSitePatterns PS00570 Bacterial ring hydroxylating dioxygenases alpha-subunit signature. 81 104 - T 06-07-2017 IPR015881 Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site GO:0005506|GO:0016705|GO:0051537|GO:0055114 BWK49_RS12505 7caa313a1856446c31cbe46ddcef06c4 375 Pfam PF06441 Epoxide hydrolase N terminus 4 109 6.1E-38 T 06-07-2017 IPR010497 Epoxide hydrolase, N-terminal KEGG: 00980+3.3.2.9|Reactome: R-HSA-211945 BWK49_RS12505 7caa313a1856446c31cbe46ddcef06c4 375 PIRSF PIRSF001112 1 375 1.1E-139 T 06-07-2017 IPR016292 Epoxide hydrolase GO:0033961 KEGG: 00980+3.3.2.9|Reactome: R-HSA-211945 BWK49_RS12505 7caa313a1856446c31cbe46ddcef06c4 375 SUPERFAMILY SSF53474 4 373 2.14E-108 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS12505 7caa313a1856446c31cbe46ddcef06c4 375 PRINTS PR00412 Epoxide hydrolase signature 127 142 6.3E-18 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS12505 7caa313a1856446c31cbe46ddcef06c4 375 PRINTS PR00412 Epoxide hydrolase signature 348 370 6.3E-18 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS12505 7caa313a1856446c31cbe46ddcef06c4 375 PRINTS PR00412 Epoxide hydrolase signature 100 118 6.3E-18 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS12505 7caa313a1856446c31cbe46ddcef06c4 375 PRINTS PR00412 Epoxide hydrolase signature 317 333 6.3E-18 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS12505 7caa313a1856446c31cbe46ddcef06c4 375 PRINTS PR00412 Epoxide hydrolase signature 172 185 6.3E-18 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS12505 7caa313a1856446c31cbe46ddcef06c4 375 Gene3D G3DSA:3.40.50.1820 2 374 1.7E-150 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS14790 7f7e6c3c977ba1d744493a81ddc749b8 164 Pfam PF02627 Carboxymuconolactone decarboxylase family 20 102 7.6E-7 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 BWK49_RS14790 7f7e6c3c977ba1d744493a81ddc749b8 164 Gene3D G3DSA:1.20.1290.10 12 153 4.1E-35 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 BWK49_RS14790 7f7e6c3c977ba1d744493a81ddc749b8 164 SUPERFAMILY SSF69118 11 152 1.65E-31 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 BWK49_RS08650 220abed6590b88c21a81081906356804 1143 Pfam PF13482 RNase_H superfamily 312 501 1.8E-16 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS08650 220abed6590b88c21a81081906356804 1143 SUPERFAMILY SSF53098 351 506 6.15E-5 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS08650 220abed6590b88c21a81081906356804 1143 Gene3D G3DSA:3.40.50.300 957 1112 1.3E-6 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS08650 220abed6590b88c21a81081906356804 1143 Pfam PF13087 AAA domain 937 1108 1.1E-23 T 06-07-2017 BWK49_RS08650 220abed6590b88c21a81081906356804 1143 Gene3D G3DSA:3.40.50.300 760 956 1.2E-29 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS08650 220abed6590b88c21a81081906356804 1143 TIGRFAM TIGR03491 TIGR03491: putative RecB family nuclease, TM0106 family 71 501 5.3E-48 T 06-07-2017 IPR019993 RecB family nuclease, TM0106, putative BWK49_RS08650 220abed6590b88c21a81081906356804 1143 Pfam PF13604 AAA domain 761 913 4.4E-13 T 06-07-2017 BWK49_RS08650 220abed6590b88c21a81081906356804 1143 SUPERFAMILY SSF52540 845 1114 7.59E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS08650 220abed6590b88c21a81081906356804 1143 SUPERFAMILY SSF52540 760 815 7.59E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS26705 af836e85d95f166380322c9810779297 448 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 24 447 4.2E-117 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 BWK49_RS26705 af836e85d95f166380322c9810779297 448 ProSitePatterns PS00099 Thiolases active site. 430 443 - T 06-07-2017 IPR020610 Thiolase, active site GO:0008152|GO:0016747 BWK49_RS26705 af836e85d95f166380322c9810779297 448 Gene3D G3DSA:3.40.47.10 304 447 2.0E-39 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS26705 af836e85d95f166380322c9810779297 448 Gene3D G3DSA:3.40.47.10 182 226 2.0E-39 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS26705 af836e85d95f166380322c9810779297 448 Pfam PF02803 Thiolase, C-terminal domain 298 447 1.4E-28 T 06-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 BWK49_RS26705 af836e85d95f166380322c9810779297 448 SUPERFAMILY SSF53901 297 446 3.79E-27 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS26705 af836e85d95f166380322c9810779297 448 SUPERFAMILY SSF53901 22 297 7.27E-52 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS26705 af836e85d95f166380322c9810779297 448 Pfam PF00108 Thiolase, N-terminal domain 22 287 1.4E-41 T 06-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 BWK49_RS26705 af836e85d95f166380322c9810779297 448 Gene3D G3DSA:3.40.47.10 227 302 3.9E-42 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS26705 af836e85d95f166380322c9810779297 448 Gene3D G3DSA:3.40.47.10 22 141 3.9E-42 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS26705 af836e85d95f166380322c9810779297 448 PIRSF PIRSF000429 16 448 6.7E-97 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 BWK49_RS17005 0de5c4b3c89f2f9eee811d8ad7de8331 263 Pfam PF00588 SpoU rRNA Methylase family 109 251 1.8E-34 T 06-07-2017 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 BWK49_RS17005 0de5c4b3c89f2f9eee811d8ad7de8331 263 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 28 95 8.7E-6 T 06-07-2017 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 BWK49_RS17005 0de5c4b3c89f2f9eee811d8ad7de8331 263 SUPERFAMILY SSF75217 104 257 2.62E-39 T 06-07-2017 IPR029028 Alpha/beta knot methyltransferases BWK49_RS17005 0de5c4b3c89f2f9eee811d8ad7de8331 263 SMART SM00967 28 98 1.2E-11 T 06-07-2017 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 BWK49_RS17005 0de5c4b3c89f2f9eee811d8ad7de8331 263 Gene3D G3DSA:3.30.1330.30 5 95 2.5E-23 T 06-07-2017 IPR029064 50S ribosomal protein L30e-like BWK49_RS17005 0de5c4b3c89f2f9eee811d8ad7de8331 263 SUPERFAMILY SSF55315 5 95 1.29E-18 T 06-07-2017 IPR029064 50S ribosomal protein L30e-like BWK49_RS17005 0de5c4b3c89f2f9eee811d8ad7de8331 263 Gene3D G3DSA:3.40.1280.10 106 257 3.2E-45 T 06-07-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal BWK49_RS19580 a2123de90581494f7fd930c11061ef6e 219 Pfam PF11575 FhuF 2Fe-2S C-terminal domain 194 214 2.5E-9 T 06-07-2017 IPR024726 Ferric iron reductase, C-terminal GO:0051537 BWK49_RS00505 28c6cf98ec7a3682d5f25c6142f1c308 280 SUPERFAMILY SSF51197 1 277 2.47E-70 T 06-07-2017 BWK49_RS00505 28c6cf98ec7a3682d5f25c6142f1c308 280 Gene3D G3DSA:3.60.130.10 3 278 1.1E-68 T 06-07-2017 BWK49_RS00505 28c6cf98ec7a3682d5f25c6142f1c308 280 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 12 270 2.7E-57 T 06-07-2017 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 BWK49_RS14405 2cd6199aae5e72c2246db36ac34fdbbb 256 SUPERFAMILY SSF51735 12 255 5.34E-75 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS14405 2cd6199aae5e72c2246db36ac34fdbbb 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 89 100 3.3E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS14405 2cd6199aae5e72c2246db36ac34fdbbb 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 161 180 3.3E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS14405 2cd6199aae5e72c2246db36ac34fdbbb 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 148 3.3E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS14405 2cd6199aae5e72c2246db36ac34fdbbb 256 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 14 193 1.7E-4 T 06-07-2017 BWK49_RS14405 2cd6199aae5e72c2246db36ac34fdbbb 256 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 148 176 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS14405 2cd6199aae5e72c2246db36ac34fdbbb 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 20 252 1.4E-56 T 06-07-2017 BWK49_RS14405 2cd6199aae5e72c2246db36ac34fdbbb 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 89 100 1.3E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS14405 2cd6199aae5e72c2246db36ac34fdbbb 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 1.3E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS14405 2cd6199aae5e72c2246db36ac34fdbbb 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 15 32 1.3E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS14405 2cd6199aae5e72c2246db36ac34fdbbb 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 1.3E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS14405 2cd6199aae5e72c2246db36ac34fdbbb 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 1.3E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS14405 2cd6199aae5e72c2246db36ac34fdbbb 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 183 200 1.3E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS14405 2cd6199aae5e72c2246db36ac34fdbbb 256 Gene3D G3DSA:3.40.50.720 9 255 3.2E-78 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS25280 289d2b852fb8a62f9b1da86ace89f690 96 Gene3D G3DSA:1.10.287.1060 5 95 1.8E-17 T 06-07-2017 BWK49_RS25280 289d2b852fb8a62f9b1da86ace89f690 96 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 5 86 7.7E-13 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like BWK49_RS25280 289d2b852fb8a62f9b1da86ace89f690 96 SUPERFAMILY SSF140453 5 96 8.11E-21 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like BWK49_RS25280 289d2b852fb8a62f9b1da86ace89f690 96 Pfam PF06013 Proteins of 100 residues with WXG 5 86 4.5E-12 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like BWK49_RS00340 0ae70312210eee2414130c73e78da605 364 SUPERFAMILY SSF51735 305 364 1.1E-95 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS00340 0ae70312210eee2414130c73e78da605 364 SUPERFAMILY SSF51735 12 194 1.1E-95 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS00340 0ae70312210eee2414130c73e78da605 364 TIGRFAM TIGR03450 mycothiol_INO1: inositol 1-phosphate synthase 13 362 6.2E-220 T 06-07-2017 IPR017815 Myo-inositol 1-phosphate synthase, actinobacteria BWK49_RS00340 0ae70312210eee2414130c73e78da605 364 Gene3D G3DSA:3.30.360.10 199 308 2.1E-48 T 06-07-2017 BWK49_RS00340 0ae70312210eee2414130c73e78da605 364 Pfam PF01658 Myo-inositol-1-phosphate synthase 200 308 3.7E-31 T 06-07-2017 IPR013021 Myo-inositol-1-phosphate synthase, GAPDH-like KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 BWK49_RS00340 0ae70312210eee2414130c73e78da605 364 Gene3D G3DSA:3.40.50.720 9 198 4.2E-116 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS00340 0ae70312210eee2414130c73e78da605 364 Gene3D G3DSA:3.40.50.720 309 362 4.2E-116 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS00340 0ae70312210eee2414130c73e78da605 364 SUPERFAMILY SSF55347 198 308 2.22E-34 T 06-07-2017 BWK49_RS00340 0ae70312210eee2414130c73e78da605 364 PIRSF PIRSF015578 2 363 2.6E-95 T 06-07-2017 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 BWK49_RS24140 f63d5bcc3422f4707ea879f62708b18a 181 SUPERFAMILY SSF52540 2 180 9.18E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS24140 f63d5bcc3422f4707ea879f62708b18a 181 PRINTS PR00094 Adenylate kinase signature 129 144 1.1E-30 T 06-07-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 BWK49_RS24140 f63d5bcc3422f4707ea879f62708b18a 181 PRINTS PR00094 Adenylate kinase signature 81 97 1.1E-30 T 06-07-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 BWK49_RS24140 f63d5bcc3422f4707ea879f62708b18a 181 PRINTS PR00094 Adenylate kinase signature 146 160 1.1E-30 T 06-07-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 BWK49_RS24140 f63d5bcc3422f4707ea879f62708b18a 181 PRINTS PR00094 Adenylate kinase signature 4 17 1.1E-30 T 06-07-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 BWK49_RS24140 f63d5bcc3422f4707ea879f62708b18a 181 PRINTS PR00094 Adenylate kinase signature 32 46 1.1E-30 T 06-07-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 BWK49_RS24140 f63d5bcc3422f4707ea879f62708b18a 181 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 06-07-2017 BWK49_RS24140 f63d5bcc3422f4707ea879f62708b18a 181 Pfam PF00406 Adenylate kinase 5 158 8.3E-53 T 06-07-2017 BWK49_RS24140 f63d5bcc3422f4707ea879f62708b18a 181 Hamap MF_00235 Adenylate kinase [adk]. 1 180 44.705 T 06-07-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 BWK49_RS24140 f63d5bcc3422f4707ea879f62708b18a 181 Gene3D G3DSA:3.40.50.300 2 180 6.1E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS06100 06ba769374c01e26f17a3703d554674d 277 Gene3D G3DSA:3.90.226.10 11 199 2.9E-57 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS06100 06ba769374c01e26f17a3703d554674d 277 Pfam PF00378 Enoyl-CoA hydratase/isomerase 15 258 3.0E-47 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 BWK49_RS06100 06ba769374c01e26f17a3703d554674d 277 Gene3D G3DSA:1.10.12.10 201 259 2.5E-17 T 06-07-2017 IPR014748 Crontonase, C-terminal BWK49_RS06100 06ba769374c01e26f17a3703d554674d 277 SUPERFAMILY SSF52096 4 259 9.21E-79 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS06100 06ba769374c01e26f17a3703d554674d 277 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 100 120 - T 06-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 BWK49_RS15465 8cf3430d1641e39ae6bdc48cd24dee37 269 PRINTS PR00046 Major sigma-70 factor signature 221 233 3.6E-9 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS15465 8cf3430d1641e39ae6bdc48cd24dee37 269 PRINTS PR00046 Major sigma-70 factor signature 73 86 3.6E-9 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS15465 8cf3430d1641e39ae6bdc48cd24dee37 269 PRINTS PR00046 Major sigma-70 factor signature 238 253 3.6E-9 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS15465 8cf3430d1641e39ae6bdc48cd24dee37 269 SUPERFAMILY SSF88659 194 268 2.99E-17 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS15465 8cf3430d1641e39ae6bdc48cd24dee37 269 SUPERFAMILY SSF88659 122 189 1.96E-14 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS15465 8cf3430d1641e39ae6bdc48cd24dee37 269 Gene3D G3DSA:1.10.601.10 33 115 6.0E-15 T 06-07-2017 BWK49_RS15465 8cf3430d1641e39ae6bdc48cd24dee37 269 Pfam PF04542 Sigma-70 region 2 50 118 2.7E-13 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS15465 8cf3430d1641e39ae6bdc48cd24dee37 269 Gene3D G3DSA:1.10.10.10 211 268 2.4E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS15465 8cf3430d1641e39ae6bdc48cd24dee37 269 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 45 268 1.9E-33 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS15465 8cf3430d1641e39ae6bdc48cd24dee37 269 Pfam PF04545 Sigma-70, region 4 219 266 9.2E-18 T 06-07-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS15465 8cf3430d1641e39ae6bdc48cd24dee37 269 Pfam PF04539 Sigma-70 region 3 129 193 3.9E-8 T 06-07-2017 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS15465 8cf3430d1641e39ae6bdc48cd24dee37 269 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 43 268 3.4E-89 T 06-07-2017 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS15465 8cf3430d1641e39ae6bdc48cd24dee37 269 SUPERFAMILY SSF88946 19 118 2.51E-25 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS15465 8cf3430d1641e39ae6bdc48cd24dee37 269 Gene3D G3DSA:1.10.10.10 117 171 3.0E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS09315 512d20c8fb2880b9aaf5b496cc19115c 397 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 257 309 5.1E-5 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS09315 512d20c8fb2880b9aaf5b496cc19115c 397 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 119 1.8E-11 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS09315 512d20c8fb2880b9aaf5b496cc19115c 397 SUPERFAMILY SSF56645 6 240 6.54E-52 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS09315 512d20c8fb2880b9aaf5b496cc19115c 397 Gene3D G3DSA:1.10.540.10 7 120 1.3E-13 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS09315 512d20c8fb2880b9aaf5b496cc19115c 397 Gene3D G3DSA:1.20.140.10 219 308 8.0E-11 T 06-07-2017 BWK49_RS09315 512d20c8fb2880b9aaf5b496cc19115c 397 SUPERFAMILY SSF47203 256 384 1.45E-12 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS09315 512d20c8fb2880b9aaf5b496cc19115c 397 Gene3D G3DSA:2.40.110.10 124 218 2.0E-31 T 06-07-2017 BWK49_RS09315 512d20c8fb2880b9aaf5b496cc19115c 397 Gene3D G3DSA:1.20.140.10 320 384 6.8E-6 T 06-07-2017 BWK49_RS09315 512d20c8fb2880b9aaf5b496cc19115c 397 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 124 216 7.8E-21 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 BWK49_RS18735 7a0cc3196d29651c636756e4cbcc1220 341 Pfam PF04055 Radical SAM superfamily 69 238 2.4E-9 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 BWK49_RS18735 7a0cc3196d29651c636756e4cbcc1220 341 SMART SM00729 62 288 0.0024 T 06-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 BWK49_RS18735 7a0cc3196d29651c636756e4cbcc1220 341 Gene3D G3DSA:3.20.20.70 70 296 2.7E-6 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 BWK49_RS18735 7a0cc3196d29651c636756e4cbcc1220 341 SUPERFAMILY SSF102114 63 276 2.62E-10 T 06-07-2017 BWK49_RS05220 b5702812a579b4a365b62b48db7c0112 548 SUPERFAMILY SSF51905 277 481 3.67E-20 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS05220 b5702812a579b4a365b62b48db7c0112 548 Gene3D G3DSA:3.50.50.60 2 207 7.8E-57 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS05220 b5702812a579b4a365b62b48db7c0112 548 Gene3D G3DSA:3.50.50.60 310 483 2.2E-15 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS05220 b5702812a579b4a365b62b48db7c0112 548 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 8 205 5.0E-21 T 06-07-2017 BWK49_RS05220 b5702812a579b4a365b62b48db7c0112 548 SUPERFAMILY SSF51905 1 251 7.42E-54 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS05220 b5702812a579b4a365b62b48db7c0112 548 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 168 192 1.4E-5 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 BWK49_RS05220 b5702812a579b4a365b62b48db7c0112 548 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 6 28 1.4E-5 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 BWK49_RS25590 5309007de9666d6b419689ba54dc8460 123 Gene3D G3DSA:3.10.180.10 2 119 5.5E-28 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS25590 5309007de9666d6b419689ba54dc8460 123 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 2 115 2.1E-8 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain BWK49_RS25590 5309007de9666d6b419689ba54dc8460 123 SUPERFAMILY SSF54593 2 121 5.1E-24 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS16090 982e2169e29d564d9a825bc73a56df26 320 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 18 291 9.3E-72 T 06-07-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 BWK49_RS16090 982e2169e29d564d9a825bc73a56df26 320 SUPERFAMILY SSF160240 216 289 1.06E-7 T 06-07-2017 BWK49_RS16090 982e2169e29d564d9a825bc73a56df26 320 Gene3D G3DSA:1.20.1510.10 18 210 1.2E-47 T 06-07-2017 IPR027469 Cation efflux protein transmembrane domain BWK49_RS16090 982e2169e29d564d9a825bc73a56df26 320 Pfam PF01545 Cation efflux family 25 210 3.9E-39 T 06-07-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 BWK49_RS16090 982e2169e29d564d9a825bc73a56df26 320 SUPERFAMILY SSF161111 16 213 1.57E-46 T 06-07-2017 BWK49_RS15445 73817bb9c5489bea098668806ac79c4c 200 SUPERFAMILY SSF46689 22 86 4.69E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS15445 73817bb9c5489bea098668806ac79c4c 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 54 77 2.4E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS15445 73817bb9c5489bea098668806ac79c4c 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 46 2.4E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS15445 73817bb9c5489bea098668806ac79c4c 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 34 79 2.2E-13 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS15445 73817bb9c5489bea098668806ac79c4c 200 ProSitePatterns PS01081 TetR-type HTH domain signature. 45 76 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site BWK49_RS15445 73817bb9c5489bea098668806ac79c4c 200 Gene3D G3DSA:1.10.357.10 10 196 6.7E-25 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS28180 377701c893ce51e43c9a4bf6d1d8f20a 125 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 14 116 1.8E-15 T 06-07-2017 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 BWK49_RS28180 377701c893ce51e43c9a4bf6d1d8f20a 125 SUPERFAMILY SSF52091 16 120 5.3E-16 T 06-07-2017 IPR002645 STAS domain BWK49_RS28180 377701c893ce51e43c9a4bf6d1d8f20a 125 Pfam PF13466 STAS domain 27 106 7.1E-10 T 06-07-2017 IPR002645 STAS domain BWK49_RS28180 377701c893ce51e43c9a4bf6d1d8f20a 125 Gene3D G3DSA:3.30.750.24 16 120 2.1E-18 T 06-07-2017 IPR002645 STAS domain BWK49_RS27110 13361112b367aad758708cfc10285fbf 747 SMART SM00926 3 57 1.5E-11 T 06-07-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS27110 13361112b367aad758708cfc10285fbf 747 Gene3D G3DSA:3.40.228.10 151 323 8.0E-41 T 06-07-2017 BWK49_RS27110 13361112b367aad758708cfc10285fbf 747 SUPERFAMILY SSF53706 4 479 7.98E-112 T 06-07-2017 BWK49_RS27110 13361112b367aad758708cfc10285fbf 747 Pfam PF01568 Molydopterin dinucleotide binding domain 633 733 6.7E-14 T 06-07-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 BWK49_RS27110 13361112b367aad758708cfc10285fbf 747 Gene3D G3DSA:2.40.40.20 606 740 3.1E-15 T 06-07-2017 BWK49_RS27110 13361112b367aad758708cfc10285fbf 747 Pfam PF00384 Molybdopterin oxidoreductase 60 438 2.8E-30 T 06-07-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS27110 13361112b367aad758708cfc10285fbf 747 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 5 54 1.9E-10 T 06-07-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS27110 13361112b367aad758708cfc10285fbf 747 Gene3D G3DSA:3.40.50.740 324 488 1.0E-45 T 06-07-2017 BWK49_RS27110 13361112b367aad758708cfc10285fbf 747 Gene3D G3DSA:3.40.50.740 62 136 1.0E-45 T 06-07-2017 BWK49_RS27110 13361112b367aad758708cfc10285fbf 747 Gene3D G3DSA:2.20.25.90 4 61 1.5E-14 T 06-07-2017 BWK49_RS27110 13361112b367aad758708cfc10285fbf 747 SUPERFAMILY SSF50692 606 740 2.94E-23 T 06-07-2017 IPR009010 Aspartate decarboxylase-like domain BWK49_RS04365 f634ba80b5dfbacc7fd3b2180974528a 75 Pfam PF01402 Ribbon-helix-helix protein, copG family 6 41 3.1E-5 T 06-07-2017 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 BWK49_RS17285 bf63702b31371320adb010b8e152c8a5 512 Gene3D G3DSA:3.60.120.10 20 502 2.1E-162 T 06-07-2017 IPR005801 ADC synthase GO:0009058 BWK49_RS17285 bf63702b31371320adb010b8e152c8a5 512 Pfam PF00425 chorismate binding enzyme 231 489 6.8E-92 T 06-07-2017 IPR015890 Chorismate-utilising enzyme, C-terminal BWK49_RS17285 bf63702b31371320adb010b8e152c8a5 512 TIGRFAM TIGR00564 trpE_most: anthranilate synthase component I 32 497 5.6E-161 T 06-07-2017 IPR005256 Anthranilate synthase component I, PabB-like GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 BWK49_RS17285 bf63702b31371320adb010b8e152c8a5 512 Pfam PF04715 Anthranilate synthase component I, N terminal region 33 174 2.5E-31 T 06-07-2017 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058|GO:0016833 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 BWK49_RS17285 bf63702b31371320adb010b8e152c8a5 512 SUPERFAMILY SSF56322 22 498 1.01E-147 T 06-07-2017 IPR005801 ADC synthase GO:0009058 BWK49_RS17285 bf63702b31371320adb010b8e152c8a5 512 PRINTS PR00095 Anthranilate synthase component I signature 337 350 1.9E-24 T 06-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 BWK49_RS17285 bf63702b31371320adb010b8e152c8a5 512 PRINTS PR00095 Anthranilate synthase component I signature 446 460 1.9E-24 T 06-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 BWK49_RS17285 bf63702b31371320adb010b8e152c8a5 512 PRINTS PR00095 Anthranilate synthase component I signature 351 364 1.9E-24 T 06-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 BWK49_RS17285 bf63702b31371320adb010b8e152c8a5 512 PRINTS PR00095 Anthranilate synthase component I signature 431 445 1.9E-24 T 06-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 BWK49_RS20915 a61fbc70961d49521ecf73bde1751377 336 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 2 317 1.9E-86 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 BWK49_RS20915 a61fbc70961d49521ecf73bde1751377 336 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 231 250 - T 06-07-2017 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 BWK49_RS20915 a61fbc70961d49521ecf73bde1751377 336 Gene3D G3DSA:3.40.718.10 2 330 6.5E-114 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 BWK49_RS20915 a61fbc70961d49521ecf73bde1751377 336 SMART SM01329 2 332 2.9E-158 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 BWK49_RS20915 a61fbc70961d49521ecf73bde1751377 336 SUPERFAMILY SSF53659 2 333 5.33E-108 T 06-07-2017 BWK49_RS20915 a61fbc70961d49521ecf73bde1751377 336 Hamap MF_01035 3-isopropylmalate dehydrogenase [leuB]. 1 336 60.585 T 06-07-2017 IPR023698 3-isopropylmalate dehydrogenase GO:0003862|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 BWK49_RS16235 0643f6e7ad72ba1a1de6ad6fb4fe1359 306 TIGRFAM TIGR03619 F420_Rv2161c: probable F420-dependent oxidoreductase, Rv2161c family 32 275 1.1E-55 T 06-07-2017 IPR019921 Luciferase-like, F420-dependent oxidoreductase, Rv2161c, predicted BWK49_RS16235 0643f6e7ad72ba1a1de6ad6fb4fe1359 306 Pfam PF00296 Luciferase-like monooxygenase 1 232 2.2E-48 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS16235 0643f6e7ad72ba1a1de6ad6fb4fe1359 306 SUPERFAMILY SSF51679 1 305 5.77E-62 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS16235 0643f6e7ad72ba1a1de6ad6fb4fe1359 306 Gene3D G3DSA:3.20.20.30 28 305 2.8E-61 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS24995 7d4db64823849d004973991045547f1b 549 Hamap MF_01659 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase [menD]. 1 549 30.276 T 06-07-2017 IPR004433 Menaquinone biosynthesis protein MenD GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 BWK49_RS24995 7d4db64823849d004973991045547f1b 549 SUPERFAMILY SSF52518 5 187 1.23E-30 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS24995 7d4db64823849d004973991045547f1b 549 Gene3D G3DSA:3.40.50.970 326 537 1.6E-19 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS24995 7d4db64823849d004973991045547f1b 549 TIGRFAM TIGR00173 menD: 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase 7 415 5.1E-103 T 06-07-2017 IPR004433 Menaquinone biosynthesis protein MenD GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 BWK49_RS24995 7d4db64823849d004973991045547f1b 549 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 7 184 6.0E-28 T 06-07-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 BWK49_RS24995 7d4db64823849d004973991045547f1b 549 Gene3D G3DSA:3.40.50.970 3 191 5.4E-45 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS24995 7d4db64823849d004973991045547f1b 549 PIRSF PIRSF004983 1 549 1.3E-146 T 06-07-2017 IPR004433 Menaquinone biosynthesis protein MenD GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 BWK49_RS24995 7d4db64823849d004973991045547f1b 549 SUPERFAMILY SSF52518 351 532 9.11E-18 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS16925 5a4171cce8632686e0fd20adcd6e140f 2131 Pfam PF08990 Erythronolide synthase docking 19 40 1.5E-7 T 06-07-2017 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 BWK49_RS16925 5a4171cce8632686e0fd20adcd6e140f 2131 SUPERFAMILY SSF53901 46 417 2.82E-100 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS16925 5a4171cce8632686e0fd20adcd6e140f 2131 SUPERFAMILY SSF47336 1961 2047 7.98E-23 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS16925 5a4171cce8632686e0fd20adcd6e140f 2131 Gene3D G3DSA:3.40.50.720 1458 1648 2.0E-44 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS16925 5a4171cce8632686e0fd20adcd6e140f 2131 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 577 868 4.2E-105 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain BWK49_RS16925 5a4171cce8632686e0fd20adcd6e140f 2131 Gene3D G3DSA:3.90.180.10 1375 1447 4.7E-12 T 06-07-2017 IPR011032 GroES-like BWK49_RS16925 5a4171cce8632686e0fd20adcd6e140f 2131 SUPERFAMILY SSF51735 1466 1604 1.58E-35 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS16925 5a4171cce8632686e0fd20adcd6e140f 2131 SUPERFAMILY SSF52151 574 701 3.66E-72 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 BWK49_RS16925 5a4171cce8632686e0fd20adcd6e140f 2131 SUPERFAMILY SSF52151 762 858 3.66E-72 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 BWK49_RS16925 5a4171cce8632686e0fd20adcd6e140f 2131 SMART SM00826 936 1095 8.9E-80 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS16925 5a4171cce8632686e0fd20adcd6e140f 2131 SUPERFAMILY SSF55048 700 761 7.59E-11 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 BWK49_RS16925 5a4171cce8632686e0fd20adcd6e140f 2131 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1995 2010 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site BWK49_RS16925 5a4171cce8632686e0fd20adcd6e140f 2131 Pfam PF00550 Phosphopantetheine attachment site 1972 2036 1.7E-13 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS16925 5a4171cce8632686e0fd20adcd6e140f 2131 SUPERFAMILY SSF51735 1682 1946 1.93E-46 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS16925 5a4171cce8632686e0fd20adcd6e140f 2131 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 47 294 2.6E-86 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal BWK49_RS16925 5a4171cce8632686e0fd20adcd6e140f 2131 SMART SM00829 1371 1673 3.5E-169 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 BWK49_RS16925 5a4171cce8632686e0fd20adcd6e140f 2131 Gene3D G3DSA:3.40.47.10 307 473 7.2E-67 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS16925 5a4171cce8632686e0fd20adcd6e140f 2131 Gene3D G3DSA:3.30.70.250 701 760 3.5E-7 T 06-07-2017 BWK49_RS16925 5a4171cce8632686e0fd20adcd6e140f 2131 Gene3D G3DSA:3.40.50.720 1682 1867 9.2E-38 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS16925 5a4171cce8632686e0fd20adcd6e140f 2131 SUPERFAMILY SSF50129 1370 1500 2.74E-26 T 06-07-2017 IPR011032 GroES-like BWK49_RS16925 5a4171cce8632686e0fd20adcd6e140f 2131 SMART SM00825 Beta-ketoacyl synthase 49 472 3.5E-214 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain BWK49_RS16925 5a4171cce8632686e0fd20adcd6e140f 2131 Pfam PF08659 KR domain 1685 1864 1.5E-57 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS16925 5a4171cce8632686e0fd20adcd6e140f 2131 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 302 419 9.1E-43 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal BWK49_RS16925 5a4171cce8632686e0fd20adcd6e140f 2131 Gene3D G3DSA:3.40.47.10 49 306 2.8E-86 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS16925 5a4171cce8632686e0fd20adcd6e140f 2131 Gene3D G3DSA:3.40.366.10 761 872 2.3E-76 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 BWK49_RS16925 5a4171cce8632686e0fd20adcd6e140f 2131 Gene3D G3DSA:3.40.366.10 565 695 2.3E-76 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 BWK49_RS16925 5a4171cce8632686e0fd20adcd6e140f 2131 Pfam PF00698 Acyl transferase domain 575 886 1.3E-61 T 06-07-2017 IPR014043 Acyl transferase BWK49_RS16925 5a4171cce8632686e0fd20adcd6e140f 2131 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 207 223 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site BWK49_RS16925 5a4171cce8632686e0fd20adcd6e140f 2131 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 422 539 2.9E-15 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS16925 5a4171cce8632686e0fd20adcd6e140f 2131 SMART SM00823 Phosphopantetheine attachment site 1969 2040 8.4E-31 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS16925 5a4171cce8632686e0fd20adcd6e140f 2131 Gene3D G3DSA:1.10.1200.10 1965 2041 1.4E-23 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS16925 5a4171cce8632686e0fd20adcd6e140f 2131 SMART SM01294 1970 2036 7.2E-6 T 06-07-2017 BWK49_RS16925 5a4171cce8632686e0fd20adcd6e140f 2131 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 1389 1445 3.5E-6 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 BWK49_RS16925 5a4171cce8632686e0fd20adcd6e140f 2131 Pfam PF13602 Zinc-binding dehydrogenase 1543 1673 5.7E-17 T 06-07-2017 BWK49_RS16925 5a4171cce8632686e0fd20adcd6e140f 2131 SUPERFAMILY SSF51735 1149 1348 1.81E-22 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS16925 5a4171cce8632686e0fd20adcd6e140f 2131 Pfam PF14765 Polyketide synthase dehydratase 936 1204 9.4E-57 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS16925 5a4171cce8632686e0fd20adcd6e140f 2131 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1685 1865 2.6E-51 T 06-07-2017 BWK49_RS14445 6227c57e0e3aa03a42fe697f52b10023 484 Gene3D G3DSA:3.40.605.10 11 268 1.7E-87 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 BWK49_RS14445 6227c57e0e3aa03a42fe697f52b10023 484 Pfam PF00171 Aldehyde dehydrogenase family 18 480 1.1E-164 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 BWK49_RS14445 6227c57e0e3aa03a42fe697f52b10023 484 SUPERFAMILY SSF53720 5 483 3.93E-157 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 BWK49_RS14445 6227c57e0e3aa03a42fe697f52b10023 484 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 256 263 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 BWK49_RS14445 6227c57e0e3aa03a42fe697f52b10023 484 Gene3D G3DSA:3.40.309.10 269 455 1.3E-68 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 BWK49_RS05825 9a0b92ad9a006d15226888917e2e528c 468 Pfam PF00501 AMP-binding enzyme 5 371 2.0E-72 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS05825 9a0b92ad9a006d15226888917e2e528c 468 Pfam PF13193 AMP-binding enzyme C-terminal domain 379 452 8.1E-17 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS05825 9a0b92ad9a006d15226888917e2e528c 468 ProSitePatterns PS00455 Putative AMP-binding domain signature. 128 139 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS05825 9a0b92ad9a006d15226888917e2e528c 468 Gene3D G3DSA:3.40.50.980 137 290 1.2E-33 T 06-07-2017 BWK49_RS05825 9a0b92ad9a006d15226888917e2e528c 468 Gene3D G3DSA:2.30.38.10 291 361 2.5E-21 T 06-07-2017 BWK49_RS05825 9a0b92ad9a006d15226888917e2e528c 468 Gene3D G3DSA:3.30.300.30 367 461 1.0E-29 T 06-07-2017 BWK49_RS05825 9a0b92ad9a006d15226888917e2e528c 468 SUPERFAMILY SSF56801 5 461 3.79E-123 T 06-07-2017 BWK49_RS05825 9a0b92ad9a006d15226888917e2e528c 468 Gene3D G3DSA:3.40.50.980 5 136 3.6E-23 T 06-07-2017 BWK49_RS23365 316ea3e70f5b91769dd947f0d2079096 527 SUPERFAMILY SSF53738 281 422 1.06E-25 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 BWK49_RS23365 316ea3e70f5b91769dd947f0d2079096 527 Gene3D G3DSA:3.40.120.10 20 195 1.9E-52 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 BWK49_RS23365 316ea3e70f5b91769dd947f0d2079096 527 Gene3D G3DSA:3.40.120.10 285 424 4.5E-32 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 BWK49_RS23365 316ea3e70f5b91769dd947f0d2079096 527 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 131 140 - T 06-07-2017 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 BWK49_RS23365 316ea3e70f5b91769dd947f0d2079096 527 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 36 170 1.8E-38 T 06-07-2017 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 BWK49_RS23365 316ea3e70f5b91769dd947f0d2079096 527 Gene3D G3DSA:3.40.120.10 208 284 1.2E-18 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 BWK49_RS23365 316ea3e70f5b91769dd947f0d2079096 527 Gene3D G3DSA:3.30.310.50 442 518 1.2E-8 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 BWK49_RS23365 316ea3e70f5b91769dd947f0d2079096 527 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 205 289 1.1E-20 T 06-07-2017 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 BWK49_RS23365 316ea3e70f5b91769dd947f0d2079096 527 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 301 421 2.9E-19 T 06-07-2017 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 BWK49_RS23365 316ea3e70f5b91769dd947f0d2079096 527 SUPERFAMILY SSF53738 26 196 1.81E-43 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 BWK49_RS23365 316ea3e70f5b91769dd947f0d2079096 527 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 206 225 4.9E-9 T 06-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 BWK49_RS23365 316ea3e70f5b91769dd947f0d2079096 527 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 273 288 4.9E-9 T 06-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 BWK49_RS23365 316ea3e70f5b91769dd947f0d2079096 527 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 130 144 4.9E-9 T 06-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 BWK49_RS23365 316ea3e70f5b91769dd947f0d2079096 527 SUPERFAMILY SSF55957 414 523 2.49E-12 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 BWK49_RS23365 316ea3e70f5b91769dd947f0d2079096 527 SUPERFAMILY SSF53738 190 289 3.85E-19 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 BWK49_RS23365 316ea3e70f5b91769dd947f0d2079096 527 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 478 498 3.0E-6 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 BWK49_RS08985 bd6c37d9d49aa60b3c9f02e52cd16442 194 SUPERFAMILY SSF89028 7 184 7.65E-60 T 06-07-2017 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 BWK49_RS08985 bd6c37d9d49aa60b3c9f02e52cd16442 194 Pfam PF01923 Cobalamin adenosyltransferase 8 175 5.1E-59 T 06-07-2017 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 BWK49_RS08985 bd6c37d9d49aa60b3c9f02e52cd16442 194 Gene3D G3DSA:1.20.1200.10 17 187 2.0E-60 T 06-07-2017 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 BWK49_RS08985 bd6c37d9d49aa60b3c9f02e52cd16442 194 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 14 146 4.0E-66 T 06-07-2017 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 BWK49_RS08985 bd6c37d9d49aa60b3c9f02e52cd16442 194 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 9 179 2.1E-51 T 06-07-2017 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 BWK49_RS13720 593da34f891f24fe2675640ff6dec611 667 SUPERFAMILY SSF56112 17 299 4.72E-33 T 06-07-2017 IPR011009 Protein kinase-like domain BWK49_RS13720 593da34f891f24fe2675640ff6dec611 667 SUPERFAMILY SSF159245 362 658 3.14E-22 T 06-07-2017 BWK49_RS13720 593da34f891f24fe2675640ff6dec611 667 Gene3D G3DSA:3.90.1200.10 147 353 1.9E-19 T 06-07-2017 BWK49_RS13720 593da34f891f24fe2675640ff6dec611 667 Pfam PF02958 Ecdysteroid kinase 206 289 9.4E-16 T 06-07-2017 IPR004119 Protein of unknown function DUF227 BWK49_RS13720 593da34f891f24fe2675640ff6dec611 667 SMART SM00587 153 295 1.0E-4 T 06-07-2017 IPR015897 CHK kinase-like BWK49_RS26290 55abab8c7104df55a8e7c63e3ed4b984 502 Gene3D G3DSA:3.40.50.10330 259 328 2.4E-5 T 06-07-2017 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 BWK49_RS26290 55abab8c7104df55a8e7c63e3ed4b984 502 Pfam PF01569 PAP2 superfamily 78 186 4.7E-16 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase BWK49_RS26290 55abab8c7104df55a8e7c63e3ed4b984 502 Pfam PF00781 Diacylglycerol kinase catalytic domain 214 327 5.5E-19 T 06-07-2017 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 BWK49_RS26290 55abab8c7104df55a8e7c63e3ed4b984 502 SUPERFAMILY SSF48317 18 190 1.44E-34 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase BWK49_RS26290 55abab8c7104df55a8e7c63e3ed4b984 502 Gene3D G3DSA:1.20.144.10 19 182 1.7E-29 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase BWK49_RS26290 55abab8c7104df55a8e7c63e3ed4b984 502 SMART SM00014 75 184 3.6E-15 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase BWK49_RS26290 55abab8c7104df55a8e7c63e3ed4b984 502 SMART SM00046 213 327 6.7E-5 T 06-07-2017 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 BWK49_RS26290 55abab8c7104df55a8e7c63e3ed4b984 502 SUPERFAMILY SSF111331 213 494 4.45E-52 T 06-07-2017 IPR016064 NAD kinase/diacylglycerol kinase-like domain BWK49_RS10470 ce769fbefae9efaa662c1e635e448284 1346 SUPERFAMILY SSF56801 60 560 2.75E-112 T 06-07-2017 BWK49_RS10470 ce769fbefae9efaa662c1e635e448284 1346 SMART SM00823 Phosphopantetheine attachment site 548 616 7.5E-4 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS10470 ce769fbefae9efaa662c1e635e448284 1346 SUPERFAMILY SSF51161 1206 1325 4.02E-17 T 06-07-2017 IPR011004 Trimeric LpxA-like BWK49_RS10470 ce769fbefae9efaa662c1e635e448284 1346 Gene3D G3DSA:3.40.50.980 63 218 1.1E-32 T 06-07-2017 BWK49_RS10470 ce769fbefae9efaa662c1e635e448284 1346 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 808 836 - T 06-07-2017 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 BWK49_RS10470 ce769fbefae9efaa662c1e635e448284 1346 ProSitePatterns PS00012 Phosphopantetheine attachment site. 572 587 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site BWK49_RS10470 ce769fbefae9efaa662c1e635e448284 1346 Pfam PF00550 Phosphopantetheine attachment site 550 612 9.1E-14 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS10470 ce769fbefae9efaa662c1e635e448284 1346 ProSitePatterns PS00455 Putative AMP-binding domain signature. 195 206 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS10470 ce769fbefae9efaa662c1e635e448284 1346 Gene3D G3DSA:2.160.10.10 769 849 3.0E-13 T 06-07-2017 BWK49_RS10470 ce769fbefae9efaa662c1e635e448284 1346 Gene3D G3DSA:2.160.10.10 1225 1325 2.4E-19 T 06-07-2017 BWK49_RS10470 ce769fbefae9efaa662c1e635e448284 1346 SUPERFAMILY SSF47336 546 613 1.96E-13 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS10470 ce769fbefae9efaa662c1e635e448284 1346 Gene3D G3DSA:3.30.300.30 437 537 6.0E-22 T 06-07-2017 BWK49_RS10470 ce769fbefae9efaa662c1e635e448284 1346 Pfam PF00501 AMP-binding enzyme 70 168 4.7E-17 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS10470 ce769fbefae9efaa662c1e635e448284 1346 Pfam PF00501 AMP-binding enzyme 192 442 3.2E-52 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS10470 ce769fbefae9efaa662c1e635e448284 1346 SUPERFAMILY SSF51161 758 851 5.96E-16 T 06-07-2017 IPR011004 Trimeric LpxA-like BWK49_RS10470 ce769fbefae9efaa662c1e635e448284 1346 Gene3D G3DSA:1.10.1200.10 542 615 1.8E-17 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS10470 ce769fbefae9efaa662c1e635e448284 1346 Gene3D G3DSA:3.40.50.980 228 359 2.4E-35 T 06-07-2017 BWK49_RS10470 ce769fbefae9efaa662c1e635e448284 1346 SUPERFAMILY SSF51161 928 1089 6.65E-17 T 06-07-2017 IPR011004 Trimeric LpxA-like BWK49_RS10470 ce769fbefae9efaa662c1e635e448284 1346 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 801 834 1.2E-4 T 06-07-2017 IPR001451 Hexapeptide repeat BWK49_RS10470 ce769fbefae9efaa662c1e635e448284 1346 Gene3D G3DSA:2.160.10.10 988 1093 1.3E-10 T 06-07-2017 BWK49_RS10470 ce769fbefae9efaa662c1e635e448284 1346 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 91 466 1.9E-97 T 06-07-2017 IPR010071 Amino acid adenylation domain BWK49_RS10470 ce769fbefae9efaa662c1e635e448284 1346 Gene3D G3DSA:2.30.38.10 360 431 2.0E-14 T 06-07-2017 BWK49_RS10470 ce769fbefae9efaa662c1e635e448284 1346 TIGRFAM TIGR02353 NRPS_term_dom: non-ribosomal peptide synthetase terminal domain of unknown function 636 1323 1.1E-211 T 06-07-2017 IPR012728 Non-ribosomal peptide synthetase, C-terminal BWK49_RS01890 c007e45e5d4c227105f8776172caed85 360 Gene3D G3DSA:2.130.10.10 22 349 2.6E-45 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 BWK49_RS01890 c007e45e5d4c227105f8776172caed85 360 SUPERFAMILY SSF110296 119 348 2.35E-33 T 06-07-2017 BWK49_RS06470 057e79fb3ff5731f81688e34d801ed22 147 SUPERFAMILY SSF55961 1 140 8.71E-30 T 06-07-2017 BWK49_RS06470 057e79fb3ff5731f81688e34d801ed22 147 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 6 140 1.1E-17 T 06-07-2017 IPR019587 Polyketide cyclase/dehydrase BWK49_RS06470 057e79fb3ff5731f81688e34d801ed22 147 Gene3D G3DSA:3.30.530.20 7 142 3.0E-13 T 06-07-2017 IPR023393 START-like domain BWK49_RS24750 f2e042f780352eb6710a61e7a0ea26f9 371 ProSitePatterns PS00117 Galactose-1-phosphate uridyl transferase family 1 active site signature. 184 201 - T 06-07-2017 IPR019779 Galactose-1-phosphate uridyl transferase, class I His-active site GO:0006012|GO:0008108|GO:0008270 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 BWK49_RS24750 f2e042f780352eb6710a61e7a0ea26f9 371 Gene3D G3DSA:3.30.428.10 210 370 1.1E-42 T 06-07-2017 IPR011146 HIT-like domain GO:0003824 BWK49_RS24750 f2e042f780352eb6710a61e7a0ea26f9 371 SUPERFAMILY SSF54197 214 370 7.14E-35 T 06-07-2017 IPR011146 HIT-like domain GO:0003824 BWK49_RS24750 f2e042f780352eb6710a61e7a0ea26f9 371 Pfam PF02744 Galactose-1-phosphate uridyl transferase, C-terminal domain 222 334 3.8E-13 T 06-07-2017 IPR005850 Galactose-1-phosphate uridyl transferase, C-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 BWK49_RS24750 f2e042f780352eb6710a61e7a0ea26f9 371 TIGRFAM TIGR00209 galT_1: galactose-1-phosphate uridylyltransferase 52 370 4.6E-40 T 06-07-2017 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0006012|GO:0008108|GO:0008270 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 BWK49_RS24750 f2e042f780352eb6710a61e7a0ea26f9 371 Gene3D G3DSA:3.30.428.10 76 208 3.7E-40 T 06-07-2017 IPR011146 HIT-like domain GO:0003824 BWK49_RS24750 f2e042f780352eb6710a61e7a0ea26f9 371 PIRSF PIRSF000808 46 371 1.8E-112 T 06-07-2017 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0006012|GO:0008108|GO:0008270 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 BWK49_RS24750 f2e042f780352eb6710a61e7a0ea26f9 371 Pfam PF01087 Galactose-1-phosphate uridyl transferase, N-terminal domain 50 208 5.8E-46 T 06-07-2017 IPR005849 Galactose-1-phosphate uridyl transferase, N-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 BWK49_RS24750 f2e042f780352eb6710a61e7a0ea26f9 371 SUPERFAMILY SSF54197 49 209 8.38E-51 T 06-07-2017 IPR011146 HIT-like domain GO:0003824 BWK49_RS27385 c10bec1086bf2b0da8229135cbcf763d 272 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 12 243 1.2E-47 T 06-07-2017 IPR013658 SMP-30/Gluconolactonase/LRE-like region BWK49_RS27385 c10bec1086bf2b0da8229135cbcf763d 272 Gene3D G3DSA:2.120.10.30 5 249 9.6E-52 T 06-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like BWK49_RS27385 c10bec1086bf2b0da8229135cbcf763d 272 SUPERFAMILY SSF63829 4 246 3.76E-46 T 06-07-2017 BWK49_RS27385 c10bec1086bf2b0da8229135cbcf763d 272 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 183 200 1.3E-6 T 06-07-2017 IPR005511 Senescence marker protein-30 (SMP-30) BWK49_RS27385 c10bec1086bf2b0da8229135cbcf763d 272 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 225 243 1.3E-6 T 06-07-2017 IPR005511 Senescence marker protein-30 (SMP-30) BWK49_RS27385 c10bec1086bf2b0da8229135cbcf763d 272 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 123 145 1.3E-6 T 06-07-2017 IPR005511 Senescence marker protein-30 (SMP-30) BWK49_RS13455 a15f42266c7b087fafec351cb482dc53 253 Pfam PF14230 Domain of unknown function (DUF4333) 163 245 3.7E-26 T 06-07-2017 IPR025637 Domain of unknown function DUF4333 BWK49_RS26460 d944e783591f89adbbcc7c4e4771f6a3 610 SMART SM00382 356 495 2.4E-5 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS26460 d944e783591f89adbbcc7c4e4771f6a3 610 TIGRFAM TIGR03922 T7SS_EccA: type VII secretion AAA-ATPase EccA 50 602 5.7E-268 T 06-07-2017 IPR023835 Type VII secretion system AAA-ATPase, EccA BWK49_RS26460 d944e783591f89adbbcc7c4e4771f6a3 610 Gene3D G3DSA:3.40.50.300 317 508 6.2E-26 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS26460 d944e783591f89adbbcc7c4e4771f6a3 610 SUPERFAMILY SSF52540 315 530 1.77E-33 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS26460 d944e783591f89adbbcc7c4e4771f6a3 610 PRINTS PR00819 CbxX/CfqX superfamily signature 397 411 2.1E-54 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 BWK49_RS26460 d944e783591f89adbbcc7c4e4771f6a3 610 PRINTS PR00819 CbxX/CfqX superfamily signature 442 454 2.1E-54 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 BWK49_RS26460 d944e783591f89adbbcc7c4e4771f6a3 610 PRINTS PR00819 CbxX/CfqX superfamily signature 359 374 2.1E-54 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 BWK49_RS26460 d944e783591f89adbbcc7c4e4771f6a3 610 PRINTS PR00819 CbxX/CfqX superfamily signature 480 499 2.1E-54 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 BWK49_RS26460 d944e783591f89adbbcc7c4e4771f6a3 610 PRINTS PR00819 CbxX/CfqX superfamily signature 463 480 2.1E-54 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 BWK49_RS26460 d944e783591f89adbbcc7c4e4771f6a3 610 PRINTS PR00819 CbxX/CfqX superfamily signature 411 430 2.1E-54 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 BWK49_RS26460 d944e783591f89adbbcc7c4e4771f6a3 610 PRINTS PR00819 CbxX/CfqX superfamily signature 319 333 2.1E-54 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 BWK49_RS26460 d944e783591f89adbbcc7c4e4771f6a3 610 PRINTS PR00819 CbxX/CfqX superfamily signature 550 562 2.1E-54 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 BWK49_RS26460 d944e783591f89adbbcc7c4e4771f6a3 610 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 361 492 6.5E-19 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 BWK49_RS22685 77e43c15565e370db38a88237a9a03a9 228 Pfam PF00440 Bacterial regulatory proteins, tetR family 47 90 1.5E-16 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS22685 77e43c15565e370db38a88237a9a03a9 228 SUPERFAMILY SSF48498 111 222 1.33E-26 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS22685 77e43c15565e370db38a88237a9a03a9 228 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 57 3.3E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS22685 77e43c15565e370db38a88237a9a03a9 228 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 65 88 3.3E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS22685 77e43c15565e370db38a88237a9a03a9 228 Gene3D G3DSA:1.10.10.60 34 90 1.9E-21 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS22685 77e43c15565e370db38a88237a9a03a9 228 Gene3D G3DSA:1.10.357.10 91 221 1.7E-21 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS22685 77e43c15565e370db38a88237a9a03a9 228 SUPERFAMILY SSF46689 31 113 4.17E-19 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS11235 622038ab8d59d1fa91501d2f53107889 155 SUPERFAMILY SSF54534 70 143 2.62E-9 T 06-07-2017 BWK49_RS11235 622038ab8d59d1fa91501d2f53107889 155 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 73 143 1.2E-9 T 06-07-2017 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 BWK49_RS11235 622038ab8d59d1fa91501d2f53107889 155 PIRSF PIRSF006092 1 147 6.3E-11 T 06-07-2017 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 BWK49_RS11235 622038ab8d59d1fa91501d2f53107889 155 Gene3D G3DSA:3.10.50.30 66 146 1.4E-10 T 06-07-2017 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 BWK49_RS04720 4f1433562feb48a0121944da3bff7737 384 SUPERFAMILY SSF47203 228 382 6.12E-38 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS04720 4f1433562feb48a0121944da3bff7737 384 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 121 198 2.5E-18 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 BWK49_RS04720 4f1433562feb48a0121944da3bff7737 384 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 117 5.9E-22 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS04720 4f1433562feb48a0121944da3bff7737 384 SUPERFAMILY SSF56645 5 241 5.24E-61 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS04720 4f1433562feb48a0121944da3bff7737 384 Gene3D G3DSA:2.40.110.10 121 218 4.2E-27 T 06-07-2017 BWK49_RS04720 4f1433562feb48a0121944da3bff7737 384 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 229 375 5.5E-27 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS04720 4f1433562feb48a0121944da3bff7737 384 Gene3D G3DSA:1.10.540.10 2 119 4.5E-26 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS04720 4f1433562feb48a0121944da3bff7737 384 Gene3D G3DSA:1.20.140.10 219 383 5.3E-47 T 06-07-2017 BWK49_RS21725 227bc122ad519173d551b71e4a0b8532 570 Pfam PF14021 Protein of unknown function (DUF4237) 466 563 2.3E-18 T 06-07-2017 IPR025331 Protein of unknown function DUF4237 BWK49_RS21725 227bc122ad519173d551b71e4a0b8532 570 Gene3D G3DSA:1.10.287.1060 11 83 3.2E-4 T 06-07-2017 BWK49_RS21725 227bc122ad519173d551b71e4a0b8532 570 SUPERFAMILY SSF140453 11 89 2.88E-5 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like BWK49_RS18840 1d332f4f6b57143541bbbc23cc29cfbf 199 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 196 29.271 T 06-07-2017 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 BWK49_RS18840 1d332f4f6b57143541bbbc23cc29cfbf 199 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 192 1.4E-37 T 06-07-2017 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 BWK49_RS18840 1d332f4f6b57143541bbbc23cc29cfbf 199 SMART SM00278 72 91 280.0 T 06-07-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 BWK49_RS18840 1d332f4f6b57143541bbbc23cc29cfbf 199 SMART SM00278 107 126 0.66 T 06-07-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 BWK49_RS18840 1d332f4f6b57143541bbbc23cc29cfbf 199 SUPERFAMILY SSF46929 150 197 2.75E-8 T 06-07-2017 IPR011114 DNA helicase, Holliday junction RuvA type, domain III, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 BWK49_RS18840 1d332f4f6b57143541bbbc23cc29cfbf 199 Gene3D G3DSA:1.10.150.20 68 134 9.7E-26 T 06-07-2017 BWK49_RS18840 1d332f4f6b57143541bbbc23cc29cfbf 199 Pfam PF01330 RuvA N terminal domain 1 61 7.2E-20 T 06-07-2017 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 BWK49_RS18840 1d332f4f6b57143541bbbc23cc29cfbf 199 Pfam PF14520 Helix-hairpin-helix domain 71 129 1.6E-15 T 06-07-2017 BWK49_RS18840 1d332f4f6b57143541bbbc23cc29cfbf 199 SUPERFAMILY SSF47781 65 132 2.3E-19 T 06-07-2017 IPR010994 RuvA domain 2-like BWK49_RS18840 1d332f4f6b57143541bbbc23cc29cfbf 199 Gene3D G3DSA:1.10.8.10 141 199 5.9E-25 T 06-07-2017 BWK49_RS18840 1d332f4f6b57143541bbbc23cc29cfbf 199 Gene3D G3DSA:2.40.50.140 1 63 4.3E-24 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS18840 1d332f4f6b57143541bbbc23cc29cfbf 199 SUPERFAMILY SSF50249 1 62 2.46E-14 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS18840 1d332f4f6b57143541bbbc23cc29cfbf 199 Pfam PF07499 RuvA, C-terminal domain 154 195 3.2E-9 T 06-07-2017 IPR011114 DNA helicase, Holliday junction RuvA type, domain III, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 BWK49_RS20075 3683a417123303ec80e36562b4728ff6 392 Gene3D G3DSA:3.20.20.70 48 212 4.4E-6 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 BWK49_RS20075 3683a417123303ec80e36562b4728ff6 392 SUPERFAMILY SSF56014 276 361 2.09E-11 T 06-07-2017 BWK49_RS20075 3683a417123303ec80e36562b4728ff6 392 PIRSF PIRSF004640 11 373 2.3E-143 T 06-07-2017 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 BWK49_RS20075 3683a417123303ec80e36562b4728ff6 392 SUPERFAMILY SSF51717 46 219 1.8E-9 T 06-07-2017 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 BWK49_RS20075 3683a417123303ec80e36562b4728ff6 392 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 18 360 1.7E-125 T 06-07-2017 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 BWK49_RS20075 3683a417123303ec80e36562b4728ff6 392 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 16 367 33.047 T 06-07-2017 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 BWK49_RS20075 3683a417123303ec80e36562b4728ff6 392 Pfam PF04551 GcpE protein 21 361 1.5E-130 T 06-07-2017 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 BWK49_RS20895 cf1e3b87235decf76ead5ef09dbf1a16 488 Gene3D G3DSA:1.10.1160.10 253 335 2.0E-28 T 06-07-2017 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 BWK49_RS20895 cf1e3b87235decf76ead5ef09dbf1a16 488 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 6 323 9.9E-75 T 06-07-2017 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 BWK49_RS20895 cf1e3b87235decf76ead5ef09dbf1a16 488 Gene3D G3DSA:1.10.10.350 388 483 4.5E-20 T 06-07-2017 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 BWK49_RS20895 cf1e3b87235decf76ead5ef09dbf1a16 488 PRINTS PR00987 Glutamyl-tRNA synthetase signature 210 218 4.1E-22 T 06-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 BWK49_RS20895 cf1e3b87235decf76ead5ef09dbf1a16 488 PRINTS PR00987 Glutamyl-tRNA synthetase signature 24 35 4.1E-22 T 06-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 BWK49_RS20895 cf1e3b87235decf76ead5ef09dbf1a16 488 PRINTS PR00987 Glutamyl-tRNA synthetase signature 10 22 4.1E-22 T 06-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 BWK49_RS20895 cf1e3b87235decf76ead5ef09dbf1a16 488 PRINTS PR00987 Glutamyl-tRNA synthetase signature 39 52 4.1E-22 T 06-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 BWK49_RS20895 cf1e3b87235decf76ead5ef09dbf1a16 488 PRINTS PR00987 Glutamyl-tRNA synthetase signature 194 204 4.1E-22 T 06-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 BWK49_RS20895 cf1e3b87235decf76ead5ef09dbf1a16 488 Hamap MF_00022_B Glutamate--tRNA ligase [gltX]. 7 484 30.9 T 06-07-2017 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 BWK49_RS20895 cf1e3b87235decf76ead5ef09dbf1a16 488 SUPERFAMILY SSF48163 320 483 3.4E-34 T 06-07-2017 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 BWK49_RS20895 cf1e3b87235decf76ead5ef09dbf1a16 488 Gene3D G3DSA:3.40.50.620 196 250 1.7E-43 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold BWK49_RS20895 cf1e3b87235decf76ead5ef09dbf1a16 488 Gene3D G3DSA:3.40.50.620 7 71 1.7E-43 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold BWK49_RS20895 cf1e3b87235decf76ead5ef09dbf1a16 488 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 7 481 1.1E-126 T 06-07-2017 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 BWK49_RS20895 cf1e3b87235decf76ead5ef09dbf1a16 488 SUPERFAMILY SSF52374 7 319 3.22E-96 T 06-07-2017 BWK49_RS20895 cf1e3b87235decf76ead5ef09dbf1a16 488 Gene3D G3DSA:3.90.800.10 72 194 6.5E-34 T 06-07-2017 BWK49_RS11425 9a9feeddaefa232c3b1f860373a0af22 343 TIGRFAM TIGR00331 hrcA: heat-inducible transcription repressor HrcA 5 338 2.2E-88 T 06-07-2017 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 BWK49_RS11425 9a9feeddaefa232c3b1f860373a0af22 343 SUPERFAMILY SSF55781 73 341 2.35E-54 T 06-07-2017 IPR029016 GAF domain-like BWK49_RS11425 9a9feeddaefa232c3b1f860373a0af22 343 PIRSF PIRSF005485 2 343 1.5E-103 T 06-07-2017 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 BWK49_RS11425 9a9feeddaefa232c3b1f860373a0af22 343 Gene3D G3DSA:1.10.10.10 4 86 6.7E-34 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS11425 9a9feeddaefa232c3b1f860373a0af22 343 Pfam PF01628 HrcA protein C terminal domain 105 326 3.9E-61 T 06-07-2017 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 BWK49_RS11425 9a9feeddaefa232c3b1f860373a0af22 343 Gene3D G3DSA:3.30.450.40 178 341 1.5E-34 T 06-07-2017 IPR029016 GAF domain-like BWK49_RS11425 9a9feeddaefa232c3b1f860373a0af22 343 SUPERFAMILY SSF46785 5 84 4.45E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS11425 9a9feeddaefa232c3b1f860373a0af22 343 Hamap MF_00081 Heat-inducible transcription repressor HrcA [hrcA]. 3 333 27.598 T 06-07-2017 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 BWK49_RS28365 b55748e77c0337cfb35589d6d55baac5 246 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 42 213 1.0E-42 T 06-07-2017 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 BWK49_RS28365 b55748e77c0337cfb35589d6d55baac5 246 Pfam PF02527 rRNA small subunit methyltransferase G 41 215 6.0E-54 T 06-07-2017 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 BWK49_RS28365 b55748e77c0337cfb35589d6d55baac5 246 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 30 212 24.045 T 06-07-2017 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 BWK49_RS28365 b55748e77c0337cfb35589d6d55baac5 246 SUPERFAMILY SSF53335 41 216 8.67E-32 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS28365 b55748e77c0337cfb35589d6d55baac5 246 Gene3D G3DSA:3.40.50.150 42 240 4.2E-61 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS18540 229a823d5648a5f7a28e148467d53f60 953 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 563 749 6.5E-22 T 06-07-2017 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 BWK49_RS18540 229a823d5648a5f7a28e148467d53f60 953 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 292 517 8.4E-50 T 06-07-2017 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 BWK49_RS18540 229a823d5648a5f7a28e148467d53f60 953 Gene3D G3DSA:3.40.640.10 553 630 4.2E-95 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 BWK49_RS18540 229a823d5648a5f7a28e148467d53f60 953 Gene3D G3DSA:3.40.640.10 292 514 4.2E-95 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 BWK49_RS18540 229a823d5648a5f7a28e148467d53f60 953 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 842 882 1.9E-4 T 06-07-2017 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 BWK49_RS18540 229a823d5648a5f7a28e148467d53f60 953 Gene3D G3DSA:3.90.1150.10 635 784 3.1E-9 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 BWK49_RS18540 229a823d5648a5f7a28e148467d53f60 953 SUPERFAMILY SSF55904 722 892 1.29E-15 T 06-07-2017 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 BWK49_RS18540 229a823d5648a5f7a28e148467d53f60 953 SUPERFAMILY SSF53383 292 514 1.45E-78 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase BWK49_RS18540 229a823d5648a5f7a28e148467d53f60 953 SUPERFAMILY SSF53383 553 763 1.45E-78 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase BWK49_RS18540 229a823d5648a5f7a28e148467d53f60 953 Gene3D G3DSA:3.90.100.10 849 883 6.6E-8 T 06-07-2017 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 BWK49_RS11150 38b835ddaf1a6abc4025edffa2e11efa 203 SUPERFAMILY SSF55469 2 57 5.1E-40 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 BWK49_RS11150 38b835ddaf1a6abc4025edffa2e11efa 203 SUPERFAMILY SSF55469 90 196 5.1E-40 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 BWK49_RS11150 38b835ddaf1a6abc4025edffa2e11efa 203 Gene3D G3DSA:3.40.109.10 5 193 2.4E-40 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 BWK49_RS11150 38b835ddaf1a6abc4025edffa2e11efa 203 Pfam PF00881 Nitroreductase family 5 172 2.9E-25 T 06-07-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 BWK49_RS19530 21f068b91da694c6259e4751f4061714 475 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 254 274 6.8E-8 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 BWK49_RS19530 21f068b91da694c6259e4751f4061714 475 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 321 339 6.8E-8 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 BWK49_RS19530 21f068b91da694c6259e4751f4061714 475 Hamap MF_00900 GTPase HflX [hflX]. 73 446 48.111 T 06-07-2017 IPR016496 GTPase HflX GO:0005525 BWK49_RS19530 21f068b91da694c6259e4751f4061714 475 Pfam PF13167 GTP-binding GTPase N-terminal 71 158 4.6E-33 T 06-07-2017 IPR025121 GTPase HflX, N-terminal BWK49_RS19530 21f068b91da694c6259e4751f4061714 475 PIRSF PIRSF006809 23 475 1.7E-167 T 06-07-2017 IPR016496 GTPase HflX GO:0005525 BWK49_RS19530 21f068b91da694c6259e4751f4061714 475 Pfam PF16360 GTP-binding GTPase Middle Region 160 246 3.4E-30 T 06-07-2017 IPR032305 GTP-binding protein, middle domain BWK49_RS19530 21f068b91da694c6259e4751f4061714 475 SUPERFAMILY SSF52540 251 421 5.03E-39 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS19530 21f068b91da694c6259e4751f4061714 475 Gene3D G3DSA:3.40.50.300 252 417 1.8E-34 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS19530 21f068b91da694c6259e4751f4061714 475 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 54 415 2.0E-131 T 06-07-2017 IPR016496 GTPase HflX GO:0005525 BWK49_RS19530 21f068b91da694c6259e4751f4061714 475 Pfam PF01926 50S ribosome-binding GTPase 254 376 6.1E-21 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 BWK49_RS06410 21c2d26344dba6f65abacee75ca7b0f5 196 SUPERFAMILY SSF81452 13 195 1.7E-39 T 06-07-2017 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 BWK49_RS06410 21c2d26344dba6f65abacee75ca7b0f5 196 Gene3D G3DSA:1.20.120.80 17 195 5.4E-40 T 06-07-2017 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 BWK49_RS06410 21c2d26344dba6f65abacee75ca7b0f5 196 Pfam PF00510 Cytochrome c oxidase subunit III 19 194 6.9E-11 T 06-07-2017 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 BWK49_RS26040 80720cd31460c1ab4b0e6728f9f28047 343 SUPERFAMILY SSF51569 4 340 3.11E-100 T 06-07-2017 BWK49_RS26040 80720cd31460c1ab4b0e6728f9f28047 343 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 86 97 - T 06-07-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 BWK49_RS26040 80720cd31460c1ab4b0e6728f9f28047 343 PIRSF PIRSF001359 6 341 1.8E-63 T 06-07-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 BWK49_RS26040 80720cd31460c1ab4b0e6728f9f28047 343 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 158 169 - T 06-07-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 BWK49_RS26040 80720cd31460c1ab4b0e6728f9f28047 343 Pfam PF01116 Fructose-bisphosphate aldolase class-II 9 339 2.5E-81 T 06-07-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 BWK49_RS26040 80720cd31460c1ab4b0e6728f9f28047 343 TIGRFAM TIGR01520 FruBisAldo_II_A: fructose-bisphosphate aldolase, class II 3 340 1.2E-152 T 06-07-2017 IPR006411 Fructose-bisphosphate aldolase, class II, yeast/E. coli subtype GO:0004332|GO:0006096 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 BWK49_RS26040 80720cd31460c1ab4b0e6728f9f28047 343 Gene3D G3DSA:3.20.20.70 2 340 1.0E-120 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 BWK49_RS26040 80720cd31460c1ab4b0e6728f9f28047 343 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 10 340 2.1E-74 T 06-07-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 BWK49_RS07125 5a7b42470018c66da1a9c6c1ac7a2023 429 Pfam PF00994 Probable molybdopterin binding domain 198 335 3.1E-18 T 06-07-2017 IPR001453 MoaB/Mog domain BWK49_RS07125 5a7b42470018c66da1a9c6c1ac7a2023 429 SUPERFAMILY SSF63882 2 193 3.14E-40 T 06-07-2017 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 BWK49_RS07125 5a7b42470018c66da1a9c6c1ac7a2023 429 Pfam PF03453 MoeA N-terminal region (domain I and II) 3 184 2.6E-30 T 06-07-2017 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 BWK49_RS07125 5a7b42470018c66da1a9c6c1ac7a2023 429 Pfam PF03454 MoeA C-terminal region (domain IV) 349 425 6.1E-20 T 06-07-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 BWK49_RS07125 5a7b42470018c66da1a9c6c1ac7a2023 429 SUPERFAMILY SSF53218 194 339 7.46E-31 T 06-07-2017 IPR001453 MoaB/Mog domain BWK49_RS07125 5a7b42470018c66da1a9c6c1ac7a2023 429 SUPERFAMILY SSF63867 346 425 3.79E-15 T 06-07-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 BWK49_RS07125 5a7b42470018c66da1a9c6c1ac7a2023 429 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 194 332 7.9E-27 T 06-07-2017 IPR001453 MoaB/Mog domain BWK49_RS07125 5a7b42470018c66da1a9c6c1ac7a2023 429 Gene3D G3DSA:2.40.340.10 350 422 5.1E-18 T 06-07-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 BWK49_RS07125 5a7b42470018c66da1a9c6c1ac7a2023 429 SMART SM00852 197 336 2.3E-20 T 06-07-2017 IPR001453 MoaB/Mog domain BWK49_RS07125 5a7b42470018c66da1a9c6c1ac7a2023 429 Gene3D G3DSA:3.40.980.10 180 349 2.9E-48 T 06-07-2017 IPR001453 MoaB/Mog domain BWK49_RS07125 5a7b42470018c66da1a9c6c1ac7a2023 429 Gene3D G3DSA:3.90.105.10 149 179 2.5E-17 T 06-07-2017 BWK49_RS07125 5a7b42470018c66da1a9c6c1ac7a2023 429 Gene3D G3DSA:2.170.190.11 44 148 4.8E-31 T 06-07-2017 BWK49_RS05740 8b358942e263ceb61e83acce8a98ea79 184 SUPERFAMILY SSF46689 1 70 1.49E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS05740 8b358942e263ceb61e83acce8a98ea79 184 Gene3D G3DSA:1.10.357.10 1 147 4.2E-25 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS05740 8b358942e263ceb61e83acce8a98ea79 184 Pfam PF00440 Bacterial regulatory proteins, tetR family 1 47 2.1E-14 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS05740 8b358942e263ceb61e83acce8a98ea79 184 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 45 1.9E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS05740 8b358942e263ceb61e83acce8a98ea79 184 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 1 14 1.9E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS02280 ef6930c7585e4174d827ebf984e9271b 304 Gene3D G3DSA:3.20.20.60 3 247 2.2E-71 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 BWK49_RS02280 ef6930c7585e4174d827ebf984e9271b 304 PIRSF PIRSF015582 1 304 4.9E-84 T 06-07-2017 IPR011206 Citrate lyase beta subunit-like BWK49_RS02280 ef6930c7585e4174d827ebf984e9271b 304 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 7 236 1.2E-40 T 06-07-2017 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 BWK49_RS02280 ef6930c7585e4174d827ebf984e9271b 304 SUPERFAMILY SSF51621 4 246 1.15E-62 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 BWK49_RS18775 2c612399e98a4481b2b9141bc670e999 792 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 88 787 1.8E-278 T 06-07-2017 IPR004811 RelA/SpoT family GO:0015969 BWK49_RS18775 2c612399e98a4481b2b9141bc670e999 792 Pfam PF04607 Region found in RelA / SpoT proteins 295 404 2.6E-37 T 06-07-2017 IPR007685 RelA/SpoT GO:0015969 BWK49_RS18775 2c612399e98a4481b2b9141bc670e999 792 Gene3D G3DSA:3.30.70.260 713 785 4.0E-13 T 06-07-2017 BWK49_RS18775 2c612399e98a4481b2b9141bc670e999 792 Pfam PF13328 HD domain 88 235 3.4E-46 T 06-07-2017 IPR003607 HD/PDEase domain BWK49_RS18775 2c612399e98a4481b2b9141bc670e999 792 Pfam PF13291 ACT domain 711 787 3.1E-16 T 06-07-2017 IPR002912 ACT domain GO:0008152|GO:0016597 BWK49_RS18775 2c612399e98a4481b2b9141bc670e999 792 SUPERFAMILY SSF55021 710 790 1.5E-14 T 06-07-2017 BWK49_RS18775 2c612399e98a4481b2b9141bc670e999 792 SMART SM00471 103 213 5.5E-13 T 06-07-2017 IPR003607 HD/PDEase domain BWK49_RS18775 2c612399e98a4481b2b9141bc670e999 792 SMART SM00954 295 405 3.0E-60 T 06-07-2017 IPR007685 RelA/SpoT GO:0015969 BWK49_RS18775 2c612399e98a4481b2b9141bc670e999 792 Gene3D G3DSA:3.10.20.30 453 515 5.2E-25 T 06-07-2017 IPR012675 Beta-grasp domain BWK49_RS18775 2c612399e98a4481b2b9141bc670e999 792 SUPERFAMILY SSF109604 63 251 1.02E-68 T 06-07-2017 BWK49_RS18775 2c612399e98a4481b2b9141bc670e999 792 Gene3D G3DSA:3.30.460.10 238 385 2.5E-46 T 06-07-2017 BWK49_RS18775 2c612399e98a4481b2b9141bc670e999 792 SUPERFAMILY SSF81301 240 458 4.41E-60 T 06-07-2017 BWK49_RS18775 2c612399e98a4481b2b9141bc670e999 792 SUPERFAMILY SSF81271 441 513 8.83E-22 T 06-07-2017 IPR012676 TGS-like KEGG: 00970+6.1.1.3 BWK49_RS18775 2c612399e98a4481b2b9141bc670e999 792 Pfam PF02824 TGS domain 454 513 3.1E-23 T 06-07-2017 IPR004095 TGS KEGG: 00970+6.1.1.3 BWK49_RS09735 75697c03bfccd307176b8b9fb53c3c7e 388 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 12 122 2.6E-35 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS09735 75697c03bfccd307176b8b9fb53c3c7e 388 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 237 385 1.1E-48 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS09735 75697c03bfccd307176b8b9fb53c3c7e 388 SUPERFAMILY SSF47203 235 385 1.24E-49 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS09735 75697c03bfccd307176b8b9fb53c3c7e 388 Gene3D G3DSA:2.40.110.10 127 226 2.3E-33 T 06-07-2017 BWK49_RS09735 75697c03bfccd307176b8b9fb53c3c7e 388 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 344 363 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 BWK49_RS09735 75697c03bfccd307176b8b9fb53c3c7e 388 Gene3D G3DSA:1.20.140.10 227 385 1.3E-63 T 06-07-2017 BWK49_RS09735 75697c03bfccd307176b8b9fb53c3c7e 388 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 129 141 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 BWK49_RS09735 75697c03bfccd307176b8b9fb53c3c7e 388 Gene3D G3DSA:1.10.540.10 10 123 2.7E-39 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS09735 75697c03bfccd307176b8b9fb53c3c7e 388 SUPERFAMILY SSF56645 9 250 3.27E-76 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS09735 75697c03bfccd307176b8b9fb53c3c7e 388 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 127 224 3.5E-21 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 BWK49_RS17345 6e69e8546bf03ea27991e61ede298356 286 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 16 286 1.8E-95 T 06-07-2017 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 BWK49_RS17345 6e69e8546bf03ea27991e61ede298356 286 PIRSF PIRSF006250 6 286 1.3E-106 T 06-07-2017 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 BWK49_RS17345 6e69e8546bf03ea27991e61ede298356 286 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 118 285 1.4E-61 T 06-07-2017 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 BWK49_RS17345 6e69e8546bf03ea27991e61ede298356 286 Gene3D G3DSA:3.20.20.70 139 276 1.7E-54 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 BWK49_RS17345 6e69e8546bf03ea27991e61ede298356 286 Gene3D G3DSA:3.90.1170.20 11 138 2.0E-41 T 06-07-2017 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 BWK49_RS17345 6e69e8546bf03ea27991e61ede298356 286 SUPERFAMILY SSF51690 118 286 3.49E-55 T 06-07-2017 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 BWK49_RS17345 6e69e8546bf03ea27991e61ede298356 286 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 28 116 7.3E-21 T 06-07-2017 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 BWK49_RS17345 6e69e8546bf03ea27991e61ede298356 286 SUPERFAMILY SSF54675 8 117 2.24E-28 T 06-07-2017 BWK49_RS23735 634afd3792a77f83c5a0a5079e43fefc 249 SUPERFAMILY SSF56784 10 248 8.86E-38 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS23735 634afd3792a77f83c5a0a5079e43fefc 249 Pfam PF13419 Haloacid dehalogenase-like hydrolase 14 215 1.0E-14 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS23735 634afd3792a77f83c5a0a5079e43fefc 249 Gene3D G3DSA:1.10.150.240 25 116 2.3E-8 T 06-07-2017 IPR023198 Phosphoglycolate phosphatase, domain 2 BWK49_RS23735 634afd3792a77f83c5a0a5079e43fefc 249 TIGRFAM TIGR02009 PGMB-YQAB-SF: beta-phosphoglucomutase family hydrolase 11 219 1.2E-57 T 06-07-2017 IPR010976 Beta-phosphoglucomutase hydrolase BWK49_RS23735 634afd3792a77f83c5a0a5079e43fefc 249 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 175 219 1.8E-8 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 BWK49_RS23735 634afd3792a77f83c5a0a5079e43fefc 249 Gene3D G3DSA:3.40.50.1000 8 24 7.9E-33 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS23735 634afd3792a77f83c5a0a5079e43fefc 249 Gene3D G3DSA:3.40.50.1000 123 247 7.9E-33 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS03120 3d9f9edbd8fc7d4c32dc2c9b0374a80d 847 Gene3D G3DSA:1.10.8.60 352 436 1.6E-34 T 06-07-2017 BWK49_RS03120 3d9f9edbd8fc7d4c32dc2c9b0374a80d 847 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 213 325 4.0E-12 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 BWK49_RS03120 3d9f9edbd8fc7d4c32dc2c9b0374a80d 847 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 16 68 7.9E-18 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 BWK49_RS03120 3d9f9edbd8fc7d4c32dc2c9b0374a80d 847 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 93 142 1.2E-15 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 BWK49_RS03120 3d9f9edbd8fc7d4c32dc2c9b0374a80d 847 Gene3D G3DSA:1.10.8.60 734 806 1.1E-29 T 06-07-2017 BWK49_RS03120 3d9f9edbd8fc7d4c32dc2c9b0374a80d 847 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 623 641 2.0E-38 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 BWK49_RS03120 3d9f9edbd8fc7d4c32dc2c9b0374a80d 847 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 549 567 2.0E-38 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 BWK49_RS03120 3d9f9edbd8fc7d4c32dc2c9b0374a80d 847 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 594 612 2.0E-38 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 BWK49_RS03120 3d9f9edbd8fc7d4c32dc2c9b0374a80d 847 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 656 670 2.0E-38 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 BWK49_RS03120 3d9f9edbd8fc7d4c32dc2c9b0374a80d 847 SMART SM01086 722 818 3.6E-34 T 06-07-2017 IPR019489 Clp ATPase, C-terminal BWK49_RS03120 3d9f9edbd8fc7d4c32dc2c9b0374a80d 847 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 303 315 - T 06-07-2017 IPR018368 ClpA/B, conserved site 1 GO:0005524 BWK49_RS03120 3d9f9edbd8fc7d4c32dc2c9b0374a80d 847 Gene3D G3DSA:3.40.50.300 171 351 1.2E-45 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS03120 3d9f9edbd8fc7d4c32dc2c9b0374a80d 847 SUPERFAMILY SSF81923 3 144 1.37E-31 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 BWK49_RS03120 3d9f9edbd8fc7d4c32dc2c9b0374a80d 847 SUPERFAMILY SSF52540 171 470 2.63E-73 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS03120 3d9f9edbd8fc7d4c32dc2c9b0374a80d 847 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 722 802 2.4E-24 T 06-07-2017 IPR019489 Clp ATPase, C-terminal BWK49_RS03120 3d9f9edbd8fc7d4c32dc2c9b0374a80d 847 SMART SM00382 545 723 7.1E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS03120 3d9f9edbd8fc7d4c32dc2c9b0374a80d 847 SMART SM00382 208 353 9.0E-8 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS03120 3d9f9edbd8fc7d4c32dc2c9b0374a80d 847 Pfam PF07724 AAA domain (Cdc48 subfamily) 544 716 4.3E-50 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 BWK49_RS03120 3d9f9edbd8fc7d4c32dc2c9b0374a80d 847 SUPERFAMILY SSF52540 494 808 5.51E-76 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS03120 3d9f9edbd8fc7d4c32dc2c9b0374a80d 847 Gene3D G3DSA:3.40.50.300 498 669 8.3E-54 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS03120 3d9f9edbd8fc7d4c32dc2c9b0374a80d 847 Gene3D G3DSA:3.40.50.300 703 733 8.3E-54 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS03120 3d9f9edbd8fc7d4c32dc2c9b0374a80d 847 Pfam PF02151 UvrB/uvrC motif 425 459 3.6E-7 T 06-07-2017 IPR001943 UVR domain GO:0005515 BWK49_RS03120 3d9f9edbd8fc7d4c32dc2c9b0374a80d 847 Gene3D G3DSA:1.10.1780.10 1 143 4.6E-52 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 BWK49_RS03515 d27a2e0e2909df27ff2d0ba2e6f23c0a 323 Gene3D G3DSA:2.40.50.140 231 295 6.9E-5 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS03515 d27a2e0e2909df27ff2d0ba2e6f23c0a 323 Gene3D G3DSA:2.40.50.140 74 135 1.4E-4 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS03515 d27a2e0e2909df27ff2d0ba2e6f23c0a 323 SUPERFAMILY SSF50249 163 297 1.1E-30 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS03515 d27a2e0e2909df27ff2d0ba2e6f23c0a 323 SUPERFAMILY SSF50249 4 139 4.28E-28 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS03515 d27a2e0e2909df27ff2d0ba2e6f23c0a 323 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 67 131 3.8E-11 T 06-07-2017 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal BWK49_RS03515 d27a2e0e2909df27ff2d0ba2e6f23c0a 323 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 227 291 3.0E-13 T 06-07-2017 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal BWK49_RS01600 919d80bdd56810b15d546f9ee372d8db 356 SUPERFAMILY SSF46689 18 106 6.45E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS01600 919d80bdd56810b15d546f9ee372d8db 356 Pfam PF00665 Integrase core domain 152 307 1.5E-41 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 BWK49_RS01600 919d80bdd56810b15d546f9ee372d8db 356 Pfam PF13011 leucine-zipper of insertion element IS481 23 103 4.3E-19 T 06-07-2017 IPR024967 DNA-binding domain, IS481-type BWK49_RS01600 919d80bdd56810b15d546f9ee372d8db 356 SUPERFAMILY SSF53098 209 348 5.18E-31 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS01600 919d80bdd56810b15d546f9ee372d8db 356 Gene3D G3DSA:3.30.420.10 212 344 2.5E-40 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS01600 919d80bdd56810b15d546f9ee372d8db 356 Gene3D G3DSA:3.30.420.10 147 176 2.5E-40 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS27815 e21ff803d972c5b69a74c0cd95a0fb48 540 Gene3D G3DSA:3.40.50.980 197 348 5.2E-37 T 06-07-2017 BWK49_RS27815 e21ff803d972c5b69a74c0cd95a0fb48 540 ProSitePatterns PS00455 Putative AMP-binding domain signature. 191 202 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS27815 e21ff803d972c5b69a74c0cd95a0fb48 540 Pfam PF00501 AMP-binding enzyme 31 437 2.7E-71 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS27815 e21ff803d972c5b69a74c0cd95a0fb48 540 Gene3D G3DSA:2.30.38.10 374 431 3.3E-10 T 06-07-2017 BWK49_RS27815 e21ff803d972c5b69a74c0cd95a0fb48 540 Gene3D G3DSA:3.40.50.980 25 196 4.0E-28 T 06-07-2017 BWK49_RS27815 e21ff803d972c5b69a74c0cd95a0fb48 540 Pfam PF13193 AMP-binding enzyme C-terminal domain 446 522 1.2E-16 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS27815 e21ff803d972c5b69a74c0cd95a0fb48 540 Gene3D G3DSA:3.30.300.30 432 531 2.0E-26 T 06-07-2017 BWK49_RS27815 e21ff803d972c5b69a74c0cd95a0fb48 540 SUPERFAMILY SSF56801 22 532 1.05E-117 T 06-07-2017 BWK49_RS14480 227f414e69a3ace705d463e0cc052ca9 394 Gene3D G3DSA:1.20.140.10 211 387 4.0E-36 T 06-07-2017 BWK49_RS14480 227f414e69a3ace705d463e0cc052ca9 394 Gene3D G3DSA:2.40.110.10 120 210 5.2E-19 T 06-07-2017 BWK49_RS14480 227f414e69a3ace705d463e0cc052ca9 394 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 242 373 3.5E-34 T 06-07-2017 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain BWK49_RS14480 227f414e69a3ace705d463e0cc052ca9 394 PIRSF PIRSF016578 1 394 4.6E-111 T 06-07-2017 BWK49_RS14480 227f414e69a3ace705d463e0cc052ca9 394 SUPERFAMILY SSF47203 231 389 1.39E-16 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS14480 227f414e69a3ace705d463e0cc052ca9 394 SUPERFAMILY SSF56645 14 215 1.68E-18 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS14480 227f414e69a3ace705d463e0cc052ca9 394 Gene3D G3DSA:1.10.540.10 3 110 3.7E-21 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS07280 0e1ea9ae3378b8880b91bc9061103566 264 Pfam PF05050 Methyltransferase FkbM domain 56 213 1.2E-16 T 06-07-2017 IPR006342 Methyltransferase FkbM BWK49_RS07280 0e1ea9ae3378b8880b91bc9061103566 264 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 55 192 6.6E-29 T 06-07-2017 IPR006342 Methyltransferase FkbM BWK49_RS07280 0e1ea9ae3378b8880b91bc9061103566 264 Gene3D G3DSA:3.40.50.150 41 229 4.7E-43 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS07280 0e1ea9ae3378b8880b91bc9061103566 264 SUPERFAMILY SSF53335 41 214 4.97E-40 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS23140 559c13de44f729fa478bc86f3f6778f0 406 Gene3D G3DSA:3.30.470.20 153 395 8.8E-84 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 BWK49_RS23140 559c13de44f729fa478bc86f3f6778f0 406 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 3 366 39.177 T 06-07-2017 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 BWK49_RS23140 559c13de44f729fa478bc86f3f6778f0 406 SUPERFAMILY SSF51246 307 394 1.49E-14 T 06-07-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 BWK49_RS23140 559c13de44f729fa478bc86f3f6778f0 406 Pfam PF02222 ATP-grasp domain 109 280 1.5E-54 T 06-07-2017 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type BWK49_RS23140 559c13de44f729fa478bc86f3f6778f0 406 Gene3D G3DSA:3.30.1490.20 101 152 1.5E-7 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 BWK49_RS23140 559c13de44f729fa478bc86f3f6778f0 406 SUPERFAMILY SSF56059 100 301 7.78E-59 T 06-07-2017 BWK49_RS23140 559c13de44f729fa478bc86f3f6778f0 406 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 4 367 6.1E-125 T 06-07-2017 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 BWK49_RS23140 559c13de44f729fa478bc86f3f6778f0 406 Gene3D G3DSA:3.40.50.20 3 100 2.8E-28 T 06-07-2017 IPR016185 Pre-ATP-grasp domain BWK49_RS23140 559c13de44f729fa478bc86f3f6778f0 406 SUPERFAMILY SSF52440 3 95 7.91E-21 T 06-07-2017 IPR016185 Pre-ATP-grasp domain BWK49_RS21040 b976de124952e4df986e235465db4cff 111 Gene3D G3DSA:1.10.10.10 10 107 9.3E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS21040 b976de124952e4df986e235465db4cff 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 1.7E-8 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 BWK49_RS21040 b976de124952e4df986e235465db4cff 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 12 27 1.7E-8 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 BWK49_RS21040 b976de124952e4df986e235465db4cff 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 45 60 1.7E-8 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 BWK49_RS21040 b976de124952e4df986e235465db4cff 111 SMART SM00418 10 88 7.3E-9 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 BWK49_RS21040 b976de124952e4df986e235465db4cff 111 Pfam PF12840 Helix-turn-helix domain 11 69 2.0E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS21040 b976de124952e4df986e235465db4cff 111 SUPERFAMILY SSF46785 9 101 1.46E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS06880 7be6fa5586e1b96e192c40461714876c 300 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 99 291 2.0E-23 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS06880 7be6fa5586e1b96e192c40461714876c 300 SUPERFAMILY SSF161098 34 288 1.5E-39 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS06880 7be6fa5586e1b96e192c40461714876c 300 Gene3D G3DSA:1.10.3720.10 29 291 6.7E-41 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS06880 7be6fa5586e1b96e192c40461714876c 300 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 29 292 4.6E-76 T 06-07-2017 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 BWK49_RS09795 33c1f75679d0006fecd2d2d4892034e2 784 SUPERFAMILY SSF69593 260 442 5.36E-9 T 06-07-2017 BWK49_RS09795 33c1f75679d0006fecd2d2d4892034e2 784 PIRSF PIRSF000437 4 779 1.0E-177 T 06-07-2017 IPR022284 Glycerol-3-phosphate O-acyltransferase/Dihydroxyacetone phosphate acyltransferase GO:0008374|GO:0044255 KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587|Reactome: R-HSA-1483166 BWK49_RS09795 33c1f75679d0006fecd2d2d4892034e2 784 Pfam PF01553 Acyltransferase 258 387 3.0E-14 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 BWK49_RS09795 33c1f75679d0006fecd2d2d4892034e2 784 PIRSF PIRSF500064 1 779 5.8E-188 T 06-07-2017 IPR028354 Glycerol-3-phosphate acyltransferase, PlsB GO:0004366|GO:0005886|GO:0008654 KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587|Reactome: R-HSA-1483166|Reactome: R-HSA-2426168|Reactome: R-HSA-75109 BWK49_RS09795 33c1f75679d0006fecd2d2d4892034e2 784 SMART SM00563 262 389 7.7E-15 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 BWK49_RS11870 661633c1d272949c71cd86df4ab25663 229 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 2.0E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS11870 661633c1d272949c71cd86df4ab25663 229 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 2.0E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS11870 661633c1d272949c71cd86df4ab25663 229 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 65 2.2E-14 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS11870 661633c1d272949c71cd86df4ab25663 229 SUPERFAMILY SSF46689 6 84 7.7E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS11870 661633c1d272949c71cd86df4ab25663 229 SUPERFAMILY SSF48498 94 180 6.67E-7 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS11870 661633c1d272949c71cd86df4ab25663 229 Gene3D G3DSA:1.10.357.10 2 201 5.9E-30 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS21870 b3035859551e2c27660caeed9aca849d 557 Pfam PF07730 Histidine kinase 366 426 1.3E-11 T 06-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 BWK49_RS21870 b3035859551e2c27660caeed9aca849d 557 Gene3D G3DSA:3.30.565.10 455 548 2.2E-9 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS21870 b3035859551e2c27660caeed9aca849d 557 SUPERFAMILY SSF55874 449 554 1.31E-17 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS21870 b3035859551e2c27660caeed9aca849d 557 Gene3D G3DSA:3.30.450.40 197 359 1.7E-17 T 06-07-2017 IPR029016 GAF domain-like BWK49_RS21870 b3035859551e2c27660caeed9aca849d 557 SUPERFAMILY SSF55781 30 213 9.6E-38 T 06-07-2017 IPR029016 GAF domain-like BWK49_RS21870 b3035859551e2c27660caeed9aca849d 557 Gene3D G3DSA:3.30.450.40 30 194 3.0E-29 T 06-07-2017 IPR029016 GAF domain-like BWK49_RS21870 b3035859551e2c27660caeed9aca849d 557 Pfam PF13185 GAF domain 216 348 4.1E-8 T 06-07-2017 IPR003018 GAF domain GO:0005515 BWK49_RS21870 b3035859551e2c27660caeed9aca849d 557 Pfam PF13185 GAF domain 48 186 5.4E-15 T 06-07-2017 IPR003018 GAF domain GO:0005515 BWK49_RS21870 b3035859551e2c27660caeed9aca849d 557 SUPERFAMILY SSF55781 197 376 8.29E-18 T 06-07-2017 IPR029016 GAF domain-like BWK49_RS21870 b3035859551e2c27660caeed9aca849d 557 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 472 519 7.3E-9 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS21870 b3035859551e2c27660caeed9aca849d 557 SMART SM00387 467 557 3.4E-13 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS21870 b3035859551e2c27660caeed9aca849d 557 SMART SM00065 216 358 2.4E-6 T 06-07-2017 IPR003018 GAF domain GO:0005515 BWK49_RS21870 b3035859551e2c27660caeed9aca849d 557 SMART SM00065 48 195 1.0E-23 T 06-07-2017 IPR003018 GAF domain GO:0005515 BWK49_RS07080 49e3ad3a75c45a5278dee4d1dcbb8bb2 520 Gene3D G3DSA:1.10.287.130 233 311 6.8E-13 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 BWK49_RS07080 49e3ad3a75c45a5278dee4d1dcbb8bb2 520 SMART SM00387 355 470 1.6E-34 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS07080 49e3ad3a75c45a5278dee4d1dcbb8bb2 520 SUPERFAMILY SSF47384 226 316 1.8E-13 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 BWK49_RS07080 49e3ad3a75c45a5278dee4d1dcbb8bb2 520 SUPERFAMILY SSF55874 305 468 5.24E-35 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS07080 49e3ad3a75c45a5278dee4d1dcbb8bb2 520 Gene3D G3DSA:3.30.565.10 319 470 3.7E-36 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS07080 49e3ad3a75c45a5278dee4d1dcbb8bb2 520 PRINTS PR00344 Bacterial sensor protein C-terminal signature 426 444 1.3E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 BWK49_RS07080 49e3ad3a75c45a5278dee4d1dcbb8bb2 520 PRINTS PR00344 Bacterial sensor protein C-terminal signature 393 407 1.3E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 BWK49_RS07080 49e3ad3a75c45a5278dee4d1dcbb8bb2 520 PRINTS PR00344 Bacterial sensor protein C-terminal signature 411 421 1.3E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 BWK49_RS07080 49e3ad3a75c45a5278dee4d1dcbb8bb2 520 PRINTS PR00344 Bacterial sensor protein C-terminal signature 454 467 1.3E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 BWK49_RS07080 49e3ad3a75c45a5278dee4d1dcbb8bb2 520 SUPERFAMILY SSF158472 193 239 1.44E-6 T 06-07-2017 BWK49_RS07080 49e3ad3a75c45a5278dee4d1dcbb8bb2 520 SMART SM00304 190 242 8.9E-12 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 BWK49_RS07080 49e3ad3a75c45a5278dee4d1dcbb8bb2 520 Pfam PF00512 His Kinase A (phospho-acceptor) domain 244 315 8.5E-12 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 BWK49_RS07080 49e3ad3a75c45a5278dee4d1dcbb8bb2 520 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 355 467 9.3E-21 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS07080 49e3ad3a75c45a5278dee4d1dcbb8bb2 520 Pfam PF00672 HAMP domain 170 238 8.2E-15 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 BWK49_RS07080 49e3ad3a75c45a5278dee4d1dcbb8bb2 520 SMART SM00388 243 315 1.4E-13 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 Gene3D G3DSA:3.40.50.980 5090 5240 1.0E-42 T 06-07-2017 BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 Pfam PF00501 AMP-binding enzyme 464 849 5.0E-89 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 Pfam PF00501 AMP-binding enzyme 5097 5482 2.7E-85 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 Pfam PF00501 AMP-binding enzyme 4044 4429 1.0E-86 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 Pfam PF00501 AMP-binding enzyme 1521 1923 7.2E-89 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 Pfam PF00501 AMP-binding enzyme 2585 2973 2.4E-84 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 ProSitePatterns PS00012 Phosphopantetheine attachment site. 4556 4571 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 SUPERFAMILY SSF52777 2113 2288 2.33E-47 T 06-07-2017 BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3504 3519 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 Pfam PF00975 Thioesterase domain 5673 5902 3.5E-26 T 06-07-2017 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 SUPERFAMILY SSF56801 5055 5599 2.62E-142 T 06-07-2017 BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 Gene3D G3DSA:3.40.50.980 1515 1669 5.0E-45 T 06-07-2017 BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 Gene3D G3DSA:3.40.50.980 2580 2747 4.3E-41 T 06-07-2017 BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 Gene3D G3DSA:3.40.50.980 459 611 1.1E-48 T 06-07-2017 BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 Gene3D G3DSA:3.40.50.980 4039 4191 1.2E-43 T 06-07-2017 BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 SUPERFAMILY SSF47336 5578 5651 3.66E-18 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 Pfam PF00668 Condensation domain 1039 1341 6.0E-64 T 06-07-2017 IPR001242 Condensation domain BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 Pfam PF00668 Condensation domain 2 291 4.0E-30 T 06-07-2017 IPR001242 Condensation domain BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 Pfam PF00668 Condensation domain 3562 3864 1.3E-59 T 06-07-2017 IPR001242 Condensation domain BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 Pfam PF00668 Condensation domain 4615 4917 1.4E-64 T 06-07-2017 IPR001242 Condensation domain BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 Pfam PF00668 Condensation domain 2110 2411 8.7E-59 T 06-07-2017 IPR001242 Condensation domain BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 SMART SM00823 Phosphopantetheine attachment site 2027 2096 2.0E-6 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 SMART SM00823 Phosphopantetheine attachment site 4532 4601 4.2E-7 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 SMART SM00823 Phosphopantetheine attachment site 956 1025 3.3E-8 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 SMART SM00823 Phosphopantetheine attachment site 3477 3549 9.4E-8 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 SMART SM00823 Phosphopantetheine attachment site 5586 5655 1.1E-5 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 SUPERFAMILY SSF52777 1 174 6.56E-29 T 06-07-2017 BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 Gene3D G3DSA:3.40.50.1820 5667 5773 6.7E-42 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 Gene3D G3DSA:3.40.50.1820 5845 5908 6.7E-42 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 SUPERFAMILY SSF56801 2543 3026 6.54E-146 T 06-07-2017 BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 SUPERFAMILY SSF56801 3418 3492 6.54E-146 T 06-07-2017 BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 SUPERFAMILY SSF53335 3033 3204 1.67E-23 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 SUPERFAMILY SSF52777 3565 3740 1.11E-44 T 06-07-2017 BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 Gene3D G3DSA:3.30.300.30 844 959 3.0E-39 T 06-07-2017 BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 Gene3D G3DSA:3.30.300.30 1918 2031 1.2E-37 T 06-07-2017 BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 Gene3D G3DSA:3.30.300.30 2969 3024 9.7E-36 T 06-07-2017 BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 Gene3D G3DSA:3.30.300.30 3423 3483 9.7E-36 T 06-07-2017 BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 Gene3D G3DSA:3.30.300.30 5477 5590 2.8E-37 T 06-07-2017 BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 Gene3D G3DSA:3.30.300.30 4424 4535 1.2E-38 T 06-07-2017 BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 SUPERFAMILY SSF52777 3751 4005 1.22E-52 T 06-07-2017 BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1660 1671 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 SUPERFAMILY SSF47336 2019 2092 2.09E-19 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 ProSitePatterns PS00012 Phosphopantetheine attachment site. 5610 5625 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 485 873 3.3E-128 T 06-07-2017 IPR010071 Amino acid adenylation domain BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 5117 5506 1.7E-128 T 06-07-2017 IPR010071 Amino acid adenylation domain BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1542 1947 1.2E-131 T 06-07-2017 IPR010071 Amino acid adenylation domain BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 4065 4453 4.0E-126 T 06-07-2017 IPR010071 Amino acid adenylation domain BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2604 2996 3.6E-118 T 06-07-2017 IPR010071 Amino acid adenylation domain BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 Pfam PF08241 Methyltransferase domain 3088 3189 3.8E-12 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 SUPERFAMILY SSF52777 182 425 1.05E-22 T 06-07-2017 BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 ProSitePatterns PS00012 Phosphopantetheine attachment site. 980 995 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 ProSitePatterns PS00455 Putative AMP-binding domain signature. 4183 4194 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 Gene3D G3DSA:3.40.50.150 3070 3197 2.4E-20 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 SUPERFAMILY SSF52777 4805 5060 8.23E-57 T 06-07-2017 BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 ProSitePatterns PS00455 Putative AMP-binding domain signature. 603 614 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 SUPERFAMILY SSF52777 2301 2547 4.11E-56 T 06-07-2017 BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 SUPERFAMILY SSF56801 4007 4545 2.49E-139 T 06-07-2017 BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 SUPERFAMILY SSF47336 948 1019 6.02E-19 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 SUPERFAMILY SSF52777 1042 1217 4.56E-49 T 06-07-2017 BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 Gene3D G3DSA:3.40.50.980 2751 2885 4.8E-34 T 06-07-2017 BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 SUPERFAMILY SSF52777 1229 1485 1.22E-55 T 06-07-2017 BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 Pfam PF00550 Phosphopantetheine attachment site 3483 3542 3.0E-13 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 Pfam PF00550 Phosphopantetheine attachment site 2030 2089 1.1E-12 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 Pfam PF00550 Phosphopantetheine attachment site 959 1018 1.7E-13 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 Pfam PF00550 Phosphopantetheine attachment site 4535 4594 1.6E-13 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 Pfam PF00550 Phosphopantetheine attachment site 5589 5650 1.2E-12 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 SUPERFAMILY SSF56801 423 969 4.45E-145 T 06-07-2017 BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 SUPERFAMILY SSF56801 1477 2040 1.44E-146 T 06-07-2017 BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 SUPERFAMILY SSF47336 3473 3545 2.36E-19 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 SUPERFAMILY SSF53474 5668 5908 1.52E-43 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 SUPERFAMILY SSF47336 4524 4594 1.96E-18 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 SMART SM01294 957 1021 0.0041 T 06-07-2017 BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 Gene3D G3DSA:2.30.38.10 5394 5471 2.2E-22 T 06-07-2017 BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 Gene3D G3DSA:2.30.38.10 4341 4418 2.0E-22 T 06-07-2017 BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 Gene3D G3DSA:2.30.38.10 1835 1912 4.0E-20 T 06-07-2017 BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 Gene3D G3DSA:2.30.38.10 761 838 2.1E-22 T 06-07-2017 BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 Gene3D G3DSA:2.30.38.10 2886 2962 9.6E-25 T 06-07-2017 BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2051 2066 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 Pfam PF13193 AMP-binding enzyme C-terminal domain 1931 2002 3.3E-11 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 Pfam PF13193 AMP-binding enzyme C-terminal domain 5490 5561 3.3E-11 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 Pfam PF13193 AMP-binding enzyme C-terminal domain 857 932 1.8E-10 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 Pfam PF13193 AMP-binding enzyme C-terminal domain 4437 4508 6.4E-11 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 SUPERFAMILY SSF52777 4618 4793 8.56E-48 T 06-07-2017 BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 Gene3D G3DSA:1.10.1200.10 960 1023 1.5E-24 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 Gene3D G3DSA:1.10.1200.10 5591 5653 1.0E-23 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 Gene3D G3DSA:1.10.1200.10 3484 3547 3.6E-25 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 Gene3D G3DSA:1.10.1200.10 2032 2093 2.3E-25 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 Gene3D G3DSA:1.10.1200.10 4536 4597 3.8E-25 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2727 2738 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 Pfam PF13745 HxxPF-repeated domain 2435 2530 8.9E-30 T 06-07-2017 BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 Pfam PF13745 HxxPF-repeated domain 1363 1463 6.0E-27 T 06-07-2017 BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 Pfam PF13745 HxxPF-repeated domain 4939 5040 5.9E-27 T 06-07-2017 BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 Pfam PF13745 HxxPF-repeated domain 3886 3985 3.7E-24 T 06-07-2017 BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 Gene3D G3DSA:3.40.50.980 5241 5393 6.0E-38 T 06-07-2017 BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 Gene3D G3DSA:3.40.50.980 612 760 7.8E-36 T 06-07-2017 BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 Gene3D G3DSA:3.40.50.980 4192 4340 2.3E-35 T 06-07-2017 BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 Gene3D G3DSA:3.40.50.980 1670 1834 3.2E-44 T 06-07-2017 BWK49_RS13220 c3243354e99cb7e2345f59e4ad40dd40 5920 ProSitePatterns PS00455 Putative AMP-binding domain signature. 5235 5246 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS22580 c423f865b8f5aea22ef9f69894dd0b85 117 Gene3D G3DSA:3.40.109.10 1 46 6.5E-11 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 BWK49_RS22580 c423f865b8f5aea22ef9f69894dd0b85 117 SUPERFAMILY SSF55469 47 92 6.12E-6 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 BWK49_RS22580 c423f865b8f5aea22ef9f69894dd0b85 117 Gene3D G3DSA:3.40.109.10 47 93 2.2E-4 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 BWK49_RS22580 c423f865b8f5aea22ef9f69894dd0b85 117 Pfam PF00881 Nitroreductase family 11 46 1.1E-6 T 06-07-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 BWK49_RS22580 c423f865b8f5aea22ef9f69894dd0b85 117 SUPERFAMILY SSF55469 1 46 9.42E-11 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 BWK49_RS07685 898711b7e672d4a821d54240b44a6df1 217 SUPERFAMILY SSF46689 13 77 1.49E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS07685 898711b7e672d4a821d54240b44a6df1 217 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 71 4.1E-12 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS07685 898711b7e672d4a821d54240b44a6df1 217 Gene3D G3DSA:1.10.357.10 78 202 1.5E-36 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS07685 898711b7e672d4a821d54240b44a6df1 217 Gene3D G3DSA:1.10.10.60 12 71 1.3E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS07685 898711b7e672d4a821d54240b44a6df1 217 SUPERFAMILY SSF48498 91 201 1.4E-27 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS04595 1882881d2400bdbd8d46c124e7f19d4e 344 Pfam PF00665 Integrase core domain 186 291 2.4E-10 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 BWK49_RS04595 1882881d2400bdbd8d46c124e7f19d4e 344 Gene3D G3DSA:3.30.420.10 186 330 1.4E-8 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS04595 1882881d2400bdbd8d46c124e7f19d4e 344 ProSitePatterns PS01043 Transposases, IS30 family, signature. 278 294 - T 06-07-2017 IPR001598 Transposase, IS30, conserved site GO:0003677|GO:0004803|GO:0006313 BWK49_RS04595 1882881d2400bdbd8d46c124e7f19d4e 344 SUPERFAMILY SSF53098 186 332 9.86E-21 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS04595 1882881d2400bdbd8d46c124e7f19d4e 344 Pfam PF13936 Helix-turn-helix domain 7 48 6.3E-16 T 06-07-2017 IPR025246 Transposase IS30-like HTH domain BWK49_RS06345 8b826b3a29a633b0ca30008577da4930 384 Pfam PF02470 MlaD protein 26 102 1.2E-9 T 06-07-2017 IPR003399 Mce/MlaD BWK49_RS06345 8b826b3a29a633b0ca30008577da4930 384 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 132 347 6.1E-57 T 06-07-2017 IPR024516 Mammalian cell entry, C-terminal BWK49_RS06345 8b826b3a29a633b0ca30008577da4930 384 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 2 279 4.0E-62 T 06-07-2017 IPR005693 Virulence factor Mce protein BWK49_RS27830 678291f9fffb3dfa1c76e01ff563d476 380 TIGRFAM TIGR03989 Rxyl_3153: NDMA-dependent alcohol dehydrogenase, Rxyl_3153 family 1 377 2.3E-146 T 06-07-2017 IPR023921 Alcohol dehydrogenase, zinc-type, actinomycetes KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396 BWK49_RS27830 678291f9fffb3dfa1c76e01ff563d476 380 SUPERFAMILY SSF50129 329 376 1.93E-8 T 06-07-2017 IPR011032 GroES-like BWK49_RS27830 678291f9fffb3dfa1c76e01ff563d476 380 SUPERFAMILY SSF50129 1 200 3.2E-51 T 06-07-2017 IPR011032 GroES-like BWK49_RS27830 678291f9fffb3dfa1c76e01ff563d476 380 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 68 82 - T 06-07-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 BWK49_RS27830 678291f9fffb3dfa1c76e01ff563d476 380 Pfam PF00107 Zinc-binding dehydrogenase 204 325 1.5E-18 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 BWK49_RS27830 678291f9fffb3dfa1c76e01ff563d476 380 SUPERFAMILY SSF51735 166 341 1.06E-33 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS27830 678291f9fffb3dfa1c76e01ff563d476 380 Gene3D G3DSA:3.40.50.720 197 312 3.6E-26 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS27830 678291f9fffb3dfa1c76e01ff563d476 380 SMART SM00829 4 375 2.4E-4 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 BWK49_RS27830 678291f9fffb3dfa1c76e01ff563d476 380 Gene3D G3DSA:3.90.180.10 1 196 2.6E-53 T 06-07-2017 IPR011032 GroES-like BWK49_RS27830 678291f9fffb3dfa1c76e01ff563d476 380 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 22 162 4.9E-26 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 BWK49_RS28320 8f03f4d53133d976551553d7b7b05c00 1189 PRINTS PR01806 Virulence factor MviN signature 155 179 2.9E-15 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ BWK49_RS28320 8f03f4d53133d976551553d7b7b05c00 1189 PRINTS PR01806 Virulence factor MviN signature 291 317 2.9E-15 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ BWK49_RS28320 8f03f4d53133d976551553d7b7b05c00 1189 PRINTS PR01806 Virulence factor MviN signature 179 200 2.9E-15 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ BWK49_RS28320 8f03f4d53133d976551553d7b7b05c00 1189 PRINTS PR01806 Virulence factor MviN signature 389 408 2.9E-15 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ BWK49_RS28320 8f03f4d53133d976551553d7b7b05c00 1189 PRINTS PR01806 Virulence factor MviN signature 77 93 2.9E-15 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ BWK49_RS28320 8f03f4d53133d976551553d7b7b05c00 1189 PRINTS PR01806 Virulence factor MviN signature 58 77 2.9E-15 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ BWK49_RS28320 8f03f4d53133d976551553d7b7b05c00 1189 Gene3D G3DSA:3.30.200.20 703 783 2.2E-4 T 06-07-2017 BWK49_RS28320 8f03f4d53133d976551553d7b7b05c00 1189 SUPERFAMILY SSF56112 707 879 1.42E-6 T 06-07-2017 IPR011009 Protein kinase-like domain BWK49_RS28320 8f03f4d53133d976551553d7b7b05c00 1189 Pfam PF03023 MviN-like protein 54 525 1.3E-117 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ BWK49_RS28320 8f03f4d53133d976551553d7b7b05c00 1189 Gene3D G3DSA:2.60.120.260 1054 1182 1.5E-4 T 06-07-2017 IPR008979 Galactose-binding domain-like BWK49_RS08605 4a02902d1c2f0df879fdbb5889aee72b 364 SUPERFAMILY SSF143865 27 296 3.27E-62 T 06-07-2017 BWK49_RS08605 4a02902d1c2f0df879fdbb5889aee72b 364 Gene3D G3DSA:1.20.58.340 175 286 1.1E-32 T 06-07-2017 BWK49_RS08605 4a02902d1c2f0df879fdbb5889aee72b 364 SUPERFAMILY SSF144083 299 361 1.57E-18 T 06-07-2017 BWK49_RS08605 4a02902d1c2f0df879fdbb5889aee72b 364 TIGRFAM TIGR00383 corA: magnesium and cobalt transport protein CorA 62 364 7.3E-61 T 06-07-2017 IPR004488 Magnesium/cobalt transport protein CorA GO:0006824|GO:0015087|GO:0015095|GO:0015693|GO:0016020 BWK49_RS08605 4a02902d1c2f0df879fdbb5889aee72b 364 Gene3D G3DSA:3.30.460.20 16 174 1.1E-42 T 06-07-2017 BWK49_RS08605 4a02902d1c2f0df879fdbb5889aee72b 364 Gene3D G3DSA:1.20.58.340 288 364 4.5E-24 T 06-07-2017 BWK49_RS08605 4a02902d1c2f0df879fdbb5889aee72b 364 Pfam PF01544 CorA-like Mg2+ transporter protein 66 359 9.9E-62 T 06-07-2017 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 BWK49_RS05780 ac6f1db61f20e7c2c194a925f74dffdc 525 Gene3D G3DSA:3.20.20.240 6 518 8.4E-204 T 06-07-2017 IPR014348 Cobalamin (vitamin B12)-dependent enzyme, catalytic subdomain GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 BWK49_RS05780 ac6f1db61f20e7c2c194a925f74dffdc 525 Pfam PF01642 Methylmalonyl-CoA mutase 7 517 6.8E-198 T 06-07-2017 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 BWK49_RS05780 ac6f1db61f20e7c2c194a925f74dffdc 525 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 6 522 6.0E-199 T 06-07-2017 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 BWK49_RS05780 ac6f1db61f20e7c2c194a925f74dffdc 525 SUPERFAMILY SSF51703 4 519 2.75E-188 T 06-07-2017 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 BWK49_RS03965 e35ab8a524f0c5b12dda098fbeb20b39 484 PIRSF PIRSF000350 2 475 6.2E-65 T 06-07-2017 BWK49_RS03965 e35ab8a524f0c5b12dda098fbeb20b39 484 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 363 469 3.7E-20 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 BWK49_RS03965 e35ab8a524f0c5b12dda098fbeb20b39 484 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 42 57 5.5E-49 T 06-07-2017 BWK49_RS03965 e35ab8a524f0c5b12dda098fbeb20b39 484 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 310 317 5.5E-49 T 06-07-2017 BWK49_RS03965 e35ab8a524f0c5b12dda098fbeb20b39 484 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 359 380 5.5E-49 T 06-07-2017 BWK49_RS03965 e35ab8a524f0c5b12dda098fbeb20b39 484 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 179 204 5.5E-49 T 06-07-2017 BWK49_RS03965 e35ab8a524f0c5b12dda098fbeb20b39 484 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 265 279 5.5E-49 T 06-07-2017 BWK49_RS03965 e35ab8a524f0c5b12dda098fbeb20b39 484 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 448 468 5.5E-49 T 06-07-2017 BWK49_RS03965 e35ab8a524f0c5b12dda098fbeb20b39 484 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 10 32 5.5E-49 T 06-07-2017 BWK49_RS03965 e35ab8a524f0c5b12dda098fbeb20b39 484 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 426 441 5.5E-49 T 06-07-2017 BWK49_RS03965 e35ab8a524f0c5b12dda098fbeb20b39 484 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 143 152 5.5E-49 T 06-07-2017 BWK49_RS03965 e35ab8a524f0c5b12dda098fbeb20b39 484 SUPERFAMILY SSF51905 6 338 8.43E-41 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS03965 e35ab8a524f0c5b12dda098fbeb20b39 484 Gene3D G3DSA:3.50.50.60 8 150 3.4E-25 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS03965 e35ab8a524f0c5b12dda098fbeb20b39 484 Gene3D G3DSA:3.30.390.30 355 477 1.3E-26 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 BWK49_RS03965 e35ab8a524f0c5b12dda098fbeb20b39 484 SUPERFAMILY SSF55424 361 478 6.87E-26 T 06-07-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 BWK49_RS03965 e35ab8a524f0c5b12dda098fbeb20b39 484 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 140 158 4.2E-18 T 06-07-2017 BWK49_RS03965 e35ab8a524f0c5b12dda098fbeb20b39 484 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 4.2E-18 T 06-07-2017 BWK49_RS03965 e35ab8a524f0c5b12dda098fbeb20b39 484 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 264 280 4.2E-18 T 06-07-2017 BWK49_RS03965 e35ab8a524f0c5b12dda098fbeb20b39 484 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 179 197 4.2E-18 T 06-07-2017 BWK49_RS03965 e35ab8a524f0c5b12dda098fbeb20b39 484 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 9 323 2.7E-43 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS03965 e35ab8a524f0c5b12dda098fbeb20b39 484 Gene3D G3DSA:3.50.50.60 151 337 1.0E-32 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS00425 5b75b0dd136c48d33b15d8486ad62535 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 66 2.2E-31 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 BWK49_RS00425 5b75b0dd136c48d33b15d8486ad62535 67 PRINTS PR00050 Cold shock protein signature 25 34 7.5E-17 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 BWK49_RS00425 5b75b0dd136c48d33b15d8486ad62535 67 PRINTS PR00050 Cold shock protein signature 4 19 7.5E-17 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 BWK49_RS00425 5b75b0dd136c48d33b15d8486ad62535 67 PRINTS PR00050 Cold shock protein signature 40 58 7.5E-17 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 BWK49_RS00425 5b75b0dd136c48d33b15d8486ad62535 67 Gene3D G3DSA:2.40.50.140 1 65 3.5E-31 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS00425 5b75b0dd136c48d33b15d8486ad62535 67 SMART SM00357 3 67 5.6E-30 T 06-07-2017 IPR011129 Cold shock protein GO:0003676 BWK49_RS00425 5b75b0dd136c48d33b15d8486ad62535 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 06-07-2017 IPR019844 Cold-shock conserved site BWK49_RS00425 5b75b0dd136c48d33b15d8486ad62535 67 PIRSF PIRSF002599 1 67 7.6E-25 T 06-07-2017 IPR012156 Cold shock, CspA GO:0003676 BWK49_RS00425 5b75b0dd136c48d33b15d8486ad62535 67 SUPERFAMILY SSF50249 1 66 2.79E-25 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS24595 c1fca0d8b73bec84cccf84db17c2a2c1 151 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 96 151 2.1E-21 T 06-07-2017 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 BWK49_RS24595 c1fca0d8b73bec84cccf84db17c2a2c1 151 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 97 147 2.6E-18 T 06-07-2017 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 BWK49_RS24595 c1fca0d8b73bec84cccf84db17c2a2c1 151 ProSitePatterns PS01067 Protein secE/sec61-gamma signature. 98 126 - T 06-07-2017 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 BWK49_RS24595 c1fca0d8b73bec84cccf84db17c2a2c1 151 Gene3D G3DSA:1.20.5.1030 96 150 1.9E-20 T 06-07-2017 BWK49_RS24595 c1fca0d8b73bec84cccf84db17c2a2c1 151 Hamap MF_00422 Protein translocase subunit SecE [secE]. 93 148 12.588 T 06-07-2017 IPR022943 Preprotein translocase subunit SecE Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 BWK49_RS08185 30970988fdbd6dc2b24fef901f90c009 121 Gene3D G3DSA:1.10.10.10 9 81 4.8E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS08185 30970988fdbd6dc2b24fef901f90c009 121 Pfam PF00392 Bacterial regulatory proteins, gntR family 20 80 3.6E-14 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 BWK49_RS08185 30970988fdbd6dc2b24fef901f90c009 121 SUPERFAMILY SSF46785 11 92 3.41E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS08185 30970988fdbd6dc2b24fef901f90c009 121 SMART SM00345 21 80 2.7E-12 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 BWK49_RS07760 143d37b7fa725e32e3e8ee15c1a43ce7 671 PIRSF PIRSF006402 1 670 3.4E-191 T 06-07-2017 IPR024705 Spermatogenesis-associated protein 20 BWK49_RS07760 143d37b7fa725e32e3e8ee15c1a43ce7 671 SUPERFAMILY SSF52833 8 137 5.9E-27 T 06-07-2017 IPR012336 Thioredoxin-like fold BWK49_RS07760 143d37b7fa725e32e3e8ee15c1a43ce7 671 Gene3D G3DSA:3.40.30.10 27 148 5.1E-31 T 06-07-2017 IPR012336 Thioredoxin-like fold BWK49_RS07760 143d37b7fa725e32e3e8ee15c1a43ce7 671 Pfam PF07221 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) 466 505 0.0017 T 06-07-2017 BWK49_RS07760 143d37b7fa725e32e3e8ee15c1a43ce7 671 Pfam PF07221 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) 223 309 0.0018 T 06-07-2017 BWK49_RS07760 143d37b7fa725e32e3e8ee15c1a43ce7 671 SUPERFAMILY SSF48208 195 530 1.45E-69 T 06-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 BWK49_RS07760 143d37b7fa725e32e3e8ee15c1a43ce7 671 Pfam PF03190 Protein of unknown function, DUF255 10 164 1.7E-67 T 06-07-2017 IPR004879 Domain of unknown function DUF255 BWK49_RS07760 143d37b7fa725e32e3e8ee15c1a43ce7 671 Gene3D G3DSA:1.50.10.10 212 522 1.0E-23 T 06-07-2017 IPR012341 Six-hairpin glycosidase GO:0003824 BWK49_RS04005 a60ddc54ac5c311fafe8f638d92a6549 567 Pfam PF00970 Oxidoreductase FAD-binding domain 234 330 3.9E-7 T 06-07-2017 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 BWK49_RS04005 a60ddc54ac5c311fafe8f638d92a6549 567 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 495 559 1.9E-5 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 BWK49_RS04005 a60ddc54ac5c311fafe8f638d92a6549 567 PRINTS PR00409 Phthalate dioxygenase reductase family signature 340 359 7.7E-10 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 BWK49_RS04005 a60ddc54ac5c311fafe8f638d92a6549 567 PRINTS PR00409 Phthalate dioxygenase reductase family signature 318 332 7.7E-10 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 BWK49_RS04005 a60ddc54ac5c311fafe8f638d92a6549 567 PRINTS PR00409 Phthalate dioxygenase reductase family signature 282 296 7.7E-10 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 BWK49_RS04005 a60ddc54ac5c311fafe8f638d92a6549 567 PRINTS PR00409 Phthalate dioxygenase reductase family signature 423 431 7.7E-10 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 BWK49_RS04005 a60ddc54ac5c311fafe8f638d92a6549 567 SUPERFAMILY SSF54292 446 567 3.93E-17 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 BWK49_RS04005 a60ddc54ac5c311fafe8f638d92a6549 567 Pfam PF03473 MOSC domain 52 161 2.9E-18 T 06-07-2017 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 BWK49_RS04005 a60ddc54ac5c311fafe8f638d92a6549 567 SUPERFAMILY SSF52343 333 457 3.14E-29 T 06-07-2017 BWK49_RS04005 a60ddc54ac5c311fafe8f638d92a6549 567 SUPERFAMILY SSF63380 228 330 1.36E-27 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 BWK49_RS04005 a60ddc54ac5c311fafe8f638d92a6549 567 SUPERFAMILY SSF50800 2 212 4.39E-63 T 06-07-2017 IPR011037 Pyruvate kinase-like, insert domain BWK49_RS04005 a60ddc54ac5c311fafe8f638d92a6549 567 Gene3D G3DSA:2.40.33.20 2 212 1.3E-69 T 06-07-2017 IPR015808 Molybdenum cofactor sulfurase, C-terminal-like BWK49_RS04005 a60ddc54ac5c311fafe8f638d92a6549 567 Pfam PF03475 3-alpha domain 172 212 7.7E-13 T 06-07-2017 IPR005163 3-alpha domain BWK49_RS04005 a60ddc54ac5c311fafe8f638d92a6549 567 Pfam PF00175 Oxidoreductase NAD-binding domain 343 437 2.0E-6 T 06-07-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 BWK49_RS04005 a60ddc54ac5c311fafe8f638d92a6549 567 Gene3D G3DSA:3.40.50.80 332 453 1.4E-25 T 06-07-2017 BWK49_RS04005 a60ddc54ac5c311fafe8f638d92a6549 567 Gene3D G3DSA:3.10.20.30 454 566 2.5E-18 T 06-07-2017 IPR012675 Beta-grasp domain BWK49_RS04005 a60ddc54ac5c311fafe8f638d92a6549 567 Gene3D G3DSA:2.40.30.10 228 331 9.7E-29 T 06-07-2017 BWK49_RS20500 f383a64046a432f4493a041800497f79 478 Gene3D G3DSA:3.40.50.300 208 446 7.8E-20 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS20500 f383a64046a432f4493a041800497f79 478 Pfam PF01580 FtsK/SpoIIIE family 223 397 1.0E-17 T 06-07-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 BWK49_RS20500 f383a64046a432f4493a041800497f79 478 SUPERFAMILY SSF52540 196 446 7.3E-20 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS23670 253e971726bc0a3960908ada21776800 517 Pfam PF00817 impB/mucB/samB family 9 137 5.0E-12 T 06-07-2017 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 BWK49_RS23670 253e971726bc0a3960908ada21776800 517 SUPERFAMILY SSF56672 15 221 2.4E-32 T 06-07-2017 BWK49_RS23670 253e971726bc0a3960908ada21776800 517 Gene3D G3DSA:1.10.150.20 179 221 1.5E-5 T 06-07-2017 BWK49_RS28445 6d176ec98c545efb48ced9d3a6afb169 431 Gene3D G3DSA:2.40.37.10 208 219 7.4E-23 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 BWK49_RS28445 6d176ec98c545efb48ced9d3a6afb169 431 Gene3D G3DSA:2.40.37.10 260 420 7.4E-23 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 BWK49_RS28445 6d176ec98c545efb48ced9d3a6afb169 431 SUPERFAMILY SSF50621 281 419 8.89E-14 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 BWK49_RS28445 6d176ec98c545efb48ced9d3a6afb169 431 SUPERFAMILY SSF51419 6 215 1.02E-38 T 06-07-2017 IPR029066 PLP-binding barrel BWK49_RS28445 6d176ec98c545efb48ced9d3a6afb169 431 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 160 173 2.0E-7 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 BWK49_RS28445 6d176ec98c545efb48ced9d3a6afb169 431 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 39 57 2.0E-7 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 BWK49_RS28445 6d176ec98c545efb48ced9d3a6afb169 431 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 59 71 2.0E-7 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 BWK49_RS28445 6d176ec98c545efb48ced9d3a6afb169 431 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 282 301 2.0E-7 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 BWK49_RS28445 6d176ec98c545efb48ced9d3a6afb169 431 Gene3D G3DSA:3.20.20.10 15 207 7.4E-39 T 06-07-2017 IPR029066 PLP-binding barrel BWK49_RS28445 6d176ec98c545efb48ced9d3a6afb169 431 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 29 218 1.1E-19 T 06-07-2017 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 BWK49_RS20405 c4bd2e127db28a4b53d5aa4afa055ed1 235 Gene3D G3DSA:1.10.1520.10 17 150 5.8E-40 T 06-07-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 BWK49_RS20405 c4bd2e127db28a4b53d5aa4afa055ed1 235 Gene3D G3DSA:3.30.160.20 159 227 4.8E-25 T 06-07-2017 IPR014720 Double-stranded RNA-binding domain BWK49_RS20405 c4bd2e127db28a4b53d5aa4afa055ed1 235 SMART SM00535 18 154 3.3E-55 T 06-07-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 BWK49_RS20405 c4bd2e127db28a4b53d5aa4afa055ed1 235 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 11 225 3.3E-69 T 06-07-2017 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 BWK49_RS20405 c4bd2e127db28a4b53d5aa4afa055ed1 235 Pfam PF14622 Ribonuclease-III-like 17 143 3.3E-34 T 06-07-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 BWK49_RS20405 c4bd2e127db28a4b53d5aa4afa055ed1 235 SMART SM00358 161 227 1.3E-22 T 06-07-2017 IPR014720 Double-stranded RNA-binding domain BWK49_RS20405 c4bd2e127db28a4b53d5aa4afa055ed1 235 Hamap MF_00104 Ribonuclease 3 [rnc]. 7 223 28.827 T 06-07-2017 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 BWK49_RS20405 c4bd2e127db28a4b53d5aa4afa055ed1 235 Pfam PF00035 Double-stranded RNA binding motif 161 225 1.4E-15 T 06-07-2017 IPR014720 Double-stranded RNA-binding domain BWK49_RS20405 c4bd2e127db28a4b53d5aa4afa055ed1 235 SUPERFAMILY SSF69065 6 162 3.14E-42 T 06-07-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 BWK49_RS20405 c4bd2e127db28a4b53d5aa4afa055ed1 235 SUPERFAMILY SSF54768 115 229 1.24E-26 T 06-07-2017 BWK49_RS20405 c4bd2e127db28a4b53d5aa4afa055ed1 235 ProSitePatterns PS00517 Ribonuclease III family signature. 40 48 - T 06-07-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 BWK49_RS26840 fb9da53bea167c7debafc41eec8f1420 237 Pfam PF12840 Helix-turn-helix domain 16 67 2.7E-6 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS26840 fb9da53bea167c7debafc41eec8f1420 237 SUPERFAMILY SSF46785 14 211 1.16E-9 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS26840 fb9da53bea167c7debafc41eec8f1420 237 Gene3D G3DSA:1.10.10.10 6 92 3.1E-8 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS04320 e7ad34ddb0171adaf3389a355cc1182c 105 Pfam PF10824 Excreted virulence factor EspC, type VII ESX diderm 6 99 2.5E-8 T 06-07-2017 IPR022536 ESX-1 secretion-associated protein EspC BWK49_RS01995 51132358b781854ab5fc11661a195f97 198 ProSitePatterns PS01081 TetR-type HTH domain signature. 37 68 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site BWK49_RS01995 51132358b781854ab5fc11661a195f97 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 68 4.2E-13 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS01995 51132358b781854ab5fc11661a195f97 198 Pfam PF16859 Bacterial transcriptional repressor C-terminal 82 189 2.3E-24 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS01995 51132358b781854ab5fc11661a195f97 198 Gene3D G3DSA:1.10.357.10 67 189 2.1E-25 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS01995 51132358b781854ab5fc11661a195f97 198 Gene3D G3DSA:1.10.10.60 16 66 1.1E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS01995 51132358b781854ab5fc11661a195f97 198 SUPERFAMILY SSF46689 21 76 7.48E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS01995 51132358b781854ab5fc11661a195f97 198 SUPERFAMILY SSF48498 86 192 4.45E-16 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS17655 64f60a7e642ca9c3854f3b4072b4042e 257 TIGRFAM TIGR02623 G1P_cyt_trans: glucose-1-phosphate cytidylyltransferase 1 256 3.1E-140 T 06-07-2017 IPR013446 Glucose-1-phosphate cytidylyltransferase GO:0047343 KEGG: 00500+2.7.7.33|KEGG: 00520+2.7.7.33|MetaCyc: PWY-5833|MetaCyc: PWY-5940 BWK49_RS17655 64f60a7e642ca9c3854f3b4072b4042e 257 Pfam PF00483 Nucleotidyl transferase 2 200 6.3E-17 T 06-07-2017 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 BWK49_RS17655 64f60a7e642ca9c3854f3b4072b4042e 257 Gene3D G3DSA:3.90.550.10 1 255 4.4E-64 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases BWK49_RS17655 64f60a7e642ca9c3854f3b4072b4042e 257 SUPERFAMILY SSF53448 1 256 3.68E-68 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases BWK49_RS26090 3d8dcbc539587874c1f8ceae541ab959 848 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 7 840 0.0 T 06-07-2017 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0016485 BWK49_RS26090 3d8dcbc539587874c1f8ceae541ab959 848 Gene3D G3DSA:1.10.8.60 769 844 1.7E-29 T 06-07-2017 BWK49_RS26090 3d8dcbc539587874c1f8ceae541ab959 848 Gene3D G3DSA:3.40.50.300 556 768 2.5E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS26090 3d8dcbc539587874c1f8ceae541ab959 848 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 757 835 1.1E-25 T 06-07-2017 IPR019489 Clp ATPase, C-terminal BWK49_RS26090 3d8dcbc539587874c1f8ceae541ab959 848 SUPERFAMILY SSF81923 7 155 1.08E-35 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 BWK49_RS26090 3d8dcbc539587874c1f8ceae541ab959 848 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 203 317 2.9E-12 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 BWK49_RS26090 3d8dcbc539587874c1f8ceae541ab959 848 Pfam PF07724 AAA domain (Cdc48 subfamily) 598 749 4.3E-50 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 BWK49_RS26090 3d8dcbc539587874c1f8ceae541ab959 848 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 295 307 - T 06-07-2017 IPR018368 ClpA/B, conserved site 1 GO:0005524 BWK49_RS26090 3d8dcbc539587874c1f8ceae541ab959 848 Gene3D G3DSA:1.10.1780.10 6 147 2.5E-39 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 BWK49_RS26090 3d8dcbc539587874c1f8ceae541ab959 848 SUPERFAMILY SSF52540 157 547 3.51E-97 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS26090 3d8dcbc539587874c1f8ceae541ab959 848 Gene3D G3DSA:3.40.50.300 159 342 5.8E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS26090 3d8dcbc539587874c1f8ceae541ab959 848 Gene3D G3DSA:1.10.8.60 344 428 1.5E-35 T 06-07-2017 BWK49_RS26090 3d8dcbc539587874c1f8ceae541ab959 848 SUPERFAMILY SSF52540 548 838 1.8E-77 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS26090 3d8dcbc539587874c1f8ceae541ab959 848 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 94 145 1.0E-11 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 BWK49_RS26090 3d8dcbc539587874c1f8ceae541ab959 848 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 68 2.8E-12 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 BWK49_RS26090 3d8dcbc539587874c1f8ceae541ab959 848 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 710 724 3.2E-42 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 BWK49_RS26090 3d8dcbc539587874c1f8ceae541ab959 848 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 603 621 3.2E-42 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 BWK49_RS26090 3d8dcbc539587874c1f8ceae541ab959 848 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 648 666 3.2E-42 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 BWK49_RS26090 3d8dcbc539587874c1f8ceae541ab959 848 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 677 695 3.2E-42 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 BWK49_RS26090 3d8dcbc539587874c1f8ceae541ab959 848 SMART SM01086 756 847 2.9E-35 T 06-07-2017 IPR019489 Clp ATPase, C-terminal BWK49_RS26090 3d8dcbc539587874c1f8ceae541ab959 848 SMART SM00382 599 757 2.2E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS26090 3d8dcbc539587874c1f8ceae541ab959 848 SMART SM00382 198 344 4.7E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS26090 3d8dcbc539587874c1f8ceae541ab959 848 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 633 651 - T 06-07-2017 IPR028299 ClpA/B, conserved site 2 BWK49_RS11475 2592597546cc030805abb5331ebabcd6 265 Gene3D G3DSA:2.40.50.140 1 80 2.5E-39 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS11475 2592597546cc030805abb5331ebabcd6 265 Pfam PF02565 Recombination protein O C terminal 85 237 1.0E-29 T 06-07-2017 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 BWK49_RS11475 2592597546cc030805abb5331ebabcd6 265 Hamap MF_00201 DNA repair protein RecO [recO]. 2 243 24.744 T 06-07-2017 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 BWK49_RS11475 2592597546cc030805abb5331ebabcd6 265 Pfam PF11967 Recombination protein O N terminal 1 79 6.4E-27 T 06-07-2017 IPR022572 DNA replication/recombination mediator RecO, N-terminal BWK49_RS11475 2592597546cc030805abb5331ebabcd6 265 TIGRFAM TIGR00613 reco: DNA repair protein RecO 5 186 1.6E-28 T 06-07-2017 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 BWK49_RS11475 2592597546cc030805abb5331ebabcd6 265 SUPERFAMILY SSF57863 82 232 5.23E-36 T 06-07-2017 BWK49_RS11475 2592597546cc030805abb5331ebabcd6 265 SUPERFAMILY SSF50249 1 79 1.64E-20 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS05235 d561b9c79cd7ff74448f002a52014570 485 PRINTS PR00385 P450 superfamily signature 424 433 1.7E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS05235 d561b9c79cd7ff74448f002a52014570 485 PRINTS PR00385 P450 superfamily signature 433 444 1.7E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS05235 d561b9c79cd7ff74448f002a52014570 485 PRINTS PR00385 P450 superfamily signature 297 314 1.7E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS05235 d561b9c79cd7ff74448f002a52014570 485 PRINTS PR00385 P450 superfamily signature 348 359 1.7E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS05235 d561b9c79cd7ff74448f002a52014570 485 Pfam PF00067 Cytochrome P450 61 459 3.8E-67 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS05235 d561b9c79cd7ff74448f002a52014570 485 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 426 435 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 BWK49_RS05235 d561b9c79cd7ff74448f002a52014570 485 SUPERFAMILY SSF48264 53 485 2.23E-95 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS05235 d561b9c79cd7ff74448f002a52014570 485 PRINTS PR00465 E-class P450 group IV signature 376 390 1.6E-20 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS05235 d561b9c79cd7ff74448f002a52014570 485 PRINTS PR00465 E-class P450 group IV signature 55 72 1.6E-20 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS05235 d561b9c79cd7ff74448f002a52014570 485 PRINTS PR00465 E-class P450 group IV signature 433 451 1.6E-20 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS05235 d561b9c79cd7ff74448f002a52014570 485 PRINTS PR00465 E-class P450 group IV signature 392 410 1.6E-20 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS05235 d561b9c79cd7ff74448f002a52014570 485 PRINTS PR00465 E-class P450 group IV signature 343 359 1.6E-20 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS05235 d561b9c79cd7ff74448f002a52014570 485 PRINTS PR00465 E-class P450 group IV signature 417 433 1.6E-20 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS05235 d561b9c79cd7ff74448f002a52014570 485 PRINTS PR00465 E-class P450 group IV signature 288 314 1.6E-20 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS05235 d561b9c79cd7ff74448f002a52014570 485 Gene3D G3DSA:1.10.630.10 54 485 2.5E-98 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS19685 a0314e41762103130167b0c395be9c37 161 PIRSF PIRSF000194 1 161 2.3E-46 T 06-07-2017 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 BWK49_RS19685 a0314e41762103130167b0c395be9c37 161 Pfam PF00186 Dihydrofolate reductase 2 161 4.9E-44 T 06-07-2017 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0006545|GO:0009165|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 BWK49_RS19685 a0314e41762103130167b0c395be9c37 161 SUPERFAMILY SSF53597 2 161 2.87E-47 T 06-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 BWK49_RS19685 a0314e41762103130167b0c395be9c37 161 Gene3D G3DSA:3.40.430.10 2 161 2.2E-51 T 06-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 BWK49_RS19685 a0314e41762103130167b0c395be9c37 161 PRINTS PR00070 Dihydrofolate reductase signature 12 22 1.2E-15 T 06-07-2017 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 BWK49_RS19685 a0314e41762103130167b0c395be9c37 161 PRINTS PR00070 Dihydrofolate reductase signature 93 107 1.2E-15 T 06-07-2017 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 BWK49_RS19685 a0314e41762103130167b0c395be9c37 161 PRINTS PR00070 Dihydrofolate reductase signature 26 34 1.2E-15 T 06-07-2017 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 BWK49_RS19685 a0314e41762103130167b0c395be9c37 161 PRINTS PR00070 Dihydrofolate reductase signature 39 50 1.2E-15 T 06-07-2017 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 BWK49_RS19685 a0314e41762103130167b0c395be9c37 161 ProSitePatterns PS00075 Dihydrofolate reductase (DHFR) domain signature. 12 34 - T 06-07-2017 IPR017925 Dihydrofolate reductase conserved site GO:0004146|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-113510|Reactome: R-HSA-1474151|Reactome: R-HSA-196757|Reactome: R-HSA-69205 BWK49_RS17895 98e95bc76c75139552936229deff863a 244 SUPERFAMILY SSF54001 111 230 2.09E-31 T 06-07-2017 BWK49_RS17895 98e95bc76c75139552936229deff863a 244 Pfam PF00877 NlpC/P60 family 127 241 8.3E-31 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain BWK49_RS17895 98e95bc76c75139552936229deff863a 244 Gene3D G3DSA:3.90.1720.10 109 230 1.5E-37 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain BWK49_RS07400 2974a38d6409a0b908a0531cc9dd2ad9 514 PRINTS PR01041 Methionyl-tRNA synthetase signature 86 97 3.2E-34 T 06-07-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 BWK49_RS07400 2974a38d6409a0b908a0531cc9dd2ad9 514 PRINTS PR01041 Methionyl-tRNA synthetase signature 6 19 3.2E-34 T 06-07-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 BWK49_RS07400 2974a38d6409a0b908a0531cc9dd2ad9 514 PRINTS PR01041 Methionyl-tRNA synthetase signature 226 237 3.2E-34 T 06-07-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 BWK49_RS07400 2974a38d6409a0b908a0531cc9dd2ad9 514 PRINTS PR01041 Methionyl-tRNA synthetase signature 38 52 3.2E-34 T 06-07-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 BWK49_RS07400 2974a38d6409a0b908a0531cc9dd2ad9 514 PRINTS PR01041 Methionyl-tRNA synthetase signature 351 362 3.2E-34 T 06-07-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 BWK49_RS07400 2974a38d6409a0b908a0531cc9dd2ad9 514 PRINTS PR01041 Methionyl-tRNA synthetase signature 259 274 3.2E-34 T 06-07-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 BWK49_RS07400 2974a38d6409a0b908a0531cc9dd2ad9 514 SUPERFAMILY SSF47323 352 510 2.43E-36 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 BWK49_RS07400 2974a38d6409a0b908a0531cc9dd2ad9 514 Hamap MF_01228 Methionine--tRNA ligase [metG]. 1 512 47.394 T 06-07-2017 IPR023457 Methionine-tRNA synthetase, type 2 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 BWK49_RS07400 2974a38d6409a0b908a0531cc9dd2ad9 514 Gene3D G3DSA:2.170.220.10 115 227 4.9E-44 T 06-07-2017 BWK49_RS07400 2974a38d6409a0b908a0531cc9dd2ad9 514 Pfam PF09334 tRNA synthetases class I (M) 4 363 7.2E-110 T 06-07-2017 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 BWK49_RS07400 2974a38d6409a0b908a0531cc9dd2ad9 514 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 4 487 6.3E-149 T 06-07-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 BWK49_RS07400 2974a38d6409a0b908a0531cc9dd2ad9 514 Gene3D G3DSA:3.40.50.620 2 112 7.9E-76 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold BWK49_RS07400 2974a38d6409a0b908a0531cc9dd2ad9 514 Gene3D G3DSA:3.40.50.620 228 338 7.9E-76 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold BWK49_RS07400 2974a38d6409a0b908a0531cc9dd2ad9 514 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 13 22 - T 06-07-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 BWK49_RS07400 2974a38d6409a0b908a0531cc9dd2ad9 514 Gene3D G3DSA:1.10.730.10 340 510 6.0E-52 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 BWK49_RS07400 2974a38d6409a0b908a0531cc9dd2ad9 514 SUPERFAMILY SSF52374 3 354 7.24E-111 T 06-07-2017 BWK49_RS00165 733c4c9e94d2c7e7398f2dfafd85cb8e 195 SUPERFAMILY SSF55729 5 193 1.69E-48 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase BWK49_RS00165 733c4c9e94d2c7e7398f2dfafd85cb8e 195 Pfam PF13523 Acetyltransferase (GNAT) domain 38 180 6.1E-41 T 06-07-2017 BWK49_RS00165 733c4c9e94d2c7e7398f2dfafd85cb8e 195 SMART SM01006 31 79 2.8E-12 T 06-07-2017 IPR019432 Siderophore biosynthesis protein, conserved domain BWK49_RS00165 733c4c9e94d2c7e7398f2dfafd85cb8e 195 Gene3D G3DSA:3.40.630.30 16 192 7.1E-45 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase BWK49_RS18265 33cba9bee66d60416307b13a9ec88c79 339 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 330 2.1E-135 T 06-07-2017 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 BWK49_RS18265 33cba9bee66d60416307b13a9ec88c79 339 SUPERFAMILY SSF51735 2 157 2.24E-57 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS18265 33cba9bee66d60416307b13a9ec88c79 339 Gene3D G3DSA:3.30.360.10 167 320 1.6E-75 T 06-07-2017 BWK49_RS18265 33cba9bee66d60416307b13a9ec88c79 339 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 163 318 1.6E-69 T 06-07-2017 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 BWK49_RS18265 33cba9bee66d60416307b13a9ec88c79 339 SMART SM00846 3 158 8.9E-85 T 06-07-2017 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 BWK49_RS18265 33cba9bee66d60416307b13a9ec88c79 339 Gene3D G3DSA:3.40.50.720 2 166 1.3E-69 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS18265 33cba9bee66d60416307b13a9ec88c79 339 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 116 129 3.9E-38 T 06-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 BWK49_RS18265 33cba9bee66d60416307b13a9ec88c79 339 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 152 170 3.9E-38 T 06-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 BWK49_RS18265 33cba9bee66d60416307b13a9ec88c79 339 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 275 290 3.9E-38 T 06-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 BWK49_RS18265 33cba9bee66d60416307b13a9ec88c79 339 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 235 252 3.9E-38 T 06-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 BWK49_RS18265 33cba9bee66d60416307b13a9ec88c79 339 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 179 195 3.9E-38 T 06-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 BWK49_RS18265 33cba9bee66d60416307b13a9ec88c79 339 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 158 6.8E-55 T 06-07-2017 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 BWK49_RS18265 33cba9bee66d60416307b13a9ec88c79 339 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 156 163 - T 06-07-2017 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 BWK49_RS18265 33cba9bee66d60416307b13a9ec88c79 339 SUPERFAMILY SSF55347 157 318 6.55E-73 T 06-07-2017 BWK49_RS18265 33cba9bee66d60416307b13a9ec88c79 339 PIRSF PIRSF000149 1 338 5.0E-132 T 06-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 BWK49_RS06465 691c5ec64f5304d79ce40cdce0d8e482 571 SUPERFAMILY SSF52518 20 199 5.89E-40 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS06465 691c5ec64f5304d79ce40cdce0d8e482 571 SUPERFAMILY SSF52518 376 562 3.04E-47 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS06465 691c5ec64f5304d79ce40cdce0d8e482 571 Gene3D G3DSA:3.40.50.970 20 197 4.4E-75 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS06465 691c5ec64f5304d79ce40cdce0d8e482 571 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 223 322 2.4E-10 T 06-07-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 BWK49_RS06465 691c5ec64f5304d79ce40cdce0d8e482 571 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 21 194 2.3E-31 T 06-07-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 BWK49_RS06465 691c5ec64f5304d79ce40cdce0d8e482 571 PIRSF PIRSF036565 15 566 8.2E-202 T 06-07-2017 IPR012110 Thiamine pyrophosphate (TPP)-dependent enzyme GO:0016831 BWK49_RS06465 691c5ec64f5304d79ce40cdce0d8e482 571 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 435 454 - T 06-07-2017 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 BWK49_RS06465 691c5ec64f5304d79ce40cdce0d8e482 571 Gene3D G3DSA:3.40.50.1220 206 360 1.9E-37 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain BWK49_RS06465 691c5ec64f5304d79ce40cdce0d8e482 571 Gene3D G3DSA:3.40.50.970 369 558 1.6E-56 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS06465 691c5ec64f5304d79ce40cdce0d8e482 571 SUPERFAMILY SSF52467 184 352 9.16E-22 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain BWK49_RS06465 691c5ec64f5304d79ce40cdce0d8e482 571 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 413 545 6.5E-20 T 06-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 BWK49_RS10245 2485e55ffcac1efad336e03a28f4819b 360 Gene3D G3DSA:2.40.50.100 282 331 4.0E-5 T 06-07-2017 BWK49_RS10245 2485e55ffcac1efad336e03a28f4819b 360 SUPERFAMILY SSF50331 219 332 9.14E-8 T 06-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal BWK49_RS10245 2485e55ffcac1efad336e03a28f4819b 360 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 BWK49_RS10245 2485e55ffcac1efad336e03a28f4819b 360 SUPERFAMILY SSF52540 13 249 1.86E-85 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS10245 2485e55ffcac1efad336e03a28f4819b 360 Gene3D G3DSA:3.40.50.300 12 243 8.6E-82 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS10245 2485e55ffcac1efad336e03a28f4819b 360 TIGRFAM TIGR00968 3a0106s01: sulfate ABC transporter, ATP-binding protein 13 249 5.2E-128 T 06-07-2017 IPR005666 Sulphate transport system permease protein 1 GO:0006810|GO:0016020|GO:0042626 KEGG: 00920+3.6.3.25 BWK49_RS10245 2485e55ffcac1efad336e03a28f4819b 360 SMART SM00382 37 220 1.0E-16 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS10245 2485e55ffcac1efad336e03a28f4819b 360 Pfam PF00005 ABC transporter 28 170 1.4E-35 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 BWK49_RS10245 2485e55ffcac1efad336e03a28f4819b 360 Pfam PF12857 TOBE-like domain 282 333 1.8E-9 T 06-07-2017 IPR024765 TOBE-like domain KEGG: 00920+3.6.3.25 BWK49_RS22770 aaad2c919b9438228592f6cb7d7fe6ae 220 SUPERFAMILY SSF88946 23 120 5.49E-23 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS22770 aaad2c919b9438228592f6cb7d7fe6ae 220 Gene3D G3DSA:1.10.10.10 142 201 2.4E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS22770 aaad2c919b9438228592f6cb7d7fe6ae 220 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 41 197 9.4E-25 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS22770 aaad2c919b9438228592f6cb7d7fe6ae 220 Pfam PF04542 Sigma-70 region 2 41 103 1.8E-17 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS22770 aaad2c919b9438228592f6cb7d7fe6ae 220 TIGRFAM TIGR02947 SigH_actino: RNA polymerase sigma-70 factor, TIGR02947 family 23 211 3.1E-107 T 06-07-2017 IPR014293 RNA polymerase sigma-70, actinobacteria GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS22770 aaad2c919b9438228592f6cb7d7fe6ae 220 SUPERFAMILY SSF88659 144 199 2.06E-16 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS22770 aaad2c919b9438228592f6cb7d7fe6ae 220 Gene3D G3DSA:1.10.1740.10 30 105 2.0E-25 T 06-07-2017 BWK49_RS22770 aaad2c919b9438228592f6cb7d7fe6ae 220 Pfam PF08281 Sigma-70, region 4 144 195 5.5E-16 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS22770 aaad2c919b9438228592f6cb7d7fe6ae 220 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 58 89 - T 06-07-2017 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS19905 8a6584308c90ca18de7657b6c1a980e8 321 SUPERFAMILY SSF64182 19 307 1.03E-52 T 06-07-2017 BWK49_RS19905 8a6584308c90ca18de7657b6c1a980e8 321 Pfam PF02272 DHHA1 domain 260 317 5.2E-6 T 06-07-2017 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 BWK49_RS19905 8a6584308c90ca18de7657b6c1a980e8 321 Gene3D G3DSA:3.90.1640.10 19 198 3.5E-22 T 06-07-2017 BWK49_RS19905 8a6584308c90ca18de7657b6c1a980e8 321 Pfam PF01368 DHH family 20 161 1.5E-12 T 06-07-2017 IPR001667 DDH domain BWK49_RS20250 45fb9101d092eacf83f8a9bf9bdb37e3 772 PIRSF PIRSF000144 5 769 0.0 T 06-07-2017 IPR010046 Oxidoreductase alpha (molybdopterin) subunit GO:0008863|GO:0030151|GO:0051539 BWK49_RS20250 45fb9101d092eacf83f8a9bf9bdb37e3 772 Gene3D G3DSA:3.40.228.10 194 400 2.0E-53 T 06-07-2017 BWK49_RS20250 45fb9101d092eacf83f8a9bf9bdb37e3 772 SUPERFAMILY SSF50692 642 766 4.75E-16 T 06-07-2017 IPR009010 Aspartate decarboxylase-like domain BWK49_RS20250 45fb9101d092eacf83f8a9bf9bdb37e3 772 Pfam PF00384 Molybdopterin oxidoreductase 120 497 2.3E-24 T 06-07-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS20250 45fb9101d092eacf83f8a9bf9bdb37e3 772 Pfam PF01568 Molydopterin dinucleotide binding domain 648 754 1.0E-7 T 06-07-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 BWK49_RS20250 45fb9101d092eacf83f8a9bf9bdb37e3 772 Gene3D G3DSA:3.40.50.740 120 193 4.9E-53 T 06-07-2017 BWK49_RS20250 45fb9101d092eacf83f8a9bf9bdb37e3 772 Gene3D G3DSA:3.40.50.740 401 633 4.9E-53 T 06-07-2017 BWK49_RS20250 45fb9101d092eacf83f8a9bf9bdb37e3 772 SUPERFAMILY SSF53706 57 637 3.01E-139 T 06-07-2017 BWK49_RS20250 45fb9101d092eacf83f8a9bf9bdb37e3 772 TIGRFAM TIGR01701 Fdhalpha-like: oxidoreductase alpha (molybdopterin) subunit 22 765 0.0 T 06-07-2017 IPR010046 Oxidoreductase alpha (molybdopterin) subunit GO:0008863|GO:0030151|GO:0051539 BWK49_RS20250 45fb9101d092eacf83f8a9bf9bdb37e3 772 Gene3D G3DSA:2.40.40.20 642 768 1.2E-10 T 06-07-2017 BWK49_RS06725 f7b937a2b4ff29216e95e3aa0169c7ea 236 Pfam PF00072 Response regulator receiver domain 13 123 1.9E-28 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 BWK49_RS06725 f7b937a2b4ff29216e95e3aa0169c7ea 236 Gene3D G3DSA:3.40.50.2300 9 134 9.0E-41 T 06-07-2017 BWK49_RS06725 f7b937a2b4ff29216e95e3aa0169c7ea 236 SMART SM00862 158 233 7.9E-27 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 BWK49_RS06725 f7b937a2b4ff29216e95e3aa0169c7ea 236 SUPERFAMILY SSF52172 9 184 4.07E-41 T 06-07-2017 IPR011006 CheY-like superfamily BWK49_RS06725 f7b937a2b4ff29216e95e3aa0169c7ea 236 Pfam PF00486 Transcriptional regulatory protein, C terminal 160 233 2.2E-25 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 BWK49_RS06725 f7b937a2b4ff29216e95e3aa0169c7ea 236 Gene3D G3DSA:1.10.10.10 135 234 1.5E-33 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS06725 f7b937a2b4ff29216e95e3aa0169c7ea 236 SMART SM00448 11 122 1.8E-41 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 BWK49_RS09380 4b8ad2932a2154bf8237010d741e6888 550 Gene3D G3DSA:3.30.300.30 451 547 3.1E-26 T 06-07-2017 BWK49_RS09380 4b8ad2932a2154bf8237010d741e6888 550 Pfam PF13193 AMP-binding enzyme C-terminal domain 462 537 3.0E-17 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS09380 4b8ad2932a2154bf8237010d741e6888 550 SUPERFAMILY SSF56801 7 549 4.19E-97 T 06-07-2017 BWK49_RS09380 4b8ad2932a2154bf8237010d741e6888 550 Gene3D G3DSA:3.40.50.980 10 190 9.7E-32 T 06-07-2017 BWK49_RS09380 4b8ad2932a2154bf8237010d741e6888 550 Gene3D G3DSA:2.30.38.10 368 446 3.3E-4 T 06-07-2017 BWK49_RS09380 4b8ad2932a2154bf8237010d741e6888 550 ProSitePatterns PS00455 Putative AMP-binding domain signature. 186 197 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS09380 4b8ad2932a2154bf8237010d741e6888 550 Pfam PF00501 AMP-binding enzyme 17 452 6.8E-47 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS09380 4b8ad2932a2154bf8237010d741e6888 550 Gene3D G3DSA:3.40.50.980 191 363 1.5E-21 T 06-07-2017 BWK49_RS13520 b92039c2949b1d65d4c9c20b5be30cba 208 Pfam PF02570 Precorrin-8X methylmutase 10 204 4.4E-69 T 06-07-2017 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 BWK49_RS13520 b92039c2949b1d65d4c9c20b5be30cba 208 SUPERFAMILY SSF63965 2 205 8.37E-70 T 06-07-2017 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 BWK49_RS13520 b92039c2949b1d65d4c9c20b5be30cba 208 Gene3D G3DSA:3.40.50.10230 3 204 1.2E-76 T 06-07-2017 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 BWK49_RS05440 f4db60814ffca27dab571ba5263f7fed 143 Gene3D G3DSA:1.10.10.60 20 46 2.2E-4 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS05440 f4db60814ffca27dab571ba5263f7fed 143 Gene3D G3DSA:1.10.357.10 47 134 8.2E-4 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS05440 f4db60814ffca27dab571ba5263f7fed 143 ProDom PD020942 TRANSPOSASE C TN554 TRANSPOSON TRANSPOSITION FOR DNA-BINDING TRANSPOSABLE DNA ELEMENT 3 121 4.0E-26 T 06-07-2017 BWK49_RS18845 e4a84413b1cdc447de6b301d55d89ebd 184 Gene3D G3DSA:3.30.420.10 1 157 9.9E-55 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS18845 e4a84413b1cdc447de6b301d55d89ebd 184 TIGRFAM TIGR00228 ruvC: crossover junction endodeoxyribonuclease RuvC 3 155 4.8E-32 T 06-07-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 BWK49_RS18845 e4a84413b1cdc447de6b301d55d89ebd 184 Pfam PF02075 Crossover junction endodeoxyribonuclease RuvC 3 152 5.9E-63 T 06-07-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 BWK49_RS18845 e4a84413b1cdc447de6b301d55d89ebd 184 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 62 78 6.9E-40 T 06-07-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 BWK49_RS18845 e4a84413b1cdc447de6b301d55d89ebd 184 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 84 100 6.9E-40 T 06-07-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 BWK49_RS18845 e4a84413b1cdc447de6b301d55d89ebd 184 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 4 17 6.9E-40 T 06-07-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 BWK49_RS18845 e4a84413b1cdc447de6b301d55d89ebd 184 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 140 152 6.9E-40 T 06-07-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 BWK49_RS18845 e4a84413b1cdc447de6b301d55d89ebd 184 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 108 127 6.9E-40 T 06-07-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 BWK49_RS18845 e4a84413b1cdc447de6b301d55d89ebd 184 Hamap MF_00034 Crossover junction endodeoxyribonuclease RuvC [ruvC]. 1 155 44.597 T 06-07-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 BWK49_RS18845 e4a84413b1cdc447de6b301d55d89ebd 184 SUPERFAMILY SSF53098 1 158 6.45E-44 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS18845 e4a84413b1cdc447de6b301d55d89ebd 184 ProSitePatterns PS01321 Crossover junction endodeoxyribonuclease ruvC signature. 114 149 - T 06-07-2017 IPR020563 Crossover junction endodeoxyribonuclease RuvC, magnesium-binding site GO:0008821 BWK49_RS14920 5e47b776c852c530fc4d42bf9dcd1613 252 PIRSF PIRSF026622 7 252 7.2E-109 T 06-07-2017 IPR015837 Uncharacterised conserved protein UCP026622, CAAX protease-type BWK49_RS14920 5e47b776c852c530fc4d42bf9dcd1613 252 Pfam PF02517 CAAX protease self-immunity 126 238 1.2E-15 T 06-07-2017 IPR003675 CAAX amino terminal protease GO:0016020 BWK49_RS17160 c2fb6e33aee929a95a5c5ade8de72d08 404 Gene3D G3DSA:3.40.50.300 1 192 5.8E-66 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS17160 c2fb6e33aee929a95a5c5ade8de72d08 404 SUPERFAMILY SSF52540 1 193 6.61E-36 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS17160 c2fb6e33aee929a95a5c5ade8de72d08 404 Pfam PF01121 Dephospho-CoA kinase 4 178 6.8E-59 T 06-07-2017 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24 BWK49_RS17160 c2fb6e33aee929a95a5c5ade8de72d08 404 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 1 196 24.676 T 06-07-2017 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24 BWK49_RS17160 c2fb6e33aee929a95a5c5ade8de72d08 404 Pfam PF04229 GrpB protein 210 392 9.0E-44 T 06-07-2017 IPR007344 GrpB/Dephospho-CoA kinase BWK49_RS17160 c2fb6e33aee929a95a5c5ade8de72d08 404 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 4 185 8.8E-40 T 06-07-2017 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24 BWK49_RS17160 c2fb6e33aee929a95a5c5ade8de72d08 404 SUPERFAMILY SSF81301 213 398 2.52E-43 T 06-07-2017 BWK49_RS17160 c2fb6e33aee929a95a5c5ade8de72d08 404 Gene3D G3DSA:3.30.460.10 210 398 1.0E-54 T 06-07-2017 BWK49_RS08630 67eddf029a2f1dc1e2e08ee8ab0700aa 275 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS08630 67eddf029a2f1dc1e2e08ee8ab0700aa 275 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 7.8E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS08630 67eddf029a2f1dc1e2e08ee8ab0700aa 275 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 7.8E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS08630 67eddf029a2f1dc1e2e08ee8ab0700aa 275 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 7.8E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS08630 67eddf029a2f1dc1e2e08ee8ab0700aa 275 Gene3D G3DSA:3.40.50.720 5 238 2.8E-62 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS08630 67eddf029a2f1dc1e2e08ee8ab0700aa 275 SUPERFAMILY SSF51735 2 255 8.45E-63 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS08630 67eddf029a2f1dc1e2e08ee8ab0700aa 275 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 193 0.0018 T 06-07-2017 BWK49_RS08630 67eddf029a2f1dc1e2e08ee8ab0700aa 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 2.0E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS08630 67eddf029a2f1dc1e2e08ee8ab0700aa 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 2.0E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS08630 67eddf029a2f1dc1e2e08ee8ab0700aa 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 2.0E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS08630 67eddf029a2f1dc1e2e08ee8ab0700aa 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 2.0E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS08630 67eddf029a2f1dc1e2e08ee8ab0700aa 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 2.0E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS08630 67eddf029a2f1dc1e2e08ee8ab0700aa 275 Pfam PF00106 short chain dehydrogenase 7 201 1.1E-50 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS07640 bd2b8bc27b46736fc23e49f7d4063390 543 Pfam PF13193 AMP-binding enzyme C-terminal domain 446 521 3.0E-19 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS07640 bd2b8bc27b46736fc23e49f7d4063390 543 Gene3D G3DSA:2.30.38.10 357 431 2.7E-18 T 06-07-2017 BWK49_RS07640 bd2b8bc27b46736fc23e49f7d4063390 543 Gene3D G3DSA:3.30.300.30 432 531 8.0E-32 T 06-07-2017 BWK49_RS07640 bd2b8bc27b46736fc23e49f7d4063390 543 Gene3D G3DSA:3.40.50.980 47 188 1.1E-30 T 06-07-2017 BWK49_RS07640 bd2b8bc27b46736fc23e49f7d4063390 543 ProSitePatterns PS00455 Putative AMP-binding domain signature. 182 193 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS07640 bd2b8bc27b46736fc23e49f7d4063390 543 Pfam PF00501 AMP-binding enzyme 21 437 6.0E-99 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS07640 bd2b8bc27b46736fc23e49f7d4063390 543 Gene3D G3DSA:3.40.50.980 189 339 7.8E-37 T 06-07-2017 BWK49_RS07640 bd2b8bc27b46736fc23e49f7d4063390 543 SUPERFAMILY SSF56801 8 533 8.63E-142 T 06-07-2017 BWK49_RS21620 0b3d909aa205ff1c6c59a9130c9f2bcc 547 SUPERFAMILY SSF53738 25 233 4.0E-47 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 BWK49_RS21620 0b3d909aa205ff1c6c59a9130c9f2bcc 547 Gene3D G3DSA:3.40.120.10 312 448 1.4E-34 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 BWK49_RS21620 0b3d909aa205ff1c6c59a9130c9f2bcc 547 SUPERFAMILY SSF55957 435 547 8.37E-21 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 BWK49_RS21620 0b3d909aa205ff1c6c59a9130c9f2bcc 547 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 141 150 - T 06-07-2017 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 BWK49_RS21620 0b3d909aa205ff1c6c59a9130c9f2bcc 547 Gene3D G3DSA:3.40.120.10 224 311 5.2E-40 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 BWK49_RS21620 0b3d909aa205ff1c6c59a9130c9f2bcc 547 Gene3D G3DSA:3.30.310.50 469 546 7.7E-30 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 BWK49_RS21620 0b3d909aa205ff1c6c59a9130c9f2bcc 547 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 208 317 4.8E-9 T 06-07-2017 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 BWK49_RS21620 0b3d909aa205ff1c6c59a9130c9f2bcc 547 SUPERFAMILY SSF53738 308 450 3.24E-33 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 BWK49_RS21620 0b3d909aa205ff1c6c59a9130c9f2bcc 547 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 483 541 9.2E-9 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 BWK49_RS21620 0b3d909aa205ff1c6c59a9130c9f2bcc 547 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 323 443 4.5E-29 T 06-07-2017 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 BWK49_RS21620 0b3d909aa205ff1c6c59a9130c9f2bcc 547 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 40 181 5.5E-37 T 06-07-2017 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 BWK49_RS21620 0b3d909aa205ff1c6c59a9130c9f2bcc 547 TIGRFAM TIGR01132 pgm: phosphoglucomutase, alpha-D-glucose phosphate-specific 1 547 1.8E-302 T 06-07-2017 IPR005852 Phosphoglucomutase, alpha-D-glucose specific GO:0004614|GO:0005975 KEGG: 00010+5.4.2.2|KEGG: 00030+5.4.2.2|KEGG: 00052+5.4.2.2|KEGG: 00230+5.4.2.2|KEGG: 00500+5.4.2.2|KEGG: 00520+5.4.2.2|KEGG: 00521+5.4.2.2|MetaCyc: PWY-2723|MetaCyc: PWY-3801|MetaCyc: PWY-5384|MetaCyc: PWY-5661|MetaCyc: PWY-5940|MetaCyc: PWY-5941|MetaCyc: PWY-622|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|MetaCyc: PWY-7343 BWK49_RS21620 0b3d909aa205ff1c6c59a9130c9f2bcc 547 Gene3D G3DSA:3.40.120.10 28 223 5.8E-56 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 BWK49_RS28010 f87de781f00c1270de483bf3e8971f05 186 Gene3D G3DSA:2.30.110.10 18 156 3.7E-15 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 BWK49_RS28010 f87de781f00c1270de483bf3e8971f05 186 SUPERFAMILY SSF50475 14 153 6.92E-20 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 BWK49_RS28010 f87de781f00c1270de483bf3e8971f05 186 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 22 105 4.0E-5 T 06-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 BWK49_RS28885 f3bc09644e6fb72ad335126ea87ffb37 83 SUPERFAMILY SSF47598 5 44 5.23E-8 T 06-07-2017 IPR010985 Ribbon-helix-helix GO:0006355 BWK49_RS28885 f3bc09644e6fb72ad335126ea87ffb37 83 Pfam PF03693 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH 2 79 1.1E-38 T 06-07-2017 IPR022789 Antitoxin ParD BWK49_RS28885 f3bc09644e6fb72ad335126ea87ffb37 83 TIGRFAM TIGR02606 antidote_CC2985: putative addiction module antidote protein, CC2985 family 4 72 1.5E-26 T 06-07-2017 IPR022789 Antitoxin ParD BWK49_RS23800 ba73d1bf427919b1a49dadb89f2e5d8e 263 Pfam PF09990 Predicted membrane protein (DUF2231) 57 148 5.2E-7 T 06-07-2017 IPR019251 Domain of unknown function DUF2231, transmembrane BWK49_RS23800 ba73d1bf427919b1a49dadb89f2e5d8e 263 Gene3D G3DSA:2.102.10.10 159 259 4.6E-31 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS23800 ba73d1bf427919b1a49dadb89f2e5d8e 263 Pfam PF00355 Rieske [2Fe-2S] domain 163 248 3.8E-18 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS23800 ba73d1bf427919b1a49dadb89f2e5d8e 263 SUPERFAMILY SSF50022 127 258 2.23E-29 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS00545 304987fa252c30808689ba1afbbebdc9 477 SUPERFAMILY SSF56176 45 240 4.11E-49 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 BWK49_RS00545 304987fa252c30808689ba1afbbebdc9 477 Gene3D G3DSA:3.30.43.10 67 124 3.0E-12 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 BWK49_RS00545 304987fa252c30808689ba1afbbebdc9 477 Pfam PF08031 Berberine and berberine like 437 469 4.0E-6 T 06-07-2017 IPR012951 Berberine/berberine-like GO:0016491|GO:0050660|GO:0055114 BWK49_RS00545 304987fa252c30808689ba1afbbebdc9 477 Gene3D G3DSA:3.30.465.10 131 240 1.7E-9 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 BWK49_RS00545 304987fa252c30808689ba1afbbebdc9 477 ProSitePatterns PS00862 Oxygen oxidoreductases covalent FAD-binding site. 73 106 - T 06-07-2017 IPR006093 Oxygen oxidoreductase covalent FAD-binding site GO:0016491|GO:0055114 BWK49_RS00545 304987fa252c30808689ba1afbbebdc9 477 Pfam PF01565 FAD binding domain 73 208 3.9E-30 T 06-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 BWK49_RS26010 21c9132437c39fd76da08a0da98a8d64 293 SUPERFAMILY SSF53254 23 258 2.04E-26 T 06-07-2017 IPR029033 Histidine phosphatase superfamily BWK49_RS26010 21c9132437c39fd76da08a0da98a8d64 293 SMART SM00855 22 177 1.3E-8 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 BWK49_RS26010 21c9132437c39fd76da08a0da98a8d64 293 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 25 118 8.3E-22 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 BWK49_RS26010 21c9132437c39fd76da08a0da98a8d64 293 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 25 34 - T 06-07-2017 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 BWK49_RS26010 21c9132437c39fd76da08a0da98a8d64 293 Gene3D G3DSA:3.40.50.1240 24 114 1.2E-22 T 06-07-2017 IPR029033 Histidine phosphatase superfamily BWK49_RS27945 42d75b6c467eaa13db599b4da9d1e931 462 Pfam PF03972 MmgE/PrpD family 2 434 2.0E-101 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 BWK49_RS27945 42d75b6c467eaa13db599b4da9d1e931 462 Gene3D G3DSA:3.30.1330.120 257 402 1.5E-22 T 06-07-2017 BWK49_RS27945 42d75b6c467eaa13db599b4da9d1e931 462 SUPERFAMILY SSF103378 2 442 1.44E-88 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 BWK49_RS23725 e599a1220b45b6f63cf4422eb33ac646 530 SUPERFAMILY SSF52317 15 235 5.18E-51 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like BWK49_RS23725 e599a1220b45b6f63cf4422eb33ac646 530 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 211 530 1.6E-143 T 06-07-2017 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 BWK49_RS23725 e599a1220b45b6f63cf4422eb33ac646 530 SUPERFAMILY SSF54810 409 530 1.44E-45 T 06-07-2017 BWK49_RS23725 e599a1220b45b6f63cf4422eb33ac646 530 Gene3D G3DSA:3.30.300.10 405 530 5.3E-49 T 06-07-2017 BWK49_RS23725 e599a1220b45b6f63cf4422eb33ac646 530 SUPERFAMILY SSF52402 191 450 1.53E-52 T 06-07-2017 BWK49_RS23725 e599a1220b45b6f63cf4422eb33ac646 530 Pfam PF00117 Glutamine amidotransferase class-I 19 197 2.9E-38 T 06-07-2017 IPR017926 Glutamine amidotransferase BWK49_RS23725 e599a1220b45b6f63cf4422eb33ac646 530 PRINTS PR00097 Anthranilate synthase component II signature 175 188 2.2E-6 T 06-07-2017 BWK49_RS23725 e599a1220b45b6f63cf4422eb33ac646 530 PRINTS PR00097 Anthranilate synthase component II signature 88 99 2.2E-6 T 06-07-2017 BWK49_RS23725 e599a1220b45b6f63cf4422eb33ac646 530 PRINTS PR00097 Anthranilate synthase component II signature 61 70 2.2E-6 T 06-07-2017 BWK49_RS23725 e599a1220b45b6f63cf4422eb33ac646 530 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 14 530 52.558 T 06-07-2017 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 BWK49_RS23725 e599a1220b45b6f63cf4422eb33ac646 530 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 17 201 2.6E-72 T 06-07-2017 IPR004739 GMP synthase, N-terminal GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 BWK49_RS23725 e599a1220b45b6f63cf4422eb33ac646 530 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 88 104 9.7E-6 T 06-07-2017 BWK49_RS23725 e599a1220b45b6f63cf4422eb33ac646 530 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 58 72 9.7E-6 T 06-07-2017 BWK49_RS23725 e599a1220b45b6f63cf4422eb33ac646 530 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 17 31 9.7E-6 T 06-07-2017 BWK49_RS23725 e599a1220b45b6f63cf4422eb33ac646 530 Gene3D G3DSA:3.40.50.880 16 199 1.2E-56 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like BWK49_RS23725 e599a1220b45b6f63cf4422eb33ac646 530 Pfam PF00958 GMP synthase C terminal domain 437 529 1.7E-38 T 06-07-2017 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 BWK49_RS23725 e599a1220b45b6f63cf4422eb33ac646 530 Pfam PF02540 NAD synthase 216 284 8.8E-6 T 06-07-2017 IPR022310 NAD/GMP synthase BWK49_RS23725 e599a1220b45b6f63cf4422eb33ac646 530 PRINTS PR00096 Glutamine amidotransferase superfamily signature 88 99 2.0E-8 T 06-07-2017 BWK49_RS23725 e599a1220b45b6f63cf4422eb33ac646 530 PRINTS PR00096 Glutamine amidotransferase superfamily signature 175 188 2.0E-8 T 06-07-2017 BWK49_RS23725 e599a1220b45b6f63cf4422eb33ac646 530 PRINTS PR00096 Glutamine amidotransferase superfamily signature 61 70 2.0E-8 T 06-07-2017 BWK49_RS23725 e599a1220b45b6f63cf4422eb33ac646 530 Gene3D G3DSA:3.40.50.620 206 403 2.9E-53 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold BWK49_RS00705 cbec526e85eb79308a6c1aa5209b0680 323 Gene3D G3DSA:3.40.50.720 9 118 2.0E-29 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS00705 cbec526e85eb79308a6c1aa5209b0680 323 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 42 316 9.1E-23 T 06-07-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 BWK49_RS00705 cbec526e85eb79308a6c1aa5209b0680 323 SUPERFAMILY SSF51735 104 286 2.41E-48 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS00705 cbec526e85eb79308a6c1aa5209b0680 323 Gene3D G3DSA:3.40.50.720 119 288 3.0E-50 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS00705 cbec526e85eb79308a6c1aa5209b0680 323 SUPERFAMILY SSF52283 9 140 7.94E-31 T 06-07-2017 BWK49_RS00705 cbec526e85eb79308a6c1aa5209b0680 323 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 112 285 1.4E-45 T 06-07-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 BWK49_RS09200 b89942a6b2c249daec553891d488361d 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 2.1E-50 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS09200 b89942a6b2c249daec553891d488361d 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 2.1E-50 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS09200 b89942a6b2c249daec553891d488361d 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 2.1E-50 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS09200 b89942a6b2c249daec553891d488361d 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 2.1E-50 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS09200 b89942a6b2c249daec553891d488361d 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 2.1E-50 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS09200 b89942a6b2c249daec553891d488361d 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 2.1E-50 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS09200 b89942a6b2c249daec553891d488361d 249 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS09200 b89942a6b2c249daec553891d488361d 249 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 10 193 1.9E-5 T 06-07-2017 BWK49_RS09200 b89942a6b2c249daec553891d488361d 249 SUPERFAMILY SSF51735 9 249 1.97E-82 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS09200 b89942a6b2c249daec553891d488361d 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 4.2E-15 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS09200 b89942a6b2c249daec553891d488361d 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 4.2E-15 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS09200 b89942a6b2c249daec553891d488361d 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 4.2E-15 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS09200 b89942a6b2c249daec553891d488361d 249 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 248 3.9E-67 T 06-07-2017 BWK49_RS09200 b89942a6b2c249daec553891d488361d 249 Gene3D G3DSA:3.40.50.720 7 248 2.7E-87 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS07530 f067b9fe12182b08b90bcece822142d0 316 Gene3D G3DSA:3.30.420.150 133 315 1.2E-58 T 06-07-2017 BWK49_RS07530 f067b9fe12182b08b90bcece822142d0 316 Gene3D G3DSA:3.30.420.40 4 131 1.7E-44 T 06-07-2017 BWK49_RS07530 f067b9fe12182b08b90bcece822142d0 316 SUPERFAMILY SSF53067 5 131 2.3E-29 T 06-07-2017 BWK49_RS07530 f067b9fe12182b08b90bcece822142d0 316 Pfam PF02541 Ppx/GppA phosphatase family 23 312 8.0E-81 T 06-07-2017 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 BWK49_RS07530 f067b9fe12182b08b90bcece822142d0 316 SUPERFAMILY SSF53067 137 314 3.14E-36 T 06-07-2017 BWK49_RS08970 5b75d787bb5a7a4deaba0bc8e27db382 486 Gene3D G3DSA:1.10.1140.10 367 482 6.3E-47 T 06-07-2017 IPR024034 ATPase, F1 complex beta subunit/V1 complex, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 BWK49_RS08970 5b75d787bb5a7a4deaba0bc8e27db382 486 Gene3D G3DSA:3.40.50.300 97 364 1.9E-100 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS08970 5b75d787bb5a7a4deaba0bc8e27db382 486 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 20 482 4.7E-247 T 06-07-2017 IPR005722 ATPase, F1 complex, beta subunit GO:0015986|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201 BWK49_RS08970 5b75d787bb5a7a4deaba0bc8e27db382 486 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 151 364 3.6E-62 T 06-07-2017 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 BWK49_RS08970 5b75d787bb5a7a4deaba0bc8e27db382 486 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 355 364 - T 06-07-2017 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 BWK49_RS08970 5b75d787bb5a7a4deaba0bc8e27db382 486 SMART SM00382 163 348 1.2E-6 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS08970 5b75d787bb5a7a4deaba0bc8e27db382 486 SUPERFAMILY SSF50615 20 95 1.36E-23 T 06-07-2017 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 BWK49_RS08970 5b75d787bb5a7a4deaba0bc8e27db382 486 Hamap MF_01347 ATP synthase subunit beta [atpB]. 18 482 54.29 T 06-07-2017 IPR005722 ATPase, F1 complex, beta subunit GO:0015986|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201 BWK49_RS08970 5b75d787bb5a7a4deaba0bc8e27db382 486 Gene3D G3DSA:2.40.10.170 11 95 3.9E-29 T 06-07-2017 BWK49_RS08970 5b75d787bb5a7a4deaba0bc8e27db382 486 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 23 94 1.7E-21 T 06-07-2017 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 BWK49_RS08970 5b75d787bb5a7a4deaba0bc8e27db382 486 SUPERFAMILY SSF52540 98 369 1.38E-84 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS08970 5b75d787bb5a7a4deaba0bc8e27db382 486 SUPERFAMILY SSF47917 367 482 2.54E-47 T 06-07-2017 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 BWK49_RS22120 e99e476dccf9cf74cb0f1563910cc3f8 363 Gene3D G3DSA:1.10.10.60 309 355 6.6E-7 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS22120 e99e476dccf9cf74cb0f1563910cc3f8 363 SUPERFAMILY SSF46689 308 359 2.93E-6 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS22120 e99e476dccf9cf74cb0f1563910cc3f8 363 Pfam PF12833 Helix-turn-helix domain 277 359 2.2E-22 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 BWK49_RS22120 e99e476dccf9cf74cb0f1563910cc3f8 363 Gene3D G3DSA:1.10.10.60 254 308 6.1E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS22120 e99e476dccf9cf74cb0f1563910cc3f8 363 SUPERFAMILY SSF46689 256 305 7.56E-8 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS22120 e99e476dccf9cf74cb0f1563910cc3f8 363 SMART SM00342 271 357 1.6E-23 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 BWK49_RS22120 e99e476dccf9cf74cb0f1563910cc3f8 363 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 308 353 - T 06-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 BWK49_RS04985 43b24397b545da23820548258189453d 542 SUPERFAMILY SSF51905 38 258 3.46E-51 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS04985 43b24397b545da23820548258189453d 542 SUPERFAMILY SSF51905 329 449 3.46E-51 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS04985 43b24397b545da23820548258189453d 542 Gene3D G3DSA:3.50.50.60 353 521 4.4E-7 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS04985 43b24397b545da23820548258189453d 542 Gene3D G3DSA:3.50.50.60 31 239 2.4E-57 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS04985 43b24397b545da23820548258189453d 542 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 204 229 1.2E-6 T 06-07-2017 BWK49_RS04985 43b24397b545da23820548258189453d 542 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 163 172 1.2E-6 T 06-07-2017 BWK49_RS04985 43b24397b545da23820548258189453d 542 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 60 1.2E-6 T 06-07-2017 BWK49_RS04985 43b24397b545da23820548258189453d 542 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 37 247 6.2E-14 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS07025 15bfdc6f25f6c5bb0712423283088246 678 SMART SM00327 486 672 3.2E-11 T 06-07-2017 IPR002035 von Willebrand factor, type A BWK49_RS07025 15bfdc6f25f6c5bb0712423283088246 678 Gene3D G3DSA:3.40.50.410 487 589 1.7E-5 T 06-07-2017 IPR002035 von Willebrand factor, type A BWK49_RS07025 15bfdc6f25f6c5bb0712423283088246 678 SUPERFAMILY SSF53300 487 661 1.11E-14 T 06-07-2017 IPR002035 von Willebrand factor, type A BWK49_RS04550 c0f5ef0d67808612a74b623674154bf7 733 Gene3D G3DSA:1.10.443.10 384 543 1.9E-6 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 BWK49_RS04550 c0f5ef0d67808612a74b623674154bf7 733 SUPERFAMILY SSF56349 384 543 2.83E-6 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 BWK49_RS06610 2430d1698f66928d1efed5ecb43fb35c 650 SUPERFAMILY SSF56645 56 289 1.27E-58 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS06610 2430d1698f66928d1efed5ecb43fb35c 650 Gene3D G3DSA:1.20.140.10 266 438 5.4E-51 T 06-07-2017 BWK49_RS06610 2430d1698f66928d1efed5ecb43fb35c 650 Gene3D G3DSA:2.40.110.10 166 265 5.2E-31 T 06-07-2017 BWK49_RS06610 2430d1698f66928d1efed5ecb43fb35c 650 Gene3D G3DSA:1.10.540.10 28 165 4.1E-30 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS06610 2430d1698f66928d1efed5ecb43fb35c 650 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 277 435 1.1E-33 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS06610 2430d1698f66928d1efed5ecb43fb35c 650 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 57 163 1.8E-21 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS06610 2430d1698f66928d1efed5ecb43fb35c 650 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 167 264 5.1E-20 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 BWK49_RS06610 2430d1698f66928d1efed5ecb43fb35c 650 SUPERFAMILY SSF47203 277 436 1.06E-38 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS06630 7d661179742813460cb379aff785353d 556 Pfam PF07690 Major Facilitator Superfamily 120 489 2.5E-12 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 BWK49_RS06630 7d661179742813460cb379aff785353d 556 SUPERFAMILY SSF103473 113 519 3.49E-17 T 06-07-2017 IPR020846 Major facilitator superfamily domain BWK49_RS21965 2b67950ae81319aeda61577c0266fd04 412 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 14 145 4.7E-11 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS21965 2b67950ae81319aeda61577c0266fd04 412 Gene3D G3DSA:2.40.110.10 149 245 2.5E-34 T 06-07-2017 BWK49_RS21965 2b67950ae81319aeda61577c0266fd04 412 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 256 406 7.5E-44 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS21965 2b67950ae81319aeda61577c0266fd04 412 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 149 244 6.9E-21 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 BWK49_RS21965 2b67950ae81319aeda61577c0266fd04 412 Gene3D G3DSA:1.10.540.10 4 145 3.6E-24 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS21965 2b67950ae81319aeda61577c0266fd04 412 SUPERFAMILY SSF47203 254 409 1.61E-41 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS21965 2b67950ae81319aeda61577c0266fd04 412 Gene3D G3DSA:1.20.140.10 246 408 2.4E-48 T 06-07-2017 BWK49_RS21965 2b67950ae81319aeda61577c0266fd04 412 SUPERFAMILY SSF56645 28 267 8.64E-62 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS19950 41d1a5ed620b9b076a0a57b97cf9e918 535 SUPERFAMILY SSF103473 292 514 3.01E-57 T 06-07-2017 IPR020846 Major facilitator superfamily domain BWK49_RS19950 41d1a5ed620b9b076a0a57b97cf9e918 535 SUPERFAMILY SSF103473 44 244 3.01E-57 T 06-07-2017 IPR020846 Major facilitator superfamily domain BWK49_RS19950 41d1a5ed620b9b076a0a57b97cf9e918 535 Pfam PF07690 Major Facilitator Superfamily 66 454 2.2E-42 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 BWK49_RS19950 41d1a5ed620b9b076a0a57b97cf9e918 535 Gene3D G3DSA:1.20.1250.20 307 521 3.8E-10 T 06-07-2017 BWK49_RS19950 41d1a5ed620b9b076a0a57b97cf9e918 535 Gene3D G3DSA:1.20.1250.20 59 244 1.1E-27 T 06-07-2017 BWK49_RS27340 c395034f75d2f2f3b2d9a162c2a5892f 234 SUPERFAMILY SSF54909 19 89 7.72E-7 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel BWK49_RS27340 c395034f75d2f2f3b2d9a162c2a5892f 234 Pfam PF07978 NIPSNAP 19 82 5.9E-5 T 06-07-2017 IPR012577 NIPSNAP BWK49_RS06150 14d2eebc3550c29da3a8b9599b6ebdca 271 Gene3D G3DSA:1.10.1040.10 164 252 2.0E-17 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 BWK49_RS06150 14d2eebc3550c29da3a8b9599b6ebdca 271 SUPERFAMILY SSF51735 1 162 2.9E-40 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS06150 14d2eebc3550c29da3a8b9599b6ebdca 271 Gene3D G3DSA:3.40.50.720 1 162 1.0E-46 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS06150 14d2eebc3550c29da3a8b9599b6ebdca 271 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 164 260 4.7E-17 T 06-07-2017 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 BWK49_RS06150 14d2eebc3550c29da3a8b9599b6ebdca 271 PIRSF PIRSF000103 1 270 3.2E-61 T 06-07-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 BWK49_RS06150 14d2eebc3550c29da3a8b9599b6ebdca 271 SUPERFAMILY SSF48179 162 262 3.66E-17 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 BWK49_RS06150 14d2eebc3550c29da3a8b9599b6ebdca 271 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 161 5.9E-39 T 06-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 BWK49_RS06150 14d2eebc3550c29da3a8b9599b6ebdca 271 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 5 18 - T 06-07-2017 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 BWK49_RS03995 83b532f0ec0f6f73b91fddedf4c9e06e 461 Pfam PF16925 Bacterial transcriptional repressor C-terminal 331 433 7.3E-7 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS03995 83b532f0ec0f6f73b91fddedf4c9e06e 461 SUPERFAMILY SSF46689 12 86 3.08E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS03995 83b532f0ec0f6f73b91fddedf4c9e06e 461 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 69 7.2E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS03995 83b532f0ec0f6f73b91fddedf4c9e06e 461 Pfam PF00440 Bacterial regulatory proteins, tetR family 260 304 3.1E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS03995 83b532f0ec0f6f73b91fddedf4c9e06e 461 Gene3D G3DSA:1.10.10.60 252 303 7.4E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS03995 83b532f0ec0f6f73b91fddedf4c9e06e 461 SUPERFAMILY SSF46689 247 328 3.69E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS03995 83b532f0ec0f6f73b91fddedf4c9e06e 461 SUPERFAMILY SSF48498 93 203 9.2E-15 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS03995 83b532f0ec0f6f73b91fddedf4c9e06e 461 Gene3D G3DSA:1.10.357.10 304 441 6.1E-25 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS03995 83b532f0ec0f6f73b91fddedf4c9e06e 461 Gene3D G3DSA:1.10.357.10 14 203 3.4E-28 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS03995 83b532f0ec0f6f73b91fddedf4c9e06e 461 SUPERFAMILY SSF48498 327 442 2.34E-22 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS08300 1b07fcf790d67279228a295473675e8e 254 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 13 137 6.8E-9 T 06-07-2017 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 BWK49_RS08300 1b07fcf790d67279228a295473675e8e 254 SUPERFAMILY SSF109854 12 137 1.56E-9 T 06-07-2017 BWK49_RS06960 cfe674082f46d383c6b9148340e4bb00 780 Gene3D G3DSA:1.10.10.160 126 206 7.5E-24 T 06-07-2017 IPR013986 DExx box DNA helicase domain BWK49_RS06960 cfe674082f46d383c6b9148340e4bb00 780 Gene3D G3DSA:3.40.50.300 207 314 4.9E-69 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS06960 cfe674082f46d383c6b9148340e4bb00 780 Gene3D G3DSA:3.40.50.300 15 121 4.9E-69 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS06960 cfe674082f46d383c6b9148340e4bb00 780 Pfam PF00580 UvrD/REP helicase N-terminal domain 21 300 2.6E-73 T 06-07-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 BWK49_RS06960 cfe674082f46d383c6b9148340e4bb00 780 Pfam PF13361 UvrD-like helicase C-terminal domain 306 661 2.5E-68 T 06-07-2017 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 BWK49_RS06960 cfe674082f46d383c6b9148340e4bb00 780 TIGRFAM TIGR01073 pcrA: ATP-dependent DNA helicase PcrA 17 777 1.9E-277 T 06-07-2017 IPR005751 ATP-dependent DNA helicase PcrA GO:0004003|GO:0005737|GO:0006268 BWK49_RS06960 cfe674082f46d383c6b9148340e4bb00 780 Gene3D G3DSA:3.40.50.300 600 691 2.3E-68 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS06960 cfe674082f46d383c6b9148340e4bb00 780 Gene3D G3DSA:3.40.50.300 315 417 2.3E-68 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS06960 cfe674082f46d383c6b9148340e4bb00 780 Gene3D G3DSA:1.10.486.10 418 584 2.3E-47 T 06-07-2017 BWK49_RS06960 cfe674082f46d383c6b9148340e4bb00 780 SUPERFAMILY SSF52540 15 690 3.2E-172 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS14720 49dde37c984b66604cd1e570acf82b1c 186 SUPERFAMILY SSF101874 7 184 3.66E-23 T 06-07-2017 IPR007372 Lipid/polyisoprenoid-binding, YceI-like BWK49_RS14720 49dde37c984b66604cd1e570acf82b1c 186 SMART SM00867 8 183 4.7E-19 T 06-07-2017 IPR007372 Lipid/polyisoprenoid-binding, YceI-like BWK49_RS14720 49dde37c984b66604cd1e570acf82b1c 186 Pfam PF04264 YceI-like domain 23 180 5.1E-14 T 06-07-2017 IPR007372 Lipid/polyisoprenoid-binding, YceI-like BWK49_RS14720 49dde37c984b66604cd1e570acf82b1c 186 Gene3D G3DSA:2.40.128.110 8 184 5.9E-26 T 06-07-2017 IPR007372 Lipid/polyisoprenoid-binding, YceI-like BWK49_RS09670 0780d221c30696502a7e94fdb951210b 788 SUPERFAMILY SSF82866 134 339 7.19E-26 T 06-07-2017 BWK49_RS09670 0780d221c30696502a7e94fdb951210b 788 Gene3D G3DSA:1.20.1640.10 524 741 2.4E-30 T 06-07-2017 BWK49_RS09670 0780d221c30696502a7e94fdb951210b 788 Gene3D G3DSA:1.20.1640.10 150 341 2.9E-26 T 06-07-2017 BWK49_RS09670 0780d221c30696502a7e94fdb951210b 788 SUPERFAMILY SSF82866 510 737 2.88E-25 T 06-07-2017 BWK49_RS09670 0780d221c30696502a7e94fdb951210b 788 Pfam PF03176 MMPL family 44 381 1.1E-48 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 BWK49_RS09670 0780d221c30696502a7e94fdb951210b 788 Pfam PF03176 MMPL family 415 740 2.8E-29 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 BWK49_RS09940 00dd599aa012dc807cfa0d2776539f60 651 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 37 225 4.7E-26 T 06-07-2017 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 BWK49_RS09940 00dd599aa012dc807cfa0d2776539f60 651 Gene3D G3DSA:3.40.920.10 29 229 1.3E-24 T 06-07-2017 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 BWK49_RS09940 00dd599aa012dc807cfa0d2776539f60 651 TIGRFAM TIGR03710 OAFO_sf: 2-oxoacid:acceptor oxidoreductase, alpha subunit 28 618 1.4E-200 T 06-07-2017 IPR022367 2-oxoacid:acceptor oxidoreductase, alpha subunit KEGG: 00020+1.2.7.3|KEGG: 00720+1.2.7.3|MetaCyc: PWY-5392|MetaCyc: PWY-6969 BWK49_RS09940 00dd599aa012dc807cfa0d2776539f60 651 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 526 621 1.6E-8 T 06-07-2017 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II BWK49_RS09940 00dd599aa012dc807cfa0d2776539f60 651 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 277 486 7.6E-59 T 06-07-2017 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 BWK49_RS09940 00dd599aa012dc807cfa0d2776539f60 651 SUPERFAMILY SSF53323 31 248 6.54E-17 T 06-07-2017 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 BWK49_RS09940 00dd599aa012dc807cfa0d2776539f60 651 SUPERFAMILY SSF52518 249 509 2.99E-60 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS09940 00dd599aa012dc807cfa0d2776539f60 651 SUPERFAMILY SSF52922 524 627 4.0E-16 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 BWK49_RS09940 00dd599aa012dc807cfa0d2776539f60 651 Gene3D G3DSA:3.40.50.970 243 442 3.6E-73 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS09940 00dd599aa012dc807cfa0d2776539f60 651 Gene3D G3DSA:3.40.50.920 525 622 3.7E-11 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 BWK49_RS14645 8fb52e81f0b65fe93905e1fd2dd70e1a 355 Pfam PF04909 Amidohydrolase 4 354 1.2E-35 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 BWK49_RS14645 8fb52e81f0b65fe93905e1fd2dd70e1a 355 Gene3D G3DSA:3.20.20.140 3 355 2.4E-70 T 06-07-2017 BWK49_RS14645 8fb52e81f0b65fe93905e1fd2dd70e1a 355 SUPERFAMILY SSF51556 62 354 8.9E-71 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS14645 8fb52e81f0b65fe93905e1fd2dd70e1a 355 SUPERFAMILY SSF51556 1 30 8.9E-71 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS01215 b673df09c7aae077184e2333b454b297 207 Gene3D G3DSA:1.20.120.450 4 54 4.5E-8 T 06-07-2017 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase BWK49_RS01215 b673df09c7aae077184e2333b454b297 207 SUPERFAMILY SSF109854 3 125 5.49E-18 T 06-07-2017 BWK49_RS01215 b673df09c7aae077184e2333b454b297 207 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 8 186 6.1E-38 T 06-07-2017 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type BWK49_RS01215 b673df09c7aae077184e2333b454b297 207 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 10 91 1.3E-10 T 06-07-2017 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 BWK49_RS10775 2e377f4ebf49787dd595486c1468df0d 490 Gene3D G3DSA:3.40.309.10 283 450 9.7E-59 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 BWK49_RS10775 2e377f4ebf49787dd595486c1468df0d 490 SUPERFAMILY SSF53720 4 487 4.32E-139 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 BWK49_RS10775 2e377f4ebf49787dd595486c1468df0d 490 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 259 266 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 BWK49_RS10775 2e377f4ebf49787dd595486c1468df0d 490 Pfam PF00171 Aldehyde dehydrogenase family 16 485 3.7E-142 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 BWK49_RS10775 2e377f4ebf49787dd595486c1468df0d 490 Gene3D G3DSA:3.40.605.10 5 282 3.4E-73 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 BWK49_RS15895 46c7948a6cae2680752d4d8424520916 306 SUPERFAMILY SSF51679 15 301 8.77E-58 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS15895 46c7948a6cae2680752d4d8424520916 306 Pfam PF00296 Luciferase-like monooxygenase 25 233 2.9E-44 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS15895 46c7948a6cae2680752d4d8424520916 306 TIGRFAM TIGR03619 F420_Rv2161c: probable F420-dependent oxidoreductase, Rv2161c family 32 279 3.9E-61 T 06-07-2017 IPR019921 Luciferase-like, F420-dependent oxidoreductase, Rv2161c, predicted BWK49_RS15895 46c7948a6cae2680752d4d8424520916 306 Gene3D G3DSA:3.20.20.30 17 305 7.4E-60 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS03780 f57276b3ab3cea6ce80dea6372664785 179 Gene3D G3DSA:3.10.450.50 5 137 4.5E-4 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS03780 f57276b3ab3cea6ce80dea6372664785 179 SUPERFAMILY SSF54427 5 132 2.93E-16 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS03775 dda361c8f1e32c5b1f62f44f4ae12ac8 375 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 61 75 - T 06-07-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 BWK49_RS03775 dda361c8f1e32c5b1f62f44f4ae12ac8 375 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 155 5.4E-28 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 BWK49_RS03775 dda361c8f1e32c5b1f62f44f4ae12ac8 375 Gene3D G3DSA:3.40.50.720 192 313 3.1E-21 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS03775 dda361c8f1e32c5b1f62f44f4ae12ac8 375 SMART SM00829 15 368 2.8E-5 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 BWK49_RS03775 dda361c8f1e32c5b1f62f44f4ae12ac8 375 Gene3D G3DSA:3.90.180.10 2 191 3.7E-61 T 06-07-2017 IPR011032 GroES-like BWK49_RS03775 dda361c8f1e32c5b1f62f44f4ae12ac8 375 SUPERFAMILY SSF50129 2 181 1.67E-59 T 06-07-2017 IPR011032 GroES-like BWK49_RS03775 dda361c8f1e32c5b1f62f44f4ae12ac8 375 Pfam PF00107 Zinc-binding dehydrogenase 197 328 1.1E-20 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 BWK49_RS03775 dda361c8f1e32c5b1f62f44f4ae12ac8 375 SUPERFAMILY SSF51735 158 337 5.18E-30 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS03775 dda361c8f1e32c5b1f62f44f4ae12ac8 375 TIGRFAM TIGR03989 Rxyl_3153: NDMA-dependent alcohol dehydrogenase, Rxyl_3153 family 2 370 2.4E-175 T 06-07-2017 IPR023921 Alcohol dehydrogenase, zinc-type, actinomycetes KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396 BWK49_RS03775 dda361c8f1e32c5b1f62f44f4ae12ac8 375 SUPERFAMILY SSF50129 322 370 1.46E-10 T 06-07-2017 IPR011032 GroES-like BWK49_RS19660 0d3f6060f1772daa162644227667ccb9 558 SMART SM00849 28 222 6.0E-22 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS19660 0d3f6060f1772daa162644227667ccb9 558 Hamap MF_01491 Ribonuclease J [rnj]. 11 558 39.665 T 06-07-2017 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 BWK49_RS19660 0d3f6060f1772daa162644227667ccb9 558 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 17 555 6.2E-134 T 06-07-2017 IPR004613 Ribonuclease J GO:0003723|GO:0046872 BWK49_RS19660 0d3f6060f1772daa162644227667ccb9 558 Pfam PF12706 Beta-lactamase superfamily domain 56 172 7.2E-13 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS19660 0d3f6060f1772daa162644227667ccb9 558 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 368 410 2.3E-9 T 06-07-2017 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain BWK49_RS19660 0d3f6060f1772daa162644227667ccb9 558 Gene3D G3DSA:3.60.15.10 16 262 1.8E-71 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS19660 0d3f6060f1772daa162644227667ccb9 558 PIRSF PIRSF004803 11 558 3.5E-184 T 06-07-2017 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 BWK49_RS19660 0d3f6060f1772daa162644227667ccb9 558 SUPERFAMILY SSF56281 16 431 2.1E-90 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS25340 e59ac108b90f3a78b7d9b9a011f9ba97 280 Gene3D G3DSA:3.20.20.150 3 278 5.8E-41 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain BWK49_RS25340 e59ac108b90f3a78b7d9b9a011f9ba97 280 Pfam PF01261 Xylose isomerase-like TIM barrel 23 229 1.1E-13 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain BWK49_RS25340 e59ac108b90f3a78b7d9b9a011f9ba97 280 SUPERFAMILY SSF51658 4 276 3.67E-40 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain BWK49_RS20185 ffeabab5b549fe318ea5d87703cf149b 144 Gene3D G3DSA:1.10.10.10 3 138 1.1E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS20185 ffeabab5b549fe318ea5d87703cf149b 144 Pfam PF01047 MarR family 37 92 6.2E-11 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 BWK49_RS20185 ffeabab5b549fe318ea5d87703cf149b 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 118 138 1.3E-5 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 BWK49_RS20185 ffeabab5b549fe318ea5d87703cf149b 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 52 68 1.3E-5 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 BWK49_RS20185 ffeabab5b549fe318ea5d87703cf149b 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 69 84 1.3E-5 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 BWK49_RS20185 ffeabab5b549fe318ea5d87703cf149b 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 88 104 1.3E-5 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 BWK49_RS20185 ffeabab5b549fe318ea5d87703cf149b 144 ProSitePatterns PS01117 MarR-type HTH domain signature. 66 101 - T 06-07-2017 IPR023187 Transcriptional regulator MarR-type, conserved site BWK49_RS20185 ffeabab5b549fe318ea5d87703cf149b 144 SUPERFAMILY SSF46785 3 139 1.07E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS20185 ffeabab5b549fe318ea5d87703cf149b 144 SMART SM00347 28 128 1.1E-21 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 BWK49_RS22845 f8683b1721c795600d646ec319c6734c 391 ProSitePatterns PS00737 Thiolases signature 2. 336 352 - T 06-07-2017 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 BWK49_RS22845 f8683b1721c795600d646ec319c6734c 391 SUPERFAMILY SSF53901 4 267 9.52E-66 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS22845 f8683b1721c795600d646ec319c6734c 391 Pfam PF00108 Thiolase, N-terminal domain 6 259 9.0E-59 T 06-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 BWK49_RS22845 f8683b1721c795600d646ec319c6734c 391 Pfam PF02803 Thiolase, C-terminal domain 268 389 9.7E-46 T 06-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 BWK49_RS22845 f8683b1721c795600d646ec319c6734c 391 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 7 388 4.4E-134 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 BWK49_RS22845 f8683b1721c795600d646ec319c6734c 391 Gene3D G3DSA:3.40.47.10 190 273 4.7E-60 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS22845 f8683b1721c795600d646ec319c6734c 391 Gene3D G3DSA:3.40.47.10 4 127 4.7E-60 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS22845 f8683b1721c795600d646ec319c6734c 391 SUPERFAMILY SSF53901 268 389 4.92E-43 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS22845 f8683b1721c795600d646ec319c6734c 391 Gene3D G3DSA:3.40.47.10 274 389 2.4E-56 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS22845 f8683b1721c795600d646ec319c6734c 391 Gene3D G3DSA:3.40.47.10 152 189 2.4E-56 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS22845 f8683b1721c795600d646ec319c6734c 391 PIRSF PIRSF000429 1 391 2.2E-118 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 BWK49_RS15255 bf2328900671eed4554aa59daf62d212 403 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 318 399 3.1E-17 T 06-07-2017 IPR022171 PPE family, C-terminal BWK49_RS15255 bf2328900671eed4554aa59daf62d212 403 Pfam PF00823 PPE family 6 162 1.6E-58 T 06-07-2017 IPR000030 PPE family BWK49_RS15255 bf2328900671eed4554aa59daf62d212 403 SUPERFAMILY SSF140459 3 175 3.66E-59 T 06-07-2017 BWK49_RS19815 a4945a94657e0916702c4355b28b09f1 751 SUPERFAMILY SSF54211 325 526 2.28E-43 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold BWK49_RS19815 a4945a94657e0916702c4355b28b09f1 751 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 22 730 7.3E-268 T 06-07-2017 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 BWK49_RS19815 a4945a94657e0916702c4355b28b09f1 751 PIRSF PIRSF005499 12 750 3.3E-291 T 06-07-2017 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 BWK49_RS19815 a4945a94657e0916702c4355b28b09f1 751 SUPERFAMILY SSF55666 481 584 3.44E-22 T 06-07-2017 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 BWK49_RS19815 a4945a94657e0916702c4355b28b09f1 751 SMART SM00322 590 655 7.3E-11 T 06-07-2017 IPR004087 K Homology domain GO:0003676 BWK49_RS19815 a4945a94657e0916702c4355b28b09f1 751 TIGRFAM TIGR02696 pppGpp_PNP: guanosine pentaphosphate synthetase I/polyribonucleotide nucleotidyltransferase 10 729 0.0 T 06-07-2017 IPR014069 Guanosine pentaphosphate synthetase I/polyribonucleotide nucleotidyltransferase GO:0004654|GO:0005737|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 BWK49_RS19815 a4945a94657e0916702c4355b28b09f1 751 Gene3D G3DSA:3.30.230.70 12 252 2.2E-85 T 06-07-2017 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 BWK49_RS19815 a4945a94657e0916702c4355b28b09f1 751 Gene3D G3DSA:3.30.230.70 343 581 1.8E-79 T 06-07-2017 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 BWK49_RS19815 a4945a94657e0916702c4355b28b09f1 751 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 271 350 9.7E-21 T 06-07-2017 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 BWK49_RS19815 a4945a94657e0916702c4355b28b09f1 751 Gene3D G3DSA:3.30.1370.10 589 662 4.7E-23 T 06-07-2017 IPR004088 K Homology domain, type 1 GO:0003723 BWK49_RS19815 a4945a94657e0916702c4355b28b09f1 751 SUPERFAMILY SSF50249 659 728 6.12E-15 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS19815 a4945a94657e0916702c4355b28b09f1 751 SUPERFAMILY SSF46915 269 351 2.38E-16 T 06-07-2017 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 BWK49_RS19815 a4945a94657e0916702c4355b28b09f1 751 SMART SM00316 660 731 4.6E-17 T 06-07-2017 IPR022967 RNA-binding domain, S1 BWK49_RS19815 a4945a94657e0916702c4355b28b09f1 751 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 14 734 27.12 T 06-07-2017 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 BWK49_RS19815 a4945a94657e0916702c4355b28b09f1 751 Pfam PF03725 3' exoribonuclease family, domain 2 159 236 2.6E-5 T 06-07-2017 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 BWK49_RS19815 a4945a94657e0916702c4355b28b09f1 751 Pfam PF00575 S1 RNA binding domain 659 728 7.8E-14 T 06-07-2017 IPR003029 S1 domain GO:0003676 BWK49_RS19815 a4945a94657e0916702c4355b28b09f1 751 SUPERFAMILY SSF54211 14 156 7.59E-45 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold BWK49_RS19815 a4945a94657e0916702c4355b28b09f1 751 Gene3D G3DSA:2.40.50.140 663 728 1.2E-18 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS19815 a4945a94657e0916702c4355b28b09f1 751 SUPERFAMILY SSF55666 157 264 8.83E-28 T 06-07-2017 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 BWK49_RS19815 a4945a94657e0916702c4355b28b09f1 751 SUPERFAMILY SSF54791 593 679 2.37E-18 T 06-07-2017 IPR004088 K Homology domain, type 1 GO:0003723 BWK49_RS19815 a4945a94657e0916702c4355b28b09f1 751 Gene3D G3DSA:1.10.10.400 268 342 2.9E-23 T 06-07-2017 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 BWK49_RS19815 a4945a94657e0916702c4355b28b09f1 751 Pfam PF00013 KH domain 594 651 2.0E-10 T 06-07-2017 IPR004088 K Homology domain, type 1 GO:0003723 BWK49_RS19815 a4945a94657e0916702c4355b28b09f1 751 Pfam PF01138 3' exoribonuclease family, domain 1 25 156 7.8E-17 T 06-07-2017 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 BWK49_RS19815 a4945a94657e0916702c4355b28b09f1 751 Pfam PF01138 3' exoribonuclease family, domain 1 355 487 1.3E-15 T 06-07-2017 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 BWK49_RS11585 1cc9b3b54ed289d684cbfb22046d6f20 1413 Gene3D G3DSA:3.40.50.360 860 1009 5.2E-45 T 06-07-2017 IPR029039 Flavoprotein-like domain BWK49_RS11585 1cc9b3b54ed289d684cbfb22046d6f20 1413 SUPERFAMILY SSF52218 862 1008 3.09E-44 T 06-07-2017 IPR029039 Flavoprotein-like domain BWK49_RS11585 1cc9b3b54ed289d684cbfb22046d6f20 1413 Pfam PF00667 FAD binding domain 1044 1239 7.0E-32 T 06-07-2017 IPR003097 FAD-binding, type 1 GO:0016491|GO:0055114 BWK49_RS11585 1cc9b3b54ed289d684cbfb22046d6f20 1413 Pfam PF01568 Molydopterin dinucleotide binding domain 606 717 1.3E-36 T 06-07-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 BWK49_RS11585 1cc9b3b54ed289d684cbfb22046d6f20 1413 Gene3D G3DSA:2.40.30.10 1199 1268 4.9E-38 T 06-07-2017 BWK49_RS11585 1cc9b3b54ed289d684cbfb22046d6f20 1413 Gene3D G3DSA:2.40.30.10 1041 1092 4.9E-38 T 06-07-2017 BWK49_RS11585 1cc9b3b54ed289d684cbfb22046d6f20 1413 Gene3D G3DSA:3.40.228.10 143 322 1.2E-66 T 06-07-2017 BWK49_RS11585 1cc9b3b54ed289d684cbfb22046d6f20 1413 SMART SM00926 4 64 8.3E-16 T 06-07-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS11585 1cc9b3b54ed289d684cbfb22046d6f20 1413 SUPERFAMILY SSF50692 578 723 6.1E-50 T 06-07-2017 IPR009010 Aspartate decarboxylase-like domain BWK49_RS11585 1cc9b3b54ed289d684cbfb22046d6f20 1413 SUPERFAMILY SSF52343 1258 1413 2.88E-51 T 06-07-2017 BWK49_RS11585 1cc9b3b54ed289d684cbfb22046d6f20 1413 Gene3D G3DSA:3.40.50.80 1269 1412 7.7E-58 T 06-07-2017 BWK49_RS11585 1cc9b3b54ed289d684cbfb22046d6f20 1413 Pfam PF00384 Molybdopterin oxidoreductase 80 494 1.3E-70 T 06-07-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS11585 1cc9b3b54ed289d684cbfb22046d6f20 1413 SUPERFAMILY SSF63380 1041 1260 1.83E-62 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 BWK49_RS11585 1cc9b3b54ed289d684cbfb22046d6f20 1413 Pfam PF00175 Oxidoreductase NAD-binding domain 1271 1377 8.0E-17 T 06-07-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 BWK49_RS11585 1cc9b3b54ed289d684cbfb22046d6f20 1413 SUPERFAMILY SSF53706 4 608 2.62E-187 T 06-07-2017 BWK49_RS11585 1cc9b3b54ed289d684cbfb22046d6f20 1413 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 1295 1304 3.6E-27 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 BWK49_RS11585 1cc9b3b54ed289d684cbfb22046d6f20 1413 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 1339 1355 3.6E-27 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 BWK49_RS11585 1cc9b3b54ed289d684cbfb22046d6f20 1413 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 1362 1370 3.6E-27 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 BWK49_RS11585 1cc9b3b54ed289d684cbfb22046d6f20 1413 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 1082 1092 3.6E-27 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 BWK49_RS11585 1cc9b3b54ed289d684cbfb22046d6f20 1413 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 1308 1319 3.6E-27 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 BWK49_RS11585 1cc9b3b54ed289d684cbfb22046d6f20 1413 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 1270 1289 3.6E-27 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 BWK49_RS11585 1cc9b3b54ed289d684cbfb22046d6f20 1413 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 1234 1243 3.6E-27 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 BWK49_RS11585 1cc9b3b54ed289d684cbfb22046d6f20 1413 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 1201 1208 3.6E-27 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 BWK49_RS11585 1cc9b3b54ed289d684cbfb22046d6f20 1413 PRINTS PR00369 Flavodoxin signature 915 926 3.5E-10 T 06-07-2017 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 BWK49_RS11585 1cc9b3b54ed289d684cbfb22046d6f20 1413 PRINTS PR00369 Flavodoxin signature 947 957 3.5E-10 T 06-07-2017 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 BWK49_RS11585 1cc9b3b54ed289d684cbfb22046d6f20 1413 PRINTS PR00369 Flavodoxin signature 971 990 3.5E-10 T 06-07-2017 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 BWK49_RS11585 1cc9b3b54ed289d684cbfb22046d6f20 1413 PRINTS PR00369 Flavodoxin signature 867 880 3.5E-10 T 06-07-2017 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 BWK49_RS11585 1cc9b3b54ed289d684cbfb22046d6f20 1413 Gene3D G3DSA:3.40.50.740 68 141 9.6E-69 T 06-07-2017 BWK49_RS11585 1cc9b3b54ed289d684cbfb22046d6f20 1413 Gene3D G3DSA:3.40.50.740 381 538 9.6E-69 T 06-07-2017 BWK49_RS11585 1cc9b3b54ed289d684cbfb22046d6f20 1413 Gene3D G3DSA:3.40.50.740 323 345 9.6E-69 T 06-07-2017 BWK49_RS11585 1cc9b3b54ed289d684cbfb22046d6f20 1413 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 645 672 - T 06-07-2017 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 BWK49_RS11585 1cc9b3b54ed289d684cbfb22046d6f20 1413 Gene3D G3DSA:2.20.25.90 3 64 6.2E-16 T 06-07-2017 BWK49_RS11585 1cc9b3b54ed289d684cbfb22046d6f20 1413 Gene3D G3DSA:1.20.990.10 1093 1198 1.4E-25 T 06-07-2017 IPR023173 NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain-3 GO:0016491|GO:0055114 BWK49_RS11585 1cc9b3b54ed289d684cbfb22046d6f20 1413 Gene3D G3DSA:2.40.40.20 539 723 2.4E-59 T 06-07-2017 BWK49_RS11585 1cc9b3b54ed289d684cbfb22046d6f20 1413 Pfam PF00258 Flavodoxin 868 999 1.7E-26 T 06-07-2017 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 BWK49_RS11585 1cc9b3b54ed289d684cbfb22046d6f20 1413 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 6 60 5.3E-13 T 06-07-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS11585 1cc9b3b54ed289d684cbfb22046d6f20 1413 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 9 27 - T 06-07-2017 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 KEGG: 00910+1.7.99.4 BWK49_RS06690 bda7f796125bb665ac157af0c05ce2aa 373 Gene3D G3DSA:1.10.230.10 227 311 3.2E-22 T 06-07-2017 IPR016143 Citrate synthase-like, small alpha subdomain Reactome: R-HSA-163765|Reactome: R-HSA-75105 BWK49_RS06690 bda7f796125bb665ac157af0c05ce2aa 373 Pfam PF00285 Citrate synthase, C-terminal domain 11 60 1.8E-9 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 BWK49_RS06690 bda7f796125bb665ac157af0c05ce2aa 373 Pfam PF00285 Citrate synthase, C-terminal domain 108 348 1.6E-71 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 BWK49_RS06690 bda7f796125bb665ac157af0c05ce2aa 373 SUPERFAMILY SSF48256 7 359 1.57E-94 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 BWK49_RS06690 bda7f796125bb665ac157af0c05ce2aa 373 ProSitePatterns PS00480 Citrate synthase signature. 247 259 - T 06-07-2017 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 BWK49_RS06690 bda7f796125bb665ac157af0c05ce2aa 373 Gene3D G3DSA:1.10.580.10 17 226 1.4E-44 T 06-07-2017 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 BWK49_RS06690 bda7f796125bb665ac157af0c05ce2aa 373 PRINTS PR00143 Citrate synthase signature 165 180 1.2E-24 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 BWK49_RS06690 bda7f796125bb665ac157af0c05ce2aa 373 PRINTS PR00143 Citrate synthase signature 240 260 1.2E-24 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 BWK49_RS06690 bda7f796125bb665ac157af0c05ce2aa 373 PRINTS PR00143 Citrate synthase signature 319 333 1.2E-24 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 BWK49_RS06690 bda7f796125bb665ac157af0c05ce2aa 373 PRINTS PR00143 Citrate synthase signature 299 315 1.2E-24 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 BWK49_RS06690 bda7f796125bb665ac157af0c05ce2aa 373 PRINTS PR00143 Citrate synthase signature 187 215 1.2E-24 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 BWK49_RS27765 ab57186b234ba0fa3492bb1ddef4307d 664 Pfam PF01757 Acyltransferase family 20 373 6.5E-22 T 06-07-2017 IPR002656 Acyltransferase 3 GO:0016747 BWK49_RS27765 ab57186b234ba0fa3492bb1ddef4307d 664 Gene3D G3DSA:3.40.50.1110 445 661 2.8E-10 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain BWK49_RS27765 ab57186b234ba0fa3492bb1ddef4307d 664 SUPERFAMILY SSF52266 450 663 6.96E-17 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain BWK49_RS09190 62a0f3ff4ce8d9df2087fab86d4e4cfc 273 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 157 185 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS09190 62a0f3ff4ce8d9df2087fab86d4e4cfc 273 SUPERFAMILY SSF51735 3 272 6.87E-68 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS09190 62a0f3ff4ce8d9df2087fab86d4e4cfc 273 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 271 6.8E-47 T 06-07-2017 BWK49_RS09190 62a0f3ff4ce8d9df2087fab86d4e4cfc 273 TIGRFAM TIGR03971 SDR_subfam_1: SDR family mycofactocin-dependent oxidoreductase 5 272 1.0E-102 T 06-07-2017 IPR023985 Mycofactocin-dependent oxidoreductase BWK49_RS09190 62a0f3ff4ce8d9df2087fab86d4e4cfc 273 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 96 107 1.1E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS09190 62a0f3ff4ce8d9df2087fab86d4e4cfc 273 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 158 1.1E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS09190 62a0f3ff4ce8d9df2087fab86d4e4cfc 273 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 170 189 1.1E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS09190 62a0f3ff4ce8d9df2087fab86d4e4cfc 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 96 107 2.3E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS09190 62a0f3ff4ce8d9df2087fab86d4e4cfc 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 234 254 2.3E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS09190 62a0f3ff4ce8d9df2087fab86d4e4cfc 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 189 2.3E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS09190 62a0f3ff4ce8d9df2087fab86d4e4cfc 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 191 208 2.3E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS09190 62a0f3ff4ce8d9df2087fab86d4e4cfc 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 160 2.3E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS09190 62a0f3ff4ce8d9df2087fab86d4e4cfc 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 2.3E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS09190 62a0f3ff4ce8d9df2087fab86d4e4cfc 273 Gene3D G3DSA:3.40.50.720 2 271 4.5E-71 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS08785 2775e59318c823576a1c6a7eefb4140e 302 SUPERFAMILY SSF161098 88 277 9.94E-19 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS08785 2775e59318c823576a1c6a7eefb4140e 302 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 21 69 5.9E-7 T 06-07-2017 IPR025966 Oligopeptide transport permease C-like, N-terminal domain BWK49_RS08785 2775e59318c823576a1c6a7eefb4140e 302 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 293 1.6E-23 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS08785 2775e59318c823576a1c6a7eefb4140e 302 Gene3D G3DSA:1.10.3720.10 86 292 1.6E-19 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS22750 d9fc44ca0b31f440ffb2b99b89c9343c 499 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 396 490 1.5E-8 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS22750 d9fc44ca0b31f440ffb2b99b89c9343c 499 Gene3D G3DSA:3.30.565.10 353 492 2.5E-18 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS22750 d9fc44ca0b31f440ffb2b99b89c9343c 499 Pfam PF12282 Signal transduction histidine kinase 4 149 4.7E-45 T 06-07-2017 IPR022066 Signal transduction histidine kinase BWK49_RS22750 d9fc44ca0b31f440ffb2b99b89c9343c 499 Pfam PF07568 Histidine kinase 298 365 1.2E-21 T 06-07-2017 IPR011495 Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain BWK49_RS22750 d9fc44ca0b31f440ffb2b99b89c9343c 499 SUPERFAMILY SSF55874 355 490 4.06E-17 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS22750 d9fc44ca0b31f440ffb2b99b89c9343c 499 SUPERFAMILY SSF55785 178 289 1.39E-5 T 06-07-2017 IPR000014 PAS domain BWK49_RS22750 d9fc44ca0b31f440ffb2b99b89c9343c 499 SMART SM00387 392 493 3.7E-8 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS22750 d9fc44ca0b31f440ffb2b99b89c9343c 499 Gene3D G3DSA:3.30.450.20 177 280 1.2E-6 T 06-07-2017 BWK49_RS22750 d9fc44ca0b31f440ffb2b99b89c9343c 499 Pfam PF08448 PAS fold 176 284 1.4E-5 T 06-07-2017 IPR013656 PAS fold-4 BWK49_RS14570 5881cfb66e05b601903c9e6de7c68ae5 108 SUPERFAMILY SSF46785 8 101 1.36E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS14570 5881cfb66e05b601903c9e6de7c68ae5 108 Gene3D G3DSA:1.10.10.10 8 106 1.3E-31 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS14570 5881cfb66e05b601903c9e6de7c68ae5 108 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 12 27 5.2E-8 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 BWK49_RS14570 5881cfb66e05b601903c9e6de7c68ae5 108 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 44 59 5.2E-8 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 BWK49_RS14570 5881cfb66e05b601903c9e6de7c68ae5 108 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 59 74 5.2E-8 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 BWK49_RS14570 5881cfb66e05b601903c9e6de7c68ae5 108 Pfam PF12840 Helix-turn-helix domain 9 68 2.0E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS14570 5881cfb66e05b601903c9e6de7c68ae5 108 SMART SM00418 10 88 1.5E-23 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 BWK49_RS17305 e5298892519ef8563596db214a58fed8 262 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 8 262 1.1E-114 T 06-07-2017 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 BWK49_RS17305 e5298892519ef8563596db214a58fed8 262 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 7 262 48.26 T 06-07-2017 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 BWK49_RS17305 e5298892519ef8563596db214a58fed8 262 Gene3D G3DSA:3.20.20.70 11 262 1.4E-105 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 BWK49_RS17305 e5298892519ef8563596db214a58fed8 262 SUPERFAMILY SSF51366 9 262 5.65E-82 T 06-07-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 BWK49_RS17305 e5298892519ef8563596db214a58fed8 262 Pfam PF00977 Histidine biosynthesis protein 11 246 5.9E-87 T 06-07-2017 IPR006062 Histidine biosynthesis GO:0000105 BWK49_RS08005 34cb4642d70f1d95abc4823d1aaf5851 525 SUPERFAMILY SSF52009 337 447 3.14E-28 T 06-07-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 BWK49_RS08005 34cb4642d70f1d95abc4823d1aaf5851 525 Pfam PF00391 PEP-utilising enzyme, mobile domain 372 441 8.4E-21 T 06-07-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 BWK49_RS08005 34cb4642d70f1d95abc4823d1aaf5851 525 SUPERFAMILY SSF56059 1 325 1.88E-97 T 06-07-2017 BWK49_RS08005 34cb4642d70f1d95abc4823d1aaf5851 525 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 253 306 8.9E-5 T 06-07-2017 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 BWK49_RS08005 34cb4642d70f1d95abc4823d1aaf5851 525 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 13 250 3.2E-28 T 06-07-2017 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 BWK49_RS08005 34cb4642d70f1d95abc4823d1aaf5851 525 Gene3D G3DSA:3.30.470.20 194 290 3.2E-27 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 BWK49_RS08005 34cb4642d70f1d95abc4823d1aaf5851 525 Gene3D G3DSA:1.10.189.10 292 353 3.4E-19 T 06-07-2017 BWK49_RS08005 34cb4642d70f1d95abc4823d1aaf5851 525 Gene3D G3DSA:3.30.1490.20 3 106 8.3E-45 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 BWK49_RS08005 34cb4642d70f1d95abc4823d1aaf5851 525 Gene3D G3DSA:3.30.1490.20 150 193 8.3E-45 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 BWK49_RS08005 34cb4642d70f1d95abc4823d1aaf5851 525 Gene3D G3DSA:3.50.30.10 354 443 2.7E-26 T 06-07-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 BWK49_RS16955 4b252bd3b8eb5021bedf6f221857e9dc 308 PRINTS PR00102 Ornithine carbamoyltransferase signature 117 131 5.9E-30 T 06-07-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 BWK49_RS16955 4b252bd3b8eb5021bedf6f221857e9dc 308 PRINTS PR00102 Ornithine carbamoyltransferase signature 77 90 5.9E-30 T 06-07-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 BWK49_RS16955 4b252bd3b8eb5021bedf6f221857e9dc 308 PRINTS PR00102 Ornithine carbamoyltransferase signature 221 231 5.9E-30 T 06-07-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 BWK49_RS16955 4b252bd3b8eb5021bedf6f221857e9dc 308 PRINTS PR00102 Ornithine carbamoyltransferase signature 283 294 5.9E-30 T 06-07-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 BWK49_RS16955 4b252bd3b8eb5021bedf6f221857e9dc 308 PRINTS PR00102 Ornithine carbamoyltransferase signature 44 58 5.9E-30 T 06-07-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 BWK49_RS16955 4b252bd3b8eb5021bedf6f221857e9dc 308 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 3 304 2.8E-116 T 06-07-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 BWK49_RS16955 4b252bd3b8eb5021bedf6f221857e9dc 308 SUPERFAMILY SSF53671 2 306 7.2E-101 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 BWK49_RS16955 4b252bd3b8eb5021bedf6f221857e9dc 308 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 257 266 3.6E-28 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 BWK49_RS16955 4b252bd3b8eb5021bedf6f221857e9dc 308 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 128 139 3.6E-28 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 BWK49_RS16955 4b252bd3b8eb5021bedf6f221857e9dc 308 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 269 292 3.6E-28 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 BWK49_RS16955 4b252bd3b8eb5021bedf6f221857e9dc 308 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 46 65 3.6E-28 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 BWK49_RS16955 4b252bd3b8eb5021bedf6f221857e9dc 308 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 46 53 - T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 BWK49_RS16955 4b252bd3b8eb5021bedf6f221857e9dc 308 Gene3D G3DSA:3.40.50.1370 3 138 6.7E-51 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 BWK49_RS16955 4b252bd3b8eb5021bedf6f221857e9dc 308 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 3 141 2.6E-47 T 06-07-2017 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 BWK49_RS16955 4b252bd3b8eb5021bedf6f221857e9dc 308 Gene3D G3DSA:3.40.50.1370 139 291 2.2E-60 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 BWK49_RS16955 4b252bd3b8eb5021bedf6f221857e9dc 308 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 2 305 77.866 T 06-07-2017 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 BWK49_RS16955 4b252bd3b8eb5021bedf6f221857e9dc 308 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 148 302 3.1E-53 T 06-07-2017 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 BWK49_RS08110 a2e8f109fa93f9ee633faee56312a5d0 382 PIRSF PIRSF000429 1 382 1.0E-125 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 BWK49_RS08110 a2e8f109fa93f9ee633faee56312a5d0 382 Pfam PF00108 Thiolase, N-terminal domain 5 251 7.5E-72 T 06-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 BWK49_RS08110 a2e8f109fa93f9ee633faee56312a5d0 382 SUPERFAMILY SSF53901 3 259 1.1E-73 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS08110 a2e8f109fa93f9ee633faee56312a5d0 382 Gene3D G3DSA:3.40.47.10 266 381 1.3E-54 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS08110 a2e8f109fa93f9ee633faee56312a5d0 382 Gene3D G3DSA:3.40.47.10 149 186 1.3E-54 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS08110 a2e8f109fa93f9ee633faee56312a5d0 382 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 380 2.4E-135 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 BWK49_RS08110 a2e8f109fa93f9ee633faee56312a5d0 382 SUPERFAMILY SSF53901 260 381 5.27E-41 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS08110 a2e8f109fa93f9ee633faee56312a5d0 382 ProSitePatterns PS00737 Thiolases signature 2. 328 344 - T 06-07-2017 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 BWK49_RS08110 a2e8f109fa93f9ee633faee56312a5d0 382 Gene3D G3DSA:3.40.47.10 187 265 1.7E-69 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS08110 a2e8f109fa93f9ee633faee56312a5d0 382 Gene3D G3DSA:3.40.47.10 4 124 1.7E-69 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS08110 a2e8f109fa93f9ee633faee56312a5d0 382 Pfam PF02803 Thiolase, C-terminal domain 259 380 2.6E-43 T 06-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 BWK49_RS18380 e05366873ef4f21c0bac2de0a913e66d 445 Gene3D G3DSA:1.10.940.10 3 159 3.6E-42 T 06-07-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 BWK49_RS18380 e05366873ef4f21c0bac2de0a913e66d 445 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 323 334 - T 06-07-2017 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 BWK49_RS18380 e05366873ef4f21c0bac2de0a913e66d 445 SUPERFAMILY SSF48013 3 158 3.79E-31 T 06-07-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 BWK49_RS18380 e05366873ef4f21c0bac2de0a913e66d 445 Pfam PF01029 NusB family 3 124 8.5E-24 T 06-07-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 BWK49_RS18380 e05366873ef4f21c0bac2de0a913e66d 445 Gene3D G3DSA:3.40.50.150 238 443 6.5E-46 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS18380 e05366873ef4f21c0bac2de0a913e66d 445 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 261 271 8.9E-23 T 06-07-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 BWK49_RS18380 e05366873ef4f21c0bac2de0a913e66d 445 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 425 442 8.9E-23 T 06-07-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 BWK49_RS18380 e05366873ef4f21c0bac2de0a913e66d 445 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 374 390 8.9E-23 T 06-07-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 BWK49_RS18380 e05366873ef4f21c0bac2de0a913e66d 445 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 228 242 8.9E-23 T 06-07-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 BWK49_RS18380 e05366873ef4f21c0bac2de0a913e66d 445 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 324 336 8.9E-23 T 06-07-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 BWK49_RS18380 e05366873ef4f21c0bac2de0a913e66d 445 Pfam PF01189 16S rRNA methyltransferase RsmB/F 248 441 1.1E-59 T 06-07-2017 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 BWK49_RS18380 e05366873ef4f21c0bac2de0a913e66d 445 SUPERFAMILY SSF53335 145 442 3.07E-55 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS19345 2eb6c32c96655830552d1aaea69e6cf4 301 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 BWK49_RS19345 2eb6c32c96655830552d1aaea69e6cf4 301 SMART SM00382 44 222 5.9E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS19345 2eb6c32c96655830552d1aaea69e6cf4 301 Gene3D G3DSA:3.40.50.300 14 235 6.8E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS19345 2eb6c32c96655830552d1aaea69e6cf4 301 SUPERFAMILY SSF52540 16 234 1.81E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS19345 2eb6c32c96655830552d1aaea69e6cf4 301 Pfam PF00005 ABC transporter 36 175 5.3E-22 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 BWK49_RS19045 2c306fca8dd2fb8edac09f9dca7585c9 247 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 12 198 8.2E-27 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal BWK49_RS19045 2c306fca8dd2fb8edac09f9dca7585c9 247 Gene3D G3DSA:3.40.225.10 6 218 6.9E-34 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal BWK49_RS19045 2c306fca8dd2fb8edac09f9dca7585c9 247 SUPERFAMILY SSF53639 5 218 1.9E-36 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal BWK49_RS19045 2c306fca8dd2fb8edac09f9dca7585c9 247 SMART SM01007 10 198 2.9E-20 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal BWK49_RS04075 b01579beed9ad427d530aa3fea2acf58 364 Gene3D G3DSA:3.30.70.1400 41 122 1.4E-9 T 06-07-2017 BWK49_RS04075 b01579beed9ad427d530aa3fea2acf58 364 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 250 323 8.7E-7 T 06-07-2017 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 BWK49_RS04075 b01579beed9ad427d530aa3fea2acf58 364 Pfam PF01571 Aminomethyltransferase folate-binding domain 19 236 1.2E-24 T 06-07-2017 IPR006222 Glycine cleavage T-protein-like, N-terminal BWK49_RS04075 b01579beed9ad427d530aa3fea2acf58 364 PIRSF PIRSF006487 14 329 1.2E-15 T 06-07-2017 IPR028896 Aminomethyltransferase/Dimethylsulfonioproprionate demethylase DmdA KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 BWK49_RS04075 b01579beed9ad427d530aa3fea2acf58 364 TIGRFAM TIGR03317 ygfZ_signature: folate-binding protein YgfZ 208 276 3.3E-19 T 06-07-2017 IPR017703 YgfZ/GcvT conserved site BWK49_RS04075 b01579beed9ad427d530aa3fea2acf58 364 SUPERFAMILY SSF103025 17 265 4.87E-58 T 06-07-2017 BWK49_RS16760 bfe1f109be844b474e8be24015272430 233 SMART SM01012 155 210 6.9E-17 T 06-07-2017 IPR005561 ANTAR domain GO:0003723 BWK49_RS16760 bfe1f109be844b474e8be24015272430 233 Pfam PF08447 PAS fold 58 127 3.0E-11 T 06-07-2017 IPR013655 PAS fold-3 GO:0005515 BWK49_RS16760 bfe1f109be844b474e8be24015272430 233 Gene3D G3DSA:3.30.450.20 16 148 9.4E-17 T 06-07-2017 BWK49_RS16760 bfe1f109be844b474e8be24015272430 233 SUPERFAMILY SSF55785 48 149 6.28E-14 T 06-07-2017 IPR000014 PAS domain BWK49_RS16760 bfe1f109be844b474e8be24015272430 233 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 53 150 2.1E-7 T 06-07-2017 IPR000014 PAS domain BWK49_RS16760 bfe1f109be844b474e8be24015272430 233 Gene3D G3DSA:1.10.10.10 164 213 1.9E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS16760 bfe1f109be844b474e8be24015272430 233 Pfam PF03861 ANTAR domain 163 207 1.6E-15 T 06-07-2017 IPR005561 ANTAR domain GO:0003723 BWK49_RS24120 bcbad5a92fbac2bcd674dd30482bcf48 168 SMART SM00347 50 151 2.0E-22 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 BWK49_RS24120 bcbad5a92fbac2bcd674dd30482bcf48 168 Gene3D G3DSA:1.10.10.10 16 166 2.1E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS24120 bcbad5a92fbac2bcd674dd30482bcf48 168 Pfam PF01047 MarR family 61 116 7.0E-9 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 BWK49_RS24120 bcbad5a92fbac2bcd674dd30482bcf48 168 SUPERFAMILY SSF46785 32 165 3.06E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS12275 1c0ed0469a2fbf49c6f2d2500582cdec 422 Pfam PF00067 Cytochrome P450 172 380 9.0E-23 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS12275 1c0ed0469a2fbf49c6f2d2500582cdec 422 SUPERFAMILY SSF48264 17 412 3.41E-80 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS12275 1c0ed0469a2fbf49c6f2d2500582cdec 422 Gene3D G3DSA:1.10.630.10 14 413 1.2E-96 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS12275 1c0ed0469a2fbf49c6f2d2500582cdec 422 PRINTS PR00359 B-class P450 signature 101 112 4.9E-32 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS12275 1c0ed0469a2fbf49c6f2d2500582cdec 422 PRINTS PR00359 B-class P450 signature 351 360 4.9E-32 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS12275 1c0ed0469a2fbf49c6f2d2500582cdec 422 PRINTS PR00359 B-class P450 signature 164 179 4.9E-32 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS12275 1c0ed0469a2fbf49c6f2d2500582cdec 422 PRINTS PR00359 B-class P450 signature 330 345 4.9E-32 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS12275 1c0ed0469a2fbf49c6f2d2500582cdec 422 PRINTS PR00359 B-class P450 signature 204 226 4.9E-32 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS12275 1c0ed0469a2fbf49c6f2d2500582cdec 422 PRINTS PR00359 B-class P450 signature 302 329 4.9E-32 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS12275 1c0ed0469a2fbf49c6f2d2500582cdec 422 PRINTS PR00359 B-class P450 signature 285 296 4.9E-32 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS12275 1c0ed0469a2fbf49c6f2d2500582cdec 422 PRINTS PR00359 B-class P450 signature 360 371 4.9E-32 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS12275 1c0ed0469a2fbf49c6f2d2500582cdec 422 PRINTS PR00359 B-class P450 signature 147 163 4.9E-32 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS12275 1c0ed0469a2fbf49c6f2d2500582cdec 422 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 353 362 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 BWK49_RS24020 5068a9d24c4512125ff4483074c69312 37 Pfam PF00444 Ribosomal protein L36 2 37 4.6E-17 T 06-07-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS24020 5068a9d24c4512125ff4483074c69312 37 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 36 - T 06-07-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS24020 5068a9d24c4512125ff4483074c69312 37 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 10 37 4.0E-9 T 06-07-2017 BWK49_RS24020 5068a9d24c4512125ff4483074c69312 37 SUPERFAMILY SSF57840 2 37 6.93E-16 T 06-07-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS24020 5068a9d24c4512125ff4483074c69312 37 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 2 37 1.2E-20 T 06-07-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS24020 5068a9d24c4512125ff4483074c69312 37 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 37 16.573 T 06-07-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS26125 bc21db7b36fd4c765f40cbf6f65635ef 619 SUPERFAMILY SSF53067 162 356 5.51E-64 T 06-07-2017 BWK49_RS26125 bc21db7b36fd4c765f40cbf6f65635ef 619 Gene3D G3DSA:2.60.34.10 364 506 4.7E-76 T 06-07-2017 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 BWK49_RS26125 bc21db7b36fd4c765f40cbf6f65635ef 619 Gene3D G3DSA:3.30.30.30 39 100 2.4E-17 T 06-07-2017 BWK49_RS26125 bc21db7b36fd4c765f40cbf6f65635ef 619 PRINTS PR00301 70kDa heat shock protein signature 339 359 2.8E-76 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 BWK49_RS26125 bc21db7b36fd4c765f40cbf6f65635ef 619 PRINTS PR00301 70kDa heat shock protein signature 54 62 2.8E-76 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 BWK49_RS26125 bc21db7b36fd4c765f40cbf6f65635ef 619 PRINTS PR00301 70kDa heat shock protein signature 114 134 2.8E-76 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 BWK49_RS26125 bc21db7b36fd4c765f40cbf6f65635ef 619 PRINTS PR00301 70kDa heat shock protein signature 443 459 2.8E-76 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 BWK49_RS26125 bc21db7b36fd4c765f40cbf6f65635ef 619 PRINTS PR00301 70kDa heat shock protein signature 362 381 2.8E-76 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 BWK49_RS26125 bc21db7b36fd4c765f40cbf6f65635ef 619 PRINTS PR00301 70kDa heat shock protein signature 3 16 2.8E-76 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 BWK49_RS26125 bc21db7b36fd4c765f40cbf6f65635ef 619 PRINTS PR00301 70kDa heat shock protein signature 31 43 2.8E-76 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 BWK49_RS26125 bc21db7b36fd4c765f40cbf6f65635ef 619 PRINTS PR00301 70kDa heat shock protein signature 307 323 2.8E-76 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 BWK49_RS26125 bc21db7b36fd4c765f40cbf6f65635ef 619 PRINTS PR00301 70kDa heat shock protein signature 174 184 2.8E-76 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 BWK49_RS26125 bc21db7b36fd4c765f40cbf6f65635ef 619 Gene3D G3DSA:3.30.420.40 167 201 5.7E-35 T 06-07-2017 BWK49_RS26125 bc21db7b36fd4c765f40cbf6f65635ef 619 Gene3D G3DSA:3.30.420.40 292 334 5.7E-35 T 06-07-2017 BWK49_RS26125 bc21db7b36fd4c765f40cbf6f65635ef 619 SUPERFAMILY SSF100934 481 583 1.7E-14 T 06-07-2017 IPR029048 Heat shock protein 70kD, C-terminal domain Reactome: R-HSA-3371453 BWK49_RS26125 bc21db7b36fd4c765f40cbf6f65635ef 619 Pfam PF00012 Hsp70 protein 83 583 5.0E-220 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 BWK49_RS26125 bc21db7b36fd4c765f40cbf6f65635ef 619 Pfam PF00012 Hsp70 protein 4 78 8.4E-29 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 BWK49_RS26125 bc21db7b36fd4c765f40cbf6f65635ef 619 Gene3D G3DSA:3.30.420.40 4 38 2.1E-57 T 06-07-2017 BWK49_RS26125 bc21db7b36fd4c765f40cbf6f65635ef 619 Gene3D G3DSA:3.30.420.40 101 166 2.1E-57 T 06-07-2017 BWK49_RS26125 bc21db7b36fd4c765f40cbf6f65635ef 619 Gene3D G3DSA:3.90.640.10 202 288 3.0E-28 T 06-07-2017 BWK49_RS26125 bc21db7b36fd4c765f40cbf6f65635ef 619 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 4 582 1.0E-276 T 06-07-2017 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453 BWK49_RS26125 bc21db7b36fd4c765f40cbf6f65635ef 619 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 06-07-2017 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 BWK49_RS26125 bc21db7b36fd4c765f40cbf6f65635ef 619 Gene3D G3DSA:1.20.1270.10 507 582 1.3E-25 T 06-07-2017 IPR029048 Heat shock protein 70kD, C-terminal domain Reactome: R-HSA-3371453 BWK49_RS26125 bc21db7b36fd4c765f40cbf6f65635ef 619 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 310 324 - T 06-07-2017 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 BWK49_RS26125 bc21db7b36fd4c765f40cbf6f65635ef 619 SUPERFAMILY SSF100920 358 514 1.44E-64 T 06-07-2017 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 BWK49_RS26125 bc21db7b36fd4c765f40cbf6f65635ef 619 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 614 36.43 T 06-07-2017 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453 BWK49_RS26125 bc21db7b36fd4c765f40cbf6f65635ef 619 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 168 181 - T 06-07-2017 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 BWK49_RS26125 bc21db7b36fd4c765f40cbf6f65635ef 619 SUPERFAMILY SSF53067 3 159 3.17E-58 T 06-07-2017 BWK49_RS27545 90891978ddceaa7245cd4f83bf97777e 70 Gene3D G3DSA:2.40.50.100 1 70 2.0E-23 T 06-07-2017 BWK49_RS27545 90891978ddceaa7245cd4f83bf97777e 70 SUPERFAMILY SSF50331 1 70 7.29E-20 T 06-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal BWK49_RS27545 90891978ddceaa7245cd4f83bf97777e 70 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 1 69 1.3E-19 T 06-07-2017 IPR004606 Molybdenum-pterin binding GO:0006810|GO:0030151 BWK49_RS27545 90891978ddceaa7245cd4f83bf97777e 70 Pfam PF03459 TOBE domain 4 66 4.1E-18 T 06-07-2017 IPR005116 Transport-associated OB, type 1 BWK49_RS22950 e22b57c04fd10df13ae4b4f249b6de2e 61 PRINTS PR00163 Rubredoxin signature 37 53 5.3E-8 T 06-07-2017 IPR024935 Rubredoxin domain GO:0005506 BWK49_RS22950 e22b57c04fd10df13ae4b4f249b6de2e 61 PRINTS PR00163 Rubredoxin signature 7 23 5.3E-8 T 06-07-2017 IPR024935 Rubredoxin domain GO:0005506 BWK49_RS22950 e22b57c04fd10df13ae4b4f249b6de2e 61 SUPERFAMILY SSF57802 4 58 3.87E-22 T 06-07-2017 BWK49_RS22950 e22b57c04fd10df13ae4b4f249b6de2e 61 Gene3D G3DSA:2.20.28.10 3 58 7.3E-26 T 06-07-2017 IPR004039 Rubredoxin-type fold BWK49_RS22950 e22b57c04fd10df13ae4b4f249b6de2e 61 Pfam PF00301 Rubredoxin 8 53 5.5E-22 T 06-07-2017 IPR024935 Rubredoxin domain GO:0005506 BWK49_RS22950 e22b57c04fd10df13ae4b4f249b6de2e 61 PIRSF PIRSF000071 1 61 2.1E-22 T 06-07-2017 IPR024922 Rubredoxin GO:0005506|GO:0009055 BWK49_RS22950 e22b57c04fd10df13ae4b4f249b6de2e 61 ProSitePatterns PS00202 Rubredoxin signature. 37 47 - T 06-07-2017 IPR018527 Rubredoxin, iron-binding site GO:0046872 BWK49_RS07060 398795ae576e879dd5645ffec0ca9560 382 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 337 356 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 BWK49_RS07060 398795ae576e879dd5645ffec0ca9560 382 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 119 6.8E-25 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS07060 398795ae576e879dd5645ffec0ca9560 382 Gene3D G3DSA:1.20.140.10 218 377 4.8E-52 T 06-07-2017 BWK49_RS07060 398795ae576e879dd5645ffec0ca9560 382 Gene3D G3DSA:1.10.540.10 1 121 6.9E-31 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS07060 398795ae576e879dd5645ffec0ca9560 382 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 229 376 1.6E-42 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS07060 398795ae576e879dd5645ffec0ca9560 382 Gene3D G3DSA:2.40.110.10 123 217 2.1E-38 T 06-07-2017 BWK49_RS07060 398795ae576e879dd5645ffec0ca9560 382 SUPERFAMILY SSF47203 228 377 4.35E-40 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS07060 398795ae576e879dd5645ffec0ca9560 382 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 217 3.0E-24 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 BWK49_RS07060 398795ae576e879dd5645ffec0ca9560 382 SUPERFAMILY SSF56645 2 237 4.45E-74 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS29020 5370e8a4c73774db373f833422458668 610 SMART SM00382 349 490 4.7E-5 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS29020 5370e8a4c73774db373f833422458668 610 TIGRFAM TIGR03922 T7SS_EccA: type VII secretion AAA-ATPase EccA 41 593 4.7E-205 T 06-07-2017 IPR023835 Type VII secretion system AAA-ATPase, EccA BWK49_RS29020 5370e8a4c73774db373f833422458668 610 Gene3D G3DSA:3.40.50.300 312 502 7.8E-25 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS29020 5370e8a4c73774db373f833422458668 610 SUPERFAMILY SSF52540 313 523 6.87E-28 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS29020 5370e8a4c73774db373f833422458668 610 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 354 486 2.2E-17 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 BWK49_RS29020 5370e8a4c73774db373f833422458668 610 Gene3D G3DSA:1.25.40.10 36 64 6.4E-6 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 BWK49_RS29020 5370e8a4c73774db373f833422458668 610 Gene3D G3DSA:1.25.40.10 113 257 6.4E-6 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 BWK49_RS29020 5370e8a4c73774db373f833422458668 610 SUPERFAMILY SSF48452 172 258 3.8E-6 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 BWK49_RS29020 5370e8a4c73774db373f833422458668 610 SUPERFAMILY SSF48452 118 145 3.8E-6 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 BWK49_RS29020 5370e8a4c73774db373f833422458668 610 PRINTS PR00819 CbxX/CfqX superfamily signature 312 326 9.5E-33 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 BWK49_RS29020 5370e8a4c73774db373f833422458668 610 PRINTS PR00819 CbxX/CfqX superfamily signature 404 423 9.5E-33 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 BWK49_RS29020 5370e8a4c73774db373f833422458668 610 PRINTS PR00819 CbxX/CfqX superfamily signature 475 494 9.5E-33 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 BWK49_RS29020 5370e8a4c73774db373f833422458668 610 PRINTS PR00819 CbxX/CfqX superfamily signature 352 367 9.5E-33 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 BWK49_RS29020 5370e8a4c73774db373f833422458668 610 PRINTS PR00819 CbxX/CfqX superfamily signature 390 404 9.5E-33 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 BWK49_RS29020 5370e8a4c73774db373f833422458668 610 PRINTS PR00819 CbxX/CfqX superfamily signature 458 475 9.5E-33 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 BWK49_RS29020 5370e8a4c73774db373f833422458668 610 PRINTS PR00819 CbxX/CfqX superfamily signature 437 449 9.5E-33 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 BWK49_RS29020 5370e8a4c73774db373f833422458668 610 PRINTS PR00819 CbxX/CfqX superfamily signature 545 557 9.5E-33 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 BWK49_RS03770 f96406256fe88b9f4ff02d8662aaf9bb 145 Pfam PF02136 Nuclear transport factor 2 (NTF2) domain 16 139 2.6E-14 T 06-07-2017 IPR002075 Nuclear transport factor 2 GO:0005622|GO:0006810 BWK49_RS03770 f96406256fe88b9f4ff02d8662aaf9bb 145 SUPERFAMILY SSF54427 15 142 1.18E-21 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS03770 f96406256fe88b9f4ff02d8662aaf9bb 145 Gene3D G3DSA:3.10.450.50 17 139 3.2E-23 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS27970 5f3a9618432854c4bc6b194778611ebb 430 Pfam PF01699 Sodium/calcium exchanger protein 233 372 3.7E-9 T 06-07-2017 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 BWK49_RS27970 5f3a9618432854c4bc6b194778611ebb 430 Pfam PF01699 Sodium/calcium exchanger protein 54 201 1.1E-11 T 06-07-2017 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 BWK49_RS25890 bbe321ced1b624f0ba5fc44de3a9eb36 210 Gene3D G3DSA:3.90.79.10 20 154 4.3E-29 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 BWK49_RS25890 bbe321ced1b624f0ba5fc44de3a9eb36 210 SUPERFAMILY SSF55811 16 154 2.71E-26 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 BWK49_RS25890 bbe321ced1b624f0ba5fc44de3a9eb36 210 ProSitePatterns PS00893 Nudix box signature. 59 80 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 BWK49_RS25890 bbe321ced1b624f0ba5fc44de3a9eb36 210 Pfam PF00293 NUDIX domain 23 142 2.2E-16 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 BWK49_RS25890 bbe321ced1b624f0ba5fc44de3a9eb36 210 PRINTS PR00502 NUDIX hydrolase family signature 68 83 6.4E-5 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 BWK49_RS25890 bbe321ced1b624f0ba5fc44de3a9eb36 210 PRINTS PR00502 NUDIX hydrolase family signature 54 68 6.4E-5 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 BWK49_RS05335 4003a0957509d93729ee76857768ca7e 273 Pfam PF10118 Predicted metal-dependent hydrolase 13 249 5.4E-68 T 06-07-2017 IPR016516 Uncharacterised conserved protein UCP07580 BWK49_RS05335 4003a0957509d93729ee76857768ca7e 273 PIRSF PIRSF007580 1 266 1.7E-62 T 06-07-2017 IPR016516 Uncharacterised conserved protein UCP07580 BWK49_RS05335 4003a0957509d93729ee76857768ca7e 273 Pfam PF11583 P-aminobenzoate N-oxygenase AurF 65 199 1.1E-6 T 06-07-2017 IPR025859 P-aminobenzoate N-oxygenase AurF BWK49_RS15970 9d8efc42e5fb0da5217f37c13f1e2052 263 Pfam PF11139 Sap, sulfolipid-1-addressing protein 5 261 2.4E-63 T 06-07-2017 IPR021315 Glycolipid exporter Gap/Sap BWK49_RS01330 dee2f2422e2c4d9597c9f16674d986a4 153 Pfam PF14232 Domain of unknown function (DUF4334) 94 152 6.5E-29 T 06-07-2017 IPR025568 Domain of unknown function DUF4334 BWK49_RS01330 dee2f2422e2c4d9597c9f16674d986a4 153 Pfam PF14231 GXWXG protein 25 83 9.1E-26 T 06-07-2017 IPR025951 GXWXG domain BWK49_RS03940 2e84d3495774c71b7cb5e6fd80464d12 465 SUPERFAMILY SSF52777 27 171 2.56E-10 T 06-07-2017 BWK49_RS03940 2e84d3495774c71b7cb5e6fd80464d12 465 TIGRFAM TIGR02946 acyl_WS_DGAT: acyltransferase, WS/DGAT/MGAT 1 448 5.5E-118 T 06-07-2017 IPR014292 Acyltransferase, WS/DGAT/MGAT GO:0016746|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 BWK49_RS03940 2e84d3495774c71b7cb5e6fd80464d12 465 Pfam PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain 1 261 1.3E-64 T 06-07-2017 IPR004255 O-acyltransferase, WSD1, N-terminal GO:0004144|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 BWK49_RS03940 2e84d3495774c71b7cb5e6fd80464d12 465 Pfam PF06974 Protein of unknown function (DUF1298) 300 447 5.5E-32 T 06-07-2017 IPR009721 O-acyltransferase WSD1, C-terminal GO:0004144 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 BWK49_RS17765 4ee930726a03c8b81ea1d663fb4b290c 304 SUPERFAMILY SSF52540 1 38 3.68E-14 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS17765 4ee930726a03c8b81ea1d663fb4b290c 304 SUPERFAMILY SSF52540 81 212 3.68E-14 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS18870 b8317d66d138e3afef78cfbb7aeb4a55 521 Gene3D G3DSA:3.40.50.150 283 497 1.1E-63 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS18870 b8317d66d138e3afef78cfbb7aeb4a55 521 SUPERFAMILY SSF53335 233 496 6.69E-64 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS18870 b8317d66d138e3afef78cfbb7aeb4a55 521 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 306 319 - T 06-07-2017 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 BWK49_RS18870 b8317d66d138e3afef78cfbb7aeb4a55 521 Pfam PF01564 Spermine/spermidine synthase 244 459 1.0E-36 T 06-07-2017 BWK49_RS18870 b8317d66d138e3afef78cfbb7aeb4a55 521 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 232 507 23.042 T 06-07-2017 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 BWK49_RS21365 93b934a07e4a03d3d4efa2ec9e385e81 313 SUPERFAMILY SSF51735 10 280 8.59E-60 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS21365 93b934a07e4a03d3d4efa2ec9e385e81 313 Gene3D G3DSA:3.40.50.720 11 246 2.8E-58 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS21365 93b934a07e4a03d3d4efa2ec9e385e81 313 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 89 100 7.2E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS21365 93b934a07e4a03d3d4efa2ec9e385e81 313 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 143 151 7.2E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS21365 93b934a07e4a03d3d4efa2ec9e385e81 313 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 163 182 7.2E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS21365 93b934a07e4a03d3d4efa2ec9e385e81 313 Pfam PF00106 short chain dehydrogenase 15 203 3.1E-47 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS21365 93b934a07e4a03d3d4efa2ec9e385e81 313 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 137 153 1.2E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS21365 93b934a07e4a03d3d4efa2ec9e385e81 313 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 184 201 1.2E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS21365 93b934a07e4a03d3d4efa2ec9e385e81 313 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 89 100 1.2E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS21365 93b934a07e4a03d3d4efa2ec9e385e81 313 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 1.2E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS21365 93b934a07e4a03d3d4efa2ec9e385e81 313 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 182 1.2E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS21365 93b934a07e4a03d3d4efa2ec9e385e81 313 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 150 178 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS01880 aabe114c2b5323ffec95bcedd0c25cb9 593 Gene3D G3DSA:3.50.50.60 357 409 2.2E-54 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS01880 aabe114c2b5323ffec95bcedd0c25cb9 593 Gene3D G3DSA:3.50.50.60 10 267 2.2E-54 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS01880 aabe114c2b5323ffec95bcedd0c25cb9 593 SUPERFAMILY SSF51905 357 409 8.55E-50 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS01880 aabe114c2b5323ffec95bcedd0c25cb9 593 SUPERFAMILY SSF51905 9 251 8.55E-50 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS01880 aabe114c2b5323ffec95bcedd0c25cb9 593 SUPERFAMILY SSF46977 457 568 1.28E-23 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 BWK49_RS01880 aabe114c2b5323ffec95bcedd0c25cb9 593 Pfam PF02910 Fumarate reductase flavoprotein C-term 458 557 9.0E-11 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 BWK49_RS01880 aabe114c2b5323ffec95bcedd0c25cb9 593 SUPERFAMILY SSF56425 234 347 2.27E-14 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 BWK49_RS01880 aabe114c2b5323ffec95bcedd0c25cb9 593 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 163 172 1.3E-7 T 06-07-2017 BWK49_RS01880 aabe114c2b5323ffec95bcedd0c25cb9 593 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 13 35 1.3E-7 T 06-07-2017 BWK49_RS01880 aabe114c2b5323ffec95bcedd0c25cb9 593 PIRSF PIRSF000171 4 562 1.1E-54 T 06-07-2017 IPR030664 Succinate dehydrogenase/fumarate reductase, alpha/adenylylsulphate reductase subunit Reactome: R-HSA-611105|Reactome: R-HSA-71403 BWK49_RS01880 aabe114c2b5323ffec95bcedd0c25cb9 593 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 356 378 5.1E-8 T 06-07-2017 BWK49_RS01880 aabe114c2b5323ffec95bcedd0c25cb9 593 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 14 33 5.1E-8 T 06-07-2017 BWK49_RS01880 aabe114c2b5323ffec95bcedd0c25cb9 593 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 326 342 5.1E-8 T 06-07-2017 BWK49_RS01880 aabe114c2b5323ffec95bcedd0c25cb9 593 Pfam PF00890 FAD binding domain 13 376 3.7E-39 T 06-07-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 BWK49_RS01880 aabe114c2b5323ffec95bcedd0c25cb9 593 Gene3D G3DSA:3.90.700.10 268 346 9.6E-10 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 BWK49_RS01880 aabe114c2b5323ffec95bcedd0c25cb9 593 Gene3D G3DSA:1.20.58.100 440 546 5.0E-17 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 BWK49_RS15455 592fd31eb78f3cbdf3ab273899380355 223 Gene3D G3DSA:1.10.357.10 174 206 1.0E-17 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS15455 592fd31eb78f3cbdf3ab273899380355 223 Gene3D G3DSA:1.10.357.10 11 84 1.0E-17 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS15455 592fd31eb78f3cbdf3ab273899380355 223 SUPERFAMILY SSF46689 11 88 1.46E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS15455 592fd31eb78f3cbdf3ab273899380355 223 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 65 2.9E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS15455 592fd31eb78f3cbdf3ab273899380355 223 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 6.8E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS15455 592fd31eb78f3cbdf3ab273899380355 223 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 6.8E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS17580 f169c1eb0cd548eb0828b42e06c72ff4 1041 Gene3D G3DSA:1.10.730.10 661 832 3.7E-40 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 BWK49_RS17580 f169c1eb0cd548eb0828b42e06c72ff4 1041 Gene3D G3DSA:3.40.50.620 414 650 4.5E-142 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold BWK49_RS17580 f169c1eb0cd548eb0828b42e06c72ff4 1041 Gene3D G3DSA:3.40.50.620 15 203 4.5E-142 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold BWK49_RS17580 f169c1eb0cd548eb0828b42e06c72ff4 1041 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 57 68 - T 06-07-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 BWK49_RS17580 f169c1eb0cd548eb0828b42e06c72ff4 1041 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 538 551 8.7E-32 T 06-07-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 BWK49_RS17580 f169c1eb0cd548eb0828b42e06c72ff4 1041 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 50 61 8.7E-32 T 06-07-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 BWK49_RS17580 f169c1eb0cd548eb0828b42e06c72ff4 1041 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 235 258 8.7E-32 T 06-07-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 BWK49_RS17580 f169c1eb0cd548eb0828b42e06c72ff4 1041 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 578 587 8.7E-32 T 06-07-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 BWK49_RS17580 f169c1eb0cd548eb0828b42e06c72ff4 1041 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 409 424 8.7E-32 T 06-07-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 BWK49_RS17580 f169c1eb0cd548eb0828b42e06c72ff4 1041 Gene3D G3DSA:3.90.740.10 214 389 2.1E-58 T 06-07-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 BWK49_RS17580 f169c1eb0cd548eb0828b42e06c72ff4 1041 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 15 849 5.2E-243 T 06-07-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 BWK49_RS17580 f169c1eb0cd548eb0828b42e06c72ff4 1041 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 23 653 5.2E-180 T 06-07-2017 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 BWK49_RS17580 f169c1eb0cd548eb0828b42e06c72ff4 1041 SUPERFAMILY SSF50677 213 389 3.45E-49 T 06-07-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 BWK49_RS17580 f169c1eb0cd548eb0828b42e06c72ff4 1041 SUPERFAMILY SSF47323 674 898 3.92E-45 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 BWK49_RS17580 f169c1eb0cd548eb0828b42e06c72ff4 1041 Pfam PF08264 Anticodon-binding domain of tRNA 701 838 2.2E-22 T 06-07-2017 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 BWK49_RS17580 f169c1eb0cd548eb0828b42e06c72ff4 1041 Hamap MF_02003 Isoleucine--tRNA ligase [ileS]. 8 1037 13.888 T 06-07-2017 IPR023586 Isoleucine-tRNA ligase, type 2 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 BWK49_RS17580 f169c1eb0cd548eb0828b42e06c72ff4 1041 SUPERFAMILY SSF52374 411 652 2.06E-127 T 06-07-2017 BWK49_RS17580 f169c1eb0cd548eb0828b42e06c72ff4 1041 SUPERFAMILY SSF52374 13 207 2.06E-127 T 06-07-2017 BWK49_RS22725 3d09514e5999e78d219ba6cf137d7a2d 365 Gene3D G3DSA:3.60.120.10 78 363 5.4E-87 T 06-07-2017 IPR005801 ADC synthase GO:0009058 BWK49_RS22725 3d09514e5999e78d219ba6cf137d7a2d 365 Pfam PF00425 chorismate binding enzyme 91 353 8.6E-72 T 06-07-2017 IPR015890 Chorismate-utilising enzyme, C-terminal BWK49_RS22725 3d09514e5999e78d219ba6cf137d7a2d 365 TIGRFAM TIGR00543 isochor_syn: isochorismate synthase 91 361 4.7E-77 T 06-07-2017 IPR004561 Isochorismate synthase GO:0008909|GO:0009058 KEGG: 00130+5.4.4.2|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6406 BWK49_RS22725 3d09514e5999e78d219ba6cf137d7a2d 365 SUPERFAMILY SSF56322 40 362 3.4E-85 T 06-07-2017 IPR005801 ADC synthase GO:0009058 BWK49_RS05975 59463d3db3603b800656636d9dd842d5 413 Pfam PF00534 Glycosyl transferases group 1 190 334 1.6E-21 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 BWK49_RS05975 59463d3db3603b800656636d9dd842d5 413 Pfam PF13439 Glycosyltransferase Family 4 22 180 7.3E-21 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 BWK49_RS05975 59463d3db3603b800656636d9dd842d5 413 SUPERFAMILY SSF53756 19 356 4.49E-57 T 06-07-2017 BWK49_RS05975 59463d3db3603b800656636d9dd842d5 413 Gene3D G3DSA:3.40.50.2000 186 329 2.1E-24 T 06-07-2017 BWK49_RS13680 1523c585c6ff4486cddd9480aa9f7497 262 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 250 3.2E-55 T 06-07-2017 BWK49_RS13680 1523c585c6ff4486cddd9480aa9f7497 262 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 146 174 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS13680 1523c585c6ff4486cddd9480aa9f7497 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 1.6E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS13680 1523c585c6ff4486cddd9480aa9f7497 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 1.6E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS13680 1523c585c6ff4486cddd9480aa9f7497 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 1.6E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS13680 1523c585c6ff4486cddd9480aa9f7497 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 1.6E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS13680 1523c585c6ff4486cddd9480aa9f7497 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 1.6E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS13680 1523c585c6ff4486cddd9480aa9f7497 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 1.6E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS13680 1523c585c6ff4486cddd9480aa9f7497 262 SUPERFAMILY SSF51735 9 250 7.05E-71 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS13680 1523c585c6ff4486cddd9480aa9f7497 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 1.7E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS13680 1523c585c6ff4486cddd9480aa9f7497 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 86 97 1.7E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS13680 1523c585c6ff4486cddd9480aa9f7497 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 1.7E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS13680 1523c585c6ff4486cddd9480aa9f7497 262 Gene3D G3DSA:3.40.50.720 4 250 8.5E-74 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS01185 7ee0d27f4790f28faf1cbbf6ec108b8b 594 Gene3D G3DSA:2.40.110.10 191 286 4.9E-20 T 06-07-2017 BWK49_RS01185 7ee0d27f4790f28faf1cbbf6ec108b8b 594 SUPERFAMILY SSF56645 89 299 1.7E-33 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS01185 7ee0d27f4790f28faf1cbbf6ec108b8b 594 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 309 461 3.1E-41 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS01185 7ee0d27f4790f28faf1cbbf6ec108b8b 594 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 193 290 9.2E-16 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 BWK49_RS01185 7ee0d27f4790f28faf1cbbf6ec108b8b 594 SUPERFAMILY SSF47203 309 461 1.11E-40 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS01185 7ee0d27f4790f28faf1cbbf6ec108b8b 594 Gene3D G3DSA:1.20.140.10 287 461 2.1E-42 T 06-07-2017 BWK49_RS10110 4058d057e6197bd329188f76cf675b30 375 Pfam PF08237 PE-PPE domain 72 316 1.4E-70 T 06-07-2017 IPR013228 PE-PPE, C-terminal BWK49_RS08515 b9dab0a1d695fc23093b393c1b013b42 212 Gene3D G3DSA:1.10.357.10 10 184 1.4E-28 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS08515 b9dab0a1d695fc23093b393c1b013b42 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 1.4E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS08515 b9dab0a1d695fc23093b393c1b013b42 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 1.4E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS08515 b9dab0a1d695fc23093b393c1b013b42 212 SUPERFAMILY SSF46689 9 78 1.13E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS08515 b9dab0a1d695fc23093b393c1b013b42 212 SUPERFAMILY SSF48498 112 174 1.48E-5 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS08515 b9dab0a1d695fc23093b393c1b013b42 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 57 9.7E-15 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS13240 0c3a9e44407a3e7f41ccd40cd1041a5e 432 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 360 369 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 BWK49_RS13240 0c3a9e44407a3e7f41ccd40cd1041a5e 432 Pfam PF00067 Cytochrome P450 213 387 1.1E-21 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS13240 0c3a9e44407a3e7f41ccd40cd1041a5e 432 SUPERFAMILY SSF48264 108 426 3.27E-76 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS13240 0c3a9e44407a3e7f41ccd40cd1041a5e 432 SUPERFAMILY SSF48264 24 73 3.27E-76 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS13240 0c3a9e44407a3e7f41ccd40cd1041a5e 432 Gene3D G3DSA:1.10.630.10 13 428 2.0E-96 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS13240 0c3a9e44407a3e7f41ccd40cd1041a5e 432 PRINTS PR00359 B-class P450 signature 367 378 1.3E-38 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS13240 0c3a9e44407a3e7f41ccd40cd1041a5e 432 PRINTS PR00359 B-class P450 signature 358 367 1.3E-38 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS13240 0c3a9e44407a3e7f41ccd40cd1041a5e 432 PRINTS PR00359 B-class P450 signature 159 175 1.3E-38 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS13240 0c3a9e44407a3e7f41ccd40cd1041a5e 432 PRINTS PR00359 B-class P450 signature 308 335 1.3E-38 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS13240 0c3a9e44407a3e7f41ccd40cd1041a5e 432 PRINTS PR00359 B-class P450 signature 209 231 1.3E-38 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS13240 0c3a9e44407a3e7f41ccd40cd1041a5e 432 PRINTS PR00359 B-class P450 signature 291 302 1.3E-38 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS13240 0c3a9e44407a3e7f41ccd40cd1041a5e 432 PRINTS PR00359 B-class P450 signature 336 351 1.3E-38 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS13240 0c3a9e44407a3e7f41ccd40cd1041a5e 432 PRINTS PR00359 B-class P450 signature 176 191 1.3E-38 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS13240 0c3a9e44407a3e7f41ccd40cd1041a5e 432 PRINTS PR00359 B-class P450 signature 113 124 1.3E-38 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS13240 0c3a9e44407a3e7f41ccd40cd1041a5e 432 PRINTS PR00385 P450 superfamily signature 358 367 2.0E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS13240 0c3a9e44407a3e7f41ccd40cd1041a5e 432 PRINTS PR00385 P450 superfamily signature 367 378 2.0E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS13240 0c3a9e44407a3e7f41ccd40cd1041a5e 432 PRINTS PR00385 P450 superfamily signature 256 273 2.0E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS13240 0c3a9e44407a3e7f41ccd40cd1041a5e 432 PRINTS PR00385 P450 superfamily signature 291 302 2.0E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 SUPERFAMILY SSF47336 1974 2084 4.71E-26 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 SUPERFAMILY SSF50129 1370 1510 4.72E-23 T 06-07-2017 IPR011032 GroES-like BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 Gene3D G3DSA:3.40.47.10 2071 2328 4.9E-88 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 Gene3D G3DSA:3.40.47.10 37 293 1.1E-87 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 SUPERFAMILY SSF55048 683 748 1.29E-11 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 Pfam PF00550 Phosphopantetheine attachment site 4034 4099 1.7E-11 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 Pfam PF00550 Phosphopantetheine attachment site 1980 2046 1.0E-13 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 SUPERFAMILY SSF50129 3422 3563 3.2E-24 T 06-07-2017 IPR011032 GroES-like BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 3554 3575 - T 06-07-2017 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 SMART SM00823 Phosphopantetheine attachment site 1978 2050 2.0E-30 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 SMART SM00823 Phosphopantetheine attachment site 4032 4104 3.2E-30 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 1501 1522 - T 06-07-2017 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 Gene3D G3DSA:3.40.366.10 747 862 2.2E-73 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 Gene3D G3DSA:3.40.366.10 556 679 2.2E-73 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 SMART SM00826 2962 3122 2.3E-80 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 SMART SM00826 928 1092 2.0E-78 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 SMART SM00825 Beta-ketoacyl synthase 37 458 2.6E-213 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 SMART SM00825 Beta-ketoacyl synthase 2071 2493 1.2E-209 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2324 2441 1.0E-42 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 289 406 7.7E-43 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 SMART SM01294 1979 2046 1.3E-6 T 06-07-2017 BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 SMART SM01294 4033 4100 1.3E-5 T 06-07-2017 BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 SUPERFAMILY SSF51735 3246 3400 3.32E-25 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 Pfam PF08659 KR domain 3744 3922 4.9E-57 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 Pfam PF08659 KR domain 1692 1870 3.8E-60 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 Pfam PF13602 Zinc-binding dehydrogenase 3601 3734 1.6E-16 T 06-07-2017 BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 Pfam PF00107 Zinc-binding dehydrogenase 1512 1603 6.6E-17 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 SUPERFAMILY SSF53901 32 398 2.34E-100 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 SUPERFAMILY SSF47336 4025 4113 6.15E-21 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 Gene3D G3DSA:3.40.50.720 1465 1656 1.1E-45 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 Pfam PF00698 Acyl transferase domain 2597 2899 9.3E-58 T 06-07-2017 IPR014043 Acyl transferase BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 Pfam PF00698 Acyl transferase domain 558 882 2.7E-92 T 06-07-2017 IPR014043 Acyl transferase BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 SUPERFAMILY SSF55048 2722 2787 3.79E-12 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 SUPERFAMILY SSF52151 556 685 8.89E-68 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 SUPERFAMILY SSF52151 749 842 8.89E-68 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 SMART SM00829 3426 3735 3.3E-161 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 SMART SM00829 1374 1679 1.6E-162 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2005 2020 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 409 523 2.3E-15 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2444 2561 1.5E-14 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 Gene3D G3DSA:3.40.47.10 294 459 1.5E-64 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 Gene3D G3DSA:3.40.47.10 2329 2493 2.0E-64 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 SUPERFAMILY SSF51735 1473 1650 6.27E-38 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 SUPERFAMILY SSF53901 2065 2433 2.44E-98 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 194 210 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 Gene3D G3DSA:3.90.180.10 3422 3558 1.2E-38 T 06-07-2017 IPR011032 GroES-like BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 1394 1448 1.7E-4 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 SUPERFAMILY SSF52151 2788 2887 1.36E-72 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 SUPERFAMILY SSF52151 2595 2723 1.36E-72 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 560 863 7.0E-119 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2599 2897 2.4E-115 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 Gene3D G3DSA:3.40.366.10 2787 2898 1.7E-75 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 Gene3D G3DSA:3.40.366.10 2589 2717 1.7E-75 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 Gene3D G3DSA:3.90.180.10 1377 1451 3.7E-10 T 06-07-2017 IPR011032 GroES-like BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 Gene3D G3DSA:3.40.50.720 3559 3657 2.2E-17 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 SUPERFAMILY SSF51735 3526 3706 6.36E-33 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 SUPERFAMILY SSF51735 1689 1950 9.12E-44 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 Gene3D G3DSA:1.10.1200.10 1976 2052 1.1E-24 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 Gene3D G3DSA:1.10.1200.10 4030 4104 1.1E-22 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 Pfam PF14765 Polyketide synthase dehydratase 928 1205 5.8E-52 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 Pfam PF14765 Polyketide synthase dehydratase 2962 3236 2.1E-52 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 Gene3D G3DSA:3.30.70.250 682 739 3.6E-5 T 06-07-2017 BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 Gene3D G3DSA:3.30.70.250 2722 2786 5.6E-10 T 06-07-2017 BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 SUPERFAMILY SSF51735 3741 3981 8.89E-43 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2069 2316 5.7E-88 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 35 281 1.7E-87 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 Gene3D G3DSA:3.40.50.720 3744 3942 3.5E-35 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 Gene3D G3DSA:3.40.50.720 1690 1898 2.3E-36 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 ProSitePatterns PS00012 Phosphopantetheine attachment site. 4059 4074 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3744 3924 1.2E-59 T 06-07-2017 BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1692 1872 3.1E-57 T 06-07-2017 BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 2229 2245 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site BWK49_RS13610 9e6592dc42e7fb7849a51c722408016f 4184 SUPERFAMILY SSF51735 1142 1349 4.72E-20 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS04505 a7357b2042f6bb77981844a631d5695c 518 SUPERFAMILY SSF56112 80 307 2.6E-54 T 06-07-2017 IPR011009 Protein kinase-like domain BWK49_RS04505 a7357b2042f6bb77981844a631d5695c 518 Gene3D G3DSA:1.10.510.10 187 358 4.4E-29 T 06-07-2017 BWK49_RS04505 a7357b2042f6bb77981844a631d5695c 518 Pfam PF00069 Protein kinase domain 80 283 3.2E-40 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 BWK49_RS04505 a7357b2042f6bb77981844a631d5695c 518 SMART SM00220 77 325 1.5E-33 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 BWK49_RS04505 a7357b2042f6bb77981844a631d5695c 518 Gene3D G3DSA:3.30.200.20 57 186 4.8E-29 T 06-07-2017 BWK49_RS04505 a7357b2042f6bb77981844a631d5695c 518 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 83 106 - T 06-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 BWK49_RS05320 4f2dcbfb9ea3368a0c54ee5dba937ea0 525 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 187 212 1.1E-5 T 06-07-2017 BWK49_RS05320 4f2dcbfb9ea3368a0c54ee5dba937ea0 525 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 146 155 1.1E-5 T 06-07-2017 BWK49_RS05320 4f2dcbfb9ea3368a0c54ee5dba937ea0 525 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 21 43 1.1E-5 T 06-07-2017 BWK49_RS05320 4f2dcbfb9ea3368a0c54ee5dba937ea0 525 SUPERFAMILY SSF51905 22 241 3.35E-51 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS05320 4f2dcbfb9ea3368a0c54ee5dba937ea0 525 SUPERFAMILY SSF51905 312 434 3.35E-51 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS05320 4f2dcbfb9ea3368a0c54ee5dba937ea0 525 Gene3D G3DSA:3.50.50.60 399 507 1.8E-62 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS05320 4f2dcbfb9ea3368a0c54ee5dba937ea0 525 Gene3D G3DSA:3.50.50.60 12 191 1.8E-62 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS05320 4f2dcbfb9ea3368a0c54ee5dba937ea0 525 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 21 240 1.8E-14 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS05320 4f2dcbfb9ea3368a0c54ee5dba937ea0 525 Gene3D G3DSA:3.50.50.60 302 356 8.2E-9 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS05320 4f2dcbfb9ea3368a0c54ee5dba937ea0 525 Gene3D G3DSA:3.50.50.60 192 220 8.2E-9 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS19960 cb994d442f381170602ddf1477b5ecca 463 SUPERFAMILY SSF52317 249 453 1.39E-28 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like BWK49_RS19960 cb994d442f381170602ddf1477b5ecca 463 Gene3D G3DSA:3.40.50.880 250 459 2.4E-26 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like BWK49_RS19960 cb994d442f381170602ddf1477b5ecca 463 Gene3D G3DSA:3.40.50.300 2 39 1.4E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS19960 cb994d442f381170602ddf1477b5ecca 463 Gene3D G3DSA:3.40.50.300 47 192 2.9E-17 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS19960 cb994d442f381170602ddf1477b5ecca 463 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 2 178 1.2E-25 T 06-07-2017 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain BWK49_RS19960 cb994d442f381170602ddf1477b5ecca 463 Hamap MF_00027 Cobyrinate a,c-diamide synthase [cbiA]. 1 445 39.971 T 06-07-2017 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 BWK49_RS19960 cb994d442f381170602ddf1477b5ecca 463 SUPERFAMILY SSF52540 2 194 8.68E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS19960 cb994d442f381170602ddf1477b5ecca 463 TIGRFAM TIGR00379 cobB: cobyrinic acid a,c-diamide synthase 2 455 6.6E-111 T 06-07-2017 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 BWK49_RS19960 cb994d442f381170602ddf1477b5ecca 463 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 250 440 4.1E-22 T 06-07-2017 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 BWK49_RS20835 a8bf156191569d836f6fe137a879cfaa 381 SUPERFAMILY SSF52440 18 158 3.26E-36 T 06-07-2017 IPR016185 Pre-ATP-grasp domain BWK49_RS20835 a8bf156191569d836f6fe137a879cfaa 381 Pfam PF01820 D-ala D-ala ligase N-terminus 20 149 1.6E-34 T 06-07-2017 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 BWK49_RS20835 a8bf156191569d836f6fe137a879cfaa 381 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 126 137 - T 06-07-2017 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 BWK49_RS20835 a8bf156191569d836f6fe137a879cfaa 381 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 19 374 41.241 T 06-07-2017 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 BWK49_RS20835 a8bf156191569d836f6fe137a879cfaa 381 PIRSF PIRSF039102 16 378 8.6E-108 T 06-07-2017 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 BWK49_RS20835 a8bf156191569d836f6fe137a879cfaa 381 Pfam PF07478 D-ala D-ala ligase C-terminus 166 371 1.3E-71 T 06-07-2017 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 BWK49_RS20835 a8bf156191569d836f6fe137a879cfaa 381 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 317 344 - T 06-07-2017 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 BWK49_RS20835 a8bf156191569d836f6fe137a879cfaa 381 Gene3D G3DSA:3.30.470.20 243 375 1.2E-46 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 BWK49_RS20835 a8bf156191569d836f6fe137a879cfaa 381 Gene3D G3DSA:3.30.470.20 150 175 1.2E-46 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 BWK49_RS20835 a8bf156191569d836f6fe137a879cfaa 381 Gene3D G3DSA:3.40.50.20 18 148 1.3E-37 T 06-07-2017 IPR016185 Pre-ATP-grasp domain BWK49_RS20835 a8bf156191569d836f6fe137a879cfaa 381 Gene3D G3DSA:3.30.1490.20 190 239 1.1E-21 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 BWK49_RS20835 a8bf156191569d836f6fe137a879cfaa 381 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 20 373 1.4E-113 T 06-07-2017 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 BWK49_RS20835 a8bf156191569d836f6fe137a879cfaa 381 SUPERFAMILY SSF56059 159 374 3.21E-54 T 06-07-2017 BWK49_RS11200 b08d15aad152f0f3eba5e6cfb0b9cb15 931 SUPERFAMILY SSF53732 4 401 5.89E-219 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 BWK49_RS11200 b08d15aad152f0f3eba5e6cfb0b9cb15 931 SUPERFAMILY SSF53732 438 665 5.89E-219 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 BWK49_RS11200 b08d15aad152f0f3eba5e6cfb0b9cb15 931 Gene3D G3DSA:3.40.1060.10 245 362 2.8E-36 T 06-07-2017 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 BWK49_RS11200 b08d15aad152f0f3eba5e6cfb0b9cb15 931 Pfam PF00330 Aconitase family (aconitate hydratase) 69 600 3.9E-177 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 BWK49_RS11200 b08d15aad152f0f3eba5e6cfb0b9cb15 931 PRINTS PR00415 Aconitase family signature 198 211 8.9E-43 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 BWK49_RS11200 b08d15aad152f0f3eba5e6cfb0b9cb15 931 PRINTS PR00415 Aconitase family signature 274 287 8.9E-43 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 BWK49_RS11200 b08d15aad152f0f3eba5e6cfb0b9cb15 931 PRINTS PR00415 Aconitase family signature 469 480 8.9E-43 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 BWK49_RS11200 b08d15aad152f0f3eba5e6cfb0b9cb15 931 PRINTS PR00415 Aconitase family signature 288 301 8.9E-43 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 BWK49_RS11200 b08d15aad152f0f3eba5e6cfb0b9cb15 931 PRINTS PR00415 Aconitase family signature 531 544 8.9E-43 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 BWK49_RS11200 b08d15aad152f0f3eba5e6cfb0b9cb15 931 PRINTS PR00415 Aconitase family signature 141 154 8.9E-43 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 BWK49_RS11200 b08d15aad152f0f3eba5e6cfb0b9cb15 931 PRINTS PR00415 Aconitase family signature 367 381 8.9E-43 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 BWK49_RS11200 b08d15aad152f0f3eba5e6cfb0b9cb15 931 PRINTS PR00415 Aconitase family signature 212 227 8.9E-43 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 BWK49_RS11200 b08d15aad152f0f3eba5e6cfb0b9cb15 931 PRINTS PR00415 Aconitase family signature 165 173 8.9E-43 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 BWK49_RS11200 b08d15aad152f0f3eba5e6cfb0b9cb15 931 Gene3D G3DSA:3.30.499.10 30 244 4.7E-76 T 06-07-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 BWK49_RS11200 b08d15aad152f0f3eba5e6cfb0b9cb15 931 ProSitePatterns PS00450 Aconitase family signature 1. 465 481 - T 06-07-2017 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 BWK49_RS11200 b08d15aad152f0f3eba5e6cfb0b9cb15 931 SUPERFAMILY SSF52016 669 928 2.75E-83 T 06-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel BWK49_RS11200 b08d15aad152f0f3eba5e6cfb0b9cb15 931 Gene3D G3DSA:3.20.19.10 675 927 2.2E-73 T 06-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel BWK49_RS11200 b08d15aad152f0f3eba5e6cfb0b9cb15 931 Gene3D G3DSA:3.30.499.10 457 613 3.6E-63 T 06-07-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 BWK49_RS11200 b08d15aad152f0f3eba5e6cfb0b9cb15 931 Gene3D G3DSA:3.30.499.10 364 388 3.6E-63 T 06-07-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 BWK49_RS11200 b08d15aad152f0f3eba5e6cfb0b9cb15 931 Pfam PF00694 Aconitase C-terminal domain 730 859 3.5E-41 T 06-07-2017 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 BWK49_RS11200 b08d15aad152f0f3eba5e6cfb0b9cb15 931 ProSitePatterns PS01244 Aconitase family signature 2. 531 544 - T 06-07-2017 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 BWK49_RS21845 e176fcf4acaeeddcacb33776eedff3da 370 TIGRFAM TIGR00020 prfB: peptide chain release factor 2 3 365 1.8E-168 T 06-07-2017 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 BWK49_RS21845 e176fcf4acaeeddcacb33776eedff3da 370 Gene3D G3DSA:3.30.160.20 229 305 1.1E-32 T 06-07-2017 IPR014720 Double-stranded RNA-binding domain BWK49_RS21845 e176fcf4acaeeddcacb33776eedff3da 370 Gene3D G3DSA:1.20.58.410 3 116 2.9E-33 T 06-07-2017 BWK49_RS21845 e176fcf4acaeeddcacb33776eedff3da 370 Pfam PF03462 PCRF domain 29 220 6.4E-56 T 06-07-2017 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 BWK49_RS21845 e176fcf4acaeeddcacb33776eedff3da 370 SMART SM00937 83 195 1.2E-46 T 06-07-2017 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 BWK49_RS21845 e176fcf4acaeeddcacb33776eedff3da 370 Hamap MF_00094 Peptide chain release factor 2 [prfB]. 1 365 38.72 T 06-07-2017 IPR020853 Peptide chain release factor 2, bacterial GO:0005737|GO:0006415|GO:0016149 BWK49_RS21845 e176fcf4acaeeddcacb33776eedff3da 370 Pfam PF00472 RF-1 domain 230 337 5.4E-36 T 06-07-2017 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 BWK49_RS21845 e176fcf4acaeeddcacb33776eedff3da 370 SUPERFAMILY SSF75620 28 366 8.11E-120 T 06-07-2017 BWK49_RS21845 e176fcf4acaeeddcacb33776eedff3da 370 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 245 261 - T 06-07-2017 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 BWK49_RS10880 f0a56536e33265b29a3d357b17912a09 254 SUPERFAMILY SSF51735 12 251 3.45E-56 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS10880 f0a56536e33265b29a3d357b17912a09 254 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 249 2.6E-44 T 06-07-2017 BWK49_RS10880 f0a56536e33265b29a3d357b17912a09 254 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS10880 f0a56536e33265b29a3d357b17912a09 254 Gene3D G3DSA:3.40.50.720 12 251 9.4E-58 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS10880 f0a56536e33265b29a3d357b17912a09 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 2.9E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS10880 f0a56536e33265b29a3d357b17912a09 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 2.9E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS10880 f0a56536e33265b29a3d357b17912a09 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 2.9E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS10880 f0a56536e33265b29a3d357b17912a09 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 2.9E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS10880 f0a56536e33265b29a3d357b17912a09 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 2.9E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS10880 f0a56536e33265b29a3d357b17912a09 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 3.2E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS10880 f0a56536e33265b29a3d357b17912a09 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 3.2E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS10880 f0a56536e33265b29a3d357b17912a09 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 3.2E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS19460 cdea4f726b68de969982b9c33fd75a04 329 Pfam PF00140 Sigma-70 factor, region 1.2 31 64 7.1E-12 T 06-07-2017 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS19460 cdea4f726b68de969982b9c33fd75a04 329 Gene3D G3DSA:1.10.10.10 169 220 3.5E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS19460 cdea4f726b68de969982b9c33fd75a04 329 SUPERFAMILY SSF88946 30 166 1.15E-50 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS19460 cdea4f726b68de969982b9c33fd75a04 329 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 120 133 - T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS19460 cdea4f726b68de969982b9c33fd75a04 329 Pfam PF04539 Sigma-70 region 3 175 251 1.8E-25 T 06-07-2017 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS19460 cdea4f726b68de969982b9c33fd75a04 329 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 289 315 - T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS19460 cdea4f726b68de969982b9c33fd75a04 329 Pfam PF04545 Sigma-70, region 4 264 317 5.3E-19 T 06-07-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS19460 cdea4f726b68de969982b9c33fd75a04 329 SUPERFAMILY SSF88659 169 242 2.49E-18 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS19460 cdea4f726b68de969982b9c33fd75a04 329 Gene3D G3DSA:1.10.10.10 260 328 1.5E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS19460 cdea4f726b68de969982b9c33fd75a04 329 Pfam PF04542 Sigma-70 region 2 96 165 7.5E-22 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS19460 cdea4f726b68de969982b9c33fd75a04 329 SUPERFAMILY SSF88659 226 324 1.4E-25 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS19460 cdea4f726b68de969982b9c33fd75a04 329 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 92 317 3.7E-37 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS19460 cdea4f726b68de969982b9c33fd75a04 329 Gene3D G3DSA:1.10.601.10 11 165 5.0E-62 T 06-07-2017 BWK49_RS19460 cdea4f726b68de969982b9c33fd75a04 329 PRINTS PR00046 Major sigma-70 factor signature 144 152 1.3E-27 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS19460 cdea4f726b68de969982b9c33fd75a04 329 PRINTS PR00046 Major sigma-70 factor signature 289 304 1.3E-27 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS19460 cdea4f726b68de969982b9c33fd75a04 329 PRINTS PR00046 Major sigma-70 factor signature 120 133 1.3E-27 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS19460 cdea4f726b68de969982b9c33fd75a04 329 PRINTS PR00046 Major sigma-70 factor signature 268 280 1.3E-27 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS19460 cdea4f726b68de969982b9c33fd75a04 329 PRINTS PR00046 Major sigma-70 factor signature 304 315 1.3E-27 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS09990 ebe5709338bc4b1cef13726814d14e2a 103 Pfam PF00829 Ribosomal prokaryotic L21 protein 4 102 7.6E-34 T 06-07-2017 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS09990 ebe5709338bc4b1cef13726814d14e2a 103 ProSitePatterns PS01169 Ribosomal protein L21 signature. 73 95 - T 06-07-2017 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS09990 ebe5709338bc4b1cef13726814d14e2a 103 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 3 103 19.846 T 06-07-2017 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS09990 ebe5709338bc4b1cef13726814d14e2a 103 TIGRFAM TIGR00061 L21: ribosomal protein bL21 4 102 1.3E-25 T 06-07-2017 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS09990 ebe5709338bc4b1cef13726814d14e2a 103 SUPERFAMILY SSF141091 4 102 8.89E-32 T 06-07-2017 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS23565 05f0ca9e5e5109cfdea501edf0516326 783 Pfam PF00498 FHA domain 150 212 9.8E-15 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 BWK49_RS23565 05f0ca9e5e5109cfdea501edf0516326 783 Pfam PF00498 FHA domain 27 89 1.4E-8 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 BWK49_RS23565 05f0ca9e5e5109cfdea501edf0516326 783 Gene3D G3DSA:2.60.200.20 12 90 1.8E-11 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 BWK49_RS23565 05f0ca9e5e5109cfdea501edf0516326 783 SUPERFAMILY SSF49879 23 105 3.25E-15 T 06-07-2017 IPR008984 SMAD/FHA domain GO:0005515 BWK49_RS23565 05f0ca9e5e5109cfdea501edf0516326 783 Gene3D G3DSA:2.60.200.20 138 219 1.9E-19 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 BWK49_RS23565 05f0ca9e5e5109cfdea501edf0516326 783 Gene3D G3DSA:3.40.50.300 228 455 8.2E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS23565 05f0ca9e5e5109cfdea501edf0516326 783 SUPERFAMILY SSF49879 120 219 1.68E-23 T 06-07-2017 IPR008984 SMAD/FHA domain GO:0005515 BWK49_RS23565 05f0ca9e5e5109cfdea501edf0516326 783 ProSitePatterns PS00211 ABC transporters family signature. 370 384 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 BWK49_RS23565 05f0ca9e5e5109cfdea501edf0516326 783 SMART SM00240 148 198 1.7E-10 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 BWK49_RS23565 05f0ca9e5e5109cfdea501edf0516326 783 SMART SM00240 25 75 2.1E-4 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 BWK49_RS23565 05f0ca9e5e5109cfdea501edf0516326 783 SUPERFAMILY SSF52540 236 456 1.81E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS23565 05f0ca9e5e5109cfdea501edf0516326 783 Pfam PF00005 ABC transporter 251 398 3.5E-32 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 BWK49_RS23565 05f0ca9e5e5109cfdea501edf0516326 783 SMART SM00382 260 493 1.8E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS23565 05f0ca9e5e5109cfdea501edf0516326 783 Pfam PF01061 ABC-2 type transporter 512 726 7.4E-19 T 06-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 BWK49_RS14115 c38671978b0ea240bc8608e00304c9c9 395 SMART SM00331 174 392 3.8E-4 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 BWK49_RS14115 c38671978b0ea240bc8608e00304c9c9 395 SMART SM00448 15 128 2.0E-14 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 BWK49_RS14115 c38671978b0ea240bc8608e00304c9c9 395 SUPERFAMILY SSF52172 14 140 1.24E-27 T 06-07-2017 IPR011006 CheY-like superfamily BWK49_RS14115 c38671978b0ea240bc8608e00304c9c9 395 Gene3D G3DSA:3.40.50.2300 15 139 3.3E-28 T 06-07-2017 BWK49_RS14115 c38671978b0ea240bc8608e00304c9c9 395 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 200 392 2.8E-23 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 BWK49_RS14115 c38671978b0ea240bc8608e00304c9c9 395 Pfam PF00072 Response regulator receiver domain 17 126 2.9E-18 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 BWK49_RS16405 e4c3df7e1fde841b2c1dd3f40594988b 431 Gene3D G3DSA:3.40.109.10 227 429 4.1E-19 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 BWK49_RS16405 e4c3df7e1fde841b2c1dd3f40594988b 431 TIGRFAM TIGR03605 antibiot_sagB: SagB-type dehydrogenase domain 255 426 1.8E-42 T 06-07-2017 IPR020051 SagB-type dehydrogenase domain BWK49_RS16405 e4c3df7e1fde841b2c1dd3f40594988b 431 SUPERFAMILY SSF55469 236 299 1.05E-17 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 BWK49_RS16405 e4c3df7e1fde841b2c1dd3f40594988b 431 SUPERFAMILY SSF55469 327 430 1.05E-17 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 BWK49_RS16405 e4c3df7e1fde841b2c1dd3f40594988b 431 Pfam PF00881 Nitroreductase family 239 426 1.8E-18 T 06-07-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 BWK49_RS22785 a22eca8d84eb504a334cc5a710443811 336 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 24 88 5.3E-16 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 BWK49_RS22785 a22eca8d84eb504a334cc5a710443811 336 SUPERFAMILY SSF50129 1 160 1.98E-33 T 06-07-2017 IPR011032 GroES-like BWK49_RS22785 a22eca8d84eb504a334cc5a710443811 336 Gene3D G3DSA:3.40.50.720 153 282 9.6E-37 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS22785 a22eca8d84eb504a334cc5a710443811 336 SUPERFAMILY SSF51735 128 298 1.37E-36 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS22785 a22eca8d84eb504a334cc5a710443811 336 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 06-07-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 BWK49_RS22785 a22eca8d84eb504a334cc5a710443811 336 Gene3D G3DSA:3.90.180.10 1 152 1.6E-30 T 06-07-2017 IPR011032 GroES-like BWK49_RS22785 a22eca8d84eb504a334cc5a710443811 336 Pfam PF00107 Zinc-binding dehydrogenase 161 291 5.2E-23 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 BWK49_RS15405 4604e1ed61b59128b1161c18d852668a 558 Gene3D G3DSA:3.90.700.10 341 491 1.7E-33 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 BWK49_RS15405 4604e1ed61b59128b1161c18d852668a 558 SUPERFAMILY SSF51905 216 327 6.81E-35 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS15405 4604e1ed61b59128b1161c18d852668a 558 SUPERFAMILY SSF51905 3 124 6.81E-35 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS15405 4604e1ed61b59128b1161c18d852668a 558 SUPERFAMILY SSF51905 499 557 6.81E-35 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS15405 4604e1ed61b59128b1161c18d852668a 558 Gene3D G3DSA:3.50.50.60 207 318 3.5E-59 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS15405 4604e1ed61b59128b1161c18d852668a 558 Gene3D G3DSA:3.50.50.60 496 557 3.5E-59 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS15405 4604e1ed61b59128b1161c18d852668a 558 Gene3D G3DSA:3.50.50.60 4 144 3.5E-59 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS15405 4604e1ed61b59128b1161c18d852668a 558 Pfam PF00890 FAD binding domain 10 541 1.5E-80 T 06-07-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 BWK49_RS15405 4604e1ed61b59128b1161c18d852668a 558 SUPERFAMILY SSF56425 319 492 1.75E-35 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 BWK49_RS08800 6eccf273f700f6e6dd6a5e0fa2d5ccac 146 Pfam PF03061 Thioesterase superfamily 60 137 2.5E-13 T 06-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 BWK49_RS08800 6eccf273f700f6e6dd6a5e0fa2d5ccac 146 Gene3D G3DSA:3.10.129.10 18 145 2.5E-32 T 06-07-2017 IPR029069 HotDog domain BWK49_RS08800 6eccf273f700f6e6dd6a5e0fa2d5ccac 146 SUPERFAMILY SSF54637 16 144 1.45E-30 T 06-07-2017 IPR029069 HotDog domain BWK49_RS08800 6eccf273f700f6e6dd6a5e0fa2d5ccac 146 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 28 143 1.1E-20 T 06-07-2017 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-75105 BWK49_RS18090 f76a3f3e6b20309c485740c3a0096a90 196 SUPERFAMILY SSF55729 15 173 3.21E-32 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase BWK49_RS18090 f76a3f3e6b20309c485740c3a0096a90 196 Gene3D G3DSA:3.40.630.30 15 186 3.3E-39 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase BWK49_RS18090 f76a3f3e6b20309c485740c3a0096a90 196 Pfam PF13302 Acetyltransferase (GNAT) domain 20 164 2.3E-24 T 06-07-2017 IPR000182 GNAT domain GO:0008080 BWK49_RS22230 cdc464e6a6537058665530e6c872922b 352 Gene3D G3DSA:3.90.15.10 89 215 3.4E-34 T 06-07-2017 IPR014711 DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type GO:0003677|GO:0003917|GO:0006265 BWK49_RS22230 cdc464e6a6537058665530e6c872922b 352 SUPERFAMILY SSF55869 23 83 1.44E-20 T 06-07-2017 BWK49_RS22230 cdc464e6a6537058665530e6c872922b 352 PRINTS PR00416 Eukaryotic DNA topoisomerase I signature 146 160 1.1E-10 T 06-07-2017 IPR001631 DNA topoisomerase I GO:0003677|GO:0003917|GO:0006265 BWK49_RS22230 cdc464e6a6537058665530e6c872922b 352 PRINTS PR00416 Eukaryotic DNA topoisomerase I signature 233 247 1.1E-10 T 06-07-2017 IPR001631 DNA topoisomerase I GO:0003677|GO:0003917|GO:0006265 BWK49_RS22230 cdc464e6a6537058665530e6c872922b 352 PRINTS PR00416 Eukaryotic DNA topoisomerase I signature 167 183 1.1E-10 T 06-07-2017 IPR001631 DNA topoisomerase I GO:0003677|GO:0003917|GO:0006265 BWK49_RS22230 cdc464e6a6537058665530e6c872922b 352 PRINTS PR00416 Eukaryotic DNA topoisomerase I signature 284 295 1.1E-10 T 06-07-2017 IPR001631 DNA topoisomerase I GO:0003677|GO:0003917|GO:0006265 BWK49_RS22230 cdc464e6a6537058665530e6c872922b 352 PRINTS PR00416 Eukaryotic DNA topoisomerase I signature 123 142 1.1E-10 T 06-07-2017 IPR001631 DNA topoisomerase I GO:0003677|GO:0003917|GO:0006265 BWK49_RS22230 cdc464e6a6537058665530e6c872922b 352 SUPERFAMILY SSF56349 79 314 1.32E-59 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 BWK49_RS22230 cdc464e6a6537058665530e6c872922b 352 Pfam PF01028 Eukaryotic DNA topoisomerase I, catalytic core 81 286 3.4E-26 T 06-07-2017 IPR013500 DNA topoisomerase I, catalytic core, eukaryotic-type GO:0003677|GO:0003918|GO:0006265 BWK49_RS22230 cdc464e6a6537058665530e6c872922b 352 Gene3D G3DSA:1.20.120.380 234 314 5.4E-24 T 06-07-2017 IPR027362 DNA topoisomerase I catalytic fragment, domain 2 BWK49_RS04025 09457ee93d0b91fd784467acef16686e 204 SUPERFAMILY SSF48498 81 195 4.89E-17 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS04025 09457ee93d0b91fd784467acef16686e 204 Pfam PF16859 Bacterial transcriptional repressor C-terminal 78 178 2.8E-20 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS04025 09457ee93d0b91fd784467acef16686e 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 64 8.6E-15 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS04025 09457ee93d0b91fd784467acef16686e 204 Gene3D G3DSA:1.10.357.10 57 200 4.9E-28 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS04025 09457ee93d0b91fd784467acef16686e 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 1.0E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS04025 09457ee93d0b91fd784467acef16686e 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 1.0E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS04025 09457ee93d0b91fd784467acef16686e 204 SUPERFAMILY SSF46689 8 69 3.78E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS04025 09457ee93d0b91fd784467acef16686e 204 Gene3D G3DSA:1.10.10.60 8 56 2.5E-22 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS06755 e0427f2d059b84e98fe9749ada883373 795 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 299 305 - T 06-07-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 BWK49_RS06755 e0427f2d059b84e98fe9749ada883373 795 SUPERFAMILY SSF81653 102 193 3.01E-19 T 06-07-2017 BWK49_RS06755 e0427f2d059b84e98fe9749ada883373 795 SUPERFAMILY SSF56784 378 393 5.13E-37 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS06755 e0427f2d059b84e98fe9749ada883373 795 SUPERFAMILY SSF56784 432 576 5.13E-37 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS06755 e0427f2d059b84e98fe9749ada883373 795 SUPERFAMILY SSF56784 284 309 5.13E-37 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS06755 e0427f2d059b84e98fe9749ada883373 795 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 507 609 2.2E-25 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 BWK49_RS06755 e0427f2d059b84e98fe9749ada883373 795 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 71 327 2.5E-30 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 BWK49_RS06755 e0427f2d059b84e98fe9749ada883373 795 Pfam PF00122 E1-E2 ATPase 67 288 2.9E-51 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 BWK49_RS06755 e0427f2d059b84e98fe9749ada883373 795 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 297 311 3.2E-24 T 06-07-2017 BWK49_RS06755 e0427f2d059b84e98fe9749ada883373 795 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 555 567 3.2E-24 T 06-07-2017 BWK49_RS06755 e0427f2d059b84e98fe9749ada883373 795 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 532 551 3.2E-24 T 06-07-2017 BWK49_RS06755 e0427f2d059b84e98fe9749ada883373 795 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 146 160 3.2E-24 T 06-07-2017 BWK49_RS06755 e0427f2d059b84e98fe9749ada883373 795 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 456 466 3.2E-24 T 06-07-2017 BWK49_RS06755 e0427f2d059b84e98fe9749ada883373 795 SUPERFAMILY SSF81665 581 786 1.44E-60 T 06-07-2017 BWK49_RS06755 e0427f2d059b84e98fe9749ada883373 795 SUPERFAMILY SSF81665 197 291 1.44E-60 T 06-07-2017 BWK49_RS06755 e0427f2d059b84e98fe9749ada883373 795 SUPERFAMILY SSF81665 3 99 1.44E-60 T 06-07-2017 BWK49_RS06755 e0427f2d059b84e98fe9749ada883373 795 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 532 548 3.6E-5 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 BWK49_RS06755 e0427f2d059b84e98fe9749ada883373 795 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 397 415 3.6E-5 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 BWK49_RS06755 e0427f2d059b84e98fe9749ada883373 795 Pfam PF00702 haloacid dehalogenase-like hydrolase 293 546 3.2E-21 T 06-07-2017 BWK49_RS06755 e0427f2d059b84e98fe9749ada883373 795 Gene3D G3DSA:1.20.1110.10 66 93 5.9E-48 T 06-07-2017 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 BWK49_RS06755 e0427f2d059b84e98fe9749ada883373 795 Gene3D G3DSA:1.20.1110.10 501 780 5.9E-48 T 06-07-2017 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 BWK49_RS06755 e0427f2d059b84e98fe9749ada883373 795 Gene3D G3DSA:3.40.1110.10 287 314 1.4E-5 T 06-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 BWK49_RS06755 e0427f2d059b84e98fe9749ada883373 795 SUPERFAMILY SSF81660 303 445 6.7E-6 T 06-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 BWK49_RS06755 e0427f2d059b84e98fe9749ada883373 795 Gene3D G3DSA:2.70.150.10 94 194 2.5E-22 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 BWK49_RS06755 e0427f2d059b84e98fe9749ada883373 795 Gene3D G3DSA:2.70.150.10 2 42 2.5E-22 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 BWK49_RS07055 01c23e0a40fd7f749a82337dbbc4faaa 531 Pfam PF01039 Carboxyl transferase domain 48 520 1.2E-141 T 06-07-2017 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 BWK49_RS07055 01c23e0a40fd7f749a82337dbbc4faaa 531 SUPERFAMILY SSF52096 24 266 1.96E-64 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS07055 01c23e0a40fd7f749a82337dbbc4faaa 531 SUPERFAMILY SSF52096 232 512 1.57E-74 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS07055 01c23e0a40fd7f749a82337dbbc4faaa 531 Gene3D G3DSA:3.90.226.10 275 523 2.0E-73 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS07055 01c23e0a40fd7f749a82337dbbc4faaa 531 Gene3D G3DSA:3.90.226.10 29 267 5.1E-65 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS07500 0510f8a7e10a86ea66b1b6ff9bd967ab 1223 Pfam PF00271 Helicase conserved C-terminal domain 855 956 1.8E-15 T 06-07-2017 IPR001650 Helicase, C-terminal BWK49_RS07500 0510f8a7e10a86ea66b1b6ff9bd967ab 1223 SUPERFAMILY SSF143517 1048 1201 6.02E-31 T 06-07-2017 BWK49_RS07500 0510f8a7e10a86ea66b1b6ff9bd967ab 1223 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 57 1196 28.386 T 06-07-2017 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 BWK49_RS07500 0510f8a7e10a86ea66b1b6ff9bd967ab 1223 Pfam PF03461 TRCF domain 1058 1135 3.5E-23 T 06-07-2017 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 BWK49_RS07500 0510f8a7e10a86ea66b1b6ff9bd967ab 1223 SUPERFAMILY SSF52540 572 830 2.08E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS07500 0510f8a7e10a86ea66b1b6ff9bd967ab 1223 Pfam PF02559 CarD-like/TRCF domain 523 622 7.7E-29 T 06-07-2017 IPR003711 CarD-like/TRCF domain BWK49_RS07500 0510f8a7e10a86ea66b1b6ff9bd967ab 1223 SMART SM00982 1057 1156 2.1E-39 T 06-07-2017 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 BWK49_RS07500 0510f8a7e10a86ea66b1b6ff9bd967ab 1223 Gene3D G3DSA:3.40.50.300 832 1010 2.7E-33 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS07500 0510f8a7e10a86ea66b1b6ff9bd967ab 1223 Pfam PF00270 DEAD/DEAH box helicase 672 813 3.6E-15 T 06-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 BWK49_RS07500 0510f8a7e10a86ea66b1b6ff9bd967ab 1223 SMART SM00490 873 957 1.7E-17 T 06-07-2017 IPR001650 Helicase, C-terminal BWK49_RS07500 0510f8a7e10a86ea66b1b6ff9bd967ab 1223 Gene3D G3DSA:3.30.2060.10 158 237 1.5E-16 T 06-07-2017 BWK49_RS07500 0510f8a7e10a86ea66b1b6ff9bd967ab 1223 SUPERFAMILY SSF141259 515 593 9.68E-18 T 06-07-2017 IPR003711 CarD-like/TRCF domain BWK49_RS07500 0510f8a7e10a86ea66b1b6ff9bd967ab 1223 SUPERFAMILY SSF52540 829 1037 1.46E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS07500 0510f8a7e10a86ea66b1b6ff9bd967ab 1223 SUPERFAMILY SSF52540 46 349 2.01E-68 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS07500 0510f8a7e10a86ea66b1b6ff9bd967ab 1223 SMART SM00487 647 837 6.6E-28 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain BWK49_RS07500 0510f8a7e10a86ea66b1b6ff9bd967ab 1223 SMART SM01058 522 623 6.0E-46 T 06-07-2017 IPR003711 CarD-like/TRCF domain BWK49_RS07500 0510f8a7e10a86ea66b1b6ff9bd967ab 1223 Gene3D G3DSA:3.40.50.300 636 831 1.7E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS07500 0510f8a7e10a86ea66b1b6ff9bd967ab 1223 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 175 1130 0.0 T 06-07-2017 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 BWK49_RS07500 0510f8a7e10a86ea66b1b6ff9bd967ab 1223 SUPERFAMILY SSF52540 397 503 2.47E-8 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS18240 1c708207f8d00ec39eb41d60bbe6163e 329 SUPERFAMILY SSF51430 4 310 3.67E-100 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain BWK49_RS18240 1c708207f8d00ec39eb41d60bbe6163e 329 Gene3D G3DSA:3.20.20.100 2 319 8.9E-105 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain BWK49_RS18240 1c708207f8d00ec39eb41d60bbe6163e 329 PRINTS PR00069 Aldo-keto reductase signature 141 158 3.2E-11 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 BWK49_RS18240 1c708207f8d00ec39eb41d60bbe6163e 329 PRINTS PR00069 Aldo-keto reductase signature 110 128 3.2E-11 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 BWK49_RS18240 1c708207f8d00ec39eb41d60bbe6163e 329 Pfam PF00248 Aldo/keto reductase family 16 310 3.9E-79 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain BWK49_RS18240 1c708207f8d00ec39eb41d60bbe6163e 329 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 141 158 - T 06-07-2017 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 BWK49_RS25455 433156aec69d91770301d589ed696a68 228 Pfam PF00440 Bacterial regulatory proteins, tetR family 33 63 1.5E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS25455 433156aec69d91770301d589ed696a68 228 Gene3D G3DSA:1.10.357.10 44 195 2.3E-18 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS25455 433156aec69d91770301d589ed696a68 228 Gene3D G3DSA:1.10.10.60 4 43 2.7E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS25455 433156aec69d91770301d589ed696a68 228 SUPERFAMILY SSF46689 5 72 1.94E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS25455 433156aec69d91770301d589ed696a68 228 SUPERFAMILY SSF48498 86 196 1.41E-23 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS28400 5cd9ba93c9979753ac6be0d1fda15063 973 Gene3D G3DSA:3.40.50.300 466 646 1.0E-24 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS28400 5cd9ba93c9979753ac6be0d1fda15063 973 SUPERFAMILY SSF52540 687 857 9.3E-24 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS28400 5cd9ba93c9979753ac6be0d1fda15063 973 SUPERFAMILY SSF52540 583 648 9.3E-24 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS28400 5cd9ba93c9979753ac6be0d1fda15063 973 SMART SM00382 489 618 0.0076 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS28400 5cd9ba93c9979753ac6be0d1fda15063 973 SUPERFAMILY SSF55464 38 324 8.24E-64 T 06-07-2017 BWK49_RS28400 5cd9ba93c9979753ac6be0d1fda15063 973 Pfam PF13604 AAA domain 474 669 6.3E-50 T 06-07-2017 BWK49_RS28400 5cd9ba93c9979753ac6be0d1fda15063 973 SUPERFAMILY SSF52540 472 665 7.77E-25 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS28400 5cd9ba93c9979753ac6be0d1fda15063 973 Pfam PF08751 TrwC relaxase 24 319 2.3E-63 T 06-07-2017 IPR014862 TrwC relaxase BWK49_RS16035 8e9661af7c3a1f5c22b7814744676ea3 319 Gene3D G3DSA:3.30.2010.10 140 198 1.9E-11 T 06-07-2017 BWK49_RS16035 8e9661af7c3a1f5c22b7814744676ea3 319 Pfam PF01435 Peptidase family M48 139 213 5.9E-10 T 06-07-2017 IPR001915 Peptidase M48 GO:0004222|GO:0006508 BWK49_RS22835 13aa6961a7a6dabb489d017e64985a0a 327 Pfam PF03193 Protein of unknown function, DUF258 97 263 4.6E-42 T 06-07-2017 IPR010914 RsgA type GTPase domain GO:0003924|GO:0005525 BWK49_RS22835 13aa6961a7a6dabb489d017e64985a0a 327 Gene3D G3DSA:1.10.40.50 265 304 5.2E-5 T 06-07-2017 BWK49_RS22835 13aa6961a7a6dabb489d017e64985a0a 327 SUPERFAMILY SSF52540 113 285 1.27E-36 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS22835 13aa6961a7a6dabb489d017e64985a0a 327 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 71 303 3.6E-41 T 06-07-2017 IPR004881 Ribosome biogenesis GTPase RsgA, putative GO:0003924|GO:0005525 BWK49_RS22835 13aa6961a7a6dabb489d017e64985a0a 327 Gene3D G3DSA:3.40.50.300 113 263 1.5E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS11880 5dead1438280f279982f9fb99f343dc8 401 Gene3D G3DSA:3.20.20.140 9 395 3.4E-63 T 06-07-2017 BWK49_RS11880 5dead1438280f279982f9fb99f343dc8 401 SUPERFAMILY SSF51556 67 394 1.36E-63 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS11880 5dead1438280f279982f9fb99f343dc8 401 SUPERFAMILY SSF51556 10 37 1.36E-63 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS11880 5dead1438280f279982f9fb99f343dc8 401 Pfam PF04909 Amidohydrolase 77 392 9.1E-27 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 BWK49_RS17790 16b26cc0840623c01b8ce74cb22ed2fd 625 Pfam PF01642 Methylmalonyl-CoA mutase 49 534 3.6E-126 T 06-07-2017 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 BWK49_RS17790 16b26cc0840623c01b8ce74cb22ed2fd 625 Gene3D G3DSA:3.40.50.280 493 624 1.3E-41 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 BWK49_RS17790 16b26cc0840623c01b8ce74cb22ed2fd 625 SUPERFAMILY SSF52242 476 625 2.75E-32 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 BWK49_RS17790 16b26cc0840623c01b8ce74cb22ed2fd 625 TIGRFAM TIGR00642 mmCoA_mut_beta: methylmalonyl-CoA mutase, small subunit 6 625 9.0E-236 T 06-07-2017 IPR004608 Methylmalonyl-CoA mutase, beta chain GO:0004494|GO:0019652|GO:0031419 KEGG: 00280+5.4.99.2|KEGG: 00630+5.4.99.2|KEGG: 00640+5.4.99.2|KEGG: 00720+5.4.99.2|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384 BWK49_RS17790 16b26cc0840623c01b8ce74cb22ed2fd 625 Gene3D G3DSA:3.20.20.240 47 492 1.7E-119 T 06-07-2017 IPR014348 Cobalamin (vitamin B12)-dependent enzyme, catalytic subdomain GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 BWK49_RS17790 16b26cc0840623c01b8ce74cb22ed2fd 625 ProSitePatterns PS00544 Methylmalonyl-CoA mutase signature. 368 393 - T 06-07-2017 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 BWK49_RS17790 16b26cc0840623c01b8ce74cb22ed2fd 625 SUPERFAMILY SSF51703 34 529 2.12E-129 T 06-07-2017 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 BWK49_RS10385 222e177e843484f371d9e170ed6f3eb9 407 Gene3D G3DSA:1.10.150.130 45 147 9.5E-8 T 06-07-2017 IPR023109 Integrase/recombinase, N-terminal BWK49_RS10385 222e177e843484f371d9e170ed6f3eb9 407 SUPERFAMILY SSF56349 196 364 1.32E-29 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 BWK49_RS10385 222e177e843484f371d9e170ed6f3eb9 407 Gene3D G3DSA:1.10.443.10 197 366 1.3E-28 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 BWK49_RS10385 222e177e843484f371d9e170ed6f3eb9 407 Pfam PF00589 Phage integrase family 199 362 1.7E-18 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 BWK49_RS05035 222e177e843484f371d9e170ed6f3eb9 407 Gene3D G3DSA:1.10.150.130 45 147 9.5E-8 T 06-07-2017 IPR023109 Integrase/recombinase, N-terminal BWK49_RS05035 222e177e843484f371d9e170ed6f3eb9 407 SUPERFAMILY SSF56349 196 364 1.32E-29 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 BWK49_RS05035 222e177e843484f371d9e170ed6f3eb9 407 Gene3D G3DSA:1.10.443.10 197 366 1.3E-28 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 BWK49_RS05035 222e177e843484f371d9e170ed6f3eb9 407 Pfam PF00589 Phage integrase family 199 362 1.7E-18 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 BWK49_RS22495 222e177e843484f371d9e170ed6f3eb9 407 Gene3D G3DSA:1.10.150.130 45 147 9.5E-8 T 06-07-2017 IPR023109 Integrase/recombinase, N-terminal BWK49_RS22495 222e177e843484f371d9e170ed6f3eb9 407 SUPERFAMILY SSF56349 196 364 1.32E-29 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 BWK49_RS22495 222e177e843484f371d9e170ed6f3eb9 407 Gene3D G3DSA:1.10.443.10 197 366 1.3E-28 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 BWK49_RS22495 222e177e843484f371d9e170ed6f3eb9 407 Pfam PF00589 Phage integrase family 199 362 1.7E-18 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 BWK49_RS10500 222e177e843484f371d9e170ed6f3eb9 407 Gene3D G3DSA:1.10.150.130 45 147 9.5E-8 T 06-07-2017 IPR023109 Integrase/recombinase, N-terminal BWK49_RS10500 222e177e843484f371d9e170ed6f3eb9 407 SUPERFAMILY SSF56349 196 364 1.32E-29 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 BWK49_RS10500 222e177e843484f371d9e170ed6f3eb9 407 Gene3D G3DSA:1.10.443.10 197 366 1.3E-28 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 BWK49_RS10500 222e177e843484f371d9e170ed6f3eb9 407 Pfam PF00589 Phage integrase family 199 362 1.7E-18 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 BWK49_RS25260 d6bdd8febdf7601a811984120a392c9b 315 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 219 296 5.0E-21 T 06-07-2017 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 BWK49_RS25260 d6bdd8febdf7601a811984120a392c9b 315 Gene3D G3DSA:3.40.190.10 2 102 6.2E-30 T 06-07-2017 BWK49_RS25260 d6bdd8febdf7601a811984120a392c9b 315 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 2 296 3.3E-85 T 06-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 BWK49_RS25260 d6bdd8febdf7601a811984120a392c9b 315 PRINTS PR00151 Porphobilinogen deaminase signature 222 239 1.8E-22 T 06-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 BWK49_RS25260 d6bdd8febdf7601a811984120a392c9b 315 PRINTS PR00151 Porphobilinogen deaminase signature 68 87 1.8E-22 T 06-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 BWK49_RS25260 d6bdd8febdf7601a811984120a392c9b 315 PRINTS PR00151 Porphobilinogen deaminase signature 116 133 1.8E-22 T 06-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 BWK49_RS25260 d6bdd8febdf7601a811984120a392c9b 315 PRINTS PR00151 Porphobilinogen deaminase signature 135 152 1.8E-22 T 06-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 BWK49_RS25260 d6bdd8febdf7601a811984120a392c9b 315 PIRSF PIRSF001438 1 312 8.8E-103 T 06-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 BWK49_RS25260 d6bdd8febdf7601a811984120a392c9b 315 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 2 204 1.5E-62 T 06-07-2017 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 BWK49_RS25260 d6bdd8febdf7601a811984120a392c9b 315 Gene3D G3DSA:3.40.190.10 103 191 1.1E-32 T 06-07-2017 BWK49_RS25260 d6bdd8febdf7601a811984120a392c9b 315 SUPERFAMILY SSF54782 212 309 1.1E-19 T 06-07-2017 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 BWK49_RS25260 d6bdd8febdf7601a811984120a392c9b 315 SUPERFAMILY SSF53850 2 210 1.13E-62 T 06-07-2017 BWK49_RS25260 d6bdd8febdf7601a811984120a392c9b 315 Gene3D G3DSA:3.30.160.40 213 305 4.3E-23 T 06-07-2017 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 BWK49_RS25260 d6bdd8febdf7601a811984120a392c9b 315 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 223 239 - T 06-07-2017 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 BWK49_RS25260 d6bdd8febdf7601a811984120a392c9b 315 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 1 298 34.068 T 06-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 BWK49_RS09765 3f5ea53924476264723016fa24b437cb 256 SUPERFAMILY SSF52096 3 254 1.61E-61 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS09765 3f5ea53924476264723016fa24b437cb 256 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 230 7.2E-47 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 BWK49_RS09765 3f5ea53924476264723016fa24b437cb 256 Gene3D G3DSA:3.90.226.10 3 254 3.1E-62 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS09765 3f5ea53924476264723016fa24b437cb 256 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 101 121 - T 06-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 BWK49_RS09710 ce91d168332364faf5fe60e667926d05 450 SUPERFAMILY SSF103473 19 440 1.57E-28 T 06-07-2017 IPR020846 Major facilitator superfamily domain BWK49_RS09710 ce91d168332364faf5fe60e667926d05 450 Gene3D G3DSA:1.20.1250.20 254 438 1.8E-16 T 06-07-2017 BWK49_RS09710 ce91d168332364faf5fe60e667926d05 450 Pfam PF11700 Vacuole effluxer Atg22 like 148 436 1.6E-22 T 06-07-2017 IPR024671 Autophagy-related protein 22-like BWK49_RS06195 160b352e6fa7c8a999da1fc54860545c 434 SMART SM00928 322 367 2.5E-7 T 06-07-2017 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS06195 160b352e6fa7c8a999da1fc54860545c 434 SUPERFAMILY SSF142984 240 318 1.44E-13 T 06-07-2017 BWK49_RS06195 160b352e6fa7c8a999da1fc54860545c 434 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 324 407 5.9E-17 T 06-07-2017 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS06195 160b352e6fa7c8a999da1fc54860545c 434 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 52 216 9.8E-35 T 06-07-2017 IPR011538 NADH-ubiquinone oxidoreductase 51 kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS06195 160b352e6fa7c8a999da1fc54860545c 434 SUPERFAMILY SSF140490 318 413 2.62E-20 T 06-07-2017 BWK49_RS06195 160b352e6fa7c8a999da1fc54860545c 434 SUPERFAMILY SSF142019 28 237 3.92E-48 T 06-07-2017 BWK49_RS23120 c7a7a8c9f28c59abd0c463a8deb1cdb6 533 SMART SM00387 402 518 1.6E-31 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS23120 c7a7a8c9f28c59abd0c463a8deb1cdb6 533 Pfam PF05227 CHASE3 domain 55 173 5.4E-25 T 06-07-2017 IPR007891 CHASE3 BWK49_RS23120 c7a7a8c9f28c59abd0c463a8deb1cdb6 533 PRINTS PR00344 Bacterial sensor protein C-terminal signature 478 496 4.5E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 BWK49_RS23120 c7a7a8c9f28c59abd0c463a8deb1cdb6 533 PRINTS PR00344 Bacterial sensor protein C-terminal signature 445 459 4.5E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 BWK49_RS23120 c7a7a8c9f28c59abd0c463a8deb1cdb6 533 PRINTS PR00344 Bacterial sensor protein C-terminal signature 502 515 4.5E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 BWK49_RS23120 c7a7a8c9f28c59abd0c463a8deb1cdb6 533 SUPERFAMILY SSF47384 278 357 1.35E-16 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 BWK49_RS23120 c7a7a8c9f28c59abd0c463a8deb1cdb6 533 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 402 516 4.7E-22 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS23120 c7a7a8c9f28c59abd0c463a8deb1cdb6 533 SUPERFAMILY SSF158472 218 266 2.22E-6 T 06-07-2017 BWK49_RS23120 c7a7a8c9f28c59abd0c463a8deb1cdb6 533 Pfam PF00672 HAMP domain 197 265 3.9E-9 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 BWK49_RS23120 c7a7a8c9f28c59abd0c463a8deb1cdb6 533 Gene3D G3DSA:1.10.287.130 283 355 2.5E-9 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 BWK49_RS23120 c7a7a8c9f28c59abd0c463a8deb1cdb6 533 Pfam PF00512 His Kinase A (phospho-acceptor) domain 292 356 3.4E-10 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 BWK49_RS23120 c7a7a8c9f28c59abd0c463a8deb1cdb6 533 Gene3D G3DSA:3.30.565.10 362 523 4.8E-34 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS23120 c7a7a8c9f28c59abd0c463a8deb1cdb6 533 SMART SM00304 216 269 0.0068 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 BWK49_RS23120 c7a7a8c9f28c59abd0c463a8deb1cdb6 533 SMART SM00388 291 359 1.1E-9 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 BWK49_RS23120 c7a7a8c9f28c59abd0c463a8deb1cdb6 533 SUPERFAMILY SSF55874 348 516 4.85E-36 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS23155 7975ad1e2ca52f43de7b393afd7ba6ee 277 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 32 275 1.0E-33 T 06-07-2017 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 Reactome: R-HSA-196780|Reactome: R-HSA-3371599 BWK49_RS23155 7975ad1e2ca52f43de7b393afd7ba6ee 277 Gene3D G3DSA:2.30.30.100 231 273 2.7E-6 T 06-07-2017 BWK49_RS23155 7975ad1e2ca52f43de7b393afd7ba6ee 277 Pfam PF02237 Biotin protein ligase C terminal domain 229 275 3.0E-8 T 06-07-2017 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 BWK49_RS23155 7975ad1e2ca52f43de7b393afd7ba6ee 277 SUPERFAMILY SSF55681 21 211 2.15E-37 T 06-07-2017 BWK49_RS23155 7975ad1e2ca52f43de7b393afd7ba6ee 277 Gene3D G3DSA:3.30.930.10 27 226 1.8E-43 T 06-07-2017 BWK49_RS14520 a48eb075f1e69d161be625fb450a59f9 158 Gene3D G3DSA:3.10.450.50 6 107 5.1E-12 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS14520 a48eb075f1e69d161be625fb450a59f9 158 SUPERFAMILY SSF54427 3 131 8.6E-24 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS14520 a48eb075f1e69d161be625fb450a59f9 158 Pfam PF12680 SnoaL-like domain 26 110 7.1E-13 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain BWK49_RS22320 6786587d8cd15ad05db7481f7abcbbf1 221 ProSitePatterns PS00622 LuxR-type HTH domain signature. 172 199 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS22320 6786587d8cd15ad05db7481f7abcbbf1 221 Pfam PF00196 Bacterial regulatory proteins, luxR family 157 212 2.2E-21 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS22320 6786587d8cd15ad05db7481f7abcbbf1 221 Gene3D G3DSA:1.10.10.10 125 217 6.1E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS22320 6786587d8cd15ad05db7481f7abcbbf1 221 SMART SM00421 155 212 1.3E-24 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS22320 6786587d8cd15ad05db7481f7abcbbf1 221 SUPERFAMILY SSF52172 7 185 9.65E-30 T 06-07-2017 IPR011006 CheY-like superfamily BWK49_RS22320 6786587d8cd15ad05db7481f7abcbbf1 221 Pfam PF00072 Response regulator receiver domain 10 120 7.4E-23 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 BWK49_RS22320 6786587d8cd15ad05db7481f7abcbbf1 221 Gene3D G3DSA:3.40.50.2300 7 124 4.8E-30 T 06-07-2017 BWK49_RS22320 6786587d8cd15ad05db7481f7abcbbf1 221 SMART SM00448 8 120 7.1E-27 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 BWK49_RS22320 6786587d8cd15ad05db7481f7abcbbf1 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 172 7.2E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS22320 6786587d8cd15ad05db7481f7abcbbf1 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 188 7.2E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS22320 6786587d8cd15ad05db7481f7abcbbf1 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 188 200 7.2E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS20560 bec7cd74fd35025dea08cef5e6263c34 430 Pfam PF00571 CBS domain 341 394 7.3E-9 T 06-07-2017 IPR000644 CBS domain BWK49_RS20560 bec7cd74fd35025dea08cef5e6263c34 430 Pfam PF00571 CBS domain 277 335 9.0E-5 T 06-07-2017 IPR000644 CBS domain BWK49_RS20560 bec7cd74fd35025dea08cef5e6263c34 430 SUPERFAMILY SSF54631 276 400 3.41E-24 T 06-07-2017 BWK49_RS20560 bec7cd74fd35025dea08cef5e6263c34 430 Gene3D G3DSA:3.10.580.10 276 394 2.1E-18 T 06-07-2017 BWK49_RS20560 bec7cd74fd35025dea08cef5e6263c34 430 Pfam PF03448 MgtE intracellular N domain 172 274 1.4E-20 T 06-07-2017 IPR006668 Magnesium transporter, MgtE intracellular domain BWK49_RS20560 bec7cd74fd35025dea08cef5e6263c34 430 SUPERFAMILY SSF158791 146 272 8.76E-21 T 06-07-2017 BWK49_RS20560 bec7cd74fd35025dea08cef5e6263c34 430 SMART SM00116 348 396 1.0E-5 T 06-07-2017 IPR000644 CBS domain BWK49_RS20560 bec7cd74fd35025dea08cef5e6263c34 430 SMART SM00116 283 337 16.0 T 06-07-2017 IPR000644 CBS domain BWK49_RS20560 bec7cd74fd35025dea08cef5e6263c34 430 Gene3D G3DSA:1.25.60.10 145 270 9.2E-23 T 06-07-2017 BWK49_RS20560 bec7cd74fd35025dea08cef5e6263c34 430 SMART SM00924 171 276 2.7E-23 T 06-07-2017 IPR006668 Magnesium transporter, MgtE intracellular domain BWK49_RS00255 e4004beedcec92743619a0f278c33729 113 ProDom PD029828 TRANSMEMBRANE MEMBRANE ML0030 POSSIBLE RV0039C/MT0044 1 112 5.0E-35 T 06-07-2017 BWK49_RS26665 e572e0bccda072fada588d7d0b73ed0d 647 Gene3D G3DSA:3.90.700.10 250 383 2.2E-35 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 BWK49_RS26665 e572e0bccda072fada588d7d0b73ed0d 647 SUPERFAMILY SSF51905 393 464 1.37E-67 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS26665 e572e0bccda072fada588d7d0b73ed0d 647 SUPERFAMILY SSF51905 4 270 1.37E-67 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS26665 e572e0bccda072fada588d7d0b73ed0d 647 Gene3D G3DSA:3.50.50.60 385 450 6.2E-103 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS26665 e572e0bccda072fada588d7d0b73ed0d 647 Gene3D G3DSA:3.50.50.60 4 249 6.2E-103 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS26665 e572e0bccda072fada588d7d0b73ed0d 647 SUPERFAMILY SSF46977 481 639 1.44E-42 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 BWK49_RS26665 e572e0bccda072fada588d7d0b73ed0d 647 Pfam PF02910 Fumarate reductase flavoprotein C-term 490 587 1.1E-23 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 BWK49_RS26665 e572e0bccda072fada588d7d0b73ed0d 647 Gene3D G3DSA:1.20.58.100 461 573 8.8E-33 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 BWK49_RS26665 e572e0bccda072fada588d7d0b73ed0d 647 Pfam PF00890 FAD binding domain 10 429 4.0E-87 T 06-07-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 BWK49_RS26665 e572e0bccda072fada588d7d0b73ed0d 647 PIRSF PIRSF000171 1 609 6.9E-35 T 06-07-2017 IPR030664 Succinate dehydrogenase/fumarate reductase, alpha/adenylylsulphate reductase subunit Reactome: R-HSA-611105|Reactome: R-HSA-71403 BWK49_RS26665 e572e0bccda072fada588d7d0b73ed0d 647 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 10 32 4.0E-8 T 06-07-2017 BWK49_RS26665 e572e0bccda072fada588d7d0b73ed0d 647 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 438 458 4.0E-8 T 06-07-2017 BWK49_RS26665 e572e0bccda072fada588d7d0b73ed0d 647 SUPERFAMILY SSF56425 243 389 2.24E-31 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 BWK49_RS26665 e572e0bccda072fada588d7d0b73ed0d 647 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 393 415 3.5E-5 T 06-07-2017 BWK49_RS26665 e572e0bccda072fada588d7d0b73ed0d 647 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 3.5E-5 T 06-07-2017 BWK49_RS00700 110aa285659435305dd12f035bcc386f 285 Gene3D G3DSA:3.20.20.30 1 283 2.3E-67 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS00700 110aa285659435305dd12f035bcc386f 285 SUPERFAMILY SSF51679 1 282 5.5E-60 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS00700 110aa285659435305dd12f035bcc386f 285 Pfam PF00296 Luciferase-like monooxygenase 9 255 3.4E-52 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS00700 110aa285659435305dd12f035bcc386f 285 TIGRFAM TIGR03619 F420_Rv2161c: probable F420-dependent oxidoreductase, Rv2161c family 21 261 1.5E-84 T 06-07-2017 IPR019921 Luciferase-like, F420-dependent oxidoreductase, Rv2161c, predicted BWK49_RS08770 1d56216fec6104c3683791cc0b19696f 414 SUPERFAMILY SSF53474 32 348 4.13E-35 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS08770 1d56216fec6104c3683791cc0b19696f 414 Pfam PF00561 alpha/beta hydrolase fold 49 159 9.5E-15 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS08770 1d56216fec6104c3683791cc0b19696f 414 Gene3D G3DSA:3.40.50.1820 33 197 1.5E-38 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS08770 1d56216fec6104c3683791cc0b19696f 414 Gene3D G3DSA:3.40.50.1820 260 346 1.5E-38 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS19780 badd0b4666d42421d793862d58e1c7bd 583 Gene3D G3DSA:3.40.50.720 314 548 1.3E-65 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS19780 badd0b4666d42421d793862d58e1c7bd 583 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 315 496 2.2E-4 T 06-07-2017 BWK49_RS19780 badd0b4666d42421d793862d58e1c7bd 583 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 486 503 2.4E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS19780 badd0b4666d42421d793862d58e1c7bd 583 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 439 455 2.4E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS19780 badd0b4666d42421d793862d58e1c7bd 583 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 316 333 2.4E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS19780 badd0b4666d42421d793862d58e1c7bd 583 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 465 484 2.4E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS19780 badd0b4666d42421d793862d58e1c7bd 583 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 391 402 2.4E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS19780 badd0b4666d42421d793862d58e1c7bd 583 Pfam PF00106 short chain dehydrogenase 315 505 1.2E-51 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS19780 badd0b4666d42421d793862d58e1c7bd 583 Pfam PF00561 alpha/beta hydrolase fold 28 134 1.1E-19 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS19780 badd0b4666d42421d793862d58e1c7bd 583 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 452 480 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS19780 badd0b4666d42421d793862d58e1c7bd 583 SUPERFAMILY SSF51735 312 572 2.05E-63 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS19780 badd0b4666d42421d793862d58e1c7bd 583 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 465 484 2.2E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS19780 badd0b4666d42421d793862d58e1c7bd 583 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 445 453 2.2E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS19780 badd0b4666d42421d793862d58e1c7bd 583 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 391 402 2.2E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS19780 badd0b4666d42421d793862d58e1c7bd 583 SUPERFAMILY SSF53474 7 294 9.43E-44 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS19780 badd0b4666d42421d793862d58e1c7bd 583 Gene3D G3DSA:3.40.50.1820 3 294 1.8E-51 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS02520 09d9d3d8c8662fe862a67fee6de7da7e 639 Pfam PF00682 HMGL-like 70 349 6.1E-76 T 06-07-2017 IPR000891 Pyruvate carboxyltransferase GO:0003824 BWK49_RS02520 09d9d3d8c8662fe862a67fee6de7da7e 639 TIGRFAM TIGR00970 leuA_yeast: 2-isopropylmalate synthase 39 638 2.9E-304 T 06-07-2017 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 BWK49_RS02520 09d9d3d8c8662fe862a67fee6de7da7e 639 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 279 292 - T 06-07-2017 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 BWK49_RS02520 09d9d3d8c8662fe862a67fee6de7da7e 639 SUPERFAMILY SSF89000 434 483 3.02E-15 T 06-07-2017 BWK49_RS02520 09d9d3d8c8662fe862a67fee6de7da7e 639 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 76 92 - T 06-07-2017 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 BWK49_RS02520 09d9d3d8c8662fe862a67fee6de7da7e 639 Pfam PF08502 LeuA allosteric (dimerisation) domain 468 636 2.7E-26 T 06-07-2017 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 BWK49_RS02520 09d9d3d8c8662fe862a67fee6de7da7e 639 SUPERFAMILY SSF110921 491 636 6.8E-41 T 06-07-2017 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 BWK49_RS02520 09d9d3d8c8662fe862a67fee6de7da7e 639 Hamap MF_00572 2-isopropylmalate synthase [leuA]. 40 638 54.538 T 06-07-2017 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 BWK49_RS02520 09d9d3d8c8662fe862a67fee6de7da7e 639 SUPERFAMILY SSF51569 58 366 4.4E-95 T 06-07-2017 BWK49_RS02520 09d9d3d8c8662fe862a67fee6de7da7e 639 Gene3D G3DSA:3.20.20.70 48 440 1.9E-145 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 BWK49_RS02520 09d9d3d8c8662fe862a67fee6de7da7e 639 SMART SM00917 468 637 2.1E-28 T 06-07-2017 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 BWK49_RS12890 d4451d16b8d43d0b19dfe8b8e379575c 567 SUPERFAMILY SSF81342 21 309 7.22E-55 T 06-07-2017 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 BWK49_RS12890 d4451d16b8d43d0b19dfe8b8e379575c 567 Gene3D G3DSA:1.20.810.10 21 450 3.8E-78 T 06-07-2017 IPR027387 Cytochrome b/b6-like domain Reactome: R-HSA-611105 BWK49_RS12890 d4451d16b8d43d0b19dfe8b8e379575c 567 Pfam PF13631 Cytochrome b(N-terminal)/b6/petB 120 304 1.9E-56 T 06-07-2017 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 BWK49_RS24095 2f2b292b88fa9641cc7b4c0c70ae01b7 183 Pfam PF04542 Sigma-70 region 2 32 95 3.5E-7 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS24095 2f2b292b88fa9641cc7b4c0c70ae01b7 183 SUPERFAMILY SSF88659 105 172 6.73E-11 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS24095 2f2b292b88fa9641cc7b4c0c70ae01b7 183 Gene3D G3DSA:1.10.10.10 122 172 5.2E-10 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS24095 2f2b292b88fa9641cc7b4c0c70ae01b7 183 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 30 172 1.4E-16 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS24095 2f2b292b88fa9641cc7b4c0c70ae01b7 183 SUPERFAMILY SSF88946 27 94 1.18E-10 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS24095 2f2b292b88fa9641cc7b4c0c70ae01b7 183 Gene3D G3DSA:1.10.1740.10 28 118 7.8E-11 T 06-07-2017 BWK49_RS24095 2f2b292b88fa9641cc7b4c0c70ae01b7 183 Pfam PF08281 Sigma-70, region 4 122 172 6.4E-9 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS25660 7589321b1792846535fe25b34d961581 233 Pfam PF02666 Phosphatidylserine decarboxylase 63 229 2.5E-30 T 06-07-2017 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 BWK49_RS25660 7589321b1792846535fe25b34d961581 233 TIGRFAM TIGR00164 PS_decarb_rel: phosphatidylserine decarboxylase homolog 32 231 1.2E-47 T 06-07-2017 IPR033175 Phosphatidylserine decarboxylase, archaeal-type KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 BWK49_RS25660 7589321b1792846535fe25b34d961581 233 Hamap MF_00664 Phosphatidylserine decarboxylase proenzyme [psd]. 25 233 34.912 T 06-07-2017 IPR033175 Phosphatidylserine decarboxylase, archaeal-type KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 BWK49_RS21470 67898ec6cbbe5c54ba39694ec94decd7 321 SUPERFAMILY SSF56112 11 318 9.53E-39 T 06-07-2017 IPR011009 Protein kinase-like domain BWK49_RS21470 67898ec6cbbe5c54ba39694ec94decd7 321 Gene3D G3DSA:3.90.1200.10 106 276 4.0E-21 T 06-07-2017 BWK49_RS21470 67898ec6cbbe5c54ba39694ec94decd7 321 Pfam PF01636 Phosphotransferase enzyme family 23 236 6.0E-30 T 06-07-2017 IPR002575 Aminoglycoside phosphotransferase BWK49_RS07250 40f03238733d63003ea19c572937d705 283 SUPERFAMILY SSF53790 4 223 1.57E-67 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 BWK49_RS07250 40f03238733d63003ea19c572937d705 283 Gene3D G3DSA:3.40.1010.10 10 114 2.4E-7 T 06-07-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 BWK49_RS07250 40f03238733d63003ea19c572937d705 283 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 5 225 32.017 T 06-07-2017 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 BWK49_RS07250 40f03238733d63003ea19c572937d705 283 ProSitePatterns PS01296 RsmI AdoMet-dependent methyltransferase protein family signature. 85 96 - T 06-07-2017 IPR018063 SAM-dependent methyltransferase RsmI, conserved site GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 BWK49_RS07250 40f03238733d63003ea19c572937d705 283 PIRSF PIRSF005917 1 278 3.5E-85 T 06-07-2017 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 BWK49_RS07250 40f03238733d63003ea19c572937d705 283 Gene3D G3DSA:3.30.950.10 115 226 2.3E-40 T 06-07-2017 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 BWK49_RS07250 40f03238733d63003ea19c572937d705 283 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 11 208 1.8E-25 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 BWK49_RS07250 40f03238733d63003ea19c572937d705 283 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 9 273 4.1E-57 T 06-07-2017 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 BWK49_RS20870 bbeb6bcbdd58262203906c0171f8bba3 479 Gene3D G3DSA:3.30.499.10 8 173 4.0E-24 T 06-07-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 BWK49_RS20870 bbeb6bcbdd58262203906c0171f8bba3 479 PRINTS PR00415 Aconitase family signature 412 425 2.8E-48 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 BWK49_RS20870 bbeb6bcbdd58262203906c0171f8bba3 479 PRINTS PR00415 Aconitase family signature 121 129 2.8E-48 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 BWK49_RS20870 bbeb6bcbdd58262203906c0171f8bba3 479 PRINTS PR00415 Aconitase family signature 356 367 2.8E-48 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 BWK49_RS20870 bbeb6bcbdd58262203906c0171f8bba3 479 PRINTS PR00415 Aconitase family signature 95 108 2.8E-48 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 BWK49_RS20870 bbeb6bcbdd58262203906c0171f8bba3 479 PRINTS PR00415 Aconitase family signature 146 161 2.8E-48 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 BWK49_RS20870 bbeb6bcbdd58262203906c0171f8bba3 479 PRINTS PR00415 Aconitase family signature 208 221 2.8E-48 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 BWK49_RS20870 bbeb6bcbdd58262203906c0171f8bba3 479 PRINTS PR00415 Aconitase family signature 222 235 2.8E-48 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 BWK49_RS20870 bbeb6bcbdd58262203906c0171f8bba3 479 PRINTS PR00415 Aconitase family signature 299 313 2.8E-48 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 BWK49_RS20870 bbeb6bcbdd58262203906c0171f8bba3 479 PRINTS PR00415 Aconitase family signature 132 145 2.8E-48 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 BWK49_RS20870 bbeb6bcbdd58262203906c0171f8bba3 479 SUPERFAMILY SSF53732 8 477 1.96E-161 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 BWK49_RS20870 bbeb6bcbdd58262203906c0171f8bba3 479 Gene3D G3DSA:3.30.499.10 342 477 5.9E-58 T 06-07-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 BWK49_RS20870 bbeb6bcbdd58262203906c0171f8bba3 479 ProSitePatterns PS00450 Aconitase family signature 1. 352 368 - T 06-07-2017 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 BWK49_RS20870 bbeb6bcbdd58262203906c0171f8bba3 479 Pfam PF00330 Aconitase family (aconitate hydratase) 16 470 1.8E-153 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 BWK49_RS20870 bbeb6bcbdd58262203906c0171f8bba3 479 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 10 479 59.599 T 06-07-2017 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 BWK49_RS20870 bbeb6bcbdd58262203906c0171f8bba3 479 ProSitePatterns PS01244 Aconitase family signature 2. 412 425 - T 06-07-2017 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 BWK49_RS20870 bbeb6bcbdd58262203906c0171f8bba3 479 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 11 472 3.9E-221 T 06-07-2017 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 BWK49_RS20870 bbeb6bcbdd58262203906c0171f8bba3 479 Gene3D G3DSA:3.40.1060.10 179 293 1.2E-39 T 06-07-2017 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 BWK49_RS06680 d73d762425c911727da3373e692ea145 562 Gene3D G3DSA:3.30.70.20 4 78 4.4E-15 T 06-07-2017 BWK49_RS06680 d73d762425c911727da3373e692ea145 562 SUPERFAMILY SSF51971 112 319 2.41E-49 T 06-07-2017 BWK49_RS06680 d73d762425c911727da3373e692ea145 562 SUPERFAMILY SSF51971 365 412 2.41E-49 T 06-07-2017 BWK49_RS06680 d73d762425c911727da3373e692ea145 562 Gene3D G3DSA:3.50.50.60 204 411 1.5E-52 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS06680 d73d762425c911727da3373e692ea145 562 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 115 270 9.2E-9 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS06680 d73d762425c911727da3373e692ea145 562 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 46 57 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site BWK49_RS06680 d73d762425c911727da3373e692ea145 562 PRINTS PR00419 Adrenodoxin reductase family signature 114 136 2.3E-19 T 06-07-2017 BWK49_RS06680 d73d762425c911727da3373e692ea145 562 PRINTS PR00419 Adrenodoxin reductase family signature 253 267 2.3E-19 T 06-07-2017 BWK49_RS06680 d73d762425c911727da3373e692ea145 562 PRINTS PR00419 Adrenodoxin reductase family signature 138 151 2.3E-19 T 06-07-2017 BWK49_RS06680 d73d762425c911727da3373e692ea145 562 PRINTS PR00419 Adrenodoxin reductase family signature 181 191 2.3E-19 T 06-07-2017 BWK49_RS06680 d73d762425c911727da3373e692ea145 562 Gene3D G3DSA:3.40.50.720 412 542 5.6E-73 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS06680 d73d762425c911727da3373e692ea145 562 Gene3D G3DSA:3.40.50.720 112 203 5.6E-73 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS06680 d73d762425c911727da3373e692ea145 562 SUPERFAMILY SSF54862 1 84 1.12E-18 T 06-07-2017 BWK49_RS06680 d73d762425c911727da3373e692ea145 562 Pfam PF00037 4Fe-4S binding domain 40 61 7.9E-8 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain BWK49_RS01855 e1874ff938218bd26fc823b87948c513 474 Gene3D G3DSA:3.40.605.10 2 252 1.0E-75 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 BWK49_RS01855 e1874ff938218bd26fc823b87948c513 474 Gene3D G3DSA:3.40.309.10 253 443 1.6E-59 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 BWK49_RS01855 e1874ff938218bd26fc823b87948c513 474 SUPERFAMILY SSF53720 9 468 5.5E-141 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 BWK49_RS01855 e1874ff938218bd26fc823b87948c513 474 Pfam PF00171 Aldehyde dehydrogenase family 11 468 2.5E-147 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 BWK49_RS01855 e1874ff938218bd26fc823b87948c513 474 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 239 246 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 BWK49_RS17010 8a726b4f3c470383d62015199ff60c0c 131 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 21 70 3.0E-21 T 06-07-2017 BWK49_RS17010 8a726b4f3c470383d62015199ff60c0c 131 Pfam PF00453 Ribosomal protein L20 3 109 2.4E-42 T 06-07-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS17010 8a726b4f3c470383d62015199ff60c0c 131 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 113 5.7E-42 T 06-07-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS17010 8a726b4f3c470383d62015199ff60c0c 131 PRINTS PR00062 Ribosomal protein L20 signature 12 41 6.4E-37 T 06-07-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS17010 8a726b4f3c470383d62015199ff60c0c 131 PRINTS PR00062 Ribosomal protein L20 signature 42 71 6.4E-37 T 06-07-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS17010 8a726b4f3c470383d62015199ff60c0c 131 PRINTS PR00062 Ribosomal protein L20 signature 75 101 6.4E-37 T 06-07-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS17010 8a726b4f3c470383d62015199ff60c0c 131 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 06-07-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS17010 8a726b4f3c470383d62015199ff60c0c 131 SUPERFAMILY SSF74731 3 117 1.96E-43 T 06-07-2017 BWK49_RS17010 8a726b4f3c470383d62015199ff60c0c 131 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 27.644 T 06-07-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS17010 8a726b4f3c470383d62015199ff60c0c 131 Gene3D G3DSA:1.10.1900.20 56 117 3.0E-28 T 06-07-2017 BWK49_RS12830 deb341cdcd4ecddb0396296b4234f837 353 Pfam PF02277 Phosphoribosyltransferase 6 342 1.5E-129 T 06-07-2017 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 BWK49_RS12830 deb341cdcd4ecddb0396296b4234f837 353 Hamap MF_00230 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase [cobT]. 8 344 36.922 T 06-07-2017 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 BWK49_RS12830 deb341cdcd4ecddb0396296b4234f837 353 SUPERFAMILY SSF52733 5 344 4.19E-112 T 06-07-2017 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 BWK49_RS12830 deb341cdcd4ecddb0396296b4234f837 353 Gene3D G3DSA:1.10.1610.10 6 68 1.5E-31 T 06-07-2017 IPR023195 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 BWK49_RS12830 deb341cdcd4ecddb0396296b4234f837 353 TIGRFAM TIGR03160 cobT_DBIPRT: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 10 342 4.5E-123 T 06-07-2017 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 BWK49_RS12830 deb341cdcd4ecddb0396296b4234f837 353 Gene3D G3DSA:3.40.50.10210 69 325 1.8E-103 T 06-07-2017 BWK49_RS09500 a4820ae5589ae400701500d7fe3b286f 311 Gene3D G3DSA:1.20.140.10 162 290 2.9E-18 T 06-07-2017 BWK49_RS09500 a4820ae5589ae400701500d7fe3b286f 311 SUPERFAMILY SSF47203 157 292 1.61E-21 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS09500 a4820ae5589ae400701500d7fe3b286f 311 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 165 293 8.3E-15 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS27805 27829436cc9382ad11e6566869e37aa3 538 Gene3D G3DSA:2.120.10.30 20 73 5.9E-5 T 06-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like BWK49_RS27805 27829436cc9382ad11e6566869e37aa3 538 SUPERFAMILY SSF101898 271 536 4.71E-26 T 06-07-2017 BWK49_RS27805 27829436cc9382ad11e6566869e37aa3 538 SUPERFAMILY SSF63829 82 303 7.85E-39 T 06-07-2017 BWK49_RS27805 27829436cc9382ad11e6566869e37aa3 538 SUPERFAMILY SSF50969 19 110 7.14E-7 T 06-07-2017 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like BWK49_RS27805 27829436cc9382ad11e6566869e37aa3 538 Gene3D G3DSA:2.120.10.30 83 302 7.0E-39 T 06-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like BWK49_RS27805 27829436cc9382ad11e6566869e37aa3 538 Gene3D G3DSA:2.120.10.30 323 537 5.0E-20 T 06-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like BWK49_RS27805 27829436cc9382ad11e6566869e37aa3 538 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 40 258 1.5E-12 T 06-07-2017 IPR013658 SMP-30/Gluconolactonase/LRE-like region BWK49_RS20290 216d3ecd125de5d2a9c9d7b37be0ba48 246 Gene3D G3DSA:3.40.1280.10 1 160 3.5E-63 T 06-07-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal BWK49_RS20290 216d3ecd125de5d2a9c9d7b37be0ba48 246 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 228 1.3E-66 T 06-07-2017 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 BWK49_RS20290 216d3ecd125de5d2a9c9d7b37be0ba48 246 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 22 224 7.8E-66 T 06-07-2017 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 BWK49_RS20290 216d3ecd125de5d2a9c9d7b37be0ba48 246 Gene3D G3DSA:1.10.1270.20 161 228 3.0E-25 T 06-07-2017 IPR023148 tRNA (guanine-N1-)-methyltransferase, C-terminal GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 BWK49_RS20290 216d3ecd125de5d2a9c9d7b37be0ba48 246 PIRSF PIRSF000386 1 239 2.2E-82 T 06-07-2017 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 BWK49_RS20290 216d3ecd125de5d2a9c9d7b37be0ba48 246 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 246 92.473 T 06-07-2017 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 BWK49_RS20290 216d3ecd125de5d2a9c9d7b37be0ba48 246 SUPERFAMILY SSF75217 1 228 7.19E-82 T 06-07-2017 IPR029028 Alpha/beta knot methyltransferases BWK49_RS10910 5c299b0d924c33a63d3331d07ccf8831 392 SUPERFAMILY SSF53901 11 235 4.45E-24 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS10910 5c299b0d924c33a63d3331d07ccf8831 392 SUPERFAMILY SSF53901 264 381 5.43E-11 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS10910 5c299b0d924c33a63d3331d07ccf8831 392 Gene3D G3DSA:3.40.47.10 205 232 4.0E-12 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS10910 5c299b0d924c33a63d3331d07ccf8831 392 Gene3D G3DSA:3.40.47.10 15 118 4.0E-12 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS10910 5c299b0d924c33a63d3331d07ccf8831 392 PIRSF PIRSF000429 8 343 2.5E-18 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 BWK49_RS24145 e518323d8dc34e552e3dd2f4b2407134 441 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 15 436 4.0E-129 T 06-07-2017 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 BWK49_RS24145 e518323d8dc34e552e3dd2f4b2407134 441 ProSitePatterns PS00756 Protein secY signature 2. 176 193 - T 06-07-2017 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 BWK49_RS24145 e518323d8dc34e552e3dd2f4b2407134 441 Hamap MF_01465 Protein translocase subunit SecY [secY]. 5 440 29.399 T 06-07-2017 IPR026593 Protein translocase subunit SecY BWK49_RS24145 e518323d8dc34e552e3dd2f4b2407134 441 ProSitePatterns PS00755 Protein secY signature 1. 75 94 - T 06-07-2017 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 BWK49_RS24145 e518323d8dc34e552e3dd2f4b2407134 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 183 206 6.5E-100 T 06-07-2017 BWK49_RS24145 e518323d8dc34e552e3dd2f4b2407134 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 157 182 6.5E-100 T 06-07-2017 BWK49_RS24145 e518323d8dc34e552e3dd2f4b2407134 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 115 138 6.5E-100 T 06-07-2017 BWK49_RS24145 e518323d8dc34e552e3dd2f4b2407134 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 270 289 6.5E-100 T 06-07-2017 BWK49_RS24145 e518323d8dc34e552e3dd2f4b2407134 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 373 391 6.5E-100 T 06-07-2017 BWK49_RS24145 e518323d8dc34e552e3dd2f4b2407134 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 74 94 6.5E-100 T 06-07-2017 BWK49_RS24145 e518323d8dc34e552e3dd2f4b2407134 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 18 36 6.5E-100 T 06-07-2017 BWK49_RS24145 e518323d8dc34e552e3dd2f4b2407134 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 318 340 6.5E-100 T 06-07-2017 BWK49_RS24145 e518323d8dc34e552e3dd2f4b2407134 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 409 427 6.5E-100 T 06-07-2017 BWK49_RS24145 e518323d8dc34e552e3dd2f4b2407134 441 SUPERFAMILY SSF103491 2 431 3.14E-119 T 06-07-2017 IPR023201 SecY subunit domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 BWK49_RS24145 e518323d8dc34e552e3dd2f4b2407134 441 PIRSF PIRSF004557 1 441 3.3E-114 T 06-07-2017 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 BWK49_RS24145 e518323d8dc34e552e3dd2f4b2407134 441 Pfam PF00344 SecY translocase 75 424 4.1E-113 T 06-07-2017 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 BWK49_RS24145 e518323d8dc34e552e3dd2f4b2407134 441 Gene3D G3DSA:1.10.3370.10 4 441 3.3E-151 T 06-07-2017 IPR023201 SecY subunit domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 BWK49_RS11480 f3b2fcbb06bb9f17a156daa0e1c4aeb0 289 Pfam PF01255 Putative undecaprenyl diphosphate synthase 67 287 1.6E-70 T 06-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 BWK49_RS11480 f3b2fcbb06bb9f17a156daa0e1c4aeb0 289 Gene3D G3DSA:3.40.1180.10 50 287 3.0E-89 T 06-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 BWK49_RS11480 f3b2fcbb06bb9f17a156daa0e1c4aeb0 289 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 60 287 7.3E-72 T 06-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 BWK49_RS11480 f3b2fcbb06bb9f17a156daa0e1c4aeb0 289 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 60 288 36.876 T 06-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 BWK49_RS11480 f3b2fcbb06bb9f17a156daa0e1c4aeb0 289 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 233 250 - T 06-07-2017 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 BWK49_RS11480 f3b2fcbb06bb9f17a156daa0e1c4aeb0 289 SUPERFAMILY SSF64005 56 282 1.01E-81 T 06-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 BWK49_RS23265 0941b3822a5befe12d27eda22c6f8269 251 SUPERFAMILY SSF81624 2 120 1.31E-24 T 06-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 BWK49_RS23265 0941b3822a5befe12d27eda22c6f8269 251 SUPERFAMILY SSF46946 118 183 3.83E-18 T 06-07-2017 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 BWK49_RS23265 0941b3822a5befe12d27eda22c6f8269 251 Gene3D G3DSA:3.20.190.10 2 119 1.1E-15 T 06-07-2017 BWK49_RS23265 0941b3822a5befe12d27eda22c6f8269 251 Gene3D G3DSA:1.10.8.50 120 251 2.4E-35 T 06-07-2017 BWK49_RS23265 0941b3822a5befe12d27eda22c6f8269 251 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 119 176 4.2E-10 T 06-07-2017 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 BWK49_RS23265 0941b3822a5befe12d27eda22c6f8269 251 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 90 1.4E-11 T 06-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 BWK49_RS23265 0941b3822a5befe12d27eda22c6f8269 251 SMART SM01232 119 207 1.1E-20 T 06-07-2017 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 BWK49_RS23265 0941b3822a5befe12d27eda22c6f8269 251 ProSitePatterns PS01242 Zinc finger FPG-type signature. 226 250 - T 06-07-2017 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 BWK49_RS23265 0941b3822a5befe12d27eda22c6f8269 251 SUPERFAMILY SSF57716 213 251 6.27E-10 T 06-07-2017 BWK49_RS23265 0941b3822a5befe12d27eda22c6f8269 251 SMART SM00898 2 105 2.6E-18 T 06-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 BWK49_RS03175 dc8aef45dce729632a3e69acc4dbf1f1 229 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 104 111 - T 06-07-2017 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 BWK49_RS03175 dc8aef45dce729632a3e69acc4dbf1f1 229 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 12 226 1.5E-67 T 06-07-2017 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 BWK49_RS03175 dc8aef45dce729632a3e69acc4dbf1f1 229 Gene3D G3DSA:3.90.550.10 10 228 2.1E-65 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases BWK49_RS03175 dc8aef45dce729632a3e69acc4dbf1f1 229 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 11 229 3.8E-76 T 06-07-2017 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 BWK49_RS03175 dc8aef45dce729632a3e69acc4dbf1f1 229 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 10 229 25.872 T 06-07-2017 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 BWK49_RS03175 dc8aef45dce729632a3e69acc4dbf1f1 229 SUPERFAMILY SSF53448 11 227 5.01E-52 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases BWK49_RS02755 a7b4450b6f80be67390f86e371c6203c 376 SUPERFAMILY SSF52540 226 287 7.66E-33 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS02755 a7b4450b6f80be67390f86e371c6203c 376 SUPERFAMILY SSF52540 18 181 7.66E-33 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS02755 a7b4450b6f80be67390f86e371c6203c 376 Gene3D G3DSA:3.40.50.300 15 176 1.6E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS02755 a7b4450b6f80be67390f86e371c6203c 376 Gene3D G3DSA:3.40.50.300 213 289 1.6E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS02755 a7b4450b6f80be67390f86e371c6203c 376 Pfam PF02374 Anion-transporting ATPase 20 287 2.2E-27 T 06-07-2017 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 BWK49_RS19665 d1761b11d15662ddc606e8ff18a7b391 300 Pfam PF00701 Dihydrodipicolinate synthetase family 13 294 3.5E-80 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 BWK49_RS19665 d1761b11d15662ddc606e8ff18a7b391 300 PIRSF PIRSF001365 9 299 7.7E-88 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 BWK49_RS19665 d1761b11d15662ddc606e8ff18a7b391 300 SMART SM01130 11 297 5.5E-117 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 BWK49_RS19665 d1761b11d15662ddc606e8ff18a7b391 300 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 11 295 55.818 T 06-07-2017 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 BWK49_RS19665 d1761b11d15662ddc606e8ff18a7b391 300 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 48 65 - T 06-07-2017 IPR020624 Schiff base-forming aldolase, conserved site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 BWK49_RS19665 d1761b11d15662ddc606e8ff18a7b391 300 Gene3D G3DSA:3.20.20.70 12 299 1.3E-102 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 BWK49_RS19665 d1761b11d15662ddc606e8ff18a7b391 300 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 143 173 - T 06-07-2017 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 BWK49_RS19665 d1761b11d15662ddc606e8ff18a7b391 300 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 15 289 1.5E-78 T 06-07-2017 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 BWK49_RS19665 d1761b11d15662ddc606e8ff18a7b391 300 PRINTS PR00146 Dihydrodipicolinate synthase signature 113 129 2.2E-29 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 BWK49_RS19665 d1761b11d15662ddc606e8ff18a7b391 300 PRINTS PR00146 Dihydrodipicolinate synthase signature 45 66 2.2E-29 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 BWK49_RS19665 d1761b11d15662ddc606e8ff18a7b391 300 PRINTS PR00146 Dihydrodipicolinate synthase signature 81 99 2.2E-29 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 BWK49_RS19665 d1761b11d15662ddc606e8ff18a7b391 300 PRINTS PR00146 Dihydrodipicolinate synthase signature 138 155 2.2E-29 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 BWK49_RS19665 d1761b11d15662ddc606e8ff18a7b391 300 SUPERFAMILY SSF51569 12 297 6.07E-92 T 06-07-2017 BWK49_RS18795 5c4f15164aa8de648c6bb8527b70a708 613 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 40 575 7.7E-140 T 06-07-2017 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 BWK49_RS18795 5c4f15164aa8de648c6bb8527b70a708 613 Pfam PF02355 Protein export membrane protein 403 577 9.0E-8 T 06-07-2017 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial BWK49_RS18795 5c4f15164aa8de648c6bb8527b70a708 613 PRINTS PR01217 Proline rich extensin signature 164 180 1.3E-9 T 06-07-2017 BWK49_RS18795 5c4f15164aa8de648c6bb8527b70a708 613 PRINTS PR01217 Proline rich extensin signature 185 202 1.3E-9 T 06-07-2017 BWK49_RS18795 5c4f15164aa8de648c6bb8527b70a708 613 PRINTS PR01217 Proline rich extensin signature 123 135 1.3E-9 T 06-07-2017 BWK49_RS18795 5c4f15164aa8de648c6bb8527b70a708 613 PRINTS PR01217 Proline rich extensin signature 135 156 1.3E-9 T 06-07-2017 BWK49_RS18795 5c4f15164aa8de648c6bb8527b70a708 613 PRINTS PR01217 Proline rich extensin signature 204 229 1.3E-9 T 06-07-2017 BWK49_RS18795 5c4f15164aa8de648c6bb8527b70a708 613 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 2 588 37.973 T 06-07-2017 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 BWK49_RS18795 5c4f15164aa8de648c6bb8527b70a708 613 Pfam PF07549 SecD/SecF GG Motif 39 57 5.4E-4 T 06-07-2017 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site BWK49_RS18795 5c4f15164aa8de648c6bb8527b70a708 613 SUPERFAMILY SSF82866 381 578 1.16E-24 T 06-07-2017 BWK49_RS18795 5c4f15164aa8de648c6bb8527b70a708 613 Gene3D G3DSA:1.20.1640.10 386 579 3.8E-18 T 06-07-2017 BWK49_RS18795 5c4f15164aa8de648c6bb8527b70a708 613 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 331 567 2.2E-71 T 06-07-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial BWK49_RS24925 a4b22d8e9f08384a2143f13bedc5219e 185 Gene3D G3DSA:1.10.357.10 8 132 1.4E-20 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS24925 a4b22d8e9f08384a2143f13bedc5219e 185 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 58 2.8E-14 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS24925 a4b22d8e9f08384a2143f13bedc5219e 185 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 2.1E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS24925 a4b22d8e9f08384a2143f13bedc5219e 185 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 2.1E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS24925 a4b22d8e9f08384a2143f13bedc5219e 185 SUPERFAMILY SSF46689 6 78 1.8E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS18450 04b451beac22da7619c4ec2daf9c164b 223 Gene3D G3DSA:3.30.63.10 59 104 6.3E-23 T 06-07-2017 BWK49_RS18450 04b451beac22da7619c4ec2daf9c164b 223 SMART SM00072 20 204 2.7E-69 T 06-07-2017 IPR008145 Guanylate kinase/L-type calcium channel beta subunit BWK49_RS18450 04b451beac22da7619c4ec2daf9c164b 223 Gene3D G3DSA:3.40.50.300 33 58 1.6E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS18450 04b451beac22da7619c4ec2daf9c164b 223 Gene3D G3DSA:3.40.50.300 105 207 4.0E-38 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS18450 04b451beac22da7619c4ec2daf9c164b 223 Gene3D G3DSA:3.40.50.300 19 32 4.0E-38 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS18450 04b451beac22da7619c4ec2daf9c164b 223 Pfam PF00625 Guanylate kinase 21 200 7.4E-38 T 06-07-2017 IPR008145 Guanylate kinase/L-type calcium channel beta subunit BWK49_RS18450 04b451beac22da7619c4ec2daf9c164b 223 Hamap MF_00328 Guanylate kinase [gmk]. 19 204 34.507 T 06-07-2017 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 BWK49_RS18450 04b451beac22da7619c4ec2daf9c164b 223 ProSitePatterns PS00856 Guanylate kinase-like signature. 55 72 - T 06-07-2017 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 BWK49_RS18450 04b451beac22da7619c4ec2daf9c164b 223 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 21 200 8.3E-63 T 06-07-2017 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 BWK49_RS18450 04b451beac22da7619c4ec2daf9c164b 223 SUPERFAMILY SSF52540 19 201 5.66E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS18930 66c6043eff6321b3cad2d30a5453ccfc 418 Gene3D G3DSA:3.30.70.360 196 312 1.2E-33 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain BWK49_RS18930 66c6043eff6321b3cad2d30a5453ccfc 418 SUPERFAMILY SSF53187 313 415 1.31E-72 T 06-07-2017 BWK49_RS18930 66c6043eff6321b3cad2d30a5453ccfc 418 SUPERFAMILY SSF53187 8 210 1.31E-72 T 06-07-2017 BWK49_RS18930 66c6043eff6321b3cad2d30a5453ccfc 418 Pfam PF01546 Peptidase family M20/M25/M40 75 366 2.0E-21 T 06-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 BWK49_RS18930 66c6043eff6321b3cad2d30a5453ccfc 418 Pfam PF07687 Peptidase dimerisation domain 198 293 1.4E-10 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain BWK49_RS18930 66c6043eff6321b3cad2d30a5453ccfc 418 SUPERFAMILY SSF55031 197 298 7.59E-26 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain BWK49_RS18930 66c6043eff6321b3cad2d30a5453ccfc 418 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 20 354 3.3E-76 T 06-07-2017 IPR017439 Amidohydrolase GO:0016787 BWK49_RS18930 66c6043eff6321b3cad2d30a5453ccfc 418 Gene3D G3DSA:3.40.630.10 313 415 6.6E-85 T 06-07-2017 BWK49_RS18930 66c6043eff6321b3cad2d30a5453ccfc 418 Gene3D G3DSA:3.40.630.10 6 191 6.6E-85 T 06-07-2017 BWK49_RS18930 66c6043eff6321b3cad2d30a5453ccfc 418 PIRSF PIRSF005962 5 377 1.7E-94 T 06-07-2017 IPR017439 Amidohydrolase GO:0016787 BWK49_RS26400 8a3712233046ef1767d1caca0ccec2ee 259 Gene3D G3DSA:1.10.150.290 179 234 2.9E-22 T 06-07-2017 IPR023149 Trans-aconitate 2-methyltransferase, C-terminal GO:0030798 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 BWK49_RS26400 8a3712233046ef1767d1caca0ccec2ee 259 SUPERFAMILY SSF53335 19 246 3.44E-31 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS26400 8a3712233046ef1767d1caca0ccec2ee 259 Gene3D G3DSA:3.40.50.150 4 151 7.9E-28 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS26400 8a3712233046ef1767d1caca0ccec2ee 259 Pfam PF13489 Methyltransferase domain 13 142 3.3E-14 T 06-07-2017 BWK49_RS26400 8a3712233046ef1767d1caca0ccec2ee 259 Hamap MF_00560 Trans-aconitate 2-methyltransferase [tam]. 1 254 43.954 T 06-07-2017 IPR023506 Trans-aconitate 2-methyltransferase GO:0030798 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 BWK49_RS10535 bbed641f8eb733bbe2ebf88d58730e83 307 Pfam PF01435 Peptidase family M48 124 206 1.1E-10 T 06-07-2017 IPR001915 Peptidase M48 GO:0004222|GO:0006508 BWK49_RS10535 bbed641f8eb733bbe2ebf88d58730e83 307 Gene3D G3DSA:3.30.2010.10 119 192 1.3E-13 T 06-07-2017 BWK49_RS24115 ef6db8b4ad6a316a0f7d79a5603c6c70 295 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 9 22 - T 06-07-2017 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 BWK49_RS24115 ef6db8b4ad6a316a0f7d79a5603c6c70 295 PIRSF PIRSF000103 1 295 5.0E-83 T 06-07-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 BWK49_RS24115 ef6db8b4ad6a316a0f7d79a5603c6c70 295 SUPERFAMILY SSF48179 164 294 9.98E-38 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 BWK49_RS24115 ef6db8b4ad6a316a0f7d79a5603c6c70 295 Gene3D G3DSA:3.40.50.720 4 162 1.6E-53 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS24115 ef6db8b4ad6a316a0f7d79a5603c6c70 295 TIGRFAM TIGR01692 HIBADH: 3-hydroxyisobutyrate dehydrogenase 9 295 7.3E-108 T 06-07-2017 IPR011548 3-hydroxyisobutyrate dehydrogenase GO:0008442|GO:0051287|GO:0055114 KEGG: 00280+1.1.1.31|Reactome: R-HSA-70895 BWK49_RS24115 ef6db8b4ad6a316a0f7d79a5603c6c70 295 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 165 293 6.0E-36 T 06-07-2017 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 BWK49_RS24115 ef6db8b4ad6a316a0f7d79a5603c6c70 295 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 7 162 1.8E-48 T 06-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 BWK49_RS24115 ef6db8b4ad6a316a0f7d79a5603c6c70 295 Gene3D G3DSA:1.10.1040.10 164 294 1.1E-42 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 BWK49_RS24115 ef6db8b4ad6a316a0f7d79a5603c6c70 295 SUPERFAMILY SSF51735 6 163 3.79E-44 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS25370 79ee20c0a714543bd067e4d867dcbd78 249 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 9 18 - T 06-07-2017 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 BWK49_RS25370 79ee20c0a714543bd067e4d867dcbd78 249 SMART SM00855 6 190 6.0E-23 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 BWK49_RS25370 79ee20c0a714543bd067e4d867dcbd78 249 SUPERFAMILY SSF53254 6 224 2.08E-70 T 06-07-2017 IPR029033 Histidine phosphatase superfamily BWK49_RS25370 79ee20c0a714543bd067e4d867dcbd78 249 Hamap MF_01039 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [gpmA]. 4 231 41.85 T 06-07-2017 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 BWK49_RS25370 79ee20c0a714543bd067e4d867dcbd78 249 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 7 130 4.2E-28 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 BWK49_RS25370 79ee20c0a714543bd067e4d867dcbd78 249 TIGRFAM TIGR01258 pgm_1: phosphoglycerate mutase 1 family 6 248 1.5E-112 T 06-07-2017 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 BWK49_RS25370 79ee20c0a714543bd067e4d867dcbd78 249 Gene3D G3DSA:3.40.50.1240 5 247 2.2E-85 T 06-07-2017 IPR029033 Histidine phosphatase superfamily BWK49_RS03390 2e23e4efa301288f80fd4290f8ecbd05 150 Gene3D G3DSA:2.30.110.10 42 105 3.5E-8 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 BWK49_RS03390 2e23e4efa301288f80fd4290f8ecbd05 150 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 37 149 3.9E-37 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 BWK49_RS03390 2e23e4efa301288f80fd4290f8ecbd05 150 SUPERFAMILY SSF50475 40 145 1.03E-11 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 BWK49_RS03390 2e23e4efa301288f80fd4290f8ecbd05 150 Pfam PF04075 Domain of unknown function (DUF385) 24 149 1.5E-49 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 BWK49_RS23060 a94abff2e6d277e52b84284857cb6db9 735 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 174 721 9.4E-171 T 06-07-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 BWK49_RS23060 a94abff2e6d277e52b84284857cb6db9 735 SUPERFAMILY SSF56784 474 718 9.9E-56 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS23060 a94abff2e6d277e52b84284857cb6db9 735 SUPERFAMILY SSF56784 415 434 9.9E-56 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS23060 a94abff2e6d277e52b84284857cb6db9 735 Gene3D G3DSA:3.40.50.1000 545 687 5.0E-46 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS23060 a94abff2e6d277e52b84284857cb6db9 735 Gene3D G3DSA:3.40.50.1000 389 430 5.0E-46 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS23060 a94abff2e6d277e52b84284857cb6db9 735 Pfam PF00122 E1-E2 ATPase 196 407 4.5E-54 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 BWK49_RS23060 a94abff2e6d277e52b84284857cb6db9 735 Gene3D G3DSA:2.70.150.10 205 324 3.6E-20 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 BWK49_RS23060 a94abff2e6d277e52b84284857cb6db9 735 SUPERFAMILY SSF81665 325 434 2.62E-5 T 06-07-2017 BWK49_RS23060 a94abff2e6d277e52b84284857cb6db9 735 SUPERFAMILY SSF81665 179 227 2.62E-5 T 06-07-2017 BWK49_RS23060 a94abff2e6d277e52b84284857cb6db9 735 SUPERFAMILY SSF81653 229 323 1.57E-21 T 06-07-2017 BWK49_RS23060 a94abff2e6d277e52b84284857cb6db9 735 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 590 606 4.9E-5 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 BWK49_RS23060 a94abff2e6d277e52b84284857cb6db9 735 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 618 634 4.9E-5 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 BWK49_RS23060 a94abff2e6d277e52b84284857cb6db9 735 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 155 721 1.5E-125 T 06-07-2017 BWK49_RS23060 a94abff2e6d277e52b84284857cb6db9 735 Pfam PF00702 haloacid dehalogenase-like hydrolase 412 632 1.4E-44 T 06-07-2017 BWK49_RS23060 a94abff2e6d277e52b84284857cb6db9 735 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 416 430 5.4E-26 T 06-07-2017 BWK49_RS23060 a94abff2e6d277e52b84284857cb6db9 735 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 542 553 5.4E-26 T 06-07-2017 BWK49_RS23060 a94abff2e6d277e52b84284857cb6db9 735 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 642 654 5.4E-26 T 06-07-2017 BWK49_RS23060 a94abff2e6d277e52b84284857cb6db9 735 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 274 288 5.4E-26 T 06-07-2017 BWK49_RS23060 a94abff2e6d277e52b84284857cb6db9 735 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 565 575 5.4E-26 T 06-07-2017 BWK49_RS23060 a94abff2e6d277e52b84284857cb6db9 735 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 618 637 5.4E-26 T 06-07-2017 BWK49_RS23060 a94abff2e6d277e52b84284857cb6db9 735 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 197 699 3.4E-74 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 BWK49_RS23060 a94abff2e6d277e52b84284857cb6db9 735 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 418 424 - T 06-07-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 BWK49_RS23060 a94abff2e6d277e52b84284857cb6db9 735 Gene3D G3DSA:3.40.1110.10 431 544 1.4E-21 T 06-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 BWK49_RS19820 f16b3d80231bad9dcbe66dcc1c4e06dd 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 22.141 T 06-07-2017 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS19820 f16b3d80231bad9dcbe66dcc1c4e06dd 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 10 88 4.0E-26 T 06-07-2017 BWK49_RS19820 f16b3d80231bad9dcbe66dcc1c4e06dd 89 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 06-07-2017 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS19820 f16b3d80231bad9dcbe66dcc1c4e06dd 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 5 89 2.4E-39 T 06-07-2017 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS19820 f16b3d80231bad9dcbe66dcc1c4e06dd 89 SMART SM01387 8 88 2.6E-48 T 06-07-2017 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS19820 f16b3d80231bad9dcbe66dcc1c4e06dd 89 Pfam PF00312 Ribosomal protein S15 8 88 1.4E-35 T 06-07-2017 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS19820 f16b3d80231bad9dcbe66dcc1c4e06dd 89 SUPERFAMILY SSF47060 3 89 2.94E-34 T 06-07-2017 IPR009068 S15/NS1, RNA-binding BWK49_RS19820 f16b3d80231bad9dcbe66dcc1c4e06dd 89 Gene3D G3DSA:1.10.287.10 3 89 4.1E-37 T 06-07-2017 IPR009068 S15/NS1, RNA-binding BWK49_RS20445 b5d2130b1e1b0e505cce6a3ce2b44065 206 Pfam PF02720 Domain of unknown function (DUF222) 19 172 2.2E-35 T 06-07-2017 IPR003870 Domain of unknown function DUF222 BWK49_RS16170 85398afa5e6fa7f5759d3028a15b40ca 381 SUPERFAMILY SSF53686 35 344 4.06E-73 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme BWK49_RS16170 85398afa5e6fa7f5759d3028a15b40ca 381 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 40 322 1.4E-53 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme BWK49_RS16170 85398afa5e6fa7f5759d3028a15b40ca 381 Gene3D G3DSA:3.40.50.1100 72 177 1.1E-26 T 06-07-2017 BWK49_RS16170 85398afa5e6fa7f5759d3028a15b40ca 381 Gene3D G3DSA:3.40.50.1100 35 71 1.7E-37 T 06-07-2017 BWK49_RS16170 85398afa5e6fa7f5759d3028a15b40ca 381 Gene3D G3DSA:3.40.50.1100 183 341 1.7E-37 T 06-07-2017 BWK49_RS16170 85398afa5e6fa7f5759d3028a15b40ca 381 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 62 80 - T 06-07-2017 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 BWK49_RS19565 5ce8bdf500eb068719af29db23a98399 512 SMART SM00729 160 384 2.6E-57 T 06-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 BWK49_RS19565 5ce8bdf500eb068719af29db23a98399 512 Pfam PF04055 Radical SAM superfamily 164 341 3.4E-29 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 BWK49_RS19565 5ce8bdf500eb068719af29db23a98399 512 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 18 464 3.0E-150 T 06-07-2017 IPR005839 Methylthiotransferase GO:0016740|GO:0043412|GO:0051539 BWK49_RS19565 5ce8bdf500eb068719af29db23a98399 512 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 17 470 68.24 T 06-07-2017 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 BWK49_RS19565 5ce8bdf500eb068719af29db23a98399 512 SUPERFAMILY SSF102114 147 391 1.2E-58 T 06-07-2017 BWK49_RS19565 5ce8bdf500eb068719af29db23a98399 512 Pfam PF00919 Uncharacterized protein family UPF0004 19 117 1.3E-29 T 06-07-2017 IPR013848 Methylthiotransferase, N-terminal GO:0003824|GO:0009451|GO:0051539 BWK49_RS19565 5ce8bdf500eb068719af29db23a98399 512 Gene3D G3DSA:3.80.30.20 160 395 9.4E-81 T 06-07-2017 IPR023404 Radical SAM, alpha/beta horseshoe BWK49_RS19565 5ce8bdf500eb068719af29db23a98399 512 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 19 433 1.5E-139 T 06-07-2017 BWK49_RS19565 5ce8bdf500eb068719af29db23a98399 512 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 164 184 - T 06-07-2017 IPR020612 Methylthiotransferase, conserved site GO:0051539 BWK49_RS25480 6857ed1b0c956786470c57f4ec6e5023 428 Gene3D G3DSA:3.20.20.60 11 409 3.1E-159 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 BWK49_RS25480 6857ed1b0c956786470c57f4ec6e5023 428 TIGRFAM TIGR01346 isocit_lyase: isocitrate lyase 252 427 3.4E-86 T 06-07-2017 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 BWK49_RS25480 6857ed1b0c956786470c57f4ec6e5023 428 TIGRFAM TIGR01346 isocit_lyase: isocitrate lyase 11 251 1.1E-108 T 06-07-2017 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 BWK49_RS25480 6857ed1b0c956786470c57f4ec6e5023 428 SUPERFAMILY SSF51621 8 427 8.97E-156 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 BWK49_RS25480 6857ed1b0c956786470c57f4ec6e5023 428 PIRSF PIRSF001362 3 428 1.2E-232 T 06-07-2017 BWK49_RS25480 6857ed1b0c956786470c57f4ec6e5023 428 Pfam PF00463 Isocitrate lyase family 252 426 3.4E-47 T 06-07-2017 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 BWK49_RS25480 6857ed1b0c956786470c57f4ec6e5023 428 Pfam PF00463 Isocitrate lyase family 11 251 5.7E-53 T 06-07-2017 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 BWK49_RS25480 6857ed1b0c956786470c57f4ec6e5023 428 ProSitePatterns PS00161 Isocitrate lyase signature. 189 194 - T 06-07-2017 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824|GO:0008152 BWK49_RS18390 d30e1c004cf69b1458c0c9104397da71 275 Gene3D G3DSA:3.40.50.150 35 174 1.3E-32 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS18390 d30e1c004cf69b1458c0c9104397da71 275 Gene3D G3DSA:3.40.50.150 209 272 1.3E-32 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS18390 d30e1c004cf69b1458c0c9104397da71 275 SUPERFAMILY SSF53335 25 175 3.98E-33 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS18390 d30e1c004cf69b1458c0c9104397da71 275 Pfam PF08241 Methyltransferase domain 53 146 4.1E-19 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 BWK49_RS13180 7f9dc7fa5e2dd74be25da8b5837a55a3 250 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 199 4.5E-45 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 BWK49_RS13180 7f9dc7fa5e2dd74be25da8b5837a55a3 250 TIGRFAM TIGR03848 MSMEG_4193: probable phosphomutase, MSMEG_4193 family 2 204 1.6E-100 T 06-07-2017 IPR022492 Phosphomutase MSMEG4193, putative BWK49_RS13180 7f9dc7fa5e2dd74be25da8b5837a55a3 250 Gene3D G3DSA:3.40.50.1240 1 201 1.1E-42 T 06-07-2017 IPR029033 Histidine phosphatase superfamily BWK49_RS13180 7f9dc7fa5e2dd74be25da8b5837a55a3 250 SMART SM00855 2 160 3.7E-21 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 BWK49_RS13180 7f9dc7fa5e2dd74be25da8b5837a55a3 250 SUPERFAMILY SSF53254 1 201 2.36E-42 T 06-07-2017 IPR029033 Histidine phosphatase superfamily BWK49_RS12910 e90165a32147e3e65b3509ec89bdd60e 382 SUPERFAMILY SSF47648 39 105 5.63E-16 T 06-07-2017 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 BWK49_RS12910 e90165a32147e3e65b3509ec89bdd60e 382 SUPERFAMILY SSF52418 112 380 1.44E-80 T 06-07-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 BWK49_RS12910 e90165a32147e3e65b3509ec89bdd60e 382 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 41 378 34.362 T 06-07-2017 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 BWK49_RS12910 e90165a32147e3e65b3509ec89bdd60e 382 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 44 377 6.3E-116 T 06-07-2017 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 BWK49_RS12910 e90165a32147e3e65b3509ec89bdd60e 382 Pfam PF00591 Glycosyl transferase family, a/b domain 113 368 2.7E-90 T 06-07-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 BWK49_RS12910 e90165a32147e3e65b3509ec89bdd60e 382 Gene3D G3DSA:3.40.1030.10 112 380 5.6E-102 T 06-07-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 BWK49_RS12910 e90165a32147e3e65b3509ec89bdd60e 382 Pfam PF02885 Glycosyl transferase family, helical bundle domain 43 102 1.4E-14 T 06-07-2017 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 BWK49_RS12910 e90165a32147e3e65b3509ec89bdd60e 382 Gene3D G3DSA:1.20.970.10 38 102 6.0E-21 T 06-07-2017 BWK49_RS03825 e796dd42b185c3fc0f14020c619cc703 144 SUPERFAMILY SSF69118 3 112 6.24E-17 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 BWK49_RS03825 e796dd42b185c3fc0f14020c619cc703 144 Pfam PF02627 Carboxymuconolactone decarboxylase family 28 101 3.1E-6 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 BWK49_RS03825 e796dd42b185c3fc0f14020c619cc703 144 Gene3D G3DSA:1.20.1290.10 5 125 1.5E-9 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 BWK49_RS14960 954800886aba7bc0d59d12a5a8fe34dd 258 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 43 252 5.8E-34 T 06-07-2017 IPR005950 Molybdenum ABC transporter, periplasmic binding protein GO:0015412|GO:0015689|GO:0030288 BWK49_RS14960 954800886aba7bc0d59d12a5a8fe34dd 258 PIRSF PIRSF004846 2 258 6.3E-61 T 06-07-2017 IPR005950 Molybdenum ABC transporter, periplasmic binding protein GO:0015412|GO:0015689|GO:0030288 BWK49_RS14960 954800886aba7bc0d59d12a5a8fe34dd 258 SUPERFAMILY SSF53850 37 257 3.54E-53 T 06-07-2017 BWK49_RS14960 954800886aba7bc0d59d12a5a8fe34dd 258 Pfam PF13531 Bacterial extracellular solute-binding protein 40 255 1.6E-42 T 06-07-2017 BWK49_RS14960 954800886aba7bc0d59d12a5a8fe34dd 258 Gene3D G3DSA:3.40.190.10 34 164 2.3E-34 T 06-07-2017 BWK49_RS14960 954800886aba7bc0d59d12a5a8fe34dd 258 Gene3D G3DSA:3.40.190.10 177 247 4.6E-9 T 06-07-2017 BWK49_RS14710 72a07a06a4497236c4368dbab6514790 428 SUPERFAMILY SSF48264 11 414 8.77E-79 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS14710 72a07a06a4497236c4368dbab6514790 428 Pfam PF00067 Cytochrome P450 295 383 1.4E-12 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS14710 72a07a06a4497236c4368dbab6514790 428 Gene3D G3DSA:1.10.630.10 12 416 1.8E-107 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS14710 72a07a06a4497236c4368dbab6514790 428 PRINTS PR00359 B-class P450 signature 213 235 4.0E-43 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS14710 72a07a06a4497236c4368dbab6514790 428 PRINTS PR00359 B-class P450 signature 110 121 4.0E-43 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS14710 72a07a06a4497236c4368dbab6514790 428 PRINTS PR00359 B-class P450 signature 368 379 4.0E-43 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS14710 72a07a06a4497236c4368dbab6514790 428 PRINTS PR00359 B-class P450 signature 156 172 4.0E-43 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS14710 72a07a06a4497236c4368dbab6514790 428 PRINTS PR00359 B-class P450 signature 292 303 4.0E-43 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS14710 72a07a06a4497236c4368dbab6514790 428 PRINTS PR00359 B-class P450 signature 309 336 4.0E-43 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS14710 72a07a06a4497236c4368dbab6514790 428 PRINTS PR00359 B-class P450 signature 359 368 4.0E-43 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS14710 72a07a06a4497236c4368dbab6514790 428 PRINTS PR00359 B-class P450 signature 337 352 4.0E-43 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS14710 72a07a06a4497236c4368dbab6514790 428 PRINTS PR00359 B-class P450 signature 173 188 4.0E-43 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS06950 a0e83457c842ff03afb48102f4feb265 554 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 498 515 - T 06-07-2017 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 BWK49_RS06950 a0e83457c842ff03afb48102f4feb265 554 ProSitePatterns PS00765 Phosphoglucose isomerase signature 1. 268 281 - T 06-07-2017 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 BWK49_RS06950 a0e83457c842ff03afb48102f4feb265 554 Gene3D G3DSA:1.10.1390.10 512 552 3.2E-18 T 06-07-2017 IPR023096 Phosphoglucose isomerase, C-terminal GO:0004347|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 BWK49_RS06950 a0e83457c842ff03afb48102f4feb265 554 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 49 525 41.56 T 06-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 BWK49_RS06950 a0e83457c842ff03afb48102f4feb265 554 SUPERFAMILY SSF53697 9 550 9.73E-203 T 06-07-2017 BWK49_RS06950 a0e83457c842ff03afb48102f4feb265 554 Gene3D G3DSA:3.40.50.10490 150 188 1.3E-153 T 06-07-2017 BWK49_RS06950 a0e83457c842ff03afb48102f4feb265 554 Gene3D G3DSA:3.40.50.10490 266 502 1.3E-153 T 06-07-2017 BWK49_RS06950 a0e83457c842ff03afb48102f4feb265 554 Gene3D G3DSA:3.40.50.10490 9 105 1.3E-153 T 06-07-2017 BWK49_RS06950 a0e83457c842ff03afb48102f4feb265 554 Pfam PF00342 Phosphoglucose isomerase 55 543 5.8E-204 T 06-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 BWK49_RS06950 a0e83457c842ff03afb48102f4feb265 554 PRINTS PR00662 Glucose-6-phosphate isomerase signature 484 498 1.4E-55 T 06-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 BWK49_RS06950 a0e83457c842ff03afb48102f4feb265 554 PRINTS PR00662 Glucose-6-phosphate isomerase signature 264 282 1.4E-55 T 06-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 BWK49_RS06950 a0e83457c842ff03afb48102f4feb265 554 PRINTS PR00662 Glucose-6-phosphate isomerase signature 466 484 1.4E-55 T 06-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 BWK49_RS06950 a0e83457c842ff03afb48102f4feb265 554 PRINTS PR00662 Glucose-6-phosphate isomerase signature 498 511 1.4E-55 T 06-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 BWK49_RS06950 a0e83457c842ff03afb48102f4feb265 554 PRINTS PR00662 Glucose-6-phosphate isomerase signature 341 362 1.4E-55 T 06-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 BWK49_RS06950 a0e83457c842ff03afb48102f4feb265 554 PRINTS PR00662 Glucose-6-phosphate isomerase signature 153 172 1.4E-55 T 06-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 BWK49_RS12005 cd67fb3ac88f07c06dc8c8be29ba7a4f 339 Gene3D G3DSA:3.20.20.30 7 332 6.5E-40 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS12005 cd67fb3ac88f07c06dc8c8be29ba7a4f 339 TIGRFAM TIGR03617 F420_MSMEG_2256: probable F420-dependent oxidoreductase, MSMEG_2256 family 19 322 1.7E-91 T 06-07-2017 IPR019919 Luciferase-like, F420-dependent oxidoreductase, MSMEG2256, predicted BWK49_RS12005 cd67fb3ac88f07c06dc8c8be29ba7a4f 339 Pfam PF00296 Luciferase-like monooxygenase 7 308 3.2E-55 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS12005 cd67fb3ac88f07c06dc8c8be29ba7a4f 339 SUPERFAMILY SSF51679 9 329 3.79E-44 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS00080 84579f209faea89a71fce8f37062f6da 176 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 60 77 - T 06-07-2017 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 BWK49_RS00080 84579f209faea89a71fce8f37062f6da 176 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 11 174 1.7E-47 T 06-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 BWK49_RS00080 84579f209faea89a71fce8f37062f6da 176 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 120 132 1.9E-25 T 06-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 BWK49_RS00080 84579f209faea89a71fce8f37062f6da 176 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 65 77 1.9E-25 T 06-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 BWK49_RS00080 84579f209faea89a71fce8f37062f6da 176 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 133 148 1.9E-25 T 06-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 BWK49_RS00080 84579f209faea89a71fce8f37062f6da 176 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 24 39 1.9E-25 T 06-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 BWK49_RS00080 84579f209faea89a71fce8f37062f6da 176 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 105 120 1.9E-25 T 06-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 BWK49_RS00080 84579f209faea89a71fce8f37062f6da 176 PIRSF PIRSF001467 1 176 9.9E-60 T 06-07-2017 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755|GO:0006457 BWK49_RS00080 84579f209faea89a71fce8f37062f6da 176 Gene3D G3DSA:2.40.100.10 5 175 3.2E-64 T 06-07-2017 IPR029000 Cyclophilin-like domain BWK49_RS00080 84579f209faea89a71fce8f37062f6da 176 SUPERFAMILY SSF50891 10 175 3.36E-62 T 06-07-2017 IPR029000 Cyclophilin-like domain BWK49_RS16755 2557100a15850db1b7ec7dc07663f1b4 372 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 34 129 1.6E-11 T 06-07-2017 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain BWK49_RS16755 2557100a15850db1b7ec7dc07663f1b4 372 SUPERFAMILY SSF51604 117 371 6.68E-65 T 06-07-2017 IPR029065 Enolase C-terminal domain-like BWK49_RS16755 2557100a15850db1b7ec7dc07663f1b4 372 SUPERFAMILY SSF54826 10 129 5.56E-27 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 BWK49_RS16755 2557100a15850db1b7ec7dc07663f1b4 372 Gene3D G3DSA:3.20.20.120 134 371 1.8E-63 T 06-07-2017 IPR029065 Enolase C-terminal domain-like BWK49_RS16755 2557100a15850db1b7ec7dc07663f1b4 372 Gene3D G3DSA:3.30.390.10 8 133 1.1E-32 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 BWK49_RS16755 2557100a15850db1b7ec7dc07663f1b4 372 Pfam PF13378 Enolase C-terminal domain-like 152 362 1.0E-61 T 06-07-2017 IPR029065 Enolase C-terminal domain-like BWK49_RS16755 2557100a15850db1b7ec7dc07663f1b4 372 SMART SM00922 148 249 1.6E-21 T 06-07-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal BWK49_RS16755 2557100a15850db1b7ec7dc07663f1b4 372 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 104 129 - T 06-07-2017 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 BWK49_RS27035 1c8ebb85acd5bb1a9b01fc9b8516939c 361 Pfam PF00990 Diguanylate cyclase, GGDEF domain 202 356 9.7E-35 T 06-07-2017 IPR000160 GGDEF domain BWK49_RS27035 1c8ebb85acd5bb1a9b01fc9b8516939c 361 SUPERFAMILY SSF55073 206 357 3.69E-35 T 06-07-2017 IPR029787 Nucleotide cyclase BWK49_RS27035 1c8ebb85acd5bb1a9b01fc9b8516939c 361 SUPERFAMILY SSF55781 42 182 5.67E-22 T 06-07-2017 IPR029016 GAF domain-like BWK49_RS27035 1c8ebb85acd5bb1a9b01fc9b8516939c 361 SMART SM00065 38 180 8.8E-9 T 06-07-2017 IPR003018 GAF domain GO:0005515 BWK49_RS27035 1c8ebb85acd5bb1a9b01fc9b8516939c 361 Gene3D G3DSA:3.30.70.270 203 356 1.5E-38 T 06-07-2017 BWK49_RS27035 1c8ebb85acd5bb1a9b01fc9b8516939c 361 Gene3D G3DSA:3.30.450.40 24 184 1.8E-20 T 06-07-2017 IPR029016 GAF domain-like BWK49_RS27035 1c8ebb85acd5bb1a9b01fc9b8516939c 361 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 199 356 7.4E-33 T 06-07-2017 IPR000160 GGDEF domain BWK49_RS27035 1c8ebb85acd5bb1a9b01fc9b8516939c 361 SMART SM00267 190 360 2.1E-37 T 06-07-2017 IPR000160 GGDEF domain BWK49_RS27035 1c8ebb85acd5bb1a9b01fc9b8516939c 361 Pfam PF13185 GAF domain 36 171 3.7E-11 T 06-07-2017 IPR003018 GAF domain GO:0005515 BWK49_RS15495 03ada3a938ae6523ff455f6a00dd5b84 407 Gene3D G3DSA:1.10.630.10 17 407 5.4E-110 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS15495 03ada3a938ae6523ff455f6a00dd5b84 407 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 349 358 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 BWK49_RS15495 03ada3a938ae6523ff455f6a00dd5b84 407 PRINTS PR00359 B-class P450 signature 161 176 1.7E-52 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS15495 03ada3a938ae6523ff455f6a00dd5b84 407 PRINTS PR00359 B-class P450 signature 97 108 1.7E-52 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS15495 03ada3a938ae6523ff455f6a00dd5b84 407 PRINTS PR00359 B-class P450 signature 144 160 1.7E-52 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS15495 03ada3a938ae6523ff455f6a00dd5b84 407 PRINTS PR00359 B-class P450 signature 326 341 1.7E-52 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS15495 03ada3a938ae6523ff455f6a00dd5b84 407 PRINTS PR00359 B-class P450 signature 280 291 1.7E-52 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS15495 03ada3a938ae6523ff455f6a00dd5b84 407 PRINTS PR00359 B-class P450 signature 356 367 1.7E-52 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS15495 03ada3a938ae6523ff455f6a00dd5b84 407 PRINTS PR00359 B-class P450 signature 198 220 1.7E-52 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS15495 03ada3a938ae6523ff455f6a00dd5b84 407 PRINTS PR00359 B-class P450 signature 298 325 1.7E-52 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS15495 03ada3a938ae6523ff455f6a00dd5b84 407 PRINTS PR00359 B-class P450 signature 347 356 1.7E-52 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS15495 03ada3a938ae6523ff455f6a00dd5b84 407 Pfam PF00067 Cytochrome P450 280 376 3.4E-18 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS15495 03ada3a938ae6523ff455f6a00dd5b84 407 PRINTS PR00385 P450 superfamily signature 243 260 7.3E-9 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS15495 03ada3a938ae6523ff455f6a00dd5b84 407 PRINTS PR00385 P450 superfamily signature 280 291 7.3E-9 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS15495 03ada3a938ae6523ff455f6a00dd5b84 407 PRINTS PR00385 P450 superfamily signature 356 367 7.3E-9 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS15495 03ada3a938ae6523ff455f6a00dd5b84 407 PRINTS PR00385 P450 superfamily signature 347 356 7.3E-9 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS15495 03ada3a938ae6523ff455f6a00dd5b84 407 SUPERFAMILY SSF48264 22 407 1.31E-84 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS20635 e130494ebe4c5c24ad62dff943d4a3cf 406 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 325 401 1.4E-16 T 06-07-2017 IPR022171 PPE family, C-terminal BWK49_RS20635 e130494ebe4c5c24ad62dff943d4a3cf 406 SUPERFAMILY SSF140459 6 178 3.4E-63 T 06-07-2017 BWK49_RS20635 e130494ebe4c5c24ad62dff943d4a3cf 406 Pfam PF00823 PPE family 9 165 1.7E-62 T 06-07-2017 IPR000030 PPE family BWK49_RS07975 8c6e09f23961d247dc45d53a7a4b5c69 340 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 186 214 1.9E-9 T 06-07-2017 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 BWK49_RS07975 8c6e09f23961d247dc45d53a7a4b5c69 340 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 155 2.4E-42 T 06-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 BWK49_RS07975 8c6e09f23961d247dc45d53a7a4b5c69 340 TIGRFAM TIGR00872 gnd_rel: 6-phosphogluconate dehydrogenase (decarboxylating) 1 340 3.0E-153 T 06-07-2017 IPR004849 6-phosphogluconate dehydrogenase, YqeC-type GO:0055114 BWK49_RS07975 8c6e09f23961d247dc45d53a7a4b5c69 340 SUPERFAMILY SSF51735 1 161 1.27E-48 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS07975 8c6e09f23961d247dc45d53a7a4b5c69 340 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 1 24 4.2E-19 T 06-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 BWK49_RS07975 8c6e09f23961d247dc45d53a7a4b5c69 340 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 60 89 4.2E-19 T 06-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 BWK49_RS07975 8c6e09f23961d247dc45d53a7a4b5c69 340 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 113 138 4.2E-19 T 06-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 BWK49_RS07975 8c6e09f23961d247dc45d53a7a4b5c69 340 Gene3D G3DSA:1.10.1040.10 188 331 3.0E-33 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 BWK49_RS07975 8c6e09f23961d247dc45d53a7a4b5c69 340 Gene3D G3DSA:3.40.50.720 1 187 1.9E-49 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS07975 8c6e09f23961d247dc45d53a7a4b5c69 340 SMART SM01350 186 335 5.4E-5 T 06-07-2017 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 BWK49_RS07975 8c6e09f23961d247dc45d53a7a4b5c69 340 SUPERFAMILY SSF48179 184 334 8.84E-36 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 BWK49_RS00395 dc260dc50866934656a5375251919853 1028 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 948 970 3.3E-7 T 06-07-2017 IPR030934 Intein C-terminal splicing region BWK49_RS00395 dc260dc50866934656a5375251919853 1028 Pfam PF03796 DnaB-like helicase C terminal domain 377 1025 2.0E-78 T 06-07-2017 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 BWK49_RS00395 dc260dc50866934656a5375251919853 1028 Pfam PF03796 DnaB-like helicase C terminal domain 201 233 3.0E-9 T 06-07-2017 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 BWK49_RS00395 dc260dc50866934656a5375251919853 1028 Gene3D G3DSA:3.10.28.10 745 853 6.3E-23 T 06-07-2017 IPR027434 Homing endonuclease GO:0004519 BWK49_RS00395 dc260dc50866934656a5375251919853 1028 PRINTS PR00379 Intein signature 608 621 7.4E-21 T 06-07-2017 IPR006142 Intein GO:0016539 BWK49_RS00395 dc260dc50866934656a5375251919853 1028 PRINTS PR00379 Intein signature 793 808 7.4E-21 T 06-07-2017 IPR006142 Intein GO:0016539 BWK49_RS00395 dc260dc50866934656a5375251919853 1028 PRINTS PR00379 Intein signature 946 963 7.4E-21 T 06-07-2017 IPR006142 Intein GO:0016539 BWK49_RS00395 dc260dc50866934656a5375251919853 1028 PRINTS PR00379 Intein signature 964 973 7.4E-21 T 06-07-2017 IPR006142 Intein GO:0016539 BWK49_RS00395 dc260dc50866934656a5375251919853 1028 PRINTS PR00379 Intein signature 656 668 7.4E-21 T 06-07-2017 IPR006142 Intein GO:0016539 BWK49_RS00395 dc260dc50866934656a5375251919853 1028 PRINTS PR00379 Intein signature 761 773 7.4E-21 T 06-07-2017 IPR006142 Intein GO:0016539 BWK49_RS00395 dc260dc50866934656a5375251919853 1028 SMART SM00305 930 975 2.5E-13 T 06-07-2017 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 BWK49_RS00395 dc260dc50866934656a5375251919853 1028 Pfam PF00772 DnaB-like helicase N terminal domain 23 125 2.8E-33 T 06-07-2017 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 BWK49_RS00395 dc260dc50866934656a5375251919853 1028 SUPERFAMILY SSF52540 378 548 3.39E-24 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS00395 dc260dc50866934656a5375251919853 1028 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 545 620 3.5E-11 T 06-07-2017 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 BWK49_RS00395 dc260dc50866934656a5375251919853 1028 Pfam PF14890 Intein splicing domain 556 969 9.5E-31 T 06-07-2017 BWK49_RS00395 dc260dc50866934656a5375251919853 1028 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 24 1027 6.9E-152 T 06-07-2017 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 BWK49_RS00395 dc260dc50866934656a5375251919853 1028 SUPERFAMILY SSF48024 22 133 3.01E-37 T 06-07-2017 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 BWK49_RS00395 dc260dc50866934656a5375251919853 1028 SMART SM00306 543 641 1.6E-21 T 06-07-2017 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 BWK49_RS00395 dc260dc50866934656a5375251919853 1028 SMART SM00306 231 321 1.8E-6 T 06-07-2017 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 BWK49_RS00395 dc260dc50866934656a5375251919853 1028 SUPERFAMILY SSF51294 905 969 2.35E-44 T 06-07-2017 IPR028992 Hedgehog/Intein (Hint) domain BWK49_RS00395 dc260dc50866934656a5375251919853 1028 SUPERFAMILY SSF51294 544 667 2.35E-44 T 06-07-2017 IPR028992 Hedgehog/Intein (Hint) domain BWK49_RS00395 dc260dc50866934656a5375251919853 1028 Gene3D G3DSA:1.10.860.10 24 126 2.1E-38 T 06-07-2017 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal BWK49_RS00395 dc260dc50866934656a5375251919853 1028 SUPERFAMILY SSF55608 747 845 7.37E-15 T 06-07-2017 IPR027434 Homing endonuclease GO:0004519 BWK49_RS00395 dc260dc50866934656a5375251919853 1028 SUPERFAMILY SSF51294 238 371 5.18E-6 T 06-07-2017 IPR028992 Hedgehog/Intein (Hint) domain BWK49_RS00395 dc260dc50866934656a5375251919853 1028 Gene3D G3DSA:2.170.16.10 925 969 6.2E-44 T 06-07-2017 IPR028992 Hedgehog/Intein (Hint) domain BWK49_RS00395 dc260dc50866934656a5375251919853 1028 Gene3D G3DSA:2.170.16.10 545 667 6.2E-44 T 06-07-2017 IPR028992 Hedgehog/Intein (Hint) domain BWK49_RS00395 dc260dc50866934656a5375251919853 1028 SUPERFAMILY SSF52540 196 232 1.02E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS00395 dc260dc50866934656a5375251919853 1028 Gene3D G3DSA:2.170.16.10 236 378 1.2E-8 T 06-07-2017 IPR028992 Hedgehog/Intein (Hint) domain BWK49_RS00395 dc260dc50866934656a5375251919853 1028 Gene3D G3DSA:3.40.50.300 185 235 8.4E-110 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS00395 dc260dc50866934656a5375251919853 1028 Gene3D G3DSA:3.40.50.300 385 544 8.4E-110 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS00395 dc260dc50866934656a5375251919853 1028 Gene3D G3DSA:3.40.50.300 970 1027 8.4E-110 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS00395 dc260dc50866934656a5375251919853 1028 Pfam PF14528 LAGLIDADG-like domain 761 840 2.2E-15 T 06-07-2017 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 BWK49_RS09465 bff658090d134d04bf6c4dd1e5bed6de 318 Pfam PF07859 alpha/beta hydrolase fold 89 291 1.5E-52 T 06-07-2017 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 BWK49_RS09465 bff658090d134d04bf6c4dd1e5bed6de 318 SUPERFAMILY SSF53474 68 316 3.82E-54 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS09465 bff658090d134d04bf6c4dd1e5bed6de 318 Gene3D G3DSA:3.40.50.1820 12 313 6.9E-71 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS11375 c3da71c1edf587ad562f701d79a28a26 1015 SMART SM00823 Phosphopantetheine attachment site 912 984 2.1E-13 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS11375 c3da71c1edf587ad562f701d79a28a26 1015 Gene3D G3DSA:3.30.70.250 226 276 7.6E-8 T 06-07-2017 BWK49_RS11375 c3da71c1edf587ad562f701d79a28a26 1015 ProSitePatterns PS00012 Phosphopantetheine attachment site. 939 954 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site BWK49_RS11375 c3da71c1edf587ad562f701d79a28a26 1015 Pfam PF08659 KR domain 660 830 4.8E-32 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS11375 c3da71c1edf587ad562f701d79a28a26 1015 SUPERFAMILY SSF52151 288 385 5.23E-47 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 BWK49_RS11375 c3da71c1edf587ad562f701d79a28a26 1015 SUPERFAMILY SSF52151 97 224 5.23E-47 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 BWK49_RS11375 c3da71c1edf587ad562f701d79a28a26 1015 Gene3D G3DSA:3.40.366.10 286 394 1.9E-50 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 BWK49_RS11375 c3da71c1edf587ad562f701d79a28a26 1015 Gene3D G3DSA:3.40.366.10 91 218 1.9E-50 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 BWK49_RS11375 c3da71c1edf587ad562f701d79a28a26 1015 Pfam PF00550 Phosphopantetheine attachment site 914 980 4.7E-9 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS11375 c3da71c1edf587ad562f701d79a28a26 1015 Gene3D G3DSA:3.40.50.720 659 861 3.9E-27 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS11375 c3da71c1edf587ad562f701d79a28a26 1015 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 657 832 5.5E-12 T 06-07-2017 BWK49_RS11375 c3da71c1edf587ad562f701d79a28a26 1015 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 101 393 4.2E-62 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain BWK49_RS11375 c3da71c1edf587ad562f701d79a28a26 1015 SUPERFAMILY SSF51735 659 867 2.54E-35 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS11375 c3da71c1edf587ad562f701d79a28a26 1015 SUPERFAMILY SSF47336 910 996 9.95E-13 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS11375 c3da71c1edf587ad562f701d79a28a26 1015 SUPERFAMILY SSF51735 462 626 1.15E-9 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS11375 c3da71c1edf587ad562f701d79a28a26 1015 Gene3D G3DSA:1.10.1200.10 903 983 5.4E-10 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS11375 c3da71c1edf587ad562f701d79a28a26 1015 Pfam PF00698 Acyl transferase domain 100 379 2.0E-47 T 06-07-2017 IPR014043 Acyl transferase BWK49_RS11375 c3da71c1edf587ad562f701d79a28a26 1015 SUPERFAMILY SSF55048 224 287 1.06E-11 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 BWK49_RS03935 387429dd8c651d727364aa20e73cebd2 224 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 4 205 1.4E-36 T 06-07-2017 BWK49_RS03935 387429dd8c651d727364aa20e73cebd2 224 SMART SM01211 2 221 1.8E-117 T 06-07-2017 BWK49_RS03935 387429dd8c651d727364aa20e73cebd2 224 PIRSF PIRSF001586 1 223 1.6E-76 T 06-07-2017 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 BWK49_RS03935 387429dd8c651d727364aa20e73cebd2 224 Hamap MF_00421 Phosphoribosylformylglycinamidine synthase subunit PurQ [purQ]. 3 219 38.467 T 06-07-2017 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 BWK49_RS03935 387429dd8c651d727364aa20e73cebd2 224 TIGRFAM TIGR01737 FGAM_synth_I: phosphoribosylformylglycinamidine synthase I 4 219 5.5E-79 T 06-07-2017 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 BWK49_RS03935 387429dd8c651d727364aa20e73cebd2 224 Gene3D G3DSA:3.40.50.880 2 218 8.8E-39 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like BWK49_RS03935 387429dd8c651d727364aa20e73cebd2 224 SUPERFAMILY SSF52317 3 218 3.15E-68 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like BWK49_RS13705 7edc91b36c1bf51ed56bbdf5db06e2cf 360 PRINTS PR00385 P450 superfamily signature 197 214 1.0E-7 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS13705 7edc91b36c1bf51ed56bbdf5db06e2cf 360 PRINTS PR00385 P450 superfamily signature 310 321 1.0E-7 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS13705 7edc91b36c1bf51ed56bbdf5db06e2cf 360 PRINTS PR00385 P450 superfamily signature 301 310 1.0E-7 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS13705 7edc91b36c1bf51ed56bbdf5db06e2cf 360 PRINTS PR00385 P450 superfamily signature 234 245 1.0E-7 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS13705 7edc91b36c1bf51ed56bbdf5db06e2cf 360 Pfam PF00067 Cytochrome P450 155 330 7.6E-26 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS13705 7edc91b36c1bf51ed56bbdf5db06e2cf 360 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 303 312 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 BWK49_RS13705 7edc91b36c1bf51ed56bbdf5db06e2cf 360 SUPERFAMILY SSF48264 2 360 2.36E-89 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS13705 7edc91b36c1bf51ed56bbdf5db06e2cf 360 PRINTS PR00359 B-class P450 signature 50 61 3.6E-53 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS13705 7edc91b36c1bf51ed56bbdf5db06e2cf 360 PRINTS PR00359 B-class P450 signature 114 129 3.6E-53 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS13705 7edc91b36c1bf51ed56bbdf5db06e2cf 360 PRINTS PR00359 B-class P450 signature 252 279 3.6E-53 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS13705 7edc91b36c1bf51ed56bbdf5db06e2cf 360 PRINTS PR00359 B-class P450 signature 280 295 3.6E-53 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS13705 7edc91b36c1bf51ed56bbdf5db06e2cf 360 PRINTS PR00359 B-class P450 signature 151 173 3.6E-53 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS13705 7edc91b36c1bf51ed56bbdf5db06e2cf 360 PRINTS PR00359 B-class P450 signature 97 113 3.6E-53 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS13705 7edc91b36c1bf51ed56bbdf5db06e2cf 360 PRINTS PR00359 B-class P450 signature 301 310 3.6E-53 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS13705 7edc91b36c1bf51ed56bbdf5db06e2cf 360 PRINTS PR00359 B-class P450 signature 234 245 3.6E-53 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS13705 7edc91b36c1bf51ed56bbdf5db06e2cf 360 PRINTS PR00359 B-class P450 signature 310 321 3.6E-53 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS13705 7edc91b36c1bf51ed56bbdf5db06e2cf 360 Gene3D G3DSA:1.10.630.10 2 360 9.6E-109 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS26755 7d55afc75ebcd3a81d49778dae5c2cfd 334 SMART SM00062 46 270 2.1E-5 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF BWK49_RS26755 7d55afc75ebcd3a81d49778dae5c2cfd 334 SUPERFAMILY SSF53850 45 263 1.7E-43 T 06-07-2017 BWK49_RS26755 7d55afc75ebcd3a81d49778dae5c2cfd 334 Gene3D G3DSA:3.40.190.10 128 214 1.5E-26 T 06-07-2017 BWK49_RS26755 7d55afc75ebcd3a81d49778dae5c2cfd 334 TIGRFAM TIGR01728 SsuA_fam: ABC transporter, substrate-binding protein, aliphatic sulfonates family 47 327 8.6E-54 T 06-07-2017 IPR010067 Aliphatic sulfonates-binding protein GO:0006790|GO:0006810|GO:0016020 BWK49_RS26755 7d55afc75ebcd3a81d49778dae5c2cfd 334 Pfam PF09084 NMT1/THI5 like 86 261 3.7E-16 T 06-07-2017 IPR015168 SsuA/THI5-like BWK49_RS10155 37e2c8db2a05ac91a5c18ce0a403ed25 501 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 234 401 1.6E-14 T 06-07-2017 IPR004477 ComEC/Rec2-related protein BWK49_RS10155 37e2c8db2a05ac91a5c18ce0a403ed25 501 Pfam PF03772 Competence protein 212 476 2.5E-50 T 06-07-2017 IPR004477 ComEC/Rec2-related protein BWK49_RS07645 55f1f4ea0644696d5b6e87aa0b70f0d2 354 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 11 97 1.0E-5 T 06-07-2017 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 BWK49_RS07645 55f1f4ea0644696d5b6e87aa0b70f0d2 354 Gene3D G3DSA:3.40.50.720 7 134 1.5E-17 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS07645 55f1f4ea0644696d5b6e87aa0b70f0d2 354 SUPERFAMILY SSF51735 5 131 9.63E-12 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS26970 c6a0d4675ed3dd3fd6f87377a7d83e50 258 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 99 119 - T 06-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 BWK49_RS26970 c6a0d4675ed3dd3fd6f87377a7d83e50 258 SUPERFAMILY SSF52096 7 257 1.46E-76 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS26970 c6a0d4675ed3dd3fd6f87377a7d83e50 258 Pfam PF00378 Enoyl-CoA hydratase/isomerase 15 257 2.0E-50 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 BWK49_RS26970 c6a0d4675ed3dd3fd6f87377a7d83e50 258 Gene3D G3DSA:1.10.12.10 202 257 3.9E-19 T 06-07-2017 IPR014748 Crontonase, C-terminal BWK49_RS26970 c6a0d4675ed3dd3fd6f87377a7d83e50 258 Gene3D G3DSA:3.90.226.10 6 198 2.7E-59 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS07845 5dcb2e4d87b0b257070e3e5ebf93d9ca 423 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 4 90 3.8E-7 T 06-07-2017 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 BWK49_RS07845 5dcb2e4d87b0b257070e3e5ebf93d9ca 423 Gene3D G3DSA:3.40.50.2000 261 393 3.1E-6 T 06-07-2017 BWK49_RS07845 5dcb2e4d87b0b257070e3e5ebf93d9ca 423 Gene3D G3DSA:3.40.50.2000 1 260 4.8E-59 T 06-07-2017 BWK49_RS07845 5dcb2e4d87b0b257070e3e5ebf93d9ca 423 SUPERFAMILY SSF53756 1 419 1.93E-86 T 06-07-2017 BWK49_RS00955 40065ac083f9b2aadd18f14e02cc5365 408 Gene3D G3DSA:3.30.70.270 66 163 1.3E-28 T 06-07-2017 BWK49_RS00955 40065ac083f9b2aadd18f14e02cc5365 408 Gene3D G3DSA:1.10.150.20 165 235 3.2E-23 T 06-07-2017 BWK49_RS00955 40065ac083f9b2aadd18f14e02cc5365 408 SUPERFAMILY SSF56672 7 235 2.22E-77 T 06-07-2017 BWK49_RS00955 40065ac083f9b2aadd18f14e02cc5365 408 Pfam PF11798 IMS family HHH motif 168 197 1.8E-8 T 06-07-2017 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 BWK49_RS00955 40065ac083f9b2aadd18f14e02cc5365 408 Pfam PF11799 impB/mucB/samB family C-terminal domain 241 352 2.8E-14 T 06-07-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 BWK49_RS00955 40065ac083f9b2aadd18f14e02cc5365 408 SUPERFAMILY SSF100879 241 343 8.01E-18 T 06-07-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 BWK49_RS00955 40065ac083f9b2aadd18f14e02cc5365 408 Gene3D G3DSA:3.30.1490.100 240 356 5.2E-19 T 06-07-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 BWK49_RS00955 40065ac083f9b2aadd18f14e02cc5365 408 Pfam PF00817 impB/mucB/samB family 13 154 4.8E-47 T 06-07-2017 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 BWK49_RS00955 40065ac083f9b2aadd18f14e02cc5365 408 Hamap MF_01113 DNA polymerase IV [dinB]. 6 355 33.147 T 06-07-2017 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 BWK49_RS17825 ed9b4e5733b2a606e10ff1ae31e7b05b 243 SUPERFAMILY SSF46894 146 238 3.97E-24 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 BWK49_RS17825 ed9b4e5733b2a606e10ff1ae31e7b05b 243 Gene3D G3DSA:3.40.50.2300 22 142 1.8E-33 T 06-07-2017 BWK49_RS17825 ed9b4e5733b2a606e10ff1ae31e7b05b 243 SMART SM00448 23 133 2.2E-32 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 BWK49_RS17825 ed9b4e5733b2a606e10ff1ae31e7b05b 243 SMART SM00862 165 238 1.2E-24 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 BWK49_RS17825 ed9b4e5733b2a606e10ff1ae31e7b05b 243 Pfam PF00072 Response regulator receiver domain 25 133 2.6E-23 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 BWK49_RS17825 ed9b4e5733b2a606e10ff1ae31e7b05b 243 SUPERFAMILY SSF52172 20 148 4.13E-36 T 06-07-2017 IPR011006 CheY-like superfamily BWK49_RS17825 ed9b4e5733b2a606e10ff1ae31e7b05b 243 Gene3D G3DSA:1.10.10.10 144 240 4.7E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS17825 ed9b4e5733b2a606e10ff1ae31e7b05b 243 Pfam PF00486 Transcriptional regulatory protein, C terminal 166 238 4.4E-22 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 BWK49_RS07890 7c569047b933cdf45f30779b5e13f8bd 357 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 1.9E-34 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 BWK49_RS07890 7c569047b933cdf45f30779b5e13f8bd 357 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 1.9E-34 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 BWK49_RS07890 7c569047b933cdf45f30779b5e13f8bd 357 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 1.9E-34 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 BWK49_RS07890 7c569047b933cdf45f30779b5e13f8bd 357 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 1.9E-34 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 BWK49_RS07890 7c569047b933cdf45f30779b5e13f8bd 357 Pfam PF01926 50S ribosome-binding GTPase 5 115 2.6E-22 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 BWK49_RS07890 7c569047b933cdf45f30779b5e13f8bd 357 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 3 357 1.3E-129 T 06-07-2017 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 BWK49_RS07890 7c569047b933cdf45f30779b5e13f8bd 357 Pfam PF06071 Protein of unknown function (DUF933) 273 356 1.9E-38 T 06-07-2017 IPR013029 Domain of unknown function DUF933 BWK49_RS07890 7c569047b933cdf45f30779b5e13f8bd 357 SUPERFAMILY SSF52540 4 295 1.36E-72 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS07890 7c569047b933cdf45f30779b5e13f8bd 357 Gene3D G3DSA:1.10.150.300 131 196 5.5E-18 T 06-07-2017 IPR023192 TGS-like domain BWK49_RS07890 7c569047b933cdf45f30779b5e13f8bd 357 PIRSF PIRSF006641 1 357 3.1E-138 T 06-07-2017 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 BWK49_RS07890 7c569047b933cdf45f30779b5e13f8bd 357 Gene3D G3DSA:3.40.50.300 197 259 1.8E-42 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS07890 7c569047b933cdf45f30779b5e13f8bd 357 Gene3D G3DSA:3.40.50.300 4 130 1.8E-42 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS07890 7c569047b933cdf45f30779b5e13f8bd 357 SUPERFAMILY SSF81271 273 357 1.85E-34 T 06-07-2017 IPR012676 TGS-like KEGG: 00970+6.1.1.3 BWK49_RS07890 7c569047b933cdf45f30779b5e13f8bd 357 Gene3D G3DSA:3.10.20.30 260 357 5.4E-46 T 06-07-2017 IPR012675 Beta-grasp domain BWK49_RS07890 7c569047b933cdf45f30779b5e13f8bd 357 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 357 42.698 T 06-07-2017 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 BWK49_RS03420 1b6d7b75f11e076c655123975a38ed90 320 SUPERFAMILY SSF54637 23 188 1.65E-20 T 06-07-2017 IPR029069 HotDog domain BWK49_RS03420 1b6d7b75f11e076c655123975a38ed90 320 Pfam PF13452 N-terminal half of MaoC dehydratase 21 156 3.0E-18 T 06-07-2017 BWK49_RS03420 1b6d7b75f11e076c655123975a38ed90 320 SUPERFAMILY SSF50249 183 301 6.51E-22 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS03420 1b6d7b75f11e076c655123975a38ed90 320 Gene3D G3DSA:3.10.129.10 22 162 1.7E-15 T 06-07-2017 IPR029069 HotDog domain BWK49_RS03420 1b6d7b75f11e076c655123975a38ed90 320 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 237 295 6.2E-19 T 06-07-2017 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal BWK49_RS01945 ea3e2099cf9ebc95e033ffc43a5a1d82 227 ProSitePatterns PS01273 Coenzyme A transferases signature 1. 18 33 - T 06-07-2017 IPR004163 Coenzyme A transferase binding site GO:0008152|GO:0008410 BWK49_RS01945 ea3e2099cf9ebc95e033ffc43a5a1d82 227 Pfam PF01144 Coenzyme A transferase 11 217 2.4E-65 T 06-07-2017 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 BWK49_RS01945 ea3e2099cf9ebc95e033ffc43a5a1d82 227 TIGRFAM TIGR02429 pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit 7 217 2.1E-103 T 06-07-2017 IPR012792 3-oxoacid CoA-transferase, subunit A GO:0008410 BWK49_RS01945 ea3e2099cf9ebc95e033ffc43a5a1d82 227 Gene3D G3DSA:3.40.1080.10 8 217 3.9E-83 T 06-07-2017 BWK49_RS01945 ea3e2099cf9ebc95e033ffc43a5a1d82 227 SUPERFAMILY SSF100950 9 220 2.44E-73 T 06-07-2017 BWK49_RS01945 ea3e2099cf9ebc95e033ffc43a5a1d82 227 SMART SM00882 6 219 1.4E-73 T 06-07-2017 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 BWK49_RS23875 d842c0f14abe9fb10429628a886345f7 473 Gene3D G3DSA:3.40.50.10260 2 218 3.9E-51 T 06-07-2017 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 BWK49_RS23875 d842c0f14abe9fb10429628a886345f7 473 SUPERFAMILY SSF53613 213 470 2.55E-59 T 06-07-2017 IPR029056 Ribokinase-like BWK49_RS23875 d842c0f14abe9fb10429628a886345f7 473 SUPERFAMILY SSF64153 3 231 3.66E-45 T 06-07-2017 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 BWK49_RS23875 d842c0f14abe9fb10429628a886345f7 473 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 408 418 - T 06-07-2017 IPR017953 Carbohydrate kinase, predicted, conserved site BWK49_RS23875 d842c0f14abe9fb10429628a886345f7 473 PIRSF PIRSF017184 3 473 2.0E-91 T 06-07-2017 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 BWK49_RS23875 d842c0f14abe9fb10429628a886345f7 473 ProSitePatterns PS01049 YjeF C-terminal domain signature 1. 292 302 - T 06-07-2017 IPR017953 Carbohydrate kinase, predicted, conserved site BWK49_RS23875 d842c0f14abe9fb10429628a886345f7 473 Pfam PF01256 Carbohydrate kinase 234 464 1.1E-68 T 06-07-2017 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 BWK49_RS23875 d842c0f14abe9fb10429628a886345f7 473 Pfam PF03853 YjeF-related protein N-terminus 25 182 7.0E-35 T 06-07-2017 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 BWK49_RS23875 d842c0f14abe9fb10429628a886345f7 473 Gene3D G3DSA:3.40.1190.20 219 471 3.2E-80 T 06-07-2017 IPR029056 Ribokinase-like BWK49_RS23875 d842c0f14abe9fb10429628a886345f7 473 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 210 472 19.468 T 06-07-2017 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 BWK49_RS23875 d842c0f14abe9fb10429628a886345f7 473 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 225 449 2.1E-40 T 06-07-2017 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 BWK49_RS23875 d842c0f14abe9fb10429628a886345f7 473 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 4 200 19.044 T 06-07-2017 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 BWK49_RS20575 0136fb35051abf4ef3576e7235604f35 608 Gene3D G3DSA:3.30.420.10 130 296 8.3E-41 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS20575 0136fb35051abf4ef3576e7235604f35 608 Gene3D G3DSA:1.10.10.10 12 54 1.4E-4 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS20575 0136fb35051abf4ef3576e7235604f35 608 SUPERFAMILY SSF53098 133 298 7.33E-36 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS20575 0136fb35051abf4ef3576e7235604f35 608 SUPERFAMILY SSF46689 7 115 2.33E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS20575 0136fb35051abf4ef3576e7235604f35 608 Pfam PF13565 Homeodomain-like domain 39 111 1.4E-16 T 06-07-2017 BWK49_RS20575 0136fb35051abf4ef3576e7235604f35 608 Pfam PF00665 Integrase core domain 134 257 6.1E-24 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 BWK49_RS17545 0db75d9a230dbc3e3f848c8fd2313051 346 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 192 200 7.2E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS17545 0db75d9a230dbc3e3f848c8fd2313051 346 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 212 231 7.2E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS17545 0db75d9a230dbc3e3f848c8fd2313051 346 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 148 7.2E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS17545 0db75d9a230dbc3e3f848c8fd2313051 346 SUPERFAMILY SSF51735 60 279 4.16E-61 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS17545 0db75d9a230dbc3e3f848c8fd2313051 346 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 62 236 9.8E-4 T 06-07-2017 BWK49_RS17545 0db75d9a230dbc3e3f848c8fd2313051 346 Gene3D G3DSA:3.40.50.720 61 292 6.9E-62 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS17545 0db75d9a230dbc3e3f848c8fd2313051 346 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 137 148 1.9E-21 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS17545 0db75d9a230dbc3e3f848c8fd2313051 346 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 233 250 1.9E-21 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS17545 0db75d9a230dbc3e3f848c8fd2313051 346 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 231 1.9E-21 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS17545 0db75d9a230dbc3e3f848c8fd2313051 346 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 63 80 1.9E-21 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS17545 0db75d9a230dbc3e3f848c8fd2313051 346 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 186 202 1.9E-21 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS17545 0db75d9a230dbc3e3f848c8fd2313051 346 Pfam PF00106 short chain dehydrogenase 62 251 1.9E-48 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS18025 df94b4f81c0a9b512697ef56e34a9890 129 Gene3D G3DSA:3.30.1330.40 9 128 4.0E-27 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like BWK49_RS18025 df94b4f81c0a9b512697ef56e34a9890 129 SUPERFAMILY SSF55298 2 128 5.97E-25 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like BWK49_RS18025 df94b4f81c0a9b512697ef56e34a9890 129 Pfam PF01042 Endoribonuclease L-PSP 15 126 5.5E-15 T 06-07-2017 IPR006175 YjgF/YER057c/UK114 family BWK49_RS21095 d342945468f4a6901613f3ec8ab42fa4 526 SUPERFAMILY SSF88713 10 405 5.17E-94 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 BWK49_RS21095 d342945468f4a6901613f3ec8ab42fa4 526 Pfam PF03065 Glycosyl hydrolase family 57 151 280 7.5E-15 T 06-07-2017 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 BWK49_RS21095 d342945468f4a6901613f3ec8ab42fa4 526 Gene3D G3DSA:3.20.110.10 9 405 3.8E-117 T 06-07-2017 IPR027291 Glycoside hydrolase 38/57, N-terminal domain BWK49_RS21095 d342945468f4a6901613f3ec8ab42fa4 526 Gene3D G3DSA:1.20.1430.10 425 522 4.8E-12 T 06-07-2017 IPR015293 Domain of unknown function DUF1957 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 BWK49_RS21095 d342945468f4a6901613f3ec8ab42fa4 526 Pfam PF09210 Domain of unknown function (DUF1957) 444 522 9.0E-20 T 06-07-2017 IPR015293 Domain of unknown function DUF1957 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 BWK49_RS21095 d342945468f4a6901613f3ec8ab42fa4 526 SUPERFAMILY SSF88688 400 525 2.81E-21 T 06-07-2017 IPR028995 Glycoside hydrolase families 57/38, central domain BWK49_RS14080 d84f23d72d3f7891997e4db8aff8dfc5 302 TIGRFAM TIGR02957 SigX4: RNA polymerase sigma-70 factor, TIGR02957 family 7 288 3.6E-101 T 06-07-2017 IPR014303 RNA polymerase sigma-70, ECF type BWK49_RS14080 d84f23d72d3f7891997e4db8aff8dfc5 302 Gene3D G3DSA:3.10.450.50 168 287 7.3E-17 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS14080 d84f23d72d3f7891997e4db8aff8dfc5 302 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 8 160 5.2E-18 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS14080 d84f23d72d3f7891997e4db8aff8dfc5 302 SUPERFAMILY SSF88659 80 165 4.86E-13 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS14080 d84f23d72d3f7891997e4db8aff8dfc5 302 SUPERFAMILY SSF88946 8 87 1.06E-14 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS14080 d84f23d72d3f7891997e4db8aff8dfc5 302 Pfam PF04542 Sigma-70 region 2 9 71 1.1E-13 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS14080 d84f23d72d3f7891997e4db8aff8dfc5 302 Gene3D G3DSA:1.10.10.10 107 159 9.8E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS14080 d84f23d72d3f7891997e4db8aff8dfc5 302 Pfam PF08281 Sigma-70, region 4 108 159 2.0E-11 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS14080 d84f23d72d3f7891997e4db8aff8dfc5 302 Gene3D G3DSA:1.10.1740.10 8 73 6.0E-15 T 06-07-2017 BWK49_RS14080 d84f23d72d3f7891997e4db8aff8dfc5 302 SUPERFAMILY SSF54427 168 286 1.31E-15 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS22705 636334fdee22763b7ec1a8ce2fb4f29d 509 SUPERFAMILY SSF52540 85 372 4.64E-72 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS22705 636334fdee22763b7ec1a8ce2fb4f29d 509 Pfam PF00270 DEAD/DEAH box helicase 35 208 6.3E-48 T 06-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 BWK49_RS22705 636334fdee22763b7ec1a8ce2fb4f29d 509 SMART SM00490 276 357 1.0E-33 T 06-07-2017 IPR001650 Helicase, C-terminal BWK49_RS22705 636334fdee22763b7ec1a8ce2fb4f29d 509 Pfam PF00271 Helicase conserved C-terminal domain 248 357 6.4E-29 T 06-07-2017 IPR001650 Helicase, C-terminal BWK49_RS22705 636334fdee22763b7ec1a8ce2fb4f29d 509 SMART SM00487 29 240 4.8E-49 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain BWK49_RS22705 636334fdee22763b7ec1a8ce2fb4f29d 509 Gene3D G3DSA:3.40.50.300 234 386 2.6E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS22705 636334fdee22763b7ec1a8ce2fb4f29d 509 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 169 177 - T 06-07-2017 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site BWK49_RS22705 636334fdee22763b7ec1a8ce2fb4f29d 509 Gene3D G3DSA:3.40.50.300 9 233 3.3E-71 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS03050 b75b1f0aa7234211e7a223c6fd80a326 810 Gene3D G3DSA:3.40.50.300 155 340 3.0E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS03050 b75b1f0aa7234211e7a223c6fd80a326 810 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 115 602 3.5E-228 T 06-07-2017 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 BWK49_RS03050 b75b1f0aa7234211e7a223c6fd80a326 810 SMART SM00382 195 334 8.9E-26 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS03050 b75b1f0aa7234211e7a223c6fd80a326 810 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 5 610 36.064 T 06-07-2017 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 BWK49_RS03050 b75b1f0aa7234211e7a223c6fd80a326 810 SUPERFAMILY SSF52540 155 403 3.54E-71 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS03050 b75b1f0aa7234211e7a223c6fd80a326 810 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 199 330 1.3E-45 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 BWK49_RS03050 b75b1f0aa7234211e7a223c6fd80a326 810 Pfam PF01434 Peptidase family M41 393 601 1.2E-78 T 06-07-2017 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 BWK49_RS03050 b75b1f0aa7234211e7a223c6fd80a326 810 SUPERFAMILY SSF140990 413 607 1.44E-67 T 06-07-2017 BWK49_RS03050 b75b1f0aa7234211e7a223c6fd80a326 810 Gene3D G3DSA:1.10.8.60 341 406 4.0E-21 T 06-07-2017 BWK49_RS03050 b75b1f0aa7234211e7a223c6fd80a326 810 ProSitePatterns PS00674 AAA-protein family signature. 302 320 - T 06-07-2017 IPR003960 ATPase, AAA-type, conserved site GO:0005524 BWK49_RS03970 83a559737f72f6e75f088f93343ab525 235 Gene3D G3DSA:1.10.150.240 28 82 3.0E-5 T 06-07-2017 IPR023198 Phosphoglycolate phosphatase, domain 2 BWK49_RS03970 83a559737f72f6e75f088f93343ab525 235 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 182 195 5.8E-13 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 BWK49_RS03970 83a559737f72f6e75f088f93343ab525 235 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 105 118 5.8E-13 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 BWK49_RS03970 83a559737f72f6e75f088f93343ab525 235 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 137 153 5.8E-13 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 BWK49_RS03970 83a559737f72f6e75f088f93343ab525 235 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 4 15 5.8E-13 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 BWK49_RS03970 83a559737f72f6e75f088f93343ab525 235 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 155 175 5.8E-13 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 BWK49_RS03970 83a559737f72f6e75f088f93343ab525 235 TIGRFAM TIGR01428 HAD_type_II: haloacid dehalogenase, type II 5 199 5.9E-54 T 06-07-2017 IPR006328 Haloacid dehalogenase, type II GO:0008152|GO:0019120 KEGG: 00361+3.8.1.2|KEGG: 00625+3.8.1.2|MetaCyc: PWY-7425 BWK49_RS03970 83a559737f72f6e75f088f93343ab525 235 SUPERFAMILY SSF56784 2 219 1.24E-41 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS03970 83a559737f72f6e75f088f93343ab525 235 TIGRFAM TIGR01493 HAD-SF-IA-v2: HAD hydrolase, family IA, variant 2 7 184 6.2E-18 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 BWK49_RS03970 83a559737f72f6e75f088f93343ab525 235 Gene3D G3DSA:3.40.50.1000 83 221 1.5E-28 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS03970 83a559737f72f6e75f088f93343ab525 235 Pfam PF00702 haloacid dehalogenase-like hydrolase 66 186 2.8E-13 T 06-07-2017 BWK49_RS00310 68cadeda76574898b68711c7d6043313 201 SUPERFAMILY SSF46689 14 71 1.7E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS00310 68cadeda76574898b68711c7d6043313 201 Gene3D G3DSA:1.10.10.60 13 61 1.0E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS00310 68cadeda76574898b68711c7d6043313 201 Gene3D G3DSA:1.10.357.10 62 195 1.4E-7 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS00310 68cadeda76574898b68711c7d6043313 201 SUPERFAMILY SSF48498 84 198 4.0E-5 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS00310 68cadeda76574898b68711c7d6043313 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 68 1.3E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS23015 abb50a0a3ad09a08cddffae1dd061b02 456 Hamap MF_01259 Coenzyme F420:L-glutamate ligase [fbiB]. 25 456 56.803 T 06-07-2017 IPR023661 Coenzyme F420:L-glutamate ligase, bacteria GO:0043773|GO:0046872|GO:0051188 KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 BWK49_RS23015 abb50a0a3ad09a08cddffae1dd061b02 456 Gene3D G3DSA:3.40.109.10 267 448 1.0E-36 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 BWK49_RS23015 abb50a0a3ad09a08cddffae1dd061b02 456 SUPERFAMILY SSF144010 21 255 2.35E-66 T 06-07-2017 BWK49_RS23015 abb50a0a3ad09a08cddffae1dd061b02 456 Gene3D G3DSA:3.90.1660.10 79 141 2.5E-19 T 06-07-2017 BWK49_RS23015 abb50a0a3ad09a08cddffae1dd061b02 456 Pfam PF00881 Nitroreductase family 268 436 6.1E-27 T 06-07-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 BWK49_RS23015 abb50a0a3ad09a08cddffae1dd061b02 456 TIGRFAM TIGR03553 F420_FbiB_CTERM: F420 biosynthesis protein FbiB, C-terminal domain 263 456 1.1E-102 T 06-07-2017 IPR019943 Coenzyme F420 biosynthesis protein FbiB, C-terminal GO:0016881 KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 BWK49_RS23015 abb50a0a3ad09a08cddffae1dd061b02 456 SUPERFAMILY SSF55469 263 451 2.22E-37 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 BWK49_RS23015 abb50a0a3ad09a08cddffae1dd061b02 456 Gene3D G3DSA:3.30.1330.100 19 67 1.4E-54 T 06-07-2017 BWK49_RS23015 abb50a0a3ad09a08cddffae1dd061b02 456 Gene3D G3DSA:3.30.1330.100 142 230 1.4E-54 T 06-07-2017 BWK49_RS23015 abb50a0a3ad09a08cddffae1dd061b02 456 TIGRFAM TIGR01916 F420_cofE: coenzyme F420-0:L-glutamate ligase 20 250 6.1E-81 T 06-07-2017 IPR008225 Coenzyme F420:L-glutamate ligase GO:0043773|GO:0046872|GO:0051188 KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 BWK49_RS23015 abb50a0a3ad09a08cddffae1dd061b02 456 Pfam PF01996 F420-0:Gamma-glutamyl ligase 28 69 4.0E-6 T 06-07-2017 IPR002847 Coenzyme F420:L-glutamate ligase-like domain KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 BWK49_RS23015 abb50a0a3ad09a08cddffae1dd061b02 456 Pfam PF01996 F420-0:Gamma-glutamyl ligase 98 227 2.3E-31 T 06-07-2017 IPR002847 Coenzyme F420:L-glutamate ligase-like domain KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 BWK49_RS21935 4b9ae115f400f6f7034ae2cb8d2b111f 323 Gene3D G3DSA:3.90.180.10 1 142 2.1E-34 T 06-07-2017 IPR011032 GroES-like BWK49_RS21935 4b9ae115f400f6f7034ae2cb8d2b111f 323 SUPERFAMILY SSF51735 109 267 6.27E-40 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS21935 4b9ae115f400f6f7034ae2cb8d2b111f 323 Pfam PF00107 Zinc-binding dehydrogenase 149 263 2.1E-27 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 BWK49_RS21935 4b9ae115f400f6f7034ae2cb8d2b111f 323 SMART SM00829 7 319 5.5E-37 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 BWK49_RS21935 4b9ae115f400f6f7034ae2cb8d2b111f 323 SUPERFAMILY SSF50129 1 138 1.43E-31 T 06-07-2017 IPR011032 GroES-like BWK49_RS21935 4b9ae115f400f6f7034ae2cb8d2b111f 323 Gene3D G3DSA:3.40.50.720 143 259 7.9E-31 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS21935 4b9ae115f400f6f7034ae2cb8d2b111f 323 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 86 4.1E-6 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 BWK49_RS26540 efebf1814dc093e8628476862840c0fc 216 Gene3D G3DSA:1.10.357.10 71 211 2.1E-15 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS26540 efebf1814dc093e8628476862840c0fc 216 SUPERFAMILY SSF48498 94 210 8.56E-29 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS26540 efebf1814dc093e8628476862840c0fc 216 SUPERFAMILY SSF46689 18 93 1.4E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS26540 efebf1814dc093e8628476862840c0fc 216 Gene3D G3DSA:1.10.10.60 19 70 1.6E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS26540 efebf1814dc093e8628476862840c0fc 216 Pfam PF00440 Bacterial regulatory proteins, tetR family 32 73 9.8E-12 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS25685 9ffd939feb302204a5c96206809a03a1 187 SUPERFAMILY SSF55961 35 161 1.85E-5 T 06-07-2017 BWK49_RS11220 c8a5c45de5f785b6b8dd10756dee2433 248 Gene3D G3DSA:3.10.20.30 6 103 2.6E-27 T 06-07-2017 IPR012675 Beta-grasp domain BWK49_RS11220 c8a5c45de5f785b6b8dd10756dee2433 248 Pfam PF13183 4Fe-4S dicluster domain 140 216 7.1E-14 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain BWK49_RS11220 c8a5c45de5f785b6b8dd10756dee2433 248 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 53 61 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 BWK49_RS11220 c8a5c45de5f785b6b8dd10756dee2433 248 SUPERFAMILY SSF46548 124 229 6.28E-18 T 06-07-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 BWK49_RS11220 c8a5c45de5f785b6b8dd10756dee2433 248 SUPERFAMILY SSF54292 6 103 2.16E-21 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 BWK49_RS11220 c8a5c45de5f785b6b8dd10756dee2433 248 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 7 105 2.0E-25 T 06-07-2017 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 BWK49_RS11220 c8a5c45de5f785b6b8dd10756dee2433 248 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 17 223 4.8E-41 T 06-07-2017 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 BWK49_RS11220 c8a5c45de5f785b6b8dd10756dee2433 248 Gene3D G3DSA:1.10.1060.10 108 233 2.8E-18 T 06-07-2017 BWK49_RS07415 e9ccf76af171147443e9f9173a9d3a53 313 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 63 90 - T 06-07-2017 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 BWK49_RS07415 e9ccf76af171147443e9f9173a9d3a53 313 SMART SM00650 47 222 1.2E-68 T 06-07-2017 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 BWK49_RS07415 e9ccf76af171147443e9f9173a9d3a53 313 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 31 296 47.981 T 06-07-2017 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 BWK49_RS07415 e9ccf76af171147443e9f9173a9d3a53 313 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 31 293 2.2E-80 T 06-07-2017 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 BWK49_RS07415 e9ccf76af171147443e9f9173a9d3a53 313 Gene3D G3DSA:1.10.8.100 233 294 6.7E-19 T 06-07-2017 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201 BWK49_RS07415 e9ccf76af171147443e9f9173a9d3a53 313 SUPERFAMILY SSF53335 31 293 4.67E-60 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS07415 e9ccf76af171147443e9f9173a9d3a53 313 Pfam PF00398 Ribosomal RNA adenine dimethylase 32 292 1.4E-39 T 06-07-2017 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm BWK49_RS07415 e9ccf76af171147443e9f9173a9d3a53 313 Gene3D G3DSA:3.40.50.150 18 221 1.1E-64 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS15615 107424510d9cfb08d1d1483414ca111f 537 Pfam PF00501 AMP-binding enzyme 38 431 1.2E-74 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS15615 107424510d9cfb08d1d1483414ca111f 537 Gene3D G3DSA:3.40.50.980 192 343 2.4E-33 T 06-07-2017 BWK49_RS15615 107424510d9cfb08d1d1483414ca111f 537 Pfam PF13193 AMP-binding enzyme C-terminal domain 441 516 6.7E-8 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS15615 107424510d9cfb08d1d1483414ca111f 537 SUPERFAMILY SSF56801 29 525 1.83E-114 T 06-07-2017 BWK49_RS15615 107424510d9cfb08d1d1483414ca111f 537 Gene3D G3DSA:2.30.38.10 353 422 1.5E-13 T 06-07-2017 BWK49_RS15615 107424510d9cfb08d1d1483414ca111f 537 Gene3D G3DSA:3.40.50.980 31 191 6.5E-32 T 06-07-2017 BWK49_RS15615 107424510d9cfb08d1d1483414ca111f 537 Gene3D G3DSA:3.30.300.30 427 524 2.2E-19 T 06-07-2017 BWK49_RS11370 9cb69436c65c94282cc219b714ace4da 439 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 269 385 6.1E-37 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal BWK49_RS11370 9cb69436c65c94282cc219b714ace4da 439 Gene3D G3DSA:3.40.47.10 14 273 3.9E-80 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS11370 9cb69436c65c94282cc219b714ace4da 439 SUPERFAMILY SSF53901 10 383 1.71E-84 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS11370 9cb69436c65c94282cc219b714ace4da 439 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 12 261 5.3E-78 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal BWK49_RS11370 9cb69436c65c94282cc219b714ace4da 439 Gene3D G3DSA:3.40.47.10 275 434 7.1E-51 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS11370 9cb69436c65c94282cc219b714ace4da 439 SMART SM00825 Beta-ketoacyl synthase 14 438 1.1E-142 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain BWK49_RS09050 972144cbc095bf261410d0ffc9001f8c 541 Gene3D G3DSA:3.30.70.1230 356 530 1.6E-29 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 BWK49_RS09050 972144cbc095bf261410d0ffc9001f8c 541 SUPERFAMILY SSF158472 279 326 1.19E-5 T 06-07-2017 BWK49_RS09050 972144cbc095bf261410d0ffc9001f8c 541 SMART SM00044 325 515 1.5E-6 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 BWK49_RS09050 972144cbc095bf261410d0ffc9001f8c 541 Pfam PF00672 HAMP domain 258 326 1.7E-11 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 BWK49_RS09050 972144cbc095bf261410d0ffc9001f8c 541 SMART SM00304 277 329 3.8E-10 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 BWK49_RS09050 972144cbc095bf261410d0ffc9001f8c 541 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 358 525 6.4E-20 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 BWK49_RS09050 972144cbc095bf261410d0ffc9001f8c 541 SUPERFAMILY SSF55073 352 530 7.85E-42 T 06-07-2017 IPR029787 Nucleotide cyclase BWK49_RS19435 e978aa01578c403cafc1c13c5e028e49 123 SUPERFAMILY SSF56399 11 115 7.19E-27 T 06-07-2017 BWK49_RS19435 e978aa01578c403cafc1c13c5e028e49 123 Pfam PF06108 Protein of unknown function (DUF952) 15 104 4.9E-25 T 06-07-2017 IPR009297 Protein of unknown function DUF952 BWK49_RS02140 c2f36fbafa36660b9f9f23da9d05cc1b 350 Pfam PF01636 Phosphotransferase enzyme family 33 258 9.1E-30 T 06-07-2017 IPR002575 Aminoglycoside phosphotransferase BWK49_RS02140 c2f36fbafa36660b9f9f23da9d05cc1b 350 SUPERFAMILY SSF56112 10 301 8.16E-49 T 06-07-2017 IPR011009 Protein kinase-like domain BWK49_RS02140 c2f36fbafa36660b9f9f23da9d05cc1b 350 Gene3D G3DSA:3.90.1200.10 132 304 3.2E-32 T 06-07-2017 BWK49_RS03455 536ae79b529656ac4822543e3983bcf6 310 SUPERFAMILY SSF55347 127 276 3.79E-57 T 06-07-2017 BWK49_RS03455 536ae79b529656ac4822543e3983bcf6 310 PIRSF PIRSF015689 1 307 1.7E-135 T 06-07-2017 IPR003361 Acetaldehyde dehydrogenase GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 BWK49_RS03455 536ae79b529656ac4822543e3983bcf6 310 Hamap MF_01657 Acetaldehyde dehydrogenase [mhpF]. 1 310 143.011 T 06-07-2017 IPR003361 Acetaldehyde dehydrogenase GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 BWK49_RS03455 536ae79b529656ac4822543e3983bcf6 310 TIGRFAM TIGR03215 ac_ald_DH_ac: acetaldehyde dehydrogenase (acetylating) 4 300 4.3E-134 T 06-07-2017 IPR003361 Acetaldehyde dehydrogenase GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 BWK49_RS03455 536ae79b529656ac4822543e3983bcf6 310 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 7 116 1.2E-8 T 06-07-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 BWK49_RS03455 536ae79b529656ac4822543e3983bcf6 310 Gene3D G3DSA:3.40.50.720 3 141 6.8E-68 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS03455 536ae79b529656ac4822543e3983bcf6 310 SUPERFAMILY SSF51735 1 141 1.29E-25 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS03455 536ae79b529656ac4822543e3983bcf6 310 SMART SM00859 6 119 3.8E-6 T 06-07-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 BWK49_RS03455 536ae79b529656ac4822543e3983bcf6 310 Gene3D G3DSA:3.30.360.10 142 276 4.3E-65 T 06-07-2017 BWK49_RS03455 536ae79b529656ac4822543e3983bcf6 310 Pfam PF09290 Prokaryotic acetaldehyde dehydrogenase, dimerisation 127 276 5.4E-61 T 06-07-2017 IPR015426 Acetaldehyde dehydrogenase, C-terminal GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 BWK49_RS24295 94558a0eaf9628ed67477b5fa252c2f6 274 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 209 4.4E-94 T 06-07-2017 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 BWK49_RS24295 94558a0eaf9628ed67477b5fa252c2f6 274 Gene3D G3DSA:3.30.300.20 17 106 1.0E-32 T 06-07-2017 IPR015946 K homology domain-like, alpha/beta BWK49_RS24295 94558a0eaf9628ed67477b5fa252c2f6 274 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 206 37.922 T 06-07-2017 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 BWK49_RS24295 94558a0eaf9628ed67477b5fa252c2f6 274 Pfam PF00189 Ribosomal protein S3, C-terminal domain 119 202 1.1E-36 T 06-07-2017 BWK49_RS24295 94558a0eaf9628ed67477b5fa252c2f6 274 SUPERFAMILY SSF54814 2 105 2.62E-36 T 06-07-2017 IPR009019 K homology domain, prokaryotic type GO:0003723 BWK49_RS24295 94558a0eaf9628ed67477b5fa252c2f6 274 SUPERFAMILY SSF54821 107 206 5.75E-36 T 06-07-2017 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 BWK49_RS24295 94558a0eaf9628ed67477b5fa252c2f6 274 Gene3D G3DSA:3.30.1140.32 107 206 3.0E-42 T 06-07-2017 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 BWK49_RS24295 94558a0eaf9628ed67477b5fa252c2f6 274 SMART SM00322 59 124 8.5E-8 T 06-07-2017 IPR004087 K Homology domain GO:0003676 BWK49_RS24295 94558a0eaf9628ed67477b5fa252c2f6 274 Pfam PF07650 KH domain 38 109 1.3E-18 T 06-07-2017 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 BWK49_RS24295 94558a0eaf9628ed67477b5fa252c2f6 274 ProSitePatterns PS00548 Ribosomal protein S3 signature. 163 197 - T 06-07-2017 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 BWK49_RS02745 131b9c514ea0105cc946882dfb7c8839 810 Pfam PF03793 PASTA domain 702 761 2.9E-8 T 06-07-2017 IPR005543 PASTA domain BWK49_RS02745 131b9c514ea0105cc946882dfb7c8839 810 SUPERFAMILY SSF56601 295 692 2.73E-70 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like BWK49_RS02745 131b9c514ea0105cc946882dfb7c8839 810 SUPERFAMILY SSF56601 238 260 2.73E-70 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like BWK49_RS02745 131b9c514ea0105cc946882dfb7c8839 810 SMART SM00740 697 762 2.8E-11 T 06-07-2017 IPR005543 PASTA domain BWK49_RS02745 131b9c514ea0105cc946882dfb7c8839 810 Gene3D G3DSA:3.40.710.10 258 701 7.4E-75 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like BWK49_RS02745 131b9c514ea0105cc946882dfb7c8839 810 SUPERFAMILY SSF53955 59 284 6.47E-60 T 06-07-2017 IPR023346 Lysozyme-like domain BWK49_RS02745 131b9c514ea0105cc946882dfb7c8839 810 Pfam PF00905 Penicillin binding protein transpeptidase domain 364 630 9.1E-22 T 06-07-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 BWK49_RS02745 131b9c514ea0105cc946882dfb7c8839 810 Pfam PF00912 Transglycosylase 70 256 1.0E-53 T 06-07-2017 IPR001264 Glycosyl transferase, family 51 BWK49_RS02745 131b9c514ea0105cc946882dfb7c8839 810 Gene3D G3DSA:1.10.3810.10 71 257 4.1E-61 T 06-07-2017 BWK49_RS17845 4b89873bd458ca10c8c91b1b38700179 376 SUPERFAMILY SSF117892 55 189 6.54E-39 T 06-07-2017 IPR001107 Band 7 domain BWK49_RS17845 4b89873bd458ca10c8c91b1b38700179 376 Pfam PF01145 SPFH domain / Band 7 family 29 209 5.8E-30 T 06-07-2017 IPR001107 Band 7 domain BWK49_RS17845 4b89873bd458ca10c8c91b1b38700179 376 ProSitePatterns PS01270 Band 7 protein family signature. 138 166 - T 06-07-2017 IPR018080 Band 7/stomatin-like, conserved site BWK49_RS17845 4b89873bd458ca10c8c91b1b38700179 376 SMART SM00244 24 182 4.1E-56 T 06-07-2017 IPR001107 Band 7 domain BWK49_RS17845 4b89873bd458ca10c8c91b1b38700179 376 PRINTS PR00721 Stomatin signature 79 100 2.8E-31 T 06-07-2017 IPR001972 Stomatin family GO:0016020 BWK49_RS17845 4b89873bd458ca10c8c91b1b38700179 376 PRINTS PR00721 Stomatin signature 134 157 2.8E-31 T 06-07-2017 IPR001972 Stomatin family GO:0016020 BWK49_RS17845 4b89873bd458ca10c8c91b1b38700179 376 PRINTS PR00721 Stomatin signature 31 53 2.8E-31 T 06-07-2017 IPR001972 Stomatin family GO:0016020 BWK49_RS17845 4b89873bd458ca10c8c91b1b38700179 376 PRINTS PR00721 Stomatin signature 158 176 2.8E-31 T 06-07-2017 IPR001972 Stomatin family GO:0016020 BWK49_RS17845 4b89873bd458ca10c8c91b1b38700179 376 PRINTS PR00721 Stomatin signature 177 198 2.8E-31 T 06-07-2017 IPR001972 Stomatin family GO:0016020 BWK49_RS17845 4b89873bd458ca10c8c91b1b38700179 376 PRINTS PR00721 Stomatin signature 114 131 2.8E-31 T 06-07-2017 IPR001972 Stomatin family GO:0016020 BWK49_RS18305 59859d0ecc74494b0bed139dabf0ea90 325 Pfam PF14527 WhiA LAGLIDADG-like domain 125 216 2.2E-24 T 06-07-2017 BWK49_RS18305 59859d0ecc74494b0bed139dabf0ea90 325 Pfam PF02650 WhiA C-terminal HTH domain 219 301 5.2E-20 T 06-07-2017 IPR023054 Sporulation regulator WhiA, C-terminal BWK49_RS18305 59859d0ecc74494b0bed139dabf0ea90 325 Hamap MF_01420 Putative sporulation transcription regulator WhiA [whiA]. 1 304 28.919 T 06-07-2017 IPR003802 Sporulation regulator WhiA GO:0043937 BWK49_RS18305 59859d0ecc74494b0bed139dabf0ea90 325 Pfam PF10298 WhiA N-terminal LAGLIDADG-like domain 19 102 1.1E-21 T 06-07-2017 IPR018478 Sporulation transcription regulator WhiA, N-terminal domain BWK49_RS18305 59859d0ecc74494b0bed139dabf0ea90 325 TIGRFAM TIGR00647 DNA_bind_WhiA: DNA-binding protein WhiA 2 302 3.7E-108 T 06-07-2017 BWK49_RS08705 0f30fe97e12c955d1eea624cdf8d4980 144 PRINTS PR00332 Histidine triad family signature 4 20 4.7E-15 T 06-07-2017 IPR001310 Histidine triad (HIT) protein BWK49_RS08705 0f30fe97e12c955d1eea624cdf8d4980 144 PRINTS PR00332 Histidine triad family signature 25 43 4.7E-15 T 06-07-2017 IPR001310 Histidine triad (HIT) protein BWK49_RS08705 0f30fe97e12c955d1eea624cdf8d4980 144 PRINTS PR00332 Histidine triad family signature 92 102 4.7E-15 T 06-07-2017 IPR001310 Histidine triad (HIT) protein BWK49_RS08705 0f30fe97e12c955d1eea624cdf8d4980 144 Pfam PF01230 HIT domain 11 106 9.7E-28 T 06-07-2017 IPR001310 Histidine triad (HIT) protein BWK49_RS08705 0f30fe97e12c955d1eea624cdf8d4980 144 SUPERFAMILY SSF54197 1 114 4.68E-37 T 06-07-2017 IPR011146 HIT-like domain GO:0003824 BWK49_RS08705 0f30fe97e12c955d1eea624cdf8d4980 144 ProSitePatterns PS00892 HIT domain signature. 85 103 - T 06-07-2017 IPR019808 Histidine triad, conserved site BWK49_RS08705 0f30fe97e12c955d1eea624cdf8d4980 144 Gene3D G3DSA:3.30.428.10 2 116 2.9E-38 T 06-07-2017 IPR011146 HIT-like domain GO:0003824 BWK49_RS29050 7819b8ddce4bf11337b1e355c2cee0ba 96 Gene3D G3DSA:1.10.10.60 5 40 7.8E-4 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS29050 7819b8ddce4bf11337b1e355c2cee0ba 96 Pfam PF13518 Helix-turn-helix domain 5 56 2.0E-6 T 06-07-2017 BWK49_RS20670 7819b8ddce4bf11337b1e355c2cee0ba 96 Gene3D G3DSA:1.10.10.60 5 40 7.8E-4 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS20670 7819b8ddce4bf11337b1e355c2cee0ba 96 Pfam PF13518 Helix-turn-helix domain 5 56 2.0E-6 T 06-07-2017 BWK49_RS28540 7819b8ddce4bf11337b1e355c2cee0ba 96 Gene3D G3DSA:1.10.10.60 5 40 7.8E-4 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS28540 7819b8ddce4bf11337b1e355c2cee0ba 96 Pfam PF13518 Helix-turn-helix domain 5 56 2.0E-6 T 06-07-2017 BWK49_RS09345 7819b8ddce4bf11337b1e355c2cee0ba 96 Gene3D G3DSA:1.10.10.60 5 40 7.8E-4 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS09345 7819b8ddce4bf11337b1e355c2cee0ba 96 Pfam PF13518 Helix-turn-helix domain 5 56 2.0E-6 T 06-07-2017 BWK49_RS04890 7819b8ddce4bf11337b1e355c2cee0ba 96 Gene3D G3DSA:1.10.10.60 5 40 7.8E-4 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS04890 7819b8ddce4bf11337b1e355c2cee0ba 96 Pfam PF13518 Helix-turn-helix domain 5 56 2.0E-6 T 06-07-2017 BWK49_RS16500 7819b8ddce4bf11337b1e355c2cee0ba 96 Gene3D G3DSA:1.10.10.60 5 40 7.8E-4 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS16500 7819b8ddce4bf11337b1e355c2cee0ba 96 Pfam PF13518 Helix-turn-helix domain 5 56 2.0E-6 T 06-07-2017 BWK49_RS07865 d88c3e8ea1b9e65b7033fbf77608094f 70 Gene3D G3DSA:1.10.287.1040 4 66 7.3E-21 T 06-07-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 BWK49_RS07865 d88c3e8ea1b9e65b7033fbf77608094f 70 Pfam PF02609 Exonuclease VII small subunit 9 59 7.2E-16 T 06-07-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 BWK49_RS07865 d88c3e8ea1b9e65b7033fbf77608094f 70 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 8 68 13.143 T 06-07-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 BWK49_RS07865 d88c3e8ea1b9e65b7033fbf77608094f 70 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 9 49 3.0E-15 T 06-07-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 BWK49_RS07865 d88c3e8ea1b9e65b7033fbf77608094f 70 PIRSF PIRSF006488 1 70 8.3E-25 T 06-07-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 BWK49_RS07865 d88c3e8ea1b9e65b7033fbf77608094f 70 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 9 63 5.4E-19 T 06-07-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 BWK49_RS07865 d88c3e8ea1b9e65b7033fbf77608094f 70 SUPERFAMILY SSF116842 3 63 8.76E-16 T 06-07-2017 BWK49_RS07855 a721333a34a1b2e7334d41cc480074c3 514 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 182 197 - T 06-07-2017 IPR019826 Carboxylesterase type B, active site BWK49_RS07855 a721333a34a1b2e7334d41cc480074c3 514 Gene3D G3DSA:3.40.50.1820 4 508 2.5E-144 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS07855 a721333a34a1b2e7334d41cc480074c3 514 Pfam PF00135 Carboxylesterase family 5 494 5.7E-115 T 06-07-2017 IPR002018 Carboxylesterase, type B BWK49_RS07855 a721333a34a1b2e7334d41cc480074c3 514 SUPERFAMILY SSF53474 4 511 1.61E-126 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS23020 dc8e47c71290b655193dd6bfbfae2747 532 SUPERFAMILY SSF53335 3 226 6.86E-27 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS23020 dc8e47c71290b655193dd6bfbfae2747 532 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 99 111 3.3E-17 T 06-07-2017 BWK49_RS23020 dc8e47c71290b655193dd6bfbfae2747 532 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 39 53 3.3E-17 T 06-07-2017 BWK49_RS23020 dc8e47c71290b655193dd6bfbfae2747 532 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 16 32 3.3E-17 T 06-07-2017 BWK49_RS23020 dc8e47c71290b655193dd6bfbfae2747 532 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 138 162 3.3E-17 T 06-07-2017 BWK49_RS23020 dc8e47c71290b655193dd6bfbfae2747 532 Gene3D G3DSA:3.40.50.150 18 210 8.4E-22 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS12420 288f110ba4ade8d8f1934bd0d09ac700 526 SUPERFAMILY SSF55103 279 526 2.45E-39 T 06-07-2017 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 BWK49_RS12420 288f110ba4ade8d8f1934bd0d09ac700 526 Pfam PF01565 FAD binding domain 97 236 7.2E-36 T 06-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 BWK49_RS12420 288f110ba4ade8d8f1934bd0d09ac700 526 Gene3D G3DSA:1.10.45.10 486 524 3.2E-10 T 06-07-2017 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 BWK49_RS12420 288f110ba4ade8d8f1934bd0d09ac700 526 SUPERFAMILY SSF56176 54 275 7.48E-49 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 BWK49_RS12420 288f110ba4ade8d8f1934bd0d09ac700 526 Pfam PF02913 FAD linked oxidases, C-terminal domain 275 524 1.0E-46 T 06-07-2017 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 BWK49_RS12420 288f110ba4ade8d8f1934bd0d09ac700 526 Gene3D G3DSA:3.30.465.10 157 275 5.3E-21 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 BWK49_RS12420 288f110ba4ade8d8f1934bd0d09ac700 526 Gene3D G3DSA:3.30.43.10 55 156 4.8E-19 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 BWK49_RS20460 cb92aa53269c6a7daead025e37c0b9e7 324 Gene3D G3DSA:1.10.260.40 2 38 1.4E-7 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 BWK49_RS20460 cb92aa53269c6a7daead025e37c0b9e7 324 SUPERFAMILY SSF47413 2 42 1.13E-7 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 BWK49_RS20460 cb92aa53269c6a7daead025e37c0b9e7 324 SMART SM00530 3 53 5.9E-6 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 BWK49_RS20460 cb92aa53269c6a7daead025e37c0b9e7 324 Pfam PF06114 Domain of unknown function (DUF955) 158 251 7.8E-12 T 06-07-2017 IPR010359 HTH domain, IrrE-type BWK49_RS20460 cb92aa53269c6a7daead025e37c0b9e7 324 Pfam PF01381 Helix-turn-helix 4 41 1.5E-5 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 BWK49_RS06900 e4249900919c81a13f05f08e19a369fc 647 SUPERFAMILY SSF56281 288 620 5.6E-56 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS06900 e4249900919c81a13f05f08e19a369fc 647 SUPERFAMILY SSF56529 72 303 1.83E-58 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 BWK49_RS06900 e4249900919c81a13f05f08e19a369fc 647 Pfam PF00753 Metallo-beta-lactamase superfamily 359 557 2.5E-19 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS06900 e4249900919c81a13f05f08e19a369fc 647 Gene3D G3DSA:3.60.15.10 338 437 1.1E-43 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS06900 e4249900919c81a13f05f08e19a369fc 647 Gene3D G3DSA:3.60.15.10 472 581 1.1E-43 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS06900 e4249900919c81a13f05f08e19a369fc 647 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 76 303 4.6E-50 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 BWK49_RS06900 e4249900919c81a13f05f08e19a369fc 647 SMART SM00849 358 557 2.1E-19 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS06900 e4249900919c81a13f05f08e19a369fc 647 Gene3D G3DSA:3.90.850.10 64 305 2.6E-57 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 BWK49_RS10795 827a2be80a4097b6ff7c8bcf20a82f98 380 Pfam PF13458 Periplasmic binding protein 14 343 9.2E-34 T 06-07-2017 IPR028081 Leucine-binding protein domain BWK49_RS10795 827a2be80a4097b6ff7c8bcf20a82f98 380 Gene3D G3DSA:3.40.50.2300 13 135 1.4E-14 T 06-07-2017 BWK49_RS10795 827a2be80a4097b6ff7c8bcf20a82f98 380 Gene3D G3DSA:3.40.50.2300 285 329 1.4E-14 T 06-07-2017 BWK49_RS10795 827a2be80a4097b6ff7c8bcf20a82f98 380 Gene3D G3DSA:3.40.50.2300 140 284 9.8E-14 T 06-07-2017 BWK49_RS10795 827a2be80a4097b6ff7c8bcf20a82f98 380 SUPERFAMILY SSF53822 13 339 1.18E-35 T 06-07-2017 IPR028082 Periplasmic binding protein-like I BWK49_RS21410 605b5941c2b2eb7b649237c613d92128 725 Gene3D G3DSA:2.40.110.10 464 559 6.4E-31 T 06-07-2017 BWK49_RS21410 605b5941c2b2eb7b649237c613d92128 725 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 465 558 5.3E-18 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 BWK49_RS21410 605b5941c2b2eb7b649237c613d92128 725 SUPERFAMILY SSF47203 571 720 5.15E-11 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS21410 605b5941c2b2eb7b649237c613d92128 725 Gene3D G3DSA:1.10.540.10 3 117 4.2E-23 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS21410 605b5941c2b2eb7b649237c613d92128 725 Gene3D G3DSA:1.20.140.10 205 337 4.3E-27 T 06-07-2017 BWK49_RS21410 605b5941c2b2eb7b649237c613d92128 725 SUPERFAMILY SSF47203 204 340 4.19E-29 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS21410 605b5941c2b2eb7b649237c613d92128 725 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 366 459 7.7E-7 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS21410 605b5941c2b2eb7b649237c613d92128 725 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 116 1.6E-20 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS21410 605b5941c2b2eb7b649237c613d92128 725 Gene3D G3DSA:1.20.140.10 560 722 1.8E-26 T 06-07-2017 BWK49_RS21410 605b5941c2b2eb7b649237c613d92128 725 Gene3D G3DSA:1.10.540.10 385 460 4.2E-7 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS21410 605b5941c2b2eb7b649237c613d92128 725 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 204 337 9.3E-20 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS21410 605b5941c2b2eb7b649237c613d92128 725 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 571 716 2.8E-19 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS21410 605b5941c2b2eb7b649237c613d92128 725 SUPERFAMILY SSF56645 363 584 2.23E-55 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS21410 605b5941c2b2eb7b649237c613d92128 725 SUPERFAMILY SSF56645 1 200 1.44E-27 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS21555 9d11ba5b5e286938d6ac823ea3cec1bc 150 Gene3D G3DSA:1.10.10.10 2 138 2.9E-31 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS21555 9d11ba5b5e286938d6ac823ea3cec1bc 150 Pfam PF12802 MarR family 29 87 5.5E-12 T 06-07-2017 BWK49_RS21555 9d11ba5b5e286938d6ac823ea3cec1bc 150 SUPERFAMILY SSF46785 2 137 1.15E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS21555 9d11ba5b5e286938d6ac823ea3cec1bc 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 114 134 5.8E-7 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 BWK49_RS21555 9d11ba5b5e286938d6ac823ea3cec1bc 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 84 100 5.8E-7 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 BWK49_RS21555 9d11ba5b5e286938d6ac823ea3cec1bc 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 65 80 5.8E-7 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 BWK49_RS21555 9d11ba5b5e286938d6ac823ea3cec1bc 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 48 64 5.8E-7 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 BWK49_RS21555 9d11ba5b5e286938d6ac823ea3cec1bc 150 SMART SM00347 24 124 1.2E-15 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 BWK49_RS14190 f8c3797b6f2078a323af94f2689e720a 147 Gene3D G3DSA:3.10.450.50 7 137 1.8E-31 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS14190 f8c3797b6f2078a323af94f2689e720a 147 SUPERFAMILY SSF54427 9 136 2.07E-27 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS14190 f8c3797b6f2078a323af94f2689e720a 147 Pfam PF12680 SnoaL-like domain 22 121 6.3E-15 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain BWK49_RS25030 2c299ff7913521478714bc21c3e07de1 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 52 75 6.0E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS25030 2c299ff7913521478714bc21c3e07de1 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 45 6.0E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS25030 2c299ff7913521478714bc21c3e07de1 198 SUPERFAMILY SSF46689 23 99 4.14E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS25030 2c299ff7913521478714bc21c3e07de1 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 32 77 3.0E-13 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS25030 2c299ff7913521478714bc21c3e07de1 198 Gene3D G3DSA:1.10.357.10 21 197 3.7E-40 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS25030 2c299ff7913521478714bc21c3e07de1 198 SUPERFAMILY SSF48498 97 196 1.91E-10 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS27900 0a9a85cb875c6e6d5a1c2f59c496ba91 461 Gene3D G3DSA:3.40.50.1820 9 283 6.2E-40 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS27900 0a9a85cb875c6e6d5a1c2f59c496ba91 461 SUPERFAMILY SSF55073 290 456 1.73E-36 T 06-07-2017 IPR029787 Nucleotide cyclase BWK49_RS27900 0a9a85cb875c6e6d5a1c2f59c496ba91 461 SUPERFAMILY SSF53474 8 282 6.09E-38 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS27900 0a9a85cb875c6e6d5a1c2f59c496ba91 461 SMART SM00044 273 436 3.7E-5 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 BWK49_RS27900 0a9a85cb875c6e6d5a1c2f59c496ba91 461 Pfam PF00561 alpha/beta hydrolase fold 62 142 2.7E-6 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS27900 0a9a85cb875c6e6d5a1c2f59c496ba91 461 Gene3D G3DSA:3.30.70.1230 296 455 3.3E-26 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 BWK49_RS27900 0a9a85cb875c6e6d5a1c2f59c496ba91 461 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 297 449 9.5E-13 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 BWK49_RS14240 23679df29e5d736b81ca35460113e1de 500 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 153 168 6.8E-44 T 06-07-2017 BWK49_RS14240 23679df29e5d736b81ca35460113e1de 500 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 292 308 6.8E-44 T 06-07-2017 BWK49_RS14240 23679df29e5d736b81ca35460113e1de 500 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 310 328 6.8E-44 T 06-07-2017 BWK49_RS14240 23679df29e5d736b81ca35460113e1de 500 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 328 344 6.8E-44 T 06-07-2017 BWK49_RS14240 23679df29e5d736b81ca35460113e1de 500 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 277 292 6.8E-44 T 06-07-2017 BWK49_RS14240 23679df29e5d736b81ca35460113e1de 500 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 14 36 6.8E-44 T 06-07-2017 BWK49_RS14240 23679df29e5d736b81ca35460113e1de 500 Gene3D G3DSA:3.50.50.60 275 315 7.0E-50 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS14240 23679df29e5d736b81ca35460113e1de 500 Gene3D G3DSA:3.50.50.60 14 164 7.0E-50 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS14240 23679df29e5d736b81ca35460113e1de 500 Gene3D G3DSA:3.30.9.10 165 270 4.8E-9 T 06-07-2017 BWK49_RS14240 23679df29e5d736b81ca35460113e1de 500 Gene3D G3DSA:3.30.9.10 325 355 4.8E-9 T 06-07-2017 BWK49_RS14240 23679df29e5d736b81ca35460113e1de 500 ProSitePatterns PS01304 ubiH/COQ6 monooxygenase family signature. 291 304 - T 06-07-2017 IPR018168 Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6, conserved site GO:0016709|GO:0055114 Reactome: R-HSA-2142789 BWK49_RS14240 23679df29e5d736b81ca35460113e1de 500 SUPERFAMILY SSF51905 264 358 1.04E-58 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS14240 23679df29e5d736b81ca35460113e1de 500 SUPERFAMILY SSF51905 15 174 1.04E-58 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS14240 23679df29e5d736b81ca35460113e1de 500 Pfam PF01494 FAD binding domain 14 343 2.2E-78 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 BWK49_RS15080 feba6b531bec2256f0fcdb68a4bced7d 164 Pfam PF02577 Bifunctional nuclease 6 127 5.0E-47 T 06-07-2017 IPR003729 Bifunctional nuclease domain GO:0004518 BWK49_RS15080 feba6b531bec2256f0fcdb68a4bced7d 164 SUPERFAMILY SSF103256 2 135 5.36E-47 T 06-07-2017 IPR003729 Bifunctional nuclease domain GO:0004518 BWK49_RS14505 6990b4ed3bcc1067bc210842a2a956d4 247 Gene3D G3DSA:3.40.50.880 3 208 4.2E-64 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like BWK49_RS14505 6990b4ed3bcc1067bc210842a2a956d4 247 SUPERFAMILY SSF52317 1 185 8.66E-49 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like BWK49_RS14505 6990b4ed3bcc1067bc210842a2a956d4 247 Pfam PF01965 DJ-1/PfpI family 3 162 3.6E-27 T 06-07-2017 IPR002818 DJ-1/PfpI BWK49_RS27885 2bec10bb02bb02b0d5927b2428620d97 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 5.9E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27885 2bec10bb02bb02b0d5927b2428620d97 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 5.9E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27885 2bec10bb02bb02b0d5927b2428620d97 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 5.9E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27885 2bec10bb02bb02b0d5927b2428620d97 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 1.3E-18 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27885 2bec10bb02bb02b0d5927b2428620d97 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 1.3E-18 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27885 2bec10bb02bb02b0d5927b2428620d97 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 1.3E-18 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27885 2bec10bb02bb02b0d5927b2428620d97 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.3E-18 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27885 2bec10bb02bb02b0d5927b2428620d97 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 1.3E-18 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27885 2bec10bb02bb02b0d5927b2428620d97 254 Pfam PF00106 short chain dehydrogenase 6 190 9.4E-45 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27885 2bec10bb02bb02b0d5927b2428620d97 254 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS27885 2bec10bb02bb02b0d5927b2428620d97 254 SUPERFAMILY SSF51735 1 194 2.21E-51 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS27885 2bec10bb02bb02b0d5927b2428620d97 254 Gene3D G3DSA:3.40.50.720 2 198 2.3E-50 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS10300 72669d5fa2601859e442fc43827c73ea 279 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 166 185 1.8E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS10300 72669d5fa2601859e442fc43827c73ea 279 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 89 100 1.8E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS10300 72669d5fa2601859e442fc43827c73ea 279 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 154 1.8E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS10300 72669d5fa2601859e442fc43827c73ea 279 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 153 181 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS10300 72669d5fa2601859e442fc43827c73ea 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 6.7E-20 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS10300 72669d5fa2601859e442fc43827c73ea 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 185 6.7E-20 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS10300 72669d5fa2601859e442fc43827c73ea 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 89 100 6.7E-20 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS10300 72669d5fa2601859e442fc43827c73ea 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 187 204 6.7E-20 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS10300 72669d5fa2601859e442fc43827c73ea 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 156 6.7E-20 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS10300 72669d5fa2601859e442fc43827c73ea 279 SUPERFAMILY SSF51735 12 268 6.72E-57 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS10300 72669d5fa2601859e442fc43827c73ea 279 Gene3D G3DSA:3.40.50.720 11 236 7.1E-57 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS10300 72669d5fa2601859e442fc43827c73ea 279 Pfam PF00106 short chain dehydrogenase 15 206 9.0E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS25830 dd11983218b92da00bd47e5c856631fb 327 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 241 4.0E-64 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 BWK49_RS25830 dd11983218b92da00bd47e5c856631fb 327 Gene3D G3DSA:3.90.25.10 179 312 1.2E-25 T 06-07-2017 BWK49_RS25830 dd11983218b92da00bd47e5c856631fb 327 SUPERFAMILY SSF51735 1 313 6.09E-87 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS25830 dd11983218b92da00bd47e5c856631fb 327 Gene3D G3DSA:3.40.50.720 1 178 5.4E-59 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS17885 16569fdc348ce805719240cc0e0c2499 303 Pfam PF01882 Protein of unknown function DUF58 42 123 6.2E-20 T 06-07-2017 IPR002881 Domain of unknown function DUF58 BWK49_RS06035 043f2c0b39a4b55b4769ec28c729468f 282 SUPERFAMILY SSF51735 6 280 4.06E-67 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS06035 043f2c0b39a4b55b4769ec28c729468f 282 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 99 110 2.6E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS06035 043f2c0b39a4b55b4769ec28c729468f 282 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 195 212 2.6E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS06035 043f2c0b39a4b55b4769ec28c729468f 282 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 193 2.6E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS06035 043f2c0b39a4b55b4769ec28c729468f 282 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 2.6E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS06035 043f2c0b39a4b55b4769ec28c729468f 282 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 243 263 2.6E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS06035 043f2c0b39a4b55b4769ec28c729468f 282 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 164 2.6E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS06035 043f2c0b39a4b55b4769ec28c729468f 282 Gene3D G3DSA:3.40.50.720 1 281 2.1E-72 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS06035 043f2c0b39a4b55b4769ec28c729468f 282 TIGRFAM TIGR03971 SDR_subfam_1: SDR family mycofactocin-dependent oxidoreductase 5 281 4.4E-117 T 06-07-2017 IPR023985 Mycofactocin-dependent oxidoreductase BWK49_RS06035 043f2c0b39a4b55b4769ec28c729468f 282 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 99 110 5.8E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS06035 043f2c0b39a4b55b4769ec28c729468f 282 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 162 5.8E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS06035 043f2c0b39a4b55b4769ec28c729468f 282 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 174 193 5.8E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS06035 043f2c0b39a4b55b4769ec28c729468f 282 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 161 189 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS06035 043f2c0b39a4b55b4769ec28c729468f 282 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 278 1.1E-48 T 06-07-2017 BWK49_RS07185 4db9fd9222d0703d33a530931555aa42 266 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 265 2.4E-57 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 BWK49_RS07185 4db9fd9222d0703d33a530931555aa42 266 Gene3D G3DSA:3.90.226.10 3 264 1.3E-78 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS07185 4db9fd9222d0703d33a530931555aa42 266 SUPERFAMILY SSF52096 5 266 5.89E-79 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS14455 f0b285ededd47cda4ba0eb03b7b35b75 150 Pfam PF12833 Helix-turn-helix domain 38 117 1.2E-22 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 BWK49_RS14455 f0b285ededd47cda4ba0eb03b7b35b75 150 Gene3D G3DSA:1.10.10.60 18 70 5.3E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS14455 f0b285ededd47cda4ba0eb03b7b35b75 150 SUPERFAMILY SSF46689 18 66 1.11E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS14455 f0b285ededd47cda4ba0eb03b7b35b75 150 SMART SM00342 32 115 8.3E-32 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 BWK49_RS14455 f0b285ededd47cda4ba0eb03b7b35b75 150 Gene3D G3DSA:1.10.10.60 71 119 6.7E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS14455 f0b285ededd47cda4ba0eb03b7b35b75 150 SUPERFAMILY SSF46689 68 118 4.3E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS05915 7b09b54479414e68761a1a12d7088449 575 Pfam PF00890 FAD binding domain 9 546 1.0E-86 T 06-07-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 BWK49_RS05915 7b09b54479414e68761a1a12d7088449 575 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 522 537 1.6E-6 T 06-07-2017 BWK49_RS05915 7b09b54479414e68761a1a12d7088449 575 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 9 31 1.6E-6 T 06-07-2017 BWK49_RS05915 7b09b54479414e68761a1a12d7088449 575 Gene3D G3DSA:3.50.50.60 5 142 3.9E-65 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS05915 7b09b54479414e68761a1a12d7088449 575 Gene3D G3DSA:3.50.50.60 502 565 3.9E-65 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS05915 7b09b54479414e68761a1a12d7088449 575 Gene3D G3DSA:3.50.50.60 206 313 3.9E-65 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS05915 7b09b54479414e68761a1a12d7088449 575 Gene3D G3DSA:3.90.700.10 330 496 5.4E-31 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 BWK49_RS05915 7b09b54479414e68761a1a12d7088449 575 SUPERFAMILY SSF51905 199 319 3.62E-41 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS05915 7b09b54479414e68761a1a12d7088449 575 SUPERFAMILY SSF51905 505 569 3.62E-41 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS05915 7b09b54479414e68761a1a12d7088449 575 SUPERFAMILY SSF51905 5 120 3.62E-41 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS05915 7b09b54479414e68761a1a12d7088449 575 SUPERFAMILY SSF56425 314 499 3.4E-33 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 BWK49_RS16790 3118194eac64539e2c4b2353b6cb7c15 222 SUPERFAMILY SSF48498 109 210 1.01E-20 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS16790 3118194eac64539e2c4b2353b6cb7c15 222 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 63 86 3.7E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS16790 3118194eac64539e2c4b2353b6cb7c15 222 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 55 3.7E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS16790 3118194eac64539e2c4b2353b6cb7c15 222 Gene3D G3DSA:1.10.357.10 37 210 3.6E-34 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS16790 3118194eac64539e2c4b2353b6cb7c15 222 Pfam PF16925 Bacterial transcriptional repressor C-terminal 109 212 4.3E-22 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS16790 3118194eac64539e2c4b2353b6cb7c15 222 Pfam PF00440 Bacterial regulatory proteins, tetR family 42 88 1.7E-13 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS16790 3118194eac64539e2c4b2353b6cb7c15 222 SUPERFAMILY SSF46689 32 112 2.34E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS03010 3e0cdbf2fc3e8a901b6e84d05fa0a9f1 247 Pfam PF04402 Protein of unknown function (DUF541) 45 244 1.1E-40 T 06-07-2017 IPR007497 Protein of unknown function DUF541 BWK49_RS19710 80064df3d107105412b523bb72dbf542 260 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 244 1.1E-62 T 06-07-2017 BWK49_RS19710 80064df3d107105412b523bb72dbf542 260 SUPERFAMILY SSF51735 8 246 1.16E-79 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS19710 80064df3d107105412b523bb72dbf542 260 Gene3D G3DSA:3.40.50.720 4 246 1.0E-81 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS19710 80064df3d107105412b523bb72dbf542 260 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS19710 80064df3d107105412b523bb72dbf542 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 7.0E-43 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS19710 80064df3d107105412b523bb72dbf542 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 7.0E-43 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS19710 80064df3d107105412b523bb72dbf542 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 7.0E-43 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS19710 80064df3d107105412b523bb72dbf542 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 7.0E-43 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS19710 80064df3d107105412b523bb72dbf542 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 7.0E-43 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS19710 80064df3d107105412b523bb72dbf542 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 7.0E-43 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS19710 80064df3d107105412b523bb72dbf542 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 2.3E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS19710 80064df3d107105412b523bb72dbf542 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 2.3E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS19710 80064df3d107105412b523bb72dbf542 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 2.3E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS03085 4a91bbdae2c097d162c79fce604fd15a 303 SUPERFAMILY SSF48179 179 292 3.4E-18 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 BWK49_RS03085 4a91bbdae2c097d162c79fce604fd15a 303 Gene3D G3DSA:1.10.1040.20 179 291 1.5E-24 T 06-07-2017 IPR018931 Domain of unknown function DUF2520 BWK49_RS03085 4a91bbdae2c097d162c79fce604fd15a 303 Pfam PF10727 Rossmann-like domain 8 128 3.1E-60 T 06-07-2017 IPR019665 Putative oxidoreductase/dehydrogenase, Rossmann-like domain BWK49_RS03085 4a91bbdae2c097d162c79fce604fd15a 303 Pfam PF10728 Domain of unknown function (DUF2520) 145 286 2.1E-38 T 06-07-2017 IPR018931 Domain of unknown function DUF2520 BWK49_RS03085 4a91bbdae2c097d162c79fce604fd15a 303 Gene3D G3DSA:3.40.50.720 12 175 8.5E-33 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS03085 4a91bbdae2c097d162c79fce604fd15a 303 SUPERFAMILY SSF51735 13 176 7.24E-23 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS09450 f214209f321097bdd562648e211c8b50 634 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 369 393 3.4E-5 T 06-07-2017 IPR023908 xxxLxxG heptad repeat BWK49_RS09450 f214209f321097bdd562648e211c8b50 634 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 347 373 2.4E-4 T 06-07-2017 IPR023908 xxxLxxG heptad repeat BWK49_RS09450 f214209f321097bdd562648e211c8b50 634 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 196 223 3.5E-6 T 06-07-2017 IPR023908 xxxLxxG heptad repeat BWK49_RS09450 f214209f321097bdd562648e211c8b50 634 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 180 202 5.0E-5 T 06-07-2017 IPR023908 xxxLxxG heptad repeat BWK49_RS09450 f214209f321097bdd562648e211c8b50 634 TIGRFAM TIGR03061 pip_yhgE_Nterm: YhgE/Pip N-terminal domain 9 172 2.9E-58 T 06-07-2017 IPR017500 Phage infection protein, YhgE, N-terminal BWK49_RS09450 f214209f321097bdd562648e211c8b50 634 TIGRFAM TIGR03062 pip_yhgE_Cterm: YhgE/Pip C-terminal domain 415 621 4.1E-72 T 06-07-2017 IPR017501 Phage infection protein, YhgE, C-terminal BWK49_RS09450 f214209f321097bdd562648e211c8b50 634 Pfam PF12698 ABC-2 family transporter protein 24 165 2.4E-10 T 06-07-2017 BWK49_RS09450 f214209f321097bdd562648e211c8b50 634 Pfam PF12698 ABC-2 family transporter protein 408 613 1.9E-16 T 06-07-2017 BWK49_RS09450 f214209f321097bdd562648e211c8b50 634 SUPERFAMILY SSF58104 192 404 1.88E-6 T 06-07-2017 BWK49_RS08250 6562e0ee0f64315b65753d5b1bd849d2 1232 Gene3D G3DSA:3.40.50.740 153 223 3.0E-8 T 06-07-2017 BWK49_RS08250 6562e0ee0f64315b65753d5b1bd849d2 1232 Gene3D G3DSA:2.20.25.90 62 108 1.0E-30 T 06-07-2017 BWK49_RS08250 6562e0ee0f64315b65753d5b1bd849d2 1232 Gene3D G3DSA:3.40.50.740 591 775 1.9E-47 T 06-07-2017 BWK49_RS08250 6562e0ee0f64315b65753d5b1bd849d2 1232 Gene3D G3DSA:3.40.228.10 490 590 9.4E-82 T 06-07-2017 BWK49_RS08250 6562e0ee0f64315b65753d5b1bd849d2 1232 Gene3D G3DSA:3.40.228.10 231 346 9.4E-82 T 06-07-2017 BWK49_RS08250 6562e0ee0f64315b65753d5b1bd849d2 1232 SUPERFAMILY SSF53706 15 1064 0.0 T 06-07-2017 BWK49_RS08250 6562e0ee0f64315b65753d5b1bd849d2 1232 Pfam PF00384 Molybdopterin oxidoreductase 118 828 5.3E-131 T 06-07-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS08250 6562e0ee0f64315b65753d5b1bd849d2 1232 Pfam PF01568 Molydopterin dinucleotide binding domain 1086 1195 6.8E-19 T 06-07-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 BWK49_RS08250 6562e0ee0f64315b65753d5b1bd849d2 1232 Gene3D G3DSA:2.40.40.20 1054 1225 1.5E-35 T 06-07-2017 BWK49_RS08250 6562e0ee0f64315b65753d5b1bd849d2 1232 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 58 76 - T 06-07-2017 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 KEGG: 00910+1.7.99.4 BWK49_RS08250 6562e0ee0f64315b65753d5b1bd849d2 1232 Gene3D G3DSA:3.90.55.10 776 836 5.2E-6 T 06-07-2017 BWK49_RS08250 6562e0ee0f64315b65753d5b1bd849d2 1232 TIGRFAM TIGR01580 narG: nitrate reductase, alpha subunit 19 1226 0.0 T 06-07-2017 IPR006468 Nitrate reductase, alpha subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.99.4 BWK49_RS08250 6562e0ee0f64315b65753d5b1bd849d2 1232 SMART SM00926 53 115 5.6E-5 T 06-07-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS08250 6562e0ee0f64315b65753d5b1bd849d2 1232 SUPERFAMILY SSF50692 1086 1226 2.26E-39 T 06-07-2017 IPR009010 Aspartate decarboxylase-like domain BWK49_RS08250 6562e0ee0f64315b65753d5b1bd849d2 1232 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 773 790 - T 06-07-2017 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 BWK49_RS18345 1992a778bbc18df76cc834ee75294ba8 160 SUPERFAMILY SSF52121 12 157 8.24E-52 T 06-07-2017 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 BWK49_RS18345 1992a778bbc18df76cc834ee75294ba8 160 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 18 150 1.5E-40 T 06-07-2017 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 BWK49_RS18345 1992a778bbc18df76cc834ee75294ba8 160 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 17 151 5.3E-48 T 06-07-2017 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 BWK49_RS18345 1992a778bbc18df76cc834ee75294ba8 160 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 13 156 27.204 T 06-07-2017 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 BWK49_RS18345 1992a778bbc18df76cc834ee75294ba8 160 Gene3D G3DSA:3.40.50.960 13 157 5.5E-56 T 06-07-2017 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 BWK49_RS11555 b677994306d999cfba4d4c593e9bde24 373 Gene3D G3DSA:3.20.20.30 3 362 9.3E-99 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS11555 b677994306d999cfba4d4c593e9bde24 373 Pfam PF00296 Luciferase-like monooxygenase 29 280 3.2E-36 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS11555 b677994306d999cfba4d4c593e9bde24 373 SUPERFAMILY SSF51679 4 362 1.77E-75 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS08120 0c82a155a84bd681165b9edd22f3eef9 338 Pfam PF00890 FAD binding domain 7 38 1.8E-4 T 06-07-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 BWK49_RS08120 0c82a155a84bd681165b9edd22f3eef9 338 Pfam PF01494 FAD binding domain 104 170 2.1E-8 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 BWK49_RS08120 0c82a155a84bd681165b9edd22f3eef9 338 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 134 149 1.3E-15 T 06-07-2017 BWK49_RS08120 0c82a155a84bd681165b9edd22f3eef9 338 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 244 259 1.3E-15 T 06-07-2017 BWK49_RS08120 0c82a155a84bd681165b9edd22f3eef9 338 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 1.3E-15 T 06-07-2017 BWK49_RS08120 0c82a155a84bd681165b9edd22f3eef9 338 Gene3D G3DSA:3.50.50.60 2 158 6.3E-30 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS08120 0c82a155a84bd681165b9edd22f3eef9 338 Gene3D G3DSA:3.50.50.60 242 281 6.3E-30 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS08120 0c82a155a84bd681165b9edd22f3eef9 338 SUPERFAMILY SSF51905 239 310 8.84E-37 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS08120 0c82a155a84bd681165b9edd22f3eef9 338 SUPERFAMILY SSF51905 6 155 8.84E-37 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS15205 f82e79b6c8e023214ffbb8c2191248ed 389 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 307 385 3.4E-20 T 06-07-2017 IPR022171 PPE family, C-terminal BWK49_RS15205 f82e79b6c8e023214ffbb8c2191248ed 389 SUPERFAMILY SSF140459 4 175 7.85E-66 T 06-07-2017 BWK49_RS15205 f82e79b6c8e023214ffbb8c2191248ed 389 Pfam PF00823 PPE family 8 163 2.2E-66 T 06-07-2017 IPR000030 PPE family BWK49_RS00450 9ca9c6a9f763816e8ddae59cb133f4be 398 Gene3D G3DSA:1.10.630.10 11 394 7.7E-97 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS00450 9ca9c6a9f763816e8ddae59cb133f4be 398 Pfam PF00067 Cytochrome P450 199 369 3.0E-19 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS00450 9ca9c6a9f763816e8ddae59cb133f4be 398 SUPERFAMILY SSF48264 15 395 6.42E-79 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS00450 9ca9c6a9f763816e8ddae59cb133f4be 398 PRINTS PR00385 P450 superfamily signature 274 285 3.6E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS00450 9ca9c6a9f763816e8ddae59cb133f4be 398 PRINTS PR00385 P450 superfamily signature 239 256 3.6E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS00450 9ca9c6a9f763816e8ddae59cb133f4be 398 PRINTS PR00385 P450 superfamily signature 339 348 3.6E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS00450 9ca9c6a9f763816e8ddae59cb133f4be 398 PRINTS PR00385 P450 superfamily signature 348 359 3.6E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS00450 9ca9c6a9f763816e8ddae59cb133f4be 398 PRINTS PR00359 B-class P450 signature 188 210 1.5E-38 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS00450 9ca9c6a9f763816e8ddae59cb133f4be 398 PRINTS PR00359 B-class P450 signature 339 348 1.5E-38 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS00450 9ca9c6a9f763816e8ddae59cb133f4be 398 PRINTS PR00359 B-class P450 signature 133 149 1.5E-38 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS00450 9ca9c6a9f763816e8ddae59cb133f4be 398 PRINTS PR00359 B-class P450 signature 274 285 1.5E-38 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS00450 9ca9c6a9f763816e8ddae59cb133f4be 398 PRINTS PR00359 B-class P450 signature 319 334 1.5E-38 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS00450 9ca9c6a9f763816e8ddae59cb133f4be 398 PRINTS PR00359 B-class P450 signature 87 98 1.5E-38 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS00450 9ca9c6a9f763816e8ddae59cb133f4be 398 PRINTS PR00359 B-class P450 signature 291 318 1.5E-38 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS00450 9ca9c6a9f763816e8ddae59cb133f4be 398 PRINTS PR00359 B-class P450 signature 348 359 1.5E-38 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS00450 9ca9c6a9f763816e8ddae59cb133f4be 398 PRINTS PR00359 B-class P450 signature 150 165 1.5E-38 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS00450 9ca9c6a9f763816e8ddae59cb133f4be 398 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 341 350 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 BWK49_RS09125 2924cd19182e441502e5f03962cea748 271 Pfam PF01177 Asp/Glu/Hydantoin racemase 8 216 8.9E-33 T 06-07-2017 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 BWK49_RS09125 2924cd19182e441502e5f03962cea748 271 SUPERFAMILY SSF53681 111 260 6.05E-39 T 06-07-2017 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 BWK49_RS09125 2924cd19182e441502e5f03962cea748 271 SUPERFAMILY SSF53681 7 109 1.31E-32 T 06-07-2017 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 BWK49_RS09125 2924cd19182e441502e5f03962cea748 271 Gene3D G3DSA:3.40.50.1860 6 174 1.8E-51 T 06-07-2017 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 BWK49_RS09125 2924cd19182e441502e5f03962cea748 271 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 72 80 - T 06-07-2017 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 BWK49_RS09125 2924cd19182e441502e5f03962cea748 271 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 181 191 - T 06-07-2017 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 BWK49_RS09125 2924cd19182e441502e5f03962cea748 271 TIGRFAM TIGR00067 glut_race: glutamate racemase 8 254 3.1E-67 T 06-07-2017 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 BWK49_RS09125 2924cd19182e441502e5f03962cea748 271 Hamap MF_00258 Glutamate racemase [murI]. 6 258 37.086 T 06-07-2017 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 BWK49_RS14325 da6ab02770bc79aff902047a1b8a3add 495 Gene3D G3DSA:2.102.10.10 397 494 4.2E-20 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS14325 da6ab02770bc79aff902047a1b8a3add 495 Pfam PF00355 Rieske [2Fe-2S] domain 443 493 1.1E-6 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS14325 da6ab02770bc79aff902047a1b8a3add 495 SUPERFAMILY SSF51905 329 387 2.33E-38 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS14325 da6ab02770bc79aff902047a1b8a3add 495 SUPERFAMILY SSF51905 21 244 2.33E-38 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS14325 da6ab02770bc79aff902047a1b8a3add 495 Pfam PF01266 FAD dependent oxidoreductase 22 367 9.5E-44 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 BWK49_RS14325 da6ab02770bc79aff902047a1b8a3add 495 Gene3D G3DSA:3.50.50.60 329 377 5.4E-39 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS14325 da6ab02770bc79aff902047a1b8a3add 495 Gene3D G3DSA:3.50.50.60 16 111 5.4E-39 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS14325 da6ab02770bc79aff902047a1b8a3add 495 Gene3D G3DSA:3.50.50.60 157 242 5.4E-39 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS14325 da6ab02770bc79aff902047a1b8a3add 495 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 22 44 1.7E-6 T 06-07-2017 BWK49_RS14325 da6ab02770bc79aff902047a1b8a3add 495 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 278 293 1.7E-6 T 06-07-2017 BWK49_RS14325 da6ab02770bc79aff902047a1b8a3add 495 SUPERFAMILY SSF50022 386 494 4.98E-18 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS20580 4101c4fecdda036a7c029ea1324777ac 464 Pfam PF08388 Group II intron, maturase-specific domain 343 416 3.3E-17 T 06-07-2017 IPR013597 Group II intron, maturase-specific BWK49_RS20580 4101c4fecdda036a7c029ea1324777ac 464 SUPERFAMILY SSF56672 34 405 7.63E-46 T 06-07-2017 BWK49_RS20580 4101c4fecdda036a7c029ea1324777ac 464 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 88 321 2.5E-38 T 06-07-2017 IPR000477 Reverse transcriptase domain BWK49_RS20580 4101c4fecdda036a7c029ea1324777ac 464 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 29 407 1.2E-109 T 06-07-2017 IPR030931 Group II intron reverse transcriptase/maturase BWK49_RS09240 e4ce94403692894f9e9faeed83808707 489 Gene3D G3DSA:3.40.50.980 6 151 2.3E-14 T 06-07-2017 BWK49_RS09240 e4ce94403692894f9e9faeed83808707 489 Pfam PF00501 AMP-binding enzyme 16 384 2.6E-44 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS09240 e4ce94403692894f9e9faeed83808707 489 Pfam PF13193 AMP-binding enzyme C-terminal domain 394 468 5.4E-18 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS09240 e4ce94403692894f9e9faeed83808707 489 Gene3D G3DSA:3.40.50.980 152 306 1.6E-21 T 06-07-2017 BWK49_RS09240 e4ce94403692894f9e9faeed83808707 489 Gene3D G3DSA:3.30.300.30 379 476 2.6E-26 T 06-07-2017 BWK49_RS09240 e4ce94403692894f9e9faeed83808707 489 SUPERFAMILY SSF56801 5 481 1.57E-94 T 06-07-2017 BWK49_RS09240 e4ce94403692894f9e9faeed83808707 489 Gene3D G3DSA:2.30.38.10 317 378 2.5E-6 T 06-07-2017 BWK49_RS26465 b837b0a19f8baa0a6e28f0d55c5a8b87 301 SUPERFAMILY SSF53335 14 283 1.33E-71 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS26465 b837b0a19f8baa0a6e28f0d55c5a8b87 301 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 16 278 3.5E-86 T 06-07-2017 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 BWK49_RS26465 b837b0a19f8baa0a6e28f0d55c5a8b87 301 Gene3D G3DSA:3.40.50.150 80 220 3.9E-15 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS26465 b837b0a19f8baa0a6e28f0d55c5a8b87 301 Pfam PF04072 Leucine carboxyl methyltransferase 18 198 2.7E-59 T 06-07-2017 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 BWK49_RS00570 39589a0af9eeb626fac8625d3f5368a4 318 SUPERFAMILY SSF51556 23 316 6.46E-68 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS00570 39589a0af9eeb626fac8625d3f5368a4 318 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 24 314 5.9E-74 T 06-07-2017 IPR008257 Renal dipeptidase family GO:0006508|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 BWK49_RS00570 39589a0af9eeb626fac8625d3f5368a4 318 Gene3D G3DSA:3.20.20.140 43 317 1.2E-77 T 06-07-2017 BWK49_RS00160 b50100247b110f4d0d5a1117d5f30293 519 Gene3D G3DSA:3.40.50.980 6 162 1.9E-7 T 06-07-2017 BWK49_RS00160 b50100247b110f4d0d5a1117d5f30293 519 Gene3D G3DSA:3.40.50.980 163 323 2.7E-23 T 06-07-2017 BWK49_RS00160 b50100247b110f4d0d5a1117d5f30293 519 ProSitePatterns PS00455 Putative AMP-binding domain signature. 157 168 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS00160 b50100247b110f4d0d5a1117d5f30293 519 SUPERFAMILY SSF56801 3 518 1.11E-73 T 06-07-2017 BWK49_RS00160 b50100247b110f4d0d5a1117d5f30293 519 Gene3D G3DSA:3.30.300.30 414 516 8.0E-17 T 06-07-2017 BWK49_RS00160 b50100247b110f4d0d5a1117d5f30293 519 Pfam PF00501 AMP-binding enzyme 13 420 2.2E-47 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS00160 b50100247b110f4d0d5a1117d5f30293 519 Gene3D G3DSA:2.30.38.10 345 413 1.2E-13 T 06-07-2017 BWK49_RS21780 2bb09284c81658be128df40f236b52bd 146 Gene3D G3DSA:2.30.110.10 39 102 1.9E-4 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 BWK49_RS21780 2bb09284c81658be128df40f236b52bd 146 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 29 142 7.2E-37 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 BWK49_RS21780 2bb09284c81658be128df40f236b52bd 146 Pfam PF04075 Domain of unknown function (DUF385) 13 143 1.5E-50 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 BWK49_RS14685 d6496b65550b1755bdd1d7e1f71f3ded 645 Gene3D G3DSA:3.50.50.60 142 350 4.9E-58 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS14685 d6496b65550b1755bdd1d7e1f71f3ded 645 Gene3D G3DSA:3.50.50.60 461 638 9.1E-16 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS14685 d6496b65550b1755bdd1d7e1f71f3ded 645 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 142 161 4.6E-5 T 06-07-2017 BWK49_RS14685 d6496b65550b1755bdd1d7e1f71f3ded 645 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 310 328 4.6E-5 T 06-07-2017 BWK49_RS14685 d6496b65550b1755bdd1d7e1f71f3ded 645 SUPERFAMILY SSF51905 142 366 5.55E-54 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS14685 d6496b65550b1755bdd1d7e1f71f3ded 645 SUPERFAMILY SSF51905 446 545 5.55E-54 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS14685 d6496b65550b1755bdd1d7e1f71f3ded 645 Pfam PF00743 Flavin-binding monooxygenase-like 189 345 4.3E-15 T 06-07-2017 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 BWK49_RS05270 70aa74da23d04fbb5c3a1771560cb49b 207 Pfam PF00665 Integrase core domain 64 171 1.5E-10 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 BWK49_RS05270 70aa74da23d04fbb5c3a1771560cb49b 207 Gene3D G3DSA:3.30.420.10 70 184 4.4E-11 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS05270 70aa74da23d04fbb5c3a1771560cb49b 207 SUPERFAMILY SSF53098 61 204 2.12E-15 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS15695 691072cdf67174129732882be7618975 281 Gene3D G3DSA:3.40.50.720 10 257 5.6E-81 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS15695 691072cdf67174129732882be7618975 281 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 23 256 8.7E-64 T 06-07-2017 BWK49_RS15695 691072cdf67174129732882be7618975 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 89 100 1.3E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15695 691072cdf67174129732882be7618975 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 164 183 1.3E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15695 691072cdf67174129732882be7618975 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 144 152 1.3E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15695 691072cdf67174129732882be7618975 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 138 154 1.6E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15695 691072cdf67174129732882be7618975 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 185 202 1.6E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15695 691072cdf67174129732882be7618975 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 89 100 1.6E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15695 691072cdf67174129732882be7618975 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 221 241 1.6E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15695 691072cdf67174129732882be7618975 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 183 1.6E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15695 691072cdf67174129732882be7618975 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 15 32 1.6E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15695 691072cdf67174129732882be7618975 281 SUPERFAMILY SSF51735 13 257 7.46E-79 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS18485 14e637f8893241fd22316871bd5c40d4 430 SUPERFAMILY SSF51338 2 51 5.22E-25 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 BWK49_RS18485 14e637f8893241fd22316871bd5c40d4 430 SUPERFAMILY SSF51338 368 427 5.22E-25 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 BWK49_RS18485 14e637f8893241fd22316871bd5c40d4 430 Hamap MF_00220_B Dihydroorotase [pyrC]. 2 426 43.726 T 06-07-2017 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686 BWK49_RS18485 14e637f8893241fd22316871bd5c40d4 430 ProSitePatterns PS00483 Dihydroorotase signature 2. 302 313 - T 06-07-2017 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686 BWK49_RS18485 14e637f8893241fd22316871bd5c40d4 430 SUPERFAMILY SSF51556 52 367 3.76E-98 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS18485 14e637f8893241fd22316871bd5c40d4 430 Gene3D G3DSA:2.30.40.10 4 66 2.2E-20 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 BWK49_RS18485 14e637f8893241fd22316871bd5c40d4 430 Gene3D G3DSA:3.20.20.140 67 408 3.0E-103 T 06-07-2017 BWK49_RS18485 14e637f8893241fd22316871bd5c40d4 430 Pfam PF01979 Amidohydrolase family 48 421 5.6E-23 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 BWK49_RS18485 14e637f8893241fd22316871bd5c40d4 430 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 14 425 6.0E-156 T 06-07-2017 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686 BWK49_RS05110 f1e09ad0231cfc35fc87be08b30eb3c5 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 2.5E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS05110 f1e09ad0231cfc35fc87be08b30eb3c5 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 2.5E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS05110 f1e09ad0231cfc35fc87be08b30eb3c5 193 Gene3D G3DSA:1.10.10.60 12 56 3.2E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS05110 f1e09ad0231cfc35fc87be08b30eb3c5 193 Gene3D G3DSA:1.10.357.10 57 193 1.7E-18 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS05110 f1e09ad0231cfc35fc87be08b30eb3c5 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 54 1.7E-14 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS05110 f1e09ad0231cfc35fc87be08b30eb3c5 193 SUPERFAMILY SSF46689 12 81 9.22E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS05110 f1e09ad0231cfc35fc87be08b30eb3c5 193 SUPERFAMILY SSF48498 80 192 2.26E-10 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS25665 8ff2b269e10e5356bfd1d3e460becaa5 286 Pfam PF01066 CDP-alcohol phosphatidyltransferase 14 78 3.7E-11 T 06-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 BWK49_RS25665 8ff2b269e10e5356bfd1d3e460becaa5 286 TIGRFAM TIGR00473 pssA: CDP-diacylglycerol-serine O-phosphatidyltransferase 20 185 6.0E-37 T 06-07-2017 IPR004533 CDP-diacylglycerol--serine O-phosphatidyltransferase KEGG: 00260+2.7.8.8|KEGG: 00564+2.7.8.8|MetaCyc: PWY-5669 BWK49_RS25665 8ff2b269e10e5356bfd1d3e460becaa5 286 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 56 78 - T 06-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 BWK49_RS18030 df7fc21915e03a335a71f47f4d12fbad 314 SUPERFAMILY SSF50129 3 149 4.25E-24 T 06-07-2017 IPR011032 GroES-like BWK49_RS18030 df7fc21915e03a335a71f47f4d12fbad 314 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 90 4.3E-8 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 BWK49_RS18030 df7fc21915e03a335a71f47f4d12fbad 314 SMART SM00829 13 307 1.1E-9 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 BWK49_RS18030 df7fc21915e03a335a71f47f4d12fbad 314 Gene3D G3DSA:3.90.180.10 13 91 4.8E-10 T 06-07-2017 IPR011032 GroES-like BWK49_RS18030 df7fc21915e03a335a71f47f4d12fbad 314 SUPERFAMILY SSF51735 117 277 2.22E-21 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS18030 df7fc21915e03a335a71f47f4d12fbad 314 Pfam PF13602 Zinc-binding dehydrogenase 188 307 1.6E-13 T 06-07-2017 BWK49_RS18030 df7fc21915e03a335a71f47f4d12fbad 314 Gene3D G3DSA:3.40.50.720 110 278 5.4E-27 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS15815 6ec173a2c8c625f2a01b31378b5664a6 472 Gene3D G3DSA:3.40.605.10 6 256 4.3E-80 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 BWK49_RS15815 6ec173a2c8c625f2a01b31378b5664a6 472 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 272 283 - T 06-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 BWK49_RS15815 6ec173a2c8c625f2a01b31378b5664a6 472 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 244 251 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 BWK49_RS15815 6ec173a2c8c625f2a01b31378b5664a6 472 Gene3D G3DSA:3.40.309.10 257 443 8.1E-59 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 BWK49_RS15815 6ec173a2c8c625f2a01b31378b5664a6 472 SUPERFAMILY SSF53720 4 468 3.67E-147 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 BWK49_RS15815 6ec173a2c8c625f2a01b31378b5664a6 472 Pfam PF00171 Aldehyde dehydrogenase family 15 467 1.5E-153 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 BWK49_RS07245 e6d9d64d29280f64e0e10a36739e76fd 529 Pfam PF16192 C-terminal four TMM region of protein-O-mannosyltransferase 329 528 1.6E-19 T 06-07-2017 IPR032421 Protein O-mannosyl-transferase, C-terminal four TM domain KEGG: 00500+2.4.1.10|KEGG: 00514+2.4.1.109|MetaCyc: PWY-822|Reactome: R-HSA-5173105 BWK49_RS07245 e6d9d64d29280f64e0e10a36739e76fd 529 Pfam PF02366 Dolichyl-phosphate-mannose-protein mannosyltransferase 121 298 4.7E-14 T 06-07-2017 IPR003342 Glycosyl transferase family 39/83 GO:0000030|GO:0006493|GO:0016020 Reactome: R-HSA-5173105 BWK49_RS27670 55481c46dc2f1cc6030cbc1cb24fa523 153 SMART SM00347 31 131 1.3E-14 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 BWK49_RS27670 55481c46dc2f1cc6030cbc1cb24fa523 153 SUPERFAMILY SSF46785 9 142 3.9E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS27670 55481c46dc2f1cc6030cbc1cb24fa523 153 Gene3D G3DSA:1.10.10.10 11 141 3.9E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS27670 55481c46dc2f1cc6030cbc1cb24fa523 153 Pfam PF12802 MarR family 38 94 6.6E-10 T 06-07-2017 BWK49_RS04680 e75bc3ca28b30cb9b08b750248e9e8a2 380 PIRSF PIRSF016578 3 380 7.4E-12 T 06-07-2017 BWK49_RS04680 e75bc3ca28b30cb9b08b750248e9e8a2 380 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 232 380 7.0E-40 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS04680 e75bc3ca28b30cb9b08b750248e9e8a2 380 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 339 358 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 BWK49_RS04680 e75bc3ca28b30cb9b08b750248e9e8a2 380 Gene3D G3DSA:2.40.110.10 123 219 7.2E-39 T 06-07-2017 BWK49_RS04680 e75bc3ca28b30cb9b08b750248e9e8a2 380 Gene3D G3DSA:1.20.140.10 220 380 2.5E-52 T 06-07-2017 BWK49_RS04680 e75bc3ca28b30cb9b08b750248e9e8a2 380 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 120 5.8E-30 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS04680 e75bc3ca28b30cb9b08b750248e9e8a2 380 SUPERFAMILY SSF47203 231 380 1.45E-47 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS04680 e75bc3ca28b30cb9b08b750248e9e8a2 380 SUPERFAMILY SSF56645 5 244 7.2E-81 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS04680 e75bc3ca28b30cb9b08b750248e9e8a2 380 Gene3D G3DSA:1.10.540.10 5 121 1.8E-33 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS04680 e75bc3ca28b30cb9b08b750248e9e8a2 380 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 124 219 2.9E-26 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 BWK49_RS26115 b267cde5389947098338647f7875ac4b 392 ProSitePatterns PS00636 Nt-dnaJ domain signature. 52 71 - T 06-07-2017 IPR018253 DnaJ domain, conserved site BWK49_RS26115 b267cde5389947098338647f7875ac4b 392 Gene3D G3DSA:2.60.260.20 284 359 9.6E-22 T 06-07-2017 BWK49_RS26115 b267cde5389947098338647f7875ac4b 392 SMART SM00271 9 67 2.3E-26 T 06-07-2017 IPR001623 DnaJ domain BWK49_RS26115 b267cde5389947098338647f7875ac4b 392 Gene3D G3DSA:1.10.287.110 3 76 1.3E-28 T 06-07-2017 IPR001623 DnaJ domain BWK49_RS26115 b267cde5389947098338647f7875ac4b 392 Gene3D G3DSA:1.10.287.110 114 128 1.3E-28 T 06-07-2017 IPR001623 DnaJ domain BWK49_RS26115 b267cde5389947098338647f7875ac4b 392 Pfam PF00684 DnaJ central domain 174 234 6.5E-13 T 06-07-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 BWK49_RS26115 b267cde5389947098338647f7875ac4b 392 PRINTS PR00625 DnaJ domain signature 30 45 3.6E-21 T 06-07-2017 IPR001623 DnaJ domain BWK49_RS26115 b267cde5389947098338647f7875ac4b 392 PRINTS PR00625 DnaJ domain signature 47 67 3.6E-21 T 06-07-2017 IPR001623 DnaJ domain BWK49_RS26115 b267cde5389947098338647f7875ac4b 392 PRINTS PR00625 DnaJ domain signature 12 30 3.6E-21 T 06-07-2017 IPR001623 DnaJ domain BWK49_RS26115 b267cde5389947098338647f7875ac4b 392 PRINTS PR00625 DnaJ domain signature 67 86 3.6E-21 T 06-07-2017 IPR001623 DnaJ domain BWK49_RS26115 b267cde5389947098338647f7875ac4b 392 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 10 376 1.5E-123 T 06-07-2017 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 BWK49_RS26115 b267cde5389947098338647f7875ac4b 392 Gene3D G3DSA:2.60.260.20 237 281 4.3E-22 T 06-07-2017 BWK49_RS26115 b267cde5389947098338647f7875ac4b 392 Gene3D G3DSA:2.60.260.20 135 169 4.3E-22 T 06-07-2017 BWK49_RS26115 b267cde5389947098338647f7875ac4b 392 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 7 386 37.392 T 06-07-2017 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 BWK49_RS26115 b267cde5389947098338647f7875ac4b 392 SUPERFAMILY SSF49493 286 368 9.68E-22 T 06-07-2017 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 BWK49_RS26115 b267cde5389947098338647f7875ac4b 392 SUPERFAMILY SSF57938 161 237 1.44E-18 T 06-07-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 BWK49_RS26115 b267cde5389947098338647f7875ac4b 392 Gene3D G3DSA:2.10.230.10 170 236 9.3E-22 T 06-07-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 BWK49_RS26115 b267cde5389947098338647f7875ac4b 392 SUPERFAMILY SSF46565 8 99 4.32E-28 T 06-07-2017 IPR001623 DnaJ domain BWK49_RS26115 b267cde5389947098338647f7875ac4b 392 Pfam PF00226 DnaJ domain 10 72 7.4E-25 T 06-07-2017 IPR001623 DnaJ domain BWK49_RS26115 b267cde5389947098338647f7875ac4b 392 SUPERFAMILY SSF49493 240 288 1.06E-18 T 06-07-2017 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 BWK49_RS26115 b267cde5389947098338647f7875ac4b 392 SUPERFAMILY SSF49493 140 196 1.06E-18 T 06-07-2017 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 BWK49_RS26115 b267cde5389947098338647f7875ac4b 392 Pfam PF01556 DnaJ C terminal domain 148 359 1.4E-38 T 06-07-2017 IPR002939 Chaperone DnaJ, C-terminal BWK49_RS27910 0b9c3c5f83da022b21696fe59776e08f 150 Gene3D G3DSA:3.30.530.20 3 148 1.2E-11 T 06-07-2017 IPR023393 START-like domain BWK49_RS27910 0b9c3c5f83da022b21696fe59776e08f 150 SUPERFAMILY SSF55961 5 148 2.47E-20 T 06-07-2017 BWK49_RS27910 0b9c3c5f83da022b21696fe59776e08f 150 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 8 146 8.9E-8 T 06-07-2017 IPR019587 Polyketide cyclase/dehydrase BWK49_RS20280 449be7dcbe7e00ad42c619edbc897377 113 SUPERFAMILY SSF50104 1 112 3.31E-45 T 06-07-2017 IPR008991 Translation protein SH3-like domain BWK49_RS20280 449be7dcbe7e00ad42c619edbc897377 113 PRINTS PR00061 Ribosomal protein L19 signature 87 112 1.8E-40 T 06-07-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS20280 449be7dcbe7e00ad42c619edbc897377 113 PRINTS PR00061 Ribosomal protein L19 signature 3 32 1.8E-40 T 06-07-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS20280 449be7dcbe7e00ad42c619edbc897377 113 PRINTS PR00061 Ribosomal protein L19 signature 33 62 1.8E-40 T 06-07-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS20280 449be7dcbe7e00ad42c619edbc897377 113 ProSitePatterns PS01015 Ribosomal protein L19 signature. 85 100 - T 06-07-2017 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS20280 449be7dcbe7e00ad42c619edbc897377 113 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 1 113 30.023 T 06-07-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS20280 449be7dcbe7e00ad42c619edbc897377 113 PIRSF PIRSF002191 1 113 9.7E-50 T 06-07-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS20280 449be7dcbe7e00ad42c619edbc897377 113 Pfam PF01245 Ribosomal protein L19 5 112 6.0E-50 T 06-07-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS20280 449be7dcbe7e00ad42c619edbc897377 113 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 2 112 2.2E-50 T 06-07-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS13580 4fb6bc674a1afcaf1780dfa636921695 173 Pfam PF04186 FxsA cytoplasmic membrane protein 5 107 2.4E-19 T 06-07-2017 IPR007313 FxsA cytoplasmic membrane protein GO:0016020 BWK49_RS09875 6d6369b42ba17d52720ff21f5fe4d5cb 207 Pfam PF01323 DSBA-like thioredoxin domain 12 165 9.2E-10 T 06-07-2017 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 BWK49_RS09875 6d6369b42ba17d52720ff21f5fe4d5cb 207 Gene3D G3DSA:3.40.30.10 7 165 1.3E-12 T 06-07-2017 IPR012336 Thioredoxin-like fold BWK49_RS09875 6d6369b42ba17d52720ff21f5fe4d5cb 207 SUPERFAMILY SSF52833 9 167 2.42E-22 T 06-07-2017 IPR012336 Thioredoxin-like fold BWK49_RS26640 5e1b94c226fc41678897ebcc92dff297 864 SUPERFAMILY SSF56014 645 819 1.44E-50 T 06-07-2017 BWK49_RS26640 5e1b94c226fc41678897ebcc92dff297 864 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 572 632 1.2E-10 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 BWK49_RS26640 5e1b94c226fc41678897ebcc92dff297 864 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 163 181 8.9E-16 T 06-07-2017 BWK49_RS26640 5e1b94c226fc41678897ebcc92dff297 864 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 280 302 8.9E-16 T 06-07-2017 BWK49_RS26640 5e1b94c226fc41678897ebcc92dff297 864 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 16 35 8.9E-16 T 06-07-2017 BWK49_RS26640 5e1b94c226fc41678897ebcc92dff297 864 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 112 130 8.9E-16 T 06-07-2017 BWK49_RS26640 5e1b94c226fc41678897ebcc92dff297 864 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 253 269 8.9E-16 T 06-07-2017 BWK49_RS26640 5e1b94c226fc41678897ebcc92dff297 864 PIRSF PIRSF037149 8 848 0.0 T 06-07-2017 IPR017121 Nitrite reductase [NAD(P)H], large subunit GO:0042128 BWK49_RS26640 5e1b94c226fc41678897ebcc92dff297 864 SUPERFAMILY SSF55124 515 653 9.45E-23 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 BWK49_RS26640 5e1b94c226fc41678897ebcc92dff297 864 Gene3D G3DSA:3.50.50.60 252 324 7.0E-7 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS26640 5e1b94c226fc41678897ebcc92dff297 864 PRINTS PR00397 Sirohaem Fe-binding site signature 648 666 1.2E-5 T 06-07-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 BWK49_RS26640 5e1b94c226fc41678897ebcc92dff297 864 PRINTS PR00397 Sirohaem Fe-binding site signature 691 709 1.2E-5 T 06-07-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 BWK49_RS26640 5e1b94c226fc41678897ebcc92dff297 864 Gene3D G3DSA:3.50.50.60 14 114 3.6E-22 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS26640 5e1b94c226fc41678897ebcc92dff297 864 Gene3D G3DSA:3.30.413.10 644 782 8.6E-35 T 06-07-2017 BWK49_RS26640 5e1b94c226fc41678897ebcc92dff297 864 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 691 707 - T 06-07-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 BWK49_RS26640 5e1b94c226fc41678897ebcc92dff297 864 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 644 782 4.0E-19 T 06-07-2017 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 BWK49_RS26640 5e1b94c226fc41678897ebcc92dff297 864 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 15 302 1.4E-47 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS26640 5e1b94c226fc41678897ebcc92dff297 864 SUPERFAMILY SSF51905 165 329 1.22E-24 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS26640 5e1b94c226fc41678897ebcc92dff297 864 SUPERFAMILY SSF51905 14 206 6.69E-38 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS26640 5e1b94c226fc41678897ebcc92dff297 864 Gene3D G3DSA:3.50.50.60 115 251 2.0E-38 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS26640 5e1b94c226fc41678897ebcc92dff297 864 TIGRFAM TIGR02374 nitri_red_nirB: nitrite reductase [NAD(P)H], large subunit 16 813 0.0 T 06-07-2017 IPR012744 Nitrite reductase [NAD(P)H] large subunit, NirB GO:0008942|GO:0042128|GO:0050660|GO:0050661|GO:0055114 BWK49_RS26640 5e1b94c226fc41678897ebcc92dff297 864 Pfam PF04324 BFD-like [2Fe-2S] binding domain 440 487 1.1E-9 T 06-07-2017 IPR007419 BFD-like [2Fe-2S]-binding domain BWK49_RS23935 101a6c54c55bce5825f12c15aad0a960 179 SUPERFAMILY SSF54211 55 179 4.93E-44 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold BWK49_RS23935 101a6c54c55bce5825f12c15aad0a960 179 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 50 179 32.471 T 06-07-2017 IPR023035 Ribosomal protein S9, bacterial/plastid BWK49_RS23935 101a6c54c55bce5825f12c15aad0a960 179 Pfam PF00380 Ribosomal protein S9/S16 59 179 4.1E-42 T 06-07-2017 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 BWK49_RS23935 101a6c54c55bce5825f12c15aad0a960 179 ProSitePatterns PS00360 Ribosomal protein S9 signature. 118 136 - T 06-07-2017 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 BWK49_RS23935 101a6c54c55bce5825f12c15aad0a960 179 Gene3D G3DSA:3.30.230.10 55 179 1.5E-47 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup BWK49_RS18470 b62f97f379cfca523ee172fb5f0e2429 1125 SUPERFAMILY SSF52440 2 132 1.87E-40 T 06-07-2017 IPR016185 Pre-ATP-grasp domain BWK49_RS18470 b62f97f379cfca523ee172fb5f0e2429 1125 SUPERFAMILY SSF48108 401 556 1.57E-38 T 06-07-2017 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 BWK49_RS18470 b62f97f379cfca523ee172fb5f0e2429 1125 SMART SM00851 989 1082 8.5E-28 T 06-07-2017 IPR011607 Methylglyoxal synthase-like domain BWK49_RS18470 b62f97f379cfca523ee172fb5f0e2429 1125 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 133 339 2.6E-65 T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 BWK49_RS18470 b62f97f379cfca523ee172fb5f0e2429 1125 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 692 894 2.0E-34 T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 BWK49_RS18470 b62f97f379cfca523ee172fb5f0e2429 1125 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 1.9E-60 T 06-07-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 BWK49_RS18470 b62f97f379cfca523ee172fb5f0e2429 1125 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 209 228 1.9E-60 T 06-07-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 BWK49_RS18470 b62f97f379cfca523ee172fb5f0e2429 1125 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 244 261 1.9E-60 T 06-07-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 BWK49_RS18470 b62f97f379cfca523ee172fb5f0e2429 1125 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 384 402 1.9E-60 T 06-07-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 BWK49_RS18470 b62f97f379cfca523ee172fb5f0e2429 1125 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 302 331 1.9E-60 T 06-07-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 BWK49_RS18470 b62f97f379cfca523ee172fb5f0e2429 1125 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 1.9E-60 T 06-07-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 BWK49_RS18470 b62f97f379cfca523ee172fb5f0e2429 1125 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 173 185 1.9E-60 T 06-07-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 BWK49_RS18470 b62f97f379cfca523ee172fb5f0e2429 1125 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 433 553 3.5E-35 T 06-07-2017 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 BWK49_RS18470 b62f97f379cfca523ee172fb5f0e2429 1125 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 728 742 - T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 BWK49_RS18470 b62f97f379cfca523ee172fb5f0e2429 1125 SUPERFAMILY SSF56059 133 405 9.02E-100 T 06-07-2017 BWK49_RS18470 b62f97f379cfca523ee172fb5f0e2429 1125 Gene3D G3DSA:3.30.470.20 207 404 9.3E-74 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 BWK49_RS18470 b62f97f379cfca523ee172fb5f0e2429 1125 Gene3D G3DSA:3.30.470.20 764 968 2.1E-68 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 BWK49_RS18470 b62f97f379cfca523ee172fb5f0e2429 1125 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1103 12.745 T 06-07-2017 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 BWK49_RS18470 b62f97f379cfca523ee172fb5f0e2429 1125 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 302 309 - T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 BWK49_RS18470 b62f97f379cfca523ee172fb5f0e2429 1125 SUPERFAMILY SSF56059 692 967 2.12E-95 T 06-07-2017 BWK49_RS18470 b62f97f379cfca523ee172fb5f0e2429 1125 SUPERFAMILY SSF52440 568 693 2.73E-43 T 06-07-2017 IPR016185 Pre-ATP-grasp domain BWK49_RS18470 b62f97f379cfca523ee172fb5f0e2429 1125 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 857 864 - T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 BWK49_RS18470 b62f97f379cfca523ee172fb5f0e2429 1125 Gene3D G3DSA:3.40.50.20 4 112 2.7E-37 T 06-07-2017 IPR016185 Pre-ATP-grasp domain BWK49_RS18470 b62f97f379cfca523ee172fb5f0e2429 1125 Gene3D G3DSA:3.40.50.20 543 681 1.5E-54 T 06-07-2017 IPR016185 Pre-ATP-grasp domain BWK49_RS18470 b62f97f379cfca523ee172fb5f0e2429 1125 SUPERFAMILY SSF52335 976 1112 2.62E-35 T 06-07-2017 IPR011607 Methylglyoxal synthase-like domain BWK49_RS18470 b62f97f379cfca523ee172fb5f0e2429 1125 Gene3D G3DSA:3.30.1490.20 148 206 7.6E-18 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 BWK49_RS18470 b62f97f379cfca523ee172fb5f0e2429 1125 Gene3D G3DSA:3.30.1490.20 705 763 8.2E-28 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 BWK49_RS18470 b62f97f379cfca523ee172fb5f0e2429 1125 Gene3D G3DSA:1.10.1030.10 405 542 2.9E-39 T 06-07-2017 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 BWK49_RS18470 b62f97f379cfca523ee172fb5f0e2429 1125 Gene3D G3DSA:3.40.50.1380 972 1114 1.0E-41 T 06-07-2017 IPR011607 Methylglyoxal synthase-like domain BWK49_RS18470 b62f97f379cfca523ee172fb5f0e2429 1125 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1092 0.0 T 06-07-2017 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 BWK49_RS18470 b62f97f379cfca523ee172fb5f0e2429 1125 SMART SM01096 430 553 4.3E-58 T 06-07-2017 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 BWK49_RS18470 b62f97f379cfca523ee172fb5f0e2429 1125 Pfam PF02142 MGS-like domain 990 1082 3.1E-23 T 06-07-2017 IPR011607 Methylglyoxal synthase-like domain BWK49_RS06635 0b4a26ad836c2116da3e977524d3db70 326 Pfam PF11228 Protein of unknown function (DUF3027) 51 240 1.1E-79 T 06-07-2017 IPR021391 Protein of unknown function DUF3027 BWK49_RS07680 23ac10917e597047a5c09661f5b68108 145 SUPERFAMILY SSF52821 13 120 1.31E-15 T 06-07-2017 IPR001763 Rhodanese-like domain BWK49_RS07680 23ac10917e597047a5c09661f5b68108 145 Gene3D G3DSA:3.40.250.10 8 120 2.0E-15 T 06-07-2017 IPR001763 Rhodanese-like domain BWK49_RS07680 23ac10917e597047a5c09661f5b68108 145 SMART SM00450 17 122 2.2E-10 T 06-07-2017 IPR001763 Rhodanese-like domain BWK49_RS07680 23ac10917e597047a5c09661f5b68108 145 Pfam PF00581 Rhodanese-like domain 21 116 5.7E-7 T 06-07-2017 IPR001763 Rhodanese-like domain BWK49_RS02945 fe0ae77d75e8174d869e6e94db85c0aa 410 SUPERFAMILY SSF52540 6 223 8.4E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS02945 fe0ae77d75e8174d869e6e94db85c0aa 410 Gene3D G3DSA:1.20.272.10 315 393 6.4E-6 T 06-07-2017 BWK49_RS02945 fe0ae77d75e8174d869e6e94db85c0aa 410 TIGRFAM TIGR00678 holB: DNA polymerase III, delta' subunit 36 219 1.5E-58 T 06-07-2017 IPR004622 DNA polymerase III, delta prime subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 BWK49_RS02945 fe0ae77d75e8174d869e6e94db85c0aa 410 Gene3D G3DSA:3.40.50.300 5 183 3.5E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS02945 fe0ae77d75e8174d869e6e94db85c0aa 410 SUPERFAMILY SSF48019 321 394 2.72E-6 T 06-07-2017 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 BWK49_RS02945 fe0ae77d75e8174d869e6e94db85c0aa 410 Pfam PF13177 DNA polymerase III, delta subunit 35 182 1.7E-34 T 06-07-2017 BWK49_RS02945 fe0ae77d75e8174d869e6e94db85c0aa 410 SMART SM00382 39 185 1.7E-4 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS18920 b3e7f6ffb3146875e41a2d2ba1f0717d 691 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 84 669 1.7E-193 T 06-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 BWK49_RS18920 b3e7f6ffb3146875e41a2d2ba1f0717d 691 SUPERFAMILY SSF55681 268 565 2.03E-92 T 06-07-2017 BWK49_RS18920 b3e7f6ffb3146875e41a2d2ba1f0717d 691 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 202 244 2.8E-12 T 06-07-2017 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 BWK49_RS18920 b3e7f6ffb3146875e41a2d2ba1f0717d 691 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 363 569 3.0E-38 T 06-07-2017 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 BWK49_RS18920 b3e7f6ffb3146875e41a2d2ba1f0717d 691 PRINTS PR01047 Threonyl-tRNA synthetase signature 401 424 4.9E-52 T 06-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 BWK49_RS18920 b3e7f6ffb3146875e41a2d2ba1f0717d 691 PRINTS PR01047 Threonyl-tRNA synthetase signature 547 560 4.9E-52 T 06-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 BWK49_RS18920 b3e7f6ffb3146875e41a2d2ba1f0717d 691 PRINTS PR01047 Threonyl-tRNA synthetase signature 574 586 4.9E-52 T 06-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 BWK49_RS18920 b3e7f6ffb3146875e41a2d2ba1f0717d 691 PRINTS PR01047 Threonyl-tRNA synthetase signature 368 396 4.9E-52 T 06-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 BWK49_RS18920 b3e7f6ffb3146875e41a2d2ba1f0717d 691 PRINTS PR01047 Threonyl-tRNA synthetase signature 504 532 4.9E-52 T 06-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 BWK49_RS18920 b3e7f6ffb3146875e41a2d2ba1f0717d 691 Gene3D G3DSA:3.30.54.20 146 212 6.2E-9 T 06-07-2017 BWK49_RS18920 b3e7f6ffb3146875e41a2d2ba1f0717d 691 Gene3D G3DSA:3.30.980.10 213 249 1.4E-41 T 06-07-2017 BWK49_RS18920 b3e7f6ffb3146875e41a2d2ba1f0717d 691 Gene3D G3DSA:3.30.980.10 78 141 1.4E-41 T 06-07-2017 BWK49_RS18920 b3e7f6ffb3146875e41a2d2ba1f0717d 691 Pfam PF03129 Anticodon binding domain 581 670 3.8E-15 T 06-07-2017 IPR004154 Anticodon-binding BWK49_RS18920 b3e7f6ffb3146875e41a2d2ba1f0717d 691 Gene3D G3DSA:3.40.50.800 571 677 1.4E-27 T 06-07-2017 IPR004154 Anticodon-binding BWK49_RS18920 b3e7f6ffb3146875e41a2d2ba1f0717d 691 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 78 674 33.697 T 06-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 BWK49_RS18920 b3e7f6ffb3146875e41a2d2ba1f0717d 691 SUPERFAMILY SSF55186 76 265 1.22E-52 T 06-07-2017 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 BWK49_RS18920 b3e7f6ffb3146875e41a2d2ba1f0717d 691 SMART SM00863 188 244 2.5E-17 T 06-07-2017 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 BWK49_RS18920 b3e7f6ffb3146875e41a2d2ba1f0717d 691 SUPERFAMILY SSF52954 569 677 1.37E-26 T 06-07-2017 IPR004154 Anticodon-binding BWK49_RS18920 b3e7f6ffb3146875e41a2d2ba1f0717d 691 Gene3D G3DSA:3.30.930.10 267 570 4.7E-105 T 06-07-2017 BWK49_RS25905 5563cd022e93c3b757236ed7b278d85d 762 SMART SM00220 163 405 1.9E-28 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 BWK49_RS25905 5563cd022e93c3b757236ed7b278d85d 762 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 284 296 - T 06-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 BWK49_RS25905 5563cd022e93c3b757236ed7b278d85d 762 Gene3D G3DSA:3.30.200.20 153 243 1.0E-14 T 06-07-2017 BWK49_RS25905 5563cd022e93c3b757236ed7b278d85d 762 Pfam PF16918 Protein kinase G tetratricopeptide repeat 421 760 1.1E-148 T 06-07-2017 IPR031636 Protein kinase G, tetratricopeptide repeat containing domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 BWK49_RS25905 5563cd022e93c3b757236ed7b278d85d 762 Pfam PF00069 Protein kinase domain 163 352 5.7E-32 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 BWK49_RS25905 5563cd022e93c3b757236ed7b278d85d 762 Pfam PF16919 Protein kinase G rubredoxin domain 23 162 3.9E-58 T 06-07-2017 IPR031634 Protein kinase G, rubredoxin domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 BWK49_RS25905 5563cd022e93c3b757236ed7b278d85d 762 Gene3D G3DSA:1.25.40.10 521 698 3.5E-6 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 BWK49_RS25905 5563cd022e93c3b757236ed7b278d85d 762 SUPERFAMILY SSF56112 146 405 1.43E-45 T 06-07-2017 IPR011009 Protein kinase-like domain BWK49_RS25905 5563cd022e93c3b757236ed7b278d85d 762 SUPERFAMILY SSF48452 522 697 2.15E-6 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 BWK49_RS25905 5563cd022e93c3b757236ed7b278d85d 762 Gene3D G3DSA:1.10.510.10 244 351 8.4E-25 T 06-07-2017 BWK49_RS09070 4f4ac3fa76700042f841c3a621d65cd8 397 SUPERFAMILY SSF53901 276 394 9.87E-35 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS09070 4f4ac3fa76700042f841c3a621d65cd8 397 Pfam PF02803 Thiolase, C-terminal domain 275 395 2.3E-43 T 06-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 BWK49_RS09070 4f4ac3fa76700042f841c3a621d65cd8 397 SUPERFAMILY SSF53901 5 274 3.01E-80 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS09070 4f4ac3fa76700042f841c3a621d65cd8 397 ProSitePatterns PS00099 Thiolases active site. 378 391 - T 06-07-2017 IPR020610 Thiolase, active site GO:0008152|GO:0016747 BWK49_RS09070 4f4ac3fa76700042f841c3a621d65cd8 397 Gene3D G3DSA:3.40.47.10 281 394 1.0E-51 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS09070 4f4ac3fa76700042f841c3a621d65cd8 397 Gene3D G3DSA:3.40.47.10 146 197 1.0E-51 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS09070 4f4ac3fa76700042f841c3a621d65cd8 397 Gene3D G3DSA:3.40.47.10 198 280 1.8E-67 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS09070 4f4ac3fa76700042f841c3a621d65cd8 397 Gene3D G3DSA:3.40.47.10 5 127 1.8E-67 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS09070 4f4ac3fa76700042f841c3a621d65cd8 397 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 394 5.5E-135 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 BWK49_RS09070 4f4ac3fa76700042f841c3a621d65cd8 397 Pfam PF00108 Thiolase, N-terminal domain 5 266 1.4E-95 T 06-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 BWK49_RS09070 4f4ac3fa76700042f841c3a621d65cd8 397 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 88 106 - T 06-07-2017 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 BWK49_RS09070 4f4ac3fa76700042f841c3a621d65cd8 397 PIRSF PIRSF000429 1 397 8.0E-110 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 BWK49_RS09070 4f4ac3fa76700042f841c3a621d65cd8 397 ProSitePatterns PS00737 Thiolases signature 2. 343 359 - T 06-07-2017 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 BWK49_RS15320 6f43ae4dc6a16a6d3d88043efbfbec13 148 Pfam PF13577 SnoaL-like domain 2 127 1.3E-18 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain BWK49_RS15320 6f43ae4dc6a16a6d3d88043efbfbec13 148 Gene3D G3DSA:3.10.450.50 2 132 8.3E-21 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS15320 6f43ae4dc6a16a6d3d88043efbfbec13 148 SUPERFAMILY SSF54427 2 134 1.34E-21 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS21765 010d187517d180c28476d03a14043f31 845 SUPERFAMILY SSF49879 15 97 9.56E-13 T 06-07-2017 IPR008984 SMAD/FHA domain GO:0005515 BWK49_RS21765 010d187517d180c28476d03a14043f31 845 ProSitePatterns PS00211 ABC transporters family signature. 434 448 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 BWK49_RS21765 010d187517d180c28476d03a14043f31 845 SUPERFAMILY SSF52540 296 532 2.61E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS21765 010d187517d180c28476d03a14043f31 845 Gene3D G3DSA:3.40.50.300 292 522 3.3E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS21765 010d187517d180c28476d03a14043f31 845 Pfam PF00498 FHA domain 27 85 5.7E-8 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 BWK49_RS21765 010d187517d180c28476d03a14043f31 845 Pfam PF00498 FHA domain 214 276 3.1E-14 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 BWK49_RS21765 010d187517d180c28476d03a14043f31 845 Gene3D G3DSA:2.60.200.20 165 289 1.4E-18 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 BWK49_RS21765 010d187517d180c28476d03a14043f31 845 Pfam PF00005 ABC transporter 316 462 2.6E-32 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 BWK49_RS21765 010d187517d180c28476d03a14043f31 845 SMART SM00382 324 493 1.3E-8 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS21765 010d187517d180c28476d03a14043f31 845 SMART SM00240 25 75 3.2E-6 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 BWK49_RS21765 010d187517d180c28476d03a14043f31 845 SMART SM00240 212 262 1.0E-10 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 BWK49_RS21765 010d187517d180c28476d03a14043f31 845 Gene3D G3DSA:2.60.200.20 17 89 8.3E-11 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 BWK49_RS21765 010d187517d180c28476d03a14043f31 845 Pfam PF01061 ABC-2 type transporter 576 789 1.3E-21 T 06-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 BWK49_RS21765 010d187517d180c28476d03a14043f31 845 SUPERFAMILY SSF49879 142 283 3.25E-22 T 06-07-2017 IPR008984 SMAD/FHA domain GO:0005515 BWK49_RS25670 a959d431ffd28e338e2093459f6c9937 723 SUPERFAMILY SSF52540 211 446 1.31E-26 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS25670 a959d431ffd28e338e2093459f6c9937 723 Gene3D G3DSA:1.10.8.60 640 709 3.8E-18 T 06-07-2017 BWK49_RS25670 a959d431ffd28e338e2093459f6c9937 723 Pfam PF02359 Cell division protein 48 (CDC48), N-terminal domain 20 92 1.2E-11 T 06-07-2017 IPR003338 CDC48, N-terminal subdomain BWK49_RS25670 a959d431ffd28e338e2093459f6c9937 723 Gene3D G3DSA:1.10.8.60 379 446 1.9E-14 T 06-07-2017 BWK49_RS25670 a959d431ffd28e338e2093459f6c9937 723 SUPERFAMILY SSF50692 20 91 8.7E-10 T 06-07-2017 IPR009010 Aspartate decarboxylase-like domain BWK49_RS25670 a959d431ffd28e338e2093459f6c9937 723 SMART SM00382 245 367 0.048 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS25670 a959d431ffd28e338e2093459f6c9937 723 SMART SM00382 496 633 7.8E-19 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS25670 a959d431ffd28e338e2093459f6c9937 723 SMART SM01072 110 192 3.7E-5 T 06-07-2017 IPR004201 CDC48, domain 2 BWK49_RS25670 a959d431ffd28e338e2093459f6c9937 723 ProSitePatterns PS00674 AAA-protein family signature. 601 619 - T 06-07-2017 IPR003960 ATPase, AAA-type, conserved site GO:0005524 BWK49_RS25670 a959d431ffd28e338e2093459f6c9937 723 Gene3D G3DSA:3.40.50.300 459 639 1.3E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS25670 a959d431ffd28e338e2093459f6c9937 723 Gene3D G3DSA:3.40.50.300 212 378 2.5E-20 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS25670 a959d431ffd28e338e2093459f6c9937 723 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 500 630 9.9E-40 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 BWK49_RS25670 a959d431ffd28e338e2093459f6c9937 723 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 249 368 2.8E-12 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 BWK49_RS25670 a959d431ffd28e338e2093459f6c9937 723 SUPERFAMILY SSF52540 459 715 6.38E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS25670 a959d431ffd28e338e2093459f6c9937 723 Gene3D G3DSA:2.40.40.20 18 91 1.3E-7 T 06-07-2017 BWK49_RS25670 a959d431ffd28e338e2093459f6c9937 723 SMART SM01073 9 93 1.4E-14 T 06-07-2017 IPR003338 CDC48, N-terminal subdomain BWK49_RS24615 4df7400e9b163a8dccfceb7c8c75815f 159 PIRSF PIRSF018072 2 150 3.7E-54 T 06-07-2017 IPR016709 Uncharacterised protein family UPF0336 BWK49_RS24615 4df7400e9b163a8dccfceb7c8c75815f 159 Hamap MF_00799 UPF0336 protein . 1 148 32.963 T 06-07-2017 IPR016709 Uncharacterised protein family UPF0336 BWK49_RS24615 4df7400e9b163a8dccfceb7c8c75815f 159 Gene3D G3DSA:3.10.129.10 10 148 6.9E-19 T 06-07-2017 IPR029069 HotDog domain BWK49_RS24615 4df7400e9b163a8dccfceb7c8c75815f 159 SUPERFAMILY SSF54637 7 149 1.29E-33 T 06-07-2017 IPR029069 HotDog domain BWK49_RS24615 4df7400e9b163a8dccfceb7c8c75815f 159 Pfam PF13452 N-terminal half of MaoC dehydratase 7 137 2.3E-29 T 06-07-2017 BWK49_RS14315 199dbf350ace1ad15272cf00e4fdd741 393 Gene3D G3DSA:3.40.50.2000 1 231 7.3E-47 T 06-07-2017 BWK49_RS14315 199dbf350ace1ad15272cf00e4fdd741 393 Gene3D G3DSA:3.40.50.2000 232 366 4.3E-6 T 06-07-2017 BWK49_RS14315 199dbf350ace1ad15272cf00e4fdd741 393 SUPERFAMILY SSF53756 1 389 6.67E-77 T 06-07-2017 BWK49_RS14315 199dbf350ace1ad15272cf00e4fdd741 393 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 226 360 1.7E-5 T 06-07-2017 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 BWK49_RS12840 de5cf03412335a17d4f15ebbbee864de 227 Pfam PF11241 Protein of unknown function (DUF3043) 39 223 5.1E-58 T 06-07-2017 IPR021403 Protein of unknown function DUF3043 BWK49_RS20940 1b61c3329e3b7f9b745877565ba1e477 168 SUPERFAMILY SSF55021 82 164 3.13E-26 T 06-07-2017 BWK49_RS20940 1b61c3329e3b7f9b745877565ba1e477 168 SUPERFAMILY SSF55021 6 78 5.58E-23 T 06-07-2017 BWK49_RS20940 1b61c3329e3b7f9b745877565ba1e477 168 Gene3D G3DSA:3.30.70.1150 87 163 2.9E-29 T 06-07-2017 BWK49_RS20940 1b61c3329e3b7f9b745877565ba1e477 168 Pfam PF13710 ACT domain 14 76 7.7E-19 T 06-07-2017 BWK49_RS20940 1b61c3329e3b7f9b745877565ba1e477 168 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 1 79 5.0E-39 T 06-07-2017 BWK49_RS20940 1b61c3329e3b7f9b745877565ba1e477 168 Pfam PF10369 Small subunit of acetolactate synthase 87 160 3.2E-26 T 06-07-2017 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 BWK49_RS20940 1b61c3329e3b7f9b745877565ba1e477 168 Gene3D G3DSA:3.30.70.260 5 81 1.2E-35 T 06-07-2017 BWK49_RS20940 1b61c3329e3b7f9b745877565ba1e477 168 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 5 161 5.5E-62 T 06-07-2017 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 BWK49_RS09930 f588db2947ae57edd5f3b1e2fa776529 426 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 9 411 1.1E-195 T 06-07-2017 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 BWK49_RS09930 f588db2947ae57edd5f3b1e2fa776529 426 Gene3D G3DSA:3.40.50.300 294 311 1.8E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS09930 f588db2947ae57edd5f3b1e2fa776529 426 Gene3D G3DSA:3.40.50.300 63 255 1.8E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS09930 f588db2947ae57edd5f3b1e2fa776529 426 Pfam PF07724 AAA domain (Cdc48 subfamily) 114 310 2.5E-50 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 BWK49_RS09930 f588db2947ae57edd5f3b1e2fa776529 426 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 317 395 8.2E-17 T 06-07-2017 IPR019489 Clp ATPase, C-terminal BWK49_RS09930 f588db2947ae57edd5f3b1e2fa776529 426 SMART SM00382 113 266 1.7E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS09930 f588db2947ae57edd5f3b1e2fa776529 426 SUPERFAMILY SSF52540 59 404 6.87E-76 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS09930 f588db2947ae57edd5f3b1e2fa776529 426 SUPERFAMILY SSF57716 11 46 1.37E-11 T 06-07-2017 BWK49_RS09930 f588db2947ae57edd5f3b1e2fa776529 426 Pfam PF06689 ClpX C4-type zinc finger 11 48 8.9E-21 T 06-07-2017 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 BWK49_RS09930 f588db2947ae57edd5f3b1e2fa776529 426 SMART SM01086 317 407 9.0E-33 T 06-07-2017 IPR019489 Clp ATPase, C-terminal BWK49_RS09930 f588db2947ae57edd5f3b1e2fa776529 426 SMART SM00994 10 49 1.1E-23 T 06-07-2017 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 BWK49_RS09930 f588db2947ae57edd5f3b1e2fa776529 426 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 2 415 52.793 T 06-07-2017 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 BWK49_RS09930 f588db2947ae57edd5f3b1e2fa776529 426 Gene3D G3DSA:1.10.8.60 316 416 9.7E-37 T 06-07-2017 BWK49_RS11025 628236db4cff4b21d1e539ded23f67a3 201 Gene3D G3DSA:3.40.50.720 51 199 7.6E-17 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS11025 628236db4cff4b21d1e539ded23f67a3 201 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 43 196 6.9E-14 T 06-07-2017 BWK49_RS11025 628236db4cff4b21d1e539ded23f67a3 201 SUPERFAMILY SSF51735 45 199 2.44E-16 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS28025 45793113e2ae659e48e61743c27c600d 291 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 42 287 1.9E-45 T 06-07-2017 BWK49_RS28025 45793113e2ae659e48e61743c27c600d 291 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 113 124 3.6E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS28025 45793113e2ae659e48e61743c27c600d 291 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 166 174 3.6E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS28025 45793113e2ae659e48e61743c27c600d 291 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 186 205 3.6E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS28025 45793113e2ae659e48e61743c27c600d 291 Gene3D G3DSA:3.40.50.720 28 290 1.0E-65 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS28025 45793113e2ae659e48e61743c27c600d 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 186 205 1.2E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS28025 45793113e2ae659e48e61743c27c600d 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 176 1.2E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS28025 45793113e2ae659e48e61743c27c600d 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 224 1.2E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS28025 45793113e2ae659e48e61743c27c600d 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 113 124 1.2E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS28025 45793113e2ae659e48e61743c27c600d 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 38 55 1.2E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS28025 45793113e2ae659e48e61743c27c600d 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 252 272 1.2E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS28025 45793113e2ae659e48e61743c27c600d 291 SUPERFAMILY SSF51735 25 290 1.02E-63 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS28025 45793113e2ae659e48e61743c27c600d 291 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 173 201 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS22110 4b14bc0dc59e7cf7de52761fc6d83130 448 SUPERFAMILY SSF54373 291 394 1.64E-27 T 06-07-2017 BWK49_RS22110 4b14bc0dc59e7cf7de52761fc6d83130 448 PRINTS PR00757 Flavin-containing amine oxidase signature 175 196 3.4E-32 T 06-07-2017 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 BWK49_RS22110 4b14bc0dc59e7cf7de52761fc6d83130 448 PRINTS PR00757 Flavin-containing amine oxidase signature 294 313 3.4E-32 T 06-07-2017 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 BWK49_RS22110 4b14bc0dc59e7cf7de52761fc6d83130 448 PRINTS PR00757 Flavin-containing amine oxidase signature 9 28 3.4E-32 T 06-07-2017 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 BWK49_RS22110 4b14bc0dc59e7cf7de52761fc6d83130 448 PRINTS PR00757 Flavin-containing amine oxidase signature 374 393 3.4E-32 T 06-07-2017 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 BWK49_RS22110 4b14bc0dc59e7cf7de52761fc6d83130 448 PRINTS PR00757 Flavin-containing amine oxidase signature 198 220 3.4E-32 T 06-07-2017 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 BWK49_RS22110 4b14bc0dc59e7cf7de52761fc6d83130 448 PRINTS PR00757 Flavin-containing amine oxidase signature 426 443 3.4E-32 T 06-07-2017 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 BWK49_RS22110 4b14bc0dc59e7cf7de52761fc6d83130 448 PRINTS PR00757 Flavin-containing amine oxidase signature 395 417 3.4E-32 T 06-07-2017 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 BWK49_RS22110 4b14bc0dc59e7cf7de52761fc6d83130 448 Gene3D G3DSA:3.90.660.10 228 394 5.0E-48 T 06-07-2017 BWK49_RS22110 4b14bc0dc59e7cf7de52761fc6d83130 448 Gene3D G3DSA:1.10.405.10 111 200 4.4E-27 T 06-07-2017 BWK49_RS22110 4b14bc0dc59e7cf7de52761fc6d83130 448 Pfam PF01593 Flavin containing amine oxidoreductase 17 444 4.4E-73 T 06-07-2017 IPR002937 Amine oxidase GO:0016491|GO:0055114 BWK49_RS22110 4b14bc0dc59e7cf7de52761fc6d83130 448 SUPERFAMILY SSF51905 8 309 4.92E-68 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS22110 4b14bc0dc59e7cf7de52761fc6d83130 448 SUPERFAMILY SSF51905 408 446 4.92E-68 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS22110 4b14bc0dc59e7cf7de52761fc6d83130 448 Gene3D G3DSA:3.40.50.720 9 49 4.2E-13 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS02480 cc8df4abbdd1d31316a66819b54b014e 145 PIRSF PIRSF017371 1 145 7.2E-82 T 06-07-2017 IPR014488 Uncharacterised conserved protein UCP017371 BWK49_RS02480 cc8df4abbdd1d31316a66819b54b014e 145 SUPERFAMILY SSF55961 5 133 5.76E-13 T 06-07-2017 BWK49_RS02480 cc8df4abbdd1d31316a66819b54b014e 145 Gene3D G3DSA:3.30.530.20 8 144 3.5E-6 T 06-07-2017 IPR023393 START-like domain BWK49_RS02480 cc8df4abbdd1d31316a66819b54b014e 145 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 4 144 1.1E-22 T 06-07-2017 IPR019587 Polyketide cyclase/dehydrase BWK49_RS00135 4c820f0739c36b9465605fb241cf43c1 542 SMART SM00240 469 519 2.4E-12 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 BWK49_RS00135 4c820f0739c36b9465605fb241cf43c1 542 Pfam PF00498 FHA domain 471 533 1.6E-16 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 BWK49_RS00135 4c820f0739c36b9465605fb241cf43c1 542 Gene3D G3DSA:2.60.200.20 447 540 6.3E-27 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 BWK49_RS00135 4c820f0739c36b9465605fb241cf43c1 542 Pfam PF12401 Protein of unknown function (DUF2662) 10 121 8.6E-34 T 06-07-2017 IPR022128 Protein of unknown function DUF3662 BWK49_RS00135 4c820f0739c36b9465605fb241cf43c1 542 SUPERFAMILY SSF49879 426 541 1.05E-28 T 06-07-2017 IPR008984 SMAD/FHA domain GO:0005515 BWK49_RS24510 701c629637236e55b99c6fc2700ee75a 130 Gene3D G3DSA:3.30.1390.10 57 130 3.3E-31 T 06-07-2017 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like BWK49_RS24510 701c629637236e55b99c6fc2700ee75a 130 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 130 1.9E-50 T 06-07-2017 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS24510 701c629637236e55b99c6fc2700ee75a 130 SUPERFAMILY SSF48300 5 65 7.72E-15 T 06-07-2017 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS24510 701c629637236e55b99c6fc2700ee75a 130 SUPERFAMILY SSF54736 58 130 5.76E-22 T 06-07-2017 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like BWK49_RS24510 701c629637236e55b99c6fc2700ee75a 130 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 3 130 24.169 T 06-07-2017 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS24510 701c629637236e55b99c6fc2700ee75a 130 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 64 130 4.0E-16 T 06-07-2017 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS24510 701c629637236e55b99c6fc2700ee75a 130 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 63 130 2.7E-28 T 06-07-2017 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS24510 701c629637236e55b99c6fc2700ee75a 130 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 6 52 4.9E-19 T 06-07-2017 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS24510 701c629637236e55b99c6fc2700ee75a 130 Gene3D G3DSA:1.20.5.710 3 52 7.2E-20 T 06-07-2017 BWK49_RS17815 fd2959ba58b9cc9fe1b897d76e9dfcb7 3425 SUPERFAMILY SSF52777 1032 1197 2.67E-23 T 06-07-2017 BWK49_RS17815 fd2959ba58b9cc9fe1b897d76e9dfcb7 3425 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2093 2104 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS17815 fd2959ba58b9cc9fe1b897d76e9dfcb7 3425 SUPERFAMILY SSF52777 1680 1920 8.78E-50 T 06-07-2017 BWK49_RS17815 fd2959ba58b9cc9fe1b897d76e9dfcb7 3425 Pfam PF00501 AMP-binding enzyme 465 851 9.1E-86 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS17815 fd2959ba58b9cc9fe1b897d76e9dfcb7 3425 Pfam PF00501 AMP-binding enzyme 1956 2354 6.1E-91 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS17815 fd2959ba58b9cc9fe1b897d76e9dfcb7 3425 SUPERFAMILY SSF52777 2720 2979 1.0E-22 T 06-07-2017 BWK49_RS17815 fd2959ba58b9cc9fe1b897d76e9dfcb7 3425 SUPERFAMILY SSF56801 1911 2471 7.59E-147 T 06-07-2017 BWK49_RS17815 fd2959ba58b9cc9fe1b897d76e9dfcb7 3425 SUPERFAMILY SSF56801 420 966 3.53E-143 T 06-07-2017 BWK49_RS17815 fd2959ba58b9cc9fe1b897d76e9dfcb7 3425 Pfam PF00550 Phosphopantetheine attachment site 957 1016 1.5E-9 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS17815 fd2959ba58b9cc9fe1b897d76e9dfcb7 3425 Pfam PF00550 Phosphopantetheine attachment site 2461 2520 8.6E-9 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS17815 fd2959ba58b9cc9fe1b897d76e9dfcb7 3425 ProSitePatterns PS00455 Putative AMP-binding domain signature. 604 615 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS17815 fd2959ba58b9cc9fe1b897d76e9dfcb7 3425 SUPERFAMILY SSF52777 1501 1695 6.97E-42 T 06-07-2017 BWK49_RS17815 fd2959ba58b9cc9fe1b897d76e9dfcb7 3425 SUPERFAMILY SSF47336 2450 2520 3.01E-15 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS17815 fd2959ba58b9cc9fe1b897d76e9dfcb7 3425 Gene3D G3DSA:3.40.50.980 460 609 2.1E-46 T 06-07-2017 BWK49_RS17815 fd2959ba58b9cc9fe1b897d76e9dfcb7 3425 SUPERFAMILY SSF52777 3008 3201 1.05E-38 T 06-07-2017 BWK49_RS17815 fd2959ba58b9cc9fe1b897d76e9dfcb7 3425 Gene3D G3DSA:1.10.1200.10 958 1019 1.1E-24 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS17815 fd2959ba58b9cc9fe1b897d76e9dfcb7 3425 Gene3D G3DSA:1.10.1200.10 2463 2522 3.2E-23 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS17815 fd2959ba58b9cc9fe1b897d76e9dfcb7 3425 SUPERFAMILY SSF52777 2537 2702 3.11E-23 T 06-07-2017 BWK49_RS17815 fd2959ba58b9cc9fe1b897d76e9dfcb7 3425 SUPERFAMILY SSF52777 1225 1474 5.63E-24 T 06-07-2017 BWK49_RS17815 fd2959ba58b9cc9fe1b897d76e9dfcb7 3425 Pfam PF00668 Condensation domain 8 300 2.4E-29 T 06-07-2017 IPR001242 Condensation domain BWK49_RS17815 fd2959ba58b9cc9fe1b897d76e9dfcb7 3425 Pfam PF00668 Condensation domain 1505 1790 1.0E-53 T 06-07-2017 IPR001242 Condensation domain BWK49_RS17815 fd2959ba58b9cc9fe1b897d76e9dfcb7 3425 Pfam PF00668 Condensation domain 3011 3299 4.7E-53 T 06-07-2017 IPR001242 Condensation domain BWK49_RS17815 fd2959ba58b9cc9fe1b897d76e9dfcb7 3425 Pfam PF00668 Condensation domain 1053 1326 1.2E-19 T 06-07-2017 IPR001242 Condensation domain BWK49_RS17815 fd2959ba58b9cc9fe1b897d76e9dfcb7 3425 Pfam PF00668 Condensation domain 2557 2827 3.8E-24 T 06-07-2017 IPR001242 Condensation domain BWK49_RS17815 fd2959ba58b9cc9fe1b897d76e9dfcb7 3425 ProSitePatterns PS00012 Phosphopantetheine attachment site. 978 993 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site BWK49_RS17815 fd2959ba58b9cc9fe1b897d76e9dfcb7 3425 Gene3D G3DSA:3.30.300.30 846 957 2.5E-36 T 06-07-2017 BWK49_RS17815 fd2959ba58b9cc9fe1b897d76e9dfcb7 3425 Gene3D G3DSA:3.30.300.30 2349 2462 5.1E-37 T 06-07-2017 BWK49_RS17815 fd2959ba58b9cc9fe1b897d76e9dfcb7 3425 SUPERFAMILY SSF52777 190 434 2.67E-27 T 06-07-2017 BWK49_RS17815 fd2959ba58b9cc9fe1b897d76e9dfcb7 3425 SUPERFAMILY SSF52777 10 183 3.56E-28 T 06-07-2017 BWK49_RS17815 fd2959ba58b9cc9fe1b897d76e9dfcb7 3425 Gene3D G3DSA:2.30.38.10 2264 2344 7.6E-20 T 06-07-2017 BWK49_RS17815 fd2959ba58b9cc9fe1b897d76e9dfcb7 3425 Gene3D G3DSA:2.30.38.10 763 839 1.6E-21 T 06-07-2017 BWK49_RS17815 fd2959ba58b9cc9fe1b897d76e9dfcb7 3425 Pfam PF13193 AMP-binding enzyme C-terminal domain 859 930 5.6E-10 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS17815 fd2959ba58b9cc9fe1b897d76e9dfcb7 3425 Pfam PF13193 AMP-binding enzyme C-terminal domain 2362 2433 1.9E-9 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS17815 fd2959ba58b9cc9fe1b897d76e9dfcb7 3425 SUPERFAMILY SSF52777 3186 3422 2.89E-54 T 06-07-2017 BWK49_RS17815 fd2959ba58b9cc9fe1b897d76e9dfcb7 3425 SMART SM00823 Phosphopantetheine attachment site 954 1022 0.043 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS17815 fd2959ba58b9cc9fe1b897d76e9dfcb7 3425 SMART SM00823 Phosphopantetheine attachment site 2458 2526 0.18 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS17815 fd2959ba58b9cc9fe1b897d76e9dfcb7 3425 Gene3D G3DSA:3.40.50.980 2103 2254 1.8E-41 T 06-07-2017 BWK49_RS17815 fd2959ba58b9cc9fe1b897d76e9dfcb7 3425 Gene3D G3DSA:3.40.50.980 610 762 5.5E-36 T 06-07-2017 BWK49_RS17815 fd2959ba58b9cc9fe1b897d76e9dfcb7 3425 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 1341 1497 1.9E-32 T 06-07-2017 IPR010060 Non-ribosomal peptide synthase BWK49_RS17815 fd2959ba58b9cc9fe1b897d76e9dfcb7 3425 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 2847 3003 4.3E-34 T 06-07-2017 IPR010060 Non-ribosomal peptide synthase BWK49_RS17815 fd2959ba58b9cc9fe1b897d76e9dfcb7 3425 SUPERFAMILY SSF47336 946 1016 6.54E-16 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS17815 fd2959ba58b9cc9fe1b897d76e9dfcb7 3425 Gene3D G3DSA:3.40.50.980 1949 2102 1.2E-47 T 06-07-2017 BWK49_RS17815 fd2959ba58b9cc9fe1b897d76e9dfcb7 3425 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1975 2378 1.7E-131 T 06-07-2017 IPR010071 Amino acid adenylation domain BWK49_RS17815 fd2959ba58b9cc9fe1b897d76e9dfcb7 3425 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 486 875 4.1E-124 T 06-07-2017 IPR010071 Amino acid adenylation domain BWK49_RS17815 fd2959ba58b9cc9fe1b897d76e9dfcb7 3425 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2482 2497 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site BWK49_RS27605 9398ae3b106b84c7e13c8bb942ceff94 365 SUPERFAMILY SSF51679 50 365 1.53E-65 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS27605 9398ae3b106b84c7e13c8bb942ceff94 365 TIGRFAM TIGR04465 ArgArg_F420: TAT-translocated F420-dependent dehydrogenase, FGD2 family 2 365 2.2E-224 T 06-07-2017 IPR031017 TAT-translocated F420-dependent dehydrogenase, FGD2 family BWK49_RS27605 9398ae3b106b84c7e13c8bb942ceff94 365 Pfam PF00296 Luciferase-like monooxygenase 57 288 8.3E-56 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS27605 9398ae3b106b84c7e13c8bb942ceff94 365 Gene3D G3DSA:3.20.20.30 49 365 6.2E-74 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS27605 9398ae3b106b84c7e13c8bb942ceff94 365 TIGRFAM TIGR03557 F420_G6P_family: F420-dependent oxidoreductase, G6PDH family 49 365 2.9E-73 T 06-07-2017 IPR019945 F420-dependent glucose-6-phosphate dehydrogenase-related BWK49_RS18760 7320fe474ed6fbd83952a2d745821b29 420 Gene3D G3DSA:3.30.930.10 218 318 4.9E-86 T 06-07-2017 BWK49_RS18760 7320fe474ed6fbd83952a2d745821b29 420 Gene3D G3DSA:3.30.930.10 5 184 4.9E-86 T 06-07-2017 BWK49_RS18760 7320fe474ed6fbd83952a2d745821b29 420 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 6 406 9.1E-133 T 06-07-2017 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 BWK49_RS18760 7320fe474ed6fbd83952a2d745821b29 420 Pfam PF03129 Anticodon binding domain 328 412 5.0E-12 T 06-07-2017 IPR004154 Anticodon-binding BWK49_RS18760 7320fe474ed6fbd83952a2d745821b29 420 SUPERFAMILY SSF52954 324 418 3.11E-20 T 06-07-2017 IPR004154 Anticodon-binding BWK49_RS18760 7320fe474ed6fbd83952a2d745821b29 420 PIRSF PIRSF001549 1 418 1.8E-107 T 06-07-2017 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 BWK49_RS18760 7320fe474ed6fbd83952a2d745821b29 420 SUPERFAMILY SSF55681 5 313 1.88E-85 T 06-07-2017 BWK49_RS18760 7320fe474ed6fbd83952a2d745821b29 420 Pfam PF13393 Histidyl-tRNA synthetase 9 308 1.6E-43 T 06-07-2017 BWK49_RS18760 7320fe474ed6fbd83952a2d745821b29 420 Gene3D G3DSA:3.40.50.800 324 414 3.5E-24 T 06-07-2017 IPR004154 Anticodon-binding BWK49_RS18760 7320fe474ed6fbd83952a2d745821b29 420 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 2 420 31.131 T 06-07-2017 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 BWK49_RS20825 a8c9a3e8523f44c8da94d58736f86f28 318 Pfam PF00586 AIR synthase related protein, N-terminal domain 38 147 5.5E-19 T 06-07-2017 IPR016188 PurM-like, N-terminal domain BWK49_RS20825 a8c9a3e8523f44c8da94d58736f86f28 318 PIRSF PIRSF005303 8 318 2.7E-104 T 06-07-2017 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 BWK49_RS20825 a8c9a3e8523f44c8da94d58736f86f28 318 Gene3D G3DSA:3.90.650.10 156 317 1.1E-40 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain BWK49_RS20825 a8c9a3e8523f44c8da94d58736f86f28 318 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 14 317 5.6E-85 T 06-07-2017 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 BWK49_RS20825 a8c9a3e8523f44c8da94d58736f86f28 318 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 13 315 29.565 T 06-07-2017 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 BWK49_RS20825 a8c9a3e8523f44c8da94d58736f86f28 318 SUPERFAMILY SSF56042 153 306 4.93E-29 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain BWK49_RS20825 a8c9a3e8523f44c8da94d58736f86f28 318 SUPERFAMILY SSF55326 10 147 6.45E-33 T 06-07-2017 BWK49_RS20825 a8c9a3e8523f44c8da94d58736f86f28 318 Gene3D G3DSA:3.30.1330.10 9 149 9.6E-43 T 06-07-2017 IPR016188 PurM-like, N-terminal domain BWK49_RS27825 fdad88ce92b56addd19d1dee9d00978d 509 Gene3D G3DSA:2.30.38.10 320 392 5.4E-21 T 06-07-2017 BWK49_RS27825 fdad88ce92b56addd19d1dee9d00978d 509 Pfam PF00501 AMP-binding enzyme 12 402 6.9E-78 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS27825 fdad88ce92b56addd19d1dee9d00978d 509 Gene3D G3DSA:3.30.300.30 397 494 8.7E-33 T 06-07-2017 BWK49_RS27825 fdad88ce92b56addd19d1dee9d00978d 509 Gene3D G3DSA:3.40.50.980 7 160 4.4E-31 T 06-07-2017 BWK49_RS27825 fdad88ce92b56addd19d1dee9d00978d 509 ProSitePatterns PS00455 Putative AMP-binding domain signature. 154 165 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS27825 fdad88ce92b56addd19d1dee9d00978d 509 Pfam PF13193 AMP-binding enzyme C-terminal domain 411 485 4.8E-22 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS27825 fdad88ce92b56addd19d1dee9d00978d 509 SUPERFAMILY SSF56801 6 497 4.19E-125 T 06-07-2017 BWK49_RS27825 fdad88ce92b56addd19d1dee9d00978d 509 Gene3D G3DSA:3.40.50.980 161 307 1.7E-27 T 06-07-2017 BWK49_RS08980 d61b6b60a7a335ab9fc97f75d9db710a 147 Pfam PF10739 Protein of unknown function (DUF2550) 11 139 3.6E-42 T 06-07-2017 IPR019675 Protein of unknown function DUF2550 BWK49_RS16900 7d50547c48a15b456cb804de1fb2f293 318 SMART SM00382 111 243 1.4E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS16900 7d50547c48a15b456cb804de1fb2f293 318 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 115 239 1.2E-29 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 BWK49_RS16900 7d50547c48a15b456cb804de1fb2f293 318 SUPERFAMILY SSF52540 70 300 1.26E-39 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS16900 7d50547c48a15b456cb804de1fb2f293 318 Gene3D G3DSA:3.40.50.300 73 255 3.3E-38 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS01590 bc3dc9b5cd2e9017f21247e96ccecf02 247 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 15 199 2.7E-33 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal BWK49_RS01590 bc3dc9b5cd2e9017f21247e96ccecf02 247 Gene3D G3DSA:3.40.225.10 11 227 6.7E-41 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal BWK49_RS01590 bc3dc9b5cd2e9017f21247e96ccecf02 247 SUPERFAMILY SSF53639 10 222 4.12E-40 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal BWK49_RS01590 bc3dc9b5cd2e9017f21247e96ccecf02 247 SMART SM01007 13 202 1.0E-34 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal BWK49_RS07260 e652797df9559e6b92841acd382f5cc7 303 Gene3D G3DSA:1.10.10.10 109 167 1.2E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS07260 e652797df9559e6b92841acd382f5cc7 303 Pfam PF12680 SnoaL-like domain 184 279 3.6E-6 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain BWK49_RS07260 e652797df9559e6b92841acd382f5cc7 303 TIGRFAM TIGR02957 SigX4: RNA polymerase sigma-70 factor, TIGR02957 family 12 294 4.3E-101 T 06-07-2017 IPR014303 RNA polymerase sigma-70, ECF type BWK49_RS07260 e652797df9559e6b92841acd382f5cc7 303 Gene3D G3DSA:1.10.1740.10 16 90 6.0E-8 T 06-07-2017 BWK49_RS07260 e652797df9559e6b92841acd382f5cc7 303 SUPERFAMILY SSF54427 175 295 7.03E-19 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS07260 e652797df9559e6b92841acd382f5cc7 303 SUPERFAMILY SSF88659 88 168 8.6E-14 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS07260 e652797df9559e6b92841acd382f5cc7 303 Gene3D G3DSA:3.10.450.50 174 293 2.8E-16 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS07260 e652797df9559e6b92841acd382f5cc7 303 Pfam PF04542 Sigma-70 region 2 17 78 1.1E-9 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS07260 e652797df9559e6b92841acd382f5cc7 303 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 14 164 9.5E-18 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS07260 e652797df9559e6b92841acd382f5cc7 303 SUPERFAMILY SSF88946 13 96 1.65E-8 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS07260 e652797df9559e6b92841acd382f5cc7 303 Pfam PF08281 Sigma-70, region 4 111 162 5.7E-13 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS19865 c161ce87a2d742cf751e6b91199328ab 325 Gene3D G3DSA:3.60.21.10 18 117 7.4E-23 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like BWK49_RS19865 c161ce87a2d742cf751e6b91199328ab 325 Gene3D G3DSA:3.60.21.10 201 270 7.4E-23 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like BWK49_RS19865 c161ce87a2d742cf751e6b91199328ab 325 SUPERFAMILY SSF56300 17 269 7.91E-25 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like BWK49_RS19865 c161ce87a2d742cf751e6b91199328ab 325 Pfam PF00149 Calcineurin-like phosphoesterase 17 251 1.9E-12 T 06-07-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 BWK49_RS15675 5bfb5b088f17f0fd4b46baa460d783fb 377 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 243 364 2.4E-21 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS15675 5bfb5b088f17f0fd4b46baa460d783fb 377 SUPERFAMILY SSF47203 235 366 6.44E-31 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS15675 5bfb5b088f17f0fd4b46baa460d783fb 377 Gene3D G3DSA:1.20.140.10 231 364 3.3E-30 T 06-07-2017 BWK49_RS15675 5bfb5b088f17f0fd4b46baa460d783fb 377 SUPERFAMILY SSF56645 1 220 7.85E-36 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS15675 5bfb5b088f17f0fd4b46baa460d783fb 377 Gene3D G3DSA:1.10.540.10 5 119 4.4E-18 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS15675 5bfb5b088f17f0fd4b46baa460d783fb 377 Gene3D G3DSA:2.40.110.10 133 220 1.8E-11 T 06-07-2017 BWK49_RS15675 5bfb5b088f17f0fd4b46baa460d783fb 377 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 117 2.2E-17 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS17380 f146c0f0feb16835f67ad9ab6d017d40 345 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 246 334 3.8E-11 T 06-07-2017 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 BWK49_RS17380 f146c0f0feb16835f67ad9ab6d017d40 345 PIRSF PIRSF001619 16 343 9.7E-106 T 06-07-2017 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 BWK49_RS17380 f146c0f0feb16835f67ad9ab6d017d40 345 Hamap MF_01694 Biotin synthase [bioB]. 31 339 38.228 T 06-07-2017 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 BWK49_RS17380 f146c0f0feb16835f67ad9ab6d017d40 345 SUPERFAMILY SSF102114 31 325 6.02E-66 T 06-07-2017 BWK49_RS17380 f146c0f0feb16835f67ad9ab6d017d40 345 SMART SM00729 71 275 2.3E-34 T 06-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 BWK49_RS17380 f146c0f0feb16835f67ad9ab6d017d40 345 Gene3D G3DSA:3.20.20.70 32 336 7.5E-79 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 BWK49_RS17380 f146c0f0feb16835f67ad9ab6d017d40 345 TIGRFAM TIGR00433 bioB: biotin synthase 43 336 9.6E-107 T 06-07-2017 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 BWK49_RS17380 f146c0f0feb16835f67ad9ab6d017d40 345 SMART SM00876 246 338 7.6E-28 T 06-07-2017 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 BWK49_RS17380 f146c0f0feb16835f67ad9ab6d017d40 345 Pfam PF04055 Radical SAM superfamily 78 235 6.2E-14 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 BWK49_RS08015 2db1d6315801e4f2317de4c1b2408e78 471 Gene3D G3DSA:3.50.50.60 15 54 7.9E-11 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS08015 2db1d6315801e4f2317de4c1b2408e78 471 SUPERFAMILY SSF54373 301 404 4.12E-23 T 06-07-2017 BWK49_RS08015 2db1d6315801e4f2317de4c1b2408e78 471 Gene3D G3DSA:1.10.405.10 120 207 1.9E-23 T 06-07-2017 BWK49_RS08015 2db1d6315801e4f2317de4c1b2408e78 471 Pfam PF01593 Flavin containing amine oxidoreductase 25 457 9.4E-63 T 06-07-2017 IPR002937 Amine oxidase GO:0016491|GO:0055114 BWK49_RS08015 2db1d6315801e4f2317de4c1b2408e78 471 Gene3D G3DSA:3.90.660.10 237 405 6.4E-45 T 06-07-2017 BWK49_RS08015 2db1d6315801e4f2317de4c1b2408e78 471 PRINTS PR00757 Flavin-containing amine oxidase signature 17 36 1.1E-29 T 06-07-2017 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 BWK49_RS08015 2db1d6315801e4f2317de4c1b2408e78 471 PRINTS PR00757 Flavin-containing amine oxidase signature 208 230 1.1E-29 T 06-07-2017 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 BWK49_RS08015 2db1d6315801e4f2317de4c1b2408e78 471 PRINTS PR00757 Flavin-containing amine oxidase signature 387 406 1.1E-29 T 06-07-2017 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 BWK49_RS08015 2db1d6315801e4f2317de4c1b2408e78 471 PRINTS PR00757 Flavin-containing amine oxidase signature 439 456 1.1E-29 T 06-07-2017 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 BWK49_RS08015 2db1d6315801e4f2317de4c1b2408e78 471 PRINTS PR00757 Flavin-containing amine oxidase signature 304 323 1.1E-29 T 06-07-2017 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 BWK49_RS08015 2db1d6315801e4f2317de4c1b2408e78 471 PRINTS PR00757 Flavin-containing amine oxidase signature 103 125 1.1E-29 T 06-07-2017 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 BWK49_RS08015 2db1d6315801e4f2317de4c1b2408e78 471 PRINTS PR00757 Flavin-containing amine oxidase signature 185 206 1.1E-29 T 06-07-2017 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 BWK49_RS08015 2db1d6315801e4f2317de4c1b2408e78 471 PRINTS PR00757 Flavin-containing amine oxidase signature 408 430 1.1E-29 T 06-07-2017 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 BWK49_RS08015 2db1d6315801e4f2317de4c1b2408e78 471 SUPERFAMILY SSF51905 421 458 6.04E-68 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS08015 2db1d6315801e4f2317de4c1b2408e78 471 SUPERFAMILY SSF51905 13 319 6.04E-68 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS10810 e49301c63bfe583c03c1197f19c077ea 354 Gene3D G3DSA:3.40.50.720 4 140 1.1E-14 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS10810 e49301c63bfe583c03c1197f19c077ea 354 SUPERFAMILY SSF51735 1 102 5.42E-6 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS18525 30c7af32ec1edea4285f4f7191160009 462 Gene3D G3DSA:3.40.190.10 138 258 6.8E-14 T 06-07-2017 BWK49_RS18525 30c7af32ec1edea4285f4f7191160009 462 Pfam PF09084 NMT1/THI5 like 123 272 4.4E-9 T 06-07-2017 IPR015168 SsuA/THI5-like BWK49_RS18525 30c7af32ec1edea4285f4f7191160009 462 SUPERFAMILY SSF53850 60 321 1.66E-30 T 06-07-2017 BWK49_RS05855 b5704d23f1af3d95386a8548c76a2256 379 Pfam PF02803 Thiolase, C-terminal domain 255 375 9.5E-45 T 06-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 BWK49_RS05855 b5704d23f1af3d95386a8548c76a2256 379 Gene3D G3DSA:3.40.47.10 185 251 1.2E-44 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS05855 b5704d23f1af3d95386a8548c76a2256 379 Gene3D G3DSA:3.40.47.10 4 119 1.2E-44 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS05855 b5704d23f1af3d95386a8548c76a2256 379 ProSitePatterns PS00099 Thiolases active site. 358 371 - T 06-07-2017 IPR020610 Thiolase, active site GO:0008152|GO:0016747 BWK49_RS05855 b5704d23f1af3d95386a8548c76a2256 379 Pfam PF00108 Thiolase, N-terminal domain 5 249 5.4E-47 T 06-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 BWK49_RS05855 b5704d23f1af3d95386a8548c76a2256 379 SUPERFAMILY SSF53901 2 250 2.16E-53 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS05855 b5704d23f1af3d95386a8548c76a2256 379 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 375 4.2E-110 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 BWK49_RS05855 b5704d23f1af3d95386a8548c76a2256 379 SUPERFAMILY SSF53901 257 376 4.07E-42 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS05855 b5704d23f1af3d95386a8548c76a2256 379 Gene3D G3DSA:3.40.47.10 261 376 1.3E-59 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS05855 b5704d23f1af3d95386a8548c76a2256 379 Gene3D G3DSA:3.40.47.10 148 184 1.3E-59 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS05855 b5704d23f1af3d95386a8548c76a2256 379 PIRSF PIRSF000429 2 378 1.6E-103 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 BWK49_RS19465 8a9064601fb47fd7163ca1687c6097cb 229 SUPERFAMILY SSF47979 65 134 3.4E-27 T 06-07-2017 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 BWK49_RS19465 8a9064601fb47fd7163ca1687c6097cb 229 Gene3D G3DSA:1.10.10.10 2 72 3.7E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS19465 8a9064601fb47fd7163ca1687c6097cb 229 Gene3D G3DSA:2.30.30.90 151 229 8.1E-31 T 06-07-2017 BWK49_RS19465 8a9064601fb47fd7163ca1687c6097cb 229 SMART SM00899 152 228 7.9E-11 T 06-07-2017 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 BWK49_RS19465 8a9064601fb47fd7163ca1687c6097cb 229 SUPERFAMILY SSF50037 130 229 3.2E-23 T 06-07-2017 IPR008988 Transcriptional repressor, C-terminal BWK49_RS19465 8a9064601fb47fd7163ca1687c6097cb 229 SMART SM00529 26 125 9.3E-49 T 06-07-2017 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 BWK49_RS19465 8a9064601fb47fd7163ca1687c6097cb 229 Gene3D G3DSA:1.10.60.10 75 134 1.2E-31 T 06-07-2017 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 BWK49_RS19465 8a9064601fb47fd7163ca1687c6097cb 229 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 3 62 6.5E-22 T 06-07-2017 IPR022687 DTXR-type HTH domain GO:0003677 BWK49_RS19465 8a9064601fb47fd7163ca1687c6097cb 229 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 65 133 5.0E-30 T 06-07-2017 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 BWK49_RS19465 8a9064601fb47fd7163ca1687c6097cb 229 SUPERFAMILY SSF46785 2 62 9.24E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS19465 8a9064601fb47fd7163ca1687c6097cb 229 Pfam PF04023 FeoA domain 152 227 3.9E-9 T 06-07-2017 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 BWK49_RS09310 ab461855d1d05bd918128ad0c8b3b18c 350 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 197 327 1.0E-15 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS09310 ab461855d1d05bd918128ad0c8b3b18c 350 SUPERFAMILY SSF56645 10 122 4.19E-17 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS09310 ab461855d1d05bd918128ad0c8b3b18c 350 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 14 110 2.1E-14 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS09310 ab461855d1d05bd918128ad0c8b3b18c 350 Gene3D G3DSA:1.20.140.10 198 337 1.8E-22 T 06-07-2017 BWK49_RS09310 ab461855d1d05bd918128ad0c8b3b18c 350 SUPERFAMILY SSF47203 197 337 1.48E-24 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS09310 ab461855d1d05bd918128ad0c8b3b18c 350 Gene3D G3DSA:1.10.540.10 10 108 5.5E-16 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS12490 00c2a5cbd213c20bc136b7cbb3fba472 153 Pfam PF00578 AhpC/TSA family 4 129 3.9E-34 T 06-07-2017 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 BWK49_RS12490 00c2a5cbd213c20bc136b7cbb3fba472 153 PIRSF PIRSF000239 1 152 2.4E-23 T 06-07-2017 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 BWK49_RS12490 00c2a5cbd213c20bc136b7cbb3fba472 153 SUPERFAMILY SSF52833 1 152 1.21E-38 T 06-07-2017 IPR012336 Thioredoxin-like fold BWK49_RS12490 00c2a5cbd213c20bc136b7cbb3fba472 153 Gene3D G3DSA:3.40.30.10 1 151 2.2E-41 T 06-07-2017 IPR012336 Thioredoxin-like fold BWK49_RS21820 20413cc444a7848a22caf5635bc3e062 169 Gene3D G3DSA:2.40.280.10 20 139 4.1E-50 T 06-07-2017 IPR023620 Small protein B BWK49_RS21820 20413cc444a7848a22caf5635bc3e062 169 ProSitePatterns PS01317 SsrA-binding protein. 39 51 - T 06-07-2017 IPR020081 SsrA-binding protein, conserved site BWK49_RS21820 20413cc444a7848a22caf5635bc3e062 169 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 21 144 1.0E-66 T 06-07-2017 IPR000037 SsrA-binding protein GO:0003723 BWK49_RS21820 20413cc444a7848a22caf5635bc3e062 169 Pfam PF01668 SmpB protein 20 84 1.7E-29 T 06-07-2017 IPR000037 SsrA-binding protein GO:0003723 BWK49_RS21820 20413cc444a7848a22caf5635bc3e062 169 TIGRFAM TIGR00086 smpB: SsrA-binding protein 21 161 2.5E-58 T 06-07-2017 IPR000037 SsrA-binding protein GO:0003723 BWK49_RS21820 20413cc444a7848a22caf5635bc3e062 169 SUPERFAMILY SSF74982 17 144 1.96E-49 T 06-07-2017 IPR023620 Small protein B BWK49_RS21820 20413cc444a7848a22caf5635bc3e062 169 Hamap MF_00023 SsrA-binding protein [smpB]. 1 167 66.09 T 06-07-2017 IPR000037 SsrA-binding protein GO:0003723 BWK49_RS10985 afb235f307a47df3bd5f4cf801870dd9 366 SUPERFAMILY SSF56645 3 212 2.09E-30 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS10985 afb235f307a47df3bd5f4cf801870dd9 366 SUPERFAMILY SSF47203 228 362 5.96E-38 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS10985 afb235f307a47df3bd5f4cf801870dd9 366 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 4 115 1.5E-14 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS10985 afb235f307a47df3bd5f4cf801870dd9 366 Gene3D G3DSA:1.20.140.10 206 363 2.9E-36 T 06-07-2017 BWK49_RS10985 afb235f307a47df3bd5f4cf801870dd9 366 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 233 360 7.3E-28 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS10985 afb235f307a47df3bd5f4cf801870dd9 366 Gene3D G3DSA:2.40.110.10 131 205 1.4E-4 T 06-07-2017 BWK49_RS10985 afb235f307a47df3bd5f4cf801870dd9 366 Gene3D G3DSA:1.10.540.10 3 116 1.1E-15 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS03835 ad7ec1a250c114b1c403befaeae340e9 1110 PRINTS PR00364 Disease resistance protein signature 311 325 5.4E-6 T 06-07-2017 BWK49_RS03835 ad7ec1a250c114b1c403befaeae340e9 1110 PRINTS PR00364 Disease resistance protein signature 406 420 5.4E-6 T 06-07-2017 BWK49_RS03835 ad7ec1a250c114b1c403befaeae340e9 1110 PRINTS PR00364 Disease resistance protein signature 242 257 5.4E-6 T 06-07-2017 BWK49_RS03835 ad7ec1a250c114b1c403befaeae340e9 1110 SMART SM00421 1050 1107 1.3E-22 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS03835 ad7ec1a250c114b1c403befaeae340e9 1110 SUPERFAMILY SSF55073 32 206 1.46E-37 T 06-07-2017 IPR029787 Nucleotide cyclase BWK49_RS03835 ad7ec1a250c114b1c403befaeae340e9 1110 SUPERFAMILY SSF46894 1045 1109 1.19E-17 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 BWK49_RS03835 ad7ec1a250c114b1c403befaeae340e9 1110 SUPERFAMILY SSF52540 215 470 1.09E-20 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS03835 ad7ec1a250c114b1c403befaeae340e9 1110 ProSitePatterns PS00622 LuxR-type HTH domain signature. 1067 1094 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS03835 ad7ec1a250c114b1c403befaeae340e9 1110 Gene3D G3DSA:3.40.50.300 217 266 1.8E-7 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS03835 ad7ec1a250c114b1c403befaeae340e9 1110 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 33 164 4.0E-9 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 BWK49_RS03835 ad7ec1a250c114b1c403befaeae340e9 1110 Gene3D G3DSA:1.25.40.10 698 994 6.0E-14 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 BWK49_RS03835 ad7ec1a250c114b1c403befaeae340e9 1110 Gene3D G3DSA:3.30.70.1230 32 206 5.0E-28 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 BWK49_RS03835 ad7ec1a250c114b1c403befaeae340e9 1110 Gene3D G3DSA:1.10.10.10 1040 1110 5.5E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS03835 ad7ec1a250c114b1c403befaeae340e9 1110 Pfam PF00196 Bacterial regulatory proteins, luxR family 1052 1106 3.9E-16 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS03835 ad7ec1a250c114b1c403befaeae340e9 1110 SMART SM00044 10 173 6.2E-4 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 BWK49_RS03835 ad7ec1a250c114b1c403befaeae340e9 1110 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 1067 1083 2.8E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS03835 ad7ec1a250c114b1c403befaeae340e9 1110 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 1083 1095 2.8E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS03835 ad7ec1a250c114b1c403befaeae340e9 1110 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 1053 1067 2.8E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS26650 23495af1e8a2cace427fbb36d26e9f7a 240 SUPERFAMILY SSF51621 2 238 3.59E-54 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 BWK49_RS26650 23495af1e8a2cace427fbb36d26e9f7a 240 Pfam PF13714 Phosphoenolpyruvate phosphomutase 2 234 1.2E-61 T 06-07-2017 BWK49_RS26650 23495af1e8a2cace427fbb36d26e9f7a 240 Gene3D G3DSA:3.20.20.60 2 221 7.3E-59 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 BWK49_RS10400 09ddac1d54f6ca4f8970ce9bfc710df3 86 SUPERFAMILY SSF47413 18 84 1.97E-15 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 BWK49_RS10400 09ddac1d54f6ca4f8970ce9bfc710df3 86 Gene3D G3DSA:1.10.260.40 16 84 3.8E-16 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 BWK49_RS10400 09ddac1d54f6ca4f8970ce9bfc710df3 86 SMART SM00530 26 81 4.5E-10 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 BWK49_RS10400 09ddac1d54f6ca4f8970ce9bfc710df3 86 Pfam PF01381 Helix-turn-helix 27 81 5.8E-10 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 BWK49_RS23695 a7fb7d3f129ba83629ecce0317027e21 334 SUPERFAMILY SSF51735 1 325 1.1E-53 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS23695 a7fb7d3f129ba83629ecce0317027e21 334 Gene3D G3DSA:3.90.25.10 223 325 4.4E-5 T 06-07-2017 BWK49_RS23695 a7fb7d3f129ba83629ecce0317027e21 334 Gene3D G3DSA:3.40.50.720 3 222 9.4E-42 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS23695 a7fb7d3f129ba83629ecce0317027e21 334 Pfam PF01370 NAD dependent epimerase/dehydratase family 5 231 1.5E-25 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 BWK49_RS13450 473d6235b969a3099c9703eae5ed65a0 926 Pfam PF08148 DSHCT (NUC185) domain 749 921 6.6E-38 T 06-07-2017 IPR012961 ATP-dependent RNA helicase Ski2, C-terminal BWK49_RS13450 473d6235b969a3099c9703eae5ed65a0 926 SUPERFAMILY SSF52540 350 443 7.17E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS13450 473d6235b969a3099c9703eae5ed65a0 926 SUPERFAMILY SSF52540 28 169 7.17E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS13450 473d6235b969a3099c9703eae5ed65a0 926 SUPERFAMILY SSF52540 264 308 7.17E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS13450 473d6235b969a3099c9703eae5ed65a0 926 SMART SM01142 745 926 5.5E-62 T 06-07-2017 IPR012961 ATP-dependent RNA helicase Ski2, C-terminal BWK49_RS13450 473d6235b969a3099c9703eae5ed65a0 926 SMART SM00487 14 196 2.3E-29 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain BWK49_RS13450 473d6235b969a3099c9703eae5ed65a0 926 Gene3D G3DSA:3.40.50.300 353 440 2.8E-17 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS13450 473d6235b969a3099c9703eae5ed65a0 926 Gene3D G3DSA:3.40.50.300 287 311 2.8E-17 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS13450 473d6235b969a3099c9703eae5ed65a0 926 Pfam PF00270 DEAD/DEAH box helicase 22 168 7.1E-18 T 06-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 BWK49_RS13450 473d6235b969a3099c9703eae5ed65a0 926 Pfam PF00271 Helicase conserved C-terminal domain 354 430 5.2E-5 T 06-07-2017 IPR001650 Helicase, C-terminal BWK49_RS13450 473d6235b969a3099c9703eae5ed65a0 926 Gene3D G3DSA:3.40.50.300 15 198 7.0E-35 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS13450 473d6235b969a3099c9703eae5ed65a0 926 SMART SM00490 345 430 1.0E-13 T 06-07-2017 IPR001650 Helicase, C-terminal BWK49_RS02030 e01362a4dd9dbc04e044fe0933cd051e 41 SUPERFAMILY SSF143011 2 37 2.94E-5 T 06-07-2017 BWK49_RS15795 e0dcdc3312f8992891801c506402dbc0 296 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 181 200 1.0E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15795 e0dcdc3312f8992891801c506402dbc0 296 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 160 1.0E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15795 e0dcdc3312f8992891801c506402dbc0 296 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 99 110 1.0E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15795 e0dcdc3312f8992891801c506402dbc0 296 Gene3D G3DSA:3.40.50.720 3 253 6.2E-60 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS15795 e0dcdc3312f8992891801c506402dbc0 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 200 8.1E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15795 e0dcdc3312f8992891801c506402dbc0 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 146 162 8.1E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15795 e0dcdc3312f8992891801c506402dbc0 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 202 219 8.1E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15795 e0dcdc3312f8992891801c506402dbc0 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 99 110 8.1E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15795 e0dcdc3312f8992891801c506402dbc0 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 8.1E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15795 e0dcdc3312f8992891801c506402dbc0 296 SUPERFAMILY SSF51735 6 256 4.35E-57 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS15795 e0dcdc3312f8992891801c506402dbc0 296 Pfam PF00106 short chain dehydrogenase 9 221 1.7E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS06105 c6bf582e47de5777d2c9c2fd5a1cca51 384 ProSitePatterns PS00737 Thiolases signature 2. 329 345 - T 06-07-2017 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 BWK49_RS06105 c6bf582e47de5777d2c9c2fd5a1cca51 384 Gene3D G3DSA:3.40.47.10 5 124 1.1E-69 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS06105 c6bf582e47de5777d2c9c2fd5a1cca51 384 Gene3D G3DSA:3.40.47.10 186 265 1.1E-69 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS06105 c6bf582e47de5777d2c9c2fd5a1cca51 384 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 381 2.0E-130 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 BWK49_RS06105 c6bf582e47de5777d2c9c2fd5a1cca51 384 Gene3D G3DSA:3.40.47.10 148 185 3.1E-50 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS06105 c6bf582e47de5777d2c9c2fd5a1cca51 384 Gene3D G3DSA:3.40.47.10 267 382 3.1E-50 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS06105 c6bf582e47de5777d2c9c2fd5a1cca51 384 SUPERFAMILY SSF53901 261 382 1.32E-37 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS06105 c6bf582e47de5777d2c9c2fd5a1cca51 384 Pfam PF00108 Thiolase, N-terminal domain 5 252 5.0E-74 T 06-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 BWK49_RS06105 c6bf582e47de5777d2c9c2fd5a1cca51 384 PIRSF PIRSF000429 1 384 3.8E-120 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 BWK49_RS06105 c6bf582e47de5777d2c9c2fd5a1cca51 384 SUPERFAMILY SSF53901 4 260 2.2E-75 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS06105 c6bf582e47de5777d2c9c2fd5a1cca51 384 Pfam PF02803 Thiolase, C-terminal domain 261 381 1.8E-36 T 06-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 BWK49_RS05215 598f703ddd197bb2e8e138ef8f988b5c 307 SUPERFAMILY SSF47240 10 220 3.16E-40 T 06-07-2017 IPR009078 Ferritin-like superfamily BWK49_RS13775 8eea23e475a9e4105c5f9ec785d130b4 280 Gene3D G3DSA:1.10.3720.10 10 267 4.5E-68 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS13775 8eea23e475a9e4105c5f9ec785d130b4 280 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 96 273 6.6E-21 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS13775 8eea23e475a9e4105c5f9ec785d130b4 280 SUPERFAMILY SSF161098 10 277 7.85E-73 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS20105 0b1dad390c71d30766db3048c513c230 367 SMART SM00729 116 340 0.0049 T 06-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 BWK49_RS20105 0b1dad390c71d30766db3048c513c230 367 PIRSF PIRSF006004 11 367 1.4E-114 T 06-07-2017 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 BWK49_RS20105 0b1dad390c71d30766db3048c513c230 367 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 16 367 64.254 T 06-07-2017 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 BWK49_RS20105 0b1dad390c71d30766db3048c513c230 367 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 19 363 1.4E-96 T 06-07-2017 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 BWK49_RS20105 0b1dad390c71d30766db3048c513c230 367 SUPERFAMILY SSF102114 111 337 1.83E-18 T 06-07-2017 BWK49_RS20105 0b1dad390c71d30766db3048c513c230 367 Gene3D G3DSA:3.20.20.70 116 337 3.7E-18 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 BWK49_RS20105 0b1dad390c71d30766db3048c513c230 367 Pfam PF04055 Radical SAM superfamily 121 293 2.3E-23 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 BWK49_RS06885 b8b3ccf7805820c743e46e999af63b67 309 Gene3D G3DSA:2.40.290.10 4 183 1.2E-13 T 06-07-2017 IPR016194 SPOC-like, C-terminal domain BWK49_RS06885 b8b3ccf7805820c743e46e999af63b67 309 Hamap MF_01875 Non-homologous end joining protein Ku [ku]. 1 260 32.641 T 06-07-2017 IPR009187 Non-homologous end joining protein Ku, prokaryotic type BWK49_RS06885 b8b3ccf7805820c743e46e999af63b67 309 SUPERFAMILY SSF100939 1 260 2.35E-58 T 06-07-2017 IPR016194 SPOC-like, C-terminal domain BWK49_RS06885 b8b3ccf7805820c743e46e999af63b67 309 PIRSF PIRSF006493 1 302 2.8E-100 T 06-07-2017 IPR009187 Non-homologous end joining protein Ku, prokaryotic type BWK49_RS06885 b8b3ccf7805820c743e46e999af63b67 309 TIGRFAM TIGR02772 Ku_bact: Ku protein 1 262 1.0E-95 T 06-07-2017 IPR009187 Non-homologous end joining protein Ku, prokaryotic type BWK49_RS06885 b8b3ccf7805820c743e46e999af63b67 309 SMART SM00559 52 184 5.1E-49 T 06-07-2017 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571 BWK49_RS06885 b8b3ccf7805820c743e46e999af63b67 309 Pfam PF02735 Ku70/Ku80 beta-barrel domain 11 192 2.3E-42 T 06-07-2017 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571 BWK49_RS15810 7beb2d2166f54dcdbe21bbe62d2eda6b 368 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 150 1.0E-22 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 BWK49_RS15810 7beb2d2166f54dcdbe21bbe62d2eda6b 368 SMART SM00829 11 362 1.0E-5 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 BWK49_RS15810 7beb2d2166f54dcdbe21bbe62d2eda6b 368 Gene3D G3DSA:3.40.50.720 187 312 4.1E-36 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS15810 7beb2d2166f54dcdbe21bbe62d2eda6b 368 Gene3D G3DSA:3.90.180.10 5 186 2.2E-44 T 06-07-2017 IPR011032 GroES-like BWK49_RS15810 7beb2d2166f54dcdbe21bbe62d2eda6b 368 SUPERFAMILY SSF51735 156 330 6.02E-41 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS15810 7beb2d2166f54dcdbe21bbe62d2eda6b 368 SUPERFAMILY SSF50129 339 360 2.86E-39 T 06-07-2017 IPR011032 GroES-like BWK49_RS15810 7beb2d2166f54dcdbe21bbe62d2eda6b 368 SUPERFAMILY SSF50129 4 161 2.86E-39 T 06-07-2017 IPR011032 GroES-like BWK49_RS15810 7beb2d2166f54dcdbe21bbe62d2eda6b 368 Pfam PF00107 Zinc-binding dehydrogenase 194 328 8.7E-29 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 BWK49_RS21370 93b538592ec6cc48fbf06d846e53c5c1 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 3.1E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS21370 93b538592ec6cc48fbf06d846e53c5c1 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 3.1E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS21370 93b538592ec6cc48fbf06d846e53c5c1 211 SUPERFAMILY SSF48498 90 208 7.87E-29 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS21370 93b538592ec6cc48fbf06d846e53c5c1 211 SUPERFAMILY SSF46689 12 80 7.09E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS21370 93b538592ec6cc48fbf06d846e53c5c1 211 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 68 1.5E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS21370 93b538592ec6cc48fbf06d846e53c5c1 211 Gene3D G3DSA:1.10.10.60 17 70 3.2E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS21370 93b538592ec6cc48fbf06d846e53c5c1 211 Gene3D G3DSA:1.10.357.10 71 208 3.3E-31 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS23475 7172843ac6ceea1855c2a38cd291ca19 450 PRINTS PR00171 Sugar transporter signature 344 365 6.2E-19 T 06-07-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 BWK49_RS23475 7172843ac6ceea1855c2a38cd291ca19 450 PRINTS PR00171 Sugar transporter signature 367 379 6.2E-19 T 06-07-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 BWK49_RS23475 7172843ac6ceea1855c2a38cd291ca19 450 PRINTS PR00171 Sugar transporter signature 102 121 6.2E-19 T 06-07-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 BWK49_RS23475 7172843ac6ceea1855c2a38cd291ca19 450 PRINTS PR00171 Sugar transporter signature 19 29 6.2E-19 T 06-07-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 BWK49_RS23475 7172843ac6ceea1855c2a38cd291ca19 450 PRINTS PR00171 Sugar transporter signature 257 267 6.2E-19 T 06-07-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 BWK49_RS23475 7172843ac6ceea1855c2a38cd291ca19 450 SUPERFAMILY SSF103473 6 440 1.1E-63 T 06-07-2017 IPR020846 Major facilitator superfamily domain BWK49_RS23475 7172843ac6ceea1855c2a38cd291ca19 450 Gene3D G3DSA:1.20.1250.20 246 438 1.0E-15 T 06-07-2017 BWK49_RS23475 7172843ac6ceea1855c2a38cd291ca19 450 Gene3D G3DSA:1.20.1250.20 18 193 7.0E-26 T 06-07-2017 BWK49_RS23475 7172843ac6ceea1855c2a38cd291ca19 450 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 10 439 1.3E-91 T 06-07-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 BWK49_RS23475 7172843ac6ceea1855c2a38cd291ca19 450 ProSitePatterns PS00216 Sugar transport proteins signature 1. 302 319 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 BWK49_RS23475 7172843ac6ceea1855c2a38cd291ca19 450 ProSitePatterns PS00217 Sugar transport proteins signature 2. 107 132 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 BWK49_RS23475 7172843ac6ceea1855c2a38cd291ca19 450 Pfam PF00083 Sugar (and other) transporter 13 443 1.8E-94 T 06-07-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 BWK49_RS04065 56260fc0ce0cc4e0523fdc5881994542 364 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 17 347 6.6E-140 T 06-07-2017 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 BWK49_RS04065 56260fc0ce0cc4e0523fdc5881994542 364 Pfam PF02769 AIR synthase related protein, C-terminal domain 186 350 1.2E-35 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain BWK49_RS04065 56260fc0ce0cc4e0523fdc5881994542 364 SUPERFAMILY SSF55326 17 179 7.67E-45 T 06-07-2017 BWK49_RS04065 56260fc0ce0cc4e0523fdc5881994542 364 Gene3D G3DSA:3.90.650.10 182 350 1.7E-61 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain BWK49_RS04065 56260fc0ce0cc4e0523fdc5881994542 364 Pfam PF00586 AIR synthase related protein, N-terminal domain 70 174 3.6E-16 T 06-07-2017 IPR016188 PurM-like, N-terminal domain BWK49_RS04065 56260fc0ce0cc4e0523fdc5881994542 364 Gene3D G3DSA:3.30.1330.10 33 179 4.2E-51 T 06-07-2017 IPR016188 PurM-like, N-terminal domain BWK49_RS04065 56260fc0ce0cc4e0523fdc5881994542 364 SUPERFAMILY SSF56042 182 350 4.49E-53 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain BWK49_RS04065 56260fc0ce0cc4e0523fdc5881994542 364 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 17 358 40.456 T 06-07-2017 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 BWK49_RS25050 f6a2bb21db549d0d129da0620624caf8 298 Pfam PF00106 short chain dehydrogenase 41 233 6.6E-45 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS25050 f6a2bb21db549d0d129da0620624caf8 298 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 41 185 0.007 T 06-07-2017 BWK49_RS25050 f6a2bb21db549d0d129da0620624caf8 298 Gene3D G3DSA:3.40.50.720 34 256 2.8E-58 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS25050 f6a2bb21db549d0d129da0620624caf8 298 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 171 179 1.1E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS25050 f6a2bb21db549d0d129da0620624caf8 298 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 116 127 1.1E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS25050 f6a2bb21db549d0d129da0620624caf8 298 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 192 211 1.1E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS25050 f6a2bb21db549d0d129da0620624caf8 298 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 192 211 1.9E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS25050 f6a2bb21db549d0d129da0620624caf8 298 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 181 1.9E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS25050 f6a2bb21db549d0d129da0620624caf8 298 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 42 59 1.9E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS25050 f6a2bb21db549d0d129da0620624caf8 298 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 116 127 1.9E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS25050 f6a2bb21db549d0d129da0620624caf8 298 SUPERFAMILY SSF51735 36 283 5.89E-58 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS20325 205b983884e42ae23b9d5bc246bdedb3 610 Gene3D G3DSA:2.30.40.10 503 588 2.7E-11 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 BWK49_RS20325 205b983884e42ae23b9d5bc246bdedb3 610 SUPERFAMILY SSF51556 71 333 5.6E-45 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS20325 205b983884e42ae23b9d5bc246bdedb3 610 SUPERFAMILY SSF51556 382 514 5.6E-45 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS20325 205b983884e42ae23b9d5bc246bdedb3 610 Gene3D G3DSA:3.20.20.140 438 502 1.0E-79 T 06-07-2017 BWK49_RS20325 205b983884e42ae23b9d5bc246bdedb3 610 Gene3D G3DSA:3.20.20.140 85 325 1.0E-79 T 06-07-2017 BWK49_RS20325 205b983884e42ae23b9d5bc246bdedb3 610 Pfam PF07969 Amidohydrolase family 59 214 1.0E-10 T 06-07-2017 IPR013108 Amidohydrolase 3 BWK49_RS20325 205b983884e42ae23b9d5bc246bdedb3 610 Gene3D G3DSA:2.30.40.10 15 84 9.1E-15 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 BWK49_RS20325 205b983884e42ae23b9d5bc246bdedb3 610 SUPERFAMILY SSF51338 15 70 5.7E-16 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 BWK49_RS20325 205b983884e42ae23b9d5bc246bdedb3 610 SUPERFAMILY SSF51338 516 582 5.7E-16 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 BWK49_RS17310 5508b34dca689d59dc9e10a2312b53a8 266 Pfam PF00459 Inositol monophosphatase family 7 258 1.4E-48 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 BWK49_RS17310 5508b34dca689d59dc9e10a2312b53a8 266 Gene3D G3DSA:3.40.190.80 149 259 1.1E-26 T 06-07-2017 BWK49_RS17310 5508b34dca689d59dc9e10a2312b53a8 266 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 211 225 - T 06-07-2017 IPR020550 Inositol monophosphatase, conserved site GO:0046854 BWK49_RS17310 5508b34dca689d59dc9e10a2312b53a8 266 Gene3D G3DSA:3.30.540.10 2 148 2.0E-30 T 06-07-2017 BWK49_RS17310 5508b34dca689d59dc9e10a2312b53a8 266 PRINTS PR00377 Inositol monophosphatase superfamily signature 177 198 1.1E-24 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 BWK49_RS17310 5508b34dca689d59dc9e10a2312b53a8 266 PRINTS PR00377 Inositol monophosphatase superfamily signature 78 94 1.1E-24 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 BWK49_RS17310 5508b34dca689d59dc9e10a2312b53a8 266 PRINTS PR00377 Inositol monophosphatase superfamily signature 37 57 1.1E-24 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 BWK49_RS17310 5508b34dca689d59dc9e10a2312b53a8 266 PRINTS PR00377 Inositol monophosphatase superfamily signature 208 232 1.1E-24 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 BWK49_RS17310 5508b34dca689d59dc9e10a2312b53a8 266 SUPERFAMILY SSF56655 2 258 5.76E-61 T 06-07-2017 BWK49_RS00830 3af0bb6ee49bfd462c780e42dd87e52f 403 SUPERFAMILY SSF56645 3 234 9.69E-58 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS00830 3af0bb6ee49bfd462c780e42dd87e52f 403 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 253 397 1.1E-51 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS00830 3af0bb6ee49bfd462c780e42dd87e52f 403 Gene3D G3DSA:1.10.540.10 3 114 5.9E-26 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS00830 3af0bb6ee49bfd462c780e42dd87e52f 403 SUPERFAMILY SSF47203 253 401 7.09E-56 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS00830 3af0bb6ee49bfd462c780e42dd87e52f 403 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 125 222 4.5E-23 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 BWK49_RS00830 3af0bb6ee49bfd462c780e42dd87e52f 403 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 356 375 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 BWK49_RS00830 3af0bb6ee49bfd462c780e42dd87e52f 403 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 10 114 6.5E-16 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS00830 3af0bb6ee49bfd462c780e42dd87e52f 403 Gene3D G3DSA:1.20.140.10 222 401 7.6E-66 T 06-07-2017 BWK49_RS00830 3af0bb6ee49bfd462c780e42dd87e52f 403 Gene3D G3DSA:2.40.110.10 124 221 1.9E-33 T 06-07-2017 BWK49_RS07340 084ddfd5c89aeb84cd1f325549d517aa 650 SUPERFAMILY SSF53448 182 253 1.69E-16 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases BWK49_RS07340 084ddfd5c89aeb84cd1f325549d517aa 650 SUPERFAMILY SSF53448 26 149 1.69E-16 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases BWK49_RS07340 084ddfd5c89aeb84cd1f325549d517aa 650 Gene3D G3DSA:3.90.550.10 27 255 3.2E-11 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases BWK49_RS07340 084ddfd5c89aeb84cd1f325549d517aa 650 SUPERFAMILY SSF53756 314 646 1.03E-56 T 06-07-2017 BWK49_RS07340 084ddfd5c89aeb84cd1f325549d517aa 650 Gene3D G3DSA:3.40.50.2000 479 627 2.5E-21 T 06-07-2017 BWK49_RS07340 084ddfd5c89aeb84cd1f325549d517aa 650 Pfam PF00534 Glycosyl transferases group 1 479 627 2.1E-24 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 BWK49_RS20055 6bac39a69cfc68f87cf5d617c6248f22 285 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 42 283 1.7E-91 T 06-07-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 BWK49_RS20055 6bac39a69cfc68f87cf5d617c6248f22 285 Pfam PF00557 Metallopeptidase family M24 48 276 5.3E-53 T 06-07-2017 IPR000994 Peptidase M24, structural domain BWK49_RS20055 6bac39a69cfc68f87cf5d617c6248f22 285 Gene3D G3DSA:3.90.230.10 41 284 7.0E-97 T 06-07-2017 IPR000994 Peptidase M24, structural domain BWK49_RS20055 6bac39a69cfc68f87cf5d617c6248f22 285 SUPERFAMILY SSF55920 9 284 7.2E-90 T 06-07-2017 IPR000994 Peptidase M24, structural domain BWK49_RS20055 6bac39a69cfc68f87cf5d617c6248f22 285 PRINTS PR00599 Methionine aminopeptidase-1 signature 126 142 6.3E-23 T 06-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase BWK49_RS20055 6bac39a69cfc68f87cf5d617c6248f22 285 PRINTS PR00599 Methionine aminopeptidase-1 signature 104 117 6.3E-23 T 06-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase BWK49_RS20055 6bac39a69cfc68f87cf5d617c6248f22 285 PRINTS PR00599 Methionine aminopeptidase-1 signature 196 208 6.3E-23 T 06-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase BWK49_RS20055 6bac39a69cfc68f87cf5d617c6248f22 285 PRINTS PR00599 Methionine aminopeptidase-1 signature 227 239 6.3E-23 T 06-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase BWK49_RS20055 6bac39a69cfc68f87cf5d617c6248f22 285 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 202 220 - T 06-07-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 BWK49_RS20055 6bac39a69cfc68f87cf5d617c6248f22 285 Hamap MF_01974 Methionine aminopeptidase [map]. 39 285 40.705 T 06-07-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 BWK49_RS21425 fec091c4202390857f4738c76cf3e92a 508 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 177 190 - T 06-07-2017 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 BWK49_RS21425 fec091c4202390857f4738c76cf3e92a 508 SUPERFAMILY SSF53067 170 353 1.99E-29 T 06-07-2017 BWK49_RS21425 fec091c4202390857f4738c76cf3e92a 508 Gene3D G3DSA:3.30.420.40 2 62 2.1E-30 T 06-07-2017 BWK49_RS21425 fec091c4202390857f4738c76cf3e92a 508 Gene3D G3DSA:3.30.420.40 95 182 2.1E-30 T 06-07-2017 BWK49_RS21425 fec091c4202390857f4738c76cf3e92a 508 SUPERFAMILY SSF53067 2 163 1.62E-27 T 06-07-2017 BWK49_RS21425 fec091c4202390857f4738c76cf3e92a 508 Gene3D G3DSA:3.30.420.40 183 337 6.0E-19 T 06-07-2017 BWK49_RS21425 fec091c4202390857f4738c76cf3e92a 508 Pfam PF00012 Hsp70 protein 76 354 1.5E-30 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 BWK49_RS21425 fec091c4202390857f4738c76cf3e92a 508 PRINTS PR00301 70kDa heat shock protein signature 119 139 2.3E-12 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 BWK49_RS21425 fec091c4202390857f4738c76cf3e92a 508 PRINTS PR00301 70kDa heat shock protein signature 183 193 2.3E-12 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 BWK49_RS21425 fec091c4202390857f4738c76cf3e92a 508 PRINTS PR00301 70kDa heat shock protein signature 1 14 2.3E-12 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 BWK49_RS21425 fec091c4202390857f4738c76cf3e92a 508 PRINTS PR00301 70kDa heat shock protein signature 28 40 2.3E-12 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 BWK49_RS21425 fec091c4202390857f4738c76cf3e92a 508 PRINTS PR00301 70kDa heat shock protein signature 309 325 2.3E-12 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 BWK49_RS24700 0fb0c40f8d79b02974cf926b325c6aa1 573 TIGRFAM TIGR01447 recD: exodeoxyribonuclease V, alpha subunit 14 566 3.6E-155 T 06-07-2017 IPR006344 RecBCD enzyme subunit RecD GO:0004386|GO:0006302|GO:0006310|GO:0008854|GO:0009338 BWK49_RS24700 0fb0c40f8d79b02974cf926b325c6aa1 573 Pfam PF13538 UvrD-like helicase C-terminal domain 496 542 1.9E-14 T 06-07-2017 IPR027785 UvrD-like helicase C-terminal domain BWK49_RS24700 0fb0c40f8d79b02974cf926b325c6aa1 573 Gene3D G3DSA:3.40.50.300 142 345 1.5E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS24700 0fb0c40f8d79b02974cf926b325c6aa1 573 Pfam PF13604 AAA domain 146 363 3.1E-37 T 06-07-2017 BWK49_RS24700 0fb0c40f8d79b02974cf926b325c6aa1 573 SUPERFAMILY SSF52540 146 547 8.22E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS24700 0fb0c40f8d79b02974cf926b325c6aa1 573 Gene3D G3DSA:3.40.50.300 492 546 6.4E-9 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS24700 0fb0c40f8d79b02974cf926b325c6aa1 573 Hamap MF_01487 RecBCD enzyme subunit RecD [recD]. 21 564 43.522 T 06-07-2017 IPR006344 RecBCD enzyme subunit RecD GO:0004386|GO:0006302|GO:0006310|GO:0008854|GO:0009338 BWK49_RS24700 0fb0c40f8d79b02974cf926b325c6aa1 573 SMART SM00382 157 321 7.0E-4 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS21070 353e59e895c64d6b6b31212ddcd8ffa3 278 SMART SM00563 92 204 6.3E-28 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 BWK49_RS21070 353e59e895c64d6b6b31212ddcd8ffa3 278 Gene3D G3DSA:3.40.1130.10 86 188 3.2E-7 T 06-07-2017 BWK49_RS21070 353e59e895c64d6b6b31212ddcd8ffa3 278 Pfam PF01553 Acyltransferase 79 200 8.1E-21 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 BWK49_RS21070 353e59e895c64d6b6b31212ddcd8ffa3 278 SUPERFAMILY SSF69593 38 213 3.27E-22 T 06-07-2017 BWK49_RS13105 77203b7e83aacc71266b0be3bc1d3951 385 ProSitePatterns PS01134 FtsZ protein signature 1. 41 75 - T 06-07-2017 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 BWK49_RS13105 77203b7e83aacc71266b0be3bc1d3951 385 PRINTS PR00423 Cell division protein FtsZ signature 186 208 1.7E-50 T 06-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 BWK49_RS13105 77203b7e83aacc71266b0be3bc1d3951 385 PRINTS PR00423 Cell division protein FtsZ signature 95 115 1.7E-50 T 06-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 BWK49_RS13105 77203b7e83aacc71266b0be3bc1d3951 385 PRINTS PR00423 Cell division protein FtsZ signature 123 144 1.7E-50 T 06-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 BWK49_RS13105 77203b7e83aacc71266b0be3bc1d3951 385 PRINTS PR00423 Cell division protein FtsZ signature 209 230 1.7E-50 T 06-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 BWK49_RS13105 77203b7e83aacc71266b0be3bc1d3951 385 Pfam PF12327 FtsZ family, C-terminal domain 219 313 2.2E-34 T 06-07-2017 IPR024757 Cell division protein FtsZ, C-terminal BWK49_RS13105 77203b7e83aacc71266b0be3bc1d3951 385 ProSitePatterns PS01135 FtsZ protein signature 2. 94 115 - T 06-07-2017 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 BWK49_RS13105 77203b7e83aacc71266b0be3bc1d3951 385 SMART SM00864 10 202 1.1E-106 T 06-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 BWK49_RS13105 77203b7e83aacc71266b0be3bc1d3951 385 Gene3D G3DSA:3.30.1330.20 212 314 7.0E-47 T 06-07-2017 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-983189 BWK49_RS13105 77203b7e83aacc71266b0be3bc1d3951 385 SUPERFAMILY SSF52490 9 205 4.19E-66 T 06-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 BWK49_RS13105 77203b7e83aacc71266b0be3bc1d3951 385 SUPERFAMILY SSF55307 201 314 1.69E-42 T 06-07-2017 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 BWK49_RS13105 77203b7e83aacc71266b0be3bc1d3951 385 Gene3D G3DSA:3.40.50.1440 11 211 5.8E-90 T 06-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 BWK49_RS13105 77203b7e83aacc71266b0be3bc1d3951 385 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 8 314 7.5E-125 T 06-07-2017 IPR000158 Cell division protein FtsZ GO:0005525 BWK49_RS13105 77203b7e83aacc71266b0be3bc1d3951 385 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 11 169 3.9E-39 T 06-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 BWK49_RS13105 77203b7e83aacc71266b0be3bc1d3951 385 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 6 334 38.046 T 06-07-2017 IPR000158 Cell division protein FtsZ GO:0005525 BWK49_RS13105 77203b7e83aacc71266b0be3bc1d3951 385 SMART SM00865 204 321 1.4E-53 T 06-07-2017 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-983189 BWK49_RS15540 f8658128decb94308b6a9a72e414ecf9 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 3.9E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15540 f8658128decb94308b6a9a72e414ecf9 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 3.9E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15540 f8658128decb94308b6a9a72e414ecf9 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 3.9E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15540 f8658128decb94308b6a9a72e414ecf9 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 3.9E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15540 f8658128decb94308b6a9a72e414ecf9 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 3.9E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15540 f8658128decb94308b6a9a72e414ecf9 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 3.9E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15540 f8658128decb94308b6a9a72e414ecf9 253 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 198 8.5E-4 T 06-07-2017 BWK49_RS15540 f8658128decb94308b6a9a72e414ecf9 253 Pfam PF00106 short chain dehydrogenase 8 203 4.3E-54 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15540 f8658128decb94308b6a9a72e414ecf9 253 Gene3D G3DSA:3.40.50.720 3 241 1.2E-68 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS15540 f8658128decb94308b6a9a72e414ecf9 253 PIRSF PIRSF000126 1 253 8.0E-51 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15540 f8658128decb94308b6a9a72e414ecf9 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 161 180 6.9E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15540 f8658128decb94308b6a9a72e414ecf9 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 6.9E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15540 f8658128decb94308b6a9a72e414ecf9 253 SUPERFAMILY SSF51735 3 237 3.2E-66 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS02940 6d480e3e188a57d32cfb40cd91539345 553 Gene3D G3DSA:3.30.70.1230 356 502 2.8E-29 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 BWK49_RS02940 6d480e3e188a57d32cfb40cd91539345 553 SMART SM00044 325 522 7.3E-6 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 BWK49_RS02940 6d480e3e188a57d32cfb40cd91539345 553 Pfam PF00672 HAMP domain 258 325 1.0E-10 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 BWK49_RS02940 6d480e3e188a57d32cfb40cd91539345 553 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 358 525 4.0E-19 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 BWK49_RS02940 6d480e3e188a57d32cfb40cd91539345 553 SUPERFAMILY SSF55073 353 532 5.34E-43 T 06-07-2017 IPR029787 Nucleotide cyclase BWK49_RS02940 6d480e3e188a57d32cfb40cd91539345 553 SUPERFAMILY SSF158472 278 326 1.57E-6 T 06-07-2017 BWK49_RS02940 6d480e3e188a57d32cfb40cd91539345 553 SMART SM00304 277 329 3.0E-9 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 BWK49_RS15055 9bdea776e05255f46f01aeb5da98bc66 296 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 46 261 1.4E-35 T 06-07-2017 IPR018713 Domain of unknown function DUF2236 BWK49_RS20565 174dbe037575831bba16b0d7850841dc 747 SUPERFAMILY SSF81653 220 312 6.41E-22 T 06-07-2017 BWK49_RS20565 174dbe037575831bba16b0d7850841dc 747 Gene3D G3DSA:3.40.1110.10 424 532 1.3E-20 T 06-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 BWK49_RS20565 174dbe037575831bba16b0d7850841dc 747 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 185 688 8.2E-75 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 BWK49_RS20565 174dbe037575831bba16b0d7850841dc 747 ProSitePatterns PS01229 Hypothetical cof family signature 2. 607 629 - T 06-07-2017 BWK49_RS20565 174dbe037575831bba16b0d7850841dc 747 Gene3D G3DSA:2.70.150.10 214 313 5.3E-21 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 BWK49_RS20565 174dbe037575831bba16b0d7850841dc 747 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 144 710 1.3E-126 T 06-07-2017 BWK49_RS20565 174dbe037575831bba16b0d7850841dc 747 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 631 643 2.1E-26 T 06-07-2017 BWK49_RS20565 174dbe037575831bba16b0d7850841dc 747 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 531 542 2.1E-26 T 06-07-2017 BWK49_RS20565 174dbe037575831bba16b0d7850841dc 747 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 263 277 2.1E-26 T 06-07-2017 BWK49_RS20565 174dbe037575831bba16b0d7850841dc 747 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 554 564 2.1E-26 T 06-07-2017 BWK49_RS20565 174dbe037575831bba16b0d7850841dc 747 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 607 626 2.1E-26 T 06-07-2017 BWK49_RS20565 174dbe037575831bba16b0d7850841dc 747 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 405 419 2.1E-26 T 06-07-2017 BWK49_RS20565 174dbe037575831bba16b0d7850841dc 747 Gene3D G3DSA:3.40.50.1000 533 653 1.2E-42 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS20565 174dbe037575831bba16b0d7850841dc 747 Gene3D G3DSA:3.40.1110.10 396 423 2.9E-4 T 06-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 BWK49_RS20565 174dbe037575831bba16b0d7850841dc 747 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 163 710 3.4E-173 T 06-07-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 BWK49_RS20565 174dbe037575831bba16b0d7850841dc 747 SUPERFAMILY SSF81665 314 425 2.48E-5 T 06-07-2017 BWK49_RS20565 174dbe037575831bba16b0d7850841dc 747 SUPERFAMILY SSF81665 168 216 2.48E-5 T 06-07-2017 BWK49_RS20565 174dbe037575831bba16b0d7850841dc 747 Pfam PF00702 haloacid dehalogenase-like hydrolase 401 621 4.3E-44 T 06-07-2017 BWK49_RS20565 174dbe037575831bba16b0d7850841dc 747 SUPERFAMILY SSF56784 463 707 2.69E-55 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS20565 174dbe037575831bba16b0d7850841dc 747 SUPERFAMILY SSF56784 404 423 2.69E-55 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS20565 174dbe037575831bba16b0d7850841dc 747 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 407 413 - T 06-07-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 BWK49_RS20565 174dbe037575831bba16b0d7850841dc 747 Pfam PF00122 E1-E2 ATPase 185 396 2.0E-53 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 BWK49_RS10040 b7072e1c215c73873996026adca84991 729 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 550 723 2.4E-32 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 BWK49_RS10040 b7072e1c215c73873996026adca84991 729 SUPERFAMILY SSF55073 543 723 5.81E-41 T 06-07-2017 IPR029787 Nucleotide cyclase BWK49_RS10040 b7072e1c215c73873996026adca84991 729 Pfam PF00672 HAMP domain 446 512 1.9E-16 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 BWK49_RS10040 b7072e1c215c73873996026adca84991 729 SUPERFAMILY SSF158472 468 512 2.35E-10 T 06-07-2017 BWK49_RS10040 b7072e1c215c73873996026adca84991 729 Gene3D G3DSA:3.30.70.1230 544 726 4.0E-41 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 BWK49_RS10040 b7072e1c215c73873996026adca84991 729 SMART SM00304 465 517 1.1E-13 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 BWK49_RS10040 b7072e1c215c73873996026adca84991 729 SMART SM00044 521 712 7.5E-23 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 BWK49_RS12160 a364667973b5e75b4ac7059bef2ba452 282 ProSitePatterns PS00380 Rhodanese signature 1. 42 53 - T 06-07-2017 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 BWK49_RS12160 a364667973b5e75b4ac7059bef2ba452 282 ProSitePatterns PS00683 Rhodanese C-terminal signature. 261 271 - T 06-07-2017 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 BWK49_RS12160 a364667973b5e75b4ac7059bef2ba452 282 SUPERFAMILY SSF52821 166 282 1.22E-29 T 06-07-2017 IPR001763 Rhodanese-like domain BWK49_RS12160 a364667973b5e75b4ac7059bef2ba452 282 SUPERFAMILY SSF52821 4 152 2.75E-37 T 06-07-2017 IPR001763 Rhodanese-like domain BWK49_RS12160 a364667973b5e75b4ac7059bef2ba452 282 Gene3D G3DSA:3.40.250.10 6 151 1.4E-40 T 06-07-2017 IPR001763 Rhodanese-like domain BWK49_RS12160 a364667973b5e75b4ac7059bef2ba452 282 Gene3D G3DSA:3.40.250.10 165 280 9.8E-33 T 06-07-2017 IPR001763 Rhodanese-like domain BWK49_RS12160 a364667973b5e75b4ac7059bef2ba452 282 SMART SM00450 159 277 5.8E-18 T 06-07-2017 IPR001763 Rhodanese-like domain BWK49_RS12160 a364667973b5e75b4ac7059bef2ba452 282 SMART SM00450 10 135 2.3E-24 T 06-07-2017 IPR001763 Rhodanese-like domain BWK49_RS12160 a364667973b5e75b4ac7059bef2ba452 282 Pfam PF00581 Rhodanese-like domain 11 131 3.1E-17 T 06-07-2017 IPR001763 Rhodanese-like domain BWK49_RS12160 a364667973b5e75b4ac7059bef2ba452 282 Pfam PF00581 Rhodanese-like domain 166 273 6.5E-11 T 06-07-2017 IPR001763 Rhodanese-like domain BWK49_RS21560 79da898d1ecb20679df9673e67443898 417 SUPERFAMILY SSF51338 375 414 1.77E-13 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 BWK49_RS21560 79da898d1ecb20679df9673e67443898 417 SUPERFAMILY SSF51338 3 59 1.77E-13 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 BWK49_RS21560 79da898d1ecb20679df9673e67443898 417 Gene3D G3DSA:2.30.40.10 3 60 6.6E-24 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 BWK49_RS21560 79da898d1ecb20679df9673e67443898 417 Gene3D G3DSA:2.30.40.10 384 414 6.6E-24 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 BWK49_RS21560 79da898d1ecb20679df9673e67443898 417 Gene3D G3DSA:2.30.40.10 358 383 6.5E-6 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 BWK49_RS21560 79da898d1ecb20679df9673e67443898 417 Gene3D G3DSA:3.20.20.140 85 357 1.0E-86 T 06-07-2017 BWK49_RS21560 79da898d1ecb20679df9673e67443898 417 SUPERFAMILY SSF51556 59 375 3.22E-89 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS21560 79da898d1ecb20679df9673e67443898 417 Pfam PF01979 Amidohydrolase family 56 411 1.4E-36 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 BWK49_RS03870 966fac8c09bf3c17567a8c0449903035 472 Pfam PF10397 Adenylosuccinate lyase C-terminus 366 449 1.3E-13 T 06-07-2017 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 BWK49_RS03870 966fac8c09bf3c17567a8c0449903035 472 SMART SM00998 365 450 8.0E-22 T 06-07-2017 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 BWK49_RS03870 966fac8c09bf3c17567a8c0449903035 472 SUPERFAMILY SSF48557 6 450 4.56E-80 T 06-07-2017 IPR008948 L-Aspartase-like GO:0003824 BWK49_RS03870 966fac8c09bf3c17567a8c0449903035 472 Pfam PF00206 Lyase 32 296 3.7E-22 T 06-07-2017 IPR022761 Fumarate lyase, N-terminal BWK49_RS03870 966fac8c09bf3c17567a8c0449903035 472 PRINTS PR00149 Fumarate lyase superfamily signature 94 112 7.3E-10 T 06-07-2017 IPR000362 Fumarate lyase family BWK49_RS03870 966fac8c09bf3c17567a8c0449903035 472 PRINTS PR00149 Fumarate lyase superfamily signature 139 157 7.3E-10 T 06-07-2017 IPR000362 Fumarate lyase family BWK49_RS03870 966fac8c09bf3c17567a8c0449903035 472 PRINTS PR00149 Fumarate lyase superfamily signature 276 292 7.3E-10 T 06-07-2017 IPR000362 Fumarate lyase family BWK49_RS03870 966fac8c09bf3c17567a8c0449903035 472 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 7 449 2.2E-139 T 06-07-2017 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 BWK49_RS03870 966fac8c09bf3c17567a8c0449903035 472 ProSitePatterns PS00163 Fumarate lyases signature. 276 285 - T 06-07-2017 IPR020557 Fumarate lyase, conserved site GO:0003824 BWK49_RS03870 966fac8c09bf3c17567a8c0449903035 472 Gene3D G3DSA:1.20.200.10 98 447 1.6E-80 T 06-07-2017 BWK49_RS03870 966fac8c09bf3c17567a8c0449903035 472 Gene3D G3DSA:1.10.275.10 9 97 2.2E-23 T 06-07-2017 IPR024083 Fumarase/histidase, N-terminal BWK49_RS24980 c88d242e0e29c761c0945233fac48669 578 Pfam PF07969 Amidohydrolase family 43 560 1.2E-48 T 06-07-2017 IPR013108 Amidohydrolase 3 BWK49_RS24980 c88d242e0e29c761c0945233fac48669 578 Gene3D G3DSA:2.30.40.10 2 68 3.4E-19 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 BWK49_RS24980 c88d242e0e29c761c0945233fac48669 578 Gene3D G3DSA:2.30.40.10 491 575 1.5E-10 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 BWK49_RS24980 c88d242e0e29c761c0945233fac48669 578 Gene3D G3DSA:3.20.20.140 428 490 1.4E-79 T 06-07-2017 BWK49_RS24980 c88d242e0e29c761c0945233fac48669 578 Gene3D G3DSA:3.20.20.140 69 307 1.4E-79 T 06-07-2017 BWK49_RS24980 c88d242e0e29c761c0945233fac48669 578 SUPERFAMILY SSF51556 55 315 2.65E-59 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS24980 c88d242e0e29c761c0945233fac48669 578 SUPERFAMILY SSF51556 374 506 2.65E-59 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS24980 c88d242e0e29c761c0945233fac48669 578 SUPERFAMILY SSF51338 1 54 3.09E-21 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 BWK49_RS24980 c88d242e0e29c761c0945233fac48669 578 SUPERFAMILY SSF51338 506 574 3.09E-21 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 BWK49_RS11615 252be88fcc484779047f952db62e0451 654 SUPERFAMILY SSF52540 420 644 1.33E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS11615 252be88fcc484779047f952db62e0451 654 Pfam PF00005 ABC transporter 226 359 1.5E-18 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 BWK49_RS11615 252be88fcc484779047f952db62e0451 654 Pfam PF00005 ABC transporter 455 592 8.2E-23 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 BWK49_RS11615 252be88fcc484779047f952db62e0451 654 ProSitePatterns PS00211 ABC transporters family signature. 332 346 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 BWK49_RS11615 252be88fcc484779047f952db62e0451 654 Gene3D G3DSA:3.40.50.300 433 646 4.4E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS11615 252be88fcc484779047f952db62e0451 654 SMART SM00382 464 642 9.7E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS11615 252be88fcc484779047f952db62e0451 654 SMART SM00382 235 408 1.3E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS11615 252be88fcc484779047f952db62e0451 654 Gene3D G3DSA:3.40.50.300 210 406 1.7E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS11615 252be88fcc484779047f952db62e0451 654 SUPERFAMILY SSF52540 204 406 2.5E-39 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS11615 252be88fcc484779047f952db62e0451 654 ProSitePatterns PS00211 ABC transporters family signature. 565 579 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 BWK49_RS22460 15a1c3159817061e0bf7588cd39d425c 218 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 1 184 37.43 T 06-07-2017 IPR004507 Flavin prenyltransferase UbiX/Pad1 BWK49_RS22460 15a1c3159817061e0bf7588cd39d425c 218 SUPERFAMILY SSF52507 1 184 6.15E-61 T 06-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 BWK49_RS22460 15a1c3159817061e0bf7588cd39d425c 218 Pfam PF02441 Flavoprotein 1 127 3.4E-27 T 06-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 BWK49_RS22460 15a1c3159817061e0bf7588cd39d425c 218 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 2 182 8.7E-81 T 06-07-2017 IPR004507 Flavin prenyltransferase UbiX/Pad1 BWK49_RS22460 15a1c3159817061e0bf7588cd39d425c 218 Gene3D G3DSA:3.40.50.1950 1 187 2.0E-79 T 06-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 BWK49_RS16920 dac9a466a8f7304b583cc920ebbc959f 1033 SMART SM01294 882 949 6.5E-6 T 06-07-2017 BWK49_RS16920 dac9a466a8f7304b583cc920ebbc959f 1033 SUPERFAMILY SSF55048 626 687 1.44E-11 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 BWK49_RS16920 dac9a466a8f7304b583cc920ebbc959f 1033 SUPERFAMILY SSF47336 874 956 6.94E-22 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS16920 dac9a466a8f7304b583cc920ebbc959f 1033 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 232 347 3.1E-38 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal BWK49_RS16920 dac9a466a8f7304b583cc920ebbc959f 1033 Gene3D G3DSA:1.10.1200.10 878 953 2.1E-23 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS16920 dac9a466a8f7304b583cc920ebbc959f 1033 SMART SM00825 Beta-ketoacyl synthase 6 401 7.6E-164 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain BWK49_RS16920 dac9a466a8f7304b583cc920ebbc959f 1033 SMART SM00823 Phosphopantetheine attachment site 881 953 2.7E-31 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS16920 dac9a466a8f7304b583cc920ebbc959f 1033 ProSitePatterns PS00012 Phosphopantetheine attachment site. 908 923 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site BWK49_RS16920 dac9a466a8f7304b583cc920ebbc959f 1033 Gene3D G3DSA:3.40.366.10 687 798 9.6E-81 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 BWK49_RS16920 dac9a466a8f7304b583cc920ebbc959f 1033 Gene3D G3DSA:3.40.366.10 497 621 9.6E-81 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 BWK49_RS16920 dac9a466a8f7304b583cc920ebbc959f 1033 Pfam PF00698 Acyl transferase domain 501 811 2.3E-68 T 06-07-2017 IPR014043 Acyl transferase BWK49_RS16920 dac9a466a8f7304b583cc920ebbc959f 1033 SUPERFAMILY SSF53901 376 397 4.83E-75 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS16920 dac9a466a8f7304b583cc920ebbc959f 1033 SUPERFAMILY SSF53901 4 344 4.83E-75 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS16920 dac9a466a8f7304b583cc920ebbc959f 1033 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 351 466 1.2E-20 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS16920 dac9a466a8f7304b583cc920ebbc959f 1033 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 503 794 4.1E-111 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain BWK49_RS16920 dac9a466a8f7304b583cc920ebbc959f 1033 Gene3D G3DSA:3.40.47.10 6 236 1.7E-73 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS16920 dac9a466a8f7304b583cc920ebbc959f 1033 SUPERFAMILY SSF52151 688 790 3.66E-75 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 BWK49_RS16920 dac9a466a8f7304b583cc920ebbc959f 1033 SUPERFAMILY SSF52151 499 627 3.66E-75 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 BWK49_RS16920 dac9a466a8f7304b583cc920ebbc959f 1033 Gene3D G3DSA:3.30.70.250 626 686 4.6E-8 T 06-07-2017 BWK49_RS16920 dac9a466a8f7304b583cc920ebbc959f 1033 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 5 36 1.3E-5 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal BWK49_RS16920 dac9a466a8f7304b583cc920ebbc959f 1033 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 37 222 3.3E-55 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal BWK49_RS16920 dac9a466a8f7304b583cc920ebbc959f 1033 Gene3D G3DSA:3.40.47.10 237 400 9.2E-58 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS16920 dac9a466a8f7304b583cc920ebbc959f 1033 Pfam PF00550 Phosphopantetheine attachment site 884 949 2.1E-11 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS11440 cc3d131af94cff8a4bfc2be943aa4c3b 709 SMART SM00322 19 82 4.1E-8 T 06-07-2017 IPR004087 K Homology domain GO:0003676 BWK49_RS11440 cc3d131af94cff8a4bfc2be943aa4c3b 709 SUPERFAMILY SSF52540 122 241 1.49E-19 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS11440 cc3d131af94cff8a4bfc2be943aa4c3b 709 Pfam PF02562 PhoH-like protein 597 685 2.8E-34 T 06-07-2017 IPR003714 PhoH-like protein GO:0005524 BWK49_RS11440 cc3d131af94cff8a4bfc2be943aa4c3b 709 Pfam PF02562 PhoH-like protein 126 241 1.3E-49 T 06-07-2017 IPR003714 PhoH-like protein GO:0005524 BWK49_RS11440 cc3d131af94cff8a4bfc2be943aa4c3b 709 SUPERFAMILY SSF51294 246 370 1.44E-13 T 06-07-2017 IPR028992 Hedgehog/Intein (Hint) domain BWK49_RS11440 cc3d131af94cff8a4bfc2be943aa4c3b 709 SUPERFAMILY SSF51294 531 597 1.44E-13 T 06-07-2017 IPR028992 Hedgehog/Intein (Hint) domain BWK49_RS11440 cc3d131af94cff8a4bfc2be943aa4c3b 709 SUPERFAMILY SSF54791 19 81 3.34E-6 T 06-07-2017 IPR004088 K Homology domain, type 1 GO:0003723 BWK49_RS11440 cc3d131af94cff8a4bfc2be943aa4c3b 709 SUPERFAMILY SSF52540 591 658 6.44E-13 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS11440 cc3d131af94cff8a4bfc2be943aa4c3b 709 Gene3D G3DSA:3.10.28.10 444 548 1.2E-20 T 06-07-2017 IPR027434 Homing endonuclease GO:0004519 BWK49_RS11440 cc3d131af94cff8a4bfc2be943aa4c3b 709 Gene3D G3DSA:2.170.16.10 247 373 1.4E-10 T 06-07-2017 IPR028992 Hedgehog/Intein (Hint) domain BWK49_RS11440 cc3d131af94cff8a4bfc2be943aa4c3b 709 Gene3D G3DSA:3.40.50.300 604 686 2.0E-92 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS11440 cc3d131af94cff8a4bfc2be943aa4c3b 709 Gene3D G3DSA:3.40.50.300 124 246 2.0E-92 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS11440 cc3d131af94cff8a4bfc2be943aa4c3b 709 Pfam PF00013 KH domain 24 79 8.5E-5 T 06-07-2017 IPR004088 K Homology domain, type 1 GO:0003723 BWK49_RS11440 cc3d131af94cff8a4bfc2be943aa4c3b 709 Gene3D G3DSA:3.30.1370.10 20 81 7.5E-4 T 06-07-2017 IPR004088 K Homology domain, type 1 GO:0003723 BWK49_RS11440 cc3d131af94cff8a4bfc2be943aa4c3b 709 SUPERFAMILY SSF55608 440 544 6.8E-13 T 06-07-2017 IPR027434 Homing endonuclease GO:0004519 BWK49_RS10450 0ca4f7795ad7df5cda4b1651e46cc860 1150 Gene3D G3DSA:3.40.50.980 703 851 2.2E-38 T 06-07-2017 BWK49_RS10450 0ca4f7795ad7df5cda4b1651e46cc860 1150 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1073 1088 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site BWK49_RS10450 0ca4f7795ad7df5cda4b1651e46cc860 1150 Gene3D G3DSA:3.30.300.30 942 1053 2.5E-29 T 06-07-2017 BWK49_RS10450 0ca4f7795ad7df5cda4b1651e46cc860 1150 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 577 971 2.1E-116 T 06-07-2017 IPR010071 Amino acid adenylation domain BWK49_RS10450 0ca4f7795ad7df5cda4b1651e46cc860 1150 Gene3D G3DSA:3.40.50.980 546 702 5.5E-34 T 06-07-2017 BWK49_RS10450 0ca4f7795ad7df5cda4b1651e46cc860 1150 SUPERFAMILY SSF52777 94 285 4.52E-24 T 06-07-2017 BWK49_RS10450 0ca4f7795ad7df5cda4b1651e46cc860 1150 SMART SM00823 Phosphopantetheine attachment site 1049 1119 1.9E-4 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS10450 0ca4f7795ad7df5cda4b1651e46cc860 1150 Pfam PF00501 AMP-binding enzyme 552 947 1.6E-85 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS10450 0ca4f7795ad7df5cda4b1651e46cc860 1150 SUPERFAMILY SSF47336 6 109 1.06E-10 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS10450 0ca4f7795ad7df5cda4b1651e46cc860 1150 SUPERFAMILY SSF52777 273 515 1.56E-39 T 06-07-2017 BWK49_RS10450 0ca4f7795ad7df5cda4b1651e46cc860 1150 Pfam PF00550 Phosphopantetheine attachment site 1051 1115 1.3E-11 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS10450 0ca4f7795ad7df5cda4b1651e46cc860 1150 Pfam PF00550 Phosphopantetheine attachment site 7 67 8.8E-7 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS10450 0ca4f7795ad7df5cda4b1651e46cc860 1150 Pfam PF13193 AMP-binding enzyme C-terminal domain 955 1022 1.2E-8 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS10450 0ca4f7795ad7df5cda4b1651e46cc860 1150 Pfam PF08415 Nonribosomal peptide synthase 410 466 1.7E-15 T 06-07-2017 IPR013624 Non-ribosomal peptide synthetase BWK49_RS10450 0ca4f7795ad7df5cda4b1651e46cc860 1150 SUPERFAMILY SSF56801 542 1062 4.32E-133 T 06-07-2017 BWK49_RS10450 0ca4f7795ad7df5cda4b1651e46cc860 1150 SUPERFAMILY SSF47336 1043 1116 2.22E-15 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS10450 0ca4f7795ad7df5cda4b1651e46cc860 1150 ProSitePatterns PS00455 Putative AMP-binding domain signature. 692 703 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS10450 0ca4f7795ad7df5cda4b1651e46cc860 1150 Pfam PF00668 Condensation domain 97 387 4.0E-38 T 06-07-2017 IPR001242 Condensation domain BWK49_RS10450 0ca4f7795ad7df5cda4b1651e46cc860 1150 Gene3D G3DSA:2.30.38.10 861 937 3.6E-25 T 06-07-2017 BWK49_RS10450 0ca4f7795ad7df5cda4b1651e46cc860 1150 Gene3D G3DSA:1.10.1200.10 8 73 2.4E-6 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS10450 0ca4f7795ad7df5cda4b1651e46cc860 1150 Gene3D G3DSA:1.10.1200.10 1054 1119 5.9E-22 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS16945 57f8c52b0f58401899942a0b92c733d5 405 Hamap MF_00005 Argininosuccinate synthase [argG]. 2 397 51.451 T 06-07-2017 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 BWK49_RS16945 57f8c52b0f58401899942a0b92c733d5 405 Gene3D G3DSA:3.40.50.620 3 173 3.5E-53 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold BWK49_RS16945 57f8c52b0f58401899942a0b92c733d5 405 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 117 128 - T 06-07-2017 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 BWK49_RS16945 57f8c52b0f58401899942a0b92c733d5 405 Pfam PF00764 Arginosuccinate synthase 6 392 6.3E-186 T 06-07-2017 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 BWK49_RS16945 57f8c52b0f58401899942a0b92c733d5 405 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 8 16 - T 06-07-2017 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 BWK49_RS16945 57f8c52b0f58401899942a0b92c733d5 405 Gene3D G3DSA:3.90.1260.10 174 397 9.1E-81 T 06-07-2017 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 BWK49_RS16945 57f8c52b0f58401899942a0b92c733d5 405 TIGRFAM TIGR00032 argG: argininosuccinate synthase 4 394 4.8E-144 T 06-07-2017 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 BWK49_RS16945 57f8c52b0f58401899942a0b92c733d5 405 SUPERFAMILY SSF69864 172 397 3.92E-85 T 06-07-2017 BWK49_RS16945 57f8c52b0f58401899942a0b92c733d5 405 SUPERFAMILY SSF52402 3 171 7.5E-41 T 06-07-2017 BWK49_RS08960 752a7fa030c7b3b0639e79e80497bba5 551 SUPERFAMILY SSF47917 383 511 1.78E-46 T 06-07-2017 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 BWK49_RS08960 752a7fa030c7b3b0639e79e80497bba5 551 SUPERFAMILY SSF50615 14 97 4.51E-25 T 06-07-2017 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 BWK49_RS08960 752a7fa030c7b3b0639e79e80497bba5 551 SUPERFAMILY SSF52540 99 381 2.95E-95 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS08960 752a7fa030c7b3b0639e79e80497bba5 551 Gene3D G3DSA:2.40.30.20 6 96 2.3E-30 T 06-07-2017 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 BWK49_RS08960 752a7fa030c7b3b0639e79e80497bba5 551 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 29 95 5.3E-17 T 06-07-2017 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 BWK49_RS08960 752a7fa030c7b3b0639e79e80497bba5 551 Gene3D G3DSA:1.20.150.20 383 511 1.8E-53 T 06-07-2017 BWK49_RS08960 752a7fa030c7b3b0639e79e80497bba5 551 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 4 512 49.96 T 06-07-2017 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 BWK49_RS08960 752a7fa030c7b3b0639e79e80497bba5 551 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 382 507 7.3E-49 T 06-07-2017 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 BWK49_RS08960 752a7fa030c7b3b0639e79e80497bba5 551 Gene3D G3DSA:3.40.50.300 98 382 6.1E-111 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS08960 752a7fa030c7b3b0639e79e80497bba5 551 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 7 512 1.9E-254 T 06-07-2017 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 BWK49_RS08960 752a7fa030c7b3b0639e79e80497bba5 551 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 366 375 - T 06-07-2017 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 BWK49_RS08960 752a7fa030c7b3b0639e79e80497bba5 551 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 152 375 2.8E-69 T 06-07-2017 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 BWK49_RS08960 752a7fa030c7b3b0639e79e80497bba5 551 PIRSF PIRSF039088 4 514 1.1E-234 T 06-07-2017 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 BWK49_RS24875 8a727d784800dac2ec185eeff7a1e384 528 Gene3D G3DSA:3.40.50.720 5 249 2.9E-44 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS24875 8a727d784800dac2ec185eeff7a1e384 528 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 195 2.2E-4 T 06-07-2017 BWK49_RS24875 8a727d784800dac2ec185eeff7a1e384 528 Pfam PF00106 short chain dehydrogenase 7 198 3.0E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS24875 8a727d784800dac2ec185eeff7a1e384 528 SUPERFAMILY SSF51735 5 256 1.11E-41 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS24875 8a727d784800dac2ec185eeff7a1e384 528 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 137 153 3.3E-20 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS24875 8a727d784800dac2ec185eeff7a1e384 528 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 3.3E-20 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS24875 8a727d784800dac2ec185eeff7a1e384 528 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 181 3.3E-20 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS24875 8a727d784800dac2ec185eeff7a1e384 528 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 90 101 3.3E-20 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS24875 8a727d784800dac2ec185eeff7a1e384 528 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 3.3E-20 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS24875 8a727d784800dac2ec185eeff7a1e384 528 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 3.3E-20 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS09405 85f99b8a0ee35fb5843c1505c4330b24 539 SUPERFAMILY SSF51905 320 536 1.59E-29 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS09405 85f99b8a0ee35fb5843c1505c4330b24 539 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 178 203 8.7E-5 T 06-07-2017 BWK49_RS09405 85f99b8a0ee35fb5843c1505c4330b24 539 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 9 31 8.7E-5 T 06-07-2017 BWK49_RS09405 85f99b8a0ee35fb5843c1505c4330b24 539 SUPERFAMILY SSF51905 5 216 1.53E-47 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS09405 85f99b8a0ee35fb5843c1505c4330b24 539 Gene3D G3DSA:3.50.50.60 5 181 3.7E-72 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS09405 85f99b8a0ee35fb5843c1505c4330b24 539 Gene3D G3DSA:3.50.50.60 424 535 3.7E-72 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS09405 85f99b8a0ee35fb5843c1505c4330b24 539 Gene3D G3DSA:3.40.50.720 182 214 2.9E-5 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS09405 85f99b8a0ee35fb5843c1505c4330b24 539 Gene3D G3DSA:3.40.50.720 351 386 2.9E-5 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS09405 85f99b8a0ee35fb5843c1505c4330b24 539 SUPERFAMILY SSF51905 147 383 5.83E-42 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS09405 85f99b8a0ee35fb5843c1505c4330b24 539 Pfam PF00743 Flavin-binding monooxygenase-like 10 210 5.0E-12 T 06-07-2017 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 BWK49_RS18235 8cc8ae03cf0645839b8014e574aaeddd 309 SUPERFAMILY SSF52768 2 307 4.8E-103 T 06-07-2017 BWK49_RS18235 8cc8ae03cf0645839b8014e574aaeddd 309 Gene3D G3DSA:3.40.800.20 3 307 3.0E-107 T 06-07-2017 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 BWK49_RS18235 8cc8ae03cf0645839b8014e574aaeddd 309 PRINTS PR01270 Histone deacetylase superfamily signature 236 246 4.7E-17 T 06-07-2017 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 BWK49_RS18235 8cc8ae03cf0645839b8014e574aaeddd 309 PRINTS PR01270 Histone deacetylase superfamily signature 122 145 4.7E-17 T 06-07-2017 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 BWK49_RS18235 8cc8ae03cf0645839b8014e574aaeddd 309 PRINTS PR01270 Histone deacetylase superfamily signature 156 171 4.7E-17 T 06-07-2017 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 BWK49_RS18235 8cc8ae03cf0645839b8014e574aaeddd 309 Pfam PF00850 Histone deacetylase domain 20 305 7.4E-90 T 06-07-2017 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 BWK49_RS05770 039f9fdf4170c9fd82ec1a298f9d2564 268 Pfam PF13847 Methyltransferase domain 36 172 1.1E-26 T 06-07-2017 IPR025714 Methyltransferase domain BWK49_RS05770 039f9fdf4170c9fd82ec1a298f9d2564 268 Gene3D G3DSA:3.40.50.150 7 218 8.1E-44 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS05770 039f9fdf4170c9fd82ec1a298f9d2564 268 SUPERFAMILY SSF53335 5 251 3.72E-45 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS13810 26e6bd5a4a7579c8f4d76f6f7d9fbffb 438 TIGRFAM TIGR01412 tat_substr_1: Tat-translocated enzyme 21 438 5.6E-131 T 06-07-2017 IPR006313 Deferrochelatase/peroxidase EfeB GO:0004601|GO:0015684|GO:0020037|GO:0033212 BWK49_RS13810 26e6bd5a4a7579c8f4d76f6f7d9fbffb 438 SUPERFAMILY SSF54909 80 432 3.22E-86 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel BWK49_RS13810 26e6bd5a4a7579c8f4d76f6f7d9fbffb 438 Pfam PF04261 Dyp-type peroxidase family 82 426 1.4E-91 T 06-07-2017 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 BWK49_RS13810 26e6bd5a4a7579c8f4d76f6f7d9fbffb 438 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 82 426 5.2E-79 T 06-07-2017 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 BWK49_RS22455 ca6a93ea058f8ae578ca0136a2c54e04 532 SUPERFAMILY SSF50475 24 322 4.71E-81 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 BWK49_RS22455 ca6a93ea058f8ae578ca0136a2c54e04 532 Gene3D G3DSA:3.40.1670.10 352 469 2.0E-20 T 06-07-2017 BWK49_RS22455 ca6a93ea058f8ae578ca0136a2c54e04 532 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 25 455 8.8E-80 T 06-07-2017 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 BWK49_RS22455 ca6a93ea058f8ae578ca0136a2c54e04 532 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 29 425 5.5E-108 T 06-07-2017 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 BWK49_RS22455 ca6a93ea058f8ae578ca0136a2c54e04 532 SUPERFAMILY SSF143968 330 507 9.94E-31 T 06-07-2017 BWK49_RS23130 be560ab5abb94f851897b00b9b4e1dee 389 Gene3D G3DSA:1.20.140.10 226 389 1.1E-68 T 06-07-2017 BWK49_RS23130 be560ab5abb94f851897b00b9b4e1dee 389 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 17 126 6.1E-30 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS23130 be560ab5abb94f851897b00b9b4e1dee 389 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 238 387 3.2E-48 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS23130 be560ab5abb94f851897b00b9b4e1dee 389 Gene3D G3DSA:2.40.110.10 131 225 5.9E-39 T 06-07-2017 BWK49_RS23130 be560ab5abb94f851897b00b9b4e1dee 389 SUPERFAMILY SSF56645 13 250 1.44E-76 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS23130 be560ab5abb94f851897b00b9b4e1dee 389 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 346 365 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 BWK49_RS23130 be560ab5abb94f851897b00b9b4e1dee 389 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 133 145 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 BWK49_RS23130 be560ab5abb94f851897b00b9b4e1dee 389 Gene3D G3DSA:1.10.540.10 13 127 1.4E-35 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS23130 be560ab5abb94f851897b00b9b4e1dee 389 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 131 226 6.1E-29 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 BWK49_RS23130 be560ab5abb94f851897b00b9b4e1dee 389 SUPERFAMILY SSF47203 236 389 9.34E-57 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS24955 2c56dfe8ac4902b372d101a6a79d5b02 542 Gene3D G3DSA:3.30.300.30 400 497 1.5E-10 T 06-07-2017 BWK49_RS24955 2c56dfe8ac4902b372d101a6a79d5b02 542 Pfam PF00501 AMP-binding enzyme 19 399 1.1E-59 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS24955 2c56dfe8ac4902b372d101a6a79d5b02 542 Gene3D G3DSA:3.40.50.980 161 298 2.6E-20 T 06-07-2017 BWK49_RS24955 2c56dfe8ac4902b372d101a6a79d5b02 542 Gene3D G3DSA:2.30.38.10 306 393 2.6E-17 T 06-07-2017 BWK49_RS24955 2c56dfe8ac4902b372d101a6a79d5b02 542 ProSitePatterns PS00455 Putative AMP-binding domain signature. 153 164 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS24955 2c56dfe8ac4902b372d101a6a79d5b02 542 SUPERFAMILY SSF56801 18 497 1.23E-95 T 06-07-2017 BWK49_RS24955 2c56dfe8ac4902b372d101a6a79d5b02 542 Gene3D G3DSA:3.40.50.980 18 160 8.9E-20 T 06-07-2017 BWK49_RS09475 80c0856a42f918281fe373e8e55cd40f 414 Gene3D G3DSA:1.20.140.10 223 394 5.2E-19 T 06-07-2017 BWK49_RS09475 80c0856a42f918281fe373e8e55cd40f 414 SUPERFAMILY SSF47203 233 392 3.81E-12 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS09475 80c0856a42f918281fe373e8e55cd40f 414 Gene3D G3DSA:2.40.110.10 129 222 6.5E-28 T 06-07-2017 BWK49_RS09475 80c0856a42f918281fe373e8e55cd40f 414 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 4 123 6.3E-13 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS09475 80c0856a42f918281fe373e8e55cd40f 414 Gene3D G3DSA:1.10.540.10 3 124 1.3E-17 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS09475 80c0856a42f918281fe373e8e55cd40f 414 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 130 206 6.5E-19 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 BWK49_RS09475 80c0856a42f918281fe373e8e55cd40f 414 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 233 388 1.2E-11 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS09475 80c0856a42f918281fe373e8e55cd40f 414 SUPERFAMILY SSF56645 4 245 2.36E-57 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS15885 8c5020cc8710a909344c86a1f0df74c4 461 SMART SM00507 352 404 5.2E-4 T 06-07-2017 IPR003615 HNH nuclease BWK49_RS15885 8c5020cc8710a909344c86a1f0df74c4 461 ProDom PD008243 RV1792C/MT1741/MB1728C RV1945/MT1995 MB1980 MB0098C RV3466/MT3572 VERY RV1128C/MT1160 RV1148C/MT1183 MB1159C RV0095C 31 96 4.0E-5 T 06-07-2017 BWK49_RS15885 8c5020cc8710a909344c86a1f0df74c4 461 Pfam PF02720 Domain of unknown function (DUF222) 38 361 2.5E-92 T 06-07-2017 IPR003870 Domain of unknown function DUF222 BWK49_RS15685 3cd11cba0ddcb4677f1d36895eb057c5 888 ProSitePatterns PS00211 ABC transporters family signature. 477 491 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 BWK49_RS15685 3cd11cba0ddcb4677f1d36895eb057c5 888 SUPERFAMILY SSF52540 338 556 5.43E-54 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS15685 3cd11cba0ddcb4677f1d36895eb057c5 888 Gene3D G3DSA:2.60.200.20 133 171 3.6E-21 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 BWK49_RS15685 3cd11cba0ddcb4677f1d36895eb057c5 888 Gene3D G3DSA:2.60.200.20 244 333 3.6E-21 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 BWK49_RS15685 3cd11cba0ddcb4677f1d36895eb057c5 888 SUPERFAMILY SSF49879 194 323 7.65E-25 T 06-07-2017 IPR008984 SMAD/FHA domain GO:0005515 BWK49_RS15685 3cd11cba0ddcb4677f1d36895eb057c5 888 Pfam PF00498 FHA domain 253 316 4.9E-15 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 BWK49_RS15685 3cd11cba0ddcb4677f1d36895eb057c5 888 Pfam PF00498 FHA domain 16 79 4.6E-12 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 BWK49_RS15685 3cd11cba0ddcb4677f1d36895eb057c5 888 Pfam PF01061 ABC-2 type transporter 619 832 1.6E-19 T 06-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 BWK49_RS15685 3cd11cba0ddcb4677f1d36895eb057c5 888 Gene3D G3DSA:2.60.200.20 7 80 8.3E-16 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 BWK49_RS15685 3cd11cba0ddcb4677f1d36895eb057c5 888 SUPERFAMILY SSF49879 12 107 3.25E-19 T 06-07-2017 IPR008984 SMAD/FHA domain GO:0005515 BWK49_RS15685 3cd11cba0ddcb4677f1d36895eb057c5 888 Gene3D G3DSA:3.40.50.300 335 562 2.6E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS15685 3cd11cba0ddcb4677f1d36895eb057c5 888 Pfam PF00005 ABC transporter 358 505 5.9E-31 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 BWK49_RS15685 3cd11cba0ddcb4677f1d36895eb057c5 888 SMART SM00382 367 551 4.5E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS15685 3cd11cba0ddcb4677f1d36895eb057c5 888 SMART SM00240 252 302 7.0E-15 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 BWK49_RS15685 3cd11cba0ddcb4677f1d36895eb057c5 888 SMART SM00240 15 65 5.9E-10 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 BWK49_RS03045 5e54ddc469e5cae138a68bf445a111b5 137 Gene3D G3DSA:3.10.180.10 1 133 8.4E-20 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS03045 5e54ddc469e5cae138a68bf445a111b5 137 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 2 132 1.0E-10 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain BWK49_RS03045 5e54ddc469e5cae138a68bf445a111b5 137 SUPERFAMILY SSF54593 1 136 3.16E-19 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS12060 4543209b39d91ec8bd000bb49298c7f5 161 SUPERFAMILY SSF46785 12 148 5.29E-32 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS12060 4543209b39d91ec8bd000bb49298c7f5 161 Gene3D G3DSA:1.10.10.10 4 148 3.0E-34 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS12060 4543209b39d91ec8bd000bb49298c7f5 161 SMART SM00347 36 136 1.9E-20 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 BWK49_RS12060 4543209b39d91ec8bd000bb49298c7f5 161 Pfam PF01047 MarR family 48 101 1.1E-11 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 BWK49_RS12060 4543209b39d91ec8bd000bb49298c7f5 161 PRINTS PR00598 Bacterial regulatory protein MarR family signature 60 76 7.5E-16 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 BWK49_RS12060 4543209b39d91ec8bd000bb49298c7f5 161 PRINTS PR00598 Bacterial regulatory protein MarR family signature 77 92 7.5E-16 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 BWK49_RS12060 4543209b39d91ec8bd000bb49298c7f5 161 PRINTS PR00598 Bacterial regulatory protein MarR family signature 126 146 7.5E-16 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 BWK49_RS12060 4543209b39d91ec8bd000bb49298c7f5 161 PRINTS PR00598 Bacterial regulatory protein MarR family signature 96 112 7.5E-16 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 BWK49_RS22575 09b65f59854ae43f4a97ddd112ca3a09 899 SUPERFAMILY SSF52540 118 219 2.66E-8 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS22575 09b65f59854ae43f4a97ddd112ca3a09 899 SUPERFAMILY SSF52540 9 76 2.66E-8 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS22575 09b65f59854ae43f4a97ddd112ca3a09 899 Pfam PF13191 AAA ATPase domain 1 149 1.2E-16 T 06-07-2017 BWK49_RS22575 09b65f59854ae43f4a97ddd112ca3a09 899 SMART SM00421 842 899 1.3E-19 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS22575 09b65f59854ae43f4a97ddd112ca3a09 899 Gene3D G3DSA:1.10.10.10 843 895 1.4E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS22575 09b65f59854ae43f4a97ddd112ca3a09 899 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 859 875 8.0E-9 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS22575 09b65f59854ae43f4a97ddd112ca3a09 899 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 845 859 8.0E-9 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS22575 09b65f59854ae43f4a97ddd112ca3a09 899 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 875 887 8.0E-9 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS22575 09b65f59854ae43f4a97ddd112ca3a09 899 SUPERFAMILY SSF46894 840 897 9.18E-15 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 BWK49_RS22575 09b65f59854ae43f4a97ddd112ca3a09 899 Pfam PF00196 Bacterial regulatory proteins, luxR family 844 895 3.9E-14 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS22575 09b65f59854ae43f4a97ddd112ca3a09 899 Gene3D G3DSA:1.25.40.10 350 427 2.3E-6 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 BWK49_RS22575 09b65f59854ae43f4a97ddd112ca3a09 899 Gene3D G3DSA:1.25.40.10 588 809 2.3E-6 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 BWK49_RS22575 09b65f59854ae43f4a97ddd112ca3a09 899 Gene3D G3DSA:3.40.50.300 8 171 2.2E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS12365 09d09c2ecf7aa3b655807318523d997c 118 Pfam PF05423 Mycobacterium membrane protein 36 116 2.3E-8 T 06-07-2017 IPR008693 Transport accessory protein MmpS BWK49_RS18510 344b49668bedec56321d4eebeb351db4 904 SMART SM00567 E-Z type HEAT repeats 853 883 28.0 T 06-07-2017 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 BWK49_RS18510 344b49668bedec56321d4eebeb351db4 904 SMART SM00567 E-Z type HEAT repeats 822 851 6.5 T 06-07-2017 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 BWK49_RS18510 344b49668bedec56321d4eebeb351db4 904 SMART SM00567 E-Z type HEAT repeats 729 755 1200.0 T 06-07-2017 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 BWK49_RS18510 344b49668bedec56321d4eebeb351db4 904 SMART SM00567 E-Z type HEAT repeats 790 820 370.0 T 06-07-2017 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 BWK49_RS18510 344b49668bedec56321d4eebeb351db4 904 SMART SM00567 E-Z type HEAT repeats 636 665 2.5 T 06-07-2017 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 BWK49_RS18510 344b49668bedec56321d4eebeb351db4 904 SUPERFAMILY SSF48371 718 865 4.85E-28 T 06-07-2017 IPR016024 Armadillo-type fold GO:0005488 BWK49_RS18510 344b49668bedec56321d4eebeb351db4 904 SUPERFAMILY SSF48371 621 685 4.85E-28 T 06-07-2017 IPR016024 Armadillo-type fold GO:0005488 BWK49_RS18510 344b49668bedec56321d4eebeb351db4 904 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 378 385 5.1E-8 T 06-07-2017 BWK49_RS18510 344b49668bedec56321d4eebeb351db4 904 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 16 38 5.1E-8 T 06-07-2017 BWK49_RS18510 344b49668bedec56321d4eebeb351db4 904 Pfam PF00890 FAD binding domain 16 387 2.7E-38 T 06-07-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 BWK49_RS18510 344b49668bedec56321d4eebeb351db4 904 Pfam PF02910 Fumarate reductase flavoprotein C-term 449 563 2.6E-11 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 BWK49_RS18510 344b49668bedec56321d4eebeb351db4 904 SUPERFAMILY SSF51905 4 268 1.67E-60 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS18510 344b49668bedec56321d4eebeb351db4 904 SUPERFAMILY SSF51905 364 436 1.67E-60 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS18510 344b49668bedec56321d4eebeb351db4 904 SUPERFAMILY SSF46977 434 561 3.27E-34 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 BWK49_RS18510 344b49668bedec56321d4eebeb351db4 904 Gene3D G3DSA:1.20.58.100 425 531 4.3E-33 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 BWK49_RS18510 344b49668bedec56321d4eebeb351db4 904 Gene3D G3DSA:1.25.10.10 632 896 4.5E-32 T 06-07-2017 IPR011989 Armadillo-like helical BWK49_RS18510 344b49668bedec56321d4eebeb351db4 904 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 363 385 4.7E-12 T 06-07-2017 BWK49_RS18510 344b49668bedec56321d4eebeb351db4 904 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 17 36 4.7E-12 T 06-07-2017 BWK49_RS18510 344b49668bedec56321d4eebeb351db4 904 Pfam PF13646 HEAT repeats 813 895 1.6E-9 T 06-07-2017 BWK49_RS18510 344b49668bedec56321d4eebeb351db4 904 Gene3D G3DSA:3.50.50.60 11 285 2.3E-72 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS18510 344b49668bedec56321d4eebeb351db4 904 Gene3D G3DSA:3.50.50.60 364 424 2.3E-72 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS25085 989402fc7c3750085029f1b15c303fba 221 SUPERFAMILY SSF53448 10 204 1.07E-22 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases BWK49_RS25085 989402fc7c3750085029f1b15c303fba 221 Gene3D G3DSA:3.90.550.10 8 190 2.3E-20 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases BWK49_RS25085 989402fc7c3750085029f1b15c303fba 221 Pfam PF09837 Uncharacterized protein conserved in bacteria (DUF2064) 44 165 2.2E-29 T 06-07-2017 IPR018641 Transferase 1, rSAM/selenodomain-associated BWK49_RS14035 56289f65851aa578f8c734e6d545eb20 275 Gene3D G3DSA:3.20.20.80 61 227 1.2E-12 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 BWK49_RS14035 56289f65851aa578f8c734e6d545eb20 275 SUPERFAMILY SSF51445 61 204 2.95E-6 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily BWK49_RS14035 56289f65851aa578f8c734e6d545eb20 275 Pfam PF08924 Domain of unknown function (DUF1906) 61 188 4.5E-25 T 06-07-2017 IPR015020 Protein of unknown function DUF1906 BWK49_RS23205 c910995c1e0976c9aadcae5607829f7a 600 SUPERFAMILY SSF56059 90 337 6.01E-58 T 06-07-2017 BWK49_RS23205 c910995c1e0976c9aadcae5607829f7a 600 SUPERFAMILY SSF51246 336 456 1.05E-37 T 06-07-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 BWK49_RS23205 c910995c1e0976c9aadcae5607829f7a 600 Gene3D G3DSA:3.30.470.20 210 456 5.9E-92 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 BWK49_RS23205 c910995c1e0976c9aadcae5607829f7a 600 Gene3D G3DSA:3.40.50.20 9 136 1.2E-46 T 06-07-2017 IPR016185 Pre-ATP-grasp domain BWK49_RS23205 c910995c1e0976c9aadcae5607829f7a 600 Pfam PF00289 Biotin carboxylase, N-terminal domain 9 117 1.1E-42 T 06-07-2017 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 BWK49_RS23205 c910995c1e0976c9aadcae5607829f7a 600 Pfam PF02785 Biotin carboxylase C-terminal domain 342 452 3.4E-35 T 06-07-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 BWK49_RS23205 c910995c1e0976c9aadcae5607829f7a 600 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 160 174 - T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 BWK49_RS23205 c910995c1e0976c9aadcae5607829f7a 600 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 122 329 2.8E-80 T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 BWK49_RS23205 c910995c1e0976c9aadcae5607829f7a 600 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 293 300 - T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 BWK49_RS23205 c910995c1e0976c9aadcae5607829f7a 600 SUPERFAMILY SSF52440 7 120 1.44E-45 T 06-07-2017 IPR016185 Pre-ATP-grasp domain BWK49_RS23205 c910995c1e0976c9aadcae5607829f7a 600 Gene3D G3DSA:3.30.1490.20 137 209 4.6E-24 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 BWK49_RS23205 c910995c1e0976c9aadcae5607829f7a 600 Pfam PF00364 Biotin-requiring enzyme 534 599 6.2E-18 T 06-07-2017 IPR000089 Biotin/lipoyl attachment BWK49_RS23205 c910995c1e0976c9aadcae5607829f7a 600 SMART SM00878 342 452 1.2E-57 T 06-07-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 BWK49_RS23205 c910995c1e0976c9aadcae5607829f7a 600 SUPERFAMILY SSF51230 528 599 1.44E-20 T 06-07-2017 IPR011053 Single hybrid motif BWK49_RS23205 c910995c1e0976c9aadcae5607829f7a 600 Gene3D G3DSA:2.40.50.100 530 600 7.5E-24 T 06-07-2017 BWK49_RS23205 c910995c1e0976c9aadcae5607829f7a 600 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 556 573 - T 06-07-2017 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 BWK49_RS04970 f8cfa20ded6707d629c9a820a81f47f2 287 SUPERFAMILY SSF51735 1 268 3.4E-68 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS04970 f8cfa20ded6707d629c9a820a81f47f2 287 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 197 2.3E-4 T 06-07-2017 BWK49_RS04970 f8cfa20ded6707d629c9a820a81f47f2 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 6.8E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS04970 f8cfa20ded6707d629c9a820a81f47f2 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 6.8E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS04970 f8cfa20ded6707d629c9a820a81f47f2 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 6.8E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS04970 f8cfa20ded6707d629c9a820a81f47f2 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 6.8E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS04970 f8cfa20ded6707d629c9a820a81f47f2 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 6.8E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS04970 f8cfa20ded6707d629c9a820a81f47f2 287 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 4.2E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS04970 f8cfa20ded6707d629c9a820a81f47f2 287 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 4.2E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS04970 f8cfa20ded6707d629c9a820a81f47f2 287 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 4.2E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS04970 f8cfa20ded6707d629c9a820a81f47f2 287 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS04970 f8cfa20ded6707d629c9a820a81f47f2 287 Pfam PF00106 short chain dehydrogenase 7 197 1.6E-51 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS04970 f8cfa20ded6707d629c9a820a81f47f2 287 Gene3D G3DSA:3.40.50.720 6 239 4.5E-67 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS23425 a5efa59685c1aafceffb6c2f918af2a8 145 SUPERFAMILY SSF81343 18 134 4.19E-28 T 06-07-2017 BWK49_RS23425 a5efa59685c1aafceffb6c2f918af2a8 145 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 19 129 1.1E-23 T 06-07-2017 IPR000701 Succinate dehydrogenase/Fumarate reductase, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 BWK49_RS23425 a5efa59685c1aafceffb6c2f918af2a8 145 TIGRFAM TIGR02970 succ_dehyd_cytB: succinate dehydrogenase, cytochrome b556 subunit 26 134 6.3E-28 T 06-07-2017 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 BWK49_RS23425 a5efa59685c1aafceffb6c2f918af2a8 145 Gene3D G3DSA:1.20.1300.10 18 135 3.1E-30 T 06-07-2017 BWK49_RS07735 e5681073b3c8709c89a899e42367cb6a 392 SUPERFAMILY SSF53383 16 391 7.29E-115 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase BWK49_RS07735 e5681073b3c8709c89a899e42367cb6a 392 Gene3D G3DSA:3.90.1150.10 261 391 3.1E-51 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 BWK49_RS07735 e5681073b3c8709c89a899e42367cb6a 392 Gene3D G3DSA:3.40.640.10 13 260 1.4E-92 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 BWK49_RS07735 e5681073b3c8709c89a899e42367cb6a 392 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 204 218 - T 06-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 BWK49_RS07735 e5681073b3c8709c89a899e42367cb6a 392 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 15 391 3.0E-145 T 06-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 BWK49_RS07735 e5681073b3c8709c89a899e42367cb6a 392 PIRSF PIRSF001434 2 392 5.3E-144 T 06-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 BWK49_RS16970 f1dca5ebc4b1a6b28b57ca245655f5c8 403 SUPERFAMILY SSF56266 18 399 1.22E-122 T 06-07-2017 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 BWK49_RS16970 f1dca5ebc4b1a6b28b57ca245655f5c8 403 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 13 402 1.8E-110 T 06-07-2017 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 BWK49_RS16970 f1dca5ebc4b1a6b28b57ca245655f5c8 403 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 403 133.836 T 06-07-2017 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 BWK49_RS16970 f1dca5ebc4b1a6b28b57ca245655f5c8 403 Gene3D G3DSA:3.60.70.12 12 279 2.0E-93 T 06-07-2017 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 BWK49_RS16970 f1dca5ebc4b1a6b28b57ca245655f5c8 403 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 37 401 1.0E-175 T 06-07-2017 BWK49_RS16970 f1dca5ebc4b1a6b28b57ca245655f5c8 403 Pfam PF01960 ArgJ family 23 403 3.0E-128 T 06-07-2017 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 BWK49_RS22300 2e3e548a87ced1d4cfbcc6894bddbd80 150 SMART SM00422 18 86 8.3E-25 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 BWK49_RS22300 2e3e548a87ced1d4cfbcc6894bddbd80 150 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 19 30 1.8E-6 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 BWK49_RS22300 2e3e548a87ced1d4cfbcc6894bddbd80 150 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 53 73 1.8E-6 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 BWK49_RS22300 2e3e548a87ced1d4cfbcc6894bddbd80 150 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 30 43 1.8E-6 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 BWK49_RS22300 2e3e548a87ced1d4cfbcc6894bddbd80 150 SUPERFAMILY SSF46955 18 104 3.53E-21 T 06-07-2017 IPR009061 Putative DNA-binding domain BWK49_RS22300 2e3e548a87ced1d4cfbcc6894bddbd80 150 Gene3D G3DSA:1.10.1660.10 19 112 2.0E-23 T 06-07-2017 BWK49_RS22300 2e3e548a87ced1d4cfbcc6894bddbd80 150 Pfam PF13411 MerR HTH family regulatory protein 18 84 8.4E-17 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 BWK49_RS21685 3621d0f6a159dc49a9a65b914eb76f2a 198 SUPERFAMILY SSF48498 95 191 5.34E-6 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS21685 3621d0f6a159dc49a9a65b914eb76f2a 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 69 1.2E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS21685 3621d0f6a159dc49a9a65b914eb76f2a 198 Gene3D G3DSA:1.10.357.10 13 198 6.7E-31 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS21685 3621d0f6a159dc49a9a65b914eb76f2a 198 SUPERFAMILY SSF46689 12 86 9.22E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS18520 559f5871ed4630dbaabb17099fa36685 285 Gene3D G3DSA:1.10.3720.10 81 275 6.9E-20 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS18520 559f5871ed4630dbaabb17099fa36685 285 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 104 274 4.3E-17 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS18520 559f5871ed4630dbaabb17099fa36685 285 SUPERFAMILY SSF161098 80 261 4.97E-26 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS12385 09b64a85e3463585fe7cbbdead20bd45 364 Gene3D G3DSA:3.40.50.150 245 298 2.6E-47 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS12385 09b64a85e3463585fe7cbbdead20bd45 364 Gene3D G3DSA:3.40.50.150 25 208 2.6E-47 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS12385 09b64a85e3463585fe7cbbdead20bd45 364 SUPERFAMILY SSF53335 18 359 1.38E-73 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS12385 09b64a85e3463585fe7cbbdead20bd45 364 Pfam PF03492 SAM dependent carboxyl methyltransferase 49 333 8.9E-36 T 06-07-2017 IPR005299 SAM dependent carboxyl methyltransferase GO:0008168 BWK49_RS18320 46a9172ee3d5e4621b563112079a8cf6 651 SMART SM00278 618 637 0.38 T 06-07-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 BWK49_RS18320 46a9172ee3d5e4621b563112079a8cf6 651 SMART SM00278 586 605 140.0 T 06-07-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 BWK49_RS18320 46a9172ee3d5e4621b563112079a8cf6 651 Pfam PF02151 UvrB/uvrC motif 210 242 2.3E-9 T 06-07-2017 IPR001943 UVR domain GO:0005515 BWK49_RS18320 46a9172ee3d5e4621b563112079a8cf6 651 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 404 572 7.0E-50 T 06-07-2017 IPR001162 UvrC family homology region BWK49_RS18320 46a9172ee3d5e4621b563112079a8cf6 651 Hamap MF_00203 UvrABC system protein C [uvrC]. 4 637 30.991 T 06-07-2017 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 BWK49_RS18320 46a9172ee3d5e4621b563112079a8cf6 651 SMART SM00465 17 99 4.5E-22 T 06-07-2017 IPR000305 GIY-YIG nuclease superfamily BWK49_RS18320 46a9172ee3d5e4621b563112079a8cf6 651 Pfam PF14520 Helix-hairpin-helix domain 588 639 1.0E-10 T 06-07-2017 BWK49_RS18320 46a9172ee3d5e4621b563112079a8cf6 651 Gene3D G3DSA:4.10.860.10 187 248 2.0E-19 T 06-07-2017 IPR001943 UVR domain GO:0005515 BWK49_RS18320 46a9172ee3d5e4621b563112079a8cf6 651 SUPERFAMILY SSF82771 18 101 2.62E-22 T 06-07-2017 IPR000305 GIY-YIG nuclease superfamily BWK49_RS18320 46a9172ee3d5e4621b563112079a8cf6 651 SUPERFAMILY SSF47781 526 641 9.21E-25 T 06-07-2017 IPR010994 RuvA domain 2-like BWK49_RS18320 46a9172ee3d5e4621b563112079a8cf6 651 Gene3D G3DSA:3.40.1440.10 17 95 8.9E-10 T 06-07-2017 IPR027299 GIY-YIG domain BWK49_RS18320 46a9172ee3d5e4621b563112079a8cf6 651 SUPERFAMILY SSF46600 194 247 1.44E-14 T 06-07-2017 IPR001943 UVR domain GO:0005515 BWK49_RS18320 46a9172ee3d5e4621b563112079a8cf6 651 Gene3D G3DSA:1.10.150.20 586 639 4.7E-20 T 06-07-2017 BWK49_RS18320 46a9172ee3d5e4621b563112079a8cf6 651 Pfam PF01541 GIY-YIG catalytic domain 18 92 5.4E-11 T 06-07-2017 IPR000305 GIY-YIG nuclease superfamily BWK49_RS18320 46a9172ee3d5e4621b563112079a8cf6 651 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 13 619 6.7E-155 T 06-07-2017 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 BWK49_RS16915 e39f989ee19eed1bd72509e3864e7aa9 353 PIRSF PIRSF000451 1 353 6.0E-110 T 06-07-2017 IPR011141 Polyketide synthase, type III GO:0009058|GO:0016747 BWK49_RS16915 e39f989ee19eed1bd72509e3864e7aa9 353 Pfam PF02797 Chalcone and stilbene synthases, C-terminal domain 219 351 1.2E-12 T 06-07-2017 IPR012328 Chalcone/stilbene synthase, C-terminal BWK49_RS16915 e39f989ee19eed1bd72509e3864e7aa9 353 Pfam PF00195 Chalcone and stilbene synthases, N-terminal domain 38 197 3.4E-20 T 06-07-2017 IPR001099 Chalcone/stilbene synthase, N-terminal BWK49_RS16915 e39f989ee19eed1bd72509e3864e7aa9 353 Gene3D G3DSA:3.40.47.10 211 352 1.9E-30 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS16915 e39f989ee19eed1bd72509e3864e7aa9 353 SUPERFAMILY SSF53901 3 352 2.5E-51 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS16915 e39f989ee19eed1bd72509e3864e7aa9 353 Gene3D G3DSA:3.40.47.10 2 205 2.1E-52 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS20925 3d97b8efa941e5dfaeb9f99002c23a3a 475 Pfam PF13450 NAD(P)-binding Rossmann-like domain 5 54 2.2E-8 T 06-07-2017 BWK49_RS20925 3d97b8efa941e5dfaeb9f99002c23a3a 475 Gene3D G3DSA:3.50.50.60 409 464 6.9E-19 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS20925 3d97b8efa941e5dfaeb9f99002c23a3a 475 Gene3D G3DSA:3.50.50.60 206 250 6.9E-19 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS20925 3d97b8efa941e5dfaeb9f99002c23a3a 475 Gene3D G3DSA:3.50.50.60 1 52 6.9E-19 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS20925 3d97b8efa941e5dfaeb9f99002c23a3a 475 Gene3D G3DSA:3.50.50.60 342 343 6.9E-19 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS20925 3d97b8efa941e5dfaeb9f99002c23a3a 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 324 345 7.8E-6 T 06-07-2017 BWK49_RS20925 3d97b8efa941e5dfaeb9f99002c23a3a 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 2 24 7.8E-6 T 06-07-2017 BWK49_RS20925 3d97b8efa941e5dfaeb9f99002c23a3a 475 SUPERFAMILY SSF51905 2 292 1.45E-25 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS20925 3d97b8efa941e5dfaeb9f99002c23a3a 475 SUPERFAMILY SSF51905 433 463 1.45E-25 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS01020 6b55819ca702992ab5f21f979bd86c97 274 Gene3D G3DSA:3.20.20.190 10 265 4.1E-64 T 06-07-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 BWK49_RS01020 6b55819ca702992ab5f21f979bd86c97 274 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 17 258 8.8E-49 T 06-07-2017 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 BWK49_RS01020 6b55819ca702992ab5f21f979bd86c97 274 SUPERFAMILY SSF51695 11 264 6.54E-60 T 06-07-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 BWK49_RS24220 075af8a7118dc28b9180ef405357353d 66 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 2 59 19.591 T 06-07-2017 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 BWK49_RS24220 075af8a7118dc28b9180ef405357353d 66 Gene3D G3DSA:3.30.1390.20 3 58 2.8E-25 T 06-07-2017 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain BWK49_RS24220 075af8a7118dc28b9180ef405357353d 66 Pfam PF00327 Ribosomal protein L30p/L7e 5 55 1.5E-19 T 06-07-2017 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain BWK49_RS24220 075af8a7118dc28b9180ef405357353d 66 SUPERFAMILY SSF55129 4 59 6.02E-20 T 06-07-2017 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain BWK49_RS24220 075af8a7118dc28b9180ef405357353d 66 ProSitePatterns PS00634 Ribosomal protein L30 signature. 23 55 - T 06-07-2017 IPR018038 Ribosomal protein L30, conserved site BWK49_RS24220 075af8a7118dc28b9180ef405357353d 66 PIRSF PIRSF002211 1 60 5.3E-29 T 06-07-2017 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 BWK49_RS24220 075af8a7118dc28b9180ef405357353d 66 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 5 58 3.7E-22 T 06-07-2017 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 BWK49_RS14875 228df8395ffc0e6361fbe8cbce37127b 208 SUPERFAMILY SSF48150 26 153 2.97E-8 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 BWK49_RS14875 228df8395ffc0e6361fbe8cbce37127b 208 Gene3D G3DSA:1.10.340.30 32 144 1.5E-5 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 BWK49_RS23325 bacbebfddebef129514c1c9be6dddd8e 471 Gene3D G3DSA:3.50.50.60 3 148 2.1E-31 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS23325 bacbebfddebef129514c1c9be6dddd8e 471 SUPERFAMILY SSF55424 350 466 1.31E-25 T 06-07-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 BWK49_RS23325 bacbebfddebef129514c1c9be6dddd8e 471 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 332 1.8E-53 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS23325 bacbebfddebef129514c1c9be6dddd8e 471 PIRSF PIRSF000350 1 466 1.2E-71 T 06-07-2017 BWK49_RS23325 bacbebfddebef129514c1c9be6dddd8e 471 Gene3D G3DSA:3.30.390.30 347 464 1.0E-28 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 BWK49_RS23325 bacbebfddebef129514c1c9be6dddd8e 471 Gene3D G3DSA:3.50.50.60 149 341 1.6E-50 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS23325 bacbebfddebef129514c1c9be6dddd8e 471 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 352 460 1.5E-23 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 BWK49_RS23325 bacbebfddebef129514c1c9be6dddd8e 471 SUPERFAMILY SSF51905 3 98 2.09E-49 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS23325 bacbebfddebef129514c1c9be6dddd8e 471 SUPERFAMILY SSF51905 133 341 2.09E-49 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS23325 bacbebfddebef129514c1c9be6dddd8e 471 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 268 284 2.5E-33 T 06-07-2017 BWK49_RS23325 bacbebfddebef129514c1c9be6dddd8e 471 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 2.5E-33 T 06-07-2017 BWK49_RS23325 bacbebfddebef129514c1c9be6dddd8e 471 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 184 202 2.5E-33 T 06-07-2017 BWK49_RS23325 bacbebfddebef129514c1c9be6dddd8e 471 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 297 319 2.5E-33 T 06-07-2017 BWK49_RS23325 bacbebfddebef129514c1c9be6dddd8e 471 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 145 163 2.5E-33 T 06-07-2017 BWK49_RS23325 bacbebfddebef129514c1c9be6dddd8e 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 184 209 7.8E-45 T 06-07-2017 BWK49_RS23325 bacbebfddebef129514c1c9be6dddd8e 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 413 428 7.8E-45 T 06-07-2017 BWK49_RS23325 bacbebfddebef129514c1c9be6dddd8e 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 269 283 7.8E-45 T 06-07-2017 BWK49_RS23325 bacbebfddebef129514c1c9be6dddd8e 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 39 54 7.8E-45 T 06-07-2017 BWK49_RS23325 bacbebfddebef129514c1c9be6dddd8e 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 435 455 7.8E-45 T 06-07-2017 BWK49_RS23325 bacbebfddebef129514c1c9be6dddd8e 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 7.8E-45 T 06-07-2017 BWK49_RS23325 bacbebfddebef129514c1c9be6dddd8e 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 312 319 7.8E-45 T 06-07-2017 BWK49_RS23325 bacbebfddebef129514c1c9be6dddd8e 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 148 157 7.8E-45 T 06-07-2017 BWK49_RS23325 bacbebfddebef129514c1c9be6dddd8e 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 348 369 7.8E-45 T 06-07-2017 BWK49_RS00840 7a7ed7b5f28c61ea16be733f0016293d 442 Gene3D G3DSA:3.30.565.10 293 434 3.0E-29 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS00840 7a7ed7b5f28c61ea16be733f0016293d 442 Gene3D G3DSA:1.10.287.130 214 279 1.8E-10 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 BWK49_RS00840 7a7ed7b5f28c61ea16be733f0016293d 442 SMART SM00387 330 438 7.4E-24 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS00840 7a7ed7b5f28c61ea16be733f0016293d 442 Pfam PF00512 His Kinase A (phospho-acceptor) domain 224 284 2.6E-10 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 BWK49_RS00840 7a7ed7b5f28c61ea16be733f0016293d 442 SMART SM00388 222 288 6.4E-13 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 BWK49_RS00840 7a7ed7b5f28c61ea16be733f0016293d 442 SUPERFAMILY SSF47384 212 284 1.55E-11 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 BWK49_RS00840 7a7ed7b5f28c61ea16be733f0016293d 442 PRINTS PR00344 Bacterial sensor protein C-terminal signature 366 380 3.8E-10 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 BWK49_RS00840 7a7ed7b5f28c61ea16be733f0016293d 442 PRINTS PR00344 Bacterial sensor protein C-terminal signature 398 416 3.8E-10 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 BWK49_RS00840 7a7ed7b5f28c61ea16be733f0016293d 442 PRINTS PR00344 Bacterial sensor protein C-terminal signature 384 394 3.8E-10 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 BWK49_RS00840 7a7ed7b5f28c61ea16be733f0016293d 442 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 332 434 3.5E-20 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS00840 7a7ed7b5f28c61ea16be733f0016293d 442 SUPERFAMILY SSF55874 295 434 6.94E-29 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS26870 b5f881f4f6de174607831058a71330c0 313 SUPERFAMILY SSF47240 18 274 1.32E-48 T 06-07-2017 IPR009078 Ferritin-like superfamily BWK49_RS26870 b5f881f4f6de174607831058a71330c0 313 Pfam PF00268 Ribonucleotide reductase, small chain 28 274 8.6E-16 T 06-07-2017 IPR000358 Ribonucleotide reductase small subunit GO:0009186|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 BWK49_RS26870 b5f881f4f6de174607831058a71330c0 313 Gene3D G3DSA:1.10.620.20 23 276 3.2E-43 T 06-07-2017 IPR012348 Ribonucleotide reductase-related GO:0016491|GO:0055114 Reactome: R-HSA-499943 BWK49_RS13900 42778f34856c7cbf1bd672012b4793ac 967 TIGRFAM TIGR00833 actII: transport protein 31 940 0.0 T 06-07-2017 IPR004707 Membrane transport protein MmpL family GO:0016021 BWK49_RS13900 42778f34856c7cbf1bd672012b4793ac 967 SUPERFAMILY SSF82866 731 940 7.32E-28 T 06-07-2017 BWK49_RS13900 42778f34856c7cbf1bd672012b4793ac 967 Pfam PF03176 MMPL family 64 393 2.2E-107 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 BWK49_RS13900 42778f34856c7cbf1bd672012b4793ac 967 Pfam PF03176 MMPL family 618 949 3.4E-104 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 BWK49_RS13900 42778f34856c7cbf1bd672012b4793ac 967 SUPERFAMILY SSF82866 164 361 9.29E-25 T 06-07-2017 BWK49_RS13900 42778f34856c7cbf1bd672012b4793ac 967 Gene3D G3DSA:1.20.1640.10 162 371 1.8E-24 T 06-07-2017 BWK49_RS13900 42778f34856c7cbf1bd672012b4793ac 967 Gene3D G3DSA:1.20.1640.10 750 944 2.7E-22 T 06-07-2017 BWK49_RS00240 8593d0e521921767a6e5510b2b95b78c 257 Pfam PF08608 Wyosine base formation 183 230 8.3E-7 T 06-07-2017 IPR013917 tRNA wybutosine-synthesis MetaCyc: PWY-7285|MetaCyc: PWY-7286 BWK49_RS00240 8593d0e521921767a6e5510b2b95b78c 257 TIGRFAM TIGR03084 TIGR03084: TIGR03084 family protein 7 257 2.1E-110 T 06-07-2017 IPR017518 Conserved hypothetical protein CHP03084 BWK49_RS00240 8593d0e521921767a6e5510b2b95b78c 257 Gene3D G3DSA:1.20.120.450 6 134 1.4E-9 T 06-07-2017 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase BWK49_RS00240 8593d0e521921767a6e5510b2b95b78c 257 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 11 147 2.2E-29 T 06-07-2017 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 BWK49_RS00240 8593d0e521921767a6e5510b2b95b78c 257 SUPERFAMILY SSF109854 2 152 8.39E-34 T 06-07-2017 BWK49_RS00240 8593d0e521921767a6e5510b2b95b78c 257 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 10 224 2.3E-50 T 06-07-2017 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type BWK49_RS24740 20fe13391ce3702fd915d1650803bbb3 229 Gene3D G3DSA:3.30.450.20 27 127 7.1E-12 T 06-07-2017 BWK49_RS24740 20fe13391ce3702fd915d1650803bbb3 229 SUPERFAMILY SSF52172 146 192 2.04E-5 T 06-07-2017 IPR011006 CheY-like superfamily BWK49_RS24740 20fe13391ce3702fd915d1650803bbb3 229 SMART SM01012 138 193 1.4E-13 T 06-07-2017 IPR005561 ANTAR domain GO:0003723 BWK49_RS24740 20fe13391ce3702fd915d1650803bbb3 229 Pfam PF03861 ANTAR domain 149 192 2.0E-12 T 06-07-2017 IPR005561 ANTAR domain GO:0003723 BWK49_RS24740 20fe13391ce3702fd915d1650803bbb3 229 Gene3D G3DSA:1.10.10.10 148 196 9.8E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS24740 20fe13391ce3702fd915d1650803bbb3 229 Pfam PF08447 PAS fold 36 122 2.8E-11 T 06-07-2017 IPR013655 PAS fold-3 GO:0005515 BWK49_RS24740 20fe13391ce3702fd915d1650803bbb3 229 SUPERFAMILY SSF55785 25 127 6.63E-11 T 06-07-2017 IPR000014 PAS domain BWK49_RS28880 6375ac16ae8ba27f5de1ae5971157202 168 Gene3D G3DSA:1.10.260.40 4 56 7.5E-9 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 BWK49_RS28880 6375ac16ae8ba27f5de1ae5971157202 168 SUPERFAMILY SSF47413 5 50 4.56E-9 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 BWK49_RS28880 6375ac16ae8ba27f5de1ae5971157202 168 Pfam PF13560 Helix-turn-helix domain 5 63 1.7E-8 T 06-07-2017 BWK49_RS28880 6375ac16ae8ba27f5de1ae5971157202 168 SMART SM00530 9 61 2.8E-4 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 BWK49_RS01540 cbe76d357b68194963f84035d5793113 343 Gene3D G3DSA:3.90.180.10 2 163 2.2E-52 T 06-07-2017 IPR011032 GroES-like BWK49_RS01540 cbe76d357b68194963f84035d5793113 343 SMART SM00829 8 339 3.0E-8 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 BWK49_RS01540 cbe76d357b68194963f84035d5793113 343 SUPERFAMILY SSF51735 135 302 4.56E-39 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS01540 cbe76d357b68194963f84035d5793113 343 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 130 2.5E-29 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 BWK49_RS01540 cbe76d357b68194963f84035d5793113 343 Gene3D G3DSA:3.40.50.720 164 283 4.9E-39 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS01540 cbe76d357b68194963f84035d5793113 343 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 58 72 - T 06-07-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 BWK49_RS01540 cbe76d357b68194963f84035d5793113 343 Pfam PF00107 Zinc-binding dehydrogenase 171 300 1.7E-27 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 BWK49_RS01540 cbe76d357b68194963f84035d5793113 343 SUPERFAMILY SSF50129 2 169 2.28E-48 T 06-07-2017 IPR011032 GroES-like BWK49_RS23655 f814716b0257cd65e89d10ff653a24d2 603 SUPERFAMILY SSF52518 364 557 1.61E-50 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS23655 f814716b0257cd65e89d10ff653a24d2 603 Gene3D G3DSA:3.40.50.970 345 553 1.0E-52 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS23655 f814716b0257cd65e89d10ff653a24d2 603 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 198 328 1.3E-22 T 06-07-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 BWK49_RS23655 f814716b0257cd65e89d10ff653a24d2 603 Gene3D G3DSA:3.40.50.970 3 173 1.0E-49 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS23655 f814716b0257cd65e89d10ff653a24d2 603 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 3 169 1.6E-39 T 06-07-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 BWK49_RS23655 f814716b0257cd65e89d10ff653a24d2 603 Gene3D G3DSA:3.40.50.1220 193 344 7.8E-35 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain BWK49_RS23655 f814716b0257cd65e89d10ff653a24d2 603 SUPERFAMILY SSF52518 3 176 5.27E-43 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS23655 f814716b0257cd65e89d10ff653a24d2 603 SUPERFAMILY SSF52467 189 361 1.48E-37 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain BWK49_RS23655 f814716b0257cd65e89d10ff653a24d2 603 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 388 543 2.7E-28 T 06-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 BWK49_RS04760 c9bd3ef57adda13977caa3d754bde62f 517 SUPERFAMILY SSF56801 3 509 2.35E-154 T 06-07-2017 BWK49_RS04760 c9bd3ef57adda13977caa3d754bde62f 517 Gene3D G3DSA:2.30.38.10 331 403 1.7E-28 T 06-07-2017 BWK49_RS04760 c9bd3ef57adda13977caa3d754bde62f 517 ProSitePatterns PS00455 Putative AMP-binding domain signature. 163 174 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS04760 c9bd3ef57adda13977caa3d754bde62f 517 Pfam PF00501 AMP-binding enzyme 9 412 1.3E-102 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS04760 c9bd3ef57adda13977caa3d754bde62f 517 Pfam PF13193 AMP-binding enzyme C-terminal domain 421 496 7.2E-22 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS04760 c9bd3ef57adda13977caa3d754bde62f 517 Gene3D G3DSA:3.40.50.980 173 323 2.1E-44 T 06-07-2017 BWK49_RS04760 c9bd3ef57adda13977caa3d754bde62f 517 Gene3D G3DSA:3.40.50.980 148 172 1.2E-31 T 06-07-2017 BWK49_RS04760 c9bd3ef57adda13977caa3d754bde62f 517 Gene3D G3DSA:3.40.50.980 3 114 1.2E-31 T 06-07-2017 BWK49_RS04760 c9bd3ef57adda13977caa3d754bde62f 517 Gene3D G3DSA:3.30.300.30 407 506 3.2E-34 T 06-07-2017 BWK49_RS24045 44222a0f43c1ce03be743c6c26b56890 288 Pfam PF00296 Luciferase-like monooxygenase 102 257 7.1E-7 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS24045 44222a0f43c1ce03be743c6c26b56890 288 Pfam PF00296 Luciferase-like monooxygenase 25 115 5.8E-9 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS24045 44222a0f43c1ce03be743c6c26b56890 288 TIGRFAM TIGR03620 F420_MSMEG_4141: probable F420-dependent oxidoreductase, MSMEG_4141 family 11 282 1.1E-113 T 06-07-2017 IPR019922 Luciferase-like, F420-dependent oxidoreductase, MSMEG4141, predicted BWK49_RS24045 44222a0f43c1ce03be743c6c26b56890 288 SUPERFAMILY SSF51679 14 275 2.49E-37 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS24045 44222a0f43c1ce03be743c6c26b56890 288 Gene3D G3DSA:3.20.20.30 14 127 2.2E-10 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS24045 44222a0f43c1ce03be743c6c26b56890 288 Gene3D G3DSA:3.20.20.30 134 278 1.5E-16 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS17750 ba9cf6008222a93bade39e86560324d2 369 Gene3D G3DSA:3.90.25.10 214 351 2.5E-27 T 06-07-2017 BWK49_RS17750 ba9cf6008222a93bade39e86560324d2 369 SUPERFAMILY SSF51735 158 349 5.51E-72 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS17750 ba9cf6008222a93bade39e86560324d2 369 SUPERFAMILY SSF51735 1 127 5.51E-72 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS17750 ba9cf6008222a93bade39e86560324d2 369 Pfam PF01370 NAD dependent epimerase/dehydratase family 1 271 7.7E-43 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 BWK49_RS17750 ba9cf6008222a93bade39e86560324d2 369 Gene3D G3DSA:3.40.50.720 159 213 2.1E-40 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS17750 ba9cf6008222a93bade39e86560324d2 369 Gene3D G3DSA:3.40.50.720 1 127 2.1E-40 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS02285 99862aaa6f38c92c6a7614926f5de559 1127 Gene3D G3DSA:2.40.50.100 1052 1126 4.3E-19 T 06-07-2017 BWK49_RS02285 99862aaa6f38c92c6a7614926f5de559 1127 Gene3D G3DSA:3.30.1490.20 131 201 4.8E-22 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 BWK49_RS02285 99862aaa6f38c92c6a7614926f5de559 1127 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 BWK49_RS02285 99862aaa6f38c92c6a7614926f5de559 1127 Pfam PF00289 Biotin carboxylase, N-terminal domain 3 111 5.3E-39 T 06-07-2017 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 BWK49_RS02285 99862aaa6f38c92c6a7614926f5de559 1127 TIGRFAM TIGR01235 pyruv_carbox: pyruvate carboxylase 4 1126 0.0 T 06-07-2017 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 BWK49_RS02285 99862aaa6f38c92c6a7614926f5de559 1127 Gene3D G3DSA:3.40.50.20 2 130 1.4E-44 T 06-07-2017 IPR016185 Pre-ATP-grasp domain BWK49_RS02285 99862aaa6f38c92c6a7614926f5de559 1127 Pfam PF00682 HMGL-like 524 795 2.6E-28 T 06-07-2017 IPR000891 Pyruvate carboxyltransferase GO:0003824 BWK49_RS02285 99862aaa6f38c92c6a7614926f5de559 1127 Gene3D G3DSA:3.10.600.10 961 1048 2.1E-29 T 06-07-2017 BWK49_RS02285 99862aaa6f38c92c6a7614926f5de559 1127 PIRSF PIRSF001594 1 1127 0.0 T 06-07-2017 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 BWK49_RS02285 99862aaa6f38c92c6a7614926f5de559 1127 Gene3D G3DSA:3.20.20.70 502 811 1.2E-124 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 BWK49_RS02285 99862aaa6f38c92c6a7614926f5de559 1127 SUPERFAMILY SSF56059 84 357 3.89E-67 T 06-07-2017 BWK49_RS02285 99862aaa6f38c92c6a7614926f5de559 1127 SUPERFAMILY SSF51230 1050 1127 1.83E-16 T 06-07-2017 IPR011053 Single hybrid motif BWK49_RS02285 99862aaa6f38c92c6a7614926f5de559 1127 Pfam PF02785 Biotin carboxylase C-terminal domain 339 446 5.6E-36 T 06-07-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 BWK49_RS02285 99862aaa6f38c92c6a7614926f5de559 1127 Gene3D G3DSA:3.30.470.20 205 451 4.0E-99 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 BWK49_RS02285 99862aaa6f38c92c6a7614926f5de559 1127 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 117 323 1.8E-68 T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 BWK49_RS02285 99862aaa6f38c92c6a7614926f5de559 1127 Pfam PF02436 Conserved carboxylase domain 820 1009 3.2E-54 T 06-07-2017 IPR003379 Carboxylase, conserved domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 BWK49_RS02285 99862aaa6f38c92c6a7614926f5de559 1127 SUPERFAMILY SSF52440 2 112 6.33E-40 T 06-07-2017 IPR016185 Pre-ATP-grasp domain BWK49_RS02285 99862aaa6f38c92c6a7614926f5de559 1127 SUPERFAMILY SSF51246 333 451 1.46E-38 T 06-07-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 BWK49_RS02285 99862aaa6f38c92c6a7614926f5de559 1127 SUPERFAMILY SSF51569 517 828 1.74E-75 T 06-07-2017 BWK49_RS02285 99862aaa6f38c92c6a7614926f5de559 1127 SMART SM00878 339 445 2.1E-55 T 06-07-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 BWK49_RS02285 99862aaa6f38c92c6a7614926f5de559 1127 SUPERFAMILY SSF89000 825 993 1.02E-38 T 06-07-2017 BWK49_RS02285 99862aaa6f38c92c6a7614926f5de559 1127 Pfam PF00364 Biotin-requiring enzyme 1068 1126 2.4E-14 T 06-07-2017 IPR000089 Biotin/lipoyl attachment BWK49_RS16940 ea8238f223694c0480d9395d9b2bf4be 476 Gene3D G3DSA:1.10.40.30 381 437 5.3E-28 T 06-07-2017 BWK49_RS16940 ea8238f223694c0480d9395d9b2bf4be 476 Gene3D G3DSA:1.10.275.10 8 112 5.2E-30 T 06-07-2017 IPR024083 Fumarase/histidase, N-terminal BWK49_RS16940 ea8238f223694c0480d9395d9b2bf4be 476 PRINTS PR00149 Fumarate lyase superfamily signature 281 297 1.7E-25 T 06-07-2017 IPR000362 Fumarate lyase family BWK49_RS16940 ea8238f223694c0480d9395d9b2bf4be 476 PRINTS PR00149 Fumarate lyase superfamily signature 237 264 1.7E-25 T 06-07-2017 IPR000362 Fumarate lyase family BWK49_RS16940 ea8238f223694c0480d9395d9b2bf4be 476 PRINTS PR00149 Fumarate lyase superfamily signature 108 126 1.7E-25 T 06-07-2017 IPR000362 Fumarate lyase family BWK49_RS16940 ea8238f223694c0480d9395d9b2bf4be 476 PRINTS PR00149 Fumarate lyase superfamily signature 153 171 1.7E-25 T 06-07-2017 IPR000362 Fumarate lyase family BWK49_RS16940 ea8238f223694c0480d9395d9b2bf4be 476 TIGRFAM TIGR00838 argH: argininosuccinate lyase 8 457 6.4E-184 T 06-07-2017 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 BWK49_RS16940 ea8238f223694c0480d9395d9b2bf4be 476 Gene3D G3DSA:1.20.200.10 113 380 3.4E-95 T 06-07-2017 BWK49_RS16940 ea8238f223694c0480d9395d9b2bf4be 476 ProSitePatterns PS00163 Fumarate lyases signature. 281 290 - T 06-07-2017 IPR020557 Fumarate lyase, conserved site GO:0003824 BWK49_RS16940 ea8238f223694c0480d9395d9b2bf4be 476 Hamap MF_00006 Argininosuccinate lyase [argH]. 7 459 39.099 T 06-07-2017 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 BWK49_RS16940 ea8238f223694c0480d9395d9b2bf4be 476 Pfam PF14698 Argininosuccinate lyase C-terminal 369 437 2.1E-21 T 06-07-2017 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 BWK49_RS16940 ea8238f223694c0480d9395d9b2bf4be 476 PRINTS PR00145 Argininosuccinate lyase family signature 237 261 2.7E-52 T 06-07-2017 BWK49_RS16940 ea8238f223694c0480d9395d9b2bf4be 476 PRINTS PR00145 Argininosuccinate lyase family signature 148 168 2.7E-52 T 06-07-2017 BWK49_RS16940 ea8238f223694c0480d9395d9b2bf4be 476 PRINTS PR00145 Argininosuccinate lyase family signature 107 129 2.7E-52 T 06-07-2017 BWK49_RS16940 ea8238f223694c0480d9395d9b2bf4be 476 PRINTS PR00145 Argininosuccinate lyase family signature 199 215 2.7E-52 T 06-07-2017 BWK49_RS16940 ea8238f223694c0480d9395d9b2bf4be 476 PRINTS PR00145 Argininosuccinate lyase family signature 316 335 2.7E-52 T 06-07-2017 BWK49_RS16940 ea8238f223694c0480d9395d9b2bf4be 476 PRINTS PR00145 Argininosuccinate lyase family signature 281 297 2.7E-52 T 06-07-2017 BWK49_RS16940 ea8238f223694c0480d9395d9b2bf4be 476 SUPERFAMILY SSF48557 11 457 4.71E-130 T 06-07-2017 IPR008948 L-Aspartase-like GO:0003824 BWK49_RS16940 ea8238f223694c0480d9395d9b2bf4be 476 Pfam PF00206 Lyase 16 306 7.6E-60 T 06-07-2017 IPR022761 Fumarate lyase, N-terminal BWK49_RS19800 b8ea17d3b95c76a4b3216cb3bfd43ea2 371 Gene3D G3DSA:3.40.50.1770 203 358 1.9E-23 T 06-07-2017 BWK49_RS19800 b8ea17d3b95c76a4b3216cb3bfd43ea2 371 SMART SM01003 4 137 5.9E-77 T 06-07-2017 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal BWK49_RS19800 b8ea17d3b95c76a4b3216cb3bfd43ea2 371 ProSitePatterns PS00836 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 1. 4 30 - T 06-07-2017 IPR008142 Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 GO:0016491|GO:0055114 Reactome: R-HSA-71403 BWK49_RS19800 b8ea17d3b95c76a4b3216cb3bfd43ea2 371 Gene3D G3DSA:3.40.50.1770 1 169 1.4E-58 T 06-07-2017 BWK49_RS19800 b8ea17d3b95c76a4b3216cb3bfd43ea2 371 Gene3D G3DSA:3.50.50.60 170 202 2.5E-5 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS19800 b8ea17d3b95c76a4b3216cb3bfd43ea2 371 TIGRFAM TIGR00518 alaDH: alanine dehydrogenase 1 370 1.1E-187 T 06-07-2017 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 BWK49_RS19800 b8ea17d3b95c76a4b3216cb3bfd43ea2 371 PIRSF PIRSF000183 1 371 1.1E-170 T 06-07-2017 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 BWK49_RS19800 b8ea17d3b95c76a4b3216cb3bfd43ea2 371 SMART SM01002 149 297 4.6E-78 T 06-07-2017 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain BWK49_RS19800 b8ea17d3b95c76a4b3216cb3bfd43ea2 371 SUPERFAMILY SSF52283 305 360 5.27E-64 T 06-07-2017 BWK49_RS19800 b8ea17d3b95c76a4b3216cb3bfd43ea2 371 SUPERFAMILY SSF52283 1 137 5.27E-64 T 06-07-2017 BWK49_RS19800 b8ea17d3b95c76a4b3216cb3bfd43ea2 371 SUPERFAMILY SSF51735 137 303 4.51E-48 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS19800 b8ea17d3b95c76a4b3216cb3bfd43ea2 371 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 137 3.1E-45 T 06-07-2017 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal BWK49_RS19800 b8ea17d3b95c76a4b3216cb3bfd43ea2 371 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 173 198 - T 06-07-2017 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1|Reactome: R-HSA-71403 BWK49_RS19800 b8ea17d3b95c76a4b3216cb3bfd43ea2 371 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 142 351 1.7E-77 T 06-07-2017 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain BWK49_RS27410 1f38ae395b8ce27fb58ce22f3c688199 366 SUPERFAMILY SSF51735 1 172 4.15E-13 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS27410 1f38ae395b8ce27fb58ce22f3c688199 366 Gene3D G3DSA:3.40.50.720 2 216 1.3E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS06480 10f94d475ec7bc0d22543f8d031b9904 151 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 3 138 2.2E-11 T 06-07-2017 IPR019587 Polyketide cyclase/dehydrase BWK49_RS06480 10f94d475ec7bc0d22543f8d031b9904 151 Gene3D G3DSA:3.30.530.20 6 118 1.3E-10 T 06-07-2017 IPR023393 START-like domain BWK49_RS06480 10f94d475ec7bc0d22543f8d031b9904 151 SUPERFAMILY SSF55961 4 141 6.88E-22 T 06-07-2017 BWK49_RS09955 08d0f1a5e23dc72a989a36ddd5b7ccc3 184 Gene3D G3DSA:1.10.530.10 106 183 8.1E-38 T 06-07-2017 BWK49_RS09955 08d0f1a5e23dc72a989a36ddd5b7ccc3 184 Pfam PF06737 Transglycosylase-like domain 109 180 6.5E-33 T 06-07-2017 IPR010618 Transglycosylase-like BWK49_RS09955 08d0f1a5e23dc72a989a36ddd5b7ccc3 184 SUPERFAMILY SSF53955 107 183 6.68E-31 T 06-07-2017 IPR023346 Lysozyme-like domain BWK49_RS23970 211c68a7ae50ab7b19f8d05270da9860 422 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 110 120 - T 06-07-2017 IPR022398 Peptidase S8, subtilisin, His-active site BWK49_RS23970 211c68a7ae50ab7b19f8d05270da9860 422 Pfam PF00082 Subtilase family 70 342 9.0E-32 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 BWK49_RS23970 211c68a7ae50ab7b19f8d05270da9860 422 Gene3D G3DSA:3.40.50.200 58 351 3.0E-68 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 BWK49_RS23970 211c68a7ae50ab7b19f8d05270da9860 422 TIGRFAM TIGR03921 T7SS_mycosin: type VII secretion-associated serine protease mycosin 60 413 4.8E-121 T 06-07-2017 IPR023834 Type VII secretion system peptidase S8A, mycosin-1 BWK49_RS23970 211c68a7ae50ab7b19f8d05270da9860 422 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 75 85 - T 06-07-2017 IPR023827 Peptidase S8, subtilisin, Asp-active site BWK49_RS23970 211c68a7ae50ab7b19f8d05270da9860 422 SUPERFAMILY SSF52743 55 352 2.49E-61 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 BWK49_RS23970 211c68a7ae50ab7b19f8d05270da9860 422 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 293 303 - T 06-07-2017 IPR023828 Peptidase S8, subtilisin, Ser-active site BWK49_RS23970 211c68a7ae50ab7b19f8d05270da9860 422 PRINTS PR00723 Subtilisin serine protease family (S8) signature 292 308 3.8E-13 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related BWK49_RS23970 211c68a7ae50ab7b19f8d05270da9860 422 PRINTS PR00723 Subtilisin serine protease family (S8) signature 70 89 3.8E-13 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related BWK49_RS23970 211c68a7ae50ab7b19f8d05270da9860 422 PRINTS PR00723 Subtilisin serine protease family (S8) signature 106 119 3.8E-13 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related BWK49_RS21755 b5c4579d8a01a12dd61f201bc7a2a3a6 427 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 197 418 1.4E-33 T 06-07-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 BWK49_RS21755 b5c4579d8a01a12dd61f201bc7a2a3a6 427 SUPERFAMILY SSF55961 174 420 1.65E-35 T 06-07-2017 BWK49_RS21755 b5c4579d8a01a12dd61f201bc7a2a3a6 427 Gene3D G3DSA:3.90.380.10 167 403 3.0E-25 T 06-07-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 BWK49_RS21755 b5c4579d8a01a12dd61f201bc7a2a3a6 427 Pfam PF00355 Rieske [2Fe-2S] domain 49 135 2.2E-11 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS21755 b5c4579d8a01a12dd61f201bc7a2a3a6 427 Gene3D G3DSA:2.102.10.10 48 166 8.6E-29 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS21755 b5c4579d8a01a12dd61f201bc7a2a3a6 427 SUPERFAMILY SSF50022 15 170 9.56E-37 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS21755 b5c4579d8a01a12dd61f201bc7a2a3a6 427 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 87 107 5.9E-6 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS21755 b5c4579d8a01a12dd61f201bc7a2a3a6 427 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 34 59 5.9E-6 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS25405 ea00034cd7c3e5140509fe5a0c266647 372 Gene3D G3DSA:3.30.465.10 244 259 7.4E-48 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 BWK49_RS25405 ea00034cd7c3e5140509fe5a0c266647 372 Gene3D G3DSA:3.30.465.10 91 210 7.4E-48 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 BWK49_RS25405 ea00034cd7c3e5140509fe5a0c266647 372 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 372 74.243 T 06-07-2017 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 BWK49_RS25405 ea00034cd7c3e5140509fe5a0c266647 372 Gene3D G3DSA:3.90.78.10 260 371 5.4E-39 T 06-07-2017 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 BWK49_RS25405 ea00034cd7c3e5140509fe5a0c266647 372 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 233 368 9.4E-35 T 06-07-2017 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 BWK49_RS25405 ea00034cd7c3e5140509fe5a0c266647 372 Gene3D G3DSA:3.30.43.10 19 81 1.7E-10 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 BWK49_RS25405 ea00034cd7c3e5140509fe5a0c266647 372 Pfam PF01565 FAD binding domain 34 167 1.2E-22 T 06-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 BWK49_RS25405 ea00034cd7c3e5140509fe5a0c266647 372 SUPERFAMILY SSF56194 229 370 1.19E-32 T 06-07-2017 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 BWK49_RS25405 ea00034cd7c3e5140509fe5a0c266647 372 SUPERFAMILY SSF56176 20 199 5.72E-35 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 BWK49_RS14500 2c91d1e1619e34219d00e6e11e6eccff 316 Gene3D G3DSA:1.10.10.60 269 314 2.1E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS14500 2c91d1e1619e34219d00e6e11e6eccff 316 Gene3D G3DSA:1.10.10.60 218 268 1.6E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS14500 2c91d1e1619e34219d00e6e11e6eccff 316 SUPERFAMILY SSF52317 2 194 1.9E-47 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like BWK49_RS14500 2c91d1e1619e34219d00e6e11e6eccff 316 Pfam PF01965 DJ-1/PfpI family 4 174 2.7E-24 T 06-07-2017 IPR002818 DJ-1/PfpI BWK49_RS14500 2c91d1e1619e34219d00e6e11e6eccff 316 Pfam PF12833 Helix-turn-helix domain 235 313 1.9E-22 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 BWK49_RS14500 2c91d1e1619e34219d00e6e11e6eccff 316 SUPERFAMILY SSF46689 214 262 1.48E-8 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS14500 2c91d1e1619e34219d00e6e11e6eccff 316 SUPERFAMILY SSF46689 265 315 9.71E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS14500 2c91d1e1619e34219d00e6e11e6eccff 316 Gene3D G3DSA:3.40.50.880 4 217 5.3E-55 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like BWK49_RS14500 2c91d1e1619e34219d00e6e11e6eccff 316 SMART SM00342 229 312 2.1E-27 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 BWK49_RS03100 f554ce5da05ee8ae09fbcf499b30caba 271 Pfam PF03309 Type III pantothenate kinase 2 206 3.7E-56 T 06-07-2017 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 BWK49_RS03100 f554ce5da05ee8ae09fbcf499b30caba 271 Hamap MF_01274 Type III pantothenate kinase [coaX]. 1 260 31.151 T 06-07-2017 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 BWK49_RS03100 f554ce5da05ee8ae09fbcf499b30caba 271 SUPERFAMILY SSF53067 2 124 4.86E-24 T 06-07-2017 BWK49_RS03100 f554ce5da05ee8ae09fbcf499b30caba 271 TIGRFAM TIGR00671 baf: pantothenate kinase, type III 2 256 4.8E-89 T 06-07-2017 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 BWK49_RS03100 f554ce5da05ee8ae09fbcf499b30caba 271 SUPERFAMILY SSF53067 126 259 2.07E-30 T 06-07-2017 BWK49_RS03100 f554ce5da05ee8ae09fbcf499b30caba 271 Gene3D G3DSA:3.30.420.40 96 264 4.0E-48 T 06-07-2017 BWK49_RS08030 5dc839b1d65a674e74ccd6533811df63 240 Gene3D G3DSA:3.40.50.720 5 146 2.3E-26 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS08030 5dc839b1d65a674e74ccd6533811df63 240 SUPERFAMILY SSF116726 134 213 2.49E-11 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 BWK49_RS08030 5dc839b1d65a674e74ccd6533811df63 240 SUPERFAMILY SSF51735 3 146 1.21E-25 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS08030 5dc839b1d65a674e74ccd6533811df63 240 Pfam PF02254 TrkA-N domain 5 118 7.0E-21 T 06-07-2017 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 BWK49_RS08030 5dc839b1d65a674e74ccd6533811df63 240 Pfam PF02080 TrkA-C domain 151 216 2.2E-12 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 BWK49_RS08030 5dc839b1d65a674e74ccd6533811df63 240 Gene3D G3DSA:3.30.70.1450 147 213 5.7E-8 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 BWK49_RS07355 99200eaeb87f385f618e61b775b37d3e 190 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 6 173 4.4E-52 T 06-07-2017 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 BWK49_RS07355 99200eaeb87f385f618e61b775b37d3e 190 Gene3D G3DSA:2.60.120.10 2 175 7.3E-57 T 06-07-2017 IPR014710 RmlC-like jelly roll fold BWK49_RS07355 99200eaeb87f385f618e61b775b37d3e 190 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 1 173 2.0E-81 T 06-07-2017 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 BWK49_RS07355 99200eaeb87f385f618e61b775b37d3e 190 SUPERFAMILY SSF51182 2 175 1.42E-54 T 06-07-2017 IPR011051 RmlC-like cupin domain BWK49_RS05870 f5d99b0a861b16049872771cac135245 217 Pfam PF00072 Response regulator receiver domain 12 123 1.6E-27 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 BWK49_RS05870 f5d99b0a861b16049872771cac135245 217 SUPERFAMILY SSF52172 10 135 2.56E-31 T 06-07-2017 IPR011006 CheY-like superfamily BWK49_RS05870 f5d99b0a861b16049872771cac135245 217 Gene3D G3DSA:1.10.10.10 128 216 5.5E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS05870 f5d99b0a861b16049872771cac135245 217 SMART SM00421 153 210 6.5E-22 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS05870 f5d99b0a861b16049872771cac135245 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 186 198 4.5E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS05870 f5d99b0a861b16049872771cac135245 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 186 4.5E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS05870 f5d99b0a861b16049872771cac135245 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 170 4.5E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS05870 f5d99b0a861b16049872771cac135245 217 Pfam PF00196 Bacterial regulatory proteins, luxR family 155 209 4.4E-16 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS05870 f5d99b0a861b16049872771cac135245 217 SUPERFAMILY SSF46894 145 216 3.2E-19 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 BWK49_RS05870 f5d99b0a861b16049872771cac135245 217 Gene3D G3DSA:3.40.50.2300 9 127 3.9E-34 T 06-07-2017 BWK49_RS05870 f5d99b0a861b16049872771cac135245 217 SMART SM00448 10 123 2.7E-30 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 BWK49_RS01675 59d77ae3cb6bd44e48d21a528ba8e8e4 102 SUPERFAMILY SSF46689 2 91 1.08E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS01675 59d77ae3cb6bd44e48d21a528ba8e8e4 102 Gene3D G3DSA:1.10.10.60 7 88 3.8E-21 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS01675 59d77ae3cb6bd44e48d21a528ba8e8e4 102 Pfam PF01527 Transposase 3 72 4.9E-9 T 06-07-2017 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 BWK49_RS12915 74714af3713d2975189298e39edd857e 643 SUPERFAMILY SSF53098 35 227 8.35E-52 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS12915 74714af3713d2975189298e39edd857e 643 SUPERFAMILY SSF82771 249 327 1.22E-14 T 06-07-2017 IPR000305 GIY-YIG nuclease superfamily BWK49_RS12915 74714af3713d2975189298e39edd857e 643 SMART SM00479 39 216 5.0E-51 T 06-07-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III BWK49_RS12915 74714af3713d2975189298e39edd857e 643 Pfam PF00929 Exonuclease 41 207 1.4E-34 T 06-07-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III BWK49_RS12915 74714af3713d2975189298e39edd857e 643 Gene3D G3DSA:3.30.420.10 34 222 1.1E-55 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS12915 74714af3713d2975189298e39edd857e 643 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 34 217 9.0E-27 T 06-07-2017 IPR006054 DNA polymerase III, epsilon subunit GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 BWK49_RS12915 74714af3713d2975189298e39edd857e 643 SMART SM00465 249 330 7.1E-10 T 06-07-2017 IPR000305 GIY-YIG nuclease superfamily BWK49_RS23820 fa6497f6e229e3bb063874be26e9c340 216 Pfam PF07077 Protein of unknown function (DUF1345) 39 204 2.2E-49 T 06-07-2017 IPR009781 Protein of unknown function DUF1345 BWK49_RS25385 b6f34ec9738d51d793e6b04d1d2bd13d 443 SUPERFAMILY SSF53067 114 408 8.46E-29 T 06-07-2017 BWK49_RS25385 b6f34ec9738d51d793e6b04d1d2bd13d 443 SUPERFAMILY SSF46785 43 108 1.66E-6 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS25385 b6f34ec9738d51d793e6b04d1d2bd13d 443 Gene3D G3DSA:3.30.420.40 113 252 8.5E-25 T 06-07-2017 BWK49_RS25385 b6f34ec9738d51d793e6b04d1d2bd13d 443 Pfam PF00480 ROK family 115 383 2.3E-17 T 06-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 BWK49_RS25385 b6f34ec9738d51d793e6b04d1d2bd13d 443 Gene3D G3DSA:1.10.10.10 43 109 1.0E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS25385 b6f34ec9738d51d793e6b04d1d2bd13d 443 Gene3D G3DSA:3.30.420.40 253 390 1.2E-18 T 06-07-2017 BWK49_RS24320 74d5cd7a86e791b74394b53d50342877 223 Gene3D G3DSA:3.40.1370.10 65 209 3.3E-50 T 06-07-2017 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 BWK49_RS24320 74d5cd7a86e791b74394b53d50342877 223 SUPERFAMILY SSF52166 10 209 2.49E-71 T 06-07-2017 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 BWK49_RS24320 74d5cd7a86e791b74394b53d50342877 223 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 24 209 1.3E-68 T 06-07-2017 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS24320 74d5cd7a86e791b74394b53d50342877 223 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 16 215 32.179 T 06-07-2017 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS24320 74d5cd7a86e791b74394b53d50342877 223 Pfam PF00573 Ribosomal protein L4/L1 family 24 208 6.3E-64 T 06-07-2017 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 BWK49_RS06370 dd244f20f9841d2747c00fa28ff1cc5e 579 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 9 296 3.7E-67 T 06-07-2017 IPR005693 Virulence factor Mce protein BWK49_RS06370 dd244f20f9841d2747c00fa28ff1cc5e 579 Pfam PF02470 MlaD protein 41 113 2.3E-12 T 06-07-2017 IPR003399 Mce/MlaD BWK49_RS13760 3945006c49dc3c266b68699d8751cdd3 323 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 12 167 2.0E-18 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS13760 3945006c49dc3c266b68699d8751cdd3 323 SUPERFAMILY SSF54427 179 295 2.48E-8 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS13760 3945006c49dc3c266b68699d8751cdd3 323 SUPERFAMILY SSF88946 6 91 1.37E-14 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS13760 3945006c49dc3c266b68699d8751cdd3 323 Gene3D G3DSA:3.10.450.50 179 242 8.7E-7 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS13760 3945006c49dc3c266b68699d8751cdd3 323 SUPERFAMILY SSF88659 106 167 4.49E-10 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS13760 3945006c49dc3c266b68699d8751cdd3 323 Pfam PF08281 Sigma-70, region 4 114 165 6.7E-10 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS13760 3945006c49dc3c266b68699d8751cdd3 323 Gene3D G3DSA:1.10.10.10 107 167 6.1E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS13760 3945006c49dc3c266b68699d8751cdd3 323 Pfam PF04542 Sigma-70 region 2 18 79 3.4E-11 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS13760 3945006c49dc3c266b68699d8751cdd3 323 Gene3D G3DSA:1.10.1740.10 6 98 1.2E-15 T 06-07-2017 BWK49_RS09530 bc66f24207d8db94c68583416f46f5b9 273 Gene3D G3DSA:1.10.10.10 11 84 2.0E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS09530 bc66f24207d8db94c68583416f46f5b9 273 Pfam PF00392 Bacterial regulatory proteins, gntR family 21 78 1.1E-16 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 BWK49_RS09530 bc66f24207d8db94c68583416f46f5b9 273 Gene3D G3DSA:1.20.120.530 106 249 4.6E-15 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal BWK49_RS09530 bc66f24207d8db94c68583416f46f5b9 273 SMART SM00418 18 101 0.007 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 BWK49_RS09530 bc66f24207d8db94c68583416f46f5b9 273 Pfam PF07729 FCD domain 113 241 5.2E-19 T 06-07-2017 IPR011711 GntR, C-terminal BWK49_RS09530 bc66f24207d8db94c68583416f46f5b9 273 SMART SM00895 109 242 1.7E-15 T 06-07-2017 IPR011711 GntR, C-terminal BWK49_RS09530 bc66f24207d8db94c68583416f46f5b9 273 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 56 7.5E-5 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 BWK49_RS09530 bc66f24207d8db94c68583416f46f5b9 273 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 56 72 7.5E-5 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 BWK49_RS09530 bc66f24207d8db94c68583416f46f5b9 273 SMART SM00345 23 84 2.6E-13 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 BWK49_RS09530 bc66f24207d8db94c68583416f46f5b9 273 SUPERFAMILY SSF48008 106 248 2.38E-16 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal BWK49_RS09530 bc66f24207d8db94c68583416f46f5b9 273 SUPERFAMILY SSF46785 15 88 1.03E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS17140 c00a75e2cc341d792337926db7b8bb3e 332 ProSitePatterns PS00333 ATP-dependent DNA ligase signature 2. 188 211 - T 06-07-2017 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 BWK49_RS17140 c00a75e2cc341d792337926db7b8bb3e 332 Pfam PF01068 ATP dependent DNA ligase domain 35 211 6.5E-31 T 06-07-2017 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 BWK49_RS17140 c00a75e2cc341d792337926db7b8bb3e 332 ProSitePatterns PS00697 ATP-dependent DNA ligase AMP-binding site. 44 52 - T 06-07-2017 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 BWK49_RS17140 c00a75e2cc341d792337926db7b8bb3e 332 Gene3D G3DSA:3.30.1490.70 20 48 1.7E-19 T 06-07-2017 BWK49_RS17140 c00a75e2cc341d792337926db7b8bb3e 332 Gene3D G3DSA:3.30.1490.70 169 212 1.7E-19 T 06-07-2017 BWK49_RS17140 c00a75e2cc341d792337926db7b8bb3e 332 SUPERFAMILY SSF56091 17 212 1.01E-45 T 06-07-2017 BWK49_RS17140 c00a75e2cc341d792337926db7b8bb3e 332 Gene3D G3DSA:3.30.470.30 49 160 7.3E-27 T 06-07-2017 BWK49_RS17140 c00a75e2cc341d792337926db7b8bb3e 332 TIGRFAM TIGR02779 NHEJ_ligase_lig: DNA ligase D, ligase domain 26 328 1.2E-86 T 06-07-2017 IPR014146 DNA ligase D, ligase domain BWK49_RS17140 c00a75e2cc341d792337926db7b8bb3e 332 Pfam PF04679 ATP dependent DNA ligase C terminal region 232 322 5.5E-27 T 06-07-2017 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 BWK49_RS17140 c00a75e2cc341d792337926db7b8bb3e 332 Gene3D G3DSA:2.40.50.140 214 330 1.1E-44 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS17140 c00a75e2cc341d792337926db7b8bb3e 332 SUPERFAMILY SSF50249 214 330 3.6E-31 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS00250 f44ce6fc44b46241663ca2e8aee2faa2 201 Gene3D G3DSA:3.40.1740.10 15 56 1.3E-23 T 06-07-2017 BWK49_RS00250 f44ce6fc44b46241663ca2e8aee2faa2 201 Gene3D G3DSA:3.40.1740.10 142 185 1.3E-23 T 06-07-2017 BWK49_RS00250 f44ce6fc44b46241663ca2e8aee2faa2 201 SUPERFAMILY SSF143456 15 195 1.44E-45 T 06-07-2017 BWK49_RS00250 f44ce6fc44b46241663ca2e8aee2faa2 201 Pfam PF02622 Uncharacterized ACR, COG1678 30 184 1.9E-35 T 06-07-2017 IPR003774 Protein of unknown function UPF0301 BWK49_RS00250 f44ce6fc44b46241663ca2e8aee2faa2 201 Hamap MF_00758 UPF0301 protein YqgE [yqgE]. 17 198 25.816 T 06-07-2017 IPR003774 Protein of unknown function UPF0301 BWK49_RS21770 41923dce0d02b4048c43faf0fe648c14 1041 SUPERFAMILY SSF56112 25 289 2.83E-60 T 06-07-2017 IPR011009 Protein kinase-like domain BWK49_RS21770 41923dce0d02b4048c43faf0fe648c14 1041 SUPERFAMILY SSF50965 466 545 7.98E-7 T 06-07-2017 IPR011043 Galactose oxidase/kelch, beta-propeller BWK49_RS21770 41923dce0d02b4048c43faf0fe648c14 1041 SUPERFAMILY SSF117281 556 739 3.53E-40 T 06-07-2017 BWK49_RS21770 41923dce0d02b4048c43faf0fe648c14 1041 SMART SM00612 781 827 1.0E-7 T 06-07-2017 IPR006652 Kelch repeat type 1 GO:0005515 BWK49_RS21770 41923dce0d02b4048c43faf0fe648c14 1041 SMART SM00612 631 677 4.9E-9 T 06-07-2017 IPR006652 Kelch repeat type 1 GO:0005515 BWK49_RS21770 41923dce0d02b4048c43faf0fe648c14 1041 SMART SM00612 488 535 14.0 T 06-07-2017 IPR006652 Kelch repeat type 1 GO:0005515 BWK49_RS21770 41923dce0d02b4048c43faf0fe648c14 1041 SMART SM00612 678 724 2.0E-5 T 06-07-2017 IPR006652 Kelch repeat type 1 GO:0005515 BWK49_RS21770 41923dce0d02b4048c43faf0fe648c14 1041 SMART SM00612 725 780 2.6 T 06-07-2017 IPR006652 Kelch repeat type 1 GO:0005515 BWK49_RS21770 41923dce0d02b4048c43faf0fe648c14 1041 SMART SM00612 875 919 0.0092 T 06-07-2017 IPR006652 Kelch repeat type 1 GO:0005515 BWK49_RS21770 41923dce0d02b4048c43faf0fe648c14 1041 SMART SM00612 920 968 2.5E-5 T 06-07-2017 IPR006652 Kelch repeat type 1 GO:0005515 BWK49_RS21770 41923dce0d02b4048c43faf0fe648c14 1041 SMART SM00612 538 584 3.4 T 06-07-2017 IPR006652 Kelch repeat type 1 GO:0005515 BWK49_RS21770 41923dce0d02b4048c43faf0fe648c14 1041 SMART SM00612 969 1015 1.9E-5 T 06-07-2017 IPR006652 Kelch repeat type 1 GO:0005515 BWK49_RS21770 41923dce0d02b4048c43faf0fe648c14 1041 SMART SM00612 585 630 0.092 T 06-07-2017 IPR006652 Kelch repeat type 1 GO:0005515 BWK49_RS21770 41923dce0d02b4048c43faf0fe648c14 1041 SMART SM00612 828 874 0.072 T 06-07-2017 IPR006652 Kelch repeat type 1 GO:0005515 BWK49_RS21770 41923dce0d02b4048c43faf0fe648c14 1041 Gene3D G3DSA:2.130.10.80 466 685 6.5E-39 T 06-07-2017 IPR015916 Galactose oxidase, beta-propeller BWK49_RS21770 41923dce0d02b4048c43faf0fe648c14 1041 Gene3D G3DSA:2.130.10.80 691 893 1.8E-37 T 06-07-2017 IPR015916 Galactose oxidase, beta-propeller BWK49_RS21770 41923dce0d02b4048c43faf0fe648c14 1041 Gene3D G3DSA:2.130.10.80 894 1039 3.4E-32 T 06-07-2017 IPR015916 Galactose oxidase, beta-propeller BWK49_RS21770 41923dce0d02b4048c43faf0fe648c14 1041 Pfam PF01344 Kelch motif 573 614 9.9E-5 T 06-07-2017 IPR006652 Kelch repeat type 1 GO:0005515 BWK49_RS21770 41923dce0d02b4048c43faf0fe648c14 1041 Pfam PF01344 Kelch motif 957 1002 7.0E-8 T 06-07-2017 IPR006652 Kelch repeat type 1 GO:0005515 BWK49_RS21770 41923dce0d02b4048c43faf0fe648c14 1041 Pfam PF01344 Kelch motif 776 814 2.5E-9 T 06-07-2017 IPR006652 Kelch repeat type 1 GO:0005515 BWK49_RS21770 41923dce0d02b4048c43faf0fe648c14 1041 Pfam PF01344 Kelch motif 620 664 2.9E-6 T 06-07-2017 IPR006652 Kelch repeat type 1 GO:0005515 BWK49_RS21770 41923dce0d02b4048c43faf0fe648c14 1041 Pfam PF01344 Kelch motif 666 711 1.9E-7 T 06-07-2017 IPR006652 Kelch repeat type 1 GO:0005515 BWK49_RS21770 41923dce0d02b4048c43faf0fe648c14 1041 Pfam PF01344 Kelch motif 908 955 3.9E-6 T 06-07-2017 IPR006652 Kelch repeat type 1 GO:0005515 BWK49_RS21770 41923dce0d02b4048c43faf0fe648c14 1041 Pfam PF01344 Kelch motif 863 906 1.1E-5 T 06-07-2017 IPR006652 Kelch repeat type 1 GO:0005515 BWK49_RS21770 41923dce0d02b4048c43faf0fe648c14 1041 SMART SM00220 26 286 2.7E-42 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 BWK49_RS21770 41923dce0d02b4048c43faf0fe648c14 1041 Gene3D G3DSA:3.30.200.20 29 93 5.3E-15 T 06-07-2017 BWK49_RS21770 41923dce0d02b4048c43faf0fe648c14 1041 SUPERFAMILY SSF50965 759 1024 1.15E-48 T 06-07-2017 IPR011043 Galactose oxidase/kelch, beta-propeller BWK49_RS21770 41923dce0d02b4048c43faf0fe648c14 1041 Gene3D G3DSA:1.10.510.10 94 275 1.1E-40 T 06-07-2017 BWK49_RS21770 41923dce0d02b4048c43faf0fe648c14 1041 Pfam PF00069 Protein kinase domain 28 273 1.2E-39 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 BWK49_RS18855 d6ae415fd8074f6ae0f93af2f1b24cef 171 ProDom PD339375 PRECURSOR SIGNAL SCO3656 SCO2458 CGL2705 MB2629 RV2598/MT2673.1 58 168 5.0E-43 T 06-07-2017 IPR024486 Protein of unknown function DUF2617 BWK49_RS18855 d6ae415fd8074f6ae0f93af2f1b24cef 171 Pfam PF10936 Protein of unknown function DUF2617 3 169 1.3E-50 T 06-07-2017 IPR024486 Protein of unknown function DUF2617 BWK49_RS19050 e4b34a628de84aa7213ec7843f492284 271 Gene3D G3DSA:1.10.10.10 25 96 1.4E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS19050 e4b34a628de84aa7213ec7843f492284 271 Pfam PF09339 IclR helix-turn-helix domain 29 79 3.8E-13 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 BWK49_RS19050 e4b34a628de84aa7213ec7843f492284 271 SMART SM00346 27 116 1.2E-10 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 BWK49_RS19050 e4b34a628de84aa7213ec7843f492284 271 SUPERFAMILY SSF55781 99 271 1.24E-47 T 06-07-2017 IPR029016 GAF domain-like BWK49_RS19050 e4b34a628de84aa7213ec7843f492284 271 SUPERFAMILY SSF46785 27 98 3.59E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS19050 e4b34a628de84aa7213ec7843f492284 271 Gene3D G3DSA:3.30.450.40 100 271 1.4E-54 T 06-07-2017 IPR029016 GAF domain-like BWK49_RS19050 e4b34a628de84aa7213ec7843f492284 271 Pfam PF01614 Bacterial transcriptional regulator 144 266 6.3E-29 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal BWK49_RS18405 2b307ec6a3e45deb15faad1aec5ba2e1 256 Pfam PF07947 YhhN-like protein 48 235 3.5E-45 T 06-07-2017 IPR012506 YhhN-like GO:0016021 BWK49_RS17610 89e57b78c0b627ee7ef2e56f23164d57 3424 Gene3D G3DSA:3.40.50.980 605 758 1.2E-35 T 06-07-2017 BWK49_RS17610 89e57b78c0b627ee7ef2e56f23164d57 3424 Gene3D G3DSA:3.40.50.980 2103 2266 1.4E-40 T 06-07-2017 BWK49_RS17610 89e57b78c0b627ee7ef2e56f23164d57 3424 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2483 2498 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site BWK49_RS17610 89e57b78c0b627ee7ef2e56f23164d57 3424 SUPERFAMILY SSF52777 1681 1922 1.11E-53 T 06-07-2017 BWK49_RS17610 89e57b78c0b627ee7ef2e56f23164d57 3424 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 2843 3000 2.4E-35 T 06-07-2017 IPR010060 Non-ribosomal peptide synthase BWK49_RS17610 89e57b78c0b627ee7ef2e56f23164d57 3424 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 1342 1498 2.6E-36 T 06-07-2017 IPR010060 Non-ribosomal peptide synthase BWK49_RS17610 89e57b78c0b627ee7ef2e56f23164d57 3424 Pfam PF00668 Condensation domain 1049 1324 2.5E-23 T 06-07-2017 IPR001242 Condensation domain BWK49_RS17610 89e57b78c0b627ee7ef2e56f23164d57 3424 Pfam PF00668 Condensation domain 7 298 7.5E-27 T 06-07-2017 IPR001242 Condensation domain BWK49_RS17610 89e57b78c0b627ee7ef2e56f23164d57 3424 Pfam PF00668 Condensation domain 3007 3298 1.1E-48 T 06-07-2017 IPR001242 Condensation domain BWK49_RS17610 89e57b78c0b627ee7ef2e56f23164d57 3424 Pfam PF00668 Condensation domain 1505 1792 1.9E-56 T 06-07-2017 IPR001242 Condensation domain BWK49_RS17610 89e57b78c0b627ee7ef2e56f23164d57 3424 Pfam PF00668 Condensation domain 2549 2828 3.4E-24 T 06-07-2017 IPR001242 Condensation domain BWK49_RS17610 89e57b78c0b627ee7ef2e56f23164d57 3424 ProSitePatterns PS00455 Putative AMP-binding domain signature. 600 611 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS17610 89e57b78c0b627ee7ef2e56f23164d57 3424 SUPERFAMILY SSF47336 2451 2521 9.03E-17 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS17610 89e57b78c0b627ee7ef2e56f23164d57 3424 SUPERFAMILY SSF52777 1214 1475 3.78E-23 T 06-07-2017 BWK49_RS17610 89e57b78c0b627ee7ef2e56f23164d57 3424 SUPERFAMILY SSF56801 417 963 1.44E-149 T 06-07-2017 BWK49_RS17610 89e57b78c0b627ee7ef2e56f23164d57 3424 SUPERFAMILY SSF52777 189 422 7.67E-25 T 06-07-2017 BWK49_RS17610 89e57b78c0b627ee7ef2e56f23164d57 3424 Gene3D G3DSA:3.40.50.980 456 604 4.0E-47 T 06-07-2017 BWK49_RS17610 89e57b78c0b627ee7ef2e56f23164d57 3424 Pfam PF13193 AMP-binding enzyme C-terminal domain 855 926 2.4E-11 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS17610 89e57b78c0b627ee7ef2e56f23164d57 3424 Pfam PF13193 AMP-binding enzyme C-terminal domain 2363 2434 4.5E-11 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS17610 89e57b78c0b627ee7ef2e56f23164d57 3424 Gene3D G3DSA:3.40.50.980 1949 2102 4.7E-46 T 06-07-2017 BWK49_RS17610 89e57b78c0b627ee7ef2e56f23164d57 3424 SUPERFAMILY SSF52777 10 183 6.11E-29 T 06-07-2017 BWK49_RS17610 89e57b78c0b627ee7ef2e56f23164d57 3424 Gene3D G3DSA:2.30.38.10 2267 2345 1.8E-21 T 06-07-2017 BWK49_RS17610 89e57b78c0b627ee7ef2e56f23164d57 3424 Gene3D G3DSA:2.30.38.10 759 837 2.2E-24 T 06-07-2017 BWK49_RS17610 89e57b78c0b627ee7ef2e56f23164d57 3424 Gene3D G3DSA:1.10.1200.10 2464 2523 2.7E-24 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS17610 89e57b78c0b627ee7ef2e56f23164d57 3424 Gene3D G3DSA:1.10.1200.10 954 1013 2.3E-24 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS17610 89e57b78c0b627ee7ef2e56f23164d57 3424 SUPERFAMILY SSF47336 942 1012 3.14E-16 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS17610 89e57b78c0b627ee7ef2e56f23164d57 3424 SUPERFAMILY SSF52777 2536 2702 3.11E-26 T 06-07-2017 BWK49_RS17610 89e57b78c0b627ee7ef2e56f23164d57 3424 SUPERFAMILY SSF52777 3005 3200 9.67E-40 T 06-07-2017 BWK49_RS17610 89e57b78c0b627ee7ef2e56f23164d57 3424 SUPERFAMILY SSF52777 2728 2976 2.89E-23 T 06-07-2017 BWK49_RS17610 89e57b78c0b627ee7ef2e56f23164d57 3424 SUPERFAMILY SSF56801 1911 2472 2.22E-148 T 06-07-2017 BWK49_RS17610 89e57b78c0b627ee7ef2e56f23164d57 3424 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1976 2379 2.4E-132 T 06-07-2017 IPR010071 Amino acid adenylation domain BWK49_RS17610 89e57b78c0b627ee7ef2e56f23164d57 3424 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 482 871 1.2E-128 T 06-07-2017 IPR010071 Amino acid adenylation domain BWK49_RS17610 89e57b78c0b627ee7ef2e56f23164d57 3424 Pfam PF00550 Phosphopantetheine attachment site 953 1012 3.4E-9 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS17610 89e57b78c0b627ee7ef2e56f23164d57 3424 Pfam PF00550 Phosphopantetheine attachment site 2462 2521 1.0E-10 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS17610 89e57b78c0b627ee7ef2e56f23164d57 3424 SUPERFAMILY SSF52777 1028 1220 3.0E-23 T 06-07-2017 BWK49_RS17610 89e57b78c0b627ee7ef2e56f23164d57 3424 ProSitePatterns PS00012 Phosphopantetheine attachment site. 974 989 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site BWK49_RS17610 89e57b78c0b627ee7ef2e56f23164d57 3424 SMART SM00823 Phosphopantetheine attachment site 950 1018 0.088 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS17610 89e57b78c0b627ee7ef2e56f23164d57 3424 SMART SM00823 Phosphopantetheine attachment site 2459 2527 0.041 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS17610 89e57b78c0b627ee7ef2e56f23164d57 3424 Pfam PF00501 AMP-binding enzyme 461 847 2.4E-89 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS17610 89e57b78c0b627ee7ef2e56f23164d57 3424 Pfam PF00501 AMP-binding enzyme 1957 2355 2.6E-89 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS17610 89e57b78c0b627ee7ef2e56f23164d57 3424 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2094 2105 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS17610 89e57b78c0b627ee7ef2e56f23164d57 3424 Gene3D G3DSA:3.30.300.30 842 953 8.8E-39 T 06-07-2017 BWK49_RS17610 89e57b78c0b627ee7ef2e56f23164d57 3424 Gene3D G3DSA:3.30.300.30 2350 2463 2.2E-39 T 06-07-2017 BWK49_RS17610 89e57b78c0b627ee7ef2e56f23164d57 3424 SUPERFAMILY SSF52777 1502 1696 3.34E-42 T 06-07-2017 BWK49_RS17610 89e57b78c0b627ee7ef2e56f23164d57 3424 SUPERFAMILY SSF52777 3185 3420 4.78E-54 T 06-07-2017 BWK49_RS06240 f40bc462e32fd03b287af014e001132a 474 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 272 283 - T 06-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 BWK49_RS06240 f40bc462e32fd03b287af014e001132a 474 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 244 251 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 BWK49_RS06240 f40bc462e32fd03b287af014e001132a 474 Pfam PF00171 Aldehyde dehydrogenase family 17 470 2.5E-157 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 BWK49_RS06240 f40bc462e32fd03b287af014e001132a 474 SUPERFAMILY SSF53720 3 473 2.36E-155 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 BWK49_RS06240 f40bc462e32fd03b287af014e001132a 474 Gene3D G3DSA:3.40.309.10 259 434 5.2E-60 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 BWK49_RS06240 f40bc462e32fd03b287af014e001132a 474 Gene3D G3DSA:3.40.605.10 4 258 2.3E-90 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 BWK49_RS17190 7695fa729f3132c57e32961f83c2ee16 400 SUPERFAMILY SSF53901 7 230 2.53E-39 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS17190 7695fa729f3132c57e32961f83c2ee16 400 PIRSF PIRSF000429 1 400 2.8E-37 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 BWK49_RS17190 7695fa729f3132c57e32961f83c2ee16 400 Gene3D G3DSA:3.40.47.10 20 114 4.5E-25 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS17190 7695fa729f3132c57e32961f83c2ee16 400 Gene3D G3DSA:3.40.47.10 195 222 4.5E-25 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS17190 7695fa729f3132c57e32961f83c2ee16 400 Gene3D G3DSA:3.40.47.10 144 184 1.0E-7 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS17190 7695fa729f3132c57e32961f83c2ee16 400 Gene3D G3DSA:3.40.47.10 260 398 1.0E-7 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS17190 7695fa729f3132c57e32961f83c2ee16 400 SUPERFAMILY SSF53901 281 389 2.03E-19 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS17190 7695fa729f3132c57e32961f83c2ee16 400 Pfam PF00108 Thiolase, N-terminal domain 24 223 3.8E-9 T 06-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 BWK49_RS24490 b6421c5de90996c4a1b828be00aa2608 1177 Gene3D G3DSA:2.40.50.100 643 713 4.8E-28 T 06-07-2017 BWK49_RS24490 b6421c5de90996c4a1b828be00aa2608 1177 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 32 1139 12.264 T 06-07-2017 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 BWK49_RS24490 b6421c5de90996c4a1b828be00aa2608 1177 Gene3D G3DSA:2.40.50.150 749 880 5.2E-57 T 06-07-2017 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 BWK49_RS24490 b6421c5de90996c4a1b828be00aa2608 1177 Gene3D G3DSA:3.90.1100.10 587 641 1.5E-145 T 06-07-2017 BWK49_RS24490 b6421c5de90996c4a1b828be00aa2608 1177 Gene3D G3DSA:3.90.1100.10 370 518 1.5E-145 T 06-07-2017 BWK49_RS24490 b6421c5de90996c4a1b828be00aa2608 1177 Gene3D G3DSA:3.90.1100.10 39 178 1.5E-145 T 06-07-2017 BWK49_RS24490 b6421c5de90996c4a1b828be00aa2608 1177 Gene3D G3DSA:2.40.270.10 714 741 4.9E-76 T 06-07-2017 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 BWK49_RS24490 b6421c5de90996c4a1b828be00aa2608 1177 Gene3D G3DSA:2.40.270.10 881 1039 4.9E-76 T 06-07-2017 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 BWK49_RS24490 b6421c5de90996c4a1b828be00aa2608 1177 Gene3D G3DSA:3.90.1110.10 180 348 2.3E-64 T 06-07-2017 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 BWK49_RS24490 b6421c5de90996c4a1b828be00aa2608 1177 Pfam PF04561 RNA polymerase Rpb2, domain 2 178 349 7.0E-22 T 06-07-2017 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 BWK49_RS24490 b6421c5de90996c4a1b828be00aa2608 1177 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 246 858 0.0 T 06-07-2017 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 BWK49_RS24490 b6421c5de90996c4a1b828be00aa2608 1177 Pfam PF10385 RNA polymerase beta subunit external 1 domain 518 584 7.8E-27 T 06-07-2017 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 BWK49_RS24490 b6421c5de90996c4a1b828be00aa2608 1177 Pfam PF04560 RNA polymerase Rpb2, domain 7 1063 1137 6.1E-26 T 06-07-2017 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 BWK49_RS24490 b6421c5de90996c4a1b828be00aa2608 1177 Pfam PF00562 RNA polymerase Rpb2, domain 6 645 1061 1.2E-159 T 06-07-2017 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 BWK49_RS24490 b6421c5de90996c4a1b828be00aa2608 1177 ProSitePatterns PS01166 RNA polymerases beta chain signature. 884 896 - T 06-07-2017 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 BWK49_RS24490 b6421c5de90996c4a1b828be00aa2608 1177 Pfam PF04565 RNA polymerase Rpb2, domain 3 440 508 7.1E-29 T 06-07-2017 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 BWK49_RS24490 b6421c5de90996c4a1b828be00aa2608 1177 SUPERFAMILY SSF64484 31 1147 0.0 T 06-07-2017 BWK49_RS24490 b6421c5de90996c4a1b828be00aa2608 1177 Pfam PF04563 RNA polymerase beta subunit 102 425 1.9E-21 T 06-07-2017 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 BWK49_RS24490 b6421c5de90996c4a1b828be00aa2608 1177 Gene3D G3DSA:2.30.150.10 519 584 1.3E-29 T 06-07-2017 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 BWK49_RS28005 d74b2c5487ea8517e5553a7bbbcc68e2 218 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 65 1.2E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS28005 d74b2c5487ea8517e5553a7bbbcc68e2 218 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 1.3E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS28005 d74b2c5487ea8517e5553a7bbbcc68e2 218 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 1.3E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS28005 d74b2c5487ea8517e5553a7bbbcc68e2 218 Gene3D G3DSA:1.10.10.60 6 70 1.7E-23 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS28005 d74b2c5487ea8517e5553a7bbbcc68e2 218 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 85 216 3.5E-16 T 06-07-2017 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 BWK49_RS28005 d74b2c5487ea8517e5553a7bbbcc68e2 218 Gene3D G3DSA:1.10.357.10 71 217 4.2E-34 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS28005 d74b2c5487ea8517e5553a7bbbcc68e2 218 PRINTS PR00400 Tetracycline repressor protein signature 199 213 6.8E-8 T 06-07-2017 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 BWK49_RS28005 d74b2c5487ea8517e5553a7bbbcc68e2 218 PRINTS PR00400 Tetracycline repressor protein signature 32 55 6.8E-8 T 06-07-2017 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 BWK49_RS28005 d74b2c5487ea8517e5553a7bbbcc68e2 218 PRINTS PR00400 Tetracycline repressor protein signature 142 161 6.8E-8 T 06-07-2017 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 BWK49_RS28005 d74b2c5487ea8517e5553a7bbbcc68e2 218 SUPERFAMILY SSF46689 9 74 3.15E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS28005 d74b2c5487ea8517e5553a7bbbcc68e2 218 SUPERFAMILY SSF48498 85 217 5.45E-26 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS00375 78d9c2f6267c84773902f74ad54e090b 96 Gene3D G3DSA:3.30.70.60 1 95 4.6E-34 T 06-07-2017 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 BWK49_RS00375 78d9c2f6267c84773902f74ad54e090b 96 SUPERFAMILY SSF54995 1 95 3.4E-32 T 06-07-2017 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS00375 78d9c2f6267c84773902f74ad54e090b 96 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 95 21.723 T 06-07-2017 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 BWK49_RS00375 78d9c2f6267c84773902f74ad54e090b 96 Pfam PF01250 Ribosomal protein S6 4 92 1.3E-27 T 06-07-2017 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS00375 78d9c2f6267c84773902f74ad54e090b 96 ProSitePatterns PS01048 Ribosomal protein S6 signature. 44 53 - T 06-07-2017 IPR020815 Ribosomal protein S6, conserved site GO:0003735|GO:0005840|GO:0006412|GO:0019843 BWK49_RS00375 78d9c2f6267c84773902f74ad54e090b 96 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 94 1.1E-25 T 06-07-2017 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS26635 6afa4f56e8509052a4ed121ea936ba5e 122 Gene3D G3DSA:2.102.10.10 9 116 4.6E-37 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS26635 6afa4f56e8509052a4ed121ea936ba5e 122 Pfam PF13806 Rieske-like [2Fe-2S] domain 10 113 1.7E-34 T 06-07-2017 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 BWK49_RS26635 6afa4f56e8509052a4ed121ea936ba5e 122 TIGRFAM TIGR02378 nirD_assim_sml: nitrite reductase [NAD(P)H], small subunit 10 114 4.4E-28 T 06-07-2017 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 BWK49_RS26635 6afa4f56e8509052a4ed121ea936ba5e 122 SUPERFAMILY SSF50022 10 117 3.67E-32 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS06710 c419dec3782d988a6154235eed010531 522 SUPERFAMILY SSF51905 1 311 4.41E-27 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS06710 c419dec3782d988a6154235eed010531 522 Gene3D G3DSA:3.50.50.60 1 52 1.9E-10 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS06710 c419dec3782d988a6154235eed010531 522 Gene3D G3DSA:3.50.50.60 482 516 2.4E-13 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS06710 c419dec3782d988a6154235eed010531 522 Gene3D G3DSA:3.50.50.60 216 307 2.4E-13 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS06710 c419dec3782d988a6154235eed010531 522 Pfam PF13450 NAD(P)-binding Rossmann-like domain 6 48 3.4E-8 T 06-07-2017 BWK49_RS15605 4fafd8137348ca8f46eff135e65744a1 422 SUPERFAMILY SSF51556 108 408 1.84E-64 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS15605 4fafd8137348ca8f46eff135e65744a1 422 SUPERFAMILY SSF51556 37 66 1.84E-64 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS15605 4fafd8137348ca8f46eff135e65744a1 422 Pfam PF04909 Amidohydrolase 92 408 3.3E-28 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 BWK49_RS15605 4fafd8137348ca8f46eff135e65744a1 422 Gene3D G3DSA:3.20.20.140 39 409 1.3E-58 T 06-07-2017 BWK49_RS08585 445d86805c5f4f65b7dfce527c7148db 279 SUPERFAMILY SSF161098 6 279 1.87E-70 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS08585 445d86805c5f4f65b7dfce527c7148db 279 Gene3D G3DSA:1.10.3720.10 5 266 8.5E-61 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS08585 445d86805c5f4f65b7dfce527c7148db 279 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 86 271 1.2E-22 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS03405 a19ef6cf544e826a470109d9703748d2 432 Pfam PF00067 Cytochrome P450 304 391 5.6E-14 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS03405 a19ef6cf544e826a470109d9703748d2 432 Gene3D G3DSA:1.10.630.10 13 424 1.4E-108 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS03405 a19ef6cf544e826a470109d9703748d2 432 PRINTS PR00359 B-class P450 signature 221 243 1.0E-45 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS03405 a19ef6cf544e826a470109d9703748d2 432 PRINTS PR00359 B-class P450 signature 181 196 1.0E-45 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS03405 a19ef6cf544e826a470109d9703748d2 432 PRINTS PR00359 B-class P450 signature 164 180 1.0E-45 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS03405 a19ef6cf544e826a470109d9703748d2 432 PRINTS PR00359 B-class P450 signature 376 387 1.0E-45 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS03405 a19ef6cf544e826a470109d9703748d2 432 PRINTS PR00359 B-class P450 signature 345 360 1.0E-45 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS03405 a19ef6cf544e826a470109d9703748d2 432 PRINTS PR00359 B-class P450 signature 300 311 1.0E-45 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS03405 a19ef6cf544e826a470109d9703748d2 432 PRINTS PR00359 B-class P450 signature 118 129 1.0E-45 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS03405 a19ef6cf544e826a470109d9703748d2 432 PRINTS PR00359 B-class P450 signature 317 344 1.0E-45 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS03405 a19ef6cf544e826a470109d9703748d2 432 PRINTS PR00359 B-class P450 signature 367 376 1.0E-45 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS03405 a19ef6cf544e826a470109d9703748d2 432 SUPERFAMILY SSF48264 17 423 3.8E-81 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS22030 8c58a58549a49134fa188c21d2a45a3b 181 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 54 65 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site BWK49_RS22030 8c58a58549a49134fa188c21d2a45a3b 181 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 99 110 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site BWK49_RS22030 8c58a58549a49134fa188c21d2a45a3b 181 TIGRFAM TIGR01971 NuoI: NADH-quinone oxidoreductase, chain I 10 137 4.7E-43 T 06-07-2017 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS22030 8c58a58549a49134fa188c21d2a45a3b 181 Gene3D G3DSA:3.30.70.20 60 132 2.5E-19 T 06-07-2017 BWK49_RS22030 8c58a58549a49134fa188c21d2a45a3b 181 Gene3D G3DSA:1.10.1060.10 28 59 9.4E-4 T 06-07-2017 BWK49_RS22030 8c58a58549a49134fa188c21d2a45a3b 181 Pfam PF12838 4Fe-4S dicluster domain 53 113 3.6E-12 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain BWK49_RS22030 8c58a58549a49134fa188c21d2a45a3b 181 SUPERFAMILY SSF54862 27 142 5.86E-28 T 06-07-2017 BWK49_RS22030 8c58a58549a49134fa188c21d2a45a3b 181 Hamap MF_01351 NAD(P)H-quinone oxidoreductase subunit I, chloroplastic [ndhI]. 1 143 27.578 T 06-07-2017 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS24590 469d7e7c577e347adf71ee97a49bcd78 267 Gene3D G3DSA:2.30.30.30 206 267 1.9E-28 T 06-07-2017 IPR014722 Ribosomal protein L2 domain 2 BWK49_RS24590 469d7e7c577e347adf71ee97a49bcd78 267 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 75 267 23.333 T 06-07-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 BWK49_RS24590 469d7e7c577e347adf71ee97a49bcd78 267 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 78 266 4.7E-66 T 06-07-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 BWK49_RS24590 469d7e7c577e347adf71ee97a49bcd78 267 SMART SM00739 213 240 0.0086 T 06-07-2017 IPR005824 KOW BWK49_RS24590 469d7e7c577e347adf71ee97a49bcd78 267 Pfam PF02357 Transcription termination factor nusG 77 179 2.0E-24 T 06-07-2017 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 BWK49_RS24590 469d7e7c577e347adf71ee97a49bcd78 267 Gene3D G3DSA:3.30.70.940 77 180 3.4E-41 T 06-07-2017 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 BWK49_RS24590 469d7e7c577e347adf71ee97a49bcd78 267 ProSitePatterns PS01014 Transcription termination factor nusG signature. 250 259 - T 06-07-2017 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site BWK49_RS24590 469d7e7c577e347adf71ee97a49bcd78 267 PRINTS PR00338 Transcription termination factor NUSG signature 130 142 1.7E-19 T 06-07-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 BWK49_RS24590 469d7e7c577e347adf71ee97a49bcd78 267 PRINTS PR00338 Transcription termination factor NUSG signature 243 259 1.7E-19 T 06-07-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 BWK49_RS24590 469d7e7c577e347adf71ee97a49bcd78 267 PRINTS PR00338 Transcription termination factor NUSG signature 225 240 1.7E-19 T 06-07-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 BWK49_RS24590 469d7e7c577e347adf71ee97a49bcd78 267 SMART SM00738 75 183 1.0E-48 T 06-07-2017 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 BWK49_RS24590 469d7e7c577e347adf71ee97a49bcd78 267 SUPERFAMILY SSF50104 211 267 9.23E-17 T 06-07-2017 IPR008991 Translation protein SH3-like domain BWK49_RS24590 469d7e7c577e347adf71ee97a49bcd78 267 SUPERFAMILY SSF82679 77 180 1.7E-35 T 06-07-2017 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 BWK49_RS21330 a4be8054311abb81ac74c85e3898b85c 721 Gene3D G3DSA:3.20.70.20 114 304 1.9E-53 T 06-07-2017 BWK49_RS21330 a4be8054311abb81ac74c85e3898b85c 721 Gene3D G3DSA:3.20.70.20 357 520 1.9E-53 T 06-07-2017 BWK49_RS21330 a4be8054311abb81ac74c85e3898b85c 721 Gene3D G3DSA:3.20.70.20 584 698 1.9E-53 T 06-07-2017 BWK49_RS21330 a4be8054311abb81ac74c85e3898b85c 721 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 573 595 - T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 BWK49_RS21330 a4be8054311abb81ac74c85e3898b85c 721 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 110 703 1.4E-160 T 06-07-2017 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 BWK49_RS21330 a4be8054311abb81ac74c85e3898b85c 721 TIGRFAM TIGR04170 RNR_1b_NrdE: ribonucleoside-diphosphate reductase, class 1b, alpha subunit 22 721 0.0 T 06-07-2017 IPR026459 Ribonucleotide reductase, class 1b, subunit NrdE KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 BWK49_RS21330 a4be8054311abb81ac74c85e3898b85c 721 PRINTS PR01183 Ribonucleotide reductase large chain signature 258 277 2.2E-33 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 BWK49_RS21330 a4be8054311abb81ac74c85e3898b85c 721 PRINTS PR01183 Ribonucleotide reductase large chain signature 584 611 2.2E-33 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 BWK49_RS21330 a4be8054311abb81ac74c85e3898b85c 721 PRINTS PR01183 Ribonucleotide reductase large chain signature 472 494 2.2E-33 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 BWK49_RS21330 a4be8054311abb81ac74c85e3898b85c 721 PRINTS PR01183 Ribonucleotide reductase large chain signature 389 400 2.2E-33 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 BWK49_RS21330 a4be8054311abb81ac74c85e3898b85c 721 PRINTS PR01183 Ribonucleotide reductase large chain signature 433 456 2.2E-33 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 BWK49_RS21330 a4be8054311abb81ac74c85e3898b85c 721 PRINTS PR01183 Ribonucleotide reductase large chain signature 500 523 2.2E-33 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 BWK49_RS21330 a4be8054311abb81ac74c85e3898b85c 721 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 106 178 4.8E-11 T 06-07-2017 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 BWK49_RS21330 a4be8054311abb81ac74c85e3898b85c 721 Pfam PF08343 Ribonucleotide reductase N-terminal 23 104 6.4E-32 T 06-07-2017 IPR013554 Ribonucleotide reductase N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 BWK49_RS21330 a4be8054311abb81ac74c85e3898b85c 721 SUPERFAMILY SSF51998 182 705 2.56E-187 T 06-07-2017 BWK49_RS21330 a4be8054311abb81ac74c85e3898b85c 721 SUPERFAMILY SSF48168 21 181 3.27E-61 T 06-07-2017 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 BWK49_RS21330 a4be8054311abb81ac74c85e3898b85c 721 Pfam PF02867 Ribonucleotide reductase, barrel domain 183 700 7.8E-145 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 BWK49_RS16690 1368387d66786fc80575b63c6a80a19a 420 SUPERFAMILY SSF55174 326 417 2.75E-15 T 06-07-2017 BWK49_RS16690 1368387d66786fc80575b63c6a80a19a 420 SUPERFAMILY SSF52374 3 322 3.15E-92 T 06-07-2017 BWK49_RS16690 1368387d66786fc80575b63c6a80a19a 420 Gene3D G3DSA:3.40.50.620 2 231 1.1E-88 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold BWK49_RS16690 1368387d66786fc80575b63c6a80a19a 420 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 2 416 2.3E-108 T 06-07-2017 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 BWK49_RS16690 1368387d66786fc80575b63c6a80a19a 420 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 38 48 - T 06-07-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 BWK49_RS16690 1368387d66786fc80575b63c6a80a19a 420 Gene3D G3DSA:1.10.240.10 232 315 1.0E-36 T 06-07-2017 BWK49_RS16690 1368387d66786fc80575b63c6a80a19a 420 Gene3D G3DSA:3.10.290.10 316 418 2.5E-28 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 BWK49_RS16690 1368387d66786fc80575b63c6a80a19a 420 Hamap MF_02006 Tyrosine--tRNA ligase [tyrS]. 1 419 41.881 T 06-07-2017 IPR024107 Tyrosine-tRNA ligase, bacterial-type, type 1 GO:0004831 KEGG: 00970+6.1.1.1 BWK49_RS16690 1368387d66786fc80575b63c6a80a19a 420 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 160 175 2.5E-30 T 06-07-2017 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 BWK49_RS16690 1368387d66786fc80575b63c6a80a19a 420 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 181 203 2.5E-30 T 06-07-2017 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 BWK49_RS16690 1368387d66786fc80575b63c6a80a19a 420 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 42 64 2.5E-30 T 06-07-2017 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 BWK49_RS16690 1368387d66786fc80575b63c6a80a19a 420 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 214 226 2.5E-30 T 06-07-2017 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 BWK49_RS16690 1368387d66786fc80575b63c6a80a19a 420 Pfam PF00579 tRNA synthetases class I (W and Y) 27 322 3.3E-83 T 06-07-2017 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 BWK49_RS16690 1368387d66786fc80575b63c6a80a19a 420 Pfam PF01479 S4 domain 356 390 1.7E-5 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 BWK49_RS16690 1368387d66786fc80575b63c6a80a19a 420 SMART SM00363 354 415 9.9E-4 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 BWK49_RS16290 0b0e6fa2fa825e677a93c3af5a616397 453 SUPERFAMILY SSF53098 120 271 5.31E-5 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS16290 0b0e6fa2fa825e677a93c3af5a616397 453 Gene3D G3DSA:3.30.420.10 121 270 4.8E-6 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS16290 0b0e6fa2fa825e677a93c3af5a616397 453 Pfam PF00665 Integrase core domain 122 248 9.9E-10 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 BWK49_RS16520 0b0e6fa2fa825e677a93c3af5a616397 453 SUPERFAMILY SSF53098 120 271 5.31E-5 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS16520 0b0e6fa2fa825e677a93c3af5a616397 453 Gene3D G3DSA:3.30.420.10 121 270 4.8E-6 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS16520 0b0e6fa2fa825e677a93c3af5a616397 453 Pfam PF00665 Integrase core domain 122 248 9.9E-10 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 BWK49_RS15435 6bec95f1ab29731141b2c09040860934 454 Pfam PF00270 DEAD/DEAH box helicase 29 198 8.5E-44 T 06-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 BWK49_RS15435 6bec95f1ab29731141b2c09040860934 454 Gene3D G3DSA:3.40.50.300 214 372 1.0E-38 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS15435 6bec95f1ab29731141b2c09040860934 454 SMART SM00490 259 340 1.8E-25 T 06-07-2017 IPR001650 Helicase, C-terminal BWK49_RS15435 6bec95f1ab29731141b2c09040860934 454 Pfam PF00271 Helicase conserved C-terminal domain 242 340 4.7E-22 T 06-07-2017 IPR001650 Helicase, C-terminal BWK49_RS15435 6bec95f1ab29731141b2c09040860934 454 SUPERFAMILY SSF52540 79 357 1.08E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS15435 6bec95f1ab29731141b2c09040860934 454 SMART SM00487 24 224 8.9E-47 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain BWK49_RS15435 6bec95f1ab29731141b2c09040860934 454 Gene3D G3DSA:3.40.50.300 5 213 7.1E-66 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS13065 1ed48680e9af7f23688d0a9b97714975 522 SUPERFAMILY SSF53623 128 354 1.83E-68 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 BWK49_RS13065 1ed48680e9af7f23688d0a9b97714975 522 Pfam PF02875 Mur ligase family, glutamate ligase domain 360 443 2.6E-21 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 BWK49_RS13065 1ed48680e9af7f23688d0a9b97714975 522 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 45 514 7.5E-154 T 06-07-2017 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 BWK49_RS13065 1ed48680e9af7f23688d0a9b97714975 522 Pfam PF08245 Mur ligase middle domain 137 340 4.0E-45 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 BWK49_RS13065 1ed48680e9af7f23688d0a9b97714975 522 SUPERFAMILY SSF63418 41 126 1.26E-17 T 06-07-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 BWK49_RS13065 1ed48680e9af7f23688d0a9b97714975 522 SUPERFAMILY SSF53244 360 516 2.75E-45 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 BWK49_RS13065 1ed48680e9af7f23688d0a9b97714975 522 Pfam PF01225 Mur ligase family, catalytic domain 47 98 6.8E-8 T 06-07-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 BWK49_RS13065 1ed48680e9af7f23688d0a9b97714975 522 Gene3D G3DSA:3.40.1390.10 42 127 2.8E-17 T 06-07-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 BWK49_RS13065 1ed48680e9af7f23688d0a9b97714975 522 Gene3D G3DSA:3.40.1190.10 128 363 1.5E-75 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 BWK49_RS13065 1ed48680e9af7f23688d0a9b97714975 522 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 23 514 32.414 T 06-07-2017 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 BWK49_RS13065 1ed48680e9af7f23688d0a9b97714975 522 Gene3D G3DSA:3.90.190.20 364 507 4.9E-51 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 BWK49_RS19370 2aa281ef3280822ef690e139a3b4b2e4 218 SUPERFAMILY SSF116726 133 215 7.32E-13 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 BWK49_RS19370 2aa281ef3280822ef690e139a3b4b2e4 218 SUPERFAMILY SSF51735 1 145 6.45E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS19370 2aa281ef3280822ef690e139a3b4b2e4 218 Gene3D G3DSA:3.30.70.1450 147 216 3.3E-8 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 BWK49_RS19370 2aa281ef3280822ef690e139a3b4b2e4 218 Pfam PF02254 TrkA-N domain 3 118 2.1E-24 T 06-07-2017 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 BWK49_RS19370 2aa281ef3280822ef690e139a3b4b2e4 218 Gene3D G3DSA:3.40.50.720 1 146 1.9E-31 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS19370 2aa281ef3280822ef690e139a3b4b2e4 218 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 1.6E-7 T 06-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 BWK49_RS19370 2aa281ef3280822ef690e139a3b4b2e4 218 PRINTS PR00335 TrkA potassium uptake protein signature 72 86 1.6E-7 T 06-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 BWK49_RS19370 2aa281ef3280822ef690e139a3b4b2e4 218 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 1.6E-7 T 06-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 BWK49_RS19370 2aa281ef3280822ef690e139a3b4b2e4 218 Pfam PF02080 TrkA-C domain 149 216 3.9E-10 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 BWK49_RS20300 c4a02e1f8a043b34e9c2975377039566 80 SUPERFAMILY SSF54814 19 63 5.04E-8 T 06-07-2017 IPR009019 K homology domain, prokaryotic type GO:0003723 BWK49_RS20300 c4a02e1f8a043b34e9c2975377039566 80 Pfam PF13083 KH domain 7 67 2.6E-20 T 06-07-2017 BWK49_RS20300 c4a02e1f8a043b34e9c2975377039566 80 Hamap MF_00088 UPF0109 protein . 5 76 20.915 T 06-07-2017 IPR020627 Uncharacterised protein family UPF0109 BWK49_RS20300 c4a02e1f8a043b34e9c2975377039566 80 Gene3D G3DSA:3.30.300.120 7 64 1.4E-7 T 06-07-2017 BWK49_RS08620 c266f86cdeb37a22748542c8bf614a9a 290 Gene3D G3DSA:3.40.190.10 32 138 3.5E-16 T 06-07-2017 BWK49_RS08620 c266f86cdeb37a22748542c8bf614a9a 290 Gene3D G3DSA:3.40.190.10 240 288 3.5E-16 T 06-07-2017 BWK49_RS08620 c266f86cdeb37a22748542c8bf614a9a 290 SUPERFAMILY SSF53850 33 288 1.59E-23 T 06-07-2017 BWK49_RS08620 c266f86cdeb37a22748542c8bf614a9a 290 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 190 285 1.5E-11 T 06-07-2017 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 BWK49_RS08620 c266f86cdeb37a22748542c8bf614a9a 290 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 33 148 3.3E-7 T 06-07-2017 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 BWK49_RS15030 6c13aa1236966e546aedbef1e752ac54 207 Pfam PF13523 Acetyltransferase (GNAT) domain 48 189 1.5E-42 T 06-07-2017 BWK49_RS15030 6c13aa1236966e546aedbef1e752ac54 207 Gene3D G3DSA:3.40.630.30 27 201 6.7E-49 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase BWK49_RS15030 6c13aa1236966e546aedbef1e752ac54 207 SUPERFAMILY SSF55729 11 201 1.04E-53 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase BWK49_RS15030 6c13aa1236966e546aedbef1e752ac54 207 SMART SM01006 43 89 4.9E-13 T 06-07-2017 IPR019432 Siderophore biosynthesis protein, conserved domain BWK49_RS10940 63d414040fb95342d630f51aeaec8034 390 PRINTS PR00385 P450 superfamily signature 338 349 2.1E-6 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS10940 63d414040fb95342d630f51aeaec8034 390 PRINTS PR00385 P450 superfamily signature 227 244 2.1E-6 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS10940 63d414040fb95342d630f51aeaec8034 390 PRINTS PR00385 P450 superfamily signature 262 273 2.1E-6 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS10940 63d414040fb95342d630f51aeaec8034 390 PRINTS PR00385 P450 superfamily signature 329 338 2.1E-6 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS10940 63d414040fb95342d630f51aeaec8034 390 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 331 340 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 BWK49_RS10940 63d414040fb95342d630f51aeaec8034 390 PRINTS PR00359 B-class P450 signature 139 154 2.6E-39 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS10940 63d414040fb95342d630f51aeaec8034 390 PRINTS PR00359 B-class P450 signature 76 87 2.6E-39 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS10940 63d414040fb95342d630f51aeaec8034 390 PRINTS PR00359 B-class P450 signature 262 273 2.6E-39 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS10940 63d414040fb95342d630f51aeaec8034 390 PRINTS PR00359 B-class P450 signature 329 338 2.6E-39 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS10940 63d414040fb95342d630f51aeaec8034 390 PRINTS PR00359 B-class P450 signature 338 349 2.6E-39 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS10940 63d414040fb95342d630f51aeaec8034 390 PRINTS PR00359 B-class P450 signature 279 306 2.6E-39 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS10940 63d414040fb95342d630f51aeaec8034 390 PRINTS PR00359 B-class P450 signature 122 138 2.6E-39 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS10940 63d414040fb95342d630f51aeaec8034 390 Gene3D G3DSA:1.10.630.10 4 386 2.2E-123 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS10940 63d414040fb95342d630f51aeaec8034 390 Pfam PF00067 Cytochrome P450 175 359 9.4E-26 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS10940 63d414040fb95342d630f51aeaec8034 390 SUPERFAMILY SSF48264 6 386 3.8E-97 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS24845 f575a0067cceeb9d39c34d99dc17115c 413 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 10 317 1.9E-69 T 06-07-2017 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 BWK49_RS24845 f575a0067cceeb9d39c34d99dc17115c 413 SUPERFAMILY SSF51905 270 356 1.05E-43 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS24845 f575a0067cceeb9d39c34d99dc17115c 413 SUPERFAMILY SSF51905 9 172 1.05E-43 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS24845 f575a0067cceeb9d39c34d99dc17115c 413 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 298 314 6.2E-10 T 06-07-2017 BWK49_RS24845 f575a0067cceeb9d39c34d99dc17115c 413 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 283 298 6.2E-10 T 06-07-2017 BWK49_RS24845 f575a0067cceeb9d39c34d99dc17115c 413 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 9 31 6.2E-10 T 06-07-2017 BWK49_RS24845 f575a0067cceeb9d39c34d99dc17115c 413 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 151 166 6.2E-10 T 06-07-2017 BWK49_RS24845 f575a0067cceeb9d39c34d99dc17115c 413 Gene3D G3DSA:3.30.9.10 173 326 5.0E-44 T 06-07-2017 BWK49_RS24845 f575a0067cceeb9d39c34d99dc17115c 413 Pfam PF01494 FAD binding domain 8 178 1.2E-11 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 BWK49_RS24845 f575a0067cceeb9d39c34d99dc17115c 413 Gene3D G3DSA:3.50.50.60 10 172 2.5E-23 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS12295 c09069ebe5f44d2cc6bafd99f638c252 135 Gene3D G3DSA:3.40.50.1010 9 126 4.2E-18 T 06-07-2017 IPR029060 PIN domain-like BWK49_RS12295 c09069ebe5f44d2cc6bafd99f638c252 135 Pfam PF01850 PIN domain 9 125 2.5E-16 T 06-07-2017 IPR002716 PIN domain BWK49_RS12295 c09069ebe5f44d2cc6bafd99f638c252 135 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 8 131 13.726 T 06-07-2017 IPR022907 VapC family GO:0004540 BWK49_RS12295 c09069ebe5f44d2cc6bafd99f638c252 135 SUPERFAMILY SSF88723 9 127 4.21E-20 T 06-07-2017 IPR029060 PIN domain-like BWK49_RS25990 1a819e561bb0c352fca2b310c8f341e0 146 Gene3D G3DSA:3.40.250.10 8 145 8.1E-44 T 06-07-2017 IPR001763 Rhodanese-like domain BWK49_RS25990 1a819e561bb0c352fca2b310c8f341e0 146 Pfam PF00581 Rhodanese-like domain 15 122 5.2E-7 T 06-07-2017 IPR001763 Rhodanese-like domain BWK49_RS25990 1a819e561bb0c352fca2b310c8f341e0 146 SMART SM00450 14 130 4.6E-13 T 06-07-2017 IPR001763 Rhodanese-like domain BWK49_RS25990 1a819e561bb0c352fca2b310c8f341e0 146 SUPERFAMILY SSF52821 9 145 7.86E-21 T 06-07-2017 IPR001763 Rhodanese-like domain BWK49_RS07070 6df92b2eda886213a9e2fc184f78a987 57 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 48 1.7E-12 T 06-07-2017 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS07070 6df92b2eda886213a9e2fc184f78a987 57 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 53 13.139 T 06-07-2017 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS07070 6df92b2eda886213a9e2fc184f78a987 57 SUPERFAMILY SSF57829 1 38 2.26E-7 T 06-07-2017 IPR011332 Zinc-binding ribosomal protein GO:0006412 BWK49_RS07070 6df92b2eda886213a9e2fc184f78a987 57 Pfam PF01783 Ribosomal L32p protein family 2 46 2.5E-11 T 06-07-2017 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS10805 4ce22937f910b53f96010ab550c2c474 412 PRINTS PR00359 B-class P450 signature 303 330 5.3E-40 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS10805 4ce22937f910b53f96010ab550c2c474 412 PRINTS PR00359 B-class P450 signature 104 115 5.3E-40 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS10805 4ce22937f910b53f96010ab550c2c474 412 PRINTS PR00359 B-class P450 signature 151 167 5.3E-40 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS10805 4ce22937f910b53f96010ab550c2c474 412 PRINTS PR00359 B-class P450 signature 331 346 5.3E-40 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS10805 4ce22937f910b53f96010ab550c2c474 412 PRINTS PR00359 B-class P450 signature 361 372 5.3E-40 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS10805 4ce22937f910b53f96010ab550c2c474 412 PRINTS PR00359 B-class P450 signature 352 361 5.3E-40 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS10805 4ce22937f910b53f96010ab550c2c474 412 PRINTS PR00359 B-class P450 signature 205 227 5.3E-40 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS10805 4ce22937f910b53f96010ab550c2c474 412 PRINTS PR00359 B-class P450 signature 286 297 5.3E-40 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS10805 4ce22937f910b53f96010ab550c2c474 412 PRINTS PR00359 B-class P450 signature 168 183 5.3E-40 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS10805 4ce22937f910b53f96010ab550c2c474 412 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 354 363 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 BWK49_RS10805 4ce22937f910b53f96010ab550c2c474 412 Pfam PF00067 Cytochrome P450 199 381 4.1E-22 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS10805 4ce22937f910b53f96010ab550c2c474 412 SUPERFAMILY SSF48264 32 411 9.04E-80 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS10805 4ce22937f910b53f96010ab550c2c474 412 Gene3D G3DSA:1.10.630.10 27 411 1.2E-99 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS06450 f8c8b8d80763f729046f2218416406f7 467 Gene3D G3DSA:3.40.50.980 4 148 9.5E-36 T 06-07-2017 BWK49_RS06450 f8c8b8d80763f729046f2218416406f7 467 Pfam PF00501 AMP-binding enzyme 5 378 1.5E-90 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS06450 f8c8b8d80763f729046f2218416406f7 467 SUPERFAMILY SSF56801 3 467 2.88E-138 T 06-07-2017 BWK49_RS06450 f8c8b8d80763f729046f2218416406f7 467 Pfam PF13193 AMP-binding enzyme C-terminal domain 387 460 1.4E-21 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS06450 f8c8b8d80763f729046f2218416406f7 467 Gene3D G3DSA:3.30.300.30 376 467 2.4E-30 T 06-07-2017 BWK49_RS06450 f8c8b8d80763f729046f2218416406f7 467 ProSitePatterns PS00455 Putative AMP-binding domain signature. 142 153 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS06450 f8c8b8d80763f729046f2218416406f7 467 Gene3D G3DSA:2.30.38.10 306 369 3.4E-20 T 06-07-2017 BWK49_RS06450 f8c8b8d80763f729046f2218416406f7 467 Gene3D G3DSA:3.40.50.980 149 296 1.6E-36 T 06-07-2017 BWK49_RS19640 6105ea005257109e42c47c33b21097ac 875 SMART SM00843 784 849 4.7E-32 T 06-07-2017 IPR018541 FtsK gamma domain BWK49_RS19640 6105ea005257109e42c47c33b21097ac 875 Pfam PF01580 FtsK/SpoIIIE family 483 683 3.7E-64 T 06-07-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 BWK49_RS19640 6105ea005257109e42c47c33b21097ac 875 Pfam PF09397 Ftsk gamma domain 789 846 1.1E-23 T 06-07-2017 IPR018541 FtsK gamma domain BWK49_RS19640 6105ea005257109e42c47c33b21097ac 875 Gene3D G3DSA:3.40.50.300 457 749 1.5E-83 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS19640 6105ea005257109e42c47c33b21097ac 875 SUPERFAMILY SSF46785 785 850 1.02E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS19640 6105ea005257109e42c47c33b21097ac 875 SUPERFAMILY SSF52540 457 753 5.76E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS19640 6105ea005257109e42c47c33b21097ac 875 Pfam PF13491 4TM region of DNA translocase FtsK/SpoIIIE 149 271 6.9E-6 T 06-07-2017 IPR025199 DNA translocase FtsK, 4TM region BWK49_RS15365 537c81e91e287a14d20c44a48efb1fe1 407 SUPERFAMILY SSF89796 4 406 4.19E-97 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS15365 537c81e91e287a14d20c44a48efb1fe1 407 Gene3D G3DSA:3.40.50.10540 4 225 7.8E-78 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS15365 537c81e91e287a14d20c44a48efb1fe1 407 Gene3D G3DSA:3.40.50.10540 313 406 7.8E-78 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS15365 537c81e91e287a14d20c44a48efb1fe1 407 Gene3D G3DSA:3.30.1540.10 245 312 1.0E-12 T 06-07-2017 BWK49_RS15365 537c81e91e287a14d20c44a48efb1fe1 407 Pfam PF02515 CoA-transferase family III 6 383 1.4E-83 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 BWK49_RS17560 b3525a37a54850935d76d1b0ac8605b8 308 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 135 149 - T 06-07-2017 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 BWK49_RS17560 b3525a37a54850935d76d1b0ac8605b8 308 SUPERFAMILY SSF55174 14 66 5.18E-5 T 06-07-2017 BWK49_RS17560 b3525a37a54850935d76d1b0ac8605b8 308 SUPERFAMILY SSF55120 74 305 2.4E-66 T 06-07-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 BWK49_RS17560 b3525a37a54850935d76d1b0ac8605b8 308 SMART SM00363 15 72 7.9E-4 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 BWK49_RS17560 b3525a37a54850935d76d1b0ac8605b8 308 Pfam PF00849 RNA pseudouridylate synthase 90 243 7.2E-30 T 06-07-2017 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 BWK49_RS17560 b3525a37a54850935d76d1b0ac8605b8 308 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 12 305 1.3E-86 T 06-07-2017 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 BWK49_RS17560 b3525a37a54850935d76d1b0ac8605b8 308 Gene3D G3DSA:3.10.290.10 14 50 1.1E-4 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 BWK49_RS02555 3d8d608f1e58a0f582f43a4a4f5a9274 433 SUPERFAMILY SSF55931 45 263 8.34E-48 T 06-07-2017 BWK49_RS02555 3d8d608f1e58a0f582f43a4a4f5a9274 433 SUPERFAMILY SSF55931 301 429 8.34E-48 T 06-07-2017 BWK49_RS02555 3d8d608f1e58a0f582f43a4a4f5a9274 433 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 50 354 1.6E-81 T 06-07-2017 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 BWK49_RS02555 3d8d608f1e58a0f582f43a4a4f5a9274 433 PIRSF PIRSF017901 1 431 2.9E-113 T 06-07-2017 BWK49_RS02555 3d8d608f1e58a0f582f43a4a4f5a9274 433 Hamap MF_02034 Glutamate--cysteine ligase EgtA [egtA]. 25 409 28.952 T 06-07-2017 IPR017809 Glutamate--cysteine ligase EgtA, Actinobacteria GO:0004357|GO:0052699 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 BWK49_RS02555 3d8d608f1e58a0f582f43a4a4f5a9274 433 TIGRFAM TIGR03444 EgtA_Cys_ligase: ergothioneine biosynthesis glutamate--cysteine ligase EgtA 36 411 2.2E-160 T 06-07-2017 IPR017809 Glutamate--cysteine ligase EgtA, Actinobacteria GO:0004357|GO:0052699 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 BWK49_RS23215 6902813c78353b86fb03f994418608d1 262 SUPERFAMILY SSF88946 13 112 2.51E-26 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS23215 6902813c78353b86fb03f994418608d1 262 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 39 261 5.9E-35 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS23215 6902813c78353b86fb03f994418608d1 262 Pfam PF04539 Sigma-70 region 3 126 190 1.2E-11 T 06-07-2017 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS23215 6902813c78353b86fb03f994418608d1 262 SUPERFAMILY SSF88659 179 261 9.91E-18 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS23215 6902813c78353b86fb03f994418608d1 262 Gene3D G3DSA:1.10.10.10 112 165 1.6E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS23215 6902813c78353b86fb03f994418608d1 262 Pfam PF04542 Sigma-70 region 2 44 112 3.5E-13 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS23215 6902813c78353b86fb03f994418608d1 262 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 37 262 1.1E-93 T 06-07-2017 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS23215 6902813c78353b86fb03f994418608d1 262 SUPERFAMILY SSF88659 116 192 4.36E-14 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS23215 6902813c78353b86fb03f994418608d1 262 Gene3D G3DSA:1.10.10.10 202 262 2.1E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS23215 6902813c78353b86fb03f994418608d1 262 PRINTS PR00046 Major sigma-70 factor signature 231 246 3.1E-9 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS23215 6902813c78353b86fb03f994418608d1 262 PRINTS PR00046 Major sigma-70 factor signature 67 80 3.1E-9 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS23215 6902813c78353b86fb03f994418608d1 262 PRINTS PR00046 Major sigma-70 factor signature 214 226 3.1E-9 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS23215 6902813c78353b86fb03f994418608d1 262 PRINTS PR00046 Major sigma-70 factor signature 246 257 3.1E-9 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS23215 6902813c78353b86fb03f994418608d1 262 Gene3D G3DSA:1.10.601.10 24 111 7.5E-17 T 06-07-2017 BWK49_RS23215 6902813c78353b86fb03f994418608d1 262 Pfam PF04545 Sigma-70, region 4 210 259 1.4E-17 T 06-07-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS17575 fe41a572f23744e08d97e287226c571f 469 Gene3D G3DSA:1.10.150.20 168 241 2.4E-21 T 06-07-2017 BWK49_RS17575 fe41a572f23744e08d97e287226c571f 469 SUPERFAMILY SSF100879 243 342 1.11E-23 T 06-07-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 BWK49_RS17575 fe41a572f23744e08d97e287226c571f 469 Gene3D G3DSA:3.30.70.270 71 167 2.1E-17 T 06-07-2017 BWK49_RS17575 fe41a572f23744e08d97e287226c571f 469 Pfam PF11798 IMS family HHH motif 170 200 2.2E-7 T 06-07-2017 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 BWK49_RS17575 fe41a572f23744e08d97e287226c571f 469 SUPERFAMILY SSF56672 3 241 9.78E-66 T 06-07-2017 BWK49_RS17575 fe41a572f23744e08d97e287226c571f 469 Pfam PF00817 impB/mucB/samB family 9 156 2.7E-33 T 06-07-2017 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 BWK49_RS17575 fe41a572f23744e08d97e287226c571f 469 Pfam PF11799 impB/mucB/samB family C-terminal domain 239 347 2.0E-17 T 06-07-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 BWK49_RS17575 fe41a572f23744e08d97e287226c571f 469 Gene3D G3DSA:3.30.1490.100 245 350 7.9E-28 T 06-07-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 BWK49_RS17575 fe41a572f23744e08d97e287226c571f 469 Hamap MF_01113 DNA polymerase IV [dinB]. 3 357 32.997 T 06-07-2017 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 BWK49_RS27115 2d933613eb0e93ff0010054556e342ca 195 SUPERFAMILY SSF46689 5 70 2.67E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS27115 2d933613eb0e93ff0010054556e342ca 195 SUPERFAMILY SSF48498 74 185 7.79E-20 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS27115 2d933613eb0e93ff0010054556e342ca 195 Gene3D G3DSA:1.10.357.10 5 185 5.8E-22 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS27115 2d933613eb0e93ff0010054556e342ca 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 52 6.9E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS01520 b10b7a3bbc2748ab4195daf9c7d61bc8 377 PRINTS PR00412 Epoxide hydrolase signature 129 144 1.3E-17 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS01520 b10b7a3bbc2748ab4195daf9c7d61bc8 377 PRINTS PR00412 Epoxide hydrolase signature 319 335 1.3E-17 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS01520 b10b7a3bbc2748ab4195daf9c7d61bc8 377 PRINTS PR00412 Epoxide hydrolase signature 100 118 1.3E-17 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS01520 b10b7a3bbc2748ab4195daf9c7d61bc8 377 PRINTS PR00412 Epoxide hydrolase signature 350 372 1.3E-17 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS01520 b10b7a3bbc2748ab4195daf9c7d61bc8 377 PRINTS PR00412 Epoxide hydrolase signature 174 187 1.3E-17 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS01520 b10b7a3bbc2748ab4195daf9c7d61bc8 377 PIRSF PIRSF001112 1 377 3.9E-142 T 06-07-2017 IPR016292 Epoxide hydrolase GO:0033961 KEGG: 00980+3.3.2.9|Reactome: R-HSA-211945 BWK49_RS01520 b10b7a3bbc2748ab4195daf9c7d61bc8 377 Gene3D G3DSA:3.40.50.1820 2 376 1.2E-147 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS01520 b10b7a3bbc2748ab4195daf9c7d61bc8 377 Pfam PF06441 Epoxide hydrolase N terminus 4 109 2.6E-37 T 06-07-2017 IPR010497 Epoxide hydrolase, N-terminal KEGG: 00980+3.3.2.9|Reactome: R-HSA-211945 BWK49_RS01520 b10b7a3bbc2748ab4195daf9c7d61bc8 377 SUPERFAMILY SSF53474 3 374 6.53E-106 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS07825 228a296e7674204ff442d38aa325607a 468 Gene3D G3DSA:1.20.200.10 136 401 3.0E-96 T 06-07-2017 BWK49_RS07825 228a296e7674204ff442d38aa325607a 468 Pfam PF00206 Lyase 16 340 1.5E-103 T 06-07-2017 IPR022761 Fumarate lyase, N-terminal BWK49_RS07825 228a296e7674204ff442d38aa325607a 468 Gene3D G3DSA:1.10.275.10 7 135 2.0E-52 T 06-07-2017 IPR024083 Fumarase/histidase, N-terminal BWK49_RS07825 228a296e7674204ff442d38aa325607a 468 Pfam PF10415 Fumarase C C-terminus 406 462 2.0E-18 T 06-07-2017 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 BWK49_RS07825 228a296e7674204ff442d38aa325607a 468 PRINTS PR00149 Fumarate lyase superfamily signature 131 149 1.6E-34 T 06-07-2017 IPR000362 Fumarate lyase family BWK49_RS07825 228a296e7674204ff442d38aa325607a 468 PRINTS PR00149 Fumarate lyase superfamily signature 269 296 1.6E-34 T 06-07-2017 IPR000362 Fumarate lyase family BWK49_RS07825 228a296e7674204ff442d38aa325607a 468 PRINTS PR00149 Fumarate lyase superfamily signature 177 195 1.6E-34 T 06-07-2017 IPR000362 Fumarate lyase family BWK49_RS07825 228a296e7674204ff442d38aa325607a 468 PRINTS PR00149 Fumarate lyase superfamily signature 315 331 1.6E-34 T 06-07-2017 IPR000362 Fumarate lyase family BWK49_RS07825 228a296e7674204ff442d38aa325607a 468 ProSitePatterns PS00163 Fumarate lyases signature. 315 324 - T 06-07-2017 IPR020557 Fumarate lyase, conserved site GO:0003824 BWK49_RS07825 228a296e7674204ff442d38aa325607a 468 SUPERFAMILY SSF48557 8 463 2.04E-138 T 06-07-2017 IPR008948 L-Aspartase-like GO:0003824 BWK49_RS07825 228a296e7674204ff442d38aa325607a 468 Gene3D G3DSA:1.10.40.30 406 461 7.7E-20 T 06-07-2017 BWK49_RS07825 228a296e7674204ff442d38aa325607a 468 Hamap MF_00743 Fumarate hydratase class II [fumC]. 8 464 79.704 T 06-07-2017 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 BWK49_RS02345 e739efd542d6d2abd92d789c5a476bda 451 Pfam PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain 4 259 1.4E-87 T 06-07-2017 IPR004255 O-acyltransferase, WSD1, N-terminal GO:0004144|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 BWK49_RS02345 e739efd542d6d2abd92d789c5a476bda 451 SUPERFAMILY SSF52777 79 156 2.11E-6 T 06-07-2017 BWK49_RS02345 e739efd542d6d2abd92d789c5a476bda 451 TIGRFAM TIGR02946 acyl_WS_DGAT: acyltransferase, WS/DGAT/MGAT 4 448 6.8E-155 T 06-07-2017 IPR014292 Acyltransferase, WS/DGAT/MGAT GO:0016746|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 BWK49_RS02345 e739efd542d6d2abd92d789c5a476bda 451 Pfam PF06974 Protein of unknown function (DUF1298) 300 445 9.7E-36 T 06-07-2017 IPR009721 O-acyltransferase WSD1, C-terminal GO:0004144 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 BWK49_RS11360 49a1e66e85d0dbcd60de3a0a6328e7dc 1167 Gene3D G3DSA:2.30.38.10 865 941 3.8E-24 T 06-07-2017 BWK49_RS11360 49a1e66e85d0dbcd60de3a0a6328e7dc 1167 Pfam PF08415 Nonribosomal peptide synthase 417 473 5.5E-15 T 06-07-2017 IPR013624 Non-ribosomal peptide synthetase BWK49_RS11360 49a1e66e85d0dbcd60de3a0a6328e7dc 1167 SUPERFAMILY SSF47336 9 116 9.81E-14 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS11360 49a1e66e85d0dbcd60de3a0a6328e7dc 1167 Gene3D G3DSA:3.40.50.980 703 856 1.8E-35 T 06-07-2017 BWK49_RS11360 49a1e66e85d0dbcd60de3a0a6328e7dc 1167 SMART SM00823 Phosphopantetheine attachment site 8 78 0.18 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS11360 49a1e66e85d0dbcd60de3a0a6328e7dc 1167 SMART SM00823 Phosphopantetheine attachment site 1063 1133 0.043 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS11360 49a1e66e85d0dbcd60de3a0a6328e7dc 1167 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1087 1102 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site BWK49_RS11360 49a1e66e85d0dbcd60de3a0a6328e7dc 1167 ProSitePatterns PS00455 Putative AMP-binding domain signature. 697 708 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS11360 49a1e66e85d0dbcd60de3a0a6328e7dc 1167 Gene3D G3DSA:1.10.1200.10 9 76 5.3E-10 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS11360 49a1e66e85d0dbcd60de3a0a6328e7dc 1167 Gene3D G3DSA:1.10.1200.10 1068 1132 5.1E-21 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS11360 49a1e66e85d0dbcd60de3a0a6328e7dc 1167 SUPERFAMILY SSF47336 1056 1129 1.83E-14 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS11360 49a1e66e85d0dbcd60de3a0a6328e7dc 1167 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 580 975 8.3E-116 T 06-07-2017 IPR010071 Amino acid adenylation domain BWK49_RS11360 49a1e66e85d0dbcd60de3a0a6328e7dc 1167 Gene3D G3DSA:3.40.50.980 553 702 2.4E-34 T 06-07-2017 BWK49_RS11360 49a1e66e85d0dbcd60de3a0a6328e7dc 1167 Pfam PF00550 Phosphopantetheine attachment site 1065 1128 1.8E-10 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS11360 49a1e66e85d0dbcd60de3a0a6328e7dc 1167 Pfam PF00550 Phosphopantetheine attachment site 10 74 1.1E-8 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS11360 49a1e66e85d0dbcd60de3a0a6328e7dc 1167 Pfam PF00668 Condensation domain 102 394 6.2E-40 T 06-07-2017 IPR001242 Condensation domain BWK49_RS11360 49a1e66e85d0dbcd60de3a0a6328e7dc 1167 Gene3D G3DSA:3.30.300.30 948 1067 3.8E-25 T 06-07-2017 BWK49_RS11360 49a1e66e85d0dbcd60de3a0a6328e7dc 1167 SUPERFAMILY SSF56801 553 1075 5.1E-131 T 06-07-2017 BWK49_RS11360 49a1e66e85d0dbcd60de3a0a6328e7dc 1167 SUPERFAMILY SSF52777 283 523 4.34E-42 T 06-07-2017 BWK49_RS11360 49a1e66e85d0dbcd60de3a0a6328e7dc 1167 Pfam PF00501 AMP-binding enzyme 559 950 4.9E-88 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS11360 49a1e66e85d0dbcd60de3a0a6328e7dc 1167 SUPERFAMILY SSF52777 100 295 7.34E-21 T 06-07-2017 BWK49_RS25160 8d39ac2d8c5267319d71eb7f9b1a18b3 202 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 8 192 8.3E-40 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 BWK49_RS25160 8d39ac2d8c5267319d71eb7f9b1a18b3 202 SMART SM00855 6 158 3.0E-17 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 BWK49_RS25160 8d39ac2d8c5267319d71eb7f9b1a18b3 202 Gene3D G3DSA:3.40.50.1240 5 193 1.3E-36 T 06-07-2017 IPR029033 Histidine phosphatase superfamily BWK49_RS25160 8d39ac2d8c5267319d71eb7f9b1a18b3 202 SUPERFAMILY SSF53254 5 194 3.88E-41 T 06-07-2017 IPR029033 Histidine phosphatase superfamily BWK49_RS16595 fb2750d0bba10c0e85963afc83f50ae7 466 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 205 225 6.3E-7 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 BWK49_RS16595 fb2750d0bba10c0e85963afc83f50ae7 466 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 254 269 6.3E-7 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 BWK49_RS16595 fb2750d0bba10c0e85963afc83f50ae7 466 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 378 456 5.2E-25 T 06-07-2017 IPR032859 GTPase Der, C-terminal KH-domain-like BWK49_RS16595 fb2750d0bba10c0e85963afc83f50ae7 466 Gene3D G3DSA:3.30.300.20 385 458 4.9E-27 T 06-07-2017 IPR015946 K homology domain-like, alpha/beta BWK49_RS16595 fb2750d0bba10c0e85963afc83f50ae7 466 PIRSF PIRSF006485 28 464 3.5E-160 T 06-07-2017 IPR016484 GTP-binding protein EngA GO:0005525 BWK49_RS16595 fb2750d0bba10c0e85963afc83f50ae7 466 Pfam PF01926 50S ribosome-binding GTPase 204 322 6.0E-22 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 BWK49_RS16595 fb2750d0bba10c0e85963afc83f50ae7 466 Pfam PF01926 50S ribosome-binding GTPase 32 146 2.7E-22 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 BWK49_RS16595 fb2750d0bba10c0e85963afc83f50ae7 466 SUPERFAMILY SSF52540 31 192 2.17E-40 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS16595 fb2750d0bba10c0e85963afc83f50ae7 466 SMART SM00382 28 166 0.3 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS16595 fb2750d0bba10c0e85963afc83f50ae7 466 SMART SM00382 201 446 1.7 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS16595 fb2750d0bba10c0e85963afc83f50ae7 466 SUPERFAMILY SSF52540 164 460 4.64E-64 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS16595 fb2750d0bba10c0e85963afc83f50ae7 466 Hamap MF_00195 GTPase Der [der]. 29 459 34.726 T 06-07-2017 IPR016484 GTP-binding protein EngA GO:0005525 BWK49_RS16595 fb2750d0bba10c0e85963afc83f50ae7 466 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 30 456 1.0E-153 T 06-07-2017 IPR016484 GTP-binding protein EngA GO:0005525 BWK49_RS16595 fb2750d0bba10c0e85963afc83f50ae7 466 Gene3D G3DSA:3.40.50.300 203 384 2.6E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS16595 fb2750d0bba10c0e85963afc83f50ae7 466 Gene3D G3DSA:3.40.50.300 22 190 1.2E-39 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS16595 fb2750d0bba10c0e85963afc83f50ae7 466 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 203 368 1.1E-21 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 BWK49_RS16595 fb2750d0bba10c0e85963afc83f50ae7 466 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 31 160 3.2E-19 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 BWK49_RS02845 b4872e7721a1be224c8b25f0d3bcf46a 308 SUPERFAMILY SSF161098 89 289 3.05E-17 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS02845 b4872e7721a1be224c8b25f0d3bcf46a 308 Gene3D G3DSA:1.10.3720.10 87 303 9.6E-16 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS02845 b4872e7721a1be224c8b25f0d3bcf46a 308 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 307 1.2E-32 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS22175 50500263b7a6587599ed31c8e3a138dd 95 Pfam PF11829 Protein of unknown function (DUF3349) 7 91 1.6E-17 T 06-07-2017 IPR021784 Protein of unknown function DUF3349 BWK49_RS10550 e00ab7ea6810f9d49817c832da29cbac 464 Pfam PF08388 Group II intron, maturase-specific domain 343 414 4.0E-17 T 06-07-2017 IPR013597 Group II intron, maturase-specific BWK49_RS10550 e00ab7ea6810f9d49817c832da29cbac 464 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 29 407 1.8E-110 T 06-07-2017 IPR030931 Group II intron reverse transcriptase/maturase BWK49_RS10550 e00ab7ea6810f9d49817c832da29cbac 464 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 88 321 1.4E-39 T 06-07-2017 IPR000477 Reverse transcriptase domain BWK49_RS10550 e00ab7ea6810f9d49817c832da29cbac 464 SUPERFAMILY SSF56672 25 405 2.92E-48 T 06-07-2017 BWK49_RS23515 ced0af3c26984170c18938da461148d5 462 Gene3D G3DSA:3.90.1150.10 306 442 1.1E-45 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 BWK49_RS23515 ced0af3c26984170c18938da461148d5 462 PIRSF PIRSF001434 10 443 5.4E-127 T 06-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 BWK49_RS23515 ced0af3c26984170c18938da461148d5 462 Gene3D G3DSA:3.40.640.10 23 304 2.6E-116 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 BWK49_RS23515 ced0af3c26984170c18938da461148d5 462 SUPERFAMILY SSF53383 22 436 9.21E-120 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase BWK49_RS23515 ced0af3c26984170c18938da461148d5 462 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 218 232 - T 06-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 BWK49_RS23515 ced0af3c26984170c18938da461148d5 462 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 25 439 1.5E-137 T 06-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 BWK49_RS23515 ced0af3c26984170c18938da461148d5 462 TIGRFAM TIGR01326 OAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 24 439 3.8E-205 T 06-07-2017 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 KEGG: 00270+2.5.1.49|MetaCyc: PWY-5344|MetaCyc: PWY-7174 BWK49_RS15740 dbe183e172198a510cf9d85a9dabc33f 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 2.8E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15740 dbe183e172198a510cf9d85a9dabc33f 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 2.8E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15740 dbe183e172198a510cf9d85a9dabc33f 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 2.8E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15740 dbe183e172198a510cf9d85a9dabc33f 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 226 246 2.8E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15740 dbe183e172198a510cf9d85a9dabc33f 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 2.8E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15740 dbe183e172198a510cf9d85a9dabc33f 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 2.8E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15740 dbe183e172198a510cf9d85a9dabc33f 267 Gene3D G3DSA:3.40.50.720 3 263 4.1E-75 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS15740 dbe183e172198a510cf9d85a9dabc33f 267 SUPERFAMILY SSF51735 6 263 3.26E-72 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS15740 dbe183e172198a510cf9d85a9dabc33f 267 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS15740 dbe183e172198a510cf9d85a9dabc33f 267 TIGRFAM TIGR03971 SDR_subfam_1: SDR family mycofactocin-dependent oxidoreductase 4 264 1.6E-95 T 06-07-2017 IPR023985 Mycofactocin-dependent oxidoreductase BWK49_RS15740 dbe183e172198a510cf9d85a9dabc33f 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 5.8E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15740 dbe183e172198a510cf9d85a9dabc33f 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 5.8E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15740 dbe183e172198a510cf9d85a9dabc33f 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 5.8E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15740 dbe183e172198a510cf9d85a9dabc33f 267 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 263 8.6E-58 T 06-07-2017 BWK49_RS23760 cc849240b7beaf6688df59c01a8e9a9b 375 SMART SM01240 12 374 6.2E-13 T 06-07-2017 BWK49_RS23760 cc849240b7beaf6688df59c01a8e9a9b 375 TIGRFAM TIGR01304 IMP_DH_rel_2: IMP dehydrogenase family protein 2 373 4.9E-187 T 06-07-2017 IPR005992 IMP dehydrogenase-related 2 GO:0016491|GO:0055114 BWK49_RS23760 cc849240b7beaf6688df59c01a8e9a9b 375 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 18 302 7.6E-30 T 06-07-2017 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 BWK49_RS23760 cc849240b7beaf6688df59c01a8e9a9b 375 Gene3D G3DSA:3.20.20.70 15 371 1.4E-64 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 BWK49_RS23760 cc849240b7beaf6688df59c01a8e9a9b 375 SUPERFAMILY SSF51412 116 371 4.84E-55 T 06-07-2017 BWK49_RS23760 cc849240b7beaf6688df59c01a8e9a9b 375 SUPERFAMILY SSF51412 6 75 4.84E-55 T 06-07-2017 BWK49_RS11720 d5c46697968448c655b0f5c10f7d4ff5 419 PRINTS PR00359 B-class P450 signature 294 305 1.7E-32 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS11720 d5c46697968448c655b0f5c10f7d4ff5 419 PRINTS PR00359 B-class P450 signature 171 186 1.7E-32 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS11720 d5c46697968448c655b0f5c10f7d4ff5 419 PRINTS PR00359 B-class P450 signature 361 370 1.7E-32 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS11720 d5c46697968448c655b0f5c10f7d4ff5 419 PRINTS PR00359 B-class P450 signature 370 381 1.7E-32 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS11720 d5c46697968448c655b0f5c10f7d4ff5 419 PRINTS PR00359 B-class P450 signature 214 236 1.7E-32 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS11720 d5c46697968448c655b0f5c10f7d4ff5 419 PRINTS PR00359 B-class P450 signature 311 338 1.7E-32 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS11720 d5c46697968448c655b0f5c10f7d4ff5 419 PRINTS PR00359 B-class P450 signature 339 354 1.7E-32 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS11720 d5c46697968448c655b0f5c10f7d4ff5 419 PRINTS PR00359 B-class P450 signature 154 170 1.7E-32 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS11720 d5c46697968448c655b0f5c10f7d4ff5 419 PRINTS PR00359 B-class P450 signature 108 119 1.7E-32 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS11720 d5c46697968448c655b0f5c10f7d4ff5 419 Gene3D G3DSA:1.10.630.10 20 418 5.7E-88 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS11720 d5c46697968448c655b0f5c10f7d4ff5 419 SUPERFAMILY SSF48264 24 417 7.6E-76 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS11720 d5c46697968448c655b0f5c10f7d4ff5 419 Pfam PF00067 Cytochrome P450 276 394 2.4E-17 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS11720 d5c46697968448c655b0f5c10f7d4ff5 419 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 363 372 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 BWK49_RS26075 17feb2b2d28c17ab7be017d6d5e3f229 257 SUPERFAMILY SSF51735 3 248 3.08E-59 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS26075 17feb2b2d28c17ab7be017d6d5e3f229 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 8.4E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS26075 17feb2b2d28c17ab7be017d6d5e3f229 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 8.4E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS26075 17feb2b2d28c17ab7be017d6d5e3f229 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 8.4E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS26075 17feb2b2d28c17ab7be017d6d5e3f229 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 139 8.4E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS26075 17feb2b2d28c17ab7be017d6d5e3f229 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 8.4E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS26075 17feb2b2d28c17ab7be017d6d5e3f229 257 PIRSF PIRSF000126 2 252 1.3E-67 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS26075 17feb2b2d28c17ab7be017d6d5e3f229 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 1.5E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS26075 17feb2b2d28c17ab7be017d6d5e3f229 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 129 137 1.5E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS26075 17feb2b2d28c17ab7be017d6d5e3f229 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 167 1.5E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS26075 17feb2b2d28c17ab7be017d6d5e3f229 257 Gene3D G3DSA:3.40.50.720 4 219 2.0E-61 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS26075 17feb2b2d28c17ab7be017d6d5e3f229 257 Pfam PF00106 short chain dehydrogenase 5 188 6.7E-45 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS01180 a98d963297b6ecc5497eba428880db0a 521 Pfam PF01039 Carboxyl transferase domain 38 519 4.4E-130 T 06-07-2017 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 BWK49_RS01180 a98d963297b6ecc5497eba428880db0a 521 SUPERFAMILY SSF52096 227 513 7.77E-76 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS01180 a98d963297b6ecc5497eba428880db0a 521 SUPERFAMILY SSF52096 12 251 3.11E-64 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS01180 a98d963297b6ecc5497eba428880db0a 521 Gene3D G3DSA:3.90.226.10 16 248 8.8E-61 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS01180 a98d963297b6ecc5497eba428880db0a 521 Gene3D G3DSA:3.90.226.10 249 520 2.8E-76 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS11995 3e9e4658da38be6c9c6727123c2a2be7 644 Hamap MF_00505 Chaperone protein HtpG [htpG]. 3 641 30.096 T 06-07-2017 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 BWK49_RS11995 3e9e4658da38be6c9c6727123c2a2be7 644 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 31 160 4.9E-13 T 06-07-2017 BWK49_RS11995 3e9e4658da38be6c9c6727123c2a2be7 644 Gene3D G3DSA:3.30.565.10 6 253 8.1E-76 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS11995 3e9e4658da38be6c9c6727123c2a2be7 644 SUPERFAMILY SSF110942 524 640 2.88E-34 T 06-07-2017 BWK49_RS11995 3e9e4658da38be6c9c6727123c2a2be7 644 PRINTS PR00775 90kDa heat shock protein signature 76 93 1.9E-56 T 06-07-2017 IPR020575 Heat shock protein Hsp90, N-terminal BWK49_RS11995 3e9e4658da38be6c9c6727123c2a2be7 644 PRINTS PR00775 90kDa heat shock protein signature 199 217 1.9E-56 T 06-07-2017 IPR020575 Heat shock protein Hsp90, N-terminal BWK49_RS11995 3e9e4658da38be6c9c6727123c2a2be7 644 PRINTS PR00775 90kDa heat shock protein signature 126 148 1.9E-56 T 06-07-2017 IPR020575 Heat shock protein Hsp90, N-terminal BWK49_RS11995 3e9e4658da38be6c9c6727123c2a2be7 644 PRINTS PR00775 90kDa heat shock protein signature 176 193 1.9E-56 T 06-07-2017 IPR020575 Heat shock protein Hsp90, N-terminal BWK49_RS11995 3e9e4658da38be6c9c6727123c2a2be7 644 PRINTS PR00775 90kDa heat shock protein signature 6 26 1.9E-56 T 06-07-2017 IPR020575 Heat shock protein Hsp90, N-terminal BWK49_RS11995 3e9e4658da38be6c9c6727123c2a2be7 644 PRINTS PR00775 90kDa heat shock protein signature 27 49 1.9E-56 T 06-07-2017 IPR020575 Heat shock protein Hsp90, N-terminal BWK49_RS11995 3e9e4658da38be6c9c6727123c2a2be7 644 PRINTS PR00775 90kDa heat shock protein signature 94 111 1.9E-56 T 06-07-2017 IPR020575 Heat shock protein Hsp90, N-terminal BWK49_RS11995 3e9e4658da38be6c9c6727123c2a2be7 644 SMART SM00387 28 188 3.4E-5 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS11995 3e9e4658da38be6c9c6727123c2a2be7 644 Pfam PF00183 Hsp90 protein 234 641 8.2E-139 T 06-07-2017 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 BWK49_RS11995 3e9e4658da38be6c9c6727123c2a2be7 644 SUPERFAMILY SSF55874 5 223 1.96E-59 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS11995 3e9e4658da38be6c9c6727123c2a2be7 644 SUPERFAMILY SSF54211 246 499 9.1E-95 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold BWK49_RS11995 3e9e4658da38be6c9c6727123c2a2be7 644 PIRSF PIRSF002583 1 643 1.7E-224 T 06-07-2017 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 BWK49_RS06495 e57bb4b9125d1d88b6a3ae7b3aaf8df6 403 ProSitePatterns PS00099 Thiolases active site. 384 397 - T 06-07-2017 IPR020610 Thiolase, active site GO:0008152|GO:0016747 BWK49_RS06495 e57bb4b9125d1d88b6a3ae7b3aaf8df6 403 SUPERFAMILY SSF53901 2 274 1.01E-63 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS06495 e57bb4b9125d1d88b6a3ae7b3aaf8df6 403 Pfam PF02803 Thiolase, C-terminal domain 281 402 5.9E-47 T 06-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 BWK49_RS06495 e57bb4b9125d1d88b6a3ae7b3aaf8df6 403 Gene3D G3DSA:3.40.47.10 147 185 8.6E-58 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS06495 e57bb4b9125d1d88b6a3ae7b3aaf8df6 403 Gene3D G3DSA:3.40.47.10 287 402 8.6E-58 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS06495 e57bb4b9125d1d88b6a3ae7b3aaf8df6 403 Gene3D G3DSA:3.40.47.10 186 286 2.4E-56 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS06495 e57bb4b9125d1d88b6a3ae7b3aaf8df6 403 Gene3D G3DSA:3.40.47.10 5 127 2.4E-56 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS06495 e57bb4b9125d1d88b6a3ae7b3aaf8df6 403 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 7 401 3.3E-131 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 BWK49_RS06495 e57bb4b9125d1d88b6a3ae7b3aaf8df6 403 Pfam PF00108 Thiolase, N-terminal domain 6 229 1.4E-45 T 06-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 BWK49_RS06495 e57bb4b9125d1d88b6a3ae7b3aaf8df6 403 PIRSF PIRSF000429 1 403 6.3E-112 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 BWK49_RS06495 e57bb4b9125d1d88b6a3ae7b3aaf8df6 403 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 88 106 - T 06-07-2017 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 BWK49_RS06495 e57bb4b9125d1d88b6a3ae7b3aaf8df6 403 SUPERFAMILY SSF53901 281 402 9.49E-45 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS06495 e57bb4b9125d1d88b6a3ae7b3aaf8df6 403 ProSitePatterns PS00737 Thiolases signature 2. 349 365 - T 06-07-2017 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 BWK49_RS18375 f13932e9a2451daf87b22f7c6fbe90ec 235 Pfam PF00834 Ribulose-phosphate 3 epimerase family 16 210 5.1E-81 T 06-07-2017 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 BWK49_RS18375 f13932e9a2451daf87b22f7c6fbe90ec 235 PIRSF PIRSF001461 10 233 2.2E-95 T 06-07-2017 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 BWK49_RS18375 f13932e9a2451daf87b22f7c6fbe90ec 235 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 15 223 2.1E-84 T 06-07-2017 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 BWK49_RS18375 f13932e9a2451daf87b22f7c6fbe90ec 235 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 41 55 - T 06-07-2017 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 BWK49_RS18375 f13932e9a2451daf87b22f7c6fbe90ec 235 SUPERFAMILY SSF51366 15 225 8.75E-66 T 06-07-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 BWK49_RS18375 f13932e9a2451daf87b22f7c6fbe90ec 235 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 143 165 - T 06-07-2017 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 BWK49_RS18375 f13932e9a2451daf87b22f7c6fbe90ec 235 Gene3D G3DSA:3.20.20.70 13 228 1.4E-91 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 BWK49_RS22390 ee94c14848cf2989ee3ea5662bec7114 312 Gene3D G3DSA:3.40.50.170 1 202 3.7E-52 T 06-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 BWK49_RS22390 ee94c14848cf2989ee3ea5662bec7114 312 Pfam PF00551 Formyl transferase 1 175 2.5E-31 T 06-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 BWK49_RS22390 ee94c14848cf2989ee3ea5662bec7114 312 Gene3D G3DSA:3.10.25.10 206 303 5.6E-16 T 06-07-2017 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 BWK49_RS22390 ee94c14848cf2989ee3ea5662bec7114 312 SUPERFAMILY SSF50486 206 305 1.88E-16 T 06-07-2017 IPR011034 Formyl transferase, C-terminal-like GO:0003824 BWK49_RS22390 ee94c14848cf2989ee3ea5662bec7114 312 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 130 153 - T 06-07-2017 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 BWK49_RS22390 ee94c14848cf2989ee3ea5662bec7114 312 SUPERFAMILY SSF53328 1 203 2.35E-56 T 06-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 BWK49_RS22390 ee94c14848cf2989ee3ea5662bec7114 312 Pfam PF02911 Formyl transferase, C-terminal domain 204 303 7.3E-15 T 06-07-2017 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 BWK49_RS25265 e1f5e8fa3b795631ae5b3b05fbbc8dcf 459 SUPERFAMILY SSF69742 3 158 1.7E-42 T 06-07-2017 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 BWK49_RS25265 e1f5e8fa3b795631ae5b3b05fbbc8dcf 459 SUPERFAMILY SSF51735 163 317 3.77E-26 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS25265 e1f5e8fa3b795631ae5b3b05fbbc8dcf 459 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 172 316 1.9E-29 T 06-07-2017 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase BWK49_RS25265 e1f5e8fa3b795631ae5b3b05fbbc8dcf 459 Gene3D G3DSA:3.40.50.720 164 316 2.5E-30 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS25265 e1f5e8fa3b795631ae5b3b05fbbc8dcf 459 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 3 430 1.0E-151 T 06-07-2017 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 BWK49_RS25265 e1f5e8fa3b795631ae5b3b05fbbc8dcf 459 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 7 156 2.5E-43 T 06-07-2017 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 BWK49_RS25265 e1f5e8fa3b795631ae5b3b05fbbc8dcf 459 SUPERFAMILY SSF69075 329 430 1.7E-16 T 06-07-2017 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 BWK49_RS25265 e1f5e8fa3b795631ae5b3b05fbbc8dcf 459 PIRSF PIRSF000445 1 440 3.2E-139 T 06-07-2017 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 BWK49_RS25265 e1f5e8fa3b795631ae5b3b05fbbc8dcf 459 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 331 429 6.7E-21 T 06-07-2017 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 BWK49_RS25265 e1f5e8fa3b795631ae5b3b05fbbc8dcf 459 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 99 122 - T 06-07-2017 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 BWK49_RS25265 e1f5e8fa3b795631ae5b3b05fbbc8dcf 459 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 2 427 26.584 T 06-07-2017 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 BWK49_RS26185 97642e0fcb21e9ddcb09494350c54106 291 Pfam PF00483 Nucleotidyl transferase 3 236 2.8E-66 T 06-07-2017 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 BWK49_RS26185 97642e0fcb21e9ddcb09494350c54106 291 SUPERFAMILY SSF53448 1 286 5.83E-86 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases BWK49_RS26185 97642e0fcb21e9ddcb09494350c54106 291 Gene3D G3DSA:3.90.550.10 1 264 1.8E-65 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases BWK49_RS26185 97642e0fcb21e9ddcb09494350c54106 291 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 2 285 4.9E-149 T 06-07-2017 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688 BWK49_RS18205 c0d869dbb480930172001e7f6ea9eaee 699 SUPERFAMILY SSF52922 562 698 1.02E-38 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 BWK49_RS18205 c0d869dbb480930172001e7f6ea9eaee 699 SUPERFAMILY SSF52518 354 558 6.58E-61 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS18205 c0d869dbb480930172001e7f6ea9eaee 699 ProSitePatterns PS00802 Transketolase signature 2. 497 513 - T 06-07-2017 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 BWK49_RS18205 c0d869dbb480930172001e7f6ea9eaee 699 Pfam PF02780 Transketolase, C-terminal domain 582 689 1.2E-12 T 06-07-2017 IPR033248 Transketolase, C-terminal domain BWK49_RS18205 c0d869dbb480930172001e7f6ea9eaee 699 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 23 358 1.6E-142 T 06-07-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 BWK49_RS18205 c0d869dbb480930172001e7f6ea9eaee 699 SUPERFAMILY SSF52518 11 343 1.06E-99 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS18205 c0d869dbb480930172001e7f6ea9eaee 699 Pfam PF02779 Transketolase, pyrimidine binding domain 374 555 8.0E-45 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain BWK49_RS18205 c0d869dbb480930172001e7f6ea9eaee 699 ProSitePatterns PS00801 Transketolase signature 1. 31 51 - T 06-07-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 BWK49_RS18205 c0d869dbb480930172001e7f6ea9eaee 699 SMART SM00861 375 557 1.5E-61 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain BWK49_RS18205 c0d869dbb480930172001e7f6ea9eaee 699 Gene3D G3DSA:3.40.50.920 568 698 1.4E-45 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 BWK49_RS18205 c0d869dbb480930172001e7f6ea9eaee 699 Gene3D G3DSA:3.40.50.970 353 563 2.0E-70 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS18205 c0d869dbb480930172001e7f6ea9eaee 699 Gene3D G3DSA:3.40.50.970 17 344 2.0E-106 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS18205 c0d869dbb480930172001e7f6ea9eaee 699 TIGRFAM TIGR00232 tktlase_bact: transketolase 26 697 6.5E-232 T 06-07-2017 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 BWK49_RS02270 6b72aeedd398bd9827699a750a4b26b5 454 PIRSF PIRSF000337 2 452 3.7E-156 T 06-07-2017 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 BWK49_RS02270 6b72aeedd398bd9827699a750a4b26b5 454 Pfam PF00296 Luciferase-like monooxygenase 22 393 8.5E-58 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS02270 6b72aeedd398bd9827699a750a4b26b5 454 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 9 437 4.5E-158 T 06-07-2017 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 BWK49_RS02270 6b72aeedd398bd9827699a750a4b26b5 454 Gene3D G3DSA:3.20.20.30 2 315 5.5E-123 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS02270 6b72aeedd398bd9827699a750a4b26b5 454 Gene3D G3DSA:3.20.20.30 355 443 5.5E-123 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS02270 6b72aeedd398bd9827699a750a4b26b5 454 SUPERFAMILY SSF51679 4 443 5.5E-120 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS27770 7bc30f8166d5814905bef4dbfd81f9aa 476 Gene3D G3DSA:3.40.605.10 4 252 2.1E-79 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 BWK49_RS27770 7bc30f8166d5814905bef4dbfd81f9aa 476 Pfam PF00171 Aldehyde dehydrogenase family 13 467 9.1E-150 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 BWK49_RS27770 7bc30f8166d5814905bef4dbfd81f9aa 476 Gene3D G3DSA:3.40.309.10 253 443 1.0E-58 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 BWK49_RS27770 7bc30f8166d5814905bef4dbfd81f9aa 476 SUPERFAMILY SSF53720 3 468 8.25E-150 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 BWK49_RS23535 97ff982030b84d7b3324a8ce32bde76a 454 SMART SM00507 352 404 6.1E-5 T 06-07-2017 IPR003615 HNH nuclease BWK49_RS23535 97ff982030b84d7b3324a8ce32bde76a 454 Pfam PF02720 Domain of unknown function (DUF222) 38 361 2.0E-95 T 06-07-2017 IPR003870 Domain of unknown function DUF222 BWK49_RS23535 97ff982030b84d7b3324a8ce32bde76a 454 ProDom PD008243 RV1792C/MT1741/MB1728C RV1945/MT1995 MB1980 MB0098C RV3466/MT3572 VERY RV1128C/MT1160 RV1148C/MT1183 MB1159C RV0095C 8 92 1.0E-19 T 06-07-2017 BWK49_RS26740 72aa922f675d9a6cf697397a44b73a4e 57 Pfam PF11021 Protein of unknown function (DUF2613) 3 56 5.0E-22 T 06-07-2017 IPR022566 Protein of unknown function DUF2613 BWK49_RS26740 72aa922f675d9a6cf697397a44b73a4e 57 ProDom PD383784 PRECURSOR SIGNAL SECRETED MB0242C RV0236.1/MT0250 ML2569.1 3 56 2.0E-17 T 06-07-2017 BWK49_RS24360 7422fc4dbcd4bb4faf668df31f8242a1 397 SUPERFAMILY SSF51395 15 198 3.91E-83 T 06-07-2017 BWK49_RS24360 7422fc4dbcd4bb4faf668df31f8242a1 397 SUPERFAMILY SSF51395 228 380 3.91E-83 T 06-07-2017 BWK49_RS24360 7422fc4dbcd4bb4faf668df31f8242a1 397 Gene3D G3DSA:3.20.20.70 14 380 4.7E-116 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 BWK49_RS24360 7422fc4dbcd4bb4faf668df31f8242a1 397 PIRSF PIRSF000138 3 385 1.7E-106 T 06-07-2017 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 BWK49_RS24360 7422fc4dbcd4bb4faf668df31f8242a1 397 TIGRFAM TIGR03966 actino_HemFlav: heme/flavin dehydrogenase, mycofactocin system 5 388 9.0E-218 T 06-07-2017 IPR023989 Heme/flavin dehydrogenase, Rv0694 BWK49_RS24360 7422fc4dbcd4bb4faf668df31f8242a1 397 Pfam PF01070 FMN-dependent dehydrogenase 18 378 1.3E-109 T 06-07-2017 IPR000262 FMN-dependent dehydrogenase GO:0016491 BWK49_RS00755 c9efa06d79f27065fe36e6ceb522caf1 294 Pfam PF02353 Mycolic acid cyclopropane synthetase 11 289 1.5E-117 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS00755 c9efa06d79f27065fe36e6ceb522caf1 294 Gene3D G3DSA:3.40.50.150 12 293 1.5E-86 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS00755 c9efa06d79f27065fe36e6ceb522caf1 294 PIRSF PIRSF003085 3 294 3.3E-110 T 06-07-2017 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 BWK49_RS00755 c9efa06d79f27065fe36e6ceb522caf1 294 SUPERFAMILY SSF53335 19 293 2.37E-74 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS27280 c710a6efc419f349e4188c8534e02240 528 Gene3D G3DSA:2.30.38.10 349 420 2.5E-30 T 06-07-2017 BWK49_RS27280 c710a6efc419f349e4188c8534e02240 528 Gene3D G3DSA:3.40.50.980 21 186 2.8E-40 T 06-07-2017 BWK49_RS27280 c710a6efc419f349e4188c8534e02240 528 Gene3D G3DSA:3.40.50.980 187 348 1.1E-32 T 06-07-2017 BWK49_RS27280 c710a6efc419f349e4188c8534e02240 528 Pfam PF00501 AMP-binding enzyme 26 429 9.7E-104 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS27280 c710a6efc419f349e4188c8534e02240 528 ProSitePatterns PS00455 Putative AMP-binding domain signature. 181 192 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS27280 c710a6efc419f349e4188c8534e02240 528 Pfam PF13193 AMP-binding enzyme C-terminal domain 438 512 4.5E-17 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS27280 c710a6efc419f349e4188c8534e02240 528 SUPERFAMILY SSF56801 18 522 3.14E-150 T 06-07-2017 BWK49_RS27280 c710a6efc419f349e4188c8534e02240 528 Gene3D G3DSA:3.30.300.30 424 520 4.1E-28 T 06-07-2017 BWK49_RS28985 324cb720e327909aa980b65680e12781 98 Pfam PF06013 Proteins of 100 residues with WXG 5 90 8.4E-20 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like BWK49_RS28985 324cb720e327909aa980b65680e12781 98 Gene3D G3DSA:1.10.287.1060 1 97 3.4E-12 T 06-07-2017 BWK49_RS28985 324cb720e327909aa980b65680e12781 98 SUPERFAMILY SSF140453 4 97 1.96E-20 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like BWK49_RS28985 324cb720e327909aa980b65680e12781 98 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 5 93 2.0E-20 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like BWK49_RS25460 ac91b56871c1c82d86c36704028b823a 288 Gene3D G3DSA:3.40.50.150 8 287 1.1E-86 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS25460 ac91b56871c1c82d86c36704028b823a 288 PIRSF PIRSF003085 2 288 2.5E-114 T 06-07-2017 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 BWK49_RS25460 ac91b56871c1c82d86c36704028b823a 288 SUPERFAMILY SSF53335 13 287 5.31E-76 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS25460 ac91b56871c1c82d86c36704028b823a 288 Pfam PF02353 Mycolic acid cyclopropane synthetase 5 283 1.1E-117 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS12610 3d5c892efa842498f4e0ef1685c0f89a 281 PIRSF PIRSF000388 12 281 1.9E-115 T 06-07-2017 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 BWK49_RS12610 3d5c892efa842498f4e0ef1685c0f89a 281 SUPERFAMILY SSF51621 21 280 1.61E-101 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 BWK49_RS12610 3d5c892efa842498f4e0ef1685c0f89a 281 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 19 281 4.3E-94 T 06-07-2017 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 BWK49_RS12610 3d5c892efa842498f4e0ef1685c0f89a 281 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 21 281 42.528 T 06-07-2017 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 BWK49_RS12610 3d5c892efa842498f4e0ef1685c0f89a 281 Gene3D G3DSA:3.20.20.60 20 281 7.0E-112 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 BWK49_RS12610 3d5c892efa842498f4e0ef1685c0f89a 281 Pfam PF02548 Ketopantoate hydroxymethyltransferase 20 276 2.9E-108 T 06-07-2017 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 BWK49_RS07075 7ece2b615dd5e29bad8506f2d1bfde01 228 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 223 5.0E-25 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 BWK49_RS07075 7ece2b615dd5e29bad8506f2d1bfde01 228 Pfam PF00072 Response regulator receiver domain 3 112 1.2E-31 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 BWK49_RS07075 7ece2b615dd5e29bad8506f2d1bfde01 228 Gene3D G3DSA:1.10.10.10 126 225 6.6E-34 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS07075 7ece2b615dd5e29bad8506f2d1bfde01 228 SMART SM00448 1 112 1.9E-45 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 BWK49_RS07075 7ece2b615dd5e29bad8506f2d1bfde01 228 Gene3D G3DSA:3.40.50.2300 2 125 6.8E-44 T 06-07-2017 BWK49_RS07075 7ece2b615dd5e29bad8506f2d1bfde01 228 SUPERFAMILY SSF52172 2 182 3.42E-45 T 06-07-2017 IPR011006 CheY-like superfamily BWK49_RS07075 7ece2b615dd5e29bad8506f2d1bfde01 228 SMART SM00862 148 223 3.6E-26 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 BWK49_RS24285 c9d0629d83f3a8b663b2eeb7ffc3d1e5 77 ProSitePatterns PS00579 Ribosomal protein L29 signature. 43 57 - T 06-07-2017 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 BWK49_RS24285 c9d0629d83f3a8b663b2eeb7ffc3d1e5 77 TIGRFAM TIGR00012 L29: ribosomal protein uL29 9 64 1.6E-20 T 06-07-2017 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 BWK49_RS24285 c9d0629d83f3a8b663b2eeb7ffc3d1e5 77 Pfam PF00831 Ribosomal L29 protein 9 64 3.8E-24 T 06-07-2017 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 BWK49_RS24285 c9d0629d83f3a8b663b2eeb7ffc3d1e5 77 Gene3D G3DSA:1.10.287.310 8 68 6.0E-29 T 06-07-2017 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 BWK49_RS24285 c9d0629d83f3a8b663b2eeb7ffc3d1e5 77 SUPERFAMILY SSF46561 8 67 5.23E-22 T 06-07-2017 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 BWK49_RS24285 c9d0629d83f3a8b663b2eeb7ffc3d1e5 77 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 5 64 16.588 T 06-07-2017 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 BWK49_RS23245 8423354c23d1dbb8db5c0bb89f51bf10 411 SMART SM01150 13 371 2.3E-161 T 06-07-2017 IPR009770 Domain of unknown function DUF1338 BWK49_RS23245 8423354c23d1dbb8db5c0bb89f51bf10 411 Pfam PF07063 Domain of unknown function (DUF1338) 11 371 6.5E-98 T 06-07-2017 IPR009770 Domain of unknown function DUF1338 BWK49_RS02560 c93bf09fd2cf56250b85e979b798a4b6 437 Gene3D G3DSA:1.20.120.450 4 121 9.1E-4 T 06-07-2017 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase BWK49_RS02560 c93bf09fd2cf56250b85e979b798a4b6 437 SUPERFAMILY SSF109854 4 140 6.41E-18 T 06-07-2017 BWK49_RS02560 c93bf09fd2cf56250b85e979b798a4b6 437 Gene3D G3DSA:3.90.1580.10 173 434 1.0E-74 T 06-07-2017 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 BWK49_RS02560 c93bf09fd2cf56250b85e979b798a4b6 437 Pfam PF12867 DinB superfamily 13 144 4.9E-22 T 06-07-2017 IPR024775 DinB-like domain BWK49_RS02560 c93bf09fd2cf56250b85e979b798a4b6 437 Pfam PF03781 Sulfatase-modifying factor enzyme 1 173 429 1.1E-60 T 06-07-2017 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 BWK49_RS02560 c93bf09fd2cf56250b85e979b798a4b6 437 SUPERFAMILY SSF56436 175 432 5.65E-72 T 06-07-2017 IPR016187 C-type lectin fold BWK49_RS02560 c93bf09fd2cf56250b85e979b798a4b6 437 Hamap MF_02035 Hercynine oxygenase [egtB]. 1 432 47.828 T 06-07-2017 IPR032890 Hercynine oxygenase, Actinobacteria GO:0016491|GO:0052699 KEGG: 00340+1.14.99.50|MetaCyc: PWY-7255 BWK49_RS02560 c93bf09fd2cf56250b85e979b798a4b6 437 TIGRFAM TIGR03440 egtB_TIGR03440: ergothioneine biosynthesis protein EgtB 10 429 6.1E-130 T 06-07-2017 IPR017806 Ergothioneine biosynthesis protein EgtB GO:0052699 KEGG: 00340+1.14.99.50|MetaCyc: PWY-7255 BWK49_RS15415 05738a5160f0f393840f702faf6465a0 278 Gene3D G3DSA:2.30.30.50 181 278 9.3E-26 T 06-07-2017 BWK49_RS15415 05738a5160f0f393840f702faf6465a0 278 Pfam PF02211 Nitrile hydratase beta subunit 43 276 6.0E-58 T 06-07-2017 IPR024690 Nitrile hydratase beta subunit domain GO:0018822 KEGG: 00364+4.2.1.84|KEGG: 00380+4.2.1.84|KEGG: 00627+4.2.1.84|KEGG: 00643+4.2.1.84|MetaCyc: PWY-5025|MetaCyc: PWY-581|MetaCyc: PWY-7308 BWK49_RS15415 05738a5160f0f393840f702faf6465a0 278 SUPERFAMILY SSF50090 43 278 2.28E-54 T 06-07-2017 IPR008990 Electron transport accessory protein-like domain BWK49_RS15415 05738a5160f0f393840f702faf6465a0 278 Gene3D G3DSA:1.10.472.20 43 145 1.2E-33 T 06-07-2017 BWK49_RS24380 eca775491e58ae4fbf774f8dc6ec21e6 197 TIGRFAM TIGR03968 mycofact_TetR: mycofactocin system transcriptional regulator 5 192 1.0E-85 T 06-07-2017 IPR023851 Transcriptional regulator, TetR-type BWK49_RS24380 eca775491e58ae4fbf774f8dc6ec21e6 197 Gene3D G3DSA:1.10.357.10 58 191 5.3E-41 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS24380 eca775491e58ae4fbf774f8dc6ec21e6 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 59 3.8E-12 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS24380 eca775491e58ae4fbf774f8dc6ec21e6 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 1.0E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS24380 eca775491e58ae4fbf774f8dc6ec21e6 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 1.0E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS24380 eca775491e58ae4fbf774f8dc6ec21e6 197 Gene3D G3DSA:1.10.10.60 2 57 2.5E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS24380 eca775491e58ae4fbf774f8dc6ec21e6 197 SUPERFAMILY SSF46689 4 77 1.4E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS27860 2a6aa1c40c8a6d7ba30d845e37558d92 317 SUPERFAMILY SSF88946 13 80 2.28E-18 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS27860 2a6aa1c40c8a6d7ba30d845e37558d92 317 SUPERFAMILY SSF88659 124 182 1.18E-12 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS27860 2a6aa1c40c8a6d7ba30d845e37558d92 317 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 32 63 - T 06-07-2017 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS27860 2a6aa1c40c8a6d7ba30d845e37558d92 317 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 16 182 9.0E-22 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS27860 2a6aa1c40c8a6d7ba30d845e37558d92 317 TIGRFAM TIGR02960 SigX5: RNA polymerase sigma-70 factor, TIGR02960 family 4 313 5.2E-107 T 06-07-2017 IPR014305 RNA polymerase sigma-G type, actinobacteria BWK49_RS27860 2a6aa1c40c8a6d7ba30d845e37558d92 317 SUPERFAMILY SSF54427 197 309 3.97E-13 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS27860 2a6aa1c40c8a6d7ba30d845e37558d92 317 Gene3D G3DSA:1.10.10.10 124 183 2.2E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS27860 2a6aa1c40c8a6d7ba30d845e37558d92 317 Pfam PF04542 Sigma-70 region 2 14 77 1.9E-16 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS27860 2a6aa1c40c8a6d7ba30d845e37558d92 317 Gene3D G3DSA:3.10.450.50 195 312 3.7E-17 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS27860 2a6aa1c40c8a6d7ba30d845e37558d92 317 Pfam PF08281 Sigma-70, region 4 127 180 6.5E-15 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS27860 2a6aa1c40c8a6d7ba30d845e37558d92 317 Gene3D G3DSA:1.10.1740.10 4 85 2.1E-22 T 06-07-2017 BWK49_RS19080 3021d5b06af3f9a3e8a405455a6647a7 313 Pfam PF00199 Catalase 25 304 1.8E-28 T 06-07-2017 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 BWK49_RS19080 3021d5b06af3f9a3e8a405455a6647a7 313 Gene3D G3DSA:2.40.180.10 3 307 1.4E-86 T 06-07-2017 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 BWK49_RS19080 3021d5b06af3f9a3e8a405455a6647a7 313 PIRSF PIRSF000296 1 305 6.4E-93 T 06-07-2017 IPR024168 Catalase, SrpA-type, predicted BWK49_RS19080 3021d5b06af3f9a3e8a405455a6647a7 313 SUPERFAMILY SSF56634 5 303 6.54E-76 T 06-07-2017 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 BWK49_RS19080 3021d5b06af3f9a3e8a405455a6647a7 313 SMART SM01060 6 313 4.4E-7 T 06-07-2017 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 BWK49_RS19080 3021d5b06af3f9a3e8a405455a6647a7 313 PRINTS PR00067 Catalase signature 277 303 2.0E-9 T 06-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 BWK49_RS19080 3021d5b06af3f9a3e8a405455a6647a7 313 PRINTS PR00067 Catalase signature 55 73 2.0E-9 T 06-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 BWK49_RS19080 3021d5b06af3f9a3e8a405455a6647a7 313 PRINTS PR00067 Catalase signature 18 40 2.0E-9 T 06-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 BWK49_RS19080 3021d5b06af3f9a3e8a405455a6647a7 313 PRINTS PR00067 Catalase signature 76 93 2.0E-9 T 06-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 BWK49_RS17220 b66e40b2f92b6e166808d4d3f5735801 346 PIRSF PIRSF000267 2 339 2.2E-100 T 06-07-2017 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 BWK49_RS17220 b66e40b2f92b6e166808d4d3f5735801 346 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 3 219 1.8E-58 T 06-07-2017 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 BWK49_RS17220 b66e40b2f92b6e166808d4d3f5735801 346 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 3 326 3.2E-101 T 06-07-2017 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 BWK49_RS00100 7b7b21f78b4a905c65296077788227f0 228 Gene3D G3DSA:3.40.50.880 1 192 8.3E-64 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like BWK49_RS00100 7b7b21f78b4a905c65296077788227f0 228 PRINTS PR00096 Glutamine amidotransferase superfamily signature 168 181 3.7E-14 T 06-07-2017 BWK49_RS00100 7b7b21f78b4a905c65296077788227f0 228 PRINTS PR00096 Glutamine amidotransferase superfamily signature 50 59 3.7E-14 T 06-07-2017 BWK49_RS00100 7b7b21f78b4a905c65296077788227f0 228 PRINTS PR00096 Glutamine amidotransferase superfamily signature 78 89 3.7E-14 T 06-07-2017 BWK49_RS00100 7b7b21f78b4a905c65296077788227f0 228 Pfam PF00117 Glutamine amidotransferase class-I 5 189 8.9E-51 T 06-07-2017 IPR017926 Glutamine amidotransferase BWK49_RS00100 7b7b21f78b4a905c65296077788227f0 228 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 47 61 8.4E-10 T 06-07-2017 BWK49_RS00100 7b7b21f78b4a905c65296077788227f0 228 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 78 94 8.4E-10 T 06-07-2017 BWK49_RS00100 7b7b21f78b4a905c65296077788227f0 228 SUPERFAMILY SSF52317 1 192 2.07E-53 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like BWK49_RS00100 7b7b21f78b4a905c65296077788227f0 228 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 3 189 2.7E-61 T 06-07-2017 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 BWK49_RS00100 7b7b21f78b4a905c65296077788227f0 228 PRINTS PR00097 Anthranilate synthase component II signature 50 59 2.0E-35 T 06-07-2017 BWK49_RS00100 7b7b21f78b4a905c65296077788227f0 228 PRINTS PR00097 Anthranilate synthase component II signature 103 111 2.0E-35 T 06-07-2017 BWK49_RS00100 7b7b21f78b4a905c65296077788227f0 228 PRINTS PR00097 Anthranilate synthase component II signature 123 135 2.0E-35 T 06-07-2017 BWK49_RS00100 7b7b21f78b4a905c65296077788227f0 228 PRINTS PR00097 Anthranilate synthase component II signature 3 17 2.0E-35 T 06-07-2017 BWK49_RS00100 7b7b21f78b4a905c65296077788227f0 228 PRINTS PR00097 Anthranilate synthase component II signature 168 181 2.0E-35 T 06-07-2017 BWK49_RS00100 7b7b21f78b4a905c65296077788227f0 228 PRINTS PR00097 Anthranilate synthase component II signature 78 89 2.0E-35 T 06-07-2017 BWK49_RS05880 b786c10103b25e0ac9eed6074b24a077 247 Gene3D G3DSA:3.40.50.150 4 135 2.7E-14 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS05880 b786c10103b25e0ac9eed6074b24a077 247 Gene3D G3DSA:3.40.50.150 219 236 2.7E-14 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS05880 b786c10103b25e0ac9eed6074b24a077 247 SUPERFAMILY SSF53335 4 160 1.26E-13 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS05880 b786c10103b25e0ac9eed6074b24a077 247 Pfam PF08241 Methyltransferase domain 47 113 5.6E-7 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 BWK49_RS17125 a926fd536683904815754459a874d9b3 146 Pfam PF04167 Protein of unknown function (DUF402) 28 95 5.2E-16 T 06-07-2017 IPR007295 Domain of unknown function DUF402 BWK49_RS17125 a926fd536683904815754459a874d9b3 146 Gene3D G3DSA:2.40.380.10 1 140 1.3E-59 T 06-07-2017 IPR007295 Domain of unknown function DUF402 BWK49_RS17125 a926fd536683904815754459a874d9b3 146 PIRSF PIRSF012622 1 146 5.1E-72 T 06-07-2017 IPR014465 Uncharacterised conserved protein UCP012622 BWK49_RS17125 a926fd536683904815754459a874d9b3 146 SUPERFAMILY SSF159234 1 144 1.83E-46 T 06-07-2017 BWK49_RS02170 a05ac2b804cd70c146e817e661682f30 364 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 BWK49_RS02170 a05ac2b804cd70c146e817e661682f30 364 Gene3D G3DSA:3.10.580.10 275 359 5.7E-5 T 06-07-2017 BWK49_RS02170 a05ac2b804cd70c146e817e661682f30 364 Pfam PF00005 ABC transporter 19 163 3.3E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 BWK49_RS02170 a05ac2b804cd70c146e817e661682f30 364 SUPERFAMILY SSF52540 2 238 1.24E-70 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS02170 a05ac2b804cd70c146e817e661682f30 364 SUPERFAMILY SSF54631 275 357 3.84E-7 T 06-07-2017 BWK49_RS02170 a05ac2b804cd70c146e817e661682f30 364 Gene3D G3DSA:3.40.50.300 2 233 3.7E-71 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS02170 a05ac2b804cd70c146e817e661682f30 364 SMART SM00382 27 212 1.1E-16 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS12820 57980b18facd604874f2a04d94533f0f 368 ProSitePatterns PS00770 Aminotransferases class-IV signature. 240 273 - T 06-07-2017 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 BWK49_RS12820 57980b18facd604874f2a04d94533f0f 368 Pfam PF01063 Amino-transferase class IV 76 323 5.6E-34 T 06-07-2017 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 BWK49_RS12820 57980b18facd604874f2a04d94533f0f 368 TIGRFAM TIGR01123 ilvE_II: branched-chain amino acid aminotransferase 50 366 3.4E-144 T 06-07-2017 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|Reactome: R-HSA-70895 BWK49_RS12820 57980b18facd604874f2a04d94533f0f 368 SUPERFAMILY SSF56752 4 364 2.75E-113 T 06-07-2017 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 BWK49_RS12820 57980b18facd604874f2a04d94533f0f 368 PIRSF PIRSF006468 5 368 6.8E-132 T 06-07-2017 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|Reactome: R-HSA-70895 BWK49_RS12820 57980b18facd604874f2a04d94533f0f 368 Gene3D G3DSA:3.30.470.10 17 181 1.7E-67 T 06-07-2017 BWK49_RS12820 57980b18facd604874f2a04d94533f0f 368 Gene3D G3DSA:3.20.10.10 182 354 1.6E-67 T 06-07-2017 BWK49_RS19005 e65992c48908bb831bfbfad037034123 190 Pfam PF00775 Dioxygenase 35 175 7.1E-12 T 06-07-2017 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 BWK49_RS19005 e65992c48908bb831bfbfad037034123 190 TIGRFAM TIGR02423 protocat_alph: protocatechuate 3,4-dioxygenase, alpha subunit 7 184 1.6E-58 T 06-07-2017 IPR012786 Protocatechuate 3,4-dioxygenase, alpha subunit GO:0005506|GO:0018578|GO:0019439|GO:0055114 KEGG: 00362+1.13.11.3|KEGG: 00624+1.13.11.3 BWK49_RS19005 e65992c48908bb831bfbfad037034123 190 SUPERFAMILY SSF49482 3 183 1.7E-42 T 06-07-2017 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 BWK49_RS19005 e65992c48908bb831bfbfad037034123 190 Gene3D G3DSA:2.60.130.10 4 183 3.8E-63 T 06-07-2017 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 BWK49_RS07610 4c42279b59f9b740681fd9557c29bf1a 406 Pfam PF13847 Methyltransferase domain 57 156 1.6E-12 T 06-07-2017 IPR025714 Methyltransferase domain BWK49_RS07610 4c42279b59f9b740681fd9557c29bf1a 406 Gene3D G3DSA:3.40.50.150 197 301 3.1E-18 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS07610 4c42279b59f9b740681fd9557c29bf1a 406 Gene3D G3DSA:3.40.50.150 53 158 3.1E-18 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS07610 4c42279b59f9b740681fd9557c29bf1a 406 SUPERFAMILY SSF53335 14 183 4.06E-20 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS23650 2a67914740674843cb3e8b8437c2b2ba 419 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 262 376 6.2E-33 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal BWK49_RS23650 2a67914740674843cb3e8b8437c2b2ba 419 Gene3D G3DSA:3.40.47.10 15 267 1.0E-49 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS23650 2a67914740674843cb3e8b8437c2b2ba 419 SMART SM00825 Beta-ketoacyl synthase 13 410 3.2E-13 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain BWK49_RS23650 2a67914740674843cb3e8b8437c2b2ba 419 SUPERFAMILY SSF53901 222 419 8.65E-65 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS23650 2a67914740674843cb3e8b8437c2b2ba 419 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 12 254 6.5E-46 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal BWK49_RS23650 2a67914740674843cb3e8b8437c2b2ba 419 Gene3D G3DSA:3.40.47.10 271 419 2.7E-53 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS23650 2a67914740674843cb3e8b8437c2b2ba 419 SUPERFAMILY SSF53901 12 259 3.84E-50 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS13555 698147401aeb60aa46dd609823f1d924 1191 TIGRFAM TIGR02257 cobalto_cobN: cobaltochelatase, CobN subunit 46 1186 0.0 T 06-07-2017 IPR011953 Cobaltochelatase, CobN subunit GO:0009236|GO:0051116 BWK49_RS13555 698147401aeb60aa46dd609823f1d924 1191 Pfam PF02514 CobN/Magnesium Chelatase 104 1173 0.0 T 06-07-2017 IPR003672 CobN/magnesium chelatase GO:0009058 BWK49_RS23715 0bb9e9e5f0d80f05fc76cb98092ed07e 381 SUPERFAMILY SSF52540 78 131 1.52E-30 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS23715 0bb9e9e5f0d80f05fc76cb98092ed07e 381 SUPERFAMILY SSF52540 205 352 1.52E-30 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS23715 0bb9e9e5f0d80f05fc76cb98092ed07e 381 Pfam PF13469 Sulfotransferase family 83 331 1.8E-48 T 06-07-2017 BWK49_RS23715 0bb9e9e5f0d80f05fc76cb98092ed07e 381 Gene3D G3DSA:3.40.50.300 79 146 1.4E-9 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS23715 0bb9e9e5f0d80f05fc76cb98092ed07e 381 Gene3D G3DSA:3.40.50.300 215 336 1.4E-9 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS13935 a6ff526600488ef5624dbc4d4974852f 335 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 226 312 2.2E-13 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal BWK49_RS13935 a6ff526600488ef5624dbc4d4974852f 335 Gene3D G3DSA:3.40.50.300 3 199 9.7E-42 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS13935 a6ff526600488ef5624dbc4d4974852f 335 Gene3D G3DSA:3.30.1220.10 216 312 5.1E-10 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal BWK49_RS13935 a6ff526600488ef5624dbc4d4974852f 335 SMART SM00833 224 312 4.9E-12 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal BWK49_RS13935 a6ff526600488ef5624dbc4d4974852f 335 SUPERFAMILY SSF52540 4 202 5.58E-26 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS13935 a6ff526600488ef5624dbc4d4974852f 335 SUPERFAMILY SSF90002 232 312 5.1E-10 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal BWK49_RS13935 a6ff526600488ef5624dbc4d4974852f 335 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 5 176 6.8E-34 T 06-07-2017 IPR003495 CobW/HypB/UreG, nucleotide-binding domain BWK49_RS15385 85bbdc83c786fe4b04e1732b517916ec 78 Gene3D G3DSA:2.40.50.100 4 77 1.3E-11 T 06-07-2017 BWK49_RS15385 85bbdc83c786fe4b04e1732b517916ec 78 SUPERFAMILY SSF51230 4 77 8.64E-13 T 06-07-2017 IPR011053 Single hybrid motif BWK49_RS15385 85bbdc83c786fe4b04e1732b517916ec 78 Pfam PF00364 Biotin-requiring enzyme 6 74 1.3E-9 T 06-07-2017 IPR000089 Biotin/lipoyl attachment BWK49_RS15650 10d1ad2db8fa27adef664cb299fe8385 531 SUPERFAMILY SSF51905 312 528 1.52E-26 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS15650 10d1ad2db8fa27adef664cb299fe8385 531 SUPERFAMILY SSF51905 1 246 2.07E-52 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS15650 10d1ad2db8fa27adef664cb299fe8385 531 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 132 141 4.6E-9 T 06-07-2017 BWK49_RS15650 10d1ad2db8fa27adef664cb299fe8385 531 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 4.6E-9 T 06-07-2017 BWK49_RS15650 10d1ad2db8fa27adef664cb299fe8385 531 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 174 199 4.6E-9 T 06-07-2017 BWK49_RS15650 10d1ad2db8fa27adef664cb299fe8385 531 Gene3D G3DSA:3.50.50.60 357 524 5.0E-17 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS15650 10d1ad2db8fa27adef664cb299fe8385 531 Gene3D G3DSA:3.50.50.60 6 229 1.9E-57 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS15650 10d1ad2db8fa27adef664cb299fe8385 531 Pfam PF00743 Flavin-binding monooxygenase-like 7 207 2.9E-13 T 06-07-2017 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 BWK49_RS15650 10d1ad2db8fa27adef664cb299fe8385 531 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 8.9E-6 T 06-07-2017 BWK49_RS15650 10d1ad2db8fa27adef664cb299fe8385 531 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 174 192 8.9E-6 T 06-07-2017 BWK49_RS18055 20c6be88f9a721635c0d2cad1a152c5b 388 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 289 363 3.9E-11 T 06-07-2017 IPR022171 PPE family, C-terminal BWK49_RS18055 20c6be88f9a721635c0d2cad1a152c5b 388 SUPERFAMILY SSF140459 2 174 1.7E-62 T 06-07-2017 BWK49_RS18055 20c6be88f9a721635c0d2cad1a152c5b 388 Pfam PF00823 PPE family 6 161 3.0E-61 T 06-07-2017 IPR000030 PPE family BWK49_RS07545 f37dc590561afce3c35254496d028e89 851 Gene3D G3DSA:3.40.50.620 241 356 1.5E-16 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold BWK49_RS07545 f37dc590561afce3c35254496d028e89 851 SUPERFAMILY SSF55874 685 848 1.17E-33 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS07545 f37dc590561afce3c35254496d028e89 851 Gene3D G3DSA:1.10.287.130 621 680 4.8E-16 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 BWK49_RS07545 f37dc590561afce3c35254496d028e89 851 PRINTS PR00344 Bacterial sensor protein C-terminal signature 779 793 8.0E-9 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 BWK49_RS07545 f37dc590561afce3c35254496d028e89 851 PRINTS PR00344 Bacterial sensor protein C-terminal signature 797 807 8.0E-9 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 BWK49_RS07545 f37dc590561afce3c35254496d028e89 851 PRINTS PR00344 Bacterial sensor protein C-terminal signature 812 830 8.0E-9 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 BWK49_RS07545 f37dc590561afce3c35254496d028e89 851 SUPERFAMILY SSF52402 246 359 1.57E-15 T 06-07-2017 BWK49_RS07545 f37dc590561afce3c35254496d028e89 851 SMART SM00388 627 695 1.2E-14 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 BWK49_RS07545 f37dc590561afce3c35254496d028e89 851 Gene3D G3DSA:3.30.565.10 681 848 6.1E-34 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS07545 f37dc590561afce3c35254496d028e89 851 Pfam PF02702 Osmosensitive K+ channel His kinase sensor domain 16 225 1.8E-98 T 06-07-2017 IPR003852 Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal GO:0000155|GO:0000160|GO:0004673|GO:0016020 BWK49_RS07545 f37dc590561afce3c35254496d028e89 851 Pfam PF13493 Domain of unknown function (DUF4118) 391 498 2.0E-23 T 06-07-2017 IPR025201 Sensor protein KdpD, transmembrane domain BWK49_RS07545 f37dc590561afce3c35254496d028e89 851 Gene3D G3DSA:1.20.120.620 386 486 2.7E-17 T 06-07-2017 BWK49_RS07545 f37dc590561afce3c35254496d028e89 851 Pfam PF00582 Universal stress protein family 246 347 2.8E-9 T 06-07-2017 IPR006016 UspA GO:0006950 BWK49_RS07545 f37dc590561afce3c35254496d028e89 851 Pfam PF00512 His Kinase A (phospho-acceptor) domain 628 695 2.9E-12 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 BWK49_RS07545 f37dc590561afce3c35254496d028e89 851 SMART SM00387 743 850 1.5E-24 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS07545 f37dc590561afce3c35254496d028e89 851 SUPERFAMILY SSF47384 618 695 2.16E-13 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 BWK49_RS07545 f37dc590561afce3c35254496d028e89 851 Gene3D G3DSA:3.40.50.300 16 224 5.6E-99 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS07545 f37dc590561afce3c35254496d028e89 851 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 744 848 1.0E-19 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS24260 842cb09940db4cc453ca06f4fb7503d8 122 SUPERFAMILY SSF50193 2 122 7.72E-50 T 06-07-2017 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 BWK49_RS24260 842cb09940db4cc453ca06f4fb7503d8 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 8.3E-57 T 06-07-2017 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 BWK49_RS24260 842cb09940db4cc453ca06f4fb7503d8 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 26.794 T 06-07-2017 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 BWK49_RS24260 842cb09940db4cc453ca06f4fb7503d8 122 Gene3D G3DSA:2.40.150.20 2 122 7.4E-53 T 06-07-2017 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 BWK49_RS24260 842cb09940db4cc453ca06f4fb7503d8 122 Pfam PF00238 Ribosomal protein L14p/L23e 2 122 1.3E-53 T 06-07-2017 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 BWK49_RS24260 842cb09940db4cc453ca06f4fb7503d8 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 06-07-2017 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 BWK49_RS24260 842cb09940db4cc453ca06f4fb7503d8 122 SMART SM01374 1 122 3.1E-86 T 06-07-2017 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 BWK49_RS14885 36ade028d3c24659a7eb50cff8ab9313 410 Pfam PF14759 Reductase C-terminal 324 409 7.5E-14 T 06-07-2017 IPR028202 Reductase, C-terminal BWK49_RS14885 36ade028d3c24659a7eb50cff8ab9313 410 SUPERFAMILY SSF51905 3 187 5.44E-46 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS14885 36ade028d3c24659a7eb50cff8ab9313 410 SUPERFAMILY SSF55424 318 409 1.0E-25 T 06-07-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 BWK49_RS14885 36ade028d3c24659a7eb50cff8ab9313 410 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 103 121 4.8E-25 T 06-07-2017 BWK49_RS14885 36ade028d3c24659a7eb50cff8ab9313 410 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 234 250 4.8E-25 T 06-07-2017 BWK49_RS14885 36ade028d3c24659a7eb50cff8ab9313 410 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 148 166 4.8E-25 T 06-07-2017 BWK49_RS14885 36ade028d3c24659a7eb50cff8ab9313 410 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 4.8E-25 T 06-07-2017 BWK49_RS14885 36ade028d3c24659a7eb50cff8ab9313 410 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 260 282 4.8E-25 T 06-07-2017 BWK49_RS14885 36ade028d3c24659a7eb50cff8ab9313 410 Gene3D G3DSA:3.30.390.30 324 409 1.9E-28 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 BWK49_RS14885 36ade028d3c24659a7eb50cff8ab9313 410 Gene3D G3DSA:3.50.50.60 5 110 2.4E-27 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS14885 36ade028d3c24659a7eb50cff8ab9313 410 SUPERFAMILY SSF51905 147 314 1.43E-32 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS14885 36ade028d3c24659a7eb50cff8ab9313 410 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 3.3E-15 T 06-07-2017 BWK49_RS14885 36ade028d3c24659a7eb50cff8ab9313 410 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 148 173 3.3E-15 T 06-07-2017 BWK49_RS14885 36ade028d3c24659a7eb50cff8ab9313 410 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 235 249 3.3E-15 T 06-07-2017 BWK49_RS14885 36ade028d3c24659a7eb50cff8ab9313 410 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 275 282 3.3E-15 T 06-07-2017 BWK49_RS14885 36ade028d3c24659a7eb50cff8ab9313 410 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 304 1.5E-61 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS14885 36ade028d3c24659a7eb50cff8ab9313 410 Gene3D G3DSA:3.50.50.60 111 314 7.5E-52 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS18245 ed758ba383011396d0412875034b41e2 938 Gene3D G3DSA:1.20.1440.90 300 423 2.5E-23 T 06-07-2017 BWK49_RS18245 ed758ba383011396d0412875034b41e2 938 ProSitePatterns PS00781 Phosphoenolpyruvate carboxylase active site 1. 160 171 - T 06-07-2017 IPR018129 Phosphoenolpyruvate carboxylase, Lys active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 BWK49_RS18245 ed758ba383011396d0412875034b41e2 938 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 271 286 1.3E-55 T 06-07-2017 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 BWK49_RS18245 ed758ba383011396d0412875034b41e2 938 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 420 440 1.3E-55 T 06-07-2017 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 BWK49_RS18245 ed758ba383011396d0412875034b41e2 938 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 585 605 1.3E-55 T 06-07-2017 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 BWK49_RS18245 ed758ba383011396d0412875034b41e2 938 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 212 228 1.3E-55 T 06-07-2017 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 BWK49_RS18245 ed758ba383011396d0412875034b41e2 938 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 159 172 1.3E-55 T 06-07-2017 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 BWK49_RS18245 ed758ba383011396d0412875034b41e2 938 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 762 788 1.3E-55 T 06-07-2017 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 BWK49_RS18245 ed758ba383011396d0412875034b41e2 938 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 627 656 1.3E-55 T 06-07-2017 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 BWK49_RS18245 ed758ba383011396d0412875034b41e2 938 ProSitePatterns PS00393 Phosphoenolpyruvate carboxylase active site 2. 587 599 - T 06-07-2017 IPR033129 Phosphoenolpyruvate carboxylase, His active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 BWK49_RS18245 ed758ba383011396d0412875034b41e2 938 Pfam PF00311 Phosphoenolpyruvate carboxylase 157 938 2.3E-263 T 06-07-2017 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 BWK49_RS18245 ed758ba383011396d0412875034b41e2 938 SUPERFAMILY SSF51621 32 938 2.67E-288 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 BWK49_RS18245 ed758ba383011396d0412875034b41e2 938 Hamap MF_00595 Phosphoenolpyruvate carboxylase [ppc]. 24 938 19.13 T 06-07-2017 IPR022805 Phosphoenolpyruvate carboxylase, bacterial/plant-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 BWK49_RS01110 b156ae32a17bcd042bc7237fa03522ff 261 Gene3D G3DSA:3.40.1130.10 5 207 1.6E-16 T 06-07-2017 BWK49_RS01110 b156ae32a17bcd042bc7237fa03522ff 261 SMART SM00563 38 152 3.6E-31 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 BWK49_RS01110 b156ae32a17bcd042bc7237fa03522ff 261 SUPERFAMILY SSF69593 6 208 4.84E-32 T 06-07-2017 BWK49_RS01110 b156ae32a17bcd042bc7237fa03522ff 261 Pfam PF01553 Acyltransferase 24 149 1.1E-28 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 BWK49_RS18790 7109e0875a84b6935945dad839aa6134 429 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 45 347 23.283 T 06-07-2017 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 BWK49_RS18790 7109e0875a84b6935945dad839aa6134 429 SUPERFAMILY SSF82866 139 346 4.19E-26 T 06-07-2017 BWK49_RS18790 7109e0875a84b6935945dad839aa6134 429 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 110 333 2.2E-51 T 06-07-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial BWK49_RS18790 7109e0875a84b6935945dad839aa6134 429 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 73 336 1.3E-77 T 06-07-2017 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 BWK49_RS18790 7109e0875a84b6935945dad839aa6134 429 PRINTS PR01755 Bacterial translocase SecF protein signature 244 262 2.8E-22 T 06-07-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial BWK49_RS18790 7109e0875a84b6935945dad839aa6134 429 PRINTS PR01755 Bacterial translocase SecF protein signature 72 87 2.8E-22 T 06-07-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial BWK49_RS18790 7109e0875a84b6935945dad839aa6134 429 PRINTS PR01755 Bacterial translocase SecF protein signature 196 210 2.8E-22 T 06-07-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial BWK49_RS18790 7109e0875a84b6935945dad839aa6134 429 PRINTS PR01755 Bacterial translocase SecF protein signature 279 294 2.8E-22 T 06-07-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial BWK49_RS18790 7109e0875a84b6935945dad839aa6134 429 Pfam PF02355 Protein export membrane protein 159 345 6.9E-63 T 06-07-2017 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial BWK49_RS18790 7109e0875a84b6935945dad839aa6134 429 Gene3D G3DSA:1.20.1640.10 176 348 6.8E-16 T 06-07-2017 BWK49_RS04170 59a84e6624e1300a65606f633a9d4593 340 PIRSF PIRSF000346 1 325 7.2E-112 T 06-07-2017 IPR005067 Fatty acid desaturase, type 2 GO:0006631|GO:0045300|GO:0055114 BWK49_RS04170 59a84e6624e1300a65606f633a9d4593 340 SUPERFAMILY SSF47240 1 311 2.78E-88 T 06-07-2017 IPR009078 Ferritin-like superfamily BWK49_RS04170 59a84e6624e1300a65606f633a9d4593 340 Pfam PF03405 Fatty acid desaturase 7 316 3.0E-89 T 06-07-2017 IPR005067 Fatty acid desaturase, type 2 GO:0006631|GO:0045300|GO:0055114 BWK49_RS04170 59a84e6624e1300a65606f633a9d4593 340 Gene3D G3DSA:1.10.620.20 1 312 1.1E-110 T 06-07-2017 IPR012348 Ribonucleotide reductase-related GO:0016491|GO:0055114 Reactome: R-HSA-499943 BWK49_RS26255 793b4ddc5c1936bd30506f2d23e6baa0 268 Gene3D G3DSA:2.40.440.10 164 267 3.5E-18 T 06-07-2017 BWK49_RS26255 793b4ddc5c1936bd30506f2d23e6baa0 268 Pfam PF03734 L,D-transpeptidase catalytic domain 164 266 3.3E-14 T 06-07-2017 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 BWK49_RS26255 793b4ddc5c1936bd30506f2d23e6baa0 268 SUPERFAMILY SSF141523 163 266 4.05E-26 T 06-07-2017 BWK49_RS13070 ce5f60bac2a0f2e7ad224f00584f5675 515 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 4 505 30.296 T 06-07-2017 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 BWK49_RS13070 ce5f60bac2a0f2e7ad224f00584f5675 515 Pfam PF08245 Mur ligase middle domain 134 330 4.4E-39 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 BWK49_RS13070 ce5f60bac2a0f2e7ad224f00584f5675 515 Gene3D G3DSA:3.40.1390.10 1 84 6.5E-21 T 06-07-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 BWK49_RS13070 ce5f60bac2a0f2e7ad224f00584f5675 515 SUPERFAMILY SSF63418 2 86 2.49E-16 T 06-07-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 BWK49_RS13070 ce5f60bac2a0f2e7ad224f00584f5675 515 Gene3D G3DSA:3.90.190.20 351 506 9.4E-41 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 BWK49_RS13070 ce5f60bac2a0f2e7ad224f00584f5675 515 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 36 504 6.9E-129 T 06-07-2017 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 BWK49_RS13070 ce5f60bac2a0f2e7ad224f00584f5675 515 Gene3D G3DSA:3.40.1190.10 109 345 2.7E-60 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 BWK49_RS13070 ce5f60bac2a0f2e7ad224f00584f5675 515 Pfam PF01225 Mur ligase family, catalytic domain 34 80 6.0E-9 T 06-07-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 BWK49_RS13070 ce5f60bac2a0f2e7ad224f00584f5675 515 SUPERFAMILY SSF53244 352 504 1.83E-29 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 BWK49_RS13070 ce5f60bac2a0f2e7ad224f00584f5675 515 Pfam PF02875 Mur ligase family, glutamate ligase domain 352 442 8.9E-27 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 BWK49_RS13070 ce5f60bac2a0f2e7ad224f00584f5675 515 SUPERFAMILY SSF53623 129 347 1.44E-48 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 BWK49_RS13090 9e409104f808653bfddf7773bed15da6 407 Gene3D G3DSA:3.40.50.2000 29 221 8.5E-60 T 06-07-2017 BWK49_RS13090 9e409104f808653bfddf7773bed15da6 407 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 31 393 30.925 T 06-07-2017 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 BWK49_RS13090 9e409104f808653bfddf7773bed15da6 407 SUPERFAMILY SSF53756 31 394 2.13E-95 T 06-07-2017 BWK49_RS13090 9e409104f808653bfddf7773bed15da6 407 Gene3D G3DSA:3.40.50.2000 222 387 1.3E-17 T 06-07-2017 BWK49_RS13090 9e409104f808653bfddf7773bed15da6 407 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 30 388 1.5E-86 T 06-07-2017 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 BWK49_RS13090 9e409104f808653bfddf7773bed15da6 407 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 31 177 2.7E-38 T 06-07-2017 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 BWK49_RS13090 9e409104f808653bfddf7773bed15da6 407 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 223 384 4.3E-39 T 06-07-2017 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 BWK49_RS05030 728430c0a082b50b7aced96e92795c71 821 Pfam PF00589 Phage integrase family 488 673 1.4E-13 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 BWK49_RS05030 728430c0a082b50b7aced96e92795c71 821 SUPERFAMILY SSF56349 490 677 2.85E-20 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 BWK49_RS05030 728430c0a082b50b7aced96e92795c71 821 Gene3D G3DSA:1.10.443.10 485 677 3.7E-21 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 BWK49_RS22490 728430c0a082b50b7aced96e92795c71 821 Pfam PF00589 Phage integrase family 488 673 1.4E-13 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 BWK49_RS22490 728430c0a082b50b7aced96e92795c71 821 SUPERFAMILY SSF56349 490 677 2.85E-20 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 BWK49_RS22490 728430c0a082b50b7aced96e92795c71 821 Gene3D G3DSA:1.10.443.10 485 677 3.7E-21 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 BWK49_RS10505 728430c0a082b50b7aced96e92795c71 821 Pfam PF00589 Phage integrase family 488 673 1.4E-13 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 BWK49_RS10505 728430c0a082b50b7aced96e92795c71 821 SUPERFAMILY SSF56349 490 677 2.85E-20 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 BWK49_RS10505 728430c0a082b50b7aced96e92795c71 821 Gene3D G3DSA:1.10.443.10 485 677 3.7E-21 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 BWK49_RS10380 728430c0a082b50b7aced96e92795c71 821 Pfam PF00589 Phage integrase family 488 673 1.4E-13 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 BWK49_RS10380 728430c0a082b50b7aced96e92795c71 821 SUPERFAMILY SSF56349 490 677 2.85E-20 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 BWK49_RS10380 728430c0a082b50b7aced96e92795c71 821 Gene3D G3DSA:1.10.443.10 485 677 3.7E-21 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 BWK49_RS26935 c439778f3935427e1d492a66b286a1fc 256 SUPERFAMILY SSF53335 49 211 4.66E-28 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS26935 c439778f3935427e1d492a66b286a1fc 256 Gene3D G3DSA:3.40.50.150 49 161 4.0E-25 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS26935 c439778f3935427e1d492a66b286a1fc 256 Pfam PF08241 Methyltransferase domain 63 155 5.5E-17 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 BWK49_RS22155 90859e0b570e7d125f37099b2a1b6943 192 SUPERFAMILY SSF81301 16 149 7.52E-26 T 06-07-2017 BWK49_RS22155 90859e0b570e7d125f37099b2a1b6943 192 Pfam PF14907 Uncharacterised nucleotidyltransferase 41 175 1.4E-7 T 06-07-2017 BWK49_RS12090 36c66fc0b164bb09ae9508e32c7b5117 353 Gene3D G3DSA:3.40.50.720 1 206 2.5E-25 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS12090 36c66fc0b164bb09ae9508e32c7b5117 353 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 2 71 1.4E-6 T 06-07-2017 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 BWK49_RS12090 36c66fc0b164bb09ae9508e32c7b5117 353 SUPERFAMILY SSF51735 1 152 2.19E-15 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS14160 9e264da5d3eddab6ebb6bfc5434a289e 320 Gene3D G3DSA:3.40.190.10 90 178 5.3E-18 T 06-07-2017 BWK49_RS14160 9e264da5d3eddab6ebb6bfc5434a289e 320 Gene3D G3DSA:3.40.190.10 179 264 1.2E-22 T 06-07-2017 BWK49_RS14160 9e264da5d3eddab6ebb6bfc5434a289e 320 SUPERFAMILY SSF53850 90 300 1.96E-38 T 06-07-2017 BWK49_RS14160 9e264da5d3eddab6ebb6bfc5434a289e 320 SUPERFAMILY SSF46785 2 86 2.08E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS14160 9e264da5d3eddab6ebb6bfc5434a289e 320 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 6.1E-20 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 BWK49_RS14160 9e264da5d3eddab6ebb6bfc5434a289e 320 Pfam PF03466 LysR substrate binding domain 89 294 5.8E-41 T 06-07-2017 IPR005119 LysR, substrate-binding BWK49_RS14160 9e264da5d3eddab6ebb6bfc5434a289e 320 Gene3D G3DSA:1.10.10.10 2 86 5.3E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS20235 51ec8c29e1df77497a6d221fe412d663 503 Pfam PF01078 Magnesium chelatase, subunit ChlI 190 393 3.2E-83 T 06-07-2017 IPR000523 Magnesium chelatase ChlI domain BWK49_RS20235 51ec8c29e1df77497a6d221fe412d663 503 Pfam PF13541 Subunit ChlI of Mg-chelatase 21 143 3.7E-38 T 06-07-2017 BWK49_RS20235 51ec8c29e1df77497a6d221fe412d663 503 TIGRFAM TIGR00368 TIGR00368: Mg chelatase-like protein 7 497 1.1E-139 T 06-07-2017 IPR004482 Mg chelatase-related protein BWK49_RS20235 51ec8c29e1df77497a6d221fe412d663 503 Pfam PF13335 Magnesium chelatase, subunit ChlI C-terminal 401 497 1.4E-24 T 06-07-2017 IPR025158 Mg chelatase-related protein, C-terminal domain BWK49_RS20235 51ec8c29e1df77497a6d221fe412d663 503 SMART SM00382 210 392 5.7E-8 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS20235 51ec8c29e1df77497a6d221fe412d663 503 SUPERFAMILY SSF52540 187 499 3.68E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS20235 51ec8c29e1df77497a6d221fe412d663 503 Gene3D G3DSA:3.40.50.300 189 387 5.5E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS20235 51ec8c29e1df77497a6d221fe412d663 503 Gene3D G3DSA:3.30.230.10 3 168 7.0E-40 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup BWK49_RS20235 51ec8c29e1df77497a6d221fe412d663 503 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 3 19 1.1E-5 T 06-07-2017 BWK49_RS20235 51ec8c29e1df77497a6d221fe412d663 503 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 106 125 1.1E-5 T 06-07-2017 BWK49_RS20235 51ec8c29e1df77497a6d221fe412d663 503 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 129 147 1.1E-5 T 06-07-2017 BWK49_RS20235 51ec8c29e1df77497a6d221fe412d663 503 SUPERFAMILY SSF54211 3 168 2.16E-37 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold BWK49_RS16930 edcc995e18cf61e4f1d682ccd3d89620 2129 Gene3D G3DSA:3.40.47.10 297 462 6.0E-63 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS16930 edcc995e18cf61e4f1d682ccd3d89620 2129 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2001 2016 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site BWK49_RS16930 edcc995e18cf61e4f1d682ccd3d89620 2129 SMART SM01294 1975 2042 6.8E-5 T 06-07-2017 BWK49_RS16930 edcc995e18cf61e4f1d682ccd3d89620 2129 SUPERFAMILY SSF51735 1462 1597 2.09E-35 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS16930 edcc995e18cf61e4f1d682ccd3d89620 2129 SUPERFAMILY SSF50129 1368 1496 2.74E-24 T 06-07-2017 IPR011032 GroES-like BWK49_RS16930 edcc995e18cf61e4f1d682ccd3d89620 2129 SUPERFAMILY SSF55048 688 753 5.23E-10 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 BWK49_RS16930 edcc995e18cf61e4f1d682ccd3d89620 2129 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 565 861 1.1E-115 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain BWK49_RS16930 edcc995e18cf61e4f1d682ccd3d89620 2129 Gene3D G3DSA:3.40.47.10 37 296 4.1E-91 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS16930 edcc995e18cf61e4f1d682ccd3d89620 2129 SUPERFAMILY SSF51735 1686 1939 2.46E-45 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS16930 edcc995e18cf61e4f1d682ccd3d89620 2129 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 35 284 3.9E-89 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal BWK49_RS16930 edcc995e18cf61e4f1d682ccd3d89620 2129 Gene3D G3DSA:3.40.50.720 1686 1871 1.9E-37 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS16930 edcc995e18cf61e4f1d682ccd3d89620 2129 SUPERFAMILY SSF53901 31 407 8.96E-101 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS16930 edcc995e18cf61e4f1d682ccd3d89620 2129 SMART SM00825 Beta-ketoacyl synthase 37 462 9.2E-212 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain BWK49_RS16930 edcc995e18cf61e4f1d682ccd3d89620 2129 SUPERFAMILY SSF47336 1966 2053 5.37E-21 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS16930 edcc995e18cf61e4f1d682ccd3d89620 2129 SMART SM00829 1367 1669 2.9E-166 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 BWK49_RS16930 edcc995e18cf61e4f1d682ccd3d89620 2129 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1689 1869 1.2E-56 T 06-07-2017 BWK49_RS16930 edcc995e18cf61e4f1d682ccd3d89620 2129 Pfam PF13602 Zinc-binding dehydrogenase 1538 1669 5.4E-19 T 06-07-2017 BWK49_RS16930 edcc995e18cf61e4f1d682ccd3d89620 2129 Pfam PF14765 Polyketide synthase dehydratase 929 1198 6.8E-55 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS16930 edcc995e18cf61e4f1d682ccd3d89620 2129 SUPERFAMILY SSF51735 1145 1347 2.23E-22 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS16930 edcc995e18cf61e4f1d682ccd3d89620 2129 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 1385 1439 2.9E-5 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 BWK49_RS16930 edcc995e18cf61e4f1d682ccd3d89620 2129 Pfam PF00550 Phosphopantetheine attachment site 1977 2042 5.2E-11 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS16930 edcc995e18cf61e4f1d682ccd3d89620 2129 Gene3D G3DSA:3.30.70.250 690 752 1.5E-4 T 06-07-2017 BWK49_RS16930 edcc995e18cf61e4f1d682ccd3d89620 2129 SMART SM00823 Phosphopantetheine attachment site 1974 2046 8.4E-28 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS16930 edcc995e18cf61e4f1d682ccd3d89620 2129 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 292 409 9.4E-41 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal BWK49_RS16930 edcc995e18cf61e4f1d682ccd3d89620 2129 Gene3D G3DSA:3.40.50.720 1454 1646 2.5E-43 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS16930 edcc995e18cf61e4f1d682ccd3d89620 2129 Gene3D G3DSA:3.40.366.10 753 861 8.3E-74 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 BWK49_RS16930 edcc995e18cf61e4f1d682ccd3d89620 2129 Gene3D G3DSA:3.40.366.10 561 684 8.3E-74 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 BWK49_RS16930 edcc995e18cf61e4f1d682ccd3d89620 2129 SMART SM00826 929 1090 3.7E-76 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS16930 edcc995e18cf61e4f1d682ccd3d89620 2129 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 197 213 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site BWK49_RS16930 edcc995e18cf61e4f1d682ccd3d89620 2129 SUPERFAMILY SSF52151 754 848 2.3E-68 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 BWK49_RS16930 edcc995e18cf61e4f1d682ccd3d89620 2129 SUPERFAMILY SSF52151 561 690 2.3E-68 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 BWK49_RS16930 edcc995e18cf61e4f1d682ccd3d89620 2129 Pfam PF08659 KR domain 1689 1867 6.3E-59 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS16930 edcc995e18cf61e4f1d682ccd3d89620 2129 Gene3D G3DSA:3.90.180.10 1371 1442 1.5E-10 T 06-07-2017 IPR011032 GroES-like BWK49_RS16930 edcc995e18cf61e4f1d682ccd3d89620 2129 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 412 528 7.2E-17 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS16930 edcc995e18cf61e4f1d682ccd3d89620 2129 Gene3D G3DSA:1.10.1200.10 1970 2048 7.4E-23 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS16930 edcc995e18cf61e4f1d682ccd3d89620 2129 Pfam PF00698 Acyl transferase domain 563 879 4.7E-89 T 06-07-2017 IPR014043 Acyl transferase BWK49_RS01035 e8f44a5517e1f780a766084c98e7003b 316 Pfam PF01842 ACT domain 204 267 4.1E-9 T 06-07-2017 IPR002912 ACT domain GO:0008152|GO:0016597 BWK49_RS01035 e8f44a5517e1f780a766084c98e7003b 316 Gene3D G3DSA:3.30.70.260 196 281 7.7E-31 T 06-07-2017 BWK49_RS01035 e8f44a5517e1f780a766084c98e7003b 316 SUPERFAMILY SSF53850 3 195 1.67E-44 T 06-07-2017 BWK49_RS01035 e8f44a5517e1f780a766084c98e7003b 316 ProSitePatterns PS00858 Prephenate dehydratase signature 2. 229 236 - T 06-07-2017 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 BWK49_RS01035 e8f44a5517e1f780a766084c98e7003b 316 Pfam PF00800 Prephenate dehydratase 4 188 4.5E-43 T 06-07-2017 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 BWK49_RS01035 e8f44a5517e1f780a766084c98e7003b 316 PIRSF PIRSF001500 1 283 3.3E-60 T 06-07-2017 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 BWK49_RS01035 e8f44a5517e1f780a766084c98e7003b 316 Gene3D G3DSA:3.40.190.10 3 99 3.6E-26 T 06-07-2017 BWK49_RS01035 e8f44a5517e1f780a766084c98e7003b 316 Gene3D G3DSA:3.40.190.10 100 177 1.1E-13 T 06-07-2017 BWK49_RS01035 e8f44a5517e1f780a766084c98e7003b 316 SUPERFAMILY SSF55021 185 281 4.5E-25 T 06-07-2017 BWK49_RS06535 113d03fb5855bfc39918e25fc9989d88 310 Pfam PF12833 Helix-turn-helix domain 229 306 4.1E-17 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 BWK49_RS06535 113d03fb5855bfc39918e25fc9989d88 310 SUPERFAMILY SSF46689 208 256 1.84E-8 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS06535 113d03fb5855bfc39918e25fc9989d88 310 Gene3D G3DSA:1.10.10.60 261 307 5.3E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS06535 113d03fb5855bfc39918e25fc9989d88 310 Gene3D G3DSA:1.10.10.60 205 260 4.6E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS06535 113d03fb5855bfc39918e25fc9989d88 310 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 260 302 - T 06-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 BWK49_RS06535 113d03fb5855bfc39918e25fc9989d88 310 SUPERFAMILY SSF46689 259 307 1.57E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS06535 113d03fb5855bfc39918e25fc9989d88 310 Pfam PF12852 Cupin 2 192 4.7E-44 T 06-07-2017 IPR032783 AraC-type transcription regulator, ligand-binding domain BWK49_RS06535 113d03fb5855bfc39918e25fc9989d88 310 SMART SM00342 223 306 9.8E-27 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 BWK49_RS24610 5650d6582f69df59b50f0a99287a90be 142 Gene3D G3DSA:3.10.129.10 4 132 3.2E-35 T 06-07-2017 IPR029069 HotDog domain BWK49_RS24610 5650d6582f69df59b50f0a99287a90be 142 SUPERFAMILY SSF54637 6 132 6.22E-25 T 06-07-2017 IPR029069 HotDog domain BWK49_RS24610 5650d6582f69df59b50f0a99287a90be 142 Pfam PF01575 MaoC like domain 15 125 3.4E-29 T 06-07-2017 IPR002539 MaoC-like domain BWK49_RS26000 64ab5abd1b888a3e02f44ced3034b5c6 215 SUPERFAMILY SSF54637 15 208 2.87E-44 T 06-07-2017 IPR029069 HotDog domain BWK49_RS26000 64ab5abd1b888a3e02f44ced3034b5c6 215 Gene3D G3DSA:3.10.129.10 79 212 3.5E-30 T 06-07-2017 IPR029069 HotDog domain BWK49_RS26000 64ab5abd1b888a3e02f44ced3034b5c6 215 Pfam PF03061 Thioesterase superfamily 127 200 7.2E-9 T 06-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 BWK49_RS26680 7a49f0d50972dd4b19c75f5ab0877e03 162 SUPERFAMILY SSF50475 12 161 4.46E-37 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 BWK49_RS26680 7a49f0d50972dd4b19c75f5ab0877e03 162 SMART SM00903 16 159 4.2E-39 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 BWK49_RS26680 7a49f0d50972dd4b19c75f5ab0877e03 162 Gene3D G3DSA:2.30.110.10 5 158 1.1E-43 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 BWK49_RS26680 7a49f0d50972dd4b19c75f5ab0877e03 162 Pfam PF01613 Flavin reductase like domain 17 160 3.6E-27 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 BWK49_RS20365 b62099b79a3d1b29dd933afc257a3fa8 112 SUPERFAMILY SSF54913 1 112 2.83E-44 T 06-07-2017 IPR011322 Nitrogen regulatory PII-like, alpha/beta BWK49_RS20365 b62099b79a3d1b29dd933afc257a3fa8 112 Gene3D G3DSA:3.30.70.120 1 112 6.5E-48 T 06-07-2017 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal BWK49_RS20365 b62099b79a3d1b29dd933afc257a3fa8 112 PIRSF PIRSF039144 1 112 3.9E-54 T 06-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 BWK49_RS20365 b62099b79a3d1b29dd933afc257a3fa8 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 06-07-2017 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 BWK49_RS20365 b62099b79a3d1b29dd933afc257a3fa8 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 06-07-2017 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 BWK49_RS20365 b62099b79a3d1b29dd933afc257a3fa8 112 PRINTS PR00340 P-II protein signature 2 17 7.4E-41 T 06-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 BWK49_RS20365 b62099b79a3d1b29dd933afc257a3fa8 112 PRINTS PR00340 P-II protein signature 52 75 7.4E-41 T 06-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 BWK49_RS20365 b62099b79a3d1b29dd933afc257a3fa8 112 PRINTS PR00340 P-II protein signature 23 41 7.4E-41 T 06-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 BWK49_RS20365 b62099b79a3d1b29dd933afc257a3fa8 112 PRINTS PR00340 P-II protein signature 83 103 7.4E-41 T 06-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 BWK49_RS20365 b62099b79a3d1b29dd933afc257a3fa8 112 SMART SM00938 4 105 1.6E-60 T 06-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 BWK49_RS20365 b62099b79a3d1b29dd933afc257a3fa8 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 2.4E-41 T 06-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 BWK49_RS21035 c40aa844c0da5cfb5a3f5bc2ddc00303 693 SUPERFAMILY SSF56091 12 326 5.94E-110 T 06-07-2017 BWK49_RS21035 c40aa844c0da5cfb5a3f5bc2ddc00303 693 Gene3D G3DSA:1.10.150.20 446 502 8.6E-15 T 06-07-2017 BWK49_RS21035 c40aa844c0da5cfb5a3f5bc2ddc00303 693 Gene3D G3DSA:3.30.470.30 127 262 4.7E-48 T 06-07-2017 BWK49_RS21035 c40aa844c0da5cfb5a3f5bc2ddc00303 693 Gene3D G3DSA:1.10.287.610 8 74 2.0E-25 T 06-07-2017 BWK49_RS21035 c40aa844c0da5cfb5a3f5bc2ddc00303 693 SMART SM00292 609 686 3.0E-14 T 06-07-2017 IPR001357 BRCT domain BWK49_RS21035 c40aa844c0da5cfb5a3f5bc2ddc00303 693 Hamap MF_01588 DNA ligase [ligA]. 11 683 50.787 T 06-07-2017 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 BWK49_RS21035 c40aa844c0da5cfb5a3f5bc2ddc00303 693 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 331 408 6.1E-30 T 06-07-2017 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 BWK49_RS21035 c40aa844c0da5cfb5a3f5bc2ddc00303 693 Gene3D G3DSA:3.40.50.10190 610 686 2.5E-24 T 06-07-2017 IPR001357 BRCT domain BWK49_RS21035 c40aa844c0da5cfb5a3f5bc2ddc00303 693 Gene3D G3DSA:1.10.150.20 521 601 7.7E-28 T 06-07-2017 BWK49_RS21035 c40aa844c0da5cfb5a3f5bc2ddc00303 693 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 123 152 - T 06-07-2017 IPR018239 NAD-dependent DNA ligase, active site BWK49_RS21035 c40aa844c0da5cfb5a3f5bc2ddc00303 693 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 611 682 4.7E-12 T 06-07-2017 IPR001357 BRCT domain BWK49_RS21035 c40aa844c0da5cfb5a3f5bc2ddc00303 693 SUPERFAMILY SSF50249 328 410 1.46E-25 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS21035 c40aa844c0da5cfb5a3f5bc2ddc00303 693 PIRSF PIRSF001604 5 687 2.4E-232 T 06-07-2017 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 BWK49_RS21035 c40aa844c0da5cfb5a3f5bc2ddc00303 693 Pfam PF12826 Helix-hairpin-helix motif 527 590 1.5E-21 T 06-07-2017 BWK49_RS21035 c40aa844c0da5cfb5a3f5bc2ddc00303 693 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 12 328 1.7E-121 T 06-07-2017 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 BWK49_RS21035 c40aa844c0da5cfb5a3f5bc2ddc00303 693 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 341 356 - T 06-07-2017 IPR033136 NAD-dependent DNA ligase, conserved site BWK49_RS21035 c40aa844c0da5cfb5a3f5bc2ddc00303 693 SMART SM00532 12 459 1.4E-254 T 06-07-2017 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 BWK49_RS21035 c40aa844c0da5cfb5a3f5bc2ddc00303 693 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 417 445 7.5E-8 T 06-07-2017 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 BWK49_RS21035 c40aa844c0da5cfb5a3f5bc2ddc00303 693 SUPERFAMILY SSF47781 413 600 5.93E-51 T 06-07-2017 IPR010994 RuvA domain 2-like BWK49_RS21035 c40aa844c0da5cfb5a3f5bc2ddc00303 693 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 20 678 2.5E-240 T 06-07-2017 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 BWK49_RS21035 c40aa844c0da5cfb5a3f5bc2ddc00303 693 Gene3D G3DSA:2.40.50.140 329 400 6.3E-29 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS21035 c40aa844c0da5cfb5a3f5bc2ddc00303 693 SUPERFAMILY SSF52113 611 684 4.09E-18 T 06-07-2017 IPR001357 BRCT domain BWK49_RS07710 62e8bcab298f625301f14718e2ad9a78 405 Pfam PF02803 Thiolase, C-terminal domain 281 403 1.5E-48 T 06-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 BWK49_RS07710 62e8bcab298f625301f14718e2ad9a78 405 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 402 1.4E-139 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 BWK49_RS07710 62e8bcab298f625301f14718e2ad9a78 405 SUPERFAMILY SSF53901 3 281 4.06E-66 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS07710 62e8bcab298f625301f14718e2ad9a78 405 PIRSF PIRSF000429 1 405 6.7E-133 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 BWK49_RS07710 62e8bcab298f625301f14718e2ad9a78 405 Gene3D G3DSA:3.40.47.10 288 403 3.5E-60 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS07710 62e8bcab298f625301f14718e2ad9a78 405 Gene3D G3DSA:3.40.47.10 170 208 3.5E-60 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS07710 62e8bcab298f625301f14718e2ad9a78 405 Pfam PF00108 Thiolase, N-terminal domain 5 272 3.2E-61 T 06-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 BWK49_RS07710 62e8bcab298f625301f14718e2ad9a78 405 ProSitePatterns PS00737 Thiolases signature 2. 350 366 - T 06-07-2017 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 BWK49_RS07710 62e8bcab298f625301f14718e2ad9a78 405 Gene3D G3DSA:3.40.47.10 4 125 1.9E-60 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS07710 62e8bcab298f625301f14718e2ad9a78 405 Gene3D G3DSA:3.40.47.10 209 287 1.9E-60 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS07710 62e8bcab298f625301f14718e2ad9a78 405 SUPERFAMILY SSF53901 282 403 2.07E-43 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS09705 f53aa9f1a04929ace1cad1acff31146f 268 Gene3D G3DSA:3.40.50.720 11 234 1.5E-52 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS09705 f53aa9f1a04929ace1cad1acff31146f 268 PIRSF PIRSF000126 3 266 5.9E-69 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS09705 f53aa9f1a04929ace1cad1acff31146f 268 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS09705 f53aa9f1a04929ace1cad1acff31146f 268 Pfam PF00106 short chain dehydrogenase 12 198 1.4E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS09705 f53aa9f1a04929ace1cad1acff31146f 268 SUPERFAMILY SSF51735 11 257 2.21E-54 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS09705 f53aa9f1a04929ace1cad1acff31146f 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 2.6E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS09705 f53aa9f1a04929ace1cad1acff31146f 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 2.6E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS09705 f53aa9f1a04929ace1cad1acff31146f 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 2.6E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS09705 f53aa9f1a04929ace1cad1acff31146f 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 2.6E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS09705 f53aa9f1a04929ace1cad1acff31146f 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 2.6E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS25220 a5247f9dcbb710fa2a7d9d0221a274b8 707 Pfam PF01757 Acyltransferase family 12 349 2.9E-25 T 06-07-2017 IPR002656 Acyltransferase 3 GO:0016747 BWK49_RS10865 ac78bda4abe555c27430198ff95559d2 336 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 88 9.5E-15 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 BWK49_RS10865 ac78bda4abe555c27430198ff95559d2 336 SUPERFAMILY SSF51735 128 299 2.41E-35 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS10865 ac78bda4abe555c27430198ff95559d2 336 Pfam PF00107 Zinc-binding dehydrogenase 161 291 6.2E-22 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 BWK49_RS10865 ac78bda4abe555c27430198ff95559d2 336 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 06-07-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 BWK49_RS10865 ac78bda4abe555c27430198ff95559d2 336 SUPERFAMILY SSF50129 1 160 3.46E-31 T 06-07-2017 IPR011032 GroES-like BWK49_RS10865 ac78bda4abe555c27430198ff95559d2 336 SMART SM00829 13 333 0.0096 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 BWK49_RS10865 ac78bda4abe555c27430198ff95559d2 336 Gene3D G3DSA:3.40.50.720 153 281 2.5E-35 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS10865 ac78bda4abe555c27430198ff95559d2 336 Gene3D G3DSA:3.90.180.10 1 152 6.9E-29 T 06-07-2017 IPR011032 GroES-like BWK49_RS16815 b141d7faa06f781931e1a0ac48276d1d 494 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 254 261 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 BWK49_RS16815 b141d7faa06f781931e1a0ac48276d1d 494 SUPERFAMILY SSF53720 10 486 2.49E-176 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 BWK49_RS16815 b141d7faa06f781931e1a0ac48276d1d 494 Pfam PF00171 Aldehyde dehydrogenase family 20 482 7.0E-181 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 BWK49_RS16815 b141d7faa06f781931e1a0ac48276d1d 494 Gene3D G3DSA:3.40.309.10 268 457 2.7E-74 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 BWK49_RS16815 b141d7faa06f781931e1a0ac48276d1d 494 Gene3D G3DSA:3.40.605.10 12 267 4.3E-101 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 BWK49_RS03070 b56a9973ee54c8d3c15c4b48bcbdc848 172 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 85 96 - T 06-07-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 BWK49_RS03070 b56a9973ee54c8d3c15c4b48bcbdc848 172 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 5 133 6.1E-30 T 06-07-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 BWK49_RS03070 b56a9973ee54c8d3c15c4b48bcbdc848 172 SUPERFAMILY SSF55083 1 154 8.11E-39 T 06-07-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 BWK49_RS03070 b56a9973ee54c8d3c15c4b48bcbdc848 172 Gene3D G3DSA:3.30.70.560 3 156 4.7E-42 T 06-07-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 BWK49_RS03070 b56a9973ee54c8d3c15c4b48bcbdc848 172 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 4 133 3.1E-39 T 06-07-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 BWK49_RS27735 ce51b1e3df2256572904d36e655a67ad 251 Pfam PF03734 L,D-transpeptidase catalytic domain 130 249 1.7E-19 T 06-07-2017 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 BWK49_RS27735 ce51b1e3df2256572904d36e655a67ad 251 Pfam PF13205 Bacterial Ig-like domain 35 114 1.4E-6 T 06-07-2017 IPR032812 SbsA, Ig-like domain BWK49_RS27735 ce51b1e3df2256572904d36e655a67ad 251 Gene3D G3DSA:2.40.440.10 129 250 5.2E-23 T 06-07-2017 BWK49_RS27735 ce51b1e3df2256572904d36e655a67ad 251 SUPERFAMILY SSF141523 128 249 8.76E-32 T 06-07-2017 BWK49_RS28485 0f88fa5361b6b1da4a5d0ad4acae40cd 195 SUPERFAMILY SSF46689 144 184 9.86E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS28485 0f88fa5361b6b1da4a5d0ad4acae40cd 195 Pfam PF02796 Helix-turn-helix domain of resolvase 145 185 2.4E-8 T 06-07-2017 IPR006120 Resolvase, HTH domain GO:0000150|GO:0003677|GO:0006310 BWK49_RS28485 0f88fa5361b6b1da4a5d0ad4acae40cd 195 SUPERFAMILY SSF53041 4 137 2.88E-34 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 BWK49_RS28485 0f88fa5361b6b1da4a5d0ad4acae40cd 195 ProSitePatterns PS00397 Site-specific recombinases active site. 7 15 - T 06-07-2017 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 BWK49_RS28485 0f88fa5361b6b1da4a5d0ad4acae40cd 195 ProSitePatterns PS00398 Site-specific recombinases signature 2. 60 72 - T 06-07-2017 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 BWK49_RS28485 0f88fa5361b6b1da4a5d0ad4acae40cd 195 Gene3D G3DSA:1.10.10.60 144 184 9.3E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS28485 0f88fa5361b6b1da4a5d0ad4acae40cd 195 SMART SM00857 4 141 6.6E-40 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 BWK49_RS28485 0f88fa5361b6b1da4a5d0ad4acae40cd 195 Pfam PF00239 Resolvase, N terminal domain 5 138 3.6E-32 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 BWK49_RS28485 0f88fa5361b6b1da4a5d0ad4acae40cd 195 Gene3D G3DSA:3.40.50.1390 4 123 2.8E-35 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 BWK49_RS15315 dffeec1ce722b14711298788720a151c 293 Gene3D G3DSA:3.20.20.30 1 267 6.8E-68 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS15315 dffeec1ce722b14711298788720a151c 293 TIGRFAM TIGR03619 F420_Rv2161c: probable F420-dependent oxidoreductase, Rv2161c family 22 268 5.3E-83 T 06-07-2017 IPR019921 Luciferase-like, F420-dependent oxidoreductase, Rv2161c, predicted BWK49_RS15315 dffeec1ce722b14711298788720a151c 293 SUPERFAMILY SSF51679 12 286 2.36E-62 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS15315 dffeec1ce722b14711298788720a151c 293 Pfam PF00296 Luciferase-like monooxygenase 2 247 5.0E-50 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS26495 d14ce8aeba5fecaa8d7ac139d34860ed 87 Gene3D G3DSA:4.10.640.10 9 84 5.1E-26 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS26495 d14ce8aeba5fecaa8d7ac139d34860ed 87 TIGRFAM TIGR00165 S18: ribosomal protein bS18 27 80 2.2E-21 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS26495 d14ce8aeba5fecaa8d7ac139d34860ed 87 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 31 80 9.0E-22 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS26495 d14ce8aeba5fecaa8d7ac139d34860ed 87 Pfam PF01084 Ribosomal protein S18 30 78 2.6E-22 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS26495 d14ce8aeba5fecaa8d7ac139d34860ed 87 PRINTS PR00974 Ribosomal protein S18 family signature 56 70 2.3E-16 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS26495 d14ce8aeba5fecaa8d7ac139d34860ed 87 PRINTS PR00974 Ribosomal protein S18 family signature 70 80 2.3E-16 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS26495 d14ce8aeba5fecaa8d7ac139d34860ed 87 PRINTS PR00974 Ribosomal protein S18 family signature 48 55 2.3E-16 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS26495 d14ce8aeba5fecaa8d7ac139d34860ed 87 PRINTS PR00974 Ribosomal protein S18 family signature 38 48 2.3E-16 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS26495 d14ce8aeba5fecaa8d7ac139d34860ed 87 SUPERFAMILY SSF46911 17 84 1.96E-23 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS26495 d14ce8aeba5fecaa8d7ac139d34860ed 87 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 3 83 18.49 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS08975 1e0ee5545f588d74ca5064e11af8e1aa 121 Gene3D G3DSA:2.60.15.10 3 91 6.3E-23 T 06-07-2017 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 BWK49_RS08975 1e0ee5545f588d74ca5064e11af8e1aa 121 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 4 84 1.8E-23 T 06-07-2017 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 BWK49_RS08975 1e0ee5545f588d74ca5064e11af8e1aa 121 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 4 103 1.2E-24 T 06-07-2017 IPR001469 ATPase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 BWK49_RS08975 1e0ee5545f588d74ca5064e11af8e1aa 121 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 17 84 3.0E-30 T 06-07-2017 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 BWK49_RS08975 1e0ee5545f588d74ca5064e11af8e1aa 121 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 2 116 17.042 T 06-07-2017 IPR001469 ATPase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 BWK49_RS08975 1e0ee5545f588d74ca5064e11af8e1aa 121 SUPERFAMILY SSF51344 4 85 1.12E-18 T 06-07-2017 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 BWK49_RS12800 4923146eeda71e2cd09d5d46d1c6a24b 149 Gene3D G3DSA:3.30.530.20 2 144 4.2E-10 T 06-07-2017 IPR023393 START-like domain BWK49_RS12800 4923146eeda71e2cd09d5d46d1c6a24b 149 SUPERFAMILY SSF55961 2 146 5.3E-22 T 06-07-2017 BWK49_RS12800 4923146eeda71e2cd09d5d46d1c6a24b 149 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 2 141 5.7E-7 T 06-07-2017 IPR019587 Polyketide cyclase/dehydrase BWK49_RS02525 589cb91d1ed664e18b591f6d592dfe47 421 Gene3D G3DSA:3.40.1160.10 3 244 7.5E-73 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase BWK49_RS02525 589cb91d1ed664e18b591f6d592dfe47 421 Pfam PF00696 Amino acid kinase family 3 231 1.9E-53 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase BWK49_RS02525 589cb91d1ed664e18b591f6d592dfe47 421 Pfam PF13840 ACT domain 341 403 3.6E-12 T 06-07-2017 IPR027795 GATS-like ACT domain BWK49_RS02525 589cb91d1ed664e18b591f6d592dfe47 421 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 06-07-2017 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 BWK49_RS02525 589cb91d1ed664e18b591f6d592dfe47 421 Gene3D G3DSA:3.30.70.260 266 334 5.7E-4 T 06-07-2017 BWK49_RS02525 589cb91d1ed664e18b591f6d592dfe47 421 Pfam PF01842 ACT domain 269 329 1.2E-10 T 06-07-2017 IPR002912 ACT domain GO:0008152|GO:0016597 BWK49_RS02525 589cb91d1ed664e18b591f6d592dfe47 421 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 2 406 3.0E-139 T 06-07-2017 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 BWK49_RS02525 589cb91d1ed664e18b591f6d592dfe47 421 PIRSF PIRSF000726 57 414 4.1E-128 T 06-07-2017 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 BWK49_RS02525 589cb91d1ed664e18b591f6d592dfe47 421 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 2 405 1.3E-122 T 06-07-2017 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 BWK49_RS02525 589cb91d1ed664e18b591f6d592dfe47 421 SUPERFAMILY SSF55021 250 329 4.34E-19 T 06-07-2017 BWK49_RS02525 589cb91d1ed664e18b591f6d592dfe47 421 SUPERFAMILY SSF55021 332 409 1.05E-20 T 06-07-2017 BWK49_RS02525 589cb91d1ed664e18b591f6d592dfe47 421 SUPERFAMILY SSF53633 4 243 9.82E-73 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase BWK49_RS16860 801c089938be05b6dc8afe121d3c2e8e 213 Pfam PF04542 Sigma-70 region 2 28 94 1.1E-16 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS16860 801c089938be05b6dc8afe121d3c2e8e 213 Gene3D G3DSA:1.10.1740.10 8 100 2.3E-27 T 06-07-2017 BWK49_RS16860 801c089938be05b6dc8afe121d3c2e8e 213 SUPERFAMILY SSF88659 138 206 4.49E-11 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS16860 801c089938be05b6dc8afe121d3c2e8e 213 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 24 204 5.4E-27 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS16860 801c089938be05b6dc8afe121d3c2e8e 213 Gene3D G3DSA:1.10.10.10 144 208 9.8E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS16860 801c089938be05b6dc8afe121d3c2e8e 213 Pfam PF08281 Sigma-70, region 4 155 199 7.6E-10 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS16860 801c089938be05b6dc8afe121d3c2e8e 213 SUPERFAMILY SSF88946 8 98 3.27E-25 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS15035 54dfc9c6e6ce06215415c2d6fc7ef0ef 456 SMART SM01091 354 444 1.8E-22 T 06-07-2017 IPR005170 Transporter-associated domain BWK49_RS15035 54dfc9c6e6ce06215415c2d6fc7ef0ef 456 Pfam PF03471 Transporter associated domain 358 442 7.8E-19 T 06-07-2017 IPR005170 Transporter-associated domain BWK49_RS15035 54dfc9c6e6ce06215415c2d6fc7ef0ef 456 Gene3D G3DSA:3.30.465.10 335 442 5.5E-23 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 BWK49_RS15035 54dfc9c6e6ce06215415c2d6fc7ef0ef 456 Pfam PF01595 Domain of unknown function DUF21 12 202 3.6E-35 T 06-07-2017 IPR002550 Domain of unknown function DUF21 BWK49_RS15035 54dfc9c6e6ce06215415c2d6fc7ef0ef 456 SUPERFAMILY SSF54631 215 355 4.93E-27 T 06-07-2017 BWK49_RS15035 54dfc9c6e6ce06215415c2d6fc7ef0ef 456 SMART SM00116 292 340 4.9 T 06-07-2017 IPR000644 CBS domain BWK49_RS15035 54dfc9c6e6ce06215415c2d6fc7ef0ef 456 SMART SM00116 229 278 0.04 T 06-07-2017 IPR000644 CBS domain BWK49_RS15035 54dfc9c6e6ce06215415c2d6fc7ef0ef 456 Gene3D G3DSA:3.10.580.10 208 334 1.9E-19 T 06-07-2017 BWK49_RS15035 54dfc9c6e6ce06215415c2d6fc7ef0ef 456 Pfam PF00571 CBS domain 221 273 2.5E-4 T 06-07-2017 IPR000644 CBS domain BWK49_RS15035 54dfc9c6e6ce06215415c2d6fc7ef0ef 456 Pfam PF00571 CBS domain 292 340 6.6E-4 T 06-07-2017 IPR000644 CBS domain BWK49_RS15035 54dfc9c6e6ce06215415c2d6fc7ef0ef 456 SUPERFAMILY SSF56176 358 445 3.54E-17 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 BWK49_RS13275 d7f271b3ff173a00ef840e5a7bfb657b 1264 Pfam PF02607 B12 binding domain 680 757 5.0E-24 T 06-07-2017 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 BWK49_RS13275 d7f271b3ff173a00ef840e5a7bfb657b 1264 SUPERFAMILY SSF52242 775 925 9.55E-45 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 BWK49_RS13275 d7f271b3ff173a00ef840e5a7bfb657b 1264 SUPERFAMILY SSF47644 674 764 6.54E-26 T 06-07-2017 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 BWK49_RS13275 d7f271b3ff173a00ef840e5a7bfb657b 1264 Gene3D G3DSA:3.20.20.330 30 386 6.6E-122 T 06-07-2017 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 BWK49_RS13275 d7f271b3ff173a00ef840e5a7bfb657b 1264 SUPERFAMILY SSF51717 379 653 1.96E-89 T 06-07-2017 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 BWK49_RS13275 d7f271b3ff173a00ef840e5a7bfb657b 1264 Gene3D G3DSA:3.10.196.10 989 1263 1.8E-110 T 06-07-2017 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0005622|GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 BWK49_RS13275 d7f271b3ff173a00ef840e5a7bfb657b 1264 Pfam PF02965 Vitamin B12 dependent methionine synthase, activation domain 969 1244 1.3E-121 T 06-07-2017 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0005622|GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 BWK49_RS13275 d7f271b3ff173a00ef840e5a7bfb657b 1264 Pfam PF02310 B12 binding domain 779 869 3.9E-20 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 BWK49_RS13275 d7f271b3ff173a00ef840e5a7bfb657b 1264 TIGRFAM TIGR02082 metH: methionine synthase 37 1228 0.0 T 06-07-2017 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0008898|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 BWK49_RS13275 d7f271b3ff173a00ef840e5a7bfb657b 1264 Pfam PF02574 Homocysteine S-methyltransferase 42 348 6.8E-87 T 06-07-2017 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 BWK49_RS13275 d7f271b3ff173a00ef840e5a7bfb657b 1264 Gene3D G3DSA:1.10.1240.10 673 762 1.3E-35 T 06-07-2017 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 BWK49_RS13275 d7f271b3ff173a00ef840e5a7bfb657b 1264 SUPERFAMILY SSF82282 32 422 2.88E-114 T 06-07-2017 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 BWK49_RS13275 d7f271b3ff173a00ef840e5a7bfb657b 1264 SMART SM01018 678 765 4.2E-42 T 06-07-2017 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 BWK49_RS13275 d7f271b3ff173a00ef840e5a7bfb657b 1264 PIRSF PIRSF000381 26 1231 0.0 T 06-07-2017 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0008898|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 BWK49_RS13275 d7f271b3ff173a00ef840e5a7bfb657b 1264 Gene3D G3DSA:3.20.20.20 387 659 7.1E-114 T 06-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 BWK49_RS13275 d7f271b3ff173a00ef840e5a7bfb657b 1264 Gene3D G3DSA:3.40.50.280 776 926 2.0E-64 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 BWK49_RS13275 d7f271b3ff173a00ef840e5a7bfb657b 1264 SUPERFAMILY SSF56507 932 1263 4.97E-127 T 06-07-2017 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0005622|GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 BWK49_RS13275 d7f271b3ff173a00ef840e5a7bfb657b 1264 Pfam PF00809 Pterin binding enzyme 383 621 7.9E-59 T 06-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 BWK49_RS25620 17d15737fed43f2dda94e9b7f13167bf 541 SUPERFAMILY SSF52029 184 374 4.78E-81 T 06-07-2017 IPR027409 GroEL-like apical domain BWK49_RS25620 17d15737fed43f2dda94e9b7f13167bf 541 Gene3D G3DSA:1.10.560.10 367 515 9.6E-40 T 06-07-2017 IPR027413 GroEL-like equatorial domain BWK49_RS25620 17d15737fed43f2dda94e9b7f13167bf 541 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 524 3.0E-251 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 BWK49_RS25620 17d15737fed43f2dda94e9b7f13167bf 541 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 522 1.5E-96 T 06-07-2017 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 BWK49_RS25620 17d15737fed43f2dda94e9b7f13167bf 541 Gene3D G3DSA:3.50.7.10 187 366 1.6E-96 T 06-07-2017 IPR027409 GroEL-like apical domain BWK49_RS25620 17d15737fed43f2dda94e9b7f13167bf 541 Gene3D G3DSA:1.10.560.10 3 186 2.1E-48 T 06-07-2017 IPR027413 GroEL-like equatorial domain BWK49_RS25620 17d15737fed43f2dda94e9b7f13167bf 541 SUPERFAMILY SSF48592 1 226 1.96E-63 T 06-07-2017 BWK49_RS25620 17d15737fed43f2dda94e9b7f13167bf 541 ProSitePatterns PS00296 Chaperonins cpn60 signature. 403 414 - T 06-07-2017 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020 BWK49_RS25620 17d15737fed43f2dda94e9b7f13167bf 541 SUPERFAMILY SSF48592 309 518 1.68E-29 T 06-07-2017 BWK49_RS25620 17d15737fed43f2dda94e9b7f13167bf 541 Hamap MF_00600 60 kDa chaperonin [groL]. 1 539 41.166 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 BWK49_RS25620 17d15737fed43f2dda94e9b7f13167bf 541 PRINTS PR00298 60kDa chaperonin signature 26 52 4.3E-71 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 BWK49_RS25620 17d15737fed43f2dda94e9b7f13167bf 541 PRINTS PR00298 60kDa chaperonin signature 348 373 4.3E-71 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 BWK49_RS25620 17d15737fed43f2dda94e9b7f13167bf 541 PRINTS PR00298 60kDa chaperonin signature 266 289 4.3E-71 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 BWK49_RS25620 17d15737fed43f2dda94e9b7f13167bf 541 PRINTS PR00298 60kDa chaperonin signature 82 109 4.3E-71 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 BWK49_RS25620 17d15737fed43f2dda94e9b7f13167bf 541 PRINTS PR00298 60kDa chaperonin signature 396 417 4.3E-71 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 BWK49_RS18460 60b44ceda276359537b019403b0eb446 140 SUPERFAMILY SSF50331 10 128 1.53E-16 T 06-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal BWK49_RS18460 60b44ceda276359537b019403b0eb446 140 Gene3D G3DSA:2.40.50.100 66 128 2.7E-20 T 06-07-2017 BWK49_RS18460 60b44ceda276359537b019403b0eb446 140 Pfam PF12728 Helix-turn-helix domain 4 52 1.5E-9 T 06-07-2017 BWK49_RS18460 60b44ceda276359537b019403b0eb446 140 Pfam PF03459 TOBE domain 66 128 3.4E-10 T 06-07-2017 IPR005116 Transport-associated OB, type 1 BWK49_RS18460 60b44ceda276359537b019403b0eb446 140 Gene3D G3DSA:1.10.10.10 4 40 2.7E-6 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS18460 60b44ceda276359537b019403b0eb446 140 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 4 33 6.2E-8 T 06-07-2017 IPR010093 SinI-like, DNA-binding domain GO:0003677 BWK49_RS12475 ae865518130b27860fc39c827ed8ff24 929 PIRSF PIRSF000156 25 923 0.0 T 06-07-2017 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 BWK49_RS12475 ae865518130b27860fc39c827ed8ff24 929 SUPERFAMILY SSF52922 737 920 2.47E-51 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 BWK49_RS12475 ae865518130b27860fc39c827ed8ff24 929 SUPERFAMILY SSF52518 85 500 4.59E-130 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS12475 ae865518130b27860fc39c827ed8ff24 929 Gene3D G3DSA:3.40.50.920 742 920 5.3E-69 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 BWK49_RS12475 ae865518130b27860fc39c827ed8ff24 929 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 33 922 0.0 T 06-07-2017 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 BWK49_RS12475 ae865518130b27860fc39c827ed8ff24 929 Gene3D G3DSA:3.40.50.970 85 501 4.4E-152 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS12475 ae865518130b27860fc39c827ed8ff24 929 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 165 331 1.1E-9 T 06-07-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 BWK49_RS12475 ae865518130b27860fc39c827ed8ff24 929 SUPERFAMILY SSF52518 506 733 1.65E-87 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS12475 ae865518130b27860fc39c827ed8ff24 929 Gene3D G3DSA:3.40.50.970 505 738 2.1E-110 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS10475 0ed31ef853430364ff0d5a258af7231d 388 SUPERFAMILY SSF53686 46 352 1.96E-68 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme BWK49_RS10475 0ed31ef853430364ff0d5a258af7231d 388 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 70 88 - T 06-07-2017 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 BWK49_RS10475 0ed31ef853430364ff0d5a258af7231d 388 Gene3D G3DSA:3.40.50.1100 191 349 4.6E-38 T 06-07-2017 BWK49_RS10475 0ed31ef853430364ff0d5a258af7231d 388 Gene3D G3DSA:3.40.50.1100 45 79 4.6E-38 T 06-07-2017 BWK49_RS10475 0ed31ef853430364ff0d5a258af7231d 388 Gene3D G3DSA:3.40.50.1100 80 165 4.3E-24 T 06-07-2017 BWK49_RS10475 0ed31ef853430364ff0d5a258af7231d 388 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 48 329 4.5E-48 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme BWK49_RS10605 0ed31ef853430364ff0d5a258af7231d 388 SUPERFAMILY SSF53686 46 352 1.96E-68 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme BWK49_RS10605 0ed31ef853430364ff0d5a258af7231d 388 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 70 88 - T 06-07-2017 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 BWK49_RS10605 0ed31ef853430364ff0d5a258af7231d 388 Gene3D G3DSA:3.40.50.1100 191 349 4.6E-38 T 06-07-2017 BWK49_RS10605 0ed31ef853430364ff0d5a258af7231d 388 Gene3D G3DSA:3.40.50.1100 45 79 4.6E-38 T 06-07-2017 BWK49_RS10605 0ed31ef853430364ff0d5a258af7231d 388 Gene3D G3DSA:3.40.50.1100 80 165 4.3E-24 T 06-07-2017 BWK49_RS10605 0ed31ef853430364ff0d5a258af7231d 388 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 48 329 4.5E-48 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme BWK49_RS15800 ba17e5e376539941a3e40ae8ab515954 645 SUPERFAMILY SSF51905 146 381 4.17E-52 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS15800 ba17e5e376539941a3e40ae8ab515954 645 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 150 358 2.5E-17 T 06-07-2017 BWK49_RS15800 ba17e5e376539941a3e40ae8ab515954 645 Gene3D G3DSA:3.50.50.60 455 642 1.3E-11 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS15800 ba17e5e376539941a3e40ae8ab515954 645 Gene3D G3DSA:3.50.50.60 139 353 1.0E-60 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS15800 ba17e5e376539941a3e40ae8ab515954 645 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 317 342 2.2E-6 T 06-07-2017 BWK49_RS15800 ba17e5e376539941a3e40ae8ab515954 645 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 148 170 2.2E-6 T 06-07-2017 BWK49_RS15800 ba17e5e376539941a3e40ae8ab515954 645 SUPERFAMILY SSF51905 454 621 3.63E-14 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS15800 ba17e5e376539941a3e40ae8ab515954 645 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 149 168 4.7E-6 T 06-07-2017 BWK49_RS15800 ba17e5e376539941a3e40ae8ab515954 645 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 317 335 4.7E-6 T 06-07-2017 BWK49_RS11000 bb1b98a39443e187aae3d4344fdf2ceb 319 Gene3D G3DSA:1.20.140.10 174 315 1.5E-29 T 06-07-2017 BWK49_RS11000 bb1b98a39443e187aae3d4344fdf2ceb 319 SUPERFAMILY SSF56645 6 112 7.59E-14 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS11000 bb1b98a39443e187aae3d4344fdf2ceb 319 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 174 315 3.1E-20 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS11000 bb1b98a39443e187aae3d4344fdf2ceb 319 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 22 99 1.4E-9 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS11000 bb1b98a39443e187aae3d4344fdf2ceb 319 Gene3D G3DSA:1.10.540.10 24 100 4.0E-10 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS11000 bb1b98a39443e187aae3d4344fdf2ceb 319 SUPERFAMILY SSF47203 174 315 5.64E-32 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS26700 f9bd4582362686f18f401e41040fa493 122 Gene3D G3DSA:3.10.180.10 4 119 3.8E-19 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS26700 f9bd4582362686f18f401e41040fa493 122 SUPERFAMILY SSF54593 2 119 4.83E-21 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS26700 f9bd4582362686f18f401e41040fa493 122 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 116 1.4E-6 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain BWK49_RS16210 4b7172654c7620e5fedb92fbb725ac1c 367 SMART SM00421 305 362 1.2E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS16210 4b7172654c7620e5fedb92fbb725ac1c 367 Gene3D G3DSA:1.10.10.10 304 364 2.6E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS16210 4b7172654c7620e5fedb92fbb725ac1c 367 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 308 322 3.0E-7 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS16210 4b7172654c7620e5fedb92fbb725ac1c 367 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 338 350 3.0E-7 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS16210 4b7172654c7620e5fedb92fbb725ac1c 367 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 322 338 3.0E-7 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS16210 4b7172654c7620e5fedb92fbb725ac1c 367 Gene3D G3DSA:3.30.450.20 167 270 8.4E-4 T 06-07-2017 BWK49_RS16210 4b7172654c7620e5fedb92fbb725ac1c 367 SUPERFAMILY SSF46894 296 364 1.97E-16 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 BWK49_RS16210 4b7172654c7620e5fedb92fbb725ac1c 367 Pfam PF00196 Bacterial regulatory proteins, luxR family 307 361 2.6E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS28685 bddd00f2d270695141f59d0a56910d90 3422 Pfam PF00550 Phosphopantetheine attachment site 954 1013 3.3E-8 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS28685 bddd00f2d270695141f59d0a56910d90 3422 Pfam PF00550 Phosphopantetheine attachment site 2458 2517 1.4E-8 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS28685 bddd00f2d270695141f59d0a56910d90 3422 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 483 872 8.6E-123 T 06-07-2017 IPR010071 Amino acid adenylation domain BWK49_RS28685 bddd00f2d270695141f59d0a56910d90 3422 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1972 2375 2.5E-131 T 06-07-2017 IPR010071 Amino acid adenylation domain BWK49_RS28685 bddd00f2d270695141f59d0a56910d90 3422 SUPERFAMILY SSF56801 1908 2468 6.93E-148 T 06-07-2017 BWK49_RS28685 bddd00f2d270695141f59d0a56910d90 3422 Gene3D G3DSA:3.30.300.30 2346 2459 5.9E-38 T 06-07-2017 BWK49_RS28685 bddd00f2d270695141f59d0a56910d90 3422 Gene3D G3DSA:3.30.300.30 843 954 2.3E-37 T 06-07-2017 BWK49_RS28685 bddd00f2d270695141f59d0a56910d90 3422 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 1337 1494 8.7E-31 T 06-07-2017 IPR010060 Non-ribosomal peptide synthase BWK49_RS28685 bddd00f2d270695141f59d0a56910d90 3422 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 2844 3000 6.8E-33 T 06-07-2017 IPR010060 Non-ribosomal peptide synthase BWK49_RS28685 bddd00f2d270695141f59d0a56910d90 3422 SUPERFAMILY SSF52777 1681 1912 7.56E-51 T 06-07-2017 BWK49_RS28685 bddd00f2d270695141f59d0a56910d90 3422 Pfam PF00668 Condensation domain 1050 1322 1.9E-19 T 06-07-2017 IPR001242 Condensation domain BWK49_RS28685 bddd00f2d270695141f59d0a56910d90 3422 Pfam PF00668 Condensation domain 2555 2825 4.1E-25 T 06-07-2017 IPR001242 Condensation domain BWK49_RS28685 bddd00f2d270695141f59d0a56910d90 3422 Pfam PF00668 Condensation domain 1502 1787 1.5E-52 T 06-07-2017 IPR001242 Condensation domain BWK49_RS28685 bddd00f2d270695141f59d0a56910d90 3422 Pfam PF00668 Condensation domain 3007 3296 2.9E-57 T 06-07-2017 IPR001242 Condensation domain BWK49_RS28685 bddd00f2d270695141f59d0a56910d90 3422 Pfam PF00668 Condensation domain 7 299 5.0E-28 T 06-07-2017 IPR001242 Condensation domain BWK49_RS28685 bddd00f2d270695141f59d0a56910d90 3422 SUPERFAMILY SSF52777 9 182 4.34E-28 T 06-07-2017 BWK49_RS28685 bddd00f2d270695141f59d0a56910d90 3422 SUPERFAMILY SSF47336 943 1013 4.84E-15 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS28685 bddd00f2d270695141f59d0a56910d90 3422 SUPERFAMILY SSF52777 1211 1471 6.0E-24 T 06-07-2017 BWK49_RS28685 bddd00f2d270695141f59d0a56910d90 3422 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2479 2494 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site BWK49_RS28685 bddd00f2d270695141f59d0a56910d90 3422 SUPERFAMILY SSF52777 3183 3418 1.89E-52 T 06-07-2017 BWK49_RS28685 bddd00f2d270695141f59d0a56910d90 3422 Gene3D G3DSA:2.30.38.10 2263 2341 1.5E-20 T 06-07-2017 BWK49_RS28685 bddd00f2d270695141f59d0a56910d90 3422 Gene3D G3DSA:2.30.38.10 760 836 9.6E-21 T 06-07-2017 BWK49_RS28685 bddd00f2d270695141f59d0a56910d90 3422 Gene3D G3DSA:3.40.50.980 457 610 8.8E-47 T 06-07-2017 BWK49_RS28685 bddd00f2d270695141f59d0a56910d90 3422 Gene3D G3DSA:3.40.50.980 1946 2098 2.4E-47 T 06-07-2017 BWK49_RS28685 bddd00f2d270695141f59d0a56910d90 3422 SUPERFAMILY SSF52777 1028 1194 4.45E-22 T 06-07-2017 BWK49_RS28685 bddd00f2d270695141f59d0a56910d90 3422 Pfam PF00501 AMP-binding enzyme 462 848 2.2E-84 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS28685 bddd00f2d270695141f59d0a56910d90 3422 Pfam PF00501 AMP-binding enzyme 1952 2351 7.6E-91 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS28685 bddd00f2d270695141f59d0a56910d90 3422 SUPERFAMILY SSF47336 2447 2517 2.62E-15 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS28685 bddd00f2d270695141f59d0a56910d90 3422 ProSitePatterns PS00012 Phosphopantetheine attachment site. 975 990 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site BWK49_RS28685 bddd00f2d270695141f59d0a56910d90 3422 Gene3D G3DSA:1.10.1200.10 955 1016 3.6E-23 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS28685 bddd00f2d270695141f59d0a56910d90 3422 Gene3D G3DSA:1.10.1200.10 2460 2519 4.5E-22 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS28685 bddd00f2d270695141f59d0a56910d90 3422 SUPERFAMILY SSF52777 2536 2699 2.56E-25 T 06-07-2017 BWK49_RS28685 bddd00f2d270695141f59d0a56910d90 3422 SUPERFAMILY SSF52777 2711 2976 1.33E-25 T 06-07-2017 BWK49_RS28685 bddd00f2d270695141f59d0a56910d90 3422 SUPERFAMILY SSF52777 1497 1692 3.11E-43 T 06-07-2017 BWK49_RS28685 bddd00f2d270695141f59d0a56910d90 3422 SUPERFAMILY SSF52777 189 423 6.11E-28 T 06-07-2017 BWK49_RS28685 bddd00f2d270695141f59d0a56910d90 3422 SUPERFAMILY SSF52777 3006 3198 1.67E-40 T 06-07-2017 BWK49_RS28685 bddd00f2d270695141f59d0a56910d90 3422 Pfam PF13193 AMP-binding enzyme C-terminal domain 856 927 2.6E-9 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS28685 bddd00f2d270695141f59d0a56910d90 3422 Pfam PF13193 AMP-binding enzyme C-terminal domain 2359 2430 1.0E-10 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS28685 bddd00f2d270695141f59d0a56910d90 3422 ProSitePatterns PS00455 Putative AMP-binding domain signature. 601 612 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS28685 bddd00f2d270695141f59d0a56910d90 3422 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2090 2101 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS28685 bddd00f2d270695141f59d0a56910d90 3422 SUPERFAMILY SSF56801 417 964 9.42E-142 T 06-07-2017 BWK49_RS28685 bddd00f2d270695141f59d0a56910d90 3422 Gene3D G3DSA:3.40.50.980 2099 2262 1.3E-42 T 06-07-2017 BWK49_RS28685 bddd00f2d270695141f59d0a56910d90 3422 Gene3D G3DSA:3.40.50.980 611 759 2.9E-35 T 06-07-2017 BWK49_RS18885 287eb2cdbb678bffe8c7ad716709d3be 278 Pfam PF13622 Thioesterase-like superfamily 32 269 1.3E-53 T 06-07-2017 BWK49_RS18885 287eb2cdbb678bffe8c7ad716709d3be 278 Gene3D G3DSA:3.10.129.10 3 113 3.2E-41 T 06-07-2017 IPR029069 HotDog domain BWK49_RS18885 287eb2cdbb678bffe8c7ad716709d3be 278 SUPERFAMILY SSF54637 115 273 3.15E-45 T 06-07-2017 IPR029069 HotDog domain BWK49_RS18885 287eb2cdbb678bffe8c7ad716709d3be 278 SUPERFAMILY SSF54637 3 112 1.16E-31 T 06-07-2017 IPR029069 HotDog domain BWK49_RS18885 287eb2cdbb678bffe8c7ad716709d3be 278 Gene3D G3DSA:3.10.129.10 123 273 3.5E-46 T 06-07-2017 IPR029069 HotDog domain BWK49_RS18885 287eb2cdbb678bffe8c7ad716709d3be 278 TIGRFAM TIGR00189 tesB: acyl-CoA thioesterase II 7 271 7.1E-93 T 06-07-2017 IPR003703 Acyl-CoA thioesterase GO:0006637|GO:0047617 Reactome: R-HSA-193368|Reactome: R-HSA-2046106|Reactome: R-HSA-389887|Reactome: R-HSA-390247|Reactome: R-HSA-75105 BWK49_RS00795 88969560bc13dd43757711510ee4dce3 190 SUPERFAMILY SSF46785 2 180 4.09E-40 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS00795 88969560bc13dd43757711510ee4dce3 190 Gene3D G3DSA:1.10.10.10 2 85 1.9E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS00795 88969560bc13dd43757711510ee4dce3 190 Pfam PF03551 Transcriptional regulator PadR-like family 7 80 2.9E-14 T 06-07-2017 IPR005149 Transcription regulator PadR, N-terminal BWK49_RS00795 88969560bc13dd43757711510ee4dce3 190 Pfam PF10400 Virulence activator alpha C-term 92 179 3.9E-21 T 06-07-2017 IPR018309 Transcription regulator PadR, C-terminal BWK49_RS00920 c12f24d839eb152167c03e77f2f73011 1527 SUPERFAMILY SSF56235 18 443 1.0E-147 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal BWK49_RS00920 c12f24d839eb152167c03e77f2f73011 1527 Pfam PF01493 GXGXG motif 1271 1459 1.0E-80 T 06-07-2017 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 BWK49_RS00920 c12f24d839eb152167c03e77f2f73011 1527 Gene3D G3DSA:2.160.20.60 1245 1519 1.7E-107 T 06-07-2017 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 BWK49_RS00920 c12f24d839eb152167c03e77f2f73011 1527 Pfam PF00310 Glutamine amidotransferases class-II 18 439 3.3E-180 T 06-07-2017 IPR017932 Glutamine amidotransferase type 2 domain BWK49_RS00920 c12f24d839eb152167c03e77f2f73011 1527 SUPERFAMILY SSF51395 457 1225 8.14E-264 T 06-07-2017 BWK49_RS00920 c12f24d839eb152167c03e77f2f73011 1527 Gene3D G3DSA:3.20.20.70 814 1227 1.6E-177 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 BWK49_RS00920 c12f24d839eb152167c03e77f2f73011 1527 Gene3D G3DSA:3.60.20.10 18 450 1.1E-183 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal BWK49_RS00920 c12f24d839eb152167c03e77f2f73011 1527 SUPERFAMILY SSF69336 1240 1506 9.68E-93 T 06-07-2017 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 BWK49_RS00920 c12f24d839eb152167c03e77f2f73011 1527 Pfam PF01645 Conserved region in glutamate synthase 821 1190 2.2E-154 T 06-07-2017 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 BWK49_RS00920 c12f24d839eb152167c03e77f2f73011 1527 Pfam PF04898 Glutamate synthase central domain 465 757 4.5E-113 T 06-07-2017 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 BWK49_RS00920 c12f24d839eb152167c03e77f2f73011 1527 Gene3D G3DSA:3.20.20.70 454 810 1.0E-104 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 BWK49_RS14855 531070fb0945c4fc1cb54916de6de3db 777 Gene3D G3DSA:3.40.50.300 295 497 4.0E-32 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS14855 531070fb0945c4fc1cb54916de6de3db 777 Hamap MF_01973 Lon protease [lon]. 11 767 60.888 T 06-07-2017 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 BWK49_RS14855 531070fb0945c4fc1cb54916de6de3db 777 SMART SM00382 345 489 1.7E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS14855 531070fb0945c4fc1cb54916de6de3db 777 Gene3D G3DSA:3.30.230.10 586 765 1.6E-66 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup BWK49_RS14855 531070fb0945c4fc1cb54916de6de3db 777 Gene3D G3DSA:1.10.8.60 498 580 7.6E-26 T 06-07-2017 BWK49_RS14855 531070fb0945c4fc1cb54916de6de3db 777 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 591 607 1.6E-50 T 06-07-2017 BWK49_RS14855 531070fb0945c4fc1cb54916de6de3db 777 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 698 717 1.6E-50 T 06-07-2017 BWK49_RS14855 531070fb0945c4fc1cb54916de6de3db 777 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 721 739 1.6E-50 T 06-07-2017 BWK49_RS14855 531070fb0945c4fc1cb54916de6de3db 777 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 353 372 1.6E-50 T 06-07-2017 BWK49_RS14855 531070fb0945c4fc1cb54916de6de3db 777 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 668 687 1.6E-50 T 06-07-2017 BWK49_RS14855 531070fb0945c4fc1cb54916de6de3db 777 SUPERFAMILY SSF54211 591 764 7.59E-50 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold BWK49_RS14855 531070fb0945c4fc1cb54916de6de3db 777 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 349 485 4.8E-20 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 BWK49_RS14855 531070fb0945c4fc1cb54916de6de3db 777 TIGRFAM TIGR00763 lon: endopeptidase La 13 765 4.9E-246 T 06-07-2017 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 BWK49_RS14855 531070fb0945c4fc1cb54916de6de3db 777 SUPERFAMILY SSF52540 295 553 3.94E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS14855 531070fb0945c4fc1cb54916de6de3db 777 SMART SM00464 10 192 1.2E-32 T 06-07-2017 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 BWK49_RS14855 531070fb0945c4fc1cb54916de6de3db 777 SUPERFAMILY SSF88697 11 189 9.19E-21 T 06-07-2017 IPR015947 PUA-like domain BWK49_RS14855 531070fb0945c4fc1cb54916de6de3db 777 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 566 767 5.3E-85 T 06-07-2017 IPR008269 Peptidase S16, Lon C-terminal GO:0004176|GO:0004252|GO:0006508 BWK49_RS14855 531070fb0945c4fc1cb54916de6de3db 777 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 671 679 - T 06-07-2017 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 BWK49_RS14855 531070fb0945c4fc1cb54916de6de3db 777 PIRSF PIRSF001174 1 769 5.2E-254 T 06-07-2017 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 BWK49_RS14855 531070fb0945c4fc1cb54916de6de3db 777 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 11 190 1.0E-16 T 06-07-2017 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 BWK49_RS12210 7c4897b37894a0bb22f497e8297f91d7 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 25 36 2.1E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 BWK49_RS12210 7c4897b37894a0bb22f497e8297f91d7 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 36 46 2.1E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 BWK49_RS12210 7c4897b37894a0bb22f497e8297f91d7 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 46 57 2.1E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 BWK49_RS12210 7c4897b37894a0bb22f497e8297f91d7 313 Gene3D G3DSA:3.40.190.10 185 276 7.3E-15 T 06-07-2017 BWK49_RS12210 7c4897b37894a0bb22f497e8297f91d7 313 Gene3D G3DSA:3.40.190.10 99 184 2.4E-10 T 06-07-2017 BWK49_RS12210 7c4897b37894a0bb22f497e8297f91d7 313 SUPERFAMILY SSF53850 97 310 5.52E-32 T 06-07-2017 BWK49_RS12210 7c4897b37894a0bb22f497e8297f91d7 313 Gene3D G3DSA:1.10.10.10 9 92 4.8E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS12210 7c4897b37894a0bb22f497e8297f91d7 313 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 12 68 2.3E-19 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 BWK49_RS12210 7c4897b37894a0bb22f497e8297f91d7 313 SUPERFAMILY SSF46785 9 117 1.26E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS12210 7c4897b37894a0bb22f497e8297f91d7 313 Pfam PF03466 LysR substrate binding domain 95 310 3.4E-40 T 06-07-2017 IPR005119 LysR, substrate-binding BWK49_RS10625 01b6fa6a515e4dc4b4d24271b6f15171 391 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 305 386 2.5E-12 T 06-07-2017 IPR022171 PPE family, C-terminal BWK49_RS10625 01b6fa6a515e4dc4b4d24271b6f15171 391 SUPERFAMILY SSF140459 2 174 7.32E-66 T 06-07-2017 BWK49_RS10625 01b6fa6a515e4dc4b4d24271b6f15171 391 Pfam PF00823 PPE family 5 161 2.1E-63 T 06-07-2017 IPR000030 PPE family BWK49_RS02040 f61876d4c046f0355e34e841c511886f 328 Pfam PF00656 Caspase domain 2 217 4.0E-19 T 06-07-2017 BWK49_RS02040 f61876d4c046f0355e34e841c511886f 328 Gene3D G3DSA:3.40.50.1460 2 133 5.9E-9 T 06-07-2017 IPR029030 Caspase-like domain BWK49_RS02040 f61876d4c046f0355e34e841c511886f 328 SUPERFAMILY SSF52129 2 184 1.48E-16 T 06-07-2017 IPR029030 Caspase-like domain BWK49_RS18255 3cdabfcb74c119adfbe08ee54849caea 261 Gene3D G3DSA:3.20.20.70 3 253 5.8E-102 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 BWK49_RS18255 3cdabfcb74c119adfbe08ee54849caea 261 Pfam PF00121 Triosephosphate isomerase 6 251 1.4E-87 T 06-07-2017 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 BWK49_RS18255 3cdabfcb74c119adfbe08ee54849caea 261 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 3 255 38.884 T 06-07-2017 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 BWK49_RS18255 3cdabfcb74c119adfbe08ee54849caea 261 SUPERFAMILY SSF51351 2 253 6.81E-88 T 06-07-2017 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 BWK49_RS18255 3cdabfcb74c119adfbe08ee54849caea 261 ProSitePatterns PS00171 Triosephosphate isomerase active site. 170 180 - T 06-07-2017 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 BWK49_RS18255 3cdabfcb74c119adfbe08ee54849caea 261 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 6 244 3.7E-56 T 06-07-2017 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 BWK49_RS01805 20361f0bd3d32eaaebdcd822bbd9d367 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.7E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS01805 20361f0bd3d32eaaebdcd822bbd9d367 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 1.7E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS01805 20361f0bd3d32eaaebdcd822bbd9d367 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 239 1.7E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS01805 20361f0bd3d32eaaebdcd822bbd9d367 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 1.7E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS01805 20361f0bd3d32eaaebdcd822bbd9d367 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 1.7E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS01805 20361f0bd3d32eaaebdcd822bbd9d367 272 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS01805 20361f0bd3d32eaaebdcd822bbd9d367 272 SUPERFAMILY SSF51735 2 257 9.08E-58 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS01805 20361f0bd3d32eaaebdcd822bbd9d367 272 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 1.7E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS01805 20361f0bd3d32eaaebdcd822bbd9d367 272 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 1.7E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS01805 20361f0bd3d32eaaebdcd822bbd9d367 272 Gene3D G3DSA:3.40.50.720 2 259 6.0E-61 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS01805 20361f0bd3d32eaaebdcd822bbd9d367 272 Pfam PF00106 short chain dehydrogenase 8 197 3.1E-43 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS07325 cd3514fa0217d065e4f87d875b55e161 151 Gene3D G3DSA:3.40.50.2000 56 144 1.4E-12 T 06-07-2017 BWK49_RS07325 cd3514fa0217d065e4f87d875b55e161 151 Pfam PF08660 Oligosaccharide biosynthesis protein Alg14 like 57 150 1.5E-18 T 06-07-2017 IPR013969 Oligosaccharide biosynthesis protein Alg14-like Reactome: R-HSA-446193|Reactome: R-HSA-5633231 BWK49_RS07325 cd3514fa0217d065e4f87d875b55e161 151 SUPERFAMILY SSF53756 4 144 4.81E-12 T 06-07-2017 BWK49_RS09370 85b91565c9b785ce2a4502adcb86e98a 280 SUPERFAMILY SSF51735 1 263 1.43E-60 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS09370 85b91565c9b785ce2a4502adcb86e98a 280 Gene3D G3DSA:3.40.50.720 5 237 1.9E-60 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS09370 85b91565c9b785ce2a4502adcb86e98a 280 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 1.4E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS09370 85b91565c9b785ce2a4502adcb86e98a 280 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 1.4E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS09370 85b91565c9b785ce2a4502adcb86e98a 280 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 1.4E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS09370 85b91565c9b785ce2a4502adcb86e98a 280 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS09370 85b91565c9b785ce2a4502adcb86e98a 280 Pfam PF00106 short chain dehydrogenase 7 202 3.7E-44 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS09370 85b91565c9b785ce2a4502adcb86e98a 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 2.2E-20 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS09370 85b91565c9b785ce2a4502adcb86e98a 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 2.2E-20 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS09370 85b91565c9b785ce2a4502adcb86e98a 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 2.2E-20 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS09370 85b91565c9b785ce2a4502adcb86e98a 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 2.2E-20 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS09370 85b91565c9b785ce2a4502adcb86e98a 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 2.2E-20 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS26480 65486c0e19055f347be8db1dc99dce96 78 Pfam PF00830 Ribosomal L28 family 4 61 2.4E-23 T 06-07-2017 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS26480 65486c0e19055f347be8db1dc99dce96 78 SUPERFAMILY SSF143800 2 75 5.49E-26 T 06-07-2017 BWK49_RS26480 65486c0e19055f347be8db1dc99dce96 78 TIGRFAM TIGR00009 L28: ribosomal protein bL28 2 57 9.5E-24 T 06-07-2017 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS26480 65486c0e19055f347be8db1dc99dce96 78 Gene3D G3DSA:2.30.170.40 2 75 1.5E-30 T 06-07-2017 BWK49_RS26480 65486c0e19055f347be8db1dc99dce96 78 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 67 20.77 T 06-07-2017 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS13725 3ccc2edb69ca6fcfdefaf3583a0a5fbd 164 SUPERFAMILY SSF52540 7 161 3.55E-22 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS13725 3ccc2edb69ca6fcfdefaf3583a0a5fbd 164 Pfam PF01202 Shikimate kinase 13 161 4.6E-13 T 06-07-2017 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 BWK49_RS13725 3ccc2edb69ca6fcfdefaf3583a0a5fbd 164 Gene3D G3DSA:3.40.50.300 7 162 7.5E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS13725 3ccc2edb69ca6fcfdefaf3583a0a5fbd 164 TIGRFAM TIGR01313 therm_gnt_kin: carbohydrate kinase, thermoresistant glucokinase family 7 159 2.9E-55 T 06-07-2017 IPR006001 Carbohydrate kinase, thermoresistant glucokinase GO:0005975|GO:0016301 KEGG: 00030+2.7.1.12|MetaCyc: PWY-5530 BWK49_RS12025 2166c5b02cb0871d0055c8e3fb0e505e 376 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 155 1.7E-27 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 BWK49_RS12025 2166c5b02cb0871d0055c8e3fb0e505e 376 SMART SM00829 10 368 0.0039 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 BWK49_RS12025 2166c5b02cb0871d0055c8e3fb0e505e 376 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 61 75 - T 06-07-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 BWK49_RS12025 2166c5b02cb0871d0055c8e3fb0e505e 376 SUPERFAMILY SSF50129 322 370 1.37E-8 T 06-07-2017 IPR011032 GroES-like BWK49_RS12025 2166c5b02cb0871d0055c8e3fb0e505e 376 SUPERFAMILY SSF50129 1 180 1.56E-57 T 06-07-2017 IPR011032 GroES-like BWK49_RS12025 2166c5b02cb0871d0055c8e3fb0e505e 376 Pfam PF00107 Zinc-binding dehydrogenase 197 326 5.1E-17 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 BWK49_RS12025 2166c5b02cb0871d0055c8e3fb0e505e 376 SUPERFAMILY SSF51735 159 332 2.79E-29 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS12025 2166c5b02cb0871d0055c8e3fb0e505e 376 Gene3D G3DSA:3.90.180.10 2 189 8.2E-58 T 06-07-2017 IPR011032 GroES-like BWK49_RS12025 2166c5b02cb0871d0055c8e3fb0e505e 376 TIGRFAM TIGR03989 Rxyl_3153: NDMA-dependent alcohol dehydrogenase, Rxyl_3153 family 2 370 6.7E-165 T 06-07-2017 IPR023921 Alcohol dehydrogenase, zinc-type, actinomycetes KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396 BWK49_RS12025 2166c5b02cb0871d0055c8e3fb0e505e 376 Gene3D G3DSA:3.40.50.720 190 312 2.1E-21 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS10000 c6128ffd18d55135bf6c213f58544c6f 510 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 4 339 2.0E-122 T 06-07-2017 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 BWK49_RS10000 c6128ffd18d55135bf6c213f58544c6f 510 Pfam PF09269 Domain of unknown function (DUF1967) 366 436 9.2E-25 T 06-07-2017 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 BWK49_RS10000 c6128ffd18d55135bf6c213f58544c6f 510 Pfam PF01018 GTP1/OBG 4 157 1.4E-51 T 06-07-2017 IPR006169 GTP1/OBG domain GO:0005525 BWK49_RS10000 c6128ffd18d55135bf6c213f58544c6f 510 SUPERFAMILY SSF102741 365 438 8.76E-21 T 06-07-2017 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 BWK49_RS10000 c6128ffd18d55135bf6c213f58544c6f 510 TIGRFAM TIGR03595 Obg_CgtA_exten: Obg family GTPase CgtA, C-terminal extension 373 437 8.8E-25 T 06-07-2017 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 BWK49_RS10000 c6128ffd18d55135bf6c213f58544c6f 510 Gene3D G3DSA:3.40.50.300 160 344 6.8E-49 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS10000 c6128ffd18d55135bf6c213f58544c6f 510 SUPERFAMILY SSF82051 4 157 6.41E-47 T 06-07-2017 IPR006169 GTP1/OBG domain GO:0005525 BWK49_RS10000 c6128ffd18d55135bf6c213f58544c6f 510 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 227 245 9.4E-35 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 BWK49_RS10000 c6128ffd18d55135bf6c213f58544c6f 510 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 210 225 9.4E-35 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 BWK49_RS10000 c6128ffd18d55135bf6c213f58544c6f 510 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 183 201 9.4E-35 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 BWK49_RS10000 c6128ffd18d55135bf6c213f58544c6f 510 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 162 182 9.4E-35 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 BWK49_RS10000 c6128ffd18d55135bf6c213f58544c6f 510 Pfam PF01926 50S ribosome-binding GTPase 162 293 3.6E-21 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 BWK49_RS10000 c6128ffd18d55135bf6c213f58544c6f 510 ProSitePatterns PS00905 GTP1/OBG family signature. 212 225 - T 06-07-2017 IPR006074 GTP1/OBG, conserved site GO:0005525 BWK49_RS10000 c6128ffd18d55135bf6c213f58544c6f 510 SUPERFAMILY SSF52540 162 359 1.92E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS10000 c6128ffd18d55135bf6c213f58544c6f 510 Hamap MF_01454 GTPase Obg [obg]. 3 340 43.6 T 06-07-2017 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 BWK49_RS10000 c6128ffd18d55135bf6c213f58544c6f 510 Gene3D G3DSA:2.70.210.12 3 156 2.6E-48 T 06-07-2017 IPR006169 GTP1/OBG domain GO:0005525 BWK49_RS00890 39df4782387fc79ae5f285c6f710c964 624 PRINTS PR00819 CbxX/CfqX superfamily signature 425 444 7.9E-46 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 BWK49_RS00890 39df4782387fc79ae5f285c6f710c964 624 PRINTS PR00819 CbxX/CfqX superfamily signature 411 425 7.9E-46 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 BWK49_RS00890 39df4782387fc79ae5f285c6f710c964 624 PRINTS PR00819 CbxX/CfqX superfamily signature 459 471 7.9E-46 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 BWK49_RS00890 39df4782387fc79ae5f285c6f710c964 624 PRINTS PR00819 CbxX/CfqX superfamily signature 333 347 7.9E-46 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 BWK49_RS00890 39df4782387fc79ae5f285c6f710c964 624 PRINTS PR00819 CbxX/CfqX superfamily signature 497 516 7.9E-46 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 BWK49_RS00890 39df4782387fc79ae5f285c6f710c964 624 PRINTS PR00819 CbxX/CfqX superfamily signature 373 388 7.9E-46 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 BWK49_RS00890 39df4782387fc79ae5f285c6f710c964 624 PRINTS PR00819 CbxX/CfqX superfamily signature 563 575 7.9E-46 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 BWK49_RS00890 39df4782387fc79ae5f285c6f710c964 624 PRINTS PR00819 CbxX/CfqX superfamily signature 480 497 7.9E-46 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 BWK49_RS00890 39df4782387fc79ae5f285c6f710c964 624 TIGRFAM TIGR03922 T7SS_EccA: type VII secretion AAA-ATPase EccA 42 614 2.8E-247 T 06-07-2017 IPR023835 Type VII secretion system AAA-ATPase, EccA BWK49_RS00890 39df4782387fc79ae5f285c6f710c964 624 Gene3D G3DSA:3.40.50.300 338 524 7.8E-23 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS00890 39df4782387fc79ae5f285c6f710c964 624 SUPERFAMILY SSF52540 344 598 3.01E-33 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS00890 39df4782387fc79ae5f285c6f710c964 624 SMART SM00382 370 512 1.5E-5 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS00890 39df4782387fc79ae5f285c6f710c964 624 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 374 509 6.5E-18 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 BWK49_RS27230 03ad65c7ce0bd29cdfc4ce3517221cf5 323 Pfam PF06271 RDD family 22 144 5.5E-11 T 06-07-2017 IPR010432 RDD BWK49_RS27730 48b29f1eb0b20e39dfdf2bfbdb70ae18 309 Gene3D G3DSA:1.10.10.10 3 85 5.1E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS27730 48b29f1eb0b20e39dfdf2bfbdb70ae18 309 SUPERFAMILY SSF53850 88 292 6.83E-30 T 06-07-2017 BWK49_RS27730 48b29f1eb0b20e39dfdf2bfbdb70ae18 309 Gene3D G3DSA:3.40.190.10 187 263 9.3E-10 T 06-07-2017 BWK49_RS27730 48b29f1eb0b20e39dfdf2bfbdb70ae18 309 Pfam PF03466 LysR substrate binding domain 87 287 2.5E-31 T 06-07-2017 IPR005119 LysR, substrate-binding BWK49_RS27730 48b29f1eb0b20e39dfdf2bfbdb70ae18 309 SUPERFAMILY SSF46785 3 87 1.09E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS27730 48b29f1eb0b20e39dfdf2bfbdb70ae18 309 Gene3D G3DSA:3.40.190.10 89 186 4.6E-14 T 06-07-2017 BWK49_RS27730 48b29f1eb0b20e39dfdf2bfbdb70ae18 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.6E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 BWK49_RS27730 48b29f1eb0b20e39dfdf2bfbdb70ae18 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.6E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 BWK49_RS27730 48b29f1eb0b20e39dfdf2bfbdb70ae18 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.6E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 BWK49_RS27730 48b29f1eb0b20e39dfdf2bfbdb70ae18 309 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 2.2E-19 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 BWK49_RS09745 31fa685ada44dd35ee2b1d4ed4fd13f4 273 PIRSF PIRSF015582 1 271 4.4E-73 T 06-07-2017 IPR011206 Citrate lyase beta subunit-like BWK49_RS09745 31fa685ada44dd35ee2b1d4ed4fd13f4 273 SUPERFAMILY SSF51621 9 223 1.15E-61 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 BWK49_RS09745 31fa685ada44dd35ee2b1d4ed4fd13f4 273 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 11 211 1.3E-26 T 06-07-2017 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 BWK49_RS09745 31fa685ada44dd35ee2b1d4ed4fd13f4 273 Gene3D G3DSA:3.20.20.60 9 223 2.6E-66 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 BWK49_RS28785 e766f1efaee343d386ca077d9c553c13 366 Gene3D G3DSA:1.10.443.10 135 335 3.7E-36 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 BWK49_RS28785 e766f1efaee343d386ca077d9c553c13 366 Pfam PF00589 Phage integrase family 140 328 3.1E-24 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 BWK49_RS28785 e766f1efaee343d386ca077d9c553c13 366 Gene3D G3DSA:1.10.150.130 25 120 1.8E-9 T 06-07-2017 IPR023109 Integrase/recombinase, N-terminal BWK49_RS28785 e766f1efaee343d386ca077d9c553c13 366 SUPERFAMILY SSF56349 24 337 9.71E-43 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 BWK49_RS19635 e924da8aa361015d42f7f9652147ae6f 177 Pfam PF00583 Acetyltransferase (GNAT) family 59 131 9.2E-12 T 06-07-2017 IPR000182 GNAT domain GO:0008080 BWK49_RS19635 e924da8aa361015d42f7f9652147ae6f 177 SUPERFAMILY SSF55729 18 135 1.89E-21 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase BWK49_RS19635 e924da8aa361015d42f7f9652147ae6f 177 Gene3D G3DSA:3.40.630.30 18 154 1.1E-27 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase BWK49_RS21155 dc9e9b9c465218d214f9dc19de75816f 241 SUPERFAMILY SSF53335 12 230 1.72E-37 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS21155 dc9e9b9c465218d214f9dc19de75816f 241 Gene3D G3DSA:3.40.50.150 12 224 3.2E-29 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS21155 dc9e9b9c465218d214f9dc19de75816f 241 Pfam PF01209 ubiE/COQ5 methyltransferase family 43 224 6.5E-21 T 06-07-2017 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 BWK49_RS21615 87497632a9751e5e7a38297adb517626 393 Gene3D G3DSA:1.20.1250.20 4 171 9.2E-35 T 06-07-2017 BWK49_RS21615 87497632a9751e5e7a38297adb517626 393 Gene3D G3DSA:1.20.1250.20 183 370 7.7E-30 T 06-07-2017 BWK49_RS21615 87497632a9751e5e7a38297adb517626 393 ProSitePatterns PS00216 Sugar transport proteins signature 1. 246 262 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 BWK49_RS21615 87497632a9751e5e7a38297adb517626 393 Pfam PF07690 Major Facilitator Superfamily 2 222 2.7E-29 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 BWK49_RS21615 87497632a9751e5e7a38297adb517626 393 PRINTS PR01035 Tetracycline resistance protein signature 1 15 1.1E-13 T 06-07-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 BWK49_RS21615 87497632a9751e5e7a38297adb517626 393 PRINTS PR01035 Tetracycline resistance protein signature 116 138 1.1E-13 T 06-07-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 BWK49_RS21615 87497632a9751e5e7a38297adb517626 393 PRINTS PR01035 Tetracycline resistance protein signature 255 276 1.1E-13 T 06-07-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 BWK49_RS21615 87497632a9751e5e7a38297adb517626 393 PRINTS PR01035 Tetracycline resistance protein signature 27 46 1.1E-13 T 06-07-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 BWK49_RS21615 87497632a9751e5e7a38297adb517626 393 SUPERFAMILY SSF103473 2 376 6.02E-67 T 06-07-2017 IPR020846 Major facilitator superfamily domain BWK49_RS26880 34e6ce2f5c912d2b577db13a21df3133 565 Gene3D G3DSA:2.40.110.10 130 199 2.4E-9 T 06-07-2017 BWK49_RS26880 34e6ce2f5c912d2b577db13a21df3133 565 SUPERFAMILY SSF56645 15 198 1.7E-20 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS26880 34e6ce2f5c912d2b577db13a21df3133 565 Gene3D G3DSA:1.20.140.10 217 384 2.4E-16 T 06-07-2017 BWK49_RS26880 34e6ce2f5c912d2b577db13a21df3133 565 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 235 382 8.2E-13 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS26880 34e6ce2f5c912d2b577db13a21df3133 565 SUPERFAMILY SSF47203 234 387 9.18E-23 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS08390 9acc7457904755395023fff4e76361d5 389 SUPERFAMILY SSF53901 255 378 1.32E-12 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS08390 9acc7457904755395023fff4e76361d5 389 SUPERFAMILY SSF53901 7 232 5.32E-24 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS08390 9acc7457904755395023fff4e76361d5 389 PIRSF PIRSF000429 6 340 2.6E-20 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 BWK49_RS08390 9acc7457904755395023fff4e76361d5 389 Gene3D G3DSA:3.40.47.10 201 229 2.5E-11 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS08390 9acc7457904755395023fff4e76361d5 389 Gene3D G3DSA:3.40.47.10 12 115 2.5E-11 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS02310 518f512d788ae05177560d947923237e 292 PRINTS PR00990 Ribokinase signature 32 51 4.6E-11 T 06-07-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 BWK49_RS02310 518f512d788ae05177560d947923237e 292 PRINTS PR00990 Ribokinase signature 5 26 4.6E-11 T 06-07-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 BWK49_RS02310 518f512d788ae05177560d947923237e 292 PRINTS PR00990 Ribokinase signature 168 183 4.6E-11 T 06-07-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 BWK49_RS02310 518f512d788ae05177560d947923237e 292 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 37 61 - T 06-07-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 BWK49_RS02310 518f512d788ae05177560d947923237e 292 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 241 254 - T 06-07-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 BWK49_RS02310 518f512d788ae05177560d947923237e 292 Pfam PF00294 pfkB family carbohydrate kinase 3 286 6.1E-41 T 06-07-2017 IPR011611 Carbohydrate kinase PfkB BWK49_RS02310 518f512d788ae05177560d947923237e 292 SUPERFAMILY SSF53613 1 287 5.3E-56 T 06-07-2017 IPR029056 Ribokinase-like BWK49_RS02310 518f512d788ae05177560d947923237e 292 Gene3D G3DSA:3.40.1190.20 3 291 2.7E-58 T 06-07-2017 IPR029056 Ribokinase-like BWK49_RS12865 c8845a24a795e2114eaa486e13189336 652 Pfam PF13537 Glutamine amidotransferase domain 59 181 1.9E-37 T 06-07-2017 IPR017932 Glutamine amidotransferase type 2 domain BWK49_RS12865 c8845a24a795e2114eaa486e13189336 652 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 568 2.0E-140 T 06-07-2017 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 BWK49_RS12865 c8845a24a795e2114eaa486e13189336 652 SUPERFAMILY SSF56235 2 233 5.06E-55 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal BWK49_RS12865 c8845a24a795e2114eaa486e13189336 652 Pfam PF00733 Asparagine synthase 262 631 1.0E-108 T 06-07-2017 IPR001962 Asparagine synthase GO:0004066|GO:0006529 BWK49_RS12865 c8845a24a795e2114eaa486e13189336 652 SUPERFAMILY SSF52402 250 401 3.49E-85 T 06-07-2017 BWK49_RS12865 c8845a24a795e2114eaa486e13189336 652 SUPERFAMILY SSF52402 488 627 3.49E-85 T 06-07-2017 BWK49_RS12865 c8845a24a795e2114eaa486e13189336 652 PIRSF PIRSF001589 1 647 1.3E-168 T 06-07-2017 BWK49_RS12865 c8845a24a795e2114eaa486e13189336 652 Gene3D G3DSA:3.40.50.620 483 631 6.8E-97 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold BWK49_RS12865 c8845a24a795e2114eaa486e13189336 652 Gene3D G3DSA:3.40.50.620 242 397 6.8E-97 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold BWK49_RS12865 c8845a24a795e2114eaa486e13189336 652 Gene3D G3DSA:3.60.20.10 2 241 3.7E-69 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal BWK49_RS04875 2c7e326d9becffa7cdc052140691ef78 118 Pfam PF13276 HTH-like domain 38 79 5.1E-10 T 06-07-2017 IPR025948 HTH-like domain BWK49_RS28150 6bd4753775c3b559abba589393f5c981 198 SUPERFAMILY SSF46689 16 84 6.62E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS28150 6bd4753775c3b559abba589393f5c981 198 Gene3D G3DSA:1.10.357.10 66 197 5.0E-15 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS28150 6bd4753775c3b559abba589393f5c981 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 71 3.9E-12 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS28150 6bd4753775c3b559abba589393f5c981 198 Gene3D G3DSA:1.10.10.60 16 64 2.5E-23 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS28150 6bd4753775c3b559abba589393f5c981 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 47 70 6.6E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS28150 6bd4753775c3b559abba589393f5c981 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 39 6.6E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS28150 6bd4753775c3b559abba589393f5c981 198 SUPERFAMILY SSF48498 87 197 6.37E-13 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS28150 6bd4753775c3b559abba589393f5c981 198 Pfam PF16859 Bacterial transcriptional repressor C-terminal 87 189 4.1E-10 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS15460 82e10e426c8c05c7e69c15bdf6178270 299 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 162 181 2.2E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15460 82e10e426c8c05c7e69c15bdf6178270 299 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 143 151 2.2E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15460 82e10e426c8c05c7e69c15bdf6178270 299 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 88 99 2.2E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15460 82e10e426c8c05c7e69c15bdf6178270 299 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 137 153 9.9E-27 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15460 82e10e426c8c05c7e69c15bdf6178270 299 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 9.9E-27 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15460 82e10e426c8c05c7e69c15bdf6178270 299 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 9.9E-27 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15460 82e10e426c8c05c7e69c15bdf6178270 299 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 224 244 9.9E-27 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15460 82e10e426c8c05c7e69c15bdf6178270 299 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 181 9.9E-27 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15460 82e10e426c8c05c7e69c15bdf6178270 299 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 183 200 9.9E-27 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15460 82e10e426c8c05c7e69c15bdf6178270 299 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 149 177 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS15460 82e10e426c8c05c7e69c15bdf6178270 299 Gene3D G3DSA:3.40.50.720 9 267 4.2E-63 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS15460 82e10e426c8c05c7e69c15bdf6178270 299 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 21 260 1.6E-42 T 06-07-2017 BWK49_RS15460 82e10e426c8c05c7e69c15bdf6178270 299 SUPERFAMILY SSF51735 11 260 1.03E-56 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS10895 05ca813eb6bac6ea737533232a631191 412 Pfam PF14863 Alkyl sulfatase dimerisation 289 402 1.6E-15 T 06-07-2017 IPR029228 Alkyl sulfatase dimerisation domain GO:0046983 BWK49_RS10895 05ca813eb6bac6ea737533232a631191 412 SUPERFAMILY SSF56281 21 401 1.97E-65 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS10895 05ca813eb6bac6ea737533232a631191 412 Pfam PF00753 Metallo-beta-lactamase superfamily 33 242 4.6E-9 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS10895 05ca813eb6bac6ea737533232a631191 412 Gene3D G3DSA:3.60.15.10 149 272 7.3E-38 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS10895 05ca813eb6bac6ea737533232a631191 412 Gene3D G3DSA:3.60.15.10 23 111 7.3E-38 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS10895 05ca813eb6bac6ea737533232a631191 412 SMART SM00849 35 242 4.3E-13 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS08695 de5492646e1751b3643424e17022d6d3 343 SUPERFAMILY SSF51679 2 318 3.79E-73 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS08695 de5492646e1751b3643424e17022d6d3 343 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 3 340 8.2E-117 T 06-07-2017 IPR019949 Luciferase family oxidoreductase, group 1 BWK49_RS08695 de5492646e1751b3643424e17022d6d3 343 Gene3D G3DSA:3.20.20.30 2 342 7.8E-83 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS08695 de5492646e1751b3643424e17022d6d3 343 Pfam PF00296 Luciferase-like monooxygenase 5 304 2.0E-39 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS06280 ca0076f145632e4eda0684e949ea936b 230 Pfam PF00881 Nitroreductase family 14 183 6.5E-31 T 06-07-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 BWK49_RS06280 ca0076f145632e4eda0684e949ea936b 230 Gene3D G3DSA:3.40.109.10 5 204 3.8E-41 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 BWK49_RS06280 ca0076f145632e4eda0684e949ea936b 230 SUPERFAMILY SSF55469 114 206 9.29E-43 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 BWK49_RS06280 ca0076f145632e4eda0684e949ea936b 230 SUPERFAMILY SSF55469 7 68 9.29E-43 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 BWK49_RS04560 d3e8c9f4d86a32efd6bbc45bf0c27e5f 497 SUPERFAMILY SSF56349 338 400 4.71E-12 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 BWK49_RS04560 d3e8c9f4d86a32efd6bbc45bf0c27e5f 497 SUPERFAMILY SSF56349 429 457 4.71E-12 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 BWK49_RS04560 d3e8c9f4d86a32efd6bbc45bf0c27e5f 497 SUPERFAMILY SSF56349 216 290 4.71E-12 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 BWK49_RS04560 d3e8c9f4d86a32efd6bbc45bf0c27e5f 497 Gene3D G3DSA:1.10.150.130 56 153 2.2E-9 T 06-07-2017 IPR023109 Integrase/recombinase, N-terminal BWK49_RS04560 d3e8c9f4d86a32efd6bbc45bf0c27e5f 497 Gene3D G3DSA:1.10.443.10 217 304 9.5E-17 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 BWK49_RS04560 d3e8c9f4d86a32efd6bbc45bf0c27e5f 497 Gene3D G3DSA:1.10.443.10 351 457 9.5E-17 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 BWK49_RS04560 d3e8c9f4d86a32efd6bbc45bf0c27e5f 497 SUPERFAMILY SSF47823 55 153 4.51E-5 T 06-07-2017 IPR010998 Integrase, Lambda-type, N-terminal BWK49_RS04560 d3e8c9f4d86a32efd6bbc45bf0c27e5f 497 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 57 146 2.8E-6 T 06-07-2017 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 BWK49_RS19280 a9b24b8551f11e4ba8c69d903fd29ea6 141 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 13 139 1.3E-48 T 06-07-2017 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 BWK49_RS19280 a9b24b8551f11e4ba8c69d903fd29ea6 141 Pfam PF01641 SelR domain 17 137 1.7E-52 T 06-07-2017 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 BWK49_RS19280 a9b24b8551f11e4ba8c69d903fd29ea6 141 Gene3D G3DSA:2.170.150.20 9 139 9.4E-60 T 06-07-2017 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 BWK49_RS19280 a9b24b8551f11e4ba8c69d903fd29ea6 141 SUPERFAMILY SSF51316 11 139 1.78E-55 T 06-07-2017 IPR011057 Mss4-like BWK49_RS08070 4ad89effa5cec0116824cb2a412ab94e 385 SUPERFAMILY SSF56645 2 247 9.16E-74 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS08070 4ad89effa5cec0116824cb2a412ab94e 385 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 130 142 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 BWK49_RS08070 4ad89effa5cec0116824cb2a412ab94e 385 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 123 1.3E-22 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS08070 4ad89effa5cec0116824cb2a412ab94e 385 Gene3D G3DSA:1.20.140.10 223 385 6.3E-24 T 06-07-2017 BWK49_RS08070 4ad89effa5cec0116824cb2a412ab94e 385 SUPERFAMILY SSF47203 234 384 1.77E-16 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS08070 4ad89effa5cec0116824cb2a412ab94e 385 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 234 380 1.6E-17 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS08070 4ad89effa5cec0116824cb2a412ab94e 385 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 128 222 3.2E-20 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 BWK49_RS08070 4ad89effa5cec0116824cb2a412ab94e 385 Gene3D G3DSA:1.10.540.10 2 124 8.0E-26 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS08070 4ad89effa5cec0116824cb2a412ab94e 385 Gene3D G3DSA:2.40.110.10 127 222 3.7E-37 T 06-07-2017 BWK49_RS25225 c0fca38ac567b9c7a552347125450cce 212 SUPERFAMILY SSF52266 23 208 6.87E-26 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain BWK49_RS25225 c0fca38ac567b9c7a552347125450cce 212 Gene3D G3DSA:3.40.50.1110 24 209 5.9E-19 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain BWK49_RS25225 c0fca38ac567b9c7a552347125450cce 212 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 26 196 2.1E-16 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain BWK49_RS20010 71f4df3ad161286b7e1b8efaf0e07117 374 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 39 359 9.0E-37 T 06-07-2017 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 BWK49_RS20010 71f4df3ad161286b7e1b8efaf0e07117 374 Gene3D G3DSA:3.40.720.10 24 302 4.1E-43 T 06-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 BWK49_RS20010 71f4df3ad161286b7e1b8efaf0e07117 374 SUPERFAMILY SSF53649 37 374 1.8E-55 T 06-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 BWK49_RS08495 8d2fd4db4db060552b2d845f6edca518 404 ProSitePatterns PS00809 ADP-glucose pyrophosphorylase signature 2. 98 106 - T 06-07-2017 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 BWK49_RS08495 8d2fd4db4db060552b2d845f6edca518 404 Pfam PF00483 Nucleotidyl transferase 9 276 5.2E-72 T 06-07-2017 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 BWK49_RS08495 8d2fd4db4db060552b2d845f6edca518 404 ProSitePatterns PS00810 ADP-glucose pyrophosphorylase signature 3. 196 206 - T 06-07-2017 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 BWK49_RS08495 8d2fd4db4db060552b2d845f6edca518 404 ProSitePatterns PS00808 ADP-glucose pyrophosphorylase signature 1. 13 32 - T 06-07-2017 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 BWK49_RS08495 8d2fd4db4db060552b2d845f6edca518 404 SUPERFAMILY SSF51161 301 398 6.94E-17 T 06-07-2017 IPR011004 Trimeric LpxA-like BWK49_RS08495 8d2fd4db4db060552b2d845f6edca518 404 TIGRFAM TIGR02091 glgC: glucose-1-phosphate adenylyltransferase 7 378 3.6E-144 T 06-07-2017 IPR011831 Glucose-1-phosphate adenylyltransferase GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 BWK49_RS08495 8d2fd4db4db060552b2d845f6edca518 404 SUPERFAMILY SSF53448 342 359 1.97E-71 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases BWK49_RS08495 8d2fd4db4db060552b2d845f6edca518 404 SUPERFAMILY SSF53448 7 280 1.97E-71 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases BWK49_RS08495 8d2fd4db4db060552b2d845f6edca518 404 Hamap MF_00624 Glucose-1-phosphate adenylyltransferase [glgC]. 4 404 47.18 T 06-07-2017 IPR023049 Glucose-1-phosphate adenylyltransferase GlgC, bacterial GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 BWK49_RS08495 8d2fd4db4db060552b2d845f6edca518 404 Gene3D G3DSA:3.90.550.10 325 368 3.5E-74 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases BWK49_RS08495 8d2fd4db4db060552b2d845f6edca518 404 Gene3D G3DSA:3.90.550.10 9 287 3.5E-74 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases BWK49_RS15510 0eb1834a0de58b0fe1599fd089538e0c 411 Pfam PF01321 Creatinase/Prolidase N-terminal domain 29 137 2.3E-5 T 06-07-2017 IPR000587 Creatinase, N-terminal GO:0016787 BWK49_RS15510 0eb1834a0de58b0fe1599fd089538e0c 411 Gene3D G3DSA:3.90.230.10 167 406 2.3E-40 T 06-07-2017 IPR000994 Peptidase M24, structural domain BWK49_RS15510 0eb1834a0de58b0fe1599fd089538e0c 411 SUPERFAMILY SSF53092 29 157 9.94E-12 T 06-07-2017 IPR028980 Creatinase/Aminopeptidase P, N-terminal BWK49_RS15510 0eb1834a0de58b0fe1599fd089538e0c 411 Pfam PF00557 Metallopeptidase family M24 176 395 1.7E-30 T 06-07-2017 IPR000994 Peptidase M24, structural domain BWK49_RS15510 0eb1834a0de58b0fe1599fd089538e0c 411 Gene3D G3DSA:3.40.350.10 29 152 1.7E-12 T 06-07-2017 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal BWK49_RS15510 0eb1834a0de58b0fe1599fd089538e0c 411 SUPERFAMILY SSF55920 167 408 1.16E-46 T 06-07-2017 IPR000994 Peptidase M24, structural domain BWK49_RS22675 e11cb5153a6bffd02effb13b2a622292 395 Gene3D G3DSA:3.40.250.10 288 389 9.8E-28 T 06-07-2017 IPR001763 Rhodanese-like domain BWK49_RS22675 e11cb5153a6bffd02effb13b2a622292 395 Pfam PF00899 ThiF family 25 261 1.3E-55 T 06-07-2017 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 BWK49_RS22675 e11cb5153a6bffd02effb13b2a622292 395 SMART SM00450 293 390 4.5E-23 T 06-07-2017 IPR001763 Rhodanese-like domain BWK49_RS22675 e11cb5153a6bffd02effb13b2a622292 395 Pfam PF00581 Rhodanese-like domain 293 386 4.5E-14 T 06-07-2017 IPR001763 Rhodanese-like domain BWK49_RS22675 e11cb5153a6bffd02effb13b2a622292 395 Gene3D G3DSA:3.40.50.720 19 261 7.1E-66 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS22675 e11cb5153a6bffd02effb13b2a622292 395 SUPERFAMILY SSF69572 12 362 1.7E-91 T 06-07-2017 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 BWK49_RS08310 7819e62ae21f793fc7d600f5982c8aa5 108 Gene3D G3DSA:3.30.70.20 4 79 1.3E-18 T 06-07-2017 BWK49_RS08310 7819e62ae21f793fc7d600f5982c8aa5 108 Pfam PF00037 4Fe-4S binding domain 34 56 1.2E-8 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain BWK49_RS08310 7819e62ae21f793fc7d600f5982c8aa5 108 PRINTS PR00354 7Fe ferredoxin signature 9 19 4.7E-18 T 06-07-2017 IPR000813 7Fe ferredoxin GO:0009055 BWK49_RS08310 7819e62ae21f793fc7d600f5982c8aa5 108 PRINTS PR00354 7Fe ferredoxin signature 19 29 4.7E-18 T 06-07-2017 IPR000813 7Fe ferredoxin GO:0009055 BWK49_RS08310 7819e62ae21f793fc7d600f5982c8aa5 108 PRINTS PR00354 7Fe ferredoxin signature 35 52 4.7E-18 T 06-07-2017 IPR000813 7Fe ferredoxin GO:0009055 BWK49_RS08310 7819e62ae21f793fc7d600f5982c8aa5 108 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site BWK49_RS08310 7819e62ae21f793fc7d600f5982c8aa5 108 SUPERFAMILY SSF54862 4 83 1.17E-19 T 06-07-2017 BWK49_RS07420 8ea400af4b7e8c7f4a5d1e046c55d55d 306 Gene3D G3DSA:3.30.230.10 6 161 3.2E-53 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup BWK49_RS07420 8ea400af4b7e8c7f4a5d1e046c55d55d 306 Pfam PF08544 GHMP kinases C terminal 207 274 2.9E-8 T 06-07-2017 IPR013750 GHMP kinase, C-terminal domain BWK49_RS07420 8ea400af4b7e8c7f4a5d1e046c55d55d 306 SUPERFAMILY SSF54211 5 159 3.64E-43 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold BWK49_RS07420 8ea400af4b7e8c7f4a5d1e046c55d55d 306 Hamap MF_00061 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 6 292 30.923 T 06-07-2017 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 BWK49_RS07420 8ea400af4b7e8c7f4a5d1e046c55d55d 306 Gene3D G3DSA:3.30.70.890 167 283 1.8E-19 T 06-07-2017 IPR013750 GHMP kinase, C-terminal domain BWK49_RS07420 8ea400af4b7e8c7f4a5d1e046c55d55d 306 SUPERFAMILY SSF55060 167 286 6.33E-19 T 06-07-2017 IPR013750 GHMP kinase, C-terminal domain BWK49_RS07420 8ea400af4b7e8c7f4a5d1e046c55d55d 306 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 6 271 4.4E-52 T 06-07-2017 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 BWK49_RS07420 8ea400af4b7e8c7f4a5d1e046c55d55d 306 Pfam PF00288 GHMP kinases N terminal domain 91 148 5.7E-8 T 06-07-2017 IPR006204 GHMP kinase N-terminal domain GO:0005524 BWK49_RS07420 8ea400af4b7e8c7f4a5d1e046c55d55d 306 PIRSF PIRSF010376 4 299 8.7E-81 T 06-07-2017 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 BWK49_RS09995 299650dfccb0f4da9b6ef62ad2d896d0 88 Gene3D G3DSA:2.40.50.100 20 81 1.4E-27 T 06-07-2017 BWK49_RS09995 299650dfccb0f4da9b6ef62ad2d896d0 88 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 28 69 6.0E-16 T 06-07-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS09995 299650dfccb0f4da9b6ef62ad2d896d0 88 PRINTS PR00063 Ribosomal protein L27 signature 29 53 3.5E-35 T 06-07-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS09995 299650dfccb0f4da9b6ef62ad2d896d0 88 PRINTS PR00063 Ribosomal protein L27 signature 4 28 3.5E-35 T 06-07-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS09995 299650dfccb0f4da9b6ef62ad2d896d0 88 PRINTS PR00063 Ribosomal protein L27 signature 54 78 3.5E-35 T 06-07-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS09995 299650dfccb0f4da9b6ef62ad2d896d0 88 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 1 83 26.805 T 06-07-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS09995 299650dfccb0f4da9b6ef62ad2d896d0 88 TIGRFAM TIGR00062 L27: ribosomal protein bL27 1 81 7.7E-35 T 06-07-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS09995 299650dfccb0f4da9b6ef62ad2d896d0 88 Pfam PF01016 Ribosomal L27 protein 2 80 1.1E-34 T 06-07-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS09995 299650dfccb0f4da9b6ef62ad2d896d0 88 SUPERFAMILY SSF110324 2 81 1.71E-30 T 06-07-2017 BWK49_RS09995 299650dfccb0f4da9b6ef62ad2d896d0 88 ProSitePatterns PS00831 Ribosomal protein L27 signature. 34 48 - T 06-07-2017 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS28130 26cd9a36713fce5ee3d77134e22c85d0 325 Gene3D G3DSA:3.40.50.2300 63 173 1.5E-9 T 06-07-2017 BWK49_RS28130 26cd9a36713fce5ee3d77134e22c85d0 325 Gene3D G3DSA:1.10.260.40 9 62 3.7E-23 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 BWK49_RS28130 26cd9a36713fce5ee3d77134e22c85d0 325 Pfam PF00356 Bacterial regulatory proteins, lacI family 12 57 3.9E-16 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 BWK49_RS28130 26cd9a36713fce5ee3d77134e22c85d0 325 SMART SM00354 8 80 3.1E-20 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 BWK49_RS28130 26cd9a36713fce5ee3d77134e22c85d0 325 SUPERFAMILY SSF53822 86 324 1.14E-26 T 06-07-2017 IPR028082 Periplasmic binding protein-like I BWK49_RS28130 26cd9a36713fce5ee3d77134e22c85d0 325 Pfam PF13377 Periplasmic binding protein-like domain 168 325 5.3E-30 T 06-07-2017 BWK49_RS28130 26cd9a36713fce5ee3d77134e22c85d0 325 Gene3D G3DSA:3.40.50.2300 174 305 1.5E-24 T 06-07-2017 BWK49_RS28130 26cd9a36713fce5ee3d77134e22c85d0 325 SUPERFAMILY SSF47413 8 68 1.04E-15 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 BWK49_RS27700 817350322f814e9eb5eb1b329881f5d5 590 SUPERFAMILY SSF51011 506 583 1.52E-16 T 06-07-2017 BWK49_RS27700 817350322f814e9eb5eb1b329881f5d5 590 Gene3D G3DSA:3.20.20.80 218 447 2.5E-110 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 BWK49_RS27700 817350322f814e9eb5eb1b329881f5d5 590 Gene3D G3DSA:3.20.20.80 45 142 2.5E-110 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 BWK49_RS27700 817350322f814e9eb5eb1b329881f5d5 590 Gene3D G3DSA:3.20.20.80 480 493 2.5E-110 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 BWK49_RS27700 817350322f814e9eb5eb1b329881f5d5 590 TIGRFAM TIGR02456 treS_nterm: trehalose synthase 43 583 2.9E-285 T 06-07-2017 IPR012810 Trehalose synthase/alpha-amylase, N-terminal GO:0003824|GO:0005975 KEGG: 00500+5.4.99.16|MetaCyc: PWY-2622 BWK49_RS27700 817350322f814e9eb5eb1b329881f5d5 590 SUPERFAMILY SSF51445 54 501 9.61E-131 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily BWK49_RS27700 817350322f814e9eb5eb1b329881f5d5 590 SMART SM00642 51 453 9.9E-117 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 BWK49_RS27700 817350322f814e9eb5eb1b329881f5d5 590 Pfam PF00128 Alpha amylase, catalytic domain 66 422 2.4E-77 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 BWK49_RS27700 817350322f814e9eb5eb1b329881f5d5 590 Gene3D G3DSA:2.60.40.1180 501 582 1.5E-12 T 06-07-2017 IPR013780 Glycosyl hydrolase, all-beta BWK49_RS27700 817350322f814e9eb5eb1b329881f5d5 590 Gene3D G3DSA:3.90.400.10 143 210 7.2E-24 T 06-07-2017 BWK49_RS27700 817350322f814e9eb5eb1b329881f5d5 590 Pfam PF16657 Maltogenic Amylase, C-terminal domain 501 580 4.1E-23 T 06-07-2017 IPR032091 Maltogenic Amylase, C-terminal BWK49_RS15015 30331a8c54952ffdc6a1c0242d5deaa7 84 Gene3D G3DSA:1.10.1200.10 6 82 8.1E-17 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS15015 30331a8c54952ffdc6a1c0242d5deaa7 84 SUPERFAMILY SSF47336 6 82 5.63E-17 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS15015 30331a8c54952ffdc6a1c0242d5deaa7 84 Pfam PF00550 Phosphopantetheine attachment site 11 75 2.2E-13 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS00715 269914e4daa92ac5ea54ddea3789c01f 405 SUPERFAMILY SSF48264 23 399 1.57E-87 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS00715 269914e4daa92ac5ea54ddea3789c01f 405 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 340 349 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 BWK49_RS00715 269914e4daa92ac5ea54ddea3789c01f 405 Gene3D G3DSA:1.10.630.10 22 399 2.1E-112 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS00715 269914e4daa92ac5ea54ddea3789c01f 405 PRINTS PR00359 B-class P450 signature 85 96 3.8E-49 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS00715 269914e4daa92ac5ea54ddea3789c01f 405 PRINTS PR00359 B-class P450 signature 289 316 3.8E-49 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS00715 269914e4daa92ac5ea54ddea3789c01f 405 PRINTS PR00359 B-class P450 signature 191 213 3.8E-49 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS00715 269914e4daa92ac5ea54ddea3789c01f 405 PRINTS PR00359 B-class P450 signature 347 358 3.8E-49 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS00715 269914e4daa92ac5ea54ddea3789c01f 405 PRINTS PR00359 B-class P450 signature 148 163 3.8E-49 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS00715 269914e4daa92ac5ea54ddea3789c01f 405 PRINTS PR00359 B-class P450 signature 338 347 3.8E-49 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS00715 269914e4daa92ac5ea54ddea3789c01f 405 PRINTS PR00359 B-class P450 signature 317 332 3.8E-49 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS00715 269914e4daa92ac5ea54ddea3789c01f 405 PRINTS PR00359 B-class P450 signature 131 147 3.8E-49 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS00715 269914e4daa92ac5ea54ddea3789c01f 405 PRINTS PR00359 B-class P450 signature 272 283 3.8E-49 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS00715 269914e4daa92ac5ea54ddea3789c01f 405 Pfam PF00067 Cytochrome P450 174 368 3.6E-27 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS27160 854ebe348ec1fb2ac64d84f20dd4a2af 705 SUPERFAMILY SSF51445 3 338 1.47E-81 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily BWK49_RS27160 854ebe348ec1fb2ac64d84f20dd4a2af 705 SMART SM01217 620 687 1.4E-20 T 06-07-2017 IPR026891 Fibronectin type III-like domain BWK49_RS27160 854ebe348ec1fb2ac64d84f20dd4a2af 705 PRINTS PR00133 Glycosyl hydrolase family 3 signature 86 105 1.0E-26 T 06-07-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 BWK49_RS27160 854ebe348ec1fb2ac64d84f20dd4a2af 705 PRINTS PR00133 Glycosyl hydrolase family 3 signature 163 179 1.0E-26 T 06-07-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 BWK49_RS27160 854ebe348ec1fb2ac64d84f20dd4a2af 705 PRINTS PR00133 Glycosyl hydrolase family 3 signature 132 148 1.0E-26 T 06-07-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 BWK49_RS27160 854ebe348ec1fb2ac64d84f20dd4a2af 705 PRINTS PR00133 Glycosyl hydrolase family 3 signature 233 251 1.0E-26 T 06-07-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 BWK49_RS27160 854ebe348ec1fb2ac64d84f20dd4a2af 705 PRINTS PR00133 Glycosyl hydrolase family 3 signature 57 73 1.0E-26 T 06-07-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 BWK49_RS27160 854ebe348ec1fb2ac64d84f20dd4a2af 705 Gene3D G3DSA:3.20.20.300 3 318 2.3E-87 T 06-07-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 BWK49_RS27160 854ebe348ec1fb2ac64d84f20dd4a2af 705 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 58 306 7.1E-44 T 06-07-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 BWK49_RS27160 854ebe348ec1fb2ac64d84f20dd4a2af 705 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 340 588 6.2E-51 T 06-07-2017 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 BWK49_RS27160 854ebe348ec1fb2ac64d84f20dd4a2af 705 Pfam PF14310 Fibronectin type III-like domain 620 686 2.3E-15 T 06-07-2017 IPR026891 Fibronectin type III-like domain BWK49_RS27160 854ebe348ec1fb2ac64d84f20dd4a2af 705 SUPERFAMILY SSF52279 407 541 3.14E-47 T 06-07-2017 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 BWK49_RS27160 854ebe348ec1fb2ac64d84f20dd4a2af 705 SUPERFAMILY SSF52279 569 591 3.14E-47 T 06-07-2017 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 BWK49_RS27160 854ebe348ec1fb2ac64d84f20dd4a2af 705 SUPERFAMILY SSF52279 340 366 3.14E-47 T 06-07-2017 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 BWK49_RS27160 854ebe348ec1fb2ac64d84f20dd4a2af 705 Gene3D G3DSA:3.40.50.1700 326 591 8.9E-64 T 06-07-2017 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 BWK49_RS24405 0dd97c7c72abae7cbb1264fe9d8bf615 272 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 157 185 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS24405 0dd97c7c72abae7cbb1264fe9d8bf615 272 SUPERFAMILY SSF51735 4 271 8.92E-72 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS24405 0dd97c7c72abae7cbb1264fe9d8bf615 272 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 170 189 1.8E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS24405 0dd97c7c72abae7cbb1264fe9d8bf615 272 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 158 1.8E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS24405 0dd97c7c72abae7cbb1264fe9d8bf615 272 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 96 107 1.8E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS24405 0dd97c7c72abae7cbb1264fe9d8bf615 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 4.0E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS24405 0dd97c7c72abae7cbb1264fe9d8bf615 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 189 4.0E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS24405 0dd97c7c72abae7cbb1264fe9d8bf615 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 191 208 4.0E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS24405 0dd97c7c72abae7cbb1264fe9d8bf615 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 96 107 4.0E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS24405 0dd97c7c72abae7cbb1264fe9d8bf615 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 160 4.0E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS24405 0dd97c7c72abae7cbb1264fe9d8bf615 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 233 253 4.0E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS24405 0dd97c7c72abae7cbb1264fe9d8bf615 272 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 211 0.0028 T 06-07-2017 BWK49_RS24405 0dd97c7c72abae7cbb1264fe9d8bf615 272 Gene3D G3DSA:3.40.50.720 3 269 2.6E-77 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS24405 0dd97c7c72abae7cbb1264fe9d8bf615 272 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 268 2.7E-50 T 06-07-2017 BWK49_RS24405 0dd97c7c72abae7cbb1264fe9d8bf615 272 TIGRFAM TIGR03971 SDR_subfam_1: SDR family mycofactocin-dependent oxidoreductase 5 270 3.4E-111 T 06-07-2017 IPR023985 Mycofactocin-dependent oxidoreductase BWK49_RS09845 6a18eb4e419f1640a3b0f3c94a6aaa9b 534 Gene3D G3DSA:3.20.20.80 197 470 2.5E-108 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 BWK49_RS09845 6a18eb4e419f1640a3b0f3c94a6aaa9b 534 Gene3D G3DSA:3.20.20.80 16 118 2.5E-108 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 BWK49_RS09845 6a18eb4e419f1640a3b0f3c94a6aaa9b 534 SMART SM00642 27 412 1.0E-122 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 BWK49_RS09845 6a18eb4e419f1640a3b0f3c94a6aaa9b 534 SUPERFAMILY SSF51445 18 468 1.6E-122 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily BWK49_RS09845 6a18eb4e419f1640a3b0f3c94a6aaa9b 534 Gene3D G3DSA:3.90.400.10 119 196 3.0E-29 T 06-07-2017 BWK49_RS09845 6a18eb4e419f1640a3b0f3c94a6aaa9b 534 Pfam PF00128 Alpha amylase, catalytic domain 42 387 8.0E-81 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 BWK49_RS09845 6a18eb4e419f1640a3b0f3c94a6aaa9b 534 Pfam PF11941 Domain of unknown function (DUF3459) 458 533 1.2E-5 T 06-07-2017 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) BWK49_RS00720 3100505cf2ad80e5cca06a86f34a3aef 557 SUPERFAMILY SSF53300 359 535 4.25E-19 T 06-07-2017 IPR002035 von Willebrand factor, type A BWK49_RS00720 3100505cf2ad80e5cca06a86f34a3aef 557 Pfam PF13519 von Willebrand factor type A domain 360 474 2.6E-8 T 06-07-2017 IPR002035 von Willebrand factor, type A BWK49_RS00720 3100505cf2ad80e5cca06a86f34a3aef 557 SMART SM00327 357 548 4.6E-15 T 06-07-2017 IPR002035 von Willebrand factor, type A BWK49_RS00720 3100505cf2ad80e5cca06a86f34a3aef 557 Gene3D G3DSA:3.40.50.410 360 534 2.1E-10 T 06-07-2017 IPR002035 von Willebrand factor, type A BWK49_RS11345 5d6ec31730f0fd74d5d2d44ff87219f7 205 SUPERFAMILY SSF48498 94 201 1.16E-8 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS11345 5d6ec31730f0fd74d5d2d44ff87219f7 205 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 66 2.2E-14 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS11345 5d6ec31730f0fd74d5d2d44ff87219f7 205 SUPERFAMILY SSF46689 7 85 3.69E-19 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS11345 5d6ec31730f0fd74d5d2d44ff87219f7 205 Gene3D G3DSA:1.10.357.10 68 201 1.3E-12 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS11345 5d6ec31730f0fd74d5d2d44ff87219f7 205 ProSitePatterns PS01081 TetR-type HTH domain signature. 32 62 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site BWK49_RS11345 5d6ec31730f0fd74d5d2d44ff87219f7 205 Gene3D G3DSA:1.10.10.60 6 49 1.7E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS11345 5d6ec31730f0fd74d5d2d44ff87219f7 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 5.4E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS11345 5d6ec31730f0fd74d5d2d44ff87219f7 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 5.4E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS11345 5d6ec31730f0fd74d5d2d44ff87219f7 205 Gene3D G3DSA:1.10.10.60 50 67 7.9E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS02515 3d8e6bcde5bd4d667facb047f7abcd4a 330 SUPERFAMILY SSF53098 17 287 1.9E-40 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS02515 3d8e6bcde5bd4d667facb047f7abcd4a 330 Gene3D G3DSA:3.30.420.10 16 178 9.1E-41 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS02515 3d8e6bcde5bd4d667facb047f7abcd4a 330 Gene3D G3DSA:3.40.50.10190 231 306 2.4E-8 T 06-07-2017 IPR001357 BRCT domain BWK49_RS02515 3d8e6bcde5bd4d667facb047f7abcd4a 330 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 18 175 1.0E-22 T 06-07-2017 IPR006054 DNA polymerase III, epsilon subunit GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 BWK49_RS02515 3d8e6bcde5bd4d667facb047f7abcd4a 330 SMART SM00479 16 181 1.7E-35 T 06-07-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III BWK49_RS02515 3d8e6bcde5bd4d667facb047f7abcd4a 330 Pfam PF00929 Exonuclease 19 169 4.0E-20 T 06-07-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III BWK49_RS09145 0197a33cffd1434d262f1f4123ce7c2d 116 TIGRFAM TIGR03954 integ_memb_HG: integral membrane protein 26 104 1.2E-18 T 06-07-2017 IPR023845 Domain of unknown function DUF3817, transmembrane BWK49_RS09145 0197a33cffd1434d262f1f4123ce7c2d 116 Pfam PF12823 Domain of unknown function (DUF3817) 26 107 2.8E-21 T 06-07-2017 IPR023845 Domain of unknown function DUF3817, transmembrane BWK49_RS14005 d8acf647132d635851569547b958b611 342 SUPERFAMILY SSF47413 9 76 1.27E-14 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 BWK49_RS14005 d8acf647132d635851569547b958b611 342 SMART SM00530 10 65 2.1E-13 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 BWK49_RS14005 d8acf647132d635851569547b958b611 342 Gene3D G3DSA:1.10.260.40 9 67 4.5E-14 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 BWK49_RS14005 d8acf647132d635851569547b958b611 342 Pfam PF01381 Helix-turn-helix 11 63 2.3E-11 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 BWK49_RS14005 d8acf647132d635851569547b958b611 342 Pfam PF06114 Domain of unknown function (DUF955) 157 271 3.0E-19 T 06-07-2017 IPR010359 HTH domain, IrrE-type BWK49_RS09915 192794e16cd1b76ba2efdfa432f07d88 196 SUPERFAMILY SSF52096 13 186 5.27E-63 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS09915 192794e16cd1b76ba2efdfa432f07d88 196 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 1 187 37.842 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 BWK49_RS09915 192794e16cd1b76ba2efdfa432f07d88 196 Gene3D G3DSA:3.90.226.10 13 187 5.3E-72 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS09915 192794e16cd1b76ba2efdfa432f07d88 196 Pfam PF00574 Clp protease 11 186 1.2E-74 T 06-07-2017 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA BWK49_RS09915 192794e16cd1b76ba2efdfa432f07d88 196 PRINTS PR00127 Clp protease catalytic subunit P signature 13 28 1.3E-47 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 BWK49_RS09915 192794e16cd1b76ba2efdfa432f07d88 196 PRINTS PR00127 Clp protease catalytic subunit P signature 53 73 1.3E-47 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 BWK49_RS09915 192794e16cd1b76ba2efdfa432f07d88 196 PRINTS PR00127 Clp protease catalytic subunit P signature 162 181 1.3E-47 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 BWK49_RS09915 192794e16cd1b76ba2efdfa432f07d88 196 PRINTS PR00127 Clp protease catalytic subunit P signature 105 124 1.3E-47 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 BWK49_RS09915 192794e16cd1b76ba2efdfa432f07d88 196 PRINTS PR00127 Clp protease catalytic subunit P signature 84 101 1.3E-47 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 BWK49_RS09915 192794e16cd1b76ba2efdfa432f07d88 196 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 106 119 - T 06-07-2017 IPR033135 ClpP, histidine active site BWK49_RS23165 76b24776030b9b518b837ee0543cbc32 549 Pfam PF13193 AMP-binding enzyme C-terminal domain 421 497 2.5E-7 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS23165 76b24776030b9b518b837ee0543cbc32 549 Pfam PF00501 AMP-binding enzyme 23 411 1.1E-58 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS23165 76b24776030b9b518b837ee0543cbc32 549 Gene3D G3DSA:2.30.38.10 339 404 8.1E-17 T 06-07-2017 BWK49_RS23165 76b24776030b9b518b837ee0543cbc32 549 ProSitePatterns PS00455 Putative AMP-binding domain signature. 157 168 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS23165 76b24776030b9b518b837ee0543cbc32 549 Gene3D G3DSA:3.40.50.980 161 320 8.6E-21 T 06-07-2017 BWK49_RS23165 76b24776030b9b518b837ee0543cbc32 549 Gene3D G3DSA:3.40.50.980 21 160 4.4E-18 T 06-07-2017 BWK49_RS23165 76b24776030b9b518b837ee0543cbc32 549 Gene3D G3DSA:3.30.300.30 407 506 2.4E-15 T 06-07-2017 BWK49_RS23165 76b24776030b9b518b837ee0543cbc32 549 SUPERFAMILY SSF56801 16 511 2.62E-95 T 06-07-2017 BWK49_RS17275 3c2a309615675f718794fa71d33d21ff 272 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 5 260 34.53 T 06-07-2017 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 BWK49_RS17275 3c2a309615675f718794fa71d33d21ff 272 Hamap MF_00134_A Indole-3-glycerol phosphate synthase [trpC]. 24 256 29.276 T 06-07-2017 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 BWK49_RS17275 3c2a309615675f718794fa71d33d21ff 272 Pfam PF00218 Indole-3-glycerol phosphate synthase 7 258 2.6E-80 T 06-07-2017 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 BWK49_RS17275 3c2a309615675f718794fa71d33d21ff 272 Gene3D G3DSA:3.20.20.70 5 262 2.5E-95 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 BWK49_RS17275 3c2a309615675f718794fa71d33d21ff 272 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 54 71 - T 06-07-2017 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 BWK49_RS17275 3c2a309615675f718794fa71d33d21ff 272 SUPERFAMILY SSF51366 15 260 1.73E-79 T 06-07-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 BWK49_RS04665 32570c6321466ef53afa79c40c3f5e7a 111 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 9 80 1.1E-26 T 06-07-2017 IPR025161 Putative transposase IS4/IS5 family BWK49_RS09585 5e5075507f6a81fd599131d58c2d369b 381 Pfam PF00355 Rieske [2Fe-2S] domain 54 134 2.8E-18 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS09585 5e5075507f6a81fd599131d58c2d369b 381 SUPERFAMILY SSF50022 21 164 2.88E-39 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS09585 5e5075507f6a81fd599131d58c2d369b 381 SUPERFAMILY SSF55961 169 378 1.57E-31 T 06-07-2017 BWK49_RS09585 5e5075507f6a81fd599131d58c2d369b 381 Gene3D G3DSA:2.102.10.10 54 155 1.1E-32 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS09585 5e5075507f6a81fd599131d58c2d369b 381 Gene3D G3DSA:3.90.380.10 156 228 5.0E-10 T 06-07-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 BWK49_RS09585 5e5075507f6a81fd599131d58c2d369b 381 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 188 376 2.1E-27 T 06-07-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 BWK49_RS21160 7dd48812b87445937798ff3ff9fda3d7 510 Pfam PF01593 Flavin containing amine oxidoreductase 37 476 5.7E-29 T 06-07-2017 IPR002937 Amine oxidase GO:0016491|GO:0055114 BWK49_RS21160 7dd48812b87445937798ff3ff9fda3d7 510 PRINTS PR00419 Adrenodoxin reductase family signature 29 51 4.9E-6 T 06-07-2017 BWK49_RS21160 7dd48812b87445937798ff3ff9fda3d7 510 PRINTS PR00419 Adrenodoxin reductase family signature 52 65 4.9E-6 T 06-07-2017 BWK49_RS21160 7dd48812b87445937798ff3ff9fda3d7 510 SUPERFAMILY SSF51905 26 345 3.33E-45 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS21160 7dd48812b87445937798ff3ff9fda3d7 510 SUPERFAMILY SSF51905 435 479 3.33E-45 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS21160 7dd48812b87445937798ff3ff9fda3d7 510 Gene3D G3DSA:3.50.50.60 216 322 1.4E-31 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS21160 7dd48812b87445937798ff3ff9fda3d7 510 Gene3D G3DSA:3.50.50.60 422 477 1.4E-31 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS21160 7dd48812b87445937798ff3ff9fda3d7 510 Gene3D G3DSA:3.50.50.60 27 108 1.4E-31 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS22210 974cf9e317638e674a5e91b498faae19 98 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 1 90 8.6E-23 T 06-07-2017 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:0015992 BWK49_RS22210 974cf9e317638e674a5e91b498faae19 98 Pfam PF03334 Na+/H+ antiporter subunit 1 76 1.1E-20 T 06-07-2017 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:0015992 BWK49_RS27590 e8c936c2c162e349cda1c46826085ed8 224 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 56 79 2.3E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS27590 e8c936c2c162e349cda1c46826085ed8 224 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 48 2.3E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS27590 e8c936c2c162e349cda1c46826085ed8 224 Pfam PF00440 Bacterial regulatory proteins, tetR family 35 77 2.2E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS27590 e8c936c2c162e349cda1c46826085ed8 224 Gene3D G3DSA:1.10.357.10 23 217 2.5E-33 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS27590 e8c936c2c162e349cda1c46826085ed8 224 SUPERFAMILY SSF46689 24 96 3.59E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS06510 5eb60d5211745f8d3c1e3806781a5280 286 Gene3D G3DSA:3.20.20.30 125 281 5.1E-14 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS06510 5eb60d5211745f8d3c1e3806781a5280 286 Gene3D G3DSA:3.20.20.30 16 124 7.5E-15 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS06510 5eb60d5211745f8d3c1e3806781a5280 286 TIGRFAM TIGR03620 F420_MSMEG_4141: probable F420-dependent oxidoreductase, MSMEG_4141 family 4 284 1.1E-116 T 06-07-2017 IPR019922 Luciferase-like, F420-dependent oxidoreductase, MSMEG4141, predicted BWK49_RS06510 5eb60d5211745f8d3c1e3806781a5280 286 SUPERFAMILY SSF51679 11 279 1.62E-39 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS06510 5eb60d5211745f8d3c1e3806781a5280 286 Pfam PF00296 Luciferase-like monooxygenase 14 123 1.3E-13 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS06510 5eb60d5211745f8d3c1e3806781a5280 286 Pfam PF00296 Luciferase-like monooxygenase 122 260 1.4E-6 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS24280 9c52962a1f0a358a1180ebce77afa18f 115 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 35 113 24.26 T 06-07-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS24280 9c52962a1f0a358a1180ebce77afa18f 115 Pfam PF00366 Ribosomal protein S17 42 109 2.8E-29 T 06-07-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS24280 9c52962a1f0a358a1180ebce77afa18f 115 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 37 108 6.0E-34 T 06-07-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS24280 9c52962a1f0a358a1180ebce77afa18f 115 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 37 108 1.8E-32 T 06-07-2017 IPR019984 Ribosomal protein S17, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS24280 9c52962a1f0a358a1180ebce77afa18f 115 Gene3D G3DSA:2.40.50.140 36 114 9.8E-34 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS24280 9c52962a1f0a358a1180ebce77afa18f 115 SUPERFAMILY SSF50249 36 114 7.28E-30 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS24280 9c52962a1f0a358a1180ebce77afa18f 115 PRINTS PR00973 Ribosomal protein S17 family signature 98 105 1.8E-11 T 06-07-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS24280 9c52962a1f0a358a1180ebce77afa18f 115 PRINTS PR00973 Ribosomal protein S17 family signature 56 79 1.8E-11 T 06-07-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS24280 9c52962a1f0a358a1180ebce77afa18f 115 PRINTS PR00973 Ribosomal protein S17 family signature 88 98 1.8E-11 T 06-07-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS25045 e6578b69cd580c53060c61be83915db7 300 TIGRFAM TIGR01929 menB: naphthoate synthase 20 296 5.9E-137 T 06-07-2017 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 BWK49_RS25045 e6578b69cd580c53060c61be83915db7 300 Gene3D G3DSA:3.90.226.10 21 236 5.6E-67 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS25045 e6578b69cd580c53060c61be83915db7 300 SUPERFAMILY SSF52096 22 296 4.81E-76 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS25045 e6578b69cd580c53060c61be83915db7 300 Gene3D G3DSA:1.10.12.10 239 288 3.1E-28 T 06-07-2017 IPR014748 Crontonase, C-terminal BWK49_RS25045 e6578b69cd580c53060c61be83915db7 300 Hamap MF_01934 1,4-dihydroxy-2-naphthoyl-CoA synthase [menB]. 11 299 52.89 T 06-07-2017 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 BWK49_RS25045 e6578b69cd580c53060c61be83915db7 300 Pfam PF00378 Enoyl-CoA hydratase/isomerase 34 294 7.7E-52 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 BWK49_RS06010 7a1828f6f524c7ea5160b27daf0378a3 379 Pfam PF00557 Metallopeptidase family M24 159 364 1.0E-18 T 06-07-2017 IPR000994 Peptidase M24, structural domain BWK49_RS06010 7a1828f6f524c7ea5160b27daf0378a3 379 SUPERFAMILY SSF53092 6 148 1.26E-16 T 06-07-2017 IPR028980 Creatinase/Aminopeptidase P, N-terminal BWK49_RS06010 7a1828f6f524c7ea5160b27daf0378a3 379 Gene3D G3DSA:3.90.230.10 150 375 1.4E-25 T 06-07-2017 IPR000994 Peptidase M24, structural domain BWK49_RS06010 7a1828f6f524c7ea5160b27daf0378a3 379 Pfam PF01321 Creatinase/Prolidase N-terminal domain 16 150 2.1E-10 T 06-07-2017 IPR000587 Creatinase, N-terminal GO:0016787 BWK49_RS06010 7a1828f6f524c7ea5160b27daf0378a3 379 SUPERFAMILY SSF55920 150 376 5.23E-32 T 06-07-2017 IPR000994 Peptidase M24, structural domain BWK49_RS06010 7a1828f6f524c7ea5160b27daf0378a3 379 Gene3D G3DSA:3.40.350.10 15 148 8.6E-15 T 06-07-2017 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal BWK49_RS11065 c17f84f532ae1952a9b6d2eaa36d2422 416 SUPERFAMILY SSF54637 29 174 1.27E-7 T 06-07-2017 IPR029069 HotDog domain BWK49_RS11065 c17f84f532ae1952a9b6d2eaa36d2422 416 SUPERFAMILY SSF54637 279 387 9.8E-13 T 06-07-2017 IPR029069 HotDog domain BWK49_RS11065 c17f84f532ae1952a9b6d2eaa36d2422 416 Gene3D G3DSA:3.10.129.10 280 386 4.8E-21 T 06-07-2017 IPR029069 HotDog domain BWK49_RS11065 c17f84f532ae1952a9b6d2eaa36d2422 416 Gene3D G3DSA:3.10.129.10 33 171 4.4E-5 T 06-07-2017 IPR029069 HotDog domain BWK49_RS11065 c17f84f532ae1952a9b6d2eaa36d2422 416 Gene3D G3DSA:3.10.129.10 207 247 4.8E-21 T 06-07-2017 IPR029069 HotDog domain BWK49_RS08245 342695681efc879d867ebc23e8aefd1b 130 Gene3D G3DSA:3.90.79.10 4 126 1.3E-28 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 BWK49_RS08245 342695681efc879d867ebc23e8aefd1b 130 Pfam PF00293 NUDIX domain 6 125 1.6E-16 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 BWK49_RS08245 342695681efc879d867ebc23e8aefd1b 130 ProSitePatterns PS00893 Nudix box signature. 37 58 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 BWK49_RS08245 342695681efc879d867ebc23e8aefd1b 130 SUPERFAMILY SSF55811 1 126 1.0E-27 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 BWK49_RS08245 342695681efc879d867ebc23e8aefd1b 130 PRINTS PR00502 NUDIX hydrolase family signature 32 46 3.9E-7 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 BWK49_RS08245 342695681efc879d867ebc23e8aefd1b 130 PRINTS PR00502 NUDIX hydrolase family signature 46 61 3.9E-7 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 BWK49_RS11385 2a7d5eb9c37e2b58e3bc53fd050162c4 1479 SUPERFAMILY SSF52777 1049 1241 8.89E-25 T 06-07-2017 BWK49_RS11385 2a7d5eb9c37e2b58e3bc53fd050162c4 1479 SUPERFAMILY SSF52777 11 209 1.78E-40 T 06-07-2017 BWK49_RS11385 2a7d5eb9c37e2b58e3bc53fd050162c4 1479 SMART SM01294 973 1036 0.0025 T 06-07-2017 BWK49_RS11385 2a7d5eb9c37e2b58e3bc53fd050162c4 1479 Gene3D G3DSA:3.40.50.980 470 610 1.9E-40 T 06-07-2017 BWK49_RS11385 2a7d5eb9c37e2b58e3bc53fd050162c4 1479 SMART SM00823 Phosphopantetheine attachment site 972 1040 1.4E-5 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS11385 2a7d5eb9c37e2b58e3bc53fd050162c4 1479 SUPERFAMILY SSF52777 1232 1478 7.78E-15 T 06-07-2017 BWK49_RS11385 2a7d5eb9c37e2b58e3bc53fd050162c4 1479 Pfam PF00550 Phosphopantetheine attachment site 974 1036 2.0E-9 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS11385 2a7d5eb9c37e2b58e3bc53fd050162c4 1479 SUPERFAMILY SSF47336 966 1037 1.44E-13 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS11385 2a7d5eb9c37e2b58e3bc53fd050162c4 1479 Pfam PF00501 AMP-binding enzyme 476 862 1.8E-79 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS11385 2a7d5eb9c37e2b58e3bc53fd050162c4 1479 Gene3D G3DSA:2.30.38.10 776 851 5.4E-25 T 06-07-2017 BWK49_RS11385 2a7d5eb9c37e2b58e3bc53fd050162c4 1479 Gene3D G3DSA:3.30.300.30 858 976 2.2E-34 T 06-07-2017 BWK49_RS11385 2a7d5eb9c37e2b58e3bc53fd050162c4 1479 Pfam PF13193 AMP-binding enzyme C-terminal domain 870 946 2.5E-11 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS11385 2a7d5eb9c37e2b58e3bc53fd050162c4 1479 Gene3D G3DSA:3.40.50.980 611 775 6.4E-27 T 06-07-2017 BWK49_RS11385 2a7d5eb9c37e2b58e3bc53fd050162c4 1479 SUPERFAMILY SSF52777 196 442 1.22E-44 T 06-07-2017 BWK49_RS11385 2a7d5eb9c37e2b58e3bc53fd050162c4 1479 Gene3D G3DSA:1.10.1200.10 977 1041 1.9E-17 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS11385 2a7d5eb9c37e2b58e3bc53fd050162c4 1479 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 497 885 5.6E-107 T 06-07-2017 IPR010071 Amino acid adenylation domain BWK49_RS11385 2a7d5eb9c37e2b58e3bc53fd050162c4 1479 SUPERFAMILY SSF56801 465 984 1.03E-128 T 06-07-2017 BWK49_RS11385 2a7d5eb9c37e2b58e3bc53fd050162c4 1479 Pfam PF00668 Condensation domain 1074 1350 7.9E-16 T 06-07-2017 IPR001242 Condensation domain BWK49_RS11385 2a7d5eb9c37e2b58e3bc53fd050162c4 1479 Pfam PF00668 Condensation domain 13 314 1.6E-52 T 06-07-2017 IPR001242 Condensation domain BWK49_RS11385 2a7d5eb9c37e2b58e3bc53fd050162c4 1479 ProSitePatterns PS00455 Putative AMP-binding domain signature. 603 614 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS24390 f38364069c4af66cdceef0f0bca9d672 274 Pfam PF00248 Aldo/keto reductase family 22 258 1.1E-45 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain BWK49_RS24390 f38364069c4af66cdceef0f0bca9d672 274 PIRSF PIRSF000097 2 272 1.9E-74 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 BWK49_RS24390 f38364069c4af66cdceef0f0bca9d672 274 Gene3D G3DSA:3.20.20.100 3 270 5.1E-94 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain BWK49_RS24390 f38364069c4af66cdceef0f0bca9d672 274 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 123 140 - T 06-07-2017 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 BWK49_RS24390 f38364069c4af66cdceef0f0bca9d672 274 PRINTS PR00069 Aldo-keto reductase signature 91 109 4.3E-46 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 BWK49_RS24390 f38364069c4af66cdceef0f0bca9d672 274 PRINTS PR00069 Aldo-keto reductase signature 194 218 4.3E-46 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 BWK49_RS24390 f38364069c4af66cdceef0f0bca9d672 274 PRINTS PR00069 Aldo-keto reductase signature 35 59 4.3E-46 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 BWK49_RS24390 f38364069c4af66cdceef0f0bca9d672 274 PRINTS PR00069 Aldo-keto reductase signature 157 186 4.3E-46 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 BWK49_RS24390 f38364069c4af66cdceef0f0bca9d672 274 PRINTS PR00069 Aldo-keto reductase signature 123 140 4.3E-46 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 BWK49_RS24390 f38364069c4af66cdceef0f0bca9d672 274 SUPERFAMILY SSF51430 3 269 1.07E-85 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain BWK49_RS14540 a82f276f5ba3316279edb915594229ea 614 Gene3D G3DSA:3.30.300.30 494 605 2.3E-15 T 06-07-2017 BWK49_RS14540 a82f276f5ba3316279edb915594229ea 614 Gene3D G3DSA:3.40.50.980 34 203 2.2E-22 T 06-07-2017 BWK49_RS14540 a82f276f5ba3316279edb915594229ea 614 Gene3D G3DSA:2.30.38.10 401 492 3.8E-17 T 06-07-2017 BWK49_RS14540 a82f276f5ba3316279edb915594229ea 614 Gene3D G3DSA:3.40.50.980 204 371 3.6E-19 T 06-07-2017 BWK49_RS14540 a82f276f5ba3316279edb915594229ea 614 Pfam PF00501 AMP-binding enzyme 41 502 4.9E-58 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS14540 a82f276f5ba3316279edb915594229ea 614 SUPERFAMILY SSF56801 34 608 5.63E-84 T 06-07-2017 BWK49_RS03795 a3e93f78002897cc7b71af68c801fa4f 275 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 146 174 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS03795 a3e93f78002897cc7b71af68c801fa4f 275 Gene3D G3DSA:3.40.50.720 11 240 2.4E-57 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS03795 a3e93f78002897cc7b71af68c801fa4f 275 Pfam PF00106 short chain dehydrogenase 13 200 1.4E-45 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS03795 a3e93f78002897cc7b71af68c801fa4f 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 2.5E-18 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS03795 a3e93f78002897cc7b71af68c801fa4f 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 2.5E-18 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS03795 a3e93f78002897cc7b71af68c801fa4f 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 2.5E-18 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS03795 a3e93f78002897cc7b71af68c801fa4f 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 2.5E-18 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS03795 a3e93f78002897cc7b71af68c801fa4f 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 2.5E-18 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS03795 a3e93f78002897cc7b71af68c801fa4f 275 SUPERFAMILY SSF51735 11 241 5.71E-56 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS15115 22ac218a4a3a6c0b81bf7cafda4d11f6 209 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 55 77 - T 06-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 BWK49_RS15115 22ac218a4a3a6c0b81bf7cafda4d11f6 209 Pfam PF01066 CDP-alcohol phosphatidyltransferase 13 77 7.7E-13 T 06-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 BWK49_RS15115 22ac218a4a3a6c0b81bf7cafda4d11f6 209 PIRSF PIRSF000847 8 195 2.2E-42 T 06-07-2017 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668 BWK49_RS05385 b3255b710ff653f98645f4089c944db9 204 SUPERFAMILY SSF56349 17 195 2.68E-29 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 BWK49_RS05385 b3255b710ff653f98645f4089c944db9 204 Pfam PF00589 Phage integrase family 16 187 2.9E-21 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 BWK49_RS05385 b3255b710ff653f98645f4089c944db9 204 Gene3D G3DSA:1.10.443.10 18 194 2.0E-28 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 BWK49_RS28660 29e9e93821e57bfddd7f40d4890d8b10 188 SUPERFAMILY SSF46689 144 185 7.7E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS28660 29e9e93821e57bfddd7f40d4890d8b10 188 SUPERFAMILY SSF53041 4 138 9.94E-35 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 BWK49_RS28660 29e9e93821e57bfddd7f40d4890d8b10 188 Pfam PF02796 Helix-turn-helix domain of resolvase 145 186 1.5E-8 T 06-07-2017 IPR006120 Resolvase, HTH domain GO:0000150|GO:0003677|GO:0006310 BWK49_RS28660 29e9e93821e57bfddd7f40d4890d8b10 188 ProSitePatterns PS00397 Site-specific recombinases active site. 7 15 - T 06-07-2017 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 BWK49_RS28660 29e9e93821e57bfddd7f40d4890d8b10 188 Gene3D G3DSA:3.40.50.1390 4 123 3.7E-36 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 BWK49_RS28660 29e9e93821e57bfddd7f40d4890d8b10 188 ProSitePatterns PS00398 Site-specific recombinases signature 2. 60 72 - T 06-07-2017 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 BWK49_RS28660 29e9e93821e57bfddd7f40d4890d8b10 188 Gene3D G3DSA:1.10.10.60 144 185 3.9E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS28660 29e9e93821e57bfddd7f40d4890d8b10 188 Pfam PF00239 Resolvase, N terminal domain 5 137 9.2E-33 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 BWK49_RS28660 29e9e93821e57bfddd7f40d4890d8b10 188 SMART SM00857 4 141 1.5E-40 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 BWK49_RS11435 16524dcac2ac499a2ecb7e24b6f1c24f 253 SUPERFAMILY SSF75217 76 248 1.52E-41 T 06-07-2017 IPR029028 Alpha/beta knot methyltransferases BWK49_RS11435 16524dcac2ac499a2ecb7e24b6f1c24f 253 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 13 243 1.4E-32 T 06-07-2017 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 BWK49_RS11435 16524dcac2ac499a2ecb7e24b6f1c24f 253 PIRSF PIRSF015601 2 247 3.1E-43 T 06-07-2017 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 BWK49_RS11435 16524dcac2ac499a2ecb7e24b6f1c24f 253 SUPERFAMILY SSF88697 5 70 7.7E-12 T 06-07-2017 IPR015947 PUA-like domain BWK49_RS11435 16524dcac2ac499a2ecb7e24b6f1c24f 253 Gene3D G3DSA:3.40.1280.10 5 248 1.8E-64 T 06-07-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal BWK49_RS11435 16524dcac2ac499a2ecb7e24b6f1c24f 253 Pfam PF04452 RNA methyltransferase 20 240 1.0E-58 T 06-07-2017 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 BWK49_RS13340 11d196448e0981489af7aacc42402c5f 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 3.3E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS13340 11d196448e0981489af7aacc42402c5f 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 3.3E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS13340 11d196448e0981489af7aacc42402c5f 200 SUPERFAMILY SSF46689 10 89 6.48E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS13340 11d196448e0981489af7aacc42402c5f 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 64 4.0E-13 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS13340 11d196448e0981489af7aacc42402c5f 200 Gene3D G3DSA:1.10.357.10 63 194 3.1E-13 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS13340 11d196448e0981489af7aacc42402c5f 200 Gene3D G3DSA:1.10.10.60 10 62 1.7E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS00390 9efd15caa2d46337a42318e6b2162193 152 SUPERFAMILY SSF55658 1 57 5.06E-17 T 06-07-2017 IPR009027 Ribosomal protein L9/RNase H1, N-terminal BWK49_RS00390 9efd15caa2d46337a42318e6b2162193 152 Pfam PF03948 Ribosomal protein L9, C-terminal domain 64 150 2.8E-23 T 06-07-2017 IPR020069 Ribosomal protein L9, C-terminal BWK49_RS00390 9efd15caa2d46337a42318e6b2162193 152 SUPERFAMILY SSF55653 62 150 7.06E-21 T 06-07-2017 IPR020069 Ribosomal protein L9, C-terminal BWK49_RS00390 9efd15caa2d46337a42318e6b2162193 152 Gene3D G3DSA:3.40.5.10 1 50 3.6E-21 T 06-07-2017 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS00390 9efd15caa2d46337a42318e6b2162193 152 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 06-07-2017 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS00390 9efd15caa2d46337a42318e6b2162193 152 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 151 24.302 T 06-07-2017 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS00390 9efd15caa2d46337a42318e6b2162193 152 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 150 1.3E-34 T 06-07-2017 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS00390 9efd15caa2d46337a42318e6b2162193 152 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 46 7.3E-20 T 06-07-2017 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS00390 9efd15caa2d46337a42318e6b2162193 152 Gene3D G3DSA:3.10.430.100 62 151 5.6E-25 T 06-07-2017 IPR020069 Ribosomal protein L9, C-terminal BWK49_RS19690 3864e2345a2e19f7a5b17134e65a7c11 266 Hamap MF_00008 Thymidylate synthase [thyA]. 4 266 38.946 T 06-07-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 BWK49_RS19690 3864e2345a2e19f7a5b17134e65a7c11 266 Pfam PF00303 Thymidylate synthase 6 266 5.8E-117 T 06-07-2017 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 BWK49_RS19690 3864e2345a2e19f7a5b17134e65a7c11 266 ProSitePatterns PS00091 Thymidylate synthase active site. 129 157 - T 06-07-2017 IPR020940 Thymidylate synthase, active site GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 BWK49_RS19690 3864e2345a2e19f7a5b17134e65a7c11 266 PRINTS PR00108 Thymidylate synthase family signature 118 137 1.7E-48 T 06-07-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 BWK49_RS19690 3864e2345a2e19f7a5b17134e65a7c11 266 PRINTS PR00108 Thymidylate synthase family signature 144 159 1.7E-48 T 06-07-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 BWK49_RS19690 3864e2345a2e19f7a5b17134e65a7c11 266 PRINTS PR00108 Thymidylate synthase family signature 200 217 1.7E-48 T 06-07-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 BWK49_RS19690 3864e2345a2e19f7a5b17134e65a7c11 266 PRINTS PR00108 Thymidylate synthase family signature 45 66 1.7E-48 T 06-07-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 BWK49_RS19690 3864e2345a2e19f7a5b17134e65a7c11 266 PRINTS PR00108 Thymidylate synthase family signature 162 188 1.7E-48 T 06-07-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 BWK49_RS19690 3864e2345a2e19f7a5b17134e65a7c11 266 Gene3D G3DSA:3.30.572.10 7 266 2.0E-125 T 06-07-2017 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 BWK49_RS19690 3864e2345a2e19f7a5b17134e65a7c11 266 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 88 266 3.4E-90 T 06-07-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 BWK49_RS19690 3864e2345a2e19f7a5b17134e65a7c11 266 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 6 88 1.9E-37 T 06-07-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 BWK49_RS19690 3864e2345a2e19f7a5b17134e65a7c11 266 SUPERFAMILY SSF55831 6 266 4.58E-123 T 06-07-2017 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 BWK49_RS25200 381c8b9546f0b6537e09cc87fcbd0ef1 450 ProSitePatterns PS00217 Sugar transport proteins signature 2. 145 170 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 BWK49_RS25200 381c8b9546f0b6537e09cc87fcbd0ef1 450 SUPERFAMILY SSF103473 27 445 3.01E-59 T 06-07-2017 IPR020846 Major facilitator superfamily domain BWK49_RS25200 381c8b9546f0b6537e09cc87fcbd0ef1 450 Pfam PF00083 Sugar (and other) transporter 35 241 3.4E-22 T 06-07-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 BWK49_RS25200 381c8b9546f0b6537e09cc87fcbd0ef1 450 Pfam PF07690 Major Facilitator Superfamily 278 444 4.8E-9 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 BWK49_RS25200 381c8b9546f0b6537e09cc87fcbd0ef1 450 Gene3D G3DSA:1.20.1250.20 258 445 6.5E-15 T 06-07-2017 BWK49_RS25200 381c8b9546f0b6537e09cc87fcbd0ef1 450 Gene3D G3DSA:1.20.1250.20 34 240 5.5E-25 T 06-07-2017 BWK49_RS03960 55569bb6b9114e446e9f38c1f110df06 155 Gene3D G3DSA:2.60.120.10 38 146 1.3E-23 T 06-07-2017 IPR014710 RmlC-like jelly roll fold BWK49_RS03960 55569bb6b9114e446e9f38c1f110df06 155 SUPERFAMILY SSF51182 26 148 6.69E-20 T 06-07-2017 IPR011051 RmlC-like cupin domain BWK49_RS03960 55569bb6b9114e446e9f38c1f110df06 155 Pfam PF07883 Cupin domain 66 130 9.6E-9 T 06-07-2017 IPR013096 Cupin 2, conserved barrel BWK49_RS18635 10991d85f36991e0b3404cd2968d4f1e 207 SUPERFAMILY SSF54909 7 92 6.7E-5 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel BWK49_RS01065 a77fd60ff35f842c7bc63ffccf0e5221 248 Pfam PF12833 Helix-turn-helix domain 171 244 1.9E-20 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 BWK49_RS01065 a77fd60ff35f842c7bc63ffccf0e5221 248 Gene3D G3DSA:2.60.120.10 10 80 1.6E-13 T 06-07-2017 IPR014710 RmlC-like jelly roll fold BWK49_RS01065 a77fd60ff35f842c7bc63ffccf0e5221 248 Gene3D G3DSA:1.10.10.60 144 200 4.0E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS01065 a77fd60ff35f842c7bc63ffccf0e5221 248 SMART SM00342 163 245 3.6E-24 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 BWK49_RS01065 a77fd60ff35f842c7bc63ffccf0e5221 248 SUPERFAMILY SSF51182 8 168 1.78E-19 T 06-07-2017 IPR011051 RmlC-like cupin domain BWK49_RS01065 a77fd60ff35f842c7bc63ffccf0e5221 248 SUPERFAMILY SSF46689 199 245 9.32E-8 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS01065 a77fd60ff35f842c7bc63ffccf0e5221 248 Gene3D G3DSA:1.10.10.60 201 244 5.9E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS01065 a77fd60ff35f842c7bc63ffccf0e5221 248 Pfam PF07883 Cupin domain 14 75 6.9E-9 T 06-07-2017 IPR013096 Cupin 2, conserved barrel BWK49_RS28105 38a8461755566436f1dcc1ed29158718 144 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 25 61 9.7E-12 T 06-07-2017 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal BWK49_RS28105 38a8461755566436f1dcc1ed29158718 144 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 62 125 8.9E-22 T 06-07-2017 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal BWK49_RS28105 38a8461755566436f1dcc1ed29158718 144 SUPERFAMILY SSF50249 13 133 2.91E-36 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS00005 0bd443f8bc998bdf68b40fd4b682aa27 511 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 237 251 1.0E-48 T 06-07-2017 IPR020591 Chromosomal replication control, initiator DnaA-like BWK49_RS00005 0bd443f8bc998bdf68b40fd4b682aa27 511 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 465 484 1.0E-48 T 06-07-2017 IPR020591 Chromosomal replication control, initiator DnaA-like BWK49_RS00005 0bd443f8bc998bdf68b40fd4b682aa27 511 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 205 225 1.0E-48 T 06-07-2017 IPR020591 Chromosomal replication control, initiator DnaA-like BWK49_RS00005 0bd443f8bc998bdf68b40fd4b682aa27 511 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 303 330 1.0E-48 T 06-07-2017 IPR020591 Chromosomal replication control, initiator DnaA-like BWK49_RS00005 0bd443f8bc998bdf68b40fd4b682aa27 511 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 269 283 1.0E-48 T 06-07-2017 IPR020591 Chromosomal replication control, initiator DnaA-like BWK49_RS00005 0bd443f8bc998bdf68b40fd4b682aa27 511 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 10 506 32.294 T 06-07-2017 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 BWK49_RS00005 0bd443f8bc998bdf68b40fd4b682aa27 511 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 44 505 1.3E-148 T 06-07-2017 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 BWK49_RS00005 0bd443f8bc998bdf68b40fd4b682aa27 511 SMART SM00382 204 332 1.7E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS00005 0bd443f8bc998bdf68b40fd4b682aa27 511 Gene3D G3DSA:1.10.8.60 338 407 7.2E-28 T 06-07-2017 BWK49_RS00005 0bd443f8bc998bdf68b40fd4b682aa27 511 SUPERFAMILY SSF48295 403 507 1.31E-30 T 06-07-2017 IPR010921 Trp repressor/replication initiator GO:0043565 BWK49_RS00005 0bd443f8bc998bdf68b40fd4b682aa27 511 Pfam PF00308 Bacterial dnaA protein 172 389 2.3E-103 T 06-07-2017 IPR013317 Chromosomal replication initiator protein DnaA BWK49_RS00005 0bd443f8bc998bdf68b40fd4b682aa27 511 Gene3D G3DSA:1.10.1750.10 413 507 9.8E-34 T 06-07-2017 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 BWK49_RS00005 0bd443f8bc998bdf68b40fd4b682aa27 511 Gene3D G3DSA:3.40.50.300 170 336 1.9E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS00005 0bd443f8bc998bdf68b40fd4b682aa27 511 SMART SM00760 416 484 2.1E-31 T 06-07-2017 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 BWK49_RS00005 0bd443f8bc998bdf68b40fd4b682aa27 511 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 419 484 8.4E-27 T 06-07-2017 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 BWK49_RS00005 0bd443f8bc998bdf68b40fd4b682aa27 511 ProSitePatterns PS01008 DnaA protein signature. 466 484 - T 06-07-2017 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 BWK49_RS00005 0bd443f8bc998bdf68b40fd4b682aa27 511 SUPERFAMILY SSF52540 171 383 1.41E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS20100 3faab064431eb5aaa7e3c3fe7abf635b 169 SUPERFAMILY SSF52833 38 162 8.64E-31 T 06-07-2017 IPR012336 Thioredoxin-like fold BWK49_RS20100 3faab064431eb5aaa7e3c3fe7abf635b 169 Gene3D G3DSA:3.40.30.10 39 166 9.5E-34 T 06-07-2017 IPR012336 Thioredoxin-like fold BWK49_RS20100 3faab064431eb5aaa7e3c3fe7abf635b 169 ProSitePatterns PS00194 Thioredoxin family active site. 61 79 - T 06-07-2017 IPR017937 Thioredoxin, conserved site GO:0045454 BWK49_RS20100 3faab064431eb5aaa7e3c3fe7abf635b 169 Pfam PF00578 AhpC/TSA family 39 139 9.2E-17 T 06-07-2017 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 BWK49_RS12770 0611545af214da64af052b1f2f1434fd 313 SMART SM00729 71 276 1.1E-12 T 06-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 BWK49_RS12770 0611545af214da64af052b1f2f1434fd 313 Gene3D G3DSA:3.20.20.70 38 304 8.2E-69 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 BWK49_RS12770 0611545af214da64af052b1f2f1434fd 313 Hamap MF_00206 Lipoyl synthase [lipA]. 1 307 142.565 T 06-07-2017 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 BWK49_RS12770 0611545af214da64af052b1f2f1434fd 313 SUPERFAMILY SSF102114 35 297 3.4E-65 T 06-07-2017 BWK49_RS12770 0611545af214da64af052b1f2f1434fd 313 Pfam PF04055 Radical SAM superfamily 81 234 2.1E-13 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 BWK49_RS12770 0611545af214da64af052b1f2f1434fd 313 TIGRFAM TIGR00510 lipA: lipoyl synthase 19 302 9.3E-100 T 06-07-2017 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 BWK49_RS12770 0611545af214da64af052b1f2f1434fd 313 Pfam PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family 24 60 1.7E-6 T 06-07-2017 IPR031691 Lipoyl synthase, N-terminal KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 BWK49_RS12770 0611545af214da64af052b1f2f1434fd 313 PIRSF PIRSF005963 4 313 9.5E-126 T 06-07-2017 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 BWK49_RS02565 609bd8702d456c680f0a3bdd53335a62 236 Hamap MF_02036 Gamma-glutamyl-hercynylcysteine sulfoxide hydrolase [egtC]. 1 230 35.394 T 06-07-2017 IPR032889 Gamma-glutamyl-hercynylcysteine sulfoxide hydrolase, Actinobacteria GO:0016811|GO:0052699 KEGG: 00311+3.5.1.11|KEGG: 00340+3.5.1.118|MetaCyc: PWY-7255 BWK49_RS02565 609bd8702d456c680f0a3bdd53335a62 236 TIGRFAM TIGR03442 TIGR03442: ergothioneine biosynthesis protein EgtC 1 230 5.7E-90 T 06-07-2017 IPR017808 Ergothioneine biosynthesis protein EgtC GO:0052699 BWK49_RS02565 609bd8702d456c680f0a3bdd53335a62 236 SUPERFAMILY SSF56235 2 229 1.93E-19 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal BWK49_RS02565 609bd8702d456c680f0a3bdd53335a62 236 Gene3D G3DSA:3.60.20.10 1 229 3.1E-36 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal BWK49_RS02565 609bd8702d456c680f0a3bdd53335a62 236 Pfam PF13522 Glutamine amidotransferase domain 73 201 5.8E-15 T 06-07-2017 BWK49_RS13445 e50ced5adda2c1dedc3e57e0cc588943 318 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 34 266 1.9E-75 T 06-07-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 BWK49_RS13445 e50ced5adda2c1dedc3e57e0cc588943 318 Pfam PF00902 Sec-independent protein translocase protein (TatC) 36 259 6.1E-60 T 06-07-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 BWK49_RS13445 e50ced5adda2c1dedc3e57e0cc588943 318 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 28 281 17.787 T 06-07-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 BWK49_RS13445 e50ced5adda2c1dedc3e57e0cc588943 318 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 33 60 7.1E-41 T 06-07-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 BWK49_RS13445 e50ced5adda2c1dedc3e57e0cc588943 318 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 144 170 7.1E-41 T 06-07-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 BWK49_RS13445 e50ced5adda2c1dedc3e57e0cc588943 318 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 194 222 7.1E-41 T 06-07-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 BWK49_RS13445 e50ced5adda2c1dedc3e57e0cc588943 318 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 126 144 7.1E-41 T 06-07-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 BWK49_RS13445 e50ced5adda2c1dedc3e57e0cc588943 318 ProSitePatterns PS01218 TatC family signature. 194 213 - T 06-07-2017 IPR019820 Sec-independent periplasmic protein translocase, conserved site BWK49_RS00010 739cc0704a985b76a475acbc2a22f7c5 399 SUPERFAMILY SSF55979 262 397 1.33E-26 T 06-07-2017 BWK49_RS00010 739cc0704a985b76a475acbc2a22f7c5 399 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 13 130 5.3E-38 T 06-07-2017 IPR022634 DNA polymerase III, beta chain, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 BWK49_RS00010 739cc0704a985b76a475acbc2a22f7c5 399 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 13 397 4.4E-115 T 06-07-2017 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 BWK49_RS00010 739cc0704a985b76a475acbc2a22f7c5 399 PIRSF PIRSF000804 13 398 1.1E-91 T 06-07-2017 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 BWK49_RS00010 739cc0704a985b76a475acbc2a22f7c5 399 SUPERFAMILY SSF55979 14 130 6.63E-23 T 06-07-2017 BWK49_RS00010 739cc0704a985b76a475acbc2a22f7c5 399 Gene3D G3DSA:3.10.150.10 12 132 8.6E-30 T 06-07-2017 BWK49_RS00010 739cc0704a985b76a475acbc2a22f7c5 399 Gene3D G3DSA:3.10.150.10 134 264 4.9E-30 T 06-07-2017 BWK49_RS00010 739cc0704a985b76a475acbc2a22f7c5 399 SMART SM00480 29 378 1.5E-143 T 06-07-2017 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 BWK49_RS00010 739cc0704a985b76a475acbc2a22f7c5 399 Gene3D G3DSA:3.10.150.10 266 398 3.7E-41 T 06-07-2017 BWK49_RS00010 739cc0704a985b76a475acbc2a22f7c5 399 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 262 374 6.2E-34 T 06-07-2017 IPR022635 DNA polymerase III, beta chain, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 BWK49_RS00010 739cc0704a985b76a475acbc2a22f7c5 399 Pfam PF02767 DNA polymerase III beta subunit, central domain 138 260 1.6E-35 T 06-07-2017 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 BWK49_RS00010 739cc0704a985b76a475acbc2a22f7c5 399 SUPERFAMILY SSF55979 138 263 2.83E-19 T 06-07-2017 BWK49_RS28830 5cf0e9f65116afa8d962d97d8f558998 506 Pfam PF10774 Domain of unknown function (DUF4226) 74 170 1.5E-7 T 06-07-2017 IPR019710 Protein of unknown function DUF4226 BWK49_RS16190 a1c737099e3052ff709cb9933d568b9a 396 Pfam PF00823 PPE family 6 162 4.3E-62 T 06-07-2017 IPR000030 PPE family BWK49_RS16190 a1c737099e3052ff709cb9933d568b9a 396 SUPERFAMILY SSF140459 3 174 4.71E-63 T 06-07-2017 BWK49_RS16190 a1c737099e3052ff709cb9933d568b9a 396 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 308 390 2.1E-15 T 06-07-2017 IPR022171 PPE family, C-terminal BWK49_RS00235 ca54d0162996704b7948f093752d1c9f 105 Pfam PF10921 Protein of unknown function (DUF2710) 2 102 9.3E-54 T 06-07-2017 IPR024296 Protein of unknown function DUF2710 BWK49_RS00235 ca54d0162996704b7948f093752d1c9f 105 ProDom PD071857 MB0031 RV0030/MT0034 2 104 6.0E-44 T 06-07-2017 IPR024296 Protein of unknown function DUF2710 BWK49_RS22095 0a5384a9d193b2788af62e79e85a3cd9 200 Pfam PF16859 Bacterial transcriptional repressor C-terminal 85 192 1.9E-19 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS22095 0a5384a9d193b2788af62e79e85a3cd9 200 SUPERFAMILY SSF48498 86 200 1.03E-20 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS22095 0a5384a9d193b2788af62e79e85a3cd9 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 72 3.2E-15 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS22095 0a5384a9d193b2788af62e79e85a3cd9 200 SUPERFAMILY SSF46689 17 78 3.54E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS22095 0a5384a9d193b2788af62e79e85a3cd9 200 Gene3D G3DSA:1.10.357.10 65 199 9.7E-27 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS22095 0a5384a9d193b2788af62e79e85a3cd9 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 47 70 7.4E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS22095 0a5384a9d193b2788af62e79e85a3cd9 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 39 7.4E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS22095 0a5384a9d193b2788af62e79e85a3cd9 200 Gene3D G3DSA:1.10.10.60 16 64 2.4E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS25485 68befab139069b233636e296716cbf66 265 Gene3D G3DSA:3.10.129.10 164 229 2.0E-7 T 06-07-2017 IPR029069 HotDog domain BWK49_RS25485 68befab139069b233636e296716cbf66 265 SUPERFAMILY SSF54637 156 231 7.7E-14 T 06-07-2017 IPR029069 HotDog domain BWK49_RS25485 68befab139069b233636e296716cbf66 265 SUPERFAMILY SSF54637 15 142 1.81E-20 T 06-07-2017 IPR029069 HotDog domain BWK49_RS25485 68befab139069b233636e296716cbf66 265 Gene3D G3DSA:3.10.129.10 18 140 2.3E-10 T 06-07-2017 IPR029069 HotDog domain BWK49_RS25485 68befab139069b233636e296716cbf66 265 Pfam PF01643 Acyl-ACP thioesterase 16 263 3.2E-66 T 06-07-2017 IPR002864 Acyl-ACP thioesterase GO:0006633|GO:0016790 BWK49_RS21085 50203f5f1191fce472bad729e0df6c6b 266 Pfam PF01012 Electron transfer flavoprotein domain 26 214 1.8E-40 T 06-07-2017 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 BWK49_RS21085 50203f5f1191fce472bad729e0df6c6b 266 PIRSF PIRSF000090 2 266 2.6E-80 T 06-07-2017 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105 BWK49_RS21085 50203f5f1191fce472bad729e0df6c6b 266 SUPERFAMILY SSF52402 3 260 1.4E-65 T 06-07-2017 BWK49_RS21085 50203f5f1191fce472bad729e0df6c6b 266 SMART SM00893 24 219 1.3E-48 T 06-07-2017 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 BWK49_RS21085 50203f5f1191fce472bad729e0df6c6b 266 ProSitePatterns PS01065 Electron transfer flavoprotein beta-subunit signature. 163 183 - T 06-07-2017 IPR000049 Electron transfer flavoprotein, beta-subunit, conserved site GO:0009055 Reactome: R-HSA-611105 BWK49_RS21085 50203f5f1191fce472bad729e0df6c6b 266 Gene3D G3DSA:3.40.50.620 3 265 1.2E-80 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold BWK49_RS02825 31a251b4a73c7f48d158dbac27fc244f 651 Gene3D G3DSA:3.40.50.980 265 423 2.5E-26 T 06-07-2017 BWK49_RS02825 31a251b4a73c7f48d158dbac27fc244f 651 Hamap MF_01123 Acetyl-coenzyme A synthetase [acs]. 7 651 49.954 T 06-07-2017 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118|Reactome: R-HSA-71384 BWK49_RS02825 31a251b4a73c7f48d158dbac27fc244f 651 Gene3D G3DSA:3.40.50.980 77 264 2.4E-39 T 06-07-2017 BWK49_RS02825 31a251b4a73c7f48d158dbac27fc244f 651 SUPERFAMILY SSF56801 26 649 2.49E-173 T 06-07-2017 BWK49_RS02825 31a251b4a73c7f48d158dbac27fc244f 651 Pfam PF13193 AMP-binding enzyme C-terminal domain 539 617 3.4E-25 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS02825 31a251b4a73c7f48d158dbac27fc244f 651 Gene3D G3DSA:2.30.38.10 438 524 9.7E-14 T 06-07-2017 BWK49_RS02825 31a251b4a73c7f48d158dbac27fc244f 651 ProSitePatterns PS00455 Putative AMP-binding domain signature. 259 270 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS02825 31a251b4a73c7f48d158dbac27fc244f 651 Gene3D G3DSA:3.30.300.30 526 631 3.6E-27 T 06-07-2017 BWK49_RS02825 31a251b4a73c7f48d158dbac27fc244f 651 Pfam PF00501 AMP-binding enzyme 85 530 2.1E-95 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS02825 31a251b4a73c7f48d158dbac27fc244f 651 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 26 79 4.6E-21 T 06-07-2017 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118 BWK49_RS02825 31a251b4a73c7f48d158dbac27fc244f 651 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 21 649 8.7E-288 T 06-07-2017 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118|Reactome: R-HSA-71384 BWK49_RS09270 b8d9c191a60be2b0f5a996e757743955 266 Pfam PF00440 Bacterial regulatory proteins, tetR family 28 74 2.6E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS09270 b8d9c191a60be2b0f5a996e757743955 266 SUPERFAMILY SSF48498 88 238 2.45E-22 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS09270 b8d9c191a60be2b0f5a996e757743955 266 Gene3D G3DSA:1.10.357.10 14 239 4.6E-41 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS09270 b8d9c191a60be2b0f5a996e757743955 266 ProSitePatterns PS01081 TetR-type HTH domain signature. 40 71 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site BWK49_RS09270 b8d9c191a60be2b0f5a996e757743955 266 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 90 229 2.3E-11 T 06-07-2017 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 BWK49_RS09270 b8d9c191a60be2b0f5a996e757743955 266 SUPERFAMILY SSF46689 17 82 1.39E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS14425 5e760bc7968110b5bdabaaf2302da7a7 770 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 497 591 8.4E-20 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 BWK49_RS14425 5e760bc7968110b5bdabaaf2302da7a7 770 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 604 750 2.8E-9 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS14425 5e760bc7968110b5bdabaaf2302da7a7 770 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 226 358 1.9E-18 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS14425 5e760bc7968110b5bdabaaf2302da7a7 770 Gene3D G3DSA:1.20.140.10 226 359 1.3E-26 T 06-07-2017 BWK49_RS14425 5e760bc7968110b5bdabaaf2302da7a7 770 Gene3D G3DSA:1.20.140.10 593 757 8.2E-16 T 06-07-2017 BWK49_RS14425 5e760bc7968110b5bdabaaf2302da7a7 770 Gene3D G3DSA:2.40.110.10 496 592 2.9E-30 T 06-07-2017 BWK49_RS14425 5e760bc7968110b5bdabaaf2302da7a7 770 Gene3D G3DSA:1.10.540.10 411 495 1.8E-20 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS14425 5e760bc7968110b5bdabaaf2302da7a7 770 SUPERFAMILY SSF47203 225 358 7.09E-28 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS14425 5e760bc7968110b5bdabaaf2302da7a7 770 SUPERFAMILY SSF47203 604 754 1.08E-8 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS14425 5e760bc7968110b5bdabaaf2302da7a7 770 SUPERFAMILY SSF56645 395 616 2.88E-63 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS14425 5e760bc7968110b5bdabaaf2302da7a7 770 Gene3D G3DSA:1.10.540.10 13 122 1.1E-20 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS14425 5e760bc7968110b5bdabaaf2302da7a7 770 SUPERFAMILY SSF56645 12 196 2.49E-30 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS14425 5e760bc7968110b5bdabaaf2302da7a7 770 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 393 493 5.3E-17 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS14425 5e760bc7968110b5bdabaaf2302da7a7 770 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 13 120 5.1E-21 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS23110 69b9ced25dca71596231171d51a90c7b 282 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 12 272 5.9E-62 T 06-07-2017 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 BWK49_RS23110 69b9ced25dca71596231171d51a90c7b 282 Gene3D G3DSA:1.10.3720.10 12 273 6.9E-37 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS23110 69b9ced25dca71596231171d51a90c7b 282 SUPERFAMILY SSF161098 18 267 7.66E-33 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS23110 69b9ced25dca71596231171d51a90c7b 282 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 82 276 9.8E-25 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS25380 c32857eac012fe6fef431148091be4b7 424 SUPERFAMILY SSF53756 32 413 1.36E-81 T 06-07-2017 BWK49_RS25380 c32857eac012fe6fef431148091be4b7 424 Hamap MF_01695 D-inositol-3-phosphate glycosyltransferase [mshA]. 13 416 50.52 T 06-07-2017 IPR017814 Mycothiol biosynthesis protein, MshA GO:0008375|GO:0010125 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 BWK49_RS25380 c32857eac012fe6fef431148091be4b7 424 TIGRFAM TIGR03449 mycothiol_MshA: D-inositol-3-phosphate glycosyltransferase 14 413 1.6E-199 T 06-07-2017 IPR017814 Mycothiol biosynthesis protein, MshA GO:0008375|GO:0010125 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 BWK49_RS25380 c32857eac012fe6fef431148091be4b7 424 Pfam PF00534 Glycosyl transferases group 1 220 387 2.0E-34 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 BWK49_RS25380 c32857eac012fe6fef431148091be4b7 424 Pfam PF13439 Glycosyltransferase Family 4 33 213 1.6E-31 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 BWK49_RS25380 c32857eac012fe6fef431148091be4b7 424 Gene3D G3DSA:3.40.50.2000 197 387 1.5E-42 T 06-07-2017 BWK49_RS20375 287d1cd1ed610b4358a23120b1debfcd 438 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 166 437 5.3E-106 T 06-07-2017 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 BWK49_RS20375 287d1cd1ed610b4358a23120b1debfcd 438 SMART SM00962 239 438 5.4E-101 T 06-07-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 BWK49_RS20375 287d1cd1ed610b4358a23120b1debfcd 438 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 411 424 - T 06-07-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 BWK49_RS20375 287d1cd1ed610b4358a23120b1debfcd 438 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 165 438 58.792 T 06-07-2017 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 BWK49_RS20375 287d1cd1ed610b4358a23120b1debfcd 438 Pfam PF02881 SRP54-type protein, helical bundle domain 159 218 1.2E-6 T 06-07-2017 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 BWK49_RS20375 287d1cd1ed610b4358a23120b1debfcd 438 Gene3D G3DSA:1.20.120.140 145 224 6.2E-14 T 06-07-2017 BWK49_RS20375 287d1cd1ed610b4358a23120b1debfcd 438 SUPERFAMILY SSF52540 234 437 4.51E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS20375 287d1cd1ed610b4358a23120b1debfcd 438 Pfam PF00448 SRP54-type protein, GTPase domain 239 438 2.8E-73 T 06-07-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 BWK49_RS20375 287d1cd1ed610b4358a23120b1debfcd 438 Gene3D G3DSA:3.40.50.300 233 438 2.4E-72 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS20375 287d1cd1ed610b4358a23120b1debfcd 438 SUPERFAMILY SSF47364 137 216 3.27E-14 T 06-07-2017 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 BWK49_RS20375 287d1cd1ed610b4358a23120b1debfcd 438 SMART SM00382 238 414 1.6E-8 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS20375 287d1cd1ed610b4358a23120b1debfcd 438 SMART SM00963 142 222 8.8E-15 T 06-07-2017 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 BWK49_RS18585 a3b9a7b7562c9b41f4b14fd4e2219f72 401 Pfam PF01264 Chorismate synthase 2 367 4.3E-118 T 06-07-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 BWK49_RS18585 a3b9a7b7562c9b41f4b14fd4e2219f72 401 Gene3D G3DSA:3.60.150.10 2 395 3.4E-155 T 06-07-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 BWK49_RS18585 a3b9a7b7562c9b41f4b14fd4e2219f72 401 ProSitePatterns PS00787 Chorismate synthase signature 1. 8 23 - T 06-07-2017 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 BWK49_RS18585 a3b9a7b7562c9b41f4b14fd4e2219f72 401 ProSitePatterns PS00789 Chorismate synthase signature 3. 341 357 - T 06-07-2017 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 BWK49_RS18585 a3b9a7b7562c9b41f4b14fd4e2219f72 401 TIGRFAM TIGR00033 aroC: chorismate synthase 2 372 2.3E-124 T 06-07-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 BWK49_RS18585 a3b9a7b7562c9b41f4b14fd4e2219f72 401 PIRSF PIRSF001456 1 390 1.6E-125 T 06-07-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 BWK49_RS18585 a3b9a7b7562c9b41f4b14fd4e2219f72 401 Hamap MF_00300 Chorismate synthase [aroC]. 2 374 34.4 T 06-07-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 BWK49_RS18585 a3b9a7b7562c9b41f4b14fd4e2219f72 401 ProSitePatterns PS00788 Chorismate synthase signature 2. 134 150 - T 06-07-2017 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 BWK49_RS18585 a3b9a7b7562c9b41f4b14fd4e2219f72 401 SUPERFAMILY SSF103263 2 389 1.96E-134 T 06-07-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 BWK49_RS01170 c7058dd7617561bfeabd3552e7723839 632 Gene3D G3DSA:2.30.38.10 392 481 1.5E-14 T 06-07-2017 BWK49_RS01170 c7058dd7617561bfeabd3552e7723839 632 Gene3D G3DSA:3.40.50.980 18 188 7.3E-25 T 06-07-2017 BWK49_RS01170 c7058dd7617561bfeabd3552e7723839 632 Gene3D G3DSA:3.40.50.980 189 361 7.6E-25 T 06-07-2017 BWK49_RS01170 c7058dd7617561bfeabd3552e7723839 632 Gene3D G3DSA:3.30.300.30 483 610 6.5E-10 T 06-07-2017 BWK49_RS01170 c7058dd7617561bfeabd3552e7723839 632 Pfam PF00501 AMP-binding enzyme 26 491 1.0E-66 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS01170 c7058dd7617561bfeabd3552e7723839 632 SUPERFAMILY SSF56801 19 615 9.55E-89 T 06-07-2017 BWK49_RS24435 f1173e479faae6956f2d79016981ddc2 124 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 123 39.588 T 06-07-2017 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS24435 f1173e479faae6956f2d79016981ddc2 124 SUPERFAMILY SSF50249 2 123 7.28E-52 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS24435 f1173e479faae6956f2d79016981ddc2 124 Gene3D G3DSA:2.40.50.140 1 123 7.4E-64 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS24435 f1173e479faae6956f2d79016981ddc2 124 ProSitePatterns PS00055 Ribosomal protein S12 signature. 43 50 - T 06-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS24435 f1173e479faae6956f2d79016981ddc2 124 Pfam PF00164 Ribosomal protein S12/S23 3 123 3.8E-43 T 06-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS24435 f1173e479faae6956f2d79016981ddc2 124 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 123 3.6E-67 T 06-07-2017 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS24435 f1173e479faae6956f2d79016981ddc2 124 PIRSF PIRSF002133 1 124 3.8E-54 T 06-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS24435 f1173e479faae6956f2d79016981ddc2 124 PRINTS PR01034 Ribosomal protein S12 signature 77 94 4.6E-58 T 06-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS24435 f1173e479faae6956f2d79016981ddc2 124 PRINTS PR01034 Ribosomal protein S12 signature 42 57 4.6E-58 T 06-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS24435 f1173e479faae6956f2d79016981ddc2 124 PRINTS PR01034 Ribosomal protein S12 signature 58 77 4.6E-58 T 06-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS24435 f1173e479faae6956f2d79016981ddc2 124 PRINTS PR01034 Ribosomal protein S12 signature 94 110 4.6E-58 T 06-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS24435 f1173e479faae6956f2d79016981ddc2 124 PRINTS PR01034 Ribosomal protein S12 signature 27 42 4.6E-58 T 06-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS24435 f1173e479faae6956f2d79016981ddc2 124 PRINTS PR01034 Ribosomal protein S12 signature 110 122 4.6E-58 T 06-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS16830 bd4c2febb0cc81e263ec8d0e7678a52a 262 SUPERFAMILY SSF56784 6 251 1.4E-43 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS16830 bd4c2febb0cc81e263ec8d0e7678a52a 262 Pfam PF13344 Haloacid dehalogenase-like hydrolase 7 97 4.8E-16 T 06-07-2017 IPR006357 HAD-superfamily hydrolase, subfamily IIA BWK49_RS16830 bd4c2febb0cc81e263ec8d0e7678a52a 262 Gene3D G3DSA:3.40.50.10410 78 176 3.1E-20 T 06-07-2017 IPR023215 Nitrophenylphosphatase-like domain BWK49_RS16830 bd4c2febb0cc81e263ec8d0e7678a52a 262 Gene3D G3DSA:3.40.50.1000 177 255 9.1E-33 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS16830 bd4c2febb0cc81e263ec8d0e7678a52a 262 Gene3D G3DSA:3.40.50.1000 5 77 9.1E-33 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS16830 bd4c2febb0cc81e263ec8d0e7678a52a 262 Pfam PF13242 HAD-hyrolase-like 178 250 3.2E-15 T 06-07-2017 BWK49_RS09245 ceca6923acf731a588ab4c295e465895 264 Gene3D G3DSA:3.90.226.10 1 235 1.6E-56 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS09245 ceca6923acf731a588ab4c295e465895 264 Pfam PF00378 Enoyl-CoA hydratase/isomerase 14 227 9.8E-38 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 BWK49_RS09245 ceca6923acf731a588ab4c295e465895 264 SUPERFAMILY SSF52096 1 233 1.24E-57 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS00820 6c2d092259bc5a16a6594a3ea772c110 315 Pfam PF01266 FAD dependent oxidoreductase 2 191 2.2E-22 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 BWK49_RS00820 6c2d092259bc5a16a6594a3ea772c110 315 SUPERFAMILY SSF51905 2 197 3.3E-29 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS00820 6c2d092259bc5a16a6594a3ea772c110 315 SUPERFAMILY SSF51905 277 309 3.3E-29 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS00820 6c2d092259bc5a16a6594a3ea772c110 315 Gene3D G3DSA:3.50.50.60 2 62 2.6E-24 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS00820 6c2d092259bc5a16a6594a3ea772c110 315 Gene3D G3DSA:3.50.50.60 129 196 2.6E-24 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS00820 6c2d092259bc5a16a6594a3ea772c110 315 Gene3D G3DSA:3.50.50.60 269 307 2.6E-24 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS00820 6c2d092259bc5a16a6594a3ea772c110 315 Gene3D G3DSA:3.30.9.10 63 128 8.0E-4 T 06-07-2017 BWK49_RS14345 5887eb6720484d29dbf57a2c907ccf08 746 Gene3D G3DSA:1.10.520.10 443 598 4.9E-65 T 06-07-2017 BWK49_RS14345 5887eb6720484d29dbf57a2c907ccf08 746 Gene3D G3DSA:1.10.520.10 724 745 4.9E-65 T 06-07-2017 BWK49_RS14345 5887eb6720484d29dbf57a2c907ccf08 746 Gene3D G3DSA:1.10.520.10 62 215 1.2E-69 T 06-07-2017 BWK49_RS14345 5887eb6720484d29dbf57a2c907ccf08 746 Gene3D G3DSA:1.10.520.10 249 261 1.2E-69 T 06-07-2017 BWK49_RS14345 5887eb6720484d29dbf57a2c907ccf08 746 SUPERFAMILY SSF48113 36 439 6.04E-144 T 06-07-2017 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 BWK49_RS14345 5887eb6720484d29dbf57a2c907ccf08 746 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 67 80 9.6E-53 T 06-07-2017 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 BWK49_RS14345 5887eb6720484d29dbf57a2c907ccf08 746 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 82 107 9.6E-53 T 06-07-2017 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 BWK49_RS14345 5887eb6720484d29dbf57a2c907ccf08 746 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 490 516 9.6E-53 T 06-07-2017 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 BWK49_RS14345 5887eb6720484d29dbf57a2c907ccf08 746 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 41 63 9.6E-53 T 06-07-2017 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 BWK49_RS14345 5887eb6720484d29dbf57a2c907ccf08 746 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 277 300 9.6E-53 T 06-07-2017 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 BWK49_RS14345 5887eb6720484d29dbf57a2c907ccf08 746 SUPERFAMILY SSF48113 440 745 1.34E-114 T 06-07-2017 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 BWK49_RS14345 5887eb6720484d29dbf57a2c907ccf08 746 ProSitePatterns PS00436 Peroxidases active site signature. 105 116 - T 06-07-2017 IPR019794 Peroxidase, active site GO:0004601|GO:0055114 BWK49_RS14345 5887eb6720484d29dbf57a2c907ccf08 746 Gene3D G3DSA:1.10.420.10 599 721 4.1E-44 T 06-07-2017 BWK49_RS14345 5887eb6720484d29dbf57a2c907ccf08 746 PRINTS PR00458 Haem peroxidase superfamily signature 183 195 4.2E-19 T 06-07-2017 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 BWK49_RS14345 5887eb6720484d29dbf57a2c907ccf08 746 PRINTS PR00458 Haem peroxidase superfamily signature 328 343 4.2E-19 T 06-07-2017 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 BWK49_RS14345 5887eb6720484d29dbf57a2c907ccf08 746 PRINTS PR00458 Haem peroxidase superfamily signature 105 119 4.2E-19 T 06-07-2017 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 BWK49_RS14345 5887eb6720484d29dbf57a2c907ccf08 746 PRINTS PR00458 Haem peroxidase superfamily signature 165 182 4.2E-19 T 06-07-2017 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 BWK49_RS14345 5887eb6720484d29dbf57a2c907ccf08 746 PRINTS PR00458 Haem peroxidase superfamily signature 269 284 4.2E-19 T 06-07-2017 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 BWK49_RS14345 5887eb6720484d29dbf57a2c907ccf08 746 Pfam PF00141 Peroxidase 414 720 4.4E-40 T 06-07-2017 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 BWK49_RS14345 5887eb6720484d29dbf57a2c907ccf08 746 Pfam PF00141 Peroxidase 96 404 3.8E-45 T 06-07-2017 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 BWK49_RS14345 5887eb6720484d29dbf57a2c907ccf08 746 ProSitePatterns PS00435 Peroxidases proximal heme-ligand signature. 269 279 - T 06-07-2017 IPR019793 Peroxidases heam-ligand binding site Reactome: R-HSA-2408557 BWK49_RS14345 5887eb6720484d29dbf57a2c907ccf08 746 Hamap MF_01961 Catalase-peroxidase [katG]. 20 746 40.827 T 06-07-2017 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 BWK49_RS14345 5887eb6720484d29dbf57a2c907ccf08 746 TIGRFAM TIGR00198 cat_per_HPI: catalase/peroxidase HPI 35 745 0.0 T 06-07-2017 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 BWK49_RS14345 5887eb6720484d29dbf57a2c907ccf08 746 Gene3D G3DSA:1.10.420.10 262 284 8.6E-39 T 06-07-2017 BWK49_RS14345 5887eb6720484d29dbf57a2c907ccf08 746 Gene3D G3DSA:1.10.420.10 320 418 8.6E-39 T 06-07-2017 BWK49_RS26120 eef4721e7c73d49da556177705d8cb12 213 SUPERFAMILY SSF51064 129 181 5.36E-13 T 06-07-2017 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 BWK49_RS26120 eef4721e7c73d49da556177705d8cb12 213 ProSitePatterns PS01071 grpE protein signature. 138 179 - T 06-07-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 BWK49_RS26120 eef4721e7c73d49da556177705d8cb12 213 Pfam PF01025 GrpE 48 180 8.3E-29 T 06-07-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 BWK49_RS26120 eef4721e7c73d49da556177705d8cb12 213 PRINTS PR00773 GrpE protein signature 59 75 2.9E-23 T 06-07-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 BWK49_RS26120 eef4721e7c73d49da556177705d8cb12 213 PRINTS PR00773 GrpE protein signature 87 102 2.9E-23 T 06-07-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 BWK49_RS26120 eef4721e7c73d49da556177705d8cb12 213 PRINTS PR00773 GrpE protein signature 135 150 2.9E-23 T 06-07-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 BWK49_RS26120 eef4721e7c73d49da556177705d8cb12 213 PRINTS PR00773 GrpE protein signature 160 179 2.9E-23 T 06-07-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 BWK49_RS26120 eef4721e7c73d49da556177705d8cb12 213 Hamap MF_01151 Protein GrpE [grpE]. 2 181 15.044 T 06-07-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 BWK49_RS26120 eef4721e7c73d49da556177705d8cb12 213 Gene3D G3DSA:3.90.20.20 42 124 1.6E-20 T 06-07-2017 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 BWK49_RS26120 eef4721e7c73d49da556177705d8cb12 213 SUPERFAMILY SSF58014 46 124 3.53E-17 T 06-07-2017 BWK49_RS26120 eef4721e7c73d49da556177705d8cb12 213 Gene3D G3DSA:2.30.22.10 127 181 3.4E-17 T 06-07-2017 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 BWK49_RS23420 bdd9ff66f277b8189e6918617c9d6eec 133 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 9 100 1.5E-10 T 06-07-2017 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 BWK49_RS23420 bdd9ff66f277b8189e6918617c9d6eec 133 SUPERFAMILY SSF53927 3 128 6.73E-39 T 06-07-2017 IPR016193 Cytidine deaminase-like GO:0003824 BWK49_RS23420 bdd9ff66f277b8189e6918617c9d6eec 133 Gene3D G3DSA:3.40.140.10 5 128 2.0E-43 T 06-07-2017 BWK49_RS17710 47b309fa764547d154f72f019d57b366 416 Gene3D G3DSA:3.40.50.2000 2 255 1.3E-56 T 06-07-2017 BWK49_RS17710 47b309fa764547d154f72f019d57b366 416 SUPERFAMILY SSF53756 2 413 1.54E-86 T 06-07-2017 BWK49_RS17710 47b309fa764547d154f72f019d57b366 416 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 4 87 2.4E-8 T 06-07-2017 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 BWK49_RS17710 47b309fa764547d154f72f019d57b366 416 Gene3D G3DSA:3.40.50.2000 256 388 5.4E-9 T 06-07-2017 BWK49_RS18065 d9b36e72d6785ec278f58c36041e069a 930 Pfam PF00196 Bacterial regulatory proteins, luxR family 870 925 1.9E-16 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS18065 d9b36e72d6785ec278f58c36041e069a 930 Pfam PF13191 AAA ATPase domain 16 165 6.2E-19 T 06-07-2017 BWK49_RS18065 d9b36e72d6785ec278f58c36041e069a 930 ProSitePatterns PS00622 LuxR-type HTH domain signature. 886 913 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS18065 d9b36e72d6785ec278f58c36041e069a 930 Gene3D G3DSA:1.10.10.10 865 926 1.4E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS18065 d9b36e72d6785ec278f58c36041e069a 930 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 872 886 8.2E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS18065 d9b36e72d6785ec278f58c36041e069a 930 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 886 902 8.2E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS18065 d9b36e72d6785ec278f58c36041e069a 930 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 902 914 8.2E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS18065 d9b36e72d6785ec278f58c36041e069a 930 SUPERFAMILY SSF52540 10 239 1.39E-10 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS18065 d9b36e72d6785ec278f58c36041e069a 930 SMART SM00421 869 926 2.8E-21 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS18065 d9b36e72d6785ec278f58c36041e069a 930 SUPERFAMILY SSF46894 862 927 1.67E-17 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 BWK49_RS18065 d9b36e72d6785ec278f58c36041e069a 930 Gene3D G3DSA:3.40.50.300 15 156 1.5E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS05840 e90f86e1599b52a402e2e040da8c6186 256 SUPERFAMILY SSF52096 9 251 5.13E-62 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS05840 e90f86e1599b52a402e2e040da8c6186 256 Gene3D G3DSA:3.90.226.10 4 252 2.8E-64 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS05840 e90f86e1599b52a402e2e040da8c6186 256 Pfam PF00378 Enoyl-CoA hydratase/isomerase 15 250 1.6E-38 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 BWK49_RS17520 407834c3e278cce4655011d6e344956c 129 Gene3D G3DSA:1.10.1660.10 6 58 6.5E-22 T 06-07-2017 BWK49_RS17520 407834c3e278cce4655011d6e344956c 129 Pfam PF13411 MerR HTH family regulatory protein 6 71 3.5E-18 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 BWK49_RS17520 407834c3e278cce4655011d6e344956c 129 ProSitePatterns PS00552 MerR-type HTH domain signature. 8 30 - T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 BWK49_RS17520 407834c3e278cce4655011d6e344956c 129 Gene3D G3DSA:1.10.1660.10 59 121 5.9E-12 T 06-07-2017 BWK49_RS17520 407834c3e278cce4655011d6e344956c 129 SUPERFAMILY SSF46955 6 110 3.41E-26 T 06-07-2017 IPR009061 Putative DNA-binding domain BWK49_RS17520 407834c3e278cce4655011d6e344956c 129 SMART SM00422 6 73 5.0E-18 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 BWK49_RS17520 407834c3e278cce4655011d6e344956c 129 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 40 60 7.8E-9 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 BWK49_RS17520 407834c3e278cce4655011d6e344956c 129 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 6 17 7.8E-9 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 BWK49_RS17520 407834c3e278cce4655011d6e344956c 129 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 17 30 7.8E-9 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 BWK49_RS22100 252e54a5ba0153e669fb4bd4f0da2ea7 378 SUPERFAMILY SSF56112 29 333 8.67E-33 T 06-07-2017 IPR011009 Protein kinase-like domain BWK49_RS22100 252e54a5ba0153e669fb4bd4f0da2ea7 378 Pfam PF01636 Phosphotransferase enzyme family 72 287 5.0E-23 T 06-07-2017 IPR002575 Aminoglycoside phosphotransferase BWK49_RS22100 252e54a5ba0153e669fb4bd4f0da2ea7 378 Gene3D G3DSA:3.90.1200.10 153 334 7.8E-20 T 06-07-2017 BWK49_RS18145 ac23b088311a068299ccaab6fe2420cf 438 Pfam PF00266 Aminotransferase class-V 35 406 9.0E-134 T 06-07-2017 IPR000192 Aminotransferase class V domain BWK49_RS18145 ac23b088311a068299ccaab6fe2420cf 438 SUPERFAMILY SSF53383 12 414 1.06E-112 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase BWK49_RS18145 ac23b088311a068299ccaab6fe2420cf 438 Gene3D G3DSA:3.90.1150.10 294 411 6.4E-27 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 BWK49_RS18145 ac23b088311a068299ccaab6fe2420cf 438 Gene3D G3DSA:3.40.640.10 46 293 1.6E-78 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 BWK49_RS18145 ac23b088311a068299ccaab6fe2420cf 438 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 227 246 - T 06-07-2017 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site BWK49_RS18145 ac23b088311a068299ccaab6fe2420cf 438 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 15 417 1.6E-166 T 06-07-2017 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 BWK49_RS11190 8eb132760ab7d3e9122f27d219ff5680 146 Pfam PF02566 OsmC-like protein 46 139 2.2E-15 T 06-07-2017 IPR003718 OsmC/Ohr family BWK49_RS11190 8eb132760ab7d3e9122f27d219ff5680 146 SUPERFAMILY SSF82784 7 137 1.96E-26 T 06-07-2017 IPR003718 OsmC/Ohr family BWK49_RS11190 8eb132760ab7d3e9122f27d219ff5680 146 TIGRFAM TIGR03562 osmo_induc_OsmC: peroxiredoxin, OsmC subfamily 6 143 1.8E-44 T 06-07-2017 IPR019904 Peroxiredoxin OsmC GO:0004601|GO:0006979 KEGG: 00480+1.11.1.15 BWK49_RS11190 8eb132760ab7d3e9122f27d219ff5680 146 Gene3D G3DSA:3.30.300.20 6 145 9.6E-38 T 06-07-2017 IPR015946 K homology domain-like, alpha/beta BWK49_RS00725 f0c978986ef344f2869b326a6c4a3a71 272 Pfam PF07728 AAA domain (dynein-related subfamily) 37 171 1.8E-34 T 06-07-2017 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 BWK49_RS00725 f0c978986ef344f2869b326a6c4a3a71 272 SUPERFAMILY SSF52540 25 211 9.46E-36 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS00725 f0c978986ef344f2869b326a6c4a3a71 272 Gene3D G3DSA:3.40.50.300 27 188 2.4E-32 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS00725 f0c978986ef344f2869b326a6c4a3a71 272 Pfam PF08406 CbbQ/NirQ/NorQ C-terminal 184 267 9.1E-26 T 06-07-2017 IPR013615 CbbQ/NirQ/NorQ, C-terminal BWK49_RS27135 3efcbdc4408a382a81149e064749258e 570 Pfam PF00920 Dehydratase family 44 567 1.1E-206 T 06-07-2017 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 BWK49_RS27135 3efcbdc4408a382a81149e064749258e 570 SUPERFAMILY SSF143975 8 391 2.48E-136 T 06-07-2017 BWK49_RS27135 3efcbdc4408a382a81149e064749258e 570 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 14 570 45.511 T 06-07-2017 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 BWK49_RS27135 3efcbdc4408a382a81149e064749258e 570 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 28 568 1.3E-213 T 06-07-2017 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 BWK49_RS27135 3efcbdc4408a382a81149e064749258e 570 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 478 489 - T 06-07-2017 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 BWK49_RS27135 3efcbdc4408a382a81149e064749258e 570 SUPERFAMILY SSF52016 392 569 4.32E-54 T 06-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel BWK49_RS27135 3efcbdc4408a382a81149e064749258e 570 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 132 142 - T 06-07-2017 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 BWK49_RS12220 eb588b34d0d9d2a9c574c08ddb0eac11 555 SUPERFAMILY SSF56014 162 320 8.37E-45 T 06-07-2017 BWK49_RS12220 eb588b34d0d9d2a9c574c08ddb0eac11 555 SUPERFAMILY SSF55124 292 423 5.72E-18 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 BWK49_RS12220 eb588b34d0d9d2a9c574c08ddb0eac11 555 PRINTS PR00397 Sirohaem Fe-binding site signature 412 430 1.1E-8 T 06-07-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 BWK49_RS12220 eb588b34d0d9d2a9c574c08ddb0eac11 555 PRINTS PR00397 Sirohaem Fe-binding site signature 461 479 1.1E-8 T 06-07-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 BWK49_RS12220 eb588b34d0d9d2a9c574c08ddb0eac11 555 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 338 400 1.1E-10 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 BWK49_RS12220 eb588b34d0d9d2a9c574c08ddb0eac11 555 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 92 152 5.6E-12 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 BWK49_RS12220 eb588b34d0d9d2a9c574c08ddb0eac11 555 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 414 534 1.1E-8 T 06-07-2017 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 BWK49_RS12220 eb588b34d0d9d2a9c574c08ddb0eac11 555 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 162 313 7.0E-38 T 06-07-2017 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 BWK49_RS12220 eb588b34d0d9d2a9c574c08ddb0eac11 555 SUPERFAMILY SSF56014 408 555 1.44E-33 T 06-07-2017 BWK49_RS12220 eb588b34d0d9d2a9c574c08ddb0eac11 555 SUPERFAMILY SSF55124 11 161 5.72E-36 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 BWK49_RS12220 eb588b34d0d9d2a9c574c08ddb0eac11 555 Gene3D G3DSA:3.30.413.10 162 311 1.9E-40 T 06-07-2017 BWK49_RS12220 eb588b34d0d9d2a9c574c08ddb0eac11 555 Gene3D G3DSA:3.90.480.10 91 159 5.6E-37 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 BWK49_RS12220 eb588b34d0d9d2a9c574c08ddb0eac11 555 Gene3D G3DSA:3.90.480.10 328 403 5.6E-37 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 BWK49_RS12220 eb588b34d0d9d2a9c574c08ddb0eac11 555 Gene3D G3DSA:3.30.413.10 411 554 1.7E-32 T 06-07-2017 BWK49_RS12220 eb588b34d0d9d2a9c574c08ddb0eac11 555 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 461 477 - T 06-07-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 BWK49_RS26985 d097b511fe5b07d762a5a79ac63c6814 220 Gene3D G3DSA:3.40.50.150 64 203 1.8E-9 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS26985 d097b511fe5b07d762a5a79ac63c6814 220 SUPERFAMILY SSF53335 63 210 1.53E-12 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS08295 e6109475b020ae35bbde5c5b0c970903 864 TIGRFAM TIGR03550 F420_cofG: 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofG subunit 90 419 2.0E-144 T 06-07-2017 IPR019939 CofG family GO:0009108|GO:0016765|GO:0051539 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 BWK49_RS08295 e6109475b020ae35bbde5c5b0c970903 864 TIGRFAM TIGR03551 F420_cofH: 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofH subunit 518 861 1.2E-161 T 06-07-2017 IPR019940 CofH family GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 BWK49_RS08295 e6109475b020ae35bbde5c5b0c970903 864 SUPERFAMILY SSF102114 45 396 3.92E-37 T 06-07-2017 BWK49_RS08295 e6109475b020ae35bbde5c5b0c970903 864 TIGRFAM TIGR00423 TIGR00423: radical SAM domain protein, CofH subfamily 552 860 8.3E-113 T 06-07-2017 IPR020050 FO synthase, subunit 2 GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 BWK49_RS08295 e6109475b020ae35bbde5c5b0c970903 864 Pfam PF04055 Radical SAM superfamily 560 727 4.6E-13 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 BWK49_RS08295 e6109475b020ae35bbde5c5b0c970903 864 Pfam PF04055 Radical SAM superfamily 97 280 3.6E-11 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 BWK49_RS08295 e6109475b020ae35bbde5c5b0c970903 864 SUPERFAMILY SSF102114 519 827 2.88E-46 T 06-07-2017 BWK49_RS08295 e6109475b020ae35bbde5c5b0c970903 864 Gene3D G3DSA:3.20.20.70 46 382 1.4E-70 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 BWK49_RS08295 e6109475b020ae35bbde5c5b0c970903 864 Gene3D G3DSA:3.20.20.70 520 854 3.0E-72 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 BWK49_RS08295 e6109475b020ae35bbde5c5b0c970903 864 Hamap MF_01612 FO synthase subunit 2 [cofH]. 504 863 50.674 T 06-07-2017 IPR019940 CofH family GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 BWK49_RS08295 e6109475b020ae35bbde5c5b0c970903 864 SMART SM00729 93 330 3.8E-6 T 06-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 BWK49_RS08295 e6109475b020ae35bbde5c5b0c970903 864 Hamap MF_01611 FO synthase subunit 1 [cofG]. 89 421 51.321 T 06-07-2017 IPR019939 CofG family GO:0009108|GO:0016765|GO:0051539 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 BWK49_RS26690 dc85df6882eab22bd9692139eab6d673 611 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 288 455 7.1E-14 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS26690 dc85df6882eab22bd9692139eab6d673 611 Pfam PF12418 Acyl-CoA dehydrogenase N terminal 3 34 7.6E-9 T 06-07-2017 IPR020953 Acyl-CoA dehydrogenase, N-terminal, bacteria BWK49_RS26690 dc85df6882eab22bd9692139eab6d673 611 Gene3D G3DSA:2.40.110.10 161 273 8.1E-26 T 06-07-2017 BWK49_RS26690 dc85df6882eab22bd9692139eab6d673 611 SUPERFAMILY SSF47203 292 473 4.19E-30 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS26690 dc85df6882eab22bd9692139eab6d673 611 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 162 272 6.9E-18 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 BWK49_RS26690 dc85df6882eab22bd9692139eab6d673 611 SUPERFAMILY SSF56645 36 294 5.5E-44 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS26690 dc85df6882eab22bd9692139eab6d673 611 Gene3D G3DSA:1.10.540.10 36 148 2.8E-5 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS26690 dc85df6882eab22bd9692139eab6d673 611 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 475 607 4.8E-32 T 06-07-2017 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain BWK49_RS26690 dc85df6882eab22bd9692139eab6d673 611 Gene3D G3DSA:1.20.140.10 274 467 4.1E-40 T 06-07-2017 BWK49_RS03530 1f3865d55a66446e3a63857bb251fc6d 407 Gene3D G3DSA:1.10.630.10 9 401 2.7E-113 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS03530 1f3865d55a66446e3a63857bb251fc6d 407 PRINTS PR00359 B-class P450 signature 192 214 9.4E-49 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS03530 1f3865d55a66446e3a63857bb251fc6d 407 PRINTS PR00359 B-class P450 signature 339 348 9.4E-49 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS03530 1f3865d55a66446e3a63857bb251fc6d 407 PRINTS PR00359 B-class P450 signature 348 359 9.4E-49 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS03530 1f3865d55a66446e3a63857bb251fc6d 407 PRINTS PR00359 B-class P450 signature 147 162 9.4E-49 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS03530 1f3865d55a66446e3a63857bb251fc6d 407 PRINTS PR00359 B-class P450 signature 84 95 9.4E-49 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS03530 1f3865d55a66446e3a63857bb251fc6d 407 PRINTS PR00359 B-class P450 signature 290 317 9.4E-49 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS03530 1f3865d55a66446e3a63857bb251fc6d 407 PRINTS PR00359 B-class P450 signature 318 333 9.4E-49 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS03530 1f3865d55a66446e3a63857bb251fc6d 407 PRINTS PR00359 B-class P450 signature 130 146 9.4E-49 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS03530 1f3865d55a66446e3a63857bb251fc6d 407 PRINTS PR00359 B-class P450 signature 273 284 9.4E-49 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS03530 1f3865d55a66446e3a63857bb251fc6d 407 PRINTS PR00385 P450 superfamily signature 348 359 2.6E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS03530 1f3865d55a66446e3a63857bb251fc6d 407 PRINTS PR00385 P450 superfamily signature 339 348 2.6E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS03530 1f3865d55a66446e3a63857bb251fc6d 407 PRINTS PR00385 P450 superfamily signature 273 284 2.6E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS03530 1f3865d55a66446e3a63857bb251fc6d 407 PRINTS PR00385 P450 superfamily signature 238 255 2.6E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS03530 1f3865d55a66446e3a63857bb251fc6d 407 Pfam PF00067 Cytochrome P450 180 259 2.0E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS03530 1f3865d55a66446e3a63857bb251fc6d 407 Pfam PF00067 Cytochrome P450 270 368 4.8E-18 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS03530 1f3865d55a66446e3a63857bb251fc6d 407 SUPERFAMILY SSF48264 28 401 2.36E-87 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS03530 1f3865d55a66446e3a63857bb251fc6d 407 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 341 350 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 BWK49_RS24770 91411b4cfb73fd6acb2c5634f4657ba3 294 Pfam PF00561 alpha/beta hydrolase fold 24 127 7.2E-27 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS24770 91411b4cfb73fd6acb2c5634f4657ba3 294 PRINTS PR00412 Epoxide hydrolase signature 29 47 4.9E-5 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS24770 91411b4cfb73fd6acb2c5634f4657ba3 294 PRINTS PR00412 Epoxide hydrolase signature 252 274 4.9E-5 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS24770 91411b4cfb73fd6acb2c5634f4657ba3 294 PRINTS PR00111 Alpha/beta hydrolase fold signature 92 105 6.5E-17 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS24770 91411b4cfb73fd6acb2c5634f4657ba3 294 PRINTS PR00111 Alpha/beta hydrolase fold signature 106 119 6.5E-17 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS24770 91411b4cfb73fd6acb2c5634f4657ba3 294 PRINTS PR00111 Alpha/beta hydrolase fold signature 48 63 6.5E-17 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS24770 91411b4cfb73fd6acb2c5634f4657ba3 294 PRINTS PR00111 Alpha/beta hydrolase fold signature 221 235 6.5E-17 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS24770 91411b4cfb73fd6acb2c5634f4657ba3 294 SUPERFAMILY SSF53474 3 276 2.13E-65 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS24770 91411b4cfb73fd6acb2c5634f4657ba3 294 Gene3D G3DSA:3.40.50.1820 3 276 6.2E-68 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS28770 7ab1a8f8e84a63ed0b72102be3dad6d4 77 SUPERFAMILY SSF52833 3 71 3.48E-16 T 06-07-2017 IPR012336 Thioredoxin-like fold BWK49_RS28770 7ab1a8f8e84a63ed0b72102be3dad6d4 77 Gene3D G3DSA:3.40.30.10 3 76 4.1E-24 T 06-07-2017 IPR012336 Thioredoxin-like fold BWK49_RS28770 7ab1a8f8e84a63ed0b72102be3dad6d4 77 TIGRFAM TIGR02194 GlrX_NrdH: glutaredoxin-like protein NrdH 4 74 4.6E-30 T 06-07-2017 IPR011909 Glutaredoxin-like protein NrdH GO:0045454 BWK49_RS28770 7ab1a8f8e84a63ed0b72102be3dad6d4 77 Pfam PF00462 Glutaredoxin 4 57 2.8E-15 T 06-07-2017 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 BWK49_RS18905 888d38840256ef292111a28e8a9e76fd 316 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 21 302 2.7E-85 T 06-07-2017 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 BWK49_RS27430 e97e8cbce661e22b0c4f32570b0407b3 474 PIRSF PIRSF000204 1 473 2.5E-201 T 06-07-2017 IPR012136 NADP transhydrogenase, beta subunit GO:0008750|GO:0016021|GO:0050661|GO:0055114 KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 BWK49_RS27430 e97e8cbce661e22b0c4f32570b0407b3 474 Pfam PF02233 NAD(P) transhydrogenase beta subunit 8 469 6.0E-173 T 06-07-2017 IPR012136 NADP transhydrogenase, beta subunit GO:0008750|GO:0016021|GO:0050661|GO:0055114 KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 BWK49_RS27430 e97e8cbce661e22b0c4f32570b0407b3 474 Gene3D G3DSA:3.40.50.1220 298 472 1.6E-84 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain BWK49_RS27430 e97e8cbce661e22b0c4f32570b0407b3 474 SUPERFAMILY SSF52467 299 472 4.58E-72 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain BWK49_RS06095 14087833d716d054a5ec677cf3d15511 388 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 233 381 1.2E-37 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS06095 14087833d716d054a5ec677cf3d15511 388 Gene3D G3DSA:1.20.140.10 223 387 6.8E-58 T 06-07-2017 BWK49_RS06095 14087833d716d054a5ec677cf3d15511 388 Gene3D G3DSA:2.40.110.10 122 222 8.6E-30 T 06-07-2017 BWK49_RS06095 14087833d716d054a5ec677cf3d15511 388 SUPERFAMILY SSF56645 1 246 5.5E-63 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS06095 14087833d716d054a5ec677cf3d15511 388 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 220 4.6E-22 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 BWK49_RS06095 14087833d716d054a5ec677cf3d15511 388 Gene3D G3DSA:1.10.540.10 1 119 2.1E-32 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS06095 14087833d716d054a5ec677cf3d15511 388 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 340 359 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 BWK49_RS06095 14087833d716d054a5ec677cf3d15511 388 SUPERFAMILY SSF47203 231 386 1.11E-47 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS06095 14087833d716d054a5ec677cf3d15511 388 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 119 4.5E-25 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS22145 2d605e7f4f8077066cc52beabaf36eff 700 SMART SM01060 25 414 5.9E-273 T 06-07-2017 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 BWK49_RS22145 2d605e7f4f8077066cc52beabaf36eff 700 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 356 364 - T 06-07-2017 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 BWK49_RS22145 2d605e7f4f8077066cc52beabaf36eff 700 Pfam PF06628 Catalase-related immune-responsive 440 503 2.0E-20 T 06-07-2017 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 BWK49_RS22145 2d605e7f4f8077066cc52beabaf36eff 700 SUPERFAMILY SSF56634 6 509 4.45E-215 T 06-07-2017 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 BWK49_RS22145 2d605e7f4f8077066cc52beabaf36eff 700 PIRSF PIRSF038927 1 698 0.0 T 06-07-2017 IPR024712 Catalase, mono-functional, haem-containing, clade 2 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 BWK49_RS22145 2d605e7f4f8077066cc52beabaf36eff 700 Pfam PF01965 DJ-1/PfpI family 535 649 1.5E-8 T 06-07-2017 IPR002818 DJ-1/PfpI BWK49_RS22145 2d605e7f4f8077066cc52beabaf36eff 700 PRINTS PR00067 Catalase signature 343 369 8.3E-72 T 06-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 BWK49_RS22145 2d605e7f4f8077066cc52beabaf36eff 700 PRINTS PR00067 Catalase signature 38 61 8.3E-72 T 06-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 BWK49_RS22145 2d605e7f4f8077066cc52beabaf36eff 700 PRINTS PR00067 Catalase signature 142 160 8.3E-72 T 06-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 BWK49_RS22145 2d605e7f4f8077066cc52beabaf36eff 700 PRINTS PR00067 Catalase signature 102 120 8.3E-72 T 06-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 BWK49_RS22145 2d605e7f4f8077066cc52beabaf36eff 700 PRINTS PR00067 Catalase signature 123 140 8.3E-72 T 06-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 BWK49_RS22145 2d605e7f4f8077066cc52beabaf36eff 700 PRINTS PR00067 Catalase signature 311 338 8.3E-72 T 06-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 BWK49_RS22145 2d605e7f4f8077066cc52beabaf36eff 700 SUPERFAMILY SSF52317 532 693 4.58E-19 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like BWK49_RS22145 2d605e7f4f8077066cc52beabaf36eff 700 ProSitePatterns PS00438 Catalase proximal active site signature. 61 77 - T 06-07-2017 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 BWK49_RS22145 2d605e7f4f8077066cc52beabaf36eff 700 Pfam PF00199 Catalase 25 409 1.7E-177 T 06-07-2017 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 BWK49_RS22145 2d605e7f4f8077066cc52beabaf36eff 700 Gene3D G3DSA:2.40.180.10 8 381 2.0E-181 T 06-07-2017 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 BWK49_RS22145 2d605e7f4f8077066cc52beabaf36eff 700 Gene3D G3DSA:3.40.50.880 534 699 5.1E-45 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like BWK49_RS15025 37c04aaeb26abf1c67fdf128b26c79b3 388 Gene3D G3DSA:1.20.140.10 220 376 3.7E-31 T 06-07-2017 BWK49_RS15025 37c04aaeb26abf1c67fdf128b26c79b3 388 SUPERFAMILY SSF56645 25 232 1.83E-27 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS15025 37c04aaeb26abf1c67fdf128b26c79b3 388 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 226 372 2.3E-31 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS15025 37c04aaeb26abf1c67fdf128b26c79b3 388 Gene3D G3DSA:1.10.540.10 18 115 3.2E-4 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS15025 37c04aaeb26abf1c67fdf128b26c79b3 388 Gene3D G3DSA:2.40.110.10 119 219 2.3E-13 T 06-07-2017 BWK49_RS15025 37c04aaeb26abf1c67fdf128b26c79b3 388 SUPERFAMILY SSF47203 226 372 7.57E-27 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS15025 37c04aaeb26abf1c67fdf128b26c79b3 388 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 119 213 2.4E-13 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 BWK49_RS25640 cfd4485e13bed5b5aac317384581fc0b 352 Pfam PF06500 Alpha/beta hydrolase of unknown function (DUF1100) 44 308 1.4E-8 T 06-07-2017 IPR010520 UPF0255 family BWK49_RS25640 cfd4485e13bed5b5aac317384581fc0b 352 Gene3D G3DSA:3.40.50.1820 115 347 2.1E-19 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS25640 cfd4485e13bed5b5aac317384581fc0b 352 SUPERFAMILY SSF53474 21 346 1.02E-31 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS23385 dd550a2d0267920a3f37a808fdaf5c4d 327 SUPERFAMILY SSF53300 87 288 7.37E-28 T 06-07-2017 IPR002035 von Willebrand factor, type A BWK49_RS23385 dd550a2d0267920a3f37a808fdaf5c4d 327 Gene3D G3DSA:3.40.50.410 89 290 2.1E-19 T 06-07-2017 IPR002035 von Willebrand factor, type A BWK49_RS23385 dd550a2d0267920a3f37a808fdaf5c4d 327 Pfam PF13519 von Willebrand factor type A domain 92 202 4.3E-20 T 06-07-2017 IPR002035 von Willebrand factor, type A BWK49_RS23385 dd550a2d0267920a3f37a808fdaf5c4d 327 SMART SM00327 89 281 7.0E-20 T 06-07-2017 IPR002035 von Willebrand factor, type A BWK49_RS08990 021916ce7ab169ab07e5ad5d74531c8d 417 Gene3D G3DSA:3.65.10.10 22 221 6.6E-65 T 06-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 BWK49_RS08990 021916ce7ab169ab07e5ad5d74531c8d 417 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 406 2.9E-117 T 06-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 BWK49_RS08990 021916ce7ab169ab07e5ad5d74531c8d 417 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 3 415 2.1E-170 T 06-07-2017 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 BWK49_RS08990 021916ce7ab169ab07e5ad5d74531c8d 417 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 2 416 41.871 T 06-07-2017 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 BWK49_RS08990 021916ce7ab169ab07e5ad5d74531c8d 417 SUPERFAMILY SSF55205 4 416 3.6E-132 T 06-07-2017 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 BWK49_RS08990 021916ce7ab169ab07e5ad5d74531c8d 417 Gene3D G3DSA:3.65.10.10 222 416 6.4E-52 T 06-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 BWK49_RS18285 561fe452a9fb52036cce4037b320305a 543 Pfam PF00501 AMP-binding enzyme 48 443 6.7E-65 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS18285 561fe452a9fb52036cce4037b320305a 543 SUPERFAMILY SSF56801 46 541 1.7E-122 T 06-07-2017 BWK49_RS18285 561fe452a9fb52036cce4037b320305a 543 Pfam PF13193 AMP-binding enzyme C-terminal domain 452 531 6.1E-24 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS18285 561fe452a9fb52036cce4037b320305a 543 Gene3D G3DSA:3.30.300.30 438 540 6.7E-35 T 06-07-2017 BWK49_RS18285 561fe452a9fb52036cce4037b320305a 543 Gene3D G3DSA:3.40.50.980 206 367 2.1E-29 T 06-07-2017 BWK49_RS18285 561fe452a9fb52036cce4037b320305a 543 ProSitePatterns PS00455 Putative AMP-binding domain signature. 199 210 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS18285 561fe452a9fb52036cce4037b320305a 543 Gene3D G3DSA:2.30.38.10 368 436 2.5E-14 T 06-07-2017 BWK49_RS18285 561fe452a9fb52036cce4037b320305a 543 Gene3D G3DSA:3.40.50.980 46 205 8.1E-24 T 06-07-2017 BWK49_RS01225 5a9960098e95ac389ccf541856caa09b 107 SUPERFAMILY SSF46785 3 99 4.94E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS01225 5a9960098e95ac389ccf541856caa09b 107 Gene3D G3DSA:1.10.10.10 9 104 1.3E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS01225 5a9960098e95ac389ccf541856caa09b 107 SMART SM00418 8 86 8.8E-24 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 BWK49_RS01225 5a9960098e95ac389ccf541856caa09b 107 Pfam PF01022 Bacterial regulatory protein, arsR family 15 60 8.1E-14 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 BWK49_RS01225 5a9960098e95ac389ccf541856caa09b 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 10 25 5.9E-10 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 BWK49_RS01225 5a9960098e95ac389ccf541856caa09b 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 42 57 5.9E-10 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 BWK49_RS01225 5a9960098e95ac389ccf541856caa09b 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 57 72 5.9E-10 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 BWK49_RS20195 5d78ea42e56dc3093e6af3831ac2a701 271 Pfam PF00889 Elongation factor TS 67 270 1.6E-65 T 06-07-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 BWK49_RS20195 5d78ea42e56dc3093e6af3831ac2a701 271 Gene3D G3DSA:1.10.8.10 3 55 1.9E-22 T 06-07-2017 BWK49_RS20195 5d78ea42e56dc3093e6af3831ac2a701 271 ProSitePatterns PS01126 Elongation factor Ts signature 1. 12 27 - T 06-07-2017 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 BWK49_RS20195 5d78ea42e56dc3093e6af3831ac2a701 271 Gene3D G3DSA:1.10.286.20 190 233 2.7E-19 T 06-07-2017 BWK49_RS20195 5d78ea42e56dc3093e6af3831ac2a701 271 SUPERFAMILY SSF54713 57 88 3.19E-39 T 06-07-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 BWK49_RS20195 5d78ea42e56dc3093e6af3831ac2a701 271 SUPERFAMILY SSF54713 173 269 3.19E-39 T 06-07-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 BWK49_RS20195 5d78ea42e56dc3093e6af3831ac2a701 271 Gene3D G3DSA:3.30.479.20 144 185 3.7E-21 T 06-07-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 BWK49_RS20195 5d78ea42e56dc3093e6af3831ac2a701 271 Gene3D G3DSA:3.30.479.20 234 269 3.7E-21 T 06-07-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 BWK49_RS20195 5d78ea42e56dc3093e6af3831ac2a701 271 ProSitePatterns PS01127 Elongation factor Ts signature 2. 71 81 - T 06-07-2017 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 BWK49_RS20195 5d78ea42e56dc3093e6af3831ac2a701 271 Gene3D G3DSA:3.30.479.20 57 140 4.5E-15 T 06-07-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 BWK49_RS20195 5d78ea42e56dc3093e6af3831ac2a701 271 Hamap MF_00050 Elongation factor Ts [tsf]. 1 271 65.944 T 06-07-2017 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 BWK49_RS20195 5d78ea42e56dc3093e6af3831ac2a701 271 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 3 270 1.2E-75 T 06-07-2017 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 BWK49_RS20195 5d78ea42e56dc3093e6af3831ac2a701 271 SUPERFAMILY SSF46934 5 55 2.33E-14 T 06-07-2017 IPR009060 UBA-like GO:0005515 BWK49_RS16750 1aa44fc7d58b5573976e8f30491a2570 338 SUPERFAMILY SSF51735 3 251 1.37E-60 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS16750 1aa44fc7d58b5573976e8f30491a2570 338 Pfam PF00106 short chain dehydrogenase 3 189 1.6E-45 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS16750 1aa44fc7d58b5573976e8f30491a2570 338 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.6E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS16750 1aa44fc7d58b5573976e8f30491a2570 338 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 204 224 1.6E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS16750 1aa44fc7d58b5573976e8f30491a2570 338 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 1.6E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS16750 1aa44fc7d58b5573976e8f30491a2570 338 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 1.6E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS16750 1aa44fc7d58b5573976e8f30491a2570 338 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 1.6E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS16750 1aa44fc7d58b5573976e8f30491a2570 338 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 138 166 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS16750 1aa44fc7d58b5573976e8f30491a2570 338 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 189 6.1E-4 T 06-07-2017 BWK49_RS16750 1aa44fc7d58b5573976e8f30491a2570 338 Gene3D G3DSA:3.40.50.720 3 240 2.8E-58 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS15975 ee6b0a057c32eae7a1d51d5f7d2e8573 248 Pfam PF03861 ANTAR domain 187 239 2.8E-17 T 06-07-2017 IPR005561 ANTAR domain GO:0003723 BWK49_RS15975 ee6b0a057c32eae7a1d51d5f7d2e8573 248 SMART SM01012 184 239 8.3E-19 T 06-07-2017 IPR005561 ANTAR domain GO:0003723 BWK49_RS15975 ee6b0a057c32eae7a1d51d5f7d2e8573 248 SUPERFAMILY SSF52172 153 239 1.74E-9 T 06-07-2017 IPR011006 CheY-like superfamily BWK49_RS15975 ee6b0a057c32eae7a1d51d5f7d2e8573 248 Pfam PF08448 PAS fold 20 137 3.3E-8 T 06-07-2017 IPR013656 PAS fold-4 BWK49_RS15975 ee6b0a057c32eae7a1d51d5f7d2e8573 248 Gene3D G3DSA:1.10.10.10 187 242 7.8E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS15975 ee6b0a057c32eae7a1d51d5f7d2e8573 248 Gene3D G3DSA:3.30.450.20 19 136 3.1E-6 T 06-07-2017 BWK49_RS01815 ebcce16b174017b28bdb28eba44bc240 130 Gene3D G3DSA:3.30.1050.10 5 117 7.1E-21 T 06-07-2017 IPR003033 SCP2 sterol-binding domain BWK49_RS01815 ebcce16b174017b28bdb28eba44bc240 130 SUPERFAMILY SSF55718 1 129 4.24E-29 T 06-07-2017 IPR003033 SCP2 sterol-binding domain BWK49_RS01815 ebcce16b174017b28bdb28eba44bc240 130 Pfam PF02036 SCP-2 sterol transfer family 20 112 2.9E-12 T 06-07-2017 IPR003033 SCP2 sterol-binding domain BWK49_RS08955 c43e1fbf34e17d976f760ecc5d4e174c 446 SUPERFAMILY SSF81573 60 118 1.31E-8 T 06-07-2017 IPR028987 F-type ATP synthase subunit B-like, membrane domain BWK49_RS08955 c43e1fbf34e17d976f760ecc5d4e174c 446 Pfam PF00430 ATP synthase B/B' CF(0) 3 132 1.3E-17 T 06-07-2017 IPR002146 ATPase, F0 complex, subunit B/B', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 BWK49_RS08955 c43e1fbf34e17d976f760ecc5d4e174c 446 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 276 444 2.6E-17 T 06-07-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 BWK49_RS08955 c43e1fbf34e17d976f760ecc5d4e174c 446 Gene3D G3DSA:1.10.520.20 277 351 4.2E-5 T 06-07-2017 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210 BWK49_RS08955 c43e1fbf34e17d976f760ecc5d4e174c 446 Hamap MF_01416 ATP synthase subunit delta [atpD]. 267 446 13.986 T 06-07-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 BWK49_RS08955 c43e1fbf34e17d976f760ecc5d4e174c 446 PRINTS PR00125 ATP synthase delta subunit signature 404 419 8.3E-8 T 06-07-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 BWK49_RS08955 c43e1fbf34e17d976f760ecc5d4e174c 446 PRINTS PR00125 ATP synthase delta subunit signature 419 437 8.3E-8 T 06-07-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 BWK49_RS08955 c43e1fbf34e17d976f760ecc5d4e174c 446 PRINTS PR00125 ATP synthase delta subunit signature 271 290 8.3E-8 T 06-07-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 BWK49_RS08955 c43e1fbf34e17d976f760ecc5d4e174c 446 Hamap MF_01398 ATP synthase subunit b [atpF]. 1 154 9.995 T 06-07-2017 IPR002146 ATPase, F0 complex, subunit B/B', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 BWK49_RS08955 c43e1fbf34e17d976f760ecc5d4e174c 446 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 7 154 1.5E-19 T 06-07-2017 IPR005864 ATPase, F0 complex, subunit B, bacterial GO:0015078|GO:0015986|GO:0045263 BWK49_RS08955 c43e1fbf34e17d976f760ecc5d4e174c 446 SUPERFAMILY SSF47928 277 338 8.37E-5 T 06-07-2017 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210 BWK49_RS08955 c43e1fbf34e17d976f760ecc5d4e174c 446 Pfam PF00213 ATP synthase delta (OSCP) subunit 277 444 7.3E-28 T 06-07-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 BWK49_RS08955 c43e1fbf34e17d976f760ecc5d4e174c 446 Gene3D G3DSA:1.20.5.620 62 118 1.2E-6 T 06-07-2017 IPR028987 F-type ATP synthase subunit B-like, membrane domain BWK49_RS17355 4cf3cd36d08d4a88fd6dcf212fe3637b 349 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 35 342 3.1E-86 T 06-07-2017 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 BWK49_RS17355 4cf3cd36d08d4a88fd6dcf212fe3637b 349 SUPERFAMILY SSF142754 34 342 5.62E-101 T 06-07-2017 BWK49_RS17355 4cf3cd36d08d4a88fd6dcf212fe3637b 349 Pfam PF02445 Quinolinate synthetase A protein 37 341 6.9E-107 T 06-07-2017 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 BWK49_RS17355 4cf3cd36d08d4a88fd6dcf212fe3637b 349 Hamap MF_00568 Quinolinate synthase A [nadA]. 32 342 42.284 T 06-07-2017 IPR023066 Quinolinate synthase A, type 2 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342 BWK49_RS23270 ff6d1bef7b2e76b3e6460620804acd8d 305 SUPERFAMILY SSF53474 35 199 1.35E-25 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS23270 ff6d1bef7b2e76b3e6460620804acd8d 305 SUPERFAMILY SSF53474 245 278 1.35E-25 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS23270 ff6d1bef7b2e76b3e6460620804acd8d 305 Gene3D G3DSA:3.40.50.1820 13 304 3.0E-33 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS23270 ff6d1bef7b2e76b3e6460620804acd8d 305 Pfam PF10503 Esterase PHB depolymerase 44 178 1.1E-9 T 06-07-2017 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 BWK49_RS10030 a489fa5d26359bd27ef8d4f9ca63fa9e 680 Gene3D G3DSA:3.40.50.620 326 578 5.7E-57 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold BWK49_RS10030 a489fa5d26359bd27ef8d4f9ca63fa9e 680 Gene3D G3DSA:3.40.50.620 619 647 5.7E-57 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold BWK49_RS10030 a489fa5d26359bd27ef8d4f9ca63fa9e 680 SUPERFAMILY SSF56317 11 296 5.23E-50 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 BWK49_RS10030 a489fa5d26359bd27ef8d4f9ca63fa9e 680 Pfam PF00795 Carbon-nitrogen hydrolase 13 281 3.1E-15 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 BWK49_RS10030 a489fa5d26359bd27ef8d4f9ca63fa9e 680 PIRSF PIRSF006630 9 670 5.3E-178 T 06-07-2017 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|Reactome: R-HSA-196807 BWK49_RS10030 a489fa5d26359bd27ef8d4f9ca63fa9e 680 SUPERFAMILY SSF52402 616 648 9.04E-60 T 06-07-2017 BWK49_RS10030 a489fa5d26359bd27ef8d4f9ca63fa9e 680 SUPERFAMILY SSF52402 324 575 9.04E-60 T 06-07-2017 BWK49_RS10030 a489fa5d26359bd27ef8d4f9ca63fa9e 680 Pfam PF02540 NAD synthase 348 520 7.8E-23 T 06-07-2017 IPR022310 NAD/GMP synthase BWK49_RS10030 a489fa5d26359bd27ef8d4f9ca63fa9e 680 Gene3D G3DSA:3.60.110.10 12 294 2.4E-54 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 BWK49_RS26765 05a8b77fab93ff4921c551d0194b4521 456 SUPERFAMILY SSF140459 5 175 1.62E-60 T 06-07-2017 BWK49_RS26765 05a8b77fab93ff4921c551d0194b4521 456 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 305 374 1.2E-10 T 06-07-2017 IPR022171 PPE family, C-terminal BWK49_RS26765 05a8b77fab93ff4921c551d0194b4521 456 Pfam PF00823 PPE family 8 164 9.8E-61 T 06-07-2017 IPR000030 PPE family BWK49_RS27335 1d8c418e4031e16f2c86c7b9086e8e2e 406 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 350 359 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 BWK49_RS27335 1d8c418e4031e16f2c86c7b9086e8e2e 406 PRINTS PR00359 B-class P450 signature 141 157 1.9E-23 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS27335 1d8c418e4031e16f2c86c7b9086e8e2e 406 PRINTS PR00359 B-class P450 signature 357 368 1.9E-23 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS27335 1d8c418e4031e16f2c86c7b9086e8e2e 406 PRINTS PR00359 B-class P450 signature 158 173 1.9E-23 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS27335 1d8c418e4031e16f2c86c7b9086e8e2e 406 PRINTS PR00359 B-class P450 signature 282 293 1.9E-23 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS27335 1d8c418e4031e16f2c86c7b9086e8e2e 406 PRINTS PR00359 B-class P450 signature 299 326 1.9E-23 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS27335 1d8c418e4031e16f2c86c7b9086e8e2e 406 PRINTS PR00359 B-class P450 signature 327 342 1.9E-23 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS27335 1d8c418e4031e16f2c86c7b9086e8e2e 406 PRINTS PR00359 B-class P450 signature 348 357 1.9E-23 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS27335 1d8c418e4031e16f2c86c7b9086e8e2e 406 SUPERFAMILY SSF48264 10 406 5.63E-71 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS27335 1d8c418e4031e16f2c86c7b9086e8e2e 406 Pfam PF00067 Cytochrome P450 190 377 9.2E-19 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS27335 1d8c418e4031e16f2c86c7b9086e8e2e 406 Gene3D G3DSA:1.10.630.10 8 406 1.7E-82 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS24420 087207a8c82dd6745027c9e2d6b39559 396 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 53 68 - T 06-07-2017 IPR031157 Tr-type G domain, conserved site BWK49_RS24420 087207a8c82dd6745027c9e2d6b39559 396 Gene3D G3DSA:3.40.50.300 4 210 4.3E-69 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS24420 087207a8c82dd6745027c9e2d6b39559 396 SUPERFAMILY SSF50465 304 396 4.89E-35 T 06-07-2017 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal BWK49_RS24420 087207a8c82dd6745027c9e2d6b39559 396 Gene3D G3DSA:2.40.30.10 302 395 3.0E-45 T 06-07-2017 BWK49_RS24420 087207a8c82dd6745027c9e2d6b39559 396 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 2 396 2.1E-216 T 06-07-2017 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 BWK49_RS24420 087207a8c82dd6745027c9e2d6b39559 396 Gene3D G3DSA:2.40.30.10 211 300 1.3E-36 T 06-07-2017 BWK49_RS24420 087207a8c82dd6745027c9e2d6b39559 396 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 396 58.974 T 06-07-2017 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 BWK49_RS24420 087207a8c82dd6745027c9e2d6b39559 396 PRINTS PR00315 GTP-binding elongation factor signature 14 27 5.8E-24 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 BWK49_RS24420 087207a8c82dd6745027c9e2d6b39559 396 PRINTS PR00315 GTP-binding elongation factor signature 133 142 5.8E-24 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 BWK49_RS24420 087207a8c82dd6745027c9e2d6b39559 396 PRINTS PR00315 GTP-binding elongation factor signature 96 107 5.8E-24 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 BWK49_RS24420 087207a8c82dd6745027c9e2d6b39559 396 PRINTS PR00315 GTP-binding elongation factor signature 80 90 5.8E-24 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 BWK49_RS24420 087207a8c82dd6745027c9e2d6b39559 396 PRINTS PR00315 GTP-binding elongation factor signature 60 68 5.8E-24 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 BWK49_RS24420 087207a8c82dd6745027c9e2d6b39559 396 Pfam PF00009 Elongation factor Tu GTP binding domain 10 202 1.1E-58 T 06-07-2017 BWK49_RS24420 087207a8c82dd6745027c9e2d6b39559 396 SUPERFAMILY SSF52540 9 227 1.59E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS24420 087207a8c82dd6745027c9e2d6b39559 396 Pfam PF03144 Elongation factor Tu domain 2 226 296 1.7E-17 T 06-07-2017 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 BWK49_RS24420 087207a8c82dd6745027c9e2d6b39559 396 Pfam PF03143 Elongation factor Tu C-terminal domain 301 394 9.8E-32 T 06-07-2017 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal BWK49_RS24420 087207a8c82dd6745027c9e2d6b39559 396 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 156 4.0E-14 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 BWK49_RS24420 087207a8c82dd6745027c9e2d6b39559 396 SUPERFAMILY SSF50447 206 303 2.91E-30 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain BWK49_RS09185 1708739c90aa65358a7219624c755cae 142 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 9 89 2.4E-6 T 06-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 BWK49_RS09185 1708739c90aa65358a7219624c755cae 142 SUPERFAMILY SSF50475 7 140 2.43E-21 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 BWK49_RS09185 1708739c90aa65358a7219624c755cae 142 Gene3D G3DSA:2.30.110.10 5 138 7.5E-22 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 BWK49_RS24680 bf7825d7169a3a8ca3c06a2d561abd25 171 SUPERFAMILY SSF55469 1 171 1.2E-46 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 BWK49_RS24680 bf7825d7169a3a8ca3c06a2d561abd25 171 Pfam PF00881 Nitroreductase family 68 145 2.2E-9 T 06-07-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 BWK49_RS24680 bf7825d7169a3a8ca3c06a2d561abd25 171 Pfam PF00881 Nitroreductase family 9 60 1.4E-14 T 06-07-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 BWK49_RS24680 bf7825d7169a3a8ca3c06a2d561abd25 171 Gene3D G3DSA:3.40.109.10 1 171 4.8E-45 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 BWK49_RS09135 7a7d7b7cd6a211d11ed32803f33f17fc 259 Pfam PF01138 3' exoribonuclease family, domain 1 12 142 1.2E-24 T 06-07-2017 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 BWK49_RS09135 7a7d7b7cd6a211d11ed32803f33f17fc 259 ProSitePatterns PS01277 Ribonuclease PH signature. 118 131 - T 06-07-2017 IPR018336 Ribonuclease PH, conserved site BWK49_RS09135 7a7d7b7cd6a211d11ed32803f33f17fc 259 Hamap MF_00564 Ribonuclease PH [rph]. 3 240 46.267 T 06-07-2017 IPR002381 Ribonuclease phosphorolytic, bacterial-type GO:0000049|GO:0004549|GO:0008033 BWK49_RS09135 7a7d7b7cd6a211d11ed32803f33f17fc 259 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 4 239 1.6E-105 T 06-07-2017 IPR002381 Ribonuclease phosphorolytic, bacterial-type GO:0000049|GO:0004549|GO:0008033 BWK49_RS09135 7a7d7b7cd6a211d11ed32803f33f17fc 259 SUPERFAMILY SSF55666 157 244 5.63E-22 T 06-07-2017 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 BWK49_RS09135 7a7d7b7cd6a211d11ed32803f33f17fc 259 Pfam PF03725 3' exoribonuclease family, domain 2 161 226 1.2E-9 T 06-07-2017 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 BWK49_RS09135 7a7d7b7cd6a211d11ed32803f33f17fc 259 SUPERFAMILY SSF54211 3 184 6.07E-43 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold BWK49_RS09135 7a7d7b7cd6a211d11ed32803f33f17fc 259 Gene3D G3DSA:3.30.230.70 5 241 7.6E-32 T 06-07-2017 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 BWK49_RS13515 a85389441cdac74a99e46881eded259f 497 Gene3D G3DSA:3.40.1010.10 4 136 4.7E-32 T 06-07-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 BWK49_RS13515 a85389441cdac74a99e46881eded259f 497 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 10 24 - T 06-07-2017 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 BWK49_RS13515 a85389441cdac74a99e46881eded259f 497 SUPERFAMILY SSF53790 4 241 5.1E-41 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 BWK49_RS13515 a85389441cdac74a99e46881eded259f 497 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 103 135 - T 06-07-2017 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 BWK49_RS13515 a85389441cdac74a99e46881eded259f 497 SUPERFAMILY SSF53790 250 492 8.11E-49 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 BWK49_RS13515 a85389441cdac74a99e46881eded259f 497 TIGRFAM TIGR01467 cobI_cbiL: precorrin-2 C(20)-methyltransferase 5 236 6.9E-65 T 06-07-2017 IPR006364 Precorrin-2 C(20)-methyltransferase domain GO:0008757|GO:0009236 BWK49_RS13515 a85389441cdac74a99e46881eded259f 497 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 255 459 8.9E-32 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 BWK49_RS13515 a85389441cdac74a99e46881eded259f 497 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 7 219 2.7E-42 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 BWK49_RS13515 a85389441cdac74a99e46881eded259f 497 TIGRFAM TIGR01466 cobJ_cbiH: precorrin-3B C17-methyltransferase 255 496 4.4E-80 T 06-07-2017 IPR006363 Precorrin-3B C17-methyltransferase domain GO:0008168|GO:0009236 BWK49_RS13515 a85389441cdac74a99e46881eded259f 497 Gene3D G3DSA:3.30.950.10 364 476 8.2E-12 T 06-07-2017 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 BWK49_RS13515 a85389441cdac74a99e46881eded259f 497 Gene3D G3DSA:3.40.1010.10 253 363 9.1E-27 T 06-07-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 BWK49_RS16130 22826a84d89ac20395fbd3179dbc60d5 773 Gene3D G3DSA:3.40.50.1000 581 723 1.5E-43 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS16130 22826a84d89ac20395fbd3179dbc60d5 773 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 215 755 3.3E-174 T 06-07-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 BWK49_RS16130 22826a84d89ac20395fbd3179dbc60d5 773 SUPERFAMILY SSF81665 706 711 1.31E-9 T 06-07-2017 BWK49_RS16130 22826a84d89ac20395fbd3179dbc60d5 773 SUPERFAMILY SSF81665 365 457 1.31E-9 T 06-07-2017 BWK49_RS16130 22826a84d89ac20395fbd3179dbc60d5 773 SUPERFAMILY SSF81665 217 268 1.31E-9 T 06-07-2017 BWK49_RS16130 22826a84d89ac20395fbd3179dbc60d5 773 Gene3D G3DSA:3.40.1110.10 454 481 4.6E-4 T 06-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 BWK49_RS16130 22826a84d89ac20395fbd3179dbc60d5 773 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 465 471 - T 06-07-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 BWK49_RS16130 22826a84d89ac20395fbd3179dbc60d5 773 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 237 730 3.2E-78 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 BWK49_RS16130 22826a84d89ac20395fbd3179dbc60d5 773 Gene3D G3DSA:2.70.150.10 217 365 3.8E-25 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 BWK49_RS16130 22826a84d89ac20395fbd3179dbc60d5 773 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 214 756 3.3E-154 T 06-07-2017 BWK49_RS16130 22826a84d89ac20395fbd3179dbc60d5 773 PRINTS PR00941 Cadmium-transporting ATPase signature 269 285 6.3E-10 T 06-07-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 BWK49_RS16130 22826a84d89ac20395fbd3179dbc60d5 773 PRINTS PR00941 Cadmium-transporting ATPase signature 330 346 6.3E-10 T 06-07-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 BWK49_RS16130 22826a84d89ac20395fbd3179dbc60d5 773 PRINTS PR00941 Cadmium-transporting ATPase signature 349 363 6.3E-10 T 06-07-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 BWK49_RS16130 22826a84d89ac20395fbd3179dbc60d5 773 PRINTS PR00941 Cadmium-transporting ATPase signature 249 269 6.3E-10 T 06-07-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 BWK49_RS16130 22826a84d89ac20395fbd3179dbc60d5 773 Pfam PF00122 E1-E2 ATPase 235 454 2.5E-56 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 BWK49_RS16130 22826a84d89ac20395fbd3179dbc60d5 773 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 677 689 6.9E-27 T 06-07-2017 BWK49_RS16130 22826a84d89ac20395fbd3179dbc60d5 773 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 314 328 6.9E-27 T 06-07-2017 BWK49_RS16130 22826a84d89ac20395fbd3179dbc60d5 773 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 653 672 6.9E-27 T 06-07-2017 BWK49_RS16130 22826a84d89ac20395fbd3179dbc60d5 773 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 463 477 6.9E-27 T 06-07-2017 BWK49_RS16130 22826a84d89ac20395fbd3179dbc60d5 773 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 579 590 6.9E-27 T 06-07-2017 BWK49_RS16130 22826a84d89ac20395fbd3179dbc60d5 773 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 601 611 6.9E-27 T 06-07-2017 BWK49_RS16130 22826a84d89ac20395fbd3179dbc60d5 773 SUPERFAMILY SSF81653 267 364 3.53E-23 T 06-07-2017 BWK49_RS16130 22826a84d89ac20395fbd3179dbc60d5 773 Pfam PF00702 haloacid dehalogenase-like hydrolase 460 667 6.0E-39 T 06-07-2017 BWK49_RS16130 22826a84d89ac20395fbd3179dbc60d5 773 SUPERFAMILY SSF56784 462 481 4.37E-50 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS16130 22826a84d89ac20395fbd3179dbc60d5 773 SUPERFAMILY SSF56784 517 752 4.37E-50 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS16130 22826a84d89ac20395fbd3179dbc60d5 773 Gene3D G3DSA:3.40.1110.10 482 580 3.4E-18 T 06-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 BWK49_RS22880 46f70b26c32be7271a5329dcaa86bf41 473 Pfam PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain 5 271 7.4E-83 T 06-07-2017 IPR004255 O-acyltransferase, WSD1, N-terminal GO:0004144|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 BWK49_RS22880 46f70b26c32be7271a5329dcaa86bf41 473 Pfam PF06974 Protein of unknown function (DUF1298) 325 467 1.8E-17 T 06-07-2017 IPR009721 O-acyltransferase WSD1, C-terminal GO:0004144 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 BWK49_RS22880 46f70b26c32be7271a5329dcaa86bf41 473 TIGRFAM TIGR02946 acyl_WS_DGAT: acyltransferase, WS/DGAT/MGAT 5 470 2.1E-144 T 06-07-2017 IPR014292 Acyltransferase, WS/DGAT/MGAT GO:0016746|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 BWK49_RS22880 46f70b26c32be7271a5329dcaa86bf41 473 SUPERFAMILY SSF52777 5 149 5.67E-6 T 06-07-2017 BWK49_RS23845 3dc6e2bf0bc6cd510eac52f0b6228960 154 Pfam PF00583 Acetyltransferase (GNAT) family 53 129 2.5E-19 T 06-07-2017 IPR000182 GNAT domain GO:0008080 BWK49_RS23845 3dc6e2bf0bc6cd510eac52f0b6228960 154 Gene3D G3DSA:3.40.630.30 6 151 6.0E-32 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase BWK49_RS23845 3dc6e2bf0bc6cd510eac52f0b6228960 154 SUPERFAMILY SSF55729 7 150 7.98E-31 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase BWK49_RS23845 3dc6e2bf0bc6cd510eac52f0b6228960 154 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 15 148 2.6E-39 T 06-07-2017 IPR006464 Ribosomal-protein-alanine acetyltransferase GO:0006474|GO:0016407 BWK49_RS04165 7062bc7f2f5371ccf58ae00fb6476e05 377 Gene3D G3DSA:1.10.1200.80 263 338 1.5E-22 T 06-07-2017 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 BWK49_RS04165 7062bc7f2f5371ccf58ae00fb6476e05 377 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 3 330 2.0E-129 T 06-07-2017 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 BWK49_RS04165 7062bc7f2f5371ccf58ae00fb6476e05 377 Gene3D G3DSA:3.20.20.70 8 257 1.1E-83 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 BWK49_RS04165 7062bc7f2f5371ccf58ae00fb6476e05 377 SUPERFAMILY SSF51395 11 328 1.04E-78 T 06-07-2017 BWK49_RS04165 7062bc7f2f5371ccf58ae00fb6476e05 377 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 102 120 - T 06-07-2017 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 BWK49_RS04165 7062bc7f2f5371ccf58ae00fb6476e05 377 PIRSF PIRSF006621 1 341 2.5E-123 T 06-07-2017 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 BWK49_RS04165 7062bc7f2f5371ccf58ae00fb6476e05 377 Pfam PF01207 Dihydrouridine synthase (Dus) 13 326 1.4E-115 T 06-07-2017 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 BWK49_RS27600 920708dad05a2cf8e50452e914a3a09e 203 Gene3D G3DSA:3.40.630.30 2 201 1.1E-41 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase BWK49_RS27600 920708dad05a2cf8e50452e914a3a09e 203 SUPERFAMILY SSF55729 1 88 1.67E-18 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase BWK49_RS27600 920708dad05a2cf8e50452e914a3a09e 203 SUPERFAMILY SSF55729 123 196 1.67E-18 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase BWK49_RS27600 920708dad05a2cf8e50452e914a3a09e 203 Pfam PF00583 Acetyltransferase (GNAT) family 121 178 5.8E-7 T 06-07-2017 IPR000182 GNAT domain GO:0008080 BWK49_RS16785 58c1aa5cc6b3f1bd7c0101c317e36c90 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 29 69 5.5E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS16785 58c1aa5cc6b3f1bd7c0101c317e36c90 210 Gene3D G3DSA:1.10.10.60 15 72 3.5E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS16785 58c1aa5cc6b3f1bd7c0101c317e36c90 210 SUPERFAMILY SSF48498 95 205 3.42E-26 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS16785 58c1aa5cc6b3f1bd7c0101c317e36c90 210 Pfam PF16925 Bacterial transcriptional repressor C-terminal 95 206 3.7E-45 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS16785 58c1aa5cc6b3f1bd7c0101c317e36c90 210 Gene3D G3DSA:1.10.357.10 73 205 2.0E-25 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS16785 58c1aa5cc6b3f1bd7c0101c317e36c90 210 SUPERFAMILY SSF46689 14 88 6.16E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS06020 88bcca969216d60149fb4583ae030caa 807 SUPERFAMILY SSF89796 7 376 8.37E-75 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS06020 88bcca969216d60149fb4583ae030caa 807 Pfam PF02515 CoA-transferase family III 396 776 2.7E-104 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 BWK49_RS06020 88bcca969216d60149fb4583ae030caa 807 Pfam PF02515 CoA-transferase family III 10 373 6.6E-66 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 BWK49_RS06020 88bcca969216d60149fb4583ae030caa 807 Gene3D G3DSA:3.40.50.10540 309 376 8.3E-63 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS06020 88bcca969216d60149fb4583ae030caa 807 Gene3D G3DSA:3.40.50.10540 708 799 1.1E-92 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS06020 88bcca969216d60149fb4583ae030caa 807 Gene3D G3DSA:3.40.50.10540 393 611 1.1E-92 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS06020 88bcca969216d60149fb4583ae030caa 807 Gene3D G3DSA:3.40.50.10540 8 226 8.3E-63 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS06020 88bcca969216d60149fb4583ae030caa 807 Gene3D G3DSA:3.30.1540.10 243 308 5.1E-12 T 06-07-2017 BWK49_RS06020 88bcca969216d60149fb4583ae030caa 807 Gene3D G3DSA:3.30.1540.10 618 707 2.0E-29 T 06-07-2017 BWK49_RS06020 88bcca969216d60149fb4583ae030caa 807 SUPERFAMILY SSF89796 393 799 6.28E-112 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS09105 3ec2e83ac3c5a4cf2f3c188d468c00fa 101 Pfam PF02617 ATP-dependent Clp protease adaptor protein ClpS 26 95 7.7E-21 T 06-07-2017 IPR003769 Adaptor protein ClpS, core GO:0030163 Reactome: R-HSA-983168 BWK49_RS09105 3ec2e83ac3c5a4cf2f3c188d468c00fa 101 Hamap MF_00302 ATP-dependent Clp protease adapter protein ClpS [clpS]. 6 101 16.906 T 06-07-2017 IPR022935 ATP-dependent Clp protease adaptor protein ClpS BWK49_RS09105 3ec2e83ac3c5a4cf2f3c188d468c00fa 101 Gene3D G3DSA:3.30.1390.10 7 100 1.3E-28 T 06-07-2017 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like BWK49_RS09105 3ec2e83ac3c5a4cf2f3c188d468c00fa 101 SUPERFAMILY SSF54736 25 98 4.71E-23 T 06-07-2017 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like BWK49_RS16515 f2beabe3bba7da432b0ff5dd1c139a68 283 PIRSF PIRSF003073 21 274 2.7E-73 T 06-07-2017 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein BWK49_RS16515 f2beabe3bba7da432b0ff5dd1c139a68 283 SMART SM00382 120 253 7.6E-6 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS16515 f2beabe3bba7da432b0ff5dd1c139a68 283 Pfam PF01695 IstB-like ATP binding protein 76 251 4.8E-54 T 06-07-2017 IPR002611 IstB-like ATP-binding protein GO:0005524 BWK49_RS16515 f2beabe3bba7da432b0ff5dd1c139a68 283 Gene3D G3DSA:3.40.50.300 89 252 2.3E-25 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS16515 f2beabe3bba7da432b0ff5dd1c139a68 283 SUPERFAMILY SSF52540 90 260 1.56E-23 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS16295 f2beabe3bba7da432b0ff5dd1c139a68 283 PIRSF PIRSF003073 21 274 2.7E-73 T 06-07-2017 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein BWK49_RS16295 f2beabe3bba7da432b0ff5dd1c139a68 283 SMART SM00382 120 253 7.6E-6 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS16295 f2beabe3bba7da432b0ff5dd1c139a68 283 Pfam PF01695 IstB-like ATP binding protein 76 251 4.8E-54 T 06-07-2017 IPR002611 IstB-like ATP-binding protein GO:0005524 BWK49_RS16295 f2beabe3bba7da432b0ff5dd1c139a68 283 Gene3D G3DSA:3.40.50.300 89 252 2.3E-25 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS16295 f2beabe3bba7da432b0ff5dd1c139a68 283 SUPERFAMILY SSF52540 90 260 1.56E-23 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS11350 858d47f9a3a3e2fcd4ec55f9693a33ff 355 PIRSF PIRSF001361 1 355 7.5E-155 T 06-07-2017 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 BWK49_RS11350 858d47f9a3a3e2fcd4ec55f9693a33ff 355 SUPERFAMILY SSF51569 14 353 6.8E-127 T 06-07-2017 BWK49_RS11350 858d47f9a3a3e2fcd4ec55f9693a33ff 355 TIGRFAM TIGR00034 aroFGH: 3-deoxy-7-phosphoheptulonate synthase 14 354 4.6E-156 T 06-07-2017 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 BWK49_RS11350 858d47f9a3a3e2fcd4ec55f9693a33ff 355 Pfam PF00793 DAHP synthetase I family 51 343 2.5E-95 T 06-07-2017 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 BWK49_RS11350 858d47f9a3a3e2fcd4ec55f9693a33ff 355 Gene3D G3DSA:3.20.20.70 16 355 2.4E-144 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 BWK49_RS08645 c94fe359cd07fec68feccba323e6ed89 663 SUPERFAMILY SSF103473 268 440 3.53E-70 T 06-07-2017 IPR020846 Major facilitator superfamily domain BWK49_RS08645 c94fe359cd07fec68feccba323e6ed89 663 SUPERFAMILY SSF103473 25 218 3.53E-70 T 06-07-2017 IPR020846 Major facilitator superfamily domain BWK49_RS08645 c94fe359cd07fec68feccba323e6ed89 663 SUPERFAMILY SSF103473 483 501 3.53E-70 T 06-07-2017 IPR020846 Major facilitator superfamily domain BWK49_RS08645 c94fe359cd07fec68feccba323e6ed89 663 Pfam PF07690 Major Facilitator Superfamily 40 430 6.2E-56 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 BWK49_RS08645 c94fe359cd07fec68feccba323e6ed89 663 Gene3D G3DSA:1.20.1250.20 33 216 6.7E-37 T 06-07-2017 BWK49_RS08645 c94fe359cd07fec68feccba323e6ed89 663 Gene3D G3DSA:1.20.1250.20 282 443 1.2E-28 T 06-07-2017 BWK49_RS08645 c94fe359cd07fec68feccba323e6ed89 663 Gene3D G3DSA:1.20.1250.20 476 499 1.2E-28 T 06-07-2017 BWK49_RS08645 c94fe359cd07fec68feccba323e6ed89 663 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 37 442 7.9E-86 T 06-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 BWK49_RS23480 d3b8057366d5b3012c820dd5cf64818e 375 Gene3D G3DSA:2.30.40.10 335 370 1.2E-6 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 BWK49_RS23480 d3b8057366d5b3012c820dd5cf64818e 375 Gene3D G3DSA:2.30.40.10 13 52 7.2E-7 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 BWK49_RS23480 d3b8057366d5b3012c820dd5cf64818e 375 Gene3D G3DSA:3.20.20.140 53 334 7.5E-99 T 06-07-2017 BWK49_RS23480 d3b8057366d5b3012c820dd5cf64818e 375 Pfam PF01979 Amidohydrolase family 48 374 1.4E-36 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 BWK49_RS23480 d3b8057366d5b3012c820dd5cf64818e 375 SUPERFAMILY SSF51338 346 374 2.8E-10 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 BWK49_RS23480 d3b8057366d5b3012c820dd5cf64818e 375 SUPERFAMILY SSF51338 4 51 2.8E-10 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 BWK49_RS23480 d3b8057366d5b3012c820dd5cf64818e 375 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 42 372 7.9E-77 T 06-07-2017 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 BWK49_RS23480 d3b8057366d5b3012c820dd5cf64818e 375 PIRSF PIRSF038994 38 375 2.1E-105 T 06-07-2017 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 BWK49_RS23480 d3b8057366d5b3012c820dd5cf64818e 375 SUPERFAMILY SSF51556 52 344 3.81E-85 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS19220 5bcd0d9b623abad8904500944cb43a0f 487 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 253 260 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 BWK49_RS19220 5bcd0d9b623abad8904500944cb43a0f 487 Gene3D G3DSA:3.40.309.10 266 457 7.7E-66 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 BWK49_RS19220 5bcd0d9b623abad8904500944cb43a0f 487 Pfam PF00171 Aldehyde dehydrogenase family 24 482 2.6E-151 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 BWK49_RS19220 5bcd0d9b623abad8904500944cb43a0f 487 SUPERFAMILY SSF53720 9 485 6.68E-147 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 BWK49_RS19220 5bcd0d9b623abad8904500944cb43a0f 487 Gene3D G3DSA:3.40.605.10 13 265 7.0E-75 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 BWK49_RS18490 5c65246d06f4e78fe402822ad0a856ea 319 Gene3D G3DSA:3.40.50.1370 149 294 9.9E-45 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 BWK49_RS18490 5c65246d06f4e78fe402822ad0a856ea 319 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 160 305 6.1E-20 T 06-07-2017 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 BWK49_RS18490 5c65246d06f4e78fe402822ad0a856ea 319 SUPERFAMILY SSF53671 2 307 1.83E-90 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 BWK49_RS18490 5c65246d06f4e78fe402822ad0a856ea 319 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 3 306 8.8E-85 T 06-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 BWK49_RS18490 5c65246d06f4e78fe402822ad0a856ea 319 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 50 57 - T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 BWK49_RS18490 5c65246d06f4e78fe402822ad0a856ea 319 PRINTS PR00101 Aspartate carbamoyltransferase signature 264 269 5.4E-32 T 06-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 BWK49_RS18490 5c65246d06f4e78fe402822ad0a856ea 319 PRINTS PR00101 Aspartate carbamoyltransferase signature 139 156 5.4E-32 T 06-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 BWK49_RS18490 5c65246d06f4e78fe402822ad0a856ea 319 PRINTS PR00101 Aspartate carbamoyltransferase signature 40 62 5.4E-32 T 06-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 BWK49_RS18490 5c65246d06f4e78fe402822ad0a856ea 319 PRINTS PR00101 Aspartate carbamoyltransferase signature 288 302 5.4E-32 T 06-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 BWK49_RS18490 5c65246d06f4e78fe402822ad0a856ea 319 PRINTS PR00101 Aspartate carbamoyltransferase signature 223 232 5.4E-32 T 06-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 BWK49_RS18490 5c65246d06f4e78fe402822ad0a856ea 319 PRINTS PR00101 Aspartate carbamoyltransferase signature 78 87 5.4E-32 T 06-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 BWK49_RS18490 5c65246d06f4e78fe402822ad0a856ea 319 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 3 152 4.0E-36 T 06-07-2017 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 BWK49_RS18490 5c65246d06f4e78fe402822ad0a856ea 319 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 2 309 38.838 T 06-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 BWK49_RS18490 5c65246d06f4e78fe402822ad0a856ea 319 Gene3D G3DSA:3.40.50.1370 2 148 2.5E-47 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 BWK49_RS18490 5c65246d06f4e78fe402822ad0a856ea 319 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 140 151 6.3E-19 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 BWK49_RS18490 5c65246d06f4e78fe402822ad0a856ea 319 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 272 295 6.3E-19 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 BWK49_RS18490 5c65246d06f4e78fe402822ad0a856ea 319 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 260 269 6.3E-19 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 BWK49_RS18490 5c65246d06f4e78fe402822ad0a856ea 319 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 50 69 6.3E-19 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 BWK49_RS24015 771c10aa1e5290f262d0c603085f5950 124 Pfam PF00416 Ribosomal protein S13/S18 3 109 1.2E-35 T 06-07-2017 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 BWK49_RS24015 771c10aa1e5290f262d0c603085f5950 124 ProSitePatterns PS00646 Ribosomal protein S13 signature. 88 101 - T 06-07-2017 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 BWK49_RS24015 771c10aa1e5290f262d0c603085f5950 124 PIRSF PIRSF002134 1 124 4.0E-45 T 06-07-2017 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 BWK49_RS24015 771c10aa1e5290f262d0c603085f5950 124 Gene3D G3DSA:4.10.910.10 73 122 4.1E-27 T 06-07-2017 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 BWK49_RS24015 771c10aa1e5290f262d0c603085f5950 124 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 115 1.1E-52 T 06-07-2017 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS24015 771c10aa1e5290f262d0c603085f5950 124 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 120 28.18 T 06-07-2017 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 BWK49_RS24015 771c10aa1e5290f262d0c603085f5950 124 SUPERFAMILY SSF46946 2 121 2.22E-46 T 06-07-2017 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 BWK49_RS24015 771c10aa1e5290f262d0c603085f5950 124 Gene3D G3DSA:1.10.8.50 1 72 1.1E-30 T 06-07-2017 BWK49_RS01010 efc19303ca70e805d55fbce6d83d647d 207 Gene3D G3DSA:1.10.287.990 21 84 2.5E-21 T 06-07-2017 BWK49_RS01010 efc19303ca70e805d55fbce6d83d647d 207 PRINTS PR01703 Manganese superoxide dismutase signature 7 18 1.6E-20 T 06-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 BWK49_RS01010 efc19303ca70e805d55fbce6d83d647d 207 PRINTS PR01703 Manganese superoxide dismutase signature 67 80 1.6E-20 T 06-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 BWK49_RS01010 efc19303ca70e805d55fbce6d83d647d 207 PRINTS PR01703 Manganese superoxide dismutase signature 120 128 1.6E-20 T 06-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 BWK49_RS01010 efc19303ca70e805d55fbce6d83d647d 207 PRINTS PR01703 Manganese superoxide dismutase signature 158 170 1.6E-20 T 06-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 BWK49_RS01010 efc19303ca70e805d55fbce6d83d647d 207 PRINTS PR01703 Manganese superoxide dismutase signature 28 41 1.6E-20 T 06-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 BWK49_RS01010 efc19303ca70e805d55fbce6d83d647d 207 PIRSF PIRSF000349 1 203 1.0E-74 T 06-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 BWK49_RS01010 efc19303ca70e805d55fbce6d83d647d 207 SUPERFAMILY SSF54719 84 198 9.04E-44 T 06-07-2017 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 BWK49_RS01010 efc19303ca70e805d55fbce6d83d647d 207 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 91 193 3.7E-35 T 06-07-2017 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 BWK49_RS01010 efc19303ca70e805d55fbce6d83d647d 207 SUPERFAMILY SSF46609 3 88 4.84E-29 T 06-07-2017 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 BWK49_RS01010 efc19303ca70e805d55fbce6d83d647d 207 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 160 167 - T 06-07-2017 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 BWK49_RS01010 efc19303ca70e805d55fbce6d83d647d 207 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 3 84 2.2E-30 T 06-07-2017 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 BWK49_RS03370 ab644f1f9166f83a2e8d5b640d3a9251 252 SUPERFAMILY SSF52096 6 244 5.13E-57 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS03370 ab644f1f9166f83a2e8d5b640d3a9251 252 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 209 3.8E-38 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 BWK49_RS03370 ab644f1f9166f83a2e8d5b640d3a9251 252 Gene3D G3DSA:3.90.226.10 6 228 1.3E-57 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS18115 b97f13e2a6fbfd3e7d1d6290c5084dd9 568 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 260 314 - T 06-07-2017 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 BWK49_RS18115 b97f13e2a6fbfd3e7d1d6290c5084dd9 568 PRINTS PR01165 Cytochrome c oxidase subunit I signature 104 128 1.3E-96 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 BWK49_RS18115 b97f13e2a6fbfd3e7d1d6290c5084dd9 568 PRINTS PR01165 Cytochrome c oxidase subunit I signature 326 347 1.3E-96 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 BWK49_RS18115 b97f13e2a6fbfd3e7d1d6290c5084dd9 568 PRINTS PR01165 Cytochrome c oxidase subunit I signature 258 279 1.3E-96 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 BWK49_RS18115 b97f13e2a6fbfd3e7d1d6290c5084dd9 568 PRINTS PR01165 Cytochrome c oxidase subunit I signature 147 159 1.3E-96 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 BWK49_RS18115 b97f13e2a6fbfd3e7d1d6290c5084dd9 568 PRINTS PR01165 Cytochrome c oxidase subunit I signature 179 197 1.3E-96 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 BWK49_RS18115 b97f13e2a6fbfd3e7d1d6290c5084dd9 568 PRINTS PR01165 Cytochrome c oxidase subunit I signature 77 100 1.3E-96 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 BWK49_RS18115 b97f13e2a6fbfd3e7d1d6290c5084dd9 568 PRINTS PR01165 Cytochrome c oxidase subunit I signature 208 227 1.3E-96 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 BWK49_RS18115 b97f13e2a6fbfd3e7d1d6290c5084dd9 568 PRINTS PR01165 Cytochrome c oxidase subunit I signature 439 460 1.3E-96 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 BWK49_RS18115 b97f13e2a6fbfd3e7d1d6290c5084dd9 568 PRINTS PR01165 Cytochrome c oxidase subunit I signature 304 319 1.3E-96 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 BWK49_RS18115 b97f13e2a6fbfd3e7d1d6290c5084dd9 568 PRINTS PR01165 Cytochrome c oxidase subunit I signature 389 408 1.3E-96 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 BWK49_RS18115 b97f13e2a6fbfd3e7d1d6290c5084dd9 568 PRINTS PR01165 Cytochrome c oxidase subunit I signature 237 258 1.3E-96 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 BWK49_RS18115 b97f13e2a6fbfd3e7d1d6290c5084dd9 568 PRINTS PR01165 Cytochrome c oxidase subunit I signature 361 379 1.3E-96 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 BWK49_RS18115 b97f13e2a6fbfd3e7d1d6290c5084dd9 568 PRINTS PR01165 Cytochrome c oxidase subunit I signature 30 55 1.3E-96 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 BWK49_RS18115 b97f13e2a6fbfd3e7d1d6290c5084dd9 568 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 40 483 8.5E-148 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 BWK49_RS18115 b97f13e2a6fbfd3e7d1d6290c5084dd9 568 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 32 535 5.1E-212 T 06-07-2017 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005507|GO:0005886|GO:0006810|GO:0022900|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 BWK49_RS18115 b97f13e2a6fbfd3e7d1d6290c5084dd9 568 SUPERFAMILY SSF81442 27 538 9.42E-176 T 06-07-2017 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 BWK49_RS18115 b97f13e2a6fbfd3e7d1d6290c5084dd9 568 Gene3D G3DSA:1.20.210.10 24 548 1.7E-192 T 06-07-2017 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 BWK49_RS16385 db97ce68481d85bc24300ade5ded2cf6 471 SMART SM00304 185 237 2.7E-11 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 BWK49_RS16385 db97ce68481d85bc24300ade5ded2cf6 471 Pfam PF00672 HAMP domain 166 233 2.7E-16 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 BWK49_RS16385 db97ce68481d85bc24300ade5ded2cf6 471 SUPERFAMILY SSF55874 292 455 2.23E-38 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS16385 db97ce68481d85bc24300ade5ded2cf6 471 SMART SM00388 238 302 4.2E-11 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 BWK49_RS16385 db97ce68481d85bc24300ade5ded2cf6 471 SUPERFAMILY SSF158472 185 233 1.2E-9 T 06-07-2017 BWK49_RS16385 db97ce68481d85bc24300ade5ded2cf6 471 SMART SM00387 346 455 6.7E-31 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS16385 db97ce68481d85bc24300ade5ded2cf6 471 SUPERFAMILY SSF47384 221 300 3.53E-13 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 BWK49_RS16385 db97ce68481d85bc24300ade5ded2cf6 471 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 347 453 7.3E-22 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS16385 db97ce68481d85bc24300ade5ded2cf6 471 PRINTS PR00344 Bacterial sensor protein C-terminal signature 383 397 5.4E-17 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 BWK49_RS16385 db97ce68481d85bc24300ade5ded2cf6 471 PRINTS PR00344 Bacterial sensor protein C-terminal signature 415 433 5.4E-17 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 BWK49_RS16385 db97ce68481d85bc24300ade5ded2cf6 471 PRINTS PR00344 Bacterial sensor protein C-terminal signature 439 452 5.4E-17 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 BWK49_RS16385 db97ce68481d85bc24300ade5ded2cf6 471 PRINTS PR00344 Bacterial sensor protein C-terminal signature 401 411 5.4E-17 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 BWK49_RS16385 db97ce68481d85bc24300ade5ded2cf6 471 Gene3D G3DSA:3.30.565.10 304 454 9.7E-41 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS16385 db97ce68481d85bc24300ade5ded2cf6 471 Pfam PF00512 His Kinase A (phospho-acceptor) domain 239 301 4.6E-11 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 BWK49_RS16385 db97ce68481d85bc24300ade5ded2cf6 471 Gene3D G3DSA:1.10.287.130 228 295 3.9E-13 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 BWK49_RS18035 c82be66029f39c74f9f79a22d6abb992 492 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 1.8E-17 T 06-07-2017 BWK49_RS18035 c82be66029f39c74f9f79a22d6abb992 492 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 181 199 1.8E-17 T 06-07-2017 BWK49_RS18035 c82be66029f39c74f9f79a22d6abb992 492 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 266 282 1.8E-17 T 06-07-2017 BWK49_RS18035 c82be66029f39c74f9f79a22d6abb992 492 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 142 160 1.8E-17 T 06-07-2017 BWK49_RS18035 c82be66029f39c74f9f79a22d6abb992 492 Gene3D G3DSA:3.30.390.30 353 471 6.0E-26 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 BWK49_RS18035 c82be66029f39c74f9f79a22d6abb992 492 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 321 2.2E-44 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS18035 c82be66029f39c74f9f79a22d6abb992 492 SUPERFAMILY SSF55424 360 471 5.84E-25 T 06-07-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 BWK49_RS18035 c82be66029f39c74f9f79a22d6abb992 492 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 40 55 3.1E-47 T 06-07-2017 BWK49_RS18035 c82be66029f39c74f9f79a22d6abb992 492 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 311 318 3.1E-47 T 06-07-2017 BWK49_RS18035 c82be66029f39c74f9f79a22d6abb992 492 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 267 281 3.1E-47 T 06-07-2017 BWK49_RS18035 c82be66029f39c74f9f79a22d6abb992 492 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 8 30 3.1E-47 T 06-07-2017 BWK49_RS18035 c82be66029f39c74f9f79a22d6abb992 492 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 356 377 3.1E-47 T 06-07-2017 BWK49_RS18035 c82be66029f39c74f9f79a22d6abb992 492 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 423 438 3.1E-47 T 06-07-2017 BWK49_RS18035 c82be66029f39c74f9f79a22d6abb992 492 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 181 206 3.1E-47 T 06-07-2017 BWK49_RS18035 c82be66029f39c74f9f79a22d6abb992 492 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 445 465 3.1E-47 T 06-07-2017 BWK49_RS18035 c82be66029f39c74f9f79a22d6abb992 492 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 145 154 3.1E-47 T 06-07-2017 BWK49_RS18035 c82be66029f39c74f9f79a22d6abb992 492 SUPERFAMILY SSF51905 100 345 1.78E-39 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS18035 c82be66029f39c74f9f79a22d6abb992 492 SUPERFAMILY SSF51905 1 63 1.78E-39 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS18035 c82be66029f39c74f9f79a22d6abb992 492 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 361 466 2.7E-22 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 BWK49_RS18035 c82be66029f39c74f9f79a22d6abb992 492 Gene3D G3DSA:3.50.50.60 6 152 9.6E-29 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS18035 c82be66029f39c74f9f79a22d6abb992 492 Gene3D G3DSA:3.50.50.60 153 339 1.4E-34 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS18035 c82be66029f39c74f9f79a22d6abb992 492 PIRSF PIRSF000350 1 467 7.7E-68 T 06-07-2017 BWK49_RS06235 a9761dad5f5e185a195ebca0eb9f41b1 126 TIGRFAM TIGR02425 decarb_PcaC: 4-carboxymuconolactone decarboxylase 3 123 9.9E-47 T 06-07-2017 IPR012788 4-carboxymuconolactone decarboxylase KEGG: 00362+4.1.1.44 BWK49_RS06235 a9761dad5f5e185a195ebca0eb9f41b1 126 SUPERFAMILY SSF69118 4 122 3.53E-36 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 BWK49_RS06235 a9761dad5f5e185a195ebca0eb9f41b1 126 Gene3D G3DSA:1.20.1290.10 4 123 6.8E-33 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 BWK49_RS06235 a9761dad5f5e185a195ebca0eb9f41b1 126 Pfam PF02627 Carboxymuconolactone decarboxylase family 36 118 4.5E-24 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 BWK49_RS07170 58eaf84506beeea8f7b1950bae86928a 432 PRINTS PR00385 P450 superfamily signature 259 276 1.7E-13 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS07170 58eaf84506beeea8f7b1950bae86928a 432 PRINTS PR00385 P450 superfamily signature 372 381 1.7E-13 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS07170 58eaf84506beeea8f7b1950bae86928a 432 PRINTS PR00385 P450 superfamily signature 300 311 1.7E-13 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS07170 58eaf84506beeea8f7b1950bae86928a 432 PRINTS PR00385 P450 superfamily signature 381 392 1.7E-13 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS07170 58eaf84506beeea8f7b1950bae86928a 432 Pfam PF00067 Cytochrome P450 7 414 9.0E-76 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS07170 58eaf84506beeea8f7b1950bae86928a 432 Gene3D G3DSA:1.10.630.10 6 430 5.8E-100 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS07170 58eaf84506beeea8f7b1950bae86928a 432 PRINTS PR00463 E-class P450 group I signature 268 294 4.6E-26 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS07170 58eaf84506beeea8f7b1950bae86928a 432 PRINTS PR00463 E-class P450 group I signature 248 265 4.6E-26 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS07170 58eaf84506beeea8f7b1950bae86928a 432 PRINTS PR00463 E-class P450 group I signature 339 363 4.6E-26 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS07170 58eaf84506beeea8f7b1950bae86928a 432 PRINTS PR00463 E-class P450 group I signature 371 381 4.6E-26 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS07170 58eaf84506beeea8f7b1950bae86928a 432 PRINTS PR00463 E-class P450 group I signature 299 317 4.6E-26 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS07170 58eaf84506beeea8f7b1950bae86928a 432 PRINTS PR00463 E-class P450 group I signature 381 404 4.6E-26 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS07170 58eaf84506beeea8f7b1950bae86928a 432 PRINTS PR00463 E-class P450 group I signature 33 52 4.6E-26 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS07170 58eaf84506beeea8f7b1950bae86928a 432 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 374 383 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 BWK49_RS07170 58eaf84506beeea8f7b1950bae86928a 432 SUPERFAMILY SSF48264 6 431 2.88E-96 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS17515 229dc69949be4daf1f3b96ad45809556 290 Gene3D G3DSA:3.40.50.150 18 192 2.2E-21 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS17515 229dc69949be4daf1f3b96ad45809556 290 PIRSF PIRSF028177 5 283 5.2E-54 T 06-07-2017 IPR016874 Tetracenomycin polyketide synthesis O-methyltransferase TcmP GO:0017000|GO:1901106 BWK49_RS17515 229dc69949be4daf1f3b96ad45809556 290 SUPERFAMILY SSF53335 17 241 5.46E-45 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS17515 229dc69949be4daf1f3b96ad45809556 290 Pfam PF04072 Leucine carboxyl methyltransferase 23 178 6.9E-13 T 06-07-2017 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 BWK49_RS23455 e3f552148841a8570b39198995c877b1 310 SUPERFAMILY SSF88946 10 88 3.34E-14 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS23455 e3f552148841a8570b39198995c877b1 310 Pfam PF04542 Sigma-70 region 2 10 76 1.4E-14 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS23455 e3f552148841a8570b39198995c877b1 310 SUPERFAMILY SSF88659 113 168 1.23E-10 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS23455 e3f552148841a8570b39198995c877b1 310 Gene3D G3DSA:1.10.10.10 114 170 3.9E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS23455 e3f552148841a8570b39198995c877b1 310 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 10 167 1.8E-15 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS23455 e3f552148841a8570b39198995c877b1 310 Gene3D G3DSA:1.10.1740.10 10 78 4.5E-14 T 06-07-2017 BWK49_RS23455 e3f552148841a8570b39198995c877b1 310 Gene3D G3DSA:3.10.450.50 179 300 2.3E-12 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS23455 e3f552148841a8570b39198995c877b1 310 Pfam PF08281 Sigma-70, region 4 119 167 3.0E-12 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS23455 e3f552148841a8570b39198995c877b1 310 SUPERFAMILY SSF54427 174 300 1.56E-17 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS23455 e3f552148841a8570b39198995c877b1 310 Pfam PF12680 SnoaL-like domain 185 290 2.6E-7 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain BWK49_RS12075 ca2d8594332ed5c0cfb4ce5efdbd1fc6 398 Gene3D G3DSA:3.90.1150.10 248 394 1.9E-45 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 BWK49_RS12075 ca2d8594332ed5c0cfb4ce5efdbd1fc6 398 Gene3D G3DSA:3.40.640.10 42 247 5.3E-42 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 BWK49_RS12075 ca2d8594332ed5c0cfb4ce5efdbd1fc6 398 SUPERFAMILY SSF53383 20 394 7.46E-75 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase BWK49_RS12075 ca2d8594332ed5c0cfb4ce5efdbd1fc6 398 Pfam PF00155 Aminotransferase class I and II 68 389 5.4E-28 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 BWK49_RS22315 1711ed144cd4d99aa79f0e4561a3ab19 385 Gene3D G3DSA:3.30.565.10 283 381 3.9E-10 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS22315 1711ed144cd4d99aa79f0e4561a3ab19 385 SUPERFAMILY SSF55874 281 379 1.31E-12 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS22315 1711ed144cd4d99aa79f0e4561a3ab19 385 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 289 379 1.5E-7 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS13820 7e7fbdfdc2162971e7d200fa3c9ad07d 161 SMART SM01116 78 149 6.1E-42 T 06-07-2017 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 BWK49_RS13820 7e7fbdfdc2162971e7d200fa3c9ad07d 161 Gene3D G3DSA:1.10.260.40 3 83 3.4E-29 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 BWK49_RS13820 7e7fbdfdc2162971e7d200fa3c9ad07d 161 SUPERFAMILY SSF55234 84 149 1.15E-26 T 06-07-2017 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 BWK49_RS13820 7e7fbdfdc2162971e7d200fa3c9ad07d 161 Pfam PF02560 Cyanate lyase C-terminal domain 82 148 2.5E-33 T 06-07-2017 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 BWK49_RS13820 7e7fbdfdc2162971e7d200fa3c9ad07d 161 PRINTS PR01693 Cyanase signature 38 55 2.7E-29 T 06-07-2017 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 BWK49_RS13820 7e7fbdfdc2162971e7d200fa3c9ad07d 161 PRINTS PR01693 Cyanase signature 18 33 2.7E-29 T 06-07-2017 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 BWK49_RS13820 7e7fbdfdc2162971e7d200fa3c9ad07d 161 PRINTS PR01693 Cyanase signature 135 145 2.7E-29 T 06-07-2017 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 BWK49_RS13820 7e7fbdfdc2162971e7d200fa3c9ad07d 161 PRINTS PR01693 Cyanase signature 86 100 2.7E-29 T 06-07-2017 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 BWK49_RS13820 7e7fbdfdc2162971e7d200fa3c9ad07d 161 PRINTS PR01693 Cyanase signature 104 120 2.7E-29 T 06-07-2017 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 BWK49_RS13820 7e7fbdfdc2162971e7d200fa3c9ad07d 161 PIRSF PIRSF001263 1 150 4.1E-49 T 06-07-2017 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 BWK49_RS13820 7e7fbdfdc2162971e7d200fa3c9ad07d 161 Hamap MF_00535 Cyanate hydratase [cynS]. 1 161 67.087 T 06-07-2017 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 BWK49_RS13820 7e7fbdfdc2162971e7d200fa3c9ad07d 161 Gene3D G3DSA:3.30.1160.10 85 148 1.4E-33 T 06-07-2017 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 BWK49_RS13820 7e7fbdfdc2162971e7d200fa3c9ad07d 161 TIGRFAM TIGR00673 cynS: cyanase 8 147 8.2E-48 T 06-07-2017 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 BWK49_RS13820 7e7fbdfdc2162971e7d200fa3c9ad07d 161 SUPERFAMILY SSF47413 6 80 9.93E-20 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 BWK49_RS22505 bf7c6331fbd17721c9bba9dd366bbd72 237 Pfam PF00881 Nitroreductase family 3 167 1.4E-18 T 06-07-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 BWK49_RS22505 bf7c6331fbd17721c9bba9dd366bbd72 237 Gene3D G3DSA:3.40.109.10 3 48 6.4E-27 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 BWK49_RS22505 bf7c6331fbd17721c9bba9dd366bbd72 237 Gene3D G3DSA:3.40.109.10 89 197 6.4E-27 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 BWK49_RS22505 bf7c6331fbd17721c9bba9dd366bbd72 237 SUPERFAMILY SSF55469 2 48 2.49E-29 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 BWK49_RS22505 bf7c6331fbd17721c9bba9dd366bbd72 237 SUPERFAMILY SSF55469 89 194 2.49E-29 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 BWK49_RS19000 02fe6c20b02e1ee3761493db86391c6a 408 PRINTS PR00149 Fumarate lyase superfamily signature 277 293 1.4E-12 T 06-07-2017 IPR000362 Fumarate lyase family BWK49_RS19000 02fe6c20b02e1ee3761493db86391c6a 408 PRINTS PR00149 Fumarate lyase superfamily signature 93 111 1.4E-12 T 06-07-2017 IPR000362 Fumarate lyase family BWK49_RS19000 02fe6c20b02e1ee3761493db86391c6a 408 PRINTS PR00149 Fumarate lyase superfamily signature 138 156 1.4E-12 T 06-07-2017 IPR000362 Fumarate lyase family BWK49_RS19000 02fe6c20b02e1ee3761493db86391c6a 408 Pfam PF00206 Lyase 86 297 3.7E-26 T 06-07-2017 IPR022761 Fumarate lyase, N-terminal BWK49_RS19000 02fe6c20b02e1ee3761493db86391c6a 408 ProSitePatterns PS00163 Fumarate lyases signature. 277 286 - T 06-07-2017 IPR020557 Fumarate lyase, conserved site GO:0003824 BWK49_RS19000 02fe6c20b02e1ee3761493db86391c6a 408 Gene3D G3DSA:1.10.275.10 10 95 2.6E-12 T 06-07-2017 IPR024083 Fumarase/histidase, N-terminal BWK49_RS19000 02fe6c20b02e1ee3761493db86391c6a 408 Gene3D G3DSA:1.20.200.10 96 364 9.0E-70 T 06-07-2017 BWK49_RS19000 02fe6c20b02e1ee3761493db86391c6a 408 SUPERFAMILY SSF48557 14 364 6.44E-63 T 06-07-2017 IPR008948 L-Aspartase-like GO:0003824 BWK49_RS05775 0a14f0f17d6f1958d559a6183a73c8a8 274 Gene3D G3DSA:3.40.50.720 5 243 7.4E-52 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS05775 0a14f0f17d6f1958d559a6183a73c8a8 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 187 204 1.9E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05775 0a14f0f17d6f1958d559a6183a73c8a8 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 91 102 1.9E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05775 0a14f0f17d6f1958d559a6183a73c8a8 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 1.9E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05775 0a14f0f17d6f1958d559a6183a73c8a8 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 185 1.9E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05775 0a14f0f17d6f1958d559a6183a73c8a8 274 SUPERFAMILY SSF51735 6 244 7.04E-49 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS05775 0a14f0f17d6f1958d559a6183a73c8a8 274 Pfam PF00106 short chain dehydrogenase 10 207 1.4E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS23510 1328314251416b03edf6089b06514163 745 Pfam PF03971 Monomeric isocitrate dehydrogenase 7 740 0.0 T 06-07-2017 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 BWK49_RS23510 1328314251416b03edf6089b06514163 745 PIRSF PIRSF009407 1 744 0.0 T 06-07-2017 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 BWK49_RS23510 1328314251416b03edf6089b06514163 745 TIGRFAM TIGR00178 monomer_idh: isocitrate dehydrogenase, NADP-dependent 2 744 0.0 T 06-07-2017 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 BWK49_RS23510 1328314251416b03edf6089b06514163 745 SUPERFAMILY SSF53659 5 742 0.0 T 06-07-2017 BWK49_RS23510 1328314251416b03edf6089b06514163 745 Gene3D G3DSA:3.40.718.10 541 648 1.1E-28 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 BWK49_RS23510 1328314251416b03edf6089b06514163 745 Gene3D G3DSA:3.40.718.10 341 364 1.1E-28 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 BWK49_RS23510 1328314251416b03edf6089b06514163 745 Gene3D G3DSA:3.40.718.10 148 286 1.1E-28 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 BWK49_RS05360 4681b25ba7b428f09a7bcc85a9193406 258 Gene3D G3DSA:3.90.226.10 6 256 1.1E-82 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS05360 4681b25ba7b428f09a7bcc85a9193406 258 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 257 5.0E-70 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 BWK49_RS05360 4681b25ba7b428f09a7bcc85a9193406 258 SUPERFAMILY SSF52096 4 257 1.23E-79 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS15920 f0b70f72863eb43efb49c24750d63893 459 Pfam PF07282 Putative transposase DNA-binding domain 344 407 4.4E-15 T 06-07-2017 IPR010095 Transposase IS605, OrfB, C-terminal BWK49_RS15920 f0b70f72863eb43efb49c24750d63893 459 Pfam PF01385 Probable transposase 205 320 1.0E-29 T 06-07-2017 IPR001959 Probable transposase, IS891/IS1136/IS1341 BWK49_RS15920 f0b70f72863eb43efb49c24750d63893 459 Pfam PF12323 Helix-turn-helix domain 14 48 2.4E-7 T 06-07-2017 IPR021027 Transposase, putative, helix-turn-helix domain BWK49_RS18260 3afd252012d4771b0495e92f1af6bb12 411 Gene3D G3DSA:3.40.50.1270 189 391 9.6E-77 T 06-07-2017 IPR015901 Phosphoglycerate kinase, C-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 BWK49_RS18260 3afd252012d4771b0495e92f1af6bb12 411 Pfam PF00162 Phosphoglycerate kinase 14 393 1.8E-135 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 BWK49_RS18260 3afd252012d4771b0495e92f1af6bb12 411 Gene3D G3DSA:3.40.50.1260 9 188 6.1E-59 T 06-07-2017 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 BWK49_RS18260 3afd252012d4771b0495e92f1af6bb12 411 PRINTS PR00477 Phosphoglycerate kinase family signature 13 29 1.7E-74 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 BWK49_RS18260 3afd252012d4771b0495e92f1af6bb12 411 PRINTS PR00477 Phosphoglycerate kinase family signature 147 169 1.7E-74 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 BWK49_RS18260 3afd252012d4771b0495e92f1af6bb12 411 PRINTS PR00477 Phosphoglycerate kinase family signature 177 199 1.7E-74 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 BWK49_RS18260 3afd252012d4771b0495e92f1af6bb12 411 PRINTS PR00477 Phosphoglycerate kinase family signature 319 344 1.7E-74 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 BWK49_RS18260 3afd252012d4771b0495e92f1af6bb12 411 PRINTS PR00477 Phosphoglycerate kinase family signature 34 56 1.7E-74 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 BWK49_RS18260 3afd252012d4771b0495e92f1af6bb12 411 PRINTS PR00477 Phosphoglycerate kinase family signature 112 127 1.7E-74 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 BWK49_RS18260 3afd252012d4771b0495e92f1af6bb12 411 PRINTS PR00477 Phosphoglycerate kinase family signature 200 219 1.7E-74 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 BWK49_RS18260 3afd252012d4771b0495e92f1af6bb12 411 PRINTS PR00477 Phosphoglycerate kinase family signature 355 366 1.7E-74 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 BWK49_RS18260 3afd252012d4771b0495e92f1af6bb12 411 PRINTS PR00477 Phosphoglycerate kinase family signature 379 396 1.7E-74 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 BWK49_RS18260 3afd252012d4771b0495e92f1af6bb12 411 SUPERFAMILY SSF53748 9 402 6.36E-138 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 BWK49_RS18260 3afd252012d4771b0495e92f1af6bb12 411 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 18 28 - T 06-07-2017 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 BWK49_RS18260 3afd252012d4771b0495e92f1af6bb12 411 PIRSF PIRSF000724 2 408 3.2E-128 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 BWK49_RS18260 3afd252012d4771b0495e92f1af6bb12 411 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 8 403 39.21 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 BWK49_RS21435 894ce1c3a771e064c286162ea67b7798 321 Gene3D G3DSA:3.20.20.30 2 317 1.7E-71 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS21435 894ce1c3a771e064c286162ea67b7798 321 Pfam PF00296 Luciferase-like monooxygenase 3 290 1.5E-56 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS21435 894ce1c3a771e064c286162ea67b7798 321 SUPERFAMILY SSF51679 1 317 8.51E-69 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS21435 894ce1c3a771e064c286162ea67b7798 321 TIGRFAM TIGR03557 F420_G6P_family: F420-dependent oxidoreductase, G6PDH family 4 317 6.3E-154 T 06-07-2017 IPR019945 F420-dependent glucose-6-phosphate dehydrogenase-related BWK49_RS06185 d7376ae61db7f72b88838572b7de4cdb 391 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 122 1.5E-15 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS06185 d7376ae61db7f72b88838572b7de4cdb 391 Gene3D G3DSA:1.10.540.10 5 124 3.0E-20 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS06185 d7376ae61db7f72b88838572b7de4cdb 391 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 129 141 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 BWK49_RS06185 d7376ae61db7f72b88838572b7de4cdb 391 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 235 386 1.1E-14 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS06185 d7376ae61db7f72b88838572b7de4cdb 391 SUPERFAMILY SSF47203 235 389 1.77E-15 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS06185 d7376ae61db7f72b88838572b7de4cdb 391 SUPERFAMILY SSF56645 3 248 3.53E-67 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS06185 d7376ae61db7f72b88838572b7de4cdb 391 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 127 223 7.8E-21 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 BWK49_RS06185 d7376ae61db7f72b88838572b7de4cdb 391 Gene3D G3DSA:1.20.140.10 224 390 5.4E-28 T 06-07-2017 BWK49_RS06185 d7376ae61db7f72b88838572b7de4cdb 391 Gene3D G3DSA:2.40.110.10 127 223 1.4E-36 T 06-07-2017 BWK49_RS16980 ca842e651a3ef9a1781a9ad1c391fee3 828 Pfam PF03484 tRNA synthetase B5 domain 416 480 6.3E-12 T 06-07-2017 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 BWK49_RS16980 ca842e651a3ef9a1781a9ad1c391fee3 828 SUPERFAMILY SSF56037 205 401 6.28E-61 T 06-07-2017 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 Reactome: R-HSA-379716 BWK49_RS16980 ca842e651a3ef9a1781a9ad1c391fee3 828 SMART SM00896 734 827 1.3E-40 T 06-07-2017 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 BWK49_RS16980 ca842e651a3ef9a1781a9ad1c391fee3 828 SUPERFAMILY SSF50249 49 197 3.18E-32 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS16980 ca842e651a3ef9a1781a9ad1c391fee3 828 Gene3D G3DSA:3.30.70.380 736 827 1.2E-28 T 06-07-2017 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 BWK49_RS16980 ca842e651a3ef9a1781a9ad1c391fee3 828 SMART SM00874 413 481 7.5E-16 T 06-07-2017 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 BWK49_RS16980 ca842e651a3ef9a1781a9ad1c391fee3 828 Gene3D G3DSA:3.30.56.10 1 43 7.9E-13 T 06-07-2017 BWK49_RS16980 ca842e651a3ef9a1781a9ad1c391fee3 828 Gene3D G3DSA:3.30.56.10 162 191 7.9E-13 T 06-07-2017 BWK49_RS16980 ca842e651a3ef9a1781a9ad1c391fee3 828 Gene3D G3DSA:2.40.50.140 47 161 3.4E-38 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS16980 ca842e651a3ef9a1781a9ad1c391fee3 828 SUPERFAMILY SSF54991 732 827 4.84E-26 T 06-07-2017 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 BWK49_RS16980 ca842e651a3ef9a1781a9ad1c391fee3 828 SMART SM00873 219 392 3.5E-74 T 06-07-2017 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 BWK49_RS16980 ca842e651a3ef9a1781a9ad1c391fee3 828 Gene3D G3DSA:3.30.930.10 497 723 3.1E-57 T 06-07-2017 BWK49_RS16980 ca842e651a3ef9a1781a9ad1c391fee3 828 Pfam PF03147 Ferredoxin-fold anticodon binding domain 734 827 2.2E-25 T 06-07-2017 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 BWK49_RS16980 ca842e651a3ef9a1781a9ad1c391fee3 828 SUPERFAMILY SSF46955 416 485 2.01E-13 T 06-07-2017 IPR009061 Putative DNA-binding domain BWK49_RS16980 ca842e651a3ef9a1781a9ad1c391fee3 828 Pfam PF01588 Putative tRNA binding domain 50 152 5.1E-19 T 06-07-2017 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 BWK49_RS16980 ca842e651a3ef9a1781a9ad1c391fee3 828 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 827 3.0E-162 T 06-07-2017 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 BWK49_RS16980 ca842e651a3ef9a1781a9ad1c391fee3 828 Pfam PF03483 B3/4 domain 221 392 5.2E-58 T 06-07-2017 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 BWK49_RS16980 ca842e651a3ef9a1781a9ad1c391fee3 828 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 821 39.279 T 06-07-2017 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 BWK49_RS16980 ca842e651a3ef9a1781a9ad1c391fee3 828 Gene3D G3DSA:3.30.56.20 415 485 1.2E-18 T 06-07-2017 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 BWK49_RS16980 ca842e651a3ef9a1781a9ad1c391fee3 828 Gene3D G3DSA:3.50.40.10 208 401 3.8E-69 T 06-07-2017 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 Reactome: R-HSA-379716 BWK49_RS16980 ca842e651a3ef9a1781a9ad1c391fee3 828 SUPERFAMILY SSF55681 477 593 1.64E-33 T 06-07-2017 BWK49_RS16980 ca842e651a3ef9a1781a9ad1c391fee3 828 SUPERFAMILY SSF55681 623 722 1.64E-33 T 06-07-2017 BWK49_RS09800 781219e361f7a98ed92eafae030492cd 691 Pfam PF09678 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) 396 645 5.3E-86 T 06-07-2017 IPR019108 Cytochrome c oxidase caa3-type, assembly factor CtaG-related BWK49_RS09800 781219e361f7a98ed92eafae030492cd 691 Pfam PF05425 Copper resistance protein D 244 344 6.1E-21 T 06-07-2017 IPR008457 Copper resistance protein D GO:0016021 BWK49_RS02440 bb00a0406d93dc6b0ec2b4c728418f33 353 Gene3D G3DSA:3.40.50.720 7 167 4.7E-26 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS02440 bb00a0406d93dc6b0ec2b4c728418f33 353 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 12 75 1.2E-5 T 06-07-2017 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 BWK49_RS02440 bb00a0406d93dc6b0ec2b4c728418f33 353 SUPERFAMILY SSF51735 5 145 1.27E-12 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS23610 8c2b7be9e73c606e07b14bd5e95b62da 1095 Gene3D G3DSA:3.20.20.140 59 274 2.6E-24 T 06-07-2017 BWK49_RS23610 8c2b7be9e73c606e07b14bd5e95b62da 1095 Hamap MF_01902 Error-prone DNA polymerase [dnaE2]. 58 1095 12.904 T 06-07-2017 IPR023073 DNA polymerase, error-prone GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 BWK49_RS23610 8c2b7be9e73c606e07b14bd5e95b62da 1095 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 350 765 1.6E-142 T 06-07-2017 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 BWK49_RS23610 8c2b7be9e73c606e07b14bd5e95b62da 1095 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 59 930 2.5E-194 T 06-07-2017 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 BWK49_RS23610 8c2b7be9e73c606e07b14bd5e95b62da 1095 SUPERFAMILY SSF89550 59 267 1.44E-22 T 06-07-2017 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 BWK49_RS23610 8c2b7be9e73c606e07b14bd5e95b62da 1095 Pfam PF14579 Helix-hairpin-helix motif 841 928 8.5E-26 T 06-07-2017 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 BWK49_RS23610 8c2b7be9e73c606e07b14bd5e95b62da 1095 Pfam PF02811 PHP domain 60 231 6.7E-30 T 06-07-2017 IPR004013 PHP domain GO:0003824 BWK49_RS23610 8c2b7be9e73c606e07b14bd5e95b62da 1095 Gene3D G3DSA:2.40.50.140 1002 1070 1.0E-4 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS23610 8c2b7be9e73c606e07b14bd5e95b62da 1095 Gene3D G3DSA:1.10.150.280 869 914 1.5E-4 T 06-07-2017 BWK49_RS23610 8c2b7be9e73c606e07b14bd5e95b62da 1095 SMART SM00481 59 126 1.7E-24 T 06-07-2017 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 BWK49_RS00030 a8d67301a7632b8f2139a3bf67ab15f4 838 SMART SM00434 19 477 4.7E-275 T 06-07-2017 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 BWK49_RS00030 a8d67301a7632b8f2139a3bf67ab15f4 838 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 623 667 1.4E-9 T 06-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 BWK49_RS00030 a8d67301a7632b8f2139a3bf67ab15f4 838 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 723 770 1.4E-11 T 06-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 BWK49_RS00030 a8d67301a7632b8f2139a3bf67ab15f4 838 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 566 609 4.0E-9 T 06-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 BWK49_RS00030 a8d67301a7632b8f2139a3bf67ab15f4 838 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 670 718 6.9E-12 T 06-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 BWK49_RS00030 a8d67301a7632b8f2139a3bf67ab15f4 838 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 516 563 8.0E-12 T 06-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 BWK49_RS00030 a8d67301a7632b8f2139a3bf67ab15f4 838 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 774 816 1.7E-8 T 06-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 BWK49_RS00030 a8d67301a7632b8f2139a3bf67ab15f4 838 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 16 819 0.0 T 06-07-2017 BWK49_RS00030 a8d67301a7632b8f2139a3bf67ab15f4 838 SUPERFAMILY SSF101904 511 832 5.23E-103 T 06-07-2017 BWK49_RS00030 a8d67301a7632b8f2139a3bf67ab15f4 838 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 11 821 23.72 T 06-07-2017 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 BWK49_RS00030 a8d67301a7632b8f2139a3bf67ab15f4 838 Gene3D G3DSA:2.120.10.90 508 818 1.1E-118 T 06-07-2017 BWK49_RS00030 a8d67301a7632b8f2139a3bf67ab15f4 838 Gene3D G3DSA:3.90.199.10 32 289 1.4E-114 T 06-07-2017 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 BWK49_RS00030 a8d67301a7632b8f2139a3bf67ab15f4 838 SUPERFAMILY SSF56719 12 501 5.23E-169 T 06-07-2017 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 BWK49_RS00030 a8d67301a7632b8f2139a3bf67ab15f4 838 Gene3D G3DSA:1.10.268.10 376 475 2.8E-29 T 06-07-2017 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 BWK49_RS00030 a8d67301a7632b8f2139a3bf67ab15f4 838 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 40 483 3.9E-147 T 06-07-2017 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 BWK49_RS00855 32a6d195a6e25197fb8803837a7852b5 104 Gene3D G3DSA:1.10.287.1060 2 95 2.9E-4 T 06-07-2017 BWK49_RS00855 32a6d195a6e25197fb8803837a7852b5 104 Pfam PF06013 Proteins of 100 residues with WXG 3 88 2.1E-11 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like BWK49_RS00855 32a6d195a6e25197fb8803837a7852b5 104 SUPERFAMILY SSF140453 2 96 2.09E-8 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like BWK49_RS11890 5ca123c8207d62da6878628fd6e47227 390 Pfam PF02515 CoA-transferase family III 4 366 6.6E-74 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 BWK49_RS11890 5ca123c8207d62da6878628fd6e47227 390 Gene3D G3DSA:3.40.50.10540 298 390 4.7E-72 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS11890 5ca123c8207d62da6878628fd6e47227 390 Gene3D G3DSA:3.40.50.10540 2 213 4.7E-72 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS11890 5ca123c8207d62da6878628fd6e47227 390 Gene3D G3DSA:3.30.1540.10 222 297 7.8E-13 T 06-07-2017 BWK49_RS11890 5ca123c8207d62da6878628fd6e47227 390 SUPERFAMILY SSF89796 2 390 2.88E-83 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS24395 7ce863889e4465a498ba451527b134f2 275 Gene3D G3DSA:3.30.540.10 5 149 4.7E-44 T 06-07-2017 BWK49_RS24395 7ce863889e4465a498ba451527b134f2 275 Pfam PF00459 Inositol monophosphatase family 7 261 1.3E-56 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 BWK49_RS24395 7ce863889e4465a498ba451527b134f2 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 37 57 5.8E-40 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 BWK49_RS24395 7ce863889e4465a498ba451527b134f2 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 81 97 5.8E-40 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 BWK49_RS24395 7ce863889e4465a498ba451527b134f2 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 59 75 5.8E-40 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 BWK49_RS24395 7ce863889e4465a498ba451527b134f2 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 211 235 5.8E-40 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 BWK49_RS24395 7ce863889e4465a498ba451527b134f2 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 130 153 5.8E-40 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 BWK49_RS24395 7ce863889e4465a498ba451527b134f2 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 180 201 5.8E-40 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 BWK49_RS24395 7ce863889e4465a498ba451527b134f2 275 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 81 94 - T 06-07-2017 IPR020583 Inositol monophosphatase, metal-binding site BWK49_RS24395 7ce863889e4465a498ba451527b134f2 275 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 214 228 - T 06-07-2017 IPR020550 Inositol monophosphatase, conserved site GO:0046854 BWK49_RS24395 7ce863889e4465a498ba451527b134f2 275 Gene3D G3DSA:3.40.190.80 150 262 1.6E-28 T 06-07-2017 BWK49_RS24395 7ce863889e4465a498ba451527b134f2 275 SUPERFAMILY SSF56655 4 262 2.23E-70 T 06-07-2017 BWK49_RS06865 55ec75fa941ec90839063bcb949f7555 368 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 49 367 1.1E-103 T 06-07-2017 IPR005673 ABC transporter, phosphate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 BWK49_RS06865 55ec75fa941ec90839063bcb949f7555 368 PIRSF PIRSF002756 5 368 2.0E-106 T 06-07-2017 IPR005673 ABC transporter, phosphate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 BWK49_RS06865 55ec75fa941ec90839063bcb949f7555 368 SUPERFAMILY SSF53850 49 367 3.26E-79 T 06-07-2017 BWK49_RS06865 55ec75fa941ec90839063bcb949f7555 368 Gene3D G3DSA:3.40.190.10 48 200 1.8E-42 T 06-07-2017 BWK49_RS06865 55ec75fa941ec90839063bcb949f7555 368 Gene3D G3DSA:3.40.190.10 228 366 3.1E-18 T 06-07-2017 BWK49_RS06865 55ec75fa941ec90839063bcb949f7555 368 Pfam PF12849 PBP superfamily domain 46 334 5.7E-52 T 06-07-2017 IPR024370 PBP domain BWK49_RS25300 e1a3abcf1d215c80b0b3d7ff459cdf04 173 Pfam PF13452 N-terminal half of MaoC dehydratase 10 140 3.1E-28 T 06-07-2017 BWK49_RS25300 e1a3abcf1d215c80b0b3d7ff459cdf04 173 Hamap MF_00799 UPF0336 protein . 1 151 33.139 T 06-07-2017 IPR016709 Uncharacterised protein family UPF0336 BWK49_RS25300 e1a3abcf1d215c80b0b3d7ff459cdf04 173 PIRSF PIRSF018072 1 153 4.1E-58 T 06-07-2017 IPR016709 Uncharacterised protein family UPF0336 BWK49_RS25300 e1a3abcf1d215c80b0b3d7ff459cdf04 173 SUPERFAMILY SSF54637 10 147 1.35E-33 T 06-07-2017 IPR029069 HotDog domain BWK49_RS25300 e1a3abcf1d215c80b0b3d7ff459cdf04 173 Gene3D G3DSA:3.10.129.10 12 146 1.3E-22 T 06-07-2017 IPR029069 HotDog domain BWK49_RS01905 2551e4ca89a9d4486561f3b50ff68693 132 SUPERFAMILY SSF55718 2 126 2.59E-26 T 06-07-2017 IPR003033 SCP2 sterol-binding domain BWK49_RS01905 2551e4ca89a9d4486561f3b50ff68693 132 Gene3D G3DSA:3.30.1050.10 6 116 1.8E-13 T 06-07-2017 IPR003033 SCP2 sterol-binding domain BWK49_RS01905 2551e4ca89a9d4486561f3b50ff68693 132 Pfam PF02036 SCP-2 sterol transfer family 22 110 3.0E-9 T 06-07-2017 IPR003033 SCP2 sterol-binding domain BWK49_RS24480 fedf99c3966e83edf6bd1a604087ab4f 251 ProSitePatterns PS00729 AP endonucleases family 2 signature 1. 56 64 - T 06-07-2017 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 BWK49_RS24480 fedf99c3966e83edf6bd1a604087ab4f 251 ProSitePatterns PS00730 AP endonucleases family 2 signature 2. 157 164 - T 06-07-2017 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 BWK49_RS24480 fedf99c3966e83edf6bd1a604087ab4f 251 SUPERFAMILY SSF51658 3 246 1.96E-58 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain BWK49_RS24480 fedf99c3966e83edf6bd1a604087ab4f 251 SMART SM00518 2 249 8.9E-68 T 06-07-2017 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 BWK49_RS24480 fedf99c3966e83edf6bd1a604087ab4f 251 Gene3D G3DSA:3.20.20.150 2 247 1.2E-62 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain BWK49_RS24480 fedf99c3966e83edf6bd1a604087ab4f 251 ProSitePatterns PS00731 AP endonucleases family 2 signature 3. 189 205 - T 06-07-2017 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 BWK49_RS24480 fedf99c3966e83edf6bd1a604087ab4f 251 Pfam PF01261 Xylose isomerase-like TIM barrel 13 213 3.5E-31 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain BWK49_RS11125 e68a7550d94f7ba40fe86e28a001ee96 386 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 250 381 1.5E-21 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS11125 e68a7550d94f7ba40fe86e28a001ee96 386 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 118 3.4E-13 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS11125 e68a7550d94f7ba40fe86e28a001ee96 386 SUPERFAMILY SSF47203 250 385 6.12E-19 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS11125 e68a7550d94f7ba40fe86e28a001ee96 386 Gene3D G3DSA:2.40.110.10 122 216 1.0E-30 T 06-07-2017 BWK49_RS11125 e68a7550d94f7ba40fe86e28a001ee96 386 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 207 2.2E-21 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 BWK49_RS11125 e68a7550d94f7ba40fe86e28a001ee96 386 SUPERFAMILY SSF56645 2 238 1.31E-57 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS11125 e68a7550d94f7ba40fe86e28a001ee96 386 Gene3D G3DSA:1.10.540.10 1 119 1.1E-14 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS11125 e68a7550d94f7ba40fe86e28a001ee96 386 Gene3D G3DSA:1.20.140.10 217 386 1.1E-25 T 06-07-2017 BWK49_RS28045 a31c278b68e2f1548900f5295727e2e2 256 Gene3D G3DSA:3.40.50.720 2 254 5.8E-74 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS28045 a31c278b68e2f1548900f5295727e2e2 256 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 148 176 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS28045 a31c278b68e2f1548900f5295727e2e2 256 SUPERFAMILY SSF51735 6 254 4.31E-71 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS28045 a31c278b68e2f1548900f5295727e2e2 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 253 4.0E-56 T 06-07-2017 BWK49_RS28045 a31c278b68e2f1548900f5295727e2e2 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 6.9E-27 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS28045 a31c278b68e2f1548900f5295727e2e2 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 6.9E-27 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS28045 a31c278b68e2f1548900f5295727e2e2 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 6.9E-27 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS28045 a31c278b68e2f1548900f5295727e2e2 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 6.9E-27 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS28045 a31c278b68e2f1548900f5295727e2e2 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 6.9E-27 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS28415 b71a5bd3ffec2a7ba5222fe9b2a5768b 307 SUPERFAMILY SSF159659 12 267 9.68E-88 T 06-07-2017 BWK49_RS28415 b71a5bd3ffec2a7ba5222fe9b2a5768b 307 Gene3D G3DSA:1.10.287.100 224 265 7.9E-19 T 06-07-2017 IPR013028 Transcription factor IIA, alpha subunit, N-terminal GO:0006367 BWK49_RS28415 b71a5bd3ffec2a7ba5222fe9b2a5768b 307 Pfam PF09754 PAC2 family 26 242 4.0E-44 T 06-07-2017 IPR019151 Proteasome assembly chaperone 2 BWK49_RS28415 b71a5bd3ffec2a7ba5222fe9b2a5768b 307 PIRSF PIRSF028754 3 304 6.3E-126 T 06-07-2017 IPR008492 Protein of unknown function DUF774 BWK49_RS23740 5e2a742374df2da952addc782ed897f6 788 Pfam PF03632 Glycosyl hydrolase family 65 central catalytic domain 327 693 1.3E-141 T 06-07-2017 IPR005195 Glycoside hydrolase, family 65, central catalytic GO:0003824|GO:0005975 BWK49_RS23740 5e2a742374df2da952addc782ed897f6 788 Gene3D G3DSA:2.70.98.40 4 270 7.7E-75 T 06-07-2017 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 BWK49_RS23740 5e2a742374df2da952addc782ed897f6 788 PIRSF PIRSF036289 1 762 1.3E-218 T 06-07-2017 IPR017045 Maltose phosphorylase/glycosyl hydrolase/vacuolar acid trehalase BWK49_RS23740 5e2a742374df2da952addc782ed897f6 788 Gene3D G3DSA:2.60.420.10 681 753 4.2E-20 T 06-07-2017 BWK49_RS23740 5e2a742374df2da952addc782ed897f6 788 SUPERFAMILY SSF48208 284 746 1.77E-114 T 06-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 BWK49_RS23740 5e2a742374df2da952addc782ed897f6 788 SUPERFAMILY SSF74650 5 270 7.22E-66 T 06-07-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 BWK49_RS23740 5e2a742374df2da952addc782ed897f6 788 Gene3D G3DSA:1.50.10.10 321 680 8.8E-122 T 06-07-2017 IPR012341 Six-hairpin glycosidase GO:0003824 BWK49_RS23740 5e2a742374df2da952addc782ed897f6 788 Pfam PF03636 Glycosyl hydrolase family 65, N-terminal domain 16 270 6.3E-59 T 06-07-2017 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 BWK49_RS23740 5e2a742374df2da952addc782ed897f6 788 Pfam PF03633 Glycosyl hydrolase family 65, C-terminal domain 698 750 5.5E-14 T 06-07-2017 IPR005194 Glycoside hydrolase family 65, C-terminal BWK49_RS06320 09489f5e56cda424682e2ff4f82fea2b 233 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 124 152 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS06320 09489f5e56cda424682e2ff4f82fea2b 233 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 111 127 1.7E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS06320 09489f5e56cda424682e2ff4f82fea2b 233 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 175 1.7E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS06320 09489f5e56cda424682e2ff4f82fea2b 233 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 195 215 1.7E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS06320 09489f5e56cda424682e2ff4f82fea2b 233 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 137 156 1.7E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS06320 09489f5e56cda424682e2ff4f82fea2b 233 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 1.7E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS06320 09489f5e56cda424682e2ff4f82fea2b 233 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 64 75 1.7E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS06320 09489f5e56cda424682e2ff4f82fea2b 233 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 64 75 1.0E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS06320 09489f5e56cda424682e2ff4f82fea2b 233 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 117 125 1.0E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS06320 09489f5e56cda424682e2ff4f82fea2b 233 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 156 1.0E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS06320 09489f5e56cda424682e2ff4f82fea2b 233 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 230 1.6E-59 T 06-07-2017 BWK49_RS06320 09489f5e56cda424682e2ff4f82fea2b 233 SUPERFAMILY SSF51735 2 231 5.38E-79 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS06320 09489f5e56cda424682e2ff4f82fea2b 233 Gene3D G3DSA:3.40.50.720 2 231 8.5E-81 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS06320 09489f5e56cda424682e2ff4f82fea2b 233 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2 168 2.1E-5 T 06-07-2017 BWK49_RS25395 138bab0ef7c8c9fcac4d15421bf89ce3 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 2.9E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS25395 138bab0ef7c8c9fcac4d15421bf89ce3 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 168 2.9E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS25395 138bab0ef7c8c9fcac4d15421bf89ce3 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 139 2.9E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS25395 138bab0ef7c8c9fcac4d15421bf89ce3 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 2.9E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS25395 138bab0ef7c8c9fcac4d15421bf89ce3 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 2.9E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS25395 138bab0ef7c8c9fcac4d15421bf89ce3 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 129 137 1.9E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS25395 138bab0ef7c8c9fcac4d15421bf89ce3 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 1.9E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS25395 138bab0ef7c8c9fcac4d15421bf89ce3 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 168 1.9E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS25395 138bab0ef7c8c9fcac4d15421bf89ce3 249 SUPERFAMILY SSF51735 7 227 6.96E-59 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS25395 138bab0ef7c8c9fcac4d15421bf89ce3 249 Pfam PF00106 short chain dehydrogenase 10 186 3.8E-45 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS25395 138bab0ef7c8c9fcac4d15421bf89ce3 249 Gene3D G3DSA:3.40.50.720 8 225 4.6E-60 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS01130 b294a52fecb8b5bf92e6f9121ebe62e0 396 Gene3D G3DSA:3.40.50.720 188 265 4.0E-44 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS01130 b294a52fecb8b5bf92e6f9121ebe62e0 396 Gene3D G3DSA:3.40.50.720 1 84 4.0E-44 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS01130 b294a52fecb8b5bf92e6f9121ebe62e0 396 Gene3D G3DSA:3.40.50.720 338 386 4.0E-44 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS01130 b294a52fecb8b5bf92e6f9121ebe62e0 396 SUPERFAMILY SSF54373 256 327 4.71E-24 T 06-07-2017 BWK49_RS01130 b294a52fecb8b5bf92e6f9121ebe62e0 396 Pfam PF13450 NAD(P)-binding Rossmann-like domain 9 78 2.2E-17 T 06-07-2017 BWK49_RS01130 b294a52fecb8b5bf92e6f9121ebe62e0 396 SUPERFAMILY SSF51971 348 381 2.12E-44 T 06-07-2017 BWK49_RS01130 b294a52fecb8b5bf92e6f9121ebe62e0 396 SUPERFAMILY SSF51971 5 275 2.12E-44 T 06-07-2017 BWK49_RS01130 b294a52fecb8b5bf92e6f9121ebe62e0 396 Pfam PF03275 UDP-galactopyranose mutase 153 363 6.3E-80 T 06-07-2017 IPR015899 UDP-galactopyranose mutase, C-terminal GO:0008767 KEGG: 00052+5.4.99.9|KEGG: 00520+5.4.99.9|MetaCyc: PWY-6397|MetaCyc: PWY-7328|MetaCyc: PWY-7622 BWK49_RS01130 b294a52fecb8b5bf92e6f9121ebe62e0 396 TIGRFAM TIGR00031 UDP-GALP_mutase: UDP-galactopyranose mutase 5 381 1.0E-101 T 06-07-2017 IPR004379 UDP-galactopyranose mutase GO:0008767 KEGG: 00052+5.4.99.9|KEGG: 00520+5.4.99.9|MetaCyc: PWY-6397|MetaCyc: PWY-7328|MetaCyc: PWY-7622 BWK49_RS15545 fe52ec90f9053ccf45a912e68477c34e 777 Pfam PF02515 CoA-transferase family III 6 362 6.1E-58 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 BWK49_RS15545 fe52ec90f9053ccf45a912e68477c34e 777 Pfam PF02515 CoA-transferase family III 394 761 4.4E-101 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 BWK49_RS15545 fe52ec90f9053ccf45a912e68477c34e 777 SUPERFAMILY SSF89796 390 768 6.8E-101 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS15545 fe52ec90f9053ccf45a912e68477c34e 777 Gene3D G3DSA:3.40.50.10540 693 771 5.3E-77 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS15545 fe52ec90f9053ccf45a912e68477c34e 777 Gene3D G3DSA:3.40.50.10540 3 204 3.0E-52 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS15545 fe52ec90f9053ccf45a912e68477c34e 777 Gene3D G3DSA:3.40.50.10540 392 604 5.3E-77 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS15545 fe52ec90f9053ccf45a912e68477c34e 777 Gene3D G3DSA:3.40.50.10540 295 370 3.0E-52 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS15545 fe52ec90f9053ccf45a912e68477c34e 777 SUPERFAMILY SSF89796 2 373 3.53E-69 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS15545 fe52ec90f9053ccf45a912e68477c34e 777 Gene3D G3DSA:3.30.1540.10 611 692 6.3E-27 T 06-07-2017 BWK49_RS15545 fe52ec90f9053ccf45a912e68477c34e 777 Gene3D G3DSA:3.30.1540.10 222 294 6.7E-9 T 06-07-2017 BWK49_RS20945 67423828eba0ace17b9cfa3031b0d354 622 Gene3D G3DSA:3.40.50.970 403 607 6.0E-76 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS20945 67423828eba0ace17b9cfa3031b0d354 622 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 43 208 1.1E-55 T 06-07-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 BWK49_RS20945 67423828eba0ace17b9cfa3031b0d354 622 SUPERFAMILY SSF52518 407 609 6.97E-69 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS20945 67423828eba0ace17b9cfa3031b0d354 622 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 467 486 - T 06-07-2017 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 BWK49_RS20945 67423828eba0ace17b9cfa3031b0d354 622 Gene3D G3DSA:3.40.50.970 41 218 1.7E-72 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS20945 67423828eba0ace17b9cfa3031b0d354 622 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 42 605 2.0E-234 T 06-07-2017 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 BWK49_RS20945 67423828eba0ace17b9cfa3031b0d354 622 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 232 367 2.6E-50 T 06-07-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 BWK49_RS20945 67423828eba0ace17b9cfa3031b0d354 622 SUPERFAMILY SSF52467 224 397 9.65E-63 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain BWK49_RS20945 67423828eba0ace17b9cfa3031b0d354 622 Gene3D G3DSA:3.40.50.1220 227 397 1.0E-68 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain BWK49_RS20945 67423828eba0ace17b9cfa3031b0d354 622 SUPERFAMILY SSF52518 39 222 3.22E-61 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS20945 67423828eba0ace17b9cfa3031b0d354 622 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 430 583 2.4E-51 T 06-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 BWK49_RS25190 a28e3d35faf86ae3914a5d7fdc5dd5c6 1188 TIGRFAM TIGR01746 Thioester-redct: thioester reductase domain 785 1179 1.2E-82 T 06-07-2017 IPR010080 Thioester reductase-like domain BWK49_RS25190 a28e3d35faf86ae3914a5d7fdc5dd5c6 1188 Gene3D G3DSA:3.40.50.720 785 1083 1.7E-27 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS25190 a28e3d35faf86ae3914a5d7fdc5dd5c6 1188 Pfam PF00501 AMP-binding enzyme 82 524 8.7E-68 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS25190 a28e3d35faf86ae3914a5d7fdc5dd5c6 1188 SUPERFAMILY SSF56801 47 651 2.62E-90 T 06-07-2017 BWK49_RS25190 a28e3d35faf86ae3914a5d7fdc5dd5c6 1188 SUPERFAMILY SSF51735 785 1105 4.25E-27 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS25190 a28e3d35faf86ae3914a5d7fdc5dd5c6 1188 Gene3D G3DSA:3.40.50.980 262 434 1.5E-21 T 06-07-2017 BWK49_RS25190 a28e3d35faf86ae3914a5d7fdc5dd5c6 1188 Pfam PF07993 Male sterility protein 788 1050 2.1E-50 T 06-07-2017 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 BWK49_RS25190 a28e3d35faf86ae3914a5d7fdc5dd5c6 1188 Pfam PF00550 Phosphopantetheine attachment site 663 730 9.9E-8 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS25190 a28e3d35faf86ae3914a5d7fdc5dd5c6 1188 SUPERFAMILY SSF47336 661 744 1.57E-9 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS25190 a28e3d35faf86ae3914a5d7fdc5dd5c6 1188 Gene3D G3DSA:1.10.1200.10 660 733 9.6E-10 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS25190 a28e3d35faf86ae3914a5d7fdc5dd5c6 1188 Gene3D G3DSA:3.40.50.980 86 198 2.5E-27 T 06-07-2017 BWK49_RS25190 a28e3d35faf86ae3914a5d7fdc5dd5c6 1188 Gene3D G3DSA:3.40.50.980 230 261 2.5E-27 T 06-07-2017 BWK49_RS25190 a28e3d35faf86ae3914a5d7fdc5dd5c6 1188 Gene3D G3DSA:2.30.38.10 443 503 8.9E-10 T 06-07-2017 BWK49_RS25190 a28e3d35faf86ae3914a5d7fdc5dd5c6 1188 ProSitePatterns PS00455 Putative AMP-binding domain signature. 256 267 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS07490 74324a1a445dcdc00f71505e557aee31 449 PRINTS PR01181 Diaminopimelate decarboxylase signature 186 195 6.7E-24 T 06-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 BWK49_RS07490 74324a1a445dcdc00f71505e557aee31 449 PRINTS PR01181 Diaminopimelate decarboxylase signature 332 350 6.7E-24 T 06-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 BWK49_RS07490 74324a1a445dcdc00f71505e557aee31 449 PRINTS PR01181 Diaminopimelate decarboxylase signature 415 437 6.7E-24 T 06-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 BWK49_RS07490 74324a1a445dcdc00f71505e557aee31 449 PRINTS PR01181 Diaminopimelate decarboxylase signature 100 117 6.7E-24 T 06-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 BWK49_RS07490 74324a1a445dcdc00f71505e557aee31 449 Gene3D G3DSA:3.20.20.10 59 298 1.3E-78 T 06-07-2017 IPR029066 PLP-binding barrel BWK49_RS07490 74324a1a445dcdc00f71505e557aee31 449 SUPERFAMILY SSF50621 290 447 8.58E-47 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 BWK49_RS07490 74324a1a445dcdc00f71505e557aee31 449 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 322 424 3.5E-16 T 06-07-2017 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 BWK49_RS07490 74324a1a445dcdc00f71505e557aee31 449 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 82 100 - T 06-07-2017 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site BWK49_RS07490 74324a1a445dcdc00f71505e557aee31 449 SUPERFAMILY SSF51419 50 315 1.26E-69 T 06-07-2017 IPR029066 PLP-binding barrel BWK49_RS07490 74324a1a445dcdc00f71505e557aee31 449 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 58 313 2.3E-55 T 06-07-2017 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 BWK49_RS07490 74324a1a445dcdc00f71505e557aee31 449 Gene3D G3DSA:2.40.37.10 299 447 1.4E-44 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 BWK49_RS07490 74324a1a445dcdc00f71505e557aee31 449 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 39 448 36.932 T 06-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 BWK49_RS07490 74324a1a445dcdc00f71505e557aee31 449 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 405 418 1.4E-15 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 BWK49_RS07490 74324a1a445dcdc00f71505e557aee31 449 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 102 114 1.4E-15 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 BWK49_RS07490 74324a1a445dcdc00f71505e557aee31 449 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 214 227 1.4E-15 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 BWK49_RS07490 74324a1a445dcdc00f71505e557aee31 449 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 303 322 1.4E-15 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 BWK49_RS07490 74324a1a445dcdc00f71505e557aee31 449 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 30 447 1.7E-128 T 06-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 BWK49_RS05070 dde4493c99b22b74decf25bfcbf519d1 365 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 30 138 2.0E-23 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 BWK49_RS05070 dde4493c99b22b74decf25bfcbf519d1 365 SUPERFAMILY SSF50129 4 186 6.51E-36 T 06-07-2017 IPR011032 GroES-like BWK49_RS05070 dde4493c99b22b74decf25bfcbf519d1 365 Gene3D G3DSA:3.40.50.720 190 304 2.4E-20 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS05070 dde4493c99b22b74decf25bfcbf519d1 365 Gene3D G3DSA:3.90.180.10 3 189 2.4E-41 T 06-07-2017 IPR011032 GroES-like BWK49_RS05070 dde4493c99b22b74decf25bfcbf519d1 365 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 06-07-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 BWK49_RS05070 dde4493c99b22b74decf25bfcbf519d1 365 Pfam PF00107 Zinc-binding dehydrogenase 189 320 4.4E-21 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 BWK49_RS05070 dde4493c99b22b74decf25bfcbf519d1 365 SUPERFAMILY SSF51735 154 318 8.02E-22 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS26205 4aa662fa67f1b361253db7d0dabf97f1 440 Pfam PF00083 Sugar (and other) transporter 293 425 3.3E-5 T 06-07-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 BWK49_RS26205 4aa662fa67f1b361253db7d0dabf97f1 440 Pfam PF00083 Sugar (and other) transporter 29 240 1.1E-24 T 06-07-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 BWK49_RS26205 4aa662fa67f1b361253db7d0dabf97f1 440 SUPERFAMILY SSF103473 16 437 2.75E-52 T 06-07-2017 IPR020846 Major facilitator superfamily domain BWK49_RS26205 4aa662fa67f1b361253db7d0dabf97f1 440 Gene3D G3DSA:1.20.1250.20 42 233 6.5E-22 T 06-07-2017 BWK49_RS26205 4aa662fa67f1b361253db7d0dabf97f1 440 Gene3D G3DSA:1.20.1250.20 255 434 3.1E-9 T 06-07-2017 BWK49_RS23410 85c421dfa97aa656a3dbd78cf4d56386 362 Hamap MF_00540 Adenosine deaminase [add]. 8 353 55.695 T 06-07-2017 IPR028893 Adenosine deaminase GO:0004000|GO:0009168 KEGG: 00230+3.5.4.4|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-74217 BWK49_RS23410 85c421dfa97aa656a3dbd78cf4d56386 362 SUPERFAMILY SSF51556 5 351 5.11E-71 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS23410 85c421dfa97aa656a3dbd78cf4d56386 362 Gene3D G3DSA:3.20.20.140 10 352 1.3E-101 T 06-07-2017 BWK49_RS23410 85c421dfa97aa656a3dbd78cf4d56386 362 Pfam PF00962 Adenosine/AMP deaminase 13 351 1.1E-103 T 06-07-2017 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 BWK49_RS23410 85c421dfa97aa656a3dbd78cf4d56386 362 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 14 351 3.8E-73 T 06-07-2017 IPR006330 Adenosine/adenine deaminase GO:0019239 Reactome: R-HSA-74217 BWK49_RS20510 763c31904b93fb48bda68a3e5496b250 266 SUPERFAMILY SSF47413 11 74 2.96E-8 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 BWK49_RS20510 763c31904b93fb48bda68a3e5496b250 266 SUPERFAMILY SSF56024 68 173 2.54E-6 T 06-07-2017 BWK49_RS20510 763c31904b93fb48bda68a3e5496b250 266 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 17 74 4.0E-6 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 BWK49_RS20510 763c31904b93fb48bda68a3e5496b250 266 SMART SM00530 17 73 7.1E-8 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 BWK49_RS20510 763c31904b93fb48bda68a3e5496b250 266 Gene3D G3DSA:1.10.260.40 12 74 3.1E-9 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 BWK49_RS20510 763c31904b93fb48bda68a3e5496b250 266 Gene3D G3DSA:3.30.870.10 136 169 1.4E-4 T 06-07-2017 BWK49_RS06125 06538881db7e5e4aeeb8fed9d13e8368 62 PRINTS PR00352 3Fe-4S ferredoxin signature 16 26 3.4E-6 T 06-07-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 BWK49_RS06125 06538881db7e5e4aeeb8fed9d13e8368 62 PRINTS PR00352 3Fe-4S ferredoxin signature 47 59 3.4E-6 T 06-07-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 BWK49_RS06125 06538881db7e5e4aeeb8fed9d13e8368 62 PRINTS PR00352 3Fe-4S ferredoxin signature 5 16 3.4E-6 T 06-07-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 BWK49_RS06125 06538881db7e5e4aeeb8fed9d13e8368 62 SUPERFAMILY SSF54862 2 60 8.25E-13 T 06-07-2017 BWK49_RS06125 06538881db7e5e4aeeb8fed9d13e8368 62 Gene3D G3DSA:3.30.70.20 1 60 2.4E-19 T 06-07-2017 BWK49_RS06125 06538881db7e5e4aeeb8fed9d13e8368 62 Pfam PF13459 4Fe-4S single cluster domain 3 60 7.4E-17 T 06-07-2017 BWK49_RS06170 139bcbdfd7bfb92794c1ac912c7a7810 307 Gene3D G3DSA:3.40.50.720 6 291 2.5E-37 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS06170 139bcbdfd7bfb92794c1ac912c7a7810 307 Pfam PF01370 NAD dependent epimerase/dehydratase family 7 219 7.8E-19 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 BWK49_RS06170 139bcbdfd7bfb92794c1ac912c7a7810 307 SUPERFAMILY SSF51735 5 291 5.46E-43 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS20355 6f770e04b395efb1ecae9109ec41ddcc 122 Gene3D G3DSA:3.10.180.10 4 119 3.0E-30 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS20355 6f770e04b395efb1ecae9109ec41ddcc 122 SUPERFAMILY SSF54593 2 121 3.89E-28 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS20355 6f770e04b395efb1ecae9109ec41ddcc 122 Pfam PF12681 Glyoxalase-like domain 6 121 2.7E-16 T 06-07-2017 IPR025870 Glyoxalase-like domain BWK49_RS18580 751ede7ef89b70aabdb2f8433e12b4bf 174 Pfam PF01202 Shikimate kinase 11 166 3.3E-45 T 06-07-2017 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 BWK49_RS18580 751ede7ef89b70aabdb2f8433e12b4bf 174 ProSitePatterns PS01128 Shikimate kinase signature. 58 83 - T 06-07-2017 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 BWK49_RS18580 751ede7ef89b70aabdb2f8433e12b4bf 174 SUPERFAMILY SSF52540 2 165 3.11E-28 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS18580 751ede7ef89b70aabdb2f8433e12b4bf 174 Gene3D G3DSA:3.40.50.300 4 167 4.3E-49 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS18580 751ede7ef89b70aabdb2f8433e12b4bf 174 Hamap MF_00109 Shikimate kinase [aroK]. 2 167 26.531 T 06-07-2017 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 BWK49_RS18580 751ede7ef89b70aabdb2f8433e12b4bf 174 PRINTS PR01100 Shikimate kinase family signature 29 42 1.4E-20 T 06-07-2017 BWK49_RS18580 751ede7ef89b70aabdb2f8433e12b4bf 174 PRINTS PR01100 Shikimate kinase family signature 57 65 1.4E-20 T 06-07-2017 BWK49_RS18580 751ede7ef89b70aabdb2f8433e12b4bf 174 PRINTS PR01100 Shikimate kinase family signature 5 20 1.4E-20 T 06-07-2017 BWK49_RS18580 751ede7ef89b70aabdb2f8433e12b4bf 174 PRINTS PR01100 Shikimate kinase family signature 75 84 1.4E-20 T 06-07-2017 BWK49_RS18580 751ede7ef89b70aabdb2f8433e12b4bf 174 PRINTS PR01100 Shikimate kinase family signature 95 112 1.4E-20 T 06-07-2017 BWK49_RS13210 bef6ceda1941a4ccfc37e9f5041e5174 871 SMART SM00421 799 856 1.4E-21 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS13210 bef6ceda1941a4ccfc37e9f5041e5174 871 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 816 832 1.2E-9 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS13210 bef6ceda1941a4ccfc37e9f5041e5174 871 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 802 816 1.2E-9 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS13210 bef6ceda1941a4ccfc37e9f5041e5174 871 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 832 844 1.2E-9 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS13210 bef6ceda1941a4ccfc37e9f5041e5174 871 SUPERFAMILY SSF52540 4 200 1.61E-13 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS13210 bef6ceda1941a4ccfc37e9f5041e5174 871 Gene3D G3DSA:1.10.10.10 801 855 1.5E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS13210 bef6ceda1941a4ccfc37e9f5041e5174 871 Pfam PF00196 Bacterial regulatory proteins, luxR family 802 855 7.0E-16 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS13210 bef6ceda1941a4ccfc37e9f5041e5174 871 Gene3D G3DSA:3.40.50.300 6 127 8.9E-9 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS13210 bef6ceda1941a4ccfc37e9f5041e5174 871 SMART SM00382 12 151 1.4E-6 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS13210 bef6ceda1941a4ccfc37e9f5041e5174 871 SUPERFAMILY SSF46894 794 856 3.4E-18 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 BWK49_RS13210 bef6ceda1941a4ccfc37e9f5041e5174 871 Pfam PF13401 AAA domain 17 112 1.3E-7 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS13210 bef6ceda1941a4ccfc37e9f5041e5174 871 ProSitePatterns PS00622 LuxR-type HTH domain signature. 816 843 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS16305 86034d1601d4acc19fd5c87a6d9698b2 398 Gene3D G3DSA:1.10.287.130 145 209 9.9E-7 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 BWK49_RS16305 86034d1601d4acc19fd5c87a6d9698b2 398 Gene3D G3DSA:3.30.565.10 222 379 7.7E-45 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS16305 86034d1601d4acc19fd5c87a6d9698b2 398 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 265 377 1.8E-24 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS16305 86034d1601d4acc19fd5c87a6d9698b2 398 PRINTS PR00344 Bacterial sensor protein C-terminal signature 362 375 1.4E-16 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 BWK49_RS16305 86034d1601d4acc19fd5c87a6d9698b2 398 PRINTS PR00344 Bacterial sensor protein C-terminal signature 320 330 1.4E-16 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 BWK49_RS16305 86034d1601d4acc19fd5c87a6d9698b2 398 PRINTS PR00344 Bacterial sensor protein C-terminal signature 337 355 1.4E-16 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 BWK49_RS16305 86034d1601d4acc19fd5c87a6d9698b2 398 PRINTS PR00344 Bacterial sensor protein C-terminal signature 302 316 1.4E-16 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 BWK49_RS16305 86034d1601d4acc19fd5c87a6d9698b2 398 SUPERFAMILY SSF55874 210 378 4.71E-44 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS16305 86034d1601d4acc19fd5c87a6d9698b2 398 SUPERFAMILY SSF158472 101 151 5.89E-6 T 06-07-2017 BWK49_RS16305 86034d1601d4acc19fd5c87a6d9698b2 398 Pfam PF00672 HAMP domain 82 150 3.6E-11 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 BWK49_RS16305 86034d1601d4acc19fd5c87a6d9698b2 398 SMART SM00387 265 378 3.4E-38 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS16305 86034d1601d4acc19fd5c87a6d9698b2 398 SMART SM00304 101 154 5.8E-8 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 BWK49_RS16305 86034d1601d4acc19fd5c87a6d9698b2 398 SUPERFAMILY SSF47384 138 218 3.14E-10 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 BWK49_RS16305 86034d1601d4acc19fd5c87a6d9698b2 398 SMART SM00388 155 219 9.0E-4 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 BWK49_RS05105 db0be3514edad9aa7db2bfdbfab35f06 397 SUPERFAMILY SSF48264 10 394 1.57E-98 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS05105 db0be3514edad9aa7db2bfdbfab35f06 397 Pfam PF00067 Cytochrome P450 42 364 6.7E-26 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS05105 db0be3514edad9aa7db2bfdbfab35f06 397 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 338 347 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 BWK49_RS05105 db0be3514edad9aa7db2bfdbfab35f06 397 PRINTS PR00359 B-class P450 signature 336 345 2.6E-58 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS05105 db0be3514edad9aa7db2bfdbfab35f06 397 PRINTS PR00359 B-class P450 signature 270 281 2.6E-58 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS05105 db0be3514edad9aa7db2bfdbfab35f06 397 PRINTS PR00359 B-class P450 signature 287 314 2.6E-58 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS05105 db0be3514edad9aa7db2bfdbfab35f06 397 PRINTS PR00359 B-class P450 signature 345 356 2.6E-58 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS05105 db0be3514edad9aa7db2bfdbfab35f06 397 PRINTS PR00359 B-class P450 signature 85 96 2.6E-58 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS05105 db0be3514edad9aa7db2bfdbfab35f06 397 PRINTS PR00359 B-class P450 signature 132 148 2.6E-58 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS05105 db0be3514edad9aa7db2bfdbfab35f06 397 PRINTS PR00359 B-class P450 signature 315 330 2.6E-58 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS05105 db0be3514edad9aa7db2bfdbfab35f06 397 PRINTS PR00359 B-class P450 signature 149 164 2.6E-58 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS05105 db0be3514edad9aa7db2bfdbfab35f06 397 PRINTS PR00359 B-class P450 signature 189 211 2.6E-58 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS05105 db0be3514edad9aa7db2bfdbfab35f06 397 PRINTS PR00385 P450 superfamily signature 336 345 5.2E-7 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS05105 db0be3514edad9aa7db2bfdbfab35f06 397 PRINTS PR00385 P450 superfamily signature 270 281 5.2E-7 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS05105 db0be3514edad9aa7db2bfdbfab35f06 397 PRINTS PR00385 P450 superfamily signature 345 356 5.2E-7 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS05105 db0be3514edad9aa7db2bfdbfab35f06 397 PRINTS PR00385 P450 superfamily signature 235 252 5.2E-7 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS05105 db0be3514edad9aa7db2bfdbfab35f06 397 Gene3D G3DSA:1.10.630.10 8 395 5.7E-125 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS07295 ea99bfe4731687a166980799d738b1ae 500 Pfam PF04932 O-Antigen ligase 248 406 1.2E-9 T 06-07-2017 IPR007016 O-antigen ligase-related BWK49_RS04385 60ce80e2712fb429ec715df7e5f98318 1032 SUPERFAMILY SSF52540 102 352 1.21E-29 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS04385 60ce80e2712fb429ec715df7e5f98318 1032 TIGRFAM TIGR03925 T7SS_EccC_b: type VII secretion protein EccCb 417 1025 6.9E-135 T 06-07-2017 IPR023837 EccCb-like, Actinobacteria BWK49_RS04385 60ce80e2712fb429ec715df7e5f98318 1032 Gene3D G3DSA:3.40.50.300 105 354 1.6E-30 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS04385 60ce80e2712fb429ec715df7e5f98318 1032 Gene3D G3DSA:3.40.50.300 803 869 2.0E-4 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS04385 60ce80e2712fb429ec715df7e5f98318 1032 Pfam PF01580 FtsK/SpoIIIE family 448 681 1.6E-33 T 06-07-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 BWK49_RS04385 60ce80e2712fb429ec715df7e5f98318 1032 Pfam PF01580 FtsK/SpoIIIE family 96 329 1.0E-25 T 06-07-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 BWK49_RS22020 39656efd6e648a3fe2108a2c3bd3f63d 804 ProSitePatterns PS00642 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. 117 129 - T 06-07-2017 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS22020 39656efd6e648a3fe2108a2c3bd3f63d 804 SUPERFAMILY SSF53706 226 684 2.05E-77 T 06-07-2017 BWK49_RS22020 39656efd6e648a3fe2108a2c3bd3f63d 804 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 48 65 - T 06-07-2017 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS22020 39656efd6e648a3fe2108a2c3bd3f63d 804 SUPERFAMILY SSF50692 706 782 1.2E-10 T 06-07-2017 IPR009010 Aspartate decarboxylase-like domain BWK49_RS22020 39656efd6e648a3fe2108a2c3bd3f63d 804 Gene3D G3DSA:3.10.20.30 18 80 7.9E-7 T 06-07-2017 IPR012675 Beta-grasp domain BWK49_RS22020 39656efd6e648a3fe2108a2c3bd3f63d 804 SUPERFAMILY SSF54862 95 231 3.1E-30 T 06-07-2017 BWK49_RS22020 39656efd6e648a3fe2108a2c3bd3f63d 804 TIGRFAM TIGR01973 NuoG: NADH dehydrogenase (quinone), G subunit 21 655 3.7E-167 T 06-07-2017 IPR010228 NADH:ubiquinone oxidoreductase, subunit G GO:0016651|GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS22020 39656efd6e648a3fe2108a2c3bd3f63d 804 Gene3D G3DSA:3.30.70.20 218 243 6.1E-4 T 06-07-2017 BWK49_RS22020 39656efd6e648a3fe2108a2c3bd3f63d 804 Pfam PF01568 Molydopterin dinucleotide binding domain 726 783 1.2E-8 T 06-07-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 BWK49_RS22020 39656efd6e648a3fe2108a2c3bd3f63d 804 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 17 92 1.9E-19 T 06-07-2017 BWK49_RS22020 39656efd6e648a3fe2108a2c3bd3f63d 804 Gene3D G3DSA:2.20.25.90 244 289 3.3E-10 T 06-07-2017 BWK49_RS22020 39656efd6e648a3fe2108a2c3bd3f63d 804 Gene3D G3DSA:3.40.50.740 485 692 6.6E-36 T 06-07-2017 BWK49_RS22020 39656efd6e648a3fe2108a2c3bd3f63d 804 Gene3D G3DSA:3.40.50.740 293 364 6.6E-36 T 06-07-2017 BWK49_RS22020 39656efd6e648a3fe2108a2c3bd3f63d 804 SUPERFAMILY SSF54292 18 91 6.13E-21 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 BWK49_RS22020 39656efd6e648a3fe2108a2c3bd3f63d 804 SMART SM00929 102 142 2.0E-17 T 06-07-2017 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS22020 39656efd6e648a3fe2108a2c3bd3f63d 804 SMART SM00926 235 289 9.0E-5 T 06-07-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS22020 39656efd6e648a3fe2108a2c3bd3f63d 804 Pfam PF00384 Molybdopterin oxidoreductase 293 432 4.5E-9 T 06-07-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS22020 39656efd6e648a3fe2108a2c3bd3f63d 804 Gene3D G3DSA:2.40.40.20 704 781 5.8E-9 T 06-07-2017 BWK49_RS22020 39656efd6e648a3fe2108a2c3bd3f63d 804 Gene3D G3DSA:3.30.70.20 155 217 1.7E-4 T 06-07-2017 BWK49_RS22020 39656efd6e648a3fe2108a2c3bd3f63d 804 Gene3D G3DSA:3.40.228.10 376 457 7.2E-6 T 06-07-2017 BWK49_RS22020 39656efd6e648a3fe2108a2c3bd3f63d 804 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 103 141 1.1E-14 T 06-07-2017 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS22020 39656efd6e648a3fe2108a2c3bd3f63d 804 ProSitePatterns PS00643 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. 165 175 - T 06-07-2017 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS13255 e40e2cdc130814969fbd0fb923d9c60b 579 Pfam PF00501 AMP-binding enzyme 12 467 3.2E-77 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS13255 e40e2cdc130814969fbd0fb923d9c60b 579 SUPERFAMILY SSF56801 5 572 1.57E-96 T 06-07-2017 BWK49_RS13255 e40e2cdc130814969fbd0fb923d9c60b 579 Gene3D G3DSA:3.30.300.30 459 567 3.6E-13 T 06-07-2017 BWK49_RS13255 e40e2cdc130814969fbd0fb923d9c60b 579 Gene3D G3DSA:2.30.38.10 383 457 3.1E-17 T 06-07-2017 BWK49_RS13255 e40e2cdc130814969fbd0fb923d9c60b 579 Gene3D G3DSA:3.40.50.980 178 344 7.4E-30 T 06-07-2017 BWK49_RS13255 e40e2cdc130814969fbd0fb923d9c60b 579 Gene3D G3DSA:3.40.50.980 4 177 2.5E-29 T 06-07-2017 BWK49_RS08405 08b145fe8917065f36df6674aae09eb8 181 SUPERFAMILY SSF54637 25 179 1.54E-18 T 06-07-2017 IPR029069 HotDog domain BWK49_RS08405 08b145fe8917065f36df6674aae09eb8 181 Gene3D G3DSA:3.10.129.10 26 178 2.9E-24 T 06-07-2017 IPR029069 HotDog domain BWK49_RS08405 08b145fe8917065f36df6674aae09eb8 181 Pfam PF13452 N-terminal half of MaoC dehydratase 30 168 3.5E-17 T 06-07-2017 BWK49_RS20985 ccd4bc70a331516819a61dff4b9cd88e 99 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 20 91 3.0E-17 T 06-07-2017 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 BWK49_RS20985 ccd4bc70a331516819a61dff4b9cd88e 99 SUPERFAMILY SSF141000 3 94 3.14E-26 T 06-07-2017 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 BWK49_RS20985 ccd4bc70a331516819a61dff4b9cd88e 99 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 4 95 2.5E-30 T 06-07-2017 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 BWK49_RS20985 ccd4bc70a331516819a61dff4b9cd88e 99 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 3 96 23.87 T 06-07-2017 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 BWK49_RS12445 ff34f1bdb4ee63a95372a7a7ec140794 473 SUPERFAMILY SSF52096 184 458 4.68E-70 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS12445 ff34f1bdb4ee63a95372a7a7ec140794 473 SUPERFAMILY SSF52096 15 211 1.53E-46 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS12445 ff34f1bdb4ee63a95372a7a7ec140794 473 Pfam PF01039 Carboxyl transferase domain 38 459 1.9E-124 T 06-07-2017 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 BWK49_RS12445 ff34f1bdb4ee63a95372a7a7ec140794 473 Gene3D G3DSA:3.90.226.10 228 473 2.8E-74 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS12445 ff34f1bdb4ee63a95372a7a7ec140794 473 Gene3D G3DSA:3.90.226.10 15 210 5.2E-46 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS01885 71b9eac50882ee81bbadba0a4f5cf216 92 SUPERFAMILY SSF54862 4 70 3.09E-14 T 06-07-2017 BWK49_RS01885 71b9eac50882ee81bbadba0a4f5cf216 92 Pfam PF13187 4Fe-4S dicluster domain 10 64 4.8E-8 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain BWK49_RS01885 71b9eac50882ee81bbadba0a4f5cf216 92 Gene3D G3DSA:3.30.70.20 4 66 1.2E-11 T 06-07-2017 BWK49_RS01885 71b9eac50882ee81bbadba0a4f5cf216 92 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 10 21 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site BWK49_RS06850 03be3e2297901ed603f32df268f367af 358 SUPERFAMILY SSF51735 1 160 5.92E-11 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS06850 03be3e2297901ed603f32df268f367af 358 Gene3D G3DSA:3.40.50.720 1 213 9.2E-31 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS20000 c48c9e7ac5111d4c01614a26a6b6776a 165 PRINTS PR00446 Hydrogen uptake protein signature 17 28 2.6E-12 T 06-07-2017 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 BWK49_RS20000 c48c9e7ac5111d4c01614a26a6b6776a 165 PRINTS PR00446 Hydrogen uptake protein signature 58 68 2.6E-12 T 06-07-2017 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 BWK49_RS20000 c48c9e7ac5111d4c01614a26a6b6776a 165 PRINTS PR00446 Hydrogen uptake protein signature 36 53 2.6E-12 T 06-07-2017 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 BWK49_RS20000 c48c9e7ac5111d4c01614a26a6b6776a 165 PRINTS PR00446 Hydrogen uptake protein signature 69 85 2.6E-12 T 06-07-2017 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 BWK49_RS20000 c48c9e7ac5111d4c01614a26a6b6776a 165 PRINTS PR00446 Hydrogen uptake protein signature 5 17 2.6E-12 T 06-07-2017 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 BWK49_RS20000 c48c9e7ac5111d4c01614a26a6b6776a 165 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 6 148 6.6E-36 T 06-07-2017 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 BWK49_RS20000 c48c9e7ac5111d4c01614a26a6b6776a 165 SUPERFAMILY SSF53163 4 153 2.88E-34 T 06-07-2017 IPR023430 Peptidase HybD-like domain BWK49_RS20000 c48c9e7ac5111d4c01614a26a6b6776a 165 Pfam PF01750 Hydrogenase maturation protease 33 148 1.6E-16 T 06-07-2017 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 BWK49_RS20000 c48c9e7ac5111d4c01614a26a6b6776a 165 Gene3D G3DSA:3.40.50.1450 4 155 2.3E-43 T 06-07-2017 IPR023430 Peptidase HybD-like domain BWK49_RS19720 d1b3be8de9712c2c97f637da941bf933 1078 SMART SM00878 350 460 1.2E-40 T 06-07-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 BWK49_RS19720 d1b3be8de9712c2c97f637da941bf933 1078 Pfam PF01039 Carboxyl transferase domain 602 1071 9.1E-70 T 06-07-2017 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 BWK49_RS19720 d1b3be8de9712c2c97f637da941bf933 1078 Pfam PF02785 Biotin carboxylase C-terminal domain 350 461 2.1E-29 T 06-07-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 BWK49_RS19720 d1b3be8de9712c2c97f637da941bf933 1078 Gene3D G3DSA:2.40.50.100 488 555 2.0E-10 T 06-07-2017 BWK49_RS19720 d1b3be8de9712c2c97f637da941bf933 1078 Gene3D G3DSA:3.90.226.10 592 830 1.5E-40 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS19720 d1b3be8de9712c2c97f637da941bf933 1078 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 BWK49_RS19720 d1b3be8de9712c2c97f637da941bf933 1078 SUPERFAMILY SSF52440 4 111 1.73E-39 T 06-07-2017 IPR016185 Pre-ATP-grasp domain BWK49_RS19720 d1b3be8de9712c2c97f637da941bf933 1078 SUPERFAMILY SSF52096 803 1074 6.96E-57 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS19720 d1b3be8de9712c2c97f637da941bf933 1078 Gene3D G3DSA:3.30.1490.20 129 198 7.4E-16 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 BWK49_RS19720 d1b3be8de9712c2c97f637da941bf933 1078 SUPERFAMILY SSF56059 82 320 5.3E-50 T 06-07-2017 BWK49_RS19720 d1b3be8de9712c2c97f637da941bf933 1078 SUPERFAMILY SSF51230 482 555 1.83E-8 T 06-07-2017 IPR011053 Single hybrid motif BWK49_RS19720 d1b3be8de9712c2c97f637da941bf933 1078 Gene3D G3DSA:3.30.470.20 202 467 1.8E-73 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 BWK49_RS19720 d1b3be8de9712c2c97f637da941bf933 1078 Pfam PF00289 Biotin carboxylase, N-terminal domain 3 108 8.0E-39 T 06-07-2017 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 BWK49_RS19720 d1b3be8de9712c2c97f637da941bf933 1078 SUPERFAMILY SSF52096 579 834 1.61E-50 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS19720 d1b3be8de9712c2c97f637da941bf933 1078 Gene3D G3DSA:3.40.50.20 4 128 2.8E-42 T 06-07-2017 IPR016185 Pre-ATP-grasp domain BWK49_RS19720 d1b3be8de9712c2c97f637da941bf933 1078 SUPERFAMILY SSF51246 345 464 1.41E-29 T 06-07-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 BWK49_RS19720 d1b3be8de9712c2c97f637da941bf933 1078 Gene3D G3DSA:3.90.226.10 831 1073 3.9E-54 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS19720 d1b3be8de9712c2c97f637da941bf933 1078 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 320 7.6E-51 T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 BWK49_RS07620 ef74d007ce36e23747c317750ed6e2ca 251 Gene3D G3DSA:3.40.50.1820 9 248 5.2E-49 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS07620 ef74d007ce36e23747c317750ed6e2ca 251 Pfam PF01738 Dienelactone hydrolase family 24 248 1.3E-41 T 06-07-2017 IPR002925 Dienelactone hydrolase GO:0016787 BWK49_RS07620 ef74d007ce36e23747c317750ed6e2ca 251 SUPERFAMILY SSF53474 11 250 1.71E-43 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS03810 cc40300b62cf825638a75ea194f8427b 489 Gene3D G3DSA:3.40.309.10 272 459 2.9E-59 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 BWK49_RS03810 cc40300b62cf825638a75ea194f8427b 489 TIGRFAM TIGR04284 aldehy_Rv0768: aldehyde dehydrogenase, Rv0768 family 9 487 8.1E-283 T 06-07-2017 IPR026460 Aldehyde dehydrogenase, Rv0768 family BWK49_RS03810 cc40300b62cf825638a75ea194f8427b 489 SUPERFAMILY SSF53720 10 485 4.19E-146 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 BWK49_RS03810 cc40300b62cf825638a75ea194f8427b 489 Gene3D G3DSA:3.40.605.10 10 271 6.5E-75 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 BWK49_RS03810 cc40300b62cf825638a75ea194f8427b 489 Pfam PF00171 Aldehyde dehydrogenase family 21 484 1.8E-144 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 BWK49_RS03810 cc40300b62cf825638a75ea194f8427b 489 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 258 265 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 BWK49_RS24535 5349831a08bc0d77303230e341a82786 1396 Pfam PF10633 NPCBM-associated, NEW3 domain of alpha-galactosidase 1187 1262 8.9E-19 T 06-07-2017 IPR018905 Alpha-galactosidase, NEW3 domain BWK49_RS24535 5349831a08bc0d77303230e341a82786 1396 SUPERFAMILY SSF88688 395 502 2.68E-20 T 06-07-2017 IPR028995 Glycoside hydrolase families 57/38, central domain BWK49_RS24535 5349831a08bc0d77303230e341a82786 1396 Pfam PF01074 Glycosyl hydrolases family 38 N-terminal domain 94 397 2.0E-70 T 06-07-2017 IPR000602 Glycoside hydrolase family 38, N-terminal domain GO:0004559|GO:0005975 BWK49_RS24535 5349831a08bc0d77303230e341a82786 1396 Gene3D G3DSA:1.20.1270.50 397 494 4.7E-16 T 06-07-2017 IPR015341 Glycoside hydrolase family 38, central domain GO:0004553|GO:0008270 BWK49_RS24535 5349831a08bc0d77303230e341a82786 1396 SMART SM00872 402 473 2.4E-17 T 06-07-2017 IPR015341 Glycoside hydrolase family 38, central domain GO:0004553|GO:0008270 BWK49_RS24535 5349831a08bc0d77303230e341a82786 1396 Pfam PF07748 Glycosyl hydrolases family 38 C-terminal domain 499 713 1.2E-7 T 06-07-2017 IPR011682 Glycosyl hydrolase family 38, C-terminal GO:0006013|GO:0015923 BWK49_RS24535 5349831a08bc0d77303230e341a82786 1396 SUPERFAMILY SSF74650 496 726 5.34E-32 T 06-07-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 BWK49_RS24535 5349831a08bc0d77303230e341a82786 1396 Pfam PF09261 Alpha mannosidase middle domain 403 471 1.0E-11 T 06-07-2017 IPR015341 Glycoside hydrolase family 38, central domain GO:0004553|GO:0008270 BWK49_RS24535 5349831a08bc0d77303230e341a82786 1396 Gene3D G3DSA:3.20.110.10 88 396 7.3E-52 T 06-07-2017 IPR027291 Glycoside hydrolase 38/57, N-terminal domain BWK49_RS24535 5349831a08bc0d77303230e341a82786 1396 SUPERFAMILY SSF74650 940 1124 7.53E-7 T 06-07-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 BWK49_RS24535 5349831a08bc0d77303230e341a82786 1396 SUPERFAMILY SSF88713 88 376 1.48E-55 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 BWK49_RS24535 5349831a08bc0d77303230e341a82786 1396 Gene3D G3DSA:2.60.40.10 1171 1265 3.7E-12 T 06-07-2017 IPR013783 Immunoglobulin-like fold BWK49_RS17865 61da14a9bcef94ee7e84ae0202e4827c 269 PIRSF PIRSF000094 2 269 8.8E-103 T 06-07-2017 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 BWK49_RS17865 61da14a9bcef94ee7e84ae0202e4827c 269 Gene3D G3DSA:3.40.50.720 3 265 1.2E-56 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS17865 61da14a9bcef94ee7e84ae0202e4827c 269 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 264 7.5E-57 T 06-07-2017 BWK49_RS17865 61da14a9bcef94ee7e84ae0202e4827c 269 SUPERFAMILY SSF51735 4 265 1.58E-46 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS19775 6fcf0df8a061cc77bb150cff79d21df2 309 Gene3D G3DSA:3.10.20.30 216 307 1.9E-19 T 06-07-2017 IPR012675 Beta-grasp domain BWK49_RS19775 6fcf0df8a061cc77bb150cff79d21df2 309 Gene3D G3DSA:2.40.30.10 2 99 3.5E-31 T 06-07-2017 BWK49_RS19775 6fcf0df8a061cc77bb150cff79d21df2 309 PRINTS PR00409 Phthalate dioxygenase reductase family signature 89 103 5.3E-28 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 BWK49_RS19775 6fcf0df8a061cc77bb150cff79d21df2 309 PRINTS PR00409 Phthalate dioxygenase reductase family signature 39 51 5.3E-28 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 BWK49_RS19775 6fcf0df8a061cc77bb150cff79d21df2 309 PRINTS PR00409 Phthalate dioxygenase reductase family signature 111 130 5.3E-28 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 BWK49_RS19775 6fcf0df8a061cc77bb150cff79d21df2 309 PRINTS PR00409 Phthalate dioxygenase reductase family signature 188 196 5.3E-28 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 BWK49_RS19775 6fcf0df8a061cc77bb150cff79d21df2 309 PRINTS PR00409 Phthalate dioxygenase reductase family signature 51 65 5.3E-28 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 BWK49_RS19775 6fcf0df8a061cc77bb150cff79d21df2 309 PRINTS PR00409 Phthalate dioxygenase reductase family signature 29 39 5.3E-28 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 BWK49_RS19775 6fcf0df8a061cc77bb150cff79d21df2 309 PRINTS PR00409 Phthalate dioxygenase reductase family signature 75 89 5.3E-28 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 BWK49_RS19775 6fcf0df8a061cc77bb150cff79d21df2 309 Pfam PF00970 Oxidoreductase FAD-binding domain 7 101 4.8E-5 T 06-07-2017 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 BWK49_RS19775 6fcf0df8a061cc77bb150cff79d21df2 309 SUPERFAMILY SSF52343 97 223 4.45E-22 T 06-07-2017 BWK49_RS19775 6fcf0df8a061cc77bb150cff79d21df2 309 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 263 271 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 BWK49_RS19775 6fcf0df8a061cc77bb150cff79d21df2 309 SUPERFAMILY SSF63380 3 99 1.45E-26 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 BWK49_RS19775 6fcf0df8a061cc77bb150cff79d21df2 309 SUPERFAMILY SSF54292 212 307 6.69E-21 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 BWK49_RS19775 6fcf0df8a061cc77bb150cff79d21df2 309 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 236 300 3.0E-10 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 BWK49_RS19775 6fcf0df8a061cc77bb150cff79d21df2 309 Gene3D G3DSA:3.40.50.80 105 215 4.1E-20 T 06-07-2017 BWK49_RS15750 d80ce8c473097f72f5ae2269113886f1 92 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 41 49 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 BWK49_RS15750 d80ce8c473097f72f5ae2269113886f1 92 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 10 83 4.4E-15 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 BWK49_RS15750 d80ce8c473097f72f5ae2269113886f1 92 SUPERFAMILY SSF54292 6 92 6.03E-26 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 BWK49_RS15750 d80ce8c473097f72f5ae2269113886f1 92 Gene3D G3DSA:3.10.20.30 5 88 2.5E-26 T 06-07-2017 IPR012675 Beta-grasp domain BWK49_RS09515 90d7e7fd831bbbb16d9aa0ec5cab33dc 359 SUPERFAMILY SSF47203 210 355 4.19E-31 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS09515 90d7e7fd831bbbb16d9aa0ec5cab33dc 359 Gene3D G3DSA:1.10.540.10 1 101 5.0E-15 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS09515 90d7e7fd831bbbb16d9aa0ec5cab33dc 359 SUPERFAMILY SSF56645 1 181 3.38E-18 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS09515 90d7e7fd831bbbb16d9aa0ec5cab33dc 359 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 217 334 2.7E-21 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS09515 90d7e7fd831bbbb16d9aa0ec5cab33dc 359 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 96 3.0E-10 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS09515 90d7e7fd831bbbb16d9aa0ec5cab33dc 359 Gene3D G3DSA:1.20.140.10 212 354 1.2E-28 T 06-07-2017 BWK49_RS13930 e9f6a6545b94e6050e3facad4c7cac25 536 SUPERFAMILY SSF140459 5 177 7.59E-59 T 06-07-2017 BWK49_RS13930 e9f6a6545b94e6050e3facad4c7cac25 536 Pfam PF00823 PPE family 8 164 5.7E-59 T 06-07-2017 IPR000030 PPE family BWK49_RS12155 25357c94b22e1081c33caa000a6a15b6 418 Gene3D G3DSA:1.10.630.10 38 417 4.2E-116 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS12155 25357c94b22e1081c33caa000a6a15b6 418 SUPERFAMILY SSF48264 35 417 5.5E-93 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS12155 25357c94b22e1081c33caa000a6a15b6 418 PRINTS PR00385 P450 superfamily signature 259 276 3.3E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS12155 25357c94b22e1081c33caa000a6a15b6 418 PRINTS PR00385 P450 superfamily signature 370 381 3.3E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS12155 25357c94b22e1081c33caa000a6a15b6 418 PRINTS PR00385 P450 superfamily signature 294 305 3.3E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS12155 25357c94b22e1081c33caa000a6a15b6 418 Pfam PF00067 Cytochrome P450 293 386 9.2E-18 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS12155 25357c94b22e1081c33caa000a6a15b6 418 Pfam PF00067 Cytochrome P450 65 283 3.7E-9 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS12155 25357c94b22e1081c33caa000a6a15b6 418 PRINTS PR00359 B-class P450 signature 151 167 1.6E-42 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS12155 25357c94b22e1081c33caa000a6a15b6 418 PRINTS PR00359 B-class P450 signature 168 183 1.6E-42 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS12155 25357c94b22e1081c33caa000a6a15b6 418 PRINTS PR00359 B-class P450 signature 339 354 1.6E-42 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS12155 25357c94b22e1081c33caa000a6a15b6 418 PRINTS PR00359 B-class P450 signature 311 338 1.6E-42 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS12155 25357c94b22e1081c33caa000a6a15b6 418 PRINTS PR00359 B-class P450 signature 105 116 1.6E-42 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS12155 25357c94b22e1081c33caa000a6a15b6 418 PRINTS PR00359 B-class P450 signature 370 381 1.6E-42 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS12155 25357c94b22e1081c33caa000a6a15b6 418 PRINTS PR00359 B-class P450 signature 294 305 1.6E-42 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS12155 25357c94b22e1081c33caa000a6a15b6 418 PRINTS PR00359 B-class P450 signature 212 234 1.6E-42 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS12155 25357c94b22e1081c33caa000a6a15b6 418 PRINTS PR00359 B-class P450 signature 361 370 1.6E-42 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS12435 4eba506d232e0bffcf9a00ab4c01db8f 143 Gene3D G3DSA:3.40.140.10 2 130 7.9E-31 T 06-07-2017 BWK49_RS12435 4eba506d232e0bffcf9a00ab4c01db8f 143 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 2 93 1.4E-14 T 06-07-2017 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 BWK49_RS12435 4eba506d232e0bffcf9a00ab4c01db8f 143 SUPERFAMILY SSF53927 2 139 4.35E-33 T 06-07-2017 IPR016193 Cytidine deaminase-like GO:0003824 BWK49_RS07165 acc41e3d52bc399b7aa669a87da31cc2 244 SMART SM00345 15 74 9.3E-21 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 BWK49_RS07165 acc41e3d52bc399b7aa669a87da31cc2 244 SUPERFAMILY SSF46785 5 78 4.78E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS07165 acc41e3d52bc399b7aa669a87da31cc2 244 Pfam PF07729 FCD domain 108 227 3.1E-10 T 06-07-2017 IPR011711 GntR, C-terminal BWK49_RS07165 acc41e3d52bc399b7aa669a87da31cc2 244 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 74 2.3E-21 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 BWK49_RS07165 acc41e3d52bc399b7aa669a87da31cc2 244 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 1.1E-10 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 BWK49_RS07165 acc41e3d52bc399b7aa669a87da31cc2 244 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 1.1E-10 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 BWK49_RS07165 acc41e3d52bc399b7aa669a87da31cc2 244 SUPERFAMILY SSF48008 105 236 3.66E-10 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal BWK49_RS07165 acc41e3d52bc399b7aa669a87da31cc2 244 SMART SM00895 107 228 7.3E-8 T 06-07-2017 IPR011711 GntR, C-terminal BWK49_RS07165 acc41e3d52bc399b7aa669a87da31cc2 244 Gene3D G3DSA:1.20.120.530 102 237 2.4E-10 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal BWK49_RS07165 acc41e3d52bc399b7aa669a87da31cc2 244 Gene3D G3DSA:1.10.10.10 7 77 2.9E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS14015 b099de8a2195f59ecff7e46f06126ffb 217 Pfam PF04945 YHS domain 170 214 3.5E-12 T 06-07-2017 IPR007029 YHS domain BWK49_RS14015 b099de8a2195f59ecff7e46f06126ffb 217 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 9 149 2.6E-7 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 BWK49_RS14015 b099de8a2195f59ecff7e46f06126ffb 217 SMART SM00746 172 210 0.0028 T 06-07-2017 IPR011017 TRASH domain BWK49_RS14015 b099de8a2195f59ecff7e46f06126ffb 217 SUPERFAMILY SSF55073 5 161 1.57E-25 T 06-07-2017 IPR029787 Nucleotide cyclase BWK49_RS14015 b099de8a2195f59ecff7e46f06126ffb 217 Gene3D G3DSA:3.30.70.1230 7 161 4.0E-13 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 BWK49_RS14015 b099de8a2195f59ecff7e46f06126ffb 217 SUPERFAMILY SSF47240 166 214 9.73E-7 T 06-07-2017 IPR009078 Ferritin-like superfamily BWK49_RS22755 c227722c8ff14f31a1b0dedda950f307 71 Pfam PF00364 Biotin-requiring enzyme 10 70 1.2E-15 T 06-07-2017 IPR000089 Biotin/lipoyl attachment BWK49_RS22755 c227722c8ff14f31a1b0dedda950f307 71 Gene3D G3DSA:2.40.50.100 3 70 9.2E-19 T 06-07-2017 BWK49_RS22755 c227722c8ff14f31a1b0dedda950f307 71 SUPERFAMILY SSF51230 5 70 6.54E-18 T 06-07-2017 IPR011053 Single hybrid motif BWK49_RS18785 e16a65c2b35a94a387ad15366a432986 548 Gene3D G3DSA:3.40.190.10 222 325 2.7E-13 T 06-07-2017 BWK49_RS18785 e16a65c2b35a94a387ad15366a432986 548 Gene3D G3DSA:3.10.105.10 326 513 7.1E-18 T 06-07-2017 BWK49_RS18785 e16a65c2b35a94a387ad15366a432986 548 Gene3D G3DSA:3.90.76.10 90 182 6.3E-7 T 06-07-2017 BWK49_RS18785 e16a65c2b35a94a387ad15366a432986 548 SUPERFAMILY SSF53850 219 544 1.61E-48 T 06-07-2017 BWK49_RS18785 e16a65c2b35a94a387ad15366a432986 548 SUPERFAMILY SSF53850 32 188 1.61E-48 T 06-07-2017 BWK49_RS18785 e16a65c2b35a94a387ad15366a432986 548 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 91 443 1.2E-15 T 06-07-2017 IPR000914 Solute-binding protein family 5 domain BWK49_RS03315 3b751e26218276ef568d6dc93eb89966 514 Pfam PF13193 AMP-binding enzyme C-terminal domain 429 504 6.9E-19 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS03315 3b751e26218276ef568d6dc93eb89966 514 Pfam PF00501 AMP-binding enzyme 13 419 1.5E-95 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS03315 3b751e26218276ef568d6dc93eb89966 514 Gene3D G3DSA:3.40.50.980 6 180 3.8E-34 T 06-07-2017 BWK49_RS03315 3b751e26218276ef568d6dc93eb89966 514 Gene3D G3DSA:2.30.38.10 345 411 5.7E-22 T 06-07-2017 BWK49_RS03315 3b751e26218276ef568d6dc93eb89966 514 Gene3D G3DSA:3.30.300.30 415 513 2.7E-29 T 06-07-2017 BWK49_RS03315 3b751e26218276ef568d6dc93eb89966 514 ProSitePatterns PS00455 Putative AMP-binding domain signature. 176 187 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS03315 3b751e26218276ef568d6dc93eb89966 514 SUPERFAMILY SSF56801 5 513 8.77E-146 T 06-07-2017 BWK49_RS03315 3b751e26218276ef568d6dc93eb89966 514 Gene3D G3DSA:3.40.50.980 181 344 1.7E-42 T 06-07-2017 BWK49_RS27005 330427a80bb84aaee8bdc9568ec3580f 396 SUPERFAMILY SSF89796 169 353 2.49E-32 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS27005 330427a80bb84aaee8bdc9568ec3580f 396 Gene3D G3DSA:3.40.50.10540 169 352 5.6E-41 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS27005 330427a80bb84aaee8bdc9568ec3580f 396 Pfam PF02515 CoA-transferase family III 170 347 1.7E-28 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 BWK49_RS27005 330427a80bb84aaee8bdc9568ec3580f 396 SUPERFAMILY SSF89796 8 154 9.16E-5 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS12985 78b2a13b21069f39f7e31a42d1ac608c 462 SUPERFAMILY SSF51569 6 461 3.37E-190 T 06-07-2017 BWK49_RS12985 78b2a13b21069f39f7e31a42d1ac608c 462 TIGRFAM TIGR01358 DAHP_synth_II: 3-deoxy-7-phosphoheptulonate synthase 26 462 5.2E-222 T 06-07-2017 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 BWK49_RS12985 78b2a13b21069f39f7e31a42d1ac608c 462 Pfam PF01474 Class-II DAHP synthetase family 31 457 2.1E-186 T 06-07-2017 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 BWK49_RS01135 ccd746c962a8884b6790adbb8d77ccf1 628 Gene3D G3DSA:3.90.550.10 160 417 7.6E-12 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases BWK49_RS01135 ccd746c962a8884b6790adbb8d77ccf1 628 Pfam PF13641 Glycosyltransferase like family 2 160 418 4.3E-51 T 06-07-2017 BWK49_RS01135 ccd746c962a8884b6790adbb8d77ccf1 628 SUPERFAMILY SSF53448 333 423 7.22E-27 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases BWK49_RS01135 ccd746c962a8884b6790adbb8d77ccf1 628 SUPERFAMILY SSF53448 158 296 7.22E-27 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases BWK49_RS01725 31355a00179e6dc3a41fa530cfbe24f8 330 Pfam PF13011 leucine-zipper of insertion element IS481 2 81 2.7E-19 T 06-07-2017 IPR024967 DNA-binding domain, IS481-type BWK49_RS01725 31355a00179e6dc3a41fa530cfbe24f8 330 Gene3D G3DSA:3.30.420.10 127 273 1.2E-31 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS01725 31355a00179e6dc3a41fa530cfbe24f8 330 SUPERFAMILY SSF53098 183 274 1.52E-23 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS01725 31355a00179e6dc3a41fa530cfbe24f8 330 SUPERFAMILY SSF53098 133 145 1.52E-23 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS01725 31355a00179e6dc3a41fa530cfbe24f8 330 Pfam PF00665 Integrase core domain 131 273 1.7E-36 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 BWK49_RS01725 31355a00179e6dc3a41fa530cfbe24f8 330 SUPERFAMILY SSF46689 10 108 1.67E-7 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS17070 55d6e2c151754b4268cb844adb3575fe 972 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 5 935 0.0 T 06-07-2017 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 BWK49_RS17070 55d6e2c151754b4268cb844adb3575fe 972 Pfam PF00005 ABC transporter 634 870 4.5E-9 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 BWK49_RS17070 55d6e2c151754b4268cb844adb3575fe 972 Gene3D G3DSA:3.30.1490.20 201 242 1.3E-28 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 BWK49_RS17070 55d6e2c151754b4268cb844adb3575fe 972 Gene3D G3DSA:3.30.1490.20 131 154 1.3E-28 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 BWK49_RS17070 55d6e2c151754b4268cb844adb3575fe 972 Gene3D G3DSA:3.40.50.300 7 90 7.8E-54 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS17070 55d6e2c151754b4268cb844adb3575fe 972 Gene3D G3DSA:3.40.50.300 831 949 4.6E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS17070 55d6e2c151754b4268cb844adb3575fe 972 Gene3D G3DSA:3.40.50.300 622 683 4.6E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS17070 55d6e2c151754b4268cb844adb3575fe 972 Gene3D G3DSA:3.40.50.300 489 608 7.8E-54 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS17070 55d6e2c151754b4268cb844adb3575fe 972 ProSitePatterns PS00211 ABC transporters family signature. 840 854 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 BWK49_RS17070 55d6e2c151754b4268cb844adb3575fe 972 ProSitePatterns PS00211 ABC transporters family signature. 498 512 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 BWK49_RS17070 55d6e2c151754b4268cb844adb3575fe 972 Gene3D G3DSA:1.20.1580.10 704 830 3.5E-55 T 06-07-2017 BWK49_RS17070 55d6e2c151754b4268cb844adb3575fe 972 SUPERFAMILY SSF52540 625 924 1.93E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS17070 55d6e2c151754b4268cb844adb3575fe 972 Hamap MF_00205 UvrABC system protein A [uvrA]. 2 950 23.057 T 06-07-2017 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 BWK49_RS17070 55d6e2c151754b4268cb844adb3575fe 972 Gene3D G3DSA:1.20.1580.10 255 289 8.2E-51 T 06-07-2017 BWK49_RS17070 55d6e2c151754b4268cb844adb3575fe 972 Gene3D G3DSA:1.20.1580.10 413 488 8.2E-51 T 06-07-2017 BWK49_RS17070 55d6e2c151754b4268cb844adb3575fe 972 Gene3D G3DSA:1.20.1580.10 92 130 8.2E-51 T 06-07-2017 BWK49_RS17070 55d6e2c151754b4268cb844adb3575fe 972 SUPERFAMILY SSF52540 441 580 1.15E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS17070 55d6e2c151754b4268cb844adb3575fe 972 SUPERFAMILY SSF52540 11 205 1.15E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS17070 55d6e2c151754b4268cb844adb3575fe 972 Gene3D G3DSA:1.10.8.280 292 412 6.4E-41 T 06-07-2017 BWK49_RS08055 f356e12656ab539b56c6afa771b95739 426 SUPERFAMILY SSF48498 94 205 1.37E-7 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS08055 f356e12656ab539b56c6afa771b95739 426 Gene3D G3DSA:1.10.357.10 15 206 5.4E-31 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS08055 f356e12656ab539b56c6afa771b95739 426 Gene3D G3DSA:1.10.10.60 239 287 1.6E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS08055 f356e12656ab539b56c6afa771b95739 426 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 67 7.2E-13 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS08055 f356e12656ab539b56c6afa771b95739 426 Pfam PF00440 Bacterial regulatory proteins, tetR family 247 290 3.0E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS08055 f356e12656ab539b56c6afa771b95739 426 SUPERFAMILY SSF46689 13 87 3.34E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS08055 f356e12656ab539b56c6afa771b95739 426 Gene3D G3DSA:1.10.357.10 288 393 3.0E-9 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS08055 f356e12656ab539b56c6afa771b95739 426 SUPERFAMILY SSF46689 238 317 1.44E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS08055 f356e12656ab539b56c6afa771b95739 426 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 35 2.6E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS08055 f356e12656ab539b56c6afa771b95739 426 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 2.6E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS18960 a9fd5386d2ed7ddc6464d5b78f88acbe 317 Gene3D G3DSA:3.20.20.70 2 297 9.2E-47 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 BWK49_RS18960 a9fd5386d2ed7ddc6464d5b78f88acbe 317 Pfam PF03060 Nitronate monooxygenase 11 61 3.5E-8 T 06-07-2017 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 BWK49_RS18960 a9fd5386d2ed7ddc6464d5b78f88acbe 317 Pfam PF03060 Nitronate monooxygenase 84 302 1.1E-31 T 06-07-2017 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 BWK49_RS18960 a9fd5386d2ed7ddc6464d5b78f88acbe 317 SUPERFAMILY SSF51412 2 299 6.87E-47 T 06-07-2017 BWK49_RS27720 8e6a5a92d25d3f1dc43098ac333600c6 548 Pfam PF13193 AMP-binding enzyme C-terminal domain 442 515 6.1E-17 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS27720 8e6a5a92d25d3f1dc43098ac333600c6 548 Pfam PF00501 AMP-binding enzyme 24 432 1.3E-79 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS27720 8e6a5a92d25d3f1dc43098ac333600c6 548 Gene3D G3DSA:2.30.38.10 358 426 1.2E-19 T 06-07-2017 BWK49_RS27720 8e6a5a92d25d3f1dc43098ac333600c6 548 Gene3D G3DSA:3.40.50.980 19 183 8.2E-28 T 06-07-2017 BWK49_RS27720 8e6a5a92d25d3f1dc43098ac333600c6 548 Gene3D G3DSA:3.40.50.980 184 340 3.7E-33 T 06-07-2017 BWK49_RS27720 8e6a5a92d25d3f1dc43098ac333600c6 548 SUPERFAMILY SSF56801 19 527 9.94E-123 T 06-07-2017 BWK49_RS27720 8e6a5a92d25d3f1dc43098ac333600c6 548 Gene3D G3DSA:3.30.300.30 427 525 1.1E-27 T 06-07-2017 BWK49_RS27720 8e6a5a92d25d3f1dc43098ac333600c6 548 ProSitePatterns PS00455 Putative AMP-binding domain signature. 178 189 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS12095 5a6294512d2a164f78597f73b32fa62e 324 SUPERFAMILY SSF51679 16 320 9.29E-46 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS12095 5a6294512d2a164f78597f73b32fa62e 324 Gene3D G3DSA:3.20.20.30 9 321 3.9E-54 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS12095 5a6294512d2a164f78597f73b32fa62e 324 Pfam PF00296 Luciferase-like monooxygenase 19 251 4.2E-32 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS28015 4efbf33550f2fa552728167c905f0008 156 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 12 153 1.4E-10 T 06-07-2017 IPR019587 Polyketide cyclase/dehydrase BWK49_RS28015 4efbf33550f2fa552728167c905f0008 156 SUPERFAMILY SSF55961 3 154 4.89E-21 T 06-07-2017 BWK49_RS28015 4efbf33550f2fa552728167c905f0008 156 Gene3D G3DSA:3.30.530.20 9 155 5.6E-10 T 06-07-2017 IPR023393 START-like domain BWK49_RS22070 dda39902cd600e17081f46f96798af37 325 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 42 171 1.5E-63 T 06-07-2017 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 BWK49_RS22070 dda39902cd600e17081f46f96798af37 325 Gene3D G3DSA:1.10.8.300 204 310 3.0E-35 T 06-07-2017 BWK49_RS22070 dda39902cd600e17081f46f96798af37 325 PIRSF PIRSF002849 2 317 4.8E-129 T 06-07-2017 IPR016366 ATPase chaperone, AAA-type, MoxR, predicted BWK49_RS22070 dda39902cd600e17081f46f96798af37 325 SUPERFAMILY SSF52540 13 292 1.09E-45 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS22070 dda39902cd600e17081f46f96798af37 325 Gene3D G3DSA:3.40.50.300 24 188 1.5E-42 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS04740 9157a12a63a5c3e3c64d297b2a70e82a 515 SUPERFAMILY SSF56801 10 508 1.15E-161 T 06-07-2017 BWK49_RS04740 9157a12a63a5c3e3c64d297b2a70e82a 515 Gene3D G3DSA:3.30.300.30 407 503 1.5E-33 T 06-07-2017 BWK49_RS04740 9157a12a63a5c3e3c64d297b2a70e82a 515 Pfam PF13193 AMP-binding enzyme C-terminal domain 421 496 2.6E-24 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS04740 9157a12a63a5c3e3c64d297b2a70e82a 515 Pfam PF00501 AMP-binding enzyme 17 412 4.9E-110 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS04740 9157a12a63a5c3e3c64d297b2a70e82a 515 Gene3D G3DSA:3.40.50.980 172 331 3.8E-42 T 06-07-2017 BWK49_RS04740 9157a12a63a5c3e3c64d297b2a70e82a 515 Gene3D G3DSA:3.40.50.980 14 171 2.7E-42 T 06-07-2017 BWK49_RS04740 9157a12a63a5c3e3c64d297b2a70e82a 515 ProSitePatterns PS00455 Putative AMP-binding domain signature. 166 177 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS04740 9157a12a63a5c3e3c64d297b2a70e82a 515 Gene3D G3DSA:2.30.38.10 332 403 1.1E-28 T 06-07-2017 BWK49_RS15680 a9453ff133e64bcf923310c69504cc19 392 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 121 4.6E-22 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS15680 a9453ff133e64bcf923310c69504cc19 392 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 230 383 2.1E-37 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS15680 a9453ff133e64bcf923310c69504cc19 392 Gene3D G3DSA:2.40.110.10 125 219 2.3E-34 T 06-07-2017 BWK49_RS15680 a9453ff133e64bcf923310c69504cc19 392 SUPERFAMILY SSF47203 230 388 1.93E-27 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS15680 a9453ff133e64bcf923310c69504cc19 392 Gene3D G3DSA:1.10.540.10 1 123 5.9E-24 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS15680 a9453ff133e64bcf923310c69504cc19 392 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 125 218 3.2E-20 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 BWK49_RS15680 a9453ff133e64bcf923310c69504cc19 392 SUPERFAMILY SSF56645 1 241 7.2E-70 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS15680 a9453ff133e64bcf923310c69504cc19 392 Gene3D G3DSA:1.20.140.10 220 388 5.6E-37 T 06-07-2017 BWK49_RS27525 2144a4315999ac1f7c1bbed5ccbe705e 168 Pfam PF12680 SnoaL-like domain 24 123 4.4E-9 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain BWK49_RS27525 2144a4315999ac1f7c1bbed5ccbe705e 168 Gene3D G3DSA:3.10.450.50 14 139 1.7E-15 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS27525 2144a4315999ac1f7c1bbed5ccbe705e 168 SUPERFAMILY SSF54427 5 137 4.79E-22 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS17325 ebf151232fbd164f6b49aaa76da4b393 210 Gene3D G3DSA:3.30.230.40 99 210 7.7E-31 T 06-07-2017 BWK49_RS17325 ebf151232fbd164f6b49aaa76da4b393 210 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 70 83 - T 06-07-2017 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 BWK49_RS17325 ebf151232fbd164f6b49aaa76da4b393 210 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 40 190 1.2E-57 T 06-07-2017 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 BWK49_RS17325 ebf151232fbd164f6b49aaa76da4b393 210 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 11 210 41.613 T 06-07-2017 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 BWK49_RS17325 ebf151232fbd164f6b49aaa76da4b393 210 SUPERFAMILY SSF54211 11 95 8.6E-31 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold BWK49_RS17325 ebf151232fbd164f6b49aaa76da4b393 210 Gene3D G3DSA:3.30.230.40 11 98 4.8E-35 T 06-07-2017 BWK49_RS17325 ebf151232fbd164f6b49aaa76da4b393 210 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 172 184 - T 06-07-2017 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 BWK49_RS17325 ebf151232fbd164f6b49aaa76da4b393 210 SUPERFAMILY SSF54211 96 195 2.17E-28 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold BWK49_RS17150 ae72c2f1459ec99fb7d148b96d82a72c 261 SMART SM01232 131 220 9.4E-23 T 06-07-2017 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 BWK49_RS17150 ae72c2f1459ec99fb7d148b96d82a72c 261 SUPERFAMILY SSF57716 210 261 4.56E-12 T 06-07-2017 BWK49_RS17150 ae72c2f1459ec99fb7d148b96d82a72c 261 SMART SM00898 2 116 6.9E-26 T 06-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 BWK49_RS17150 ae72c2f1459ec99fb7d148b96d82a72c 261 Gene3D G3DSA:1.10.8.50 132 261 1.6E-29 T 06-07-2017 BWK49_RS17150 ae72c2f1459ec99fb7d148b96d82a72c 261 ProSitePatterns PS01242 Zinc finger FPG-type signature. 236 260 - T 06-07-2017 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 BWK49_RS17150 ae72c2f1459ec99fb7d148b96d82a72c 261 SUPERFAMILY SSF81624 2 136 2.35E-25 T 06-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 BWK49_RS17150 ae72c2f1459ec99fb7d148b96d82a72c 261 SUPERFAMILY SSF46946 132 216 1.62E-18 T 06-07-2017 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 BWK49_RS17150 ae72c2f1459ec99fb7d148b96d82a72c 261 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 151 215 1.4E-15 T 06-07-2017 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 BWK49_RS17150 ae72c2f1459ec99fb7d148b96d82a72c 261 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 2 112 8.9E-20 T 06-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 BWK49_RS17150 ae72c2f1459ec99fb7d148b96d82a72c 261 Gene3D G3DSA:3.20.190.10 2 123 2.6E-25 T 06-07-2017 BWK49_RS17150 ae72c2f1459ec99fb7d148b96d82a72c 261 Pfam PF06827 Zinc finger found in FPG and IleRS 235 261 1.9E-8 T 06-07-2017 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 BWK49_RS19970 a0106936641f1307f9d8a796735cf023 613 Gene3D G3DSA:3.40.50.410 436 573 4.1E-12 T 06-07-2017 IPR002035 von Willebrand factor, type A BWK49_RS19970 a0106936641f1307f9d8a796735cf023 613 Gene3D G3DSA:1.10.8.80 218 304 1.9E-33 T 06-07-2017 BWK49_RS19970 a0106936641f1307f9d8a796735cf023 613 Gene3D G3DSA:3.40.50.300 2 170 9.7E-49 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS19970 a0106936641f1307f9d8a796735cf023 613 SMART SM00382 27 175 2.3E-4 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS19970 a0106936641f1307f9d8a796735cf023 613 SMART SM00327 433 606 1.6E-23 T 06-07-2017 IPR002035 von Willebrand factor, type A BWK49_RS19970 a0106936641f1307f9d8a796735cf023 613 Pfam PF13519 von Willebrand factor type A domain 436 542 1.6E-14 T 06-07-2017 IPR002035 von Willebrand factor, type A BWK49_RS19970 a0106936641f1307f9d8a796735cf023 613 SUPERFAMILY SSF52540 2 296 2.95E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS19970 a0106936641f1307f9d8a796735cf023 613 SUPERFAMILY SSF53300 436 592 2.52E-21 T 06-07-2017 IPR002035 von Willebrand factor, type A BWK49_RS19970 a0106936641f1307f9d8a796735cf023 613 Pfam PF07728 AAA domain (dynein-related subfamily) 32 165 6.0E-13 T 06-07-2017 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 BWK49_RS15890 5b9a7484e40070e24f7ae0c50a51e247 229 SUPERFAMILY SSF46785 23 192 4.06E-32 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS15890 5b9a7484e40070e24f7ae0c50a51e247 229 Gene3D G3DSA:1.10.10.10 23 104 3.9E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS15890 5b9a7484e40070e24f7ae0c50a51e247 229 Pfam PF03551 Transcriptional regulator PadR-like family 25 97 3.5E-11 T 06-07-2017 IPR005149 Transcription regulator PadR, N-terminal BWK49_RS02690 15f4e9b0f7b32085b3f780ed75f0186a 129 Pfam PF01740 STAS domain 8 101 2.2E-11 T 06-07-2017 IPR002645 STAS domain BWK49_RS02690 15f4e9b0f7b32085b3f780ed75f0186a 129 SUPERFAMILY SSF52091 1 113 5.3E-17 T 06-07-2017 IPR002645 STAS domain BWK49_RS02690 15f4e9b0f7b32085b3f780ed75f0186a 129 Gene3D G3DSA:3.30.750.24 3 95 2.5E-13 T 06-07-2017 IPR002645 STAS domain BWK49_RS26170 3a3422a6d8b84c0aa17286a2f31c9dae 986 Pfam PF02754 Cysteine-rich domain 484 575 2.2E-16 T 06-07-2017 IPR004017 Cysteine-rich domain BWK49_RS26170 3a3422a6d8b84c0aa17286a2f31c9dae 986 Pfam PF02754 Cysteine-rich domain 614 700 1.5E-17 T 06-07-2017 IPR004017 Cysteine-rich domain BWK49_RS26170 3a3422a6d8b84c0aa17286a2f31c9dae 986 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 399 410 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site BWK49_RS26170 3a3422a6d8b84c0aa17286a2f31c9dae 986 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 291 302 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site BWK49_RS26170 3a3422a6d8b84c0aa17286a2f31c9dae 986 SUPERFAMILY SSF46548 275 312 8.11E-20 T 06-07-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 BWK49_RS26170 3a3422a6d8b84c0aa17286a2f31c9dae 986 SUPERFAMILY SSF46548 372 428 8.11E-20 T 06-07-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 BWK49_RS26170 3a3422a6d8b84c0aa17286a2f31c9dae 986 Gene3D G3DSA:3.30.70.20 665 695 1.3E-4 T 06-07-2017 BWK49_RS26170 3a3422a6d8b84c0aa17286a2f31c9dae 986 Gene3D G3DSA:1.10.1060.10 267 323 8.6E-31 T 06-07-2017 BWK49_RS26170 3a3422a6d8b84c0aa17286a2f31c9dae 986 Gene3D G3DSA:1.10.1060.10 377 429 8.6E-31 T 06-07-2017 BWK49_RS26170 3a3422a6d8b84c0aa17286a2f31c9dae 986 Pfam PF13183 4Fe-4S dicluster domain 288 413 4.4E-11 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain BWK49_RS25735 3ff97f3d3066165bda899a4643b0fb66 197 SUPERFAMILY SSF56420 3 188 1.15E-48 T 06-07-2017 IPR023635 Peptide deformylase BWK49_RS25735 3ff97f3d3066165bda899a4643b0fb66 197 Pfam PF01327 Polypeptide deformylase 5 163 2.5E-37 T 06-07-2017 IPR023635 Peptide deformylase BWK49_RS25735 3ff97f3d3066165bda899a4643b0fb66 197 PIRSF PIRSF004749 1 183 2.4E-37 T 06-07-2017 IPR023635 Peptide deformylase BWK49_RS25735 3ff97f3d3066165bda899a4643b0fb66 197 Gene3D G3DSA:3.90.45.10 5 192 9.3E-55 T 06-07-2017 IPR023635 Peptide deformylase BWK49_RS25735 3ff97f3d3066165bda899a4643b0fb66 197 PRINTS PR01576 Peptide deformylase signature 38 67 1.9E-29 T 06-07-2017 IPR023635 Peptide deformylase BWK49_RS25735 3ff97f3d3066165bda899a4643b0fb66 197 PRINTS PR01576 Peptide deformylase signature 116 134 1.9E-29 T 06-07-2017 IPR023635 Peptide deformylase BWK49_RS25735 3ff97f3d3066165bda899a4643b0fb66 197 PRINTS PR01576 Peptide deformylase signature 104 115 1.9E-29 T 06-07-2017 IPR023635 Peptide deformylase BWK49_RS25735 3ff97f3d3066165bda899a4643b0fb66 197 PRINTS PR01576 Peptide deformylase signature 135 164 1.9E-29 T 06-07-2017 IPR023635 Peptide deformylase BWK49_RS25735 3ff97f3d3066165bda899a4643b0fb66 197 Hamap MF_00163 Peptide deformylase [def]. 2 177 26.47 T 06-07-2017 IPR023635 Peptide deformylase BWK49_RS10570 2963cea5e70768524daa42b0457bfaa3 615 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 76 101 1.7E-31 T 06-07-2017 BWK49_RS10570 2963cea5e70768524daa42b0457bfaa3 615 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 210 231 1.7E-31 T 06-07-2017 BWK49_RS10570 2963cea5e70768524daa42b0457bfaa3 615 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 300 312 1.7E-31 T 06-07-2017 BWK49_RS10570 2963cea5e70768524daa42b0457bfaa3 615 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 400 419 1.7E-31 T 06-07-2017 BWK49_RS10570 2963cea5e70768524daa42b0457bfaa3 615 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 149 170 1.7E-31 T 06-07-2017 BWK49_RS10570 2963cea5e70768524daa42b0457bfaa3 615 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 232 258 1.7E-31 T 06-07-2017 BWK49_RS10570 2963cea5e70768524daa42b0457bfaa3 615 Pfam PF00361 Proton-conducting membrane transporter 128 405 3.7E-49 T 06-07-2017 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS06935 fcb638670775120047de3a7b974f4431 259 SUPERFAMILY SSF53790 16 255 7.72E-36 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 BWK49_RS06935 fcb638670775120047de3a7b974f4431 259 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 16 231 2.3E-29 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 BWK49_RS06935 fcb638670775120047de3a7b974f4431 259 PIRSF PIRSF036525 14 259 7.1E-103 T 06-07-2017 IPR012797 Cobalamin (vitamin B12) biosynthesis CobF, precorrin-6A synthase GO:0009236|GO:0043819 KEGG: 00860+2.1.1.152|MetaCyc: PWY-7376 BWK49_RS06935 fcb638670775120047de3a7b974f4431 259 Gene3D G3DSA:3.30.950.10 154 257 7.7E-45 T 06-07-2017 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 BWK49_RS06935 fcb638670775120047de3a7b974f4431 259 Gene3D G3DSA:3.40.1010.10 15 153 1.1E-39 T 06-07-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 BWK49_RS06935 fcb638670775120047de3a7b974f4431 259 TIGRFAM TIGR02434 CobF: precorrin-6A synthase (deacetylating) 15 256 1.6E-110 T 06-07-2017 IPR012797 Cobalamin (vitamin B12) biosynthesis CobF, precorrin-6A synthase GO:0009236|GO:0043819 KEGG: 00860+2.1.1.152|MetaCyc: PWY-7376 BWK49_RS05930 7ef090efbebf1d43ff5655e5fdcf5cb2 330 Gene3D G3DSA:3.50.30.50 107 329 8.3E-29 T 06-07-2017 BWK49_RS05930 7ef090efbebf1d43ff5655e5fdcf5cb2 330 Pfam PF04199 Putative cyclase 104 261 4.2E-23 T 06-07-2017 IPR007325 Kynurenine formamidase GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734 BWK49_RS05930 7ef090efbebf1d43ff5655e5fdcf5cb2 330 SUPERFAMILY SSF102198 97 329 1.7E-25 T 06-07-2017 BWK49_RS27585 954f8e0604a0c873e6f9049f6596e803 364 SUPERFAMILY SSF54292 263 364 2.62E-15 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 BWK49_RS27585 954f8e0604a0c873e6f9049f6596e803 364 Pfam PF00970 Oxidoreductase FAD-binding domain 80 150 3.5E-10 T 06-07-2017 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 BWK49_RS27585 954f8e0604a0c873e6f9049f6596e803 364 Gene3D G3DSA:3.10.20.30 264 362 5.4E-17 T 06-07-2017 IPR012675 Beta-grasp domain BWK49_RS27585 954f8e0604a0c873e6f9049f6596e803 364 PRINTS PR00410 Phenol hydroxylase reductase family signature 83 95 3.2E-9 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 BWK49_RS27585 954f8e0604a0c873e6f9049f6596e803 364 PRINTS PR00410 Phenol hydroxylase reductase family signature 161 180 3.2E-9 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 BWK49_RS27585 954f8e0604a0c873e6f9049f6596e803 364 PRINTS PR00410 Phenol hydroxylase reductase family signature 244 252 3.2E-9 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 BWK49_RS27585 954f8e0604a0c873e6f9049f6596e803 364 Gene3D G3DSA:3.40.50.80 142 263 2.5E-24 T 06-07-2017 BWK49_RS27585 954f8e0604a0c873e6f9049f6596e803 364 SUPERFAMILY SSF52343 148 274 3.14E-26 T 06-07-2017 BWK49_RS27585 954f8e0604a0c873e6f9049f6596e803 364 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 292 335 4.8E-5 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 BWK49_RS27585 954f8e0604a0c873e6f9049f6596e803 364 Gene3D G3DSA:2.40.30.10 40 141 2.8E-21 T 06-07-2017 BWK49_RS27585 954f8e0604a0c873e6f9049f6596e803 364 Pfam PF00175 Oxidoreductase NAD-binding domain 162 258 7.9E-9 T 06-07-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 BWK49_RS27585 954f8e0604a0c873e6f9049f6596e803 364 SUPERFAMILY SSF63380 52 152 1.18E-21 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 BWK49_RS23190 dc5b3cba1c34bc0c309107c10a339890 210 Gene3D G3DSA:3.90.950.10 2 201 1.1E-53 T 06-07-2017 IPR029001 Inosine triphosphate pyrophosphatase-like BWK49_RS23190 dc5b3cba1c34bc0c309107c10a339890 210 SUPERFAMILY SSF52972 2 196 4.9E-46 T 06-07-2017 IPR029001 Inosine triphosphate pyrophosphatase-like BWK49_RS23190 dc5b3cba1c34bc0c309107c10a339890 210 Hamap MF_00528 Septum formation protein Maf [maf]. 3 203 26.524 T 06-07-2017 IPR003697 Maf-like protein GO:0005737 BWK49_RS23190 dc5b3cba1c34bc0c309107c10a339890 210 TIGRFAM TIGR00172 maf: septum formation protein Maf 3 196 6.5E-42 T 06-07-2017 IPR003697 Maf-like protein GO:0005737 BWK49_RS23190 dc5b3cba1c34bc0c309107c10a339890 210 Pfam PF02545 Maf-like protein 3 197 1.8E-40 T 06-07-2017 IPR003697 Maf-like protein GO:0005737 BWK49_RS23190 dc5b3cba1c34bc0c309107c10a339890 210 PIRSF PIRSF006305 2 204 1.3E-39 T 06-07-2017 IPR003697 Maf-like protein GO:0005737 BWK49_RS21915 2c65918f81a231e9a6a1e9f98c60fe79 261 Pfam PF00459 Inositol monophosphatase family 7 249 1.5E-48 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 BWK49_RS21915 2c65918f81a231e9a6a1e9f98c60fe79 261 SUPERFAMILY SSF56655 5 258 9.82E-73 T 06-07-2017 BWK49_RS21915 2c65918f81a231e9a6a1e9f98c60fe79 261 Gene3D G3DSA:3.30.540.10 4 154 1.3E-47 T 06-07-2017 BWK49_RS21915 2c65918f81a231e9a6a1e9f98c60fe79 261 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 81 94 - T 06-07-2017 IPR020583 Inositol monophosphatase, metal-binding site BWK49_RS21915 2c65918f81a231e9a6a1e9f98c60fe79 261 PRINTS PR00377 Inositol monophosphatase superfamily signature 81 97 2.5E-19 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 BWK49_RS21915 2c65918f81a231e9a6a1e9f98c60fe79 261 PRINTS PR00377 Inositol monophosphatase superfamily signature 39 59 2.5E-19 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 BWK49_RS21915 2c65918f81a231e9a6a1e9f98c60fe79 261 PRINTS PR00377 Inositol monophosphatase superfamily signature 210 234 2.5E-19 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 BWK49_RS21915 2c65918f81a231e9a6a1e9f98c60fe79 261 PRINTS PR00377 Inositol monophosphatase superfamily signature 61 77 2.5E-19 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 BWK49_RS21915 2c65918f81a231e9a6a1e9f98c60fe79 261 TIGRFAM TIGR02067 his_9_HisN: histidinol-phosphatase 7 258 5.2E-85 T 06-07-2017 IPR011809 Histidinol-phosphate phosphatase, putative, inositol monophosphatase GO:0004401 KEGG: 00340+3.1.3.15 BWK49_RS21915 2c65918f81a231e9a6a1e9f98c60fe79 261 Gene3D G3DSA:3.40.190.80 155 258 5.0E-20 T 06-07-2017 BWK49_RS24180 42008861135095cb6c07ec4e3f62a859 410 SUPERFAMILY SSF50129 19 216 2.93E-35 T 06-07-2017 IPR011032 GroES-like BWK49_RS24180 42008861135095cb6c07ec4e3f62a859 410 Gene3D G3DSA:3.40.50.720 222 372 4.9E-18 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS24180 42008861135095cb6c07ec4e3f62a859 410 Pfam PF00107 Zinc-binding dehydrogenase 218 350 1.8E-13 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 BWK49_RS24180 42008861135095cb6c07ec4e3f62a859 410 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 45 175 3.1E-20 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 BWK49_RS24180 42008861135095cb6c07ec4e3f62a859 410 SUPERFAMILY SSF51735 183 353 1.58E-20 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS24180 42008861135095cb6c07ec4e3f62a859 410 Gene3D G3DSA:3.90.180.10 27 221 4.3E-39 T 06-07-2017 IPR011032 GroES-like BWK49_RS22535 6b93a4524c773f5df038cbece3a219a1 380 Pfam PF00296 Luciferase-like monooxygenase 31 345 1.9E-48 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS22535 6b93a4524c773f5df038cbece3a219a1 380 Gene3D G3DSA:3.20.20.30 32 353 6.8E-62 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS22535 6b93a4524c773f5df038cbece3a219a1 380 SUPERFAMILY SSF51679 30 352 1.83E-53 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS21650 342db0687f637532a38b7381c035186c 306 Gene3D G3DSA:3.20.20.60 22 238 1.4E-59 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 BWK49_RS21650 342db0687f637532a38b7381c035186c 306 PIRSF PIRSF015582 6 293 1.6E-68 T 06-07-2017 IPR011206 Citrate lyase beta subunit-like BWK49_RS21650 342db0687f637532a38b7381c035186c 306 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 25 226 3.4E-25 T 06-07-2017 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 BWK49_RS21650 342db0687f637532a38b7381c035186c 306 SUPERFAMILY SSF51621 21 238 6.98E-54 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 BWK49_RS08760 d3298a0b48d2cca6a5542322075a22e1 383 Pfam PF00149 Calcineurin-like phosphoesterase 1 170 2.3E-14 T 06-07-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 BWK49_RS08760 d3298a0b48d2cca6a5542322075a22e1 383 PIRSF PIRSF033093 1 383 2.3E-168 T 06-07-2017 IPR014577 Uncharacterised conserved protein UCP033093, metallophosphoesterase-type BWK49_RS08760 d3298a0b48d2cca6a5542322075a22e1 383 SUPERFAMILY SSF56300 1 313 1.82E-39 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like BWK49_RS08760 d3298a0b48d2cca6a5542322075a22e1 383 Gene3D G3DSA:3.60.21.10 1 240 1.8E-39 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like BWK49_RS24910 58b2aa037353107b7e3a5978f6c6e9ad 545 Pfam PF13193 AMP-binding enzyme C-terminal domain 452 528 3.1E-14 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS24910 58b2aa037353107b7e3a5978f6c6e9ad 545 Gene3D G3DSA:2.30.38.10 362 433 1.1E-13 T 06-07-2017 BWK49_RS24910 58b2aa037353107b7e3a5978f6c6e9ad 545 Gene3D G3DSA:3.40.50.980 69 203 5.2E-23 T 06-07-2017 BWK49_RS24910 58b2aa037353107b7e3a5978f6c6e9ad 545 Gene3D G3DSA:3.30.300.30 439 534 2.1E-25 T 06-07-2017 BWK49_RS24910 58b2aa037353107b7e3a5978f6c6e9ad 545 Pfam PF00501 AMP-binding enzyme 69 443 6.1E-58 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS24910 58b2aa037353107b7e3a5978f6c6e9ad 545 Gene3D G3DSA:3.40.50.980 204 361 8.2E-26 T 06-07-2017 BWK49_RS24910 58b2aa037353107b7e3a5978f6c6e9ad 545 SUPERFAMILY SSF56801 65 536 9.42E-102 T 06-07-2017 BWK49_RS28165 c8432d7a1e4a89d18fa77f50804c7f3a 390 Gene3D G3DSA:3.40.50.300 189 339 4.1E-10 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS28165 c8432d7a1e4a89d18fa77f50804c7f3a 390 Gene3D G3DSA:3.40.50.300 86 135 4.1E-10 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS28165 c8432d7a1e4a89d18fa77f50804c7f3a 390 Pfam PF13469 Sulfotransferase family 87 335 2.1E-45 T 06-07-2017 BWK49_RS28165 c8432d7a1e4a89d18fa77f50804c7f3a 390 SUPERFAMILY SSF52540 205 355 9.11E-31 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS28165 c8432d7a1e4a89d18fa77f50804c7f3a 390 SUPERFAMILY SSF52540 83 132 9.11E-31 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS21340 5c633a014d0bbb436764fcd8c213d710 79 Gene3D G3DSA:3.40.30.10 1 74 3.3E-27 T 06-07-2017 IPR012336 Thioredoxin-like fold BWK49_RS21340 5c633a014d0bbb436764fcd8c213d710 79 TIGRFAM TIGR02194 GlrX_NrdH: glutaredoxin-like protein NrdH 3 73 8.2E-34 T 06-07-2017 IPR011909 Glutaredoxin-like protein NrdH GO:0045454 BWK49_RS21340 5c633a014d0bbb436764fcd8c213d710 79 Pfam PF00462 Glutaredoxin 3 61 5.2E-15 T 06-07-2017 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 BWK49_RS21340 5c633a014d0bbb436764fcd8c213d710 79 SUPERFAMILY SSF52833 1 72 6.12E-18 T 06-07-2017 IPR012336 Thioredoxin-like fold BWK49_RS27940 a6033616c746a6233c9b96a91e818403 254 Pfam PF09900 Predicted membrane protein (DUF2127) 81 222 5.3E-35 T 06-07-2017 IPR021125 Protein of unknown function DUF2127 BWK49_RS27940 a6033616c746a6233c9b96a91e818403 254 PIRSF PIRSF021485 1 254 7.5E-122 T 06-07-2017 IPR014511 Protein of unknown function DUF2068, transmembrane, subgroup BWK49_RS25900 de8ad52b723c5e03ee65f074e109c727 325 SUPERFAMILY SSF53850 80 309 2.18E-55 T 06-07-2017 BWK49_RS25900 de8ad52b723c5e03ee65f074e109c727 325 Gene3D G3DSA:3.40.190.10 88 171 7.3E-31 T 06-07-2017 BWK49_RS25900 de8ad52b723c5e03ee65f074e109c727 325 Gene3D G3DSA:3.40.190.10 273 309 7.3E-31 T 06-07-2017 BWK49_RS25900 de8ad52b723c5e03ee65f074e109c727 325 Gene3D G3DSA:3.40.190.10 172 272 3.1E-18 T 06-07-2017 BWK49_RS25900 de8ad52b723c5e03ee65f074e109c727 325 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 91 310 1.1E-52 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF BWK49_RS25900 de8ad52b723c5e03ee65f074e109c727 325 SMART SM00062 90 312 1.3E-71 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF BWK49_RS14340 c25af78eded9245c211f6166a66d7801 149 SUPERFAMILY SSF46785 9 143 4.18E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS14340 c25af78eded9245c211f6166a66d7801 149 Gene3D G3DSA:1.10.10.10 9 85 1.5E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS14340 c25af78eded9245c211f6166a66d7801 149 Pfam PF01475 Ferric uptake regulator family 18 107 5.3E-18 T 06-07-2017 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 BWK49_RS21205 aa3388c1fe92891e3371025650629bbb 348 Gene3D G3DSA:3.20.20.70 30 345 3.0E-105 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 BWK49_RS21205 aa3388c1fe92891e3371025650629bbb 348 Pfam PF01070 FMN-dependent dehydrogenase 9 101 8.1E-7 T 06-07-2017 IPR000262 FMN-dependent dehydrogenase GO:0016491 BWK49_RS21205 aa3388c1fe92891e3371025650629bbb 348 Pfam PF01070 FMN-dependent dehydrogenase 174 341 1.4E-17 T 06-07-2017 IPR000262 FMN-dependent dehydrogenase GO:0016491 BWK49_RS21205 aa3388c1fe92891e3371025650629bbb 348 SUPERFAMILY SSF51395 32 345 1.2E-69 T 06-07-2017 BWK49_RS21205 aa3388c1fe92891e3371025650629bbb 348 SMART SM01240 46 348 4.5E-4 T 06-07-2017 BWK49_RS21205 aa3388c1fe92891e3371025650629bbb 348 PIRSF PIRSF003314 5 348 1.2E-114 T 06-07-2017 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 BWK49_RS21205 aa3388c1fe92891e3371025650629bbb 348 Hamap MF_00354 Isopentenyl-diphosphate delta-isomerase [fni]. 8 348 35.514 T 06-07-2017 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 BWK49_RS21205 aa3388c1fe92891e3371025650629bbb 348 TIGRFAM TIGR02151 IPP_isom_2: isopentenyl-diphosphate delta-isomerase, type 2 10 345 2.5E-102 T 06-07-2017 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 BWK49_RS06675 66f24cc4e07939704ae442b25aaf362d 341 SUPERFAMILY SSF47240 76 244 6.17E-6 T 06-07-2017 IPR009078 Ferritin-like superfamily BWK49_RS06675 66f24cc4e07939704ae442b25aaf362d 341 Pfam PF11583 P-aminobenzoate N-oxygenase AurF 19 303 6.0E-110 T 06-07-2017 IPR025859 P-aminobenzoate N-oxygenase AurF BWK49_RS04775 b0deae5f43748f9935f58b512c5e2204 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 1.7E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS04775 b0deae5f43748f9935f58b512c5e2204 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 1.7E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS04775 b0deae5f43748f9935f58b512c5e2204 216 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 63 5.3E-12 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS04775 b0deae5f43748f9935f58b512c5e2204 216 SUPERFAMILY SSF46689 11 78 1.95E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS04775 b0deae5f43748f9935f58b512c5e2204 216 Gene3D G3DSA:1.10.357.10 12 206 1.4E-23 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS16320 a10c82cc6567113c105f9ef4f57dade0 113 Pfam PF00872 Transposase, Mutator family 24 92 1.5E-10 T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 BWK49_RS12785 3640e1d344b1b68c40f343c27615798e 593 Gene3D G3DSA:4.10.320.10 273 321 9.8E-20 T 06-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 BWK49_RS12785 3640e1d344b1b68c40f343c27615798e 593 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 06-07-2017 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 BWK49_RS12785 3640e1d344b1b68c40f343c27615798e 593 Pfam PF02817 e3 binding domain 278 312 1.4E-15 T 06-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 BWK49_RS12785 3640e1d344b1b68c40f343c27615798e 593 Pfam PF00364 Biotin-requiring enzyme 5 76 1.2E-21 T 06-07-2017 IPR000089 Biotin/lipoyl attachment BWK49_RS12785 3640e1d344b1b68c40f343c27615798e 593 Pfam PF00364 Biotin-requiring enzyme 132 203 8.9E-21 T 06-07-2017 IPR000089 Biotin/lipoyl attachment BWK49_RS12785 3640e1d344b1b68c40f343c27615798e 593 SUPERFAMILY SSF47005 271 316 7.59E-13 T 06-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 BWK49_RS12785 3640e1d344b1b68c40f343c27615798e 593 TIGRFAM TIGR02927 SucB_Actino: 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase 1 593 2.8E-287 T 06-07-2017 IPR014276 2-oxoglutarate dehydrogenase, E2 component KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00620+2.3.1.12 BWK49_RS12785 3640e1d344b1b68c40f343c27615798e 593 Gene3D G3DSA:3.30.559.10 343 584 1.0E-76 T 06-07-2017 IPR023213 Chloramphenicol acetyltransferase-like domain Reactome: R-HSA-389661 BWK49_RS12785 3640e1d344b1b68c40f343c27615798e 593 SUPERFAMILY SSF51230 130 222 4.97E-27 T 06-07-2017 IPR011053 Single hybrid motif BWK49_RS12785 3640e1d344b1b68c40f343c27615798e 593 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 357 584 9.0E-70 T 06-07-2017 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 BWK49_RS12785 3640e1d344b1b68c40f343c27615798e 593 Gene3D G3DSA:2.40.50.100 129 222 8.6E-30 T 06-07-2017 BWK49_RS12785 3640e1d344b1b68c40f343c27615798e 593 Gene3D G3DSA:2.40.50.100 1 95 9.0E-31 T 06-07-2017 BWK49_RS12785 3640e1d344b1b68c40f343c27615798e 593 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 154 183 - T 06-07-2017 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 BWK49_RS12785 3640e1d344b1b68c40f343c27615798e 593 SUPERFAMILY SSF51230 1 95 1.44E-27 T 06-07-2017 IPR011053 Single hybrid motif BWK49_RS12785 3640e1d344b1b68c40f343c27615798e 593 SUPERFAMILY SSF52777 343 584 3.83E-74 T 06-07-2017 BWK49_RS17745 f4afc4704abb74577de4a5eccb34aaaf 268 Pfam PF05711 Macrocin-O-methyltransferase (TylF) 10 267 7.1E-112 T 06-07-2017 IPR008884 Macrocin-O-methyltransferase BWK49_RS17745 f4afc4704abb74577de4a5eccb34aaaf 268 Gene3D G3DSA:3.40.50.150 162 232 5.7E-6 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS17745 f4afc4704abb74577de4a5eccb34aaaf 268 SUPERFAMILY SSF53335 173 234 2.49E-13 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS17745 f4afc4704abb74577de4a5eccb34aaaf 268 SUPERFAMILY SSF53335 80 135 2.49E-13 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS09615 7cb81b3930725d6f5a080ff05d49f14d 3084 Pfam PF08354 Domain of unknown function (DUF1729) 853 905 4.8E-21 T 06-07-2017 IPR013565 Domain of unknown function DUF1729 GO:0004318|GO:0055114 KEGG: 00061+4.2.1.59+2.3.1.39+1.3.1.9+3.1.2.14|KEGG: 00780+4.2.1.59|MetaCyc: PWY-4381|MetaCyc: PWY-5142|MetaCyc: PWY-5147|MetaCyc: PWY-5366|MetaCyc: PWY-5367|MetaCyc: PWY-5966|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-6799|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7723|MetaCyc: PWYG-321 BWK49_RS09615 7cb81b3930725d6f5a080ff05d49f14d 3084 Pfam PF01575 MaoC like domain 1209 1325 2.3E-28 T 06-07-2017 IPR002539 MaoC-like domain BWK49_RS09615 7cb81b3930725d6f5a080ff05d49f14d 3084 Gene3D G3DSA:3.40.366.10 1339 1479 3.5E-43 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 BWK49_RS09615 7cb81b3930725d6f5a080ff05d49f14d 3084 Gene3D G3DSA:3.40.366.10 37 187 3.5E-22 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 BWK49_RS09615 7cb81b3930725d6f5a080ff05d49f14d 3084 Gene3D G3DSA:3.40.366.10 1571 1625 3.5E-43 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 BWK49_RS09615 7cb81b3930725d6f5a080ff05d49f14d 3084 Gene3D G3DSA:3.40.366.10 289 380 3.5E-22 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 BWK49_RS09615 7cb81b3930725d6f5a080ff05d49f14d 3084 Gene3D G3DSA:3.40.366.10 1661 1731 3.5E-43 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 BWK49_RS09615 7cb81b3930725d6f5a080ff05d49f14d 3084 Gene3D G3DSA:3.40.47.10 2611 2834 1.3E-29 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS09615 7cb81b3930725d6f5a080ff05d49f14d 3084 Gene3D G3DSA:3.40.47.10 2456 2494 1.3E-29 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS09615 7cb81b3930725d6f5a080ff05d49f14d 3084 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2832 2956 1.8E-26 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal BWK49_RS09615 7cb81b3930725d6f5a080ff05d49f14d 3084 Gene3D G3DSA:3.40.50.720 2124 2375 1.0E-6 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS09615 7cb81b3930725d6f5a080ff05d49f14d 3084 SUPERFAMILY SSF51735 2132 2412 8.73E-10 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS09615 7cb81b3930725d6f5a080ff05d49f14d 3084 SUPERFAMILY SSF52151 1342 1485 1.27E-30 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 BWK49_RS09615 7cb81b3930725d6f5a080ff05d49f14d 3084 SUPERFAMILY SSF52151 1573 1594 1.27E-30 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 BWK49_RS09615 7cb81b3930725d6f5a080ff05d49f14d 3084 SUPERFAMILY SSF52151 1634 1714 1.27E-30 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 BWK49_RS09615 7cb81b3930725d6f5a080ff05d49f14d 3084 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 44 380 1.8E-4 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain BWK49_RS09615 7cb81b3930725d6f5a080ff05d49f14d 3084 PRINTS PR01483 Fatty acid synthase signature 416 436 2.9E-109 T 06-07-2017 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 BWK49_RS09615 7cb81b3930725d6f5a080ff05d49f14d 3084 PRINTS PR01483 Fatty acid synthase signature 567 586 2.9E-109 T 06-07-2017 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 BWK49_RS09615 7cb81b3930725d6f5a080ff05d49f14d 3084 PRINTS PR01483 Fatty acid synthase signature 1355 1378 2.9E-109 T 06-07-2017 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 BWK49_RS09615 7cb81b3930725d6f5a080ff05d49f14d 3084 PRINTS PR01483 Fatty acid synthase signature 1334 1353 2.9E-109 T 06-07-2017 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 BWK49_RS09615 7cb81b3930725d6f5a080ff05d49f14d 3084 PRINTS PR01483 Fatty acid synthase signature 1436 1455 2.9E-109 T 06-07-2017 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 BWK49_RS09615 7cb81b3930725d6f5a080ff05d49f14d 3084 PRINTS PR01483 Fatty acid synthase signature 847 871 2.9E-109 T 06-07-2017 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 BWK49_RS09615 7cb81b3930725d6f5a080ff05d49f14d 3084 PRINTS PR01483 Fatty acid synthase signature 1472 1493 2.9E-109 T 06-07-2017 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 BWK49_RS09615 7cb81b3930725d6f5a080ff05d49f14d 3084 PRINTS PR01483 Fatty acid synthase signature 442 460 2.9E-109 T 06-07-2017 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 BWK49_RS09615 7cb81b3930725d6f5a080ff05d49f14d 3084 PRINTS PR01483 Fatty acid synthase signature 547 565 2.9E-109 T 06-07-2017 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 BWK49_RS09615 7cb81b3930725d6f5a080ff05d49f14d 3084 PRINTS PR01483 Fatty acid synthase signature 1227 1249 2.9E-109 T 06-07-2017 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 BWK49_RS09615 7cb81b3930725d6f5a080ff05d49f14d 3084 PRINTS PR01483 Fatty acid synthase signature 737 755 2.9E-109 T 06-07-2017 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 BWK49_RS09615 7cb81b3930725d6f5a080ff05d49f14d 3084 PRINTS PR01483 Fatty acid synthase signature 1249 1270 2.9E-109 T 06-07-2017 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 BWK49_RS09615 7cb81b3930725d6f5a080ff05d49f14d 3084 Pfam PF00698 Acyl transferase domain 1343 1548 5.1E-37 T 06-07-2017 IPR014043 Acyl transferase BWK49_RS09615 7cb81b3930725d6f5a080ff05d49f14d 3084 SUPERFAMILY SSF53901 2601 2830 1.97E-27 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS09615 7cb81b3930725d6f5a080ff05d49f14d 3084 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2590 2819 8.9E-34 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal BWK49_RS09615 7cb81b3930725d6f5a080ff05d49f14d 3084 SMART SM00825 Beta-ketoacyl synthase 2589 2996 8.2E-4 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain BWK49_RS09615 7cb81b3930725d6f5a080ff05d49f14d 3084 SUPERFAMILY SSF54637 1220 1336 2.27E-22 T 06-07-2017 IPR029069 HotDog domain BWK49_RS09615 7cb81b3930725d6f5a080ff05d49f14d 3084 SUPERFAMILY SSF53901 2791 3006 8.86E-34 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS09615 7cb81b3930725d6f5a080ff05d49f14d 3084 Gene3D G3DSA:3.10.129.10 1175 1338 2.7E-35 T 06-07-2017 IPR029069 HotDog domain BWK49_RS09615 7cb81b3930725d6f5a080ff05d49f14d 3084 SUPERFAMILY SSF51412 404 672 2.01E-16 T 06-07-2017 BWK49_RS09615 7cb81b3930725d6f5a080ff05d49f14d 3084 Gene3D G3DSA:3.40.47.10 2841 2995 1.8E-29 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS09615 7cb81b3930725d6f5a080ff05d49f14d 3084 SUPERFAMILY SSF52151 41 193 1.7E-18 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 BWK49_RS09615 7cb81b3930725d6f5a080ff05d49f14d 3084 SUPERFAMILY SSF52151 291 374 1.7E-18 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 BWK49_RS09615 7cb81b3930725d6f5a080ff05d49f14d 3084 Gene3D G3DSA:3.20.20.70 402 703 2.9E-25 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 BWK49_RS24025 38159869be1e2bdac4ca5853b6278e9e 73 SUPERFAMILY SSF50249 4 72 1.47E-26 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS24025 38159869be1e2bdac4ca5853b6278e9e 73 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 4 72 6.9E-38 T 06-07-2017 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 BWK49_RS24025 38159869be1e2bdac4ca5853b6278e9e 73 Gene3D G3DSA:2.40.50.140 2 73 6.0E-39 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS24025 38159869be1e2bdac4ca5853b6278e9e 73 Pfam PF01176 Translation initiation factor 1A / IF-1 8 71 1.2E-28 T 06-07-2017 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 BWK49_RS24025 38159869be1e2bdac4ca5853b6278e9e 73 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 2 73 26.479 T 06-07-2017 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 BWK49_RS11950 0abceaf67e7920a5ee90e66627aaca15 143 SUPERFAMILY SSF50475 46 139 2.55E-5 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 BWK49_RS11950 0abceaf67e7920a5ee90e66627aaca15 143 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 28 140 1.4E-30 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 BWK49_RS11950 0abceaf67e7920a5ee90e66627aaca15 143 Pfam PF04075 Domain of unknown function (DUF385) 17 138 1.2E-33 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 BWK49_RS20215 7a1c01ed469305d9bb3142e086c1eee6 298 Gene3D G3DSA:1.10.443.10 112 290 8.0E-51 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 BWK49_RS20215 7a1c01ed469305d9bb3142e086c1eee6 298 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 3 298 53.992 T 06-07-2017 IPR023009 Tyrosine recombinase XerC/XerD BWK49_RS20215 7a1c01ed469305d9bb3142e086c1eee6 298 Gene3D G3DSA:1.10.150.130 3 97 6.3E-21 T 06-07-2017 IPR023109 Integrase/recombinase, N-terminal BWK49_RS20215 7a1c01ed469305d9bb3142e086c1eee6 298 SUPERFAMILY SSF56349 8 291 4.71E-49 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 BWK49_RS20215 7a1c01ed469305d9bb3142e086c1eee6 298 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 5 87 9.7E-19 T 06-07-2017 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 BWK49_RS20215 7a1c01ed469305d9bb3142e086c1eee6 298 Pfam PF00589 Phage integrase family 109 283 3.6E-46 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 BWK49_RS11990 cd6f2444b38932f59400c9fdde094f81 206 SUPERFAMILY SSF109854 6 112 5.49E-8 T 06-07-2017 BWK49_RS11990 cd6f2444b38932f59400c9fdde094f81 206 TIGRFAM TIGR03085 TIGR03085: TIGR03085 family protein 4 199 7.8E-77 T 06-07-2017 IPR017519 Conserved hypothetical protein CHP03085 BWK49_RS11990 cd6f2444b38932f59400c9fdde094f81 206 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 8 67 2.8E-5 T 06-07-2017 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 BWK49_RS11990 cd6f2444b38932f59400c9fdde094f81 206 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 4 183 1.5E-35 T 06-07-2017 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type BWK49_RS03365 59f0c428ec1b82bcd3c91b2a0ea246e4 291 SUPERFAMILY SSF100950 3 281 5.98E-67 T 06-07-2017 BWK49_RS03365 59f0c428ec1b82bcd3c91b2a0ea246e4 291 SMART SM00882 5 232 1.5E-26 T 06-07-2017 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 BWK49_RS03365 59f0c428ec1b82bcd3c91b2a0ea246e4 291 Pfam PF01144 Coenzyme A transferase 6 232 3.5E-47 T 06-07-2017 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 BWK49_RS03365 59f0c428ec1b82bcd3c91b2a0ea246e4 291 Gene3D G3DSA:3.40.1080.10 3 118 1.7E-74 T 06-07-2017 BWK49_RS03365 59f0c428ec1b82bcd3c91b2a0ea246e4 291 Gene3D G3DSA:3.40.1080.10 161 284 1.7E-74 T 06-07-2017 BWK49_RS05340 6f5e538f9c9aba87c41529f440a2a8b8 247 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 66 1.7E-13 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS05340 6f5e538f9c9aba87c41529f440a2a8b8 247 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 6.5E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS05340 6f5e538f9c9aba87c41529f440a2a8b8 247 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 6.5E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS05340 6f5e538f9c9aba87c41529f440a2a8b8 247 Gene3D G3DSA:1.10.357.10 16 188 2.1E-22 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS05340 6f5e538f9c9aba87c41529f440a2a8b8 247 SUPERFAMILY SSF46689 11 85 4.98E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS03410 f3566376a1d97b6a8578e33c6167074e 337 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 19 99 8.5E-11 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS03410 f3566376a1d97b6a8578e33c6167074e 337 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 204 326 2.8E-16 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS03410 f3566376a1d97b6a8578e33c6167074e 337 SUPERFAMILY SSF56645 1 190 2.88E-26 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS03410 f3566376a1d97b6a8578e33c6167074e 337 Gene3D G3DSA:1.10.540.10 26 99 4.1E-11 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS03410 f3566376a1d97b6a8578e33c6167074e 337 Gene3D G3DSA:2.40.110.10 125 191 1.5E-4 T 06-07-2017 BWK49_RS03410 f3566376a1d97b6a8578e33c6167074e 337 Gene3D G3DSA:1.20.140.10 204 323 1.5E-22 T 06-07-2017 BWK49_RS03410 f3566376a1d97b6a8578e33c6167074e 337 SUPERFAMILY SSF47203 202 333 2.58E-24 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS24205 d5831f2b19da84e7ad917e5f9afeabe3 595 Pfam PF01343 Peptidase family S49 112 264 4.6E-42 T 06-07-2017 IPR002142 Peptidase S49 GO:0006508|GO:0008233 BWK49_RS24205 d5831f2b19da84e7ad917e5f9afeabe3 595 Pfam PF01343 Peptidase family S49 375 526 1.6E-50 T 06-07-2017 IPR002142 Peptidase S49 GO:0006508|GO:0008233 BWK49_RS24205 d5831f2b19da84e7ad917e5f9afeabe3 595 TIGRFAM TIGR00706 SppA_dom: signal peptide peptidase SppA, 36K type 304 524 2.0E-52 T 06-07-2017 IPR004635 Peptidase S49, SppA GO:0006508|GO:0008233 BWK49_RS24205 d5831f2b19da84e7ad917e5f9afeabe3 595 Gene3D G3DSA:3.90.226.10 299 415 4.7E-62 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS24205 d5831f2b19da84e7ad917e5f9afeabe3 595 Gene3D G3DSA:3.90.226.10 453 530 4.7E-62 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS24205 d5831f2b19da84e7ad917e5f9afeabe3 595 Gene3D G3DSA:3.90.226.10 64 141 1.6E-24 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS24205 d5831f2b19da84e7ad917e5f9afeabe3 595 Gene3D G3DSA:3.90.226.10 224 267 1.6E-24 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS24205 d5831f2b19da84e7ad917e5f9afeabe3 595 SUPERFAMILY SSF52096 191 252 3.2E-21 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS24205 d5831f2b19da84e7ad917e5f9afeabe3 595 SUPERFAMILY SSF52096 59 158 3.2E-21 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS24205 d5831f2b19da84e7ad917e5f9afeabe3 595 PIRSF PIRSF001217 7 577 9.8E-162 T 06-07-2017 IPR004634 Peptidase S49, protease IV GO:0006465|GO:0008233|GO:0016021 BWK49_RS24205 d5831f2b19da84e7ad917e5f9afeabe3 595 Gene3D G3DSA:3.40.1750.10 142 219 5.2E-17 T 06-07-2017 BWK49_RS24205 d5831f2b19da84e7ad917e5f9afeabe3 595 SUPERFAMILY SSF52096 452 512 4.07E-43 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS24205 d5831f2b19da84e7ad917e5f9afeabe3 595 SUPERFAMILY SSF52096 295 423 4.07E-43 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS07040 b65364d520a930d8d161b0de1ec8bf64 267 SUPERFAMILY SSF52096 13 266 5.13E-65 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS07040 b65364d520a930d8d161b0de1ec8bf64 267 Pfam PF00378 Enoyl-CoA hydratase/isomerase 18 266 2.1E-42 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 BWK49_RS07040 b65364d520a930d8d161b0de1ec8bf64 267 Gene3D G3DSA:3.90.226.10 13 203 1.2E-46 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS07040 b65364d520a930d8d161b0de1ec8bf64 267 Gene3D G3DSA:1.10.12.10 211 266 2.6E-16 T 06-07-2017 IPR014748 Crontonase, C-terminal BWK49_RS18815 187ab6ee0ecbeda4f00a34abced77735 1170 Pfam PF00550 Phosphopantetheine attachment site 654 719 1.4E-9 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS18815 187ab6ee0ecbeda4f00a34abced77735 1170 Gene3D G3DSA:1.10.1200.10 649 724 1.2E-10 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS18815 187ab6ee0ecbeda4f00a34abced77735 1170 TIGRFAM TIGR01746 Thioester-redct: thioester reductase domain 773 1169 1.6E-94 T 06-07-2017 IPR010080 Thioester reductase-like domain BWK49_RS18815 187ab6ee0ecbeda4f00a34abced77735 1170 Gene3D G3DSA:2.30.38.10 433 503 1.1E-12 T 06-07-2017 BWK49_RS18815 187ab6ee0ecbeda4f00a34abced77735 1170 Gene3D G3DSA:3.40.50.980 45 251 1.4E-22 T 06-07-2017 BWK49_RS18815 187ab6ee0ecbeda4f00a34abced77735 1170 Gene3D G3DSA:3.40.50.720 773 1090 3.0E-27 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS18815 187ab6ee0ecbeda4f00a34abced77735 1170 SUPERFAMILY SSF47336 648 732 6.02E-12 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS18815 187ab6ee0ecbeda4f00a34abced77735 1170 Pfam PF07993 Male sterility protein 776 1038 2.0E-57 T 06-07-2017 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 BWK49_RS18815 187ab6ee0ecbeda4f00a34abced77735 1170 SUPERFAMILY SSF56801 43 634 2.49E-90 T 06-07-2017 BWK49_RS18815 187ab6ee0ecbeda4f00a34abced77735 1170 Pfam PF00501 AMP-binding enzyme 83 510 2.1E-65 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS18815 187ab6ee0ecbeda4f00a34abced77735 1170 SMART SM00823 Phosphopantetheine attachment site 651 723 8.3E-5 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS18815 187ab6ee0ecbeda4f00a34abced77735 1170 SUPERFAMILY SSF51735 772 1093 4.11E-31 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS18815 187ab6ee0ecbeda4f00a34abced77735 1170 ProSitePatterns PS00455 Putative AMP-binding domain signature. 246 257 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS18815 187ab6ee0ecbeda4f00a34abced77735 1170 Gene3D G3DSA:3.40.50.980 252 421 1.5E-24 T 06-07-2017 BWK49_RS28050 74dcc7913e7dbdd267fb3b611df74d5d 70 Pfam PF00403 Heavy-metal-associated domain 6 64 6.9E-14 T 06-07-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 BWK49_RS28050 74dcc7913e7dbdd267fb3b611df74d5d 70 SUPERFAMILY SSF55008 2 68 1.02E-16 T 06-07-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 BWK49_RS28050 74dcc7913e7dbdd267fb3b611df74d5d 70 Gene3D G3DSA:3.30.70.100 5 69 2.8E-19 T 06-07-2017 BWK49_RS21140 da261101d2fdb842207e856433434bab 317 SUPERFAMILY SSF48576 19 303 2.16E-68 T 06-07-2017 IPR008949 Isoprenoid synthase domain BWK49_RS21140 da261101d2fdb842207e856433434bab 317 Pfam PF00494 Squalene/phytoene synthase 29 288 9.4E-59 T 06-07-2017 IPR002060 Squalene/phytoene synthase GO:0009058|GO:0016740 BWK49_RS21140 da261101d2fdb842207e856433434bab 317 Gene3D G3DSA:1.10.600.10 15 301 9.8E-72 T 06-07-2017 IPR008949 Isoprenoid synthase domain BWK49_RS21140 da261101d2fdb842207e856433434bab 317 ProSitePatterns PS01045 Squalene and phytoene synthases signature 2. 172 197 - T 06-07-2017 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 BWK49_RS14870 130771065e8cd901d72abfef2b6d5c71 110 Pfam PF04993 TfoX N-terminal domain 13 104 1.7E-16 T 06-07-2017 IPR007076 TfoX, N-terminal BWK49_RS14870 130771065e8cd901d72abfef2b6d5c71 110 SUPERFAMILY SSF159894 6 105 3.4E-13 T 06-07-2017 BWK49_RS14870 130771065e8cd901d72abfef2b6d5c71 110 Gene3D G3DSA:3.30.1460.30 8 105 1.5E-5 T 06-07-2017 IPR007076 TfoX, N-terminal BWK49_RS24010 1754b65f3876fda8946f3196c873d4ca 138 PIRSF PIRSF002131 6 138 2.8E-54 T 06-07-2017 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 BWK49_RS24010 1754b65f3876fda8946f3196c873d4ca 138 SUPERFAMILY SSF53137 23 138 1.25E-49 T 06-07-2017 BWK49_RS24010 1754b65f3876fda8946f3196c873d4ca 138 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 5 138 33.698 T 06-07-2017 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 BWK49_RS24010 1754b65f3876fda8946f3196c873d4ca 138 Gene3D G3DSA:3.30.420.80 15 138 1.7E-56 T 06-07-2017 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 BWK49_RS24010 1754b65f3876fda8946f3196c873d4ca 138 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 19 135 4.7E-58 T 06-07-2017 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS24010 1754b65f3876fda8946f3196c873d4ca 138 ProSitePatterns PS00054 Ribosomal protein S11 signature. 106 128 - T 06-07-2017 IPR018102 Ribosomal S11, conserved site BWK49_RS24010 1754b65f3876fda8946f3196c873d4ca 138 Pfam PF00411 Ribosomal protein S11 28 137 6.9E-49 T 06-07-2017 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 BWK49_RS27475 b859014e1fe38e43cf677cccbc09bec2 313 SUPERFAMILY SSF53335 17 293 1.08E-85 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS27475 b859014e1fe38e43cf677cccbc09bec2 313 Gene3D G3DSA:3.40.50.150 18 239 9.5E-22 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS27475 b859014e1fe38e43cf677cccbc09bec2 313 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 19 287 1.2E-91 T 06-07-2017 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 BWK49_RS27475 b859014e1fe38e43cf677cccbc09bec2 313 Pfam PF04072 Leucine carboxyl methyltransferase 21 207 3.6E-67 T 06-07-2017 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 BWK49_RS21395 14a98e31f49993d3a8a0e5e18fcbe791 485 SUPERFAMILY SSF46785 254 327 5.44E-7 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS21395 14a98e31f49993d3a8a0e5e18fcbe791 485 Gene3D G3DSA:1.20.120.530 348 481 4.6E-12 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal BWK49_RS21395 14a98e31f49993d3a8a0e5e18fcbe791 485 Pfam PF07729 FCD domain 103 226 2.4E-18 T 06-07-2017 IPR011711 GntR, C-terminal BWK49_RS21395 14a98e31f49993d3a8a0e5e18fcbe791 485 Pfam PF07729 FCD domain 349 478 4.6E-12 T 06-07-2017 IPR011711 GntR, C-terminal BWK49_RS21395 14a98e31f49993d3a8a0e5e18fcbe791 485 SMART SM00345 17 78 8.1E-6 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 BWK49_RS21395 14a98e31f49993d3a8a0e5e18fcbe791 485 Pfam PF00392 Bacterial regulatory proteins, gntR family 17 71 2.8E-7 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 BWK49_RS21395 14a98e31f49993d3a8a0e5e18fcbe791 485 SMART SM00895 349 479 1.7E-7 T 06-07-2017 IPR011711 GntR, C-terminal BWK49_RS21395 14a98e31f49993d3a8a0e5e18fcbe791 485 SMART SM00895 103 227 6.2E-17 T 06-07-2017 IPR011711 GntR, C-terminal BWK49_RS21395 14a98e31f49993d3a8a0e5e18fcbe791 485 SUPERFAMILY SSF48008 348 484 9.94E-13 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal BWK49_RS21395 14a98e31f49993d3a8a0e5e18fcbe791 485 Gene3D G3DSA:1.20.120.530 101 232 4.7E-19 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal BWK49_RS21395 14a98e31f49993d3a8a0e5e18fcbe791 485 Gene3D G3DSA:1.10.10.10 256 328 1.5E-8 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS21395 14a98e31f49993d3a8a0e5e18fcbe791 485 Gene3D G3DSA:1.10.10.10 12 81 1.2E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS21395 14a98e31f49993d3a8a0e5e18fcbe791 485 SUPERFAMILY SSF48008 102 234 7.85E-20 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal BWK49_RS21395 14a98e31f49993d3a8a0e5e18fcbe791 485 SUPERFAMILY SSF46785 12 82 8.17E-10 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS11925 194fd1d09ae339dd5e1448b61201f73e 533 Pfam PF13671 AAA domain 352 502 2.4E-29 T 06-07-2017 BWK49_RS11925 194fd1d09ae339dd5e1448b61201f73e 533 SUPERFAMILY SSF56112 13 306 1.6E-21 T 06-07-2017 IPR011009 Protein kinase-like domain BWK49_RS11925 194fd1d09ae339dd5e1448b61201f73e 533 Gene3D G3DSA:3.90.1200.10 137 303 1.2E-6 T 06-07-2017 BWK49_RS11925 194fd1d09ae339dd5e1448b61201f73e 533 SUPERFAMILY SSF52540 348 530 8.79E-26 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS11925 194fd1d09ae339dd5e1448b61201f73e 533 Gene3D G3DSA:3.40.50.300 348 529 1.3E-26 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS11175 769301b51881a939dc2e06ae4b1229ff 255 Pfam PF10006 Uncharacterized conserved protein (DUF2249) 185 252 1.4E-23 T 06-07-2017 IPR018720 Domain of unknown function DUF2249 BWK49_RS11175 769301b51881a939dc2e06ae4b1229ff 255 Gene3D G3DSA:1.20.120.520 17 142 8.8E-9 T 06-07-2017 BWK49_RS11175 769301b51881a939dc2e06ae4b1229ff 255 Pfam PF01814 Hemerythrin HHE cation binding domain 18 140 1.5E-13 T 06-07-2017 IPR012312 Haemerythrin-like Reactome: R-HSA-390471 BWK49_RS07385 9b187f9cc3a81619be858988e5ae162e 196 Gene3D G3DSA:1.10.10.60 5 64 4.7E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS07385 9b187f9cc3a81619be858988e5ae162e 196 SUPERFAMILY SSF48498 85 177 6.97E-17 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS07385 9b187f9cc3a81619be858988e5ae162e 196 SUPERFAMILY SSF46689 6 79 4.82E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS07385 9b187f9cc3a81619be858988e5ae162e 196 Pfam PF13305 WHG domain 92 172 4.2E-14 T 06-07-2017 IPR025996 WHG domain BWK49_RS07385 9b187f9cc3a81619be858988e5ae162e 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 61 2.0E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS07385 9b187f9cc3a81619be858988e5ae162e 196 Gene3D G3DSA:1.10.357.10 65 183 8.3E-23 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS24030 35d043a5be432039c730d1455bcf135c 554 Gene3D G3DSA:3.50.50.60 338 546 1.6E-26 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS24030 35d043a5be432039c730d1455bcf135c 554 Gene3D G3DSA:3.40.50.2300 12 142 6.7E-22 T 06-07-2017 BWK49_RS24030 35d043a5be432039c730d1455bcf135c 554 SMART SM00448 10 132 1.9E-12 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 BWK49_RS24030 35d043a5be432039c730d1455bcf135c 554 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 235 254 1.3E-24 T 06-07-2017 BWK49_RS24030 35d043a5be432039c730d1455bcf135c 554 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 334 352 1.3E-24 T 06-07-2017 BWK49_RS24030 35d043a5be432039c730d1455bcf135c 554 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 504 526 1.3E-24 T 06-07-2017 BWK49_RS24030 35d043a5be432039c730d1455bcf135c 554 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 463 479 1.3E-24 T 06-07-2017 BWK49_RS24030 35d043a5be432039c730d1455bcf135c 554 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 377 395 1.3E-24 T 06-07-2017 BWK49_RS24030 35d043a5be432039c730d1455bcf135c 554 SUPERFAMILY SSF51905 233 553 1.73E-37 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS24030 35d043a5be432039c730d1455bcf135c 554 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 233 540 7.0E-31 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS24030 35d043a5be432039c730d1455bcf135c 554 Gene3D G3DSA:3.50.50.60 231 337 1.8E-31 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS24030 35d043a5be432039c730d1455bcf135c 554 Pfam PF00072 Response regulator receiver domain 13 124 6.2E-13 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 BWK49_RS24030 35d043a5be432039c730d1455bcf135c 554 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 234 256 5.1E-37 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 BWK49_RS24030 35d043a5be432039c730d1455bcf135c 554 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 373 397 5.1E-37 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 BWK49_RS24030 35d043a5be432039c730d1455bcf135c 554 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 514 532 5.1E-37 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 BWK49_RS24030 35d043a5be432039c730d1455bcf135c 554 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 288 298 5.1E-37 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 BWK49_RS24030 35d043a5be432039c730d1455bcf135c 554 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 267 282 5.1E-37 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 BWK49_RS24030 35d043a5be432039c730d1455bcf135c 554 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 335 343 5.1E-37 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 BWK49_RS24030 35d043a5be432039c730d1455bcf135c 554 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 427 443 5.1E-37 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 BWK49_RS24030 35d043a5be432039c730d1455bcf135c 554 SUPERFAMILY SSF52172 12 144 2.28E-20 T 06-07-2017 IPR011006 CheY-like superfamily BWK49_RS17435 f1857a8372c8b1f0dac9f366e0bb2cd2 434 TIGRFAM TIGR00508 bioA: adenosylmethionine-8-amino-7-oxononanoate transaminase 21 430 3.7E-164 T 06-07-2017 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 BWK49_RS17435 f1857a8372c8b1f0dac9f366e0bb2cd2 434 SUPERFAMILY SSF53383 12 429 1.3E-118 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase BWK49_RS17435 f1857a8372c8b1f0dac9f366e0bb2cd2 434 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 251 288 - T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 BWK49_RS17435 f1857a8372c8b1f0dac9f366e0bb2cd2 434 Gene3D G3DSA:3.90.1150.10 11 73 2.8E-48 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 BWK49_RS17435 f1857a8372c8b1f0dac9f366e0bb2cd2 434 Gene3D G3DSA:3.90.1150.10 341 430 2.8E-48 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 BWK49_RS17435 f1857a8372c8b1f0dac9f366e0bb2cd2 434 Pfam PF00202 Aminotransferase class-III 36 429 2.4E-115 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 BWK49_RS17435 f1857a8372c8b1f0dac9f366e0bb2cd2 434 Hamap MF_00834 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [bioA]. 9 433 49.205 T 06-07-2017 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 BWK49_RS17435 f1857a8372c8b1f0dac9f366e0bb2cd2 434 Gene3D G3DSA:3.40.640.10 74 336 2.1E-85 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 BWK49_RS21440 3b1c6b3ff9849c9c96346d440200ea8c 406 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 5 404 1.4E-114 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 BWK49_RS21440 3b1c6b3ff9849c9c96346d440200ea8c 406 PIRSF PIRSF000429 1 406 4.3E-101 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 BWK49_RS21440 3b1c6b3ff9849c9c96346d440200ea8c 406 Gene3D G3DSA:3.40.47.10 140 184 2.4E-54 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS21440 3b1c6b3ff9849c9c96346d440200ea8c 406 Gene3D G3DSA:3.40.47.10 290 405 2.4E-54 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS21440 3b1c6b3ff9849c9c96346d440200ea8c 406 Gene3D G3DSA:3.40.47.10 185 289 1.2E-55 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS21440 3b1c6b3ff9849c9c96346d440200ea8c 406 Gene3D G3DSA:3.40.47.10 2 125 1.2E-55 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS21440 3b1c6b3ff9849c9c96346d440200ea8c 406 SUPERFAMILY SSF53901 2 226 6.01E-56 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS21440 3b1c6b3ff9849c9c96346d440200ea8c 406 SUPERFAMILY SSF53901 254 281 6.01E-56 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS21440 3b1c6b3ff9849c9c96346d440200ea8c 406 Pfam PF02803 Thiolase, C-terminal domain 284 405 5.5E-44 T 06-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 BWK49_RS21440 3b1c6b3ff9849c9c96346d440200ea8c 406 ProSitePatterns PS00737 Thiolases signature 2. 352 368 - T 06-07-2017 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 BWK49_RS21440 3b1c6b3ff9849c9c96346d440200ea8c 406 Pfam PF00108 Thiolase, N-terminal domain 5 230 8.7E-39 T 06-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 BWK49_RS21440 3b1c6b3ff9849c9c96346d440200ea8c 406 ProSitePatterns PS00099 Thiolases active site. 387 400 - T 06-07-2017 IPR020610 Thiolase, active site GO:0008152|GO:0016747 BWK49_RS21440 3b1c6b3ff9849c9c96346d440200ea8c 406 SUPERFAMILY SSF53901 284 405 2.88E-42 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS16110 3b405ab9dbb831eed917b8e5648c2a78 760 Pfam PF00122 E1-E2 ATPase 185 396 2.1E-53 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 BWK49_RS16110 3b405ab9dbb831eed917b8e5648c2a78 760 ProSitePatterns PS01229 Hypothetical cof family signature 2. 607 629 - T 06-07-2017 BWK49_RS16110 3b405ab9dbb831eed917b8e5648c2a78 760 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 185 688 8.6E-75 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 BWK49_RS16110 3b405ab9dbb831eed917b8e5648c2a78 760 Gene3D G3DSA:3.40.1110.10 424 532 1.3E-20 T 06-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 BWK49_RS16110 3b405ab9dbb831eed917b8e5648c2a78 760 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 144 710 1.3E-126 T 06-07-2017 BWK49_RS16110 3b405ab9dbb831eed917b8e5648c2a78 760 Gene3D G3DSA:3.40.50.1000 533 653 1.2E-42 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS16110 3b405ab9dbb831eed917b8e5648c2a78 760 SUPERFAMILY SSF81653 220 312 6.54E-22 T 06-07-2017 BWK49_RS16110 3b405ab9dbb831eed917b8e5648c2a78 760 SUPERFAMILY SSF81665 314 425 2.62E-5 T 06-07-2017 BWK49_RS16110 3b405ab9dbb831eed917b8e5648c2a78 760 SUPERFAMILY SSF81665 168 216 2.62E-5 T 06-07-2017 BWK49_RS16110 3b405ab9dbb831eed917b8e5648c2a78 760 SUPERFAMILY SSF56784 463 707 2.8E-55 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS16110 3b405ab9dbb831eed917b8e5648c2a78 760 SUPERFAMILY SSF56784 404 423 2.8E-55 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS16110 3b405ab9dbb831eed917b8e5648c2a78 760 Pfam PF00702 haloacid dehalogenase-like hydrolase 401 621 4.4E-44 T 06-07-2017 BWK49_RS16110 3b405ab9dbb831eed917b8e5648c2a78 760 Gene3D G3DSA:3.40.1110.10 396 423 3.3E-4 T 06-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 BWK49_RS16110 3b405ab9dbb831eed917b8e5648c2a78 760 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 554 564 2.3E-26 T 06-07-2017 BWK49_RS16110 3b405ab9dbb831eed917b8e5648c2a78 760 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 531 542 2.3E-26 T 06-07-2017 BWK49_RS16110 3b405ab9dbb831eed917b8e5648c2a78 760 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 607 626 2.3E-26 T 06-07-2017 BWK49_RS16110 3b405ab9dbb831eed917b8e5648c2a78 760 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 405 419 2.3E-26 T 06-07-2017 BWK49_RS16110 3b405ab9dbb831eed917b8e5648c2a78 760 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 631 643 2.3E-26 T 06-07-2017 BWK49_RS16110 3b405ab9dbb831eed917b8e5648c2a78 760 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 263 277 2.3E-26 T 06-07-2017 BWK49_RS16110 3b405ab9dbb831eed917b8e5648c2a78 760 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 163 710 3.6E-173 T 06-07-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 BWK49_RS16110 3b405ab9dbb831eed917b8e5648c2a78 760 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 407 413 - T 06-07-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 BWK49_RS16110 3b405ab9dbb831eed917b8e5648c2a78 760 Gene3D G3DSA:2.70.150.10 214 313 5.5E-21 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 BWK49_RS24310 5162625733c64cf87644df5bef5d01b4 280 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 273 4.3E-128 T 06-07-2017 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS24310 5162625733c64cf87644df5bef5d01b4 280 Gene3D G3DSA:4.10.950.10 197 273 4.4E-31 T 06-07-2017 IPR014726 Ribosomal protein L2, domain 3 BWK49_RS24310 5162625733c64cf87644df5bef5d01b4 280 Gene3D G3DSA:2.30.30.30 120 196 2.1E-30 T 06-07-2017 IPR014722 Ribosomal protein L2 domain 2 BWK49_RS24310 5162625733c64cf87644df5bef5d01b4 280 ProSitePatterns PS00467 Ribosomal protein L2 signature. 219 230 - T 06-07-2017 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 BWK49_RS24310 5162625733c64cf87644df5bef5d01b4 280 Gene3D G3DSA:2.40.50.140 1 115 1.7E-50 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS24310 5162625733c64cf87644df5bef5d01b4 280 SMART SM01383 42 119 1.7E-41 T 06-07-2017 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS24310 5162625733c64cf87644df5bef5d01b4 280 SUPERFAMILY SSF50104 127 271 3.07E-55 T 06-07-2017 IPR008991 Translation protein SH3-like domain BWK49_RS24310 5162625733c64cf87644df5bef5d01b4 280 SUPERFAMILY SSF50249 2 126 1.71E-49 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS24310 5162625733c64cf87644df5bef5d01b4 280 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 273 48.023 T 06-07-2017 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS24310 5162625733c64cf87644df5bef5d01b4 280 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 126 251 8.2E-55 T 06-07-2017 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 BWK49_RS24310 5162625733c64cf87644df5bef5d01b4 280 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 118 1.7E-33 T 06-07-2017 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS24310 5162625733c64cf87644df5bef5d01b4 280 SMART SM01382 125 253 3.7E-88 T 06-07-2017 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 BWK49_RS24310 5162625733c64cf87644df5bef5d01b4 280 PIRSF PIRSF002158 4 275 1.4E-93 T 06-07-2017 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS04635 a4da991884af10ca65de3463bc2cb0dc 213 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 72 1.6E-12 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS04635 a4da991884af10ca65de3463bc2cb0dc 213 Gene3D G3DSA:1.10.357.10 71 205 4.5E-15 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS04635 a4da991884af10ca65de3463bc2cb0dc 213 SUPERFAMILY SSF48498 88 206 1.61E-12 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS04635 a4da991884af10ca65de3463bc2cb0dc 213 Gene3D G3DSA:1.10.10.60 19 70 1.3E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS04635 a4da991884af10ca65de3463bc2cb0dc 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 48 71 3.2E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS04635 a4da991884af10ca65de3463bc2cb0dc 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 40 3.2E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS04635 a4da991884af10ca65de3463bc2cb0dc 213 Pfam PF16859 Bacterial transcriptional repressor C-terminal 85 199 2.6E-10 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS04635 a4da991884af10ca65de3463bc2cb0dc 213 SUPERFAMILY SSF46689 17 82 8.48E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS15855 017f5f2e9d104c140f8ea88cfce59fb2 260 Pfam PF00106 short chain dehydrogenase 8 200 2.6E-50 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15855 017f5f2e9d104c140f8ea88cfce59fb2 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 2.1E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15855 017f5f2e9d104c140f8ea88cfce59fb2 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 2.1E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15855 017f5f2e9d104c140f8ea88cfce59fb2 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 2.1E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15855 017f5f2e9d104c140f8ea88cfce59fb2 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 2.1E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15855 017f5f2e9d104c140f8ea88cfce59fb2 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 2.1E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15855 017f5f2e9d104c140f8ea88cfce59fb2 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 2.1E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15855 017f5f2e9d104c140f8ea88cfce59fb2 260 SUPERFAMILY SSF51735 2 259 1.23E-63 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS15855 017f5f2e9d104c140f8ea88cfce59fb2 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 3.3E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15855 017f5f2e9d104c140f8ea88cfce59fb2 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 3.3E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15855 017f5f2e9d104c140f8ea88cfce59fb2 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 3.3E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15855 017f5f2e9d104c140f8ea88cfce59fb2 260 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS15855 017f5f2e9d104c140f8ea88cfce59fb2 260 Gene3D G3DSA:3.40.50.720 1 260 5.6E-68 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS28385 cde5ce6c3f2c48e96f4160d51ff7b50f 119 Hamap MF_00227 Ribonuclease P protein component [rnpA]. 2 115 15.733 T 06-07-2017 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 BWK49_RS28385 cde5ce6c3f2c48e96f4160d51ff7b50f 119 Gene3D G3DSA:3.30.230.10 2 112 1.9E-28 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup BWK49_RS28385 cde5ce6c3f2c48e96f4160d51ff7b50f 119 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 5 112 1.1E-22 T 06-07-2017 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 BWK49_RS28385 cde5ce6c3f2c48e96f4160d51ff7b50f 119 Pfam PF00825 Ribonuclease P 2 112 1.0E-25 T 06-07-2017 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 BWK49_RS28385 cde5ce6c3f2c48e96f4160d51ff7b50f 119 ProSitePatterns PS00648 Bacterial ribonuclease P protein component signature. 55 69 - T 06-07-2017 IPR020539 Ribonuclease P, conserved site GO:0004526 BWK49_RS28385 cde5ce6c3f2c48e96f4160d51ff7b50f 119 SUPERFAMILY SSF54211 2 112 7.08E-23 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold BWK49_RS03920 91b11d105f30689b9d77585621408463 212 Pfam PF13483 Beta-lactamase superfamily domain 2 177 2.8E-19 T 06-07-2017 BWK49_RS03920 91b11d105f30689b9d77585621408463 212 SMART SM00849 7 177 5.2E-11 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS03920 91b11d105f30689b9d77585621408463 212 Gene3D G3DSA:3.60.15.10 1 183 1.5E-30 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS03920 91b11d105f30689b9d77585621408463 212 SUPERFAMILY SSF56281 1 183 9.83E-26 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS18465 0ca07091ce24a77f0110e579637ab256 274 SUPERFAMILY SSF51366 5 268 8.95E-60 T 06-07-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 BWK49_RS18465 0ca07091ce24a77f0110e579637ab256 274 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 90 103 - T 06-07-2017 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|Reactome: R-HSA-500753 BWK49_RS18465 0ca07091ce24a77f0110e579637ab256 274 Hamap MF_01215 Orotidine 5'-phosphate decarboxylase [pyrF]. 2 271 32.789 T 06-07-2017 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686 BWK49_RS18465 0ca07091ce24a77f0110e579637ab256 274 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 17 259 9.5E-44 T 06-07-2017 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|Reactome: R-HSA-500753 BWK49_RS18465 0ca07091ce24a77f0110e579637ab256 274 Gene3D G3DSA:3.20.20.70 7 267 3.6E-56 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 BWK49_RS18465 0ca07091ce24a77f0110e579637ab256 274 TIGRFAM TIGR02127 pyrF_sub2: orotidine 5'-phosphate decarboxylase 4 259 2.4E-84 T 06-07-2017 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686 BWK49_RS18465 0ca07091ce24a77f0110e579637ab256 274 SMART SM00934 17 261 7.0E-30 T 06-07-2017 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|Reactome: R-HSA-500753 BWK49_RS12330 f23e896bbe3e481eae7d8e81b08d9c71 248 Gene3D G3DSA:3.40.630.40 36 244 3.5E-33 T 06-07-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 BWK49_RS12330 f23e896bbe3e481eae7d8e81b08d9c71 248 SUPERFAMILY SSF53187 35 244 9.73E-32 T 06-07-2017 BWK49_RS12330 f23e896bbe3e481eae7d8e81b08d9c71 248 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 38 240 6.7E-31 T 06-07-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 BWK49_RS12330 f23e896bbe3e481eae7d8e81b08d9c71 248 SMART SM00646 119 240 1.3E-23 T 06-07-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 BWK49_RS17330 0cef4d8b9662f538d6b1a3821263780e 377 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 15 363 2.5E-100 T 06-07-2017 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 BWK49_RS17330 0cef4d8b9662f538d6b1a3821263780e 377 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 13 365 53.884 T 06-07-2017 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 BWK49_RS17330 0cef4d8b9662f538d6b1a3821263780e 377 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 228 237 - T 06-07-2017 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 BWK49_RS17330 0cef4d8b9662f538d6b1a3821263780e 377 Pfam PF00155 Aminotransferase class I and II 33 354 4.8E-56 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 BWK49_RS17330 0cef4d8b9662f538d6b1a3821263780e 377 Gene3D G3DSA:3.90.1150.10 272 364 2.2E-15 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 BWK49_RS17330 0cef4d8b9662f538d6b1a3821263780e 377 SUPERFAMILY SSF53383 32 361 4.95E-69 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase BWK49_RS17330 0cef4d8b9662f538d6b1a3821263780e 377 Gene3D G3DSA:3.40.640.10 51 271 5.6E-61 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 BWK49_RS06825 36facb0917df319de77d5054368b9817 50 Pfam PF13384 Homeodomain-like domain 9 48 5.8E-8 T 06-07-2017 BWK49_RS06825 36facb0917df319de77d5054368b9817 50 Gene3D G3DSA:1.10.10.60 10 49 7.3E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS06825 36facb0917df319de77d5054368b9817 50 SUPERFAMILY SSF46689 10 49 1.97E-7 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS25705 eb4aa5dd67512d26c40397ab623d1fa1 340 TIGRFAM TIGR03617 F420_MSMEG_2256: probable F420-dependent oxidoreductase, MSMEG_2256 family 18 334 7.8E-139 T 06-07-2017 IPR019919 Luciferase-like, F420-dependent oxidoreductase, MSMEG2256, predicted BWK49_RS25705 eb4aa5dd67512d26c40397ab623d1fa1 340 Gene3D G3DSA:3.20.20.30 4 329 7.7E-52 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS25705 eb4aa5dd67512d26c40397ab623d1fa1 340 Pfam PF00296 Luciferase-like monooxygenase 16 302 7.7E-48 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS25705 eb4aa5dd67512d26c40397ab623d1fa1 340 SUPERFAMILY SSF51679 9 324 3.53E-52 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS21125 324c816085d772df84d20a76e24acf65 143 Pfam PF01740 STAS domain 18 83 6.2E-9 T 06-07-2017 IPR002645 STAS domain BWK49_RS21125 324c816085d772df84d20a76e24acf65 143 SUPERFAMILY SSF52091 18 114 1.37E-10 T 06-07-2017 IPR002645 STAS domain BWK49_RS21125 324c816085d772df84d20a76e24acf65 143 Gene3D G3DSA:3.30.750.24 18 96 5.2E-11 T 06-07-2017 IPR002645 STAS domain BWK49_RS01505 d49c381493a8b27859e50482fbc718ad 259 Pfam PF09339 IclR helix-turn-helix domain 14 62 4.3E-9 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 BWK49_RS01505 d49c381493a8b27859e50482fbc718ad 259 Gene3D G3DSA:1.10.10.10 11 70 1.8E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS01505 d49c381493a8b27859e50482fbc718ad 259 SUPERFAMILY SSF55781 67 249 2.09E-39 T 06-07-2017 IPR029016 GAF domain-like BWK49_RS01505 d49c381493a8b27859e50482fbc718ad 259 SMART SM00346 9 99 1.3E-9 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 BWK49_RS01505 d49c381493a8b27859e50482fbc718ad 259 Pfam PF01614 Bacterial transcriptional regulator 128 243 4.1E-26 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal BWK49_RS01505 d49c381493a8b27859e50482fbc718ad 259 Gene3D G3DSA:3.30.450.40 85 249 5.2E-43 T 06-07-2017 IPR029016 GAF domain-like BWK49_RS01505 d49c381493a8b27859e50482fbc718ad 259 SUPERFAMILY SSF46785 13 80 6.07E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS04250 ac793c1fabbc1ab99d366784df134162 238 Gene3D G3DSA:3.40.50.300 3 232 1.1E-26 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS04250 ac793c1fabbc1ab99d366784df134162 238 SUPERFAMILY SSF52540 1 232 7.19E-19 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS04250 ac793c1fabbc1ab99d366784df134162 238 Pfam PF13614 AAA domain 2 30 6.0E-7 T 06-07-2017 IPR025669 AAA domain BWK49_RS24840 701c3ef65a2428e3820a6fed2a2fc87c 338 Gene3D G3DSA:1.10.600.10 18 336 1.4E-87 T 06-07-2017 IPR008949 Isoprenoid synthase domain BWK49_RS24840 701c3ef65a2428e3820a6fed2a2fc87c 338 SUPERFAMILY SSF48576 20 337 5.1E-80 T 06-07-2017 IPR008949 Isoprenoid synthase domain BWK49_RS24840 701c3ef65a2428e3820a6fed2a2fc87c 338 Pfam PF00348 Polyprenyl synthetase 43 288 1.4E-60 T 06-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 BWK49_RS24840 701c3ef65a2428e3820a6fed2a2fc87c 338 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 218 230 - T 06-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 BWK49_RS20080 fc607b77ccbd1c66a32572b8990bb18a 405 Pfam PF02163 Peptidase family M50 10 375 3.7E-52 T 06-07-2017 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033 BWK49_RS20080 fc607b77ccbd1c66a32572b8990bb18a 405 SMART SM00228 114 203 1.4E-4 T 06-07-2017 IPR001478 PDZ domain GO:0005515 BWK49_RS20080 fc607b77ccbd1c66a32572b8990bb18a 405 SUPERFAMILY SSF50156 99 210 1.17E-12 T 06-07-2017 IPR001478 PDZ domain GO:0005515 BWK49_RS20080 fc607b77ccbd1c66a32572b8990bb18a 405 Gene3D G3DSA:2.30.42.10 94 212 4.6E-19 T 06-07-2017 IPR001478 PDZ domain GO:0005515 BWK49_RS24400 0e3e0f0b93bdc04f060a0f04069247e8 395 SUPERFAMILY SSF51905 149 310 5.05E-31 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS24400 0e3e0f0b93bdc04f060a0f04069247e8 395 SUPERFAMILY SSF55424 319 391 1.51E-16 T 06-07-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 BWK49_RS24400 0e3e0f0b93bdc04f060a0f04069247e8 395 Pfam PF14759 Reductase C-terminal 323 391 2.8E-12 T 06-07-2017 IPR028202 Reductase, C-terminal BWK49_RS24400 0e3e0f0b93bdc04f060a0f04069247e8 395 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 149 174 6.6E-16 T 06-07-2017 BWK49_RS24400 0e3e0f0b93bdc04f060a0f04069247e8 395 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 235 249 6.6E-16 T 06-07-2017 BWK49_RS24400 0e3e0f0b93bdc04f060a0f04069247e8 395 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 393 395 6.6E-16 T 06-07-2017 BWK49_RS24400 0e3e0f0b93bdc04f060a0f04069247e8 395 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 274 281 6.6E-16 T 06-07-2017 BWK49_RS24400 0e3e0f0b93bdc04f060a0f04069247e8 395 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 10 32 6.6E-16 T 06-07-2017 BWK49_RS24400 0e3e0f0b93bdc04f060a0f04069247e8 395 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 11 303 8.6E-62 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS24400 0e3e0f0b93bdc04f060a0f04069247e8 395 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 1.7E-23 T 06-07-2017 BWK49_RS24400 0e3e0f0b93bdc04f060a0f04069247e8 395 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 149 167 1.7E-23 T 06-07-2017 BWK49_RS24400 0e3e0f0b93bdc04f060a0f04069247e8 395 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 105 123 1.7E-23 T 06-07-2017 BWK49_RS24400 0e3e0f0b93bdc04f060a0f04069247e8 395 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 234 250 1.7E-23 T 06-07-2017 BWK49_RS24400 0e3e0f0b93bdc04f060a0f04069247e8 395 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 259 281 1.7E-23 T 06-07-2017 BWK49_RS24400 0e3e0f0b93bdc04f060a0f04069247e8 395 SUPERFAMILY SSF51905 10 193 1.05E-42 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS24400 0e3e0f0b93bdc04f060a0f04069247e8 395 Gene3D G3DSA:3.50.50.60 10 108 2.3E-33 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS24400 0e3e0f0b93bdc04f060a0f04069247e8 395 Gene3D G3DSA:3.50.50.60 109 312 2.8E-47 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS24400 0e3e0f0b93bdc04f060a0f04069247e8 395 Gene3D G3DSA:3.30.390.30 323 391 1.3E-16 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 BWK49_RS07240 07680777dd18373013430544fe765dfb 403 Hamap MF_00242 Arginine deiminase [arcA]. 3 403 41.69 T 06-07-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 BWK49_RS07240 07680777dd18373013430544fe765dfb 403 Pfam PF02274 Amidinotransferase 20 400 5.9E-91 T 06-07-2017 BWK49_RS07240 07680777dd18373013430544fe765dfb 403 PRINTS PR01466 Bacterial arginine deiminase signature 4 24 1.9E-47 T 06-07-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 BWK49_RS07240 07680777dd18373013430544fe765dfb 403 PRINTS PR01466 Bacterial arginine deiminase signature 382 400 1.9E-47 T 06-07-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 BWK49_RS07240 07680777dd18373013430544fe765dfb 403 PRINTS PR01466 Bacterial arginine deiminase signature 155 173 1.9E-47 T 06-07-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 BWK49_RS07240 07680777dd18373013430544fe765dfb 403 PRINTS PR01466 Bacterial arginine deiminase signature 359 373 1.9E-47 T 06-07-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 BWK49_RS07240 07680777dd18373013430544fe765dfb 403 PRINTS PR01466 Bacterial arginine deiminase signature 183 198 1.9E-47 T 06-07-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 BWK49_RS07240 07680777dd18373013430544fe765dfb 403 PRINTS PR01466 Bacterial arginine deiminase signature 339 356 1.9E-47 T 06-07-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 BWK49_RS07240 07680777dd18373013430544fe765dfb 403 SUPERFAMILY SSF55909 6 402 1.57E-114 T 06-07-2017 BWK49_RS07240 07680777dd18373013430544fe765dfb 403 Gene3D G3DSA:3.75.10.10 5 69 1.2E-114 T 06-07-2017 BWK49_RS07240 07680777dd18373013430544fe765dfb 403 Gene3D G3DSA:3.75.10.10 155 403 1.2E-114 T 06-07-2017 BWK49_RS07240 07680777dd18373013430544fe765dfb 403 TIGRFAM TIGR01078 arcA: arginine deiminase 9 403 7.6E-157 T 06-07-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 BWK49_RS07240 07680777dd18373013430544fe765dfb 403 PIRSF PIRSF006356 2 403 5.8E-141 T 06-07-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 BWK49_RS27645 9825b8702816138c4ca43fb0d1c172f3 204 SUPERFAMILY SSF52833 12 168 3.17E-14 T 06-07-2017 IPR012336 Thioredoxin-like fold BWK49_RS27645 9825b8702816138c4ca43fb0d1c172f3 204 Gene3D G3DSA:3.40.30.10 11 166 7.1E-8 T 06-07-2017 IPR012336 Thioredoxin-like fold BWK49_RS27645 9825b8702816138c4ca43fb0d1c172f3 204 Pfam PF01323 DSBA-like thioredoxin domain 13 165 2.3E-6 T 06-07-2017 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 BWK49_RS10120 51c4cc1d31305c2e8b0aaae7759ba267 473 Pfam PF00668 Condensation domain 72 338 1.1E-9 T 06-07-2017 IPR001242 Condensation domain BWK49_RS10120 51c4cc1d31305c2e8b0aaae7759ba267 473 SUPERFAMILY SSF52777 41 212 4.34E-14 T 06-07-2017 BWK49_RS10120 51c4cc1d31305c2e8b0aaae7759ba267 473 SUPERFAMILY SSF52777 229 465 5.45E-20 T 06-07-2017 BWK49_RS07090 83940b246b864d4052c0ef9d3f2a5d1b 484 Gene3D G3DSA:2.40.10.10 275 398 6.6E-44 T 06-07-2017 BWK49_RS07090 83940b246b864d4052c0ef9d3f2a5d1b 484 Gene3D G3DSA:2.40.10.10 147 274 5.3E-28 T 06-07-2017 BWK49_RS07090 83940b246b864d4052c0ef9d3f2a5d1b 484 Pfam PF13180 PDZ domain 397 479 8.2E-14 T 06-07-2017 IPR001478 PDZ domain GO:0005515 BWK49_RS07090 83940b246b864d4052c0ef9d3f2a5d1b 484 SUPERFAMILY SSF50494 155 201 3.62E-53 T 06-07-2017 IPR009003 Peptidase S1, PA clan BWK49_RS07090 83940b246b864d4052c0ef9d3f2a5d1b 484 SUPERFAMILY SSF50494 229 392 3.62E-53 T 06-07-2017 IPR009003 Peptidase S1, PA clan BWK49_RS07090 83940b246b864d4052c0ef9d3f2a5d1b 484 Pfam PF13365 Trypsin-like peptidase domain 182 350 1.4E-33 T 06-07-2017 BWK49_RS07090 83940b246b864d4052c0ef9d3f2a5d1b 484 Gene3D G3DSA:2.30.42.10 399 482 1.6E-15 T 06-07-2017 IPR001478 PDZ domain GO:0005515 BWK49_RS07090 83940b246b864d4052c0ef9d3f2a5d1b 484 PRINTS PR00834 HtrA/DegQ protease family signature 426 438 2.1E-33 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 BWK49_RS07090 83940b246b864d4052c0ef9d3f2a5d1b 484 PRINTS PR00834 HtrA/DegQ protease family signature 321 338 2.1E-33 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 BWK49_RS07090 83940b246b864d4052c0ef9d3f2a5d1b 484 PRINTS PR00834 HtrA/DegQ protease family signature 343 360 2.1E-33 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 BWK49_RS07090 83940b246b864d4052c0ef9d3f2a5d1b 484 PRINTS PR00834 HtrA/DegQ protease family signature 191 203 2.1E-33 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 BWK49_RS07090 83940b246b864d4052c0ef9d3f2a5d1b 484 PRINTS PR00834 HtrA/DegQ protease family signature 280 304 2.1E-33 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 BWK49_RS07090 83940b246b864d4052c0ef9d3f2a5d1b 484 SMART SM00228 396 468 5.8E-8 T 06-07-2017 IPR001478 PDZ domain GO:0005515 BWK49_RS07090 83940b246b864d4052c0ef9d3f2a5d1b 484 SUPERFAMILY SSF50156 395 481 1.97E-14 T 06-07-2017 IPR001478 PDZ domain GO:0005515 BWK49_RS23340 3e3498ee9671cfb0cf1c5f2a290e04ab 392 Gene3D G3DSA:3.30.70.360 184 299 3.5E-26 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain BWK49_RS23340 3e3498ee9671cfb0cf1c5f2a290e04ab 392 SUPERFAMILY SSF53187 8 199 1.92E-70 T 06-07-2017 BWK49_RS23340 3e3498ee9671cfb0cf1c5f2a290e04ab 392 SUPERFAMILY SSF53187 300 385 1.92E-70 T 06-07-2017 BWK49_RS23340 3e3498ee9671cfb0cf1c5f2a290e04ab 392 Pfam PF01546 Peptidase family M20/M25/M40 75 384 9.0E-26 T 06-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 BWK49_RS23340 3e3498ee9671cfb0cf1c5f2a290e04ab 392 Gene3D G3DSA:3.40.630.10 4 180 9.0E-86 T 06-07-2017 BWK49_RS23340 3e3498ee9671cfb0cf1c5f2a290e04ab 392 Gene3D G3DSA:3.40.630.10 300 385 9.0E-86 T 06-07-2017 BWK49_RS23340 3e3498ee9671cfb0cf1c5f2a290e04ab 392 PIRSF PIRSF005962 6 389 2.6E-93 T 06-07-2017 IPR017439 Amidohydrolase GO:0016787 BWK49_RS23340 3e3498ee9671cfb0cf1c5f2a290e04ab 392 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 18 375 1.5E-95 T 06-07-2017 IPR017439 Amidohydrolase GO:0016787 BWK49_RS23340 3e3498ee9671cfb0cf1c5f2a290e04ab 392 SUPERFAMILY SSF55031 184 301 6.88E-19 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain BWK49_RS10265 00862998ae78cab2d49a2d043a1b381b 390 SMART SM00729 20 243 1.3E-58 T 06-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 BWK49_RS10265 00862998ae78cab2d49a2d043a1b381b 390 Gene3D G3DSA:3.80.30.20 23 258 4.8E-33 T 06-07-2017 IPR023404 Radical SAM, alpha/beta horseshoe BWK49_RS10265 00862998ae78cab2d49a2d043a1b381b 390 Pfam PF04055 Radical SAM superfamily 25 196 1.8E-17 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 BWK49_RS10265 00862998ae78cab2d49a2d043a1b381b 390 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 23 349 6.1E-77 T 06-07-2017 IPR004559 Coproporphyrinogen III oxidase, oxygen-independent related GO:0004109|GO:0005737|GO:0006779|GO:0055114 BWK49_RS10265 00862998ae78cab2d49a2d043a1b381b 390 SUPERFAMILY SSF102114 9 389 3.4E-111 T 06-07-2017 BWK49_RS00885 779d5241891f5d0732365d6f9497ce20 540 TIGRFAM TIGR03923 T7SS_EccE: type VII secretion protein EccE 14 337 2.2E-74 T 06-07-2017 IPR021368 Type VII secretion system protein EccE BWK49_RS00885 779d5241891f5d0732365d6f9497ce20 540 Pfam PF11203 Putative type VII ESX secretion system translocon, EccE 173 262 3.8E-17 T 06-07-2017 IPR021368 Type VII secretion system protein EccE BWK49_RS10725 e801ec1b8bb025740d252344cc13f8a9 454 SUPERFAMILY SSF140459 2 174 6.8E-63 T 06-07-2017 BWK49_RS10725 e801ec1b8bb025740d252344cc13f8a9 454 Pfam PF00823 PPE family 5 161 2.0E-61 T 06-07-2017 IPR000030 PPE family BWK49_RS10725 e801ec1b8bb025740d252344cc13f8a9 454 Pfam PF09851 Short C-terminal domain 426 452 1.0E-6 T 06-07-2017 IPR018649 SHOCT domain BWK49_RS10725 e801ec1b8bb025740d252344cc13f8a9 454 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 313 381 2.8E-11 T 06-07-2017 IPR022171 PPE family, C-terminal BWK49_RS27375 b639ee124dbfa55b18e0f37879753e34 296 Gene3D G3DSA:3.10.129.10 14 123 2.2E-16 T 06-07-2017 IPR029069 HotDog domain BWK49_RS27375 b639ee124dbfa55b18e0f37879753e34 296 SUPERFAMILY SSF54637 13 118 7.13E-18 T 06-07-2017 IPR029069 HotDog domain BWK49_RS27375 b639ee124dbfa55b18e0f37879753e34 296 Pfam PF13622 Thioesterase-like superfamily 49 280 2.6E-27 T 06-07-2017 BWK49_RS27375 b639ee124dbfa55b18e0f37879753e34 296 SUPERFAMILY SSF54637 130 282 2.14E-23 T 06-07-2017 IPR029069 HotDog domain BWK49_RS27375 b639ee124dbfa55b18e0f37879753e34 296 Gene3D G3DSA:3.10.129.10 132 282 1.7E-24 T 06-07-2017 IPR029069 HotDog domain BWK49_RS00275 b6be78474c10c0060a75deb7528efa8a 167 Gene3D G3DSA:1.10.10.10 13 151 1.2E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS00275 b6be78474c10c0060a75deb7528efa8a 167 PRINTS PR00598 Bacterial regulatory protein MarR family signature 95 111 1.2E-5 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 BWK49_RS00275 b6be78474c10c0060a75deb7528efa8a 167 PRINTS PR00598 Bacterial regulatory protein MarR family signature 125 145 1.2E-5 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 BWK49_RS00275 b6be78474c10c0060a75deb7528efa8a 167 PRINTS PR00598 Bacterial regulatory protein MarR family signature 76 91 1.2E-5 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 BWK49_RS00275 b6be78474c10c0060a75deb7528efa8a 167 SUPERFAMILY SSF46785 13 149 4.37E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS00275 b6be78474c10c0060a75deb7528efa8a 167 Pfam PF01047 MarR family 42 100 3.7E-17 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 BWK49_RS00275 b6be78474c10c0060a75deb7528efa8a 167 SMART SM00347 35 135 9.7E-19 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 BWK49_RS01860 77369032260783f4ec86cff1ba41e515 170 SUPERFAMILY SSF54427 4 170 9.04E-47 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS01860 77369032260783f4ec86cff1ba41e515 170 Pfam PF00866 Ring hydroxylating beta subunit 21 162 7.2E-47 T 06-07-2017 IPR000391 Ring-hydroxylating dioxygenase beta subunit GO:0003824|GO:0006725|GO:0055114 BWK49_RS01860 77369032260783f4ec86cff1ba41e515 170 Gene3D G3DSA:3.10.450.50 4 170 6.0E-66 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS22405 cefb60751f001c9c06957555d50b4a60 315 Gene3D G3DSA:3.30.70.270 177 310 2.3E-35 T 06-07-2017 BWK49_RS22405 cefb60751f001c9c06957555d50b4a60 315 SMART SM00267 165 315 1.4E-30 T 06-07-2017 IPR000160 GGDEF domain BWK49_RS22405 cefb60751f001c9c06957555d50b4a60 315 Pfam PF00990 Diguanylate cyclase, GGDEF domain 176 309 2.1E-29 T 06-07-2017 IPR000160 GGDEF domain BWK49_RS22405 cefb60751f001c9c06957555d50b4a60 315 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 174 309 3.2E-26 T 06-07-2017 IPR000160 GGDEF domain BWK49_RS22405 cefb60751f001c9c06957555d50b4a60 315 SUPERFAMILY SSF55073 181 309 1.33E-32 T 06-07-2017 IPR029787 Nucleotide cyclase BWK49_RS05495 b1d005b9b84e192708667ec67d38efd5 378 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 11 123 1.3E-20 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS05495 b1d005b9b84e192708667ec67d38efd5 378 Gene3D G3DSA:1.10.540.10 9 124 1.5E-23 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS05495 b1d005b9b84e192708667ec67d38efd5 378 SUPERFAMILY SSF47203 229 376 3.22E-33 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS05495 b1d005b9b84e192708667ec67d38efd5 378 Gene3D G3DSA:1.20.140.10 229 376 2.1E-33 T 06-07-2017 BWK49_RS05495 b1d005b9b84e192708667ec67d38efd5 378 SUPERFAMILY SSF56645 6 219 8.12E-38 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS05495 b1d005b9b84e192708667ec67d38efd5 378 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 228 376 6.4E-22 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS05495 b1d005b9b84e192708667ec67d38efd5 378 Gene3D G3DSA:2.40.110.10 129 219 2.8E-6 T 06-07-2017 BWK49_RS04805 e11a2d95987c3440c36f0d45adc5e7a8 600 Pfam PF13655 N-terminal domain of reverse transcriptase 15 94 4.4E-27 T 06-07-2017 IPR025960 Reverse transcriptase, N-terminal domain BWK49_RS04805 e11a2d95987c3440c36f0d45adc5e7a8 600 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 59 412 4.8E-101 T 06-07-2017 IPR030931 Group II intron reverse transcriptase/maturase BWK49_RS04805 e11a2d95987c3440c36f0d45adc5e7a8 600 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 114 335 1.1E-41 T 06-07-2017 IPR000477 Reverse transcriptase domain BWK49_RS04805 e11a2d95987c3440c36f0d45adc5e7a8 600 SUPERFAMILY SSF56672 77 371 2.17E-45 T 06-07-2017 BWK49_RS04805 e11a2d95987c3440c36f0d45adc5e7a8 600 Pfam PF08388 Group II intron, maturase-specific domain 357 434 4.4E-18 T 06-07-2017 IPR013597 Group II intron, maturase-specific BWK49_RS26760 0040af4614a59de054c2561131919e5a 418 SUPERFAMILY SSF140459 3 172 2.2E-66 T 06-07-2017 BWK49_RS26760 0040af4614a59de054c2561131919e5a 418 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 315 387 1.5E-9 T 06-07-2017 IPR022171 PPE family, C-terminal BWK49_RS26760 0040af4614a59de054c2561131919e5a 418 Pfam PF00823 PPE family 5 160 1.3E-64 T 06-07-2017 IPR000030 PPE family BWK49_RS25595 eb890833754d81fb70a5fe04a2cc65f6 576 Gene3D G3DSA:3.20.20.140 71 303 7.4E-88 T 06-07-2017 BWK49_RS25595 eb890833754d81fb70a5fe04a2cc65f6 576 Gene3D G3DSA:3.20.20.140 420 480 7.4E-88 T 06-07-2017 BWK49_RS25595 eb890833754d81fb70a5fe04a2cc65f6 576 SUPERFAMILY SSF51338 463 557 4.96E-7 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 BWK49_RS25595 eb890833754d81fb70a5fe04a2cc65f6 576 Gene3D G3DSA:2.30.40.10 3 70 5.6E-18 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 BWK49_RS25595 eb890833754d81fb70a5fe04a2cc65f6 576 Gene3D G3DSA:2.30.40.10 481 566 1.8E-9 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 BWK49_RS25595 eb890833754d81fb70a5fe04a2cc65f6 576 SUPERFAMILY SSF51338 3 67 1.58E-18 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 BWK49_RS25595 eb890833754d81fb70a5fe04a2cc65f6 576 Pfam PF07969 Amidohydrolase family 45 550 7.0E-57 T 06-07-2017 IPR013108 Amidohydrolase 3 BWK49_RS25595 eb890833754d81fb70a5fe04a2cc65f6 576 SUPERFAMILY SSF51556 57 311 9.52E-67 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS25595 eb890833754d81fb70a5fe04a2cc65f6 576 SUPERFAMILY SSF51556 360 497 9.52E-67 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS08820 0c9cdf390c9978456d322a36b7c49c9c 129 Gene3D G3DSA:3.10.180.10 4 126 2.9E-22 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS08820 0c9cdf390c9978456d322a36b7c49c9c 129 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 120 1.6E-8 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain BWK49_RS08820 0c9cdf390c9978456d322a36b7c49c9c 129 SUPERFAMILY SSF54593 4 125 6.6E-20 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS06705 79543ea3cab5ef75949e25c29745d951 431 TIGRFAM TIGR01798 cit_synth_I: citrate (Si)-synthase 16 425 8.6E-183 T 06-07-2017 IPR010953 Citrate synthase, type I GO:0004108|GO:0005737 BWK49_RS06705 79543ea3cab5ef75949e25c29745d951 431 Pfam PF00285 Citrate synthase, C-terminal domain 48 414 1.7E-138 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 BWK49_RS06705 79543ea3cab5ef75949e25c29745d951 431 SUPERFAMILY SSF48256 6 431 4.19E-161 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 BWK49_RS06705 79543ea3cab5ef75949e25c29745d951 431 Gene3D G3DSA:1.10.580.10 54 283 1.7E-99 T 06-07-2017 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 BWK49_RS06705 79543ea3cab5ef75949e25c29745d951 431 PIRSF PIRSF001369 39 431 5.3E-159 T 06-07-2017 IPR024176 Citrate synthase, bacterial-type BWK49_RS06705 79543ea3cab5ef75949e25c29745d951 431 Gene3D G3DSA:1.10.230.10 284 376 1.5E-37 T 06-07-2017 IPR016143 Citrate synthase-like, small alpha subdomain Reactome: R-HSA-163765|Reactome: R-HSA-75105 BWK49_RS06705 79543ea3cab5ef75949e25c29745d951 431 ProSitePatterns PS00480 Citrate synthase signature. 306 318 - T 06-07-2017 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 BWK49_RS06705 79543ea3cab5ef75949e25c29745d951 431 PRINTS PR00143 Citrate synthase signature 167 180 1.8E-54 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 BWK49_RS06705 79543ea3cab5ef75949e25c29745d951 431 PRINTS PR00143 Citrate synthase signature 299 319 1.8E-54 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 BWK49_RS06705 79543ea3cab5ef75949e25c29745d951 431 PRINTS PR00143 Citrate synthase signature 382 396 1.8E-54 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 BWK49_RS06705 79543ea3cab5ef75949e25c29745d951 431 PRINTS PR00143 Citrate synthase signature 221 236 1.8E-54 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 BWK49_RS06705 79543ea3cab5ef75949e25c29745d951 431 PRINTS PR00143 Citrate synthase signature 243 271 1.8E-54 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 BWK49_RS06705 79543ea3cab5ef75949e25c29745d951 431 PRINTS PR00143 Citrate synthase signature 362 378 1.8E-54 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 BWK49_RS20145 453c99340cbb107151d0a54f64136cca 279 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 46 275 3.9E-60 T 06-07-2017 BWK49_RS20145 453c99340cbb107151d0a54f64136cca 279 Gene3D G3DSA:3.40.50.720 32 276 1.9E-81 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS20145 453c99340cbb107151d0a54f64136cca 279 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 165 173 3.3E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS20145 453c99340cbb107151d0a54f64136cca 279 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 185 204 3.3E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS20145 453c99340cbb107151d0a54f64136cca 279 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 113 124 3.3E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS20145 453c99340cbb107151d0a54f64136cca 279 SUPERFAMILY SSF51735 36 276 3.61E-80 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS20145 453c99340cbb107151d0a54f64136cca 279 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 172 200 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS20145 453c99340cbb107151d0a54f64136cca 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 240 260 6.5E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS20145 453c99340cbb107151d0a54f64136cca 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 113 124 6.5E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS20145 453c99340cbb107151d0a54f64136cca 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 38 55 6.5E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS20145 453c99340cbb107151d0a54f64136cca 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 185 204 6.5E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS20145 453c99340cbb107151d0a54f64136cca 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 223 6.5E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS20145 453c99340cbb107151d0a54f64136cca 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 175 6.5E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS23235 e66e1a0910a1cfe3a76d525cdb98e0f9 450 TIGRFAM TIGR03251 LAT_fam: L-lysine 6-transaminase 22 446 2.0E-229 T 06-07-2017 IPR017657 L-lysine 6-transaminase GO:0017000|GO:0030170|GO:0045484 MetaCyc: PWY-5298 BWK49_RS23235 e66e1a0910a1cfe3a76d525cdb98e0f9 450 Gene3D G3DSA:3.90.1150.10 354 447 7.6E-25 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 BWK49_RS23235 e66e1a0910a1cfe3a76d525cdb98e0f9 450 Gene3D G3DSA:3.90.1150.10 41 76 7.6E-25 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 BWK49_RS23235 e66e1a0910a1cfe3a76d525cdb98e0f9 450 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 269 306 - T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 BWK49_RS23235 e66e1a0910a1cfe3a76d525cdb98e0f9 450 PIRSF PIRSF000521 11 449 1.7E-156 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 BWK49_RS23235 e66e1a0910a1cfe3a76d525cdb98e0f9 450 Pfam PF00202 Aminotransferase class-III 39 445 2.6E-74 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 BWK49_RS23235 e66e1a0910a1cfe3a76d525cdb98e0f9 450 SUPERFAMILY SSF53383 36 448 1.77E-86 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase BWK49_RS23235 e66e1a0910a1cfe3a76d525cdb98e0f9 450 Gene3D G3DSA:3.40.640.10 92 351 2.2E-64 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 BWK49_RS07590 fdbdc3ae57b179d660a059bfcb7de619 98 Gene3D G3DSA:1.10.287.1060 1 97 4.5E-12 T 06-07-2017 BWK49_RS07590 fdbdc3ae57b179d660a059bfcb7de619 98 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 5 93 9.2E-20 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like BWK49_RS07590 fdbdc3ae57b179d660a059bfcb7de619 98 SUPERFAMILY SSF140453 4 97 5.62E-19 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like BWK49_RS07590 fdbdc3ae57b179d660a059bfcb7de619 98 Pfam PF06013 Proteins of 100 residues with WXG 5 90 3.8E-19 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like BWK49_RS15245 fdbdc3ae57b179d660a059bfcb7de619 98 Gene3D G3DSA:1.10.287.1060 1 97 4.5E-12 T 06-07-2017 BWK49_RS15245 fdbdc3ae57b179d660a059bfcb7de619 98 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 5 93 9.2E-20 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like BWK49_RS15245 fdbdc3ae57b179d660a059bfcb7de619 98 SUPERFAMILY SSF140453 4 97 5.62E-19 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like BWK49_RS15245 fdbdc3ae57b179d660a059bfcb7de619 98 Pfam PF06013 Proteins of 100 residues with WXG 5 90 3.8E-19 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like BWK49_RS16655 d7a8402780daee8c1ec80788c5724804 588 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 536 1.0E-14 T 06-07-2017 IPR003395 RecF/RecN/SMC, N-terminal BWK49_RS16655 d7a8402780daee8c1ec80788c5724804 588 Gene3D G3DSA:3.40.50.300 1 213 5.6E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS16655 d7a8402780daee8c1ec80788c5724804 588 PIRSF PIRSF003128 1 586 4.3E-167 T 06-07-2017 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 BWK49_RS16655 d7a8402780daee8c1ec80788c5724804 588 SUPERFAMILY SSF52540 1 224 3.29E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS16655 d7a8402780daee8c1ec80788c5724804 588 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 582 5.0E-210 T 06-07-2017 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 BWK49_RS16655 d7a8402780daee8c1ec80788c5724804 588 Gene3D G3DSA:3.40.50.300 452 537 2.4E-6 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS16655 d7a8402780daee8c1ec80788c5724804 588 SUPERFAMILY SSF52540 5 50 1.62E-19 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS16655 d7a8402780daee8c1ec80788c5724804 588 SUPERFAMILY SSF52540 402 537 1.62E-19 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS02655 2477635be9a6809d262ebfbf2ee8394b 184 Gene3D G3DSA:3.40.50.880 3 180 1.3E-58 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like BWK49_RS02655 2477635be9a6809d262ebfbf2ee8394b 184 SUPERFAMILY SSF52317 7 178 2.15E-47 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like BWK49_RS02655 2477635be9a6809d262ebfbf2ee8394b 184 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 10 177 5.0E-48 T 06-07-2017 IPR006286 Peptidase C56, PfpI BWK49_RS02655 2477635be9a6809d262ebfbf2ee8394b 184 Pfam PF01965 DJ-1/PfpI family 8 177 2.7E-52 T 06-07-2017 IPR002818 DJ-1/PfpI BWK49_RS24240 7455dd3fb212208c06bfc562879dc751 132 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 132 31.402 T 06-07-2017 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 BWK49_RS24240 7455dd3fb212208c06bfc562879dc751 132 Gene3D G3DSA:3.30.1490.10 76 132 1.5E-28 T 06-07-2017 BWK49_RS24240 7455dd3fb212208c06bfc562879dc751 132 SUPERFAMILY SSF56047 3 132 9.55E-45 T 06-07-2017 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 BWK49_RS24240 7455dd3fb212208c06bfc562879dc751 132 Gene3D G3DSA:3.30.1370.30 2 72 5.5E-28 T 06-07-2017 BWK49_RS24240 7455dd3fb212208c06bfc562879dc751 132 ProSitePatterns PS00053 Ribosomal protein S8 signature. 102 119 - T 06-07-2017 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 BWK49_RS24240 7455dd3fb212208c06bfc562879dc751 132 Pfam PF00410 Ribosomal protein S8 5 132 3.1E-49 T 06-07-2017 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 BWK49_RS00835 72d403a3b2b4ec1272a2c9b47382e0db 216 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 60 2.9E-15 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS00835 72d403a3b2b4ec1272a2c9b47382e0db 216 Gene3D G3DSA:1.10.357.10 7 199 1.1E-32 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS00835 72d403a3b2b4ec1272a2c9b47382e0db 216 SUPERFAMILY SSF46689 7 81 9.75E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS17120 ed4ce38e8439275ccda4fd7beb6b1805 857 SUPERFAMILY SSF49879 217 291 6.31E-23 T 06-07-2017 IPR008984 SMAD/FHA domain GO:0005515 BWK49_RS17120 ed4ce38e8439275ccda4fd7beb6b1805 857 Pfam PF00498 FHA domain 222 283 3.2E-15 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 BWK49_RS17120 ed4ce38e8439275ccda4fd7beb6b1805 857 Pfam PF00498 FHA domain 19 82 9.3E-15 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 BWK49_RS17120 ed4ce38e8439275ccda4fd7beb6b1805 857 Gene3D G3DSA:2.60.200.20 6 83 7.2E-19 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 BWK49_RS17120 ed4ce38e8439275ccda4fd7beb6b1805 857 SMART SM00382 332 570 1.9E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS17120 ed4ce38e8439275ccda4fd7beb6b1805 857 Gene3D G3DSA:3.40.50.300 299 530 6.4E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS17120 ed4ce38e8439275ccda4fd7beb6b1805 857 SMART SM00240 18 68 3.4E-12 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 BWK49_RS17120 ed4ce38e8439275ccda4fd7beb6b1805 857 SMART SM00240 220 269 1.9E-13 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 BWK49_RS17120 ed4ce38e8439275ccda4fd7beb6b1805 857 ProSitePatterns PS00211 ABC transporters family signature. 442 456 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 BWK49_RS17120 ed4ce38e8439275ccda4fd7beb6b1805 857 SUPERFAMILY SSF52540 307 532 8.44E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS17120 ed4ce38e8439275ccda4fd7beb6b1805 857 Pfam PF01061 ABC-2 type transporter 585 805 1.5E-15 T 06-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 BWK49_RS17120 ed4ce38e8439275ccda4fd7beb6b1805 857 SUPERFAMILY SSF49879 7 93 4.59E-21 T 06-07-2017 IPR008984 SMAD/FHA domain GO:0005515 BWK49_RS17120 ed4ce38e8439275ccda4fd7beb6b1805 857 Gene3D G3DSA:2.60.200.20 217 290 1.2E-18 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 BWK49_RS17120 ed4ce38e8439275ccda4fd7beb6b1805 857 Pfam PF00005 ABC transporter 323 470 2.7E-31 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 BWK49_RS05845 083c7a1894345fea6c40fd0c990b6028 288 TIGRFAM TIGR01250 pro_imino_pep_2: proline-specific peptidase 2 284 3.0E-100 T 06-07-2017 IPR005945 Proline-specific peptidase GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 BWK49_RS05845 083c7a1894345fea6c40fd0c990b6028 288 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 52 63 1.9E-13 T 06-07-2017 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 BWK49_RS05845 083c7a1894345fea6c40fd0c990b6028 288 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 95 109 1.9E-13 T 06-07-2017 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 BWK49_RS05845 083c7a1894345fea6c40fd0c990b6028 288 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 26 34 1.9E-13 T 06-07-2017 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 BWK49_RS05845 083c7a1894345fea6c40fd0c990b6028 288 Pfam PF00561 alpha/beta hydrolase fold 25 272 1.1E-17 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS05845 083c7a1894345fea6c40fd0c990b6028 288 SUPERFAMILY SSF53474 7 283 5.92E-55 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS05845 083c7a1894345fea6c40fd0c990b6028 288 Gene3D G3DSA:3.40.50.1820 4 286 5.2E-49 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS05845 083c7a1894345fea6c40fd0c990b6028 288 PIRSF PIRSF005539 1 288 3.9E-103 T 06-07-2017 IPR005945 Proline-specific peptidase GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 BWK49_RS03180 d482e4575a65608b6e6efe3f25afa69e 162 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 9 159 9.7E-51 T 06-07-2017 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 BWK49_RS03180 d482e4575a65608b6e6efe3f25afa69e 162 SUPERFAMILY SSF69765 8 159 2.09E-49 T 06-07-2017 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 BWK49_RS03180 d482e4575a65608b6e6efe3f25afa69e 162 Pfam PF02542 YgbB family 9 158 1.4E-45 T 06-07-2017 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 BWK49_RS03180 d482e4575a65608b6e6efe3f25afa69e 162 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 8 160 30.9 T 06-07-2017 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 BWK49_RS03180 d482e4575a65608b6e6efe3f25afa69e 162 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 42 57 - T 06-07-2017 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 BWK49_RS03180 d482e4575a65608b6e6efe3f25afa69e 162 Gene3D G3DSA:3.30.1330.50 8 159 3.5E-53 T 06-07-2017 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 BWK49_RS13005 67ef64974e87b3b2b24ff83dcd86b839 349 SUPERFAMILY SSF48576 6 348 5.76E-73 T 06-07-2017 IPR008949 Isoprenoid synthase domain BWK49_RS13005 67ef64974e87b3b2b24ff83dcd86b839 349 Gene3D G3DSA:1.10.600.10 5 348 5.0E-79 T 06-07-2017 IPR008949 Isoprenoid synthase domain BWK49_RS13005 67ef64974e87b3b2b24ff83dcd86b839 349 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 81 95 - T 06-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 BWK49_RS13005 67ef64974e87b3b2b24ff83dcd86b839 349 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 225 237 - T 06-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 BWK49_RS13005 67ef64974e87b3b2b24ff83dcd86b839 349 Pfam PF00348 Polyprenyl synthetase 32 285 8.4E-47 T 06-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 BWK49_RS08100 cdb557e1c56d00c7fde84f27b774a41a 404 Gene3D G3DSA:1.10.630.10 13 403 7.4E-121 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS08100 cdb557e1c56d00c7fde84f27b774a41a 404 SUPERFAMILY SSF48264 20 403 3.41E-95 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS08100 cdb557e1c56d00c7fde84f27b774a41a 404 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 344 353 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 BWK49_RS08100 cdb557e1c56d00c7fde84f27b774a41a 404 Pfam PF00067 Cytochrome P450 51 386 4.9E-25 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS08100 cdb557e1c56d00c7fde84f27b774a41a 404 PRINTS PR00359 B-class P450 signature 141 157 4.2E-51 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS08100 cdb557e1c56d00c7fde84f27b774a41a 404 PRINTS PR00359 B-class P450 signature 293 320 4.2E-51 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS08100 cdb557e1c56d00c7fde84f27b774a41a 404 PRINTS PR00359 B-class P450 signature 342 351 4.2E-51 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS08100 cdb557e1c56d00c7fde84f27b774a41a 404 PRINTS PR00359 B-class P450 signature 351 362 4.2E-51 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS08100 cdb557e1c56d00c7fde84f27b774a41a 404 PRINTS PR00359 B-class P450 signature 94 105 4.2E-51 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS08100 cdb557e1c56d00c7fde84f27b774a41a 404 PRINTS PR00359 B-class P450 signature 276 287 4.2E-51 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS08100 cdb557e1c56d00c7fde84f27b774a41a 404 PRINTS PR00359 B-class P450 signature 321 336 4.2E-51 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS08100 cdb557e1c56d00c7fde84f27b774a41a 404 PRINTS PR00359 B-class P450 signature 195 217 4.2E-51 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS08100 cdb557e1c56d00c7fde84f27b774a41a 404 PRINTS PR00359 B-class P450 signature 158 173 4.2E-51 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS10070 1aa5392e35efc57f4f2db17b75d65b93 131 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 4 109 22.619 T 06-07-2017 IPR004394 Protein Iojap/ribosomal silencing factor RsfS BWK49_RS10070 1aa5392e35efc57f4f2db17b75d65b93 131 Gene3D G3DSA:3.30.460.10 8 112 3.6E-35 T 06-07-2017 BWK49_RS10070 1aa5392e35efc57f4f2db17b75d65b93 131 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 14 108 1.8E-31 T 06-07-2017 IPR004394 Protein Iojap/ribosomal silencing factor RsfS BWK49_RS10070 1aa5392e35efc57f4f2db17b75d65b93 131 SUPERFAMILY SSF81301 7 117 1.96E-37 T 06-07-2017 BWK49_RS10070 1aa5392e35efc57f4f2db17b75d65b93 131 Pfam PF02410 Ribosomal silencing factor during starvation 16 108 2.0E-24 T 06-07-2017 BWK49_RS14420 03cc02be39b8f0c254deb318cafed86a 458 Gene3D G3DSA:1.10.3140.10 1 75 2.2E-11 T 06-07-2017 BWK49_RS14420 03cc02be39b8f0c254deb318cafed86a 458 Pfam PF11794 4-hydroxyphenylacetate 3-hydroxylase N terminal 3 249 6.9E-63 T 06-07-2017 IPR024674 HpaB/PvcC/4-BUDH N-terminal BWK49_RS14420 03cc02be39b8f0c254deb318cafed86a 458 PIRSF PIRSF000331 1 457 8.4E-95 T 06-07-2017 IPR004925 HpaB/PvcC/4-BUDH BWK49_RS14420 03cc02be39b8f0c254deb318cafed86a 458 Pfam PF03241 4-hydroxyphenylacetate 3-hydroxylase C terminal 263 454 1.4E-48 T 06-07-2017 IPR024719 HpaB/PvcC/4-BUDH C-terminal BWK49_RS14420 03cc02be39b8f0c254deb318cafed86a 458 SUPERFAMILY SSF47203 241 456 2.72E-49 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS14420 03cc02be39b8f0c254deb318cafed86a 458 Gene3D G3DSA:2.40.110.10 126 241 7.3E-43 T 06-07-2017 BWK49_RS14420 03cc02be39b8f0c254deb318cafed86a 458 Gene3D G3DSA:1.20.140.10 242 455 1.5E-58 T 06-07-2017 BWK49_RS14420 03cc02be39b8f0c254deb318cafed86a 458 SUPERFAMILY SSF56645 1 249 1.83E-58 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS16975 b6f4c0e1a0d336b112fb390a455f4314 347 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 164 318 3.7E-24 T 06-07-2017 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 BWK49_RS16975 b6f4c0e1a0d336b112fb390a455f4314 347 SUPERFAMILY SSF55347 153 315 1.42E-45 T 06-07-2017 BWK49_RS16975 b6f4c0e1a0d336b112fb390a455f4314 347 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 6 136 2.8E-21 T 06-07-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 BWK49_RS16975 b6f4c0e1a0d336b112fb390a455f4314 347 Gene3D G3DSA:3.30.360.10 162 315 1.3E-55 T 06-07-2017 BWK49_RS16975 b6f4c0e1a0d336b112fb390a455f4314 347 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 5 347 3.8E-114 T 06-07-2017 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 BWK49_RS16975 b6f4c0e1a0d336b112fb390a455f4314 347 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 148 164 - T 06-07-2017 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 BWK49_RS16975 b6f4c0e1a0d336b112fb390a455f4314 347 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 5 341 38.278 T 06-07-2017 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 BWK49_RS16975 b6f4c0e1a0d336b112fb390a455f4314 347 Gene3D G3DSA:3.40.50.720 3 161 2.3E-51 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS16975 b6f4c0e1a0d336b112fb390a455f4314 347 SUPERFAMILY SSF51735 5 178 3.08E-42 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS16975 b6f4c0e1a0d336b112fb390a455f4314 347 SMART SM00859 6 143 2.1E-42 T 06-07-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 BWK49_RS14965 841b1db94c2bf0d651d2f65e741c3a13 225 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 219 1.1E-18 T 06-07-2017 BWK49_RS14965 841b1db94c2bf0d651d2f65e741c3a13 225 SUPERFAMILY SSF51735 5 222 1.68E-33 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS14965 841b1db94c2bf0d651d2f65e741c3a13 225 Gene3D G3DSA:3.40.50.720 5 221 1.6E-30 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS22870 7445e7838a5a08dcabff0bfb8bc6da3b 384 SUPERFAMILY SSF52343 165 292 2.23E-25 T 06-07-2017 BWK49_RS22870 7445e7838a5a08dcabff0bfb8bc6da3b 384 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 310 375 6.7E-10 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 BWK49_RS22870 7445e7838a5a08dcabff0bfb8bc6da3b 384 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 109 116 8.0E-5 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 BWK49_RS22870 7445e7838a5a08dcabff0bfb8bc6da3b 384 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 90 100 8.0E-5 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 BWK49_RS22870 7445e7838a5a08dcabff0bfb8bc6da3b 384 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 176 195 8.0E-5 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 BWK49_RS22870 7445e7838a5a08dcabff0bfb8bc6da3b 384 SUPERFAMILY SSF54292 284 384 3.01E-22 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 BWK49_RS22870 7445e7838a5a08dcabff0bfb8bc6da3b 384 SUPERFAMILY SSF63380 56 165 5.45E-21 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 BWK49_RS22870 7445e7838a5a08dcabff0bfb8bc6da3b 384 Gene3D G3DSA:3.10.20.30 285 383 1.7E-23 T 06-07-2017 IPR012675 Beta-grasp domain BWK49_RS22870 7445e7838a5a08dcabff0bfb8bc6da3b 384 Pfam PF00970 Oxidoreductase FAD-binding domain 72 165 2.8E-8 T 06-07-2017 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 BWK49_RS22870 7445e7838a5a08dcabff0bfb8bc6da3b 384 Gene3D G3DSA:2.40.30.10 60 158 4.3E-26 T 06-07-2017 BWK49_RS22870 7445e7838a5a08dcabff0bfb8bc6da3b 384 Pfam PF00175 Oxidoreductase NAD-binding domain 177 273 1.6E-8 T 06-07-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 BWK49_RS22870 7445e7838a5a08dcabff0bfb8bc6da3b 384 Gene3D G3DSA:3.40.50.80 159 284 8.2E-25 T 06-07-2017 BWK49_RS02100 afc4e81f262e6fb40b40ff7e738bb5e3 234 SMART SM00448 9 120 2.9E-43 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 BWK49_RS02100 afc4e81f262e6fb40b40ff7e738bb5e3 234 Gene3D G3DSA:1.10.10.10 135 232 4.4E-34 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS02100 afc4e81f262e6fb40b40ff7e738bb5e3 234 SUPERFAMILY SSF52172 7 187 2.42E-41 T 06-07-2017 IPR011006 CheY-like superfamily BWK49_RS02100 afc4e81f262e6fb40b40ff7e738bb5e3 234 Pfam PF00486 Transcriptional regulatory protein, C terminal 156 230 2.3E-24 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 BWK49_RS02100 afc4e81f262e6fb40b40ff7e738bb5e3 234 SMART SM00862 156 230 1.4E-25 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 BWK49_RS02100 afc4e81f262e6fb40b40ff7e738bb5e3 234 Pfam PF00072 Response regulator receiver domain 11 120 5.8E-29 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 BWK49_RS02100 afc4e81f262e6fb40b40ff7e738bb5e3 234 Gene3D G3DSA:3.40.50.2300 2 128 2.0E-40 T 06-07-2017 BWK49_RS28775 212b1b4a975264036b958cc553be02f9 548 Pfam PF02195 ParB-like nuclease domain 25 101 7.7E-9 T 06-07-2017 IPR003115 ParB/Sulfiredoxin BWK49_RS28775 212b1b4a975264036b958cc553be02f9 548 SUPERFAMILY SSF110849 38 102 7.67E-9 T 06-07-2017 IPR003115 ParB/Sulfiredoxin BWK49_RS28775 212b1b4a975264036b958cc553be02f9 548 SMART SM00470 22 107 2.9E-6 T 06-07-2017 IPR003115 ParB/Sulfiredoxin BWK49_RS28775 212b1b4a975264036b958cc553be02f9 548 SUPERFAMILY SSF109709 111 216 3.27E-7 T 06-07-2017 BWK49_RS28775 212b1b4a975264036b958cc553be02f9 548 Gene3D G3DSA:3.90.1530.10 44 105 6.4E-7 T 06-07-2017 BWK49_RS22235 982e69097e5fb17f24f4fe38947875b1 597 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 426 445 - T 06-07-2017 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 BWK49_RS22235 982e69097e5fb17f24f4fe38947875b1 597 Gene3D G3DSA:3.40.50.1220 193 354 1.6E-38 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain BWK49_RS22235 982e69097e5fb17f24f4fe38947875b1 597 SUPERFAMILY SSF52518 6 181 1.02E-50 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS22235 982e69097e5fb17f24f4fe38947875b1 597 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 199 329 2.0E-23 T 06-07-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 BWK49_RS22235 982e69097e5fb17f24f4fe38947875b1 597 SUPERFAMILY SSF52518 365 565 4.83E-52 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS22235 982e69097e5fb17f24f4fe38947875b1 597 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 389 544 6.4E-27 T 06-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 BWK49_RS22235 982e69097e5fb17f24f4fe38947875b1 597 SUPERFAMILY SSF52467 157 358 2.45E-41 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain BWK49_RS22235 982e69097e5fb17f24f4fe38947875b1 597 Gene3D G3DSA:3.40.50.970 364 564 1.6E-52 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS22235 982e69097e5fb17f24f4fe38947875b1 597 Gene3D G3DSA:3.40.50.970 2 181 1.3E-59 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS22235 982e69097e5fb17f24f4fe38947875b1 597 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 5 173 5.4E-48 T 06-07-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 BWK49_RS00775 5539d5539a66090128fad5fdcdf2916a 297 Gene3D G3DSA:1.10.10.10 167 266 4.0E-5 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS07045 5841f0c987c83e1c0c5155ff98ea7df5 388 SUPERFAMILY SSF47203 231 386 1.3E-38 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS07045 5841f0c987c83e1c0c5155ff98ea7df5 388 Gene3D G3DSA:2.40.110.10 124 221 1.2E-29 T 06-07-2017 BWK49_RS07045 5841f0c987c83e1c0c5155ff98ea7df5 388 Gene3D G3DSA:1.10.540.10 6 120 1.7E-30 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS07045 5841f0c987c83e1c0c5155ff98ea7df5 388 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 239 379 2.9E-30 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS07045 5841f0c987c83e1c0c5155ff98ea7df5 388 SUPERFAMILY SSF56645 5 244 5.24E-63 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS07045 5841f0c987c83e1c0c5155ff98ea7df5 388 Gene3D G3DSA:1.20.140.10 222 387 1.3E-46 T 06-07-2017 BWK49_RS07045 5841f0c987c83e1c0c5155ff98ea7df5 388 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 124 204 3.0E-19 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 BWK49_RS07045 5841f0c987c83e1c0c5155ff98ea7df5 388 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 119 8.5E-28 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS09195 6f0e44049aaeffd68631d6060e2c9a51 397 PIRSF PIRSF016578 2 374 4.5E-13 T 06-07-2017 BWK49_RS09195 6f0e44049aaeffd68631d6060e2c9a51 397 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 238 383 8.8E-42 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS09195 6f0e44049aaeffd68631d6060e2c9a51 397 Gene3D G3DSA:2.40.110.10 127 224 1.8E-37 T 06-07-2017 BWK49_RS09195 6f0e44049aaeffd68631d6060e2c9a51 397 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 12 123 2.6E-26 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS09195 6f0e44049aaeffd68631d6060e2c9a51 397 Gene3D G3DSA:1.20.140.10 225 390 3.8E-53 T 06-07-2017 BWK49_RS09195 6f0e44049aaeffd68631d6060e2c9a51 397 Gene3D G3DSA:1.10.540.10 11 124 5.2E-28 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS09195 6f0e44049aaeffd68631d6060e2c9a51 397 SUPERFAMILY SSF56645 10 247 9.03E-71 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS09195 6f0e44049aaeffd68631d6060e2c9a51 397 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 127 223 2.4E-27 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 BWK49_RS09195 6f0e44049aaeffd68631d6060e2c9a51 397 SUPERFAMILY SSF47203 237 386 1.34E-46 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS16795 fa3754c7313cee862006f2801a11ff7d 236 Pfam PF00857 Isochorismatase family 28 202 3.2E-24 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 BWK49_RS16795 fa3754c7313cee862006f2801a11ff7d 236 SUPERFAMILY SSF52499 19 232 3.53E-33 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 BWK49_RS16795 fa3754c7313cee862006f2801a11ff7d 236 Gene3D G3DSA:3.40.50.850 17 234 3.6E-34 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 BWK49_RS03375 4b71fbc10d2809958b57204419bf7c87 252 SUPERFAMILY SSF51735 7 236 1.95E-70 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS03375 4b71fbc10d2809958b57204419bf7c87 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 126 134 3.8E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS03375 4b71fbc10d2809958b57204419bf7c87 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 165 3.8E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS03375 4b71fbc10d2809958b57204419bf7c87 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 72 83 3.8E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS03375 4b71fbc10d2809958b57204419bf7c87 252 Gene3D G3DSA:3.40.50.720 4 236 3.8E-69 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS03375 4b71fbc10d2809958b57204419bf7c87 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 5.9E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS03375 4b71fbc10d2809958b57204419bf7c87 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 5.9E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS03375 4b71fbc10d2809958b57204419bf7c87 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 146 165 5.9E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS03375 4b71fbc10d2809958b57204419bf7c87 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 183 5.9E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS03375 4b71fbc10d2809958b57204419bf7c87 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 201 221 5.9E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS03375 4b71fbc10d2809958b57204419bf7c87 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 120 136 5.9E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS03375 4b71fbc10d2809958b57204419bf7c87 252 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 133 161 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS03375 4b71fbc10d2809958b57204419bf7c87 252 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 236 2.7E-53 T 06-07-2017 BWK49_RS17785 41a987118dbdb1516fbdaf43021f1874 749 Pfam PF02310 B12 binding domain 618 732 3.5E-15 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 BWK49_RS17785 41a987118dbdb1516fbdaf43021f1874 749 Pfam PF01642 Methylmalonyl-CoA mutase 52 576 5.1E-229 T 06-07-2017 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 BWK49_RS17785 41a987118dbdb1516fbdaf43021f1874 749 Gene3D G3DSA:3.40.50.280 582 744 3.4E-72 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 BWK49_RS17785 41a987118dbdb1516fbdaf43021f1874 749 SUPERFAMILY SSF52242 582 746 9.03E-59 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 BWK49_RS17785 41a987118dbdb1516fbdaf43021f1874 749 SUPERFAMILY SSF51703 27 578 4.71E-212 T 06-07-2017 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 BWK49_RS17785 41a987118dbdb1516fbdaf43021f1874 749 ProSitePatterns PS00544 Methylmalonyl-CoA mutase signature. 397 422 - T 06-07-2017 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 BWK49_RS17785 41a987118dbdb1516fbdaf43021f1874 749 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 50 583 2.0E-283 T 06-07-2017 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 BWK49_RS17785 41a987118dbdb1516fbdaf43021f1874 749 Gene3D G3DSA:3.20.20.240 49 521 1.8E-202 T 06-07-2017 IPR014348 Cobalamin (vitamin B12)-dependent enzyme, catalytic subdomain GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 BWK49_RS17785 41a987118dbdb1516fbdaf43021f1874 749 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 615 744 2.0E-63 T 06-07-2017 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 BWK49_RS07850 89bfafddc47ccc37b8689cf563d1cf44 1093 Gene3D G3DSA:3.30.300.30 454 567 1.2E-36 T 06-07-2017 BWK49_RS07850 89bfafddc47ccc37b8689cf563d1cf44 1093 ProSitePatterns PS00455 Putative AMP-binding domain signature. 196 207 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS07850 89bfafddc47ccc37b8689cf563d1cf44 1093 Gene3D G3DSA:2.30.38.10 368 449 6.4E-24 T 06-07-2017 BWK49_RS07850 89bfafddc47ccc37b8689cf563d1cf44 1093 Gene3D G3DSA:3.40.50.980 52 204 2.5E-45 T 06-07-2017 BWK49_RS07850 89bfafddc47ccc37b8689cf563d1cf44 1093 SUPERFAMILY SSF56801 19 576 9.81E-145 T 06-07-2017 BWK49_RS07850 89bfafddc47ccc37b8689cf563d1cf44 1093 Gene3D G3DSA:3.40.50.980 205 367 3.5E-41 T 06-07-2017 BWK49_RS07850 89bfafddc47ccc37b8689cf563d1cf44 1093 Gene3D G3DSA:1.10.1200.10 568 627 5.5E-24 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS07850 89bfafddc47ccc37b8689cf563d1cf44 1093 Pfam PF00550 Phosphopantetheine attachment site 565 625 8.8E-10 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS07850 89bfafddc47ccc37b8689cf563d1cf44 1093 ProSitePatterns PS00012 Phosphopantetheine attachment site. 587 602 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site BWK49_RS07850 89bfafddc47ccc37b8689cf563d1cf44 1093 SUPERFAMILY SSF47336 555 625 9.55E-17 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS07850 89bfafddc47ccc37b8689cf563d1cf44 1093 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 78 483 4.0E-132 T 06-07-2017 IPR010071 Amino acid adenylation domain BWK49_RS07850 89bfafddc47ccc37b8689cf563d1cf44 1093 Pfam PF00668 Condensation domain 661 933 5.5E-22 T 06-07-2017 IPR001242 Condensation domain BWK49_RS07850 89bfafddc47ccc37b8689cf563d1cf44 1093 Pfam PF13193 AMP-binding enzyme C-terminal domain 467 538 3.2E-9 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS07850 89bfafddc47ccc37b8689cf563d1cf44 1093 Pfam PF00501 AMP-binding enzyme 57 459 1.3E-90 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS07850 89bfafddc47ccc37b8689cf563d1cf44 1093 SUPERFAMILY SSF52777 823 1081 4.11E-22 T 06-07-2017 BWK49_RS07850 89bfafddc47ccc37b8689cf563d1cf44 1093 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 953 1092 1.6E-25 T 06-07-2017 IPR010060 Non-ribosomal peptide synthase BWK49_RS07850 89bfafddc47ccc37b8689cf563d1cf44 1093 SUPERFAMILY SSF52777 641 830 1.67E-24 T 06-07-2017 BWK49_RS09140 c46da4d1db3ead212ce0a9969b74d9ad 203 Gene3D G3DSA:3.90.950.10 2 197 5.6E-75 T 06-07-2017 IPR029001 Inosine triphosphate pyrophosphatase-like BWK49_RS09140 c46da4d1db3ead212ce0a9969b74d9ad 203 Pfam PF01725 Ham1 family 4 192 2.1E-51 T 06-07-2017 IPR002637 Ham1-like protein GO:0016787 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206|Reactome: R-HSA-15869 BWK49_RS09140 c46da4d1db3ead212ce0a9969b74d9ad 203 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 4 192 5.4E-46 T 06-07-2017 IPR002637 Ham1-like protein GO:0016787 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206|Reactome: R-HSA-15869 BWK49_RS09140 c46da4d1db3ead212ce0a9969b74d9ad 203 Hamap MF_01405 dITP/XTP pyrophosphatase [rdgB]. 2 197 46.974 T 06-07-2017 IPR020922 Non-canonical purine NTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206 BWK49_RS09140 c46da4d1db3ead212ce0a9969b74d9ad 203 SUPERFAMILY SSF52972 2 196 3.4E-60 T 06-07-2017 IPR029001 Inosine triphosphate pyrophosphatase-like BWK49_RS16995 0ea0cae128cd22c05b46b9b6aeec2de3 306 Gene3D G3DSA:3.30.70.1230 117 255 2.3E-26 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 BWK49_RS16995 0ea0cae128cd22c05b46b9b6aeec2de3 306 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 118 252 4.1E-13 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 BWK49_RS16995 0ea0cae128cd22c05b46b9b6aeec2de3 306 SMART SM00044 73 275 2.3E-21 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 BWK49_RS16995 0ea0cae128cd22c05b46b9b6aeec2de3 306 SUPERFAMILY SSF55073 114 257 5.18E-37 T 06-07-2017 IPR029787 Nucleotide cyclase BWK49_RS13235 940743af7fa13fc18a3bf5157202d0f6 2116 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 556 851 4.7E-86 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain BWK49_RS13235 940743af7fa13fc18a3bf5157202d0f6 2116 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 284 397 6.8E-36 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal BWK49_RS13235 940743af7fa13fc18a3bf5157202d0f6 2116 SUPERFAMILY SSF55048 677 741 7.85E-7 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 BWK49_RS13235 940743af7fa13fc18a3bf5157202d0f6 2116 SMART SM00825 Beta-ketoacyl synthase 29 451 5.5E-183 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain BWK49_RS13235 940743af7fa13fc18a3bf5157202d0f6 2116 Pfam PF14765 Polyketide synthase dehydratase 915 1189 3.1E-56 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS13235 940743af7fa13fc18a3bf5157202d0f6 2116 Gene3D G3DSA:3.40.366.10 741 849 1.9E-64 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 BWK49_RS13235 940743af7fa13fc18a3bf5157202d0f6 2116 Gene3D G3DSA:3.40.366.10 551 672 1.9E-64 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 BWK49_RS13235 940743af7fa13fc18a3bf5157202d0f6 2116 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 28 276 4.2E-91 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal BWK49_RS13235 940743af7fa13fc18a3bf5157202d0f6 2116 SUPERFAMILY SSF47336 2033 2114 1.14E-13 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS13235 940743af7fa13fc18a3bf5157202d0f6 2116 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 1452 1518 2.2E-5 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 BWK49_RS13235 940743af7fa13fc18a3bf5157202d0f6 2116 Gene3D G3DSA:3.40.50.720 1770 1983 7.0E-33 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS13235 940743af7fa13fc18a3bf5157202d0f6 2116 Gene3D G3DSA:3.40.47.10 289 452 9.9E-51 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS13235 940743af7fa13fc18a3bf5157202d0f6 2116 Pfam PF08659 KR domain 1771 1952 1.9E-55 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS13235 940743af7fa13fc18a3bf5157202d0f6 2116 SUPERFAMILY SSF51735 1540 1694 6.5E-39 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS13235 940743af7fa13fc18a3bf5157202d0f6 2116 Pfam PF00550 Phosphopantetheine attachment site 2040 2106 7.3E-11 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS13235 940743af7fa13fc18a3bf5157202d0f6 2116 SUPERFAMILY SSF51735 1769 1994 4.32E-38 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS13235 940743af7fa13fc18a3bf5157202d0f6 2116 Gene3D G3DSA:3.90.180.10 1429 1569 5.9E-42 T 06-07-2017 IPR011032 GroES-like BWK49_RS13235 940743af7fa13fc18a3bf5157202d0f6 2116 SUPERFAMILY SSF53901 26 396 8.65E-94 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS13235 940743af7fa13fc18a3bf5157202d0f6 2116 Gene3D G3DSA:1.10.1200.10 2039 2111 1.9E-14 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS13235 940743af7fa13fc18a3bf5157202d0f6 2116 Gene3D G3DSA:3.40.50.720 1570 1663 1.8E-23 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS13235 940743af7fa13fc18a3bf5157202d0f6 2116 SMART SM00826 915 1075 1.7E-40 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS13235 940743af7fa13fc18a3bf5157202d0f6 2116 Gene3D G3DSA:3.40.47.10 29 288 4.4E-92 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS13235 940743af7fa13fc18a3bf5157202d0f6 2116 SMART SM00823 Phosphopantetheine attachment site 2042 2110 1.2E-12 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS13235 940743af7fa13fc18a3bf5157202d0f6 2116 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 189 205 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site BWK49_RS13235 940743af7fa13fc18a3bf5157202d0f6 2116 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2065 2080 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site BWK49_RS13235 940743af7fa13fc18a3bf5157202d0f6 2116 SMART SM00829 1435 1747 4.2E-153 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 BWK49_RS13235 940743af7fa13fc18a3bf5157202d0f6 2116 SUPERFAMILY SSF50129 1430 1566 3.3E-31 T 06-07-2017 IPR011032 GroES-like BWK49_RS13235 940743af7fa13fc18a3bf5157202d0f6 2116 SUPERFAMILY SSF51735 1202 1409 2.6E-39 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS13235 940743af7fa13fc18a3bf5157202d0f6 2116 Pfam PF00698 Acyl transferase domain 554 870 9.1E-97 T 06-07-2017 IPR014043 Acyl transferase BWK49_RS13235 940743af7fa13fc18a3bf5157202d0f6 2116 SUPERFAMILY SSF52151 554 678 1.15E-60 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 BWK49_RS13235 940743af7fa13fc18a3bf5157202d0f6 2116 SUPERFAMILY SSF52151 743 839 1.15E-60 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 BWK49_RS13235 940743af7fa13fc18a3bf5157202d0f6 2116 Pfam PF00107 Zinc-binding dehydrogenase 1576 1671 1.9E-21 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 BWK49_RS13235 940743af7fa13fc18a3bf5157202d0f6 2116 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1771 1954 2.6E-42 T 06-07-2017 BWK49_RS13235 940743af7fa13fc18a3bf5157202d0f6 2116 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 408 520 2.3E-11 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS11115 7976bb2bacd5d336541fe6ba3d672905 404 Pfam PF04909 Amidohydrolase 103 402 3.0E-31 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 BWK49_RS11115 7976bb2bacd5d336541fe6ba3d672905 404 SUPERFAMILY SSF51556 14 43 2.97E-69 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS11115 7976bb2bacd5d336541fe6ba3d672905 404 SUPERFAMILY SSF51556 104 402 2.97E-69 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS11115 7976bb2bacd5d336541fe6ba3d672905 404 Gene3D G3DSA:3.20.20.140 91 403 5.0E-64 T 06-07-2017 BWK49_RS11115 7976bb2bacd5d336541fe6ba3d672905 404 Gene3D G3DSA:3.20.20.140 17 43 5.0E-64 T 06-07-2017 BWK49_RS12450 faf4eaece7e7ede36edd00ac64259253 419 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 262 376 6.2E-33 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal BWK49_RS12450 faf4eaece7e7ede36edd00ac64259253 419 Gene3D G3DSA:3.40.47.10 271 419 5.2E-53 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS12450 faf4eaece7e7ede36edd00ac64259253 419 SMART SM00825 Beta-ketoacyl synthase 13 410 9.9E-13 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain BWK49_RS12450 faf4eaece7e7ede36edd00ac64259253 419 SUPERFAMILY SSF53901 12 261 8.02E-49 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS12450 faf4eaece7e7ede36edd00ac64259253 419 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 12 254 4.3E-45 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal BWK49_RS12450 faf4eaece7e7ede36edd00ac64259253 419 SUPERFAMILY SSF53901 222 419 1.7E-64 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS12450 faf4eaece7e7ede36edd00ac64259253 419 Gene3D G3DSA:3.40.47.10 15 267 3.9E-48 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS25585 6d7665dae5330a40d2b662b7dd1a3351 172 SUPERFAMILY SSF109854 12 170 1.19E-29 T 06-07-2017 BWK49_RS25585 6d7665dae5330a40d2b662b7dd1a3351 172 Pfam PF04978 Protein of unknown function (DUF664) 14 171 3.1E-31 T 06-07-2017 IPR007061 Protein of unknown function DUF664 BWK49_RS25585 6d7665dae5330a40d2b662b7dd1a3351 172 Gene3D G3DSA:1.20.120.450 9 171 5.4E-72 T 06-07-2017 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase BWK49_RS07270 6598e4400a087c192d54b4bd3aa6cf12 544 Gene3D G3DSA:3.20.20.80 75 146 1.2E-4 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 BWK49_RS07270 6598e4400a087c192d54b4bd3aa6cf12 544 SUPERFAMILY SSF51445 91 260 1.41E-5 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily BWK49_RS05960 cebfecf8d59022d9089aafe38e8c8866 269 Gene3D G3DSA:3.40.50.720 4 258 2.8E-85 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS05960 cebfecf8d59022d9089aafe38e8c8866 269 SUPERFAMILY SSF51735 6 258 1.22E-80 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS05960 cebfecf8d59022d9089aafe38e8c8866 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 9.3E-44 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05960 cebfecf8d59022d9089aafe38e8c8866 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 9.3E-44 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05960 cebfecf8d59022d9089aafe38e8c8866 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 9.3E-44 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05960 cebfecf8d59022d9089aafe38e8c8866 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 9.3E-44 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05960 cebfecf8d59022d9089aafe38e8c8866 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 9.3E-44 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05960 cebfecf8d59022d9089aafe38e8c8866 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 220 240 9.3E-44 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05960 cebfecf8d59022d9089aafe38e8c8866 269 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 255 7.2E-65 T 06-07-2017 BWK49_RS05960 cebfecf8d59022d9089aafe38e8c8866 269 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 3.6E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05960 cebfecf8d59022d9089aafe38e8c8866 269 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 3.6E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05960 cebfecf8d59022d9089aafe38e8c8866 269 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 3.6E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS02960 b5b4d1564c5b819b3033386cda69acdf 314 Gene3D G3DSA:3.40.50.720 2 178 4.0E-52 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS02960 b5b4d1564c5b819b3033386cda69acdf 314 SUPERFAMILY SSF51735 2 311 6.5E-90 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS02960 b5b4d1564c5b819b3033386cda69acdf 314 Gene3D G3DSA:3.90.25.10 179 297 2.3E-31 T 06-07-2017 BWK49_RS02960 b5b4d1564c5b819b3033386cda69acdf 314 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 304 2.1E-56 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS07900 2d381a643234ac80a5daef702a460927 94 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 4 55 3.7E-16 T 06-07-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM BWK49_RS07900 2d381a643234ac80a5daef702a460927 94 SUPERFAMILY SSF143120 1 81 5.41E-21 T 06-07-2017 BWK49_RS07900 2d381a643234ac80a5daef702a460927 94 Gene3D G3DSA:3.40.1620.10 1 50 1.5E-13 T 06-07-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM BWK49_RS07900 2d381a643234ac80a5daef702a460927 94 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 72 3.9E-20 T 06-07-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM BWK49_RS09255 b4c3cdc12a78432fb6ad27c9724236a4 273 SUPERFAMILY SSF52096 13 273 2.26E-73 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS09255 b4c3cdc12a78432fb6ad27c9724236a4 273 Gene3D G3DSA:3.90.226.10 13 271 1.1E-67 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS09255 b4c3cdc12a78432fb6ad27c9724236a4 273 Pfam PF00378 Enoyl-CoA hydratase/isomerase 19 272 1.3E-48 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 BWK49_RS22000 d1cd5b0035deb9bede8d201afcb19748 235 TIGRFAM TIGR01961 NuoC_fam: NADH (or F420H2) dehydrogenase, subunit C 93 214 1.3E-44 T 06-07-2017 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS22000 d1cd5b0035deb9bede8d201afcb19748 235 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 94 215 2.9E-40 T 06-07-2017 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS22000 d1cd5b0035deb9bede8d201afcb19748 235 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 143 196 2.0E-22 T 06-07-2017 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS22000 d1cd5b0035deb9bede8d201afcb19748 235 SUPERFAMILY SSF143243 77 232 1.96E-48 T 06-07-2017 BWK49_RS22000 d1cd5b0035deb9bede8d201afcb19748 235 Hamap MF_01357 NAD(P)H-quinone oxidoreductase subunit J, chloroplastic [ndhJ]. 66 223 28.697 T 06-07-2017 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS05265 6b97af9f1dfa5b1769aba5e0d6bdebee 403 Pfam PF13542 Helix-turn-helix domain of transposase family ISL3 104 150 1.2E-10 T 06-07-2017 IPR032877 Transposase IS204/IS1001/IS1096/IS1165, helix-turn-helix domain BWK49_RS05265 6b97af9f1dfa5b1769aba5e0d6bdebee 403 Pfam PF01610 Transposase 170 403 4.6E-50 T 06-07-2017 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain BWK49_RS05265 6b97af9f1dfa5b1769aba5e0d6bdebee 403 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 48 88 3.1E-6 T 06-07-2017 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger BWK49_RS27840 88e99e1a3a8266cc836bf95a967ffa65 126 Gene3D G3DSA:3.10.450.50 6 118 1.1E-15 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS27840 88e99e1a3a8266cc836bf95a967ffa65 126 SUPERFAMILY SSF54427 8 117 1.28E-19 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS27840 88e99e1a3a8266cc836bf95a967ffa65 126 Pfam PF12680 SnoaL-like domain 10 113 4.7E-9 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain BWK49_RS27065 a16e71df079e3ac93c05cf0dde0732e3 950 Pfam PF03176 MMPL family 431 748 2.3E-32 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 BWK49_RS27065 a16e71df079e3ac93c05cf0dde0732e3 950 Pfam PF03176 MMPL family 47 402 3.3E-44 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 BWK49_RS27065 a16e71df079e3ac93c05cf0dde0732e3 950 Gene3D G3DSA:1.20.1640.10 531 749 1.7E-31 T 06-07-2017 BWK49_RS27065 a16e71df079e3ac93c05cf0dde0732e3 950 Gene3D G3DSA:1.20.1640.10 140 345 1.3E-25 T 06-07-2017 BWK49_RS27065 a16e71df079e3ac93c05cf0dde0732e3 950 SUPERFAMILY SSF82866 161 344 3.27E-26 T 06-07-2017 BWK49_RS27065 a16e71df079e3ac93c05cf0dde0732e3 950 SUPERFAMILY SSF82866 526 744 2.88E-31 T 06-07-2017 BWK49_RS26580 bf3a134c222d3b06440f3f7f39a6bf25 236 Gene3D G3DSA:1.10.357.10 44 192 9.2E-25 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS26580 bf3a134c222d3b06440f3f7f39a6bf25 236 SUPERFAMILY SSF46689 41 111 3.74E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS26580 bf3a134c222d3b06440f3f7f39a6bf25 236 Pfam PF00440 Bacterial regulatory proteins, tetR family 51 92 3.0E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS18120 a70bbded6e47528a52592fd200455449 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 235 256 4.6E-62 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 BWK49_RS18120 a70bbded6e47528a52592fd200455449 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 63 73 4.6E-62 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 BWK49_RS18120 a70bbded6e47528a52592fd200455449 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 145 169 4.6E-62 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 BWK49_RS18120 a70bbded6e47528a52592fd200455449 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 270 288 4.6E-62 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 BWK49_RS18120 a70bbded6e47528a52592fd200455449 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 42 57 4.6E-62 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 BWK49_RS18120 a70bbded6e47528a52592fd200455449 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 9 31 4.6E-62 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 BWK49_RS18120 a70bbded6e47528a52592fd200455449 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 108 116 4.6E-62 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 BWK49_RS18120 a70bbded6e47528a52592fd200455449 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 130 142 4.6E-62 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 BWK49_RS18120 a70bbded6e47528a52592fd200455449 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 197 213 4.6E-62 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 BWK49_RS18120 a70bbded6e47528a52592fd200455449 316 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 296 5.4E-43 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS18120 a70bbded6e47528a52592fd200455449 316 Gene3D G3DSA:3.50.50.60 112 298 3.2E-33 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS18120 a70bbded6e47528a52592fd200455449 316 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 10 29 2.2E-36 T 06-07-2017 BWK49_RS18120 a70bbded6e47528a52592fd200455449 316 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 260 282 2.2E-36 T 06-07-2017 BWK49_RS18120 a70bbded6e47528a52592fd200455449 316 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 233 249 2.2E-36 T 06-07-2017 BWK49_RS18120 a70bbded6e47528a52592fd200455449 316 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 149 167 2.2E-36 T 06-07-2017 BWK49_RS18120 a70bbded6e47528a52592fd200455449 316 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 107 125 2.2E-36 T 06-07-2017 BWK49_RS18120 a70bbded6e47528a52592fd200455449 316 Gene3D G3DSA:3.50.50.60 7 111 7.1E-28 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS18120 a70bbded6e47528a52592fd200455449 316 SUPERFAMILY SSF51905 4 303 5.46E-46 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS11740 fad743fe86d41a49f5139b23ac21abe1 283 Gene3D G3DSA:3.40.50.1820 20 282 1.7E-42 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS11740 fad743fe86d41a49f5139b23ac21abe1 283 SUPERFAMILY SSF53474 22 282 6.08E-41 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS11740 fad743fe86d41a49f5139b23ac21abe1 283 Pfam PF12697 Alpha/beta hydrolase family 25 275 8.5E-15 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS11740 fad743fe86d41a49f5139b23ac21abe1 283 PRINTS PR00412 Epoxide hydrolase signature 258 280 4.5E-16 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS11740 fad743fe86d41a49f5139b23ac21abe1 283 PRINTS PR00412 Epoxide hydrolase signature 91 104 4.5E-16 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS11740 fad743fe86d41a49f5139b23ac21abe1 283 PRINTS PR00412 Epoxide hydrolase signature 48 63 4.5E-16 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS11740 fad743fe86d41a49f5139b23ac21abe1 283 PRINTS PR00412 Epoxide hydrolase signature 223 239 4.5E-16 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS11740 fad743fe86d41a49f5139b23ac21abe1 283 PRINTS PR00412 Epoxide hydrolase signature 28 46 4.5E-16 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS19395 782b1391c70f742bf73ec4d4cc46d8ce 154 Hamap MF_00116 Deoxyuridine 5'-triphosphate nucleotidohydrolase [dut]. 3 150 30.803 T 06-07-2017 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7206|Reactome: R-HSA-500753 BWK49_RS19395 782b1391c70f742bf73ec4d4cc46d8ce 154 Pfam PF00692 dUTPase 15 149 1.1E-28 T 06-07-2017 IPR008180 Deoxyuridine triphosphate nucleotidohydrolase/Deoxycytidine triphosphate deaminase GO:0016787|GO:0046080 BWK49_RS19395 782b1391c70f742bf73ec4d4cc46d8ce 154 TIGRFAM TIGR00576 dut: dUTP diphosphatase 5 149 8.7E-50 T 06-07-2017 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7206|Reactome: R-HSA-500753 BWK49_RS19395 782b1391c70f742bf73ec4d4cc46d8ce 154 SUPERFAMILY SSF51283 4 149 2.62E-44 T 06-07-2017 IPR029054 dUTPase-like BWK49_RS19395 782b1391c70f742bf73ec4d4cc46d8ce 154 Gene3D G3DSA:2.70.40.10 3 149 4.7E-55 T 06-07-2017 IPR029054 dUTPase-like BWK49_RS19375 07c03af17f0f9731ea0c58c2ffcf96e5 235 Pfam PF11361 Protein of unknown function (DUF3159) 37 220 2.2E-64 T 06-07-2017 IPR016566 Uncharacterised conserved protein UCP010219 BWK49_RS19375 07c03af17f0f9731ea0c58c2ffcf96e5 235 PIRSF PIRSF010219 12 232 2.4E-82 T 06-07-2017 IPR016566 Uncharacterised conserved protein UCP010219 BWK49_RS26420 f8bce2016d2aa07f567f65087e366a4c 474 Pfam PF08817 WXG100 protein secretion system (Wss), protein YukD 3 92 1.4E-21 T 06-07-2017 IPR024962 YukD-like BWK49_RS26420 f8bce2016d2aa07f567f65087e366a4c 474 TIGRFAM TIGR03920 T7SS_EccD: type VII secretion integral membrane protein EccD 6 473 4.1E-109 T 06-07-2017 IPR006707 Type VII secretion system membrane protein EccD BWK49_RS26420 f8bce2016d2aa07f567f65087e366a4c 474 PIRSF PIRSF017804 1 474 8.1E-96 T 06-07-2017 IPR006707 Type VII secretion system membrane protein EccD BWK49_RS08875 28b3f7eb13774e7f4b34b6810a02c2cc 550 Pfam PF00750 tRNA synthetases class I (R) 245 390 9.2E-11 T 06-07-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 BWK49_RS08875 28b3f7eb13774e7f4b34b6810a02c2cc 550 Pfam PF05746 DALR anticodon binding domain 429 550 3.1E-39 T 06-07-2017 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 BWK49_RS08875 28b3f7eb13774e7f4b34b6810a02c2cc 550 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 9 550 5.1E-122 T 06-07-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 BWK49_RS08875 28b3f7eb13774e7f4b34b6810a02c2cc 550 SUPERFAMILY SSF47323 423 550 5.75E-37 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 BWK49_RS08875 28b3f7eb13774e7f4b34b6810a02c2cc 550 PRINTS PR01038 Arginyl-tRNA synthetase signature 137 153 1.7E-23 T 06-07-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 BWK49_RS08875 28b3f7eb13774e7f4b34b6810a02c2cc 550 PRINTS PR01038 Arginyl-tRNA synthetase signature 161 174 1.7E-23 T 06-07-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 BWK49_RS08875 28b3f7eb13774e7f4b34b6810a02c2cc 550 PRINTS PR01038 Arginyl-tRNA synthetase signature 298 319 1.7E-23 T 06-07-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 BWK49_RS08875 28b3f7eb13774e7f4b34b6810a02c2cc 550 PRINTS PR01038 Arginyl-tRNA synthetase signature 122 137 1.7E-23 T 06-07-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 BWK49_RS08875 28b3f7eb13774e7f4b34b6810a02c2cc 550 SMART SM00836 429 550 1.8E-54 T 06-07-2017 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 BWK49_RS08875 28b3f7eb13774e7f4b34b6810a02c2cc 550 Gene3D G3DSA:3.30.1360.70 3 111 1.3E-29 T 06-07-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 BWK49_RS08875 28b3f7eb13774e7f4b34b6810a02c2cc 550 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 132 141 - T 06-07-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 BWK49_RS08875 28b3f7eb13774e7f4b34b6810a02c2cc 550 Gene3D G3DSA:3.40.50.620 117 434 8.5E-91 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold BWK49_RS08875 28b3f7eb13774e7f4b34b6810a02c2cc 550 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 24 93 4.3E-22 T 06-07-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 BWK49_RS08875 28b3f7eb13774e7f4b34b6810a02c2cc 550 SMART SM01016 4 93 3.8E-34 T 06-07-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 BWK49_RS08875 28b3f7eb13774e7f4b34b6810a02c2cc 550 Hamap MF_00123 Arginine--tRNA ligase [argS]. 8 550 25.35 T 06-07-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 BWK49_RS08875 28b3f7eb13774e7f4b34b6810a02c2cc 550 SUPERFAMILY SSF52374 118 438 5.63E-79 T 06-07-2017 BWK49_RS08875 28b3f7eb13774e7f4b34b6810a02c2cc 550 Gene3D G3DSA:1.10.730.10 435 550 2.5E-44 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 BWK49_RS08875 28b3f7eb13774e7f4b34b6810a02c2cc 550 SUPERFAMILY SSF55190 5 113 6.41E-23 T 06-07-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 BWK49_RS04145 1a61c42f88fac5ab6c37ac8fe78b3470 258 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 6 258 5.3E-113 T 06-07-2017 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 BWK49_RS04145 1a61c42f88fac5ab6c37ac8fe78b3470 258 Pfam PF00005 ABC transporter 22 176 1.4E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 BWK49_RS04145 1a61c42f88fac5ab6c37ac8fe78b3470 258 SUPERFAMILY SSF52540 5 245 2.06E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS04145 1a61c42f88fac5ab6c37ac8fe78b3470 258 Gene3D G3DSA:3.40.50.300 4 250 8.3E-64 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS04145 1a61c42f88fac5ab6c37ac8fe78b3470 258 SMART SM00382 29 229 5.2E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS04145 1a61c42f88fac5ab6c37ac8fe78b3470 258 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 BWK49_RS27925 c2872738ed45b1a216125d09d6dd6631 203 Pfam PF13649 Methyltransferase domain 32 122 6.7E-17 T 06-07-2017 BWK49_RS27925 c2872738ed45b1a216125d09d6dd6631 203 Gene3D G3DSA:3.40.50.150 15 137 2.4E-26 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS27925 c2872738ed45b1a216125d09d6dd6631 203 SUPERFAMILY SSF53335 14 136 1.14E-26 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS11915 9a9092659e3ed740643b335d901c427e 468 Gene3D G3DSA:3.40.605.10 3 252 5.1E-93 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 BWK49_RS11915 9a9092659e3ed740643b335d901c427e 468 Gene3D G3DSA:3.40.309.10 253 437 2.2E-68 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 BWK49_RS11915 9a9092659e3ed740643b335d901c427e 468 SUPERFAMILY SSF53720 3 467 1.96E-160 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 BWK49_RS11915 9a9092659e3ed740643b335d901c427e 468 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 240 247 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 BWK49_RS11915 9a9092659e3ed740643b335d901c427e 468 Pfam PF00171 Aldehyde dehydrogenase family 3 464 2.2E-179 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 BWK49_RS20920 ae942ab6d71e655c10f3055b71c1419b 528 Gene3D G3DSA:3.40.50.720 109 283 7.5E-70 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS20920 ae942ab6d71e655c10f3055b71c1419b 528 Gene3D G3DSA:3.30.70.260 447 521 7.9E-12 T 06-07-2017 BWK49_RS20920 ae942ab6d71e655c10f3055b71c1419b 528 Gene3D G3DSA:3.40.50.720 5 108 5.8E-39 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS20920 ae942ab6d71e655c10f3055b71c1419b 528 SUPERFAMILY SSF51735 100 281 4.52E-60 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS20920 ae942ab6d71e655c10f3055b71c1419b 528 SUPERFAMILY SSF52283 4 134 7.56E-39 T 06-07-2017 BWK49_RS20920 ae942ab6d71e655c10f3055b71c1419b 528 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 6 313 3.4E-38 T 06-07-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 BWK49_RS20920 ae942ab6d71e655c10f3055b71c1419b 528 TIGRFAM TIGR01327 PGDH: phosphoglycerate dehydrogenase 6 527 5.3E-201 T 06-07-2017 IPR006236 D-3-phosphoglycerate dehydrogenase GO:0004617|GO:0006564 KEGG: 00260+1.1.1.95|KEGG: 00680+1.1.1.95|Reactome: R-HSA-977347 BWK49_RS20920 ae942ab6d71e655c10f3055b71c1419b 528 SUPERFAMILY SSF55021 454 522 4.58E-12 T 06-07-2017 BWK49_RS20920 ae942ab6d71e655c10f3055b71c1419b 528 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 144 171 - T 06-07-2017 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 BWK49_RS20920 ae942ab6d71e655c10f3055b71c1419b 528 Pfam PF01842 ACT domain 457 515 7.4E-7 T 06-07-2017 IPR002912 ACT domain GO:0008152|GO:0016597 BWK49_RS20920 ae942ab6d71e655c10f3055b71c1419b 528 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 221 237 - T 06-07-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site BWK49_RS20920 ae942ab6d71e655c10f3055b71c1419b 528 Gene3D G3DSA:3.30.1330.90 319 446 1.2E-39 T 06-07-2017 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 BWK49_RS20920 ae942ab6d71e655c10f3055b71c1419b 528 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 107 281 7.9E-63 T 06-07-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 BWK49_RS20920 ae942ab6d71e655c10f3055b71c1419b 528 SUPERFAMILY SSF143548 320 449 1.05E-32 T 06-07-2017 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 BWK49_RS20920 ae942ab6d71e655c10f3055b71c1419b 528 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 192 214 - T 06-07-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site BWK49_RS16020 4144bdb22ec6b6fcc1235c9a01bc27a7 170 SUPERFAMILY SSF55729 58 148 7.75E-11 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase BWK49_RS16020 4144bdb22ec6b6fcc1235c9a01bc27a7 170 Pfam PF13508 Acetyltransferase (GNAT) domain 64 145 7.9E-8 T 06-07-2017 IPR000182 GNAT domain GO:0008080 BWK49_RS16020 4144bdb22ec6b6fcc1235c9a01bc27a7 170 Gene3D G3DSA:3.40.630.30 40 149 3.4E-12 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase BWK49_RS16230 4f930e44623594ddf2549acea5d601c6 354 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 222 5.3E-29 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 BWK49_RS16230 4f930e44623594ddf2549acea5d601c6 354 SUPERFAMILY SSF51735 295 332 2.11E-55 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS16230 4f930e44623594ddf2549acea5d601c6 354 SUPERFAMILY SSF51735 1 267 2.11E-55 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS16230 4f930e44623594ddf2549acea5d601c6 354 Gene3D G3DSA:3.40.50.720 1 290 1.6E-48 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS01270 c3bae67248e214e95c291eeaa86f4224 305 Pfam PF13641 Glycosyltransferase like family 2 6 250 3.1E-10 T 06-07-2017 BWK49_RS01270 c3bae67248e214e95c291eeaa86f4224 305 SUPERFAMILY SSF53448 4 277 2.91E-32 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases BWK49_RS01270 c3bae67248e214e95c291eeaa86f4224 305 Gene3D G3DSA:3.90.550.10 8 222 5.3E-15 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases BWK49_RS14395 46fa73bf77b87f5a10f20434f75135b1 213 Pfam PF02627 Carboxymuconolactone decarboxylase family 68 132 6.1E-7 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 BWK49_RS14395 46fa73bf77b87f5a10f20434f75135b1 213 Gene3D G3DSA:1.20.1290.10 43 186 9.6E-30 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 BWK49_RS14395 46fa73bf77b87f5a10f20434f75135b1 213 SUPERFAMILY SSF69118 1 186 2.36E-34 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 BWK49_RS14010 ac21b62172e368cda2e721f20bc7a741 197 Pfam PF13649 Methyltransferase domain 39 133 1.9E-20 T 06-07-2017 BWK49_RS14010 ac21b62172e368cda2e721f20bc7a741 197 Gene3D G3DSA:3.40.50.150 29 177 4.8E-28 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS14010 ac21b62172e368cda2e721f20bc7a741 197 SUPERFAMILY SSF53335 16 145 1.14E-31 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS15840 1449ca57dc560d2953cef075e948c77f 288 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 184 201 6.5E-18 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15840 1449ca57dc560d2953cef075e948c77f 288 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 6.5E-18 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15840 1449ca57dc560d2953cef075e948c77f 288 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 6.5E-18 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15840 1449ca57dc560d2953cef075e948c77f 288 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 6.5E-18 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15840 1449ca57dc560d2953cef075e948c77f 288 SUPERFAMILY SSF51735 7 252 7.67E-59 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS15840 1449ca57dc560d2953cef075e948c77f 288 Pfam PF00106 short chain dehydrogenase 11 202 1.4E-43 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15840 1449ca57dc560d2953cef075e948c77f 288 Gene3D G3DSA:3.40.50.720 9 248 1.4E-60 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS15840 1449ca57dc560d2953cef075e948c77f 288 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 1.8E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15840 1449ca57dc560d2953cef075e948c77f 288 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 1.8E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15840 1449ca57dc560d2953cef075e948c77f 288 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 1.8E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS28215 2ab858404fa183a0aa43784d47369303 442 Pfam PF00355 Rieske [2Fe-2S] domain 48 130 4.2E-16 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS28215 2ab858404fa183a0aa43784d47369303 442 Gene3D G3DSA:2.102.10.10 48 151 1.3E-23 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS28215 2ab858404fa183a0aa43784d47369303 442 SUPERFAMILY SSF55961 274 430 7.06E-33 T 06-07-2017 BWK49_RS28215 2ab858404fa183a0aa43784d47369303 442 SUPERFAMILY SSF55961 161 247 7.06E-33 T 06-07-2017 BWK49_RS28215 2ab858404fa183a0aa43784d47369303 442 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 182 428 5.9E-28 T 06-07-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 BWK49_RS28215 2ab858404fa183a0aa43784d47369303 442 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 83 103 1.1E-21 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS28215 2ab858404fa183a0aa43784d47369303 442 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 62 77 1.1E-21 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS28215 2ab858404fa183a0aa43784d47369303 442 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 32 57 1.1E-21 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS28215 2ab858404fa183a0aa43784d47369303 442 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 104 124 1.1E-21 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS28215 2ab858404fa183a0aa43784d47369303 442 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 145 171 1.1E-21 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS28215 2ab858404fa183a0aa43784d47369303 442 SUPERFAMILY SSF50022 18 159 1.83E-42 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS28215 2ab858404fa183a0aa43784d47369303 442 Gene3D G3DSA:3.90.380.10 152 416 3.1E-22 T 06-07-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 BWK49_RS20295 5e0f737deaf082c33518652ddb5329bf 171 Pfam PF01782 RimM N-terminal domain 5 88 6.8E-22 T 06-07-2017 IPR002676 RimM protein GO:0006364 BWK49_RS20295 5e0f737deaf082c33518652ddb5329bf 171 SUPERFAMILY SSF50447 3 92 4.94E-19 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain BWK49_RS20295 5e0f737deaf082c33518652ddb5329bf 171 Pfam PF05239 PRC-barrel domain 97 169 3.0E-10 T 06-07-2017 IPR027275 PRC-barrel domain BWK49_RS20295 5e0f737deaf082c33518652ddb5329bf 171 Gene3D G3DSA:2.40.30.60 3 92 5.2E-24 T 06-07-2017 IPR002676 RimM protein GO:0006364 BWK49_RS20295 5e0f737deaf082c33518652ddb5329bf 171 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 3 168 4.5E-43 T 06-07-2017 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 BWK49_RS20295 5e0f737deaf082c33518652ddb5329bf 171 SUPERFAMILY SSF50346 99 168 3.92E-16 T 06-07-2017 IPR011033 PRC-barrel-like BWK49_RS20295 5e0f737deaf082c33518652ddb5329bf 171 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 2 168 22.143 T 06-07-2017 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 BWK49_RS20295 5e0f737deaf082c33518652ddb5329bf 171 Gene3D G3DSA:2.30.30.240 99 168 2.1E-18 T 06-07-2017 BWK49_RS08010 e733c5caa0c5a9cf5b6cd927b9336063 173 Pfam PF07681 DoxX 11 96 2.4E-20 T 06-07-2017 IPR032808 DoxX family BWK49_RS02265 0800e4b4aa1adb68505a01df4039e729 219 Pfam PF07729 FCD domain 86 202 1.9E-22 T 06-07-2017 IPR011711 GntR, C-terminal BWK49_RS02265 0800e4b4aa1adb68505a01df4039e729 219 SMART SM00895 85 204 6.7E-17 T 06-07-2017 IPR011711 GntR, C-terminal BWK49_RS02265 0800e4b4aa1adb68505a01df4039e729 219 Gene3D G3DSA:1.20.120.530 78 216 9.0E-26 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal BWK49_RS02265 0800e4b4aa1adb68505a01df4039e729 219 SMART SM00345 17 75 2.5E-14 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 BWK49_RS02265 0800e4b4aa1adb68505a01df4039e729 219 Gene3D G3DSA:1.10.10.10 10 75 3.8E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS02265 0800e4b4aa1adb68505a01df4039e729 219 SUPERFAMILY SSF48008 81 212 9.42E-21 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal BWK49_RS02265 0800e4b4aa1adb68505a01df4039e729 219 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 75 1.5E-15 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 BWK49_RS02265 0800e4b4aa1adb68505a01df4039e729 219 SUPERFAMILY SSF46785 12 79 1.15E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS12130 2c347ae40d645cf138b8746d4a1ea739 499 Gene3D G3DSA:3.40.50.270 359 481 2.2E-37 T 06-07-2017 BWK49_RS12130 2c347ae40d645cf138b8746d4a1ea739 499 Pfam PF01758 Sodium Bile acid symporter family 54 250 3.0E-63 T 06-07-2017 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 BWK49_RS12130 2c347ae40d645cf138b8746d4a1ea739 499 SMART SM00226 359 483 8.1E-41 T 06-07-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily BWK49_RS12130 2c347ae40d645cf138b8746d4a1ea739 499 SUPERFAMILY SSF52788 359 481 4.97E-34 T 06-07-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily BWK49_RS12130 2c347ae40d645cf138b8746d4a1ea739 499 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 361 480 2.9E-20 T 06-07-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily BWK49_RS12130 2c347ae40d645cf138b8746d4a1ea739 499 TIGRFAM TIGR00832 acr3: arsenical-resistance protein 9 337 9.2E-134 T 06-07-2017 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 BWK49_RS25330 b3809810d12c96b8de93912a2d8ebead 295 Gene3D G3DSA:3.40.50.720 5 165 6.5E-41 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS25330 b3809810d12c96b8de93912a2d8ebead 295 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 8 290 2.7E-86 T 06-07-2017 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 BWK49_RS25330 b3809810d12c96b8de93912a2d8ebead 295 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 7 106 1.8E-22 T 06-07-2017 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal BWK49_RS25330 b3809810d12c96b8de93912a2d8ebead 295 SUPERFAMILY SSF48179 168 290 5.78E-29 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 BWK49_RS25330 b3809810d12c96b8de93912a2d8ebead 295 Gene3D G3DSA:1.10.3730.10 168 290 1.9E-38 T 06-07-2017 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 BWK49_RS25330 b3809810d12c96b8de93912a2d8ebead 295 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 6 290 27.406 T 06-07-2017 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 BWK49_RS25330 b3809810d12c96b8de93912a2d8ebead 295 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 169 290 1.2E-38 T 06-07-2017 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 BWK49_RS25330 b3809810d12c96b8de93912a2d8ebead 295 SUPERFAMILY SSF51735 7 165 1.08E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS25330 b3809810d12c96b8de93912a2d8ebead 295 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 246 268 - T 06-07-2017 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 BWK49_RS01050 b6d0459113e52eeb238d552a57770418 116 Pfam PF06262 Zinicin-like metallopeptidase 29 115 8.3E-34 T 06-07-2017 IPR010428 Zinicin-like metallopeptidase BWK49_RS01050 b6d0459113e52eeb238d552a57770418 116 SUPERFAMILY SSF55486 3 115 2.72E-37 T 06-07-2017 BWK49_RS27400 ab4007f7d3573d051c6a400250049551 446 Gene3D G3DSA:3.30.465.10 93 212 1.9E-31 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 BWK49_RS27400 ab4007f7d3573d051c6a400250049551 446 Gene3D G3DSA:1.10.45.10 405 440 8.1E-7 T 06-07-2017 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 BWK49_RS27400 ab4007f7d3573d051c6a400250049551 446 Pfam PF01565 FAD binding domain 37 173 7.5E-34 T 06-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 BWK49_RS27400 ab4007f7d3573d051c6a400250049551 446 SUPERFAMILY SSF55103 215 445 2.94E-42 T 06-07-2017 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 BWK49_RS27400 ab4007f7d3573d051c6a400250049551 446 Gene3D G3DSA:3.30.43.10 2 89 4.0E-20 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 BWK49_RS27400 ab4007f7d3573d051c6a400250049551 446 SUPERFAMILY SSF56176 2 212 8.72E-62 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 BWK49_RS27400 ab4007f7d3573d051c6a400250049551 446 Pfam PF02913 FAD linked oxidases, C-terminal domain 211 441 1.2E-51 T 06-07-2017 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 BWK49_RS16435 8fe628f4290ed3906a90c2dc45211a1b 992 Pfam PF00698 Acyl transferase domain 61 378 6.9E-55 T 06-07-2017 IPR014043 Acyl transferase BWK49_RS16435 8fe628f4290ed3906a90c2dc45211a1b 992 SMART SM00823 Phosphopantetheine attachment site 917 989 0.0018 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS16435 8fe628f4290ed3906a90c2dc45211a1b 992 ProSitePatterns PS00012 Phosphopantetheine attachment site. 944 959 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site BWK49_RS16435 8fe628f4290ed3906a90c2dc45211a1b 992 SUPERFAMILY SSF47336 916 985 1.31E-10 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS16435 8fe628f4290ed3906a90c2dc45211a1b 992 SUPERFAMILY SSF51735 655 858 2.41E-31 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS16435 8fe628f4290ed3906a90c2dc45211a1b 992 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 655 833 1.8E-11 T 06-07-2017 BWK49_RS16435 8fe628f4290ed3906a90c2dc45211a1b 992 SUPERFAMILY SSF51735 455 641 3.62E-15 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS16435 8fe628f4290ed3906a90c2dc45211a1b 992 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 62 365 1.4E-54 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain BWK49_RS16435 8fe628f4290ed3906a90c2dc45211a1b 992 Gene3D G3DSA:1.10.1200.10 918 980 2.1E-9 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS16435 8fe628f4290ed3906a90c2dc45211a1b 992 Gene3D G3DSA:3.40.50.720 656 832 3.3E-25 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS16435 8fe628f4290ed3906a90c2dc45211a1b 992 SUPERFAMILY SSF52151 58 186 9.94E-48 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 BWK49_RS16435 8fe628f4290ed3906a90c2dc45211a1b 992 SUPERFAMILY SSF52151 251 346 9.94E-48 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 BWK49_RS16435 8fe628f4290ed3906a90c2dc45211a1b 992 SUPERFAMILY SSF55048 186 249 6.28E-8 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 BWK49_RS16435 8fe628f4290ed3906a90c2dc45211a1b 992 Gene3D G3DSA:3.40.366.10 249 364 1.0E-51 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 BWK49_RS16435 8fe628f4290ed3906a90c2dc45211a1b 992 Gene3D G3DSA:3.40.366.10 59 180 1.0E-51 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 BWK49_RS16435 8fe628f4290ed3906a90c2dc45211a1b 992 Pfam PF00550 Phosphopantetheine attachment site 918 982 5.2E-10 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS16435 8fe628f4290ed3906a90c2dc45211a1b 992 Pfam PF08659 KR domain 657 831 2.1E-36 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS07980 378df18f77c618d53338bd876abc7dad 287 Gene3D G3DSA:3.40.50.1820 12 286 4.8E-62 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS07980 378df18f77c618d53338bd876abc7dad 287 SUPERFAMILY SSF53474 9 285 6.18E-51 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS07980 378df18f77c618d53338bd876abc7dad 287 PRINTS PR00412 Epoxide hydrolase signature 261 283 5.6E-7 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS07980 378df18f77c618d53338bd876abc7dad 287 PRINTS PR00412 Epoxide hydrolase signature 42 60 5.6E-7 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS07980 378df18f77c618d53338bd876abc7dad 287 PRINTS PR00412 Epoxide hydrolase signature 62 77 5.6E-7 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS07980 378df18f77c618d53338bd876abc7dad 287 PRINTS PR00412 Epoxide hydrolase signature 228 244 5.6E-7 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS07980 378df18f77c618d53338bd876abc7dad 287 Pfam PF00561 alpha/beta hydrolase fold 36 269 1.8E-21 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS09810 c486374e3b3419b883b040e2c9c090cc 81 SUPERFAMILY SSF143120 3 78 4.71E-18 T 06-07-2017 BWK49_RS09810 c486374e3b3419b883b040e2c9c090cc 81 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 2 53 6.3E-15 T 06-07-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM BWK49_RS09810 c486374e3b3419b883b040e2c9c090cc 81 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 2 69 4.1E-17 T 06-07-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM BWK49_RS14735 07cb349d986800ea90764261c77bde52 330 Gene3D G3DSA:3.40.50.1820 43 324 5.4E-127 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS14735 07cb349d986800ea90764261c77bde52 330 SUPERFAMILY SSF53474 41 324 3.28E-37 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS14735 07cb349d986800ea90764261c77bde52 330 Pfam PF00756 Putative esterase 55 318 1.3E-75 T 06-07-2017 IPR000801 Putative esterase Reactome: R-HSA-156590 BWK49_RS05250 2163b435aa5bfa48c8683543b98f4564 380 Gene3D G3DSA:1.10.540.10 5 121 1.4E-33 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS05250 2163b435aa5bfa48c8683543b98f4564 380 SUPERFAMILY SSF56645 5 244 5.76E-81 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS05250 2163b435aa5bfa48c8683543b98f4564 380 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 339 358 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 BWK49_RS05250 2163b435aa5bfa48c8683543b98f4564 380 Gene3D G3DSA:2.40.110.10 123 219 7.2E-39 T 06-07-2017 BWK49_RS05250 2163b435aa5bfa48c8683543b98f4564 380 Gene3D G3DSA:1.20.140.10 220 380 2.5E-52 T 06-07-2017 BWK49_RS05250 2163b435aa5bfa48c8683543b98f4564 380 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 120 5.4E-30 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS05250 2163b435aa5bfa48c8683543b98f4564 380 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 232 380 7.0E-40 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS05250 2163b435aa5bfa48c8683543b98f4564 380 SUPERFAMILY SSF47203 231 380 1.45E-47 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS05250 2163b435aa5bfa48c8683543b98f4564 380 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 124 219 2.9E-26 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 BWK49_RS09035 9cdd41843a7e43c47052811950514597 163 SUPERFAMILY SSF53155 3 79 8.63E-20 T 06-07-2017 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 BWK49_RS09035 9cdd41843a7e43c47052811950514597 163 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 1 65 3.6E-9 T 06-07-2017 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 BWK49_RS09035 9cdd41843a7e43c47052811950514597 163 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 124 130 - T 06-07-2017 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 BWK49_RS09035 9cdd41843a7e43c47052811950514597 163 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 75 153 4.2E-36 T 06-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 BWK49_RS09035 9cdd41843a7e43c47052811950514597 163 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 2 156 40.898 T 06-07-2017 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 BWK49_RS09035 9cdd41843a7e43c47052811950514597 163 Gene3D G3DSA:1.10.10.10 73 155 2.4E-36 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS09035 9cdd41843a7e43c47052811950514597 163 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 75 154 1.6E-34 T 06-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 BWK49_RS09035 9cdd41843a7e43c47052811950514597 163 SUPERFAMILY SSF46767 73 154 1.96E-33 T 06-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 BWK49_RS07180 e75b8cea22ceb1f6368c2805f4f926b1 597 SUPERFAMILY SSF53474 4 356 7.79E-39 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS07180 e75b8cea22ceb1f6368c2805f4f926b1 597 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 349 566 7.3E-29 T 06-07-2017 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 BWK49_RS07180 e75b8cea22ceb1f6368c2805f4f926b1 597 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 9 590 1.3E-72 T 06-07-2017 IPR005674 CocE/Serine esterase GO:0016787 BWK49_RS07180 e75b8cea22ceb1f6368c2805f4f926b1 597 Gene3D G3DSA:3.40.50.1820 231 353 2.8E-64 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS07180 e75b8cea22ceb1f6368c2805f4f926b1 597 Gene3D G3DSA:3.40.50.1820 3 157 2.8E-64 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS07180 e75b8cea22ceb1f6368c2805f4f926b1 597 SMART SM00939 321 587 2.6E-36 T 06-07-2017 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 BWK49_RS07180 e75b8cea22ceb1f6368c2805f4f926b1 597 Gene3D G3DSA:2.60.120.260 354 593 3.0E-46 T 06-07-2017 IPR008979 Galactose-binding domain-like BWK49_RS07180 e75b8cea22ceb1f6368c2805f4f926b1 597 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 13 308 2.3E-43 T 06-07-2017 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 BWK49_RS07180 e75b8cea22ceb1f6368c2805f4f926b1 597 SUPERFAMILY SSF49785 349 591 2.34E-31 T 06-07-2017 IPR008979 Galactose-binding domain-like BWK49_RS22445 3913f4dbb4a4694b6310d38924080275 83 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 8 41 7.4E-9 T 06-07-2017 BWK49_RS22445 3913f4dbb4a4694b6310d38924080275 83 SUPERFAMILY SSF51735 8 42 7.58E-11 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS22445 3913f4dbb4a4694b6310d38924080275 83 Gene3D G3DSA:3.40.50.720 8 44 5.7E-12 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS19230 d7039621b89c93e03af2110093983551 306 Gene3D G3DSA:3.30.70.1350 227 296 8.9E-6 T 06-07-2017 IPR027470 Cation efflux protein, cytoplasmic domain BWK49_RS19230 d7039621b89c93e03af2110093983551 306 SUPERFAMILY SSF161111 26 227 2.35E-49 T 06-07-2017 BWK49_RS19230 d7039621b89c93e03af2110093983551 306 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 30 290 2.8E-57 T 06-07-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 BWK49_RS19230 d7039621b89c93e03af2110093983551 306 Pfam PF01545 Cation efflux family 36 225 1.9E-38 T 06-07-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 BWK49_RS19230 d7039621b89c93e03af2110093983551 306 Gene3D G3DSA:1.20.1510.10 31 226 1.3E-37 T 06-07-2017 IPR027469 Cation efflux protein transmembrane domain BWK49_RS10255 944750d7843e09586a934c0b6761ec2f 555 SUPERFAMILY SSF56014 162 320 9.03E-44 T 06-07-2017 BWK49_RS10255 944750d7843e09586a934c0b6761ec2f 555 PRINTS PR00397 Sirohaem Fe-binding site signature 461 479 2.6E-9 T 06-07-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 BWK49_RS10255 944750d7843e09586a934c0b6761ec2f 555 PRINTS PR00397 Sirohaem Fe-binding site signature 412 430 2.6E-9 T 06-07-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 BWK49_RS10255 944750d7843e09586a934c0b6761ec2f 555 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 338 400 1.7E-13 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 BWK49_RS10255 944750d7843e09586a934c0b6761ec2f 555 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 92 152 1.8E-13 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 BWK49_RS10255 944750d7843e09586a934c0b6761ec2f 555 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 412 549 4.8E-8 T 06-07-2017 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 BWK49_RS10255 944750d7843e09586a934c0b6761ec2f 555 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 162 313 9.5E-36 T 06-07-2017 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 BWK49_RS10255 944750d7843e09586a934c0b6761ec2f 555 Gene3D G3DSA:3.90.480.10 90 159 2.1E-43 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 BWK49_RS10255 944750d7843e09586a934c0b6761ec2f 555 Gene3D G3DSA:3.90.480.10 328 405 2.1E-43 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 BWK49_RS10255 944750d7843e09586a934c0b6761ec2f 555 Gene3D G3DSA:3.30.413.10 162 311 5.2E-40 T 06-07-2017 BWK49_RS10255 944750d7843e09586a934c0b6761ec2f 555 SUPERFAMILY SSF55124 292 423 4.74E-19 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 BWK49_RS10255 944750d7843e09586a934c0b6761ec2f 555 SUPERFAMILY SSF56014 408 555 5.1E-36 T 06-07-2017 BWK49_RS10255 944750d7843e09586a934c0b6761ec2f 555 Gene3D G3DSA:3.30.413.10 410 555 2.3E-33 T 06-07-2017 BWK49_RS10255 944750d7843e09586a934c0b6761ec2f 555 SUPERFAMILY SSF55124 11 161 3.11E-39 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 BWK49_RS10255 944750d7843e09586a934c0b6761ec2f 555 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 461 477 - T 06-07-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 BWK49_RS15865 a4833b760eb555b05dca5e361bd3ef3a 262 Gene3D G3DSA:3.40.50.720 1 195 3.3E-37 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS15865 a4833b760eb555b05dca5e361bd3ef3a 262 SUPERFAMILY SSF51735 1 197 1.44E-37 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS15865 a4833b760eb555b05dca5e361bd3ef3a 262 Pfam PF00106 short chain dehydrogenase 1 181 7.1E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15865 a4833b760eb555b05dca5e361bd3ef3a 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 116 132 1.4E-15 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15865 a4833b760eb555b05dca5e361bd3ef3a 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 141 160 1.4E-15 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15865 a4833b760eb555b05dca5e361bd3ef3a 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 1 16 1.4E-15 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15865 a4833b760eb555b05dca5e361bd3ef3a 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 65 76 1.4E-15 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS09095 17827f42af51a253f498dfe3dfa71cfe 679 SUPERFAMILY SSF52540 212 256 1.78E-18 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS09095 17827f42af51a253f498dfe3dfa71cfe 679 SUPERFAMILY SSF52540 16 123 1.78E-18 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS09095 17827f42af51a253f498dfe3dfa71cfe 679 SUPERFAMILY SSF52540 44 95 5.32E-18 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS09095 17827f42af51a253f498dfe3dfa71cfe 679 SUPERFAMILY SSF52540 472 620 5.32E-18 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS09095 17827f42af51a253f498dfe3dfa71cfe 679 SUPERFAMILY SSF52540 202 273 5.32E-18 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS09095 17827f42af51a253f498dfe3dfa71cfe 679 SUPERFAMILY SSF52540 411 425 5.32E-18 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS09095 17827f42af51a253f498dfe3dfa71cfe 679 Gene3D G3DSA:3.40.50.300 8 93 1.1E-24 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS09095 17827f42af51a253f498dfe3dfa71cfe 679 Gene3D G3DSA:3.40.50.300 413 421 1.1E-24 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS09095 17827f42af51a253f498dfe3dfa71cfe 679 Gene3D G3DSA:3.40.50.300 202 274 1.1E-24 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS09095 17827f42af51a253f498dfe3dfa71cfe 679 Gene3D G3DSA:3.40.50.300 126 127 1.1E-24 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS09095 17827f42af51a253f498dfe3dfa71cfe 679 SMART SM00491 508 637 5.3E-44 T 06-07-2017 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 BWK49_RS09095 17827f42af51a253f498dfe3dfa71cfe 679 SMART SM00487 23 320 1.6E-7 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain BWK49_RS09095 17827f42af51a253f498dfe3dfa71cfe 679 Pfam PF13307 Helicase C-terminal domain 491 650 1.1E-25 T 06-07-2017 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 BWK49_RS09095 17827f42af51a253f498dfe3dfa71cfe 679 Pfam PF00270 DEAD/DEAH box helicase 40 92 8.8E-5 T 06-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 BWK49_RS04425 0065e66bbb9ac90bc47594b274a7c4f3 498 Pfam PF08817 WXG100 protein secretion system (Wss), protein YukD 16 97 2.4E-10 T 06-07-2017 IPR024962 YukD-like BWK49_RS04425 0065e66bbb9ac90bc47594b274a7c4f3 498 PIRSF PIRSF017804 8 496 8.9E-45 T 06-07-2017 IPR006707 Type VII secretion system membrane protein EccD BWK49_RS04425 0065e66bbb9ac90bc47594b274a7c4f3 498 TIGRFAM TIGR03920 T7SS_EccD: type VII secretion integral membrane protein EccD 23 494 5.5E-61 T 06-07-2017 IPR006707 Type VII secretion system membrane protein EccD BWK49_RS20425 12ae38f1ac38ffa188c99716a14b4d4d 569 Gene3D G3DSA:3.40.50.970 13 193 1.2E-37 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS20425 12ae38f1ac38ffa188c99716a14b4d4d 569 Gene3D G3DSA:3.40.50.1220 204 343 7.8E-14 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain BWK49_RS20425 12ae38f1ac38ffa188c99716a14b4d4d 569 SUPERFAMILY SSF52467 177 362 1.18E-17 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain BWK49_RS20425 12ae38f1ac38ffa188c99716a14b4d4d 569 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 12 190 4.7E-43 T 06-07-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 BWK49_RS20425 12ae38f1ac38ffa188c99716a14b4d4d 569 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 441 460 - T 06-07-2017 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 BWK49_RS20425 12ae38f1ac38ffa188c99716a14b4d4d 569 Gene3D G3DSA:3.40.50.970 385 568 6.3E-40 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS20425 12ae38f1ac38ffa188c99716a14b4d4d 569 SUPERFAMILY SSF52518 13 204 1.99E-37 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS20425 12ae38f1ac38ffa188c99716a14b4d4d 569 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 417 564 3.3E-27 T 06-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 BWK49_RS20425 12ae38f1ac38ffa188c99716a14b4d4d 569 SUPERFAMILY SSF52518 386 568 5.18E-36 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS13075 0efbece3963c327b1e2575974b807529 359 Pfam PF00953 Glycosyl transferase family 4 86 276 4.5E-38 T 06-07-2017 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 BWK49_RS13075 0efbece3963c327b1e2575974b807529 359 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 46 58 4.2E-5 T 06-07-2017 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 BWK49_RS13075 0efbece3963c327b1e2575974b807529 359 ProSitePatterns PS01347 MraY family signature 1. 46 58 - T 06-07-2017 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 BWK49_RS13075 0efbece3963c327b1e2575974b807529 359 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 3 350 22.857 T 06-07-2017 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 BWK49_RS13075 0efbece3963c327b1e2575974b807529 359 ProSitePatterns PS01348 MraY family signature 2. 179 190 - T 06-07-2017 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 BWK49_RS13075 0efbece3963c327b1e2575974b807529 359 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 15 342 3.4E-80 T 06-07-2017 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 BWK49_RS12315 f57172fe901584f493609f6426693a35 181 SUPERFAMILY SSF69118 1 171 2.09E-27 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 BWK49_RS12315 f57172fe901584f493609f6426693a35 181 Pfam PF02627 Carboxymuconolactone decarboxylase family 39 117 1.6E-7 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 BWK49_RS12315 f57172fe901584f493609f6426693a35 181 Gene3D G3DSA:1.20.1290.10 27 171 9.0E-24 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 BWK49_RS10840 6f5f73af31fb748ab7286c33fa0a1a82 234 Gene3D G3DSA:3.40.50.1820 4 231 3.9E-32 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS10840 6f5f73af31fb748ab7286c33fa0a1a82 234 Pfam PF12697 Alpha/beta hydrolase family 6 225 1.0E-15 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS10840 6f5f73af31fb748ab7286c33fa0a1a82 234 SUPERFAMILY SSF53474 6 229 3.73E-19 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS11465 7983c269cc2ac7df22b41626c90807dc 490 Gene3D G3DSA:3.90.1150.10 318 392 6.8E-7 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 BWK49_RS11465 7983c269cc2ac7df22b41626c90807dc 490 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 7 308 2.9E-47 T 06-07-2017 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 BWK49_RS11465 7983c269cc2ac7df22b41626c90807dc 490 Gene3D G3DSA:3.40.640.10 6 283 7.8E-78 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 BWK49_RS11465 7983c269cc2ac7df22b41626c90807dc 490 Gene3D G3DSA:3.90.100.10 408 484 2.4E-23 T 06-07-2017 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 BWK49_RS11465 7983c269cc2ac7df22b41626c90807dc 490 SUPERFAMILY SSF53383 7 382 2.75E-74 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase BWK49_RS11465 7983c269cc2ac7df22b41626c90807dc 490 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 414 464 4.9E-13 T 06-07-2017 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 BWK49_RS11465 7983c269cc2ac7df22b41626c90807dc 490 SUPERFAMILY SSF55904 340 485 6.54E-32 T 06-07-2017 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 BWK49_RS07920 de2d331679011791ea0a231b6db20ea6 65 Pfam PF09957 Bacterial antitoxin of type II TA system, VapB 1 42 2.3E-11 T 06-07-2017 IPR019239 Bacterial antitoxin of type II TA system, VapB BWK49_RS12540 dea2de319f4a1b6cd49493b67d121e57 382 Gene3D G3DSA:3.40.1390.30 238 330 1.0E-33 T 06-07-2017 BWK49_RS12540 dea2de319f4a1b6cd49493b67d121e57 382 Gene3D G3DSA:3.40.1390.30 114 129 1.0E-33 T 06-07-2017 BWK49_RS12540 dea2de319f4a1b6cd49493b67d121e57 382 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 3 358 2.3E-42 T 06-07-2017 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 BWK49_RS12540 dea2de319f4a1b6cd49493b67d121e57 382 Gene3D G3DSA:3.40.1390.30 3 113 2.3E-36 T 06-07-2017 BWK49_RS12540 dea2de319f4a1b6cd49493b67d121e57 382 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 7 352 4.7E-63 T 06-07-2017 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 BWK49_RS12540 dea2de319f4a1b6cd49493b67d121e57 382 Gene3D G3DSA:3.30.70.830 134 233 3.6E-40 T 06-07-2017 BWK49_RS12540 dea2de319f4a1b6cd49493b67d121e57 382 SUPERFAMILY SSF102705 3 370 1.57E-107 T 06-07-2017 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 BWK49_RS12540 dea2de319f4a1b6cd49493b67d121e57 382 PIRSF PIRSF037489 1 371 2.1E-138 T 06-07-2017 IPR017221 GTP cyclohydrolase 1 type 2//Nif3, bacteria BWK49_RS27620 0545572912a18450eec572967fbb6656 232 PIRSF PIRSF036625 1 232 9.2E-68 T 06-07-2017 IPR012074 GAF-ANTAR transcription anti-termination regulator, putative BWK49_RS27620 0545572912a18450eec572967fbb6656 232 Pfam PF13185 GAF domain 27 166 5.0E-13 T 06-07-2017 IPR003018 GAF domain GO:0005515 BWK49_RS27620 0545572912a18450eec572967fbb6656 232 Gene3D G3DSA:3.30.450.40 15 174 4.2E-19 T 06-07-2017 IPR029016 GAF domain-like BWK49_RS27620 0545572912a18450eec572967fbb6656 232 Gene3D G3DSA:1.10.10.10 175 229 7.8E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS27620 0545572912a18450eec572967fbb6656 232 SUPERFAMILY SSF52172 172 226 4.97E-9 T 06-07-2017 IPR011006 CheY-like superfamily BWK49_RS27620 0545572912a18450eec572967fbb6656 232 SMART SM01012 171 226 1.0E-20 T 06-07-2017 IPR005561 ANTAR domain GO:0003723 BWK49_RS27620 0545572912a18450eec572967fbb6656 232 SUPERFAMILY SSF55781 29 176 1.29E-18 T 06-07-2017 IPR029016 GAF domain-like BWK49_RS27620 0545572912a18450eec572967fbb6656 232 Pfam PF03861 ANTAR domain 174 226 2.0E-19 T 06-07-2017 IPR005561 ANTAR domain GO:0003723 BWK49_RS02695 bb21fa0b8c4e387e806e637e75e768ac 300 Gene3D G3DSA:3.30.750.24 175 267 1.0E-16 T 06-07-2017 IPR002645 STAS domain BWK49_RS02695 bb21fa0b8c4e387e806e637e75e768ac 300 Pfam PF01740 STAS domain 176 267 1.5E-10 T 06-07-2017 IPR002645 STAS domain BWK49_RS02695 bb21fa0b8c4e387e806e637e75e768ac 300 SUPERFAMILY SSF52091 174 283 3.14E-19 T 06-07-2017 IPR002645 STAS domain BWK49_RS07810 0b08befa25de37e263f385e6fc470ba4 291 Pfam PF01522 Polysaccharide deacetylase 47 162 2.4E-33 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 BWK49_RS07810 0b08befa25de37e263f385e6fc470ba4 291 SUPERFAMILY SSF88713 47 231 3.03E-58 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 BWK49_RS07810 0b08befa25de37e263f385e6fc470ba4 291 Gene3D G3DSA:3.20.20.370 45 231 2.2E-57 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 BWK49_RS10935 915cb12414ac25ef9ee45a53a478e24a 399 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 216 5.5E-22 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 BWK49_RS10935 915cb12414ac25ef9ee45a53a478e24a 399 SUPERFAMILY SSF47203 228 385 1.77E-25 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS10935 915cb12414ac25ef9ee45a53a478e24a 399 Gene3D G3DSA:1.20.140.10 218 388 8.4E-37 T 06-07-2017 BWK49_RS10935 915cb12414ac25ef9ee45a53a478e24a 399 Gene3D G3DSA:2.40.110.10 122 217 9.0E-37 T 06-07-2017 BWK49_RS10935 915cb12414ac25ef9ee45a53a478e24a 399 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 228 379 1.5E-31 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS10935 915cb12414ac25ef9ee45a53a478e24a 399 Gene3D G3DSA:1.10.540.10 1 119 2.4E-27 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS10935 915cb12414ac25ef9ee45a53a478e24a 399 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 118 1.9E-23 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS10935 915cb12414ac25ef9ee45a53a478e24a 399 SUPERFAMILY SSF56645 1 239 1.31E-70 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS00370 e8a251fc188262fb1d5363ee1967aec5 213 Pfam PF01965 DJ-1/PfpI family 3 166 4.5E-28 T 06-07-2017 IPR002818 DJ-1/PfpI BWK49_RS00370 e8a251fc188262fb1d5363ee1967aec5 213 Gene3D G3DSA:3.40.50.880 3 210 1.5E-64 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like BWK49_RS00370 e8a251fc188262fb1d5363ee1967aec5 213 SUPERFAMILY SSF52317 1 190 8.99E-46 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like BWK49_RS19425 b102385d100faaaac3c6b673ab5e6225 501 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 86 501 33.753 T 06-07-2017 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 BWK49_RS19425 b102385d100faaaac3c6b673ab5e6225 501 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 264 489 1.5E-35 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS19425 b102385d100faaaac3c6b673ab5e6225 501 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 264 500 6.3E-114 T 06-07-2017 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 BWK49_RS19425 b102385d100faaaac3c6b673ab5e6225 501 PRINTS PR00046 Major sigma-70 factor signature 316 324 3.7E-29 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS19425 b102385d100faaaac3c6b673ab5e6225 501 PRINTS PR00046 Major sigma-70 factor signature 476 487 3.7E-29 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS19425 b102385d100faaaac3c6b673ab5e6225 501 PRINTS PR00046 Major sigma-70 factor signature 440 452 3.7E-29 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS19425 b102385d100faaaac3c6b673ab5e6225 501 PRINTS PR00046 Major sigma-70 factor signature 292 305 3.7E-29 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS19425 b102385d100faaaac3c6b673ab5e6225 501 PRINTS PR00046 Major sigma-70 factor signature 461 476 3.7E-29 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS19425 b102385d100faaaac3c6b673ab5e6225 501 Gene3D G3DSA:1.10.10.10 431 501 1.7E-31 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS19425 b102385d100faaaac3c6b673ab5e6225 501 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 461 487 - T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS19425 b102385d100faaaac3c6b673ab5e6225 501 Pfam PF04539 Sigma-70 region 3 347 422 1.7E-28 T 06-07-2017 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS19425 b102385d100faaaac3c6b673ab5e6225 501 Pfam PF00140 Sigma-70 factor, region 1.2 199 232 4.4E-16 T 06-07-2017 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS19425 b102385d100faaaac3c6b673ab5e6225 501 SUPERFAMILY SSF88946 196 338 5.49E-54 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS19425 b102385d100faaaac3c6b673ab5e6225 501 Gene3D G3DSA:1.10.10.10 341 392 2.4E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS19425 b102385d100faaaac3c6b673ab5e6225 501 SUPERFAMILY SSF88659 400 500 2.05E-26 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS19425 b102385d100faaaac3c6b673ab5e6225 501 Pfam PF04542 Sigma-70 region 2 268 337 1.9E-22 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS19425 b102385d100faaaac3c6b673ab5e6225 501 Gene3D G3DSA:1.10.601.10 102 337 3.8E-63 T 06-07-2017 BWK49_RS19425 b102385d100faaaac3c6b673ab5e6225 501 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 292 305 - T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS19425 b102385d100faaaac3c6b673ab5e6225 501 Pfam PF04545 Sigma-70, region 4 436 489 2.4E-18 T 06-07-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS19425 b102385d100faaaac3c6b673ab5e6225 501 SUPERFAMILY SSF88659 341 414 1.96E-22 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS21855 ba7c7750d5a61a45c9401349907ada19 143 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 12 128 2.5E-25 T 06-07-2017 IPR024747 Pyridoxamine 5'-phosphate oxidase-related BWK49_RS21855 ba7c7750d5a61a45c9401349907ada19 143 SUPERFAMILY SSF50475 7 131 8.95E-29 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 BWK49_RS21855 ba7c7750d5a61a45c9401349907ada19 143 Gene3D G3DSA:2.30.110.10 4 137 7.1E-48 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 BWK49_RS10145 80af6e2b7cb9717266c1fdb7d39ffd37 386 SUPERFAMILY SSF56645 3 246 5.5E-73 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS10145 80af6e2b7cb9717266c1fdb7d39ffd37 386 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 120 1.2E-17 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS10145 80af6e2b7cb9717266c1fdb7d39ffd37 386 Gene3D G3DSA:2.40.110.10 125 222 1.2E-37 T 06-07-2017 BWK49_RS10145 80af6e2b7cb9717266c1fdb7d39ffd37 386 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 126 221 4.7E-21 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 BWK49_RS10145 80af6e2b7cb9717266c1fdb7d39ffd37 386 Gene3D G3DSA:1.10.540.10 1 123 1.1E-21 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS10145 80af6e2b7cb9717266c1fdb7d39ffd37 386 SUPERFAMILY SSF47203 233 386 1.3E-17 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS10145 80af6e2b7cb9717266c1fdb7d39ffd37 386 Gene3D G3DSA:1.20.140.10 223 385 1.5E-25 T 06-07-2017 BWK49_RS10145 80af6e2b7cb9717266c1fdb7d39ffd37 386 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 233 383 7.8E-18 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS10920 e3f5ec9cab8dc5979fa28617f50b6070 369 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 231 355 1.8E-27 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS10920 e3f5ec9cab8dc5979fa28617f50b6070 369 Gene3D G3DSA:1.20.140.10 229 357 5.2E-36 T 06-07-2017 BWK49_RS10920 e3f5ec9cab8dc5979fa28617f50b6070 369 Gene3D G3DSA:2.40.110.10 124 198 7.0E-13 T 06-07-2017 BWK49_RS10920 e3f5ec9cab8dc5979fa28617f50b6070 369 Gene3D G3DSA:1.10.540.10 1 118 2.2E-20 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS10920 e3f5ec9cab8dc5979fa28617f50b6070 369 SUPERFAMILY SSF56645 1 215 6.54E-41 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS10920 e3f5ec9cab8dc5979fa28617f50b6070 369 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 124 199 3.7E-9 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 BWK49_RS10920 e3f5ec9cab8dc5979fa28617f50b6070 369 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 117 4.6E-18 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS10920 e3f5ec9cab8dc5979fa28617f50b6070 369 SUPERFAMILY SSF47203 226 362 2.09E-37 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS22280 c277874cd0cf85bd89d3db4758c89c9e 235 PIRSF PIRSF036625 2 235 3.8E-56 T 06-07-2017 IPR012074 GAF-ANTAR transcription anti-termination regulator, putative BWK49_RS22280 c277874cd0cf85bd89d3db4758c89c9e 235 SMART SM01012 169 224 1.6E-23 T 06-07-2017 IPR005561 ANTAR domain GO:0003723 BWK49_RS22280 c277874cd0cf85bd89d3db4758c89c9e 235 Pfam PF03861 ANTAR domain 172 224 6.7E-20 T 06-07-2017 IPR005561 ANTAR domain GO:0003723 BWK49_RS22280 c277874cd0cf85bd89d3db4758c89c9e 235 SUPERFAMILY SSF55781 36 174 1.02E-15 T 06-07-2017 IPR029016 GAF domain-like BWK49_RS22280 c277874cd0cf85bd89d3db4758c89c9e 235 Gene3D G3DSA:3.30.450.40 37 173 3.0E-12 T 06-07-2017 IPR029016 GAF domain-like BWK49_RS22280 c277874cd0cf85bd89d3db4758c89c9e 235 Gene3D G3DSA:1.10.10.10 174 227 1.5E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS22280 c277874cd0cf85bd89d3db4758c89c9e 235 Pfam PF13185 GAF domain 30 162 4.9E-10 T 06-07-2017 IPR003018 GAF domain GO:0005515 BWK49_RS22280 c277874cd0cf85bd89d3db4758c89c9e 235 SUPERFAMILY SSF52172 164 224 4.32E-10 T 06-07-2017 IPR011006 CheY-like superfamily BWK49_RS25960 866add812c2f948b45594b495674a538 381 Gene3D G3DSA:2.40.110.10 126 219 3.7E-39 T 06-07-2017 BWK49_RS25960 866add812c2f948b45594b495674a538 381 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 338 357 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 BWK49_RS25960 866add812c2f948b45594b495674a538 381 Gene3D G3DSA:1.10.540.10 4 122 1.5E-30 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS25960 866add812c2f948b45594b495674a538 381 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 126 218 2.1E-26 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 BWK49_RS25960 866add812c2f948b45594b495674a538 381 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 231 379 1.9E-41 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS25960 866add812c2f948b45594b495674a538 381 Gene3D G3DSA:1.20.140.10 220 379 1.0E-53 T 06-07-2017 BWK49_RS25960 866add812c2f948b45594b495674a538 381 SUPERFAMILY SSF47203 230 379 1.47E-46 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS25960 866add812c2f948b45594b495674a538 381 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 121 1.5E-27 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS25960 866add812c2f948b45594b495674a538 381 SUPERFAMILY SSF56645 4 243 6.28E-78 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS12750 818b0ab476a0cb72478405e7e2d3d330 402 Pfam PF00589 Phage integrase family 193 357 3.4E-14 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 BWK49_RS12750 818b0ab476a0cb72478405e7e2d3d330 402 Gene3D G3DSA:1.10.150.130 87 182 8.3E-17 T 06-07-2017 IPR023109 Integrase/recombinase, N-terminal BWK49_RS12750 818b0ab476a0cb72478405e7e2d3d330 402 SUPERFAMILY SSF56349 86 360 3.83E-51 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 BWK49_RS12750 818b0ab476a0cb72478405e7e2d3d330 402 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 87 140 4.0E-5 T 06-07-2017 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 BWK49_RS12750 818b0ab476a0cb72478405e7e2d3d330 402 Gene3D G3DSA:1.10.443.10 192 363 2.3E-29 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 BWK49_RS24495 29694380cb692fd39f89d344704f41ca 336 Gene3D G3DSA:3.40.50.300 4 236 1.9E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS24495 29694380cb692fd39f89d344704f41ca 336 Pfam PF00005 ABC transporter 21 168 9.1E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 BWK49_RS24495 29694380cb692fd39f89d344704f41ca 336 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 BWK49_RS24495 29694380cb692fd39f89d344704f41ca 336 SUPERFAMILY SSF52540 5 232 4.78E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS24495 29694380cb692fd39f89d344704f41ca 336 SMART SM00382 29 225 1.2E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS13200 fe5d54b1114928966ce08c6bc45ca8fb 411 Hamap MF_01697 L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase [mshC]. 9 411 52.373 T 06-07-2017 IPR017812 Mycothiol ligase MshC GO:0010125|GO:0035446 BWK49_RS13200 fe5d54b1114928966ce08c6bc45ca8fb 411 SUPERFAMILY SSF52374 26 335 5.63E-68 T 06-07-2017 BWK49_RS13200 fe5d54b1114928966ce08c6bc45ca8fb 411 Gene3D G3DSA:3.40.50.620 36 328 1.8E-73 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold BWK49_RS13200 fe5d54b1114928966ce08c6bc45ca8fb 411 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 243 264 2.8E-25 T 06-07-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 BWK49_RS13200 fe5d54b1114928966ce08c6bc45ca8fb 411 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 40 51 2.8E-25 T 06-07-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 BWK49_RS13200 fe5d54b1114928966ce08c6bc45ca8fb 411 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 76 85 2.8E-25 T 06-07-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 BWK49_RS13200 fe5d54b1114928966ce08c6bc45ca8fb 411 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 212 230 2.8E-25 T 06-07-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 BWK49_RS13200 fe5d54b1114928966ce08c6bc45ca8fb 411 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 36 335 2.4E-81 T 06-07-2017 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 BWK49_RS13200 fe5d54b1114928966ce08c6bc45ca8fb 411 Gene3D G3DSA:1.20.120.640 331 409 4.2E-5 T 06-07-2017 BWK49_RS13200 fe5d54b1114928966ce08c6bc45ca8fb 411 TIGRFAM TIGR03447 mycothiol_MshC: cysteine--1-D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase 2 411 1.7E-214 T 06-07-2017 IPR017812 Mycothiol ligase MshC GO:0010125|GO:0035446 BWK49_RS27740 88bb6d5e122565e081cdfd57ae91b9f2 1162 SUPERFAMILY SSF56801 27 625 1.31E-84 T 06-07-2017 BWK49_RS27740 88bb6d5e122565e081cdfd57ae91b9f2 1162 ProSitePatterns PS00455 Putative AMP-binding domain signature. 235 246 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS27740 88bb6d5e122565e081cdfd57ae91b9f2 1162 Gene3D G3DSA:3.40.50.720 764 1035 5.1E-26 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS27740 88bb6d5e122565e081cdfd57ae91b9f2 1162 SUPERFAMILY SSF51735 764 1071 1.36E-27 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS27740 88bb6d5e122565e081cdfd57ae91b9f2 1162 Gene3D G3DSA:2.30.38.10 437 491 1.2E-11 T 06-07-2017 BWK49_RS27740 88bb6d5e122565e081cdfd57ae91b9f2 1162 Gene3D G3DSA:3.40.50.980 28 241 5.8E-26 T 06-07-2017 BWK49_RS27740 88bb6d5e122565e081cdfd57ae91b9f2 1162 Gene3D G3DSA:3.30.300.30 500 614 6.5E-4 T 06-07-2017 BWK49_RS27740 88bb6d5e122565e081cdfd57ae91b9f2 1162 Gene3D G3DSA:1.10.1200.10 638 714 2.0E-8 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS27740 88bb6d5e122565e081cdfd57ae91b9f2 1162 Pfam PF00501 AMP-binding enzyme 68 498 1.3E-57 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS27740 88bb6d5e122565e081cdfd57ae91b9f2 1162 SUPERFAMILY SSF47336 643 723 4.45E-10 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS27740 88bb6d5e122565e081cdfd57ae91b9f2 1162 Gene3D G3DSA:3.40.50.980 242 409 2.9E-19 T 06-07-2017 BWK49_RS27740 88bb6d5e122565e081cdfd57ae91b9f2 1162 TIGRFAM TIGR01746 Thioester-redct: thioester reductase domain 764 1160 8.4E-86 T 06-07-2017 IPR010080 Thioester reductase-like domain BWK49_RS27740 88bb6d5e122565e081cdfd57ae91b9f2 1162 Pfam PF07993 Male sterility protein 767 1028 3.9E-52 T 06-07-2017 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 BWK49_RS27740 88bb6d5e122565e081cdfd57ae91b9f2 1162 Pfam PF00550 Phosphopantetheine attachment site 644 709 6.5E-9 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS27740 88bb6d5e122565e081cdfd57ae91b9f2 1162 SMART SM00823 Phosphopantetheine attachment site 641 713 8.2E-4 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS06505 c746d2c56597725b79ddbc299ef59265 201 Gene3D G3DSA:3.40.50.150 39 186 3.0E-30 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS06505 c746d2c56597725b79ddbc299ef59265 201 Pfam PF13649 Methyltransferase domain 47 140 4.5E-18 T 06-07-2017 BWK49_RS06505 c746d2c56597725b79ddbc299ef59265 201 SUPERFAMILY SSF53335 11 179 2.63E-31 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS04015 312d7e907101474cb90f01bb3185a662 336 Pfam PF04261 Dyp-type peroxidase family 7 303 4.3E-99 T 06-07-2017 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 BWK49_RS04015 312d7e907101474cb90f01bb3185a662 336 SUPERFAMILY SSF54909 5 306 2.32E-103 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel BWK49_RS04015 312d7e907101474cb90f01bb3185a662 336 TIGRFAM TIGR04537 encap_target: encapsulation C-terminal sorting signal 323 333 0.067 T 06-07-2017 BWK49_RS04015 312d7e907101474cb90f01bb3185a662 336 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 7 303 1.4E-87 T 06-07-2017 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 BWK49_RS09215 730745082e8ab67e8659778da0a6cf46 397 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 126 229 5.9E-22 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 BWK49_RS09215 730745082e8ab67e8659778da0a6cf46 397 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 11 122 6.7E-33 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS09215 730745082e8ab67e8659778da0a6cf46 397 SUPERFAMILY SSF56645 8 252 9.95E-70 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS09215 730745082e8ab67e8659778da0a6cf46 397 Gene3D G3DSA:1.20.140.10 231 395 1.3E-56 T 06-07-2017 BWK49_RS09215 730745082e8ab67e8659778da0a6cf46 397 Gene3D G3DSA:1.10.540.10 8 123 4.0E-40 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS09215 730745082e8ab67e8659778da0a6cf46 397 Gene3D G3DSA:2.40.110.10 125 230 9.9E-30 T 06-07-2017 BWK49_RS09215 730745082e8ab67e8659778da0a6cf46 397 SUPERFAMILY SSF47203 243 394 4.19E-52 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS09215 730745082e8ab67e8659778da0a6cf46 397 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 243 392 1.5E-45 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS19535 47352437629e7f80615eed9e19e9abb0 288 Gene3D G3DSA:3.10.310.10 138 266 7.9E-32 T 06-07-2017 BWK49_RS19535 47352437629e7f80615eed9e19e9abb0 288 Pfam PF01678 Diaminopimelate epimerase 3 141 1.2E-37 T 06-07-2017 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 BWK49_RS19535 47352437629e7f80615eed9e19e9abb0 288 Pfam PF01678 Diaminopimelate epimerase 158 274 2.8E-22 T 06-07-2017 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 BWK49_RS19535 47352437629e7f80615eed9e19e9abb0 288 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 78 92 - T 06-07-2017 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 BWK49_RS19535 47352437629e7f80615eed9e19e9abb0 288 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 1 282 29.322 T 06-07-2017 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 BWK49_RS19535 47352437629e7f80615eed9e19e9abb0 288 SUPERFAMILY SSF54506 1 139 2.56E-30 T 06-07-2017 BWK49_RS19535 47352437629e7f80615eed9e19e9abb0 288 SUPERFAMILY SSF54506 150 280 1.31E-28 T 06-07-2017 BWK49_RS19535 47352437629e7f80615eed9e19e9abb0 288 Gene3D G3DSA:3.10.310.10 1 137 7.6E-36 T 06-07-2017 BWK49_RS19535 47352437629e7f80615eed9e19e9abb0 288 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 2 281 1.8E-75 T 06-07-2017 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 BWK49_RS24885 7fae1e2801da2949640cb8080eb2776c 245 Gene3D G3DSA:3.40.50.720 2 226 6.7E-63 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS24885 7fae1e2801da2949640cb8080eb2776c 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 59 70 6.7E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS24885 7fae1e2801da2949640cb8080eb2776c 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 107 123 6.7E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS24885 7fae1e2801da2949640cb8080eb2776c 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 171 6.7E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS24885 7fae1e2801da2949640cb8080eb2776c 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 189 209 6.7E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS24885 7fae1e2801da2949640cb8080eb2776c 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 152 6.7E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS24885 7fae1e2801da2949640cb8080eb2776c 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 2 19 6.7E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS24885 7fae1e2801da2949640cb8080eb2776c 245 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 120 148 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS24885 7fae1e2801da2949640cb8080eb2776c 245 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 10 223 3.9E-46 T 06-07-2017 BWK49_RS24885 7fae1e2801da2949640cb8080eb2776c 245 SUPERFAMILY SSF51735 2 225 6.22E-61 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS23470 09fe1497fd7ef7698621728c15371dfb 413 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 95 316 1.7E-37 T 06-07-2017 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 BWK49_RS23470 09fe1497fd7ef7698621728c15371dfb 413 Gene3D G3DSA:3.40.710.10 93 337 6.9E-72 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like BWK49_RS23470 09fe1497fd7ef7698621728c15371dfb 413 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 126 137 1.2E-6 T 06-07-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 BWK49_RS23470 09fe1497fd7ef7698621728c15371dfb 413 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 174 191 1.2E-6 T 06-07-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 BWK49_RS23470 09fe1497fd7ef7698621728c15371dfb 413 SUPERFAMILY SSF56601 80 336 6.76E-56 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like BWK49_RS21255 aec9c205e0de8a06712c02d3baae3251 323 Pfam PF08241 Methyltransferase domain 78 175 3.6E-23 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 BWK49_RS21255 aec9c205e0de8a06712c02d3baae3251 323 Gene3D G3DSA:3.40.50.150 33 322 5.1E-40 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS21255 aec9c205e0de8a06712c02d3baae3251 323 SUPERFAMILY SSF53335 37 187 1.37E-38 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS21255 aec9c205e0de8a06712c02d3baae3251 323 SUPERFAMILY SSF53335 233 322 1.37E-38 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS16775 ec356c86fc202ea6a245dd2b7154e934 213 SUPERFAMILY SSF51735 1 191 7.89E-34 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS16775 ec356c86fc202ea6a245dd2b7154e934 213 Pfam PF13460 NAD(P)H-binding 8 190 1.2E-52 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS16775 ec356c86fc202ea6a245dd2b7154e934 213 Gene3D G3DSA:3.40.50.720 1 191 3.6E-39 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS05485 61860441e8a4f3821de738a22d2004df 297 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 156 1.6E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05485 61860441e8a4f3821de738a22d2004df 297 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 187 204 1.6E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05485 61860441e8a4f3821de738a22d2004df 297 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 93 104 1.6E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05485 61860441e8a4f3821de738a22d2004df 297 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 185 1.6E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05485 61860441e8a4f3821de738a22d2004df 297 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 1.6E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05485 61860441e8a4f3821de738a22d2004df 297 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 1.6E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05485 61860441e8a4f3821de738a22d2004df 297 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 153 181 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS05485 61860441e8a4f3821de738a22d2004df 297 Pfam PF00106 short chain dehydrogenase 10 205 2.7E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05485 61860441e8a4f3821de738a22d2004df 297 SUPERFAMILY SSF51735 4 247 4.34E-66 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS05485 61860441e8a4f3821de738a22d2004df 297 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 200 7.4E-4 T 06-07-2017 BWK49_RS05485 61860441e8a4f3821de738a22d2004df 297 Gene3D G3DSA:3.40.50.720 5 249 5.2E-65 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS05485 61860441e8a4f3821de738a22d2004df 297 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 154 5.8E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05485 61860441e8a4f3821de738a22d2004df 297 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 93 104 5.8E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05485 61860441e8a4f3821de738a22d2004df 297 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 166 185 5.8E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS11380 742993c19dd5e404f140dca97213737f 2191 SUPERFAMILY SSF52777 1083 1256 1.78E-45 T 06-07-2017 BWK49_RS11380 742993c19dd5e404f140dca97213737f 2191 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1016 1031 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site BWK49_RS11380 742993c19dd5e404f140dca97213737f 2191 Gene3D G3DSA:3.30.300.30 1960 2083 1.2E-26 T 06-07-2017 BWK49_RS11380 742993c19dd5e404f140dca97213737f 2191 ProSitePatterns PS00455 Putative AMP-binding domain signature. 626 637 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS11380 742993c19dd5e404f140dca97213737f 2191 Gene3D G3DSA:3.40.50.980 494 634 4.4E-48 T 06-07-2017 BWK49_RS11380 742993c19dd5e404f140dca97213737f 2191 Gene3D G3DSA:3.40.50.980 1554 1716 4.2E-39 T 06-07-2017 BWK49_RS11380 742993c19dd5e404f140dca97213737f 2191 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1709 1720 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS11380 742993c19dd5e404f140dca97213737f 2191 SUPERFAMILY SSF52777 45 227 7.56E-33 T 06-07-2017 BWK49_RS11380 742993c19dd5e404f140dca97213737f 2191 SUPERFAMILY SSF52777 220 464 1.45E-40 T 06-07-2017 BWK49_RS11380 742993c19dd5e404f140dca97213737f 2191 Pfam PF00550 Phosphopantetheine attachment site 2080 2142 3.9E-10 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS11380 742993c19dd5e404f140dca97213737f 2191 Pfam PF00550 Phosphopantetheine attachment site 995 1057 2.6E-12 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS11380 742993c19dd5e404f140dca97213737f 2191 SUPERFAMILY SSF56801 1519 2090 3.4E-131 T 06-07-2017 BWK49_RS11380 742993c19dd5e404f140dca97213737f 2191 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 521 905 4.8E-125 T 06-07-2017 IPR010071 Amino acid adenylation domain BWK49_RS11380 742993c19dd5e404f140dca97213737f 2191 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1583 1988 2.6E-109 T 06-07-2017 IPR010071 Amino acid adenylation domain BWK49_RS11380 742993c19dd5e404f140dca97213737f 2191 SUPERFAMILY SSF52777 1270 1523 1.78E-50 T 06-07-2017 BWK49_RS11380 742993c19dd5e404f140dca97213737f 2191 Pfam PF00668 Condensation domain 1080 1381 1.7E-50 T 06-07-2017 IPR001242 Condensation domain BWK49_RS11380 742993c19dd5e404f140dca97213737f 2191 Pfam PF00668 Condensation domain 45 330 8.5E-41 T 06-07-2017 IPR001242 Condensation domain BWK49_RS11380 742993c19dd5e404f140dca97213737f 2191 SUPERFAMILY SSF56801 460 1004 2.49E-156 T 06-07-2017 BWK49_RS11380 742993c19dd5e404f140dca97213737f 2191 Pfam PF13745 HxxPF-repeated domain 1403 1506 1.4E-19 T 06-07-2017 BWK49_RS11380 742993c19dd5e404f140dca97213737f 2191 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2102 2117 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site BWK49_RS11380 742993c19dd5e404f140dca97213737f 2191 Gene3D G3DSA:3.40.50.980 635 793 2.1E-41 T 06-07-2017 BWK49_RS11380 742993c19dd5e404f140dca97213737f 2191 Gene3D G3DSA:3.40.50.980 1717 1866 6.4E-29 T 06-07-2017 BWK49_RS11380 742993c19dd5e404f140dca97213737f 2191 Gene3D G3DSA:2.30.38.10 1875 1955 1.9E-27 T 06-07-2017 BWK49_RS11380 742993c19dd5e404f140dca97213737f 2191 Gene3D G3DSA:2.30.38.10 794 871 9.2E-27 T 06-07-2017 BWK49_RS11380 742993c19dd5e404f140dca97213737f 2191 SMART SM00823 Phosphopantetheine attachment site 2078 2146 3.0E-4 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS11380 742993c19dd5e404f140dca97213737f 2191 SMART SM00823 Phosphopantetheine attachment site 992 1061 3.8E-6 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS11380 742993c19dd5e404f140dca97213737f 2191 Gene3D G3DSA:3.30.300.30 875 978 7.7E-31 T 06-07-2017 BWK49_RS11380 742993c19dd5e404f140dca97213737f 2191 Pfam PF13193 AMP-binding enzyme C-terminal domain 889 967 7.3E-10 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS11380 742993c19dd5e404f140dca97213737f 2191 Pfam PF13193 AMP-binding enzyme C-terminal domain 1973 2053 1.9E-8 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS11380 742993c19dd5e404f140dca97213737f 2191 Pfam PF00501 AMP-binding enzyme 502 881 5.6E-96 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS11380 742993c19dd5e404f140dca97213737f 2191 Pfam PF00501 AMP-binding enzyme 1569 1965 1.1E-85 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS11380 742993c19dd5e404f140dca97213737f 2191 SUPERFAMILY SSF47336 2072 2142 2.22E-16 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS11380 742993c19dd5e404f140dca97213737f 2191 SUPERFAMILY SSF47336 984 1058 8.77E-18 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS11380 742993c19dd5e404f140dca97213737f 2191 Gene3D G3DSA:1.10.1200.10 980 1062 1.5E-24 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS11380 742993c19dd5e404f140dca97213737f 2191 Gene3D G3DSA:1.10.1200.10 2084 2147 1.7E-24 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS08335 614187b427fc748abb3e6ca95ef876bf 395 SUPERFAMILY SSF140459 3 175 6.54E-60 T 06-07-2017 BWK49_RS08335 614187b427fc748abb3e6ca95ef876bf 395 Pfam PF00823 PPE family 6 162 2.8E-59 T 06-07-2017 IPR000030 PPE family BWK49_RS08335 614187b427fc748abb3e6ca95ef876bf 395 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 302 391 4.0E-13 T 06-07-2017 IPR022171 PPE family, C-terminal BWK49_RS19210 f4c9263532bc33e7126b0e68c59b6341 273 Gene3D G3DSA:3.40.50.720 7 272 5.5E-75 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS19210 f4c9263532bc33e7126b0e68c59b6341 273 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 161 2.5E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS19210 f4c9263532bc33e7126b0e68c59b6341 273 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 173 192 2.5E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS19210 f4c9263532bc33e7126b0e68c59b6341 273 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 100 111 2.5E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS19210 f4c9263532bc33e7126b0e68c59b6341 273 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 19 271 8.4E-51 T 06-07-2017 BWK49_RS19210 f4c9263532bc33e7126b0e68c59b6341 273 TIGRFAM TIGR03971 SDR_subfam_1: SDR family mycofactocin-dependent oxidoreductase 10 272 2.2E-103 T 06-07-2017 IPR023985 Mycofactocin-dependent oxidoreductase BWK49_RS19210 f4c9263532bc33e7126b0e68c59b6341 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 194 211 4.1E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS19210 f4c9263532bc33e7126b0e68c59b6341 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 4.1E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS19210 f4c9263532bc33e7126b0e68c59b6341 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 100 111 4.1E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS19210 f4c9263532bc33e7126b0e68c59b6341 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 163 4.1E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS19210 f4c9263532bc33e7126b0e68c59b6341 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 234 254 4.1E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS19210 f4c9263532bc33e7126b0e68c59b6341 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 192 4.1E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS19210 f4c9263532bc33e7126b0e68c59b6341 273 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 160 188 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS19210 f4c9263532bc33e7126b0e68c59b6341 273 SUPERFAMILY SSF51735 8 272 3.38E-71 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS22905 a11729fb695e41621d5fdc240f88030a 942 SMART SM00958 224 336 3.0E-61 T 06-07-2017 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 BWK49_RS22905 a11729fb695e41621d5fdc240f88030a 942 PRINTS PR00906 SecA protein signature 97 111 8.3E-70 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 BWK49_RS22905 a11729fb695e41621d5fdc240f88030a 942 PRINTS PR00906 SecA protein signature 317 339 8.3E-70 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 BWK49_RS22905 a11729fb695e41621d5fdc240f88030a 942 PRINTS PR00906 SecA protein signature 354 371 8.3E-70 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 BWK49_RS22905 a11729fb695e41621d5fdc240f88030a 942 PRINTS PR00906 SecA protein signature 113 123 8.3E-70 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 BWK49_RS22905 a11729fb695e41621d5fdc240f88030a 942 PRINTS PR00906 SecA protein signature 166 186 8.3E-70 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 BWK49_RS22905 a11729fb695e41621d5fdc240f88030a 942 PRINTS PR00906 SecA protein signature 59 83 8.3E-70 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 BWK49_RS22905 a11729fb695e41621d5fdc240f88030a 942 PRINTS PR00906 SecA protein signature 391 404 8.3E-70 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 BWK49_RS22905 a11729fb695e41621d5fdc240f88030a 942 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 24 817 0.0 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 BWK49_RS22905 a11729fb695e41621d5fdc240f88030a 942 Gene3D G3DSA:3.40.50.300 347 394 2.7E-122 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS22905 a11729fb695e41621d5fdc240f88030a 942 Gene3D G3DSA:3.40.50.300 2 224 2.7E-122 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS22905 a11729fb695e41621d5fdc240f88030a 942 Pfam PF07516 SecA Wing and Scaffold domain 610 830 1.2E-67 T 06-07-2017 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 BWK49_RS22905 a11729fb695e41621d5fdc240f88030a 942 SUPERFAMILY SSF81767 223 346 4.45E-43 T 06-07-2017 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 BWK49_RS22905 a11729fb695e41621d5fdc240f88030a 942 Gene3D G3DSA:3.90.1440.10 228 346 5.8E-47 T 06-07-2017 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 BWK49_RS22905 a11729fb695e41621d5fdc240f88030a 942 SUPERFAMILY SSF52540 395 611 4.71E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS22905 a11729fb695e41621d5fdc240f88030a 942 Pfam PF07517 SecA DEAD-like domain 6 379 9.8E-127 T 06-07-2017 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 BWK49_RS22905 a11729fb695e41621d5fdc240f88030a 942 SUPERFAMILY SSF52540 4 224 6.85E-79 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS22905 a11729fb695e41621d5fdc240f88030a 942 SUPERFAMILY SSF52540 346 393 6.85E-79 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS22905 a11729fb695e41621d5fdc240f88030a 942 Hamap MF_01382 Protein translocase subunit SecA [secA]. 1 833 19.706 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 BWK49_RS22905 a11729fb695e41621d5fdc240f88030a 942 Gene3D G3DSA:1.10.3060.10 641 831 3.3E-62 T 06-07-2017 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 BWK49_RS22905 a11729fb695e41621d5fdc240f88030a 942 Pfam PF01043 SecA preprotein cross-linking domain 229 336 1.0E-34 T 06-07-2017 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 BWK49_RS22905 a11729fb695e41621d5fdc240f88030a 942 SMART SM00957 2 380 7.6E-277 T 06-07-2017 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 BWK49_RS22905 a11729fb695e41621d5fdc240f88030a 942 ProSitePatterns PS01312 SecA family signature. 478 493 - T 06-07-2017 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 BWK49_RS22905 a11729fb695e41621d5fdc240f88030a 942 Gene3D G3DSA:3.40.50.300 395 612 6.4E-90 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS22905 a11729fb695e41621d5fdc240f88030a 942 SUPERFAMILY SSF81886 614 831 4.71E-74 T 06-07-2017 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 BWK49_RS12270 0a3e1726a3553b2ce0ac237099cd49e6 198 SUPERFAMILY SSF46689 8 92 6.48E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS12270 0a3e1726a3553b2ce0ac237099cd49e6 198 Pfam PF13305 WHG domain 95 177 1.2E-19 T 06-07-2017 IPR025996 WHG domain BWK49_RS12270 0a3e1726a3553b2ce0ac237099cd49e6 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 4.2E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS12270 0a3e1726a3553b2ce0ac237099cd49e6 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 4.2E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS12270 0a3e1726a3553b2ce0ac237099cd49e6 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 66 1.5E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS12270 0a3e1726a3553b2ce0ac237099cd49e6 198 SUPERFAMILY SSF48498 91 194 7.67E-23 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS12270 0a3e1726a3553b2ce0ac237099cd49e6 198 Gene3D G3DSA:1.10.357.10 7 194 1.8E-43 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS11470 c4160dc816d26e0b18bc186aec6fb768 496 SUPERFAMILY SSF75304 22 478 1.31E-109 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 BWK49_RS11470 c4160dc816d26e0b18bc186aec6fb768 496 Pfam PF01425 Amidase 41 460 5.3E-113 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 BWK49_RS11470 c4160dc816d26e0b18bc186aec6fb768 496 Gene3D G3DSA:3.90.1300.10 22 477 1.1E-112 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 BWK49_RS11470 c4160dc816d26e0b18bc186aec6fb768 496 ProSitePatterns PS00571 Amidases signature. 165 196 - T 06-07-2017 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 BWK49_RS01950 c630bfbf7e32e2dc9fae3fbac450111c 129 TIGRFAM TIGR02425 decarb_PcaC: 4-carboxymuconolactone decarboxylase 5 124 1.1E-50 T 06-07-2017 IPR012788 4-carboxymuconolactone decarboxylase KEGG: 00362+4.1.1.44 BWK49_RS01950 c630bfbf7e32e2dc9fae3fbac450111c 129 SUPERFAMILY SSF69118 6 123 1.83E-34 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 BWK49_RS01950 c630bfbf7e32e2dc9fae3fbac450111c 129 Gene3D G3DSA:1.20.1290.10 5 126 1.3E-27 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 BWK49_RS01950 c630bfbf7e32e2dc9fae3fbac450111c 129 Pfam PF02627 Carboxymuconolactone decarboxylase family 37 119 7.3E-25 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 BWK49_RS06790 cf91ed1ba4774fce88e868d99505b003 406 SUPERFAMILY SSF53901 246 392 2.76E-26 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS06790 cf91ed1ba4774fce88e868d99505b003 406 Gene3D G3DSA:3.40.47.10 196 233 1.0E-13 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS06790 cf91ed1ba4774fce88e868d99505b003 406 Gene3D G3DSA:3.40.47.10 19 120 1.0E-13 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS06790 cf91ed1ba4774fce88e868d99505b003 406 SUPERFAMILY SSF53901 7 241 3.01E-31 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS06790 cf91ed1ba4774fce88e868d99505b003 406 PIRSF PIRSF000429 1 404 3.3E-55 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 BWK49_RS06790 cf91ed1ba4774fce88e868d99505b003 406 Pfam PF02803 Thiolase, C-terminal domain 281 379 6.6E-9 T 06-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 BWK49_RS06790 cf91ed1ba4774fce88e868d99505b003 406 Pfam PF00108 Thiolase, N-terminal domain 26 233 4.9E-10 T 06-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 BWK49_RS06790 cf91ed1ba4774fce88e868d99505b003 406 Gene3D G3DSA:3.40.47.10 263 398 1.2E-18 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS06790 cf91ed1ba4774fce88e868d99505b003 406 Gene3D G3DSA:3.40.47.10 153 191 1.2E-18 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS24000 5f1cfc77454d1b0eea2cbb58cb2b470a 347 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 250 321 2.0E-34 T 06-07-2017 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 BWK49_RS24000 5f1cfc77454d1b0eea2cbb58cb2b470a 347 Gene3D G3DSA:3.30.1360.10 7 61 1.9E-10 T 06-07-2017 BWK49_RS24000 5f1cfc77454d1b0eea2cbb58cb2b470a 347 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 24 218 1.9E-20 T 06-07-2017 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 BWK49_RS24000 5f1cfc77454d1b0eea2cbb58cb2b470a 347 Gene3D G3DSA:1.10.150.20 248 320 3.5E-32 T 06-07-2017 BWK49_RS24000 5f1cfc77454d1b0eea2cbb58cb2b470a 347 SUPERFAMILY SSF47789 247 319 2.62E-24 T 06-07-2017 BWK49_RS24000 5f1cfc77454d1b0eea2cbb58cb2b470a 347 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 1 311 34.888 T 06-07-2017 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 BWK49_RS24000 5f1cfc77454d1b0eea2cbb58cb2b470a 347 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 57 149 1.2E-25 T 06-07-2017 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 BWK49_RS24000 5f1cfc77454d1b0eea2cbb58cb2b470a 347 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 19 310 7.9E-116 T 06-07-2017 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 BWK49_RS24000 5f1cfc77454d1b0eea2cbb58cb2b470a 347 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 242 302 8.7E-27 T 06-07-2017 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 BWK49_RS24000 5f1cfc77454d1b0eea2cbb58cb2b470a 347 SUPERFAMILY SSF56553 48 169 9.94E-43 T 06-07-2017 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 BWK49_RS24000 5f1cfc77454d1b0eea2cbb58cb2b470a 347 Gene3D G3DSA:2.170.120.12 62 168 3.8E-46 T 06-07-2017 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 BWK49_RS24000 5f1cfc77454d1b0eea2cbb58cb2b470a 347 SUPERFAMILY SSF55257 14 48 3.53E-26 T 06-07-2017 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 BWK49_RS24000 5f1cfc77454d1b0eea2cbb58cb2b470a 347 SUPERFAMILY SSF55257 170 220 3.53E-26 T 06-07-2017 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 BWK49_RS24000 5f1cfc77454d1b0eea2cbb58cb2b470a 347 SMART SM00662 18 225 7.0E-99 T 06-07-2017 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 BWK49_RS19480 2bae81cc1309892817411bcf00598836 278 Pfam PF13365 Trypsin-like peptidase domain 80 224 4.8E-9 T 06-07-2017 BWK49_RS19480 2bae81cc1309892817411bcf00598836 278 Gene3D G3DSA:2.40.10.10 75 154 9.2E-9 T 06-07-2017 BWK49_RS19480 2bae81cc1309892817411bcf00598836 278 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 94 99 - T 06-07-2017 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 BWK49_RS19480 2bae81cc1309892817411bcf00598836 278 SUPERFAMILY SSF50494 71 246 4.71E-19 T 06-07-2017 IPR009003 Peptidase S1, PA clan BWK49_RS28240 2cf8dcbd3d4522be17a69f03c15dfcb3 951 SUPERFAMILY SSF82866 700 926 1.44E-27 T 06-07-2017 BWK49_RS28240 2cf8dcbd3d4522be17a69f03c15dfcb3 951 Pfam PF03176 MMPL family 48 376 4.9E-94 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 BWK49_RS28240 2cf8dcbd3d4522be17a69f03c15dfcb3 951 Pfam PF03176 MMPL family 644 929 6.0E-72 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 BWK49_RS28240 2cf8dcbd3d4522be17a69f03c15dfcb3 951 SUPERFAMILY SSF82866 146 345 4.84E-32 T 06-07-2017 BWK49_RS28240 2cf8dcbd3d4522be17a69f03c15dfcb3 951 TIGRFAM TIGR00833 actII: transport protein 14 926 3.7E-287 T 06-07-2017 IPR004707 Membrane transport protein MmpL family GO:0016021 BWK49_RS28240 2cf8dcbd3d4522be17a69f03c15dfcb3 951 Gene3D G3DSA:1.20.1640.10 721 927 2.3E-23 T 06-07-2017 BWK49_RS28240 2cf8dcbd3d4522be17a69f03c15dfcb3 951 Gene3D G3DSA:1.20.1640.10 145 353 1.8E-33 T 06-07-2017 BWK49_RS01070 4a0770a139fe2015d8c3ba95c86fb548 189 Gene3D G3DSA:3.40.50.150 20 174 2.1E-22 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS01070 4a0770a139fe2015d8c3ba95c86fb548 189 SUPERFAMILY SSF53335 25 175 5.63E-26 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS01070 4a0770a139fe2015d8c3ba95c86fb548 189 Pfam PF08241 Methyltransferase domain 40 133 1.4E-14 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 BWK49_RS20135 89f25730be08f523b7afc4daf918e029 312 SUPERFAMILY SSF69593 252 301 8.11E-15 T 06-07-2017 BWK49_RS20135 89f25730be08f523b7afc4daf918e029 312 SUPERFAMILY SSF69593 64 212 8.11E-15 T 06-07-2017 BWK49_RS20135 89f25730be08f523b7afc4daf918e029 312 PIRSF PIRSF016753 14 312 3.9E-100 T 06-07-2017 IPR016676 Phospholipid/glycerol acyltransferase, predicted BWK49_RS20135 89f25730be08f523b7afc4daf918e029 312 SMART SM00563 89 209 1.2E-4 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 BWK49_RS20135 89f25730be08f523b7afc4daf918e029 312 Pfam PF01553 Acyltransferase 75 205 5.7E-11 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 BWK49_RS09090 636d8c7bb432d8adb46cc95715c318be 880 PIRSF PIRSF000460 1 823 2.7E-266 T 06-07-2017 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 BWK49_RS09090 636d8c7bb432d8adb46cc95715c318be 880 Pfam PF00343 Carbohydrate phosphorylase 251 643 1.9E-20 T 06-07-2017 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 BWK49_RS09090 636d8c7bb432d8adb46cc95715c318be 880 Pfam PF00343 Carbohydrate phosphorylase 128 173 1.6E-5 T 06-07-2017 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 BWK49_RS09090 636d8c7bb432d8adb46cc95715c318be 880 Gene3D G3DSA:3.40.50.2000 443 735 3.6E-85 T 06-07-2017 BWK49_RS09090 636d8c7bb432d8adb46cc95715c318be 880 Pfam PF11897 Protein of unknown function (DUF3417) 13 123 7.6E-37 T 06-07-2017 IPR024517 Glycogen phosphorylase, domain of unknown function DUF3417 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 BWK49_RS09090 636d8c7bb432d8adb46cc95715c318be 880 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 621 633 - T 06-07-2017 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 BWK49_RS09090 636d8c7bb432d8adb46cc95715c318be 880 Gene3D G3DSA:3.40.50.2000 25 442 2.1E-98 T 06-07-2017 BWK49_RS09090 636d8c7bb432d8adb46cc95715c318be 880 TIGRFAM TIGR02094 more_P_ylases: alpha-glucan phosphorylases 110 732 4.4E-228 T 06-07-2017 IPR011834 Alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 BWK49_RS09090 636d8c7bb432d8adb46cc95715c318be 880 SUPERFAMILY SSF53756 4 766 2.16E-201 T 06-07-2017 BWK49_RS05405 2d5372d91d5af3fdea1e06f7e9f0789c 411 ProSitePatterns PS01007 Transposases, Mutator family, signature. 233 257 - T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 BWK49_RS05405 2d5372d91d5af3fdea1e06f7e9f0789c 411 Pfam PF00872 Transposase, Mutator family 7 379 2.3E-147 T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 BWK49_RS04230 2d5372d91d5af3fdea1e06f7e9f0789c 411 ProSitePatterns PS01007 Transposases, Mutator family, signature. 233 257 - T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 BWK49_RS04230 2d5372d91d5af3fdea1e06f7e9f0789c 411 Pfam PF00872 Transposase, Mutator family 7 379 2.3E-147 T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 BWK49_RS09290 2b85824b596ef864cae747f5cdd44e8e 274 SUPERFAMILY SSF52096 8 270 5.91E-77 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS09290 2b85824b596ef864cae747f5cdd44e8e 274 Pfam PF00378 Enoyl-CoA hydratase/isomerase 19 269 1.2E-51 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 BWK49_RS09290 2b85824b596ef864cae747f5cdd44e8e 274 Gene3D G3DSA:3.90.226.10 9 269 3.0E-74 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS01400 0eb5e36a19e9d7e6d40ad9b47f3c25dc 113 Gene3D G3DSA:1.10.260.40 4 57 6.7E-5 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 BWK49_RS01400 0eb5e36a19e9d7e6d40ad9b47f3c25dc 113 Pfam PF09722 Protein of unknown function (DUF2384) 70 110 3.2E-7 T 06-07-2017 IPR024467 Domain of unknown function DUF2384 BWK49_RS01400 0eb5e36a19e9d7e6d40ad9b47f3c25dc 113 ProDom PD030784 PRECURSOR SIGNAL TRANSCRIPTIONAL PROBABLE RV1990C/MT2044 REGULATORY MB3210 MB2012C 18 112 4.0E-49 T 06-07-2017 BWK49_RS01190 bd70e8ec272822d07c08e588d1729fca 219 Pfam PF13545 Crp-like helix-turn-helix domain 123 196 1.1E-14 T 06-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 BWK49_RS01190 bd70e8ec272822d07c08e588d1729fca 219 SUPERFAMILY SSF51206 2 116 5.76E-31 T 06-07-2017 IPR018490 Cyclic nucleotide-binding-like BWK49_RS01190 bd70e8ec272822d07c08e588d1729fca 219 Gene3D G3DSA:1.10.10.10 120 199 1.5E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS01190 bd70e8ec272822d07c08e588d1729fca 219 Gene3D G3DSA:2.60.120.10 1 116 7.4E-30 T 06-07-2017 IPR014710 RmlC-like jelly roll fold BWK49_RS01190 bd70e8ec272822d07c08e588d1729fca 219 SMART SM00419 142 190 4.2E-9 T 06-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 BWK49_RS01190 bd70e8ec272822d07c08e588d1729fca 219 Pfam PF00027 Cyclic nucleotide-binding domain 5 90 1.8E-22 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain BWK49_RS01190 bd70e8ec272822d07c08e588d1729fca 219 PRINTS PR00103 cAMP-dependent protein kinase signature 6 20 8.3E-9 T 06-07-2017 BWK49_RS01190 bd70e8ec272822d07c08e588d1729fca 219 PRINTS PR00103 cAMP-dependent protein kinase signature 51 60 8.3E-9 T 06-07-2017 BWK49_RS01190 bd70e8ec272822d07c08e588d1729fca 219 PRINTS PR00103 cAMP-dependent protein kinase signature 21 35 8.3E-9 T 06-07-2017 BWK49_RS01190 bd70e8ec272822d07c08e588d1729fca 219 PRINTS PR00103 cAMP-dependent protein kinase signature 63 74 8.3E-9 T 06-07-2017 BWK49_RS01190 bd70e8ec272822d07c08e588d1729fca 219 SMART SM00100 1 103 7.8E-11 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain BWK49_RS01190 bd70e8ec272822d07c08e588d1729fca 219 SUPERFAMILY SSF46785 120 200 7.49E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS24655 4fd94bd8ce49ab935229053fc11ad056 795 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 471 488 - T 06-07-2017 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 BWK49_RS24655 4fd94bd8ce49ab935229053fc11ad056 795 Gene3D G3DSA:3.40.50.740 97 169 2.4E-68 T 06-07-2017 BWK49_RS24655 4fd94bd8ce49ab935229053fc11ad056 795 Gene3D G3DSA:3.40.50.740 353 379 2.4E-68 T 06-07-2017 BWK49_RS24655 4fd94bd8ce49ab935229053fc11ad056 795 Gene3D G3DSA:3.40.50.740 412 585 2.4E-68 T 06-07-2017 BWK49_RS24655 4fd94bd8ce49ab935229053fc11ad056 795 Gene3D G3DSA:2.40.40.20 586 769 3.1E-44 T 06-07-2017 BWK49_RS24655 4fd94bd8ce49ab935229053fc11ad056 795 Gene3D G3DSA:2.20.25.90 53 92 5.5E-5 T 06-07-2017 BWK49_RS24655 4fd94bd8ce49ab935229053fc11ad056 795 Gene3D G3DSA:3.40.228.10 171 352 3.2E-53 T 06-07-2017 BWK49_RS24655 4fd94bd8ce49ab935229053fc11ad056 795 SUPERFAMILY SSF53706 41 597 1.83E-158 T 06-07-2017 BWK49_RS24655 4fd94bd8ce49ab935229053fc11ad056 795 Pfam PF01568 Molydopterin dinucleotide binding domain 650 763 2.5E-27 T 06-07-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 BWK49_RS24655 4fd94bd8ce49ab935229053fc11ad056 795 Pfam PF00384 Molybdopterin oxidoreductase 97 521 4.4E-68 T 06-07-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS24655 4fd94bd8ce49ab935229053fc11ad056 795 SUPERFAMILY SSF50692 625 769 2.49E-37 T 06-07-2017 IPR009010 Aspartate decarboxylase-like domain BWK49_RS06055 778cca226d6839b86e2ac1d3d3582100 277 SUPERFAMILY SSF47203 125 265 2.42E-28 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS06055 778cca226d6839b86e2ac1d3d3582100 277 Gene3D G3DSA:1.20.140.10 129 266 2.3E-25 T 06-07-2017 BWK49_RS06055 778cca226d6839b86e2ac1d3d3582100 277 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 138 252 5.6E-18 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS13350 6eeacd5e9673cdb22866331ba04208b7 284 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 2 182 1.1E-49 T 06-07-2017 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 BWK49_RS13350 6eeacd5e9673cdb22866331ba04208b7 284 Gene3D G3DSA:3.30.70.120 212 283 3.4E-26 T 06-07-2017 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal BWK49_RS13350 6eeacd5e9673cdb22866331ba04208b7 284 TIGRFAM TIGR03455 HisG_C-term: ATP phosphoribosyltransferase, C-terminal domain 192 283 2.6E-27 T 06-07-2017 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 BWK49_RS13350 6eeacd5e9673cdb22866331ba04208b7 284 Gene3D G3DSA:3.40.190.10 1 140 1.2E-38 T 06-07-2017 BWK49_RS13350 6eeacd5e9673cdb22866331ba04208b7 284 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 141 162 - T 06-07-2017 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 BWK49_RS13350 6eeacd5e9673cdb22866331ba04208b7 284 Pfam PF01634 ATP phosphoribosyltransferase 49 205 2.2E-39 T 06-07-2017 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 BWK49_RS13350 6eeacd5e9673cdb22866331ba04208b7 284 SUPERFAMILY SSF53850 1 208 7.39E-62 T 06-07-2017 BWK49_RS13350 6eeacd5e9673cdb22866331ba04208b7 284 SUPERFAMILY SSF54913 212 283 2.0E-20 T 06-07-2017 IPR011322 Nitrogen regulatory PII-like, alpha/beta BWK49_RS13350 6eeacd5e9673cdb22866331ba04208b7 284 Pfam PF08029 HisG, C-terminal domain 210 279 1.7E-23 T 06-07-2017 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 BWK49_RS13350 6eeacd5e9673cdb22866331ba04208b7 284 Hamap MF_00079 ATP phosphoribosyltransferase [hisG]. 1 284 32.21 T 06-07-2017 IPR020621 ATP phosphoribosyltransferase HisG, long form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 BWK49_RS06805 94b6cf115005d53f3d1fa3d4b44de5c1 404 SUPERFAMILY SSF140459 1 167 9.94E-65 T 06-07-2017 BWK49_RS06805 94b6cf115005d53f3d1fa3d4b44de5c1 404 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 304 373 1.6E-8 T 06-07-2017 IPR022171 PPE family, C-terminal BWK49_RS06805 94b6cf115005d53f3d1fa3d4b44de5c1 404 Pfam PF00823 PPE family 1 156 5.8E-64 T 06-07-2017 IPR000030 PPE family BWK49_RS20545 79431ad5911298d777dab7c6d4008da8 562 SUPERFAMILY SSF81342 15 294 3.14E-59 T 06-07-2017 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 BWK49_RS20545 79431ad5911298d777dab7c6d4008da8 562 Gene3D G3DSA:1.20.810.10 16 435 1.0E-81 T 06-07-2017 IPR027387 Cytochrome b/b6-like domain Reactome: R-HSA-611105 BWK49_RS20545 79431ad5911298d777dab7c6d4008da8 562 Pfam PF13631 Cytochrome b(N-terminal)/b6/petB 115 289 2.3E-61 T 06-07-2017 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 BWK49_RS19695 5cb66c7d102c30c79cc78d9a223c8863 249 Pfam PF01738 Dienelactone hydrolase family 19 245 1.5E-54 T 06-07-2017 IPR002925 Dienelactone hydrolase GO:0016787 BWK49_RS19695 5cb66c7d102c30c79cc78d9a223c8863 249 SUPERFAMILY SSF53474 7 244 2.63E-43 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS19695 5cb66c7d102c30c79cc78d9a223c8863 249 Gene3D G3DSA:3.40.50.1820 8 244 1.3E-52 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS14825 6563e58c6e5d7e4ecf5ff2c8edcb5178 311 SUPERFAMILY SSF53850 100 302 2.02E-38 T 06-07-2017 BWK49_RS14825 6563e58c6e5d7e4ecf5ff2c8edcb5178 311 Pfam PF03466 LysR substrate binding domain 99 297 1.1E-44 T 06-07-2017 IPR005119 LysR, substrate-binding BWK49_RS14825 6563e58c6e5d7e4ecf5ff2c8edcb5178 311 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 13 68 6.7E-19 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 BWK49_RS14825 6563e58c6e5d7e4ecf5ff2c8edcb5178 311 Gene3D G3DSA:3.40.190.10 100 183 2.0E-18 T 06-07-2017 BWK49_RS14825 6563e58c6e5d7e4ecf5ff2c8edcb5178 311 SUPERFAMILY SSF46785 4 118 5.76E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS14825 6563e58c6e5d7e4ecf5ff2c8edcb5178 311 Gene3D G3DSA:3.40.190.10 184 275 1.9E-29 T 06-07-2017 BWK49_RS14825 6563e58c6e5d7e4ecf5ff2c8edcb5178 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 36 46 1.5E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 BWK49_RS14825 6563e58c6e5d7e4ecf5ff2c8edcb5178 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 46 57 1.5E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 BWK49_RS14825 6563e58c6e5d7e4ecf5ff2c8edcb5178 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 25 36 1.5E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 BWK49_RS14825 6563e58c6e5d7e4ecf5ff2c8edcb5178 311 Gene3D G3DSA:1.10.10.10 10 91 8.7E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS21980 a88c313ea0111b3618c9c99cdeb2971d 186 SMART SM00867 20 182 1.5E-35 T 06-07-2017 IPR007372 Lipid/polyisoprenoid-binding, YceI-like BWK49_RS21980 a88c313ea0111b3618c9c99cdeb2971d 186 Pfam PF04264 YceI-like domain 21 174 3.6E-30 T 06-07-2017 IPR007372 Lipid/polyisoprenoid-binding, YceI-like BWK49_RS21980 a88c313ea0111b3618c9c99cdeb2971d 186 SUPERFAMILY SSF101874 18 183 2.49E-33 T 06-07-2017 IPR007372 Lipid/polyisoprenoid-binding, YceI-like BWK49_RS21980 a88c313ea0111b3618c9c99cdeb2971d 186 Gene3D G3DSA:2.40.128.110 21 184 5.5E-36 T 06-07-2017 IPR007372 Lipid/polyisoprenoid-binding, YceI-like BWK49_RS02925 9f1d1b423e04e67a77fa368ef1e5b910 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 66 2.6E-31 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 BWK49_RS02925 9f1d1b423e04e67a77fa368ef1e5b910 67 SMART SM00357 3 67 2.3E-29 T 06-07-2017 IPR011129 Cold shock protein GO:0003676 BWK49_RS02925 9f1d1b423e04e67a77fa368ef1e5b910 67 PIRSF PIRSF002599 1 67 1.2E-24 T 06-07-2017 IPR012156 Cold shock, CspA GO:0003676 BWK49_RS02925 9f1d1b423e04e67a77fa368ef1e5b910 67 SUPERFAMILY SSF50249 1 66 5.57E-25 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS02925 9f1d1b423e04e67a77fa368ef1e5b910 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 06-07-2017 IPR019844 Cold-shock conserved site BWK49_RS02925 9f1d1b423e04e67a77fa368ef1e5b910 67 Gene3D G3DSA:2.40.50.140 1 65 7.9E-32 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS02925 9f1d1b423e04e67a77fa368ef1e5b910 67 PRINTS PR00050 Cold shock protein signature 40 58 5.2E-16 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 BWK49_RS02925 9f1d1b423e04e67a77fa368ef1e5b910 67 PRINTS PR00050 Cold shock protein signature 4 19 5.2E-16 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 BWK49_RS02925 9f1d1b423e04e67a77fa368ef1e5b910 67 PRINTS PR00050 Cold shock protein signature 25 34 5.2E-16 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 BWK49_RS18515 2c2d54e9b1c67ff73a14e3c3f2fa4e0c 249 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 BWK49_RS18515 2c2d54e9b1c67ff73a14e3c3f2fa4e0c 249 SUPERFAMILY SSF52540 10 240 4.28E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS18515 2c2d54e9b1c67ff73a14e3c3f2fa4e0c 249 Gene3D G3DSA:3.40.50.300 6 212 2.5E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS18515 2c2d54e9b1c67ff73a14e3c3f2fa4e0c 249 SMART SM00382 34 214 1.4E-18 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS18515 2c2d54e9b1c67ff73a14e3c3f2fa4e0c 249 Pfam PF00005 ABC transporter 26 164 6.6E-28 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 BWK49_RS09080 192d21fd686ed70d3bcf02f3de5095c0 731 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 633 730 8.5E-22 T 06-07-2017 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 BWK49_RS09080 192d21fd686ed70d3bcf02f3de5095c0 731 SUPERFAMILY SSF51445 190 621 3.7E-113 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily BWK49_RS09080 192d21fd686ed70d3bcf02f3de5095c0 731 TIGRFAM TIGR01515 branching_enzym: 1,4-alpha-glucan branching enzyme 114 728 2.8E-267 T 06-07-2017 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 BWK49_RS09080 192d21fd686ed70d3bcf02f3de5095c0 731 SUPERFAMILY SSF81296 23 119 5.95E-18 T 06-07-2017 IPR014756 Immunoglobulin E-set BWK49_RS09080 192d21fd686ed70d3bcf02f3de5095c0 731 Gene3D G3DSA:3.20.20.80 249 616 1.1E-92 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 BWK49_RS09080 192d21fd686ed70d3bcf02f3de5095c0 731 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 130 216 1.8E-20 T 06-07-2017 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 BWK49_RS09080 192d21fd686ed70d3bcf02f3de5095c0 731 Gene3D G3DSA:2.60.40.10 22 111 4.5E-13 T 06-07-2017 IPR013783 Immunoglobulin-like fold BWK49_RS09080 192d21fd686ed70d3bcf02f3de5095c0 731 Gene3D G3DSA:2.60.40.10 118 230 4.1E-35 T 06-07-2017 IPR013783 Immunoglobulin-like fold BWK49_RS09080 192d21fd686ed70d3bcf02f3de5095c0 731 SMART SM00642 259 611 8.3E-9 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 BWK49_RS09080 192d21fd686ed70d3bcf02f3de5095c0 731 Pfam PF00128 Alpha amylase, catalytic domain 280 349 1.6E-8 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 BWK49_RS09080 192d21fd686ed70d3bcf02f3de5095c0 731 Hamap MF_00685 1,4-alpha-glucan branching enzyme GlgB [glgB]. 106 731 43.517 T 06-07-2017 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 BWK49_RS09080 192d21fd686ed70d3bcf02f3de5095c0 731 Gene3D G3DSA:2.60.40.1180 628 730 1.6E-39 T 06-07-2017 IPR013780 Glycosyl hydrolase, all-beta BWK49_RS09080 192d21fd686ed70d3bcf02f3de5095c0 731 PIRSF PIRSF000463 15 731 2.2E-280 T 06-07-2017 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 BWK49_RS09080 192d21fd686ed70d3bcf02f3de5095c0 731 SUPERFAMILY SSF81296 147 214 8.4E-11 T 06-07-2017 IPR014756 Immunoglobulin E-set BWK49_RS09080 192d21fd686ed70d3bcf02f3de5095c0 731 SUPERFAMILY SSF51011 628 731 1.73E-34 T 06-07-2017 BWK49_RS14600 d6d13eefe3b35bc56dcc1f9103d4b606 130 Gene3D G3DSA:3.30.429.10 5 125 3.1E-28 T 06-07-2017 BWK49_RS14600 d6d13eefe3b35bc56dcc1f9103d4b606 130 Pfam PF14552 Tautomerase enzyme 38 118 2.5E-24 T 06-07-2017 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 BWK49_RS14600 d6d13eefe3b35bc56dcc1f9103d4b606 130 SUPERFAMILY SSF55331 2 128 2.23E-35 T 06-07-2017 IPR014347 Tautomerase/MIF superfamily BWK49_RS24165 61a01c48430b39b15b125adf872f4b49 326 Gene3D G3DSA:3.40.50.720 4 122 7.3E-22 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS24165 61a01c48430b39b15b125adf872f4b49 326 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 115 288 4.0E-50 T 06-07-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 BWK49_RS24165 61a01c48430b39b15b125adf872f4b49 326 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 42 320 7.0E-14 T 06-07-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 BWK49_RS24165 61a01c48430b39b15b125adf872f4b49 326 SUPERFAMILY SSF52283 4 136 5.32E-19 T 06-07-2017 BWK49_RS24165 61a01c48430b39b15b125adf872f4b49 326 Gene3D G3DSA:3.40.50.720 123 291 8.8E-54 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS24165 61a01c48430b39b15b125adf872f4b49 326 SUPERFAMILY SSF51735 106 289 1.58E-47 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS24165 61a01c48430b39b15b125adf872f4b49 326 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 198 220 - T 06-07-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site BWK49_RS12595 46eeee8fd8646a4c2720d8683dea58d2 400 Pfam PF01494 FAD binding domain 4 333 4.6E-51 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 BWK49_RS12595 46eeee8fd8646a4c2720d8683dea58d2 400 SUPERFAMILY SSF51905 264 355 1.19E-55 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS12595 46eeee8fd8646a4c2720d8683dea58d2 400 SUPERFAMILY SSF51905 4 174 1.19E-55 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS12595 46eeee8fd8646a4c2720d8683dea58d2 400 Gene3D G3DSA:3.50.50.60 265 341 1.6E-45 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS12595 46eeee8fd8646a4c2720d8683dea58d2 400 Gene3D G3DSA:3.50.50.60 3 179 1.6E-45 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS12595 46eeee8fd8646a4c2720d8683dea58d2 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 2.2E-22 T 06-07-2017 BWK49_RS12595 46eeee8fd8646a4c2720d8683dea58d2 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 277 292 2.2E-22 T 06-07-2017 BWK49_RS12595 46eeee8fd8646a4c2720d8683dea58d2 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 153 168 2.2E-22 T 06-07-2017 BWK49_RS12595 46eeee8fd8646a4c2720d8683dea58d2 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 292 308 2.2E-22 T 06-07-2017 BWK49_RS05995 97d47a692d209b3c5c2f06bf6c6804d8 414 PRINTS PR00385 P450 superfamily signature 286 297 7.8E-8 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS05995 97d47a692d209b3c5c2f06bf6c6804d8 414 PRINTS PR00385 P450 superfamily signature 354 363 7.8E-8 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS05995 97d47a692d209b3c5c2f06bf6c6804d8 414 PRINTS PR00385 P450 superfamily signature 363 374 7.8E-8 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS05995 97d47a692d209b3c5c2f06bf6c6804d8 414 PRINTS PR00385 P450 superfamily signature 249 266 7.8E-8 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS05995 97d47a692d209b3c5c2f06bf6c6804d8 414 Gene3D G3DSA:1.10.630.10 23 414 1.3E-108 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS05995 97d47a692d209b3c5c2f06bf6c6804d8 414 SUPERFAMILY SSF48264 26 414 6.42E-84 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS05995 97d47a692d209b3c5c2f06bf6c6804d8 414 Pfam PF00067 Cytochrome P450 199 383 2.1E-20 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS05995 97d47a692d209b3c5c2f06bf6c6804d8 414 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 356 365 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 BWK49_RS05995 97d47a692d209b3c5c2f06bf6c6804d8 414 PRINTS PR00359 B-class P450 signature 204 226 6.7E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS05995 97d47a692d209b3c5c2f06bf6c6804d8 414 PRINTS PR00359 B-class P450 signature 363 374 6.7E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS05995 97d47a692d209b3c5c2f06bf6c6804d8 414 PRINTS PR00359 B-class P450 signature 150 166 6.7E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS05995 97d47a692d209b3c5c2f06bf6c6804d8 414 PRINTS PR00359 B-class P450 signature 103 114 6.7E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS05995 97d47a692d209b3c5c2f06bf6c6804d8 414 PRINTS PR00359 B-class P450 signature 286 297 6.7E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS05995 97d47a692d209b3c5c2f06bf6c6804d8 414 PRINTS PR00359 B-class P450 signature 304 331 6.7E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS05995 97d47a692d209b3c5c2f06bf6c6804d8 414 PRINTS PR00359 B-class P450 signature 167 182 6.7E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS05995 97d47a692d209b3c5c2f06bf6c6804d8 414 PRINTS PR00359 B-class P450 signature 354 363 6.7E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS05995 97d47a692d209b3c5c2f06bf6c6804d8 414 PRINTS PR00359 B-class P450 signature 332 347 6.7E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS08385 0fc62b1d261d9590f00b05a01d5ff4b7 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 1.2E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS08385 0fc62b1d261d9590f00b05a01d5ff4b7 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 1.2E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS08385 0fc62b1d261d9590f00b05a01d5ff4b7 203 SUPERFAMILY SSF46689 4 86 2.34E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS08385 0fc62b1d261d9590f00b05a01d5ff4b7 203 Gene3D G3DSA:1.10.357.10 3 199 2.7E-29 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS08385 0fc62b1d261d9590f00b05a01d5ff4b7 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 61 2.2E-13 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS18475 f8ab960ba4c6c2b30a557bef4c848a80 378 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 5 370 2.7E-130 T 06-07-2017 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 BWK49_RS18475 f8ab960ba4c6c2b30a557bef4c848a80 378 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 253 269 6.3E-32 T 06-07-2017 BWK49_RS18475 f8ab960ba4c6c2b30a557bef4c848a80 378 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 183 197 6.3E-32 T 06-07-2017 BWK49_RS18475 f8ab960ba4c6c2b30a557bef4c848a80 378 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 222 236 6.3E-32 T 06-07-2017 BWK49_RS18475 f8ab960ba4c6c2b30a557bef4c848a80 378 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 270 287 6.3E-32 T 06-07-2017 BWK49_RS18475 f8ab960ba4c6c2b30a557bef4c848a80 378 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 295 306 6.3E-32 T 06-07-2017 BWK49_RS18475 f8ab960ba4c6c2b30a557bef4c848a80 378 Pfam PF00117 Glutamine amidotransferase class-I 187 367 3.9E-35 T 06-07-2017 IPR017926 Glutamine amidotransferase BWK49_RS18475 f8ab960ba4c6c2b30a557bef4c848a80 378 PRINTS PR00096 Glutamine amidotransferase superfamily signature 344 357 2.3E-11 T 06-07-2017 BWK49_RS18475 f8ab960ba4c6c2b30a557bef4c848a80 378 PRINTS PR00096 Glutamine amidotransferase superfamily signature 253 264 2.3E-11 T 06-07-2017 BWK49_RS18475 f8ab960ba4c6c2b30a557bef4c848a80 378 PRINTS PR00096 Glutamine amidotransferase superfamily signature 225 234 2.3E-11 T 06-07-2017 BWK49_RS18475 f8ab960ba4c6c2b30a557bef4c848a80 378 SMART SM01097 3 135 2.9E-78 T 06-07-2017 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 BWK49_RS18475 f8ab960ba4c6c2b30a557bef4c848a80 378 SUPERFAMILY SSF52317 155 370 1.35E-48 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like BWK49_RS18475 f8ab960ba4c6c2b30a557bef4c848a80 378 PRINTS PR00097 Anthranilate synthase component II signature 344 357 6.0E-6 T 06-07-2017 BWK49_RS18475 f8ab960ba4c6c2b30a557bef4c848a80 378 PRINTS PR00097 Anthranilate synthase component II signature 253 264 6.0E-6 T 06-07-2017 BWK49_RS18475 f8ab960ba4c6c2b30a557bef4c848a80 378 PRINTS PR00097 Anthranilate synthase component II signature 225 234 6.0E-6 T 06-07-2017 BWK49_RS18475 f8ab960ba4c6c2b30a557bef4c848a80 378 Gene3D G3DSA:3.50.30.20 4 140 3.6E-53 T 06-07-2017 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 BWK49_RS18475 f8ab960ba4c6c2b30a557bef4c848a80 378 Gene3D G3DSA:3.40.50.880 158 370 1.1E-58 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like BWK49_RS18475 f8ab960ba4c6c2b30a557bef4c848a80 378 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 4 133 3.5E-48 T 06-07-2017 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 BWK49_RS18475 f8ab960ba4c6c2b30a557bef4c848a80 378 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 3 373 43.361 T 06-07-2017 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 BWK49_RS18475 f8ab960ba4c6c2b30a557bef4c848a80 378 SUPERFAMILY SSF52021 4 138 1.96E-50 T 06-07-2017 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 BWK49_RS09835 eab7f67b6566415129c8a3933728cc79 223 PIRSF PIRSF012637 4 223 1.3E-85 T 06-07-2017 IPR016601 Uncharacterised conserved protein UCP012637 BWK49_RS20750 90bb6b7d1e3b004738aaa77412229f00 362 Gene3D G3DSA:3.40.50.1820 71 360 3.6E-90 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS20750 90bb6b7d1e3b004738aaa77412229f00 362 SUPERFAMILY SSF53474 89 358 7.33E-67 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS20750 90bb6b7d1e3b004738aaa77412229f00 362 Pfam PF07859 alpha/beta hydrolase fold 128 335 1.3E-74 T 06-07-2017 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 BWK49_RS01770 0329ff16797af1256b31752427203e47 420 SUPERFAMILY SSF48557 12 377 1.54E-58 T 06-07-2017 IPR008948 L-Aspartase-like GO:0003824 BWK49_RS01770 0329ff16797af1256b31752427203e47 420 Pfam PF00206 Lyase 85 296 9.2E-23 T 06-07-2017 IPR022761 Fumarate lyase, N-terminal BWK49_RS01770 0329ff16797af1256b31752427203e47 420 Gene3D G3DSA:1.10.275.10 10 95 1.9E-11 T 06-07-2017 IPR024083 Fumarase/histidase, N-terminal BWK49_RS01770 0329ff16797af1256b31752427203e47 420 Gene3D G3DSA:1.20.200.10 96 373 5.1E-65 T 06-07-2017 BWK49_RS01770 0329ff16797af1256b31752427203e47 420 PRINTS PR00149 Fumarate lyase superfamily signature 93 111 3.7E-6 T 06-07-2017 IPR000362 Fumarate lyase family BWK49_RS01770 0329ff16797af1256b31752427203e47 420 PRINTS PR00149 Fumarate lyase superfamily signature 138 156 3.7E-6 T 06-07-2017 IPR000362 Fumarate lyase family BWK49_RS05175 9a9c3b9ac99fb090b45b8cb3045d6f28 209 Gene3D G3DSA:1.10.357.10 13 203 5.2E-23 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS05175 9a9c3b9ac99fb090b45b8cb3045d6f28 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 2.8E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS05175 9a9c3b9ac99fb090b45b8cb3045d6f28 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 2.8E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS05175 9a9c3b9ac99fb090b45b8cb3045d6f28 209 SUPERFAMILY SSF46689 12 84 4.04E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS05175 9a9c3b9ac99fb090b45b8cb3045d6f28 209 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 63 4.9E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS16380 e0461582d25a57aef464994e08cdf9dc 241 SMART SM00862 160 235 2.5E-19 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 BWK49_RS16380 e0461582d25a57aef464994e08cdf9dc 241 Pfam PF00072 Response regulator receiver domain 14 123 1.0E-29 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 BWK49_RS16380 e0461582d25a57aef464994e08cdf9dc 241 SUPERFAMILY SSF52172 10 132 2.99E-42 T 06-07-2017 IPR011006 CheY-like superfamily BWK49_RS16380 e0461582d25a57aef464994e08cdf9dc 241 Gene3D G3DSA:1.10.10.10 160 236 9.5E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS16380 e0461582d25a57aef464994e08cdf9dc 241 SMART SM00448 12 122 5.6E-45 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 BWK49_RS16380 e0461582d25a57aef464994e08cdf9dc 241 Gene3D G3DSA:3.40.50.2300 12 159 8.3E-44 T 06-07-2017 BWK49_RS16380 e0461582d25a57aef464994e08cdf9dc 241 Pfam PF00486 Transcriptional regulatory protein, C terminal 163 235 4.0E-20 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 BWK49_RS16380 e0461582d25a57aef464994e08cdf9dc 241 SUPERFAMILY SSF46894 144 236 1.12E-24 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 BWK49_RS17180 9ff13b2822f7cebb816724b531a1900a 908 SMART SM00474 321 497 1.0E-22 T 06-07-2017 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 BWK49_RS17180 9ff13b2822f7cebb816724b531a1900a 908 Gene3D G3DSA:1.20.1060.10 523 641 2.2E-31 T 06-07-2017 BWK49_RS17180 9ff13b2822f7cebb816724b531a1900a 908 ProSitePatterns PS00447 DNA polymerase family A signature. 733 752 - T 06-07-2017 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 BWK49_RS17180 9ff13b2822f7cebb816724b531a1900a 908 SMART SM00279 192 227 2.7E-14 T 06-07-2017 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 BWK49_RS17180 9ff13b2822f7cebb816724b531a1900a 908 TIGRFAM TIGR00593 pola: DNA polymerase I 22 906 0.0 T 06-07-2017 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 BWK49_RS17180 9ff13b2822f7cebb816724b531a1900a 908 Pfam PF00476 DNA polymerase family A 531 904 4.5E-143 T 06-07-2017 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 BWK49_RS17180 9ff13b2822f7cebb816724b531a1900a 908 SUPERFAMILY SSF56672 504 905 6.12E-140 T 06-07-2017 BWK49_RS17180 9ff13b2822f7cebb816724b531a1900a 908 Gene3D G3DSA:1.10.150.20 691 797 1.3E-30 T 06-07-2017 BWK49_RS17180 9ff13b2822f7cebb816724b531a1900a 908 SUPERFAMILY SSF88723 15 189 5.89E-55 T 06-07-2017 IPR029060 PIN domain-like BWK49_RS17180 9ff13b2822f7cebb816724b531a1900a 908 Gene3D G3DSA:3.40.50.1010 21 204 2.0E-68 T 06-07-2017 IPR029060 PIN domain-like BWK49_RS17180 9ff13b2822f7cebb816724b531a1900a 908 Gene3D G3DSA:3.30.70.370 642 690 1.6E-64 T 06-07-2017 BWK49_RS17180 9ff13b2822f7cebb816724b531a1900a 908 Gene3D G3DSA:3.30.70.370 798 906 1.6E-64 T 06-07-2017 BWK49_RS17180 9ff13b2822f7cebb816724b531a1900a 908 Gene3D G3DSA:3.30.420.10 325 520 7.1E-52 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS17180 9ff13b2822f7cebb816724b531a1900a 908 SMART SM00482 664 871 6.5E-116 T 06-07-2017 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 BWK49_RS17180 9ff13b2822f7cebb816724b531a1900a 908 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 22 189 2.5E-54 T 06-07-2017 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 BWK49_RS17180 9ff13b2822f7cebb816724b531a1900a 908 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 191 284 5.5E-26 T 06-07-2017 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 BWK49_RS17180 9ff13b2822f7cebb816724b531a1900a 908 SMART SM00475 18 280 1.9E-142 T 06-07-2017 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 BWK49_RS17180 9ff13b2822f7cebb816724b531a1900a 908 SUPERFAMILY SSF47807 190 303 3.74E-30 T 06-07-2017 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 BWK49_RS17180 9ff13b2822f7cebb816724b531a1900a 908 SUPERFAMILY SSF53098 326 497 1.52E-31 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS17180 9ff13b2822f7cebb816724b531a1900a 908 PRINTS PR00868 DNA-polymerase family A (pol I) signature 770 781 9.8E-76 T 06-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 BWK49_RS17180 9ff13b2822f7cebb816724b531a1900a 908 PRINTS PR00868 DNA-polymerase family A (pol I) signature 679 702 9.8E-76 T 06-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 BWK49_RS17180 9ff13b2822f7cebb816724b531a1900a 908 PRINTS PR00868 DNA-polymerase family A (pol I) signature 656 671 9.8E-76 T 06-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 BWK49_RS17180 9ff13b2822f7cebb816724b531a1900a 908 PRINTS PR00868 DNA-polymerase family A (pol I) signature 792 803 9.8E-76 T 06-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 BWK49_RS17180 9ff13b2822f7cebb816724b531a1900a 908 PRINTS PR00868 DNA-polymerase family A (pol I) signature 824 840 9.8E-76 T 06-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 BWK49_RS17180 9ff13b2822f7cebb816724b531a1900a 908 PRINTS PR00868 DNA-polymerase family A (pol I) signature 633 655 9.8E-76 T 06-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 BWK49_RS17180 9ff13b2822f7cebb816724b531a1900a 908 PRINTS PR00868 DNA-polymerase family A (pol I) signature 733 758 9.8E-76 T 06-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 BWK49_RS17180 9ff13b2822f7cebb816724b531a1900a 908 PRINTS PR00868 DNA-polymerase family A (pol I) signature 709 722 9.8E-76 T 06-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 BWK49_RS17180 9ff13b2822f7cebb816724b531a1900a 908 PRINTS PR00868 DNA-polymerase family A (pol I) signature 854 867 9.8E-76 T 06-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 BWK49_RS17180 9ff13b2822f7cebb816724b531a1900a 908 Gene3D G3DSA:1.10.150.20 205 264 2.2E-23 T 06-07-2017 BWK49_RS20685 d628c0f91d2d6b8143a8c0fa1c619262 341 SUPERFAMILY SSF53686 1 305 1.15E-69 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme BWK49_RS20685 d628c0f91d2d6b8143a8c0fa1c619262 341 Gene3D G3DSA:3.40.50.1100 33 138 1.9E-26 T 06-07-2017 BWK49_RS20685 d628c0f91d2d6b8143a8c0fa1c619262 341 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 1 283 3.7E-52 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme BWK49_RS20685 d628c0f91d2d6b8143a8c0fa1c619262 341 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 23 41 - T 06-07-2017 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 BWK49_RS20685 d628c0f91d2d6b8143a8c0fa1c619262 341 Gene3D G3DSA:3.40.50.1100 1 32 1.1E-36 T 06-07-2017 BWK49_RS20685 d628c0f91d2d6b8143a8c0fa1c619262 341 Gene3D G3DSA:3.40.50.1100 144 302 1.1E-36 T 06-07-2017 BWK49_RS02870 1ee20e9f4a2579e25bd20ce48aad05ce 285 Gene3D G3DSA:3.40.50.1000 99 248 7.7E-49 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS02870 1ee20e9f4a2579e25bd20ce48aad05ce 285 SUPERFAMILY SSF56784 25 242 8.27E-30 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS02870 1ee20e9f4a2579e25bd20ce48aad05ce 285 Pfam PF12710 haloacid dehalogenase-like hydrolase 28 213 1.1E-34 T 06-07-2017 BWK49_RS02870 1ee20e9f4a2579e25bd20ce48aad05ce 285 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 27 215 3.2E-25 T 06-07-2017 IPR006383 HAD-superfamily hydrolase, subfamily IB, PSPase-like GO:0008152|GO:0016791 BWK49_RS02870 1ee20e9f4a2579e25bd20ce48aad05ce 285 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 27 226 2.9E-72 T 06-07-2017 IPR006385 HAD-superfamily hydrolase, subfamily IB, PSPase-like, bacterial BWK49_RS07585 0f4fb6a44b87dee780276ee6fdeea190 94 PIRSF PIRSF037656 1 94 7.4E-57 T 06-07-2017 IPR009416 Protein of unknown function DUF1066 BWK49_RS07585 0f4fb6a44b87dee780276ee6fdeea190 94 SUPERFAMILY SSF140453 2 93 1.24E-17 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like BWK49_RS07585 0f4fb6a44b87dee780276ee6fdeea190 94 Gene3D G3DSA:1.10.287.1060 2 94 5.5E-14 T 06-07-2017 BWK49_RS07585 0f4fb6a44b87dee780276ee6fdeea190 94 Pfam PF06013 Proteins of 100 residues with WXG 3 87 3.5E-15 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like BWK49_RS18110 a01d6364352aa992b1751f407958c2bd 182 SUPERFAMILY SSF55068 3 161 6.28E-66 T 06-07-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 BWK49_RS18110 a01d6364352aa992b1751f407958c2bd 182 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 5 152 9.6E-52 T 06-07-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 BWK49_RS18110 a01d6364352aa992b1751f407958c2bd 182 Gene3D G3DSA:3.30.1060.10 3 153 1.1E-66 T 06-07-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 BWK49_RS18110 a01d6364352aa992b1751f407958c2bd 182 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 3 158 34.093 T 06-07-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 BWK49_RS18110 a01d6364352aa992b1751f407958c2bd 182 Pfam PF01625 Peptide methionine sulfoxide reductase 6 152 2.6E-58 T 06-07-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 BWK49_RS14655 da82edb72f1b66640915c0d83274a4dd 431 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 287 426 1.9E-47 T 06-07-2017 IPR008136 CinA, C-terminal BWK49_RS14655 da82edb72f1b66640915c0d83274a4dd 431 Gene3D G3DSA:3.90.950.20 270 427 2.8E-55 T 06-07-2017 IPR008136 CinA, C-terminal BWK49_RS14655 da82edb72f1b66640915c0d83274a4dd 431 Gene3D G3DSA:3.40.980.10 6 225 1.6E-40 T 06-07-2017 IPR001453 MoaB/Mog domain BWK49_RS14655 da82edb72f1b66640915c0d83274a4dd 431 TIGRFAM TIGR00200 cinA_nterm: competence/damage-inducible protein CinA N-terminal domain 6 427 2.0E-79 T 06-07-2017 IPR008135 Competence-induced protein CinA BWK49_RS14655 da82edb72f1b66640915c0d83274a4dd 431 PIRSF PIRSF006728 4 430 3.1E-126 T 06-07-2017 IPR008135 Competence-induced protein CinA BWK49_RS14655 da82edb72f1b66640915c0d83274a4dd 431 SUPERFAMILY SSF142433 279 427 8.24E-53 T 06-07-2017 IPR008136 CinA, C-terminal BWK49_RS14655 da82edb72f1b66640915c0d83274a4dd 431 SUPERFAMILY SSF53218 6 104 2.22E-37 T 06-07-2017 IPR001453 MoaB/Mog domain BWK49_RS14655 da82edb72f1b66640915c0d83274a4dd 431 SUPERFAMILY SSF53218 131 224 2.22E-37 T 06-07-2017 IPR001453 MoaB/Mog domain BWK49_RS14655 da82edb72f1b66640915c0d83274a4dd 431 Hamap MF_00226_B Putative competence-damage inducible protein [cinA]. 1 431 141.887 T 06-07-2017 IPR008135 Competence-induced protein CinA BWK49_RS14655 da82edb72f1b66640915c0d83274a4dd 431 Pfam PF00994 Probable molybdopterin binding domain 8 183 9.8E-37 T 06-07-2017 IPR001453 MoaB/Mog domain BWK49_RS14655 da82edb72f1b66640915c0d83274a4dd 431 SMART SM00852 8 189 4.2E-40 T 06-07-2017 IPR001453 MoaB/Mog domain BWK49_RS14655 da82edb72f1b66640915c0d83274a4dd 431 Pfam PF02464 Competence-damaged protein 281 427 2.3E-56 T 06-07-2017 IPR008136 CinA, C-terminal BWK49_RS03570 67fca0e7ddca1d0b40619616b8114c15 503 Gene3D G3DSA:3.40.50.980 20 160 3.9E-18 T 06-07-2017 BWK49_RS03570 67fca0e7ddca1d0b40619616b8114c15 503 Pfam PF13193 AMP-binding enzyme C-terminal domain 405 481 3.0E-10 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS03570 67fca0e7ddca1d0b40619616b8114c15 503 SUPERFAMILY SSF56801 23 494 1.02E-101 T 06-07-2017 BWK49_RS03570 67fca0e7ddca1d0b40619616b8114c15 503 Gene3D G3DSA:2.30.38.10 315 385 3.9E-18 T 06-07-2017 BWK49_RS03570 67fca0e7ddca1d0b40619616b8114c15 503 Gene3D G3DSA:3.30.300.30 395 490 1.5E-19 T 06-07-2017 BWK49_RS03570 67fca0e7ddca1d0b40619616b8114c15 503 Gene3D G3DSA:3.40.50.980 161 314 9.6E-23 T 06-07-2017 BWK49_RS03570 67fca0e7ddca1d0b40619616b8114c15 503 Pfam PF00501 AMP-binding enzyme 25 395 7.8E-62 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS03570 67fca0e7ddca1d0b40619616b8114c15 503 ProSitePatterns PS00455 Putative AMP-binding domain signature. 155 166 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS17430 34fac6403daebe92ca184a710157b461 385 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 236 245 - T 06-07-2017 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 BWK49_RS17430 34fac6403daebe92ca184a710157b461 385 Gene3D G3DSA:3.40.640.10 59 272 1.9E-73 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 BWK49_RS17430 34fac6403daebe92ca184a710157b461 385 SUPERFAMILY SSF53383 32 382 7.26E-86 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase BWK49_RS17430 34fac6403daebe92ca184a710157b461 385 Pfam PF00155 Aminotransferase class I and II 43 374 1.4E-55 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 BWK49_RS17430 34fac6403daebe92ca184a710157b461 385 Gene3D G3DSA:3.90.1150.10 273 379 1.5E-12 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 BWK49_RS08050 2f96a071adee4b7983830645abe1566e 280 SUPERFAMILY SSF51735 11 258 3.97E-39 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS08050 2f96a071adee4b7983830645abe1566e 280 Pfam PF00106 short chain dehydrogenase 12 127 1.2E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS08050 2f96a071adee4b7983830645abe1566e 280 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 158 256 2.9E-17 T 06-07-2017 BWK49_RS08050 2f96a071adee4b7983830645abe1566e 280 Gene3D G3DSA:3.40.50.720 11 258 7.5E-38 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS08050 2f96a071adee4b7983830645abe1566e 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 239 2.4E-18 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS08050 2f96a071adee4b7983830645abe1566e 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 73 84 2.4E-18 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS08050 2f96a071adee4b7983830645abe1566e 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 2.4E-18 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS08050 2f96a071adee4b7983830645abe1566e 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 110 126 2.4E-18 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS08050 2f96a071adee4b7983830645abe1566e 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 182 2.4E-18 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS08050 2f96a071adee4b7983830645abe1566e 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 184 201 2.4E-18 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS22360 a2018a58243561c9e577ce377526f366 1082 Pfam PF07993 Male sterility protein 713 949 5.7E-58 T 06-07-2017 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 BWK49_RS22360 a2018a58243561c9e577ce377526f366 1082 ProSitePatterns PS00012 Phosphopantetheine attachment site. 608 623 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site BWK49_RS22360 a2018a58243561c9e577ce377526f366 1082 Gene3D G3DSA:3.40.50.980 179 336 2.3E-30 T 06-07-2017 BWK49_RS22360 a2018a58243561c9e577ce377526f366 1082 Gene3D G3DSA:3.40.50.980 2 178 4.5E-29 T 06-07-2017 BWK49_RS22360 a2018a58243561c9e577ce377526f366 1082 Gene3D G3DSA:3.40.50.720 711 1044 3.3E-41 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS22360 a2018a58243561c9e577ce377526f366 1082 TIGRFAM TIGR01746 Thioester-redct: thioester reductase domain 711 1055 6.5E-73 T 06-07-2017 IPR010080 Thioester reductase-like domain BWK49_RS22360 a2018a58243561c9e577ce377526f366 1082 SUPERFAMILY SSF51735 711 996 4.45E-40 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS22360 a2018a58243561c9e577ce377526f366 1082 Gene3D G3DSA:3.30.300.30 451 553 2.6E-17 T 06-07-2017 BWK49_RS22360 a2018a58243561c9e577ce377526f366 1082 Pfam PF00501 AMP-binding enzyme 15 460 2.5E-81 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS22360 a2018a58243561c9e577ce377526f366 1082 SUPERFAMILY SSF56801 3 560 1.96E-108 T 06-07-2017 BWK49_RS22360 a2018a58243561c9e577ce377526f366 1082 Gene3D G3DSA:2.30.38.10 369 449 4.3E-18 T 06-07-2017 BWK49_RS11920 a0c36839dddac7388177d165928932fd 296 Pfam PF04536 Acid phosphatase of thylakoid lumen protein 36 154 1.4E-14 T 06-07-2017 IPR007621 TPM domain BWK49_RS16410 34c2b6f61bdab0f8abe1d9cd3bed6e27 1515 Pfam PF00668 Condensation domain 9 299 7.5E-53 T 06-07-2017 IPR001242 Condensation domain BWK49_RS16410 34c2b6f61bdab0f8abe1d9cd3bed6e27 1515 Pfam PF00668 Condensation domain 1073 1358 1.0E-28 T 06-07-2017 IPR001242 Condensation domain BWK49_RS16410 34c2b6f61bdab0f8abe1d9cd3bed6e27 1515 Gene3D G3DSA:1.10.1200.10 963 1039 1.4E-16 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS16410 34c2b6f61bdab0f8abe1d9cd3bed6e27 1515 SUPERFAMILY SSF52777 1059 1253 1.03E-23 T 06-07-2017 BWK49_RS16410 34c2b6f61bdab0f8abe1d9cd3bed6e27 1515 Pfam PF13193 AMP-binding enzyme C-terminal domain 869 943 4.6E-11 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS16410 34c2b6f61bdab0f8abe1d9cd3bed6e27 1515 Pfam PF00550 Phosphopantetheine attachment site 976 1037 1.4E-10 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS16410 34c2b6f61bdab0f8abe1d9cd3bed6e27 1515 SMART SM00823 Phosphopantetheine attachment site 973 1041 7.4E-4 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS16410 34c2b6f61bdab0f8abe1d9cd3bed6e27 1515 Gene3D G3DSA:3.40.50.980 457 610 8.7E-42 T 06-07-2017 BWK49_RS16410 34c2b6f61bdab0f8abe1d9cd3bed6e27 1515 SUPERFAMILY SSF52777 1240 1510 8.56E-20 T 06-07-2017 BWK49_RS16410 34c2b6f61bdab0f8abe1d9cd3bed6e27 1515 Gene3D G3DSA:3.40.50.980 611 771 7.0E-27 T 06-07-2017 BWK49_RS16410 34c2b6f61bdab0f8abe1d9cd3bed6e27 1515 SUPERFAMILY SSF47336 969 1037 3.93E-11 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS16410 34c2b6f61bdab0f8abe1d9cd3bed6e27 1515 Gene3D G3DSA:2.30.38.10 772 850 2.4E-22 T 06-07-2017 BWK49_RS16410 34c2b6f61bdab0f8abe1d9cd3bed6e27 1515 Pfam PF00501 AMP-binding enzyme 462 861 2.5E-78 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS16410 34c2b6f61bdab0f8abe1d9cd3bed6e27 1515 ProSitePatterns PS00455 Putative AMP-binding domain signature. 606 617 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS16410 34c2b6f61bdab0f8abe1d9cd3bed6e27 1515 Gene3D G3DSA:3.30.300.30 855 955 5.8E-29 T 06-07-2017 BWK49_RS16410 34c2b6f61bdab0f8abe1d9cd3bed6e27 1515 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 484 885 2.7E-109 T 06-07-2017 IPR010071 Amino acid adenylation domain BWK49_RS16410 34c2b6f61bdab0f8abe1d9cd3bed6e27 1515 SUPERFAMILY SSF56801 448 983 1.96E-126 T 06-07-2017 BWK49_RS16410 34c2b6f61bdab0f8abe1d9cd3bed6e27 1515 SUPERFAMILY SSF52777 185 422 5.11E-42 T 06-07-2017 BWK49_RS16410 34c2b6f61bdab0f8abe1d9cd3bed6e27 1515 SUPERFAMILY SSF52777 6 200 4.78E-37 T 06-07-2017 BWK49_RS10785 40f9b44ae043a6027c7a365fb015e1bb 426 Pfam PF04909 Amidohydrolase 71 373 8.3E-31 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 BWK49_RS10785 40f9b44ae043a6027c7a365fb015e1bb 426 Gene3D G3DSA:3.20.20.140 9 390 1.1E-70 T 06-07-2017 BWK49_RS10785 40f9b44ae043a6027c7a365fb015e1bb 426 SUPERFAMILY SSF51556 67 381 3.08E-75 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS10785 40f9b44ae043a6027c7a365fb015e1bb 426 SUPERFAMILY SSF51556 9 36 3.08E-75 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS20865 047aacf7981b958759d446007e640d5c 198 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 180 2.7E-50 T 06-07-2017 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 BWK49_RS20865 047aacf7981b958759d446007e640d5c 198 Gene3D G3DSA:3.20.19.10 1 184 1.3E-32 T 06-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel BWK49_RS20865 047aacf7981b958759d446007e640d5c 198 SUPERFAMILY SSF52016 1 187 2.94E-48 T 06-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel BWK49_RS20865 047aacf7981b958759d446007e640d5c 198 Pfam PF00694 Aconitase C-terminal domain 1 116 3.8E-22 T 06-07-2017 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 BWK49_RS20865 047aacf7981b958759d446007e640d5c 198 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 191 37.166 T 06-07-2017 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 BWK49_RS27040 79c66482b92e66fe37ae6f829133142d 608 PIRSF PIRSF001348 1 608 4.2E-295 T 06-07-2017 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 BWK49_RS27040 79c66482b92e66fe37ae6f829133142d 608 Gene3D G3DSA:3.90.228.20 245 314 1.5E-31 T 06-07-2017 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 BWK49_RS27040 79c66482b92e66fe37ae6f829133142d 608 Gene3D G3DSA:3.90.228.20 337 606 2.3E-100 T 06-07-2017 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 BWK49_RS27040 79c66482b92e66fe37ae6f829133142d 608 ProSitePatterns PS00505 Phosphoenolpyruvate carboxykinase (GTP) signature. 269 277 - T 06-07-2017 IPR018091 Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site GO:0004613 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 BWK49_RS27040 79c66482b92e66fe37ae6f829133142d 608 SUPERFAMILY SSF68923 12 244 3.24E-97 T 06-07-2017 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 BWK49_RS27040 79c66482b92e66fe37ae6f829133142d 608 Gene3D G3DSA:3.40.449.10 11 244 1.3E-94 T 06-07-2017 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 BWK49_RS27040 79c66482b92e66fe37ae6f829133142d 608 Pfam PF00821 Phosphoenolpyruvate carboxykinase 21 604 6.5E-283 T 06-07-2017 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 BWK49_RS27040 79c66482b92e66fe37ae6f829133142d 608 SUPERFAMILY SSF53795 245 605 5.95E-158 T 06-07-2017 BWK49_RS27040 79c66482b92e66fe37ae6f829133142d 608 Hamap MF_00452 Phosphoenolpyruvate carboxykinase [GTP] [pckG]. 10 605 51.506 T 06-07-2017 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 BWK49_RS07100 4af28161c41dad7d88a54c5f8e21a040 152 Gene3D G3DSA:1.20.5.220 108 125 6.9E-11 T 06-07-2017 IPR029027 Single alpha-helix domain Reactome: R-HSA-611105 BWK49_RS07100 4af28161c41dad7d88a54c5f8e21a040 152 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 1 123 1.7E-21 T 06-07-2017 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 BWK49_RS07100 4af28161c41dad7d88a54c5f8e21a040 152 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 78 86 3.7E-6 T 06-07-2017 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 BWK49_RS07100 4af28161c41dad7d88a54c5f8e21a040 152 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 4 18 3.7E-6 T 06-07-2017 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 BWK49_RS07100 4af28161c41dad7d88a54c5f8e21a040 152 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 88 97 3.7E-6 T 06-07-2017 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 BWK49_RS07100 4af28161c41dad7d88a54c5f8e21a040 152 SUPERFAMILY SSF81330 11 118 6.67E-26 T 06-07-2017 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 BWK49_RS07100 4af28161c41dad7d88a54c5f8e21a040 152 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 1 121 1.8E-32 T 06-07-2017 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 BWK49_RS06855 db2107b367c484f78eec79e36398de31 263 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 147 175 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS06855 db2107b367c484f78eec79e36398de31 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 1.2E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS06855 db2107b367c484f78eec79e36398de31 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 1.2E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS06855 db2107b367c484f78eec79e36398de31 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 1.2E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS06855 db2107b367c484f78eec79e36398de31 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 1.2E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS06855 db2107b367c484f78eec79e36398de31 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 1.2E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS06855 db2107b367c484f78eec79e36398de31 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 1.2E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS06855 db2107b367c484f78eec79e36398de31 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 86 97 1.2E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS06855 db2107b367c484f78eec79e36398de31 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 148 1.2E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS06855 db2107b367c484f78eec79e36398de31 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 1.2E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS06855 db2107b367c484f78eec79e36398de31 263 Gene3D G3DSA:3.40.50.720 4 253 1.5E-81 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS06855 db2107b367c484f78eec79e36398de31 263 SUPERFAMILY SSF51735 9 253 8.7E-79 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS06855 db2107b367c484f78eec79e36398de31 263 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 252 2.7E-60 T 06-07-2017 BWK49_RS20330 4161b5852f38b37adbf30d7b8106afa5 360 Gene3D G3DSA:2.30.40.10 10 55 0.001 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 BWK49_RS20330 4161b5852f38b37adbf30d7b8106afa5 360 Gene3D G3DSA:2.30.40.10 319 358 3.4E-5 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 BWK49_RS20330 4161b5852f38b37adbf30d7b8106afa5 360 Gene3D G3DSA:3.20.20.140 56 318 2.0E-64 T 06-07-2017 BWK49_RS20330 4161b5852f38b37adbf30d7b8106afa5 360 SUPERFAMILY SSF51556 45 321 1.91E-62 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS20330 4161b5852f38b37adbf30d7b8106afa5 360 Pfam PF01979 Amidohydrolase family 42 354 4.8E-16 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 BWK49_RS23040 0b69fcb0cb45af16ce142be5949601de 299 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 4 288 4.4E-95 T 06-07-2017 IPR005913 dTDP-4-dehydrorhamnose reductase family Reactome: R-HSA-156581 BWK49_RS23040 0b69fcb0cb45af16ce142be5949601de 299 Pfam PF04321 RmlD substrate binding domain 4 289 2.0E-98 T 06-07-2017 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581 BWK49_RS23040 0b69fcb0cb45af16ce142be5949601de 299 Gene3D G3DSA:3.40.50.720 4 237 1.5E-49 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS23040 0b69fcb0cb45af16ce142be5949601de 299 SUPERFAMILY SSF51735 4 286 1.06E-78 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS07835 5166cff978f530fce763437036e129c0 252 Pfam PF14030 Protein of unknown function (DUF4245) 52 242 5.0E-53 T 06-07-2017 IPR025339 Protein of unknown function DUF4245 BWK49_RS06230 3c249a6e5288cf525208df610cf82b42 297 Gene3D G3DSA:1.10.1040.10 162 292 3.6E-38 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 BWK49_RS06230 3c249a6e5288cf525208df610cf82b42 297 PIRSF PIRSF000103 1 293 2.9E-64 T 06-07-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 BWK49_RS06230 3c249a6e5288cf525208df610cf82b42 297 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 155 1.9E-35 T 06-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 BWK49_RS06230 3c249a6e5288cf525208df610cf82b42 297 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 163 284 6.7E-38 T 06-07-2017 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 BWK49_RS06230 3c249a6e5288cf525208df610cf82b42 297 Gene3D G3DSA:3.40.50.720 1 155 7.9E-41 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS06230 3c249a6e5288cf525208df610cf82b42 297 SUPERFAMILY SSF51735 1 158 5.19E-34 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS06230 3c249a6e5288cf525208df610cf82b42 297 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 5 18 - T 06-07-2017 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 BWK49_RS06230 3c249a6e5288cf525208df610cf82b42 297 SUPERFAMILY SSF48179 162 291 9.41E-33 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 BWK49_RS20230 0b08ee00069ba994a7b3adfe105fdb9c 389 SUPERFAMILY SSF102405 105 299 2.29E-33 T 06-07-2017 BWK49_RS20230 0b08ee00069ba994a7b3adfe105fdb9c 389 Gene3D G3DSA:3.40.50.450 127 271 2.7E-14 T 06-07-2017 BWK49_RS20230 0b08ee00069ba994a7b3adfe105fdb9c 389 Pfam PF02481 DNA recombination-mediator protein A 74 290 4.3E-69 T 06-07-2017 IPR003488 DNA recombination-mediator protein A GO:0009294 BWK49_RS20230 0b08ee00069ba994a7b3adfe105fdb9c 389 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 71 297 2.4E-77 T 06-07-2017 IPR003488 DNA recombination-mediator protein A GO:0009294 BWK49_RS20230 0b08ee00069ba994a7b3adfe105fdb9c 389 Gene3D G3DSA:1.10.10.10 318 382 3.8E-7 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS23905 291e56f95e3d77403c2156b64d69aed1 279 Pfam PF01738 Dienelactone hydrolase family 31 189 8.5E-6 T 06-07-2017 IPR002925 Dienelactone hydrolase GO:0016787 BWK49_RS23905 291e56f95e3d77403c2156b64d69aed1 279 SUPERFAMILY SSF53474 14 205 1.86E-20 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS23905 291e56f95e3d77403c2156b64d69aed1 279 Gene3D G3DSA:3.40.50.1820 29 200 1.6E-17 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS12810 9ee9f109d86aae9fa58db4eec0137a9e 515 Gene3D G3DSA:3.40.220.10 27 185 1.8E-24 T 06-07-2017 BWK49_RS12810 9ee9f109d86aae9fa58db4eec0137a9e 515 PRINTS PR00481 Cytosol aminopeptidase signature 274 291 2.6E-47 T 06-07-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 BWK49_RS12810 9ee9f109d86aae9fa58db4eec0137a9e 515 PRINTS PR00481 Cytosol aminopeptidase signature 355 375 2.6E-47 T 06-07-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 BWK49_RS12810 9ee9f109d86aae9fa58db4eec0137a9e 515 PRINTS PR00481 Cytosol aminopeptidase signature 296 317 2.6E-47 T 06-07-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 BWK49_RS12810 9ee9f109d86aae9fa58db4eec0137a9e 515 PRINTS PR00481 Cytosol aminopeptidase signature 333 354 2.6E-47 T 06-07-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 BWK49_RS12810 9ee9f109d86aae9fa58db4eec0137a9e 515 PRINTS PR00481 Cytosol aminopeptidase signature 383 398 2.6E-47 T 06-07-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 BWK49_RS12810 9ee9f109d86aae9fa58db4eec0137a9e 515 SUPERFAMILY SSF53187 188 511 7.53E-106 T 06-07-2017 BWK49_RS12810 9ee9f109d86aae9fa58db4eec0137a9e 515 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 193 504 1.1E-109 T 06-07-2017 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 BWK49_RS12810 9ee9f109d86aae9fa58db4eec0137a9e 515 SUPERFAMILY SSF52949 27 179 3.71E-22 T 06-07-2017 BWK49_RS12810 9ee9f109d86aae9fa58db4eec0137a9e 515 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 30 157 1.1E-24 T 06-07-2017 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 BWK49_RS12810 9ee9f109d86aae9fa58db4eec0137a9e 515 Gene3D G3DSA:3.40.630.10 186 513 2.7E-127 T 06-07-2017 BWK49_RS12810 9ee9f109d86aae9fa58db4eec0137a9e 515 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 13 513 34.758 T 06-07-2017 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 BWK49_RS12810 9ee9f109d86aae9fa58db4eec0137a9e 515 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 359 366 - T 06-07-2017 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 BWK49_RS17625 4e608ef1675b83a9ad30475ac09ce274 963 TIGRFAM TIGR00833 actII: transport protein 22 933 0.0 T 06-07-2017 IPR004707 Membrane transport protein MmpL family GO:0016021 BWK49_RS17625 4e608ef1675b83a9ad30475ac09ce274 963 Pfam PF03176 MMPL family 606 941 2.2E-106 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 BWK49_RS17625 4e608ef1675b83a9ad30475ac09ce274 963 Pfam PF03176 MMPL family 56 384 2.7E-116 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 BWK49_RS17625 4e608ef1675b83a9ad30475ac09ce274 963 Gene3D G3DSA:1.20.1640.10 730 934 1.1E-24 T 06-07-2017 BWK49_RS17625 4e608ef1675b83a9ad30475ac09ce274 963 Gene3D G3DSA:1.20.1640.10 156 356 2.7E-29 T 06-07-2017 BWK49_RS17625 4e608ef1675b83a9ad30475ac09ce274 963 SUPERFAMILY SSF82866 156 351 7.46E-28 T 06-07-2017 BWK49_RS17625 4e608ef1675b83a9ad30475ac09ce274 963 SUPERFAMILY SSF82866 724 933 1.57E-30 T 06-07-2017 BWK49_RS02675 fe8ccd4fdb4e494c3e3ca414808399a4 738 SUPERFAMILY SSF81606 410 605 1.26E-6 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 BWK49_RS02675 fe8ccd4fdb4e494c3e3ca414808399a4 738 Gene3D G3DSA:3.30.450.20 105 218 1.3E-16 T 06-07-2017 BWK49_RS02675 fe8ccd4fdb4e494c3e3ca414808399a4 738 Pfam PF13426 PAS domain 120 219 4.6E-7 T 06-07-2017 IPR000014 PAS domain BWK49_RS02675 fe8ccd4fdb4e494c3e3ca414808399a4 738 Pfam PF13581 Histidine kinase-like ATPase domain 618 729 3.0E-18 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS02675 fe8ccd4fdb4e494c3e3ca414808399a4 738 Gene3D G3DSA:1.10.1240.30 1 83 4.0E-18 T 06-07-2017 IPR017944 KaiA/RbsU helical domain GO:0006468 BWK49_RS02675 fe8ccd4fdb4e494c3e3ca414808399a4 738 SUPERFAMILY SSF55874 642 733 1.13E-6 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS02675 fe8ccd4fdb4e494c3e3ca414808399a4 738 SMART SM00331 391 607 1.1E-25 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 BWK49_RS02675 fe8ccd4fdb4e494c3e3ca414808399a4 738 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 106 220 4.8E-12 T 06-07-2017 IPR000014 PAS domain BWK49_RS02675 fe8ccd4fdb4e494c3e3ca414808399a4 738 SUPERFAMILY SSF55785 96 218 2.62E-15 T 06-07-2017 IPR000014 PAS domain BWK49_RS02675 fe8ccd4fdb4e494c3e3ca414808399a4 738 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 421 607 8.8E-41 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 BWK49_RS02675 fe8ccd4fdb4e494c3e3ca414808399a4 738 Pfam PF08673 Phosphoserine phosphatase RsbU, N-terminal domain 10 83 2.3E-16 T 06-07-2017 IPR014787 Phosphoserine phosphatase RsbU, N-terminal KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3 BWK49_RS18625 0c6e10e8901153bafa5243f8e6c0a56d 133 SUPERFAMILY SSF111038 2 129 1.57E-32 T 06-07-2017 IPR001602 Uncharacterised protein family UPF0047 BWK49_RS18625 0c6e10e8901153bafa5243f8e6c0a56d 133 Pfam PF01894 Uncharacterised protein family UPF0047 17 128 7.0E-26 T 06-07-2017 IPR001602 Uncharacterised protein family UPF0047 BWK49_RS18625 0c6e10e8901153bafa5243f8e6c0a56d 133 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 10 127 1.1E-21 T 06-07-2017 IPR001602 Uncharacterised protein family UPF0047 BWK49_RS18625 0c6e10e8901153bafa5243f8e6c0a56d 133 Gene3D G3DSA:2.60.120.460 2 130 1.7E-32 T 06-07-2017 IPR001602 Uncharacterised protein family UPF0047 BWK49_RS18625 0c6e10e8901153bafa5243f8e6c0a56d 133 PIRSF PIRSF004681 1 133 1.9E-32 T 06-07-2017 IPR001602 Uncharacterised protein family UPF0047 BWK49_RS18625 0c6e10e8901153bafa5243f8e6c0a56d 133 ProSitePatterns PS01314 Uncharacterized protein family UPF0047 signature. 94 112 - T 06-07-2017 IPR001602 Uncharacterised protein family UPF0047 BWK49_RS27680 a039994c206d018fa44d5a2db7c1d373 272 PIRSF PIRSF006648 11 272 4.6E-59 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 BWK49_RS27680 a039994c206d018fa44d5a2db7c1d373 272 Pfam PF01061 ABC-2 type transporter 35 239 3.3E-37 T 06-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 BWK49_RS27680 a039994c206d018fa44d5a2db7c1d373 272 PRINTS PR00164 ABC-2 type transport system membrane protein signature 77 99 2.8E-11 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 BWK49_RS27680 a039994c206d018fa44d5a2db7c1d373 272 PRINTS PR00164 ABC-2 type transport system membrane protein signature 46 67 2.8E-11 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 BWK49_RS27680 a039994c206d018fa44d5a2db7c1d373 272 PRINTS PR00164 ABC-2 type transport system membrane protein signature 197 216 2.8E-11 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 BWK49_RS27680 a039994c206d018fa44d5a2db7c1d373 272 PRINTS PR00164 ABC-2 type transport system membrane protein signature 217 236 2.8E-11 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 BWK49_RS27680 a039994c206d018fa44d5a2db7c1d373 272 PRINTS PR00164 ABC-2 type transport system membrane protein signature 160 184 2.8E-11 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 BWK49_RS12255 b5fde9fd45576c2b461aaf688502a1c7 461 SUPERFAMILY SSF55103 218 457 1.13E-50 T 06-07-2017 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 BWK49_RS12255 b5fde9fd45576c2b461aaf688502a1c7 461 Gene3D G3DSA:3.30.465.10 96 214 9.4E-35 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 BWK49_RS12255 b5fde9fd45576c2b461aaf688502a1c7 461 SUPERFAMILY SSF56176 2 213 3.18E-60 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 BWK49_RS12255 b5fde9fd45576c2b461aaf688502a1c7 461 Pfam PF01565 FAD binding domain 40 178 2.2E-37 T 06-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 BWK49_RS12255 b5fde9fd45576c2b461aaf688502a1c7 461 Pfam PF02913 FAD linked oxidases, C-terminal domain 217 453 2.8E-53 T 06-07-2017 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 BWK49_RS12255 b5fde9fd45576c2b461aaf688502a1c7 461 Gene3D G3DSA:1.10.45.10 416 453 3.7E-9 T 06-07-2017 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 BWK49_RS12255 b5fde9fd45576c2b461aaf688502a1c7 461 Gene3D G3DSA:3.30.43.10 2 94 6.2E-22 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 BWK49_RS07675 2a92594290a0e767c6774f10f03c9fc5 172 Pfam PF05995 Cysteine dioxygenase type I 33 91 1.1E-11 T 06-07-2017 IPR010300 Cysteine dioxygenase type I GO:0005506|GO:0016702|GO:0055114 KEGG: 00270+1.13.11.20|KEGG: 00430+1.13.11.20|MetaCyc: PWY-5331|Reactome: R-HSA-1614558 BWK49_RS07675 2a92594290a0e767c6774f10f03c9fc5 172 SUPERFAMILY SSF51182 30 169 6.44E-26 T 06-07-2017 IPR011051 RmlC-like cupin domain BWK49_RS07675 2a92594290a0e767c6774f10f03c9fc5 172 Gene3D G3DSA:2.60.120.10 39 154 3.2E-12 T 06-07-2017 IPR014710 RmlC-like jelly roll fold BWK49_RS19200 071638babd37eb00e13e22677738869a 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 4.3E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS19200 071638babd37eb00e13e22677738869a 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 4.3E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS19200 071638babd37eb00e13e22677738869a 188 Gene3D G3DSA:1.10.357.10 12 166 5.3E-21 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS19200 071638babd37eb00e13e22677738869a 188 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 57 5.0E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS19200 071638babd37eb00e13e22677738869a 188 SUPERFAMILY SSF46689 8 65 4.54E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS09590 b3751c6b59c40a5c504e2f1d3c8a2425 270 Pfam PF13560 Helix-turn-helix domain 1 58 3.6E-10 T 06-07-2017 BWK49_RS09590 b3751c6b59c40a5c504e2f1d3c8a2425 270 SUPERFAMILY SSF47413 1 53 8.85E-12 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 BWK49_RS09590 b3751c6b59c40a5c504e2f1d3c8a2425 270 Gene3D G3DSA:1.10.260.40 1 52 1.2E-12 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 BWK49_RS09590 b3751c6b59c40a5c504e2f1d3c8a2425 270 SMART SM00530 1 55 4.9E-8 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 BWK49_RS03800 0c520c0759a28358675362be68471a23 408 SUPERFAMILY SSF48264 13 408 1.57E-88 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS03800 0c520c0759a28358675362be68471a23 408 PRINTS PR00359 B-class P450 signature 89 100 4.2E-39 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS03800 0c520c0759a28358675362be68471a23 408 PRINTS PR00359 B-class P450 signature 297 324 4.2E-39 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS03800 0c520c0759a28358675362be68471a23 408 PRINTS PR00359 B-class P450 signature 325 340 4.2E-39 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS03800 0c520c0759a28358675362be68471a23 408 PRINTS PR00359 B-class P450 signature 356 367 4.2E-39 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS03800 0c520c0759a28358675362be68471a23 408 PRINTS PR00359 B-class P450 signature 280 291 4.2E-39 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS03800 0c520c0759a28358675362be68471a23 408 PRINTS PR00359 B-class P450 signature 158 173 4.2E-39 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS03800 0c520c0759a28358675362be68471a23 408 PRINTS PR00359 B-class P450 signature 347 356 4.2E-39 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS03800 0c520c0759a28358675362be68471a23 408 PRINTS PR00359 B-class P450 signature 141 157 4.2E-39 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS03800 0c520c0759a28358675362be68471a23 408 PRINTS PR00359 B-class P450 signature 199 221 4.2E-39 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS03800 0c520c0759a28358675362be68471a23 408 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 349 358 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 BWK49_RS03800 0c520c0759a28358675362be68471a23 408 Gene3D G3DSA:1.10.630.10 12 406 9.1E-110 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS03800 0c520c0759a28358675362be68471a23 408 Pfam PF00067 Cytochrome P450 199 376 7.9E-20 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS05835 ae9d7b709e152b280298b7e8124e092e 360 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 113 3.8E-17 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS05835 ae9d7b709e152b280298b7e8124e092e 360 SUPERFAMILY SSF47203 225 360 4.76E-12 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS05835 ae9d7b709e152b280298b7e8124e092e 360 Gene3D G3DSA:1.10.540.10 2 115 2.3E-19 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS05835 ae9d7b709e152b280298b7e8124e092e 360 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 225 358 1.7E-7 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS05835 ae9d7b709e152b280298b7e8124e092e 360 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 118 212 4.7E-19 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 BWK49_RS05835 ae9d7b709e152b280298b7e8124e092e 360 Gene3D G3DSA:1.20.140.10 215 359 1.1E-15 T 06-07-2017 BWK49_RS05835 ae9d7b709e152b280298b7e8124e092e 360 Gene3D G3DSA:2.40.110.10 117 214 2.1E-33 T 06-07-2017 BWK49_RS05835 ae9d7b709e152b280298b7e8124e092e 360 SUPERFAMILY SSF56645 2 238 1.44E-65 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS06925 6ad07c4fb2dbd715758815e75152a503 382 SUPERFAMILY SSF51905 14 231 3.24E-19 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS06925 6ad07c4fb2dbd715758815e75152a503 382 Gene3D G3DSA:3.50.50.60 152 269 7.2E-6 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS06925 6ad07c4fb2dbd715758815e75152a503 382 Gene3D G3DSA:3.50.50.60 15 122 3.0E-15 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS06925 6ad07c4fb2dbd715758815e75152a503 382 Pfam PF16170 Domain of unknown function (DUF4873) 292 379 1.3E-28 T 06-07-2017 IPR032371 Domain of unknown function DUF4873 BWK49_RS14275 4043d06c681cfeb13c454bfd4da696d6 338 Pfam PF00107 Zinc-binding dehydrogenase 173 283 7.4E-22 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 BWK49_RS14275 4043d06c681cfeb13c454bfd4da696d6 338 Gene3D G3DSA:3.40.50.720 165 283 6.9E-34 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS14275 4043d06c681cfeb13c454bfd4da696d6 338 SUPERFAMILY SSF51735 142 305 2.06E-37 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS14275 4043d06c681cfeb13c454bfd4da696d6 338 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 58 72 - T 06-07-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 BWK49_RS14275 4043d06c681cfeb13c454bfd4da696d6 338 SMART SM00829 8 336 5.7E-5 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 BWK49_RS14275 4043d06c681cfeb13c454bfd4da696d6 338 SUPERFAMILY SSF50129 1 165 1.46E-43 T 06-07-2017 IPR011032 GroES-like BWK49_RS14275 4043d06c681cfeb13c454bfd4da696d6 338 Gene3D G3DSA:3.90.180.10 1 164 2.7E-36 T 06-07-2017 IPR011032 GroES-like BWK49_RS14275 4043d06c681cfeb13c454bfd4da696d6 338 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 120 2.3E-20 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 BWK49_RS27800 0b6cf1315ac0fb62128663bb142049fa 284 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 19 256 2.3E-55 T 06-07-2017 BWK49_RS27800 0b6cf1315ac0fb62128663bb142049fa 284 Gene3D G3DSA:3.40.50.720 8 256 1.6E-72 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS27800 0b6cf1315ac0fb62128663bb142049fa 284 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 89 100 1.4E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27800 0b6cf1315ac0fb62128663bb142049fa 284 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 187 204 1.4E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27800 0b6cf1315ac0fb62128663bb142049fa 284 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 156 1.4E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27800 0b6cf1315ac0fb62128663bb142049fa 284 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 220 240 1.4E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27800 0b6cf1315ac0fb62128663bb142049fa 284 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 185 1.4E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27800 0b6cf1315ac0fb62128663bb142049fa 284 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 15 32 1.4E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27800 0b6cf1315ac0fb62128663bb142049fa 284 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 153 181 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS27800 0b6cf1315ac0fb62128663bb142049fa 284 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 89 100 4.5E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27800 0b6cf1315ac0fb62128663bb142049fa 284 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 166 185 4.5E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27800 0b6cf1315ac0fb62128663bb142049fa 284 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 154 4.5E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27800 0b6cf1315ac0fb62128663bb142049fa 284 SUPERFAMILY SSF51735 11 256 8.28E-68 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS23435 4de99586fb38061a59cd7d385598d75e 584 SUPERFAMILY SSF51905 4 260 5.02E-71 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS23435 4de99586fb38061a59cd7d385598d75e 584 SUPERFAMILY SSF51905 359 431 5.02E-71 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS23435 4de99586fb38061a59cd7d385598d75e 584 Gene3D G3DSA:1.20.58.100 438 535 6.0E-38 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 BWK49_RS23435 4de99586fb38061a59cd7d385598d75e 584 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 8 584 4.6E-256 T 06-07-2017 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 BWK49_RS23435 4de99586fb38061a59cd7d385598d75e 584 PIRSF PIRSF000171 1 578 1.3E-45 T 06-07-2017 IPR030664 Succinate dehydrogenase/fumarate reductase, alpha/adenylylsulphate reductase subunit Reactome: R-HSA-611105|Reactome: R-HSA-71403 BWK49_RS23435 4de99586fb38061a59cd7d385598d75e 584 SUPERFAMILY SSF56425 237 355 1.94E-41 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 BWK49_RS23435 4de99586fb38061a59cd7d385598d75e 584 Pfam PF02910 Fumarate reductase flavoprotein C-term 455 584 2.0E-43 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 BWK49_RS23435 4de99586fb38061a59cd7d385598d75e 584 Gene3D G3DSA:3.50.50.60 3 243 1.0E-115 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS23435 4de99586fb38061a59cd7d385598d75e 584 Gene3D G3DSA:3.50.50.60 351 423 1.0E-115 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS23435 4de99586fb38061a59cd7d385598d75e 584 Gene3D G3DSA:4.10.80.40 536 581 2.2E-15 T 06-07-2017 BWK49_RS23435 4de99586fb38061a59cd7d385598d75e 584 TIGRFAM TIGR01816 sdhA_forward: succinate dehydrogenase, flavoprotein subunit 5 584 7.6E-303 T 06-07-2017 IPR011281 Succinate dehydrogenase, flavoprotein subunit GO:0006099|GO:0016627|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 BWK49_RS23435 4de99586fb38061a59cd7d385598d75e 584 SUPERFAMILY SSF46977 447 584 1.15E-47 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 BWK49_RS23435 4de99586fb38061a59cd7d385598d75e 584 Gene3D G3DSA:3.90.700.10 244 349 5.0E-39 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 BWK49_RS23435 4de99586fb38061a59cd7d385598d75e 584 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 41 50 - T 06-07-2017 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 BWK49_RS23435 4de99586fb38061a59cd7d385598d75e 584 Pfam PF00890 FAD binding domain 8 401 1.1E-110 T 06-07-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 BWK49_RS15710 07aa17e0c00e0877f103360565dd5090 152 SUPERFAMILY SSF54427 3 148 3.32E-29 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS15710 07aa17e0c00e0877f103360565dd5090 152 Pfam PF13577 SnoaL-like domain 5 137 6.3E-15 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain BWK49_RS15710 07aa17e0c00e0877f103360565dd5090 152 Gene3D G3DSA:3.10.450.50 3 150 1.8E-34 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS21830 153258524cd3f47d258c1afe2b71537a 229 SMART SM00382 28 215 2.5E-16 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS21830 153258524cd3f47d258c1afe2b71537a 229 TIGRFAM TIGR02673 FtsE: cell division ATP-binding protein FtsE 1 214 2.8E-87 T 06-07-2017 IPR005286 Cell division protein FtsE, ATP-binding GO:0005524|GO:0051301 BWK49_RS21830 153258524cd3f47d258c1afe2b71537a 229 SUPERFAMILY SSF52540 1 220 7.27E-68 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS21830 153258524cd3f47d258c1afe2b71537a 229 Pfam PF00005 ABC transporter 19 166 1.4E-34 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 BWK49_RS21830 153258524cd3f47d258c1afe2b71537a 229 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 BWK49_RS21830 153258524cd3f47d258c1afe2b71537a 229 Gene3D G3DSA:3.40.50.300 1 220 1.6E-70 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS21295 4a19ffdfcb7ded5f94f9e1a48be7d645 116 Pfam PF11829 Protein of unknown function (DUF3349) 1 89 3.8E-27 T 06-07-2017 IPR021784 Protein of unknown function DUF3349 BWK49_RS01575 b9f155a9b7b2e9aac94c4b4a7bff4ace 146 Pfam PF07883 Cupin domain 40 103 1.1E-13 T 06-07-2017 IPR013096 Cupin 2, conserved barrel BWK49_RS01575 b9f155a9b7b2e9aac94c4b4a7bff4ace 146 SUPERFAMILY SSF51182 10 109 6.82E-20 T 06-07-2017 IPR011051 RmlC-like cupin domain BWK49_RS01575 b9f155a9b7b2e9aac94c4b4a7bff4ace 146 Gene3D G3DSA:2.60.120.10 30 144 5.0E-21 T 06-07-2017 IPR014710 RmlC-like jelly roll fold BWK49_RS09920 aa5779d4a74152856075a399e531e300 211 Gene3D G3DSA:3.90.226.10 28 205 4.1E-72 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS09920 aa5779d4a74152856075a399e531e300 211 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 121 134 - T 06-07-2017 IPR033135 ClpP, histidine active site BWK49_RS09920 aa5779d4a74152856075a399e531e300 211 PRINTS PR00127 Clp protease catalytic subunit P signature 120 139 1.4E-41 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 BWK49_RS09920 aa5779d4a74152856075a399e531e300 211 PRINTS PR00127 Clp protease catalytic subunit P signature 28 43 1.4E-41 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 BWK49_RS09920 aa5779d4a74152856075a399e531e300 211 PRINTS PR00127 Clp protease catalytic subunit P signature 68 88 1.4E-41 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 BWK49_RS09920 aa5779d4a74152856075a399e531e300 211 PRINTS PR00127 Clp protease catalytic subunit P signature 99 116 1.4E-41 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 BWK49_RS09920 aa5779d4a74152856075a399e531e300 211 PRINTS PR00127 Clp protease catalytic subunit P signature 179 198 1.4E-41 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 BWK49_RS09920 aa5779d4a74152856075a399e531e300 211 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 99 110 - T 06-07-2017 IPR018215 ClpP, Ser active site BWK49_RS09920 aa5779d4a74152856075a399e531e300 211 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 12 204 38.391 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 BWK49_RS09920 aa5779d4a74152856075a399e531e300 211 Pfam PF00574 Clp protease 27 203 4.2E-74 T 06-07-2017 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA BWK49_RS09920 aa5779d4a74152856075a399e531e300 211 SUPERFAMILY SSF52096 21 205 1.53E-61 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS08890 54da116e6b5f757451631af67c638561 360 Gene3D G3DSA:3.40.50.1100 68 152 2.0E-41 T 06-07-2017 BWK49_RS08890 54da116e6b5f757451631af67c638561 360 Gene3D G3DSA:3.40.50.1100 153 338 7.0E-50 T 06-07-2017 BWK49_RS08890 54da116e6b5f757451631af67c638561 360 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 60 73 - T 06-07-2017 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 BWK49_RS08890 54da116e6b5f757451631af67c638561 360 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 32 327 4.1E-73 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme BWK49_RS08890 54da116e6b5f757451631af67c638561 360 TIGRFAM TIGR00260 thrC: threonine synthase 16 334 1.1E-94 T 06-07-2017 IPR004450 Threonine synthase-like BWK49_RS08890 54da116e6b5f757451631af67c638561 360 PIRSF PIRSF038945 1 359 1.8E-180 T 06-07-2017 IPR026260 Threonine synthase, bacterial/archaeal GO:0004795|GO:0009088 KEGG: 00260+4.2.3.1|KEGG: 00750+4.2.3.1 BWK49_RS08890 54da116e6b5f757451631af67c638561 360 SUPERFAMILY SSF53686 11 341 2.23E-103 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme BWK49_RS03105 4df6985f80bc77cf47e0084c0081570d 323 SUPERFAMILY SSF53098 138 313 3.29E-33 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS03105 4df6985f80bc77cf47e0084c0081570d 323 Pfam PF00665 Integrase core domain 136 272 8.6E-31 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 BWK49_RS03105 4df6985f80bc77cf47e0084c0081570d 323 Pfam PF13011 leucine-zipper of insertion element IS481 1 82 1.7E-17 T 06-07-2017 IPR024967 DNA-binding domain, IS481-type BWK49_RS03105 4df6985f80bc77cf47e0084c0081570d 323 Gene3D G3DSA:3.30.420.10 132 309 2.6E-41 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS03105 4df6985f80bc77cf47e0084c0081570d 323 SUPERFAMILY SSF46689 6 109 2.33E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS06225 4df6985f80bc77cf47e0084c0081570d 323 SUPERFAMILY SSF53098 138 313 3.29E-33 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS06225 4df6985f80bc77cf47e0084c0081570d 323 Pfam PF00665 Integrase core domain 136 272 8.6E-31 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 BWK49_RS06225 4df6985f80bc77cf47e0084c0081570d 323 Pfam PF13011 leucine-zipper of insertion element IS481 1 82 1.7E-17 T 06-07-2017 IPR024967 DNA-binding domain, IS481-type BWK49_RS06225 4df6985f80bc77cf47e0084c0081570d 323 Gene3D G3DSA:3.30.420.10 132 309 2.6E-41 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS06225 4df6985f80bc77cf47e0084c0081570d 323 SUPERFAMILY SSF46689 6 109 2.33E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS09485 dbeb2e1e3766aa1aaf7905726ae5f21e 402 SUPERFAMILY SSF51556 8 37 1.19E-68 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS09485 dbeb2e1e3766aa1aaf7905726ae5f21e 402 SUPERFAMILY SSF51556 91 390 1.19E-68 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS09485 dbeb2e1e3766aa1aaf7905726ae5f21e 402 Gene3D G3DSA:3.20.20.140 10 37 2.0E-64 T 06-07-2017 BWK49_RS09485 dbeb2e1e3766aa1aaf7905726ae5f21e 402 Gene3D G3DSA:3.20.20.140 76 393 2.0E-64 T 06-07-2017 BWK49_RS09485 dbeb2e1e3766aa1aaf7905726ae5f21e 402 Pfam PF04909 Amidohydrolase 99 384 4.6E-29 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 BWK49_RS05750 5ba9b0398a95714518efb750cb7fa775 426 SUPERFAMILY SSF48264 11 424 1.83E-79 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS05750 5ba9b0398a95714518efb750cb7fa775 426 Pfam PF00067 Cytochrome P450 257 385 1.6E-21 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS05750 5ba9b0398a95714518efb750cb7fa775 426 Gene3D G3DSA:1.10.630.10 9 424 4.2E-102 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS05750 5ba9b0398a95714518efb750cb7fa775 426 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 358 367 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 BWK49_RS05750 5ba9b0398a95714518efb750cb7fa775 426 PRINTS PR00359 B-class P450 signature 207 229 2.7E-39 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS05750 5ba9b0398a95714518efb750cb7fa775 426 PRINTS PR00359 B-class P450 signature 334 349 2.7E-39 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS05750 5ba9b0398a95714518efb750cb7fa775 426 PRINTS PR00359 B-class P450 signature 365 376 2.7E-39 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS05750 5ba9b0398a95714518efb750cb7fa775 426 PRINTS PR00359 B-class P450 signature 306 333 2.7E-39 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS05750 5ba9b0398a95714518efb750cb7fa775 426 PRINTS PR00359 B-class P450 signature 289 300 2.7E-39 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS05750 5ba9b0398a95714518efb750cb7fa775 426 PRINTS PR00359 B-class P450 signature 164 179 2.7E-39 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS05750 5ba9b0398a95714518efb750cb7fa775 426 PRINTS PR00359 B-class P450 signature 147 163 2.7E-39 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS05750 5ba9b0398a95714518efb750cb7fa775 426 PRINTS PR00359 B-class P450 signature 101 112 2.7E-39 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS05750 5ba9b0398a95714518efb750cb7fa775 426 PRINTS PR00359 B-class P450 signature 356 365 2.7E-39 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS11165 02a20ca62281ed19955fbfc0fbd48aa8 469 SUPERFAMILY SSF52777 38 153 2.45E-9 T 06-07-2017 BWK49_RS11165 02a20ca62281ed19955fbfc0fbd48aa8 469 Pfam PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain 4 260 3.3E-68 T 06-07-2017 IPR004255 O-acyltransferase, WSD1, N-terminal GO:0004144|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 BWK49_RS11165 02a20ca62281ed19955fbfc0fbd48aa8 469 Pfam PF06974 Protein of unknown function (DUF1298) 303 445 2.9E-24 T 06-07-2017 IPR009721 O-acyltransferase WSD1, C-terminal GO:0004144 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 BWK49_RS11165 02a20ca62281ed19955fbfc0fbd48aa8 469 TIGRFAM TIGR02946 acyl_WS_DGAT: acyltransferase, WS/DGAT/MGAT 4 449 1.5E-135 T 06-07-2017 IPR014292 Acyltransferase, WS/DGAT/MGAT GO:0016746|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 BWK49_RS26695 c1b3d40168589d4e4d7facb10bd5a1b2 156 Gene3D G3DSA:1.10.10.10 9 146 8.0E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS26695 c1b3d40168589d4e4d7facb10bd5a1b2 156 Pfam PF01047 MarR family 39 87 7.3E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 BWK49_RS26695 c1b3d40168589d4e4d7facb10bd5a1b2 156 SUPERFAMILY SSF46785 9 146 4.29E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS26695 c1b3d40168589d4e4d7facb10bd5a1b2 156 SMART SM00347 31 131 2.6E-17 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 BWK49_RS22450 e038fd762d7da4f732f55172598ea138 333 Gene3D G3DSA:3.20.20.30 20 331 6.6E-30 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS22450 e038fd762d7da4f732f55172598ea138 333 SUPERFAMILY SSF51679 18 331 4.21E-28 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS22450 e038fd762d7da4f732f55172598ea138 333 Pfam PF00296 Luciferase-like monooxygenase 18 309 7.0E-18 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS18890 2fd3443ea3cabf1afe1ddc600d5230ca 303 SUPERFAMILY SSF51366 27 276 8.0E-61 T 06-07-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 BWK49_RS18890 2fd3443ea3cabf1afe1ddc600d5230ca 303 TIGRFAM TIGR00343 TIGR00343: pyridoxal 5'-phosphate synthase, synthase subunit Pdx1 18 303 2.4E-144 T 06-07-2017 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 BWK49_RS18890 2fd3443ea3cabf1afe1ddc600d5230ca 303 PIRSF PIRSF029271 7 303 5.2E-150 T 06-07-2017 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 BWK49_RS18890 2fd3443ea3cabf1afe1ddc600d5230ca 303 Gene3D G3DSA:3.20.20.70 33 169 1.2E-47 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 BWK49_RS18890 2fd3443ea3cabf1afe1ddc600d5230ca 303 Gene3D G3DSA:3.20.20.70 201 287 1.2E-47 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 BWK49_RS18890 2fd3443ea3cabf1afe1ddc600d5230ca 303 Pfam PF01680 SOR/SNZ family 16 221 3.6E-106 T 06-07-2017 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 BWK49_RS18890 2fd3443ea3cabf1afe1ddc600d5230ca 303 Hamap MF_01824 Pyridoxal 5'-phosphate synthase subunit PdxS [pdxS]. 13 303 53.504 T 06-07-2017 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 BWK49_RS27540 ba07aaf3b6903196bf085b2de5eabf1d 201 Gene3D G3DSA:1.10.357.10 17 200 4.1E-25 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS27540 ba07aaf3b6903196bf085b2de5eabf1d 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 66 2.0E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS27540 ba07aaf3b6903196bf085b2de5eabf1d 201 SUPERFAMILY SSF46689 16 80 1.64E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS24385 bd78e4b21c917dd4b6bd4887f7f200a9 347 PIRSF PIRSF012608 1 347 2.3E-113 T 06-07-2017 IPR011200 Uncharacterised conserved protein UCP012608 BWK49_RS24385 bd78e4b21c917dd4b6bd4887f7f200a9 347 Pfam PF10094 Uncharacterized protein conserved in bacteria (DUF2332) 8 346 1.9E-109 T 06-07-2017 IPR011200 Uncharacterised conserved protein UCP012608 BWK49_RS03060 ddd3a530169a0d003597f60d1881295b 283 Gene3D G3DSA:3.20.20.20 5 272 7.2E-105 T 06-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 BWK49_RS03060 ddd3a530169a0d003597f60d1881295b 283 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 7 269 7.1E-94 T 06-07-2017 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 BWK49_RS03060 ddd3a530169a0d003597f60d1881295b 283 SUPERFAMILY SSF51717 6 271 5.76E-92 T 06-07-2017 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 BWK49_RS03060 ddd3a530169a0d003597f60d1881295b 283 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 8 23 - T 06-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 BWK49_RS03060 ddd3a530169a0d003597f60d1881295b 283 Pfam PF00809 Pterin binding enzyme 9 255 1.3E-85 T 06-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 BWK49_RS03060 ddd3a530169a0d003597f60d1881295b 283 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 42 55 - T 06-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 BWK49_RS09545 3ae7a79d877cf98e9967b7683b3615d6 414 Pfam PF00067 Cytochrome P450 192 379 4.6E-19 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS09545 3ae7a79d877cf98e9967b7683b3615d6 414 PRINTS PR00359 B-class P450 signature 196 218 9.1E-44 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS09545 3ae7a79d877cf98e9967b7683b3615d6 414 PRINTS PR00359 B-class P450 signature 282 293 9.1E-44 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS09545 3ae7a79d877cf98e9967b7683b3615d6 414 PRINTS PR00359 B-class P450 signature 299 326 9.1E-44 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS09545 3ae7a79d877cf98e9967b7683b3615d6 414 PRINTS PR00359 B-class P450 signature 327 342 9.1E-44 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS09545 3ae7a79d877cf98e9967b7683b3615d6 414 PRINTS PR00359 B-class P450 signature 154 169 9.1E-44 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS09545 3ae7a79d877cf98e9967b7683b3615d6 414 PRINTS PR00359 B-class P450 signature 358 369 9.1E-44 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS09545 3ae7a79d877cf98e9967b7683b3615d6 414 PRINTS PR00359 B-class P450 signature 137 153 9.1E-44 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS09545 3ae7a79d877cf98e9967b7683b3615d6 414 PRINTS PR00359 B-class P450 signature 349 358 9.1E-44 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS09545 3ae7a79d877cf98e9967b7683b3615d6 414 PRINTS PR00359 B-class P450 signature 91 102 9.1E-44 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS09545 3ae7a79d877cf98e9967b7683b3615d6 414 Gene3D G3DSA:1.10.630.10 15 412 7.4E-98 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS09545 3ae7a79d877cf98e9967b7683b3615d6 414 SUPERFAMILY SSF48264 19 411 2.1E-76 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS25105 ea88c5a56bb7d21be8de5d53ff3a0585 342 Gene3D G3DSA:3.40.50.720 163 335 1.3E-57 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS25105 ea88c5a56bb7d21be8de5d53ff3a0585 342 Gene3D G3DSA:3.40.50.720 1 130 1.3E-57 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS25105 ea88c5a56bb7d21be8de5d53ff3a0585 342 PRINTS PR01713 Nucleotide sugar epimerase signature 306 323 8.4E-5 T 06-07-2017 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-5609977|Reactome: R-HSA-70370 BWK49_RS25105 ea88c5a56bb7d21be8de5d53ff3a0585 342 PRINTS PR01713 Nucleotide sugar epimerase signature 244 259 8.4E-5 T 06-07-2017 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-5609977|Reactome: R-HSA-70370 BWK49_RS25105 ea88c5a56bb7d21be8de5d53ff3a0585 342 PRINTS PR01713 Nucleotide sugar epimerase signature 266 281 8.4E-5 T 06-07-2017 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-5609977|Reactome: R-HSA-70370 BWK49_RS25105 ea88c5a56bb7d21be8de5d53ff3a0585 342 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 264 1.3E-40 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 BWK49_RS25105 ea88c5a56bb7d21be8de5d53ff3a0585 342 SUPERFAMILY SSF51735 1 121 1.31E-71 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS25105 ea88c5a56bb7d21be8de5d53ff3a0585 342 SUPERFAMILY SSF51735 158 336 1.31E-71 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS25765 091878d7eceb1b383c9fc421a7901366 227 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 33 131 5.9E-6 T 06-07-2017 IPR000014 PAS domain BWK49_RS25765 091878d7eceb1b383c9fc421a7901366 227 Pfam PF08447 PAS fold 36 120 6.2E-10 T 06-07-2017 IPR013655 PAS fold-3 GO:0005515 BWK49_RS25765 091878d7eceb1b383c9fc421a7901366 227 Gene3D G3DSA:1.10.10.10 144 197 1.7E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS25765 091878d7eceb1b383c9fc421a7901366 227 SUPERFAMILY SSF52172 140 193 2.09E-6 T 06-07-2017 IPR011006 CheY-like superfamily BWK49_RS25765 091878d7eceb1b383c9fc421a7901366 227 SUPERFAMILY SSF55785 20 128 1.73E-13 T 06-07-2017 IPR000014 PAS domain BWK49_RS25765 091878d7eceb1b383c9fc421a7901366 227 Pfam PF03861 ANTAR domain 146 193 4.5E-18 T 06-07-2017 IPR005561 ANTAR domain GO:0003723 BWK49_RS25765 091878d7eceb1b383c9fc421a7901366 227 Gene3D G3DSA:3.30.450.20 20 127 3.8E-14 T 06-07-2017 BWK49_RS25765 091878d7eceb1b383c9fc421a7901366 227 SMART SM01012 138 193 6.7E-20 T 06-07-2017 IPR005561 ANTAR domain GO:0003723 BWK49_RS12965 ef9d6fda4e48fe93239669e98eeb61ff 240 Gene3D G3DSA:3.40.1130.10 1 204 1.6E-35 T 06-07-2017 BWK49_RS12965 ef9d6fda4e48fe93239669e98eeb61ff 240 SMART SM00563 35 154 2.1E-38 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 BWK49_RS12965 ef9d6fda4e48fe93239669e98eeb61ff 240 Pfam PF01553 Acyltransferase 21 151 8.1E-29 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 BWK49_RS12965 ef9d6fda4e48fe93239669e98eeb61ff 240 SUPERFAMILY SSF69593 2 217 1.18E-54 T 06-07-2017 BWK49_RS20520 96a7509f974c9dfc4379e2e496f31642 178 SUPERFAMILY SSF109604 22 96 1.91E-12 T 06-07-2017 BWK49_RS20520 96a7509f974c9dfc4379e2e496f31642 178 Pfam PF01966 HD domain 23 99 2.9E-7 T 06-07-2017 IPR006674 HD domain BWK49_RS20520 96a7509f974c9dfc4379e2e496f31642 178 Gene3D G3DSA:1.10.3210.10 11 105 1.2E-10 T 06-07-2017 IPR006674 HD domain BWK49_RS01795 df410861e794f8524db3b5a212fe364b 361 SUPERFAMILY SSF51182 8 342 3.82E-92 T 06-07-2017 IPR011051 RmlC-like cupin domain BWK49_RS01795 df410861e794f8524db3b5a212fe364b 361 Pfam PF07883 Cupin domain 91 160 7.1E-16 T 06-07-2017 IPR013096 Cupin 2, conserved barrel BWK49_RS01795 df410861e794f8524db3b5a212fe364b 361 Pfam PF07883 Cupin domain 259 326 2.9E-15 T 06-07-2017 IPR013096 Cupin 2, conserved barrel BWK49_RS01795 df410861e794f8524db3b5a212fe364b 361 Gene3D G3DSA:2.60.120.10 38 204 1.3E-39 T 06-07-2017 IPR014710 RmlC-like jelly roll fold BWK49_RS01795 df410861e794f8524db3b5a212fe364b 361 Gene3D G3DSA:2.60.120.10 212 355 2.8E-41 T 06-07-2017 IPR014710 RmlC-like jelly roll fold BWK49_RS17165 8c6a301bea5ef756bc50ff35bb28008a 480 SUPERFAMILY SSF50249 207 289 2.24E-27 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS17165 8c6a301bea5ef756bc50ff35bb28008a 480 Gene3D G3DSA:2.40.50.140 26 106 1.4E-19 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS17165 8c6a301bea5ef756bc50ff35bb28008a 480 SUPERFAMILY SSF50249 277 365 2.4E-24 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS17165 8c6a301bea5ef756bc50ff35bb28008a 480 Gene3D G3DSA:2.40.50.140 284 367 4.6E-28 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS17165 8c6a301bea5ef756bc50ff35bb28008a 480 SUPERFAMILY SSF50249 28 130 1.57E-22 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS17165 8c6a301bea5ef756bc50ff35bb28008a 480 SMART SM00316 207 277 2.0E-28 T 06-07-2017 IPR022967 RNA-binding domain, S1 BWK49_RS17165 8c6a301bea5ef756bc50ff35bb28008a 480 SMART SM00316 121 188 6.2E-11 T 06-07-2017 IPR022967 RNA-binding domain, S1 BWK49_RS17165 8c6a301bea5ef756bc50ff35bb28008a 480 SMART SM00316 34 105 3.9E-18 T 06-07-2017 IPR022967 RNA-binding domain, S1 BWK49_RS17165 8c6a301bea5ef756bc50ff35bb28008a 480 SMART SM00316 292 363 5.8E-24 T 06-07-2017 IPR022967 RNA-binding domain, S1 BWK49_RS17165 8c6a301bea5ef756bc50ff35bb28008a 480 Gene3D G3DSA:2.40.50.140 210 283 1.8E-30 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS17165 8c6a301bea5ef756bc50ff35bb28008a 480 Gene3D G3DSA:2.40.50.140 111 189 1.6E-15 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS17165 8c6a301bea5ef756bc50ff35bb28008a 480 PRINTS PR00681 Ribosomal protein S1 signature 102 121 1.9E-88 T 06-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 BWK49_RS17165 8c6a301bea5ef756bc50ff35bb28008a 480 PRINTS PR00681 Ribosomal protein S1 signature 307 326 1.9E-88 T 06-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 BWK49_RS17165 8c6a301bea5ef756bc50ff35bb28008a 480 PRINTS PR00681 Ribosomal protein S1 signature 143 160 1.9E-88 T 06-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 BWK49_RS17165 8c6a301bea5ef756bc50ff35bb28008a 480 PRINTS PR00681 Ribosomal protein S1 signature 346 364 1.9E-88 T 06-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 BWK49_RS17165 8c6a301bea5ef756bc50ff35bb28008a 480 PRINTS PR00681 Ribosomal protein S1 signature 172 192 1.9E-88 T 06-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 BWK49_RS17165 8c6a301bea5ef756bc50ff35bb28008a 480 PRINTS PR00681 Ribosomal protein S1 signature 126 142 1.9E-88 T 06-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 BWK49_RS17165 8c6a301bea5ef756bc50ff35bb28008a 480 PRINTS PR00681 Ribosomal protein S1 signature 36 54 1.9E-88 T 06-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 BWK49_RS17165 8c6a301bea5ef756bc50ff35bb28008a 480 PRINTS PR00681 Ribosomal protein S1 signature 54 68 1.9E-88 T 06-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 BWK49_RS17165 8c6a301bea5ef756bc50ff35bb28008a 480 PRINTS PR00681 Ribosomal protein S1 signature 229 250 1.9E-88 T 06-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 BWK49_RS17165 8c6a301bea5ef756bc50ff35bb28008a 480 Pfam PF00575 S1 RNA binding domain 291 363 1.2E-22 T 06-07-2017 IPR003029 S1 domain GO:0003676 BWK49_RS17165 8c6a301bea5ef756bc50ff35bb28008a 480 Pfam PF00575 S1 RNA binding domain 33 105 7.1E-17 T 06-07-2017 IPR003029 S1 domain GO:0003676 BWK49_RS17165 8c6a301bea5ef756bc50ff35bb28008a 480 Pfam PF00575 S1 RNA binding domain 206 277 1.5E-26 T 06-07-2017 IPR003029 S1 domain GO:0003676 BWK49_RS17165 8c6a301bea5ef756bc50ff35bb28008a 480 Pfam PF00575 S1 RNA binding domain 121 188 3.8E-15 T 06-07-2017 IPR003029 S1 domain GO:0003676 BWK49_RS17165 8c6a301bea5ef756bc50ff35bb28008a 480 SUPERFAMILY SSF50249 107 191 2.76E-14 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS14065 2db1b10076b4c60c2cd046b6310ec618 142 Gene3D G3DSA:2.60.40.290 40 139 3.2E-33 T 06-07-2017 IPR012291 Cellulose-binding family II/chitobiase, carbohydrate-binding domain GO:0004553|GO:0030247 BWK49_RS14065 2db1b10076b4c60c2cd046b6310ec618 142 Pfam PF00553 Cellulose binding domain 40 139 8.0E-33 T 06-07-2017 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 BWK49_RS14065 2db1b10076b4c60c2cd046b6310ec618 142 SMART SM00637 40 140 3.5E-37 T 06-07-2017 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 BWK49_RS14065 2db1b10076b4c60c2cd046b6310ec618 142 SUPERFAMILY SSF49384 36 140 6.63E-33 T 06-07-2017 IPR008965 Carbohydrate-binding domain GO:0030246 BWK49_RS00605 4b2dfde2ecd8ed2d2d6c1f467894c1a5 359 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 15 265 6.6E-51 T 06-07-2017 IPR005693 Virulence factor Mce protein BWK49_RS00605 4b2dfde2ecd8ed2d2d6c1f467894c1a5 359 Pfam PF02470 MlaD protein 36 109 9.9E-16 T 06-07-2017 IPR003399 Mce/MlaD BWK49_RS25675 29cda84276f621512b42ecccf68ada93 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 1.3E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS25675 29cda84276f621512b42ecccf68ada93 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 1.3E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS25675 29cda84276f621512b42ecccf68ada93 198 SUPERFAMILY SSF46689 5 74 7.7E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS25675 29cda84276f621512b42ecccf68ada93 198 Gene3D G3DSA:1.10.357.10 10 175 1.9E-22 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS25675 29cda84276f621512b42ecccf68ada93 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 57 9.8E-12 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS21670 55c249aaab9055bf98bac08133b23621 275 Pfam PF00296 Luciferase-like monooxygenase 18 216 1.1E-42 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS21670 55c249aaab9055bf98bac08133b23621 275 SUPERFAMILY SSF51679 17 269 6.8E-54 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS21670 55c249aaab9055bf98bac08133b23621 275 Gene3D G3DSA:3.20.20.30 16 270 3.9E-56 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS21670 55c249aaab9055bf98bac08133b23621 275 TIGRFAM TIGR03619 F420_Rv2161c: probable F420-dependent oxidoreductase, Rv2161c family 18 252 2.6E-77 T 06-07-2017 IPR019921 Luciferase-like, F420-dependent oxidoreductase, Rv2161c, predicted BWK49_RS11090 c03d3d82e4970d06d13990c6867f50bd 380 Gene3D G3DSA:3.40.47.10 142 180 7.1E-16 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS11090 c03d3d82e4970d06d13990c6867f50bd 380 Gene3D G3DSA:3.40.47.10 240 358 7.1E-16 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS11090 c03d3d82e4970d06d13990c6867f50bd 380 SUPERFAMILY SSF53901 3 225 1.8E-18 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS11090 c03d3d82e4970d06d13990c6867f50bd 380 PIRSF PIRSF000429 1 380 6.3E-24 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 BWK49_RS11090 c03d3d82e4970d06d13990c6867f50bd 380 SUPERFAMILY SSF53901 230 370 1.7E-25 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS11090 c03d3d82e4970d06d13990c6867f50bd 380 Pfam PF02803 Thiolase, C-terminal domain 242 356 2.7E-5 T 06-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 BWK49_RS11090 c03d3d82e4970d06d13990c6867f50bd 380 Gene3D G3DSA:3.40.47.10 19 107 2.6E-10 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS11090 c03d3d82e4970d06d13990c6867f50bd 380 Gene3D G3DSA:3.40.47.10 192 220 2.6E-10 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS07690 02a0404f239bacb874306bd09fdaf169 590 Pfam PF10081 Alpha/beta-hydrolase family 295 582 6.4E-131 T 06-07-2017 IPR027787 Alpha/beta-hydrolase, catalytic domain BWK49_RS07690 02a0404f239bacb874306bd09fdaf169 590 Pfam PF15420 Alpha/beta-hydrolase family N-terminus 71 278 3.4E-71 T 06-07-2017 IPR027788 Alpha/beta-hydrolase, N-terminal domain BWK49_RS07690 02a0404f239bacb874306bd09fdaf169 590 PIRSF PIRSF007542 13 590 4.3E-226 T 06-07-2017 IPR012037 Alpha/beta-hydrolase family BWK49_RS17635 3f2ffa44619ebf2e1868cd90fbe09194 315 Pfam PF00005 ABC transporter 22 165 6.6E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 BWK49_RS17635 3f2ffa44619ebf2e1868cd90fbe09194 315 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 13 308 1.2E-102 T 06-07-2017 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 BWK49_RS17635 3f2ffa44619ebf2e1868cd90fbe09194 315 SMART SM00382 31 228 1.6E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS17635 3f2ffa44619ebf2e1868cd90fbe09194 315 SUPERFAMILY SSF52540 5 227 2.04E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS17635 3f2ffa44619ebf2e1868cd90fbe09194 315 Gene3D G3DSA:3.40.50.300 5 235 8.0E-71 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS17635 3f2ffa44619ebf2e1868cd90fbe09194 315 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 BWK49_RS11130 338190a577879bdfc2885d689356f528 338 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 199 330 1.0E-21 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS11130 338190a577879bdfc2885d689356f528 338 Gene3D G3DSA:1.20.140.10 200 330 2.7E-26 T 06-07-2017 BWK49_RS11130 338190a577879bdfc2885d689356f528 338 Gene3D G3DSA:1.10.540.10 2 99 1.4E-8 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS11130 338190a577879bdfc2885d689356f528 338 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 99 3.0E-7 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS11130 338190a577879bdfc2885d689356f528 338 SUPERFAMILY SSF56645 2 178 2.54E-14 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS11130 338190a577879bdfc2885d689356f528 338 SUPERFAMILY SSF47203 193 332 4.19E-29 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS17115 94a1d392b55be3a709137ec42a7a5c84 679 SUPERFAMILY SSF56112 78 414 5.58E-64 T 06-07-2017 IPR011009 Protein kinase-like domain BWK49_RS17115 94a1d392b55be3a709137ec42a7a5c84 679 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 200 212 - T 06-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 BWK49_RS17115 94a1d392b55be3a709137ec42a7a5c84 679 Gene3D G3DSA:3.30.200.20 77 145 2.1E-17 T 06-07-2017 BWK49_RS17115 94a1d392b55be3a709137ec42a7a5c84 679 Pfam PF00069 Protein kinase domain 79 308 2.0E-38 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 BWK49_RS17115 94a1d392b55be3a709137ec42a7a5c84 679 Gene3D G3DSA:1.10.510.10 146 334 6.6E-40 T 06-07-2017 BWK49_RS17115 94a1d392b55be3a709137ec42a7a5c84 679 SMART SM00220 79 345 9.1E-46 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 BWK49_RS13575 d7ad6d3e4ee4cdfea8f13bd790f28727 235 Gene3D G3DSA:3.40.50.1820 2 229 3.2E-43 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS13575 d7ad6d3e4ee4cdfea8f13bd790f28727 235 SUPERFAMILY SSF53474 2 229 6.55E-37 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS13575 d7ad6d3e4ee4cdfea8f13bd790f28727 235 Pfam PF01738 Dienelactone hydrolase family 13 228 4.9E-54 T 06-07-2017 IPR002925 Dienelactone hydrolase GO:0016787 BWK49_RS10860 c4535237d2ee24bab1512fcbb446ea1a 410 Gene3D G3DSA:1.10.630.10 15 408 9.6E-104 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS10860 c4535237d2ee24bab1512fcbb446ea1a 410 Pfam PF00067 Cytochrome P450 205 377 6.0E-22 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS10860 c4535237d2ee24bab1512fcbb446ea1a 410 PRINTS PR00359 B-class P450 signature 94 105 5.2E-53 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS10860 c4535237d2ee24bab1512fcbb446ea1a 410 PRINTS PR00359 B-class P450 signature 197 219 5.2E-53 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS10860 c4535237d2ee24bab1512fcbb446ea1a 410 PRINTS PR00359 B-class P450 signature 359 370 5.2E-53 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS10860 c4535237d2ee24bab1512fcbb446ea1a 410 PRINTS PR00359 B-class P450 signature 156 171 5.2E-53 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS10860 c4535237d2ee24bab1512fcbb446ea1a 410 PRINTS PR00359 B-class P450 signature 282 293 5.2E-53 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS10860 c4535237d2ee24bab1512fcbb446ea1a 410 PRINTS PR00359 B-class P450 signature 327 342 5.2E-53 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS10860 c4535237d2ee24bab1512fcbb446ea1a 410 PRINTS PR00359 B-class P450 signature 139 155 5.2E-53 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS10860 c4535237d2ee24bab1512fcbb446ea1a 410 PRINTS PR00359 B-class P450 signature 299 326 5.2E-53 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS10860 c4535237d2ee24bab1512fcbb446ea1a 410 PRINTS PR00359 B-class P450 signature 350 359 5.2E-53 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS10860 c4535237d2ee24bab1512fcbb446ea1a 410 SUPERFAMILY SSF48264 22 409 3.41E-85 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS10860 c4535237d2ee24bab1512fcbb446ea1a 410 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 352 361 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 BWK49_RS21730 15d57a7add48b72d47e5a7adf861510d 96 Gene3D G3DSA:1.10.287.1060 2 91 2.8E-4 T 06-07-2017 BWK49_RS21730 15d57a7add48b72d47e5a7adf861510d 96 SUPERFAMILY SSF140453 1 94 6.93E-5 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like BWK49_RS15220 f5b6b7293a26a7178e9d97e4fdaf55c2 399 Pfam PF11203 Putative type VII ESX secretion system translocon, EccE 198 286 3.1E-21 T 06-07-2017 IPR021368 Type VII secretion system protein EccE BWK49_RS15220 f5b6b7293a26a7178e9d97e4fdaf55c2 399 TIGRFAM TIGR03923 T7SS_EccE: type VII secretion protein EccE 15 364 3.6E-107 T 06-07-2017 IPR021368 Type VII secretion system protein EccE BWK49_RS07430 c1eecf87487604d9c8ee1632b7347e39 544 Gene3D G3DSA:3.40.50.980 167 330 2.6E-32 T 06-07-2017 BWK49_RS07430 c1eecf87487604d9c8ee1632b7347e39 544 ProSitePatterns PS00455 Putative AMP-binding domain signature. 157 168 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS07430 c1eecf87487604d9c8ee1632b7347e39 544 SUPERFAMILY SSF56801 22 536 7.46E-95 T 06-07-2017 BWK49_RS07430 c1eecf87487604d9c8ee1632b7347e39 544 Gene3D G3DSA:2.30.38.10 363 434 7.9E-14 T 06-07-2017 BWK49_RS07430 c1eecf87487604d9c8ee1632b7347e39 544 Gene3D G3DSA:3.30.300.30 435 537 9.7E-20 T 06-07-2017 BWK49_RS07430 c1eecf87487604d9c8ee1632b7347e39 544 Pfam PF00501 AMP-binding enzyme 21 442 6.5E-67 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS07430 c1eecf87487604d9c8ee1632b7347e39 544 Gene3D G3DSA:3.40.50.980 28 166 5.8E-20 T 06-07-2017 BWK49_RS07430 c1eecf87487604d9c8ee1632b7347e39 544 Pfam PF14535 AMP-binding enzyme C-terminal domain 444 536 9.5E-7 T 06-07-2017 IPR028154 AMP-dependent ligase, C-terminal BWK49_RS27395 dd36cd573011f53d32467c0bfdf226ba 182 SUPERFAMILY SSF46689 15 82 1.48E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS27395 dd36cd573011f53d32467c0bfdf226ba 182 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 66 4.0E-13 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS27395 dd36cd573011f53d32467c0bfdf226ba 182 Gene3D G3DSA:1.10.357.10 15 173 4.7E-22 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS27395 dd36cd573011f53d32467c0bfdf226ba 182 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 1.1E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS27395 dd36cd573011f53d32467c0bfdf226ba 182 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 1.1E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS08880 a7eda208b04d44688efcaf4f2f242103 472 Gene3D G3DSA:2.40.37.10 320 471 2.6E-48 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 BWK49_RS08880 a7eda208b04d44688efcaf4f2f242103 472 PRINTS PR01181 Diaminopimelate decarboxylase signature 355 373 1.0E-25 T 06-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 BWK49_RS08880 a7eda208b04d44688efcaf4f2f242103 472 PRINTS PR01181 Diaminopimelate decarboxylase signature 112 129 1.0E-25 T 06-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 BWK49_RS08880 a7eda208b04d44688efcaf4f2f242103 472 PRINTS PR01181 Diaminopimelate decarboxylase signature 201 210 1.0E-25 T 06-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 BWK49_RS08880 a7eda208b04d44688efcaf4f2f242103 472 PRINTS PR01181 Diaminopimelate decarboxylase signature 438 460 1.0E-25 T 06-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 BWK49_RS08880 a7eda208b04d44688efcaf4f2f242103 472 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 268 285 - T 06-07-2017 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site BWK49_RS08880 a7eda208b04d44688efcaf4f2f242103 472 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 44 471 1.4E-148 T 06-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 BWK49_RS08880 a7eda208b04d44688efcaf4f2f242103 472 Gene3D G3DSA:3.20.20.10 72 319 1.2E-84 T 06-07-2017 IPR029066 PLP-binding barrel BWK49_RS08880 a7eda208b04d44688efcaf4f2f242103 472 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 322 341 1.6E-15 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 BWK49_RS08880 a7eda208b04d44688efcaf4f2f242103 472 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 94 112 1.6E-15 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 BWK49_RS08880 a7eda208b04d44688efcaf4f2f242103 472 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 428 441 1.6E-15 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 BWK49_RS08880 a7eda208b04d44688efcaf4f2f242103 472 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 114 126 1.6E-15 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 BWK49_RS08880 a7eda208b04d44688efcaf4f2f242103 472 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 229 242 1.6E-15 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 BWK49_RS08880 a7eda208b04d44688efcaf4f2f242103 472 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 340 447 1.5E-15 T 06-07-2017 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 BWK49_RS08880 a7eda208b04d44688efcaf4f2f242103 472 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 71 332 7.4E-58 T 06-07-2017 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 BWK49_RS08880 a7eda208b04d44688efcaf4f2f242103 472 SUPERFAMILY SSF50621 315 471 7.12E-51 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 BWK49_RS08880 a7eda208b04d44688efcaf4f2f242103 472 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 94 112 - T 06-07-2017 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site BWK49_RS08880 a7eda208b04d44688efcaf4f2f242103 472 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 53 471 39.243 T 06-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 BWK49_RS08880 a7eda208b04d44688efcaf4f2f242103 472 SUPERFAMILY SSF51419 64 333 1.6E-71 T 06-07-2017 IPR029066 PLP-binding barrel BWK49_RS27330 e9b4f0b6c204ca93fb475ec3ff676f6d 322 Gene3D G3DSA:3.90.180.10 18 147 1.8E-16 T 06-07-2017 IPR011032 GroES-like BWK49_RS27330 e9b4f0b6c204ca93fb475ec3ff676f6d 322 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 92 2.1E-4 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 BWK49_RS27330 e9b4f0b6c204ca93fb475ec3ff676f6d 322 SUPERFAMILY SSF50129 17 154 6.39E-21 T 06-07-2017 IPR011032 GroES-like BWK49_RS27330 e9b4f0b6c204ca93fb475ec3ff676f6d 322 Pfam PF00107 Zinc-binding dehydrogenase 156 272 1.3E-15 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 BWK49_RS27330 e9b4f0b6c204ca93fb475ec3ff676f6d 322 SUPERFAMILY SSF51735 126 280 2.18E-26 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS27330 e9b4f0b6c204ca93fb475ec3ff676f6d 322 Gene3D G3DSA:3.40.50.720 148 263 2.8E-25 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS12775 f943acc0c0516dbfb84a8982c0125c2d 233 PIRSF PIRSF016262 8 228 2.4E-62 T 06-07-2017 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 BWK49_RS12775 f943acc0c0516dbfb84a8982c0125c2d 233 Hamap MF_00013 Octanoyltransferase [lipB]. 11 217 33.788 T 06-07-2017 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 BWK49_RS12775 f943acc0c0516dbfb84a8982c0125c2d 233 SUPERFAMILY SSF55681 13 217 1.33E-67 T 06-07-2017 BWK49_RS12775 f943acc0c0516dbfb84a8982c0125c2d 233 ProSitePatterns PS01313 Lipoate-protein ligase B signature. 76 91 - T 06-07-2017 IPR020605 Octanoyltransferase, conserved site GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 BWK49_RS12775 f943acc0c0516dbfb84a8982c0125c2d 233 Pfam PF03099 Biotin/lipoate A/B protein ligase family 66 169 1.8E-8 T 06-07-2017 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 BWK49_RS12775 f943acc0c0516dbfb84a8982c0125c2d 233 ProDom PD006086 LIGASE LIPOATE-PROTEIN B TRANSFERASE ACYLTRANSFERASE LIPOYLTRANSFERASE LIPOYL-ACYL-CARRIER 2.3.1.- PROTEIN-PROTEIN- N-LIPOYLTRANSFERASE 80 132 2.0E-22 T 06-07-2017 BWK49_RS12775 f943acc0c0516dbfb84a8982c0125c2d 233 Gene3D G3DSA:3.90.1550.10 10 214 1.2E-73 T 06-07-2017 BWK49_RS12775 f943acc0c0516dbfb84a8982c0125c2d 233 TIGRFAM TIGR00214 lipB: lipoyl(octanoyl) transferase 41 212 1.2E-39 T 06-07-2017 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 BWK49_RS05765 f25e901d3a3490c903040740d5c37eb4 235 Pfam PF01427 D-ala-D-ala dipeptidase 42 234 5.2E-61 T 06-07-2017 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 BWK49_RS05765 f25e901d3a3490c903040740d5c37eb4 235 SUPERFAMILY SSF55166 43 231 1.14E-46 T 06-07-2017 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 BWK49_RS05765 f25e901d3a3490c903040740d5c37eb4 235 Hamap MF_01924 D-alanyl-D-alanine dipeptidase [ddpX]. 44 233 24.65 T 06-07-2017 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 BWK49_RS05765 f25e901d3a3490c903040740d5c37eb4 235 Gene3D G3DSA:3.30.1380.10 43 221 3.0E-47 T 06-07-2017 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 BWK49_RS11500 6f78c4ff6c3fa9b6d6ad8584c0ebb2b8 463 Gene3D G3DSA:3.30.930.10 11 364 3.6E-143 T 06-07-2017 BWK49_RS11500 6f78c4ff6c3fa9b6d6ad8584c0ebb2b8 463 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 160 300 1.9E-7 T 06-07-2017 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 BWK49_RS11500 6f78c4ff6c3fa9b6d6ad8584c0ebb2b8 463 SUPERFAMILY SSF52954 356 461 2.11E-32 T 06-07-2017 IPR004154 Anticodon-binding BWK49_RS11500 6f78c4ff6c3fa9b6d6ad8584c0ebb2b8 463 Pfam PF03129 Anticodon binding domain 369 458 5.9E-21 T 06-07-2017 IPR004154 Anticodon-binding BWK49_RS11500 6f78c4ff6c3fa9b6d6ad8584c0ebb2b8 463 Gene3D G3DSA:3.40.50.800 365 460 5.6E-38 T 06-07-2017 IPR004154 Anticodon-binding BWK49_RS11500 6f78c4ff6c3fa9b6d6ad8584c0ebb2b8 463 SUPERFAMILY SSF55681 9 372 2.11E-118 T 06-07-2017 BWK49_RS11500 6f78c4ff6c3fa9b6d6ad8584c0ebb2b8 463 Hamap MF_00253_B Glycine--tRNA ligase [glyQS]. 6 461 48.616 T 06-07-2017 IPR022961 Glycine-tRNA ligase, bacterial GO:0004820 KEGG: 00970+6.1.1.14 BWK49_RS11500 6f78c4ff6c3fa9b6d6ad8584c0ebb2b8 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 161 178 4.0E-55 T 06-07-2017 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 BWK49_RS11500 6f78c4ff6c3fa9b6d6ad8584c0ebb2b8 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 140 152 4.0E-55 T 06-07-2017 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 BWK49_RS11500 6f78c4ff6c3fa9b6d6ad8584c0ebb2b8 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 193 210 4.0E-55 T 06-07-2017 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 BWK49_RS11500 6f78c4ff6c3fa9b6d6ad8584c0ebb2b8 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 28 42 4.0E-55 T 06-07-2017 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 BWK49_RS11500 6f78c4ff6c3fa9b6d6ad8584c0ebb2b8 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 210 220 4.0E-55 T 06-07-2017 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 BWK49_RS11500 6f78c4ff6c3fa9b6d6ad8584c0ebb2b8 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 320 332 4.0E-55 T 06-07-2017 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 BWK49_RS11500 6f78c4ff6c3fa9b6d6ad8584c0ebb2b8 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 406 425 4.0E-55 T 06-07-2017 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 BWK49_RS11500 6f78c4ff6c3fa9b6d6ad8584c0ebb2b8 463 TIGRFAM TIGR00389 glyS_dimeric: glycine--tRNA ligase 10 239 3.0E-77 T 06-07-2017 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 BWK49_RS23690 80da567480252f8d6af7f67230dd1164 198 SUPERFAMILY SSF46689 13 88 1.2E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS23690 80da567480252f8d6af7f67230dd1164 198 Gene3D G3DSA:1.10.357.10 8 181 7.6E-27 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS23690 80da567480252f8d6af7f67230dd1164 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 66 4.8E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS23690 80da567480252f8d6af7f67230dd1164 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 35 4.8E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS23690 80da567480252f8d6af7f67230dd1164 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 68 2.8E-14 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS21900 ddba6f0258ae5b606392c020fdeec3d7 389 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 305 385 3.0E-14 T 06-07-2017 IPR022171 PPE family, C-terminal BWK49_RS21900 ddba6f0258ae5b606392c020fdeec3d7 389 SUPERFAMILY SSF140459 2 169 1.52E-58 T 06-07-2017 BWK49_RS21900 ddba6f0258ae5b606392c020fdeec3d7 389 Pfam PF00823 PPE family 6 160 9.0E-58 T 06-07-2017 IPR000030 PPE family BWK49_RS02595 6a05145cd56bd5ceddba566fa256af66 239 Pfam PF03551 Transcriptional regulator PadR-like family 105 173 7.5E-21 T 06-07-2017 IPR005149 Transcription regulator PadR, N-terminal BWK49_RS02595 6a05145cd56bd5ceddba566fa256af66 239 SUPERFAMILY SSF46785 90 186 7.64E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS02595 6a05145cd56bd5ceddba566fa256af66 239 Gene3D G3DSA:1.10.10.10 96 178 2.4E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS06255 328c6caa8e3f3fe99b2bb84eb2e83f2f 204 Gene3D G3DSA:1.10.357.10 8 203 1.3E-29 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS06255 328c6caa8e3f3fe99b2bb84eb2e83f2f 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 69 6.2E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS06255 328c6caa8e3f3fe99b2bb84eb2e83f2f 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 1.9E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS06255 328c6caa8e3f3fe99b2bb84eb2e83f2f 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 1.9E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS06255 328c6caa8e3f3fe99b2bb84eb2e83f2f 204 SUPERFAMILY SSF46689 11 93 4.09E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS09910 f9679d645686541d8623b58bd6bc439e 500 SUPERFAMILY SSF54534 169 280 3.93E-23 T 06-07-2017 BWK49_RS09910 f9679d645686541d8623b58bd6bc439e 500 TIGRFAM TIGR00115 tig: trigger factor 48 451 4.2E-119 T 06-07-2017 IPR005215 Trigger factor GO:0015031 BWK49_RS09910 f9679d645686541d8623b58bd6bc439e 500 Hamap MF_00303 Trigger factor [tig]. 37 460 19.095 T 06-07-2017 IPR005215 Trigger factor GO:0015031 BWK49_RS09910 f9679d645686541d8623b58bd6bc439e 500 Gene3D G3DSA:3.30.70.1050 38 155 2.3E-31 T 06-07-2017 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 BWK49_RS09910 f9679d645686541d8623b58bd6bc439e 500 SUPERFAMILY SSF109998 282 471 4.4E-38 T 06-07-2017 IPR027304 Trigger factor/SurA domain BWK49_RS09910 f9679d645686541d8623b58bd6bc439e 500 SUPERFAMILY SSF102735 38 162 8.63E-32 T 06-07-2017 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 BWK49_RS09910 f9679d645686541d8623b58bd6bc439e 500 Gene3D G3DSA:3.10.50.40 193 246 2.1E-5 T 06-07-2017 BWK49_RS09910 f9679d645686541d8623b58bd6bc439e 500 Pfam PF05697 Bacterial trigger factor protein (TF) 38 180 8.0E-37 T 06-07-2017 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 BWK49_RS09910 f9679d645686541d8623b58bd6bc439e 500 Gene3D G3DSA:1.10.3120.10 247 430 6.3E-44 T 06-07-2017 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 BWK49_RS09910 f9679d645686541d8623b58bd6bc439e 500 PIRSF PIRSF003095 37 481 3.1E-121 T 06-07-2017 IPR005215 Trigger factor GO:0015031 BWK49_RS09910 f9679d645686541d8623b58bd6bc439e 500 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 195 253 1.2E-5 T 06-07-2017 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 BWK49_RS09910 f9679d645686541d8623b58bd6bc439e 500 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 294 453 3.2E-38 T 06-07-2017 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 BWK49_RS22565 1d7e88cc4dc762960fe137fe99da9fb6 314 Gene3D G3DSA:1.10.10.60 262 309 2.0E-7 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS22565 1d7e88cc4dc762960fe137fe99da9fb6 314 SUPERFAMILY SSF46689 260 310 7.17E-7 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS22565 1d7e88cc4dc762960fe137fe99da9fb6 314 SMART SM00342 224 306 1.8E-21 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 BWK49_RS22565 1d7e88cc4dc762960fe137fe99da9fb6 314 SUPERFAMILY SSF46689 210 257 7.67E-8 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS22565 1d7e88cc4dc762960fe137fe99da9fb6 314 Gene3D G3DSA:3.40.50.880 2 213 4.4E-58 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like BWK49_RS22565 1d7e88cc4dc762960fe137fe99da9fb6 314 Pfam PF12833 Helix-turn-helix domain 230 308 3.2E-18 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 BWK49_RS22565 1d7e88cc4dc762960fe137fe99da9fb6 314 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 261 302 - T 06-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 BWK49_RS22565 1d7e88cc4dc762960fe137fe99da9fb6 314 Gene3D G3DSA:1.10.10.60 214 261 2.1E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS22565 1d7e88cc4dc762960fe137fe99da9fb6 314 Pfam PF01965 DJ-1/PfpI family 2 168 6.8E-26 T 06-07-2017 IPR002818 DJ-1/PfpI BWK49_RS22565 1d7e88cc4dc762960fe137fe99da9fb6 314 SUPERFAMILY SSF52317 2 188 5.35E-50 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like BWK49_RS03590 bf2d606e322395b30d31605d612c5e10 289 Pfam PF00106 short chain dehydrogenase 1 191 4.2E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS03590 bf2d606e322395b30d31605d612c5e10 289 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 1.4E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS03590 bf2d606e322395b30d31605d612c5e10 289 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 1.4E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS03590 bf2d606e322395b30d31605d612c5e10 289 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 73 84 1.4E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS03590 bf2d606e322395b30d31605d612c5e10 289 Gene3D G3DSA:3.40.50.720 1 241 6.7E-60 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS03590 bf2d606e322395b30d31605d612c5e10 289 SUPERFAMILY SSF51735 1 243 2.62E-56 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS03590 bf2d606e322395b30d31605d612c5e10 289 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS03590 bf2d606e322395b30d31605d612c5e10 289 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 73 84 1.3E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS03590 bf2d606e322395b30d31605d612c5e10 289 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 1.3E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS03590 bf2d606e322395b30d31605d612c5e10 289 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 1.3E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS03590 bf2d606e322395b30d31605d612c5e10 289 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 1.3E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS17665 1a33ec026186f7232fb9ad9bd2cea0a2 183 Gene3D G3DSA:2.60.120.10 1 175 5.0E-65 T 06-07-2017 IPR014710 RmlC-like jelly roll fold BWK49_RS17665 1a33ec026186f7232fb9ad9bd2cea0a2 183 SUPERFAMILY SSF51182 1 176 3.72E-59 T 06-07-2017 IPR011051 RmlC-like cupin domain BWK49_RS17665 1a33ec026186f7232fb9ad9bd2cea0a2 183 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 1 172 3.0E-53 T 06-07-2017 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 BWK49_RS17665 1a33ec026186f7232fb9ad9bd2cea0a2 183 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 6 174 2.5E-55 T 06-07-2017 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 BWK49_RS06310 7d6aabc3e82926857e18367ed4d78e94 454 PRINTS PR00359 B-class P450 signature 306 333 2.8E-26 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS06310 7d6aabc3e82926857e18367ed4d78e94 454 PRINTS PR00359 B-class P450 signature 364 375 2.8E-26 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS06310 7d6aabc3e82926857e18367ed4d78e94 454 PRINTS PR00359 B-class P450 signature 167 182 2.8E-26 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS06310 7d6aabc3e82926857e18367ed4d78e94 454 PRINTS PR00359 B-class P450 signature 334 349 2.8E-26 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS06310 7d6aabc3e82926857e18367ed4d78e94 454 PRINTS PR00359 B-class P450 signature 355 364 2.8E-26 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS06310 7d6aabc3e82926857e18367ed4d78e94 454 PRINTS PR00359 B-class P450 signature 104 115 2.8E-26 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS06310 7d6aabc3e82926857e18367ed4d78e94 454 PRINTS PR00359 B-class P450 signature 289 300 2.8E-26 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS06310 7d6aabc3e82926857e18367ed4d78e94 454 PRINTS PR00359 B-class P450 signature 150 166 2.8E-26 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS06310 7d6aabc3e82926857e18367ed4d78e94 454 Pfam PF00067 Cytochrome P450 228 384 1.4E-14 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS06310 7d6aabc3e82926857e18367ed4d78e94 454 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 357 366 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 BWK49_RS06310 7d6aabc3e82926857e18367ed4d78e94 454 Gene3D G3DSA:1.10.630.10 18 417 3.3E-90 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS06310 7d6aabc3e82926857e18367ed4d78e94 454 SUPERFAMILY SSF48264 27 416 9.17E-74 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS08950 953021999ea209b42c8578851494d26b 177 Pfam PF00430 ATP synthase B/B' CF(0) 28 158 7.2E-32 T 06-07-2017 IPR002146 ATPase, F0 complex, subunit B/B', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 BWK49_RS08950 953021999ea209b42c8578851494d26b 177 Hamap MF_01398 ATP synthase subunit b [atpF]. 23 174 10.024 T 06-07-2017 IPR002146 ATPase, F0 complex, subunit B/B', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 BWK49_RS08950 953021999ea209b42c8578851494d26b 177 SUPERFAMILY SSF81573 84 143 2.35E-9 T 06-07-2017 IPR028987 F-type ATP synthase subunit B-like, membrane domain BWK49_RS08950 953021999ea209b42c8578851494d26b 177 Gene3D G3DSA:1.20.5.620 85 144 8.4E-7 T 06-07-2017 IPR028987 F-type ATP synthase subunit B-like, membrane domain BWK49_RS09790 eb751175d0e4471a77d240443e006fc1 596 SUPERFAMILY SSF56784 35 225 5.86E-26 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS09790 eb751175d0e4471a77d240443e006fc1 596 SUPERFAMILY SSF69593 303 482 8.63E-36 T 06-07-2017 BWK49_RS09790 eb751175d0e4471a77d240443e006fc1 596 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 38 236 4.4E-62 T 06-07-2017 IPR006385 HAD-superfamily hydrolase, subfamily IB, PSPase-like, bacterial BWK49_RS09790 eb751175d0e4471a77d240443e006fc1 596 SMART SM00563 325 439 5.4E-34 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 BWK49_RS09790 eb751175d0e4471a77d240443e006fc1 596 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 38 224 1.8E-19 T 06-07-2017 IPR006383 HAD-superfamily hydrolase, subfamily IB, PSPase-like GO:0008152|GO:0016791 BWK49_RS09790 eb751175d0e4471a77d240443e006fc1 596 Gene3D G3DSA:3.40.50.1000 105 251 3.5E-37 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS09790 eb751175d0e4471a77d240443e006fc1 596 Gene3D G3DSA:3.40.1130.10 315 472 5.6E-23 T 06-07-2017 BWK49_RS09790 eb751175d0e4471a77d240443e006fc1 596 Pfam PF01553 Acyltransferase 310 436 1.2E-28 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 BWK49_RS09790 eb751175d0e4471a77d240443e006fc1 596 Pfam PF12710 haloacid dehalogenase-like hydrolase 38 221 8.9E-30 T 06-07-2017 BWK49_RS11960 454253621885cabf31517398c1c33f8d 310 Pfam PF04072 Leucine carboxyl methyltransferase 19 204 6.9E-70 T 06-07-2017 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 BWK49_RS11960 454253621885cabf31517398c1c33f8d 310 Gene3D G3DSA:3.40.50.150 13 230 8.6E-19 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS11960 454253621885cabf31517398c1c33f8d 310 SUPERFAMILY SSF53335 15 291 8.75E-83 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS11960 454253621885cabf31517398c1c33f8d 310 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 17 285 6.0E-84 T 06-07-2017 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 BWK49_RS02720 f294bce3ed04193e4eebef10a7c1b7fa 194 Gene3D G3DSA:3.40.1350.10 69 187 2.8E-37 T 06-07-2017 IPR011856 tRNA endonuclease-like domain GO:0003676|GO:0004518 Reactome: R-HSA-6784531 BWK49_RS02720 f294bce3ed04193e4eebef10a7c1b7fa 194 Pfam PF04471 Restriction endonuclease 75 183 4.5E-28 T 06-07-2017 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 BWK49_RS02720 f294bce3ed04193e4eebef10a7c1b7fa 194 SUPERFAMILY SSF52980 79 184 7.51E-25 T 06-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 BWK49_RS14945 27b83b78ce7559f9a4d97e37cb4fdc23 254 SUPERFAMILY SSF161098 2 242 1.2E-47 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS14945 27b83b78ce7559f9a4d97e37cb4fdc23 254 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 59 242 1.8E-17 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS14945 27b83b78ce7559f9a4d97e37cb4fdc23 254 TIGRFAM TIGR01581 Mo_ABC_porter: NifC-like ABC-type porter 21 240 1.2E-85 T 06-07-2017 IPR006469 NifC-like ABC-type porter GO:0005215|GO:0006810|GO:0016020 BWK49_RS14945 27b83b78ce7559f9a4d97e37cb4fdc23 254 Gene3D G3DSA:1.10.3720.10 4 241 4.6E-41 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS14945 27b83b78ce7559f9a4d97e37cb4fdc23 254 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 42 242 5.5E-66 T 06-07-2017 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 BWK49_RS24835 2b8a794b54829f171b26125aca5e3008 287 Pfam PF01435 Peptidase family M48 69 284 2.0E-37 T 06-07-2017 IPR001915 Peptidase M48 GO:0004222|GO:0006508 BWK49_RS24835 2b8a794b54829f171b26125aca5e3008 287 Gene3D G3DSA:3.30.2010.10 61 151 1.6E-31 T 06-07-2017 BWK49_RS24835 2b8a794b54829f171b26125aca5e3008 287 Hamap MF_00188 Protease HtpX [htpX]. 9 284 28.071 T 06-07-2017 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 BWK49_RS20965 ce8d22d9f24f3b398d3ce8aba1b43f24 503 SUPERFAMILY SSF55931 21 322 4.84E-110 T 06-07-2017 BWK49_RS20965 ce8d22d9f24f3b398d3ce8aba1b43f24 503 Gene3D G3DSA:1.10.10.410 447 497 1.5E-4 T 06-07-2017 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal BWK49_RS20965 ce8d22d9f24f3b398d3ce8aba1b43f24 503 Pfam PF02934 GatB/GatE catalytic domain 22 315 6.9E-105 T 06-07-2017 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 BWK49_RS20965 ce8d22d9f24f3b398d3ce8aba1b43f24 503 Pfam PF02637 GatB domain 354 497 1.2E-36 T 06-07-2017 IPR018027 Asn/Gln amidotransferase GO:0016884 BWK49_RS20965 ce8d22d9f24f3b398d3ce8aba1b43f24 503 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 18 501 35.429 T 06-07-2017 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 BWK49_RS20965 ce8d22d9f24f3b398d3ce8aba1b43f24 503 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 19 496 7.4E-142 T 06-07-2017 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 BWK49_RS20965 ce8d22d9f24f3b398d3ce8aba1b43f24 503 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 167 181 - T 06-07-2017 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 BWK49_RS20965 ce8d22d9f24f3b398d3ce8aba1b43f24 503 SMART SM00845 353 500 8.3E-50 T 06-07-2017 IPR018027 Asn/Gln amidotransferase GO:0016884 BWK49_RS20965 ce8d22d9f24f3b398d3ce8aba1b43f24 503 SUPERFAMILY SSF89095 353 498 2.75E-21 T 06-07-2017 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 BWK49_RS21700 a1bc7df5368545e7b2e0b01b191cc587 484 Pfam PF00614 Phospholipase D Active site motif 135 156 5.3E-7 T 06-07-2017 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 BWK49_RS21700 a1bc7df5368545e7b2e0b01b191cc587 484 SUPERFAMILY SSF56024 204 391 3.14E-24 T 06-07-2017 BWK49_RS21700 a1bc7df5368545e7b2e0b01b191cc587 484 Pfam PF13091 PLD-like domain 260 388 2.2E-10 T 06-07-2017 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148 BWK49_RS21700 a1bc7df5368545e7b2e0b01b191cc587 484 SUPERFAMILY SSF56024 6 243 5.34E-25 T 06-07-2017 BWK49_RS21700 a1bc7df5368545e7b2e0b01b191cc587 484 SMART SM00155 345 372 0.004 T 06-07-2017 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 BWK49_RS21700 a1bc7df5368545e7b2e0b01b191cc587 484 SMART SM00155 132 159 0.0059 T 06-07-2017 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 BWK49_RS21700 a1bc7df5368545e7b2e0b01b191cc587 484 Gene3D G3DSA:3.30.870.10 259 389 1.2E-19 T 06-07-2017 BWK49_RS21700 a1bc7df5368545e7b2e0b01b191cc587 484 Gene3D G3DSA:3.30.870.10 17 239 1.1E-23 T 06-07-2017 BWK49_RS10205 52d45839c9e78824bd267a5edde321a7 623 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 63 78 - T 06-07-2017 IPR031157 Tr-type G domain, conserved site BWK49_RS10205 52d45839c9e78824bd267a5edde321a7 623 SUPERFAMILY SSF54980 418 513 1.53E-22 T 06-07-2017 IPR009022 Elongation factor G, III-V domain BWK49_RS10205 52d45839c9e78824bd267a5edde321a7 623 SUPERFAMILY SSF50447 185 306 9.84E-24 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain BWK49_RS10205 52d45839c9e78824bd267a5edde321a7 623 Gene3D G3DSA:3.40.50.300 20 213 2.6E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS10205 52d45839c9e78824bd267a5edde321a7 623 TIGRFAM TIGR01393 lepA: elongation factor 4 24 614 3.8E-296 T 06-07-2017 IPR006297 Elongation factor 4 GO:0005525 BWK49_RS10205 52d45839c9e78824bd267a5edde321a7 623 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 26 196 2.2E-17 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 BWK49_RS10205 52d45839c9e78824bd267a5edde321a7 623 Hamap MF_00071 Elongation factor 4 [lepA]. 1 620 279.124 T 06-07-2017 IPR006297 Elongation factor 4 GO:0005525 BWK49_RS10205 52d45839c9e78824bd267a5edde321a7 623 Pfam PF00009 Elongation factor Tu GTP binding domain 24 201 2.9E-50 T 06-07-2017 BWK49_RS10205 52d45839c9e78824bd267a5edde321a7 623 PRINTS PR00315 GTP-binding elongation factor signature 146 155 3.7E-13 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 BWK49_RS10205 52d45839c9e78824bd267a5edde321a7 623 PRINTS PR00315 GTP-binding elongation factor signature 70 78 3.7E-13 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 BWK49_RS10205 52d45839c9e78824bd267a5edde321a7 623 PRINTS PR00315 GTP-binding elongation factor signature 94 104 3.7E-13 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 BWK49_RS10205 52d45839c9e78824bd267a5edde321a7 623 PRINTS PR00315 GTP-binding elongation factor signature 27 40 3.7E-13 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 BWK49_RS10205 52d45839c9e78824bd267a5edde321a7 623 PRINTS PR00315 GTP-binding elongation factor signature 110 121 3.7E-13 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 BWK49_RS10205 52d45839c9e78824bd267a5edde321a7 623 SMART SM00838 417 501 0.0014 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain BWK49_RS10205 52d45839c9e78824bd267a5edde321a7 623 SUPERFAMILY SSF54980 311 390 4.68E-18 T 06-07-2017 IPR009022 Elongation factor G, III-V domain BWK49_RS10205 52d45839c9e78824bd267a5edde321a7 623 SUPERFAMILY SSF52540 18 222 1.04E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS10205 52d45839c9e78824bd267a5edde321a7 623 Gene3D G3DSA:3.30.70.240 420 509 1.7E-20 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain BWK49_RS10205 52d45839c9e78824bd267a5edde321a7 623 Gene3D G3DSA:3.30.70.870 311 388 6.1E-24 T 06-07-2017 BWK49_RS10205 52d45839c9e78824bd267a5edde321a7 623 Gene3D G3DSA:2.40.30.10 214 309 1.8E-19 T 06-07-2017 BWK49_RS10205 52d45839c9e78824bd267a5edde321a7 623 Pfam PF06421 GTP-binding protein LepA C-terminus 508 612 9.0E-48 T 06-07-2017 IPR013842 GTP-binding protein LepA, C-terminal BWK49_RS10205 52d45839c9e78824bd267a5edde321a7 623 Pfam PF00679 Elongation factor G C-terminus 418 504 3.5E-21 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain BWK49_RS17985 dfdfce946067438212fe00fbc97dd2f3 36 SUPERFAMILY SSF53901 2 31 1.86E-5 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS17985 dfdfce946067438212fe00fbc97dd2f3 36 ProSitePatterns PS00099 Thiolases active site. 14 27 - T 06-07-2017 IPR020610 Thiolase, active site GO:0008152|GO:0016747 BWK49_RS17985 dfdfce946067438212fe00fbc97dd2f3 36 Gene3D G3DSA:3.40.47.10 1 32 2.0E-7 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS17985 dfdfce946067438212fe00fbc97dd2f3 36 Pfam PF02803 Thiolase, C-terminal domain 2 31 5.4E-7 T 06-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 BWK49_RS02115 8b15393c426116cca0aebc2211b8d9e7 627 SMART SM00849 102 325 1.1E-23 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS02115 8b15393c426116cca0aebc2211b8d9e7 627 Pfam PF14863 Alkyl sulfatase dimerisation 362 500 7.4E-58 T 06-07-2017 IPR029228 Alkyl sulfatase dimerisation domain GO:0046983 BWK49_RS02115 8b15393c426116cca0aebc2211b8d9e7 627 Gene3D G3DSA:3.60.15.10 229 349 2.8E-41 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS02115 8b15393c426116cca0aebc2211b8d9e7 627 Gene3D G3DSA:3.60.15.10 68 193 2.8E-41 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS02115 8b15393c426116cca0aebc2211b8d9e7 627 SUPERFAMILY SSF55718 510 627 7.95E-22 T 06-07-2017 IPR003033 SCP2 sterol-binding domain BWK49_RS02115 8b15393c426116cca0aebc2211b8d9e7 627 Pfam PF14864 Alkyl sulfatase C-terminal 508 627 2.5E-32 T 06-07-2017 IPR029229 Alkyl sulfatase, C-terminal BWK49_RS02115 8b15393c426116cca0aebc2211b8d9e7 627 SUPERFAMILY SSF56281 17 501 1.82E-147 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS02115 8b15393c426116cca0aebc2211b8d9e7 627 Pfam PF00753 Metallo-beta-lactamase superfamily 98 325 3.6E-38 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS03290 c8e8547fc8a1f5ecfd19f4c871947079 276 SUPERFAMILY SSF54001 2 258 7.6E-82 T 06-07-2017 BWK49_RS03290 c8e8547fc8a1f5ecfd19f4c871947079 276 Gene3D G3DSA:3.30.2140.10 187 270 5.2E-52 T 06-07-2017 BWK49_RS03290 c8e8547fc8a1f5ecfd19f4c871947079 276 Gene3D G3DSA:3.30.2140.10 2 86 5.2E-52 T 06-07-2017 BWK49_RS03290 c8e8547fc8a1f5ecfd19f4c871947079 276 Pfam PF00797 N-acetyltransferase 21 258 3.1E-79 T 06-07-2017 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 BWK49_RS09335 965257931f5d69d2bbba58a27b3ef8cc 404 SUPERFAMILY SSF89796 1 403 4.84E-93 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS09335 965257931f5d69d2bbba58a27b3ef8cc 404 Gene3D G3DSA:3.40.50.10540 312 403 1.3E-75 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS09335 965257931f5d69d2bbba58a27b3ef8cc 404 Gene3D G3DSA:3.40.50.10540 1 219 1.3E-75 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS09335 965257931f5d69d2bbba58a27b3ef8cc 404 Pfam PF02515 CoA-transferase family III 1 380 1.1E-78 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 BWK49_RS09335 965257931f5d69d2bbba58a27b3ef8cc 404 Gene3D G3DSA:3.30.1540.10 239 311 1.4E-7 T 06-07-2017 BWK49_RS24505 6eae74c910fc9181bc809416c02acd26 232 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 62 2.9E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS24505 6eae74c910fc9181bc809416c02acd26 232 SUPERFAMILY SSF46689 10 74 4.41E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS24505 6eae74c910fc9181bc809416c02acd26 232 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 9.5E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS24505 6eae74c910fc9181bc809416c02acd26 232 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 9.5E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS24505 6eae74c910fc9181bc809416c02acd26 232 Gene3D G3DSA:1.10.357.10 11 203 6.4E-39 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS24505 6eae74c910fc9181bc809416c02acd26 232 Pfam PF13305 WHG domain 89 190 1.1E-10 T 06-07-2017 IPR025996 WHG domain BWK49_RS24505 6eae74c910fc9181bc809416c02acd26 232 SUPERFAMILY SSF48498 85 210 1.38E-20 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS01120 498324bf674be402fb17caa2ca5960c0 540 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 220 373 1.8E-8 T 06-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 BWK49_RS01120 498324bf674be402fb17caa2ca5960c0 540 Pfam PF08310 LGFP repeat 420 471 4.8E-16 T 06-07-2017 IPR013207 LGFP BWK49_RS01120 498324bf674be402fb17caa2ca5960c0 540 SMART SM00701 196 344 2.9E-61 T 06-07-2017 IPR006619 Peptidoglycan recognition protein family domain, metazoa/bacteria GO:0008270|GO:0008745|GO:0009253 BWK49_RS01120 498324bf674be402fb17caa2ca5960c0 540 SUPERFAMILY SSF55846 196 388 3.27E-49 T 06-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 BWK49_RS01120 498324bf674be402fb17caa2ca5960c0 540 Gene3D G3DSA:3.40.80.10 192 389 1.2E-48 T 06-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 BWK49_RS21785 328b9f8d616410c8e0ded9212459120e 153 Gene3D G3DSA:2.60.40.1240 30 152 3.4E-37 T 06-07-2017 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain BWK49_RS21785 328b9f8d616410c8e0ded9212459120e 153 ProDom PD886639 ANTIGEN IMMUNOGENIC EXTRACELLULAR MPT63 MPB63 PRECURSOR IMMUNOPROTECTIVE SIGNAL SEQUENCING DIRECT 32 153 1.0E-45 T 06-07-2017 IPR015250 MPT63-like GO:0005615 BWK49_RS21785 328b9f8d616410c8e0ded9212459120e 153 SUPERFAMILY SSF81982 30 152 4.84E-35 T 06-07-2017 IPR015250 MPT63-like GO:0005615 BWK49_RS21785 328b9f8d616410c8e0ded9212459120e 153 Pfam PF09167 Domain of unknown function (DUF1942) 32 151 6.6E-36 T 06-07-2017 IPR015250 MPT63-like GO:0005615 BWK49_RS26155 770c9b973b6a136fb8a0fdc1a00910c2 515 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 64 499 6.6E-94 T 06-07-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 BWK49_RS26155 770c9b973b6a136fb8a0fdc1a00910c2 515 ProSitePatterns PS00217 Sugar transport proteins signature 2. 166 191 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 BWK49_RS26155 770c9b973b6a136fb8a0fdc1a00910c2 515 Pfam PF00083 Sugar (and other) transporter 71 501 6.0E-94 T 06-07-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 BWK49_RS26155 770c9b973b6a136fb8a0fdc1a00910c2 515 PRINTS PR00171 Sugar transporter signature 315 325 1.2E-15 T 06-07-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 BWK49_RS26155 770c9b973b6a136fb8a0fdc1a00910c2 515 PRINTS PR00171 Sugar transporter signature 427 439 1.2E-15 T 06-07-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 BWK49_RS26155 770c9b973b6a136fb8a0fdc1a00910c2 515 PRINTS PR00171 Sugar transporter signature 78 88 1.2E-15 T 06-07-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 BWK49_RS26155 770c9b973b6a136fb8a0fdc1a00910c2 515 PRINTS PR00171 Sugar transporter signature 161 180 1.2E-15 T 06-07-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 BWK49_RS26155 770c9b973b6a136fb8a0fdc1a00910c2 515 SUPERFAMILY SSF103473 67 501 8.89E-66 T 06-07-2017 IPR020846 Major facilitator superfamily domain BWK49_RS26155 770c9b973b6a136fb8a0fdc1a00910c2 515 Gene3D G3DSA:1.20.1250.20 73 252 3.8E-26 T 06-07-2017 BWK49_RS26155 770c9b973b6a136fb8a0fdc1a00910c2 515 Gene3D G3DSA:1.20.1250.20 306 500 2.9E-16 T 06-07-2017 BWK49_RS17740 517a889b3130e248754b7dcb4b8015b3 422 Gene3D G3DSA:3.40.50.2000 1 259 2.1E-59 T 06-07-2017 BWK49_RS17740 517a889b3130e248754b7dcb4b8015b3 422 SUPERFAMILY SSF53756 1 417 5.5E-90 T 06-07-2017 BWK49_RS17740 517a889b3130e248754b7dcb4b8015b3 422 Gene3D G3DSA:3.40.50.2000 260 395 2.0E-8 T 06-07-2017 BWK49_RS23260 34fe103fa0dfb1593d58b5fd90b5139c 1537 Pfam PF06224 Winged helix DNA-binding domain 908 1068 3.7E-6 T 06-07-2017 IPR009351 Protein of unknown function DUF1006 BWK49_RS23260 34fe103fa0dfb1593d58b5fd90b5139c 1537 SUPERFAMILY SSF52540 43 298 1.11E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS23260 34fe103fa0dfb1593d58b5fd90b5139c 1537 SUPERFAMILY SSF52540 334 407 1.11E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS23260 34fe103fa0dfb1593d58b5fd90b5139c 1537 Pfam PF00270 DEAD/DEAH box helicase 35 216 5.2E-27 T 06-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 BWK49_RS23260 34fe103fa0dfb1593d58b5fd90b5139c 1537 Gene3D G3DSA:3.40.50.300 22 231 2.9E-45 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS23260 34fe103fa0dfb1593d58b5fd90b5139c 1537 SMART SM00382 47 390 5.6E-4 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS23260 34fe103fa0dfb1593d58b5fd90b5139c 1537 Gene3D G3DSA:3.40.50.300 268 298 9.3E-28 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS23260 34fe103fa0dfb1593d58b5fd90b5139c 1537 Gene3D G3DSA:3.40.50.300 334 420 9.3E-28 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS23260 34fe103fa0dfb1593d58b5fd90b5139c 1537 Pfam PF00271 Helicase conserved C-terminal domain 330 403 1.2E-12 T 06-07-2017 IPR001650 Helicase, C-terminal BWK49_RS23260 34fe103fa0dfb1593d58b5fd90b5139c 1537 SMART SM00487 30 243 1.7E-37 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain BWK49_RS23260 34fe103fa0dfb1593d58b5fd90b5139c 1537 SMART SM00490 290 403 9.0E-14 T 06-07-2017 IPR001650 Helicase, C-terminal BWK49_RS23260 34fe103fa0dfb1593d58b5fd90b5139c 1537 Pfam PF08494 DEAD/H associated 665 862 2.7E-71 T 06-07-2017 IPR013701 DEAD/H associated GO:0005524|GO:0016818 BWK49_RS22135 36df9498e90b74c87d4e214855e17b74 252 Gene3D G3DSA:3.30.750.24 11 118 8.4E-9 T 06-07-2017 IPR002645 STAS domain BWK49_RS22135 36df9498e90b74c87d4e214855e17b74 252 SUPERFAMILY SSF52091 11 119 1.31E-11 T 06-07-2017 IPR002645 STAS domain BWK49_RS00465 b01e15c471d625e2525cfb934c6403e6 261 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 24 255 8.2E-59 T 06-07-2017 BWK49_RS00465 b01e15c471d625e2525cfb934c6403e6 261 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 15 199 9.8E-5 T 06-07-2017 BWK49_RS00465 b01e15c471d625e2525cfb934c6403e6 261 SUPERFAMILY SSF51735 13 255 8.42E-79 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS00465 b01e15c471d625e2525cfb934c6403e6 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 184 201 1.1E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS00465 b01e15c471d625e2525cfb934c6403e6 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 90 101 1.1E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS00465 b01e15c471d625e2525cfb934c6403e6 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 182 1.1E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS00465 b01e15c471d625e2525cfb934c6403e6 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 137 153 1.1E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS00465 b01e15c471d625e2525cfb934c6403e6 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 16 33 1.1E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS00465 b01e15c471d625e2525cfb934c6403e6 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 220 240 1.1E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS00465 b01e15c471d625e2525cfb934c6403e6 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 90 101 1.4E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS00465 b01e15c471d625e2525cfb934c6403e6 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 143 151 1.4E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS00465 b01e15c471d625e2525cfb934c6403e6 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 163 182 1.4E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS00465 b01e15c471d625e2525cfb934c6403e6 261 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 150 178 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS00465 b01e15c471d625e2525cfb934c6403e6 261 Gene3D G3DSA:3.40.50.720 8 255 1.4E-83 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS02710 d9c107d3c2f997a23f4bf463c536211e 230 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 104 183 1.6E-6 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 BWK49_RS02710 d9c107d3c2f997a23f4bf463c536211e 230 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 11 188 1.2E-9 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 BWK49_RS02710 d9c107d3c2f997a23f4bf463c536211e 230 Gene3D G3DSA:3.40.50.1000 10 27 5.8E-32 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS02710 d9c107d3c2f997a23f4bf463c536211e 230 Gene3D G3DSA:3.40.50.1000 65 218 5.8E-32 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS02710 d9c107d3c2f997a23f4bf463c536211e 230 SUPERFAMILY SSF56784 11 219 3.8E-47 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS02710 d9c107d3c2f997a23f4bf463c536211e 230 Pfam PF13419 Haloacid dehalogenase-like hydrolase 12 188 3.3E-24 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS03245 ceb1b51385615cdf91caf91b06173b65 718 Gene3D G3DSA:1.10.540.10 5 100 1.8E-11 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS03245 ceb1b51385615cdf91caf91b06173b65 718 Gene3D G3DSA:1.10.540.10 389 460 1.3E-11 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS03245 ceb1b51385615cdf91caf91b06173b65 718 SUPERFAMILY SSF47203 570 716 1.19E-9 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS03245 ceb1b51385615cdf91caf91b06173b65 718 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 370 460 1.1E-9 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS03245 ceb1b51385615cdf91caf91b06173b65 718 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 99 1.6E-10 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS03245 ceb1b51385615cdf91caf91b06173b65 718 Gene3D G3DSA:1.20.140.10 211 344 6.6E-29 T 06-07-2017 BWK49_RS03245 ceb1b51385615cdf91caf91b06173b65 718 Gene3D G3DSA:2.40.110.10 463 559 1.1E-33 T 06-07-2017 BWK49_RS03245 ceb1b51385615cdf91caf91b06173b65 718 Gene3D G3DSA:1.20.140.10 560 718 3.7E-19 T 06-07-2017 BWK49_RS03245 ceb1b51385615cdf91caf91b06173b65 718 SUPERFAMILY SSF56645 4 188 1.24E-14 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS03245 ceb1b51385615cdf91caf91b06173b65 718 SUPERFAMILY SSF56645 376 583 4.71E-60 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS03245 ceb1b51385615cdf91caf91b06173b65 718 SUPERFAMILY SSF47203 210 342 6.44E-30 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS03245 ceb1b51385615cdf91caf91b06173b65 718 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 464 546 4.9E-19 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 BWK49_RS03245 ceb1b51385615cdf91caf91b06173b65 718 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 212 344 1.8E-20 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS03245 ceb1b51385615cdf91caf91b06173b65 718 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 570 714 9.3E-10 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS23700 506b423a3c6e9f13ed7b447850258975 270 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 4.9E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS23700 506b423a3c6e9f13ed7b447850258975 270 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 4.9E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS23700 506b423a3c6e9f13ed7b447850258975 270 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 4.9E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS23700 506b423a3c6e9f13ed7b447850258975 270 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 22 249 8.7E-59 T 06-07-2017 BWK49_RS23700 506b423a3c6e9f13ed7b447850258975 270 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS23700 506b423a3c6e9f13ed7b447850258975 270 Gene3D G3DSA:3.40.50.720 10 250 6.5E-79 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS23700 506b423a3c6e9f13ed7b447850258975 270 SUPERFAMILY SSF51735 12 250 6.63E-77 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS23700 506b423a3c6e9f13ed7b447850258975 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 3.1E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS23700 506b423a3c6e9f13ed7b447850258975 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 3.1E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS23700 506b423a3c6e9f13ed7b447850258975 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 3.1E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS23700 506b423a3c6e9f13ed7b447850258975 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 3.1E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS23700 506b423a3c6e9f13ed7b447850258975 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 3.1E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS23700 506b423a3c6e9f13ed7b447850258975 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 3.1E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS17760 26602d0dad45b65c2f429354b2ac9dc3 232 SUPERFAMILY SSF53335 24 231 2.28E-29 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS17760 26602d0dad45b65c2f429354b2ac9dc3 232 Pfam PF04989 Cephalosporin hydroxylase 37 231 2.5E-68 T 06-07-2017 IPR007072 Rhamnosyl O-methyltransferase/Cephalosporin hydroxylase GO:0008168|GO:0008610 BWK49_RS17760 26602d0dad45b65c2f429354b2ac9dc3 232 Gene3D G3DSA:3.40.50.150 64 209 1.4E-7 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS24265 4265106c9681eff7c6fdb3edc255844b 502 Pfam PF02720 Domain of unknown function (DUF222) 40 342 1.3E-82 T 06-07-2017 IPR003870 Domain of unknown function DUF222 BWK49_RS24265 4265106c9681eff7c6fdb3edc255844b 502 SMART SM00507 333 385 8.8E-7 T 06-07-2017 IPR003615 HNH nuclease BWK49_RS11940 9df0b9fdf016e2f37e29810f1b866e1e 856 Gene3D G3DSA:3.30.565.10 772 853 9.4E-7 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS11940 9df0b9fdf016e2f37e29810f1b866e1e 856 Gene3D G3DSA:3.30.450.40 27 190 1.2E-20 T 06-07-2017 IPR029016 GAF domain-like BWK49_RS11940 9df0b9fdf016e2f37e29810f1b866e1e 856 Pfam PF13581 Histidine kinase-like ATPase domain 737 852 7.0E-22 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS11940 9df0b9fdf016e2f37e29810f1b866e1e 856 SUPERFAMILY SSF55781 33 204 5.23E-25 T 06-07-2017 IPR029016 GAF domain-like BWK49_RS11940 9df0b9fdf016e2f37e29810f1b866e1e 856 Gene3D G3DSA:3.30.450.40 191 350 4.9E-18 T 06-07-2017 IPR029016 GAF domain-like BWK49_RS11940 9df0b9fdf016e2f37e29810f1b866e1e 856 Pfam PF13185 GAF domain 50 178 1.8E-9 T 06-07-2017 IPR003018 GAF domain GO:0005515 BWK49_RS11940 9df0b9fdf016e2f37e29810f1b866e1e 856 Pfam PF13185 GAF domain 213 347 3.9E-10 T 06-07-2017 IPR003018 GAF domain GO:0005515 BWK49_RS11940 9df0b9fdf016e2f37e29810f1b866e1e 856 SUPERFAMILY SSF55874 767 851 1.03E-9 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS11940 9df0b9fdf016e2f37e29810f1b866e1e 856 SMART SM00331 514 729 1.3E-36 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 BWK49_RS11940 9df0b9fdf016e2f37e29810f1b866e1e 856 SUPERFAMILY SSF81606 531 722 8.11E-8 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 BWK49_RS11940 9df0b9fdf016e2f37e29810f1b866e1e 856 SUPERFAMILY SSF55781 194 362 1.92E-18 T 06-07-2017 IPR029016 GAF domain-like BWK49_RS11940 9df0b9fdf016e2f37e29810f1b866e1e 856 SMART SM00065 51 187 5.3E-7 T 06-07-2017 IPR003018 GAF domain GO:0005515 BWK49_RS11940 9df0b9fdf016e2f37e29810f1b866e1e 856 SMART SM00065 208 357 0.012 T 06-07-2017 IPR003018 GAF domain GO:0005515 BWK49_RS11940 9df0b9fdf016e2f37e29810f1b866e1e 856 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 544 729 1.4E-45 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 BWK49_RS00550 adb54ff6589cbcf74394e6b85753dca5 225 SMART SM00419 167 214 2.5E-11 T 06-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 BWK49_RS00550 adb54ff6589cbcf74394e6b85753dca5 225 SMART SM00100 10 128 3.8E-31 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain BWK49_RS00550 adb54ff6589cbcf74394e6b85753dca5 225 SUPERFAMILY SSF46785 145 223 1.99E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS00550 adb54ff6589cbcf74394e6b85753dca5 225 SUPERFAMILY SSF51206 3 142 5.24E-36 T 06-07-2017 IPR018490 Cyclic nucleotide-binding-like BWK49_RS00550 adb54ff6589cbcf74394e6b85753dca5 225 Gene3D G3DSA:1.10.10.10 144 223 2.6E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS00550 adb54ff6589cbcf74394e6b85753dca5 225 Pfam PF13545 Crp-like helix-turn-helix domain 148 221 2.7E-16 T 06-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 BWK49_RS00550 adb54ff6589cbcf74394e6b85753dca5 225 Pfam PF00027 Cyclic nucleotide-binding domain 29 114 2.9E-22 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain BWK49_RS00550 adb54ff6589cbcf74394e6b85753dca5 225 Gene3D G3DSA:2.60.120.10 2 141 1.9E-36 T 06-07-2017 IPR014710 RmlC-like jelly roll fold BWK49_RS17335 1c7e00c8d1c48d246127f0fc9e9795e4 467 Gene3D G3DSA:3.40.50.1980 38 276 1.5E-74 T 06-07-2017 BWK49_RS17335 1c7e00c8d1c48d246127f0fc9e9795e4 467 SUPERFAMILY SSF53720 37 465 7.85E-67 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 BWK49_RS17335 1c7e00c8d1c48d246127f0fc9e9795e4 467 Pfam PF00815 Histidinol dehydrogenase 33 465 2.1E-151 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 BWK49_RS17335 1c7e00c8d1c48d246127f0fc9e9795e4 467 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 266 298 - T 06-07-2017 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 BWK49_RS17335 1c7e00c8d1c48d246127f0fc9e9795e4 467 PRINTS PR00083 Histidinol dehydrogenase signature 399 417 1.8E-43 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 BWK49_RS17335 1c7e00c8d1c48d246127f0fc9e9795e4 467 PRINTS PR00083 Histidinol dehydrogenase signature 288 307 1.8E-43 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 BWK49_RS17335 1c7e00c8d1c48d246127f0fc9e9795e4 467 PRINTS PR00083 Histidinol dehydrogenase signature 266 287 1.8E-43 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 BWK49_RS17335 1c7e00c8d1c48d246127f0fc9e9795e4 467 PRINTS PR00083 Histidinol dehydrogenase signature 45 69 1.8E-43 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 BWK49_RS17335 1c7e00c8d1c48d246127f0fc9e9795e4 467 PRINTS PR00083 Histidinol dehydrogenase signature 358 383 1.8E-43 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 BWK49_RS17335 1c7e00c8d1c48d246127f0fc9e9795e4 467 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 17 465 37.72 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 BWK49_RS17335 1c7e00c8d1c48d246127f0fc9e9795e4 467 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 239 464 8.1E-85 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 BWK49_RS10165 2e09c957aa346bb24150e98c1615bb62 86 Pfam PF01649 Ribosomal protein S20 2 84 1.5E-27 T 06-07-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS10165 2e09c957aa346bb24150e98c1615bb62 86 TIGRFAM TIGR00029 S20: ribosomal protein bS20 2 86 1.4E-24 T 06-07-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS10165 2e09c957aa346bb24150e98c1615bb62 86 SUPERFAMILY SSF46992 3 86 8.76E-28 T 06-07-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS10165 2e09c957aa346bb24150e98c1615bb62 86 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 14 86 7.0E-32 T 06-07-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS10165 2e09c957aa346bb24150e98c1615bb62 86 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 17.057 T 06-07-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS10165 2e09c957aa346bb24150e98c1615bb62 86 Gene3D G3DSA:1.20.58.110 2 86 8.7E-29 T 06-07-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS24445 22da36d94c17a3ce556f97fe759e507e 125 Pfam PF11259 Protein of unknown function (DUF3060) 55 113 4.2E-19 T 06-07-2017 IPR021417 Protein of unknown function DUF3060 BWK49_RS21065 2f75ebbb72b451984436c62904cef632 392 Pfam PF00266 Aminotransferase class-V 2 370 1.6E-60 T 06-07-2017 IPR000192 Aminotransferase class V domain BWK49_RS21065 2f75ebbb72b451984436c62904cef632 392 Gene3D G3DSA:3.90.1150.10 250 375 1.2E-40 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 BWK49_RS21065 2f75ebbb72b451984436c62904cef632 392 PIRSF PIRSF005572 1 385 1.8E-110 T 06-07-2017 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 BWK49_RS21065 2f75ebbb72b451984436c62904cef632 392 Gene3D G3DSA:3.40.640.10 14 249 2.7E-73 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 BWK49_RS21065 2f75ebbb72b451984436c62904cef632 392 SUPERFAMILY SSF53383 1 379 5.66E-94 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase BWK49_RS21850 0947d320aeb0d41d6504dde7a9d88c3c 458 SUPERFAMILY SSF51971 304 445 1.77E-10 T 06-07-2017 BWK49_RS21850 0947d320aeb0d41d6504dde7a9d88c3c 458 Gene3D G3DSA:3.40.50.720 324 455 5.1E-75 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS21850 0947d320aeb0d41d6504dde7a9d88c3c 458 Gene3D G3DSA:3.40.50.720 3 100 5.1E-75 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS21850 0947d320aeb0d41d6504dde7a9d88c3c 458 PRINTS PR00419 Adrenodoxin reductase family signature 78 88 1.8E-14 T 06-07-2017 BWK49_RS21850 0947d320aeb0d41d6504dde7a9d88c3c 458 PRINTS PR00419 Adrenodoxin reductase family signature 5 27 1.8E-14 T 06-07-2017 BWK49_RS21850 0947d320aeb0d41d6504dde7a9d88c3c 458 PRINTS PR00419 Adrenodoxin reductase family signature 150 164 1.8E-14 T 06-07-2017 BWK49_RS21850 0947d320aeb0d41d6504dde7a9d88c3c 458 PIRSF PIRSF000362 1 458 1.0E-166 T 06-07-2017 IPR021163 Ferredoxin-NADP+ reductase, adrenodoxin-type GO:0016491|GO:0055114 Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 BWK49_RS21850 0947d320aeb0d41d6504dde7a9d88c3c 458 SUPERFAMILY SSF51971 3 216 3.3E-60 T 06-07-2017 BWK49_RS21850 0947d320aeb0d41d6504dde7a9d88c3c 458 SUPERFAMILY SSF51971 264 324 3.3E-60 T 06-07-2017 BWK49_RS21850 0947d320aeb0d41d6504dde7a9d88c3c 458 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 166 7.5E-10 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS21850 0947d320aeb0d41d6504dde7a9d88c3c 458 Gene3D G3DSA:3.50.50.60 101 323 3.4E-78 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS03225 f69960bfbd1a404bccff1903c1ad1fa2 273 SUPERFAMILY SSF52540 12 242 1.01E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS03225 f69960bfbd1a404bccff1903c1ad1fa2 273 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 BWK49_RS03225 f69960bfbd1a404bccff1903c1ad1fa2 273 Pfam PF00005 ABC transporter 32 180 6.8E-24 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 BWK49_RS03225 f69960bfbd1a404bccff1903c1ad1fa2 273 Gene3D G3DSA:3.40.50.300 10 246 7.0E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS03225 f69960bfbd1a404bccff1903c1ad1fa2 273 SMART SM00382 40 230 1.9E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS12625 316fce78f3a77e1d7e1390990bc0eb4f 446 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 234 249 - T 06-07-2017 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 BWK49_RS12625 316fce78f3a77e1d7e1390990bc0eb4f 446 SMART SM01230 106 357 6.8E-125 T 06-07-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 BWK49_RS12625 316fce78f3a77e1d7e1390990bc0eb4f 446 Pfam PF00120 Glutamine synthetase, catalytic domain 107 443 4.6E-126 T 06-07-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 BWK49_RS12625 316fce78f3a77e1d7e1390990bc0eb4f 446 SUPERFAMILY SSF54368 7 104 6.41E-29 T 06-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 BWK49_RS12625 316fce78f3a77e1d7e1390990bc0eb4f 446 SUPERFAMILY SSF55931 108 445 6.77E-117 T 06-07-2017 BWK49_RS12625 316fce78f3a77e1d7e1390990bc0eb4f 446 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 8 444 3.1E-132 T 06-07-2017 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 BWK49_RS12625 316fce78f3a77e1d7e1390990bc0eb4f 446 Gene3D G3DSA:3.10.20.70 5 109 1.3E-37 T 06-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 BWK49_RS12625 316fce78f3a77e1d7e1390990bc0eb4f 446 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 16 100 1.2E-25 T 06-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 BWK49_RS12625 316fce78f3a77e1d7e1390990bc0eb4f 446 Gene3D G3DSA:3.30.590.10 110 435 4.0E-115 T 06-07-2017 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 BWK49_RS07145 d4bb034899e790dfb0ce8d392b00b6c6 159 SUPERFAMILY SSF46785 2 148 2.17E-31 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS07145 d4bb034899e790dfb0ce8d392b00b6c6 159 Pfam PF12802 MarR family 36 96 6.4E-15 T 06-07-2017 BWK49_RS07145 d4bb034899e790dfb0ce8d392b00b6c6 159 SMART SM00347 30 133 4.7E-10 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 BWK49_RS07145 d4bb034899e790dfb0ce8d392b00b6c6 159 Gene3D G3DSA:1.10.10.10 4 151 1.8E-35 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS06215 ca2e28fac56a2a7b70dd78758aca33e8 381 Gene3D G3DSA:3.20.20.140 21 369 1.1E-42 T 06-07-2017 BWK49_RS06215 ca2e28fac56a2a7b70dd78758aca33e8 381 Pfam PF04909 Amidohydrolase 94 367 2.2E-25 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 BWK49_RS06215 ca2e28fac56a2a7b70dd78758aca33e8 381 SUPERFAMILY SSF51556 75 367 2.45E-50 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS06215 ca2e28fac56a2a7b70dd78758aca33e8 381 SUPERFAMILY SSF51556 19 47 2.45E-50 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS14715 b2487b99155fb41c238dd80d97fc5215 337 Pfam PF00107 Zinc-binding dehydrogenase 177 299 9.6E-22 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 BWK49_RS14715 b2487b99155fb41c238dd80d97fc5215 337 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 134 1.7E-29 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 BWK49_RS14715 b2487b99155fb41c238dd80d97fc5215 337 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 06-07-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 BWK49_RS14715 b2487b99155fb41c238dd80d97fc5215 337 SMART SM00829 13 335 5.0E-7 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 BWK49_RS14715 b2487b99155fb41c238dd80d97fc5215 337 Gene3D G3DSA:3.90.180.10 3 169 3.0E-59 T 06-07-2017 IPR011032 GroES-like BWK49_RS14715 b2487b99155fb41c238dd80d97fc5215 337 SUPERFAMILY SSF50129 9 166 1.07E-49 T 06-07-2017 IPR011032 GroES-like BWK49_RS14715 b2487b99155fb41c238dd80d97fc5215 337 Gene3D G3DSA:3.40.50.720 170 284 1.9E-26 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS14715 b2487b99155fb41c238dd80d97fc5215 337 SUPERFAMILY SSF51735 140 300 4.98E-40 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS25635 398df9b2f9c7f9876c064e22a12bd7d9 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 6 19 4.4E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS25635 398df9b2f9c7f9876c064e22a12bd7d9 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 50 4.4E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS25635 398df9b2f9c7f9876c064e22a12bd7d9 188 Pfam PF00440 Bacterial regulatory proteins, tetR family 6 52 9.9E-16 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS25635 398df9b2f9c7f9876c064e22a12bd7d9 188 SUPERFAMILY SSF46689 4 63 2.05E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS25635 398df9b2f9c7f9876c064e22a12bd7d9 188 Gene3D G3DSA:1.10.10.60 4 51 2.8E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS25635 398df9b2f9c7f9876c064e22a12bd7d9 188 Gene3D G3DSA:1.10.357.10 56 182 4.9E-35 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS25635 398df9b2f9c7f9876c064e22a12bd7d9 188 SUPERFAMILY SSF48498 71 182 8.15E-28 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS26485 9b78b1175aff8e41271511e1904feef2 54 SUPERFAMILY SSF57829 4 54 4.03E-17 T 06-07-2017 IPR011332 Zinc-binding ribosomal protein GO:0006412 BWK49_RS26485 9b78b1175aff8e41271511e1904feef2 54 Pfam PF00471 Ribosomal protein L33 10 54 2.0E-16 T 06-07-2017 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS26485 9b78b1175aff8e41271511e1904feef2 54 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 2 54 14.454 T 06-07-2017 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS26485 9b78b1175aff8e41271511e1904feef2 54 ProSitePatterns PS00582 Ribosomal protein L33 signature. 22 41 - T 06-07-2017 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS26485 9b78b1175aff8e41271511e1904feef2 54 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 1 54 3.6E-23 T 06-07-2017 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS21335 2549572429ae3fa9357aeb588ca308ea 150 PIRSF PIRSF005087 6 144 2.0E-54 T 06-07-2017 IPR004465 Ribonucleotide reductase Class Ib, NrdI BWK49_RS21335 2549572429ae3fa9357aeb588ca308ea 150 TIGRFAM TIGR00333 nrdI: nrdI protein 9 138 2.7E-49 T 06-07-2017 IPR004465 Ribonucleotide reductase Class Ib, NrdI BWK49_RS21335 2549572429ae3fa9357aeb588ca308ea 150 Pfam PF07972 NrdI Flavodoxin like 9 130 1.4E-45 T 06-07-2017 IPR004465 Ribonucleotide reductase Class Ib, NrdI BWK49_RS21335 2549572429ae3fa9357aeb588ca308ea 150 Hamap MF_00128 Protein NrdI [nrdI]. 7 140 35.559 T 06-07-2017 IPR020852 Ribonucleotide reductase, class Ib, NrdI, bacterial BWK49_RS21335 2549572429ae3fa9357aeb588ca308ea 150 SUPERFAMILY SSF52218 6 140 6.12E-24 T 06-07-2017 IPR029039 Flavoprotein-like domain BWK49_RS21335 2549572429ae3fa9357aeb588ca308ea 150 Gene3D G3DSA:3.40.50.360 8 140 1.4E-53 T 06-07-2017 IPR029039 Flavoprotein-like domain BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 SUPERFAMILY SSF47336 3495 3568 4.32E-19 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 Gene3D G3DSA:2.30.38.10 4364 4444 1.2E-24 T 06-07-2017 BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 Gene3D G3DSA:2.30.38.10 761 841 4.0E-25 T 06-07-2017 BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 Gene3D G3DSA:2.30.38.10 3311 3390 3.5E-23 T 06-07-2017 BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 Gene3D G3DSA:2.30.38.10 2251 2330 9.1E-22 T 06-07-2017 BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 SUPERFAMILY SSF52777 192 423 5.11E-20 T 06-07-2017 BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 SUPERFAMILY SSF52777 1679 1920 3.11E-56 T 06-07-2017 BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 SUPERFAMILY SSF52777 1030 1197 1.33E-24 T 06-07-2017 BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 SUPERFAMILY SSF52777 3779 4029 2.0E-55 T 06-07-2017 BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 SUPERFAMILY SSF56801 1910 2460 2.75E-140 T 06-07-2017 BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 Gene3D G3DSA:3.30.300.30 3395 3506 1.1E-32 T 06-07-2017 BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 Gene3D G3DSA:3.30.300.30 4449 4564 9.3E-34 T 06-07-2017 BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 Gene3D G3DSA:3.30.300.30 847 957 1.1E-36 T 06-07-2017 BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 Gene3D G3DSA:3.30.300.30 2335 2451 1.5E-35 T 06-07-2017 BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 SMART SM01294 3504 3568 1.3E-4 T 06-07-2017 BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 SUPERFAMILY SSF47336 4553 4626 6.41E-20 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 SUPERFAMILY SSF56801 4026 4574 7.59E-142 T 06-07-2017 BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 SUPERFAMILY SSF56801 423 967 1.44E-142 T 06-07-2017 BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 1338 1492 2.8E-31 T 06-07-2017 IPR010060 Non-ribosomal peptide synthase BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 ProSitePatterns PS00455 Putative AMP-binding domain signature. 604 615 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 Pfam PF00550 Phosphopantetheine attachment site 2450 2509 3.3E-13 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 Pfam PF00550 Phosphopantetheine attachment site 4566 4625 2.8E-14 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 Pfam PF00550 Phosphopantetheine attachment site 3506 3565 2.4E-12 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 Pfam PF00550 Phosphopantetheine attachment site 957 1016 4.8E-9 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 Pfam PF00668 Condensation domain 2531 2833 4.0E-60 T 06-07-2017 IPR001242 Condensation domain BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 Pfam PF00668 Condensation domain 1074 1323 2.6E-19 T 06-07-2017 IPR001242 Condensation domain BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 Pfam PF00668 Condensation domain 13 296 1.6E-24 T 06-07-2017 IPR001242 Condensation domain BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 Pfam PF00668 Condensation domain 1501 1791 1.4E-51 T 06-07-2017 IPR001242 Condensation domain BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 Pfam PF00668 Condensation domain 3585 3888 6.8E-63 T 06-07-2017 IPR001242 Condensation domain BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 SUPERFAMILY SSF47336 2439 2512 1.28E-19 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 SUPERFAMILY SSF52777 1498 1693 7.89E-37 T 06-07-2017 BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 SUPERFAMILY SSF52777 3589 3764 1.11E-46 T 06-07-2017 BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 Gene3D G3DSA:3.40.50.720 4677 4948 3.0E-27 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 SUPERFAMILY SSF51735 4676 5000 1.31E-30 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 ProSitePatterns PS00455 Putative AMP-binding domain signature. 4206 4217 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 ProSitePatterns PS00012 Phosphopantetheine attachment site. 4585 4600 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 Pfam PF00501 AMP-binding enzyme 3012 3400 3.1E-83 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 Pfam PF00501 AMP-binding enzyme 1953 2340 2.2E-80 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 Pfam PF00501 AMP-binding enzyme 462 851 1.2E-83 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 Pfam PF00501 AMP-binding enzyme 4067 4454 4.3E-86 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 SUPERFAMILY SSF52777 1211 1471 7.67E-28 T 06-07-2017 BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2471 2486 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 ProSitePatterns PS00455 Putative AMP-binding domain signature. 3150 3161 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 ProSitePatterns PS00012 Phosphopantetheine attachment site. 978 993 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 Pfam PF13193 AMP-binding enzyme C-terminal domain 3408 3479 1.5E-6 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 Pfam PF13193 AMP-binding enzyme C-terminal domain 4462 4537 2.1E-8 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 Pfam PF13193 AMP-binding enzyme C-terminal domain 2348 2423 4.5E-8 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 Pfam PF13193 AMP-binding enzyme C-terminal domain 859 930 4.6E-10 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 Gene3D G3DSA:3.40.50.980 457 612 3.6E-38 T 06-07-2017 BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 Gene3D G3DSA:3.40.50.980 1948 2101 4.4E-42 T 06-07-2017 BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 Gene3D G3DSA:3.40.50.980 3007 3159 2.0E-45 T 06-07-2017 BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 Gene3D G3DSA:3.40.50.980 4062 4215 2.1E-45 T 06-07-2017 BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 SUPERFAMILY SSF56801 2968 3510 3.92E-138 T 06-07-2017 BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 Gene3D G3DSA:3.40.50.980 2102 2250 1.1E-34 T 06-07-2017 BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 Gene3D G3DSA:3.40.50.980 613 755 3.2E-35 T 06-07-2017 BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 Gene3D G3DSA:3.40.50.980 4216 4355 7.1E-33 T 06-07-2017 BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 Gene3D G3DSA:3.40.50.980 3160 3310 5.8E-36 T 06-07-2017 BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 SUPERFAMILY SSF52777 14 182 7.78E-27 T 06-07-2017 BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 TIGRFAM TIGR01746 Thioester-redct: thioester reductase domain 4677 5078 1.8E-97 T 06-07-2017 IPR010080 Thioester reductase-like domain BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 Pfam PF07993 Male sterility protein 4680 4942 1.7E-56 T 06-07-2017 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3527 3542 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1974 2364 1.2E-120 T 06-07-2017 IPR010071 Amino acid adenylation domain BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 4088 4478 1.8E-125 T 06-07-2017 IPR010071 Amino acid adenylation domain BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 481 875 3.3E-121 T 06-07-2017 IPR010071 Amino acid adenylation domain BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 3033 3424 5.6E-127 T 06-07-2017 IPR010071 Amino acid adenylation domain BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 SMART SM00823 Phosphopantetheine attachment site 4561 4630 4.2E-9 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 SMART SM00823 Phosphopantetheine attachment site 2447 2516 4.0E-8 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 SMART SM00823 Phosphopantetheine attachment site 3503 3572 1.7E-6 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 SMART SM00823 Phosphopantetheine attachment site 954 1022 0.039 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2092 2103 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 SUPERFAMILY SSF52777 2721 2974 3.89E-57 T 06-07-2017 BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 SUPERFAMILY SSF47336 946 1016 5.76E-15 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 Gene3D G3DSA:1.10.1200.10 2452 2516 7.2E-26 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 Gene3D G3DSA:1.10.1200.10 3507 3571 2.1E-24 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 Gene3D G3DSA:1.10.1200.10 4565 4632 4.4E-27 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 Gene3D G3DSA:1.10.1200.10 958 1019 3.1E-23 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 Pfam PF13745 HxxPF-repeated domain 1821 1897 6.7E-7 T 06-07-2017 BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 Pfam PF13745 HxxPF-repeated domain 3910 4011 1.0E-24 T 06-07-2017 BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 Pfam PF13745 HxxPF-repeated domain 2855 2957 8.8E-26 T 06-07-2017 BWK49_RS22380 79be60a85c4f79a202541ff389085ff7 5082 SUPERFAMILY SSF52777 2533 2708 4.89E-46 T 06-07-2017 BWK49_RS03090 63e59fdf4ed77de444de22fad88e71f1 312 Hamap MF_00158 Pantothenate synthetase [panC]. 15 288 38.181 T 06-07-2017 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 BWK49_RS03090 63e59fdf4ed77de444de22fad88e71f1 312 Gene3D G3DSA:3.30.1300.10 189 293 3.7E-33 T 06-07-2017 BWK49_RS03090 63e59fdf4ed77de444de22fad88e71f1 312 SUPERFAMILY SSF52374 13 290 2.91E-103 T 06-07-2017 BWK49_RS03090 63e59fdf4ed77de444de22fad88e71f1 312 Gene3D G3DSA:3.40.50.620 13 188 1.2E-76 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold BWK49_RS03090 63e59fdf4ed77de444de22fad88e71f1 312 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 24 287 4.1E-84 T 06-07-2017 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 BWK49_RS03090 63e59fdf4ed77de444de22fad88e71f1 312 Pfam PF02569 Pantoate-beta-alanine ligase 21 286 8.6E-95 T 06-07-2017 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 BWK49_RS19980 8b9ea2232ba84758ef15591027815376 496 Pfam PF06039 Malate:quinone oxidoreductase (Mqo) 9 492 1.5E-205 T 06-07-2017 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 BWK49_RS19980 8b9ea2232ba84758ef15591027815376 496 Hamap MF_00212 Probable malate:quinone oxidoreductase [mqo]. 6 492 49.885 T 06-07-2017 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 BWK49_RS19980 8b9ea2232ba84758ef15591027815376 496 TIGRFAM TIGR01320 mal_quin_oxido: malate dehydrogenase (acceptor) 10 490 2.8E-235 T 06-07-2017 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 BWK49_RS19980 8b9ea2232ba84758ef15591027815376 496 SUPERFAMILY SSF51905 6 326 8.58E-23 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS19980 8b9ea2232ba84758ef15591027815376 496 Gene3D G3DSA:3.50.50.60 10 76 1.8E-19 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS19980 8b9ea2232ba84758ef15591027815376 496 Gene3D G3DSA:3.50.50.60 150 335 1.8E-19 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS04020 02361a2e381b6c40591028235571057e 486 Pfam PF02127 Aminopeptidase I zinc metalloprotease (M18) 71 482 1.3E-139 T 06-07-2017 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 BWK49_RS04020 02361a2e381b6c40591028235571057e 486 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 130 146 7.3E-50 T 06-07-2017 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 BWK49_RS04020 02361a2e381b6c40591028235571057e 486 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 201 218 7.3E-50 T 06-07-2017 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 BWK49_RS04020 02361a2e381b6c40591028235571057e 486 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 318 336 7.3E-50 T 06-07-2017 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 BWK49_RS04020 02361a2e381b6c40591028235571057e 486 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 450 465 7.3E-50 T 06-07-2017 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 BWK49_RS04020 02361a2e381b6c40591028235571057e 486 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 163 183 7.3E-50 T 06-07-2017 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 BWK49_RS04020 02361a2e381b6c40591028235571057e 486 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 361 377 7.3E-50 T 06-07-2017 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 BWK49_RS04020 02361a2e381b6c40591028235571057e 486 Gene3D G3DSA:2.30.250.10 141 270 6.1E-33 T 06-07-2017 IPR023358 Peptidase M18, domain 2 GO:0004177 BWK49_RS04020 02361a2e381b6c40591028235571057e 486 SUPERFAMILY SSF53187 60 141 5.8E-92 T 06-07-2017 BWK49_RS04020 02361a2e381b6c40591028235571057e 486 SUPERFAMILY SSF53187 264 483 5.8E-92 T 06-07-2017 BWK49_RS04020 02361a2e381b6c40591028235571057e 486 Gene3D G3DSA:3.40.630.10 64 140 1.5E-95 T 06-07-2017 BWK49_RS04020 02361a2e381b6c40591028235571057e 486 Gene3D G3DSA:3.40.630.10 277 483 1.5E-95 T 06-07-2017 BWK49_RS04020 02361a2e381b6c40591028235571057e 486 Hamap MF_00467 Probable M18 family aminopeptidase 2 [apeB]. 51 485 55.243 T 06-07-2017 IPR022984 M18 family aminopeptidase 2, putative GO:0004177 BWK49_RS04020 02361a2e381b6c40591028235571057e 486 SUPERFAMILY SSF101821 142 263 2.75E-24 T 06-07-2017 BWK49_RS11055 af7150ba304f98f0168d98f6fe9525e2 415 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 239 395 4.6E-13 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS11055 af7150ba304f98f0168d98f6fe9525e2 415 SUPERFAMILY SSF47203 239 397 7.23E-12 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS11055 af7150ba304f98f0168d98f6fe9525e2 415 SUPERFAMILY SSF56645 39 251 1.1E-57 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS11055 af7150ba304f98f0168d98f6fe9525e2 415 Gene3D G3DSA:2.40.110.10 132 228 1.9E-34 T 06-07-2017 BWK49_RS11055 af7150ba304f98f0168d98f6fe9525e2 415 Gene3D G3DSA:1.10.540.10 17 129 4.1E-11 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS11055 af7150ba304f98f0168d98f6fe9525e2 415 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 17 129 3.7E-11 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS11055 af7150ba304f98f0168d98f6fe9525e2 415 Gene3D G3DSA:1.20.140.10 229 401 7.8E-17 T 06-07-2017 BWK49_RS11055 af7150ba304f98f0168d98f6fe9525e2 415 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 133 216 7.4E-20 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 BWK49_RS13370 04ebbd424301f600d33ff8906acdfaee 281 Gene3D G3DSA:3.40.50.150 71 271 4.8E-67 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS13370 04ebbd424301f600d33ff8906acdfaee 281 Pfam PF14801 tRNA methyltransferase complex GCD14 subunit N-term 4 54 7.5E-26 T 06-07-2017 BWK49_RS13370 04ebbd424301f600d33ff8906acdfaee 281 SUPERFAMILY SSF53335 7 261 5.95E-74 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS13370 04ebbd424301f600d33ff8906acdfaee 281 Pfam PF08704 tRNA methyltransferase complex GCD14 subunit 73 238 3.1E-20 T 06-07-2017 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829 BWK49_RS13370 04ebbd424301f600d33ff8906acdfaee 281 Gene3D G3DSA:3.10.330.20 4 67 1.1E-29 T 06-07-2017 BWK49_RS13370 04ebbd424301f600d33ff8906acdfaee 281 PIRSF PIRSF017269 1 271 2.9E-88 T 06-07-2017 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829 BWK49_RS21635 05a08261177a3c8d205fd1899b1d0f5d 208 Gene3D G3DSA:3.40.630.30 21 198 1.8E-44 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase BWK49_RS21635 05a08261177a3c8d205fd1899b1d0f5d 208 SMART SM01006 37 84 4.2E-12 T 06-07-2017 IPR019432 Siderophore biosynthesis protein, conserved domain BWK49_RS21635 05a08261177a3c8d205fd1899b1d0f5d 208 SUPERFAMILY SSF55729 6 197 9.07E-48 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase BWK49_RS21635 05a08261177a3c8d205fd1899b1d0f5d 208 Pfam PF13523 Acetyltransferase (GNAT) domain 41 185 1.0E-40 T 06-07-2017 BWK49_RS27460 50634ed13a2ac21d6c1135d26684ac31 287 SUPERFAMILY SSF51735 1 244 2.28E-63 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS27460 50634ed13a2ac21d6c1135d26684ac31 287 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 144 152 2.9E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27460 50634ed13a2ac21d6c1135d26684ac31 287 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 164 183 2.9E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27460 50634ed13a2ac21d6c1135d26684ac31 287 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 91 102 2.9E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27460 50634ed13a2ac21d6c1135d26684ac31 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 91 102 5.3E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27460 50634ed13a2ac21d6c1135d26684ac31 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 5.3E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27460 50634ed13a2ac21d6c1135d26684ac31 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 183 5.3E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27460 50634ed13a2ac21d6c1135d26684ac31 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 138 154 5.3E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27460 50634ed13a2ac21d6c1135d26684ac31 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 5.3E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27460 50634ed13a2ac21d6c1135d26684ac31 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 185 202 5.3E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27460 50634ed13a2ac21d6c1135d26684ac31 287 Gene3D G3DSA:3.40.50.720 4 245 7.3E-64 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS27460 50634ed13a2ac21d6c1135d26684ac31 287 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 203 2.4E-5 T 06-07-2017 BWK49_RS27460 50634ed13a2ac21d6c1135d26684ac31 287 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 151 179 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS27460 50634ed13a2ac21d6c1135d26684ac31 287 Pfam PF00106 short chain dehydrogenase 8 203 8.9E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS18505 6678b0735a3e6494566ad391c47a0076 179 SUPERFAMILY SSF55729 6 176 1.31E-35 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase BWK49_RS18505 6678b0735a3e6494566ad391c47a0076 179 Gene3D G3DSA:3.40.630.30 4 176 3.2E-39 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase BWK49_RS18505 6678b0735a3e6494566ad391c47a0076 179 Pfam PF13302 Acetyltransferase (GNAT) domain 13 149 6.6E-27 T 06-07-2017 IPR000182 GNAT domain GO:0008080 BWK49_RS18140 5975b1714a72a3f9cf643326aa96957d 166 TIGRFAM TIGR01994 SUF_scaf_2: SUF system FeS assembly protein, NifU family 5 143 5.8E-49 T 06-07-2017 BWK49_RS18140 5975b1714a72a3f9cf643326aa96957d 166 Gene3D G3DSA:3.90.1010.10 7 155 2.1E-42 T 06-07-2017 BWK49_RS18140 5975b1714a72a3f9cf643326aa96957d 166 Pfam PF01592 NifU-like N terminal domain 8 131 1.0E-32 T 06-07-2017 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 BWK49_RS18140 5975b1714a72a3f9cf643326aa96957d 166 SUPERFAMILY SSF82649 3 148 1.52E-43 T 06-07-2017 BWK49_RS24585 2bab14e033e4fbc030fa9e8d4f2bde6e 142 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 38 70 1.0E-13 T 06-07-2017 BWK49_RS24585 2bab14e033e4fbc030fa9e8d4f2bde6e 142 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 5 142 1.6E-63 T 06-07-2017 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS24585 2bab14e033e4fbc030fa9e8d4f2bde6e 142 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 7 142 30.489 T 06-07-2017 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 BWK49_RS24585 2bab14e033e4fbc030fa9e8d4f2bde6e 142 Gene3D G3DSA:1.10.10.250 74 142 1.3E-31 T 06-07-2017 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 BWK49_RS24585 2bab14e033e4fbc030fa9e8d4f2bde6e 142 SUPERFAMILY SSF46906 69 142 6.15E-26 T 06-07-2017 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 BWK49_RS24585 2bab14e033e4fbc030fa9e8d4f2bde6e 142 Pfam PF00298 Ribosomal protein L11, RNA binding domain 73 141 8.8E-26 T 06-07-2017 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 BWK49_RS24585 2bab14e033e4fbc030fa9e8d4f2bde6e 142 ProSitePatterns PS00359 Ribosomal protein L11 signature. 128 142 - T 06-07-2017 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 BWK49_RS24585 2bab14e033e4fbc030fa9e8d4f2bde6e 142 Pfam PF03946 Ribosomal protein L11, N-terminal domain 11 68 1.4E-29 T 06-07-2017 IPR020784 Ribosomal protein L11, N-terminal BWK49_RS24585 2bab14e033e4fbc030fa9e8d4f2bde6e 142 SUPERFAMILY SSF54747 4 74 6.15E-30 T 06-07-2017 IPR020784 Ribosomal protein L11, N-terminal BWK49_RS24585 2bab14e033e4fbc030fa9e8d4f2bde6e 142 SMART SM00649 11 142 2.2E-84 T 06-07-2017 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 BWK49_RS24585 2bab14e033e4fbc030fa9e8d4f2bde6e 142 Gene3D G3DSA:3.30.1550.10 4 73 1.2E-38 T 06-07-2017 IPR020784 Ribosomal protein L11, N-terminal BWK49_RS11885 ea38b348f9b2e05a745f29ecac7db06b 507 Pfam PF00171 Aldehyde dehydrogenase family 12 459 1.9E-136 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 BWK49_RS11885 ea38b348f9b2e05a745f29ecac7db06b 507 Pfam PF00171 Aldehyde dehydrogenase family 473 504 6.5E-7 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 BWK49_RS11885 ea38b348f9b2e05a745f29ecac7db06b 507 SUPERFAMILY SSF53720 2 505 6.54E-142 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 BWK49_RS11885 ea38b348f9b2e05a745f29ecac7db06b 507 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 255 262 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 BWK49_RS11885 ea38b348f9b2e05a745f29ecac7db06b 507 Gene3D G3DSA:3.40.605.10 2 264 6.1E-79 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 BWK49_RS11885 ea38b348f9b2e05a745f29ecac7db06b 507 Gene3D G3DSA:3.40.309.10 265 444 1.3E-56 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 BWK49_RS26005 e725a202e82382822dee47c0dd05ad28 432 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 132 143 - T 06-07-2017 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 BWK49_RS26005 e725a202e82382822dee47c0dd05ad28 432 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 06-07-2017 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 BWK49_RS26005 e725a202e82382822dee47c0dd05ad28 432 Pfam PF00709 Adenylosuccinate synthetase 4 422 7.3E-172 T 06-07-2017 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 BWK49_RS26005 e725a202e82382822dee47c0dd05ad28 432 Gene3D G3DSA:3.90.170.10 267 424 1.1E-69 T 06-07-2017 BWK49_RS26005 e725a202e82382822dee47c0dd05ad28 432 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 432 201.726 T 06-07-2017 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 BWK49_RS26005 e725a202e82382822dee47c0dd05ad28 432 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 5 427 1.1E-165 T 06-07-2017 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 BWK49_RS26005 e725a202e82382822dee47c0dd05ad28 432 SUPERFAMILY SSF52540 1 428 5.52E-170 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS26005 e725a202e82382822dee47c0dd05ad28 432 Gene3D G3DSA:3.40.440.10 194 265 1.9E-64 T 06-07-2017 BWK49_RS26005 e725a202e82382822dee47c0dd05ad28 432 Gene3D G3DSA:3.40.440.10 2 94 1.9E-64 T 06-07-2017 BWK49_RS26005 e725a202e82382822dee47c0dd05ad28 432 SMART SM00788 3 423 2.2E-276 T 06-07-2017 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 BWK49_RS26005 e725a202e82382822dee47c0dd05ad28 432 Gene3D G3DSA:1.10.300.10 102 193 5.6E-33 T 06-07-2017 BWK49_RS22510 78c7314cff2b34e18b26f2f53f9dcfeb 487 SUPERFAMILY SSF53720 8 476 6.94E-150 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 BWK49_RS22510 78c7314cff2b34e18b26f2f53f9dcfeb 487 Pfam PF00171 Aldehyde dehydrogenase family 24 474 2.7E-154 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 BWK49_RS22510 78c7314cff2b34e18b26f2f53f9dcfeb 487 Gene3D G3DSA:3.40.309.10 264 441 1.5E-65 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 BWK49_RS22510 78c7314cff2b34e18b26f2f53f9dcfeb 487 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 250 257 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 BWK49_RS22510 78c7314cff2b34e18b26f2f53f9dcfeb 487 Gene3D G3DSA:3.40.605.10 9 263 5.7E-79 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 BWK49_RS28560 66b89572a63e11f27c54dff43b36c687 202 PIRSF PIRSF009320 1 186 8.7E-32 T 06-07-2017 BWK49_RS28560 66b89572a63e11f27c54dff43b36c687 202 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 6 145 8.0E-15 T 06-07-2017 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain BWK49_RS28560 66b89572a63e11f27c54dff43b36c687 202 Gene3D G3DSA:3.40.50.300 2 195 1.8E-23 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS28560 66b89572a63e11f27c54dff43b36c687 202 SUPERFAMILY SSF52540 2 191 9.3E-24 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS01630 006bbf3151c911a4b7450b54ea02e9fe 435 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 48 63 2.5E-52 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS01630 006bbf3151c911a4b7450b54ea02e9fe 435 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 133 159 2.5E-52 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS01630 006bbf3151c911a4b7450b54ea02e9fe 435 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 18 43 2.5E-52 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS01630 006bbf3151c911a4b7450b54ea02e9fe 435 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 90 110 2.5E-52 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS01630 006bbf3151c911a4b7450b54ea02e9fe 435 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 69 89 2.5E-52 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS01630 006bbf3151c911a4b7450b54ea02e9fe 435 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 176 198 2.5E-52 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS01630 006bbf3151c911a4b7450b54ea02e9fe 435 Gene3D G3DSA:3.90.380.10 138 433 1.4E-75 T 06-07-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 BWK49_RS01630 006bbf3151c911a4b7450b54ea02e9fe 435 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 185 432 2.5E-19 T 06-07-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 BWK49_RS01630 006bbf3151c911a4b7450b54ea02e9fe 435 SUPERFAMILY SSF55961 151 433 5.34E-46 T 06-07-2017 BWK49_RS01630 006bbf3151c911a4b7450b54ea02e9fe 435 SUPERFAMILY SSF50022 8 148 2.49E-45 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS01630 006bbf3151c911a4b7450b54ea02e9fe 435 ProSitePatterns PS00570 Bacterial ring hydroxylating dioxygenases alpha-subunit signature. 76 99 - T 06-07-2017 IPR015881 Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site GO:0005506|GO:0016705|GO:0051537|GO:0055114 BWK49_RS01630 006bbf3151c911a4b7450b54ea02e9fe 435 Pfam PF00355 Rieske [2Fe-2S] domain 33 114 5.4E-18 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS01630 006bbf3151c911a4b7450b54ea02e9fe 435 Gene3D G3DSA:2.102.10.10 33 137 6.8E-20 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS05905 0ff21c0cbc9ba55a0a39c12a92ca89a5 574 Gene3D G3DSA:3.30.9.10 335 363 1.8E-13 T 06-07-2017 BWK49_RS05905 0ff21c0cbc9ba55a0a39c12a92ca89a5 574 Gene3D G3DSA:3.30.9.10 178 280 1.8E-13 T 06-07-2017 BWK49_RS05905 0ff21c0cbc9ba55a0a39c12a92ca89a5 574 Hamap MF_01652 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase [mhpA]. 3 560 65.225 T 06-07-2017 IPR023786 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase GO:0008688|GO:0019622|GO:0055114 KEGG: 00360+1.14.13.127|KEGG: 00362+1.14.13.12|KEGG: 00627+1.14.13.12|MetaCyc: PWY-6690 BWK49_RS05905 0ff21c0cbc9ba55a0a39c12a92ca89a5 574 Pfam PF01494 FAD binding domain 12 352 2.1E-78 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 BWK49_RS05905 0ff21c0cbc9ba55a0a39c12a92ca89a5 574 Gene3D G3DSA:3.50.50.60 7 177 2.8E-47 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS05905 0ff21c0cbc9ba55a0a39c12a92ca89a5 574 Gene3D G3DSA:3.50.50.60 285 325 2.8E-47 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS05905 0ff21c0cbc9ba55a0a39c12a92ca89a5 574 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 166 181 3.9E-40 T 06-07-2017 BWK49_RS05905 0ff21c0cbc9ba55a0a39c12a92ca89a5 574 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 287 302 3.9E-40 T 06-07-2017 BWK49_RS05905 0ff21c0cbc9ba55a0a39c12a92ca89a5 574 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 14 36 3.9E-40 T 06-07-2017 BWK49_RS05905 0ff21c0cbc9ba55a0a39c12a92ca89a5 574 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 320 338 3.9E-40 T 06-07-2017 BWK49_RS05905 0ff21c0cbc9ba55a0a39c12a92ca89a5 574 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 338 354 3.9E-40 T 06-07-2017 BWK49_RS05905 0ff21c0cbc9ba55a0a39c12a92ca89a5 574 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 302 318 3.9E-40 T 06-07-2017 BWK49_RS05905 0ff21c0cbc9ba55a0a39c12a92ca89a5 574 SUPERFAMILY SSF51905 12 187 4.09E-64 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS05905 0ff21c0cbc9ba55a0a39c12a92ca89a5 574 SUPERFAMILY SSF51905 274 388 4.09E-64 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS03195 513c076ff6bc931a693b0a25d9ab1410 304 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 32 284 3.2E-39 T 06-07-2017 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 BWK49_RS03195 513c076ff6bc931a693b0a25d9ab1410 304 Gene3D G3DSA:3.20.20.190 23 301 1.7E-80 T 06-07-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 BWK49_RS03195 513c076ff6bc931a693b0a25d9ab1410 304 SUPERFAMILY SSF51695 27 290 8.63E-62 T 06-07-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 BWK49_RS08095 6dc0eb4f0e3e564e406f1da423cfa184 329 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 1.6E-18 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS08095 6dc0eb4f0e3e564e406f1da423cfa184 329 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 1.6E-18 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS08095 6dc0eb4f0e3e564e406f1da423cfa184 329 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 1.6E-18 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS08095 6dc0eb4f0e3e564e406f1da423cfa184 329 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 1.6E-18 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS08095 6dc0eb4f0e3e564e406f1da423cfa184 329 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 1.6E-18 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS08095 6dc0eb4f0e3e564e406f1da423cfa184 329 Pfam PF00106 short chain dehydrogenase 6 196 1.9E-43 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS08095 6dc0eb4f0e3e564e406f1da423cfa184 329 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS08095 6dc0eb4f0e3e564e406f1da423cfa184 329 SUPERFAMILY SSF51735 4 254 2.75E-58 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS08095 6dc0eb4f0e3e564e406f1da423cfa184 329 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5 188 5.8E-4 T 06-07-2017 BWK49_RS08095 6dc0eb4f0e3e564e406f1da423cfa184 329 Gene3D G3DSA:3.40.50.720 5 260 4.0E-61 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS14260 bd340aa9efb1cd04814d801d76b820e5 206 ProSitePatterns PS00155 Cutinase, serine active site. 94 106 - T 06-07-2017 IPR011150 Cutinase, monofunctional GO:0005576|GO:0050525 BWK49_RS14260 bd340aa9efb1cd04814d801d76b820e5 206 Pfam PF01083 Cutinase 20 198 3.9E-60 T 06-07-2017 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 BWK49_RS14260 bd340aa9efb1cd04814d801d76b820e5 206 Gene3D G3DSA:3.40.50.1820 12 201 4.8E-56 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS14260 bd340aa9efb1cd04814d801d76b820e5 206 ProSitePatterns PS00931 Cutinase, aspartate and histidine active sites. 163 179 - T 06-07-2017 IPR011150 Cutinase, monofunctional GO:0005576|GO:0050525 BWK49_RS14260 bd340aa9efb1cd04814d801d76b820e5 206 SMART SM01110 19 199 5.4E-92 T 06-07-2017 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 BWK49_RS14260 bd340aa9efb1cd04814d801d76b820e5 206 SUPERFAMILY SSF53474 12 200 3.08E-43 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS08625 a14a5f1e6574f5298e7e2479df2aa577 283 SUPERFAMILY SSF51735 3 255 3.36E-62 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS08625 a14a5f1e6574f5298e7e2479df2aa577 283 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 193 0.0015 T 06-07-2017 BWK49_RS08625 a14a5f1e6574f5298e7e2479df2aa577 283 Pfam PF00106 short chain dehydrogenase 7 198 1.4E-49 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS08625 a14a5f1e6574f5298e7e2479df2aa577 283 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS08625 a14a5f1e6574f5298e7e2479df2aa577 283 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 9.2E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS08625 a14a5f1e6574f5298e7e2479df2aa577 283 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 9.2E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS08625 a14a5f1e6574f5298e7e2479df2aa577 283 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 9.2E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS08625 a14a5f1e6574f5298e7e2479df2aa577 283 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 5.1E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS08625 a14a5f1e6574f5298e7e2479df2aa577 283 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 5.1E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS08625 a14a5f1e6574f5298e7e2479df2aa577 283 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 5.1E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS08625 a14a5f1e6574f5298e7e2479df2aa577 283 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 5.1E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS08625 a14a5f1e6574f5298e7e2479df2aa577 283 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 5.1E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS08625 a14a5f1e6574f5298e7e2479df2aa577 283 Gene3D G3DSA:3.40.50.720 5 237 9.3E-62 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS08540 3989d5236b27fabb94fb5ca847b118a8 139 TIGRFAM TIGR01410 tatB: twin arginine-targeting protein translocase TatB 4 84 1.3E-25 T 06-07-2017 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 BWK49_RS08540 3989d5236b27fabb94fb5ca847b118a8 139 Pfam PF02416 mttA/Hcf106 family 5 39 2.8E-4 T 06-07-2017 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 BWK49_RS08540 3989d5236b27fabb94fb5ca847b118a8 139 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 2 22 4.6E-12 T 06-07-2017 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 BWK49_RS08540 3989d5236b27fabb94fb5ca847b118a8 139 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 41 59 4.6E-12 T 06-07-2017 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 BWK49_RS08540 3989d5236b27fabb94fb5ca847b118a8 139 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 22 41 4.6E-12 T 06-07-2017 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 BWK49_RS08540 3989d5236b27fabb94fb5ca847b118a8 139 Hamap MF_00237 Sec-independent protein translocase protein TatB [tatB]. 2 133 15.062 T 06-07-2017 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 BWK49_RS19600 f9f821cb1169673f3dbcefa4d332da50 388 Gene3D G3DSA:3.40.50.2000 1 212 1.8E-16 T 06-07-2017 BWK49_RS19600 f9f821cb1169673f3dbcefa4d332da50 388 Gene3D G3DSA:3.40.50.2000 270 367 6.4E-17 T 06-07-2017 BWK49_RS19600 f9f821cb1169673f3dbcefa4d332da50 388 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 285 374 4.2E-6 T 06-07-2017 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 BWK49_RS19600 f9f821cb1169673f3dbcefa4d332da50 388 SUPERFAMILY SSF53756 1 381 1.35E-59 T 06-07-2017 BWK49_RS02820 052991cd7ff20fe4d09246e9f4845c6c 232 Gene3D G3DSA:2.40.10.10 37 112 1.9E-5 T 06-07-2017 BWK49_RS02820 052991cd7ff20fe4d09246e9f4845c6c 232 Gene3D G3DSA:2.40.10.10 127 201 2.5E-11 T 06-07-2017 BWK49_RS02820 052991cd7ff20fe4d09246e9f4845c6c 232 SUPERFAMILY SSF50494 40 202 1.92E-23 T 06-07-2017 IPR009003 Peptidase S1, PA clan BWK49_RS18355 80145a11911dbfb521a7b59ff9e96f1d 199 PIRSF PIRSF000498 1 199 5.2E-69 T 06-07-2017 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 BWK49_RS18355 80145a11911dbfb521a7b59ff9e96f1d 199 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 198 1.0E-59 T 06-07-2017 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 BWK49_RS18355 80145a11911dbfb521a7b59ff9e96f1d 199 SUPERFAMILY SSF63380 1 88 1.62E-22 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 BWK49_RS18355 80145a11911dbfb521a7b59ff9e96f1d 199 Gene3D G3DSA:2.40.30.20 5 104 7.2E-30 T 06-07-2017 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 BWK49_RS18355 80145a11911dbfb521a7b59ff9e96f1d 199 Gene3D G3DSA:2.40.30.20 105 197 1.3E-29 T 06-07-2017 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 BWK49_RS18355 80145a11911dbfb521a7b59ff9e96f1d 199 SUPERFAMILY SSF63380 93 198 3.15E-31 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 BWK49_RS18355 80145a11911dbfb521a7b59ff9e96f1d 199 Pfam PF00677 Lumazine binding domain 100 187 4.1E-22 T 06-07-2017 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 BWK49_RS18355 80145a11911dbfb521a7b59ff9e96f1d 199 Pfam PF00677 Lumazine binding domain 3 87 3.1E-22 T 06-07-2017 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 BWK49_RS26875 505b39222e42e62c0e637b6272a25406 228 SUPERFAMILY SSF46689 4 85 3.44E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS26875 505b39222e42e62c0e637b6272a25406 228 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 60 1.6E-13 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS26875 505b39222e42e62c0e637b6272a25406 228 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 1.8E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS26875 505b39222e42e62c0e637b6272a25406 228 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 1.8E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS26875 505b39222e42e62c0e637b6272a25406 228 Gene3D G3DSA:1.10.357.10 12 213 7.8E-32 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS26875 505b39222e42e62c0e637b6272a25406 228 ProSitePatterns PS01081 TetR-type HTH domain signature. 29 59 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site BWK49_RS26875 505b39222e42e62c0e637b6272a25406 228 SUPERFAMILY SSF48498 88 168 1.81E-6 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS21275 49deac344864f74ccbfcee971af93df6 411 TIGRFAM TIGR00338 serB: phosphoserine phosphatase SerB 168 386 4.7E-74 T 06-07-2017 BWK49_RS21275 49deac344864f74ccbfcee971af93df6 411 Pfam PF12710 haloacid dehalogenase-like hydrolase 184 351 6.0E-30 T 06-07-2017 BWK49_RS21275 49deac344864f74ccbfcee971af93df6 411 Gene3D G3DSA:1.10.150.210 193 244 1.3E-23 T 06-07-2017 IPR023190 Phosphoserine phosphatase, domain 2 GO:0004647|GO:0006564 KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3|Reactome: R-HSA-977347 BWK49_RS21275 49deac344864f74ccbfcee971af93df6 411 Gene3D G3DSA:3.30.70.260 9 87 9.4E-17 T 06-07-2017 BWK49_RS21275 49deac344864f74ccbfcee971af93df6 411 Gene3D G3DSA:3.30.70.260 110 183 8.8E-6 T 06-07-2017 BWK49_RS21275 49deac344864f74ccbfcee971af93df6 411 Gene3D G3DSA:3.40.50.1000 245 373 4.7E-48 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS21275 49deac344864f74ccbfcee971af93df6 411 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 183 353 3.5E-30 T 06-07-2017 IPR006383 HAD-superfamily hydrolase, subfamily IB, PSPase-like GO:0008152|GO:0016791 BWK49_RS21275 49deac344864f74ccbfcee971af93df6 411 Pfam PF13740 ACT domain 9 82 1.3E-16 T 06-07-2017 BWK49_RS21275 49deac344864f74ccbfcee971af93df6 411 SUPERFAMILY SSF56784 181 389 3.47E-51 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS21275 49deac344864f74ccbfcee971af93df6 411 SUPERFAMILY SSF55021 9 87 1.52E-9 T 06-07-2017 BWK49_RS00510 ebf803a9ce2dfbbd723b27531dff5605 193 SUPERFAMILY SSF46689 4 85 4.98E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS00510 ebf803a9ce2dfbbd723b27531dff5605 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 1.9E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS00510 ebf803a9ce2dfbbd723b27531dff5605 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 1.9E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS00510 ebf803a9ce2dfbbd723b27531dff5605 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 1.5E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS00510 ebf803a9ce2dfbbd723b27531dff5605 193 Gene3D G3DSA:1.10.357.10 12 188 4.5E-25 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS23095 667bdabe38ee97ef554587fa125f2a2b 377 PIRSF PIRSF002756 9 376 8.3E-71 T 06-07-2017 IPR005673 ABC transporter, phosphate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 BWK49_RS23095 667bdabe38ee97ef554587fa125f2a2b 377 Gene3D G3DSA:3.40.190.10 212 373 2.5E-17 T 06-07-2017 BWK49_RS23095 667bdabe38ee97ef554587fa125f2a2b 377 Pfam PF12849 PBP superfamily domain 48 345 8.3E-43 T 06-07-2017 IPR024370 PBP domain BWK49_RS23095 667bdabe38ee97ef554587fa125f2a2b 377 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 56 375 9.2E-109 T 06-07-2017 IPR005673 ABC transporter, phosphate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 BWK49_RS23095 667bdabe38ee97ef554587fa125f2a2b 377 Gene3D G3DSA:3.40.190.10 54 198 2.4E-52 T 06-07-2017 BWK49_RS23095 667bdabe38ee97ef554587fa125f2a2b 377 SUPERFAMILY SSF53850 46 372 4.89E-70 T 06-07-2017 BWK49_RS19320 69e49215efa8e6981ec0d1e006f8dd23 641 Gene3D G3DSA:3.40.50.970 2 187 6.0E-49 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS19320 69e49215efa8e6981ec0d1e006f8dd23 641 Gene3D G3DSA:3.40.50.970 235 292 6.0E-49 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS19320 69e49215efa8e6981ec0d1e006f8dd23 641 Gene3D G3DSA:3.40.50.970 293 478 1.4E-54 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS19320 69e49215efa8e6981ec0d1e006f8dd23 641 Pfam PF02779 Transketolase, pyrimidine binding domain 316 476 1.7E-36 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain BWK49_RS19320 69e49215efa8e6981ec0d1e006f8dd23 641 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 2 278 5.0E-107 T 06-07-2017 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 BWK49_RS19320 69e49215efa8e6981ec0d1e006f8dd23 641 ProSitePatterns PS00802 Transketolase signature 2. 420 436 - T 06-07-2017 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 BWK49_RS19320 69e49215efa8e6981ec0d1e006f8dd23 641 SUPERFAMILY SSF52518 2 191 3.08E-66 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS19320 69e49215efa8e6981ec0d1e006f8dd23 641 SUPERFAMILY SSF52518 239 376 3.08E-66 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS19320 69e49215efa8e6981ec0d1e006f8dd23 641 SUPERFAMILY SSF52922 505 624 1.83E-22 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 BWK49_RS19320 69e49215efa8e6981ec0d1e006f8dd23 641 Gene3D G3DSA:3.40.50.920 505 624 3.2E-27 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 BWK49_RS19320 69e49215efa8e6981ec0d1e006f8dd23 641 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 1 625 41.127 T 06-07-2017 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 BWK49_RS19320 69e49215efa8e6981ec0d1e006f8dd23 641 ProSitePatterns PS00801 Transketolase signature 1. 27 46 - T 06-07-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 BWK49_RS19320 69e49215efa8e6981ec0d1e006f8dd23 641 SMART SM00861 314 478 1.3E-52 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain BWK49_RS19320 69e49215efa8e6981ec0d1e006f8dd23 641 Pfam PF02780 Transketolase, C-terminal domain 504 616 6.1E-26 T 06-07-2017 IPR033248 Transketolase, C-terminal domain BWK49_RS19320 69e49215efa8e6981ec0d1e006f8dd23 641 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 4 624 1.2E-185 T 06-07-2017 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 BWK49_RS12145 720f5b7dea21bfeebdd4e0f7ac5150ce 292 Pfam PF00296 Luciferase-like monooxygenase 18 251 8.7E-47 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS12145 720f5b7dea21bfeebdd4e0f7ac5150ce 292 Gene3D G3DSA:3.20.20.30 19 283 8.0E-62 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS12145 720f5b7dea21bfeebdd4e0f7ac5150ce 292 SUPERFAMILY SSF51679 16 283 1.62E-57 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS12145 720f5b7dea21bfeebdd4e0f7ac5150ce 292 TIGRFAM TIGR03619 F420_Rv2161c: probable F420-dependent oxidoreductase, Rv2161c family 35 215 3.1E-67 T 06-07-2017 IPR019921 Luciferase-like, F420-dependent oxidoreductase, Rv2161c, predicted BWK49_RS22370 f815df6388ce3740b8515705c22c9e72 291 Pfam PF00106 short chain dehydrogenase 16 209 2.6E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS22370 f815df6388ce3740b8515705c22c9e72 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 1.0E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS22370 f815df6388ce3740b8515705c22c9e72 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 188 205 1.0E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS22370 f815df6388ce3740b8515705c22c9e72 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 1.0E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS22370 f815df6388ce3740b8515705c22c9e72 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 16 33 1.0E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS22370 f815df6388ce3740b8515705c22c9e72 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 184 1.0E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS22370 f815df6388ce3740b8515705c22c9e72 291 Gene3D G3DSA:3.40.50.720 12 241 1.7E-50 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS22370 f815df6388ce3740b8515705c22c9e72 291 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 1.3E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS22370 f815df6388ce3740b8515705c22c9e72 291 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 1.3E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS22370 f815df6388ce3740b8515705c22c9e72 291 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 165 184 1.3E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS22370 f815df6388ce3740b8515705c22c9e72 291 SUPERFAMILY SSF51735 11 242 8.78E-48 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS01295 8f883ff6bde7a42938da46d27413b9b6 328 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 87 1.8E-10 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 BWK49_RS01295 8f883ff6bde7a42938da46d27413b9b6 328 Gene3D G3DSA:3.40.50.720 147 262 1.4E-30 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS01295 8f883ff6bde7a42938da46d27413b9b6 328 SMART SM00829 10 326 7.0E-41 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 BWK49_RS01295 8f883ff6bde7a42938da46d27413b9b6 328 TIGRFAM TIGR02824 quinone_pig3: putative NAD(P)H quinone oxidoreductase, PIG3 family 4 328 4.2E-134 T 06-07-2017 IPR014189 Quinone oxidoreductase PIG3 Reactome: R-HSA-6803205 BWK49_RS01295 8f883ff6bde7a42938da46d27413b9b6 328 SUPERFAMILY SSF50129 4 138 5.82E-35 T 06-07-2017 IPR011032 GroES-like BWK49_RS01295 8f883ff6bde7a42938da46d27413b9b6 328 Gene3D G3DSA:3.90.180.10 3 146 3.6E-44 T 06-07-2017 IPR011032 GroES-like BWK49_RS01295 8f883ff6bde7a42938da46d27413b9b6 328 SUPERFAMILY SSF51735 111 269 5.68E-45 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS01295 8f883ff6bde7a42938da46d27413b9b6 328 Pfam PF00107 Zinc-binding dehydrogenase 151 266 2.7E-31 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 BWK49_RS15285 6a8e9d88cde7e80a4d4d64057e577889 408 Pfam PF00823 PPE family 6 162 5.4E-63 T 06-07-2017 IPR000030 PPE family BWK49_RS15285 6a8e9d88cde7e80a4d4d64057e577889 408 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 320 404 8.9E-17 T 06-07-2017 IPR022171 PPE family, C-terminal BWK49_RS15285 6a8e9d88cde7e80a4d4d64057e577889 408 SUPERFAMILY SSF140459 3 174 7.32E-65 T 06-07-2017 BWK49_RS20130 57065ea1e2a4d0d8ad8feebae240bc90 240 Gene3D G3DSA:1.10.10.10 122 218 2.2E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS20130 57065ea1e2a4d0d8ad8feebae240bc90 240 SMART SM00862 145 219 1.8E-19 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 BWK49_RS20130 57065ea1e2a4d0d8ad8feebae240bc90 240 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 218 2.7E-21 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 BWK49_RS20130 57065ea1e2a4d0d8ad8feebae240bc90 240 SUPERFAMILY SSF46894 118 218 5.39E-25 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 BWK49_RS03160 6b3849d78c90c349630bdb228030b2b5 470 PRINTS PR01874 DNA repair protein radA signature 318 341 5.1E-79 T 06-07-2017 BWK49_RS03160 6b3849d78c90c349630bdb228030b2b5 470 PRINTS PR01874 DNA repair protein radA signature 78 106 5.1E-79 T 06-07-2017 BWK49_RS03160 6b3849d78c90c349630bdb228030b2b5 470 PRINTS PR01874 DNA repair protein radA signature 10 34 5.1E-79 T 06-07-2017 BWK49_RS03160 6b3849d78c90c349630bdb228030b2b5 470 PRINTS PR01874 DNA repair protein radA signature 244 270 5.1E-79 T 06-07-2017 BWK49_RS03160 6b3849d78c90c349630bdb228030b2b5 470 PRINTS PR01874 DNA repair protein radA signature 209 237 5.1E-79 T 06-07-2017 BWK49_RS03160 6b3849d78c90c349630bdb228030b2b5 470 PRINTS PR01874 DNA repair protein radA signature 170 194 5.1E-79 T 06-07-2017 BWK49_RS03160 6b3849d78c90c349630bdb228030b2b5 470 PRINTS PR01874 DNA repair protein radA signature 120 137 5.1E-79 T 06-07-2017 BWK49_RS03160 6b3849d78c90c349630bdb228030b2b5 470 Pfam PF13481 AAA domain 80 218 5.3E-16 T 06-07-2017 BWK49_RS03160 6b3849d78c90c349630bdb228030b2b5 470 SUPERFAMILY SSF54211 299 454 1.52E-31 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold BWK49_RS03160 6b3849d78c90c349630bdb228030b2b5 470 SUPERFAMILY SSF54211 251 265 1.52E-31 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold BWK49_RS03160 6b3849d78c90c349630bdb228030b2b5 470 Gene3D G3DSA:3.30.230.10 283 452 6.2E-28 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup BWK49_RS03160 6b3849d78c90c349630bdb228030b2b5 470 TIGRFAM TIGR00416 sms: DNA repair protein RadA 1 447 4.0E-148 T 06-07-2017 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 BWK49_RS03160 6b3849d78c90c349630bdb228030b2b5 470 SMART SM00382 86 240 9.3E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS03160 6b3849d78c90c349630bdb228030b2b5 470 Hamap MF_01498 DNA repair protein RadA [radA]. 21 453 41.849 T 06-07-2017 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 BWK49_RS03160 6b3849d78c90c349630bdb228030b2b5 470 Pfam PF13541 Subunit ChlI of Mg-chelatase 328 424 8.1E-8 T 06-07-2017 BWK49_RS03160 6b3849d78c90c349630bdb228030b2b5 470 SUPERFAMILY SSF52540 67 287 5.42E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS03160 6b3849d78c90c349630bdb228030b2b5 470 Gene3D G3DSA:3.40.50.300 56 271 9.4E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS13595 436ef537471c868c57c77be7c03f0ebb 264 SUPERFAMILY SSF53448 19 248 8.25E-40 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases BWK49_RS13595 436ef537471c868c57c77be7c03f0ebb 264 Gene3D G3DSA:3.90.550.10 18 228 1.0E-19 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases BWK49_RS13595 436ef537471c868c57c77be7c03f0ebb 264 Pfam PF00535 Glycosyl transferase family 2 21 186 3.9E-28 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 BWK49_RS06700 c6e16a9b35c941747430ae7012e2afd4 299 SUPERFAMILY SSF51556 19 291 5.77E-49 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS06700 c6e16a9b35c941747430ae7012e2afd4 299 Pfam PF04909 Amidohydrolase 20 291 1.1E-26 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 BWK49_RS06700 c6e16a9b35c941747430ae7012e2afd4 299 Gene3D G3DSA:3.20.20.140 17 292 2.3E-57 T 06-07-2017 BWK49_RS11855 28a914586abb8df92f796c540e4279a5 371 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 61 75 - T 06-07-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 BWK49_RS11855 28a914586abb8df92f796c540e4279a5 371 SUPERFAMILY SSF50129 1 192 2.13E-59 T 06-07-2017 IPR011032 GroES-like BWK49_RS11855 28a914586abb8df92f796c540e4279a5 371 Gene3D G3DSA:3.40.50.720 191 312 9.9E-27 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS11855 28a914586abb8df92f796c540e4279a5 371 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 125 1.3E-26 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 BWK49_RS11855 28a914586abb8df92f796c540e4279a5 371 Gene3D G3DSA:3.90.180.10 1 190 2.3E-57 T 06-07-2017 IPR011032 GroES-like BWK49_RS11855 28a914586abb8df92f796c540e4279a5 371 TIGRFAM TIGR03989 Rxyl_3153: NDMA-dependent alcohol dehydrogenase, Rxyl_3153 family 2 369 5.1E-165 T 06-07-2017 IPR023921 Alcohol dehydrogenase, zinc-type, actinomycetes KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396 BWK49_RS11855 28a914586abb8df92f796c540e4279a5 371 Pfam PF00107 Zinc-binding dehydrogenase 196 326 2.6E-19 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 BWK49_RS11855 28a914586abb8df92f796c540e4279a5 371 SUPERFAMILY SSF51735 158 334 9.1E-36 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS11855 28a914586abb8df92f796c540e4279a5 371 SUPERFAMILY SSF50129 320 368 3.25E-9 T 06-07-2017 IPR011032 GroES-like BWK49_RS11855 28a914586abb8df92f796c540e4279a5 371 SMART SM00829 10 367 2.5E-5 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 BWK49_RS17510 7b96e406c37c4a0ac9d8b42e365feaf0 608 Gene3D G3DSA:2.30.38.10 388 449 7.0E-19 T 06-07-2017 BWK49_RS17510 7b96e406c37c4a0ac9d8b42e365feaf0 608 SUPERFAMILY SSF56801 7 275 1.96E-115 T 06-07-2017 BWK49_RS17510 7b96e406c37c4a0ac9d8b42e365feaf0 608 SUPERFAMILY SSF56801 328 590 1.96E-115 T 06-07-2017 BWK49_RS17510 7b96e406c37c4a0ac9d8b42e365feaf0 608 Pfam PF00501 AMP-binding enzyme 14 457 2.6E-92 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS17510 7b96e406c37c4a0ac9d8b42e365feaf0 608 Gene3D G3DSA:3.40.50.980 9 176 3.2E-37 T 06-07-2017 BWK49_RS17510 7b96e406c37c4a0ac9d8b42e365feaf0 608 Gene3D G3DSA:3.40.50.980 177 270 8.1E-29 T 06-07-2017 BWK49_RS17510 7b96e406c37c4a0ac9d8b42e365feaf0 608 Gene3D G3DSA:3.40.50.980 325 387 8.1E-29 T 06-07-2017 BWK49_RS17510 7b96e406c37c4a0ac9d8b42e365feaf0 608 ProSitePatterns PS00455 Putative AMP-binding domain signature. 172 183 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS18605 5dde8a8dab477813e06bd6ace0eefb26 323 TIGRFAM TIGR01809 Shik-DH-AROM: shikimate-5-dehydrogenase 57 319 4.7E-96 T 06-07-2017 IPR010110 Shikimate dehydrogenase, AroM-type GO:0004764|GO:0005737|GO:0055114 KEGG: 00400+4.2.1.10+1.1.1.25+2.7.1.71+2.5.1.19+4.2.3.4|MetaCyc: PWY-6163|MetaCyc: PWY-6164|MetaCyc: PWY-6416|MetaCyc: PWY-6707 BWK49_RS18605 5dde8a8dab477813e06bd6ace0eefb26 323 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 63 145 1.9E-19 T 06-07-2017 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 BWK49_RS18605 5dde8a8dab477813e06bd6ace0eefb26 323 SUPERFAMILY SSF53223 57 157 2.01E-24 T 06-07-2017 BWK49_RS18605 5dde8a8dab477813e06bd6ace0eefb26 323 SUPERFAMILY SSF51735 169 320 1.76E-28 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS18605 5dde8a8dab477813e06bd6ace0eefb26 323 Gene3D G3DSA:3.40.50.720 162 320 4.0E-33 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS18605 5dde8a8dab477813e06bd6ace0eefb26 323 Gene3D G3DSA:3.40.192.10 59 161 1.1E-31 T 06-07-2017 BWK49_RS10675 0006a53135d30e110c3bc656a7b1f68e 396 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 308 390 1.6E-12 T 06-07-2017 IPR022171 PPE family, C-terminal BWK49_RS10675 0006a53135d30e110c3bc656a7b1f68e 396 SUPERFAMILY SSF140459 2 173 9.42E-66 T 06-07-2017 BWK49_RS10675 0006a53135d30e110c3bc656a7b1f68e 396 Pfam PF00823 PPE family 5 162 2.5E-63 T 06-07-2017 IPR000030 PPE family BWK49_RS14610 676d85f2e50e992ad2ea84ba1309895f 209 Gene3D G3DSA:3.40.109.10 5 206 1.7E-33 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 BWK49_RS14610 676d85f2e50e992ad2ea84ba1309895f 209 Pfam PF00881 Nitroreductase family 13 174 1.2E-21 T 06-07-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 BWK49_RS14610 676d85f2e50e992ad2ea84ba1309895f 209 SUPERFAMILY SSF55469 6 68 3.8E-33 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 BWK49_RS14610 676d85f2e50e992ad2ea84ba1309895f 209 SUPERFAMILY SSF55469 97 207 3.8E-33 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 BWK49_RS09635 5f5945997b4558db2bb863458decf338 458 PRINTS PR00359 B-class P450 signature 310 337 7.3E-29 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS09635 5f5945997b4558db2bb863458decf338 458 PRINTS PR00359 B-class P450 signature 154 170 7.3E-29 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS09635 5f5945997b4558db2bb863458decf338 458 PRINTS PR00359 B-class P450 signature 359 368 7.3E-29 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS09635 5f5945997b4558db2bb863458decf338 458 PRINTS PR00359 B-class P450 signature 368 379 7.3E-29 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS09635 5f5945997b4558db2bb863458decf338 458 PRINTS PR00359 B-class P450 signature 293 304 7.3E-29 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS09635 5f5945997b4558db2bb863458decf338 458 PRINTS PR00359 B-class P450 signature 338 353 7.3E-29 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS09635 5f5945997b4558db2bb863458decf338 458 PRINTS PR00359 B-class P450 signature 171 186 7.3E-29 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS09635 5f5945997b4558db2bb863458decf338 458 PRINTS PR00359 B-class P450 signature 108 119 7.3E-29 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS09635 5f5945997b4558db2bb863458decf338 458 Gene3D G3DSA:1.10.630.10 22 421 1.7E-92 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS09635 5f5945997b4558db2bb863458decf338 458 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 361 370 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 BWK49_RS09635 5f5945997b4558db2bb863458decf338 458 SUPERFAMILY SSF48264 26 420 3.67E-73 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS09635 5f5945997b4558db2bb863458decf338 458 Pfam PF00067 Cytochrome P450 237 388 1.1E-16 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS13410 bcf2406bd32ede1bb7f9f36e5eea7b4e 64 Hamap MF_02106 Prokaryotic ubiquitin-like protein Pup [pup]. 1 64 16.811 T 06-07-2017 IPR008515 Ubiquitin-like, Pup BWK49_RS13410 bcf2406bd32ede1bb7f9f36e5eea7b4e 64 Pfam PF05639 Pup-like protein 3 64 3.4E-22 T 06-07-2017 IPR008515 Ubiquitin-like, Pup BWK49_RS13410 bcf2406bd32ede1bb7f9f36e5eea7b4e 64 TIGRFAM TIGR03687 pupylate_cterm: ubiquitin-like protein Pup 33 64 2.8E-21 T 06-07-2017 IPR008515 Ubiquitin-like, Pup BWK49_RS27405 5a5dcab8395aba359a2b283539edf02b 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 3.9E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27405 5a5dcab8395aba359a2b283539edf02b 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 3.9E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27405 5a5dcab8395aba359a2b283539edf02b 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 3.9E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27405 5a5dcab8395aba359a2b283539edf02b 247 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 237 3.2E-65 T 06-07-2017 BWK49_RS27405 5a5dcab8395aba359a2b283539edf02b 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 2.0E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27405 5a5dcab8395aba359a2b283539edf02b 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 2.0E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27405 5a5dcab8395aba359a2b283539edf02b 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 2.0E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27405 5a5dcab8395aba359a2b283539edf02b 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 201 221 2.0E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27405 5a5dcab8395aba359a2b283539edf02b 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 2.0E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27405 5a5dcab8395aba359a2b283539edf02b 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 2.0E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27405 5a5dcab8395aba359a2b283539edf02b 247 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS27405 5a5dcab8395aba359a2b283539edf02b 247 Gene3D G3DSA:3.40.50.720 2 239 6.4E-85 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS27405 5a5dcab8395aba359a2b283539edf02b 247 SUPERFAMILY SSF51735 5 238 4.35E-80 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS03320 188a84281bf43181d7d3c1ecab9f5f10 382 SUPERFAMILY SSF47203 231 376 1.01E-20 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS03320 188a84281bf43181d7d3c1ecab9f5f10 382 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 231 374 5.1E-28 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS03320 188a84281bf43181d7d3c1ecab9f5f10 382 Gene3D G3DSA:1.20.140.10 221 379 2.7E-26 T 06-07-2017 BWK49_RS03320 188a84281bf43181d7d3c1ecab9f5f10 382 SUPERFAMILY SSF56645 3 242 3.4E-68 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS03320 188a84281bf43181d7d3c1ecab9f5f10 382 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 125 218 8.7E-25 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 BWK49_RS03320 188a84281bf43181d7d3c1ecab9f5f10 382 Gene3D G3DSA:1.10.540.10 3 119 5.7E-23 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS03320 188a84281bf43181d7d3c1ecab9f5f10 382 Gene3D G3DSA:2.40.110.10 124 220 3.7E-36 T 06-07-2017 BWK49_RS03320 188a84281bf43181d7d3c1ecab9f5f10 382 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 3 119 1.7E-20 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS16965 997756b75857f1314e8a26c8309dcf02 294 Hamap MF_00082_B Acetylglutamate kinase [argB]. 27 293 33.028 T 06-07-2017 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 BWK49_RS16965 997756b75857f1314e8a26c8309dcf02 294 SUPERFAMILY SSF53633 12 293 8.12E-83 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase BWK49_RS16965 997756b75857f1314e8a26c8309dcf02 294 Gene3D G3DSA:3.40.1160.10 27 292 4.6E-96 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase BWK49_RS16965 997756b75857f1314e8a26c8309dcf02 294 PRINTS PR00474 Glutamate 5-kinase family signature 243 263 1.8E-9 T 06-07-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 BWK49_RS16965 997756b75857f1314e8a26c8309dcf02 294 PRINTS PR00474 Glutamate 5-kinase family signature 60 74 1.8E-9 T 06-07-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 BWK49_RS16965 997756b75857f1314e8a26c8309dcf02 294 PRINTS PR00474 Glutamate 5-kinase family signature 192 219 1.8E-9 T 06-07-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 BWK49_RS16965 997756b75857f1314e8a26c8309dcf02 294 TIGRFAM TIGR00761 argB: acetylglutamate kinase 31 268 4.0E-81 T 06-07-2017 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 BWK49_RS16965 997756b75857f1314e8a26c8309dcf02 294 PIRSF PIRSF000728 14 292 2.3E-98 T 06-07-2017 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 BWK49_RS16965 997756b75857f1314e8a26c8309dcf02 294 Pfam PF00696 Amino acid kinase family 29 270 2.0E-45 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase BWK49_RS19625 6183779ca645556f2365cbba3025a3f8 120 SMART SM00530 12 67 1.1E-10 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 BWK49_RS19625 6183779ca645556f2365cbba3025a3f8 120 Pfam PF13560 Helix-turn-helix domain 9 66 6.2E-14 T 06-07-2017 BWK49_RS19625 6183779ca645556f2365cbba3025a3f8 120 Gene3D G3DSA:1.10.260.40 9 87 3.2E-18 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 BWK49_RS19625 6183779ca645556f2365cbba3025a3f8 120 SUPERFAMILY SSF47413 3 73 2.08E-15 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 BWK49_RS20085 7951ffecc31991ddda1f83792cfc2117 403 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 16 386 44.481 T 06-07-2017 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 BWK49_RS20085 7951ffecc31991ddda1f83792cfc2117 403 SUPERFAMILY SSF51735 15 152 1.06E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS20085 7951ffecc31991ddda1f83792cfc2117 403 Gene3D G3DSA:1.10.1740.10 305 388 4.9E-31 T 06-07-2017 BWK49_RS20085 7951ffecc31991ddda1f83792cfc2117 403 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 15 388 2.8E-115 T 06-07-2017 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 BWK49_RS20085 7951ffecc31991ddda1f83792cfc2117 403 PIRSF PIRSF006205 13 392 5.9E-139 T 06-07-2017 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 BWK49_RS20085 7951ffecc31991ddda1f83792cfc2117 403 Gene3D G3DSA:3.40.50.720 15 152 1.5E-48 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS20085 7951ffecc31991ddda1f83792cfc2117 403 SUPERFAMILY SSF55347 130 266 6.87E-53 T 06-07-2017 BWK49_RS20085 7951ffecc31991ddda1f83792cfc2117 403 SUPERFAMILY SSF69055 295 388 1.44E-26 T 06-07-2017 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 BWK49_RS20085 7951ffecc31991ddda1f83792cfc2117 403 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 148 231 1.5E-33 T 06-07-2017 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 BWK49_RS20085 7951ffecc31991ddda1f83792cfc2117 403 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 16 136 1.7E-36 T 06-07-2017 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 BWK49_RS20085 7951ffecc31991ddda1f83792cfc2117 403 Pfam PF13288 DXP reductoisomerase C-terminal domain 264 381 1.3E-35 T 06-07-2017 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 BWK49_RS17025 fa8d99682751d5015bfe606d410015d5 1186 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 327 625 4.3E-101 T 06-07-2017 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal BWK49_RS17025 fa8d99682751d5015bfe606d410015d5 1186 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 702 1185 8.8E-137 T 06-07-2017 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 BWK49_RS17025 fa8d99682751d5015bfe606d410015d5 1186 PRINTS PR00982 Lysyl-tRNA synthetase signature 920 933 5.5E-32 T 06-07-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 BWK49_RS17025 fa8d99682751d5015bfe606d410015d5 1186 PRINTS PR00982 Lysyl-tRNA synthetase signature 1069 1085 5.5E-32 T 06-07-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 BWK49_RS17025 fa8d99682751d5015bfe606d410015d5 1186 PRINTS PR00982 Lysyl-tRNA synthetase signature 891 907 5.5E-32 T 06-07-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 BWK49_RS17025 fa8d99682751d5015bfe606d410015d5 1186 PRINTS PR00982 Lysyl-tRNA synthetase signature 938 955 5.5E-32 T 06-07-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 BWK49_RS17025 fa8d99682751d5015bfe606d410015d5 1186 PRINTS PR00982 Lysyl-tRNA synthetase signature 875 885 5.5E-32 T 06-07-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 BWK49_RS17025 fa8d99682751d5015bfe606d410015d5 1186 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 706 1186 34.778 T 06-07-2017 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 BWK49_RS17025 fa8d99682751d5015bfe606d410015d5 1186 Gene3D G3DSA:3.30.930.10 833 1181 1.2E-96 T 06-07-2017 BWK49_RS17025 fa8d99682751d5015bfe606d410015d5 1186 Gene3D G3DSA:2.40.50.140 701 830 2.0E-29 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS17025 fa8d99682751d5015bfe606d410015d5 1186 SUPERFAMILY SSF55681 838 1183 1.08E-95 T 06-07-2017 BWK49_RS17025 fa8d99682751d5015bfe606d410015d5 1186 Pfam PF01336 OB-fold nucleic acid binding domain 745 821 2.0E-10 T 06-07-2017 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 BWK49_RS17025 fa8d99682751d5015bfe606d410015d5 1186 SUPERFAMILY SSF50249 699 830 5.78E-30 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS17025 fa8d99682751d5015bfe606d410015d5 1186 Pfam PF00152 tRNA synthetases class II (D, K and N) 840 1182 4.7E-67 T 06-07-2017 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 BWK49_RS17025 fa8d99682751d5015bfe606d410015d5 1186 Pfam PF16995 Transmembrane region of lysyl-tRNA synthetase 94 308 4.2E-80 T 06-07-2017 IPR031553 Lysyl-tRNA synthetase, N-terminal transmembrane region KEGG: 00970+6.1.1.6 BWK49_RS25540 c8950fded8fc9ec80568591e3e07c9b4 303 Pfam PF00378 Enoyl-CoA hydratase/isomerase 16 239 1.2E-26 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 BWK49_RS25540 c8950fded8fc9ec80568591e3e07c9b4 303 SUPERFAMILY SSF52096 4 282 9.31E-54 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS25540 c8950fded8fc9ec80568591e3e07c9b4 303 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 118 138 - T 06-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 BWK49_RS25540 c8950fded8fc9ec80568591e3e07c9b4 303 Gene3D G3DSA:3.90.226.10 3 276 2.1E-54 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS22765 e2c4e82f2f5399ca8a1a20541e73b640 104 TIGRFAM TIGR02949 anti_SigH_actin: anti-sigma factor, TIGR02949 family 19 100 6.2E-33 T 06-07-2017 IPR014295 Anti-sigma factor BWK49_RS22765 e2c4e82f2f5399ca8a1a20541e73b640 104 Pfam PF13490 Putative zinc-finger 26 59 1.0E-10 T 06-07-2017 IPR027383 Putative zinc-finger BWK49_RS22765 e2c4e82f2f5399ca8a1a20541e73b640 104 TIGRFAM TIGR03988 antisig_RsrA: mycothiol system anti-sigma-R factor 26 100 5.1E-29 T 06-07-2017 IPR024020 Anti sigma-R factor, mycothiol system,RsrA BWK49_RS05195 60ce5d43539d4eb922165eaaa69dd492 289 Pfam PF10118 Predicted metal-dependent hydrolase 16 264 4.6E-77 T 06-07-2017 IPR016516 Uncharacterised conserved protein UCP07580 BWK49_RS05195 60ce5d43539d4eb922165eaaa69dd492 289 SUPERFAMILY SSF47240 229 260 3.65E-5 T 06-07-2017 IPR009078 Ferritin-like superfamily BWK49_RS05195 60ce5d43539d4eb922165eaaa69dd492 289 SUPERFAMILY SSF47240 69 198 3.65E-5 T 06-07-2017 IPR009078 Ferritin-like superfamily BWK49_RS05195 60ce5d43539d4eb922165eaaa69dd492 289 PIRSF PIRSF007580 1 283 1.4E-85 T 06-07-2017 IPR016516 Uncharacterised conserved protein UCP07580 BWK49_RS11495 6d90cc6d461d09c970840bd7f3c1d2e5 133 Pfam PF01022 Bacterial regulatory protein, arsR family 56 99 8.1E-15 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 BWK49_RS11495 6d90cc6d461d09c970840bd7f3c1d2e5 133 SMART SM00418 48 126 6.4E-28 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 BWK49_RS11495 6d90cc6d461d09c970840bd7f3c1d2e5 133 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 50 65 8.8E-14 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 BWK49_RS11495 6d90cc6d461d09c970840bd7f3c1d2e5 133 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 82 97 8.8E-14 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 BWK49_RS11495 6d90cc6d461d09c970840bd7f3c1d2e5 133 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 69 80 8.8E-14 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 BWK49_RS11495 6d90cc6d461d09c970840bd7f3c1d2e5 133 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 97 112 8.8E-14 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 BWK49_RS11495 6d90cc6d461d09c970840bd7f3c1d2e5 133 SUPERFAMILY SSF46785 36 121 1.39E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS11495 6d90cc6d461d09c970840bd7f3c1d2e5 133 Gene3D G3DSA:1.10.10.10 37 131 1.2E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS03500 eaa976ecac53aebcd52eb8daf08c2900 135 SUPERFAMILY SSF54427 8 127 1.6E-20 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS03500 eaa976ecac53aebcd52eb8daf08c2900 135 Gene3D G3DSA:3.10.450.50 10 128 8.5E-25 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS03500 eaa976ecac53aebcd52eb8daf08c2900 135 Pfam PF12680 SnoaL-like domain 12 117 5.2E-12 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain BWK49_RS03560 7539b83e25e82e46a789549fac26187d 237 Gene3D G3DSA:3.40.710.10 67 226 3.0E-5 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like BWK49_RS03560 7539b83e25e82e46a789549fac26187d 237 SUPERFAMILY SSF56601 10 114 3.15E-8 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like BWK49_RS07380 255df9c3423c2460c9428607e58f0d83 120 SMART SM00091 7 74 9.1E-4 T 06-07-2017 IPR000014 PAS domain BWK49_RS07380 255df9c3423c2460c9428607e58f0d83 120 SUPERFAMILY SSF55785 12 114 3.74E-15 T 06-07-2017 IPR000014 PAS domain BWK49_RS07380 255df9c3423c2460c9428607e58f0d83 120 Pfam PF13426 PAS domain 18 113 5.0E-10 T 06-07-2017 IPR000014 PAS domain BWK49_RS07380 255df9c3423c2460c9428607e58f0d83 120 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 13 115 4.6E-11 T 06-07-2017 IPR000014 PAS domain BWK49_RS07380 255df9c3423c2460c9428607e58f0d83 120 Gene3D G3DSA:3.30.450.20 12 113 3.5E-13 T 06-07-2017 BWK49_RS10290 f1f09f6fbab2f259e4fccee2ef9ea0ce 500 Gene3D G3DSA:3.40.50.720 316 344 4.8E-4 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS10290 f1f09f6fbab2f259e4fccee2ef9ea0ce 500 Gene3D G3DSA:3.40.50.720 181 215 4.8E-4 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS10290 f1f09f6fbab2f259e4fccee2ef9ea0ce 500 SUPERFAMILY SSF51905 268 487 1.68E-22 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS10290 f1f09f6fbab2f259e4fccee2ef9ea0ce 500 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 11 33 6.7E-6 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 BWK49_RS10290 f1f09f6fbab2f259e4fccee2ef9ea0ce 500 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 173 197 6.7E-6 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 BWK49_RS10290 f1f09f6fbab2f259e4fccee2ef9ea0ce 500 SUPERFAMILY SSF51905 13 226 9.19E-55 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS10290 f1f09f6fbab2f259e4fccee2ef9ea0ce 500 Gene3D G3DSA:3.50.50.60 382 487 2.2E-76 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS10290 f1f09f6fbab2f259e4fccee2ef9ea0ce 500 Gene3D G3DSA:3.50.50.60 13 180 2.2E-76 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS10290 f1f09f6fbab2f259e4fccee2ef9ea0ce 500 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 13 210 5.0E-17 T 06-07-2017 BWK49_RS07915 ba6e88988f61afd3c8b747aa4ab03129 132 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 117 1.6E-10 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain BWK49_RS07915 ba6e88988f61afd3c8b747aa4ab03129 132 SUPERFAMILY SSF54593 1 121 1.03E-20 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS07915 ba6e88988f61afd3c8b747aa4ab03129 132 Gene3D G3DSA:3.10.180.10 1 121 7.6E-31 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS10350 b7030d49325e15a1ad59f63a1cc6c986 846 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 802 841 1.0E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 BWK49_RS10350 b7030d49325e15a1ad59f63a1cc6c986 846 Gene3D G3DSA:1.10.10.10 801 840 1.1E-6 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS10350 b7030d49325e15a1ad59f63a1cc6c986 846 Pfam PF06527 TniQ 10 148 4.8E-21 T 06-07-2017 IPR009492 TniQ BWK49_RS10350 b7030d49325e15a1ad59f63a1cc6c986 846 SUPERFAMILY SSF46785 799 842 4.99E-6 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS17250 7b4ff8f46a2c9190c29aa7d45fc1d906 472 SUPERFAMILY SSF52935 322 468 2.22E-33 T 06-07-2017 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 BWK49_RS17250 7b4ff8f46a2c9190c29aa7d45fc1d906 472 Pfam PF00224 Pyruvate kinase, barrel domain 3 334 3.9E-118 T 06-07-2017 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 BWK49_RS17250 7b4ff8f46a2c9190c29aa7d45fc1d906 472 Pfam PF02887 Pyruvate kinase, alpha/beta domain 354 465 1.2E-22 T 06-07-2017 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 BWK49_RS17250 7b4ff8f46a2c9190c29aa7d45fc1d906 472 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 3 467 4.9E-170 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 BWK49_RS17250 7b4ff8f46a2c9190c29aa7d45fc1d906 472 SUPERFAMILY SSF50800 71 165 2.79E-24 T 06-07-2017 IPR011037 Pyruvate kinase-like, insert domain BWK49_RS17250 7b4ff8f46a2c9190c29aa7d45fc1d906 472 SUPERFAMILY SSF51621 166 335 4.19E-96 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 BWK49_RS17250 7b4ff8f46a2c9190c29aa7d45fc1d906 472 SUPERFAMILY SSF51621 2 76 4.19E-96 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 BWK49_RS17250 7b4ff8f46a2c9190c29aa7d45fc1d906 472 Gene3D G3DSA:2.40.33.10 74 167 3.2E-27 T 06-07-2017 IPR015806 Pyruvate kinase, beta-barrel insert domain GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 BWK49_RS17250 7b4ff8f46a2c9190c29aa7d45fc1d906 472 ProSitePatterns PS00110 Pyruvate kinase active site signature. 213 225 - T 06-07-2017 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 BWK49_RS17250 7b4ff8f46a2c9190c29aa7d45fc1d906 472 PRINTS PR01050 Pyruvate kinase family signature 185 199 3.3E-66 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 BWK49_RS17250 7b4ff8f46a2c9190c29aa7d45fc1d906 472 PRINTS PR01050 Pyruvate kinase family signature 267 291 3.3E-66 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 BWK49_RS17250 7b4ff8f46a2c9190c29aa7d45fc1d906 472 PRINTS PR01050 Pyruvate kinase family signature 311 327 3.3E-66 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 BWK49_RS17250 7b4ff8f46a2c9190c29aa7d45fc1d906 472 PRINTS PR01050 Pyruvate kinase family signature 215 241 3.3E-66 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 BWK49_RS17250 7b4ff8f46a2c9190c29aa7d45fc1d906 472 PRINTS PR01050 Pyruvate kinase family signature 60 76 3.3E-66 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 BWK49_RS17250 7b4ff8f46a2c9190c29aa7d45fc1d906 472 PRINTS PR01050 Pyruvate kinase family signature 242 266 3.3E-66 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 BWK49_RS17250 7b4ff8f46a2c9190c29aa7d45fc1d906 472 PRINTS PR01050 Pyruvate kinase family signature 292 310 3.3E-66 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 BWK49_RS17250 7b4ff8f46a2c9190c29aa7d45fc1d906 472 Gene3D G3DSA:3.40.1380.20 324 465 1.5E-34 T 06-07-2017 IPR015794 Pyruvate kinase, alpha/beta GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 BWK49_RS17250 7b4ff8f46a2c9190c29aa7d45fc1d906 472 Gene3D G3DSA:3.20.20.60 3 73 4.4E-100 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 BWK49_RS17250 7b4ff8f46a2c9190c29aa7d45fc1d906 472 Gene3D G3DSA:3.20.20.60 168 323 4.4E-100 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 BWK49_RS06550 91fa511bbaa928881ff73ee2cdac24ff 381 SUPERFAMILY SSF53901 253 358 4.1E-25 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS06550 91fa511bbaa928881ff73ee2cdac24ff 381 Gene3D G3DSA:3.40.47.10 19 106 4.4E-16 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS06550 91fa511bbaa928881ff73ee2cdac24ff 381 Gene3D G3DSA:3.40.47.10 185 215 4.4E-16 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS06550 91fa511bbaa928881ff73ee2cdac24ff 381 Gene3D G3DSA:3.40.47.10 133 174 6.9E-20 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS06550 91fa511bbaa928881ff73ee2cdac24ff 381 Gene3D G3DSA:3.40.47.10 240 379 6.9E-20 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS06550 91fa511bbaa928881ff73ee2cdac24ff 381 PIRSF PIRSF000429 1 381 2.6E-41 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 BWK49_RS06550 91fa511bbaa928881ff73ee2cdac24ff 381 Pfam PF00108 Thiolase, N-terminal domain 5 174 8.7E-12 T 06-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 BWK49_RS06550 91fa511bbaa928881ff73ee2cdac24ff 381 SUPERFAMILY SSF53901 4 220 8.77E-36 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS06550 91fa511bbaa928881ff73ee2cdac24ff 381 Pfam PF02803 Thiolase, C-terminal domain 254 379 1.8E-8 T 06-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 BWK49_RS09535 2a2cf1d2390de60850bb2c20845e8115 801 SUPERFAMILY SSF89796 12 379 2.62E-71 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS09535 2a2cf1d2390de60850bb2c20845e8115 801 Gene3D G3DSA:3.30.1540.10 620 702 3.7E-28 T 06-07-2017 BWK49_RS09535 2a2cf1d2390de60850bb2c20845e8115 801 Gene3D G3DSA:3.30.1540.10 243 309 4.6E-17 T 06-07-2017 BWK49_RS09535 2a2cf1d2390de60850bb2c20845e8115 801 SUPERFAMILY SSF89796 393 795 3.4E-110 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS09535 2a2cf1d2390de60850bb2c20845e8115 801 Pfam PF02515 CoA-transferase family III 14 373 3.8E-62 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 BWK49_RS09535 2a2cf1d2390de60850bb2c20845e8115 801 Pfam PF02515 CoA-transferase family III 395 770 1.7E-102 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 BWK49_RS09535 2a2cf1d2390de60850bb2c20845e8115 801 Gene3D G3DSA:3.40.50.10540 703 794 9.1E-91 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS09535 2a2cf1d2390de60850bb2c20845e8115 801 Gene3D G3DSA:3.40.50.10540 310 376 8.5E-61 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS09535 2a2cf1d2390de60850bb2c20845e8115 801 Gene3D G3DSA:3.40.50.10540 11 227 8.5E-61 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS09535 2a2cf1d2390de60850bb2c20845e8115 801 Gene3D G3DSA:3.40.50.10540 393 610 9.1E-91 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS07695 5d6a7347d61a27811c62f3ff019e5597 260 Gene3D G3DSA:1.10.12.10 203 260 1.2E-24 T 06-07-2017 IPR014748 Crontonase, C-terminal BWK49_RS07695 5d6a7347d61a27811c62f3ff019e5597 260 SUPERFAMILY SSF52096 4 259 7.32E-91 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS07695 5d6a7347d61a27811c62f3ff019e5597 260 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 101 121 - T 06-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 BWK49_RS07695 5d6a7347d61a27811c62f3ff019e5597 260 Pfam PF00378 Enoyl-CoA hydratase/isomerase 13 259 1.3E-82 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 BWK49_RS07695 5d6a7347d61a27811c62f3ff019e5597 260 Gene3D G3DSA:3.90.226.10 3 199 4.5E-76 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS22260 ecfd07370b35459d0fc79dd6a32fe7f5 255 Gene3D G3DSA:3.40.50.720 1 244 3.1E-42 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS22260 ecfd07370b35459d0fc79dd6a32fe7f5 255 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 131 159 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS22260 ecfd07370b35459d0fc79dd6a32fe7f5 255 SUPERFAMILY SSF51735 1 230 2.84E-44 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS22260 ecfd07370b35459d0fc79dd6a32fe7f5 255 Pfam PF00106 short chain dehydrogenase 1 176 1.7E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS22260 ecfd07370b35459d0fc79dd6a32fe7f5 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 8.0E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS22260 ecfd07370b35459d0fc79dd6a32fe7f5 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 70 81 8.0E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS22260 ecfd07370b35459d0fc79dd6a32fe7f5 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 116 132 8.0E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS22260 ecfd07370b35459d0fc79dd6a32fe7f5 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 163 8.0E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS14320 794b2405f02bd77bcef80568a2561748 348 SUPERFAMILY SSF53335 115 274 1.53E-25 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS14320 794b2405f02bd77bcef80568a2561748 348 Pfam PF13649 Methyltransferase domain 150 246 3.2E-13 T 06-07-2017 BWK49_RS14320 794b2405f02bd77bcef80568a2561748 348 Gene3D G3DSA:3.40.50.150 115 284 1.0E-21 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS06160 72d8c3b44f4ccb5ace6dd586f410615c 551 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 20 54 4.4E-9 T 06-07-2017 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal BWK49_RS06160 72d8c3b44f4ccb5ace6dd586f410615c 551 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 58 122 7.3E-13 T 06-07-2017 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal BWK49_RS06160 72d8c3b44f4ccb5ace6dd586f410615c 551 SUPERFAMILY SSF50249 6 128 2.06E-25 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS06160 72d8c3b44f4ccb5ace6dd586f410615c 551 SUPERFAMILY SSF53901 170 397 6.67E-15 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS06160 72d8c3b44f4ccb5ace6dd586f410615c 551 Gene3D G3DSA:3.40.47.10 315 351 4.0E-4 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS06160 72d8c3b44f4ccb5ace6dd586f410615c 551 Gene3D G3DSA:3.40.47.10 417 532 4.0E-4 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS06160 72d8c3b44f4ccb5ace6dd586f410615c 551 SUPERFAMILY SSF53901 434 538 2.2E-15 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS06160 72d8c3b44f4ccb5ace6dd586f410615c 551 Gene3D G3DSA:3.40.47.10 357 392 2.8E-6 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS06160 72d8c3b44f4ccb5ace6dd586f410615c 551 Gene3D G3DSA:3.40.47.10 185 278 2.8E-6 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS18195 c65f0801c4ceca2815eef88ebf4d4224 324 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 88 7.3E-12 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 BWK49_RS18195 c65f0801c4ceca2815eef88ebf4d4224 324 Pfam PF00107 Zinc-binding dehydrogenase 149 254 6.6E-26 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 BWK49_RS18195 c65f0801c4ceca2815eef88ebf4d4224 324 SUPERFAMILY SSF51735 110 273 4.09E-41 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS18195 c65f0801c4ceca2815eef88ebf4d4224 324 Gene3D G3DSA:3.90.180.10 1 145 9.7E-45 T 06-07-2017 IPR011032 GroES-like BWK49_RS18195 c65f0801c4ceca2815eef88ebf4d4224 324 SUPERFAMILY SSF50129 1 142 1.67E-38 T 06-07-2017 IPR011032 GroES-like BWK49_RS18195 c65f0801c4ceca2815eef88ebf4d4224 324 SMART SM00829 10 322 8.7E-21 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 BWK49_RS18195 c65f0801c4ceca2815eef88ebf4d4224 324 Gene3D G3DSA:3.40.50.720 146 252 2.9E-27 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS15020 ad2eab3c671e89c69116817c10280ff0 522 Pfam PF00501 AMP-binding enzyme 24 421 6.6E-48 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS15020 ad2eab3c671e89c69116817c10280ff0 522 ProSitePatterns PS00455 Putative AMP-binding domain signature. 162 173 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS15020 ad2eab3c671e89c69116817c10280ff0 522 Gene3D G3DSA:2.30.38.10 350 414 3.4E-11 T 06-07-2017 BWK49_RS15020 ad2eab3c671e89c69116817c10280ff0 522 Gene3D G3DSA:3.30.300.30 415 517 1.3E-17 T 06-07-2017 BWK49_RS15020 ad2eab3c671e89c69116817c10280ff0 522 SUPERFAMILY SSF56801 17 519 3.79E-79 T 06-07-2017 BWK49_RS15020 ad2eab3c671e89c69116817c10280ff0 522 Gene3D G3DSA:3.40.50.980 17 167 2.4E-9 T 06-07-2017 BWK49_RS15020 ad2eab3c671e89c69116817c10280ff0 522 Gene3D G3DSA:3.40.50.980 168 327 2.5E-24 T 06-07-2017 BWK49_RS09755 726dae050389517a6eb0cca12ef28f70 351 Gene3D G3DSA:3.40.50.920 222 344 2.6E-40 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 BWK49_RS09755 726dae050389517a6eb0cca12ef28f70 351 Gene3D G3DSA:3.40.50.970 27 219 2.4E-70 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS09755 726dae050389517a6eb0cca12ef28f70 351 SMART SM00861 29 204 3.9E-62 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain BWK49_RS09755 726dae050389517a6eb0cca12ef28f70 351 Pfam PF02779 Transketolase, pyrimidine binding domain 28 203 7.3E-40 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain BWK49_RS09755 726dae050389517a6eb0cca12ef28f70 351 Pfam PF02780 Transketolase, C-terminal domain 218 339 3.1E-36 T 06-07-2017 IPR033248 Transketolase, C-terminal domain BWK49_RS09755 726dae050389517a6eb0cca12ef28f70 351 SUPERFAMILY SSF52518 29 207 1.28E-62 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS09755 726dae050389517a6eb0cca12ef28f70 351 SUPERFAMILY SSF52922 216 348 2.49E-37 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 BWK49_RS03255 a4e73f794cf6e385851c661c500a63c6 297 SUPERFAMILY SSF51735 2 286 1.2E-39 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS03255 a4e73f794cf6e385851c661c500a63c6 297 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 215 8.3E-13 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 BWK49_RS03255 a4e73f794cf6e385851c661c500a63c6 297 Gene3D G3DSA:3.40.50.720 2 282 8.7E-31 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS23195 6396624a1f250b1d121ea42c21306aae 299 ProSitePatterns PS00380 Rhodanese signature 1. 47 58 - T 06-07-2017 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 BWK49_RS23195 6396624a1f250b1d121ea42c21306aae 299 SUPERFAMILY SSF52821 167 288 1.83E-32 T 06-07-2017 IPR001763 Rhodanese-like domain BWK49_RS23195 6396624a1f250b1d121ea42c21306aae 299 ProSitePatterns PS00683 Rhodanese C-terminal signature. 267 277 - T 06-07-2017 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 BWK49_RS23195 6396624a1f250b1d121ea42c21306aae 299 Gene3D G3DSA:3.40.250.10 14 149 6.3E-34 T 06-07-2017 IPR001763 Rhodanese-like domain BWK49_RS23195 6396624a1f250b1d121ea42c21306aae 299 SMART SM00450 21 135 9.5E-19 T 06-07-2017 IPR001763 Rhodanese-like domain BWK49_RS23195 6396624a1f250b1d121ea42c21306aae 299 SMART SM00450 158 283 1.9E-20 T 06-07-2017 IPR001763 Rhodanese-like domain BWK49_RS23195 6396624a1f250b1d121ea42c21306aae 299 SUPERFAMILY SSF52821 14 153 3.8E-35 T 06-07-2017 IPR001763 Rhodanese-like domain BWK49_RS23195 6396624a1f250b1d121ea42c21306aae 299 Gene3D G3DSA:3.40.250.10 173 287 3.9E-33 T 06-07-2017 IPR001763 Rhodanese-like domain BWK49_RS23195 6396624a1f250b1d121ea42c21306aae 299 Pfam PF00581 Rhodanese-like domain 22 131 1.1E-14 T 06-07-2017 IPR001763 Rhodanese-like domain BWK49_RS23195 6396624a1f250b1d121ea42c21306aae 299 Pfam PF00581 Rhodanese-like domain 168 279 3.4E-15 T 06-07-2017 IPR001763 Rhodanese-like domain BWK49_RS17940 1dc16a743d6769f0bba6f33d4b52ea84 609 SUPERFAMILY SSF47203 292 468 3.87E-31 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS17940 1dc16a743d6769f0bba6f33d4b52ea84 609 Gene3D G3DSA:1.10.540.10 36 148 1.7E-6 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS17940 1dc16a743d6769f0bba6f33d4b52ea84 609 Gene3D G3DSA:1.20.140.10 272 468 7.3E-43 T 06-07-2017 BWK49_RS17940 1dc16a743d6769f0bba6f33d4b52ea84 609 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 162 272 1.2E-16 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 BWK49_RS17940 1dc16a743d6769f0bba6f33d4b52ea84 609 SUPERFAMILY SSF56645 36 295 1.05E-42 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS17940 1dc16a743d6769f0bba6f33d4b52ea84 609 Gene3D G3DSA:2.40.110.10 161 271 4.1E-23 T 06-07-2017 BWK49_RS17940 1dc16a743d6769f0bba6f33d4b52ea84 609 Pfam PF12418 Acyl-CoA dehydrogenase N terminal 3 34 1.4E-11 T 06-07-2017 IPR020953 Acyl-CoA dehydrogenase, N-terminal, bacteria BWK49_RS17940 1dc16a743d6769f0bba6f33d4b52ea84 609 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 474 604 2.4E-31 T 06-07-2017 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain BWK49_RS17940 1dc16a743d6769f0bba6f33d4b52ea84 609 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 288 455 8.1E-18 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS06745 dba4c99181ebb1f12cb7593d2db02854 369 Pfam PF12706 Beta-lactamase superfamily domain 122 318 7.1E-53 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS06745 dba4c99181ebb1f12cb7593d2db02854 369 SUPERFAMILY SSF56281 89 335 7.47E-38 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS06745 dba4c99181ebb1f12cb7593d2db02854 369 PIRSF PIRSF038896 2 368 5.0E-108 T 06-07-2017 IPR024884 N-acyl-phosphatidylethanolamine-hydrolysing phospholipase D GO:0008270|GO:0070290 Reactome: R-HSA-2466712 BWK49_RS06745 dba4c99181ebb1f12cb7593d2db02854 369 Gene3D G3DSA:3.60.15.10 65 367 2.5E-109 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS20780 06644fdd6547c3047fb58643670ee1d0 63 SUPERFAMILY SSF143800 1 62 2.16E-23 T 06-07-2017 BWK49_RS20780 06644fdd6547c3047fb58643670ee1d0 63 Pfam PF00830 Ribosomal L28 family 4 59 8.1E-22 T 06-07-2017 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS20780 06644fdd6547c3047fb58643670ee1d0 63 Gene3D G3DSA:2.30.170.40 2 60 2.5E-22 T 06-07-2017 BWK49_RS20780 06644fdd6547c3047fb58643670ee1d0 63 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 57 1.4E-23 T 06-07-2017 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS20780 06644fdd6547c3047fb58643670ee1d0 63 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 63 18.002 T 06-07-2017 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS02620 938f301017faafb3d9623f3864be93ba 331 PIRSF PIRSF002849 2 331 8.0E-131 T 06-07-2017 IPR016366 ATPase chaperone, AAA-type, MoxR, predicted BWK49_RS02620 938f301017faafb3d9623f3864be93ba 331 SMART SM00382 52 193 2.7E-4 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS02620 938f301017faafb3d9623f3864be93ba 331 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 55 185 4.8E-63 T 06-07-2017 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 BWK49_RS02620 938f301017faafb3d9623f3864be93ba 331 SUPERFAMILY SSF52540 19 303 1.29E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS02620 938f301017faafb3d9623f3864be93ba 331 Gene3D G3DSA:1.10.8.300 221 327 1.2E-35 T 06-07-2017 BWK49_RS02620 938f301017faafb3d9623f3864be93ba 331 Gene3D G3DSA:3.40.50.300 37 201 4.3E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS07795 310a7d21e57831d79adb0adb7adbf93d 275 Gene3D G3DSA:1.10.620.20 2 269 9.1E-75 T 06-07-2017 IPR012348 Ribonucleotide reductase-related GO:0016491|GO:0055114 Reactome: R-HSA-499943 BWK49_RS07795 310a7d21e57831d79adb0adb7adbf93d 275 PIRSF PIRSF000346 1 271 1.2E-73 T 06-07-2017 IPR005067 Fatty acid desaturase, type 2 GO:0006631|GO:0045300|GO:0055114 BWK49_RS07795 310a7d21e57831d79adb0adb7adbf93d 275 SUPERFAMILY SSF47240 2 269 6.76E-65 T 06-07-2017 IPR009078 Ferritin-like superfamily BWK49_RS07795 310a7d21e57831d79adb0adb7adbf93d 275 Pfam PF03405 Fatty acid desaturase 12 265 4.0E-35 T 06-07-2017 IPR005067 Fatty acid desaturase, type 2 GO:0006631|GO:0045300|GO:0055114 BWK49_RS25915 529525dfe0ecb0d69c884fa1e94f63f2 387 SUPERFAMILY SSF53067 8 184 6.47E-59 T 06-07-2017 BWK49_RS25915 529525dfe0ecb0d69c884fa1e94f63f2 387 Hamap MF_00020 Acetate kinase [ackA]. 1 387 158.643 T 06-07-2017 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 BWK49_RS25915 529525dfe0ecb0d69c884fa1e94f63f2 387 PRINTS PR00471 Acetate kinase family signature 310 326 3.7E-42 T 06-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 BWK49_RS25915 529525dfe0ecb0d69c884fa1e94f63f2 387 PRINTS PR00471 Acetate kinase family signature 9 20 3.7E-42 T 06-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 BWK49_RS25915 529525dfe0ecb0d69c884fa1e94f63f2 387 PRINTS PR00471 Acetate kinase family signature 365 377 3.7E-42 T 06-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 BWK49_RS25915 529525dfe0ecb0d69c884fa1e94f63f2 387 PRINTS PR00471 Acetate kinase family signature 162 175 3.7E-42 T 06-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 BWK49_RS25915 529525dfe0ecb0d69c884fa1e94f63f2 387 PRINTS PR00471 Acetate kinase family signature 192 213 3.7E-42 T 06-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 BWK49_RS25915 529525dfe0ecb0d69c884fa1e94f63f2 387 PRINTS PR00471 Acetate kinase family signature 288 301 3.7E-42 T 06-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 BWK49_RS25915 529525dfe0ecb0d69c884fa1e94f63f2 387 TIGRFAM TIGR00016 ackA: acetate kinase 7 383 8.2E-124 T 06-07-2017 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 BWK49_RS25915 529525dfe0ecb0d69c884fa1e94f63f2 387 Pfam PF00871 Acetokinase family 9 378 1.1E-127 T 06-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 BWK49_RS25915 529525dfe0ecb0d69c884fa1e94f63f2 387 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 9 20 - T 06-07-2017 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 BWK49_RS25915 529525dfe0ecb0d69c884fa1e94f63f2 387 Gene3D G3DSA:3.30.420.40 194 383 1.8E-72 T 06-07-2017 BWK49_RS25915 529525dfe0ecb0d69c884fa1e94f63f2 387 PIRSF PIRSF000722 5 387 3.9E-127 T 06-07-2017 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 BWK49_RS25915 529525dfe0ecb0d69c884fa1e94f63f2 387 SUPERFAMILY SSF53067 146 385 1.65E-79 T 06-07-2017 BWK49_RS25915 529525dfe0ecb0d69c884fa1e94f63f2 387 Gene3D G3DSA:3.30.420.40 9 193 7.1E-11 T 06-07-2017 BWK49_RS02080 fdde4ba7ed2b4f60ef98cd090a71482e 119 Gene3D G3DSA:3.10.450.50 6 116 3.2E-15 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS02080 fdde4ba7ed2b4f60ef98cd090a71482e 119 Pfam PF12680 SnoaL-like domain 18 108 2.0E-13 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain BWK49_RS02080 fdde4ba7ed2b4f60ef98cd090a71482e 119 SUPERFAMILY SSF54427 8 115 5.59E-18 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS15170 c57d921533a292f8f73b0e189da7f7a9 105 Pfam PF05305 Protein of unknown function (DUF732) 5 100 6.4E-27 T 06-07-2017 IPR007969 Domain of unknown function DUF732 BWK49_RS02505 a3c70fb27d434b34d339d2fe403c3758 235 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 7 201 2.9E-36 T 06-07-2017 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 BWK49_RS02505 a3c70fb27d434b34d339d2fe403c3758 235 SUPERFAMILY SSF52317 18 213 2.06E-20 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like BWK49_RS02505 a3c70fb27d434b34d339d2fe403c3758 235 Gene3D G3DSA:3.40.50.880 7 212 4.0E-19 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like BWK49_RS13050 51dd318daa7d7e385516afa56bcc1d25 691 SUPERFAMILY SSF56519 143 324 4.05E-28 T 06-07-2017 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 BWK49_RS13050 51dd318daa7d7e385516afa56bcc1d25 691 Pfam PF03717 Penicillin-binding Protein dimerisation domain 143 306 4.8E-9 T 06-07-2017 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 BWK49_RS13050 51dd318daa7d7e385516afa56bcc1d25 691 Gene3D G3DSA:3.90.1310.10 232 331 2.0E-25 T 06-07-2017 BWK49_RS13050 51dd318daa7d7e385516afa56bcc1d25 691 Gene3D G3DSA:3.40.710.10 332 672 2.6E-86 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like BWK49_RS13050 51dd318daa7d7e385516afa56bcc1d25 691 Pfam PF00905 Penicillin binding protein transpeptidase domain 351 666 1.4E-84 T 06-07-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 BWK49_RS13050 51dd318daa7d7e385516afa56bcc1d25 691 SUPERFAMILY SSF56601 325 678 9.9E-94 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like BWK49_RS14850 01692302345be28cf0035bb0138961be 419 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 305 311 - T 06-07-2017 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 BWK49_RS14850 01692302345be28cf0035bb0138961be 419 Pfam PF01070 FMN-dependent dehydrogenase 50 408 1.2E-123 T 06-07-2017 IPR000262 FMN-dependent dehydrogenase GO:0016491 BWK49_RS14850 01692302345be28cf0035bb0138961be 419 SUPERFAMILY SSF51395 41 407 1.79E-93 T 06-07-2017 BWK49_RS14850 01692302345be28cf0035bb0138961be 419 PIRSF PIRSF000138 20 412 2.7E-124 T 06-07-2017 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 BWK49_RS14850 01692302345be28cf0035bb0138961be 419 Gene3D G3DSA:3.20.20.70 41 409 2.2E-126 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 BWK49_RS05755 4a471118a4ed5c375f8b96ea02552157 472 Pfam PF00155 Aminotransferase class I and II 124 401 1.1E-17 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 BWK49_RS05755 4a471118a4ed5c375f8b96ea02552157 472 Gene3D G3DSA:3.40.640.10 145 355 3.2E-44 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 BWK49_RS05755 4a471118a4ed5c375f8b96ea02552157 472 SMART SM00345 28 87 4.7E-13 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 BWK49_RS05755 4a471118a4ed5c375f8b96ea02552157 472 Gene3D G3DSA:1.10.10.10 26 89 6.8E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS05755 4a471118a4ed5c375f8b96ea02552157 472 SUPERFAMILY SSF46785 19 97 2.59E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS05755 4a471118a4ed5c375f8b96ea02552157 472 SUPERFAMILY SSF53383 104 462 2.33E-75 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase BWK49_RS05755 4a471118a4ed5c375f8b96ea02552157 472 Pfam PF00392 Bacterial regulatory proteins, gntR family 27 87 1.3E-13 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 BWK49_RS05755 4a471118a4ed5c375f8b96ea02552157 472 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 61 1.3E-5 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 BWK49_RS05755 4a471118a4ed5c375f8b96ea02552157 472 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 61 77 1.3E-5 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 BWK49_RS12195 9754a733282cd6dcdaa0d51caacfab2e 424 Gene3D G3DSA:3.40.50.1820 153 411 6.9E-65 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS12195 9754a733282cd6dcdaa0d51caacfab2e 424 Pfam PF07859 alpha/beta hydrolase fold 185 392 3.7E-20 T 06-07-2017 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 BWK49_RS12195 9754a733282cd6dcdaa0d51caacfab2e 424 SUPERFAMILY SSF53474 161 398 3.1E-51 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS27485 205a3c94ecdf69bbeebe225ea8ce82e1 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 24 37 1.2E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS27485 205a3c94ecdf69bbeebe225ea8ce82e1 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 68 1.2E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS27485 205a3c94ecdf69bbeebe225ea8ce82e1 210 SUPERFAMILY SSF46689 11 88 1.9E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS27485 205a3c94ecdf69bbeebe225ea8ce82e1 210 SUPERFAMILY SSF48498 90 200 1.27E-13 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS27485 205a3c94ecdf69bbeebe225ea8ce82e1 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 70 3.4E-16 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS27485 205a3c94ecdf69bbeebe225ea8ce82e1 210 Gene3D G3DSA:1.10.357.10 11 207 6.3E-35 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS20390 468545da227c986aa66681542b79ff0b 137 SUPERFAMILY SSF82784 4 132 6.15E-20 T 06-07-2017 IPR003718 OsmC/Ohr family BWK49_RS20390 468545da227c986aa66681542b79ff0b 137 Gene3D G3DSA:3.30.300.20 9 132 5.0E-10 T 06-07-2017 IPR015946 K homology domain-like, alpha/beta BWK49_RS20390 468545da227c986aa66681542b79ff0b 137 Pfam PF02566 OsmC-like protein 34 130 1.6E-10 T 06-07-2017 IPR003718 OsmC/Ohr family BWK49_RS15860 60689c52f94c17c29570f8d6ac5f9261 142 Pfam PF13577 SnoaL-like domain 2 126 6.5E-24 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain BWK49_RS15860 60689c52f94c17c29570f8d6ac5f9261 142 SUPERFAMILY SSF54427 1 127 4.67E-30 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS15860 60689c52f94c17c29570f8d6ac5f9261 142 Gene3D G3DSA:3.10.450.50 1 126 8.7E-30 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS23930 008e280ed0f69e95c2e409e509add43a 444 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 172 191 3.5E-12 T 06-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 BWK49_RS23930 008e280ed0f69e95c2e409e509add43a 444 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 232 247 3.5E-12 T 06-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 BWK49_RS23930 008e280ed0f69e95c2e409e509add43a 444 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 95 109 3.5E-12 T 06-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 BWK49_RS23930 008e280ed0f69e95c2e409e509add43a 444 Gene3D G3DSA:3.40.120.10 3 151 5.0E-42 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 BWK49_RS23930 008e280ed0f69e95c2e409e509add43a 444 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 5 441 1.7E-185 T 06-07-2017 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 BWK49_RS23930 008e280ed0f69e95c2e409e509add43a 444 SUPERFAMILY SSF53738 156 255 1.53E-26 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 BWK49_RS23930 008e280ed0f69e95c2e409e509add43a 444 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 96 105 - T 06-07-2017 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 BWK49_RS23930 008e280ed0f69e95c2e409e509add43a 444 SUPERFAMILY SSF53738 3 179 3.65E-45 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 BWK49_RS23930 008e280ed0f69e95c2e409e509add43a 444 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 372 440 1.3E-15 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 BWK49_RS23930 008e280ed0f69e95c2e409e509add43a 444 Gene3D G3DSA:3.40.120.10 175 248 6.8E-25 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 BWK49_RS23930 008e280ed0f69e95c2e409e509add43a 444 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 133 1.3E-40 T 06-07-2017 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 BWK49_RS23930 008e280ed0f69e95c2e409e509add43a 444 Gene3D G3DSA:3.30.310.50 368 441 1.6E-19 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 BWK49_RS23930 008e280ed0f69e95c2e409e509add43a 444 Gene3D G3DSA:3.40.120.10 249 366 6.8E-30 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 BWK49_RS23930 008e280ed0f69e95c2e409e509add43a 444 SUPERFAMILY SSF53738 256 363 5.1E-26 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 BWK49_RS23930 008e280ed0f69e95c2e409e509add43a 444 SUPERFAMILY SSF55957 357 443 3.01E-22 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 BWK49_RS23930 008e280ed0f69e95c2e409e509add43a 444 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 157 252 1.4E-18 T 06-07-2017 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 BWK49_RS23930 008e280ed0f69e95c2e409e509add43a 444 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 1 443 43.779 T 06-07-2017 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 BWK49_RS23930 008e280ed0f69e95c2e409e509add43a 444 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 256 365 4.3E-28 T 06-07-2017 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 BWK49_RS19915 0567da41a7fb7ba370445b5a0b2b9969 923 Pfam PF11987 Translation-initiation factor 2 712 814 1.4E-32 T 06-07-2017 IPR023115 Translation initiation factor IF- 2, domain 3 BWK49_RS19915 0567da41a7fb7ba370445b5a0b2b9969 923 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 421 582 5.8E-32 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 BWK49_RS19915 0567da41a7fb7ba370445b5a0b2b9969 923 Gene3D G3DSA:2.40.30.10 826 922 1.7E-32 T 06-07-2017 BWK49_RS19915 0567da41a7fb7ba370445b5a0b2b9969 923 ProSitePatterns PS01176 Initiation factor 2 signature. 876 898 - T 06-07-2017 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 BWK49_RS19915 0567da41a7fb7ba370445b5a0b2b9969 923 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 4 922 16.644 T 06-07-2017 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 BWK49_RS19915 0567da41a7fb7ba370445b5a0b2b9969 923 Gene3D G3DSA:3.40.50.10050 723 803 8.6E-21 T 06-07-2017 IPR023115 Translation initiation factor IF- 2, domain 3 BWK49_RS19915 0567da41a7fb7ba370445b5a0b2b9969 923 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 339 384 2.2E-6 T 06-07-2017 IPR006847 Translation initiation factor IF-2, N-terminal BWK49_RS19915 0567da41a7fb7ba370445b5a0b2b9969 923 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 4 52 2.0E-14 T 06-07-2017 IPR006847 Translation initiation factor IF-2, N-terminal BWK49_RS19915 0567da41a7fb7ba370445b5a0b2b9969 923 SUPERFAMILY SSF50447 825 922 6.45E-26 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain BWK49_RS19915 0567da41a7fb7ba370445b5a0b2b9969 923 Gene3D G3DSA:2.40.30.10 595 688 5.5E-21 T 06-07-2017 BWK49_RS19915 0567da41a7fb7ba370445b5a0b2b9969 923 PRINTS PR00315 GTP-binding elongation factor signature 423 436 9.6E-10 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 BWK49_RS19915 0567da41a7fb7ba370445b5a0b2b9969 923 PRINTS PR00315 GTP-binding elongation factor signature 527 536 9.6E-10 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 BWK49_RS19915 0567da41a7fb7ba370445b5a0b2b9969 923 PRINTS PR00315 GTP-binding elongation factor signature 491 502 9.6E-10 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 BWK49_RS19915 0567da41a7fb7ba370445b5a0b2b9969 923 PRINTS PR00315 GTP-binding elongation factor signature 475 485 9.6E-10 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 BWK49_RS19915 0567da41a7fb7ba370445b5a0b2b9969 923 Pfam PF00009 Elongation factor Tu GTP binding domain 424 584 1.1E-32 T 06-07-2017 BWK49_RS19915 0567da41a7fb7ba370445b5a0b2b9969 923 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 331 923 6.7E-225 T 06-07-2017 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 BWK49_RS19915 0567da41a7fb7ba370445b5a0b2b9969 923 Gene3D G3DSA:3.40.50.300 414 583 1.4E-45 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS19915 0567da41a7fb7ba370445b5a0b2b9969 923 SUPERFAMILY SSF52540 415 586 2.22E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS19915 0567da41a7fb7ba370445b5a0b2b9969 923 SUPERFAMILY SSF50447 597 680 2.08E-23 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain BWK49_RS19915 0567da41a7fb7ba370445b5a0b2b9969 923 SUPERFAMILY SSF52156 704 831 1.44E-35 T 06-07-2017 IPR023115 Translation initiation factor IF- 2, domain 3 BWK49_RS05940 41301698c22b14ee36f5b5ec89f2269c 542 SUPERFAMILY SSF49503 421 536 2.48E-33 T 06-07-2017 IPR008972 Cupredoxin BWK49_RS05940 41301698c22b14ee36f5b5ec89f2269c 542 ProSitePatterns PS00079 Multicopper oxidases signature 1. 518 538 - T 06-07-2017 IPR033138 Multicopper oxidases, conserved site BWK49_RS05940 41301698c22b14ee36f5b5ec89f2269c 542 ProSitePatterns PS00080 Multicopper oxidases signature 2. 523 534 - T 06-07-2017 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 BWK49_RS05940 41301698c22b14ee36f5b5ec89f2269c 542 Gene3D G3DSA:2.60.40.420 59 193 1.3E-30 T 06-07-2017 IPR008972 Cupredoxin BWK49_RS05940 41301698c22b14ee36f5b5ec89f2269c 542 Gene3D G3DSA:2.60.40.420 424 539 8.8E-39 T 06-07-2017 IPR008972 Cupredoxin BWK49_RS05940 41301698c22b14ee36f5b5ec89f2269c 542 SUPERFAMILY SSF49503 266 399 3.35E-33 T 06-07-2017 IPR008972 Cupredoxin BWK49_RS05940 41301698c22b14ee36f5b5ec89f2269c 542 SUPERFAMILY SSF49503 194 236 3.35E-33 T 06-07-2017 IPR008972 Cupredoxin BWK49_RS05940 41301698c22b14ee36f5b5ec89f2269c 542 SUPERFAMILY SSF49503 69 192 7.21E-32 T 06-07-2017 IPR008972 Cupredoxin BWK49_RS05940 41301698c22b14ee36f5b5ec89f2269c 542 Pfam PF07732 Multicopper oxidase 89 191 3.6E-27 T 06-07-2017 IPR011707 Multicopper oxidase, type 3 GO:0005507 BWK49_RS05940 41301698c22b14ee36f5b5ec89f2269c 542 Pfam PF00394 Multicopper oxidase 200 387 1.9E-24 T 06-07-2017 IPR001117 Multicopper oxidase, type 1 GO:0016491|GO:0055114 BWK49_RS05940 41301698c22b14ee36f5b5ec89f2269c 542 Gene3D G3DSA:2.60.40.420 194 232 6.4E-47 T 06-07-2017 IPR008972 Cupredoxin BWK49_RS05940 41301698c22b14ee36f5b5ec89f2269c 542 Gene3D G3DSA:2.60.40.420 264 404 6.4E-47 T 06-07-2017 IPR008972 Cupredoxin BWK49_RS05940 41301698c22b14ee36f5b5ec89f2269c 542 Pfam PF07731 Multicopper oxidase 432 537 2.9E-28 T 06-07-2017 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 BWK49_RS24275 60dcc6adbd8e5a6903981321ec0153f1 786 Gene3D G3DSA:3.30.1120.10 496 579 3.8E-17 T 06-07-2017 BWK49_RS24275 60dcc6adbd8e5a6903981321ec0153f1 786 SUPERFAMILY SSF53649 35 574 9.16E-127 T 06-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 BWK49_RS24275 60dcc6adbd8e5a6903981321ec0153f1 786 Pfam PF00884 Sulfatase 36 464 3.6E-94 T 06-07-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 BWK49_RS24275 60dcc6adbd8e5a6903981321ec0153f1 786 ProSitePatterns PS00523 Sulfatases signature 1. 80 92 - T 06-07-2017 IPR024607 Sulfatase, conserved site BWK49_RS24275 60dcc6adbd8e5a6903981321ec0153f1 786 Gene3D G3DSA:3.40.720.10 33 492 2.6E-110 T 06-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 BWK49_RS24275 60dcc6adbd8e5a6903981321ec0153f1 786 ProSitePatterns PS00149 Sulfatases signature 2. 132 142 - T 06-07-2017 IPR024607 Sulfatase, conserved site BWK49_RS21455 65f297e544bd72e790afcd6c53212d73 431 Gene3D G3DSA:1.20.140.10 234 398 3.0E-40 T 06-07-2017 BWK49_RS21455 65f297e544bd72e790afcd6c53212d73 431 Gene3D G3DSA:1.10.540.10 4 130 3.6E-20 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS21455 65f297e544bd72e790afcd6c53212d73 431 SUPERFAMILY SSF56645 3 256 2.23E-60 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS21455 65f297e544bd72e790afcd6c53212d73 431 Gene3D G3DSA:2.40.110.10 132 233 8.9E-33 T 06-07-2017 BWK49_RS21455 65f297e544bd72e790afcd6c53212d73 431 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 13 127 3.0E-11 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS21455 65f297e544bd72e790afcd6c53212d73 431 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 133 215 2.6E-20 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 BWK49_RS21455 65f297e544bd72e790afcd6c53212d73 431 SUPERFAMILY SSF47203 243 397 3.7E-37 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS21455 65f297e544bd72e790afcd6c53212d73 431 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 246 393 1.0E-26 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS08155 fdd2ce8c0c9f74cd79134022ae2d9b38 360 Gene3D G3DSA:3.40.50.10540 2 301 2.2E-98 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS08155 fdd2ce8c0c9f74cd79134022ae2d9b38 360 Pfam PF02515 CoA-transferase family III 5 350 3.3E-78 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 BWK49_RS08155 fdd2ce8c0c9f74cd79134022ae2d9b38 360 SUPERFAMILY SSF89796 3 356 2.22E-108 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS12180 9b79048527fe696b4578ea0bc111cec3 392 SUPERFAMILY SSF52540 1 165 9.67E-25 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS12180 9b79048527fe696b4578ea0bc111cec3 392 SUPERFAMILY SSF52540 224 351 9.67E-25 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS12180 9b79048527fe696b4578ea0bc111cec3 392 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 23 348 7.7E-27 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 BWK49_RS12180 9b79048527fe696b4578ea0bc111cec3 392 Gene3D G3DSA:3.40.50.300 1 177 7.4E-31 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS12180 9b79048527fe696b4578ea0bc111cec3 392 Gene3D G3DSA:3.40.50.300 220 351 7.4E-31 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS12180 9b79048527fe696b4578ea0bc111cec3 392 PIRSF PIRSF029347 1 392 1.0E-128 T 06-07-2017 IPR014555 RecF-like BWK49_RS00540 bf18f49613891aaa9d2a211a9451109b 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.7E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS00540 bf18f49613891aaa9d2a211a9451109b 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 227 1.7E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS00540 bf18f49613891aaa9d2a211a9451109b 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 1.7E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS00540 bf18f49613891aaa9d2a211a9451109b 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 1.7E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS00540 bf18f49613891aaa9d2a211a9451109b 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 1.7E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS00540 bf18f49613891aaa9d2a211a9451109b 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 1.7E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS00540 bf18f49613891aaa9d2a211a9451109b 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 2.5E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS00540 bf18f49613891aaa9d2a211a9451109b 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 2.5E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS00540 bf18f49613891aaa9d2a211a9451109b 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 2.5E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS00540 bf18f49613891aaa9d2a211a9451109b 246 SUPERFAMILY SSF51735 5 242 1.15E-71 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS00540 bf18f49613891aaa9d2a211a9451109b 246 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS00540 bf18f49613891aaa9d2a211a9451109b 246 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 242 3.5E-54 T 06-07-2017 BWK49_RS00540 bf18f49613891aaa9d2a211a9451109b 246 Gene3D G3DSA:3.40.50.720 3 242 1.2E-74 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS19475 aef1a5114917c3515cef95a9f52c55a3 471 Gene3D G3DSA:3.50.50.60 5 144 8.8E-34 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS19475 aef1a5114917c3515cef95a9f52c55a3 471 Gene3D G3DSA:3.50.50.60 145 337 2.1E-52 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS19475 aef1a5114917c3515cef95a9f52c55a3 471 PIRSF PIRSF000350 1 468 6.2E-70 T 06-07-2017 BWK49_RS19475 aef1a5114917c3515cef95a9f52c55a3 471 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 328 2.0E-55 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS19475 aef1a5114917c3515cef95a9f52c55a3 471 SUPERFAMILY SSF51905 4 337 1.69E-52 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS19475 aef1a5114917c3515cef95a9f52c55a3 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 308 315 8.7E-56 T 06-07-2017 BWK49_RS19475 aef1a5114917c3515cef95a9f52c55a3 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 408 423 8.7E-56 T 06-07-2017 BWK49_RS19475 aef1a5114917c3515cef95a9f52c55a3 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 144 153 8.7E-56 T 06-07-2017 BWK49_RS19475 aef1a5114917c3515cef95a9f52c55a3 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 343 364 8.7E-56 T 06-07-2017 BWK49_RS19475 aef1a5114917c3515cef95a9f52c55a3 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 180 205 8.7E-56 T 06-07-2017 BWK49_RS19475 aef1a5114917c3515cef95a9f52c55a3 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 8 30 8.7E-56 T 06-07-2017 BWK49_RS19475 aef1a5114917c3515cef95a9f52c55a3 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 265 279 8.7E-56 T 06-07-2017 BWK49_RS19475 aef1a5114917c3515cef95a9f52c55a3 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 430 450 8.7E-56 T 06-07-2017 BWK49_RS19475 aef1a5114917c3515cef95a9f52c55a3 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 41 56 8.7E-56 T 06-07-2017 BWK49_RS19475 aef1a5114917c3515cef95a9f52c55a3 471 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 348 455 9.7E-26 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 BWK49_RS19475 aef1a5114917c3515cef95a9f52c55a3 471 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 3.4E-32 T 06-07-2017 BWK49_RS19475 aef1a5114917c3515cef95a9f52c55a3 471 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 180 198 3.4E-32 T 06-07-2017 BWK49_RS19475 aef1a5114917c3515cef95a9f52c55a3 471 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 293 315 3.4E-32 T 06-07-2017 BWK49_RS19475 aef1a5114917c3515cef95a9f52c55a3 471 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 264 280 3.4E-32 T 06-07-2017 BWK49_RS19475 aef1a5114917c3515cef95a9f52c55a3 471 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 141 159 3.4E-32 T 06-07-2017 BWK49_RS19475 aef1a5114917c3515cef95a9f52c55a3 471 SUPERFAMILY SSF55424 347 465 1.51E-29 T 06-07-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 BWK49_RS19475 aef1a5114917c3515cef95a9f52c55a3 471 Gene3D G3DSA:3.30.390.30 348 459 6.7E-28 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 BWK49_RS16425 58e83c71dc2552c71359c44b51a5a263 252 Gene3D G3DSA:3.40.50.1820 18 243 7.1E-24 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS16425 58e83c71dc2552c71359c44b51a5a263 252 Pfam PF00975 Thioesterase domain 21 241 3.0E-35 T 06-07-2017 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 BWK49_RS16425 58e83c71dc2552c71359c44b51a5a263 252 SUPERFAMILY SSF53474 16 243 5.72E-37 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS11595 fff6c178d6c40c7c80f11ffe188260df 650 SUPERFAMILY SSF56645 15 260 5.1E-53 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS11595 fff6c178d6c40c7c80f11ffe188260df 650 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 134 247 5.1E-18 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 BWK49_RS11595 fff6c178d6c40c7c80f11ffe188260df 650 SUPERFAMILY SSF47203 495 632 7.85E-36 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS11595 fff6c178d6c40c7c80f11ffe188260df 650 Gene3D G3DSA:1.20.140.10 500 628 1.1E-38 T 06-07-2017 BWK49_RS11595 fff6c178d6c40c7c80f11ffe188260df 650 Gene3D G3DSA:1.20.140.10 288 449 1.8E-53 T 06-07-2017 BWK49_RS11595 fff6c178d6c40c7c80f11ffe188260df 650 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 281 441 1.6E-11 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS11595 fff6c178d6c40c7c80f11ffe188260df 650 Gene3D G3DSA:1.10.540.10 51 131 9.8E-9 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS11595 fff6c178d6c40c7c80f11ffe188260df 650 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 22 129 2.0E-7 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS11595 fff6c178d6c40c7c80f11ffe188260df 650 SUPERFAMILY SSF47203 277 461 1.77E-49 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS11595 fff6c178d6c40c7c80f11ffe188260df 650 PIRSF PIRSF000168 1 648 3.8E-187 T 06-07-2017 IPR012258 Acyl-CoA oxidase GO:0003997|GO:0005777|GO:0006631|GO:0050660|GO:0055114 KEGG: 00071+1.3.3.6|KEGG: 00592+1.3.3.6|MetaCyc: PWY-5136|MetaCyc: PWY-6837|MetaCyc: PWY-6920|MetaCyc: PWY-7007|MetaCyc: PWY-7288|MetaCyc: PWY-7291|MetaCyc: PWY-7337|MetaCyc: PWY-7338|MetaCyc: PWY-7340|MetaCyc: PWY-735|MetaCyc: PWY-7606|MetaCyc: PWY-7726 BWK49_RS11595 fff6c178d6c40c7c80f11ffe188260df 650 Gene3D G3DSA:2.40.110.10 133 267 2.2E-44 T 06-07-2017 BWK49_RS11595 fff6c178d6c40c7c80f11ffe188260df 650 Pfam PF01756 Acyl-CoA oxidase 501 631 1.0E-21 T 06-07-2017 IPR002655 Acyl-CoA oxidase, C-terminal GO:0003997|GO:0005777|GO:0006635|GO:0055114 KEGG: 00071+1.3.3.6|KEGG: 00592+1.3.3.6|MetaCyc: PWY-5136|MetaCyc: PWY-6837|MetaCyc: PWY-6920|MetaCyc: PWY-7007|MetaCyc: PWY-7288|MetaCyc: PWY-7291|MetaCyc: PWY-7337|MetaCyc: PWY-7338|MetaCyc: PWY-7340|MetaCyc: PWY-735|MetaCyc: PWY-7606|MetaCyc: PWY-7726 BWK49_RS25795 db87570b38d460969ae9ed5d3c079fa8 482 SUPERFAMILY SSF55486 30 245 5.2E-22 T 06-07-2017 BWK49_RS06515 3adfb5c1d5dcfb5f14ad64c85696c799 402 Gene3D G3DSA:3.50.50.60 266 341 6.2E-28 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS06515 3adfb5c1d5dcfb5f14ad64c85696c799 402 Gene3D G3DSA:3.50.50.60 2 170 6.2E-28 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS06515 3adfb5c1d5dcfb5f14ad64c85696c799 402 SUPERFAMILY SSF51905 265 370 2.48E-42 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS06515 3adfb5c1d5dcfb5f14ad64c85696c799 402 SUPERFAMILY SSF51905 2 165 2.48E-42 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS06515 3adfb5c1d5dcfb5f14ad64c85696c799 402 Pfam PF01494 FAD binding domain 2 314 5.6E-13 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 BWK49_RS06515 3adfb5c1d5dcfb5f14ad64c85696c799 402 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 1.3E-10 T 06-07-2017 BWK49_RS06515 3adfb5c1d5dcfb5f14ad64c85696c799 402 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 278 293 1.3E-10 T 06-07-2017 BWK49_RS06515 3adfb5c1d5dcfb5f14ad64c85696c799 402 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 293 309 1.3E-10 T 06-07-2017 BWK49_RS06515 3adfb5c1d5dcfb5f14ad64c85696c799 402 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 144 159 1.3E-10 T 06-07-2017 BWK49_RS03185 0304c36c75164fcede24be9570ff1909 469 Pfam PF09190 DALR domain 342 394 1.1E-5 T 06-07-2017 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 BWK49_RS03185 0304c36c75164fcede24be9570ff1909 469 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 7 464 34.315 T 06-07-2017 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 BWK49_RS03185 0304c36c75164fcede24be9570ff1909 469 SMART SM00840 342 403 5.6E-10 T 06-07-2017 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 BWK49_RS03185 0304c36c75164fcede24be9570ff1909 469 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 66 75 1.1E-26 T 06-07-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 BWK49_RS03185 0304c36c75164fcede24be9570ff1909 469 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 193 211 1.1E-26 T 06-07-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 BWK49_RS03185 0304c36c75164fcede24be9570ff1909 469 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 30 41 1.1E-26 T 06-07-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 BWK49_RS03185 0304c36c75164fcede24be9570ff1909 469 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 224 245 1.1E-26 T 06-07-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 BWK49_RS03185 0304c36c75164fcede24be9570ff1909 469 SUPERFAMILY SSF52374 8 314 5.36E-88 T 06-07-2017 BWK49_RS03185 0304c36c75164fcede24be9570ff1909 469 Gene3D G3DSA:1.20.120.640 308 394 7.1E-12 T 06-07-2017 BWK49_RS03185 0304c36c75164fcede24be9570ff1909 469 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 20 314 4.3E-124 T 06-07-2017 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 BWK49_RS03185 0304c36c75164fcede24be9570ff1909 469 SUPERFAMILY SSF47323 322 463 3.66E-29 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 BWK49_RS03185 0304c36c75164fcede24be9570ff1909 469 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 7 462 1.2E-128 T 06-07-2017 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 BWK49_RS03185 0304c36c75164fcede24be9570ff1909 469 Gene3D G3DSA:3.40.50.620 24 306 2.4E-95 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold BWK49_RS16605 5609680399fc015a71335a38bb2ecb83 247 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 109 123 - T 06-07-2017 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 BWK49_RS16605 5609680399fc015a71335a38bb2ecb83 247 SMART SM00363 7 67 2.5E-10 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 BWK49_RS16605 5609680399fc015a71335a38bb2ecb83 247 Pfam PF01479 S4 domain 8 50 9.1E-14 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 BWK49_RS16605 5609680399fc015a71335a38bb2ecb83 247 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 73 233 2.7E-46 T 06-07-2017 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 BWK49_RS16605 5609680399fc015a71335a38bb2ecb83 247 Pfam PF00849 RNA pseudouridylate synthase 69 204 1.3E-20 T 06-07-2017 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 BWK49_RS16605 5609680399fc015a71335a38bb2ecb83 247 Gene3D G3DSA:3.10.290.10 5 69 6.3E-24 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 BWK49_RS16605 5609680399fc015a71335a38bb2ecb83 247 SUPERFAMILY SSF55174 3 61 3.34E-14 T 06-07-2017 BWK49_RS16605 5609680399fc015a71335a38bb2ecb83 247 SUPERFAMILY SSF55120 57 245 1.76E-43 T 06-07-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 BWK49_RS23495 e6aa2c41270f3d4d9529f8bf94d0068c 339 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 8 334 8.5E-101 T 06-07-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 BWK49_RS23495 e6aa2c41270f3d4d9529f8bf94d0068c 339 Gene3D G3DSA:1.10.240.10 212 302 1.6E-16 T 06-07-2017 BWK49_RS23495 e6aa2c41270f3d4d9529f8bf94d0068c 339 SUPERFAMILY SSF52374 9 334 3.14E-92 T 06-07-2017 BWK49_RS23495 e6aa2c41270f3d4d9529f8bf94d0068c 339 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 16 26 - T 06-07-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 BWK49_RS23495 e6aa2c41270f3d4d9529f8bf94d0068c 339 Gene3D G3DSA:3.40.50.620 9 211 2.3E-79 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold BWK49_RS23495 e6aa2c41270f3d4d9529f8bf94d0068c 339 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 71 90 9.2E-28 T 06-07-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 BWK49_RS23495 e6aa2c41270f3d4d9529f8bf94d0068c 339 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 21 37 9.2E-28 T 06-07-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 BWK49_RS23495 e6aa2c41270f3d4d9529f8bf94d0068c 339 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 201 211 9.2E-28 T 06-07-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 BWK49_RS23495 e6aa2c41270f3d4d9529f8bf94d0068c 339 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 148 169 9.2E-28 T 06-07-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 BWK49_RS23495 e6aa2c41270f3d4d9529f8bf94d0068c 339 Pfam PF00579 tRNA synthetases class I (W and Y) 5 289 2.3E-83 T 06-07-2017 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 BWK49_RS23495 e6aa2c41270f3d4d9529f8bf94d0068c 339 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 7 335 40.915 T 06-07-2017 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 BWK49_RS26775 f3155341948e4138b2b08014a63889f7 384 SUPERFAMILY SSF52283 3 177 3.02E-66 T 06-07-2017 BWK49_RS26775 f3155341948e4138b2b08014a63889f7 384 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 156 335 5.9E-46 T 06-07-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 BWK49_RS26775 f3155341948e4138b2b08014a63889f7 384 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 195 222 - T 06-07-2017 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 BWK49_RS26775 f3155341948e4138b2b08014a63889f7 384 Gene3D G3DSA:3.40.50.720 3 184 1.1E-85 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS26775 f3155341948e4138b2b08014a63889f7 384 Hamap MF_03210 Formate dehydrogenase, mitochondrial. 2 383 55.208 T 06-07-2017 IPR033689 NAD-dependent formate dehydrogenase GO:0008863 KEGG: 00630+1.2.1.2|KEGG: 00680+1.2.1.2|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696 BWK49_RS26775 f3155341948e4138b2b08014a63889f7 384 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 62 361 5.2E-21 T 06-07-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 BWK49_RS26775 f3155341948e4138b2b08014a63889f7 384 SUPERFAMILY SSF51735 147 336 4.01E-50 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS26775 f3155341948e4138b2b08014a63889f7 384 Gene3D G3DSA:3.40.50.720 187 343 4.0E-28 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS18445 0babe735b83edc1fd2e9019866c123e2 108 Gene3D G3DSA:3.90.940.10 33 106 1.1E-32 T 06-07-2017 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 BWK49_RS18445 0babe735b83edc1fd2e9019866c123e2 108 Pfam PF01192 RNA polymerase Rpb6 40 101 1.1E-13 T 06-07-2017 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 BWK49_RS18445 0babe735b83edc1fd2e9019866c123e2 108 SMART SM01409 40 104 1.9E-12 T 06-07-2017 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 BWK49_RS18445 0babe735b83edc1fd2e9019866c123e2 108 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 33 105 14.335 T 06-07-2017 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 BWK49_RS18445 0babe735b83edc1fd2e9019866c123e2 108 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 33 103 2.9E-27 T 06-07-2017 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 BWK49_RS18445 0babe735b83edc1fd2e9019866c123e2 108 SUPERFAMILY SSF63562 33 104 5.23E-22 T 06-07-2017 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 BWK49_RS27975 e90299db115fe0f5537e3d1378b5f7eb 278 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 173 264 4.4E-14 T 06-07-2017 BWK49_RS27975 e90299db115fe0f5537e3d1378b5f7eb 278 Pfam PF00106 short chain dehydrogenase 4 133 2.0E-16 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27975 e90299db115fe0f5537e3d1378b5f7eb 278 SUPERFAMILY SSF51735 168 267 1.54E-41 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS27975 e90299db115fe0f5537e3d1378b5f7eb 278 SUPERFAMILY SSF51735 2 133 1.54E-41 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS27975 e90299db115fe0f5537e3d1378b5f7eb 278 Gene3D G3DSA:3.40.50.720 170 269 2.8E-45 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS27975 e90299db115fe0f5537e3d1378b5f7eb 278 Gene3D G3DSA:3.40.50.720 2 135 2.8E-45 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS27975 e90299db115fe0f5537e3d1378b5f7eb 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 114 130 2.5E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27975 e90299db115fe0f5537e3d1378b5f7eb 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 2.5E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27975 e90299db115fe0f5537e3d1378b5f7eb 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 2.5E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27975 e90299db115fe0f5537e3d1378b5f7eb 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 193 2.5E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27975 e90299db115fe0f5537e3d1378b5f7eb 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 228 248 2.5E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27975 e90299db115fe0f5537e3d1378b5f7eb 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 195 212 2.5E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS13100 f11a838cd317ddd0db91a01350ca8067 316 Gene3D G3DSA:1.10.8.50 132 182 0.001 T 06-07-2017 BWK49_RS13100 f11a838cd317ddd0db91a01350ca8067 316 Pfam PF08478 POTRA domain, FtsQ-type 127 194 3.9E-16 T 06-07-2017 IPR013685 Polypeptide-transport-associated, FtsQ-type BWK49_RS13100 f11a838cd317ddd0db91a01350ca8067 316 Pfam PF03799 Cell division protein FtsQ 207 300 9.0E-7 T 06-07-2017 IPR005548 Cell division protein FtsQ/DivIB BWK49_RS13100 f11a838cd317ddd0db91a01350ca8067 316 Hamap MF_00911 Cell division protein FtsQ [ftsQ]. 96 316 18.198 T 06-07-2017 IPR026579 Cell division protein FtsQ GO:0090529 BWK49_RS16660 f008a544d31f9774ce08d5fd8bc80197 308 Gene3D G3DSA:2.60.200.30 157 275 1.3E-37 T 06-07-2017 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 BWK49_RS16660 f008a544d31f9774ce08d5fd8bc80197 308 Hamap MF_00361 NAD kinase [nadK]. 6 300 30.094 T 06-07-2017 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 BWK49_RS16660 f008a544d31f9774ce08d5fd8bc80197 308 Gene3D G3DSA:3.40.50.10330 6 156 1.3E-33 T 06-07-2017 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 BWK49_RS16660 f008a544d31f9774ce08d5fd8bc80197 308 SUPERFAMILY SSF111331 7 306 3.53E-82 T 06-07-2017 IPR016064 NAD kinase/diacylglycerol kinase-like domain BWK49_RS16660 f008a544d31f9774ce08d5fd8bc80197 308 Pfam PF01513 ATP-NAD kinase 7 284 1.9E-75 T 06-07-2017 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 BWK49_RS27775 e86c719d3797f3c8f08dd87c562bc131 570 SUPERFAMILY SSF52467 191 353 1.01E-30 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain BWK49_RS27775 e86c719d3797f3c8f08dd87c562bc131 570 SUPERFAMILY SSF52518 369 558 9.24E-35 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS27775 e86c719d3797f3c8f08dd87c562bc131 570 Gene3D G3DSA:3.40.50.1220 192 340 1.9E-31 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain BWK49_RS27775 e86c719d3797f3c8f08dd87c562bc131 570 Gene3D G3DSA:3.40.50.970 8 179 7.7E-42 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS27775 e86c719d3797f3c8f08dd87c562bc131 570 Gene3D G3DSA:3.40.50.970 363 558 1.2E-38 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS27775 e86c719d3797f3c8f08dd87c562bc131 570 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 194 330 1.9E-26 T 06-07-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 BWK49_RS27775 e86c719d3797f3c8f08dd87c562bc131 570 SUPERFAMILY SSF52518 4 183 1.97E-36 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS27775 e86c719d3797f3c8f08dd87c562bc131 570 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 7 172 2.0E-42 T 06-07-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 BWK49_RS27775 e86c719d3797f3c8f08dd87c562bc131 570 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 399 544 1.0E-24 T 06-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 BWK49_RS21875 b382612c68b7c0d1ba7c206b1125bea7 216 Gene3D G3DSA:1.10.10.10 149 207 2.3E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS21875 b382612c68b7c0d1ba7c206b1125bea7 216 Gene3D G3DSA:3.40.50.2300 2 148 2.0E-33 T 06-07-2017 BWK49_RS21875 b382612c68b7c0d1ba7c206b1125bea7 216 SMART SM00421 147 204 7.6E-25 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS21875 b382612c68b7c0d1ba7c206b1125bea7 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 164 1.5E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS21875 b382612c68b7c0d1ba7c206b1125bea7 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 180 1.5E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS21875 b382612c68b7c0d1ba7c206b1125bea7 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 192 1.5E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS21875 b382612c68b7c0d1ba7c206b1125bea7 216 SUPERFAMILY SSF46894 139 208 7.82E-20 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 BWK49_RS21875 b382612c68b7c0d1ba7c206b1125bea7 216 Pfam PF00196 Bacterial regulatory proteins, luxR family 150 204 1.8E-17 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS21875 b382612c68b7c0d1ba7c206b1125bea7 216 ProSitePatterns PS00622 LuxR-type HTH domain signature. 164 191 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS21875 b382612c68b7c0d1ba7c206b1125bea7 216 SMART SM00448 2 115 2.2E-25 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 BWK49_RS21875 b382612c68b7c0d1ba7c206b1125bea7 216 SUPERFAMILY SSF52172 3 129 3.27E-29 T 06-07-2017 IPR011006 CheY-like superfamily BWK49_RS21875 b382612c68b7c0d1ba7c206b1125bea7 216 Pfam PF00072 Response regulator receiver domain 4 115 5.7E-23 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 BWK49_RS03330 81bae69b63917c6d222227b3d67c083c 200 Gene3D G3DSA:1.10.10.60 6 60 1.1E-20 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS03330 81bae69b63917c6d222227b3d67c083c 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 1.4E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS03330 81bae69b63917c6d222227b3d67c083c 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 1.4E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS03330 81bae69b63917c6d222227b3d67c083c 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 61 8.8E-18 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS03330 81bae69b63917c6d222227b3d67c083c 200 SUPERFAMILY SSF48498 82 197 3.18E-21 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS03330 81bae69b63917c6d222227b3d67c083c 200 Gene3D G3DSA:1.10.357.10 61 197 1.3E-42 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS03330 81bae69b63917c6d222227b3d67c083c 200 SUPERFAMILY SSF46689 6 87 1.15E-20 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS25335 706f65f18fc2029a3faebecc1d1d7b36 297 SUPERFAMILY SSF54637 172 293 4.33E-8 T 06-07-2017 IPR029069 HotDog domain BWK49_RS25335 706f65f18fc2029a3faebecc1d1d7b36 297 Gene3D G3DSA:3.10.129.10 33 105 8.3E-9 T 06-07-2017 IPR029069 HotDog domain BWK49_RS25335 706f65f18fc2029a3faebecc1d1d7b36 297 SMART SM00046 65 205 3.7E-8 T 06-07-2017 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 BWK49_RS25335 706f65f18fc2029a3faebecc1d1d7b36 297 Pfam PF13622 Thioesterase-like superfamily 24 293 1.2E-39 T 06-07-2017 BWK49_RS25335 706f65f18fc2029a3faebecc1d1d7b36 297 SUPERFAMILY SSF54637 5 115 1.55E-11 T 06-07-2017 IPR029069 HotDog domain BWK49_RS10510 a328c83475055858e3e58b75f64e04b3 95 SUPERFAMILY SSF54909 4 88 5.03E-6 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel BWK49_RS10510 a328c83475055858e3e58b75f64e04b3 95 Pfam PF07045 Domain of unknown function (DUF1330) 6 90 1.1E-5 T 06-07-2017 IPR010753 Domain of unknown function DUF1330 BWK49_RS10510 a328c83475055858e3e58b75f64e04b3 95 Gene3D G3DSA:3.30.70.900 5 87 2.8E-5 T 06-07-2017 BWK49_RS22485 a328c83475055858e3e58b75f64e04b3 95 SUPERFAMILY SSF54909 4 88 5.03E-6 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel BWK49_RS22485 a328c83475055858e3e58b75f64e04b3 95 Pfam PF07045 Domain of unknown function (DUF1330) 6 90 1.1E-5 T 06-07-2017 IPR010753 Domain of unknown function DUF1330 BWK49_RS22485 a328c83475055858e3e58b75f64e04b3 95 Gene3D G3DSA:3.30.70.900 5 87 2.8E-5 T 06-07-2017 BWK49_RS10375 a328c83475055858e3e58b75f64e04b3 95 SUPERFAMILY SSF54909 4 88 5.03E-6 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel BWK49_RS10375 a328c83475055858e3e58b75f64e04b3 95 Pfam PF07045 Domain of unknown function (DUF1330) 6 90 1.1E-5 T 06-07-2017 IPR010753 Domain of unknown function DUF1330 BWK49_RS10375 a328c83475055858e3e58b75f64e04b3 95 Gene3D G3DSA:3.30.70.900 5 87 2.8E-5 T 06-07-2017 BWK49_RS05025 a328c83475055858e3e58b75f64e04b3 95 SUPERFAMILY SSF54909 4 88 5.03E-6 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel BWK49_RS05025 a328c83475055858e3e58b75f64e04b3 95 Pfam PF07045 Domain of unknown function (DUF1330) 6 90 1.1E-5 T 06-07-2017 IPR010753 Domain of unknown function DUF1330 BWK49_RS05025 a328c83475055858e3e58b75f64e04b3 95 Gene3D G3DSA:3.30.70.900 5 87 2.8E-5 T 06-07-2017 BWK49_RS14660 5ac7e19e700ed06b8e174cbc525c28e1 172 Gene3D G3DSA:3.40.220.10 11 171 3.0E-41 T 06-07-2017 BWK49_RS14660 5ac7e19e700ed06b8e174cbc525c28e1 172 SMART SM00506 11 138 2.0E-38 T 06-07-2017 IPR002589 Macro domain BWK49_RS14660 5ac7e19e700ed06b8e174cbc525c28e1 172 Pfam PF01661 Macro domain 28 138 4.8E-26 T 06-07-2017 IPR002589 Macro domain BWK49_RS14660 5ac7e19e700ed06b8e174cbc525c28e1 172 SUPERFAMILY SSF52949 11 171 6.22E-43 T 06-07-2017 BWK49_RS08420 6e78121814062ff6bc14459dbc10fc72 471 Pfam PF13193 AMP-binding enzyme C-terminal domain 390 461 1.8E-20 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS08420 6e78121814062ff6bc14459dbc10fc72 471 Gene3D G3DSA:2.30.38.10 297 373 1.4E-25 T 06-07-2017 BWK49_RS08420 6e78121814062ff6bc14459dbc10fc72 471 Gene3D G3DSA:3.40.50.980 142 291 1.3E-31 T 06-07-2017 BWK49_RS08420 6e78121814062ff6bc14459dbc10fc72 471 ProSitePatterns PS00455 Putative AMP-binding domain signature. 134 145 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS08420 6e78121814062ff6bc14459dbc10fc72 471 Gene3D G3DSA:3.30.300.30 377 467 6.1E-29 T 06-07-2017 BWK49_RS08420 6e78121814062ff6bc14459dbc10fc72 471 Gene3D G3DSA:3.40.50.980 43 141 1.4E-17 T 06-07-2017 BWK49_RS08420 6e78121814062ff6bc14459dbc10fc72 471 SUPERFAMILY SSF56801 20 468 1.44E-116 T 06-07-2017 BWK49_RS08420 6e78121814062ff6bc14459dbc10fc72 471 Pfam PF00501 AMP-binding enzyme 46 374 9.9E-69 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS03400 7f38f37ace86265953112ec34db2d9a1 387 Gene3D G3DSA:3.40.47.10 184 270 6.8E-57 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS03400 7f38f37ace86265953112ec34db2d9a1 387 Gene3D G3DSA:3.40.47.10 5 124 6.8E-57 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS03400 7f38f37ace86265953112ec34db2d9a1 387 SUPERFAMILY SSF53901 5 264 1.52E-60 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS03400 7f38f37ace86265953112ec34db2d9a1 387 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 385 9.1E-114 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 BWK49_RS03400 7f38f37ace86265953112ec34db2d9a1 387 Pfam PF00108 Thiolase, N-terminal domain 5 257 1.6E-56 T 06-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 BWK49_RS03400 7f38f37ace86265953112ec34db2d9a1 387 ProSitePatterns PS00737 Thiolases signature 2. 333 349 - T 06-07-2017 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 BWK49_RS03400 7f38f37ace86265953112ec34db2d9a1 387 SUPERFAMILY SSF53901 265 386 1.77E-37 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS03400 7f38f37ace86265953112ec34db2d9a1 387 Pfam PF02803 Thiolase, C-terminal domain 265 386 2.7E-38 T 06-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 BWK49_RS03400 7f38f37ace86265953112ec34db2d9a1 387 PIRSF PIRSF000429 1 387 1.7E-118 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 BWK49_RS03400 7f38f37ace86265953112ec34db2d9a1 387 Gene3D G3DSA:3.40.47.10 271 386 6.8E-48 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS03400 7f38f37ace86265953112ec34db2d9a1 387 Gene3D G3DSA:3.40.47.10 148 183 6.8E-48 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS08345 4dc529d01d4ac4d29964b52c60fc7d76 419 Gene3D G3DSA:3.10.400.10 13 179 2.5E-51 T 06-07-2017 BWK49_RS08345 4dc529d01d4ac4d29964b52c60fc7d76 419 Pfam PF14306 PUA-like domain 10 158 2.4E-41 T 06-07-2017 IPR025980 ATP-sulfurylase PUA-like domain KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 BWK49_RS08345 4dc529d01d4ac4d29964b52c60fc7d76 419 Gene3D G3DSA:3.40.50.620 180 389 1.1E-68 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold BWK49_RS08345 4dc529d01d4ac4d29964b52c60fc7d76 419 SUPERFAMILY SSF52374 166 387 7.36E-67 T 06-07-2017 BWK49_RS08345 4dc529d01d4ac4d29964b52c60fc7d76 419 Pfam PF01747 ATP-sulfurylase 168 387 1.4E-74 T 06-07-2017 IPR024951 Sulphate adenylyltransferase catalytic domain GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 BWK49_RS08345 4dc529d01d4ac4d29964b52c60fc7d76 419 TIGRFAM TIGR00339 sopT: sulfate adenylyltransferase 16 387 1.1E-108 T 06-07-2017 IPR002650 Sulphate adenylyltransferase GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 BWK49_RS08345 4dc529d01d4ac4d29964b52c60fc7d76 419 SUPERFAMILY SSF88697 6 163 1.79E-41 T 06-07-2017 IPR015947 PUA-like domain BWK49_RS06030 e898f40fa3013389c0c93e06eaf5ab4e 276 SUPERFAMILY SSF51735 3 245 1.32E-58 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS06030 e898f40fa3013389c0c93e06eaf5ab4e 276 Gene3D G3DSA:3.40.50.720 6 242 4.9E-60 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS06030 e898f40fa3013389c0c93e06eaf5ab4e 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 1.9E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS06030 e898f40fa3013389c0c93e06eaf5ab4e 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 1.9E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS06030 e898f40fa3013389c0c93e06eaf5ab4e 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 1.9E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS06030 e898f40fa3013389c0c93e06eaf5ab4e 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 1.9E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS06030 e898f40fa3013389c0c93e06eaf5ab4e 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.9E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS06030 e898f40fa3013389c0c93e06eaf5ab4e 276 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 8.3E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS06030 e898f40fa3013389c0c93e06eaf5ab4e 276 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 8.3E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS06030 e898f40fa3013389c0c93e06eaf5ab4e 276 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS06030 e898f40fa3013389c0c93e06eaf5ab4e 276 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 187 0.0028 T 06-07-2017 BWK49_RS06030 e898f40fa3013389c0c93e06eaf5ab4e 276 Pfam PF00106 short chain dehydrogenase 9 197 1.4E-45 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS23600 80675c0d11ccd2b20dd4730f819ec5d1 154 SUPERFAMILY SSF75217 4 152 1.18E-39 T 06-07-2017 IPR029028 Alpha/beta knot methyltransferases BWK49_RS23600 80675c0d11ccd2b20dd4730f819ec5d1 154 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 2 151 29.275 T 06-07-2017 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 BWK49_RS23600 80675c0d11ccd2b20dd4730f819ec5d1 154 Gene3D G3DSA:3.40.1280.10 2 153 1.3E-56 T 06-07-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal BWK49_RS23600 80675c0d11ccd2b20dd4730f819ec5d1 154 PIRSF PIRSF029256 1 154 3.1E-56 T 06-07-2017 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 BWK49_RS23600 80675c0d11ccd2b20dd4730f819ec5d1 154 Pfam PF00588 SpoU rRNA Methylase family 4 142 1.1E-28 T 06-07-2017 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 BWK49_RS08315 34aeecacb86185066622d1821c2c14ac 361 Pfam PF00155 Aminotransferase class I and II 27 360 5.4E-38 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 BWK49_RS08315 34aeecacb86185066622d1821c2c14ac 361 SUPERFAMILY SSF53383 4 361 3.06E-74 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase BWK49_RS08315 34aeecacb86185066622d1821c2c14ac 361 Gene3D G3DSA:3.90.1150.10 240 361 1.4E-22 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 BWK49_RS08315 34aeecacb86185066622d1821c2c14ac 361 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 218 231 - T 06-07-2017 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 BWK49_RS08315 34aeecacb86185066622d1821c2c14ac 361 TIGRFAM TIGR03539 DapC_actino: succinyldiaminopimelate transaminase 5 360 1.5E-179 T 06-07-2017 IPR019880 Succinyldiaminopimelate transaminase, DapC, actinobacteria BWK49_RS08315 34aeecacb86185066622d1821c2c14ac 361 Gene3D G3DSA:3.40.640.10 42 239 6.4E-38 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 BWK49_RS09575 d568216226cc5b62da6c075f91f52e81 488 Pfam PF00171 Aldehyde dehydrogenase family 19 478 4.2E-155 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 BWK49_RS09575 d568216226cc5b62da6c075f91f52e81 488 Gene3D G3DSA:3.40.309.10 269 454 2.1E-68 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 BWK49_RS09575 d568216226cc5b62da6c075f91f52e81 488 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 283 294 - T 06-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 BWK49_RS09575 d568216226cc5b62da6c075f91f52e81 488 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 255 262 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 BWK49_RS09575 d568216226cc5b62da6c075f91f52e81 488 Gene3D G3DSA:3.40.605.10 12 268 3.9E-82 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 BWK49_RS09575 d568216226cc5b62da6c075f91f52e81 488 SUPERFAMILY SSF53720 11 480 2.62E-154 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 BWK49_RS28375 dd93620dd09d58dda17e619f7cf2e901 365 Pfam PF02096 60Kd inner membrane protein 41 274 1.2E-48 T 06-07-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 BWK49_RS28375 dd93620dd09d58dda17e619f7cf2e901 365 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 41 274 4.1E-56 T 06-07-2017 IPR028055 Membrane insertase YidC/Oxa1, C-terminal BWK49_RS22650 09cf3a109cb2832da6dfac98c9c0fcea 1041 SUPERFAMILY SSF52540 11 703 4.28E-72 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS22650 09cf3a109cb2832da6dfac98c9c0fcea 1041 Pfam PF00580 UvrD/REP helicase N-terminal domain 17 297 1.8E-26 T 06-07-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 BWK49_RS22650 09cf3a109cb2832da6dfac98c9c0fcea 1041 Pfam PF13361 UvrD-like helicase C-terminal domain 537 679 4.8E-11 T 06-07-2017 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 BWK49_RS22650 09cf3a109cb2832da6dfac98c9c0fcea 1041 Gene3D G3DSA:3.40.50.300 10 149 7.1E-29 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS22650 09cf3a109cb2832da6dfac98c9c0fcea 1041 Gene3D G3DSA:3.40.50.300 193 296 7.1E-29 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS22650 09cf3a109cb2832da6dfac98c9c0fcea 1041 Gene3D G3DSA:3.40.50.300 308 423 5.9E-29 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS22650 09cf3a109cb2832da6dfac98c9c0fcea 1041 Gene3D G3DSA:3.40.50.300 595 701 5.9E-29 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS22650 09cf3a109cb2832da6dfac98c9c0fcea 1041 Pfam PF12705 PD-(D/E)XK nuclease superfamily 790 1033 3.1E-43 T 06-07-2017 BWK49_RS00380 21a1e635f89ddafea513436943050c08 172 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 3 172 6.6E-39 T 06-07-2017 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 BWK49_RS00380 21a1e635f89ddafea513436943050c08 172 Hamap MF_00984 Single-stranded DNA-binding protein. 4 113 32.216 T 06-07-2017 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 BWK49_RS00380 21a1e635f89ddafea513436943050c08 172 SUPERFAMILY SSF50249 6 172 4.93E-50 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS00380 21a1e635f89ddafea513436943050c08 172 Pfam PF00436 Single-strand binding protein family 6 106 7.8E-31 T 06-07-2017 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 BWK49_RS00380 21a1e635f89ddafea513436943050c08 172 Gene3D G3DSA:2.40.50.140 4 118 1.2E-42 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS20770 aa29dad5cafdeed758c4fa54d597044f 563 Pfam PF13684 Dihydroxyacetone kinase family 247 563 4.5E-72 T 06-07-2017 IPR033470 Uncharacterised protein, DhaK domain BWK49_RS20770 aa29dad5cafdeed758c4fa54d597044f 563 TIGRFAM TIGR03599 YloV: DAK2 domain fusion protein YloV 17 563 2.2E-143 T 06-07-2017 IPR019986 DAK2 domain-containing protein YloV BWK49_RS20770 aa29dad5cafdeed758c4fa54d597044f 563 SMART SM01121 246 563 5.0E-88 T 06-07-2017 IPR033470 Uncharacterised protein, DhaK domain BWK49_RS20770 aa29dad5cafdeed758c4fa54d597044f 563 SMART SM01120 42 217 3.0E-40 T 06-07-2017 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 BWK49_RS20770 aa29dad5cafdeed758c4fa54d597044f 563 Pfam PF02734 DAK2 domain 42 216 3.8E-29 T 06-07-2017 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 BWK49_RS20770 aa29dad5cafdeed758c4fa54d597044f 563 SUPERFAMILY SSF101473 12 217 1.44E-28 T 06-07-2017 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 BWK49_RS04130 2e84858eab192a119e53fa8b4eb3c920 383 PIRSF PIRSF002756 17 383 9.7E-119 T 06-07-2017 IPR005673 ABC transporter, phosphate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 BWK49_RS04130 2e84858eab192a119e53fa8b4eb3c920 383 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 65 381 5.9E-83 T 06-07-2017 IPR005673 ABC transporter, phosphate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 BWK49_RS04130 2e84858eab192a119e53fa8b4eb3c920 383 Gene3D G3DSA:3.40.190.10 235 379 1.5E-21 T 06-07-2017 BWK49_RS04130 2e84858eab192a119e53fa8b4eb3c920 383 Gene3D G3DSA:3.40.190.10 63 218 6.1E-40 T 06-07-2017 BWK49_RS04130 2e84858eab192a119e53fa8b4eb3c920 383 SUPERFAMILY SSF53850 65 382 6.21E-81 T 06-07-2017 BWK49_RS04130 2e84858eab192a119e53fa8b4eb3c920 383 Pfam PF12849 PBP superfamily domain 62 349 1.5E-54 T 06-07-2017 IPR024370 PBP domain BWK49_RS09970 2e720630352a69dcde93c9a2c8813578 489 Gene3D G3DSA:3.90.190.20 337 486 2.4E-37 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 BWK49_RS09970 2e720630352a69dcde93c9a2c8813578 489 Gene3D G3DSA:3.40.1190.10 41 334 1.1E-90 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 BWK49_RS09970 2e720630352a69dcde93c9a2c8813578 489 Pfam PF02875 Mur ligase family, glutamate ligase domain 336 413 1.2E-9 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 BWK49_RS09970 2e720630352a69dcde93c9a2c8813578 489 SUPERFAMILY SSF53623 31 333 3.26E-82 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 BWK49_RS09970 2e720630352a69dcde93c9a2c8813578 489 ProSitePatterns PS01012 Folylpolyglutamate synthase signature 2. 172 187 - T 06-07-2017 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 BWK49_RS09970 2e720630352a69dcde93c9a2c8813578 489 Pfam PF08245 Mur ligase middle domain 72 309 1.0E-14 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 BWK49_RS09970 2e720630352a69dcde93c9a2c8813578 489 SUPERFAMILY SSF53244 337 485 9.89E-24 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 BWK49_RS09970 2e720630352a69dcde93c9a2c8813578 489 TIGRFAM TIGR01499 folC: bifunctional protein FolC 50 482 7.7E-92 T 06-07-2017 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 BWK49_RS22930 a3a798e48c8f469ec9b1dd7fed52ffb7 228 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 224 8.2E-26 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 BWK49_RS22930 a3a798e48c8f469ec9b1dd7fed52ffb7 228 SMART SM00448 6 116 1.1E-44 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 BWK49_RS22930 a3a798e48c8f469ec9b1dd7fed52ffb7 228 SUPERFAMILY SSF52172 6 182 4.27E-44 T 06-07-2017 IPR011006 CheY-like superfamily BWK49_RS22930 a3a798e48c8f469ec9b1dd7fed52ffb7 228 SMART SM00862 149 225 2.6E-24 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 BWK49_RS22930 a3a798e48c8f469ec9b1dd7fed52ffb7 228 Gene3D G3DSA:3.40.50.2300 4 125 4.3E-40 T 06-07-2017 BWK49_RS22930 a3a798e48c8f469ec9b1dd7fed52ffb7 228 Pfam PF00072 Response regulator receiver domain 8 117 3.1E-29 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 BWK49_RS22930 a3a798e48c8f469ec9b1dd7fed52ffb7 228 Gene3D G3DSA:1.10.10.10 127 225 7.9E-34 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS18570 7d56ad45c888824906639a9b7abfd1f4 144 Pfam PF01220 Dehydroquinase class II 5 140 1.2E-52 T 06-07-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 BWK49_RS18570 7d56ad45c888824906639a9b7abfd1f4 144 TIGRFAM TIGR01088 aroQ: 3-dehydroquinate dehydratase, type II 5 141 9.0E-61 T 06-07-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 BWK49_RS18570 7d56ad45c888824906639a9b7abfd1f4 144 ProSitePatterns PS01029 Dehydroquinase class II signature. 8 25 - T 06-07-2017 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 BWK49_RS18570 7d56ad45c888824906639a9b7abfd1f4 144 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 5 132 5.0E-63 T 06-07-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 BWK49_RS18570 7d56ad45c888824906639a9b7abfd1f4 144 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 144 61.716 T 06-07-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 BWK49_RS18570 7d56ad45c888824906639a9b7abfd1f4 144 Gene3D G3DSA:3.40.50.9100 2 142 4.8E-57 T 06-07-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 BWK49_RS18570 7d56ad45c888824906639a9b7abfd1f4 144 PIRSF PIRSF001399 1 143 5.7E-56 T 06-07-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 BWK49_RS18570 7d56ad45c888824906639a9b7abfd1f4 144 SUPERFAMILY SSF52304 2 141 1.11E-53 T 06-07-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 BWK49_RS16280 60090bd9bf5553ad62c7fe9f75366618 496 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 2 491 1.3E-142 T 06-07-2017 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS16280 60090bd9bf5553ad62c7fe9f75366618 496 Pfam PF00361 Proton-conducting membrane transporter 126 422 8.3E-63 T 06-07-2017 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS16280 60090bd9bf5553ad62c7fe9f75366618 496 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 132 151 1.5E-26 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS16280 60090bd9bf5553ad62c7fe9f75366618 496 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 386 412 1.5E-26 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS16280 60090bd9bf5553ad62c7fe9f75366618 496 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 162 186 1.5E-26 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS16280 60090bd9bf5553ad62c7fe9f75366618 496 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 236 260 1.5E-26 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS01810 8bc901323a966abd9cf31cabf1c63571 296 ProSitePatterns PS00082 Extradiol ring-cleavage dioxygenases signature. 233 254 - T 06-07-2017 IPR000486 Extradiol ring-cleavage dioxygenase, class I /II GO:0003824|GO:0006725|GO:0008198|GO:0055114 BWK49_RS01810 8bc901323a966abd9cf31cabf1c63571 296 Gene3D G3DSA:3.10.180.10 3 131 1.8E-31 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS01810 8bc901323a966abd9cf31cabf1c63571 296 SUPERFAMILY SSF54593 4 263 3.0E-39 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS01810 8bc901323a966abd9cf31cabf1c63571 296 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 142 255 1.1E-20 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain BWK49_RS01810 8bc901323a966abd9cf31cabf1c63571 296 Gene3D G3DSA:3.10.180.10 134 286 4.0E-59 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS23795 964b19959fef7c9be4ff8d4f0b9cbf71 165 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 77 146 2.1E-8 T 06-07-2017 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 BWK49_RS23795 964b19959fef7c9be4ff8d4f0b9cbf71 165 SUPERFAMILY SSF54534 76 147 3.53E-9 T 06-07-2017 BWK49_RS23795 964b19959fef7c9be4ff8d4f0b9cbf71 165 Gene3D G3DSA:3.10.50.30 76 154 8.7E-12 T 06-07-2017 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 BWK49_RS23795 964b19959fef7c9be4ff8d4f0b9cbf71 165 PIRSF PIRSF006092 1 151 2.0E-13 T 06-07-2017 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 BWK49_RS01140 0c47cefd9bddc485f89b5c4803da9c01 169 Gene3D G3DSA:1.20.144.10 8 157 7.1E-25 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase BWK49_RS01140 0c47cefd9bddc485f89b5c4803da9c01 169 SUPERFAMILY SSF48317 3 157 2.22E-32 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase BWK49_RS01140 0c47cefd9bddc485f89b5c4803da9c01 169 SMART SM00014 52 156 2.7E-10 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase BWK49_RS01140 0c47cefd9bddc485f89b5c4803da9c01 169 Pfam PF01569 PAP2 superfamily 59 158 2.5E-14 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase BWK49_RS20165 bbbbbcfdad7ef6a7b27becbb80cc7fec 496 SUPERFAMILY SSF81342 89 238 7.06E-22 T 06-07-2017 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 BWK49_RS20165 bbbbbcfdad7ef6a7b27becbb80cc7fec 496 SUPERFAMILY SSF81342 3 51 7.06E-22 T 06-07-2017 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 BWK49_RS20165 bbbbbcfdad7ef6a7b27becbb80cc7fec 496 Pfam PF01292 Prokaryotic cytochrome b561 6 235 5.5E-43 T 06-07-2017 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 BWK49_RS20165 bbbbbcfdad7ef6a7b27becbb80cc7fec 496 Pfam PF00174 Oxidoreductase molybdopterin binding domain 325 473 4.5E-32 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 BWK49_RS20165 bbbbbcfdad7ef6a7b27becbb80cc7fec 496 SUPERFAMILY SSF56524 320 489 5.76E-49 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 BWK49_RS20165 bbbbbcfdad7ef6a7b27becbb80cc7fec 496 Gene3D G3DSA:3.90.420.10 316 481 2.6E-49 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 BWK49_RS20165 bbbbbcfdad7ef6a7b27becbb80cc7fec 496 Gene3D G3DSA:1.20.950.20 74 238 3.5E-21 T 06-07-2017 BWK49_RS20165 bbbbbcfdad7ef6a7b27becbb80cc7fec 496 Gene3D G3DSA:1.20.950.20 3 36 3.5E-21 T 06-07-2017 BWK49_RS06655 5298bad2cf0ac89c00f8bd941d77e9e7 281 Gene3D G3DSA:3.30.1330.30 11 109 2.4E-10 T 06-07-2017 IPR029064 50S ribosomal protein L30e-like BWK49_RS06655 5298bad2cf0ac89c00f8bd941d77e9e7 281 Pfam PF00588 SpoU rRNA Methylase family 125 268 2.7E-29 T 06-07-2017 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 BWK49_RS06655 5298bad2cf0ac89c00f8bd941d77e9e7 281 Gene3D G3DSA:3.40.1280.10 121 271 5.6E-44 T 06-07-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal BWK49_RS06655 5298bad2cf0ac89c00f8bd941d77e9e7 281 SUPERFAMILY SSF75217 102 274 1.18E-36 T 06-07-2017 IPR029028 Alpha/beta knot methyltransferases BWK49_RS06655 5298bad2cf0ac89c00f8bd941d77e9e7 281 SUPERFAMILY SSF55315 11 109 1.32E-10 T 06-07-2017 IPR029064 50S ribosomal protein L30e-like BWK49_RS07985 38d0a75641242258a99f0a527254ff47 162 SUPERFAMILY SSF54593 3 154 2.92E-46 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS07985 38d0a75641242258a99f0a527254ff47 162 PIRSF PIRSF021700 1 156 3.8E-60 T 06-07-2017 IPR009725 Predicted 3-demethylubiquinone-9 3-methyltransferase BWK49_RS07985 38d0a75641242258a99f0a527254ff47 162 Gene3D G3DSA:3.10.180.10 1 128 2.5E-43 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS07985 38d0a75641242258a99f0a527254ff47 162 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 3 116 1.9E-46 T 06-07-2017 IPR028973 PhnB-like BWK49_RS05210 99f4b3e7fc15b4e4b488ea5b9a116e45 278 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 166 185 3.4E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05210 99f4b3e7fc15b4e4b488ea5b9a116e45 278 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 154 3.4E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05210 99f4b3e7fc15b4e4b488ea5b9a116e45 278 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 92 103 3.4E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05210 99f4b3e7fc15b4e4b488ea5b9a116e45 278 SUPERFAMILY SSF51735 18 270 1.07E-60 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS05210 99f4b3e7fc15b4e4b488ea5b9a116e45 278 Pfam PF00106 short chain dehydrogenase 18 206 4.6E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05210 99f4b3e7fc15b4e4b488ea5b9a116e45 278 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 153 181 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS05210 99f4b3e7fc15b4e4b488ea5b9a116e45 278 Gene3D G3DSA:3.40.50.720 18 270 2.8E-60 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS05210 99f4b3e7fc15b4e4b488ea5b9a116e45 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 187 204 1.8E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05210 99f4b3e7fc15b4e4b488ea5b9a116e45 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 156 1.8E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05210 99f4b3e7fc15b4e4b488ea5b9a116e45 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 185 1.8E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05210 99f4b3e7fc15b4e4b488ea5b9a116e45 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 17 34 1.8E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05210 99f4b3e7fc15b4e4b488ea5b9a116e45 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 92 103 1.8E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS24170 04079d11c4a59ec5e7236f21b330d478 217 SMART SM01007 9 187 2.1E-53 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal BWK49_RS24170 04079d11c4a59ec5e7236f21b330d478 217 Gene3D G3DSA:3.40.225.10 8 201 3.6E-57 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal BWK49_RS24170 04079d11c4a59ec5e7236f21b330d478 217 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 11 186 1.7E-44 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal BWK49_RS24170 04079d11c4a59ec5e7236f21b330d478 217 SUPERFAMILY SSF53639 11 211 1.18E-56 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal BWK49_RS11020 1c646a2723c35f444b3d2ba25dc38b3e 252 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 247 4.6E-52 T 06-07-2017 BWK49_RS11020 1c646a2723c35f444b3d2ba25dc38b3e 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 4.0E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS11020 1c646a2723c35f444b3d2ba25dc38b3e 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 4.0E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS11020 1c646a2723c35f444b3d2ba25dc38b3e 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 4.0E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS11020 1c646a2723c35f444b3d2ba25dc38b3e 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 4.0E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS11020 1c646a2723c35f444b3d2ba25dc38b3e 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 4.0E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS11020 1c646a2723c35f444b3d2ba25dc38b3e 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 4.0E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS11020 1c646a2723c35f444b3d2ba25dc38b3e 252 Gene3D G3DSA:3.40.50.720 1 249 4.3E-68 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS11020 1c646a2723c35f444b3d2ba25dc38b3e 252 SUPERFAMILY SSF51735 7 248 1.58E-64 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS09505 2bbfb14c4d5e4bc4e92452d38b4e372f 382 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 231 377 4.4E-18 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS09505 2bbfb14c4d5e4bc4e92452d38b4e372f 382 Gene3D G3DSA:2.40.110.10 124 220 6.4E-31 T 06-07-2017 BWK49_RS09505 2bbfb14c4d5e4bc4e92452d38b4e372f 382 SUPERFAMILY SSF56645 2 241 3.27E-64 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS09505 2bbfb14c4d5e4bc4e92452d38b4e372f 382 Gene3D G3DSA:1.20.140.10 221 379 1.3E-21 T 06-07-2017 BWK49_RS09505 2bbfb14c4d5e4bc4e92452d38b4e372f 382 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 125 218 7.2E-19 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 BWK49_RS09505 2bbfb14c4d5e4bc4e92452d38b4e372f 382 Gene3D G3DSA:1.10.540.10 1 122 5.1E-20 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS09505 2bbfb14c4d5e4bc4e92452d38b4e372f 382 SUPERFAMILY SSF47203 231 379 3.38E-16 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS09505 2bbfb14c4d5e4bc4e92452d38b4e372f 382 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 121 6.8E-16 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS28020 16849dbe84bb20692421ce5ee209897f 321 Gene3D G3DSA:1.10.10.10 1 79 6.2E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS28020 16849dbe84bb20692421ce5ee209897f 321 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 1.7E-23 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 BWK49_RS28020 16849dbe84bb20692421ce5ee209897f 321 Pfam PF03466 LysR substrate binding domain 94 285 7.1E-32 T 06-07-2017 IPR005119 LysR, substrate-binding BWK49_RS28020 16849dbe84bb20692421ce5ee209897f 321 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.9E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 BWK49_RS28020 16849dbe84bb20692421ce5ee209897f 321 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.9E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 BWK49_RS28020 16849dbe84bb20692421ce5ee209897f 321 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.9E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 BWK49_RS28020 16849dbe84bb20692421ce5ee209897f 321 Gene3D G3DSA:3.40.190.10 178 263 2.7E-15 T 06-07-2017 BWK49_RS28020 16849dbe84bb20692421ce5ee209897f 321 SUPERFAMILY SSF46785 1 82 1.54E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS28020 16849dbe84bb20692421ce5ee209897f 321 SUPERFAMILY SSF53850 93 285 3.57E-29 T 06-07-2017 BWK49_RS28020 16849dbe84bb20692421ce5ee209897f 321 Gene3D G3DSA:3.40.190.10 89 177 7.5E-10 T 06-07-2017 BWK49_RS15780 d70a4f04dec7c360d7df7e0a0c9e77de 412 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 9 240 3.9E-43 T 06-07-2017 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 BWK49_RS15780 d70a4f04dec7c360d7df7e0a0c9e77de 412 SUPERFAMILY SSF51395 298 383 9.69E-85 T 06-07-2017 BWK49_RS15780 d70a4f04dec7c360d7df7e0a0c9e77de 412 SUPERFAMILY SSF51395 9 263 9.69E-85 T 06-07-2017 BWK49_RS15780 d70a4f04dec7c360d7df7e0a0c9e77de 412 Gene3D G3DSA:3.20.20.70 9 260 1.3E-89 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 BWK49_RS15780 d70a4f04dec7c360d7df7e0a0c9e77de 412 Gene3D G3DSA:3.20.20.70 301 392 1.3E-89 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 BWK49_RS17425 ee432d4fb8d2996f6eae37087509c5dc 226 PIRSF PIRSF006755 1 196 4.4E-35 T 06-07-2017 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 BWK49_RS17425 ee432d4fb8d2996f6eae37087509c5dc 226 TIGRFAM TIGR00347 bioD: dethiobiotin synthase 6 168 1.7E-31 T 06-07-2017 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 BWK49_RS17425 ee432d4fb8d2996f6eae37087509c5dc 226 Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. 1 202 22.88 T 06-07-2017 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 BWK49_RS17425 ee432d4fb8d2996f6eae37087509c5dc 226 Gene3D G3DSA:3.40.50.300 3 197 1.8E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS17425 ee432d4fb8d2996f6eae37087509c5dc 226 SUPERFAMILY SSF52540 3 174 5.8E-37 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS17425 ee432d4fb8d2996f6eae37087509c5dc 226 Pfam PF13500 AAA domain 4 192 4.8E-31 T 06-07-2017 BWK49_RS01660 ed470ed49ead282cfccfa630d1d4dd7b 354 Pfam PF01548 Transposase 4 154 1.3E-22 T 06-07-2017 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 BWK49_RS01660 ed470ed49ead282cfccfa630d1d4dd7b 354 Pfam PF02371 Transposase IS116/IS110/IS902 family 224 304 2.1E-18 T 06-07-2017 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 BWK49_RS01920 ed470ed49ead282cfccfa630d1d4dd7b 354 Pfam PF01548 Transposase 4 154 1.3E-22 T 06-07-2017 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 BWK49_RS01920 ed470ed49ead282cfccfa630d1d4dd7b 354 Pfam PF02371 Transposase IS116/IS110/IS902 family 224 304 2.1E-18 T 06-07-2017 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 BWK49_RS03490 722daf0d2aa0a3fa6bf0bb448d68ae88 385 Gene3D G3DSA:2.102.10.10 24 139 1.8E-31 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS03490 722daf0d2aa0a3fa6bf0bb448d68ae88 385 SUPERFAMILY SSF55961 124 345 9.52E-31 T 06-07-2017 BWK49_RS03490 722daf0d2aa0a3fa6bf0bb448d68ae88 385 SUPERFAMILY SSF50022 20 131 1.31E-28 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS03490 722daf0d2aa0a3fa6bf0bb448d68ae88 385 Pfam PF00355 Rieske [2Fe-2S] domain 26 109 9.8E-18 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS26440 2e777569026ac06540399a7ececad982 487 SUPERFAMILY SSF140459 1 171 2.62E-58 T 06-07-2017 BWK49_RS26440 2e777569026ac06540399a7ececad982 487 Pfam PF00823 PPE family 2 158 2.9E-61 T 06-07-2017 IPR000030 PPE family BWK49_RS22895 c4d997043b571236ae6ca782ad95d35c 518 SUPERFAMILY SSF109604 269 436 1.13E-19 T 06-07-2017 BWK49_RS22895 c4d997043b571236ae6ca782ad95d35c 518 Pfam PF00196 Bacterial regulatory proteins, luxR family 452 507 3.4E-16 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS22895 c4d997043b571236ae6ca782ad95d35c 518 Gene3D G3DSA:1.10.10.10 441 513 5.1E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS22895 c4d997043b571236ae6ca782ad95d35c 518 Gene3D G3DSA:1.10.3210.10 266 407 6.1E-12 T 06-07-2017 IPR006674 HD domain BWK49_RS22895 c4d997043b571236ae6ca782ad95d35c 518 SUPERFAMILY SSF46894 442 514 3.4E-21 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 BWK49_RS22895 c4d997043b571236ae6ca782ad95d35c 518 SMART SM00421 450 507 1.2E-21 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS22895 c4d997043b571236ae6ca782ad95d35c 518 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 467 483 8.3E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS22895 c4d997043b571236ae6ca782ad95d35c 518 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 453 467 8.3E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS22895 c4d997043b571236ae6ca782ad95d35c 518 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 483 495 8.3E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS22895 c4d997043b571236ae6ca782ad95d35c 518 Pfam PF13487 HD domain 131 184 2.7E-8 T 06-07-2017 BWK49_RS22895 c4d997043b571236ae6ca782ad95d35c 518 Pfam PF13487 HD domain 328 390 6.4E-15 T 06-07-2017 BWK49_RS11985 0663f98195b589452ecd01183b1bbd68 513 SUPERFAMILY SSF56801 6 511 4.19E-116 T 06-07-2017 BWK49_RS11985 0663f98195b589452ecd01183b1bbd68 513 Gene3D G3DSA:2.30.38.10 336 407 2.0E-23 T 06-07-2017 BWK49_RS11985 0663f98195b589452ecd01183b1bbd68 513 Gene3D G3DSA:3.40.50.980 6 174 1.1E-22 T 06-07-2017 BWK49_RS11985 0663f98195b589452ecd01183b1bbd68 513 Pfam PF00501 AMP-binding enzyme 14 417 5.4E-71 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS11985 0663f98195b589452ecd01183b1bbd68 513 Gene3D G3DSA:3.30.300.30 412 510 1.0E-28 T 06-07-2017 BWK49_RS11985 0663f98195b589452ecd01183b1bbd68 513 Gene3D G3DSA:3.40.50.980 175 326 3.1E-23 T 06-07-2017 BWK49_RS11985 0663f98195b589452ecd01183b1bbd68 513 Pfam PF13193 AMP-binding enzyme C-terminal domain 426 502 3.3E-20 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS25195 88f63ca91d243d853dc89bbe5b5252c6 452 PIRSF PIRSF006060 2 447 2.4E-71 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 BWK49_RS25195 88f63ca91d243d853dc89bbe5b5252c6 452 Pfam PF00324 Amino acid permease 16 422 7.2E-109 T 06-07-2017 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 BWK49_RS25195 88f63ca91d243d853dc89bbe5b5252c6 452 ProSitePatterns PS00218 Amino acid permeases signature. 40 70 - T 06-07-2017 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 BWK49_RS16415 c75a510916a7d2e01bc39551a09a9957 1676 SUPERFAMILY SSF52777 221 465 3.0E-45 T 06-07-2017 BWK49_RS16415 c75a510916a7d2e01bc39551a09a9957 1676 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 517 908 4.3E-131 T 06-07-2017 IPR010071 Amino acid adenylation domain BWK49_RS16415 c75a510916a7d2e01bc39551a09a9957 1676 SUPERFAMILY SSF52777 1106 1276 4.45E-45 T 06-07-2017 BWK49_RS16415 c75a510916a7d2e01bc39551a09a9957 1676 Gene3D G3DSA:3.30.300.30 879 998 2.3E-37 T 06-07-2017 BWK49_RS16415 c75a510916a7d2e01bc39551a09a9957 1676 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1019 1034 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site BWK49_RS16415 c75a510916a7d2e01bc39551a09a9957 1676 SMART SM01294 1570 1633 0.0065 T 06-07-2017 BWK49_RS16415 c75a510916a7d2e01bc39551a09a9957 1676 ProSitePatterns PS00455 Putative AMP-binding domain signature. 629 640 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS16415 c75a510916a7d2e01bc39551a09a9957 1676 Gene3D G3DSA:3.40.50.980 490 637 2.4E-47 T 06-07-2017 BWK49_RS16415 c75a510916a7d2e01bc39551a09a9957 1676 SUPERFAMILY SSF47336 987 1061 1.96E-20 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS16415 c75a510916a7d2e01bc39551a09a9957 1676 Gene3D G3DSA:3.40.50.980 638 796 9.2E-44 T 06-07-2017 BWK49_RS16415 c75a510916a7d2e01bc39551a09a9957 1676 SUPERFAMILY SSF52777 1284 1537 5.63E-47 T 06-07-2017 BWK49_RS16415 c75a510916a7d2e01bc39551a09a9957 1676 Pfam PF00668 Condensation domain 41 328 1.3E-51 T 06-07-2017 IPR001242 Condensation domain BWK49_RS16415 c75a510916a7d2e01bc39551a09a9957 1676 Pfam PF00668 Condensation domain 1104 1394 7.8E-58 T 06-07-2017 IPR001242 Condensation domain BWK49_RS16415 c75a510916a7d2e01bc39551a09a9957 1676 Pfam PF00501 AMP-binding enzyme 497 884 2.7E-93 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS16415 c75a510916a7d2e01bc39551a09a9957 1676 SUPERFAMILY SSF56801 456 1007 5.1E-153 T 06-07-2017 BWK49_RS16415 c75a510916a7d2e01bc39551a09a9957 1676 Pfam PF00550 Phosphopantetheine attachment site 1572 1633 3.3E-9 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS16415 c75a510916a7d2e01bc39551a09a9957 1676 Pfam PF00550 Phosphopantetheine attachment site 997 1060 5.8E-14 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS16415 c75a510916a7d2e01bc39551a09a9957 1676 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1593 1608 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site BWK49_RS16415 c75a510916a7d2e01bc39551a09a9957 1676 Gene3D G3DSA:2.30.38.10 797 874 3.3E-24 T 06-07-2017 BWK49_RS16415 c75a510916a7d2e01bc39551a09a9957 1676 Gene3D G3DSA:1.10.1200.10 999 1063 1.7E-27 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS16415 c75a510916a7d2e01bc39551a09a9957 1676 Gene3D G3DSA:1.10.1200.10 1560 1638 2.8E-16 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS16415 c75a510916a7d2e01bc39551a09a9957 1676 Pfam PF13745 HxxPF-repeated domain 1417 1511 7.9E-19 T 06-07-2017 BWK49_RS16415 c75a510916a7d2e01bc39551a09a9957 1676 Pfam PF13745 HxxPF-repeated domain 351 443 4.6E-11 T 06-07-2017 BWK49_RS16415 c75a510916a7d2e01bc39551a09a9957 1676 SUPERFAMILY SSF52777 44 216 6.45E-40 T 06-07-2017 BWK49_RS16415 c75a510916a7d2e01bc39551a09a9957 1676 Pfam PF13193 AMP-binding enzyme C-terminal domain 892 970 2.6E-13 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS16415 c75a510916a7d2e01bc39551a09a9957 1676 SUPERFAMILY SSF47336 1567 1633 5.89E-12 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS16415 c75a510916a7d2e01bc39551a09a9957 1676 SMART SM00823 Phosphopantetheine attachment site 992 1064 3.4E-9 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS16415 c75a510916a7d2e01bc39551a09a9957 1676 SMART SM00823 Phosphopantetheine attachment site 1572 1637 0.0025 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS06720 e5ecaa15824bfcd1347871c10bc35b84 445 SMART SM00387 337 445 4.5E-26 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS06720 e5ecaa15824bfcd1347871c10bc35b84 445 SUPERFAMILY SSF47384 214 291 4.9E-11 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 BWK49_RS06720 e5ecaa15824bfcd1347871c10bc35b84 445 SUPERFAMILY SSF55874 302 442 7.07E-29 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS06720 e5ecaa15824bfcd1347871c10bc35b84 445 Pfam PF00672 HAMP domain 151 216 9.3E-9 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 BWK49_RS06720 e5ecaa15824bfcd1347871c10bc35b84 445 SMART SM00388 229 295 1.2E-11 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 BWK49_RS06720 e5ecaa15824bfcd1347871c10bc35b84 445 Gene3D G3DSA:3.30.565.10 301 443 1.7E-29 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS06720 e5ecaa15824bfcd1347871c10bc35b84 445 PRINTS PR00344 Bacterial sensor protein C-terminal signature 373 387 3.5E-11 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 BWK49_RS06720 e5ecaa15824bfcd1347871c10bc35b84 445 PRINTS PR00344 Bacterial sensor protein C-terminal signature 429 442 3.5E-11 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 BWK49_RS06720 e5ecaa15824bfcd1347871c10bc35b84 445 PRINTS PR00344 Bacterial sensor protein C-terminal signature 405 423 3.5E-11 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 BWK49_RS06720 e5ecaa15824bfcd1347871c10bc35b84 445 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 339 442 1.7E-19 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS06720 e5ecaa15824bfcd1347871c10bc35b84 445 Gene3D G3DSA:1.10.287.130 221 286 1.1E-9 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 BWK49_RS06720 e5ecaa15824bfcd1347871c10bc35b84 445 Pfam PF00512 His Kinase A (phospho-acceptor) domain 231 291 1.0E-10 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 BWK49_RS08180 2f3bd8f8a5cb1cf0c0562cf20f3cf2a6 237 Hamap MF_01121 NAD-dependent protein deacylase [cobB]. 1 234 61.56 T 06-07-2017 IPR027546 Sirtuin, class III GO:0036054|GO:0036055|GO:0070403 BWK49_RS08180 2f3bd8f8a5cb1cf0c0562cf20f3cf2a6 237 Gene3D G3DSA:3.40.50.1220 65 105 2.8E-40 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain BWK49_RS08180 2f3bd8f8a5cb1cf0c0562cf20f3cf2a6 237 Gene3D G3DSA:3.40.50.1220 2 16 2.8E-40 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain BWK49_RS08180 2f3bd8f8a5cb1cf0c0562cf20f3cf2a6 237 Gene3D G3DSA:3.40.50.1220 163 229 2.8E-40 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain BWK49_RS08180 2f3bd8f8a5cb1cf0c0562cf20f3cf2a6 237 Gene3D G3DSA:3.30.1600.10 106 154 6.1E-22 T 06-07-2017 IPR026591 Sirtuin family, catalytic core small domain BWK49_RS08180 2f3bd8f8a5cb1cf0c0562cf20f3cf2a6 237 Gene3D G3DSA:3.30.1600.10 17 57 6.1E-22 T 06-07-2017 IPR026591 Sirtuin family, catalytic core small domain BWK49_RS08180 2f3bd8f8a5cb1cf0c0562cf20f3cf2a6 237 SUPERFAMILY SSF52467 2 232 9.27E-76 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain BWK49_RS08180 2f3bd8f8a5cb1cf0c0562cf20f3cf2a6 237 Pfam PF02146 Sir2 family 8 184 8.7E-54 T 06-07-2017 IPR003000 Sirtuin family GO:0070403 BWK49_RS25940 d0e0dc689764e9e1c0e235efc797682c 293 SUPERFAMILY SSF53335 7 273 1.58E-56 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS25940 d0e0dc689764e9e1c0e235efc797682c 293 Gene3D G3DSA:3.40.50.150 72 193 1.7E-13 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS25940 d0e0dc689764e9e1c0e235efc797682c 293 Pfam PF04072 Leucine carboxyl methyltransferase 11 191 1.3E-51 T 06-07-2017 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 BWK49_RS25940 d0e0dc689764e9e1c0e235efc797682c 293 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 10 268 8.9E-66 T 06-07-2017 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 BWK49_RS20260 d859d36ab8c4a5cb7b88855d3931198a 252 Pfam PF13185 GAF domain 32 171 8.9E-8 T 06-07-2017 IPR003018 GAF domain GO:0005515 BWK49_RS20260 d859d36ab8c4a5cb7b88855d3931198a 252 Gene3D G3DSA:3.30.450.40 20 172 8.4E-11 T 06-07-2017 IPR029016 GAF domain-like BWK49_RS20260 d859d36ab8c4a5cb7b88855d3931198a 252 SUPERFAMILY SSF52172 174 234 8.95E-9 T 06-07-2017 IPR011006 CheY-like superfamily BWK49_RS20260 d859d36ab8c4a5cb7b88855d3931198a 252 SUPERFAMILY SSF55781 18 172 6.73E-13 T 06-07-2017 IPR029016 GAF domain-like BWK49_RS20260 d859d36ab8c4a5cb7b88855d3931198a 252 PIRSF PIRSF036625 2 245 1.1E-71 T 06-07-2017 IPR012074 GAF-ANTAR transcription anti-termination regulator, putative BWK49_RS20260 d859d36ab8c4a5cb7b88855d3931198a 252 Gene3D G3DSA:1.10.10.10 182 240 3.0E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS20260 d859d36ab8c4a5cb7b88855d3931198a 252 SMART SM01012 179 234 4.0E-19 T 06-07-2017 IPR005561 ANTAR domain GO:0003723 BWK49_RS20260 d859d36ab8c4a5cb7b88855d3931198a 252 Pfam PF03861 ANTAR domain 182 234 6.1E-16 T 06-07-2017 IPR005561 ANTAR domain GO:0003723 BWK49_RS19415 643c1aa4488a403b8839e45bac193c4c 292 Pfam PF00459 Inositol monophosphatase family 15 274 2.5E-61 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 BWK49_RS19415 643c1aa4488a403b8839e45bac193c4c 292 Gene3D G3DSA:3.40.190.80 181 283 3.3E-32 T 06-07-2017 BWK49_RS19415 643c1aa4488a403b8839e45bac193c4c 292 SUPERFAMILY SSF56655 10 282 1.7E-67 T 06-07-2017 BWK49_RS19415 643c1aa4488a403b8839e45bac193c4c 292 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 104 117 - T 06-07-2017 IPR020583 Inositol monophosphatase, metal-binding site BWK49_RS19415 643c1aa4488a403b8839e45bac193c4c 292 PRINTS PR00377 Inositol monophosphatase superfamily signature 79 95 1.2E-28 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 BWK49_RS19415 643c1aa4488a403b8839e45bac193c4c 292 PRINTS PR00377 Inositol monophosphatase superfamily signature 234 258 1.2E-28 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 BWK49_RS19415 643c1aa4488a403b8839e45bac193c4c 292 PRINTS PR00377 Inositol monophosphatase superfamily signature 104 120 1.2E-28 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 BWK49_RS19415 643c1aa4488a403b8839e45bac193c4c 292 PRINTS PR00377 Inositol monophosphatase superfamily signature 203 224 1.2E-28 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 BWK49_RS19415 643c1aa4488a403b8839e45bac193c4c 292 PRINTS PR00377 Inositol monophosphatase superfamily signature 57 77 1.2E-28 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 BWK49_RS19415 643c1aa4488a403b8839e45bac193c4c 292 Gene3D G3DSA:3.30.540.10 10 180 1.8E-41 T 06-07-2017 BWK49_RS19415 643c1aa4488a403b8839e45bac193c4c 292 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 237 251 - T 06-07-2017 IPR020550 Inositol monophosphatase, conserved site GO:0046854 BWK49_RS06905 2889672ab32dbd67321adb8ea27ae0d1 305 Gene3D G3DSA:3.40.50.150 16 194 1.4E-12 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS06905 2889672ab32dbd67321adb8ea27ae0d1 305 Pfam PF04072 Leucine carboxyl methyltransferase 19 201 4.8E-63 T 06-07-2017 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 BWK49_RS06905 2889672ab32dbd67321adb8ea27ae0d1 305 SUPERFAMILY SSF53335 15 283 1.66E-68 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS06905 2889672ab32dbd67321adb8ea27ae0d1 305 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 17 276 6.3E-75 T 06-07-2017 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 BWK49_RS16440 fc537c61843ae0e8de8221fb493424ae 68 Pfam PF00403 Heavy-metal-associated domain 5 65 1.4E-15 T 06-07-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 BWK49_RS16440 fc537c61843ae0e8de8221fb493424ae 68 PRINTS PR00944 Copper ion binding protein signature 15 28 5.9E-10 T 06-07-2017 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 BWK49_RS16440 fc537c61843ae0e8de8221fb493424ae 68 PRINTS PR00944 Copper ion binding protein signature 28 41 5.9E-10 T 06-07-2017 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 BWK49_RS16440 fc537c61843ae0e8de8221fb493424ae 68 PRINTS PR00944 Copper ion binding protein signature 53 66 5.9E-10 T 06-07-2017 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 BWK49_RS16440 fc537c61843ae0e8de8221fb493424ae 68 PRINTS PR00944 Copper ion binding protein signature 3 15 5.9E-10 T 06-07-2017 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 BWK49_RS16440 fc537c61843ae0e8de8221fb493424ae 68 PRINTS PR00944 Copper ion binding protein signature 41 53 5.9E-10 T 06-07-2017 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 BWK49_RS16440 fc537c61843ae0e8de8221fb493424ae 68 SUPERFAMILY SSF55008 1 66 7.85E-19 T 06-07-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 BWK49_RS16440 fc537c61843ae0e8de8221fb493424ae 68 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 4 66 1.8E-18 T 06-07-2017 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 BWK49_RS16440 fc537c61843ae0e8de8221fb493424ae 68 ProSitePatterns PS01047 Heavy-metal-associated domain. 8 37 - T 06-07-2017 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 BWK49_RS16440 fc537c61843ae0e8de8221fb493424ae 68 Gene3D G3DSA:3.30.70.100 3 66 4.7E-23 T 06-07-2017 BWK49_RS10130 56625edf31bb12b9e80b205dc8fe083c 3677 SUPERFAMILY SSF47336 3591 3671 4.32E-14 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS10130 56625edf31bb12b9e80b205dc8fe083c 3677 SUPERFAMILY SSF52151 2312 2405 5.23E-68 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 BWK49_RS10130 56625edf31bb12b9e80b205dc8fe083c 3677 SUPERFAMILY SSF52151 2116 2250 5.23E-68 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 BWK49_RS10130 56625edf31bb12b9e80b205dc8fe083c 3677 SMART SM00825 Beta-ketoacyl synthase 14 440 1.9E-221 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain BWK49_RS10130 56625edf31bb12b9e80b205dc8fe083c 3677 SMART SM00825 Beta-ketoacyl synthase 1578 2003 1.6E-224 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain BWK49_RS10130 56625edf31bb12b9e80b205dc8fe083c 3677 Gene3D G3DSA:3.30.70.250 2249 2309 5.1E-4 T 06-07-2017 BWK49_RS10130 56625edf31bb12b9e80b205dc8fe083c 3677 Gene3D G3DSA:3.30.70.250 677 732 4.5E-5 T 06-07-2017 BWK49_RS10130 56625edf31bb12b9e80b205dc8fe083c 3677 Gene3D G3DSA:3.40.47.10 14 274 3.4E-100 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS10130 56625edf31bb12b9e80b205dc8fe083c 3677 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 550 849 1.5E-99 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain BWK49_RS10130 56625edf31bb12b9e80b205dc8fe083c 3677 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2119 2421 6.6E-104 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain BWK49_RS10130 56625edf31bb12b9e80b205dc8fe083c 3677 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 175 191 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site BWK49_RS10130 56625edf31bb12b9e80b205dc8fe083c 3677 SUPERFAMILY SSF51735 3098 3267 1.55E-34 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS10130 56625edf31bb12b9e80b205dc8fe083c 3677 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 15 262 5.2E-94 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal BWK49_RS10130 56625edf31bb12b9e80b205dc8fe083c 3677 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1576 1825 1.5E-95 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal BWK49_RS10130 56625edf31bb12b9e80b205dc8fe083c 3677 SUPERFAMILY SSF47336 1475 1590 1.83E-22 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS10130 56625edf31bb12b9e80b205dc8fe083c 3677 SUPERFAMILY SSF53901 1571 1940 8.35E-101 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS10130 56625edf31bb12b9e80b205dc8fe083c 3677 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1738 1754 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site BWK49_RS10130 56625edf31bb12b9e80b205dc8fe083c 3677 SUPERFAMILY SSF50129 2993 3134 1.07E-30 T 06-07-2017 IPR011032 GroES-like BWK49_RS10130 56625edf31bb12b9e80b205dc8fe083c 3677 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1506 1521 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site BWK49_RS10130 56625edf31bb12b9e80b205dc8fe083c 3677 Gene3D G3DSA:3.40.366.10 2311 2433 3.5E-75 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 BWK49_RS10130 56625edf31bb12b9e80b205dc8fe083c 3677 Gene3D G3DSA:3.40.366.10 2106 2245 3.5E-75 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 BWK49_RS10130 56625edf31bb12b9e80b205dc8fe083c 3677 Gene3D G3DSA:3.40.366.10 738 852 7.6E-73 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 BWK49_RS10130 56625edf31bb12b9e80b205dc8fe083c 3677 Gene3D G3DSA:3.40.366.10 540 672 7.6E-73 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 BWK49_RS10130 56625edf31bb12b9e80b205dc8fe083c 3677 SMART SM00829 3000 3305 1.0E-152 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 BWK49_RS10130 56625edf31bb12b9e80b205dc8fe083c 3677 SUPERFAMILY SSF55048 2249 2311 8.89E-8 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 BWK49_RS10130 56625edf31bb12b9e80b205dc8fe083c 3677 Gene3D G3DSA:1.10.1200.10 3593 3671 6.3E-13 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS10130 56625edf31bb12b9e80b205dc8fe083c 3677 Gene3D G3DSA:1.10.1200.10 1478 1581 1.7E-20 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS10130 56625edf31bb12b9e80b205dc8fe083c 3677 Gene3D G3DSA:3.90.180.10 2997 3130 4.4E-44 T 06-07-2017 IPR011032 GroES-like BWK49_RS10130 56625edf31bb12b9e80b205dc8fe083c 3677 Pfam PF08659 KR domain 3318 3495 1.4E-58 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS10130 56625edf31bb12b9e80b205dc8fe083c 3677 Pfam PF08659 KR domain 1192 1370 1.1E-59 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS10130 56625edf31bb12b9e80b205dc8fe083c 3677 SMART SM01294 1481 1547 1.0E-6 T 06-07-2017 BWK49_RS10130 56625edf31bb12b9e80b205dc8fe083c 3677 SMART SM00826 2483 2645 6.2E-40 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS10130 56625edf31bb12b9e80b205dc8fe083c 3677 Gene3D G3DSA:3.40.47.10 1582 1836 1.4E-98 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS10130 56625edf31bb12b9e80b205dc8fe083c 3677 SMART SM00823 Phosphopantetheine attachment site 3593 3665 1.2E-18 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS10130 56625edf31bb12b9e80b205dc8fe083c 3677 SMART SM00823 Phosphopantetheine attachment site 1480 1551 1.2E-22 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS10130 56625edf31bb12b9e80b205dc8fe083c 3677 SUPERFAMILY SSF51735 2778 2978 1.57E-27 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS10130 56625edf31bb12b9e80b205dc8fe083c 3677 Gene3D G3DSA:3.40.50.720 3131 3223 2.2E-26 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS10130 56625edf31bb12b9e80b205dc8fe083c 3677 Gene3D G3DSA:3.40.47.10 275 441 2.8E-63 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS10130 56625edf31bb12b9e80b205dc8fe083c 3677 Gene3D G3DSA:3.40.47.10 1839 2003 5.2E-63 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS10130 56625edf31bb12b9e80b205dc8fe083c 3677 SUPERFAMILY SSF51735 963 1178 9.84E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS10130 56625edf31bb12b9e80b205dc8fe083c 3677 Pfam PF13602 Zinc-binding dehydrogenase 3167 3305 4.5E-23 T 06-07-2017 BWK49_RS10130 56625edf31bb12b9e80b205dc8fe083c 3677 Gene3D G3DSA:3.40.50.720 3317 3526 4.6E-40 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS10130 56625edf31bb12b9e80b205dc8fe083c 3677 Gene3D G3DSA:3.40.50.720 1192 1404 1.2E-41 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS10130 56625edf31bb12b9e80b205dc8fe083c 3677 Pfam PF00550 Phosphopantetheine attachment site 3596 3661 6.8E-10 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS10130 56625edf31bb12b9e80b205dc8fe083c 3677 Pfam PF00550 Phosphopantetheine attachment site 1481 1547 1.3E-16 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS10130 56625edf31bb12b9e80b205dc8fe083c 3677 SUPERFAMILY SSF52151 740 833 3.66E-66 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 BWK49_RS10130 56625edf31bb12b9e80b205dc8fe083c 3677 SUPERFAMILY SSF52151 546 678 3.66E-66 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 BWK49_RS10130 56625edf31bb12b9e80b205dc8fe083c 3677 SUPERFAMILY SSF51735 1189 1431 1.76E-44 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS10130 56625edf31bb12b9e80b205dc8fe083c 3677 Pfam PF00698 Acyl transferase domain 549 858 5.4E-51 T 06-07-2017 IPR014043 Acyl transferase BWK49_RS10130 56625edf31bb12b9e80b205dc8fe083c 3677 Pfam PF00698 Acyl transferase domain 2118 2423 2.7E-56 T 06-07-2017 IPR014043 Acyl transferase BWK49_RS10130 56625edf31bb12b9e80b205dc8fe083c 3677 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 271 387 4.4E-42 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal BWK49_RS10130 56625edf31bb12b9e80b205dc8fe083c 3677 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1834 1950 1.1E-40 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal BWK49_RS10130 56625edf31bb12b9e80b205dc8fe083c 3677 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 390 510 7.0E-20 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS10130 56625edf31bb12b9e80b205dc8fe083c 3677 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1953 2081 1.4E-19 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS10130 56625edf31bb12b9e80b205dc8fe083c 3677 SUPERFAMILY SSF51735 3313 3568 1.54E-45 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS10130 56625edf31bb12b9e80b205dc8fe083c 3677 Pfam PF14765 Polyketide synthase dehydratase 2495 2770 4.7E-49 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS10130 56625edf31bb12b9e80b205dc8fe083c 3677 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1192 1372 1.5E-45 T 06-07-2017 BWK49_RS10130 56625edf31bb12b9e80b205dc8fe083c 3677 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3317 3497 1.1E-49 T 06-07-2017 BWK49_RS10130 56625edf31bb12b9e80b205dc8fe083c 3677 SUPERFAMILY SSF55048 677 739 4.97E-7 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 BWK49_RS10130 56625edf31bb12b9e80b205dc8fe083c 3677 SUPERFAMILY SSF53901 14 131 8.8E-100 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS10130 56625edf31bb12b9e80b205dc8fe083c 3677 SUPERFAMILY SSF53901 158 376 8.8E-100 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS16695 0acad37f7a2b147f0e4322db08eb74c3 214 Gene3D G3DSA:3.10.300.10 20 206 6.7E-53 T 06-07-2017 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 BWK49_RS16695 0acad37f7a2b147f0e4322db08eb74c3 214 Hamap MF_00527 Putative 3-methyladenine DNA glycosylase. 7 199 28.912 T 06-07-2017 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 BWK49_RS16695 0acad37f7a2b147f0e4322db08eb74c3 214 Pfam PF02245 Methylpurine-DNA glycosylase (MPG) 20 196 5.1E-55 T 06-07-2017 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 BWK49_RS16695 0acad37f7a2b147f0e4322db08eb74c3 214 SUPERFAMILY SSF50486 17 206 1.57E-55 T 06-07-2017 IPR011034 Formyl transferase, C-terminal-like GO:0003824 BWK49_RS16695 0acad37f7a2b147f0e4322db08eb74c3 214 TIGRFAM TIGR00567 3mg: DNA-3-methyladenine glycosylase 17 199 1.3E-60 T 06-07-2017 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 BWK49_RS18720 cd9c9f312f0d7990b3874133bc0ea830 174 SMART SM00530 4 59 6.3E-16 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 BWK49_RS18720 cd9c9f312f0d7990b3874133bc0ea830 174 SUPERFAMILY SSF47413 3 63 4.35E-17 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 BWK49_RS18720 cd9c9f312f0d7990b3874133bc0ea830 174 SUPERFAMILY SSF51182 52 170 1.34E-23 T 06-07-2017 IPR011051 RmlC-like cupin domain BWK49_RS18720 cd9c9f312f0d7990b3874133bc0ea830 174 Gene3D G3DSA:1.10.260.40 5 88 4.8E-24 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 BWK49_RS18720 cd9c9f312f0d7990b3874133bc0ea830 174 Gene3D G3DSA:2.60.120.10 89 169 2.7E-18 T 06-07-2017 IPR014710 RmlC-like jelly roll fold BWK49_RS18720 cd9c9f312f0d7990b3874133bc0ea830 174 Pfam PF07883 Cupin domain 108 166 7.6E-15 T 06-07-2017 IPR013096 Cupin 2, conserved barrel BWK49_RS18720 cd9c9f312f0d7990b3874133bc0ea830 174 Pfam PF01381 Helix-turn-helix 5 57 4.0E-16 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 BWK49_RS16905 4ed62ce5958f598ff0f63a8cd4b57204 479 Gene3D G3DSA:3.40.50.1390 16 145 2.6E-21 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 BWK49_RS16905 4ed62ce5958f598ff0f63a8cd4b57204 479 Pfam PF13408 Recombinase zinc beta ribbon domain 283 342 3.7E-9 T 06-07-2017 IPR025827 Recombinase zinc beta ribbon domain BWK49_RS16905 4ed62ce5958f598ff0f63a8cd4b57204 479 SMART SM00857 16 165 5.4E-40 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 BWK49_RS16905 4ed62ce5958f598ff0f63a8cd4b57204 479 Pfam PF00239 Resolvase, N terminal domain 16 163 6.7E-27 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 BWK49_RS16905 4ed62ce5958f598ff0f63a8cd4b57204 479 Pfam PF07508 Recombinase 183 262 4.6E-10 T 06-07-2017 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 BWK49_RS16905 4ed62ce5958f598ff0f63a8cd4b57204 479 SUPERFAMILY SSF53041 16 164 4.97E-26 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 BWK49_RS15395 c45194cfa0dd492cb64631644dbcfeae 511 Gene3D G3DSA:3.30.300.30 402 505 7.0E-25 T 06-07-2017 BWK49_RS15395 c45194cfa0dd492cb64631644dbcfeae 511 Pfam PF00501 AMP-binding enzyme 6 405 5.7E-74 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS15395 c45194cfa0dd492cb64631644dbcfeae 511 Gene3D G3DSA:2.30.38.10 326 396 1.2E-13 T 06-07-2017 BWK49_RS15395 c45194cfa0dd492cb64631644dbcfeae 511 SUPERFAMILY SSF56801 4 505 1.83E-128 T 06-07-2017 BWK49_RS15395 c45194cfa0dd492cb64631644dbcfeae 511 ProSitePatterns PS00455 Putative AMP-binding domain signature. 154 165 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS15395 c45194cfa0dd492cb64631644dbcfeae 511 Gene3D G3DSA:3.40.50.980 3 160 1.4E-30 T 06-07-2017 BWK49_RS15395 c45194cfa0dd492cb64631644dbcfeae 511 Gene3D G3DSA:3.40.50.980 161 325 9.2E-39 T 06-07-2017 BWK49_RS15395 c45194cfa0dd492cb64631644dbcfeae 511 Pfam PF13193 AMP-binding enzyme C-terminal domain 414 492 6.7E-16 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS15010 cd58a648a3198bce6e4b6a4fd71a9bbb 478 SMART SM01240 11 474 4.2E-179 T 06-07-2017 BWK49_RS15010 cd58a648a3198bce6e4b6a4fd71a9bbb 478 Pfam PF00571 CBS domain 98 138 2.7E-5 T 06-07-2017 IPR000644 CBS domain BWK49_RS15010 cd58a648a3198bce6e4b6a4fd71a9bbb 478 Gene3D G3DSA:3.20.20.70 10 475 9.4E-128 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 BWK49_RS15010 cd58a648a3198bce6e4b6a4fd71a9bbb 478 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 13 473 1.4E-99 T 06-07-2017 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 BWK49_RS15010 cd58a648a3198bce6e4b6a4fd71a9bbb 478 SUPERFAMILY SSF51412 202 473 1.2E-90 T 06-07-2017 BWK49_RS15010 cd58a648a3198bce6e4b6a4fd71a9bbb 478 SUPERFAMILY SSF51412 10 93 1.2E-90 T 06-07-2017 BWK49_RS15010 cd58a648a3198bce6e4b6a4fd71a9bbb 478 PIRSF PIRSF000130 2 478 4.5E-142 T 06-07-2017 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-73817 BWK49_RS15010 cd58a648a3198bce6e4b6a4fd71a9bbb 478 TIGRFAM TIGR01303 IMP_DH_rel_1: IMP dehydrogenase family protein 2 475 4.8E-264 T 06-07-2017 IPR005991 IMP dehydrogenase-related 1 BWK49_RS15010 cd58a648a3198bce6e4b6a4fd71a9bbb 478 SUPERFAMILY SSF54631 93 202 1.52E-16 T 06-07-2017 BWK49_RS12870 b1a43398a662aaaaaa7c7bd212e8efd9 364 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 257 311 - T 06-07-2017 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 BWK49_RS12870 b1a43398a662aaaaaa7c7bd212e8efd9 364 SUPERFAMILY SSF81464 44 147 1.52E-15 T 06-07-2017 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 BWK49_RS12870 b1a43398a662aaaaaa7c7bd212e8efd9 364 SUPERFAMILY SSF49503 234 345 2.79E-36 T 06-07-2017 IPR008972 Cupredoxin BWK49_RS12870 b1a43398a662aaaaaa7c7bd212e8efd9 364 SUPERFAMILY SSF49503 152 175 2.79E-36 T 06-07-2017 IPR008972 Cupredoxin BWK49_RS12870 b1a43398a662aaaaaa7c7bd212e8efd9 364 Gene3D G3DSA:2.60.40.420 154 330 3.1E-39 T 06-07-2017 IPR008972 Cupredoxin BWK49_RS12870 b1a43398a662aaaaaa7c7bd212e8efd9 364 Gene3D G3DSA:1.10.287.90 58 148 1.3E-13 T 06-07-2017 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 BWK49_RS12870 b1a43398a662aaaaaa7c7bd212e8efd9 364 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 239 317 6.7E-12 T 06-07-2017 IPR002429 Cytochrome c oxidase subunit II C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 BWK49_RS21545 95c26cac9b120271520dfac2f7c1f3b7 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 8.7E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS21545 95c26cac9b120271520dfac2f7c1f3b7 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 8.7E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS21545 95c26cac9b120271520dfac2f7c1f3b7 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 8.7E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS21545 95c26cac9b120271520dfac2f7c1f3b7 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 8.7E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS21545 95c26cac9b120271520dfac2f7c1f3b7 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 8.7E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS21545 95c26cac9b120271520dfac2f7c1f3b7 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 8.7E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS21545 95c26cac9b120271520dfac2f7c1f3b7 247 Gene3D G3DSA:3.40.50.720 3 246 5.4E-81 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS21545 95c26cac9b120271520dfac2f7c1f3b7 247 SUPERFAMILY SSF51735 3 246 2.71E-78 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS21545 95c26cac9b120271520dfac2f7c1f3b7 247 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 9 244 7.6E-62 T 06-07-2017 BWK49_RS21545 95c26cac9b120271520dfac2f7c1f3b7 247 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 182 1.9E-5 T 06-07-2017 BWK49_RS21545 95c26cac9b120271520dfac2f7c1f3b7 247 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 138 166 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS21545 95c26cac9b120271520dfac2f7c1f3b7 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 170 1.1E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS21545 95c26cac9b120271520dfac2f7c1f3b7 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 1.1E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS21545 95c26cac9b120271520dfac2f7c1f3b7 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 1.1E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS26595 de018fdfa4ff627cdafac63babdad2fe 334 Gene3D G3DSA:3.40.50.1980 45 168 1.6E-21 T 06-07-2017 BWK49_RS26595 de018fdfa4ff627cdafac63babdad2fe 334 Gene3D G3DSA:3.40.50.1980 169 331 4.7E-10 T 06-07-2017 BWK49_RS26595 de018fdfa4ff627cdafac63babdad2fe 334 SUPERFAMILY SSF53807 46 327 7.46E-38 T 06-07-2017 BWK49_RS26595 de018fdfa4ff627cdafac63babdad2fe 334 Pfam PF01497 Periplasmic binding protein 79 302 1.4E-42 T 06-07-2017 IPR002491 ABC transporter periplasmic binding domain GO:0005488 BWK49_RS26595 de018fdfa4ff627cdafac63babdad2fe 334 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 5 27 7.7E-4 T 06-07-2017 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal BWK49_RS07555 59a8d919a12f2efa7625b5892983247e 719 Pfam PF00702 haloacid dehalogenase-like hydrolase 329 566 3.6E-33 T 06-07-2017 BWK49_RS07555 59a8d919a12f2efa7625b5892983247e 719 Pfam PF00122 E1-E2 ATPase 84 324 1.5E-39 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 BWK49_RS07555 59a8d919a12f2efa7625b5892983247e 719 Gene3D G3DSA:2.70.150.10 53 222 7.5E-23 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 BWK49_RS07555 59a8d919a12f2efa7625b5892983247e 719 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 335 341 - T 06-07-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 BWK49_RS07555 59a8d919a12f2efa7625b5892983247e 719 Hamap MF_00285 Potassium-transporting ATPase ATP-binding subunit [kdpB]. 27 716 39.817 T 06-07-2017 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 BWK49_RS07555 59a8d919a12f2efa7625b5892983247e 719 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 472 635 1.7E-39 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 BWK49_RS07555 59a8d919a12f2efa7625b5892983247e 719 SUPERFAMILY SSF56784 395 436 7.42E-37 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS07555 59a8d919a12f2efa7625b5892983247e 719 SUPERFAMILY SSF56784 321 345 7.42E-37 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS07555 59a8d919a12f2efa7625b5892983247e 719 SUPERFAMILY SSF56784 471 595 7.42E-37 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS07555 59a8d919a12f2efa7625b5892983247e 719 Gene3D G3DSA:3.40.50.1000 481 599 2.8E-36 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS07555 59a8d919a12f2efa7625b5892983247e 719 TIGRFAM TIGR01497 kdpB: K+-transporting ATPase, B subunit 24 712 1.8E-298 T 06-07-2017 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 BWK49_RS07555 59a8d919a12f2efa7625b5892983247e 719 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 168 182 3.4E-25 T 06-07-2017 BWK49_RS07555 59a8d919a12f2efa7625b5892983247e 719 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 575 587 3.4E-25 T 06-07-2017 BWK49_RS07555 59a8d919a12f2efa7625b5892983247e 719 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 333 347 3.4E-25 T 06-07-2017 BWK49_RS07555 59a8d919a12f2efa7625b5892983247e 719 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 552 571 3.4E-25 T 06-07-2017 BWK49_RS07555 59a8d919a12f2efa7625b5892983247e 719 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 499 509 3.4E-25 T 06-07-2017 BWK49_RS07555 59a8d919a12f2efa7625b5892983247e 719 SUPERFAMILY SSF81653 133 221 2.22E-19 T 06-07-2017 BWK49_RS07555 59a8d919a12f2efa7625b5892983247e 719 SUPERFAMILY SSF81665 50 115 2.75E-11 T 06-07-2017 BWK49_RS07555 59a8d919a12f2efa7625b5892983247e 719 SUPERFAMILY SSF81665 222 327 2.75E-11 T 06-07-2017 BWK49_RS07555 59a8d919a12f2efa7625b5892983247e 719 Gene3D G3DSA:3.40.1110.10 344 480 6.0E-45 T 06-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 BWK49_RS02135 148a97ab28d9dd933d993876e9efb107 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 143 151 1.9E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS02135 148a97ab28d9dd933d993876e9efb107 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 163 182 1.9E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS02135 148a97ab28d9dd933d993876e9efb107 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 89 100 1.9E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS02135 148a97ab28d9dd933d993876e9efb107 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 137 153 8.6E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS02135 148a97ab28d9dd933d993876e9efb107 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 89 100 8.6E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS02135 148a97ab28d9dd933d993876e9efb107 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 8.6E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS02135 148a97ab28d9dd933d993876e9efb107 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 183 200 8.6E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS02135 148a97ab28d9dd933d993876e9efb107 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 182 8.6E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS02135 148a97ab28d9dd933d993876e9efb107 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 8.6E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS02135 148a97ab28d9dd933d993876e9efb107 254 SUPERFAMILY SSF51735 12 253 3.19E-72 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS02135 148a97ab28d9dd933d993876e9efb107 254 Gene3D G3DSA:3.40.50.720 7 252 3.3E-73 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS02135 148a97ab28d9dd933d993876e9efb107 254 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 21 253 8.3E-52 T 06-07-2017 BWK49_RS05015 6621a402f2da7b68b5f8bd86e4514f9b 267 PIRSF PIRSF003073 16 267 1.4E-91 T 06-07-2017 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein BWK49_RS05015 6621a402f2da7b68b5f8bd86e4514f9b 267 SMART SM00382 114 246 1.2E-5 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS05015 6621a402f2da7b68b5f8bd86e4514f9b 267 Pfam PF01695 IstB-like ATP binding protein 73 246 1.2E-51 T 06-07-2017 IPR002611 IstB-like ATP-binding protein GO:0005524 BWK49_RS05015 6621a402f2da7b68b5f8bd86e4514f9b 267 Gene3D G3DSA:3.40.50.300 91 246 7.3E-22 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS05015 6621a402f2da7b68b5f8bd86e4514f9b 267 SUPERFAMILY SSF52540 98 248 2.78E-25 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS16470 f3da900557c5bd3d4ad528ba07721c54 365 Gene3D G3DSA:3.40.50.1100 144 302 3.8E-37 T 06-07-2017 BWK49_RS16470 f3da900557c5bd3d4ad528ba07721c54 365 Gene3D G3DSA:3.40.50.1100 1 32 3.8E-37 T 06-07-2017 BWK49_RS16470 f3da900557c5bd3d4ad528ba07721c54 365 Gene3D G3DSA:3.40.50.1100 33 138 5.0E-26 T 06-07-2017 BWK49_RS16470 f3da900557c5bd3d4ad528ba07721c54 365 SUPERFAMILY SSF53686 1 304 1.96E-69 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme BWK49_RS16470 f3da900557c5bd3d4ad528ba07721c54 365 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 23 41 - T 06-07-2017 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 BWK49_RS16470 f3da900557c5bd3d4ad528ba07721c54 365 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 1 283 5.6E-52 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme BWK49_RS23990 707ff5db0d3ac12b33498cae54c75a05 283 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 8 264 31.249 T 06-07-2017 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 BWK49_RS23990 707ff5db0d3ac12b33498cae54c75a05 283 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 10 259 1.5E-48 T 06-07-2017 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 BWK49_RS23990 707ff5db0d3ac12b33498cae54c75a05 283 Pfam PF01416 tRNA pseudouridine synthase 164 265 1.7E-24 T 06-07-2017 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 BWK49_RS23990 707ff5db0d3ac12b33498cae54c75a05 283 Gene3D G3DSA:3.30.70.660 127 262 1.7E-40 T 06-07-2017 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 BWK49_RS23990 707ff5db0d3ac12b33498cae54c75a05 283 SUPERFAMILY SSF55120 8 274 6.19E-75 T 06-07-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 BWK49_RS23990 707ff5db0d3ac12b33498cae54c75a05 283 Gene3D G3DSA:3.30.70.580 8 125 8.9E-32 T 06-07-2017 IPR020094 Pseudouridine synthase I, TruA, N-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 BWK49_RS23990 707ff5db0d3ac12b33498cae54c75a05 283 PIRSF PIRSF001430 7 281 5.0E-72 T 06-07-2017 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 BWK49_RS03275 2f064391355898fd9244bdf7b51512d4 290 Pfam PF12697 Alpha/beta hydrolase family 39 280 8.7E-21 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS03275 2f064391355898fd9244bdf7b51512d4 290 PRINTS PR00111 Alpha/beta hydrolase fold signature 233 247 8.3E-22 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS03275 2f064391355898fd9244bdf7b51512d4 290 PRINTS PR00111 Alpha/beta hydrolase fold signature 110 123 8.3E-22 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS03275 2f064391355898fd9244bdf7b51512d4 290 PRINTS PR00111 Alpha/beta hydrolase fold signature 65 80 8.3E-22 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS03275 2f064391355898fd9244bdf7b51512d4 290 PRINTS PR00111 Alpha/beta hydrolase fold signature 124 137 8.3E-22 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS03275 2f064391355898fd9244bdf7b51512d4 290 SUPERFAMILY SSF53474 12 288 3.62E-63 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS03275 2f064391355898fd9244bdf7b51512d4 290 Gene3D G3DSA:3.40.50.1820 11 287 6.2E-65 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS15040 2bec5de30ee97cdc7f6f8bc4955f6889 346 SUPERFAMILY SSF54631 208 344 8.46E-18 T 06-07-2017 BWK49_RS15040 2bec5de30ee97cdc7f6f8bc4955f6889 346 Pfam PF01595 Domain of unknown function DUF21 8 202 1.6E-37 T 06-07-2017 IPR002550 Domain of unknown function DUF21 BWK49_RS15040 2bec5de30ee97cdc7f6f8bc4955f6889 346 Gene3D G3DSA:3.10.580.10 233 338 4.7E-11 T 06-07-2017 BWK49_RS23950 1f57e035c1eac2533a6a3ad211d21f5c 105 Pfam PF06013 Proteins of 100 residues with WXG 7 91 7.3E-16 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like BWK49_RS23950 1f57e035c1eac2533a6a3ad211d21f5c 105 Gene3D G3DSA:1.10.287.1060 7 95 1.9E-25 T 06-07-2017 BWK49_RS23950 1f57e035c1eac2533a6a3ad211d21f5c 105 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 8 94 1.2E-12 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like BWK49_RS23950 1f57e035c1eac2533a6a3ad211d21f5c 105 SUPERFAMILY SSF140453 6 98 3.01E-19 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like BWK49_RS14510 04ed8a4177d9ee06ee749ab10154fe11 212 SUPERFAMILY SSF46785 1 92 1.89E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS14510 04ed8a4177d9ee06ee749ab10154fe11 212 SUPERFAMILY SSF55718 100 203 6.92E-14 T 06-07-2017 IPR003033 SCP2 sterol-binding domain BWK49_RS14510 04ed8a4177d9ee06ee749ab10154fe11 212 Pfam PF02036 SCP-2 sterol transfer family 116 200 2.5E-8 T 06-07-2017 IPR003033 SCP2 sterol-binding domain BWK49_RS14510 04ed8a4177d9ee06ee749ab10154fe11 212 Pfam PF01638 HxlR-like helix-turn-helix 7 91 3.3E-19 T 06-07-2017 IPR002577 Helix-turn-helix, HxlR type BWK49_RS14510 04ed8a4177d9ee06ee749ab10154fe11 212 Gene3D G3DSA:1.10.10.10 1 92 2.9E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS13715 95c41cc61938f3763ba9b9008a298ade 505 Pfam PF00135 Carboxylesterase family 9 490 8.9E-100 T 06-07-2017 IPR002018 Carboxylesterase, type B BWK49_RS13715 95c41cc61938f3763ba9b9008a298ade 505 SUPERFAMILY SSF53474 6 501 6.91E-117 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS13715 95c41cc61938f3763ba9b9008a298ade 505 Gene3D G3DSA:3.40.50.1820 5 500 6.1E-132 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS13715 95c41cc61938f3763ba9b9008a298ade 505 ProSitePatterns PS00941 Carboxylesterases type-B signature 2. 86 96 - T 06-07-2017 IPR019819 Carboxylesterase type B, conserved site BWK49_RS13715 95c41cc61938f3763ba9b9008a298ade 505 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 185 200 - T 06-07-2017 IPR019826 Carboxylesterase type B, active site BWK49_RS13715 95c41cc61938f3763ba9b9008a298ade 505 ProSitePatterns PS01173 Lipolytic enzymes "G-D-X-G" family, putative histidine active site. 107 122 - T 06-07-2017 IPR002168 Lipase, GDXG, putative histidine active site GO:0008152|GO:0016787 Reactome: R-HSA-163560 BWK49_RS08465 fc0b41bf443561449f057290c1e07e55 282 SUPERFAMILY SSF51717 4 273 1.57E-76 T 06-07-2017 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 BWK49_RS08465 fc0b41bf443561449f057290c1e07e55 282 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 8 23 - T 06-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 BWK49_RS08465 fc0b41bf443561449f057290c1e07e55 282 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 42 55 - T 06-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 BWK49_RS08465 fc0b41bf443561449f057290c1e07e55 282 Pfam PF00809 Pterin binding enzyme 9 253 7.5E-68 T 06-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 BWK49_RS08465 fc0b41bf443561449f057290c1e07e55 282 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 8 267 7.0E-86 T 06-07-2017 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 BWK49_RS08465 fc0b41bf443561449f057290c1e07e55 282 Gene3D G3DSA:3.20.20.20 4 272 1.4E-81 T 06-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 BWK49_RS13205 b10f4db570a8f3008ad2c5c47c85b407 885 SUPERFAMILY SSF46894 792 858 1.05E-17 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 BWK49_RS13205 b10f4db570a8f3008ad2c5c47c85b407 885 Gene3D G3DSA:3.40.50.300 16 105 2.1E-7 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS13205 b10f4db570a8f3008ad2c5c47c85b407 885 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 816 832 7.5E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS13205 b10f4db570a8f3008ad2c5c47c85b407 885 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 832 844 7.5E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS13205 b10f4db570a8f3008ad2c5c47c85b407 885 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 802 816 7.5E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS13205 b10f4db570a8f3008ad2c5c47c85b407 885 SMART SM00382 12 177 1.9E-7 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS13205 b10f4db570a8f3008ad2c5c47c85b407 885 Gene3D G3DSA:1.10.10.10 802 858 7.3E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS13205 b10f4db570a8f3008ad2c5c47c85b407 885 Pfam PF13401 AAA domain 17 112 2.7E-7 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS13205 b10f4db570a8f3008ad2c5c47c85b407 885 SUPERFAMILY SSF52540 5 195 3.15E-12 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS13205 b10f4db570a8f3008ad2c5c47c85b407 885 Pfam PF00196 Bacterial regulatory proteins, luxR family 802 855 1.1E-14 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS13205 b10f4db570a8f3008ad2c5c47c85b407 885 SMART SM00421 799 856 8.5E-19 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS13205 b10f4db570a8f3008ad2c5c47c85b407 885 ProSitePatterns PS00622 LuxR-type HTH domain signature. 816 843 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS04700 f92c65e33b261eb5ebe174e524596d2d 150 SUPERFAMILY SSF54637 11 143 2.56E-21 T 06-07-2017 IPR029069 HotDog domain BWK49_RS04700 f92c65e33b261eb5ebe174e524596d2d 150 Gene3D G3DSA:3.10.129.10 10 135 9.2E-20 T 06-07-2017 IPR029069 HotDog domain BWK49_RS04700 f92c65e33b261eb5ebe174e524596d2d 150 Pfam PF01575 MaoC like domain 26 124 2.9E-7 T 06-07-2017 IPR002539 MaoC-like domain BWK49_RS21355 94a3f6bc9998efaf678e673e242cc12b 204 Gene3D G3DSA:1.10.357.10 22 183 3.6E-28 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS21355 94a3f6bc9998efaf678e673e242cc12b 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 32 74 1.7E-16 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS21355 94a3f6bc9998efaf678e673e242cc12b 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 45 6.0E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS21355 94a3f6bc9998efaf678e673e242cc12b 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 53 76 6.0E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS21355 94a3f6bc9998efaf678e673e242cc12b 204 SUPERFAMILY SSF46689 23 83 9.93E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS01265 904ec6f55ef95b988d83dbcf664c7bb8 276 Pfam PF01061 ABC-2 type transporter 29 237 1.0E-25 T 06-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 BWK49_RS17880 908863ac2cf2c0b0ccb3f8dac030a272 335 Pfam PF13519 von Willebrand factor type A domain 99 212 6.3E-21 T 06-07-2017 IPR002035 von Willebrand factor, type A BWK49_RS17880 908863ac2cf2c0b0ccb3f8dac030a272 335 Hamap MF_01340 UPF0353 protein . 9 335 56.175 T 06-07-2017 IPR022933 Uncharacterised protein family UPF0353 BWK49_RS17880 908863ac2cf2c0b0ccb3f8dac030a272 335 SUPERFAMILY SSF53300 94 297 7.37E-31 T 06-07-2017 IPR002035 von Willebrand factor, type A BWK49_RS17880 908863ac2cf2c0b0ccb3f8dac030a272 335 SMART SM00327 96 274 3.9E-28 T 06-07-2017 IPR002035 von Willebrand factor, type A BWK49_RS17880 908863ac2cf2c0b0ccb3f8dac030a272 335 Gene3D G3DSA:3.40.50.410 97 298 6.0E-25 T 06-07-2017 IPR002035 von Willebrand factor, type A BWK49_RS01440 df357d2e6e1265f171ebf7256b25ae70 443 SUPERFAMILY SSF58104 185 271 8.11E-5 T 06-07-2017 BWK49_RS01440 df357d2e6e1265f171ebf7256b25ae70 443 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 10 298 2.4E-74 T 06-07-2017 IPR005693 Virulence factor Mce protein BWK49_RS01440 df357d2e6e1265f171ebf7256b25ae70 443 Pfam PF02470 MlaD protein 36 109 2.7E-13 T 06-07-2017 IPR003399 Mce/MlaD BWK49_RS15290 e17132d8596c89a2431d2d1ea3256c09 64 Gene3D G3DSA:3.30.70.20 2 63 5.0E-10 T 06-07-2017 BWK49_RS15290 e17132d8596c89a2431d2d1ea3256c09 64 Pfam PF13459 4Fe-4S single cluster domain 3 60 5.6E-12 T 06-07-2017 BWK49_RS15290 e17132d8596c89a2431d2d1ea3256c09 64 SUPERFAMILY SSF54862 2 61 1.09E-7 T 06-07-2017 BWK49_RS21315 f2ffd86d075695aabbf8785038b20c66 152 Gene3D G3DSA:3.40.50.620 2 150 8.1E-32 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold BWK49_RS21315 f2ffd86d075695aabbf8785038b20c66 152 Pfam PF00582 Universal stress protein family 4 149 3.8E-26 T 06-07-2017 IPR006016 UspA GO:0006950 BWK49_RS21315 f2ffd86d075695aabbf8785038b20c66 152 PRINTS PR01438 Universal stress protein signature 127 149 2.6E-15 T 06-07-2017 IPR006015 Universal stress protein A BWK49_RS21315 f2ffd86d075695aabbf8785038b20c66 152 PRINTS PR01438 Universal stress protein signature 4 22 2.6E-15 T 06-07-2017 IPR006015 Universal stress protein A BWK49_RS21315 f2ffd86d075695aabbf8785038b20c66 152 PRINTS PR01438 Universal stress protein signature 109 121 2.6E-15 T 06-07-2017 IPR006015 Universal stress protein A BWK49_RS21315 f2ffd86d075695aabbf8785038b20c66 152 SUPERFAMILY SSF52402 2 149 2.01E-27 T 06-07-2017 BWK49_RS27030 717443b373a48f92e47f47ce83040cde 509 Gene3D G3DSA:3.40.50.980 9 167 6.5E-31 T 06-07-2017 BWK49_RS27030 717443b373a48f92e47f47ce83040cde 509 Pfam PF00501 AMP-binding enzyme 9 410 1.6E-71 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS27030 717443b373a48f92e47f47ce83040cde 509 Pfam PF13193 AMP-binding enzyme C-terminal domain 419 497 4.1E-17 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS27030 717443b373a48f92e47f47ce83040cde 509 Gene3D G3DSA:3.30.300.30 406 505 7.5E-26 T 06-07-2017 BWK49_RS27030 717443b373a48f92e47f47ce83040cde 509 Gene3D G3DSA:3.40.50.980 168 331 7.1E-37 T 06-07-2017 BWK49_RS27030 717443b373a48f92e47f47ce83040cde 509 SUPERFAMILY SSF56801 9 507 3.27E-122 T 06-07-2017 BWK49_RS27030 717443b373a48f92e47f47ce83040cde 509 Gene3D G3DSA:2.30.38.10 332 401 3.8E-17 T 06-07-2017 BWK49_RS27030 717443b373a48f92e47f47ce83040cde 509 ProSitePatterns PS00455 Putative AMP-binding domain signature. 161 172 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS05925 e36e87b7f2d9e33f000d68b994c16238 275 SUPERFAMILY SSF51735 12 258 1.55E-45 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS05925 e36e87b7f2d9e33f000d68b994c16238 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 184 8.4E-27 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05925 e36e87b7f2d9e33f000d68b994c16238 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 8.4E-27 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05925 e36e87b7f2d9e33f000d68b994c16238 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 221 241 8.4E-27 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05925 e36e87b7f2d9e33f000d68b994c16238 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 8.4E-27 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05925 e36e87b7f2d9e33f000d68b994c16238 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 112 128 8.4E-27 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05925 e36e87b7f2d9e33f000d68b994c16238 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 186 203 8.4E-27 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05925 e36e87b7f2d9e33f000d68b994c16238 275 Gene3D G3DSA:3.40.50.720 12 257 4.6E-48 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS05925 e36e87b7f2d9e33f000d68b994c16238 275 Pfam PF00106 short chain dehydrogenase 15 130 7.2E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05925 e36e87b7f2d9e33f000d68b994c16238 275 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 163 256 1.2E-16 T 06-07-2017 BWK49_RS28805 880bace9e776b4250d3a182e92681768 85 SUPERFAMILY SSF143011 4 84 1.31E-27 T 06-07-2017 BWK49_RS28805 880bace9e776b4250d3a182e92681768 85 TIGRFAM TIGR02116 toxin_Txe_YoeB: addiction module toxin, Txe/YoeB family 6 85 9.5E-37 T 06-07-2017 IPR009614 Toxin YoeB GO:0004519|GO:0006401 BWK49_RS28805 880bace9e776b4250d3a182e92681768 85 Pfam PF06769 YoeB-like toxin of bacterial type II toxin-antitoxin system 6 85 1.7E-39 T 06-07-2017 IPR009614 Toxin YoeB GO:0004519|GO:0006401 BWK49_RS02990 d4dfd11469e78d3d17512d5742b85a01 461 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 239 454 3.7E-74 T 06-07-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 BWK49_RS02990 d4dfd11469e78d3d17512d5742b85a01 461 TIGRFAM TIGR00666 PBP4: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase 232 439 1.2E-69 T 06-07-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 BWK49_RS02990 d4dfd11469e78d3d17512d5742b85a01 461 TIGRFAM TIGR00666 PBP4: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase 98 233 2.3E-41 T 06-07-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 BWK49_RS02990 d4dfd11469e78d3d17512d5742b85a01 461 Gene3D G3DSA:3.40.710.10 93 144 5.4E-58 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like BWK49_RS02990 d4dfd11469e78d3d17512d5742b85a01 461 Gene3D G3DSA:3.40.710.10 271 460 5.4E-58 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like BWK49_RS02990 d4dfd11469e78d3d17512d5742b85a01 461 SUPERFAMILY SSF56601 81 453 7.75E-57 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like BWK49_RS02990 d4dfd11469e78d3d17512d5742b85a01 461 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 111 130 5.1E-30 T 06-07-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 BWK49_RS02990 d4dfd11469e78d3d17512d5742b85a01 461 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 333 347 5.1E-30 T 06-07-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 BWK49_RS02990 d4dfd11469e78d3d17512d5742b85a01 461 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 348 362 5.1E-30 T 06-07-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 BWK49_RS02990 d4dfd11469e78d3d17512d5742b85a01 461 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 416 429 5.1E-30 T 06-07-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 BWK49_RS02990 d4dfd11469e78d3d17512d5742b85a01 461 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 276 298 5.1E-30 T 06-07-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 BWK49_RS06730 46a71310d052df3d1eec20598f1dcca9 282 SUPERFAMILY SSF52980 177 275 6.97E-6 T 06-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 BWK49_RS06730 46a71310d052df3d1eec20598f1dcca9 282 Pfam PF04480 Protein of unknown function (DUF559) 212 274 2.9E-5 T 06-07-2017 IPR007569 Domain of unknown function DUF559 BWK49_RS20850 38f078c50f83e46592903e4e3eb8c450 733 SUPERFAMILY SSF143724 151 361 3.14E-65 T 06-07-2017 BWK49_RS20850 38f078c50f83e46592903e4e3eb8c450 733 SUPERFAMILY SSF56024 375 549 2.95E-56 T 06-07-2017 BWK49_RS20850 38f078c50f83e46592903e4e3eb8c450 733 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 47 728 1.3E-244 T 06-07-2017 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 BWK49_RS20850 38f078c50f83e46592903e4e3eb8c450 733 SUPERFAMILY SSF140356 45 149 9.29E-36 T 06-07-2017 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 BWK49_RS20850 38f078c50f83e46592903e4e3eb8c450 733 PIRSF PIRSF015589 29 732 3.0E-271 T 06-07-2017 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 BWK49_RS20850 38f078c50f83e46592903e4e3eb8c450 733 Hamap MF_00347 Polyphosphate kinase [ppk]. 45 730 36.86 T 06-07-2017 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 BWK49_RS20850 38f078c50f83e46592903e4e3eb8c450 733 Gene3D G3DSA:3.30.870.10 365 552 2.3E-78 T 06-07-2017 BWK49_RS20850 38f078c50f83e46592903e4e3eb8c450 733 Pfam PF02503 Polyphosphate kinase middle domain 163 371 4.8E-68 T 06-07-2017 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 BWK49_RS20850 38f078c50f83e46592903e4e3eb8c450 733 Pfam PF13089 Polyphosphate kinase N-terminal domain 48 154 6.6E-36 T 06-07-2017 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 BWK49_RS20850 38f078c50f83e46592903e4e3eb8c450 733 Gene3D G3DSA:3.30.870.10 553 731 5.4E-68 T 06-07-2017 BWK49_RS20850 38f078c50f83e46592903e4e3eb8c450 733 Pfam PF13090 Polyphosphate kinase C-terminal domain 382 727 8.4E-149 T 06-07-2017 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 BWK49_RS20850 38f078c50f83e46592903e4e3eb8c450 733 SUPERFAMILY SSF56024 553 731 2.92E-63 T 06-07-2017 BWK49_RS20850 38f078c50f83e46592903e4e3eb8c450 733 Gene3D G3DSA:3.30.1840.10 150 350 4.3E-73 T 06-07-2017 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 BWK49_RS01800 5f64e441ae7b39d56c8158e1862707a2 336 SMART SM01130 10 314 1.7E-28 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 BWK49_RS01800 5f64e441ae7b39d56c8158e1862707a2 336 Pfam PF00701 Dihydrodipicolinate synthetase family 31 179 7.2E-22 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 BWK49_RS01800 5f64e441ae7b39d56c8158e1862707a2 336 PRINTS PR00146 Dihydrodipicolinate synthase signature 145 162 3.8E-6 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 BWK49_RS01800 5f64e441ae7b39d56c8158e1862707a2 336 PRINTS PR00146 Dihydrodipicolinate synthase signature 51 72 3.8E-6 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 BWK49_RS01800 5f64e441ae7b39d56c8158e1862707a2 336 PRINTS PR00146 Dihydrodipicolinate synthase signature 87 105 3.8E-6 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 BWK49_RS01800 5f64e441ae7b39d56c8158e1862707a2 336 Gene3D G3DSA:3.20.20.70 5 324 1.1E-53 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 BWK49_RS01800 5f64e441ae7b39d56c8158e1862707a2 336 SUPERFAMILY SSF51569 11 313 1.15E-49 T 06-07-2017 BWK49_RS01800 5f64e441ae7b39d56c8158e1862707a2 336 PIRSF PIRSF001365 12 321 4.0E-49 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 BWK49_RS13910 b3921720495e866e2584b7b0d25c90e9 202 ProSitePatterns PS01081 TetR-type HTH domain signature. 31 62 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site BWK49_RS13910 b3921720495e866e2584b7b0d25c90e9 202 Gene3D G3DSA:1.10.357.10 58 196 9.3E-22 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS13910 b3921720495e866e2584b7b0d25c90e9 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 60 2.5E-14 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS13910 b3921720495e866e2584b7b0d25c90e9 202 Gene3D G3DSA:1.10.10.60 7 57 4.1E-19 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS13910 b3921720495e866e2584b7b0d25c90e9 202 SUPERFAMILY SSF46689 7 64 8.98E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS13910 b3921720495e866e2584b7b0d25c90e9 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 2.0E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS13910 b3921720495e866e2584b7b0d25c90e9 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 2.0E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS18575 713b70ed5bce582cf6864703072297b0 363 PIRSF PIRSF001455 11 347 4.6E-96 T 06-07-2017 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 BWK49_RS18575 713b70ed5bce582cf6864703072297b0 363 Gene3D G3DSA:1.20.1090.10 174 354 4.7E-60 T 06-07-2017 BWK49_RS18575 713b70ed5bce582cf6864703072297b0 363 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 7 357 37.615 T 06-07-2017 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 BWK49_RS18575 713b70ed5bce582cf6864703072297b0 363 Gene3D G3DSA:3.40.50.1970 14 173 2.5E-53 T 06-07-2017 BWK49_RS18575 713b70ed5bce582cf6864703072297b0 363 SUPERFAMILY SSF56796 9 355 3.01E-100 T 06-07-2017 BWK49_RS18575 713b70ed5bce582cf6864703072297b0 363 Pfam PF01761 3-dehydroquinate synthase 68 324 3.3E-93 T 06-07-2017 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 BWK49_RS18575 713b70ed5bce582cf6864703072297b0 363 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 17 340 8.7E-104 T 06-07-2017 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 BWK49_RS14865 eaafcb76cbbb085bb88eaf7be12be7de 129 Gene3D G3DSA:2.30.110.10 34 104 4.3E-7 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 BWK49_RS14865 eaafcb76cbbb085bb88eaf7be12be7de 129 SUPERFAMILY SSF50475 37 109 7.46E-7 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 BWK49_RS14865 eaafcb76cbbb085bb88eaf7be12be7de 129 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 23 125 6.1E-29 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 BWK49_RS14865 eaafcb76cbbb085bb88eaf7be12be7de 129 Pfam PF04075 Domain of unknown function (DUF385) 8 128 4.7E-33 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 BWK49_RS02460 5aa18f6ebb49ddc4d004aa3a410941f6 427 SUPERFAMILY SSF53383 61 412 1.36E-39 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase BWK49_RS02460 5aa18f6ebb49ddc4d004aa3a410941f6 427 Pfam PF12897 Alanine-glyoxylate amino-transferase 8 422 5.9E-185 T 06-07-2017 IPR024551 Aminotransferase, putative BWK49_RS02460 5aa18f6ebb49ddc4d004aa3a410941f6 427 Gene3D G3DSA:3.90.1150.10 251 422 1.1E-52 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 BWK49_RS02460 5aa18f6ebb49ddc4d004aa3a410941f6 427 Gene3D G3DSA:3.90.1150.10 2 165 5.7E-47 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 BWK49_RS16205 eca0299ffc62bf5d142c5e40a57bc5cf 868 SMART SM00421 803 860 1.6E-18 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS16205 eca0299ffc62bf5d142c5e40a57bc5cf 868 SUPERFAMILY SSF52540 7 212 8.26E-13 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS16205 eca0299ffc62bf5d142c5e40a57bc5cf 868 Gene3D G3DSA:1.10.10.10 801 860 1.2E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS16205 eca0299ffc62bf5d142c5e40a57bc5cf 868 ProSitePatterns PS00622 LuxR-type HTH domain signature. 820 847 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS16205 eca0299ffc62bf5d142c5e40a57bc5cf 868 SUPERFAMILY SSF46894 799 860 9.52E-17 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 BWK49_RS16205 eca0299ffc62bf5d142c5e40a57bc5cf 868 Pfam PF00196 Bacterial regulatory proteins, luxR family 807 859 3.6E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS16205 eca0299ffc62bf5d142c5e40a57bc5cf 868 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 806 820 6.8E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS16205 eca0299ffc62bf5d142c5e40a57bc5cf 868 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 836 848 6.8E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS16205 eca0299ffc62bf5d142c5e40a57bc5cf 868 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 820 836 6.8E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS20450 04248171758f9493d29dc32368589bf3 479 Pfam PF13408 Recombinase zinc beta ribbon domain 283 342 6.0E-9 T 06-07-2017 IPR025827 Recombinase zinc beta ribbon domain BWK49_RS20450 04248171758f9493d29dc32368589bf3 479 Pfam PF07508 Recombinase 184 269 1.1E-10 T 06-07-2017 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 BWK49_RS20450 04248171758f9493d29dc32368589bf3 479 SMART SM00857 16 165 2.3E-40 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 BWK49_RS20450 04248171758f9493d29dc32368589bf3 479 Pfam PF00239 Resolvase, N terminal domain 16 164 5.9E-27 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 BWK49_RS20450 04248171758f9493d29dc32368589bf3 479 SUPERFAMILY SSF53041 16 164 3.27E-25 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 BWK49_RS20450 04248171758f9493d29dc32368589bf3 479 Gene3D G3DSA:3.40.50.1390 16 145 1.3E-20 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 BWK49_RS00105 78b86cf449ba3a1b6908cf6762bbad86 626 SUPERFAMILY SSF56112 8 275 1.75E-78 T 06-07-2017 IPR011009 Protein kinase-like domain BWK49_RS00105 78b86cf449ba3a1b6908cf6762bbad86 626 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 134 146 - T 06-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 BWK49_RS00105 78b86cf449ba3a1b6908cf6762bbad86 626 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 17 40 - T 06-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 BWK49_RS00105 78b86cf449ba3a1b6908cf6762bbad86 626 SMART SM00220 11 274 3.6E-69 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 BWK49_RS00105 78b86cf449ba3a1b6908cf6762bbad86 626 Pfam PF03793 PASTA domain 360 422 1.0E-13 T 06-07-2017 IPR005543 PASTA domain BWK49_RS00105 78b86cf449ba3a1b6908cf6762bbad86 626 Pfam PF03793 PASTA domain 496 557 6.8E-13 T 06-07-2017 IPR005543 PASTA domain BWK49_RS00105 78b86cf449ba3a1b6908cf6762bbad86 626 Pfam PF03793 PASTA domain 428 489 1.6E-9 T 06-07-2017 IPR005543 PASTA domain BWK49_RS00105 78b86cf449ba3a1b6908cf6762bbad86 626 Pfam PF03793 PASTA domain 562 624 1.9E-9 T 06-07-2017 IPR005543 PASTA domain BWK49_RS00105 78b86cf449ba3a1b6908cf6762bbad86 626 Pfam PF00069 Protein kinase domain 11 265 2.5E-50 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 BWK49_RS00105 78b86cf449ba3a1b6908cf6762bbad86 626 Gene3D G3DSA:3.30.200.20 3 79 1.5E-30 T 06-07-2017 BWK49_RS00105 78b86cf449ba3a1b6908cf6762bbad86 626 Gene3D G3DSA:1.10.510.10 80 271 3.8E-55 T 06-07-2017 BWK49_RS00105 78b86cf449ba3a1b6908cf6762bbad86 626 SMART SM00740 491 557 9.2E-12 T 06-07-2017 IPR005543 PASTA domain BWK49_RS00105 78b86cf449ba3a1b6908cf6762bbad86 626 SMART SM00740 356 422 1.7E-14 T 06-07-2017 IPR005543 PASTA domain BWK49_RS00105 78b86cf449ba3a1b6908cf6762bbad86 626 SMART SM00740 558 626 1.3E-8 T 06-07-2017 IPR005543 PASTA domain BWK49_RS00105 78b86cf449ba3a1b6908cf6762bbad86 626 SMART SM00740 423 490 1.8E-13 T 06-07-2017 IPR005543 PASTA domain BWK49_RS09350 741b26f7257ac4c4005f515ca77dc9b1 390 SUPERFAMILY SSF53098 169 224 2.45E-20 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS09350 741b26f7257ac4c4005f515ca77dc9b1 390 SUPERFAMILY SSF53098 258 354 2.45E-20 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS09350 741b26f7257ac4c4005f515ca77dc9b1 390 Pfam PF00665 Integrase core domain 170 314 8.7E-14 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 BWK49_RS09350 741b26f7257ac4c4005f515ca77dc9b1 390 Gene3D G3DSA:3.30.420.10 259 351 7.5E-25 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS09350 741b26f7257ac4c4005f515ca77dc9b1 390 Gene3D G3DSA:3.30.420.10 166 223 7.5E-25 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS16495 741b26f7257ac4c4005f515ca77dc9b1 390 SUPERFAMILY SSF53098 169 224 2.45E-20 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS16495 741b26f7257ac4c4005f515ca77dc9b1 390 SUPERFAMILY SSF53098 258 354 2.45E-20 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS16495 741b26f7257ac4c4005f515ca77dc9b1 390 Pfam PF00665 Integrase core domain 170 314 8.7E-14 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 BWK49_RS16495 741b26f7257ac4c4005f515ca77dc9b1 390 Gene3D G3DSA:3.30.420.10 259 351 7.5E-25 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS16495 741b26f7257ac4c4005f515ca77dc9b1 390 Gene3D G3DSA:3.30.420.10 166 223 7.5E-25 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS20675 741b26f7257ac4c4005f515ca77dc9b1 390 SUPERFAMILY SSF53098 169 224 2.45E-20 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS20675 741b26f7257ac4c4005f515ca77dc9b1 390 SUPERFAMILY SSF53098 258 354 2.45E-20 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS20675 741b26f7257ac4c4005f515ca77dc9b1 390 Pfam PF00665 Integrase core domain 170 314 8.7E-14 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 BWK49_RS20675 741b26f7257ac4c4005f515ca77dc9b1 390 Gene3D G3DSA:3.30.420.10 259 351 7.5E-25 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS20675 741b26f7257ac4c4005f515ca77dc9b1 390 Gene3D G3DSA:3.30.420.10 166 223 7.5E-25 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS29045 741b26f7257ac4c4005f515ca77dc9b1 390 SUPERFAMILY SSF53098 169 224 2.45E-20 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS29045 741b26f7257ac4c4005f515ca77dc9b1 390 SUPERFAMILY SSF53098 258 354 2.45E-20 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS29045 741b26f7257ac4c4005f515ca77dc9b1 390 Pfam PF00665 Integrase core domain 170 314 8.7E-14 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 BWK49_RS29045 741b26f7257ac4c4005f515ca77dc9b1 390 Gene3D G3DSA:3.30.420.10 259 351 7.5E-25 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS29045 741b26f7257ac4c4005f515ca77dc9b1 390 Gene3D G3DSA:3.30.420.10 166 223 7.5E-25 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS04885 741b26f7257ac4c4005f515ca77dc9b1 390 SUPERFAMILY SSF53098 169 224 2.45E-20 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS04885 741b26f7257ac4c4005f515ca77dc9b1 390 SUPERFAMILY SSF53098 258 354 2.45E-20 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS04885 741b26f7257ac4c4005f515ca77dc9b1 390 Pfam PF00665 Integrase core domain 170 314 8.7E-14 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 BWK49_RS04885 741b26f7257ac4c4005f515ca77dc9b1 390 Gene3D G3DSA:3.30.420.10 259 351 7.5E-25 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS04885 741b26f7257ac4c4005f515ca77dc9b1 390 Gene3D G3DSA:3.30.420.10 166 223 7.5E-25 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS09495 ad4ffe0fe1e4c859d0f276926426f8f8 502 Gene3D G3DSA:3.40.50.980 42 169 5.2E-20 T 06-07-2017 BWK49_RS09495 ad4ffe0fe1e4c859d0f276926426f8f8 502 Gene3D G3DSA:3.40.50.980 188 310 3.5E-28 T 06-07-2017 BWK49_RS09495 ad4ffe0fe1e4c859d0f276926426f8f8 502 Gene3D G3DSA:3.30.300.30 399 497 5.4E-25 T 06-07-2017 BWK49_RS09495 ad4ffe0fe1e4c859d0f276926426f8f8 502 Gene3D G3DSA:2.30.38.10 323 396 5.1E-11 T 06-07-2017 BWK49_RS09495 ad4ffe0fe1e4c859d0f276926426f8f8 502 Pfam PF13193 AMP-binding enzyme C-terminal domain 412 490 3.1E-15 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS09495 ad4ffe0fe1e4c859d0f276926426f8f8 502 Pfam PF00501 AMP-binding enzyme 41 403 2.2E-57 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS09495 ad4ffe0fe1e4c859d0f276926426f8f8 502 SUPERFAMILY SSF56801 24 498 7.2E-102 T 06-07-2017 BWK49_RS24555 5e3bd7b2ae858bf071e2603932cc28ae 301 Gene3D G3DSA:3.40.50.1820 7 296 7.4E-61 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS24555 5e3bd7b2ae858bf071e2603932cc28ae 301 Pfam PF00561 alpha/beta hydrolase fold 26 280 9.9E-21 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS24555 5e3bd7b2ae858bf071e2603932cc28ae 301 SUPERFAMILY SSF53474 5 295 7.16E-56 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS19215 b9d821360ec17097fac793d79f589c45 258 SUPERFAMILY SSF69118 18 241 5.42E-33 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 BWK49_RS19215 b9d821360ec17097fac793d79f589c45 258 Pfam PF02627 Carboxymuconolactone decarboxylase family 160 236 9.2E-8 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 BWK49_RS19215 b9d821360ec17097fac793d79f589c45 258 Pfam PF02627 Carboxymuconolactone decarboxylase family 22 95 1.2E-9 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 BWK49_RS19215 b9d821360ec17097fac793d79f589c45 258 Gene3D G3DSA:1.20.1290.10 132 247 1.5E-7 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 BWK49_RS19215 b9d821360ec17097fac793d79f589c45 258 Gene3D G3DSA:1.20.1290.10 19 94 1.1E-13 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 BWK49_RS01450 bbd9e0f697e48a27cae7840268a0ca90 342 Pfam PF02470 MlaD protein 38 114 6.6E-15 T 06-07-2017 IPR003399 Mce/MlaD BWK49_RS01450 bbd9e0f697e48a27cae7840268a0ca90 342 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 11 295 8.0E-74 T 06-07-2017 IPR005693 Virulence factor Mce protein BWK49_RS01450 bbd9e0f697e48a27cae7840268a0ca90 342 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 147 275 4.0E-7 T 06-07-2017 IPR024516 Mammalian cell entry, C-terminal BWK49_RS09550 38905ee4bfa61293306ac9a9afa6e2ad 377 SUPERFAMILY SSF50022 33 145 9.17E-32 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS09550 38905ee4bfa61293306ac9a9afa6e2ad 377 Gene3D G3DSA:2.102.10.10 38 149 9.6E-29 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS09550 38905ee4bfa61293306ac9a9afa6e2ad 377 Pfam PF00355 Rieske [2Fe-2S] domain 39 119 2.0E-17 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS09550 38905ee4bfa61293306ac9a9afa6e2ad 377 SUPERFAMILY SSF55961 156 326 3.74E-21 T 06-07-2017 BWK49_RS12790 d4e049ea49d2a46cb389e03acb5dba7e 592 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 399 410 4.9E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS12790 d4e049ea49d2a46cb389e03acb5dba7e 592 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 473 492 4.9E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS12790 d4e049ea49d2a46cb389e03acb5dba7e 592 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 453 461 4.9E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS12790 d4e049ea49d2a46cb389e03acb5dba7e 592 Gene3D G3DSA:3.40.50.1820 4 299 7.5E-48 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS12790 d4e049ea49d2a46cb389e03acb5dba7e 592 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 460 488 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS12790 d4e049ea49d2a46cb389e03acb5dba7e 592 Gene3D G3DSA:3.40.50.720 326 560 1.2E-66 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS12790 d4e049ea49d2a46cb389e03acb5dba7e 592 SUPERFAMILY SSF53474 6 296 6.65E-44 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS12790 d4e049ea49d2a46cb389e03acb5dba7e 592 Pfam PF00561 alpha/beta hydrolase fold 31 285 1.4E-27 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS12790 d4e049ea49d2a46cb389e03acb5dba7e 592 SUPERFAMILY SSF51735 320 560 1.27E-62 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS12790 d4e049ea49d2a46cb389e03acb5dba7e 592 Pfam PF00106 short chain dehydrogenase 326 514 5.0E-50 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS12790 d4e049ea49d2a46cb389e03acb5dba7e 592 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 494 511 1.4E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS12790 d4e049ea49d2a46cb389e03acb5dba7e 592 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 399 410 1.4E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS12790 d4e049ea49d2a46cb389e03acb5dba7e 592 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 447 463 1.4E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS12790 d4e049ea49d2a46cb389e03acb5dba7e 592 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 325 342 1.4E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS12790 d4e049ea49d2a46cb389e03acb5dba7e 592 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 473 492 1.4E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS07790 0831473a6bc6dc57bdea3ca50b606606 429 Pfam PF00464 Serine hydroxymethyltransferase 5 386 1.0E-155 T 06-07-2017 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 BWK49_RS07790 0831473a6bc6dc57bdea3ca50b606606 429 PIRSF PIRSF000412 1 423 2.2E-147 T 06-07-2017 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 BWK49_RS07790 0831473a6bc6dc57bdea3ca50b606606 429 Gene3D G3DSA:3.40.640.10 34 280 1.2E-98 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 BWK49_RS07790 0831473a6bc6dc57bdea3ca50b606606 429 Gene3D G3DSA:3.90.1150.10 281 419 1.7E-47 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 BWK49_RS07790 0831473a6bc6dc57bdea3ca50b606606 429 SUPERFAMILY SSF53383 3 419 1.86E-165 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase BWK49_RS07790 0831473a6bc6dc57bdea3ca50b606606 429 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 4 419 48.2 T 06-07-2017 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 BWK49_RS22425 bf37ff037d5a075270d07e5d338aa84b 361 Gene3D G3DSA:3.40.50.150 120 359 1.7E-68 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS22425 bf37ff037d5a075270d07e5d338aa84b 361 SUPERFAMILY SSF46785 31 114 1.43E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS22425 bf37ff037d5a075270d07e5d338aa84b 361 PIRSF PIRSF005739 14 360 9.0E-50 T 06-07-2017 IPR016461 O-methyltransferase COMT-type GO:0008168 BWK49_RS22425 bf37ff037d5a075270d07e5d338aa84b 361 Gene3D G3DSA:1.10.10.10 29 119 2.9E-33 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS22425 bf37ff037d5a075270d07e5d338aa84b 361 SUPERFAMILY SSF53335 116 358 3.82E-51 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS22425 bf37ff037d5a075270d07e5d338aa84b 361 Pfam PF16864 Dimerisation domain 37 110 1.2E-10 T 06-07-2017 IPR031725 Acetylserotonin O-methyltransferase, dimerisation domain BWK49_RS22425 bf37ff037d5a075270d07e5d338aa84b 361 Pfam PF00891 O-methyltransferase 130 342 4.9E-48 T 06-07-2017 IPR001077 O-methyltransferase, family 2 GO:0008171 BWK49_RS17930 31782739704941532e21bdd8498356d4 269 Pfam PF00378 Enoyl-CoA hydratase/isomerase 12 267 2.1E-47 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 BWK49_RS17930 31782739704941532e21bdd8498356d4 269 Gene3D G3DSA:3.90.226.10 4 266 1.5E-67 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS17930 31782739704941532e21bdd8498356d4 269 SUPERFAMILY SSF52096 3 267 2.49E-69 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS17930 31782739704941532e21bdd8498356d4 269 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 106 126 - T 06-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 BWK49_RS03895 0a4e749c29ea1ccde78d7495074303dd 712 Gene3D G3DSA:2.130.10.120 79 432 5.4E-112 T 06-07-2017 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 BWK49_RS03895 0a4e749c29ea1ccde78d7495074303dd 712 SUPERFAMILY SSF53474 437 684 5.76E-43 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS03895 0a4e749c29ea1ccde78d7495074303dd 712 Pfam PF02897 Prolyl oligopeptidase, N-terminal beta-propeller domain 11 429 5.7E-116 T 06-07-2017 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 BWK49_RS03895 0a4e749c29ea1ccde78d7495074303dd 712 Pfam PF00326 Prolyl oligopeptidase family 485 701 1.9E-63 T 06-07-2017 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 BWK49_RS03895 0a4e749c29ea1ccde78d7495074303dd 712 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 470 488 1.1E-56 T 06-07-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 BWK49_RS03895 0a4e749c29ea1ccde78d7495074303dd 712 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 524 543 1.1E-56 T 06-07-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 BWK49_RS03895 0a4e749c29ea1ccde78d7495074303dd 712 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 613 628 1.1E-56 T 06-07-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 BWK49_RS03895 0a4e749c29ea1ccde78d7495074303dd 712 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 554 574 1.1E-56 T 06-07-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 BWK49_RS03895 0a4e749c29ea1ccde78d7495074303dd 712 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 631 653 1.1E-56 T 06-07-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 BWK49_RS03895 0a4e749c29ea1ccde78d7495074303dd 712 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 496 520 1.1E-56 T 06-07-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 BWK49_RS03895 0a4e749c29ea1ccde78d7495074303dd 712 SUPERFAMILY SSF50993 9 435 9.42E-90 T 06-07-2017 BWK49_RS03895 0a4e749c29ea1ccde78d7495074303dd 712 Gene3D G3DSA:3.40.50.1820 449 697 3.5E-29 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS14755 2f2ee746c25018ce7585d2a8fab25f54 277 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 1.9E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS14755 2f2ee746c25018ce7585d2a8fab25f54 277 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 1.9E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS14755 2f2ee746c25018ce7585d2a8fab25f54 277 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS14755 2f2ee746c25018ce7585d2a8fab25f54 277 Pfam PF00106 short chain dehydrogenase 2 192 2.6E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS14755 2f2ee746c25018ce7585d2a8fab25f54 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 1.1E-20 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS14755 2f2ee746c25018ce7585d2a8fab25f54 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 1.1E-20 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS14755 2f2ee746c25018ce7585d2a8fab25f54 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 1.1E-20 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS14755 2f2ee746c25018ce7585d2a8fab25f54 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 139 1.1E-20 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS14755 2f2ee746c25018ce7585d2a8fab25f54 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 1.1E-20 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS14755 2f2ee746c25018ce7585d2a8fab25f54 277 SUPERFAMILY SSF51735 2 253 2.44E-52 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS14755 2f2ee746c25018ce7585d2a8fab25f54 277 Gene3D G3DSA:3.40.50.720 2 253 4.8E-53 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS00785 12ee9862e3dbd2181b193d1597c02819 251 SUPERFAMILY SSF56784 13 220 6.03E-38 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS00785 12ee9862e3dbd2181b193d1597c02819 251 TIGRFAM TIGR01493 HAD-SF-IA-v2: HAD hydrolase, family IA, variant 2 16 201 6.1E-18 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 BWK49_RS00785 12ee9862e3dbd2181b193d1597c02819 251 TIGRFAM TIGR01428 HAD_type_II: haloacid dehalogenase, type II 14 215 9.0E-43 T 06-07-2017 IPR006328 Haloacid dehalogenase, type II GO:0008152|GO:0019120 KEGG: 00361+3.8.1.2|KEGG: 00625+3.8.1.2|MetaCyc: PWY-7425 BWK49_RS00785 12ee9862e3dbd2181b193d1597c02819 251 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 13 24 1.6E-10 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 BWK49_RS00785 12ee9862e3dbd2181b193d1597c02819 251 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 199 212 1.6E-10 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 BWK49_RS00785 12ee9862e3dbd2181b193d1597c02819 251 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 172 192 1.6E-10 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 BWK49_RS00785 12ee9862e3dbd2181b193d1597c02819 251 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 154 170 1.6E-10 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 BWK49_RS00785 12ee9862e3dbd2181b193d1597c02819 251 Pfam PF00702 haloacid dehalogenase-like hydrolase 14 203 5.1E-6 T 06-07-2017 BWK49_RS00785 12ee9862e3dbd2181b193d1597c02819 251 Gene3D G3DSA:3.40.50.1000 13 218 6.2E-29 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS07030 2f493fe7c02223fd44049d92b39c5e56 282 SUPERFAMILY SSF51430 6 266 4.58E-88 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain BWK49_RS07030 2f493fe7c02223fd44049d92b39c5e56 282 Gene3D G3DSA:3.20.20.100 5 275 3.2E-98 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain BWK49_RS07030 2f493fe7c02223fd44049d92b39c5e56 282 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 127 144 - T 06-07-2017 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 BWK49_RS07030 2f493fe7c02223fd44049d92b39c5e56 282 PRINTS PR00069 Aldo-keto reductase signature 127 144 2.7E-46 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 BWK49_RS07030 2f493fe7c02223fd44049d92b39c5e56 282 PRINTS PR00069 Aldo-keto reductase signature 198 222 2.7E-46 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 BWK49_RS07030 2f493fe7c02223fd44049d92b39c5e56 282 PRINTS PR00069 Aldo-keto reductase signature 93 111 2.7E-46 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 BWK49_RS07030 2f493fe7c02223fd44049d92b39c5e56 282 PRINTS PR00069 Aldo-keto reductase signature 37 61 2.7E-46 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 BWK49_RS07030 2f493fe7c02223fd44049d92b39c5e56 282 PRINTS PR00069 Aldo-keto reductase signature 161 190 2.7E-46 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 BWK49_RS07030 2f493fe7c02223fd44049d92b39c5e56 282 PIRSF PIRSF000097 2 280 1.1E-85 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 BWK49_RS07030 2f493fe7c02223fd44049d92b39c5e56 282 Pfam PF00248 Aldo/keto reductase family 24 263 1.1E-41 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain BWK49_RS23135 25764388e97cdf0f3f2a53d6cbd9e7b6 171 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 8 159 32.877 T 06-07-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 BWK49_RS23135 25764388e97cdf0f3f2a53d6cbd9e7b6 171 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 8 162 4.9E-67 T 06-07-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 BWK49_RS23135 25764388e97cdf0f3f2a53d6cbd9e7b6 171 Pfam PF00731 AIR carboxylase 7 153 2.1E-65 T 06-07-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 BWK49_RS23135 25764388e97cdf0f3f2a53d6cbd9e7b6 171 SMART SM01001 6 155 6.4E-94 T 06-07-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 BWK49_RS23135 25764388e97cdf0f3f2a53d6cbd9e7b6 171 PIRSF PIRSF001338 3 166 6.1E-69 T 06-07-2017 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 BWK49_RS23135 25764388e97cdf0f3f2a53d6cbd9e7b6 171 SUPERFAMILY SSF52255 7 165 5.1E-66 T 06-07-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 BWK49_RS23135 25764388e97cdf0f3f2a53d6cbd9e7b6 171 Gene3D G3DSA:3.40.50.7700 2 164 4.2E-74 T 06-07-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 BWK49_RS13560 244d9fb38c5c5ffeffbb8fea2f2095e0 267 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 263 4.3E-45 T 06-07-2017 BWK49_RS13560 244d9fb38c5c5ffeffbb8fea2f2095e0 267 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS13560 244d9fb38c5c5ffeffbb8fea2f2095e0 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 9.6E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS13560 244d9fb38c5c5ffeffbb8fea2f2095e0 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 9.6E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS13560 244d9fb38c5c5ffeffbb8fea2f2095e0 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 9.6E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS13560 244d9fb38c5c5ffeffbb8fea2f2095e0 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 9.6E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS13560 244d9fb38c5c5ffeffbb8fea2f2095e0 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 228 248 9.6E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS13560 244d9fb38c5c5ffeffbb8fea2f2095e0 267 SUPERFAMILY SSF51735 7 263 1.42E-61 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS13560 244d9fb38c5c5ffeffbb8fea2f2095e0 267 Gene3D G3DSA:3.40.50.720 2 263 5.6E-62 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS08395 3048a0c005dc75002a8716ecb12ace8d 149 Gene3D G3DSA:3.10.129.10 4 135 5.2E-24 T 06-07-2017 IPR029069 HotDog domain BWK49_RS08395 3048a0c005dc75002a8716ecb12ace8d 149 SUPERFAMILY SSF54637 8 140 4.91E-23 T 06-07-2017 IPR029069 HotDog domain BWK49_RS08395 3048a0c005dc75002a8716ecb12ace8d 149 Pfam PF01575 MaoC like domain 20 121 1.1E-8 T 06-07-2017 IPR002539 MaoC-like domain BWK49_RS24270 8a193885c51db5809ce52818dda63332 296 Pfam PF03781 Sulfatase-modifying factor enzyme 1 4 291 3.3E-84 T 06-07-2017 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 BWK49_RS24270 8a193885c51db5809ce52818dda63332 296 SUPERFAMILY SSF56436 4 291 1.17E-89 T 06-07-2017 IPR016187 C-type lectin fold BWK49_RS24270 8a193885c51db5809ce52818dda63332 296 Gene3D G3DSA:3.90.1580.10 4 291 1.4E-89 T 06-07-2017 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 BWK49_RS13525 b7cd1cd4ea911e1a67e9e5e4e04c1851 366 Gene3D G3DSA:3.90.480.10 223 295 8.7E-28 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 BWK49_RS13525 b7cd1cd4ea911e1a67e9e5e4e04c1851 366 Gene3D G3DSA:3.90.480.10 18 86 8.7E-28 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 BWK49_RS13525 b7cd1cd4ea911e1a67e9e5e4e04c1851 366 SUPERFAMILY SSF56014 91 198 1.83E-5 T 06-07-2017 BWK49_RS13525 b7cd1cd4ea911e1a67e9e5e4e04c1851 366 SUPERFAMILY SSF55124 176 294 2.78E-22 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 BWK49_RS13525 b7cd1cd4ea911e1a67e9e5e4e04c1851 366 SUPERFAMILY SSF55124 5 84 6.05E-20 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 BWK49_RS13525 b7cd1cd4ea911e1a67e9e5e4e04c1851 366 TIGRFAM TIGR02435 CobG: precorrin-3B synthase 7 361 1.2E-99 T 06-07-2017 IPR012798 Cobalamin (vitamin B12) biosynthesis CobG-like BWK49_RS13525 b7cd1cd4ea911e1a67e9e5e4e04c1851 366 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 21 80 1.3E-11 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 BWK49_RS08910 38dcd954499dcd34a573fe9f8513e569 76 SUPERFAMILY SSF143800 1 67 4.32E-26 T 06-07-2017 BWK49_RS08910 38dcd954499dcd34a573fe9f8513e569 76 ProSitePatterns PS01143 Ribosomal protein L31 signature. 36 57 - T 06-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS08910 38dcd954499dcd34a573fe9f8513e569 76 Hamap MF_00501 50S ribosomal protein L31 [rpmE]. 1 69 30.883 T 06-07-2017 IPR027491 Ribosomal protein L31 type A GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS08910 38dcd954499dcd34a573fe9f8513e569 76 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 67 3.4E-33 T 06-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS08910 38dcd954499dcd34a573fe9f8513e569 76 PRINTS PR01249 Ribosomal protein L31 signature 47 65 1.6E-22 T 06-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS08910 38dcd954499dcd34a573fe9f8513e569 76 PRINTS PR01249 Ribosomal protein L31 signature 32 47 1.6E-22 T 06-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS08910 38dcd954499dcd34a573fe9f8513e569 76 PRINTS PR01249 Ribosomal protein L31 signature 2 19 1.6E-22 T 06-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS08910 38dcd954499dcd34a573fe9f8513e569 76 Pfam PF01197 Ribosomal protein L31 1 66 1.2E-32 T 06-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS28225 639aaa7e09252bb07c885bd1236ad51c 218 SMART SM00421 152 209 6.4E-22 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS28225 639aaa7e09252bb07c885bd1236ad51c 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 4.2E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS28225 639aaa7e09252bb07c885bd1236ad51c 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 4.2E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS28225 639aaa7e09252bb07c885bd1236ad51c 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 4.2E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS28225 639aaa7e09252bb07c885bd1236ad51c 218 SUPERFAMILY SSF46894 147 215 4.42E-20 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 BWK49_RS28225 639aaa7e09252bb07c885bd1236ad51c 218 ProSitePatterns PS00622 LuxR-type HTH domain signature. 169 196 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS28225 639aaa7e09252bb07c885bd1236ad51c 218 Gene3D G3DSA:1.10.10.10 124 216 1.7E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS28225 639aaa7e09252bb07c885bd1236ad51c 218 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 209 3.3E-17 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS28225 639aaa7e09252bb07c885bd1236ad51c 218 Gene3D G3DSA:3.40.50.2300 7 123 3.5E-33 T 06-07-2017 BWK49_RS28225 639aaa7e09252bb07c885bd1236ad51c 218 SUPERFAMILY SSF52172 8 136 1.27E-30 T 06-07-2017 IPR011006 CheY-like superfamily BWK49_RS28225 639aaa7e09252bb07c885bd1236ad51c 218 SMART SM00448 8 118 2.2E-29 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 BWK49_RS28225 639aaa7e09252bb07c885bd1236ad51c 218 Pfam PF00072 Response regulator receiver domain 10 118 3.6E-25 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 BWK49_RS14740 02b407d2d4dbe2eeb2bbe2203de82842 176 Pfam PF01817 Chorismate mutase type II 23 91 2.0E-7 T 06-07-2017 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 BWK49_RS14740 02b407d2d4dbe2eeb2bbe2203de82842 176 SMART SM00830 13 93 2.9E-10 T 06-07-2017 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 BWK49_RS14740 02b407d2d4dbe2eeb2bbe2203de82842 176 Gene3D G3DSA:1.20.59.10 23 79 5.4E-7 T 06-07-2017 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 BWK49_RS14740 02b407d2d4dbe2eeb2bbe2203de82842 176 TIGRFAM TIGR01806 CM_mono2: putative chorismate mutase 18 129 6.7E-35 T 06-07-2017 IPR008240 Chorismate mutase, periplasmic KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 BWK49_RS14740 02b407d2d4dbe2eeb2bbe2203de82842 176 PIRSF PIRSF026640 3 176 1.4E-59 T 06-07-2017 IPR008240 Chorismate mutase, periplasmic KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 BWK49_RS14740 02b407d2d4dbe2eeb2bbe2203de82842 176 SUPERFAMILY SSF48600 20 174 1.42E-36 T 06-07-2017 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 BWK49_RS20605 edb7cf6bf193e0b9087d55dd950fb9e8 99 Pfam PF00934 PE family 2 92 1.1E-31 T 06-07-2017 IPR000084 PE-PGRS family, N-terminal BWK49_RS20605 edb7cf6bf193e0b9087d55dd950fb9e8 99 SUPERFAMILY SSF140459 8 84 1.33E-23 T 06-07-2017 BWK49_RS05990 ab1a79c975fbf7fa76431bef86d6d4e3 64 Gene3D G3DSA:3.30.70.20 1 64 5.3E-17 T 06-07-2017 BWK49_RS05990 ab1a79c975fbf7fa76431bef86d6d4e3 64 SUPERFAMILY SSF54862 2 63 2.27E-13 T 06-07-2017 BWK49_RS05990 ab1a79c975fbf7fa76431bef86d6d4e3 64 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 5 62 4.3E-13 T 06-07-2017 BWK49_RS05990 ab1a79c975fbf7fa76431bef86d6d4e3 64 PRINTS PR00352 3Fe-4S ferredoxin signature 5 16 4.5E-6 T 06-07-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 BWK49_RS05990 ab1a79c975fbf7fa76431bef86d6d4e3 64 PRINTS PR00352 3Fe-4S ferredoxin signature 16 26 4.5E-6 T 06-07-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 BWK49_RS05990 ab1a79c975fbf7fa76431bef86d6d4e3 64 PRINTS PR00352 3Fe-4S ferredoxin signature 48 60 4.5E-6 T 06-07-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 BWK49_RS02255 09112a3bdf7084c8051ceffd5256a2a6 412 Gene3D G3DSA:3.60.15.10 24 113 1.0E-37 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS02255 09112a3bdf7084c8051ceffd5256a2a6 412 Gene3D G3DSA:3.60.15.10 153 276 1.0E-37 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS02255 09112a3bdf7084c8051ceffd5256a2a6 412 SUPERFAMILY SSF56281 22 400 3.81E-66 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS02255 09112a3bdf7084c8051ceffd5256a2a6 412 SMART SM00849 36 246 4.7E-19 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS02255 09112a3bdf7084c8051ceffd5256a2a6 412 Pfam PF00753 Metallo-beta-lactamase superfamily 34 246 1.8E-13 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS02255 09112a3bdf7084c8051ceffd5256a2a6 412 Pfam PF14863 Alkyl sulfatase dimerisation 298 406 4.6E-12 T 06-07-2017 IPR029228 Alkyl sulfatase dimerisation domain GO:0046983 BWK49_RS21290 a4368fe76490725140a8ffab35c8f61a 346 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 06-07-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 BWK49_RS21290 a4368fe76490725140a8ffab35c8f61a 346 SUPERFAMILY SSF50129 7 171 1.45E-56 T 06-07-2017 IPR011032 GroES-like BWK49_RS21290 a4368fe76490725140a8ffab35c8f61a 346 Gene3D G3DSA:3.90.180.10 2 176 6.9E-69 T 06-07-2017 IPR011032 GroES-like BWK49_RS21290 a4368fe76490725140a8ffab35c8f61a 346 Pfam PF00107 Zinc-binding dehydrogenase 185 307 8.2E-17 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 BWK49_RS21290 a4368fe76490725140a8ffab35c8f61a 346 SMART SM00829 11 341 2.2E-6 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 BWK49_RS21290 a4368fe76490725140a8ffab35c8f61a 346 SUPERFAMILY SSF51735 148 311 7.14E-37 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS21290 a4368fe76490725140a8ffab35c8f61a 346 Gene3D G3DSA:3.40.50.720 177 291 5.3E-15 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS21290 a4368fe76490725140a8ffab35c8f61a 346 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 143 3.1E-30 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 BWK49_RS28545 05ffd36b8726e6250b01cabd68c4f978 229 SMART SM00100 15 134 1.1E-17 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain BWK49_RS28545 05ffd36b8726e6250b01cabd68c4f978 229 Gene3D G3DSA:1.10.10.10 148 226 8.2E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS28545 05ffd36b8726e6250b01cabd68c4f978 229 Pfam PF13545 Crp-like helix-turn-helix domain 152 224 1.8E-14 T 06-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 BWK49_RS28545 05ffd36b8726e6250b01cabd68c4f978 229 Gene3D G3DSA:2.60.120.10 19 140 2.9E-29 T 06-07-2017 IPR014710 RmlC-like jelly roll fold BWK49_RS28545 05ffd36b8726e6250b01cabd68c4f978 229 SUPERFAMILY SSF51206 19 141 1.7E-30 T 06-07-2017 IPR018490 Cyclic nucleotide-binding-like BWK49_RS28545 05ffd36b8726e6250b01cabd68c4f978 229 Pfam PF00027 Cyclic nucleotide-binding domain 34 117 1.2E-19 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain BWK49_RS28545 05ffd36b8726e6250b01cabd68c4f978 229 SMART SM00419 170 218 1.5E-6 T 06-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 BWK49_RS28545 05ffd36b8726e6250b01cabd68c4f978 229 SUPERFAMILY SSF46785 149 226 3.25E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS10005 54cdb66f212ef6ad2bdf601275bc9452 367 SUPERFAMILY SSF88697 280 365 4.64E-15 T 06-07-2017 IPR015947 PUA-like domain BWK49_RS10005 54cdb66f212ef6ad2bdf601275bc9452 367 SUPERFAMILY SSF53633 14 258 5.5E-56 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase BWK49_RS10005 54cdb66f212ef6ad2bdf601275bc9452 367 SMART SM00359 280 359 2.2E-15 T 06-07-2017 IPR002478 PUA domain GO:0003723 BWK49_RS10005 54cdb66f212ef6ad2bdf601275bc9452 367 PRINTS PR00474 Glutamate 5-kinase family signature 83 111 1.9E-50 T 06-07-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 BWK49_RS10005 54cdb66f212ef6ad2bdf601275bc9452 367 PRINTS PR00474 Glutamate 5-kinase family signature 155 182 1.9E-50 T 06-07-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 BWK49_RS10005 54cdb66f212ef6ad2bdf601275bc9452 367 PRINTS PR00474 Glutamate 5-kinase family signature 49 63 1.9E-50 T 06-07-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 BWK49_RS10005 54cdb66f212ef6ad2bdf601275bc9452 367 PRINTS PR00474 Glutamate 5-kinase family signature 215 235 1.9E-50 T 06-07-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 BWK49_RS10005 54cdb66f212ef6ad2bdf601275bc9452 367 PRINTS PR00474 Glutamate 5-kinase family signature 123 144 1.9E-50 T 06-07-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 BWK49_RS10005 54cdb66f212ef6ad2bdf601275bc9452 367 Gene3D G3DSA:3.40.1160.10 13 258 8.6E-53 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase BWK49_RS10005 54cdb66f212ef6ad2bdf601275bc9452 367 TIGRFAM TIGR01027 proB: glutamate 5-kinase 13 365 3.0E-130 T 06-07-2017 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 BWK49_RS10005 54cdb66f212ef6ad2bdf601275bc9452 367 Pfam PF00696 Amino acid kinase family 14 239 1.4E-34 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase BWK49_RS10005 54cdb66f212ef6ad2bdf601275bc9452 367 Hamap MF_00456 Glutamate 5-kinase [proB]. 12 261 33.367 T 06-07-2017 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 BWK49_RS10005 54cdb66f212ef6ad2bdf601275bc9452 367 PIRSF PIRSF000729 7 367 3.2E-115 T 06-07-2017 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 BWK49_RS10005 54cdb66f212ef6ad2bdf601275bc9452 367 ProSitePatterns PS00902 Glutamate 5-kinase signature. 213 230 - T 06-07-2017 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 BWK49_RS10005 54cdb66f212ef6ad2bdf601275bc9452 367 Pfam PF01472 PUA domain 280 350 3.9E-14 T 06-07-2017 IPR002478 PUA domain GO:0003723 BWK49_RS10005 54cdb66f212ef6ad2bdf601275bc9452 367 Gene3D G3DSA:2.30.130.10 278 365 5.7E-20 T 06-07-2017 IPR015947 PUA-like domain BWK49_RS26330 6f6ae0f636b205b31090128b7fe088cc 215 Pfam PF11259 Protein of unknown function (DUF3060) 152 208 4.2E-23 T 06-07-2017 IPR021417 Protein of unknown function DUF3060 BWK49_RS02580 afb8c085e39c020a2ffd8a455e8a485d 226 SUPERFAMILY SSF53335 8 187 1.99E-34 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS02580 afb8c085e39c020a2ffd8a455e8a485d 226 Gene3D G3DSA:3.40.50.150 24 185 7.7E-36 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS02580 afb8c085e39c020a2ffd8a455e8a485d 226 Pfam PF13649 Methyltransferase domain 47 141 1.6E-16 T 06-07-2017 BWK49_RS08810 ca20d176d5840fc74042addfdd8669a1 613 Gene3D G3DSA:3.40.50.300 4 208 1.5E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS08810 ca20d176d5840fc74042addfdd8669a1 613 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 58 73 - T 06-07-2017 IPR031157 Tr-type G domain, conserved site BWK49_RS08810 ca20d176d5840fc74042addfdd8669a1 613 Hamap MF_00062 Sulfate adenylyltransferase subunit 1 [cysN]. 1 443 48.181 T 06-07-2017 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 BWK49_RS08810 ca20d176d5840fc74042addfdd8669a1 613 TIGRFAM TIGR02034 CysN: sulfate adenylyltransferase, large subunit 5 414 9.5E-174 T 06-07-2017 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 BWK49_RS08810 ca20d176d5840fc74042addfdd8669a1 613 SUPERFAMILY SSF52540 440 611 2.44E-36 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS08810 ca20d176d5840fc74042addfdd8669a1 613 Gene3D G3DSA:2.40.30.10 220 306 2.4E-15 T 06-07-2017 BWK49_RS08810 ca20d176d5840fc74042addfdd8669a1 613 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 440 613 37.041 T 06-07-2017 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 BWK49_RS08810 ca20d176d5840fc74042addfdd8669a1 613 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 438 608 3.6E-62 T 06-07-2017 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 BWK49_RS08810 ca20d176d5840fc74042addfdd8669a1 613 SUPERFAMILY SSF50447 220 308 1.46E-18 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain BWK49_RS08810 ca20d176d5840fc74042addfdd8669a1 613 SUPERFAMILY SSF50465 311 415 2.73E-31 T 06-07-2017 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal BWK49_RS08810 ca20d176d5840fc74042addfdd8669a1 613 Pfam PF00009 Elongation factor Tu GTP binding domain 5 188 1.3E-39 T 06-07-2017 BWK49_RS08810 ca20d176d5840fc74042addfdd8669a1 613 Gene3D G3DSA:3.40.50.300 437 613 2.3E-71 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS08810 ca20d176d5840fc74042addfdd8669a1 613 Gene3D G3DSA:2.40.30.10 309 415 1.5E-10 T 06-07-2017 BWK49_RS08810 ca20d176d5840fc74042addfdd8669a1 613 PRINTS PR00315 GTP-binding elongation factor signature 138 147 6.6E-11 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 BWK49_RS08810 ca20d176d5840fc74042addfdd8669a1 613 PRINTS PR00315 GTP-binding elongation factor signature 6 19 6.6E-11 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 BWK49_RS08810 ca20d176d5840fc74042addfdd8669a1 613 PRINTS PR00315 GTP-binding elongation factor signature 65 73 6.6E-11 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 BWK49_RS08810 ca20d176d5840fc74042addfdd8669a1 613 PRINTS PR00315 GTP-binding elongation factor signature 85 95 6.6E-11 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 BWK49_RS08810 ca20d176d5840fc74042addfdd8669a1 613 PRINTS PR00315 GTP-binding elongation factor signature 101 112 6.6E-11 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 BWK49_RS08810 ca20d176d5840fc74042addfdd8669a1 613 SUPERFAMILY SSF52540 4 210 3.69E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS08810 ca20d176d5840fc74042addfdd8669a1 613 Pfam PF01583 Adenylylsulphate kinase 441 593 1.1E-66 T 06-07-2017 BWK49_RS23830 5f0bd181bbc29d69c96c61d8df768381 538 SUPERFAMILY SSF48592 6 133 9.92E-70 T 06-07-2017 BWK49_RS23830 5f0bd181bbc29d69c96c61d8df768381 538 SUPERFAMILY SSF48592 404 520 9.92E-70 T 06-07-2017 BWK49_RS23830 5f0bd181bbc29d69c96c61d8df768381 538 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 525 1.6E-219 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 BWK49_RS23830 5f0bd181bbc29d69c96c61d8df768381 538 Gene3D G3DSA:1.10.560.10 6 184 1.0E-40 T 06-07-2017 IPR027413 GroEL-like equatorial domain BWK49_RS23830 5f0bd181bbc29d69c96c61d8df768381 538 Gene3D G3DSA:1.10.560.10 367 517 2.3E-38 T 06-07-2017 IPR027413 GroEL-like equatorial domain BWK49_RS23830 5f0bd181bbc29d69c96c61d8df768381 538 Gene3D G3DSA:3.50.7.10 185 366 7.6E-84 T 06-07-2017 IPR027409 GroEL-like apical domain BWK49_RS23830 5f0bd181bbc29d69c96c61d8df768381 538 SUPERFAMILY SSF54849 136 202 2.75E-21 T 06-07-2017 BWK49_RS23830 5f0bd181bbc29d69c96c61d8df768381 538 PRINTS PR00298 60kDa chaperonin signature 266 289 1.2E-67 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 BWK49_RS23830 5f0bd181bbc29d69c96c61d8df768381 538 PRINTS PR00298 60kDa chaperonin signature 396 417 1.2E-67 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 BWK49_RS23830 5f0bd181bbc29d69c96c61d8df768381 538 PRINTS PR00298 60kDa chaperonin signature 82 109 1.2E-67 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 BWK49_RS23830 5f0bd181bbc29d69c96c61d8df768381 538 PRINTS PR00298 60kDa chaperonin signature 26 52 1.2E-67 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 BWK49_RS23830 5f0bd181bbc29d69c96c61d8df768381 538 PRINTS PR00298 60kDa chaperonin signature 348 373 1.2E-67 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 BWK49_RS23830 5f0bd181bbc29d69c96c61d8df768381 538 ProSitePatterns PS00296 Chaperonins cpn60 signature. 403 414 - T 06-07-2017 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020 BWK49_RS23830 5f0bd181bbc29d69c96c61d8df768381 538 Hamap MF_00600 60 kDa chaperonin [groL]. 1 535 38.688 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 BWK49_RS23830 5f0bd181bbc29d69c96c61d8df768381 538 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 524 2.9E-89 T 06-07-2017 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 BWK49_RS23830 5f0bd181bbc29d69c96c61d8df768381 538 SUPERFAMILY SSF52029 183 374 9.27E-74 T 06-07-2017 IPR027409 GroEL-like apical domain BWK49_RS14355 16c7c8af5805ee4621d1c8b6e661a2de 416 SUPERFAMILY SSF53756 2 407 5.5E-81 T 06-07-2017 BWK49_RS14355 16c7c8af5805ee4621d1c8b6e661a2de 416 Gene3D G3DSA:3.40.50.2000 198 383 7.3E-32 T 06-07-2017 BWK49_RS14355 16c7c8af5805ee4621d1c8b6e661a2de 416 Pfam PF00534 Glycosyl transferases group 1 221 384 5.9E-29 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 BWK49_RS14355 16c7c8af5805ee4621d1c8b6e661a2de 416 Pfam PF13579 Glycosyl transferase 4-like domain 15 212 5.0E-25 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 BWK49_RS05935 14a22fc760e0c6baaf65b63ae1dd6c07 273 PRINTS PR00412 Epoxide hydrolase signature 52 67 7.0E-7 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS05935 14a22fc760e0c6baaf65b63ae1dd6c07 273 PRINTS PR00412 Epoxide hydrolase signature 214 230 7.0E-7 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS05935 14a22fc760e0c6baaf65b63ae1dd6c07 273 PRINTS PR00412 Epoxide hydrolase signature 247 269 7.0E-7 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS05935 14a22fc760e0c6baaf65b63ae1dd6c07 273 Gene3D G3DSA:3.40.50.1820 3 272 2.3E-48 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS05935 14a22fc760e0c6baaf65b63ae1dd6c07 273 PRINTS PR00111 Alpha/beta hydrolase fold signature 52 67 1.6E-10 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS05935 14a22fc760e0c6baaf65b63ae1dd6c07 273 PRINTS PR00111 Alpha/beta hydrolase fold signature 97 110 1.6E-10 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS05935 14a22fc760e0c6baaf65b63ae1dd6c07 273 PRINTS PR00111 Alpha/beta hydrolase fold signature 216 230 1.6E-10 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS05935 14a22fc760e0c6baaf65b63ae1dd6c07 273 SUPERFAMILY SSF53474 2 271 1.37E-47 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS05935 14a22fc760e0c6baaf65b63ae1dd6c07 273 Pfam PF12697 Alpha/beta hydrolase family 26 262 3.4E-22 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS15905 0a5c1b032dfdd83b958b26cbb1697f20 374 Gene3D G3DSA:3.50.50.60 243 309 2.0E-13 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS15905 0a5c1b032dfdd83b958b26cbb1697f20 374 Gene3D G3DSA:3.50.50.60 3 109 2.0E-13 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS15905 0a5c1b032dfdd83b958b26cbb1697f20 374 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 1.0E-11 T 06-07-2017 BWK49_RS15905 0a5c1b032dfdd83b958b26cbb1697f20 374 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 142 160 1.0E-11 T 06-07-2017 BWK49_RS15905 0a5c1b032dfdd83b958b26cbb1697f20 374 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 233 249 1.0E-11 T 06-07-2017 BWK49_RS15905 0a5c1b032dfdd83b958b26cbb1697f20 374 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 260 282 1.0E-11 T 06-07-2017 BWK49_RS15905 0a5c1b032dfdd83b958b26cbb1697f20 374 Gene3D G3DSA:3.50.50.60 110 242 1.8E-8 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS15905 0a5c1b032dfdd83b958b26cbb1697f20 374 SUPERFAMILY SSF51905 236 297 2.16E-17 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS15905 0a5c1b032dfdd83b958b26cbb1697f20 374 SUPERFAMILY SSF51905 3 151 2.16E-17 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS15905 0a5c1b032dfdd83b958b26cbb1697f20 374 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 283 3.7E-18 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS15905 0a5c1b032dfdd83b958b26cbb1697f20 374 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 5 27 2.6E-10 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 BWK49_RS15905 0a5c1b032dfdd83b958b26cbb1697f20 374 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 270 288 2.6E-10 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 BWK49_RS15905 0a5c1b032dfdd83b958b26cbb1697f20 374 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 138 162 2.6E-10 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 BWK49_RS15905 0a5c1b032dfdd83b958b26cbb1697f20 374 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 102 110 2.6E-10 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 BWK49_RS15905 0a5c1b032dfdd83b958b26cbb1697f20 374 SUPERFAMILY SSF51905 142 295 6.48E-17 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS23940 653e7eed734b8b5827df94d0f9854a56 147 Gene3D G3DSA:3.90.1180.10 3 141 6.9E-59 T 06-07-2017 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 BWK49_RS23940 653e7eed734b8b5827df94d0f9854a56 147 SUPERFAMILY SSF52161 5 144 1.57E-55 T 06-07-2017 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 BWK49_RS23940 653e7eed734b8b5827df94d0f9854a56 147 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 5 141 4.6E-60 T 06-07-2017 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS23940 653e7eed734b8b5827df94d0f9854a56 147 PIRSF PIRSF002181 3 147 4.8E-47 T 06-07-2017 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 BWK49_RS23940 653e7eed734b8b5827df94d0f9854a56 147 Pfam PF00572 Ribosomal protein L13 15 137 1.3E-53 T 06-07-2017 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 BWK49_RS23940 653e7eed734b8b5827df94d0f9854a56 147 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 15 143 27.021 T 06-07-2017 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 BWK49_RS27580 fab41beac286edd177492c6b0eceb8fc 368 Pfam PF00487 Fatty acid desaturase 63 328 5.8E-33 T 06-07-2017 IPR005804 Fatty acid desaturase domain GO:0006629 BWK49_RS08275 d9d5f9de44aad9e93655f88d0b3baae6 644 Gene3D G3DSA:3.90.76.10 118 200 5.1E-10 T 06-07-2017 BWK49_RS08275 d9d5f9de44aad9e93655f88d0b3baae6 644 Gene3D G3DSA:3.10.105.10 329 505 2.0E-18 T 06-07-2017 BWK49_RS08275 d9d5f9de44aad9e93655f88d0b3baae6 644 Gene3D G3DSA:3.10.105.10 559 608 2.0E-18 T 06-07-2017 BWK49_RS08275 d9d5f9de44aad9e93655f88d0b3baae6 644 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 120 491 5.0E-36 T 06-07-2017 IPR000914 Solute-binding protein family 5 domain BWK49_RS08275 d9d5f9de44aad9e93655f88d0b3baae6 644 SUPERFAMILY SSF53850 66 513 2.85E-56 T 06-07-2017 BWK49_RS08275 d9d5f9de44aad9e93655f88d0b3baae6 644 SUPERFAMILY SSF53850 560 625 2.85E-56 T 06-07-2017 BWK49_RS08275 d9d5f9de44aad9e93655f88d0b3baae6 644 Gene3D G3DSA:3.40.190.10 201 328 3.8E-17 T 06-07-2017 BWK49_RS12165 7b67ea7baba7b133f4f1ac4fc4ed807e 379 SUPERFAMILY SSF53756 1 362 1.3E-61 T 06-07-2017 BWK49_RS12165 7b67ea7baba7b133f4f1ac4fc4ed807e 379 Gene3D G3DSA:3.40.50.2000 168 346 6.8E-25 T 06-07-2017 BWK49_RS12165 7b67ea7baba7b133f4f1ac4fc4ed807e 379 Pfam PF00534 Glycosyl transferases group 1 198 346 1.2E-23 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 BWK49_RS12165 7b67ea7baba7b133f4f1ac4fc4ed807e 379 Pfam PF13439 Glycosyltransferase Family 4 15 179 4.3E-10 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 BWK49_RS18385 964df94654aebb4b4a1df2163d0375b0 312 SUPERFAMILY SSF53328 2 206 9.42E-55 T 06-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 BWK49_RS18385 964df94654aebb4b4a1df2163d0375b0 312 Pfam PF02911 Formyl transferase, C-terminal domain 204 303 1.0E-21 T 06-07-2017 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 BWK49_RS18385 964df94654aebb4b4a1df2163d0375b0 312 SUPERFAMILY SSF50486 205 309 1.77E-25 T 06-07-2017 IPR011034 Formyl transferase, C-terminal-like GO:0003824 BWK49_RS18385 964df94654aebb4b4a1df2163d0375b0 312 Pfam PF00551 Formyl transferase 15 178 3.5E-29 T 06-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 BWK49_RS18385 964df94654aebb4b4a1df2163d0375b0 312 Gene3D G3DSA:3.10.25.10 208 308 1.3E-26 T 06-07-2017 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 BWK49_RS18385 964df94654aebb4b4a1df2163d0375b0 312 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 1 306 30.281 T 06-07-2017 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 BWK49_RS18385 964df94654aebb4b4a1df2163d0375b0 312 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 2 304 2.1E-69 T 06-07-2017 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 BWK49_RS18385 964df94654aebb4b4a1df2163d0375b0 312 Gene3D G3DSA:3.40.50.170 2 206 3.3E-56 T 06-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 BWK49_RS14810 140193f52719c932aef8cdee5e3a1467 249 SUPERFAMILY SSF52096 3 246 1.64E-62 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS14810 140193f52719c932aef8cdee5e3a1467 249 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 234 1.3E-42 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 BWK49_RS14810 140193f52719c932aef8cdee5e3a1467 249 Gene3D G3DSA:3.90.226.10 3 246 1.0E-63 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS24340 e7ff22ade9bdf36ce951a86affffc586 219 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 66 2.3E-12 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS24340 e7ff22ade9bdf36ce951a86affffc586 219 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 5.8E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS24340 e7ff22ade9bdf36ce951a86affffc586 219 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 5.8E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS24340 e7ff22ade9bdf36ce951a86affffc586 219 Gene3D G3DSA:1.10.357.10 7 203 1.4E-27 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS24340 e7ff22ade9bdf36ce951a86affffc586 219 SUPERFAMILY SSF46689 10 70 1.1E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS18730 bbbdb3dbb5e88ae3575e7edb78ad3bd3 526 Gene3D G3DSA:3.60.21.10 159 524 4.3E-70 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like BWK49_RS18730 bbbdb3dbb5e88ae3575e7edb78ad3bd3 526 Gene3D G3DSA:2.60.40.380 63 155 1.7E-13 T 06-07-2017 IPR015914 Purple acid phosphatase, N-terminal GO:0003993|GO:0046872 BWK49_RS18730 bbbdb3dbb5e88ae3575e7edb78ad3bd3 526 SUPERFAMILY SSF49363 47 155 6.15E-21 T 06-07-2017 IPR008963 Purple acid phosphatase-like, N-terminal GO:0003993|GO:0046872 BWK49_RS18730 bbbdb3dbb5e88ae3575e7edb78ad3bd3 526 Pfam PF16656 Purple acid Phosphatase, N-terminal domain 62 144 1.2E-15 T 06-07-2017 IPR015914 Purple acid phosphatase, N-terminal GO:0003993|GO:0046872 BWK49_RS18730 bbbdb3dbb5e88ae3575e7edb78ad3bd3 526 SUPERFAMILY SSF56300 159 519 5.62E-45 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like BWK49_RS18730 bbbdb3dbb5e88ae3575e7edb78ad3bd3 526 Pfam PF00149 Calcineurin-like phosphoesterase 203 384 1.9E-13 T 06-07-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 BWK49_RS17735 4b7a9d388f00ff356f9b670d522b4fab 428 Gene3D G3DSA:3.40.50.2000 1 248 2.7E-62 T 06-07-2017 BWK49_RS17735 4b7a9d388f00ff356f9b670d522b4fab 428 Gene3D G3DSA:3.40.50.2000 249 395 3.4E-53 T 06-07-2017 BWK49_RS17735 4b7a9d388f00ff356f9b670d522b4fab 428 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 4 80 1.1E-7 T 06-07-2017 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 BWK49_RS17735 4b7a9d388f00ff356f9b670d522b4fab 428 SUPERFAMILY SSF53756 1 416 6.91E-94 T 06-07-2017 BWK49_RS13940 eaca3c25940e8149f25cb62ccd51cd17 274 Gene3D G3DSA:3.10.129.10 7 111 1.2E-33 T 06-07-2017 IPR029069 HotDog domain BWK49_RS13940 eaca3c25940e8149f25cb62ccd51cd17 274 SUPERFAMILY SSF54637 7 112 2.42E-32 T 06-07-2017 IPR029069 HotDog domain BWK49_RS13940 eaca3c25940e8149f25cb62ccd51cd17 274 Gene3D G3DSA:3.10.129.10 128 269 2.7E-25 T 06-07-2017 IPR029069 HotDog domain BWK49_RS13940 eaca3c25940e8149f25cb62ccd51cd17 274 Pfam PF13622 Thioesterase-like superfamily 32 269 3.6E-39 T 06-07-2017 BWK49_RS13940 eaca3c25940e8149f25cb62ccd51cd17 274 SUPERFAMILY SSF54637 119 270 7.92E-30 T 06-07-2017 IPR029069 HotDog domain BWK49_RS08560 8f7527d0267ee3435434850b65a17c14 435 SUPERFAMILY SSF50346 10 89 2.47E-7 T 06-07-2017 IPR011033 PRC-barrel-like BWK49_RS08560 8f7527d0267ee3435434850b65a17c14 435 Gene3D G3DSA:3.10.580.10 286 411 2.7E-20 T 06-07-2017 BWK49_RS08560 8f7527d0267ee3435434850b65a17c14 435 SMART SM00924 184 287 2.8E-32 T 06-07-2017 IPR006668 Magnesium transporter, MgtE intracellular domain BWK49_RS08560 8f7527d0267ee3435434850b65a17c14 435 SUPERFAMILY SSF54631 286 413 3.23E-23 T 06-07-2017 BWK49_RS08560 8f7527d0267ee3435434850b65a17c14 435 Gene3D G3DSA:1.25.60.10 168 281 1.7E-36 T 06-07-2017 BWK49_RS08560 8f7527d0267ee3435434850b65a17c14 435 Pfam PF00571 CBS domain 356 411 1.4E-5 T 06-07-2017 IPR000644 CBS domain BWK49_RS08560 8f7527d0267ee3435434850b65a17c14 435 Pfam PF00571 CBS domain 288 350 6.3E-5 T 06-07-2017 IPR000644 CBS domain BWK49_RS08560 8f7527d0267ee3435434850b65a17c14 435 Pfam PF03448 MgtE intracellular N domain 185 285 8.0E-24 T 06-07-2017 IPR006668 Magnesium transporter, MgtE intracellular domain BWK49_RS08560 8f7527d0267ee3435434850b65a17c14 435 SUPERFAMILY SSF158791 169 282 6.28E-28 T 06-07-2017 BWK49_RS16480 6999c43d468bc4e08f7f0c731d772153 427 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 39 57 3.9E-8 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 BWK49_RS16480 6999c43d468bc4e08f7f0c731d772153 427 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 59 71 3.9E-8 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 BWK49_RS16480 6999c43d468bc4e08f7f0c731d772153 427 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 278 297 3.9E-8 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 BWK49_RS16480 6999c43d468bc4e08f7f0c731d772153 427 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 160 173 3.9E-8 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 BWK49_RS16480 6999c43d468bc4e08f7f0c731d772153 427 Gene3D G3DSA:3.20.20.10 16 207 3.4E-45 T 06-07-2017 IPR029066 PLP-binding barrel BWK49_RS16480 6999c43d468bc4e08f7f0c731d772153 427 SUPERFAMILY SSF50621 270 416 3.4E-15 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 BWK49_RS16480 6999c43d468bc4e08f7f0c731d772153 427 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 30 214 4.0E-22 T 06-07-2017 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 BWK49_RS16480 6999c43d468bc4e08f7f0c731d772153 427 SUPERFAMILY SSF51419 17 215 4.07E-42 T 06-07-2017 IPR029066 PLP-binding barrel BWK49_RS16480 6999c43d468bc4e08f7f0c731d772153 427 SUPERFAMILY SSF51419 258 291 4.07E-42 T 06-07-2017 IPR029066 PLP-binding barrel BWK49_RS16480 6999c43d468bc4e08f7f0c731d772153 427 Gene3D G3DSA:2.40.37.10 257 413 5.3E-22 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 BWK49_RS16480 6999c43d468bc4e08f7f0c731d772153 427 Gene3D G3DSA:2.40.37.10 208 219 5.3E-22 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 BWK49_RS26670 7eb157a1ec7c815cddb898c4c95c5aa6 248 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 53 61 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 BWK49_RS26670 7eb157a1ec7c815cddb898c4c95c5aa6 248 Gene3D G3DSA:3.10.20.30 4 95 2.9E-30 T 06-07-2017 IPR012675 Beta-grasp domain BWK49_RS26670 7eb157a1ec7c815cddb898c4c95c5aa6 248 Pfam PF13183 4Fe-4S dicluster domain 140 216 3.6E-15 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain BWK49_RS26670 7eb157a1ec7c815cddb898c4c95c5aa6 248 SUPERFAMILY SSF54292 3 103 2.23E-24 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 BWK49_RS26670 7eb157a1ec7c815cddb898c4c95c5aa6 248 SUPERFAMILY SSF46548 124 228 3.31E-19 T 06-07-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 BWK49_RS26670 7eb157a1ec7c815cddb898c4c95c5aa6 248 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 13 219 3.7E-44 T 06-07-2017 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 BWK49_RS26670 7eb157a1ec7c815cddb898c4c95c5aa6 248 Gene3D G3DSA:1.10.1060.10 96 238 1.4E-20 T 06-07-2017 BWK49_RS26670 7eb157a1ec7c815cddb898c4c95c5aa6 248 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 6 105 9.3E-28 T 06-07-2017 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 BWK49_RS02290 06b66b1b3a24d871c7912e21fdfadae6 375 ProSitePatterns PS00480 Citrate synthase signature. 263 275 - T 06-07-2017 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 BWK49_RS02290 06b66b1b3a24d871c7912e21fdfadae6 375 PIRSF PIRSF001369 6 375 2.0E-119 T 06-07-2017 IPR024176 Citrate synthase, bacterial-type BWK49_RS02290 06b66b1b3a24d871c7912e21fdfadae6 375 SUPERFAMILY SSF48256 11 372 1.96E-122 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 BWK49_RS02290 06b66b1b3a24d871c7912e21fdfadae6 375 PRINTS PR00143 Citrate synthase signature 333 347 5.0E-36 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 BWK49_RS02290 06b66b1b3a24d871c7912e21fdfadae6 375 PRINTS PR00143 Citrate synthase signature 132 145 5.0E-36 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 BWK49_RS02290 06b66b1b3a24d871c7912e21fdfadae6 375 PRINTS PR00143 Citrate synthase signature 181 196 5.0E-36 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 BWK49_RS02290 06b66b1b3a24d871c7912e21fdfadae6 375 PRINTS PR00143 Citrate synthase signature 203 231 5.0E-36 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 BWK49_RS02290 06b66b1b3a24d871c7912e21fdfadae6 375 PRINTS PR00143 Citrate synthase signature 256 276 5.0E-36 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 BWK49_RS02290 06b66b1b3a24d871c7912e21fdfadae6 375 PRINTS PR00143 Citrate synthase signature 313 329 5.0E-36 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 BWK49_RS02290 06b66b1b3a24d871c7912e21fdfadae6 375 Gene3D G3DSA:1.10.580.10 22 242 9.1E-79 T 06-07-2017 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 BWK49_RS02290 06b66b1b3a24d871c7912e21fdfadae6 375 TIGRFAM TIGR01800 cit_synth_II: 2-methylcitrate synthase/citrate synthase II 13 372 2.2E-141 T 06-07-2017 IPR011278 2-methylcitrate synthase/citrate synthase type I GO:0005737|GO:0046912 BWK49_RS02290 06b66b1b3a24d871c7912e21fdfadae6 375 Pfam PF00285 Citrate synthase, C-terminal domain 14 362 4.4E-115 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 BWK49_RS02290 06b66b1b3a24d871c7912e21fdfadae6 375 Gene3D G3DSA:1.10.230.10 243 327 3.2E-28 T 06-07-2017 IPR016143 Citrate synthase-like, small alpha subdomain Reactome: R-HSA-163765|Reactome: R-HSA-75105 BWK49_RS10820 9961cbfa6b8a429c87d5850bf4ceef9e 267 SUPERFAMILY SSF51735 7 263 3.1E-62 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS10820 9961cbfa6b8a429c87d5850bf4ceef9e 267 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 215 0.0023 T 06-07-2017 BWK49_RS10820 9961cbfa6b8a429c87d5850bf4ceef9e 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 6.7E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS10820 9961cbfa6b8a429c87d5850bf4ceef9e 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 6.7E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS10820 9961cbfa6b8a429c87d5850bf4ceef9e 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 228 248 6.7E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS10820 9961cbfa6b8a429c87d5850bf4ceef9e 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 6.7E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS10820 9961cbfa6b8a429c87d5850bf4ceef9e 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 6.7E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS10820 9961cbfa6b8a429c87d5850bf4ceef9e 267 Gene3D G3DSA:3.40.50.720 2 263 3.1E-63 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS10820 9961cbfa6b8a429c87d5850bf4ceef9e 267 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS10820 9961cbfa6b8a429c87d5850bf4ceef9e 267 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 263 4.4E-46 T 06-07-2017 BWK49_RS10305 1c90bd87b1cd75b7e304b45755f127c8 305 Pfam PF07859 alpha/beta hydrolase fold 72 270 1.0E-40 T 06-07-2017 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 BWK49_RS10305 1c90bd87b1cd75b7e304b45755f127c8 305 Gene3D G3DSA:3.40.50.1820 56 291 4.3E-52 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS10305 1c90bd87b1cd75b7e304b45755f127c8 305 SUPERFAMILY SSF53474 3 292 2.7E-46 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS24640 dc1483fb119e042cb994ebba691f5bb6 237 Gene3D G3DSA:3.60.15.10 22 220 4.9E-55 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS24640 dc1483fb119e042cb994ebba691f5bb6 237 Pfam PF00753 Metallo-beta-lactamase superfamily 30 203 2.0E-16 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS24640 dc1483fb119e042cb994ebba691f5bb6 237 SMART SM00849 28 203 1.4E-33 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS24640 dc1483fb119e042cb994ebba691f5bb6 237 SUPERFAMILY SSF56281 27 224 1.23E-46 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS17020 5f810dbdbc1e7be430eb648580307e13 201 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 1 170 29.281 T 06-07-2017 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 BWK49_RS17020 5f810dbdbc1e7be430eb648580307e13 201 SUPERFAMILY SSF55200 85 168 2.62E-29 T 06-07-2017 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 BWK49_RS17020 5f810dbdbc1e7be430eb648580307e13 201 Gene3D G3DSA:3.10.20.80 3 77 1.9E-35 T 06-07-2017 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 BWK49_RS17020 5f810dbdbc1e7be430eb648580307e13 201 ProSitePatterns PS00938 Initiation factor 3 signature. 58 71 - T 06-07-2017 IPR019813 Translation initiation factor 3, conserved site GO:0003743|GO:0006413 BWK49_RS17020 5f810dbdbc1e7be430eb648580307e13 201 SUPERFAMILY SSF54364 5 78 1.44E-28 T 06-07-2017 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 BWK49_RS17020 5f810dbdbc1e7be430eb648580307e13 201 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 84 167 2.3E-32 T 06-07-2017 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 BWK49_RS17020 5f810dbdbc1e7be430eb648580307e13 201 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 7 168 1.9E-60 T 06-07-2017 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 BWK49_RS17020 5f810dbdbc1e7be430eb648580307e13 201 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 7 75 1.8E-30 T 06-07-2017 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 BWK49_RS17020 5f810dbdbc1e7be430eb648580307e13 201 Gene3D G3DSA:3.30.110.10 79 169 8.6E-36 T 06-07-2017 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 BWK49_RS12895 6a7f5f55a9cd0f3b0d182d7a98ccb8c4 408 Pfam PF00355 Rieske [2Fe-2S] domain 322 379 5.1E-9 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS12895 6a7f5f55a9cd0f3b0d182d7a98ccb8c4 408 SUPERFAMILY SSF50022 240 400 2.12E-23 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS12895 6a7f5f55a9cd0f3b0d182d7a98ccb8c4 408 Gene3D G3DSA:2.102.10.10 249 405 3.7E-39 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS12895 6a7f5f55a9cd0f3b0d182d7a98ccb8c4 408 Gene3D G3DSA:2.102.10.10 187 212 3.7E-39 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS15135 773de3e6ceefb0374b9c47ec55da2de9 497 Gene3D G3DSA:3.90.700.10 308 418 2.6E-24 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 BWK49_RS15135 773de3e6ceefb0374b9c47ec55da2de9 497 SUPERFAMILY SSF56425 305 422 2.44E-26 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 BWK49_RS15135 773de3e6ceefb0374b9c47ec55da2de9 497 Gene3D G3DSA:3.50.50.60 11 290 1.6E-67 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS15135 773de3e6ceefb0374b9c47ec55da2de9 497 Gene3D G3DSA:3.50.50.60 430 493 1.6E-67 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS15135 773de3e6ceefb0374b9c47ec55da2de9 497 SUPERFAMILY SSF51905 433 494 1.65E-41 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS15135 773de3e6ceefb0374b9c47ec55da2de9 497 SUPERFAMILY SSF51905 14 133 1.65E-41 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS15135 773de3e6ceefb0374b9c47ec55da2de9 497 SUPERFAMILY SSF51905 161 308 1.65E-41 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS15135 773de3e6ceefb0374b9c47ec55da2de9 497 Pfam PF00890 FAD binding domain 22 461 5.5E-50 T 06-07-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 BWK49_RS07725 cc4372a5c9c5da8a82b232b46a81732e 468 Pfam PF00571 CBS domain 330 395 4.0E-7 T 06-07-2017 IPR000644 CBS domain BWK49_RS07725 cc4372a5c9c5da8a82b232b46a81732e 468 Pfam PF00571 CBS domain 406 458 9.3E-7 T 06-07-2017 IPR000644 CBS domain BWK49_RS07725 cc4372a5c9c5da8a82b232b46a81732e 468 SUPERFAMILY SSF53686 1 317 1.03E-90 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme BWK49_RS07725 cc4372a5c9c5da8a82b232b46a81732e 468 Gene3D G3DSA:3.40.50.1100 38 138 4.3E-36 T 06-07-2017 BWK49_RS07725 cc4372a5c9c5da8a82b232b46a81732e 468 SUPERFAMILY SSF54631 329 459 7.71E-19 T 06-07-2017 BWK49_RS07725 cc4372a5c9c5da8a82b232b46a81732e 468 Gene3D G3DSA:3.10.580.10 331 459 7.3E-21 T 06-07-2017 BWK49_RS07725 cc4372a5c9c5da8a82b232b46a81732e 468 Gene3D G3DSA:3.40.50.1100 139 310 1.0E-65 T 06-07-2017 BWK49_RS07725 cc4372a5c9c5da8a82b232b46a81732e 468 TIGRFAM TIGR01137 cysta_beta: cystathionine beta-synthase 3 458 5.7E-208 T 06-07-2017 IPR005857 Cystathionine beta-synthase GO:0004122|GO:0005737|GO:0019343 KEGG: 00260+4.2.1.22|KEGG: 00270+4.2.1.22|MetaCyc: PWY-801 BWK49_RS07725 cc4372a5c9c5da8a82b232b46a81732e 468 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 8 296 3.1E-63 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme BWK49_RS07725 cc4372a5c9c5da8a82b232b46a81732e 468 SMART SM00116 343 396 3.4E-4 T 06-07-2017 IPR000644 CBS domain BWK49_RS07725 cc4372a5c9c5da8a82b232b46a81732e 468 SMART SM00116 413 458 1.3 T 06-07-2017 IPR000644 CBS domain BWK49_RS20875 64a8c3647e70685ada9609add081a8db 233 SUPERFAMILY SSF55781 62 233 3.34E-36 T 06-07-2017 IPR029016 GAF domain-like BWK49_RS20875 64a8c3647e70685ada9609add081a8db 233 SMART SM00346 7 92 7.0E-26 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 BWK49_RS20875 64a8c3647e70685ada9609add081a8db 233 Pfam PF09339 IclR helix-turn-helix domain 10 58 1.3E-10 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 BWK49_RS20875 64a8c3647e70685ada9609add081a8db 233 Gene3D G3DSA:3.30.450.40 73 233 2.3E-41 T 06-07-2017 IPR029016 GAF domain-like BWK49_RS20875 64a8c3647e70685ada9609add081a8db 233 SUPERFAMILY SSF46785 8 75 1.09E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS20875 64a8c3647e70685ada9609add081a8db 233 Pfam PF01614 Bacterial transcriptional regulator 124 228 2.4E-18 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal BWK49_RS20875 64a8c3647e70685ada9609add081a8db 233 Gene3D G3DSA:1.10.10.10 5 67 1.0E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS21280 2edb812b791859ecd1dbb887d0a845d8 581 Gene3D G3DSA:1.20.210.10 25 551 1.0E-193 T 06-07-2017 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 BWK49_RS21280 2edb812b791859ecd1dbb887d0a845d8 581 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 260 314 - T 06-07-2017 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 BWK49_RS21280 2edb812b791859ecd1dbb887d0a845d8 581 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 32 535 1.0E-215 T 06-07-2017 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005507|GO:0005886|GO:0006810|GO:0022900|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 BWK49_RS21280 2edb812b791859ecd1dbb887d0a845d8 581 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 40 483 5.9E-150 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 BWK49_RS21280 2edb812b791859ecd1dbb887d0a845d8 581 PRINTS PR01165 Cytochrome c oxidase subunit I signature 30 55 4.5E-96 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 BWK49_RS21280 2edb812b791859ecd1dbb887d0a845d8 581 PRINTS PR01165 Cytochrome c oxidase subunit I signature 208 227 4.5E-96 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 BWK49_RS21280 2edb812b791859ecd1dbb887d0a845d8 581 PRINTS PR01165 Cytochrome c oxidase subunit I signature 361 379 4.5E-96 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 BWK49_RS21280 2edb812b791859ecd1dbb887d0a845d8 581 PRINTS PR01165 Cytochrome c oxidase subunit I signature 439 460 4.5E-96 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 BWK49_RS21280 2edb812b791859ecd1dbb887d0a845d8 581 PRINTS PR01165 Cytochrome c oxidase subunit I signature 389 408 4.5E-96 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 BWK49_RS21280 2edb812b791859ecd1dbb887d0a845d8 581 PRINTS PR01165 Cytochrome c oxidase subunit I signature 258 279 4.5E-96 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 BWK49_RS21280 2edb812b791859ecd1dbb887d0a845d8 581 PRINTS PR01165 Cytochrome c oxidase subunit I signature 326 347 4.5E-96 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 BWK49_RS21280 2edb812b791859ecd1dbb887d0a845d8 581 PRINTS PR01165 Cytochrome c oxidase subunit I signature 179 197 4.5E-96 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 BWK49_RS21280 2edb812b791859ecd1dbb887d0a845d8 581 PRINTS PR01165 Cytochrome c oxidase subunit I signature 237 258 4.5E-96 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 BWK49_RS21280 2edb812b791859ecd1dbb887d0a845d8 581 PRINTS PR01165 Cytochrome c oxidase subunit I signature 304 319 4.5E-96 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 BWK49_RS21280 2edb812b791859ecd1dbb887d0a845d8 581 PRINTS PR01165 Cytochrome c oxidase subunit I signature 147 159 4.5E-96 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 BWK49_RS21280 2edb812b791859ecd1dbb887d0a845d8 581 PRINTS PR01165 Cytochrome c oxidase subunit I signature 77 100 4.5E-96 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 BWK49_RS21280 2edb812b791859ecd1dbb887d0a845d8 581 PRINTS PR01165 Cytochrome c oxidase subunit I signature 104 128 4.5E-96 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 BWK49_RS21280 2edb812b791859ecd1dbb887d0a845d8 581 SUPERFAMILY SSF81442 27 538 2.49E-178 T 06-07-2017 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 BWK49_RS07895 a583ecbd567e6f00cb635ed1f3b2a187 246 SUPERFAMILY SSF56112 34 240 5.54E-27 T 06-07-2017 IPR011009 Protein kinase-like domain BWK49_RS07895 a583ecbd567e6f00cb635ed1f3b2a187 246 Gene3D G3DSA:3.30.200.20 29 106 3.7E-9 T 06-07-2017 BWK49_RS07895 a583ecbd567e6f00cb635ed1f3b2a187 246 Gene3D G3DSA:3.90.1200.10 155 243 2.6E-20 T 06-07-2017 BWK49_RS07895 a583ecbd567e6f00cb635ed1f3b2a187 246 Pfam PF01636 Phosphotransferase enzyme family 151 239 6.4E-11 T 06-07-2017 IPR002575 Aminoglycoside phosphotransferase BWK49_RS03270 b7ee80a178442809b31ae19d0a9b773b 394 Gene3D G3DSA:1.10.540.10 6 113 1.4E-40 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS03270 b7ee80a178442809b31ae19d0a9b773b 394 Gene3D G3DSA:2.40.110.10 116 203 2.2E-28 T 06-07-2017 BWK49_RS03270 b7ee80a178442809b31ae19d0a9b773b 394 SUPERFAMILY SSF56645 13 208 7.98E-36 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS03270 b7ee80a178442809b31ae19d0a9b773b 394 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 23 97 6.9E-5 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS03270 b7ee80a178442809b31ae19d0a9b773b 394 PIRSF PIRSF016578 1 394 5.8E-146 T 06-07-2017 BWK49_RS03270 b7ee80a178442809b31ae19d0a9b773b 394 SUPERFAMILY SSF47203 230 379 1.1E-13 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS03270 b7ee80a178442809b31ae19d0a9b773b 394 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 240 372 5.0E-41 T 06-07-2017 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain BWK49_RS03270 b7ee80a178442809b31ae19d0a9b773b 394 Gene3D G3DSA:1.20.140.10 204 393 1.4E-50 T 06-07-2017 BWK49_RS09820 4edfe43fc2363809d83c6dc8555ebf70 558 SUPERFAMILY SSF52540 8 241 9.16E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS09820 4edfe43fc2363809d83c6dc8555ebf70 558 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 BWK49_RS09820 4edfe43fc2363809d83c6dc8555ebf70 558 ProSitePatterns PS00211 ABC transporters family signature. 443 457 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 BWK49_RS09820 4edfe43fc2363809d83c6dc8555ebf70 558 Pfam PF00005 ABC transporter 21 188 8.8E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 BWK49_RS09820 4edfe43fc2363809d83c6dc8555ebf70 558 Pfam PF00005 ABC transporter 338 471 2.8E-20 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 BWK49_RS09820 4edfe43fc2363809d83c6dc8555ebf70 558 SMART SM00382 30 233 8.4E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS09820 4edfe43fc2363809d83c6dc8555ebf70 558 SMART SM00382 346 516 1.3E-6 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS09820 4edfe43fc2363809d83c6dc8555ebf70 558 Pfam PF12848 ABC transporter 227 306 5.5E-14 T 06-07-2017 IPR032781 ABC-transporter extension domain BWK49_RS09820 4edfe43fc2363809d83c6dc8555ebf70 558 Gene3D G3DSA:3.40.50.300 7 285 2.5E-54 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS09820 4edfe43fc2363809d83c6dc8555ebf70 558 SUPERFAMILY SSF52540 314 507 7.7E-45 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS09820 4edfe43fc2363809d83c6dc8555ebf70 558 TIGRFAM TIGR03719 ABC_ABC_ChvD: ATP-binding cassette protein, ChvD family 3 555 2.9E-270 T 06-07-2017 IPR022374 ABC transporter, ATP-binding protein, ChvD BWK49_RS09820 4edfe43fc2363809d83c6dc8555ebf70 558 Gene3D G3DSA:3.40.50.300 336 512 5.2E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS07965 18bccb2f343892b4ee90f6fa2ecc35b8 277 SUPERFAMILY SSF55073 104 273 9.16E-43 T 06-07-2017 IPR029787 Nucleotide cyclase BWK49_RS07965 18bccb2f343892b4ee90f6fa2ecc35b8 277 Gene3D G3DSA:3.30.70.1230 105 272 3.5E-36 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 BWK49_RS07965 18bccb2f343892b4ee90f6fa2ecc35b8 277 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 105 260 1.3E-22 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 BWK49_RS07965 18bccb2f343892b4ee90f6fa2ecc35b8 277 SMART SM00044 31 250 9.6E-7 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 BWK49_RS23850 6f06a052d2c30c82d194b9b4bc767756 207 SUPERFAMILY SSF53067 108 191 3.37E-8 T 06-07-2017 BWK49_RS23850 6f06a052d2c30c82d194b9b4bc767756 207 Pfam PF00814 Glycoprotease family 35 144 1.1E-26 T 06-07-2017 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 BWK49_RS23850 6f06a052d2c30c82d194b9b4bc767756 207 Gene3D G3DSA:3.30.420.40 3 127 2.1E-35 T 06-07-2017 BWK49_RS23850 6f06a052d2c30c82d194b9b4bc767756 207 SUPERFAMILY SSF53067 3 102 8.2E-22 T 06-07-2017 BWK49_RS23850 6f06a052d2c30c82d194b9b4bc767756 207 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 4 201 2.0E-46 T 06-07-2017 IPR022496 tRNA threonylcarbamoyl adenosine modification protein YeaZ GO:0002949 BWK49_RS27085 d03875dfc04c69b0411d78a7b96b9e2d 1018 Pfam PF03176 MMPL family 454 703 1.1E-35 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 BWK49_RS27085 d03875dfc04c69b0411d78a7b96b9e2d 1018 Pfam PF03176 MMPL family 49 368 4.5E-37 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 BWK49_RS27085 d03875dfc04c69b0411d78a7b96b9e2d 1018 SUPERFAMILY SSF82866 474 701 3.01E-25 T 06-07-2017 BWK49_RS27085 d03875dfc04c69b0411d78a7b96b9e2d 1018 SUPERFAMILY SSF82866 145 335 1.57E-28 T 06-07-2017 BWK49_RS27085 d03875dfc04c69b0411d78a7b96b9e2d 1018 Gene3D G3DSA:1.20.1640.10 483 705 4.6E-30 T 06-07-2017 BWK49_RS27085 d03875dfc04c69b0411d78a7b96b9e2d 1018 Gene3D G3DSA:1.20.1640.10 124 338 3.7E-29 T 06-07-2017 BWK49_RS10050 a5c1a85f63fdc12c35cf382cb9c28450 409 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 12 397 4.4E-139 T 06-07-2017 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 BWK49_RS10050 a5c1a85f63fdc12c35cf382cb9c28450 409 Pfam PF00171 Aldehyde dehydrogenase family 3 283 1.7E-15 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 BWK49_RS10050 a5c1a85f63fdc12c35cf382cb9c28450 409 Pfam PF00171 Aldehyde dehydrogenase family 310 398 8.2E-6 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 BWK49_RS10050 a5c1a85f63fdc12c35cf382cb9c28450 409 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 314 335 - T 06-07-2017 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 BWK49_RS10050 a5c1a85f63fdc12c35cf382cb9c28450 409 Gene3D G3DSA:3.40.309.10 226 365 9.2E-38 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 BWK49_RS10050 a5c1a85f63fdc12c35cf382cb9c28450 409 SUPERFAMILY SSF53720 4 407 2.09E-113 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 BWK49_RS10050 a5c1a85f63fdc12c35cf382cb9c28450 409 PIRSF PIRSF000151 1 408 9.6E-169 T 06-07-2017 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 BWK49_RS10050 a5c1a85f63fdc12c35cf382cb9c28450 409 Gene3D G3DSA:3.40.605.10 366 407 4.0E-101 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 BWK49_RS10050 a5c1a85f63fdc12c35cf382cb9c28450 409 Gene3D G3DSA:3.40.605.10 3 223 4.0E-101 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 BWK49_RS10050 a5c1a85f63fdc12c35cf382cb9c28450 409 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 4 407 41.319 T 06-07-2017 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 BWK49_RS23615 bd630e41e1b34bc65776048b8103b50e 380 Gene3D G3DSA:3.40.50.1000 288 378 1.1E-42 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS23615 bd630e41e1b34bc65776048b8103b50e 380 Gene3D G3DSA:3.40.50.1000 137 210 1.1E-42 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS23615 bd630e41e1b34bc65776048b8103b50e 380 SUPERFAMILY SSF56784 138 375 8.01E-42 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS23615 bd630e41e1b34bc65776048b8103b50e 380 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 139 340 1.5E-16 T 06-07-2017 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 BWK49_RS23615 bd630e41e1b34bc65776048b8103b50e 380 TIGRFAM TIGR00685 T6PP: trehalose-phosphatase 134 375 4.1E-79 T 06-07-2017 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 BWK49_RS23615 bd630e41e1b34bc65776048b8103b50e 380 SUPERFAMILY SSF56784 45 106 4.95E-7 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS23615 bd630e41e1b34bc65776048b8103b50e 380 Pfam PF02358 Trehalose-phosphatase 140 364 5.5E-68 T 06-07-2017 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 BWK49_RS23615 bd630e41e1b34bc65776048b8103b50e 380 Gene3D G3DSA:3.40.50.1000 46 106 4.2E-9 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS11410 95197343484ff4e6f7272bcc4384bad2 303 SUPERFAMILY SSF54427 184 299 3.07E-15 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS11410 95197343484ff4e6f7272bcc4384bad2 303 Pfam PF08281 Sigma-70, region 4 124 171 1.1E-7 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS11410 95197343484ff4e6f7272bcc4384bad2 303 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 16 173 5.7E-16 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS11410 95197343484ff4e6f7272bcc4384bad2 303 Gene3D G3DSA:1.10.1740.10 15 84 1.1E-12 T 06-07-2017 BWK49_RS11410 95197343484ff4e6f7272bcc4384bad2 303 Gene3D G3DSA:3.10.450.50 183 292 4.8E-10 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS11410 95197343484ff4e6f7272bcc4384bad2 303 SUPERFAMILY SSF88946 15 103 2.35E-13 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS11410 95197343484ff4e6f7272bcc4384bad2 303 Pfam PF04542 Sigma-70 region 2 22 83 3.7E-11 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS11410 95197343484ff4e6f7272bcc4384bad2 303 SUPERFAMILY SSF88659 114 172 5.05E-9 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS11410 95197343484ff4e6f7272bcc4384bad2 303 Gene3D G3DSA:1.10.10.10 117 172 6.2E-9 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS13780 fb89621f7f5c9a86d6b22a792955a7da 356 SUPERFAMILY SSF52540 5 245 2.88E-84 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS13780 fb89621f7f5c9a86d6b22a792955a7da 356 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 BWK49_RS13780 fb89621f7f5c9a86d6b22a792955a7da 356 Pfam PF00005 ABC transporter 21 163 4.5E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 BWK49_RS13780 fb89621f7f5c9a86d6b22a792955a7da 356 Gene3D G3DSA:2.40.50.140 278 340 3.2E-13 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS13780 fb89621f7f5c9a86d6b22a792955a7da 356 SMART SM00382 30 213 3.1E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS13780 fb89621f7f5c9a86d6b22a792955a7da 356 Gene3D G3DSA:3.40.50.300 4 236 5.0E-74 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS13780 fb89621f7f5c9a86d6b22a792955a7da 356 Pfam PF08402 TOBE domain 275 348 1.2E-7 T 06-07-2017 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 BWK49_RS13780 fb89621f7f5c9a86d6b22a792955a7da 356 SUPERFAMILY SSF50331 238 355 1.31E-23 T 06-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal BWK49_RS22115 dda512fc0a2deac14a93598cba986672 299 Gene3D G3DSA:3.40.50.1820 5 283 6.6E-53 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS22115 dda512fc0a2deac14a93598cba986672 299 SUPERFAMILY SSF53474 6 283 3.27E-51 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS22115 dda512fc0a2deac14a93598cba986672 299 Pfam PF12146 Serine aminopeptidase, S33 24 256 5.9E-19 T 06-07-2017 IPR022742 Serine aminopeptidase, S33 BWK49_RS13925 52afd62fa48a384a4b4a602ce95d3887 209 Gene3D G3DSA:1.10.357.10 1 199 8.1E-27 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS13925 52afd62fa48a384a4b4a602ce95d3887 209 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 55 1.9E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS13925 52afd62fa48a384a4b4a602ce95d3887 209 SUPERFAMILY SSF46689 3 75 3.85E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS01510 57bb93e53754c7f8ecd162317ef82687 303 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 17 281 1.4E-77 T 06-07-2017 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 BWK49_RS01510 57bb93e53754c7f8ecd162317ef82687 303 Gene3D G3DSA:3.40.50.150 23 217 1.2E-14 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS01510 57bb93e53754c7f8ecd162317ef82687 303 SUPERFAMILY SSF53335 15 293 3.19E-73 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS01510 57bb93e53754c7f8ecd162317ef82687 303 Pfam PF04072 Leucine carboxyl methyltransferase 19 203 1.4E-61 T 06-07-2017 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 BWK49_RS09250 cc0f691010e1d584042db353af6b1e38 270 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 110 130 - T 06-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 BWK49_RS09250 cc0f691010e1d584042db353af6b1e38 270 SUPERFAMILY SSF52096 4 268 4.8E-72 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS09250 cc0f691010e1d584042db353af6b1e38 270 Pfam PF00378 Enoyl-CoA hydratase/isomerase 18 268 2.5E-46 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 BWK49_RS09250 cc0f691010e1d584042db353af6b1e38 270 Gene3D G3DSA:1.10.12.10 211 268 1.9E-16 T 06-07-2017 IPR014748 Crontonase, C-terminal BWK49_RS09250 cc0f691010e1d584042db353af6b1e38 270 Gene3D G3DSA:3.90.226.10 6 208 4.6E-58 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS24900 e1ac44c524022ccfdce119d2e97c0a78 360 Pfam PF00355 Rieske [2Fe-2S] domain 56 138 2.8E-16 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS24900 e1ac44c524022ccfdce119d2e97c0a78 360 SUPERFAMILY SSF50022 52 162 2.1E-30 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS24900 e1ac44c524022ccfdce119d2e97c0a78 360 SUPERFAMILY SSF55961 154 355 2.34E-18 T 06-07-2017 BWK49_RS24900 e1ac44c524022ccfdce119d2e97c0a78 360 Gene3D G3DSA:2.102.10.10 55 169 2.8E-28 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS01695 4ca47d1ba40a22d330d7c8fa3b91f80a 268 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 258 1.2E-40 T 06-07-2017 BWK49_RS01695 4ca47d1ba40a22d330d7c8fa3b91f80a 268 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS01695 4ca47d1ba40a22d330d7c8fa3b91f80a 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.4E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS01695 4ca47d1ba40a22d330d7c8fa3b91f80a 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 1.4E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS01695 4ca47d1ba40a22d330d7c8fa3b91f80a 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 1.4E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS01695 4ca47d1ba40a22d330d7c8fa3b91f80a 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 1.4E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS01695 4ca47d1ba40a22d330d7c8fa3b91f80a 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 1.4E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS01695 4ca47d1ba40a22d330d7c8fa3b91f80a 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 1.4E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS01695 4ca47d1ba40a22d330d7c8fa3b91f80a 268 SUPERFAMILY SSF51735 6 258 4.5E-55 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS01695 4ca47d1ba40a22d330d7c8fa3b91f80a 268 Gene3D G3DSA:3.40.50.720 3 258 1.1E-57 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS25550 2ab399acf97161a15c82925414f27c90 215 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 91 191 1.5E-30 T 06-07-2017 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 BWK49_RS25550 2ab399acf97161a15c82925414f27c90 215 SUPERFAMILY SSF54719 90 199 7.73E-37 T 06-07-2017 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 BWK49_RS25550 2ab399acf97161a15c82925414f27c90 215 Gene3D G3DSA:1.10.287.990 21 84 6.1E-20 T 06-07-2017 BWK49_RS25550 2ab399acf97161a15c82925414f27c90 215 PRINTS PR01703 Manganese superoxide dismutase signature 7 18 3.8E-18 T 06-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 BWK49_RS25550 2ab399acf97161a15c82925414f27c90 215 PRINTS PR01703 Manganese superoxide dismutase signature 28 41 3.8E-18 T 06-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 BWK49_RS25550 2ab399acf97161a15c82925414f27c90 215 PRINTS PR01703 Manganese superoxide dismutase signature 67 80 3.8E-18 T 06-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 BWK49_RS25550 2ab399acf97161a15c82925414f27c90 215 PRINTS PR01703 Manganese superoxide dismutase signature 158 170 3.8E-18 T 06-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 BWK49_RS25550 2ab399acf97161a15c82925414f27c90 215 PRINTS PR01703 Manganese superoxide dismutase signature 120 128 3.8E-18 T 06-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 BWK49_RS25550 2ab399acf97161a15c82925414f27c90 215 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 160 167 - T 06-07-2017 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 BWK49_RS25550 2ab399acf97161a15c82925414f27c90 215 PIRSF PIRSF000349 1 201 1.2E-67 T 06-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 BWK49_RS25550 2ab399acf97161a15c82925414f27c90 215 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 4 84 3.0E-27 T 06-07-2017 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 BWK49_RS25550 2ab399acf97161a15c82925414f27c90 215 SUPERFAMILY SSF46609 3 86 2.23E-27 T 06-07-2017 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 BWK49_RS09265 d42e7a7fcc571a570da209752b305c01 298 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 124 144 - T 06-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 BWK49_RS09265 d42e7a7fcc571a570da209752b305c01 298 Gene3D G3DSA:3.90.226.10 12 248 4.8E-48 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS09265 d42e7a7fcc571a570da209752b305c01 298 Pfam PF00378 Enoyl-CoA hydratase/isomerase 19 276 1.6E-29 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 BWK49_RS09265 d42e7a7fcc571a570da209752b305c01 298 SUPERFAMILY SSF52096 9 277 1.12E-46 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS16825 0a6a7eedd6c88ca6af83689edef0a827 101 Gene3D G3DSA:1.10.10.10 4 99 1.1E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS16825 0a6a7eedd6c88ca6af83689edef0a827 101 SMART SM00418 7 99 6.2E-6 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 BWK49_RS16825 0a6a7eedd6c88ca6af83689edef0a827 101 SUPERFAMILY SSF46785 4 98 4.48E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS16825 0a6a7eedd6c88ca6af83689edef0a827 101 Pfam PF12840 Helix-turn-helix domain 7 78 4.4E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS19175 afed87c9cb0f2791f62c209f5334b8ad 295 SUPERFAMILY SSF46785 9 78 5.18E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS19175 afed87c9cb0f2791f62c209f5334b8ad 295 SMART SM00346 7 97 2.0E-7 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 BWK49_RS19175 afed87c9cb0f2791f62c209f5334b8ad 295 Pfam PF09339 IclR helix-turn-helix domain 10 60 7.7E-8 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 BWK49_RS19175 afed87c9cb0f2791f62c209f5334b8ad 295 Gene3D G3DSA:1.10.10.10 7 79 9.3E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS19175 afed87c9cb0f2791f62c209f5334b8ad 295 Gene3D G3DSA:3.30.450.40 83 202 6.8E-14 T 06-07-2017 IPR029016 GAF domain-like BWK49_RS19175 afed87c9cb0f2791f62c209f5334b8ad 295 Gene3D G3DSA:3.30.450.40 243 290 6.8E-14 T 06-07-2017 IPR029016 GAF domain-like BWK49_RS19175 afed87c9cb0f2791f62c209f5334b8ad 295 SUPERFAMILY SSF55781 234 290 4.37E-10 T 06-07-2017 IPR029016 GAF domain-like BWK49_RS19175 afed87c9cb0f2791f62c209f5334b8ad 295 SUPERFAMILY SSF55781 87 185 4.37E-10 T 06-07-2017 IPR029016 GAF domain-like BWK49_RS20790 3372ae585c70125443726620f463e114 300 Pfam PF00106 short chain dehydrogenase 16 147 1.8E-20 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS20790 3372ae585c70125443726620f463e114 300 Gene3D G3DSA:3.40.50.720 13 258 2.7E-47 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS20790 3372ae585c70125443726620f463e114 300 SUPERFAMILY SSF51735 12 248 1.46E-45 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS20790 3372ae585c70125443726620f463e114 300 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 89 100 1.5E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS20790 3372ae585c70125443726620f463e114 300 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 1.5E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS20790 3372ae585c70125443726620f463e114 300 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 17 34 1.5E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS17915 e3ffa465f25736ac649ecbf0725d2276 194 SUPERFAMILY SSF46689 5 73 5.13E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS17915 e3ffa465f25736ac649ecbf0725d2276 194 Gene3D G3DSA:1.10.357.10 11 185 2.8E-26 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS17915 e3ffa465f25736ac649ecbf0725d2276 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 1.5E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS17915 e3ffa465f25736ac649ecbf0725d2276 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 1.5E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS17915 e3ffa465f25736ac649ecbf0725d2276 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 5.0E-17 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS26525 20ffd35071ea9adce8fc145cb7a7e261 491 SUPERFAMILY SSF52777 62 214 1.33E-15 T 06-07-2017 BWK49_RS26525 20ffd35071ea9adce8fc145cb7a7e261 491 SUPERFAMILY SSF52777 227 460 1.22E-17 T 06-07-2017 BWK49_RS26525 20ffd35071ea9adce8fc145cb7a7e261 491 Pfam PF00668 Condensation domain 67 333 1.5E-10 T 06-07-2017 IPR001242 Condensation domain BWK49_RS15515 7946815075506cb4d70b57f1a103ac51 372 SUPERFAMILY SSF55920 150 369 1.57E-36 T 06-07-2017 IPR000994 Peptidase M24, structural domain BWK49_RS15515 7946815075506cb4d70b57f1a103ac51 372 SUPERFAMILY SSF53092 4 148 2.96E-18 T 06-07-2017 IPR028980 Creatinase/Aminopeptidase P, N-terminal BWK49_RS15515 7946815075506cb4d70b57f1a103ac51 372 Pfam PF01321 Creatinase/Prolidase N-terminal domain 16 150 1.4E-16 T 06-07-2017 IPR000587 Creatinase, N-terminal GO:0016787 BWK49_RS15515 7946815075506cb4d70b57f1a103ac51 372 Gene3D G3DSA:3.90.230.10 150 369 1.2E-31 T 06-07-2017 IPR000994 Peptidase M24, structural domain BWK49_RS15515 7946815075506cb4d70b57f1a103ac51 372 Pfam PF00557 Metallopeptidase family M24 159 359 3.0E-21 T 06-07-2017 IPR000994 Peptidase M24, structural domain BWK49_RS15515 7946815075506cb4d70b57f1a103ac51 372 Gene3D G3DSA:3.40.350.10 15 148 2.2E-15 T 06-07-2017 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal BWK49_RS18710 ed0c2ce90025096bc1e75335b3124d29 294 PIRSF PIRSF001365 4 293 3.1E-84 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 BWK49_RS18710 ed0c2ce90025096bc1e75335b3124d29 294 PRINTS PR00146 Dihydrodipicolinate synthase signature 134 151 1.7E-11 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 BWK49_RS18710 ed0c2ce90025096bc1e75335b3124d29 294 PRINTS PR00146 Dihydrodipicolinate synthase signature 77 95 1.7E-11 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 BWK49_RS18710 ed0c2ce90025096bc1e75335b3124d29 294 PRINTS PR00146 Dihydrodipicolinate synthase signature 109 125 1.7E-11 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 BWK49_RS18710 ed0c2ce90025096bc1e75335b3124d29 294 PRINTS PR00146 Dihydrodipicolinate synthase signature 41 62 1.7E-11 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 BWK49_RS18710 ed0c2ce90025096bc1e75335b3124d29 294 SMART SM01130 8 293 3.6E-99 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 BWK49_RS18710 ed0c2ce90025096bc1e75335b3124d29 294 Gene3D G3DSA:3.20.20.70 7 292 6.1E-96 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 BWK49_RS18710 ed0c2ce90025096bc1e75335b3124d29 294 Pfam PF00701 Dihydrodipicolinate synthetase family 9 292 1.4E-54 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 BWK49_RS18710 ed0c2ce90025096bc1e75335b3124d29 294 SUPERFAMILY SSF51569 7 292 1.26E-85 T 06-07-2017 BWK49_RS15095 2162cb8bd7c8b1e7382dad999942fe11 132 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 4 131 2.0E-50 T 06-07-2017 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 BWK49_RS15095 2162cb8bd7c8b1e7382dad999942fe11 132 Gene3D G3DSA:2.40.50.100 7 131 1.2E-47 T 06-07-2017 BWK49_RS15095 2162cb8bd7c8b1e7382dad999942fe11 132 Pfam PF01597 Glycine cleavage H-protein 8 130 6.2E-43 T 06-07-2017 IPR002930 Glycine cleavage system H-protein BWK49_RS15095 2162cb8bd7c8b1e7382dad999942fe11 132 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 49 78 - T 06-07-2017 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 BWK49_RS15095 2162cb8bd7c8b1e7382dad999942fe11 132 SUPERFAMILY SSF51230 4 130 6.02E-41 T 06-07-2017 IPR011053 Single hybrid motif BWK49_RS15095 2162cb8bd7c8b1e7382dad999942fe11 132 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 5 131 30.133 T 06-07-2017 IPR002930 Glycine cleavage system H-protein BWK49_RS18895 c3a68254e050a26fc2cefa39b216c733 340 SUPERFAMILY SSF55811 173 312 2.84E-20 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 BWK49_RS18895 c3a68254e050a26fc2cefa39b216c733 340 ProSitePatterns PS00893 Nudix box signature. 215 236 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 BWK49_RS18895 c3a68254e050a26fc2cefa39b216c733 340 Gene3D G3DSA:1.20.1440.20 18 133 9.9E-4 T 06-07-2017 IPR023353 LemA-like domain BWK49_RS18895 c3a68254e050a26fc2cefa39b216c733 340 Pfam PF00293 NUDIX domain 177 310 4.4E-21 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 BWK49_RS18895 c3a68254e050a26fc2cefa39b216c733 340 Gene3D G3DSA:3.90.79.10 176 310 2.9E-21 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 BWK49_RS23620 f78dd6f4f345cfce435de9c643d69c27 288 SUPERFAMILY SSF54637 7 155 2.55E-38 T 06-07-2017 IPR029069 HotDog domain BWK49_RS23620 f78dd6f4f345cfce435de9c643d69c27 288 Gene3D G3DSA:3.10.129.10 142 271 2.6E-41 T 06-07-2017 IPR029069 HotDog domain BWK49_RS23620 f78dd6f4f345cfce435de9c643d69c27 288 Gene3D G3DSA:3.10.129.10 1 141 3.5E-43 T 06-07-2017 IPR029069 HotDog domain BWK49_RS23620 f78dd6f4f345cfce435de9c643d69c27 288 SUPERFAMILY SSF54637 160 271 6.02E-30 T 06-07-2017 IPR029069 HotDog domain BWK49_RS23620 f78dd6f4f345cfce435de9c643d69c27 288 Pfam PF01575 MaoC like domain 161 267 2.0E-31 T 06-07-2017 IPR002539 MaoC-like domain BWK49_RS23620 f78dd6f4f345cfce435de9c643d69c27 288 Pfam PF13452 N-terminal half of MaoC dehydratase 7 127 4.6E-8 T 06-07-2017 BWK49_RS25350 ef865bc8f13840143354d79b4ee79f75 338 Gene3D G3DSA:3.30.420.150 125 305 4.5E-47 T 06-07-2017 BWK49_RS25350 ef865bc8f13840143354d79b4ee79f75 338 SUPERFAMILY SSF53067 2 125 1.45E-30 T 06-07-2017 BWK49_RS25350 ef865bc8f13840143354d79b4ee79f75 338 Gene3D G3DSA:3.30.420.40 2 122 2.5E-34 T 06-07-2017 BWK49_RS25350 ef865bc8f13840143354d79b4ee79f75 338 Pfam PF02541 Ppx/GppA phosphatase family 17 307 1.6E-89 T 06-07-2017 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 BWK49_RS25350 ef865bc8f13840143354d79b4ee79f75 338 SUPERFAMILY SSF53067 130 305 2.07E-34 T 06-07-2017 BWK49_RS02630 918245f33876d696f944c58a7dd5fe06 217 Pfam PF13559 Domain of unknown function (DUF4129) 121 190 5.9E-12 T 06-07-2017 IPR025403 Domain of unknown function DUF4129 BWK49_RS21105 843cac1dc7d4160596ab57624a53953c 460 SUPERFAMILY SSF55961 5 137 1.38E-15 T 06-07-2017 BWK49_RS21105 843cac1dc7d4160596ab57624a53953c 460 Pfam PF01370 NAD dependent epimerase/dehydratase family 155 360 3.7E-13 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 BWK49_RS21105 843cac1dc7d4160596ab57624a53953c 460 Pfam PF08338 Domain of unknown function (DUF1731) 398 446 4.0E-15 T 06-07-2017 IPR013549 Domain of unknown function DUF1731 BWK49_RS21105 843cac1dc7d4160596ab57624a53953c 460 TIGRFAM TIGR01777 yfcH: TIGR01777 family protein 155 443 3.6E-90 T 06-07-2017 IPR010099 Epimerase family protein SDR39U1 BWK49_RS21105 843cac1dc7d4160596ab57624a53953c 460 SUPERFAMILY SSF51735 151 445 1.29E-36 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS21105 843cac1dc7d4160596ab57624a53953c 460 Gene3D G3DSA:3.40.50.720 154 393 9.6E-23 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS00435 fd99dbd57e9d2ec8caf0e02cde3acc96 304 SMART SM00849 72 279 2.0E-21 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS00435 fd99dbd57e9d2ec8caf0e02cde3acc96 304 Pfam PF00753 Metallo-beta-lactamase superfamily 72 279 2.0E-25 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS00435 fd99dbd57e9d2ec8caf0e02cde3acc96 304 SUPERFAMILY SSF56281 15 301 1.21E-46 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS00435 fd99dbd57e9d2ec8caf0e02cde3acc96 304 Gene3D G3DSA:3.60.15.10 16 300 1.8E-49 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS25875 7c0e1d92b02d0cccde562860e778852b 69 Pfam PF02597 ThiS family 7 69 1.5E-8 T 06-07-2017 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 BWK49_RS25875 7c0e1d92b02d0cccde562860e778852b 69 SUPERFAMILY SSF54285 3 68 1.98E-10 T 06-07-2017 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp BWK49_RS25875 7c0e1d92b02d0cccde562860e778852b 69 Gene3D G3DSA:3.10.20.30 1 69 2.0E-22 T 06-07-2017 IPR012675 Beta-grasp domain BWK49_RS25875 7c0e1d92b02d0cccde562860e778852b 69 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 3 69 3.8E-17 T 06-07-2017 IPR010035 ThiS, thiamine-biosynthesis BWK49_RS27175 5984d062c58bd2a345a7392127fdbf56 277 PRINTS PR00111 Alpha/beta hydrolase fold signature 55 70 1.3E-9 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS27175 5984d062c58bd2a345a7392127fdbf56 277 PRINTS PR00111 Alpha/beta hydrolase fold signature 104 117 1.3E-9 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS27175 5984d062c58bd2a345a7392127fdbf56 277 PRINTS PR00111 Alpha/beta hydrolase fold signature 118 131 1.3E-9 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS27175 5984d062c58bd2a345a7392127fdbf56 277 PRINTS PR00111 Alpha/beta hydrolase fold signature 216 230 1.3E-9 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS27175 5984d062c58bd2a345a7392127fdbf56 277 Gene3D G3DSA:3.40.50.1820 3 276 3.6E-50 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS27175 5984d062c58bd2a345a7392127fdbf56 277 SUPERFAMILY SSF53474 7 276 2.95E-46 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS27175 5984d062c58bd2a345a7392127fdbf56 277 Pfam PF12146 Serine aminopeptidase, S33 26 261 8.7E-78 T 06-07-2017 IPR022742 Serine aminopeptidase, S33 BWK49_RS13540 4e609bf2a67bc33a7f0f5857219ec60d 252 Gene3D G3DSA:3.40.50.1820 34 220 3.6E-20 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS13540 4e609bf2a67bc33a7f0f5857219ec60d 252 SUPERFAMILY SSF53474 41 214 3.44E-24 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS13330 ec624521dcfc100c7440ddfc3d7140c0 276 Pfam PF02405 Permease MlaE 60 263 1.8E-54 T 06-07-2017 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 BWK49_RS22830 16149fb565b4d4715b6eaa1fd6dd33c2 427 ProSitePatterns PS00104 EPSP synthase signature 1. 86 100 - T 06-07-2017 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 BWK49_RS22830 16149fb565b4d4715b6eaa1fd6dd33c2 427 Gene3D G3DSA:3.65.10.10 218 418 2.9E-45 T 06-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 BWK49_RS22830 16149fb565b4d4715b6eaa1fd6dd33c2 427 PIRSF PIRSF000505 1 424 8.4E-114 T 06-07-2017 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 BWK49_RS22830 16149fb565b4d4715b6eaa1fd6dd33c2 427 SUPERFAMILY SSF55205 2 417 2.22E-93 T 06-07-2017 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 BWK49_RS22830 16149fb565b4d4715b6eaa1fd6dd33c2 427 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 2 413 1.6E-111 T 06-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 BWK49_RS22830 16149fb565b4d4715b6eaa1fd6dd33c2 427 Gene3D G3DSA:3.65.10.10 9 212 3.0E-55 T 06-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 BWK49_RS22830 16149fb565b4d4715b6eaa1fd6dd33c2 427 ProSitePatterns PS00885 EPSP synthase signature 2. 334 352 - T 06-07-2017 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 BWK49_RS22830 16149fb565b4d4715b6eaa1fd6dd33c2 427 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 4 418 2.2E-99 T 06-07-2017 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 BWK49_RS22830 16149fb565b4d4715b6eaa1fd6dd33c2 427 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 1 421 27.049 T 06-07-2017 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 BWK49_RS02570 c3017bcbbbf95f76e7262829001791fe 321 Pfam PF10017 Histidine-specific methyltransferase, SAM-dependent 192 316 4.8E-40 T 06-07-2017 IPR019257 Histidine-specific methyltransferase, SAM-dependent BWK49_RS02570 c3017bcbbbf95f76e7262829001791fe 321 Gene3D G3DSA:3.40.50.150 50 153 3.8E-7 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS02570 c3017bcbbbf95f76e7262829001791fe 321 PIRSF PIRSF018005 2 321 4.6E-136 T 06-07-2017 IPR017804 Methyltransferase EgtD-like BWK49_RS02570 c3017bcbbbf95f76e7262829001791fe 321 TIGRFAM TIGR03438 egtD_ergothio: dimethylhistidine N-methyltransferase 18 318 3.2E-113 T 06-07-2017 IPR017804 Methyltransferase EgtD-like BWK49_RS02570 c3017bcbbbf95f76e7262829001791fe 321 SUPERFAMILY SSF53335 35 212 5.49E-14 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS02570 c3017bcbbbf95f76e7262829001791fe 321 Hamap MF_02037 Histidine N-alpha-methyltransferase [egtD]. 5 321 54.225 T 06-07-2017 IPR032888 Histidine N-alpha-methyltransferase, Actinobacteria-type GO:0008276|GO:0052699 KEGG: 00340+2.1.1.44|MetaCyc: PWY-7255|MetaCyc: PWY-7550 BWK49_RS09455 4fc8b7bfdebdd52e0d68dfcea126631e 385 SUPERFAMILY SSF51735 171 346 8.3E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS09455 4fc8b7bfdebdd52e0d68dfcea126631e 385 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 72 86 - T 06-07-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 BWK49_RS09455 4fc8b7bfdebdd52e0d68dfcea126631e 385 Gene3D G3DSA:3.40.50.720 202 325 1.9E-24 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS09455 4fc8b7bfdebdd52e0d68dfcea126631e 385 Pfam PF00107 Zinc-binding dehydrogenase 209 340 3.2E-20 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 BWK49_RS09455 4fc8b7bfdebdd52e0d68dfcea126631e 385 SUPERFAMILY SSF50129 1 205 1.62E-57 T 06-07-2017 IPR011032 GroES-like BWK49_RS09455 4fc8b7bfdebdd52e0d68dfcea126631e 385 Gene3D G3DSA:3.90.180.10 2 201 1.2E-56 T 06-07-2017 IPR011032 GroES-like BWK49_RS09455 4fc8b7bfdebdd52e0d68dfcea126631e 385 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 167 1.4E-25 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 BWK49_RS09455 4fc8b7bfdebdd52e0d68dfcea126631e 385 TIGRFAM TIGR03989 Rxyl_3153: NDMA-dependent alcohol dehydrogenase, Rxyl_3153 family 2 382 9.4E-146 T 06-07-2017 IPR023921 Alcohol dehydrogenase, zinc-type, actinomycetes KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396 BWK49_RS09455 4fc8b7bfdebdd52e0d68dfcea126631e 385 SMART SM00829 13 380 6.5E-4 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 BWK49_RS21430 a062e33eeda97b8dbc2376af7a6f6ee2 231 SUPERFAMILY SSF55469 13 74 6.67E-38 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 BWK49_RS21430 a062e33eeda97b8dbc2376af7a6f6ee2 231 SUPERFAMILY SSF55469 113 227 6.67E-38 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 BWK49_RS21430 a062e33eeda97b8dbc2376af7a6f6ee2 231 Gene3D G3DSA:3.40.109.10 13 226 1.0E-37 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 BWK49_RS21430 a062e33eeda97b8dbc2376af7a6f6ee2 231 Pfam PF00881 Nitroreductase family 23 203 7.5E-26 T 06-07-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 BWK49_RS02840 0250fa356b23a15083e64eb26ddff99e 545 Gene3D G3DSA:3.10.105.10 327 516 4.3E-36 T 06-07-2017 BWK49_RS02840 0250fa356b23a15083e64eb26ddff99e 545 PIRSF PIRSF002741 34 535 1.6E-53 T 06-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 BWK49_RS02840 0250fa356b23a15083e64eb26ddff99e 545 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 78 466 1.5E-43 T 06-07-2017 IPR000914 Solute-binding protein family 5 domain BWK49_RS02840 0250fa356b23a15083e64eb26ddff99e 545 SUPERFAMILY SSF53850 34 541 2.53E-83 T 06-07-2017 BWK49_RS02840 0250fa356b23a15083e64eb26ddff99e 545 Gene3D G3DSA:3.90.76.10 45 208 7.9E-28 T 06-07-2017 BWK49_RS02840 0250fa356b23a15083e64eb26ddff99e 545 Gene3D G3DSA:3.40.190.10 209 326 2.7E-17 T 06-07-2017 BWK49_RS23955 fafc67cb035cf36a1b12f20237d4517a 413 TIGRFAM TIGR03931 T7SS_Rv3446c: type VII secretion-associated protein, Rv3446c family 256 411 5.3E-43 T 06-07-2017 IPR023840 Type VII secretion system Rv3446c BWK49_RS00945 1d7f50a1b068dc60e9d75051968f708c 335 Gene3D G3DSA:3.20.20.140 97 331 6.0E-52 T 06-07-2017 BWK49_RS00945 1d7f50a1b068dc60e9d75051968f708c 335 SMART SM00481 98 177 6.3E-20 T 06-07-2017 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 BWK49_RS00945 1d7f50a1b068dc60e9d75051968f708c 335 SUPERFAMILY SSF47802 3 82 3.66E-14 T 06-07-2017 IPR010996 DNA polymerase beta-like, N-terminal domain BWK49_RS00945 1d7f50a1b068dc60e9d75051968f708c 335 Gene3D G3DSA:1.10.150.110 4 80 1.1E-10 T 06-07-2017 IPR027421 DNA polymerase family X lyase domain BWK49_RS00945 1d7f50a1b068dc60e9d75051968f708c 335 Pfam PF14716 Helix-hairpin-helix domain 4 68 7.3E-15 T 06-07-2017 IPR010996 DNA polymerase beta-like, N-terminal domain BWK49_RS00945 1d7f50a1b068dc60e9d75051968f708c 335 SUPERFAMILY SSF89550 97 329 4.32E-52 T 06-07-2017 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 BWK49_RS00945 1d7f50a1b068dc60e9d75051968f708c 335 PIRSF PIRSF036978 1 335 4.4E-202 T 06-07-2017 IPR017078 Uncharacterised conserved protein UCP036978, histidinol phosphatase-related hydrolase, SCO0789 BWK49_RS00945 1d7f50a1b068dc60e9d75051968f708c 335 Pfam PF02811 PHP domain 99 196 9.7E-10 T 06-07-2017 IPR004013 PHP domain GO:0003824 BWK49_RS17245 79fd0a08856d3c907592145fc904c510 291 SUPERFAMILY SSF54637 7 117 4.88E-28 T 06-07-2017 IPR029069 HotDog domain BWK49_RS17245 79fd0a08856d3c907592145fc904c510 291 Pfam PF02551 Acyl-CoA thioesterase 151 282 2.8E-45 T 06-07-2017 IPR025652 Acyl-CoA thioesterase II domain BWK49_RS17245 79fd0a08856d3c907592145fc904c510 291 Pfam PF02551 Acyl-CoA thioesterase 64 108 4.5E-5 T 06-07-2017 IPR025652 Acyl-CoA thioesterase II domain BWK49_RS17245 79fd0a08856d3c907592145fc904c510 291 Gene3D G3DSA:3.10.129.10 130 285 1.3E-40 T 06-07-2017 IPR029069 HotDog domain BWK49_RS17245 79fd0a08856d3c907592145fc904c510 291 Gene3D G3DSA:3.10.129.10 5 112 8.9E-31 T 06-07-2017 IPR029069 HotDog domain BWK49_RS17245 79fd0a08856d3c907592145fc904c510 291 SUPERFAMILY SSF54637 119 283 6.17E-39 T 06-07-2017 IPR029069 HotDog domain BWK49_RS25755 cf07a615158c0b9ca2860b417aef2ae3 1478 Gene3D G3DSA:1.20.1110.10 666 721 6.7E-45 T 06-07-2017 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 BWK49_RS25755 cf07a615158c0b9ca2860b417aef2ae3 1478 Gene3D G3DSA:1.20.1110.10 1164 1423 6.7E-45 T 06-07-2017 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 BWK49_RS25755 cf07a615158c0b9ca2860b417aef2ae3 1478 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 776 790 3.6E-26 T 06-07-2017 BWK49_RS25755 cf07a615158c0b9ca2860b417aef2ae3 1478 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 1115 1125 3.6E-26 T 06-07-2017 BWK49_RS25755 cf07a615158c0b9ca2860b417aef2ae3 1478 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 1093 1104 3.6E-26 T 06-07-2017 BWK49_RS25755 cf07a615158c0b9ca2860b417aef2ae3 1478 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 1219 1231 3.6E-26 T 06-07-2017 BWK49_RS25755 cf07a615158c0b9ca2860b417aef2ae3 1478 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 937 951 3.6E-26 T 06-07-2017 BWK49_RS25755 cf07a615158c0b9ca2860b417aef2ae3 1478 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 1195 1214 3.6E-26 T 06-07-2017 BWK49_RS25755 cf07a615158c0b9ca2860b417aef2ae3 1478 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 1162 1278 1.3E-23 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 BWK49_RS25755 cf07a615158c0b9ca2860b417aef2ae3 1478 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 698 971 1.3E-29 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 BWK49_RS25755 cf07a615158c0b9ca2860b417aef2ae3 1478 Gene3D G3DSA:2.70.150.10 738 837 9.0E-26 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 BWK49_RS25755 cf07a615158c0b9ca2860b417aef2ae3 1478 SUPERFAMILY SSF81665 838 931 1.12E-46 T 06-07-2017 BWK49_RS25755 cf07a615158c0b9ca2860b417aef2ae3 1478 SUPERFAMILY SSF81665 655 724 1.12E-46 T 06-07-2017 BWK49_RS25755 cf07a615158c0b9ca2860b417aef2ae3 1478 SUPERFAMILY SSF81665 1245 1428 1.12E-46 T 06-07-2017 BWK49_RS25755 cf07a615158c0b9ca2860b417aef2ae3 1478 SUPERFAMILY SSF81653 739 837 6.02E-24 T 06-07-2017 BWK49_RS25755 cf07a615158c0b9ca2860b417aef2ae3 1478 Pfam PF00122 E1-E2 ATPase 692 928 1.5E-51 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 BWK49_RS25755 cf07a615158c0b9ca2860b417aef2ae3 1478 Gene3D G3DSA:3.40.1110.10 928 1099 2.0E-15 T 06-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 BWK49_RS25755 cf07a615158c0b9ca2860b417aef2ae3 1478 SUPERFAMILY SSF56784 935 955 5.82E-36 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS25755 cf07a615158c0b9ca2860b417aef2ae3 1478 SUPERFAMILY SSF56784 1041 1300 5.82E-36 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS25755 cf07a615158c0b9ca2860b417aef2ae3 1478 Pfam PF00702 haloacid dehalogenase-like hydrolase 933 1208 2.0E-18 T 06-07-2017 BWK49_RS25755 cf07a615158c0b9ca2860b417aef2ae3 1478 Pfam PF00689 Cation transporting ATPase, C-terminus 1280 1429 5.2E-14 T 06-07-2017 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 BWK49_RS25755 cf07a615158c0b9ca2860b417aef2ae3 1478 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 1044 1062 3.8E-12 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 BWK49_RS25755 cf07a615158c0b9ca2860b417aef2ae3 1478 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 1227 1252 3.8E-12 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 BWK49_RS25755 cf07a615158c0b9ca2860b417aef2ae3 1478 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 1167 1183 3.8E-12 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 BWK49_RS25755 cf07a615158c0b9ca2860b417aef2ae3 1478 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 1195 1211 3.8E-12 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 BWK49_RS08685 727acfe994029e3c1e47216b6dbf71a8 278 SMART SM00987 96 268 1.5E-29 T 06-07-2017 BWK49_RS08685 727acfe994029e3c1e47216b6dbf71a8 278 Pfam PF03167 Uracil DNA glycosylase superfamily 97 271 2.5E-29 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 BWK49_RS08685 727acfe994029e3c1e47216b6dbf71a8 278 Gene3D G3DSA:3.40.470.10 54 276 4.7E-52 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 BWK49_RS08685 727acfe994029e3c1e47216b6dbf71a8 278 SMART SM00986 96 268 1.5E-29 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 BWK49_RS08685 727acfe994029e3c1e47216b6dbf71a8 278 SUPERFAMILY SSF52141 63 273 4.25E-43 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 BWK49_RS27080 e33b39e9d9984006c07600acfbee0ba4 183 TIGRFAM TIGR04530 hemophoreRv0203: hemophore 16 133 1.7E-60 T 06-07-2017 IPR030937 Hemophore Rv0203 GO:0015886|GO:0020037 BWK49_RS27080 e33b39e9d9984006c07600acfbee0ba4 183 TIGRFAM TIGR04529 MTB_hemophore: hemophore-related protein, Rv0203/Rv1174c family 41 117 1.9E-23 T 06-07-2017 IPR032407 Haemophore, haem-binding GO:0020037 BWK49_RS27080 e33b39e9d9984006c07600acfbee0ba4 183 Pfam PF16525 Haemophore, haem-binding 39 116 4.7E-26 T 06-07-2017 IPR032407 Haemophore, haem-binding GO:0020037 BWK49_RS04750 3c641a9edc269f9318ed400625852c4d 217 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 1.5E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS04750 3c641a9edc269f9318ed400625852c4d 217 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 1.5E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS04750 3c641a9edc269f9318ed400625852c4d 217 SUPERFAMILY SSF48498 88 170 1.33E-8 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS04750 3c641a9edc269f9318ed400625852c4d 217 Gene3D G3DSA:1.10.357.10 66 180 1.1E-24 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS04750 3c641a9edc269f9318ed400625852c4d 217 Gene3D G3DSA:1.10.10.60 14 65 3.2E-22 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS04750 3c641a9edc269f9318ed400625852c4d 217 SUPERFAMILY SSF46689 9 90 1.54E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS04750 3c641a9edc269f9318ed400625852c4d 217 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 65 1.6E-17 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS25710 d3ffdc691b7bf885527973d4f6cb2106 212 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 6 197 1.7E-20 T 06-07-2017 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 BWK49_RS25710 d3ffdc691b7bf885527973d4f6cb2106 212 SMART SM00464 6 201 2.7E-32 T 06-07-2017 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 BWK49_RS25710 d3ffdc691b7bf885527973d4f6cb2106 212 SUPERFAMILY SSF88697 6 199 6.46E-37 T 06-07-2017 IPR015947 PUA-like domain BWK49_RS14195 cc1e0446e3df99b994690f8b869aa123 253 Gene3D G3DSA:3.40.50.720 2 251 1.3E-74 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS14195 cc1e0446e3df99b994690f8b869aa123 253 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 185 6.8E-5 T 06-07-2017 BWK49_RS14195 cc1e0446e3df99b994690f8b869aa123 253 SUPERFAMILY SSF51735 6 251 2.26E-70 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS14195 cc1e0446e3df99b994690f8b869aa123 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 138 166 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS14195 cc1e0446e3df99b994690f8b869aa123 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 251 1.0E-54 T 06-07-2017 BWK49_RS14195 cc1e0446e3df99b994690f8b869aa123 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 4.1E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS14195 cc1e0446e3df99b994690f8b869aa123 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 4.1E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS14195 cc1e0446e3df99b994690f8b869aa123 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 4.1E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS14195 cc1e0446e3df99b994690f8b869aa123 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 4.1E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS14195 cc1e0446e3df99b994690f8b869aa123 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 4.1E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS14195 cc1e0446e3df99b994690f8b869aa123 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 4.1E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15450 8e50f743d7bba80005c98fe8921dc2d1 587 Pfam PF07969 Amidohydrolase family 45 206 1.5E-10 T 06-07-2017 IPR013108 Amidohydrolase 3 BWK49_RS15450 8e50f743d7bba80005c98fe8921dc2d1 587 SUPERFAMILY SSF51338 1 57 1.2E-22 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 BWK49_RS15450 8e50f743d7bba80005c98fe8921dc2d1 587 SUPERFAMILY SSF51338 498 523 1.2E-22 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 BWK49_RS15450 8e50f743d7bba80005c98fe8921dc2d1 587 Gene3D G3DSA:2.30.40.10 483 560 1.4E-12 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 BWK49_RS15450 8e50f743d7bba80005c98fe8921dc2d1 587 Gene3D G3DSA:3.20.20.140 420 482 2.9E-76 T 06-07-2017 BWK49_RS15450 8e50f743d7bba80005c98fe8921dc2d1 587 Gene3D G3DSA:3.20.20.140 71 308 2.9E-76 T 06-07-2017 BWK49_RS15450 8e50f743d7bba80005c98fe8921dc2d1 587 Gene3D G3DSA:2.30.40.10 3 70 3.3E-21 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 BWK49_RS15450 8e50f743d7bba80005c98fe8921dc2d1 587 SUPERFAMILY SSF51556 364 496 2.42E-37 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS15450 8e50f743d7bba80005c98fe8921dc2d1 587 SUPERFAMILY SSF51556 57 316 2.42E-37 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS06835 c4098c5c612e830f8d789d7858c73f8e 274 Pfam PF00296 Luciferase-like monooxygenase 20 208 6.9E-25 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS06835 c4098c5c612e830f8d789d7858c73f8e 274 TIGRFAM TIGR03621 F420_MSMEG_2516: probable F420-dependent oxidoreductase, MSMEG_2516 family 7 274 8.3E-109 T 06-07-2017 IPR019923 Luciferase-like, F420-dependent oxidoreductase, MSMEG2516, predicted BWK49_RS06835 c4098c5c612e830f8d789d7858c73f8e 274 Gene3D G3DSA:3.20.20.30 19 270 8.1E-39 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS06835 c4098c5c612e830f8d789d7858c73f8e 274 SUPERFAMILY SSF51679 14 266 1.13E-40 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS27415 479a0fec37cdd3047bed0d170b5c71e4 296 Pfam PF12697 Alpha/beta hydrolase family 32 284 1.1E-12 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS27415 479a0fec37cdd3047bed0d170b5c71e4 296 SUPERFAMILY SSF53474 223 295 3.88E-55 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS27415 479a0fec37cdd3047bed0d170b5c71e4 296 SUPERFAMILY SSF53474 3 144 3.88E-55 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS27415 479a0fec37cdd3047bed0d170b5c71e4 296 Gene3D G3DSA:3.40.50.1820 224 294 9.4E-59 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS27415 479a0fec37cdd3047bed0d170b5c71e4 296 Gene3D G3DSA:3.40.50.1820 3 139 9.4E-59 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS11420 4be3d596c364469ab9c45799f1dcc2d0 104 PIRSF PIRSF006909 1 102 4.9E-58 T 06-07-2017 IPR014447 Uncharacterised conserved protein UCP006909 BWK49_RS15700 764729ca4f41a3dc75689ae2117888ed 748 SUPERFAMILY SSF53706 12 629 6.54E-113 T 06-07-2017 BWK49_RS15700 764729ca4f41a3dc75689ae2117888ed 748 Gene3D G3DSA:2.40.40.20 599 735 2.3E-31 T 06-07-2017 BWK49_RS15700 764729ca4f41a3dc75689ae2117888ed 748 Gene3D G3DSA:2.20.25.90 11 64 1.3E-17 T 06-07-2017 BWK49_RS15700 764729ca4f41a3dc75689ae2117888ed 748 SMART SM00926 6 60 1.3E-14 T 06-07-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS15700 764729ca4f41a3dc75689ae2117888ed 748 SUPERFAMILY SSF50692 609 735 2.15E-33 T 06-07-2017 IPR009010 Aspartate decarboxylase-like domain BWK49_RS15700 764729ca4f41a3dc75689ae2117888ed 748 Gene3D G3DSA:3.40.50.740 65 167 3.0E-35 T 06-07-2017 BWK49_RS15700 764729ca4f41a3dc75689ae2117888ed 748 Gene3D G3DSA:3.40.50.740 372 486 3.0E-35 T 06-07-2017 BWK49_RS15700 764729ca4f41a3dc75689ae2117888ed 748 Gene3D G3DSA:3.40.228.10 168 356 8.0E-48 T 06-07-2017 BWK49_RS15700 764729ca4f41a3dc75689ae2117888ed 748 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 12 56 1.3E-11 T 06-07-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS15700 764729ca4f41a3dc75689ae2117888ed 748 Pfam PF00384 Molybdopterin oxidoreductase 63 486 6.7E-34 T 06-07-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS15700 764729ca4f41a3dc75689ae2117888ed 748 Pfam PF01568 Molydopterin dinucleotide binding domain 612 721 2.4E-25 T 06-07-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 BWK49_RS00065 239146d856bd98192ef1f3a2de2cefb9 180 Gene3D G3DSA:1.10.357.10 18 165 2.3E-19 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS00065 239146d856bd98192ef1f3a2de2cefb9 180 SUPERFAMILY SSF46689 12 83 2.14E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS00065 239146d856bd98192ef1f3a2de2cefb9 180 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 66 2.1E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS13080 e541311c93a5f5ba30568a75950af241 485 Gene3D G3DSA:3.90.190.20 437 480 1.2E-40 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 BWK49_RS13080 e541311c93a5f5ba30568a75950af241 485 Gene3D G3DSA:3.90.190.20 314 405 1.2E-40 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 BWK49_RS13080 e541311c93a5f5ba30568a75950af241 485 Gene3D G3DSA:3.40.1190.10 97 311 9.0E-58 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 BWK49_RS13080 e541311c93a5f5ba30568a75950af241 485 SUPERFAMILY SSF53623 114 310 3.14E-45 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 BWK49_RS13080 e541311c93a5f5ba30568a75950af241 485 SUPERFAMILY SSF51984 10 97 1.14E-11 T 06-07-2017 BWK49_RS13080 e541311c93a5f5ba30568a75950af241 485 Pfam PF02875 Mur ligase family, glutamate ligase domain 314 380 4.1E-10 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 BWK49_RS13080 e541311c93a5f5ba30568a75950af241 485 Gene3D G3DSA:3.40.50.720 11 96 2.1E-12 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS13080 e541311c93a5f5ba30568a75950af241 485 Pfam PF08245 Mur ligase middle domain 120 234 4.3E-20 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 BWK49_RS13080 e541311c93a5f5ba30568a75950af241 485 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 11 483 32.21 T 06-07-2017 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 BWK49_RS13080 e541311c93a5f5ba30568a75950af241 485 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 13 481 4.2E-135 T 06-07-2017 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 BWK49_RS13080 e541311c93a5f5ba30568a75950af241 485 SUPERFAMILY SSF53244 436 482 3.97E-30 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 BWK49_RS13080 e541311c93a5f5ba30568a75950af241 485 SUPERFAMILY SSF53244 314 399 3.97E-30 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 BWK49_RS15630 9922334fbf3f1618296b632df60a9d43 459 Pfam PF00487 Fatty acid desaturase 288 380 9.6E-17 T 06-07-2017 IPR005804 Fatty acid desaturase domain GO:0006629 BWK49_RS15630 9922334fbf3f1618296b632df60a9d43 459 Pfam PF00487 Fatty acid desaturase 66 219 1.2E-8 T 06-07-2017 IPR005804 Fatty acid desaturase domain GO:0006629 BWK49_RS03450 fcb8ef76742e694719c35038a4a346ff 261 SUPERFAMILY SSF56529 2 260 1.36E-75 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 BWK49_RS03450 fcb8ef76742e694719c35038a4a346ff 261 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 103 258 2.0E-10 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 BWK49_RS03450 fcb8ef76742e694719c35038a4a346ff 261 Gene3D G3DSA:3.90.850.10 5 260 2.1E-84 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 BWK49_RS00500 1a0bcc0ebcd8d6677e79bbe8815b280f 458 Gene3D G3DSA:3.20.20.30 2 315 2.4E-110 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS00500 1a0bcc0ebcd8d6677e79bbe8815b280f 458 Gene3D G3DSA:3.20.20.30 355 435 2.4E-110 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS00500 1a0bcc0ebcd8d6677e79bbe8815b280f 458 Pfam PF00296 Luciferase-like monooxygenase 22 391 4.0E-52 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS00500 1a0bcc0ebcd8d6677e79bbe8815b280f 458 PIRSF PIRSF000337 2 446 2.3E-111 T 06-07-2017 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 BWK49_RS00500 1a0bcc0ebcd8d6677e79bbe8815b280f 458 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 12 433 1.4E-136 T 06-07-2017 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 BWK49_RS00500 1a0bcc0ebcd8d6677e79bbe8815b280f 458 SUPERFAMILY SSF51679 1 435 1.31E-106 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS02725 12132f36100f479f2fffe33ee4006ff4 229 Gene3D G3DSA:1.10.10.10 174 225 8.3E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS02725 12132f36100f479f2fffe33ee4006ff4 229 Pfam PF03861 ANTAR domain 171 223 1.6E-18 T 06-07-2017 IPR005561 ANTAR domain GO:0003723 BWK49_RS02725 12132f36100f479f2fffe33ee4006ff4 229 Pfam PF13185 GAF domain 23 163 5.1E-13 T 06-07-2017 IPR003018 GAF domain GO:0005515 BWK49_RS02725 12132f36100f479f2fffe33ee4006ff4 229 SUPERFAMILY SSF55781 24 174 8.29E-19 T 06-07-2017 IPR029016 GAF domain-like BWK49_RS02725 12132f36100f479f2fffe33ee4006ff4 229 SUPERFAMILY SSF52172 167 223 8.95E-9 T 06-07-2017 IPR011006 CheY-like superfamily BWK49_RS02725 12132f36100f479f2fffe33ee4006ff4 229 Gene3D G3DSA:3.30.450.40 6 173 5.8E-16 T 06-07-2017 IPR029016 GAF domain-like BWK49_RS02725 12132f36100f479f2fffe33ee4006ff4 229 SMART SM01012 168 223 2.5E-21 T 06-07-2017 IPR005561 ANTAR domain GO:0003723 BWK49_RS02725 12132f36100f479f2fffe33ee4006ff4 229 PIRSF PIRSF036625 5 228 1.8E-57 T 06-07-2017 IPR012074 GAF-ANTAR transcription anti-termination regulator, putative BWK49_RS02725 12132f36100f479f2fffe33ee4006ff4 229 SMART SM00065 24 173 0.0084 T 06-07-2017 IPR003018 GAF domain GO:0005515 BWK49_RS04040 3fbe75d3c8f4c536b0bb35a531ed6783 777 PIRSF PIRSF001587 19 777 7.9E-281 T 06-07-2017 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 BWK49_RS04040 3fbe75d3c8f4c536b0bb35a531ed6783 777 Gene3D G3DSA:3.30.1330.10 74 222 8.6E-51 T 06-07-2017 IPR016188 PurM-like, N-terminal domain BWK49_RS04040 3fbe75d3c8f4c536b0bb35a531ed6783 777 Gene3D G3DSA:3.30.1330.10 453 600 5.0E-51 T 06-07-2017 IPR016188 PurM-like, N-terminal domain BWK49_RS04040 3fbe75d3c8f4c536b0bb35a531ed6783 777 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 1 777 309.851 T 06-07-2017 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 BWK49_RS04040 3fbe75d3c8f4c536b0bb35a531ed6783 777 SUPERFAMILY SSF56042 611 776 1.64E-37 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain BWK49_RS04040 3fbe75d3c8f4c536b0bb35a531ed6783 777 SUPERFAMILY SSF55326 38 223 4.64E-49 T 06-07-2017 BWK49_RS04040 3fbe75d3c8f4c536b0bb35a531ed6783 777 Pfam PF00586 AIR synthase related protein, N-terminal domain 116 217 6.1E-24 T 06-07-2017 IPR016188 PurM-like, N-terminal domain BWK49_RS04040 3fbe75d3c8f4c536b0bb35a531ed6783 777 Pfam PF00586 AIR synthase related protein, N-terminal domain 493 597 3.2E-22 T 06-07-2017 IPR016188 PurM-like, N-terminal domain BWK49_RS04040 3fbe75d3c8f4c536b0bb35a531ed6783 777 SUPERFAMILY SSF56042 230 464 1.14E-51 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain BWK49_RS04040 3fbe75d3c8f4c536b0bb35a531ed6783 777 Pfam PF02769 AIR synthase related protein, C-terminal domain 231 391 2.8E-34 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain BWK49_RS04040 3fbe75d3c8f4c536b0bb35a531ed6783 777 Pfam PF02769 AIR synthase related protein, C-terminal domain 611 748 1.3E-21 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain BWK49_RS04040 3fbe75d3c8f4c536b0bb35a531ed6783 777 SUPERFAMILY SSF55326 434 604 5.89E-53 T 06-07-2017 BWK49_RS04040 3fbe75d3c8f4c536b0bb35a531ed6783 777 TIGRFAM TIGR01736 FGAM_synth_II: phosphoribosylformylglycinamidine synthase II 42 774 4.5E-252 T 06-07-2017 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 BWK49_RS12300 7e6b659de2fd026dbfe6c015931abd39 1033 Pfam PF13091 PLD-like domain 139 268 8.3E-12 T 06-07-2017 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148 BWK49_RS12300 7e6b659de2fd026dbfe6c015931abd39 1033 Gene3D G3DSA:3.30.870.10 132 271 8.4E-9 T 06-07-2017 BWK49_RS12300 7e6b659de2fd026dbfe6c015931abd39 1033 SUPERFAMILY SSF56024 125 270 3.92E-9 T 06-07-2017 BWK49_RS12300 7e6b659de2fd026dbfe6c015931abd39 1033 Gene3D G3DSA:3.40.50.300 531 663 1.4E-22 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS12300 7e6b659de2fd026dbfe6c015931abd39 1033 Pfam PF11907 Domain of unknown function (DUF3427) 848 1025 2.0E-22 T 06-07-2017 IPR021835 Protein of unknown function DUF3427 BWK49_RS12300 7e6b659de2fd026dbfe6c015931abd39 1033 SMART SM00490 565 646 2.2E-12 T 06-07-2017 IPR001650 Helicase, C-terminal BWK49_RS12300 7e6b659de2fd026dbfe6c015931abd39 1033 SMART SM00487 308 493 5.2E-10 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain BWK49_RS12300 7e6b659de2fd026dbfe6c015931abd39 1033 Pfam PF04851 Type III restriction enzyme, res subunit 311 466 2.0E-29 T 06-07-2017 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 BWK49_RS12300 7e6b659de2fd026dbfe6c015931abd39 1033 SUPERFAMILY SSF52540 364 506 7.71E-40 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS12300 7e6b659de2fd026dbfe6c015931abd39 1033 SUPERFAMILY SSF52540 534 666 7.71E-40 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS12300 7e6b659de2fd026dbfe6c015931abd39 1033 Pfam PF00271 Helicase conserved C-terminal domain 555 644 8.3E-10 T 06-07-2017 IPR001650 Helicase, C-terminal BWK49_RS12300 7e6b659de2fd026dbfe6c015931abd39 1033 Gene3D G3DSA:3.40.50.300 310 470 5.3E-22 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS08340 74774611b3b24af16cab32bfacbaea8e 231 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 23 212 34.901 T 06-07-2017 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 BWK49_RS08340 74774611b3b24af16cab32bfacbaea8e 231 Pfam PF01583 Adenylylsulphate kinase 24 193 7.8E-65 T 06-07-2017 BWK49_RS08340 74774611b3b24af16cab32bfacbaea8e 231 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 7 207 2.3E-75 T 06-07-2017 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 BWK49_RS08340 74774611b3b24af16cab32bfacbaea8e 231 SUPERFAMILY SSF52540 19 210 6.13E-38 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS08340 74774611b3b24af16cab32bfacbaea8e 231 Gene3D G3DSA:3.40.50.300 2 215 1.2E-86 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS24830 0efd2d27ffcef846dc000813a8347b88 86 Pfam PF01381 Helix-turn-helix 30 79 2.1E-11 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 BWK49_RS24830 0efd2d27ffcef846dc000813a8347b88 86 SUPERFAMILY SSF47413 23 82 1.36E-13 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 BWK49_RS24830 0efd2d27ffcef846dc000813a8347b88 86 Gene3D G3DSA:1.10.260.40 27 82 1.9E-13 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 BWK49_RS24830 0efd2d27ffcef846dc000813a8347b88 86 SMART SM00530 27 82 1.0E-8 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 BWK49_RS26825 892b45f6592663d7da7431028222ee8b 308 Pfam PF03466 LysR substrate binding domain 87 291 6.2E-29 T 06-07-2017 IPR005119 LysR, substrate-binding BWK49_RS26825 892b45f6592663d7da7431028222ee8b 308 Gene3D G3DSA:3.40.190.10 194 263 5.9E-11 T 06-07-2017 BWK49_RS26825 892b45f6592663d7da7431028222ee8b 308 SUPERFAMILY SSF53850 88 293 2.71E-28 T 06-07-2017 BWK49_RS26825 892b45f6592663d7da7431028222ee8b 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.1E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 BWK49_RS26825 892b45f6592663d7da7431028222ee8b 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.1E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 BWK49_RS26825 892b45f6592663d7da7431028222ee8b 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.1E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 BWK49_RS26825 892b45f6592663d7da7431028222ee8b 308 Gene3D G3DSA:1.10.10.10 1 85 1.1E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS26825 892b45f6592663d7da7431028222ee8b 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 2.2E-19 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 BWK49_RS26825 892b45f6592663d7da7431028222ee8b 308 Gene3D G3DSA:3.40.190.10 88 193 2.6E-15 T 06-07-2017 BWK49_RS26825 892b45f6592663d7da7431028222ee8b 308 SUPERFAMILY SSF46785 1 86 2.12E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS27955 e5de4077b5be47b4d9a5322f75ff08f4 347 Gene3D G3DSA:3.40.50.720 165 285 6.2E-29 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS27955 e5de4077b5be47b4d9a5322f75ff08f4 347 Pfam PF00107 Zinc-binding dehydrogenase 171 303 2.9E-12 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 BWK49_RS27955 e5de4077b5be47b4d9a5322f75ff08f4 347 Gene3D G3DSA:3.90.180.10 5 164 3.4E-21 T 06-07-2017 IPR011032 GroES-like BWK49_RS27955 e5de4077b5be47b4d9a5322f75ff08f4 347 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 21 93 7.0E-10 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 BWK49_RS27955 e5de4077b5be47b4d9a5322f75ff08f4 347 SUPERFAMILY SSF51735 138 310 6.75E-27 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS27955 e5de4077b5be47b4d9a5322f75ff08f4 347 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 65 79 - T 06-07-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 BWK49_RS27955 e5de4077b5be47b4d9a5322f75ff08f4 347 SUPERFAMILY SSF50129 3 177 6.24E-26 T 06-07-2017 IPR011032 GroES-like BWK49_RS17300 0709c9659702ec19ae3ce3df691eb0c6 115 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 33 105 4.8E-33 T 06-07-2017 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 BWK49_RS17300 0709c9659702ec19ae3ce3df691eb0c6 115 SUPERFAMILY SSF141734 6 109 2.48E-44 T 06-07-2017 BWK49_RS17300 0709c9659702ec19ae3ce3df691eb0c6 115 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 7 110 30.462 T 06-07-2017 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 BWK49_RS17300 0709c9659702ec19ae3ce3df691eb0c6 115 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 56 110 3.0E-24 T 06-07-2017 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 BWK49_RS13435 bb87f2a531466ba2647b2321e1ddf24e 323 PIRSF PIRSF016838 1 323 1.6E-126 T 06-07-2017 IPR028349 Protein PafC BWK49_RS13435 bb87f2a531466ba2647b2321e1ddf24e 323 Pfam PF13280 WYL domain 148 314 1.7E-30 T 06-07-2017 IPR026881 WYL domain BWK49_RS06290 b01c66ee526a130338fae2631a156557 391 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 235 386 1.9E-14 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS06290 b01c66ee526a130338fae2631a156557 391 SUPERFAMILY SSF47203 235 390 4.67E-14 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS06290 b01c66ee526a130338fae2631a156557 391 SUPERFAMILY SSF56645 3 248 8.12E-73 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS06290 b01c66ee526a130338fae2631a156557 391 Gene3D G3DSA:1.20.140.10 225 390 1.7E-29 T 06-07-2017 BWK49_RS06290 b01c66ee526a130338fae2631a156557 391 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 129 141 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 BWK49_RS06290 b01c66ee526a130338fae2631a156557 391 Gene3D G3DSA:1.10.540.10 4 124 5.1E-22 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS06290 b01c66ee526a130338fae2631a156557 391 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 123 3.2E-17 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS06290 b01c66ee526a130338fae2631a156557 391 Gene3D G3DSA:2.40.110.10 127 224 2.2E-38 T 06-07-2017 BWK49_RS06290 b01c66ee526a130338fae2631a156557 391 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 127 223 4.8E-22 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 BWK49_RS08700 3863d5c8574536ea5b253a0933892d44 1288 SUPERFAMILY SSF141868 1034 1277 3.01E-73 T 06-07-2017 IPR001633 EAL domain BWK49_RS08700 3863d5c8574536ea5b253a0933892d44 1288 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 843 1005 3.3E-18 T 06-07-2017 IPR000160 GGDEF domain BWK49_RS08700 3863d5c8574536ea5b253a0933892d44 1288 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 311 468 2.8E-34 T 06-07-2017 IPR000160 GGDEF domain BWK49_RS08700 3863d5c8574536ea5b253a0933892d44 1288 SUPERFAMILY SSF55073 318 472 1.02E-42 T 06-07-2017 IPR029787 Nucleotide cyclase BWK49_RS08700 3863d5c8574536ea5b253a0933892d44 1288 SMART SM00052 1022 1267 4.8E-73 T 06-07-2017 IPR001633 EAL domain BWK49_RS08700 3863d5c8574536ea5b253a0933892d44 1288 SUPERFAMILY SSF55073 850 1007 9.42E-27 T 06-07-2017 IPR029787 Nucleotide cyclase BWK49_RS08700 3863d5c8574536ea5b253a0933892d44 1288 Pfam PF00563 EAL domain 1028 1259 2.1E-63 T 06-07-2017 IPR001633 EAL domain BWK49_RS08700 3863d5c8574536ea5b253a0933892d44 1288 SMART SM00267 833 1012 4.5E-22 T 06-07-2017 IPR000160 GGDEF domain BWK49_RS08700 3863d5c8574536ea5b253a0933892d44 1288 SMART SM00267 302 473 2.0E-56 T 06-07-2017 IPR000160 GGDEF domain BWK49_RS08700 3863d5c8574536ea5b253a0933892d44 1288 Gene3D G3DSA:3.30.70.270 847 1016 6.6E-35 T 06-07-2017 BWK49_RS08700 3863d5c8574536ea5b253a0933892d44 1288 Gene3D G3DSA:3.30.70.270 315 475 3.5E-49 T 06-07-2017 BWK49_RS08700 3863d5c8574536ea5b253a0933892d44 1288 Gene3D G3DSA:3.20.20.450 1026 1275 1.5E-79 T 06-07-2017 IPR001633 EAL domain BWK49_RS08700 3863d5c8574536ea5b253a0933892d44 1288 Pfam PF00990 Diguanylate cyclase, GGDEF domain 845 1005 1.8E-26 T 06-07-2017 IPR000160 GGDEF domain BWK49_RS08700 3863d5c8574536ea5b253a0933892d44 1288 Pfam PF00990 Diguanylate cyclase, GGDEF domain 313 467 3.7E-39 T 06-07-2017 IPR000160 GGDEF domain BWK49_RS11545 80ac30166b47ec483314fb5444366f8a 461 SUPERFAMILY SSF51679 9 445 4.58E-119 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS11545 80ac30166b47ec483314fb5444366f8a 461 Gene3D G3DSA:3.20.20.30 362 445 3.3E-125 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS11545 80ac30166b47ec483314fb5444366f8a 461 Gene3D G3DSA:3.20.20.30 8 312 3.3E-125 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS11545 80ac30166b47ec483314fb5444366f8a 461 Pfam PF00296 Luciferase-like monooxygenase 30 395 2.4E-58 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS11545 80ac30166b47ec483314fb5444366f8a 461 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 22 441 1.1E-134 T 06-07-2017 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 BWK49_RS11545 80ac30166b47ec483314fb5444366f8a 461 PIRSF PIRSF000337 7 452 3.9E-149 T 06-07-2017 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 BWK49_RS07095 8011b663039affbe413303ce931febe9 165 SMART SM00852 12 156 1.5E-17 T 06-07-2017 IPR001453 MoaB/Mog domain BWK49_RS07095 8011b663039affbe413303ce931febe9 165 SUPERFAMILY SSF53218 11 161 7.72E-32 T 06-07-2017 IPR001453 MoaB/Mog domain BWK49_RS07095 8011b663039affbe413303ce931febe9 165 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 11 149 1.1E-29 T 06-07-2017 IPR001453 MoaB/Mog domain BWK49_RS07095 8011b663039affbe413303ce931febe9 165 Pfam PF00994 Probable molybdopterin binding domain 14 151 1.6E-24 T 06-07-2017 IPR001453 MoaB/Mog domain BWK49_RS07095 8011b663039affbe413303ce931febe9 165 Gene3D G3DSA:3.40.980.10 11 161 2.7E-37 T 06-07-2017 IPR001453 MoaB/Mog domain BWK49_RS00400 774c19109568a4672e0d935542956bf4 229 SUPERFAMILY SSF46689 34 97 1.47E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS00400 774c19109568a4672e0d935542956bf4 229 Pfam PF16859 Bacterial transcriptional repressor C-terminal 101 210 9.9E-22 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS00400 774c19109568a4672e0d935542956bf4 229 Pfam PF00440 Bacterial regulatory proteins, tetR family 41 84 2.1E-16 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS00400 774c19109568a4672e0d935542956bf4 229 SUPERFAMILY SSF48498 104 214 5.93E-16 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS00400 774c19109568a4672e0d935542956bf4 229 Gene3D G3DSA:1.10.10.60 35 78 2.5E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS00400 774c19109568a4672e0d935542956bf4 229 Gene3D G3DSA:1.10.357.10 80 215 4.5E-21 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS00400 774c19109568a4672e0d935542956bf4 229 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 62 85 2.3E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS00400 774c19109568a4672e0d935542956bf4 229 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 54 2.3E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS00300 7cd835c0e796a5ce4acb3e509579e4b1 396 SUPERFAMILY SSF51395 6 262 4.79E-86 T 06-07-2017 BWK49_RS00300 7cd835c0e796a5ce4acb3e509579e4b1 396 SUPERFAMILY SSF51395 296 382 4.79E-86 T 06-07-2017 BWK49_RS00300 7cd835c0e796a5ce4acb3e509579e4b1 396 Gene3D G3DSA:3.20.20.70 7 383 1.3E-90 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 BWK49_RS00300 7cd835c0e796a5ce4acb3e509579e4b1 396 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 7 228 1.1E-40 T 06-07-2017 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 BWK49_RS19160 9eae0114c984f69deac5ed896b9fd573 404 Pfam PF04909 Amidohydrolase 46 361 1.7E-33 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 BWK49_RS19160 9eae0114c984f69deac5ed896b9fd573 404 SUPERFAMILY SSF51556 4 362 2.68E-65 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS19160 9eae0114c984f69deac5ed896b9fd573 404 Gene3D G3DSA:3.20.20.140 47 365 1.5E-60 T 06-07-2017 BWK49_RS09510 afeeb91b7f2940b5e614425206d9dd05 368 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 224 363 3.7E-22 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS09510 afeeb91b7f2940b5e614425206d9dd05 368 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 12 113 8.4E-10 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS09510 afeeb91b7f2940b5e614425206d9dd05 368 SUPERFAMILY SSF47203 224 365 2.9E-12 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS09510 afeeb91b7f2940b5e614425206d9dd05 368 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 119 131 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 BWK49_RS09510 afeeb91b7f2940b5e614425206d9dd05 368 Gene3D G3DSA:2.40.110.10 116 213 2.5E-35 T 06-07-2017 BWK49_RS09510 afeeb91b7f2940b5e614425206d9dd05 368 SUPERFAMILY SSF56645 8 237 1.57E-61 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS09510 afeeb91b7f2940b5e614425206d9dd05 368 Gene3D G3DSA:1.10.540.10 6 113 8.2E-14 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS09510 afeeb91b7f2940b5e614425206d9dd05 368 Gene3D G3DSA:1.20.140.10 214 367 5.7E-24 T 06-07-2017 BWK49_RS09510 afeeb91b7f2940b5e614425206d9dd05 368 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 117 212 1.6E-21 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 BWK49_RS20585 16aee06b38199e1cae087c65f9deced8 74 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 1 64 1.4E-27 T 06-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 BWK49_RS20585 16aee06b38199e1cae087c65f9deced8 74 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 35 41 - T 06-07-2017 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 BWK49_RS20585 16aee06b38199e1cae087c65f9deced8 74 Gene3D G3DSA:1.10.10.10 1 67 7.3E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS20585 16aee06b38199e1cae087c65f9deced8 74 SUPERFAMILY SSF46767 1 66 4.97E-25 T 06-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 BWK49_RS20585 16aee06b38199e1cae087c65f9deced8 74 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 1 66 1.7E-26 T 06-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 BWK49_RS15665 da3ebb0bc514c5af78103967a8133128 151 Pfam PF01575 MaoC like domain 20 114 3.3E-7 T 06-07-2017 IPR002539 MaoC-like domain BWK49_RS15665 da3ebb0bc514c5af78103967a8133128 151 Gene3D G3DSA:3.10.129.10 3 148 1.2E-24 T 06-07-2017 IPR029069 HotDog domain BWK49_RS15665 da3ebb0bc514c5af78103967a8133128 151 SUPERFAMILY SSF54637 5 149 4.81E-28 T 06-07-2017 IPR029069 HotDog domain BWK49_RS24930 2ebbd8cdcad5fb2c5531aa791ce3eb50 268 Pfam PF00561 alpha/beta hydrolase fold 10 255 6.3E-13 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS24930 2ebbd8cdcad5fb2c5531aa791ce3eb50 268 SUPERFAMILY SSF53474 6 267 1.54E-36 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS24930 2ebbd8cdcad5fb2c5531aa791ce3eb50 268 Gene3D G3DSA:3.40.50.1820 4 268 1.8E-39 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS24930 2ebbd8cdcad5fb2c5531aa791ce3eb50 268 PRINTS PR00412 Epoxide hydrolase signature 13 31 8.0E-15 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS24930 2ebbd8cdcad5fb2c5531aa791ce3eb50 268 PRINTS PR00412 Epoxide hydrolase signature 33 48 8.0E-15 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS24930 2ebbd8cdcad5fb2c5531aa791ce3eb50 268 PRINTS PR00412 Epoxide hydrolase signature 76 89 8.0E-15 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS24930 2ebbd8cdcad5fb2c5531aa791ce3eb50 268 PRINTS PR00412 Epoxide hydrolase signature 243 265 8.0E-15 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS27010 83f93c654cbbdbcbec1a622bad89829d 338 SUPERFAMILY SSF54637 13 160 5.39E-29 T 06-07-2017 IPR029069 HotDog domain BWK49_RS27010 83f93c654cbbdbcbec1a622bad89829d 338 SUPERFAMILY SSF54637 189 336 2.27E-30 T 06-07-2017 IPR029069 HotDog domain BWK49_RS27010 83f93c654cbbdbcbec1a622bad89829d 338 PIRSF PIRSF021494 7 338 2.4E-139 T 06-07-2017 IPR016790 Thiol ester hydratase, Rv0216, predicted KEGG: 00630+4.2.1.148|KEGG: 00660+4.2.1.148|KEGG: 00720+4.2.1.148|MetaCyc: PWY-5741|MetaCyc: PWY-5744|MetaCyc: PWY-6728 BWK49_RS27010 83f93c654cbbdbcbec1a622bad89829d 338 Gene3D G3DSA:3.10.129.10 11 158 2.3E-18 T 06-07-2017 IPR029069 HotDog domain BWK49_RS27010 83f93c654cbbdbcbec1a622bad89829d 338 Gene3D G3DSA:3.10.129.10 202 311 5.4E-11 T 06-07-2017 IPR029069 HotDog domain BWK49_RS26885 d5e1b47bafce21846b64c42bce2d7099 326 SUPERFAMILY SSF51556 4 320 2.36E-87 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS26885 d5e1b47bafce21846b64c42bce2d7099 326 Pfam PF02126 Phosphotriesterase family 11 320 1.4E-135 T 06-07-2017 IPR001559 Phosphotriesterase GO:0008270|GO:0009056 BWK49_RS26885 d5e1b47bafce21846b64c42bce2d7099 326 ProSitePatterns PS01322 Phosphotriesterase family signature 1. 17 25 - T 06-07-2017 IPR017947 Aryldialkylphosphatase, zinc-binding site GO:0008270|GO:0009056|GO:0016788 BWK49_RS26885 d5e1b47bafce21846b64c42bce2d7099 326 Gene3D G3DSA:3.20.20.140 4 321 2.5E-114 T 06-07-2017 BWK49_RS02625 f69a32e9102eb3b133b20e13bca64dd4 379 Pfam PF14258 Domain of unknown function (DUF4350) 52 109 3.7E-8 T 06-07-2017 IPR025646 Domain of unknown function DUF4350 BWK49_RS07475 80f6aef48bcd2519c854dbc34d749f5d 493 SUPERFAMILY SSF51161 261 475 1.45E-42 T 06-07-2017 IPR011004 Trimeric LpxA-like BWK49_RS07475 80f6aef48bcd2519c854dbc34d749f5d 493 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 8 465 2.0E-175 T 06-07-2017 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 BWK49_RS07475 80f6aef48bcd2519c854dbc34d749f5d 493 Gene3D G3DSA:3.90.550.10 5 261 6.1E-71 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases BWK49_RS07475 80f6aef48bcd2519c854dbc34d749f5d 493 Gene3D G3DSA:2.160.10.10 268 449 8.4E-40 T 06-07-2017 BWK49_RS07475 80f6aef48bcd2519c854dbc34d749f5d 493 SUPERFAMILY SSF53448 8 264 1.71E-59 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases BWK49_RS07475 80f6aef48bcd2519c854dbc34d749f5d 493 Pfam PF12804 MobA-like NTP transferase domain 9 142 2.3E-20 T 06-07-2017 IPR025877 MobA-like NTP transferase BWK49_RS07475 80f6aef48bcd2519c854dbc34d749f5d 493 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 277 311 4.0E-5 T 06-07-2017 IPR001451 Hexapeptide repeat BWK49_RS07475 80f6aef48bcd2519c854dbc34d749f5d 493 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 328 360 7.9E-5 T 06-07-2017 IPR001451 Hexapeptide repeat BWK49_RS07475 80f6aef48bcd2519c854dbc34d749f5d 493 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 406 440 1.8E-5 T 06-07-2017 IPR001451 Hexapeptide repeat BWK49_RS07475 80f6aef48bcd2519c854dbc34d749f5d 493 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 6 463 38.657 T 06-07-2017 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 BWK49_RS24745 6a832fbe9dd3543957a43d2dfa0ab451 363 PRINTS PR00473 Galactokinase signature 91 109 9.1E-22 T 06-07-2017 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 BWK49_RS24745 6a832fbe9dd3543957a43d2dfa0ab451 363 PRINTS PR00473 Galactokinase signature 71 82 9.1E-22 T 06-07-2017 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 BWK49_RS24745 6a832fbe9dd3543957a43d2dfa0ab451 363 PRINTS PR00473 Galactokinase signature 245 259 9.1E-22 T 06-07-2017 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 BWK49_RS24745 6a832fbe9dd3543957a43d2dfa0ab451 363 PRINTS PR00473 Galactokinase signature 9 27 9.1E-22 T 06-07-2017 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 BWK49_RS24745 6a832fbe9dd3543957a43d2dfa0ab451 363 Pfam PF00288 GHMP kinases N terminal domain 94 160 1.4E-13 T 06-07-2017 IPR006204 GHMP kinase N-terminal domain GO:0005524 BWK49_RS24745 6a832fbe9dd3543957a43d2dfa0ab451 363 SUPERFAMILY SSF55060 187 360 1.5E-43 T 06-07-2017 IPR013750 GHMP kinase, C-terminal domain BWK49_RS24745 6a832fbe9dd3543957a43d2dfa0ab451 363 PRINTS PR00959 Mevalonate kinase family signature 308 325 2.7E-39 T 06-07-2017 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 BWK49_RS24745 6a832fbe9dd3543957a43d2dfa0ab451 363 PRINTS PR00959 Mevalonate kinase family signature 98 120 2.7E-39 T 06-07-2017 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 BWK49_RS24745 6a832fbe9dd3543957a43d2dfa0ab451 363 PRINTS PR00959 Mevalonate kinase family signature 141 160 2.7E-39 T 06-07-2017 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 BWK49_RS24745 6a832fbe9dd3543957a43d2dfa0ab451 363 PRINTS PR00959 Mevalonate kinase family signature 7 31 2.7E-39 T 06-07-2017 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 BWK49_RS24745 6a832fbe9dd3543957a43d2dfa0ab451 363 ProSitePatterns PS00106 Galactokinase signature. 9 20 - T 06-07-2017 IPR019741 Galactokinase, conserved site KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 BWK49_RS24745 6a832fbe9dd3543957a43d2dfa0ab451 363 Gene3D G3DSA:3.30.230.10 6 190 5.9E-58 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup BWK49_RS24745 6a832fbe9dd3543957a43d2dfa0ab451 363 Pfam PF10509 Galactokinase galactose-binding signature 7 38 1.1E-14 T 06-07-2017 IPR019539 Galactokinase galactose-binding domain KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 BWK49_RS24745 6a832fbe9dd3543957a43d2dfa0ab451 363 Gene3D G3DSA:3.30.70.890 191 360 4.9E-48 T 06-07-2017 IPR013750 GHMP kinase, C-terminal domain BWK49_RS24745 6a832fbe9dd3543957a43d2dfa0ab451 363 PIRSF PIRSF000530 2 363 1.1E-100 T 06-07-2017 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 BWK49_RS24745 6a832fbe9dd3543957a43d2dfa0ab451 363 Pfam PF08544 GHMP kinases C terminal 262 339 9.6E-11 T 06-07-2017 IPR013750 GHMP kinase, C-terminal domain BWK49_RS24745 6a832fbe9dd3543957a43d2dfa0ab451 363 SUPERFAMILY SSF54211 3 182 1.21E-47 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold BWK49_RS24745 6a832fbe9dd3543957a43d2dfa0ab451 363 TIGRFAM TIGR00131 gal_kin: galactokinase 5 343 3.3E-77 T 06-07-2017 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 BWK49_RS15805 b4171503bb0d95506b6e9235b81f522a 532 Gene3D G3DSA:3.40.50.980 201 342 4.3E-38 T 06-07-2017 BWK49_RS15805 b4171503bb0d95506b6e9235b81f522a 532 Gene3D G3DSA:3.30.300.30 425 523 2.2E-32 T 06-07-2017 BWK49_RS15805 b4171503bb0d95506b6e9235b81f522a 532 Pfam PF13193 AMP-binding enzyme C-terminal domain 439 514 6.5E-23 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS15805 b4171503bb0d95506b6e9235b81f522a 532 Gene3D G3DSA:3.40.50.980 23 132 7.5E-30 T 06-07-2017 BWK49_RS15805 b4171503bb0d95506b6e9235b81f522a 532 Gene3D G3DSA:3.40.50.980 168 200 7.5E-30 T 06-07-2017 BWK49_RS15805 b4171503bb0d95506b6e9235b81f522a 532 Gene3D G3DSA:2.30.38.10 349 424 3.7E-23 T 06-07-2017 BWK49_RS15805 b4171503bb0d95506b6e9235b81f522a 532 Pfam PF00501 AMP-binding enzyme 27 430 2.5E-95 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS15805 b4171503bb0d95506b6e9235b81f522a 532 ProSitePatterns PS00455 Putative AMP-binding domain signature. 183 194 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS15805 b4171503bb0d95506b6e9235b81f522a 532 SUPERFAMILY SSF56801 20 524 4.97E-151 T 06-07-2017 BWK49_RS02760 13132351cbb195809c99b7dab59bf465 339 SUPERFAMILY SSF52540 22 243 3.51E-25 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS02760 13132351cbb195809c99b7dab59bf465 339 Pfam PF02374 Anion-transporting ATPase 22 180 2.9E-17 T 06-07-2017 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 BWK49_RS02760 13132351cbb195809c99b7dab59bf465 339 Gene3D G3DSA:3.40.50.300 19 243 2.9E-30 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS08805 e3d2c3548ad41d8ca52d456170097045 309 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 40 262 1.3E-48 T 06-07-2017 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 BWK49_RS08805 e3d2c3548ad41d8ca52d456170097045 309 SUPERFAMILY SSF52402 14 216 1.19E-65 T 06-07-2017 BWK49_RS08805 e3d2c3548ad41d8ca52d456170097045 309 TIGRFAM TIGR02039 CysD: sulfate adenylyltransferase, small subunit 19 309 5.4E-146 T 06-07-2017 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 BWK49_RS08805 e3d2c3548ad41d8ca52d456170097045 309 Gene3D G3DSA:3.40.50.620 5 217 3.0E-51 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold BWK49_RS08805 e3d2c3548ad41d8ca52d456170097045 309 Gene3D G3DSA:3.40.50.620 250 257 3.0E-51 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold BWK49_RS08805 e3d2c3548ad41d8ca52d456170097045 309 Hamap MF_00064 Sulfate adenylyltransferase subunit 2 [cysD]. 14 309 54.389 T 06-07-2017 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 BWK49_RS08805 e3d2c3548ad41d8ca52d456170097045 309 PIRSF PIRSF002936 10 309 9.4E-140 T 06-07-2017 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 BWK49_RS17135 26e8d1fca8cb94d38c42d7667a59f9b4 213 Gene3D G3DSA:3.40.50.180 10 193 1.0E-41 T 06-07-2017 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 BWK49_RS17135 26e8d1fca8cb94d38c42d7667a59f9b4 213 SUPERFAMILY SSF52738 13 193 7.72E-35 T 06-07-2017 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 BWK49_RS17135 26e8d1fca8cb94d38c42d7667a59f9b4 213 Pfam PF01339 CheB methylesterase 16 188 7.9E-39 T 06-07-2017 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 BWK49_RS08105 4fc7baeaf740fe75fd595f5d57572957 494 SUPERFAMILY SSF53720 9 492 2.09E-139 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 BWK49_RS08105 4fc7baeaf740fe75fd595f5d57572957 494 Pfam PF00171 Aldehyde dehydrogenase family 20 489 9.7E-143 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 BWK49_RS08105 4fc7baeaf740fe75fd595f5d57572957 494 Gene3D G3DSA:3.40.605.10 12 274 4.3E-69 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 BWK49_RS08105 4fc7baeaf740fe75fd595f5d57572957 494 Gene3D G3DSA:3.40.309.10 275 464 2.8E-58 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 BWK49_RS08105 4fc7baeaf740fe75fd595f5d57572957 494 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 263 270 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 BWK49_RS24905 186b625b72d871288245a29d5f367bf3 241 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2 170 4.4E-5 T 06-07-2017 BWK49_RS24905 186b625b72d871288245a29d5f367bf3 241 Gene3D G3DSA:3.40.50.720 2 199 1.8E-54 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS24905 186b625b72d871288245a29d5f367bf3 241 SUPERFAMILY SSF51735 3 203 1.89E-54 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS24905 186b625b72d871288245a29d5f367bf3 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 158 8.6E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS24905 186b625b72d871288245a29d5f367bf3 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 68 79 8.6E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS24905 186b625b72d871288245a29d5f367bf3 241 Pfam PF00106 short chain dehydrogenase 3 180 1.5E-43 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS24905 186b625b72d871288245a29d5f367bf3 241 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 126 154 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS24905 186b625b72d871288245a29d5f367bf3 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 177 4.5E-21 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS24905 186b625b72d871288245a29d5f367bf3 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 4.5E-21 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS24905 186b625b72d871288245a29d5f367bf3 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 139 158 4.5E-21 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS24905 186b625b72d871288245a29d5f367bf3 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 68 79 4.5E-21 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS10755 b9428b1a85bdfbf6d7d010f947ac7ae9 88 SUPERFAMILY SSF56281 4 48 2.57E-6 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS10755 b9428b1a85bdfbf6d7d010f947ac7ae9 88 Gene3D G3DSA:3.60.15.10 4 48 1.3E-5 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS21840 113fde314dcd302f4e725a0ea14b1330 314 SUPERFAMILY SSF82689 188 283 1.14E-7 T 06-07-2017 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 BWK49_RS21840 113fde314dcd302f4e725a0ea14b1330 314 Gene3D G3DSA:2.30.30.60 135 186 2.2E-13 T 06-07-2017 BWK49_RS21840 113fde314dcd302f4e725a0ea14b1330 314 SUPERFAMILY SSF50182 120 183 8.83E-12 T 06-07-2017 IPR010920 LSM domain BWK49_RS21840 113fde314dcd302f4e725a0ea14b1330 314 Pfam PF00924 Mechanosensitive ion channel 78 280 6.4E-40 T 06-07-2017 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 BWK49_RS08740 937a82bd3c07ec62cc356e275ffd8005 588 Pfam PF00005 ABC transporter 352 502 3.9E-26 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 BWK49_RS08740 937a82bd3c07ec62cc356e275ffd8005 588 Gene3D G3DSA:1.20.1560.10 6 321 2.1E-59 T 06-07-2017 BWK49_RS08740 937a82bd3c07ec62cc356e275ffd8005 588 SMART SM00382 361 550 1.2E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS08740 937a82bd3c07ec62cc356e275ffd8005 588 Pfam PF00664 ABC transporter transmembrane region 19 288 2.4E-48 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 BWK49_RS08740 937a82bd3c07ec62cc356e275ffd8005 588 Gene3D G3DSA:3.40.50.300 334 568 1.2E-68 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS08740 937a82bd3c07ec62cc356e275ffd8005 588 ProSitePatterns PS00211 ABC transporters family signature. 476 490 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 BWK49_RS08740 937a82bd3c07ec62cc356e275ffd8005 588 SUPERFAMILY SSF52540 329 574 4.52E-78 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS08740 937a82bd3c07ec62cc356e275ffd8005 588 SUPERFAMILY SSF90123 6 322 1.29E-67 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 BWK49_RS05875 a890b5c5f7e18e93cc7bdea0e15ad589 406 SMART SM00387 310 406 8.9E-4 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS05875 a890b5c5f7e18e93cc7bdea0e15ad589 406 Gene3D G3DSA:3.30.565.10 283 404 5.2E-6 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS05875 a890b5c5f7e18e93cc7bdea0e15ad589 406 SUPERFAMILY SSF55874 269 404 5.11E-13 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS22925 c888f4f23942be0549d23cb2356e3c86 567 PRINTS PR00344 Bacterial sensor protein C-terminal signature 444 458 4.5E-12 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 BWK49_RS22925 c888f4f23942be0549d23cb2356e3c86 567 PRINTS PR00344 Bacterial sensor protein C-terminal signature 479 497 4.5E-12 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 BWK49_RS22925 c888f4f23942be0549d23cb2356e3c86 567 PRINTS PR00344 Bacterial sensor protein C-terminal signature 462 472 4.5E-12 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 BWK49_RS22925 c888f4f23942be0549d23cb2356e3c86 567 PRINTS PR00344 Bacterial sensor protein C-terminal signature 503 516 4.5E-12 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 BWK49_RS22925 c888f4f23942be0549d23cb2356e3c86 567 Pfam PF00512 His Kinase A (phospho-acceptor) domain 296 362 4.7E-16 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 BWK49_RS22925 c888f4f23942be0549d23cb2356e3c86 567 Gene3D G3DSA:1.10.287.130 286 358 5.7E-16 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 BWK49_RS22925 c888f4f23942be0549d23cb2356e3c86 567 Pfam PF00672 HAMP domain 216 283 5.5E-12 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 BWK49_RS22925 c888f4f23942be0549d23cb2356e3c86 567 SMART SM00304 235 287 3.4E-11 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 BWK49_RS22925 c888f4f23942be0549d23cb2356e3c86 567 SUPERFAMILY SSF55874 351 521 1.96E-41 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS22925 c888f4f23942be0549d23cb2356e3c86 567 SUPERFAMILY SSF47384 278 362 1.28E-17 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 BWK49_RS22925 c888f4f23942be0549d23cb2356e3c86 567 SUPERFAMILY SSF158472 235 285 1.31E-8 T 06-07-2017 BWK49_RS22925 c888f4f23942be0549d23cb2356e3c86 567 Gene3D G3DSA:3.30.565.10 365 519 6.2E-39 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS22925 c888f4f23942be0549d23cb2356e3c86 567 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 409 517 6.0E-19 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS22925 c888f4f23942be0549d23cb2356e3c86 567 SMART SM00387 408 519 1.8E-29 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS22925 c888f4f23942be0549d23cb2356e3c86 567 SMART SM00388 295 362 9.5E-18 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 BWK49_RS06975 b974e01600c76e0932f3ca32f0202c79 387 Gene3D G3DSA:3.30.470.20 88 229 1.6E-50 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 BWK49_RS06975 b974e01600c76e0932f3ca32f0202c79 387 Pfam PF00549 CoA-ligase 256 368 9.7E-14 T 06-07-2017 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 BWK49_RS06975 b974e01600c76e0932f3ca32f0202c79 387 Gene3D G3DSA:3.30.1490.20 22 87 4.1E-16 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 BWK49_RS06975 b974e01600c76e0932f3ca32f0202c79 387 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 1 385 1.6E-121 T 06-07-2017 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 BWK49_RS06975 b974e01600c76e0932f3ca32f0202c79 387 SUPERFAMILY SSF52210 231 385 5.63E-41 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 BWK49_RS06975 b974e01600c76e0932f3ca32f0202c79 387 Gene3D G3DSA:3.40.50.261 232 385 8.4E-53 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 BWK49_RS06975 b974e01600c76e0932f3ca32f0202c79 387 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 249 273 - T 06-07-2017 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 BWK49_RS06975 b974e01600c76e0932f3ca32f0202c79 387 Hamap MF_00558 Succinyl-CoA ligase [ADP-forming] subunit beta [sucC]. 1 386 39.78 T 06-07-2017 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 BWK49_RS06975 b974e01600c76e0932f3ca32f0202c79 387 SUPERFAMILY SSF56059 1 226 1.77E-63 T 06-07-2017 BWK49_RS06975 b974e01600c76e0932f3ca32f0202c79 387 Pfam PF08442 ATP-grasp domain 2 194 2.8E-70 T 06-07-2017 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 BWK49_RS06975 b974e01600c76e0932f3ca32f0202c79 387 PIRSF PIRSF001554 1 387 4.7E-134 T 06-07-2017 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 BWK49_RS13640 e2ca1b012a079336b98254e3e42a6038 349 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 10 74 3.9E-6 T 06-07-2017 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 BWK49_RS13640 e2ca1b012a079336b98254e3e42a6038 349 SUPERFAMILY SSF51735 3 148 1.32E-14 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS13640 e2ca1b012a079336b98254e3e42a6038 349 Gene3D G3DSA:3.40.50.720 5 158 8.7E-26 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS21025 88e4b34233208938c2490a95fc83fb04 203 SUPERFAMILY SSF46689 21 78 3.23E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS21025 88e4b34233208938c2490a95fc83fb04 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 3.6E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS21025 88e4b34233208938c2490a95fc83fb04 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 38 3.6E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS21025 88e4b34233208938c2490a95fc83fb04 203 Gene3D G3DSA:1.10.10.60 17 67 2.2E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS21025 88e4b34233208938c2490a95fc83fb04 203 Pfam PF16859 Bacterial transcriptional repressor C-terminal 82 190 1.8E-26 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS21025 88e4b34233208938c2490a95fc83fb04 203 SUPERFAMILY SSF48498 86 195 1.17E-20 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS21025 88e4b34233208938c2490a95fc83fb04 203 Gene3D G3DSA:1.10.357.10 68 193 1.6E-30 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS21025 88e4b34233208938c2490a95fc83fb04 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 71 9.9E-15 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS09180 474c234312c0189a8ad747b825b49b5b 359 Gene3D G3DSA:3.90.1200.10 141 350 3.4E-24 T 06-07-2017 BWK49_RS09180 474c234312c0189a8ad747b825b49b5b 359 SUPERFAMILY SSF56112 16 331 4.81E-27 T 06-07-2017 IPR011009 Protein kinase-like domain BWK49_RS09180 474c234312c0189a8ad747b825b49b5b 359 Pfam PF01636 Phosphotransferase enzyme family 99 291 1.4E-14 T 06-07-2017 IPR002575 Aminoglycoside phosphotransferase BWK49_RS19105 31f0558255ad70e0e8b5b205791fc636 276 Gene3D G3DSA:3.90.226.10 21 262 2.3E-57 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS19105 31f0558255ad70e0e8b5b205791fc636 276 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 117 137 - T 06-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 BWK49_RS19105 31f0558255ad70e0e8b5b205791fc636 276 SUPERFAMILY SSF52096 17 265 1.77E-61 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS19105 31f0558255ad70e0e8b5b205791fc636 276 Pfam PF00378 Enoyl-CoA hydratase/isomerase 26 266 4.0E-41 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 BWK49_RS25745 1e0124adefb1fb7c9fc36c1d1a888b4b 268 SUPERFAMILY SSF56219 1 266 1.15E-71 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase BWK49_RS25745 1e0124adefb1fb7c9fc36c1d1a888b4b 268 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 1 264 1.2E-56 T 06-07-2017 BWK49_RS25745 1e0124adefb1fb7c9fc36c1d1a888b4b 268 Gene3D G3DSA:3.60.10.10 1 266 1.4E-78 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase BWK49_RS25745 1e0124adefb1fb7c9fc36c1d1a888b4b 268 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 4 258 1.0E-22 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase BWK49_RS25745 1e0124adefb1fb7c9fc36c1d1a888b4b 268 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 265 5.2E-80 T 06-07-2017 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 BWK49_RS10645 2ee0f08b63266c496a6a71511d0fbd8f 340 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 2 303 3.5E-61 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme BWK49_RS10645 2ee0f08b63266c496a6a71511d0fbd8f 340 SUPERFAMILY SSF53686 2 311 4.45E-64 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme BWK49_RS10645 2ee0f08b63266c496a6a71511d0fbd8f 340 Gene3D G3DSA:3.40.50.1100 72 313 4.8E-41 T 06-07-2017 BWK49_RS07370 d35510d253cc2a2a9ba660867d793d4e 236 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 3.4E-12 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS07370 d35510d253cc2a2a9ba660867d793d4e 236 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 3.4E-12 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS07370 d35510d253cc2a2a9ba660867d793d4e 236 SUPERFAMILY SSF48498 81 217 3.89E-22 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS07370 d35510d253cc2a2a9ba660867d793d4e 236 SUPERFAMILY SSF46689 1 82 9.23E-20 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS07370 d35510d253cc2a2a9ba660867d793d4e 236 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 57 3.9E-16 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS07370 d35510d253cc2a2a9ba660867d793d4e 236 Gene3D G3DSA:1.10.357.10 1 200 2.5E-36 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS25365 47cd65b2ba4b3a2d477bdd8a14151708 409 SMART SM00388 156 222 3.4E-17 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 BWK49_RS25365 47cd65b2ba4b3a2d477bdd8a14151708 409 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 267 378 4.5E-23 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS25365 47cd65b2ba4b3a2d477bdd8a14151708 409 PRINTS PR00344 Bacterial sensor protein C-terminal signature 363 376 8.1E-19 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 BWK49_RS25365 47cd65b2ba4b3a2d477bdd8a14151708 409 PRINTS PR00344 Bacterial sensor protein C-terminal signature 304 318 8.1E-19 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 BWK49_RS25365 47cd65b2ba4b3a2d477bdd8a14151708 409 PRINTS PR00344 Bacterial sensor protein C-terminal signature 322 332 8.1E-19 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 BWK49_RS25365 47cd65b2ba4b3a2d477bdd8a14151708 409 PRINTS PR00344 Bacterial sensor protein C-terminal signature 339 357 8.1E-19 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 BWK49_RS25365 47cd65b2ba4b3a2d477bdd8a14151708 409 SUPERFAMILY SSF47384 140 220 4.51E-15 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 BWK49_RS25365 47cd65b2ba4b3a2d477bdd8a14151708 409 Gene3D G3DSA:1.10.287.130 151 208 4.8E-14 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 BWK49_RS25365 47cd65b2ba4b3a2d477bdd8a14151708 409 Gene3D G3DSA:3.30.565.10 209 380 3.5E-45 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS25365 47cd65b2ba4b3a2d477bdd8a14151708 409 SUPERFAMILY SSF55874 212 380 1.7E-45 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS25365 47cd65b2ba4b3a2d477bdd8a14151708 409 Pfam PF00512 His Kinase A (phospho-acceptor) domain 157 221 5.1E-14 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 BWK49_RS25365 47cd65b2ba4b3a2d477bdd8a14151708 409 SMART SM00387 267 379 3.6E-38 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS19235 35477d82950ba7ee723d15f21f2c7dfc 114 Pfam PF05305 Protein of unknown function (DUF732) 6 99 6.6E-27 T 06-07-2017 IPR007969 Domain of unknown function DUF732 BWK49_RS26280 9b9e47c7ba0256def5dffd97eec6da2c 467 Gene3D G3DSA:3.40.50.720 11 261 8.0E-95 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS26280 9b9e47c7ba0256def5dffd97eec6da2c 467 Gene3D G3DSA:1.10.1040.10 262 462 2.0E-58 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 BWK49_RS26280 9b9e47c7ba0256def5dffd97eec6da2c 467 PRINTS PR00084 Mannitol dehydrogenase signature 198 211 3.1E-16 T 06-07-2017 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 BWK49_RS26280 9b9e47c7ba0256def5dffd97eec6da2c 467 PRINTS PR00084 Mannitol dehydrogenase signature 27 37 3.1E-16 T 06-07-2017 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 BWK49_RS26280 9b9e47c7ba0256def5dffd97eec6da2c 467 PRINTS PR00084 Mannitol dehydrogenase signature 159 172 3.1E-16 T 06-07-2017 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 BWK49_RS26280 9b9e47c7ba0256def5dffd97eec6da2c 467 PRINTS PR00084 Mannitol dehydrogenase signature 228 243 3.1E-16 T 06-07-2017 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 BWK49_RS26280 9b9e47c7ba0256def5dffd97eec6da2c 467 SUPERFAMILY SSF48179 263 463 6.12E-57 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 BWK49_RS26280 9b9e47c7ba0256def5dffd97eec6da2c 467 Pfam PF01232 Mannitol dehydrogenase Rossmann domain 26 168 2.9E-31 T 06-07-2017 IPR013131 Mannitol dehydrogenase, N-terminal GO:0016491|GO:0055114 BWK49_RS26280 9b9e47c7ba0256def5dffd97eec6da2c 467 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 197 433 7.1E-70 T 06-07-2017 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 BWK49_RS26280 9b9e47c7ba0256def5dffd97eec6da2c 467 SUPERFAMILY SSF51735 12 262 8.66E-88 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS25425 a340f6ab8036b42948fbf096c624fe9f 225 Hamap MF_00114 Deoxyribose-phosphate aldolase [deoC]. 8 225 31.805 T 06-07-2017 IPR028581 Deoxyribose-phosphate aldolase type I GO:0004139 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180 BWK49_RS25425 a340f6ab8036b42948fbf096c624fe9f 225 PIRSF PIRSF001357 4 224 1.0E-66 T 06-07-2017 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-71336 BWK49_RS25425 a340f6ab8036b42948fbf096c624fe9f 225 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 9 215 6.3E-61 T 06-07-2017 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-71336 BWK49_RS25425 a340f6ab8036b42948fbf096c624fe9f 225 Pfam PF01791 DeoC/LacD family aldolase 14 219 6.6E-15 T 06-07-2017 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-71336 BWK49_RS25425 a340f6ab8036b42948fbf096c624fe9f 225 Gene3D G3DSA:3.20.20.70 6 223 8.8E-82 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 BWK49_RS25425 a340f6ab8036b42948fbf096c624fe9f 225 SMART SM01133 9 223 2.7E-77 T 06-07-2017 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-71336 BWK49_RS25425 a340f6ab8036b42948fbf096c624fe9f 225 SUPERFAMILY SSF51569 6 222 1.36E-67 T 06-07-2017 BWK49_RS23350 49274cdee09af975efbecc606d4878f4 217 SMART SM01110 29 217 8.4E-78 T 06-07-2017 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 BWK49_RS23350 49274cdee09af975efbecc606d4878f4 217 SUPERFAMILY SSF53474 30 215 2.57E-35 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS23350 49274cdee09af975efbecc606d4878f4 217 Gene3D G3DSA:3.40.50.1820 25 215 8.0E-50 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS23350 49274cdee09af975efbecc606d4878f4 217 Pfam PF01083 Cutinase 31 214 5.5E-42 T 06-07-2017 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 BWK49_RS27465 372eff913a92a9a78962b1fdeb47a159 477 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 231 238 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 BWK49_RS27465 372eff913a92a9a78962b1fdeb47a159 477 SUPERFAMILY SSF53720 25 457 6.15E-123 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 BWK49_RS27465 372eff913a92a9a78962b1fdeb47a159 477 Pfam PF00171 Aldehyde dehydrogenase family 22 448 7.5E-92 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 BWK49_RS27465 372eff913a92a9a78962b1fdeb47a159 477 PIRSF PIRSF036492 4 477 4.9E-172 T 06-07-2017 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0004030|GO:0006081|GO:0055114 BWK49_RS27465 372eff913a92a9a78962b1fdeb47a159 477 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 259 270 - T 06-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 BWK49_RS27465 372eff913a92a9a78962b1fdeb47a159 477 Gene3D G3DSA:3.40.605.10 20 246 1.5E-61 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 BWK49_RS27465 372eff913a92a9a78962b1fdeb47a159 477 Gene3D G3DSA:3.40.309.10 247 428 7.0E-59 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 BWK49_RS28410 879d29a0775ab2f63781ae45d8e09b73 343 Gene3D G3DSA:3.40.50.1820 23 298 2.8E-62 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS28410 879d29a0775ab2f63781ae45d8e09b73 343 SUPERFAMILY SSF53474 20 296 1.03E-61 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS28410 879d29a0775ab2f63781ae45d8e09b73 343 PRINTS PR00111 Alpha/beta hydrolase fold signature 123 136 8.3E-13 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS28410 879d29a0775ab2f63781ae45d8e09b73 343 PRINTS PR00111 Alpha/beta hydrolase fold signature 109 122 8.3E-13 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS28410 879d29a0775ab2f63781ae45d8e09b73 343 PRINTS PR00111 Alpha/beta hydrolase fold signature 65 80 8.3E-13 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS28410 879d29a0775ab2f63781ae45d8e09b73 343 Pfam PF12697 Alpha/beta hydrolase family 42 289 1.0E-23 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS09325 ae35c2b5baf33fe0fc311d23aece4f11 381 Gene3D G3DSA:3.40.47.10 242 377 2.9E-21 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS09325 ae35c2b5baf33fe0fc311d23aece4f11 381 Gene3D G3DSA:3.40.47.10 133 174 2.9E-21 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS09325 ae35c2b5baf33fe0fc311d23aece4f11 381 Pfam PF00108 Thiolase, N-terminal domain 4 173 1.3E-12 T 06-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 BWK49_RS09325 ae35c2b5baf33fe0fc311d23aece4f11 381 PIRSF PIRSF000429 1 380 5.7E-43 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 BWK49_RS09325 ae35c2b5baf33fe0fc311d23aece4f11 381 Pfam PF02803 Thiolase, C-terminal domain 253 356 2.1E-10 T 06-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 BWK49_RS09325 ae35c2b5baf33fe0fc311d23aece4f11 381 SUPERFAMILY SSF53901 3 220 3.36E-36 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS09325 ae35c2b5baf33fe0fc311d23aece4f11 381 Gene3D G3DSA:3.40.47.10 185 215 3.8E-15 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS09325 ae35c2b5baf33fe0fc311d23aece4f11 381 Gene3D G3DSA:3.40.47.10 14 106 3.8E-15 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS09325 ae35c2b5baf33fe0fc311d23aece4f11 381 SUPERFAMILY SSF53901 254 359 2.3E-25 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS14470 ee5dc9af83713d93c14562cdee5d0cbe 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 55 1.8E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS14470 ee5dc9af83713d93c14562cdee5d0cbe 189 Gene3D G3DSA:1.10.357.10 7 180 2.6E-22 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS14470 ee5dc9af83713d93c14562cdee5d0cbe 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 1.7E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS14470 ee5dc9af83713d93c14562cdee5d0cbe 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 1.7E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS14470 ee5dc9af83713d93c14562cdee5d0cbe 189 SUPERFAMILY SSF46689 4 76 6.67E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS14470 ee5dc9af83713d93c14562cdee5d0cbe 189 SUPERFAMILY SSF48498 73 185 2.61E-15 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS23665 e5a4c4e149c163b5bc57125653fae4ae 385 SUPERFAMILY SSF51395 25 197 2.93E-84 T 06-07-2017 BWK49_RS23665 e5a4c4e149c163b5bc57125653fae4ae 385 SUPERFAMILY SSF51395 230 380 2.93E-84 T 06-07-2017 BWK49_RS23665 e5a4c4e149c163b5bc57125653fae4ae 385 PIRSF PIRSF000138 4 384 4.8E-111 T 06-07-2017 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 BWK49_RS23665 e5a4c4e149c163b5bc57125653fae4ae 385 Gene3D G3DSA:3.20.20.70 25 381 4.5E-116 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 BWK49_RS23665 e5a4c4e149c163b5bc57125653fae4ae 385 Pfam PF01070 FMN-dependent dehydrogenase 33 381 5.8E-106 T 06-07-2017 IPR000262 FMN-dependent dehydrogenase GO:0016491 BWK49_RS23665 e5a4c4e149c163b5bc57125653fae4ae 385 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 279 285 - T 06-07-2017 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 BWK49_RS22800 9a9f5b26e17d4c8e9a80fb957994c3b6 249 Gene3D G3DSA:3.40.50.720 4 248 3.5E-65 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS22800 9a9f5b26e17d4c8e9a80fb957994c3b6 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 2.0E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS22800 9a9f5b26e17d4c8e9a80fb957994c3b6 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 2.0E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS22800 9a9f5b26e17d4c8e9a80fb957994c3b6 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 2.0E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS22800 9a9f5b26e17d4c8e9a80fb957994c3b6 249 SUPERFAMILY SSF51735 5 248 3.88E-62 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS22800 9a9f5b26e17d4c8e9a80fb957994c3b6 249 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS22800 9a9f5b26e17d4c8e9a80fb957994c3b6 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 3.8E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS22800 9a9f5b26e17d4c8e9a80fb957994c3b6 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 3.8E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS22800 9a9f5b26e17d4c8e9a80fb957994c3b6 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 3.8E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS22800 9a9f5b26e17d4c8e9a80fb957994c3b6 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 3.8E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS22800 9a9f5b26e17d4c8e9a80fb957994c3b6 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 3.8E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS22800 9a9f5b26e17d4c8e9a80fb957994c3b6 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 3.8E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS22800 9a9f5b26e17d4c8e9a80fb957994c3b6 249 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 19 246 1.5E-44 T 06-07-2017 BWK49_RS25520 cf69eaf158490fca2f2c9aaa414a5d5d 167 Pfam PF05610 Protein of unknown function (DUF779) 22 122 4.1E-41 T 06-07-2017 IPR008497 Protein of unknown function DUF779 BWK49_RS12030 1377fe20bb53872501471e1b29cd6adb 391 ProSitePatterns PS00099 Thiolases active site. 373 386 - T 06-07-2017 IPR020610 Thiolase, active site GO:0008152|GO:0016747 BWK49_RS12030 1377fe20bb53872501471e1b29cd6adb 391 Gene3D G3DSA:3.40.47.10 152 190 1.5E-51 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS12030 1377fe20bb53872501471e1b29cd6adb 391 Gene3D G3DSA:3.40.47.10 276 391 1.5E-51 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS12030 1377fe20bb53872501471e1b29cd6adb 391 PIRSF PIRSF000429 1 391 4.3E-116 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 BWK49_RS12030 1377fe20bb53872501471e1b29cd6adb 391 Pfam PF02803 Thiolase, C-terminal domain 270 390 4.9E-37 T 06-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 BWK49_RS12030 1377fe20bb53872501471e1b29cd6adb 391 Pfam PF00108 Thiolase, N-terminal domain 5 261 1.2E-51 T 06-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 BWK49_RS12030 1377fe20bb53872501471e1b29cd6adb 391 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 390 4.0E-110 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 BWK49_RS12030 1377fe20bb53872501471e1b29cd6adb 391 SUPERFAMILY SSF53901 272 390 4.33E-37 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS12030 1377fe20bb53872501471e1b29cd6adb 391 SUPERFAMILY SSF53901 1 265 1.03E-57 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS12030 1377fe20bb53872501471e1b29cd6adb 391 Gene3D G3DSA:3.40.47.10 5 121 3.0E-46 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS12030 1377fe20bb53872501471e1b29cd6adb 391 Gene3D G3DSA:3.40.47.10 191 274 3.0E-46 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS15225 45742c4a60d33fbae9cb890607ba6f1e 607 Gene3D G3DSA:3.40.50.200 75 156 9.1E-64 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 BWK49_RS15225 45742c4a60d33fbae9cb890607ba6f1e 607 Gene3D G3DSA:3.40.50.200 283 544 9.1E-64 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 BWK49_RS15225 45742c4a60d33fbae9cb890607ba6f1e 607 Pfam PF00082 Subtilase family 285 535 9.6E-22 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 BWK49_RS15225 45742c4a60d33fbae9cb890607ba6f1e 607 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 105 115 - T 06-07-2017 IPR023827 Peptidase S8, subtilisin, Asp-active site BWK49_RS15225 45742c4a60d33fbae9cb890607ba6f1e 607 SUPERFAMILY SSF52743 83 153 6.62E-44 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 BWK49_RS15225 45742c4a60d33fbae9cb890607ba6f1e 607 SUPERFAMILY SSF52743 281 545 6.62E-44 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 BWK49_RS15225 45742c4a60d33fbae9cb890607ba6f1e 607 PRINTS PR00723 Subtilisin serine protease family (S8) signature 100 119 1.1E-9 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related BWK49_RS15225 45742c4a60d33fbae9cb890607ba6f1e 607 PRINTS PR00723 Subtilisin serine protease family (S8) signature 485 501 1.1E-9 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related BWK49_RS15225 45742c4a60d33fbae9cb890607ba6f1e 607 PRINTS PR00723 Subtilisin serine protease family (S8) signature 136 149 1.1E-9 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related BWK49_RS23780 11a0f73b2f3bc524be3ea06536afbcd4 192 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 53 85 - T 06-07-2017 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS23780 11a0f73b2f3bc524be3ea06536afbcd4 192 Pfam PF08281 Sigma-70, region 4 132 181 5.0E-10 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS23780 11a0f73b2f3bc524be3ea06536afbcd4 192 Gene3D G3DSA:1.10.1740.10 10 121 8.6E-19 T 06-07-2017 BWK49_RS23780 11a0f73b2f3bc524be3ea06536afbcd4 192 SUPERFAMILY SSF88946 4 117 3.73E-17 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS23780 11a0f73b2f3bc524be3ea06536afbcd4 192 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 23 185 3.8E-20 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS23780 11a0f73b2f3bc524be3ea06536afbcd4 192 Gene3D G3DSA:1.10.10.10 129 185 1.2E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS23780 11a0f73b2f3bc524be3ea06536afbcd4 192 SUPERFAMILY SSF88659 114 185 8.22E-14 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS23780 11a0f73b2f3bc524be3ea06536afbcd4 192 Pfam PF04542 Sigma-70 region 2 29 99 1.6E-12 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS17100 3fd60f759e93548b447af14cb665441d 723 SMART SM00487 36 451 2.0E-28 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain BWK49_RS17100 3fd60f759e93548b447af14cb665441d 723 Pfam PF00271 Helicase conserved C-terminal domain 459 571 1.2E-18 T 06-07-2017 IPR001650 Helicase, C-terminal BWK49_RS17100 3fd60f759e93548b447af14cb665441d 723 Gene3D G3DSA:3.40.50.300 445 608 5.2E-39 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS17100 3fd60f759e93548b447af14cb665441d 723 Hamap MF_00204 UvrABC system protein B [uvrB]. 30 713 43.119 T 06-07-2017 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 BWK49_RS17100 3fd60f759e93548b447af14cb665441d 723 SUPERFAMILY SSF52540 485 606 1.66E-34 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS17100 3fd60f759e93548b447af14cb665441d 723 SUPERFAMILY SSF52540 60 109 1.66E-34 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS17100 3fd60f759e93548b447af14cb665441d 723 SMART SM00490 486 572 3.4E-18 T 06-07-2017 IPR001650 Helicase, C-terminal BWK49_RS17100 3fd60f759e93548b447af14cb665441d 723 Pfam PF02151 UvrB/uvrC motif 680 713 1.7E-7 T 06-07-2017 IPR001943 UVR domain GO:0005515 BWK49_RS17100 3fd60f759e93548b447af14cb665441d 723 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 31 711 0.0 T 06-07-2017 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 BWK49_RS17100 3fd60f759e93548b447af14cb665441d 723 SUPERFAMILY SSF52540 32 441 8.15E-131 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS17100 3fd60f759e93548b447af14cb665441d 723 Gene3D G3DSA:3.40.50.300 304 364 1.4E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS17100 3fd60f759e93548b447af14cb665441d 723 Gene3D G3DSA:3.40.50.300 33 116 1.4E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS17100 3fd60f759e93548b447af14cb665441d 723 Gene3D G3DSA:3.40.50.300 414 435 1.4E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS17100 3fd60f759e93548b447af14cb665441d 723 Gene3D G3DSA:4.10.860.10 668 716 4.0E-15 T 06-07-2017 IPR001943 UVR domain GO:0005515 BWK49_RS17100 3fd60f759e93548b447af14cb665441d 723 Pfam PF12344 Ultra-violet resistance protein B 578 619 7.6E-23 T 06-07-2017 IPR024759 UvrB, YAD/RRR-motif-containing domain BWK49_RS17100 3fd60f759e93548b447af14cb665441d 723 Gene3D G3DSA:3.30.2060.10 186 255 1.0E-10 T 06-07-2017 BWK49_RS17100 3fd60f759e93548b447af14cb665441d 723 SUPERFAMILY SSF46600 668 715 2.35E-11 T 06-07-2017 IPR001943 UVR domain GO:0005515 BWK49_RS17100 3fd60f759e93548b447af14cb665441d 723 Pfam PF04851 Type III restriction enzyme, res subunit 43 165 7.7E-9 T 06-07-2017 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 BWK49_RS08680 5abb5320b21feae6369550b6c218d1cc 455 SUPERFAMILY SSF56176 4 214 2.1E-71 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 BWK49_RS08680 5abb5320b21feae6369550b6c218d1cc 455 Gene3D G3DSA:1.10.45.10 415 455 2.3E-15 T 06-07-2017 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 BWK49_RS08680 5abb5320b21feae6369550b6c218d1cc 455 SUPERFAMILY SSF55103 191 453 7.19E-54 T 06-07-2017 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 BWK49_RS08680 5abb5320b21feae6369550b6c218d1cc 455 Gene3D G3DSA:3.30.43.10 3 94 2.4E-26 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 BWK49_RS08680 5abb5320b21feae6369550b6c218d1cc 455 Gene3D G3DSA:3.30.465.10 97 214 9.7E-40 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 BWK49_RS08680 5abb5320b21feae6369550b6c218d1cc 455 Pfam PF01565 FAD binding domain 41 178 3.5E-42 T 06-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 BWK49_RS08680 5abb5320b21feae6369550b6c218d1cc 455 Pfam PF02913 FAD linked oxidases, C-terminal domain 218 452 4.9E-63 T 06-07-2017 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 BWK49_RS00305 f3fe7145a8ceab004a5efc98879f03b3 337 SUPERFAMILY SSF51735 1 310 4.35E-48 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS00305 f3fe7145a8ceab004a5efc98879f03b3 337 Gene3D G3DSA:3.40.50.720 1 258 4.9E-43 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS00305 f3fe7145a8ceab004a5efc98879f03b3 337 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 231 1.4E-20 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 BWK49_RS03980 15d659313c0414eb54ca4aeb080e8936 141 SUPERFAMILY SSF54593 1 138 2.42E-20 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS03980 15d659313c0414eb54ca4aeb080e8936 141 Gene3D G3DSA:3.10.180.10 6 134 5.3E-21 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS03980 15d659313c0414eb54ca4aeb080e8936 141 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 132 5.3E-7 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain BWK49_RS19750 917c77cf11116e4caa2699e6ccac8bb2 452 Pfam PF02720 Domain of unknown function (DUF222) 39 363 6.7E-89 T 06-07-2017 IPR003870 Domain of unknown function DUF222 BWK49_RS19750 917c77cf11116e4caa2699e6ccac8bb2 452 ProDom PD008243 RV1792C/MT1741/MB1728C RV1945/MT1995 MB1980 MB0098C RV3466/MT3572 VERY RV1128C/MT1160 RV1148C/MT1183 MB1159C RV0095C 27 97 2.0E-20 T 06-07-2017 BWK49_RS19750 917c77cf11116e4caa2699e6ccac8bb2 452 SMART SM00507 354 406 3.5E-8 T 06-07-2017 IPR003615 HNH nuclease BWK49_RS01585 4ac07c0beefb16dd2ef8afea2d781734 177 SUPERFAMILY SSF46785 21 165 8.71E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS01585 4ac07c0beefb16dd2ef8afea2d781734 177 SMART SM00347 47 148 1.2E-21 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 BWK49_RS01585 4ac07c0beefb16dd2ef8afea2d781734 177 Pfam PF01047 MarR family 54 113 1.3E-11 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 BWK49_RS01585 4ac07c0beefb16dd2ef8afea2d781734 177 PRINTS PR00598 Bacterial regulatory protein MarR family signature 72 88 1.4E-7 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 BWK49_RS01585 4ac07c0beefb16dd2ef8afea2d781734 177 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 104 1.4E-7 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 BWK49_RS01585 4ac07c0beefb16dd2ef8afea2d781734 177 PRINTS PR00598 Bacterial regulatory protein MarR family signature 108 124 1.4E-7 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 BWK49_RS01585 4ac07c0beefb16dd2ef8afea2d781734 177 Gene3D G3DSA:1.10.10.10 16 163 9.6E-34 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS27760 952e29414e3235919d5a9410121383fa 219 SUPERFAMILY SSF53335 42 193 6.98E-30 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS27760 952e29414e3235919d5a9410121383fa 219 Gene3D G3DSA:3.40.50.150 40 194 1.5E-38 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS27760 952e29414e3235919d5a9410121383fa 219 Pfam PF13578 Methyltransferase domain 76 178 4.2E-15 T 06-07-2017 BWK49_RS17360 3bb875347227a45828ff6ef935769763 241 SUPERFAMILY SSF46785 156 228 9.25E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS17360 3bb875347227a45828ff6ef935769763 241 Pfam PF00293 NUDIX domain 36 141 2.0E-9 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 BWK49_RS17360 3bb875347227a45828ff6ef935769763 241 SUPERFAMILY SSF55811 33 152 1.76E-25 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 BWK49_RS17360 3bb875347227a45828ff6ef935769763 241 Gene3D G3DSA:1.10.10.10 150 230 4.6E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS17360 3bb875347227a45828ff6ef935769763 241 Gene3D G3DSA:3.90.79.10 5 144 2.5E-28 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 BWK49_RS01240 e4890225785c3988efbb1d9c70743bb0 254 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 147 175 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS01240 e4890225785c3988efbb1d9c70743bb0 254 Gene3D G3DSA:3.40.50.720 10 226 1.1E-33 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS01240 e4890225785c3988efbb1d9c70743bb0 254 SUPERFAMILY SSF51735 9 251 2.28E-37 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS01240 e4890225785c3988efbb1d9c70743bb0 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 3.8E-15 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS01240 e4890225785c3988efbb1d9c70743bb0 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 3.8E-15 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS01240 e4890225785c3988efbb1d9c70743bb0 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 3.8E-15 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS01240 e4890225785c3988efbb1d9c70743bb0 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 3.8E-15 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS01240 e4890225785c3988efbb1d9c70743bb0 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 3.8E-15 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS01240 e4890225785c3988efbb1d9c70743bb0 254 Pfam PF00106 short chain dehydrogenase 11 203 2.6E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS11230 a7c5b092f80030c1ae3cc016ec1e0df8 108 SUPERFAMILY SSF54862 5 53 1.43E-19 T 06-07-2017 BWK49_RS11230 a7c5b092f80030c1ae3cc016ec1e0df8 108 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 31 42 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site BWK49_RS11230 a7c5b092f80030c1ae3cc016ec1e0df8 108 Gene3D G3DSA:3.30.70.20 6 58 8.9E-17 T 06-07-2017 BWK49_RS11230 a7c5b092f80030c1ae3cc016ec1e0df8 108 Pfam PF00037 4Fe-4S binding domain 25 47 1.2E-8 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain BWK49_RS11230 a7c5b092f80030c1ae3cc016ec1e0df8 108 PRINTS PR00354 7Fe ferredoxin signature 26 43 2.5E-13 T 06-07-2017 IPR000813 7Fe ferredoxin GO:0009055 BWK49_RS11230 a7c5b092f80030c1ae3cc016ec1e0df8 108 PRINTS PR00354 7Fe ferredoxin signature 10 20 2.5E-13 T 06-07-2017 IPR000813 7Fe ferredoxin GO:0009055 BWK49_RS02410 a4e29d54f18851cacb651c0e9ae54879 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 1.9E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS02410 a4e29d54f18851cacb651c0e9ae54879 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 1.9E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS02410 a4e29d54f18851cacb651c0e9ae54879 194 SUPERFAMILY SSF46689 4 86 6.67E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS02410 a4e29d54f18851cacb651c0e9ae54879 194 Gene3D G3DSA:1.10.357.10 9 190 2.7E-35 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS02410 a4e29d54f18851cacb651c0e9ae54879 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 63 2.3E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS27055 0e7b759b807f25ca1840dd768f8b2406 254 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 31 254 27.249 T 06-07-2017 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 BWK49_RS27055 0e7b759b807f25ca1840dd768f8b2406 254 Pfam PF02390 Putative methyltransferase 80 247 9.3E-56 T 06-07-2017 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 BWK49_RS27055 0e7b759b807f25ca1840dd768f8b2406 254 Gene3D G3DSA:3.40.50.150 80 193 2.9E-12 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS27055 0e7b759b807f25ca1840dd768f8b2406 254 SUPERFAMILY SSF53335 79 252 3.99E-27 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS27055 0e7b759b807f25ca1840dd768f8b2406 254 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 76 246 4.2E-38 T 06-07-2017 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 BWK49_RS00070 1d581ed1ca5ad754df85fa704ab3a470 404 PRINTS PR00359 B-class P450 signature 296 323 1.0E-34 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS00070 1d581ed1ca5ad754df85fa704ab3a470 404 PRINTS PR00359 B-class P450 signature 156 171 1.0E-34 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS00070 1d581ed1ca5ad754df85fa704ab3a470 404 PRINTS PR00359 B-class P450 signature 199 221 1.0E-34 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS00070 1d581ed1ca5ad754df85fa704ab3a470 404 PRINTS PR00359 B-class P450 signature 93 104 1.0E-34 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS00070 1d581ed1ca5ad754df85fa704ab3a470 404 PRINTS PR00359 B-class P450 signature 324 339 1.0E-34 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS00070 1d581ed1ca5ad754df85fa704ab3a470 404 PRINTS PR00359 B-class P450 signature 279 290 1.0E-34 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS00070 1d581ed1ca5ad754df85fa704ab3a470 404 PRINTS PR00359 B-class P450 signature 346 355 1.0E-34 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS00070 1d581ed1ca5ad754df85fa704ab3a470 404 PRINTS PR00359 B-class P450 signature 139 155 1.0E-34 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS00070 1d581ed1ca5ad754df85fa704ab3a470 404 PRINTS PR00359 B-class P450 signature 355 366 1.0E-34 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS00070 1d581ed1ca5ad754df85fa704ab3a470 404 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 348 357 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 BWK49_RS00070 1d581ed1ca5ad754df85fa704ab3a470 404 SUPERFAMILY SSF48264 9 403 1.05E-75 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS00070 1d581ed1ca5ad754df85fa704ab3a470 404 Pfam PF00067 Cytochrome P450 262 379 2.2E-21 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS00070 1d581ed1ca5ad754df85fa704ab3a470 404 Gene3D G3DSA:1.10.630.10 8 403 3.1E-88 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS16240 7ee5093bddf60624265d60920d3d565f 1135 SUPERFAMILY SSF52540 429 562 4.26E-14 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS16240 7ee5093bddf60624265d60920d3d565f 1135 SUPERFAMILY SSF52540 296 361 4.26E-14 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS16240 7ee5093bddf60624265d60920d3d565f 1135 Gene3D G3DSA:1.25.40.10 698 871 7.7E-8 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 BWK49_RS16240 7ee5093bddf60624265d60920d3d565f 1135 Gene3D G3DSA:1.25.40.10 922 1125 2.0E-12 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 BWK49_RS16240 7ee5093bddf60624265d60920d3d565f 1135 Gene3D G3DSA:3.40.50.300 406 488 1.8E-6 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS16240 7ee5093bddf60624265d60920d3d565f 1135 Gene3D G3DSA:3.40.50.300 292 347 1.8E-6 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS16240 7ee5093bddf60624265d60920d3d565f 1135 SMART SM00028 1043 1078 92.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 BWK49_RS16240 7ee5093bddf60624265d60920d3d565f 1135 SMART SM00028 835 868 80.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 BWK49_RS16240 7ee5093bddf60624265d60920d3d565f 1135 SMART SM00028 1003 1036 120.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 BWK49_RS16240 7ee5093bddf60624265d60920d3d565f 1135 SMART SM00028 923 956 82.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 BWK49_RS16240 7ee5093bddf60624265d60920d3d565f 1135 Pfam PF13191 AAA ATPase domain 297 480 7.3E-26 T 06-07-2017 BWK49_RS16240 7ee5093bddf60624265d60920d3d565f 1135 SUPERFAMILY SSF48452 921 958 1.33E-9 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 BWK49_RS16240 7ee5093bddf60624265d60920d3d565f 1135 SUPERFAMILY SSF48452 772 872 1.33E-9 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 BWK49_RS16240 7ee5093bddf60624265d60920d3d565f 1135 SUPERFAMILY SSF48452 896 1091 8.63E-13 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 BWK49_RS16240 7ee5093bddf60624265d60920d3d565f 1135 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 97 272 1.0E-22 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 BWK49_RS16240 7ee5093bddf60624265d60920d3d565f 1135 SUPERFAMILY SSF55073 96 278 5.81E-49 T 06-07-2017 IPR029787 Nucleotide cyclase BWK49_RS16240 7ee5093bddf60624265d60920d3d565f 1135 SMART SM00044 49 259 4.9E-14 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 BWK49_RS16240 7ee5093bddf60624265d60920d3d565f 1135 Gene3D G3DSA:3.30.70.1230 97 279 9.6E-35 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 BWK49_RS03900 8ac60601d2c0426ca6049369f57e1b1c 536 Gene3D G3DSA:1.20.1250.20 293 452 1.2E-20 T 06-07-2017 BWK49_RS03900 8ac60601d2c0426ca6049369f57e1b1c 536 Gene3D G3DSA:1.20.1250.20 44 219 5.7E-28 T 06-07-2017 BWK49_RS03900 8ac60601d2c0426ca6049369f57e1b1c 536 Gene3D G3DSA:1.20.1250.20 502 527 1.2E-20 T 06-07-2017 BWK49_RS03900 8ac60601d2c0426ca6049369f57e1b1c 536 Pfam PF07690 Major Facilitator Superfamily 46 442 2.8E-49 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 BWK49_RS03900 8ac60601d2c0426ca6049369f57e1b1c 536 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 42 524 3.6E-135 T 06-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 BWK49_RS03900 8ac60601d2c0426ca6049369f57e1b1c 536 SUPERFAMILY SSF103473 278 451 7.19E-67 T 06-07-2017 IPR020846 Major facilitator superfamily domain BWK49_RS03900 8ac60601d2c0426ca6049369f57e1b1c 536 SUPERFAMILY SSF103473 501 528 7.19E-67 T 06-07-2017 IPR020846 Major facilitator superfamily domain BWK49_RS03900 8ac60601d2c0426ca6049369f57e1b1c 536 SUPERFAMILY SSF103473 28 223 7.19E-67 T 06-07-2017 IPR020846 Major facilitator superfamily domain BWK49_RS17695 7c20049a4ec00a8b8558804fab75185f 434 Gene3D G3DSA:1.20.5.100 198 225 1.2E-18 T 06-07-2017 BWK49_RS17695 7c20049a4ec00a8b8558804fab75185f 434 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 414 4.5E-135 T 06-07-2017 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 BWK49_RS17695 7c20049a4ec00a8b8558804fab75185f 434 PIRSF PIRSF000124 1 433 9.4E-141 T 06-07-2017 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 BWK49_RS17695 7c20049a4ec00a8b8558804fab75185f 434 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 195 287 6.2E-38 T 06-07-2017 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 BWK49_RS17695 7c20049a4ec00a8b8558804fab75185f 434 Gene3D G3DSA:3.40.50.720 1 197 8.8E-75 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS17695 7c20049a4ec00a8b8558804fab75185f 434 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 177 5.1E-61 T 06-07-2017 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 BWK49_RS17695 7c20049a4ec00a8b8558804fab75185f 434 PIRSF PIRSF500134 1 434 7.7E-179 T 06-07-2017 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00500+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346 BWK49_RS17695 7c20049a4ec00a8b8558804fab75185f 434 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 316 418 1.3E-30 T 06-07-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 BWK49_RS17695 7c20049a4ec00a8b8558804fab75185f 434 SUPERFAMILY SSF48179 195 292 9.18E-34 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 BWK49_RS17695 7c20049a4ec00a8b8558804fab75185f 434 SUPERFAMILY SSF52413 306 429 2.22E-36 T 06-07-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 BWK49_RS17695 7c20049a4ec00a8b8558804fab75185f 434 Gene3D G3DSA:3.40.50.720 226 433 7.4E-71 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS17695 7c20049a4ec00a8b8558804fab75185f 434 SMART SM00984 316 418 2.7E-45 T 06-07-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 BWK49_RS17695 7c20049a4ec00a8b8558804fab75185f 434 SUPERFAMILY SSF51735 1 187 2.09E-51 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS09760 28227bd164b3194039b4569a97ab57d8 393 SUPERFAMILY SSF52777 167 392 7.12E-62 T 06-07-2017 BWK49_RS09760 28227bd164b3194039b4569a97ab57d8 393 Pfam PF00364 Biotin-requiring enzyme 12 84 4.2E-19 T 06-07-2017 IPR000089 Biotin/lipoyl attachment BWK49_RS09760 28227bd164b3194039b4569a97ab57d8 393 Gene3D G3DSA:3.30.559.10 167 390 1.2E-61 T 06-07-2017 IPR023213 Chloramphenicol acetyltransferase-like domain Reactome: R-HSA-389661 BWK49_RS09760 28227bd164b3194039b4569a97ab57d8 393 Gene3D G3DSA:4.10.320.10 118 162 3.8E-6 T 06-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 BWK49_RS09760 28227bd164b3194039b4569a97ab57d8 393 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 168 389 1.0E-63 T 06-07-2017 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 BWK49_RS09760 28227bd164b3194039b4569a97ab57d8 393 SUPERFAMILY SSF51230 11 99 1.18E-23 T 06-07-2017 IPR011053 Single hybrid motif BWK49_RS09760 28227bd164b3194039b4569a97ab57d8 393 Gene3D G3DSA:2.40.50.100 13 86 2.8E-23 T 06-07-2017 BWK49_RS22940 86480500d2f5a19651ea8dd32d0fa328 490 Gene3D G3DSA:3.40.50.720 250 409 4.6E-48 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS22940 86480500d2f5a19651ea8dd32d0fa328 490 Gene3D G3DSA:3.40.50.1480 17 249 3.8E-143 T 06-07-2017 BWK49_RS22940 86480500d2f5a19651ea8dd32d0fa328 490 Gene3D G3DSA:3.40.50.1480 411 490 3.8E-143 T 06-07-2017 BWK49_RS22940 86480500d2f5a19651ea8dd32d0fa328 490 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 89 103 - T 06-07-2017 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 BWK49_RS22940 86480500d2f5a19651ea8dd32d0fa328 490 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 17 489 5.2E-146 T 06-07-2017 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 BWK49_RS22940 86480500d2f5a19651ea8dd32d0fa328 490 SMART SM00997 248 410 2.6E-103 T 06-07-2017 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 BWK49_RS22940 86480500d2f5a19651ea8dd32d0fa328 490 SMART SM00996 17 489 0.0 T 06-07-2017 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 BWK49_RS22940 86480500d2f5a19651ea8dd32d0fa328 490 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 270 286 - T 06-07-2017 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 BWK49_RS22940 86480500d2f5a19651ea8dd32d0fa328 490 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 18 482 4.4E-199 T 06-07-2017 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 BWK49_RS22940 86480500d2f5a19651ea8dd32d0fa328 490 SUPERFAMILY SSF52283 200 247 9.07E-112 T 06-07-2017 BWK49_RS22940 86480500d2f5a19651ea8dd32d0fa328 490 SUPERFAMILY SSF52283 16 162 9.07E-112 T 06-07-2017 BWK49_RS22940 86480500d2f5a19651ea8dd32d0fa328 490 SUPERFAMILY SSF52283 411 490 9.07E-112 T 06-07-2017 BWK49_RS22940 86480500d2f5a19651ea8dd32d0fa328 490 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 13 482 47.617 T 06-07-2017 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 BWK49_RS22940 86480500d2f5a19651ea8dd32d0fa328 490 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 248 410 6.1E-80 T 06-07-2017 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 BWK49_RS22940 86480500d2f5a19651ea8dd32d0fa328 490 SUPERFAMILY SSF51735 248 410 3.95E-70 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS22940 86480500d2f5a19651ea8dd32d0fa328 490 PIRSF PIRSF001109 4 490 1.1E-199 T 06-07-2017 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 BWK49_RS14490 33a5b083d4715b14ba9a771a9d5d5ddd 321 Gene3D G3DSA:3.20.20.70 12 298 5.4E-59 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 BWK49_RS14490 33a5b083d4715b14ba9a771a9d5d5ddd 321 SUPERFAMILY SSF51412 12 308 5.34E-58 T 06-07-2017 BWK49_RS14490 33a5b083d4715b14ba9a771a9d5d5ddd 321 Pfam PF03060 Nitronate monooxygenase 14 300 4.5E-50 T 06-07-2017 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 BWK49_RS19835 116033b3184c2da6fd10ee13c1a445de 325 PIRSF PIRSF004491 2 325 1.2E-94 T 06-07-2017 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168 BWK49_RS19835 116033b3184c2da6fd10ee13c1a445de 325 Pfam PF06574 FAD synthetase 13 160 3.7E-51 T 06-07-2017 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168 BWK49_RS19835 116033b3184c2da6fd10ee13c1a445de 325 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 18 321 2.4E-67 T 06-07-2017 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168 BWK49_RS19835 116033b3184c2da6fd10ee13c1a445de 325 Gene3D G3DSA:2.40.30.30 185 323 2.7E-44 T 06-07-2017 IPR023465 Riboflavin kinase domain GO:0008531|GO:0009231 Reactome: R-HSA-196843 BWK49_RS19835 116033b3184c2da6fd10ee13c1a445de 325 SUPERFAMILY SSF52374 16 179 1.15E-29 T 06-07-2017 BWK49_RS19835 116033b3184c2da6fd10ee13c1a445de 325 Gene3D G3DSA:3.40.50.620 3 184 3.1E-60 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold BWK49_RS19835 116033b3184c2da6fd10ee13c1a445de 325 Pfam PF01687 Riboflavin kinase 188 321 4.5E-34 T 06-07-2017 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 BWK49_RS19835 116033b3184c2da6fd10ee13c1a445de 325 SMART SM00904 187 322 1.2E-51 T 06-07-2017 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 BWK49_RS19835 116033b3184c2da6fd10ee13c1a445de 325 SUPERFAMILY SSF82114 178 323 3.71E-40 T 06-07-2017 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 BWK49_RS27630 03d29560bd6394aaefd419f0554e261e 279 Gene3D G3DSA:3.40.50.1820 13 278 4.7E-62 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS27630 03d29560bd6394aaefd419f0554e261e 279 PRINTS PR00111 Alpha/beta hydrolase fold signature 52 67 1.0E-11 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS27630 03d29560bd6394aaefd419f0554e261e 279 PRINTS PR00111 Alpha/beta hydrolase fold signature 221 235 1.0E-11 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS27630 03d29560bd6394aaefd419f0554e261e 279 PRINTS PR00111 Alpha/beta hydrolase fold signature 96 109 1.0E-11 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS27630 03d29560bd6394aaefd419f0554e261e 279 Pfam PF00561 alpha/beta hydrolase fold 27 264 1.5E-25 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS27630 03d29560bd6394aaefd419f0554e261e 279 PRINTS PR00412 Epoxide hydrolase signature 52 67 1.2E-6 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS27630 03d29560bd6394aaefd419f0554e261e 279 PRINTS PR00412 Epoxide hydrolase signature 253 275 1.2E-6 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS27630 03d29560bd6394aaefd419f0554e261e 279 PRINTS PR00412 Epoxide hydrolase signature 32 50 1.2E-6 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS27630 03d29560bd6394aaefd419f0554e261e 279 SUPERFAMILY SSF53474 12 278 3.81E-61 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS11180 e82370271c16461fc1cb9545606bd20f 63 PRINTS PR00352 3Fe-4S ferredoxin signature 47 59 3.1E-5 T 06-07-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 BWK49_RS11180 e82370271c16461fc1cb9545606bd20f 63 PRINTS PR00352 3Fe-4S ferredoxin signature 16 26 3.1E-5 T 06-07-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 BWK49_RS11180 e82370271c16461fc1cb9545606bd20f 63 PRINTS PR00352 3Fe-4S ferredoxin signature 5 16 3.1E-5 T 06-07-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 BWK49_RS11180 e82370271c16461fc1cb9545606bd20f 63 Gene3D G3DSA:3.30.70.20 1 63 3.9E-18 T 06-07-2017 BWK49_RS11180 e82370271c16461fc1cb9545606bd20f 63 Pfam PF13459 4Fe-4S single cluster domain 3 59 1.7E-17 T 06-07-2017 BWK49_RS11180 e82370271c16461fc1cb9545606bd20f 63 SUPERFAMILY SSF54862 2 60 1.38E-12 T 06-07-2017 BWK49_RS15500 6ff73ba2dd413e2984fd6c8a6509805f 319 SUPERFAMILY SSF51735 13 265 8.75E-52 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS15500 6ff73ba2dd413e2984fd6c8a6509805f 319 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 17 34 4.3E-15 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15500 6ff73ba2dd413e2984fd6c8a6509805f 319 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 200 217 4.3E-15 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15500 6ff73ba2dd413e2984fd6c8a6509805f 319 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 93 104 4.3E-15 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15500 6ff73ba2dd413e2984fd6c8a6509805f 319 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 139 155 4.3E-15 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15500 6ff73ba2dd413e2984fd6c8a6509805f 319 Pfam PF00106 short chain dehydrogenase 17 218 3.6E-27 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15500 6ff73ba2dd413e2984fd6c8a6509805f 319 Gene3D G3DSA:3.40.50.720 7 265 4.0E-56 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS07010 22954df4336e6606df7df2d71437e9fe 527 SUPERFAMILY SSF52335 14 202 1.1E-63 T 06-07-2017 IPR011607 Methylglyoxal synthase-like domain BWK49_RS07010 22954df4336e6606df7df2d71437e9fe 527 SUPERFAMILY SSF53927 223 527 1.3E-114 T 06-07-2017 IPR016193 Cytidine deaminase-like GO:0003824 BWK49_RS07010 22954df4336e6606df7df2d71437e9fe 527 Pfam PF02142 MGS-like domain 26 139 6.7E-25 T 06-07-2017 IPR011607 Methylglyoxal synthase-like domain BWK49_RS07010 22954df4336e6606df7df2d71437e9fe 527 SMART SM00798 145 462 2.5E-183 T 06-07-2017 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 BWK49_RS07010 22954df4336e6606df7df2d71437e9fe 527 Gene3D G3DSA:3.40.50.1380 12 195 1.4E-76 T 06-07-2017 IPR011607 Methylglyoxal synthase-like domain BWK49_RS07010 22954df4336e6606df7df2d71437e9fe 527 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 15 527 1.1E-169 T 06-07-2017 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 BWK49_RS07010 22954df4336e6606df7df2d71437e9fe 527 PIRSF PIRSF000414 8 527 1.0E-190 T 06-07-2017 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 BWK49_RS07010 22954df4336e6606df7df2d71437e9fe 527 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 14 527 41.995 T 06-07-2017 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 BWK49_RS07010 22954df4336e6606df7df2d71437e9fe 527 Gene3D G3DSA:3.40.140.20 253 368 2.9E-44 T 06-07-2017 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 BWK49_RS07010 22954df4336e6606df7df2d71437e9fe 527 Pfam PF01808 AICARFT/IMPCHase bienzyme 145 461 1.8E-113 T 06-07-2017 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 BWK49_RS07010 22954df4336e6606df7df2d71437e9fe 527 SMART SM00851 26 140 4.5E-47 T 06-07-2017 IPR011607 Methylglyoxal synthase-like domain BWK49_RS07010 22954df4336e6606df7df2d71437e9fe 527 Gene3D G3DSA:3.40.140.20 375 517 1.4E-50 T 06-07-2017 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 BWK49_RS00075 093b07a9b70e3cb1855a10ccdd22bd13 144 Hamap MF_00927 Cell wall synthesis protein CwsA [cwsA]. 4 144 28.233 T 06-07-2017 IPR024245 Cell wall synthesis protein CwsA BWK49_RS00075 093b07a9b70e3cb1855a10ccdd22bd13 144 ProDom PD070500 MEMBRANE TRANSMEMBRANE MB0008C RV0008C/MT0010 1 101 8.0E-28 T 06-07-2017 IPR024245 Cell wall synthesis protein CwsA BWK49_RS00075 093b07a9b70e3cb1855a10ccdd22bd13 144 Pfam PF10814 Protein of unknown function (DUF2562) 9 144 2.6E-62 T 06-07-2017 IPR024245 Cell wall synthesis protein CwsA BWK49_RS15745 6b359455aad2f22a18371827a9c2badb 541 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 12 212 2.6E-13 T 06-07-2017 BWK49_RS15745 6b359455aad2f22a18371827a9c2badb 541 SUPERFAMILY SSF51905 9 235 5.18E-54 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS15745 6b359455aad2f22a18371827a9c2badb 541 Gene3D G3DSA:3.50.50.60 9 215 7.6E-63 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS15745 6b359455aad2f22a18371827a9c2badb 541 Gene3D G3DSA:3.50.50.60 269 534 2.9E-16 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS15745 6b359455aad2f22a18371827a9c2badb 541 SUPERFAMILY SSF51905 269 536 3.63E-27 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS15745 6b359455aad2f22a18371827a9c2badb 541 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 138 147 4.9E-6 T 06-07-2017 BWK49_RS15745 6b359455aad2f22a18371827a9c2badb 541 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 10 32 4.9E-6 T 06-07-2017 BWK49_RS15745 6b359455aad2f22a18371827a9c2badb 541 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 180 205 4.9E-6 T 06-07-2017 BWK49_RS11455 0eb8c51c22cb452374165a333ae3904b 436 SMART SM00116 209 258 1.2 T 06-07-2017 IPR000644 CBS domain BWK49_RS11455 0eb8c51c22cb452374165a333ae3904b 436 SMART SM00116 275 323 5.0 T 06-07-2017 IPR000644 CBS domain BWK49_RS11455 0eb8c51c22cb452374165a333ae3904b 436 Gene3D G3DSA:3.10.580.10 185 330 1.8E-21 T 06-07-2017 BWK49_RS11455 0eb8c51c22cb452374165a333ae3904b 436 SMART SM01091 339 422 5.1E-19 T 06-07-2017 IPR005170 Transporter-associated domain BWK49_RS11455 0eb8c51c22cb452374165a333ae3904b 436 SUPERFAMILY SSF56176 338 428 2.73E-13 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 BWK49_RS11455 0eb8c51c22cb452374165a333ae3904b 436 Gene3D G3DSA:3.30.465.10 331 414 4.5E-25 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 BWK49_RS11455 0eb8c51c22cb452374165a333ae3904b 436 Pfam PF00571 CBS domain 206 255 3.7E-4 T 06-07-2017 IPR000644 CBS domain BWK49_RS11455 0eb8c51c22cb452374165a333ae3904b 436 Pfam PF00571 CBS domain 269 323 4.5E-6 T 06-07-2017 IPR000644 CBS domain BWK49_RS11455 0eb8c51c22cb452374165a333ae3904b 436 Pfam PF01595 Domain of unknown function DUF21 9 185 1.2E-30 T 06-07-2017 IPR002550 Domain of unknown function DUF21 BWK49_RS11455 0eb8c51c22cb452374165a333ae3904b 436 Pfam PF03471 Transporter associated domain 341 408 1.3E-11 T 06-07-2017 IPR005170 Transporter-associated domain BWK49_RS11455 0eb8c51c22cb452374165a333ae3904b 436 SUPERFAMILY SSF54631 195 335 4.3E-34 T 06-07-2017 BWK49_RS26490 7b694aa1d7a831b7564e54bb9537fc8b 101 Gene3D G3DSA:4.10.830.10 41 101 2.1E-27 T 06-07-2017 BWK49_RS26490 7b694aa1d7a831b7564e54bb9537fc8b 101 Hamap MF_00537 30S ribosomal protein S14 [rpsN]. 1 101 26.187 T 06-07-2017 IPR023036 Ribosomal protein S14, bacterial/plastid BWK49_RS26490 7b694aa1d7a831b7564e54bb9537fc8b 101 SUPERFAMILY SSF57716 2 101 5.7E-33 T 06-07-2017 BWK49_RS26490 7b694aa1d7a831b7564e54bb9537fc8b 101 Pfam PF00253 Ribosomal protein S14p/S29e 48 100 2.7E-23 T 06-07-2017 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS28245 815f6c45d3d74d69b6014a5cff219987 1404 Gene3D G3DSA:3.40.50.300 524 710 6.1E-19 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS28245 815f6c45d3d74d69b6014a5cff219987 1404 TIGRFAM TIGR03924 T7SS_EccC_a: type VII secretion protein EccCa 24 746 4.0E-218 T 06-07-2017 IPR023836 EccCa-like, Actinobacteria BWK49_RS28245 815f6c45d3d74d69b6014a5cff219987 1404 Gene3D G3DSA:3.40.50.300 1181 1332 1.1E-9 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS28245 815f6c45d3d74d69b6014a5cff219987 1404 SUPERFAMILY SSF52540 498 710 4.11E-16 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS28245 815f6c45d3d74d69b6014a5cff219987 1404 SUPERFAMILY SSF52540 823 1075 3.16E-6 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS28245 815f6c45d3d74d69b6014a5cff219987 1404 Pfam PF01580 FtsK/SpoIIIE family 524 708 3.9E-16 T 06-07-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 BWK49_RS28245 815f6c45d3d74d69b6014a5cff219987 1404 Pfam PF01580 FtsK/SpoIIIE family 841 1102 3.1E-74 T 06-07-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 BWK49_RS28245 815f6c45d3d74d69b6014a5cff219987 1404 SUPERFAMILY SSF52540 1167 1334 1.89E-6 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS28245 815f6c45d3d74d69b6014a5cff219987 1404 TIGRFAM TIGR03925 T7SS_EccC_b: type VII secretion protein EccCb 807 1393 1.3E-163 T 06-07-2017 IPR023837 EccCb-like, Actinobacteria BWK49_RS14225 64e4beb7673b0df4cb70435caa68c677 307 Pfam PF04072 Leucine carboxyl methyltransferase 24 206 2.9E-67 T 06-07-2017 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 BWK49_RS14225 64e4beb7673b0df4cb70435caa68c677 307 Gene3D G3DSA:3.40.50.150 18 244 2.2E-19 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS14225 64e4beb7673b0df4cb70435caa68c677 307 SUPERFAMILY SSF53335 20 288 2.99E-79 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS14225 64e4beb7673b0df4cb70435caa68c677 307 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 22 283 3.6E-86 T 06-07-2017 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 BWK49_RS00025 d86705f5158d9094cd5f7b765f41f13f 677 Pfam PF01751 Toprim domain 456 566 2.5E-16 T 06-07-2017 IPR006171 Toprim domain BWK49_RS00025 d86705f5158d9094cd5f7b765f41f13f 677 PRINTS PR00418 DNA topoisomerase II family signature 41 56 1.6E-69 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 BWK49_RS00025 d86705f5158d9094cd5f7b765f41f13f 677 PRINTS PR00418 DNA topoisomerase II family signature 561 573 1.6E-69 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 BWK49_RS00025 d86705f5158d9094cd5f7b765f41f13f 677 PRINTS PR00418 DNA topoisomerase II family signature 541 558 1.6E-69 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 BWK49_RS00025 d86705f5158d9094cd5f7b765f41f13f 677 PRINTS PR00418 DNA topoisomerase II family signature 120 134 1.6E-69 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 BWK49_RS00025 d86705f5158d9094cd5f7b765f41f13f 677 PRINTS PR00418 DNA topoisomerase II family signature 76 89 1.6E-69 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 BWK49_RS00025 d86705f5158d9094cd5f7b765f41f13f 677 PRINTS PR00418 DNA topoisomerase II family signature 609 625 1.6E-69 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 BWK49_RS00025 d86705f5158d9094cd5f7b765f41f13f 677 PRINTS PR00418 DNA topoisomerase II family signature 457 471 1.6E-69 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 BWK49_RS00025 d86705f5158d9094cd5f7b765f41f13f 677 PRINTS PR00418 DNA topoisomerase II family signature 305 318 1.6E-69 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 BWK49_RS00025 d86705f5158d9094cd5f7b765f41f13f 677 PRINTS PR00418 DNA topoisomerase II family signature 523 539 1.6E-69 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 BWK49_RS00025 d86705f5158d9094cd5f7b765f41f13f 677 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 9 677 95.841 T 06-07-2017 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 BWK49_RS00025 d86705f5158d9094cd5f7b765f41f13f 677 SUPERFAMILY SSF54211 258 428 3.6E-60 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold BWK49_RS00025 d86705f5158d9094cd5f7b765f41f13f 677 PRINTS PR01159 DNA gyrase subunit B signature 186 201 2.7E-74 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 BWK49_RS00025 d86705f5158d9094cd5f7b765f41f13f 677 PRINTS PR01159 DNA gyrase subunit B signature 201 214 2.7E-74 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 BWK49_RS00025 d86705f5158d9094cd5f7b765f41f13f 677 PRINTS PR01159 DNA gyrase subunit B signature 349 365 2.7E-74 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 BWK49_RS00025 d86705f5158d9094cd5f7b765f41f13f 677 PRINTS PR01159 DNA gyrase subunit B signature 397 411 2.7E-74 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 BWK49_RS00025 d86705f5158d9094cd5f7b765f41f13f 677 PRINTS PR01159 DNA gyrase subunit B signature 257 279 2.7E-74 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 BWK49_RS00025 d86705f5158d9094cd5f7b765f41f13f 677 PRINTS PR01159 DNA gyrase subunit B signature 646 662 2.7E-74 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 BWK49_RS00025 d86705f5158d9094cd5f7b765f41f13f 677 PRINTS PR01159 DNA gyrase subunit B signature 507 516 2.7E-74 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 BWK49_RS00025 d86705f5158d9094cd5f7b765f41f13f 677 PRINTS PR01159 DNA gyrase subunit B signature 630 642 2.7E-74 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 BWK49_RS00025 d86705f5158d9094cd5f7b765f41f13f 677 PRINTS PR01159 DNA gyrase subunit B signature 411 431 2.7E-74 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 BWK49_RS00025 d86705f5158d9094cd5f7b765f41f13f 677 PRINTS PR01159 DNA gyrase subunit B signature 12 22 2.7E-74 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 BWK49_RS00025 d86705f5158d9094cd5f7b765f41f13f 677 SUPERFAMILY SSF55874 12 218 1.44E-65 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS00025 d86705f5158d9094cd5f7b765f41f13f 677 Gene3D G3DSA:3.40.50.670 441 658 1.5E-87 T 06-07-2017 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 BWK49_RS00025 d86705f5158d9094cd5f7b765f41f13f 677 ProSitePatterns PS00177 DNA topoisomerase II signature. 459 467 - T 06-07-2017 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 BWK49_RS00025 d86705f5158d9094cd5f7b765f41f13f 677 SUPERFAMILY SSF56719 431 672 3.14E-81 T 06-07-2017 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 BWK49_RS00025 d86705f5158d9094cd5f7b765f41f13f 677 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 12 677 1.2E-297 T 06-07-2017 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 BWK49_RS00025 d86705f5158d9094cd5f7b765f41f13f 677 SMART SM00387 37 181 2.2E-24 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS00025 d86705f5158d9094cd5f7b765f41f13f 677 Pfam PF00204 DNA gyrase B 258 427 2.7E-63 T 06-07-2017 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 BWK49_RS00025 d86705f5158d9094cd5f7b765f41f13f 677 Gene3D G3DSA:3.30.230.10 257 428 1.0E-75 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup BWK49_RS00025 d86705f5158d9094cd5f7b765f41f13f 677 Gene3D G3DSA:3.30.565.10 12 219 1.1E-85 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS00025 d86705f5158d9094cd5f7b765f41f13f 677 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 608 665 1.3E-25 T 06-07-2017 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 BWK49_RS00025 d86705f5158d9094cd5f7b765f41f13f 677 SMART SM00433 41 670 0.0 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 BWK49_RS00025 d86705f5158d9094cd5f7b765f41f13f 677 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 39 180 2.0E-23 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS11390 ed830290963e6b7c906b1363fa54fc2d 428 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 87 283 1.8E-12 T 06-07-2017 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase BWK49_RS11390 ed830290963e6b7c906b1363fa54fc2d 428 Gene3D G3DSA:3.50.50.60 207 295 9.1E-5 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS11390 ed830290963e6b7c906b1363fa54fc2d 428 Gene3D G3DSA:3.40.50.720 109 206 6.6E-6 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS11390 ed830290963e6b7c906b1363fa54fc2d 428 Gene3D G3DSA:3.40.50.720 5 46 6.6E-6 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS11390 ed830290963e6b7c906b1363fa54fc2d 428 SUPERFAMILY SSF51905 190 363 2.52E-5 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS11390 ed830290963e6b7c906b1363fa54fc2d 428 SUPERFAMILY SSF51905 4 235 9.93E-11 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS26325 41864f1e7da13bd30d9feb652df4f1e3 355 SMART SM00829 29 347 8.2E-5 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 BWK49_RS26325 41864f1e7da13bd30d9feb652df4f1e3 355 Pfam PF16884 N-terminal domain of oxidoreductase 23 124 2.6E-30 T 06-07-2017 BWK49_RS26325 41864f1e7da13bd30d9feb652df4f1e3 355 Gene3D G3DSA:3.90.180.10 22 158 5.6E-41 T 06-07-2017 IPR011032 GroES-like BWK49_RS26325 41864f1e7da13bd30d9feb652df4f1e3 355 SUPERFAMILY SSF51735 141 315 4.29E-45 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS26325 41864f1e7da13bd30d9feb652df4f1e3 355 Gene3D G3DSA:3.40.50.720 159 316 1.4E-58 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS26325 41864f1e7da13bd30d9feb652df4f1e3 355 SUPERFAMILY SSF50129 22 160 5.05E-30 T 06-07-2017 IPR011032 GroES-like BWK49_RS26325 41864f1e7da13bd30d9feb652df4f1e3 355 Pfam PF00107 Zinc-binding dehydrogenase 176 295 6.0E-22 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 BWK49_RS09470 8cbae9819852a9fd5397a7c01e9ad370 383 Gene3D G3DSA:1.10.540.10 7 120 1.2E-12 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS09470 8cbae9819852a9fd5397a7c01e9ad370 383 SUPERFAMILY SSF56645 2 224 1.96E-36 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS09470 8cbae9819852a9fd5397a7c01e9ad370 383 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 243 368 4.3E-25 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS09470 8cbae9819852a9fd5397a7c01e9ad370 383 SUPERFAMILY SSF47203 240 374 2.54E-35 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS09470 8cbae9819852a9fd5397a7c01e9ad370 383 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 126 199 1.1E-8 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 BWK49_RS09470 8cbae9819852a9fd5397a7c01e9ad370 383 Gene3D G3DSA:1.20.140.10 218 373 2.1E-35 T 06-07-2017 BWK49_RS09470 8cbae9819852a9fd5397a7c01e9ad370 383 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 120 1.9E-13 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS09470 8cbae9819852a9fd5397a7c01e9ad370 383 Gene3D G3DSA:2.40.110.10 124 217 2.2E-15 T 06-07-2017 BWK49_RS22790 e092ae130f060ee87efd5dfa5304ae2f 149 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 120 8.1E-16 T 06-07-2017 BWK49_RS22790 e092ae130f060ee87efd5dfa5304ae2f 149 Gene3D G3DSA:3.10.180.10 8 132 2.3E-16 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS22790 e092ae130f060ee87efd5dfa5304ae2f 149 SUPERFAMILY SSF54593 8 141 8.73E-18 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS12375 fea7bd4699bb3c4e426d41d253741426 570 SUPERFAMILY SSF53067 163 343 2.92E-23 T 06-07-2017 BWK49_RS12375 fea7bd4699bb3c4e426d41d253741426 570 Gene3D G3DSA:3.30.420.40 164 326 1.5E-10 T 06-07-2017 BWK49_RS12375 fea7bd4699bb3c4e426d41d253741426 570 Pfam PF00012 Hsp70 protein 163 344 3.9E-9 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 BWK49_RS24620 973b820aa10fb34c75fb9f947ed89656 55 Pfam PF00471 Ribosomal protein L33 10 55 2.8E-23 T 06-07-2017 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS24620 973b820aa10fb34c75fb9f947ed89656 55 ProSitePatterns PS00582 Ribosomal protein L33 signature. 23 42 - T 06-07-2017 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS24620 973b820aa10fb34c75fb9f947ed89656 55 SUPERFAMILY SSF57829 5 55 7.94E-20 T 06-07-2017 IPR011332 Zinc-binding ribosomal protein GO:0006412 BWK49_RS24620 973b820aa10fb34c75fb9f947ed89656 55 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 6 55 2.4E-21 T 06-07-2017 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS24620 973b820aa10fb34c75fb9f947ed89656 55 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 7 55 19.619 T 06-07-2017 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS01870 e59f97dcb4f274b0b8b3bc3e8b5e24e4 263 SUPERFAMILY SSF51735 9 253 1.07E-73 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS01870 e59f97dcb4f274b0b8b3bc3e8b5e24e4 263 Gene3D G3DSA:3.40.50.720 8 253 3.5E-76 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS01870 e59f97dcb4f274b0b8b3bc3e8b5e24e4 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 5.0E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS01870 e59f97dcb4f274b0b8b3bc3e8b5e24e4 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 5.0E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS01870 e59f97dcb4f274b0b8b3bc3e8b5e24e4 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 5.0E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS01870 e59f97dcb4f274b0b8b3bc3e8b5e24e4 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 5.0E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS01870 e59f97dcb4f274b0b8b3bc3e8b5e24e4 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 5.0E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS01870 e59f97dcb4f274b0b8b3bc3e8b5e24e4 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 5.0E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS01870 e59f97dcb4f274b0b8b3bc3e8b5e24e4 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 1.4E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS01870 e59f97dcb4f274b0b8b3bc3e8b5e24e4 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 1.4E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS01870 e59f97dcb4f274b0b8b3bc3e8b5e24e4 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 1.4E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS01870 e59f97dcb4f274b0b8b3bc3e8b5e24e4 263 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 252 7.6E-60 T 06-07-2017 BWK49_RS01870 e59f97dcb4f274b0b8b3bc3e8b5e24e4 263 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS25800 77e90ff20fb06b05115a5a18a1a94d29 461 Gene3D G3DSA:3.40.710.10 3 329 1.2E-76 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like BWK49_RS25800 77e90ff20fb06b05115a5a18a1a94d29 461 Pfam PF00144 Beta-lactamase 6 329 3.3E-69 T 06-07-2017 IPR001466 Beta-lactamase-related BWK49_RS25800 77e90ff20fb06b05115a5a18a1a94d29 461 SUPERFAMILY SSF56601 3 336 1.18E-78 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like BWK49_RS17475 eb9048325e3fbb34446b1b1517beaae1 442 Gene3D G3DSA:3.90.1150.10 299 434 4.7E-12 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 BWK49_RS17475 eb9048325e3fbb34446b1b1517beaae1 442 Gene3D G3DSA:3.40.640.10 125 298 1.2E-25 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 BWK49_RS17475 eb9048325e3fbb34446b1b1517beaae1 442 Pfam PF00155 Aminotransferase class I and II 149 430 9.2E-19 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 BWK49_RS17475 eb9048325e3fbb34446b1b1517beaae1 442 SMART SM00345 15 74 1.6E-17 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 BWK49_RS17475 eb9048325e3fbb34446b1b1517beaae1 442 SUPERFAMILY SSF53383 71 435 5.25E-59 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase BWK49_RS17475 eb9048325e3fbb34446b1b1517beaae1 442 Gene3D G3DSA:1.10.10.10 13 82 4.6E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS17475 eb9048325e3fbb34446b1b1517beaae1 442 SUPERFAMILY SSF46785 12 78 5.79E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS17475 eb9048325e3fbb34446b1b1517beaae1 442 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 74 2.7E-16 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 BWK49_RS09750 90b3f08149b9b34c90ebc03b8913ee84 355 TIGRFAM TIGR03181 PDH_E1_alph_x: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 7 346 2.3E-132 T 06-07-2017 IPR017596 Pyruvate dehydrogenase E1 component subunit alpha/BCKADH E1-alpha KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 BWK49_RS09750 90b3f08149b9b34c90ebc03b8913ee84 355 Gene3D G3DSA:3.40.50.970 4 346 4.7E-125 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS09750 90b3f08149b9b34c90ebc03b8913ee84 355 SUPERFAMILY SSF52518 26 349 1.97E-100 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS09750 90b3f08149b9b34c90ebc03b8913ee84 355 Pfam PF00676 Dehydrogenase E1 component 37 320 1.7E-84 T 06-07-2017 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 BWK49_RS01460 eb6ff2c4b100849ef3a93b241a89a0b0 285 Pfam PF02405 Permease MlaE 68 271 4.0E-43 T 06-07-2017 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 BWK49_RS28125 69e4b3aea15f1e8f32cea5b4c377c84a 449 Gene3D G3DSA:3.20.20.140 8 392 1.6E-66 T 06-07-2017 BWK49_RS28125 69e4b3aea15f1e8f32cea5b4c377c84a 449 Pfam PF04909 Amidohydrolase 53 375 6.2E-30 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 BWK49_RS28125 69e4b3aea15f1e8f32cea5b4c377c84a 449 SUPERFAMILY SSF51556 8 36 1.42E-72 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS28125 69e4b3aea15f1e8f32cea5b4c377c84a 449 SUPERFAMILY SSF51556 67 384 1.42E-72 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS12695 ebb0b572b0052e64e381096bab6f7321 152 Pfam PF12728 Helix-turn-helix domain 103 147 1.6E-9 T 06-07-2017 BWK49_RS12695 ebb0b572b0052e64e381096bab6f7321 152 SUPERFAMILY SSF46955 103 148 1.56E-5 T 06-07-2017 IPR009061 Putative DNA-binding domain BWK49_RS12695 ebb0b572b0052e64e381096bab6f7321 152 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 103 148 4.5E-9 T 06-07-2017 IPR010093 SinI-like, DNA-binding domain GO:0003677 BWK49_RS27870 bab0b0a1596bb789a6670702aea3bec2 523 ProSitePatterns PS00455 Putative AMP-binding domain signature. 184 195 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS27870 bab0b0a1596bb789a6670702aea3bec2 523 Gene3D G3DSA:3.40.50.980 191 353 9.3E-29 T 06-07-2017 BWK49_RS27870 bab0b0a1596bb789a6670702aea3bec2 523 Gene3D G3DSA:3.40.50.980 43 190 1.1E-29 T 06-07-2017 BWK49_RS27870 bab0b0a1596bb789a6670702aea3bec2 523 Pfam PF00501 AMP-binding enzyme 49 431 4.7E-68 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS27870 bab0b0a1596bb789a6670702aea3bec2 523 Gene3D G3DSA:2.30.38.10 354 424 3.0E-14 T 06-07-2017 BWK49_RS27870 bab0b0a1596bb789a6670702aea3bec2 523 SUPERFAMILY SSF56801 41 521 7.46E-120 T 06-07-2017 BWK49_RS27870 bab0b0a1596bb789a6670702aea3bec2 523 Pfam PF13193 AMP-binding enzyme C-terminal domain 441 515 2.2E-18 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS27870 bab0b0a1596bb789a6670702aea3bec2 523 Gene3D G3DSA:3.30.300.30 426 521 9.1E-33 T 06-07-2017 BWK49_RS13385 3f4b945548f49d47243b8510c774d88b 609 SUPERFAMILY SSF52540 497 553 5.6E-49 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS13385 3f4b945548f49d47243b8510c774d88b 609 SUPERFAMILY SSF52540 247 456 5.6E-49 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS13385 3f4b945548f49d47243b8510c774d88b 609 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 289 439 1.6E-47 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 BWK49_RS13385 3f4b945548f49d47243b8510c774d88b 609 Pfam PF16450 Proteasomal ATPase OB/ID domain 99 246 6.1E-54 T 06-07-2017 IPR032501 Proteasomal ATPase, OB/ID domain BWK49_RS13385 3f4b945548f49d47243b8510c774d88b 609 Hamap MF_02112 Proteasome-associated ATPase [mpa]. 57 588 50.438 T 06-07-2017 IPR022482 Proteasome ATPase GO:0000502|GO:0010498|GO:0016887|GO:0019941 BWK49_RS13385 3f4b945548f49d47243b8510c774d88b 609 TIGRFAM TIGR03689 pup_AAA: proteasome ATPase 55 587 6.5E-262 T 06-07-2017 IPR022482 Proteasome ATPase GO:0000502|GO:0010498|GO:0016887|GO:0019941 BWK49_RS13385 3f4b945548f49d47243b8510c774d88b 609 ProSitePatterns PS00674 AAA-protein family signature. 409 427 - T 06-07-2017 IPR003960 ATPase, AAA-type, conserved site GO:0005524 BWK49_RS13385 3f4b945548f49d47243b8510c774d88b 609 SMART SM00382 285 441 6.7E-22 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS13385 3f4b945548f49d47243b8510c774d88b 609 Gene3D G3DSA:3.40.50.300 238 456 1.3E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS04120 7b20bb36bb827cad096866328caf232e 262 Pfam PF00486 Transcriptional regulatory protein, C terminal 144 217 5.9E-28 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 BWK49_RS04120 7b20bb36bb827cad096866328caf232e 262 SMART SM00862 144 218 1.8E-27 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 BWK49_RS04120 7b20bb36bb827cad096866328caf232e 262 SUPERFAMILY SSF46894 122 217 9.92E-29 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 BWK49_RS04120 7b20bb36bb827cad096866328caf232e 262 Gene3D G3DSA:1.10.10.10 122 219 2.9E-34 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS21075 5b14bdc593e3fa742620e94889bfb92e 280 SUPERFAMILY SSF55729 20 244 2.49E-37 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase BWK49_RS21075 5b14bdc593e3fa742620e94889bfb92e 280 Pfam PF13444 Acetyltransferase (GNAT) domain 39 144 1.0E-26 T 06-07-2017 BWK49_RS21075 5b14bdc593e3fa742620e94889bfb92e 280 Gene3D G3DSA:3.40.630.30 27 196 9.5E-26 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase BWK49_RS12725 0e403404321f6200c8b26347e8a8a13f 677 Gene3D G3DSA:3.40.50.300 373 543 3.1E-6 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS12725 0e403404321f6200c8b26347e8a8a13f 677 Pfam PF13481 AAA domain 369 516 2.6E-9 T 06-07-2017 BWK49_RS12725 0e403404321f6200c8b26347e8a8a13f 677 SUPERFAMILY SSF52540 372 573 1.64E-6 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS05150 4ee6c1774f6dee56d9799f5d160d7ae7 146 SUPERFAMILY SSF54637 12 138 2.15E-26 T 06-07-2017 IPR029069 HotDog domain BWK49_RS05150 4ee6c1774f6dee56d9799f5d160d7ae7 146 Pfam PF03061 Thioesterase superfamily 54 131 6.1E-11 T 06-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 BWK49_RS05150 4ee6c1774f6dee56d9799f5d160d7ae7 146 Gene3D G3DSA:3.10.129.10 6 142 2.4E-30 T 06-07-2017 IPR029069 HotDog domain BWK49_RS05150 4ee6c1774f6dee56d9799f5d160d7ae7 146 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 25 137 2.3E-19 T 06-07-2017 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-75105 BWK49_RS01610 6cc402e3ed09688f0f208949516bbce3 67 Pfam PF09339 IclR helix-turn-helix domain 1 40 2.2E-12 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 BWK49_RS01610 6cc402e3ed09688f0f208949516bbce3 67 SUPERFAMILY SSF46785 1 59 8.89E-8 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS01610 6cc402e3ed09688f0f208949516bbce3 67 Gene3D G3DSA:1.10.10.10 1 48 8.6E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS01040 284f0b91d50cd51b0574807947e0a0b3 228 Gene3D G3DSA:3.40.50.1240 4 202 1.3E-38 T 06-07-2017 IPR029033 Histidine phosphatase superfamily BWK49_RS01040 284f0b91d50cd51b0574807947e0a0b3 228 SMART SM00855 4 162 1.1E-18 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 BWK49_RS01040 284f0b91d50cd51b0574807947e0a0b3 228 SUPERFAMILY SSF53254 4 203 2.94E-42 T 06-07-2017 IPR029033 Histidine phosphatase superfamily BWK49_RS01040 284f0b91d50cd51b0574807947e0a0b3 228 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 5 201 1.8E-38 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 BWK49_RS15980 4572cfc63c756b5abc6a4a6f2f9da1b7 263 SUPERFAMILY SSF54001 83 233 7.57E-29 T 06-07-2017 BWK49_RS15980 4572cfc63c756b5abc6a4a6f2f9da1b7 263 Pfam PF01841 Transglutaminase-like superfamily 110 205 3.1E-19 T 06-07-2017 IPR002931 Transglutaminase-like BWK49_RS15980 4572cfc63c756b5abc6a4a6f2f9da1b7 263 Gene3D G3DSA:3.90.260.10 151 207 7.2E-7 T 06-07-2017 IPR002931 Transglutaminase-like BWK49_RS15980 4572cfc63c756b5abc6a4a6f2f9da1b7 263 SMART SM00460 147 207 2.4E-14 T 06-07-2017 IPR002931 Transglutaminase-like BWK49_RS24575 09bd80390cb8f275c5f4e3b4ad309773 405 Gene3D G3DSA:1.10.1740.10 7 75 1.0E-9 T 06-07-2017 BWK49_RS24575 09bd80390cb8f275c5f4e3b4ad309773 405 SUPERFAMILY SSF88659 99 160 3.36E-9 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS24575 09bd80390cb8f275c5f4e3b4ad309773 405 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 20 160 7.1E-13 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS24575 09bd80390cb8f275c5f4e3b4ad309773 405 Pfam PF04542 Sigma-70 region 2 13 73 1.3E-10 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS24575 09bd80390cb8f275c5f4e3b4ad309773 405 SUPERFAMILY SSF88946 8 83 6.67E-12 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS24575 09bd80390cb8f275c5f4e3b4ad309773 405 Gene3D G3DSA:1.10.10.10 100 160 9.3E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS25110 f16decc08ca848c703b775d0f8523e1d 264 Gene3D G3DSA:3.40.50.1580 7 251 2.5E-75 T 06-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 BWK49_RS25110 f16decc08ca848c703b775d0f8523e1d 264 TIGRFAM TIGR01694 MTAP: methylthioadenosine phosphorylase 7 240 1.4E-90 T 06-07-2017 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112 BWK49_RS25110 f16decc08ca848c703b775d0f8523e1d 264 SUPERFAMILY SSF53167 7 252 1.14E-72 T 06-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 BWK49_RS25110 f16decc08ca848c703b775d0f8523e1d 264 Hamap MF_01963 S-methyl-5'-thioadenosine phosphorylase [mtnP]. 6 259 38.836 T 06-07-2017 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112 BWK49_RS25110 f16decc08ca848c703b775d0f8523e1d 264 Pfam PF01048 Phosphorylase superfamily 9 226 7.9E-37 T 06-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 BWK49_RS05410 21fec938b02c5ea4ec4bb06ef2e01489 192 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 18 114 1.7E-11 T 06-07-2017 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 BWK49_RS05410 21fec938b02c5ea4ec4bb06ef2e01489 192 Gene3D G3DSA:1.10.150.130 18 115 2.3E-17 T 06-07-2017 IPR023109 Integrase/recombinase, N-terminal BWK49_RS05410 21fec938b02c5ea4ec4bb06ef2e01489 192 SUPERFAMILY SSF56349 18 192 5.3E-10 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 BWK49_RS21665 baae3ee0e92af2f8da6ee0968a2aa8c5 487 Hamap MF_00692 UPF0061 protein YdiU [ydiU]. 7 473 45.017 T 06-07-2017 IPR003846 Uncharacterised protein family UPF0061 BWK49_RS21665 baae3ee0e92af2f8da6ee0968a2aa8c5 487 Pfam PF02696 Uncharacterized ACR, YdiU/UPF0061 family 14 456 4.1E-114 T 06-07-2017 IPR003846 Uncharacterised protein family UPF0061 BWK49_RS27785 1634b0b66b819873a7abb14db40ca6fb 316 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 158 186 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS27785 1634b0b66b819873a7abb14db40ca6fb 316 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 14 210 0.0025 T 06-07-2017 BWK49_RS27785 1634b0b66b819873a7abb14db40ca6fb 316 Gene3D G3DSA:3.40.50.720 8 248 1.7E-61 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS27785 1634b0b66b819873a7abb14db40ca6fb 316 Pfam PF00106 short chain dehydrogenase 15 205 5.8E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27785 1634b0b66b819873a7abb14db40ca6fb 316 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 15 32 2.6E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27785 1634b0b66b819873a7abb14db40ca6fb 316 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 192 209 2.6E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27785 1634b0b66b819873a7abb14db40ca6fb 316 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 190 2.6E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27785 1634b0b66b819873a7abb14db40ca6fb 316 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 161 2.6E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27785 1634b0b66b819873a7abb14db40ca6fb 316 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 98 109 2.6E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27785 1634b0b66b819873a7abb14db40ca6fb 316 SUPERFAMILY SSF51735 9 250 1.62E-62 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS27785 1634b0b66b819873a7abb14db40ca6fb 316 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 159 2.5E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27785 1634b0b66b819873a7abb14db40ca6fb 316 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 171 190 2.5E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27785 1634b0b66b819873a7abb14db40ca6fb 316 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 98 109 2.5E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS20775 fd1202e6a8036257e5bcdd3f3741b2fa 158 Gene3D G3DSA:1.10.530.10 57 130 1.7E-5 T 06-07-2017 BWK49_RS20775 fd1202e6a8036257e5bcdd3f3741b2fa 158 Pfam PF01464 Transglycosylase SLT domain 47 137 5.8E-6 T 06-07-2017 IPR008258 Transglycosylase SLT domain 1 BWK49_RS20775 fd1202e6a8036257e5bcdd3f3741b2fa 158 SUPERFAMILY SSF53955 45 137 1.84E-8 T 06-07-2017 IPR023346 Lysozyme-like domain BWK49_RS14255 9b15f7fc74a605140eace56aab30cd55 257 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 256 4.0E-52 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 BWK49_RS14255 9b15f7fc74a605140eace56aab30cd55 257 SUPERFAMILY SSF52096 2 257 3.1E-76 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS14255 9b15f7fc74a605140eace56aab30cd55 257 Gene3D G3DSA:3.90.226.10 2 255 8.6E-78 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS19290 766b396079f21c51e6b4229027c401db 231 SUPERFAMILY SSF54909 5 230 6.43E-78 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel BWK49_RS19290 766b396079f21c51e6b4229027c401db 231 Gene3D G3DSA:3.30.70.1030 15 132 2.5E-22 T 06-07-2017 BWK49_RS19290 766b396079f21c51e6b4229027c401db 231 Pfam PF06778 Chlorite dismutase 32 221 1.8E-74 T 06-07-2017 IPR010644 Putative heme-dependent peroxidase/Chlorite dismutase BWK49_RS19290 766b396079f21c51e6b4229027c401db 231 Gene3D G3DSA:3.30.70.1100 133 230 4.0E-43 T 06-07-2017 BWK49_RS02305 34ec5a532773877c07b9079909614ce4 477 PIRSF PIRSF019251 3 475 1.9E-172 T 06-07-2017 IPR026281 HTH-type transcriptional regulator RamB GO:0006355 BWK49_RS02305 34ec5a532773877c07b9079909614ce4 477 Gene3D G3DSA:1.10.260.40 7 78 4.3E-18 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 BWK49_RS02305 34ec5a532773877c07b9079909614ce4 477 SMART SM00530 12 67 7.6E-14 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 BWK49_RS02305 34ec5a532773877c07b9079909614ce4 477 SUPERFAMILY SSF47413 7 70 1.13E-13 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 BWK49_RS02305 34ec5a532773877c07b9079909614ce4 477 Pfam PF09856 Predicted transcriptional regulator (DUF2083) 315 471 1.6E-65 T 06-07-2017 IPR018653 Domain of unknown function DUF2083,transcriptional regulator BWK49_RS02305 34ec5a532773877c07b9079909614ce4 477 Pfam PF06114 Domain of unknown function (DUF955) 189 314 9.5E-18 T 06-07-2017 IPR010359 HTH domain, IrrE-type BWK49_RS02305 34ec5a532773877c07b9079909614ce4 477 Pfam PF01381 Helix-turn-helix 13 67 2.3E-12 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 BWK49_RS25650 184784c55c4b7a84ee43b65653f5267e 401 Gene3D G3DSA:2.170.190.11 44 130 1.2E-34 T 06-07-2017 BWK49_RS25650 184784c55c4b7a84ee43b65653f5267e 401 Gene3D G3DSA:3.40.980.10 161 333 5.7E-55 T 06-07-2017 IPR001453 MoaB/Mog domain BWK49_RS25650 184784c55c4b7a84ee43b65653f5267e 401 Pfam PF00994 Probable molybdopterin binding domain 180 317 1.2E-26 T 06-07-2017 IPR001453 MoaB/Mog domain BWK49_RS25650 184784c55c4b7a84ee43b65653f5267e 401 Pfam PF03454 MoeA C-terminal region (domain IV) 332 400 2.1E-14 T 06-07-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 BWK49_RS25650 184784c55c4b7a84ee43b65653f5267e 401 Pfam PF03453 MoeA N-terminal region (domain I and II) 3 166 3.1E-35 T 06-07-2017 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 BWK49_RS25650 184784c55c4b7a84ee43b65653f5267e 401 SMART SM00852 179 318 1.4E-37 T 06-07-2017 IPR001453 MoaB/Mog domain BWK49_RS25650 184784c55c4b7a84ee43b65653f5267e 401 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 177 314 2.7E-31 T 06-07-2017 IPR001453 MoaB/Mog domain BWK49_RS25650 184784c55c4b7a84ee43b65653f5267e 401 SUPERFAMILY SSF63867 327 400 1.57E-14 T 06-07-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 BWK49_RS25650 184784c55c4b7a84ee43b65653f5267e 401 SUPERFAMILY SSF53218 177 324 3.93E-38 T 06-07-2017 IPR001453 MoaB/Mog domain BWK49_RS25650 184784c55c4b7a84ee43b65653f5267e 401 Gene3D G3DSA:2.40.340.10 334 397 2.8E-13 T 06-07-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 BWK49_RS25650 184784c55c4b7a84ee43b65653f5267e 401 Gene3D G3DSA:3.90.105.10 131 160 1.9E-17 T 06-07-2017 BWK49_RS25650 184784c55c4b7a84ee43b65653f5267e 401 SUPERFAMILY SSF63882 1 175 1.96E-53 T 06-07-2017 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 BWK49_RS16705 d9190ff14b367d4e020c4ded6824c1eb 254 Pfam PF00005 ABC transporter 33 170 6.5E-31 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 BWK49_RS16705 d9190ff14b367d4e020c4ded6824c1eb 254 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 BWK49_RS16705 d9190ff14b367d4e020c4ded6824c1eb 254 SMART SM00382 42 226 7.1E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS16705 d9190ff14b367d4e020c4ded6824c1eb 254 SUPERFAMILY SSF52540 16 233 1.11E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS16705 d9190ff14b367d4e020c4ded6824c1eb 254 Gene3D G3DSA:3.40.50.300 12 232 6.4E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS27855 6e8e2732d8d36560a30ff346005324d7 255 SUPERFAMILY SSF51735 12 239 1.53E-35 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS27855 6e8e2732d8d36560a30ff346005324d7 255 Gene3D G3DSA:3.40.50.720 12 240 2.1E-36 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS27855 6e8e2732d8d36560a30ff346005324d7 255 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 15 195 0.0028 T 06-07-2017 BWK49_RS27855 6e8e2732d8d36560a30ff346005324d7 255 Pfam PF00106 short chain dehydrogenase 16 195 1.6E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27855 6e8e2732d8d36560a30ff346005324d7 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 16 33 1.7E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27855 6e8e2732d8d36560a30ff346005324d7 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 1.7E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27855 6e8e2732d8d36560a30ff346005324d7 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 1.7E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS23745 a361d9008a85e36c16c94f2b449cd19c 191 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 69 2.8E-18 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS23745 a361d9008a85e36c16c94f2b449cd19c 191 SUPERFAMILY SSF46689 14 83 1.08E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS23745 a361d9008a85e36c16c94f2b449cd19c 191 ProSitePatterns PS01081 TetR-type HTH domain signature. 35 66 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site BWK49_RS23745 a361d9008a85e36c16c94f2b449cd19c 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 2.1E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS23745 a361d9008a85e36c16c94f2b449cd19c 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 2.1E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS23745 a361d9008a85e36c16c94f2b449cd19c 191 Gene3D G3DSA:1.10.357.10 5 177 5.9E-27 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS26475 ec6703ddbe4cc3f7df6b62b167043294 399 Gene3D G3DSA:3.40.50.300 35 191 1.2E-13 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS26475 ec6703ddbe4cc3f7df6b62b167043294 399 Gene3D G3DSA:3.30.1220.10 235 299 3.0E-4 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal BWK49_RS26475 ec6703ddbe4cc3f7df6b62b167043294 399 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 51 175 1.2E-10 T 06-07-2017 IPR003495 CobW/HypB/UreG, nucleotide-binding domain BWK49_RS26475 ec6703ddbe4cc3f7df6b62b167043294 399 SUPERFAMILY SSF90002 238 298 3.79E-7 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal BWK49_RS26475 ec6703ddbe4cc3f7df6b62b167043294 399 SUPERFAMILY SSF90002 325 350 3.79E-7 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal BWK49_RS26475 ec6703ddbe4cc3f7df6b62b167043294 399 SMART SM00833 235 351 7.4E-36 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal BWK49_RS26475 ec6703ddbe4cc3f7df6b62b167043294 399 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 236 350 7.7E-15 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal BWK49_RS19385 3d93ef75f1dae8fd049667c38c1e29a2 233 Gene3D G3DSA:3.40.50.1820 168 210 4.3E-12 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS19385 3d93ef75f1dae8fd049667c38c1e29a2 233 Gene3D G3DSA:3.40.50.1820 8 100 4.3E-12 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS19385 3d93ef75f1dae8fd049667c38c1e29a2 233 SUPERFAMILY SSF53474 7 209 1.69E-16 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS03990 cd48a124f4f713173a290f30b9000502 348 Pfam PF00107 Zinc-binding dehydrogenase 177 275 3.2E-15 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 BWK49_RS03990 cd48a124f4f713173a290f30b9000502 348 SUPERFAMILY SSF51735 137 287 8.6E-30 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS03990 cd48a124f4f713173a290f30b9000502 348 SUPERFAMILY SSF50129 25 165 7.08E-30 T 06-07-2017 IPR011032 GroES-like BWK49_RS03990 cd48a124f4f713173a290f30b9000502 348 Gene3D G3DSA:3.40.50.720 171 271 3.8E-18 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS03990 cd48a124f4f713173a290f30b9000502 348 Gene3D G3DSA:3.90.180.10 25 170 3.3E-29 T 06-07-2017 IPR011032 GroES-like BWK49_RS03990 cd48a124f4f713173a290f30b9000502 348 SMART SM00829 34 345 3.1E-11 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 BWK49_RS01955 8743b78ed802452783c827e8cf85dd16 242 PRINTS PR00111 Alpha/beta hydrolase fold signature 25 40 9.5E-8 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS01955 8743b78ed802452783c827e8cf85dd16 242 PRINTS PR00111 Alpha/beta hydrolase fold signature 84 97 9.5E-8 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS01955 8743b78ed802452783c827e8cf85dd16 242 PRINTS PR00111 Alpha/beta hydrolase fold signature 70 83 9.5E-8 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS01955 8743b78ed802452783c827e8cf85dd16 242 PRINTS PR00111 Alpha/beta hydrolase fold signature 183 197 9.5E-8 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS01955 8743b78ed802452783c827e8cf85dd16 242 Pfam PF00561 alpha/beta hydrolase fold 16 111 2.4E-11 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS01955 8743b78ed802452783c827e8cf85dd16 242 SUPERFAMILY SSF53474 14 234 9.2E-40 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS01955 8743b78ed802452783c827e8cf85dd16 242 Gene3D G3DSA:3.40.50.1820 12 234 6.6E-41 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS10065 318e9f2b517f16051336cf2eaf476eac 210 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 10 201 4.6E-57 T 06-07-2017 IPR005248 Probable nicotinate-nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|Reactome: R-HSA-196807 BWK49_RS10065 318e9f2b517f16051336cf2eaf476eac 210 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 6 202 29.459 T 06-07-2017 IPR005248 Probable nicotinate-nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|Reactome: R-HSA-196807 BWK49_RS10065 318e9f2b517f16051336cf2eaf476eac 210 Pfam PF01467 Cytidylyltransferase-like 10 176 1.1E-32 T 06-07-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 BWK49_RS10065 318e9f2b517f16051336cf2eaf476eac 210 SUPERFAMILY SSF52374 7 201 5.94E-50 T 06-07-2017 BWK49_RS10065 318e9f2b517f16051336cf2eaf476eac 210 Gene3D G3DSA:3.40.50.620 6 203 1.4E-66 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold BWK49_RS10065 318e9f2b517f16051336cf2eaf476eac 210 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 9 71 3.5E-12 T 06-07-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 BWK49_RS11530 498c4572789774c3376d545f94d98edb 650 Gene3D G3DSA:1.20.50.20 391 446 1.5E-16 T 06-07-2017 BWK49_RS11530 498c4572789774c3376d545f94d98edb 650 SMART SM00766 500 629 9.2E-39 T 06-07-2017 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 BWK49_RS11530 498c4572789774c3376d545f94d98edb 650 SMART SM00400 53 107 5.0E-35 T 06-07-2017 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 BWK49_RS11530 498c4572789774c3376d545f94d98edb 650 Pfam PF13662 Toprim domain 279 349 5.2E-13 T 06-07-2017 IPR006171 Toprim domain BWK49_RS11530 498c4572789774c3376d545f94d98edb 650 SMART SM00493 278 356 2.0E-13 T 06-07-2017 IPR006171 Toprim domain BWK49_RS11530 498c4572789774c3376d545f94d98edb 650 SUPERFAMILY SSF56731 133 448 2.41E-93 T 06-07-2017 BWK49_RS11530 498c4572789774c3376d545f94d98edb 650 Gene3D G3DSA:3.90.980.10 133 259 1.4E-38 T 06-07-2017 IPR013264 DNA primase, catalytic core, N-terminal BWK49_RS11530 498c4572789774c3376d545f94d98edb 650 Gene3D G3DSA:3.90.580.10 19 116 1.5E-35 T 06-07-2017 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 BWK49_RS11530 498c4572789774c3376d545f94d98edb 650 Gene3D G3DSA:3.40.1360.10 260 389 1.1E-36 T 06-07-2017 BWK49_RS11530 498c4572789774c3376d545f94d98edb 650 Pfam PF08275 DNA primase catalytic core, N-terminal domain 143 270 9.1E-36 T 06-07-2017 IPR013264 DNA primase, catalytic core, N-terminal BWK49_RS11530 498c4572789774c3376d545f94d98edb 650 TIGRFAM TIGR01391 dnaG: DNA primase 21 439 1.8E-111 T 06-07-2017 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 BWK49_RS11530 498c4572789774c3376d545f94d98edb 650 SUPERFAMILY SSF57783 20 115 1.17E-32 T 06-07-2017 BWK49_RS11530 498c4572789774c3376d545f94d98edb 650 Pfam PF08278 DNA primase DnaG DnaB-binding 501 628 7.5E-31 T 06-07-2017 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 BWK49_RS11530 498c4572789774c3376d545f94d98edb 650 Hamap MF_00974 DNA primase [dnaG]. 20 634 25.919 T 06-07-2017 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 BWK49_RS11530 498c4572789774c3376d545f94d98edb 650 Pfam PF10410 DnaB-helicase binding domain of primase 392 446 1.3E-19 T 06-07-2017 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 BWK49_RS11530 498c4572789774c3376d545f94d98edb 650 Gene3D G3DSA:1.10.860.10 494 618 2.4E-4 T 06-07-2017 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal BWK49_RS11530 498c4572789774c3376d545f94d98edb 650 PIRSF PIRSF002811 18 640 2.7E-143 T 06-07-2017 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 BWK49_RS11530 498c4572789774c3376d545f94d98edb 650 Pfam PF01807 CHC2 zinc finger 22 116 1.3E-34 T 06-07-2017 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 BWK49_RS17270 2b51163f5a6236698f14a3877783eae2 419 SUPERFAMILY SSF53686 24 410 2.23E-148 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme BWK49_RS17270 2b51163f5a6236698f14a3877783eae2 419 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 28 409 1.8E-185 T 06-07-2017 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 BWK49_RS17270 2b51163f5a6236698f14a3877783eae2 419 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 101 115 - T 06-07-2017 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 BWK49_RS17270 2b51163f5a6236698f14a3877783eae2 419 Gene3D G3DSA:3.40.50.1100 198 412 3.8E-98 T 06-07-2017 BWK49_RS17270 2b51163f5a6236698f14a3877783eae2 419 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 74 398 3.1E-56 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme BWK49_RS17270 2b51163f5a6236698f14a3877783eae2 419 PIRSF PIRSF001413 17 413 1.2E-158 T 06-07-2017 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 BWK49_RS17270 2b51163f5a6236698f14a3877783eae2 419 Gene3D G3DSA:3.40.50.1100 119 197 5.9E-23 T 06-07-2017 BWK49_RS17270 2b51163f5a6236698f14a3877783eae2 419 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 23 411 51.786 T 06-07-2017 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 BWK49_RS20975 a850c25e4bc23512c1181b8a2f4931cb 343 Gene3D G3DSA:3.40.50.450 1 213 6.4E-75 T 06-07-2017 BWK49_RS20975 a850c25e4bc23512c1181b8a2f4931cb 343 PIRSF PIRSF000532 1 341 2.3E-113 T 06-07-2017 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 BWK49_RS20975 a850c25e4bc23512c1181b8a2f4931cb 343 Hamap MF_01976 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase [pfp]. 1 343 43.729 T 06-07-2017 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 BWK49_RS20975 a850c25e4bc23512c1181b8a2f4931cb 343 TIGRFAM TIGR02483 PFK_mixed: phosphofructokinase 2 324 1.4E-139 T 06-07-2017 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 BWK49_RS20975 a850c25e4bc23512c1181b8a2f4931cb 343 Pfam PF00365 Phosphofructokinase 2 298 2.7E-102 T 06-07-2017 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 BWK49_RS20975 a850c25e4bc23512c1181b8a2f4931cb 343 ProSitePatterns PS00433 Phosphofructokinase signature. 267 285 - T 06-07-2017 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 BWK49_RS20975 a850c25e4bc23512c1181b8a2f4931cb 343 SUPERFAMILY SSF53784 1 333 7.59E-121 T 06-07-2017 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 BWK49_RS20975 a850c25e4bc23512c1181b8a2f4931cb 343 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 5 24 1.4E-76 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 BWK49_RS20975 a850c25e4bc23512c1181b8a2f4931cb 343 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 177 194 1.4E-76 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 BWK49_RS20975 a850c25e4bc23512c1181b8a2f4931cb 343 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 263 285 1.4E-76 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 BWK49_RS20975 a850c25e4bc23512c1181b8a2f4931cb 343 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 94 110 1.4E-76 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 BWK49_RS20975 a850c25e4bc23512c1181b8a2f4931cb 343 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 139 157 1.4E-76 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 BWK49_RS20975 a850c25e4bc23512c1181b8a2f4931cb 343 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 31 44 1.4E-76 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 BWK49_RS20975 a850c25e4bc23512c1181b8a2f4931cb 343 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 159 175 1.4E-76 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 BWK49_RS20975 a850c25e4bc23512c1181b8a2f4931cb 343 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 213 225 1.4E-76 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 BWK49_RS20975 a850c25e4bc23512c1181b8a2f4931cb 343 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 121 138 1.4E-76 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 BWK49_RS23100 dc37a402685373943e6efa75bc95025e 374 Gene3D G3DSA:3.40.190.10 206 369 2.4E-15 T 06-07-2017 BWK49_RS23100 dc37a402685373943e6efa75bc95025e 374 PIRSF PIRSF002756 3 374 7.8E-76 T 06-07-2017 IPR005673 ABC transporter, phosphate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 BWK49_RS23100 dc37a402685373943e6efa75bc95025e 374 SUPERFAMILY SSF53850 51 372 1.59E-71 T 06-07-2017 BWK49_RS23100 dc37a402685373943e6efa75bc95025e 374 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 52 371 1.9E-115 T 06-07-2017 IPR005673 ABC transporter, phosphate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 BWK49_RS23100 dc37a402685373943e6efa75bc95025e 374 Pfam PF12849 PBP superfamily domain 45 341 4.5E-41 T 06-07-2017 IPR024370 PBP domain BWK49_RS23100 dc37a402685373943e6efa75bc95025e 374 Gene3D G3DSA:3.40.190.10 50 194 8.1E-54 T 06-07-2017 BWK49_RS14245 abddf2047f47a279a63cf529999d7445 1305 Gene3D G3DSA:3.40.50.300 68 224 4.1E-45 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS14245 abddf2047f47a279a63cf529999d7445 1305 TIGRFAM TIGR01967 DEAH_box_HrpA: RNA helicase HrpA 10 1299 0.0 T 06-07-2017 IPR010222 RNA helicase HrpA GO:0004004 BWK49_RS14245 abddf2047f47a279a63cf529999d7445 1305 Pfam PF00270 DEAD/DEAH box helicase 75 224 2.3E-5 T 06-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 BWK49_RS14245 abddf2047f47a279a63cf529999d7445 1305 Pfam PF04408 Helicase associated domain (HA2) 475 561 4.3E-19 T 06-07-2017 IPR007502 Helicase-associated domain GO:0004386 BWK49_RS14245 abddf2047f47a279a63cf529999d7445 1305 Pfam PF00271 Helicase conserved C-terminal domain 289 412 1.2E-9 T 06-07-2017 IPR001650 Helicase, C-terminal BWK49_RS14245 abddf2047f47a279a63cf529999d7445 1305 SMART SM00847 473 563 2.5E-35 T 06-07-2017 IPR007502 Helicase-associated domain GO:0004386 BWK49_RS14245 abddf2047f47a279a63cf529999d7445 1305 SMART SM00382 83 393 5.9E-6 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS14245 abddf2047f47a279a63cf529999d7445 1305 Pfam PF07717 Oligonucleotide/oligosaccharide-binding (OB)-fold 623 704 1.5E-14 T 06-07-2017 IPR011709 Domain of unknown function DUF1605 BWK49_RS14245 abddf2047f47a279a63cf529999d7445 1305 SMART SM00490 311 413 2.2E-13 T 06-07-2017 IPR001650 Helicase, C-terminal BWK49_RS14245 abddf2047f47a279a63cf529999d7445 1305 Pfam PF11898 Domain of unknown function (DUF3418) 718 1299 2.5E-208 T 06-07-2017 IPR024590 RNA helicase HrpA, C-terminal BWK49_RS14245 abddf2047f47a279a63cf529999d7445 1305 Gene3D G3DSA:3.40.50.300 267 430 4.7E-14 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS14245 abddf2047f47a279a63cf529999d7445 1305 SUPERFAMILY SSF52540 70 578 1.75E-106 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS14245 abddf2047f47a279a63cf529999d7445 1305 SMART SM00487 66 250 7.4E-29 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain BWK49_RS19075 2059f1f007834573b862c85d80db5527 256 Pfam PF01925 Sulfite exporter TauE/SafE 5 247 2.2E-41 T 06-07-2017 IPR002781 Transmembrane protein TauE-like GO:0016021 BWK49_RS06245 1570ae173298c886b3b74d6ac5fc35cb 214 Gene3D G3DSA:1.10.357.10 9 210 3.4E-37 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS06245 1570ae173298c886b3b74d6ac5fc35cb 214 SUPERFAMILY SSF46689 13 95 6.48E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS06245 1570ae173298c886b3b74d6ac5fc35cb 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 39 4.9E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS06245 1570ae173298c886b3b74d6ac5fc35cb 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 47 70 4.9E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS06245 1570ae173298c886b3b74d6ac5fc35cb 214 Pfam PF14246 AefR-like transcriptional repressor, C-terminal region 158 208 1.9E-5 T 06-07-2017 BWK49_RS06245 1570ae173298c886b3b74d6ac5fc35cb 214 Pfam PF00440 Bacterial regulatory proteins, tetR family 28 71 1.8E-13 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS06245 1570ae173298c886b3b74d6ac5fc35cb 214 SUPERFAMILY SSF48498 90 213 1.14E-8 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS20765 fe10b341613263a0cb39c367843a16e2 739 SUPERFAMILY SSF52540 418 637 1.22E-36 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS20765 fe10b341613263a0cb39c367843a16e2 739 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 24 707 9.0E-222 T 06-07-2017 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 BWK49_RS20765 fe10b341613263a0cb39c367843a16e2 739 SMART SM00490 545 630 4.0E-20 T 06-07-2017 IPR001650 Helicase, C-terminal BWK49_RS20765 fe10b341613263a0cb39c367843a16e2 739 SMART SM00487 284 488 3.2E-29 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain BWK49_RS20765 fe10b341613263a0cb39c367843a16e2 739 Gene3D G3DSA:3.40.50.300 276 484 1.1E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS20765 fe10b341613263a0cb39c367843a16e2 739 Gene3D G3DSA:2.40.50.140 57 141 9.8E-12 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS20765 fe10b341613263a0cb39c367843a16e2 739 Pfam PF17191 RecG wedge domain 11 121 1.5E-5 T 06-07-2017 IPR033454 RecG, wedge domain BWK49_RS20765 fe10b341613263a0cb39c367843a16e2 739 SUPERFAMILY SSF50249 169 200 8.39E-20 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS20765 fe10b341613263a0cb39c367843a16e2 739 SUPERFAMILY SSF50249 11 142 8.39E-20 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS20765 fe10b341613263a0cb39c367843a16e2 739 SUPERFAMILY SSF52540 204 481 4.24E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS20765 fe10b341613263a0cb39c367843a16e2 739 Gene3D G3DSA:3.40.50.300 488 678 2.0E-41 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS20765 fe10b341613263a0cb39c367843a16e2 739 Pfam PF00271 Helicase conserved C-terminal domain 555 629 3.8E-17 T 06-07-2017 IPR001650 Helicase, C-terminal BWK49_RS20765 fe10b341613263a0cb39c367843a16e2 739 Pfam PF00270 DEAD/DEAH box helicase 310 464 7.0E-18 T 06-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 BWK49_RS14985 cfaaefc554e9c18491425bf3f92758eb 140 Pfam PF03061 Thioesterase superfamily 47 126 3.0E-14 T 06-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 BWK49_RS14985 cfaaefc554e9c18491425bf3f92758eb 140 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 21 129 1.3E-21 T 06-07-2017 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-75105 BWK49_RS14985 cfaaefc554e9c18491425bf3f92758eb 140 SUPERFAMILY SSF54637 13 132 4.98E-29 T 06-07-2017 IPR029069 HotDog domain BWK49_RS14985 cfaaefc554e9c18491425bf3f92758eb 140 Gene3D G3DSA:3.10.129.10 15 136 2.1E-39 T 06-07-2017 IPR029069 HotDog domain BWK49_RS29105 5aa1d0184957754ffd9e5ce6180052b1 362 TIGRFAM TIGR00277 HDIG: HDIG domain 22 94 3.6E-8 T 06-07-2017 IPR006675 HDIG domain BWK49_RS29105 5aa1d0184957754ffd9e5ce6180052b1 362 Pfam PF01966 HD domain 21 121 1.3E-9 T 06-07-2017 IPR006674 HD domain BWK49_RS29105 5aa1d0184957754ffd9e5ce6180052b1 362 Gene3D G3DSA:1.10.3210.10 19 130 2.9E-11 T 06-07-2017 IPR006674 HD domain BWK49_RS29105 5aa1d0184957754ffd9e5ce6180052b1 362 SUPERFAMILY SSF109604 21 146 2.32E-15 T 06-07-2017 BWK49_RS03605 7099c843b9b27c28f46da3bf79cb9dc5 400 Pfam PF02470 MlaD protein 42 117 1.7E-13 T 06-07-2017 IPR003399 Mce/MlaD BWK49_RS03605 7099c843b9b27c28f46da3bf79cb9dc5 400 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 11 298 3.8E-76 T 06-07-2017 IPR005693 Virulence factor Mce protein BWK49_RS03605 7099c843b9b27c28f46da3bf79cb9dc5 400 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 146 389 3.4E-52 T 06-07-2017 IPR024516 Mammalian cell entry, C-terminal BWK49_RS03605 7099c843b9b27c28f46da3bf79cb9dc5 400 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 48 - T 06-07-2017 IPR010916 TonB box, conserved site BWK49_RS24695 6b22adad1afd008436adbdc0766868c8 1100 Gene3D G3DSA:3.40.50.300 322 452 9.7E-38 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS24695 6b22adad1afd008436adbdc0766868c8 1100 Gene3D G3DSA:3.40.50.300 597 725 9.7E-38 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS24695 6b22adad1afd008436adbdc0766868c8 1100 Gene3D G3DSA:1.10.486.10 456 596 3.6E-30 T 06-07-2017 BWK49_RS24695 6b22adad1afd008436adbdc0766868c8 1100 Gene3D G3DSA:3.90.320.10 768 1096 2.0E-73 T 06-07-2017 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 BWK49_RS24695 6b22adad1afd008436adbdc0766868c8 1100 SUPERFAMILY SSF52980 777 1094 6.43E-59 T 06-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 BWK49_RS24695 6b22adad1afd008436adbdc0766868c8 1100 Gene3D G3DSA:3.40.50.300 119 179 4.4E-51 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS24695 6b22adad1afd008436adbdc0766868c8 1100 Gene3D G3DSA:3.40.50.300 215 317 4.4E-51 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS24695 6b22adad1afd008436adbdc0766868c8 1100 Gene3D G3DSA:3.40.50.300 14 66 4.4E-51 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS24695 6b22adad1afd008436adbdc0766868c8 1100 Hamap MF_01485 RecBCD enzyme subunit RecB [recB]. 2 1094 16.225 T 06-07-2017 IPR004586 RecBCD enzyme subunit RecB GO:0005524|GO:0006281|GO:0008854 BWK49_RS24695 6b22adad1afd008436adbdc0766868c8 1100 Pfam PF00580 UvrD/REP helicase N-terminal domain 14 312 4.2E-51 T 06-07-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 BWK49_RS24695 6b22adad1afd008436adbdc0766868c8 1100 TIGRFAM TIGR00609 recB: exodeoxyribonuclease V, beta subunit 198 1093 6.4E-215 T 06-07-2017 IPR004586 RecBCD enzyme subunit RecB GO:0005524|GO:0006281|GO:0008854 BWK49_RS24695 6b22adad1afd008436adbdc0766868c8 1100 Pfam PF13361 UvrD-like helicase C-terminal domain 596 688 1.2E-7 T 06-07-2017 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 BWK49_RS24695 6b22adad1afd008436adbdc0766868c8 1100 Pfam PF12705 PD-(D/E)XK nuclease superfamily 830 1036 6.8E-6 T 06-07-2017 BWK49_RS24695 6b22adad1afd008436adbdc0766868c8 1100 SUPERFAMILY SSF52540 398 635 5.72E-86 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS24695 6b22adad1afd008436adbdc0766868c8 1100 SUPERFAMILY SSF52540 111 347 5.72E-86 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS24695 6b22adad1afd008436adbdc0766868c8 1100 SUPERFAMILY SSF52540 669 700 5.72E-86 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS24695 6b22adad1afd008436adbdc0766868c8 1100 SUPERFAMILY SSF52540 14 70 5.72E-86 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS19350 1cf45e6a26ea65e71d919a8bf46636de 126 Gene3D G3DSA:1.10.10.10 3 59 4.9E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS19350 1cf45e6a26ea65e71d919a8bf46636de 126 Pfam PF12802 MarR family 3 56 9.7E-9 T 06-07-2017 BWK49_RS19350 1cf45e6a26ea65e71d919a8bf46636de 126 SUPERFAMILY SSF46785 4 66 7.92E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS22780 a0c70eb737e36058c17c49e3c0eb7cbe 152 Pfam PF04073 Aminoacyl-tRNA editing domain 27 141 1.9E-21 T 06-07-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 BWK49_RS22780 a0c70eb737e36058c17c49e3c0eb7cbe 152 PIRSF PIRSF006181 2 152 2.9E-36 T 06-07-2017 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC BWK49_RS22780 a0c70eb737e36058c17c49e3c0eb7cbe 152 Gene3D G3DSA:3.90.960.10 5 151 1.7E-46 T 06-07-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 BWK49_RS22780 a0c70eb737e36058c17c49e3c0eb7cbe 152 SUPERFAMILY SSF55826 7 149 9.16E-36 T 06-07-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 BWK49_RS27450 9d32627cc2fe42bc03ae23a22f1147b0 406 Gene3D G3DSA:1.20.140.10 230 396 5.4E-51 T 06-07-2017 BWK49_RS27450 9d32627cc2fe42bc03ae23a22f1147b0 406 Gene3D G3DSA:1.10.540.10 2 126 4.0E-26 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS27450 9d32627cc2fe42bc03ae23a22f1147b0 406 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 128 228 3.9E-20 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 BWK49_RS27450 9d32627cc2fe42bc03ae23a22f1147b0 406 SUPERFAMILY SSF56645 8 253 1.22E-63 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS27450 9d32627cc2fe42bc03ae23a22f1147b0 406 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 240 390 4.9E-38 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS27450 9d32627cc2fe42bc03ae23a22f1147b0 406 SUPERFAMILY SSF47203 238 395 3.54E-44 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS27450 9d32627cc2fe42bc03ae23a22f1147b0 406 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 124 5.3E-9 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS27450 9d32627cc2fe42bc03ae23a22f1147b0 406 Gene3D G3DSA:2.40.110.10 127 229 5.4E-42 T 06-07-2017 BWK49_RS02935 3debe8fbd8a089b9df7885e9477ecd50 945 Gene3D G3DSA:1.10.460.10 163 210 3.9E-50 T 06-07-2017 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 BWK49_RS02935 3debe8fbd8a089b9df7885e9477ecd50 945 Gene3D G3DSA:1.10.460.10 511 605 3.9E-50 T 06-07-2017 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 BWK49_RS02935 3debe8fbd8a089b9df7885e9477ecd50 945 Pfam PF01751 Toprim domain 20 141 7.6E-28 T 06-07-2017 IPR006171 Toprim domain BWK49_RS02935 3debe8fbd8a089b9df7885e9477ecd50 945 SMART SM00493 18 132 1.6E-37 T 06-07-2017 IPR006171 Toprim domain BWK49_RS02935 3debe8fbd8a089b9df7885e9477ecd50 945 Pfam PF13368 Topoisomerase C-terminal repeat 715 794 1.5E-11 T 06-07-2017 IPR025589 Topoisomerase C-terminal repeat BWK49_RS02935 3debe8fbd8a089b9df7885e9477ecd50 945 Pfam PF13368 Topoisomerase C-terminal repeat 866 918 1.5E-21 T 06-07-2017 IPR025589 Topoisomerase C-terminal repeat BWK49_RS02935 3debe8fbd8a089b9df7885e9477ecd50 945 Pfam PF13368 Topoisomerase C-terminal repeat 647 708 1.4E-5 T 06-07-2017 IPR025589 Topoisomerase C-terminal repeat BWK49_RS02935 3debe8fbd8a089b9df7885e9477ecd50 945 Pfam PF13368 Topoisomerase C-terminal repeat 799 852 3.9E-18 T 06-07-2017 IPR025589 Topoisomerase C-terminal repeat BWK49_RS02935 3debe8fbd8a089b9df7885e9477ecd50 945 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 337 346 2.7E-34 T 06-07-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 BWK49_RS02935 3debe8fbd8a089b9df7885e9477ecd50 945 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 106 119 2.7E-34 T 06-07-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 BWK49_RS02935 3debe8fbd8a089b9df7885e9477ecd50 945 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 190 208 2.7E-34 T 06-07-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 BWK49_RS02935 3debe8fbd8a089b9df7885e9477ecd50 945 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 416 432 2.7E-34 T 06-07-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 BWK49_RS02935 3debe8fbd8a089b9df7885e9477ecd50 945 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 527 541 2.7E-34 T 06-07-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 BWK49_RS02935 3debe8fbd8a089b9df7885e9477ecd50 945 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 20 666 4.0E-261 T 06-07-2017 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 BWK49_RS02935 3debe8fbd8a089b9df7885e9477ecd50 945 Gene3D G3DSA:3.40.50.140 18 162 8.0E-47 T 06-07-2017 IPR006171 Toprim domain BWK49_RS02935 3debe8fbd8a089b9df7885e9477ecd50 945 SMART SM00436 132 220 8.0E-48 T 06-07-2017 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 BWK49_RS02935 3debe8fbd8a089b9df7885e9477ecd50 945 Gene3D G3DSA:2.70.20.10 212 361 1.1E-26 T 06-07-2017 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 BWK49_RS02935 3debe8fbd8a089b9df7885e9477ecd50 945 Gene3D G3DSA:2.70.20.10 364 510 8.3E-31 T 06-07-2017 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 BWK49_RS02935 3debe8fbd8a089b9df7885e9477ecd50 945 SMART SM00437 295 564 2.0E-129 T 06-07-2017 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 BWK49_RS02935 3debe8fbd8a089b9df7885e9477ecd50 945 SUPERFAMILY SSF56712 18 605 2.62E-177 T 06-07-2017 IPR023405 DNA topoisomerase, type IA, core domain BWK49_RS02935 3debe8fbd8a089b9df7885e9477ecd50 945 Hamap MF_00952 DNA topoisomerase 1 [topA]. 18 811 55.169 T 06-07-2017 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 BWK49_RS02935 3debe8fbd8a089b9df7885e9477ecd50 945 Pfam PF01131 DNA topoisomerase 156 601 5.2E-119 T 06-07-2017 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 BWK49_RS02935 3debe8fbd8a089b9df7885e9477ecd50 945 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 332 346 - T 06-07-2017 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 BWK49_RS07015 dc8379039704d267d3bd869d580bb611 104 Pfam PF08310 LGFP repeat 15 64 1.1E-12 T 06-07-2017 IPR013207 LGFP BWK49_RS07015 dc8379039704d267d3bd869d580bb611 104 Pfam PF08310 LGFP repeat 66 100 1.9E-7 T 06-07-2017 IPR013207 LGFP BWK49_RS08670 753c8e05b6b00e03e44c799db8940c93 193 Gene3D G3DSA:1.10.357.10 9 173 9.6E-27 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS08670 753c8e05b6b00e03e44c799db8940c93 193 SUPERFAMILY SSF46689 10 80 5.2E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS08670 753c8e05b6b00e03e44c799db8940c93 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 2.4E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS08670 753c8e05b6b00e03e44c799db8940c93 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 2.4E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS08670 753c8e05b6b00e03e44c799db8940c93 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 63 1.0E-13 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS02130 3fa6625ab8263e4702ae64358de2a926 427 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 134 221 3.1E-18 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 BWK49_RS02130 3fa6625ab8263e4702ae64358de2a926 427 Gene3D G3DSA:1.10.540.10 4 131 6.0E-27 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS02130 3fa6625ab8263e4702ae64358de2a926 427 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 11 130 7.8E-16 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS02130 3fa6625ab8263e4702ae64358de2a926 427 Gene3D G3DSA:2.40.110.10 133 235 3.3E-31 T 06-07-2017 BWK49_RS02130 3fa6625ab8263e4702ae64358de2a926 427 Gene3D G3DSA:1.20.140.10 236 399 7.0E-37 T 06-07-2017 BWK49_RS02130 3fa6625ab8263e4702ae64358de2a926 427 SUPERFAMILY SSF56645 3 257 5.89E-63 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS02130 3fa6625ab8263e4702ae64358de2a926 427 SUPERFAMILY SSF47203 242 398 2.26E-36 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS02130 3fa6625ab8263e4702ae64358de2a926 427 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 244 394 1.2E-26 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS24215 93d66a10722ef7363fcd2eed3e471557 147 ProSitePatterns PS00475 Ribosomal protein L15 signature. 110 140 - T 06-07-2017 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 BWK49_RS24215 93d66a10722ef7363fcd2eed3e471557 147 Gene3D G3DSA:3.100.10.10 33 146 3.5E-34 T 06-07-2017 BWK49_RS24215 93d66a10722ef7363fcd2eed3e471557 147 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 4 143 2.2E-47 T 06-07-2017 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS24215 93d66a10722ef7363fcd2eed3e471557 147 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 5 146 19.494 T 06-07-2017 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 BWK49_RS24215 93d66a10722ef7363fcd2eed3e471557 147 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 28 144 3.3E-32 T 06-07-2017 IPR021131 Ribosomal protein L18e/L15P BWK49_RS24215 93d66a10722ef7363fcd2eed3e471557 147 SUPERFAMILY SSF52080 6 144 5.63E-40 T 06-07-2017 IPR021131 Ribosomal protein L18e/L15P BWK49_RS19355 3cd6e283924dae274409e671d4d8878c 398 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 255 398 7.3E-12 T 06-07-2017 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 BWK49_RS19355 3cd6e283924dae274409e671d4d8878c 398 SUPERFAMILY SSF53335 67 398 1.28E-36 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS19355 3cd6e283924dae274409e671d4d8878c 398 Gene3D G3DSA:2.40.50.140 7 77 2.1E-20 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS19355 3cd6e283924dae274409e671d4d8878c 398 SUPERFAMILY SSF50249 9 63 3.37E-12 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS19355 3cd6e283924dae274409e671d4d8878c 398 Pfam PF01938 TRAM domain 15 58 3.9E-7 T 06-07-2017 IPR002792 TRAM domain BWK49_RS19355 3cd6e283924dae274409e671d4d8878c 398 Gene3D G3DSA:3.40.50.150 201 398 2.2E-36 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS04100 ce6bb9d93c466f576a2a8ddfb46c4bac 277 SUPERFAMILY SSF52821 159 275 2.23E-36 T 06-07-2017 IPR001763 Rhodanese-like domain BWK49_RS04100 ce6bb9d93c466f576a2a8ddfb46c4bac 277 ProSitePatterns PS00380 Rhodanese signature 1. 34 45 - T 06-07-2017 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 BWK49_RS04100 ce6bb9d93c466f576a2a8ddfb46c4bac 277 Gene3D G3DSA:3.40.250.10 159 274 2.0E-37 T 06-07-2017 IPR001763 Rhodanese-like domain BWK49_RS04100 ce6bb9d93c466f576a2a8ddfb46c4bac 277 ProSitePatterns PS00683 Rhodanese C-terminal signature. 255 265 - T 06-07-2017 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 BWK49_RS04100 ce6bb9d93c466f576a2a8ddfb46c4bac 277 SMART SM00450 144 271 7.7E-25 T 06-07-2017 IPR001763 Rhodanese-like domain BWK49_RS04100 ce6bb9d93c466f576a2a8ddfb46c4bac 277 SMART SM00450 8 122 6.4E-22 T 06-07-2017 IPR001763 Rhodanese-like domain BWK49_RS04100 ce6bb9d93c466f576a2a8ddfb46c4bac 277 SUPERFAMILY SSF52821 3 138 2.23E-36 T 06-07-2017 IPR001763 Rhodanese-like domain BWK49_RS04100 ce6bb9d93c466f576a2a8ddfb46c4bac 277 Pfam PF00581 Rhodanese-like domain 150 266 1.1E-18 T 06-07-2017 IPR001763 Rhodanese-like domain BWK49_RS04100 ce6bb9d93c466f576a2a8ddfb46c4bac 277 Pfam PF00581 Rhodanese-like domain 9 118 2.9E-17 T 06-07-2017 IPR001763 Rhodanese-like domain BWK49_RS04100 ce6bb9d93c466f576a2a8ddfb46c4bac 277 Gene3D G3DSA:3.40.250.10 2 138 1.2E-38 T 06-07-2017 IPR001763 Rhodanese-like domain BWK49_RS01745 e516d2e1c9f37f3e00e04d7f1c916c88 172 Gene3D G3DSA:3.10.450.50 10 172 2.6E-63 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS01745 e516d2e1c9f37f3e00e04d7f1c916c88 172 SUPERFAMILY SSF54427 9 172 5.18E-51 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS01745 e516d2e1c9f37f3e00e04d7f1c916c88 172 Pfam PF00866 Ring hydroxylating beta subunit 22 163 1.2E-45 T 06-07-2017 IPR000391 Ring-hydroxylating dioxygenase beta subunit GO:0003824|GO:0006725|GO:0055114 BWK49_RS22465 44523a8f5041907f4aa04392f8a0d36f 166 PIRSF PIRSF005900 7 166 3.1E-39 T 06-07-2017 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 BWK49_RS22465 44523a8f5041907f4aa04392f8a0d36f 166 ProSitePatterns PS00818 Dps protein family signature 1. 46 62 - T 06-07-2017 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 BWK49_RS22465 44523a8f5041907f4aa04392f8a0d36f 166 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 141 159 8.3E-12 T 06-07-2017 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 BWK49_RS22465 44523a8f5041907f4aa04392f8a0d36f 166 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 46 62 8.3E-12 T 06-07-2017 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 BWK49_RS22465 44523a8f5041907f4aa04392f8a0d36f 166 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 70 86 8.3E-12 T 06-07-2017 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 BWK49_RS22465 44523a8f5041907f4aa04392f8a0d36f 166 Gene3D G3DSA:1.20.1260.10 19 161 1.9E-42 T 06-07-2017 IPR012347 Ferritin-related BWK49_RS22465 44523a8f5041907f4aa04392f8a0d36f 166 SUPERFAMILY SSF47240 18 161 1.28E-43 T 06-07-2017 IPR009078 Ferritin-like superfamily BWK49_RS22465 44523a8f5041907f4aa04392f8a0d36f 166 Pfam PF00210 Ferritin-like domain 27 161 2.0E-21 T 06-07-2017 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 BWK49_RS09985 e1c1c23547a9aa1c0a68a7cd71020061 939 Pfam PF10150 Ribonuclease E/G family 447 728 5.7E-101 T 06-07-2017 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 BWK49_RS09985 e1c1c23547a9aa1c0a68a7cd71020061 939 SUPERFAMILY SSF50249 368 451 4.61E-16 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS09985 e1c1c23547a9aa1c0a68a7cd71020061 939 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 343 756 8.1E-157 T 06-07-2017 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 BWK49_RS09985 e1c1c23547a9aa1c0a68a7cd71020061 939 SMART SM00316 366 445 3.7E-9 T 06-07-2017 IPR022967 RNA-binding domain, S1 BWK49_RS09985 e1c1c23547a9aa1c0a68a7cd71020061 939 Gene3D G3DSA:2.40.50.140 361 451 4.7E-28 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS03430 08e974f288bfd042bdf387667ef6f7c9 393 Gene3D G3DSA:3.40.47.10 14 116 7.7E-14 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS03430 08e974f288bfd042bdf387667ef6f7c9 393 Gene3D G3DSA:3.40.47.10 210 237 7.7E-14 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS03430 08e974f288bfd042bdf387667ef6f7c9 393 SUPERFAMILY SSF53901 268 385 3.31E-13 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS03430 08e974f288bfd042bdf387667ef6f7c9 393 SUPERFAMILY SSF53901 8 240 1.34E-22 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS03430 08e974f288bfd042bdf387667ef6f7c9 393 PIRSF PIRSF000429 5 346 8.1E-22 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 BWK49_RS05225 5c04c4c3b821617017f9a09a2ad57652 507 SUPERFAMILY SSF51905 9 224 3.31E-50 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS05225 5c04c4c3b821617017f9a09a2ad57652 507 Gene3D G3DSA:3.50.50.60 304 344 6.1E-8 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS05225 5c04c4c3b821617017f9a09a2ad57652 507 Gene3D G3DSA:3.50.50.60 181 223 6.1E-8 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS05225 5c04c4c3b821617017f9a09a2ad57652 507 SUPERFAMILY SSF51905 284 464 8.42E-18 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS05225 5c04c4c3b821617017f9a09a2ad57652 507 Gene3D G3DSA:3.50.50.60 387 483 3.8E-65 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS05225 5c04c4c3b821617017f9a09a2ad57652 507 Gene3D G3DSA:3.50.50.60 6 180 3.8E-65 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS05225 5c04c4c3b821617017f9a09a2ad57652 507 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 12 208 2.5E-18 T 06-07-2017 BWK49_RS14970 cbb13e38d8892064d524ff8c80702ed9 305 TIGRFAM TIGR03560 F420_Rv1855c: probable F420-dependent oxidoreductase, Rv1855c family 11 233 3.2E-89 T 06-07-2017 IPR019952 F420-dependent oxidoreductase-predicted, Rv1855c BWK49_RS14970 cbb13e38d8892064d524ff8c80702ed9 305 Gene3D G3DSA:3.20.20.30 3 303 4.0E-73 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS14970 cbb13e38d8892064d524ff8c80702ed9 305 SUPERFAMILY SSF51679 3 303 1.7E-69 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS14970 cbb13e38d8892064d524ff8c80702ed9 305 Pfam PF00296 Luciferase-like monooxygenase 18 242 2.0E-46 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS14585 8025ad8697e707f38ad0677eaebab884 213 Pfam PF01161 Phosphatidylethanolamine-binding protein 84 211 8.6E-23 T 06-07-2017 IPR008914 Phosphatidylethanolamine-binding protein BWK49_RS14585 8025ad8697e707f38ad0677eaebab884 213 Gene3D G3DSA:3.90.280.10 70 211 1.1E-37 T 06-07-2017 IPR008914 Phosphatidylethanolamine-binding protein BWK49_RS14585 8025ad8697e707f38ad0677eaebab884 213 SUPERFAMILY SSF49777 71 211 2.49E-34 T 06-07-2017 IPR008914 Phosphatidylethanolamine-binding protein BWK49_RS22810 dcae79015e162adeffd1b10257e9735a 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 6.3E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS22810 dcae79015e162adeffd1b10257e9735a 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 6.3E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS22810 dcae79015e162adeffd1b10257e9735a 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 6.3E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS22810 dcae79015e162adeffd1b10257e9735a 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 6.3E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS22810 dcae79015e162adeffd1b10257e9735a 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 6.3E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS22810 dcae79015e162adeffd1b10257e9735a 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 6.3E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS22810 dcae79015e162adeffd1b10257e9735a 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 252 1.1E-58 T 06-07-2017 BWK49_RS22810 dcae79015e162adeffd1b10257e9735a 256 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 148 176 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS22810 dcae79015e162adeffd1b10257e9735a 256 Gene3D G3DSA:3.40.50.720 6 255 1.6E-73 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS22810 dcae79015e162adeffd1b10257e9735a 256 SUPERFAMILY SSF51735 8 255 3.28E-71 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS20140 b3b377d4afde832e1425c5c4215d821b 192 ProDom PD886639 ANTIGEN IMMUNOGENIC EXTRACELLULAR MPT63 MPB63 PRECURSOR IMMUNOPROTECTIVE SIGNAL SEQUENCING DIRECT 33 158 8.0E-60 T 06-07-2017 IPR015250 MPT63-like GO:0005615 BWK49_RS20140 b3b377d4afde832e1425c5c4215d821b 192 Gene3D G3DSA:2.60.40.1240 32 157 1.1E-53 T 06-07-2017 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain BWK49_RS20140 b3b377d4afde832e1425c5c4215d821b 192 SUPERFAMILY SSF81982 32 157 4.05E-48 T 06-07-2017 IPR015250 MPT63-like GO:0005615 BWK49_RS20140 b3b377d4afde832e1425c5c4215d821b 192 Pfam PF09167 Domain of unknown function (DUF1942) 33 156 2.3E-47 T 06-07-2017 IPR015250 MPT63-like GO:0005615 BWK49_RS25180 06119dece671e05f614837b8583e8a46 394 SUPERFAMILY SSF51604 150 383 1.15E-51 T 06-07-2017 IPR029065 Enolase C-terminal domain-like BWK49_RS25180 06119dece671e05f614837b8583e8a46 394 SMART SM00922 165 262 1.5E-19 T 06-07-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal BWK49_RS25180 06119dece671e05f614837b8583e8a46 394 Gene3D G3DSA:3.20.20.120 127 380 5.7E-56 T 06-07-2017 IPR029065 Enolase C-terminal domain-like BWK49_RS25180 06119dece671e05f614837b8583e8a46 394 Gene3D G3DSA:3.30.390.10 21 126 7.7E-30 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 BWK49_RS25180 06119dece671e05f614837b8583e8a46 394 SUPERFAMILY SSF54826 2 140 4.09E-16 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 BWK49_RS25180 06119dece671e05f614837b8583e8a46 394 Pfam PF13378 Enolase C-terminal domain-like 168 377 3.4E-39 T 06-07-2017 IPR029065 Enolase C-terminal domain-like BWK49_RS20190 13334eda1baa894bf5330f78974f062c 467 Pfam PF01425 Amidase 33 449 1.4E-99 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 BWK49_RS20190 13334eda1baa894bf5330f78974f062c 467 ProSitePatterns PS00571 Amidases signature. 153 184 - T 06-07-2017 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 BWK49_RS20190 13334eda1baa894bf5330f78974f062c 467 SUPERFAMILY SSF75304 8 458 2.88E-104 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 BWK49_RS20190 13334eda1baa894bf5330f78974f062c 467 Gene3D G3DSA:3.90.1300.10 10 463 7.2E-96 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 BWK49_RS17495 7e6e992a1bc168772d65c61b6e713a58 145 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 32 142 3.4E-41 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 BWK49_RS17495 7e6e992a1bc168772d65c61b6e713a58 145 Pfam PF04075 Domain of unknown function (DUF385) 14 143 4.1E-55 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 BWK49_RS17495 7e6e992a1bc168772d65c61b6e713a58 145 SUPERFAMILY SSF50475 36 143 1.3E-6 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 BWK49_RS26510 daea82a55d5c41834030334cbcdfff31 302 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 39 268 3.7E-48 T 06-07-2017 IPR018713 Domain of unknown function DUF2236 BWK49_RS25315 68eeb8ae8284083547a1a0193bded53b 375 SUPERFAMILY SSF51735 23 336 5.76E-41 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS25315 68eeb8ae8284083547a1a0193bded53b 375 Pfam PF01370 NAD dependent epimerase/dehydratase family 25 207 2.0E-20 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 BWK49_RS25315 68eeb8ae8284083547a1a0193bded53b 375 Gene3D G3DSA:3.40.50.720 25 335 2.7E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS25295 f83f3a7cce38bf7157eacd0f37f8cc70 303 Gene3D G3DSA:3.40.50.1000 126 272 6.2E-50 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS25295 f83f3a7cce38bf7157eacd0f37f8cc70 303 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 53 254 4.5E-57 T 06-07-2017 IPR006385 HAD-superfamily hydrolase, subfamily IB, PSPase-like, bacterial BWK49_RS25295 f83f3a7cce38bf7157eacd0f37f8cc70 303 Pfam PF12710 haloacid dehalogenase-like hydrolase 54 240 3.1E-28 T 06-07-2017 BWK49_RS25295 f83f3a7cce38bf7157eacd0f37f8cc70 303 SUPERFAMILY SSF56784 53 274 3.07E-30 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS25295 f83f3a7cce38bf7157eacd0f37f8cc70 303 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 53 243 8.8E-17 T 06-07-2017 IPR006383 HAD-superfamily hydrolase, subfamily IB, PSPase-like GO:0008152|GO:0016791 BWK49_RS02985 77066b17005d4560e762d61d7b9ce79e 162 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 52 58 - T 06-07-2017 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 BWK49_RS02985 77066b17005d4560e762d61d7b9ce79e 162 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 1 158 34.133 T 06-07-2017 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 BWK49_RS02985 77066b17005d4560e762d61d7b9ce79e 162 Pfam PF00719 Inorganic pyrophosphatase 5 158 8.1E-52 T 06-07-2017 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 BWK49_RS02985 77066b17005d4560e762d61d7b9ce79e 162 SUPERFAMILY SSF50324 3 159 7.06E-58 T 06-07-2017 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 BWK49_RS02985 77066b17005d4560e762d61d7b9ce79e 162 Gene3D G3DSA:3.90.80.10 2 159 5.5E-53 T 06-07-2017 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 BWK49_RS14840 770c5a8ba74e32c6f11cd21a768eb2aa 442 Gene3D G3DSA:3.20.20.80 8 358 6.5E-80 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 BWK49_RS14840 770c5a8ba74e32c6f11cd21a768eb2aa 442 SMART SM00642 18 357 1.4E-41 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 BWK49_RS14840 770c5a8ba74e32c6f11cd21a768eb2aa 442 SUPERFAMILY SSF51011 374 439 1.68E-6 T 06-07-2017 BWK49_RS14840 770c5a8ba74e32c6f11cd21a768eb2aa 442 Pfam PF00128 Alpha amylase, catalytic domain 142 318 3.9E-23 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 BWK49_RS14840 770c5a8ba74e32c6f11cd21a768eb2aa 442 Pfam PF00128 Alpha amylase, catalytic domain 49 137 2.7E-20 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 BWK49_RS14840 770c5a8ba74e32c6f11cd21a768eb2aa 442 Pfam PF11941 Domain of unknown function (DUF3459) 349 434 1.2E-5 T 06-07-2017 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) BWK49_RS14840 770c5a8ba74e32c6f11cd21a768eb2aa 442 SUPERFAMILY SSF51445 8 364 3.52E-77 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily BWK49_RS14840 770c5a8ba74e32c6f11cd21a768eb2aa 442 Gene3D G3DSA:2.60.40.1180 371 439 9.6E-8 T 06-07-2017 IPR013780 Glycosyl hydrolase, all-beta BWK49_RS18010 0e91d7980484f1dabfbac6723fe67156 327 PIRSF PIRSF005739 1 326 1.4E-49 T 06-07-2017 IPR016461 O-methyltransferase COMT-type GO:0008168 BWK49_RS18010 0e91d7980484f1dabfbac6723fe67156 327 Pfam PF16864 Dimerisation domain 2 78 2.7E-10 T 06-07-2017 IPR031725 Acetylserotonin O-methyltransferase, dimerisation domain BWK49_RS18010 0e91d7980484f1dabfbac6723fe67156 327 Gene3D G3DSA:3.40.50.150 85 325 5.6E-68 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS18010 0e91d7980484f1dabfbac6723fe67156 327 Gene3D G3DSA:1.10.10.10 1 84 4.8E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS18010 0e91d7980484f1dabfbac6723fe67156 327 SUPERFAMILY SSF53335 82 311 5.4E-49 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS18010 0e91d7980484f1dabfbac6723fe67156 327 Pfam PF00891 O-methyltransferase 95 310 4.6E-50 T 06-07-2017 IPR001077 O-methyltransferase, family 2 GO:0008171 BWK49_RS18010 0e91d7980484f1dabfbac6723fe67156 327 SUPERFAMILY SSF46785 2 81 1.43E-10 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS19790 7bfb82530277e77a5b33d1f71905f8ba 485 Pfam PF00743 Flavin-binding monooxygenase-like 8 337 6.7E-20 T 06-07-2017 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 BWK49_RS19790 7bfb82530277e77a5b33d1f71905f8ba 485 SUPERFAMILY SSF51905 4 251 3.24E-58 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS19790 7bfb82530277e77a5b33d1f71905f8ba 485 Gene3D G3DSA:3.50.50.60 293 461 2.0E-14 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS19790 7bfb82530277e77a5b33d1f71905f8ba 485 Gene3D G3DSA:3.50.50.60 5 214 3.2E-62 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS19790 7bfb82530277e77a5b33d1f71905f8ba 485 PRINTS PR00419 Adrenodoxin reductase family signature 7 29 1.9E-7 T 06-07-2017 BWK49_RS19790 7bfb82530277e77a5b33d1f71905f8ba 485 PRINTS PR00419 Adrenodoxin reductase family signature 31 44 1.9E-7 T 06-07-2017 BWK49_RS19790 7bfb82530277e77a5b33d1f71905f8ba 485 SUPERFAMILY SSF51905 264 456 1.11E-21 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS12320 53add28d5b2cab553a87b91f2ebdeb52 198 Gene3D G3DSA:1.10.357.10 5 181 8.3E-21 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS12320 53add28d5b2cab553a87b91f2ebdeb52 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 54 3.0E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS12320 53add28d5b2cab553a87b91f2ebdeb52 198 SUPERFAMILY SSF46689 10 70 9.75E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS01785 f0b4ac65b79abba9e8f3d45da466c600 457 ProSitePatterns PS00570 Bacterial ring hydroxylating dioxygenases alpha-subunit signature. 80 103 - T 06-07-2017 IPR015881 Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site GO:0005506|GO:0016705|GO:0051537|GO:0055114 BWK49_RS01785 f0b4ac65b79abba9e8f3d45da466c600 457 SUPERFAMILY SSF50022 7 155 5.5E-46 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS01785 f0b4ac65b79abba9e8f3d45da466c600 457 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 172 437 6.1E-16 T 06-07-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 BWK49_RS01785 f0b4ac65b79abba9e8f3d45da466c600 457 Gene3D G3DSA:2.102.10.10 24 138 3.1E-17 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS01785 f0b4ac65b79abba9e8f3d45da466c600 457 SUPERFAMILY SSF55961 157 440 2.98E-52 T 06-07-2017 BWK49_RS01785 f0b4ac65b79abba9e8f3d45da466c600 457 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 73 93 2.8E-38 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS01785 f0b4ac65b79abba9e8f3d45da466c600 457 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 140 166 2.8E-38 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS01785 f0b4ac65b79abba9e8f3d45da466c600 457 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 22 47 2.8E-38 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS01785 f0b4ac65b79abba9e8f3d45da466c600 457 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 94 114 2.8E-38 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS01785 f0b4ac65b79abba9e8f3d45da466c600 457 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 52 67 2.8E-38 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS01785 f0b4ac65b79abba9e8f3d45da466c600 457 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 180 202 2.8E-38 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS01785 f0b4ac65b79abba9e8f3d45da466c600 457 Gene3D G3DSA:3.90.380.10 139 441 1.6E-90 T 06-07-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 BWK49_RS01785 f0b4ac65b79abba9e8f3d45da466c600 457 Pfam PF00355 Rieske [2Fe-2S] domain 37 121 3.3E-18 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS08965 933509778f92dc4e229057ea475218d7 304 PRINTS PR00126 ATP synthase gamma subunit signature 74 93 1.1E-34 T 06-07-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 BWK49_RS08965 933509778f92dc4e229057ea475218d7 304 PRINTS PR00126 ATP synthase gamma subunit signature 179 196 1.1E-34 T 06-07-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 BWK49_RS08965 933509778f92dc4e229057ea475218d7 304 PRINTS PR00126 ATP synthase gamma subunit signature 278 299 1.1E-34 T 06-07-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 BWK49_RS08965 933509778f92dc4e229057ea475218d7 304 PRINTS PR00126 ATP synthase gamma subunit signature 247 266 1.1E-34 T 06-07-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 BWK49_RS08965 933509778f92dc4e229057ea475218d7 304 SUPERFAMILY SSF52943 3 300 2.35E-80 T 06-07-2017 IPR023633 ATPase, F1 complex, gamma subunit domain Reactome: R-HSA-163210 BWK49_RS08965 933509778f92dc4e229057ea475218d7 304 Pfam PF00231 ATP synthase 4 300 9.9E-87 T 06-07-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 BWK49_RS08965 933509778f92dc4e229057ea475218d7 304 Hamap MF_00815 ATP synthase gamma chain [atpG]. 2 300 34.247 T 06-07-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 BWK49_RS08965 933509778f92dc4e229057ea475218d7 304 Gene3D G3DSA:1.10.287.80 249 295 3.0E-26 T 06-07-2017 BWK49_RS08965 933509778f92dc4e229057ea475218d7 304 Gene3D G3DSA:3.40.1380.10 64 204 6.9E-41 T 06-07-2017 BWK49_RS08965 933509778f92dc4e229057ea475218d7 304 Gene3D G3DSA:1.10.287.80 20 61 1.3E-26 T 06-07-2017 BWK49_RS08965 933509778f92dc4e229057ea475218d7 304 Gene3D G3DSA:1.10.287.80 215 248 1.3E-26 T 06-07-2017 BWK49_RS08965 933509778f92dc4e229057ea475218d7 304 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 286 299 - T 06-07-2017 IPR023632 ATPase, F1 complex, gamma subunit conserved site Reactome: R-HSA-163210 BWK49_RS08965 933509778f92dc4e229057ea475218d7 304 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 3 300 1.6E-108 T 06-07-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 BWK49_RS25400 770bdbe840bd63b28a13c670a55ee910 444 Gene3D G3DSA:2.40.440.10 250 369 3.0E-15 T 06-07-2017 BWK49_RS25400 770bdbe840bd63b28a13c670a55ee910 444 Pfam PF03734 L,D-transpeptidase catalytic domain 251 369 1.9E-13 T 06-07-2017 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 BWK49_RS25400 770bdbe840bd63b28a13c670a55ee910 444 SUPERFAMILY SSF141523 248 369 8.76E-22 T 06-07-2017 BWK49_RS25135 eb065992ea1479f4b41706bea18255d2 427 Gene3D G3DSA:3.40.50.300 175 410 7.3E-32 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS25135 eb065992ea1479f4b41706bea18255d2 427 SUPERFAMILY SSF52540 175 410 8.25E-31 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS25135 eb065992ea1479f4b41706bea18255d2 427 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 176 357 1.8E-12 T 06-07-2017 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain BWK49_RS09885 7978702253725c7ae1effaf07acb5eb5 268 SUPERFAMILY SSF57716 232 268 1.76E-12 T 06-07-2017 BWK49_RS09885 7978702253725c7ae1effaf07acb5eb5 268 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 126 213 2.7E-22 T 06-07-2017 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 BWK49_RS09885 7978702253725c7ae1effaf07acb5eb5 268 Gene3D G3DSA:3.20.190.10 2 126 2.1E-12 T 06-07-2017 BWK49_RS09885 7978702253725c7ae1effaf07acb5eb5 268 SUPERFAMILY SSF81624 2 127 3.66E-23 T 06-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 BWK49_RS09885 7978702253725c7ae1effaf07acb5eb5 268 SMART SM00898 2 112 4.0E-15 T 06-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 BWK49_RS09885 7978702253725c7ae1effaf07acb5eb5 268 SUPERFAMILY SSF46946 125 209 9.71E-25 T 06-07-2017 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 BWK49_RS09885 7978702253725c7ae1effaf07acb5eb5 268 Pfam PF06827 Zinc finger found in FPG and IleRS 240 268 5.6E-9 T 06-07-2017 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 BWK49_RS09885 7978702253725c7ae1effaf07acb5eb5 268 SMART SM01232 126 218 1.7E-32 T 06-07-2017 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 BWK49_RS09885 7978702253725c7ae1effaf07acb5eb5 268 ProSitePatterns PS01242 Zinc finger FPG-type signature. 243 267 - T 06-07-2017 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 BWK49_RS09885 7978702253725c7ae1effaf07acb5eb5 268 Gene3D G3DSA:1.10.8.50 127 268 6.9E-46 T 06-07-2017 BWK49_RS13055 6a79395266d9b9d77494ac1ff27991a3 376 SUPERFAMILY SSF51905 4 169 5.48E-51 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS13055 6a79395266d9b9d77494ac1ff27991a3 376 SUPERFAMILY SSF51905 267 364 5.48E-51 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS13055 6a79395266d9b9d77494ac1ff27991a3 376 Gene3D G3DSA:3.50.50.60 268 342 1.1E-33 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS13055 6a79395266d9b9d77494ac1ff27991a3 376 Gene3D G3DSA:3.50.50.60 3 175 1.1E-33 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS13055 6a79395266d9b9d77494ac1ff27991a3 376 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 1.0E-14 T 06-07-2017 BWK49_RS13055 6a79395266d9b9d77494ac1ff27991a3 376 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 280 295 1.0E-14 T 06-07-2017 BWK49_RS13055 6a79395266d9b9d77494ac1ff27991a3 376 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 295 311 1.0E-14 T 06-07-2017 BWK49_RS13055 6a79395266d9b9d77494ac1ff27991a3 376 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 148 163 1.0E-14 T 06-07-2017 BWK49_RS13055 6a79395266d9b9d77494ac1ff27991a3 376 Pfam PF01494 FAD binding domain 5 317 4.9E-17 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 BWK49_RS03550 f7b77a40eb916b8550b5d6937f3e8a14 274 Pfam PF04909 Amidohydrolase 36 270 2.5E-43 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 BWK49_RS03550 f7b77a40eb916b8550b5d6937f3e8a14 274 Gene3D G3DSA:3.20.20.140 4 271 3.3E-65 T 06-07-2017 BWK49_RS03550 f7b77a40eb916b8550b5d6937f3e8a14 274 SUPERFAMILY SSF51556 4 270 7.78E-63 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS08915 8a2d03f46ce5236132e3fe410f279cc3 357 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 229 245 - T 06-07-2017 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 BWK49_RS08915 8a2d03f46ce5236132e3fe410f279cc3 357 Pfam PF00472 RF-1 domain 215 322 1.0E-39 T 06-07-2017 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 BWK49_RS08915 8a2d03f46ce5236132e3fe410f279cc3 357 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 4 357 35.23 T 06-07-2017 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 BWK49_RS08915 8a2d03f46ce5236132e3fe410f279cc3 357 Gene3D G3DSA:1.20.58.410 8 88 7.1E-15 T 06-07-2017 BWK49_RS08915 8a2d03f46ce5236132e3fe410f279cc3 357 Gene3D G3DSA:3.30.160.20 215 286 5.9E-34 T 06-07-2017 IPR014720 Double-stranded RNA-binding domain BWK49_RS08915 8a2d03f46ce5236132e3fe410f279cc3 357 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 5 356 1.6E-148 T 06-07-2017 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 BWK49_RS08915 8a2d03f46ce5236132e3fe410f279cc3 357 Pfam PF03462 PCRF domain 13 204 5.8E-62 T 06-07-2017 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 BWK49_RS08915 8a2d03f46ce5236132e3fe410f279cc3 357 SMART SM00937 66 179 3.9E-46 T 06-07-2017 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 BWK49_RS08915 8a2d03f46ce5236132e3fe410f279cc3 357 SUPERFAMILY SSF75620 11 354 1.06E-121 T 06-07-2017 BWK49_RS01390 4e2eb84ab32baafaa1bb4dbfb2256605 344 SUPERFAMILY SSF56349 17 326 3.83E-44 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 BWK49_RS01390 4e2eb84ab32baafaa1bb4dbfb2256605 344 Pfam PF00589 Phage integrase family 151 318 7.8E-25 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 BWK49_RS01390 4e2eb84ab32baafaa1bb4dbfb2256605 344 Gene3D G3DSA:1.10.443.10 132 326 4.9E-37 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 BWK49_RS01390 4e2eb84ab32baafaa1bb4dbfb2256605 344 Gene3D G3DSA:1.10.150.130 17 111 4.3E-9 T 06-07-2017 IPR023109 Integrase/recombinase, N-terminal BWK49_RS05205 52b0641d19ba374f3c64b30c19bfe1dd 222 SUPERFAMILY SSF46689 15 85 2.26E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS05205 52b0641d19ba374f3c64b30c19bfe1dd 222 Gene3D G3DSA:1.10.357.10 12 198 7.6E-23 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS05205 52b0641d19ba374f3c64b30c19bfe1dd 222 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 70 2.5E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS02790 2e43bdadc38eee84f6886bb2216ae7fc 265 Gene3D G3DSA:1.10.1670.10 154 237 5.5E-31 T 06-07-2017 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 BWK49_RS02790 2e43bdadc38eee84f6886bb2216ae7fc 265 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 65 199 1.4E-21 T 06-07-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 BWK49_RS02790 2e43bdadc38eee84f6886bb2216ae7fc 265 TIGRFAM TIGR01083 nth: endonuclease III 36 225 1.0E-77 T 06-07-2017 IPR005759 Endonuclease III GO:0003906|GO:0006284 BWK49_RS02790 2e43bdadc38eee84f6886bb2216ae7fc 265 ProSitePatterns PS01155 Endonuclease III family signature. 133 162 - T 06-07-2017 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 BWK49_RS02790 2e43bdadc38eee84f6886bb2216ae7fc 265 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 218 234 - T 06-07-2017 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 BWK49_RS02790 2e43bdadc38eee84f6886bb2216ae7fc 265 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 218 234 6.7E-4 T 06-07-2017 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 BWK49_RS02790 2e43bdadc38eee84f6886bb2216ae7fc 265 Gene3D G3DSA:1.10.340.30 53 153 3.2E-34 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 BWK49_RS02790 2e43bdadc38eee84f6886bb2216ae7fc 265 Pfam PF00633 Helix-hairpin-helix motif 130 157 2.1E-9 T 06-07-2017 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 BWK49_RS02790 2e43bdadc38eee84f6886bb2216ae7fc 265 SMART SM00478 69 216 3.5E-59 T 06-07-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 BWK49_RS02790 2e43bdadc38eee84f6886bb2216ae7fc 265 Hamap MF_00942 Endonuclease III [nth]. 27 240 36.697 T 06-07-2017 IPR005759 Endonuclease III GO:0003906|GO:0006284 BWK49_RS02790 2e43bdadc38eee84f6886bb2216ae7fc 265 SMART SM00525 217 237 2.9E-5 T 06-07-2017 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 BWK49_RS02790 2e43bdadc38eee84f6886bb2216ae7fc 265 SUPERFAMILY SSF48150 38 236 7.22E-64 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 BWK49_RS22985 7a3e1df62ab4f4c2ecb793fd3706adaa 465 Gene3D G3DSA:3.30.310.50 375 456 4.2E-20 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 BWK49_RS22985 7a3e1df62ab4f4c2ecb793fd3706adaa 465 SUPERFAMILY SSF53738 265 369 1.73E-29 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 BWK49_RS22985 7a3e1df62ab4f4c2ecb793fd3706adaa 465 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 239 254 1.7E-21 T 06-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 BWK49_RS22985 7a3e1df62ab4f4c2ecb793fd3706adaa 465 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 98 112 1.7E-21 T 06-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 BWK49_RS22985 7a3e1df62ab4f4c2ecb793fd3706adaa 465 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 210 223 1.7E-21 T 06-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 BWK49_RS22985 7a3e1df62ab4f4c2ecb793fd3706adaa 465 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 175 194 1.7E-21 T 06-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 BWK49_RS22985 7a3e1df62ab4f4c2ecb793fd3706adaa 465 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 271 373 4.1E-24 T 06-07-2017 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 BWK49_RS22985 7a3e1df62ab4f4c2ecb793fd3706adaa 465 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 378 454 3.2E-12 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 BWK49_RS22985 7a3e1df62ab4f4c2ecb793fd3706adaa 465 SUPERFAMILY SSF53738 158 261 2.38E-27 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 BWK49_RS22985 7a3e1df62ab4f4c2ecb793fd3706adaa 465 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 159 259 1.4E-22 T 06-07-2017 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 BWK49_RS22985 7a3e1df62ab4f4c2ecb793fd3706adaa 465 Gene3D G3DSA:3.40.120.10 177 255 2.1E-28 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 BWK49_RS22985 7a3e1df62ab4f4c2ecb793fd3706adaa 465 SUPERFAMILY SSF53738 10 127 3.1E-32 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 BWK49_RS22985 7a3e1df62ab4f4c2ecb793fd3706adaa 465 SUPERFAMILY SSF55957 374 456 2.62E-19 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 BWK49_RS22985 7a3e1df62ab4f4c2ecb793fd3706adaa 465 Gene3D G3DSA:3.40.120.10 256 373 5.5E-36 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 BWK49_RS22985 7a3e1df62ab4f4c2ecb793fd3706adaa 465 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 12 125 8.0E-31 T 06-07-2017 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 BWK49_RS22985 7a3e1df62ab4f4c2ecb793fd3706adaa 465 Gene3D G3DSA:3.40.120.10 13 127 9.6E-30 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 BWK49_RS14580 5a54ed9ee1ca62d6d9e4d0d25f6b577d 148 Gene3D G3DSA:3.30.530.20 7 143 1.1E-12 T 06-07-2017 IPR023393 START-like domain BWK49_RS14580 5a54ed9ee1ca62d6d9e4d0d25f6b577d 148 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 6 140 4.2E-14 T 06-07-2017 IPR019587 Polyketide cyclase/dehydrase BWK49_RS14580 5a54ed9ee1ca62d6d9e4d0d25f6b577d 148 SUPERFAMILY SSF55961 1 142 1.9E-26 T 06-07-2017 BWK49_RS15120 a6e563f444dff80a9a57d4ce82b1d833 777 Gene3D G3DSA:3.40.50.300 406 563 1.7E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS15120 a6e563f444dff80a9a57d4ce82b1d833 777 Pfam PF07517 SecA DEAD-like domain 18 389 3.8E-83 T 06-07-2017 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 BWK49_RS15120 a6e563f444dff80a9a57d4ce82b1d833 777 ProSitePatterns PS01312 SecA family signature. 489 504 - T 06-07-2017 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 BWK49_RS15120 a6e563f444dff80a9a57d4ce82b1d833 777 TIGRFAM TIGR04221 SecA2_Mycobac: accessory Sec system translocase SecA2 13 777 0.0 T 06-07-2017 IPR026389 Protein translocase subunit SecA, Actinobacteria-type BWK49_RS15120 a6e563f444dff80a9a57d4ce82b1d833 777 SUPERFAMILY SSF81886 590 740 4.32E-31 T 06-07-2017 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 BWK49_RS15120 a6e563f444dff80a9a57d4ce82b1d833 777 PRINTS PR00906 SecA protein signature 124 134 1.4E-42 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 BWK49_RS15120 a6e563f444dff80a9a57d4ce82b1d833 777 PRINTS PR00906 SecA protein signature 402 415 1.4E-42 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 BWK49_RS15120 a6e563f444dff80a9a57d4ce82b1d833 777 PRINTS PR00906 SecA protein signature 108 122 1.4E-42 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 BWK49_RS15120 a6e563f444dff80a9a57d4ce82b1d833 777 PRINTS PR00906 SecA protein signature 328 350 1.4E-42 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 BWK49_RS15120 a6e563f444dff80a9a57d4ce82b1d833 777 PRINTS PR00906 SecA protein signature 70 94 1.4E-42 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 BWK49_RS15120 a6e563f444dff80a9a57d4ce82b1d833 777 PRINTS PR00906 SecA protein signature 177 197 1.4E-42 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 BWK49_RS15120 a6e563f444dff80a9a57d4ce82b1d833 777 PRINTS PR00906 SecA protein signature 365 382 1.4E-42 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 BWK49_RS15120 a6e563f444dff80a9a57d4ce82b1d833 777 SMART SM00958 234 347 2.7E-25 T 06-07-2017 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 BWK49_RS15120 a6e563f444dff80a9a57d4ce82b1d833 777 SUPERFAMILY SSF81767 244 355 9.81E-30 T 06-07-2017 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 BWK49_RS15120 a6e563f444dff80a9a57d4ce82b1d833 777 SUPERFAMILY SSF52540 357 404 2.83E-49 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS15120 a6e563f444dff80a9a57d4ce82b1d833 777 SUPERFAMILY SSF52540 16 235 2.83E-49 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS15120 a6e563f444dff80a9a57d4ce82b1d833 777 SUPERFAMILY SSF52540 406 564 1.83E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS15120 a6e563f444dff80a9a57d4ce82b1d833 777 Hamap MF_01382 Protein translocase subunit SecA [secA]. 15 735 15.353 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 BWK49_RS15120 a6e563f444dff80a9a57d4ce82b1d833 777 Gene3D G3DSA:1.10.3060.10 608 728 5.4E-27 T 06-07-2017 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 BWK49_RS15120 a6e563f444dff80a9a57d4ce82b1d833 777 Pfam PF01043 SecA preprotein cross-linking domain 247 347 2.7E-21 T 06-07-2017 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 BWK49_RS15120 a6e563f444dff80a9a57d4ce82b1d833 777 SMART SM00957 16 391 1.1E-143 T 06-07-2017 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 BWK49_RS15120 a6e563f444dff80a9a57d4ce82b1d833 777 Pfam PF07516 SecA Wing and Scaffold domain 638 721 1.3E-14 T 06-07-2017 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 BWK49_RS15120 a6e563f444dff80a9a57d4ce82b1d833 777 Gene3D G3DSA:3.40.50.300 8 235 3.7E-77 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS15120 a6e563f444dff80a9a57d4ce82b1d833 777 Gene3D G3DSA:3.40.50.300 358 405 3.7E-77 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS15120 a6e563f444dff80a9a57d4ce82b1d833 777 Gene3D G3DSA:3.90.1440.10 244 355 2.8E-31 T 06-07-2017 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 BWK49_RS16085 8848d5402891d0d12fdc60696482920e 149 Gene3D G3DSA:1.20.1510.10 27 136 4.5E-6 T 06-07-2017 IPR027469 Cation efflux protein transmembrane domain BWK49_RS16085 8848d5402891d0d12fdc60696482920e 149 SUPERFAMILY SSF161111 20 143 2.22E-14 T 06-07-2017 BWK49_RS16085 8848d5402891d0d12fdc60696482920e 149 Pfam PF01545 Cation efflux family 28 139 6.0E-8 T 06-07-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 BWK49_RS25120 69ca34b5be1c2876186dcfa375f22e7d 335 Gene3D G3DSA:3.40.47.10 171 331 2.1E-42 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS25120 69ca34b5be1c2876186dcfa375f22e7d 335 SUPERFAMILY SSF53901 5 332 1.69E-63 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS25120 69ca34b5be1c2876186dcfa375f22e7d 335 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 116 193 7.1E-25 T 06-07-2017 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 BWK49_RS25120 69ca34b5be1c2876186dcfa375f22e7d 335 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 11 332 61.221 T 06-07-2017 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 BWK49_RS25120 69ca34b5be1c2876186dcfa375f22e7d 335 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 13 331 1.0E-125 T 06-07-2017 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 BWK49_RS25120 69ca34b5be1c2876186dcfa375f22e7d 335 Gene3D G3DSA:3.40.47.10 12 170 2.2E-57 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS25120 69ca34b5be1c2876186dcfa375f22e7d 335 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 242 331 4.8E-30 T 06-07-2017 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 BWK49_RS18440 8ca8a4ee68dc4513a4710befab9319d9 420 Pfam PF02441 Flavoprotein 8 134 1.2E-27 T 06-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 BWK49_RS18440 8ca8a4ee68dc4513a4710befab9319d9 420 Gene3D G3DSA:3.40.50.1950 7 183 3.0E-57 T 06-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 BWK49_RS18440 8ca8a4ee68dc4513a4710befab9319d9 420 SUPERFAMILY SSF102645 181 415 3.14E-61 T 06-07-2017 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 BWK49_RS18440 8ca8a4ee68dc4513a4710befab9319d9 420 SUPERFAMILY SSF52507 8 175 1.13E-54 T 06-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 BWK49_RS18440 8ca8a4ee68dc4513a4710befab9319d9 420 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 190 386 7.2E-64 T 06-07-2017 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 BWK49_RS18440 8ca8a4ee68dc4513a4710befab9319d9 420 Gene3D G3DSA:3.40.50.10300 187 416 4.3E-75 T 06-07-2017 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 BWK49_RS18440 8ca8a4ee68dc4513a4710befab9319d9 420 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 8 411 9.1E-110 T 06-07-2017 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5 BWK49_RS18330 c6117a5c1edbe08a8ad52772fc1dfef3 489 Pfam PF00823 PPE family 8 164 1.4E-54 T 06-07-2017 IPR000030 PPE family BWK49_RS18330 c6117a5c1edbe08a8ad52772fc1dfef3 489 SUPERFAMILY SSF140459 5 177 8.89E-57 T 06-07-2017 BWK49_RS09855 753531a127173974d6064edab209365e 215 Pfam PF14279 HNH endonuclease 131 177 1.0E-13 T 06-07-2017 IPR029471 HNH endonuclease 5 BWK49_RS09855 753531a127173974d6064edab209365e 215 SMART SM00507 118 167 1.5E-15 T 06-07-2017 IPR003615 HNH nuclease BWK49_RS12990 93269cd1c5d2204e7463dfe4e2feadbf 405 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 129 141 - T 06-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 BWK49_RS12990 93269cd1c5d2204e7463dfe4e2feadbf 405 SUPERFAMILY SSF56112 7 268 9.44E-72 T 06-07-2017 IPR011009 Protein kinase-like domain BWK49_RS12990 93269cd1c5d2204e7463dfe4e2feadbf 405 Gene3D G3DSA:3.30.200.20 5 89 5.2E-22 T 06-07-2017 BWK49_RS12990 93269cd1c5d2204e7463dfe4e2feadbf 405 Gene3D G3DSA:1.10.510.10 92 330 2.6E-46 T 06-07-2017 BWK49_RS12990 93269cd1c5d2204e7463dfe4e2feadbf 405 SMART SM00220 10 274 1.1E-58 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 BWK49_RS12990 93269cd1c5d2204e7463dfe4e2feadbf 405 Pfam PF00069 Protein kinase domain 13 256 3.9E-47 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 BWK49_RS06595 98204f18ac231e56670379cd8b6bfea0 364 Pfam PF04055 Radical SAM superfamily 48 209 1.1E-25 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 BWK49_RS06595 98204f18ac231e56670379cd8b6bfea0 364 SMART SM00729 43 248 1.3E-10 T 06-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 BWK49_RS06595 98204f18ac231e56670379cd8b6bfea0 364 Pfam PF06463 Molybdenum Cofactor Synthesis C 215 346 1.5E-36 T 06-07-2017 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|Reactome: R-HSA-947581 BWK49_RS06595 98204f18ac231e56670379cd8b6bfea0 364 SUPERFAMILY SSF102114 33 312 2.75E-67 T 06-07-2017 BWK49_RS06595 98204f18ac231e56670379cd8b6bfea0 364 Hamap MF_01225_B Cyclic pyranopterin monophosphate synthase [moaA]. 34 364 39.394 T 06-07-2017 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|Reactome: R-HSA-947581 BWK49_RS06595 98204f18ac231e56670379cd8b6bfea0 364 Gene3D G3DSA:3.20.20.70 33 341 1.1E-69 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 BWK49_RS06595 98204f18ac231e56670379cd8b6bfea0 364 Pfam PF13353 4Fe-4S single cluster domain 50 125 2.7E-5 T 06-07-2017 BWK49_RS06595 98204f18ac231e56670379cd8b6bfea0 364 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 34 364 5.4E-109 T 06-07-2017 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|Reactome: R-HSA-947581 BWK49_RS06595 98204f18ac231e56670379cd8b6bfea0 364 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 49 60 - T 06-07-2017 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|Reactome: R-HSA-947581 BWK49_RS05760 41acb137f878270dcdc0163901b4c4b6 298 Gene3D G3DSA:3.40.50.150 78 215 1.3E-16 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS05760 41acb137f878270dcdc0163901b4c4b6 298 Pfam PF04072 Leucine carboxyl methyltransferase 18 200 7.6E-40 T 06-07-2017 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 BWK49_RS05760 41acb137f878270dcdc0163901b4c4b6 298 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 15 276 1.5E-52 T 06-07-2017 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 BWK49_RS05760 41acb137f878270dcdc0163901b4c4b6 298 SUPERFAMILY SSF53335 14 280 1.29E-56 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS24185 7b941c9383a21dee43d01695591260ed 254 SUPERFAMILY SSF51735 4 225 2.49E-63 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS24185 7b941c9383a21dee43d01695591260ed 254 Pfam PF00106 short chain dehydrogenase 5 191 2.4E-52 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS24185 7b941c9383a21dee43d01695591260ed 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 1.6E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS24185 7b941c9383a21dee43d01695591260ed 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 1.6E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS24185 7b941c9383a21dee43d01695591260ed 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 1.6E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS24185 7b941c9383a21dee43d01695591260ed 254 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4 193 8.5E-6 T 06-07-2017 BWK49_RS24185 7b941c9383a21dee43d01695591260ed 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 2.6E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS24185 7b941c9383a21dee43d01695591260ed 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 2.6E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS24185 7b941c9383a21dee43d01695591260ed 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 2.6E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS24185 7b941c9383a21dee43d01695591260ed 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 2.6E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS24185 7b941c9383a21dee43d01695591260ed 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 2.6E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS24185 7b941c9383a21dee43d01695591260ed 254 Gene3D G3DSA:3.40.50.720 5 222 5.5E-63 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS24185 7b941c9383a21dee43d01695591260ed 254 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS26865 793873d95d38e1a57773c0bc0e91b212 472 Pfam PF00171 Aldehyde dehydrogenase family 3 455 1.4E-140 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 BWK49_RS26865 793873d95d38e1a57773c0bc0e91b212 472 Gene3D G3DSA:3.40.605.10 3 245 4.0E-74 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 BWK49_RS26865 793873d95d38e1a57773c0bc0e91b212 472 SUPERFAMILY SSF53720 3 458 1.26E-146 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 BWK49_RS26865 793873d95d38e1a57773c0bc0e91b212 472 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 259 270 - T 06-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 BWK49_RS26865 793873d95d38e1a57773c0bc0e91b212 472 Gene3D G3DSA:3.40.309.10 246 430 5.2E-67 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 BWK49_RS13460 6c5a7770fe4fb244e2d39b483fc1af74 318 SUPERFAMILY SSF88723 2 185 9.48E-39 T 06-07-2017 IPR029060 PIN domain-like BWK49_RS13460 6c5a7770fe4fb244e2d39b483fc1af74 318 SMART SM00279 192 227 6.9E-10 T 06-07-2017 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 BWK49_RS13460 6c5a7770fe4fb244e2d39b483fc1af74 318 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 195 279 4.5E-18 T 06-07-2017 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 BWK49_RS13460 6c5a7770fe4fb244e2d39b483fc1af74 318 SMART SM00475 3 284 1.1E-105 T 06-07-2017 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 BWK49_RS13460 6c5a7770fe4fb244e2d39b483fc1af74 318 Gene3D G3DSA:1.10.150.20 185 251 7.2E-19 T 06-07-2017 BWK49_RS13460 6c5a7770fe4fb244e2d39b483fc1af74 318 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 5 185 7.8E-49 T 06-07-2017 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 BWK49_RS13460 6c5a7770fe4fb244e2d39b483fc1af74 318 Gene3D G3DSA:3.40.50.1010 3 184 3.5E-50 T 06-07-2017 IPR029060 PIN domain-like BWK49_RS13460 6c5a7770fe4fb244e2d39b483fc1af74 318 SUPERFAMILY SSF47807 195 310 6.28E-20 T 06-07-2017 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 BWK49_RS19590 f81f29f4c71690fb02804b7cb65f2aae 68 Pfam PF11248 Protein of unknown function (DUF3046) 5 66 1.3E-27 T 06-07-2017 IPR021408 Protein of unknown function DUF3046 BWK49_RS14910 ca95468722097bdb9dde408b504e1e6f 287 Gene3D G3DSA:3.40.50.720 18 247 7.0E-61 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS14910 ca95468722097bdb9dde408b504e1e6f 287 Pfam PF00106 short chain dehydrogenase 19 204 5.8E-47 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS14910 ca95468722097bdb9dde408b504e1e6f 287 SUPERFAMILY SSF51735 15 258 2.3E-62 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS14910 ca95468722097bdb9dde408b504e1e6f 287 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 90 101 2.2E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS14910 ca95468722097bdb9dde408b504e1e6f 287 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 163 182 2.2E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS14910 ca95468722097bdb9dde408b504e1e6f 287 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 143 151 2.2E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS14910 ca95468722097bdb9dde408b504e1e6f 287 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 150 178 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS14910 ca95468722097bdb9dde408b504e1e6f 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 20 37 2.1E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS14910 ca95468722097bdb9dde408b504e1e6f 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 90 101 2.1E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS14910 ca95468722097bdb9dde408b504e1e6f 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 184 201 2.1E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS14910 ca95468722097bdb9dde408b504e1e6f 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 137 153 2.1E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS14910 ca95468722097bdb9dde408b504e1e6f 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 182 2.1E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS14910 ca95468722097bdb9dde408b504e1e6f 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 2.1E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS26725 5b452f3b4684e4a34fb78b25db5e9e4c 214 SUPERFAMILY SSF46689 5 85 6.16E-20 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS26725 5b452f3b4684e4a34fb78b25db5e9e4c 214 SUPERFAMILY SSF48498 84 193 5.78E-9 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS26725 5b452f3b4684e4a34fb78b25db5e9e4c 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 2.7E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS26725 5b452f3b4684e4a34fb78b25db5e9e4c 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 2.7E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS26725 5b452f3b4684e4a34fb78b25db5e9e4c 214 Gene3D G3DSA:1.10.357.10 4 198 1.7E-44 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS26725 5b452f3b4684e4a34fb78b25db5e9e4c 214 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 63 1.0E-16 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS06605 79537231eb152ca6da3da09739a83cb0 135 SMART SM00357 3 65 3.8E-23 T 06-07-2017 IPR011129 Cold shock protein GO:0003676 BWK49_RS06605 79537231eb152ca6da3da09739a83cb0 135 PRINTS PR00050 Cold shock protein signature 4 19 6.2E-12 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 BWK49_RS06605 79537231eb152ca6da3da09739a83cb0 135 PRINTS PR00050 Cold shock protein signature 24 33 6.2E-12 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 BWK49_RS06605 79537231eb152ca6da3da09739a83cb0 135 PRINTS PR00050 Cold shock protein signature 38 56 6.2E-12 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 BWK49_RS06605 79537231eb152ca6da3da09739a83cb0 135 SUPERFAMILY SSF50249 2 68 4.71E-16 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS06605 79537231eb152ca6da3da09739a83cb0 135 Pfam PF00313 'Cold-shock' DNA-binding domain 3 62 5.2E-16 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 BWK49_RS06605 79537231eb152ca6da3da09739a83cb0 135 Gene3D G3DSA:2.40.50.140 2 67 1.3E-21 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS24035 8e0e4738b36bbcb4f053674d8313771f 508 SUPERFAMILY SSF51206 14 136 1.96E-17 T 06-07-2017 IPR018490 Cyclic nucleotide-binding-like BWK49_RS24035 8e0e4738b36bbcb4f053674d8313771f 508 Gene3D G3DSA:3.30.565.10 332 488 9.7E-36 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS24035 8e0e4738b36bbcb4f053674d8313771f 508 SUPERFAMILY SSF55874 321 488 2.23E-33 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS24035 8e0e4738b36bbcb4f053674d8313771f 508 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 381 487 4.0E-17 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS24035 8e0e4738b36bbcb4f053674d8313771f 508 PRINTS PR00344 Bacterial sensor protein C-terminal signature 472 485 9.6E-10 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 BWK49_RS24035 8e0e4738b36bbcb4f053674d8313771f 508 PRINTS PR00344 Bacterial sensor protein C-terminal signature 435 445 9.6E-10 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 BWK49_RS24035 8e0e4738b36bbcb4f053674d8313771f 508 PRINTS PR00344 Bacterial sensor protein C-terminal signature 417 431 9.6E-10 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 BWK49_RS24035 8e0e4738b36bbcb4f053674d8313771f 508 PRINTS PR00344 Bacterial sensor protein C-terminal signature 448 466 9.6E-10 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 BWK49_RS24035 8e0e4738b36bbcb4f053674d8313771f 508 Pfam PF00027 Cyclic nucleotide-binding domain 47 128 5.5E-7 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain BWK49_RS24035 8e0e4738b36bbcb4f053674d8313771f 508 SMART SM00387 378 488 7.3E-26 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS24035 8e0e4738b36bbcb4f053674d8313771f 508 Gene3D G3DSA:2.60.120.10 16 135 9.7E-14 T 06-07-2017 IPR014710 RmlC-like jelly roll fold BWK49_RS19845 ce00ac9e5ae4d08e3c4f172e6c10f33b 410 Gene3D G3DSA:1.20.140.10 242 409 9.3E-50 T 06-07-2017 BWK49_RS19845 ce00ac9e5ae4d08e3c4f172e6c10f33b 410 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 141 241 7.9E-22 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 BWK49_RS19845 ce00ac9e5ae4d08e3c4f172e6c10f33b 410 SUPERFAMILY SSF47203 258 408 8.22E-40 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS19845 ce00ac9e5ae4d08e3c4f172e6c10f33b 410 SUPERFAMILY SSF56645 4 252 3.53E-52 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS19845 ce00ac9e5ae4d08e3c4f172e6c10f33b 410 Gene3D G3DSA:2.40.110.10 140 241 2.6E-31 T 06-07-2017 BWK49_RS19845 ce00ac9e5ae4d08e3c4f172e6c10f33b 410 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 258 407 2.0E-42 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS19845 ce00ac9e5ae4d08e3c4f172e6c10f33b 410 Gene3D G3DSA:1.10.540.10 3 139 7.6E-31 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS19845 ce00ac9e5ae4d08e3c4f172e6c10f33b 410 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 143 155 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 BWK49_RS19845 ce00ac9e5ae4d08e3c4f172e6c10f33b 410 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 135 7.4E-13 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS16675 3c499d8ce3c76af963c70f0e85544c88 335 Pfam PF13242 HAD-hyrolase-like 184 256 2.3E-15 T 06-07-2017 BWK49_RS16675 3c499d8ce3c76af963c70f0e85544c88 335 SUPERFAMILY SSF56784 8 257 2.96E-50 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS16675 3c499d8ce3c76af963c70f0e85544c88 335 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 12 231 2.7E-31 T 06-07-2017 IPR006357 HAD-superfamily hydrolase, subfamily IIA BWK49_RS16675 3c499d8ce3c76af963c70f0e85544c88 335 Gene3D G3DSA:3.40.50.1000 183 257 1.7E-31 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS16675 3c499d8ce3c76af963c70f0e85544c88 335 Gene3D G3DSA:3.40.50.1000 4 77 1.7E-31 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS16675 3c499d8ce3c76af963c70f0e85544c88 335 Pfam PF13344 Haloacid dehalogenase-like hydrolase 11 108 8.6E-20 T 06-07-2017 IPR006357 HAD-superfamily hydrolase, subfamily IIA BWK49_RS16675 3c499d8ce3c76af963c70f0e85544c88 335 Gene3D G3DSA:3.40.50.10410 78 182 2.2E-30 T 06-07-2017 IPR023215 Nitrophenylphosphatase-like domain BWK49_RS21760 5e1926c73e76fd9bcd4fc9a3beca4448 316 Gene3D G3DSA:3.40.190.10 193 257 2.3E-4 T 06-07-2017 BWK49_RS21760 5e1926c73e76fd9bcd4fc9a3beca4448 316 Gene3D G3DSA:1.10.10.10 7 85 3.0E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS21760 5e1926c73e76fd9bcd4fc9a3beca4448 316 Gene3D G3DSA:3.40.190.10 98 192 8.7E-12 T 06-07-2017 BWK49_RS21760 5e1926c73e76fd9bcd4fc9a3beca4448 316 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 68 6.8E-14 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 BWK49_RS21760 5e1926c73e76fd9bcd4fc9a3beca4448 316 Pfam PF03466 LysR substrate binding domain 94 293 2.9E-32 T 06-07-2017 IPR005119 LysR, substrate-binding BWK49_RS21760 5e1926c73e76fd9bcd4fc9a3beca4448 316 SUPERFAMILY SSF53850 94 301 4.89E-32 T 06-07-2017 BWK49_RS21760 5e1926c73e76fd9bcd4fc9a3beca4448 316 SUPERFAMILY SSF46785 8 89 1.72E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS10585 d957b0cee5cbbff2a6542d6d75f28250 311 Pfam PF00146 NADH dehydrogenase 45 303 3.0E-44 T 06-07-2017 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS10240 2f43a5dad2bf91d682db6a014c320fc1 272 SUPERFAMILY SSF161098 8 259 2.09E-49 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS10240 2f43a5dad2bf91d682db6a014c320fc1 272 TIGRFAM TIGR00969 3a0106s02: sulfate ABC transporter, permease protein 9 264 6.9E-105 T 06-07-2017 IPR005667 Sulphate ABC transporter permease protein 2 GO:0008272|GO:0015419|GO:0016020 BWK49_RS10240 2f43a5dad2bf91d682db6a014c320fc1 272 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 73 264 1.3E-17 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS10240 2f43a5dad2bf91d682db6a014c320fc1 272 Gene3D G3DSA:1.10.3720.10 11 265 4.5E-47 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS10240 2f43a5dad2bf91d682db6a014c320fc1 272 TIGRFAM TIGR02140 permease_CysW: sulfate ABC transporter, permease protein CysW 7 266 8.0E-112 T 06-07-2017 IPR011866 Sulphate ABC transporter, permease protein CysW GO:0008272|GO:0015116|GO:0016021 BWK49_RS09300 e867bfeeb59f6d85ae76408cbba93758 541 ProSitePatterns PS00455 Putative AMP-binding domain signature. 179 190 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS09300 e867bfeeb59f6d85ae76408cbba93758 541 Gene3D G3DSA:3.30.300.30 436 529 8.0E-26 T 06-07-2017 BWK49_RS09300 e867bfeeb59f6d85ae76408cbba93758 541 Gene3D G3DSA:3.40.50.980 185 342 5.7E-26 T 06-07-2017 BWK49_RS09300 e867bfeeb59f6d85ae76408cbba93758 541 Gene3D G3DSA:2.30.38.10 382 432 4.6E-6 T 06-07-2017 BWK49_RS09300 e867bfeeb59f6d85ae76408cbba93758 541 Pfam PF00501 AMP-binding enzyme 16 437 2.5E-45 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS09300 e867bfeeb59f6d85ae76408cbba93758 541 Gene3D G3DSA:3.40.50.980 5 184 3.9E-23 T 06-07-2017 BWK49_RS09300 e867bfeeb59f6d85ae76408cbba93758 541 SUPERFAMILY SSF56801 4 533 2.62E-91 T 06-07-2017 BWK49_RS09300 e867bfeeb59f6d85ae76408cbba93758 541 Pfam PF13193 AMP-binding enzyme C-terminal domain 448 523 1.1E-15 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS28960 3c383bca7e17b33afa88ef9c77be2f57 316 SUPERFAMILY SSF54001 200 305 1.5E-29 T 06-07-2017 BWK49_RS28960 3c383bca7e17b33afa88ef9c77be2f57 316 Gene3D G3DSA:3.90.1720.10 199 305 2.7E-32 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain BWK49_RS28960 3c383bca7e17b33afa88ef9c77be2f57 316 Pfam PF00877 NlpC/P60 family 213 302 3.9E-19 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain BWK49_RS16430 633452b156b828f1a143a2c7157948fb 432 SMART SM00825 Beta-ketoacyl synthase 7 429 6.5E-122 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain BWK49_RS16430 633452b156b828f1a143a2c7157948fb 432 SUPERFAMILY SSF53901 2 372 2.09E-83 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS16430 633452b156b828f1a143a2c7157948fb 432 SUPERFAMILY SSF53901 404 425 2.09E-83 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS16430 633452b156b828f1a143a2c7157948fb 432 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 262 374 7.1E-30 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal BWK49_RS16430 633452b156b828f1a143a2c7157948fb 432 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 167 183 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site BWK49_RS16430 633452b156b828f1a143a2c7157948fb 432 Gene3D G3DSA:3.40.47.10 270 426 1.2E-45 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS16430 633452b156b828f1a143a2c7157948fb 432 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 5 254 1.1E-70 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal BWK49_RS16430 633452b156b828f1a143a2c7157948fb 432 Gene3D G3DSA:3.40.47.10 7 266 3.5E-75 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS27875 62ce039ae29a8c7f35e4a9913e90662c 301 Gene3D G3DSA:3.40.50.720 37 257 6.4E-59 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS27875 62ce039ae29a8c7f35e4a9913e90662c 301 SUPERFAMILY SSF51735 37 268 1.09E-58 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS27875 62ce039ae29a8c7f35e4a9913e90662c 301 Pfam PF00106 short chain dehydrogenase 39 229 6.4E-46 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27875 62ce039ae29a8c7f35e4a9913e90662c 301 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 114 125 1.2E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27875 62ce039ae29a8c7f35e4a9913e90662c 301 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 169 177 1.2E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27875 62ce039ae29a8c7f35e4a9913e90662c 301 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 190 209 1.2E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27875 62ce039ae29a8c7f35e4a9913e90662c 301 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 114 125 6.9E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27875 62ce039ae29a8c7f35e4a9913e90662c 301 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 179 6.9E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27875 62ce039ae29a8c7f35e4a9913e90662c 301 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 40 57 6.9E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27875 62ce039ae29a8c7f35e4a9913e90662c 301 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 190 209 6.9E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS22545 3ee001b5a4ef1d966f3c677bbf17b82d 237 SUPERFAMILY SSF55469 1 63 1.44E-38 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 BWK49_RS22545 3ee001b5a4ef1d966f3c677bbf17b82d 237 SUPERFAMILY SSF55469 104 206 1.44E-38 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 BWK49_RS22545 3ee001b5a4ef1d966f3c677bbf17b82d 237 Gene3D G3DSA:3.40.109.10 104 207 3.4E-35 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 BWK49_RS22545 3ee001b5a4ef1d966f3c677bbf17b82d 237 Gene3D G3DSA:3.40.109.10 1 63 3.4E-35 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 BWK49_RS22545 3ee001b5a4ef1d966f3c677bbf17b82d 237 Pfam PF00881 Nitroreductase family 10 182 8.3E-22 T 06-07-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 BWK49_RS02145 2227f43bbc34ce0c89e0a67c75c5c244 220 SUPERFAMILY SSF53335 8 182 9.88E-32 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS02145 2227f43bbc34ce0c89e0a67c75c5c244 220 Gene3D G3DSA:3.40.50.150 19 183 2.8E-34 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS02145 2227f43bbc34ce0c89e0a67c75c5c244 220 Pfam PF13649 Methyltransferase domain 42 136 5.8E-16 T 06-07-2017 BWK49_RS14230 87b2c6bb69bbd6a96c1413f3c77fcd03 499 Gene3D G3DSA:3.40.50.720 27 204 1.9E-51 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS14230 87b2c6bb69bbd6a96c1413f3c77fcd03 499 PIRSF PIRSF000110 13 489 2.5E-135 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 BWK49_RS14230 87b2c6bb69bbd6a96c1413f3c77fcd03 499 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 332 358 1.1E-36 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 BWK49_RS14230 87b2c6bb69bbd6a96c1413f3c77fcd03 499 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 255 271 1.1E-36 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 BWK49_RS14230 87b2c6bb69bbd6a96c1413f3c77fcd03 499 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 161 174 1.1E-36 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 BWK49_RS14230 87b2c6bb69bbd6a96c1413f3c77fcd03 499 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 185 213 1.1E-36 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 BWK49_RS14230 87b2c6bb69bbd6a96c1413f3c77fcd03 499 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 237 254 1.1E-36 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 BWK49_RS14230 87b2c6bb69bbd6a96c1413f3c77fcd03 499 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 28 496 77.149 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 BWK49_RS14230 87b2c6bb69bbd6a96c1413f3c77fcd03 499 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 207 485 3.7E-85 T 06-07-2017 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 BWK49_RS14230 87b2c6bb69bbd6a96c1413f3c77fcd03 499 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 28 484 3.4E-130 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 BWK49_RS14230 87b2c6bb69bbd6a96c1413f3c77fcd03 499 SUPERFAMILY SSF51735 20 208 4.72E-47 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS14230 87b2c6bb69bbd6a96c1413f3c77fcd03 499 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 32 205 4.1E-45 T 06-07-2017 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 BWK49_RS14230 87b2c6bb69bbd6a96c1413f3c77fcd03 499 ProSitePatterns PS00069 Glucose-6-phosphate dehydrogenase active site. 195 201 - T 06-07-2017 IPR019796 Glucose-6-phosphate dehydrogenase, active site GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 BWK49_RS14230 87b2c6bb69bbd6a96c1413f3c77fcd03 499 SUPERFAMILY SSF55347 195 493 3.27E-90 T 06-07-2017 BWK49_RS14230 87b2c6bb69bbd6a96c1413f3c77fcd03 499 Gene3D G3DSA:3.30.360.10 205 485 9.4E-91 T 06-07-2017 BWK49_RS20050 e9a53a10215790d9a842f28fd0783b92 506 Gene3D G3DSA:3.40.50.880 259 443 5.9E-37 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like BWK49_RS20050 e9a53a10215790d9a842f28fd0783b92 506 SUPERFAMILY SSF52540 4 242 1.31E-51 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS20050 e9a53a10215790d9a842f28fd0783b92 506 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 259 437 3.1E-43 T 06-07-2017 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 BWK49_RS20050 e9a53a10215790d9a842f28fd0783b92 506 SUPERFAMILY SSF52317 258 429 4.45E-36 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like BWK49_RS20050 e9a53a10215790d9a842f28fd0783b92 506 Gene3D G3DSA:3.40.50.300 4 239 5.2E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS20050 e9a53a10215790d9a842f28fd0783b92 506 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 6 232 2.0E-26 T 06-07-2017 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain BWK49_RS20050 e9a53a10215790d9a842f28fd0783b92 506 TIGRFAM TIGR00313 cobQ: cobyric acid synthase CobQ 5 484 5.7E-135 T 06-07-2017 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 BWK49_RS20050 e9a53a10215790d9a842f28fd0783b92 506 Hamap MF_00028 Cobyric acid synthase [cobQ]. 1 493 175.445 T 06-07-2017 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 BWK49_RS01565 d1417feaa4975adbdb8c8488a65bb10f 469 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 82 102 2.5E-47 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS01565 d1417feaa4975adbdb8c8488a65bb10f 469 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 154 180 2.5E-47 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS01565 d1417feaa4975adbdb8c8488a65bb10f 469 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 103 123 2.5E-47 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS01565 d1417feaa4975adbdb8c8488a65bb10f 469 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 31 56 2.5E-47 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS01565 d1417feaa4975adbdb8c8488a65bb10f 469 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 198 220 2.5E-47 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS01565 d1417feaa4975adbdb8c8488a65bb10f 469 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 61 76 2.5E-47 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS01565 d1417feaa4975adbdb8c8488a65bb10f 469 Gene3D G3DSA:3.90.380.10 142 455 9.4E-88 T 06-07-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 BWK49_RS01565 d1417feaa4975adbdb8c8488a65bb10f 469 SUPERFAMILY SSF50022 16 170 6.29E-40 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS01565 d1417feaa4975adbdb8c8488a65bb10f 469 ProSitePatterns PS00570 Bacterial ring hydroxylating dioxygenases alpha-subunit signature. 89 112 - T 06-07-2017 IPR015881 Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site GO:0005506|GO:0016705|GO:0051537|GO:0055114 BWK49_RS01565 d1417feaa4975adbdb8c8488a65bb10f 469 SUPERFAMILY SSF55961 170 457 1.33E-50 T 06-07-2017 BWK49_RS01565 d1417feaa4975adbdb8c8488a65bb10f 469 Gene3D G3DSA:2.102.10.10 34 126 4.1E-17 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS01565 d1417feaa4975adbdb8c8488a65bb10f 469 Pfam PF00355 Rieske [2Fe-2S] domain 47 127 4.7E-17 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS01565 d1417feaa4975adbdb8c8488a65bb10f 469 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 208 449 1.6E-18 T 06-07-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 BWK49_RS26860 6ac1fb204ff97ddf1cae01f15bb2ed4c 549 SUPERFAMILY SSF52518 359 538 2.95E-53 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS26860 6ac1fb204ff97ddf1cae01f15bb2ed4c 549 Gene3D G3DSA:3.40.50.1220 183 333 1.9E-46 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain BWK49_RS26860 6ac1fb204ff97ddf1cae01f15bb2ed4c 549 SUPERFAMILY SSF52518 3 177 3.93E-45 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS26860 6ac1fb204ff97ddf1cae01f15bb2ed4c 549 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 190 324 5.3E-38 T 06-07-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 BWK49_RS26860 6ac1fb204ff97ddf1cae01f15bb2ed4c 549 Gene3D G3DSA:3.40.50.970 356 543 3.9E-58 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS26860 6ac1fb204ff97ddf1cae01f15bb2ed4c 549 SUPERFAMILY SSF52467 184 333 7.06E-44 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain BWK49_RS26860 6ac1fb204ff97ddf1cae01f15bb2ed4c 549 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 419 438 - T 06-07-2017 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 BWK49_RS26860 6ac1fb204ff97ddf1cae01f15bb2ed4c 549 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 382 527 3.6E-40 T 06-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 BWK49_RS26860 6ac1fb204ff97ddf1cae01f15bb2ed4c 549 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 4 164 4.2E-47 T 06-07-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 BWK49_RS26860 6ac1fb204ff97ddf1cae01f15bb2ed4c 549 Gene3D G3DSA:3.40.50.970 3 178 2.1E-56 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS01940 841832f79295fd438d0cebc182d0b3c7 224 Gene3D G3DSA:3.40.810.20 23 221 2.1E-70 T 06-07-2017 BWK49_RS01940 841832f79295fd438d0cebc182d0b3c7 224 TIGRFAM TIGR02428 pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit 21 217 5.2E-77 T 06-07-2017 IPR012791 3-oxoacid CoA-transferase, subunit B GO:0008410 BWK49_RS01940 841832f79295fd438d0cebc182d0b3c7 224 SUPERFAMILY SSF100950 23 209 5.15E-57 T 06-07-2017 BWK49_RS01940 841832f79295fd438d0cebc182d0b3c7 224 Pfam PF01144 Coenzyme A transferase 23 199 5.7E-32 T 06-07-2017 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 BWK49_RS01940 841832f79295fd438d0cebc182d0b3c7 224 SMART SM00882 22 219 1.1E-54 T 06-07-2017 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 BWK49_RS20935 4081b22105196b98f48406920998cc43 333 SUPERFAMILY SSF51735 1 180 1.7E-69 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS20935 4081b22105196b98f48406920998cc43 333 SUPERFAMILY SSF48179 181 326 3.23E-66 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 BWK49_RS20935 4081b22105196b98f48406920998cc43 333 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 12 175 3.7E-70 T 06-07-2017 IPR013116 Acetohydroxy acid isomeroreductase, NADPH-binding domain KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 BWK49_RS20935 4081b22105196b98f48406920998cc43 333 Hamap MF_00435 Ketol-acid reductoisomerase [ilvC]. 1 326 43.908 T 06-07-2017 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 BWK49_RS20935 4081b22105196b98f48406920998cc43 333 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 181 324 2.4E-61 T 06-07-2017 IPR000506 Acetohydroxy acid isomeroreductase C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 BWK49_RS20935 4081b22105196b98f48406920998cc43 333 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 12 324 2.4E-120 T 06-07-2017 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 BWK49_RS20935 4081b22105196b98f48406920998cc43 333 Gene3D G3DSA:1.10.1040.10 27 323 8.8E-105 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 BWK49_RS13345 c1e93279f9bdafbd4730537a5a3b3db7 93 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 7 93 17.844 T 06-07-2017 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 BWK49_RS13345 c1e93279f9bdafbd4730537a5a3b3db7 93 SUPERFAMILY SSF101386 8 93 8.97E-21 T 06-07-2017 BWK49_RS13345 c1e93279f9bdafbd4730537a5a3b3db7 93 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 11 93 6.8E-22 T 06-07-2017 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 BWK49_RS13345 c1e93279f9bdafbd4730537a5a3b3db7 93 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 8 92 3.4E-8 T 06-07-2017 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 BWK49_RS15830 0eb71930fb13f079e668fd6bf7ac1385 341 Gene3D G3DSA:1.10.540.10 35 83 1.2E-7 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS15830 0eb71930fb13f079e668fd6bf7ac1385 341 SUPERFAMILY SSF56645 33 153 3.66E-9 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS15830 0eb71930fb13f079e668fd6bf7ac1385 341 SUPERFAMILY SSF47203 190 324 2.74E-23 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS15830 0eb71930fb13f079e668fd6bf7ac1385 341 Gene3D G3DSA:1.20.140.10 190 314 5.6E-20 T 06-07-2017 BWK49_RS15830 0eb71930fb13f079e668fd6bf7ac1385 341 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 29 92 3.1E-6 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS15830 0eb71930fb13f079e668fd6bf7ac1385 341 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 173 310 3.2E-15 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS21810 2e9b7c16b2a7a2a4e2f89211cde699d8 281 SUPERFAMILY SSF109854 9 164 1.25E-30 T 06-07-2017 BWK49_RS21810 2e9b7c16b2a7a2a4e2f89211cde699d8 281 Pfam PF07398 MDMPI C-terminal domain 177 270 3.0E-12 T 06-07-2017 IPR010872 MDMPI C-terminal BWK49_RS21810 2e9b7c16b2a7a2a4e2f89211cde699d8 281 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 20 158 9.7E-32 T 06-07-2017 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 BWK49_RS21810 2e9b7c16b2a7a2a4e2f89211cde699d8 281 Gene3D G3DSA:1.20.120.450 3 138 5.1E-10 T 06-07-2017 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase BWK49_RS21810 2e9b7c16b2a7a2a4e2f89211cde699d8 281 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 19 251 1.7E-42 T 06-07-2017 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type BWK49_RS28380 79ab7058badb2d89281f9bd96dd3c457 116 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 22 88 1.5E-27 T 06-07-2017 IPR002696 Putative membrane protein insertion efficiency factor BWK49_RS28380 79ab7058badb2d89281f9bd96dd3c457 116 SMART SM01234 18 85 1.4E-36 T 06-07-2017 IPR002696 Putative membrane protein insertion efficiency factor BWK49_RS28380 79ab7058badb2d89281f9bd96dd3c457 116 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 18 86 23.514 T 06-07-2017 IPR002696 Putative membrane protein insertion efficiency factor BWK49_RS28380 79ab7058badb2d89281f9bd96dd3c457 116 Pfam PF01809 Haemolytic domain 22 85 1.1E-26 T 06-07-2017 IPR002696 Putative membrane protein insertion efficiency factor BWK49_RS28380 79ab7058badb2d89281f9bd96dd3c457 116 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 32 85 5.0E-25 T 06-07-2017 IPR002696 Putative membrane protein insertion efficiency factor BWK49_RS22945 bb0f6f35352b23f5d72466f247698e9c 198 SUPERFAMILY SSF46689 7 77 3.49E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS22945 bb0f6f35352b23f5d72466f247698e9c 198 Gene3D G3DSA:1.10.357.10 12 185 4.8E-20 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS22945 bb0f6f35352b23f5d72466f247698e9c 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 59 5.0E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS02010 d1d628682e09fa887b9ffccaf75df48d 213 SUPERFAMILY SSF48498 88 206 2.89E-11 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS02010 d1d628682e09fa887b9ffccaf75df48d 213 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 72 5.2E-12 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS02010 d1d628682e09fa887b9ffccaf75df48d 213 Pfam PF16859 Bacterial transcriptional repressor C-terminal 84 200 8.7E-9 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS02010 d1d628682e09fa887b9ffccaf75df48d 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 40 8.5E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS02010 d1d628682e09fa887b9ffccaf75df48d 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 48 71 8.5E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS02010 d1d628682e09fa887b9ffccaf75df48d 213 Gene3D G3DSA:1.10.10.60 17 70 4.0E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS02010 d1d628682e09fa887b9ffccaf75df48d 213 SUPERFAMILY SSF46689 17 81 6.48E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS02010 d1d628682e09fa887b9ffccaf75df48d 213 Gene3D G3DSA:1.10.357.10 71 206 4.4E-14 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS07840 9e12afefcf077183ef5994a1b24dc364 265 Pfam PF01738 Dienelactone hydrolase family 29 262 2.1E-8 T 06-07-2017 IPR002925 Dienelactone hydrolase GO:0016787 BWK49_RS07840 9e12afefcf077183ef5994a1b24dc364 265 Gene3D G3DSA:3.40.50.1820 25 261 1.5E-15 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS07840 9e12afefcf077183ef5994a1b24dc364 265 SUPERFAMILY SSF53474 184 262 8.65E-14 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS07840 9e12afefcf077183ef5994a1b24dc364 265 SUPERFAMILY SSF53474 17 156 8.65E-14 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS19730 e2c2e5efe384c70e17f427f56b3a8777 276 SUPERFAMILY SSF54637 18 113 2.05E-8 T 06-07-2017 IPR029069 HotDog domain BWK49_RS19730 e2c2e5efe384c70e17f427f56b3a8777 276 Pfam PF13622 Thioesterase-like superfamily 48 260 9.0E-23 T 06-07-2017 BWK49_RS19730 e2c2e5efe384c70e17f427f56b3a8777 276 Gene3D G3DSA:3.10.129.10 61 107 8.0E-7 T 06-07-2017 IPR029069 HotDog domain BWK49_RS13465 7f32f7e97174d193943568d3908fe06f 375 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 302 314 - T 06-07-2017 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site BWK49_RS13465 7f32f7e97174d193943568d3908fe06f 375 Pfam PF01321 Creatinase/Prolidase N-terminal domain 14 146 8.2E-12 T 06-07-2017 IPR000587 Creatinase, N-terminal GO:0016787 BWK49_RS13465 7f32f7e97174d193943568d3908fe06f 375 Pfam PF00557 Metallopeptidase family M24 154 356 7.0E-62 T 06-07-2017 IPR000994 Peptidase M24, structural domain BWK49_RS13465 7f32f7e97174d193943568d3908fe06f 375 SUPERFAMILY SSF55920 145 372 5.1E-72 T 06-07-2017 IPR000994 Peptidase M24, structural domain BWK49_RS13465 7f32f7e97174d193943568d3908fe06f 375 Gene3D G3DSA:3.90.230.10 145 372 1.4E-71 T 06-07-2017 IPR000994 Peptidase M24, structural domain BWK49_RS13465 7f32f7e97174d193943568d3908fe06f 375 SUPERFAMILY SSF53092 5 144 8.11E-16 T 06-07-2017 IPR028980 Creatinase/Aminopeptidase P, N-terminal BWK49_RS13465 7f32f7e97174d193943568d3908fe06f 375 Gene3D G3DSA:3.40.350.10 4 124 4.5E-14 T 06-07-2017 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal BWK49_RS13850 9b5602051bd9bfc07aa946ef3bed9edb 323 SUPERFAMILY SSF51430 8 307 5.89E-100 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain BWK49_RS13850 9b5602051bd9bfc07aa946ef3bed9edb 323 Pfam PF00248 Aldo/keto reductase family 13 305 5.9E-79 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain BWK49_RS13850 9b5602051bd9bfc07aa946ef3bed9edb 323 PRINTS PR00069 Aldo-keto reductase signature 137 154 4.9E-6 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 BWK49_RS13850 9b5602051bd9bfc07aa946ef3bed9edb 323 PRINTS PR00069 Aldo-keto reductase signature 42 66 4.9E-6 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 BWK49_RS13850 9b5602051bd9bfc07aa946ef3bed9edb 323 PRINTS PR00069 Aldo-keto reductase signature 106 124 4.9E-6 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 BWK49_RS13850 9b5602051bd9bfc07aa946ef3bed9edb 323 Gene3D G3DSA:3.20.20.100 1 309 1.0E-109 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain BWK49_RS03380 103ce8f0298c50490552856c84432d2d 301 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 158 186 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS03380 103ce8f0298c50490552856c84432d2d 301 SUPERFAMILY SSF51735 5 259 5.88E-59 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS03380 103ce8f0298c50490552856c84432d2d 301 Pfam PF00106 short chain dehydrogenase 8 211 2.1E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS03380 103ce8f0298c50490552856c84432d2d 301 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 202 4.5E-5 T 06-07-2017 BWK49_RS03380 103ce8f0298c50490552856c84432d2d 301 Gene3D G3DSA:3.40.50.720 4 261 5.3E-65 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS03380 103ce8f0298c50490552856c84432d2d 301 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 190 5.6E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS03380 103ce8f0298c50490552856c84432d2d 301 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 92 103 5.6E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS03380 103ce8f0298c50490552856c84432d2d 301 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 192 209 5.6E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS03380 103ce8f0298c50490552856c84432d2d 301 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 5.6E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS03380 103ce8f0298c50490552856c84432d2d 301 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 161 5.6E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS03380 103ce8f0298c50490552856c84432d2d 301 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 92 103 1.3E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS03380 103ce8f0298c50490552856c84432d2d 301 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 171 190 1.3E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS03380 103ce8f0298c50490552856c84432d2d 301 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 159 1.3E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS24580 0d50cfc5a219a7b103f6d4d5b2ed878c 235 Gene3D G3DSA:3.30.190.20 161 226 1.0E-42 T 06-07-2017 IPR016094 Ribosomal protein L1, 2-layer alpha/beta-sandwich GO:0003723 BWK49_RS24580 0d50cfc5a219a7b103f6d4d5b2ed878c 235 Gene3D G3DSA:3.30.190.20 17 68 1.0E-42 T 06-07-2017 IPR016094 Ribosomal protein L1, 2-layer alpha/beta-sandwich GO:0003723 BWK49_RS24580 0d50cfc5a219a7b103f6d4d5b2ed878c 235 Pfam PF00687 Ribosomal protein L1p/L10e family 31 220 1.3E-51 T 06-07-2017 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein BWK49_RS24580 0d50cfc5a219a7b103f6d4d5b2ed878c 235 Gene3D G3DSA:3.40.50.790 69 159 5.0E-42 T 06-07-2017 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich BWK49_RS24580 0d50cfc5a219a7b103f6d4d5b2ed878c 235 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 226 2.7E-101 T 06-07-2017 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 BWK49_RS24580 0d50cfc5a219a7b103f6d4d5b2ed878c 235 PIRSF PIRSF002155 1 227 9.1E-72 T 06-07-2017 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 BWK49_RS24580 0d50cfc5a219a7b103f6d4d5b2ed878c 235 SUPERFAMILY SSF56808 6 226 5.49E-81 T 06-07-2017 IPR023674 Ribosomal protein L1-like BWK49_RS24580 0d50cfc5a219a7b103f6d4d5b2ed878c 235 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 229 41.718 T 06-07-2017 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 BWK49_RS24580 0d50cfc5a219a7b103f6d4d5b2ed878c 235 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 139 - T 06-07-2017 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 BWK49_RS23840 640c11da3f96bbef8fe377e0cc5e9d5c 341 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 4 315 2.9E-113 T 06-07-2017 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 BWK49_RS23840 640c11da3f96bbef8fe377e0cc5e9d5c 341 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 5 309 1.3E-86 T 06-07-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 BWK49_RS23840 640c11da3f96bbef8fe377e0cc5e9d5c 341 Pfam PF00814 Glycoprotease family 29 309 9.3E-88 T 06-07-2017 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 BWK49_RS23840 640c11da3f96bbef8fe377e0cc5e9d5c 341 ProSitePatterns PS01016 Glycoprotease family signature. 99 119 - T 06-07-2017 IPR017860 Peptidase M22, conserved site KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618|Reactome: R-HSA-6782315 BWK49_RS23840 640c11da3f96bbef8fe377e0cc5e9d5c 341 SUPERFAMILY SSF53067 104 309 3.99E-33 T 06-07-2017 BWK49_RS23840 640c11da3f96bbef8fe377e0cc5e9d5c 341 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 5 18 1.5E-50 T 06-07-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 BWK49_RS23840 640c11da3f96bbef8fe377e0cc5e9d5c 341 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 133 145 1.5E-50 T 06-07-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 BWK49_RS23840 640c11da3f96bbef8fe377e0cc5e9d5c 341 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 266 275 1.5E-50 T 06-07-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 BWK49_RS23840 640c11da3f96bbef8fe377e0cc5e9d5c 341 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 100 119 1.5E-50 T 06-07-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 BWK49_RS23840 640c11da3f96bbef8fe377e0cc5e9d5c 341 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 157 178 1.5E-50 T 06-07-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 BWK49_RS23840 640c11da3f96bbef8fe377e0cc5e9d5c 341 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 79 99 1.5E-50 T 06-07-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 BWK49_RS23840 640c11da3f96bbef8fe377e0cc5e9d5c 341 Gene3D G3DSA:3.30.420.40 3 146 3.6E-37 T 06-07-2017 BWK49_RS23840 640c11da3f96bbef8fe377e0cc5e9d5c 341 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 2 335 60.266 T 06-07-2017 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 BWK49_RS23840 640c11da3f96bbef8fe377e0cc5e9d5c 341 SUPERFAMILY SSF53067 4 124 2.2E-23 T 06-07-2017 BWK49_RS26975 8bd05899432b6a5d7a250c86b58364ea 469 TIGRFAM TIGR02946 acyl_WS_DGAT: acyltransferase, WS/DGAT/MGAT 4 453 7.1E-143 T 06-07-2017 IPR014292 Acyltransferase, WS/DGAT/MGAT GO:0016746|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 BWK49_RS26975 8bd05899432b6a5d7a250c86b58364ea 469 Pfam PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain 4 263 1.1E-80 T 06-07-2017 IPR004255 O-acyltransferase, WSD1, N-terminal GO:0004144|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 BWK49_RS26975 8bd05899432b6a5d7a250c86b58364ea 469 SUPERFAMILY SSF52777 32 166 8.56E-9 T 06-07-2017 BWK49_RS26975 8bd05899432b6a5d7a250c86b58364ea 469 Pfam PF06974 Protein of unknown function (DUF1298) 302 449 5.6E-34 T 06-07-2017 IPR009721 O-acyltransferase WSD1, C-terminal GO:0004144 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 BWK49_RS18270 18f31cb47b69e9884f3c491efff92cbd 476 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 3.2E-7 T 06-07-2017 BWK49_RS18270 18f31cb47b69e9884f3c491efff92cbd 476 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 209 234 3.2E-7 T 06-07-2017 BWK49_RS18270 18f31cb47b69e9884f3c491efff92cbd 476 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 209 227 6.5E-5 T 06-07-2017 BWK49_RS18270 18f31cb47b69e9884f3c491efff92cbd 476 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 6.5E-5 T 06-07-2017 BWK49_RS18270 18f31cb47b69e9884f3c491efff92cbd 476 SUPERFAMILY SSF51905 425 469 2.37E-32 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS18270 18f31cb47b69e9884f3c491efff92cbd 476 SUPERFAMILY SSF51905 2 301 2.37E-32 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS18270 18f31cb47b69e9884f3c491efff92cbd 476 Gene3D G3DSA:3.50.50.60 3 86 4.8E-17 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS18270 18f31cb47b69e9884f3c491efff92cbd 476 Pfam PF13450 NAD(P)-binding Rossmann-like domain 6 56 3.7E-11 T 06-07-2017 BWK49_RS18270 18f31cb47b69e9884f3c491efff92cbd 476 Gene3D G3DSA:3.50.50.60 196 280 1.5E-6 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS18270 18f31cb47b69e9884f3c491efff92cbd 476 Gene3D G3DSA:3.50.50.60 436 475 1.5E-6 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS19855 d0e5af94b25b4fc97b0354307c6e2fec 296 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 25 180 3.7E-50 T 06-07-2017 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 BWK49_RS19855 d0e5af94b25b4fc97b0354307c6e2fec 296 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 5 219 1.2E-65 T 06-07-2017 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 BWK49_RS19855 d0e5af94b25b4fc97b0354307c6e2fec 296 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 181 221 1.1E-11 T 06-07-2017 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 BWK49_RS19855 d0e5af94b25b4fc97b0354307c6e2fec 296 Pfam PF09142 tRNA Pseudouridine synthase II, C terminal 237 292 8.6E-22 T 06-07-2017 IPR015225 tRNA pseudouridine synthase II, TruB, subfamily 2, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 BWK49_RS19855 d0e5af94b25b4fc97b0354307c6e2fec 296 SUPERFAMILY SSF88697 237 293 4.08E-15 T 06-07-2017 IPR015947 PUA-like domain BWK49_RS19855 d0e5af94b25b4fc97b0354307c6e2fec 296 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 3 289 16.926 T 06-07-2017 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 BWK49_RS19855 d0e5af94b25b4fc97b0354307c6e2fec 296 SUPERFAMILY SSF55120 5 223 6.72E-72 T 06-07-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 BWK49_RS28085 e6db55a106154f8b9e4fce687ca5edfe 276 Pfam PF00561 alpha/beta hydrolase fold 23 256 2.3E-12 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS28085 e6db55a106154f8b9e4fce687ca5edfe 276 SUPERFAMILY SSF53474 1 269 1.22E-44 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS28085 e6db55a106154f8b9e4fce687ca5edfe 276 Gene3D G3DSA:3.40.50.1820 3 269 1.9E-44 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS01195 18db9c556c283e52c77537847d1d52fd 152 SUPERFAMILY SSF49879 33 147 8.23E-30 T 06-07-2017 IPR008984 SMAD/FHA domain GO:0005515 BWK49_RS01195 18db9c556c283e52c77537847d1d52fd 152 SMART SM00240 76 126 8.0E-12 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 BWK49_RS01195 18db9c556c283e52c77537847d1d52fd 152 Pfam PF16697 Inner membrane component of T3SS, cytoplasmic domain 62 148 2.8E-18 T 06-07-2017 IPR032030 YscD, cytoplasmic domain BWK49_RS01195 18db9c556c283e52c77537847d1d52fd 152 Gene3D G3DSA:2.60.200.20 55 147 8.0E-28 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 BWK49_RS01105 02dc2ab6d8b3b041a7db502707ff6167 255 Gene3D G3DSA:3.40.1130.10 27 183 6.3E-15 T 06-07-2017 BWK49_RS01105 02dc2ab6d8b3b041a7db502707ff6167 255 SMART SM00563 38 152 2.8E-36 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 BWK49_RS01105 02dc2ab6d8b3b041a7db502707ff6167 255 Pfam PF01553 Acyltransferase 23 149 2.0E-31 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 BWK49_RS01105 02dc2ab6d8b3b041a7db502707ff6167 255 SUPERFAMILY SSF69593 13 206 1.7E-32 T 06-07-2017 BWK49_RS07505 9789fedf830a0bd39276abcf17d87416 326 Gene3D G3DSA:1.10.287.1080 86 153 1.1E-8 T 06-07-2017 BWK49_RS07505 9789fedf830a0bd39276abcf17d87416 326 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 107 181 2.9E-22 T 06-07-2017 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core BWK49_RS07505 9789fedf830a0bd39276abcf17d87416 326 SUPERFAMILY SSF101386 90 182 6.54E-17 T 06-07-2017 BWK49_RS22630 2cb52df9fe567fdba346bf4735f2191b 84 TIGRFAM TIGR02200 GlrX_actino: glutaredoxin-like protein 6 81 1.1E-40 T 06-07-2017 IPR011915 Glutaredoxin-like protein, actinobacteria BWK49_RS22630 2cb52df9fe567fdba346bf4735f2191b 84 Gene3D G3DSA:3.40.30.10 5 80 2.3E-19 T 06-07-2017 IPR012336 Thioredoxin-like fold BWK49_RS22630 2cb52df9fe567fdba346bf4735f2191b 84 ProSitePatterns PS00194 Thioredoxin family active site. 6 24 - T 06-07-2017 IPR017937 Thioredoxin, conserved site GO:0045454 BWK49_RS22630 2cb52df9fe567fdba346bf4735f2191b 84 SUPERFAMILY SSF52833 5 79 5.77E-17 T 06-07-2017 IPR012336 Thioredoxin-like fold BWK49_RS22630 2cb52df9fe567fdba346bf4735f2191b 84 Pfam PF00462 Glutaredoxin 7 61 2.8E-13 T 06-07-2017 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 BWK49_RS25820 fc4e5ec5f2ef8ec7eaef43a6cc4cb3a5 406 Pfam PF13704 Glycosyl transferase family 2 11 101 1.5E-7 T 06-07-2017 BWK49_RS25820 fc4e5ec5f2ef8ec7eaef43a6cc4cb3a5 406 Gene3D G3DSA:2.70.70.10 244 374 3.4E-26 T 06-07-2017 BWK49_RS25820 fc4e5ec5f2ef8ec7eaef43a6cc4cb3a5 406 Pfam PF01551 Peptidase family M23 275 369 8.1E-18 T 06-07-2017 IPR016047 Peptidase M23 BWK49_RS25820 fc4e5ec5f2ef8ec7eaef43a6cc4cb3a5 406 Gene3D G3DSA:3.90.550.10 6 60 1.2E-4 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases BWK49_RS25820 fc4e5ec5f2ef8ec7eaef43a6cc4cb3a5 406 SUPERFAMILY SSF53448 1 211 1.49E-11 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases BWK49_RS25820 fc4e5ec5f2ef8ec7eaef43a6cc4cb3a5 406 SUPERFAMILY SSF51261 262 373 1.15E-23 T 06-07-2017 IPR011055 Duplicated hybrid motif BWK49_RS04610 663d04fa9f00ddcf0ff60a9482a9d62f 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 66 1.2E-13 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS04610 663d04fa9f00ddcf0ff60a9482a9d62f 199 Gene3D G3DSA:1.10.357.10 63 192 5.3E-10 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS04610 663d04fa9f00ddcf0ff60a9482a9d62f 199 SUPERFAMILY SSF46689 8 86 2.1E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS04610 663d04fa9f00ddcf0ff60a9482a9d62f 199 Gene3D G3DSA:1.10.10.60 10 62 1.8E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS04610 663d04fa9f00ddcf0ff60a9482a9d62f 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 1.3E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS04610 663d04fa9f00ddcf0ff60a9482a9d62f 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 1.3E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS05165 dcec2e5f2c91df514fc161d28dfbf3ef 482 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 49 423 1.3E-111 T 06-07-2017 IPR030931 Group II intron reverse transcriptase/maturase BWK49_RS05165 dcec2e5f2c91df514fc161d28dfbf3ef 482 SUPERFAMILY SSF56672 33 409 4.77E-46 T 06-07-2017 BWK49_RS05165 dcec2e5f2c91df514fc161d28dfbf3ef 482 Pfam PF08388 Group II intron, maturase-specific domain 360 425 8.4E-23 T 06-07-2017 IPR013597 Group II intron, maturase-specific BWK49_RS05165 dcec2e5f2c91df514fc161d28dfbf3ef 482 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 106 336 5.7E-37 T 06-07-2017 IPR000477 Reverse transcriptase domain BWK49_RS11850 47adb67346f8becf6f5dddb875e03533 137 SUPERFAMILY SSF54427 1 124 7.76E-27 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS11850 47adb67346f8becf6f5dddb875e03533 137 Pfam PF07858 Limonene-1,2-epoxide hydrolase catalytic domain 3 122 2.1E-23 T 06-07-2017 IPR013100 Limonene-1,2-epoxide hydrolase BWK49_RS11850 47adb67346f8becf6f5dddb875e03533 137 Gene3D G3DSA:3.10.450.50 1 122 4.3E-32 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS09395 3e68d3301cc1baf7a179c2403f5beecf 335 Gene3D G3DSA:2.102.10.10 11 125 1.6E-29 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS09395 3e68d3301cc1baf7a179c2403f5beecf 335 SUPERFAMILY SSF50022 10 121 4.06E-29 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS09395 3e68d3301cc1baf7a179c2403f5beecf 335 SUPERFAMILY SSF55961 133 327 8.24E-10 T 06-07-2017 BWK49_RS09395 3e68d3301cc1baf7a179c2403f5beecf 335 Pfam PF00355 Rieske [2Fe-2S] domain 12 94 4.1E-14 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS24475 9b74bc936c8fbca2cc298b0cc7f67424 279 Pfam PF10503 Esterase PHB depolymerase 46 187 7.8E-15 T 06-07-2017 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 BWK49_RS24475 9b74bc936c8fbca2cc298b0cc7f67424 279 SUPERFAMILY SSF53474 40 203 8.88E-23 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS24475 9b74bc936c8fbca2cc298b0cc7f67424 279 SUPERFAMILY SSF53474 250 277 8.88E-23 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS24475 9b74bc936c8fbca2cc298b0cc7f67424 279 Gene3D G3DSA:3.40.50.1820 11 279 3.8E-41 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS26745 b506fd9b7ddd80d28d95e16572482acb 1402 Gene3D G3DSA:2.60.120.260 713 800 1.3E-7 T 06-07-2017 IPR008979 Galactose-binding domain-like BWK49_RS26745 b506fd9b7ddd80d28d95e16572482acb 1402 SUPERFAMILY SSF49785 957 1085 3.71E-7 T 06-07-2017 IPR008979 Galactose-binding domain-like BWK49_RS26745 b506fd9b7ddd80d28d95e16572482acb 1402 Gene3D G3DSA:2.60.120.260 958 1059 6.6E-5 T 06-07-2017 IPR008979 Galactose-binding domain-like BWK49_RS26745 b506fd9b7ddd80d28d95e16572482acb 1402 SUPERFAMILY SSF49785 712 832 1.16E-11 T 06-07-2017 IPR008979 Galactose-binding domain-like BWK49_RS26745 b506fd9b7ddd80d28d95e16572482acb 1402 Pfam PF11847 Domain of unknown function (DUF3367) 13 695 1.1E-282 T 06-07-2017 IPR021798 Protein of unknown function DUF3367 MetaCyc: PWY-6397 BWK49_RS19265 63adc34cf11d5c3a8a05cee5acda937d 251 Pfam PF01872 RibD C-terminal domain 33 244 7.6E-44 T 06-07-2017 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 BWK49_RS19265 63adc34cf11d5c3a8a05cee5acda937d 251 Gene3D G3DSA:3.40.430.10 24 250 7.0E-57 T 06-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 BWK49_RS19265 63adc34cf11d5c3a8a05cee5acda937d 251 SUPERFAMILY SSF53597 32 250 1.96E-39 T 06-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 BWK49_RS15000 3bf6de91ba6d5df76aec0d452c5db1d4 316 Gene3D G3DSA:3.30.2010.10 141 197 9.3E-12 T 06-07-2017 BWK49_RS15000 3bf6de91ba6d5df76aec0d452c5db1d4 316 Pfam PF01435 Peptidase family M48 141 209 1.1E-10 T 06-07-2017 IPR001915 Peptidase M48 GO:0004222|GO:0006508 BWK49_RS20410 162f3711456c2046bc9d13df5fa64f4a 179 Pfam PF02620 Uncharacterized ACR, COG1399 56 167 1.0E-28 T 06-07-2017 IPR003772 Protein of unknown function DUF177 BWK49_RS27145 8e64964be3e6c2d460006dc47ed1ee9e 327 SUPERFAMILY SSF51412 3 255 4.76E-42 T 06-07-2017 BWK49_RS27145 8e64964be3e6c2d460006dc47ed1ee9e 327 Pfam PF03060 Nitronate monooxygenase 65 324 2.4E-28 T 06-07-2017 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 BWK49_RS27145 8e64964be3e6c2d460006dc47ed1ee9e 327 Gene3D G3DSA:3.20.20.70 3 215 2.2E-44 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 BWK49_RS15550 f2306c7940a164e4e78750de0c3d24f7 322 Gene3D G3DSA:3.90.226.10 6 262 1.6E-45 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS15550 f2306c7940a164e4e78750de0c3d24f7 322 SUPERFAMILY SSF52096 15 254 8.96E-39 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS15550 f2306c7940a164e4e78750de0c3d24f7 322 Pfam PF00378 Enoyl-CoA hydratase/isomerase 130 257 3.4E-13 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 BWK49_RS15550 f2306c7940a164e4e78750de0c3d24f7 322 Pfam PF00378 Enoyl-CoA hydratase/isomerase 23 83 1.9E-9 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 BWK49_RS03755 3db9c8411b0f52cf9843f0dee3401892 239 SUPERFAMILY SSF52172 7 132 2.42E-42 T 06-07-2017 IPR011006 CheY-like superfamily BWK49_RS03755 3db9c8411b0f52cf9843f0dee3401892 239 Gene3D G3DSA:1.10.10.10 138 238 1.2E-32 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS03755 3db9c8411b0f52cf9843f0dee3401892 239 Pfam PF00486 Transcriptional regulatory protein, C terminal 161 235 4.0E-23 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 BWK49_RS03755 3db9c8411b0f52cf9843f0dee3401892 239 Gene3D G3DSA:3.40.50.2300 6 132 1.0E-40 T 06-07-2017 BWK49_RS03755 3db9c8411b0f52cf9843f0dee3401892 239 Pfam PF00072 Response regulator receiver domain 15 124 2.4E-27 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 BWK49_RS03755 3db9c8411b0f52cf9843f0dee3401892 239 SMART SM00448 13 124 6.0E-44 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 BWK49_RS03755 3db9c8411b0f52cf9843f0dee3401892 239 SMART SM00862 161 235 1.5E-23 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 BWK49_RS03755 3db9c8411b0f52cf9843f0dee3401892 239 SUPERFAMILY SSF46894 138 236 1.19E-26 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 BWK49_RS05350 05b69a2cc2cfde86afdbf83fc19c5718 391 Gene3D G3DSA:3.40.47.10 154 191 3.5E-47 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS05350 05b69a2cc2cfde86afdbf83fc19c5718 391 Gene3D G3DSA:3.40.47.10 275 390 3.5E-47 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS05350 05b69a2cc2cfde86afdbf83fc19c5718 391 SUPERFAMILY SSF53901 5 268 3.95E-68 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS05350 05b69a2cc2cfde86afdbf83fc19c5718 391 SUPERFAMILY SSF53901 271 390 1.87E-36 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS05350 05b69a2cc2cfde86afdbf83fc19c5718 391 Gene3D G3DSA:3.40.47.10 6 126 1.1E-62 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS05350 05b69a2cc2cfde86afdbf83fc19c5718 391 Gene3D G3DSA:3.40.47.10 192 274 1.1E-62 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS05350 05b69a2cc2cfde86afdbf83fc19c5718 391 Pfam PF02803 Thiolase, C-terminal domain 271 390 1.1E-36 T 06-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 BWK49_RS05350 05b69a2cc2cfde86afdbf83fc19c5718 391 Pfam PF00108 Thiolase, N-terminal domain 7 260 3.4E-65 T 06-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 BWK49_RS05350 05b69a2cc2cfde86afdbf83fc19c5718 391 ProSitePatterns PS00737 Thiolases signature 2. 337 353 - T 06-07-2017 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 BWK49_RS05350 05b69a2cc2cfde86afdbf83fc19c5718 391 PIRSF PIRSF000429 1 391 1.4E-115 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 BWK49_RS05350 05b69a2cc2cfde86afdbf83fc19c5718 391 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 8 389 4.5E-121 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 BWK49_RS00780 0ec6f7fafd2201b0977179c6e8a3da4e 239 PRINTS PR00502 NUDIX hydrolase family signature 111 126 8.9E-8 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 BWK49_RS00780 0ec6f7fafd2201b0977179c6e8a3da4e 239 PRINTS PR00502 NUDIX hydrolase family signature 97 111 8.9E-8 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 BWK49_RS00780 0ec6f7fafd2201b0977179c6e8a3da4e 239 SUPERFAMILY SSF55811 70 180 4.74E-27 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 BWK49_RS00780 0ec6f7fafd2201b0977179c6e8a3da4e 239 Pfam PF00293 NUDIX domain 78 177 1.0E-15 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 BWK49_RS00780 0ec6f7fafd2201b0977179c6e8a3da4e 239 Gene3D G3DSA:3.90.79.10 16 40 5.0E-30 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 BWK49_RS00780 0ec6f7fafd2201b0977179c6e8a3da4e 239 Gene3D G3DSA:3.90.79.10 74 212 5.0E-30 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 BWK49_RS00780 0ec6f7fafd2201b0977179c6e8a3da4e 239 ProSitePatterns PS00893 Nudix box signature. 102 123 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 BWK49_RS02685 5a1fe50c440b74cccb9c71a8fad6ae68 136 SMART SM00387 34 134 5.5E-9 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS02685 5a1fe50c440b74cccb9c71a8fad6ae68 136 Gene3D G3DSA:3.30.565.10 18 130 1.2E-15 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS02685 5a1fe50c440b74cccb9c71a8fad6ae68 136 Pfam PF13581 Histidine kinase-like ATPase domain 12 129 3.6E-9 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS02685 5a1fe50c440b74cccb9c71a8fad6ae68 136 SUPERFAMILY SSF55874 25 128 2.19E-16 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS11820 5f782e8be669a02497835460aedb18e7 360 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 86 106 1.1E-6 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS11820 5f782e8be669a02497835460aedb18e7 360 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 15 40 1.1E-6 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS11820 5f782e8be669a02497835460aedb18e7 360 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 45 60 1.1E-6 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS11820 5f782e8be669a02497835460aedb18e7 360 Pfam PF00355 Rieske [2Fe-2S] domain 34 112 1.6E-15 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS11820 5f782e8be669a02497835460aedb18e7 360 Gene3D G3DSA:3.90.380.10 132 340 4.0E-8 T 06-07-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 BWK49_RS11820 5f782e8be669a02497835460aedb18e7 360 SUPERFAMILY SSF50022 4 140 1.7E-38 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS11820 5f782e8be669a02497835460aedb18e7 360 SUPERFAMILY SSF55961 147 356 3.14E-27 T 06-07-2017 BWK49_RS11820 5f782e8be669a02497835460aedb18e7 360 ProSitePatterns PS00570 Bacterial ring hydroxylating dioxygenases alpha-subunit signature. 73 95 - T 06-07-2017 IPR015881 Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site GO:0005506|GO:0016705|GO:0051537|GO:0055114 BWK49_RS11820 5f782e8be669a02497835460aedb18e7 360 Gene3D G3DSA:2.102.10.10 30 131 4.9E-30 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS11820 5f782e8be669a02497835460aedb18e7 360 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 179 353 1.4E-19 T 06-07-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 BWK49_RS05865 2806f7234beed227539c1adb27f84677 276 Gene3D G3DSA:3.40.50.970 1 271 2.3E-41 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS05865 2806f7234beed227539c1adb27f84677 276 SUPERFAMILY SSF52518 1 268 1.52E-30 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS05865 2806f7234beed227539c1adb27f84677 276 Pfam PF00676 Dehydrogenase E1 component 26 258 1.0E-28 T 06-07-2017 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 BWK49_RS24230 aa812fe62502550a8792056c7ff81c7b 122 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 8 122 26.549 T 06-07-2017 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS24230 aa812fe62502550a8792056c7ff81c7b 122 Gene3D G3DSA:3.30.420.100 26 122 2.9E-35 T 06-07-2017 BWK49_RS24230 aa812fe62502550a8792056c7ff81c7b 122 SUPERFAMILY SSF53137 9 120 3.71E-46 T 06-07-2017 BWK49_RS24230 aa812fe62502550a8792056c7ff81c7b 122 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 11 122 8.3E-37 T 06-07-2017 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS24230 aa812fe62502550a8792056c7ff81c7b 122 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 8 122 2.0E-46 T 06-07-2017 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS02855 04461e907bb1f2a75b24ba445a2434cb 539 SMART SM00382 316 509 2.3E-18 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS02855 04461e907bb1f2a75b24ba445a2434cb 539 SMART SM00382 33 230 5.3E-18 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS02855 04461e907bb1f2a75b24ba445a2434cb 539 SUPERFAMILY SSF52540 6 259 3.07E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS02855 04461e907bb1f2a75b24ba445a2434cb 539 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 BWK49_RS02855 04461e907bb1f2a75b24ba445a2434cb 539 ProSitePatterns PS00211 ABC transporters family signature. 432 446 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 BWK49_RS02855 04461e907bb1f2a75b24ba445a2434cb 539 Gene3D G3DSA:3.40.50.300 7 254 7.8E-69 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS02855 04461e907bb1f2a75b24ba445a2434cb 539 Gene3D G3DSA:3.40.50.300 281 533 3.0E-76 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS02855 04461e907bb1f2a75b24ba445a2434cb 539 SUPERFAMILY SSF52540 284 531 1.64E-66 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS02855 04461e907bb1f2a75b24ba445a2434cb 539 Pfam PF00005 ABC transporter 26 181 1.8E-25 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 BWK49_RS02855 04461e907bb1f2a75b24ba445a2434cb 539 Pfam PF00005 ABC transporter 308 459 4.5E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 BWK49_RS02855 04461e907bb1f2a75b24ba445a2434cb 539 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 232 264 0.0011 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 BWK49_RS02855 04461e907bb1f2a75b24ba445a2434cb 539 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 511 538 5.5E-5 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 BWK49_RS00965 adb098baecc5042f7bbdca263bb29217 489 Pfam PF00743 Flavin-binding monooxygenase-like 81 212 4.6E-8 T 06-07-2017 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 BWK49_RS00965 adb098baecc5042f7bbdca263bb29217 489 Gene3D G3DSA:3.50.50.60 2 215 6.4E-51 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS00965 adb098baecc5042f7bbdca263bb29217 489 Gene3D G3DSA:3.50.50.60 322 471 5.0E-7 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS00965 adb098baecc5042f7bbdca263bb29217 489 Pfam PF13450 NAD(P)-binding Rossmann-like domain 9 56 1.1E-7 T 06-07-2017 BWK49_RS00965 adb098baecc5042f7bbdca263bb29217 489 SUPERFAMILY SSF51905 1 384 2.36E-51 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS22555 3f3de496362ef52fd8eccba0352bed81 518 Pfam PF05199 GMC oxidoreductase 374 508 1.2E-31 T 06-07-2017 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 BWK49_RS22555 3f3de496362ef52fd8eccba0352bed81 518 SUPERFAMILY SSF54373 301 458 5.76E-26 T 06-07-2017 BWK49_RS22555 3f3de496362ef52fd8eccba0352bed81 518 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 263 277 - T 06-07-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 BWK49_RS22555 3f3de496362ef52fd8eccba0352bed81 518 ProSitePatterns PS00623 GMC oxidoreductases signature 1. 86 109 - T 06-07-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 BWK49_RS22555 3f3de496362ef52fd8eccba0352bed81 518 SUPERFAMILY SSF51905 457 517 1.88E-74 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS22555 3f3de496362ef52fd8eccba0352bed81 518 SUPERFAMILY SSF51905 9 297 1.88E-74 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS22555 3f3de496362ef52fd8eccba0352bed81 518 Gene3D G3DSA:3.50.50.60 451 516 5.7E-107 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS22555 3f3de496362ef52fd8eccba0352bed81 518 Gene3D G3DSA:3.50.50.60 8 131 5.7E-107 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS22555 3f3de496362ef52fd8eccba0352bed81 518 Gene3D G3DSA:3.50.50.60 196 322 5.7E-107 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS22555 3f3de496362ef52fd8eccba0352bed81 518 Pfam PF00732 GMC oxidoreductase 10 304 4.4E-69 T 06-07-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 BWK49_RS07455 ac3f6f8f89a6a50a9fac04b9854c43c6 1098 Gene3D G3DSA:3.30.70.1230 22 195 1.2E-28 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 BWK49_RS07455 ac3f6f8f89a6a50a9fac04b9854c43c6 1098 SMART SM00421 1037 1094 4.1E-23 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS07455 ac3f6f8f89a6a50a9fac04b9854c43c6 1098 PRINTS PR00364 Disease resistance protein signature 232 247 1.1E-5 T 06-07-2017 BWK49_RS07455 ac3f6f8f89a6a50a9fac04b9854c43c6 1098 PRINTS PR00364 Disease resistance protein signature 396 410 1.1E-5 T 06-07-2017 BWK49_RS07455 ac3f6f8f89a6a50a9fac04b9854c43c6 1098 PRINTS PR00364 Disease resistance protein signature 301 315 1.1E-5 T 06-07-2017 BWK49_RS07455 ac3f6f8f89a6a50a9fac04b9854c43c6 1098 ProSitePatterns PS00622 LuxR-type HTH domain signature. 1054 1081 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS07455 ac3f6f8f89a6a50a9fac04b9854c43c6 1098 Gene3D G3DSA:3.40.50.300 214 352 1.2E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS07455 ac3f6f8f89a6a50a9fac04b9854c43c6 1098 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 1070 1082 8.5E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS07455 ac3f6f8f89a6a50a9fac04b9854c43c6 1098 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 1040 1054 8.5E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS07455 ac3f6f8f89a6a50a9fac04b9854c43c6 1098 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 1054 1070 8.5E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS07455 ac3f6f8f89a6a50a9fac04b9854c43c6 1098 Gene3D G3DSA:1.25.40.10 672 981 4.7E-15 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 BWK49_RS07455 ac3f6f8f89a6a50a9fac04b9854c43c6 1098 SUPERFAMILY SSF55073 22 196 5.97E-38 T 06-07-2017 IPR029787 Nucleotide cyclase BWK49_RS07455 ac3f6f8f89a6a50a9fac04b9854c43c6 1098 SUPERFAMILY SSF48452 753 932 4.46E-6 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 BWK49_RS07455 ac3f6f8f89a6a50a9fac04b9854c43c6 1098 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 22 152 7.7E-9 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 BWK49_RS07455 ac3f6f8f89a6a50a9fac04b9854c43c6 1098 SUPERFAMILY SSF46894 1032 1095 2.72E-17 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 BWK49_RS07455 ac3f6f8f89a6a50a9fac04b9854c43c6 1098 Gene3D G3DSA:1.10.10.10 1027 1096 6.1E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS07455 ac3f6f8f89a6a50a9fac04b9854c43c6 1098 SUPERFAMILY SSF52540 206 463 4.88E-19 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS07455 ac3f6f8f89a6a50a9fac04b9854c43c6 1098 SMART SM00044 5 165 0.0063 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 BWK49_RS07455 ac3f6f8f89a6a50a9fac04b9854c43c6 1098 Pfam PF00196 Bacterial regulatory proteins, luxR family 1039 1093 6.6E-16 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS08150 1b5e86839bb484bb6ebae454215efaa9 270 SUPERFAMILY SSF52096 15 270 1.61E-70 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS08150 1b5e86839bb484bb6ebae454215efaa9 270 Pfam PF00378 Enoyl-CoA hydratase/isomerase 20 270 1.2E-48 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 BWK49_RS08150 1b5e86839bb484bb6ebae454215efaa9 270 Gene3D G3DSA:3.90.226.10 16 268 2.1E-67 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS07990 3dd9152a84e223d78765d5628fb42dd3 300 SUPERFAMILY SSF53474 4 297 5.65E-53 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS07990 3dd9152a84e223d78765d5628fb42dd3 300 Gene3D G3DSA:3.40.50.1820 5 296 2.9E-58 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS07990 3dd9152a84e223d78765d5628fb42dd3 300 Pfam PF00561 alpha/beta hydrolase fold 30 284 1.3E-18 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS07990 3dd9152a84e223d78765d5628fb42dd3 300 PRINTS PR00412 Epoxide hydrolase signature 99 112 1.4E-20 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS07990 3dd9152a84e223d78765d5628fb42dd3 300 PRINTS PR00412 Epoxide hydrolase signature 33 51 1.4E-20 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS07990 3dd9152a84e223d78765d5628fb42dd3 300 PRINTS PR00412 Epoxide hydrolase signature 273 295 1.4E-20 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS07990 3dd9152a84e223d78765d5628fb42dd3 300 PRINTS PR00412 Epoxide hydrolase signature 53 68 1.4E-20 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS15565 12788090ab66372c1fef825ecf19981f 227 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 62 7.1E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS15565 12788090ab66372c1fef825ecf19981f 227 Gene3D G3DSA:1.10.357.10 10 203 6.8E-26 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS15565 12788090ab66372c1fef825ecf19981f 227 SUPERFAMILY SSF46689 2 80 1.23E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS15565 12788090ab66372c1fef825ecf19981f 227 SUPERFAMILY SSF48498 107 199 1.78E-5 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS01165 26e2156fb4e3f5e8cf608714b2a2044e 336 Gene3D G3DSA:3.40.50.1820 61 218 1.2E-46 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS01165 26e2156fb4e3f5e8cf608714b2a2044e 336 Gene3D G3DSA:3.40.50.1820 253 327 1.2E-46 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS01165 26e2156fb4e3f5e8cf608714b2a2044e 336 SMART SM01110 70 319 6.2E-59 T 06-07-2017 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 BWK49_RS01165 26e2156fb4e3f5e8cf608714b2a2044e 336 SUPERFAMILY SSF53474 71 276 5.67E-29 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS01165 26e2156fb4e3f5e8cf608714b2a2044e 336 Pfam PF01083 Cutinase 106 275 7.7E-14 T 06-07-2017 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 BWK49_RS19890 d36c5eb902b5e31f282803d4ab80a531 249 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 224 1.0E-50 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 BWK49_RS19890 d36c5eb902b5e31f282803d4ab80a531 249 SUPERFAMILY SSF52096 2 235 9.4E-68 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS19890 d36c5eb902b5e31f282803d4ab80a531 249 Gene3D G3DSA:3.90.226.10 2 220 1.5E-64 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS11340 50cbd3796b3e2eb582b09412d32ee820 248 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 8 222 8.6E-16 T 06-07-2017 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type BWK49_RS11340 50cbd3796b3e2eb582b09412d32ee820 248 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 9 134 8.8E-12 T 06-07-2017 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 BWK49_RS11340 50cbd3796b3e2eb582b09412d32ee820 248 Gene3D G3DSA:1.20.120.450 3 107 3.2E-7 T 06-07-2017 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase BWK49_RS11340 50cbd3796b3e2eb582b09412d32ee820 248 SUPERFAMILY SSF109854 2 135 4.73E-17 T 06-07-2017 BWK49_RS00690 23bd826000dd1989a1e428288e8125a0 140 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 31 140 1.1E-36 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 BWK49_RS00690 23bd826000dd1989a1e428288e8125a0 140 Pfam PF04075 Domain of unknown function (DUF385) 12 140 7.8E-45 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 BWK49_RS28345 feefcb21bc203336102780c3b6336fe7 407 Gene3D G3DSA:3.40.630.40 191 374 3.4E-36 T 06-07-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 BWK49_RS28345 feefcb21bc203336102780c3b6336fe7 407 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 194 371 8.0E-29 T 06-07-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 BWK49_RS28345 feefcb21bc203336102780c3b6336fe7 407 SMART SM00646 256 371 2.0E-33 T 06-07-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 BWK49_RS28345 feefcb21bc203336102780c3b6336fe7 407 SUPERFAMILY SSF47090 103 162 4.19E-18 T 06-07-2017 IPR002477 Peptidoglycan binding-like BWK49_RS28345 feefcb21bc203336102780c3b6336fe7 407 Gene3D G3DSA:1.10.101.10 106 164 6.7E-20 T 06-07-2017 IPR002477 Peptidoglycan binding-like BWK49_RS28345 feefcb21bc203336102780c3b6336fe7 407 Gene3D G3DSA:1.10.101.10 8 91 1.9E-20 T 06-07-2017 IPR002477 Peptidoglycan binding-like BWK49_RS28345 feefcb21bc203336102780c3b6336fe7 407 Pfam PF01471 Putative peptidoglycan binding domain 106 161 2.4E-16 T 06-07-2017 IPR002477 Peptidoglycan binding-like BWK49_RS28345 feefcb21bc203336102780c3b6336fe7 407 Pfam PF01471 Putative peptidoglycan binding domain 18 84 1.3E-11 T 06-07-2017 IPR002477 Peptidoglycan binding-like BWK49_RS28345 feefcb21bc203336102780c3b6336fe7 407 SUPERFAMILY SSF53187 191 374 1.54E-36 T 06-07-2017 BWK49_RS28345 feefcb21bc203336102780c3b6336fe7 407 SUPERFAMILY SSF47090 8 84 6.02E-13 T 06-07-2017 IPR002477 Peptidoglycan binding-like BWK49_RS26730 3c10d62f071882d00047dac7c9a93db8 383 Gene3D G3DSA:3.20.20.300 62 375 8.8E-75 T 06-07-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 BWK49_RS26730 3c10d62f071882d00047dac7c9a93db8 383 SUPERFAMILY SSF51445 63 375 1.02E-61 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily BWK49_RS26730 3c10d62f071882d00047dac7c9a93db8 383 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 57 373 1.1E-83 T 06-07-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 BWK49_RS25275 198f07e3f4146a8b63f30623c371b257 102 Pfam PF06013 Proteins of 100 residues with WXG 6 89 8.8E-18 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like BWK49_RS25275 198f07e3f4146a8b63f30623c371b257 102 SUPERFAMILY SSF140453 5 95 4.71E-17 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like BWK49_RS25275 198f07e3f4146a8b63f30623c371b257 102 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 6 92 1.2E-16 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like BWK49_RS25275 198f07e3f4146a8b63f30623c371b257 102 Gene3D G3DSA:1.10.287.1060 5 93 1.2E-16 T 06-07-2017 BWK49_RS03930 86cd2ca47275af94176deb068d0a62f4 79 TIGRFAM TIGR00302 TIGR00302: phosphoribosylformylglycinamidine synthase, purS protein 5 75 1.8E-14 T 06-07-2017 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 BWK49_RS03930 86cd2ca47275af94176deb068d0a62f4 79 Gene3D G3DSA:3.30.1280.10 3 77 4.5E-28 T 06-07-2017 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 BWK49_RS03930 86cd2ca47275af94176deb068d0a62f4 79 SUPERFAMILY SSF82697 3 77 3.49E-22 T 06-07-2017 BWK49_RS03930 86cd2ca47275af94176deb068d0a62f4 79 ProDom PD010362 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE PURS SYNTHETASE SYNTHASE COMPONENT SYNTHASE LIGASE FGAM UPF0062 I 11 74 3.0E-22 T 06-07-2017 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 BWK49_RS03930 86cd2ca47275af94176deb068d0a62f4 79 Hamap MF_01926 Phosphoribosylformylglycinamidine synthase subunit PurS [purS]. 2 76 18.981 T 06-07-2017 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 BWK49_RS03930 86cd2ca47275af94176deb068d0a62f4 79 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 4 74 8.8E-24 T 06-07-2017 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 BWK49_RS18455 a4fab66f1163d807291a1af566e98fd7 104 Gene3D G3DSA:1.10.8.50 50 100 1.0E-6 T 06-07-2017 BWK49_RS18455 a4fab66f1163d807291a1af566e98fd7 104 SUPERFAMILY SSF46946 54 102 3.41E-5 T 06-07-2017 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 BWK49_RS23200 2248134ada9e119ac4d9809e84276d29 139 SUPERFAMILY SSF82649 2 136 1.94E-28 T 06-07-2017 BWK49_RS23200 2248134ada9e119ac4d9809e84276d29 139 Gene3D G3DSA:3.90.1010.10 1 137 1.5E-33 T 06-07-2017 BWK49_RS23200 2248134ada9e119ac4d9809e84276d29 139 Pfam PF02657 Fe-S metabolism associated domain 12 133 1.2E-28 T 06-07-2017 IPR003808 Fe-S metabolism associated domain, SufE-like BWK49_RS14900 7351c67dd28d80a2d4e25967c580631a 802 Gene3D G3DSA:3.40.50.10540 703 795 9.7E-75 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS14900 7351c67dd28d80a2d4e25967c580631a 802 Gene3D G3DSA:3.40.50.10540 395 615 9.7E-75 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS14900 7351c67dd28d80a2d4e25967c580631a 802 Gene3D G3DSA:3.40.50.10540 308 378 3.5E-61 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS14900 7351c67dd28d80a2d4e25967c580631a 802 Gene3D G3DSA:3.40.50.10540 5 216 3.5E-61 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS14900 7351c67dd28d80a2d4e25967c580631a 802 Pfam PF02515 CoA-transferase family III 398 771 7.6E-96 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 BWK49_RS14900 7351c67dd28d80a2d4e25967c580631a 802 Pfam PF02515 CoA-transferase family III 8 374 3.9E-68 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 BWK49_RS14900 7351c67dd28d80a2d4e25967c580631a 802 SUPERFAMILY SSF89796 396 794 1.23E-91 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS14900 7351c67dd28d80a2d4e25967c580631a 802 SUPERFAMILY SSF89796 3 375 3.53E-75 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS14900 7351c67dd28d80a2d4e25967c580631a 802 Gene3D G3DSA:3.30.1540.10 630 702 7.4E-26 T 06-07-2017 BWK49_RS14900 7351c67dd28d80a2d4e25967c580631a 802 Gene3D G3DSA:3.30.1540.10 226 307 6.7E-19 T 06-07-2017 BWK49_RS11255 436fb75c56f9ffc74e7ddcfc318646f9 410 Pfam PF00872 Transposase, Mutator family 24 379 1.4E-116 T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 BWK49_RS11255 436fb75c56f9ffc74e7ddcfc318646f9 410 ProSitePatterns PS01007 Transposases, Mutator family, signature. 238 262 - T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 BWK49_RS00410 436fb75c56f9ffc74e7ddcfc318646f9 410 Pfam PF00872 Transposase, Mutator family 24 379 1.4E-116 T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 BWK49_RS00410 436fb75c56f9ffc74e7ddcfc318646f9 410 ProSitePatterns PS01007 Transposases, Mutator family, signature. 238 262 - T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 BWK49_RS20440 436fb75c56f9ffc74e7ddcfc318646f9 410 Pfam PF00872 Transposase, Mutator family 24 379 1.4E-116 T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 BWK49_RS20440 436fb75c56f9ffc74e7ddcfc318646f9 410 ProSitePatterns PS01007 Transposases, Mutator family, signature. 238 262 - T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 BWK49_RS00560 212a189353fc14215cd83ece48ca1fe6 143 TIGRFAM TIGR02246 TIGR02246: conserved hypothetical protein 9 132 2.3E-38 T 06-07-2017 IPR011944 Steroid delta5-4-isomerase KEGG: 00140+5.3.3.1|KEGG: 00984+5.3.3.1|MetaCyc: PWY-2582|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-699|MetaCyc: PWY-7299 BWK49_RS00560 212a189353fc14215cd83ece48ca1fe6 143 SUPERFAMILY SSF54427 8 134 8.39E-35 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS00560 212a189353fc14215cd83ece48ca1fe6 143 Gene3D G3DSA:3.10.450.50 3 136 1.8E-42 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS00560 212a189353fc14215cd83ece48ca1fe6 143 Pfam PF14534 Domain of unknown function (DUF4440) 16 121 8.0E-10 T 06-07-2017 IPR027843 Domain of unknown function DUF4440 BWK49_RS26645 56b8c483cf3f4b9aa290372e1bc461a7 146 SUPERFAMILY SSF49764 15 131 1.57E-29 T 06-07-2017 IPR008978 HSP20-like chaperone BWK49_RS26645 56b8c483cf3f4b9aa290372e1bc461a7 146 Gene3D G3DSA:2.60.40.790 10 144 3.3E-31 T 06-07-2017 IPR008978 HSP20-like chaperone BWK49_RS26645 56b8c483cf3f4b9aa290372e1bc461a7 146 Pfam PF00011 Hsp20/alpha crystallin family 44 144 9.4E-18 T 06-07-2017 IPR002068 Alpha crystallin/Hsp20 domain BWK49_RS12150 45226277c315c42d8584e7e68e33671f 190 SUPERFAMILY SSF48498 73 185 4.45E-15 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS12150 45226277c315c42d8584e7e68e33671f 190 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 58 3.3E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS12150 45226277c315c42d8584e7e68e33671f 190 Gene3D G3DSA:1.10.357.10 6 186 7.1E-32 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS12150 45226277c315c42d8584e7e68e33671f 190 ProSitePatterns PS01081 TetR-type HTH domain signature. 29 60 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site BWK49_RS12150 45226277c315c42d8584e7e68e33671f 190 SUPERFAMILY SSF46689 6 70 5.82E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS12150 45226277c315c42d8584e7e68e33671f 190 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 75 162 1.9E-6 T 06-07-2017 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 BWK49_RS24810 7adcf5daff57df24e75dac9d5a5dd612 163 SUPERFAMILY SSF89963 5 89 2.09E-26 T 06-07-2017 IPR007551 Protein of unknown function DUF520 BWK49_RS24810 7adcf5daff57df24e75dac9d5a5dd612 163 Pfam PF04461 Protein of unknown function (DUF520) 4 163 2.7E-61 T 06-07-2017 IPR007551 Protein of unknown function DUF520 BWK49_RS24810 7adcf5daff57df24e75dac9d5a5dd612 163 Gene3D G3DSA:3.30.70.860 98 163 6.5E-31 T 06-07-2017 BWK49_RS24810 7adcf5daff57df24e75dac9d5a5dd612 163 Gene3D G3DSA:3.30.70.990 11 97 1.7E-30 T 06-07-2017 BWK49_RS24810 7adcf5daff57df24e75dac9d5a5dd612 163 Hamap MF_00632 UPF0234 protein YajQ [yajQ]. 3 163 26.59 T 06-07-2017 IPR007551 Protein of unknown function DUF520 BWK49_RS24810 7adcf5daff57df24e75dac9d5a5dd612 163 SUPERFAMILY SSF89963 91 163 1.18E-24 T 06-07-2017 IPR007551 Protein of unknown function DUF520 BWK49_RS16050 a322a288e484f36c8450400ef3689d98 781 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 233 739 2.1E-95 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 BWK49_RS16050 a322a288e484f36c8450400ef3689d98 781 SUPERFAMILY SSF81665 361 452 1.83E-10 T 06-07-2017 BWK49_RS16050 a322a288e484f36c8450400ef3689d98 781 SUPERFAMILY SSF81665 229 264 1.83E-10 T 06-07-2017 BWK49_RS16050 a322a288e484f36c8450400ef3689d98 781 Gene3D G3DSA:3.40.1110.10 475 587 3.0E-28 T 06-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 BWK49_RS16050 a322a288e484f36c8450400ef3689d98 781 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 660 679 1.1E-30 T 06-07-2017 BWK49_RS16050 a322a288e484f36c8450400ef3689d98 781 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 585 596 1.1E-30 T 06-07-2017 BWK49_RS16050 a322a288e484f36c8450400ef3689d98 781 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 310 324 1.1E-30 T 06-07-2017 BWK49_RS16050 a322a288e484f36c8450400ef3689d98 781 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 683 695 1.1E-30 T 06-07-2017 BWK49_RS16050 a322a288e484f36c8450400ef3689d98 781 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 460 474 1.1E-30 T 06-07-2017 BWK49_RS16050 a322a288e484f36c8450400ef3689d98 781 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 607 617 1.1E-30 T 06-07-2017 BWK49_RS16050 a322a288e484f36c8450400ef3689d98 781 SUPERFAMILY SSF56784 458 478 1.87E-65 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS16050 a322a288e484f36c8450400ef3689d98 781 SUPERFAMILY SSF56784 517 760 1.87E-65 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS16050 a322a288e484f36c8450400ef3689d98 781 Pfam PF00702 haloacid dehalogenase-like hydrolase 456 674 5.1E-54 T 06-07-2017 BWK49_RS16050 a322a288e484f36c8450400ef3689d98 781 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 691 716 5.6E-8 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 BWK49_RS16050 a322a288e484f36c8450400ef3689d98 781 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 660 676 5.6E-8 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 BWK49_RS16050 a322a288e484f36c8450400ef3689d98 781 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 181 763 6.4E-182 T 06-07-2017 BWK49_RS16050 a322a288e484f36c8450400ef3689d98 781 Gene3D G3DSA:3.40.50.1000 588 728 9.4E-60 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS16050 a322a288e484f36c8450400ef3689d98 781 Gene3D G3DSA:3.40.50.1000 431 474 9.4E-60 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS16050 a322a288e484f36c8450400ef3689d98 781 Pfam PF00122 E1-E2 ATPase 231 451 1.4E-68 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 BWK49_RS16050 a322a288e484f36c8450400ef3689d98 781 SUPERFAMILY SSF81653 265 360 3.66E-30 T 06-07-2017 BWK49_RS16050 a322a288e484f36c8450400ef3689d98 781 Gene3D G3DSA:2.70.150.10 198 361 3.5E-36 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 BWK49_RS16050 a322a288e484f36c8450400ef3689d98 781 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 200 762 3.1E-198 T 06-07-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 BWK49_RS16050 a322a288e484f36c8450400ef3689d98 781 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 462 468 - T 06-07-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 BWK49_RS09870 0396afc5bfa25ed4b16af79dccbfb03c 857 Pfam PF11838 ERAP1-like C-terminal domain 528 847 1.0E-56 T 06-07-2017 IPR024571 ERAP1-like C-terminal domain BWK49_RS09870 0396afc5bfa25ed4b16af79dccbfb03c 857 TIGRFAM TIGR02412 pepN_strep_liv: aminopeptidase N 5 853 2.8E-303 T 06-07-2017 IPR012778 Peptidase M1, aminopeptidase GO:0004177|GO:0006508 KEGG: 00480+3.4.11.2|MetaCyc: PWY-4061|MetaCyc: PWY-6842|MetaCyc: PWY-7112 BWK49_RS09870 0396afc5bfa25ed4b16af79dccbfb03c 857 Pfam PF01433 Peptidase family M1 102 388 7.4E-73 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 BWK49_RS09870 0396afc5bfa25ed4b16af79dccbfb03c 857 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 296 311 2.2E-25 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 BWK49_RS09870 0396afc5bfa25ed4b16af79dccbfb03c 857 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 136 151 2.2E-25 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 BWK49_RS09870 0396afc5bfa25ed4b16af79dccbfb03c 857 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 262 272 2.2E-25 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 BWK49_RS09870 0396afc5bfa25ed4b16af79dccbfb03c 857 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 315 327 2.2E-25 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 BWK49_RS09870 0396afc5bfa25ed4b16af79dccbfb03c 857 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 179 194 2.2E-25 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 BWK49_RS09870 0396afc5bfa25ed4b16af79dccbfb03c 857 SUPERFAMILY SSF63737 6 196 2.48E-42 T 06-07-2017 BWK49_RS09870 0396afc5bfa25ed4b16af79dccbfb03c 857 SUPERFAMILY SSF55486 207 455 1.61E-77 T 06-07-2017 BWK49_RS09870 0396afc5bfa25ed4b16af79dccbfb03c 857 Gene3D G3DSA:1.10.390.10 309 456 1.1E-43 T 06-07-2017 BWK49_RS16665 344aafe01d3f21be0eb51352a06e7cfb 269 Pfam PF01728 FtsJ-like methyltransferase 62 242 1.1E-23 T 06-07-2017 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 BWK49_RS16665 344aafe01d3f21be0eb51352a06e7cfb 269 TIGRFAM TIGR00478 tly: TlyA family rRNA methyltransferase/putative hemolysin 6 238 3.3E-65 T 06-07-2017 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 BWK49_RS16665 344aafe01d3f21be0eb51352a06e7cfb 269 Gene3D G3DSA:3.40.50.150 92 178 3.0E-7 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS16665 344aafe01d3f21be0eb51352a06e7cfb 269 SUPERFAMILY SSF53335 61 243 7.2E-25 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS16665 344aafe01d3f21be0eb51352a06e7cfb 269 Pfam PF01479 S4 domain 6 46 9.5E-8 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 BWK49_RS16665 344aafe01d3f21be0eb51352a06e7cfb 269 PIRSF PIRSF005578 1 264 3.1E-95 T 06-07-2017 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 BWK49_RS16665 344aafe01d3f21be0eb51352a06e7cfb 269 SMART SM00363 5 71 3.6E-7 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 BWK49_RS16665 344aafe01d3f21be0eb51352a06e7cfb 269 Gene3D G3DSA:3.10.290.10 6 91 1.4E-19 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 BWK49_RS16665 344aafe01d3f21be0eb51352a06e7cfb 269 SUPERFAMILY SSF55174 4 60 1.62E-10 T 06-07-2017 BWK49_RS27995 faadb4feca52d122fbf56139410004a9 518 Gene3D G3DSA:3.50.50.60 301 502 2.9E-18 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS27995 faadb4feca52d122fbf56139410004a9 518 Gene3D G3DSA:3.50.50.60 24 234 8.0E-60 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS27995 faadb4feca52d122fbf56139410004a9 518 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 27 46 2.6E-5 T 06-07-2017 BWK49_RS27995 faadb4feca52d122fbf56139410004a9 518 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 195 213 2.6E-5 T 06-07-2017 BWK49_RS27995 faadb4feca52d122fbf56139410004a9 518 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 29 237 2.4E-18 T 06-07-2017 BWK49_RS27995 faadb4feca52d122fbf56139410004a9 518 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 195 220 7.1E-6 T 06-07-2017 BWK49_RS27995 faadb4feca52d122fbf56139410004a9 518 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 26 48 7.1E-6 T 06-07-2017 BWK49_RS27995 faadb4feca52d122fbf56139410004a9 518 SUPERFAMILY SSF51905 315 433 5.89E-54 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS27995 faadb4feca52d122fbf56139410004a9 518 SUPERFAMILY SSF51905 25 249 5.89E-54 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS18725 666f686489cb86de5d7de96ce64834e3 147 PIRSF PIRSF021591 1 147 5.7E-51 T 06-07-2017 IPR016793 Uncharacterised conserved protein UCP021591 BWK49_RS08410 f8f74470d6bc0b66b360ac4a5b61f754 486 Gene3D G3DSA:3.40.605.10 10 268 3.2E-76 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 BWK49_RS08410 f8f74470d6bc0b66b360ac4a5b61f754 486 Gene3D G3DSA:3.40.309.10 269 448 7.5E-60 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 BWK49_RS08410 f8f74470d6bc0b66b360ac4a5b61f754 486 SUPERFAMILY SSF53720 7 480 9.29E-145 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 BWK49_RS08410 f8f74470d6bc0b66b360ac4a5b61f754 486 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 255 262 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 BWK49_RS08410 f8f74470d6bc0b66b360ac4a5b61f754 486 Pfam PF00171 Aldehyde dehydrogenase family 19 480 1.5E-148 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 BWK49_RS11610 865e68bfb0ac1d68b36b9a385de7c2f2 162 SUPERFAMILY SSF46785 24 147 3.54E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS11610 865e68bfb0ac1d68b36b9a385de7c2f2 162 Gene3D G3DSA:1.10.10.10 13 148 4.8E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS11610 865e68bfb0ac1d68b36b9a385de7c2f2 162 Pfam PF01047 MarR family 40 97 2.5E-15 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 BWK49_RS11610 865e68bfb0ac1d68b36b9a385de7c2f2 162 SMART SM00347 34 132 7.4E-12 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 BWK49_RS14125 7526938dad6b4014c10ecd3479bd5d4c 236 SMART SM01110 32 236 5.4E-91 T 06-07-2017 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 BWK49_RS14125 7526938dad6b4014c10ecd3479bd5d4c 236 Pfam PF01083 Cutinase 33 236 6.3E-45 T 06-07-2017 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 BWK49_RS14125 7526938dad6b4014c10ecd3479bd5d4c 236 SUPERFAMILY SSF53474 25 235 6.87E-39 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS14125 7526938dad6b4014c10ecd3479bd5d4c 236 Gene3D G3DSA:3.40.50.1820 24 236 1.7E-52 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS28890 ef91e09b973bd64331327385fcf95237 97 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 4 92 2.2E-24 T 06-07-2017 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family BWK49_RS28890 ef91e09b973bd64331327385fcf95237 97 PIRSF PIRSF029218 1 97 6.8E-35 T 06-07-2017 IPR028344 Toxin-antitoxin system, toxin component ParE1/4 BWK49_RS26920 09d1a9e4504bcc17c9d56eb1b2cf9021 388 Pfam PF00534 Glycosyl transferases group 1 200 352 6.6E-31 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 BWK49_RS26920 09d1a9e4504bcc17c9d56eb1b2cf9021 388 SUPERFAMILY SSF53756 7 373 4.19E-68 T 06-07-2017 BWK49_RS26920 09d1a9e4504bcc17c9d56eb1b2cf9021 388 Pfam PF13439 Glycosyltransferase Family 4 21 186 1.5E-15 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 BWK49_RS26920 09d1a9e4504bcc17c9d56eb1b2cf9021 388 Gene3D G3DSA:3.40.50.2000 196 352 1.6E-27 T 06-07-2017 BWK49_RS20360 338a449f5f008406d342ee5e132638fa 820 Gene3D G3DSA:3.30.460.10 38 100 5.8E-5 T 06-07-2017 BWK49_RS20360 338a449f5f008406d342ee5e132638fa 820 Gene3D G3DSA:3.30.70.260 623 666 6.1E-4 T 06-07-2017 BWK49_RS20360 338a449f5f008406d342ee5e132638fa 820 Gene3D G3DSA:3.30.70.260 739 802 3.4E-7 T 06-07-2017 BWK49_RS20360 338a449f5f008406d342ee5e132638fa 820 Pfam PF01966 HD domain 442 535 1.8E-10 T 06-07-2017 IPR006674 HD domain BWK49_RS20360 338a449f5f008406d342ee5e132638fa 820 Gene3D G3DSA:1.10.3210.10 413 584 5.8E-22 T 06-07-2017 IPR006674 HD domain BWK49_RS20360 338a449f5f008406d342ee5e132638fa 820 Hamap MF_00277 Bifunctional uridylyltransferase/uridylyl-removing enzyme [glnD]. 1 820 66.545 T 06-07-2017 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 BWK49_RS20360 338a449f5f008406d342ee5e132638fa 820 SUPERFAMILY SSF81301 39 166 7.09E-16 T 06-07-2017 BWK49_RS20360 338a449f5f008406d342ee5e132638fa 820 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 44 101 1.0E-4 T 06-07-2017 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 BWK49_RS20360 338a449f5f008406d342ee5e132638fa 820 SMART SM00471 437 570 8.0E-9 T 06-07-2017 IPR003607 HD/PDEase domain BWK49_RS20360 338a449f5f008406d342ee5e132638fa 820 TIGRFAM TIGR01693 UTase_glnD: protein-P-II uridylyltransferase 32 598 4.7E-186 T 06-07-2017 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 BWK49_RS20360 338a449f5f008406d342ee5e132638fa 820 SUPERFAMILY SSF109604 408 515 3.45E-15 T 06-07-2017 BWK49_RS20360 338a449f5f008406d342ee5e132638fa 820 SUPERFAMILY SSF55021 739 814 3.87E-8 T 06-07-2017 BWK49_RS20360 338a449f5f008406d342ee5e132638fa 820 Pfam PF08335 GlnD PII-uridylyltransferase 181 298 3.9E-5 T 06-07-2017 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 BWK49_RS15400 7918f2790901f7bac9ac3a4ab798950e 450 SUPERFAMILY SSF55961 154 412 1.02E-32 T 06-07-2017 BWK49_RS15400 7918f2790901f7bac9ac3a4ab798950e 450 ProSitePatterns PS00570 Bacterial ring hydroxylating dioxygenases alpha-subunit signature. 81 103 - T 06-07-2017 IPR015881 Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site GO:0005506|GO:0016705|GO:0051537|GO:0055114 BWK49_RS15400 7918f2790901f7bac9ac3a4ab798950e 450 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 94 114 2.8E-13 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS15400 7918f2790901f7bac9ac3a4ab798950e 450 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 23 48 2.8E-13 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS15400 7918f2790901f7bac9ac3a4ab798950e 450 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 53 68 2.8E-13 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS15400 7918f2790901f7bac9ac3a4ab798950e 450 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 137 163 2.8E-13 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS15400 7918f2790901f7bac9ac3a4ab798950e 450 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 174 196 2.8E-13 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS15400 7918f2790901f7bac9ac3a4ab798950e 450 Gene3D G3DSA:2.102.10.10 39 144 4.1E-24 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS15400 7918f2790901f7bac9ac3a4ab798950e 450 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 174 414 4.7E-21 T 06-07-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 BWK49_RS15400 7918f2790901f7bac9ac3a4ab798950e 450 Pfam PF00355 Rieske [2Fe-2S] domain 39 112 3.2E-17 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS15400 7918f2790901f7bac9ac3a4ab798950e 450 Gene3D G3DSA:3.90.380.10 145 343 4.8E-19 T 06-07-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 BWK49_RS15400 7918f2790901f7bac9ac3a4ab798950e 450 SUPERFAMILY SSF50022 6 153 4.98E-44 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS11075 7932fc4d5d59c39efada4dc556b13c53 288 Gene3D G3DSA:3.40.50.720 3 243 2.6E-62 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS11075 7932fc4d5d59c39efada4dc556b13c53 288 SUPERFAMILY SSF51735 4 245 3.17E-62 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS11075 7932fc4d5d59c39efada4dc556b13c53 288 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 154 2.4E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS11075 7932fc4d5d59c39efada4dc556b13c53 288 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 93 104 2.4E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS11075 7932fc4d5d59c39efada4dc556b13c53 288 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 166 185 2.4E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS11075 7932fc4d5d59c39efada4dc556b13c53 288 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 153 181 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS11075 7932fc4d5d59c39efada4dc556b13c53 288 Pfam PF00106 short chain dehydrogenase 9 205 9.8E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS11075 7932fc4d5d59c39efada4dc556b13c53 288 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 200 1.8E-4 T 06-07-2017 BWK49_RS11075 7932fc4d5d59c39efada4dc556b13c53 288 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 187 204 4.8E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS11075 7932fc4d5d59c39efada4dc556b13c53 288 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 4.8E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS11075 7932fc4d5d59c39efada4dc556b13c53 288 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 185 4.8E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS11075 7932fc4d5d59c39efada4dc556b13c53 288 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 93 104 4.8E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS11075 7932fc4d5d59c39efada4dc556b13c53 288 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 156 4.8E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS11075 7932fc4d5d59c39efada4dc556b13c53 288 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 4.8E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS22420 de7d9d4b56ccaae5d3dab297175ef9df 211 SUPERFAMILY SSF48498 89 198 1.22E-27 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS22420 de7d9d4b56ccaae5d3dab297175ef9df 211 Gene3D G3DSA:1.10.357.10 76 198 5.8E-36 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS22420 de7d9d4b56ccaae5d3dab297175ef9df 211 Gene3D G3DSA:1.10.10.60 10 69 6.2E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS22420 de7d9d4b56ccaae5d3dab297175ef9df 211 SUPERFAMILY SSF46689 11 75 5.64E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS22420 de7d9d4b56ccaae5d3dab297175ef9df 211 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 69 3.9E-12 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS00495 2f1e05a524aa1d359c6697436da625aa 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 184 2.9E-15 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS00495 2f1e05a524aa1d359c6697436da625aa 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 89 100 2.9E-15 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS00495 2f1e05a524aa1d359c6697436da625aa 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 2.9E-15 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS00495 2f1e05a524aa1d359c6697436da625aa 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 156 2.9E-15 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS00495 2f1e05a524aa1d359c6697436da625aa 287 Pfam PF00106 short chain dehydrogenase 7 205 9.3E-31 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS00495 2f1e05a524aa1d359c6697436da625aa 287 Gene3D G3DSA:3.40.50.720 4 248 3.2E-45 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS00495 2f1e05a524aa1d359c6697436da625aa 287 SUPERFAMILY SSF51735 5 237 1.22E-42 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS25235 2c56f1f5c5e80989bf8842c3b6953c9a 146 Gene3D G3DSA:3.30.750.24 30 123 1.6E-12 T 06-07-2017 IPR002645 STAS domain BWK49_RS25235 2c56f1f5c5e80989bf8842c3b6953c9a 146 SUPERFAMILY SSF52091 28 125 2.75E-12 T 06-07-2017 IPR002645 STAS domain BWK49_RS25235 2c56f1f5c5e80989bf8842c3b6953c9a 146 Pfam PF01740 STAS domain 30 123 8.4E-10 T 06-07-2017 IPR002645 STAS domain BWK49_RS15645 416473cf38cbecd60cdf47e27a40b733 508 Gene3D G3DSA:3.40.50.980 11 159 4.1E-19 T 06-07-2017 BWK49_RS15645 416473cf38cbecd60cdf47e27a40b733 508 Gene3D G3DSA:2.30.38.10 316 401 9.5E-19 T 06-07-2017 BWK49_RS15645 416473cf38cbecd60cdf47e27a40b733 508 Gene3D G3DSA:3.30.300.30 403 457 2.3E-8 T 06-07-2017 BWK49_RS15645 416473cf38cbecd60cdf47e27a40b733 508 Pfam PF00501 AMP-binding enzyme 12 407 8.2E-55 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS15645 416473cf38cbecd60cdf47e27a40b733 508 SUPERFAMILY SSF56801 11 456 4.84E-86 T 06-07-2017 BWK49_RS15645 416473cf38cbecd60cdf47e27a40b733 508 ProSitePatterns PS00455 Putative AMP-binding domain signature. 155 166 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS15645 416473cf38cbecd60cdf47e27a40b733 508 Gene3D G3DSA:3.40.50.980 160 315 6.5E-26 T 06-07-2017 BWK49_RS22170 c3c4ec3e7a22511dfc2c87c6b1ddfb68 254 SUPERFAMILY SSF56219 1 253 1.09E-29 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase BWK49_RS22170 c3c4ec3e7a22511dfc2c87c6b1ddfb68 254 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 4 244 8.8E-18 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase BWK49_RS22170 c3c4ec3e7a22511dfc2c87c6b1ddfb68 254 Gene3D G3DSA:3.60.10.10 1 201 1.5E-12 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase BWK49_RS27920 6b9447a429e586ba4ebd8675b06855de 181 Pfam PF11706 CGNR zinc finger 124 167 1.2E-12 T 06-07-2017 IPR021005 Zinc finger, CGNR BWK49_RS27920 6b9447a429e586ba4ebd8675b06855de 181 SUPERFAMILY SSF160904 1 166 6.28E-26 T 06-07-2017 BWK49_RS27920 6b9447a429e586ba4ebd8675b06855de 181 Pfam PF07336 Putative stress-induced transcription regulator 2 106 1.2E-7 T 06-07-2017 IPR010852 Putative stress-induced transcription regulator BWK49_RS27920 6b9447a429e586ba4ebd8675b06855de 181 Gene3D G3DSA:1.10.3300.10 1 169 5.6E-29 T 06-07-2017 IPR023286 ABATE domain BWK49_RS17340 5784ae1694c6f8208633f9b7d8530da0 137 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 35 127 3.7E-19 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 BWK49_RS17340 5784ae1694c6f8208633f9b7d8530da0 137 Pfam PF04075 Domain of unknown function (DUF385) 32 96 2.7E-4 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 BWK49_RS20370 0ffb319982e4b02daa31074a7f7a9baf 473 ProSitePatterns PS01219 Ammonium transporters signature. 186 211 - T 06-07-2017 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 BWK49_RS20370 0ffb319982e4b02daa31074a7f7a9baf 473 Gene3D G3DSA:1.10.3430.10 5 417 2.3E-132 T 06-07-2017 IPR029020 Ammonium/urea transporter BWK49_RS20370 0ffb319982e4b02daa31074a7f7a9baf 473 SUPERFAMILY SSF111352 6 417 6.54E-118 T 06-07-2017 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 BWK49_RS20370 0ffb319982e4b02daa31074a7f7a9baf 473 Pfam PF00909 Ammonium Transporter Family 12 436 4.4E-135 T 06-07-2017 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 BWK49_RS20370 0ffb319982e4b02daa31074a7f7a9baf 473 TIGRFAM TIGR00836 amt: ammonium transporter 9 436 2.1E-145 T 06-07-2017 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 BWK49_RS19940 3d1afb5ca15c0adfc331384033298e5f 148 SUPERFAMILY SSF47240 5 144 2.27E-43 T 06-07-2017 IPR009078 Ferritin-like superfamily BWK49_RS19940 3d1afb5ca15c0adfc331384033298e5f 148 Gene3D G3DSA:1.20.1260.10 5 137 1.3E-47 T 06-07-2017 IPR012347 Ferritin-related BWK49_RS19940 3d1afb5ca15c0adfc331384033298e5f 148 Pfam PF14530 Domain of unknown function (DUF4439) 11 146 5.8E-40 T 06-07-2017 IPR029447 Domain of unknown function DUF4439 BWK49_RS22185 eff16037d0abc429c07f50b4df770410 267 Gene3D G3DSA:3.40.50.720 6 199 6.5E-16 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS22185 eff16037d0abc429c07f50b4df770410 267 SUPERFAMILY SSF51735 5 189 3.54E-19 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS22185 eff16037d0abc429c07f50b4df770410 267 Pfam PF13460 NAD(P)H-binding 11 179 1.6E-6 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS01305 ba8aab0bb1941e19d8e3d07f289e68a7 368 Gene3D G3DSA:3.30.1330.30 258 299 3.0E-4 T 06-07-2017 IPR029064 50S ribosomal protein L30e-like BWK49_RS24355 0aa8e6d378a1be59c5e399e66bf9c424 243 TIGRFAM TIGR03964 mycofact_creat: mycofactocin system creatininase family protein 15 242 7.9E-111 T 06-07-2017 IPR023871 Mycofactocin system creatininase family protein BWK49_RS24355 0aa8e6d378a1be59c5e399e66bf9c424 243 Pfam PF02633 Creatinine amidohydrolase 25 229 3.5E-59 T 06-07-2017 IPR003785 Creatininase/formamide hydrolase KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167 BWK49_RS24355 0aa8e6d378a1be59c5e399e66bf9c424 243 SUPERFAMILY SSF102215 23 233 3.53E-59 T 06-07-2017 IPR024087 Creatininase-like domain KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167 BWK49_RS24355 0aa8e6d378a1be59c5e399e66bf9c424 243 Gene3D G3DSA:3.40.50.10310 28 234 4.2E-61 T 06-07-2017 IPR024087 Creatininase-like domain KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167 BWK49_RS15200 7ed3fe512a4c48b794a45963b5ff20a2 417 Pfam PF00823 PPE family 6 162 5.3E-62 T 06-07-2017 IPR000030 PPE family BWK49_RS15200 7ed3fe512a4c48b794a45963b5ff20a2 417 SUPERFAMILY SSF140459 3 175 4.18E-64 T 06-07-2017 BWK49_RS15200 7ed3fe512a4c48b794a45963b5ff20a2 417 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 316 387 1.0E-6 T 06-07-2017 IPR022171 PPE family, C-terminal BWK49_RS09320 29b5a41b5cb26b09f92bfe3eeb16b81e 410 Pfam PF04909 Amidohydrolase 101 390 5.5E-26 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 BWK49_RS09320 29b5a41b5cb26b09f92bfe3eeb16b81e 410 Gene3D G3DSA:3.20.20.140 76 393 2.5E-54 T 06-07-2017 BWK49_RS09320 29b5a41b5cb26b09f92bfe3eeb16b81e 410 Gene3D G3DSA:3.20.20.140 9 36 2.5E-54 T 06-07-2017 BWK49_RS09320 29b5a41b5cb26b09f92bfe3eeb16b81e 410 SUPERFAMILY SSF51556 8 36 6.88E-65 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS09320 29b5a41b5cb26b09f92bfe3eeb16b81e 410 SUPERFAMILY SSF51556 91 391 6.88E-65 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS07910 28d955e131aba4c8587c0b63ac0f1399 183 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 136 1.2E-7 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain BWK49_RS07910 28d955e131aba4c8587c0b63ac0f1399 183 SUPERFAMILY SSF54593 1 145 7.52E-18 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS07910 28d955e131aba4c8587c0b63ac0f1399 183 Gene3D G3DSA:3.10.180.10 1 137 6.7E-26 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS21645 5173e47bf34234336ec32c9c3c91bef0 424 SMART SM00507 314 364 1.8E-5 T 06-07-2017 IPR003615 HNH nuclease BWK49_RS21645 5173e47bf34234336ec32c9c3c91bef0 424 Pfam PF01844 HNH endonuclease 330 366 1.9E-5 T 06-07-2017 IPR002711 HNH endonuclease GO:0003676|GO:0004519 BWK49_RS21645 5173e47bf34234336ec32c9c3c91bef0 424 Pfam PF02720 Domain of unknown function (DUF222) 29 323 5.7E-13 T 06-07-2017 IPR003870 Domain of unknown function DUF222 BWK49_RS22140 e98e5524faffb13254d174532513ec64 344 SUPERFAMILY SSF52738 18 203 4.45E-51 T 06-07-2017 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 BWK49_RS22140 e98e5524faffb13254d174532513ec64 344 Gene3D G3DSA:3.40.50.180 20 203 1.8E-56 T 06-07-2017 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 BWK49_RS22140 e98e5524faffb13254d174532513ec64 344 PIRSF PIRSF036461 12 324 1.4E-80 T 06-07-2017 IPR011247 Chemotaxis protein-glutamate methylesterase BWK49_RS22140 e98e5524faffb13254d174532513ec64 344 Pfam PF01339 CheB methylesterase 22 195 2.4E-47 T 06-07-2017 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 BWK49_RS08655 340008f205b5658bf871d2517dc19fe8 193 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 1 190 1.0E-92 T 06-07-2017 BWK49_RS08655 340008f205b5658bf871d2517dc19fe8 193 Pfam PF14041 LppP/LprE lipoprotein 103 181 3.7E-14 T 06-07-2017 IPR025971 LppP/LprE lipoprotein BWK49_RS23055 527992d8e8007405b3913b6a585f7309 93 Pfam PF07371 Protein of unknown function (DUF1490) 1 87 5.3E-41 T 06-07-2017 IPR009963 Protein of unknown function DUF1490 BWK49_RS23055 527992d8e8007405b3913b6a585f7309 93 ProDom PD020015 MB2016C IRON REGULATED MB3297 RV1993C/MT2049 RV0968/MT0996 IRP10 ML0748 MB0993 1 84 5.0E-18 T 06-07-2017 IPR009963 Protein of unknown function DUF1490 BWK49_RS21995 881de86ab5971aa1167464f777d2d7dc 184 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 37 146 8.3E-25 T 06-07-2017 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS21995 881de86ab5971aa1167464f777d2d7dc 184 Gene3D G3DSA:3.40.50.700 24 149 3.1E-35 T 06-07-2017 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS21995 881de86ab5971aa1167464f777d2d7dc 184 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 11 152 8.5E-69 T 06-07-2017 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS21995 881de86ab5971aa1167464f777d2d7dc 184 ProSitePatterns PS01150 Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. 118 134 - T 06-07-2017 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS21995 881de86ab5971aa1167464f777d2d7dc 184 SUPERFAMILY SSF56770 9 152 3.27E-65 T 06-07-2017 BWK49_RS21995 881de86ab5971aa1167464f777d2d7dc 184 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 1 151 42.615 T 06-07-2017 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS02330 810fb96cd6e261e7a099bb91c3aa85f8 163 SUPERFAMILY SSF54593 7 143 4.56E-27 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS02330 810fb96cd6e261e7a099bb91c3aa85f8 163 Gene3D G3DSA:3.10.180.10 7 141 3.0E-26 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS02330 810fb96cd6e261e7a099bb91c3aa85f8 163 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 10 138 1.8E-15 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain BWK49_RS09340 f76011447b49c9321b1abfab3c6159e3 274 SUPERFAMILY SSF48264 1 271 1.7E-70 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS09340 f76011447b49c9321b1abfab3c6159e3 274 PRINTS PR00359 B-class P450 signature 164 191 2.5E-38 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS09340 f76011447b49c9321b1abfab3c6159e3 274 PRINTS PR00359 B-class P450 signature 192 207 2.5E-38 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS09340 f76011447b49c9321b1abfab3c6159e3 274 PRINTS PR00359 B-class P450 signature 213 222 2.5E-38 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS09340 f76011447b49c9321b1abfab3c6159e3 274 PRINTS PR00359 B-class P450 signature 147 158 2.5E-38 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS09340 f76011447b49c9321b1abfab3c6159e3 274 PRINTS PR00359 B-class P450 signature 29 44 2.5E-38 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS09340 f76011447b49c9321b1abfab3c6159e3 274 PRINTS PR00359 B-class P450 signature 12 28 2.5E-38 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS09340 f76011447b49c9321b1abfab3c6159e3 274 PRINTS PR00359 B-class P450 signature 66 88 2.5E-38 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS09340 f76011447b49c9321b1abfab3c6159e3 274 PRINTS PR00359 B-class P450 signature 222 233 2.5E-38 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS09340 f76011447b49c9321b1abfab3c6159e3 274 Pfam PF00067 Cytochrome P450 54 242 9.5E-24 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS09340 f76011447b49c9321b1abfab3c6159e3 274 Gene3D G3DSA:1.10.630.10 1 272 3.2E-84 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS21660 99b68c42d9431720dbf6a0fbd683ab76 188 Gene3D G3DSA:1.20.120.520 11 147 7.6E-8 T 06-07-2017 BWK49_RS21660 99b68c42d9431720dbf6a0fbd683ab76 188 Pfam PF01814 Hemerythrin HHE cation binding domain 13 129 2.1E-9 T 06-07-2017 IPR012312 Haemerythrin-like Reactome: R-HSA-390471 BWK49_RS10705 305d2ee14de05746e2afca119822e54b 427 Gene3D G3DSA:3.20.20.10 16 207 8.4E-42 T 06-07-2017 IPR029066 PLP-binding barrel BWK49_RS10705 305d2ee14de05746e2afca119822e54b 427 SUPERFAMILY SSF50621 270 406 7.33E-15 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 BWK49_RS10705 305d2ee14de05746e2afca119822e54b 427 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 32 220 3.0E-19 T 06-07-2017 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 BWK49_RS10705 305d2ee14de05746e2afca119822e54b 427 Gene3D G3DSA:2.40.37.10 208 219 7.1E-22 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 BWK49_RS10705 305d2ee14de05746e2afca119822e54b 427 Gene3D G3DSA:2.40.37.10 256 411 7.1E-22 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 BWK49_RS10705 305d2ee14de05746e2afca119822e54b 427 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 278 297 2.1E-7 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 BWK49_RS10705 305d2ee14de05746e2afca119822e54b 427 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 39 57 2.1E-7 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 BWK49_RS10705 305d2ee14de05746e2afca119822e54b 427 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 59 71 2.1E-7 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 BWK49_RS10705 305d2ee14de05746e2afca119822e54b 427 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 160 173 2.1E-7 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 BWK49_RS10705 305d2ee14de05746e2afca119822e54b 427 SUPERFAMILY SSF51419 243 291 7.36E-41 T 06-07-2017 IPR029066 PLP-binding barrel BWK49_RS10705 305d2ee14de05746e2afca119822e54b 427 SUPERFAMILY SSF51419 14 215 7.36E-41 T 06-07-2017 IPR029066 PLP-binding barrel BWK49_RS19515 7d0b234e6c04512abd68ecc8d63fdc13 236 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 152 162 1.6E-11 T 06-07-2017 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 BWK49_RS19515 7d0b234e6c04512abd68ecc8d63fdc13 236 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 163 174 1.6E-11 T 06-07-2017 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 BWK49_RS19515 7d0b234e6c04512abd68ecc8d63fdc13 236 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 191 203 1.6E-11 T 06-07-2017 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 BWK49_RS19515 7d0b234e6c04512abd68ecc8d63fdc13 236 Hamap MF_00015 LexA repressor [lexA]. 26 236 32.98 T 06-07-2017 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 BWK49_RS19515 7d0b234e6c04512abd68ecc8d63fdc13 236 TIGRFAM TIGR00498 lexA: repressor LexA 25 236 1.7E-83 T 06-07-2017 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 BWK49_RS19515 7d0b234e6c04512abd68ecc8d63fdc13 236 Gene3D G3DSA:2.10.109.10 117 235 1.1E-43 T 06-07-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain BWK49_RS19515 7d0b234e6c04512abd68ecc8d63fdc13 236 SUPERFAMILY SSF51306 115 234 2.09E-35 T 06-07-2017 IPR015927 Peptidase S24/S26A/S26B/S26C BWK49_RS19515 7d0b234e6c04512abd68ecc8d63fdc13 236 Pfam PF00717 Peptidase S24-like 155 222 1.1E-15 T 06-07-2017 IPR019759 Peptidase S24/S26A/S26B BWK49_RS19515 7d0b234e6c04512abd68ecc8d63fdc13 236 Pfam PF01726 LexA DNA binding domain 25 88 1.2E-29 T 06-07-2017 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 BWK49_RS19515 7d0b234e6c04512abd68ecc8d63fdc13 236 Gene3D G3DSA:1.10.10.10 26 92 1.6E-31 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS19515 7d0b234e6c04512abd68ecc8d63fdc13 236 SUPERFAMILY SSF46785 26 92 3.28E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS22365 2d03f56c3a084ec626e5d62363fee1c6 343 SUPERFAMILY SSF111331 3 318 3.49E-18 T 06-07-2017 IPR016064 NAD kinase/diacylglycerol kinase-like domain BWK49_RS22365 2d03f56c3a084ec626e5d62363fee1c6 343 Pfam PF00781 Diacylglycerol kinase catalytic domain 5 117 1.8E-6 T 06-07-2017 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 BWK49_RS14060 3684e50513f53028d4126551ef7902d8 299 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 1 262 1.4E-74 T 06-07-2017 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 BWK49_RS14060 3684e50513f53028d4126551ef7902d8 299 SUPERFAMILY SSF53335 1 265 1.58E-66 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS14060 3684e50513f53028d4126551ef7902d8 299 Pfam PF04072 Leucine carboxyl methyltransferase 1 181 1.9E-61 T 06-07-2017 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 BWK49_RS14060 3684e50513f53028d4126551ef7902d8 299 Gene3D G3DSA:3.40.50.150 61 196 1.0E-11 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS23460 4310c97f5463c8896882337a09bc6934 443 Gene3D G3DSA:3.40.640.10 55 315 2.8E-85 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 BWK49_RS23460 4310c97f5463c8896882337a09bc6934 443 SUPERFAMILY SSF53383 11 437 1.3E-123 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase BWK49_RS23460 4310c97f5463c8896882337a09bc6934 443 Gene3D G3DSA:3.90.1150.10 316 438 5.4E-31 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 BWK49_RS23460 4310c97f5463c8896882337a09bc6934 443 PIRSF PIRSF000521 21 439 7.0E-23 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 BWK49_RS23460 4310c97f5463c8896882337a09bc6934 443 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 242 279 - T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 BWK49_RS23460 4310c97f5463c8896882337a09bc6934 443 Pfam PF00202 Aminotransferase class-III 20 435 7.6E-102 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 BWK49_RS10685 f532a60e5a44f606c981c0e6d4a9e401 415 Gene3D G3DSA:1.20.1250.20 207 398 2.5E-10 T 06-07-2017 BWK49_RS10685 f532a60e5a44f606c981c0e6d4a9e401 415 Pfam PF07690 Major Facilitator Superfamily 23 301 1.2E-16 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 BWK49_RS10685 f532a60e5a44f606c981c0e6d4a9e401 415 SUPERFAMILY SSF103473 14 399 1.7E-38 T 06-07-2017 IPR020846 Major facilitator superfamily domain BWK49_RS10685 f532a60e5a44f606c981c0e6d4a9e401 415 Gene3D G3DSA:1.20.1250.20 20 190 9.6E-20 T 06-07-2017 BWK49_RS17860 48cad7e8ff400025ad1c964634a8eb22 340 ProSitePatterns PS00534 Ferrochelatase signature. 171 191 - T 06-07-2017 IPR019772 Ferrochelatase, active site GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 BWK49_RS17860 48cad7e8ff400025ad1c964634a8eb22 340 Hamap MF_00323 Ferrochelatase [hemH]. 2 303 31.691 T 06-07-2017 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 BWK49_RS17860 48cad7e8ff400025ad1c964634a8eb22 340 Pfam PF00762 Ferrochelatase 4 301 9.1E-96 T 06-07-2017 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 BWK49_RS17860 48cad7e8ff400025ad1c964634a8eb22 340 TIGRFAM TIGR00109 hemH: ferrochelatase 5 302 2.3E-39 T 06-07-2017 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 BWK49_RS17860 48cad7e8ff400025ad1c964634a8eb22 340 SUPERFAMILY SSF53800 2 321 8.99E-85 T 06-07-2017 BWK49_RS17860 48cad7e8ff400025ad1c964634a8eb22 340 Gene3D G3DSA:3.40.50.1400 155 282 2.2E-43 T 06-07-2017 BWK49_RS17860 48cad7e8ff400025ad1c964634a8eb22 340 Gene3D G3DSA:3.40.50.1400 2 154 5.3E-42 T 06-07-2017 BWK49_RS24305 b2cd53019ae4f3a3694775062c9abc9b 93 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 25.232 T 06-07-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 BWK49_RS24305 b2cd53019ae4f3a3694775062c9abc9b 93 Pfam PF00203 Ribosomal protein S19 3 83 4.1E-37 T 06-07-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 BWK49_RS24305 b2cd53019ae4f3a3694775062c9abc9b 93 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 3.2E-24 T 06-07-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 BWK49_RS24305 b2cd53019ae4f3a3694775062c9abc9b 93 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 3.2E-24 T 06-07-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 BWK49_RS24305 b2cd53019ae4f3a3694775062c9abc9b 93 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 3.2E-24 T 06-07-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 BWK49_RS24305 b2cd53019ae4f3a3694775062c9abc9b 93 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 06-07-2017 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 BWK49_RS24305 b2cd53019ae4f3a3694775062c9abc9b 93 PIRSF PIRSF002144 1 93 1.0E-31 T 06-07-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 BWK49_RS24305 b2cd53019ae4f3a3694775062c9abc9b 93 Gene3D G3DSA:3.30.860.10 1 92 5.7E-42 T 06-07-2017 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 BWK49_RS24305 b2cd53019ae4f3a3694775062c9abc9b 93 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 92 6.4E-48 T 06-07-2017 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 BWK49_RS24305 b2cd53019ae4f3a3694775062c9abc9b 93 SUPERFAMILY SSF54570 3 83 7.06E-35 T 06-07-2017 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 BWK49_RS19880 d0747e2b526f258da9cf57ecef2bd756 186 PIRSF PIRSF018957 1 186 1.3E-82 T 06-07-2017 IPR008307 Uncharacterised conserved protein UCP018957 BWK49_RS19880 d0747e2b526f258da9cf57ecef2bd756 186 Pfam PF08819 Domain of unknown function (DUF1802) 9 178 2.2E-57 T 06-07-2017 IPR014923 Protein of unknown function DUF1802 BWK49_RS00270 849d9afd122e272970e44166278e7a94 223 SUPERFAMILY SSF51735 3 216 4.93E-53 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS00270 849d9afd122e272970e44166278e7a94 223 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 126 154 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS00270 849d9afd122e272970e44166278e7a94 223 Gene3D G3DSA:3.40.50.720 3 209 2.4E-52 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS00270 849d9afd122e272970e44166278e7a94 223 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 158 8.5E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS00270 849d9afd122e272970e44166278e7a94 223 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 67 78 8.5E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS00270 849d9afd122e272970e44166278e7a94 223 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 119 127 8.5E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS00270 849d9afd122e272970e44166278e7a94 223 Pfam PF00106 short chain dehydrogenase 3 180 3.0E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS00270 849d9afd122e272970e44166278e7a94 223 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 5.6E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS00270 849d9afd122e272970e44166278e7a94 223 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 139 158 5.6E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS00270 849d9afd122e272970e44166278e7a94 223 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 113 129 5.6E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS00270 849d9afd122e272970e44166278e7a94 223 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 220 223 5.6E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS00270 849d9afd122e272970e44166278e7a94 223 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 67 78 5.6E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS00270 849d9afd122e272970e44166278e7a94 223 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 175 5.6E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27535 fa8f4c57a8dacf37877bf6237ce5a20b 441 PRINTS PR00463 E-class P450 group I signature 41 60 8.1E-28 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS27535 fa8f4c57a8dacf37877bf6237ce5a20b 441 PRINTS PR00463 E-class P450 group I signature 252 269 8.1E-28 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS27535 fa8f4c57a8dacf37877bf6237ce5a20b 441 PRINTS PR00463 E-class P450 group I signature 151 169 8.1E-28 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS27535 fa8f4c57a8dacf37877bf6237ce5a20b 441 PRINTS PR00463 E-class P450 group I signature 272 298 8.1E-28 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS27535 fa8f4c57a8dacf37877bf6237ce5a20b 441 PRINTS PR00463 E-class P450 group I signature 305 323 8.1E-28 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS27535 fa8f4c57a8dacf37877bf6237ce5a20b 441 PRINTS PR00463 E-class P450 group I signature 346 370 8.1E-28 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS27535 fa8f4c57a8dacf37877bf6237ce5a20b 441 PRINTS PR00463 E-class P450 group I signature 378 388 8.1E-28 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS27535 fa8f4c57a8dacf37877bf6237ce5a20b 441 PRINTS PR00463 E-class P450 group I signature 388 411 8.1E-28 T 06-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS27535 fa8f4c57a8dacf37877bf6237ce5a20b 441 Pfam PF00067 Cytochrome P450 35 414 6.4E-58 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS27535 fa8f4c57a8dacf37877bf6237ce5a20b 441 Gene3D G3DSA:1.10.630.10 31 441 1.7E-84 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS27535 fa8f4c57a8dacf37877bf6237ce5a20b 441 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 381 390 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 BWK49_RS27535 fa8f4c57a8dacf37877bf6237ce5a20b 441 PRINTS PR00385 P450 superfamily signature 388 399 1.0E-10 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS27535 fa8f4c57a8dacf37877bf6237ce5a20b 441 PRINTS PR00385 P450 superfamily signature 306 317 1.0E-10 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS27535 fa8f4c57a8dacf37877bf6237ce5a20b 441 PRINTS PR00385 P450 superfamily signature 263 280 1.0E-10 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS27535 fa8f4c57a8dacf37877bf6237ce5a20b 441 PRINTS PR00385 P450 superfamily signature 379 388 1.0E-10 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS27535 fa8f4c57a8dacf37877bf6237ce5a20b 441 SUPERFAMILY SSF48264 33 441 2.23E-81 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS21450 018dab2b65c147bb901ce894ae6a089c 381 Gene3D G3DSA:3.30.1540.10 221 288 3.2E-9 T 06-07-2017 BWK49_RS21450 018dab2b65c147bb901ce894ae6a089c 381 Pfam PF02515 CoA-transferase family III 5 350 2.8E-77 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 BWK49_RS21450 018dab2b65c147bb901ce894ae6a089c 381 Gene3D G3DSA:3.40.50.10540 2 205 2.4E-94 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS21450 018dab2b65c147bb901ce894ae6a089c 381 Gene3D G3DSA:3.40.50.10540 289 379 2.4E-94 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS21450 018dab2b65c147bb901ce894ae6a089c 381 SUPERFAMILY SSF89796 1 374 3.66E-108 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS01320 32f797d85569a2e4d9eabc75e556f174 274 Gene3D G3DSA:1.10.12.10 216 273 4.1E-22 T 06-07-2017 IPR014748 Crontonase, C-terminal BWK49_RS01320 32f797d85569a2e4d9eabc75e556f174 274 Pfam PF00378 Enoyl-CoA hydratase/isomerase 12 273 6.0E-41 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 BWK49_RS01320 32f797d85569a2e4d9eabc75e556f174 274 Gene3D G3DSA:3.90.226.10 4 215 9.2E-60 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS01320 32f797d85569a2e4d9eabc75e556f174 274 SUPERFAMILY SSF52096 4 273 1.76E-73 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS03760 7fdae706609bc52e3dfd1b49597b9e48 480 PRINTS PR00344 Bacterial sensor protein C-terminal signature 394 408 6.2E-19 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 BWK49_RS03760 7fdae706609bc52e3dfd1b49597b9e48 480 PRINTS PR00344 Bacterial sensor protein C-terminal signature 412 422 6.2E-19 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 BWK49_RS03760 7fdae706609bc52e3dfd1b49597b9e48 480 PRINTS PR00344 Bacterial sensor protein C-terminal signature 453 466 6.2E-19 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 BWK49_RS03760 7fdae706609bc52e3dfd1b49597b9e48 480 PRINTS PR00344 Bacterial sensor protein C-terminal signature 429 447 6.2E-19 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 BWK49_RS03760 7fdae706609bc52e3dfd1b49597b9e48 480 SUPERFAMILY SSF47384 238 311 2.94E-16 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 BWK49_RS03760 7fdae706609bc52e3dfd1b49597b9e48 480 SUPERFAMILY SSF158472 183 230 8.24E-8 T 06-07-2017 BWK49_RS03760 7fdae706609bc52e3dfd1b49597b9e48 480 Pfam PF00512 His Kinase A (phospho-acceptor) domain 249 310 7.0E-16 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 BWK49_RS03760 7fdae706609bc52e3dfd1b49597b9e48 480 Pfam PF00672 HAMP domain 161 229 1.6E-13 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 BWK49_RS03760 7fdae706609bc52e3dfd1b49597b9e48 480 SMART SM00304 180 233 1.7E-10 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 BWK49_RS03760 7fdae706609bc52e3dfd1b49597b9e48 480 SMART SM00387 357 469 1.1E-41 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS03760 7fdae706609bc52e3dfd1b49597b9e48 480 Gene3D G3DSA:3.30.565.10 298 468 6.8E-47 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS03760 7fdae706609bc52e3dfd1b49597b9e48 480 SUPERFAMILY SSF55874 301 467 1.83E-44 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS03760 7fdae706609bc52e3dfd1b49597b9e48 480 Gene3D G3DSA:1.10.287.130 239 297 1.3E-17 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 BWK49_RS03760 7fdae706609bc52e3dfd1b49597b9e48 480 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 357 466 1.2E-27 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS03760 7fdae706609bc52e3dfd1b49597b9e48 480 SMART SM00388 248 312 7.2E-17 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 BWK49_RS11460 5ffaa947ae8d45886c10c3b66970e75f 299 Hamap MF_00367 GTPase Era [era]. 4 299 34.833 T 06-07-2017 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 BWK49_RS11460 5ffaa947ae8d45886c10c3b66970e75f 299 Pfam PF01926 50S ribosome-binding GTPase 9 111 4.4E-20 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 BWK49_RS11460 5ffaa947ae8d45886c10c3b66970e75f 299 Gene3D G3DSA:3.40.50.300 5 174 1.0E-36 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS11460 5ffaa947ae8d45886c10c3b66970e75f 299 Gene3D G3DSA:3.30.300.20 189 294 1.1E-37 T 06-07-2017 IPR015946 K homology domain-like, alpha/beta BWK49_RS11460 5ffaa947ae8d45886c10c3b66970e75f 299 SUPERFAMILY SSF52540 9 200 3.08E-37 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS11460 5ffaa947ae8d45886c10c3b66970e75f 299 SUPERFAMILY SSF54814 183 299 1.11E-36 T 06-07-2017 IPR009019 K homology domain, prokaryotic type GO:0003723 BWK49_RS11460 5ffaa947ae8d45886c10c3b66970e75f 299 Pfam PF07650 KH domain 209 288 1.1E-19 T 06-07-2017 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 BWK49_RS11460 5ffaa947ae8d45886c10c3b66970e75f 299 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 85 100 9.1E-6 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 BWK49_RS11460 5ffaa947ae8d45886c10c3b66970e75f 299 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 9 29 9.1E-6 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 BWK49_RS11460 5ffaa947ae8d45886c10c3b66970e75f 299 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 8 168 1.5E-17 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 BWK49_RS11460 5ffaa947ae8d45886c10c3b66970e75f 299 TIGRFAM TIGR00436 era: GTP-binding protein Era 7 282 6.4E-71 T 06-07-2017 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 BWK49_RS12045 8bfc84aba2afdb7409fd43b74c961f96 514 Pfam PF07731 Multicopper oxidase 404 513 1.7E-21 T 06-07-2017 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 BWK49_RS12045 8bfc84aba2afdb7409fd43b74c961f96 514 SUPERFAMILY SSF49503 215 346 1.28E-25 T 06-07-2017 IPR008972 Cupredoxin BWK49_RS12045 8bfc84aba2afdb7409fd43b74c961f96 514 Gene3D G3DSA:2.60.40.420 215 342 9.2E-34 T 06-07-2017 IPR008972 Cupredoxin BWK49_RS12045 8bfc84aba2afdb7409fd43b74c961f96 514 ProSitePatterns PS00080 Multicopper oxidases signature 2. 496 507 - T 06-07-2017 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 BWK49_RS12045 8bfc84aba2afdb7409fd43b74c961f96 514 SUPERFAMILY SSF49503 401 511 1.79E-29 T 06-07-2017 IPR008972 Cupredoxin BWK49_RS12045 8bfc84aba2afdb7409fd43b74c961f96 514 Gene3D G3DSA:2.60.40.420 57 214 6.2E-26 T 06-07-2017 IPR008972 Cupredoxin BWK49_RS12045 8bfc84aba2afdb7409fd43b74c961f96 514 Gene3D G3DSA:2.60.40.420 388 512 3.2E-33 T 06-07-2017 IPR008972 Cupredoxin BWK49_RS12045 8bfc84aba2afdb7409fd43b74c961f96 514 Pfam PF07732 Multicopper oxidase 85 141 5.0E-10 T 06-07-2017 IPR011707 Multicopper oxidase, type 3 GO:0005507 BWK49_RS12045 8bfc84aba2afdb7409fd43b74c961f96 514 Pfam PF07732 Multicopper oxidase 169 211 2.6E-5 T 06-07-2017 IPR011707 Multicopper oxidase, type 3 GO:0005507 BWK49_RS12045 8bfc84aba2afdb7409fd43b74c961f96 514 SUPERFAMILY SSF49503 47 212 1.39E-22 T 06-07-2017 IPR008972 Cupredoxin BWK49_RS16365 b0d42fd110d779903091eb9782788e6f 312 PRINTS PR00111 Alpha/beta hydrolase fold signature 131 144 1.7E-11 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS16365 b0d42fd110d779903091eb9782788e6f 312 PRINTS PR00111 Alpha/beta hydrolase fold signature 73 88 1.7E-11 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS16365 b0d42fd110d779903091eb9782788e6f 312 PRINTS PR00111 Alpha/beta hydrolase fold signature 117 130 1.7E-11 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS16365 b0d42fd110d779903091eb9782788e6f 312 SUPERFAMILY SSF53474 26 307 5.13E-60 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS16365 b0d42fd110d779903091eb9782788e6f 312 Gene3D G3DSA:3.40.50.1820 27 310 6.0E-62 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS16365 b0d42fd110d779903091eb9782788e6f 312 PRINTS PR00412 Epoxide hydrolase signature 285 307 5.7E-5 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS16365 b0d42fd110d779903091eb9782788e6f 312 PRINTS PR00412 Epoxide hydrolase signature 117 130 5.7E-5 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS16365 b0d42fd110d779903091eb9782788e6f 312 PRINTS PR00412 Epoxide hydrolase signature 54 72 5.7E-5 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS16365 b0d42fd110d779903091eb9782788e6f 312 Pfam PF00561 alpha/beta hydrolase fold 49 297 9.3E-26 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS22975 d466f6c72aed6846d400ed67c664312d 408 Gene3D G3DSA:2.60.120.10 297 406 5.2E-18 T 06-07-2017 IPR014710 RmlC-like jelly roll fold BWK49_RS22975 d466f6c72aed6846d400ed67c664312d 408 SUPERFAMILY SSF51182 3 389 1.95E-95 T 06-07-2017 IPR011051 RmlC-like cupin domain BWK49_RS22975 d466f6c72aed6846d400ed67c664312d 408 Gene3D G3DSA:2.60.120.10 247 282 2.0E-54 T 06-07-2017 IPR014710 RmlC-like jelly roll fold BWK49_RS22975 d466f6c72aed6846d400ed67c664312d 408 Gene3D G3DSA:2.60.120.10 7 140 2.0E-54 T 06-07-2017 IPR014710 RmlC-like jelly roll fold BWK49_RS22975 d466f6c72aed6846d400ed67c664312d 408 PIRSF PIRSF001480 1 408 4.2E-104 T 06-07-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 BWK49_RS22975 d466f6c72aed6846d400ed67c664312d 408 Gene3D G3DSA:1.10.441.10 283 296 4.9E-23 T 06-07-2017 BWK49_RS22975 d466f6c72aed6846d400ed67c664312d 408 Gene3D G3DSA:1.10.441.10 141 240 4.9E-23 T 06-07-2017 BWK49_RS22975 d466f6c72aed6846d400ed67c664312d 408 Pfam PF01238 Phosphomannose isomerase type I 5 368 7.0E-62 T 06-07-2017 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 BWK49_RS22975 d466f6c72aed6846d400ed67c664312d 408 TIGRFAM TIGR00218 manA: mannose-6-phosphate isomerase, class I 7 396 2.2E-67 T 06-07-2017 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 BWK49_RS22975 d466f6c72aed6846d400ed67c664312d 408 PRINTS PR00714 Phosphomannose isomerase type I signature 81 102 3.3E-63 T 06-07-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 BWK49_RS22975 d466f6c72aed6846d400ed67c664312d 408 PRINTS PR00714 Phosphomannose isomerase type I signature 126 149 3.3E-63 T 06-07-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 BWK49_RS22975 d466f6c72aed6846d400ed67c664312d 408 PRINTS PR00714 Phosphomannose isomerase type I signature 4 22 3.3E-63 T 06-07-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 BWK49_RS22975 d466f6c72aed6846d400ed67c664312d 408 PRINTS PR00714 Phosphomannose isomerase type I signature 283 302 3.3E-63 T 06-07-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 BWK49_RS22975 d466f6c72aed6846d400ed67c664312d 408 PRINTS PR00714 Phosphomannose isomerase type I signature 264 283 3.3E-63 T 06-07-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 BWK49_RS22975 d466f6c72aed6846d400ed67c664312d 408 PRINTS PR00714 Phosphomannose isomerase type I signature 229 244 3.3E-63 T 06-07-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 BWK49_RS22975 d466f6c72aed6846d400ed67c664312d 408 PRINTS PR00714 Phosphomannose isomerase type I signature 32 47 3.3E-63 T 06-07-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 BWK49_RS22975 d466f6c72aed6846d400ed67c664312d 408 PRINTS PR00714 Phosphomannose isomerase type I signature 245 264 3.3E-63 T 06-07-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 BWK49_RS20820 6348682b43c97ba75f869fd4869b305d 227 TIGRFAM TIGR00628 ung: uracil-DNA glycosylase 14 216 8.0E-60 T 06-07-2017 IPR002043 Uracil-DNA glycosylase GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 BWK49_RS20820 6348682b43c97ba75f869fd4869b305d 227 SUPERFAMILY SSF52141 9 226 8.72E-73 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 BWK49_RS20820 6348682b43c97ba75f869fd4869b305d 227 Pfam PF03167 Uracil DNA glycosylase superfamily 55 213 4.0E-18 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 BWK49_RS20820 6348682b43c97ba75f869fd4869b305d 227 Gene3D G3DSA:3.40.470.10 5 226 5.1E-81 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 BWK49_RS20820 6348682b43c97ba75f869fd4869b305d 227 SMART SM00987 53 214 3.1E-34 T 06-07-2017 BWK49_RS20820 6348682b43c97ba75f869fd4869b305d 227 SMART SM00986 53 214 3.1E-34 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 BWK49_RS20820 6348682b43c97ba75f869fd4869b305d 227 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 61 70 - T 06-07-2017 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 BWK49_RS20820 6348682b43c97ba75f869fd4869b305d 227 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 11 225 33.848 T 06-07-2017 IPR002043 Uracil-DNA glycosylase GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 BWK49_RS24410 40b8de3384e4cc18d2e28902c972ce14 286 Pfam PF09851 Short C-terminal domain 257 282 2.5E-6 T 06-07-2017 IPR018649 SHOCT domain BWK49_RS06540 ed385ca52f2f99a9f714b9540f3eaa14 97 Gene3D G3DSA:3.30.70.900 1 89 4.6E-13 T 06-07-2017 BWK49_RS06540 ed385ca52f2f99a9f714b9540f3eaa14 97 Pfam PF03992 Antibiotic biosynthesis monooxygenase 3 68 1.3E-9 T 06-07-2017 IPR007138 Antibiotic biosynthesis monooxygenase domain BWK49_RS06540 ed385ca52f2f99a9f714b9540f3eaa14 97 SUPERFAMILY SSF54909 3 92 9.91E-16 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel BWK49_RS09440 6a9ce7e6a69fb5c013a5c79703b64933 218 SUPERFAMILY SSF48498 94 205 3.34E-7 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS09440 6a9ce7e6a69fb5c013a5c79703b64933 218 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 70 1.9E-15 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS09440 6a9ce7e6a69fb5c013a5c79703b64933 218 SUPERFAMILY SSF46689 11 89 1.03E-19 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS09440 6a9ce7e6a69fb5c013a5c79703b64933 218 Gene3D G3DSA:1.10.357.10 20 205 4.2E-38 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS09440 6a9ce7e6a69fb5c013a5c79703b64933 218 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 68 1.0E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS09440 6a9ce7e6a69fb5c013a5c79703b64933 218 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 24 37 1.0E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS05355 a3018a7e47f7fe2015193d995202388b 558 Gene3D G3DSA:2.30.38.10 372 448 8.8E-17 T 06-07-2017 BWK49_RS05355 a3018a7e47f7fe2015193d995202388b 558 Gene3D G3DSA:3.40.50.980 202 349 1.4E-29 T 06-07-2017 BWK49_RS05355 a3018a7e47f7fe2015193d995202388b 558 Pfam PF13193 AMP-binding enzyme C-terminal domain 465 539 8.8E-17 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS05355 a3018a7e47f7fe2015193d995202388b 558 SUPERFAMILY SSF56801 15 553 1.7E-125 T 06-07-2017 BWK49_RS05355 a3018a7e47f7fe2015193d995202388b 558 Gene3D G3DSA:3.30.300.30 450 548 5.1E-25 T 06-07-2017 BWK49_RS05355 a3018a7e47f7fe2015193d995202388b 558 Pfam PF00501 AMP-binding enzyme 26 455 2.6E-78 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS05355 a3018a7e47f7fe2015193d995202388b 558 Gene3D G3DSA:3.40.50.980 22 201 6.0E-27 T 06-07-2017 BWK49_RS08325 fcf6057680d66cdb9ce20cdf7029a375 2130 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 545 840 1.2E-89 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain BWK49_RS08325 fcf6057680d66cdb9ce20cdf7029a375 2130 SUPERFAMILY SSF53901 4 376 2.45E-94 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS08325 fcf6057680d66cdb9ce20cdf7029a375 2130 Gene3D G3DSA:3.40.366.10 540 661 4.3E-65 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 BWK49_RS08325 fcf6057680d66cdb9ce20cdf7029a375 2130 Gene3D G3DSA:3.40.366.10 730 841 4.3E-65 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 BWK49_RS08325 fcf6057680d66cdb9ce20cdf7029a375 2130 Gene3D G3DSA:3.40.50.720 1783 1989 3.2E-34 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS08325 fcf6057680d66cdb9ce20cdf7029a375 2130 SMART SM00829 1448 1760 2.8E-154 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 BWK49_RS08325 fcf6057680d66cdb9ce20cdf7029a375 2130 Pfam PF08659 KR domain 1784 1966 1.9E-57 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS08325 fcf6057680d66cdb9ce20cdf7029a375 2130 Gene3D G3DSA:3.40.47.10 5 268 4.1E-89 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS08325 fcf6057680d66cdb9ce20cdf7029a375 2130 SUPERFAMILY SSF47336 2046 2122 1.44E-12 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS08325 fcf6057680d66cdb9ce20cdf7029a375 2130 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 264 377 1.3E-37 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal BWK49_RS08325 fcf6057680d66cdb9ce20cdf7029a375 2130 Pfam PF00698 Acyl transferase domain 543 839 3.1E-92 T 06-07-2017 IPR014043 Acyl transferase BWK49_RS08325 fcf6057680d66cdb9ce20cdf7029a375 2130 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 389 476 5.5E-11 T 06-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS08325 fcf6057680d66cdb9ce20cdf7029a375 2130 Pfam PF00107 Zinc-binding dehydrogenase 1589 1679 1.9E-21 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 BWK49_RS08325 fcf6057680d66cdb9ce20cdf7029a375 2130 SUPERFAMILY SSF52151 732 828 3.92E-61 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 BWK49_RS08325 fcf6057680d66cdb9ce20cdf7029a375 2130 SUPERFAMILY SSF52151 543 667 3.92E-61 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 BWK49_RS08325 fcf6057680d66cdb9ce20cdf7029a375 2130 SUPERFAMILY SSF51735 1201 1422 9.45E-33 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS08325 fcf6057680d66cdb9ce20cdf7029a375 2130 Gene3D G3DSA:3.40.50.720 1583 1676 4.6E-25 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS08325 fcf6057680d66cdb9ce20cdf7029a375 2130 SUPERFAMILY SSF50129 1444 1577 2.2E-31 T 06-07-2017 IPR011032 GroES-like BWK49_RS08325 fcf6057680d66cdb9ce20cdf7029a375 2130 Pfam PF14765 Polyketide synthase dehydratase 912 1190 1.7E-55 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS08325 fcf6057680d66cdb9ce20cdf7029a375 2130 Gene3D G3DSA:3.90.180.10 1445 1582 3.3E-42 T 06-07-2017 IPR011032 GroES-like BWK49_RS08325 fcf6057680d66cdb9ce20cdf7029a375 2130 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1784 1967 2.4E-44 T 06-07-2017 BWK49_RS08325 fcf6057680d66cdb9ce20cdf7029a375 2130 SUPERFAMILY SSF51735 1780 2019 1.51E-37 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS08325 fcf6057680d66cdb9ce20cdf7029a375 2130 SUPERFAMILY SSF51735 1553 1704 8.35E-40 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS08325 fcf6057680d66cdb9ce20cdf7029a375 2130 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 7 256 4.3E-86 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal BWK49_RS08325 fcf6057680d66cdb9ce20cdf7029a375 2130 Gene3D G3DSA:1.10.1200.10 2053 2121 5.3E-14 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS08325 fcf6057680d66cdb9ce20cdf7029a375 2130 Gene3D G3DSA:3.40.47.10 269 431 1.7E-53 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS08325 fcf6057680d66cdb9ce20cdf7029a375 2130 Pfam PF00550 Phosphopantetheine attachment site 2053 2116 6.9E-9 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS08325 fcf6057680d66cdb9ce20cdf7029a375 2130 SMART SM00826 912 1075 3.2E-37 T 06-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS08325 fcf6057680d66cdb9ce20cdf7029a375 2130 SMART SM00825 Beta-ketoacyl synthase 9 431 4.3E-185 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain BWK49_RS08325 fcf6057680d66cdb9ce20cdf7029a375 2130 SMART SM00823 Phosphopantetheine attachment site 2055 2120 1.2E-13 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS08325 fcf6057680d66cdb9ce20cdf7029a375 2130 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 1465 1531 2.2E-5 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 BWK49_RS08325 fcf6057680d66cdb9ce20cdf7029a375 2130 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 169 185 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site BWK49_RS08325 fcf6057680d66cdb9ce20cdf7029a375 2130 SUPERFAMILY SSF55048 665 731 1.31E-6 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 BWK49_RS09075 29c396b85a8ede02747b0120651226ea 302 Gene3D G3DSA:3.40.30.10 50 147 9.0E-17 T 06-07-2017 IPR012336 Thioredoxin-like fold BWK49_RS09075 29c396b85a8ede02747b0120651226ea 302 Pfam PF00085 Thioredoxin 44 145 6.1E-9 T 06-07-2017 IPR013766 Thioredoxin domain GO:0045454 BWK49_RS09075 29c396b85a8ede02747b0120651226ea 302 SUPERFAMILY SSF52833 37 149 2.15E-19 T 06-07-2017 IPR012336 Thioredoxin-like fold BWK49_RS09075 29c396b85a8ede02747b0120651226ea 302 Gene3D G3DSA:1.25.40.10 228 302 2.2E-11 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 BWK49_RS09075 29c396b85a8ede02747b0120651226ea 302 Pfam PF14561 Tetratricopeptide repeat 225 302 9.7E-17 T 06-07-2017 BWK49_RS17480 5468a9264f1d0a62af8eaea74acd94c1 226 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 27 176 1.4E-43 T 06-07-2017 IPR024747 Pyridoxamine 5'-phosphate oxidase-related BWK49_RS17480 5468a9264f1d0a62af8eaea74acd94c1 226 Gene3D G3DSA:2.30.110.10 7 197 1.5E-71 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 BWK49_RS17480 5468a9264f1d0a62af8eaea74acd94c1 226 SUPERFAMILY SSF50475 8 197 1.33E-55 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 BWK49_RS23550 25bd1422e4eadf476942893ab8a02360 281 Gene3D G3DSA:3.40.50.720 138 263 1.1E-43 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS23550 25bd1422e4eadf476942893ab8a02360 281 SUPERFAMILY SSF51735 122 279 2.56E-40 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS23550 25bd1422e4eadf476942893ab8a02360 281 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 123 280 1.8E-59 T 06-07-2017 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 BWK49_RS23550 25bd1422e4eadf476942893ab8a02360 281 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 33 55 7.8E-61 T 06-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 BWK49_RS23550 25bd1422e4eadf476942893ab8a02360 281 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 74 101 7.8E-61 T 06-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 BWK49_RS23550 25bd1422e4eadf476942893ab8a02360 281 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 154 174 7.8E-61 T 06-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 BWK49_RS23550 25bd1422e4eadf476942893ab8a02360 281 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 109 130 7.8E-61 T 06-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 BWK49_RS23550 25bd1422e4eadf476942893ab8a02360 281 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 255 273 7.8E-61 T 06-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 BWK49_RS23550 25bd1422e4eadf476942893ab8a02360 281 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 205 234 7.8E-61 T 06-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 BWK49_RS23550 25bd1422e4eadf476942893ab8a02360 281 Gene3D G3DSA:3.40.192.10 7 137 1.9E-41 T 06-07-2017 BWK49_RS23550 25bd1422e4eadf476942893ab8a02360 281 Hamap MF_01576 Bifunctional protein FolD [folD]. 3 281 34.289 T 06-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 BWK49_RS23550 25bd1422e4eadf476942893ab8a02360 281 SUPERFAMILY SSF53223 3 121 4.22E-34 T 06-07-2017 BWK49_RS23550 25bd1422e4eadf476942893ab8a02360 281 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 6 120 2.1E-33 T 06-07-2017 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 BWK49_RS26955 c28c1de388d779ff2ec5599c59d365d6 505 Pfam PF00501 AMP-binding enzyme 10 401 2.2E-65 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS26955 c28c1de388d779ff2ec5599c59d365d6 505 Gene3D G3DSA:3.30.300.30 396 493 6.0E-33 T 06-07-2017 BWK49_RS26955 c28c1de388d779ff2ec5599c59d365d6 505 Pfam PF13193 AMP-binding enzyme C-terminal domain 410 485 5.0E-22 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS26955 c28c1de388d779ff2ec5599c59d365d6 505 Gene3D G3DSA:2.30.38.10 322 391 1.0E-15 T 06-07-2017 BWK49_RS26955 c28c1de388d779ff2ec5599c59d365d6 505 Gene3D G3DSA:3.40.50.980 151 306 2.1E-37 T 06-07-2017 BWK49_RS26955 c28c1de388d779ff2ec5599c59d365d6 505 SUPERFAMILY SSF56801 6 498 4.71E-118 T 06-07-2017 BWK49_RS26955 c28c1de388d779ff2ec5599c59d365d6 505 ProSitePatterns PS00455 Putative AMP-binding domain signature. 144 155 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS26955 c28c1de388d779ff2ec5599c59d365d6 505 Gene3D G3DSA:3.40.50.980 3 150 5.7E-19 T 06-07-2017 BWK49_RS09925 505b1db9ad6c7edf95f2a66c94cc1477 305 SUPERFAMILY SSF82282 7 296 1.15E-77 T 06-07-2017 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 BWK49_RS09925 505b1db9ad6c7edf95f2a66c94cc1477 305 Pfam PF02574 Homocysteine S-methyltransferase 11 290 9.4E-71 T 06-07-2017 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 BWK49_RS09925 505b1db9ad6c7edf95f2a66c94cc1477 305 Gene3D G3DSA:3.20.20.330 7 297 3.9E-85 T 06-07-2017 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 BWK49_RS28970 af9be617eee17349c1b7b3cbb85435cc 1408 TIGRFAM TIGR03924 T7SS_EccC_a: type VII secretion protein EccCa 25 730 3.1E-173 T 06-07-2017 IPR023836 EccCa-like, Actinobacteria BWK49_RS28970 af9be617eee17349c1b7b3cbb85435cc 1408 SUPERFAMILY SSF52540 825 1071 7.61E-16 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS28970 af9be617eee17349c1b7b3cbb85435cc 1408 SUPERFAMILY SSF52540 464 709 1.21E-24 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS28970 af9be617eee17349c1b7b3cbb85435cc 1408 TIGRFAM TIGR03925 T7SS_EccC_b: type VII secretion protein EccCb 808 1393 4.0E-140 T 06-07-2017 IPR023837 EccCb-like, Actinobacteria BWK49_RS28970 af9be617eee17349c1b7b3cbb85435cc 1408 SMART SM00382 1180 1355 5.4 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS28970 af9be617eee17349c1b7b3cbb85435cc 1408 SMART SM00382 882 1062 0.009 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS28970 af9be617eee17349c1b7b3cbb85435cc 1408 SMART SM00382 500 685 0.32 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS28970 af9be617eee17349c1b7b3cbb85435cc 1408 Gene3D G3DSA:3.40.50.300 871 1067 5.8E-11 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS28970 af9be617eee17349c1b7b3cbb85435cc 1408 Gene3D G3DSA:3.40.50.300 462 725 9.6E-25 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS28970 af9be617eee17349c1b7b3cbb85435cc 1408 Pfam PF01580 FtsK/SpoIIIE family 838 1110 1.7E-56 T 06-07-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 BWK49_RS28970 af9be617eee17349c1b7b3cbb85435cc 1408 Pfam PF01580 FtsK/SpoIIIE family 472 664 3.2E-22 T 06-07-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 BWK49_RS28970 af9be617eee17349c1b7b3cbb85435cc 1408 SUPERFAMILY SSF52540 1155 1342 1.34E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS20070 758c553f7805758f3246857de6335f4d 284 Pfam PF08445 FR47-like protein 214 275 2.5E-8 T 06-07-2017 IPR013653 FR47-like GO:0016747 BWK49_RS20070 758c553f7805758f3246857de6335f4d 284 Gene3D G3DSA:3.40.630.30 134 279 3.2E-18 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase BWK49_RS20070 758c553f7805758f3246857de6335f4d 284 Pfam PF13312 Domain of unknown function (DUF4081) 54 156 4.3E-40 T 06-07-2017 IPR025289 Domain of unknown function DUF4081 BWK49_RS20070 758c553f7805758f3246857de6335f4d 284 PIRSF PIRSF021603 1 283 8.2E-137 T 06-07-2017 IPR016794 Uncharacterised conserved protein UCP21603, acetyltransferase-like BWK49_RS20070 758c553f7805758f3246857de6335f4d 284 SUPERFAMILY SSF55729 143 278 1.95E-15 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase BWK49_RS07785 a6beb82a60731e6294af78c5c7c9e427 312 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 92 239 1.3E-11 T 06-07-2017 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 BWK49_RS07785 a6beb82a60731e6294af78c5c7c9e427 312 PIRSF PIRSF000545 1 312 1.8E-140 T 06-07-2017 IPR004566 Bacterial pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 BWK49_RS07785 a6beb82a60731e6294af78c5c7c9e427 312 Hamap MF_00215 Pantothenate kinase [coaA]. 1 312 173.932 T 06-07-2017 IPR004566 Bacterial pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 BWK49_RS07785 a6beb82a60731e6294af78c5c7c9e427 312 Gene3D G3DSA:3.40.50.300 8 311 4.5E-101 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS07785 a6beb82a60731e6294af78c5c7c9e427 312 SUPERFAMILY SSF52540 5 310 5.33E-68 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS07785 a6beb82a60731e6294af78c5c7c9e427 312 TIGRFAM TIGR00554 panK_bact: pantothenate kinase 9 311 4.9E-120 T 06-07-2017 IPR004566 Bacterial pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 BWK49_RS03905 86073bb445617615d72304abeea600e9 534 Gene3D G3DSA:1.20.1250.20 290 449 3.0E-23 T 06-07-2017 BWK49_RS03905 86073bb445617615d72304abeea600e9 534 Gene3D G3DSA:1.20.1250.20 501 530 3.0E-23 T 06-07-2017 BWK49_RS03905 86073bb445617615d72304abeea600e9 534 Gene3D G3DSA:1.20.1250.20 40 216 1.9E-25 T 06-07-2017 BWK49_RS03905 86073bb445617615d72304abeea600e9 534 Pfam PF07690 Major Facilitator Superfamily 44 438 1.6E-48 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 BWK49_RS03905 86073bb445617615d72304abeea600e9 534 SUPERFAMILY SSF103473 276 448 6.02E-68 T 06-07-2017 IPR020846 Major facilitator superfamily domain BWK49_RS03905 86073bb445617615d72304abeea600e9 534 SUPERFAMILY SSF103473 41 225 6.02E-68 T 06-07-2017 IPR020846 Major facilitator superfamily domain BWK49_RS03905 86073bb445617615d72304abeea600e9 534 SUPERFAMILY SSF103473 499 531 6.02E-68 T 06-07-2017 IPR020846 Major facilitator superfamily domain BWK49_RS03905 86073bb445617615d72304abeea600e9 534 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 38 523 5.4E-150 T 06-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 BWK49_RS22585 558118bcebc29721f2d2cc2e668c27b5 216 SUPERFAMILY SSF109604 25 133 1.8E-15 T 06-07-2017 BWK49_RS22585 558118bcebc29721f2d2cc2e668c27b5 216 Pfam PF01966 HD domain 36 121 1.2E-8 T 06-07-2017 IPR006674 HD domain BWK49_RS22585 558118bcebc29721f2d2cc2e668c27b5 216 Gene3D G3DSA:1.10.3210.10 35 139 2.1E-8 T 06-07-2017 IPR006674 HD domain BWK49_RS07190 cf6d1be6053ea580a797e9eef437b68d 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 64 1.3E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS07190 cf6d1be6053ea580a797e9eef437b68d 202 Gene3D G3DSA:1.10.357.10 13 192 2.2E-18 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS07190 cf6d1be6053ea580a797e9eef437b68d 202 SUPERFAMILY SSF46689 12 81 4.64E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS20755 65abff675927a7f0fd5ff732d6f2102b 262 Gene3D G3DSA:3.20.20.100 1 258 4.2E-86 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain BWK49_RS20755 65abff675927a7f0fd5ff732d6f2102b 262 Pfam PF00248 Aldo/keto reductase family 10 247 1.1E-40 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain BWK49_RS20755 65abff675927a7f0fd5ff732d6f2102b 262 SUPERFAMILY SSF51430 1 255 1.96E-77 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain BWK49_RS20755 65abff675927a7f0fd5ff732d6f2102b 262 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 111 128 - T 06-07-2017 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 BWK49_RS20755 65abff675927a7f0fd5ff732d6f2102b 262 PRINTS PR00069 Aldo-keto reductase signature 111 128 3.1E-44 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 BWK49_RS20755 65abff675927a7f0fd5ff732d6f2102b 262 PRINTS PR00069 Aldo-keto reductase signature 145 174 3.1E-44 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 BWK49_RS20755 65abff675927a7f0fd5ff732d6f2102b 262 PRINTS PR00069 Aldo-keto reductase signature 23 47 3.1E-44 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 BWK49_RS20755 65abff675927a7f0fd5ff732d6f2102b 262 PRINTS PR00069 Aldo-keto reductase signature 182 206 3.1E-44 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 BWK49_RS20755 65abff675927a7f0fd5ff732d6f2102b 262 PRINTS PR00069 Aldo-keto reductase signature 79 97 3.1E-44 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 BWK49_RS10660 cdf467ce175d0405b1abd90e007cd7e1 658 Pfam PF01436 NHL repeat 544 570 5.1E-5 T 06-07-2017 IPR001258 NHL repeat GO:0005515 BWK49_RS10660 cdf467ce175d0405b1abd90e007cd7e1 658 Pfam PF01436 NHL repeat 461 482 1.7E-5 T 06-07-2017 IPR001258 NHL repeat GO:0005515 BWK49_RS10660 cdf467ce175d0405b1abd90e007cd7e1 658 Pfam PF01436 NHL repeat 587 610 1.6E-4 T 06-07-2017 IPR001258 NHL repeat GO:0005515 BWK49_RS10660 cdf467ce175d0405b1abd90e007cd7e1 658 Pfam PF01436 NHL repeat 502 528 8.7E-7 T 06-07-2017 IPR001258 NHL repeat GO:0005515 BWK49_RS10660 cdf467ce175d0405b1abd90e007cd7e1 658 SMART SM00135 579 618 8.5 T 06-07-2017 IPR000033 LDLR class B repeat BWK49_RS10660 cdf467ce175d0405b1abd90e007cd7e1 658 SMART SM00135 495 534 42.0 T 06-07-2017 IPR000033 LDLR class B repeat BWK49_RS10660 cdf467ce175d0405b1abd90e007cd7e1 658 SMART SM00135 537 576 3.9 T 06-07-2017 IPR000033 LDLR class B repeat BWK49_RS10660 cdf467ce175d0405b1abd90e007cd7e1 658 SMART SM00135 454 492 64.0 T 06-07-2017 IPR000033 LDLR class B repeat BWK49_RS10660 cdf467ce175d0405b1abd90e007cd7e1 658 Pfam PF00069 Protein kinase domain 17 263 6.3E-41 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 BWK49_RS10660 cdf467ce175d0405b1abd90e007cd7e1 658 SUPERFAMILY SSF56112 14 356 1.25E-67 T 06-07-2017 IPR011009 Protein kinase-like domain BWK49_RS10660 cdf467ce175d0405b1abd90e007cd7e1 658 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 23 46 - T 06-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 BWK49_RS10660 cdf467ce175d0405b1abd90e007cd7e1 658 SMART SM00220 17 278 9.4E-50 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 BWK49_RS10660 cdf467ce175d0405b1abd90e007cd7e1 658 SUPERFAMILY SSF63829 419 650 7.19E-40 T 06-07-2017 BWK49_RS10660 cdf467ce175d0405b1abd90e007cd7e1 658 Gene3D G3DSA:1.10.510.10 115 330 3.5E-40 T 06-07-2017 BWK49_RS10660 cdf467ce175d0405b1abd90e007cd7e1 658 Gene3D G3DSA:2.120.10.30 419 652 7.8E-51 T 06-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like BWK49_RS10660 cdf467ce175d0405b1abd90e007cd7e1 658 Gene3D G3DSA:3.30.200.20 12 114 4.0E-21 T 06-07-2017 BWK49_RS10660 cdf467ce175d0405b1abd90e007cd7e1 658 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 136 148 - T 06-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 BWK49_RS03075 be338a88010d4d61e76ceab98db00a00 158 Pfam PF11377 Protein of unknown function (DUF3180) 9 146 6.7E-41 T 06-07-2017 IPR021517 Protein of unknown function DUF3180 BWK49_RS07350 3f07578ea733cd2a88d74f17c38fccf7 528 Pfam PF02397 Bacterial sugar transferase 334 522 2.4E-57 T 06-07-2017 IPR003362 Bacterial sugar transferase BWK49_RS07350 3f07578ea733cd2a88d74f17c38fccf7 528 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 68 528 5.6E-127 T 06-07-2017 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase BWK49_RS08260 937d5aad7324c2e90963b869ee63b620 222 TIGRFAM TIGR00684 narJ: nitrate reductase molybdenum cofactor assembly chaperone 26 176 9.4E-54 T 06-07-2017 IPR003765 Nitrate reductase chaperone, NarJ GO:0051082|GO:0051131 BWK49_RS08260 937d5aad7324c2e90963b869ee63b620 222 SUPERFAMILY SSF89155 20 181 2.49E-27 T 06-07-2017 IPR020945 DMSO/Nitrate reductase chaperone BWK49_RS08260 937d5aad7324c2e90963b869ee63b620 222 Pfam PF02613 Nitrate reductase delta subunit 53 170 5.0E-11 T 06-07-2017 IPR020945 DMSO/Nitrate reductase chaperone BWK49_RS08260 937d5aad7324c2e90963b869ee63b620 222 Gene3D G3DSA:1.10.3480.10 25 139 1.8E-8 T 06-07-2017 IPR020945 DMSO/Nitrate reductase chaperone BWK49_RS08455 b44c1597dc56a3645cd276c6a759943f 187 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 11 185 8.2E-66 T 06-07-2017 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG BWK49_RS08455 b44c1597dc56a3645cd276c6a759943f 187 Gene3D G3DSA:3.40.50.450 9 182 4.5E-52 T 06-07-2017 BWK49_RS08455 b44c1597dc56a3645cd276c6a759943f 187 Pfam PF03641 Possible lysine decarboxylase 54 183 4.8E-36 T 06-07-2017 IPR031100 LOG family BWK49_RS08455 b44c1597dc56a3645cd276c6a759943f 187 SUPERFAMILY SSF102405 11 183 1.37E-50 T 06-07-2017 BWK49_RS23010 9a36b57236dd3adbd34805a9800404a5 333 Pfam PF01933 Uncharacterised protein family UPF0052 3 295 2.6E-64 T 06-07-2017 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 BWK49_RS23010 9a36b57236dd3adbd34805a9800404a5 333 SUPERFAMILY SSF142338 3 329 6.54E-81 T 06-07-2017 BWK49_RS23010 9a36b57236dd3adbd34805a9800404a5 333 Hamap MF_01257 2-phospho-L-lactate transferase [cofD]. 1 333 137.032 T 06-07-2017 IPR010115 2-phospho-L-lactate transferase GO:0000287|GO:0016780|GO:0051188 KEGG: 00680+2.7.8.28|MetaCyc: PWY-5198 BWK49_RS23010 9a36b57236dd3adbd34805a9800404a5 333 TIGRFAM TIGR01819 F420_cofD: 2-phospho-L-lactate transferase 3 326 1.7E-127 T 06-07-2017 IPR010115 2-phospho-L-lactate transferase GO:0000287|GO:0016780|GO:0051188 KEGG: 00680+2.7.8.28|MetaCyc: PWY-5198 BWK49_RS23010 9a36b57236dd3adbd34805a9800404a5 333 Gene3D G3DSA:3.40.50.10680 102 330 3.3E-77 T 06-07-2017 BWK49_RS28935 1664420827e51536cb2a5fd45a498cad 443 ProSitePatterns PS01007 Transposases, Mutator family, signature. 268 292 - T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 BWK49_RS28935 1664420827e51536cb2a5fd45a498cad 443 Pfam PF00872 Transposase, Mutator family 49 409 4.2E-129 T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 BWK49_RS04925 34665bd139d4235b227cf01230c33b37 347 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 149 277 1.5E-7 T 06-07-2017 IPR024516 Mammalian cell entry, C-terminal BWK49_RS04925 34665bd139d4235b227cf01230c33b37 347 Pfam PF02470 MlaD protein 37 113 1.0E-17 T 06-07-2017 IPR003399 Mce/MlaD BWK49_RS04925 34665bd139d4235b227cf01230c33b37 347 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 14 297 9.5E-78 T 06-07-2017 IPR005693 Virulence factor Mce protein BWK49_RS06970 8bdc7f6151633979f34f844bf89c8ab5 350 Gene3D G3DSA:2.70.70.10 208 340 2.6E-44 T 06-07-2017 BWK49_RS06970 8bdc7f6151633979f34f844bf89c8ab5 350 Pfam PF01551 Peptidase family M23 240 334 7.2E-31 T 06-07-2017 IPR016047 Peptidase M23 BWK49_RS06970 8bdc7f6151633979f34f844bf89c8ab5 350 SUPERFAMILY SSF51261 211 338 1.78E-48 T 06-07-2017 IPR011055 Duplicated hybrid motif BWK49_RS02680 3ae537084afd4db971401651b2dde3a3 190 SMART SM00331 9 185 0.0048 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 BWK49_RS02680 3ae537084afd4db971401651b2dde3a3 190 SUPERFAMILY SSF81606 13 183 1.09E-7 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 BWK49_RS02680 3ae537084afd4db971401651b2dde3a3 190 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 21 150 7.5E-10 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 BWK49_RS13690 8a0047865c559f6f0d0b273038f72c44 272 TIGRFAM TIGR03971 SDR_subfam_1: SDR family mycofactocin-dependent oxidoreductase 9 271 3.0E-103 T 06-07-2017 IPR023985 Mycofactocin-dependent oxidoreductase BWK49_RS13690 8a0047865c559f6f0d0b273038f72c44 272 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 159 187 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS13690 8a0047865c559f6f0d0b273038f72c44 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 3.7E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS13690 8a0047865c559f6f0d0b273038f72c44 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 233 253 3.7E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS13690 8a0047865c559f6f0d0b273038f72c44 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 99 110 3.7E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS13690 8a0047865c559f6f0d0b273038f72c44 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 193 210 3.7E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS13690 8a0047865c559f6f0d0b273038f72c44 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 191 3.7E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS13690 8a0047865c559f6f0d0b273038f72c44 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 146 162 3.7E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS13690 8a0047865c559f6f0d0b273038f72c44 272 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 270 2.4E-52 T 06-07-2017 BWK49_RS13690 8a0047865c559f6f0d0b273038f72c44 272 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 172 191 2.5E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS13690 8a0047865c559f6f0d0b273038f72c44 272 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 99 110 2.5E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS13690 8a0047865c559f6f0d0b273038f72c44 272 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 160 2.5E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS13690 8a0047865c559f6f0d0b273038f72c44 272 SUPERFAMILY SSF51735 6 271 5.26E-70 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS13690 8a0047865c559f6f0d0b273038f72c44 272 Gene3D G3DSA:3.40.50.720 5 271 1.1E-73 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS26780 fe5e6ea53a61a74731dd7f66191c073b 587 Pfam PF05199 GMC oxidoreductase 438 573 8.2E-32 T 06-07-2017 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 BWK49_RS26780 fe5e6ea53a61a74731dd7f66191c073b 587 Gene3D G3DSA:3.50.50.60 516 583 4.8E-93 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS26780 fe5e6ea53a61a74731dd7f66191c073b 587 Gene3D G3DSA:3.50.50.60 210 335 4.8E-93 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS26780 fe5e6ea53a61a74731dd7f66191c073b 587 Gene3D G3DSA:3.50.50.60 13 138 4.8E-93 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS26780 fe5e6ea53a61a74731dd7f66191c073b 587 SUPERFAMILY SSF51905 522 583 2.59E-60 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS26780 fe5e6ea53a61a74731dd7f66191c073b 587 SUPERFAMILY SSF51905 13 310 2.59E-60 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS26780 fe5e6ea53a61a74731dd7f66191c073b 587 SUPERFAMILY SSF54373 312 523 4.61E-31 T 06-07-2017 BWK49_RS26780 fe5e6ea53a61a74731dd7f66191c073b 587 PIRSF PIRSF000137 1 587 3.8E-159 T 06-07-2017 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 KEGG: 00260+1.2.1.8+1.1.99.1|MetaCyc: PWY-3722|MetaCyc: PWY-7494|Reactome: R-HSA-6798163 BWK49_RS26780 fe5e6ea53a61a74731dd7f66191c073b 587 Pfam PF00732 GMC oxidoreductase 14 317 2.6E-51 T 06-07-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 BWK49_RS26780 fe5e6ea53a61a74731dd7f66191c073b 587 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 276 290 - T 06-07-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 BWK49_RS16060 7e649e645134a874660eee20b35eb460 146 SMART SM00422 1 70 4.5E-29 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 BWK49_RS16060 7e649e645134a874660eee20b35eb460 146 Gene3D G3DSA:1.10.1660.10 56 130 8.8E-20 T 06-07-2017 BWK49_RS16060 7e649e645134a874660eee20b35eb460 146 Pfam PF00376 MerR family regulatory protein 2 39 1.7E-16 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 BWK49_RS16060 7e649e645134a874660eee20b35eb460 146 Pfam PF09278 MerR, DNA binding 44 108 1.4E-18 T 06-07-2017 IPR015358 Transcription regulator MerR, DNA binding BWK49_RS16060 7e649e645134a874660eee20b35eb460 146 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 5.6E-9 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 BWK49_RS16060 7e649e645134a874660eee20b35eb460 146 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 5.6E-9 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 BWK49_RS16060 7e649e645134a874660eee20b35eb460 146 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 5.6E-9 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 BWK49_RS16060 7e649e645134a874660eee20b35eb460 146 Gene3D G3DSA:1.10.1660.10 1 55 5.5E-24 T 06-07-2017 BWK49_RS16060 7e649e645134a874660eee20b35eb460 146 SUPERFAMILY SSF46955 1 114 9.16E-34 T 06-07-2017 IPR009061 Putative DNA-binding domain BWK49_RS00220 d05b1d18a7ce9e63a665d3b8b3ee06e2 105 Pfam PF10824 Excreted virulence factor EspC, type VII ESX diderm 1 98 1.6E-27 T 06-07-2017 IPR022536 ESX-1 secretion-associated protein EspC BWK49_RS00220 d05b1d18a7ce9e63a665d3b8b3ee06e2 105 ProDom PD069881 MB0028 RV0027/MT0030 1 105 5.0E-45 T 06-07-2017 BWK49_RS14370 c270a14010493378132722e758b75f8c 220 Gene3D G3DSA:3.40.50.150 22 175 2.2E-9 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS14370 c270a14010493378132722e758b75f8c 220 Pfam PF13578 Methyltransferase domain 45 173 4.1E-21 T 06-07-2017 BWK49_RS14370 c270a14010493378132722e758b75f8c 220 SUPERFAMILY SSF53335 21 194 4.66E-12 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS02315 c312cc17c79fd7382c48a351d810351b 329 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 21 318 1.2E-13 T 06-07-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 BWK49_RS02315 c312cc17c79fd7382c48a351d810351b 329 Gene3D G3DSA:3.40.50.720 121 292 1.3E-64 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS02315 c312cc17c79fd7382c48a351d810351b 329 SUPERFAMILY SSF51735 112 291 5.84E-56 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS02315 c312cc17c79fd7382c48a351d810351b 329 Gene3D G3DSA:3.40.50.720 1 120 9.6E-22 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS02315 c312cc17c79fd7382c48a351d810351b 329 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 119 291 1.3E-59 T 06-07-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 BWK49_RS02315 c312cc17c79fd7382c48a351d810351b 329 SUPERFAMILY SSF52283 1 144 2.55E-20 T 06-07-2017 BWK49_RS12070 8416ad7ba6b9fa727bcf258a29e7659b 242 ProDom PD066345 MB2591 RV2561/RV2562/MT2638 34 242 6.0E-105 T 06-07-2017 IPR020503 Uncharacterised protein family Rv2561 BWK49_RS12070 8416ad7ba6b9fa727bcf258a29e7659b 242 Pfam PF10851 Protein of unknown function (DUF2652) 34 149 2.0E-44 T 06-07-2017 IPR020503 Uncharacterised protein family Rv2561 BWK49_RS12070 8416ad7ba6b9fa727bcf258a29e7659b 242 Gene3D G3DSA:3.30.70.1230 5 184 6.2E-5 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 BWK49_RS01545 e0e3b7a15fe2208439e94723ef631cb2 417 Gene3D G3DSA:3.40.50.10540 314 405 3.4E-89 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS01545 e0e3b7a15fe2208439e94723ef631cb2 417 Gene3D G3DSA:3.40.50.10540 5 222 3.4E-89 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS01545 e0e3b7a15fe2208439e94723ef631cb2 417 Pfam PF02515 CoA-transferase family III 10 380 6.5E-101 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 BWK49_RS01545 e0e3b7a15fe2208439e94723ef631cb2 417 SUPERFAMILY SSF89796 8 405 5.23E-102 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS01545 e0e3b7a15fe2208439e94723ef631cb2 417 Gene3D G3DSA:3.30.1540.10 229 313 6.6E-14 T 06-07-2017 BWK49_RS27530 c3b0b46de1983117d61399404d09e63f 170 Pfam PF01625 Peptide methionine sulfoxide reductase 5 152 1.2E-56 T 06-07-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 BWK49_RS27530 c3b0b46de1983117d61399404d09e63f 170 SUPERFAMILY SSF55068 4 161 5.76E-65 T 06-07-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 BWK49_RS27530 c3b0b46de1983117d61399404d09e63f 170 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 5 152 9.5E-49 T 06-07-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 BWK49_RS27530 c3b0b46de1983117d61399404d09e63f 170 Gene3D G3DSA:3.30.1060.10 3 153 7.3E-66 T 06-07-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 BWK49_RS27530 c3b0b46de1983117d61399404d09e63f 170 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 3 158 33.649 T 06-07-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 BWK49_RS19300 7ef299d98ef33ce424d93399384b085f 357 SUPERFAMILY SSF51726 18 356 2.62E-97 T 06-07-2017 BWK49_RS19300 7ef299d98ef33ce424d93399384b085f 357 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 17 357 44.027 T 06-07-2017 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 BWK49_RS19300 7ef299d98ef33ce424d93399384b085f 357 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 20 356 1.2E-123 T 06-07-2017 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 BWK49_RS19300 7ef299d98ef33ce424d93399384b085f 357 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 17 356 3.6E-121 T 06-07-2017 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 BWK49_RS19300 7ef299d98ef33ce424d93399384b085f 357 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 33 42 - T 06-07-2017 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 BWK49_RS19300 7ef299d98ef33ce424d93399384b085f 357 Gene3D G3DSA:3.20.20.210 9 356 1.3E-137 T 06-07-2017 BWK49_RS19300 7ef299d98ef33ce424d93399384b085f 357 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 150 166 - T 06-07-2017 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 BWK49_RS11645 39ac57b7e757b6830d98b1f6ddf53b45 505 SUPERFAMILY SSF111283 16 496 6.02E-91 T 06-07-2017 BWK49_RS11645 39ac57b7e757b6830d98b1f6ddf53b45 505 Pfam PF01523 Putative modulator of DNA gyrase 34 345 2.2E-47 T 06-07-2017 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 BWK49_RS20275 93863d8a8589f48425a2b4259e83e535 298 ProSitePatterns PS00761 Signal peptidases I signature 3. 228 241 - T 06-07-2017 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 BWK49_RS20275 93863d8a8589f48425a2b4259e83e535 298 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 65 282 2.2E-33 T 06-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 BWK49_RS20275 93863d8a8589f48425a2b4259e83e535 298 ProSitePatterns PS00501 Signal peptidases I serine active site. 89 96 - T 06-07-2017 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 BWK49_RS20275 93863d8a8589f48425a2b4259e83e535 298 Pfam PF00717 Peptidase S24-like 87 131 3.1E-6 T 06-07-2017 IPR019759 Peptidase S24/S26A/S26B BWK49_RS20275 93863d8a8589f48425a2b4259e83e535 298 SUPERFAMILY SSF51306 79 131 4.24E-44 T 06-07-2017 IPR015927 Peptidase S24/S26A/S26B/S26C BWK49_RS20275 93863d8a8589f48425a2b4259e83e535 298 SUPERFAMILY SSF51306 162 289 4.24E-44 T 06-07-2017 IPR015927 Peptidase S24/S26A/S26B/S26C BWK49_RS20275 93863d8a8589f48425a2b4259e83e535 298 Gene3D G3DSA:2.10.109.10 78 177 5.8E-37 T 06-07-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain BWK49_RS20275 93863d8a8589f48425a2b4259e83e535 298 Gene3D G3DSA:2.10.109.10 223 292 5.8E-37 T 06-07-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain BWK49_RS20275 93863d8a8589f48425a2b4259e83e535 298 Pfam PF10502 Signal peptidase, peptidase S26 159 256 2.5E-5 T 06-07-2017 IPR019533 Peptidase S26 BWK49_RS20275 93863d8a8589f48425a2b4259e83e535 298 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 167 179 1.7E-21 T 06-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 BWK49_RS20275 93863d8a8589f48425a2b4259e83e535 298 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 223 242 1.7E-21 T 06-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 BWK49_RS20275 93863d8a8589f48425a2b4259e83e535 298 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 80 96 1.7E-21 T 06-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 BWK49_RS16865 2ddf64cd1820536803fb1277f9c281b1 357 Gene3D G3DSA:3.40.50.720 64 120 8.6E-4 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS16865 2ddf64cd1820536803fb1277f9c281b1 357 Gene3D G3DSA:3.40.50.720 161 247 8.6E-4 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS16865 2ddf64cd1820536803fb1277f9c281b1 357 Pfam PF01548 Transposase 15 160 3.7E-16 T 06-07-2017 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 BWK49_RS16865 2ddf64cd1820536803fb1277f9c281b1 357 Pfam PF02371 Transposase IS116/IS110/IS902 family 235 316 1.6E-17 T 06-07-2017 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 BWK49_RS20530 2ddf64cd1820536803fb1277f9c281b1 357 Gene3D G3DSA:3.40.50.720 64 120 8.6E-4 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS20530 2ddf64cd1820536803fb1277f9c281b1 357 Gene3D G3DSA:3.40.50.720 161 247 8.6E-4 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS20530 2ddf64cd1820536803fb1277f9c281b1 357 Pfam PF01548 Transposase 15 160 3.7E-16 T 06-07-2017 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 BWK49_RS20530 2ddf64cd1820536803fb1277f9c281b1 357 Pfam PF02371 Transposase IS116/IS110/IS902 family 235 316 1.6E-17 T 06-07-2017 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 BWK49_RS05255 2ddf64cd1820536803fb1277f9c281b1 357 Gene3D G3DSA:3.40.50.720 64 120 8.6E-4 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS05255 2ddf64cd1820536803fb1277f9c281b1 357 Gene3D G3DSA:3.40.50.720 161 247 8.6E-4 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS05255 2ddf64cd1820536803fb1277f9c281b1 357 Pfam PF01548 Transposase 15 160 3.7E-16 T 06-07-2017 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 BWK49_RS05255 2ddf64cd1820536803fb1277f9c281b1 357 Pfam PF02371 Transposase IS116/IS110/IS902 family 235 316 1.6E-17 T 06-07-2017 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 BWK49_RS18290 bbfe8f28096b10ac0a0985c103e3e912 423 Pfam PF07859 alpha/beta hydrolase fold 184 392 4.4E-19 T 06-07-2017 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 BWK49_RS18290 bbfe8f28096b10ac0a0985c103e3e912 423 SUPERFAMILY SSF53474 148 412 1.42E-48 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS18290 bbfe8f28096b10ac0a0985c103e3e912 423 Gene3D G3DSA:3.40.50.1820 149 411 7.9E-62 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS12395 12a422dbe0ae2a09bd0afc1a8955339b 361 TIGRFAM TIGR03451 mycoS_dep_FDH: S-(hydroxymethyl)mycothiol dehydrogenase 4 361 3.0E-208 T 06-07-2017 IPR017816 S-(hydroxymethyl)mycothiol dehydrogenase KEGG: 00072+1.1.1.30|KEGG: 00650+1.1.1.30 BWK49_RS12395 12a422dbe0ae2a09bd0afc1a8955339b 361 Gene3D G3DSA:3.90.180.10 2 182 3.3E-54 T 06-07-2017 IPR011032 GroES-like BWK49_RS12395 12a422dbe0ae2a09bd0afc1a8955339b 361 SUPERFAMILY SSF50129 4 186 1.67E-52 T 06-07-2017 IPR011032 GroES-like BWK49_RS12395 12a422dbe0ae2a09bd0afc1a8955339b 361 SUPERFAMILY SSF50129 311 360 1.18E-6 T 06-07-2017 IPR011032 GroES-like BWK49_RS12395 12a422dbe0ae2a09bd0afc1a8955339b 361 SMART SM00829 14 361 0.0087 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 BWK49_RS12395 12a422dbe0ae2a09bd0afc1a8955339b 361 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 06-07-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 BWK49_RS12395 12a422dbe0ae2a09bd0afc1a8955339b 361 Pfam PF00107 Zinc-binding dehydrogenase 190 321 1.9E-28 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 BWK49_RS12395 12a422dbe0ae2a09bd0afc1a8955339b 361 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 147 4.2E-26 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 BWK49_RS12395 12a422dbe0ae2a09bd0afc1a8955339b 361 Gene3D G3DSA:3.40.50.720 183 302 8.9E-41 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS12395 12a422dbe0ae2a09bd0afc1a8955339b 361 SUPERFAMILY SSF51735 153 326 5.23E-43 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS02510 b4d8f07d7ab46c703734bbe74954791e 409 Pfam PF08353 Domain of unknown function (DUF1727) 299 398 1.4E-23 T 06-07-2017 IPR013564 Domain of unknown function DUF1727 BWK49_RS02510 b4d8f07d7ab46c703734bbe74954791e 409 Gene3D G3DSA:3.40.1190.10 43 279 4.1E-41 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 BWK49_RS02510 b4d8f07d7ab46c703734bbe74954791e 409 Pfam PF08245 Mur ligase middle domain 56 261 4.6E-15 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 BWK49_RS02510 b4d8f07d7ab46c703734bbe74954791e 409 SUPERFAMILY SSF53623 216 277 3.09E-32 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 BWK49_RS02510 b4d8f07d7ab46c703734bbe74954791e 409 SUPERFAMILY SSF53623 44 189 3.09E-32 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 BWK49_RS19015 3e25c1bd03fc2803d54bfeffa8495630 161 Gene3D G3DSA:1.20.120.520 27 137 1.6E-10 T 06-07-2017 BWK49_RS19015 3e25c1bd03fc2803d54bfeffa8495630 161 Pfam PF01814 Hemerythrin HHE cation binding domain 3 116 9.5E-15 T 06-07-2017 IPR012312 Haemerythrin-like Reactome: R-HSA-390471 BWK49_RS25525 2eb45cefb52e8a7d504954dfa695d787 507 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 295 306 - T 06-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 BWK49_RS25525 2eb45cefb52e8a7d504954dfa695d787 507 SUPERFAMILY SSF53720 14 499 4.71E-161 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 BWK49_RS25525 2eb45cefb52e8a7d504954dfa695d787 507 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 262 269 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 BWK49_RS25525 2eb45cefb52e8a7d504954dfa695d787 507 Gene3D G3DSA:3.40.605.10 19 270 2.0E-93 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 BWK49_RS25525 2eb45cefb52e8a7d504954dfa695d787 507 Gene3D G3DSA:3.40.309.10 271 470 1.0E-57 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 BWK49_RS25525 2eb45cefb52e8a7d504954dfa695d787 507 Pfam PF00171 Aldehyde dehydrogenase family 28 494 2.5E-162 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 BWK49_RS24895 cb83cd13d0417da4259c90235cf2ffb7 507 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 300 311 - T 06-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 BWK49_RS24895 cb83cd13d0417da4259c90235cf2ffb7 507 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 272 279 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 BWK49_RS24895 cb83cd13d0417da4259c90235cf2ffb7 507 Gene3D G3DSA:3.40.309.10 286 471 1.8E-65 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 BWK49_RS24895 cb83cd13d0417da4259c90235cf2ffb7 507 SUPERFAMILY SSF53720 22 496 1.44E-149 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 BWK49_RS24895 cb83cd13d0417da4259c90235cf2ffb7 507 Gene3D G3DSA:3.40.605.10 30 285 4.9E-73 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 BWK49_RS24895 cb83cd13d0417da4259c90235cf2ffb7 507 Pfam PF00171 Aldehyde dehydrogenase family 39 496 1.1E-150 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 BWK49_RS00910 101c860275757c390fb5cdaf1be27522 318 SUPERFAMILY SSF52540 62 271 1.27E-22 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS00910 101c860275757c390fb5cdaf1be27522 318 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 65 265 4.4E-8 T 06-07-2017 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain BWK49_RS00910 101c860275757c390fb5cdaf1be27522 318 Gene3D G3DSA:3.40.50.300 62 270 1.2E-20 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS09360 bbfc428ecde5ebb74b6f0c515656de8c 477 SUPERFAMILY SSF53720 3 433 1.44E-106 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 BWK49_RS09360 bbfc428ecde5ebb74b6f0c515656de8c 477 PIRSF PIRSF036492 1 475 4.8E-141 T 06-07-2017 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0004030|GO:0006081|GO:0055114 BWK49_RS09360 bbfc428ecde5ebb74b6f0c515656de8c 477 Gene3D G3DSA:3.40.309.10 218 409 8.0E-49 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 BWK49_RS09360 bbfc428ecde5ebb74b6f0c515656de8c 477 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 204 211 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 BWK49_RS09360 bbfc428ecde5ebb74b6f0c515656de8c 477 Gene3D G3DSA:3.40.605.10 16 217 8.6E-46 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 BWK49_RS09360 bbfc428ecde5ebb74b6f0c515656de8c 477 Pfam PF00171 Aldehyde dehydrogenase family 17 432 1.8E-84 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 BWK49_RS23865 7dad2903f8888d22041dd0e4643e84b4 391 Hamap MF_01201 Alanine racemase. 14 384 32.087 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 BWK49_RS23865 7dad2903f8888d22041dd0e4643e84b4 391 Gene3D G3DSA:3.20.20.10 23 232 3.6E-68 T 06-07-2017 IPR029066 PLP-binding barrel BWK49_RS23865 7dad2903f8888d22041dd0e4643e84b4 391 PRINTS PR00992 Alanine racemase signature 309 326 3.5E-71 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 BWK49_RS23865 7dad2903f8888d22041dd0e4643e84b4 391 PRINTS PR00992 Alanine racemase signature 173 184 3.5E-71 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 BWK49_RS23865 7dad2903f8888d22041dd0e4643e84b4 391 PRINTS PR00992 Alanine racemase signature 366 379 3.5E-71 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 BWK49_RS23865 7dad2903f8888d22041dd0e4643e84b4 391 PRINTS PR00992 Alanine racemase signature 75 93 3.5E-71 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 BWK49_RS23865 7dad2903f8888d22041dd0e4643e84b4 391 PRINTS PR00992 Alanine racemase signature 216 243 3.5E-71 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 BWK49_RS23865 7dad2903f8888d22041dd0e4643e84b4 391 PRINTS PR00992 Alanine racemase signature 136 148 3.5E-71 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 BWK49_RS23865 7dad2903f8888d22041dd0e4643e84b4 391 PRINTS PR00992 Alanine racemase signature 271 286 3.5E-71 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 BWK49_RS23865 7dad2903f8888d22041dd0e4643e84b4 391 PRINTS PR00992 Alanine racemase signature 39 55 3.5E-71 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 BWK49_RS23865 7dad2903f8888d22041dd0e4643e84b4 391 PRINTS PR00992 Alanine racemase signature 288 303 3.5E-71 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 BWK49_RS23865 7dad2903f8888d22041dd0e4643e84b4 391 Gene3D G3DSA:2.40.37.10 233 386 1.7E-56 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 BWK49_RS23865 7dad2903f8888d22041dd0e4643e84b4 391 SMART SM01005 255 384 2.7E-67 T 06-07-2017 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 BWK49_RS23865 7dad2903f8888d22041dd0e4643e84b4 391 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 44 54 - T 06-07-2017 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 BWK49_RS23865 7dad2903f8888d22041dd0e4643e84b4 391 Pfam PF00842 Alanine racemase, C-terminal domain 255 383 8.5E-39 T 06-07-2017 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 BWK49_RS23865 7dad2903f8888d22041dd0e4643e84b4 391 SUPERFAMILY SSF50621 249 385 4.53E-47 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 BWK49_RS23865 7dad2903f8888d22041dd0e4643e84b4 391 SUPERFAMILY SSF51419 21 256 1.96E-58 T 06-07-2017 IPR029066 PLP-binding barrel BWK49_RS23865 7dad2903f8888d22041dd0e4643e84b4 391 Pfam PF01168 Alanine racemase, N-terminal domain 21 243 7.6E-65 T 06-07-2017 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 BWK49_RS23865 7dad2903f8888d22041dd0e4643e84b4 391 TIGRFAM TIGR00492 alr: alanine racemase 19 383 1.1E-93 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 BWK49_RS12175 158b939b41aed6191ebc5e7194e65eaa 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 57 2.2E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS12175 158b939b41aed6191ebc5e7194e65eaa 210 SUPERFAMILY SSF46689 3 77 6.98E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS12175 158b939b41aed6191ebc5e7194e65eaa 210 Gene3D G3DSA:1.10.357.10 55 198 2.6E-23 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS12175 158b939b41aed6191ebc5e7194e65eaa 210 Gene3D G3DSA:1.10.10.60 2 53 2.3E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS09950 e1d2b6971c97532e270d8093b2038bdd 198 Hamap MF_00316 Molybdenum cofactor guanylyltransferase [mobA]. 6 193 21.889 T 06-07-2017 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 MetaCyc: PWY-5964|MetaCyc: PWY-7639 BWK49_RS09950 e1d2b6971c97532e270d8093b2038bdd 198 SUPERFAMILY SSF53448 8 190 6.17E-22 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases BWK49_RS09950 e1d2b6971c97532e270d8093b2038bdd 198 Pfam PF12804 MobA-like NTP transferase domain 10 167 3.9E-26 T 06-07-2017 IPR025877 MobA-like NTP transferase BWK49_RS09950 e1d2b6971c97532e270d8093b2038bdd 198 Gene3D G3DSA:3.90.550.10 7 195 1.6E-40 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases BWK49_RS19830 6be4697e9e5994c1b2c58a29f9c8f143 161 SUPERFAMILY SSF55961 14 159 5.5E-32 T 06-07-2017 BWK49_RS19830 6be4697e9e5994c1b2c58a29f9c8f143 161 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 22 159 2.2E-17 T 06-07-2017 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 BWK49_RS19830 6be4697e9e5994c1b2c58a29f9c8f143 161 Gene3D G3DSA:3.30.530.20 8 160 1.1E-28 T 06-07-2017 IPR023393 START-like domain BWK49_RS24970 038b4f9126074dc4b948510aa1679312 195 Gene3D G3DSA:1.10.357.10 53 191 1.1E-24 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS24970 038b4f9126074dc4b948510aa1679312 195 SUPERFAMILY SSF48498 78 191 4.92E-15 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS24970 038b4f9126074dc4b948510aa1679312 195 Gene3D G3DSA:1.10.10.60 15 52 9.6E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS24970 038b4f9126074dc4b948510aa1679312 195 SUPERFAMILY SSF46689 14 83 1.07E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS24970 038b4f9126074dc4b948510aa1679312 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 56 4.6E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS06045 bbb423acc9221cfc38040471734da17e 391 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 235 386 4.4E-15 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS06045 bbb423acc9221cfc38040471734da17e 391 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 127 222 1.9E-21 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 BWK49_RS06045 bbb423acc9221cfc38040471734da17e 391 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 123 4.1E-15 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS06045 bbb423acc9221cfc38040471734da17e 391 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 129 141 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 BWK49_RS06045 bbb423acc9221cfc38040471734da17e 391 Gene3D G3DSA:2.40.110.10 127 223 5.1E-38 T 06-07-2017 BWK49_RS06045 bbb423acc9221cfc38040471734da17e 391 SUPERFAMILY SSF47203 235 388 2.74E-16 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS06045 bbb423acc9221cfc38040471734da17e 391 Gene3D G3DSA:1.20.140.10 224 390 6.6E-29 T 06-07-2017 BWK49_RS06045 bbb423acc9221cfc38040471734da17e 391 SUPERFAMILY SSF56645 3 248 1.11E-70 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS06045 bbb423acc9221cfc38040471734da17e 391 Gene3D G3DSA:1.10.540.10 5 124 3.8E-20 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS03805 9eadbba7f74a06993d05e27673f565e2 208 SUPERFAMILY SSF46689 20 85 3.44E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS03805 9eadbba7f74a06993d05e27673f565e2 208 Gene3D G3DSA:1.10.357.10 18 195 3.2E-23 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS03805 9eadbba7f74a06993d05e27673f565e2 208 Pfam PF00440 Bacterial regulatory proteins, tetR family 33 78 5.2E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS03805 9eadbba7f74a06993d05e27673f565e2 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 53 76 3.2E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS03805 9eadbba7f74a06993d05e27673f565e2 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 45 3.2E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS03805 9eadbba7f74a06993d05e27673f565e2 208 ProSitePatterns PS01081 TetR-type HTH domain signature. 44 75 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site BWK49_RS14765 2fa7dba08be7fa8281a7245678bb6dfd 440 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 374 383 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 BWK49_RS14765 2fa7dba08be7fa8281a7245678bb6dfd 440 Gene3D G3DSA:1.10.630.10 33 432 7.9E-103 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS14765 2fa7dba08be7fa8281a7245678bb6dfd 440 SUPERFAMILY SSF48264 39 418 3.67E-84 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS14765 2fa7dba08be7fa8281a7245678bb6dfd 440 PRINTS PR00359 B-class P450 signature 114 125 3.6E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS14765 2fa7dba08be7fa8281a7245678bb6dfd 440 PRINTS PR00359 B-class P450 signature 381 392 3.6E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS14765 2fa7dba08be7fa8281a7245678bb6dfd 440 PRINTS PR00359 B-class P450 signature 178 193 3.6E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS14765 2fa7dba08be7fa8281a7245678bb6dfd 440 PRINTS PR00359 B-class P450 signature 161 177 3.6E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS14765 2fa7dba08be7fa8281a7245678bb6dfd 440 PRINTS PR00359 B-class P450 signature 221 243 3.6E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS14765 2fa7dba08be7fa8281a7245678bb6dfd 440 PRINTS PR00359 B-class P450 signature 305 316 3.6E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS14765 2fa7dba08be7fa8281a7245678bb6dfd 440 PRINTS PR00359 B-class P450 signature 322 349 3.6E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS14765 2fa7dba08be7fa8281a7245678bb6dfd 440 PRINTS PR00359 B-class P450 signature 372 381 3.6E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS14765 2fa7dba08be7fa8281a7245678bb6dfd 440 PRINTS PR00359 B-class P450 signature 350 365 3.6E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS14765 2fa7dba08be7fa8281a7245678bb6dfd 440 Pfam PF00067 Cytochrome P450 305 402 3.7E-22 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS26105 958b202caadc2ad410bbb29f53b61e4e 303 Gene3D G3DSA:2.70.98.10 13 300 1.3E-16 T 06-07-2017 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0003824|GO:0005975|GO:0030246 BWK49_RS26105 958b202caadc2ad410bbb29f53b61e4e 303 SUPERFAMILY SSF74650 3 300 3.14E-42 T 06-07-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 BWK49_RS26105 958b202caadc2ad410bbb29f53b61e4e 303 Pfam PF01263 Aldose 1-epimerase 26 281 1.9E-23 T 06-07-2017 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 BWK49_RS19025 f033bb90cc7eb7a03974ec0eee495b0b 449 SUPERFAMILY SSF50022 14 159 4.45E-45 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS19025 f033bb90cc7eb7a03974ec0eee495b0b 449 ProSitePatterns PS00570 Bacterial ring hydroxylating dioxygenases alpha-subunit signature. 85 108 - T 06-07-2017 IPR015881 Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site GO:0005506|GO:0016705|GO:0051537|GO:0055114 BWK49_RS19025 f033bb90cc7eb7a03974ec0eee495b0b 449 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 99 119 1.1E-40 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS19025 f033bb90cc7eb7a03974ec0eee495b0b 449 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 57 72 1.1E-40 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS19025 f033bb90cc7eb7a03974ec0eee495b0b 449 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 78 98 1.1E-40 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS19025 f033bb90cc7eb7a03974ec0eee495b0b 449 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 144 170 1.1E-40 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS19025 f033bb90cc7eb7a03974ec0eee495b0b 449 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 27 52 1.1E-40 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS19025 f033bb90cc7eb7a03974ec0eee495b0b 449 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 184 206 1.1E-40 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS19025 f033bb90cc7eb7a03974ec0eee495b0b 449 Gene3D G3DSA:2.102.10.10 33 125 6.3E-18 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS19025 f033bb90cc7eb7a03974ec0eee495b0b 449 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 165 445 7.6E-19 T 06-07-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 BWK49_RS19025 f033bb90cc7eb7a03974ec0eee495b0b 449 Gene3D G3DSA:3.90.380.10 134 447 3.0E-97 T 06-07-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 BWK49_RS19025 f033bb90cc7eb7a03974ec0eee495b0b 449 Pfam PF00355 Rieske [2Fe-2S] domain 43 126 5.4E-20 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS19025 f033bb90cc7eb7a03974ec0eee495b0b 449 SUPERFAMILY SSF55961 160 446 3.38E-49 T 06-07-2017 BWK49_RS19325 03cfdab62248d13a80eec66ca0838ddf 163 Gene3D G3DSA:3.10.580.10 25 159 1.7E-14 T 06-07-2017 BWK49_RS19325 03cfdab62248d13a80eec66ca0838ddf 163 SMART SM00116 25 73 0.11 T 06-07-2017 IPR000644 CBS domain BWK49_RS19325 03cfdab62248d13a80eec66ca0838ddf 163 SMART SM00116 114 161 0.0054 T 06-07-2017 IPR000644 CBS domain BWK49_RS19325 03cfdab62248d13a80eec66ca0838ddf 163 SUPERFAMILY SSF54631 15 159 4.27E-17 T 06-07-2017 BWK49_RS19325 03cfdab62248d13a80eec66ca0838ddf 163 Pfam PF00571 CBS domain 114 160 5.8E-6 T 06-07-2017 IPR000644 CBS domain BWK49_RS19325 03cfdab62248d13a80eec66ca0838ddf 163 Pfam PF00571 CBS domain 23 73 5.7E-4 T 06-07-2017 IPR000644 CBS domain BWK49_RS25965 5ca1b84128d5a9bdda0a9efe8b3408fc 223 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 50 73 1.7E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS25965 5ca1b84128d5a9bdda0a9efe8b3408fc 223 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 42 1.7E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS25965 5ca1b84128d5a9bdda0a9efe8b3408fc 223 SUPERFAMILY SSF46689 19 95 2.36E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS25965 5ca1b84128d5a9bdda0a9efe8b3408fc 223 ProSitePatterns PS01081 TetR-type HTH domain signature. 41 72 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site BWK49_RS25965 5ca1b84128d5a9bdda0a9efe8b3408fc 223 Pfam PF00440 Bacterial regulatory proteins, tetR family 30 74 9.4E-16 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS25965 5ca1b84128d5a9bdda0a9efe8b3408fc 223 SUPERFAMILY SSF48498 97 212 1.01E-14 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS25965 5ca1b84128d5a9bdda0a9efe8b3408fc 223 Gene3D G3DSA:1.10.10.60 18 75 4.9E-19 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS25965 5ca1b84128d5a9bdda0a9efe8b3408fc 223 Gene3D G3DSA:1.10.357.10 76 212 2.8E-22 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS28030 e756b50be5a0eed59e74f50b820d6f13 386 Pfam PF13469 Sulfotransferase family 82 323 2.2E-39 T 06-07-2017 BWK49_RS28030 e756b50be5a0eed59e74f50b820d6f13 386 Gene3D G3DSA:3.40.50.300 195 340 4.9E-10 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS28030 e756b50be5a0eed59e74f50b820d6f13 386 Gene3D G3DSA:3.40.50.300 83 137 4.9E-10 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS28030 e756b50be5a0eed59e74f50b820d6f13 386 SUPERFAMILY SSF52540 185 335 4.18E-29 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS28030 e756b50be5a0eed59e74f50b820d6f13 386 SUPERFAMILY SSF52540 77 117 4.18E-29 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS10790 0a979e55ca3421955aaf17106f4091c7 210 SUPERFAMILY SSF46689 11 95 1.18E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS10790 0a979e55ca3421955aaf17106f4091c7 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 69 5.3E-13 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS10790 0a979e55ca3421955aaf17106f4091c7 210 Gene3D G3DSA:1.10.357.10 11 198 9.2E-33 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS17000 ee06751508eecbab68a47aea485e6b55 355 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 19 250 8.7E-49 T 06-07-2017 IPR018713 Domain of unknown function DUF2236 BWK49_RS15440 37366d4dc4746924d4876deab21fe20f 181 Gene3D G3DSA:3.40.50.150 34 138 2.9E-20 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS15440 37366d4dc4746924d4876deab21fe20f 181 SUPERFAMILY SSF53335 5 162 3.04E-24 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS15440 37366d4dc4746924d4876deab21fe20f 181 Pfam PF13649 Methyltransferase domain 44 132 3.9E-11 T 06-07-2017 BWK49_RS26215 ba7d48f77635fc328b1cf746bb9d9119 441 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 179 2.5E-59 T 06-07-2017 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 BWK49_RS26215 ba7d48f77635fc328b1cf746bb9d9119 441 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 322 422 9.0E-28 T 06-07-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 BWK49_RS26215 ba7d48f77635fc328b1cf746bb9d9119 441 PIRSF PIRSF000124 1 438 1.5E-119 T 06-07-2017 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 BWK49_RS26215 ba7d48f77635fc328b1cf746bb9d9119 441 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 419 2.3E-132 T 06-07-2017 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 BWK49_RS26215 ba7d48f77635fc328b1cf746bb9d9119 441 Gene3D G3DSA:3.40.50.720 235 439 1.9E-68 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS26215 ba7d48f77635fc328b1cf746bb9d9119 441 Gene3D G3DSA:1.20.5.100 208 233 3.2E-16 T 06-07-2017 BWK49_RS26215 ba7d48f77635fc328b1cf746bb9d9119 441 Gene3D G3DSA:3.40.50.720 1 207 7.9E-67 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS26215 ba7d48f77635fc328b1cf746bb9d9119 441 SUPERFAMILY SSF51735 1 194 6.81E-46 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS26215 ba7d48f77635fc328b1cf746bb9d9119 441 SUPERFAMILY SSF48179 204 303 4.08E-27 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 BWK49_RS26215 ba7d48f77635fc328b1cf746bb9d9119 441 SUPERFAMILY SSF52413 311 434 1.44E-33 T 06-07-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 BWK49_RS26215 ba7d48f77635fc328b1cf746bb9d9119 441 SMART SM00984 322 423 7.1E-44 T 06-07-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 BWK49_RS26215 ba7d48f77635fc328b1cf746bb9d9119 441 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 204 298 7.3E-31 T 06-07-2017 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 BWK49_RS26215 ba7d48f77635fc328b1cf746bb9d9119 441 PIRSF PIRSF500134 1 440 7.5E-155 T 06-07-2017 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00500+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346 BWK49_RS18215 dd7dd5b4f86e3318c3f53134ba046708 514 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 28 513 4.6E-204 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 BWK49_RS18215 dd7dd5b4f86e3318c3f53134ba046708 514 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 247 264 5.4E-48 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 BWK49_RS18215 dd7dd5b4f86e3318c3f53134ba046708 514 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 171 184 5.4E-48 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 BWK49_RS18215 dd7dd5b4f86e3318c3f53134ba046708 514 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 195 223 5.4E-48 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 BWK49_RS18215 dd7dd5b4f86e3318c3f53134ba046708 514 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 354 380 5.4E-48 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 BWK49_RS18215 dd7dd5b4f86e3318c3f53134ba046708 514 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 265 281 5.4E-48 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 BWK49_RS18215 dd7dd5b4f86e3318c3f53134ba046708 514 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 28 513 89.669 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 BWK49_RS18215 dd7dd5b4f86e3318c3f53134ba046708 514 ProSitePatterns PS00069 Glucose-6-phosphate dehydrogenase active site. 205 211 - T 06-07-2017 IPR019796 Glucose-6-phosphate dehydrogenase, active site GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 BWK49_RS18215 dd7dd5b4f86e3318c3f53134ba046708 514 Gene3D G3DSA:3.30.360.10 215 512 6.2E-116 T 06-07-2017 BWK49_RS18215 dd7dd5b4f86e3318c3f53134ba046708 514 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 217 512 9.4E-109 T 06-07-2017 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 BWK49_RS18215 dd7dd5b4f86e3318c3f53134ba046708 514 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 32 215 1.0E-61 T 06-07-2017 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 BWK49_RS18215 dd7dd5b4f86e3318c3f53134ba046708 514 Gene3D G3DSA:3.40.50.720 27 214 1.1E-68 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS18215 dd7dd5b4f86e3318c3f53134ba046708 514 SUPERFAMILY SSF51735 15 218 5.91E-62 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS18215 dd7dd5b4f86e3318c3f53134ba046708 514 PIRSF PIRSF000110 2 514 1.1E-177 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 BWK49_RS18215 dd7dd5b4f86e3318c3f53134ba046708 514 SUPERFAMILY SSF55347 205 512 2.26E-109 T 06-07-2017 BWK49_RS16555 95b06200735948970f912879014c12ed 92 SUPERFAMILY SSF47413 18 82 2.82E-16 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 BWK49_RS16555 95b06200735948970f912879014c12ed 92 Pfam PF01381 Helix-turn-helix 27 81 2.2E-13 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 BWK49_RS16555 95b06200735948970f912879014c12ed 92 SMART SM00530 26 81 3.2E-13 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 BWK49_RS16555 95b06200735948970f912879014c12ed 92 Gene3D G3DSA:1.10.260.40 16 84 4.7E-18 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 BWK49_RS28295 c17055ca22a98684b36fff76818bbabb 480 SUPERFAMILY SSF81301 21 163 3.6E-35 T 06-07-2017 BWK49_RS28295 c17055ca22a98684b36fff76818bbabb 480 Gene3D G3DSA:3.30.460.10 20 162 1.2E-40 T 06-07-2017 BWK49_RS28295 c17055ca22a98684b36fff76818bbabb 480 SUPERFAMILY SSF81891 165 474 2.75E-64 T 06-07-2017 BWK49_RS28295 c17055ca22a98684b36fff76818bbabb 480 TIGRFAM TIGR02692 tRNA_CCA_actino: CCA tRNA nucleotidyltransferase 11 475 7.5E-255 T 06-07-2017 IPR014065 tRNA adenylyltransferase BWK49_RS28295 c17055ca22a98684b36fff76818bbabb 480 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 193 252 4.8E-17 T 06-07-2017 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 BWK49_RS28295 c17055ca22a98684b36fff76818bbabb 480 Pfam PF01966 HD domain 268 388 1.7E-15 T 06-07-2017 IPR006674 HD domain BWK49_RS28295 c17055ca22a98684b36fff76818bbabb 480 SMART SM00471 264 419 9.6E-7 T 06-07-2017 IPR003607 HD/PDEase domain BWK49_RS28295 c17055ca22a98684b36fff76818bbabb 480 TIGRFAM TIGR00277 HDIG: HDIG domain 265 345 5.1E-20 T 06-07-2017 IPR006675 HDIG domain BWK49_RS28295 c17055ca22a98684b36fff76818bbabb 480 Gene3D G3DSA:1.10.3090.10 420 442 5.7E-53 T 06-07-2017 BWK49_RS28295 c17055ca22a98684b36fff76818bbabb 480 Gene3D G3DSA:1.10.3090.10 164 352 5.7E-53 T 06-07-2017 BWK49_RS28295 c17055ca22a98684b36fff76818bbabb 480 Pfam PF01743 Poly A polymerase head domain 39 165 1.3E-35 T 06-07-2017 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 BWK49_RS13360 9afc89fc8f7387a6cd18c2f74c4cdb0d 456 PIRSF PIRSF000350 1 445 3.4E-89 T 06-07-2017 BWK49_RS13360 9afc89fc8f7387a6cd18c2f74c4cdb0d 456 Gene3D G3DSA:3.30.390.30 327 451 1.3E-31 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 BWK49_RS13360 9afc89fc8f7387a6cd18c2f74c4cdb0d 456 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 39 49 - T 06-07-2017 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 BWK49_RS13360 9afc89fc8f7387a6cd18c2f74c4cdb0d 456 Gene3D G3DSA:3.50.50.60 143 326 2.8E-49 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS13360 9afc89fc8f7387a6cd18c2f74c4cdb0d 456 SUPERFAMILY SSF51905 3 313 6.76E-52 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS13360 9afc89fc8f7387a6cd18c2f74c4cdb0d 456 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 309 1.4E-57 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS13360 9afc89fc8f7387a6cd18c2f74c4cdb0d 456 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 285 307 1.8E-22 T 06-07-2017 BWK49_RS13360 9afc89fc8f7387a6cd18c2f74c4cdb0d 456 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 1.8E-22 T 06-07-2017 BWK49_RS13360 9afc89fc8f7387a6cd18c2f74c4cdb0d 456 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 132 150 1.8E-22 T 06-07-2017 BWK49_RS13360 9afc89fc8f7387a6cd18c2f74c4cdb0d 456 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 171 189 1.8E-22 T 06-07-2017 BWK49_RS13360 9afc89fc8f7387a6cd18c2f74c4cdb0d 456 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 256 272 1.8E-22 T 06-07-2017 BWK49_RS13360 9afc89fc8f7387a6cd18c2f74c4cdb0d 456 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 401 416 7.8E-42 T 06-07-2017 BWK49_RS13360 9afc89fc8f7387a6cd18c2f74c4cdb0d 456 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 257 271 7.8E-42 T 06-07-2017 BWK49_RS13360 9afc89fc8f7387a6cd18c2f74c4cdb0d 456 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 300 307 7.8E-42 T 06-07-2017 BWK49_RS13360 9afc89fc8f7387a6cd18c2f74c4cdb0d 456 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 336 357 7.8E-42 T 06-07-2017 BWK49_RS13360 9afc89fc8f7387a6cd18c2f74c4cdb0d 456 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 7.8E-42 T 06-07-2017 BWK49_RS13360 9afc89fc8f7387a6cd18c2f74c4cdb0d 456 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 7.8E-42 T 06-07-2017 BWK49_RS13360 9afc89fc8f7387a6cd18c2f74c4cdb0d 456 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 171 196 7.8E-42 T 06-07-2017 BWK49_RS13360 9afc89fc8f7387a6cd18c2f74c4cdb0d 456 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 423 443 7.8E-42 T 06-07-2017 BWK49_RS13360 9afc89fc8f7387a6cd18c2f74c4cdb0d 456 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 343 446 1.2E-22 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 BWK49_RS13360 9afc89fc8f7387a6cd18c2f74c4cdb0d 456 SUPERFAMILY SSF55424 340 451 1.15E-29 T 06-07-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 BWK49_RS13360 9afc89fc8f7387a6cd18c2f74c4cdb0d 456 Gene3D G3DSA:3.50.50.60 3 142 1.3E-34 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS23090 ab2622beafcb425ed5df224d60ab17a6 267 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 BWK49_RS23090 ab2622beafcb425ed5df224d60ab17a6 267 Pfam PF00005 ABC transporter 16 171 4.6E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 BWK49_RS23090 ab2622beafcb425ed5df224d60ab17a6 267 Gene3D G3DSA:3.40.50.300 5 240 5.5E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS23090 ab2622beafcb425ed5df224d60ab17a6 267 SMART SM00382 25 218 2.7E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS23090 ab2622beafcb425ed5df224d60ab17a6 267 SUPERFAMILY SSF52540 3 235 2.33E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS09620 6ac70c855f870209b9347f364af8c518 130 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 82 128 8.0E-4 T 06-07-2017 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 BWK49_RS09620 6ac70c855f870209b9347f364af8c518 130 SUPERFAMILY SSF56214 3 128 1.31E-22 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 BWK49_RS09620 6ac70c855f870209b9347f364af8c518 130 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 3 129 5.9E-39 T 06-07-2017 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 BWK49_RS09620 6ac70c855f870209b9347f364af8c518 130 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 4 129 21.005 T 06-07-2017 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 BWK49_RS09620 6ac70c855f870209b9347f364af8c518 130 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 5 104 8.6E-19 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 BWK49_RS09620 6ac70c855f870209b9347f364af8c518 130 Gene3D G3DSA:3.90.470.20 3 128 1.5E-43 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 BWK49_RS19070 fc47b642beca1d3134ac0a0fe43048bf 361 SUPERFAMILY SSF55931 2 357 6.96E-85 T 06-07-2017 BWK49_RS19070 fc47b642beca1d3134ac0a0fe43048bf 361 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 7 280 6.8E-48 T 06-07-2017 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 BWK49_RS19070 fc47b642beca1d3134ac0a0fe43048bf 361 Hamap MF_01609 Glutamate--cysteine ligase [gshA]. 1 361 79.023 T 06-07-2017 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 BWK49_RS19070 fc47b642beca1d3134ac0a0fe43048bf 361 TIGRFAM TIGR02050 gshA_cyan_rel: carboxylate-amine ligase, YbdK family 6 284 6.2E-76 T 06-07-2017 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 BWK49_RS16420 b585fc266dc7d1de6e47311c50ba58ce 185 Gene3D G3DSA:3.40.630.30 20 185 9.1E-51 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase BWK49_RS16420 b585fc266dc7d1de6e47311c50ba58ce 185 SUPERFAMILY SSF55729 20 185 6.82E-44 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase BWK49_RS16420 b585fc266dc7d1de6e47311c50ba58ce 185 Pfam PF13523 Acetyltransferase (GNAT) domain 28 172 4.7E-46 T 06-07-2017 BWK49_RS16420 b585fc266dc7d1de6e47311c50ba58ce 185 SMART SM01006 25 72 1.0E-15 T 06-07-2017 IPR019432 Siderophore biosynthesis protein, conserved domain BWK49_RS20810 68b1eba3125a520f44b5cd085ffee249 276 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 74 85 4.1E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS20810 68b1eba3125a520f44b5cd085ffee249 276 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 147 166 4.1E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS20810 68b1eba3125a520f44b5cd085ffee249 276 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 127 135 4.1E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS20810 68b1eba3125a520f44b5cd085ffee249 276 Pfam PF00106 short chain dehydrogenase 5 189 4.5E-55 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS20810 68b1eba3125a520f44b5cd085ffee249 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 2.5E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS20810 68b1eba3125a520f44b5cd085ffee249 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 185 2.5E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS20810 68b1eba3125a520f44b5cd085ffee249 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 137 2.5E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS20810 68b1eba3125a520f44b5cd085ffee249 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 2.5E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS20810 68b1eba3125a520f44b5cd085ffee249 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 2.5E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS20810 68b1eba3125a520f44b5cd085ffee249 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 166 2.5E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS20810 68b1eba3125a520f44b5cd085ffee249 276 SUPERFAMILY SSF51735 3 244 3.75E-69 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS20810 68b1eba3125a520f44b5cd085ffee249 276 Gene3D G3DSA:3.40.50.720 4 246 1.2E-74 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS20810 68b1eba3125a520f44b5cd085ffee249 276 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 134 162 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS05130 c9193b2bd3d34ec3725add80b3c73bce 60 SUPERFAMILY SSF46955 1 58 8.24E-6 T 06-07-2017 IPR009061 Putative DNA-binding domain BWK49_RS25880 05aec0b4231e00f6e4675c2ff5c9649a 340 Gene3D G3DSA:3.30.9.10 193 294 1.5E-29 T 06-07-2017 BWK49_RS25880 05aec0b4231e00f6e4675c2ff5c9649a 340 TIGRFAM TIGR02352 thiamin_ThiO: glycine oxidase ThiO 11 333 1.7E-103 T 06-07-2017 IPR012727 Glycine oxidase ThiO GO:0016491|GO:0050660 BWK49_RS25880 05aec0b4231e00f6e4675c2ff5c9649a 340 Gene3D G3DSA:3.50.50.60 295 332 1.1E-23 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS25880 05aec0b4231e00f6e4675c2ff5c9649a 340 Gene3D G3DSA:3.50.50.60 140 192 1.1E-23 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS25880 05aec0b4231e00f6e4675c2ff5c9649a 340 Gene3D G3DSA:3.50.50.60 11 86 1.1E-23 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS25880 05aec0b4231e00f6e4675c2ff5c9649a 340 SUPERFAMILY SSF51905 11 268 2.33E-25 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS25880 05aec0b4231e00f6e4675c2ff5c9649a 340 Pfam PF01266 FAD dependent oxidoreductase 10 330 4.4E-43 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 BWK49_RS10915 eccef8dc395b89a6042b3f6c03daeee6 150 SUPERFAMILY SSF54637 10 136 1.86E-18 T 06-07-2017 IPR029069 HotDog domain BWK49_RS10915 eccef8dc395b89a6042b3f6c03daeee6 150 Gene3D G3DSA:3.10.129.10 9 136 3.5E-19 T 06-07-2017 IPR029069 HotDog domain BWK49_RS10915 eccef8dc395b89a6042b3f6c03daeee6 150 Pfam PF01575 MaoC like domain 19 126 5.7E-8 T 06-07-2017 IPR002539 MaoC-like domain BWK49_RS20115 cbf04ef784add35356c747b41adf6ad6 185 SUPERFAMILY SSF55194 3 184 9.94E-67 T 06-07-2017 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 BWK49_RS20115 cbf04ef784add35356c747b41adf6ad6 185 TIGRFAM TIGR00496 frr: ribosome recycling factor 10 185 1.9E-65 T 06-07-2017 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 BWK49_RS20115 cbf04ef784add35356c747b41adf6ad6 185 Pfam PF01765 Ribosome recycling factor 21 183 4.1E-59 T 06-07-2017 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 BWK49_RS20115 cbf04ef784add35356c747b41adf6ad6 185 Hamap MF_00040 Ribosome-recycling factor [frr]. 3 185 26.099 T 06-07-2017 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 BWK49_RS20115 cbf04ef784add35356c747b41adf6ad6 185 Gene3D G3DSA:1.10.132.20 66 185 1.2E-40 T 06-07-2017 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 BWK49_RS06895 8f8415182c53930b2ff08b26425980bd 755 TIGRFAM TIGR02778 ligD_pol: DNA ligase D, polymerase domain 9 264 7.9E-90 T 06-07-2017 IPR014145 DNA ligase D, polymerase domain BWK49_RS06895 8f8415182c53930b2ff08b26425980bd 755 SUPERFAMILY SSF56091 451 634 1.73E-37 T 06-07-2017 BWK49_RS06895 8f8415182c53930b2ff08b26425980bd 755 Pfam PF01068 ATP dependent DNA ligase domain 456 633 4.1E-28 T 06-07-2017 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 BWK49_RS06895 8f8415182c53930b2ff08b26425980bd 755 SUPERFAMILY SSF50249 636 754 1.66E-26 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS06895 8f8415182c53930b2ff08b26425980bd 755 TIGRFAM TIGR02777 LigD_PE_dom: DNA ligase D, 3'-phosphoesterase domain 300 446 1.9E-57 T 06-07-2017 IPR014144 DNA ligase D, 3'-phosphoesterase domain BWK49_RS06895 8f8415182c53930b2ff08b26425980bd 755 Gene3D G3DSA:3.30.470.30 480 582 2.5E-28 T 06-07-2017 BWK49_RS06895 8f8415182c53930b2ff08b26425980bd 755 Gene3D G3DSA:2.40.50.140 636 755 1.4E-43 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS06895 8f8415182c53930b2ff08b26425980bd 755 TIGRFAM TIGR02779 NHEJ_ligase_lig: DNA ligase D, ligase domain 456 753 2.0E-91 T 06-07-2017 IPR014146 DNA ligase D, ligase domain BWK49_RS06895 8f8415182c53930b2ff08b26425980bd 755 Gene3D G3DSA:3.30.1490.70 451 479 6.3E-22 T 06-07-2017 BWK49_RS06895 8f8415182c53930b2ff08b26425980bd 755 Gene3D G3DSA:3.30.1490.70 590 634 6.3E-22 T 06-07-2017 BWK49_RS06895 8f8415182c53930b2ff08b26425980bd 755 Pfam PF04679 ATP dependent DNA ligase C terminal region 653 747 3.4E-24 T 06-07-2017 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 BWK49_RS06895 8f8415182c53930b2ff08b26425980bd 755 Pfam PF13298 DNA polymerase Ligase (LigD) 332 431 3.1E-37 T 06-07-2017 IPR014144 DNA ligase D, 3'-phosphoesterase domain BWK49_RS23415 4b2027fb8bef569adf99b8826f0e7999 428 Pfam PF00591 Glycosyl transferase family, a/b domain 82 288 1.7E-30 T 06-07-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 BWK49_RS23415 4b2027fb8bef569adf99b8826f0e7999 428 Gene3D G3DSA:3.40.1030.10 75 321 4.8E-102 T 06-07-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 BWK49_RS23415 4b2027fb8bef569adf99b8826f0e7999 428 Gene3D G3DSA:1.20.970.10 7 72 2.8E-26 T 06-07-2017 BWK49_RS23415 4b2027fb8bef569adf99b8826f0e7999 428 Gene3D G3DSA:3.90.1170.30 322 416 1.8E-28 T 06-07-2017 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 BWK49_RS23415 4b2027fb8bef569adf99b8826f0e7999 428 SUPERFAMILY SSF54680 325 426 1.02E-26 T 06-07-2017 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 BWK49_RS23415 4b2027fb8bef569adf99b8826f0e7999 428 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 115 130 - T 06-07-2017 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 BWK49_RS23415 4b2027fb8bef569adf99b8826f0e7999 428 Pfam PF02885 Glycosyl transferase family, helical bundle domain 11 71 1.4E-16 T 06-07-2017 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 BWK49_RS23415 4b2027fb8bef569adf99b8826f0e7999 428 SUPERFAMILY SSF52418 75 321 1.01E-76 T 06-07-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 BWK49_RS23415 4b2027fb8bef569adf99b8826f0e7999 428 SUPERFAMILY SSF47648 7 74 3.92E-19 T 06-07-2017 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 BWK49_RS23415 4b2027fb8bef569adf99b8826f0e7999 428 SMART SM00941 338 412 4.7E-31 T 06-07-2017 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 BWK49_RS23415 4b2027fb8bef569adf99b8826f0e7999 428 TIGRFAM TIGR02644 Y_phosphoryl: pyrimidine-nucleoside phosphorylase 10 410 7.7E-157 T 06-07-2017 IPR018090 Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic GO:0006213|GO:0016154 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181|Reactome: R-HSA-73614|Reactome: R-HSA-73621 BWK49_RS23415 4b2027fb8bef569adf99b8826f0e7999 428 PIRSF PIRSF000478 5 427 8.3E-149 T 06-07-2017 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 BWK49_RS23415 4b2027fb8bef569adf99b8826f0e7999 428 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 340 409 1.7E-21 T 06-07-2017 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 BWK49_RS16015 94887b9094a9863b78b34444062de217 89 Gene3D G3DSA:1.20.5.780 3 82 3.8E-14 T 06-07-2017 BWK49_RS16015 94887b9094a9863b78b34444062de217 89 SUPERFAMILY SSF47598 4 72 1.85E-11 T 06-07-2017 IPR010985 Ribbon-helix-helix GO:0006355 BWK49_RS16015 94887b9094a9863b78b34444062de217 89 Pfam PF08681 Protein of unknown function (DUF1778) 7 81 1.6E-10 T 06-07-2017 IPR014795 Vibrio phage ICP1, Orf50 BWK49_RS13585 1f48c1856127c8f14364828f3e1b1f4d 510 Pfam PF07969 Amidohydrolase family 26 508 2.0E-90 T 06-07-2017 IPR013108 Amidohydrolase 3 BWK49_RS13585 1f48c1856127c8f14364828f3e1b1f4d 510 Gene3D G3DSA:2.30.40.10 426 480 5.4E-4 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 BWK49_RS13585 1f48c1856127c8f14364828f3e1b1f4d 510 Gene3D G3DSA:2.30.40.10 2 64 3.8E-10 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 BWK49_RS13585 1f48c1856127c8f14364828f3e1b1f4d 510 SUPERFAMILY SSF51556 36 92 3.81E-34 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS13585 1f48c1856127c8f14364828f3e1b1f4d 510 SUPERFAMILY SSF51556 158 441 3.81E-34 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS13585 1f48c1856127c8f14364828f3e1b1f4d 510 Gene3D G3DSA:3.20.20.140 164 425 2.3E-30 T 06-07-2017 BWK49_RS13585 1f48c1856127c8f14364828f3e1b1f4d 510 SUPERFAMILY SSF51338 445 468 7.07E-7 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 BWK49_RS13585 1f48c1856127c8f14364828f3e1b1f4d 510 SUPERFAMILY SSF51338 2 37 7.07E-7 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 BWK49_RS18965 ba48544eda1c98ef67b7d7e4a96dfd68 114 SUPERFAMILY SSF51182 3 105 6.85E-13 T 06-07-2017 IPR011051 RmlC-like cupin domain BWK49_RS18965 ba48544eda1c98ef67b7d7e4a96dfd68 114 Gene3D G3DSA:2.60.120.10 23 107 1.4E-13 T 06-07-2017 IPR014710 RmlC-like jelly roll fold BWK49_RS10045 1860f77b8d37c696e527d7e4976b31ce 467 SUPERFAMILY SSF50182 160 224 2.65E-10 T 06-07-2017 IPR010920 LSM domain BWK49_RS10045 1860f77b8d37c696e527d7e4976b31ce 467 Pfam PF00027 Cyclic nucleotide-binding domain 354 438 1.6E-11 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain BWK49_RS10045 1860f77b8d37c696e527d7e4976b31ce 467 SUPERFAMILY SSF51206 337 455 8.98E-19 T 06-07-2017 IPR018490 Cyclic nucleotide-binding-like BWK49_RS10045 1860f77b8d37c696e527d7e4976b31ce 467 SMART SM00100 334 451 5.0E-10 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain BWK49_RS10045 1860f77b8d37c696e527d7e4976b31ce 467 Gene3D G3DSA:2.30.30.60 175 222 3.7E-8 T 06-07-2017 BWK49_RS10045 1860f77b8d37c696e527d7e4976b31ce 467 Pfam PF00924 Mechanosensitive ion channel 117 264 4.9E-32 T 06-07-2017 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 BWK49_RS10045 1860f77b8d37c696e527d7e4976b31ce 467 Gene3D G3DSA:2.60.120.10 337 455 2.0E-16 T 06-07-2017 IPR014710 RmlC-like jelly roll fold BWK49_RS10045 1860f77b8d37c696e527d7e4976b31ce 467 PIRSF PIRSF026673 12 465 1.4E-110 T 06-07-2017 IPR016846 Predicted ion channel, cNMP-binding BWK49_RS04010 dceb18052298b7a828f006ca9578f8a3 265 Pfam PF04454 Encapsulating protein for peroxidase 1 251 2.2E-97 T 06-07-2017 IPR007544 Encapsulating protein for peroxidase GO:0008233|GO:0042742 BWK49_RS04010 dceb18052298b7a828f006ca9578f8a3 265 PIRSF PIRSF019254 1 265 7.4E-94 T 06-07-2017 IPR007544 Encapsulating protein for peroxidase GO:0008233|GO:0042742 BWK49_RS26605 115b18b2acfda349a96e49a387993b34 305 SMART SM00797 25 298 2.9E-105 T 06-07-2017 IPR003778 Carboxyltransferase domain, subdomain A and B BWK49_RS26605 115b18b2acfda349a96e49a387993b34 305 Gene3D G3DSA:2.40.100.10 175 281 1.3E-8 T 06-07-2017 IPR029000 Cyclophilin-like domain BWK49_RS26605 115b18b2acfda349a96e49a387993b34 305 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 4 288 1.9E-110 T 06-07-2017 IPR003778 Carboxyltransferase domain, subdomain A and B BWK49_RS26605 115b18b2acfda349a96e49a387993b34 305 Pfam PF02626 Allophanate hydrolase subunit 2 26 283 6.8E-78 T 06-07-2017 IPR003778 Carboxyltransferase domain, subdomain A and B BWK49_RS26605 115b18b2acfda349a96e49a387993b34 305 SUPERFAMILY SSF50891 175 283 7.96E-11 T 06-07-2017 IPR029000 Cyclophilin-like domain BWK49_RS22130 cdab62e0909a71e52dd5af7bee817d15 613 SMART SM00091 500 568 0.049 T 06-07-2017 IPR000014 PAS domain BWK49_RS22130 cdab62e0909a71e52dd5af7bee817d15 613 SMART SM00091 297 362 7.7 T 06-07-2017 IPR000014 PAS domain BWK49_RS22130 cdab62e0909a71e52dd5af7bee817d15 613 SUPERFAMILY SSF53335 72 266 4.36E-46 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS22130 cdab62e0909a71e52dd5af7bee817d15 613 Pfam PF13188 PAS domain 504 545 3.0E-4 T 06-07-2017 IPR000014 PAS domain BWK49_RS22130 cdab62e0909a71e52dd5af7bee817d15 613 Gene3D G3DSA:3.30.450.20 495 609 1.5E-11 T 06-07-2017 BWK49_RS22130 cdab62e0909a71e52dd5af7bee817d15 613 Gene3D G3DSA:3.30.450.20 302 409 1.0E-10 T 06-07-2017 BWK49_RS22130 cdab62e0909a71e52dd5af7bee817d15 613 Pfam PF01739 CheR methyltransferase, SAM binding domain 72 263 5.3E-52 T 06-07-2017 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal BWK49_RS22130 cdab62e0909a71e52dd5af7bee817d15 613 Pfam PF13426 PAS domain 312 410 1.7E-8 T 06-07-2017 IPR000014 PAS domain BWK49_RS22130 cdab62e0909a71e52dd5af7bee817d15 613 SMART SM00138 6 267 1.9E-75 T 06-07-2017 IPR000780 MCP methyltransferase, CheR-type GO:0008757 BWK49_RS22130 cdab62e0909a71e52dd5af7bee817d15 613 SUPERFAMILY SSF55785 299 409 9.07E-11 T 06-07-2017 IPR000014 PAS domain BWK49_RS22130 cdab62e0909a71e52dd5af7bee817d15 613 Pfam PF03705 CheR methyltransferase, all-alpha domain 8 58 6.4E-16 T 06-07-2017 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal BWK49_RS22130 cdab62e0909a71e52dd5af7bee817d15 613 SUPERFAMILY SSF47757 4 74 6.28E-15 T 06-07-2017 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal BWK49_RS22130 cdab62e0909a71e52dd5af7bee817d15 613 SUPERFAMILY SSF55785 490 604 2.79E-11 T 06-07-2017 IPR000014 PAS domain BWK49_RS22130 cdab62e0909a71e52dd5af7bee817d15 613 Gene3D G3DSA:3.40.50.150 71 266 1.7E-60 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS22130 cdab62e0909a71e52dd5af7bee817d15 613 PRINTS PR00996 Glutamate methyltransferase family signature 226 249 4.2E-27 T 06-07-2017 IPR000780 MCP methyltransferase, CheR-type GO:0008757 BWK49_RS22130 cdab62e0909a71e52dd5af7bee817d15 613 PRINTS PR00996 Glutamate methyltransferase family signature 65 77 4.2E-27 T 06-07-2017 IPR000780 MCP methyltransferase, CheR-type GO:0008757 BWK49_RS22130 cdab62e0909a71e52dd5af7bee817d15 613 PRINTS PR00996 Glutamate methyltransferase family signature 28 41 4.2E-27 T 06-07-2017 IPR000780 MCP methyltransferase, CheR-type GO:0008757 BWK49_RS22130 cdab62e0909a71e52dd5af7bee817d15 613 PRINTS PR00996 Glutamate methyltransferase family signature 105 125 4.2E-27 T 06-07-2017 IPR000780 MCP methyltransferase, CheR-type GO:0008757 BWK49_RS22130 cdab62e0909a71e52dd5af7bee817d15 613 PRINTS PR00996 Glutamate methyltransferase family signature 141 157 4.2E-27 T 06-07-2017 IPR000780 MCP methyltransferase, CheR-type GO:0008757 BWK49_RS22130 cdab62e0909a71e52dd5af7bee817d15 613 PRINTS PR00996 Glutamate methyltransferase family signature 207 221 4.2E-27 T 06-07-2017 IPR000780 MCP methyltransferase, CheR-type GO:0008757 BWK49_RS22130 cdab62e0909a71e52dd5af7bee817d15 613 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 504 599 7.1E-6 T 06-07-2017 IPR000014 PAS domain BWK49_RS22130 cdab62e0909a71e52dd5af7bee817d15 613 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 301 410 2.6E-7 T 06-07-2017 IPR000014 PAS domain BWK49_RS22130 cdab62e0909a71e52dd5af7bee817d15 613 Gene3D G3DSA:1.10.155.10 4 69 1.2E-16 T 06-07-2017 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal BWK49_RS09785 4cb90e774431ee5f6625c0753bd7d6d6 489 Pfam PF06974 Protein of unknown function (DUF1298) 321 460 2.6E-10 T 06-07-2017 IPR009721 O-acyltransferase WSD1, C-terminal GO:0004144 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 BWK49_RS09785 4cb90e774431ee5f6625c0753bd7d6d6 489 Pfam PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain 11 282 6.6E-79 T 06-07-2017 IPR004255 O-acyltransferase, WSD1, N-terminal GO:0004144|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 BWK49_RS09785 4cb90e774431ee5f6625c0753bd7d6d6 489 SUPERFAMILY SSF52777 40 176 2.56E-11 T 06-07-2017 BWK49_RS09785 4cb90e774431ee5f6625c0753bd7d6d6 489 TIGRFAM TIGR02946 acyl_WS_DGAT: acyltransferase, WS/DGAT/MGAT 14 464 7.5E-116 T 06-07-2017 IPR014292 Acyltransferase, WS/DGAT/MGAT GO:0016746|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 BWK49_RS22475 a385f45cf05d0ead7e396f1216480b54 270 Gene3D G3DSA:3.40.50.300 77 248 4.5E-22 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS22475 a385f45cf05d0ead7e396f1216480b54 270 Pfam PF01695 IstB-like ATP binding protein 75 248 1.4E-52 T 06-07-2017 IPR002611 IstB-like ATP-binding protein GO:0005524 BWK49_RS22475 a385f45cf05d0ead7e396f1216480b54 270 SMART SM00382 116 230 9.9E-4 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS22475 a385f45cf05d0ead7e396f1216480b54 270 PIRSF PIRSF003073 19 270 8.5E-85 T 06-07-2017 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein BWK49_RS22475 a385f45cf05d0ead7e396f1216480b54 270 SUPERFAMILY SSF52540 85 253 2.08E-25 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS10520 a385f45cf05d0ead7e396f1216480b54 270 Gene3D G3DSA:3.40.50.300 77 248 4.5E-22 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS10520 a385f45cf05d0ead7e396f1216480b54 270 Pfam PF01695 IstB-like ATP binding protein 75 248 1.4E-52 T 06-07-2017 IPR002611 IstB-like ATP-binding protein GO:0005524 BWK49_RS10520 a385f45cf05d0ead7e396f1216480b54 270 SMART SM00382 116 230 9.9E-4 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS10520 a385f45cf05d0ead7e396f1216480b54 270 PIRSF PIRSF003073 19 270 8.5E-85 T 06-07-2017 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein BWK49_RS10520 a385f45cf05d0ead7e396f1216480b54 270 SUPERFAMILY SSF52540 85 253 2.08E-25 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS07390 d24e70dd3ca2d6d3c8d1a56a4ba01539 157 Pfam PF08592 Domain of unknown function (DUF1772) 28 154 2.9E-9 T 06-07-2017 IPR013901 Protein of unknown function DUF1772 BWK49_RS23210 513f52963d34c9ac47521a38e9a9f677 144 Pfam PF01740 STAS domain 29 105 1.8E-8 T 06-07-2017 IPR002645 STAS domain BWK49_RS23210 513f52963d34c9ac47521a38e9a9f677 144 Gene3D G3DSA:3.30.750.24 19 113 9.8E-15 T 06-07-2017 IPR002645 STAS domain BWK49_RS23210 513f52963d34c9ac47521a38e9a9f677 144 SUPERFAMILY SSF52091 22 116 1.18E-13 T 06-07-2017 IPR002645 STAS domain BWK49_RS01290 461da33be17f7c528a7f7972366970bf 398 Gene3D G3DSA:3.40.640.10 49 262 1.5E-36 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 BWK49_RS01290 461da33be17f7c528a7f7972366970bf 398 SUPERFAMILY SSF53383 3 396 4.93E-57 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase BWK49_RS01290 461da33be17f7c528a7f7972366970bf 398 Pfam PF00266 Aminotransferase class-V 21 390 2.6E-33 T 06-07-2017 IPR000192 Aminotransferase class V domain BWK49_RS01290 461da33be17f7c528a7f7972366970bf 398 TIGRFAM TIGR01976 am_tr_V_VC1184: cysteine desulfurase family protein 3 394 3.9E-143 T 06-07-2017 IPR011340 Cysteine desulfurase-related BWK49_RS01290 461da33be17f7c528a7f7972366970bf 398 Gene3D G3DSA:3.90.1150.10 263 397 2.6E-20 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 BWK49_RS10770 8f847eb39f7de3e4860e3060a9e159fd 387 SUPERFAMILY SSF51735 175 353 2.3E-30 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS10770 8f847eb39f7de3e4860e3060a9e159fd 387 SUPERFAMILY SSF50129 1 207 3.96E-54 T 06-07-2017 IPR011032 GroES-like BWK49_RS10770 8f847eb39f7de3e4860e3060a9e159fd 387 SUPERFAMILY SSF50129 337 386 3.65E-9 T 06-07-2017 IPR011032 GroES-like BWK49_RS10770 8f847eb39f7de3e4860e3060a9e159fd 387 Gene3D G3DSA:3.90.180.10 2 209 5.6E-57 T 06-07-2017 IPR011032 GroES-like BWK49_RS10770 8f847eb39f7de3e4860e3060a9e159fd 387 Gene3D G3DSA:3.40.50.720 210 331 3.5E-23 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS10770 8f847eb39f7de3e4860e3060a9e159fd 387 SMART SM00829 10 384 4.7E-4 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 BWK49_RS10770 8f847eb39f7de3e4860e3060a9e159fd 387 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 171 4.0E-27 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 BWK49_RS10770 8f847eb39f7de3e4860e3060a9e159fd 387 Pfam PF00107 Zinc-binding dehydrogenase 213 343 5.6E-18 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 BWK49_RS10770 8f847eb39f7de3e4860e3060a9e159fd 387 TIGRFAM TIGR03989 Rxyl_3153: NDMA-dependent alcohol dehydrogenase, Rxyl_3153 family 2 386 4.4E-147 T 06-07-2017 IPR023921 Alcohol dehydrogenase, zinc-type, actinomycetes KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396 BWK49_RS10770 8f847eb39f7de3e4860e3060a9e159fd 387 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 77 91 - T 06-07-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 BWK49_RS11865 87b645292c06a3a304688a12fea3f31d 782 SUPERFAMILY SSF89796 375 775 5.89E-97 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS11865 87b645292c06a3a304688a12fea3f31d 782 SUPERFAMILY SSF89796 2 355 2.49E-77 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS11865 87b645292c06a3a304688a12fea3f31d 782 Pfam PF02515 CoA-transferase family III 4 355 1.4E-71 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 BWK49_RS11865 87b645292c06a3a304688a12fea3f31d 782 Pfam PF02515 CoA-transferase family III 377 750 1.2E-98 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 BWK49_RS11865 87b645292c06a3a304688a12fea3f31d 782 Gene3D G3DSA:3.40.50.10540 293 355 1.7E-64 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS11865 87b645292c06a3a304688a12fea3f31d 782 Gene3D G3DSA:3.40.50.10540 374 592 2.1E-80 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS11865 87b645292c06a3a304688a12fea3f31d 782 Gene3D G3DSA:3.40.50.10540 2 204 1.7E-64 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS11865 87b645292c06a3a304688a12fea3f31d 782 Gene3D G3DSA:3.40.50.10540 682 774 2.1E-80 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS11865 87b645292c06a3a304688a12fea3f31d 782 Gene3D G3DSA:3.30.1540.10 599 681 4.0E-22 T 06-07-2017 BWK49_RS11865 87b645292c06a3a304688a12fea3f31d 782 Gene3D G3DSA:3.30.1540.10 226 292 5.0E-17 T 06-07-2017 BWK49_RS16740 be29c8875789c46638463c1d4d57801c 565 SUPERFAMILY SSF51905 43 332 6.34E-58 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS16740 be29c8875789c46638463c1d4d57801c 565 SUPERFAMILY SSF51905 490 548 6.34E-58 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS16740 be29c8875789c46638463c1d4d57801c 565 Pfam PF05199 GMC oxidoreductase 426 541 2.2E-27 T 06-07-2017 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 BWK49_RS16740 be29c8875789c46638463c1d4d57801c 565 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 47 69 8.4E-5 T 06-07-2017 BWK49_RS16740 be29c8875789c46638463c1d4d57801c 565 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 466 481 8.4E-5 T 06-07-2017 BWK49_RS16740 be29c8875789c46638463c1d4d57801c 565 Pfam PF00732 GMC oxidoreductase 47 315 1.1E-13 T 06-07-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 BWK49_RS16740 be29c8875789c46638463c1d4d57801c 565 SUPERFAMILY SSF54373 372 474 7.65E-9 T 06-07-2017 BWK49_RS16740 be29c8875789c46638463c1d4d57801c 565 Gene3D G3DSA:3.50.50.60 234 340 1.7E-75 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS16740 be29c8875789c46638463c1d4d57801c 565 Gene3D G3DSA:3.50.50.60 435 448 1.7E-75 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS16740 be29c8875789c46638463c1d4d57801c 565 Gene3D G3DSA:3.50.50.60 481 547 1.7E-75 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS16740 be29c8875789c46638463c1d4d57801c 565 Gene3D G3DSA:3.50.50.60 43 168 1.7E-75 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS08575 3ee74f1b02180bfcf2f8ad78d914e4f6 470 Gene3D G3DSA:3.40.190.10 76 168 2.5E-12 T 06-07-2017 BWK49_RS08575 3ee74f1b02180bfcf2f8ad78d914e4f6 470 SUPERFAMILY SSF53850 39 291 3.22E-59 T 06-07-2017 BWK49_RS08575 3ee74f1b02180bfcf2f8ad78d914e4f6 470 SUPERFAMILY SSF53850 333 441 3.22E-59 T 06-07-2017 BWK49_RS08575 3ee74f1b02180bfcf2f8ad78d914e4f6 470 Pfam PF01547 Bacterial extracellular solute-binding protein 46 376 6.4E-30 T 06-07-2017 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 BWK49_RS08575 3ee74f1b02180bfcf2f8ad78d914e4f6 470 Gene3D G3DSA:3.40.190.10 333 394 4.6E-47 T 06-07-2017 BWK49_RS08575 3ee74f1b02180bfcf2f8ad78d914e4f6 470 Gene3D G3DSA:3.40.190.10 169 291 4.6E-47 T 06-07-2017 BWK49_RS11520 c7abc566bd3b4e26dcbf471c0bb28d17 425 Pfam PF01966 HD domain 72 221 1.2E-19 T 06-07-2017 IPR006674 HD domain BWK49_RS11520 c7abc566bd3b4e26dcbf471c0bb28d17 425 Pfam PF13286 Phosphohydrolase-associated domain 330 419 1.7E-15 T 06-07-2017 IPR026875 Phosphohydrolase-associated domain BWK49_RS11520 c7abc566bd3b4e26dcbf471c0bb28d17 425 SMART SM00471 68 231 8.6E-13 T 06-07-2017 IPR003607 HD/PDEase domain BWK49_RS11520 c7abc566bd3b4e26dcbf471c0bb28d17 425 Hamap MF_01212 Deoxyguanosinetriphosphate triphosphohydrolase-like protein. 3 423 31.441 T 06-07-2017 IPR023023 Deoxyguanosinetriphosphate triphosphohydrolase, type 2 BWK49_RS11520 c7abc566bd3b4e26dcbf471c0bb28d17 425 Gene3D G3DSA:1.10.3410.10 218 348 1.7E-15 T 06-07-2017 IPR023293 Deoxyguanosinetriphosphate triphosphohydrolase, central domain BWK49_RS11520 c7abc566bd3b4e26dcbf471c0bb28d17 425 Gene3D G3DSA:1.10.3210.10 28 217 1.4E-63 T 06-07-2017 IPR006674 HD domain BWK49_RS11520 c7abc566bd3b4e26dcbf471c0bb28d17 425 SUPERFAMILY SSF109604 202 242 3.53E-55 T 06-07-2017 BWK49_RS11520 c7abc566bd3b4e26dcbf471c0bb28d17 425 SUPERFAMILY SSF109604 34 172 3.53E-55 T 06-07-2017 BWK49_RS11520 c7abc566bd3b4e26dcbf471c0bb28d17 425 TIGRFAM TIGR01353 dGTP_triPase: putative dGTPase 34 411 1.8E-71 T 06-07-2017 IPR006261 Deoxyguanosinetriphosphate triphosphohydrolase GO:0000287|GO:0008832|GO:0046039 BWK49_RS10855 36e0a0b4ad42abfe9050985d34bb5e90 410 SUPERFAMILY SSF89796 10 409 1.96E-103 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS10855 36e0a0b4ad42abfe9050985d34bb5e90 410 Gene3D G3DSA:3.30.1540.10 246 319 9.5E-19 T 06-07-2017 BWK49_RS10855 36e0a0b4ad42abfe9050985d34bb5e90 410 Pfam PF02515 CoA-transferase family III 11 386 4.5E-90 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 BWK49_RS10855 36e0a0b4ad42abfe9050985d34bb5e90 410 Gene3D G3DSA:3.40.50.10540 8 228 2.4E-84 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS10855 36e0a0b4ad42abfe9050985d34bb5e90 410 Gene3D G3DSA:3.40.50.10540 320 409 2.4E-84 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS14800 73f67b1882256159ca8c3eff8cfe9881 159 TIGRFAM TIGR00754 bfr: bacterioferritin 1 156 3.9E-75 T 06-07-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 BWK49_RS14800 73f67b1882256159ca8c3eff8cfe9881 159 PRINTS PR00601 Bacterioferritin signature 107 127 2.9E-66 T 06-07-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 BWK49_RS14800 73f67b1882256159ca8c3eff8cfe9881 159 PRINTS PR00601 Bacterioferritin signature 3 22 2.9E-66 T 06-07-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 BWK49_RS14800 73f67b1882256159ca8c3eff8cfe9881 159 PRINTS PR00601 Bacterioferritin signature 128 149 2.9E-66 T 06-07-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 BWK49_RS14800 73f67b1882256159ca8c3eff8cfe9881 159 PRINTS PR00601 Bacterioferritin signature 44 64 2.9E-66 T 06-07-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 BWK49_RS14800 73f67b1882256159ca8c3eff8cfe9881 159 PRINTS PR00601 Bacterioferritin signature 65 85 2.9E-66 T 06-07-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 BWK49_RS14800 73f67b1882256159ca8c3eff8cfe9881 159 PRINTS PR00601 Bacterioferritin signature 23 43 2.9E-66 T 06-07-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 BWK49_RS14800 73f67b1882256159ca8c3eff8cfe9881 159 PRINTS PR00601 Bacterioferritin signature 86 106 2.9E-66 T 06-07-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 BWK49_RS14800 73f67b1882256159ca8c3eff8cfe9881 159 PIRSF PIRSF002560 1 157 7.4E-65 T 06-07-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 BWK49_RS14800 73f67b1882256159ca8c3eff8cfe9881 159 ProSitePatterns PS00549 Bacterioferritin signature. 1 19 - T 06-07-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 BWK49_RS14800 73f67b1882256159ca8c3eff8cfe9881 159 Pfam PF00210 Ferritin-like domain 10 143 4.9E-35 T 06-07-2017 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 BWK49_RS14800 73f67b1882256159ca8c3eff8cfe9881 159 SUPERFAMILY SSF47240 1 152 9.76E-47 T 06-07-2017 IPR009078 Ferritin-like superfamily BWK49_RS14800 73f67b1882256159ca8c3eff8cfe9881 159 Gene3D G3DSA:1.20.1260.10 1 154 9.6E-56 T 06-07-2017 IPR012347 Ferritin-related BWK49_RS17660 bd58c367cc4100815f73e0ccce3d6559 364 TIGRFAM TIGR02622 CDP_4_6_dhtase: CDP-glucose 4,6-dehydratase 13 340 8.4E-142 T 06-07-2017 IPR013445 CDP-glucose 4,6-dehydratase KEGG: 00520+4.2.1.45|MetaCyc: PWY-5833 BWK49_RS17660 bd58c367cc4100815f73e0ccce3d6559 364 Gene3D G3DSA:3.90.25.10 197 342 9.3E-41 T 06-07-2017 BWK49_RS17660 bd58c367cc4100815f73e0ccce3d6559 364 Gene3D G3DSA:3.40.50.720 12 196 1.1E-41 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS17660 bd58c367cc4100815f73e0ccce3d6559 364 Pfam PF16363 GDP-mannose 4,6 dehydratase 19 326 2.3E-36 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS17660 bd58c367cc4100815f73e0ccce3d6559 364 SUPERFAMILY SSF51735 15 335 4.53E-64 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS04190 4302051acc13522faea6bde36aba040f 115 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 5 20 1.6E-13 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 BWK49_RS04190 4302051acc13522faea6bde36aba040f 115 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 24 35 1.6E-13 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 BWK49_RS04190 4302051acc13522faea6bde36aba040f 115 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 37 52 1.6E-13 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 BWK49_RS04190 4302051acc13522faea6bde36aba040f 115 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 52 67 1.6E-13 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 BWK49_RS04190 4302051acc13522faea6bde36aba040f 115 SMART SM00418 3 81 7.3E-30 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 BWK49_RS04190 4302051acc13522faea6bde36aba040f 115 Pfam PF01022 Bacterial regulatory protein, arsR family 10 55 4.3E-13 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 BWK49_RS04190 4302051acc13522faea6bde36aba040f 115 Gene3D G3DSA:1.10.10.10 2 76 1.0E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS04190 4302051acc13522faea6bde36aba040f 115 SUPERFAMILY SSF46785 2 75 6.45E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS18535 e1d0a4c8c4eae0128965232be054d441 252 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 38 52 4.1E-10 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 BWK49_RS18535 e1d0a4c8c4eae0128965232be054d441 252 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 52 68 4.1E-10 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 BWK49_RS18535 e1d0a4c8c4eae0128965232be054d441 252 Pfam PF07702 UTRA domain 103 237 8.1E-29 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 BWK49_RS18535 e1d0a4c8c4eae0128965232be054d441 252 SMART SM00345 21 78 6.3E-13 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 BWK49_RS18535 e1d0a4c8c4eae0128965232be054d441 252 Gene3D G3DSA:1.10.10.10 13 75 6.0E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS18535 e1d0a4c8c4eae0128965232be054d441 252 Gene3D G3DSA:3.40.1410.10 76 241 3.5E-34 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain BWK49_RS18535 e1d0a4c8c4eae0128965232be054d441 252 SUPERFAMILY SSF46785 13 82 3.88E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS18535 e1d0a4c8c4eae0128965232be054d441 252 SUPERFAMILY SSF64288 66 240 9.11E-36 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain BWK49_RS18535 e1d0a4c8c4eae0128965232be054d441 252 Pfam PF00392 Bacterial regulatory proteins, gntR family 18 78 2.1E-14 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 BWK49_RS18535 e1d0a4c8c4eae0128965232be054d441 252 SMART SM00866 99 238 4.6E-26 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 BWK49_RS16445 285effb4e7655b1ec5aee2045a2083e9 751 Pfam PF00403 Heavy-metal-associated domain 16 72 1.0E-12 T 06-07-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 BWK49_RS16445 285effb4e7655b1ec5aee2045a2083e9 751 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 613 629 5.4E-7 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 BWK49_RS16445 285effb4e7655b1ec5aee2045a2083e9 751 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 672 697 5.4E-7 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 BWK49_RS16445 285effb4e7655b1ec5aee2045a2083e9 751 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 641 657 5.4E-7 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 BWK49_RS16445 285effb4e7655b1ec5aee2045a2083e9 751 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 443 449 - T 06-07-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 BWK49_RS16445 285effb4e7655b1ec5aee2045a2083e9 751 Gene3D G3DSA:3.40.50.1000 412 457 1.9E-53 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS16445 285effb4e7655b1ec5aee2045a2083e9 751 Gene3D G3DSA:3.40.50.1000 569 709 1.9E-53 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS16445 285effb4e7655b1ec5aee2045a2083e9 751 SUPERFAMILY SSF81653 248 341 6.8E-23 T 06-07-2017 BWK49_RS16445 285effb4e7655b1ec5aee2045a2083e9 751 Pfam PF00702 haloacid dehalogenase-like hydrolase 437 655 5.2E-47 T 06-07-2017 BWK49_RS16445 285effb4e7655b1ec5aee2045a2083e9 751 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 215 721 4.3E-89 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 BWK49_RS16445 285effb4e7655b1ec5aee2045a2083e9 751 Gene3D G3DSA:3.30.70.100 13 76 2.6E-23 T 06-07-2017 BWK49_RS16445 285effb4e7655b1ec5aee2045a2083e9 751 ProSitePatterns PS01047 Heavy-metal-associated domain. 17 45 - T 06-07-2017 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 BWK49_RS16445 285effb4e7655b1ec5aee2045a2083e9 751 SUPERFAMILY SSF56784 439 459 1.53E-56 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS16445 285effb4e7655b1ec5aee2045a2083e9 751 SUPERFAMILY SSF56784 498 741 1.53E-56 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS16445 285effb4e7655b1ec5aee2045a2083e9 751 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 206 744 5.6E-155 T 06-07-2017 BWK49_RS16445 285effb4e7655b1ec5aee2045a2083e9 751 SUPERFAMILY SSF81665 342 435 3.92E-12 T 06-07-2017 BWK49_RS16445 285effb4e7655b1ec5aee2045a2083e9 751 SUPERFAMILY SSF81665 214 245 3.92E-12 T 06-07-2017 BWK49_RS16445 285effb4e7655b1ec5aee2045a2083e9 751 SUPERFAMILY SSF81665 690 715 3.92E-12 T 06-07-2017 BWK49_RS16445 285effb4e7655b1ec5aee2045a2083e9 751 Pfam PF00122 E1-E2 ATPase 214 432 9.4E-64 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 BWK49_RS16445 285effb4e7655b1ec5aee2045a2083e9 751 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 664 676 5.8E-25 T 06-07-2017 BWK49_RS16445 285effb4e7655b1ec5aee2045a2083e9 751 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 566 577 5.8E-25 T 06-07-2017 BWK49_RS16445 285effb4e7655b1ec5aee2045a2083e9 751 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 641 660 5.8E-25 T 06-07-2017 BWK49_RS16445 285effb4e7655b1ec5aee2045a2083e9 751 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 441 455 5.8E-25 T 06-07-2017 BWK49_RS16445 285effb4e7655b1ec5aee2045a2083e9 751 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 291 305 5.8E-25 T 06-07-2017 BWK49_RS16445 285effb4e7655b1ec5aee2045a2083e9 751 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 588 598 5.8E-25 T 06-07-2017 BWK49_RS16445 285effb4e7655b1ec5aee2045a2083e9 751 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 160 743 5.8E-178 T 06-07-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 BWK49_RS16445 285effb4e7655b1ec5aee2045a2083e9 751 Gene3D G3DSA:2.70.150.10 203 342 2.1E-25 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 BWK49_RS16445 285effb4e7655b1ec5aee2045a2083e9 751 Gene3D G3DSA:3.40.1110.10 458 568 2.5E-24 T 06-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 BWK49_RS16445 285effb4e7655b1ec5aee2045a2083e9 751 SUPERFAMILY SSF55008 12 79 1.96E-19 T 06-07-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 BWK49_RS13190 df7b9f83fae990dfee0278a4e2d90aa5 262 TIGRFAM TIGR03843 TIGR03843: conserved hypothetical protein 2 262 1.3E-111 T 06-07-2017 IPR022292 Conserved hypothetical protein CHP03843 BWK49_RS11105 4da7d86d5a957489ce1f9615e4b3f9db 359 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 73 331 2.0E-16 T 06-07-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 BWK49_RS11105 4da7d86d5a957489ce1f9615e4b3f9db 359 Gene3D G3DSA:3.40.50.720 71 129 1.4E-21 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS11105 4da7d86d5a957489ce1f9615e4b3f9db 359 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 161 188 - T 06-07-2017 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 BWK49_RS11105 4da7d86d5a957489ce1f9615e4b3f9db 359 SUPERFAMILY SSF51735 117 299 6.95E-55 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS11105 4da7d86d5a957489ce1f9615e4b3f9db 359 Gene3D G3DSA:3.40.50.720 130 300 1.6E-61 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS11105 4da7d86d5a957489ce1f9615e4b3f9db 359 SUPERFAMILY SSF52283 56 143 1.21E-18 T 06-07-2017 BWK49_RS11105 4da7d86d5a957489ce1f9615e4b3f9db 359 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 124 299 1.1E-57 T 06-07-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 BWK49_RS01160 a7f826fe071320e1fb9f9d3e31999518 300 Pfam PF00756 Putative esterase 45 294 4.2E-51 T 06-07-2017 IPR000801 Putative esterase Reactome: R-HSA-156590 BWK49_RS01160 a7f826fe071320e1fb9f9d3e31999518 300 Gene3D G3DSA:3.40.50.1820 39 298 4.6E-71 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS01160 a7f826fe071320e1fb9f9d3e31999518 300 SUPERFAMILY SSF53474 39 295 1.03E-25 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS16390 22d1a2dd012c6017551427296e2921d3 444 TIGRFAM TIGR00797 matE: MATE efflux family protein 24 415 6.7E-93 T 06-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 BWK49_RS16390 22d1a2dd012c6017551427296e2921d3 444 Pfam PF01554 MatE 24 183 3.6E-25 T 06-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 BWK49_RS16390 22d1a2dd012c6017551427296e2921d3 444 Pfam PF01554 MatE 244 396 1.5E-18 T 06-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 BWK49_RS16200 f3deb1ddd7f9af4edbfa748ccebaa596 94 Pfam PF06013 Proteins of 100 residues with WXG 3 87 6.4E-14 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like BWK49_RS16200 f3deb1ddd7f9af4edbfa748ccebaa596 94 Gene3D G3DSA:1.10.287.1060 2 94 3.1E-14 T 06-07-2017 BWK49_RS16200 f3deb1ddd7f9af4edbfa748ccebaa596 94 SUPERFAMILY SSF140453 2 93 2.35E-17 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like BWK49_RS13290 a73ff438f67e47fd9e0bcfb6504bc64f 255 Pfam PF11738 Protein of unknown function (DUF3298) 148 247 6.4E-9 T 06-07-2017 IPR021729 Domain of unknown function DUF3298 BWK49_RS13290 a73ff438f67e47fd9e0bcfb6504bc64f 255 Pfam PF12151 Mannan-binding protein 22 57 9.4E-17 T 06-07-2017 IPR021992 Mannan-binding protein BWK49_RS21060 07987641addd4bb129d753cd0677874b 358 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 2 353 5.1E-85 T 06-07-2017 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 BWK49_RS21060 07987641addd4bb129d753cd0677874b 358 SUPERFAMILY SSF52402 2 238 3.53E-48 T 06-07-2017 BWK49_RS21060 07987641addd4bb129d753cd0677874b 358 Gene3D G3DSA:3.40.50.620 2 204 5.3E-75 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold BWK49_RS21060 07987641addd4bb129d753cd0677874b 358 Gene3D G3DSA:2.40.30.10 273 356 4.4E-17 T 06-07-2017 BWK49_RS21060 07987641addd4bb129d753cd0677874b 358 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 1 354 36.154 T 06-07-2017 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 BWK49_RS21060 07987641addd4bb129d753cd0677874b 358 Gene3D G3DSA:2.30.30.280 210 270 5.1E-15 T 06-07-2017 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 Reactome: R-HSA-6787450 BWK49_RS21060 07987641addd4bb129d753cd0677874b 358 Pfam PF03054 tRNA methyl transferase 2 353 6.7E-115 T 06-07-2017 BWK49_RS28820 30b99a918c9200ded5f93c5dca272e2b 231 Gene3D G3DSA:3.40.50.300 1 228 3.0E-14 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS28820 30b99a918c9200ded5f93c5dca272e2b 231 SUPERFAMILY SSF52540 1 191 1.36E-12 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS09680 4ef06b2f23057ecb27e9ac6ecb9ba0a5 403 SUPERFAMILY SSF141523 251 372 3.79E-27 T 06-07-2017 BWK49_RS09680 4ef06b2f23057ecb27e9ac6ecb9ba0a5 403 Gene3D G3DSA:2.40.440.10 253 373 1.3E-17 T 06-07-2017 BWK49_RS09680 4ef06b2f23057ecb27e9ac6ecb9ba0a5 403 Pfam PF03734 L,D-transpeptidase catalytic domain 253 372 2.5E-15 T 06-07-2017 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 BWK49_RS07925 aa19faeeb0c64828a57bf9890a9c80fa 122 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 119 10.694 T 06-07-2017 IPR022907 VapC family GO:0004540 BWK49_RS07925 aa19faeeb0c64828a57bf9890a9c80fa 122 Pfam PF01850 PIN domain 2 111 4.2E-6 T 06-07-2017 IPR002716 PIN domain BWK49_RS07925 aa19faeeb0c64828a57bf9890a9c80fa 122 SUPERFAMILY SSF88723 1 111 1.85E-12 T 06-07-2017 IPR029060 PIN domain-like BWK49_RS24890 16e2b7853a2bf75ec75e07aa01d48c59 148 SUPERFAMILY SSF54593 2 145 6.74E-14 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS24890 16e2b7853a2bf75ec75e07aa01d48c59 148 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 3 143 2.9E-6 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain BWK49_RS24890 16e2b7853a2bf75ec75e07aa01d48c59 148 Gene3D G3DSA:3.10.180.10 3 145 7.6E-14 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS12525 a614c4fed596fa746f7db947193f6d85 165 Gene3D G3DSA:3.40.50.270 5 158 2.9E-47 T 06-07-2017 BWK49_RS12525 a614c4fed596fa746f7db947193f6d85 165 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 9 150 6.4E-44 T 06-07-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily BWK49_RS12525 a614c4fed596fa746f7db947193f6d85 165 SMART SM00226 7 154 3.5E-59 T 06-07-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily BWK49_RS12525 a614c4fed596fa746f7db947193f6d85 165 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 84 99 8.7E-21 T 06-07-2017 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 BWK49_RS12525 a614c4fed596fa746f7db947193f6d85 165 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 52 68 8.7E-21 T 06-07-2017 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 BWK49_RS12525 a614c4fed596fa746f7db947193f6d85 165 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 126 141 8.7E-21 T 06-07-2017 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 BWK49_RS12525 a614c4fed596fa746f7db947193f6d85 165 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 9 26 8.7E-21 T 06-07-2017 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 BWK49_RS12525 a614c4fed596fa746f7db947193f6d85 165 SUPERFAMILY SSF52788 6 155 1.1E-43 T 06-07-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily BWK49_RS04780 b50d51be0a8c89d64a3c16548c8a3d0f 432 SUPERFAMILY SSF48264 33 430 5.24E-84 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS04780 b50d51be0a8c89d64a3c16548c8a3d0f 432 Pfam PF00067 Cytochrome P450 230 400 2.2E-15 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS04780 b50d51be0a8c89d64a3c16548c8a3d0f 432 PRINTS PR00359 B-class P450 signature 160 176 8.1E-39 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS04780 b50d51be0a8c89d64a3c16548c8a3d0f 432 PRINTS PR00359 B-class P450 signature 222 244 8.1E-39 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS04780 b50d51be0a8c89d64a3c16548c8a3d0f 432 PRINTS PR00359 B-class P450 signature 304 315 8.1E-39 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS04780 b50d51be0a8c89d64a3c16548c8a3d0f 432 PRINTS PR00359 B-class P450 signature 114 125 8.1E-39 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS04780 b50d51be0a8c89d64a3c16548c8a3d0f 432 PRINTS PR00359 B-class P450 signature 380 391 8.1E-39 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS04780 b50d51be0a8c89d64a3c16548c8a3d0f 432 PRINTS PR00359 B-class P450 signature 349 364 8.1E-39 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS04780 b50d51be0a8c89d64a3c16548c8a3d0f 432 PRINTS PR00359 B-class P450 signature 371 380 8.1E-39 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS04780 b50d51be0a8c89d64a3c16548c8a3d0f 432 PRINTS PR00359 B-class P450 signature 321 348 8.1E-39 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS04780 b50d51be0a8c89d64a3c16548c8a3d0f 432 PRINTS PR00359 B-class P450 signature 177 192 8.1E-39 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS04780 b50d51be0a8c89d64a3c16548c8a3d0f 432 Gene3D G3DSA:1.10.630.10 32 430 1.2E-106 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS05530 0f62e4e5d755631e7c855a96865f6217 108 Pfam PF00037 4Fe-4S binding domain 34 56 1.2E-8 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain BWK49_RS05530 0f62e4e5d755631e7c855a96865f6217 108 PRINTS PR00354 7Fe ferredoxin signature 9 19 4.7E-18 T 06-07-2017 IPR000813 7Fe ferredoxin GO:0009055 BWK49_RS05530 0f62e4e5d755631e7c855a96865f6217 108 PRINTS PR00354 7Fe ferredoxin signature 19 29 4.7E-18 T 06-07-2017 IPR000813 7Fe ferredoxin GO:0009055 BWK49_RS05530 0f62e4e5d755631e7c855a96865f6217 108 PRINTS PR00354 7Fe ferredoxin signature 35 52 4.7E-18 T 06-07-2017 IPR000813 7Fe ferredoxin GO:0009055 BWK49_RS05530 0f62e4e5d755631e7c855a96865f6217 108 Gene3D G3DSA:3.30.70.20 4 80 6.7E-19 T 06-07-2017 BWK49_RS05530 0f62e4e5d755631e7c855a96865f6217 108 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site BWK49_RS05530 0f62e4e5d755631e7c855a96865f6217 108 SUPERFAMILY SSF54862 4 84 5.07E-20 T 06-07-2017 BWK49_RS07540 47f33d013a0d9f659a053a9fcd8a3f30 226 SUPERFAMILY SSF52172 1 185 1.99E-43 T 06-07-2017 IPR011006 CheY-like superfamily BWK49_RS07540 47f33d013a0d9f659a053a9fcd8a3f30 226 SMART SM00448 2 112 1.1E-43 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 BWK49_RS07540 47f33d013a0d9f659a053a9fcd8a3f30 226 Gene3D G3DSA:3.40.50.2300 1 124 1.3E-37 T 06-07-2017 BWK49_RS07540 47f33d013a0d9f659a053a9fcd8a3f30 226 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 224 6.8E-23 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 BWK49_RS07540 47f33d013a0d9f659a053a9fcd8a3f30 226 SMART SM00862 148 224 1.2E-23 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 BWK49_RS07540 47f33d013a0d9f659a053a9fcd8a3f30 226 Gene3D G3DSA:1.10.10.10 126 225 6.1E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS07540 47f33d013a0d9f659a053a9fcd8a3f30 226 Pfam PF00072 Response regulator receiver domain 4 112 1.5E-27 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 BWK49_RS18810 6c271e6e9f512ad71e11fcd9fdc69b97 446 Pfam PF00202 Aminotransferase class-III 37 440 1.1E-131 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 BWK49_RS18810 6c271e6e9f512ad71e11fcd9fdc69b97 446 Gene3D G3DSA:3.90.1150.10 328 445 3.7E-39 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 BWK49_RS18810 6c271e6e9f512ad71e11fcd9fdc69b97 446 Gene3D G3DSA:3.40.640.10 75 327 1.7E-80 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 BWK49_RS18810 6c271e6e9f512ad71e11fcd9fdc69b97 446 SUPERFAMILY SSF53383 38 445 2.42E-124 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase BWK49_RS18810 6c271e6e9f512ad71e11fcd9fdc69b97 446 TIGRFAM TIGR00700 GABAtrnsam: 4-aminobutyrate transaminase 24 445 1.0E-212 T 06-07-2017 IPR004632 4-aminobutyrate aminotransferase, bacterial GO:0003867|GO:0009448 BWK49_RS18810 6c271e6e9f512ad71e11fcd9fdc69b97 446 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 259 296 - T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 BWK49_RS04500 2766b10ec60cec63b1238f23d7120827 598 Pfam PF00271 Helicase conserved C-terminal domain 288 384 5.1E-5 T 06-07-2017 IPR001650 Helicase, C-terminal BWK49_RS04500 2766b10ec60cec63b1238f23d7120827 598 SUPERFAMILY SSF52540 254 386 8.29E-21 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS04500 2766b10ec60cec63b1238f23d7120827 598 SUPERFAMILY SSF52540 39 87 8.29E-21 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS04500 2766b10ec60cec63b1238f23d7120827 598 SUPERFAMILY SSF52540 125 189 8.29E-21 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS04500 2766b10ec60cec63b1238f23d7120827 598 Gene3D G3DSA:3.40.50.300 271 384 1.3E-11 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS04500 2766b10ec60cec63b1238f23d7120827 598 Gene3D G3DSA:3.40.50.300 14 193 4.0E-15 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS04500 2766b10ec60cec63b1238f23d7120827 598 Pfam PF04851 Type III restriction enzyme, res subunit 18 187 2.0E-17 T 06-07-2017 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 BWK49_RS04500 2766b10ec60cec63b1238f23d7120827 598 SMART SM00487 15 214 6.0E-5 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain BWK49_RS05655 f8890497edaef9447566edecfdd1d6ba 131 ProDom PD030784 PRECURSOR SIGNAL TRANSCRIPTIONAL PROBABLE RV1990C/MT2044 REGULATORY MB3210 MB2012C 40 107 3.0E-9 T 06-07-2017 BWK49_RS26535 b79a437d1f5fe1c1e8770cb42d7f78df 193 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 15 163 9.5E-23 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain BWK49_RS26535 b79a437d1f5fe1c1e8770cb42d7f78df 193 Gene3D G3DSA:3.10.180.10 2 175 2.4E-44 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS26535 b79a437d1f5fe1c1e8770cb42d7f78df 193 SUPERFAMILY SSF54593 12 165 1.32E-27 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS26535 b79a437d1f5fe1c1e8770cb42d7f78df 193 ProSitePatterns PS00082 Extradiol ring-cleavage dioxygenases signature. 141 162 - T 06-07-2017 IPR000486 Extradiol ring-cleavage dioxygenase, class I /II GO:0003824|GO:0006725|GO:0008198|GO:0055114 BWK49_RS08610 a010066190a9e90ca5cae2077a9fd91e 329 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 157 324 4.0E-34 T 06-07-2017 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 BWK49_RS08610 a010066190a9e90ca5cae2077a9fd91e 329 Gene3D G3DSA:3.90.110.10 156 326 8.0E-76 T 06-07-2017 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 BWK49_RS08610 a010066190a9e90ca5cae2077a9fd91e 329 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 7 151 2.2E-31 T 06-07-2017 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 BWK49_RS08610 a010066190a9e90ca5cae2077a9fd91e 329 TIGRFAM TIGR01759 MalateDH-SF1: malate dehydrogenase 4 322 3.7E-146 T 06-07-2017 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 BWK49_RS08610 a010066190a9e90ca5cae2077a9fd91e 329 SUPERFAMILY SSF51735 4 155 3.31E-42 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS08610 a010066190a9e90ca5cae2077a9fd91e 329 Hamap MF_01517 Malate dehydrogenase [mdh]. 2 327 56.54 T 06-07-2017 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 BWK49_RS08610 a010066190a9e90ca5cae2077a9fd91e 329 Gene3D G3DSA:3.40.50.720 4 154 1.8E-52 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS08610 a010066190a9e90ca5cae2077a9fd91e 329 SUPERFAMILY SSF56327 157 325 5.87E-61 T 06-07-2017 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 BWK49_RS08610 a010066190a9e90ca5cae2077a9fd91e 329 PIRSF PIRSF000102 2 327 3.4E-57 T 06-07-2017 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 BWK49_RS08610 a010066190a9e90ca5cae2077a9fd91e 329 ProSitePatterns PS00068 Malate dehydrogenase active site signature. 156 168 - T 06-07-2017 IPR001252 Malate dehydrogenase, active site GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383|Reactome: R-HSA-70263 BWK49_RS10105 0786be402cc51449edd2c7fae18c0812 588 Gene3D G3DSA:3.30.300.30 465 576 3.8E-14 T 06-07-2017 BWK49_RS10105 0786be402cc51449edd2c7fae18c0812 588 Pfam PF00501 AMP-binding enzyme 17 474 1.3E-65 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS10105 0786be402cc51449edd2c7fae18c0812 588 Gene3D G3DSA:3.40.50.980 5 175 5.4E-24 T 06-07-2017 BWK49_RS10105 0786be402cc51449edd2c7fae18c0812 588 SUPERFAMILY SSF56801 5 347 6.28E-89 T 06-07-2017 BWK49_RS10105 0786be402cc51449edd2c7fae18c0812 588 SUPERFAMILY SSF56801 377 581 6.28E-89 T 06-07-2017 BWK49_RS10105 0786be402cc51449edd2c7fae18c0812 588 Gene3D G3DSA:3.40.50.980 176 350 7.7E-27 T 06-07-2017 BWK49_RS10105 0786be402cc51449edd2c7fae18c0812 588 Gene3D G3DSA:2.30.38.10 390 464 1.5E-16 T 06-07-2017 BWK49_RS09040 28691bbac8ad5561325db8f8891b7c7c 495 SMART SM00342 100 183 1.6E-19 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 BWK49_RS09040 28691bbac8ad5561325db8f8891b7c7c 495 Gene3D G3DSA:1.10.340.30 319 433 4.7E-34 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 BWK49_RS09040 28691bbac8ad5561325db8f8891b7c7c 495 SUPERFAMILY SSF48150 306 480 7.15E-42 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 BWK49_RS09040 28691bbac8ad5561325db8f8891b7c7c 495 SMART SM00478 326 483 5.4E-31 T 06-07-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 BWK49_RS09040 28691bbac8ad5561325db8f8891b7c7c 495 Gene3D G3DSA:1.10.10.60 83 137 4.2E-4 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS09040 28691bbac8ad5561325db8f8891b7c7c 495 Pfam PF06029 AlkA N-terminal domain 201 316 2.4E-27 T 06-07-2017 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal BWK49_RS09040 28691bbac8ad5561325db8f8891b7c7c 495 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 137 179 - T 06-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 BWK49_RS09040 28691bbac8ad5561325db8f8891b7c7c 495 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 322 459 8.0E-7 T 06-07-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 BWK49_RS09040 28691bbac8ad5561325db8f8891b7c7c 495 Gene3D G3DSA:3.30.310.20 202 316 3.1E-31 T 06-07-2017 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal BWK49_RS09040 28691bbac8ad5561325db8f8891b7c7c 495 SUPERFAMILY SSF46689 137 186 7.62E-8 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS09040 28691bbac8ad5561325db8f8891b7c7c 495 Pfam PF12833 Helix-turn-helix domain 106 185 1.5E-17 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 BWK49_RS09040 28691bbac8ad5561325db8f8891b7c7c 495 SUPERFAMILY SSF57884 2 82 3.27E-31 T 06-07-2017 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 BWK49_RS09040 28691bbac8ad5561325db8f8891b7c7c 495 Gene3D G3DSA:3.40.10.10 2 82 1.3E-33 T 06-07-2017 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 BWK49_RS09040 28691bbac8ad5561325db8f8891b7c7c 495 Pfam PF02805 Metal binding domain of Ada 8 71 8.5E-28 T 06-07-2017 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 BWK49_RS09040 28691bbac8ad5561325db8f8891b7c7c 495 Gene3D G3DSA:1.10.1670.10 434 487 5.3E-17 T 06-07-2017 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 BWK49_RS09040 28691bbac8ad5561325db8f8891b7c7c 495 SMART SM01009 201 316 6.6E-44 T 06-07-2017 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal BWK49_RS09040 28691bbac8ad5561325db8f8891b7c7c 495 Gene3D G3DSA:1.10.10.60 138 185 1.2E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS09040 28691bbac8ad5561325db8f8891b7c7c 495 SUPERFAMILY SSF55945 201 296 2.51E-22 T 06-07-2017 BWK49_RS05425 6c4f4fb691db9d108cc771cd3139befb 388 SUPERFAMILY SSF56349 179 375 7.95E-35 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 BWK49_RS05425 6c4f4fb691db9d108cc771cd3139befb 388 Gene3D G3DSA:1.10.150.130 27 124 9.4E-7 T 06-07-2017 IPR023109 Integrase/recombinase, N-terminal BWK49_RS05425 6c4f4fb691db9d108cc771cd3139befb 388 Gene3D G3DSA:1.10.443.10 179 374 4.3E-37 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 BWK49_RS05425 6c4f4fb691db9d108cc771cd3139befb 388 SUPERFAMILY SSF47823 28 86 1.84E-6 T 06-07-2017 IPR010998 Integrase, Lambda-type, N-terminal BWK49_RS05425 6c4f4fb691db9d108cc771cd3139befb 388 Pfam PF00589 Phage integrase family 180 366 3.0E-27 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 BWK49_RS14845 c37ef10293ce0bfa78c61ad7078a6cea 151 SUPERFAMILY SSF140736 12 148 6.15E-61 T 06-07-2017 BWK49_RS14845 c37ef10293ce0bfa78c61ad7078a6cea 151 Pfam PF08837 Protein of unknown function (DUF1810) 14 148 5.0E-59 T 06-07-2017 IPR014937 Protein of unknown function DUF1810 BWK49_RS14845 c37ef10293ce0bfa78c61ad7078a6cea 151 PIRSF PIRSF008546 9 150 1.6E-65 T 06-07-2017 IPR014937 Protein of unknown function DUF1810 BWK49_RS12815 9795b2b2d3a9beb9b7cf5df6ede7da94 367 Gene3D G3DSA:3.30.1360.120 145 237 1.6E-43 T 06-07-2017 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 BWK49_RS12815 9795b2b2d3a9beb9b7cf5df6ede7da94 367 Gene3D G3DSA:3.30.1360.120 10 58 1.6E-43 T 06-07-2017 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 BWK49_RS12815 9795b2b2d3a9beb9b7cf5df6ede7da94 367 PIRSF PIRSF006487 2 367 3.6E-83 T 06-07-2017 IPR028896 Aminomethyltransferase/Dimethylsulfonioproprionate demethylase DmdA KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 BWK49_RS12815 9795b2b2d3a9beb9b7cf5df6ede7da94 367 Hamap MF_00259 Aminomethyltransferase [gcvT]. 6 364 41.531 T 06-07-2017 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 BWK49_RS12815 9795b2b2d3a9beb9b7cf5df6ede7da94 367 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 9 362 8.1E-92 T 06-07-2017 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 BWK49_RS12815 9795b2b2d3a9beb9b7cf5df6ede7da94 367 Gene3D G3DSA:3.30.70.1400 59 144 1.4E-25 T 06-07-2017 BWK49_RS12815 9795b2b2d3a9beb9b7cf5df6ede7da94 367 SUPERFAMILY SSF101790 274 363 8.18E-25 T 06-07-2017 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain BWK49_RS12815 9795b2b2d3a9beb9b7cf5df6ede7da94 367 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 267 358 2.2E-23 T 06-07-2017 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 BWK49_RS12815 9795b2b2d3a9beb9b7cf5df6ede7da94 367 SUPERFAMILY SSF103025 7 281 4.55E-88 T 06-07-2017 BWK49_RS12815 9795b2b2d3a9beb9b7cf5df6ede7da94 367 Gene3D G3DSA:2.40.30.110 283 364 1.1E-25 T 06-07-2017 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 BWK49_RS12815 9795b2b2d3a9beb9b7cf5df6ede7da94 367 Pfam PF01571 Aminomethyltransferase folate-binding domain 12 260 1.8E-82 T 06-07-2017 IPR006222 Glycine cleavage T-protein-like, N-terminal BWK49_RS17530 3d3dceac527409b04f6a12acf1092b6b 1177 Pfam PF02811 PHP domain 8 194 2.9E-44 T 06-07-2017 IPR004013 PHP domain GO:0003824 BWK49_RS17530 3d3dceac527409b04f6a12acf1092b6b 1177 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 316 758 3.6E-158 T 06-07-2017 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 BWK49_RS17530 3d3dceac527409b04f6a12acf1092b6b 1177 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 6 1054 0.0 T 06-07-2017 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 BWK49_RS17530 3d3dceac527409b04f6a12acf1092b6b 1177 Pfam PF14579 Helix-hairpin-helix motif 831 918 2.8E-22 T 06-07-2017 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 BWK49_RS17530 3d3dceac527409b04f6a12acf1092b6b 1177 Gene3D G3DSA:3.20.20.140 6 274 1.6E-39 T 06-07-2017 BWK49_RS17530 3d3dceac527409b04f6a12acf1092b6b 1177 SUPERFAMILY SSF89550 120 268 1.24E-26 T 06-07-2017 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 BWK49_RS17530 3d3dceac527409b04f6a12acf1092b6b 1177 SUPERFAMILY SSF89550 6 92 1.24E-26 T 06-07-2017 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 BWK49_RS17530 3d3dceac527409b04f6a12acf1092b6b 1177 SMART SM00481 7 74 5.9E-32 T 06-07-2017 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 BWK49_RS18880 568351f90ff335e6af6e8b5bdb143d3e 196 ProSitePatterns PS01236 PdxT/SNO family family signature. 43 53 - T 06-07-2017 IPR021196 PdxT/SNO family, conserved site KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 BWK49_RS18880 568351f90ff335e6af6e8b5bdb143d3e 196 TIGRFAM TIGR03800 PLP_synth_Pdx2: pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2 5 192 2.7E-70 T 06-07-2017 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 BWK49_RS18880 568351f90ff335e6af6e8b5bdb143d3e 196 Hamap MF_01615 Pyridoxal 5'-phosphate synthase subunit PdxT [pdxT]. 6 193 37.186 T 06-07-2017 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 BWK49_RS18880 568351f90ff335e6af6e8b5bdb143d3e 196 SUPERFAMILY SSF52317 4 194 4.46E-48 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like BWK49_RS18880 568351f90ff335e6af6e8b5bdb143d3e 196 Pfam PF01174 SNO glutamine amidotransferase family 8 194 1.7E-57 T 06-07-2017 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 BWK49_RS18880 568351f90ff335e6af6e8b5bdb143d3e 196 PIRSF PIRSF005639 1 196 1.5E-72 T 06-07-2017 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 BWK49_RS18880 568351f90ff335e6af6e8b5bdb143d3e 196 Gene3D G3DSA:3.40.50.880 4 195 2.1E-72 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like BWK49_RS01735 15f83209db0a063e103e05a700ae18e5 334 Gene3D G3DSA:3.40.50.720 1 178 2.5E-37 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS01735 15f83209db0a063e103e05a700ae18e5 334 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 2 331 2.2E-47 T 06-07-2017 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0015940|GO:0016491|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 BWK49_RS01735 15f83209db0a063e103e05a700ae18e5 334 SUPERFAMILY SSF51735 1 118 1.2E-12 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS01735 15f83209db0a063e103e05a700ae18e5 334 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 181 329 1.1E-23 T 06-07-2017 IPR013752 Ketopantoate reductase, C-terminal domain GO:0016491|GO:0050661|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 BWK49_RS01735 15f83209db0a063e103e05a700ae18e5 334 SUPERFAMILY SSF48179 181 330 3.74E-15 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 BWK49_RS01735 15f83209db0a063e103e05a700ae18e5 334 Gene3D G3DSA:1.10.1040.10 181 329 2.8E-19 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 BWK49_RS01735 15f83209db0a063e103e05a700ae18e5 334 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 155 2.7E-28 T 06-07-2017 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 BWK49_RS06220 fe6dde0594fe81fb0b73c22b46114a12 363 Pfam PF04909 Amidohydrolase 14 354 1.9E-23 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 BWK49_RS06220 fe6dde0594fe81fb0b73c22b46114a12 363 SUPERFAMILY SSF51556 11 355 1.59E-53 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS06220 fe6dde0594fe81fb0b73c22b46114a12 363 Gene3D G3DSA:3.20.20.140 12 355 7.4E-41 T 06-07-2017 BWK49_RS21550 37d47250a54d54ebfcbabf2986d04d3f 364 SUPERFAMILY SSF54292 248 359 4.59E-27 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 BWK49_RS21550 37d47250a54d54ebfcbabf2986d04d3f 364 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 312 320 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 BWK49_RS21550 37d47250a54d54ebfcbabf2986d04d3f 364 Gene3D G3DSA:3.10.20.30 252 362 3.9E-29 T 06-07-2017 IPR012675 Beta-grasp domain BWK49_RS21550 37d47250a54d54ebfcbabf2986d04d3f 364 Pfam PF00970 Oxidoreductase FAD-binding domain 37 132 5.8E-10 T 06-07-2017 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 BWK49_RS21550 37d47250a54d54ebfcbabf2986d04d3f 364 PRINTS PR00410 Phenol hydroxylase reductase family signature 226 234 3.0E-9 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 BWK49_RS21550 37d47250a54d54ebfcbabf2986d04d3f 364 PRINTS PR00410 Phenol hydroxylase reductase family signature 127 136 3.0E-9 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 BWK49_RS21550 37d47250a54d54ebfcbabf2986d04d3f 364 PRINTS PR00410 Phenol hydroxylase reductase family signature 64 76 3.0E-9 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 BWK49_RS21550 37d47250a54d54ebfcbabf2986d04d3f 364 PRINTS PR00410 Phenol hydroxylase reductase family signature 142 161 3.0E-9 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 BWK49_RS21550 37d47250a54d54ebfcbabf2986d04d3f 364 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 83 90 2.0E-5 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 BWK49_RS21550 37d47250a54d54ebfcbabf2986d04d3f 364 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 142 161 2.0E-5 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 BWK49_RS21550 37d47250a54d54ebfcbabf2986d04d3f 364 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 64 74 2.0E-5 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 BWK49_RS21550 37d47250a54d54ebfcbabf2986d04d3f 364 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 226 234 2.0E-5 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 BWK49_RS21550 37d47250a54d54ebfcbabf2986d04d3f 364 SUPERFAMILY SSF52343 123 256 5.5E-31 T 06-07-2017 BWK49_RS21550 37d47250a54d54ebfcbabf2986d04d3f 364 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 282 355 2.3E-12 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 BWK49_RS21550 37d47250a54d54ebfcbabf2986d04d3f 364 SUPERFAMILY SSF63380 28 135 9.44E-26 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 BWK49_RS21550 37d47250a54d54ebfcbabf2986d04d3f 364 Gene3D G3DSA:3.40.50.80 126 251 1.5E-29 T 06-07-2017 BWK49_RS21550 37d47250a54d54ebfcbabf2986d04d3f 364 Pfam PF00175 Oxidoreductase NAD-binding domain 145 240 1.3E-13 T 06-07-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 BWK49_RS21550 37d47250a54d54ebfcbabf2986d04d3f 364 Gene3D G3DSA:2.40.30.10 31 125 8.4E-26 T 06-07-2017 BWK49_RS10080 a345d4150efcf7e466842636e20556e2 245 SUPERFAMILY SSF52266 5 91 1.03E-17 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain BWK49_RS10080 a345d4150efcf7e466842636e20556e2 245 SUPERFAMILY SSF52266 132 235 1.03E-17 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain BWK49_RS10080 a345d4150efcf7e466842636e20556e2 245 Gene3D G3DSA:3.40.50.1110 130 235 3.0E-12 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain BWK49_RS10080 a345d4150efcf7e466842636e20556e2 245 Gene3D G3DSA:3.40.50.1110 5 94 3.0E-12 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain BWK49_RS10080 a345d4150efcf7e466842636e20556e2 245 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 14 224 2.2E-8 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain BWK49_RS02405 ee6dc119b9fcf2509d8b95f5493bc264 400 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 343 352 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 BWK49_RS02405 ee6dc119b9fcf2509d8b95f5493bc264 400 SUPERFAMILY SSF48264 13 399 1.26E-84 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS02405 ee6dc119b9fcf2509d8b95f5493bc264 400 Gene3D G3DSA:1.10.630.10 11 399 9.3E-107 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS02405 ee6dc119b9fcf2509d8b95f5493bc264 400 PRINTS PR00385 P450 superfamily signature 350 361 8.1E-7 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS02405 ee6dc119b9fcf2509d8b95f5493bc264 400 PRINTS PR00385 P450 superfamily signature 240 257 8.1E-7 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS02405 ee6dc119b9fcf2509d8b95f5493bc264 400 PRINTS PR00385 P450 superfamily signature 341 350 8.1E-7 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS02405 ee6dc119b9fcf2509d8b95f5493bc264 400 PRINTS PR00385 P450 superfamily signature 275 286 8.1E-7 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS02405 ee6dc119b9fcf2509d8b95f5493bc264 400 PRINTS PR00359 B-class P450 signature 341 350 5.0E-40 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS02405 ee6dc119b9fcf2509d8b95f5493bc264 400 PRINTS PR00359 B-class P450 signature 87 98 5.0E-40 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS02405 ee6dc119b9fcf2509d8b95f5493bc264 400 PRINTS PR00359 B-class P450 signature 275 286 5.0E-40 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS02405 ee6dc119b9fcf2509d8b95f5493bc264 400 PRINTS PR00359 B-class P450 signature 133 149 5.0E-40 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS02405 ee6dc119b9fcf2509d8b95f5493bc264 400 PRINTS PR00359 B-class P450 signature 150 165 5.0E-40 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS02405 ee6dc119b9fcf2509d8b95f5493bc264 400 PRINTS PR00359 B-class P450 signature 189 211 5.0E-40 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS02405 ee6dc119b9fcf2509d8b95f5493bc264 400 PRINTS PR00359 B-class P450 signature 292 319 5.0E-40 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS02405 ee6dc119b9fcf2509d8b95f5493bc264 400 PRINTS PR00359 B-class P450 signature 320 335 5.0E-40 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS02405 ee6dc119b9fcf2509d8b95f5493bc264 400 PRINTS PR00359 B-class P450 signature 350 361 5.0E-40 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS02405 ee6dc119b9fcf2509d8b95f5493bc264 400 Pfam PF00067 Cytochrome P450 191 371 3.8E-20 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS27550 a527513bed0c87cbb4647d12b0e81a9d 295 Gene3D G3DSA:3.40.50.1820 6 293 3.4E-74 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS27550 a527513bed0c87cbb4647d12b0e81a9d 295 SUPERFAMILY SSF53474 7 293 4.59E-73 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS27550 a527513bed0c87cbb4647d12b0e81a9d 295 Pfam PF00561 alpha/beta hydrolase fold 34 139 1.6E-25 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS27550 a527513bed0c87cbb4647d12b0e81a9d 295 PRINTS PR00412 Epoxide hydrolase signature 269 291 9.0E-22 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS27550 a527513bed0c87cbb4647d12b0e81a9d 295 PRINTS PR00412 Epoxide hydrolase signature 236 252 9.0E-22 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS27550 a527513bed0c87cbb4647d12b0e81a9d 295 PRINTS PR00412 Epoxide hydrolase signature 60 75 9.0E-22 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS27550 a527513bed0c87cbb4647d12b0e81a9d 295 PRINTS PR00412 Epoxide hydrolase signature 40 58 9.0E-22 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS27550 a527513bed0c87cbb4647d12b0e81a9d 295 PRINTS PR00412 Epoxide hydrolase signature 104 117 9.0E-22 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS27550 a527513bed0c87cbb4647d12b0e81a9d 295 PRINTS PR00412 Epoxide hydrolase signature 118 131 9.0E-22 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS00685 c1fe7d5043d368043c229f0c44cc15d9 299 Pfam PF04072 Leucine carboxyl methyltransferase 19 200 1.7E-64 T 06-07-2017 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 BWK49_RS00685 c1fe7d5043d368043c229f0c44cc15d9 299 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 17 270 1.5E-84 T 06-07-2017 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 BWK49_RS00685 c1fe7d5043d368043c229f0c44cc15d9 299 Gene3D G3DSA:3.40.50.150 13 214 1.9E-19 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS00685 c1fe7d5043d368043c229f0c44cc15d9 299 SUPERFAMILY SSF53335 15 285 2.53E-76 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS13765 69e056e2c65d3824e38bed260e8b1827 441 SUPERFAMILY SSF53850 37 425 5.93E-65 T 06-07-2017 BWK49_RS13765 69e056e2c65d3824e38bed260e8b1827 441 Gene3D G3DSA:3.40.190.10 34 166 7.1E-18 T 06-07-2017 BWK49_RS13765 69e056e2c65d3824e38bed260e8b1827 441 Pfam PF01547 Bacterial extracellular solute-binding protein 45 352 6.4E-44 T 06-07-2017 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 BWK49_RS13765 69e056e2c65d3824e38bed260e8b1827 441 Gene3D G3DSA:3.40.190.10 167 372 1.2E-45 T 06-07-2017 BWK49_RS18600 170c1c3698701457c34837d33bf8e8ba 145 Pfam PF01478 Type IV leader peptidase family 8 109 2.2E-14 T 06-07-2017 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 BWK49_RS26430 1e97715e65cddaaecf2eb33a8cd1a955 96 Pfam PF06013 Proteins of 100 residues with WXG 3 88 2.4E-16 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like BWK49_RS26430 1e97715e65cddaaecf2eb33a8cd1a955 96 ProDom PD020150 ESAT-6-LIKE ANTIGEN ESXR CFP7 LOW WEIGHT ESXQ CFP-7 TB10.4 MOLECULAR 2 96 9.0E-48 T 06-07-2017 BWK49_RS26430 1e97715e65cddaaecf2eb33a8cd1a955 96 Gene3D G3DSA:1.10.287.1060 2 95 3.9E-20 T 06-07-2017 BWK49_RS26430 1e97715e65cddaaecf2eb33a8cd1a955 96 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 3 92 1.7E-16 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like BWK49_RS26430 1e97715e65cddaaecf2eb33a8cd1a955 96 SUPERFAMILY SSF140453 2 95 7.72E-21 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like BWK49_RS22025 e2d75e7331b567ce8e284efe5be0dfca 427 Pfam PF00146 NADH dehydrogenase 20 338 9.5E-123 T 06-07-2017 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS22025 e2d75e7331b567ce8e284efe5be0dfca 427 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 12 345 24.282 T 06-07-2017 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS22025 e2d75e7331b567ce8e284efe5be0dfca 427 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 222 235 - T 06-07-2017 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS22025 e2d75e7331b567ce8e284efe5be0dfca 427 ProSitePatterns PS00667 Respiratory-chain NADH dehydrogenase subunit 1 signature 1. 58 73 - T 06-07-2017 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS07265 ed0861d1c5e58fb370fd2b1e800080dc 395 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 10 293 1.9E-42 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS07265 ed0861d1c5e58fb370fd2b1e800080dc 395 Gene3D G3DSA:3.50.50.60 106 235 7.5E-20 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS07265 ed0861d1c5e58fb370fd2b1e800080dc 395 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 5.6E-10 T 06-07-2017 BWK49_RS07265 ed0861d1c5e58fb370fd2b1e800080dc 395 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 99 117 5.6E-10 T 06-07-2017 BWK49_RS07265 ed0861d1c5e58fb370fd2b1e800080dc 395 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 147 165 5.6E-10 T 06-07-2017 BWK49_RS07265 ed0861d1c5e58fb370fd2b1e800080dc 395 Gene3D G3DSA:3.50.50.60 8 105 2.2E-30 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS07265 ed0861d1c5e58fb370fd2b1e800080dc 395 Gene3D G3DSA:3.50.50.60 236 306 2.2E-30 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS07265 ed0861d1c5e58fb370fd2b1e800080dc 395 SUPERFAMILY SSF51905 6 289 6.2E-33 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS07265 ed0861d1c5e58fb370fd2b1e800080dc 395 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 143 167 5.4E-6 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 BWK49_RS07265 ed0861d1c5e58fb370fd2b1e800080dc 395 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 100 108 5.4E-6 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 BWK49_RS07265 ed0861d1c5e58fb370fd2b1e800080dc 395 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 199 215 5.4E-6 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 BWK49_RS07265 ed0861d1c5e58fb370fd2b1e800080dc 395 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 10 32 5.4E-6 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 BWK49_RS13620 9e749dd3aa15cfa48a488e910e0999db 408 PRINTS PR00359 B-class P450 signature 328 343 1.2E-39 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS13620 9e749dd3aa15cfa48a488e910e0999db 408 PRINTS PR00359 B-class P450 signature 350 359 1.2E-39 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS13620 9e749dd3aa15cfa48a488e910e0999db 408 PRINTS PR00359 B-class P450 signature 202 224 1.2E-39 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS13620 9e749dd3aa15cfa48a488e910e0999db 408 PRINTS PR00359 B-class P450 signature 359 370 1.2E-39 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS13620 9e749dd3aa15cfa48a488e910e0999db 408 PRINTS PR00359 B-class P450 signature 300 327 1.2E-39 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS13620 9e749dd3aa15cfa48a488e910e0999db 408 PRINTS PR00359 B-class P450 signature 141 157 1.2E-39 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS13620 9e749dd3aa15cfa48a488e910e0999db 408 PRINTS PR00359 B-class P450 signature 158 173 1.2E-39 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS13620 9e749dd3aa15cfa48a488e910e0999db 408 PRINTS PR00359 B-class P450 signature 95 106 1.2E-39 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS13620 9e749dd3aa15cfa48a488e910e0999db 408 PRINTS PR00359 B-class P450 signature 283 294 1.2E-39 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS13620 9e749dd3aa15cfa48a488e910e0999db 408 SUPERFAMILY SSF48264 34 406 5.89E-86 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS13620 9e749dd3aa15cfa48a488e910e0999db 408 Pfam PF00067 Cytochrome P450 93 373 3.4E-29 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS13620 9e749dd3aa15cfa48a488e910e0999db 408 Gene3D G3DSA:1.10.630.10 24 407 1.9E-102 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS13620 9e749dd3aa15cfa48a488e910e0999db 408 PRINTS PR00385 P450 superfamily signature 248 265 3.7E-6 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS13620 9e749dd3aa15cfa48a488e910e0999db 408 PRINTS PR00385 P450 superfamily signature 359 370 3.7E-6 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS13620 9e749dd3aa15cfa48a488e910e0999db 408 PRINTS PR00385 P450 superfamily signature 350 359 3.7E-6 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS13620 9e749dd3aa15cfa48a488e910e0999db 408 PRINTS PR00385 P450 superfamily signature 283 294 3.7E-6 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS13620 9e749dd3aa15cfa48a488e910e0999db 408 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 352 361 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 BWK49_RS02575 fdfa0afc833770ac91df3cce63c601f3 385 Gene3D G3DSA:3.90.1150.10 261 375 1.2E-7 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 BWK49_RS02575 fdfa0afc833770ac91df3cce63c601f3 385 TIGRFAM TIGR04343 egtE_PLP_lyase: ergothioneine biosynthesis PLP-dependent enzyme EgtE 7 376 3.8E-174 T 06-07-2017 IPR027563 Pyridoxal-phosphate-dependent protein EgtE BWK49_RS02575 fdfa0afc833770ac91df3cce63c601f3 385 Gene3D G3DSA:3.40.640.10 34 260 9.1E-41 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 BWK49_RS02575 fdfa0afc833770ac91df3cce63c601f3 385 SUPERFAMILY SSF53383 12 378 2.15E-56 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase BWK49_RS02575 fdfa0afc833770ac91df3cce63c601f3 385 Pfam PF00266 Aminotransferase class-V 23 371 2.6E-32 T 06-07-2017 IPR000192 Aminotransferase class V domain BWK49_RS02575 fdfa0afc833770ac91df3cce63c601f3 385 Hamap MF_02038 Probable hercynylcysteine sulfoxide lyase [egtE]. 5 377 35.815 T 06-07-2017 IPR027563 Pyridoxal-phosphate-dependent protein EgtE BWK49_RS12900 f6602a77b0c5400cf022db38e878bff1 284 SUPERFAMILY SSF46626 150 240 6.75E-22 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 BWK49_RS12900 f6602a77b0c5400cf022db38e878bff1 284 Pfam PF00034 Cytochrome c 68 140 1.3E-6 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 BWK49_RS12900 f6602a77b0c5400cf022db38e878bff1 284 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 167 239 3.1E-9 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 BWK49_RS12900 f6602a77b0c5400cf022db38e878bff1 284 SUPERFAMILY SSF46626 33 146 4.73E-18 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 BWK49_RS12900 f6602a77b0c5400cf022db38e878bff1 284 PIRSF PIRSF000007 3 284 4.1E-141 T 06-07-2017 IPR009152 Ubiquinol-cytochrome-c reductase, cytochrome c subunit GO:0005506|GO:0009055|GO:0016021|GO:0020037 BWK49_RS12900 f6602a77b0c5400cf022db38e878bff1 284 Gene3D G3DSA:1.10.760.10 64 149 3.1E-20 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 BWK49_RS12900 f6602a77b0c5400cf022db38e878bff1 284 Gene3D G3DSA:1.10.760.10 165 247 5.1E-15 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 BWK49_RS15735 216311b931d912a727cd00c55e3fa19c 281 Gene3D G3DSA:3.40.50.720 7 279 1.5E-76 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS15735 216311b931d912a727cd00c55e3fa19c 281 SUPERFAMILY SSF51735 7 280 1.49E-71 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS15735 216311b931d912a727cd00c55e3fa19c 281 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 159 187 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS15735 216311b931d912a727cd00c55e3fa19c 281 TIGRFAM TIGR03971 SDR_subfam_1: SDR family mycofactocin-dependent oxidoreductase 9 280 8.6E-114 T 06-07-2017 IPR023985 Mycofactocin-dependent oxidoreductase BWK49_RS15735 216311b931d912a727cd00c55e3fa19c 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 191 3.3E-33 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15735 216311b931d912a727cd00c55e3fa19c 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 146 162 3.3E-33 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15735 216311b931d912a727cd00c55e3fa19c 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 193 210 3.3E-33 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15735 216311b931d912a727cd00c55e3fa19c 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 3.3E-33 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15735 216311b931d912a727cd00c55e3fa19c 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 242 262 3.3E-33 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15735 216311b931d912a727cd00c55e3fa19c 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 99 110 3.3E-33 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15735 216311b931d912a727cd00c55e3fa19c 281 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 279 1.0E-49 T 06-07-2017 BWK49_RS15735 216311b931d912a727cd00c55e3fa19c 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 172 191 4.6E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15735 216311b931d912a727cd00c55e3fa19c 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 160 4.6E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15735 216311b931d912a727cd00c55e3fa19c 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 99 110 4.6E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS02380 5090fcb9d3b3d770e0d959b7bb09b0eb 356 Pfam PF04679 ATP dependent DNA ligase C terminal region 217 328 3.2E-15 T 06-07-2017 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 BWK49_RS02380 5090fcb9d3b3d770e0d959b7bb09b0eb 356 Gene3D G3DSA:2.40.50.140 200 334 4.7E-15 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS02380 5090fcb9d3b3d770e0d959b7bb09b0eb 356 SUPERFAMILY SSF56091 6 197 3.6E-42 T 06-07-2017 BWK49_RS02380 5090fcb9d3b3d770e0d959b7bb09b0eb 356 SUPERFAMILY SSF50249 200 336 4.45E-15 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS02380 5090fcb9d3b3d770e0d959b7bb09b0eb 356 Gene3D G3DSA:3.30.470.30 32 144 8.8E-28 T 06-07-2017 BWK49_RS02380 5090fcb9d3b3d770e0d959b7bb09b0eb 356 Gene3D G3DSA:3.30.1490.70 156 198 5.9E-11 T 06-07-2017 BWK49_RS02380 5090fcb9d3b3d770e0d959b7bb09b0eb 356 Gene3D G3DSA:3.30.1490.70 3 31 5.9E-11 T 06-07-2017 BWK49_RS02380 5090fcb9d3b3d770e0d959b7bb09b0eb 356 Pfam PF01068 ATP dependent DNA ligase domain 11 197 2.2E-38 T 06-07-2017 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 BWK49_RS04625 fb514482313c0a5c6df662d2134e6643 298 Pfam PF12146 Serine aminopeptidase, S33 26 128 1.6E-17 T 06-07-2017 IPR022742 Serine aminopeptidase, S33 BWK49_RS04625 fb514482313c0a5c6df662d2134e6643 298 Gene3D G3DSA:3.40.50.1820 3 292 1.2E-60 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS04625 fb514482313c0a5c6df662d2134e6643 298 SUPERFAMILY SSF53474 3 292 1.02E-46 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS21300 f2dc147962c7f7066f18e61e889fc7df 320 ProSitePatterns PS00368 Ribonucleotide reductase small subunit signature. 98 114 - T 06-07-2017 IPR030475 Ribonucleotide reductase small subunit, acitve site KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 BWK49_RS21300 f2dc147962c7f7066f18e61e889fc7df 320 SUPERFAMILY SSF47240 6 320 2.51E-106 T 06-07-2017 IPR009078 Ferritin-like superfamily BWK49_RS21300 f2dc147962c7f7066f18e61e889fc7df 320 Gene3D G3DSA:1.10.620.20 4 281 7.1E-95 T 06-07-2017 IPR012348 Ribonucleotide reductase-related GO:0016491|GO:0055114 Reactome: R-HSA-499943 BWK49_RS21300 f2dc147962c7f7066f18e61e889fc7df 320 TIGRFAM TIGR04171 RNR_1b_NrdF: ribonucleoside-diphosphate reductase, class 1b, beta subunit 8 320 5.5E-147 T 06-07-2017 IPR026494 Ribonucleoside reductase subunit beta, NrdF GO:0005971|GO:0009263 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 BWK49_RS21300 f2dc147962c7f7066f18e61e889fc7df 320 Pfam PF00268 Ribonucleotide reductase, small chain 10 281 1.8E-89 T 06-07-2017 IPR000358 Ribonucleotide reductase small subunit GO:0009186|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 BWK49_RS21300 f2dc147962c7f7066f18e61e889fc7df 320 PIRSF PIRSF000355 2 317 4.7E-80 T 06-07-2017 IPR000358 Ribonucleotide reductase small subunit GO:0009186|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 BWK49_RS23000 9d12012e96e30124b42da45316a11b5d 112 Pfam PF02467 Transcription factor WhiB 44 107 3.1E-27 T 06-07-2017 IPR003482 Transcription factor WhiB BWK49_RS23000 9d12012e96e30124b42da45316a11b5d 112 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 36 112 19.039 T 06-07-2017 IPR003482 Transcription factor WhiB BWK49_RS00350 e13c76b40c6b1617f3f0e702a56559ba 292 Pfam PF08044 Domain of unknown function (DUF1707) 17 69 3.0E-15 T 06-07-2017 IPR012551 Protein of unknown function DUF1707 BWK49_RS18715 5ce625b2cd4ed2edd904409f606c495a 265 SMART SM01007 37 215 1.9E-39 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal BWK49_RS18715 5ce625b2cd4ed2edd904409f606c495a 265 SUPERFAMILY SSF53639 32 240 5.1E-63 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal BWK49_RS18715 5ce625b2cd4ed2edd904409f606c495a 265 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 37 215 1.1E-36 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal BWK49_RS18715 5ce625b2cd4ed2edd904409f606c495a 265 Gene3D G3DSA:3.40.225.10 35 239 7.8E-52 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal BWK49_RS24735 a943751d7a38841c24b95428956848ee 161 PIRSF PIRSF021513 4 161 1.3E-67 T 06-07-2017 IPR016791 Rubromycin-type polyketide biosynthesis protein, GrhN/RubW, predicted BWK49_RS24735 a943751d7a38841c24b95428956848ee 161 Gene3D G3DSA:2.30.110.10 37 136 1.9E-4 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 BWK49_RS01550 4ef865e06e956b413ad03d9e6ef5c367 388 PIRSF PIRSF000429 5 386 9.0E-16 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 BWK49_RS01550 4ef865e06e956b413ad03d9e6ef5c367 388 Gene3D G3DSA:3.40.47.10 194 231 6.6E-14 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS01550 4ef865e06e956b413ad03d9e6ef5c367 388 Gene3D G3DSA:3.40.47.10 23 112 6.6E-14 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS01550 4ef865e06e956b413ad03d9e6ef5c367 388 SUPERFAMILY SSF53901 9 232 1.43E-18 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS01550 4ef865e06e956b413ad03d9e6ef5c367 388 Gene3D G3DSA:3.40.47.10 149 187 8.5E-13 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS01550 4ef865e06e956b413ad03d9e6ef5c367 388 Gene3D G3DSA:3.40.47.10 252 375 8.5E-13 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS01550 4ef865e06e956b413ad03d9e6ef5c367 388 SUPERFAMILY SSF53901 264 377 4.16E-20 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS01875 af724dbf1f508aad54692f3f813c6aa6 341 Gene3D G3DSA:3.40.50.720 165 281 2.0E-33 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS01875 af724dbf1f508aad54692f3f813c6aa6 341 Pfam PF00107 Zinc-binding dehydrogenase 171 300 8.7E-27 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 BWK49_RS01875 af724dbf1f508aad54692f3f813c6aa6 341 SMART SM00829 8 321 1.7E-8 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 BWK49_RS01875 af724dbf1f508aad54692f3f813c6aa6 341 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 129 1.0E-28 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 BWK49_RS01875 af724dbf1f508aad54692f3f813c6aa6 341 SUPERFAMILY SSF51735 137 302 1.79E-39 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS01875 af724dbf1f508aad54692f3f813c6aa6 341 Gene3D G3DSA:3.90.180.10 1 164 8.0E-53 T 06-07-2017 IPR011032 GroES-like BWK49_RS01875 af724dbf1f508aad54692f3f813c6aa6 341 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 58 72 - T 06-07-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 BWK49_RS01875 af724dbf1f508aad54692f3f813c6aa6 341 SUPERFAMILY SSF50129 1 168 4.56E-49 T 06-07-2017 IPR011032 GroES-like BWK49_RS19555 539841902cdf28c868b2ffc2969515e7 445 Pfam PF03993 Domain of Unknown Function (DUF349) 212 284 6.7E-20 T 06-07-2017 IPR007139 Protein of unknown function DUF349 BWK49_RS19555 539841902cdf28c868b2ffc2969515e7 445 Pfam PF03993 Domain of Unknown Function (DUF349) 289 361 2.1E-20 T 06-07-2017 IPR007139 Protein of unknown function DUF349 BWK49_RS19555 539841902cdf28c868b2ffc2969515e7 445 Pfam PF03993 Domain of Unknown Function (DUF349) 134 208 6.2E-12 T 06-07-2017 IPR007139 Protein of unknown function DUF349 BWK49_RS05045 fdb225db5214b454b33ec0765a079d5f 502 ProSitePatterns PS01173 Lipolytic enzymes "G-D-X-G" family, putative histidine active site. 103 118 - T 06-07-2017 IPR002168 Lipase, GDXG, putative histidine active site GO:0008152|GO:0016787 Reactome: R-HSA-163560 BWK49_RS05045 fdb225db5214b454b33ec0765a079d5f 502 Pfam PF00135 Carboxylesterase family 10 481 3.4E-89 T 06-07-2017 IPR002018 Carboxylesterase, type B BWK49_RS05045 fdb225db5214b454b33ec0765a079d5f 502 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 181 196 - T 06-07-2017 IPR019826 Carboxylesterase type B, active site BWK49_RS05045 fdb225db5214b454b33ec0765a079d5f 502 Gene3D G3DSA:3.40.50.1820 8 496 1.1E-118 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS05045 fdb225db5214b454b33ec0765a079d5f 502 ProSitePatterns PS00941 Carboxylesterases type-B signature 2. 82 92 - T 06-07-2017 IPR019819 Carboxylesterase type B, conserved site BWK49_RS05045 fdb225db5214b454b33ec0765a079d5f 502 SUPERFAMILY SSF53474 9 479 1.27E-106 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS02355 742d4a57748219c7220b949fbd655df0 301 PRINTS PR00111 Alpha/beta hydrolase fold signature 134 147 5.2E-12 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS02355 742d4a57748219c7220b949fbd655df0 301 PRINTS PR00111 Alpha/beta hydrolase fold signature 120 133 5.2E-12 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS02355 742d4a57748219c7220b949fbd655df0 301 PRINTS PR00111 Alpha/beta hydrolase fold signature 73 88 5.2E-12 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS02355 742d4a57748219c7220b949fbd655df0 301 Pfam PF00561 alpha/beta hydrolase fold 48 153 2.2E-22 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS02355 742d4a57748219c7220b949fbd655df0 301 PRINTS PR00412 Epoxide hydrolase signature 120 133 4.3E-17 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS02355 742d4a57748219c7220b949fbd655df0 301 PRINTS PR00412 Epoxide hydrolase signature 276 298 4.3E-17 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS02355 742d4a57748219c7220b949fbd655df0 301 PRINTS PR00412 Epoxide hydrolase signature 53 71 4.3E-17 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS02355 742d4a57748219c7220b949fbd655df0 301 PRINTS PR00412 Epoxide hydrolase signature 73 88 4.3E-17 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS02355 742d4a57748219c7220b949fbd655df0 301 Gene3D G3DSA:3.40.50.1820 18 300 1.4E-57 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS02355 742d4a57748219c7220b949fbd655df0 301 SUPERFAMILY SSF53474 16 301 1.41E-53 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS24005 c438d1118908b53d50216d617ddf4ac2 201 Gene3D G3DSA:1.10.1050.10 1 96 2.9E-38 T 06-07-2017 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 BWK49_RS24005 c438d1118908b53d50216d617ddf4ac2 201 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 201 3.0E-81 T 06-07-2017 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 BWK49_RS24005 c438d1118908b53d50216d617ddf4ac2 201 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 90 3.2E-26 T 06-07-2017 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 BWK49_RS24005 c438d1118908b53d50216d617ddf4ac2 201 SMART SM00363 91 153 1.7E-17 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 BWK49_RS24005 c438d1118908b53d50216d617ddf4ac2 201 ProSitePatterns PS00632 Ribosomal protein S4 signature. 89 113 - T 06-07-2017 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 BWK49_RS24005 c438d1118908b53d50216d617ddf4ac2 201 SMART SM01390 3 90 1.4E-42 T 06-07-2017 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 BWK49_RS24005 c438d1118908b53d50216d617ddf4ac2 201 Pfam PF01479 S4 domain 92 137 2.6E-17 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 BWK49_RS24005 c438d1118908b53d50216d617ddf4ac2 201 SUPERFAMILY SSF55174 3 201 1.44E-60 T 06-07-2017 BWK49_RS24005 c438d1118908b53d50216d617ddf4ac2 201 Gene3D G3DSA:3.10.290.10 97 185 4.9E-25 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 BWK49_RS24005 c438d1118908b53d50216d617ddf4ac2 201 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 201 33.81 T 06-07-2017 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 BWK49_RS10845 bba0858708d1a13987e91ed7a1342a9c 537 Gene3D G3DSA:3.40.50.980 199 311 7.8E-26 T 06-07-2017 BWK49_RS10845 bba0858708d1a13987e91ed7a1342a9c 537 Gene3D G3DSA:3.30.300.30 429 529 4.3E-23 T 06-07-2017 BWK49_RS10845 bba0858708d1a13987e91ed7a1342a9c 537 Pfam PF13193 AMP-binding enzyme C-terminal domain 443 520 3.6E-14 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS10845 bba0858708d1a13987e91ed7a1342a9c 537 SUPERFAMILY SSF56801 5 532 6.15E-125 T 06-07-2017 BWK49_RS10845 bba0858708d1a13987e91ed7a1342a9c 537 Gene3D G3DSA:2.30.38.10 354 424 1.4E-16 T 06-07-2017 BWK49_RS10845 bba0858708d1a13987e91ed7a1342a9c 537 Pfam PF00501 AMP-binding enzyme 16 433 3.7E-77 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS10845 bba0858708d1a13987e91ed7a1342a9c 537 ProSitePatterns PS00455 Putative AMP-binding domain signature. 194 205 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS10845 bba0858708d1a13987e91ed7a1342a9c 537 Gene3D G3DSA:3.40.50.980 9 198 1.3E-33 T 06-07-2017 BWK49_RS05535 b8a26660163939bd9393e7a60e3e5a76 92 SUPERFAMILY SSF46689 1 74 1.97E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS05535 b8a26660163939bd9393e7a60e3e5a76 92 Pfam PF01527 Transposase 2 75 6.1E-14 T 06-07-2017 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 BWK49_RS05535 b8a26660163939bd9393e7a60e3e5a76 92 Gene3D G3DSA:1.10.10.60 10 88 1.0E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS06395 c8a52fa4c8df266ca6fd98b10eaf89f0 200 SUPERFAMILY SSF46689 18 93 1.65E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS06395 c8a52fa4c8df266ca6fd98b10eaf89f0 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 71 3.5E-15 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS06395 c8a52fa4c8df266ca6fd98b10eaf89f0 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 2.4E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS06395 c8a52fa4c8df266ca6fd98b10eaf89f0 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 38 2.4E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS06395 c8a52fa4c8df266ca6fd98b10eaf89f0 200 Gene3D G3DSA:1.10.357.10 19 192 1.3E-26 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS27355 9ec8a5b3fc2a3d64a32d1b7eebd14fa0 250 Gene3D G3DSA:3.40.50.720 11 193 2.2E-49 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS27355 9ec8a5b3fc2a3d64a32d1b7eebd14fa0 250 SUPERFAMILY SSF51735 9 214 4.47E-48 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS27355 9ec8a5b3fc2a3d64a32d1b7eebd14fa0 250 Pfam PF00106 short chain dehydrogenase 14 187 5.8E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27355 9ec8a5b3fc2a3d64a32d1b7eebd14fa0 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 137 3.1E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27355 9ec8a5b3fc2a3d64a32d1b7eebd14fa0 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 166 3.1E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27355 9ec8a5b3fc2a3d64a32d1b7eebd14fa0 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 3.1E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27355 9ec8a5b3fc2a3d64a32d1b7eebd14fa0 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 3.1E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27355 9ec8a5b3fc2a3d64a32d1b7eebd14fa0 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 185 3.1E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27355 9ec8a5b3fc2a3d64a32d1b7eebd14fa0 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 147 166 1.0E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27355 9ec8a5b3fc2a3d64a32d1b7eebd14fa0 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 127 135 1.0E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27355 9ec8a5b3fc2a3d64a32d1b7eebd14fa0 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 1.0E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27355 9ec8a5b3fc2a3d64a32d1b7eebd14fa0 250 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 134 162 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS00115 595a9a25200cae16155df639b4a9b8f6 492 SUPERFAMILY SSF56601 98 490 7.68E-78 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like BWK49_RS00115 595a9a25200cae16155df639b4a9b8f6 492 Gene3D G3DSA:3.40.710.10 143 490 3.5E-86 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like BWK49_RS00115 595a9a25200cae16155df639b4a9b8f6 492 Gene3D G3DSA:3.90.1310.10 75 142 4.6E-5 T 06-07-2017 BWK49_RS00115 595a9a25200cae16155df639b4a9b8f6 492 Pfam PF00905 Penicillin binding protein transpeptidase domain 161 484 1.5E-74 T 06-07-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 BWK49_RS09945 4cd286453aa5382e49e07fec68f8cc8b 366 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 81 228 4.5E-30 T 06-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 BWK49_RS09945 4cd286453aa5382e49e07fec68f8cc8b 366 Gene3D G3DSA:3.40.50.970 47 268 4.8E-83 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS09945 4cd286453aa5382e49e07fec68f8cc8b 366 Gene3D G3DSA:3.40.50.970 312 351 4.8E-83 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS09945 4cd286453aa5382e49e07fec68f8cc8b 366 SUPERFAMILY SSF52518 9 365 1.25E-83 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS14145 b1c1b890b08eba2b48bfb3af53be332a 244 Pfam PF00005 ABC transporter 20 152 2.0E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 BWK49_RS14145 b1c1b890b08eba2b48bfb3af53be332a 244 ProSitePatterns PS00211 ABC transporters family signature. 125 139 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 BWK49_RS14145 b1c1b890b08eba2b48bfb3af53be332a 244 SMART SM00382 29 203 2.9E-17 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS14145 b1c1b890b08eba2b48bfb3af53be332a 244 Gene3D G3DSA:3.40.50.300 1 209 4.2E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS14145 b1c1b890b08eba2b48bfb3af53be332a 244 SUPERFAMILY SSF52540 2 213 9.2E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS22270 14d905636a4f17a1eddab547dc0902e3 719 SUPERFAMILY SSF51011 605 715 2.09E-26 T 06-07-2017 BWK49_RS22270 14d905636a4f17a1eddab547dc0902e3 719 SMART SM00642 181 581 2.0E-8 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 BWK49_RS22270 14d905636a4f17a1eddab547dc0902e3 719 Gene3D G3DSA:2.60.40.10 20 166 2.1E-60 T 06-07-2017 IPR013783 Immunoglobulin-like fold BWK49_RS22270 14d905636a4f17a1eddab547dc0902e3 719 Gene3D G3DSA:2.60.40.1180 605 715 4.6E-33 T 06-07-2017 IPR013780 Glycosyl hydrolase, all-beta BWK49_RS22270 14d905636a4f17a1eddab547dc0902e3 719 TIGRFAM TIGR02100 glgX_debranch: glycogen debranching enzyme GlgX 21 714 0.0 T 06-07-2017 IPR011837 Glycogen debranching enzyme, GlgX type GO:0004133|GO:0004553|GO:0005980 BWK49_RS22270 14d905636a4f17a1eddab547dc0902e3 719 SUPERFAMILY SSF51445 148 486 8.07E-132 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily BWK49_RS22270 14d905636a4f17a1eddab547dc0902e3 719 SUPERFAMILY SSF51445 515 589 8.07E-132 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily BWK49_RS22270 14d905636a4f17a1eddab547dc0902e3 719 SUPERFAMILY SSF81296 20 162 2.13E-48 T 06-07-2017 IPR014756 Immunoglobulin E-set BWK49_RS22270 14d905636a4f17a1eddab547dc0902e3 719 Gene3D G3DSA:3.20.20.80 167 589 1.6E-124 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 BWK49_RS22270 14d905636a4f17a1eddab547dc0902e3 719 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 25 111 2.8E-20 T 06-07-2017 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 BWK49_RS22270 14d905636a4f17a1eddab547dc0902e3 719 Pfam PF00128 Alpha amylase, catalytic domain 316 545 3.7E-5 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 BWK49_RS22270 14d905636a4f17a1eddab547dc0902e3 719 Pfam PF00128 Alpha amylase, catalytic domain 204 293 5.6E-10 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 BWK49_RS02750 98132c48eacf34a4d918602c8a24b072 116 Pfam PF02467 Transcription factor WhiB 31 93 2.2E-22 T 06-07-2017 IPR003482 Transcription factor WhiB BWK49_RS02750 98132c48eacf34a4d918602c8a24b072 116 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 20 98 17.059 T 06-07-2017 IPR003482 Transcription factor WhiB BWK49_RS02150 e12fd7eb4e22649404bc772061f6b245 212 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 185 3.9E-36 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 BWK49_RS02150 e12fd7eb4e22649404bc772061f6b245 212 SMART SM00855 2 150 5.5E-14 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 BWK49_RS02150 e12fd7eb4e22649404bc772061f6b245 212 Gene3D G3DSA:3.40.50.1240 1 191 5.6E-53 T 06-07-2017 IPR029033 Histidine phosphatase superfamily BWK49_RS02150 e12fd7eb4e22649404bc772061f6b245 212 SUPERFAMILY SSF53254 1 195 4.32E-38 T 06-07-2017 IPR029033 Histidine phosphatase superfamily BWK49_RS10195 bc785614368a6d5862bc7e688163c346 142 Pfam PF00571 CBS domain 71 123 9.7E-9 T 06-07-2017 IPR000644 CBS domain BWK49_RS10195 bc785614368a6d5862bc7e688163c346 142 Pfam PF00571 CBS domain 14 59 2.3E-10 T 06-07-2017 IPR000644 CBS domain BWK49_RS10195 bc785614368a6d5862bc7e688163c346 142 Gene3D G3DSA:3.10.580.10 1 126 2.9E-30 T 06-07-2017 BWK49_RS10195 bc785614368a6d5862bc7e688163c346 142 SUPERFAMILY SSF54631 1 140 7.58E-31 T 06-07-2017 BWK49_RS10195 bc785614368a6d5862bc7e688163c346 142 SMART SM00116 78 125 9.1E-6 T 06-07-2017 IPR000644 CBS domain BWK49_RS10195 bc785614368a6d5862bc7e688163c346 142 SMART SM00116 13 60 1.1E-6 T 06-07-2017 IPR000644 CBS domain BWK49_RS11010 eb4d1b2b9c93046ed9d8921ea07116c7 520 Pfam PF13193 AMP-binding enzyme C-terminal domain 433 509 4.3E-19 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS11010 eb4d1b2b9c93046ed9d8921ea07116c7 520 Gene3D G3DSA:2.30.38.10 346 418 4.4E-24 T 06-07-2017 BWK49_RS11010 eb4d1b2b9c93046ed9d8921ea07116c7 520 Gene3D G3DSA:3.30.300.30 419 518 2.1E-29 T 06-07-2017 BWK49_RS11010 eb4d1b2b9c93046ed9d8921ea07116c7 520 SUPERFAMILY SSF56801 8 519 2.09E-118 T 06-07-2017 BWK49_RS11010 eb4d1b2b9c93046ed9d8921ea07116c7 520 Gene3D G3DSA:3.40.50.980 8 183 1.2E-22 T 06-07-2017 BWK49_RS11010 eb4d1b2b9c93046ed9d8921ea07116c7 520 Gene3D G3DSA:3.40.50.980 184 345 2.0E-22 T 06-07-2017 BWK49_RS11010 eb4d1b2b9c93046ed9d8921ea07116c7 520 Pfam PF00501 AMP-binding enzyme 15 424 4.3E-74 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS13615 b8f0624ea21197d8e7d44eda94069b4d 869 Pfam PF00391 PEP-utilising enzyme, mobile domain 784 855 2.6E-20 T 06-07-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 BWK49_RS13615 b8f0624ea21197d8e7d44eda94069b4d 869 SUPERFAMILY SSF51735 2 277 1.79E-44 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS13615 b8f0624ea21197d8e7d44eda94069b4d 869 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 130 4.5E-20 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 BWK49_RS13615 b8f0624ea21197d8e7d44eda94069b4d 869 Gene3D G3DSA:3.40.50.720 2 275 2.0E-37 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS13615 b8f0624ea21197d8e7d44eda94069b4d 869 Gene3D G3DSA:3.50.30.10 777 861 2.3E-24 T 06-07-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 BWK49_RS13615 b8f0624ea21197d8e7d44eda94069b4d 869 SUPERFAMILY SSF52009 755 859 4.32E-25 T 06-07-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 BWK49_RS23765 8cc108338ba1c3c5bf853f5bf9772921 531 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 331 343 - T 06-07-2017 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 BWK49_RS23765 8cc108338ba1c3c5bf853f5bf9772921 531 PIRSF PIRSF000130 35 531 5.8E-200 T 06-07-2017 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-73817 BWK49_RS23765 8cc108338ba1c3c5bf853f5bf9772921 531 SUPERFAMILY SSF54631 129 239 6.82E-30 T 06-07-2017 BWK49_RS23765 8cc108338ba1c3c5bf853f5bf9772921 531 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 44 499 2.3E-179 T 06-07-2017 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-73817 BWK49_RS23765 8cc108338ba1c3c5bf853f5bf9772921 531 SMART SM01240 43 517 1.0E-301 T 06-07-2017 BWK49_RS23765 8cc108338ba1c3c5bf853f5bf9772921 531 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 44 517 1.7E-150 T 06-07-2017 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 BWK49_RS23765 8cc108338ba1c3c5bf853f5bf9772921 531 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 44 530 83.731 T 06-07-2017 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-73817 BWK49_RS23765 8cc108338ba1c3c5bf853f5bf9772921 531 SUPERFAMILY SSF51412 252 521 2.75E-112 T 06-07-2017 BWK49_RS23765 8cc108338ba1c3c5bf853f5bf9772921 531 SUPERFAMILY SSF51412 38 126 2.75E-112 T 06-07-2017 BWK49_RS23765 8cc108338ba1c3c5bf853f5bf9772921 531 Pfam PF00571 CBS domain 129 176 6.8E-9 T 06-07-2017 IPR000644 CBS domain BWK49_RS23765 8cc108338ba1c3c5bf853f5bf9772921 531 Pfam PF00571 CBS domain 185 238 1.1E-7 T 06-07-2017 IPR000644 CBS domain BWK49_RS23765 8cc108338ba1c3c5bf853f5bf9772921 531 Gene3D G3DSA:3.20.20.70 39 529 1.0E-188 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 BWK49_RS23765 8cc108338ba1c3c5bf853f5bf9772921 531 SMART SM00116 132 180 2.7E-7 T 06-07-2017 IPR000644 CBS domain BWK49_RS23765 8cc108338ba1c3c5bf853f5bf9772921 531 SMART SM00116 193 241 6.2E-7 T 06-07-2017 IPR000644 CBS domain BWK49_RS02385 ae80b10fefc392d968b4740ee47e7b84 343 TIGRFAM TIGR02778 ligD_pol: DNA ligase D, polymerase domain 14 263 1.8E-67 T 06-07-2017 IPR014145 DNA ligase D, polymerase domain BWK49_RS18105 e36bbcbf8cdcdb71cddb072670e06ced 164 Hamap MF_01400 Peptide methionine sulfoxide reductase MsrB [msrB]. 2 131 36.463 T 06-07-2017 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 BWK49_RS18105 e36bbcbf8cdcdb71cddb072670e06ced 164 Pfam PF01641 SelR domain 14 129 7.6E-50 T 06-07-2017 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 BWK49_RS18105 e36bbcbf8cdcdb71cddb072670e06ced 164 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 13 139 9.5E-60 T 06-07-2017 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 BWK49_RS18105 e36bbcbf8cdcdb71cddb072670e06ced 164 Gene3D G3DSA:2.170.150.20 12 146 3.1E-60 T 06-07-2017 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 BWK49_RS18105 e36bbcbf8cdcdb71cddb072670e06ced 164 SUPERFAMILY SSF51316 10 146 7.85E-59 T 06-07-2017 IPR011057 Mss4-like BWK49_RS08040 d1efc4e4e6f9c79bbcc64661f4f780cb 756 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 428 750 2.7E-154 T 06-07-2017 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 BWK49_RS08040 d1efc4e4e6f9c79bbcc64661f4f780cb 756 Hamap MF_00172 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [metE]. 6 755 34.576 T 06-07-2017 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 BWK49_RS08040 d1efc4e4e6f9c79bbcc64661f4f780cb 756 Gene3D G3DSA:3.20.20.210 391 754 5.1E-127 T 06-07-2017 BWK49_RS08040 d1efc4e4e6f9c79bbcc64661f4f780cb 756 PIRSF PIRSF000382 5 756 0.0 T 06-07-2017 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 BWK49_RS08040 d1efc4e4e6f9c79bbcc64661f4f780cb 756 SUPERFAMILY SSF51726 8 392 8.76E-95 T 06-07-2017 BWK49_RS08040 d1efc4e4e6f9c79bbcc64661f4f780cb 756 Pfam PF08267 Cobalamin-independent synthase, N-terminal domain 8 311 8.4E-113 T 06-07-2017 IPR013215 Cobalamin-independent methionine synthase MetE, N-terminal GO:0003871|GO:0008270|GO:0008652 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 BWK49_RS08040 d1efc4e4e6f9c79bbcc64661f4f780cb 756 TIGRFAM TIGR01371 met_syn_B12ind: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase 12 754 0.0 T 06-07-2017 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 BWK49_RS08040 d1efc4e4e6f9c79bbcc64661f4f780cb 756 SUPERFAMILY SSF51726 411 753 6.41E-115 T 06-07-2017 BWK49_RS08040 d1efc4e4e6f9c79bbcc64661f4f780cb 756 Gene3D G3DSA:3.20.20.210 7 387 1.5E-134 T 06-07-2017 BWK49_RS14995 2796b9cb4c332aba74f7e899d7a1f45b 139 SUPERFAMILY SSF46785 4 123 2.73E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS14995 2796b9cb4c332aba74f7e899d7a1f45b 139 Gene3D G3DSA:1.10.10.10 2 81 2.3E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS14995 2796b9cb4c332aba74f7e899d7a1f45b 139 PIRSF PIRSF019455 1 131 3.0E-22 T 06-07-2017 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 BWK49_RS14995 2796b9cb4c332aba74f7e899d7a1f45b 139 Pfam PF03965 Penicillinase repressor 7 120 8.4E-29 T 06-07-2017 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 BWK49_RS12460 42ed5f0523aab519c8709e903234209f 115 SUPERFAMILY SSF47336 3 109 2.36E-25 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS12460 42ed5f0523aab519c8709e903234209f 115 Pfam PF00550 Phosphopantetheine attachment site 12 77 3.2E-16 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS12460 42ed5f0523aab519c8709e903234209f 115 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 38 79 1.0E-16 T 06-07-2017 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS12460 42ed5f0523aab519c8709e903234209f 115 Gene3D G3DSA:1.10.1200.10 4 81 6.2E-26 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS12460 42ed5f0523aab519c8709e903234209f 115 Hamap MF_01217 Acyl carrier protein [acpP]. 7 81 17.605 T 06-07-2017 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS18430 abb0198a66ce1495f5378cc6c19a3b29 188 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 8 101 7.0E-11 T 06-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 BWK49_RS18430 abb0198a66ce1495f5378cc6c19a3b29 188 Gene3D G3DSA:2.30.110.10 7 130 4.7E-18 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 BWK49_RS18430 abb0198a66ce1495f5378cc6c19a3b29 188 SUPERFAMILY SSF50475 8 130 4.13E-13 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 BWK49_RS16895 5b704fb4666c756113c17c1af6bcd3d7 870 SUPERFAMILY SSF52743 503 526 1.96E-27 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 BWK49_RS16895 5b704fb4666c756113c17c1af6bcd3d7 870 SUPERFAMILY SSF52743 587 708 1.96E-27 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 BWK49_RS16895 5b704fb4666c756113c17c1af6bcd3d7 870 SUPERFAMILY SSF52743 304 473 1.96E-27 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 BWK49_RS16895 5b704fb4666c756113c17c1af6bcd3d7 870 Pfam PF00082 Subtilase family 351 666 5.5E-10 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 BWK49_RS16895 5b704fb4666c756113c17c1af6bcd3d7 870 Gene3D G3DSA:3.40.50.200 342 666 1.6E-13 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 BWK49_RS10340 a9c7c2efb70950e3b4dc881aab8fd8a2 704 Pfam PF00665 Integrase core domain 254 410 2.1E-11 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 BWK49_RS10340 a9c7c2efb70950e3b4dc881aab8fd8a2 704 SUPERFAMILY SSF53098 254 320 8.35E-17 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS10340 a9c7c2efb70950e3b4dc881aab8fd8a2 704 SUPERFAMILY SSF53098 361 485 8.35E-17 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS10340 a9c7c2efb70950e3b4dc881aab8fd8a2 704 Pfam PF09299 Mu transposase, C-terminal 504 564 1.4E-5 T 06-07-2017 IPR015378 Transposase-like, Mu, C-terminal BWK49_RS10340 a9c7c2efb70950e3b4dc881aab8fd8a2 704 Gene3D G3DSA:3.30.420.10 254 319 1.0E-22 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS10340 a9c7c2efb70950e3b4dc881aab8fd8a2 704 Gene3D G3DSA:3.30.420.10 358 486 1.0E-22 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS08535 e1c0bd85e823c876888feecd0b8b9999 504 Pfam PF13180 PDZ domain 416 498 1.4E-12 T 06-07-2017 IPR001478 PDZ domain GO:0005515 BWK49_RS08535 e1c0bd85e823c876888feecd0b8b9999 504 Gene3D G3DSA:2.40.10.10 299 418 5.1E-41 T 06-07-2017 BWK49_RS08535 e1c0bd85e823c876888feecd0b8b9999 504 Pfam PF13365 Trypsin-like peptidase domain 230 377 7.6E-35 T 06-07-2017 BWK49_RS08535 e1c0bd85e823c876888feecd0b8b9999 504 Gene3D G3DSA:2.30.42.10 419 501 9.2E-17 T 06-07-2017 IPR001478 PDZ domain GO:0005515 BWK49_RS08535 e1c0bd85e823c876888feecd0b8b9999 504 SUPERFAMILY SSF50156 397 499 2.5E-18 T 06-07-2017 IPR001478 PDZ domain GO:0005515 BWK49_RS08535 e1c0bd85e823c876888feecd0b8b9999 504 Gene3D G3DSA:2.40.10.10 203 293 2.7E-29 T 06-07-2017 BWK49_RS08535 e1c0bd85e823c876888feecd0b8b9999 504 PRINTS PR00834 HtrA/DegQ protease family signature 370 387 7.5E-44 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 BWK49_RS08535 e1c0bd85e823c876888feecd0b8b9999 504 PRINTS PR00834 HtrA/DegQ protease family signature 239 251 7.5E-44 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 BWK49_RS08535 e1c0bd85e823c876888feecd0b8b9999 504 PRINTS PR00834 HtrA/DegQ protease family signature 266 286 7.5E-44 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 BWK49_RS08535 e1c0bd85e823c876888feecd0b8b9999 504 PRINTS PR00834 HtrA/DegQ protease family signature 448 460 7.5E-44 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 BWK49_RS08535 e1c0bd85e823c876888feecd0b8b9999 504 PRINTS PR00834 HtrA/DegQ protease family signature 348 365 7.5E-44 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 BWK49_RS08535 e1c0bd85e823c876888feecd0b8b9999 504 PRINTS PR00834 HtrA/DegQ protease family signature 307 331 7.5E-44 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 BWK49_RS08535 e1c0bd85e823c876888feecd0b8b9999 504 SUPERFAMILY SSF50494 199 425 1.91E-55 T 06-07-2017 IPR009003 Peptidase S1, PA clan BWK49_RS08535 e1c0bd85e823c876888feecd0b8b9999 504 SMART SM00228 416 490 1.4E-4 T 06-07-2017 IPR001478 PDZ domain GO:0005515 BWK49_RS13915 ae4c8b8aec76ecc20eb33bc02274be10 308 Pfam PF07859 alpha/beta hydrolase fold 82 279 1.4E-56 T 06-07-2017 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 BWK49_RS13915 ae4c8b8aec76ecc20eb33bc02274be10 308 Gene3D G3DSA:3.40.50.1820 52 304 3.3E-70 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS13915 ae4c8b8aec76ecc20eb33bc02274be10 308 SUPERFAMILY SSF53474 44 304 2.89E-57 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS17900 906e38e4168f92fa3f2cd4a6a96b3152 478 Pfam PF00877 NlpC/P60 family 361 475 1.9E-30 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain BWK49_RS17900 906e38e4168f92fa3f2cd4a6a96b3152 478 SUPERFAMILY SSF54001 346 476 5.4E-31 T 06-07-2017 BWK49_RS17900 906e38e4168f92fa3f2cd4a6a96b3152 478 Gene3D G3DSA:3.90.1720.10 344 477 3.2E-37 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain BWK49_RS11445 1dea054dbecd9922beb789a9b8fcfaf4 177 SUPERFAMILY SSF55486 4 147 1.73E-38 T 06-07-2017 BWK49_RS11445 1dea054dbecd9922beb789a9b8fcfaf4 177 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 36 148 3.6E-32 T 06-07-2017 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 BWK49_RS11445 1dea054dbecd9922beb789a9b8fcfaf4 177 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 2 158 20.97 T 06-07-2017 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 BWK49_RS11445 1dea054dbecd9922beb789a9b8fcfaf4 177 Pfam PF02130 Uncharacterized protein family UPF0054 17 147 4.8E-36 T 06-07-2017 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 BWK49_RS11445 1dea054dbecd9922beb789a9b8fcfaf4 177 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 118 128 - T 06-07-2017 IPR020549 Endoribonuclease YbeY, conserved site BWK49_RS11445 1dea054dbecd9922beb789a9b8fcfaf4 177 Gene3D G3DSA:3.40.390.30 6 150 5.6E-42 T 06-07-2017 IPR023091 Metalloprotease catalytic domain, predicted GO:0004222 BWK49_RS23835 f83fe8e3b24ab1d3526a5f68b02e1b55 100 SMART SM00883 5 98 8.6E-56 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 BWK49_RS23835 f83fe8e3b24ab1d3526a5f68b02e1b55 100 Pfam PF00166 Chaperonin 10 Kd subunit 5 98 5.1E-35 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 BWK49_RS23835 f83fe8e3b24ab1d3526a5f68b02e1b55 100 SUPERFAMILY SSF50129 4 99 2.17E-35 T 06-07-2017 IPR011032 GroES-like BWK49_RS23835 f83fe8e3b24ab1d3526a5f68b02e1b55 100 Hamap MF_00580 10 kDa chaperonin [groS]. 5 99 25.61 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 BWK49_RS23835 f83fe8e3b24ab1d3526a5f68b02e1b55 100 PRINTS PR00297 10kDa chaperonin signature 64 76 1.5E-30 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 BWK49_RS23835 f83fe8e3b24ab1d3526a5f68b02e1b55 100 PRINTS PR00297 10kDa chaperonin signature 28 49 1.5E-30 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 BWK49_RS23835 f83fe8e3b24ab1d3526a5f68b02e1b55 100 PRINTS PR00297 10kDa chaperonin signature 6 21 1.5E-30 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 BWK49_RS23835 f83fe8e3b24ab1d3526a5f68b02e1b55 100 PRINTS PR00297 10kDa chaperonin signature 85 98 1.5E-30 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 BWK49_RS23835 f83fe8e3b24ab1d3526a5f68b02e1b55 100 Gene3D G3DSA:2.30.33.40 5 98 8.0E-38 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 BWK49_RS23835 f83fe8e3b24ab1d3526a5f68b02e1b55 100 ProSitePatterns PS00681 Chaperonins cpn10 signature. 6 30 - T 06-07-2017 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 BWK49_RS02810 337e4fbf8cfa04b1e8ed76df464a8391 323 Gene3D G3DSA:3.40.50.1820 6 316 1.4E-65 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS02810 337e4fbf8cfa04b1e8ed76df464a8391 323 PRINTS PR00412 Epoxide hydrolase signature 115 128 1.2E-10 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS02810 337e4fbf8cfa04b1e8ed76df464a8391 323 PRINTS PR00412 Epoxide hydrolase signature 289 311 1.2E-10 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS02810 337e4fbf8cfa04b1e8ed76df464a8391 323 PRINTS PR00412 Epoxide hydrolase signature 53 71 1.2E-10 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS02810 337e4fbf8cfa04b1e8ed76df464a8391 323 SUPERFAMILY SSF53474 14 314 4.51E-57 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS02810 337e4fbf8cfa04b1e8ed76df464a8391 323 Pfam PF12697 Alpha/beta hydrolase family 49 306 2.0E-19 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS19315 15bbb6707748c15de4afa039f2e45fe5 430 Pfam PF01612 3'-5' exonuclease 42 202 2.8E-33 T 06-07-2017 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 BWK49_RS19315 15bbb6707748c15de4afa039f2e45fe5 430 Pfam PF00570 HRDC domain 250 316 1.2E-14 T 06-07-2017 IPR002121 HRDC domain GO:0003676|GO:0005622 BWK49_RS19315 15bbb6707748c15de4afa039f2e45fe5 430 SMART SM00341 246 326 7.5E-24 T 06-07-2017 IPR002121 HRDC domain GO:0003676|GO:0005622 BWK49_RS19315 15bbb6707748c15de4afa039f2e45fe5 430 Gene3D G3DSA:3.30.420.10 53 205 2.1E-5 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS19315 15bbb6707748c15de4afa039f2e45fe5 430 SMART SM00474 32 203 2.3E-32 T 06-07-2017 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 BWK49_RS19315 15bbb6707748c15de4afa039f2e45fe5 430 SUPERFAMILY SSF47819 232 322 1.96E-22 T 06-07-2017 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 BWK49_RS19315 15bbb6707748c15de4afa039f2e45fe5 430 SUPERFAMILY SSF53098 38 244 1.33E-46 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS15420 45499fa4c18fb9e50b558d35de8ae7ab 234 PIRSF PIRSF001426 1 219 1.3E-84 T 06-07-2017 IPR023900 Nitrile hydratase alpha subunit /Thiocyanate hydrolase gamma subunit KEGG: 00364+4.2.1.84|KEGG: 00380+4.2.1.84|KEGG: 00627+4.2.1.84|KEGG: 00643+4.2.1.84|MetaCyc: PWY-5025|MetaCyc: PWY-581|MetaCyc: PWY-7308 BWK49_RS15420 45499fa4c18fb9e50b558d35de8ae7ab 234 ProDom PD007559 HYDRATASE NITRILE ALPHA SUBUNIT LYASE CHAIN METAL-BINDING DIRECT SEQUENCING NITRILASE 28 213 6.0E-70 T 06-07-2017 IPR004232 Nitrile hydratase alpha /Thiocyanate hydrolase gamma GO:0003824|GO:0006807|GO:0046914 KEGG: 00364+4.2.1.84|KEGG: 00380+4.2.1.84|KEGG: 00627+4.2.1.84|KEGG: 00643+4.2.1.84|MetaCyc: PWY-5025|MetaCyc: PWY-581|MetaCyc: PWY-7308 BWK49_RS15420 45499fa4c18fb9e50b558d35de8ae7ab 234 Gene3D G3DSA:3.90.330.10 4 219 5.8E-82 T 06-07-2017 IPR004232 Nitrile hydratase alpha /Thiocyanate hydrolase gamma GO:0003824|GO:0006807|GO:0046914 KEGG: 00364+4.2.1.84|KEGG: 00380+4.2.1.84|KEGG: 00627+4.2.1.84|KEGG: 00643+4.2.1.84|MetaCyc: PWY-5025|MetaCyc: PWY-581|MetaCyc: PWY-7308 BWK49_RS15420 45499fa4c18fb9e50b558d35de8ae7ab 234 TIGRFAM TIGR03887 thiocyan_alph: thiocyanate hydrolase, gamma subunit 17 216 8.1E-118 T 06-07-2017 IPR023901 Thiocyanate hydrolase, gamma subunit MetaCyc: PWY-743 BWK49_RS15420 45499fa4c18fb9e50b558d35de8ae7ab 234 SUPERFAMILY SSF56209 9 213 1.11E-70 T 06-07-2017 IPR004232 Nitrile hydratase alpha /Thiocyanate hydrolase gamma GO:0003824|GO:0006807|GO:0046914 KEGG: 00364+4.2.1.84|KEGG: 00380+4.2.1.84|KEGG: 00627+4.2.1.84|KEGG: 00643+4.2.1.84|MetaCyc: PWY-5025|MetaCyc: PWY-581|MetaCyc: PWY-7308 BWK49_RS15420 45499fa4c18fb9e50b558d35de8ae7ab 234 Pfam PF02979 Nitrile hydratase, alpha chain 21 211 8.6E-70 T 06-07-2017 IPR004232 Nitrile hydratase alpha /Thiocyanate hydrolase gamma GO:0003824|GO:0006807|GO:0046914 KEGG: 00364+4.2.1.84|KEGG: 00380+4.2.1.84|KEGG: 00627+4.2.1.84|KEGG: 00643+4.2.1.84|MetaCyc: PWY-5025|MetaCyc: PWY-581|MetaCyc: PWY-7308 BWK49_RS27780 b4976b11962cb74377a80c695b980e60 397 Gene3D G3DSA:3.30.1540.10 225 297 2.1E-19 T 06-07-2017 BWK49_RS27780 b4976b11962cb74377a80c695b980e60 397 SUPERFAMILY SSF89796 1 377 4.06E-116 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS27780 b4976b11962cb74377a80c695b980e60 397 Gene3D G3DSA:3.40.50.10540 1 211 2.5E-101 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS27780 b4976b11962cb74377a80c695b980e60 397 Gene3D G3DSA:3.40.50.10540 298 377 2.5E-101 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS27780 b4976b11962cb74377a80c695b980e60 397 Pfam PF02515 CoA-transferase family III 1 364 4.4E-113 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 BWK49_RS24690 6ae8536987f29e2aa29536b1db31a04c 1100 Pfam PF04257 Exodeoxyribonuclease V, gamma subunit 3 749 1.3E-199 T 06-07-2017 BWK49_RS24690 6ae8536987f29e2aa29536b1db31a04c 1100 Hamap MF_01486 RecBCD enzyme subunit RecC [recC]. 2 1099 15.92 T 06-07-2017 IPR006697 RecBCD enzyme subunit RecC GO:0008854|GO:0009338 BWK49_RS24690 6ae8536987f29e2aa29536b1db31a04c 1100 Gene3D G3DSA:1.10.10.160 91 192 3.0E-20 T 06-07-2017 IPR013986 DExx box DNA helicase domain BWK49_RS24690 6ae8536987f29e2aa29536b1db31a04c 1100 PIRSF PIRSF000980 2 1090 0.0 T 06-07-2017 IPR006697 RecBCD enzyme subunit RecC GO:0008854|GO:0009338 BWK49_RS24690 6ae8536987f29e2aa29536b1db31a04c 1100 SUPERFAMILY SSF52540 321 768 3.29E-71 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS24690 6ae8536987f29e2aa29536b1db31a04c 1100 SUPERFAMILY SSF52980 783 1096 5.9E-66 T 06-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 BWK49_RS24690 6ae8536987f29e2aa29536b1db31a04c 1100 SUPERFAMILY SSF52540 3 319 2.83E-76 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS24690 6ae8536987f29e2aa29536b1db31a04c 1100 TIGRFAM TIGR01450 recC: exodeoxyribonuclease V, gamma subunit 3 1048 1.8E-304 T 06-07-2017 IPR006697 RecBCD enzyme subunit RecC GO:0008854|GO:0009338 BWK49_RS21475 7f23824b6d0f25e2b4eea860c096c3df 268 Pfam PF00106 short chain dehydrogenase 10 205 1.4E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS21475 7f23824b6d0f25e2b4eea860c096c3df 268 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 174 193 3.0E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS21475 7f23824b6d0f25e2b4eea860c096c3df 268 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 144 152 3.0E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS21475 7f23824b6d0f25e2b4eea860c096c3df 268 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 91 102 3.0E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS21475 7f23824b6d0f25e2b4eea860c096c3df 268 Gene3D G3DSA:3.40.50.720 6 244 2.2E-59 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS21475 7f23824b6d0f25e2b4eea860c096c3df 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 193 2.0E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS21475 7f23824b6d0f25e2b4eea860c096c3df 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 91 102 2.0E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS21475 7f23824b6d0f25e2b4eea860c096c3df 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 138 154 2.0E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS21475 7f23824b6d0f25e2b4eea860c096c3df 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 195 212 2.0E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS21475 7f23824b6d0f25e2b4eea860c096c3df 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 2.0E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS21475 7f23824b6d0f25e2b4eea860c096c3df 268 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 161 189 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS21475 7f23824b6d0f25e2b4eea860c096c3df 268 SUPERFAMILY SSF51735 5 250 5.98E-56 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS05965 1f74e5172b97de2f007ba4b90a582492 280 Pfam PF02709 N-terminal domain of galactosyltransferase 168 202 1.9E-5 T 06-07-2017 IPR027791 Galactosyltransferase, C-terminal BWK49_RS05965 1f74e5172b97de2f007ba4b90a582492 280 SUPERFAMILY SSF53448 3 126 2.73E-27 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases BWK49_RS05965 1f74e5172b97de2f007ba4b90a582492 280 SUPERFAMILY SSF53448 159 257 2.73E-27 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases BWK49_RS05965 1f74e5172b97de2f007ba4b90a582492 280 Gene3D G3DSA:3.90.550.10 2 223 6.8E-19 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases BWK49_RS23630 36d5a5cc1ede6ab038a15776fee51f2d 671 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 369 553 1.5E-4 T 06-07-2017 BWK49_RS23630 36d5a5cc1ede6ab038a15776fee51f2d 671 SUPERFAMILY SSF51735 365 586 4.8E-59 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS23630 36d5a5cc1ede6ab038a15776fee51f2d 671 SUPERFAMILY SSF51735 1 283 1.19E-44 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS23630 36d5a5cc1ede6ab038a15776fee51f2d 671 Gene3D G3DSA:3.40.50.720 368 594 4.2E-58 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS23630 36d5a5cc1ede6ab038a15776fee51f2d 671 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 493 509 8.3E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS23630 36d5a5cc1ede6ab038a15776fee51f2d 671 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 519 538 8.3E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS23630 36d5a5cc1ede6ab038a15776fee51f2d 671 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 370 387 8.3E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS23630 36d5a5cc1ede6ab038a15776fee51f2d 671 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 444 455 8.3E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS23630 36d5a5cc1ede6ab038a15776fee51f2d 671 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 519 538 1.6E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS23630 36d5a5cc1ede6ab038a15776fee51f2d 671 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 499 507 1.6E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS23630 36d5a5cc1ede6ab038a15776fee51f2d 671 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 444 455 1.6E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS23630 36d5a5cc1ede6ab038a15776fee51f2d 671 Pfam PF07993 Male sterility protein 5 231 3.2E-41 T 06-07-2017 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 BWK49_RS23630 36d5a5cc1ede6ab038a15776fee51f2d 671 Pfam PF00106 short chain dehydrogenase 370 557 1.1E-45 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS23630 36d5a5cc1ede6ab038a15776fee51f2d 671 Gene3D G3DSA:3.40.50.720 1 277 4.4E-41 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS04990 f102cdf5c03bd0961fa9b582a5752a71 317 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 2.8E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS04990 f102cdf5c03bd0961fa9b582a5752a71 317 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 2.8E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS04990 f102cdf5c03bd0961fa9b582a5752a71 317 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 2.8E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS04990 f102cdf5c03bd0961fa9b582a5752a71 317 SUPERFAMILY SSF51735 4 277 7.12E-70 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS04990 f102cdf5c03bd0961fa9b582a5752a71 317 Pfam PF00106 short chain dehydrogenase 10 195 1.6E-55 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS04990 f102cdf5c03bd0961fa9b582a5752a71 317 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS04990 f102cdf5c03bd0961fa9b582a5752a71 317 Gene3D G3DSA:3.40.50.720 9 247 2.8E-71 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS04990 f102cdf5c03bd0961fa9b582a5752a71 317 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 1.2E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS04990 f102cdf5c03bd0961fa9b582a5752a71 317 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 1.2E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS04990 f102cdf5c03bd0961fa9b582a5752a71 317 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 1.2E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS04990 f102cdf5c03bd0961fa9b582a5752a71 317 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 1.2E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS04990 f102cdf5c03bd0961fa9b582a5752a71 317 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 1.2E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS29015 9b8eab3ac732bac279e06df3d374e00b 530 Pfam PF11203 Putative type VII ESX secretion system translocon, EccE 180 272 6.1E-17 T 06-07-2017 IPR021368 Type VII secretion system protein EccE BWK49_RS29015 9b8eab3ac732bac279e06df3d374e00b 530 TIGRFAM TIGR03923 T7SS_EccE: type VII secretion protein EccE 15 347 2.0E-70 T 06-07-2017 IPR021368 Type VII secretion system protein EccE BWK49_RS03730 00289dcca98960ca4c8b9ab2b6a3352f 260 Pfam PF05305 Protein of unknown function (DUF732) 137 220 9.6E-16 T 06-07-2017 IPR007969 Domain of unknown function DUF732 BWK49_RS28435 aae588d8dceda86c571187a66d7fa081 447 Gene3D G3DSA:1.20.1250.20 226 398 2.0E-14 T 06-07-2017 BWK49_RS28435 aae588d8dceda86c571187a66d7fa081 447 Gene3D G3DSA:1.20.1250.20 12 183 7.1E-16 T 06-07-2017 BWK49_RS28435 aae588d8dceda86c571187a66d7fa081 447 SUPERFAMILY SSF103473 10 400 6.02E-38 T 06-07-2017 IPR020846 Major facilitator superfamily domain BWK49_RS28435 aae588d8dceda86c571187a66d7fa081 447 Pfam PF07690 Major Facilitator Superfamily 12 321 7.1E-22 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 BWK49_RS14590 86fa1a0c4c6871c862756d19d13eae1a 522 Gene3D G3DSA:3.50.50.60 194 195 3.6E-32 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS14590 86fa1a0c4c6871c862756d19d13eae1a 522 Gene3D G3DSA:3.50.50.60 2 59 3.6E-32 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS14590 86fa1a0c4c6871c862756d19d13eae1a 522 Gene3D G3DSA:3.50.50.60 231 308 3.6E-32 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS14590 86fa1a0c4c6871c862756d19d13eae1a 522 Gene3D G3DSA:3.50.50.60 100 101 3.6E-32 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS14590 86fa1a0c4c6871c862756d19d13eae1a 522 SUPERFAMILY SSF51905 1 304 7.62E-42 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS14590 86fa1a0c4c6871c862756d19d13eae1a 522 SUPERFAMILY SSF51905 467 497 7.62E-42 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS14590 86fa1a0c4c6871c862756d19d13eae1a 522 Pfam PF01593 Flavin containing amine oxidoreductase 17 326 1.7E-11 T 06-07-2017 IPR002937 Amine oxidase GO:0016491|GO:0055114 BWK49_RS22640 528741145b751fb06ba7b2950150097e 356 Gene3D G3DSA:1.10.287.70 40 135 3.5E-15 T 06-07-2017 BWK49_RS22640 528741145b751fb06ba7b2950150097e 356 SUPERFAMILY SSF81324 29 164 4.45E-23 T 06-07-2017 BWK49_RS22640 528741145b751fb06ba7b2950150097e 356 Pfam PF02254 TrkA-N domain 151 267 3.4E-26 T 06-07-2017 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 BWK49_RS22640 528741145b751fb06ba7b2950150097e 356 Pfam PF07885 Ion channel 47 130 9.4E-15 T 06-07-2017 IPR013099 Potassium channel domain BWK49_RS22640 528741145b751fb06ba7b2950150097e 356 SUPERFAMILY SSF51735 146 290 5.25E-28 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS22640 528741145b751fb06ba7b2950150097e 356 Gene3D G3DSA:3.40.50.720 143 279 1.7E-35 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS22960 f6c199f04bbe9152fb19e03bb216f618 415 Pfam PF00487 Fatty acid desaturase 134 353 7.8E-35 T 06-07-2017 IPR005804 Fatty acid desaturase domain GO:0006629 BWK49_RS22935 e1bf37d621da0129d133158548dfae26 210 SUPERFAMILY SSF52540 2 197 3.11E-28 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS22935 e1bf37d621da0129d133158548dfae26 210 Pfam PF02223 Thymidylate kinase 5 166 9.5E-20 T 06-07-2017 BWK49_RS22935 e1bf37d621da0129d133158548dfae26 210 ProSitePatterns PS01331 Thymidylate kinase signature. 92 104 - T 06-07-2017 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 BWK49_RS22935 e1bf37d621da0129d133158548dfae26 210 Gene3D G3DSA:3.40.50.300 1 203 2.1E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS16000 f83f9ff79f3bd2ddd4352d6af176bce8 518 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 253 260 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 BWK49_RS16000 f83f9ff79f3bd2ddd4352d6af176bce8 518 SUPERFAMILY SSF53720 30 482 3.67E-139 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 BWK49_RS16000 f83f9ff79f3bd2ddd4352d6af176bce8 518 Gene3D G3DSA:3.40.309.10 268 445 9.6E-62 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 BWK49_RS16000 f83f9ff79f3bd2ddd4352d6af176bce8 518 Pfam PF00171 Aldehyde dehydrogenase family 24 481 1.4E-139 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 BWK49_RS16000 f83f9ff79f3bd2ddd4352d6af176bce8 518 Gene3D G3DSA:3.40.605.10 28 267 3.3E-68 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 BWK49_RS11765 9b9000ee38b7dbbe672a57acab409756 591 Pfam PF07969 Amidohydrolase family 44 207 1.0E-9 T 06-07-2017 IPR013108 Amidohydrolase 3 BWK49_RS11765 9b9000ee38b7dbbe672a57acab409756 591 Gene3D G3DSA:2.30.40.10 479 557 1.5E-11 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 BWK49_RS11765 9b9000ee38b7dbbe672a57acab409756 591 SUPERFAMILY SSF51556 56 315 1.84E-36 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS11765 9b9000ee38b7dbbe672a57acab409756 591 SUPERFAMILY SSF51556 363 494 1.84E-36 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS11765 9b9000ee38b7dbbe672a57acab409756 591 SUPERFAMILY SSF51338 474 559 4.32E-5 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 BWK49_RS11765 9b9000ee38b7dbbe672a57acab409756 591 Gene3D G3DSA:3.20.20.140 418 478 5.7E-73 T 06-07-2017 BWK49_RS11765 9b9000ee38b7dbbe672a57acab409756 591 Gene3D G3DSA:3.20.20.140 70 307 5.7E-73 T 06-07-2017 BWK49_RS11765 9b9000ee38b7dbbe672a57acab409756 591 SUPERFAMILY SSF51338 3 71 1.04E-17 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 BWK49_RS11765 9b9000ee38b7dbbe672a57acab409756 591 Gene3D G3DSA:2.30.40.10 3 69 2.8E-17 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 BWK49_RS18410 a2d2a8926bd622b1efa377fcf4091cbb 321 Gene3D G3DSA:3.40.50.1820 9 319 1.6E-88 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS18410 a2d2a8926bd622b1efa377fcf4091cbb 321 SUPERFAMILY SSF53474 32 318 9.39E-65 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS18410 a2d2a8926bd622b1efa377fcf4091cbb 321 ProSitePatterns PS01173 Lipolytic enzymes "G-D-X-G" family, putative histidine active site. 88 104 - T 06-07-2017 IPR002168 Lipase, GDXG, putative histidine active site GO:0008152|GO:0016787 Reactome: R-HSA-163560 BWK49_RS18410 a2d2a8926bd622b1efa377fcf4091cbb 321 ProSitePatterns PS01174 Lipolytic enzymes "G-D-X-G" family, putative serine active site. 160 172 - T 06-07-2017 IPR033140 Lipase, GDXG, putative serine active site BWK49_RS18410 a2d2a8926bd622b1efa377fcf4091cbb 321 Pfam PF07859 alpha/beta hydrolase fold 88 295 4.6E-67 T 06-07-2017 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 BWK49_RS24945 f3be03e8beaea040895106bf9dd3fd77 363 SUPERFAMILY SSF50129 313 361 2.21E-5 T 06-07-2017 IPR011032 GroES-like BWK49_RS24945 f3be03e8beaea040895106bf9dd3fd77 363 Pfam PF00107 Zinc-binding dehydrogenase 191 317 6.0E-25 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 BWK49_RS24945 f3be03e8beaea040895106bf9dd3fd77 363 SMART SM00829 12 361 1.5E-5 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 BWK49_RS24945 f3be03e8beaea040895106bf9dd3fd77 363 Gene3D G3DSA:3.40.50.720 184 304 5.8E-37 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS24945 f3be03e8beaea040895106bf9dd3fd77 363 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 110 6.8E-25 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 BWK49_RS24945 f3be03e8beaea040895106bf9dd3fd77 363 Gene3D G3DSA:3.90.180.10 4 183 3.9E-53 T 06-07-2017 IPR011032 GroES-like BWK49_RS24945 f3be03e8beaea040895106bf9dd3fd77 363 SUPERFAMILY SSF51735 152 328 3.85E-41 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS24945 f3be03e8beaea040895106bf9dd3fd77 363 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 60 74 - T 06-07-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 BWK49_RS24945 f3be03e8beaea040895106bf9dd3fd77 363 SUPERFAMILY SSF50129 3 187 5.33E-51 T 06-07-2017 IPR011032 GroES-like BWK49_RS28120 1161743b48cb6116fb6f6990b06f6c2d 778 Gene3D G3DSA:3.30.1540.10 227 294 2.0E-17 T 06-07-2017 BWK49_RS28120 1161743b48cb6116fb6f6990b06f6c2d 778 SUPERFAMILY SSF89796 378 771 3.4E-97 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS28120 1161743b48cb6116fb6f6990b06f6c2d 778 Gene3D G3DSA:3.30.1540.10 605 679 2.1E-14 T 06-07-2017 BWK49_RS28120 1161743b48cb6116fb6f6990b06f6c2d 778 SUPERFAMILY SSF89796 6 361 1.83E-64 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS28120 1161743b48cb6116fb6f6990b06f6c2d 778 Pfam PF02515 CoA-transferase family III 8 358 2.3E-59 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 BWK49_RS28120 1161743b48cb6116fb6f6990b06f6c2d 778 Pfam PF02515 CoA-transferase family III 380 747 1.2E-93 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 BWK49_RS28120 1161743b48cb6116fb6f6990b06f6c2d 778 Gene3D G3DSA:3.40.50.10540 295 360 5.8E-51 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS28120 1161743b48cb6116fb6f6990b06f6c2d 778 Gene3D G3DSA:3.40.50.10540 5 208 5.8E-51 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS28120 1161743b48cb6116fb6f6990b06f6c2d 778 Gene3D G3DSA:3.40.50.10540 377 595 8.2E-89 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS28120 1161743b48cb6116fb6f6990b06f6c2d 778 Gene3D G3DSA:3.40.50.10540 680 772 8.2E-89 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS25775 2c40c67284c9934eb266a3c4b12684bd 275 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 16 269 8.9E-85 T 06-07-2017 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 BWK49_RS25775 2c40c67284c9934eb266a3c4b12684bd 275 SUPERFAMILY SSF53613 15 272 1.12E-72 T 06-07-2017 IPR029056 Ribokinase-like BWK49_RS25775 2c40c67284c9934eb266a3c4b12684bd 275 Gene3D G3DSA:3.40.1190.20 15 269 1.5E-91 T 06-07-2017 IPR029056 Ribokinase-like BWK49_RS25775 2c40c67284c9934eb266a3c4b12684bd 275 Pfam PF08543 Phosphomethylpyrimidine kinase 23 268 3.6E-86 T 06-07-2017 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-964975 BWK49_RS09825 9e7978abbc61c004b951a1ac340de4c7 1616 PIRSF PIRSF036761 1 1611 0.0 T 06-07-2017 IPR007780 NAD-glutamate dehydrogenase, bacteria GO:0004352|GO:0019551 KEGG: 00220+1.4.1.2|KEGG: 00250+1.4.1.2|KEGG: 00430+1.4.1.2|KEGG: 00910+1.4.1.2|MetaCyc: PWY-5022|MetaCyc: PWY-6728|MetaCyc: PWY-7126 BWK49_RS09825 9e7978abbc61c004b951a1ac340de4c7 1616 Gene3D G3DSA:3.40.50.720 942 1053 2.2E-35 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS09825 9e7978abbc61c004b951a1ac340de4c7 1616 Gene3D G3DSA:3.40.50.720 1093 1185 2.2E-35 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS09825 9e7978abbc61c004b951a1ac340de4c7 1616 SUPERFAMILY SSF51735 1088 1215 1.64E-25 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS09825 9e7978abbc61c004b951a1ac340de4c7 1616 SUPERFAMILY SSF51735 945 1047 1.64E-25 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS09825 9e7978abbc61c004b951a1ac340de4c7 1616 SUPERFAMILY SSF53223 761 956 1.92E-21 T 06-07-2017 BWK49_RS09825 9e7978abbc61c004b951a1ac340de4c7 1616 Pfam PF05088 Bacterial NAD-glutamate dehydrogenase 97 1604 0.0 T 06-07-2017 IPR028971 NAD-glutamate dehydrogenase GO:0004352|GO:0019551 KEGG: 00220+1.4.1.2|KEGG: 00250+1.4.1.2|KEGG: 00430+1.4.1.2|KEGG: 00910+1.4.1.2|MetaCyc: PWY-5022|MetaCyc: PWY-6728|MetaCyc: PWY-7126 BWK49_RS20220 3bbb96e0594629d492d07c6a06edd639 386 Gene3D G3DSA:3.20.20.70 25 384 5.8E-123 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 BWK49_RS20220 3bbb96e0594629d492d07c6a06edd639 386 Pfam PF01070 FMN-dependent dehydrogenase 33 383 2.9E-112 T 06-07-2017 IPR000262 FMN-dependent dehydrogenase GO:0016491 BWK49_RS20220 3bbb96e0594629d492d07c6a06edd639 386 SUPERFAMILY SSF51395 25 382 9.94E-89 T 06-07-2017 BWK49_RS20220 3bbb96e0594629d492d07c6a06edd639 386 PIRSF PIRSF000138 5 386 2.1E-115 T 06-07-2017 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 BWK49_RS11760 00b7b65fb21e55a4da0c47e2cf846935 260 Gene3D G3DSA:3.40.50.720 3 255 3.7E-84 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS11760 00b7b65fb21e55a4da0c47e2cf846935 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 5.0E-14 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS11760 00b7b65fb21e55a4da0c47e2cf846935 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 5.0E-14 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS11760 00b7b65fb21e55a4da0c47e2cf846935 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 5.0E-14 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS11760 00b7b65fb21e55a4da0c47e2cf846935 260 SUPERFAMILY SSF51735 7 240 9.43E-78 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS11760 00b7b65fb21e55a4da0c47e2cf846935 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 8.5E-45 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS11760 00b7b65fb21e55a4da0c47e2cf846935 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 8.5E-45 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS11760 00b7b65fb21e55a4da0c47e2cf846935 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 202 222 8.5E-45 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS11760 00b7b65fb21e55a4da0c47e2cf846935 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 8.5E-45 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS11760 00b7b65fb21e55a4da0c47e2cf846935 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 8.5E-45 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS11760 00b7b65fb21e55a4da0c47e2cf846935 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 8.5E-45 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS11760 00b7b65fb21e55a4da0c47e2cf846935 260 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 239 2.5E-65 T 06-07-2017 BWK49_RS11760 00b7b65fb21e55a4da0c47e2cf846935 260 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS11810 929ce5d450b9b9dbaa40fa157623c6de 217 SUPERFAMILY SSF46689 20 101 2.69E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS11810 929ce5d450b9b9dbaa40fa157623c6de 217 Gene3D G3DSA:1.10.357.10 22 195 1.1E-33 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS11810 929ce5d450b9b9dbaa40fa157623c6de 217 Pfam PF00440 Bacterial regulatory proteins, tetR family 33 79 3.2E-13 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS11810 929ce5d450b9b9dbaa40fa157623c6de 217 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 46 2.1E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS11810 929ce5d450b9b9dbaa40fa157623c6de 217 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 54 77 2.1E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS11810 929ce5d450b9b9dbaa40fa157623c6de 217 SUPERFAMILY SSF48498 101 207 9.24E-8 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS12325 050afa4a0bfb0f5ee766dff75d40b1da 389 Gene3D G3DSA:1.10.540.10 12 109 1.1E-33 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS12325 050afa4a0bfb0f5ee766dff75d40b1da 389 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 235 366 3.1E-31 T 06-07-2017 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain BWK49_RS12325 050afa4a0bfb0f5ee766dff75d40b1da 389 Gene3D G3DSA:1.20.140.10 197 384 2.1E-37 T 06-07-2017 BWK49_RS12325 050afa4a0bfb0f5ee766dff75d40b1da 389 Gene3D G3DSA:2.40.110.10 116 196 8.4E-30 T 06-07-2017 BWK49_RS12325 050afa4a0bfb0f5ee766dff75d40b1da 389 PIRSF PIRSF016578 1 388 1.1E-123 T 06-07-2017 BWK49_RS12325 050afa4a0bfb0f5ee766dff75d40b1da 389 SUPERFAMILY SSF56645 14 203 2.75E-34 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS12325 050afa4a0bfb0f5ee766dff75d40b1da 389 SUPERFAMILY SSF47203 226 360 1.2E-10 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS12240 c0a722538c4e0dcd08856741deabaf42 194 SUPERFAMILY SSF46689 4 69 1.13E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS12240 c0a722538c4e0dcd08856741deabaf42 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 9.1E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS12240 c0a722538c4e0dcd08856741deabaf42 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 9.1E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS12240 c0a722538c4e0dcd08856741deabaf42 194 Gene3D G3DSA:1.10.357.10 66 192 1.0E-42 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS12240 c0a722538c4e0dcd08856741deabaf42 194 SUPERFAMILY SSF48498 83 192 1.29E-29 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS12240 c0a722538c4e0dcd08856741deabaf42 194 Gene3D G3DSA:1.10.10.60 6 61 1.9E-21 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS12240 c0a722538c4e0dcd08856741deabaf42 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 61 1.2E-16 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS25785 3d9aed2c1f06bfc7561e78465de5130f 144 SMART SM00347 27 128 5.9E-18 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 BWK49_RS25785 3d9aed2c1f06bfc7561e78465de5130f 144 Gene3D G3DSA:1.10.287.100 98 143 5.0E-18 T 06-07-2017 IPR013028 Transcription factor IIA, alpha subunit, N-terminal GO:0006367 BWK49_RS25785 3d9aed2c1f06bfc7561e78465de5130f 144 Pfam PF01047 MarR family 34 90 4.2E-13 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 BWK49_RS25785 3d9aed2c1f06bfc7561e78465de5130f 144 SUPERFAMILY SSF46785 13 141 2.21E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS25785 3d9aed2c1f06bfc7561e78465de5130f 144 Gene3D G3DSA:1.10.10.10 33 97 7.1E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS20065 dc96539595f4eb36214c6cd74a7e3577 604 Pfam PF00905 Penicillin binding protein transpeptidase domain 327 582 2.6E-38 T 06-07-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 BWK49_RS20065 dc96539595f4eb36214c6cd74a7e3577 604 Gene3D G3DSA:3.90.1310.10 269 312 0.001 T 06-07-2017 BWK49_RS20065 dc96539595f4eb36214c6cd74a7e3577 604 SUPERFAMILY SSF56601 307 596 3.38E-56 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like BWK49_RS20065 dc96539595f4eb36214c6cd74a7e3577 604 Pfam PF05223 NTF2-like N-terminal transpeptidase domain 32 139 3.4E-21 T 06-07-2017 IPR007887 NTF2-like N-terminal transpeptidase GO:0046677 BWK49_RS20065 dc96539595f4eb36214c6cd74a7e3577 604 Gene3D G3DSA:3.40.710.10 313 597 4.3E-56 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like BWK49_RS27015 904c229171a6df7bcaf7277ede0c0b89 375 Gene3D G3DSA:1.20.140.10 209 371 2.6E-63 T 06-07-2017 BWK49_RS27015 904c229171a6df7bcaf7277ede0c0b89 375 Gene3D G3DSA:2.40.110.10 111 208 6.7E-31 T 06-07-2017 BWK49_RS27015 904c229171a6df7bcaf7277ede0c0b89 375 SUPERFAMILY SSF56645 1 233 5.63E-67 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS27015 904c229171a6df7bcaf7277ede0c0b89 375 PIRSF PIRSF016578 6 373 6.5E-18 T 06-07-2017 BWK49_RS27015 904c229171a6df7bcaf7277ede0c0b89 375 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 1 107 5.4E-30 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS27015 904c229171a6df7bcaf7277ede0c0b89 375 SUPERFAMILY SSF47203 221 371 1.39E-53 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS27015 904c229171a6df7bcaf7277ede0c0b89 375 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 112 207 9.3E-26 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 BWK49_RS27015 904c229171a6df7bcaf7277ede0c0b89 375 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 221 369 6.7E-48 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS27015 904c229171a6df7bcaf7277ede0c0b89 375 Gene3D G3DSA:1.10.540.10 1 108 2.5E-34 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS01530 591165c59d32af566aa68c0f130e18bb 447 Gene3D G3DSA:2.102.10.10 48 151 7.3E-22 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS01530 591165c59d32af566aa68c0f130e18bb 447 ProSitePatterns PS00570 Bacterial ring hydroxylating dioxygenases alpha-subunit signature. 91 114 - T 06-07-2017 IPR015881 Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site GO:0005506|GO:0016705|GO:0051537|GO:0055114 BWK49_RS01530 591165c59d32af566aa68c0f130e18bb 447 SUPERFAMILY SSF50022 25 164 6.94E-44 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS01530 591165c59d32af566aa68c0f130e18bb 447 Pfam PF00355 Rieske [2Fe-2S] domain 48 132 3.0E-21 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS01530 591165c59d32af566aa68c0f130e18bb 447 Gene3D G3DSA:3.90.380.10 152 443 4.9E-97 T 06-07-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 BWK49_RS01530 591165c59d32af566aa68c0f130e18bb 447 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 169 438 5.9E-23 T 06-07-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 BWK49_RS01530 591165c59d32af566aa68c0f130e18bb 447 SUPERFAMILY SSF55961 166 440 7.14E-62 T 06-07-2017 BWK49_RS01530 591165c59d32af566aa68c0f130e18bb 447 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 105 125 2.4E-42 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS01530 591165c59d32af566aa68c0f130e18bb 447 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 33 58 2.4E-42 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS01530 591165c59d32af566aa68c0f130e18bb 447 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 63 78 2.4E-42 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS01530 591165c59d32af566aa68c0f130e18bb 447 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 84 104 2.4E-42 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS01530 591165c59d32af566aa68c0f130e18bb 447 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 190 212 2.4E-42 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS01530 591165c59d32af566aa68c0f130e18bb 447 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 149 175 2.4E-42 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS09650 dfaa3ceafa2b4d8c38d04b61ba40bd2a 579 Pfam PF12077 Transmembrane protein of unknown function (DUF3556) 1 571 1.8E-268 T 06-07-2017 IPR021941 Protein of unknown function DUF3556, transmembrane BWK49_RS03140 ace488db96273c504609061f9f1dc6d9 303 Gene3D G3DSA:1.10.1670.10 134 227 3.9E-32 T 06-07-2017 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 BWK49_RS03140 ace488db96273c504609061f9f1dc6d9 303 SUPERFAMILY SSF48150 19 220 2.98E-60 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 BWK49_RS03140 ace488db96273c504609061f9f1dc6d9 303 Pfam PF00633 Helix-hairpin-helix motif 111 139 5.7E-8 T 06-07-2017 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 BWK49_RS03140 ace488db96273c504609061f9f1dc6d9 303 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 46 159 1.0E-15 T 06-07-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 BWK49_RS03140 ace488db96273c504609061f9f1dc6d9 303 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 203 215 6.0E-4 T 06-07-2017 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 BWK49_RS03140 ace488db96273c504609061f9f1dc6d9 303 Gene3D G3DSA:1.10.340.30 32 133 1.6E-35 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 BWK49_RS03140 ace488db96273c504609061f9f1dc6d9 303 SMART SM00478 50 201 2.2E-45 T 06-07-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 BWK49_RS21420 d209b6e11d8b72c3baf504dce7c8ac73 509 Pfam PF04679 ATP dependent DNA ligase C terminal region 401 494 1.1E-11 T 06-07-2017 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 BWK49_RS21420 d209b6e11d8b72c3baf504dce7c8ac73 509 Hamap MF_00407 DNA ligase [lig]. 1 509 26.746 T 06-07-2017 IPR022865 DNA ligase, ATP-dependent, bacterial/archaeal GO:0003910 BWK49_RS21420 d209b6e11d8b72c3baf504dce7c8ac73 509 Gene3D G3DSA:1.10.3260.10 71 185 2.5E-19 T 06-07-2017 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 BWK49_RS21420 d209b6e11d8b72c3baf504dce7c8ac73 509 ProSitePatterns PS00697 ATP-dependent DNA ligase AMP-binding site. 211 219 - T 06-07-2017 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 BWK49_RS21420 d209b6e11d8b72c3baf504dce7c8ac73 509 SUPERFAMILY SSF50249 384 509 2.06E-31 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS21420 d209b6e11d8b72c3baf504dce7c8ac73 509 SUPERFAMILY SSF56091 182 382 1.22E-43 T 06-07-2017 BWK49_RS21420 d209b6e11d8b72c3baf504dce7c8ac73 509 ProSitePatterns PS00333 ATP-dependent DNA ligase signature 2. 358 382 - T 06-07-2017 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 BWK49_RS21420 d209b6e11d8b72c3baf504dce7c8ac73 509 Gene3D G3DSA:3.30.1490.70 186 215 9.7E-19 T 06-07-2017 BWK49_RS21420 d209b6e11d8b72c3baf504dce7c8ac73 509 Gene3D G3DSA:3.30.1490.70 334 381 9.7E-19 T 06-07-2017 BWK49_RS21420 d209b6e11d8b72c3baf504dce7c8ac73 509 Gene3D G3DSA:2.40.50.140 385 509 7.0E-35 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS21420 d209b6e11d8b72c3baf504dce7c8ac73 509 SUPERFAMILY SSF117018 5 201 1.57E-29 T 06-07-2017 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 BWK49_RS21420 d209b6e11d8b72c3baf504dce7c8ac73 509 Pfam PF04675 DNA ligase N terminus 68 139 6.4E-8 T 06-07-2017 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 BWK49_RS21420 d209b6e11d8b72c3baf504dce7c8ac73 509 Pfam PF01068 ATP dependent DNA ligase domain 188 382 1.3E-46 T 06-07-2017 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 BWK49_RS21420 d209b6e11d8b72c3baf504dce7c8ac73 509 TIGRFAM TIGR00574 dnl1: DNA ligase I, ATP-dependent (dnl1) 72 509 2.0E-82 T 06-07-2017 IPR000977 DNA ligase, ATP-dependent GO:0003910|GO:0005524|GO:0006281|GO:0006310|GO:0071897 BWK49_RS21420 d209b6e11d8b72c3baf504dce7c8ac73 509 Gene3D G3DSA:3.30.470.30 216 332 2.2E-27 T 06-07-2017 BWK49_RS16585 b7ea6440bfff42169f31895bca269e57 341 Pfam PF00589 Phage integrase family 166 313 2.9E-20 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 BWK49_RS16585 b7ea6440bfff42169f31895bca269e57 341 Gene3D G3DSA:1.10.150.130 29 109 4.2E-9 T 06-07-2017 IPR023109 Integrase/recombinase, N-terminal BWK49_RS16585 b7ea6440bfff42169f31895bca269e57 341 SUPERFAMILY SSF56349 29 319 4.71E-42 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 BWK49_RS16585 b7ea6440bfff42169f31895bca269e57 341 Gene3D G3DSA:1.10.443.10 158 318 1.7E-29 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 BWK49_RS20730 35d52c173c63ccb213f1ba442db85af0 160 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 20 41 3.2E-52 T 06-07-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 BWK49_RS20730 35d52c173c63ccb213f1ba442db85af0 160 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 2 20 3.2E-52 T 06-07-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 BWK49_RS20730 35d52c173c63ccb213f1ba442db85af0 160 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 49 73 3.2E-52 T 06-07-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 BWK49_RS20730 35d52c173c63ccb213f1ba442db85af0 160 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 85 101 3.2E-52 T 06-07-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 BWK49_RS20730 35d52c173c63ccb213f1ba442db85af0 160 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 111 133 3.2E-52 T 06-07-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 BWK49_RS20730 35d52c173c63ccb213f1ba442db85af0 160 Gene3D G3DSA:3.40.50.620 4 156 2.7E-53 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold BWK49_RS20730 35d52c173c63ccb213f1ba442db85af0 160 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 2 157 33.264 T 06-07-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 BWK49_RS20730 35d52c173c63ccb213f1ba442db85af0 160 Pfam PF01467 Cytidylyltransferase-like 6 131 2.2E-20 T 06-07-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 BWK49_RS20730 35d52c173c63ccb213f1ba442db85af0 160 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 4 155 1.2E-59 T 06-07-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 BWK49_RS20730 35d52c173c63ccb213f1ba442db85af0 160 ProDom PD016147 LIGASE LYASE CITRATE PRO-3S-LYASE SYNTHETASE TRANSFERASE CYTIDYLTRANSFERASE-RELATED:CITRATE ACETATE:SH-CITRATE CITC PLASMID 11 156 0.005 T 06-07-2017 BWK49_RS20730 35d52c173c63ccb213f1ba442db85af0 160 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 4 62 1.7E-17 T 06-07-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 BWK49_RS20730 35d52c173c63ccb213f1ba442db85af0 160 SUPERFAMILY SSF52374 4 155 1.21E-44 T 06-07-2017 BWK49_RS11005 204a3bfefcf6067b952b8dba12fea12e 400 SUPERFAMILY SSF56645 12 249 3.4E-58 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS11005 204a3bfefcf6067b952b8dba12fea12e 400 Gene3D G3DSA:1.10.540.10 13 127 1.2E-16 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS11005 204a3bfefcf6067b952b8dba12fea12e 400 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 131 213 5.6E-21 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 BWK49_RS11005 204a3bfefcf6067b952b8dba12fea12e 400 Gene3D G3DSA:2.40.110.10 130 227 2.0E-28 T 06-07-2017 BWK49_RS11005 204a3bfefcf6067b952b8dba12fea12e 400 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 14 125 7.6E-16 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS11005 204a3bfefcf6067b952b8dba12fea12e 400 Gene3D G3DSA:1.20.140.10 228 399 1.4E-26 T 06-07-2017 BWK49_RS11005 204a3bfefcf6067b952b8dba12fea12e 400 SUPERFAMILY SSF47203 238 395 8.57E-18 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS11005 204a3bfefcf6067b952b8dba12fea12e 400 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 238 393 1.7E-22 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS24440 81970d083c190db8f994fac0c914c2cd 214 SUPERFAMILY SSF48498 99 203 8.15E-20 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS24440 81970d083c190db8f994fac0c914c2cd 214 Gene3D G3DSA:1.10.357.10 78 204 1.2E-32 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS24440 81970d083c190db8f994fac0c914c2cd 214 Pfam PF00440 Bacterial regulatory proteins, tetR family 31 77 7.3E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS24440 81970d083c190db8f994fac0c914c2cd 214 Pfam PF13305 WHG domain 105 182 4.0E-12 T 06-07-2017 IPR025996 WHG domain BWK49_RS24440 81970d083c190db8f994fac0c914c2cd 214 SUPERFAMILY SSF46689 21 89 4.77E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS24440 81970d083c190db8f994fac0c914c2cd 214 Gene3D G3DSA:1.10.10.60 16 77 1.1E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS28145 bb04691886e0c36220aaf503424821e6 741 SUPERFAMILY SSF56645 369 605 1.44E-52 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS28145 bb04691886e0c36220aaf503424821e6 741 SUPERFAMILY SSF47203 595 738 9.42E-13 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS28145 bb04691886e0c36220aaf503424821e6 741 Gene3D G3DSA:1.10.540.10 1 100 5.6E-11 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS28145 bb04691886e0c36220aaf503424821e6 741 Gene3D G3DSA:1.20.140.10 226 337 1.8E-23 T 06-07-2017 BWK49_RS28145 bb04691886e0c36220aaf503424821e6 741 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 488 582 7.6E-20 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 BWK49_RS28145 bb04691886e0c36220aaf503424821e6 741 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 98 1.7E-8 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS28145 bb04691886e0c36220aaf503424821e6 741 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 376 483 7.6E-5 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS28145 bb04691886e0c36220aaf503424821e6 741 Gene3D G3DSA:1.10.540.10 360 484 6.1E-7 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS28145 bb04691886e0c36220aaf503424821e6 741 Gene3D G3DSA:1.20.140.10 583 741 8.0E-21 T 06-07-2017 BWK49_RS28145 bb04691886e0c36220aaf503424821e6 741 SUPERFAMILY SSF47203 225 356 1.39E-24 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS28145 bb04691886e0c36220aaf503424821e6 741 Gene3D G3DSA:2.40.110.10 487 582 1.1E-31 T 06-07-2017 BWK49_RS28145 bb04691886e0c36220aaf503424821e6 741 SUPERFAMILY SSF56645 1 208 1.44E-19 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS28145 bb04691886e0c36220aaf503424821e6 741 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 595 735 1.6E-10 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS28145 bb04691886e0c36220aaf503424821e6 741 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 225 339 4.1E-14 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS24255 86798111da1cfa28d8b1c3b1aeb41424 105 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 38 105 7.0E-24 T 06-07-2017 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS24255 86798111da1cfa28d8b1c3b1aeb41424 105 Gene3D G3DSA:2.30.30.30 1 90 6.2E-27 T 06-07-2017 IPR014722 Ribosomal protein L2 domain 2 BWK49_RS24255 86798111da1cfa28d8b1c3b1aeb41424 105 SUPERFAMILY SSF50104 1 102 2.14E-30 T 06-07-2017 IPR008991 Translation protein SH3-like domain BWK49_RS24255 86798111da1cfa28d8b1c3b1aeb41424 105 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 1 105 8.2E-38 T 06-07-2017 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS24255 86798111da1cfa28d8b1c3b1aeb41424 105 SMART SM00739 2 29 3.9E-6 T 06-07-2017 IPR005824 KOW BWK49_RS24255 86798111da1cfa28d8b1c3b1aeb41424 105 ProSitePatterns PS01108 Ribosomal protein L24 signature. 6 23 - T 06-07-2017 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS24255 86798111da1cfa28d8b1c3b1aeb41424 105 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 1 99 20.319 T 06-07-2017 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS24255 86798111da1cfa28d8b1c3b1aeb41424 105 Pfam PF00467 KOW motif 5 36 5.2E-11 T 06-07-2017 IPR005824 KOW BWK49_RS03790 ec443e9610048d0095fb8bfb47394539 451 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 388 397 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 BWK49_RS03790 ec443e9610048d0095fb8bfb47394539 451 PRINTS PR00465 E-class P450 group IV signature 248 274 2.0E-33 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS03790 ec443e9610048d0095fb8bfb47394539 451 PRINTS PR00465 E-class P450 group IV signature 305 321 2.0E-33 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS03790 ec443e9610048d0095fb8bfb47394539 451 PRINTS PR00465 E-class P450 group IV signature 379 395 2.0E-33 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS03790 ec443e9610048d0095fb8bfb47394539 451 PRINTS PR00465 E-class P450 group IV signature 338 352 2.0E-33 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS03790 ec443e9610048d0095fb8bfb47394539 451 PRINTS PR00465 E-class P450 group IV signature 29 52 2.0E-33 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS03790 ec443e9610048d0095fb8bfb47394539 451 PRINTS PR00465 E-class P450 group IV signature 354 372 2.0E-33 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS03790 ec443e9610048d0095fb8bfb47394539 451 PRINTS PR00465 E-class P450 group IV signature 395 413 2.0E-33 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS03790 ec443e9610048d0095fb8bfb47394539 451 Gene3D G3DSA:1.10.630.10 18 450 3.5E-97 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS03790 ec443e9610048d0095fb8bfb47394539 451 PRINTS PR00385 P450 superfamily signature 310 321 3.7E-11 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS03790 ec443e9610048d0095fb8bfb47394539 451 PRINTS PR00385 P450 superfamily signature 386 395 3.7E-11 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS03790 ec443e9610048d0095fb8bfb47394539 451 PRINTS PR00385 P450 superfamily signature 257 274 3.7E-11 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS03790 ec443e9610048d0095fb8bfb47394539 451 PRINTS PR00385 P450 superfamily signature 395 406 3.7E-11 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS03790 ec443e9610048d0095fb8bfb47394539 451 SUPERFAMILY SSF48264 17 449 1.44E-97 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS03790 ec443e9610048d0095fb8bfb47394539 451 Pfam PF00067 Cytochrome P450 19 444 1.4E-66 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS18835 35f386bfc647273dc40e46e7421d6f36 353 Gene3D G3DSA:3.40.50.300 30 184 2.7E-29 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS18835 35f386bfc647273dc40e46e7421d6f36 353 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 20 245 4.1E-106 T 06-07-2017 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 BWK49_RS18835 35f386bfc647273dc40e46e7421d6f36 353 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 353 160.558 T 06-07-2017 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 BWK49_RS18835 35f386bfc647273dc40e46e7421d6f36 353 Gene3D G3DSA:1.10.8.60 193 265 3.8E-32 T 06-07-2017 BWK49_RS18835 35f386bfc647273dc40e46e7421d6f36 353 Gene3D G3DSA:1.10.10.10 267 337 7.5E-31 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS18835 35f386bfc647273dc40e46e7421d6f36 353 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 263 334 2.0E-23 T 06-07-2017 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 BWK49_RS18835 35f386bfc647273dc40e46e7421d6f36 353 SMART SM00382 61 192 4.2E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS18835 35f386bfc647273dc40e46e7421d6f36 353 SUPERFAMILY SSF46785 266 340 6.8E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS18835 35f386bfc647273dc40e46e7421d6f36 353 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 34 337 1.5E-140 T 06-07-2017 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 BWK49_RS18835 35f386bfc647273dc40e46e7421d6f36 353 SUPERFAMILY SSF52540 30 260 2.76E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS18835 35f386bfc647273dc40e46e7421d6f36 353 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 263 336 1.4E-29 T 06-07-2017 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 BWK49_RS05515 05ad3f2955ce065c7c7b4feebb1784dc 468 SUPERFAMILY SSF46689 33 140 9.5E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS05515 05ad3f2955ce065c7c7b4feebb1784dc 468 Pfam PF00665 Integrase core domain 159 272 1.4E-25 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 BWK49_RS05515 05ad3f2955ce065c7c7b4feebb1784dc 468 Pfam PF13518 Helix-turn-helix domain 38 86 7.8E-10 T 06-07-2017 BWK49_RS05515 05ad3f2955ce065c7c7b4feebb1784dc 468 Pfam PF09299 Mu transposase, C-terminal 341 388 1.0E-9 T 06-07-2017 IPR015378 Transposase-like, Mu, C-terminal BWK49_RS05515 05ad3f2955ce065c7c7b4feebb1784dc 468 SUPERFAMILY SSF53098 155 321 8.47E-29 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS05515 05ad3f2955ce065c7c7b4feebb1784dc 468 Gene3D G3DSA:3.30.420.10 155 319 7.2E-39 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS27560 e9225d61400208fbffab10d0f754632f 191 SUPERFAMILY SSF46689 7 65 5.49E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS27560 e9225d61400208fbffab10d0f754632f 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 1.4E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS27560 e9225d61400208fbffab10d0f754632f 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 1.4E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS27560 e9225d61400208fbffab10d0f754632f 191 SUPERFAMILY SSF48498 74 189 3.02E-21 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS27560 e9225d61400208fbffab10d0f754632f 191 Gene3D G3DSA:1.10.10.60 7 54 3.9E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS27560 e9225d61400208fbffab10d0f754632f 191 Gene3D G3DSA:1.10.357.10 56 191 1.6E-23 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS27560 e9225d61400208fbffab10d0f754632f 191 Pfam PF16859 Bacterial transcriptional repressor C-terminal 73 183 2.0E-21 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS27560 e9225d61400208fbffab10d0f754632f 191 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 63 6.0E-14 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS01060 9b52efc1546cef2c5e1c269acbedd7b3 419 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 415 38.198 T 06-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 BWK49_RS01060 9b52efc1546cef2c5e1c269acbedd7b3 419 PRINTS PR00981 Seryl-tRNA synthetase signature 259 271 2.2E-30 T 06-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 BWK49_RS01060 9b52efc1546cef2c5e1c269acbedd7b3 419 PRINTS PR00981 Seryl-tRNA synthetase signature 311 324 2.2E-30 T 06-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 BWK49_RS01060 9b52efc1546cef2c5e1c269acbedd7b3 419 PRINTS PR00981 Seryl-tRNA synthetase signature 328 344 2.2E-30 T 06-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 BWK49_RS01060 9b52efc1546cef2c5e1c269acbedd7b3 419 PRINTS PR00981 Seryl-tRNA synthetase signature 271 284 2.2E-30 T 06-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 BWK49_RS01060 9b52efc1546cef2c5e1c269acbedd7b3 419 PRINTS PR00981 Seryl-tRNA synthetase signature 346 362 2.2E-30 T 06-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 BWK49_RS01060 9b52efc1546cef2c5e1c269acbedd7b3 419 Gene3D G3DSA:1.10.287.40 2 102 1.2E-27 T 06-07-2017 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 BWK49_RS01060 9b52efc1546cef2c5e1c269acbedd7b3 419 TIGRFAM TIGR00414 serS: serine--tRNA ligase 2 409 2.6E-123 T 06-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 BWK49_RS01060 9b52efc1546cef2c5e1c269acbedd7b3 419 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 106 1.4E-23 T 06-07-2017 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 BWK49_RS01060 9b52efc1546cef2c5e1c269acbedd7b3 419 SUPERFAMILY SSF46589 2 111 1.46E-21 T 06-07-2017 IPR010978 tRNA-binding arm GO:0000166 BWK49_RS01060 9b52efc1546cef2c5e1c269acbedd7b3 419 SUPERFAMILY SSF55681 118 417 4.7E-85 T 06-07-2017 BWK49_RS01060 9b52efc1546cef2c5e1c269acbedd7b3 419 PIRSF PIRSF001529 1 417 6.0E-130 T 06-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 BWK49_RS01060 9b52efc1546cef2c5e1c269acbedd7b3 419 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 217 393 6.5E-27 T 06-07-2017 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 BWK49_RS01060 9b52efc1546cef2c5e1c269acbedd7b3 419 Gene3D G3DSA:3.30.930.10 104 412 3.0E-116 T 06-07-2017 BWK49_RS14220 5297b4b7228f08431e6cf11568374df7 293 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 9 223 5.1E-48 T 06-07-2017 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 BWK49_RS14220 5297b4b7228f08431e6cf11568374df7 293 PIRSF PIRSF015582 2 292 4.4E-84 T 06-07-2017 IPR011206 Citrate lyase beta subunit-like BWK49_RS14220 5297b4b7228f08431e6cf11568374df7 293 SUPERFAMILY SSF51621 5 233 8.79E-70 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 BWK49_RS14220 5297b4b7228f08431e6cf11568374df7 293 Gene3D G3DSA:3.20.20.60 5 233 1.4E-76 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 BWK49_RS15085 56192aef123e01421461b6033e69116e 249 Gene3D G3DSA:1.10.1660.10 12 89 6.6E-17 T 06-07-2017 BWK49_RS15085 56192aef123e01421461b6033e69116e 249 Pfam PF00376 MerR family regulatory protein 24 54 9.3E-11 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 BWK49_RS15085 56192aef123e01421461b6033e69116e 249 SMART SM00422 12 86 5.8E-21 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 BWK49_RS15085 56192aef123e01421461b6033e69116e 249 SUPERFAMILY SSF46955 27 94 2.52E-12 T 06-07-2017 IPR009061 Putative DNA-binding domain BWK49_RS04055 a97b93d83fa8c617ee07a5eac42be5bb 129 SUPERFAMILY SSF55718 67 115 9.42E-5 T 06-07-2017 IPR003033 SCP2 sterol-binding domain BWK49_RS25930 bcba341c69e636031e334f97a11ea882 249 SMART SM00849 21 228 1.6E-26 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS25930 bcba341c69e636031e334f97a11ea882 249 SUPERFAMILY SSF56281 10 236 1.13E-39 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS25930 bcba341c69e636031e334f97a11ea882 249 Gene3D G3DSA:3.60.15.10 11 234 6.5E-40 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS25930 bcba341c69e636031e334f97a11ea882 249 Pfam PF00753 Metallo-beta-lactamase superfamily 19 228 4.5E-37 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS06735 8a2ff0936c4d53f7821a3c43127f6c85 493 Gene3D G3DSA:3.90.226.10 276 460 4.2E-29 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS06735 8a2ff0936c4d53f7821a3c43127f6c85 493 Gene3D G3DSA:3.90.226.10 4 221 1.7E-44 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS06735 8a2ff0936c4d53f7821a3c43127f6c85 493 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 71 85 4.4E-23 T 06-07-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 BWK49_RS06735 8a2ff0936c4d53f7821a3c43127f6c85 493 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 171 182 4.4E-23 T 06-07-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 BWK49_RS06735 8a2ff0936c4d53f7821a3c43127f6c85 493 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 193 202 4.4E-23 T 06-07-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 BWK49_RS06735 8a2ff0936c4d53f7821a3c43127f6c85 493 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 105 123 4.4E-23 T 06-07-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 BWK49_RS06735 8a2ff0936c4d53f7821a3c43127f6c85 493 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 142 159 4.4E-23 T 06-07-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 BWK49_RS06735 8a2ff0936c4d53f7821a3c43127f6c85 493 Pfam PF01039 Carboxyl transferase domain 37 478 1.3E-70 T 06-07-2017 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 BWK49_RS06735 8a2ff0936c4d53f7821a3c43127f6c85 493 SUPERFAMILY SSF52096 5 221 5.53E-53 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS06735 8a2ff0936c4d53f7821a3c43127f6c85 493 SUPERFAMILY SSF52096 239 491 4.07E-43 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS19295 2142fde252a42efb2a492758ea976096 458 Pfam PF01593 Flavin containing amine oxidoreductase 13 446 1.1E-27 T 06-07-2017 IPR002937 Amine oxidase GO:0016491|GO:0055114 BWK49_RS19295 2142fde252a42efb2a492758ea976096 458 SUPERFAMILY SSF54373 297 399 6.08E-23 T 06-07-2017 BWK49_RS19295 2142fde252a42efb2a492758ea976096 458 SUPERFAMILY SSF51905 7 311 4.53E-34 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS19295 2142fde252a42efb2a492758ea976096 458 SUPERFAMILY SSF51905 413 445 4.53E-34 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS19295 2142fde252a42efb2a492758ea976096 458 Gene3D G3DSA:1.10.3110.10 118 194 7.5E-12 T 06-07-2017 BWK49_RS19295 2142fde252a42efb2a492758ea976096 458 Gene3D G3DSA:3.40.50.720 3 47 2.1E-5 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS19295 2142fde252a42efb2a492758ea976096 458 TIGRFAM TIGR00562 proto_IX_ox: protoporphyrinogen oxidase 6 446 3.8E-35 T 06-07-2017 IPR004572 Protoporphyrinogen oxidase GO:0004729|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.4|MetaCyc: PWY-7159|Reactome: R-HSA-189451 BWK49_RS19295 2142fde252a42efb2a492758ea976096 458 Gene3D G3DSA:3.90.660.20 240 399 5.4E-20 T 06-07-2017 IPR027418 Protoporphyrinogen oxidase, C-terminal domain KEGG: 00860+1.3.3.4|MetaCyc: PWY-7159|Reactome: R-HSA-189451 BWK49_RS13880 fed2685e24b19c774bc2ff20710c466f 415 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 129 220 2.4E-18 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 BWK49_RS13880 fed2685e24b19c774bc2ff20710c466f 415 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 4 122 2.8E-15 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS13880 fed2685e24b19c774bc2ff20710c466f 415 Gene3D G3DSA:1.10.540.10 3 123 1.4E-18 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS13880 fed2685e24b19c774bc2ff20710c466f 415 SUPERFAMILY SSF47203 232 391 1.05E-7 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS13880 fed2685e24b19c774bc2ff20710c466f 415 Gene3D G3DSA:1.20.140.10 223 393 5.5E-13 T 06-07-2017 BWK49_RS13880 fed2685e24b19c774bc2ff20710c466f 415 SUPERFAMILY SSF56645 3 244 6.81E-54 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS13880 fed2685e24b19c774bc2ff20710c466f 415 Gene3D G3DSA:2.40.110.10 128 222 6.1E-27 T 06-07-2017 BWK49_RS13880 fed2685e24b19c774bc2ff20710c466f 415 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 232 387 1.5E-6 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS03295 6cd6a145030f7a472b1610e7b323ff0a 388 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 231 244 - T 06-07-2017 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 BWK49_RS03295 6cd6a145030f7a472b1610e7b323ff0a 388 Gene3D G3DSA:3.90.1150.10 254 385 5.8E-33 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 BWK49_RS03295 6cd6a145030f7a472b1610e7b323ff0a 388 Gene3D G3DSA:3.40.640.10 46 253 1.6E-62 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 BWK49_RS03295 6cd6a145030f7a472b1610e7b323ff0a 388 Pfam PF00155 Aminotransferase class I and II 32 381 4.8E-59 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 BWK49_RS03295 6cd6a145030f7a472b1610e7b323ff0a 388 SUPERFAMILY SSF53383 9 385 8.16E-100 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase BWK49_RS19850 bbdc545ff18b31a91cc90a32c816c4e6 400 Pfam PF02803 Thiolase, C-terminal domain 274 376 5.1E-10 T 06-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 BWK49_RS19850 bbdc545ff18b31a91cc90a32c816c4e6 400 SUPERFAMILY SSF53901 9 240 2.72E-49 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS19850 bbdc545ff18b31a91cc90a32c816c4e6 400 Gene3D G3DSA:3.40.47.10 26 123 2.0E-26 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS19850 bbdc545ff18b31a91cc90a32c816c4e6 400 Gene3D G3DSA:3.40.47.10 211 232 2.0E-26 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS19850 bbdc545ff18b31a91cc90a32c816c4e6 400 Pfam PF00108 Thiolase, N-terminal domain 9 233 3.7E-18 T 06-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 BWK49_RS19850 bbdc545ff18b31a91cc90a32c816c4e6 400 SUPERFAMILY SSF53901 263 386 2.18E-30 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS19850 bbdc545ff18b31a91cc90a32c816c4e6 400 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 84 102 - T 06-07-2017 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 BWK49_RS19850 bbdc545ff18b31a91cc90a32c816c4e6 400 PIRSF PIRSF000429 3 396 9.8E-67 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 BWK49_RS19850 bbdc545ff18b31a91cc90a32c816c4e6 400 ProSitePatterns PS00737 Thiolases signature 2. 337 353 - T 06-07-2017 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 BWK49_RS19850 bbdc545ff18b31a91cc90a32c816c4e6 400 Gene3D G3DSA:3.40.47.10 146 192 6.8E-25 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS19850 bbdc545ff18b31a91cc90a32c816c4e6 400 Gene3D G3DSA:3.40.47.10 257 393 6.8E-25 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS09175 c4e8cb2844c726b38be839bb32621999 578 Pfam PF00664 ABC transporter transmembrane region 18 280 2.3E-6 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 BWK49_RS09175 c4e8cb2844c726b38be839bb32621999 578 Gene3D G3DSA:3.40.50.300 330 558 1.2E-72 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS09175 c4e8cb2844c726b38be839bb32621999 578 Gene3D G3DSA:1.20.1560.10 13 314 2.0E-22 T 06-07-2017 BWK49_RS09175 c4e8cb2844c726b38be839bb32621999 578 SMART SM00382 357 549 7.7E-18 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS09175 c4e8cb2844c726b38be839bb32621999 578 SUPERFAMILY SSF90123 13 307 1.44E-30 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 BWK49_RS09175 c4e8cb2844c726b38be839bb32621999 578 SUPERFAMILY SSF52540 327 567 1.03E-79 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS09175 c4e8cb2844c726b38be839bb32621999 578 ProSitePatterns PS00211 ABC transporters family signature. 469 483 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 BWK49_RS09175 c4e8cb2844c726b38be839bb32621999 578 Pfam PF00005 ABC transporter 348 497 5.0E-34 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 BWK49_RS10075 d9218b96f841f5366ef3c04939cbf2b6 224 SUPERFAMILY SSF53254 1 197 4.53E-51 T 06-07-2017 IPR029033 Histidine phosphatase superfamily BWK49_RS10075 d9218b96f841f5366ef3c04939cbf2b6 224 Gene3D G3DSA:3.40.50.1240 2 218 6.4E-54 T 06-07-2017 IPR029033 Histidine phosphatase superfamily BWK49_RS10075 d9218b96f841f5366ef3c04939cbf2b6 224 SMART SM00855 5 166 1.6E-20 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 BWK49_RS10075 d9218b96f841f5366ef3c04939cbf2b6 224 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 8 17 - T 06-07-2017 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 BWK49_RS10075 d9218b96f841f5366ef3c04939cbf2b6 224 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 6 214 1.5E-49 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 BWK49_RS25505 d91d3f31a4f16a379dea8776b8f951fd 465 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 346 453 2.0E-35 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 BWK49_RS25505 d91d3f31a4f16a379dea8776b8f951fd 465 Gene3D G3DSA:3.30.390.30 332 463 1.3E-43 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 BWK49_RS25505 d91d3f31a4f16a379dea8776b8f951fd 465 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 325 8.6E-64 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS25505 d91d3f31a4f16a379dea8776b8f951fd 465 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 39 49 - T 06-07-2017 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 BWK49_RS25505 d91d3f31a4f16a379dea8776b8f951fd 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 139 148 2.4E-63 T 06-07-2017 BWK49_RS25505 d91d3f31a4f16a379dea8776b8f951fd 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 2.4E-63 T 06-07-2017 BWK49_RS25505 d91d3f31a4f16a379dea8776b8f951fd 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 174 199 2.4E-63 T 06-07-2017 BWK49_RS25505 d91d3f31a4f16a379dea8776b8f951fd 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 262 276 2.4E-63 T 06-07-2017 BWK49_RS25505 d91d3f31a4f16a379dea8776b8f951fd 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 429 449 2.4E-63 T 06-07-2017 BWK49_RS25505 d91d3f31a4f16a379dea8776b8f951fd 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 305 312 2.4E-63 T 06-07-2017 BWK49_RS25505 d91d3f31a4f16a379dea8776b8f951fd 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 407 422 2.4E-63 T 06-07-2017 BWK49_RS25505 d91d3f31a4f16a379dea8776b8f951fd 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 2.4E-63 T 06-07-2017 BWK49_RS25505 d91d3f31a4f16a379dea8776b8f951fd 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 342 363 2.4E-63 T 06-07-2017 BWK49_RS25505 d91d3f31a4f16a379dea8776b8f951fd 465 PIRSF PIRSF000350 1 460 1.9E-88 T 06-07-2017 BWK49_RS25505 d91d3f31a4f16a379dea8776b8f951fd 465 Gene3D G3DSA:3.50.50.60 3 142 2.4E-37 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS25505 d91d3f31a4f16a379dea8776b8f951fd 465 SUPERFAMILY SSF51905 3 371 1.55E-59 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS25505 d91d3f31a4f16a379dea8776b8f951fd 465 SUPERFAMILY SSF55424 342 464 1.25E-38 T 06-07-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 BWK49_RS25505 d91d3f31a4f16a379dea8776b8f951fd 465 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 4 464 2.2E-164 T 06-07-2017 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 BWK49_RS25505 d91d3f31a4f16a379dea8776b8f951fd 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 290 312 2.4E-32 T 06-07-2017 BWK49_RS25505 d91d3f31a4f16a379dea8776b8f951fd 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 261 277 2.4E-32 T 06-07-2017 BWK49_RS25505 d91d3f31a4f16a379dea8776b8f951fd 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 2.4E-32 T 06-07-2017 BWK49_RS25505 d91d3f31a4f16a379dea8776b8f951fd 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 174 192 2.4E-32 T 06-07-2017 BWK49_RS25505 d91d3f31a4f16a379dea8776b8f951fd 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 136 154 2.4E-32 T 06-07-2017 BWK49_RS25505 d91d3f31a4f16a379dea8776b8f951fd 465 Gene3D G3DSA:3.50.50.60 143 331 3.4E-50 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS26550 5d7192485a68653173402a0899c94d06 733 Gene3D G3DSA:1.20.140.10 219 346 1.0E-31 T 06-07-2017 BWK49_RS26550 5d7192485a68653173402a0899c94d06 733 SUPERFAMILY SSF56645 1 203 2.62E-22 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS26550 5d7192485a68653173402a0899c94d06 733 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 475 563 3.3E-17 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 BWK49_RS26550 5d7192485a68653173402a0899c94d06 733 Gene3D G3DSA:1.20.140.10 571 732 1.3E-28 T 06-07-2017 BWK49_RS26550 5d7192485a68653173402a0899c94d06 733 Gene3D G3DSA:2.40.110.10 474 570 3.9E-30 T 06-07-2017 BWK49_RS26550 5d7192485a68653173402a0899c94d06 733 Gene3D G3DSA:1.10.540.10 371 473 1.1E-12 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS26550 5d7192485a68653173402a0899c94d06 733 SUPERFAMILY SSF56645 366 592 7.72E-57 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS26550 5d7192485a68653173402a0899c94d06 733 SUPERFAMILY SSF47203 581 729 9.34E-18 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS26550 5d7192485a68653173402a0899c94d06 733 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 581 727 7.6E-17 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS26550 5d7192485a68653173402a0899c94d06 733 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 218 346 1.5E-22 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS26550 5d7192485a68653173402a0899c94d06 733 SUPERFAMILY SSF47203 217 348 1.93E-31 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS26550 5d7192485a68653173402a0899c94d06 733 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 97 1.3E-11 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS26550 5d7192485a68653173402a0899c94d06 733 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 382 471 4.0E-12 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS26550 5d7192485a68653173402a0899c94d06 733 Gene3D G3DSA:1.10.540.10 3 97 1.1E-13 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS27000 7b4f844c26dfa7edd99ee7ed1f297876 437 SUPERFAMILY SSF51556 50 111 1.65E-23 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS27000 7b4f844c26dfa7edd99ee7ed1f297876 437 SUPERFAMILY SSF51556 162 368 1.65E-23 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS27000 7b4f844c26dfa7edd99ee7ed1f297876 437 Gene3D G3DSA:2.30.40.10 340 434 1.0E-6 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 BWK49_RS27000 7b4f844c26dfa7edd99ee7ed1f297876 437 Pfam PF07969 Amidohydrolase family 43 434 3.1E-28 T 06-07-2017 IPR013108 Amidohydrolase 3 BWK49_RS27000 7b4f844c26dfa7edd99ee7ed1f297876 437 Gene3D G3DSA:2.30.40.10 1 91 2.7E-7 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 BWK49_RS27000 7b4f844c26dfa7edd99ee7ed1f297876 437 Gene3D G3DSA:3.20.20.140 228 339 8.8E-12 T 06-07-2017 BWK49_RS07950 9926c2e752841cc9e6a698f3feef50eb 277 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 8 249 9.7E-59 T 06-07-2017 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 BWK49_RS07950 9926c2e752841cc9e6a698f3feef50eb 277 Gene3D G3DSA:3.40.50.150 58 190 1.4E-13 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS07950 9926c2e752841cc9e6a698f3feef50eb 277 Pfam PF04072 Leucine carboxyl methyltransferase 10 183 2.2E-44 T 06-07-2017 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 BWK49_RS07950 9926c2e752841cc9e6a698f3feef50eb 277 SUPERFAMILY SSF53335 6 260 1.41E-51 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS21940 8890de3e3feca3c1f7ad6ed1470b1c08 364 Pfam PF04209 homogentisate 1,2-dioxygenase 103 287 4.5E-11 T 06-07-2017 IPR005708 Homogentisate 1,2-dioxygenase GO:0004411|GO:0006559|GO:0006570|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5|Reactome: R-HSA-71182 BWK49_RS21940 8890de3e3feca3c1f7ad6ed1470b1c08 364 Gene3D G3DSA:2.60.120.10 212 337 7.1E-12 T 06-07-2017 IPR014710 RmlC-like jelly roll fold BWK49_RS21940 8890de3e3feca3c1f7ad6ed1470b1c08 364 Gene3D G3DSA:2.60.120.10 83 159 1.7E-10 T 06-07-2017 IPR014710 RmlC-like jelly roll fold BWK49_RS21940 8890de3e3feca3c1f7ad6ed1470b1c08 364 SUPERFAMILY SSF51182 52 354 1.21E-68 T 06-07-2017 IPR011051 RmlC-like cupin domain BWK49_RS22600 db8c18ab5779009e4f5030c725b18f66 340 Pfam PF13180 PDZ domain 134 194 1.7E-11 T 06-07-2017 IPR001478 PDZ domain GO:0005515 BWK49_RS22600 db8c18ab5779009e4f5030c725b18f66 340 Gene3D G3DSA:2.30.42.10 134 206 7.8E-13 T 06-07-2017 IPR001478 PDZ domain GO:0005515 BWK49_RS22600 db8c18ab5779009e4f5030c725b18f66 340 SUPERFAMILY SSF50156 133 237 2.1E-16 T 06-07-2017 IPR001478 PDZ domain GO:0005515 BWK49_RS22600 db8c18ab5779009e4f5030c725b18f66 340 Gene3D G3DSA:3.30.230.10 233 328 5.3E-21 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup BWK49_RS22600 db8c18ab5779009e4f5030c725b18f66 340 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 236 305 2.0E-9 T 06-07-2017 IPR008269 Peptidase S16, Lon C-terminal GO:0004176|GO:0004252|GO:0006508 BWK49_RS22600 db8c18ab5779009e4f5030c725b18f66 340 SUPERFAMILY SSF54211 232 328 1.86E-19 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold BWK49_RS17925 98fd262d5e497317e615f734f92e5c10 545 ProSitePatterns PS00211 ABC transporters family signature. 456 470 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 BWK49_RS17925 98fd262d5e497317e615f734f92e5c10 545 SMART SM00382 363 528 5.6E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS17925 98fd262d5e497317e615f734f92e5c10 545 SMART SM00382 28 245 1.1E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS17925 98fd262d5e497317e615f734f92e5c10 545 Pfam PF12848 ABC transporter 245 316 2.1E-7 T 06-07-2017 IPR032781 ABC-transporter extension domain BWK49_RS17925 98fd262d5e497317e615f734f92e5c10 545 SUPERFAMILY SSF52540 19 241 5.22E-36 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS17925 98fd262d5e497317e615f734f92e5c10 545 Pfam PF00005 ABC transporter 356 484 3.3E-21 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 BWK49_RS17925 98fd262d5e497317e615f734f92e5c10 545 Pfam PF00005 ABC transporter 23 200 1.0E-18 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 BWK49_RS17925 98fd262d5e497317e615f734f92e5c10 545 Gene3D G3DSA:3.40.50.300 138 289 4.7E-40 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS17925 98fd262d5e497317e615f734f92e5c10 545 Gene3D G3DSA:3.40.50.300 20 104 4.7E-40 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS17925 98fd262d5e497317e615f734f92e5c10 545 Gene3D G3DSA:3.40.50.300 341 530 8.8E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS17925 98fd262d5e497317e615f734f92e5c10 545 ProSitePatterns PS00211 ABC transporters family signature. 162 176 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 BWK49_RS17925 98fd262d5e497317e615f734f92e5c10 545 SUPERFAMILY SSF52540 343 529 7.7E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS09540 df3165e7fc593def269e9ea634e314ad 64 Gene3D G3DSA:3.30.70.20 1 63 5.2E-16 T 06-07-2017 BWK49_RS09540 df3165e7fc593def269e9ea634e314ad 64 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 5 59 1.4E-11 T 06-07-2017 BWK49_RS09540 df3165e7fc593def269e9ea634e314ad 64 PRINTS PR00352 3Fe-4S ferredoxin signature 16 26 3.4E-5 T 06-07-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 BWK49_RS09540 df3165e7fc593def269e9ea634e314ad 64 PRINTS PR00352 3Fe-4S ferredoxin signature 5 16 3.4E-5 T 06-07-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 BWK49_RS09540 df3165e7fc593def269e9ea634e314ad 64 PRINTS PR00352 3Fe-4S ferredoxin signature 47 59 3.4E-5 T 06-07-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 BWK49_RS09540 df3165e7fc593def269e9ea634e314ad 64 SUPERFAMILY SSF54862 2 63 1.57E-10 T 06-07-2017 BWK49_RS24130 b09156d28c6eb0b8e2757646771a35b6 181 SUPERFAMILY SSF88659 111 174 2.09E-13 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS24130 b09156d28c6eb0b8e2757646771a35b6 181 Pfam PF04545 Sigma-70, region 4 123 171 2.6E-14 T 06-07-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS24130 b09156d28c6eb0b8e2757646771a35b6 181 Gene3D G3DSA:1.10.1740.10 13 90 1.9E-20 T 06-07-2017 BWK49_RS24130 b09156d28c6eb0b8e2757646771a35b6 181 Pfam PF04542 Sigma-70 region 2 22 89 1.0E-16 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS24130 b09156d28c6eb0b8e2757646771a35b6 181 SUPERFAMILY SSF88946 17 108 5.49E-20 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS24130 b09156d28c6eb0b8e2757646771a35b6 181 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 20 172 9.1E-27 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS24130 b09156d28c6eb0b8e2757646771a35b6 181 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 44 76 - T 06-07-2017 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS24130 b09156d28c6eb0b8e2757646771a35b6 181 Gene3D G3DSA:1.10.10.10 115 176 1.0E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS20490 dc808a311ab0394a2c683dc9693d3341 193 Gene3D G3DSA:1.10.260.40 4 35 4.0E-4 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 BWK49_RS07635 8fdf442dc47707b2dda1af4ffb7d399d 379 Gene3D G3DSA:2.130.10.10 48 341 9.2E-48 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 BWK49_RS07635 8fdf442dc47707b2dda1af4ffb7d399d 379 SUPERFAMILY SSF51004 65 336 3.4E-38 T 06-07-2017 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain BWK49_RS07635 8fdf442dc47707b2dda1af4ffb7d399d 379 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 51 90 9.1E-9 T 06-07-2017 IPR011964 YVTN beta-propeller repeat BWK49_RS25770 100704b2aaa832bacb521c23c9303b3e 546 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 79 506 55.72 T 06-07-2017 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 BWK49_RS25770 100704b2aaa832bacb521c23c9303b3e 546 Pfam PF13667 ThiC-associated domain 19 78 2.5E-9 T 06-07-2017 IPR025747 ThiC-associated domain KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 BWK49_RS25770 100704b2aaa832bacb521c23c9303b3e 546 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 80 503 2.1E-208 T 06-07-2017 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 BWK49_RS25770 100704b2aaa832bacb521c23c9303b3e 546 Pfam PF01964 Radical SAM ThiC family 80 500 1.9E-200 T 06-07-2017 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 BWK49_RS12940 e275ed2b69a94d4fbc67e422db565dce 600 SUPERFAMILY SSF56801 338 598 1.96E-114 T 06-07-2017 BWK49_RS12940 e275ed2b69a94d4fbc67e422db565dce 600 SUPERFAMILY SSF56801 26 290 1.96E-114 T 06-07-2017 BWK49_RS12940 e275ed2b69a94d4fbc67e422db565dce 600 Gene3D G3DSA:3.30.300.30 465 587 2.1E-6 T 06-07-2017 BWK49_RS12940 e275ed2b69a94d4fbc67e422db565dce 600 ProSitePatterns PS00455 Putative AMP-binding domain signature. 186 197 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS12940 e275ed2b69a94d4fbc67e422db565dce 600 Gene3D G3DSA:3.40.50.980 193 285 3.6E-26 T 06-07-2017 BWK49_RS12940 e275ed2b69a94d4fbc67e422db565dce 600 Gene3D G3DSA:3.40.50.980 335 395 3.6E-26 T 06-07-2017 BWK49_RS12940 e275ed2b69a94d4fbc67e422db565dce 600 Gene3D G3DSA:3.40.50.980 24 192 5.8E-31 T 06-07-2017 BWK49_RS12940 e275ed2b69a94d4fbc67e422db565dce 600 Gene3D G3DSA:2.30.38.10 405 461 6.7E-21 T 06-07-2017 BWK49_RS12940 e275ed2b69a94d4fbc67e422db565dce 600 Pfam PF00501 AMP-binding enzyme 32 467 6.2E-94 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS23790 092e4e1cd0cbec4cd7535db4b770bbed 100 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 14 99 19.172 T 06-07-2017 IPR003482 Transcription factor WhiB BWK49_RS23790 092e4e1cd0cbec4cd7535db4b770bbed 100 Pfam PF02467 Transcription factor WhiB 17 85 1.7E-24 T 06-07-2017 IPR003482 Transcription factor WhiB BWK49_RS27480 e5aef5c268b3115d515481621a5d7df8 313 Pfam PF04072 Leucine carboxyl methyltransferase 29 211 6.3E-61 T 06-07-2017 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 BWK49_RS27480 e5aef5c268b3115d515481621a5d7df8 313 Gene3D G3DSA:3.40.50.150 34 229 4.8E-19 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS27480 e5aef5c268b3115d515481621a5d7df8 313 SUPERFAMILY SSF53335 25 306 1.66E-75 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS27480 e5aef5c268b3115d515481621a5d7df8 313 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 27 288 1.5E-86 T 06-07-2017 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 BWK49_RS24350 553647f494f446396eca35c6eb8119c8 472 Gene3D G3DSA:3.90.550.10 86 287 2.0E-35 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases BWK49_RS24350 553647f494f446396eca35c6eb8119c8 472 TIGRFAM TIGR03965 mycofact_glyco: mycofactocin system glycosyltransferase 14 471 2.2E-181 T 06-07-2017 IPR023981 Putative mycofactocin biosynthesis glycosyltransferase BWK49_RS24350 553647f494f446396eca35c6eb8119c8 472 Pfam PF00535 Glycosyl transferase family 2 87 245 4.2E-23 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 BWK49_RS24350 553647f494f446396eca35c6eb8119c8 472 SUPERFAMILY SSF53448 83 299 3.45E-43 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases BWK49_RS00790 5eb629efb442fb21a326c731a28ee241 302 Pfam PF04072 Leucine carboxyl methyltransferase 19 194 8.5E-54 T 06-07-2017 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 BWK49_RS00790 5eb629efb442fb21a326c731a28ee241 302 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 18 272 8.4E-74 T 06-07-2017 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 BWK49_RS00790 5eb629efb442fb21a326c731a28ee241 302 SUPERFAMILY SSF53335 15 283 8.31E-66 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS00790 5eb629efb442fb21a326c731a28ee241 302 Gene3D G3DSA:3.40.50.150 57 204 7.0E-16 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS00515 07399efbbff9f7b183499af87698350a 209 Gene3D G3DSA:1.10.357.10 3 139 1.7E-21 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS00515 07399efbbff9f7b183499af87698350a 209 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 64 2.5E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS00515 07399efbbff9f7b183499af87698350a 209 SUPERFAMILY SSF46689 6 82 2.92E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS10850 9eeb7463ad17ba49e06a31ccf769c6cf 176 Pfam PF13577 SnoaL-like domain 2 120 2.7E-19 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain BWK49_RS10850 9eeb7463ad17ba49e06a31ccf769c6cf 176 SUPERFAMILY SSF54427 1 141 5.8E-32 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS10850 9eeb7463ad17ba49e06a31ccf769c6cf 176 Gene3D G3DSA:3.10.450.50 3 129 1.9E-29 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS17465 0dba83ef9f33846c109ae64db230cebc 578 Pfam PF11941 Domain of unknown function (DUF3459) 488 570 9.2E-19 T 06-07-2017 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) BWK49_RS17465 0dba83ef9f33846c109ae64db230cebc 578 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 2 50 7.2E-5 T 06-07-2017 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 BWK49_RS17465 0dba83ef9f33846c109ae64db230cebc 578 SUPERFAMILY SSF81296 3 77 2.4E-16 T 06-07-2017 IPR014756 Immunoglobulin E-set BWK49_RS17465 0dba83ef9f33846c109ae64db230cebc 578 PIRSF PIRSF006337 1 574 2.5E-232 T 06-07-2017 IPR012768 Malto-oligosyltrehalose trehalohydrolase GO:0004553|GO:0005992 KEGG: 00520+3.2.1.14|MetaCyc: PWY-2661|MetaCyc: PWY-6902 BWK49_RS17465 0dba83ef9f33846c109ae64db230cebc 578 Gene3D G3DSA:3.20.20.80 92 425 7.4E-73 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 BWK49_RS17465 0dba83ef9f33846c109ae64db230cebc 578 Gene3D G3DSA:3.20.20.80 468 502 7.4E-73 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 BWK49_RS17465 0dba83ef9f33846c109ae64db230cebc 578 Pfam PF00128 Alpha amylase, catalytic domain 109 204 7.7E-15 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 BWK49_RS17465 0dba83ef9f33846c109ae64db230cebc 578 SMART SM00642 99 496 1.8E-7 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 BWK49_RS17465 0dba83ef9f33846c109ae64db230cebc 578 TIGRFAM TIGR02402 trehalose_TreZ: malto-oligosyltrehalose trehalohydrolase 3 542 5.1E-234 T 06-07-2017 IPR012768 Malto-oligosyltrehalose trehalohydrolase GO:0004553|GO:0005992 KEGG: 00520+3.2.1.14|MetaCyc: PWY-2661|MetaCyc: PWY-6902 BWK49_RS17465 0dba83ef9f33846c109ae64db230cebc 578 SUPERFAMILY SSF51445 75 502 8.22E-100 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily BWK49_RS17465 0dba83ef9f33846c109ae64db230cebc 578 Gene3D G3DSA:2.60.40.10 2 77 4.7E-25 T 06-07-2017 IPR013783 Immunoglobulin-like fold BWK49_RS00060 043226f1d722ec8a11e17839f1de74e9 343 Pfam PF01909 Nucleotidyltransferase domain 45 86 7.5E-5 T 06-07-2017 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 BWK49_RS00060 043226f1d722ec8a11e17839f1de74e9 343 Gene3D G3DSA:3.30.460.10 29 95 3.1E-7 T 06-07-2017 BWK49_RS00060 043226f1d722ec8a11e17839f1de74e9 343 SUPERFAMILY SSF81301 29 80 3.52E-6 T 06-07-2017 BWK49_RS13535 99a647c4e454a9f44757eeb30f26680f 251 SUPERFAMILY SSF52540 21 233 6.86E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS13535 99a647c4e454a9f44757eeb30f26680f 251 Gene3D G3DSA:3.40.50.300 20 232 2.5E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS13535 99a647c4e454a9f44757eeb30f26680f 251 Pfam PF00005 ABC transporter 34 165 2.5E-26 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 BWK49_RS13535 99a647c4e454a9f44757eeb30f26680f 251 SMART SM00382 43 215 7.4E-17 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS13535 99a647c4e454a9f44757eeb30f26680f 251 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 BWK49_RS02085 1cbe2e5429e2cd34583ed0a00086dce7 314 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 17 291 4.4E-89 T 06-07-2017 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 BWK49_RS02085 1cbe2e5429e2cd34583ed0a00086dce7 314 Pfam PF04072 Leucine carboxyl methyltransferase 19 204 1.8E-62 T 06-07-2017 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 BWK49_RS02085 1cbe2e5429e2cd34583ed0a00086dce7 314 SUPERFAMILY SSF53335 15 309 2.57E-73 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS02085 1cbe2e5429e2cd34583ed0a00086dce7 314 Gene3D G3DSA:3.40.50.150 16 214 1.6E-16 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS26625 1ff73ad1bee3b51f5b9fd3e8ec0341bb 252 Pfam PF01903 CbiX 126 216 2.0E-4 T 06-07-2017 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 BWK49_RS26625 1ff73ad1bee3b51f5b9fd3e8ec0341bb 252 Pfam PF01903 CbiX 8 105 1.2E-15 T 06-07-2017 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 BWK49_RS26625 1ff73ad1bee3b51f5b9fd3e8ec0341bb 252 SUPERFAMILY SSF53800 2 223 2.88E-26 T 06-07-2017 BWK49_RS26625 1ff73ad1bee3b51f5b9fd3e8ec0341bb 252 Gene3D G3DSA:3.40.50.1400 2 116 8.6E-24 T 06-07-2017 BWK49_RS26625 1ff73ad1bee3b51f5b9fd3e8ec0341bb 252 Gene3D G3DSA:3.40.50.1400 119 223 7.4E-19 T 06-07-2017 BWK49_RS09555 5e6ca95d0d5452aaed1ba79ab53ec972 521 Pfam PF00501 AMP-binding enzyme 19 409 1.6E-73 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS09555 5e6ca95d0d5452aaed1ba79ab53ec972 521 ProSitePatterns PS00455 Putative AMP-binding domain signature. 168 179 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS09555 5e6ca95d0d5452aaed1ba79ab53ec972 521 SUPERFAMILY SSF56801 12 506 8.37E-118 T 06-07-2017 BWK49_RS09555 5e6ca95d0d5452aaed1ba79ab53ec972 521 Gene3D G3DSA:2.30.38.10 330 403 4.6E-14 T 06-07-2017 BWK49_RS09555 5e6ca95d0d5452aaed1ba79ab53ec972 521 Pfam PF13193 AMP-binding enzyme C-terminal domain 419 493 4.4E-15 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS09555 5e6ca95d0d5452aaed1ba79ab53ec972 521 Gene3D G3DSA:3.40.50.980 174 322 2.6E-25 T 06-07-2017 BWK49_RS09555 5e6ca95d0d5452aaed1ba79ab53ec972 521 Gene3D G3DSA:3.40.50.980 13 173 2.8E-32 T 06-07-2017 BWK49_RS09555 5e6ca95d0d5452aaed1ba79ab53ec972 521 Gene3D G3DSA:3.30.300.30 405 502 9.1E-23 T 06-07-2017 BWK49_RS24960 cf8ac8aca1b4727f257cf5164a63ab64 354 Pfam PF01636 Phosphotransferase enzyme family 38 264 1.6E-26 T 06-07-2017 IPR002575 Aminoglycoside phosphotransferase BWK49_RS24960 cf8ac8aca1b4727f257cf5164a63ab64 354 SUPERFAMILY SSF56112 14 319 1.4E-34 T 06-07-2017 IPR011009 Protein kinase-like domain BWK49_RS24960 cf8ac8aca1b4727f257cf5164a63ab64 354 Gene3D G3DSA:3.90.1200.10 143 306 2.3E-18 T 06-07-2017 BWK49_RS23300 c47627268eb288ee675dcb7c391efa94 268 Pfam PF12706 Beta-lactamase superfamily domain 44 231 5.6E-18 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS23300 c47627268eb288ee675dcb7c391efa94 268 Gene3D G3DSA:3.60.15.10 3 268 3.9E-44 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS23300 c47627268eb288ee675dcb7c391efa94 268 SUPERFAMILY SSF56281 4 259 2.1E-21 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS15765 cab72ecf4838e6a4d2628d385b9993b9 499 SUPERFAMILY SSF51905 441 498 2.47E-43 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS15765 cab72ecf4838e6a4d2628d385b9993b9 499 SUPERFAMILY SSF51905 20 169 2.47E-43 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS15765 cab72ecf4838e6a4d2628d385b9993b9 499 SUPERFAMILY SSF51905 199 314 2.47E-43 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS15765 cab72ecf4838e6a4d2628d385b9993b9 499 Pfam PF00890 FAD binding domain 34 476 1.9E-45 T 06-07-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 BWK49_RS15765 cab72ecf4838e6a4d2628d385b9993b9 499 Gene3D G3DSA:3.90.700.10 313 423 3.0E-17 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 BWK49_RS15765 cab72ecf4838e6a4d2628d385b9993b9 499 Gene3D G3DSA:3.50.50.60 23 297 1.1E-67 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS15765 cab72ecf4838e6a4d2628d385b9993b9 499 Gene3D G3DSA:3.50.50.60 438 498 1.1E-67 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS15765 cab72ecf4838e6a4d2628d385b9993b9 499 SUPERFAMILY SSF56425 313 424 4.88E-20 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 BWK49_RS02465 ed306680cb0c1b942858be2ea2dcad00 611 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 2 360 9.4E-113 T 06-07-2017 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 BWK49_RS02465 ed306680cb0c1b942858be2ea2dcad00 611 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 235 366 4.0E-15 T 06-07-2017 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 BWK49_RS02465 ed306680cb0c1b942858be2ea2dcad00 611 SUPERFAMILY SSF52540 31 220 1.52E-51 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS02465 ed306680cb0c1b942858be2ea2dcad00 611 SUPERFAMILY SSF48019 245 361 4.93E-23 T 06-07-2017 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 BWK49_RS02465 ed306680cb0c1b942858be2ea2dcad00 611 Gene3D G3DSA:1.10.8.60 165 242 2.1E-19 T 06-07-2017 BWK49_RS02465 ed306680cb0c1b942858be2ea2dcad00 611 SMART SM00382 34 177 4.3E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS02465 ed306680cb0c1b942858be2ea2dcad00 611 Gene3D G3DSA:1.20.272.10 243 361 2.3E-16 T 06-07-2017 BWK49_RS02465 ed306680cb0c1b942858be2ea2dcad00 611 Gene3D G3DSA:3.40.50.300 12 164 1.3E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS02465 ed306680cb0c1b942858be2ea2dcad00 611 Pfam PF13177 DNA polymerase III, delta subunit 17 175 3.1E-38 T 06-07-2017 BWK49_RS21080 9e79aa10d818fe842021ee9156ba2356 318 Gene3D G3DSA:3.40.50.620 1 181 2.2E-41 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold BWK49_RS21080 9e79aa10d818fe842021ee9156ba2356 318 PIRSF PIRSF000089 1 318 4.8E-106 T 06-07-2017 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 BWK49_RS21080 9e79aa10d818fe842021ee9156ba2356 318 SMART SM00893 4 193 4.5E-30 T 06-07-2017 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 BWK49_RS21080 9e79aa10d818fe842021ee9156ba2356 318 Pfam PF01012 Electron transfer flavoprotein domain 4 173 4.0E-32 T 06-07-2017 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 BWK49_RS21080 9e79aa10d818fe842021ee9156ba2356 318 SUPERFAMILY SSF52402 4 185 2.44E-40 T 06-07-2017 BWK49_RS21080 9e79aa10d818fe842021ee9156ba2356 318 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 194 276 2.7E-35 T 06-07-2017 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 BWK49_RS21080 9e79aa10d818fe842021ee9156ba2356 318 SUPERFAMILY SSF52467 191 313 3.27E-47 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain BWK49_RS21080 9e79aa10d818fe842021ee9156ba2356 318 Gene3D G3DSA:3.40.50.1220 190 314 4.2E-59 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain BWK49_RS21080 9e79aa10d818fe842021ee9156ba2356 318 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 257 283 - T 06-07-2017 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 BWK49_RS09780 6fbaa67d878d181332c7b76b59cfefc8 415 Gene3D G3DSA:3.40.50.1820 133 391 3.7E-61 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS09780 6fbaa67d878d181332c7b76b59cfefc8 415 SUPERFAMILY SSF53474 123 376 1.68E-49 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS09780 6fbaa67d878d181332c7b76b59cfefc8 415 Pfam PF07859 alpha/beta hydrolase fold 167 373 5.2E-19 T 06-07-2017 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 BWK49_RS26945 f7038daab8ad545c91b45f870e0f8467 195 SUPERFAMILY SSF48498 68 177 9.24E-19 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS26945 f7038daab8ad545c91b45f870e0f8467 195 Gene3D G3DSA:1.10.357.10 2 173 6.8E-23 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS26945 f7038daab8ad545c91b45f870e0f8467 195 SUPERFAMILY SSF46689 2 63 2.41E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS26945 f7038daab8ad545c91b45f870e0f8467 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 2 47 2.5E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS04265 55fd1807a209b724f32f6d274e982349 162 Pfam PF00877 NlpC/P60 family 65 158 6.3E-18 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain BWK49_RS04265 55fd1807a209b724f32f6d274e982349 162 SUPERFAMILY SSF54001 49 159 9.81E-30 T 06-07-2017 BWK49_RS04265 55fd1807a209b724f32f6d274e982349 162 Gene3D G3DSA:3.90.1720.10 53 159 3.0E-31 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain BWK49_RS15560 7abcd62487fcbddca88924c55e3b974a 401 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 343 352 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 BWK49_RS15560 7abcd62487fcbddca88924c55e3b974a 401 Pfam PF00067 Cytochrome P450 202 376 3.3E-22 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS15560 7abcd62487fcbddca88924c55e3b974a 401 PRINTS PR00385 P450 superfamily signature 274 285 1.3E-6 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS15560 7abcd62487fcbddca88924c55e3b974a 401 PRINTS PR00385 P450 superfamily signature 239 256 1.3E-6 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS15560 7abcd62487fcbddca88924c55e3b974a 401 PRINTS PR00385 P450 superfamily signature 341 350 1.3E-6 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS15560 7abcd62487fcbddca88924c55e3b974a 401 PRINTS PR00385 P450 superfamily signature 350 361 1.3E-6 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS15560 7abcd62487fcbddca88924c55e3b974a 401 Gene3D G3DSA:1.10.630.10 10 398 4.1E-107 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS15560 7abcd62487fcbddca88924c55e3b974a 401 SUPERFAMILY SSF48264 14 399 2.36E-89 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS15560 7abcd62487fcbddca88924c55e3b974a 401 PRINTS PR00359 B-class P450 signature 291 318 2.0E-31 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS15560 7abcd62487fcbddca88924c55e3b974a 401 PRINTS PR00359 B-class P450 signature 350 361 2.0E-31 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS15560 7abcd62487fcbddca88924c55e3b974a 401 PRINTS PR00359 B-class P450 signature 274 285 2.0E-31 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS15560 7abcd62487fcbddca88924c55e3b974a 401 PRINTS PR00359 B-class P450 signature 133 149 2.0E-31 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS15560 7abcd62487fcbddca88924c55e3b974a 401 PRINTS PR00359 B-class P450 signature 341 350 2.0E-31 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS15560 7abcd62487fcbddca88924c55e3b974a 401 PRINTS PR00359 B-class P450 signature 150 165 2.0E-31 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS15560 7abcd62487fcbddca88924c55e3b974a 401 PRINTS PR00359 B-class P450 signature 87 98 2.0E-31 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS15560 7abcd62487fcbddca88924c55e3b974a 401 PRINTS PR00359 B-class P450 signature 188 210 2.0E-31 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS09235 dc35f562ceac249e41c09a2c969315b8 508 Pfam PF00501 AMP-binding enzyme 8 414 1.2E-76 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS09235 dc35f562ceac249e41c09a2c969315b8 508 Gene3D G3DSA:3.30.300.30 411 505 3.4E-20 T 06-07-2017 BWK49_RS09235 dc35f562ceac249e41c09a2c969315b8 508 Gene3D G3DSA:2.30.38.10 339 405 5.6E-23 T 06-07-2017 BWK49_RS09235 dc35f562ceac249e41c09a2c969315b8 508 Pfam PF13193 AMP-binding enzyme C-terminal domain 423 496 8.3E-10 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS09235 dc35f562ceac249e41c09a2c969315b8 508 Gene3D G3DSA:3.40.50.980 2 183 1.9E-32 T 06-07-2017 BWK49_RS09235 dc35f562ceac249e41c09a2c969315b8 508 Gene3D G3DSA:3.40.50.980 184 338 6.5E-25 T 06-07-2017 BWK49_RS09235 dc35f562ceac249e41c09a2c969315b8 508 SUPERFAMILY SSF56801 2 506 1.44E-114 T 06-07-2017 BWK49_RS09235 dc35f562ceac249e41c09a2c969315b8 508 ProSitePatterns PS00455 Putative AMP-binding domain signature. 177 188 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS08130 0b6ab1dd438c8c68e547196d62c26894 360 Gene3D G3DSA:3.40.47.10 11 211 3.0E-44 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS08130 0b6ab1dd438c8c68e547196d62c26894 360 Gene3D G3DSA:3.40.47.10 219 360 2.2E-32 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS08130 0b6ab1dd438c8c68e547196d62c26894 360 SUPERFAMILY SSF53901 18 360 2.69E-43 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS08130 0b6ab1dd438c8c68e547196d62c26894 360 PIRSF PIRSF000451 7 360 2.0E-100 T 06-07-2017 IPR011141 Polyketide synthase, type III GO:0009058|GO:0016747 BWK49_RS08130 0b6ab1dd438c8c68e547196d62c26894 360 Pfam PF02797 Chalcone and stilbene synthases, C-terminal domain 226 357 8.1E-15 T 06-07-2017 IPR012328 Chalcone/stilbene synthase, C-terminal BWK49_RS08130 0b6ab1dd438c8c68e547196d62c26894 360 Pfam PF00195 Chalcone and stilbene synthases, N-terminal domain 84 205 9.8E-14 T 06-07-2017 IPR001099 Chalcone/stilbene synthase, N-terminal BWK49_RS08945 1333ac13128a2ef74b8c02ecded1583f 82 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 21 77 1.8E-14 T 06-07-2017 IPR005953 ATPase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 BWK49_RS08945 1333ac13128a2ef74b8c02ecded1583f 82 PRINTS PR00124 ATP synthase C subunit signature 50 75 1.6E-8 T 06-07-2017 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210 BWK49_RS08945 1333ac13128a2ef74b8c02ecded1583f 82 PRINTS PR00124 ATP synthase C subunit signature 33 48 1.6E-8 T 06-07-2017 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210 BWK49_RS08945 1333ac13128a2ef74b8c02ecded1583f 82 PRINTS PR00124 ATP synthase C subunit signature 12 31 1.6E-8 T 06-07-2017 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210 BWK49_RS08945 1333ac13128a2ef74b8c02ecded1583f 82 Gene3D G3DSA:1.20.20.10 5 79 1.3E-25 T 06-07-2017 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210 BWK49_RS08945 1333ac13128a2ef74b8c02ecded1583f 82 Pfam PF00137 ATP synthase subunit C 11 70 3.8E-9 T 06-07-2017 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 BWK49_RS08945 1333ac13128a2ef74b8c02ecded1583f 82 ProSitePatterns PS00605 ATP synthase c subunit signature. 40 61 - T 06-07-2017 IPR020537 ATPase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210 BWK49_RS08945 1333ac13128a2ef74b8c02ecded1583f 82 Hamap MF_01396 ATP synthase subunit c [atpH]. 9 77 14.825 T 06-07-2017 BWK49_RS08945 1333ac13128a2ef74b8c02ecded1583f 82 SUPERFAMILY SSF81333 5 78 2.62E-16 T 06-07-2017 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 BWK49_RS07365 723f72ddcef0c4ce0e8c2efd0cf83d5f 225 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 63 4.0E-12 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS07365 723f72ddcef0c4ce0e8c2efd0cf83d5f 225 SUPERFAMILY SSF46689 6 77 4.98E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS07365 723f72ddcef0c4ce0e8c2efd0cf83d5f 225 SUPERFAMILY SSF48498 84 211 5.82E-25 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS07365 723f72ddcef0c4ce0e8c2efd0cf83d5f 225 Gene3D G3DSA:1.10.357.10 7 195 4.4E-33 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS07365 723f72ddcef0c4ce0e8c2efd0cf83d5f 225 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 1.3E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS07365 723f72ddcef0c4ce0e8c2efd0cf83d5f 225 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 1.3E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS21375 b24bd1481190abf9ea8eaa86f113f40d 491 Gene3D G3DSA:1.10.630.10 55 490 1.9E-102 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS21375 b24bd1481190abf9ea8eaa86f113f40d 491 PRINTS PR00465 E-class P450 group IV signature 293 319 6.2E-21 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS21375 b24bd1481190abf9ea8eaa86f113f40d 491 PRINTS PR00465 E-class P450 group IV signature 348 364 6.2E-21 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS21375 b24bd1481190abf9ea8eaa86f113f40d 491 PRINTS PR00465 E-class P450 group IV signature 397 415 6.2E-21 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS21375 b24bd1481190abf9ea8eaa86f113f40d 491 PRINTS PR00465 E-class P450 group IV signature 438 456 6.2E-21 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS21375 b24bd1481190abf9ea8eaa86f113f40d 491 PRINTS PR00465 E-class P450 group IV signature 422 438 6.2E-21 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS21375 b24bd1481190abf9ea8eaa86f113f40d 491 PRINTS PR00465 E-class P450 group IV signature 381 395 6.2E-21 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS21375 b24bd1481190abf9ea8eaa86f113f40d 491 PRINTS PR00465 E-class P450 group IV signature 56 73 6.2E-21 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS21375 b24bd1481190abf9ea8eaa86f113f40d 491 SUPERFAMILY SSF48264 56 490 6.68E-105 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS21375 b24bd1481190abf9ea8eaa86f113f40d 491 Pfam PF00067 Cytochrome P450 62 465 4.0E-68 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS21375 b24bd1481190abf9ea8eaa86f113f40d 491 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 431 440 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 BWK49_RS23485 311c754be4cedb999881f37bc4bd2d3f 104 Pfam PF00893 Small Multidrug Resistance protein 1 91 7.7E-21 T 06-07-2017 IPR000390 Small multidrug resistance protein family GO:0016021 BWK49_RS23485 311c754be4cedb999881f37bc4bd2d3f 104 SUPERFAMILY SSF103481 5 102 6.41E-13 T 06-07-2017 BWK49_RS13895 284c699d4e15f654a28cc5057cb62f72 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 6.5E-14 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS13895 284c699d4e15f654a28cc5057cb62f72 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 6.5E-14 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS13895 284c699d4e15f654a28cc5057cb62f72 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 6.5E-14 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS13895 284c699d4e15f654a28cc5057cb62f72 260 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 239 1.9E-64 T 06-07-2017 BWK49_RS13895 284c699d4e15f654a28cc5057cb62f72 260 Gene3D G3DSA:3.40.50.720 4 248 1.0E-83 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS13895 284c699d4e15f654a28cc5057cb62f72 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 3.1E-44 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS13895 284c699d4e15f654a28cc5057cb62f72 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 3.1E-44 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS13895 284c699d4e15f654a28cc5057cb62f72 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 202 222 3.1E-44 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS13895 284c699d4e15f654a28cc5057cb62f72 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 3.1E-44 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS13895 284c699d4e15f654a28cc5057cb62f72 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 3.1E-44 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS13895 284c699d4e15f654a28cc5057cb62f72 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 3.1E-44 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS13895 284c699d4e15f654a28cc5057cb62f72 260 SUPERFAMILY SSF51735 7 240 5.07E-78 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS13895 284c699d4e15f654a28cc5057cb62f72 260 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS26200 123367eefde33a29ca2004deea03faee 218 Pfam PF08241 Methyltransferase domain 57 151 1.6E-23 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 BWK49_RS26200 123367eefde33a29ca2004deea03faee 218 Gene3D G3DSA:3.40.50.150 16 202 9.4E-38 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS26200 123367eefde33a29ca2004deea03faee 218 SUPERFAMILY SSF53335 15 208 1.04E-37 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS13505 2d482bd614fcdd943dded00b2ce2fcd2 453 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 293 442 1.6E-23 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS13505 2d482bd614fcdd943dded00b2ce2fcd2 453 SUPERFAMILY SSF88946 273 376 3.34E-22 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS13505 2d482bd614fcdd943dded00b2ce2fcd2 453 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 318 349 - T 06-07-2017 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS13505 2d482bd614fcdd943dded00b2ce2fcd2 453 Gene3D G3DSA:1.10.1740.10 274 380 1.6E-23 T 06-07-2017 BWK49_RS13505 2d482bd614fcdd943dded00b2ce2fcd2 453 Pfam PF08281 Sigma-70, region 4 391 442 7.8E-15 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS13505 2d482bd614fcdd943dded00b2ce2fcd2 453 Pfam PF13490 Putative zinc-finger 3 37 4.3E-9 T 06-07-2017 IPR027383 Putative zinc-finger BWK49_RS13505 2d482bd614fcdd943dded00b2ce2fcd2 453 Pfam PF10039 Predicted integral membrane protein (DUF2275) 56 235 7.4E-48 T 06-07-2017 IPR018734 Domain of unknown function DUF2275 BWK49_RS13505 2d482bd614fcdd943dded00b2ce2fcd2 453 Gene3D G3DSA:1.10.10.10 388 442 2.6E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS13505 2d482bd614fcdd943dded00b2ce2fcd2 453 SUPERFAMILY SSF88659 386 442 6.98E-13 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS13505 2d482bd614fcdd943dded00b2ce2fcd2 453 Pfam PF04542 Sigma-70 region 2 298 363 1.9E-15 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS23240 51f77acf341a2ab27f16a450506998ad 150 Gene3D G3DSA:1.10.10.10 3 56 1.4E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS23240 51f77acf341a2ab27f16a450506998ad 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 5 21 3.6E-9 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 BWK49_RS23240 51f77acf341a2ab27f16a450506998ad 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 51 3.6E-9 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 BWK49_RS23240 51f77acf341a2ab27f16a450506998ad 150 Pfam PF13404 AsnC-type helix-turn-helix domain 5 46 4.2E-9 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 BWK49_RS23240 51f77acf341a2ab27f16a450506998ad 150 Pfam PF01037 Lrp/AsnC ligand binding domain 78 140 1.3E-11 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain BWK49_RS23240 51f77acf341a2ab27f16a450506998ad 150 Gene3D G3DSA:3.30.70.920 58 138 3.9E-23 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain BWK49_RS23240 51f77acf341a2ab27f16a450506998ad 150 SMART SM00344 5 112 5.1E-38 T 06-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 BWK49_RS23240 51f77acf341a2ab27f16a450506998ad 150 SUPERFAMILY SSF46785 4 65 4.84E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS23240 51f77acf341a2ab27f16a450506998ad 150 SUPERFAMILY SSF54909 68 149 5.09E-12 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel BWK49_RS05230 4730b170cd03db35bf191af206323ebd 322 ProSitePatterns PS01173 Lipolytic enzymes "G-D-X-G" family, putative histidine active site. 90 106 - T 06-07-2017 IPR002168 Lipase, GDXG, putative histidine active site GO:0008152|GO:0016787 Reactome: R-HSA-163560 BWK49_RS05230 4730b170cd03db35bf191af206323ebd 322 SUPERFAMILY SSF53474 54 315 6.84E-53 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS05230 4730b170cd03db35bf191af206323ebd 322 Gene3D G3DSA:3.40.50.1820 29 313 2.3E-63 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS05230 4730b170cd03db35bf191af206323ebd 322 ProSitePatterns PS01174 Lipolytic enzymes "G-D-X-G" family, putative serine active site. 160 172 - T 06-07-2017 IPR033140 Lipase, GDXG, putative serine active site BWK49_RS05230 4730b170cd03db35bf191af206323ebd 322 Pfam PF07859 alpha/beta hydrolase fold 90 293 7.8E-56 T 06-07-2017 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 BWK49_RS19925 ad188be9f2cce90ba6f1591ba71b8966 348 SMART SM00316 110 182 0.0023 T 06-07-2017 IPR022967 RNA-binding domain, S1 BWK49_RS19925 ad188be9f2cce90ba6f1591ba71b8966 348 Pfam PF13184 NusA-like KH domain 214 282 4.9E-26 T 06-07-2017 IPR025249 KH domain, NusA-like GO:0003723 BWK49_RS19925 ad188be9f2cce90ba6f1591ba71b8966 348 SUPERFAMILY SSF54814 184 262 4.58E-27 T 06-07-2017 IPR009019 K homology domain, prokaryotic type GO:0003723 BWK49_RS19925 ad188be9f2cce90ba6f1591ba71b8966 348 Pfam PF08529 NusA N-terminal domain 6 61 6.8E-8 T 06-07-2017 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 BWK49_RS19925 ad188be9f2cce90ba6f1591ba71b8966 348 Pfam PF08529 NusA N-terminal domain 66 100 6.1E-6 T 06-07-2017 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 BWK49_RS19925 ad188be9f2cce90ba6f1591ba71b8966 348 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 1 348 25.846 T 06-07-2017 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 BWK49_RS19925 ad188be9f2cce90ba6f1591ba71b8966 348 Gene3D G3DSA:3.30.1480.10 2 99 4.0E-30 T 06-07-2017 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 BWK49_RS19925 ad188be9f2cce90ba6f1591ba71b8966 348 Gene3D G3DSA:3.30.300.20 183 261 1.3E-32 T 06-07-2017 IPR015946 K homology domain-like, alpha/beta BWK49_RS19925 ad188be9f2cce90ba6f1591ba71b8966 348 SUPERFAMILY SSF69705 1 99 4.84E-28 T 06-07-2017 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 BWK49_RS19925 ad188be9f2cce90ba6f1591ba71b8966 348 Gene3D G3DSA:3.30.300.20 262 326 2.0E-30 T 06-07-2017 IPR015946 K homology domain-like, alpha/beta BWK49_RS19925 ad188be9f2cce90ba6f1591ba71b8966 348 SUPERFAMILY SSF54814 263 327 9.16E-17 T 06-07-2017 IPR009019 K homology domain, prokaryotic type GO:0003723 BWK49_RS19925 ad188be9f2cce90ba6f1591ba71b8966 348 Gene3D G3DSA:2.40.50.140 106 182 2.3E-25 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS19925 ad188be9f2cce90ba6f1591ba71b8966 348 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 5 326 1.0E-108 T 06-07-2017 IPR010213 Transcription termination factor NusA GO:0003723 BWK49_RS19925 ad188be9f2cce90ba6f1591ba71b8966 348 SUPERFAMILY SSF50249 109 183 2.01E-15 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS19055 eea3a6c5e6a46b9923959fddc9613c67 223 Pfam PF09335 SNARE associated Golgi protein 32 161 1.4E-18 T 06-07-2017 IPR032816 SNARE associated Golgi protein BWK49_RS12565 a229ed4b60df7a7bd128946a5701d749 190 Gene3D G3DSA:2.60.120.10 95 182 1.2E-14 T 06-07-2017 IPR014710 RmlC-like jelly roll fold BWK49_RS12565 a229ed4b60df7a7bd128946a5701d749 190 Pfam PF01381 Helix-turn-helix 16 70 2.5E-15 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 BWK49_RS12565 a229ed4b60df7a7bd128946a5701d749 190 Pfam PF07883 Cupin domain 123 179 3.1E-11 T 06-07-2017 IPR013096 Cupin 2, conserved barrel BWK49_RS12565 a229ed4b60df7a7bd128946a5701d749 190 SUPERFAMILY SSF51182 69 178 3.27E-23 T 06-07-2017 IPR011051 RmlC-like cupin domain BWK49_RS12565 a229ed4b60df7a7bd128946a5701d749 190 Gene3D G3DSA:1.10.260.40 14 94 3.5E-20 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 BWK49_RS12565 a229ed4b60df7a7bd128946a5701d749 190 SUPERFAMILY SSF47413 7 74 8.73E-18 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 BWK49_RS12565 a229ed4b60df7a7bd128946a5701d749 190 SMART SM00530 15 70 8.5E-18 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 BWK49_RS27705 27192e55fe30de453e6808ee20b62b4d 348 Gene3D G3DSA:2.40.10.10 135 245 1.1E-21 T 06-07-2017 BWK49_RS27705 27192e55fe30de453e6808ee20b62b4d 348 PRINTS PR00834 HtrA/DegQ protease family signature 187 204 3.2E-27 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 BWK49_RS27705 27192e55fe30de453e6808ee20b62b4d 348 PRINTS PR00834 HtrA/DegQ protease family signature 209 226 3.2E-27 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 BWK49_RS27705 27192e55fe30de453e6808ee20b62b4d 348 PRINTS PR00834 HtrA/DegQ protease family signature 104 124 3.2E-27 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 BWK49_RS27705 27192e55fe30de453e6808ee20b62b4d 348 PRINTS PR00834 HtrA/DegQ protease family signature 82 94 3.2E-27 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 BWK49_RS27705 27192e55fe30de453e6808ee20b62b4d 348 PRINTS PR00834 HtrA/DegQ protease family signature 143 167 3.2E-27 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 BWK49_RS27705 27192e55fe30de453e6808ee20b62b4d 348 PRINTS PR00834 HtrA/DegQ protease family signature 290 302 3.2E-27 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 BWK49_RS27705 27192e55fe30de453e6808ee20b62b4d 348 Gene3D G3DSA:2.30.42.10 264 346 5.9E-16 T 06-07-2017 IPR001478 PDZ domain GO:0005515 BWK49_RS27705 27192e55fe30de453e6808ee20b62b4d 348 SUPERFAMILY SSF50156 272 346 1.28E-14 T 06-07-2017 IPR001478 PDZ domain GO:0005515 BWK49_RS27705 27192e55fe30de453e6808ee20b62b4d 348 Pfam PF13365 Trypsin-like peptidase domain 73 216 3.4E-27 T 06-07-2017 BWK49_RS27705 27192e55fe30de453e6808ee20b62b4d 348 SUPERFAMILY SSF50494 43 248 4.43E-42 T 06-07-2017 IPR009003 Peptidase S1, PA clan BWK49_RS27705 27192e55fe30de453e6808ee20b62b4d 348 SMART SM00228 261 332 6.1E-7 T 06-07-2017 IPR001478 PDZ domain GO:0005515 BWK49_RS27705 27192e55fe30de453e6808ee20b62b4d 348 Pfam PF13180 PDZ domain 262 342 8.0E-14 T 06-07-2017 IPR001478 PDZ domain GO:0005515 BWK49_RS27705 27192e55fe30de453e6808ee20b62b4d 348 Gene3D G3DSA:2.40.10.10 44 134 4.4E-22 T 06-07-2017 BWK49_RS16335 633192807ff7bc4bd7d01ba88fc0a24b 424 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 40 410 6.0E-99 T 06-07-2017 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase BWK49_RS16335 633192807ff7bc4bd7d01ba88fc0a24b 424 SUPERFAMILY SSF53383 16 413 8.43E-81 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase BWK49_RS16335 633192807ff7bc4bd7d01ba88fc0a24b 424 PIRSF PIRSF000390 10 418 1.9E-89 T 06-07-2017 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase BWK49_RS16335 633192807ff7bc4bd7d01ba88fc0a24b 424 Gene3D G3DSA:3.90.1150.10 271 416 5.5E-24 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 BWK49_RS16335 633192807ff7bc4bd7d01ba88fc0a24b 424 Gene3D G3DSA:3.40.640.10 23 270 7.2E-68 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 BWK49_RS16805 5d34eb6f96d2db49da5d2814df7c0200 161 Pfam PF04224 Protein of unknown function, DUF417 21 152 1.3E-34 T 06-07-2017 IPR007339 Protein of unknown function DUF417 BWK49_RS02180 25da99160782312aa9c21bd7219f3d90 238 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 45 209 3.8E-17 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS02180 25da99160782312aa9c21bd7219f3d90 238 SUPERFAMILY SSF161098 24 204 5.1E-30 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS02180 25da99160782312aa9c21bd7219f3d90 238 Gene3D G3DSA:1.10.3720.10 24 208 4.5E-23 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS03855 9c8c7eed215f104bf6e89c5c5faf8825 303 Pfam PF00756 Putative esterase 93 260 4.4E-6 T 06-07-2017 IPR000801 Putative esterase Reactome: R-HSA-156590 BWK49_RS03855 9c8c7eed215f104bf6e89c5c5faf8825 303 SUPERFAMILY SSF53474 62 298 1.07E-30 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS03855 9c8c7eed215f104bf6e89c5c5faf8825 303 Gene3D G3DSA:3.40.50.1820 71 298 4.9E-32 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS12355 bd89f37e6963e539cbf4b64c6a5d2bbe 180 Pfam PF07366 SnoaL-like polyketide cyclase 21 142 1.9E-14 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain BWK49_RS12355 bd89f37e6963e539cbf4b64c6a5d2bbe 180 SUPERFAMILY SSF54427 16 148 2.61E-23 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS12355 bd89f37e6963e539cbf4b64c6a5d2bbe 180 Gene3D G3DSA:3.10.450.50 19 142 2.1E-15 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS07970 7fab05f761e20fac804caf1573ebf5ae 469 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 10 458 7.9E-160 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 BWK49_RS07970 7fab05f761e20fac804caf1573ebf5ae 469 ProSitePatterns PS00069 Glucose-6-phosphate dehydrogenase active site. 171 177 - T 06-07-2017 IPR019796 Glucose-6-phosphate dehydrogenase, active site GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 BWK49_RS07970 7fab05f761e20fac804caf1573ebf5ae 469 SUPERFAMILY SSF55347 176 455 1.7E-89 T 06-07-2017 BWK49_RS07970 7fab05f761e20fac804caf1573ebf5ae 469 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 213 230 1.9E-43 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 BWK49_RS07970 7fab05f761e20fac804caf1573ebf5ae 469 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 137 150 1.9E-43 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 BWK49_RS07970 7fab05f761e20fac804caf1573ebf5ae 469 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 308 334 1.9E-43 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 BWK49_RS07970 7fab05f761e20fac804caf1573ebf5ae 469 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 231 247 1.9E-43 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 BWK49_RS07970 7fab05f761e20fac804caf1573ebf5ae 469 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 161 189 1.9E-43 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 BWK49_RS07970 7fab05f761e20fac804caf1573ebf5ae 469 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 9 458 76.717 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 BWK49_RS07970 7fab05f761e20fac804caf1573ebf5ae 469 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 13 180 2.8E-45 T 06-07-2017 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 BWK49_RS07970 7fab05f761e20fac804caf1573ebf5ae 469 SUPERFAMILY SSF51735 10 184 2.36E-43 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS07970 7fab05f761e20fac804caf1573ebf5ae 469 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 184 456 2.6E-88 T 06-07-2017 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 BWK49_RS07970 7fab05f761e20fac804caf1573ebf5ae 469 Gene3D G3DSA:3.30.360.10 181 456 4.1E-92 T 06-07-2017 BWK49_RS07970 7fab05f761e20fac804caf1573ebf5ae 469 Gene3D G3DSA:3.40.50.720 12 180 1.6E-49 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS07970 7fab05f761e20fac804caf1573ebf5ae 469 PIRSF PIRSF000110 3 460 2.1E-150 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 BWK49_RS14785 c50dd1aec9a588dc61b229bad7ee18a5 293 Gene3D G3DSA:3.20.20.30 10 288 2.8E-58 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS14785 c50dd1aec9a588dc61b229bad7ee18a5 293 TIGRFAM TIGR03854 F420_MSMEG_3544: probable F420-dependent oxidoreductase, MSMEG_3544 family 4 293 2.5E-154 T 06-07-2017 IPR022402 F420-dependent oxidoreductase-predicted, MSMEG3544 BWK49_RS14785 c50dd1aec9a588dc61b229bad7ee18a5 293 SUPERFAMILY SSF51679 3 288 1.16E-49 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS14785 c50dd1aec9a588dc61b229bad7ee18a5 293 Pfam PF00296 Luciferase-like monooxygenase 8 233 1.1E-37 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS24560 05e1e3e780d26af868962e0f6b3597e9 286 Gene3D G3DSA:3.40.50.150 7 286 1.7E-75 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS24560 05e1e3e780d26af868962e0f6b3597e9 286 SUPERFAMILY SSF53335 12 286 6.5E-68 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS24560 05e1e3e780d26af868962e0f6b3597e9 286 PIRSF PIRSF003085 5 286 2.4E-87 T 06-07-2017 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 BWK49_RS24560 05e1e3e780d26af868962e0f6b3597e9 286 Pfam PF02353 Mycolic acid cyclopropane synthetase 4 281 2.8E-101 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS11965 6be40741950e09b4469ae4e026a2769a 211 Gene3D G3DSA:3.40.50.150 12 199 3.3E-38 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS11965 6be40741950e09b4469ae4e026a2769a 211 Pfam PF13649 Methyltransferase domain 53 142 1.6E-21 T 06-07-2017 BWK49_RS11965 6be40741950e09b4469ae4e026a2769a 211 SUPERFAMILY SSF53335 9 198 1.17E-39 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS24780 c717aa7dd12ab5c1fc1a260db874315e 409 Gene3D G3DSA:1.10.630.10 14 408 2.3E-102 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS24780 c717aa7dd12ab5c1fc1a260db874315e 409 PRINTS PR00385 P450 superfamily signature 248 265 6.0E-7 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS24780 c717aa7dd12ab5c1fc1a260db874315e 409 PRINTS PR00385 P450 superfamily signature 283 294 6.0E-7 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS24780 c717aa7dd12ab5c1fc1a260db874315e 409 PRINTS PR00385 P450 superfamily signature 350 359 6.0E-7 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS24780 c717aa7dd12ab5c1fc1a260db874315e 409 PRINTS PR00385 P450 superfamily signature 359 370 6.0E-7 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS24780 c717aa7dd12ab5c1fc1a260db874315e 409 SUPERFAMILY SSF48264 27 407 4.19E-83 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS24780 c717aa7dd12ab5c1fc1a260db874315e 409 PRINTS PR00359 B-class P450 signature 350 359 2.1E-45 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS24780 c717aa7dd12ab5c1fc1a260db874315e 409 PRINTS PR00359 B-class P450 signature 158 173 2.1E-45 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS24780 c717aa7dd12ab5c1fc1a260db874315e 409 PRINTS PR00359 B-class P450 signature 202 224 2.1E-45 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS24780 c717aa7dd12ab5c1fc1a260db874315e 409 PRINTS PR00359 B-class P450 signature 141 157 2.1E-45 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS24780 c717aa7dd12ab5c1fc1a260db874315e 409 PRINTS PR00359 B-class P450 signature 95 106 2.1E-45 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS24780 c717aa7dd12ab5c1fc1a260db874315e 409 PRINTS PR00359 B-class P450 signature 328 343 2.1E-45 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS24780 c717aa7dd12ab5c1fc1a260db874315e 409 PRINTS PR00359 B-class P450 signature 300 327 2.1E-45 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS24780 c717aa7dd12ab5c1fc1a260db874315e 409 PRINTS PR00359 B-class P450 signature 283 294 2.1E-45 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS24780 c717aa7dd12ab5c1fc1a260db874315e 409 PRINTS PR00359 B-class P450 signature 359 370 2.1E-45 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS24780 c717aa7dd12ab5c1fc1a260db874315e 409 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 352 361 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 BWK49_RS24780 c717aa7dd12ab5c1fc1a260db874315e 409 Pfam PF00067 Cytochrome P450 95 375 3.9E-26 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS14180 30805b16443b9634a2b91a1b1bf48e17 118 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 18 79 2.2E-12 T 06-07-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM BWK49_RS14180 30805b16443b9634a2b91a1b1bf48e17 118 Gene3D G3DSA:3.40.1620.10 18 63 5.6E-8 T 06-07-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM BWK49_RS14180 30805b16443b9634a2b91a1b1bf48e17 118 SUPERFAMILY SSF143120 19 69 3.27E-10 T 06-07-2017 BWK49_RS14180 30805b16443b9634a2b91a1b1bf48e17 118 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 18 67 1.1E-11 T 06-07-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM BWK49_RS16715 bf199a70ae6c9142d562109b93f91a12 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 70 5.3E-16 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS16715 bf199a70ae6c9142d562109b93f91a12 207 Gene3D G3DSA:1.10.357.10 17 73 2.4E-22 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS16715 bf199a70ae6c9142d562109b93f91a12 207 Gene3D G3DSA:1.10.357.10 74 200 4.0E-38 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS16715 bf199a70ae6c9142d562109b93f91a12 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 24 37 1.2E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS16715 bf199a70ae6c9142d562109b93f91a12 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 68 1.2E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS16715 bf199a70ae6c9142d562109b93f91a12 207 SUPERFAMILY SSF46689 10 76 5.03E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS16715 bf199a70ae6c9142d562109b93f91a12 207 SUPERFAMILY SSF48498 89 200 4.89E-26 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS09980 63036d4965cf9bb5b13c1fad839b9e0e 136 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 114 122 - T 06-07-2017 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 BWK49_RS09980 63036d4965cf9bb5b13c1fad839b9e0e 136 Gene3D G3DSA:3.30.70.141 2 135 3.7E-56 T 06-07-2017 BWK49_RS09980 63036d4965cf9bb5b13c1fad839b9e0e 136 PRINTS PR01243 Nucleoside diphosphate kinase signature 49 68 6.2E-43 T 06-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 BWK49_RS09980 63036d4965cf9bb5b13c1fad839b9e0e 136 PRINTS PR01243 Nucleoside diphosphate kinase signature 91 107 6.2E-43 T 06-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 BWK49_RS09980 63036d4965cf9bb5b13c1fad839b9e0e 136 PRINTS PR01243 Nucleoside diphosphate kinase signature 114 133 6.2E-43 T 06-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 BWK49_RS09980 63036d4965cf9bb5b13c1fad839b9e0e 136 PRINTS PR01243 Nucleoside diphosphate kinase signature 5 27 6.2E-43 T 06-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 BWK49_RS09980 63036d4965cf9bb5b13c1fad839b9e0e 136 PRINTS PR01243 Nucleoside diphosphate kinase signature 69 86 6.2E-43 T 06-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 BWK49_RS09980 63036d4965cf9bb5b13c1fad839b9e0e 136 Pfam PF00334 Nucleoside diphosphate kinase 3 135 4.3E-52 T 06-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 BWK49_RS09980 63036d4965cf9bb5b13c1fad839b9e0e 136 SMART SM00562 2 136 6.0E-77 T 06-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 BWK49_RS09980 63036d4965cf9bb5b13c1fad839b9e0e 136 SUPERFAMILY SSF54919 2 135 2.36E-54 T 06-07-2017 BWK49_RS09980 63036d4965cf9bb5b13c1fad839b9e0e 136 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 2 136 33.379 T 06-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 BWK49_RS23370 d6074dee4bcffe65c4073c10282c2c9b 234 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 3 205 1.7E-74 T 06-07-2017 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 BWK49_RS23370 d6074dee4bcffe65c4073c10282c2c9b 234 SUPERFAMILY SSF53271 3 205 3.15E-57 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like BWK49_RS23370 d6074dee4bcffe65c4073c10282c2c9b 234 Pfam PF14681 Uracil phosphoribosyltransferase 5 205 3.2E-61 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like BWK49_RS23370 d6074dee4bcffe65c4073c10282c2c9b 234 Gene3D G3DSA:3.40.50.2020 3 205 3.4E-68 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like BWK49_RS23370 d6074dee4bcffe65c4073c10282c2c9b 234 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 2 207 40.198 T 06-07-2017 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 BWK49_RS10090 bb6a36b43e01d3695dae24ff729b495e 970 Pfam PF03176 MMPL family 637 958 1.3E-93 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 BWK49_RS10090 bb6a36b43e01d3695dae24ff729b495e 970 Pfam PF03176 MMPL family 80 407 2.1E-104 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 BWK49_RS10090 bb6a36b43e01d3695dae24ff729b495e 970 SUPERFAMILY SSF82866 726 954 2.09E-30 T 06-07-2017 BWK49_RS10090 bb6a36b43e01d3695dae24ff729b495e 970 Gene3D G3DSA:1.20.1640.10 756 955 1.4E-24 T 06-07-2017 BWK49_RS10090 bb6a36b43e01d3695dae24ff729b495e 970 Gene3D G3DSA:1.20.1640.10 176 382 1.3E-24 T 06-07-2017 BWK49_RS10090 bb6a36b43e01d3695dae24ff729b495e 970 TIGRFAM TIGR00833 actII: transport protein 47 954 6.2E-284 T 06-07-2017 IPR004707 Membrane transport protein MmpL family GO:0016021 BWK49_RS10090 bb6a36b43e01d3695dae24ff729b495e 970 SUPERFAMILY SSF82866 178 374 2.22E-25 T 06-07-2017 BWK49_RS05735 b11c2265bddb9073ea863b052d714ea8 279 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 275 2.0E-50 T 06-07-2017 BWK49_RS05735 b11c2265bddb9073ea863b052d714ea8 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.5E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05735 b11c2265bddb9073ea863b052d714ea8 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 161 1.5E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05735 b11c2265bddb9073ea863b052d714ea8 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 190 1.5E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05735 b11c2265bddb9073ea863b052d714ea8 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 192 209 1.5E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05735 b11c2265bddb9073ea863b052d714ea8 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 96 107 1.5E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05735 b11c2265bddb9073ea863b052d714ea8 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 240 260 1.5E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05735 b11c2265bddb9073ea863b052d714ea8 279 TIGRFAM TIGR03971 SDR_subfam_1: SDR family mycofactocin-dependent oxidoreductase 5 278 5.9E-120 T 06-07-2017 IPR023985 Mycofactocin-dependent oxidoreductase BWK49_RS05735 b11c2265bddb9073ea863b052d714ea8 279 Gene3D G3DSA:3.40.50.720 3 277 7.5E-74 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS05735 b11c2265bddb9073ea863b052d714ea8 279 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 96 107 1.2E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05735 b11c2265bddb9073ea863b052d714ea8 279 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 159 1.2E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05735 b11c2265bddb9073ea863b052d714ea8 279 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 171 190 1.2E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05735 b11c2265bddb9073ea863b052d714ea8 279 SUPERFAMILY SSF51735 6 277 1.67E-68 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS17195 8998fc77e23857fad35b458a913dcb42 204 Gene3D G3DSA:3.40.50.2300 8 131 1.9E-38 T 06-07-2017 BWK49_RS17195 8998fc77e23857fad35b458a913dcb42 204 Pfam PF03861 ANTAR domain 144 195 1.2E-18 T 06-07-2017 IPR005561 ANTAR domain GO:0003723 BWK49_RS17195 8998fc77e23857fad35b458a913dcb42 204 Gene3D G3DSA:1.10.10.10 144 201 2.3E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS17195 8998fc77e23857fad35b458a913dcb42 204 PIRSF PIRSF036382 5 203 6.2E-74 T 06-07-2017 IPR008327 Signal transduction response regulator, antiterminator BWK49_RS17195 8998fc77e23857fad35b458a913dcb42 204 SMART SM00448 14 125 3.1E-39 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 BWK49_RS17195 8998fc77e23857fad35b458a913dcb42 204 SUPERFAMILY SSF52172 12 196 1.85E-57 T 06-07-2017 IPR011006 CheY-like superfamily BWK49_RS17195 8998fc77e23857fad35b458a913dcb42 204 Pfam PF00072 Response regulator receiver domain 16 125 2.9E-30 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 BWK49_RS17195 8998fc77e23857fad35b458a913dcb42 204 SMART SM01012 141 196 1.4E-21 T 06-07-2017 IPR005561 ANTAR domain GO:0003723 BWK49_RS07770 6bc23e2137eaf71de3c6a66c6bb35f7c 257 TIGRFAM TIGR01065 hlyIII: channel protein, hemolysin III family 38 244 1.9E-60 T 06-07-2017 IPR005744 Hly-III GO:0016021|GO:0019835 BWK49_RS07770 6bc23e2137eaf71de3c6a66c6bb35f7c 257 Pfam PF03006 Haemolysin-III related 37 238 8.7E-42 T 06-07-2017 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 BWK49_RS25995 9420ed46be20176ee0897d10c666c624 398 SUPERFAMILY SSF52440 27 123 1.32E-19 T 06-07-2017 IPR016185 Pre-ATP-grasp domain BWK49_RS25995 9420ed46be20176ee0897d10c666c624 398 SUPERFAMILY SSF56059 125 329 5.13E-42 T 06-07-2017 BWK49_RS25995 9420ed46be20176ee0897d10c666c624 398 Pfam PF02222 ATP-grasp domain 135 309 1.9E-28 T 06-07-2017 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type BWK49_RS25995 9420ed46be20176ee0897d10c666c624 398 Gene3D G3DSA:3.30.470.20 210 390 6.6E-35 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 BWK49_RS25995 9420ed46be20176ee0897d10c666c624 398 Gene3D G3DSA:3.30.1490.20 136 209 4.3E-17 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 BWK49_RS25995 9420ed46be20176ee0897d10c666c624 398 Gene3D G3DSA:3.40.50.20 27 132 3.6E-26 T 06-07-2017 IPR016185 Pre-ATP-grasp domain BWK49_RS08255 e45591af7b57f6148a64ac432b8d1b67 539 Gene3D G3DSA:1.10.3650.10 358 436 4.3E-27 T 06-07-2017 IPR029263 Respiratory nitrate reductase beta, C-terminal KEGG: 00910+1.7.99.4 BWK49_RS08255 e45591af7b57f6148a64ac432b8d1b67 539 Pfam PF13247 4Fe-4S dicluster domain 174 270 1.4E-36 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain BWK49_RS08255 e45591af7b57f6148a64ac432b8d1b67 539 TIGRFAM TIGR01660 narH: nitrate reductase, beta subunit 1 483 1.5E-231 T 06-07-2017 IPR006547 Nitrate reductase, beta subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.99.4 BWK49_RS08255 e45591af7b57f6148a64ac432b8d1b67 539 Gene3D G3DSA:3.30.70.20 195 234 5.6E-25 T 06-07-2017 BWK49_RS08255 e45591af7b57f6148a64ac432b8d1b67 539 Pfam PF14711 Respiratory nitrate reductase beta C-terminal 357 438 6.3E-28 T 06-07-2017 IPR029263 Respiratory nitrate reductase beta, C-terminal KEGG: 00910+1.7.99.4 BWK49_RS08255 e45591af7b57f6148a64ac432b8d1b67 539 Gene3D G3DSA:3.30.70.20 10 26 1.0E-10 T 06-07-2017 BWK49_RS08255 e45591af7b57f6148a64ac432b8d1b67 539 Gene3D G3DSA:3.30.70.20 173 194 1.0E-10 T 06-07-2017 BWK49_RS08255 e45591af7b57f6148a64ac432b8d1b67 539 Gene3D G3DSA:3.30.70.20 125 126 1.0E-10 T 06-07-2017 BWK49_RS08255 e45591af7b57f6148a64ac432b8d1b67 539 SUPERFAMILY SSF54862 1 471 1.15E-160 T 06-07-2017 BWK49_RS08255 e45591af7b57f6148a64ac432b8d1b67 539 Gene3D G3DSA:3.30.70.20 235 357 1.8E-69 T 06-07-2017 BWK49_RS08255 e45591af7b57f6148a64ac432b8d1b67 539 Gene3D G3DSA:3.30.70.20 438 462 1.8E-69 T 06-07-2017 BWK49_RS11080 64c5d97bbb5d90ef1c22ab16d565f247 507 Pfam PF00501 AMP-binding enzyme 23 396 8.9E-55 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS11080 64c5d97bbb5d90ef1c22ab16d565f247 507 Gene3D G3DSA:3.40.50.980 166 314 5.5E-24 T 06-07-2017 BWK49_RS11080 64c5d97bbb5d90ef1c22ab16d565f247 507 Gene3D G3DSA:2.30.38.10 338 390 6.1E-9 T 06-07-2017 BWK49_RS11080 64c5d97bbb5d90ef1c22ab16d565f247 507 Pfam PF13193 AMP-binding enzyme C-terminal domain 405 482 9.8E-12 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS11080 64c5d97bbb5d90ef1c22ab16d565f247 507 Gene3D G3DSA:3.40.50.980 17 165 2.4E-26 T 06-07-2017 BWK49_RS11080 64c5d97bbb5d90ef1c22ab16d565f247 507 SUPERFAMILY SSF56801 15 493 2.88E-96 T 06-07-2017 BWK49_RS11080 64c5d97bbb5d90ef1c22ab16d565f247 507 Gene3D G3DSA:3.30.300.30 391 491 1.2E-21 T 06-07-2017 BWK49_RS26415 f4355581844d9d5255588fc9fef84985 469 Pfam PF00082 Subtilase family 90 396 1.4E-34 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 BWK49_RS26415 f4355581844d9d5255588fc9fef84985 469 PRINTS PR00723 Subtilisin serine protease family (S8) signature 126 139 2.4E-11 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related BWK49_RS26415 f4355581844d9d5255588fc9fef84985 469 PRINTS PR00723 Subtilisin serine protease family (S8) signature 346 362 2.4E-11 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related BWK49_RS26415 f4355581844d9d5255588fc9fef84985 469 PRINTS PR00723 Subtilisin serine protease family (S8) signature 90 109 2.4E-11 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related BWK49_RS26415 f4355581844d9d5255588fc9fef84985 469 Gene3D G3DSA:3.40.50.200 75 405 6.4E-61 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 BWK49_RS26415 f4355581844d9d5255588fc9fef84985 469 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 130 140 - T 06-07-2017 IPR022398 Peptidase S8, subtilisin, His-active site BWK49_RS26415 f4355581844d9d5255588fc9fef84985 469 TIGRFAM TIGR03921 T7SS_mycosin: type VII secretion-associated serine protease mycosin 79 464 5.8E-114 T 06-07-2017 IPR023834 Type VII secretion system peptidase S8A, mycosin-1 BWK49_RS26415 f4355581844d9d5255588fc9fef84985 469 SUPERFAMILY SSF52743 277 405 2.49E-55 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 BWK49_RS26415 f4355581844d9d5255588fc9fef84985 469 SUPERFAMILY SSF52743 76 246 2.49E-55 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 BWK49_RS14430 31e2c35dddae18729ad7a9504b6a4da3 99 SUPERFAMILY SSF140459 8 84 4.97E-20 T 06-07-2017 BWK49_RS14430 31e2c35dddae18729ad7a9504b6a4da3 99 Pfam PF00934 PE family 1 93 7.7E-27 T 06-07-2017 IPR000084 PE-PGRS family, N-terminal BWK49_RS24430 12fb1e0db0f0e20cb5b95831c7dca03f 156 Gene3D G3DSA:1.10.455.10 8 156 3.3E-64 T 06-07-2017 IPR023798 Ribosomal protein S7 domain BWK49_RS24430 12fb1e0db0f0e20cb5b95831c7dca03f 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 5.6E-63 T 06-07-2017 IPR023798 Ribosomal protein S7 domain BWK49_RS24430 12fb1e0db0f0e20cb5b95831c7dca03f 156 SUPERFAMILY SSF47973 1 149 1.57E-59 T 06-07-2017 IPR023798 Ribosomal protein S7 domain BWK49_RS24430 12fb1e0db0f0e20cb5b95831c7dca03f 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 2.2E-68 T 06-07-2017 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 BWK49_RS24430 12fb1e0db0f0e20cb5b95831c7dca03f 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 36.003 T 06-07-2017 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 BWK49_RS24430 12fb1e0db0f0e20cb5b95831c7dca03f 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 06-07-2017 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 BWK49_RS24430 12fb1e0db0f0e20cb5b95831c7dca03f 156 PIRSF PIRSF002122 4 156 8.7E-58 T 06-07-2017 IPR000235 Ribosomal protein S5/S7 GO:0006412 BWK49_RS11780 72b4a2a0437e5f25c10d1b6af67f79f9 376 PIRSF PIRSF001112 1 373 8.3E-104 T 06-07-2017 IPR016292 Epoxide hydrolase GO:0033961 KEGG: 00980+3.3.2.9|Reactome: R-HSA-211945 BWK49_RS11780 72b4a2a0437e5f25c10d1b6af67f79f9 376 Gene3D G3DSA:3.40.50.1820 2 364 2.4E-126 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS11780 72b4a2a0437e5f25c10d1b6af67f79f9 376 SUPERFAMILY SSF53474 2 363 3.68E-87 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS11780 72b4a2a0437e5f25c10d1b6af67f79f9 376 Pfam PF06441 Epoxide hydrolase N terminus 2 106 1.1E-27 T 06-07-2017 IPR010497 Epoxide hydrolase, N-terminal KEGG: 00980+3.3.2.9|Reactome: R-HSA-211945 BWK49_RS11780 72b4a2a0437e5f25c10d1b6af67f79f9 376 PRINTS PR00412 Epoxide hydrolase signature 344 366 1.5E-12 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS11780 72b4a2a0437e5f25c10d1b6af67f79f9 376 PRINTS PR00412 Epoxide hydrolase signature 313 329 1.5E-12 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS11780 72b4a2a0437e5f25c10d1b6af67f79f9 376 PRINTS PR00412 Epoxide hydrolase signature 161 174 1.5E-12 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS11780 72b4a2a0437e5f25c10d1b6af67f79f9 376 PRINTS PR00412 Epoxide hydrolase signature 97 115 1.5E-12 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS22805 8c327411ca36dee5370302b50154640f 414 Pfam PF00753 Metallo-beta-lactamase superfamily 33 242 6.7E-11 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS22805 8c327411ca36dee5370302b50154640f 414 Pfam PF14863 Alkyl sulfatase dimerisation 291 411 3.5E-16 T 06-07-2017 IPR029228 Alkyl sulfatase dimerisation domain GO:0046983 BWK49_RS22805 8c327411ca36dee5370302b50154640f 414 Gene3D G3DSA:3.60.15.10 149 270 1.5E-40 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS22805 8c327411ca36dee5370302b50154640f 414 Gene3D G3DSA:3.60.15.10 25 112 1.5E-40 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS22805 8c327411ca36dee5370302b50154640f 414 SMART SM00849 35 242 1.2E-16 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS22805 8c327411ca36dee5370302b50154640f 414 SUPERFAMILY SSF56281 22 412 1.23E-71 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS02350 c27b8aef758cb11878081d847703c1f0 161 ProSitePatterns PS00893 Nudix box signature. 43 64 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 BWK49_RS02350 c27b8aef758cb11878081d847703c1f0 161 Gene3D G3DSA:3.90.79.10 3 144 7.6E-27 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 BWK49_RS02350 c27b8aef758cb11878081d847703c1f0 161 Pfam PF00293 NUDIX domain 4 146 3.0E-13 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 BWK49_RS02350 c27b8aef758cb11878081d847703c1f0 161 SUPERFAMILY SSF55811 4 149 3.38E-17 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 BWK49_RS21800 79d624a5459bedd34b77101d5cb3e5fa 254 Pfam PF05241 Emopamil binding protein 89 246 6.7E-6 T 06-07-2017 IPR007905 Emopamil-binding protein GO:0016021|GO:0016125|GO:0047750 BWK49_RS21540 7808df9b4f21f952c04e34df5445a44a 420 Gene3D G3DSA:3.90.380.10 159 345 1.6E-20 T 06-07-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 BWK49_RS21540 7808df9b4f21f952c04e34df5445a44a 420 SUPERFAMILY SSF55961 172 411 2.67E-39 T 06-07-2017 BWK49_RS21540 7808df9b4f21f952c04e34df5445a44a 420 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 31 56 1.2E-7 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS21540 7808df9b4f21f952c04e34df5445a44a 420 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 152 178 1.2E-7 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS21540 7808df9b4f21f952c04e34df5445a44a 420 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 84 104 1.2E-7 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS21540 7808df9b4f21f952c04e34df5445a44a 420 SUPERFAMILY SSF50022 12 167 1.7E-42 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS21540 7808df9b4f21f952c04e34df5445a44a 420 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 190 409 3.9E-51 T 06-07-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 BWK49_RS21540 7808df9b4f21f952c04e34df5445a44a 420 Gene3D G3DSA:2.102.10.10 46 158 2.3E-24 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS21540 7808df9b4f21f952c04e34df5445a44a 420 Pfam PF00355 Rieske [2Fe-2S] domain 47 137 2.3E-14 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS07115 0bdb3258e6346ef6978579e81441631f 199 Gene3D G3DSA:3.40.50.10420 6 191 9.5E-41 T 06-07-2017 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain BWK49_RS07115 0bdb3258e6346ef6978579e81441631f 199 PIRSF PIRSF006806 1 192 8.4E-47 T 06-07-2017 IPR002698 5-formyltetrahydrofolate cyclo-ligase BWK49_RS07115 0bdb3258e6346ef6978579e81441631f 199 SUPERFAMILY SSF100950 5 192 2.23E-36 T 06-07-2017 BWK49_RS07115 0bdb3258e6346ef6978579e81441631f 199 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 6 189 1.8E-35 T 06-07-2017 IPR002698 5-formyltetrahydrofolate cyclo-ligase BWK49_RS07115 0bdb3258e6346ef6978579e81441631f 199 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 6 189 4.9E-43 T 06-07-2017 IPR002698 5-formyltetrahydrofolate cyclo-ligase BWK49_RS11260 3baaef0712fdb7a6e107fe3659c1afcb 315 SUPERFAMILY SSF46689 16 101 9.5E-7 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS11260 3baaef0712fdb7a6e107fe3659c1afcb 315 Pfam PF00665 Integrase core domain 128 264 8.0E-31 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 BWK49_RS11260 3baaef0712fdb7a6e107fe3659c1afcb 315 Gene3D G3DSA:3.30.420.10 124 301 1.5E-41 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS11260 3baaef0712fdb7a6e107fe3659c1afcb 315 SUPERFAMILY SSF53098 130 305 2.78E-33 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS11260 3baaef0712fdb7a6e107fe3659c1afcb 315 Pfam PF13565 Homeodomain-like domain 33 99 1.3E-10 T 06-07-2017 BWK49_RS25655 ec987ee2a78bf0d7518ad4eeb0496aba 414 SUPERFAMILY SSF103473 24 393 2.22E-36 T 06-07-2017 IPR020846 Major facilitator superfamily domain BWK49_RS25655 ec987ee2a78bf0d7518ad4eeb0496aba 414 Pfam PF07690 Major Facilitator Superfamily 34 338 4.1E-13 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 BWK49_RS25655 ec987ee2a78bf0d7518ad4eeb0496aba 414 Gene3D G3DSA:1.20.1250.20 220 393 2.2E-12 T 06-07-2017 BWK49_RS25655 ec987ee2a78bf0d7518ad4eeb0496aba 414 Gene3D G3DSA:1.20.1250.20 30 196 3.4E-10 T 06-07-2017 BWK49_RS08360 c9d36b7d74e0f13df770fa5c8a8f9a7b 578 Pfam PF00501 AMP-binding enzyme 11 466 5.9E-74 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS08360 c9d36b7d74e0f13df770fa5c8a8f9a7b 578 Gene3D G3DSA:3.40.50.980 175 340 2.3E-23 T 06-07-2017 BWK49_RS08360 c9d36b7d74e0f13df770fa5c8a8f9a7b 578 Gene3D G3DSA:2.30.38.10 381 457 5.4E-21 T 06-07-2017 BWK49_RS08360 c9d36b7d74e0f13df770fa5c8a8f9a7b 578 Gene3D G3DSA:3.30.300.30 458 565 7.2E-14 T 06-07-2017 BWK49_RS08360 c9d36b7d74e0f13df770fa5c8a8f9a7b 578 SUPERFAMILY SSF56801 5 571 1.31E-94 T 06-07-2017 BWK49_RS08360 c9d36b7d74e0f13df770fa5c8a8f9a7b 578 Gene3D G3DSA:3.40.50.980 3 174 7.6E-26 T 06-07-2017 BWK49_RS23985 058afb45825ea54fa26fc5528ca9d005 211 SMART SM01110 30 211 1.2E-93 T 06-07-2017 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 BWK49_RS23985 058afb45825ea54fa26fc5528ca9d005 211 Gene3D G3DSA:3.40.50.1820 31 210 3.8E-55 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS23985 058afb45825ea54fa26fc5528ca9d005 211 Pfam PF01083 Cutinase 31 210 1.5E-53 T 06-07-2017 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 BWK49_RS23985 058afb45825ea54fa26fc5528ca9d005 211 ProSitePatterns PS00155 Cutinase, serine active site. 103 115 - T 06-07-2017 IPR011150 Cutinase, monofunctional GO:0005576|GO:0050525 BWK49_RS23985 058afb45825ea54fa26fc5528ca9d005 211 SUPERFAMILY SSF53474 31 210 1.25E-38 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS22065 ad1b2449ac4e31aefcaca056cff5c3ae 418 Pfam PF01882 Protein of unknown function DUF58 187 269 2.9E-17 T 06-07-2017 IPR002881 Domain of unknown function DUF58 BWK49_RS06120 1124031ff042cc19292a33ee62d3c156 424 SUPERFAMILY SSF48264 14 422 9.3E-83 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS06120 1124031ff042cc19292a33ee62d3c156 424 PRINTS PR00359 B-class P450 signature 305 332 3.8E-40 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS06120 1124031ff042cc19292a33ee62d3c156 424 PRINTS PR00359 B-class P450 signature 288 299 3.8E-40 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS06120 1124031ff042cc19292a33ee62d3c156 424 PRINTS PR00359 B-class P450 signature 206 228 3.8E-40 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS06120 1124031ff042cc19292a33ee62d3c156 424 PRINTS PR00359 B-class P450 signature 333 348 3.8E-40 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS06120 1124031ff042cc19292a33ee62d3c156 424 PRINTS PR00359 B-class P450 signature 355 364 3.8E-40 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS06120 1124031ff042cc19292a33ee62d3c156 424 PRINTS PR00359 B-class P450 signature 148 164 3.8E-40 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS06120 1124031ff042cc19292a33ee62d3c156 424 PRINTS PR00359 B-class P450 signature 364 375 3.8E-40 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS06120 1124031ff042cc19292a33ee62d3c156 424 PRINTS PR00359 B-class P450 signature 102 113 3.8E-40 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS06120 1124031ff042cc19292a33ee62d3c156 424 PRINTS PR00359 B-class P450 signature 165 180 3.8E-40 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS06120 1124031ff042cc19292a33ee62d3c156 424 Gene3D G3DSA:1.10.630.10 11 422 2.5E-101 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS06120 1124031ff042cc19292a33ee62d3c156 424 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 357 366 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 BWK49_RS06120 1124031ff042cc19292a33ee62d3c156 424 Pfam PF00067 Cytochrome P450 232 384 4.9E-21 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS17850 737c964f3a461a5d3313a0ff37ee9820 144 SUPERFAMILY SSF141322 78 141 2.48E-7 T 06-07-2017 BWK49_RS17850 737c964f3a461a5d3313a0ff37ee9820 144 Pfam PF01957 NfeD-like C-terminal, partner-binding 6 142 7.4E-27 T 06-07-2017 IPR002810 NfeD-like, C-terminal domain BWK49_RS17850 737c964f3a461a5d3313a0ff37ee9820 144 Gene3D G3DSA:2.40.50.140 81 141 1.7E-23 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS20660 afcf5d3b400995570c19ca5e142a057d 393 Gene3D G3DSA:3.40.50.1100 19 123 1.3E-8 T 06-07-2017 BWK49_RS20660 afcf5d3b400995570c19ca5e142a057d 393 Gene3D G3DSA:3.40.50.1100 6 18 0.001 T 06-07-2017 BWK49_RS20660 afcf5d3b400995570c19ca5e142a057d 393 Gene3D G3DSA:3.40.50.1100 128 175 0.001 T 06-07-2017 BWK49_RS20660 afcf5d3b400995570c19ca5e142a057d 393 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 6 175 1.6E-14 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme BWK49_RS20660 afcf5d3b400995570c19ca5e142a057d 393 SUPERFAMILY SSF53686 5 175 2.45E-20 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme BWK49_RS20660 afcf5d3b400995570c19ca5e142a057d 393 SUPERFAMILY SSF103473 178 322 8.11E-10 T 06-07-2017 IPR020846 Major facilitator superfamily domain BWK49_RS20660 afcf5d3b400995570c19ca5e142a057d 393 Gene3D G3DSA:1.20.1250.20 190 312 4.1E-4 T 06-07-2017 BWK49_RS23855 62444192aa43cf9a3b60df9685ea9544 163 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 17 144 1.5E-18 T 06-07-2017 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 BWK49_RS23855 62444192aa43cf9a3b60df9685ea9544 163 SUPERFAMILY SSF52540 28 97 2.01E-12 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS23855 62444192aa43cf9a3b60df9685ea9544 163 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 14 143 3.9E-28 T 06-07-2017 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 BWK49_RS23855 62444192aa43cf9a3b60df9685ea9544 163 Gene3D G3DSA:3.40.50.300 10 159 2.6E-41 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS04430 fe08fe7544a23b374d198a7bad7866a6 545 SUPERFAMILY SSF52743 71 146 4.37E-46 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 BWK49_RS04430 fe08fe7544a23b374d198a7bad7866a6 545 SUPERFAMILY SSF52743 232 483 4.37E-46 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 BWK49_RS04430 fe08fe7544a23b374d198a7bad7866a6 545 Gene3D G3DSA:3.40.50.200 231 483 2.3E-58 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 BWK49_RS04430 fe08fe7544a23b374d198a7bad7866a6 545 Gene3D G3DSA:3.40.50.200 63 145 2.3E-58 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 BWK49_RS04430 fe08fe7544a23b374d198a7bad7866a6 545 Pfam PF00082 Subtilase family 272 474 2.3E-19 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 BWK49_RS04430 fe08fe7544a23b374d198a7bad7866a6 545 PRINTS PR00723 Subtilisin serine protease family (S8) signature 126 139 1.4E-8 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related BWK49_RS04430 fe08fe7544a23b374d198a7bad7866a6 545 PRINTS PR00723 Subtilisin serine protease family (S8) signature 88 107 1.4E-8 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related BWK49_RS04430 fe08fe7544a23b374d198a7bad7866a6 545 PRINTS PR00723 Subtilisin serine protease family (S8) signature 424 440 1.4E-8 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related BWK49_RS23440 91467cc540266c865e6331f0dc4ba534 265 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 30 258 4.6E-72 T 06-07-2017 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 BWK49_RS23440 91467cc540266c865e6331f0dc4ba534 265 SUPERFAMILY SSF46548 137 262 1.24E-33 T 06-07-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 BWK49_RS23440 91467cc540266c865e6331f0dc4ba534 265 Gene3D G3DSA:3.10.20.30 21 136 3.8E-35 T 06-07-2017 IPR012675 Beta-grasp domain BWK49_RS23440 91467cc540266c865e6331f0dc4ba534 265 Pfam PF13183 4Fe-4S dicluster domain 176 248 2.0E-11 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain BWK49_RS23440 91467cc540266c865e6331f0dc4ba534 265 Gene3D G3DSA:1.10.1060.10 137 262 7.9E-39 T 06-07-2017 BWK49_RS23440 91467cc540266c865e6331f0dc4ba534 265 SUPERFAMILY SSF54292 24 136 1.81E-23 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 BWK49_RS23440 91467cc540266c865e6331f0dc4ba534 265 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 27 141 1.5E-30 T 06-07-2017 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 BWK49_RS23440 91467cc540266c865e6331f0dc4ba534 265 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 178 189 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site BWK49_RS26285 7609d8e82a60baad451a59ac797a1370 479 PIRSF PIRSF000538 1 457 4.0E-74 T 06-07-2017 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 BWK49_RS26285 7609d8e82a60baad451a59ac797a1370 479 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 335 356 - T 06-07-2017 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 BWK49_RS26285 7609d8e82a60baad451a59ac797a1370 479 SUPERFAMILY SSF53067 236 459 5.94E-44 T 06-07-2017 BWK49_RS26285 7609d8e82a60baad451a59ac797a1370 479 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 241 423 1.5E-25 T 06-07-2017 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 BWK49_RS26285 7609d8e82a60baad451a59ac797a1370 479 Gene3D G3DSA:3.30.420.40 236 445 5.2E-30 T 06-07-2017 BWK49_RS26285 7609d8e82a60baad451a59ac797a1370 479 Gene3D G3DSA:3.30.420.40 1 232 1.3E-40 T 06-07-2017 BWK49_RS26285 7609d8e82a60baad451a59ac797a1370 479 SUPERFAMILY SSF53067 4 235 5.18E-43 T 06-07-2017 BWK49_RS26285 7609d8e82a60baad451a59ac797a1370 479 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 4 217 5.4E-38 T 06-07-2017 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 BWK49_RS22745 7a9cd3ea58045d10db625ef193ebb75f 84 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 76 18.409 T 06-07-2017 IPR003482 Transcription factor WhiB BWK49_RS22745 7a9cd3ea58045d10db625ef193ebb75f 84 Pfam PF02467 Transcription factor WhiB 3 71 1.8E-26 T 06-07-2017 IPR003482 Transcription factor WhiB BWK49_RS27200 1010e554e2448cc1cb06df89d98bc7b1 241 Gene3D G3DSA:2.60.120.10 6 236 3.9E-62 T 06-07-2017 IPR014710 RmlC-like jelly roll fold BWK49_RS27200 1010e554e2448cc1cb06df89d98bc7b1 241 Pfam PF02678 Pirin 12 122 1.3E-37 T 06-07-2017 IPR003829 Pirin, N-terminal domain BWK49_RS27200 1010e554e2448cc1cb06df89d98bc7b1 241 PIRSF PIRSF006232 2 237 2.6E-52 T 06-07-2017 IPR012093 Pirin BWK49_RS27200 1010e554e2448cc1cb06df89d98bc7b1 241 SUPERFAMILY SSF51182 6 235 2.62E-63 T 06-07-2017 IPR011051 RmlC-like cupin domain BWK49_RS19650 1be7452fb48e6dd0f3dbbc2f3621c9b1 276 Gene3D G3DSA:3.40.50.720 5 273 2.0E-74 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS19650 1be7452fb48e6dd0f3dbbc2f3621c9b1 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 1.0E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS19650 1be7452fb48e6dd0f3dbbc2f3621c9b1 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 143 159 1.0E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS19650 1be7452fb48e6dd0f3dbbc2f3621c9b1 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 194 211 1.0E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS19650 1be7452fb48e6dd0f3dbbc2f3621c9b1 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 99 110 1.0E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS19650 1be7452fb48e6dd0f3dbbc2f3621c9b1 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 192 1.0E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS19650 1be7452fb48e6dd0f3dbbc2f3621c9b1 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 237 257 1.0E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS19650 1be7452fb48e6dd0f3dbbc2f3621c9b1 276 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 160 188 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS19650 1be7452fb48e6dd0f3dbbc2f3621c9b1 276 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 273 7.5E-44 T 06-07-2017 BWK49_RS19650 1be7452fb48e6dd0f3dbbc2f3621c9b1 276 TIGRFAM TIGR03971 SDR_subfam_1: SDR family mycofactocin-dependent oxidoreductase 9 275 6.5E-110 T 06-07-2017 IPR023985 Mycofactocin-dependent oxidoreductase BWK49_RS19650 1be7452fb48e6dd0f3dbbc2f3621c9b1 276 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 99 110 6.9E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS19650 1be7452fb48e6dd0f3dbbc2f3621c9b1 276 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 173 192 6.9E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS19650 1be7452fb48e6dd0f3dbbc2f3621c9b1 276 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 157 6.9E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS19650 1be7452fb48e6dd0f3dbbc2f3621c9b1 276 SUPERFAMILY SSF51735 7 274 6.91E-65 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS16780 e9582a02bf08168e080cc737ac28cecb 327 TIGRFAM TIGR02823 oxido_YhdH: putative quinone oxidoreductase, YhdH/YhfP family 4 325 1.8E-134 T 06-07-2017 IPR014188 Acrylyl-CoA reductase AcuI BWK49_RS16780 e9582a02bf08168e080cc737ac28cecb 327 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 88 8.7E-6 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 BWK49_RS16780 e9582a02bf08168e080cc737ac28cecb 327 Gene3D G3DSA:3.90.180.10 16 139 1.4E-10 T 06-07-2017 IPR011032 GroES-like BWK49_RS16780 e9582a02bf08168e080cc737ac28cecb 327 Gene3D G3DSA:3.40.50.720 140 292 2.4E-73 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS16780 e9582a02bf08168e080cc737ac28cecb 327 SUPERFAMILY SSF51735 119 284 1.84E-34 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS16780 e9582a02bf08168e080cc737ac28cecb 327 SUPERFAMILY SSF50129 3 146 1.98E-44 T 06-07-2017 IPR011032 GroES-like BWK49_RS16780 e9582a02bf08168e080cc737ac28cecb 327 Pfam PF00107 Zinc-binding dehydrogenase 159 271 2.7E-10 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 BWK49_RS16780 e9582a02bf08168e080cc737ac28cecb 327 SMART SM00829 9 323 9.9E-6 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 BWK49_RS11395 14dea064e671930d82870d5fe187397e 71 SMART SM00923 4 54 8.3E-32 T 06-07-2017 IPR005153 MbtH-like protein BWK49_RS11395 14dea064e671930d82870d5fe187397e 71 Pfam PF03621 MbtH-like protein 3 54 4.2E-28 T 06-07-2017 IPR005153 MbtH-like protein BWK49_RS11395 14dea064e671930d82870d5fe187397e 71 Gene3D G3DSA:3.90.820.10 12 69 1.1E-29 T 06-07-2017 BWK49_RS11395 14dea064e671930d82870d5fe187397e 71 SUPERFAMILY SSF160582 3 69 4.32E-30 T 06-07-2017 BWK49_RS20225 c2df99aadd672a62707a7755ac83a077 289 SUPERFAMILY SSF63380 8 132 4.38E-8 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 BWK49_RS20225 c2df99aadd672a62707a7755ac83a077 289 Gene3D G3DSA:2.40.30.10 8 126 6.6E-29 T 06-07-2017 BWK49_RS20225 c2df99aadd672a62707a7755ac83a077 289 Pfam PF04954 Siderophore-interacting protein 134 262 4.4E-36 T 06-07-2017 IPR007037 Siderophore-interacting protein BWK49_RS20225 c2df99aadd672a62707a7755ac83a077 289 Gene3D G3DSA:3.40.50.80 129 281 4.6E-51 T 06-07-2017 BWK49_RS20225 c2df99aadd672a62707a7755ac83a077 289 Pfam PF08021 Siderophore-interacting FAD-binding domain 10 127 7.5E-33 T 06-07-2017 IPR013113 FAD-binding 9, siderophore-interacting BWK49_RS27285 6c486885c3c8351a41f7c8506820d8ee 231 SMART SM00895 92 214 7.1E-4 T 06-07-2017 IPR011711 GntR, C-terminal BWK49_RS27285 6c486885c3c8351a41f7c8506820d8ee 231 SMART SM00345 24 82 9.2E-11 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 BWK49_RS27285 6c486885c3c8351a41f7c8506820d8ee 231 Pfam PF07729 FCD domain 92 204 7.5E-23 T 06-07-2017 IPR011711 GntR, C-terminal BWK49_RS27285 6c486885c3c8351a41f7c8506820d8ee 231 Pfam PF00392 Bacterial regulatory proteins, gntR family 20 82 1.8E-15 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 BWK49_RS27285 6c486885c3c8351a41f7c8506820d8ee 231 Gene3D G3DSA:1.10.10.10 5 82 1.6E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS27285 6c486885c3c8351a41f7c8506820d8ee 231 Gene3D G3DSA:1.20.120.530 85 222 2.1E-14 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal BWK49_RS27285 6c486885c3c8351a41f7c8506820d8ee 231 SUPERFAMILY SSF48008 88 221 9.42E-14 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal BWK49_RS27285 6c486885c3c8351a41f7c8506820d8ee 231 SUPERFAMILY SSF46785 15 99 4.89E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS22085 72020ab7f2fc055a17c98142c459d48d 462 Pfam PF02720 Domain of unknown function (DUF222) 44 370 6.7E-79 T 06-07-2017 IPR003870 Domain of unknown function DUF222 BWK49_RS10115 2100add1062967a0fe4a786529a59eaa 1002 Pfam PF03176 MMPL family 649 991 9.8E-90 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 BWK49_RS10115 2100add1062967a0fe4a786529a59eaa 1002 Pfam PF03176 MMPL family 44 371 4.8E-98 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 BWK49_RS10115 2100add1062967a0fe4a786529a59eaa 1002 Gene3D G3DSA:1.20.1640.10 770 983 7.8E-20 T 06-07-2017 BWK49_RS10115 2100add1062967a0fe4a786529a59eaa 1002 Gene3D G3DSA:1.20.1640.10 181 351 1.9E-24 T 06-07-2017 BWK49_RS10115 2100add1062967a0fe4a786529a59eaa 1002 TIGRFAM TIGR00833 actII: transport protein 10 981 2.3E-278 T 06-07-2017 IPR004707 Membrane transport protein MmpL family GO:0016021 BWK49_RS10115 2100add1062967a0fe4a786529a59eaa 1002 SUPERFAMILY SSF82866 154 346 3.4E-26 T 06-07-2017 BWK49_RS10115 2100add1062967a0fe4a786529a59eaa 1002 SUPERFAMILY SSF82866 766 981 5.89E-27 T 06-07-2017 BWK49_RS03585 2ae4855c7117b5bbaa241d5e5a49d2a6 63 Gene3D G3DSA:3.30.70.20 2 60 2.9E-17 T 06-07-2017 BWK49_RS03585 2ae4855c7117b5bbaa241d5e5a49d2a6 63 PRINTS PR00352 3Fe-4S ferredoxin signature 5 16 7.7E-5 T 06-07-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 BWK49_RS03585 2ae4855c7117b5bbaa241d5e5a49d2a6 63 PRINTS PR00352 3Fe-4S ferredoxin signature 47 59 7.7E-5 T 06-07-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 BWK49_RS03585 2ae4855c7117b5bbaa241d5e5a49d2a6 63 PRINTS PR00352 3Fe-4S ferredoxin signature 16 26 7.7E-5 T 06-07-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 BWK49_RS03585 2ae4855c7117b5bbaa241d5e5a49d2a6 63 Pfam PF13459 4Fe-4S single cluster domain 3 59 2.0E-14 T 06-07-2017 BWK49_RS03585 2ae4855c7117b5bbaa241d5e5a49d2a6 63 SUPERFAMILY SSF54862 2 60 5.16E-10 T 06-07-2017 BWK49_RS08285 a4150a9242bc97e50be69211ad3a43b0 304 Gene3D G3DSA:3.40.50.10320 1 301 6.5E-91 T 06-07-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 BWK49_RS08285 a4150a9242bc97e50be69211ad3a43b0 304 Pfam PF02585 GlcNAc-PI de-N-acetylase 8 157 7.8E-27 T 06-07-2017 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 BWK49_RS08285 a4150a9242bc97e50be69211ad3a43b0 304 Hamap MF_01696 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase [mshB]. 7 296 40.575 T 06-07-2017 IPR017810 Mycothiol biosynthesis protein, MshB GO:0035595 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 BWK49_RS08285 a4150a9242bc97e50be69211ad3a43b0 304 SUPERFAMILY SSF102588 4 297 1.96E-80 T 06-07-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 BWK49_RS08285 a4150a9242bc97e50be69211ad3a43b0 304 TIGRFAM TIGR03445 mycothiol_MshB: N-acetyl-1-D-myo-inositol-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase 8 296 6.0E-140 T 06-07-2017 IPR017810 Mycothiol biosynthesis protein, MshB GO:0035595 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 BWK49_RS01915 84df211ea4e2fd8215336535704c277c 402 SUPERFAMILY SSF53098 287 402 4.55E-7 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS01915 84df211ea4e2fd8215336535704c277c 402 Pfam PF13936 Helix-turn-helix domain 76 119 1.0E-18 T 06-07-2017 IPR025246 Transposase IS30-like HTH domain BWK49_RS01665 84df211ea4e2fd8215336535704c277c 402 SUPERFAMILY SSF53098 287 402 4.55E-7 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS01665 84df211ea4e2fd8215336535704c277c 402 Pfam PF13936 Helix-turn-helix domain 76 119 1.0E-18 T 06-07-2017 IPR025246 Transposase IS30-like HTH domain BWK49_RS04965 095ea7c4ef617476acd0a65926566461 338 SUPERFAMILY SSF47240 32 256 8.49E-8 T 06-07-2017 IPR009078 Ferritin-like superfamily BWK49_RS04965 095ea7c4ef617476acd0a65926566461 338 Pfam PF11583 P-aminobenzoate N-oxygenase AurF 19 303 9.0E-107 T 06-07-2017 IPR025859 P-aminobenzoate N-oxygenase AurF BWK49_RS09205 78f430d169d9be21635f1aa2c323d87a 405 SUPERFAMILY SSF53901 277 401 5.46E-42 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS09205 78f430d169d9be21635f1aa2c323d87a 405 Pfam PF02803 Thiolase, C-terminal domain 276 401 1.3E-42 T 06-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 BWK49_RS09205 78f430d169d9be21635f1aa2c323d87a 405 PIRSF PIRSF000429 1 403 1.8E-129 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 BWK49_RS09205 78f430d169d9be21635f1aa2c323d87a 405 SUPERFAMILY SSF53901 4 276 3.38E-78 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS09205 78f430d169d9be21635f1aa2c323d87a 405 Gene3D G3DSA:3.40.47.10 198 281 1.3E-59 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS09205 78f430d169d9be21635f1aa2c323d87a 405 Gene3D G3DSA:3.40.47.10 5 123 1.3E-59 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS09205 78f430d169d9be21635f1aa2c323d87a 405 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 400 2.9E-132 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 BWK49_RS09205 78f430d169d9be21635f1aa2c323d87a 405 Pfam PF00108 Thiolase, N-terminal domain 5 267 4.2E-68 T 06-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 BWK49_RS09205 78f430d169d9be21635f1aa2c323d87a 405 Gene3D G3DSA:3.40.47.10 283 401 1.2E-59 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS09205 78f430d169d9be21635f1aa2c323d87a 405 Gene3D G3DSA:3.40.47.10 160 197 1.2E-59 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS27195 545b3f3275e9db5b41fff90906a9f489 292 Gene3D G3DSA:3.30.450.40 246 290 1.5E-11 T 06-07-2017 IPR029016 GAF domain-like BWK49_RS27195 545b3f3275e9db5b41fff90906a9f489 292 Gene3D G3DSA:3.30.450.40 84 200 1.5E-11 T 06-07-2017 IPR029016 GAF domain-like BWK49_RS27195 545b3f3275e9db5b41fff90906a9f489 292 SUPERFAMILY SSF46785 16 82 6.75E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS27195 545b3f3275e9db5b41fff90906a9f489 292 Pfam PF12802 MarR family 18 68 3.3E-7 T 06-07-2017 BWK49_RS27195 545b3f3275e9db5b41fff90906a9f489 292 SUPERFAMILY SSF55781 69 189 1.24E-7 T 06-07-2017 IPR029016 GAF domain-like BWK49_RS27195 545b3f3275e9db5b41fff90906a9f489 292 Gene3D G3DSA:1.10.10.10 13 83 3.3E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS28325 7d88ebd3f5cbefc94842a2ce293dc5d3 195 Gene3D G3DSA:1.10.1740.10 10 116 1.3E-29 T 06-07-2017 BWK49_RS28325 7d88ebd3f5cbefc94842a2ce293dc5d3 195 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 27 176 6.0E-21 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS28325 7d88ebd3f5cbefc94842a2ce293dc5d3 195 SUPERFAMILY SSF88659 114 177 2.4E-13 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS28325 7d88ebd3f5cbefc94842a2ce293dc5d3 195 Pfam PF08281 Sigma-70, region 4 121 173 1.1E-13 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS28325 7d88ebd3f5cbefc94842a2ce293dc5d3 195 Gene3D G3DSA:1.10.10.10 118 178 4.5E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS28325 7d88ebd3f5cbefc94842a2ce293dc5d3 195 Pfam PF04542 Sigma-70 region 2 31 97 9.2E-16 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS28325 7d88ebd3f5cbefc94842a2ce293dc5d3 195 SUPERFAMILY SSF88946 10 111 5.18E-28 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS15955 e806ba4d271c661decfa653e6778d539 601 Pfam PF00733 Asparagine synthase 246 592 3.8E-84 T 06-07-2017 IPR001962 Asparagine synthase GO:0004066|GO:0006529 BWK49_RS15955 e806ba4d271c661decfa653e6778d539 601 TIGRFAM TIGR03104 trio_amidotrans: asparagine synthase family amidotransferase 1 594 0.0 T 06-07-2017 IPR017535 Asparagine synthase family amidotransferase BWK49_RS15955 e806ba4d271c661decfa653e6778d539 601 PIRSF PIRSF001589 1 601 1.8E-205 T 06-07-2017 BWK49_RS15955 e806ba4d271c661decfa653e6778d539 601 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 525 1.4E-125 T 06-07-2017 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 BWK49_RS15955 e806ba4d271c661decfa653e6778d539 601 Gene3D G3DSA:3.40.50.620 442 592 1.9E-81 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold BWK49_RS15955 e806ba4d271c661decfa653e6778d539 601 Gene3D G3DSA:3.40.50.620 225 384 1.9E-81 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold BWK49_RS15955 e806ba4d271c661decfa653e6778d539 601 Gene3D G3DSA:3.60.20.10 2 224 1.6E-66 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal BWK49_RS15955 e806ba4d271c661decfa653e6778d539 601 SUPERFAMILY SSF56235 2 224 1.03E-58 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal BWK49_RS15955 e806ba4d271c661decfa653e6778d539 601 Pfam PF13537 Glutamine amidotransferase domain 47 167 1.5E-41 T 06-07-2017 IPR017932 Glutamine amidotransferase type 2 domain BWK49_RS15955 e806ba4d271c661decfa653e6778d539 601 SUPERFAMILY SSF52402 233 388 6.02E-77 T 06-07-2017 BWK49_RS15955 e806ba4d271c661decfa653e6778d539 601 SUPERFAMILY SSF52402 447 571 6.02E-77 T 06-07-2017 BWK49_RS17910 38197f74827d2f97a705ebfb0da04194 967 SUPERFAMILY SSF52016 691 960 2.75E-81 T 06-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel BWK49_RS17910 38197f74827d2f97a705ebfb0da04194 967 SUPERFAMILY SSF53732 22 421 6.67E-223 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 BWK49_RS17910 38197f74827d2f97a705ebfb0da04194 967 SUPERFAMILY SSF53732 461 687 6.67E-223 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 BWK49_RS17910 38197f74827d2f97a705ebfb0da04194 967 Pfam PF00694 Aconitase C-terminal domain 751 885 8.3E-42 T 06-07-2017 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 BWK49_RS17910 38197f74827d2f97a705ebfb0da04194 967 PRINTS PR00415 Aconitase family signature 160 173 5.9E-41 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 BWK49_RS17910 38197f74827d2f97a705ebfb0da04194 967 PRINTS PR00415 Aconitase family signature 184 192 5.9E-41 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 BWK49_RS17910 38197f74827d2f97a705ebfb0da04194 967 PRINTS PR00415 Aconitase family signature 553 566 5.9E-41 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 BWK49_RS17910 38197f74827d2f97a705ebfb0da04194 967 PRINTS PR00415 Aconitase family signature 294 307 5.9E-41 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 BWK49_RS17910 38197f74827d2f97a705ebfb0da04194 967 PRINTS PR00415 Aconitase family signature 232 247 5.9E-41 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 BWK49_RS17910 38197f74827d2f97a705ebfb0da04194 967 PRINTS PR00415 Aconitase family signature 308 321 5.9E-41 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 BWK49_RS17910 38197f74827d2f97a705ebfb0da04194 967 PRINTS PR00415 Aconitase family signature 387 401 5.9E-41 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 BWK49_RS17910 38197f74827d2f97a705ebfb0da04194 967 PRINTS PR00415 Aconitase family signature 491 502 5.9E-41 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 BWK49_RS17910 38197f74827d2f97a705ebfb0da04194 967 PRINTS PR00415 Aconitase family signature 218 231 5.9E-41 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 BWK49_RS17910 38197f74827d2f97a705ebfb0da04194 967 ProSitePatterns PS00450 Aconitase family signature 1. 487 503 - T 06-07-2017 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 BWK49_RS17910 38197f74827d2f97a705ebfb0da04194 967 Gene3D G3DSA:3.30.499.10 383 408 1.7E-64 T 06-07-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 BWK49_RS17910 38197f74827d2f97a705ebfb0da04194 967 Gene3D G3DSA:3.30.499.10 479 635 1.7E-64 T 06-07-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 BWK49_RS17910 38197f74827d2f97a705ebfb0da04194 967 ProSitePatterns PS01244 Aconitase family signature 2. 553 566 - T 06-07-2017 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 BWK49_RS17910 38197f74827d2f97a705ebfb0da04194 967 Gene3D G3DSA:3.20.19.10 697 960 1.3E-74 T 06-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel BWK49_RS17910 38197f74827d2f97a705ebfb0da04194 967 Pfam PF00330 Aconitase family (aconitate hydratase) 83 622 1.1E-176 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 BWK49_RS17910 38197f74827d2f97a705ebfb0da04194 967 Gene3D G3DSA:3.30.499.10 46 264 3.3E-79 T 06-07-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 BWK49_RS17910 38197f74827d2f97a705ebfb0da04194 967 Gene3D G3DSA:3.40.1060.10 265 382 2.9E-36 T 06-07-2017 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 BWK49_RS14895 78090648599c03c0fef0238175d918f1 494 Gene3D G3DSA:3.40.47.10 285 384 1.2E-4 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS14895 78090648599c03c0fef0238175d918f1 494 SUPERFAMILY SSF53901 233 260 1.19E-5 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS14895 78090648599c03c0fef0238175d918f1 494 SUPERFAMILY SSF53901 27 123 1.19E-5 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS14895 78090648599c03c0fef0238175d918f1 494 SUPERFAMILY SSF53901 284 395 3.5E-19 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS03220 ddb7b1df3ba8b6b99725ac10f1effc70 286 Gene3D G3DSA:1.10.3470.10 57 282 2.7E-5 T 06-07-2017 IPR029022 ABC transporter, BtuC-like BWK49_RS03220 ddb7b1df3ba8b6b99725ac10f1effc70 286 Pfam PF00950 ABC 3 transport family 24 277 2.1E-42 T 06-07-2017 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 BWK49_RS03220 ddb7b1df3ba8b6b99725ac10f1effc70 286 SUPERFAMILY SSF81345 15 275 6.54E-33 T 06-07-2017 IPR029022 ABC transporter, BtuC-like BWK49_RS08490 26567c14f6f60989ceec2d0de992c12f 390 TIGRFAM TIGR02149 glgA_Coryne: glycogen synthase, Corynebacterium family 1 389 6.0E-190 T 06-07-2017 IPR011875 Glycogen synthase, corynebacterial KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 BWK49_RS08490 26567c14f6f60989ceec2d0de992c12f 390 SUPERFAMILY SSF53756 1 388 1.7E-87 T 06-07-2017 BWK49_RS08490 26567c14f6f60989ceec2d0de992c12f 390 Pfam PF00534 Glycosyl transferases group 1 196 367 1.2E-28 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 BWK49_RS08490 26567c14f6f60989ceec2d0de992c12f 390 Pfam PF13439 Glycosyltransferase Family 4 15 179 2.5E-31 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 BWK49_RS08490 26567c14f6f60989ceec2d0de992c12f 390 Gene3D G3DSA:3.40.50.2000 165 367 7.5E-47 T 06-07-2017 BWK49_RS06910 3050e1047bdf35c331d33ee68954d7ae 268 SUPERFAMILY SSF52096 5 267 4.2E-72 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS06910 3050e1047bdf35c331d33ee68954d7ae 268 Gene3D G3DSA:3.90.226.10 2 265 4.0E-70 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS06910 3050e1047bdf35c331d33ee68954d7ae 268 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 266 1.8E-49 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 BWK49_RS06910 3050e1047bdf35c331d33ee68954d7ae 268 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 107 127 - T 06-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 BWK49_RS08460 ecf7ddeb0d94472cf5cb1b956cc037e5 592 Gene3D G3DSA:3.40.50.980 207 350 9.0E-23 T 06-07-2017 BWK49_RS08460 ecf7ddeb0d94472cf5cb1b956cc037e5 592 ProSitePatterns PS00455 Putative AMP-binding domain signature. 201 212 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS08460 ecf7ddeb0d94472cf5cb1b956cc037e5 592 Pfam PF00501 AMP-binding enzyme 53 461 6.3E-67 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS08460 ecf7ddeb0d94472cf5cb1b956cc037e5 592 Gene3D G3DSA:2.30.38.10 389 442 5.1E-6 T 06-07-2017 BWK49_RS08460 ecf7ddeb0d94472cf5cb1b956cc037e5 592 Pfam PF13193 AMP-binding enzyme C-terminal domain 471 546 7.1E-11 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS08460 ecf7ddeb0d94472cf5cb1b956cc037e5 592 Gene3D G3DSA:3.40.50.980 47 206 2.3E-37 T 06-07-2017 BWK49_RS08460 ecf7ddeb0d94472cf5cb1b956cc037e5 592 SUPERFAMILY SSF56801 45 558 1.23E-104 T 06-07-2017 BWK49_RS08460 ecf7ddeb0d94472cf5cb1b956cc037e5 592 Gene3D G3DSA:3.30.300.30 462 558 3.5E-14 T 06-07-2017 BWK49_RS04390 b6c0c7e362c83541a139477ef960d073 138 Pfam PF01381 Helix-turn-helix 15 44 9.8E-6 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 BWK49_RS04390 b6c0c7e362c83541a139477ef960d073 138 Gene3D G3DSA:1.10.260.40 14 63 8.7E-7 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 BWK49_RS04390 b6c0c7e362c83541a139477ef960d073 138 SUPERFAMILY SSF47413 8 67 1.06E-7 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 BWK49_RS26175 6f5a6312a0be74adf217f2808ff9f7ee 434 Gene3D G3DSA:3.90.1150.10 310 433 1.3E-37 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 BWK49_RS26175 6f5a6312a0be74adf217f2808ff9f7ee 434 SUPERFAMILY SSF53383 33 429 2.29E-93 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase BWK49_RS26175 6f5a6312a0be74adf217f2808ff9f7ee 434 Pfam PF00155 Aminotransferase class I and II 65 411 4.2E-47 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 BWK49_RS26175 6f5a6312a0be74adf217f2808ff9f7ee 434 Gene3D G3DSA:3.40.640.10 80 309 7.3E-66 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 BWK49_RS13430 94d34b50e343712ee280f796f4f41df5 335 Pfam PF13280 WYL domain 154 329 3.6E-28 T 06-07-2017 IPR026881 WYL domain BWK49_RS16985 8509af18c8e623e596d4a521c67d13c2 347 SUPERFAMILY SSF46589 23 107 1.1E-14 T 06-07-2017 IPR010978 tRNA-binding arm GO:0000166 BWK49_RS16985 8509af18c8e623e596d4a521c67d13c2 347 SUPERFAMILY SSF55681 101 339 2.41E-74 T 06-07-2017 BWK49_RS16985 8509af18c8e623e596d4a521c67d13c2 347 Pfam PF01409 tRNA synthetases class II core domain (F) 101 340 6.6E-99 T 06-07-2017 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 BWK49_RS16985 8509af18c8e623e596d4a521c67d13c2 347 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 17 343 44.539 T 06-07-2017 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 BWK49_RS16985 8509af18c8e623e596d4a521c67d13c2 347 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 52 339 4.7E-84 T 06-07-2017 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 BWK49_RS16985 8509af18c8e623e596d4a521c67d13c2 347 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 28 96 1.2E-15 T 06-07-2017 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 BWK49_RS16985 8509af18c8e623e596d4a521c67d13c2 347 Gene3D G3DSA:3.30.930.10 19 343 1.5E-116 T 06-07-2017 BWK49_RS13750 281e28b5b113b820bc7e50884b534963 266 Gene3D G3DSA:3.10.450.50 4 134 8.8E-33 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS13750 281e28b5b113b820bc7e50884b534963 266 Pfam PF02136 Nuclear transport factor 2 (NTF2) domain 12 92 6.4E-9 T 06-07-2017 IPR002075 Nuclear transport factor 2 GO:0005622|GO:0006810 BWK49_RS13750 281e28b5b113b820bc7e50884b534963 266 SUPERFAMILY SSF54427 5 131 9.41E-18 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS24345 bca255aba6de54eccd1a5cfc2536d0cc 481 TIGRFAM TIGR03970 Rv0697: dehydrogenase, Rv0697 family 8 478 2.0E-204 T 06-07-2017 IPR023978 Glucose-methanol-choline oxidoreductase, actinobacteria BWK49_RS24345 bca255aba6de54eccd1a5cfc2536d0cc 481 Pfam PF00732 GMC oxidoreductase 9 298 8.9E-50 T 06-07-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 BWK49_RS24345 bca255aba6de54eccd1a5cfc2536d0cc 481 SUPERFAMILY SSF54373 318 405 5.1E-13 T 06-07-2017 BWK49_RS24345 bca255aba6de54eccd1a5cfc2536d0cc 481 Gene3D G3DSA:3.50.50.60 7 128 6.2E-77 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS24345 bca255aba6de54eccd1a5cfc2536d0cc 481 Gene3D G3DSA:3.50.50.60 192 318 6.2E-77 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS24345 bca255aba6de54eccd1a5cfc2536d0cc 481 Gene3D G3DSA:3.50.50.60 415 478 6.2E-77 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS24345 bca255aba6de54eccd1a5cfc2536d0cc 481 Pfam PF05199 GMC oxidoreductase 358 474 1.2E-29 T 06-07-2017 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 BWK49_RS24345 bca255aba6de54eccd1a5cfc2536d0cc 481 SUPERFAMILY SSF51905 418 478 2.05E-58 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS24345 bca255aba6de54eccd1a5cfc2536d0cc 481 SUPERFAMILY SSF51905 7 287 2.05E-58 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS19900 41654effb30f7ac8d62c6d2924965c52 444 Pfam PF01554 MatE 20 184 5.7E-23 T 06-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 BWK49_RS19900 41654effb30f7ac8d62c6d2924965c52 444 Pfam PF01554 MatE 247 398 3.2E-16 T 06-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 BWK49_RS19900 41654effb30f7ac8d62c6d2924965c52 444 TIGRFAM TIGR00797 matE: MATE efflux family protein 20 415 1.9E-92 T 06-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 BWK49_RS08885 42566d01d06310b883f652350434e6c4 441 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 185 207 - T 06-07-2017 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 BWK49_RS08885 42566d01d06310b883f652350434e6c4 441 PIRSF PIRSF000098 5 439 3.3E-153 T 06-07-2017 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 BWK49_RS08885 42566d01d06310b883f652350434e6c4 441 Gene3D G3DSA:3.30.360.10 151 306 1.5E-54 T 06-07-2017 BWK49_RS08885 42566d01d06310b883f652350434e6c4 441 SUPERFAMILY SSF55347 139 309 4.05E-51 T 06-07-2017 BWK49_RS08885 42566d01d06310b883f652350434e6c4 441 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 14 131 1.0E-20 T 06-07-2017 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 BWK49_RS08885 42566d01d06310b883f652350434e6c4 441 Pfam PF00742 Homoserine dehydrogenase 139 322 8.3E-67 T 06-07-2017 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 BWK49_RS08885 42566d01d06310b883f652350434e6c4 441 SUPERFAMILY SSF55021 353 431 1.5E-10 T 06-07-2017 BWK49_RS08885 42566d01d06310b883f652350434e6c4 441 Gene3D G3DSA:3.40.50.720 4 150 2.4E-44 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS08885 42566d01d06310b883f652350434e6c4 441 SUPERFAMILY SSF51735 6 160 1.22E-31 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS08885 42566d01d06310b883f652350434e6c4 441 Pfam PF01842 ACT domain 355 424 3.9E-9 T 06-07-2017 IPR002912 ACT domain GO:0008152|GO:0016597 BWK49_RS08885 42566d01d06310b883f652350434e6c4 441 Gene3D G3DSA:3.30.70.260 354 430 1.2E-5 T 06-07-2017 BWK49_RS04060 1f548fa25b89366eceaba20eae14e211 532 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 41 493 8.3E-163 T 06-07-2017 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 BWK49_RS04060 1f548fa25b89366eceaba20eae14e211 532 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 40 494 46.572 T 06-07-2017 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 BWK49_RS04060 1f548fa25b89366eceaba20eae14e211 532 PIRSF PIRSF000485 37 508 4.6E-158 T 06-07-2017 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 BWK49_RS04060 1f548fa25b89366eceaba20eae14e211 532 Pfam PF00156 Phosphoribosyl transferase domain 317 417 2.2E-7 T 06-07-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 BWK49_RS04060 1f548fa25b89366eceaba20eae14e211 532 SUPERFAMILY SSF53271 282 501 2.62E-65 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like BWK49_RS04060 1f548fa25b89366eceaba20eae14e211 532 Gene3D G3DSA:3.40.50.2020 304 474 6.1E-43 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like BWK49_RS04060 1f548fa25b89366eceaba20eae14e211 532 Pfam PF13522 Glutamine amidotransferase domain 99 241 7.2E-15 T 06-07-2017 BWK49_RS04060 1f548fa25b89366eceaba20eae14e211 532 Gene3D G3DSA:3.60.20.10 41 288 3.3E-62 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal BWK49_RS04060 1f548fa25b89366eceaba20eae14e211 532 SUPERFAMILY SSF56235 41 299 2.49E-63 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal BWK49_RS00360 013e827bba9e7c7408464a48073fccf4 842 Gene3D G3DSA:3.40.710.10 368 778 7.8E-96 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like BWK49_RS00360 013e827bba9e7c7408464a48073fccf4 842 Gene3D G3DSA:1.10.3810.10 197 367 1.4E-60 T 06-07-2017 BWK49_RS00360 013e827bba9e7c7408464a48073fccf4 842 Pfam PF00905 Penicillin binding protein transpeptidase domain 461 719 8.9E-27 T 06-07-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 BWK49_RS00360 013e827bba9e7c7408464a48073fccf4 842 SUPERFAMILY SSF56601 349 371 5.07E-90 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like BWK49_RS00360 013e827bba9e7c7408464a48073fccf4 842 SUPERFAMILY SSF56601 403 768 5.07E-90 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like BWK49_RS00360 013e827bba9e7c7408464a48073fccf4 842 SUPERFAMILY SSF53955 175 382 9.28E-64 T 06-07-2017 IPR023346 Lysozyme-like domain BWK49_RS00360 013e827bba9e7c7408464a48073fccf4 842 Pfam PF00912 Transglycosylase 189 367 1.7E-56 T 06-07-2017 IPR001264 Glycosyl transferase, family 51 BWK49_RS15380 4f9bfa8ad7e22c2f046d3c7711981115 332 Pfam PF02780 Transketolase, C-terminal domain 195 317 5.9E-35 T 06-07-2017 IPR033248 Transketolase, C-terminal domain BWK49_RS15380 4f9bfa8ad7e22c2f046d3c7711981115 332 Gene3D G3DSA:3.40.50.920 196 325 1.4E-38 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 BWK49_RS15380 4f9bfa8ad7e22c2f046d3c7711981115 332 SMART SM00861 6 179 4.4E-53 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain BWK49_RS15380 4f9bfa8ad7e22c2f046d3c7711981115 332 Pfam PF02779 Transketolase, pyrimidine binding domain 5 174 1.6E-40 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain BWK49_RS15380 4f9bfa8ad7e22c2f046d3c7711981115 332 SUPERFAMILY SSF52922 190 325 1.2E-35 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 BWK49_RS15380 4f9bfa8ad7e22c2f046d3c7711981115 332 Gene3D G3DSA:3.40.50.970 4 195 1.1E-73 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS15380 4f9bfa8ad7e22c2f046d3c7711981115 332 SUPERFAMILY SSF52518 3 205 8.34E-59 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS13490 7050ceac17d28066e0ddb9f9bd742580 388 Gene3D G3DSA:3.30.950.10 104 200 4.0E-18 T 06-07-2017 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 BWK49_RS13490 7050ceac17d28066e0ddb9f9bd742580 388 TIGRFAM TIGR02469 CbiT: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit 221 340 9.0E-26 T 06-07-2017 IPR014008 Cobalamin biosynthesis, precorrin-6Y methyltransferase, CbiT subunit GO:0008276|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.196|MetaCyc: PWY-2201|MetaCyc: PWY-7377 BWK49_RS13490 7050ceac17d28066e0ddb9f9bd742580 388 TIGRFAM TIGR02467 CbiE: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit 4 186 4.0E-38 T 06-07-2017 IPR012818 Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase GO:0008276|GO:0009236 BWK49_RS13490 7050ceac17d28066e0ddb9f9bd742580 388 PIRSF PIRSF036428 1 388 2.7E-126 T 06-07-2017 IPR006365 Cobalamin (vitamin B12) biosynthesis CobL/Precorrin-6Y C(5,15)-methyltransferase GO:0008276|GO:0009236 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|KEGG: 00860+2.1.1.132|MetaCyc: PWY-2201|MetaCyc: PWY-3841 BWK49_RS13490 7050ceac17d28066e0ddb9f9bd742580 388 SUPERFAMILY SSF53335 199 356 9.81E-23 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS13490 7050ceac17d28066e0ddb9f9bd742580 388 Gene3D G3DSA:3.40.50.150 214 357 8.5E-16 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS13490 7050ceac17d28066e0ddb9f9bd742580 388 SUPERFAMILY SSF53790 2 200 1.22E-33 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 BWK49_RS13490 7050ceac17d28066e0ddb9f9bd742580 388 Gene3D G3DSA:3.40.1010.10 2 103 8.0E-23 T 06-07-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 BWK49_RS13490 7050ceac17d28066e0ddb9f9bd742580 388 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 2 182 2.3E-18 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 BWK49_RS26810 d391621202279d5666b6d422a5a9a6e9 771 Gene3D G3DSA:2.40.40.20 650 766 8.7E-8 T 06-07-2017 BWK49_RS26810 d391621202279d5666b6d422a5a9a6e9 771 Pfam PF01568 Molydopterin dinucleotide binding domain 654 760 1.1E-7 T 06-07-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 BWK49_RS26810 d391621202279d5666b6d422a5a9a6e9 771 SUPERFAMILY SSF50692 647 766 9.49E-13 T 06-07-2017 IPR009010 Aspartate decarboxylase-like domain BWK49_RS26810 d391621202279d5666b6d422a5a9a6e9 771 PIRSF PIRSF000144 17 771 3.1E-303 T 06-07-2017 IPR010046 Oxidoreductase alpha (molybdopterin) subunit GO:0008863|GO:0030151|GO:0051539 BWK49_RS26810 d391621202279d5666b6d422a5a9a6e9 771 TIGRFAM TIGR01701 Fdhalpha-like: oxidoreductase alpha (molybdopterin) subunit 31 766 1.1E-254 T 06-07-2017 IPR010046 Oxidoreductase alpha (molybdopterin) subunit GO:0008863|GO:0030151|GO:0051539 BWK49_RS26810 d391621202279d5666b6d422a5a9a6e9 771 Pfam PF00384 Molybdopterin oxidoreductase 128 502 5.1E-23 T 06-07-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS26810 d391621202279d5666b6d422a5a9a6e9 771 Gene3D G3DSA:3.40.228.10 202 408 9.2E-51 T 06-07-2017 BWK49_RS26810 d391621202279d5666b6d422a5a9a6e9 771 Gene3D G3DSA:3.40.50.740 128 201 1.9E-51 T 06-07-2017 BWK49_RS26810 d391621202279d5666b6d422a5a9a6e9 771 Gene3D G3DSA:3.40.50.740 409 640 1.9E-51 T 06-07-2017 BWK49_RS26810 d391621202279d5666b6d422a5a9a6e9 771 SUPERFAMILY SSF53706 66 645 3.27E-132 T 06-07-2017 BWK49_RS23575 3099c8790196067d18b672bc151acba2 195 SUPERFAMILY SSF52540 19 175 3.48E-21 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS23575 3099c8790196067d18b672bc151acba2 195 Gene3D G3DSA:3.40.50.300 9 187 1.7E-13 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS23575 3099c8790196067d18b672bc151acba2 195 Pfam PF03029 Conserved hypothetical ATP binding protein 22 189 4.3E-28 T 06-07-2017 IPR004130 GPN-loop GTPase BWK49_RS24375 cd57aeaa91904a4a690242e856269dae 49 TIGRFAM TIGR03969 mycofactocin: mycofactocin precursor 28 49 1.5E-14 T 06-07-2017 IPR023988 Mycofactocin BWK49_RS17535 aacec29118cb411fd59f761a2b97accf 143 SUPERFAMILY SSF55961 4 142 5.9E-22 T 06-07-2017 BWK49_RS17535 aacec29118cb411fd59f761a2b97accf 143 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 3 141 5.4E-25 T 06-07-2017 IPR019587 Polyketide cyclase/dehydrase BWK49_RS17535 aacec29118cb411fd59f761a2b97accf 143 Gene3D G3DSA:3.30.530.20 4 139 6.9E-17 T 06-07-2017 IPR023393 START-like domain BWK49_RS02435 f3633e409d6a02a322a933ef8292ab2f 425 Gene3D G3DSA:3.40.710.10 18 379 2.4E-64 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like BWK49_RS02435 f3633e409d6a02a322a933ef8292ab2f 425 Pfam PF00144 Beta-lactamase 38 374 3.2E-57 T 06-07-2017 IPR001466 Beta-lactamase-related BWK49_RS02435 f3633e409d6a02a322a933ef8292ab2f 425 SUPERFAMILY SSF56601 22 231 2.3E-58 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like BWK49_RS02435 f3633e409d6a02a322a933ef8292ab2f 425 SUPERFAMILY SSF56601 268 374 2.3E-58 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like BWK49_RS14450 d73b746481ac719755b091c88153382a 136 Gene3D G3DSA:3.10.180.10 1 132 1.3E-28 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS14450 d73b746481ac719755b091c88153382a 136 SUPERFAMILY SSF54593 1 134 2.28E-26 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS14450 d73b746481ac719755b091c88153382a 136 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 132 4.2E-16 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain BWK49_RS03230 c44c2a710e8162f1bbe3d1d7f1cb3827 300 Gene3D G3DSA:3.40.50.1980 184 293 3.8E-10 T 06-07-2017 BWK49_RS03230 c44c2a710e8162f1bbe3d1d7f1cb3827 300 Pfam PF01297 Zinc-uptake complex component A periplasmic 34 288 5.6E-45 T 06-07-2017 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 BWK49_RS03230 c44c2a710e8162f1bbe3d1d7f1cb3827 300 SUPERFAMILY SSF53807 32 293 8.34E-56 T 06-07-2017 BWK49_RS03230 c44c2a710e8162f1bbe3d1d7f1cb3827 300 Gene3D G3DSA:3.40.50.1980 21 164 1.5E-32 T 06-07-2017 BWK49_RS03110 2c0b56ccd07ae9ac3661266519d2601c 498 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 14 497 36.567 T 06-07-2017 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 BWK49_RS03110 2c0b56ccd07ae9ac3661266519d2601c 498 Pfam PF00152 tRNA synthetases class II (D, K and N) 154 493 4.8E-68 T 06-07-2017 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 BWK49_RS03110 2c0b56ccd07ae9ac3661266519d2601c 498 SUPERFAMILY SSF55681 154 495 5.9E-97 T 06-07-2017 BWK49_RS03110 2c0b56ccd07ae9ac3661266519d2601c 498 PRINTS PR00982 Lysyl-tRNA synthetase signature 236 249 1.5E-34 T 06-07-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 BWK49_RS03110 2c0b56ccd07ae9ac3661266519d2601c 498 PRINTS PR00982 Lysyl-tRNA synthetase signature 191 201 1.5E-34 T 06-07-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 BWK49_RS03110 2c0b56ccd07ae9ac3661266519d2601c 498 PRINTS PR00982 Lysyl-tRNA synthetase signature 380 396 1.5E-34 T 06-07-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 BWK49_RS03110 2c0b56ccd07ae9ac3661266519d2601c 498 PRINTS PR00982 Lysyl-tRNA synthetase signature 207 223 1.5E-34 T 06-07-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 BWK49_RS03110 2c0b56ccd07ae9ac3661266519d2601c 498 PRINTS PR00982 Lysyl-tRNA synthetase signature 254 271 1.5E-34 T 06-07-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 BWK49_RS03110 2c0b56ccd07ae9ac3661266519d2601c 498 SUPERFAMILY SSF50249 7 147 5.14E-35 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS03110 2c0b56ccd07ae9ac3661266519d2601c 498 Gene3D G3DSA:3.30.930.10 150 492 3.3E-100 T 06-07-2017 BWK49_RS03110 2c0b56ccd07ae9ac3661266519d2601c 498 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 10 497 5.4E-144 T 06-07-2017 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 BWK49_RS03110 2c0b56ccd07ae9ac3661266519d2601c 498 Gene3D G3DSA:2.40.50.140 9 147 2.5E-45 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS03110 2c0b56ccd07ae9ac3661266519d2601c 498 Pfam PF01336 OB-fold nucleic acid binding domain 62 137 9.1E-11 T 06-07-2017 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 BWK49_RS02970 c16c8ee23145e1cb429c2802c9ba4435 232 Gene3D G3DSA:3.90.550.10 11 125 2.1E-15 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases BWK49_RS02970 c16c8ee23145e1cb429c2802c9ba4435 232 Pfam PF00535 Glycosyl transferase family 2 12 136 2.9E-26 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 BWK49_RS02970 c16c8ee23145e1cb429c2802c9ba4435 232 SUPERFAMILY SSF53448 10 214 8.44E-33 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases BWK49_RS06915 a9ab092ddb572c92fcd7330ca37be087 288 Gene3D G3DSA:3.20.20.30 10 231 2.6E-57 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS06915 a9ab092ddb572c92fcd7330ca37be087 288 Pfam PF00296 Luciferase-like monooxygenase 9 227 5.3E-44 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS06915 a9ab092ddb572c92fcd7330ca37be087 288 SUPERFAMILY SSF51679 7 285 7.2E-51 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS19810 a0f3763a64d1a13b28c1f1d468dfe73e 439 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 47 70 - T 06-07-2017 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 BWK49_RS19810 a0f3763a64d1a13b28c1f1d468dfe73e 439 Gene3D G3DSA:3.30.830.10 249 424 1.1E-46 T 06-07-2017 IPR011237 Peptidase M16 domain GO:0046872 BWK49_RS19810 a0f3763a64d1a13b28c1f1d468dfe73e 439 Pfam PF05193 Peptidase M16 inactive domain 180 355 5.3E-39 T 06-07-2017 IPR007863 Peptidase M16, C-terminal BWK49_RS19810 a0f3763a64d1a13b28c1f1d468dfe73e 439 SUPERFAMILY SSF63411 15 219 3.67E-58 T 06-07-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 BWK49_RS19810 a0f3763a64d1a13b28c1f1d468dfe73e 439 SUPERFAMILY SSF63411 249 429 9.0E-42 T 06-07-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 BWK49_RS19810 a0f3763a64d1a13b28c1f1d468dfe73e 439 Pfam PF00675 Insulinase (Peptidase family M16) 26 173 1.4E-33 T 06-07-2017 IPR011765 Peptidase M16, N-terminal BWK49_RS19810 a0f3763a64d1a13b28c1f1d468dfe73e 439 Gene3D G3DSA:3.30.830.10 16 221 4.2E-57 T 06-07-2017 IPR011237 Peptidase M16 domain GO:0046872 BWK49_RS10430 f01699d61a91185c8bda41e6d3eb6e6d 244 Pfam PF00975 Thioesterase domain 22 243 5.6E-38 T 06-07-2017 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 BWK49_RS10430 f01699d61a91185c8bda41e6d3eb6e6d 244 Gene3D G3DSA:3.40.50.1820 15 244 1.2E-27 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS10430 f01699d61a91185c8bda41e6d3eb6e6d 244 SUPERFAMILY SSF53474 13 242 4.53E-41 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS00825 768e49c4c23b72026dbf21cb9557c3bd 405 Pfam PF13527 Acetyltransferase (GNAT) domain 39 132 3.6E-19 T 06-07-2017 BWK49_RS00825 768e49c4c23b72026dbf21cb9557c3bd 405 Gene3D G3DSA:3.30.1050.10 305 394 4.7E-15 T 06-07-2017 IPR003033 SCP2 sterol-binding domain BWK49_RS00825 768e49c4c23b72026dbf21cb9557c3bd 405 SUPERFAMILY SSF55718 304 405 1.29E-18 T 06-07-2017 IPR003033 SCP2 sterol-binding domain BWK49_RS00825 768e49c4c23b72026dbf21cb9557c3bd 405 Gene3D G3DSA:3.40.630.30 4 135 3.6E-18 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase BWK49_RS00825 768e49c4c23b72026dbf21cb9557c3bd 405 SUPERFAMILY SSF55729 4 303 1.14E-55 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase BWK49_RS00825 768e49c4c23b72026dbf21cb9557c3bd 405 Pfam PF13530 Sterol carrier protein domain 181 400 3.2E-50 T 06-07-2017 IPR025559 Enhanced intracellular survival protein domain BWK49_RS00825 768e49c4c23b72026dbf21cb9557c3bd 405 Gene3D G3DSA:3.40.630.30 139 292 5.0E-30 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase BWK49_RS27795 f45bed6e5b93ebb190327f799cfe2111 466 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 59 74 6.2E-11 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS27795 f45bed6e5b93ebb190327f799cfe2111 466 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 150 176 6.2E-11 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS27795 f45bed6e5b93ebb190327f799cfe2111 466 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 80 100 6.2E-11 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS27795 f45bed6e5b93ebb190327f799cfe2111 466 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 29 54 6.2E-11 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS27795 f45bed6e5b93ebb190327f799cfe2111 466 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 187 450 5.3E-21 T 06-07-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 BWK49_RS27795 f45bed6e5b93ebb190327f799cfe2111 466 Gene3D G3DSA:2.102.10.10 42 159 1.0E-34 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS27795 f45bed6e5b93ebb190327f799cfe2111 466 Gene3D G3DSA:3.90.380.10 160 436 1.5E-21 T 06-07-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 BWK49_RS27795 f45bed6e5b93ebb190327f799cfe2111 466 SUPERFAMILY SSF55961 166 259 3.3E-32 T 06-07-2017 BWK49_RS27795 f45bed6e5b93ebb190327f799cfe2111 466 SUPERFAMILY SSF55961 299 453 3.3E-32 T 06-07-2017 BWK49_RS27795 f45bed6e5b93ebb190327f799cfe2111 466 SUPERFAMILY SSF50022 18 166 8.38E-42 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS27795 f45bed6e5b93ebb190327f799cfe2111 466 Pfam PF00355 Rieske [2Fe-2S] domain 45 134 1.1E-13 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS11815 0ec43cda8d8dc24d4e4283cbde57ff47 231 SUPERFAMILY SSF46689 12 89 2.72E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS11815 0ec43cda8d8dc24d4e4283cbde57ff47 231 Gene3D G3DSA:1.10.357.10 13 193 7.7E-24 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS11815 0ec43cda8d8dc24d4e4283cbde57ff47 231 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 1.5E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS11815 0ec43cda8d8dc24d4e4283cbde57ff47 231 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 1.5E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS11815 0ec43cda8d8dc24d4e4283cbde57ff47 231 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 65 7.6E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS19270 e00b73f346948a3365f0a9dc788f8069 519 Pfam PF00561 alpha/beta hydrolase fold 140 304 2.0E-11 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS19270 e00b73f346948a3365f0a9dc788f8069 519 Gene3D G3DSA:3.40.50.1820 214 347 1.9E-34 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS19270 e00b73f346948a3365f0a9dc788f8069 519 Gene3D G3DSA:3.40.50.1820 86 170 1.9E-34 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS19270 e00b73f346948a3365f0a9dc788f8069 519 Gene3D G3DSA:3.40.50.1820 386 495 1.9E-34 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS19270 e00b73f346948a3365f0a9dc788f8069 519 SUPERFAMILY SSF53474 117 171 6.66E-19 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS19270 e00b73f346948a3365f0a9dc788f8069 519 SUPERFAMILY SSF53474 347 490 6.66E-19 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS19270 e00b73f346948a3365f0a9dc788f8069 519 SUPERFAMILY SSF53474 216 270 6.66E-19 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS19270 e00b73f346948a3365f0a9dc788f8069 519 Pfam PF08386 TAP-like protein 416 517 9.1E-20 T 06-07-2017 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal BWK49_RS23360 7d7d63f359f83b3990d669b908f90f94 275 SUPERFAMILY SSF53167 12 271 5.29E-78 T 06-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 BWK49_RS23360 7d7d63f359f83b3990d669b908f90f94 275 TIGRFAM TIGR01697 PNPH-PUNA-XAPA: inosine/guanosine/xanthosine phosphorylase family 29 269 1.5E-84 T 06-07-2017 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-74217|Reactome: R-HSA-74259 BWK49_RS23360 7d7d63f359f83b3990d669b908f90f94 275 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 87 128 - T 06-07-2017 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 BWK49_RS23360 7d7d63f359f83b3990d669b908f90f94 275 Gene3D G3DSA:3.40.50.1580 11 271 4.2E-91 T 06-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 BWK49_RS23360 7d7d63f359f83b3990d669b908f90f94 275 PIRSF PIRSF000477 1 272 2.1E-103 T 06-07-2017 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-74217|Reactome: R-HSA-74259 BWK49_RS23360 7d7d63f359f83b3990d669b908f90f94 275 Pfam PF01048 Phosphorylase superfamily 29 269 1.6E-44 T 06-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 BWK49_RS23360 7d7d63f359f83b3990d669b908f90f94 275 TIGRFAM TIGR01698 PUNP: purine nucleotide phosphorylase 29 268 3.0E-106 T 06-07-2017 IPR011269 Putative purine nucleotide phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 BWK49_RS04135 67b8ae3256294b3ff48a683b4646827c 308 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 296 1.6E-16 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS04135 67b8ae3256294b3ff48a683b4646827c 308 Gene3D G3DSA:1.10.3720.10 14 296 3.9E-33 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS04135 67b8ae3256294b3ff48a683b4646827c 308 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 3 297 1.1E-80 T 06-07-2017 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 BWK49_RS04135 67b8ae3256294b3ff48a683b4646827c 308 SUPERFAMILY SSF161098 36 295 5.49E-31 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS18655 52f0b5e019bdf90807dbf912dd77ae57 883 Pfam PF14403 Circularly permuted ATP-grasp type 2 116 488 1.3E-124 T 06-07-2017 IPR025841 Circularly permuted ATP-grasp type 2 BWK49_RS18655 52f0b5e019bdf90807dbf912dd77ae57 883 SUPERFAMILY SSF56059 84 229 2.37E-6 T 06-07-2017 BWK49_RS18655 52f0b5e019bdf90807dbf912dd77ae57 883 Pfam PF04168 A predicted alpha-helical domain with a conserved ER motif. 540 860 8.8E-63 T 06-07-2017 IPR007296 Domain of unknown function DUF403 BWK49_RS00285 b26ff9b0efc05a8a0558f63190b69a34 605 SMART SM00062 94 312 3.3E-38 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF BWK49_RS00285 b26ff9b0efc05a8a0558f63190b69a34 605 Gene3D G3DSA:3.40.190.10 90 214 5.5E-29 T 06-07-2017 BWK49_RS00285 b26ff9b0efc05a8a0558f63190b69a34 605 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 374 472 1.1E-17 T 06-07-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 BWK49_RS00285 b26ff9b0efc05a8a0558f63190b69a34 605 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 393 582 1.5E-22 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS00285 b26ff9b0efc05a8a0558f63190b69a34 605 Gene3D G3DSA:1.10.3720.10 375 582 4.5E-43 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS00285 b26ff9b0efc05a8a0558f63190b69a34 605 Gene3D G3DSA:3.40.190.10 225 312 5.6E-9 T 06-07-2017 BWK49_RS00285 b26ff9b0efc05a8a0558f63190b69a34 605 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 95 310 4.1E-43 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF BWK49_RS00285 b26ff9b0efc05a8a0558f63190b69a34 605 SUPERFAMILY SSF53850 92 312 1.09E-47 T 06-07-2017 BWK49_RS00285 b26ff9b0efc05a8a0558f63190b69a34 605 SUPERFAMILY SSF161098 375 581 1.96E-36 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS28340 c6d9f6782995ba367f49e8f853024054 117 Pfam PF00085 Thioredoxin 11 109 8.0E-34 T 06-07-2017 IPR013766 Thioredoxin domain GO:0045454 BWK49_RS28340 c6d9f6782995ba367f49e8f853024054 117 Gene3D G3DSA:3.40.30.10 10 110 1.1E-37 T 06-07-2017 IPR012336 Thioredoxin-like fold BWK49_RS28340 c6d9f6782995ba367f49e8f853024054 117 ProSitePatterns PS00194 Thioredoxin family active site. 30 48 - T 06-07-2017 IPR017937 Thioredoxin, conserved site GO:0045454 BWK49_RS28340 c6d9f6782995ba367f49e8f853024054 117 PRINTS PR00421 Thioredoxin family signature 37 46 2.0E-8 T 06-07-2017 BWK49_RS28340 c6d9f6782995ba367f49e8f853024054 117 PRINTS PR00421 Thioredoxin family signature 29 37 2.0E-8 T 06-07-2017 BWK49_RS28340 c6d9f6782995ba367f49e8f853024054 117 PRINTS PR00421 Thioredoxin family signature 77 88 2.0E-8 T 06-07-2017 BWK49_RS28340 c6d9f6782995ba367f49e8f853024054 117 SUPERFAMILY SSF52833 9 113 2.12E-38 T 06-07-2017 IPR012336 Thioredoxin-like fold BWK49_RS28340 c6d9f6782995ba367f49e8f853024054 117 TIGRFAM TIGR01068 thioredoxin: thioredoxin 14 111 1.7E-39 T 06-07-2017 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 BWK49_RS28340 c6d9f6782995ba367f49e8f853024054 117 PIRSF PIRSF000077 7 113 8.7E-45 T 06-07-2017 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 BWK49_RS08000 0b98375fb2a375f5eceb014f76aaf117 204 Gene3D G3DSA:1.10.10.10 6 52 5.9E-7 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS08000 0b98375fb2a375f5eceb014f76aaf117 204 SUPERFAMILY SSF46785 2 55 4.43E-6 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS11845 e402f1923a0011fbbfb4e9db8a0c5154 131 Pfam PF04075 Domain of unknown function (DUF385) 26 88 1.3E-4 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 BWK49_RS11845 e402f1923a0011fbbfb4e9db8a0c5154 131 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 22 110 3.2E-17 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 BWK49_RS16735 062a2afa4701b53d4328bbffad3b621d 247 Pfam PF13618 Gluconate 2-dehydrogenase subunit 3 76 205 3.0E-14 T 06-07-2017 IPR027056 Gluconate 2-dehydrogenase subunit 3 KEGG: 00030+1.1.99.3|MetaCyc: PWY-7165 BWK49_RS15125 31f8d333904da4d189914bf69e288617 547 Gene3D G3DSA:3.40.50.970 11 180 5.9E-47 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS15125 31f8d333904da4d189914bf69e288617 547 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 385 532 9.1E-32 T 06-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 BWK49_RS15125 31f8d333904da4d189914bf69e288617 547 Gene3D G3DSA:3.40.50.970 358 541 8.2E-52 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS15125 31f8d333904da4d189914bf69e288617 547 SUPERFAMILY SSF52518 362 541 1.24E-50 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS15125 31f8d333904da4d189914bf69e288617 547 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 422 441 - T 06-07-2017 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 BWK49_RS15125 31f8d333904da4d189914bf69e288617 547 Gene3D G3DSA:3.40.50.1220 190 331 1.7E-31 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain BWK49_RS15125 31f8d333904da4d189914bf69e288617 547 SUPERFAMILY SSF52467 164 349 6.98E-31 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain BWK49_RS15125 31f8d333904da4d189914bf69e288617 547 SUPERFAMILY SSF52518 11 182 4.91E-39 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS15125 31f8d333904da4d189914bf69e288617 547 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 200 326 5.7E-20 T 06-07-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 BWK49_RS15125 31f8d333904da4d189914bf69e288617 547 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 13 178 5.3E-43 T 06-07-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 BWK49_RS05505 8bdeab69fee52b9c76b35f910526400b 405 Gene3D G3DSA:2.40.110.10 127 222 6.5E-37 T 06-07-2017 BWK49_RS05505 8bdeab69fee52b9c76b35f910526400b 405 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 128 220 2.3E-23 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 BWK49_RS05505 8bdeab69fee52b9c76b35f910526400b 405 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 124 1.5E-23 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS05505 8bdeab69fee52b9c76b35f910526400b 405 SUPERFAMILY SSF47203 234 399 3.14E-19 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS05505 8bdeab69fee52b9c76b35f910526400b 405 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 234 396 2.0E-22 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS05505 8bdeab69fee52b9c76b35f910526400b 405 SUPERFAMILY SSF56645 2 245 3.01E-76 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS05505 8bdeab69fee52b9c76b35f910526400b 405 Gene3D G3DSA:1.20.140.10 223 403 5.6E-29 T 06-07-2017 BWK49_RS05505 8bdeab69fee52b9c76b35f910526400b 405 Gene3D G3DSA:1.10.540.10 1 125 6.5E-27 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS23285 e651accf45ea693c31439e9723e6d0d9 335 Gene3D G3DSA:1.20.58.340 145 257 3.8E-33 T 06-07-2017 BWK49_RS23285 e651accf45ea693c31439e9723e6d0d9 335 SUPERFAMILY SSF143865 6 268 6.93E-50 T 06-07-2017 BWK49_RS23285 e651accf45ea693c31439e9723e6d0d9 335 Gene3D G3DSA:3.30.460.20 25 140 7.1E-12 T 06-07-2017 BWK49_RS23285 e651accf45ea693c31439e9723e6d0d9 335 Gene3D G3DSA:1.20.58.340 261 335 3.1E-18 T 06-07-2017 BWK49_RS23285 e651accf45ea693c31439e9723e6d0d9 335 Pfam PF01544 CorA-like Mg2+ transporter protein 35 331 1.3E-61 T 06-07-2017 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 BWK49_RS23285 e651accf45ea693c31439e9723e6d0d9 335 SUPERFAMILY SSF144083 271 332 1.57E-14 T 06-07-2017 BWK49_RS00110 a91756a80e3194adce3e79745f8f665c 423 SMART SM00220 13 272 1.6E-62 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 BWK49_RS00110 a91756a80e3194adce3e79745f8f665c 423 Pfam PF00069 Protein kinase domain 13 261 5.0E-47 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 BWK49_RS00110 a91756a80e3194adce3e79745f8f665c 423 SUPERFAMILY SSF56112 11 307 4.72E-76 T 06-07-2017 IPR011009 Protein kinase-like domain BWK49_RS00110 a91756a80e3194adce3e79745f8f665c 423 Gene3D G3DSA:1.10.510.10 103 327 1.2E-45 T 06-07-2017 BWK49_RS00110 a91756a80e3194adce3e79745f8f665c 423 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 137 149 - T 06-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 BWK49_RS00110 a91756a80e3194adce3e79745f8f665c 423 Gene3D G3DSA:3.30.200.20 6 97 1.1E-25 T 06-07-2017 BWK49_RS26025 09942d95ade8319acabb878165397f7d 298 SUPERFAMILY SSF160240 217 289 6.28E-6 T 06-07-2017 BWK49_RS26025 09942d95ade8319acabb878165397f7d 298 Pfam PF01545 Cation efflux family 24 212 8.7E-37 T 06-07-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 BWK49_RS26025 09942d95ade8319acabb878165397f7d 298 SUPERFAMILY SSF161111 21 214 3.4E-45 T 06-07-2017 BWK49_RS26025 09942d95ade8319acabb878165397f7d 298 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 21 287 3.7E-65 T 06-07-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 BWK49_RS26025 09942d95ade8319acabb878165397f7d 298 Gene3D G3DSA:1.20.1510.10 21 212 3.9E-46 T 06-07-2017 IPR027469 Cation efflux protein transmembrane domain BWK49_RS25075 73e96fed712781718fc3c53b34f84e61 379 ProSitePatterns PS00455 Putative AMP-binding domain signature. 56 67 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS25075 73e96fed712781718fc3c53b34f84e61 379 SUPERFAMILY SSF56801 47 376 5.49E-70 T 06-07-2017 BWK49_RS25075 73e96fed712781718fc3c53b34f84e61 379 Pfam PF00501 AMP-binding enzyme 49 278 2.7E-27 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS25075 73e96fed712781718fc3c53b34f84e61 379 Gene3D G3DSA:3.40.50.980 51 210 2.6E-17 T 06-07-2017 BWK49_RS25075 73e96fed712781718fc3c53b34f84e61 379 Gene3D G3DSA:3.30.300.30 273 372 1.2E-24 T 06-07-2017 BWK49_RS25075 73e96fed712781718fc3c53b34f84e61 379 Gene3D G3DSA:2.30.38.10 213 272 1.5E-7 T 06-07-2017 BWK49_RS25075 73e96fed712781718fc3c53b34f84e61 379 Pfam PF13193 AMP-binding enzyme C-terminal domain 288 363 1.2E-18 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS12600 86c268c41e68ff3dd7230ff17dfef28c 109 Pfam PF16525 Haemophore, haem-binding 33 109 1.1E-35 T 06-07-2017 IPR032407 Haemophore, haem-binding GO:0020037 BWK49_RS12600 86c268c41e68ff3dd7230ff17dfef28c 109 TIGRFAM TIGR04529 MTB_hemophore: hemophore-related protein, Rv0203/Rv1174c family 35 108 2.0E-28 T 06-07-2017 IPR032407 Haemophore, haem-binding GO:0020037 BWK49_RS06285 a20e16446aa3a0a93513c3e32fb431af 332 Gene3D G3DSA:1.20.140.10 194 326 4.8E-31 T 06-07-2017 BWK49_RS06285 a20e16446aa3a0a93513c3e32fb431af 332 SUPERFAMILY SSF47203 191 326 2.42E-32 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS06285 a20e16446aa3a0a93513c3e32fb431af 332 SUPERFAMILY SSF56645 1 180 7.05E-16 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS06285 a20e16446aa3a0a93513c3e32fb431af 332 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 194 325 6.6E-25 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS06285 a20e16446aa3a0a93513c3e32fb431af 332 Gene3D G3DSA:1.10.540.10 3 84 1.3E-8 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS06285 a20e16446aa3a0a93513c3e32fb431af 332 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 79 5.6E-5 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS17455 534541479e9e0958e8057aa8d56e990f 736 SUPERFAMILY SSF51011 621 733 3.6E-23 T 06-07-2017 BWK49_RS17455 534541479e9e0958e8057aa8d56e990f 736 SUPERFAMILY SSF51445 172 610 8.94E-133 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily BWK49_RS17455 534541479e9e0958e8057aa8d56e990f 736 TIGRFAM TIGR02100 glgX_debranch: glycogen debranching enzyme GlgX 24 733 6.2E-295 T 06-07-2017 IPR011837 Glycogen debranching enzyme, GlgX type GO:0004133|GO:0004553|GO:0005980 BWK49_RS17455 534541479e9e0958e8057aa8d56e990f 736 SUPERFAMILY SSF81296 157 180 1.62E-41 T 06-07-2017 IPR014756 Immunoglobulin E-set BWK49_RS17455 534541479e9e0958e8057aa8d56e990f 736 SUPERFAMILY SSF81296 23 130 1.62E-41 T 06-07-2017 IPR014756 Immunoglobulin E-set BWK49_RS17455 534541479e9e0958e8057aa8d56e990f 736 Gene3D G3DSA:2.60.40.10 163 184 3.6E-56 T 06-07-2017 IPR013783 Immunoglobulin-like fold BWK49_RS17455 534541479e9e0958e8057aa8d56e990f 736 Gene3D G3DSA:2.60.40.10 23 128 3.6E-56 T 06-07-2017 IPR013783 Immunoglobulin-like fold BWK49_RS17455 534541479e9e0958e8057aa8d56e990f 736 Gene3D G3DSA:2.60.40.1180 620 733 2.1E-31 T 06-07-2017 IPR013780 Glycosyl hydrolase, all-beta BWK49_RS17455 534541479e9e0958e8057aa8d56e990f 736 SMART SM00642 187 599 1.5E-6 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 BWK49_RS17455 534541479e9e0958e8057aa8d56e990f 736 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 28 114 8.2E-19 T 06-07-2017 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 BWK49_RS17455 534541479e9e0958e8057aa8d56e990f 736 Pfam PF00128 Alpha amylase, catalytic domain 221 307 2.6E-8 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 BWK49_RS17455 534541479e9e0958e8057aa8d56e990f 736 Pfam PF00128 Alpha amylase, catalytic domain 342 561 1.5E-5 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 BWK49_RS17455 534541479e9e0958e8057aa8d56e990f 736 Gene3D G3DSA:3.20.20.80 185 607 1.4E-124 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 BWK49_RS03240 e2a8e14b842203533546b91e3e7e3e26 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 65 1.0E-15 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS03240 e2a8e14b842203533546b91e3e7e3e26 199 SUPERFAMILY SSF46689 15 76 4.04E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS03240 e2a8e14b842203533546b91e3e7e3e26 199 Gene3D G3DSA:1.10.357.10 14 193 4.6E-33 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS03240 e2a8e14b842203533546b91e3e7e3e26 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 6.0E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS03240 e2a8e14b842203533546b91e3e7e3e26 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 6.0E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS27520 e258fe69a2ba8f4edb1ea26de16986b5 339 Pfam PF01370 NAD dependent epimerase/dehydratase family 7 232 1.8E-25 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 BWK49_RS27520 e258fe69a2ba8f4edb1ea26de16986b5 339 Gene3D G3DSA:3.40.50.720 7 321 1.2E-50 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS27520 e258fe69a2ba8f4edb1ea26de16986b5 339 SUPERFAMILY SSF51735 7 326 2.24E-57 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS03385 6264ef997c1d4547833bd21b3d85fe1f 165 Gene3D G3DSA:2.30.110.10 44 104 2.7E-4 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 BWK49_RS03385 6264ef997c1d4547833bd21b3d85fe1f 165 SUPERFAMILY SSF50475 41 146 3.65E-7 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 BWK49_RS03385 6264ef997c1d4547833bd21b3d85fe1f 165 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 41 148 5.9E-29 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 BWK49_RS03385 6264ef997c1d4547833bd21b3d85fe1f 165 Pfam PF04075 Domain of unknown function (DUF385) 22 149 3.0E-42 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 BWK49_RS12570 9f1b1226df292365515b650339fffbf2 209 Pfam PF13489 Methyltransferase domain 32 189 6.2E-18 T 06-07-2017 BWK49_RS12570 9f1b1226df292365515b650339fffbf2 209 Gene3D G3DSA:3.40.50.150 25 192 1.4E-37 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS12570 9f1b1226df292365515b650339fffbf2 209 SUPERFAMILY SSF53335 10 160 1.49E-38 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS07410 7ec3596362e50fb979df2c473dac51c5 362 Gene3D G3DSA:1.10.530.10 257 360 7.0E-40 T 06-07-2017 BWK49_RS07410 7ec3596362e50fb979df2c473dac51c5 362 SUPERFAMILY SSF53955 279 360 3.37E-30 T 06-07-2017 IPR023346 Lysozyme-like domain BWK49_RS07410 7ec3596362e50fb979df2c473dac51c5 362 Pfam PF07501 G5 domain 198 271 4.2E-18 T 06-07-2017 IPR011098 G5 domain BWK49_RS07410 7ec3596362e50fb979df2c473dac51c5 362 Pfam PF06737 Transglycosylase-like domain 282 355 9.0E-33 T 06-07-2017 IPR010618 Transglycosylase-like BWK49_RS07410 7ec3596362e50fb979df2c473dac51c5 362 Pfam PF03990 Domain of unknown function (DUF348) 27 67 4.1E-9 T 06-07-2017 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 BWK49_RS07410 7ec3596362e50fb979df2c473dac51c5 362 Pfam PF03990 Domain of unknown function (DUF348) 85 114 5.3E-7 T 06-07-2017 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 BWK49_RS07410 7ec3596362e50fb979df2c473dac51c5 362 Pfam PF03990 Domain of unknown function (DUF348) 141 180 1.2E-6 T 06-07-2017 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 BWK49_RS07410 7ec3596362e50fb979df2c473dac51c5 362 SMART SM01208 194 272 2.3E-18 T 06-07-2017 IPR011098 G5 domain BWK49_RS18370 d2cb1b080163596eb39b5ce37cdd83e9 341 Gene3D G3DSA:3.40.430.10 155 338 1.1E-50 T 06-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 BWK49_RS18370 d2cb1b080163596eb39b5ce37cdd83e9 341 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 57 95 - T 06-07-2017 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 BWK49_RS18370 d2cb1b080163596eb39b5ce37cdd83e9 341 SUPERFAMILY SSF53597 154 336 4.68E-44 T 06-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 BWK49_RS18370 d2cb1b080163596eb39b5ce37cdd83e9 341 Gene3D G3DSA:3.40.140.10 11 154 4.0E-25 T 06-07-2017 BWK49_RS18370 d2cb1b080163596eb39b5ce37cdd83e9 341 SUPERFAMILY SSF53927 12 139 2.51E-37 T 06-07-2017 IPR016193 Cytidine deaminase-like GO:0003824 BWK49_RS18370 d2cb1b080163596eb39b5ce37cdd83e9 341 Pfam PF01872 RibD C-terminal domain 154 334 3.1E-46 T 06-07-2017 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 BWK49_RS18370 d2cb1b080163596eb39b5ce37cdd83e9 341 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 11 106 4.2E-14 T 06-07-2017 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 BWK49_RS18370 d2cb1b080163596eb39b5ce37cdd83e9 341 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 13 334 1.6E-94 T 06-07-2017 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 BWK49_RS15480 acd20366eaf27b4d515d50406c901613 374 Gene3D G3DSA:3.40.50.150 115 258 1.7E-4 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS15480 acd20366eaf27b4d515d50406c901613 374 Pfam PF05711 Macrocin-O-methyltransferase (TylF) 119 275 2.0E-8 T 06-07-2017 IPR008884 Macrocin-O-methyltransferase BWK49_RS15480 acd20366eaf27b4d515d50406c901613 374 SUPERFAMILY SSF53335 192 272 8.91E-8 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS15480 acd20366eaf27b4d515d50406c901613 374 SUPERFAMILY SSF53335 114 151 8.91E-8 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS03300 3dd288eacb880f0322cfd9e521ee8870 316 SUPERFAMILY SSF56645 1 125 2.68E-14 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS03300 3dd288eacb880f0322cfd9e521ee8870 316 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 184 291 5.6E-22 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS03300 3dd288eacb880f0322cfd9e521ee8870 316 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 2 93 1.4E-12 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS03300 3dd288eacb880f0322cfd9e521ee8870 316 Gene3D G3DSA:1.10.540.10 2 88 1.3E-12 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS03300 3dd288eacb880f0322cfd9e521ee8870 316 SUPERFAMILY SSF47203 181 312 2.9E-32 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS03300 3dd288eacb880f0322cfd9e521ee8870 316 Gene3D G3DSA:1.20.140.10 180 294 1.2E-29 T 06-07-2017 BWK49_RS25115 669f0b9fad2fe297b62155d6b5718fab 290 PIRSF PIRSF005355 1 290 2.9E-81 T 06-07-2017 IPR026046 UbiA prenyltransferase domain containing protein 1 GO:0004659 Reactome: R-HSA-6806664 BWK49_RS25115 669f0b9fad2fe297b62155d6b5718fab 290 TIGRFAM TIGR00751 menA: 1,4-dihydroxy-2-naphthoate octaprenyltransferase 12 284 5.3E-113 T 06-07-2017 BWK49_RS25115 669f0b9fad2fe297b62155d6b5718fab 290 Pfam PF01040 UbiA prenyltransferase family 20 250 1.3E-30 T 06-07-2017 IPR000537 UbiA prenyltransferase family GO:0004659|GO:0016021 BWK49_RS25115 669f0b9fad2fe297b62155d6b5718fab 290 Hamap MF_01937 1,4-dihydroxy-2-naphthoate octaprenyltransferase [menA]. 3 286 20.566 T 06-07-2017 IPR004657 1,4-dihydroxy-2-naphthoate octaprenyltransferase GO:0009234|GO:0016021|GO:0046428 KEGG: 00130+2.5.1.74|MetaCyc: PWY-5839|MetaCyc: PWY-5851|MetaCyc: PWY-5852|MetaCyc: PWY-5853|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 BWK49_RS24155 dcf2b078d94a71f93fd56a82d64571e6 222 SUPERFAMILY SSF56719 6 89 4.71E-5 T 06-07-2017 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 BWK49_RS24155 dcf2b078d94a71f93fd56a82d64571e6 222 Gene3D G3DSA:3.40.630.30 97 197 2.1E-12 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase BWK49_RS24155 dcf2b078d94a71f93fd56a82d64571e6 222 SUPERFAMILY SSF55729 96 198 2.74E-13 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase BWK49_RS24155 dcf2b078d94a71f93fd56a82d64571e6 222 Pfam PF00583 Acetyltransferase (GNAT) family 158 203 3.1E-4 T 06-07-2017 IPR000182 GNAT domain GO:0008080 BWK49_RS09045 6f22625ef06a2f30b0fef6d00101a4a1 357 SUPERFAMILY SSF55073 199 351 2.75E-32 T 06-07-2017 IPR029787 Nucleotide cyclase BWK49_RS09045 6f22625ef06a2f30b0fef6d00101a4a1 357 Pfam PF00990 Diguanylate cyclase, GGDEF domain 194 349 6.9E-30 T 06-07-2017 IPR000160 GGDEF domain BWK49_RS09045 6f22625ef06a2f30b0fef6d00101a4a1 357 SMART SM00267 181 353 6.3E-35 T 06-07-2017 IPR000160 GGDEF domain BWK49_RS09045 6f22625ef06a2f30b0fef6d00101a4a1 357 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 193 351 1.5E-28 T 06-07-2017 IPR000160 GGDEF domain BWK49_RS09045 6f22625ef06a2f30b0fef6d00101a4a1 357 Gene3D G3DSA:3.30.70.270 196 351 8.5E-38 T 06-07-2017 BWK49_RS17260 ba223fc92ab308b6493f7964bfe64c8e 535 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 10 279 15.001 T 06-07-2017 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 BWK49_RS17260 ba223fc92ab308b6493f7964bfe64c8e 535 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 12 272 2.7E-37 T 06-07-2017 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 BWK49_RS17260 ba223fc92ab308b6493f7964bfe64c8e 535 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 15 273 1.9E-58 T 06-07-2017 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 BWK49_RS17260 ba223fc92ab308b6493f7964bfe64c8e 535 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 143 155 - T 06-07-2017 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 BWK49_RS06350 56d3c5bbd94445c9d835a214b629d238 340 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 11 292 1.9E-70 T 06-07-2017 IPR005693 Virulence factor Mce protein BWK49_RS06350 56d3c5bbd94445c9d835a214b629d238 340 Pfam PF02470 MlaD protein 39 111 8.2E-17 T 06-07-2017 IPR003399 Mce/MlaD BWK49_RS11170 7de0b0d1647332b0808d4f0f1761ecdb 232 Gene3D G3DSA:1.10.10.10 28 86 1.5E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS11170 7de0b0d1647332b0808d4f0f1761ecdb 232 SUPERFAMILY SSF46785 26 198 9.69E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS11170 7de0b0d1647332b0808d4f0f1761ecdb 232 Pfam PF09339 IclR helix-turn-helix domain 27 70 5.8E-5 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 BWK49_RS28925 232dcbf22ddb6751263a5396668aac92 550 Pfam PF01385 Probable transposase 281 394 2.0E-27 T 06-07-2017 IPR001959 Probable transposase, IS891/IS1136/IS1341 BWK49_RS28925 232dcbf22ddb6751263a5396668aac92 550 Pfam PF07282 Putative transposase DNA-binding domain 417 485 2.9E-8 T 06-07-2017 IPR010095 Transposase IS605, OrfB, C-terminal BWK49_RS28925 232dcbf22ddb6751263a5396668aac92 550 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 366 438 1.6E-6 T 06-07-2017 IPR010095 Transposase IS605, OrfB, C-terminal BWK49_RS07595 56a852c0fa20e666d48c1d000dc15e2b 387 Pfam PF00823 PPE family 7 163 2.8E-51 T 06-07-2017 IPR000030 PPE family BWK49_RS07595 56a852c0fa20e666d48c1d000dc15e2b 387 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 302 383 1.8E-18 T 06-07-2017 IPR022171 PPE family, C-terminal BWK49_RS07595 56a852c0fa20e666d48c1d000dc15e2b 387 SUPERFAMILY SSF140459 5 171 2.88E-51 T 06-07-2017 BWK49_RS01495 d3a9f0053111c5b14f77df8d892917bf 190 SUPERFAMILY SSF49482 4 175 2.75E-39 T 06-07-2017 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 BWK49_RS01495 d3a9f0053111c5b14f77df8d892917bf 190 Pfam PF00775 Dioxygenase 14 106 4.6E-14 T 06-07-2017 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 BWK49_RS01495 d3a9f0053111c5b14f77df8d892917bf 190 TIGRFAM TIGR02423 protocat_alph: protocatechuate 3,4-dioxygenase, alpha subunit 8 183 5.5E-48 T 06-07-2017 IPR012786 Protocatechuate 3,4-dioxygenase, alpha subunit GO:0005506|GO:0018578|GO:0019439|GO:0055114 KEGG: 00362+1.13.11.3|KEGG: 00624+1.13.11.3 BWK49_RS01495 d3a9f0053111c5b14f77df8d892917bf 190 Gene3D G3DSA:2.60.130.10 6 182 7.8E-51 T 06-07-2017 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 BWK49_RS13785 8a048f57b75581303540f2e0e3b58d8b 321 SUPERFAMILY SSF52151 5 306 1.23E-42 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 BWK49_RS13785 8a048f57b75581303540f2e0e3b58d8b 321 Pfam PF01734 Patatin-like phospholipase 8 207 4.7E-30 T 06-07-2017 IPR002641 Patatin/Phospholipase A2-related GO:0006629 BWK49_RS13785 8a048f57b75581303540f2e0e3b58d8b 321 Gene3D G3DSA:3.40.1090.10 8 202 2.1E-13 T 06-07-2017 BWK49_RS19170 43c02a443740099fae380befdd75b01a 314 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 2.4E-18 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS19170 43c02a443740099fae380befdd75b01a 314 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 136 152 2.4E-18 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS19170 43c02a443740099fae380befdd75b01a 314 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 2.4E-18 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS19170 43c02a443740099fae380befdd75b01a 314 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 189 2.4E-18 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS19170 43c02a443740099fae380befdd75b01a 314 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 193 210 2.4E-18 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS19170 43c02a443740099fae380befdd75b01a 314 SUPERFAMILY SSF51735 245 282 3.64E-55 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS19170 43c02a443740099fae380befdd75b01a 314 SUPERFAMILY SSF51735 2 217 3.64E-55 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS19170 43c02a443740099fae380befdd75b01a 314 Pfam PF00106 short chain dehydrogenase 12 216 1.3E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS19170 43c02a443740099fae380befdd75b01a 314 Gene3D G3DSA:3.40.50.720 3 232 1.1E-56 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS19170 43c02a443740099fae380befdd75b01a 314 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 87 98 6.4E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS19170 43c02a443740099fae380befdd75b01a 314 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 142 150 6.4E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS19170 43c02a443740099fae380befdd75b01a 314 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 170 189 6.4E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS21220 9009490a0d5f15554206dddfda257286 442 Gene3D G3DSA:3.40.50.620 2 152 7.2E-40 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold BWK49_RS21220 9009490a0d5f15554206dddfda257286 442 Gene3D G3DSA:1.10.579.10 260 441 1.5E-69 T 06-07-2017 BWK49_RS21220 9009490a0d5f15554206dddfda257286 442 PRINTS PR00147 DNA photolyase signature 323 341 3.7E-24 T 06-07-2017 IPR002081 Cryptochrome/DNA photolyase class 1 BWK49_RS21220 9009490a0d5f15554206dddfda257286 442 PRINTS PR00147 DNA photolyase signature 362 376 3.7E-24 T 06-07-2017 IPR002081 Cryptochrome/DNA photolyase class 1 BWK49_RS21220 9009490a0d5f15554206dddfda257286 442 PRINTS PR00147 DNA photolyase signature 131 147 3.7E-24 T 06-07-2017 IPR002081 Cryptochrome/DNA photolyase class 1 BWK49_RS21220 9009490a0d5f15554206dddfda257286 442 PRINTS PR00147 DNA photolyase signature 303 319 3.7E-24 T 06-07-2017 IPR002081 Cryptochrome/DNA photolyase class 1 BWK49_RS21220 9009490a0d5f15554206dddfda257286 442 Pfam PF03441 FAD binding domain of DNA photolyase 251 440 4.1E-77 T 06-07-2017 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 BWK49_RS21220 9009490a0d5f15554206dddfda257286 442 Pfam PF00875 DNA photolyase 3 150 2.0E-40 T 06-07-2017 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-1368108|Reactome: R-HSA-400253 BWK49_RS21220 9009490a0d5f15554206dddfda257286 442 Gene3D G3DSA:1.25.40.80 186 259 2.4E-32 T 06-07-2017 BWK49_RS21220 9009490a0d5f15554206dddfda257286 442 SUPERFAMILY SSF48173 183 440 1.96E-94 T 06-07-2017 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 BWK49_RS21220 9009490a0d5f15554206dddfda257286 442 SUPERFAMILY SSF52425 3 167 4.58E-43 T 06-07-2017 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-1368108|Reactome: R-HSA-400253 BWK49_RS19525 bc500ca4203556e4fd6ef7f229e50973 386 Gene3D G3DSA:1.20.140.10 226 384 5.0E-59 T 06-07-2017 BWK49_RS19525 bc500ca4203556e4fd6ef7f229e50973 386 SUPERFAMILY SSF47203 234 384 7.09E-49 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS19525 bc500ca4203556e4fd6ef7f229e50973 386 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 343 362 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 BWK49_RS19525 bc500ca4203556e4fd6ef7f229e50973 386 Gene3D G3DSA:2.40.110.10 129 225 7.0E-40 T 06-07-2017 BWK49_RS19525 bc500ca4203556e4fd6ef7f229e50973 386 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 129 224 1.1E-24 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 BWK49_RS19525 bc500ca4203556e4fd6ef7f229e50973 386 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 14 125 4.4E-32 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS19525 bc500ca4203556e4fd6ef7f229e50973 386 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 236 384 5.4E-47 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS19525 bc500ca4203556e4fd6ef7f229e50973 386 SUPERFAMILY SSF56645 9 248 9.03E-83 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS19525 bc500ca4203556e4fd6ef7f229e50973 386 Gene3D G3DSA:1.10.540.10 12 127 7.6E-33 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS19255 fc4f9ab9cb7af2e90e9c186cf6786a3c 169 SUPERFAMILY SSF55729 17 168 5.66E-30 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase BWK49_RS19255 fc4f9ab9cb7af2e90e9c186cf6786a3c 169 Pfam PF13673 Acetyltransferase (GNAT) domain 35 150 1.4E-16 T 06-07-2017 IPR000182 GNAT domain GO:0008080 BWK49_RS19255 fc4f9ab9cb7af2e90e9c186cf6786a3c 169 Gene3D G3DSA:3.40.630.30 14 168 2.9E-33 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase BWK49_RS16450 a7b134f7e1739b9803a22c08f7399ccc 198 Pfam PF03713 Domain of unknown function (DUF305) 50 195 3.7E-48 T 06-07-2017 IPR005183 Domain of unknown function DUF305 BWK49_RS16450 a7b134f7e1739b9803a22c08f7399ccc 198 Gene3D G3DSA:1.20.1260.10 45 197 1.2E-57 T 06-07-2017 IPR012347 Ferritin-related BWK49_RS14390 be8404674c4a682d5666f4fedad74a5a 182 Gene3D G3DSA:1.10.357.10 45 182 3.0E-33 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS14390 be8404674c4a682d5666f4fedad74a5a 182 Pfam PF00440 Bacterial regulatory proteins, tetR family 1 47 1.4E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS14390 be8404674c4a682d5666f4fedad74a5a 182 Gene3D G3DSA:1.10.10.60 1 44 1.2E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS14390 be8404674c4a682d5666f4fedad74a5a 182 SUPERFAMILY SSF46689 1 72 3.49E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS14390 be8404674c4a682d5666f4fedad74a5a 182 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 1 14 6.4E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS14390 be8404674c4a682d5666f4fedad74a5a 182 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 45 6.4E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS14390 be8404674c4a682d5666f4fedad74a5a 182 SUPERFAMILY SSF48498 70 181 8.9E-19 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS10285 1f60764bb74bbd015f9525d719e30156 305 SMART SM00422 63 131 1.7E-9 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 BWK49_RS10285 1f60764bb74bbd015f9525d719e30156 305 SUPERFAMILY SSF46955 63 134 9.89E-16 T 06-07-2017 IPR009061 Putative DNA-binding domain BWK49_RS10285 1f60764bb74bbd015f9525d719e30156 305 Gene3D G3DSA:1.10.1660.10 63 136 4.3E-18 T 06-07-2017 BWK49_RS10285 1f60764bb74bbd015f9525d719e30156 305 Pfam PF13411 MerR HTH family regulatory protein 63 130 1.3E-18 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 BWK49_RS28155 2c9711349ce03a5cc5d2bf02e70a37fc 212 Gene3D G3DSA:1.10.10.60 19 68 2.1E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS28155 2c9711349ce03a5cc5d2bf02e70a37fc 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 31 70 1.3E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS28155 2c9711349ce03a5cc5d2bf02e70a37fc 212 ProSitePatterns PS01081 TetR-type HTH domain signature. 41 72 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site BWK49_RS28155 2c9711349ce03a5cc5d2bf02e70a37fc 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 42 3.4E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS28155 2c9711349ce03a5cc5d2bf02e70a37fc 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 50 73 3.4E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS28155 2c9711349ce03a5cc5d2bf02e70a37fc 212 SUPERFAMILY SSF46689 18 93 3.84E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS28155 2c9711349ce03a5cc5d2bf02e70a37fc 212 Gene3D G3DSA:1.10.357.10 69 201 2.2E-27 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS04745 663b8608b00bc9da1bb631397179251d 399 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 249 397 2.5E-44 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS04745 663b8608b00bc9da1bb631397179251d 399 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 26 139 1.7E-23 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS04745 663b8608b00bc9da1bb631397179251d 399 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 356 375 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 BWK49_RS04745 663b8608b00bc9da1bb631397179251d 399 Gene3D G3DSA:1.20.140.10 238 397 1.6E-58 T 06-07-2017 BWK49_RS04745 663b8608b00bc9da1bb631397179251d 399 SUPERFAMILY SSF47203 248 397 2.42E-45 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS04745 663b8608b00bc9da1bb631397179251d 399 Gene3D G3DSA:2.40.110.10 143 237 6.0E-38 T 06-07-2017 BWK49_RS04745 663b8608b00bc9da1bb631397179251d 399 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 143 237 2.0E-23 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 BWK49_RS04745 663b8608b00bc9da1bb631397179251d 399 SUPERFAMILY SSF56645 22 261 2.75E-75 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS04745 663b8608b00bc9da1bb631397179251d 399 Gene3D G3DSA:1.10.540.10 21 141 7.0E-30 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS09220 6ab903a0da87a38e7283ba678461a5f9 224 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 2.6E-15 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 BWK49_RS09220 6ab903a0da87a38e7283ba678461a5f9 224 Pfam PF07729 FCD domain 86 205 4.0E-25 T 06-07-2017 IPR011711 GntR, C-terminal BWK49_RS09220 6ab903a0da87a38e7283ba678461a5f9 224 SUPERFAMILY SSF46785 5 78 8.94E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS09220 6ab903a0da87a38e7283ba678461a5f9 224 SUPERFAMILY SSF48008 81 206 5.23E-22 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal BWK49_RS09220 6ab903a0da87a38e7283ba678461a5f9 224 Gene3D G3DSA:1.10.10.10 6 74 1.0E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS09220 6ab903a0da87a38e7283ba678461a5f9 224 SMART SM00895 84 206 6.3E-18 T 06-07-2017 IPR011711 GntR, C-terminal BWK49_RS09220 6ab903a0da87a38e7283ba678461a5f9 224 Gene3D G3DSA:1.20.120.530 80 207 8.5E-23 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal BWK49_RS09220 6ab903a0da87a38e7283ba678461a5f9 224 SMART SM00345 16 74 1.7E-11 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 BWK49_RS05900 559fe1bce4fa804e249da0bee783ce82 287 PRINTS PR00111 Alpha/beta hydrolase fold signature 108 121 6.7E-8 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS05900 559fe1bce4fa804e249da0bee783ce82 287 PRINTS PR00111 Alpha/beta hydrolase fold signature 230 244 6.7E-8 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS05900 559fe1bce4fa804e249da0bee783ce82 287 PRINTS PR00111 Alpha/beta hydrolase fold signature 64 79 6.7E-8 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS05900 559fe1bce4fa804e249da0bee783ce82 287 PRINTS PR00111 Alpha/beta hydrolase fold signature 122 135 6.7E-8 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS05900 559fe1bce4fa804e249da0bee783ce82 287 Pfam PF12697 Alpha/beta hydrolase family 41 277 5.3E-19 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS05900 559fe1bce4fa804e249da0bee783ce82 287 SUPERFAMILY SSF53474 15 284 1.61E-54 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS05900 559fe1bce4fa804e249da0bee783ce82 287 Gene3D G3DSA:3.40.50.1820 15 284 8.8E-56 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS00280 10d89527ed90afd90f50c6dfd8366b2d 249 Pfam PF00005 ABC transporter 28 174 2.0E-36 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 BWK49_RS00280 10d89527ed90afd90f50c6dfd8366b2d 249 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 BWK49_RS00280 10d89527ed90afd90f50c6dfd8366b2d 249 Gene3D G3DSA:3.40.50.300 13 245 1.2E-80 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS00280 10d89527ed90afd90f50c6dfd8366b2d 249 SUPERFAMILY SSF52540 16 244 6.53E-73 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS00280 10d89527ed90afd90f50c6dfd8366b2d 249 SMART SM00382 37 222 8.0E-18 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS00280 10d89527ed90afd90f50c6dfd8366b2d 249 PIRSF PIRSF039085 10 249 1.7E-95 T 06-07-2017 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 BWK49_RS08715 73b96b555df55ce85bb7772288f85b83 163 SMART SM00986 10 162 4.1E-5 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 BWK49_RS08715 73b96b555df55ce85bb7772288f85b83 163 Pfam PF03167 Uracil DNA glycosylase superfamily 11 159 4.3E-7 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 BWK49_RS08715 73b96b555df55ce85bb7772288f85b83 163 SMART SM00987 10 162 4.1E-5 T 06-07-2017 BWK49_RS08715 73b96b555df55ce85bb7772288f85b83 163 SUPERFAMILY SSF52141 8 161 2.88E-34 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 BWK49_RS08715 73b96b555df55ce85bb7772288f85b83 163 TIGRFAM TIGR04274 hypoxanDNAglyco: DNA-deoxyinosine glycosylase 8 158 3.4E-45 T 06-07-2017 IPR026353 Hypoxanthine-DNA glycosylase BWK49_RS08715 73b96b555df55ce85bb7772288f85b83 163 Gene3D G3DSA:3.40.470.10 9 161 2.6E-27 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 BWK49_RS07815 d3a6300e116c3c33fc8f0efbc372f7b2 484 Pfam PF00672 HAMP domain 209 275 3.5E-10 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 BWK49_RS07815 d3a6300e116c3c33fc8f0efbc372f7b2 484 Gene3D G3DSA:3.30.70.1230 310 475 1.3E-31 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 BWK49_RS07815 d3a6300e116c3c33fc8f0efbc372f7b2 484 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 310 474 2.3E-20 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 BWK49_RS07815 d3a6300e116c3c33fc8f0efbc372f7b2 484 SUPERFAMILY SSF158472 228 277 6.93E-6 T 06-07-2017 BWK49_RS07815 d3a6300e116c3c33fc8f0efbc372f7b2 484 SUPERFAMILY SSF55073 305 479 2.98E-46 T 06-07-2017 IPR029787 Nucleotide cyclase BWK49_RS07815 d3a6300e116c3c33fc8f0efbc372f7b2 484 SMART SM00044 276 464 3.6E-17 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 BWK49_RS07815 d3a6300e116c3c33fc8f0efbc372f7b2 484 SMART SM00304 228 280 1.8E-5 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 BWK49_RS12455 c8d6fb218b3ec597aab43f670552c0eb 416 Gene3D G3DSA:3.40.47.10 13 264 1.0E-54 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS12455 c8d6fb218b3ec597aab43f670552c0eb 416 SUPERFAMILY SSF53901 222 416 3.24E-61 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS12455 c8d6fb218b3ec597aab43f670552c0eb 416 SUPERFAMILY SSF53901 13 259 2.16E-58 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS12455 c8d6fb218b3ec597aab43f670552c0eb 416 SMART SM00825 Beta-ketoacyl synthase 14 407 5.3E-11 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain BWK49_RS12455 c8d6fb218b3ec597aab43f670552c0eb 416 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 262 373 1.2E-30 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal BWK49_RS12455 c8d6fb218b3ec597aab43f670552c0eb 416 Gene3D G3DSA:3.40.47.10 271 416 1.1E-50 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS12455 c8d6fb218b3ec597aab43f670552c0eb 416 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 13 253 5.0E-51 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal BWK49_RS04255 e1f9c9da1e3f9c87889d519ba9237989 296 Gene3D G3DSA:3.90.1530.10 40 141 1.2E-8 T 06-07-2017 BWK49_RS04255 e1f9c9da1e3f9c87889d519ba9237989 296 SMART SM00470 39 139 0.0089 T 06-07-2017 IPR003115 ParB/Sulfiredoxin BWK49_RS04255 e1f9c9da1e3f9c87889d519ba9237989 296 SUPERFAMILY SSF109709 135 226 2.75E-16 T 06-07-2017 BWK49_RS04255 e1f9c9da1e3f9c87889d519ba9237989 296 SUPERFAMILY SSF110849 41 141 4.36E-7 T 06-07-2017 IPR003115 ParB/Sulfiredoxin BWK49_RS27455 364355d48c1c3d4846184d57e1093f01 277 SUPERFAMILY SSF52799 7 276 4.32E-52 T 06-07-2017 IPR029021 Protein-tyrosine phosphatase-like BWK49_RS27455 364355d48c1c3d4846184d57e1093f01 277 Gene3D G3DSA:3.90.190.10 137 194 8.7E-17 T 06-07-2017 IPR029021 Protein-tyrosine phosphatase-like BWK49_RS27455 364355d48c1c3d4846184d57e1093f01 277 Gene3D G3DSA:3.90.190.10 8 89 8.7E-17 T 06-07-2017 IPR029021 Protein-tyrosine phosphatase-like BWK49_RS27455 364355d48c1c3d4846184d57e1093f01 277 Pfam PF13350 Tyrosine phosphatase family 7 276 1.6E-54 T 06-07-2017 IPR026893 Tyrosine/serine-protein phosphatase IphP-type BWK49_RS21930 b47c93f167f0eb558731c2d0a734ca59 332 TIGRFAM TIGR02823 oxido_YhdH: putative quinone oxidoreductase, YhdH/YhfP family 6 328 3.2E-125 T 06-07-2017 IPR014188 Acrylyl-CoA reductase AcuI BWK49_RS21930 b47c93f167f0eb558731c2d0a734ca59 332 Gene3D G3DSA:3.90.180.10 19 140 1.2E-11 T 06-07-2017 IPR011032 GroES-like BWK49_RS21930 b47c93f167f0eb558731c2d0a734ca59 332 SMART SM00829 18 326 8.5E-4 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 BWK49_RS21930 b47c93f167f0eb558731c2d0a734ca59 332 Pfam PF00107 Zinc-binding dehydrogenase 160 270 2.7E-13 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 BWK49_RS21930 b47c93f167f0eb558731c2d0a734ca59 332 Gene3D G3DSA:3.40.50.720 141 295 3.9E-64 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS21930 b47c93f167f0eb558731c2d0a734ca59 332 SUPERFAMILY SSF50129 4 145 8.33E-35 T 06-07-2017 IPR011032 GroES-like BWK49_RS21930 b47c93f167f0eb558731c2d0a734ca59 332 SUPERFAMILY SSF51735 118 289 3.64E-31 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS20855 b0f71fd71b11b6ddbdcf82b2b7bfdbac 315 SUPERFAMILY SSF55811 16 146 1.03E-26 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 BWK49_RS20855 b0f71fd71b11b6ddbdcf82b2b7bfdbac 315 ProSitePatterns PS00893 Nudix box signature. 55 76 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 BWK49_RS20855 b0f71fd71b11b6ddbdcf82b2b7bfdbac 315 PRINTS PR00502 NUDIX hydrolase family signature 64 79 1.0E-5 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 BWK49_RS20855 b0f71fd71b11b6ddbdcf82b2b7bfdbac 315 PRINTS PR00502 NUDIX hydrolase family signature 50 64 1.0E-5 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 BWK49_RS20855 b0f71fd71b11b6ddbdcf82b2b7bfdbac 315 Gene3D G3DSA:3.90.79.10 13 145 2.8E-29 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 BWK49_RS20855 b0f71fd71b11b6ddbdcf82b2b7bfdbac 315 SUPERFAMILY SSF53254 152 300 7.92E-21 T 06-07-2017 IPR029033 Histidine phosphatase superfamily BWK49_RS20855 b0f71fd71b11b6ddbdcf82b2b7bfdbac 315 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 155 234 4.1E-12 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 BWK49_RS20855 b0f71fd71b11b6ddbdcf82b2b7bfdbac 315 SMART SM00855 153 267 1.4E-9 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 BWK49_RS20855 b0f71fd71b11b6ddbdcf82b2b7bfdbac 315 Pfam PF00293 NUDIX domain 39 144 3.1E-16 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 BWK49_RS20855 b0f71fd71b11b6ddbdcf82b2b7bfdbac 315 Gene3D G3DSA:3.40.50.1240 153 296 3.6E-17 T 06-07-2017 IPR029033 Histidine phosphatase superfamily BWK49_RS22615 df11792d3f3e64bbb25077463950a37c 447 Gene3D G3DSA:3.90.1200.10 277 310 2.0E-5 T 06-07-2017 BWK49_RS22615 df11792d3f3e64bbb25077463950a37c 447 SUPERFAMILY SSF56112 100 163 1.71E-24 T 06-07-2017 IPR011009 Protein kinase-like domain BWK49_RS22615 df11792d3f3e64bbb25077463950a37c 447 SUPERFAMILY SSF56112 195 310 1.71E-24 T 06-07-2017 IPR011009 Protein kinase-like domain BWK49_RS22615 df11792d3f3e64bbb25077463950a37c 447 Pfam PF03109 ABC1 family 118 232 1.7E-33 T 06-07-2017 IPR004147 UbiB domain BWK49_RS22615 df11792d3f3e64bbb25077463950a37c 447 Gene3D G3DSA:3.30.200.20 137 171 8.0E-4 T 06-07-2017 BWK49_RS19745 c3a60202c51f9b637a97a45c65d77e3b 245 SUPERFAMILY SSF55347 106 214 1.77E-40 T 06-07-2017 BWK49_RS19745 c3a60202c51f9b637a97a45c65d77e3b 245 PIRSF PIRSF000161 1 245 4.7E-60 T 06-07-2017 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 BWK49_RS19745 c3a60202c51f9b637a97a45c65d77e3b 245 Gene3D G3DSA:3.40.50.720 1 121 1.9E-39 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS19745 c3a60202c51f9b637a97a45c65d77e3b 245 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 1 243 28.516 T 06-07-2017 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 BWK49_RS19745 c3a60202c51f9b637a97a45c65d77e3b 245 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 127 144 - T 06-07-2017 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 BWK49_RS19745 c3a60202c51f9b637a97a45c65d77e3b 245 Gene3D G3DSA:3.30.360.10 122 211 7.2E-33 T 06-07-2017 BWK49_RS19745 c3a60202c51f9b637a97a45c65d77e3b 245 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 1 105 2.4E-22 T 06-07-2017 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 BWK49_RS19745 c3a60202c51f9b637a97a45c65d77e3b 245 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 108 235 5.9E-30 T 06-07-2017 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 BWK49_RS19745 c3a60202c51f9b637a97a45c65d77e3b 245 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 46 242 7.6E-55 T 06-07-2017 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 BWK49_RS19745 c3a60202c51f9b637a97a45c65d77e3b 245 SUPERFAMILY SSF51735 1 132 6.46E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS28760 8dd3664f58e47236643f2529dd75f7cb 428 Gene3D G3DSA:3.40.1360.10 203 291 4.8E-4 T 06-07-2017 BWK49_RS28760 8dd3664f58e47236643f2529dd75f7cb 428 Gene3D G3DSA:3.90.580.10 19 80 5.8E-5 T 06-07-2017 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 BWK49_RS18945 a77a6c8f859a8d8b3b7cae64327fb751 166 Pfam PF09348 Domain of unknown function (DUF1990) 12 165 2.6E-57 T 06-07-2017 IPR018960 Domain of unknown function DUF1990 BWK49_RS18945 a77a6c8f859a8d8b3b7cae64327fb751 166 PIRSF PIRSF010260 2 166 3.4E-61 T 06-07-2017 IPR014457 Uncharacterised conserved protein UCP010260 BWK49_RS19205 716de7f2f2d404a2decb99fac9092805 276 TIGRFAM TIGR03971 SDR_subfam_1: SDR family mycofactocin-dependent oxidoreductase 4 274 2.4E-105 T 06-07-2017 IPR023985 Mycofactocin-dependent oxidoreductase BWK49_RS19205 716de7f2f2d404a2decb99fac9092805 276 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 272 9.2E-47 T 06-07-2017 BWK49_RS19205 716de7f2f2d404a2decb99fac9092805 276 SUPERFAMILY SSF51735 2 273 7.56E-63 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS19205 716de7f2f2d404a2decb99fac9092805 276 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 159 6.4E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS19205 716de7f2f2d404a2decb99fac9092805 276 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 94 105 6.4E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS19205 716de7f2f2d404a2decb99fac9092805 276 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 175 194 6.4E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS19205 716de7f2f2d404a2decb99fac9092805 276 Gene3D G3DSA:3.40.50.720 3 273 7.2E-71 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS19205 716de7f2f2d404a2decb99fac9092805 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 94 105 6.7E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS19205 716de7f2f2d404a2decb99fac9092805 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 196 213 6.7E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS19205 716de7f2f2d404a2decb99fac9092805 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 194 6.7E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS19205 716de7f2f2d404a2decb99fac9092805 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 236 256 6.7E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS19205 716de7f2f2d404a2decb99fac9092805 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 6.7E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS19205 716de7f2f2d404a2decb99fac9092805 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 161 6.7E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS19205 716de7f2f2d404a2decb99fac9092805 276 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 162 190 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS01685 ff1c358651849b2208379adece06e989 403 Gene3D G3DSA:3.50.50.60 108 308 4.4E-40 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS01685 ff1c358651849b2208379adece06e989 403 Gene3D G3DSA:3.50.50.60 2 107 7.1E-28 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS01685 ff1c358651849b2208379adece06e989 403 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 4.4E-18 T 06-07-2017 BWK49_RS01685 ff1c358651849b2208379adece06e989 403 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 255 277 4.4E-18 T 06-07-2017 BWK49_RS01685 ff1c358651849b2208379adece06e989 403 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 144 162 4.4E-18 T 06-07-2017 BWK49_RS01685 ff1c358651849b2208379adece06e989 403 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 229 245 4.4E-18 T 06-07-2017 BWK49_RS01685 ff1c358651849b2208379adece06e989 403 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 101 119 4.4E-18 T 06-07-2017 BWK49_RS01685 ff1c358651849b2208379adece06e989 403 SUPERFAMILY SSF51905 2 189 1.02E-37 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS01685 ff1c358651849b2208379adece06e989 403 Gene3D G3DSA:3.30.390.30 321 391 1.1E-14 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 BWK49_RS01685 ff1c358651849b2208379adece06e989 403 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 230 244 7.8E-16 T 06-07-2017 BWK49_RS01685 ff1c358651849b2208379adece06e989 403 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 7.8E-16 T 06-07-2017 BWK49_RS01685 ff1c358651849b2208379adece06e989 403 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 144 169 7.8E-16 T 06-07-2017 BWK49_RS01685 ff1c358651849b2208379adece06e989 403 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 270 277 7.8E-16 T 06-07-2017 BWK49_RS01685 ff1c358651849b2208379adece06e989 403 Pfam PF14759 Reductase C-terminal 321 390 6.6E-11 T 06-07-2017 IPR028202 Reductase, C-terminal BWK49_RS01685 ff1c358651849b2208379adece06e989 403 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 300 1.6E-56 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS01685 ff1c358651849b2208379adece06e989 403 SUPERFAMILY SSF51905 144 308 3.69E-27 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS01685 ff1c358651849b2208379adece06e989 403 SUPERFAMILY SSF55424 314 391 2.33E-14 T 06-07-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 BWK49_RS07560 0a13c62710cec19fa1c815373c793d61 556 Hamap MF_00275 Potassium-transporting ATPase potassium-binding subunit [kdpA]. 4 556 32.284 T 06-07-2017 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 BWK49_RS07560 0a13c62710cec19fa1c815373c793d61 556 Pfam PF03814 Potassium-transporting ATPase A subunit 13 554 3.0E-226 T 06-07-2017 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 BWK49_RS07560 0a13c62710cec19fa1c815373c793d61 556 TIGRFAM TIGR00680 kdpA: K+-transporting ATPase, A subunit 7 554 8.5E-206 T 06-07-2017 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 BWK49_RS07560 0a13c62710cec19fa1c815373c793d61 556 PIRSF PIRSF001294 3 556 2.2E-220 T 06-07-2017 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 BWK49_RS23570 d20cc6877fd1339b8a948a997e1db574 187 Pfam PF13599 Pentapeptide repeats (9 copies) 49 122 3.7E-13 T 06-07-2017 IPR001646 Pentapeptide repeat BWK49_RS23570 d20cc6877fd1339b8a948a997e1db574 187 SUPERFAMILY SSF141571 4 179 4.81E-45 T 06-07-2017 BWK49_RS08545 3cf407e9ddf53f926d275daceadca532 384 SUPERFAMILY SSF117916 14 103 1.63E-20 T 06-07-2017 BWK49_RS08545 3cf407e9ddf53f926d275daceadca532 384 Pfam PF01883 Domain of unknown function DUF59 14 86 3.1E-18 T 06-07-2017 IPR002744 Domain of unknown function DUF59 BWK49_RS08545 3cf407e9ddf53f926d275daceadca532 384 Gene3D G3DSA:3.40.50.300 112 364 2.6E-83 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS08545 3cf407e9ddf53f926d275daceadca532 384 ProSitePatterns PS01215 Mrp family signature. 224 240 - T 06-07-2017 IPR000808 Mrp, conserved site GO:0005524 BWK49_RS08545 3cf407e9ddf53f926d275daceadca532 384 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 120 365 8.5E-87 T 06-07-2017 IPR019591 Mrp/NBP35 ATP-binding protein BWK49_RS08545 3cf407e9ddf53f926d275daceadca532 384 SUPERFAMILY SSF52540 120 369 3.99E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS08545 3cf407e9ddf53f926d275daceadca532 384 Hamap MF_02040 Iron-sulfur cluster carrier protein. 114 366 33.225 T 06-07-2017 IPR019591 Mrp/NBP35 ATP-binding protein BWK49_RS17705 279f937ed9fe6b3494659e1e8f55fe48 303 Gene3D G3DSA:3.90.550.10 14 177 3.7E-6 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases BWK49_RS17705 279f937ed9fe6b3494659e1e8f55fe48 303 SUPERFAMILY SSF53448 5 236 1.97E-26 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases BWK49_RS23125 da59963b2854a494ae6dd3dfebfdb227 397 SMART SM00331 176 394 2.1E-18 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 BWK49_RS23125 da59963b2854a494ae6dd3dfebfdb227 397 Gene3D G3DSA:3.40.50.2300 17 140 1.2E-26 T 06-07-2017 BWK49_RS23125 da59963b2854a494ae6dd3dfebfdb227 397 Pfam PF00072 Response regulator receiver domain 20 127 2.2E-17 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 BWK49_RS23125 da59963b2854a494ae6dd3dfebfdb227 397 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 203 394 9.3E-32 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 BWK49_RS23125 da59963b2854a494ae6dd3dfebfdb227 397 SUPERFAMILY SSF52172 15 141 3.84E-27 T 06-07-2017 IPR011006 CheY-like superfamily BWK49_RS23125 da59963b2854a494ae6dd3dfebfdb227 397 SMART SM00448 17 130 3.5E-16 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 BWK49_RS12040 870da49bf40afbcc85e4d7f09a142f62 242 Pfam PF00459 Inositol monophosphatase family 160 225 3.4E-10 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 BWK49_RS12040 870da49bf40afbcc85e4d7f09a142f62 242 Pfam PF00459 Inositol monophosphatase family 7 122 1.9E-19 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 BWK49_RS12040 870da49bf40afbcc85e4d7f09a142f62 242 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 76 88 - T 06-07-2017 IPR020583 Inositol monophosphatase, metal-binding site BWK49_RS12040 870da49bf40afbcc85e4d7f09a142f62 242 SUPERFAMILY SSF56655 2 239 4.84E-52 T 06-07-2017 BWK49_RS12040 870da49bf40afbcc85e4d7f09a142f62 242 Gene3D G3DSA:3.30.540.10 4 122 7.3E-26 T 06-07-2017 BWK49_RS12040 870da49bf40afbcc85e4d7f09a142f62 242 Gene3D G3DSA:3.40.190.80 129 239 6.5E-25 T 06-07-2017 BWK49_RS15575 86439f814e4315f99861b8e0d7d6ed49 279 Pfam PF01261 Xylose isomerase-like TIM barrel 27 226 8.2E-13 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain BWK49_RS15575 86439f814e4315f99861b8e0d7d6ed49 279 SUPERFAMILY SSF51658 9 276 2.34E-47 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain BWK49_RS15575 86439f814e4315f99861b8e0d7d6ed49 279 Gene3D G3DSA:3.20.20.150 7 261 5.4E-40 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain BWK49_RS25715 0d9a8894f08991aeca3de97887531d2b 376 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 21 297 2.8E-85 T 06-07-2017 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 BWK49_RS25715 0d9a8894f08991aeca3de97887531d2b 376 SUPERFAMILY SSF55931 10 374 1.08E-114 T 06-07-2017 BWK49_RS25715 0d9a8894f08991aeca3de97887531d2b 376 TIGRFAM TIGR02050 gshA_cyan_rel: carboxylate-amine ligase, YbdK family 19 302 1.2E-114 T 06-07-2017 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 BWK49_RS25715 0d9a8894f08991aeca3de97887531d2b 376 Hamap MF_01609 Glutamate--cysteine ligase [gshA]. 1 376 104.233 T 06-07-2017 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 BWK49_RS12080 6c95e75a10f681ec209724976bb694b2 364 Gene3D G3DSA:3.40.50.720 6 145 6.1E-23 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS12080 6c95e75a10f681ec209724976bb694b2 364 SUPERFAMILY SSF51735 4 163 1.76E-15 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS07445 37acd66ce1e7697dade69058b992b8f5 289 Pfam PF00106 short chain dehydrogenase 16 206 7.4E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS07445 37acd66ce1e7697dade69058b992b8f5 289 SUPERFAMILY SSF51735 11 240 8.54E-52 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS07445 37acd66ce1e7697dade69058b992b8f5 289 Gene3D G3DSA:3.40.50.720 12 239 7.6E-54 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS07445 37acd66ce1e7697dade69058b992b8f5 289 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 3.1E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS07445 37acd66ce1e7697dade69058b992b8f5 289 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 163 182 3.1E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS07445 37acd66ce1e7697dade69058b992b8f5 289 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 3.1E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS07445 37acd66ce1e7697dade69058b992b8f5 289 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 16 33 1.0E-16 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS07445 37acd66ce1e7697dade69058b992b8f5 289 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 186 203 1.0E-16 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS07445 37acd66ce1e7697dade69058b992b8f5 289 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 1.0E-16 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS07445 37acd66ce1e7697dade69058b992b8f5 289 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 1.0E-16 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS07445 37acd66ce1e7697dade69058b992b8f5 289 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 182 1.0E-16 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS06920 3e65bd347c73d9589fdf4a488bf77160 254 SUPERFAMILY SSF52091 13 122 1.75E-12 T 06-07-2017 IPR002645 STAS domain BWK49_RS06920 3e65bd347c73d9589fdf4a488bf77160 254 Pfam PF01740 STAS domain 14 113 3.3E-7 T 06-07-2017 IPR002645 STAS domain BWK49_RS06920 3e65bd347c73d9589fdf4a488bf77160 254 Gene3D G3DSA:3.30.750.24 11 122 3.1E-12 T 06-07-2017 IPR002645 STAS domain BWK49_RS00415 d36e4b01194473d9a4d427b625d60f6f 405 Gene3D G3DSA:1.20.1640.10 151 354 4.3E-26 T 06-07-2017 BWK49_RS00415 d36e4b01194473d9a4d427b625d60f6f 405 Pfam PF03176 MMPL family 53 382 5.4E-97 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 BWK49_RS00415 d36e4b01194473d9a4d427b625d60f6f 405 SUPERFAMILY SSF82866 151 349 7.06E-25 T 06-07-2017 BWK49_RS21135 ab5cbf60b31bae7dc0e3d7389d1aba64 506 Pfam PF01593 Flavin containing amine oxidoreductase 18 488 1.1E-41 T 06-07-2017 IPR002937 Amine oxidase GO:0016491|GO:0055114 BWK49_RS21135 ab5cbf60b31bae7dc0e3d7389d1aba64 506 TIGRFAM TIGR02734 crtI_fam: phytoene desaturase 11 494 2.3E-158 T 06-07-2017 IPR014105 Carotenoid/retinoid oxidoreductase GO:0016117|GO:0055114 BWK49_RS21135 ab5cbf60b31bae7dc0e3d7389d1aba64 506 Gene3D G3DSA:3.50.50.60 11 101 9.7E-35 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS21135 ab5cbf60b31bae7dc0e3d7389d1aba64 506 Gene3D G3DSA:3.50.50.60 135 136 9.7E-35 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS21135 ab5cbf60b31bae7dc0e3d7389d1aba64 506 Gene3D G3DSA:3.50.50.60 219 353 9.7E-35 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS21135 ab5cbf60b31bae7dc0e3d7389d1aba64 506 SUPERFAMILY SSF51905 10 319 3.89E-61 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS21135 ab5cbf60b31bae7dc0e3d7389d1aba64 506 SUPERFAMILY SSF51905 450 489 3.89E-61 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS28405 bb5c4b30fdc0ee8c5a3454db68bc4196 102 Gene3D G3DSA:3.10.310.10 57 102 6.2E-7 T 06-07-2017 BWK49_RS28405 bb5c4b30fdc0ee8c5a3454db68bc4196 102 SUPERFAMILY SSF54506 37 102 3.81E-7 T 06-07-2017 BWK49_RS10215 b0fd789f19dd4689eb22522b821b426f 144 Pfam PF14032 PknH-like extracellular domain 26 142 2.4E-18 T 06-07-2017 IPR026954 PknH-like extracellular domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 BWK49_RS03460 866a4fbcc0dd9a6b9e7f7bb5c564680d 352 TIGRFAM TIGR03217 4OH_2_O_val_ald: 4-hydroxy-2-oxovalerate aldolase 13 343 8.5E-154 T 06-07-2017 IPR017629 4-hydroxy-2-oxovalerate aldolase GO:0008701|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 BWK49_RS03460 866a4fbcc0dd9a6b9e7f7bb5c564680d 352 Pfam PF07836 DmpG-like communication domain 281 341 2.0E-27 T 06-07-2017 IPR012425 DmpG-like communication GO:0016833|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 BWK49_RS03460 866a4fbcc0dd9a6b9e7f7bb5c564680d 352 SUPERFAMILY SSF89000 295 344 3.92E-16 T 06-07-2017 BWK49_RS03460 866a4fbcc0dd9a6b9e7f7bb5c564680d 352 ProDom PD005364 ALDOLASE 4-HYDROXY-2-OXOVALERATE LYASE PYRUVATE 4.1.3.- PLASMID HMG-COA LYASE-LIKE TRANSFERASE HOA 282 340 6.0E-26 T 06-07-2017 IPR012425 DmpG-like communication GO:0016833|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 BWK49_RS03460 866a4fbcc0dd9a6b9e7f7bb5c564680d 352 Gene3D G3DSA:1.10.8.60 283 346 2.5E-28 T 06-07-2017 BWK49_RS03460 866a4fbcc0dd9a6b9e7f7bb5c564680d 352 Gene3D G3DSA:3.20.20.70 13 269 2.9E-48 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 BWK49_RS03460 866a4fbcc0dd9a6b9e7f7bb5c564680d 352 Pfam PF00682 HMGL-like 13 270 6.8E-49 T 06-07-2017 IPR000891 Pyruvate carboxyltransferase GO:0003824 BWK49_RS03460 866a4fbcc0dd9a6b9e7f7bb5c564680d 352 SUPERFAMILY SSF51569 12 273 2.93E-57 T 06-07-2017 BWK49_RS03460 866a4fbcc0dd9a6b9e7f7bb5c564680d 352 Hamap MF_01656 4-hydroxy-2-oxovalerate aldolase [mhpE]. 1 349 174.039 T 06-07-2017 IPR017629 4-hydroxy-2-oxovalerate aldolase GO:0008701|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 BWK49_RS03265 58e6f94c076574bb4250982f1164b5c0 364 PRINTS PR00410 Phenol hydroxylase reductase family signature 120 129 4.7E-9 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 BWK49_RS03265 58e6f94c076574bb4250982f1164b5c0 364 PRINTS PR00410 Phenol hydroxylase reductase family signature 56 68 4.7E-9 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 BWK49_RS03265 58e6f94c076574bb4250982f1164b5c0 364 PRINTS PR00410 Phenol hydroxylase reductase family signature 135 154 4.7E-9 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 BWK49_RS03265 58e6f94c076574bb4250982f1164b5c0 364 PRINTS PR00410 Phenol hydroxylase reductase family signature 219 227 4.7E-9 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 BWK49_RS03265 58e6f94c076574bb4250982f1164b5c0 364 Gene3D G3DSA:3.40.50.80 118 245 2.9E-29 T 06-07-2017 BWK49_RS03265 58e6f94c076574bb4250982f1164b5c0 364 SUPERFAMILY SSF54292 242 360 6.55E-26 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 BWK49_RS03265 58e6f94c076574bb4250982f1164b5c0 364 Gene3D G3DSA:2.40.30.10 19 117 2.6E-24 T 06-07-2017 BWK49_RS03265 58e6f94c076574bb4250982f1164b5c0 364 Pfam PF00175 Oxidoreductase NAD-binding domain 136 233 2.8E-14 T 06-07-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 BWK49_RS03265 58e6f94c076574bb4250982f1164b5c0 364 SUPERFAMILY SSF63380 18 125 2.32E-21 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 BWK49_RS03265 58e6f94c076574bb4250982f1164b5c0 364 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 311 319 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 BWK49_RS03265 58e6f94c076574bb4250982f1164b5c0 364 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 135 154 1.3E-7 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 BWK49_RS03265 58e6f94c076574bb4250982f1164b5c0 364 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 76 83 1.3E-7 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 BWK49_RS03265 58e6f94c076574bb4250982f1164b5c0 364 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 159 168 1.3E-7 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 BWK49_RS03265 58e6f94c076574bb4250982f1164b5c0 364 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 219 227 1.3E-7 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 BWK49_RS03265 58e6f94c076574bb4250982f1164b5c0 364 Pfam PF00970 Oxidoreductase FAD-binding domain 24 125 1.8E-8 T 06-07-2017 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 BWK49_RS03265 58e6f94c076574bb4250982f1164b5c0 364 Gene3D G3DSA:3.10.20.30 246 363 3.8E-31 T 06-07-2017 IPR012675 Beta-grasp domain BWK49_RS03265 58e6f94c076574bb4250982f1164b5c0 364 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 280 353 7.4E-14 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 BWK49_RS03265 58e6f94c076574bb4250982f1164b5c0 364 SUPERFAMILY SSF52343 117 249 4.58E-31 T 06-07-2017 BWK49_RS00635 af278f5d8bf07cb1010dfd26b89db851 263 Pfam PF12151 Mannan-binding protein 24 59 2.8E-14 T 06-07-2017 IPR021992 Mannan-binding protein BWK49_RS00635 af278f5d8bf07cb1010dfd26b89db851 263 Pfam PF11738 Protein of unknown function (DUF3298) 149 227 1.8E-7 T 06-07-2017 IPR021729 Domain of unknown function DUF3298 BWK49_RS05370 cbb0a5905a7533baf00bf9a5103f1582 252 Pfam PF00106 short chain dehydrogenase 8 200 6.0E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05370 cbb0a5905a7533baf00bf9a5103f1582 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 5.2E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05370 cbb0a5905a7533baf00bf9a5103f1582 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 5.2E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05370 cbb0a5905a7533baf00bf9a5103f1582 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 5.2E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05370 cbb0a5905a7533baf00bf9a5103f1582 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 5.2E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05370 cbb0a5905a7533baf00bf9a5103f1582 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 5.2E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05370 cbb0a5905a7533baf00bf9a5103f1582 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 5.2E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05370 cbb0a5905a7533baf00bf9a5103f1582 252 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 189 0.0027 T 06-07-2017 BWK49_RS05370 cbb0a5905a7533baf00bf9a5103f1582 252 SUPERFAMILY SSF51735 8 247 3.17E-54 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS05370 cbb0a5905a7533baf00bf9a5103f1582 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 1.4E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05370 cbb0a5905a7533baf00bf9a5103f1582 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 1.4E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05370 cbb0a5905a7533baf00bf9a5103f1582 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 1.4E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05370 cbb0a5905a7533baf00bf9a5103f1582 252 Gene3D G3DSA:3.40.50.720 6 248 7.3E-61 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS12510 99c179eac9bc6c39c85c9c9606810bcb 131 SUPERFAMILY SSF54593 5 130 1.38E-24 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS12510 99c179eac9bc6c39c85c9c9606810bcb 131 Gene3D G3DSA:3.10.180.10 8 128 1.3E-24 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS12510 99c179eac9bc6c39c85c9c9606810bcb 131 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 126 8.2E-14 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain BWK49_RS05065 8373e105ead1d13a43f9934dccaf19dc 497 Gene3D G3DSA:3.40.47.10 221 252 1.5E-8 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS05065 8373e105ead1d13a43f9934dccaf19dc 497 Gene3D G3DSA:3.40.47.10 25 115 1.5E-8 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS05065 8373e105ead1d13a43f9934dccaf19dc 497 SUPERFAMILY SSF53901 26 119 6.73E-14 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS05065 8373e105ead1d13a43f9934dccaf19dc 497 SUPERFAMILY SSF53901 204 381 6.73E-14 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS18950 dc365195e83e37377eecf308e94541d4 147 Pfam PF07681 DoxX 24 107 2.8E-6 T 06-07-2017 IPR032808 DoxX family BWK49_RS08145 e92ff84cc3af579fcdf983fbda500132 452 Gene3D G3DSA:3.40.50.720 6 231 7.7E-47 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS08145 e92ff84cc3af579fcdf983fbda500132 452 SUPERFAMILY SSF51735 7 239 1.98E-51 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS08145 e92ff84cc3af579fcdf983fbda500132 452 Pfam PF11066 Protein of unknown function (DUF2867) 371 439 9.5E-6 T 06-07-2017 IPR021295 Protein of unknown function DUF2867 BWK49_RS08145 e92ff84cc3af579fcdf983fbda500132 452 Pfam PF13460 NAD(P)H-binding 11 149 2.8E-25 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS20030 fbe7438872d454be110ccc9aa46303cf 454 SUPERFAMILY SSF53720 5 449 3.8E-148 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 BWK49_RS20030 fbe7438872d454be110ccc9aa46303cf 454 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 256 267 - T 06-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 BWK49_RS20030 fbe7438872d454be110ccc9aa46303cf 454 Gene3D G3DSA:3.40.309.10 243 427 9.6E-60 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 BWK49_RS20030 fbe7438872d454be110ccc9aa46303cf 454 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 228 235 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 BWK49_RS20030 fbe7438872d454be110ccc9aa46303cf 454 Gene3D G3DSA:3.40.605.10 5 242 5.2E-83 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 BWK49_RS20030 fbe7438872d454be110ccc9aa46303cf 454 Pfam PF00171 Aldehyde dehydrogenase family 5 447 6.4E-153 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 BWK49_RS21310 76daf085facbeb82b4ae7e7ec83e25f3 178 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 59 2.6E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS21310 76daf085facbeb82b4ae7e7ec83e25f3 178 Gene3D G3DSA:1.10.357.10 7 177 1.7E-24 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS21310 76daf085facbeb82b4ae7e7ec83e25f3 178 SUPERFAMILY SSF46689 3 77 3.23E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS01085 07f4bfb8a8b172a77081ec477c5921f2 518 Pfam PF13450 NAD(P)-binding Rossmann-like domain 8 63 3.1E-8 T 06-07-2017 BWK49_RS01085 07f4bfb8a8b172a77081ec477c5921f2 518 Gene3D G3DSA:3.50.50.60 229 321 1.8E-33 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS01085 07f4bfb8a8b172a77081ec477c5921f2 518 Gene3D G3DSA:3.50.50.60 2 119 1.8E-33 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS01085 07f4bfb8a8b172a77081ec477c5921f2 518 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 2.8E-5 T 06-07-2017 BWK49_RS01085 07f4bfb8a8b172a77081ec477c5921f2 518 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 259 273 2.8E-5 T 06-07-2017 BWK49_RS01085 07f4bfb8a8b172a77081ec477c5921f2 518 Pfam PF01593 Flavin containing amine oxidoreductase 220 331 3.2E-7 T 06-07-2017 IPR002937 Amine oxidase GO:0016491|GO:0055114 BWK49_RS01085 07f4bfb8a8b172a77081ec477c5921f2 518 SUPERFAMILY SSF51905 368 397 7.66E-40 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS01085 07f4bfb8a8b172a77081ec477c5921f2 518 SUPERFAMILY SSF51905 1 332 7.66E-40 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS11600 469a91e4cdf0bd32b3a61bb42d2d6c17 721 Pfam PF01061 ABC-2 type transporter 444 658 1.9E-11 T 06-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 BWK49_RS11600 469a91e4cdf0bd32b3a61bb42d2d6c17 721 SUPERFAMILY SSF52540 171 390 1.01E-31 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS11600 469a91e4cdf0bd32b3a61bb42d2d6c17 721 Gene3D G3DSA:3.40.50.300 169 389 9.6E-39 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS11600 469a91e4cdf0bd32b3a61bb42d2d6c17 721 Pfam PF00005 ABC transporter 182 329 1.8E-17 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 BWK49_RS09965 f2b65751419cb880cbe6bc9492cf37e0 882 PRINTS PR00986 Valyl-tRNA synthetase signature 356 369 4.6E-38 T 06-07-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 BWK49_RS09965 f2b65751419cb880cbe6bc9492cf37e0 882 PRINTS PR00986 Valyl-tRNA synthetase signature 448 469 4.6E-38 T 06-07-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 BWK49_RS09965 f2b65751419cb880cbe6bc9492cf37e0 882 PRINTS PR00986 Valyl-tRNA synthetase signature 240 257 4.6E-38 T 06-07-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 BWK49_RS09965 f2b65751419cb880cbe6bc9492cf37e0 882 PRINTS PR00986 Valyl-tRNA synthetase signature 45 56 4.6E-38 T 06-07-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 BWK49_RS09965 f2b65751419cb880cbe6bc9492cf37e0 882 PRINTS PR00986 Valyl-tRNA synthetase signature 479 497 4.6E-38 T 06-07-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 BWK49_RS09965 f2b65751419cb880cbe6bc9492cf37e0 882 SUPERFAMILY SSF52374 351 589 6.28E-131 T 06-07-2017 BWK49_RS09965 f2b65751419cb880cbe6bc9492cf37e0 882 SUPERFAMILY SSF52374 9 201 6.28E-131 T 06-07-2017 BWK49_RS09965 f2b65751419cb880cbe6bc9492cf37e0 882 Hamap MF_02004 Valine--tRNA ligase [valS]. 11 882 14.847 T 06-07-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 BWK49_RS09965 f2b65751419cb880cbe6bc9492cf37e0 882 Pfam PF08264 Anticodon-binding domain of tRNA 620 759 1.3E-38 T 06-07-2017 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 BWK49_RS09965 f2b65751419cb880cbe6bc9492cf37e0 882 SUPERFAMILY SSF47323 590 830 2.62E-49 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 BWK49_RS09965 f2b65751419cb880cbe6bc9492cf37e0 882 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 52 63 - T 06-07-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 BWK49_RS09965 f2b65751419cb880cbe6bc9492cf37e0 882 Gene3D G3DSA:1.10.287.380 812 881 2.4E-8 T 06-07-2017 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 BWK49_RS09965 f2b65751419cb880cbe6bc9492cf37e0 882 SUPERFAMILY SSF50677 202 345 2.22E-52 T 06-07-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 BWK49_RS09965 f2b65751419cb880cbe6bc9492cf37e0 882 SUPERFAMILY SSF46589 817 881 2.04E-13 T 06-07-2017 IPR010978 tRNA-binding arm GO:0000166 BWK49_RS09965 f2b65751419cb880cbe6bc9492cf37e0 882 Gene3D G3DSA:3.90.740.10 203 344 4.3E-44 T 06-07-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 BWK49_RS09965 f2b65751419cb880cbe6bc9492cf37e0 882 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 817 881 1.5E-16 T 06-07-2017 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 BWK49_RS09965 f2b65751419cb880cbe6bc9492cf37e0 882 TIGRFAM TIGR00422 valS: valine--tRNA ligase 12 860 1.6E-299 T 06-07-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 BWK49_RS09965 f2b65751419cb880cbe6bc9492cf37e0 882 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 444 577 2.2E-45 T 06-07-2017 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 BWK49_RS09965 f2b65751419cb880cbe6bc9492cf37e0 882 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 24 435 1.3E-144 T 06-07-2017 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 BWK49_RS09965 f2b65751419cb880cbe6bc9492cf37e0 882 Gene3D G3DSA:1.10.730.10 580 751 4.7E-55 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 BWK49_RS09965 f2b65751419cb880cbe6bc9492cf37e0 882 Gene3D G3DSA:3.40.50.620 13 202 9.9E-135 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold BWK49_RS09965 f2b65751419cb880cbe6bc9492cf37e0 882 Gene3D G3DSA:3.40.50.620 351 576 9.9E-135 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold BWK49_RS19725 1f00debf472b5ad646b0441497e0d420 508 Pfam PF13193 AMP-binding enzyme C-terminal domain 416 491 1.3E-12 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS19725 1f00debf472b5ad646b0441497e0d420 508 SUPERFAMILY SSF56801 27 501 1.57E-127 T 06-07-2017 BWK49_RS19725 1f00debf472b5ad646b0441497e0d420 508 Pfam PF00501 AMP-binding enzyme 151 407 6.4E-67 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS19725 1f00debf472b5ad646b0441497e0d420 508 Pfam PF00501 AMP-binding enzyme 38 130 8.8E-21 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS19725 1f00debf472b5ad646b0441497e0d420 508 ProSitePatterns PS00455 Putative AMP-binding domain signature. 159 170 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS19725 1f00debf472b5ad646b0441497e0d420 508 Gene3D G3DSA:3.40.50.980 169 323 7.6E-42 T 06-07-2017 BWK49_RS19725 1f00debf472b5ad646b0441497e0d420 508 Gene3D G3DSA:3.30.300.30 402 500 1.4E-24 T 06-07-2017 BWK49_RS19725 1f00debf472b5ad646b0441497e0d420 508 Gene3D G3DSA:2.30.38.10 329 400 9.2E-20 T 06-07-2017 BWK49_RS19725 1f00debf472b5ad646b0441497e0d420 508 Gene3D G3DSA:3.40.50.980 31 168 1.1E-32 T 06-07-2017 BWK49_RS21920 e8dafa03f15004e5d50cabb3fce8d16e 465 SUPERFAMILY SSF56645 101 324 1.1E-46 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS21920 e8dafa03f15004e5d50cabb3fce8d16e 465 Gene3D G3DSA:1.20.140.10 316 461 1.0E-38 T 06-07-2017 BWK49_RS21920 e8dafa03f15004e5d50cabb3fce8d16e 465 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 433 452 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 BWK49_RS21920 e8dafa03f15004e5d50cabb3fce8d16e 465 Gene3D G3DSA:1.10.540.10 99 218 1.0E-27 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS21920 e8dafa03f15004e5d50cabb3fce8d16e 465 Gene3D G3DSA:2.40.110.10 224 315 1.6E-17 T 06-07-2017 BWK49_RS21920 e8dafa03f15004e5d50cabb3fce8d16e 465 SUPERFAMILY SSF47203 336 462 7.09E-35 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS21920 e8dafa03f15004e5d50cabb3fce8d16e 465 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 225 313 1.0E-11 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 BWK49_RS21920 e8dafa03f15004e5d50cabb3fce8d16e 465 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 334 461 3.3E-27 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS21920 e8dafa03f15004e5d50cabb3fce8d16e 465 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 108 217 1.3E-23 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS04730 a2c1055f1837579d473ba119d182768f 129 SUPERFAMILY SSF50249 2 116 6.17E-35 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS04730 a2c1055f1837579d473ba119d182768f 129 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 49 112 1.9E-23 T 06-07-2017 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal BWK49_RS04730 a2c1055f1837579d473ba119d182768f 129 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 12 48 3.2E-10 T 06-07-2017 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal BWK49_RS22275 d439965b8e27911ec2466eafa851762b 393 SUPERFAMILY SSF51735 157 353 4.18E-43 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS22275 d439965b8e27911ec2466eafa851762b 393 Gene3D G3DSA:3.40.50.720 293 334 5.2E-33 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS22275 d439965b8e27911ec2466eafa851762b 393 Gene3D G3DSA:3.40.50.720 181 258 5.2E-33 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS22275 d439965b8e27911ec2466eafa851762b 393 Pfam PF00107 Zinc-binding dehydrogenase 189 258 2.2E-10 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 BWK49_RS22275 d439965b8e27911ec2466eafa851762b 393 Pfam PF13823 Alcohol dehydrogenase GroES-associated 1 23 8.9E-15 T 06-07-2017 IPR027399 Alcohol dehydrogenase GroES-associated BWK49_RS22275 d439965b8e27911ec2466eafa851762b 393 SUPERFAMILY SSF50129 1 188 4.72E-55 T 06-07-2017 IPR011032 GroES-like BWK49_RS22275 d439965b8e27911ec2466eafa851762b 393 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 143 2.6E-24 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 BWK49_RS22275 d439965b8e27911ec2466eafa851762b 393 Gene3D G3DSA:3.90.180.10 1 180 1.7E-43 T 06-07-2017 IPR011032 GroES-like BWK49_RS02485 82199481c7ce7fd0ea34a65d2ef2c9bd 241 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 29 230 3.0E-33 T 06-07-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 BWK49_RS02485 82199481c7ce7fd0ea34a65d2ef2c9bd 241 Gene3D G3DSA:3.40.630.40 26 234 2.6E-38 T 06-07-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 BWK49_RS02485 82199481c7ce7fd0ea34a65d2ef2c9bd 241 SUPERFAMILY SSF53187 26 234 1.19E-34 T 06-07-2017 BWK49_RS02485 82199481c7ce7fd0ea34a65d2ef2c9bd 241 SMART SM00646 110 231 9.1E-27 T 06-07-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 BWK49_RS02165 e7eda29b7eb6cbe6bfb75ca1214beee7 315 Gene3D G3DSA:3.40.190.120 146 247 6.0E-28 T 06-07-2017 BWK49_RS02165 e7eda29b7eb6cbe6bfb75ca1214beee7 315 SUPERFAMILY SSF53850 42 309 1.87E-48 T 06-07-2017 BWK49_RS02165 e7eda29b7eb6cbe6bfb75ca1214beee7 315 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 42 305 4.8E-50 T 06-07-2017 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 BWK49_RS02165 e7eda29b7eb6cbe6bfb75ca1214beee7 315 Gene3D G3DSA:3.40.190.10 259 309 5.2E-37 T 06-07-2017 BWK49_RS02165 e7eda29b7eb6cbe6bfb75ca1214beee7 315 Gene3D G3DSA:3.40.190.10 39 145 5.2E-37 T 06-07-2017 BWK49_RS03015 9a1e26d9573864653c29d5fac6776ea1 99 SUPERFAMILY SSF140459 8 84 1.65E-19 T 06-07-2017 BWK49_RS03015 9a1e26d9573864653c29d5fac6776ea1 99 Pfam PF00934 PE family 1 92 3.7E-27 T 06-07-2017 IPR000084 PE-PGRS family, N-terminal BWK49_RS18045 efa21f6516fe2ad6c2a42900b9d81ffd 306 Pfam PF13602 Zinc-binding dehydrogenase 188 290 1.1E-14 T 06-07-2017 BWK49_RS18045 efa21f6516fe2ad6c2a42900b9d81ffd 306 SMART SM00829 12 301 1.1E-14 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 BWK49_RS18045 efa21f6516fe2ad6c2a42900b9d81ffd 306 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 146 167 - T 06-07-2017 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 BWK49_RS18045 efa21f6516fe2ad6c2a42900b9d81ffd 306 Gene3D G3DSA:3.90.180.10 1 152 2.5E-37 T 06-07-2017 IPR011032 GroES-like BWK49_RS18045 efa21f6516fe2ad6c2a42900b9d81ffd 306 SUPERFAMILY SSF50129 12 151 1.21E-29 T 06-07-2017 IPR011032 GroES-like BWK49_RS18045 efa21f6516fe2ad6c2a42900b9d81ffd 306 SUPERFAMILY SSF51735 118 244 2.8E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS18045 efa21f6516fe2ad6c2a42900b9d81ffd 306 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 89 7.5E-8 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 BWK49_RS18045 efa21f6516fe2ad6c2a42900b9d81ffd 306 Gene3D G3DSA:3.40.50.720 153 242 4.6E-19 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS09960 30f1240ef957667d3b15d47325528e8b 419 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 10 137 1.2E-14 T 06-07-2017 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 BWK49_RS09960 30f1240ef957667d3b15d47325528e8b 419 Gene3D G3DSA:3.40.50.720 10 164 1.4E-19 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS09960 30f1240ef957667d3b15d47325528e8b 419 SUPERFAMILY SSF51735 10 166 3.64E-16 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS08940 46d18355dfc6de9058945ed8f0c109ff 252 ProSitePatterns PS00449 ATP synthase a subunit signature. 184 193 - T 06-07-2017 IPR023011 ATPase, F0 complex, subunit A, active site Reactome: R-HSA-163210 BWK49_RS08940 46d18355dfc6de9058945ed8f0c109ff 252 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 33 244 1.8E-37 T 06-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 BWK49_RS08940 46d18355dfc6de9058945ed8f0c109ff 252 SUPERFAMILY SSF81336 87 242 1.1E-35 T 06-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 BWK49_RS08940 46d18355dfc6de9058945ed8f0c109ff 252 Pfam PF00119 ATP synthase A chain 34 242 2.2E-49 T 06-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 BWK49_RS08940 46d18355dfc6de9058945ed8f0c109ff 252 PRINTS PR00123 ATP synthase A subunit signature 181 203 4.5E-20 T 06-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 BWK49_RS08940 46d18355dfc6de9058945ed8f0c109ff 252 PRINTS PR00123 ATP synthase A subunit signature 92 108 4.5E-20 T 06-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 BWK49_RS08940 46d18355dfc6de9058945ed8f0c109ff 252 PRINTS PR00123 ATP synthase A subunit signature 228 243 4.5E-20 T 06-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 BWK49_RS08940 46d18355dfc6de9058945ed8f0c109ff 252 PRINTS PR00123 ATP synthase A subunit signature 165 180 4.5E-20 T 06-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 BWK49_RS08940 46d18355dfc6de9058945ed8f0c109ff 252 Gene3D G3DSA:1.20.120.220 89 246 7.0E-42 T 06-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 BWK49_RS08940 46d18355dfc6de9058945ed8f0c109ff 252 Hamap MF_01393 ATP synthase subunit a [atpB]. 15 248 13.576 T 06-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 BWK49_RS23530 7f60543453fc4c5f2be0cf54fe58ca80 144 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 122 5.6E-10 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain BWK49_RS23530 7f60543453fc4c5f2be0cf54fe58ca80 144 Gene3D G3DSA:3.10.180.10 1 139 2.6E-37 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS23530 7f60543453fc4c5f2be0cf54fe58ca80 144 SUPERFAMILY SSF54593 3 132 2.75E-27 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS18800 38dcdc9b3fd6622a2fe91a390f789a0a 108 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 3 84 5.3E-27 T 06-07-2017 IPR003849 Preprotein translocase YajC BWK49_RS18800 38dcdc9b3fd6622a2fe91a390f789a0a 108 SMART SM01323 2 84 6.5E-27 T 06-07-2017 IPR003849 Preprotein translocase YajC BWK49_RS18800 38dcdc9b3fd6622a2fe91a390f789a0a 108 Pfam PF02699 Preprotein translocase subunit 7 81 2.8E-17 T 06-07-2017 IPR003849 Preprotein translocase YajC BWK49_RS27300 6718cb0da8bb43b6ffa6bcd095688b48 370 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 37 129 8.0E-24 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 BWK49_RS27300 6718cb0da8bb43b6ffa6bcd095688b48 370 Pfam PF00107 Zinc-binding dehydrogenase 205 321 1.1E-17 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 BWK49_RS27300 6718cb0da8bb43b6ffa6bcd095688b48 370 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 69 83 - T 06-07-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 BWK49_RS27300 6718cb0da8bb43b6ffa6bcd095688b48 370 SUPERFAMILY SSF50129 319 368 4.43E-6 T 06-07-2017 IPR011032 GroES-like BWK49_RS27300 6718cb0da8bb43b6ffa6bcd095688b48 370 Gene3D G3DSA:3.40.50.720 198 311 3.6E-27 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS27300 6718cb0da8bb43b6ffa6bcd095688b48 370 SMART SM00829 19 366 2.7E-4 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 BWK49_RS27300 6718cb0da8bb43b6ffa6bcd095688b48 370 Gene3D G3DSA:3.90.180.10 19 197 3.4E-52 T 06-07-2017 IPR011032 GroES-like BWK49_RS27300 6718cb0da8bb43b6ffa6bcd095688b48 370 SUPERFAMILY SSF51735 167 333 3.71E-34 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS27300 6718cb0da8bb43b6ffa6bcd095688b48 370 SUPERFAMILY SSF50129 14 201 5.16E-55 T 06-07-2017 IPR011032 GroES-like BWK49_RS24235 a53ef1979248da621741e6c0af18ac17 179 Pfam PF00347 Ribosomal protein L6 11 83 1.0E-17 T 06-07-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 BWK49_RS24235 a53ef1979248da621741e6c0af18ac17 179 Pfam PF00347 Ribosomal protein L6 91 165 9.1E-22 T 06-07-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 BWK49_RS24235 a53ef1979248da621741e6c0af18ac17 179 PRINTS PR00059 Ribosomal protein L6 signature 100 116 7.5E-32 T 06-07-2017 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 BWK49_RS24235 a53ef1979248da621741e6c0af18ac17 179 PRINTS PR00059 Ribosomal protein L6 signature 142 163 7.5E-32 T 06-07-2017 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 BWK49_RS24235 a53ef1979248da621741e6c0af18ac17 179 PRINTS PR00059 Ribosomal protein L6 signature 72 97 7.5E-32 T 06-07-2017 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 BWK49_RS24235 a53ef1979248da621741e6c0af18ac17 179 SUPERFAMILY SSF56053 84 178 2.09E-35 T 06-07-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 BWK49_RS24235 a53ef1979248da621741e6c0af18ac17 179 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 155 163 - T 06-07-2017 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS24235 a53ef1979248da621741e6c0af18ac17 179 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 177 9.4E-73 T 06-07-2017 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 BWK49_RS24235 a53ef1979248da621741e6c0af18ac17 179 PIRSF PIRSF002162 1 178 3.8E-48 T 06-07-2017 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 BWK49_RS24235 a53ef1979248da621741e6c0af18ac17 179 SUPERFAMILY SSF56053 1 83 2.22E-25 T 06-07-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 BWK49_RS24235 a53ef1979248da621741e6c0af18ac17 179 Gene3D G3DSA:3.90.930.12 2 83 1.2E-29 T 06-07-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 BWK49_RS24235 a53ef1979248da621741e6c0af18ac17 179 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 177 38.202 T 06-07-2017 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 BWK49_RS24235 a53ef1979248da621741e6c0af18ac17 179 Gene3D G3DSA:3.90.930.12 84 178 3.5E-38 T 06-07-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 BWK49_RS02295 9d6d08db8ba64e63d03282523cd33c1e 305 Pfam PF13714 Phosphoenolpyruvate phosphomutase 19 260 2.7E-50 T 06-07-2017 BWK49_RS02295 9d6d08db8ba64e63d03282523cd33c1e 305 Hamap MF_01939 2-methylisocitrate lyase [prpB]. 12 298 47.073 T 06-07-2017 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 BWK49_RS02295 9d6d08db8ba64e63d03282523cd33c1e 305 Gene3D G3DSA:3.20.20.60 13 293 2.9E-93 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 BWK49_RS02295 9d6d08db8ba64e63d03282523cd33c1e 305 SUPERFAMILY SSF51621 12 296 1.08E-95 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 BWK49_RS02295 9d6d08db8ba64e63d03282523cd33c1e 305 TIGRFAM TIGR02317 prpB: methylisocitrate lyase 15 297 3.7E-120 T 06-07-2017 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 BWK49_RS02295 9d6d08db8ba64e63d03282523cd33c1e 305 ProSitePatterns PS00161 Isocitrate lyase signature. 127 132 - T 06-07-2017 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824|GO:0008152 BWK49_RS23945 d60d9a0d48ca0f32e6333c1deff9f727 98 Pfam PF06013 Proteins of 100 residues with WXG 16 90 6.7E-11 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like BWK49_RS23945 d60d9a0d48ca0f32e6333c1deff9f727 98 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 5 93 2.9E-20 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like BWK49_RS23945 d60d9a0d48ca0f32e6333c1deff9f727 98 Gene3D G3DSA:1.10.287.1060 5 97 4.1E-23 T 06-07-2017 BWK49_RS23945 d60d9a0d48ca0f32e6333c1deff9f727 98 SUPERFAMILY SSF140453 4 96 6.15E-21 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like BWK49_RS13195 2b85fe8640c3f0e2b7e95a8fcba0acd4 255 Pfam PF00459 Inositol monophosphatase family 38 251 5.4E-26 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 BWK49_RS13195 2b85fe8640c3f0e2b7e95a8fcba0acd4 255 Gene3D G3DSA:3.40.190.80 150 253 3.3E-24 T 06-07-2017 BWK49_RS13195 2b85fe8640c3f0e2b7e95a8fcba0acd4 255 SUPERFAMILY SSF56655 3 253 5.1E-46 T 06-07-2017 BWK49_RS13195 2b85fe8640c3f0e2b7e95a8fcba0acd4 255 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 76 89 - T 06-07-2017 IPR020583 Inositol monophosphatase, metal-binding site BWK49_RS13195 2b85fe8640c3f0e2b7e95a8fcba0acd4 255 Gene3D G3DSA:3.30.540.10 5 149 1.1E-20 T 06-07-2017 BWK49_RS28200 0340da23064845679180ceeb4276d469 206 SUPERFAMILY SSF48498 88 198 4.04E-6 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS28200 0340da23064845679180ceeb4276d469 206 SUPERFAMILY SSF46689 14 92 3.94E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS28200 0340da23064845679180ceeb4276d469 206 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 67 1.2E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS28200 0340da23064845679180ceeb4276d469 206 Gene3D G3DSA:1.10.357.10 15 196 4.5E-30 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS28200 0340da23064845679180ceeb4276d469 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 2.6E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS28200 0340da23064845679180ceeb4276d469 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 2.6E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS03000 81146a666f9f8cee77abf20c6a0135d3 320 Pfam PF09179 TilS substrate binding domain 242 296 6.6E-10 T 06-07-2017 IPR015262 tRNA(Ile)-lysidine synthase , substrate-binding domain GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 BWK49_RS03000 81146a666f9f8cee77abf20c6a0135d3 320 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 10 301 18.411 T 06-07-2017 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 BWK49_RS03000 81146a666f9f8cee77abf20c6a0135d3 320 SUPERFAMILY SSF52402 23 226 1.12E-42 T 06-07-2017 BWK49_RS03000 81146a666f9f8cee77abf20c6a0135d3 320 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 29 197 1.5E-34 T 06-07-2017 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 BWK49_RS03000 81146a666f9f8cee77abf20c6a0135d3 320 Pfam PF01171 PP-loop family 28 193 2.0E-30 T 06-07-2017 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 BWK49_RS03000 81146a666f9f8cee77abf20c6a0135d3 320 Gene3D G3DSA:3.40.50.620 4 78 3.3E-7 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold BWK49_RS03000 81146a666f9f8cee77abf20c6a0135d3 320 SUPERFAMILY SSF82829 206 297 1.26E-11 T 06-07-2017 BWK49_RS13660 8acb929552020d8fb19d6dcf8f9dae6c 509 SUPERFAMILY SSF53300 325 504 1.3E-14 T 06-07-2017 IPR002035 von Willebrand factor, type A BWK49_RS13660 8acb929552020d8fb19d6dcf8f9dae6c 509 Gene3D G3DSA:3.40.50.410 327 471 3.0E-7 T 06-07-2017 IPR002035 von Willebrand factor, type A BWK49_RS15635 3dcc2f31cf7e790fc80a235a4b5e9d3c 365 Gene3D G3DSA:3.10.20.30 266 363 6.7E-20 T 06-07-2017 IPR012675 Beta-grasp domain BWK49_RS15635 3dcc2f31cf7e790fc80a235a4b5e9d3c 365 SUPERFAMILY SSF63380 46 145 6.19E-19 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 BWK49_RS15635 3dcc2f31cf7e790fc80a235a4b5e9d3c 365 Pfam PF00970 Oxidoreductase FAD-binding domain 75 136 1.4E-7 T 06-07-2017 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 BWK49_RS15635 3dcc2f31cf7e790fc80a235a4b5e9d3c 365 Pfam PF00175 Oxidoreductase NAD-binding domain 155 216 2.7E-7 T 06-07-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 BWK49_RS15635 3dcc2f31cf7e790fc80a235a4b5e9d3c 365 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 290 343 2.7E-7 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 BWK49_RS15635 3dcc2f31cf7e790fc80a235a4b5e9d3c 365 SUPERFAMILY SSF52343 143 271 1.7E-24 T 06-07-2017 BWK49_RS15635 3dcc2f31cf7e790fc80a235a4b5e9d3c 365 SUPERFAMILY SSF54292 260 363 3.67E-17 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 BWK49_RS15635 3dcc2f31cf7e790fc80a235a4b5e9d3c 365 Gene3D G3DSA:2.40.30.10 34 136 8.9E-19 T 06-07-2017 BWK49_RS15635 3dcc2f31cf7e790fc80a235a4b5e9d3c 365 Gene3D G3DSA:3.40.50.80 152 265 5.3E-24 T 06-07-2017 BWK49_RS07275 b914591c28735ee520afbf5b671ace81 621 SMART SM00267 168 338 8.0E-48 T 06-07-2017 IPR000160 GGDEF domain BWK49_RS07275 b914591c28735ee520afbf5b671ace81 621 SUPERFAMILY SSF55073 184 338 3.53E-38 T 06-07-2017 IPR029787 Nucleotide cyclase BWK49_RS07275 b914591c28735ee520afbf5b671ace81 621 Gene3D G3DSA:3.30.450.40 25 179 2.9E-9 T 06-07-2017 IPR029016 GAF domain-like BWK49_RS07275 b914591c28735ee520afbf5b671ace81 621 Pfam PF00563 EAL domain 356 590 2.0E-66 T 06-07-2017 IPR001633 EAL domain BWK49_RS07275 b914591c28735ee520afbf5b671ace81 621 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 177 338 3.0E-30 T 06-07-2017 IPR000160 GGDEF domain BWK49_RS07275 b914591c28735ee520afbf5b671ace81 621 SUPERFAMILY SSF141868 356 604 6.02E-81 T 06-07-2017 IPR001633 EAL domain BWK49_RS07275 b914591c28735ee520afbf5b671ace81 621 SUPERFAMILY SSF55781 29 179 1.91E-11 T 06-07-2017 IPR029016 GAF domain-like BWK49_RS07275 b914591c28735ee520afbf5b671ace81 621 Gene3D G3DSA:3.20.20.450 353 602 2.7E-86 T 06-07-2017 IPR001633 EAL domain BWK49_RS07275 b914591c28735ee520afbf5b671ace81 621 Gene3D G3DSA:3.30.70.270 180 343 2.7E-42 T 06-07-2017 BWK49_RS07275 b914591c28735ee520afbf5b671ace81 621 Pfam PF00990 Diguanylate cyclase, GGDEF domain 179 334 8.0E-33 T 06-07-2017 IPR000160 GGDEF domain BWK49_RS07275 b914591c28735ee520afbf5b671ace81 621 SMART SM00052 348 595 7.9E-102 T 06-07-2017 IPR001633 EAL domain BWK49_RS07275 b914591c28735ee520afbf5b671ace81 621 SMART SM00065 23 176 1.7E-4 T 06-07-2017 IPR003018 GAF domain GO:0005515 BWK49_RS07275 b914591c28735ee520afbf5b671ace81 621 Pfam PF13185 GAF domain 24 164 3.8E-7 T 06-07-2017 IPR003018 GAF domain GO:0005515 BWK49_RS01335 702d7c7b6410bf60bca706742cc87fbe 355 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 214 223 - T 06-07-2017 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 BWK49_RS01335 702d7c7b6410bf60bca706742cc87fbe 355 SUPERFAMILY SSF53383 17 344 1.24E-75 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase BWK49_RS01335 702d7c7b6410bf60bca706742cc87fbe 355 Pfam PF00155 Aminotransferase class I and II 25 340 8.9E-53 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 BWK49_RS01335 702d7c7b6410bf60bca706742cc87fbe 355 Hamap MF_01513 Putative phenylalanine aminotransferase [pat]. 5 351 45.419 T 06-07-2017 IPR024892 Putative phenylalanine aminotransferase BWK49_RS01335 702d7c7b6410bf60bca706742cc87fbe 355 Gene3D G3DSA:3.90.1150.10 239 349 1.1E-31 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 BWK49_RS01335 702d7c7b6410bf60bca706742cc87fbe 355 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 4 350 47.858 T 06-07-2017 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 BWK49_RS01335 702d7c7b6410bf60bca706742cc87fbe 355 Gene3D G3DSA:3.40.640.10 39 238 7.5E-47 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 BWK49_RS01335 702d7c7b6410bf60bca706742cc87fbe 355 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 7 346 2.2E-83 T 06-07-2017 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 BWK49_RS28675 140d76e4460c6f2406656252256aff5f 318 Pfam PF00487 Fatty acid desaturase 61 294 5.9E-30 T 06-07-2017 IPR005804 Fatty acid desaturase domain GO:0006629 BWK49_RS19735 4f8f336d55f252ebfcc4acc242273bf7 153 SUPERFAMILY SSF52218 4 150 3.06E-24 T 06-07-2017 IPR029039 Flavoprotein-like domain BWK49_RS19735 4f8f336d55f252ebfcc4acc242273bf7 153 Gene3D G3DSA:3.40.50.360 3 150 8.0E-28 T 06-07-2017 IPR029039 Flavoprotein-like domain BWK49_RS17975 a3fa95b6f081b778977fa0fbf7fa25aa 153 SUPERFAMILY SSF51182 7 148 9.57E-21 T 06-07-2017 IPR011051 RmlC-like cupin domain BWK49_RS17975 a3fa95b6f081b778977fa0fbf7fa25aa 153 Gene3D G3DSA:2.60.120.10 7 151 8.9E-30 T 06-07-2017 IPR014710 RmlC-like jelly roll fold BWK49_RS17975 a3fa95b6f081b778977fa0fbf7fa25aa 153 Pfam PF07883 Cupin domain 29 94 1.9E-14 T 06-07-2017 IPR013096 Cupin 2, conserved barrel BWK49_RS21090 d88b9dbc656eace0d4766783eea82b45 274 SUPERFAMILY SSF53335 39 208 7.3E-35 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS21090 d88b9dbc656eace0d4766783eea82b45 274 Pfam PF08241 Methyltransferase domain 62 152 1.1E-21 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 BWK49_RS21090 d88b9dbc656eace0d4766783eea82b45 274 Gene3D G3DSA:3.40.50.150 57 208 1.5E-36 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS06890 4cc263fbef84f062cd9a9c6338dc7f59 307 Pfam PF00294 pfkB family carbohydrate kinase 6 293 7.1E-39 T 06-07-2017 IPR011611 Carbohydrate kinase PfkB BWK49_RS06890 4cc263fbef84f062cd9a9c6338dc7f59 307 Gene3D G3DSA:3.40.1190.20 5 303 3.2E-58 T 06-07-2017 IPR029056 Ribokinase-like BWK49_RS06890 4cc263fbef84f062cd9a9c6338dc7f59 307 SUPERFAMILY SSF53613 3 297 7.95E-54 T 06-07-2017 IPR029056 Ribokinase-like BWK49_RS06890 4cc263fbef84f062cd9a9c6338dc7f59 307 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 233 246 - T 06-07-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 BWK49_RS12065 e7145377f7f757062810ce5dc9d120e6 301 Hamap MF_01230 Haloalkane dehalogenase [dhmA]. 1 298 57.888 T 06-07-2017 IPR023489 Haloalkane dehalogenase, subfamily 1 GO:0018786 KEGG: 00361+3.8.1.5|KEGG: 00625+3.8.1.5 BWK49_RS12065 e7145377f7f757062810ce5dc9d120e6 301 Pfam PF00561 alpha/beta hydrolase fold 47 284 4.7E-20 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS12065 e7145377f7f757062810ce5dc9d120e6 301 PRINTS PR00111 Alpha/beta hydrolase fold signature 73 88 1.9E-7 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS12065 e7145377f7f757062810ce5dc9d120e6 301 PRINTS PR00111 Alpha/beta hydrolase fold signature 133 146 1.9E-7 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS12065 e7145377f7f757062810ce5dc9d120e6 301 Gene3D G3DSA:3.40.50.1820 3 297 4.5E-57 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS12065 e7145377f7f757062810ce5dc9d120e6 301 SUPERFAMILY SSF53474 31 296 1.75E-53 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS12065 e7145377f7f757062810ce5dc9d120e6 301 PRINTS PR00412 Epoxide hydrolase signature 133 146 5.9E-12 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS12065 e7145377f7f757062810ce5dc9d120e6 301 PRINTS PR00412 Epoxide hydrolase signature 73 88 5.9E-12 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS12065 e7145377f7f757062810ce5dc9d120e6 301 PRINTS PR00412 Epoxide hydrolase signature 53 71 5.9E-12 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS12065 e7145377f7f757062810ce5dc9d120e6 301 PRINTS PR00412 Epoxide hydrolase signature 274 296 5.9E-12 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS12065 e7145377f7f757062810ce5dc9d120e6 301 PRINTS PR00412 Epoxide hydrolase signature 119 132 5.9E-12 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS24855 7b952254255098d43aa28706c6526038 230 Pfam PF01209 ubiE/COQ5 methyltransferase family 11 226 1.9E-57 T 06-07-2017 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 BWK49_RS24855 7b952254255098d43aa28706c6526038 230 Gene3D G3DSA:3.40.50.150 13 222 5.7E-43 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS24855 7b952254255098d43aa28706c6526038 230 SUPERFAMILY SSF53335 5 225 3.72E-40 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS24855 7b952254255098d43aa28706c6526038 230 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 135 149 - T 06-07-2017 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 BWK49_RS24855 7b952254255098d43aa28706c6526038 230 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 24 39 - T 06-07-2017 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 BWK49_RS24855 7b952254255098d43aa28706c6526038 230 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 4 227 32.978 T 06-07-2017 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 BWK49_RS24855 7b952254255098d43aa28706c6526038 230 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 13 226 5.3E-73 T 06-07-2017 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 BWK49_RS05620 51bc4afc122a6363f008314a58699055 135 SUPERFAMILY SSF88723 2 129 5.33E-8 T 06-07-2017 IPR029060 PIN domain-like BWK49_RS05620 51bc4afc122a6363f008314a58699055 135 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 128 12.555 T 06-07-2017 IPR022907 VapC family GO:0004540 BWK49_RS05620 51bc4afc122a6363f008314a58699055 135 Pfam PF01850 PIN domain 2 121 1.4E-13 T 06-07-2017 IPR002716 PIN domain BWK49_RS27255 bc6e68fe310371aae43a5506a66b4ed0 520 Pfam PF02470 MlaD protein 40 111 1.0E-11 T 06-07-2017 IPR003399 Mce/MlaD BWK49_RS27255 bc6e68fe310371aae43a5506a66b4ed0 520 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 11 290 9.2E-79 T 06-07-2017 IPR005693 Virulence factor Mce protein BWK49_RS27255 bc6e68fe310371aae43a5506a66b4ed0 520 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 128 152 4.0E-93 T 06-07-2017 IPR005693 Virulence factor Mce protein BWK49_RS27255 bc6e68fe310371aae43a5506a66b4ed0 520 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 246 265 4.0E-93 T 06-07-2017 IPR005693 Virulence factor Mce protein BWK49_RS27255 bc6e68fe310371aae43a5506a66b4ed0 520 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 28 48 4.0E-93 T 06-07-2017 IPR005693 Virulence factor Mce protein BWK49_RS27255 bc6e68fe310371aae43a5506a66b4ed0 520 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 346 364 4.0E-93 T 06-07-2017 IPR005693 Virulence factor Mce protein BWK49_RS27255 bc6e68fe310371aae43a5506a66b4ed0 520 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 177 195 4.0E-93 T 06-07-2017 IPR005693 Virulence factor Mce protein BWK49_RS27255 bc6e68fe310371aae43a5506a66b4ed0 520 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 325 342 4.0E-93 T 06-07-2017 IPR005693 Virulence factor Mce protein BWK49_RS27255 bc6e68fe310371aae43a5506a66b4ed0 520 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 90 106 4.0E-93 T 06-07-2017 IPR005693 Virulence factor Mce protein BWK49_RS27255 bc6e68fe310371aae43a5506a66b4ed0 520 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 296 315 4.0E-93 T 06-07-2017 IPR005693 Virulence factor Mce protein BWK49_RS27255 bc6e68fe310371aae43a5506a66b4ed0 520 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 157 301 4.1E-7 T 06-07-2017 IPR024516 Mammalian cell entry, C-terminal BWK49_RS17225 8c027e685e394e313e84c4cd93350ba4 537 Pfam PF00005 ABC transporter 340 483 2.5E-25 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 BWK49_RS17225 8c027e685e394e313e84c4cd93350ba4 537 SUPERFAMILY SSF52540 318 532 9.35E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS17225 8c027e685e394e313e84c4cd93350ba4 537 SMART SM00382 346 533 3.1E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS17225 8c027e685e394e313e84c4cd93350ba4 537 SUPERFAMILY SSF90123 2 303 2.49E-38 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 BWK49_RS17225 8c027e685e394e313e84c4cd93350ba4 537 ProSitePatterns PS00211 ABC transporters family signature. 455 469 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 BWK49_RS17225 8c027e685e394e313e84c4cd93350ba4 537 Pfam PF00664 ABC transporter transmembrane region 10 263 2.4E-15 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 BWK49_RS17225 8c027e685e394e313e84c4cd93350ba4 537 TIGRFAM TIGR02857 CydD: thiol reductant ABC exporter, CydD subunit 2 525 5.5E-147 T 06-07-2017 IPR014216 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD GO:0005524|GO:0016020|GO:0042883 BWK49_RS17225 8c027e685e394e313e84c4cd93350ba4 537 Gene3D G3DSA:1.20.1560.10 2 302 7.8E-35 T 06-07-2017 BWK49_RS17225 8c027e685e394e313e84c4cd93350ba4 537 Gene3D G3DSA:3.40.50.300 323 526 1.9E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS10875 c780b446e9cc77771db321770be097ff 270 Gene3D G3DSA:3.20.20.150 1 249 1.2E-31 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain BWK49_RS10875 c780b446e9cc77771db321770be097ff 270 Pfam PF01261 Xylose isomerase-like TIM barrel 37 198 1.2E-12 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain BWK49_RS10875 c780b446e9cc77771db321770be097ff 270 SUPERFAMILY SSF51658 3 268 5.39E-44 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain BWK49_RS24250 e21d9f0af8c0e4e55cf19d4080074be0 187 Pfam PF00281 Ribosomal protein L5 31 87 2.6E-25 T 06-07-2017 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 BWK49_RS24250 e21d9f0af8c0e4e55cf19d4080074be0 187 Gene3D G3DSA:3.30.1440.10 8 185 1.6E-73 T 06-07-2017 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 BWK49_RS24250 e21d9f0af8c0e4e55cf19d4080074be0 187 Pfam PF00673 ribosomal L5P family C-terminus 91 184 2.3E-38 T 06-07-2017 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 BWK49_RS24250 e21d9f0af8c0e4e55cf19d4080074be0 187 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 8 186 43.189 T 06-07-2017 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS24250 e21d9f0af8c0e4e55cf19d4080074be0 187 SUPERFAMILY SSF55282 10 185 7.06E-73 T 06-07-2017 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 BWK49_RS24250 e21d9f0af8c0e4e55cf19d4080074be0 187 PIRSF PIRSF002161 4 187 1.1E-62 T 06-07-2017 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 BWK49_RS28640 0c3eac17bf0e3691380616f6f6e50215 94 SUPERFAMILY SSF143120 5 81 2.35E-17 T 06-07-2017 BWK49_RS28640 0c3eac17bf0e3691380616f6f6e50215 94 Gene3D G3DSA:3.40.1620.10 4 51 5.0E-15 T 06-07-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM BWK49_RS28640 0c3eac17bf0e3691380616f6f6e50215 94 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 6 54 4.6E-16 T 06-07-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM BWK49_RS28640 0c3eac17bf0e3691380616f6f6e50215 94 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 4 74 6.0E-20 T 06-07-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM BWK49_RS13570 0c0cb8ed5c51f0a44aa00b55591fd1bf 126 TIGRFAM TIGR03666 Rv2061_F420: PPOX class probable F420-dependent enzyme, Rv2061 family 2 125 1.0E-55 T 06-07-2017 IPR019965 PPOX class F420-dependent enzyme, family Rv2061, putative BWK49_RS13570 0c0cb8ed5c51f0a44aa00b55591fd1bf 126 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 6 83 6.8E-12 T 06-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 BWK49_RS13570 0c0cb8ed5c51f0a44aa00b55591fd1bf 126 SUPERFAMILY SSF50475 8 116 7.86E-21 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 BWK49_RS13570 0c0cb8ed5c51f0a44aa00b55591fd1bf 126 Gene3D G3DSA:2.30.110.10 8 99 2.6E-17 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 BWK49_RS14975 705151740f70498ac5cffe76ef505028 126 Pfam PF13827 Domain of unknown function (DUF4189) 27 106 1.3E-13 T 06-07-2017 IPR025240 Domain of unknown function DUF4189 BWK49_RS14975 705151740f70498ac5cffe76ef505028 126 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 7 112 1.0E-33 T 06-07-2017 BWK49_RS17630 976f406341aa822da71aaaa4e47638bd 971 SUPERFAMILY SSF82866 151 346 2.62E-28 T 06-07-2017 BWK49_RS17630 976f406341aa822da71aaaa4e47638bd 971 TIGRFAM TIGR00833 actII: transport protein 17 926 0.0 T 06-07-2017 IPR004707 Membrane transport protein MmpL family GO:0016021 BWK49_RS17630 976f406341aa822da71aaaa4e47638bd 971 SUPERFAMILY SSF82866 698 926 1.7E-30 T 06-07-2017 BWK49_RS17630 976f406341aa822da71aaaa4e47638bd 971 Pfam PF03176 MMPL family 599 934 6.2E-111 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 BWK49_RS17630 976f406341aa822da71aaaa4e47638bd 971 Pfam PF03176 MMPL family 51 379 3.5E-118 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 BWK49_RS17630 976f406341aa822da71aaaa4e47638bd 971 Gene3D G3DSA:1.20.1640.10 151 347 8.5E-28 T 06-07-2017 BWK49_RS17630 976f406341aa822da71aaaa4e47638bd 971 Gene3D G3DSA:1.20.1640.10 722 926 1.1E-23 T 06-07-2017 BWK49_RS14680 4480b91d16eccd4f25b70c5a7bbc07ec 341 Gene3D G3DSA:3.90.180.10 1 167 3.0E-46 T 06-07-2017 IPR011032 GroES-like BWK49_RS14680 4480b91d16eccd4f25b70c5a7bbc07ec 341 SUPERFAMILY SSF50129 1 163 6.43E-48 T 06-07-2017 IPR011032 GroES-like BWK49_RS14680 4480b91d16eccd4f25b70c5a7bbc07ec 341 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 128 1.0E-25 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 BWK49_RS14680 4480b91d16eccd4f25b70c5a7bbc07ec 341 SUPERFAMILY SSF51735 138 306 2.71E-35 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS14680 4480b91d16eccd4f25b70c5a7bbc07ec 341 SMART SM00829 8 339 2.7E-5 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 BWK49_RS14680 4480b91d16eccd4f25b70c5a7bbc07ec 341 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 58 72 - T 06-07-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 BWK49_RS14680 4480b91d16eccd4f25b70c5a7bbc07ec 341 Pfam PF00107 Zinc-binding dehydrogenase 176 300 4.2E-20 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 BWK49_RS14680 4480b91d16eccd4f25b70c5a7bbc07ec 341 Gene3D G3DSA:3.40.50.720 168 284 4.2E-29 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS15360 361b33b98c0f4c89e4a6d97306707576 95 Pfam PF03861 ANTAR domain 18 61 1.6E-4 T 06-07-2017 IPR005561 ANTAR domain GO:0003723 BWK49_RS15360 361b33b98c0f4c89e4a6d97306707576 95 SMART SM01012 6 61 1.8E-4 T 06-07-2017 IPR005561 ANTAR domain GO:0003723 BWK49_RS17670 07a90d3ca931d4308ed1ac5dd1acab80 407 Pfam PF08484 C-methyltransferase C-terminal domain 244 402 3.2E-58 T 06-07-2017 IPR013691 C-methyltransferase BWK49_RS17670 07a90d3ca931d4308ed1ac5dd1acab80 407 SUPERFAMILY SSF53335 56 251 2.88E-21 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS17670 07a90d3ca931d4308ed1ac5dd1acab80 407 Pfam PF13489 Methyltransferase domain 101 238 1.9E-11 T 06-07-2017 BWK49_RS17670 07a90d3ca931d4308ed1ac5dd1acab80 407 Gene3D G3DSA:3.40.50.150 87 258 8.7E-23 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS17670 07a90d3ca931d4308ed1ac5dd1acab80 407 Pfam PF08421 Putative zinc binding domain 3 64 2.2E-22 T 06-07-2017 IPR013630 Methyltransferase putative zinc binding domain BWK49_RS00325 e082d909da2b51575c7d524037a2df72 267 Gene3D G3DSA:3.20.20.150 7 255 1.7E-28 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain BWK49_RS00325 e082d909da2b51575c7d524037a2df72 267 Pfam PF01261 Xylose isomerase-like TIM barrel 70 215 1.3E-17 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain BWK49_RS00325 e082d909da2b51575c7d524037a2df72 267 SUPERFAMILY SSF51658 7 265 2.36E-33 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain BWK49_RS21350 95160b0d64bef84a786c48df37c739df 184 SUPERFAMILY SSF52218 4 175 2.1E-36 T 06-07-2017 IPR029039 Flavoprotein-like domain BWK49_RS21350 95160b0d64bef84a786c48df37c739df 184 Gene3D G3DSA:3.40.50.360 3 181 8.3E-41 T 06-07-2017 IPR029039 Flavoprotein-like domain BWK49_RS21350 95160b0d64bef84a786c48df37c739df 184 Pfam PF03358 NADPH-dependent FMN reductase 4 153 7.1E-33 T 06-07-2017 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 BWK49_RS18825 2943232db7d1a2e2b063093fc3bb3a10 128 Pfam PF06993 Protein of unknown function (DUF1304) 10 123 7.4E-33 T 06-07-2017 IPR009732 Protein of unknown function DUF1304 BWK49_RS04790 af164fb03746a55e6079833c1cf1084f 352 Gene3D G3DSA:3.20.20.30 11 336 1.6E-58 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS04790 af164fb03746a55e6079833c1cf1084f 352 SUPERFAMILY SSF51679 13 334 7.98E-58 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS04790 af164fb03746a55e6079833c1cf1084f 352 Pfam PF00296 Luciferase-like monooxygenase 11 304 4.3E-59 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS06765 a97f07e3b9b60d88aeb312fc71eae20b 153 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 1 141 3.1E-21 T 06-07-2017 IPR019587 Polyketide cyclase/dehydrase BWK49_RS06765 a97f07e3b9b60d88aeb312fc71eae20b 153 Gene3D G3DSA:3.30.530.20 2 140 6.9E-16 T 06-07-2017 IPR023393 START-like domain BWK49_RS06765 a97f07e3b9b60d88aeb312fc71eae20b 153 SUPERFAMILY SSF55961 1 139 8.84E-22 T 06-07-2017 BWK49_RS20735 e5f78c0366e9372ecb3ef782622e2168 184 PIRSF PIRSF004553 1 184 7.0E-65 T 06-07-2017 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 BWK49_RS20735 e5f78c0366e9372ecb3ef782622e2168 184 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 116 122 - T 06-07-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 BWK49_RS20735 e5f78c0366e9372ecb3ef782622e2168 184 Gene3D G3DSA:3.40.50.150 2 183 6.8E-54 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS20735 e5f78c0366e9372ecb3ef782622e2168 184 SUPERFAMILY SSF53335 2 180 1.19E-39 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS20735 e5f78c0366e9372ecb3ef782622e2168 184 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 3 183 7.8E-55 T 06-07-2017 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 BWK49_RS20735 e5f78c0366e9372ecb3ef782622e2168 184 Pfam PF03602 Conserved hypothetical protein 95 2 180 1.1E-48 T 06-07-2017 BWK49_RS20455 364fcf07547b724e3147376a01f17e01 208 SUPERFAMILY SSF55729 59 179 1.74E-15 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase BWK49_RS20455 364fcf07547b724e3147376a01f17e01 208 Gene3D G3DSA:3.40.630.30 54 178 7.4E-16 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase BWK49_RS20455 364fcf07547b724e3147376a01f17e01 208 Pfam PF13508 Acetyltransferase (GNAT) domain 116 174 2.1E-8 T 06-07-2017 IPR000182 GNAT domain GO:0008080 BWK49_RS05280 278badbc42e243271a674deb93572e92 290 Gene3D G3DSA:3.10.129.10 142 268 4.1E-41 T 06-07-2017 IPR029069 HotDog domain BWK49_RS05280 278badbc42e243271a674deb93572e92 290 SUPERFAMILY SSF54637 7 155 4.09E-37 T 06-07-2017 IPR029069 HotDog domain BWK49_RS05280 278badbc42e243271a674deb93572e92 290 Gene3D G3DSA:3.10.129.10 1 141 1.1E-41 T 06-07-2017 IPR029069 HotDog domain BWK49_RS05280 278badbc42e243271a674deb93572e92 290 Pfam PF13452 N-terminal half of MaoC dehydratase 7 134 1.1E-7 T 06-07-2017 BWK49_RS05280 278badbc42e243271a674deb93572e92 290 SUPERFAMILY SSF54637 160 268 9.47E-30 T 06-07-2017 IPR029069 HotDog domain BWK49_RS05280 278badbc42e243271a674deb93572e92 290 Pfam PF01575 MaoC like domain 161 266 3.4E-31 T 06-07-2017 IPR002539 MaoC-like domain BWK49_RS22525 a0d96de807d6154002d4ceb9596b421b 307 Gene3D G3DSA:1.10.10.60 257 304 9.1E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS22525 a0d96de807d6154002d4ceb9596b421b 307 Pfam PF12833 Helix-turn-helix domain 225 304 4.8E-20 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 BWK49_RS22525 a0d96de807d6154002d4ceb9596b421b 307 SUPERFAMILY SSF46689 202 253 2.91E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS22525 a0d96de807d6154002d4ceb9596b421b 307 Gene3D G3DSA:1.10.10.60 198 256 3.6E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS22525 a0d96de807d6154002d4ceb9596b421b 307 SUPERFAMILY SSF46689 255 305 1.39E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS22525 a0d96de807d6154002d4ceb9596b421b 307 SMART SM00342 219 302 4.0E-23 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 BWK49_RS01445 522e8e050475b290f5aecbd1710b7379 419 Pfam PF02470 MlaD protein 39 113 2.5E-17 T 06-07-2017 IPR003399 Mce/MlaD BWK49_RS01445 522e8e050475b290f5aecbd1710b7379 419 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 13 292 2.8E-71 T 06-07-2017 IPR005693 Virulence factor Mce protein BWK49_RS01445 522e8e050475b290f5aecbd1710b7379 419 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 141 301 2.7E-7 T 06-07-2017 IPR024516 Mammalian cell entry, C-terminal BWK49_RS01445 522e8e050475b290f5aecbd1710b7379 419 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 296 315 4.2E-23 T 06-07-2017 IPR005693 Virulence factor Mce protein BWK49_RS01445 522e8e050475b290f5aecbd1710b7379 419 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 28 48 4.2E-23 T 06-07-2017 IPR005693 Virulence factor Mce protein BWK49_RS01445 522e8e050475b290f5aecbd1710b7379 419 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 176 194 4.2E-23 T 06-07-2017 IPR005693 Virulence factor Mce protein BWK49_RS01445 522e8e050475b290f5aecbd1710b7379 419 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 91 107 4.2E-23 T 06-07-2017 IPR005693 Virulence factor Mce protein BWK49_RS01445 522e8e050475b290f5aecbd1710b7379 419 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 127 151 4.2E-23 T 06-07-2017 IPR005693 Virulence factor Mce protein BWK49_RS25415 b47dc4c5f741dc96b08574f9d6abe1a8 275 Pfam PF00795 Carbon-nitrogen hydrolase 2 254 5.8E-39 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 BWK49_RS25415 b47dc4c5f741dc96b08574f9d6abe1a8 275 SUPERFAMILY SSF56317 1 262 2.22E-64 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 BWK49_RS25415 b47dc4c5f741dc96b08574f9d6abe1a8 275 Gene3D G3DSA:3.60.110.10 1 263 8.0E-68 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 BWK49_RS25415 b47dc4c5f741dc96b08574f9d6abe1a8 275 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 139 159 - T 06-07-2017 IPR001110 Uncharacterised protein family UPF0012, conserved site BWK49_RS03525 f25a3f5e909df9d2d9a91f4b2f1aad34 226 Pfam PF06314 Acetoacetate decarboxylase (ADC) 2 219 1.9E-42 T 06-07-2017 IPR010451 Acetoacetate decarboxylase GO:0016829 KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 BWK49_RS03525 f25a3f5e909df9d2d9a91f4b2f1aad34 226 Gene3D G3DSA:2.40.400.10 2 223 1.9E-22 T 06-07-2017 IPR023375 Acetoacetate decarboxylase beta barrel domain KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 BWK49_RS03525 f25a3f5e909df9d2d9a91f4b2f1aad34 226 SUPERFAMILY SSF160104 2 225 1.96E-44 T 06-07-2017 BWK49_RS24365 48bd134dce2bf05a76f7362eaa33c734 403 Pfam PF13186 Iron-sulfur cluster-binding domain 255 317 6.5E-5 T 06-07-2017 IPR023885 4Fe4S-binding SPASM domain BWK49_RS24365 48bd134dce2bf05a76f7362eaa33c734 403 SUPERFAMILY SSF102114 23 327 1.31E-61 T 06-07-2017 BWK49_RS24365 48bd134dce2bf05a76f7362eaa33c734 403 Pfam PF04055 Radical SAM superfamily 30 184 9.0E-27 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 BWK49_RS24365 48bd134dce2bf05a76f7362eaa33c734 403 TIGRFAM TIGR03962 mycofact_rSAM: mycofactocin radical SAM maturase 13 352 2.8E-203 T 06-07-2017 IPR023913 Mycofactocin, radical SAM peptide maturase BWK49_RS24365 48bd134dce2bf05a76f7362eaa33c734 403 SMART SM00729 24 223 4.5E-4 T 06-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 BWK49_RS24365 48bd134dce2bf05a76f7362eaa33c734 403 Gene3D G3DSA:3.20.20.70 23 332 7.4E-65 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 BWK49_RS24365 48bd134dce2bf05a76f7362eaa33c734 403 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 255 335 2.3E-13 T 06-07-2017 IPR023885 4Fe4S-binding SPASM domain BWK49_RS08065 a134e1936e9406061d01a14d5c43f16f 370 SUPERFAMILY SSF47203 227 365 8.54E-32 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS08065 a134e1936e9406061d01a14d5c43f16f 370 Gene3D G3DSA:1.20.140.10 228 363 8.0E-30 T 06-07-2017 BWK49_RS08065 a134e1936e9406061d01a14d5c43f16f 370 Gene3D G3DSA:2.40.110.10 136 227 1.8E-4 T 06-07-2017 BWK49_RS08065 a134e1936e9406061d01a14d5c43f16f 370 SUPERFAMILY SSF56645 1 195 6.68E-30 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS08065 a134e1936e9406061d01a14d5c43f16f 370 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 118 1.0E-15 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS08065 a134e1936e9406061d01a14d5c43f16f 370 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 228 363 9.9E-21 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS08065 a134e1936e9406061d01a14d5c43f16f 370 Gene3D G3DSA:1.10.540.10 4 120 2.0E-16 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS13215 f1a7a1563a58f7c2b245f218d5b713b9 77 SMART SM00923 4 54 4.4E-32 T 06-07-2017 IPR005153 MbtH-like protein BWK49_RS13215 f1a7a1563a58f7c2b245f218d5b713b9 77 Pfam PF03621 MbtH-like protein 2 54 8.7E-29 T 06-07-2017 IPR005153 MbtH-like protein BWK49_RS13215 f1a7a1563a58f7c2b245f218d5b713b9 77 SUPERFAMILY SSF160582 3 69 8.11E-30 T 06-07-2017 BWK49_RS13215 f1a7a1563a58f7c2b245f218d5b713b9 77 Gene3D G3DSA:3.90.820.10 12 70 1.4E-30 T 06-07-2017 BWK49_RS22055 16dc893f3c6459bdea9d2364c8748066 529 Pfam PF00361 Proton-conducting membrane transporter 170 463 7.9E-71 T 06-07-2017 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS22055 16dc893f3c6459bdea9d2364c8748066 529 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 8 518 17.523 T 06-07-2017 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 BWK49_RS22055 16dc893f3c6459bdea9d2364c8748066 529 TIGRFAM TIGR01770 NDH_I_N: proton-translocating NADH-quinone oxidoreductase, chain N 143 517 1.1E-114 T 06-07-2017 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 BWK49_RS21360 357b92316443a2d2c2ac061d2b736079 347 Pfam PF11799 impB/mucB/samB family C-terminal domain 245 345 3.1E-8 T 06-07-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 BWK49_RS21360 357b92316443a2d2c2ac061d2b736079 347 Hamap MF_01113 DNA polymerase IV [dinB]. 6 345 28.639 T 06-07-2017 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 BWK49_RS21360 357b92316443a2d2c2ac061d2b736079 347 Gene3D G3DSA:3.30.1490.100 247 344 4.7E-16 T 06-07-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 BWK49_RS21360 357b92316443a2d2c2ac061d2b736079 347 Gene3D G3DSA:3.30.70.270 74 166 4.5E-20 T 06-07-2017 BWK49_RS21360 357b92316443a2d2c2ac061d2b736079 347 SUPERFAMILY SSF56672 8 239 2.58E-68 T 06-07-2017 BWK49_RS21360 357b92316443a2d2c2ac061d2b736079 347 Gene3D G3DSA:1.10.150.20 169 241 2.3E-17 T 06-07-2017 BWK49_RS21360 357b92316443a2d2c2ac061d2b736079 347 Pfam PF11798 IMS family HHH motif 170 200 3.8E-6 T 06-07-2017 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 BWK49_RS21360 357b92316443a2d2c2ac061d2b736079 347 SUPERFAMILY SSF100879 244 341 2.16E-17 T 06-07-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 BWK49_RS21360 357b92316443a2d2c2ac061d2b736079 347 Pfam PF00817 impB/mucB/samB family 12 156 1.7E-37 T 06-07-2017 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 BWK49_RS25270 176845732b092795c00313a0966a4ebd 89 Pfam PF05768 Glutaredoxin-like domain (DUF836) 10 87 1.2E-15 T 06-07-2017 IPR008554 Glutaredoxin-like BWK49_RS25270 176845732b092795c00313a0966a4ebd 89 Gene3D G3DSA:3.40.30.10 9 89 1.0E-18 T 06-07-2017 IPR012336 Thioredoxin-like fold BWK49_RS25270 176845732b092795c00313a0966a4ebd 89 SUPERFAMILY SSF52833 10 87 1.24E-10 T 06-07-2017 IPR012336 Thioredoxin-like fold BWK49_RS15175 691521f70d040f96839338c1534a520c 467 SUPERFAMILY SSF140459 2 174 5.23E-62 T 06-07-2017 BWK49_RS15175 691521f70d040f96839338c1534a520c 467 Pfam PF00823 PPE family 6 161 2.0E-59 T 06-07-2017 IPR000030 PPE family BWK49_RS15175 691521f70d040f96839338c1534a520c 467 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 312 382 1.9E-10 T 06-07-2017 IPR022171 PPE family, C-terminal BWK49_RS16080 c8e0ecb6b4aef744c7285ade6e9e984d 125 PIRSF PIRSF019455 3 125 7.3E-21 T 06-07-2017 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 BWK49_RS16080 c8e0ecb6b4aef744c7285ade6e9e984d 125 Pfam PF03965 Penicillinase repressor 7 116 5.4E-27 T 06-07-2017 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 BWK49_RS16080 c8e0ecb6b4aef744c7285ade6e9e984d 125 SUPERFAMILY SSF46785 5 118 7.44E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS16080 c8e0ecb6b4aef744c7285ade6e9e984d 125 Gene3D G3DSA:1.10.10.10 5 82 1.4E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS22670 8244b958315a31f115b8277793bc6e4d 284 TIGRFAM TIGR02569 TIGR02569_actnb: TIGR02569 family protein 4 280 2.9E-132 T 06-07-2017 IPR013402 Conserved hypothetical protein CHP02569 BWK49_RS07580 c34091bc851c6b6853de03c67b72ed27 257 Gene3D G3DSA:1.10.10.10 157 255 9.4E-34 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS07580 c34091bc851c6b6853de03c67b72ed27 257 Pfam PF00486 Transcriptional regulatory protein, C terminal 180 253 2.4E-25 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 BWK49_RS07580 c34091bc851c6b6853de03c67b72ed27 257 SUPERFAMILY SSF46894 156 254 1.3E-29 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 BWK49_RS07580 c34091bc851c6b6853de03c67b72ed27 257 SMART SM00448 32 143 4.0E-41 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 BWK49_RS07580 c34091bc851c6b6853de03c67b72ed27 257 SUPERFAMILY SSF52172 28 155 2.85E-40 T 06-07-2017 IPR011006 CheY-like superfamily BWK49_RS07580 c34091bc851c6b6853de03c67b72ed27 257 Pfam PF00072 Response regulator receiver domain 34 143 4.8E-27 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 BWK49_RS07580 c34091bc851c6b6853de03c67b72ed27 257 Gene3D G3DSA:3.40.50.2300 25 151 1.3E-39 T 06-07-2017 BWK49_RS07580 c34091bc851c6b6853de03c67b72ed27 257 SMART SM00862 179 253 4.0E-26 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 BWK49_RS08660 09c289c616b8e541adc68157e7531d01 567 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 161 169 - T 06-07-2017 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site BWK49_RS08660 09c289c616b8e541adc68157e7531d01 567 Pfam PF00270 DEAD/DEAH box helicase 37 203 3.6E-48 T 06-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 BWK49_RS08660 09c289c616b8e541adc68157e7531d01 567 Gene3D G3DSA:3.40.50.300 5 213 1.0E-78 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS08660 09c289c616b8e541adc68157e7531d01 567 SMART SM00487 32 230 2.2E-62 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain BWK49_RS08660 09c289c616b8e541adc68157e7531d01 567 SMART SM00490 266 347 5.5E-33 T 06-07-2017 IPR001650 Helicase, C-terminal BWK49_RS08660 09c289c616b8e541adc68157e7531d01 567 Pfam PF00271 Helicase conserved C-terminal domain 239 347 7.0E-28 T 06-07-2017 IPR001650 Helicase, C-terminal BWK49_RS08660 09c289c616b8e541adc68157e7531d01 567 Hamap MF_00964 ATP-dependent RNA helicase DeaD [deaD]. 8 546 43.652 T 06-07-2017 IPR028618 ATP-dependent RNA helicase DeaD GO:0000027|GO:0004004|GO:0070417 BWK49_RS08660 09c289c616b8e541adc68157e7531d01 567 SUPERFAMILY SSF52540 82 368 1.3E-74 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS08660 09c289c616b8e541adc68157e7531d01 567 Pfam PF03880 DbpA RNA binding domain 474 543 1.4E-19 T 06-07-2017 IPR005580 DbpA, RNA-binding domain BWK49_RS08660 09c289c616b8e541adc68157e7531d01 567 Gene3D G3DSA:3.40.50.300 214 379 3.1E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS01395 fc17e0a42371a5b2e7a057a93075afe2 186 SMART SM00953 35 173 4.7E-4 T 06-07-2017 IPR014914 RES domain BWK49_RS01395 fc17e0a42371a5b2e7a057a93075afe2 186 Pfam PF08808 RES domain 25 148 4.4E-15 T 06-07-2017 IPR014914 RES domain BWK49_RS03040 abf8fb241214d1c8c94e9b948d610bb7 307 Pfam PF00561 alpha/beta hydrolase fold 14 290 2.3E-24 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS03040 abf8fb241214d1c8c94e9b948d610bb7 307 Gene3D G3DSA:3.40.50.1820 2 304 6.3E-84 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS03040 abf8fb241214d1c8c94e9b948d610bb7 307 PRINTS PR00412 Epoxide hydrolase signature 20 38 6.8E-32 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS03040 abf8fb241214d1c8c94e9b948d610bb7 307 PRINTS PR00412 Epoxide hydrolase signature 100 113 6.8E-32 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS03040 abf8fb241214d1c8c94e9b948d610bb7 307 PRINTS PR00412 Epoxide hydrolase signature 279 301 6.8E-32 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS03040 abf8fb241214d1c8c94e9b948d610bb7 307 PRINTS PR00412 Epoxide hydrolase signature 245 261 6.8E-32 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS03040 abf8fb241214d1c8c94e9b948d610bb7 307 PRINTS PR00412 Epoxide hydrolase signature 40 55 6.8E-32 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS03040 abf8fb241214d1c8c94e9b948d610bb7 307 PRINTS PR00412 Epoxide hydrolase signature 86 99 6.8E-32 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS03040 abf8fb241214d1c8c94e9b948d610bb7 307 PRINTS PR00111 Alpha/beta hydrolase fold signature 86 99 4.1E-5 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS03040 abf8fb241214d1c8c94e9b948d610bb7 307 PRINTS PR00111 Alpha/beta hydrolase fold signature 100 113 4.1E-5 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS03040 abf8fb241214d1c8c94e9b948d610bb7 307 PRINTS PR00111 Alpha/beta hydrolase fold signature 40 55 4.1E-5 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS03040 abf8fb241214d1c8c94e9b948d610bb7 307 SUPERFAMILY SSF53474 199 304 2.57E-72 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS03040 abf8fb241214d1c8c94e9b948d610bb7 307 SUPERFAMILY SSF53474 1 172 2.57E-72 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS23250 5fbe72248854fce67e91d86f1109fad1 497 Pfam PF00171 Aldehyde dehydrogenase family 22 478 1.6E-131 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 BWK49_RS23250 5fbe72248854fce67e91d86f1109fad1 497 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 251 258 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 BWK49_RS23250 5fbe72248854fce67e91d86f1109fad1 497 SUPERFAMILY SSF53720 22 485 1.57E-134 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 BWK49_RS23250 5fbe72248854fce67e91d86f1109fad1 497 Gene3D G3DSA:3.40.309.10 266 445 3.6E-53 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 BWK49_RS23250 5fbe72248854fce67e91d86f1109fad1 497 Gene3D G3DSA:3.40.605.10 25 265 2.1E-76 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 BWK49_RS11060 22d289db63118002879205d20c28503f 268 SUPERFAMILY SSF52096 6 268 3.87E-62 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS11060 22d289db63118002879205d20c28503f 268 Gene3D G3DSA:3.90.226.10 5 207 1.5E-46 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS11060 22d289db63118002879205d20c28503f 268 Pfam PF00378 Enoyl-CoA hydratase/isomerase 18 267 2.5E-39 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 BWK49_RS11060 22d289db63118002879205d20c28503f 268 Gene3D G3DSA:1.10.12.10 211 268 2.2E-13 T 06-07-2017 IPR014748 Crontonase, C-terminal BWK49_RS25870 21f52d15f5b0b528db50250d8e714b16 252 Pfam PF05690 Thiazole biosynthesis protein ThiG 8 250 1.1E-106 T 06-07-2017 BWK49_RS25870 21f52d15f5b0b528db50250d8e714b16 252 Gene3D G3DSA:3.20.20.70 6 250 1.2E-56 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 BWK49_RS25870 21f52d15f5b0b528db50250d8e714b16 252 Hamap MF_00443 Thiazole synthase [thiG]. 5 252 40.862 T 06-07-2017 IPR008867 Thiazole biosynthesis GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 BWK49_RS25870 21f52d15f5b0b528db50250d8e714b16 252 SUPERFAMILY SSF110399 5 242 5.62E-81 T 06-07-2017 IPR008867 Thiazole biosynthesis GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 BWK49_RS08895 c1900289b78f1209c2c9909f8b3b7b59 311 TIGRFAM TIGR00191 thrB: homoserine kinase 12 274 2.4E-57 T 06-07-2017 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 BWK49_RS08895 c1900289b78f1209c2c9909f8b3b7b59 311 Gene3D G3DSA:3.30.70.890 172 274 2.8E-29 T 06-07-2017 IPR013750 GHMP kinase, C-terminal domain BWK49_RS08895 c1900289b78f1209c2c9909f8b3b7b59 311 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 91 102 - T 06-07-2017 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 BWK49_RS08895 c1900289b78f1209c2c9909f8b3b7b59 311 PIRSF PIRSF000676 5 294 3.0E-79 T 06-07-2017 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 BWK49_RS08895 c1900289b78f1209c2c9909f8b3b7b59 311 PRINTS PR00958 Homoserine kinase signature 136 149 4.7E-37 T 06-07-2017 BWK49_RS08895 c1900289b78f1209c2c9909f8b3b7b59 311 PRINTS PR00958 Homoserine kinase signature 15 30 4.7E-37 T 06-07-2017 BWK49_RS08895 c1900289b78f1209c2c9909f8b3b7b59 311 PRINTS PR00958 Homoserine kinase signature 179 196 4.7E-37 T 06-07-2017 BWK49_RS08895 c1900289b78f1209c2c9909f8b3b7b59 311 PRINTS PR00958 Homoserine kinase signature 256 271 4.7E-37 T 06-07-2017 BWK49_RS08895 c1900289b78f1209c2c9909f8b3b7b59 311 PRINTS PR00958 Homoserine kinase signature 98 113 4.7E-37 T 06-07-2017 BWK49_RS08895 c1900289b78f1209c2c9909f8b3b7b59 311 SUPERFAMILY SSF55060 175 274 3.21E-22 T 06-07-2017 IPR013750 GHMP kinase, C-terminal domain BWK49_RS08895 c1900289b78f1209c2c9909f8b3b7b59 311 Pfam PF00288 GHMP kinases N terminal domain 85 149 5.5E-11 T 06-07-2017 IPR006204 GHMP kinase N-terminal domain GO:0005524 BWK49_RS08895 c1900289b78f1209c2c9909f8b3b7b59 311 SUPERFAMILY SSF54211 9 154 1.14E-26 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold BWK49_RS08895 c1900289b78f1209c2c9909f8b3b7b59 311 Gene3D G3DSA:3.30.230.10 10 157 2.1E-49 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup BWK49_RS08895 c1900289b78f1209c2c9909f8b3b7b59 311 Hamap MF_00384 Homoserine kinase [thrB]. 8 293 27.736 T 06-07-2017 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 BWK49_RS17800 4802f5ccef2ca282d3329f3bea2dff85 323 Gene3D G3DSA:2.40.10.10 125 206 1.8E-14 T 06-07-2017 BWK49_RS17800 4802f5ccef2ca282d3329f3bea2dff85 323 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 146 151 - T 06-07-2017 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 BWK49_RS17800 4802f5ccef2ca282d3329f3bea2dff85 323 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 254 265 - T 06-07-2017 IPR033116 Serine proteases, trypsin family, serine active site BWK49_RS17800 4802f5ccef2ca282d3329f3bea2dff85 323 SUPERFAMILY SSF50494 126 301 9.57E-19 T 06-07-2017 IPR009003 Peptidase S1, PA clan BWK49_RS02360 b8b3365940028e38e27fa47c097dc75b 411 Gene3D G3DSA:1.10.630.10 17 409 5.1E-125 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS02360 b8b3365940028e38e27fa47c097dc75b 411 SUPERFAMILY SSF48264 18 409 1.17E-96 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS02360 b8b3365940028e38e27fa47c097dc75b 411 PRINTS PR00385 P450 superfamily signature 253 270 2.1E-7 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS02360 b8b3365940028e38e27fa47c097dc75b 411 PRINTS PR00385 P450 superfamily signature 288 299 2.1E-7 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS02360 b8b3365940028e38e27fa47c097dc75b 411 PRINTS PR00385 P450 superfamily signature 354 363 2.1E-7 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS02360 b8b3365940028e38e27fa47c097dc75b 411 PRINTS PR00385 P450 superfamily signature 363 374 2.1E-7 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS02360 b8b3365940028e38e27fa47c097dc75b 411 Pfam PF00067 Cytochrome P450 75 384 8.3E-34 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS02360 b8b3365940028e38e27fa47c097dc75b 411 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 356 365 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 BWK49_RS02360 b8b3365940028e38e27fa47c097dc75b 411 PRINTS PR00359 B-class P450 signature 333 348 9.3E-56 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS02360 b8b3365940028e38e27fa47c097dc75b 411 PRINTS PR00359 B-class P450 signature 159 174 9.3E-56 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS02360 b8b3365940028e38e27fa47c097dc75b 411 PRINTS PR00359 B-class P450 signature 142 158 9.3E-56 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS02360 b8b3365940028e38e27fa47c097dc75b 411 PRINTS PR00359 B-class P450 signature 96 107 9.3E-56 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS02360 b8b3365940028e38e27fa47c097dc75b 411 PRINTS PR00359 B-class P450 signature 207 229 9.3E-56 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS02360 b8b3365940028e38e27fa47c097dc75b 411 PRINTS PR00359 B-class P450 signature 288 299 9.3E-56 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS02360 b8b3365940028e38e27fa47c097dc75b 411 PRINTS PR00359 B-class P450 signature 305 332 9.3E-56 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS02360 b8b3365940028e38e27fa47c097dc75b 411 PRINTS PR00359 B-class P450 signature 354 363 9.3E-56 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS02360 b8b3365940028e38e27fa47c097dc75b 411 PRINTS PR00359 B-class P450 signature 363 374 9.3E-56 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS12260 e37ecca17ad8244eb6bfa3fd9869d106 489 Gene3D G3DSA:3.30.200.20 15 114 7.4E-19 T 06-07-2017 BWK49_RS12260 e37ecca17ad8244eb6bfa3fd9869d106 489 Gene3D G3DSA:1.10.510.10 115 263 9.1E-38 T 06-07-2017 BWK49_RS12260 e37ecca17ad8244eb6bfa3fd9869d106 489 SMART SM00220 17 270 2.3E-45 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 BWK49_RS12260 e37ecca17ad8244eb6bfa3fd9869d106 489 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 137 149 - T 06-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 BWK49_RS12260 e37ecca17ad8244eb6bfa3fd9869d106 489 Pfam PF00069 Protein kinase domain 17 216 2.9E-40 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 BWK49_RS12260 e37ecca17ad8244eb6bfa3fd9869d106 489 SUPERFAMILY SSF56112 14 343 2.66E-62 T 06-07-2017 IPR011009 Protein kinase-like domain BWK49_RS15505 357145d34306cd0e3542efbe4afa7340 390 SUPERFAMILY SSF51556 104 388 1.6E-52 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS15505 357145d34306cd0e3542efbe4afa7340 390 SUPERFAMILY SSF51556 37 73 1.6E-52 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS15505 357145d34306cd0e3542efbe4afa7340 390 Gene3D G3DSA:3.20.20.140 56 388 2.5E-40 T 06-07-2017 BWK49_RS15505 357145d34306cd0e3542efbe4afa7340 390 Pfam PF04909 Amidohydrolase 106 388 6.8E-19 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 BWK49_RS27250 de4b99f51b3faf916cae93e40d9ac3b9 537 Pfam PF02470 MlaD protein 47 120 3.3E-12 T 06-07-2017 IPR003399 Mce/MlaD BWK49_RS27250 de4b99f51b3faf916cae93e40d9ac3b9 537 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 15 312 1.7E-90 T 06-07-2017 IPR005693 Virulence factor Mce protein BWK49_RS24190 d833e77ac854c60ec8b4a5cbb0c8b26e 314 Gene3D G3DSA:3.40.50.150 17 225 1.5E-16 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS24190 d833e77ac854c60ec8b4a5cbb0c8b26e 314 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 19 288 7.6E-85 T 06-07-2017 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 BWK49_RS24190 d833e77ac854c60ec8b4a5cbb0c8b26e 314 SUPERFAMILY SSF53335 17 310 3.05E-82 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS24190 d833e77ac854c60ec8b4a5cbb0c8b26e 314 Pfam PF04072 Leucine carboxyl methyltransferase 21 211 1.4E-68 T 06-07-2017 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 BWK49_RS02160 9db1c84432827f7802f360156d51d50c 116 Pfam PF06305 Protein of unknown function (DUF1049) 59 109 2.7E-10 T 06-07-2017 IPR010445 Lipopolysaccharide assembly protein A domain GO:0005887 BWK49_RS07700 69a2a107f038680d2a31db82d6782937 345 Gene3D G3DSA:1.10.12.10 262 319 6.7E-5 T 06-07-2017 IPR014748 Crontonase, C-terminal BWK49_RS07700 69a2a107f038680d2a31db82d6782937 345 Gene3D G3DSA:3.90.226.10 6 199 2.0E-56 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS07700 69a2a107f038680d2a31db82d6782937 345 SUPERFAMILY SSF52096 249 319 4.76E-65 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS07700 69a2a107f038680d2a31db82d6782937 345 SUPERFAMILY SSF52096 3 197 4.76E-65 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS07700 69a2a107f038680d2a31db82d6782937 345 Pfam PF16113 Enoyl-CoA hydratase/isomerase 16 336 7.2E-120 T 06-07-2017 IPR032259 Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type GO:0003860 Reactome: R-HSA-70895 BWK49_RS00475 5eb55cf7d49671b993e9687bf4ec7c0a 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 1 15 2.1E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS00475 5eb55cf7d49671b993e9687bf4ec7c0a 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 2.1E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS00475 5eb55cf7d49671b993e9687bf4ec7c0a 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 2.1E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS00475 5eb55cf7d49671b993e9687bf4ec7c0a 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 2.1E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS00475 5eb55cf7d49671b993e9687bf4ec7c0a 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 226 2.1E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS00475 5eb55cf7d49671b993e9687bf4ec7c0a 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 138 2.1E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS00475 5eb55cf7d49671b993e9687bf4ec7c0a 244 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 135 163 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS00475 5eb55cf7d49671b993e9687bf4ec7c0a 244 Gene3D G3DSA:3.40.50.720 1 243 6.0E-78 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS00475 5eb55cf7d49671b993e9687bf4ec7c0a 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 2.9E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS00475 5eb55cf7d49671b993e9687bf4ec7c0a 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 167 2.9E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS00475 5eb55cf7d49671b993e9687bf4ec7c0a 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 128 136 2.9E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS00475 5eb55cf7d49671b993e9687bf4ec7c0a 244 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 9 241 1.5E-58 T 06-07-2017 BWK49_RS00475 5eb55cf7d49671b993e9687bf4ec7c0a 244 SUPERFAMILY SSF51735 1 243 9.02E-74 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS10950 f676045bc3ec04ae4b0f1ed715a7fe5c 486 Pfam PF00171 Aldehyde dehydrogenase family 19 482 5.1E-144 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 BWK49_RS10950 f676045bc3ec04ae4b0f1ed715a7fe5c 486 SUPERFAMILY SSF53720 7 483 5.24E-145 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 BWK49_RS10950 f676045bc3ec04ae4b0f1ed715a7fe5c 486 Gene3D G3DSA:3.40.605.10 11 266 7.6E-75 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 BWK49_RS10950 f676045bc3ec04ae4b0f1ed715a7fe5c 486 Gene3D G3DSA:3.40.309.10 267 451 4.2E-60 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 BWK49_RS10950 f676045bc3ec04ae4b0f1ed715a7fe5c 486 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 256 263 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 BWK49_RS27495 2fdad71641cde7d9aba59f8280fa4214 182 Gene3D G3DSA:1.20.1260.10 4 158 7.7E-48 T 06-07-2017 IPR012347 Ferritin-related BWK49_RS27495 2fdad71641cde7d9aba59f8280fa4214 182 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 134 152 1.6E-12 T 06-07-2017 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 BWK49_RS27495 2fdad71641cde7d9aba59f8280fa4214 182 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 63 79 1.6E-12 T 06-07-2017 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 BWK49_RS27495 2fdad71641cde7d9aba59f8280fa4214 182 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 39 55 1.6E-12 T 06-07-2017 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 BWK49_RS27495 2fdad71641cde7d9aba59f8280fa4214 182 ProSitePatterns PS00818 Dps protein family signature 1. 39 55 - T 06-07-2017 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 BWK49_RS27495 2fdad71641cde7d9aba59f8280fa4214 182 Pfam PF00210 Ferritin-like domain 19 157 1.7E-27 T 06-07-2017 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 BWK49_RS27495 2fdad71641cde7d9aba59f8280fa4214 182 PIRSF PIRSF005900 1 162 1.9E-54 T 06-07-2017 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 BWK49_RS27495 2fdad71641cde7d9aba59f8280fa4214 182 SUPERFAMILY SSF47240 5 157 5.28E-42 T 06-07-2017 IPR009078 Ferritin-like superfamily BWK49_RS16275 6be19e16d2a758facf5ea41956e4c6d0 610 Pfam PF00361 Proton-conducting membrane transporter 120 399 7.1E-45 T 06-07-2017 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS16275 6be19e16d2a758facf5ea41956e4c6d0 610 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 70 95 1.5E-25 T 06-07-2017 BWK49_RS16275 6be19e16d2a758facf5ea41956e4c6d0 610 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 226 252 1.5E-25 T 06-07-2017 BWK49_RS16275 6be19e16d2a758facf5ea41956e4c6d0 610 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 294 306 1.5E-25 T 06-07-2017 BWK49_RS16275 6be19e16d2a758facf5ea41956e4c6d0 610 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 204 225 1.5E-25 T 06-07-2017 BWK49_RS16275 6be19e16d2a758facf5ea41956e4c6d0 610 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 394 413 1.5E-25 T 06-07-2017 BWK49_RS08045 dc17818082601e2b5646aa5944f08dbb 213 SUPERFAMILY SSF51735 2 203 4.53E-39 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS08045 dc17818082601e2b5646aa5944f08dbb 213 Pfam PF13460 NAD(P)H-binding 8 191 4.0E-46 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS08045 dc17818082601e2b5646aa5944f08dbb 213 Gene3D G3DSA:3.40.50.720 2 206 5.0E-45 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS18860 00e4b075e64486ae961488ecf9e00d8d 143 Pfam PF14042 Domain of unknown function (DUF4247) 21 135 4.5E-26 T 06-07-2017 IPR025341 Protein of unknown function DUF4247 BWK49_RS18860 00e4b075e64486ae961488ecf9e00d8d 143 ProDom PD031728 MEMBRANE PROBABLE RV2599/MT2674 PRECURSOR TRANSMEMBRANE B1177_F3_123 SIGNAL 25 119 2.0E-31 T 06-07-2017 BWK49_RS05745 f42782878660f1d962a4ee3c2da5202f 66 SUPERFAMILY SSF54862 2 58 3.06E-9 T 06-07-2017 BWK49_RS05745 f42782878660f1d962a4ee3c2da5202f 66 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 5 58 2.2E-10 T 06-07-2017 BWK49_RS05745 f42782878660f1d962a4ee3c2da5202f 66 Gene3D G3DSA:3.30.70.20 1 60 2.4E-13 T 06-07-2017 BWK49_RS03620 8b15d8ee0f003e6be2033eb4a8d84439 475 SUPERFAMILY SSF58104 184 293 5.1E-5 T 06-07-2017 BWK49_RS03620 8b15d8ee0f003e6be2033eb4a8d84439 475 Pfam PF02470 MlaD protein 37 110 2.4E-13 T 06-07-2017 IPR003399 Mce/MlaD BWK49_RS03620 8b15d8ee0f003e6be2033eb4a8d84439 475 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 14 300 1.0E-78 T 06-07-2017 IPR005693 Virulence factor Mce protein BWK49_RS11770 35f176f2d3b820df370c25079a5f92d3 268 SUPERFAMILY SSF53474 21 261 9.5E-54 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS11770 35f176f2d3b820df370c25079a5f92d3 268 Gene3D G3DSA:3.40.50.1820 17 261 2.6E-65 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS11770 35f176f2d3b820df370c25079a5f92d3 268 Pfam PF07859 alpha/beta hydrolase fold 39 236 2.8E-54 T 06-07-2017 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 BWK49_RS28000 d5e6104837dcd5d89acd0db6d3ddde70 158 PIRSF PIRSF028065 2 145 4.8E-29 T 06-07-2017 IPR016865 Uncharacterised conserved protein UCP028065, membrane BWK49_RS28000 d5e6104837dcd5d89acd0db6d3ddde70 158 Pfam PF04224 Protein of unknown function, DUF417 4 142 1.0E-21 T 06-07-2017 IPR007339 Protein of unknown function DUF417 BWK49_RS06155 f715809fa6db2bfdacd2d07b8f15374b 304 Pfam PF12697 Alpha/beta hydrolase family 15 249 2.1E-11 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS06155 f715809fa6db2bfdacd2d07b8f15374b 304 Gene3D G3DSA:3.40.50.1820 4 266 8.0E-23 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS06155 f715809fa6db2bfdacd2d07b8f15374b 304 SUPERFAMILY SSF53474 159 264 1.54E-23 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS06155 f715809fa6db2bfdacd2d07b8f15374b 304 SUPERFAMILY SSF53474 10 110 1.54E-23 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS07255 6ac765109b55e903050dbe1f8b3a7019 418 Pfam PF00425 chorismate binding enzyme 152 399 3.5E-68 T 06-07-2017 IPR015890 Chorismate-utilising enzyme, C-terminal BWK49_RS07255 6ac765109b55e903050dbe1f8b3a7019 418 PRINTS PR00095 Anthranilate synthase component I signature 246 259 5.6E-11 T 06-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 BWK49_RS07255 6ac765109b55e903050dbe1f8b3a7019 418 PRINTS PR00095 Anthranilate synthase component I signature 340 354 5.6E-11 T 06-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 BWK49_RS07255 6ac765109b55e903050dbe1f8b3a7019 418 PRINTS PR00095 Anthranilate synthase component I signature 355 369 5.6E-11 T 06-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 BWK49_RS07255 6ac765109b55e903050dbe1f8b3a7019 418 PRINTS PR00095 Anthranilate synthase component I signature 260 273 5.6E-11 T 06-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 BWK49_RS07255 6ac765109b55e903050dbe1f8b3a7019 418 SUPERFAMILY SSF56322 64 405 5.76E-91 T 06-07-2017 IPR005801 ADC synthase GO:0009058 BWK49_RS07255 6ac765109b55e903050dbe1f8b3a7019 418 TIGRFAM TIGR00553 pabB: aminodeoxychorismate synthase, component I 77 403 2.2E-107 T 06-07-2017 IPR005802 Para-aminobenzoate synthase, component I GO:0009396 KEGG: 00790+2.6.1.85|MetaCyc: PWY-6543 BWK49_RS07255 6ac765109b55e903050dbe1f8b3a7019 418 Gene3D G3DSA:3.60.120.10 65 405 4.6E-97 T 06-07-2017 IPR005801 ADC synthase GO:0009058 BWK49_RS16630 5a81915d8c7e796817f70798ffe8c0dc 313 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 8 312 55.303 T 06-07-2017 IPR023009 Tyrosine recombinase XerC/XerD BWK49_RS16630 5a81915d8c7e796817f70798ffe8c0dc 313 Hamap MF_01807 Tyrosine recombinase XerD [xerD]. 6 312 58.378 T 06-07-2017 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 BWK49_RS16630 5a81915d8c7e796817f70798ffe8c0dc 313 Gene3D G3DSA:1.10.443.10 122 304 5.1E-56 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 BWK49_RS16630 5a81915d8c7e796817f70798ffe8c0dc 313 Gene3D G3DSA:1.10.150.130 7 109 2.0E-24 T 06-07-2017 IPR023109 Integrase/recombinase, N-terminal BWK49_RS16630 5a81915d8c7e796817f70798ffe8c0dc 313 Pfam PF00589 Phage integrase family 122 297 2.1E-46 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 BWK49_RS16630 5a81915d8c7e796817f70798ffe8c0dc 313 SUPERFAMILY SSF56349 117 310 3.83E-54 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 BWK49_RS16630 5a81915d8c7e796817f70798ffe8c0dc 313 TIGRFAM TIGR02225 recomb_XerD: tyrosine recombinase XerD 12 312 7.7E-103 T 06-07-2017 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 BWK49_RS16630 5a81915d8c7e796817f70798ffe8c0dc 313 SUPERFAMILY SSF47823 9 105 4.12E-15 T 06-07-2017 IPR010998 Integrase, Lambda-type, N-terminal BWK49_RS16630 5a81915d8c7e796817f70798ffe8c0dc 313 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 10 100 4.2E-25 T 06-07-2017 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 BWK49_RS07525 650681275d697c0ff67ab17b98058a30 162 Pfam PF04417 Protein of unknown function (DUF501) 25 145 9.8E-33 T 06-07-2017 IPR007511 Protein of unknown function DUF501 BWK49_RS05315 f1666b84de166c4293c2afc91becfa75 317 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 8.7E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05315 f1666b84de166c4293c2afc91becfa75 317 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 8.7E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05315 f1666b84de166c4293c2afc91becfa75 317 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 8.7E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05315 f1666b84de166c4293c2afc91becfa75 317 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 8.7E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05315 f1666b84de166c4293c2afc91becfa75 317 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 8.7E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05315 f1666b84de166c4293c2afc91becfa75 317 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 2.9E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05315 f1666b84de166c4293c2afc91becfa75 317 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 2.9E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05315 f1666b84de166c4293c2afc91becfa75 317 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 2.9E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05315 f1666b84de166c4293c2afc91becfa75 317 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 193 0.0045 T 06-07-2017 BWK49_RS05315 f1666b84de166c4293c2afc91becfa75 317 SUPERFAMILY SSF51735 4 277 2.13E-68 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS05315 f1666b84de166c4293c2afc91becfa75 317 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS05315 f1666b84de166c4293c2afc91becfa75 317 Gene3D G3DSA:3.40.50.720 9 246 3.9E-68 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS05315 f1666b84de166c4293c2afc91becfa75 317 Pfam PF00106 short chain dehydrogenase 10 196 1.5E-52 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS16960 39bfb5fd0adcb6af97e36451dd0dff85 397 Gene3D G3DSA:3.90.1150.10 286 391 2.5E-33 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 BWK49_RS16960 39bfb5fd0adcb6af97e36451dd0dff85 397 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 12 392 42.21 T 06-07-2017 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 BWK49_RS16960 39bfb5fd0adcb6af97e36451dd0dff85 397 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 15 391 3.1E-147 T 06-07-2017 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 BWK49_RS16960 39bfb5fd0adcb6af97e36451dd0dff85 397 Gene3D G3DSA:3.40.640.10 58 285 9.6E-88 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 BWK49_RS16960 39bfb5fd0adcb6af97e36451dd0dff85 397 Pfam PF00202 Aminotransferase class-III 21 387 2.6E-107 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 BWK49_RS16960 39bfb5fd0adcb6af97e36451dd0dff85 397 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 219 256 - T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 BWK49_RS16960 39bfb5fd0adcb6af97e36451dd0dff85 397 SUPERFAMILY SSF53383 2 391 2.55E-120 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase BWK49_RS23640 89bd45689cf82c5ed632c0ba7fcb9b4e 347 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 4 313 9.0E-65 T 06-07-2017 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain BWK49_RS23640 89bd45689cf82c5ed632c0ba7fcb9b4e 347 Gene3D G3DSA:3.90.245.10 2 337 8.1E-92 T 06-07-2017 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain BWK49_RS23640 89bd45689cf82c5ed632c0ba7fcb9b4e 347 SUPERFAMILY SSF53590 3 329 1.27E-81 T 06-07-2017 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain BWK49_RS05000 916562127236214a49dd8ce195ddadfd 95 Pfam PF14697 4Fe-4S dicluster domain 12 66 1.4E-10 T 06-07-2017 BWK49_RS05000 916562127236214a49dd8ce195ddadfd 95 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 15 26 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site BWK49_RS05000 916562127236214a49dd8ce195ddadfd 95 SUPERFAMILY SSF54862 9 68 7.48E-17 T 06-07-2017 BWK49_RS05000 916562127236214a49dd8ce195ddadfd 95 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 50 61 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site BWK49_RS05000 916562127236214a49dd8ce195ddadfd 95 Gene3D G3DSA:3.30.70.20 10 66 5.9E-15 T 06-07-2017 BWK49_RS25840 68a2b73a36538593fa6b6a193ab48929 494 Gene3D G3DSA:3.40.630.10 45 107 1.7E-66 T 06-07-2017 BWK49_RS25840 68a2b73a36538593fa6b6a193ab48929 494 Gene3D G3DSA:3.40.630.10 245 470 1.7E-66 T 06-07-2017 BWK49_RS25840 68a2b73a36538593fa6b6a193ab48929 494 Gene3D G3DSA:3.50.30.30 115 231 3.6E-26 T 06-07-2017 BWK49_RS25840 68a2b73a36538593fa6b6a193ab48929 494 Pfam PF02225 PA domain 135 224 6.8E-14 T 06-07-2017 IPR003137 PA domain BWK49_RS25840 68a2b73a36538593fa6b6a193ab48929 494 SUPERFAMILY SSF53187 230 472 1.22E-57 T 06-07-2017 BWK49_RS25840 68a2b73a36538593fa6b6a193ab48929 494 SUPERFAMILY SSF53187 45 96 1.22E-57 T 06-07-2017 BWK49_RS25840 68a2b73a36538593fa6b6a193ab48929 494 SUPERFAMILY SSF52025 122 228 2.22E-14 T 06-07-2017 BWK49_RS25840 68a2b73a36538593fa6b6a193ab48929 494 Pfam PF04389 Peptidase family M28 246 465 4.2E-46 T 06-07-2017 IPR007484 Peptidase M28 BWK49_RS19785 68892876b761f2c5160c599064b0f5c9 302 Pfam PF10118 Predicted metal-dependent hydrolase 25 282 2.6E-74 T 06-07-2017 IPR016516 Uncharacterised conserved protein UCP07580 BWK49_RS19785 68892876b761f2c5160c599064b0f5c9 302 PIRSF PIRSF007580 9 302 2.2E-134 T 06-07-2017 IPR016516 Uncharacterised conserved protein UCP07580 BWK49_RS20845 73d89a31ca7b29ae298e41a890f01571 216 Hamap MF_02114 2-phospho-L-lactate guanylyltransferase [cofC]. 12 216 22.148 T 06-07-2017 IPR002835 2-phospho-L-lactate guanylyltransferase, CofC GO:0016779 KEGG: 00680+2.7.7.68|MetaCyc: PWY-5198 BWK49_RS20845 73d89a31ca7b29ae298e41a890f01571 216 TIGRFAM TIGR03552 F420_cofC: 2-phospho-L-lactate guanylyltransferase 14 209 1.0E-59 T 06-07-2017 IPR002835 2-phospho-L-lactate guanylyltransferase, CofC GO:0016779 KEGG: 00680+2.7.7.68|MetaCyc: PWY-5198 BWK49_RS20845 73d89a31ca7b29ae298e41a890f01571 216 SUPERFAMILY SSF53448 15 209 3.64E-29 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases BWK49_RS20845 73d89a31ca7b29ae298e41a890f01571 216 Pfam PF01983 Guanylyl transferase CofC like 14 150 9.9E-12 T 06-07-2017 IPR002835 2-phospho-L-lactate guanylyltransferase, CofC GO:0016779 KEGG: 00680+2.7.7.68|MetaCyc: PWY-5198 BWK49_RS20845 73d89a31ca7b29ae298e41a890f01571 216 Gene3D G3DSA:3.90.550.10 12 191 1.2E-31 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases BWK49_RS00745 3a327203750575f2c95fab1e5070d6a4 442 Gene3D G3DSA:1.20.1250.20 2 209 4.2E-26 T 06-07-2017 BWK49_RS00745 3a327203750575f2c95fab1e5070d6a4 442 Gene3D G3DSA:1.20.1250.20 232 416 2.8E-19 T 06-07-2017 BWK49_RS00745 3a327203750575f2c95fab1e5070d6a4 442 ProSitePatterns PS00217 Sugar transport proteins signature 2. 115 140 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 BWK49_RS00745 3a327203750575f2c95fab1e5070d6a4 442 ProSitePatterns PS00961 Ribosomal protein S28e signature. 429 437 - T 06-07-2017 IPR028626 Ribosomal protein S28e conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 BWK49_RS00745 3a327203750575f2c95fab1e5070d6a4 442 SUPERFAMILY SSF103473 2 421 2.35E-60 T 06-07-2017 IPR020846 Major facilitator superfamily domain BWK49_RS00745 3a327203750575f2c95fab1e5070d6a4 442 Pfam PF00083 Sugar (and other) transporter 8 421 5.4E-34 T 06-07-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 BWK49_RS15940 c716eefcf1ebbeeff6d2d5200c95af98 602 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 145 157 - T 06-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 BWK49_RS15940 c716eefcf1ebbeeff6d2d5200c95af98 602 SMART SM00220 26 282 4.4E-56 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 BWK49_RS15940 c716eefcf1ebbeeff6d2d5200c95af98 602 Gene3D G3DSA:3.40.30.10 423 594 4.8E-10 T 06-07-2017 IPR012336 Thioredoxin-like fold BWK49_RS15940 c716eefcf1ebbeeff6d2d5200c95af98 602 Gene3D G3DSA:1.10.510.10 123 279 2.1E-43 T 06-07-2017 BWK49_RS15940 c716eefcf1ebbeeff6d2d5200c95af98 602 SUPERFAMILY SSF56112 23 357 3.24E-69 T 06-07-2017 IPR011009 Protein kinase-like domain BWK49_RS15940 c716eefcf1ebbeeff6d2d5200c95af98 602 Pfam PF00069 Protein kinase domain 29 270 3.6E-43 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 BWK49_RS15940 c716eefcf1ebbeeff6d2d5200c95af98 602 Gene3D G3DSA:3.30.200.20 19 122 1.0E-19 T 06-07-2017 BWK49_RS15940 c716eefcf1ebbeeff6d2d5200c95af98 602 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 32 55 - T 06-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 BWK49_RS15940 c716eefcf1ebbeeff6d2d5200c95af98 602 SUPERFAMILY SSF52833 416 598 7.55E-12 T 06-07-2017 IPR012336 Thioredoxin-like fold BWK49_RS15940 c716eefcf1ebbeeff6d2d5200c95af98 602 Pfam PF13462 Thioredoxin 425 567 7.8E-6 T 06-07-2017 IPR012336 Thioredoxin-like fold BWK49_RS25155 8f27028e22c6fb403c17324b2e1c088c 194 SUPERFAMILY SSF52833 66 190 8.12E-25 T 06-07-2017 IPR012336 Thioredoxin-like fold BWK49_RS25155 8f27028e22c6fb403c17324b2e1c088c 194 Gene3D G3DSA:3.40.30.10 4 192 4.0E-30 T 06-07-2017 IPR012336 Thioredoxin-like fold BWK49_RS25155 8f27028e22c6fb403c17324b2e1c088c 194 ProSitePatterns PS00194 Thioredoxin family active site. 80 98 - T 06-07-2017 IPR017937 Thioredoxin, conserved site GO:0045454 BWK49_RS25155 8f27028e22c6fb403c17324b2e1c088c 194 Pfam PF08534 Redoxin 58 179 1.4E-15 T 06-07-2017 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 BWK49_RS26435 66a5d5031808270729b4b2386b2cae97 97 Gene3D G3DSA:1.10.287.1060 1 95 2.7E-13 T 06-07-2017 BWK49_RS26435 66a5d5031808270729b4b2386b2cae97 97 SUPERFAMILY SSF140453 3 92 2.62E-8 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like BWK49_RS26435 66a5d5031808270729b4b2386b2cae97 97 Pfam PF06013 Proteins of 100 residues with WXG 9 87 8.2E-7 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like BWK49_RS04920 412e5c6c5d9aab58b0e3ea65dc8d5ff8 405 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 154 405 2.6E-98 T 06-07-2017 IPR024516 Mammalian cell entry, C-terminal BWK49_RS04920 412e5c6c5d9aab58b0e3ea65dc8d5ff8 405 Pfam PF02470 MlaD protein 44 124 7.1E-12 T 06-07-2017 IPR003399 Mce/MlaD BWK49_RS04920 412e5c6c5d9aab58b0e3ea65dc8d5ff8 405 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 20 302 9.4E-72 T 06-07-2017 IPR005693 Virulence factor Mce protein BWK49_RS01670 4d8a5fa2df5c240d18e41a885ee8054a 223 Pfam PF00665 Integrase core domain 118 192 8.6E-14 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 BWK49_RS01670 4d8a5fa2df5c240d18e41a885ee8054a 223 SUPERFAMILY SSF53098 112 191 1.02E-16 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS01670 4d8a5fa2df5c240d18e41a885ee8054a 223 Gene3D G3DSA:3.30.420.10 113 191 7.9E-15 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS13495 0b3eb0fb07996e06aed1197c0efe9a3d 251 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 76 109 - T 06-07-2017 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 BWK49_RS13495 0b3eb0fb07996e06aed1197c0efe9a3d 251 SUPERFAMILY SSF53790 2 233 4.19E-64 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 BWK49_RS13495 0b3eb0fb07996e06aed1197c0efe9a3d 251 TIGRFAM TIGR01465 cobM_cbiF: precorrin-4 C11-methyltransferase 3 244 3.3E-93 T 06-07-2017 IPR006362 Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase GO:0009236|GO:0046026 BWK49_RS13495 0b3eb0fb07996e06aed1197c0efe9a3d 251 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 6 20 - T 06-07-2017 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 BWK49_RS13495 0b3eb0fb07996e06aed1197c0efe9a3d 251 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 2 209 3.5E-42 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 BWK49_RS13495 0b3eb0fb07996e06aed1197c0efe9a3d 251 Gene3D G3DSA:3.30.950.10 111 232 5.3E-37 T 06-07-2017 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 BWK49_RS13495 0b3eb0fb07996e06aed1197c0efe9a3d 251 Gene3D G3DSA:3.40.1010.10 2 110 6.7E-32 T 06-07-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 BWK49_RS22660 039846040cf947afad00d2d82bea3bde 261 Pfam PF12697 Alpha/beta hydrolase family 18 252 1.2E-18 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS22660 039846040cf947afad00d2d82bea3bde 261 SUPERFAMILY SSF53474 4 258 2.68E-38 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS22660 039846040cf947afad00d2d82bea3bde 261 PRINTS PR00111 Alpha/beta hydrolase fold signature 40 55 4.1E-6 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS22660 039846040cf947afad00d2d82bea3bde 261 PRINTS PR00111 Alpha/beta hydrolase fold signature 83 96 4.1E-6 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS22660 039846040cf947afad00d2d82bea3bde 261 PRINTS PR00111 Alpha/beta hydrolase fold signature 97 110 4.1E-6 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS22660 039846040cf947afad00d2d82bea3bde 261 Gene3D G3DSA:3.40.50.1820 4 258 1.4E-39 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS05285 fa68c1aa9bd7f46e9cfae5aeeb3f6cc7 91 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 3 38 6.3E-10 T 06-07-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM BWK49_RS05285 fa68c1aa9bd7f46e9cfae5aeeb3f6cc7 91 SUPERFAMILY SSF143120 1 48 9.02E-10 T 06-07-2017 BWK49_RS05285 fa68c1aa9bd7f46e9cfae5aeeb3f6cc7 91 Gene3D G3DSA:3.40.1620.10 1 41 1.6E-8 T 06-07-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM BWK49_RS05285 fa68c1aa9bd7f46e9cfae5aeeb3f6cc7 91 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 50 5.9E-11 T 06-07-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM BWK49_RS08480 6c8ba33f3bc5524fae82ce34ed985e17 193 TIGRFAM TIGR00624 tag: DNA-3-methyladenine glycosylase I 7 189 3.7E-87 T 06-07-2017 IPR004597 DNA-3-methyladenine glycosylase I GO:0006284|GO:0008725 BWK49_RS08480 6c8ba33f3bc5524fae82ce34ed985e17 193 Gene3D G3DSA:1.10.340.30 7 188 5.8E-70 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 BWK49_RS08480 6c8ba33f3bc5524fae82ce34ed985e17 193 Pfam PF03352 Methyladenine glycosylase 21 187 1.1E-66 T 06-07-2017 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 BWK49_RS08480 6c8ba33f3bc5524fae82ce34ed985e17 193 SUPERFAMILY SSF48150 7 189 5.76E-65 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 BWK49_RS15725 9bfa088ed7021c854a429037423e99ec 169 SUPERFAMILY SSF54427 3 143 9.21E-30 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS15725 9bfa088ed7021c854a429037423e99ec 169 Pfam PF13577 SnoaL-like domain 12 136 6.7E-25 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain BWK49_RS15725 9bfa088ed7021c854a429037423e99ec 169 Gene3D G3DSA:3.10.450.50 5 150 3.5E-45 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS02770 b7aac481c9d25d654befbbc559269a6d 155 Gene3D G3DSA:3.30.1330.40 6 154 2.5E-66 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like BWK49_RS02770 b7aac481c9d25d654befbbc559269a6d 155 SUPERFAMILY SSF55298 6 154 2.51E-54 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like BWK49_RS02770 b7aac481c9d25d654befbbc559269a6d 155 Pfam PF14588 YjgF/chorismate_mutase-like, putative endoribonuclease 9 154 1.6E-31 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like BWK49_RS27915 e717a50ccc94816f1577e31a9f397bab 231 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 203 0.0043 T 06-07-2017 BWK49_RS27915 e717a50ccc94816f1577e31a9f397bab 231 Gene3D G3DSA:3.40.50.720 2 205 3.5E-46 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS27915 e717a50ccc94816f1577e31a9f397bab 231 Pfam PF00106 short chain dehydrogenase 8 182 1.3E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27915 e717a50ccc94816f1577e31a9f397bab 231 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 123 131 1.4E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27915 e717a50ccc94816f1577e31a9f397bab 231 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 70 81 1.4E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27915 e717a50ccc94816f1577e31a9f397bab 231 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 160 1.4E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27915 e717a50ccc94816f1577e31a9f397bab 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 9.1E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27915 e717a50ccc94816f1577e31a9f397bab 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 117 133 9.1E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27915 e717a50ccc94816f1577e31a9f397bab 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 70 81 9.1E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27915 e717a50ccc94816f1577e31a9f397bab 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 141 160 9.1E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27915 e717a50ccc94816f1577e31a9f397bab 231 SUPERFAMILY SSF51735 1 204 5.16E-47 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS21490 99a1ccbe9dccbfa831d42b853a03c149 107 SUPERFAMILY SSF103481 5 105 7.06E-16 T 06-07-2017 BWK49_RS21490 99a1ccbe9dccbfa831d42b853a03c149 107 Pfam PF00893 Small Multidrug Resistance protein 2 94 1.3E-26 T 06-07-2017 IPR000390 Small multidrug resistance protein family GO:0016021 BWK49_RS22310 d5f192aa7b89290e94e88c3f9c2c292a 229 Gene3D G3DSA:3.30.450.20 25 129 2.6E-16 T 06-07-2017 BWK49_RS22310 d5f192aa7b89290e94e88c3f9c2c292a 229 Pfam PF03861 ANTAR domain 144 194 6.0E-14 T 06-07-2017 IPR005561 ANTAR domain GO:0003723 BWK49_RS22310 d5f192aa7b89290e94e88c3f9c2c292a 229 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 39 130 3.9E-6 T 06-07-2017 IPR000014 PAS domain BWK49_RS22310 d5f192aa7b89290e94e88c3f9c2c292a 229 SMART SM01012 140 195 6.0E-15 T 06-07-2017 IPR005561 ANTAR domain GO:0003723 BWK49_RS22310 d5f192aa7b89290e94e88c3f9c2c292a 229 Pfam PF08447 PAS fold 38 124 1.2E-13 T 06-07-2017 IPR013655 PAS fold-3 GO:0005515 BWK49_RS22310 d5f192aa7b89290e94e88c3f9c2c292a 229 SUPERFAMILY SSF52172 142 194 2.68E-5 T 06-07-2017 IPR011006 CheY-like superfamily BWK49_RS22310 d5f192aa7b89290e94e88c3f9c2c292a 229 Gene3D G3DSA:1.10.10.10 144 196 5.1E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS22310 d5f192aa7b89290e94e88c3f9c2c292a 229 SUPERFAMILY SSF55785 24 129 1.92E-14 T 06-07-2017 IPR000014 PAS domain BWK49_RS08590 561c219ef890a4a579e7b2da43338d2f 392 Gene3D G3DSA:2.40.50.100 240 284 6.7E-7 T 06-07-2017 BWK49_RS08590 561c219ef890a4a579e7b2da43338d2f 392 Gene3D G3DSA:2.40.50.100 370 384 6.7E-7 T 06-07-2017 BWK49_RS08590 561c219ef890a4a579e7b2da43338d2f 392 Pfam PF00005 ABC transporter 21 162 9.8E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 BWK49_RS08590 561c219ef890a4a579e7b2da43338d2f 392 SUPERFAMILY SSF52540 4 243 7.1E-87 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS08590 561c219ef890a4a579e7b2da43338d2f 392 Gene3D G3DSA:3.40.50.300 4 235 1.7E-77 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS08590 561c219ef890a4a579e7b2da43338d2f 392 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 BWK49_RS08590 561c219ef890a4a579e7b2da43338d2f 392 Gene3D G3DSA:2.40.50.140 285 369 4.2E-12 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS08590 561c219ef890a4a579e7b2da43338d2f 392 SUPERFAMILY SSF50331 237 384 2.24E-22 T 06-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal BWK49_RS08590 561c219ef890a4a579e7b2da43338d2f 392 SMART SM00382 29 220 1.5E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS05635 5bc4f58a41a33bc71846a0addff48a7b 411 ProSitePatterns PS01007 Transposases, Mutator family, signature. 233 257 - T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 BWK49_RS05635 5bc4f58a41a33bc71846a0addff48a7b 411 Pfam PF00872 Transposase, Mutator family 7 379 2.7E-147 T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 BWK49_RS10490 45275bb0cbb6ed6f6b689c51c5d0603e 126 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 37 123 4.0E-28 T 06-07-2017 BWK49_RS10490 45275bb0cbb6ed6f6b689c51c5d0603e 126 Pfam PF13827 Domain of unknown function (DUF4189) 37 113 7.3E-15 T 06-07-2017 IPR025240 Domain of unknown function DUF4189 BWK49_RS11805 cc8f12fbc43d83b40ddf064e4a820d74 487 SUPERFAMILY SSF51905 297 340 2.21E-21 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS11805 cc8f12fbc43d83b40ddf064e4a820d74 487 SUPERFAMILY SSF51905 1 191 2.21E-21 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS11805 cc8f12fbc43d83b40ddf064e4a820d74 487 Gene3D G3DSA:3.50.50.60 1 38 1.2E-13 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS11805 cc8f12fbc43d83b40ddf064e4a820d74 487 Gene3D G3DSA:3.50.50.60 70 190 1.2E-13 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS11805 cc8f12fbc43d83b40ddf064e4a820d74 487 Gene3D G3DSA:3.50.50.60 292 335 1.2E-13 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS12745 a7ccaa1bc6b14165e1fda654c62232e5 203 SMART SM00530 14 69 1.7E-9 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 BWK49_RS12745 a7ccaa1bc6b14165e1fda654c62232e5 203 Pfam PF01381 Helix-turn-helix 17 66 4.1E-9 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 BWK49_RS12745 a7ccaa1bc6b14165e1fda654c62232e5 203 Gene3D G3DSA:1.10.260.40 9 75 2.4E-15 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 BWK49_RS12745 a7ccaa1bc6b14165e1fda654c62232e5 203 SUPERFAMILY SSF47413 5 74 2.57E-14 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 BWK49_RS20120 6c3720711baa423c56e9e5c958033384 265 PIRSF PIRSF005650 29 265 9.1E-83 T 06-07-2017 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 BWK49_RS20120 6c3720711baa423c56e9e5c958033384 265 Pfam PF00696 Amino acid kinase family 36 243 1.0E-28 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase BWK49_RS20120 6c3720711baa423c56e9e5c958033384 265 Hamap MF_01220_B Uridylate kinase [pyrH]. 32 264 41.532 T 06-07-2017 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 BWK49_RS20120 6c3720711baa423c56e9e5c958033384 265 Gene3D G3DSA:3.40.1160.10 31 264 1.3E-84 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase BWK49_RS20120 6c3720711baa423c56e9e5c958033384 265 SUPERFAMILY SSF53633 32 264 1.44E-69 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase BWK49_RS20120 6c3720711baa423c56e9e5c958033384 265 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 34 264 9.5E-84 T 06-07-2017 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 BWK49_RS27305 958f6337fb752b8023b9548c4e7c22fd 307 SUPERFAMILY SSF53474 55 299 6.31E-60 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS27305 958f6337fb752b8023b9548c4e7c22fd 307 Pfam PF07859 alpha/beta hydrolase fold 77 279 6.7E-61 T 06-07-2017 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 BWK49_RS27305 958f6337fb752b8023b9548c4e7c22fd 307 Gene3D G3DSA:3.40.50.1820 10 301 2.3E-72 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS03540 1f8da211d936b6dcedb8456f7ba82029 550 Gene3D G3DSA:3.30.300.30 439 534 8.1E-27 T 06-07-2017 BWK49_RS03540 1f8da211d936b6dcedb8456f7ba82029 550 SUPERFAMILY SSF56801 5 537 2.35E-112 T 06-07-2017 BWK49_RS03540 1f8da211d936b6dcedb8456f7ba82029 550 Gene3D G3DSA:3.40.50.980 6 176 5.2E-45 T 06-07-2017 BWK49_RS03540 1f8da211d936b6dcedb8456f7ba82029 550 Pfam PF13193 AMP-binding enzyme C-terminal domain 450 525 5.3E-16 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS03540 1f8da211d936b6dcedb8456f7ba82029 550 Gene3D G3DSA:3.40.50.980 177 349 1.2E-23 T 06-07-2017 BWK49_RS03540 1f8da211d936b6dcedb8456f7ba82029 550 ProSitePatterns PS00455 Putative AMP-binding domain signature. 171 182 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS03540 1f8da211d936b6dcedb8456f7ba82029 550 Gene3D G3DSA:2.30.38.10 362 434 6.4E-7 T 06-07-2017 BWK49_RS03540 1f8da211d936b6dcedb8456f7ba82029 550 Pfam PF00501 AMP-binding enzyme 14 434 2.2E-66 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS23975 b63a6eace33fb4ee08d5713a1b8c61da 457 TIGRFAM TIGR03919 T7SS_EccB: type VII secretion protein EccB 6 442 4.6E-136 T 06-07-2017 IPR007795 Type VII secretion system EccB BWK49_RS23975 b63a6eace33fb4ee08d5713a1b8c61da 457 Pfam PF05108 Type VII secretion system ESX-1, transport TM domain B 3 454 4.8E-136 T 06-07-2017 IPR007795 Type VII secretion system EccB BWK49_RS06785 407c0019072a3cee60fd2a97c0038083 504 Pfam PF03055 Retinal pigment epithelial membrane protein 27 485 2.2E-94 T 06-07-2017 IPR004294 Carotenoid oxygenase GO:0016702|GO:0055114 BWK49_RS10035 fe69fb6524e2efef84bc06aa1480b4dc 292 Gene3D G3DSA:3.40.1190.20 4 290 5.2E-79 T 06-07-2017 IPR029056 Ribokinase-like BWK49_RS10035 fe69fb6524e2efef84bc06aa1480b4dc 292 Hamap MF_01987 Ribokinase [rbsK]. 2 287 22.378 T 06-07-2017 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15 BWK49_RS10035 fe69fb6524e2efef84bc06aa1480b4dc 292 SUPERFAMILY SSF53613 1 288 6.24E-63 T 06-07-2017 IPR029056 Ribokinase-like BWK49_RS10035 fe69fb6524e2efef84bc06aa1480b4dc 292 Pfam PF00294 pfkB family carbohydrate kinase 1 280 4.3E-51 T 06-07-2017 IPR011611 Carbohydrate kinase PfkB BWK49_RS10035 fe69fb6524e2efef84bc06aa1480b4dc 292 PRINTS PR00990 Ribokinase signature 6 27 7.2E-34 T 06-07-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 BWK49_RS10035 fe69fb6524e2efef84bc06aa1480b4dc 292 PRINTS PR00990 Ribokinase signature 199 210 7.2E-34 T 06-07-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 BWK49_RS10035 fe69fb6524e2efef84bc06aa1480b4dc 292 PRINTS PR00990 Ribokinase signature 33 52 7.2E-34 T 06-07-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 BWK49_RS10035 fe69fb6524e2efef84bc06aa1480b4dc 292 PRINTS PR00990 Ribokinase signature 104 117 7.2E-34 T 06-07-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 BWK49_RS10035 fe69fb6524e2efef84bc06aa1480b4dc 292 PRINTS PR00990 Ribokinase signature 174 189 7.2E-34 T 06-07-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 BWK49_RS08450 1e1db86302fb9a80d5a2dafb9426d989 676 SUPERFAMILY SSF52540 1 129 2.28E-8 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS08450 1e1db86302fb9a80d5a2dafb9426d989 676 Gene3D G3DSA:1.25.40.10 517 547 3.7E-4 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 BWK49_RS08450 1e1db86302fb9a80d5a2dafb9426d989 676 Gene3D G3DSA:1.25.40.10 376 473 3.7E-4 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 BWK49_RS08450 1e1db86302fb9a80d5a2dafb9426d989 676 Gene3D G3DSA:3.40.50.300 1 50 2.9E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS08450 1e1db86302fb9a80d5a2dafb9426d989 676 Gene3D G3DSA:3.40.50.300 226 306 2.9E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS06930 468b4664153a0cc7bb06f0faff6534f7 301 SUPERFAMILY SSF47240 28 223 6.49E-11 T 06-07-2017 IPR009078 Ferritin-like superfamily BWK49_RS06930 468b4664153a0cc7bb06f0faff6534f7 301 Pfam PF11583 P-aminobenzoate N-oxygenase AurF 10 285 2.7E-99 T 06-07-2017 IPR025859 P-aminobenzoate N-oxygenase AurF BWK49_RS26370 32c7dd508fae8be6de92ab7823a65b06 219 Pfam PF03734 L,D-transpeptidase catalytic domain 77 215 2.0E-6 T 06-07-2017 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 BWK49_RS12335 32f07f4e942c9adfc60373c5fec78aee 252 SUPERFAMILY SSF53474 43 233 2.86E-42 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS12335 32f07f4e942c9adfc60373c5fec78aee 252 Gene3D G3DSA:3.40.50.1820 43 234 4.5E-55 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS12335 32f07f4e942c9adfc60373c5fec78aee 252 SMART SM01110 42 234 4.5E-92 T 06-07-2017 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 BWK49_RS12335 32f07f4e942c9adfc60373c5fec78aee 252 Pfam PF01083 Cutinase 43 232 9.4E-47 T 06-07-2017 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 BWK49_RS20840 8ebf609f568101f55ad7f12c71545463 347 Gene3D G3DSA:1.10.1040.10 195 345 4.8E-53 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 BWK49_RS20840 8ebf609f568101f55ad7f12c71545463 347 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 12 169 1.7E-49 T 06-07-2017 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 BWK49_RS20840 8ebf609f568101f55ad7f12c71545463 347 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 199 220 - T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 BWK49_RS20840 8ebf609f568101f55ad7f12c71545463 347 PIRSF PIRSF000114 5 347 1.9E-93 T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 BWK49_RS20840 8ebf609f568101f55ad7f12c71545463 347 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 14 31 4.7E-47 T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 BWK49_RS20840 8ebf609f568101f55ad7f12c71545463 347 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 209 233 4.7E-47 T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 BWK49_RS20840 8ebf609f568101f55ad7f12c71545463 347 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 67 94 4.7E-47 T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 BWK49_RS20840 8ebf609f568101f55ad7f12c71545463 347 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 144 164 4.7E-47 T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 BWK49_RS20840 8ebf609f568101f55ad7f12c71545463 347 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 184 208 4.7E-47 T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 BWK49_RS20840 8ebf609f568101f55ad7f12c71545463 347 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 249 266 4.7E-47 T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 BWK49_RS20840 8ebf609f568101f55ad7f12c71545463 347 SUPERFAMILY SSF48179 190 347 9.01E-50 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 BWK49_RS20840 8ebf609f568101f55ad7f12c71545463 347 SUPERFAMILY SSF51735 12 189 3.72E-48 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS20840 8ebf609f568101f55ad7f12c71545463 347 Gene3D G3DSA:3.40.50.720 9 194 5.6E-59 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS20840 8ebf609f568101f55ad7f12c71545463 347 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 10 338 36.732 T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 BWK49_RS20840 8ebf609f568101f55ad7f12c71545463 347 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 191 336 1.6E-47 T 06-07-2017 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 BWK49_RS09305 31b22d179711126669d4ca4ecaa53e6e 276 Gene3D G3DSA:3.20.20.140 9 269 1.1E-47 T 06-07-2017 BWK49_RS09305 31b22d179711126669d4ca4ecaa53e6e 276 Pfam PF04909 Amidohydrolase 42 269 3.2E-30 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 BWK49_RS09305 31b22d179711126669d4ca4ecaa53e6e 276 SUPERFAMILY SSF51556 26 269 9.36E-48 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS00620 283d0ff2d15b8da9fd8a62161248ff40 410 Pfam PF02470 MlaD protein 41 115 2.6E-8 T 06-07-2017 IPR003399 Mce/MlaD BWK49_RS20800 c703b3e4cb0b17ff751a39d85f9643cc 396 Pfam PF13469 Sulfotransferase family 86 340 6.8E-38 T 06-07-2017 BWK49_RS20800 c703b3e4cb0b17ff751a39d85f9643cc 396 Gene3D G3DSA:3.40.50.300 86 123 1.8E-12 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS20800 c703b3e4cb0b17ff751a39d85f9643cc 396 Gene3D G3DSA:3.40.50.300 205 347 1.8E-12 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS20800 c703b3e4cb0b17ff751a39d85f9643cc 396 SUPERFAMILY SSF52540 213 352 9.92E-32 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS20800 c703b3e4cb0b17ff751a39d85f9643cc 396 SUPERFAMILY SSF52540 59 134 9.92E-32 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS06205 561c2e780ac16ce186221f786166a35b 288 SUPERFAMILY SSF53474 3 245 2.81E-28 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS06205 561c2e780ac16ce186221f786166a35b 288 Gene3D G3DSA:3.40.50.1820 3 287 3.1E-26 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS08520 a1d0515f8b2d993981ea71e58406ce2c 222 Gene3D G3DSA:3.40.50.150 27 221 1.8E-50 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS08520 a1d0515f8b2d993981ea71e58406ce2c 222 Pfam PF01596 O-methyltransferase 44 219 6.4E-27 T 06-07-2017 IPR002935 O-methyltransferase, family 3 GO:0008171 BWK49_RS08520 a1d0515f8b2d993981ea71e58406ce2c 222 SUPERFAMILY SSF53335 40 221 5.14E-31 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS00185 ea1855eab21a7345de75df6cc063bb3b 331 SUPERFAMILY SSF51182 41 300 2.8E-65 T 06-07-2017 IPR011051 RmlC-like cupin domain BWK49_RS00185 ea1855eab21a7345de75df6cc063bb3b 331 Pfam PF05726 Pirin C-terminal cupin domain 190 288 6.7E-14 T 06-07-2017 IPR008778 Pirin, C-terminal domain BWK49_RS00185 ea1855eab21a7345de75df6cc063bb3b 331 Gene3D G3DSA:2.60.120.10 32 263 9.0E-58 T 06-07-2017 IPR014710 RmlC-like jelly roll fold BWK49_RS00185 ea1855eab21a7345de75df6cc063bb3b 331 PIRSF PIRSF006232 21 300 1.1E-69 T 06-07-2017 IPR012093 Pirin BWK49_RS00185 ea1855eab21a7345de75df6cc063bb3b 331 Pfam PF02678 Pirin 42 138 7.7E-28 T 06-07-2017 IPR003829 Pirin, N-terminal domain BWK49_RS09665 dc25998d045fa8da232b6eb348cbeca1 412 Gene3D G3DSA:3.30.1050.10 309 401 2.6E-21 T 06-07-2017 IPR003033 SCP2 sterol-binding domain BWK49_RS09665 dc25998d045fa8da232b6eb348cbeca1 412 SUPERFAMILY SSF55729 8 306 1.88E-44 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase BWK49_RS09665 dc25998d045fa8da232b6eb348cbeca1 412 Gene3D G3DSA:3.40.630.30 6 136 2.2E-10 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase BWK49_RS09665 dc25998d045fa8da232b6eb348cbeca1 412 SUPERFAMILY SSF55718 308 409 5.1E-22 T 06-07-2017 IPR003033 SCP2 sterol-binding domain BWK49_RS09665 dc25998d045fa8da232b6eb348cbeca1 412 Pfam PF13530 Sterol carrier protein domain 187 408 4.3E-44 T 06-07-2017 IPR025559 Enhanced intracellular survival protein domain BWK49_RS09665 dc25998d045fa8da232b6eb348cbeca1 412 Gene3D G3DSA:3.40.630.30 153 296 2.2E-27 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase BWK49_RS09665 dc25998d045fa8da232b6eb348cbeca1 412 Pfam PF13527 Acetyltransferase (GNAT) domain 10 139 1.2E-24 T 06-07-2017 BWK49_RS10445 5c29ca2dbf796956344872d70e745a58 1492 ProSitePatterns PS00455 Putative AMP-binding domain signature. 598 609 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS10445 5c29ca2dbf796956344872d70e745a58 1492 Gene3D G3DSA:3.40.50.980 607 765 4.2E-24 T 06-07-2017 BWK49_RS10445 5c29ca2dbf796956344872d70e745a58 1492 SUPERFAMILY SSF52777 189 422 3.89E-42 T 06-07-2017 BWK49_RS10445 5c29ca2dbf796956344872d70e745a58 1492 Gene3D G3DSA:3.40.50.980 455 606 3.4E-39 T 06-07-2017 BWK49_RS10445 5c29ca2dbf796956344872d70e745a58 1492 SMART SM00823 Phosphopantetheine attachment site 961 1029 0.0011 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS10445 5c29ca2dbf796956344872d70e745a58 1492 ProSitePatterns PS00012 Phosphopantetheine attachment site. 985 1000 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site BWK49_RS10445 5c29ca2dbf796956344872d70e745a58 1492 Gene3D G3DSA:3.30.300.30 847 942 3.4E-26 T 06-07-2017 BWK49_RS10445 5c29ca2dbf796956344872d70e745a58 1492 SUPERFAMILY SSF52777 9 202 5.93E-38 T 06-07-2017 BWK49_RS10445 5c29ca2dbf796956344872d70e745a58 1492 SUPERFAMILY SSF56801 449 972 2.49E-122 T 06-07-2017 BWK49_RS10445 5c29ca2dbf796956344872d70e745a58 1492 SUPERFAMILY SSF52777 1216 1485 6.23E-18 T 06-07-2017 BWK49_RS10445 5c29ca2dbf796956344872d70e745a58 1492 SUPERFAMILY SSF52777 1046 1229 9.67E-27 T 06-07-2017 BWK49_RS10445 5c29ca2dbf796956344872d70e745a58 1492 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 483 877 1.9E-105 T 06-07-2017 IPR010071 Amino acid adenylation domain BWK49_RS10445 5c29ca2dbf796956344872d70e745a58 1492 Pfam PF00501 AMP-binding enzyme 461 853 2.3E-76 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS10445 5c29ca2dbf796956344872d70e745a58 1492 Gene3D G3DSA:1.10.1200.10 955 1030 7.9E-17 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS10445 5c29ca2dbf796956344872d70e745a58 1492 Gene3D G3DSA:2.30.38.10 766 842 1.4E-23 T 06-07-2017 BWK49_RS10445 5c29ca2dbf796956344872d70e745a58 1492 SUPERFAMILY SSF47336 955 1026 1.73E-12 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS10445 5c29ca2dbf796956344872d70e745a58 1492 Pfam PF00550 Phosphopantetheine attachment site 963 1025 4.9E-11 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS10445 5c29ca2dbf796956344872d70e745a58 1492 Pfam PF00668 Condensation domain 11 299 3.1E-52 T 06-07-2017 IPR001242 Condensation domain BWK49_RS10445 5c29ca2dbf796956344872d70e745a58 1492 Pfam PF00668 Condensation domain 1060 1335 8.2E-21 T 06-07-2017 IPR001242 Condensation domain BWK49_RS10445 5c29ca2dbf796956344872d70e745a58 1492 Pfam PF13193 AMP-binding enzyme C-terminal domain 861 933 8.8E-9 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS17780 9303fb14b992c8ec4996cef738ab6f4e 323 TIGRFAM TIGR00750 lao: LAO/AO transport system ATPase 13 318 5.3E-126 T 06-07-2017 IPR005129 SIMIBI class G3E GTPase, ArgK/MeaB GO:0003924|GO:0005525 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 BWK49_RS17780 9303fb14b992c8ec4996cef738ab6f4e 323 SUPERFAMILY SSF52540 4 318 8.81E-90 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS17780 9303fb14b992c8ec4996cef738ab6f4e 323 Gene3D G3DSA:3.40.50.300 51 254 5.7E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS17780 9303fb14b992c8ec4996cef738ab6f4e 323 Gene3D G3DSA:1.20.5.170 1 50 2.6E-19 T 06-07-2017 BWK49_RS17780 9303fb14b992c8ec4996cef738ab6f4e 323 Pfam PF03308 ArgK protein 18 290 5.6E-116 T 06-07-2017 BWK49_RS01760 cdb4e8f17b6c27b236946753aef0f599 343 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 287 332 - T 06-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 BWK49_RS01760 cdb4e8f17b6c27b236946753aef0f599 343 Gene3D G3DSA:1.10.10.60 234 286 1.4E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS01760 cdb4e8f17b6c27b236946753aef0f599 343 SUPERFAMILY SSF46689 234 284 4.19E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS01760 cdb4e8f17b6c27b236946753aef0f599 343 Pfam PF14525 AraC-binding-like domain 34 213 2.8E-38 T 06-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 BWK49_RS01760 cdb4e8f17b6c27b236946753aef0f599 343 Pfam PF12833 Helix-turn-helix domain 256 337 2.3E-24 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 BWK49_RS01760 cdb4e8f17b6c27b236946753aef0f599 343 SMART SM00342 250 336 5.4E-27 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 BWK49_RS01760 cdb4e8f17b6c27b236946753aef0f599 343 SUPERFAMILY SSF46689 290 337 4.66E-5 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS01760 cdb4e8f17b6c27b236946753aef0f599 343 Gene3D G3DSA:1.10.10.60 287 334 2.2E-6 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS10250 ceae9fdd670e568d1eb0bd7eebc25fe2 247 Hamap MF_00063 Phosphoadenosine phosphosulfate reductase [cysH]. 5 246 36.71 T 06-07-2017 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 BWK49_RS10250 ceae9fdd670e568d1eb0bd7eebc25fe2 247 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 55 221 2.3E-44 T 06-07-2017 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 BWK49_RS10250 ceae9fdd670e568d1eb0bd7eebc25fe2 247 TIGRFAM TIGR02055 APS_reductase: adenylylsulfate reductase, thioredoxin dependent 58 244 4.0E-71 T 06-07-2017 IPR011798 Adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019344|GO:0055114 KEGG: 00920+1.8.4.8 BWK49_RS10250 ceae9fdd670e568d1eb0bd7eebc25fe2 247 Gene3D G3DSA:3.40.50.620 6 218 8.6E-53 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold BWK49_RS10250 ceae9fdd670e568d1eb0bd7eebc25fe2 247 SUPERFAMILY SSF52402 23 208 5.44E-40 T 06-07-2017 BWK49_RS10250 ceae9fdd670e568d1eb0bd7eebc25fe2 247 PIRSF PIRSF000857 1 247 1.9E-82 T 06-07-2017 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 BWK49_RS10250 ceae9fdd670e568d1eb0bd7eebc25fe2 247 TIGRFAM TIGR00434 cysH: phosophoadenylyl-sulfate reductase 53 245 3.6E-53 T 06-07-2017 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 BWK49_RS07870 68153313f601d7d1a33135c972d2647a 415 Pfam PF13742 OB-fold nucleic acid binding domain 18 110 4.1E-14 T 06-07-2017 IPR025824 OB-fold nucleic acid binding domain GO:0003676 BWK49_RS07870 68153313f601d7d1a33135c972d2647a 415 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 10 409 25.302 T 06-07-2017 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 BWK49_RS07870 68153313f601d7d1a33135c972d2647a 415 Pfam PF02601 Exonuclease VII, large subunit 326 406 1.8E-8 T 06-07-2017 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 BWK49_RS07870 68153313f601d7d1a33135c972d2647a 415 Pfam PF02601 Exonuclease VII, large subunit 134 353 9.4E-63 T 06-07-2017 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 BWK49_RS07870 68153313f601d7d1a33135c972d2647a 415 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 18 406 1.5E-112 T 06-07-2017 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 BWK49_RS10930 8d521667880e0489fe0f413d902fee35 191 SUPERFAMILY SSF54637 27 186 2.24E-18 T 06-07-2017 IPR029069 HotDog domain BWK49_RS10930 8d521667880e0489fe0f413d902fee35 191 Gene3D G3DSA:3.10.129.10 28 181 2.8E-21 T 06-07-2017 IPR029069 HotDog domain BWK49_RS10930 8d521667880e0489fe0f413d902fee35 191 Pfam PF13452 N-terminal half of MaoC dehydratase 32 171 1.6E-19 T 06-07-2017 BWK49_RS15525 77ff9fda951e6562aaaccec5756e6d94 87 Pfam PF12587 Protein of unknown function (DUF3761) 10 85 1.6E-12 T 06-07-2017 IPR022236 Protein of unknown function DUF3761 BWK49_RS15525 77ff9fda951e6562aaaccec5756e6d94 87 SUPERFAMILY SSF57184 29 70 8.3E-5 T 06-07-2017 IPR009030 Growth factor receptor cysteine-rich domain BWK49_RS27265 0d0cfa262afd7969e471816b37132f8e 435 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 16 303 3.6E-76 T 06-07-2017 IPR005693 Virulence factor Mce protein BWK49_RS27265 0d0cfa262afd7969e471816b37132f8e 435 Pfam PF02470 MlaD protein 45 124 6.7E-13 T 06-07-2017 IPR003399 Mce/MlaD BWK49_RS27265 0d0cfa262afd7969e471816b37132f8e 435 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 154 435 5.0E-106 T 06-07-2017 IPR024516 Mammalian cell entry, C-terminal BWK49_RS18560 f3be7df73aada7500411997b8bbe941f 369 SUPERFAMILY SSF53092 5 134 4.71E-26 T 06-07-2017 IPR028980 Creatinase/Aminopeptidase P, N-terminal BWK49_RS18560 f3be7df73aada7500411997b8bbe941f 369 SUPERFAMILY SSF55920 136 368 1.44E-69 T 06-07-2017 IPR000994 Peptidase M24, structural domain BWK49_RS18560 f3be7df73aada7500411997b8bbe941f 369 Gene3D G3DSA:3.40.350.10 4 134 9.5E-25 T 06-07-2017 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal BWK49_RS18560 f3be7df73aada7500411997b8bbe941f 369 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 294 306 - T 06-07-2017 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site BWK49_RS18560 f3be7df73aada7500411997b8bbe941f 369 Gene3D G3DSA:3.90.230.10 136 367 2.2E-74 T 06-07-2017 IPR000994 Peptidase M24, structural domain BWK49_RS18560 f3be7df73aada7500411997b8bbe941f 369 Pfam PF00557 Metallopeptidase family M24 144 347 5.3E-60 T 06-07-2017 IPR000994 Peptidase M24, structural domain BWK49_RS18560 f3be7df73aada7500411997b8bbe941f 369 Pfam PF01321 Creatinase/Prolidase N-terminal domain 6 136 3.7E-26 T 06-07-2017 IPR000587 Creatinase, N-terminal GO:0016787 BWK49_RS03305 275525b0027846c7c59e11020028c2c2 314 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 95 1.0E-9 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS03305 275525b0027846c7c59e11020028c2c2 314 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 182 313 1.6E-22 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS03305 275525b0027846c7c59e11020028c2c2 314 SUPERFAMILY SSF56645 3 121 2.68E-14 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS03305 275525b0027846c7c59e11020028c2c2 314 Gene3D G3DSA:1.10.540.10 2 97 1.6E-10 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS03305 275525b0027846c7c59e11020028c2c2 314 Gene3D G3DSA:1.20.140.10 184 313 1.4E-29 T 06-07-2017 BWK49_RS03305 275525b0027846c7c59e11020028c2c2 314 SUPERFAMILY SSF47203 183 313 1.77E-33 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS16725 d724b47c9995b8283cb8d890ce6d93af 1015 Pfam PF00501 AMP-binding enzyme 468 888 1.6E-32 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS16725 d724b47c9995b8283cb8d890ce6d93af 1015 Gene3D G3DSA:3.40.50.980 661 780 1.4E-10 T 06-07-2017 BWK49_RS16725 d724b47c9995b8283cb8d890ce6d93af 1015 Gene3D G3DSA:3.40.50.1820 65 373 1.3E-24 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS16725 d724b47c9995b8283cb8d890ce6d93af 1015 SUPERFAMILY SSF53474 66 373 7.54E-30 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS16725 d724b47c9995b8283cb8d890ce6d93af 1015 Gene3D G3DSA:3.40.50.980 463 611 1.2E-17 T 06-07-2017 BWK49_RS16725 d724b47c9995b8283cb8d890ce6d93af 1015 SUPERFAMILY SSF56801 462 979 4.71E-47 T 06-07-2017 BWK49_RS26805 6e0c66b618f9f1e7ed3f5064c11a1563 358 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 1 216 1.5E-60 T 06-07-2017 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 BWK49_RS26805 6e0c66b618f9f1e7ed3f5064c11a1563 358 PIRSF PIRSF000267 1 344 3.9E-99 T 06-07-2017 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 BWK49_RS26805 6e0c66b618f9f1e7ed3f5064c11a1563 358 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 1 331 4.7E-98 T 06-07-2017 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 BWK49_RS03575 e6a24f2d3880bcbaff9e4f0d8525f49c 365 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 10 118 1.2E-9 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS03575 e6a24f2d3880bcbaff9e4f0d8525f49c 365 Gene3D G3DSA:2.40.110.10 134 213 6.5E-9 T 06-07-2017 BWK49_RS03575 e6a24f2d3880bcbaff9e4f0d8525f49c 365 SUPERFAMILY SSF56645 1 213 6.54E-30 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS03575 e6a24f2d3880bcbaff9e4f0d8525f49c 365 SUPERFAMILY SSF47203 214 360 7.09E-31 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS03575 e6a24f2d3880bcbaff9e4f0d8525f49c 365 Gene3D G3DSA:1.20.140.10 216 362 2.1E-31 T 06-07-2017 BWK49_RS03575 e6a24f2d3880bcbaff9e4f0d8525f49c 365 Gene3D G3DSA:1.10.540.10 1 119 1.1E-15 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS03575 e6a24f2d3880bcbaff9e4f0d8525f49c 365 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 223 359 5.5E-23 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS15590 842fdcfcce29e8acf4e206550c9a73b0 341 SUPERFAMILY SSF51412 109 306 1.19E-47 T 06-07-2017 BWK49_RS15590 842fdcfcce29e8acf4e206550c9a73b0 341 SUPERFAMILY SSF51412 4 72 1.19E-47 T 06-07-2017 BWK49_RS15590 842fdcfcce29e8acf4e206550c9a73b0 341 Gene3D G3DSA:3.20.20.70 4 326 1.7E-54 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 BWK49_RS15590 842fdcfcce29e8acf4e206550c9a73b0 341 Pfam PF03060 Nitronate monooxygenase 12 338 6.0E-71 T 06-07-2017 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 BWK49_RS28290 c222ccb9ce5d01bcd636d465eda84f75 169 SUPERFAMILY SSF103647 18 69 1.44E-5 T 06-07-2017 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 BWK49_RS28290 c222ccb9ce5d01bcd636d465eda84f75 169 Gene3D G3DSA:4.10.1080.10 106 165 3.0E-8 T 06-07-2017 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 BWK49_RS28290 c222ccb9ce5d01bcd636d465eda84f75 169 SUPERFAMILY SSF103647 101 165 1.18E-10 T 06-07-2017 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 BWK49_RS19095 18588c1eaf2459ecbbb67bc5ff2bc189 514 Pfam PF00501 AMP-binding enzyme 15 414 2.9E-91 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS19095 18588c1eaf2459ecbbb67bc5ff2bc189 514 Gene3D G3DSA:2.30.38.10 331 404 3.0E-26 T 06-07-2017 BWK49_RS19095 18588c1eaf2459ecbbb67bc5ff2bc189 514 Pfam PF13193 AMP-binding enzyme C-terminal domain 423 496 3.3E-23 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS19095 18588c1eaf2459ecbbb67bc5ff2bc189 514 Gene3D G3DSA:3.40.50.980 169 320 2.7E-33 T 06-07-2017 BWK49_RS19095 18588c1eaf2459ecbbb67bc5ff2bc189 514 ProSitePatterns PS00455 Putative AMP-binding domain signature. 163 174 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS19095 18588c1eaf2459ecbbb67bc5ff2bc189 514 Gene3D G3DSA:3.30.300.30 411 509 2.5E-30 T 06-07-2017 BWK49_RS19095 18588c1eaf2459ecbbb67bc5ff2bc189 514 SUPERFAMILY SSF56801 8 508 2.09E-143 T 06-07-2017 BWK49_RS19095 18588c1eaf2459ecbbb67bc5ff2bc189 514 Gene3D G3DSA:3.40.50.980 8 168 9.0E-35 T 06-07-2017 BWK49_RS06695 df358d59ebe2ff0fd1d2ca8fe768ad3e 209 PIRSF PIRSF000190 4 209 2.0E-71 T 06-07-2017 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 BWK49_RS06695 df358d59ebe2ff0fd1d2ca8fe768ad3e 209 Hamap MF_01629 Pyridoxine/pyridoxamine 5'-phosphate oxidase [pdxH]. 4 209 35.537 T 06-07-2017 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 BWK49_RS06695 df358d59ebe2ff0fd1d2ca8fe768ad3e 209 Pfam PF10590 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region 173 209 4.3E-14 T 06-07-2017 IPR019576 Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 BWK49_RS06695 df358d59ebe2ff0fd1d2ca8fe768ad3e 209 SUPERFAMILY SSF50475 13 209 3.73E-63 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 BWK49_RS06695 df358d59ebe2ff0fd1d2ca8fe768ad3e 209 TIGRFAM TIGR00558 pdxH: pyridoxamine 5'-phosphate oxidase 21 199 5.4E-64 T 06-07-2017 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 BWK49_RS06695 df358d59ebe2ff0fd1d2ca8fe768ad3e 209 Gene3D G3DSA:2.30.110.10 16 199 3.4E-73 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 BWK49_RS06695 df358d59ebe2ff0fd1d2ca8fe768ad3e 209 ProSitePatterns PS01064 Pyridoxamine 5'-phosphate oxidase signature. 183 196 - T 06-07-2017 IPR019740 Pyridoxamine 5'-phosphate oxidase, conserved site GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 BWK49_RS06695 df358d59ebe2ff0fd1d2ca8fe768ad3e 209 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 33 118 2.4E-23 T 06-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 BWK49_RS04110 f3fc602b926e568944d9782128f116d1 144 SUPERFAMILY SSF52833 42 143 1.68E-24 T 06-07-2017 IPR012336 Thioredoxin-like fold BWK49_RS04110 f3fc602b926e568944d9782128f116d1 144 Pfam PF00085 Thioredoxin 54 139 4.9E-13 T 06-07-2017 IPR013766 Thioredoxin domain GO:0045454 BWK49_RS04110 f3fc602b926e568944d9782128f116d1 144 Gene3D G3DSA:3.40.30.10 2 59 7.3E-4 T 06-07-2017 IPR012336 Thioredoxin-like fold BWK49_RS04110 f3fc602b926e568944d9782128f116d1 144 Gene3D G3DSA:3.40.30.10 60 143 6.1E-21 T 06-07-2017 IPR012336 Thioredoxin-like fold BWK49_RS04110 f3fc602b926e568944d9782128f116d1 144 ProSitePatterns PS00194 Thioredoxin family active site. 56 74 - T 06-07-2017 IPR017937 Thioredoxin, conserved site GO:0045454 BWK49_RS23705 19679e69afe24e7f84fcbfa66caaaa32 191 Gene3D G3DSA:1.20.1290.10 42 167 3.4E-18 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 BWK49_RS23705 19679e69afe24e7f84fcbfa66caaaa32 191 SUPERFAMILY SSF69118 1 167 8.43E-20 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 BWK49_RS15660 f75e276b14795a3408441e7c067d6300 400 Gene3D G3DSA:3.40.47.10 157 197 3.5E-10 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS15660 f75e276b14795a3408441e7c067d6300 400 Gene3D G3DSA:3.40.47.10 258 384 3.5E-10 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS15660 f75e276b14795a3408441e7c067d6300 400 SUPERFAMILY SSF53901 9 243 9.02E-13 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS15660 f75e276b14795a3408441e7c067d6300 400 Gene3D G3DSA:3.40.47.10 30 116 2.2E-4 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS15660 f75e276b14795a3408441e7c067d6300 400 Gene3D G3DSA:3.40.47.10 208 236 2.2E-4 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS15660 f75e276b14795a3408441e7c067d6300 400 PIRSF PIRSF000429 5 396 2.7E-15 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 BWK49_RS15660 f75e276b14795a3408441e7c067d6300 400 SUPERFAMILY SSF53901 248 389 5.19E-22 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS12860 8ae2e82d167d1b552d6f80d6c6b1f69b 324 Gene3D G3DSA:3.40.1190.20 2 306 6.0E-50 T 06-07-2017 IPR029056 Ribokinase-like BWK49_RS12860 8ae2e82d167d1b552d6f80d6c6b1f69b 324 SUPERFAMILY SSF53613 2 298 6.24E-57 T 06-07-2017 IPR029056 Ribokinase-like BWK49_RS12860 8ae2e82d167d1b552d6f80d6c6b1f69b 324 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 47 71 - T 06-07-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 BWK49_RS12860 8ae2e82d167d1b552d6f80d6c6b1f69b 324 Pfam PF00294 pfkB family carbohydrate kinase 30 295 8.5E-54 T 06-07-2017 IPR011611 Carbohydrate kinase PfkB BWK49_RS27120 d3140d450c1b9287f2e4d2a6b5221829 346 Pfam PF03734 L,D-transpeptidase catalytic domain 205 327 2.9E-17 T 06-07-2017 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 BWK49_RS27120 d3140d450c1b9287f2e4d2a6b5221829 346 SUPERFAMILY SSF141523 200 327 9.02E-27 T 06-07-2017 BWK49_RS27120 d3140d450c1b9287f2e4d2a6b5221829 346 Gene3D G3DSA:2.40.440.10 206 328 4.0E-18 T 06-07-2017 BWK49_RS02260 00e66b6be66bfe1f200913f9e8dd384e 316 Gene3D G3DSA:3.20.20.30 9 315 1.8E-53 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS02260 00e66b6be66bfe1f200913f9e8dd384e 316 SUPERFAMILY SSF51679 11 314 9.29E-46 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS02260 00e66b6be66bfe1f200913f9e8dd384e 316 Pfam PF00296 Luciferase-like monooxygenase 14 233 9.6E-25 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS08795 96638eb07d70813bf270d5019b5faa6b 163 Gene3D G3DSA:3.40.1050.10 4 161 6.2E-37 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 BWK49_RS08795 96638eb07d70813bf270d5019b5faa6b 163 SMART SM00947 23 162 3.0E-29 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 BWK49_RS08795 96638eb07d70813bf270d5019b5faa6b 163 Pfam PF00484 Carbonic anhydrase 31 129 1.1E-12 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 BWK49_RS08795 96638eb07d70813bf270d5019b5faa6b 163 SUPERFAMILY SSF53056 4 161 1.7E-39 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 BWK49_RS11565 a5dc6f2c0f25282a108434011be947df 310 TIGRFAM TIGR01136 cysKM: cysteine synthase 8 305 7.9E-135 T 06-07-2017 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 BWK49_RS11565 a5dc6f2c0f25282a108434011be947df 310 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 06-07-2017 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 BWK49_RS11565 a5dc6f2c0f25282a108434011be947df 310 TIGRFAM TIGR01139 cysK: cysteine synthase A 8 305 1.8E-141 T 06-07-2017 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 BWK49_RS11565 a5dc6f2c0f25282a108434011be947df 310 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 8 294 6.6E-72 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme BWK49_RS11565 a5dc6f2c0f25282a108434011be947df 310 SUPERFAMILY SSF53686 2 306 5.24E-108 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme BWK49_RS11565 a5dc6f2c0f25282a108434011be947df 310 Gene3D G3DSA:3.40.50.1100 135 307 2.4E-80 T 06-07-2017 BWK49_RS11565 a5dc6f2c0f25282a108434011be947df 310 Gene3D G3DSA:3.40.50.1100 38 134 6.6E-41 T 06-07-2017 BWK49_RS02795 94bd5018902908088dfee19ab5290a6b 215 Pfam PF08534 Redoxin 83 195 4.0E-12 T 06-07-2017 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 BWK49_RS02795 94bd5018902908088dfee19ab5290a6b 215 SUPERFAMILY SSF52833 89 203 4.92E-21 T 06-07-2017 IPR012336 Thioredoxin-like fold BWK49_RS02795 94bd5018902908088dfee19ab5290a6b 215 Gene3D G3DSA:3.40.30.10 69 210 3.8E-25 T 06-07-2017 IPR012336 Thioredoxin-like fold BWK49_RS02795 94bd5018902908088dfee19ab5290a6b 215 Gene3D G3DSA:3.40.30.10 6 30 3.8E-25 T 06-07-2017 IPR012336 Thioredoxin-like fold BWK49_RS02795 94bd5018902908088dfee19ab5290a6b 215 ProSitePatterns PS00194 Thioredoxin family active site. 106 124 - T 06-07-2017 IPR017937 Thioredoxin, conserved site GO:0045454 BWK49_RS15670 a9a75b8759e27b74c785e23d9521913b 166 SUPERFAMILY SSF54637 14 165 2.93E-21 T 06-07-2017 IPR029069 HotDog domain BWK49_RS15670 a9a75b8759e27b74c785e23d9521913b 166 Gene3D G3DSA:3.10.129.10 14 165 4.1E-25 T 06-07-2017 IPR029069 HotDog domain BWK49_RS15670 a9a75b8759e27b74c785e23d9521913b 166 Pfam PF13452 N-terminal half of MaoC dehydratase 15 156 8.8E-19 T 06-07-2017 BWK49_RS23995 e44853e61ad8bb087e0994627220899e 214 Pfam PF01196 Ribosomal protein L17 20 116 2.3E-37 T 06-07-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS23995 e44853e61ad8bb087e0994627220899e 214 SUPERFAMILY SSF64263 1 117 9.03E-48 T 06-07-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS23995 e44853e61ad8bb087e0994627220899e 214 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 5 116 27.066 T 06-07-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS23995 e44853e61ad8bb087e0994627220899e 214 Gene3D G3DSA:3.90.1030.10 3 116 1.9E-47 T 06-07-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS23995 e44853e61ad8bb087e0994627220899e 214 ProSitePatterns PS01167 Ribosomal protein L17 signature. 34 56 - T 06-07-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS23995 e44853e61ad8bb087e0994627220899e 214 TIGRFAM TIGR00059 L17: ribosomal protein bL17 8 116 3.4E-42 T 06-07-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS06870 511e5d6f6eec88a5644c4a7f3582a44a 370 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 51 369 3.6E-109 T 06-07-2017 IPR005673 ABC transporter, phosphate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 BWK49_RS06870 511e5d6f6eec88a5644c4a7f3582a44a 370 PIRSF PIRSF002756 6 370 1.1E-109 T 06-07-2017 IPR005673 ABC transporter, phosphate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 BWK49_RS06870 511e5d6f6eec88a5644c4a7f3582a44a 370 Gene3D G3DSA:3.40.190.10 211 369 3.9E-19 T 06-07-2017 BWK49_RS06870 511e5d6f6eec88a5644c4a7f3582a44a 370 Gene3D G3DSA:3.40.190.10 50 197 1.5E-45 T 06-07-2017 BWK49_RS06870 511e5d6f6eec88a5644c4a7f3582a44a 370 SUPERFAMILY SSF53850 51 370 6.79E-84 T 06-07-2017 BWK49_RS06870 511e5d6f6eec88a5644c4a7f3582a44a 370 Pfam PF12849 PBP superfamily domain 46 336 8.2E-57 T 06-07-2017 IPR024370 PBP domain BWK49_RS10345 726f253b8d886b32c2dfc19d70890356 389 Gene3D G3DSA:3.40.50.300 111 239 5.3E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS10345 726f253b8d886b32c2dfc19d70890356 389 Pfam PF05621 Bacterial TniB protein 126 356 2.0E-19 T 06-07-2017 IPR008868 Bacterial TniB BWK49_RS10345 726f253b8d886b32c2dfc19d70890356 389 SUPERFAMILY SSF52540 118 252 7.53E-10 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS19630 795339447655d0a7f9a96104b6dca3fc 204 Pfam PF01066 CDP-alcohol phosphatidyltransferase 26 96 9.6E-14 T 06-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 BWK49_RS19630 795339447655d0a7f9a96104b6dca3fc 204 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 74 96 - T 06-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 BWK49_RS19630 795339447655d0a7f9a96104b6dca3fc 204 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 26 199 2.2E-41 T 06-07-2017 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668 BWK49_RS19630 795339447655d0a7f9a96104b6dca3fc 204 PIRSF PIRSF000847 22 204 2.5E-47 T 06-07-2017 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668 BWK49_RS00150 56d022b264b9dcab56477e470c5dd3e2 152 Gene3D G3DSA:1.20.120.450 12 150 3.7E-13 T 06-07-2017 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase BWK49_RS00150 56d022b264b9dcab56477e470c5dd3e2 152 SUPERFAMILY SSF109854 6 152 2.29E-22 T 06-07-2017 BWK49_RS00150 56d022b264b9dcab56477e470c5dd3e2 152 Pfam PF12867 DinB superfamily 17 146 2.0E-15 T 06-07-2017 IPR024775 DinB-like domain BWK49_RS13420 da75476a3402d60da769f869d64476c7 255 Hamap MF_00289_B Proteasome subunit alpha [prcA]. 1 237 47.48 T 06-07-2017 IPR022296 Proteasome, alpha subunit, bacterial GO:0004298|GO:0019773|GO:0051603 BWK49_RS13420 da75476a3402d60da769f869d64476c7 255 Gene3D G3DSA:3.60.20.10 3 243 5.8E-85 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal BWK49_RS13420 da75476a3402d60da769f869d64476c7 255 Pfam PF00227 Proteasome subunit 25 205 3.2E-40 T 06-07-2017 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5687128|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-983168 BWK49_RS13420 da75476a3402d60da769f869d64476c7 255 SUPERFAMILY SSF56235 10 235 3.66E-47 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal BWK49_RS13420 da75476a3402d60da769f869d64476c7 255 TIGRFAM TIGR03691 20S_bact_alpha: proteasome, alpha subunit 2 233 5.2E-115 T 06-07-2017 IPR022296 Proteasome, alpha subunit, bacterial GO:0004298|GO:0019773|GO:0051603 BWK49_RS19040 9cc69d56e507f675671f639301ce3d83 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 3.7E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS19040 9cc69d56e507f675671f639301ce3d83 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 3.7E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS19040 9cc69d56e507f675671f639301ce3d83 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 3.7E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS19040 9cc69d56e507f675671f639301ce3d83 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 3.7E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS19040 9cc69d56e507f675671f639301ce3d83 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 3.7E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS19040 9cc69d56e507f675671f639301ce3d83 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 3.7E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS19040 9cc69d56e507f675671f639301ce3d83 272 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS19040 9cc69d56e507f675671f639301ce3d83 272 Pfam PF00106 short chain dehydrogenase 8 195 6.8E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS19040 9cc69d56e507f675671f639301ce3d83 272 Gene3D G3DSA:3.40.50.720 2 260 2.9E-58 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS19040 9cc69d56e507f675671f639301ce3d83 272 SUPERFAMILY SSF51735 1 259 3.81E-55 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS27660 d95f9c22119bf2428d101a00b30ff95c 959 SUPERFAMILY SSF82866 151 347 3.53E-25 T 06-07-2017 BWK49_RS27660 d95f9c22119bf2428d101a00b30ff95c 959 SUPERFAMILY SSF82866 717 926 4.84E-22 T 06-07-2017 BWK49_RS27660 d95f9c22119bf2428d101a00b30ff95c 959 Pfam PF03176 MMPL family 599 934 2.3E-94 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 BWK49_RS27660 d95f9c22119bf2428d101a00b30ff95c 959 Pfam PF03176 MMPL family 51 379 2.7E-103 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 BWK49_RS27660 d95f9c22119bf2428d101a00b30ff95c 959 TIGRFAM TIGR00833 actII: transport protein 17 926 3.1E-304 T 06-07-2017 IPR004707 Membrane transport protein MmpL family GO:0016021 BWK49_RS27660 d95f9c22119bf2428d101a00b30ff95c 959 Gene3D G3DSA:1.20.1640.10 726 929 6.3E-24 T 06-07-2017 BWK49_RS27660 d95f9c22119bf2428d101a00b30ff95c 959 Gene3D G3DSA:1.20.1640.10 151 352 3.1E-23 T 06-07-2017 BWK49_RS11265 8f187d7cfda51ee9f3c93b3b51d3b3d8 365 SUPERFAMILY SSF54862 304 363 1.38E-8 T 06-07-2017 BWK49_RS11265 8f187d7cfda51ee9f3c93b3b51d3b3d8 365 Gene3D G3DSA:3.30.70.20 303 364 9.3E-14 T 06-07-2017 BWK49_RS11265 8f187d7cfda51ee9f3c93b3b51d3b3d8 365 Gene3D G3DSA:3.20.20.70 4 293 2.5E-43 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 BWK49_RS11265 8f187d7cfda51ee9f3c93b3b51d3b3d8 365 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 307 363 2.4E-11 T 06-07-2017 BWK49_RS11265 8f187d7cfda51ee9f3c93b3b51d3b3d8 365 Pfam PF05853 beta-keto acid cleavage enzyme 8 292 4.5E-48 T 06-07-2017 IPR008567 3-keto-5-aminohexanoate cleavage enzyme GO:0016740|GO:0019475 KEGG: 00600+2.3.1.24 BWK49_RS09460 4c768e12601e6962b50b1756e35dbe06 410 Gene3D G3DSA:1.10.630.10 7 408 8.3E-112 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS09460 4c768e12601e6962b50b1756e35dbe06 410 PRINTS PR00359 B-class P450 signature 278 289 1.6E-36 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS09460 4c768e12601e6962b50b1756e35dbe06 410 PRINTS PR00359 B-class P450 signature 344 353 1.6E-36 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS09460 4c768e12601e6962b50b1756e35dbe06 410 PRINTS PR00359 B-class P450 signature 295 322 1.6E-36 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS09460 4c768e12601e6962b50b1756e35dbe06 410 PRINTS PR00359 B-class P450 signature 160 175 1.6E-36 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS09460 4c768e12601e6962b50b1756e35dbe06 410 PRINTS PR00359 B-class P450 signature 197 219 1.6E-36 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS09460 4c768e12601e6962b50b1756e35dbe06 410 PRINTS PR00359 B-class P450 signature 323 338 1.6E-36 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS09460 4c768e12601e6962b50b1756e35dbe06 410 PRINTS PR00359 B-class P450 signature 353 364 1.6E-36 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS09460 4c768e12601e6962b50b1756e35dbe06 410 PRINTS PR00359 B-class P450 signature 143 159 1.6E-36 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS09460 4c768e12601e6962b50b1756e35dbe06 410 SUPERFAMILY SSF48264 10 408 5.5E-92 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS09460 4c768e12601e6962b50b1756e35dbe06 410 Pfam PF00067 Cytochrome P450 175 372 1.9E-27 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS12605 bb77b13f3a58f6b4afe10e73a3590154 388 SUPERFAMILY SSF51445 46 344 2.78E-58 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily BWK49_RS12605 bb77b13f3a58f6b4afe10e73a3590154 388 Gene3D G3DSA:3.20.20.80 46 355 6.1E-68 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 BWK49_RS13905 dc1bbb5748e593afc4f5c076da5a4938 138 Pfam PF05423 Mycobacterium membrane protein 2 138 1.4E-53 T 06-07-2017 IPR008693 Transport accessory protein MmpS BWK49_RS11775 bd6b28e5ac2ecf7bbffde34dbc571049 401 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 207 392 3.1E-22 T 06-07-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 BWK49_RS11775 bd6b28e5ac2ecf7bbffde34dbc571049 401 Gene3D G3DSA:3.90.380.10 175 241 9.3E-5 T 06-07-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 BWK49_RS11775 bd6b28e5ac2ecf7bbffde34dbc571049 401 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 86 101 2.2E-6 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS11775 bd6b28e5ac2ecf7bbffde34dbc571049 401 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 127 147 2.2E-6 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS11775 bd6b28e5ac2ecf7bbffde34dbc571049 401 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 204 226 2.2E-6 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS11775 bd6b28e5ac2ecf7bbffde34dbc571049 401 Gene3D G3DSA:2.102.10.10 71 174 2.1E-27 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS11775 bd6b28e5ac2ecf7bbffde34dbc571049 401 Pfam PF00355 Rieske [2Fe-2S] domain 78 153 2.6E-16 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS11775 bd6b28e5ac2ecf7bbffde34dbc571049 401 SUPERFAMILY SSF55961 187 394 5.57E-27 T 06-07-2017 BWK49_RS11775 bd6b28e5ac2ecf7bbffde34dbc571049 401 SUPERFAMILY SSF50022 40 183 4.32E-36 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS14385 6158177c2385dcc637abf10d8b43b559 286 SUPERFAMILY SSF52096 41 281 1.38E-61 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS14385 6158177c2385dcc637abf10d8b43b559 286 Pfam PF00378 Enoyl-CoA hydratase/isomerase 47 280 1.5E-44 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 BWK49_RS14385 6158177c2385dcc637abf10d8b43b559 286 Gene3D G3DSA:3.90.226.10 40 281 6.6E-61 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS27685 112ab864194ace212f601a06db644f2f 349 Pfam PF00756 Putative esterase 61 322 1.4E-70 T 06-07-2017 IPR000801 Putative esterase Reactome: R-HSA-156590 BWK49_RS27685 112ab864194ace212f601a06db644f2f 349 SUPERFAMILY SSF53474 47 326 9.63E-39 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS27685 112ab864194ace212f601a06db644f2f 349 Gene3D G3DSA:3.40.50.1820 50 326 2.2E-119 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS13265 d6c9cf1a90bbe22ee17815fb087a1825 481 PIRSF PIRSF006060 5 478 8.1E-62 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 BWK49_RS13265 d6c9cf1a90bbe22ee17815fb087a1825 481 Pfam PF00324 Amino acid permease 32 468 1.4E-102 T 06-07-2017 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 BWK49_RS13265 d6c9cf1a90bbe22ee17815fb087a1825 481 ProSitePatterns PS00218 Amino acid permeases signature. 56 86 - T 06-07-2017 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 BWK49_RS07150 58e2bd42437864945733cd64da9b70c2 207 SUPERFAMILY SSF51735 4 191 8.97E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS07150 58e2bd42437864945733cd64da9b70c2 207 Gene3D G3DSA:3.40.50.720 4 194 5.5E-45 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS07150 58e2bd42437864945733cd64da9b70c2 207 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 4 93 1.0E-14 T 06-07-2017 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal BWK49_RS19945 41431d9018b105fb2c332863534604cc 582 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 4 568 2.8E-161 T 06-07-2017 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 BWK49_RS19945 41431d9018b105fb2c332863534604cc 582 Pfam PF03129 Anticodon binding domain 491 566 4.0E-13 T 06-07-2017 IPR004154 Anticodon-binding BWK49_RS19945 41431d9018b105fb2c332863534604cc 582 Hamap MF_01569 Proline--tRNA ligase [proS]. 3 581 35.887 T 06-07-2017 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 BWK49_RS19945 41431d9018b105fb2c332863534604cc 582 SUPERFAMILY SSF55826 281 391 1.96E-10 T 06-07-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 BWK49_RS19945 41431d9018b105fb2c332863534604cc 582 SUPERFAMILY SSF52954 476 567 3.76E-23 T 06-07-2017 IPR004154 Anticodon-binding BWK49_RS19945 41431d9018b105fb2c332863534604cc 582 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 96 471 3.1E-35 T 06-07-2017 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 BWK49_RS19945 41431d9018b105fb2c332863534604cc 582 PRINTS PR01046 Prolyl-tRNA synthetase signature 146 157 1.5E-14 T 06-07-2017 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 BWK49_RS19945 41431d9018b105fb2c332863534604cc 582 PRINTS PR01046 Prolyl-tRNA synthetase signature 70 88 1.5E-14 T 06-07-2017 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 BWK49_RS19945 41431d9018b105fb2c332863534604cc 582 PRINTS PR01046 Prolyl-tRNA synthetase signature 136 144 1.5E-14 T 06-07-2017 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 BWK49_RS19945 41431d9018b105fb2c332863534604cc 582 PRINTS PR01046 Prolyl-tRNA synthetase signature 106 117 1.5E-14 T 06-07-2017 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 BWK49_RS19945 41431d9018b105fb2c332863534604cc 582 Pfam PF04073 Aminoacyl-tRNA editing domain 262 391 1.7E-21 T 06-07-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 BWK49_RS19945 41431d9018b105fb2c332863534604cc 582 SUPERFAMILY SSF55681 419 489 1.47E-85 T 06-07-2017 BWK49_RS19945 41431d9018b105fb2c332863534604cc 582 SUPERFAMILY SSF55681 12 239 1.47E-85 T 06-07-2017 BWK49_RS19945 41431d9018b105fb2c332863534604cc 582 Gene3D G3DSA:3.40.50.800 480 566 2.9E-19 T 06-07-2017 IPR004154 Anticodon-binding BWK49_RS19945 41431d9018b105fb2c332863534604cc 582 Gene3D G3DSA:3.30.930.10 404 479 2.0E-91 T 06-07-2017 BWK49_RS19945 41431d9018b105fb2c332863534604cc 582 Gene3D G3DSA:3.30.930.10 8 206 2.0E-91 T 06-07-2017 BWK49_RS19945 41431d9018b105fb2c332863534604cc 582 Gene3D G3DSA:3.90.960.10 280 393 9.2E-8 T 06-07-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 BWK49_RS18550 f912e08a54cc8a92ae48d58225526edb 169 Hamap MF_00073 N utilization substance protein B homolog [nusB]. 6 141 21.828 T 06-07-2017 IPR011605 NusB antitermination factor GO:0006353 BWK49_RS18550 f912e08a54cc8a92ae48d58225526edb 169 Pfam PF01029 NusB family 9 136 3.1E-34 T 06-07-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 BWK49_RS18550 f912e08a54cc8a92ae48d58225526edb 169 SUPERFAMILY SSF48013 8 136 6.93E-39 T 06-07-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 BWK49_RS18550 f912e08a54cc8a92ae48d58225526edb 169 Gene3D G3DSA:1.10.940.10 5 136 3.2E-41 T 06-07-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 BWK49_RS18550 f912e08a54cc8a92ae48d58225526edb 169 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 8 137 1.6E-37 T 06-07-2017 IPR011605 NusB antitermination factor GO:0006353 BWK49_RS27290 566db7deb3d98be85bf191307c3eceb0 146 Gene3D G3DSA:3.30.530.20 1 143 9.2E-16 T 06-07-2017 IPR023393 START-like domain BWK49_RS27290 566db7deb3d98be85bf191307c3eceb0 146 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 10 136 2.1E-9 T 06-07-2017 IPR005031 Coenzyme Q-binding protein COQ10, START domain BWK49_RS27290 566db7deb3d98be85bf191307c3eceb0 146 SUPERFAMILY SSF55961 1 145 2.01E-22 T 06-07-2017 BWK49_RS02475 6d458f6d4acd03d277b219e494c2c3b8 474 SUPERFAMILY SSF56176 49 185 3.78E-28 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 BWK49_RS02475 6d458f6d4acd03d277b219e494c2c3b8 474 SUPERFAMILY SSF55103 161 463 1.02E-12 T 06-07-2017 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 BWK49_RS02475 6d458f6d4acd03d277b219e494c2c3b8 474 Pfam PF01565 FAD binding domain 50 153 1.4E-10 T 06-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 BWK49_RS02475 6d458f6d4acd03d277b219e494c2c3b8 474 Gene3D G3DSA:3.30.465.10 71 180 3.0E-11 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 BWK49_RS25560 d157e8ec5b2517f873ec721c48a5dea4 976 TIGRFAM TIGR00833 actII: transport protein 27 935 6.9E-304 T 06-07-2017 IPR004707 Membrane transport protein MmpL family GO:0016021 BWK49_RS25560 d157e8ec5b2517f873ec721c48a5dea4 976 SUPERFAMILY SSF82866 159 355 4.58E-27 T 06-07-2017 BWK49_RS25560 d157e8ec5b2517f873ec721c48a5dea4 976 Gene3D G3DSA:1.20.1640.10 158 357 7.0E-26 T 06-07-2017 BWK49_RS25560 d157e8ec5b2517f873ec721c48a5dea4 976 Gene3D G3DSA:1.20.1640.10 745 939 1.7E-25 T 06-07-2017 BWK49_RS25560 d157e8ec5b2517f873ec721c48a5dea4 976 Pfam PF03176 MMPL family 59 388 1.8E-111 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 BWK49_RS25560 d157e8ec5b2517f873ec721c48a5dea4 976 Pfam PF03176 MMPL family 628 943 2.4E-95 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 BWK49_RS25560 d157e8ec5b2517f873ec721c48a5dea4 976 SUPERFAMILY SSF82866 726 935 1.83E-30 T 06-07-2017 BWK49_RS24975 0f31169e7dfb07188f939446aee9f69c 565 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 230 248 8.2E-7 T 06-07-2017 BWK49_RS24975 0f31169e7dfb07188f939446aee9f69c 565 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 67 86 8.2E-7 T 06-07-2017 BWK49_RS24975 0f31169e7dfb07188f939446aee9f69c 565 SUPERFAMILY SSF51905 65 294 1.08E-50 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS24975 0f31169e7dfb07188f939446aee9f69c 565 Gene3D G3DSA:3.50.50.60 347 529 1.5E-10 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS24975 0f31169e7dfb07188f939446aee9f69c 565 Gene3D G3DSA:3.50.50.60 63 274 4.6E-57 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS24975 0f31169e7dfb07188f939446aee9f69c 565 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 226 250 1.5E-12 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 BWK49_RS24975 0f31169e7dfb07188f939446aee9f69c 565 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 188 196 1.5E-12 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 BWK49_RS24975 0f31169e7dfb07188f939446aee9f69c 565 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 66 88 1.5E-12 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 BWK49_RS24975 0f31169e7dfb07188f939446aee9f69c 565 SUPERFAMILY SSF51905 320 517 1.08E-18 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS24975 0f31169e7dfb07188f939446aee9f69c 565 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 69 270 7.2E-18 T 06-07-2017 BWK49_RS24195 8f71c68e55314ca580cd75d09429edf9 302 Pfam PF04072 Leucine carboxyl methyltransferase 21 202 1.9E-63 T 06-07-2017 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 BWK49_RS24195 8f71c68e55314ca580cd75d09429edf9 302 Gene3D G3DSA:3.40.50.150 16 224 2.8E-16 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS24195 8f71c68e55314ca580cd75d09429edf9 302 SUPERFAMILY SSF53335 17 291 7.36E-80 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS24195 8f71c68e55314ca580cd75d09429edf9 302 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 19 277 4.5E-82 T 06-07-2017 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 BWK49_RS28360 8317a3f044d6f0bf21a98acecc189a45 322 Pfam PF13614 AAA domain 69 247 7.9E-58 T 06-07-2017 IPR025669 AAA domain BWK49_RS28360 8317a3f044d6f0bf21a98acecc189a45 322 SUPERFAMILY SSF52540 69 321 4.73E-66 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS28360 8317a3f044d6f0bf21a98acecc189a45 322 Gene3D G3DSA:3.40.50.300 70 321 1.5E-71 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS02420 4b3120cc5bafe8c578775ff01af1b794 328 SUPERFAMILY SSF51735 1 321 8.36E-50 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS02420 4b3120cc5bafe8c578775ff01af1b794 328 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 182 4.1E-20 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 BWK49_RS02420 4b3120cc5bafe8c578775ff01af1b794 328 Gene3D G3DSA:3.40.50.720 1 320 3.9E-43 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS26895 85567417ef893637ca46e04f5fff5dc8 340 Pfam PF16864 Dimerisation domain 15 89 1.1E-6 T 06-07-2017 IPR031725 Acetylserotonin O-methyltransferase, dimerisation domain BWK49_RS26895 85567417ef893637ca46e04f5fff5dc8 340 PIRSF PIRSF005739 6 340 6.9E-51 T 06-07-2017 IPR016461 O-methyltransferase COMT-type GO:0008168 BWK49_RS26895 85567417ef893637ca46e04f5fff5dc8 340 SUPERFAMILY SSF46785 12 95 2.78E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS26895 85567417ef893637ca46e04f5fff5dc8 340 Gene3D G3DSA:1.10.10.10 10 98 4.1E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS26895 85567417ef893637ca46e04f5fff5dc8 340 SUPERFAMILY SSF53335 96 337 2.63E-52 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS26895 85567417ef893637ca46e04f5fff5dc8 340 Gene3D G3DSA:3.40.50.150 99 339 1.4E-68 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS26895 85567417ef893637ca46e04f5fff5dc8 340 Pfam PF00891 O-methyltransferase 110 321 1.1E-50 T 06-07-2017 IPR001077 O-methyltransferase, family 2 GO:0008171 BWK49_RS22520 04e488e91ab7bdb275eebcc5643145b3 378 SUPERFAMILY SSF51905 10 202 1.68E-43 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS22520 04e488e91ab7bdb275eebcc5643145b3 378 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 13 195 2.0E-26 T 06-07-2017 BWK49_RS22520 04e488e91ab7bdb275eebcc5643145b3 378 SUPERFAMILY SSF51905 147 316 1.85E-11 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS22520 04e488e91ab7bdb275eebcc5643145b3 378 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 12 31 4.4E-10 T 06-07-2017 BWK49_RS22520 04e488e91ab7bdb275eebcc5643145b3 378 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 168 186 4.4E-10 T 06-07-2017 BWK49_RS22520 04e488e91ab7bdb275eebcc5643145b3 378 Gene3D G3DSA:3.50.50.60 12 176 9.9E-47 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS22520 04e488e91ab7bdb275eebcc5643145b3 378 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 129 138 1.5E-12 T 06-07-2017 BWK49_RS22520 04e488e91ab7bdb275eebcc5643145b3 378 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 11 33 1.5E-12 T 06-07-2017 BWK49_RS22520 04e488e91ab7bdb275eebcc5643145b3 378 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 168 193 1.5E-12 T 06-07-2017 BWK49_RS22520 04e488e91ab7bdb275eebcc5643145b3 378 Gene3D G3DSA:3.50.50.60 276 315 1.8E-6 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS22520 04e488e91ab7bdb275eebcc5643145b3 378 Gene3D G3DSA:3.50.50.60 177 217 1.8E-6 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS15530 27814baeb0f145a77d05f934a395c317 147 Pfam PF05305 Protein of unknown function (DUF732) 38 132 1.8E-13 T 06-07-2017 IPR007969 Domain of unknown function DUF732 BWK49_RS07360 35c108d587eaa50306790beb46bfcf76 411 SUPERFAMILY SSF140459 3 175 3.66E-62 T 06-07-2017 BWK49_RS07360 35c108d587eaa50306790beb46bfcf76 411 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 331 405 1.6E-13 T 06-07-2017 IPR022171 PPE family, C-terminal BWK49_RS07360 35c108d587eaa50306790beb46bfcf76 411 Pfam PF00823 PPE family 6 162 3.3E-62 T 06-07-2017 IPR000030 PPE family BWK49_RS05895 111b85fe47dc1de87a42e834e96e7c81 225 Pfam PF09339 IclR helix-turn-helix domain 10 58 1.7E-10 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 BWK49_RS05895 111b85fe47dc1de87a42e834e96e7c81 225 SMART SM00346 8 95 1.7E-16 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 BWK49_RS05895 111b85fe47dc1de87a42e834e96e7c81 225 Gene3D G3DSA:3.30.450.40 81 224 2.2E-21 T 06-07-2017 IPR029016 GAF domain-like BWK49_RS05895 111b85fe47dc1de87a42e834e96e7c81 225 SUPERFAMILY SSF46785 9 79 2.49E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS05895 111b85fe47dc1de87a42e834e96e7c81 225 SUPERFAMILY SSF55781 70 224 3.27E-23 T 06-07-2017 IPR029016 GAF domain-like BWK49_RS05895 111b85fe47dc1de87a42e834e96e7c81 225 Gene3D G3DSA:1.10.10.10 7 80 1.3E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS14535 4de877382c69f192b49b8c2313e3d8f9 410 Pfam PF00144 Beta-lactamase 25 384 9.9E-59 T 06-07-2017 IPR001466 Beta-lactamase-related BWK49_RS14535 4de877382c69f192b49b8c2313e3d8f9 410 SUPERFAMILY SSF56601 17 399 9.73E-62 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like BWK49_RS14535 4de877382c69f192b49b8c2313e3d8f9 410 Gene3D G3DSA:3.40.710.10 264 399 1.7E-67 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like BWK49_RS14535 4de877382c69f192b49b8c2313e3d8f9 410 Gene3D G3DSA:3.40.710.10 21 224 1.7E-67 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like BWK49_RS24335 9c06c5c14c60f18160bf7952d7f2ef58 420 Pfam PF00067 Cytochrome P450 225 396 2.8E-23 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS24335 9c06c5c14c60f18160bf7952d7f2ef58 420 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 362 371 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 BWK49_RS24335 9c06c5c14c60f18160bf7952d7f2ef58 420 PRINTS PR00359 B-class P450 signature 169 184 2.3E-45 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS24335 9c06c5c14c60f18160bf7952d7f2ef58 420 PRINTS PR00359 B-class P450 signature 360 369 2.3E-45 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS24335 9c06c5c14c60f18160bf7952d7f2ef58 420 PRINTS PR00359 B-class P450 signature 152 168 2.3E-45 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS24335 9c06c5c14c60f18160bf7952d7f2ef58 420 PRINTS PR00359 B-class P450 signature 311 338 2.3E-45 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS24335 9c06c5c14c60f18160bf7952d7f2ef58 420 PRINTS PR00359 B-class P450 signature 105 116 2.3E-45 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS24335 9c06c5c14c60f18160bf7952d7f2ef58 420 PRINTS PR00359 B-class P450 signature 369 380 2.3E-45 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS24335 9c06c5c14c60f18160bf7952d7f2ef58 420 PRINTS PR00359 B-class P450 signature 294 305 2.3E-45 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS24335 9c06c5c14c60f18160bf7952d7f2ef58 420 PRINTS PR00359 B-class P450 signature 213 235 2.3E-45 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS24335 9c06c5c14c60f18160bf7952d7f2ef58 420 PRINTS PR00359 B-class P450 signature 339 354 2.3E-45 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS24335 9c06c5c14c60f18160bf7952d7f2ef58 420 SUPERFAMILY SSF48264 27 420 5.11E-88 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS24335 9c06c5c14c60f18160bf7952d7f2ef58 420 Gene3D G3DSA:1.10.630.10 21 417 1.2E-109 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS24335 9c06c5c14c60f18160bf7952d7f2ef58 420 PRINTS PR00385 P450 superfamily signature 259 276 5.5E-6 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS24335 9c06c5c14c60f18160bf7952d7f2ef58 420 PRINTS PR00385 P450 superfamily signature 360 369 5.5E-6 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS24335 9c06c5c14c60f18160bf7952d7f2ef58 420 PRINTS PR00385 P450 superfamily signature 369 380 5.5E-6 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS14460 f11f2cb0795d4cbc29116b93b8b11e92 284 SUPERFAMILY SSF69593 31 174 1.02E-11 T 06-07-2017 BWK49_RS14460 f11f2cb0795d4cbc29116b93b8b11e92 284 SUPERFAMILY SSF69593 204 262 1.02E-11 T 06-07-2017 BWK49_RS14460 f11f2cb0795d4cbc29116b93b8b11e92 284 Pfam PF01553 Acyltransferase 42 168 1.8E-7 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 BWK49_RS14460 f11f2cb0795d4cbc29116b93b8b11e92 284 SMART SM00563 54 171 0.0026 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 BWK49_RS18935 e11ccf533123717ad5462f0f10cfd619 217 SUPERFAMILY SSF54637 22 211 6.51E-39 T 06-07-2017 IPR029069 HotDog domain BWK49_RS18935 e11ccf533123717ad5462f0f10cfd619 217 Gene3D G3DSA:3.10.129.10 70 215 1.8E-31 T 06-07-2017 IPR029069 HotDog domain BWK49_RS18935 e11ccf533123717ad5462f0f10cfd619 217 Pfam PF03061 Thioesterase superfamily 127 202 1.7E-7 T 06-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 BWK49_RS26980 450547bfc086ec8a87b2a44d79cf04cb 401 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 221 236 - T 06-07-2017 IPR019826 Carboxylesterase type B, active site BWK49_RS26980 450547bfc086ec8a87b2a44d79cf04cb 401 Pfam PF07859 alpha/beta hydrolase fold 157 366 1.2E-21 T 06-07-2017 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 BWK49_RS26980 450547bfc086ec8a87b2a44d79cf04cb 401 SUPERFAMILY SSF53474 113 368 1.87E-48 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS26980 450547bfc086ec8a87b2a44d79cf04cb 401 Gene3D G3DSA:3.40.50.1820 128 374 9.5E-62 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS07830 7e790b950a56bab84dc6c621935ae73a 328 TIGRFAM TIGR00330 glpX: fructose-1,6-bisphosphatase, class II 1 309 2.9E-108 T 06-07-2017 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 BWK49_RS07830 7e790b950a56bab84dc6c621935ae73a 328 SUPERFAMILY SSF56655 2 307 1.44E-109 T 06-07-2017 BWK49_RS07830 7e790b950a56bab84dc6c621935ae73a 328 Gene3D G3DSA:3.30.540.10 1 167 5.2E-60 T 06-07-2017 BWK49_RS07830 7e790b950a56bab84dc6c621935ae73a 328 Gene3D G3DSA:3.30.540.10 168 316 2.9E-44 T 06-07-2017 BWK49_RS07830 7e790b950a56bab84dc6c621935ae73a 328 Pfam PF03320 Bacterial fructose-1,6-bisphosphatase, glpX-encoded 1 304 9.9E-138 T 06-07-2017 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 BWK49_RS07830 7e790b950a56bab84dc6c621935ae73a 328 PIRSF PIRSF004532 1 315 3.5E-149 T 06-07-2017 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 BWK49_RS08635 54733a2f277a558741bd314e6b3f5da3 1240 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 112 344 2.8E-54 T 06-07-2017 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 BWK49_RS08635 54733a2f277a558741bd314e6b3f5da3 1240 SMART SM00861 889 1088 5.0E-47 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain BWK49_RS08635 54733a2f277a558741bd314e6b3f5da3 1240 Gene3D G3DSA:3.30.559.10 101 344 2.6E-49 T 06-07-2017 IPR023213 Chloramphenicol acetyltransferase-like domain Reactome: R-HSA-389661 BWK49_RS08635 54733a2f277a558741bd314e6b3f5da3 1240 Gene3D G3DSA:3.40.50.970 452 826 8.5E-75 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS08635 54733a2f277a558741bd314e6b3f5da3 1240 SUPERFAMILY SSF52518 877 1095 8.54E-44 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS08635 54733a2f277a558741bd314e6b3f5da3 1240 Gene3D G3DSA:3.40.50.970 889 1099 4.0E-17 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS08635 54733a2f277a558741bd314e6b3f5da3 1240 Pfam PF16078 2-oxoglutarate dehydrogenase N-terminus 5 37 8.2E-11 T 06-07-2017 IPR032106 2-oxoglutarate dehydrogenase E1 component, N-terminal domain KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 BWK49_RS08635 54733a2f277a558741bd314e6b3f5da3 1240 PIRSF PIRSF000157 1 1240 0.0 T 06-07-2017 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 BWK49_RS08635 54733a2f277a558741bd314e6b3f5da3 1240 Pfam PF02779 Transketolase, pyrimidine binding domain 888 1088 4.9E-53 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain BWK49_RS08635 54733a2f277a558741bd314e6b3f5da3 1240 SUPERFAMILY SSF52777 100 344 1.25E-52 T 06-07-2017 BWK49_RS08635 54733a2f277a558741bd314e6b3f5da3 1240 Pfam PF16870 2-oxoglutarate dehydrogenase C-terminal 1093 1239 1.8E-40 T 06-07-2017 IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 BWK49_RS08635 54733a2f277a558741bd314e6b3f5da3 1240 Pfam PF00676 Dehydrogenase E1 component 498 825 7.5E-56 T 06-07-2017 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 BWK49_RS08635 54733a2f277a558741bd314e6b3f5da3 1240 TIGRFAM TIGR00239 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component 367 1238 5.2E-299 T 06-07-2017 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 BWK49_RS08635 54733a2f277a558741bd314e6b3f5da3 1240 SUPERFAMILY SSF52518 411 825 9.57E-82 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS25985 9d71261da8a2a7c5199ccd94a3184c25 408 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 23 407 1.7E-129 T 06-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 BWK49_RS25985 9d71261da8a2a7c5199ccd94a3184c25 408 TIGRFAM TIGR01325 O_suc_HS_sulf: O-succinylhomoserine sulfhydrylase 22 407 6.5E-197 T 06-07-2017 IPR006234 O-succinylhomoserine sulfhydrylase GO:0071268 BWK49_RS25985 9d71261da8a2a7c5199ccd94a3184c25 408 Hamap MF_02056 O-succinylhomoserine sulfhydrylase [metZ]. 23 408 51.08 T 06-07-2017 IPR006234 O-succinylhomoserine sulfhydrylase GO:0071268 BWK49_RS25985 9d71261da8a2a7c5199ccd94a3184c25 408 PIRSF PIRSF001434 19 408 3.1E-113 T 06-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 BWK49_RS25985 9d71261da8a2a7c5199ccd94a3184c25 408 Gene3D G3DSA:3.90.1150.10 273 407 1.7E-45 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 BWK49_RS25985 9d71261da8a2a7c5199ccd94a3184c25 408 SUPERFAMILY SSF53383 41 407 1.81E-104 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase BWK49_RS25985 9d71261da8a2a7c5199ccd94a3184c25 408 Gene3D G3DSA:3.40.640.10 35 269 8.7E-78 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 BWK49_RS28095 c7b2e337811c2dd855a6c5290cf10230 544 ProSitePatterns PS00455 Putative AMP-binding domain signature. 156 167 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS28095 c7b2e337811c2dd855a6c5290cf10230 544 Gene3D G3DSA:2.30.38.10 332 402 7.5E-18 T 06-07-2017 BWK49_RS28095 c7b2e337811c2dd855a6c5290cf10230 544 Gene3D G3DSA:3.40.50.980 16 161 1.3E-19 T 06-07-2017 BWK49_RS28095 c7b2e337811c2dd855a6c5290cf10230 544 Gene3D G3DSA:3.30.300.30 408 504 1.9E-18 T 06-07-2017 BWK49_RS28095 c7b2e337811c2dd855a6c5290cf10230 544 Pfam PF00501 AMP-binding enzyme 18 408 3.5E-55 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS28095 c7b2e337811c2dd855a6c5290cf10230 544 Gene3D G3DSA:3.40.50.980 162 317 3.6E-25 T 06-07-2017 BWK49_RS28095 c7b2e337811c2dd855a6c5290cf10230 544 Pfam PF13193 AMP-binding enzyme C-terminal domain 418 494 1.2E-9 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS28095 c7b2e337811c2dd855a6c5290cf10230 544 SUPERFAMILY SSF56801 15 504 4.58E-97 T 06-07-2017 BWK49_RS04960 4d8f47783a9363ca19d0036ac20f0f03 47 Gene3D G3DSA:3.40.50.720 14 42 2.3E-5 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS04960 4d8f47783a9363ca19d0036ac20f0f03 47 SUPERFAMILY SSF51735 13 43 1.18E-5 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS11875 26a2180ed0e22a3373ec48bc33b58993 407 SUPERFAMILY SSF48264 25 401 2.75E-81 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS11875 26a2180ed0e22a3373ec48bc33b58993 407 Pfam PF00067 Cytochrome P450 181 369 2.5E-24 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS11875 26a2180ed0e22a3373ec48bc33b58993 407 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 342 351 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 BWK49_RS11875 26a2180ed0e22a3373ec48bc33b58993 407 PRINTS PR00385 P450 superfamily signature 239 256 3.4E-7 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS11875 26a2180ed0e22a3373ec48bc33b58993 407 PRINTS PR00385 P450 superfamily signature 340 349 3.4E-7 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS11875 26a2180ed0e22a3373ec48bc33b58993 407 PRINTS PR00385 P450 superfamily signature 349 360 3.4E-7 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS11875 26a2180ed0e22a3373ec48bc33b58993 407 Gene3D G3DSA:1.10.630.10 11 401 1.7E-95 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS11875 26a2180ed0e22a3373ec48bc33b58993 407 PRINTS PR00359 B-class P450 signature 349 360 1.6E-29 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS11875 26a2180ed0e22a3373ec48bc33b58993 407 PRINTS PR00359 B-class P450 signature 93 104 1.6E-29 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS11875 26a2180ed0e22a3373ec48bc33b58993 407 PRINTS PR00359 B-class P450 signature 193 215 1.6E-29 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS11875 26a2180ed0e22a3373ec48bc33b58993 407 PRINTS PR00359 B-class P450 signature 156 171 1.6E-29 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS11875 26a2180ed0e22a3373ec48bc33b58993 407 PRINTS PR00359 B-class P450 signature 319 334 1.6E-29 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS11875 26a2180ed0e22a3373ec48bc33b58993 407 PRINTS PR00359 B-class P450 signature 274 285 1.6E-29 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS11875 26a2180ed0e22a3373ec48bc33b58993 407 PRINTS PR00359 B-class P450 signature 340 349 1.6E-29 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS11875 26a2180ed0e22a3373ec48bc33b58993 407 PRINTS PR00359 B-class P450 signature 291 318 1.6E-29 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS01780 50658910c36eab4528e93cface6d89d9 262 SUPERFAMILY SSF49482 37 255 2.09E-67 T 06-07-2017 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 BWK49_RS01780 50658910c36eab4528e93cface6d89d9 262 TIGRFAM TIGR02422 protocat_beta: protocatechuate 3,4-dioxygenase, beta subunit 39 256 8.5E-104 T 06-07-2017 IPR012785 Protocatechuate 3,4-dioxygenase, beta subunit GO:0005506|GO:0018578|GO:0019619|GO:0055114 KEGG: 00362+1.13.11.3|KEGG: 00624+1.13.11.3 BWK49_RS01780 50658910c36eab4528e93cface6d89d9 262 ProSitePatterns PS00083 Intradiol ring-cleavage dioxygenases signature. 100 128 - T 06-07-2017 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 BWK49_RS01780 50658910c36eab4528e93cface6d89d9 262 Pfam PF00775 Dioxygenase 83 248 1.9E-55 T 06-07-2017 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 BWK49_RS01780 50658910c36eab4528e93cface6d89d9 262 Gene3D G3DSA:2.60.130.10 61 255 3.4E-71 T 06-07-2017 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 BWK49_RS01780 50658910c36eab4528e93cface6d89d9 262 Pfam PF12391 Protocatechuate 3,4-dioxygenase beta subunit N terminal 34 64 4.4E-6 T 06-07-2017 IPR024756 Protocatechuate 3,4-dioxygenase beta subunit, N-terminal KEGG: 00362+1.13.11.3|KEGG: 00624+1.13.11.3 BWK49_RS18280 720bc6d1e31a8d0b12296a1051a20b61 269 Pfam PF01553 Acyltransferase 37 165 4.8E-16 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 BWK49_RS18280 720bc6d1e31a8d0b12296a1051a20b61 269 SUPERFAMILY SSF69593 205 259 4.05E-14 T 06-07-2017 BWK49_RS18280 720bc6d1e31a8d0b12296a1051a20b61 269 SUPERFAMILY SSF69593 22 172 4.05E-14 T 06-07-2017 BWK49_RS18280 720bc6d1e31a8d0b12296a1051a20b61 269 PIRSF PIRSF016753 1 269 4.1E-86 T 06-07-2017 IPR016676 Phospholipid/glycerol acyltransferase, predicted BWK49_RS18280 720bc6d1e31a8d0b12296a1051a20b61 269 SMART SM00563 50 169 7.8E-13 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 BWK49_RS03510 526f7cd26ef971be4dfbb141a54cb06c 354 SUPERFAMILY SSF53901 256 342 6.21E-10 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS03510 526f7cd26ef971be4dfbb141a54cb06c 354 Gene3D G3DSA:3.40.47.10 258 306 5.9E-4 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS03510 526f7cd26ef971be4dfbb141a54cb06c 354 SUPERFAMILY SSF53901 3 224 5.12E-12 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS11930 8389905759b14cf98970899ee637df7e 232 Gene3D G3DSA:3.40.50.880 32 222 2.2E-24 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like BWK49_RS11930 8389905759b14cf98970899ee637df7e 232 SUPERFAMILY SSF52317 48 200 7.02E-15 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like BWK49_RS11930 8389905759b14cf98970899ee637df7e 232 Pfam PF03575 Peptidase family S51 50 202 5.8E-11 T 06-07-2017 IPR005320 Peptidase S51 GO:0006508|GO:0008236 BWK49_RS18620 11391f18725628ac81c4326cf85a5e63 903 SUPERFAMILY SSF55681 2 248 5.47E-87 T 06-07-2017 BWK49_RS18620 11391f18725628ac81c4326cf85a5e63 903 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 669 713 3.5E-15 T 06-07-2017 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 BWK49_RS18620 11391f18725628ac81c4326cf85a5e63 903 Pfam PF01411 tRNA synthetases class II (A) 5 571 9.4E-203 T 06-07-2017 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 BWK49_RS18620 11391f18725628ac81c4326cf85a5e63 903 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 900 166.271 T 06-07-2017 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 BWK49_RS18620 11391f18725628ac81c4326cf85a5e63 903 SMART SM00863 669 713 5.9E-19 T 06-07-2017 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 BWK49_RS18620 11391f18725628ac81c4326cf85a5e63 903 Pfam PF02272 DHHA1 domain 822 893 1.5E-9 T 06-07-2017 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 BWK49_RS18620 11391f18725628ac81c4326cf85a5e63 903 PRINTS PR00980 Alanyl-tRNA synthetase signature 304 317 5.7E-27 T 06-07-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 BWK49_RS18620 11391f18725628ac81c4326cf85a5e63 903 PRINTS PR00980 Alanyl-tRNA synthetase signature 196 207 5.7E-27 T 06-07-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 BWK49_RS18620 11391f18725628ac81c4326cf85a5e63 903 PRINTS PR00980 Alanyl-tRNA synthetase signature 69 80 5.7E-27 T 06-07-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 BWK49_RS18620 11391f18725628ac81c4326cf85a5e63 903 PRINTS PR00980 Alanyl-tRNA synthetase signature 280 296 5.7E-27 T 06-07-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 BWK49_RS18620 11391f18725628ac81c4326cf85a5e63 903 PRINTS PR00980 Alanyl-tRNA synthetase signature 229 242 5.7E-27 T 06-07-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 BWK49_RS18620 11391f18725628ac81c4326cf85a5e63 903 Gene3D G3DSA:3.30.930.10 2 245 4.0E-92 T 06-07-2017 BWK49_RS18620 11391f18725628ac81c4326cf85a5e63 903 SUPERFAMILY SSF55186 573 718 1.44E-40 T 06-07-2017 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 BWK49_RS18620 11391f18725628ac81c4326cf85a5e63 903 SUPERFAMILY SSF50447 461 568 2.82E-15 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain BWK49_RS18620 11391f18725628ac81c4326cf85a5e63 903 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 5 879 8.6E-244 T 06-07-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 BWK49_RS18620 11391f18725628ac81c4326cf85a5e63 903 SUPERFAMILY SSF101353 249 443 3.27E-54 T 06-07-2017 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 BWK49_RS17680 5a75d29b00c28a78a94f756cd2f1b90e 352 Pfam PF13489 Methyltransferase domain 92 207 1.1E-11 T 06-07-2017 BWK49_RS17680 5a75d29b00c28a78a94f756cd2f1b90e 352 SUPERFAMILY SSF53335 77 210 9.32E-19 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS17680 5a75d29b00c28a78a94f756cd2f1b90e 352 Gene3D G3DSA:3.40.50.150 75 226 1.5E-16 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS08815 a62cae59578b718cdd97a19f2fd9f45a 161 Pfam PF02082 Transcriptional regulator 2 83 3.1E-24 T 06-07-2017 IPR000944 Transcription regulator Rrf2-type BWK49_RS08815 a62cae59578b718cdd97a19f2fd9f45a 161 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 49 67 - T 06-07-2017 IPR030489 Transcription regulator Rrf2-type, conserved site BWK49_RS08815 a62cae59578b718cdd97a19f2fd9f45a 161 Gene3D G3DSA:1.10.10.10 2 133 7.4E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS08815 a62cae59578b718cdd97a19f2fd9f45a 161 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 2 131 3.3E-39 T 06-07-2017 IPR000944 Transcription regulator Rrf2-type BWK49_RS08815 a62cae59578b718cdd97a19f2fd9f45a 161 SUPERFAMILY SSF46785 2 132 8.33E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS18435 22c8ccd19ddd459c0d23179b94875d85 403 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 253 392 1.5E-66 T 06-07-2017 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 BWK49_RS18435 22c8ccd19ddd459c0d23179b94875d85 403 Gene3D G3DSA:3.30.300.10 13 150 8.4E-43 T 06-07-2017 BWK49_RS18435 22c8ccd19ddd459c0d23179b94875d85 403 SUPERFAMILY SSF55973 253 401 2.94E-67 T 06-07-2017 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 BWK49_RS18435 22c8ccd19ddd459c0d23179b94875d85 403 Pfam PF02772 S-adenosylmethionine synthetase, central domain 130 251 3.2E-44 T 06-07-2017 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 BWK49_RS18435 22c8ccd19ddd459c0d23179b94875d85 403 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 7 106 1.4E-37 T 06-07-2017 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 BWK49_RS18435 22c8ccd19ddd459c0d23179b94875d85 403 SUPERFAMILY SSF55973 126 252 2.63E-45 T 06-07-2017 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 BWK49_RS18435 22c8ccd19ddd459c0d23179b94875d85 403 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 4 403 56.867 T 06-07-2017 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 BWK49_RS18435 22c8ccd19ddd459c0d23179b94875d85 403 Gene3D G3DSA:3.30.300.10 264 402 1.1E-67 T 06-07-2017 BWK49_RS18435 22c8ccd19ddd459c0d23179b94875d85 403 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 7 403 3.9E-164 T 06-07-2017 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 BWK49_RS18435 22c8ccd19ddd459c0d23179b94875d85 403 SUPERFAMILY SSF55973 6 114 1.41E-41 T 06-07-2017 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 BWK49_RS18435 22c8ccd19ddd459c0d23179b94875d85 403 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 279 287 - T 06-07-2017 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 BWK49_RS18435 22c8ccd19ddd459c0d23179b94875d85 403 Gene3D G3DSA:3.30.300.10 151 253 6.5E-39 T 06-07-2017 BWK49_RS18435 22c8ccd19ddd459c0d23179b94875d85 403 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 131 141 - T 06-07-2017 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 BWK49_RS18435 22c8ccd19ddd459c0d23179b94875d85 403 PIRSF PIRSF000497 1 403 5.6E-161 T 06-07-2017 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 BWK49_RS04325 b46c5986bda8423b9e1b6d5432f97762 99 Pfam PF10904 Protein of unknown function (DUF2694) 14 90 1.8E-5 T 06-07-2017 IPR024426 Protein of unknown function DUF2694 BWK49_RS11415 19dbfc9196b850d419b8e97557bbda9c 198 Pfam PF02627 Carboxymuconolactone decarboxylase family 49 122 5.9E-7 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 BWK49_RS11415 19dbfc9196b850d419b8e97557bbda9c 198 Gene3D G3DSA:1.20.1290.10 40 181 2.4E-35 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 BWK49_RS11415 19dbfc9196b850d419b8e97557bbda9c 198 SUPERFAMILY SSF69118 38 179 5.45E-35 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 BWK49_RS28570 e3409a420a9284683dca0eae19bb7f4c 136 Pfam PF13470 PIN domain 6 113 1.7E-15 T 06-07-2017 IPR002716 PIN domain BWK49_RS28570 e3409a420a9284683dca0eae19bb7f4c 136 SUPERFAMILY SSF88723 6 119 5.1E-10 T 06-07-2017 IPR029060 PIN domain-like BWK49_RS28570 e3409a420a9284683dca0eae19bb7f4c 136 TIGRFAM TIGR00305 TIGR00305: putative toxin-antitoxin system toxin component, PIN family 6 119 6.3E-17 T 06-07-2017 IPR002850 PIN family, putative toxin-antitoxin system toxin component BWK49_RS22245 0e7a9da3d5112be19e11137f537e08b6 186 Pfam PF01814 Hemerythrin HHE cation binding domain 12 127 2.5E-10 T 06-07-2017 IPR012312 Haemerythrin-like Reactome: R-HSA-390471 BWK49_RS22245 0e7a9da3d5112be19e11137f537e08b6 186 Gene3D G3DSA:1.20.120.520 32 144 5.4E-4 T 06-07-2017 BWK49_RS06650 082faff3c13b8f382bc55dccd7cfa8f4 143 Gene3D G3DSA:1.10.10.10 2 136 1.2E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS06650 082faff3c13b8f382bc55dccd7cfa8f4 143 SMART SM00347 25 125 4.8E-25 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 BWK49_RS06650 082faff3c13b8f382bc55dccd7cfa8f4 143 Pfam PF01047 MarR family 33 90 6.4E-14 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 BWK49_RS06650 082faff3c13b8f382bc55dccd7cfa8f4 143 ProSitePatterns PS01117 MarR-type HTH domain signature. 64 98 - T 06-07-2017 IPR023187 Transcriptional regulator MarR-type, conserved site BWK49_RS06650 082faff3c13b8f382bc55dccd7cfa8f4 143 SUPERFAMILY SSF46785 4 140 4.69E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS04420 5e58d3ec6ba52993295ff792e0c3cdea 536 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 280 474 1.2E-7 T 06-07-2017 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain BWK49_RS04420 5e58d3ec6ba52993295ff792e0c3cdea 536 Gene3D G3DSA:3.40.50.300 278 512 6.0E-23 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS04420 5e58d3ec6ba52993295ff792e0c3cdea 536 SUPERFAMILY SSF52540 278 507 2.33E-19 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS12555 2f6da2b71b7d342c4cbfebf5d587345c 134 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 10 123 2.6E-7 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain BWK49_RS12555 2f6da2b71b7d342c4cbfebf5d587345c 134 SUPERFAMILY SSF54593 8 124 6.05E-21 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS12555 2f6da2b71b7d342c4cbfebf5d587345c 134 Gene3D G3DSA:3.10.180.10 8 125 6.6E-27 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS27470 6c121c7558ab9db8d5b2a03087b25088 525 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 101 281 2.8E-23 T 06-07-2017 IPR004474 Cell envelope-related transcriptional attenuator domain BWK49_RS27470 6c121c7558ab9db8d5b2a03087b25088 525 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 390 470 4.6E-12 T 06-07-2017 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain BWK49_RS27470 6c121c7558ab9db8d5b2a03087b25088 525 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 101 281 2.8E-30 T 06-07-2017 IPR004474 Cell envelope-related transcriptional attenuator domain BWK49_RS07550 9e754f7088eda8b410aefb3ddfe314f5 289 Hamap MF_00276 Potassium-transporting ATPase KdpC subunit [kdpC]. 5 284 28.05 T 06-07-2017 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 BWK49_RS07550 9e754f7088eda8b410aefb3ddfe314f5 289 Pfam PF02669 K+-transporting ATPase, c chain 9 101 1.5E-25 T 06-07-2017 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 BWK49_RS07550 9e754f7088eda8b410aefb3ddfe314f5 289 Pfam PF02669 K+-transporting ATPase, c chain 210 282 2.4E-28 T 06-07-2017 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 BWK49_RS25790 4a75d05a92612fc3944074f4f5b254a4 291 Pfam PF00296 Luciferase-like monooxygenase 22 246 2.2E-40 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS25790 4a75d05a92612fc3944074f4f5b254a4 291 Gene3D G3DSA:3.20.20.30 17 289 4.0E-64 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS25790 4a75d05a92612fc3944074f4f5b254a4 291 TIGRFAM TIGR03560 F420_Rv1855c: probable F420-dependent oxidoreductase, Rv1855c family 13 230 2.1E-93 T 06-07-2017 IPR019952 F420-dependent oxidoreductase-predicted, Rv1855c BWK49_RS25790 4a75d05a92612fc3944074f4f5b254a4 291 SUPERFAMILY SSF51679 7 289 7.91E-61 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS13500 fbf77779335277710651c43d7e7f9f36 242 Pfam PF02571 Precorrin-6x reductase CbiJ/CobK 2 237 2.2E-68 T 06-07-2017 IPR003723 Precorrin-6x reductase GO:0009236|GO:0016994|GO:0055114 BWK49_RS13500 fbf77779335277710651c43d7e7f9f36 242 TIGRFAM TIGR00715 precor6x_red: precorrin-6x reductase 1 238 7.6E-72 T 06-07-2017 IPR003723 Precorrin-6x reductase GO:0009236|GO:0016994|GO:0055114 BWK49_RS24710 668c6ed532396d1bdfea0addbfe09b8a 461 ProDom PD008243 RV1792C/MT1741/MB1728C RV1945/MT1995 MB1980 MB0098C RV3466/MT3572 VERY RV1128C/MT1160 RV1148C/MT1183 MB1159C RV0095C 8 92 2.0E-19 T 06-07-2017 BWK49_RS24710 668c6ed532396d1bdfea0addbfe09b8a 461 SMART SM00507 352 404 5.8E-4 T 06-07-2017 IPR003615 HNH nuclease BWK49_RS24710 668c6ed532396d1bdfea0addbfe09b8a 461 Pfam PF02720 Domain of unknown function (DUF222) 38 361 2.1E-92 T 06-07-2017 IPR003870 Domain of unknown function DUF222 BWK49_RS14565 b14c2974d338a214865d73ca9b4c6ef9 237 Gene3D G3DSA:3.60.15.10 4 233 1.2E-46 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS14565 b14c2974d338a214865d73ca9b4c6ef9 237 SUPERFAMILY SSF56281 3 233 4.48E-40 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS14565 b14c2974d338a214865d73ca9b4c6ef9 237 Pfam PF00753 Metallo-beta-lactamase superfamily 19 214 6.2E-19 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS14565 b14c2974d338a214865d73ca9b4c6ef9 237 SMART SM00849 21 214 4.0E-21 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS10140 b6122b0995ceda26d90ea42e602b386e 371 SUPERFAMILY SSF47203 231 362 7.09E-33 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS10140 b6122b0995ceda26d90ea42e602b386e 371 Gene3D G3DSA:2.40.110.10 117 199 6.5E-10 T 06-07-2017 BWK49_RS10140 b6122b0995ceda26d90ea42e602b386e 371 Gene3D G3DSA:1.10.540.10 1 112 1.2E-10 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS10140 b6122b0995ceda26d90ea42e602b386e 371 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 231 360 4.1E-22 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS10140 b6122b0995ceda26d90ea42e602b386e 371 Gene3D G3DSA:1.20.140.10 231 362 9.1E-30 T 06-07-2017 BWK49_RS10140 b6122b0995ceda26d90ea42e602b386e 371 SUPERFAMILY SSF56645 1 199 6.41E-33 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS10140 b6122b0995ceda26d90ea42e602b386e 371 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 112 4.6E-8 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS28140 87e86880a430cb987717c2303d0605c7 402 Gene3D G3DSA:3.40.47.10 37 116 1.4E-5 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS28140 87e86880a430cb987717c2303d0605c7 402 Gene3D G3DSA:3.40.47.10 210 241 1.4E-5 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS28140 87e86880a430cb987717c2303d0605c7 402 PIRSF PIRSF000429 3 394 1.6E-15 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 BWK49_RS28140 87e86880a430cb987717c2303d0605c7 402 SUPERFAMILY SSF53901 4 122 7.88E-14 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS28140 87e86880a430cb987717c2303d0605c7 402 SUPERFAMILY SSF53901 218 245 7.88E-14 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS28140 87e86880a430cb987717c2303d0605c7 402 SUPERFAMILY SSF53901 251 391 5.76E-19 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS28140 87e86880a430cb987717c2303d0605c7 402 Gene3D G3DSA:3.40.47.10 260 383 1.1E-7 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS28140 87e86880a430cb987717c2303d0605c7 402 Gene3D G3DSA:3.40.47.10 160 199 1.1E-7 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS20515 753038235b55e166709733e60b344616 155 SUPERFAMILY SSF55811 6 149 5.28E-36 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 BWK49_RS20515 753038235b55e166709733e60b344616 155 Pfam PF00293 NUDIX domain 19 138 1.2E-19 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 BWK49_RS20515 753038235b55e166709733e60b344616 155 ProSitePatterns PS00893 Nudix box signature. 48 69 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 BWK49_RS20515 753038235b55e166709733e60b344616 155 PRINTS PR00502 NUDIX hydrolase family signature 43 57 3.3E-6 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 BWK49_RS20515 753038235b55e166709733e60b344616 155 PRINTS PR00502 NUDIX hydrolase family signature 57 72 3.3E-6 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 BWK49_RS20515 753038235b55e166709733e60b344616 155 Gene3D G3DSA:3.90.79.10 4 147 1.1E-35 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 BWK49_RS04945 e3fca44cd5ad007e073ade9a8bb41737 514 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 9 293 4.7E-77 T 06-07-2017 IPR005693 Virulence factor Mce protein BWK49_RS04945 e3fca44cd5ad007e073ade9a8bb41737 514 Pfam PF02470 MlaD protein 39 112 4.1E-15 T 06-07-2017 IPR003399 Mce/MlaD BWK49_RS04945 e3fca44cd5ad007e073ade9a8bb41737 514 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 149 282 1.6E-7 T 06-07-2017 IPR024516 Mammalian cell entry, C-terminal BWK49_RS05200 1dfc31fe30a4e748ee7ed6f099b6a968 225 SUPERFAMILY SSF46689 5 85 1.13E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS05200 1dfc31fe30a4e748ee7ed6f099b6a968 225 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 60 2.1E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS05200 1dfc31fe30a4e748ee7ed6f099b6a968 225 SUPERFAMILY SSF48498 88 185 9.39E-6 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS05200 1dfc31fe30a4e748ee7ed6f099b6a968 225 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 3.5E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS05200 1dfc31fe30a4e748ee7ed6f099b6a968 225 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 3.5E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS05200 1dfc31fe30a4e748ee7ed6f099b6a968 225 Gene3D G3DSA:1.10.357.10 5 185 9.6E-29 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS07310 54106c7dfc8ad08603c77d90ce9757e2 565 Gene3D G3DSA:3.50.50.60 13 127 1.8E-50 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS07310 54106c7dfc8ad08603c77d90ce9757e2 565 Gene3D G3DSA:3.50.50.60 473 554 1.8E-50 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS07310 54106c7dfc8ad08603c77d90ce9757e2 565 Gene3D G3DSA:3.50.50.60 166 266 1.8E-50 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS07310 54106c7dfc8ad08603c77d90ce9757e2 565 Pfam PF05199 GMC oxidoreductase 418 547 1.0E-24 T 06-07-2017 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 BWK49_RS07310 54106c7dfc8ad08603c77d90ce9757e2 565 Pfam PF01494 FAD binding domain 15 46 1.6E-6 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 BWK49_RS07310 54106c7dfc8ad08603c77d90ce9757e2 565 SUPERFAMILY SSF51905 12 264 7.26E-45 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS07310 54106c7dfc8ad08603c77d90ce9757e2 565 SUPERFAMILY SSF51905 493 554 7.26E-45 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS07310 54106c7dfc8ad08603c77d90ce9757e2 565 SUPERFAMILY SSF51905 292 300 7.26E-45 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS01350 28046496294ff9e1ee6262bc11045e16 401 Gene3D G3DSA:1.10.150.130 77 181 1.5E-8 T 06-07-2017 IPR023109 Integrase/recombinase, N-terminal BWK49_RS01350 28046496294ff9e1ee6262bc11045e16 401 Pfam PF00589 Phage integrase family 194 376 1.3E-21 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 BWK49_RS01350 28046496294ff9e1ee6262bc11045e16 401 Pfam PF14657 AP2-like DNA-binding integrase domain 31 69 5.1E-6 T 06-07-2017 IPR028259 AP2-like integrase, N-terminal domain BWK49_RS01350 28046496294ff9e1ee6262bc11045e16 401 SUPERFAMILY SSF56349 76 380 1.82E-52 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 BWK49_RS01350 28046496294ff9e1ee6262bc11045e16 401 Gene3D G3DSA:1.10.443.10 193 382 1.9E-36 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 BWK49_RS07235 745a0b8999c8b605fb8b7230b89b3cc8 205 Pfam PF13532 2OG-Fe(II) oxygenase superfamily 79 199 1.0E-12 T 06-07-2017 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like BWK49_RS07235 745a0b8999c8b605fb8b7230b89b3cc8 205 SUPERFAMILY SSF51197 36 200 7.28E-43 T 06-07-2017 BWK49_RS07235 745a0b8999c8b605fb8b7230b89b3cc8 205 Gene3D G3DSA:2.60.120.590 82 200 3.7E-17 T 06-07-2017 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like BWK49_RS12905 0d57e1568f5fbe42f87ae720b3cd5fb5 203 SUPERFAMILY SSF81452 12 201 3.27E-56 T 06-07-2017 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 BWK49_RS12905 0d57e1568f5fbe42f87ae720b3cd5fb5 203 Pfam PF00510 Cytochrome c oxidase subunit III 22 201 2.8E-26 T 06-07-2017 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 BWK49_RS12905 0d57e1568f5fbe42f87ae720b3cd5fb5 203 Gene3D G3DSA:1.20.120.80 23 202 3.0E-54 T 06-07-2017 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 BWK49_RS24080 f582f190694767d6d55b24954d297b88 311 Pfam PF00149 Calcineurin-like phosphoesterase 54 245 3.8E-12 T 06-07-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 BWK49_RS24080 f582f190694767d6d55b24954d297b88 311 SUPERFAMILY SSF56300 54 269 3.8E-41 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like BWK49_RS24080 f582f190694767d6d55b24954d297b88 311 Gene3D G3DSA:3.60.21.10 52 275 2.0E-30 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like BWK49_RS07470 9da3519f8ff30b00e8fcf2d5285b7284 326 Gene3D G3DSA:3.40.50.2020 168 295 4.4E-44 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like BWK49_RS07470 9da3519f8ff30b00e8fcf2d5285b7284 326 Pfam PF14572 Phosphoribosyl synthetase-associated domain 216 322 3.6E-20 T 06-07-2017 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 BWK49_RS07470 9da3519f8ff30b00e8fcf2d5285b7284 326 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 136 151 - T 06-07-2017 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 BWK49_RS07470 9da3519f8ff30b00e8fcf2d5285b7284 326 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 12 128 1.0E-45 T 06-07-2017 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 BWK49_RS07470 9da3519f8ff30b00e8fcf2d5285b7284 326 SUPERFAMILY SSF53271 77 314 4.16E-60 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like BWK49_RS07470 9da3519f8ff30b00e8fcf2d5285b7284 326 SMART SM01400 12 128 1.3E-71 T 06-07-2017 BWK49_RS07470 9da3519f8ff30b00e8fcf2d5285b7284 326 Gene3D G3DSA:3.40.50.2020 9 167 1.4E-71 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like BWK49_RS07470 9da3519f8ff30b00e8fcf2d5285b7284 326 Hamap MF_00583_B Ribose-phosphate pyrophosphokinase [prs]. 12 323 45.271 T 06-07-2017 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 BWK49_RS07470 9da3519f8ff30b00e8fcf2d5285b7284 326 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 13 323 2.4E-120 T 06-07-2017 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 BWK49_RS02920 d3adb3d6b851625061822c6d1a3c2dda 777 SUPERFAMILY SSF52540 69 238 4.72E-39 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS02920 d3adb3d6b851625061822c6d1a3c2dda 777 SUPERFAMILY SSF52540 270 417 4.72E-39 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS02920 d3adb3d6b851625061822c6d1a3c2dda 777 Gene3D G3DSA:3.40.50.300 44 238 2.3E-27 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS02920 d3adb3d6b851625061822c6d1a3c2dda 777 Gene3D G3DSA:3.40.50.300 296 446 4.5E-20 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS02920 d3adb3d6b851625061822c6d1a3c2dda 777 SMART SM00490 328 406 4.2E-14 T 06-07-2017 IPR001650 Helicase, C-terminal BWK49_RS02920 d3adb3d6b851625061822c6d1a3c2dda 777 Pfam PF00270 DEAD/DEAH box helicase 62 236 1.1E-19 T 06-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 BWK49_RS02920 d3adb3d6b851625061822c6d1a3c2dda 777 Pfam PF00271 Helicase conserved C-terminal domain 299 406 3.6E-10 T 06-07-2017 IPR001650 Helicase, C-terminal BWK49_RS02920 d3adb3d6b851625061822c6d1a3c2dda 777 TIGRFAM TIGR03817 DECH_helic: helicase/secretion neighborhood putative DEAH-box helicase 23 771 0.0 T 06-07-2017 IPR022307 DEAD/DEAH-box helicase, putative, actinobacteria BWK49_RS02920 d3adb3d6b851625061822c6d1a3c2dda 777 Pfam PF09369 Domain of unknown function (DUF1998) 664 744 5.3E-18 T 06-07-2017 IPR018973 DEAD/DEAH-box helicase, putative BWK49_RS02920 d3adb3d6b851625061822c6d1a3c2dda 777 SMART SM00487 55 266 1.5E-21 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain BWK49_RS19060 8bef767b8371b04f3e5f18e8e7386a65 205 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 63 7.6E-17 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS19060 8bef767b8371b04f3e5f18e8e7386a65 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 9.6E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS19060 8bef767b8371b04f3e5f18e8e7386a65 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 9.6E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS19060 8bef767b8371b04f3e5f18e8e7386a65 205 SUPERFAMILY SSF46689 9 75 5.99E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS19060 8bef767b8371b04f3e5f18e8e7386a65 205 Gene3D G3DSA:1.10.357.10 14 190 1.3E-29 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS19060 8bef767b8371b04f3e5f18e8e7386a65 205 SUPERFAMILY SSF48498 86 188 7.12E-10 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS15555 00d8ef3f67376100a875465f4d86729e 278 SUPERFAMILY SSF51735 7 276 6.4E-65 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS15555 00d8ef3f67376100a875465f4d86729e 278 Gene3D G3DSA:3.40.50.720 1 275 8.3E-69 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS15555 00d8ef3f67376100a875465f4d86729e 278 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 274 1.7E-47 T 06-07-2017 BWK49_RS15555 00d8ef3f67376100a875465f4d86729e 278 TIGRFAM TIGR03971 SDR_subfam_1: SDR family mycofactocin-dependent oxidoreductase 5 277 6.4E-120 T 06-07-2017 IPR023985 Mycofactocin-dependent oxidoreductase BWK49_RS15555 00d8ef3f67376100a875465f4d86729e 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 5.4E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15555 00d8ef3f67376100a875465f4d86729e 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 160 5.4E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15555 00d8ef3f67376100a875465f4d86729e 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 189 5.4E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15555 00d8ef3f67376100a875465f4d86729e 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 191 208 5.4E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15555 00d8ef3f67376100a875465f4d86729e 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 239 259 5.4E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15555 00d8ef3f67376100a875465f4d86729e 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 95 106 5.4E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15555 00d8ef3f67376100a875465f4d86729e 278 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 158 2.8E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15555 00d8ef3f67376100a875465f4d86729e 278 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 170 189 2.8E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15555 00d8ef3f67376100a875465f4d86729e 278 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 95 106 2.8E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS09100 90f81b60933cd41e765d73220f86a860 435 TIGRFAM TIGR01513 NAPRTase_put: nicotinate phosphoribosyltransferase 8 423 3.7E-136 T 06-07-2017 IPR006405 Nicotinate phosphoribosyltransferase pncB-type GO:0004516|GO:0019358 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 BWK49_RS09100 90f81b60933cd41e765d73220f86a860 435 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 153 346 9.4E-6 T 06-07-2017 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 BWK49_RS09100 90f81b60933cd41e765d73220f86a860 435 Gene3D G3DSA:3.20.140.10 3 369 1.6E-88 T 06-07-2017 BWK49_RS09100 90f81b60933cd41e765d73220f86a860 435 SUPERFAMILY SSF54675 3 134 3.7E-37 T 06-07-2017 BWK49_RS09100 90f81b60933cd41e765d73220f86a860 435 PIRSF PIRSF000484 1 429 4.0E-102 T 06-07-2017 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 BWK49_RS09100 90f81b60933cd41e765d73220f86a860 435 SUPERFAMILY SSF51690 136 428 4.97E-81 T 06-07-2017 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 BWK49_RS02530 26b41e1830882180d627d42f341dcc97 352 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 146 335 6.0E-49 T 06-07-2017 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 BWK49_RS02530 26b41e1830882180d627d42f341dcc97 352 SUPERFAMILY SSF51735 2 163 8.44E-41 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS02530 26b41e1830882180d627d42f341dcc97 352 PIRSF PIRSF000148 1 352 1.4E-105 T 06-07-2017 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 BWK49_RS02530 26b41e1830882180d627d42f341dcc97 352 SUPERFAMILY SSF55347 136 336 3.14E-59 T 06-07-2017 BWK49_RS02530 26b41e1830882180d627d42f341dcc97 352 SMART SM00859 3 124 1.2E-29 T 06-07-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 BWK49_RS02530 26b41e1830882180d627d42f341dcc97 352 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 4 116 4.7E-25 T 06-07-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 BWK49_RS02530 26b41e1830882180d627d42f341dcc97 352 Gene3D G3DSA:3.30.360.10 150 331 6.3E-69 T 06-07-2017 BWK49_RS02530 26b41e1830882180d627d42f341dcc97 352 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 4 350 1.1E-139 T 06-07-2017 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 BWK49_RS02530 26b41e1830882180d627d42f341dcc97 352 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 1 349 34.32 T 06-07-2017 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 BWK49_RS02530 26b41e1830882180d627d42f341dcc97 352 ProSitePatterns PS01103 Aspartate-semialdehyde dehydrogenase signature. 250 264 - T 06-07-2017 IPR000319 Aspartate-semialdehyde dehydrogenase, conserved site GO:0004073|GO:0006520|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 BWK49_RS02530 26b41e1830882180d627d42f341dcc97 352 Gene3D G3DSA:3.40.50.720 2 149 1.0E-53 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS12430 a9cd4a52dc961bcaa8c9bc12e069beb8 512 Gene3D G3DSA:3.50.50.60 27 295 7.5E-36 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS12430 a9cd4a52dc961bcaa8c9bc12e069beb8 512 SUPERFAMILY SSF51905 27 353 4.14E-31 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS12430 a9cd4a52dc961bcaa8c9bc12e069beb8 512 ProSitePatterns PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1. 31 48 - T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 BWK49_RS12430 a9cd4a52dc961bcaa8c9bc12e069beb8 512 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 55 67 1.0E-28 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 BWK49_RS12430 a9cd4a52dc961bcaa8c9bc12e069beb8 512 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 101 113 1.0E-28 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 BWK49_RS12430 a9cd4a52dc961bcaa8c9bc12e069beb8 512 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 39 49 1.0E-28 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 BWK49_RS12430 a9cd4a52dc961bcaa8c9bc12e069beb8 512 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 373 385 1.0E-28 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 BWK49_RS12430 a9cd4a52dc961bcaa8c9bc12e069beb8 512 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 26 38 1.0E-28 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 BWK49_RS12430 a9cd4a52dc961bcaa8c9bc12e069beb8 512 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 343 349 1.0E-28 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 BWK49_RS12430 a9cd4a52dc961bcaa8c9bc12e069beb8 512 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 406 501 1.6E-13 T 06-07-2017 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 BWK49_RS12430 a9cd4a52dc961bcaa8c9bc12e069beb8 512 Pfam PF01266 FAD dependent oxidoreductase 27 381 8.2E-46 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 BWK49_RS12430 a9cd4a52dc961bcaa8c9bc12e069beb8 512 ProSitePatterns PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2. 378 388 - T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 BWK49_RS15835 73503504fce5552b6f5b65e428ac11a6 159 SUPERFAMILY SSF54427 3 146 3.93E-22 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS15835 73503504fce5552b6f5b65e428ac11a6 159 Gene3D G3DSA:3.10.450.50 9 138 7.0E-11 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS15835 73503504fce5552b6f5b65e428ac11a6 159 Pfam PF13577 SnoaL-like domain 10 105 1.5E-7 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain BWK49_RS19705 ac819913926e97ec0af59f51ad10157b 399 Gene3D G3DSA:1.10.540.10 11 110 8.8E-18 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS19705 ac819913926e97ec0af59f51ad10157b 399 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 113 208 4.3E-19 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 BWK49_RS19705 ac819913926e97ec0af59f51ad10157b 399 Gene3D G3DSA:1.20.140.10 212 389 2.0E-28 T 06-07-2017 BWK49_RS19705 ac819913926e97ec0af59f51ad10157b 399 Gene3D G3DSA:2.40.110.10 113 211 3.6E-32 T 06-07-2017 BWK49_RS19705 ac819913926e97ec0af59f51ad10157b 399 SUPERFAMILY SSF47203 222 382 5.48E-16 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS19705 ac819913926e97ec0af59f51ad10157b 399 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 16 109 9.1E-11 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS19705 ac819913926e97ec0af59f51ad10157b 399 SUPERFAMILY SSF56645 10 235 1.83E-62 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS19705 ac819913926e97ec0af59f51ad10157b 399 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 222 380 3.1E-18 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS22350 c3f237fc026a1cd09b4906cb8abe662a 301 Pfam PF00561 alpha/beta hydrolase fold 22 126 2.3E-18 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS22350 c3f237fc026a1cd09b4906cb8abe662a 301 Gene3D G3DSA:3.40.50.1820 2 285 2.5E-51 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS22350 c3f237fc026a1cd09b4906cb8abe662a 301 SUPERFAMILY SSF53474 5 286 7.8E-44 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS10890 f8b528c8eaa28556b38ef5116e0bc293 249 Gene3D G3DSA:3.40.50.720 5 248 6.3E-64 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS10890 f8b528c8eaa28556b38ef5116e0bc293 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 2.9E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS10890 f8b528c8eaa28556b38ef5116e0bc293 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 2.9E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS10890 f8b528c8eaa28556b38ef5116e0bc293 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 2.9E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS10890 f8b528c8eaa28556b38ef5116e0bc293 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 2.2E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS10890 f8b528c8eaa28556b38ef5116e0bc293 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 2.2E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS10890 f8b528c8eaa28556b38ef5116e0bc293 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 2.2E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS10890 f8b528c8eaa28556b38ef5116e0bc293 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 2.2E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS10890 f8b528c8eaa28556b38ef5116e0bc293 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 2.2E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS10890 f8b528c8eaa28556b38ef5116e0bc293 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 2.2E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS10890 f8b528c8eaa28556b38ef5116e0bc293 249 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS10890 f8b528c8eaa28556b38ef5116e0bc293 249 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 19 246 9.6E-46 T 06-07-2017 BWK49_RS10890 f8b528c8eaa28556b38ef5116e0bc293 249 SUPERFAMILY SSF51735 5 248 8.21E-63 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS17470 e9e22d4cd0031040683aa687615ddb9f 201 Pfam PF03167 Uracil DNA glycosylase superfamily 22 180 5.7E-23 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 BWK49_RS17470 e9e22d4cd0031040683aa687615ddb9f 201 SMART SM00987 20 181 4.3E-6 T 06-07-2017 BWK49_RS17470 e9e22d4cd0031040683aa687615ddb9f 201 SMART SM00986 20 181 4.3E-6 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 BWK49_RS17470 e9e22d4cd0031040683aa687615ddb9f 201 SUPERFAMILY SSF52141 18 183 7.85E-36 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 BWK49_RS17470 e9e22d4cd0031040683aa687615ddb9f 201 Gene3D G3DSA:3.40.470.10 19 185 8.7E-47 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 BWK49_RS19495 be75dcc0e80c08fb7668d7d4ed7a160e 228 Gene3D G3DSA:3.10.310.10 123 217 1.9E-13 T 06-07-2017 BWK49_RS19495 be75dcc0e80c08fb7668d7d4ed7a160e 228 Gene3D G3DSA:3.10.310.10 3 122 3.4E-25 T 06-07-2017 BWK49_RS19495 be75dcc0e80c08fb7668d7d4ed7a160e 228 Pfam PF02567 Phenazine biosynthesis-like protein 143 197 3.7E-6 T 06-07-2017 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 BWK49_RS19495 be75dcc0e80c08fb7668d7d4ed7a160e 228 Pfam PF02567 Phenazine biosynthesis-like protein 10 132 1.9E-17 T 06-07-2017 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 BWK49_RS19495 be75dcc0e80c08fb7668d7d4ed7a160e 228 SUPERFAMILY SSF54506 1 220 1.47E-35 T 06-07-2017 BWK49_RS06580 6428e2a70bd5685a5de43f70030b7dff 141 Pfam PF02391 MoaE protein 10 121 1.1E-30 T 06-07-2017 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 BWK49_RS06580 6428e2a70bd5685a5de43f70030b7dff 141 Gene3D G3DSA:3.90.1170.40 4 139 5.6E-39 T 06-07-2017 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 BWK49_RS06580 6428e2a70bd5685a5de43f70030b7dff 141 SUPERFAMILY SSF54690 10 139 2.22E-36 T 06-07-2017 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 BWK49_RS13865 9be2a5c9711badc9165bdb790d6d0c4e 172 Pfam PF13577 SnoaL-like domain 14 135 8.5E-28 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain BWK49_RS13865 9be2a5c9711badc9165bdb790d6d0c4e 172 Gene3D G3DSA:3.10.450.50 17 143 1.6E-28 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS13865 9be2a5c9711badc9165bdb790d6d0c4e 172 SUPERFAMILY SSF54427 13 153 2.29E-34 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS26930 5ecf5bc0976a973a6d96f759b1c22b27 409 Pfam PF03741 Integral membrane protein TerC family 69 273 5.9E-48 T 06-07-2017 IPR005496 Integral membrane protein TerC GO:0016021 BWK49_RS26930 5ecf5bc0976a973a6d96f759b1c22b27 409 TIGRFAM TIGR03718 R_switched_Alx: integral membrane protein, TerC family 5 317 3.3E-107 T 06-07-2017 IPR022369 Integral membrane protein TerC, riboswitch-linked GO:0016021 BWK49_RS16840 40709181e30bb44ce905bb1ce80bb7b1 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 1.4E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS16840 40709181e30bb44ce905bb1ce80bb7b1 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 1.4E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS16840 40709181e30bb44ce905bb1ce80bb7b1 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 1.4E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS16840 40709181e30bb44ce905bb1ce80bb7b1 248 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 245 3.3E-59 T 06-07-2017 BWK49_RS16840 40709181e30bb44ce905bb1ce80bb7b1 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 1.1E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS16840 40709181e30bb44ce905bb1ce80bb7b1 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 1.1E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS16840 40709181e30bb44ce905bb1ce80bb7b1 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 1.1E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS16840 40709181e30bb44ce905bb1ce80bb7b1 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.1E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS16840 40709181e30bb44ce905bb1ce80bb7b1 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 1.1E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS16840 40709181e30bb44ce905bb1ce80bb7b1 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 1.1E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS16840 40709181e30bb44ce905bb1ce80bb7b1 248 SUPERFAMILY SSF51735 9 247 6.42E-79 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS16840 40709181e30bb44ce905bb1ce80bb7b1 248 Gene3D G3DSA:3.40.50.720 4 247 1.2E-83 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS16840 40709181e30bb44ce905bb1ce80bb7b1 248 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 187 1.3E-4 T 06-07-2017 BWK49_RS15595 4014d242aa04e35bee76d0203eec73a9 273 Pfam PF04072 Leucine carboxyl methyltransferase 25 181 2.1E-20 T 06-07-2017 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 BWK49_RS15595 4014d242aa04e35bee76d0203eec73a9 273 PIRSF PIRSF028177 8 256 3.4E-68 T 06-07-2017 IPR016874 Tetracenomycin polyketide synthesis O-methyltransferase TcmP GO:0017000|GO:1901106 BWK49_RS15595 4014d242aa04e35bee76d0203eec73a9 273 Gene3D G3DSA:3.40.50.150 18 240 2.8E-40 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS15595 4014d242aa04e35bee76d0203eec73a9 273 SUPERFAMILY SSF53335 17 235 2.9E-53 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS03020 f19b953297475de34caf7ad726b69408 412 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 329 408 1.3E-14 T 06-07-2017 IPR022171 PPE family, C-terminal BWK49_RS03020 f19b953297475de34caf7ad726b69408 412 Pfam PF00823 PPE family 7 162 5.8E-63 T 06-07-2017 IPR000030 PPE family BWK49_RS03020 f19b953297475de34caf7ad726b69408 412 SUPERFAMILY SSF140459 3 174 7.06E-62 T 06-07-2017 BWK49_RS05245 3973bc3ef7c05b24c8cffe36852677b8 538 Gene3D G3DSA:3.30.300.30 428 526 4.7E-27 T 06-07-2017 BWK49_RS05245 3973bc3ef7c05b24c8cffe36852677b8 538 Gene3D G3DSA:3.40.50.980 7 183 4.4E-28 T 06-07-2017 BWK49_RS05245 3973bc3ef7c05b24c8cffe36852677b8 538 Gene3D G3DSA:2.30.38.10 353 426 1.3E-17 T 06-07-2017 BWK49_RS05245 3973bc3ef7c05b24c8cffe36852677b8 538 SUPERFAMILY SSF56801 6 527 1.31E-135 T 06-07-2017 BWK49_RS05245 3973bc3ef7c05b24c8cffe36852677b8 538 Gene3D G3DSA:3.40.50.980 184 338 6.9E-38 T 06-07-2017 BWK49_RS05245 3973bc3ef7c05b24c8cffe36852677b8 538 Pfam PF13193 AMP-binding enzyme C-terminal domain 443 517 3.2E-15 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS05245 3973bc3ef7c05b24c8cffe36852677b8 538 ProSitePatterns PS00455 Putative AMP-binding domain signature. 178 189 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS05245 3973bc3ef7c05b24c8cffe36852677b8 538 Pfam PF00501 AMP-binding enzyme 30 433 1.4E-91 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS25695 8b98deb85a6c16226760fb1a9ba8a152 306 Pfam PF00106 short chain dehydrogenase 19 221 1.2E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS25695 8b98deb85a6c16226760fb1a9ba8a152 306 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 96 107 3.5E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS25695 8b98deb85a6c16226760fb1a9ba8a152 306 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 20 37 3.5E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS25695 8b98deb85a6c16226760fb1a9ba8a152 306 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 201 218 3.5E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS25695 8b98deb85a6c16226760fb1a9ba8a152 306 Gene3D G3DSA:3.40.50.720 15 269 2.3E-57 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS25695 8b98deb85a6c16226760fb1a9ba8a152 306 SUPERFAMILY SSF51735 16 280 1.39E-56 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS26270 864faf3d3acccbe56f9f421e4471c474 112 Pfam PF05305 Protein of unknown function (DUF732) 20 111 1.1E-11 T 06-07-2017 IPR007969 Domain of unknown function DUF732 BWK49_RS18875 017829616217decdef106e11d77d9a52 251 SUPERFAMILY SSF75625 3 246 1.31E-89 T 06-07-2017 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 BWK49_RS18875 017829616217decdef106e11d77d9a52 251 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 238 2.7E-99 T 06-07-2017 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 BWK49_RS18875 017829616217decdef106e11d77d9a52 251 Pfam PF01709 Transcriptional regulator 5 238 1.6E-88 T 06-07-2017 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 BWK49_RS18875 017829616217decdef106e11d77d9a52 251 Gene3D G3DSA:1.10.10.200 1 79 7.3E-32 T 06-07-2017 IPR017856 Integrase, N-terminal zinc-binding domain-like BWK49_RS18875 017829616217decdef106e11d77d9a52 251 Gene3D G3DSA:3.30.1270.10 213 248 2.7E-39 T 06-07-2017 IPR026563 Transcriptional regulator TACO1-like, domain 2 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 BWK49_RS18875 017829616217decdef106e11d77d9a52 251 Gene3D G3DSA:3.30.1270.10 83 137 2.7E-39 T 06-07-2017 IPR026563 Transcriptional regulator TACO1-like, domain 2 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 BWK49_RS18875 017829616217decdef106e11d77d9a52 251 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 3 240 34.648 T 06-07-2017 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 BWK49_RS18875 017829616217decdef106e11d77d9a52 251 Gene3D G3DSA:3.30.70.980 138 205 1.9E-25 T 06-07-2017 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 BWK49_RS24085 73897b76f098ba9ba3e2b6770ad22774 134 SUPERFAMILY SSF49503 43 132 2.64E-25 T 06-07-2017 IPR008972 Cupredoxin BWK49_RS24085 73897b76f098ba9ba3e2b6770ad22774 134 Pfam PF13473 Cupredoxin-like domain 51 132 4.2E-10 T 06-07-2017 IPR028096 EfeO-type cupredoxin-like domain BWK49_RS24085 73897b76f098ba9ba3e2b6770ad22774 134 Gene3D G3DSA:2.60.40.420 42 133 6.3E-28 T 06-07-2017 IPR008972 Cupredoxin BWK49_RS03725 9bd15cbaa39f3cfd9cd920030c8f1743 312 SUPERFAMILY SSF53955 95 266 9.0E-27 T 06-07-2017 IPR023346 Lysozyme-like domain BWK49_RS03725 9bd15cbaa39f3cfd9cd920030c8f1743 312 Pfam PF01464 Transglycosylase SLT domain 165 255 7.8E-6 T 06-07-2017 IPR008258 Transglycosylase SLT domain 1 BWK49_RS03725 9bd15cbaa39f3cfd9cd920030c8f1743 312 Gene3D G3DSA:1.10.530.10 162 259 2.4E-12 T 06-07-2017 BWK49_RS24470 c88d33a263587bdb6ef5a3900c01b9fe 542 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 280 436 1.6E-26 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS24470 c88d33a263587bdb6ef5a3900c01b9fe 542 SUPERFAMILY SSF56645 57 289 1.28E-37 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS24470 c88d33a263587bdb6ef5a3900c01b9fe 542 Gene3D G3DSA:1.20.140.10 272 440 4.0E-36 T 06-07-2017 BWK49_RS24470 c88d33a263587bdb6ef5a3900c01b9fe 542 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 176 269 1.8E-14 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 BWK49_RS24470 c88d33a263587bdb6ef5a3900c01b9fe 542 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 395 414 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 BWK49_RS24470 c88d33a263587bdb6ef5a3900c01b9fe 542 Gene3D G3DSA:2.40.110.10 176 271 1.6E-21 T 06-07-2017 BWK49_RS24470 c88d33a263587bdb6ef5a3900c01b9fe 542 SUPERFAMILY SSF47203 285 438 9.18E-38 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS12230 fe7ee360c42bd960423cff16a18b7fc3 425 PRINTS PR00359 B-class P450 signature 306 333 3.6E-39 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS12230 fe7ee360c42bd960423cff16a18b7fc3 425 PRINTS PR00359 B-class P450 signature 334 349 3.6E-39 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS12230 fe7ee360c42bd960423cff16a18b7fc3 425 PRINTS PR00359 B-class P450 signature 168 183 3.6E-39 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS12230 fe7ee360c42bd960423cff16a18b7fc3 425 PRINTS PR00359 B-class P450 signature 356 365 3.6E-39 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS12230 fe7ee360c42bd960423cff16a18b7fc3 425 PRINTS PR00359 B-class P450 signature 105 116 3.6E-39 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS12230 fe7ee360c42bd960423cff16a18b7fc3 425 PRINTS PR00359 B-class P450 signature 289 300 3.6E-39 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS12230 fe7ee360c42bd960423cff16a18b7fc3 425 PRINTS PR00359 B-class P450 signature 365 376 3.6E-39 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS12230 fe7ee360c42bd960423cff16a18b7fc3 425 PRINTS PR00359 B-class P450 signature 151 167 3.6E-39 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS12230 fe7ee360c42bd960423cff16a18b7fc3 425 Pfam PF00067 Cytochrome P450 290 386 3.8E-17 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS12230 fe7ee360c42bd960423cff16a18b7fc3 425 Gene3D G3DSA:1.10.630.10 24 415 1.6E-97 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS12230 fe7ee360c42bd960423cff16a18b7fc3 425 PRINTS PR00385 P450 superfamily signature 254 271 9.4E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS12230 fe7ee360c42bd960423cff16a18b7fc3 425 PRINTS PR00385 P450 superfamily signature 356 365 9.4E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS12230 fe7ee360c42bd960423cff16a18b7fc3 425 PRINTS PR00385 P450 superfamily signature 289 300 9.4E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS12230 fe7ee360c42bd960423cff16a18b7fc3 425 PRINTS PR00385 P450 superfamily signature 365 376 9.4E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS12230 fe7ee360c42bd960423cff16a18b7fc3 425 SUPERFAMILY SSF48264 28 413 1.44E-76 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS25005 a0a64d76fc836f5d0c91fc0ffa0cd03d 323 SMART SM00922 88 181 3.1E-14 T 06-07-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal BWK49_RS25005 a0a64d76fc836f5d0c91fc0ffa0cd03d 323 SUPERFAMILY SSF51604 74 283 5.9E-45 T 06-07-2017 IPR029065 Enolase C-terminal domain-like BWK49_RS25005 a0a64d76fc836f5d0c91fc0ffa0cd03d 323 Gene3D G3DSA:3.20.20.120 99 315 3.1E-50 T 06-07-2017 IPR029065 Enolase C-terminal domain-like BWK49_RS25005 a0a64d76fc836f5d0c91fc0ffa0cd03d 323 Pfam PF13378 Enolase C-terminal domain-like 100 281 1.7E-28 T 06-07-2017 IPR029065 Enolase C-terminal domain-like BWK49_RS25005 a0a64d76fc836f5d0c91fc0ffa0cd03d 323 Gene3D G3DSA:3.30.390.10 9 98 4.3E-43 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 BWK49_RS25005 a0a64d76fc836f5d0c91fc0ffa0cd03d 323 Hamap MF_00470 o-succinylbenzoate synthase [menC]. 6 286 22.575 T 06-07-2017 IPR010196 o-succinylbenzoate synthase, MenC type1 GO:0000287|GO:0009234|GO:0016836 KEGG: 00010+4.2.1.11|KEGG: 00130+4.2.1.113|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-5837|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 BWK49_RS15610 1e0216dee8f504e84f60570191c6349b 240 Gene3D G3DSA:3.40.225.10 13 211 1.4E-41 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal BWK49_RS15610 1e0216dee8f504e84f60570191c6349b 240 SUPERFAMILY SSF53639 13 208 3.73E-42 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal BWK49_RS15610 1e0216dee8f504e84f60570191c6349b 240 SMART SM01007 13 191 1.4E-36 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal BWK49_RS15610 1e0216dee8f504e84f60570191c6349b 240 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 14 190 7.0E-33 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal BWK49_RS25610 e4b230b1155f996d6b9603530ef873e7 187 Gene3D G3DSA:1.20.1290.10 34 177 1.8E-15 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 BWK49_RS25610 e4b230b1155f996d6b9603530ef873e7 187 Pfam PF02627 Carboxymuconolactone decarboxylase family 44 125 1.9E-6 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 BWK49_RS25610 e4b230b1155f996d6b9603530ef873e7 187 SUPERFAMILY SSF69118 4 180 3.17E-19 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 BWK49_RS16475 d094d64d9c702dcf6cc47d293161afa6 340 Gene3D G3DSA:3.40.50.720 155 310 2.1E-18 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS16475 d094d64d9c702dcf6cc47d293161afa6 340 SUPERFAMILY SSF51735 22 339 4.25E-50 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS16475 d094d64d9c702dcf6cc47d293161afa6 340 PIRSF PIRSF001439 17 339 2.6E-57 T 06-07-2017 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 BWK49_RS16475 d094d64d9c702dcf6cc47d293161afa6 340 Gene3D G3DSA:3.30.1780.10 22 154 2.7E-23 T 06-07-2017 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 BWK49_RS16475 d094d64d9c702dcf6cc47d293161afa6 340 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 24 321 1.5E-31 T 06-07-2017 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 BWK49_RS15775 5939084f9bf5c65680c0afdf8039eaa4 307 Pfam PF07859 alpha/beta hydrolase fold 77 282 1.3E-72 T 06-07-2017 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 BWK49_RS15775 5939084f9bf5c65680c0afdf8039eaa4 307 Gene3D G3DSA:3.40.50.1820 3 305 9.8E-99 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS15775 5939084f9bf5c65680c0afdf8039eaa4 307 SUPERFAMILY SSF53474 17 304 1.54E-75 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS22225 6f97d63d3b00c20cc4daa9c406f040c5 132 Pfam PF16525 Haemophore, haem-binding 38 114 3.1E-28 T 06-07-2017 IPR032407 Haemophore, haem-binding GO:0020037 BWK49_RS22225 6f97d63d3b00c20cc4daa9c406f040c5 132 TIGRFAM TIGR04529 MTB_hemophore: hemophore-related protein, Rv0203/Rv1174c family 40 115 3.8E-24 T 06-07-2017 IPR032407 Haemophore, haem-binding GO:0020037 BWK49_RS02550 afe093e21682c7455de6eea838ddc804 218 Pfam PF14032 PknH-like extracellular domain 33 213 8.3E-38 T 06-07-2017 IPR026954 PknH-like extracellular domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 BWK49_RS13310 762e079ff3ae67d157cef926830d981e 379 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 13 307 1.9E-47 T 06-07-2017 IPR005693 Virulence factor Mce protein BWK49_RS13310 762e079ff3ae67d157cef926830d981e 379 Pfam PF02470 MlaD protein 42 117 2.1E-14 T 06-07-2017 IPR003399 Mce/MlaD BWK49_RS13310 762e079ff3ae67d157cef926830d981e 379 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 49 - T 06-07-2017 IPR010916 TonB box, conserved site BWK49_RS14045 3e03362d70613ac6362ce6331eefc1e4 291 Pfam PF01636 Phosphotransferase enzyme family 40 254 1.1E-24 T 06-07-2017 IPR002575 Aminoglycoside phosphotransferase BWK49_RS14045 3e03362d70613ac6362ce6331eefc1e4 291 SUPERFAMILY SSF56112 24 255 2.48E-28 T 06-07-2017 IPR011009 Protein kinase-like domain BWK49_RS14045 3e03362d70613ac6362ce6331eefc1e4 291 Gene3D G3DSA:3.90.1200.10 119 265 2.1E-19 T 06-07-2017 BWK49_RS20340 2f96c6f0e27bec08ab9f992f5ba24510 264 SUPERFAMILY SSF53474 13 257 4.88E-39 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS20340 2f96c6f0e27bec08ab9f992f5ba24510 264 Pfam PF12697 Alpha/beta hydrolase family 18 241 1.5E-21 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS20340 2f96c6f0e27bec08ab9f992f5ba24510 264 Gene3D G3DSA:3.40.50.1820 17 256 5.5E-39 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS07660 0e8eb62d28eb469cd72818acb1ac5649 289 SUPERFAMILY SSF52151 4 81 1.02E-29 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 BWK49_RS07660 0e8eb62d28eb469cd72818acb1ac5649 289 SUPERFAMILY SSF52151 116 219 1.02E-29 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 BWK49_RS07660 0e8eb62d28eb469cd72818acb1ac5649 289 Pfam PF01734 Patatin-like phospholipase 7 205 1.3E-19 T 06-07-2017 IPR002641 Patatin/Phospholipase A2-related GO:0006629 BWK49_RS07660 0e8eb62d28eb469cd72818acb1ac5649 289 Gene3D G3DSA:3.40.1090.10 4 201 5.8E-9 T 06-07-2017 BWK49_RS23180 1e8a1ef8ed9eeca132f5409cc0e199b0 546 Gene3D G3DSA:3.90.226.10 291 546 3.5E-99 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS23180 1e8a1ef8ed9eeca132f5409cc0e199b0 546 Pfam PF01039 Carboxyl transferase domain 47 544 7.0E-200 T 06-07-2017 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 BWK49_RS23180 1e8a1ef8ed9eeca132f5409cc0e199b0 546 SUPERFAMILY SSF52096 25 275 1.39E-74 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS23180 1e8a1ef8ed9eeca132f5409cc0e199b0 546 Gene3D G3DSA:3.90.226.10 19 276 9.9E-78 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS23180 1e8a1ef8ed9eeca132f5409cc0e199b0 546 SUPERFAMILY SSF52096 292 546 8.37E-90 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS19400 5e2145d3b92dff9642971971c1b65be1 161 Pfam PF11292 Protein of unknown function (DUF3093) 12 159 7.1E-50 T 06-07-2017 IPR021443 Protein of unknown function DUF3093 BWK49_RS24950 106ff8b6d1ae9f13e6b63f55c2ca1285 273 SUPERFAMILY SSF52096 13 273 7.7E-73 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS24950 106ff8b6d1ae9f13e6b63f55c2ca1285 273 Pfam PF00378 Enoyl-CoA hydratase/isomerase 14 272 1.8E-54 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 BWK49_RS24950 106ff8b6d1ae9f13e6b63f55c2ca1285 273 Gene3D G3DSA:3.90.226.10 14 271 1.1E-75 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS19770 0cf1f425c900dd849f4702897e9147c2 216 Gene3D G3DSA:1.10.357.10 12 212 1.0E-23 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS19770 0cf1f425c900dd849f4702897e9147c2 216 SUPERFAMILY SSF46689 13 90 2.51E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS19605 c52b45d8b9cb8ba41d772861a2b7e002 143 Pfam PF07858 Limonene-1,2-epoxide hydrolase catalytic domain 10 129 8.9E-54 T 06-07-2017 IPR013100 Limonene-1,2-epoxide hydrolase BWK49_RS19605 c52b45d8b9cb8ba41d772861a2b7e002 143 SUPERFAMILY SSF54427 11 135 2.25E-36 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS19605 c52b45d8b9cb8ba41d772861a2b7e002 143 Gene3D G3DSA:3.10.450.50 8 130 8.7E-44 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS07740 1bb20a0639e0135fe6206e1e25f5e2f0 164 PIRSF PIRSF006092 1 163 7.4E-31 T 06-07-2017 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 BWK49_RS07740 1bb20a0639e0135fe6206e1e25f5e2f0 164 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 8 158 1.8E-44 T 06-07-2017 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 BWK49_RS07740 1bb20a0639e0135fe6206e1e25f5e2f0 164 Gene3D G3DSA:3.10.50.30 79 162 2.2E-13 T 06-07-2017 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 BWK49_RS07740 1bb20a0639e0135fe6206e1e25f5e2f0 164 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 124 140 - T 06-07-2017 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 BWK49_RS07740 1bb20a0639e0135fe6206e1e25f5e2f0 164 Gene3D G3DSA:1.10.287.180 6 76 2.6E-26 T 06-07-2017 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 BWK49_RS07740 1bb20a0639e0135fe6206e1e25f5e2f0 164 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 82 160 2.7E-13 T 06-07-2017 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 BWK49_RS07740 1bb20a0639e0135fe6206e1e25f5e2f0 164 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 20 50 - T 06-07-2017 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 BWK49_RS07740 1bb20a0639e0135fe6206e1e25f5e2f0 164 SUPERFAMILY SSF46557 7 78 7.32E-23 T 06-07-2017 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 BWK49_RS07740 1bb20a0639e0135fe6206e1e25f5e2f0 164 Hamap MF_00105 Transcription elongation factor GreA [greA]. 5 160 28.116 T 06-07-2017 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 BWK49_RS07740 1bb20a0639e0135fe6206e1e25f5e2f0 164 Pfam PF03449 Transcription elongation factor, N-terminal 8 76 1.2E-24 T 06-07-2017 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 BWK49_RS07740 1bb20a0639e0135fe6206e1e25f5e2f0 164 SUPERFAMILY SSF54534 82 160 9.03E-11 T 06-07-2017 BWK49_RS13225 7a47c06a921c7f1c088c43f475871676 502 Gene3D G3DSA:1.20.1250.20 27 212 3.9E-26 T 06-07-2017 BWK49_RS13225 7a47c06a921c7f1c088c43f475871676 502 Gene3D G3DSA:1.20.1250.20 277 482 2.2E-8 T 06-07-2017 BWK49_RS13225 7a47c06a921c7f1c088c43f475871676 502 Pfam PF07690 Major Facilitator Superfamily 35 421 4.9E-40 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 BWK49_RS13225 7a47c06a921c7f1c088c43f475871676 502 SUPERFAMILY SSF103473 260 481 3.4E-51 T 06-07-2017 IPR020846 Major facilitator superfamily domain BWK49_RS13225 7a47c06a921c7f1c088c43f475871676 502 SUPERFAMILY SSF103473 10 212 3.4E-51 T 06-07-2017 IPR020846 Major facilitator superfamily domain BWK49_RS19245 7e3fdaf544714e1fe48f98308ec1a2ae 256 SUPERFAMILY SSF81923 98 237 3.92E-24 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 BWK49_RS19245 7e3fdaf544714e1fe48f98308ec1a2ae 256 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 189 239 4.9E-6 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 BWK49_RS19245 7e3fdaf544714e1fe48f98308ec1a2ae 256 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 110 159 1.7E-6 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 BWK49_RS19245 7e3fdaf544714e1fe48f98308ec1a2ae 256 Gene3D G3DSA:1.10.1780.10 96 237 9.3E-33 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 BWK49_RS13270 89d65e0442a173afd52aa617b3088030 283 Pfam PF09754 PAC2 family 13 230 5.1E-51 T 06-07-2017 IPR019151 Proteasome assembly chaperone 2 BWK49_RS13270 89d65e0442a173afd52aa617b3088030 283 PIRSF PIRSF028754 1 281 8.8E-123 T 06-07-2017 IPR008492 Protein of unknown function DUF774 BWK49_RS13270 89d65e0442a173afd52aa617b3088030 283 SUPERFAMILY SSF159659 2 253 1.44E-88 T 06-07-2017 BWK49_RS19620 c45d5f118c75f59e10f3874910bdb400 275 Pfam PF04012 PspA/IM30 family 3 241 1.8E-60 T 06-07-2017 IPR007157 PspA/IM30 BWK49_RS13030 eea814f8c0ec188b752c9651d3e72522 143 ProDom PD006745 MRAZ YABB DIVISION CELL 3D-STRUCTURE UNCHARACTERIZED BCR SIMILAR PROTEIN 1 128 3.0E-70 T 06-07-2017 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 BWK49_RS13030 eea814f8c0ec188b752c9651d3e72522 143 TIGRFAM TIGR00242 TIGR00242: division/cell wall cluster transcriptional repressor MraZ 2 136 4.0E-32 T 06-07-2017 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 BWK49_RS13030 eea814f8c0ec188b752c9651d3e72522 143 Hamap MF_01008 Transcriptional regulator MraZ [mraZ]. 1 143 48.708 T 06-07-2017 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 BWK49_RS13030 eea814f8c0ec188b752c9651d3e72522 143 Pfam PF02381 MraZ protein, putative antitoxin-like 73 140 3.3E-23 T 06-07-2017 IPR020603 MraZ domain BWK49_RS13030 eea814f8c0ec188b752c9651d3e72522 143 Pfam PF02381 MraZ protein, putative antitoxin-like 2 71 1.3E-20 T 06-07-2017 IPR020603 MraZ domain BWK49_RS13030 eea814f8c0ec188b752c9651d3e72522 143 SUPERFAMILY SSF89447 2 134 9.42E-43 T 06-07-2017 BWK49_RS06060 52e8c90646705ba7193468970e4b1de4 365 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 4 113 1.7E-8 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS06060 52e8c90646705ba7193468970e4b1de4 365 Gene3D G3DSA:1.10.540.10 4 114 1.1E-11 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS06060 52e8c90646705ba7193468970e4b1de4 365 Gene3D G3DSA:2.40.110.10 116 210 1.0E-31 T 06-07-2017 BWK49_RS06060 52e8c90646705ba7193468970e4b1de4 365 SUPERFAMILY SSF56645 4 232 5.24E-56 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS06060 52e8c90646705ba7193468970e4b1de4 365 Gene3D G3DSA:1.20.140.10 211 364 3.1E-22 T 06-07-2017 BWK49_RS06060 52e8c90646705ba7193468970e4b1de4 365 SUPERFAMILY SSF47203 220 361 8.94E-18 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS06060 52e8c90646705ba7193468970e4b1de4 365 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 220 360 3.5E-11 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS06060 52e8c90646705ba7193468970e4b1de4 365 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 117 208 3.4E-21 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 BWK49_RS07440 79c8ee97631f66a4e57a971f35d70885 221 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 103 181 2.2E-17 T 06-07-2017 IPR020057 Ribosomal protein L25, beta domain BWK49_RS07440 79c8ee97631f66a4e57a971f35d70885 221 Gene3D G3DSA:2.170.120.20 100 187 7.8E-19 T 06-07-2017 IPR020057 Ribosomal protein L25, beta domain BWK49_RS07440 79c8ee97631f66a4e57a971f35d70885 221 Gene3D G3DSA:2.40.240.10 8 97 4.7E-29 T 06-07-2017 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 BWK49_RS07440 79c8ee97631f66a4e57a971f35d70885 221 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 7 183 23.78 T 06-07-2017 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 BWK49_RS07440 79c8ee97631f66a4e57a971f35d70885 221 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 13 94 1.0E-39 T 06-07-2017 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 BWK49_RS07440 79c8ee97631f66a4e57a971f35d70885 221 SUPERFAMILY SSF50715 8 187 1.08E-47 T 06-07-2017 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 BWK49_RS07440 79c8ee97631f66a4e57a971f35d70885 221 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 9 180 1.8E-56 T 06-07-2017 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 BWK49_RS07440 79c8ee97631f66a4e57a971f35d70885 221 Pfam PF01386 Ribosomal L25p family 9 95 1.3E-23 T 06-07-2017 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 BWK49_RS13965 67cd777e11758749ab443897ccbd0bc0 367 Gene3D G3DSA:3.40.50.300 118 234 2.5E-8 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS13965 67cd777e11758749ab443897ccbd0bc0 367 Pfam PF05621 Bacterial TniB protein 107 342 4.9E-30 T 06-07-2017 IPR008868 Bacterial TniB BWK49_RS13965 67cd777e11758749ab443897ccbd0bc0 367 SUPERFAMILY SSF52540 120 349 3.54E-12 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS21215 c397c454f44982a53564526af9a21d23 159 Pfam PF03073 TspO/MBR family 13 155 2.5E-31 T 06-07-2017 IPR004307 TspO/MBR-related protein GO:0016021 BWK49_RS21215 c397c454f44982a53564526af9a21d23 159 PIRSF PIRSF005859 1 159 4.7E-31 T 06-07-2017 IPR004307 TspO/MBR-related protein GO:0016021 BWK49_RS10735 510ce1d4508a145b2242129f9b9c4765 133 Gene3D G3DSA:1.10.10.10 8 96 3.3E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS10735 510ce1d4508a145b2242129f9b9c4765 133 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 70 85 1.2E-13 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 BWK49_RS10735 510ce1d4508a145b2242129f9b9c4765 133 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 42 53 1.2E-13 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 BWK49_RS10735 510ce1d4508a145b2242129f9b9c4765 133 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 23 38 1.2E-13 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 BWK49_RS10735 510ce1d4508a145b2242129f9b9c4765 133 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 55 70 1.2E-13 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 BWK49_RS10735 510ce1d4508a145b2242129f9b9c4765 133 Pfam PF01022 Bacterial regulatory protein, arsR family 28 72 2.4E-13 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 BWK49_RS10735 510ce1d4508a145b2242129f9b9c4765 133 SUPERFAMILY SSF46785 11 93 8.62E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS10735 510ce1d4508a145b2242129f9b9c4765 133 SMART SM00418 21 99 5.4E-28 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 BWK49_RS09850 072d057d363ffba8df39f48372e462e6 131 SUPERFAMILY SSF46458 6 129 7.4E-35 T 06-07-2017 IPR009050 Globin-like BWK49_RS09850 072d057d363ffba8df39f48372e462e6 131 Gene3D G3DSA:1.10.490.10 5 129 7.6E-44 T 06-07-2017 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 BWK49_RS09850 072d057d363ffba8df39f48372e462e6 131 Pfam PF01152 Bacterial-like globin 7 124 1.2E-41 T 06-07-2017 IPR001486 Truncated hemoglobin GO:0019825 BWK49_RS24880 e6aa4104607fa00961bccb36aacbe6e0 289 SUPERFAMILY SSF51556 5 289 3.14E-39 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS24880 e6aa4104607fa00961bccb36aacbe6e0 289 Pfam PF04909 Amidohydrolase 9 289 2.4E-32 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 BWK49_RS24880 e6aa4104607fa00961bccb36aacbe6e0 289 Gene3D G3DSA:3.20.20.140 5 289 8.8E-44 T 06-07-2017 BWK49_RS10390 dc2750ead7adbea3d83958f9b290f80f 213 Pfam PF00665 Integrase core domain 124 193 3.8E-7 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 BWK49_RS10390 dc2750ead7adbea3d83958f9b290f80f 213 Pfam PF13384 Homeodomain-like domain 2 48 1.6E-7 T 06-07-2017 BWK49_RS22500 dc2750ead7adbea3d83958f9b290f80f 213 Pfam PF00665 Integrase core domain 124 193 3.8E-7 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 BWK49_RS22500 dc2750ead7adbea3d83958f9b290f80f 213 Pfam PF13384 Homeodomain-like domain 2 48 1.6E-7 T 06-07-2017 BWK49_RS10495 dc2750ead7adbea3d83958f9b290f80f 213 Pfam PF00665 Integrase core domain 124 193 3.8E-7 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 BWK49_RS10495 dc2750ead7adbea3d83958f9b290f80f 213 Pfam PF13384 Homeodomain-like domain 2 48 1.6E-7 T 06-07-2017 BWK49_RS01370 8eb941f0646375c93660ade5c63b00b2 1952 SUPERFAMILY SSF52540 1724 1851 1.0E-8 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS01370 8eb941f0646375c93660ade5c63b00b2 1952 Gene3D G3DSA:3.40.50.300 1719 1853 5.2E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS01370 8eb941f0646375c93660ade5c63b00b2 1952 Gene3D G3DSA:3.40.50.300 594 771 1.9E-25 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS01370 8eb941f0646375c93660ade5c63b00b2 1952 SUPERFAMILY SSF55464 194 448 2.61E-66 T 06-07-2017 BWK49_RS01370 8eb941f0646375c93660ade5c63b00b2 1952 SUPERFAMILY SSF55464 7 102 2.61E-66 T 06-07-2017 BWK49_RS01370 8eb941f0646375c93660ade5c63b00b2 1952 SUPERFAMILY SSF52540 824 999 1.63E-22 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS01370 8eb941f0646375c93660ade5c63b00b2 1952 SUPERFAMILY SSF52540 725 789 1.63E-22 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS01370 8eb941f0646375c93660ade5c63b00b2 1952 Pfam PF13604 AAA domain 600 806 1.9E-57 T 06-07-2017 BWK49_RS01370 8eb941f0646375c93660ade5c63b00b2 1952 Pfam PF13604 AAA domain 1728 1854 6.9E-11 T 06-07-2017 BWK49_RS01370 8eb941f0646375c93660ade5c63b00b2 1952 Pfam PF08751 TrwC relaxase 15 437 1.7E-88 T 06-07-2017 IPR014862 TrwC relaxase BWK49_RS01370 8eb941f0646375c93660ade5c63b00b2 1952 SUPERFAMILY SSF52540 597 760 1.73E-24 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS04445 68efc64ffac73ffce2a382a6e845e76b 467 Pfam PF12696 TraM recognition site of TraD and TraG 310 411 9.8E-10 T 06-07-2017 IPR032689 TraD/TraG, TraM recognition site BWK49_RS04445 68efc64ffac73ffce2a382a6e845e76b 467 Gene3D G3DSA:3.40.50.300 261 448 6.4E-15 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS04445 68efc64ffac73ffce2a382a6e845e76b 467 Gene3D G3DSA:3.40.50.300 16 90 6.4E-15 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS04445 68efc64ffac73ffce2a382a6e845e76b 467 SUPERFAMILY SSF52540 9 404 8.14E-12 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS08160 f826bcae72025938ea0aee44f36d5d95 254 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 196 0.004 T 06-07-2017 BWK49_RS08160 f826bcae72025938ea0aee44f36d5d95 254 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 147 175 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS08160 f826bcae72025938ea0aee44f36d5d95 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 148 2.0E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS08160 f826bcae72025938ea0aee44f36d5d95 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 74 85 2.0E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS08160 f826bcae72025938ea0aee44f36d5d95 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 2.0E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS08160 f826bcae72025938ea0aee44f36d5d95 254 SUPERFAMILY SSF51735 7 250 3.97E-56 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS08160 f826bcae72025938ea0aee44f36d5d95 254 Gene3D G3DSA:3.40.50.720 2 250 1.5E-64 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS08160 f826bcae72025938ea0aee44f36d5d95 254 Pfam PF00106 short chain dehydrogenase 7 203 9.4E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS08160 f826bcae72025938ea0aee44f36d5d95 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 9.3E-27 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS08160 f826bcae72025938ea0aee44f36d5d95 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 9.3E-27 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS08160 f826bcae72025938ea0aee44f36d5d95 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 9.3E-27 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS08160 f826bcae72025938ea0aee44f36d5d95 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 9.3E-27 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS08160 f826bcae72025938ea0aee44f36d5d95 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 9.3E-27 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS08160 f826bcae72025938ea0aee44f36d5d95 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 9.3E-27 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS11635 c4d3464c623d8a412edf45701e04796f 274 SUPERFAMILY SSF161098 5 274 7.33E-60 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS11635 c4d3464c623d8a412edf45701e04796f 274 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 267 1.0E-19 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS11635 c4d3464c623d8a412edf45701e04796f 274 Gene3D G3DSA:1.10.3720.10 4 262 1.1E-57 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS18085 2c6a27d050468bbb5b91105eab531ce5 374 PIRSF PIRSF036915 1 369 1.9E-165 T 06-07-2017 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 BWK49_RS18085 2c6a27d050468bbb5b91105eab531ce5 374 Gene3D G3DSA:3.20.20.70 5 360 3.3E-116 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 BWK49_RS18085 2c6a27d050468bbb5b91105eab531ce5 374 ProSitePatterns PS01054 Transaldolase signature 1. 43 51 - T 06-07-2017 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336 BWK49_RS18085 2c6a27d050468bbb5b91105eab531ce5 374 SUPERFAMILY SSF51569 7 361 3.3E-75 T 06-07-2017 BWK49_RS18085 2c6a27d050468bbb5b91105eab531ce5 374 Hamap MF_00493 Transaldolase [tal]. 1 374 148.438 T 06-07-2017 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 BWK49_RS18085 2c6a27d050468bbb5b91105eab531ce5 374 Pfam PF00923 Transaldolase 17 362 2.6E-82 T 06-07-2017 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336 BWK49_RS18085 2c6a27d050468bbb5b91105eab531ce5 374 TIGRFAM TIGR00876 tal_mycobact: transaldolase 13 361 1.6E-154 T 06-07-2017 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 BWK49_RS06575 0e70d464553247f28f269b05a1bfaec2 160 SUPERFAMILY SSF53218 6 153 4.97E-38 T 06-07-2017 IPR001453 MoaB/Mog domain BWK49_RS06575 0e70d464553247f28f269b05a1bfaec2 160 SMART SM00852 7 149 6.4E-17 T 06-07-2017 IPR001453 MoaB/Mog domain BWK49_RS06575 0e70d464553247f28f269b05a1bfaec2 160 Pfam PF00994 Probable molybdopterin binding domain 8 147 3.7E-25 T 06-07-2017 IPR001453 MoaB/Mog domain BWK49_RS06575 0e70d464553247f28f269b05a1bfaec2 160 Gene3D G3DSA:3.40.980.10 5 155 4.9E-48 T 06-07-2017 IPR001453 MoaB/Mog domain BWK49_RS06575 0e70d464553247f28f269b05a1bfaec2 160 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 6 142 9.3E-33 T 06-07-2017 IPR001453 MoaB/Mog domain BWK49_RS21415 0724a70b3eccbbf2fc29ac54c41ee91e 255 SUPERFAMILY SSF51735 5 251 1.76E-56 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS21415 0724a70b3eccbbf2fc29ac54c41ee91e 255 Pfam PF00106 short chain dehydrogenase 6 202 9.0E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS21415 0724a70b3eccbbf2fc29ac54c41ee91e 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.2E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS21415 0724a70b3eccbbf2fc29ac54c41ee91e 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 1.2E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS21415 0724a70b3eccbbf2fc29ac54c41ee91e 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 1.2E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS21415 0724a70b3eccbbf2fc29ac54c41ee91e 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 1.2E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS21415 0724a70b3eccbbf2fc29ac54c41ee91e 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 1.2E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS21415 0724a70b3eccbbf2fc29ac54c41ee91e 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 1.2E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS21415 0724a70b3eccbbf2fc29ac54c41ee91e 255 Gene3D G3DSA:3.40.50.720 2 250 6.4E-60 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS21415 0724a70b3eccbbf2fc29ac54c41ee91e 255 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 148 176 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS21415 0724a70b3eccbbf2fc29ac54c41ee91e 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 161 180 3.5E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS21415 0724a70b3eccbbf2fc29ac54c41ee91e 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 3.5E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS21415 0724a70b3eccbbf2fc29ac54c41ee91e 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 3.5E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27665 85120053a84a5ffa27b51c1305f56bc4 165 SUPERFAMILY SSF56300 2 162 2.46E-32 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like BWK49_RS27665 85120053a84a5ffa27b51c1305f56bc4 165 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 2 151 1.3E-26 T 06-07-2017 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 BWK49_RS27665 85120053a84a5ffa27b51c1305f56bc4 165 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 2 156 1.5E-27 T 06-07-2017 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 BWK49_RS27665 85120053a84a5ffa27b51c1305f56bc4 165 Gene3D G3DSA:3.60.21.10 2 155 4.1E-28 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like BWK49_RS24315 4242f86f129c8730ecac71b4c734ff1e 100 Pfam PF00276 Ribosomal protein L23 9 91 6.3E-32 T 06-07-2017 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 BWK49_RS24315 4242f86f129c8730ecac71b4c734ff1e 100 Gene3D G3DSA:3.30.70.330 6 96 7.8E-35 T 06-07-2017 IPR012677 Nucleotide-binding alpha-beta plait domain GO:0000166 BWK49_RS24315 4242f86f129c8730ecac71b4c734ff1e 100 SUPERFAMILY SSF54189 5 95 6.47E-33 T 06-07-2017 IPR012678 Ribosomal protein L23/L15e core domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS24315 4242f86f129c8730ecac71b4c734ff1e 100 ProSitePatterns PS00050 Ribosomal protein L23 signature. 80 95 - T 06-07-2017 IPR001014 Ribosomal protein L23/L25, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 BWK49_RS24315 4242f86f129c8730ecac71b4c734ff1e 100 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 8 98 21.829 T 06-07-2017 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 BWK49_RS28580 b959c12dfd2b6f08667955eb87e6b175 613 Pfam PF00501 AMP-binding enzyme 44 497 1.8E-69 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS28580 b959c12dfd2b6f08667955eb87e6b175 613 Gene3D G3DSA:2.30.38.10 397 488 3.1E-17 T 06-07-2017 BWK49_RS28580 b959c12dfd2b6f08667955eb87e6b175 613 SUPERFAMILY SSF56801 28 608 9.42E-100 T 06-07-2017 BWK49_RS28580 b959c12dfd2b6f08667955eb87e6b175 613 Gene3D G3DSA:3.30.300.30 489 605 8.8E-16 T 06-07-2017 BWK49_RS28580 b959c12dfd2b6f08667955eb87e6b175 613 Gene3D G3DSA:3.40.50.980 28 198 5.0E-26 T 06-07-2017 BWK49_RS28580 b959c12dfd2b6f08667955eb87e6b175 613 Gene3D G3DSA:3.40.50.980 199 366 3.2E-24 T 06-07-2017 BWK49_RS20740 c5aa66e421c19740e116d4a86874ecbc 210 Pfam PF07884 Vitamin K epoxide reductase family 27 159 3.4E-33 T 06-07-2017 IPR012932 Vitamin K epoxide reductase Reactome: R-HSA-6806664 BWK49_RS20740 c5aa66e421c19740e116d4a86874ecbc 210 SMART SM00756 22 163 1.5E-61 T 06-07-2017 IPR012932 Vitamin K epoxide reductase Reactome: R-HSA-6806664 BWK49_RS19700 e1be5f473c65cbcb24e0a6f9f052c370 370 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 14 112 2.7E-14 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS19700 e1be5f473c65cbcb24e0a6f9f052c370 370 Gene3D G3DSA:1.10.540.10 13 113 3.8E-17 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS19700 e1be5f473c65cbcb24e0a6f9f052c370 370 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 229 363 3.2E-26 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS19700 e1be5f473c65cbcb24e0a6f9f052c370 370 SUPERFAMILY SSF47203 226 364 3.22E-35 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS19700 e1be5f473c65cbcb24e0a6f9f052c370 370 Gene3D G3DSA:1.20.140.10 228 364 6.7E-35 T 06-07-2017 BWK49_RS19700 e1be5f473c65cbcb24e0a6f9f052c370 370 SUPERFAMILY SSF56645 10 209 4.97E-23 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS20620 f49ec87c93a90bff3dd4e66d54bd1ece 69 SUPERFAMILY SSF54631 1 49 2.23E-11 T 06-07-2017 BWK49_RS20620 f49ec87c93a90bff3dd4e66d54bd1ece 69 Pfam PF00571 CBS domain 1 49 8.3E-8 T 06-07-2017 IPR000644 CBS domain BWK49_RS20620 f49ec87c93a90bff3dd4e66d54bd1ece 69 Gene3D G3DSA:3.10.580.10 1 49 1.1E-9 T 06-07-2017 BWK49_RS27490 b8c01639f7627c9cde3889a2c5dba5b2 327 Pfam PF02678 Pirin 51 146 2.1E-29 T 06-07-2017 IPR003829 Pirin, N-terminal domain BWK49_RS27490 b8c01639f7627c9cde3889a2c5dba5b2 327 SUPERFAMILY SSF51182 24 315 5.09E-77 T 06-07-2017 IPR011051 RmlC-like cupin domain BWK49_RS27490 b8c01639f7627c9cde3889a2c5dba5b2 327 Pfam PF05726 Pirin C-terminal cupin domain 202 311 6.1E-29 T 06-07-2017 IPR008778 Pirin, C-terminal domain BWK49_RS27490 b8c01639f7627c9cde3889a2c5dba5b2 327 PIRSF PIRSF006232 22 317 3.4E-82 T 06-07-2017 IPR012093 Pirin BWK49_RS27490 b8c01639f7627c9cde3889a2c5dba5b2 327 Gene3D G3DSA:2.60.120.10 23 284 5.6E-73 T 06-07-2017 IPR014710 RmlC-like jelly roll fold BWK49_RS19085 f3b1337c44906fc13a800a960ebbb1b1 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 1.6E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS19085 f3b1337c44906fc13a800a960ebbb1b1 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 74 85 1.6E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS19085 f3b1337c44906fc13a800a960ebbb1b1 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 1.6E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS19085 f3b1337c44906fc13a800a960ebbb1b1 263 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 248 7.8E-61 T 06-07-2017 BWK49_RS19085 f3b1337c44906fc13a800a960ebbb1b1 263 Gene3D G3DSA:3.40.50.720 8 249 1.6E-73 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS19085 f3b1337c44906fc13a800a960ebbb1b1 263 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS19085 f3b1337c44906fc13a800a960ebbb1b1 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 1.9E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS19085 f3b1337c44906fc13a800a960ebbb1b1 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 1.9E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS19085 f3b1337c44906fc13a800a960ebbb1b1 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 1.9E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS19085 f3b1337c44906fc13a800a960ebbb1b1 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 1.9E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS19085 f3b1337c44906fc13a800a960ebbb1b1 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 1.9E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS19085 f3b1337c44906fc13a800a960ebbb1b1 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 1.9E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS19085 f3b1337c44906fc13a800a960ebbb1b1 263 SUPERFAMILY SSF51735 9 249 6.18E-71 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS15300 f7ea629e126dacf12f229ae8901d77c9 1387 TIGRFAM TIGR03925 T7SS_EccC_b: type VII secretion protein EccCb 790 1380 2.2E-164 T 06-07-2017 IPR023837 EccCb-like, Actinobacteria BWK49_RS15300 f7ea629e126dacf12f229ae8901d77c9 1387 Pfam PF01580 FtsK/SpoIIIE family 819 1092 3.9E-75 T 06-07-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 BWK49_RS15300 f7ea629e126dacf12f229ae8901d77c9 1387 Pfam PF01580 FtsK/SpoIIIE family 465 672 3.7E-22 T 06-07-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 BWK49_RS15300 f7ea629e126dacf12f229ae8901d77c9 1387 SUPERFAMILY SSF52540 464 672 1.36E-23 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS15300 f7ea629e126dacf12f229ae8901d77c9 1387 TIGRFAM TIGR03924 T7SS_EccC_a: type VII secretion protein EccCa 25 716 1.7E-214 T 06-07-2017 IPR023836 EccCa-like, Actinobacteria BWK49_RS15300 f7ea629e126dacf12f229ae8901d77c9 1387 SMART SM00382 491 669 0.47 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS15300 f7ea629e126dacf12f229ae8901d77c9 1387 SMART SM00382 1166 1345 4.6 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS15300 f7ea629e126dacf12f229ae8901d77c9 1387 SMART SM00382 864 1064 0.026 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS15300 f7ea629e126dacf12f229ae8901d77c9 1387 Gene3D G3DSA:3.40.50.300 865 1054 1.2E-7 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS15300 f7ea629e126dacf12f229ae8901d77c9 1387 Gene3D G3DSA:3.40.50.300 491 674 1.7E-23 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS15300 f7ea629e126dacf12f229ae8901d77c9 1387 SUPERFAMILY SSF52540 805 1056 6.86E-16 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS17855 609cb959832f0769871daf8bea08f696 314 ProDom PD040491 SCO1799 RV1486C/MT1533 MB1522C CGL1536 ML1804 MAV321 1 304 5.0E-143 T 06-07-2017 BWK49_RS08115 ed8e7da37a34998df4106c5fbb04e54d 263 Gene3D G3DSA:3.90.226.10 8 199 1.5E-62 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS08115 ed8e7da37a34998df4106c5fbb04e54d 263 Gene3D G3DSA:1.10.12.10 203 263 2.3E-18 T 06-07-2017 IPR014748 Crontonase, C-terminal BWK49_RS08115 ed8e7da37a34998df4106c5fbb04e54d 263 SUPERFAMILY SSF52096 8 262 5.94E-76 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS08115 ed8e7da37a34998df4106c5fbb04e54d 263 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 101 121 - T 06-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 BWK49_RS08115 ed8e7da37a34998df4106c5fbb04e54d 263 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 262 2.5E-59 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 BWK49_RS19575 e073157e882e43d59e533b04a84995c3 350 Gene3D G3DSA:3.30.250.10 270 328 1.4E-28 T 06-07-2017 IPR023400 DNA recombination and repair protein RecA, C-terminal BWK49_RS19575 e073157e882e43d59e533b04a84995c3 350 SUPERFAMILY SSF52540 6 269 6.09E-69 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS19575 e073157e882e43d59e533b04a84995c3 350 Hamap MF_00268 Protein RecA [recA]. 7 331 52.572 T 06-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 BWK49_RS19575 e073157e882e43d59e533b04a84995c3 350 PRINTS PR00142 RecA protein signature 95 124 4.1E-84 T 06-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 BWK49_RS19575 e073157e882e43d59e533b04a84995c3 350 PRINTS PR00142 RecA protein signature 245 274 4.1E-84 T 06-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 BWK49_RS19575 e073157e882e43d59e533b04a84995c3 350 PRINTS PR00142 RecA protein signature 299 316 4.1E-84 T 06-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 BWK49_RS19575 e073157e882e43d59e533b04a84995c3 350 PRINTS PR00142 RecA protein signature 167 196 4.1E-84 T 06-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 BWK49_RS19575 e073157e882e43d59e533b04a84995c3 350 PRINTS PR00142 RecA protein signature 129 158 4.1E-84 T 06-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 BWK49_RS19575 e073157e882e43d59e533b04a84995c3 350 PRINTS PR00142 RecA protein signature 212 240 4.1E-84 T 06-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 BWK49_RS19575 e073157e882e43d59e533b04a84995c3 350 ProSitePatterns PS00321 recA signature. 215 223 - T 06-07-2017 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 BWK49_RS19575 e073157e882e43d59e533b04a84995c3 350 Gene3D G3DSA:3.40.50.300 28 269 2.9E-87 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS19575 e073157e882e43d59e533b04a84995c3 350 Pfam PF00154 recA bacterial DNA recombination protein 9 270 8.3E-143 T 06-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 BWK49_RS19575 e073157e882e43d59e533b04a84995c3 350 SUPERFAMILY SSF54752 270 328 2.62E-20 T 06-07-2017 IPR023400 DNA recombination and repair protein RecA, C-terminal BWK49_RS19575 e073157e882e43d59e533b04a84995c3 350 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 6 326 2.8E-173 T 06-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 BWK49_RS19575 e073157e882e43d59e533b04a84995c3 350 SMART SM00382 59 230 3.3E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS15185 ffbb1b5574a3b86957de9f854cd62bb9 107 Pfam PF05305 Protein of unknown function (DUF732) 6 104 8.4E-21 T 06-07-2017 IPR007969 Domain of unknown function DUF732 BWK49_RS07290 96cc5f8c964953a46c87f504684c674f 488 SUPERFAMILY SSF52540 294 475 5.32E-28 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS07290 96cc5f8c964953a46c87f504684c674f 488 Pfam PF02706 Chain length determinant protein 2 131 1.3E-10 T 06-07-2017 IPR003856 Lipopolysaccharide biosynthesis GO:0009103|GO:0016020 BWK49_RS07290 96cc5f8c964953a46c87f504684c674f 488 Gene3D G3DSA:3.40.50.300 293 471 3.1E-26 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS07290 96cc5f8c964953a46c87f504684c674f 488 Pfam PF13614 AAA domain 303 425 1.8E-9 T 06-07-2017 IPR025669 AAA domain BWK49_RS10200 5fa53340f3b0869d0ee04688ecfa66a8 200 SUPERFAMILY SSF50118 93 195 3.05E-9 T 06-07-2017 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor BWK49_RS10200 5fa53340f3b0869d0ee04688ecfa66a8 200 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 95 194 2.3E-9 T 06-07-2017 IPR003477 mRNA interferase PemK-like protein GO:0003677 BWK49_RS21955 1bf87e8456fb175163c3c6dfb2b96d98 303 Pfam PF00682 HMGL-like 6 280 9.3E-39 T 06-07-2017 IPR000891 Pyruvate carboxyltransferase GO:0003824 BWK49_RS21955 1bf87e8456fb175163c3c6dfb2b96d98 303 Gene3D G3DSA:3.20.20.70 4 292 1.2E-61 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 BWK49_RS21955 1bf87e8456fb175163c3c6dfb2b96d98 303 SUPERFAMILY SSF51569 3 299 2.2E-57 T 06-07-2017 BWK49_RS03580 d7e18b01230e9757f6e3a9358878f20f 393 SUPERFAMILY SSF47203 232 391 2.58E-23 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS03580 d7e18b01230e9757f6e3a9358878f20f 393 Gene3D G3DSA:2.40.110.10 127 221 2.2E-34 T 06-07-2017 BWK49_RS03580 d7e18b01230e9757f6e3a9358878f20f 393 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 123 3.8E-22 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS03580 d7e18b01230e9757f6e3a9358878f20f 393 Gene3D G3DSA:1.10.540.10 4 123 4.3E-28 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS03580 d7e18b01230e9757f6e3a9358878f20f 393 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 232 386 9.7E-39 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS03580 d7e18b01230e9757f6e3a9358878f20f 393 SUPERFAMILY SSF56645 3 245 5.24E-69 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS03580 d7e18b01230e9757f6e3a9358878f20f 393 Gene3D G3DSA:1.20.140.10 222 392 2.6E-37 T 06-07-2017 BWK49_RS03580 d7e18b01230e9757f6e3a9358878f20f 393 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 128 216 1.9E-21 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 BWK49_RS28210 313fab55e8a46865d7a78f61b5132ebf 586 SUPERFAMILY SSF51556 62 320 8.16E-69 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS28210 313fab55e8a46865d7a78f61b5132ebf 586 SUPERFAMILY SSF51556 376 514 8.16E-69 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS28210 313fab55e8a46865d7a78f61b5132ebf 586 Pfam PF07969 Amidohydrolase family 50 567 3.7E-61 T 06-07-2017 IPR013108 Amidohydrolase 3 BWK49_RS28210 313fab55e8a46865d7a78f61b5132ebf 586 Gene3D G3DSA:2.30.40.10 1 71 2.5E-19 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 BWK49_RS28210 313fab55e8a46865d7a78f61b5132ebf 586 Gene3D G3DSA:3.20.20.140 72 312 2.6E-89 T 06-07-2017 BWK49_RS28210 313fab55e8a46865d7a78f61b5132ebf 586 Gene3D G3DSA:3.20.20.140 436 498 2.6E-89 T 06-07-2017 BWK49_RS28210 313fab55e8a46865d7a78f61b5132ebf 586 SUPERFAMILY SSF51338 514 579 3.09E-19 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 BWK49_RS28210 313fab55e8a46865d7a78f61b5132ebf 586 SUPERFAMILY SSF51338 1 61 3.09E-19 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 BWK49_RS28210 313fab55e8a46865d7a78f61b5132ebf 586 Gene3D G3DSA:2.30.40.10 499 582 1.4E-9 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 BWK49_RS22290 ca782c300a393ef6f270a8d730ea5697 436 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 163 181 2.0E-9 T 06-07-2017 BWK49_RS22290 ca782c300a393ef6f270a8d730ea5697 436 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 282 304 2.0E-9 T 06-07-2017 BWK49_RS22290 ca782c300a393ef6f270a8d730ea5697 436 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 103 121 2.0E-9 T 06-07-2017 BWK49_RS22290 ca782c300a393ef6f270a8d730ea5697 436 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 2.0E-9 T 06-07-2017 BWK49_RS22290 ca782c300a393ef6f270a8d730ea5697 436 Gene3D G3DSA:3.50.50.60 111 265 2.7E-16 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS22290 ca782c300a393ef6f270a8d730ea5697 436 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 297 304 1.1E-6 T 06-07-2017 BWK49_RS22290 ca782c300a393ef6f270a8d730ea5697 436 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 163 188 1.1E-6 T 06-07-2017 BWK49_RS22290 ca782c300a393ef6f270a8d730ea5697 436 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 1.1E-6 T 06-07-2017 BWK49_RS22290 ca782c300a393ef6f270a8d730ea5697 436 Gene3D G3DSA:3.50.50.60 266 337 1.5E-25 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS22290 ca782c300a393ef6f270a8d730ea5697 436 Gene3D G3DSA:3.50.50.60 3 110 1.5E-25 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS22290 ca782c300a393ef6f270a8d730ea5697 436 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 327 1.4E-46 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS22290 ca782c300a393ef6f270a8d730ea5697 436 SUPERFAMILY SSF51905 3 336 7.21E-26 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS20880 911e1785e720beae7ffd6da0f239238c 170 SUPERFAMILY SSF50475 9 148 2.24E-39 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 BWK49_RS20880 911e1785e720beae7ffd6da0f239238c 170 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 13 99 3.5E-22 T 06-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 BWK49_RS20880 911e1785e720beae7ffd6da0f239238c 170 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 17 143 5.4E-33 T 06-07-2017 IPR019920 F420-binding domain, putative BWK49_RS20880 911e1785e720beae7ffd6da0f239238c 170 Gene3D G3DSA:2.30.110.10 11 149 2.1E-40 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 BWK49_RS09895 8778ac8a80aed305defc0f90b2d339c5 396 SUPERFAMILY SSF56601 15 390 1.74E-70 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like BWK49_RS09895 8778ac8a80aed305defc0f90b2d339c5 396 Pfam PF00144 Beta-lactamase 32 381 1.1E-68 T 06-07-2017 IPR001466 Beta-lactamase-related BWK49_RS09895 8778ac8a80aed305defc0f90b2d339c5 396 Gene3D G3DSA:3.40.710.10 6 383 1.9E-76 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like BWK49_RS08445 bd50ec86cbf0bb030e5ff72f777684ee 354 Pfam PF07687 Peptidase dimerisation domain 166 264 3.1E-12 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain BWK49_RS08445 bd50ec86cbf0bb030e5ff72f777684ee 354 SUPERFAMILY SSF55031 166 267 9.12E-18 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain BWK49_RS08445 bd50ec86cbf0bb030e5ff72f777684ee 354 Pfam PF01546 Peptidase family M20/M25/M40 65 352 1.3E-19 T 06-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 BWK49_RS08445 bd50ec86cbf0bb030e5ff72f777684ee 354 Gene3D G3DSA:3.40.630.10 7 174 7.8E-43 T 06-07-2017 BWK49_RS08445 bd50ec86cbf0bb030e5ff72f777684ee 354 Gene3D G3DSA:3.40.630.10 297 352 7.8E-43 T 06-07-2017 BWK49_RS08445 bd50ec86cbf0bb030e5ff72f777684ee 354 TIGRFAM TIGR01900 dapE-gram_pos: succinyl-diaminopimelate desuccinylase 5 353 3.8E-156 T 06-07-2017 IPR010174 Succinyl-diaminopimelate desuccinylase, DapE GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 BWK49_RS08445 bd50ec86cbf0bb030e5ff72f777684ee 354 Gene3D G3DSA:3.30.70.360 175 269 1.2E-21 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain BWK49_RS08445 bd50ec86cbf0bb030e5ff72f777684ee 354 SUPERFAMILY SSF53187 274 353 9.02E-42 T 06-07-2017 BWK49_RS08445 bd50ec86cbf0bb030e5ff72f777684ee 354 SUPERFAMILY SSF53187 7 178 9.02E-42 T 06-07-2017 BWK49_RS08445 bd50ec86cbf0bb030e5ff72f777684ee 354 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 64 73 - T 06-07-2017 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 BWK49_RS23500 8083ef6967b71d708ef05209da688354 269 PRINTS PR00412 Epoxide hydrolase signature 192 208 1.3E-8 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS23500 8083ef6967b71d708ef05209da688354 269 PRINTS PR00412 Epoxide hydrolase signature 25 40 1.3E-8 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS23500 8083ef6967b71d708ef05209da688354 269 PRINTS PR00412 Epoxide hydrolase signature 70 83 1.3E-8 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS23500 8083ef6967b71d708ef05209da688354 269 PRINTS PR00412 Epoxide hydrolase signature 4 22 1.3E-8 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS23500 8083ef6967b71d708ef05209da688354 269 PRINTS PR00412 Epoxide hydrolase signature 227 249 1.3E-8 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS23500 8083ef6967b71d708ef05209da688354 269 Gene3D G3DSA:3.40.50.1820 1 251 6.1E-36 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS23500 8083ef6967b71d708ef05209da688354 269 Pfam PF12697 Alpha/beta hydrolase family 1 244 8.5E-18 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS23500 8083ef6967b71d708ef05209da688354 269 SUPERFAMILY SSF53474 1 252 1.91E-38 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS07305 26705edbcb6024f2865787cc8a8aba02 308 Gene3D G3DSA:3.20.20.100 2 78 5.2E-35 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain BWK49_RS07305 26705edbcb6024f2865787cc8a8aba02 308 Gene3D G3DSA:3.20.20.100 111 202 5.2E-35 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain BWK49_RS07305 26705edbcb6024f2865787cc8a8aba02 308 SUPERFAMILY SSF51430 2 79 1.31E-37 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain BWK49_RS07305 26705edbcb6024f2865787cc8a8aba02 308 SUPERFAMILY SSF51430 112 298 1.31E-37 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain BWK49_RS07305 26705edbcb6024f2865787cc8a8aba02 308 Pfam PF00248 Aldo/keto reductase family 6 175 6.9E-29 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain BWK49_RS14250 207413abc6be8a3ebab54131f8402e86 340 Pfam PF03631 Virulence factor BrkB 27 268 1.5E-31 T 06-07-2017 IPR017039 Virulence factor BrkB BWK49_RS27750 a7dbeca94488840d6d8f939b6203e8c0 314 Gene3D G3DSA:3.90.180.10 6 155 1.5E-36 T 06-07-2017 IPR011032 GroES-like BWK49_RS27750 a7dbeca94488840d6d8f939b6203e8c0 314 Gene3D G3DSA:3.40.50.720 156 225 3.7E-9 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS27750 a7dbeca94488840d6d8f939b6203e8c0 314 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 32 104 2.6E-6 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 BWK49_RS27750 a7dbeca94488840d6d8f939b6203e8c0 314 SMART SM00829 15 308 3.1E-13 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 BWK49_RS27750 a7dbeca94488840d6d8f939b6203e8c0 314 Pfam PF13602 Zinc-binding dehydrogenase 207 308 1.6E-11 T 06-07-2017 BWK49_RS27750 a7dbeca94488840d6d8f939b6203e8c0 314 SUPERFAMILY SSF51735 120 230 1.85E-22 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS27750 a7dbeca94488840d6d8f939b6203e8c0 314 SUPERFAMILY SSF50129 7 156 1.52E-29 T 06-07-2017 IPR011032 GroES-like BWK49_RS12135 00d80584c2006465fce5317a16abcc95 137 Gene3D G3DSA:3.10.180.10 6 116 2.1E-18 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS12135 00d80584c2006465fce5317a16abcc95 137 SUPERFAMILY SSF54593 5 119 4.68E-18 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS12135 00d80584c2006465fce5317a16abcc95 137 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 114 1.9E-9 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain BWK49_RS06085 fc27b32f391811fcf3df35a33c181db9 177 Pfam PF02627 Carboxymuconolactone decarboxylase family 38 113 1.8E-14 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 BWK49_RS06085 fc27b32f391811fcf3df35a33c181db9 177 Gene3D G3DSA:1.20.1290.10 29 168 6.1E-29 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 BWK49_RS06085 fc27b32f391811fcf3df35a33c181db9 177 SUPERFAMILY SSF69118 1 168 1.32E-32 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 BWK49_RS14690 de9da45c8cad6dd8b5374a6eee7d3f5d 376 SUPERFAMILY SSF51412 1 70 8.09E-50 T 06-07-2017 BWK49_RS14690 de9da45c8cad6dd8b5374a6eee7d3f5d 376 SUPERFAMILY SSF51412 119 366 8.09E-50 T 06-07-2017 BWK49_RS14690 de9da45c8cad6dd8b5374a6eee7d3f5d 376 Pfam PF03060 Nitronate monooxygenase 21 309 2.3E-47 T 06-07-2017 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 BWK49_RS14690 de9da45c8cad6dd8b5374a6eee7d3f5d 376 Gene3D G3DSA:3.20.20.70 1 79 4.1E-63 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 BWK49_RS14690 de9da45c8cad6dd8b5374a6eee7d3f5d 376 Gene3D G3DSA:3.20.20.70 126 353 4.1E-63 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 BWK49_RS09815 05029fa92a1a8e40a2194fdfd73309bd 156 Gene3D G3DSA:2.40.50.140 5 109 1.5E-26 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS09815 05029fa92a1a8e40a2194fdfd73309bd 156 SUPERFAMILY SSF50249 7 139 6.57E-27 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS09815 05029fa92a1a8e40a2194fdfd73309bd 156 PIRSF PIRSF002070 2 147 3.8E-29 T 06-07-2017 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 BWK49_RS09815 05029fa92a1a8e40a2194fdfd73309bd 156 Pfam PF00436 Single-strand binding protein family 7 103 4.9E-18 T 06-07-2017 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 BWK49_RS08615 d19571e2cf9188a122a3eb9ac6a334ea 399 PIRSF PIRSF000106 21 398 2.1E-71 T 06-07-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 BWK49_RS08615 d19571e2cf9188a122a3eb9ac6a334ea 399 SUPERFAMILY SSF53223 22 171 1.44E-50 T 06-07-2017 BWK49_RS08615 d19571e2cf9188a122a3eb9ac6a334ea 399 Pfam PF03949 Malic enzyme, NAD binding domain 175 389 1.2E-21 T 06-07-2017 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 BWK49_RS08615 d19571e2cf9188a122a3eb9ac6a334ea 399 ProSitePatterns PS00331 Malic enzymes signature. 169 185 - T 06-07-2017 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 BWK49_RS08615 d19571e2cf9188a122a3eb9ac6a334ea 399 Gene3D G3DSA:3.40.50.10380 26 170 4.0E-48 T 06-07-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 BWK49_RS08615 d19571e2cf9188a122a3eb9ac6a334ea 399 SMART SM01274 28 161 7.8E-72 T 06-07-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 BWK49_RS08615 d19571e2cf9188a122a3eb9ac6a334ea 399 Pfam PF00390 Malic enzyme, N-terminal domain 30 159 5.0E-25 T 06-07-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 BWK49_RS08615 d19571e2cf9188a122a3eb9ac6a334ea 399 SUPERFAMILY SSF51735 173 392 2.82E-66 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS08615 d19571e2cf9188a122a3eb9ac6a334ea 399 SMART SM00919 173 393 1.1E-106 T 06-07-2017 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 BWK49_RS08615 d19571e2cf9188a122a3eb9ac6a334ea 399 Gene3D G3DSA:3.40.50.720 171 391 1.3E-71 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS02105 921e93b48cd5acaa70e1d6515224fdad 485 SMART SM00388 258 324 5.4E-21 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 BWK49_RS02105 921e93b48cd5acaa70e1d6515224fdad 485 Pfam PF00672 HAMP domain 169 245 2.2E-14 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 BWK49_RS02105 921e93b48cd5acaa70e1d6515224fdad 485 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 367 476 2.8E-22 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS02105 921e93b48cd5acaa70e1d6515224fdad 485 SUPERFAMILY SSF47384 242 325 5.69E-20 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 BWK49_RS02105 921e93b48cd5acaa70e1d6515224fdad 485 Gene3D G3DSA:1.10.287.130 251 310 4.2E-18 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 BWK49_RS02105 921e93b48cd5acaa70e1d6515224fdad 485 SUPERFAMILY SSF55874 313 476 4.85E-39 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS02105 921e93b48cd5acaa70e1d6515224fdad 485 SMART SM00387 367 478 1.4E-37 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS02105 921e93b48cd5acaa70e1d6515224fdad 485 Pfam PF00512 His Kinase A (phospho-acceptor) domain 260 324 3.0E-19 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 BWK49_RS02105 921e93b48cd5acaa70e1d6515224fdad 485 SMART SM00304 188 250 1.9E-8 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 BWK49_RS02105 921e93b48cd5acaa70e1d6515224fdad 485 Gene3D G3DSA:3.30.565.10 311 477 1.2E-42 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS02105 921e93b48cd5acaa70e1d6515224fdad 485 PRINTS PR00344 Bacterial sensor protein C-terminal signature 404 418 3.4E-12 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 BWK49_RS02105 921e93b48cd5acaa70e1d6515224fdad 485 PRINTS PR00344 Bacterial sensor protein C-terminal signature 462 475 3.4E-12 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 BWK49_RS02105 921e93b48cd5acaa70e1d6515224fdad 485 PRINTS PR00344 Bacterial sensor protein C-terminal signature 439 457 3.4E-12 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 BWK49_RS02105 921e93b48cd5acaa70e1d6515224fdad 485 PRINTS PR00344 Bacterial sensor protein C-terminal signature 422 432 3.4E-12 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 BWK49_RS28055 9e1ae3a4922c4b1e91c4896f8450cdc8 756 Gene3D G3DSA:3.30.70.100 24 86 4.5E-19 T 06-07-2017 BWK49_RS28055 9e1ae3a4922c4b1e91c4896f8450cdc8 756 ProSitePatterns PS01047 Heavy-metal-associated domain. 28 56 - T 06-07-2017 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 BWK49_RS28055 9e1ae3a4922c4b1e91c4896f8450cdc8 756 Pfam PF00403 Heavy-metal-associated domain 27 83 1.8E-9 T 06-07-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 BWK49_RS28055 9e1ae3a4922c4b1e91c4896f8450cdc8 756 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 207 747 4.1E-154 T 06-07-2017 BWK49_RS28055 9e1ae3a4922c4b1e91c4896f8450cdc8 756 SUPERFAMILY SSF56784 442 462 9.42E-56 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS28055 9e1ae3a4922c4b1e91c4896f8450cdc8 756 SUPERFAMILY SSF56784 501 744 9.42E-56 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS28055 9e1ae3a4922c4b1e91c4896f8450cdc8 756 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 218 726 5.1E-84 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 BWK49_RS28055 9e1ae3a4922c4b1e91c4896f8450cdc8 756 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 675 700 3.6E-5 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 BWK49_RS28055 9e1ae3a4922c4b1e91c4896f8450cdc8 756 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 644 660 3.6E-5 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 BWK49_RS28055 9e1ae3a4922c4b1e91c4896f8450cdc8 756 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 446 452 - T 06-07-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 BWK49_RS28055 9e1ae3a4922c4b1e91c4896f8450cdc8 756 SUPERFAMILY SSF81665 345 438 3.14E-12 T 06-07-2017 BWK49_RS28055 9e1ae3a4922c4b1e91c4896f8450cdc8 756 SUPERFAMILY SSF81665 693 723 3.14E-12 T 06-07-2017 BWK49_RS28055 9e1ae3a4922c4b1e91c4896f8450cdc8 756 SUPERFAMILY SSF81665 213 245 3.14E-12 T 06-07-2017 BWK49_RS28055 9e1ae3a4922c4b1e91c4896f8450cdc8 756 Gene3D G3DSA:2.70.150.10 210 345 1.4E-27 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 BWK49_RS28055 9e1ae3a4922c4b1e91c4896f8450cdc8 756 Gene3D G3DSA:3.40.50.1000 416 459 2.4E-50 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS28055 9e1ae3a4922c4b1e91c4896f8450cdc8 756 Gene3D G3DSA:3.40.50.1000 572 712 2.4E-50 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS28055 9e1ae3a4922c4b1e91c4896f8450cdc8 756 SUPERFAMILY SSF55008 24 87 8.64E-14 T 06-07-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 BWK49_RS28055 9e1ae3a4922c4b1e91c4896f8450cdc8 756 Pfam PF00702 haloacid dehalogenase-like hydrolase 440 658 1.5E-42 T 06-07-2017 BWK49_RS28055 9e1ae3a4922c4b1e91c4896f8450cdc8 756 Pfam PF00122 E1-E2 ATPase 217 435 5.1E-63 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 BWK49_RS28055 9e1ae3a4922c4b1e91c4896f8450cdc8 756 Gene3D G3DSA:3.40.1110.10 460 571 4.0E-20 T 06-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 BWK49_RS28055 9e1ae3a4922c4b1e91c4896f8450cdc8 756 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 163 746 1.1E-174 T 06-07-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 BWK49_RS28055 9e1ae3a4922c4b1e91c4896f8450cdc8 756 SUPERFAMILY SSF81653 250 344 3.66E-25 T 06-07-2017 BWK49_RS28055 9e1ae3a4922c4b1e91c4896f8450cdc8 756 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 294 308 2.1E-24 T 06-07-2017 BWK49_RS28055 9e1ae3a4922c4b1e91c4896f8450cdc8 756 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 444 458 2.1E-24 T 06-07-2017 BWK49_RS28055 9e1ae3a4922c4b1e91c4896f8450cdc8 756 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 569 580 2.1E-24 T 06-07-2017 BWK49_RS28055 9e1ae3a4922c4b1e91c4896f8450cdc8 756 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 591 601 2.1E-24 T 06-07-2017 BWK49_RS28055 9e1ae3a4922c4b1e91c4896f8450cdc8 756 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 644 663 2.1E-24 T 06-07-2017 BWK49_RS28055 9e1ae3a4922c4b1e91c4896f8450cdc8 756 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 667 679 2.1E-24 T 06-07-2017 BWK49_RS19840 f47a408afe2bf1ac253c395bfe68d4c8 230 SUPERFAMILY SSF46785 11 71 4.62E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS19840 f47a408afe2bf1ac253c395bfe68d4c8 230 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 31 42 3.3E-5 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 BWK49_RS19840 f47a408afe2bf1ac253c395bfe68d4c8 230 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 42 61 3.3E-5 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 BWK49_RS19840 f47a408afe2bf1ac253c395bfe68d4c8 230 SMART SM00529 33 132 7.9E-46 T 06-07-2017 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 BWK49_RS19840 f47a408afe2bf1ac253c395bfe68d4c8 230 SMART SM00899 152 230 4.3E-11 T 06-07-2017 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 BWK49_RS19840 f47a408afe2bf1ac253c395bfe68d4c8 230 SUPERFAMILY SSF50037 156 229 5.26E-7 T 06-07-2017 IPR008988 Transcriptional repressor, C-terminal BWK49_RS19840 f47a408afe2bf1ac253c395bfe68d4c8 230 Gene3D G3DSA:1.10.10.10 10 79 2.9E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS19840 f47a408afe2bf1ac253c395bfe68d4c8 230 Gene3D G3DSA:1.10.60.10 82 146 8.4E-32 T 06-07-2017 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 BWK49_RS19840 f47a408afe2bf1ac253c395bfe68d4c8 230 Pfam PF04023 FeoA domain 152 229 7.3E-22 T 06-07-2017 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 BWK49_RS19840 f47a408afe2bf1ac253c395bfe68d4c8 230 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 72 140 1.4E-31 T 06-07-2017 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 BWK49_RS19840 f47a408afe2bf1ac253c395bfe68d4c8 230 SUPERFAMILY SSF47979 72 146 2.09E-26 T 06-07-2017 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 BWK49_RS19840 f47a408afe2bf1ac253c395bfe68d4c8 230 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 10 69 1.8E-20 T 06-07-2017 IPR022687 DTXR-type HTH domain GO:0003677 BWK49_RS15705 70338d36e62e02d927940e34feb0f063 77 Gene3D G3DSA:1.10.1470.10 9 64 3.6E-6 T 06-07-2017 IPR008462 CsbD-like BWK49_RS15705 70338d36e62e02d927940e34feb0f063 77 SUPERFAMILY SSF69047 8 64 1.2E-6 T 06-07-2017 IPR008462 CsbD-like BWK49_RS16220 3587814ba3427424ba83351c7012890b 413 Pfam PF00067 Cytochrome P450 94 271 5.3E-10 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS16220 3587814ba3427424ba83351c7012890b 413 Pfam PF00067 Cytochrome P450 285 380 1.3E-16 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS16220 3587814ba3427424ba83351c7012890b 413 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 354 363 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 BWK49_RS16220 3587814ba3427424ba83351c7012890b 413 PRINTS PR00359 B-class P450 signature 204 226 2.1E-46 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS16220 3587814ba3427424ba83351c7012890b 413 PRINTS PR00359 B-class P450 signature 352 361 2.1E-46 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS16220 3587814ba3427424ba83351c7012890b 413 PRINTS PR00359 B-class P450 signature 330 345 2.1E-46 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS16220 3587814ba3427424ba83351c7012890b 413 PRINTS PR00359 B-class P450 signature 162 177 2.1E-46 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS16220 3587814ba3427424ba83351c7012890b 413 PRINTS PR00359 B-class P450 signature 285 296 2.1E-46 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS16220 3587814ba3427424ba83351c7012890b 413 PRINTS PR00359 B-class P450 signature 361 372 2.1E-46 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS16220 3587814ba3427424ba83351c7012890b 413 PRINTS PR00359 B-class P450 signature 99 110 2.1E-46 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS16220 3587814ba3427424ba83351c7012890b 413 PRINTS PR00359 B-class P450 signature 145 161 2.1E-46 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS16220 3587814ba3427424ba83351c7012890b 413 PRINTS PR00359 B-class P450 signature 302 329 2.1E-46 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS16220 3587814ba3427424ba83351c7012890b 413 SUPERFAMILY SSF48264 32 409 7.99E-86 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS16220 3587814ba3427424ba83351c7012890b 413 PRINTS PR00385 P450 superfamily signature 361 372 6.0E-7 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS16220 3587814ba3427424ba83351c7012890b 413 PRINTS PR00385 P450 superfamily signature 352 361 6.0E-7 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS16220 3587814ba3427424ba83351c7012890b 413 PRINTS PR00385 P450 superfamily signature 250 267 6.0E-7 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS16220 3587814ba3427424ba83351c7012890b 413 PRINTS PR00385 P450 superfamily signature 285 296 6.0E-7 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS16220 3587814ba3427424ba83351c7012890b 413 Gene3D G3DSA:1.10.630.10 30 410 7.9E-104 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS02325 56c865ebfc2e48cffc2efe1f43732643 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 86 97 8.0E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS02325 56c865ebfc2e48cffc2efe1f43732643 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 8.0E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS02325 56c865ebfc2e48cffc2efe1f43732643 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 148 8.0E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS02325 56c865ebfc2e48cffc2efe1f43732643 257 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 147 175 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS02325 56c865ebfc2e48cffc2efe1f43732643 257 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 253 6.1E-52 T 06-07-2017 BWK49_RS02325 56c865ebfc2e48cffc2efe1f43732643 257 Gene3D G3DSA:3.40.50.720 7 253 1.2E-68 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS02325 56c865ebfc2e48cffc2efe1f43732643 257 SUPERFAMILY SSF51735 11 253 1.15E-64 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS02325 56c865ebfc2e48cffc2efe1f43732643 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 1.0E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS02325 56c865ebfc2e48cffc2efe1f43732643 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 1.0E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS02325 56c865ebfc2e48cffc2efe1f43732643 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 1.0E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS02325 56c865ebfc2e48cffc2efe1f43732643 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 1.0E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS02325 56c865ebfc2e48cffc2efe1f43732643 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 1.0E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27990 a95db7270c99376ff8e09cb9b8b6c353 197 SUPERFAMILY SSF48498 77 196 8.26E-20 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS27990 a95db7270c99376ff8e09cb9b8b6c353 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 3.1E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS27990 a95db7270c99376ff8e09cb9b8b6c353 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 3.1E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS27990 a95db7270c99376ff8e09cb9b8b6c353 197 Gene3D G3DSA:1.10.10.60 8 56 1.3E-21 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS27990 a95db7270c99376ff8e09cb9b8b6c353 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 64 6.9E-14 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS27990 a95db7270c99376ff8e09cb9b8b6c353 197 Pfam PF16859 Bacterial transcriptional repressor C-terminal 76 175 1.7E-17 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS27990 a95db7270c99376ff8e09cb9b8b6c353 197 SUPERFAMILY SSF46689 8 71 5.99E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS27990 a95db7270c99376ff8e09cb9b8b6c353 197 Gene3D G3DSA:1.10.357.10 57 195 4.3E-22 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS13115 6fe3ae69d70717d59057264fe8e583f6 258 Gene3D G3DSA:3.20.20.10 10 254 3.1E-72 T 06-07-2017 IPR029066 PLP-binding barrel BWK49_RS13115 6fe3ae69d70717d59057264fe8e583f6 258 ProSitePatterns PS01211 Uncharacterized protein family UPF0001 signature. 97 111 - T 06-07-2017 IPR011078 Uncharacterised protein family UPF0001 BWK49_RS13115 6fe3ae69d70717d59057264fe8e583f6 258 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 16 253 6.7E-34 T 06-07-2017 IPR011078 Uncharacterised protein family UPF0001 BWK49_RS13115 6fe3ae69d70717d59057264fe8e583f6 258 PIRSF PIRSF004848 9 258 5.6E-65 T 06-07-2017 IPR011078 Uncharacterised protein family UPF0001 BWK49_RS13115 6fe3ae69d70717d59057264fe8e583f6 258 Pfam PF01168 Alanine racemase, N-terminal domain 19 252 1.4E-11 T 06-07-2017 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 BWK49_RS13115 6fe3ae69d70717d59057264fe8e583f6 258 SUPERFAMILY SSF51419 12 251 5.67E-58 T 06-07-2017 IPR029066 PLP-binding barrel BWK49_RS21265 26ce5795bed98279171d10cd0cdf02c2 276 SUPERFAMILY SSF55811 148 209 1.44E-15 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 BWK49_RS21265 26ce5795bed98279171d10cd0cdf02c2 276 SUPERFAMILY SSF55811 8 60 1.44E-15 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 BWK49_RS21265 26ce5795bed98279171d10cd0cdf02c2 276 SUPERFAMILY SSF55811 88 99 1.44E-15 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 BWK49_RS21265 26ce5795bed98279171d10cd0cdf02c2 276 Gene3D G3DSA:3.90.79.10 7 99 3.8E-16 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 BWK49_RS21265 26ce5795bed98279171d10cd0cdf02c2 276 Gene3D G3DSA:3.90.79.10 148 204 3.8E-16 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 BWK49_RS19500 3210dfe10e5493081d67036097b80740 161 SUPERFAMILY SSF50814 4 160 6.32E-49 T 06-07-2017 IPR011038 Calycin-like BWK49_RS19500 3210dfe10e5493081d67036097b80740 161 Hamap MF_01297 UPF0678 fatty acid-binding protein-like protein . 1 161 27.714 T 06-07-2017 IPR022939 Uncharacterised protein family UPF0678 BWK49_RS19500 3210dfe10e5493081d67036097b80740 161 Pfam PF08768 Domain of unknown function (DUF1794) 9 159 2.1E-43 T 06-07-2017 IPR014878 Domain of unknown function DUF1794 BWK49_RS14130 e76fd267cf441874110001055d8730ac 324 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 279 301 2.4E-7 T 06-07-2017 IPR022171 PPE family, C-terminal BWK49_RS14130 e76fd267cf441874110001055d8730ac 324 SUPERFAMILY SSF140459 6 171 3.92E-45 T 06-07-2017 BWK49_RS14130 e76fd267cf441874110001055d8730ac 324 Pfam PF00823 PPE family 6 160 3.3E-45 T 06-07-2017 IPR000030 PPE family BWK49_RS25805 37fa2c30abe58659ba43c93dd1083267 299 Pfam PF04072 Leucine carboxyl methyltransferase 19 203 2.1E-63 T 06-07-2017 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 BWK49_RS25805 37fa2c30abe58659ba43c93dd1083267 299 SUPERFAMILY SSF53335 15 291 3.74E-75 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS25805 37fa2c30abe58659ba43c93dd1083267 299 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 17 278 2.0E-77 T 06-07-2017 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 BWK49_RS25805 37fa2c30abe58659ba43c93dd1083267 299 Gene3D G3DSA:3.40.50.150 16 219 7.0E-20 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS22550 d73a22f96ae03b77bec2e5fdc834f173 346 PIRSF PIRSF005739 1 344 2.1E-51 T 06-07-2017 IPR016461 O-methyltransferase COMT-type GO:0008168 BWK49_RS22550 d73a22f96ae03b77bec2e5fdc834f173 346 Gene3D G3DSA:3.40.50.150 104 344 3.3E-65 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS22550 d73a22f96ae03b77bec2e5fdc834f173 346 Pfam PF00891 O-methyltransferase 118 331 4.0E-48 T 06-07-2017 IPR001077 O-methyltransferase, family 2 GO:0008171 BWK49_RS22550 d73a22f96ae03b77bec2e5fdc834f173 346 SUPERFAMILY SSF53335 102 341 3.0E-47 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS22550 d73a22f96ae03b77bec2e5fdc834f173 346 SUPERFAMILY SSF46785 19 99 6.1E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS22550 d73a22f96ae03b77bec2e5fdc834f173 346 Gene3D G3DSA:1.10.10.10 16 103 5.7E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS16950 13f145307b72a02db8e2b5dc7960d155 164 Hamap MF_00173 Arginine repressor [argR]. 1 164 60.331 T 06-07-2017 IPR001669 Arginine repressor GO:0003700|GO:0006355 BWK49_RS16950 13f145307b72a02db8e2b5dc7960d155 164 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 103 161 8.0E-19 T 06-07-2017 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 BWK49_RS16950 13f145307b72a02db8e2b5dc7960d155 164 Pfam PF02863 Arginine repressor, C-terminal domain 96 161 2.3E-23 T 06-07-2017 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 BWK49_RS16950 13f145307b72a02db8e2b5dc7960d155 164 Gene3D G3DSA:3.30.1360.40 89 163 5.5E-27 T 06-07-2017 IPR024946 Arginine repressor C-terminal-like domain BWK49_RS16950 13f145307b72a02db8e2b5dc7960d155 164 TIGRFAM TIGR01529 argR_whole: arginine repressor 14 163 3.6E-46 T 06-07-2017 IPR001669 Arginine repressor GO:0003700|GO:0006355 BWK49_RS16950 13f145307b72a02db8e2b5dc7960d155 164 Pfam PF01316 Arginine repressor, DNA binding domain 11 79 1.2E-24 T 06-07-2017 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 BWK49_RS16950 13f145307b72a02db8e2b5dc7960d155 164 Gene3D G3DSA:1.10.10.10 10 80 1.2E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS16950 13f145307b72a02db8e2b5dc7960d155 164 SUPERFAMILY SSF55252 95 161 4.45E-17 T 06-07-2017 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 BWK49_RS16950 13f145307b72a02db8e2b5dc7960d155 164 PRINTS PR01467 Bacterial arginine repressor signature 46 61 1.0E-26 T 06-07-2017 IPR001669 Arginine repressor GO:0003700|GO:0006355 BWK49_RS16950 13f145307b72a02db8e2b5dc7960d155 164 PRINTS PR01467 Bacterial arginine repressor signature 103 116 1.0E-26 T 06-07-2017 IPR001669 Arginine repressor GO:0003700|GO:0006355 BWK49_RS16950 13f145307b72a02db8e2b5dc7960d155 164 PRINTS PR01467 Bacterial arginine repressor signature 30 43 1.0E-26 T 06-07-2017 IPR001669 Arginine repressor GO:0003700|GO:0006355 BWK49_RS16950 13f145307b72a02db8e2b5dc7960d155 164 PRINTS PR01467 Bacterial arginine repressor signature 133 148 1.0E-26 T 06-07-2017 IPR001669 Arginine repressor GO:0003700|GO:0006355 BWK49_RS16950 13f145307b72a02db8e2b5dc7960d155 164 SUPERFAMILY SSF46785 11 79 6.22E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS05955 ba612c88e9b78c5eb7a5f450a0bb4c97 933 SMART SM00421 867 924 4.6E-21 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS05955 ba612c88e9b78c5eb7a5f450a0bb4c97 933 Gene3D G3DSA:3.40.50.300 8 160 8.7E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS05955 ba612c88e9b78c5eb7a5f450a0bb4c97 933 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 884 900 3.1E-9 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS05955 ba612c88e9b78c5eb7a5f450a0bb4c97 933 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 870 884 3.1E-9 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS05955 ba612c88e9b78c5eb7a5f450a0bb4c97 933 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 900 912 3.1E-9 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS05955 ba612c88e9b78c5eb7a5f450a0bb4c97 933 SUPERFAMILY SSF52540 123 223 2.49E-7 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS05955 ba612c88e9b78c5eb7a5f450a0bb4c97 933 SUPERFAMILY SSF52540 10 57 2.49E-7 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS05955 ba612c88e9b78c5eb7a5f450a0bb4c97 933 Pfam PF00196 Bacterial regulatory proteins, luxR family 870 920 2.9E-14 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS05955 ba612c88e9b78c5eb7a5f450a0bb4c97 933 SUPERFAMILY SSF46894 869 929 1.56E-16 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 BWK49_RS05955 ba612c88e9b78c5eb7a5f450a0bb4c97 933 Gene3D G3DSA:1.10.10.10 869 926 2.5E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS05955 ba612c88e9b78c5eb7a5f450a0bb4c97 933 Pfam PF13191 AAA ATPase domain 1 151 2.5E-18 T 06-07-2017 BWK49_RS02250 c55d76a0aa79799ee76b5d19fe68ee76 423 Pfam PF13469 Sulfotransferase family 121 369 6.9E-37 T 06-07-2017 BWK49_RS02250 c55d76a0aa79799ee76b5d19fe68ee76 423 Gene3D G3DSA:3.40.50.300 255 320 2.0E-7 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS02250 c55d76a0aa79799ee76b5d19fe68ee76 423 Gene3D G3DSA:3.40.50.300 119 179 2.0E-7 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS02250 c55d76a0aa79799ee76b5d19fe68ee76 423 SUPERFAMILY SSF52540 92 169 4.91E-28 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS02250 c55d76a0aa79799ee76b5d19fe68ee76 423 SUPERFAMILY SSF52540 245 399 4.91E-28 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS28930 133fce99be63478fedeb8f3ca0f1588b 193 SUPERFAMILY SSF53041 52 182 8.5E-23 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 BWK49_RS28930 133fce99be63478fedeb8f3ca0f1588b 193 SMART SM00857 52 187 2.3E-22 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 BWK49_RS28930 133fce99be63478fedeb8f3ca0f1588b 193 ProSitePatterns PS00397 Site-specific recombinases active site. 55 63 - T 06-07-2017 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 BWK49_RS28930 133fce99be63478fedeb8f3ca0f1588b 193 Gene3D G3DSA:3.40.50.1390 52 168 5.7E-18 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 BWK49_RS28930 133fce99be63478fedeb8f3ca0f1588b 193 Pfam PF00239 Resolvase, N terminal domain 52 188 1.6E-20 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 BWK49_RS17820 0dd29074757d9016013071309cd0f2e3 494 SMART SM00388 269 337 2.3E-13 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 BWK49_RS17820 0dd29074757d9016013071309cd0f2e3 494 PRINTS PR00344 Bacterial sensor protein C-terminal signature 451 469 1.2E-12 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 BWK49_RS17820 0dd29074757d9016013071309cd0f2e3 494 PRINTS PR00344 Bacterial sensor protein C-terminal signature 434 444 1.2E-12 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 BWK49_RS17820 0dd29074757d9016013071309cd0f2e3 494 PRINTS PR00344 Bacterial sensor protein C-terminal signature 416 430 1.2E-12 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 BWK49_RS17820 0dd29074757d9016013071309cd0f2e3 494 PRINTS PR00344 Bacterial sensor protein C-terminal signature 474 487 1.2E-12 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 BWK49_RS17820 0dd29074757d9016013071309cd0f2e3 494 SUPERFAMILY SSF47384 256 337 1.14E-16 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 BWK49_RS17820 0dd29074757d9016013071309cd0f2e3 494 Gene3D G3DSA:1.10.287.130 261 324 4.0E-13 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 BWK49_RS17820 0dd29074757d9016013071309cd0f2e3 494 Pfam PF00672 HAMP domain 182 250 4.1E-11 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 BWK49_RS17820 0dd29074757d9016013071309cd0f2e3 494 Gene3D G3DSA:3.30.565.10 325 490 5.0E-41 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS17820 0dd29074757d9016013071309cd0f2e3 494 Pfam PF00512 His Kinase A (phospho-acceptor) domain 271 337 3.0E-13 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 BWK49_RS17820 0dd29074757d9016013071309cd0f2e3 494 SMART SM00304 201 254 1.3E-7 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 BWK49_RS17820 0dd29074757d9016013071309cd0f2e3 494 SUPERFAMILY SSF158472 202 251 1.26E-5 T 06-07-2017 BWK49_RS17820 0dd29074757d9016013071309cd0f2e3 494 SUPERFAMILY SSF55874 326 488 2.62E-40 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS17820 0dd29074757d9016013071309cd0f2e3 494 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 380 488 3.6E-21 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS17820 0dd29074757d9016013071309cd0f2e3 494 SMART SM00387 379 490 1.4E-38 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS13060 297288be967ca6ae9a88ba9cd315de70 185 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 49 6.6E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS13060 297288be967ca6ae9a88ba9cd315de70 185 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 5 18 6.6E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS13060 297288be967ca6ae9a88ba9cd315de70 185 SUPERFAMILY SSF48498 64 181 1.24E-15 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS13060 297288be967ca6ae9a88ba9cd315de70 185 Gene3D G3DSA:1.10.357.10 48 179 1.6E-19 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS13060 297288be967ca6ae9a88ba9cd315de70 185 Pfam PF16859 Bacterial transcriptional repressor C-terminal 64 174 1.4E-23 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS13060 297288be967ca6ae9a88ba9cd315de70 185 Gene3D G3DSA:1.10.10.60 2 47 4.0E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS13060 297288be967ca6ae9a88ba9cd315de70 185 Pfam PF00440 Bacterial regulatory proteins, tetR family 5 51 1.6E-14 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS13060 297288be967ca6ae9a88ba9cd315de70 185 SUPERFAMILY SSF46689 3 56 5.34E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS00385 f8c63abf18052434763a434eefc49a28 84 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 3 82 20.408 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS00385 f8c63abf18052434763a434eefc49a28 84 ProSitePatterns PS00057 Ribosomal protein S18 signature. 30 53 - T 06-07-2017 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS00385 f8c63abf18052434763a434eefc49a28 84 Gene3D G3DSA:4.10.640.10 18 81 1.2E-29 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS00385 f8c63abf18052434763a434eefc49a28 84 PRINTS PR00974 Ribosomal protein S18 family signature 37 47 1.6E-16 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS00385 f8c63abf18052434763a434eefc49a28 84 PRINTS PR00974 Ribosomal protein S18 family signature 69 79 1.6E-16 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS00385 f8c63abf18052434763a434eefc49a28 84 PRINTS PR00974 Ribosomal protein S18 family signature 47 54 1.6E-16 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS00385 f8c63abf18052434763a434eefc49a28 84 PRINTS PR00974 Ribosomal protein S18 family signature 55 69 1.6E-16 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS00385 f8c63abf18052434763a434eefc49a28 84 Pfam PF01084 Ribosomal protein S18 28 77 1.8E-22 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS00385 f8c63abf18052434763a434eefc49a28 84 TIGRFAM TIGR00165 S18: ribosomal protein bS18 17 81 3.7E-27 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS00385 f8c63abf18052434763a434eefc49a28 84 SUPERFAMILY SSF46911 10 81 1.09E-25 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS00385 f8c63abf18052434763a434eefc49a28 84 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 30 81 4.0E-24 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS10150 10fb893a5d7eefdc564928c2096bf587 285 Pfam PF10531 SLBB domain 127 180 5.8E-7 T 06-07-2017 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS10150 10fb893a5d7eefdc564928c2096bf587 285 Gene3D G3DSA:1.10.150.320 219 285 1.2E-19 T 06-07-2017 BWK49_RS10150 10fb893a5d7eefdc564928c2096bf587 285 SMART SM00278 263 282 5.8 T 06-07-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 BWK49_RS10150 10fb893a5d7eefdc564928c2096bf587 285 SMART SM00278 233 252 0.048 T 06-07-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 BWK49_RS10150 10fb893a5d7eefdc564928c2096bf587 285 Pfam PF12836 Helix-hairpin-helix motif 222 284 3.4E-22 T 06-07-2017 BWK49_RS10150 10fb893a5d7eefdc564928c2096bf587 285 TIGRFAM TIGR00426 TIGR00426: competence protein ComEA helix-hairpin-helix repeat region 222 283 1.3E-17 T 06-07-2017 IPR004509 Competence protein ComEA, helix-hairpin-helix domain BWK49_RS10150 10fb893a5d7eefdc564928c2096bf587 285 Gene3D G3DSA:3.10.560.10 124 182 4.4E-6 T 06-07-2017 BWK49_RS10150 10fb893a5d7eefdc564928c2096bf587 285 SUPERFAMILY SSF47781 212 282 5.0E-27 T 06-07-2017 IPR010994 RuvA domain 2-like BWK49_RS22645 6ad5c936a643b5ec0c24f28b71244b99 1115 Pfam PF00580 UvrD/REP helicase N-terminal domain 20 335 2.4E-39 T 06-07-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 BWK49_RS22645 6ad5c936a643b5ec0c24f28b71244b99 1115 Gene3D G3DSA:3.40.50.300 668 703 1.5E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS22645 6ad5c936a643b5ec0c24f28b71244b99 1115 Gene3D G3DSA:3.40.50.300 754 802 1.5E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS22645 6ad5c936a643b5ec0c24f28b71244b99 1115 Gene3D G3DSA:3.40.50.300 350 465 1.5E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS22645 6ad5c936a643b5ec0c24f28b71244b99 1115 Pfam PF12705 PD-(D/E)XK nuclease superfamily 904 1071 1.5E-11 T 06-07-2017 BWK49_RS22645 6ad5c936a643b5ec0c24f28b71244b99 1115 SUPERFAMILY SSF52540 758 803 1.21E-107 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS22645 6ad5c936a643b5ec0c24f28b71244b99 1115 SUPERFAMILY SSF52540 669 705 1.21E-107 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS22645 6ad5c936a643b5ec0c24f28b71244b99 1115 SUPERFAMILY SSF52540 16 190 1.21E-107 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS22645 6ad5c936a643b5ec0c24f28b71244b99 1115 SUPERFAMILY SSF52540 223 501 1.21E-107 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS22645 6ad5c936a643b5ec0c24f28b71244b99 1115 SUPERFAMILY SSF52540 541 637 1.21E-107 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS22645 6ad5c936a643b5ec0c24f28b71244b99 1115 SUPERFAMILY SSF52980 936 1053 1.13E-5 T 06-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 BWK49_RS22645 6ad5c936a643b5ec0c24f28b71244b99 1115 Gene3D G3DSA:1.10.486.10 466 627 7.2E-20 T 06-07-2017 BWK49_RS22645 6ad5c936a643b5ec0c24f28b71244b99 1115 Gene3D G3DSA:3.40.50.300 18 173 1.1E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS22645 6ad5c936a643b5ec0c24f28b71244b99 1115 Gene3D G3DSA:3.40.50.300 233 337 1.1E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS22645 6ad5c936a643b5ec0c24f28b71244b99 1115 Pfam PF13361 UvrD-like helicase C-terminal domain 353 507 1.0E-9 T 06-07-2017 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 BWK49_RS22645 6ad5c936a643b5ec0c24f28b71244b99 1115 Pfam PF13361 UvrD-like helicase C-terminal domain 668 780 3.0E-18 T 06-07-2017 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 BWK49_RS14305 0ad1e32a2edda8b4731a8e738c37c4de 281 SUPERFAMILY SSF50800 14 60 9.1E-14 T 06-07-2017 IPR011037 Pyruvate kinase-like, insert domain BWK49_RS14305 0ad1e32a2edda8b4731a8e738c37c4de 281 SUPERFAMILY SSF50800 163 277 9.1E-14 T 06-07-2017 IPR011037 Pyruvate kinase-like, insert domain BWK49_RS14305 0ad1e32a2edda8b4731a8e738c37c4de 281 Pfam PF03473 MOSC domain 157 277 2.1E-12 T 06-07-2017 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 BWK49_RS14305 0ad1e32a2edda8b4731a8e738c37c4de 281 Pfam PF03476 MOSC N-terminal beta barrel domain 15 95 1.7E-9 T 06-07-2017 IPR005303 MOSC, N-terminal beta barrel BWK49_RS17175 35796ec030fd663e1a39f029b5929bcc 194 SUPERFAMILY SSF48498 77 175 5.11E-6 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS17175 35796ec030fd663e1a39f029b5929bcc 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 10 55 6.4E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS17175 35796ec030fd663e1a39f029b5929bcc 194 Gene3D G3DSA:1.10.357.10 3 175 2.2E-25 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS17175 35796ec030fd663e1a39f029b5929bcc 194 SUPERFAMILY SSF46689 3 80 1.95E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS28100 2b6869c7a1f54096def29b9f1caed01f 216 Pfam PF10400 Virulence activator alpha C-term 105 174 3.6E-5 T 06-07-2017 IPR018309 Transcription regulator PadR, C-terminal BWK49_RS28100 2b6869c7a1f54096def29b9f1caed01f 216 Gene3D G3DSA:1.10.10.10 12 96 1.8E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS28100 2b6869c7a1f54096def29b9f1caed01f 216 SUPERFAMILY SSF46785 12 189 3.64E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS11155 af0f2ea6138531ba33333c4e2c4ebe86 398 SUPERFAMILY SSF48264 18 392 2.23E-82 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS11155 af0f2ea6138531ba33333c4e2c4ebe86 398 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 339 348 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 BWK49_RS11155 af0f2ea6138531ba33333c4e2c4ebe86 398 Gene3D G3DSA:1.10.630.10 14 393 2.8E-103 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS11155 af0f2ea6138531ba33333c4e2c4ebe86 398 PRINTS PR00359 B-class P450 signature 184 206 2.7E-29 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS11155 af0f2ea6138531ba33333c4e2c4ebe86 398 PRINTS PR00359 B-class P450 signature 270 281 2.7E-29 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS11155 af0f2ea6138531ba33333c4e2c4ebe86 398 PRINTS PR00359 B-class P450 signature 346 357 2.7E-29 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS11155 af0f2ea6138531ba33333c4e2c4ebe86 398 PRINTS PR00359 B-class P450 signature 337 346 2.7E-29 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS11155 af0f2ea6138531ba33333c4e2c4ebe86 398 PRINTS PR00359 B-class P450 signature 90 101 2.7E-29 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS11155 af0f2ea6138531ba33333c4e2c4ebe86 398 PRINTS PR00359 B-class P450 signature 136 152 2.7E-29 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS11155 af0f2ea6138531ba33333c4e2c4ebe86 398 PRINTS PR00359 B-class P450 signature 287 314 2.7E-29 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS11155 af0f2ea6138531ba33333c4e2c4ebe86 398 Pfam PF00067 Cytochrome P450 197 367 5.5E-21 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS11155 af0f2ea6138531ba33333c4e2c4ebe86 398 PRINTS PR00385 P450 superfamily signature 346 357 8.1E-7 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS11155 af0f2ea6138531ba33333c4e2c4ebe86 398 PRINTS PR00385 P450 superfamily signature 337 346 8.1E-7 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS11155 af0f2ea6138531ba33333c4e2c4ebe86 398 PRINTS PR00385 P450 superfamily signature 270 281 8.1E-7 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS11155 af0f2ea6138531ba33333c4e2c4ebe86 398 PRINTS PR00385 P450 superfamily signature 235 252 8.1E-7 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS05465 4ac00e2b81734eef2e62b1450d81d2d1 542 Gene3D G3DSA:3.40.50.980 189 342 6.3E-36 T 06-07-2017 BWK49_RS05465 4ac00e2b81734eef2e62b1450d81d2d1 542 SUPERFAMILY SSF56801 14 533 9.94E-134 T 06-07-2017 BWK49_RS05465 4ac00e2b81734eef2e62b1450d81d2d1 542 Gene3D G3DSA:2.30.38.10 357 431 4.7E-19 T 06-07-2017 BWK49_RS05465 4ac00e2b81734eef2e62b1450d81d2d1 542 Gene3D G3DSA:3.30.300.30 434 532 4.6E-30 T 06-07-2017 BWK49_RS05465 4ac00e2b81734eef2e62b1450d81d2d1 542 Gene3D G3DSA:3.40.50.980 19 188 9.7E-26 T 06-07-2017 BWK49_RS05465 4ac00e2b81734eef2e62b1450d81d2d1 542 ProSitePatterns PS00455 Putative AMP-binding domain signature. 182 193 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS05465 4ac00e2b81734eef2e62b1450d81d2d1 542 Pfam PF00501 AMP-binding enzyme 23 437 4.7E-88 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS05465 4ac00e2b81734eef2e62b1450d81d2d1 542 Pfam PF13193 AMP-binding enzyme C-terminal domain 446 521 1.5E-17 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS01640 459372b1f5b3044e509156f30adfdcb8 410 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 144 207 3.0E-6 T 06-07-2017 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 BWK49_RS01640 459372b1f5b3044e509156f30adfdcb8 410 Gene3D G3DSA:3.30.360.10 148 260 6.7E-21 T 06-07-2017 BWK49_RS01640 459372b1f5b3044e509156f30adfdcb8 410 Gene3D G3DSA:3.30.360.10 351 404 6.7E-21 T 06-07-2017 BWK49_RS01640 459372b1f5b3044e509156f30adfdcb8 410 SUPERFAMILY SSF51735 10 159 1.43E-42 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS01640 459372b1f5b3044e509156f30adfdcb8 410 Gene3D G3DSA:3.40.50.720 7 147 2.4E-41 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS01640 459372b1f5b3044e509156f30adfdcb8 410 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 12 130 7.2E-26 T 06-07-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 BWK49_RS01640 459372b1f5b3044e509156f30adfdcb8 410 SUPERFAMILY SSF55347 138 263 1.26E-13 T 06-07-2017 BWK49_RS17565 5e2b681fb25137ebea2a98e182536c47 200 ProSitePatterns PS00855 Signal peptidases II signature. 123 135 - T 06-07-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 BWK49_RS17565 5e2b681fb25137ebea2a98e182536c47 200 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 120 135 1.2E-16 T 06-07-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 BWK49_RS17565 5e2b681fb25137ebea2a98e182536c47 200 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 158 174 1.2E-16 T 06-07-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 BWK49_RS17565 5e2b681fb25137ebea2a98e182536c47 200 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 78 86 1.2E-16 T 06-07-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 BWK49_RS17565 5e2b681fb25137ebea2a98e182536c47 200 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 31 183 15.513 T 06-07-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 BWK49_RS17565 5e2b681fb25137ebea2a98e182536c47 200 Pfam PF01252 Signal peptidase (SPase) II 40 178 2.4E-30 T 06-07-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 BWK49_RS17565 5e2b681fb25137ebea2a98e182536c47 200 TIGRFAM TIGR00077 lspA: signal peptidase II 35 178 2.4E-27 T 06-07-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 BWK49_RS22570 346f43e92f23a59970ef6f33e702422e 299 Pfam PF00106 short chain dehydrogenase 5 196 4.0E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS22570 346f43e92f23a59970ef6f33e702422e 299 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 1.7E-15 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS22570 346f43e92f23a59970ef6f33e702422e 299 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 1.7E-15 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS22570 346f43e92f23a59970ef6f33e702422e 299 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 1.7E-15 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS22570 346f43e92f23a59970ef6f33e702422e 299 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 1.7E-15 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS22570 346f43e92f23a59970ef6f33e702422e 299 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 1.7E-15 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS22570 346f43e92f23a59970ef6f33e702422e 299 Gene3D G3DSA:3.40.50.720 5 247 1.4E-47 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS22570 346f43e92f23a59970ef6f33e702422e 299 SUPERFAMILY SSF51735 3 240 1.83E-46 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS25255 c727437ab57e4c3711fa85c5f004b9e0 552 SUPERFAMILY SSF69618 282 533 5.89E-69 T 06-07-2017 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 BWK49_RS25255 c727437ab57e4c3711fa85c5f004b9e0 552 Gene3D G3DSA:3.40.1010.10 99 151 5.2E-31 T 06-07-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 BWK49_RS25255 c727437ab57e4c3711fa85c5f004b9e0 552 Gene3D G3DSA:3.40.1010.10 10 66 5.2E-31 T 06-07-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 BWK49_RS25255 c727437ab57e4c3711fa85c5f004b9e0 552 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 12 237 4.9E-41 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 BWK49_RS25255 c727437ab57e4c3711fa85c5f004b9e0 552 Gene3D G3DSA:3.40.50.10090 417 533 7.9E-35 T 06-07-2017 BWK49_RS25255 c727437ab57e4c3711fa85c5f004b9e0 552 Gene3D G3DSA:3.40.50.10090 280 409 3.3E-38 T 06-07-2017 BWK49_RS25255 c727437ab57e4c3711fa85c5f004b9e0 552 Gene3D G3DSA:3.30.950.10 156 279 6.6E-27 T 06-07-2017 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 BWK49_RS25255 c727437ab57e4c3711fa85c5f004b9e0 552 SUPERFAMILY SSF53790 94 285 3.01E-41 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 BWK49_RS25255 c727437ab57e4c3711fa85c5f004b9e0 552 SUPERFAMILY SSF53790 7 67 3.01E-41 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 BWK49_RS25255 c727437ab57e4c3711fa85c5f004b9e0 552 Pfam PF02602 Uroporphyrinogen-III synthase HemD 296 526 7.3E-63 T 06-07-2017 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 BWK49_RS12740 d65aec4e6a5398b053cf2897afaaa876 60 Gene3D G3DSA:1.10.10.10 9 56 5.1E-9 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS12740 d65aec4e6a5398b053cf2897afaaa876 60 Pfam PF12728 Helix-turn-helix domain 1 50 8.7E-9 T 06-07-2017 BWK49_RS12740 d65aec4e6a5398b053cf2897afaaa876 60 SUPERFAMILY SSF46955 2 51 6.87E-10 T 06-07-2017 IPR009061 Putative DNA-binding domain BWK49_RS02200 b4343c0ad6044e1b08db4c3466172c8a 152 SUPERFAMILY SSF53927 4 150 1.39E-44 T 06-07-2017 IPR016193 Cytidine deaminase-like GO:0003824 BWK49_RS02200 b4343c0ad6044e1b08db4c3466172c8a 152 Gene3D G3DSA:3.40.140.10 4 148 3.3E-51 T 06-07-2017 BWK49_RS02200 b4343c0ad6044e1b08db4c3466172c8a 152 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 53 91 - T 06-07-2017 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 BWK49_RS02200 b4343c0ad6044e1b08db4c3466172c8a 152 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 4 102 2.6E-23 T 06-07-2017 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 BWK49_RS02200 b4343c0ad6044e1b08db4c3466172c8a 152 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 8 150 44.564 T 06-07-2017 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 BWK49_RS17730 22e79decd6f135d9f794d317def41977 268 Pfam PF05711 Macrocin-O-methyltransferase (TylF) 11 267 9.4E-111 T 06-07-2017 IPR008884 Macrocin-O-methyltransferase BWK49_RS17730 22e79decd6f135d9f794d317def41977 268 Gene3D G3DSA:3.40.50.150 162 232 2.3E-5 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS17730 22e79decd6f135d9f794d317def41977 268 SUPERFAMILY SSF53335 173 234 7.31E-12 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS17730 22e79decd6f135d9f794d317def41977 268 SUPERFAMILY SSF53335 82 135 7.31E-12 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS25720 8a8302666d55edb1a29804448724ca0e 227 SUPERFAMILY SSF49329 59 225 9.29E-43 T 06-07-2017 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 BWK49_RS25720 8a8302666d55edb1a29804448724ca0e 227 Gene3D G3DSA:2.60.40.200 60 225 9.3E-45 T 06-07-2017 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 BWK49_RS25720 8a8302666d55edb1a29804448724ca0e 227 Pfam PF00080 Copper/zinc superoxide dismutase (SODC) 68 224 8.3E-29 T 06-07-2017 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 BWK49_RS25720 8a8302666d55edb1a29804448724ca0e 227 ProSitePatterns PS00332 Copper/Zinc superoxide dismutase signature 2. 213 224 - T 06-07-2017 IPR018152 Superoxide dismutase, copper/zinc, binding site GO:0004784|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 BWK49_RS02490 cb0c8bfa3ef006220fec14b456e47406 114 SUPERFAMILY SSF82607 12 104 1.31E-30 T 06-07-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family BWK49_RS02490 cb0c8bfa3ef006220fec14b456e47406 114 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 5 99 21.737 T 06-07-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family BWK49_RS02490 cb0c8bfa3ef006220fec14b456e47406 114 Gene3D G3DSA:3.30.1310.10 3 105 8.0E-39 T 06-07-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family BWK49_RS02490 cb0c8bfa3ef006220fec14b456e47406 114 Pfam PF02575 YbaB/EbfC DNA-binding family 12 100 6.5E-33 T 06-07-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family BWK49_RS02490 cb0c8bfa3ef006220fec14b456e47406 114 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 5 95 4.7E-24 T 06-07-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family BWK49_RS02490 cb0c8bfa3ef006220fec14b456e47406 114 PIRSF PIRSF004555 3 109 1.1E-41 T 06-07-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family BWK49_RS26030 5cd212f173a3ee3ce98c4856ece47f47 137 PIRSF PIRSF017349 1 137 1.7E-69 T 06-07-2017 IPR014487 Protein of unknown function DUF3151 BWK49_RS26030 5cd212f173a3ee3ce98c4856ece47f47 137 Pfam PF11349 Protein of unknown function (DUF3151) 9 133 3.8E-60 T 06-07-2017 IPR014487 Protein of unknown function DUF3151 BWK49_RS25885 2e22b23f58fc1d7c19f49af8e4e4f109 227 Gene3D G3DSA:3.20.20.70 14 224 2.7E-69 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 BWK49_RS25885 2e22b23f58fc1d7c19f49af8e4e4f109 227 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 14 224 24.284 T 06-07-2017 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 BWK49_RS25885 2e22b23f58fc1d7c19f49af8e4e4f109 227 SUPERFAMILY SSF51391 11 222 2.35E-58 T 06-07-2017 IPR022998 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 BWK49_RS25885 2e22b23f58fc1d7c19f49af8e4e4f109 227 Pfam PF02581 Thiamine monophosphate synthase/TENI 17 206 4.7E-52 T 06-07-2017 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 BWK49_RS25885 2e22b23f58fc1d7c19f49af8e4e4f109 227 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 16 219 9.1E-60 T 06-07-2017 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 BWK49_RS09425 a240ee7e934e5120fc3b02c55d28292f 498 SUPERFAMILY SSF52096 9 246 2.05E-56 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS09425 a240ee7e934e5120fc3b02c55d28292f 498 Gene3D G3DSA:3.90.226.10 253 486 1.8E-55 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS09425 a240ee7e934e5120fc3b02c55d28292f 498 Gene3D G3DSA:3.90.226.10 13 237 4.4E-52 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS09425 a240ee7e934e5120fc3b02c55d28292f 498 Pfam PF01039 Carboxyl transferase domain 33 477 1.0E-87 T 06-07-2017 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 BWK49_RS09425 a240ee7e934e5120fc3b02c55d28292f 498 SUPERFAMILY SSF52096 212 477 2.19E-58 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS22190 97ccd21e06632d42ba1cdd48295e50bc 580 Pfam PF00361 Proton-conducting membrane transporter 140 403 1.3E-57 T 06-07-2017 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS23870 5826e049f65a895b1440a0e797ede807 460 SUPERFAMILY SSF53383 11 441 1.7E-126 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase BWK49_RS23870 5826e049f65a895b1440a0e797ede807 460 Gene3D G3DSA:3.40.640.10 70 323 3.0E-28 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 BWK49_RS23870 5826e049f65a895b1440a0e797ede807 460 TIGRFAM TIGR01788 Glu-decarb-GAD: glutamate decarboxylase 15 444 3.4E-208 T 06-07-2017 IPR010107 Glutamate decarboxylase GO:0004351|GO:0006536|GO:0030170 KEGG: 00250+4.1.1.15|KEGG: 00410+4.1.1.15|KEGG: 00430+4.1.1.15|KEGG: 00650+4.1.1.15|MetaCyc: PWY-4321 BWK49_RS23870 5826e049f65a895b1440a0e797ede807 460 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 38 380 2.3E-71 T 06-07-2017 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 BWK49_RS22920 02695b840ceb57dd014b3a1ddb18de3e 585 SMART SM00909 197 295 1.9E-15 T 06-07-2017 IPR019606 GerMN domain BWK49_RS22920 02695b840ceb57dd014b3a1ddb18de3e 585 Pfam PF10646 Sporulation and spore germination 170 292 4.3E-13 T 06-07-2017 IPR019606 GerMN domain BWK49_RS22920 02695b840ceb57dd014b3a1ddb18de3e 585 Hamap MF_01373 Lipoprotein LpqB [lpqB]. 2 585 24.792 T 06-07-2017 IPR023959 Lipoprotein LpqB BWK49_RS22920 02695b840ceb57dd014b3a1ddb18de3e 585 Pfam PF10647 Lipoprotein LpqB beta-propeller domain 325 584 2.9E-69 T 06-07-2017 IPR018910 Lipoprotein LpqB, beta-propeller domain, C-terminal BWK49_RS03055 db183d5753176d2a6deab5f7b53b39a7 200 SUPERFAMILY SSF55620 12 197 2.22E-76 T 06-07-2017 BWK49_RS03055 db183d5753176d2a6deab5f7b53b39a7 200 Gene3D G3DSA:3.30.1130.10 68 197 7.6E-59 T 06-07-2017 BWK49_RS03055 db183d5753176d2a6deab5f7b53b39a7 200 Pfam PF01227 GTP cyclohydrolase I 20 197 7.3E-76 T 06-07-2017 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 BWK49_RS03055 db183d5753176d2a6deab5f7b53b39a7 200 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 21 197 4.3E-72 T 06-07-2017 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 BWK49_RS03055 db183d5753176d2a6deab5f7b53b39a7 200 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 15 198 41.705 T 06-07-2017 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 BWK49_RS03055 db183d5753176d2a6deab5f7b53b39a7 200 Gene3D G3DSA:1.10.286.10 14 66 5.6E-24 T 06-07-2017 BWK49_RS03055 db183d5753176d2a6deab5f7b53b39a7 200 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 125 135 - T 06-07-2017 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 BWK49_RS03055 db183d5753176d2a6deab5f7b53b39a7 200 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 75 91 - T 06-07-2017 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 BWK49_RS08845 e8704e932b8345238087fb8bcc713a78 123 SUPERFAMILY SSF54427 1 120 1.03E-24 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS08845 e8704e932b8345238087fb8bcc713a78 123 Gene3D G3DSA:3.10.450.50 1 120 8.5E-28 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS08845 e8704e932b8345238087fb8bcc713a78 123 Pfam PF12680 SnoaL-like domain 11 110 5.5E-14 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain BWK49_RS02660 d2539dc3409cf589b294b0dd823a4804 229 Gene3D G3DSA:3.40.50.150 12 188 6.9E-40 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS02660 d2539dc3409cf589b294b0dd823a4804 229 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 106 112 - T 06-07-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 BWK49_RS02660 d2539dc3409cf589b294b0dd823a4804 229 TIGRFAM TIGR00537 hemK_rel_arch: putative methylase 16 200 7.4E-32 T 06-07-2017 IPR004557 Eukaryotic/archaeal PrmC-related GO:0008276 Reactome: R-HSA-156581|Reactome: R-HSA-72764 BWK49_RS02660 d2539dc3409cf589b294b0dd823a4804 229 Pfam PF05175 Methyltransferase small domain 23 112 9.4E-15 T 06-07-2017 IPR007848 Methyltransferase small domain GO:0008168 BWK49_RS02660 d2539dc3409cf589b294b0dd823a4804 229 SUPERFAMILY SSF53335 10 167 5.43E-35 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS03135 7e063e242d3c54edc73337fb4109ab75 256 Gene3D G3DSA:3.40.50.1820 9 250 7.9E-38 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS03135 7e063e242d3c54edc73337fb4109ab75 256 SUPERFAMILY SSF53474 6 249 1.06E-38 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS03135 7e063e242d3c54edc73337fb4109ab75 256 Pfam PF12697 Alpha/beta hydrolase family 16 243 6.6E-16 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS28080 2190adb8d2a295688a71afc0212f3bbf 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 1.0E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS28080 2190adb8d2a295688a71afc0212f3bbf 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 1.0E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS28080 2190adb8d2a295688a71afc0212f3bbf 202 SUPERFAMILY SSF48498 91 198 3.56E-8 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS28080 2190adb8d2a295688a71afc0212f3bbf 202 Gene3D G3DSA:1.10.357.10 5 198 5.1E-32 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS28080 2190adb8d2a295688a71afc0212f3bbf 202 SUPERFAMILY SSF46689 5 84 1.64E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS28080 2190adb8d2a295688a71afc0212f3bbf 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 65 2.6E-17 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS17965 79d2f72359ab5027ef5366af846c6388 250 Pfam PF13460 NAD(P)H-binding 7 176 2.4E-9 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS17965 79d2f72359ab5027ef5366af846c6388 250 Gene3D G3DSA:3.40.50.720 1 198 7.1E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS17965 79d2f72359ab5027ef5366af846c6388 250 SUPERFAMILY SSF51735 1 205 5.33E-35 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS14835 1024189b3ec23db4beb4a5aa097acb37 178 TIGRFAM TIGR00777 ahpD: alkylhydroperoxidase, AhpD family 2 175 2.1E-83 T 06-07-2017 IPR004674 Alkylhydroperoxidase AhpD GO:0006979|GO:0032843|GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 BWK49_RS14835 1024189b3ec23db4beb4a5aa097acb37 178 Gene3D G3DSA:1.20.1290.10 1 174 8.1E-55 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 BWK49_RS14835 1024189b3ec23db4beb4a5aa097acb37 178 Pfam PF02627 Carboxymuconolactone decarboxylase family 97 172 5.9E-16 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 BWK49_RS14835 1024189b3ec23db4beb4a5aa097acb37 178 SUPERFAMILY SSF69118 3 174 1.24E-49 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 BWK49_RS14835 1024189b3ec23db4beb4a5aa097acb37 178 Hamap MF_01676 Alkyl hydroperoxide reductase AhpD [ahpD]. 1 178 82.245 T 06-07-2017 IPR004674 Alkylhydroperoxidase AhpD GO:0006979|GO:0032843|GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 BWK49_RS14835 1024189b3ec23db4beb4a5aa097acb37 178 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 111 159 1.8E-19 T 06-07-2017 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 BWK49_RS20910 64acb6d8aad69d2e9c313a4c0eba7e74 386 Pfam PF07690 Major Facilitator Superfamily 7 344 3.9E-39 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 BWK49_RS20910 64acb6d8aad69d2e9c313a4c0eba7e74 386 Gene3D G3DSA:1.20.1250.20 7 185 1.2E-24 T 06-07-2017 BWK49_RS20910 64acb6d8aad69d2e9c313a4c0eba7e74 386 SUPERFAMILY SSF103473 5 374 1.57E-55 T 06-07-2017 IPR020846 Major facilitator superfamily domain BWK49_RS20910 64acb6d8aad69d2e9c313a4c0eba7e74 386 Gene3D G3DSA:1.20.1250.20 201 373 2.5E-20 T 06-07-2017 BWK49_RS18495 13587c62815d77af5aedb7bb70ee4006 193 Hamap MF_01219 Bifunctional protein PyrR [pyrR]. 13 193 34.905 T 06-07-2017 IPR023050 Bifunctional protein PyrR KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 BWK49_RS18495 13587c62815d77af5aedb7bb70ee4006 193 Gene3D G3DSA:3.40.50.2020 14 187 2.7E-43 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like BWK49_RS18495 13587c62815d77af5aedb7bb70ee4006 193 SUPERFAMILY SSF53271 15 185 5.11E-37 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like BWK49_RS18495 13587c62815d77af5aedb7bb70ee4006 193 Pfam PF00156 Phosphoribosyl transferase domain 24 163 5.9E-17 T 06-07-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 BWK49_RS23375 3134996f4f40619a01fa7299ee1c8ad1 273 Pfam PF04185 Phosphoesterase family 46 257 8.2E-32 T 06-07-2017 IPR007312 Phosphoesterase GO:0016788 BWK49_RS23375 3134996f4f40619a01fa7299ee1c8ad1 273 SUPERFAMILY SSF53649 40 259 4.67E-8 T 06-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 BWK49_RS26785 53a3710c092c4cf4f1a7d6bfede1b26f 483 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 333 341 - T 06-07-2017 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 BWK49_RS26785 53a3710c092c4cf4f1a7d6bfede1b26f 483 Gene3D G3DSA:2.40.180.10 2 357 8.0E-154 T 06-07-2017 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 BWK49_RS26785 53a3710c092c4cf4f1a7d6bfede1b26f 483 SUPERFAMILY SSF56634 3 481 1.3E-182 T 06-07-2017 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 BWK49_RS26785 53a3710c092c4cf4f1a7d6bfede1b26f 483 Pfam PF06628 Catalase-related immune-responsive 416 478 6.5E-18 T 06-07-2017 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 BWK49_RS26785 53a3710c092c4cf4f1a7d6bfede1b26f 483 ProSitePatterns PS00438 Catalase proximal active site signature. 43 59 - T 06-07-2017 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 BWK49_RS26785 53a3710c092c4cf4f1a7d6bfede1b26f 483 PIRSF PIRSF038928 1 483 1.5E-204 T 06-07-2017 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 BWK49_RS26785 53a3710c092c4cf4f1a7d6bfede1b26f 483 PRINTS PR00067 Catalase signature 20 43 3.3E-46 T 06-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 BWK49_RS26785 53a3710c092c4cf4f1a7d6bfede1b26f 483 PRINTS PR00067 Catalase signature 104 121 3.3E-46 T 06-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 BWK49_RS26785 53a3710c092c4cf4f1a7d6bfede1b26f 483 PRINTS PR00067 Catalase signature 320 346 3.3E-46 T 06-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 BWK49_RS26785 53a3710c092c4cf4f1a7d6bfede1b26f 483 PRINTS PR00067 Catalase signature 123 141 3.3E-46 T 06-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 BWK49_RS26785 53a3710c092c4cf4f1a7d6bfede1b26f 483 PRINTS PR00067 Catalase signature 288 315 3.3E-46 T 06-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 BWK49_RS26785 53a3710c092c4cf4f1a7d6bfede1b26f 483 SMART SM01060 7 389 7.6E-239 T 06-07-2017 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 BWK49_RS26785 53a3710c092c4cf4f1a7d6bfede1b26f 483 Pfam PF00199 Catalase 7 385 9.6E-163 T 06-07-2017 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 BWK49_RS17450 c0bb45f64b7cbd6d2e8d62aa40a5ce27 728 Pfam PF01757 Acyltransferase family 35 371 6.5E-18 T 06-07-2017 IPR002656 Acyltransferase 3 GO:0016747 BWK49_RS16325 63b820a0400f918c7d4a68f903efb93d 340 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 2 303 5.2E-61 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme BWK49_RS16325 63b820a0400f918c7d4a68f903efb93d 340 Gene3D G3DSA:3.40.50.1100 72 318 3.4E-44 T 06-07-2017 BWK49_RS16325 63b820a0400f918c7d4a68f903efb93d 340 SUPERFAMILY SSF53686 2 322 1.57E-65 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme BWK49_RS16370 cba824ee89e65df2225cb9c9458ff1ff 219 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 35 3.7E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS16370 cba824ee89e65df2225cb9c9458ff1ff 219 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 66 3.7E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS16370 cba824ee89e65df2225cb9c9458ff1ff 219 SUPERFAMILY SSF46689 10 78 4.84E-19 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS16370 cba824ee89e65df2225cb9c9458ff1ff 219 Gene3D G3DSA:1.10.357.10 2 200 1.0E-40 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS16370 cba824ee89e65df2225cb9c9458ff1ff 219 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 68 2.0E-17 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS16370 cba824ee89e65df2225cb9c9458ff1ff 219 ProSitePatterns PS01081 TetR-type HTH domain signature. 34 64 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site BWK49_RS16370 cba824ee89e65df2225cb9c9458ff1ff 219 SUPERFAMILY SSF48498 89 182 7.26E-12 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS16370 cba824ee89e65df2225cb9c9458ff1ff 219 Pfam PF13305 WHG domain 98 181 8.8E-9 T 06-07-2017 IPR025996 WHG domain BWK49_RS19930 2da19a6304744d910691e10c1ad0a50d 175 Gene3D G3DSA:3.30.300.70 9 83 1.2E-13 T 06-07-2017 IPR028989 Ribosome maturation factor RimP, N-terminal BWK49_RS19930 2da19a6304744d910691e10c1ad0a50d 175 SUPERFAMILY SSF74942 87 154 4.97E-6 T 06-07-2017 IPR028998 Ribosome maturation factor RimP, C-terminal BWK49_RS19930 2da19a6304744d910691e10c1ad0a50d 175 SUPERFAMILY SSF75420 8 86 1.83E-17 T 06-07-2017 IPR028989 Ribosome maturation factor RimP, N-terminal BWK49_RS19930 2da19a6304744d910691e10c1ad0a50d 175 Pfam PF02576 Putative ribosome maturation factor RimP 19 150 3.3E-28 T 06-07-2017 IPR003728 Ribosome maturation factor RimP GO:0042274 BWK49_RS19930 2da19a6304744d910691e10c1ad0a50d 175 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 9 154 19.721 T 06-07-2017 IPR003728 Ribosome maturation factor RimP GO:0042274 BWK49_RS06525 9d107271d61514d059368846023c4df0 329 SUPERFAMILY SSF51679 1 328 2.47E-78 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS06525 9d107271d61514d059368846023c4df0 329 Pfam PF00296 Luciferase-like monooxygenase 1 298 1.3E-50 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS06525 9d107271d61514d059368846023c4df0 329 TIGRFAM TIGR03560 F420_Rv1855c: probable F420-dependent oxidoreductase, Rv1855c family 16 235 1.8E-85 T 06-07-2017 IPR019952 F420-dependent oxidoreductase-predicted, Rv1855c BWK49_RS06525 9d107271d61514d059368846023c4df0 329 Gene3D G3DSA:3.20.20.30 1 328 1.2E-86 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS26790 2941e78898d154c3e906e1556cffe279 485 SMART SM01060 7 388 1.0E-251 T 06-07-2017 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 BWK49_RS26790 2941e78898d154c3e906e1556cffe279 485 Pfam PF06628 Catalase-related immune-responsive 416 477 1.2E-16 T 06-07-2017 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 BWK49_RS26790 2941e78898d154c3e906e1556cffe279 485 PRINTS PR00067 Catalase signature 20 43 2.1E-58 T 06-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 BWK49_RS26790 2941e78898d154c3e906e1556cffe279 485 PRINTS PR00067 Catalase signature 319 345 2.1E-58 T 06-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 BWK49_RS26790 2941e78898d154c3e906e1556cffe279 485 PRINTS PR00067 Catalase signature 103 120 2.1E-58 T 06-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 BWK49_RS26790 2941e78898d154c3e906e1556cffe279 485 PRINTS PR00067 Catalase signature 82 100 2.1E-58 T 06-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 BWK49_RS26790 2941e78898d154c3e906e1556cffe279 485 PRINTS PR00067 Catalase signature 122 140 2.1E-58 T 06-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 BWK49_RS26790 2941e78898d154c3e906e1556cffe279 485 PRINTS PR00067 Catalase signature 287 314 2.1E-58 T 06-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 BWK49_RS26790 2941e78898d154c3e906e1556cffe279 485 Pfam PF00199 Catalase 7 384 2.4E-169 T 06-07-2017 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 BWK49_RS26790 2941e78898d154c3e906e1556cffe279 485 ProSitePatterns PS00438 Catalase proximal active site signature. 43 59 - T 06-07-2017 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 BWK49_RS26790 2941e78898d154c3e906e1556cffe279 485 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 332 340 - T 06-07-2017 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 BWK49_RS26790 2941e78898d154c3e906e1556cffe279 485 Gene3D G3DSA:2.40.180.10 2 356 2.0E-159 T 06-07-2017 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 BWK49_RS26790 2941e78898d154c3e906e1556cffe279 485 SUPERFAMILY SSF56634 4 479 4.97E-188 T 06-07-2017 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 BWK49_RS26790 2941e78898d154c3e906e1556cffe279 485 PIRSF PIRSF038928 1 483 1.0E-208 T 06-07-2017 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 BWK49_RS09725 15199a76f4a50b5e270e99be3efe2c16 529 Gene3D G3DSA:3.90.226.10 271 520 4.1E-92 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS09725 15199a76f4a50b5e270e99be3efe2c16 529 Gene3D G3DSA:3.90.226.10 22 269 5.6E-79 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS09725 15199a76f4a50b5e270e99be3efe2c16 529 Pfam PF01039 Carboxyl transferase domain 42 518 1.5E-146 T 06-07-2017 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 BWK49_RS09725 15199a76f4a50b5e270e99be3efe2c16 529 SUPERFAMILY SSF52096 19 265 2.41E-71 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS09725 15199a76f4a50b5e270e99be3efe2c16 529 SUPERFAMILY SSF52096 231 511 2.02E-86 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS08085 8e56c9617140e078bc24198e548f8fb6 372 Gene3D G3DSA:3.40.50.2300 138 275 4.4E-12 T 06-07-2017 BWK49_RS08085 8e56c9617140e078bc24198e548f8fb6 372 SUPERFAMILY SSF53822 8 345 2.28E-32 T 06-07-2017 IPR028082 Periplasmic binding protein-like I BWK49_RS08085 8e56c9617140e078bc24198e548f8fb6 372 Pfam PF13458 Periplasmic binding protein 9 339 1.3E-24 T 06-07-2017 IPR028081 Leucine-binding protein domain BWK49_RS08085 8e56c9617140e078bc24198e548f8fb6 372 Gene3D G3DSA:3.40.50.2300 6 136 2.4E-12 T 06-07-2017 BWK49_RS08085 8e56c9617140e078bc24198e548f8fb6 372 Gene3D G3DSA:3.40.50.2300 276 328 2.4E-12 T 06-07-2017 BWK49_RS11490 6f316522312c00d274889141f8af5688 131 Gene3D G3DSA:1.10.10.10 5 75 1.5E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS11490 6f316522312c00d274889141f8af5688 131 SUPERFAMILY SSF46785 5 127 2.04E-36 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS11490 6f316522312c00d274889141f8af5688 131 Pfam PF01475 Ferric uptake regulator family 6 122 8.2E-38 T 06-07-2017 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 BWK49_RS13795 42b0b404f79e205cebb78677df5da14c 277 Pfam PF11296 Protein of unknown function (DUF3097) 4 274 2.7E-117 T 06-07-2017 IPR021447 Protein of unknown function DUF3097 BWK49_RS17715 24da7a756dade8c3e079f07a4c8adeb1 418 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 4 79 1.5E-6 T 06-07-2017 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 BWK49_RS17715 24da7a756dade8c3e079f07a4c8adeb1 418 Gene3D G3DSA:3.40.50.2000 1 266 8.0E-59 T 06-07-2017 BWK49_RS17715 24da7a756dade8c3e079f07a4c8adeb1 418 SUPERFAMILY SSF53756 1 414 7.46E-90 T 06-07-2017 BWK49_RS17715 24da7a756dade8c3e079f07a4c8adeb1 418 Gene3D G3DSA:3.40.50.2000 296 384 3.2E-6 T 06-07-2017 BWK49_RS05500 7063a14262142ddb574e95444d047fcc 350 Pfam PF02371 Transposase IS116/IS110/IS902 family 215 293 7.3E-16 T 06-07-2017 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 BWK49_RS00845 e3ac6ef49729d495dcd754fbaf4cf3b2 101 SUPERFAMILY SSF140459 8 77 2.14E-5 T 06-07-2017 BWK49_RS00845 e3ac6ef49729d495dcd754fbaf4cf3b2 101 Pfam PF00934 PE family 2 90 2.4E-11 T 06-07-2017 IPR000084 PE-PGRS family, N-terminal BWK49_RS08075 292d432813f0e6293f2a9ce30478badb 585 Pfam PF13519 von Willebrand factor type A domain 366 480 3.1E-9 T 06-07-2017 IPR002035 von Willebrand factor, type A BWK49_RS08075 292d432813f0e6293f2a9ce30478badb 585 Gene3D G3DSA:3.40.50.410 363 549 5.6E-12 T 06-07-2017 IPR002035 von Willebrand factor, type A BWK49_RS08075 292d432813f0e6293f2a9ce30478badb 585 SMART SM00327 363 550 2.7E-16 T 06-07-2017 IPR002035 von Willebrand factor, type A BWK49_RS08075 292d432813f0e6293f2a9ce30478badb 585 SUPERFAMILY SSF53300 364 550 1.02E-18 T 06-07-2017 IPR002035 von Willebrand factor, type A BWK49_RS00210 de82deb1db90cfc97f36d55da9241e54 120 Pfam PF10774 Domain of unknown function (DUF4226) 4 115 8.6E-35 T 06-07-2017 IPR019710 Protein of unknown function DUF4226 BWK49_RS25835 8f76c0abed3dc17541d2f447c17eaa53 490 Pfam PF02225 PA domain 140 215 1.3E-5 T 06-07-2017 IPR003137 PA domain BWK49_RS25835 8f76c0abed3dc17541d2f447c17eaa53 490 SUPERFAMILY SSF53187 227 471 6.0E-44 T 06-07-2017 BWK49_RS25835 8f76c0abed3dc17541d2f447c17eaa53 490 SUPERFAMILY SSF53187 38 90 6.0E-44 T 06-07-2017 BWK49_RS25835 8f76c0abed3dc17541d2f447c17eaa53 490 SUPERFAMILY SSF52025 126 192 5.49E-5 T 06-07-2017 BWK49_RS25835 8f76c0abed3dc17541d2f447c17eaa53 490 Pfam PF04389 Peptidase family M28 243 460 1.7E-27 T 06-07-2017 IPR007484 Peptidase M28 BWK49_RS25835 8f76c0abed3dc17541d2f447c17eaa53 490 Gene3D G3DSA:3.40.630.10 242 471 1.9E-50 T 06-07-2017 BWK49_RS25835 8f76c0abed3dc17541d2f447c17eaa53 490 Gene3D G3DSA:3.40.630.10 39 101 1.9E-50 T 06-07-2017 BWK49_RS25835 8f76c0abed3dc17541d2f447c17eaa53 490 Gene3D G3DSA:3.50.30.30 124 211 2.9E-7 T 06-07-2017 BWK49_RS26100 761c4b3faad7c061ed7b1ede34b1e5fb 396 Pfam PF00970 Oxidoreductase FAD-binding domain 157 247 6.3E-16 T 06-07-2017 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 BWK49_RS26100 761c4b3faad7c061ed7b1ede34b1e5fb 396 Pfam PF00042 Globin 29 111 1.7E-7 T 06-07-2017 IPR000971 Globin GO:0019825|GO:0020037 BWK49_RS26100 761c4b3faad7c061ed7b1ede34b1e5fb 396 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 258 277 4.5E-5 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 BWK49_RS26100 761c4b3faad7c061ed7b1ede34b1e5fb 396 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 283 292 4.5E-5 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 BWK49_RS26100 761c4b3faad7c061ed7b1ede34b1e5fb 396 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 181 191 4.5E-5 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 BWK49_RS26100 761c4b3faad7c061ed7b1ede34b1e5fb 396 Gene3D G3DSA:2.40.30.10 151 246 2.7E-19 T 06-07-2017 BWK49_RS26100 761c4b3faad7c061ed7b1ede34b1e5fb 396 SUPERFAMILY SSF52343 251 392 4.58E-23 T 06-07-2017 BWK49_RS26100 761c4b3faad7c061ed7b1ede34b1e5fb 396 SUPERFAMILY SSF46458 28 145 3.49E-23 T 06-07-2017 IPR009050 Globin-like BWK49_RS26100 761c4b3faad7c061ed7b1ede34b1e5fb 396 PRINTS PR00410 Phenol hydroxylase reductase family signature 181 193 8.8E-12 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 BWK49_RS26100 761c4b3faad7c061ed7b1ede34b1e5fb 396 PRINTS PR00410 Phenol hydroxylase reductase family signature 283 292 8.8E-12 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 BWK49_RS26100 761c4b3faad7c061ed7b1ede34b1e5fb 396 PRINTS PR00410 Phenol hydroxylase reductase family signature 258 277 8.8E-12 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 BWK49_RS26100 761c4b3faad7c061ed7b1ede34b1e5fb 396 Pfam PF00175 Oxidoreductase NAD-binding domain 259 376 1.7E-5 T 06-07-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 BWK49_RS26100 761c4b3faad7c061ed7b1ede34b1e5fb 396 Gene3D G3DSA:1.10.490.10 28 145 1.4E-20 T 06-07-2017 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 BWK49_RS26100 761c4b3faad7c061ed7b1ede34b1e5fb 396 Gene3D G3DSA:3.40.50.80 254 392 3.9E-24 T 06-07-2017 BWK49_RS26100 761c4b3faad7c061ed7b1ede34b1e5fb 396 SUPERFAMILY SSF63380 153 247 1.11E-19 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 BWK49_RS09010 db6e7e4f05e23dc7900058f4abe84cb0 390 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 306 386 2.3E-19 T 06-07-2017 IPR022171 PPE family, C-terminal BWK49_RS09010 db6e7e4f05e23dc7900058f4abe84cb0 390 SUPERFAMILY SSF140459 3 175 3.14E-60 T 06-07-2017 BWK49_RS09010 db6e7e4f05e23dc7900058f4abe84cb0 390 Pfam PF00823 PPE family 6 161 2.5E-59 T 06-07-2017 IPR000030 PPE family BWK49_RS22240 a12b16a05aaf6567d4d9ab78bd376440 219 TIGRFAM TIGR03914 UDG_fam_dom: uracil-DNA glycosylase family domain 15 213 1.5E-73 T 06-07-2017 IPR005273 Uracil-DNA glycosylase, family 4 domain BWK49_RS22240 a12b16a05aaf6567d4d9ab78bd376440 219 Pfam PF03167 Uracil DNA glycosylase superfamily 44 211 3.0E-35 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 BWK49_RS22240 a12b16a05aaf6567d4d9ab78bd376440 219 SMART SM00987 44 212 9.0E-37 T 06-07-2017 BWK49_RS22240 a12b16a05aaf6567d4d9ab78bd376440 219 SMART SM00986 44 212 9.0E-37 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 BWK49_RS22240 a12b16a05aaf6567d4d9ab78bd376440 219 TIGRFAM TIGR00758 UDG_fam4: uracil-DNA glycosylase, family 4 30 202 3.2E-37 T 06-07-2017 IPR005273 Uracil-DNA glycosylase, family 4 domain BWK49_RS22240 a12b16a05aaf6567d4d9ab78bd376440 219 SUPERFAMILY SSF52141 18 215 7.19E-50 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 BWK49_RS22240 a12b16a05aaf6567d4d9ab78bd376440 219 Gene3D G3DSA:3.40.470.10 19 216 4.1E-61 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 BWK49_RS09695 e0a9ebb0ed1889f23b2b68302c81cd34 215 Gene3D G3DSA:3.30.420.10 3 178 4.0E-68 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS09695 e0a9ebb0ed1889f23b2b68302c81cd34 215 SMART SM00479 4 179 1.4E-33 T 06-07-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III BWK49_RS09695 e0a9ebb0ed1889f23b2b68302c81cd34 215 SUPERFAMILY SSF53098 4 177 6.68E-44 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS09695 e0a9ebb0ed1889f23b2b68302c81cd34 215 Hamap MF_00045 Oligoribonuclease [orn]. 1 180 37.782 T 06-07-2017 IPR022894 Oligoribonuclease GO:0016788 BWK49_RS09695 e0a9ebb0ed1889f23b2b68302c81cd34 215 Pfam PF00929 Exonuclease 6 169 1.3E-30 T 06-07-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III BWK49_RS12235 0ae0ed76f1f1b2a3e9c798ae07bdd888 221 Gene3D G3DSA:1.10.357.10 32 207 4.8E-20 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS12235 0ae0ed76f1f1b2a3e9c798ae07bdd888 221 ProSitePatterns PS01081 TetR-type HTH domain signature. 46 77 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site BWK49_RS12235 0ae0ed76f1f1b2a3e9c798ae07bdd888 221 Pfam PF00440 Bacterial regulatory proteins, tetR family 34 80 1.9E-15 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS12235 0ae0ed76f1f1b2a3e9c798ae07bdd888 221 SUPERFAMILY SSF46689 29 91 4.24E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS13185 f1fd1cfe107eee7d8aa1015ed0b6dd3b 195 Pfam PF11290 Protein of unknown function (DUF3090) 6 175 1.8E-68 T 06-07-2017 IPR021441 Protein of unknown function DUF3090 BWK49_RS13185 f1fd1cfe107eee7d8aa1015ed0b6dd3b 195 TIGRFAM TIGR03847 TIGR03847: conserved hypothetical protein 5 179 1.0E-77 T 06-07-2017 IPR021441 Protein of unknown function DUF3090 BWK49_RS23660 701a1b5253a0d1908c400e390569c2e8 1058 Pfam PF02754 Cysteine-rich domain 782 853 0.0058 T 06-07-2017 IPR004017 Cysteine-rich domain BWK49_RS23660 701a1b5253a0d1908c400e390569c2e8 1058 Pfam PF02754 Cysteine-rich domain 919 985 0.059 T 06-07-2017 IPR004017 Cysteine-rich domain BWK49_RS23660 701a1b5253a0d1908c400e390569c2e8 1058 Pfam PF01565 FAD binding domain 68 210 8.2E-32 T 06-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 BWK49_RS23660 701a1b5253a0d1908c400e390569c2e8 1058 Gene3D G3DSA:3.30.465.10 123 218 7.0E-25 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 BWK49_RS23660 701a1b5253a0d1908c400e390569c2e8 1058 Gene3D G3DSA:3.30.465.10 252 301 7.0E-25 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 BWK49_RS23660 701a1b5253a0d1908c400e390569c2e8 1058 Pfam PF02913 FAD linked oxidases, C-terminal domain 304 558 2.4E-46 T 06-07-2017 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 BWK49_RS23660 701a1b5253a0d1908c400e390569c2e8 1058 Gene3D G3DSA:1.10.1060.10 538 683 3.3E-12 T 06-07-2017 BWK49_RS23660 701a1b5253a0d1908c400e390569c2e8 1058 SUPERFAMILY SSF56176 35 300 1.12E-45 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 BWK49_RS23660 701a1b5253a0d1908c400e390569c2e8 1058 Pfam PF13183 4Fe-4S dicluster domain 597 674 2.2E-10 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain BWK49_RS23660 701a1b5253a0d1908c400e390569c2e8 1058 SUPERFAMILY SSF46548 581 679 8.89E-10 T 06-07-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 BWK49_RS23660 701a1b5253a0d1908c400e390569c2e8 1058 Gene3D G3DSA:3.30.43.10 37 118 3.4E-18 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 BWK49_RS23660 701a1b5253a0d1908c400e390569c2e8 1058 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 660 671 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site BWK49_RS23660 701a1b5253a0d1908c400e390569c2e8 1058 SUPERFAMILY SSF55103 305 568 4.25E-46 T 06-07-2017 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 BWK49_RS15130 b0c2418f0b2fb316ca6159f591f9fdd1 639 SMART SM00382 452 633 1.5E-8 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS15130 b0c2418f0b2fb316ca6159f591f9fdd1 639 Pfam PF06472 ABC transporter transmembrane region 2 44 358 6.4E-90 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 BWK49_RS15130 b0c2418f0b2fb316ca6159f591f9fdd1 639 Pfam PF00005 ABC transporter 444 579 1.4E-15 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 BWK49_RS15130 b0c2418f0b2fb316ca6159f591f9fdd1 639 ProSitePatterns PS00211 ABC transporters family signature. 551 565 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 BWK49_RS15130 b0c2418f0b2fb316ca6159f591f9fdd1 639 Gene3D G3DSA:3.40.50.300 425 630 2.4E-32 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS15130 b0c2418f0b2fb316ca6159f591f9fdd1 639 Gene3D G3DSA:1.20.1560.10 212 406 8.6E-5 T 06-07-2017 BWK49_RS15130 b0c2418f0b2fb316ca6159f591f9fdd1 639 SUPERFAMILY SSF52540 416 633 1.08E-32 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS15130 b0c2418f0b2fb316ca6159f591f9fdd1 639 SUPERFAMILY SSF90123 67 391 1.19E-12 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 BWK49_RS15130 b0c2418f0b2fb316ca6159f591f9fdd1 639 SUPERFAMILY SSF90123 555 564 1.19E-12 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 BWK49_RS06000 79100a94e8f1457a090bb47e5848ca9c 388 SUPERFAMILY SSF51556 37 73 3.86E-54 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS06000 79100a94e8f1457a090bb47e5848ca9c 388 SUPERFAMILY SSF51556 104 388 3.86E-54 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS06000 79100a94e8f1457a090bb47e5848ca9c 388 Gene3D G3DSA:3.20.20.140 72 388 3.2E-43 T 06-07-2017 BWK49_RS06000 79100a94e8f1457a090bb47e5848ca9c 388 Pfam PF04909 Amidohydrolase 136 388 9.6E-22 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 BWK49_RS15990 f6487bf309156e4ea67fdf8e212b28d0 67 PIRSF PIRSF002599 1 67 4.7E-25 T 06-07-2017 IPR012156 Cold shock, CspA GO:0003676 BWK49_RS15990 f6487bf309156e4ea67fdf8e212b28d0 67 SMART SM00357 3 67 1.4E-29 T 06-07-2017 IPR011129 Cold shock protein GO:0003676 BWK49_RS15990 f6487bf309156e4ea67fdf8e212b28d0 67 PRINTS PR00050 Cold shock protein signature 4 19 4.5E-17 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 BWK49_RS15990 f6487bf309156e4ea67fdf8e212b28d0 67 PRINTS PR00050 Cold shock protein signature 40 58 4.5E-17 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 BWK49_RS15990 f6487bf309156e4ea67fdf8e212b28d0 67 PRINTS PR00050 Cold shock protein signature 25 34 4.5E-17 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 BWK49_RS15990 f6487bf309156e4ea67fdf8e212b28d0 67 SUPERFAMILY SSF50249 1 66 1.39E-25 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS15990 f6487bf309156e4ea67fdf8e212b28d0 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 06-07-2017 IPR019844 Cold-shock conserved site BWK49_RS15990 f6487bf309156e4ea67fdf8e212b28d0 67 Gene3D G3DSA:2.40.50.140 1 65 4.1E-32 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS15990 f6487bf309156e4ea67fdf8e212b28d0 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 66 5.4E-31 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 BWK49_RS06670 1d0959f8e7a7811883802023d56705de 376 Gene3D G3DSA:3.90.1150.10 258 371 4.2E-8 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 BWK49_RS06670 1d0959f8e7a7811883802023d56705de 376 PIRSF PIRSF000525 7 376 1.4E-80 T 06-07-2017 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 BWK49_RS06670 1d0959f8e7a7811883802023d56705de 376 Pfam PF00266 Aminotransferase class-V 33 335 4.9E-18 T 06-07-2017 IPR000192 Aminotransferase class V domain BWK49_RS06670 1d0959f8e7a7811883802023d56705de 376 Hamap MF_00160 Phosphoserine aminotransferase [serC]. 10 376 25.019 T 06-07-2017 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 BWK49_RS06670 1d0959f8e7a7811883802023d56705de 376 SUPERFAMILY SSF53383 22 375 2.82E-78 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase BWK49_RS06670 1d0959f8e7a7811883802023d56705de 376 TIGRFAM TIGR01366 serC_3: putative phosphoserine aminotransferase 16 376 1.3E-212 T 06-07-2017 IPR006272 Phosphoserine aminotransferase, Mycobacterial-type GO:0004648|GO:0006564|GO:0009058 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52 BWK49_RS06670 1d0959f8e7a7811883802023d56705de 376 Gene3D G3DSA:3.40.640.10 24 257 1.5E-52 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 BWK49_RS05040 81388a85310b910fd91d845f7ffa3fa0 209 Pfam PF13384 Homeodomain-like domain 2 47 1.3E-6 T 06-07-2017 BWK49_RS26965 0cfdfd41d85631556ee84d8ea344e99d 182 SUPERFAMILY SSF48498 73 182 1.17E-28 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS26965 0cfdfd41d85631556ee84d8ea344e99d 182 Gene3D G3DSA:1.10.10.60 2 51 1.1E-19 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS26965 0cfdfd41d85631556ee84d8ea344e99d 182 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 6 19 7.2E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS26965 0cfdfd41d85631556ee84d8ea344e99d 182 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 50 7.2E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS26965 0cfdfd41d85631556ee84d8ea344e99d 182 Gene3D G3DSA:1.10.357.10 57 182 1.8E-40 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS26965 0cfdfd41d85631556ee84d8ea344e99d 182 Pfam PF00440 Bacterial regulatory proteins, tetR family 6 51 3.1E-14 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS26965 0cfdfd41d85631556ee84d8ea344e99d 182 SUPERFAMILY SSF46689 2 70 6.67E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS12405 c8f119dc206c3bc47d932c3d4a4a4d56 272 SUPERFAMILY SSF56601 7 267 3.64E-53 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like BWK49_RS12405 c8f119dc206c3bc47d932c3d4a4a4d56 272 Gene3D G3DSA:3.40.710.10 9 267 2.7E-44 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like BWK49_RS12405 c8f119dc206c3bc47d932c3d4a4a4d56 272 Pfam PF00144 Beta-lactamase 15 253 6.5E-36 T 06-07-2017 IPR001466 Beta-lactamase-related BWK49_RS04070 fefbb9798f75b82214fe9d46b8051307 61 Pfam PF11273 Protein of unknown function (DUF3073) 2 59 5.0E-22 T 06-07-2017 IPR021426 Protein of unknown function DUF3073 BWK49_RS07195 e8b0ffdc434b6454cad174831bcbfffe 389 SUPERFAMILY SSF50022 25 170 1.15E-39 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS07195 e8b0ffdc434b6454cad174831bcbfffe 389 Gene3D G3DSA:3.90.380.10 162 369 4.8E-12 T 06-07-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 BWK49_RS07195 e8b0ffdc434b6454cad174831bcbfffe 389 SUPERFAMILY SSF55961 176 385 3.66E-28 T 06-07-2017 BWK49_RS07195 e8b0ffdc434b6454cad174831bcbfffe 389 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 210 381 7.4E-20 T 06-07-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 BWK49_RS07195 e8b0ffdc434b6454cad174831bcbfffe 389 Gene3D G3DSA:2.102.10.10 61 161 4.2E-30 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS07195 e8b0ffdc434b6454cad174831bcbfffe 389 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 74 89 2.4E-5 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS07195 e8b0ffdc434b6454cad174831bcbfffe 389 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 44 69 2.4E-5 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS07195 e8b0ffdc434b6454cad174831bcbfffe 389 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 115 135 2.4E-5 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS07195 e8b0ffdc434b6454cad174831bcbfffe 389 Pfam PF00355 Rieske [2Fe-2S] domain 63 142 7.8E-15 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS02430 941f8385a7e97b42cebd808e6f789b8c 57 Gene3D G3DSA:1.10.1470.10 4 57 2.9E-11 T 06-07-2017 IPR008462 CsbD-like BWK49_RS02430 941f8385a7e97b42cebd808e6f789b8c 57 SUPERFAMILY SSF69047 4 56 2.09E-7 T 06-07-2017 IPR008462 CsbD-like BWK49_RS02430 941f8385a7e97b42cebd808e6f789b8c 57 Pfam PF05532 CsbD-like 5 57 6.6E-15 T 06-07-2017 IPR008462 CsbD-like BWK49_RS23980 ff140b4f2081e18fc916847c2ea3c44d 293 SMART SM01110 36 221 1.2E-81 T 06-07-2017 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 BWK49_RS23980 ff140b4f2081e18fc916847c2ea3c44d 293 Pfam PF01083 Cutinase 38 221 1.6E-49 T 06-07-2017 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 BWK49_RS23980 ff140b4f2081e18fc916847c2ea3c44d 293 SUPERFAMILY SSF53474 30 221 1.13E-36 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS23980 ff140b4f2081e18fc916847c2ea3c44d 293 Gene3D G3DSA:3.40.50.1820 28 221 3.3E-50 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS23980 ff140b4f2081e18fc916847c2ea3c44d 293 ProSitePatterns PS00155 Cutinase, serine active site. 110 122 - T 06-07-2017 IPR011150 Cutinase, monofunctional GO:0005576|GO:0050525 BWK49_RS23710 9610e3a75041a4bf7615b9d2819fba23 226 ProSitePatterns PS01081 TetR-type HTH domain signature. 35 66 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site BWK49_RS23710 9610e3a75041a4bf7615b9d2819fba23 226 Gene3D G3DSA:1.10.357.10 15 204 1.9E-26 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS23710 9610e3a75041a4bf7615b9d2819fba23 226 SUPERFAMILY SSF48498 129 203 2.97E-7 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS23710 9610e3a75041a4bf7615b9d2819fba23 226 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 3.3E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS23710 9610e3a75041a4bf7615b9d2819fba23 226 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 3.3E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS23710 9610e3a75041a4bf7615b9d2819fba23 226 SUPERFAMILY SSF46689 16 85 8.72E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS23710 9610e3a75041a4bf7615b9d2819fba23 226 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 69 2.4E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS13160 25ec191e4c16ccedbe28f7c3404ad7bb 366 Hamap MF_00225 Dihydroorotate dehydrogenase (quinone) [pyrD]. 13 344 46.78 T 06-07-2017 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 BWK49_RS13160 25ec191e4c16ccedbe28f7c3404ad7bb 366 TIGRFAM TIGR01036 pyrD_sub2: dihydroorotate dehydrogenase (fumarate) 14 365 3.0E-142 T 06-07-2017 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 BWK49_RS13160 25ec191e4c16ccedbe28f7c3404ad7bb 366 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 300 320 - T 06-07-2017 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 BWK49_RS13160 25ec191e4c16ccedbe28f7c3404ad7bb 366 Gene3D G3DSA:3.20.20.70 14 364 7.0E-117 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 BWK49_RS13160 25ec191e4c16ccedbe28f7c3404ad7bb 366 Pfam PF01180 Dihydroorotate dehydrogenase 61 348 4.8E-98 T 06-07-2017 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 BWK49_RS13160 25ec191e4c16ccedbe28f7c3404ad7bb 366 SUPERFAMILY SSF51395 14 363 7.94E-94 T 06-07-2017 BWK49_RS13160 25ec191e4c16ccedbe28f7c3404ad7bb 366 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 96 115 - T 06-07-2017 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 BWK49_RS24570 a09f328cdf5b3492652c158c64710b54 232 Pfam PF03795 YCII-related domain 139 218 1.0E-6 T 06-07-2017 IPR005545 YCII-related BWK49_RS24570 a09f328cdf5b3492652c158c64710b54 232 Pfam PF03795 YCII-related domain 2 108 3.9E-13 T 06-07-2017 IPR005545 YCII-related BWK49_RS24570 a09f328cdf5b3492652c158c64710b54 232 SUPERFAMILY SSF54909 125 221 1.34E-19 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel BWK49_RS24570 a09f328cdf5b3492652c158c64710b54 232 SUPERFAMILY SSF54909 1 108 2.95E-21 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel BWK49_RS24570 a09f328cdf5b3492652c158c64710b54 232 Gene3D G3DSA:3.30.70.1060 1 109 1.2E-25 T 06-07-2017 BWK49_RS24570 a09f328cdf5b3492652c158c64710b54 232 Gene3D G3DSA:3.30.70.1060 122 228 1.8E-23 T 06-07-2017 BWK49_RS25445 8a28349e87f2df0ef16370f225e8ba36 138 SMART SM00530 25 80 3.3E-14 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 BWK49_RS25445 8a28349e87f2df0ef16370f225e8ba36 138 Gene3D G3DSA:1.10.260.40 22 117 7.8E-19 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 BWK49_RS25445 8a28349e87f2df0ef16370f225e8ba36 138 Pfam PF01381 Helix-turn-helix 26 79 7.1E-14 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 BWK49_RS25445 8a28349e87f2df0ef16370f225e8ba36 138 SUPERFAMILY SSF47413 18 82 6.48E-16 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 BWK49_RS06995 5dd4e743fa12f29a584580dc7e622e3d 298 ProDom PD026943 MEMBRANE ANTIGEN TRANSMEMBRANE ANTIGENIC HOMOLOG PRECURSOR MLCB373.06 SIGNAL 20 170 4.0E-24 T 06-07-2017 BWK49_RS23160 e0f1e1ee4ab9ad9de8df7b7a759ebd76 522 Gene3D G3DSA:3.50.50.60 179 286 1.3E-55 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS23160 e0f1e1ee4ab9ad9de8df7b7a759ebd76 522 Gene3D G3DSA:3.50.50.60 458 517 1.3E-55 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS23160 e0f1e1ee4ab9ad9de8df7b7a759ebd76 522 Gene3D G3DSA:3.50.50.60 9 141 1.3E-55 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS23160 e0f1e1ee4ab9ad9de8df7b7a759ebd76 522 Pfam PF00890 FAD binding domain 16 502 6.8E-89 T 06-07-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 BWK49_RS23160 e0f1e1ee4ab9ad9de8df7b7a759ebd76 522 Gene3D G3DSA:3.90.700.10 303 450 2.8E-32 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 BWK49_RS23160 e0f1e1ee4ab9ad9de8df7b7a759ebd76 522 SUPERFAMILY SSF51905 174 250 4.33E-34 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS23160 e0f1e1ee4ab9ad9de8df7b7a759ebd76 522 SUPERFAMILY SSF51905 459 519 4.33E-34 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS23160 e0f1e1ee4ab9ad9de8df7b7a759ebd76 522 SUPERFAMILY SSF51905 11 140 4.33E-34 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS23160 e0f1e1ee4ab9ad9de8df7b7a759ebd76 522 SUPERFAMILY SSF56425 290 458 6.73E-33 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 BWK49_RS11085 cb2e36197f9a48705072e82ec38e44b5 134 SUPERFAMILY SSF50249 4 126 1.64E-32 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS11085 cb2e36197f9a48705072e82ec38e44b5 134 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 17 53 2.4E-8 T 06-07-2017 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal BWK49_RS11085 cb2e36197f9a48705072e82ec38e44b5 134 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 56 118 2.0E-15 T 06-07-2017 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal BWK49_RS04810 416dc83b4bf366156c1a3406d3ec39bb 412 Pfam PF02371 Transposase IS116/IS110/IS902 family 275 359 1.2E-13 T 06-07-2017 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 BWK49_RS04810 416dc83b4bf366156c1a3406d3ec39bb 412 Pfam PF01548 Transposase 4 161 1.2E-33 T 06-07-2017 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 BWK49_RS17350 76e6c3f65c0902e2722855bb99b4fea4 526 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 10 496 9.2E-194 T 06-07-2017 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 BWK49_RS17350 76e6c3f65c0902e2722855bb99b4fea4 526 SUPERFAMILY SSF46977 422 514 9.42E-19 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 BWK49_RS17350 76e6c3f65c0902e2722855bb99b4fea4 526 SUPERFAMILY SSF56425 229 344 8.22E-34 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 BWK49_RS17350 76e6c3f65c0902e2722855bb99b4fea4 526 Gene3D G3DSA:3.90.700.10 235 340 4.8E-32 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 BWK49_RS17350 76e6c3f65c0902e2722855bb99b4fea4 526 Gene3D G3DSA:3.50.50.60 341 402 1.4E-85 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS17350 76e6c3f65c0902e2722855bb99b4fea4 526 Gene3D G3DSA:3.50.50.60 3 234 1.4E-85 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS17350 76e6c3f65c0902e2722855bb99b4fea4 526 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 12 34 1.2E-5 T 06-07-2017 BWK49_RS17350 76e6c3f65c0902e2722855bb99b4fea4 526 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 362 369 1.2E-5 T 06-07-2017 BWK49_RS17350 76e6c3f65c0902e2722855bb99b4fea4 526 Pfam PF00890 FAD binding domain 12 384 5.4E-90 T 06-07-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 BWK49_RS17350 76e6c3f65c0902e2722855bb99b4fea4 526 Gene3D G3DSA:1.20.58.100 419 508 8.2E-14 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 BWK49_RS17350 76e6c3f65c0902e2722855bb99b4fea4 526 Pfam PF02910 Fumarate reductase flavoprotein C-term 471 502 4.9E-6 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 BWK49_RS17350 76e6c3f65c0902e2722855bb99b4fea4 526 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 347 369 3.2E-10 T 06-07-2017 BWK49_RS17350 76e6c3f65c0902e2722855bb99b4fea4 526 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 13 32 3.2E-10 T 06-07-2017 BWK49_RS17350 76e6c3f65c0902e2722855bb99b4fea4 526 SUPERFAMILY SSF51905 9 226 8.15E-53 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS17350 76e6c3f65c0902e2722855bb99b4fea4 526 SUPERFAMILY SSF51905 343 405 8.15E-53 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS07715 adbe16164526702d6b37db2c9a675eb2 320 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 76 255 4.1E-17 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain BWK49_RS07715 adbe16164526702d6b37db2c9a675eb2 320 Gene3D G3DSA:3.40.50.1110 72 268 6.1E-23 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain BWK49_RS07715 adbe16164526702d6b37db2c9a675eb2 320 SUPERFAMILY SSF52266 72 269 9.47E-30 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain BWK49_RS03445 52e74d1862b10c691180daf8a49590cc 560 SUPERFAMILY SSF56425 316 495 1.26E-34 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 BWK49_RS03445 52e74d1862b10c691180daf8a49590cc 560 Pfam PF00890 FAD binding domain 7 541 8.6E-93 T 06-07-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 BWK49_RS03445 52e74d1862b10c691180daf8a49590cc 560 Gene3D G3DSA:3.90.700.10 326 493 2.4E-36 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 BWK49_RS03445 52e74d1862b10c691180daf8a49590cc 560 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 205 230 2.6E-7 T 06-07-2017 BWK49_RS03445 52e74d1862b10c691180daf8a49590cc 560 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 2.6E-7 T 06-07-2017 BWK49_RS03445 52e74d1862b10c691180daf8a49590cc 560 SUPERFAMILY SSF51905 212 321 7.46E-44 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS03445 52e74d1862b10c691180daf8a49590cc 560 SUPERFAMILY SSF51905 4 119 7.46E-44 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS03445 52e74d1862b10c691180daf8a49590cc 560 SUPERFAMILY SSF51905 500 558 7.46E-44 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS03445 52e74d1862b10c691180daf8a49590cc 560 Gene3D G3DSA:3.50.50.60 497 558 5.7E-67 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS03445 52e74d1862b10c691180daf8a49590cc 560 Gene3D G3DSA:3.50.50.60 203 315 5.7E-67 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS03445 52e74d1862b10c691180daf8a49590cc 560 Gene3D G3DSA:3.50.50.60 3 139 5.7E-67 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS18165 df69344ce8979712533927353ed9c81e 270 Pfam PF13412 Winged helix-turn-helix DNA-binding 36 78 1.0E-7 T 06-07-2017 BWK49_RS18165 df69344ce8979712533927353ed9c81e 270 SUPERFAMILY SSF46785 37 225 1.01E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS18165 df69344ce8979712533927353ed9c81e 270 Gene3D G3DSA:1.10.10.10 36 146 5.6E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS15880 b4644c68156047fac28b5522283c3d5d 567 Gene3D G3DSA:3.90.700.10 328 485 7.1E-30 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 BWK49_RS15880 b4644c68156047fac28b5522283c3d5d 567 Pfam PF00890 FAD binding domain 7 535 1.5E-88 T 06-07-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 BWK49_RS15880 b4644c68156047fac28b5522283c3d5d 567 SUPERFAMILY SSF56425 311 487 6.28E-31 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 BWK49_RS15880 b4644c68156047fac28b5522283c3d5d 567 Gene3D G3DSA:3.50.50.60 203 310 3.4E-54 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS15880 b4644c68156047fac28b5522283c3d5d 567 Gene3D G3DSA:3.50.50.60 491 551 3.4E-54 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS15880 b4644c68156047fac28b5522283c3d5d 567 Gene3D G3DSA:3.50.50.60 3 138 3.4E-54 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS15880 b4644c68156047fac28b5522283c3d5d 567 SUPERFAMILY SSF51905 5 124 5.86E-33 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS15880 b4644c68156047fac28b5522283c3d5d 567 SUPERFAMILY SSF51905 208 307 5.86E-33 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS15880 b4644c68156047fac28b5522283c3d5d 567 SUPERFAMILY SSF51905 166 171 5.86E-33 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS15880 b4644c68156047fac28b5522283c3d5d 567 SUPERFAMILY SSF51905 489 551 5.86E-33 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS17320 28bddf0445a7a2b33841a4d55d5dffd5 206 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 5 205 30.921 T 06-07-2017 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 BWK49_RS17320 28bddf0445a7a2b33841a4d55d5dffd5 206 SUPERFAMILY SSF52317 4 204 7.92E-54 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like BWK49_RS17320 28bddf0445a7a2b33841a4d55d5dffd5 206 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 6 204 1.1E-65 T 06-07-2017 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 BWK49_RS17320 28bddf0445a7a2b33841a4d55d5dffd5 206 Gene3D G3DSA:3.40.50.880 3 204 4.4E-72 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like BWK49_RS17320 28bddf0445a7a2b33841a4d55d5dffd5 206 PIRSF PIRSF000495 4 206 2.6E-60 T 06-07-2017 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 BWK49_RS17320 28bddf0445a7a2b33841a4d55d5dffd5 206 Pfam PF00117 Glutamine amidotransferase class-I 8 201 6.8E-17 T 06-07-2017 IPR017926 Glutamine amidotransferase BWK49_RS10955 eff972002318296edc53f80bb0c2bb9f 800 Pfam PF02515 CoA-transferase family III 398 770 1.5E-101 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 BWK49_RS10955 eff972002318296edc53f80bb0c2bb9f 800 Pfam PF02515 CoA-transferase family III 5 368 4.7E-75 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 BWK49_RS10955 eff972002318296edc53f80bb0c2bb9f 800 SUPERFAMILY SSF89796 3 374 5.36E-81 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS10955 eff972002318296edc53f80bb0c2bb9f 800 Gene3D G3DSA:3.30.1540.10 619 700 2.4E-24 T 06-07-2017 BWK49_RS10955 eff972002318296edc53f80bb0c2bb9f 800 Gene3D G3DSA:3.30.1540.10 237 307 4.6E-11 T 06-07-2017 BWK49_RS10955 eff972002318296edc53f80bb0c2bb9f 800 Gene3D G3DSA:3.40.50.10540 701 793 1.4E-88 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS10955 eff972002318296edc53f80bb0c2bb9f 800 Gene3D G3DSA:3.40.50.10540 308 374 3.2E-70 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS10955 eff972002318296edc53f80bb0c2bb9f 800 Gene3D G3DSA:3.40.50.10540 2 221 3.2E-70 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS10955 eff972002318296edc53f80bb0c2bb9f 800 Gene3D G3DSA:3.40.50.10540 394 612 1.4E-88 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS10955 eff972002318296edc53f80bb0c2bb9f 800 SUPERFAMILY SSF89796 395 793 3.14E-106 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS25955 0264da39c45e58628f43ad16cc98d94a 394 SUPERFAMILY SSF56645 9 239 7.33E-76 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS25955 0264da39c45e58628f43ad16cc98d94a 394 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 240 385 7.6E-28 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS25955 0264da39c45e58628f43ad16cc98d94a 394 Gene3D G3DSA:1.20.140.10 229 389 1.8E-40 T 06-07-2017 BWK49_RS25955 0264da39c45e58628f43ad16cc98d94a 394 Gene3D G3DSA:1.10.540.10 8 135 8.2E-40 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS25955 0264da39c45e58628f43ad16cc98d94a 394 Gene3D G3DSA:2.40.110.10 137 228 3.6E-37 T 06-07-2017 BWK49_RS25955 0264da39c45e58628f43ad16cc98d94a 394 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 22 134 1.8E-28 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS25955 0264da39c45e58628f43ad16cc98d94a 394 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 138 228 5.4E-24 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 BWK49_RS25955 0264da39c45e58628f43ad16cc98d94a 394 SUPERFAMILY SSF47203 244 390 5.96E-38 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS15230 821fa1852fe214c268dc3dd25302cf34 503 TIGRFAM TIGR03920 T7SS_EccD: type VII secretion integral membrane protein EccD 23 502 6.5E-120 T 06-07-2017 IPR006707 Type VII secretion system membrane protein EccD BWK49_RS15230 821fa1852fe214c268dc3dd25302cf34 503 Pfam PF08817 WXG100 protein secretion system (Wss), protein YukD 23 103 6.2E-12 T 06-07-2017 IPR024962 YukD-like BWK49_RS15230 821fa1852fe214c268dc3dd25302cf34 503 PIRSF PIRSF017804 15 503 8.4E-49 T 06-07-2017 IPR006707 Type VII secretion system membrane protein EccD BWK49_RS10190 d1fba4dd8e3c491e96a8bf0312132d37 280 Hamap MF_01818 Ribonuclease BN [rbn]. 2 276 22.771 T 06-07-2017 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 BWK49_RS10190 d1fba4dd8e3c491e96a8bf0312132d37 280 Gene3D G3DSA:3.60.15.10 3 277 1.7E-52 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS10190 d1fba4dd8e3c491e96a8bf0312132d37 280 SMART SM00849 19 218 5.1E-9 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS10190 d1fba4dd8e3c491e96a8bf0312132d37 280 Pfam PF12706 Beta-lactamase superfamily domain 32 241 2.0E-16 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS10190 d1fba4dd8e3c491e96a8bf0312132d37 280 SUPERFAMILY SSF56281 3 274 9.7E-52 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS11790 4404935df1f03e813efab710e0d731c1 291 Gene3D G3DSA:3.10.310.10 138 265 2.1E-6 T 06-07-2017 BWK49_RS11790 4404935df1f03e813efab710e0d731c1 291 Gene3D G3DSA:3.10.310.10 1 137 1.9E-25 T 06-07-2017 BWK49_RS11790 4404935df1f03e813efab710e0d731c1 291 Pfam PF01678 Diaminopimelate epimerase 3 139 4.7E-19 T 06-07-2017 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 BWK49_RS11790 4404935df1f03e813efab710e0d731c1 291 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 1 281 3.4E-36 T 06-07-2017 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 BWK49_RS11790 4404935df1f03e813efab710e0d731c1 291 SUPERFAMILY SSF54506 65 281 2.43E-8 T 06-07-2017 BWK49_RS11790 4404935df1f03e813efab710e0d731c1 291 SUPERFAMILY SSF54506 1 136 1.96E-21 T 06-07-2017 BWK49_RS28470 92d0f64288f1b2515d63db6b3392d369 190 Pfam PF13384 Homeodomain-like domain 84 114 4.1E-6 T 06-07-2017 BWK49_RS28470 92d0f64288f1b2515d63db6b3392d369 190 Gene3D G3DSA:1.10.10.10 85 115 1.6E-4 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS03280 e07ec5676117cde77bc806da67635ba2 300 SUPERFAMILY SSF54593 1 123 3.95E-20 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS03280 e07ec5676117cde77bc806da67635ba2 300 ProSitePatterns PS00082 Extradiol ring-cleavage dioxygenases signature. 245 266 - T 06-07-2017 IPR000486 Extradiol ring-cleavage dioxygenase, class I /II GO:0003824|GO:0006725|GO:0008198|GO:0055114 BWK49_RS03280 e07ec5676117cde77bc806da67635ba2 300 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 142 267 3.2E-22 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain BWK49_RS03280 e07ec5676117cde77bc806da67635ba2 300 Gene3D G3DSA:3.10.180.10 134 295 3.6E-57 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS03280 e07ec5676117cde77bc806da67635ba2 300 SUPERFAMILY SSF54593 135 292 9.13E-36 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS03280 e07ec5676117cde77bc806da67635ba2 300 Gene3D G3DSA:3.10.180.10 1 131 4.6E-34 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS23555 d3ad08ae07bff5fe8e5f6f510fff31b6 404 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 309 365 9.0E-5 T 06-07-2017 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 BWK49_RS23555 d3ad08ae07bff5fe8e5f6f510fff31b6 404 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 7 247 7.4E-42 T 06-07-2017 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 BWK49_RS23555 d3ad08ae07bff5fe8e5f6f510fff31b6 404 SUPERFAMILY SSF51395 5 265 1.1E-86 T 06-07-2017 BWK49_RS23555 d3ad08ae07bff5fe8e5f6f510fff31b6 404 SUPERFAMILY SSF51395 300 388 1.1E-86 T 06-07-2017 BWK49_RS23555 d3ad08ae07bff5fe8e5f6f510fff31b6 404 Gene3D G3DSA:3.20.20.70 6 262 2.9E-92 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 BWK49_RS23555 d3ad08ae07bff5fe8e5f6f510fff31b6 404 Gene3D G3DSA:3.20.20.70 303 387 2.9E-92 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 BWK49_RS10650 3877f50dc19bd7adc6f4cbbcdc3a0c8b 68 Gene3D G3DSA:3.30.70.100 3 66 5.9E-20 T 06-07-2017 BWK49_RS10650 3877f50dc19bd7adc6f4cbbcdc3a0c8b 68 ProSitePatterns PS01047 Heavy-metal-associated domain. 8 37 - T 06-07-2017 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 BWK49_RS10650 3877f50dc19bd7adc6f4cbbcdc3a0c8b 68 SUPERFAMILY SSF55008 1 66 2.88E-17 T 06-07-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 BWK49_RS10650 3877f50dc19bd7adc6f4cbbcdc3a0c8b 68 PRINTS PR00944 Copper ion binding protein signature 53 66 2.6E-7 T 06-07-2017 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 BWK49_RS10650 3877f50dc19bd7adc6f4cbbcdc3a0c8b 68 PRINTS PR00944 Copper ion binding protein signature 3 15 2.6E-7 T 06-07-2017 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 BWK49_RS10650 3877f50dc19bd7adc6f4cbbcdc3a0c8b 68 PRINTS PR00944 Copper ion binding protein signature 15 28 2.6E-7 T 06-07-2017 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 BWK49_RS10650 3877f50dc19bd7adc6f4cbbcdc3a0c8b 68 PRINTS PR00944 Copper ion binding protein signature 28 41 2.6E-7 T 06-07-2017 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 BWK49_RS10650 3877f50dc19bd7adc6f4cbbcdc3a0c8b 68 Pfam PF00403 Heavy-metal-associated domain 5 65 4.7E-13 T 06-07-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 BWK49_RS16600 382b6c0f6e9f9154eb8e997392140d58 219 Gene3D G3DSA:3.40.50.300 1 212 1.3E-68 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS16600 382b6c0f6e9f9154eb8e997392140d58 219 SUPERFAMILY SSF52540 1 214 6.08E-38 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS16600 382b6c0f6e9f9154eb8e997392140d58 219 TIGRFAM TIGR00017 cmk: cytidylate kinase 2 205 5.2E-63 T 06-07-2017 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 BWK49_RS16600 382b6c0f6e9f9154eb8e997392140d58 219 Pfam PF02224 Cytidylate kinase 2 211 3.0E-78 T 06-07-2017 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 BWK49_RS16600 382b6c0f6e9f9154eb8e997392140d58 219 Hamap MF_00238 Cytidylate kinase [cmk]. 1 215 30.144 T 06-07-2017 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 BWK49_RS02425 072eebf1a101f53d484b6709755d1859 238 Gene3D G3DSA:3.40.50.1820 40 238 2.5E-57 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS02425 072eebf1a101f53d484b6709755d1859 238 Pfam PF01083 Cutinase 40 237 9.7E-48 T 06-07-2017 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 BWK49_RS02425 072eebf1a101f53d484b6709755d1859 238 SUPERFAMILY SSF53474 40 238 3.85E-44 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS02425 072eebf1a101f53d484b6709755d1859 238 SMART SM01110 39 238 2.2E-99 T 06-07-2017 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 BWK49_RS08190 f87f6355efdbec6a1b38a070eb8e571d 173 PIRSF PIRSF008502 1 173 7.4E-56 T 06-07-2017 IPR012545 Protein of unknown function DUF1697 BWK49_RS08190 f87f6355efdbec6a1b38a070eb8e571d 173 Gene3D G3DSA:3.30.70.1280 1 86 7.9E-28 T 06-07-2017 BWK49_RS08190 f87f6355efdbec6a1b38a070eb8e571d 173 Pfam PF08002 Protein of unknown function (DUF1697) 1 134 1.3E-38 T 06-07-2017 IPR012545 Protein of unknown function DUF1697 BWK49_RS08190 f87f6355efdbec6a1b38a070eb8e571d 173 SUPERFAMILY SSF160379 1 172 2.09E-49 T 06-07-2017 BWK49_RS08790 01b11043d086ba8ad9fcccf2a6afd677 325 Gene3D G3DSA:1.10.3720.10 89 320 4.4E-14 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS08790 01b11043d086ba8ad9fcccf2a6afd677 325 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 323 3.7E-37 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS08790 01b11043d086ba8ad9fcccf2a6afd677 325 SUPERFAMILY SSF161098 187 306 3.76E-16 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS08790 01b11043d086ba8ad9fcccf2a6afd677 325 SUPERFAMILY SSF161098 90 159 3.76E-16 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS18070 d44b9f0c9c2249d074c5e6a5da5d9cd7 935 Gene3D G3DSA:3.40.50.300 30 166 3.5E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS18070 d44b9f0c9c2249d074c5e6a5da5d9cd7 935 SMART SM00421 874 931 6.1E-22 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS18070 d44b9f0c9c2249d074c5e6a5da5d9cd7 935 Pfam PF13191 AAA ATPase domain 21 170 1.9E-17 T 06-07-2017 BWK49_RS18070 d44b9f0c9c2249d074c5e6a5da5d9cd7 935 ProSitePatterns PS00622 LuxR-type HTH domain signature. 891 918 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS18070 d44b9f0c9c2249d074c5e6a5da5d9cd7 935 Pfam PF00196 Bacterial regulatory proteins, luxR family 875 930 7.1E-17 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS18070 d44b9f0c9c2249d074c5e6a5da5d9cd7 935 SUPERFAMILY SSF46894 865 932 3.27E-18 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 BWK49_RS18070 d44b9f0c9c2249d074c5e6a5da5d9cd7 935 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 907 919 5.1E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS18070 d44b9f0c9c2249d074c5e6a5da5d9cd7 935 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 877 891 5.1E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS18070 d44b9f0c9c2249d074c5e6a5da5d9cd7 935 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 891 907 5.1E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 BWK49_RS18070 d44b9f0c9c2249d074c5e6a5da5d9cd7 935 Gene3D G3DSA:1.10.10.10 869 931 2.7E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS18070 d44b9f0c9c2249d074c5e6a5da5d9cd7 935 SUPERFAMILY SSF52540 16 245 4.15E-10 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS07465 cde22ed946cfcf1acd6a7b23fc3be03b 114 Pfam PF03960 ArsC family 7 113 4.1E-13 T 06-07-2017 IPR006660 Arsenate reductase-like BWK49_RS07465 cde22ed946cfcf1acd6a7b23fc3be03b 114 SUPERFAMILY SSF52833 5 114 5.04E-34 T 06-07-2017 IPR012336 Thioredoxin-like fold BWK49_RS07465 cde22ed946cfcf1acd6a7b23fc3be03b 114 TIGRFAM TIGR00014 arsC: arsenate reductase (glutaredoxin) 6 114 2.9E-42 T 06-07-2017 IPR006659 Arsenate reductase GO:0008794|GO:0055114 MetaCyc: PWY-4202|MetaCyc: PWY-4621 BWK49_RS07465 cde22ed946cfcf1acd6a7b23fc3be03b 114 Gene3D G3DSA:3.40.30.10 2 114 1.1E-46 T 06-07-2017 IPR012336 Thioredoxin-like fold BWK49_RS24820 3504d47042e72203f448e384beb34b11 341 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 8 326 35.988 T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 BWK49_RS24820 3504d47042e72203f448e384beb34b11 341 Gene3D G3DSA:1.10.1040.10 188 328 2.0E-51 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 BWK49_RS24820 3504d47042e72203f448e384beb34b11 341 SUPERFAMILY SSF51735 8 184 1.71E-42 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS24820 3504d47042e72203f448e384beb34b11 341 Gene3D G3DSA:3.40.50.720 4 187 4.6E-57 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS24820 3504d47042e72203f448e384beb34b11 341 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 184 324 4.1E-48 T 06-07-2017 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 BWK49_RS24820 3504d47042e72203f448e384beb34b11 341 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 9 164 3.1E-48 T 06-07-2017 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 BWK49_RS24820 3504d47042e72203f448e384beb34b11 341 PIRSF PIRSF000114 2 336 3.4E-105 T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 BWK49_RS24820 3504d47042e72203f448e384beb34b11 341 SUPERFAMILY SSF48179 183 335 3.4E-47 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 BWK49_RS24820 3504d47042e72203f448e384beb34b11 341 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 192 213 - T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 BWK49_RS24820 3504d47042e72203f448e384beb34b11 341 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 62 89 1.9E-45 T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 BWK49_RS24820 3504d47042e72203f448e384beb34b11 341 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 242 259 1.9E-45 T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 BWK49_RS24820 3504d47042e72203f448e384beb34b11 341 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 12 29 1.9E-45 T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 BWK49_RS24820 3504d47042e72203f448e384beb34b11 341 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 202 226 1.9E-45 T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 BWK49_RS24820 3504d47042e72203f448e384beb34b11 341 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 137 157 1.9E-45 T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 BWK49_RS24820 3504d47042e72203f448e384beb34b11 341 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 177 201 1.9E-45 T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 BWK49_RS27725 dea7c9b93d92635692e4c988eb77931c 578 Gene3D G3DSA:3.40.50.1220 202 355 1.8E-40 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain BWK49_RS27725 dea7c9b93d92635692e4c988eb77931c 578 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 211 340 8.1E-33 T 06-07-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 BWK49_RS27725 dea7c9b93d92635692e4c988eb77931c 578 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 416 550 1.0E-25 T 06-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 BWK49_RS27725 dea7c9b93d92635692e4c988eb77931c 578 SUPERFAMILY SSF52518 18 192 2.99E-46 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS27725 dea7c9b93d92635692e4c988eb77931c 578 TIGRFAM TIGR03254 oxalate_oxc: oxalyl-CoA decarboxylase 17 568 1.9E-285 T 06-07-2017 IPR017660 Oxalyl-CoA decarboxylase GO:0008949|GO:0030976|GO:0033611|GO:0046872 KEGG: 00630+4.1.1.8|MetaCyc: PWY-6695|MetaCyc: PWY-6696 BWK49_RS27725 dea7c9b93d92635692e4c988eb77931c 578 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 20 187 7.3E-46 T 06-07-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 BWK49_RS27725 dea7c9b93d92635692e4c988eb77931c 578 SUPERFAMILY SSF52467 172 370 2.25E-38 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain BWK49_RS27725 dea7c9b93d92635692e4c988eb77931c 578 Gene3D G3DSA:3.40.50.970 14 190 5.2E-50 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS27725 dea7c9b93d92635692e4c988eb77931c 578 Gene3D G3DSA:3.40.50.970 375 559 1.2E-51 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS27725 dea7c9b93d92635692e4c988eb77931c 578 SUPERFAMILY SSF52518 376 559 2.53E-41 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS20400 0c45cd6b981122038b21c4fcbdbbb7a3 282 SMART SM00898 2 118 5.6E-41 T 06-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 BWK49_RS20400 0c45cd6b981122038b21c4fcbdbbb7a3 282 SMART SM01232 137 229 5.5E-40 T 06-07-2017 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 BWK49_RS20400 0c45cd6b981122038b21c4fcbdbbb7a3 282 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 278 41.126 T 06-07-2017 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 BWK49_RS20400 0c45cd6b981122038b21c4fcbdbbb7a3 282 SUPERFAMILY SSF81624 2 146 1.02E-33 T 06-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 BWK49_RS20400 0c45cd6b981122038b21c4fcbdbbb7a3 282 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 137 224 2.2E-27 T 06-07-2017 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 BWK49_RS20400 0c45cd6b981122038b21c4fcbdbbb7a3 282 ProSitePatterns PS01242 Zinc finger FPG-type signature. 253 277 - T 06-07-2017 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 BWK49_RS20400 0c45cd6b981122038b21c4fcbdbbb7a3 282 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 277 5.9E-102 T 06-07-2017 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 BWK49_RS20400 0c45cd6b981122038b21c4fcbdbbb7a3 282 SUPERFAMILY SSF57716 229 278 6.27E-16 T 06-07-2017 BWK49_RS20400 0c45cd6b981122038b21c4fcbdbbb7a3 282 Gene3D G3DSA:1.10.8.50 138 278 2.7E-47 T 06-07-2017 BWK49_RS20400 0c45cd6b981122038b21c4fcbdbbb7a3 282 SUPERFAMILY SSF46946 136 226 1.03E-26 T 06-07-2017 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 BWK49_RS20400 0c45cd6b981122038b21c4fcbdbbb7a3 282 Gene3D G3DSA:3.20.190.10 2 124 9.1E-38 T 06-07-2017 BWK49_RS20400 0c45cd6b981122038b21c4fcbdbbb7a3 282 Pfam PF06827 Zinc finger found in FPG and IleRS 253 279 4.8E-8 T 06-07-2017 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 BWK49_RS20400 0c45cd6b981122038b21c4fcbdbbb7a3 282 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 117 8.2E-34 T 06-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 BWK49_RS19365 cbc4fb2324e5a649cb10042e474a3912 216 Gene3D G3DSA:3.30.70.1450 143 196 1.4E-4 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 BWK49_RS19365 cbc4fb2324e5a649cb10042e474a3912 216 SUPERFAMILY SSF116726 138 200 1.31E-5 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 BWK49_RS19365 cbc4fb2324e5a649cb10042e474a3912 216 Pfam PF02254 TrkA-N domain 1 111 4.3E-25 T 06-07-2017 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 BWK49_RS19365 cbc4fb2324e5a649cb10042e474a3912 216 SUPERFAMILY SSF51735 2 128 6.4E-26 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS19365 cbc4fb2324e5a649cb10042e474a3912 216 Gene3D G3DSA:3.40.50.720 1 127 2.8E-29 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS05830 8d7546000cbf0acbbe1292e023bcc7f7 301 SUPERFAMILY SSF56645 1 82 1.08E-5 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS05830 8d7546000cbf0acbbe1292e023bcc7f7 301 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 169 284 7.9E-17 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS05830 8d7546000cbf0acbbe1292e023bcc7f7 301 Gene3D G3DSA:1.20.140.10 168 282 2.8E-23 T 06-07-2017 BWK49_RS05830 8d7546000cbf0acbbe1292e023bcc7f7 301 SUPERFAMILY SSF47203 165 284 1.16E-27 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS27930 190d14e67f6e7e36aa678a6d08947579 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 61 72 1.5E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27930 190d14e67f6e7e36aa678a6d08947579 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 1.5E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27930 190d14e67f6e7e36aa678a6d08947579 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 1.5E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27930 190d14e67f6e7e36aa678a6d08947579 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 1.5E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27930 190d14e67f6e7e36aa678a6d08947579 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 1.5E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27930 190d14e67f6e7e36aa678a6d08947579 281 Gene3D G3DSA:3.40.50.720 4 254 5.6E-47 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS27930 190d14e67f6e7e36aa678a6d08947579 281 Pfam PF00106 short chain dehydrogenase 5 119 2.6E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27930 190d14e67f6e7e36aa678a6d08947579 281 SUPERFAMILY SSF51735 2 255 1.63E-44 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS27930 190d14e67f6e7e36aa678a6d08947579 281 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 155 252 1.3E-15 T 06-07-2017 BWK49_RS12780 d126b1bf2511cad8eff84572c7ebe184 305 Pfam PF08338 Domain of unknown function (DUF1731) 252 295 1.6E-14 T 06-07-2017 IPR013549 Domain of unknown function DUF1731 BWK49_RS12780 d126b1bf2511cad8eff84572c7ebe184 305 Gene3D G3DSA:3.40.50.720 8 248 3.5E-20 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS12780 d126b1bf2511cad8eff84572c7ebe184 305 TIGRFAM TIGR01777 yfcH: TIGR01777 family protein 8 295 1.4E-97 T 06-07-2017 IPR010099 Epimerase family protein SDR39U1 BWK49_RS12780 d126b1bf2511cad8eff84572c7ebe184 305 Pfam PF01370 NAD dependent epimerase/dehydratase family 9 215 5.9E-13 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 BWK49_RS12780 d126b1bf2511cad8eff84572c7ebe184 305 SUPERFAMILY SSF51735 7 255 1.75E-35 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS11625 12996b4818fe8d5a85c9a1beceda6594 484 PIRSF PIRSF006060 23 484 4.0E-87 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 BWK49_RS11625 12996b4818fe8d5a85c9a1beceda6594 484 Pfam PF13520 Amino acid permease 35 440 6.0E-52 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 BWK49_RS19505 faa925c99b8322bb3c30b8c86cf78df0 154 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 144 3.2E-47 T 06-07-2017 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 BWK49_RS19505 faa925c99b8322bb3c30b8c86cf78df0 154 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 151 78.062 T 06-07-2017 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 BWK49_RS19505 faa925c99b8322bb3c30b8c86cf78df0 154 Pfam PF03477 ATP cone domain 47 132 1.6E-13 T 06-07-2017 IPR005144 ATP-cone domain Reactome: R-HSA-499943 BWK49_RS14095 0b9d85ac22f74667d9919e960ff5eff1 252 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 104 246 1.7E-15 T 06-07-2017 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 BWK49_RS14095 0b9d85ac22f74667d9919e960ff5eff1 252 Gene3D G3DSA:1.10.357.10 29 251 5.9E-52 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS14095 0b9d85ac22f74667d9919e960ff5eff1 252 Pfam PF00440 Bacterial regulatory proteins, tetR family 41 83 4.4E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS14095 0b9d85ac22f74667d9919e960ff5eff1 252 SUPERFAMILY SSF46689 31 100 4.82E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS14095 0b9d85ac22f74667d9919e960ff5eff1 252 SUPERFAMILY SSF48498 103 249 1.85E-22 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS08235 d1ff132eaa407f69565a442819658482 94 Hamap MF_00434 Putative pterin-4-alpha-carbinolamine dehydratase. 1 92 20.514 T 06-07-2017 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 BWK49_RS08235 d1ff132eaa407f69565a442819658482 94 Gene3D G3DSA:3.30.1360.20 2 92 2.8E-26 T 06-07-2017 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 BWK49_RS08235 d1ff132eaa407f69565a442819658482 94 Pfam PF01329 Pterin 4 alpha carbinolamine dehydratase 4 90 2.5E-25 T 06-07-2017 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 BWK49_RS08235 d1ff132eaa407f69565a442819658482 94 SUPERFAMILY SSF55248 3 92 1.7E-28 T 06-07-2017 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 BWK49_RS03675 8351f33598ead2eab96d8ee4feb9c5a5 519 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 380 464 6.1E-10 T 06-07-2017 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain BWK49_RS03675 8351f33598ead2eab96d8ee4feb9c5a5 519 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 109 281 4.1E-43 T 06-07-2017 IPR004474 Cell envelope-related transcriptional attenuator domain BWK49_RS03675 8351f33598ead2eab96d8ee4feb9c5a5 519 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 109 280 6.3E-31 T 06-07-2017 IPR004474 Cell envelope-related transcriptional attenuator domain BWK49_RS13860 d4ab29df4baec4fe320e5a4476d6349d 366 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 186 3.4E-24 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 BWK49_RS13860 d4ab29df4baec4fe320e5a4476d6349d 366 Gene3D G3DSA:3.40.50.720 5 196 1.0E-38 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS13860 d4ab29df4baec4fe320e5a4476d6349d 366 SUPERFAMILY SSF51735 5 244 6.1E-44 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS17645 6e1466325a8e6666682be195f6b08a71 263 PIRSF PIRSF006648 2 260 7.9E-68 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 BWK49_RS17645 6e1466325a8e6666682be195f6b08a71 263 TIGRFAM TIGR01248 drrC: daunorubicin resistance protein C 76 227 3.9E-71 T 06-07-2017 IPR005943 Daunorubicin resistance protein C BWK49_RS17645 6e1466325a8e6666682be195f6b08a71 263 Pfam PF01061 ABC-2 type transporter 19 222 2.4E-16 T 06-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 BWK49_RS27180 e03d5e22f28912caffb41d8072e45827 337 TIGRFAM TIGR02960 SigX5: RNA polymerase sigma-70 factor, TIGR02960 family 16 328 7.9E-142 T 06-07-2017 IPR014305 RNA polymerase sigma-G type, actinobacteria BWK49_RS27180 e03d5e22f28912caffb41d8072e45827 337 Pfam PF12680 SnoaL-like domain 218 292 4.5E-7 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain BWK49_RS27180 e03d5e22f28912caffb41d8072e45827 337 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 45 76 - T 06-07-2017 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS27180 e03d5e22f28912caffb41d8072e45827 337 Gene3D G3DSA:1.10.10.10 139 195 1.9E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS27180 e03d5e22f28912caffb41d8072e45827 337 SUPERFAMILY SSF88659 140 194 5.05E-11 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS27180 e03d5e22f28912caffb41d8072e45827 337 Gene3D G3DSA:3.10.450.50 207 328 1.5E-22 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS27180 e03d5e22f28912caffb41d8072e45827 337 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 24 194 2.6E-23 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS27180 e03d5e22f28912caffb41d8072e45827 337 SUPERFAMILY SSF88946 20 93 3.34E-23 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS27180 e03d5e22f28912caffb41d8072e45827 337 Pfam PF04542 Sigma-70 region 2 25 90 4.3E-21 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS27180 e03d5e22f28912caffb41d8072e45827 337 Pfam PF08281 Sigma-70, region 4 142 194 2.0E-13 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS27180 e03d5e22f28912caffb41d8072e45827 337 Gene3D G3DSA:1.10.1740.10 20 99 9.9E-27 T 06-07-2017 BWK49_RS27180 e03d5e22f28912caffb41d8072e45827 337 SUPERFAMILY SSF54427 208 319 1.55E-17 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS24485 c21e8e76e30d8a3310b75cc4817cec3c 1316 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 10 1268 0.0 T 06-07-2017 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 BWK49_RS24485 c21e8e76e30d8a3310b75cc4817cec3c 1316 Gene3D G3DSA:2.40.40.20 424 451 1.8E-37 T 06-07-2017 BWK49_RS24485 c21e8e76e30d8a3310b75cc4817cec3c 1316 Gene3D G3DSA:2.40.40.20 492 564 1.8E-37 T 06-07-2017 BWK49_RS24485 c21e8e76e30d8a3310b75cc4817cec3c 1316 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 5 1277 9.921 T 06-07-2017 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 BWK49_RS24485 c21e8e76e30d8a3310b75cc4817cec3c 1316 Pfam PF04997 RNA polymerase Rpb1, domain 1 7 417 2.1E-82 T 06-07-2017 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 BWK49_RS24485 c21e8e76e30d8a3310b75cc4817cec3c 1316 SUPERFAMILY SSF64484 5 1269 0.0 T 06-07-2017 BWK49_RS24485 c21e8e76e30d8a3310b75cc4817cec3c 1316 Pfam PF04998 RNA polymerase Rpb1, domain 5 843 1216 1.7E-64 T 06-07-2017 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 BWK49_RS24485 c21e8e76e30d8a3310b75cc4817cec3c 1316 Pfam PF04983 RNA polymerase Rpb1, domain 3 564 736 5.0E-27 T 06-07-2017 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 BWK49_RS24485 c21e8e76e30d8a3310b75cc4817cec3c 1316 Pfam PF00623 RNA polymerase Rpb1, domain 2 419 560 1.6E-35 T 06-07-2017 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 BWK49_RS24485 c21e8e76e30d8a3310b75cc4817cec3c 1316 SMART SM00663 310 589 5.8E-173 T 06-07-2017 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 BWK49_RS24485 c21e8e76e30d8a3310b75cc4817cec3c 1316 Pfam PF05000 RNA polymerase Rpb1, domain 4 752 828 6.2E-8 T 06-07-2017 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 BWK49_RS12465 6f6fb02d06124a145f71ee88654043a2 302 SUPERFAMILY SSF55048 129 183 1.83E-11 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 BWK49_RS12465 6f6fb02d06124a145f71ee88654043a2 302 SUPERFAMILY SSF52151 183 301 7.32E-59 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 BWK49_RS12465 6f6fb02d06124a145f71ee88654043a2 302 SUPERFAMILY SSF52151 2 121 7.32E-59 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 BWK49_RS12465 6f6fb02d06124a145f71ee88654043a2 302 Pfam PF00698 Acyl transferase domain 7 284 1.0E-21 T 06-07-2017 IPR014043 Acyl transferase BWK49_RS12465 6f6fb02d06124a145f71ee88654043a2 302 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 5 293 1.2E-13 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain BWK49_RS12465 6f6fb02d06124a145f71ee88654043a2 302 Gene3D G3DSA:3.30.70.250 124 189 5.5E-21 T 06-07-2017 BWK49_RS12465 6f6fb02d06124a145f71ee88654043a2 302 Gene3D G3DSA:3.40.366.10 2 121 7.8E-46 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 BWK49_RS12465 6f6fb02d06124a145f71ee88654043a2 302 Gene3D G3DSA:3.40.366.10 190 295 7.8E-46 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 BWK49_RS27140 6e091475fed61b5bab9da36995edb3d2 146 Pfam PF03779 SPW repeat 35 80 1.9E-15 T 06-07-2017 IPR005530 SPW repeat BWK49_RS27140 6e091475fed61b5bab9da36995edb3d2 146 Pfam PF03779 SPW repeat 88 134 6.0E-15 T 06-07-2017 IPR005530 SPW repeat BWK49_RS19260 21dcd288c72d5b36158c6b4cc299f852 377 Gene3D G3DSA:3.40.50.300 38 238 5.9E-21 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS19260 21dcd288c72d5b36158c6b4cc299f852 377 Pfam PF03969 AFG1-like ATPase 34 254 8.1E-61 T 06-07-2017 IPR005654 ATPase, AFG1-like GO:0005524 BWK49_RS19260 21dcd288c72d5b36158c6b4cc299f852 377 SUPERFAMILY SSF52540 96 219 9.66E-8 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS25285 bdac1eb88ddb102df8d1d69c7bb15d73 831 PRINTS PR01217 Proline rich extensin signature 492 513 7.1E-9 T 06-07-2017 BWK49_RS25285 bdac1eb88ddb102df8d1d69c7bb15d73 831 PRINTS PR01217 Proline rich extensin signature 531 548 7.1E-9 T 06-07-2017 BWK49_RS25285 bdac1eb88ddb102df8d1d69c7bb15d73 831 PRINTS PR01217 Proline rich extensin signature 513 529 7.1E-9 T 06-07-2017 BWK49_RS25285 bdac1eb88ddb102df8d1d69c7bb15d73 831 PRINTS PR01217 Proline rich extensin signature 460 476 7.1E-9 T 06-07-2017 BWK49_RS25285 bdac1eb88ddb102df8d1d69c7bb15d73 831 PRINTS PR01217 Proline rich extensin signature 578 603 7.1E-9 T 06-07-2017 BWK49_RS25285 bdac1eb88ddb102df8d1d69c7bb15d73 831 PRINTS PR01217 Proline rich extensin signature 446 458 7.1E-9 T 06-07-2017 BWK49_RS25285 bdac1eb88ddb102df8d1d69c7bb15d73 831 Pfam PF14021 Protein of unknown function (DUF4237) 732 830 1.7E-13 T 06-07-2017 IPR025331 Protein of unknown function DUF4237 BWK49_RS08745 52c766f9c26225698ef99c133bb0a59a 185 Pfam PF12079 Protein of unknown function (DUF3558) 21 183 5.2E-38 T 06-07-2017 IPR024520 Protein of unknown function DUF3558 BWK49_RS08745 52c766f9c26225698ef99c133bb0a59a 185 ProDom PD103646 LIPOPROTEIN LPRB MEMBRANE PRECURSOR PALMITATE SIGNAL 18 185 3.0E-90 T 06-07-2017 BWK49_RS18645 cd26293f9479d0d83d3727966eaeaf97 454 SUPERFAMILY SSF48019 262 445 6.8E-73 T 06-07-2017 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 BWK49_RS18645 cd26293f9479d0d83d3727966eaeaf97 454 Pfam PF12002 MgsA AAA+ ATPase C terminal 277 442 2.3E-68 T 06-07-2017 IPR021886 MgsA AAA+ ATPase C-terminal BWK49_RS18645 cd26293f9479d0d83d3727966eaeaf97 454 Pfam PF16193 AAA C-terminal domain 202 276 1.3E-26 T 06-07-2017 IPR032423 AAA ATPase, C-terminal domain BWK49_RS18645 cd26293f9479d0d83d3727966eaeaf97 454 SMART SM00382 64 180 2.7E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS18645 cd26293f9479d0d83d3727966eaeaf97 454 Gene3D G3DSA:1.10.3710.10 357 450 9.1E-28 T 06-07-2017 BWK49_RS18645 cd26293f9479d0d83d3727966eaeaf97 454 Gene3D G3DSA:3.40.50.300 29 167 9.0E-31 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS18645 cd26293f9479d0d83d3727966eaeaf97 454 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 69 164 1.1E-13 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 BWK49_RS18645 cd26293f9479d0d83d3727966eaeaf97 454 Gene3D G3DSA:1.10.8.60 168 248 2.2E-9 T 06-07-2017 BWK49_RS18645 cd26293f9479d0d83d3727966eaeaf97 454 SUPERFAMILY SSF52540 26 247 1.11E-38 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS18645 cd26293f9479d0d83d3727966eaeaf97 454 Gene3D G3DSA:1.20.272.10 258 356 3.1E-46 T 06-07-2017 BWK49_RS24455 b4f48dbcf310b287e3a923a96165dbd0 255 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 97 117 - T 06-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 BWK49_RS24455 b4f48dbcf310b287e3a923a96165dbd0 255 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 241 1.0E-40 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 BWK49_RS24455 b4f48dbcf310b287e3a923a96165dbd0 255 Gene3D G3DSA:3.90.226.10 3 244 7.8E-69 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS24455 b4f48dbcf310b287e3a923a96165dbd0 255 SUPERFAMILY SSF52096 4 230 2.87E-65 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS20745 c2e295add76f53e1cadd4c99e44ae17e 255 Gene3D G3DSA:3.40.30.10 73 238 2.8E-19 T 06-07-2017 IPR012336 Thioredoxin-like fold BWK49_RS20745 c2e295add76f53e1cadd4c99e44ae17e 255 SUPERFAMILY SSF52833 72 236 7.35E-18 T 06-07-2017 IPR012336 Thioredoxin-like fold BWK49_RS20745 c2e295add76f53e1cadd4c99e44ae17e 255 Pfam PF13462 Thioredoxin 73 237 1.1E-22 T 06-07-2017 IPR012336 Thioredoxin-like fold BWK49_RS11195 ebcac38cf60a760db006d1ac0e577f7b 377 SMART SM00922 156 248 2.4E-20 T 06-07-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal BWK49_RS11195 ebcac38cf60a760db006d1ac0e577f7b 377 Gene3D G3DSA:3.30.390.10 12 143 3.3E-39 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 BWK49_RS11195 ebcac38cf60a760db006d1ac0e577f7b 377 SUPERFAMILY SSF51604 126 374 2.1E-59 T 06-07-2017 IPR029065 Enolase C-terminal domain-like BWK49_RS11195 ebcac38cf60a760db006d1ac0e577f7b 377 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 42 138 8.6E-18 T 06-07-2017 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain BWK49_RS11195 ebcac38cf60a760db006d1ac0e577f7b 377 SUPERFAMILY SSF54826 12 139 3.7E-29 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 BWK49_RS11195 ebcac38cf60a760db006d1ac0e577f7b 377 Gene3D G3DSA:3.20.20.120 144 373 9.0E-58 T 06-07-2017 IPR029065 Enolase C-terminal domain-like BWK49_RS11195 ebcac38cf60a760db006d1ac0e577f7b 377 Pfam PF13378 Enolase C-terminal domain-like 164 366 7.7E-49 T 06-07-2017 IPR029065 Enolase C-terminal domain-like BWK49_RS26405 1393d30cbefd84e3e0e8b2fceabb1b1f 395 SUPERFAMILY SSF53474 150 393 1.3E-33 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS26405 1393d30cbefd84e3e0e8b2fceabb1b1f 395 Gene3D G3DSA:3.40.50.1820 153 393 3.4E-36 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS26405 1393d30cbefd84e3e0e8b2fceabb1b1f 395 Pfam PF00326 Prolyl oligopeptidase family 236 393 5.6E-7 T 06-07-2017 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 BWK49_RS23960 0d9054455838a18f917582c548d92a1d 1229 TIGRFAM TIGR03925 T7SS_EccC_b: type VII secretion protein EccCb 685 1225 3.3E-223 T 06-07-2017 IPR023837 EccCb-like, Actinobacteria BWK49_RS23960 0d9054455838a18f917582c548d92a1d 1229 SMART SM00382 419 600 1.8 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS23960 0d9054455838a18f917582c548d92a1d 1229 SMART SM00382 1021 1180 3.6 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS23960 0d9054455838a18f917582c548d92a1d 1229 SMART SM00382 754 926 2.4 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS23960 0d9054455838a18f917582c548d92a1d 1229 SUPERFAMILY SSF52540 380 634 4.26E-27 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS23960 0d9054455838a18f917582c548d92a1d 1229 Gene3D G3DSA:3.40.50.300 1004 1073 1.4E-4 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS23960 0d9054455838a18f917582c548d92a1d 1229 Gene3D G3DSA:3.40.50.300 372 640 1.2E-24 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS23960 0d9054455838a18f917582c548d92a1d 1229 Gene3D G3DSA:3.40.50.300 746 936 4.9E-12 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS23960 0d9054455838a18f917582c548d92a1d 1229 SUPERFAMILY SSF52540 702 956 7.71E-24 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS23960 0d9054455838a18f917582c548d92a1d 1229 SUPERFAMILY SSF52540 978 1159 2.77E-9 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS23960 0d9054455838a18f917582c548d92a1d 1229 Pfam PF01580 FtsK/SpoIIIE family 731 965 6.3E-59 T 06-07-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 BWK49_RS23960 0d9054455838a18f917582c548d92a1d 1229 Pfam PF01580 FtsK/SpoIIIE family 388 520 1.4E-24 T 06-07-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 BWK49_RS10680 57ba91c8a19091ea388720b4cdeda3e1 97 SUPERFAMILY SSF140459 8 84 3.14E-18 T 06-07-2017 BWK49_RS10680 57ba91c8a19091ea388720b4cdeda3e1 97 Pfam PF00934 PE family 1 93 1.3E-26 T 06-07-2017 IPR000084 PE-PGRS family, N-terminal BWK49_RS10745 3b332f061d1c6b471c7714bc712861c8 122 Pfam PF05305 Protein of unknown function (DUF732) 16 107 4.1E-24 T 06-07-2017 IPR007969 Domain of unknown function DUF732 BWK49_RS10730 85a7e5375147a0662aeaf9f8fe1557a4 364 Gene3D G3DSA:3.30.70.1350 267 348 3.6E-18 T 06-07-2017 IPR027470 Cation efflux protein, cytoplasmic domain BWK49_RS10730 85a7e5375147a0662aeaf9f8fe1557a4 364 Pfam PF16916 Dimerisation domain of Zinc Transporter 270 346 4.4E-15 T 06-07-2017 IPR027470 Cation efflux protein, cytoplasmic domain BWK49_RS10730 85a7e5375147a0662aeaf9f8fe1557a4 364 SUPERFAMILY SSF161111 70 267 4.71E-48 T 06-07-2017 BWK49_RS10730 85a7e5375147a0662aeaf9f8fe1557a4 364 SUPERFAMILY SSF160240 269 348 1.11E-16 T 06-07-2017 BWK49_RS10730 85a7e5375147a0662aeaf9f8fe1557a4 364 Pfam PF01545 Cation efflux family 74 265 4.5E-41 T 06-07-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 BWK49_RS10730 85a7e5375147a0662aeaf9f8fe1557a4 364 Gene3D G3DSA:1.20.1510.10 72 265 2.7E-41 T 06-07-2017 IPR027469 Cation efflux protein transmembrane domain BWK49_RS10730 85a7e5375147a0662aeaf9f8fe1557a4 364 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 73 347 1.2E-70 T 06-07-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 BWK49_RS04490 ee913172b7af1f1dd570a5ac28673ffe 601 SUPERFAMILY SSF48452 23 46 1.0E-5 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 BWK49_RS04490 ee913172b7af1f1dd570a5ac28673ffe 601 SUPERFAMILY SSF48452 106 124 1.0E-5 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 BWK49_RS04490 ee913172b7af1f1dd570a5ac28673ffe 601 SUPERFAMILY SSF48452 172 245 1.0E-5 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 BWK49_RS04490 ee913172b7af1f1dd570a5ac28673ffe 601 Gene3D G3DSA:1.25.40.10 22 50 1.8E-8 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 BWK49_RS04490 ee913172b7af1f1dd570a5ac28673ffe 601 Gene3D G3DSA:1.25.40.10 110 245 1.8E-8 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 BWK49_RS04490 ee913172b7af1f1dd570a5ac28673ffe 601 Gene3D G3DSA:3.40.50.300 309 501 9.0E-22 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS04490 ee913172b7af1f1dd570a5ac28673ffe 601 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 353 484 3.7E-14 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 BWK49_RS04490 ee913172b7af1f1dd570a5ac28673ffe 601 PRINTS PR00819 CbxX/CfqX superfamily signature 456 473 6.9E-35 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 BWK49_RS04490 ee913172b7af1f1dd570a5ac28673ffe 601 PRINTS PR00819 CbxX/CfqX superfamily signature 435 447 6.9E-35 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 BWK49_RS04490 ee913172b7af1f1dd570a5ac28673ffe 601 PRINTS PR00819 CbxX/CfqX superfamily signature 542 554 6.9E-35 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 BWK49_RS04490 ee913172b7af1f1dd570a5ac28673ffe 601 PRINTS PR00819 CbxX/CfqX superfamily signature 404 423 6.9E-35 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 BWK49_RS04490 ee913172b7af1f1dd570a5ac28673ffe 601 PRINTS PR00819 CbxX/CfqX superfamily signature 311 325 6.9E-35 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 BWK49_RS04490 ee913172b7af1f1dd570a5ac28673ffe 601 PRINTS PR00819 CbxX/CfqX superfamily signature 390 404 6.9E-35 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 BWK49_RS04490 ee913172b7af1f1dd570a5ac28673ffe 601 PRINTS PR00819 CbxX/CfqX superfamily signature 473 492 6.9E-35 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 BWK49_RS04490 ee913172b7af1f1dd570a5ac28673ffe 601 PRINTS PR00819 CbxX/CfqX superfamily signature 352 367 6.9E-35 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 BWK49_RS04490 ee913172b7af1f1dd570a5ac28673ffe 601 SUPERFAMILY SSF52540 306 594 9.08E-28 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS25355 894d58c87af3dfae00b1c74463420a1d 267 ProDom PD040376 SCO3349 RV0495C/MT0515 ML2435 MB0506C CGL0407 17 262 1.0E-130 T 06-07-2017 BWK49_RS10060 cc1cceca51a983a189db38c2d6e1e5a8 482 PIRSF PIRSF010256 1 482 1.3E-135 T 06-07-2017 IPR011195 Uncharacterised conserved protein UCP010256 BWK49_RS10060 cc1cceca51a983a189db38c2d6e1e5a8 482 SUPERFAMILY SSF53300 311 421 3.48E-5 T 06-07-2017 IPR002035 von Willebrand factor, type A BWK49_RS10060 cc1cceca51a983a189db38c2d6e1e5a8 482 Pfam PF05762 VWA domain containing CoxE-like protein 255 475 3.8E-61 T 06-07-2017 IPR008912 Uncharacterised protein family CoxE-like BWK49_RS21895 91b371f22dcfc73b85bb9749ad9622b6 265 Pfam PF01145 SPFH domain / Band 7 family 27 195 3.3E-34 T 06-07-2017 IPR001107 Band 7 domain BWK49_RS21895 91b371f22dcfc73b85bb9749ad9622b6 265 PRINTS PR00721 Stomatin signature 29 51 1.3E-63 T 06-07-2017 IPR001972 Stomatin family GO:0016020 BWK49_RS21895 91b371f22dcfc73b85bb9749ad9622b6 265 PRINTS PR00721 Stomatin signature 131 154 1.3E-63 T 06-07-2017 IPR001972 Stomatin family GO:0016020 BWK49_RS21895 91b371f22dcfc73b85bb9749ad9622b6 265 PRINTS PR00721 Stomatin signature 155 173 1.3E-63 T 06-07-2017 IPR001972 Stomatin family GO:0016020 BWK49_RS21895 91b371f22dcfc73b85bb9749ad9622b6 265 PRINTS PR00721 Stomatin signature 111 128 1.3E-63 T 06-07-2017 IPR001972 Stomatin family GO:0016020 BWK49_RS21895 91b371f22dcfc73b85bb9749ad9622b6 265 PRINTS PR00721 Stomatin signature 174 195 1.3E-63 T 06-07-2017 IPR001972 Stomatin family GO:0016020 BWK49_RS21895 91b371f22dcfc73b85bb9749ad9622b6 265 PRINTS PR00721 Stomatin signature 199 222 1.3E-63 T 06-07-2017 IPR001972 Stomatin family GO:0016020 BWK49_RS21895 91b371f22dcfc73b85bb9749ad9622b6 265 PRINTS PR00721 Stomatin signature 76 97 1.3E-63 T 06-07-2017 IPR001972 Stomatin family GO:0016020 BWK49_RS21895 91b371f22dcfc73b85bb9749ad9622b6 265 SMART SM00244 22 179 4.4E-51 T 06-07-2017 IPR001107 Band 7 domain BWK49_RS21895 91b371f22dcfc73b85bb9749ad9622b6 265 SUPERFAMILY SSF117892 53 186 6.8E-40 T 06-07-2017 IPR001107 Band 7 domain BWK49_RS09580 dde5e1721aed2648196822b23843d3ae 451 SUPERFAMILY SSF159245 10 370 2.09E-41 T 06-07-2017 BWK49_RS09580 dde5e1721aed2648196822b23843d3ae 451 Gene3D G3DSA:2.40.370.10 21 222 4.1E-21 T 06-07-2017 IPR023374 AttH-like domain BWK49_RS08025 9fbd762d041ff8efc0f449586d8911c5 498 Gene3D G3DSA:3.30.70.1450 410 470 1.6E-8 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 BWK49_RS08025 9fbd762d041ff8efc0f449586d8911c5 498 Pfam PF00999 Sodium/hydrogen exchanger family 15 382 9.8E-48 T 06-07-2017 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 BWK49_RS08025 9fbd762d041ff8efc0f449586d8911c5 498 Pfam PF02080 TrkA-C domain 414 470 4.1E-11 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 BWK49_RS08025 9fbd762d041ff8efc0f449586d8911c5 498 SUPERFAMILY SSF116726 408 473 1.7E-11 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 BWK49_RS13545 618e86538a852dd9da3a64cffb902792 516 SUPERFAMILY SSF56524 216 410 3.4E-51 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 BWK49_RS13545 618e86538a852dd9da3a64cffb902792 516 SUPERFAMILY SSF81296 403 513 2.1E-24 T 06-07-2017 IPR014756 Immunoglobulin E-set BWK49_RS13545 618e86538a852dd9da3a64cffb902792 516 Gene3D G3DSA:3.90.420.10 209 407 2.4E-49 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 BWK49_RS13545 618e86538a852dd9da3a64cffb902792 516 Pfam PF00174 Oxidoreductase molybdopterin binding domain 240 387 6.4E-35 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 BWK49_RS13545 618e86538a852dd9da3a64cffb902792 516 Gene3D G3DSA:2.60.40.650 408 513 4.0E-23 T 06-07-2017 IPR005066 Moybdenum cofactor oxidoreductase, dimerisation GO:0016491|GO:0030151|GO:0055114 Reactome: R-HSA-1614517 BWK49_RS13545 618e86538a852dd9da3a64cffb902792 516 PRINTS PR00407 Eukaryotic molybdopterin domain signature 290 305 1.0E-4 T 06-07-2017 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 BWK49_RS13545 618e86538a852dd9da3a64cffb902792 516 PRINTS PR00407 Eukaryotic molybdopterin domain signature 353 366 1.0E-4 T 06-07-2017 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 BWK49_RS07200 6ed198442e89e1c442c62162462fa912 377 PIRSF PIRSF001123 7 377 4.0E-34 T 06-07-2017 IPR008007 Peptidase M42 BWK49_RS07200 6ed198442e89e1c442c62162462fa912 377 SUPERFAMILY SSF53187 11 102 2.9E-40 T 06-07-2017 BWK49_RS07200 6ed198442e89e1c442c62162462fa912 377 SUPERFAMILY SSF53187 202 373 2.9E-40 T 06-07-2017 BWK49_RS07200 6ed198442e89e1c442c62162462fa912 377 Gene3D G3DSA:3.40.630.10 202 371 1.4E-52 T 06-07-2017 BWK49_RS07200 6ed198442e89e1c442c62162462fa912 377 Gene3D G3DSA:3.40.630.10 11 97 1.4E-52 T 06-07-2017 BWK49_RS07200 6ed198442e89e1c442c62162462fa912 377 Pfam PF05343 M42 glutamyl aminopeptidase 81 362 6.3E-42 T 06-07-2017 IPR008007 Peptidase M42 BWK49_RS07200 6ed198442e89e1c442c62162462fa912 377 Gene3D G3DSA:2.40.30.40 98 191 3.9E-14 T 06-07-2017 IPR023367 Peptidase M42, domain 2 BWK49_RS07200 6ed198442e89e1c442c62162462fa912 377 SUPERFAMILY SSF101821 93 210 1.36E-12 T 06-07-2017 BWK49_RS13150 dd12847d14aff01b4d50e806f5341e98 451 SUPERFAMILY SSF55031 300 335 7.96E-10 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain BWK49_RS13150 dd12847d14aff01b4d50e806f5341e98 451 SUPERFAMILY SSF55031 212 254 7.96E-10 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain BWK49_RS13150 dd12847d14aff01b4d50e806f5341e98 451 Pfam PF01546 Peptidase family M20/M25/M40 88 449 2.7E-37 T 06-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 BWK49_RS13150 dd12847d14aff01b4d50e806f5341e98 451 SUPERFAMILY SSF53187 15 197 3.67E-57 T 06-07-2017 BWK49_RS13150 dd12847d14aff01b4d50e806f5341e98 451 SUPERFAMILY SSF53187 361 450 3.67E-57 T 06-07-2017 BWK49_RS13150 dd12847d14aff01b4d50e806f5341e98 451 Gene3D G3DSA:3.40.630.10 386 449 1.7E-59 T 06-07-2017 BWK49_RS13150 dd12847d14aff01b4d50e806f5341e98 451 Gene3D G3DSA:3.40.630.10 16 221 1.7E-59 T 06-07-2017 BWK49_RS13150 dd12847d14aff01b4d50e806f5341e98 451 Gene3D G3DSA:3.30.70.360 222 262 4.2E-22 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain BWK49_RS13150 dd12847d14aff01b4d50e806f5341e98 451 Gene3D G3DSA:3.30.70.360 301 346 4.2E-22 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain BWK49_RS13150 dd12847d14aff01b4d50e806f5341e98 451 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 87 96 - T 06-07-2017 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 BWK49_RS13150 dd12847d14aff01b4d50e806f5341e98 451 Pfam PF07687 Peptidase dimerisation domain 209 346 8.1E-15 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain BWK49_RS27625 67995636fb275a8fd2ace65ffefce19a 151 Pfam PF01575 MaoC like domain 12 131 4.5E-32 T 06-07-2017 IPR002539 MaoC-like domain BWK49_RS27625 67995636fb275a8fd2ace65ffefce19a 151 Gene3D G3DSA:3.10.129.10 7 148 9.3E-39 T 06-07-2017 IPR029069 HotDog domain BWK49_RS27625 67995636fb275a8fd2ace65ffefce19a 151 SUPERFAMILY SSF54637 3 148 1.66E-41 T 06-07-2017 IPR029069 HotDog domain BWK49_RS08210 8348b1b9c3943b26f3ab0b1a3ed7b356 190 Gene3D G3DSA:1.10.340.30 15 134 1.9E-10 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 BWK49_RS08210 8348b1b9c3943b26f3ab0b1a3ed7b356 190 TIGRFAM TIGR03252 TIGR03252: uncharacterized HhH-GPD family protein 3 190 2.7E-98 T 06-07-2017 IPR017658 Conserved hypothetical protein CHP03252, HhH-GPD BWK49_RS08210 8348b1b9c3943b26f3ab0b1a3ed7b356 190 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 24 187 3.6E-21 T 06-07-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 BWK49_RS08210 8348b1b9c3943b26f3ab0b1a3ed7b356 190 SUPERFAMILY SSF48150 11 141 1.5E-12 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 BWK49_RS19285 773b1ec245fade3983e7d1a671413724 250 Pfam PF13649 Methyltransferase domain 54 149 7.0E-17 T 06-07-2017 BWK49_RS19285 773b1ec245fade3983e7d1a671413724 250 Gene3D G3DSA:3.40.50.150 31 194 1.4E-33 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS19285 773b1ec245fade3983e7d1a671413724 250 SUPERFAMILY SSF53335 6 196 7.0E-37 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS12850 810f6c79a8ead7e25aaf97e1ef5f0667 118 Pfam PF01521 Iron-sulphur cluster biosynthesis 16 115 7.2E-17 T 06-07-2017 IPR000361 FeS cluster biogenesis BWK49_RS12850 810f6c79a8ead7e25aaf97e1ef5f0667 118 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 14 118 1.1E-34 T 06-07-2017 IPR016092 FeS cluster insertion protein GO:0005198|GO:0016226|GO:0051536 BWK49_RS12850 810f6c79a8ead7e25aaf97e1ef5f0667 118 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 100 117 - T 06-07-2017 IPR017870 FeS cluster insertion, C-terminal, conserved site BWK49_RS12850 810f6c79a8ead7e25aaf97e1ef5f0667 118 SUPERFAMILY SSF89360 10 105 1.63E-27 T 06-07-2017 IPR000361 FeS cluster biogenesis BWK49_RS12850 810f6c79a8ead7e25aaf97e1ef5f0667 118 Gene3D G3DSA:2.60.300.12 14 107 3.7E-27 T 06-07-2017 IPR000361 FeS cluster biogenesis BWK49_RS22530 b2b8f2652f81ad5b7d154d0adae750d8 471 Gene3D G3DSA:3.50.50.60 301 377 3.3E-19 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS22530 b2b8f2652f81ad5b7d154d0adae750d8 471 Gene3D G3DSA:3.50.50.60 9 204 3.3E-19 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS22530 b2b8f2652f81ad5b7d154d0adae750d8 471 SUPERFAMILY SSF51905 311 384 8.19E-30 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS22530 b2b8f2652f81ad5b7d154d0adae750d8 471 SUPERFAMILY SSF51905 8 205 8.19E-30 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS21200 fbea2e14bf4d7c02fe0ca27a26f7ec0a 416 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 294 386 2.5E-9 T 06-07-2017 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 BWK49_RS21200 fbea2e14bf4d7c02fe0ca27a26f7ec0a 416 TIGRFAM TIGR01426 MGT: glycosyltransferase, MGT family 10 405 1.8E-42 T 06-07-2017 IPR006326 UDP-glycosyltransferase, MGT GO:0016758|GO:0016999 BWK49_RS21200 fbea2e14bf4d7c02fe0ca27a26f7ec0a 416 Gene3D G3DSA:3.40.50.2000 245 387 2.5E-29 T 06-07-2017 BWK49_RS21200 fbea2e14bf4d7c02fe0ca27a26f7ec0a 416 SUPERFAMILY SSF53756 4 405 1.76E-70 T 06-07-2017 BWK49_RS21200 fbea2e14bf4d7c02fe0ca27a26f7ec0a 416 Gene3D G3DSA:3.40.50.2000 3 244 1.6E-15 T 06-07-2017 BWK49_RS13040 c73b86f14cebd568c82e8f011e8a52ae 325 SUPERFAMILY SSF81799 119 220 6.28E-34 T 06-07-2017 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 BWK49_RS13040 c73b86f14cebd568c82e8f011e8a52ae 325 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 26 314 4.4E-83 T 06-07-2017 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 BWK49_RS13040 c73b86f14cebd568c82e8f011e8a52ae 325 Pfam PF01795 MraW methylase family 1 314 1.3E-110 T 06-07-2017 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 BWK49_RS13040 c73b86f14cebd568c82e8f011e8a52ae 325 Gene3D G3DSA:3.40.50.150 2 115 4.3E-40 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS13040 c73b86f14cebd568c82e8f011e8a52ae 325 Gene3D G3DSA:3.40.50.150 223 316 4.3E-40 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS13040 c73b86f14cebd568c82e8f011e8a52ae 325 SUPERFAMILY SSF53335 220 315 1.51E-34 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS13040 c73b86f14cebd568c82e8f011e8a52ae 325 SUPERFAMILY SSF53335 2 118 1.51E-34 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS13040 c73b86f14cebd568c82e8f011e8a52ae 325 PIRSF PIRSF004486 1 316 4.3E-94 T 06-07-2017 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 BWK49_RS13040 c73b86f14cebd568c82e8f011e8a52ae 325 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 1 315 34.629 T 06-07-2017 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 BWK49_RS13040 c73b86f14cebd568c82e8f011e8a52ae 325 Gene3D G3DSA:1.10.150.170 117 222 3.3E-37 T 06-07-2017 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 BWK49_RS27565 f2e76df08efd108afeac0894f8dd5013 370 SUPERFAMILY SSF160935 182 347 2.22E-7 T 06-07-2017 BWK49_RS27565 f2e76df08efd108afeac0894f8dd5013 370 Pfam PF06742 Protein of unknown function (DUF1214) 271 344 4.5E-4 T 06-07-2017 IPR010621 Domain of unknown function DUF1214 BWK49_RS27565 f2e76df08efd108afeac0894f8dd5013 370 Pfam PF06742 Protein of unknown function (DUF1214) 90 152 0.016 T 06-07-2017 IPR010621 Domain of unknown function DUF1214 BWK49_RS02880 6093da0b0aa98075f5d793a87e974f92 350 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 118 270 2.3E-7 T 06-07-2017 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain BWK49_RS02880 6093da0b0aa98075f5d793a87e974f92 350 Gene3D G3DSA:3.40.50.300 115 318 2.7E-20 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS02880 6093da0b0aa98075f5d793a87e974f92 350 SUPERFAMILY SSF52540 115 319 2.7E-21 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS02880 6093da0b0aa98075f5d793a87e974f92 350 TIGRFAM TIGR03815 CpaE_hom_Actino: helicase/secretion neighborhood CpaE-like protein 3 338 1.6E-109 T 06-07-2017 IPR022521 Conserved hypothetical protein CHP03815, CpaE-like BWK49_RS17055 8c44ee0d39ea7cb0e9d49b00df2be89c 456 Pfam PF00067 Cytochrome P450 20 434 4.7E-64 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS17055 8c44ee0d39ea7cb0e9d49b00df2be89c 456 PRINTS PR00465 E-class P450 group IV signature 364 382 2.7E-13 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS17055 8c44ee0d39ea7cb0e9d49b00df2be89c 456 PRINTS PR00465 E-class P450 group IV signature 315 331 2.7E-13 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS17055 8c44ee0d39ea7cb0e9d49b00df2be89c 456 PRINTS PR00465 E-class P450 group IV signature 404 422 2.7E-13 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS17055 8c44ee0d39ea7cb0e9d49b00df2be89c 456 PRINTS PR00465 E-class P450 group IV signature 260 286 2.7E-13 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS17055 8c44ee0d39ea7cb0e9d49b00df2be89c 456 PRINTS PR00465 E-class P450 group IV signature 388 404 2.7E-13 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS17055 8c44ee0d39ea7cb0e9d49b00df2be89c 456 Gene3D G3DSA:1.10.630.10 31 455 2.4E-97 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS17055 8c44ee0d39ea7cb0e9d49b00df2be89c 456 SUPERFAMILY SSF48264 31 455 3.67E-90 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS17055 8c44ee0d39ea7cb0e9d49b00df2be89c 456 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 397 406 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 BWK49_RS17055 8c44ee0d39ea7cb0e9d49b00df2be89c 456 PRINTS PR00385 P450 superfamily signature 320 331 1.6E-12 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS17055 8c44ee0d39ea7cb0e9d49b00df2be89c 456 PRINTS PR00385 P450 superfamily signature 395 404 1.6E-12 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS17055 8c44ee0d39ea7cb0e9d49b00df2be89c 456 PRINTS PR00385 P450 superfamily signature 269 286 1.6E-12 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS17055 8c44ee0d39ea7cb0e9d49b00df2be89c 456 PRINTS PR00385 P450 superfamily signature 404 415 1.6E-12 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS27315 b2f98f8b7a4f15d11506501b16437e51 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 1.8E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27315 b2f98f8b7a4f15d11506501b16437e51 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 1.8E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27315 b2f98f8b7a4f15d11506501b16437e51 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 1.8E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27315 b2f98f8b7a4f15d11506501b16437e51 242 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS27315 b2f98f8b7a4f15d11506501b16437e51 242 SUPERFAMILY SSF51735 4 239 3.93E-76 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS27315 b2f98f8b7a4f15d11506501b16437e51 242 Gene3D G3DSA:3.40.50.720 2 239 6.0E-79 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS27315 b2f98f8b7a4f15d11506501b16437e51 242 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 10 236 9.4E-61 T 06-07-2017 BWK49_RS27315 b2f98f8b7a4f15d11506501b16437e51 242 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4 182 0.0017 T 06-07-2017 BWK49_RS27315 b2f98f8b7a4f15d11506501b16437e51 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 5.7E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27315 b2f98f8b7a4f15d11506501b16437e51 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 5.7E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27315 b2f98f8b7a4f15d11506501b16437e51 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 5.7E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27315 b2f98f8b7a4f15d11506501b16437e51 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 5.7E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27315 b2f98f8b7a4f15d11506501b16437e51 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 5.7E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27315 b2f98f8b7a4f15d11506501b16437e51 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 201 221 5.7E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS25545 eb4c14fd13a67ab41b7838a94199acba 150 Pfam PF16877 Domain of unknown function (DUF5078) 33 149 6.9E-55 T 06-07-2017 IPR031702 Protein of unknown function DUF5078 BWK49_RS11120 6209e922eb17158467759910f02e2021 264 SUPERFAMILY SSF48498 117 207 4.82E-6 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS11120 6209e922eb17158467759910f02e2021 264 Gene3D G3DSA:1.10.357.10 41 214 2.3E-25 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS11120 6209e922eb17158467759910f02e2021 264 Pfam PF00440 Bacterial regulatory proteins, tetR family 52 97 1.6E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS11120 6209e922eb17158467759910f02e2021 264 SUPERFAMILY SSF46689 41 123 9.75E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS25185 d60c2300dff0f89cba2c3aeb9545ac19 305 Gene3D G3DSA:3.40.50.720 1 185 1.4E-45 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS25185 d60c2300dff0f89cba2c3aeb9545ac19 305 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 150 1.1E-36 T 06-07-2017 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 BWK49_RS25185 d60c2300dff0f89cba2c3aeb9545ac19 305 SUPERFAMILY SSF51735 1 168 2.23E-19 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS25185 d60c2300dff0f89cba2c3aeb9545ac19 305 Gene3D G3DSA:1.10.1040.10 186 303 1.9E-33 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 BWK49_RS25185 d60c2300dff0f89cba2c3aeb9545ac19 305 SUPERFAMILY SSF48179 177 302 2.38E-30 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 BWK49_RS25185 d60c2300dff0f89cba2c3aeb9545ac19 305 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 177 301 2.7E-31 T 06-07-2017 IPR013752 Ketopantoate reductase, C-terminal domain GO:0016491|GO:0050661|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 BWK49_RS25185 d60c2300dff0f89cba2c3aeb9545ac19 305 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 2 303 3.6E-70 T 06-07-2017 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0015940|GO:0016491|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 BWK49_RS16610 7e057f1701a6e89b3698cf1bb841d2bb 241 Pfam PF04079 Segregation and condensation complex subunit ScpB 41 197 2.2E-49 T 06-07-2017 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 BWK49_RS16610 7e057f1701a6e89b3698cf1bb841d2bb 241 PIRSF PIRSF019345 22 235 2.1E-61 T 06-07-2017 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 BWK49_RS16610 7e057f1701a6e89b3698cf1bb841d2bb 241 SUPERFAMILY SSF46785 117 189 2.27E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS16610 7e057f1701a6e89b3698cf1bb841d2bb 241 Gene3D G3DSA:1.10.10.10 33 112 4.4E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS16610 7e057f1701a6e89b3698cf1bb841d2bb 241 SUPERFAMILY SSF46785 33 112 1.7E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS16610 7e057f1701a6e89b3698cf1bb841d2bb 241 Gene3D G3DSA:1.10.10.10 117 189 5.6E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS16610 7e057f1701a6e89b3698cf1bb841d2bb 241 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 38 199 1.4E-31 T 06-07-2017 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 BWK49_RS08730 9be8a255b35b679fe49ac790b7f7dfde 588 SUPERFAMILY SSF56112 13 356 7.15E-73 T 06-07-2017 IPR011009 Protein kinase-like domain BWK49_RS08730 9be8a255b35b679fe49ac790b7f7dfde 588 Gene3D G3DSA:1.10.510.10 114 322 2.5E-45 T 06-07-2017 BWK49_RS08730 9be8a255b35b679fe49ac790b7f7dfde 588 Gene3D G3DSA:3.30.200.20 9 113 5.3E-22 T 06-07-2017 BWK49_RS08730 9be8a255b35b679fe49ac790b7f7dfde 588 Pfam PF00069 Protein kinase domain 16 279 2.0E-44 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 BWK49_RS08730 9be8a255b35b679fe49ac790b7f7dfde 588 Pfam PF14032 PknH-like extracellular domain 400 584 3.2E-53 T 06-07-2017 IPR026954 PknH-like extracellular domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 BWK49_RS08730 9be8a255b35b679fe49ac790b7f7dfde 588 SMART SM00220 16 276 4.4E-50 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 BWK49_RS08730 9be8a255b35b679fe49ac790b7f7dfde 588 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 135 147 - T 06-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 BWK49_RS08730 9be8a255b35b679fe49ac790b7f7dfde 588 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 22 45 - T 06-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 BWK49_RS10670 86215724d6c29831c3f264e5aba65fc2 510 Gene3D G3DSA:2.60.40.420 53 185 5.2E-30 T 06-07-2017 IPR008972 Cupredoxin BWK49_RS10670 86215724d6c29831c3f264e5aba65fc2 510 Pfam PF07731 Multicopper oxidase 395 503 3.5E-28 T 06-07-2017 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 BWK49_RS10670 86215724d6c29831c3f264e5aba65fc2 510 SUPERFAMILY SSF49503 60 184 5.08E-32 T 06-07-2017 IPR008972 Cupredoxin BWK49_RS10670 86215724d6c29831c3f264e5aba65fc2 510 Gene3D G3DSA:2.60.40.420 392 506 2.6E-41 T 06-07-2017 IPR008972 Cupredoxin BWK49_RS10670 86215724d6c29831c3f264e5aba65fc2 510 SUPERFAMILY SSF49503 184 366 4.66E-33 T 06-07-2017 IPR008972 Cupredoxin BWK49_RS10670 86215724d6c29831c3f264e5aba65fc2 510 Gene3D G3DSA:2.60.40.420 186 373 3.3E-46 T 06-07-2017 IPR008972 Cupredoxin BWK49_RS10670 86215724d6c29831c3f264e5aba65fc2 510 ProSitePatterns PS00079 Multicopper oxidases signature 1. 483 503 - T 06-07-2017 IPR033138 Multicopper oxidases, conserved site BWK49_RS10670 86215724d6c29831c3f264e5aba65fc2 510 SUPERFAMILY SSF49503 397 502 1.01E-33 T 06-07-2017 IPR008972 Cupredoxin BWK49_RS10670 86215724d6c29831c3f264e5aba65fc2 510 ProSitePatterns PS00080 Multicopper oxidases signature 2. 488 499 - T 06-07-2017 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 BWK49_RS10670 86215724d6c29831c3f264e5aba65fc2 510 Pfam PF07732 Multicopper oxidase 80 182 1.5E-25 T 06-07-2017 IPR011707 Multicopper oxidase, type 3 GO:0005507 BWK49_RS10670 86215724d6c29831c3f264e5aba65fc2 510 Pfam PF00394 Multicopper oxidase 191 336 2.5E-24 T 06-07-2017 IPR001117 Multicopper oxidase, type 1 GO:0016491|GO:0055114 BWK49_RS26455 69caae1b96a3b3e182dcc6c5da97b48c 539 TIGRFAM TIGR03919 T7SS_EccB: type VII secretion protein EccB 33 507 4.3E-167 T 06-07-2017 IPR007795 Type VII secretion system EccB BWK49_RS26455 69caae1b96a3b3e182dcc6c5da97b48c 539 Pfam PF05108 Type VII secretion system ESX-1, transport TM domain B 31 519 3.0E-180 T 06-07-2017 IPR007795 Type VII secretion system EccB BWK49_RS07750 857750a6639bea1dbb8b437a690bb665 290 Hamap MF_01482 Mycothiol S-conjugate amidase [mca]. 7 287 52.771 T 06-07-2017 IPR017811 Mycothiol S-conjugate amidase Mca GO:0010126 KEGG: 00311+3.5.1.11 BWK49_RS07750 857750a6639bea1dbb8b437a690bb665 290 SUPERFAMILY SSF102588 4 288 1.1E-72 T 06-07-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 BWK49_RS07750 857750a6639bea1dbb8b437a690bb665 290 Pfam PF02585 GlcNAc-PI de-N-acetylase 7 152 1.5E-26 T 06-07-2017 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 BWK49_RS07750 857750a6639bea1dbb8b437a690bb665 290 TIGRFAM TIGR03446 mycothiol_Mca: mycothiol conjugate amidase Mca 4 286 4.5E-155 T 06-07-2017 IPR017811 Mycothiol S-conjugate amidase Mca GO:0010126 KEGG: 00311+3.5.1.11 BWK49_RS07750 857750a6639bea1dbb8b437a690bb665 290 Gene3D G3DSA:3.40.50.10320 3 289 1.8E-88 T 06-07-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 BWK49_RS04845 695ffee6cb886bfad95b984927b4a933 163 Pfam PF00872 Transposase, Mutator family 5 105 1.3E-17 T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 BWK49_RS01900 806187910d8e07e280f889f8b28260b5 165 Pfam PF00866 Ring hydroxylating beta subunit 25 156 5.7E-15 T 06-07-2017 IPR000391 Ring-hydroxylating dioxygenase beta subunit GO:0003824|GO:0006725|GO:0055114 BWK49_RS01900 806187910d8e07e280f889f8b28260b5 165 SUPERFAMILY SSF54427 17 157 3.26E-31 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS01900 806187910d8e07e280f889f8b28260b5 165 Gene3D G3DSA:3.10.450.50 17 156 9.9E-26 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS16885 9890ce5364e9f3f0a6360fdd7f3cab98 480 SMART SM00382 225 393 8.6E-5 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS16885 9890ce5364e9f3f0a6360fdd7f3cab98 480 SUPERFAMILY SSF52540 192 443 2.4E-20 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS16885 9890ce5364e9f3f0a6360fdd7f3cab98 480 Pfam PF01580 FtsK/SpoIIIE family 203 397 4.6E-16 T 06-07-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 BWK49_RS16885 9890ce5364e9f3f0a6360fdd7f3cab98 480 Gene3D G3DSA:3.40.50.300 210 443 1.9E-17 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS02670 977cc262ad3dda9d50416549be4655ca 333 Pfam PF14518 Iron-containing redox enzyme 135 307 1.2E-42 T 06-07-2017 IPR028201 PqqC-like protein BWK49_RS02670 977cc262ad3dda9d50416549be4655ca 333 Gene3D G3DSA:1.20.910.10 121 326 2.7E-61 T 06-07-2017 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 BWK49_RS02670 977cc262ad3dda9d50416549be4655ca 333 SUPERFAMILY SSF48613 132 312 6.89E-9 T 06-07-2017 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 BWK49_RS02670 977cc262ad3dda9d50416549be4655ca 333 SMART SM01236 166 271 8.4E-36 T 06-07-2017 BWK49_RS06545 6eaa2b6e1ad0c46676582aace3999959 138 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 17 46 6.0E-6 T 06-07-2017 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal BWK49_RS06545 6eaa2b6e1ad0c46676582aace3999959 138 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 49 117 1.5E-13 T 06-07-2017 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal BWK49_RS06545 6eaa2b6e1ad0c46676582aace3999959 138 SUPERFAMILY SSF50249 17 122 6.0E-22 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS13870 9d4cb1b6b2bdc5bb77fa85be6ccd43d1 268 SUPERFAMILY SSF54637 4 114 1.84E-10 T 06-07-2017 IPR029069 HotDog domain BWK49_RS13870 9d4cb1b6b2bdc5bb77fa85be6ccd43d1 268 Pfam PF13622 Thioesterase-like superfamily 25 265 2.2E-45 T 06-07-2017 BWK49_RS13870 9d4cb1b6b2bdc5bb77fa85be6ccd43d1 268 SUPERFAMILY SSF54637 120 266 1.21E-25 T 06-07-2017 IPR029069 HotDog domain BWK49_RS13870 9d4cb1b6b2bdc5bb77fa85be6ccd43d1 268 Gene3D G3DSA:3.10.129.10 133 262 9.4E-8 T 06-07-2017 IPR029069 HotDog domain BWK49_RS13870 9d4cb1b6b2bdc5bb77fa85be6ccd43d1 268 Gene3D G3DSA:3.10.129.10 6 114 5.0E-5 T 06-07-2017 IPR029069 HotDog domain BWK49_RS25815 32a20f6cc19effb4b4b9fdef3579dbdc 307 Pfam PF04072 Leucine carboxyl methyltransferase 18 202 4.4E-65 T 06-07-2017 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 BWK49_RS25815 32a20f6cc19effb4b4b9fdef3579dbdc 307 SUPERFAMILY SSF53335 14 287 4.51E-79 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS25815 32a20f6cc19effb4b4b9fdef3579dbdc 307 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 16 284 1.6E-77 T 06-07-2017 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 BWK49_RS25815 32a20f6cc19effb4b4b9fdef3579dbdc 307 Gene3D G3DSA:3.40.50.150 80 217 2.6E-17 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS04935 b34ba8064cac69f6f5efe25c9090e6e7 504 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 18 312 4.8E-82 T 06-07-2017 IPR005693 Virulence factor Mce protein BWK49_RS04935 b34ba8064cac69f6f5efe25c9090e6e7 504 Pfam PF02470 MlaD protein 47 120 6.6E-13 T 06-07-2017 IPR003399 Mce/MlaD BWK49_RS21380 d0f16bd0b5174bb89a97af0b8dd12be3 164 SUPERFAMILY SSF110921 64 160 1.01E-15 T 06-07-2017 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 BWK49_RS21380 d0f16bd0b5174bb89a97af0b8dd12be3 164 SMART SM00917 33 161 0.0017 T 06-07-2017 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 BWK49_RS04705 fdbaf97326d67a778eafc16c1f35442a 170 Pfam PF13452 N-terminal half of MaoC dehydratase 23 158 2.3E-25 T 06-07-2017 BWK49_RS04705 fdbaf97326d67a778eafc16c1f35442a 170 SUPERFAMILY SSF54637 31 166 2.49E-8 T 06-07-2017 IPR029069 HotDog domain BWK49_RS04705 fdbaf97326d67a778eafc16c1f35442a 170 Gene3D G3DSA:3.10.129.10 8 164 1.1E-7 T 06-07-2017 IPR029069 HotDog domain BWK49_RS18940 52d67d5748e325fa1df7b97b8f4a8757 306 Pfam PF00248 Aldo/keto reductase family 38 299 3.0E-61 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain BWK49_RS18940 52d67d5748e325fa1df7b97b8f4a8757 306 SUPERFAMILY SSF51430 28 300 1.1E-79 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain BWK49_RS18940 52d67d5748e325fa1df7b97b8f4a8757 306 Gene3D G3DSA:3.20.20.100 32 303 7.2E-77 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain BWK49_RS18940 52d67d5748e325fa1df7b97b8f4a8757 306 PRINTS PR00069 Aldo-keto reductase signature 234 258 1.5E-5 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 BWK49_RS18940 52d67d5748e325fa1df7b97b8f4a8757 306 PRINTS PR00069 Aldo-keto reductase signature 132 150 1.5E-5 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 BWK49_RS18940 52d67d5748e325fa1df7b97b8f4a8757 306 PRINTS PR00069 Aldo-keto reductase signature 68 92 1.5E-5 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 BWK49_RS07775 c46bb70abe0d3f4eb19ccaa55d9b8264 262 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 31 262 33.606 T 06-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 BWK49_RS07775 c46bb70abe0d3f4eb19ccaa55d9b8264 262 Pfam PF01255 Putative undecaprenyl diphosphate synthase 39 261 3.0E-67 T 06-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 BWK49_RS07775 c46bb70abe0d3f4eb19ccaa55d9b8264 262 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 207 224 - T 06-07-2017 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 BWK49_RS07775 c46bb70abe0d3f4eb19ccaa55d9b8264 262 Gene3D G3DSA:3.40.1180.10 26 262 2.3E-82 T 06-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 BWK49_RS07775 c46bb70abe0d3f4eb19ccaa55d9b8264 262 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 31 261 1.1E-60 T 06-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 BWK49_RS07775 c46bb70abe0d3f4eb19ccaa55d9b8264 262 SUPERFAMILY SSF64005 28 256 2.49E-70 T 06-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 BWK49_RS01230 73f620a3778462c364c072e34773ac79 1071 Pfam PF04602 Mycobacterial cell wall arabinan synthesis protein 9 663 6.3E-275 T 06-07-2017 IPR007680 Arabinofuranosyltransferase, N-terminal GO:0052636|GO:0071766 BWK49_RS01230 73f620a3778462c364c072e34773ac79 1071 Pfam PF14896 EmbC C-terminal domain 699 1069 4.1E-151 T 06-07-2017 IPR032731 Arabinosyltransferase, C-terminal BWK49_RS01230 73f620a3778462c364c072e34773ac79 1071 Gene3D G3DSA:2.60.120.610 30 215 8.5E-65 T 06-07-2017 IPR027451 Arabinofuranosyltransferase, domain 1 BWK49_RS18980 fa500c77a42ce96559bd543b56625a95 118 SUPERFAMILY SSF54862 4 104 5.12E-21 T 06-07-2017 BWK49_RS18980 fa500c77a42ce96559bd543b56625a95 118 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site BWK49_RS18980 fa500c77a42ce96559bd543b56625a95 118 Gene3D G3DSA:3.30.70.20 7 68 1.2E-17 T 06-07-2017 BWK49_RS18980 fa500c77a42ce96559bd543b56625a95 118 Pfam PF00037 4Fe-4S binding domain 34 56 1.4E-8 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain BWK49_RS18980 fa500c77a42ce96559bd543b56625a95 118 PRINTS PR00354 7Fe ferredoxin signature 9 19 2.2E-16 T 06-07-2017 IPR000813 7Fe ferredoxin GO:0009055 BWK49_RS18980 fa500c77a42ce96559bd543b56625a95 118 PRINTS PR00354 7Fe ferredoxin signature 35 52 2.2E-16 T 06-07-2017 IPR000813 7Fe ferredoxin GO:0009055 BWK49_RS18980 fa500c77a42ce96559bd543b56625a95 118 PRINTS PR00354 7Fe ferredoxin signature 19 29 2.2E-16 T 06-07-2017 IPR000813 7Fe ferredoxin GO:0009055 BWK49_RS04995 e2562418424c3cca8f81d76cf5a67022 135 Gene3D G3DSA:3.30.1050.10 26 115 1.7E-10 T 06-07-2017 IPR003033 SCP2 sterol-binding domain BWK49_RS04995 e2562418424c3cca8f81d76cf5a67022 135 SUPERFAMILY SSF55718 15 115 1.15E-8 T 06-07-2017 IPR003033 SCP2 sterol-binding domain BWK49_RS00615 4608dccad7a65b14efb66d2c4e36866d 371 Pfam PF02470 MlaD protein 36 110 2.4E-11 T 06-07-2017 IPR003399 Mce/MlaD BWK49_RS00615 4608dccad7a65b14efb66d2c4e36866d 371 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 9 299 5.3E-48 T 06-07-2017 IPR005693 Virulence factor Mce protein BWK49_RS00615 4608dccad7a65b14efb66d2c4e36866d 371 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 42 - T 06-07-2017 IPR010916 TonB box, conserved site BWK49_RS08435 ceab2113d8f7cc7ed8c9705afb660808 272 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 188 270 6.4E-14 T 06-07-2017 IPR022171 PPE family, C-terminal BWK49_RS08435 ceab2113d8f7cc7ed8c9705afb660808 272 SUPERFAMILY SSF140459 8 84 3.14E-20 T 06-07-2017 BWK49_RS08435 ceab2113d8f7cc7ed8c9705afb660808 272 Pfam PF00934 PE family 1 92 2.7E-26 T 06-07-2017 IPR000084 PE-PGRS family, N-terminal BWK49_RS20110 ab5f3291973a3d503d96540ba0bc1845 314 Pfam PF01148 Cytidylyltransferase family 48 312 2.9E-59 T 06-07-2017 BWK49_RS20110 ab5f3291973a3d503d96540ba0bc1845 314 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 271 297 - T 06-07-2017 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981 BWK49_RS25515 2f52f6e30da7cc4f8d6c8b59d0c880ce 79 Pfam PF16936 Putative holin 1 78 6.8E-35 T 06-07-2017 IPR031614 Putative holin BWK49_RS27810 613e5a7b4ba6489a8192b16673036eed 249 Gene3D G3DSA:1.10.10.10 9 78 1.4E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS27810 613e5a7b4ba6489a8192b16673036eed 249 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 33 47 1.2E-8 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 BWK49_RS27810 613e5a7b4ba6489a8192b16673036eed 249 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 63 1.2E-8 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 BWK49_RS27810 613e5a7b4ba6489a8192b16673036eed 249 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 73 1.8E-20 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 BWK49_RS27810 613e5a7b4ba6489a8192b16673036eed 249 SUPERFAMILY SSF46785 3 77 3.81E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS27810 613e5a7b4ba6489a8192b16673036eed 249 Pfam PF07702 UTRA domain 108 236 1.1E-16 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 BWK49_RS27810 613e5a7b4ba6489a8192b16673036eed 249 SMART SM00866 96 236 9.4E-20 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 BWK49_RS27810 613e5a7b4ba6489a8192b16673036eed 249 SUPERFAMILY SSF64288 62 243 4.87E-28 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain BWK49_RS27810 613e5a7b4ba6489a8192b16673036eed 249 SMART SM00345 14 73 3.9E-20 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 BWK49_RS27810 613e5a7b4ba6489a8192b16673036eed 249 Gene3D G3DSA:3.40.1410.10 103 240 6.4E-29 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain BWK49_RS20380 a77afec771c19ab348aa33b826e9c321 1196 Gene3D G3DSA:3.40.50.300 2 163 2.5E-88 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS20380 a77afec771c19ab348aa33b826e9c321 1196 Gene3D G3DSA:3.40.50.300 1034 1179 2.5E-88 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS20380 a77afec771c19ab348aa33b826e9c321 1196 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 2 1185 0.0 T 06-07-2017 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 BWK49_RS20380 a77afec771c19ab348aa33b826e9c321 1196 SUPERFAMILY SSF52540 2 207 3.13E-70 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS20380 a77afec771c19ab348aa33b826e9c321 1196 SUPERFAMILY SSF52540 987 1178 3.13E-70 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS20380 a77afec771c19ab348aa33b826e9c321 1196 PIRSF PIRSF005719 1 1193 7.1E-271 T 06-07-2017 IPR024704 Structural maintenance of chromosomes protein BWK49_RS20380 a77afec771c19ab348aa33b826e9c321 1196 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 1177 9.7E-73 T 06-07-2017 IPR003395 RecF/RecN/SMC, N-terminal BWK49_RS20380 a77afec771c19ab348aa33b826e9c321 1196 SMART SM00968 510 622 5.7E-23 T 06-07-2017 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 BWK49_RS20380 a77afec771c19ab348aa33b826e9c321 1196 Hamap MF_01894 Chromosome partition protein Smc [smc]. 1 1187 22.491 T 06-07-2017 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 BWK49_RS20380 a77afec771c19ab348aa33b826e9c321 1196 SUPERFAMILY SSF75553 465 667 4.32E-31 T 06-07-2017 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 BWK49_RS20380 a77afec771c19ab348aa33b826e9c321 1196 Pfam PF06470 SMC proteins Flexible Hinge Domain 511 621 1.9E-21 T 06-07-2017 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 BWK49_RS27710 8d8db40e68a8622fd51b53a010c9115e 140 SUPERFAMILY SSF50475 12 139 4.3E-24 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 BWK49_RS27710 8d8db40e68a8622fd51b53a010c9115e 140 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 10 101 1.8E-15 T 06-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 BWK49_RS27710 8d8db40e68a8622fd51b53a010c9115e 140 TIGRFAM TIGR03668 Rv0121_F420: PPOX class probable F420-dependent enzyme, Rv0121 family 3 139 3.2E-65 T 06-07-2017 IPR019967 F420-dependent enzyme, PPOX class, family Rv0121, probable BWK49_RS27710 8d8db40e68a8622fd51b53a010c9115e 140 Gene3D G3DSA:2.30.110.10 7 139 9.8E-35 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 BWK49_RS07655 13fe04dfefb0864b680e36e6fdb2ac0c 296 Pfam PF13230 Glutamine amidotransferases class-II 1 260 4.0E-22 T 06-07-2017 IPR026869 Putative glutamine amidotransferase type 2 BWK49_RS07655 13fe04dfefb0864b680e36e6fdb2ac0c 296 Gene3D G3DSA:3.60.20.10 1 256 9.5E-51 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal BWK49_RS07655 13fe04dfefb0864b680e36e6fdb2ac0c 296 SUPERFAMILY SSF56235 2 256 1.2E-34 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal BWK49_RS06190 d253fa061b8489219f7ac43d2f1e6263 98 Pfam PF13459 4Fe-4S single cluster domain 3 61 3.4E-13 T 06-07-2017 BWK49_RS06190 d253fa061b8489219f7ac43d2f1e6263 98 SUPERFAMILY SSF54862 2 61 1.19E-8 T 06-07-2017 BWK49_RS06190 d253fa061b8489219f7ac43d2f1e6263 98 Gene3D G3DSA:3.30.70.20 1 61 1.6E-12 T 06-07-2017 BWK49_RS19760 4d4d61b3dfb80fd177b1879f3626fcde 335 Pfam PF00355 Rieske [2Fe-2S] domain 13 95 2.4E-15 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS19760 4d4d61b3dfb80fd177b1879f3626fcde 335 SUPERFAMILY SSF50022 10 119 6.94E-29 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS19760 4d4d61b3dfb80fd177b1879f3626fcde 335 SUPERFAMILY SSF55961 116 323 2.47E-14 T 06-07-2017 BWK49_RS19760 4d4d61b3dfb80fd177b1879f3626fcde 335 Gene3D G3DSA:2.102.10.10 12 123 8.8E-27 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS02015 209f76eda2a7bb0e7b4abaa60c1aff6c 458 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 40 328 1.8E-75 T 06-07-2017 IPR005693 Virulence factor Mce protein BWK49_RS02015 209f76eda2a7bb0e7b4abaa60c1aff6c 458 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 178 458 6.7E-105 T 06-07-2017 IPR024516 Mammalian cell entry, C-terminal BWK49_RS02015 209f76eda2a7bb0e7b4abaa60c1aff6c 458 Pfam PF02470 MlaD protein 70 148 4.5E-12 T 06-07-2017 IPR003399 Mce/MlaD BWK49_RS28170 81206a0c75d1c06089fe9b3d91f08b6b 363 SUPERFAMILY SSF54913 121 220 1.85E-24 T 06-07-2017 IPR011322 Nitrogen regulatory PII-like, alpha/beta BWK49_RS28170 81206a0c75d1c06089fe9b3d91f08b6b 363 Gene3D G3DSA:3.30.70.120 121 238 1.2E-37 T 06-07-2017 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal BWK49_RS28170 81206a0c75d1c06089fe9b3d91f08b6b 363 Gene3D G3DSA:3.30.70.120 7 112 4.9E-26 T 06-07-2017 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal BWK49_RS28170 81206a0c75d1c06089fe9b3d91f08b6b 363 Gene3D G3DSA:3.30.70.120 244 360 5.2E-35 T 06-07-2017 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal BWK49_RS28170 81206a0c75d1c06089fe9b3d91f08b6b 363 SUPERFAMILY SSF54913 244 342 3.78E-22 T 06-07-2017 IPR011322 Nitrogen regulatory PII-like, alpha/beta BWK49_RS28170 81206a0c75d1c06089fe9b3d91f08b6b 363 SUPERFAMILY SSF54913 8 106 1.89E-19 T 06-07-2017 IPR011322 Nitrogen regulatory PII-like, alpha/beta BWK49_RS28170 81206a0c75d1c06089fe9b3d91f08b6b 363 Pfam PF02641 Uncharacterized ACR, COG1993 246 341 7.3E-24 T 06-07-2017 IPR003793 Domain of unknown function DUF190 BWK49_RS28170 81206a0c75d1c06089fe9b3d91f08b6b 363 Pfam PF02641 Uncharacterized ACR, COG1993 125 219 6.2E-22 T 06-07-2017 IPR003793 Domain of unknown function DUF190 BWK49_RS28170 81206a0c75d1c06089fe9b3d91f08b6b 363 Pfam PF02641 Uncharacterized ACR, COG1993 11 104 4.7E-19 T 06-07-2017 IPR003793 Domain of unknown function DUF190 BWK49_RS23085 9c94f47d5f42c130ee9058f6f3840d0c 368 Gene3D G3DSA:3.40.190.10 47 195 3.2E-42 T 06-07-2017 BWK49_RS23085 9c94f47d5f42c130ee9058f6f3840d0c 368 Pfam PF12849 PBP superfamily domain 47 334 8.1E-49 T 06-07-2017 IPR024370 PBP domain BWK49_RS23085 9c94f47d5f42c130ee9058f6f3840d0c 368 SUPERFAMILY SSF53850 47 368 1.99E-77 T 06-07-2017 BWK49_RS23085 9c94f47d5f42c130ee9058f6f3840d0c 368 Gene3D G3DSA:3.40.190.10 227 366 7.0E-19 T 06-07-2017 BWK49_RS23085 9c94f47d5f42c130ee9058f6f3840d0c 368 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 47 367 7.5E-96 T 06-07-2017 IPR005673 ABC transporter, phosphate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 BWK49_RS23085 9c94f47d5f42c130ee9058f6f3840d0c 368 PIRSF PIRSF002756 3 368 4.8E-101 T 06-07-2017 IPR005673 ABC transporter, phosphate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 BWK49_RS22385 e48ea8d55192def01f10b7eec0f4c661 513 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 40 449 1.9E-118 T 06-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 BWK49_RS22385 e48ea8d55192def01f10b7eec0f4c661 513 Pfam PF07690 Major Facilitator Superfamily 42 438 1.9E-48 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 BWK49_RS22385 e48ea8d55192def01f10b7eec0f4c661 513 SUPERFAMILY SSF103473 24 219 5.62E-70 T 06-07-2017 IPR020846 Major facilitator superfamily domain BWK49_RS22385 e48ea8d55192def01f10b7eec0f4c661 513 SUPERFAMILY SSF103473 274 487 5.62E-70 T 06-07-2017 IPR020846 Major facilitator superfamily domain BWK49_RS22385 e48ea8d55192def01f10b7eec0f4c661 513 Gene3D G3DSA:1.20.1250.20 38 216 3.8E-27 T 06-07-2017 BWK49_RS22385 e48ea8d55192def01f10b7eec0f4c661 513 Gene3D G3DSA:1.20.1250.20 289 495 1.2E-22 T 06-07-2017 BWK49_RS15075 0a1f55f24ab4b675be94d3147e7fbb0c 209 SUPERFAMILY SSF46955 54 137 4.76E-14 T 06-07-2017 IPR009061 Putative DNA-binding domain BWK49_RS15075 0a1f55f24ab4b675be94d3147e7fbb0c 209 SMART SM00422 49 121 2.3E-19 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 BWK49_RS15075 0a1f55f24ab4b675be94d3147e7fbb0c 209 Pfam PF13411 MerR HTH family regulatory protein 53 118 7.1E-13 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 BWK49_RS15075 0a1f55f24ab4b675be94d3147e7fbb0c 209 Gene3D G3DSA:1.10.1660.10 54 125 2.9E-12 T 06-07-2017 BWK49_RS01125 77d0aa8c4de16f1062b0c20f6bca5d7d 341 Pfam PF01744 GLTT repeat (6 copies) 90 117 2.9E-6 T 06-07-2017 IPR008164 Repeat of unknown function XGLTT BWK49_RS01125 77d0aa8c4de16f1062b0c20f6bca5d7d 341 Pfam PF01744 GLTT repeat (6 copies) 115 140 2.0E-5 T 06-07-2017 IPR008164 Repeat of unknown function XGLTT BWK49_RS25175 2b57d4ba8553feead8821aa2e3fa718e 131 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 20 124 9.1E-26 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 BWK49_RS21445 bd9e5721910926cd57753a7be8f69e17 260 SUPERFAMILY SSF52096 7 255 1.42E-65 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS21445 bd9e5721910926cd57753a7be8f69e17 260 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 108 128 - T 06-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 BWK49_RS21445 bd9e5721910926cd57753a7be8f69e17 260 Gene3D G3DSA:3.90.226.10 9 256 6.0E-68 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS21445 bd9e5721910926cd57753a7be8f69e17 260 Pfam PF00378 Enoyl-CoA hydratase/isomerase 14 252 5.3E-49 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 BWK49_RS12485 33c51f23dc240fc0756e21bac5ddb8fe 140 Pfam PF11253 Protein of unknown function (DUF3052) 11 134 1.9E-56 T 06-07-2017 IPR021412 Protein of unknown function DUF3052 BWK49_RS26450 fd1e81643141e1ff9b5d417aba6b27a9 1329 Pfam PF01580 FtsK/SpoIIIE family 449 643 1.3E-19 T 06-07-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 BWK49_RS26450 fd1e81643141e1ff9b5d417aba6b27a9 1329 Pfam PF01580 FtsK/SpoIIIE family 1093 1142 1.1E-5 T 06-07-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 BWK49_RS26450 fd1e81643141e1ff9b5d417aba6b27a9 1329 Pfam PF01580 FtsK/SpoIIIE family 795 1043 1.9E-65 T 06-07-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 BWK49_RS26450 fd1e81643141e1ff9b5d417aba6b27a9 1329 SUPERFAMILY SSF52540 442 710 8.75E-26 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS26450 fd1e81643141e1ff9b5d417aba6b27a9 1329 TIGRFAM TIGR03925 T7SS_EccC_b: type VII secretion protein EccCb 761 1311 5.6E-165 T 06-07-2017 IPR023837 EccCb-like, Actinobacteria BWK49_RS26450 fd1e81643141e1ff9b5d417aba6b27a9 1329 Gene3D G3DSA:3.40.50.300 821 1006 7.9E-7 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS26450 fd1e81643141e1ff9b5d417aba6b27a9 1329 Gene3D G3DSA:3.40.50.300 1080 1141 2.8E-4 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS26450 fd1e81643141e1ff9b5d417aba6b27a9 1329 Gene3D G3DSA:3.40.50.300 451 686 2.3E-20 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS26450 fd1e81643141e1ff9b5d417aba6b27a9 1329 SUPERFAMILY SSF52540 1080 1304 6.14E-7 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS26450 fd1e81643141e1ff9b5d417aba6b27a9 1329 SMART SM00382 479 665 0.81 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS26450 fd1e81643141e1ff9b5d417aba6b27a9 1329 SMART SM00382 829 1005 0.39 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS26450 fd1e81643141e1ff9b5d417aba6b27a9 1329 SMART SM00382 1101 1274 0.032 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS26450 fd1e81643141e1ff9b5d417aba6b27a9 1329 SUPERFAMILY SSF52540 830 1007 2.05E-13 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS26450 fd1e81643141e1ff9b5d417aba6b27a9 1329 TIGRFAM TIGR03924 T7SS_EccC_a: type VII secretion protein EccCa 24 713 3.2E-229 T 06-07-2017 IPR023836 EccCa-like, Actinobacteria BWK49_RS00455 f195a92286c3bc7a0b63270695376b48 285 Gene3D G3DSA:3.20.20.30 2 234 1.7E-46 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS00455 f195a92286c3bc7a0b63270695376b48 285 TIGRFAM TIGR03619 F420_Rv2161c: probable F420-dependent oxidoreductase, Rv2161c family 18 256 4.6E-60 T 06-07-2017 IPR019921 Luciferase-like, F420-dependent oxidoreductase, Rv2161c, predicted BWK49_RS00455 f195a92286c3bc7a0b63270695376b48 285 SUPERFAMILY SSF51679 4 278 3.79E-44 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS00455 f195a92286c3bc7a0b63270695376b48 285 Pfam PF00296 Luciferase-like monooxygenase 23 234 1.0E-39 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS22825 0ba7bc8193e7d45f5af1c2eda579beb6 254 SUPERFAMILY SSF143081 2 243 5.36E-67 T 06-07-2017 IPR003738 SOS response associated peptidase (SRAP) BWK49_RS22825 0ba7bc8193e7d45f5af1c2eda579beb6 254 Pfam PF02586 SOS response associated peptidase (SRAP) 1 233 1.4E-67 T 06-07-2017 IPR003738 SOS response associated peptidase (SRAP) BWK49_RS22825 0ba7bc8193e7d45f5af1c2eda579beb6 254 Gene3D G3DSA:3.90.1680.10 1 243 1.8E-74 T 06-07-2017 IPR003738 SOS response associated peptidase (SRAP) BWK49_RS17410 26ec5dc4b29e03cab6d838cfd4abfbd8 468 Pfam PF00924 Mechanosensitive ion channel 114 307 1.4E-31 T 06-07-2017 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 BWK49_RS17410 26ec5dc4b29e03cab6d838cfd4abfbd8 468 SMART SM00100 331 448 1.4E-10 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain BWK49_RS17410 26ec5dc4b29e03cab6d838cfd4abfbd8 468 Pfam PF00027 Cyclic nucleotide-binding domain 350 434 4.3E-11 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain BWK49_RS17410 26ec5dc4b29e03cab6d838cfd4abfbd8 468 SUPERFAMILY SSF50182 157 221 8.17E-11 T 06-07-2017 IPR010920 LSM domain BWK49_RS17410 26ec5dc4b29e03cab6d838cfd4abfbd8 468 Gene3D G3DSA:2.30.30.60 172 219 5.7E-8 T 06-07-2017 BWK49_RS17410 26ec5dc4b29e03cab6d838cfd4abfbd8 468 PIRSF PIRSF026673 9 465 9.4E-114 T 06-07-2017 IPR016846 Predicted ion channel, cNMP-binding BWK49_RS17410 26ec5dc4b29e03cab6d838cfd4abfbd8 468 SUPERFAMILY SSF51206 335 456 2.75E-17 T 06-07-2017 IPR018490 Cyclic nucleotide-binding-like BWK49_RS17410 26ec5dc4b29e03cab6d838cfd4abfbd8 468 Gene3D G3DSA:2.60.120.10 334 450 6.8E-15 T 06-07-2017 IPR014710 RmlC-like jelly roll fold BWK49_RS10665 5c888bf33c5d6376610ac8e5ce876809 365 Pfam PF12849 PBP superfamily domain 41 331 2.7E-42 T 06-07-2017 IPR024370 PBP domain BWK49_RS10665 5c888bf33c5d6376610ac8e5ce876809 365 Gene3D G3DSA:3.40.190.10 43 192 3.6E-36 T 06-07-2017 BWK49_RS10665 5c888bf33c5d6376610ac8e5ce876809 365 PIRSF PIRSF002756 3 365 1.6E-95 T 06-07-2017 IPR005673 ABC transporter, phosphate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 BWK49_RS10665 5c888bf33c5d6376610ac8e5ce876809 365 Gene3D G3DSA:3.40.190.10 225 358 1.0E-12 T 06-07-2017 BWK49_RS10665 5c888bf33c5d6376610ac8e5ce876809 365 SUPERFAMILY SSF53850 44 365 8.03E-68 T 06-07-2017 BWK49_RS10665 5c888bf33c5d6376610ac8e5ce876809 365 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 44 364 8.6E-86 T 06-07-2017 IPR005673 ABC transporter, phosphate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 BWK49_RS13890 72c477e7efe5385614bdf0eb4d42a607 307 SUPERFAMILY SSF51679 1 301 1.57E-54 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS13890 72c477e7efe5385614bdf0eb4d42a607 307 Gene3D G3DSA:3.20.20.30 17 298 5.6E-52 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS13890 72c477e7efe5385614bdf0eb4d42a607 307 Pfam PF00296 Luciferase-like monooxygenase 15 282 4.0E-45 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS13890 72c477e7efe5385614bdf0eb4d42a607 307 TIGRFAM TIGR03564 F420_MSMEG_4879: F420-dependent oxidoreductase, MSMEG_4879 family 23 283 1.5E-80 T 06-07-2017 IPR019910 Luciferase-like, F420-dependent oxidoreductase, MSMEG4879, predicted BWK49_RS08035 8711dc7c5ecc5c35f314e78ef7eadc9b 574 Pfam PF12077 Transmembrane protein of unknown function (DUF3556) 1 571 6.6E-282 T 06-07-2017 IPR021941 Protein of unknown function DUF3556, transmembrane BWK49_RS20150 24952a3215f38ac884b171b4f830cab5 356 SUPERFAMILY SSF51004 50 170 3.14E-11 T 06-07-2017 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain BWK49_RS20150 24952a3215f38ac884b171b4f830cab5 356 SUPERFAMILY SSF51004 209 323 3.14E-11 T 06-07-2017 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain BWK49_RS20150 24952a3215f38ac884b171b4f830cab5 356 Gene3D G3DSA:2.130.10.10 92 181 2.8E-5 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 BWK49_RS20150 24952a3215f38ac884b171b4f830cab5 356 Gene3D G3DSA:2.130.10.10 221 317 2.8E-5 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 BWK49_RS18095 3d4b03618ed5b0f9f8b88eec4c0fd1f6 163 Pfam PF04224 Protein of unknown function, DUF417 65 147 3.5E-17 T 06-07-2017 IPR007339 Protein of unknown function DUF417 BWK49_RS18095 3d4b03618ed5b0f9f8b88eec4c0fd1f6 163 Pfam PF04224 Protein of unknown function, DUF417 17 61 4.5E-12 T 06-07-2017 IPR007339 Protein of unknown function DUF417 BWK49_RS18095 3d4b03618ed5b0f9f8b88eec4c0fd1f6 163 PIRSF PIRSF028065 7 153 3.6E-32 T 06-07-2017 IPR016865 Uncharacterised conserved protein UCP028065, membrane BWK49_RS18100 d4b41d8ee7620ef314c3307ddb95b04e 256 Gene3D G3DSA:3.40.50.720 2 253 2.5E-68 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS18100 d4b41d8ee7620ef314c3307ddb95b04e 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 2.2E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS18100 d4b41d8ee7620ef314c3307ddb95b04e 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 2.2E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS18100 d4b41d8ee7620ef314c3307ddb95b04e 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 2.2E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS18100 d4b41d8ee7620ef314c3307ddb95b04e 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 251 1.6E-48 T 06-07-2017 BWK49_RS18100 d4b41d8ee7620ef314c3307ddb95b04e 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 4.7E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS18100 d4b41d8ee7620ef314c3307ddb95b04e 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 4.7E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS18100 d4b41d8ee7620ef314c3307ddb95b04e 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 4.7E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS18100 d4b41d8ee7620ef314c3307ddb95b04e 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 4.7E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS18100 d4b41d8ee7620ef314c3307ddb95b04e 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 4.7E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS18100 d4b41d8ee7620ef314c3307ddb95b04e 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 4.7E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS18100 d4b41d8ee7620ef314c3307ddb95b04e 256 SUPERFAMILY SSF51735 4 253 6.86E-67 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS10530 a000ee0517f7b7092765612752de08bc 123 Pfam PF03965 Penicillinase repressor 7 118 2.6E-24 T 06-07-2017 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 BWK49_RS10530 a000ee0517f7b7092765612752de08bc 123 SUPERFAMILY SSF46785 4 120 1.66E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS10530 a000ee0517f7b7092765612752de08bc 123 Gene3D G3DSA:1.10.10.10 5 83 5.3E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS27695 cfc83caeea038edd36eec322f11e0289 446 SUPERFAMILY SSF56112 139 427 2.04E-16 T 06-07-2017 IPR011009 Protein kinase-like domain BWK49_RS05570 3db724ce57e93990c7ed3b8e930517b9 185 SUPERFAMILY SSF53098 30 181 1.21E-20 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS05570 3db724ce57e93990c7ed3b8e930517b9 185 Pfam PF00665 Integrase core domain 27 136 5.7E-11 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 BWK49_RS05570 3db724ce57e93990c7ed3b8e930517b9 185 Gene3D G3DSA:3.30.420.10 30 163 6.4E-8 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS05570 3db724ce57e93990c7ed3b8e930517b9 185 ProSitePatterns PS01043 Transposases, IS30 family, signature. 123 139 - T 06-07-2017 IPR001598 Transposase, IS30, conserved site GO:0003677|GO:0004803|GO:0006313 BWK49_RS25925 d942f0166054452cf5e077dd1a61900c 336 Pfam PF00296 Luciferase-like monooxygenase 11 307 8.3E-66 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS25925 d942f0166054452cf5e077dd1a61900c 336 TIGRFAM TIGR03554 F420_G6P_DH: glucose-6-phosphate dehydrogenase (coenzyme-F420) 3 333 3.8E-219 T 06-07-2017 IPR019944 F420-dependent glucose-6-phosphate dehydrogenase BWK49_RS25925 d942f0166054452cf5e077dd1a61900c 336 SUPERFAMILY SSF51679 4 333 6.93E-71 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS25925 d942f0166054452cf5e077dd1a61900c 336 Hamap MF_02123 F420-dependent glucose-6-phosphate dehydrogenase [fgd]. 3 335 69.54 T 06-07-2017 IPR019944 F420-dependent glucose-6-phosphate dehydrogenase BWK49_RS25925 d942f0166054452cf5e077dd1a61900c 336 TIGRFAM TIGR03557 F420_G6P_family: F420-dependent oxidoreductase, G6PDH family 6 333 1.1E-77 T 06-07-2017 IPR019945 F420-dependent glucose-6-phosphate dehydrogenase-related BWK49_RS25925 d942f0166054452cf5e077dd1a61900c 336 Gene3D G3DSA:3.20.20.30 4 334 2.1E-83 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS14665 ce1f82fdf1347b19a6bde999312a9b52 101 SUPERFAMILY SSF89957 3 98 4.58E-29 T 06-07-2017 IPR029756 MTH1187/YkoF-like BWK49_RS14665 ce1f82fdf1347b19a6bde999312a9b52 101 TIGRFAM TIGR00106 TIGR00106: uncharacterized protein, MTH1187 family 4 97 8.1E-18 T 06-07-2017 IPR002767 Thiamine-binding protein BWK49_RS14665 ce1f82fdf1347b19a6bde999312a9b52 101 Pfam PF01910 Thiamine-binding protein 5 95 9.2E-31 T 06-07-2017 IPR002767 Thiamine-binding protein BWK49_RS14665 ce1f82fdf1347b19a6bde999312a9b52 101 Gene3D G3DSA:3.30.70.930 2 96 1.5E-33 T 06-07-2017 IPR029756 MTH1187/YkoF-like BWK49_RS01255 1f8dc26fb9f24130bb995f1869894d7c 159 Gene3D G3DSA:3.10.50.30 87 156 3.7E-12 T 06-07-2017 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 BWK49_RS01255 1f8dc26fb9f24130bb995f1869894d7c 159 PIRSF PIRSF006092 1 159 4.1E-15 T 06-07-2017 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 BWK49_RS01255 1f8dc26fb9f24130bb995f1869894d7c 159 SUPERFAMILY SSF54534 87 155 6.15E-10 T 06-07-2017 BWK49_RS01255 1f8dc26fb9f24130bb995f1869894d7c 159 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 87 156 4.6E-11 T 06-07-2017 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 BWK49_RS19305 f1ffaeddf886b8f92fcb4e98182995b7 273 Gene3D G3DSA:3.90.226.10 9 264 1.4E-58 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS19305 f1ffaeddf886b8f92fcb4e98182995b7 273 Pfam PF00378 Enoyl-CoA hydratase/isomerase 22 269 3.4E-41 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 BWK49_RS19305 f1ffaeddf886b8f92fcb4e98182995b7 273 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 112 132 - T 06-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 BWK49_RS19305 f1ffaeddf886b8f92fcb4e98182995b7 273 SUPERFAMILY SSF52096 22 267 1.9E-63 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS23525 12ea355169de51e723ad6bfb79bf87b5 244 SUPERFAMILY SSF53335 12 195 1.42E-35 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS23525 12ea355169de51e723ad6bfb79bf87b5 244 Pfam PF08241 Methyltransferase domain 43 131 3.3E-22 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 BWK49_RS23525 12ea355169de51e723ad6bfb79bf87b5 244 Gene3D G3DSA:3.40.50.150 23 223 2.0E-32 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS20025 664117aa04937d4c0329c0a3144f5165 259 SUPERFAMILY SSF51735 11 252 1.02E-77 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS20025 664117aa04937d4c0329c0a3144f5165 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 252 8.2E-67 T 06-07-2017 BWK49_RS20025 664117aa04937d4c0329c0a3144f5165 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 1.3E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS20025 664117aa04937d4c0329c0a3144f5165 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 1.3E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS20025 664117aa04937d4c0329c0a3144f5165 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 1.3E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS20025 664117aa04937d4c0329c0a3144f5165 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 9.4E-44 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS20025 664117aa04937d4c0329c0a3144f5165 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 9.4E-44 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS20025 664117aa04937d4c0329c0a3144f5165 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 9.4E-44 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS20025 664117aa04937d4c0329c0a3144f5165 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 9.4E-44 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS20025 664117aa04937d4c0329c0a3144f5165 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 9.4E-44 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS20025 664117aa04937d4c0329c0a3144f5165 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 9.4E-44 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS20025 664117aa04937d4c0329c0a3144f5165 259 Gene3D G3DSA:3.40.50.720 6 252 1.9E-82 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS20955 e39baa64e4f5e86933de7049f66a9b5e 286 Pfam PF07681 DoxX 120 200 2.9E-17 T 06-07-2017 IPR032808 DoxX family BWK49_RS18670 dfcf789fe4747ad724a2a7034c7ae936 313 Pfam PF01841 Transglutaminase-like superfamily 148 255 1.8E-17 T 06-07-2017 IPR002931 Transglutaminase-like BWK49_RS18670 dfcf789fe4747ad724a2a7034c7ae936 313 SMART SM00460 183 257 7.0E-22 T 06-07-2017 IPR002931 Transglutaminase-like BWK49_RS18670 dfcf789fe4747ad724a2a7034c7ae936 313 Pfam PF08379 Bacterial transglutaminase-like N-terminal region 13 91 4.1E-18 T 06-07-2017 IPR013589 Bacterial transglutaminase-like, N-terminal BWK49_RS18670 dfcf789fe4747ad724a2a7034c7ae936 313 SUPERFAMILY SSF54001 125 297 3.36E-36 T 06-07-2017 BWK49_RS18670 dfcf789fe4747ad724a2a7034c7ae936 313 Gene3D G3DSA:3.90.260.10 187 263 4.7E-10 T 06-07-2017 IPR002931 Transglutaminase-like BWK49_RS10580 52ce2ae05d214042c2cc2893d755b76e 187 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 18 158 7.6E-9 T 06-07-2017 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS17935 f9a152fc6b75650016dd9f76e8140281 117 TIGRFAM TIGR01068 thioredoxin: thioredoxin 7 102 3.1E-31 T 06-07-2017 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 BWK49_RS17935 f9a152fc6b75650016dd9f76e8140281 117 PIRSF PIRSF000077 1 104 3.6E-26 T 06-07-2017 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 BWK49_RS17935 f9a152fc6b75650016dd9f76e8140281 117 Gene3D G3DSA:3.40.30.10 5 102 4.9E-31 T 06-07-2017 IPR012336 Thioredoxin-like fold BWK49_RS17935 f9a152fc6b75650016dd9f76e8140281 117 PRINTS PR00421 Thioredoxin family signature 29 38 3.8E-8 T 06-07-2017 BWK49_RS17935 f9a152fc6b75650016dd9f76e8140281 117 PRINTS PR00421 Thioredoxin family signature 21 29 3.8E-8 T 06-07-2017 BWK49_RS17935 f9a152fc6b75650016dd9f76e8140281 117 PRINTS PR00421 Thioredoxin family signature 68 79 3.8E-8 T 06-07-2017 BWK49_RS17935 f9a152fc6b75650016dd9f76e8140281 117 SUPERFAMILY SSF52833 5 103 6.53E-31 T 06-07-2017 IPR012336 Thioredoxin-like fold BWK49_RS17935 f9a152fc6b75650016dd9f76e8140281 117 Pfam PF00085 Thioredoxin 4 101 5.0E-25 T 06-07-2017 IPR013766 Thioredoxin domain GO:0045454 BWK49_RS17935 f9a152fc6b75650016dd9f76e8140281 117 ProSitePatterns PS00194 Thioredoxin family active site. 22 40 - T 06-07-2017 IPR017937 Thioredoxin, conserved site GO:0045454 BWK49_RS12265 e1436c74fba2df6c12393da2cb38fbdd 163 Pfam PF08044 Domain of unknown function (DUF1707) 12 62 1.5E-14 T 06-07-2017 IPR012551 Protein of unknown function DUF1707 BWK49_RS12265 e1436c74fba2df6c12393da2cb38fbdd 163 Pfam PF13239 2TM domain 74 135 2.3E-9 T 06-07-2017 IPR025698 2TM domain BWK49_RS15925 638b4ff257c864b3f3d589e2967b700a 165 SUPERFAMILY SSF50475 5 146 3.62E-33 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 BWK49_RS15925 638b4ff257c864b3f3d589e2967b700a 165 Pfam PF01613 Flavin reductase like domain 18 132 2.9E-17 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 BWK49_RS15925 638b4ff257c864b3f3d589e2967b700a 165 Gene3D G3DSA:2.30.110.10 8 139 1.1E-34 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 BWK49_RS15925 638b4ff257c864b3f3d589e2967b700a 165 SMART SM00903 13 155 3.7E-19 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 BWK49_RS16175 29f87fde873fcd39aa0300b1d9cbbdca 512 Gene3D G3DSA:1.20.1250.20 210 406 1.3E-11 T 06-07-2017 BWK49_RS16175 29f87fde873fcd39aa0300b1d9cbbdca 512 Gene3D G3DSA:1.20.1250.20 17 196 1.1E-24 T 06-07-2017 BWK49_RS16175 29f87fde873fcd39aa0300b1d9cbbdca 512 Pfam PF07690 Major Facilitator Superfamily 19 301 1.8E-23 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 BWK49_RS16175 29f87fde873fcd39aa0300b1d9cbbdca 512 SUPERFAMILY SSF103473 17 409 3.79E-43 T 06-07-2017 IPR020846 Major facilitator superfamily domain BWK49_RS27820 3edaf85cfc352d48d3e407d82b00bdfc 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 3.1E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27820 3edaf85cfc352d48d3e407d82b00bdfc 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 127 135 3.1E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27820 3edaf85cfc352d48d3e407d82b00bdfc 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 147 166 3.1E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27820 3edaf85cfc352d48d3e407d82b00bdfc 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 166 3.4E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27820 3edaf85cfc352d48d3e407d82b00bdfc 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 3.4E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27820 3edaf85cfc352d48d3e407d82b00bdfc 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 137 3.4E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27820 3edaf85cfc352d48d3e407d82b00bdfc 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 203 223 3.4E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27820 3edaf85cfc352d48d3e407d82b00bdfc 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 185 3.4E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27820 3edaf85cfc352d48d3e407d82b00bdfc 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 3.4E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS27820 3edaf85cfc352d48d3e407d82b00bdfc 257 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 8 240 1.5E-59 T 06-07-2017 BWK49_RS27820 3edaf85cfc352d48d3e407d82b00bdfc 257 Gene3D G3DSA:3.40.50.720 2 241 3.5E-78 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS27820 3edaf85cfc352d48d3e407d82b00bdfc 257 SUPERFAMILY SSF51735 2 240 4.05E-77 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS27820 3edaf85cfc352d48d3e407d82b00bdfc 257 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 134 162 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS03415 84078a5ca380ecb39cdf13fbde735774 387 Gene3D G3DSA:2.40.110.10 121 216 5.9E-35 T 06-07-2017 BWK49_RS03415 84078a5ca380ecb39cdf13fbde735774 387 Gene3D G3DSA:1.10.540.10 4 119 2.0E-25 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS03415 84078a5ca380ecb39cdf13fbde735774 387 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 210 5.2E-20 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 BWK49_RS03415 84078a5ca380ecb39cdf13fbde735774 387 SUPERFAMILY SSF47203 228 380 3.32E-15 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS03415 84078a5ca380ecb39cdf13fbde735774 387 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 118 3.3E-22 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS03415 84078a5ca380ecb39cdf13fbde735774 387 SUPERFAMILY SSF56645 4 241 1.96E-68 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS03415 84078a5ca380ecb39cdf13fbde735774 387 Gene3D G3DSA:1.20.140.10 217 384 1.1E-30 T 06-07-2017 BWK49_RS03415 84078a5ca380ecb39cdf13fbde735774 387 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 228 378 3.9E-24 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS00015 1fc143f36866d7f47f7fd496c9b7a53e 385 ProSitePatterns PS00618 RecF protein signature 2. 321 339 - T 06-07-2017 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 BWK49_RS00015 1fc143f36866d7f47f7fd496c9b7a53e 385 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 353 3.6E-17 T 06-07-2017 IPR003395 RecF/RecN/SMC, N-terminal BWK49_RS00015 1fc143f36866d7f47f7fd496c9b7a53e 385 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 385 94.546 T 06-07-2017 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 BWK49_RS00015 1fc143f36866d7f47f7fd496c9b7a53e 385 ProSitePatterns PS00617 RecF protein signature 1. 117 137 - T 06-07-2017 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 BWK49_RS00015 1fc143f36866d7f47f7fd496c9b7a53e 385 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 1 378 2.3E-129 T 06-07-2017 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 BWK49_RS00015 1fc143f36866d7f47f7fd496c9b7a53e 385 Gene3D G3DSA:3.40.50.300 2 171 2.2E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS00015 1fc143f36866d7f47f7fd496c9b7a53e 385 Gene3D G3DSA:3.40.50.300 254 352 2.2E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS00015 1fc143f36866d7f47f7fd496c9b7a53e 385 SUPERFAMILY SSF52540 3 222 3.19E-39 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS00015 1fc143f36866d7f47f7fd496c9b7a53e 385 SUPERFAMILY SSF52540 254 342 3.19E-39 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS06005 5db2f7883f48b0a7564e2d3b5188869b 414 SUPERFAMILY SSF55920 171 412 1.31E-48 T 06-07-2017 IPR000994 Peptidase M24, structural domain BWK49_RS06005 5db2f7883f48b0a7564e2d3b5188869b 414 Gene3D G3DSA:3.90.230.10 171 410 2.6E-43 T 06-07-2017 IPR000994 Peptidase M24, structural domain BWK49_RS06005 5db2f7883f48b0a7564e2d3b5188869b 414 Gene3D G3DSA:3.40.350.10 32 166 8.1E-11 T 06-07-2017 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal BWK49_RS06005 5db2f7883f48b0a7564e2d3b5188869b 414 SUPERFAMILY SSF53092 32 165 1.92E-11 T 06-07-2017 IPR028980 Creatinase/Aminopeptidase P, N-terminal BWK49_RS06005 5db2f7883f48b0a7564e2d3b5188869b 414 Pfam PF00557 Metallopeptidase family M24 179 398 2.4E-32 T 06-07-2017 IPR000994 Peptidase M24, structural domain BWK49_RS06005 5db2f7883f48b0a7564e2d3b5188869b 414 Pfam PF01321 Creatinase/Prolidase N-terminal domain 32 164 3.1E-6 T 06-07-2017 IPR000587 Creatinase, N-terminal GO:0016787 BWK49_RS21945 76bef0ba82cb9ec1549a02cb587db5a2 398 Gene3D G3DSA:3.40.50.1820 44 378 7.8E-29 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS21945 76bef0ba82cb9ec1549a02cb587db5a2 398 SUPERFAMILY SSF53474 40 168 2.45E-26 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS21945 76bef0ba82cb9ec1549a02cb587db5a2 398 SUPERFAMILY SSF53474 202 224 2.45E-26 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS21945 76bef0ba82cb9ec1549a02cb587db5a2 398 SUPERFAMILY SSF53474 299 380 2.45E-26 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS21945 76bef0ba82cb9ec1549a02cb587db5a2 398 Pfam PF12697 Alpha/beta hydrolase family 56 371 2.6E-8 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS18975 c3d5480e8321d120d866e2d25b157d4a 247 SUPERFAMILY SSF46785 36 217 5.45E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS18975 c3d5480e8321d120d866e2d25b157d4a 247 Gene3D G3DSA:1.10.10.10 36 97 3.7E-10 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS18975 c3d5480e8321d120d866e2d25b157d4a 247 Pfam PF09339 IclR helix-turn-helix domain 38 81 9.8E-6 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 BWK49_RS26820 4a19296c21a6184053f765501e9efb9c 411 Gene3D G3DSA:1.10.10.60 351 384 5.6E-5 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS26820 4a19296c21a6184053f765501e9efb9c 411 Pfam PF13556 PucR C-terminal helix-turn-helix domain 348 405 2.2E-20 T 06-07-2017 IPR025736 PucR C-terminal helix-turn-helix domain BWK49_RS15155 981657f3ea1d2b41bbf68ddcfddf5e98 225 SUPERFAMILY SSF50494 36 203 3.13E-19 T 06-07-2017 IPR009003 Peptidase S1, PA clan BWK49_RS15155 981657f3ea1d2b41bbf68ddcfddf5e98 225 Gene3D G3DSA:2.40.10.10 134 201 1.0E-7 T 06-07-2017 BWK49_RS15155 981657f3ea1d2b41bbf68ddcfddf5e98 225 Gene3D G3DSA:2.40.10.10 35 117 4.9E-6 T 06-07-2017 BWK49_RS01570 8bb3d0c0857437732b02445a8615eebb 178 SUPERFAMILY SSF54427 12 178 3.63E-44 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS01570 8bb3d0c0857437732b02445a8615eebb 178 Pfam PF00866 Ring hydroxylating beta subunit 23 170 4.0E-39 T 06-07-2017 IPR000391 Ring-hydroxylating dioxygenase beta subunit GO:0003824|GO:0006725|GO:0055114 BWK49_RS01570 8bb3d0c0857437732b02445a8615eebb 178 Gene3D G3DSA:3.10.450.50 10 178 1.1E-61 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS05890 4477b593a372cc2423cded63ad8c3696 538 SUPERFAMILY SSF56425 315 473 2.88E-29 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 BWK49_RS05890 4477b593a372cc2423cded63ad8c3696 538 Pfam PF00890 FAD binding domain 8 515 3.9E-78 T 06-07-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 BWK49_RS05890 4477b593a372cc2423cded63ad8c3696 538 Gene3D G3DSA:3.90.700.10 316 464 5.9E-28 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 BWK49_RS05890 4477b593a372cc2423cded63ad8c3696 538 SUPERFAMILY SSF51905 468 531 1.98E-40 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS05890 4477b593a372cc2423cded63ad8c3696 538 SUPERFAMILY SSF51905 1 124 1.98E-40 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS05890 4477b593a372cc2423cded63ad8c3696 538 SUPERFAMILY SSF51905 177 285 1.98E-40 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS05890 4477b593a372cc2423cded63ad8c3696 538 Gene3D G3DSA:3.50.50.60 161 288 7.3E-64 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS05890 4477b593a372cc2423cded63ad8c3696 538 Gene3D G3DSA:3.50.50.60 470 531 7.3E-64 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS05890 4477b593a372cc2423cded63ad8c3696 538 Gene3D G3DSA:3.50.50.60 2 104 7.3E-64 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS03095 5c9ec34430d3fbd2222e0e8f5b2d3306 139 TIGRFAM TIGR00223 panD: aspartate 1-decarboxylase 1 114 5.3E-51 T 06-07-2017 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 BWK49_RS03095 5c9ec34430d3fbd2222e0e8f5b2d3306 139 PIRSF PIRSF006246 1 134 5.7E-54 T 06-07-2017 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 BWK49_RS03095 5c9ec34430d3fbd2222e0e8f5b2d3306 139 SUPERFAMILY SSF50692 1 116 6.21E-49 T 06-07-2017 IPR009010 Aspartate decarboxylase-like domain BWK49_RS03095 5c9ec34430d3fbd2222e0e8f5b2d3306 139 Pfam PF02261 Aspartate decarboxylase 1 113 1.9E-51 T 06-07-2017 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 BWK49_RS03095 5c9ec34430d3fbd2222e0e8f5b2d3306 139 Gene3D G3DSA:2.40.40.20 1 118 1.7E-55 T 06-07-2017 BWK49_RS03095 5c9ec34430d3fbd2222e0e8f5b2d3306 139 Hamap MF_00446 Aspartate 1-decarboxylase [panD]. 1 130 75.446 T 06-07-2017 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 BWK49_RS03095 5c9ec34430d3fbd2222e0e8f5b2d3306 139 ProDom PD009294 ASPARTATE 1-DECARBOXYLASE DECARBOXYLASE CHAIN LYASE ALPHA ALPHA- CONTAINS: PRECURSOR BETA 5 95 9.0E-38 T 06-07-2017 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 BWK49_RS21245 8b26131df7e89edaa1a0843055f3837b 227 Pfam PF11738 Protein of unknown function (DUF3298) 145 219 1.7E-9 T 06-07-2017 IPR021729 Domain of unknown function DUF3298 BWK49_RS21245 8b26131df7e89edaa1a0843055f3837b 227 Gene3D G3DSA:3.90.640.20 185 224 1.4E-4 T 06-07-2017 IPR021729 Domain of unknown function DUF3298 BWK49_RS05790 a6f190382d46a573c9dc131d97ef2f66 318 SUPERFAMILY SSF51679 10 292 3.24E-53 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS05790 a6f190382d46a573c9dc131d97ef2f66 318 TIGRFAM TIGR03564 F420_MSMEG_4879: F420-dependent oxidoreductase, MSMEG_4879 family 22 286 1.6E-106 T 06-07-2017 IPR019910 Luciferase-like, F420-dependent oxidoreductase, MSMEG4879, predicted BWK49_RS05790 a6f190382d46a573c9dc131d97ef2f66 318 Pfam PF00296 Luciferase-like monooxygenase 4 283 2.6E-54 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS05790 a6f190382d46a573c9dc131d97ef2f66 318 Gene3D G3DSA:3.20.20.30 2 296 1.5E-51 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS16550 56cd2ffd1a35068d190296f78243f655 435 SMART SM00382 232 358 2.7E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS16550 56cd2ffd1a35068d190296f78243f655 435 Gene3D G3DSA:3.40.50.300 192 386 1.3E-29 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS16550 56cd2ffd1a35068d190296f78243f655 435 SUPERFAMILY SSF52540 193 406 4.5E-31 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS16550 56cd2ffd1a35068d190296f78243f655 435 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 236 355 1.7E-18 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 BWK49_RS22955 c70e0a7fe1bea89c292d232d36b43fdb 59 SUPERFAMILY SSF57802 1 48 1.99E-18 T 06-07-2017 BWK49_RS22955 c70e0a7fe1bea89c292d232d36b43fdb 59 ProSitePatterns PS00202 Rubredoxin signature. 33 43 - T 06-07-2017 IPR018527 Rubredoxin, iron-binding site GO:0046872 BWK49_RS22955 c70e0a7fe1bea89c292d232d36b43fdb 59 Pfam PF00301 Rubredoxin 4 50 4.0E-21 T 06-07-2017 IPR024935 Rubredoxin domain GO:0005506 BWK49_RS22955 c70e0a7fe1bea89c292d232d36b43fdb 59 PRINTS PR00163 Rubredoxin signature 3 19 3.9E-6 T 06-07-2017 IPR024935 Rubredoxin domain GO:0005506 BWK49_RS22955 c70e0a7fe1bea89c292d232d36b43fdb 59 PRINTS PR00163 Rubredoxin signature 33 49 3.9E-6 T 06-07-2017 IPR024935 Rubredoxin domain GO:0005506 BWK49_RS22955 c70e0a7fe1bea89c292d232d36b43fdb 59 Gene3D G3DSA:2.20.28.10 1 52 1.5E-22 T 06-07-2017 IPR004039 Rubredoxin-type fold BWK49_RS16620 e16f789ad97404541c50b90b0fd23d38 287 Gene3D G3DSA:3.40.50.300 34 284 2.1E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS16620 e16f789ad97404541c50b90b0fd23d38 287 SUPERFAMILY SSF52540 33 285 6.78E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS16620 e16f789ad97404541c50b90b0fd23d38 287 Pfam PF13614 AAA domain 34 210 4.2E-61 T 06-07-2017 IPR025669 AAA domain BWK49_RS24565 743201fecdf753e936ee1f31fab64b0c 298 PIRSF PIRSF003085 2 298 1.1E-98 T 06-07-2017 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 BWK49_RS24565 743201fecdf753e936ee1f31fab64b0c 298 Pfam PF02353 Mycolic acid cyclopropane synthetase 10 287 2.0E-116 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS24565 743201fecdf753e936ee1f31fab64b0c 298 SUPERFAMILY SSF53335 19 294 2.32E-74 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS24565 743201fecdf753e936ee1f31fab64b0c 298 Gene3D G3DSA:3.40.50.150 15 290 2.6E-82 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS00125 abcbf450ece75e99510ddb111d68b895 501 SMART SM00331 11 235 1.9E-54 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 BWK49_RS00125 abcbf450ece75e99510ddb111d68b895 501 Gene3D G3DSA:3.60.40.10 3 235 2.0E-68 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 BWK49_RS00125 abcbf450ece75e99510ddb111d68b895 501 Pfam PF13672 Protein phosphatase 2C 18 198 1.2E-14 T 06-07-2017 BWK49_RS00125 abcbf450ece75e99510ddb111d68b895 501 SUPERFAMILY SSF81606 4 234 4.45E-64 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 BWK49_RS00125 abcbf450ece75e99510ddb111d68b895 501 SMART SM00332 2 233 1.4E-34 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 BWK49_RS06750 e57e5852d3b8a7cd7f115473b054bb37 525 Gene3D G3DSA:3.40.710.10 45 399 1.2E-69 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like BWK49_RS06750 e57e5852d3b8a7cd7f115473b054bb37 525 Pfam PF00144 Beta-lactamase 56 385 1.7E-61 T 06-07-2017 IPR001466 Beta-lactamase-related BWK49_RS06750 e57e5852d3b8a7cd7f115473b054bb37 525 SUPERFAMILY SSF56601 50 399 2.72E-70 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like BWK49_RS06750 e57e5852d3b8a7cd7f115473b054bb37 525 Pfam PF11954 Domain of unknown function (DUF3471) 431 505 8.3E-11 T 06-07-2017 IPR021860 Peptidase S12, Pab87-related, C-terminal BWK49_RS07345 5b3d8d45d63e3bb784e0fe54de744a2e 491 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 340 470 9.7E-11 T 06-07-2017 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain BWK49_RS07345 5b3d8d45d63e3bb784e0fe54de744a2e 491 Pfam PF01943 Polysaccharide biosynthesis protein 27 266 8.0E-19 T 06-07-2017 IPR002797 Polysaccharide biosynthesis protein GO:0016020 BWK49_RS11705 5214d1432010f0827a8af2a2515a2915 244 SMART SM00857 3 159 9.2E-36 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 BWK49_RS11705 5214d1432010f0827a8af2a2515a2915 244 Pfam PF00239 Resolvase, N terminal domain 4 158 1.0E-26 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 BWK49_RS11705 5214d1432010f0827a8af2a2515a2915 244 Gene3D G3DSA:3.40.50.1390 1 142 2.5E-16 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 BWK49_RS11705 5214d1432010f0827a8af2a2515a2915 244 SUPERFAMILY SSF53041 1 158 6.41E-23 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 BWK49_RS11705 5214d1432010f0827a8af2a2515a2915 244 ProSitePatterns PS00397 Site-specific recombinases active site. 6 14 - T 06-07-2017 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 BWK49_RS05490 0b76db81d91274c6a6a3d06b81b225ec 539 Gene3D G3DSA:3.30.300.30 423 526 1.2E-28 T 06-07-2017 BWK49_RS05490 0b76db81d91274c6a6a3d06b81b225ec 539 Gene3D G3DSA:3.40.50.980 3 116 5.9E-32 T 06-07-2017 BWK49_RS05490 0b76db81d91274c6a6a3d06b81b225ec 539 Gene3D G3DSA:3.40.50.980 162 185 5.9E-32 T 06-07-2017 BWK49_RS05490 0b76db81d91274c6a6a3d06b81b225ec 539 SUPERFAMILY SSF56801 3 533 2.88E-132 T 06-07-2017 BWK49_RS05490 0b76db81d91274c6a6a3d06b81b225ec 539 Gene3D G3DSA:2.30.38.10 346 419 2.8E-18 T 06-07-2017 BWK49_RS05490 0b76db81d91274c6a6a3d06b81b225ec 539 Gene3D G3DSA:3.40.50.980 186 333 4.7E-34 T 06-07-2017 BWK49_RS05490 0b76db81d91274c6a6a3d06b81b225ec 539 ProSitePatterns PS00455 Putative AMP-binding domain signature. 177 188 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS05490 0b76db81d91274c6a6a3d06b81b225ec 539 Pfam PF00501 AMP-binding enzyme 8 427 1.4E-79 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS05490 0b76db81d91274c6a6a3d06b81b225ec 539 Pfam PF13193 AMP-binding enzyme C-terminal domain 437 517 1.2E-17 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS04105 1afca7a21816240b48ae2c9bdd51cdd5 156 Pfam PF14340 Domain of unknown function (DUF4395) 13 148 1.7E-42 T 06-07-2017 IPR025508 Domain of unknown function DUF4395 BWK49_RS12550 40ad2f7b4167cfa3787ab465c4b12220 379 SUPERFAMILY SSF53098 3 128 3.54E-30 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS12550 40ad2f7b4167cfa3787ab465c4b12220 379 SMART SM00855 179 333 5.3E-18 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 BWK49_RS12550 40ad2f7b4167cfa3787ab465c4b12220 379 PIRSF PIRSF036922 1 378 2.2E-195 T 06-07-2017 IPR014636 RNase H, phosphoglycerate mutase domain-containing BWK49_RS12550 40ad2f7b4167cfa3787ab465c4b12220 379 SUPERFAMILY SSF53254 177 377 8.9E-56 T 06-07-2017 IPR029033 Histidine phosphatase superfamily BWK49_RS12550 40ad2f7b4167cfa3787ab465c4b12220 379 Pfam PF13456 Reverse transcriptase-like 8 129 5.5E-23 T 06-07-2017 BWK49_RS12550 40ad2f7b4167cfa3787ab465c4b12220 379 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 180 372 1.5E-61 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 BWK49_RS12550 40ad2f7b4167cfa3787ab465c4b12220 379 Gene3D G3DSA:3.30.420.10 3 134 6.0E-22 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS12550 40ad2f7b4167cfa3787ab465c4b12220 379 Gene3D G3DSA:3.40.50.1240 176 378 1.1E-58 T 06-07-2017 IPR029033 Histidine phosphatase superfamily BWK49_RS20315 aebd787b0d3846513c30bba02bbcd966 295 Gene3D G3DSA:3.40.710.10 43 286 3.4E-68 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like BWK49_RS20315 aebd787b0d3846513c30bba02bbcd966 295 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 72 83 1.1E-9 T 06-07-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 BWK49_RS20315 aebd787b0d3846513c30bba02bbcd966 295 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 146 159 1.1E-9 T 06-07-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 BWK49_RS20315 aebd787b0d3846513c30bba02bbcd966 295 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 120 137 1.1E-9 T 06-07-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 BWK49_RS20315 aebd787b0d3846513c30bba02bbcd966 295 SUPERFAMILY SSF56601 15 285 4.11E-57 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like BWK49_RS20315 aebd787b0d3846513c30bba02bbcd966 295 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 46 261 5.6E-36 T 06-07-2017 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 BWK49_RS27850 71c7f3a66f8f67a9cc0ba4dd6030fcb8 244 Pfam PF05988 Bacterial protein of unknown function (DUF899) 1 219 6.0E-79 T 06-07-2017 IPR010296 Protein of unknown function DUF899, thioredoxin-like BWK49_RS03850 28b7778dcb0096b07508bebcea1c2e27 527 SUPERFAMILY SSF56235 9 527 5.21E-176 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal BWK49_RS03850 28b7778dcb0096b07508bebcea1c2e27 527 Pfam PF01019 Gamma-glutamyltranspeptidase 37 522 3.6E-158 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 BWK49_RS03850 28b7778dcb0096b07508bebcea1c2e27 527 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 110 128 6.8E-38 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 BWK49_RS03850 28b7778dcb0096b07508bebcea1c2e27 527 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 128 147 6.8E-38 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 BWK49_RS03850 28b7778dcb0096b07508bebcea1c2e27 527 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 372 390 6.8E-38 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 BWK49_RS03850 28b7778dcb0096b07508bebcea1c2e27 527 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 44 69 6.8E-38 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 BWK49_RS03850 28b7778dcb0096b07508bebcea1c2e27 527 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 403 418 6.8E-38 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 BWK49_RS03850 28b7778dcb0096b07508bebcea1c2e27 527 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 255 274 6.8E-38 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 BWK49_RS03850 28b7778dcb0096b07508bebcea1c2e27 527 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 427 444 6.8E-38 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 BWK49_RS03850 28b7778dcb0096b07508bebcea1c2e27 527 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 348 366 6.8E-38 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 BWK49_RS27640 a891f038a5c5446690f3479848e2d3b1 133 Gene3D G3DSA:3.30.310.70 6 131 1.3E-46 T 06-07-2017 IPR005180 Domain of unknown function DUF302 BWK49_RS27640 a891f038a5c5446690f3479848e2d3b1 133 Pfam PF03625 Domain of unknown function DUF302 35 101 7.1E-22 T 06-07-2017 IPR005180 Domain of unknown function DUF302 BWK49_RS27640 a891f038a5c5446690f3479848e2d3b1 133 PIRSF PIRSF021774 1 133 2.2E-41 T 06-07-2017 IPR016796 Uncharacterised conserved protein UCP021774 BWK49_RS27640 a891f038a5c5446690f3479848e2d3b1 133 SUPERFAMILY SSF103247 7 130 2.62E-33 T 06-07-2017 IPR005180 Domain of unknown function DUF302 BWK49_RS28335 5a1aa23b2d07b9685f8602f445325886 336 SUPERFAMILY SSF51905 2 307 1.3E-51 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS28335 5a1aa23b2d07b9685f8602f445325886 336 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 3.3E-36 T 06-07-2017 BWK49_RS28335 5a1aa23b2d07b9685f8602f445325886 336 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 233 249 3.3E-36 T 06-07-2017 BWK49_RS28335 5a1aa23b2d07b9685f8602f445325886 336 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 260 282 3.3E-36 T 06-07-2017 BWK49_RS28335 5a1aa23b2d07b9685f8602f445325886 336 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 107 125 3.3E-36 T 06-07-2017 BWK49_RS28335 5a1aa23b2d07b9685f8602f445325886 336 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 149 167 3.3E-36 T 06-07-2017 BWK49_RS28335 5a1aa23b2d07b9685f8602f445325886 336 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 137 157 - T 06-07-2017 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 BWK49_RS28335 5a1aa23b2d07b9685f8602f445325886 336 Gene3D G3DSA:3.50.50.60 111 301 3.9E-37 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS28335 5a1aa23b2d07b9685f8602f445325886 336 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 296 7.5E-47 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS28335 5a1aa23b2d07b9685f8602f445325886 336 Gene3D G3DSA:3.50.50.60 6 110 1.1E-33 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS28335 5a1aa23b2d07b9685f8602f445325886 336 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 7 307 2.2E-122 T 06-07-2017 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00240+1.8.1.9|KEGG: 00450+1.8.1.9 BWK49_RS28335 5a1aa23b2d07b9685f8602f445325886 336 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 235 256 1.5E-78 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 BWK49_RS28335 5a1aa23b2d07b9685f8602f445325886 336 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 41 56 1.5E-78 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 BWK49_RS28335 5a1aa23b2d07b9685f8602f445325886 336 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 62 72 1.5E-78 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 BWK49_RS28335 5a1aa23b2d07b9685f8602f445325886 336 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 145 169 1.5E-78 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 BWK49_RS28335 5a1aa23b2d07b9685f8602f445325886 336 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 270 288 1.5E-78 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 BWK49_RS28335 5a1aa23b2d07b9685f8602f445325886 336 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 108 116 1.5E-78 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 BWK49_RS28335 5a1aa23b2d07b9685f8602f445325886 336 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 130 142 1.5E-78 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 BWK49_RS28335 5a1aa23b2d07b9685f8602f445325886 336 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 197 213 1.5E-78 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 BWK49_RS28335 5a1aa23b2d07b9685f8602f445325886 336 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 8 30 1.5E-78 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 BWK49_RS10425 7609204d91ded961efc3cca77d605670 433 SMART SM00825 Beta-ketoacyl synthase 9 431 2.2E-111 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain BWK49_RS10425 7609204d91ded961efc3cca77d605670 433 Gene3D G3DSA:3.40.47.10 9 268 5.8E-71 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS10425 7609204d91ded961efc3cca77d605670 433 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 7 256 1.3E-67 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal BWK49_RS10425 7609204d91ded961efc3cca77d605670 433 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 265 376 1.9E-29 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal BWK49_RS10425 7609204d91ded961efc3cca77d605670 433 SUPERFAMILY SSF53901 406 427 1.04E-79 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS10425 7609204d91ded961efc3cca77d605670 433 SUPERFAMILY SSF53901 5 374 1.04E-79 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS10425 7609204d91ded961efc3cca77d605670 433 Gene3D G3DSA:3.40.47.10 272 427 1.2E-46 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS10425 7609204d91ded961efc3cca77d605670 433 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 169 185 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site BWK49_RS03235 80e739f7e29ff499a40967e0ee72c475 359 Gene3D G3DSA:1.10.260.40 7 60 2.2E-17 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 BWK49_RS03235 80e739f7e29ff499a40967e0ee72c475 359 SUPERFAMILY SSF53822 70 334 1.73E-38 T 06-07-2017 IPR028082 Periplasmic binding protein-like I BWK49_RS03235 80e739f7e29ff499a40967e0ee72c475 359 Gene3D G3DSA:3.40.50.2300 61 183 9.7E-23 T 06-07-2017 BWK49_RS03235 80e739f7e29ff499a40967e0ee72c475 359 SMART SM00354 8 79 8.4E-12 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 BWK49_RS03235 80e739f7e29ff499a40967e0ee72c475 359 SUPERFAMILY SSF47413 7 66 2.16E-11 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 BWK49_RS03235 80e739f7e29ff499a40967e0ee72c475 359 Pfam PF00356 Bacterial regulatory proteins, lacI family 10 53 1.2E-7 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 BWK49_RS03235 80e739f7e29ff499a40967e0ee72c475 359 Pfam PF13377 Periplasmic binding protein-like domain 181 353 1.9E-18 T 06-07-2017 BWK49_RS03235 80e739f7e29ff499a40967e0ee72c475 359 Gene3D G3DSA:3.40.50.2300 184 333 1.2E-32 T 06-07-2017 BWK49_RS17890 821589a00cf278570374ef2b86f17635 377 Gene3D G3DSA:1.10.8.300 233 349 2.7E-37 T 06-07-2017 BWK49_RS17890 821589a00cf278570374ef2b86f17635 377 Gene3D G3DSA:3.40.50.300 55 219 5.1E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS17890 821589a00cf278570374ef2b86f17635 377 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 73 203 2.0E-60 T 06-07-2017 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 BWK49_RS17890 821589a00cf278570374ef2b86f17635 377 PIRSF PIRSF002849 19 354 2.0E-137 T 06-07-2017 IPR016366 ATPase chaperone, AAA-type, MoxR, predicted BWK49_RS17890 821589a00cf278570374ef2b86f17635 377 SUPERFAMILY SSF52540 41 324 2.01E-42 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS06500 26eca07c40d15ebcfc2fc7e5d7fb0907 714 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 322 500 2.8E-62 T 06-07-2017 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 BWK49_RS06500 26eca07c40d15ebcfc2fc7e5d7fb0907 714 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 503 602 9.7E-19 T 06-07-2017 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 BWK49_RS06500 26eca07c40d15ebcfc2fc7e5d7fb0907 714 Gene3D G3DSA:3.90.226.10 240 299 6.4E-57 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS06500 26eca07c40d15ebcfc2fc7e5d7fb0907 714 Gene3D G3DSA:3.90.226.10 3 205 6.4E-57 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS06500 26eca07c40d15ebcfc2fc7e5d7fb0907 714 SUPERFAMILY SSF48179 628 712 3.49E-12 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 BWK49_RS06500 26eca07c40d15ebcfc2fc7e5d7fb0907 714 SUPERFAMILY SSF48179 502 642 1.87E-18 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 BWK49_RS06500 26eca07c40d15ebcfc2fc7e5d7fb0907 714 Pfam PF00378 Enoyl-CoA hydratase/isomerase 13 205 9.5E-35 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 BWK49_RS06500 26eca07c40d15ebcfc2fc7e5d7fb0907 714 SUPERFAMILY SSF51735 319 501 9.4E-59 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS06500 26eca07c40d15ebcfc2fc7e5d7fb0907 714 Gene3D G3DSA:1.10.1040.10 505 602 1.0E-12 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 BWK49_RS06500 26eca07c40d15ebcfc2fc7e5d7fb0907 714 Gene3D G3DSA:3.40.50.720 317 504 1.8E-56 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS06500 26eca07c40d15ebcfc2fc7e5d7fb0907 714 SUPERFAMILY SSF52096 3 304 1.05E-61 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS05540 b88e4a1ffad16ba4118c84bf70373824 105 SUPERFAMILY SSF53098 1 99 1.27E-15 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS05540 b88e4a1ffad16ba4118c84bf70373824 105 Pfam PF00665 Integrase core domain 2 94 1.3E-10 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 BWK49_RS05540 b88e4a1ffad16ba4118c84bf70373824 105 Gene3D G3DSA:3.30.420.10 1 96 1.2E-14 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS09390 6bb27055fe1328d54542026e52070c86 209 Pfam PF00857 Isochorismatase family 14 199 4.1E-31 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 BWK49_RS09390 6bb27055fe1328d54542026e52070c86 209 Gene3D G3DSA:3.40.50.850 10 206 2.6E-41 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 BWK49_RS09390 6bb27055fe1328d54542026e52070c86 209 SUPERFAMILY SSF52499 8 204 1.44E-40 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 BWK49_RS26055 53679abe3d6f1236cd1139a9a943b574 379 Gene3D G3DSA:1.50.10.10 37 251 1.1E-17 T 06-07-2017 IPR012341 Six-hairpin glycosidase GO:0003824 BWK49_RS26055 53679abe3d6f1236cd1139a9a943b574 379 Pfam PF03663 Glycosyl hydrolase family 76 14 325 5.2E-30 T 06-07-2017 IPR005198 Glycoside hydrolase, family 76 KEGG: 00052+3.2.1.10|KEGG: 00500+3.2.1.10 BWK49_RS26055 53679abe3d6f1236cd1139a9a943b574 379 SUPERFAMILY SSF48208 24 295 1.11E-26 T 06-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 BWK49_RS26055 53679abe3d6f1236cd1139a9a943b574 379 PIRSF PIRSF021505 1 378 8.9E-90 T 06-07-2017 IPR014512 Predicted O-glycosyl hydrolase BWK49_RS21130 ac9cdc342709270779950006bb247f63 359 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 237 249 - T 06-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 BWK49_RS21130 ac9cdc342709270779950006bb247f63 359 SUPERFAMILY SSF48576 37 357 7.2E-66 T 06-07-2017 IPR008949 Isoprenoid synthase domain BWK49_RS21130 ac9cdc342709270779950006bb247f63 359 Gene3D G3DSA:1.10.600.10 23 357 1.6E-70 T 06-07-2017 IPR008949 Isoprenoid synthase domain BWK49_RS21130 ac9cdc342709270779950006bb247f63 359 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 93 107 - T 06-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 BWK49_RS21130 ac9cdc342709270779950006bb247f63 359 Pfam PF00348 Polyprenyl synthetase 47 300 9.6E-44 T 06-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 BWK49_RS07395 fea936f4acb047f2ac037663cd98fccc 119 Pfam PF04075 Domain of unknown function (DUF385) 35 85 6.3E-5 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 BWK49_RS12225 7974f3a147b6ea95a23d14d9e972bb38 330 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 296 1.7E-46 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS12225 7974f3a147b6ea95a23d14d9e972bb38 330 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 137 157 - T 06-07-2017 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 BWK49_RS12225 7974f3a147b6ea95a23d14d9e972bb38 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 62 72 1.7E-78 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 BWK49_RS12225 7974f3a147b6ea95a23d14d9e972bb38 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 130 142 1.7E-78 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 BWK49_RS12225 7974f3a147b6ea95a23d14d9e972bb38 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 197 213 1.7E-78 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 BWK49_RS12225 7974f3a147b6ea95a23d14d9e972bb38 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 145 169 1.7E-78 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 BWK49_RS12225 7974f3a147b6ea95a23d14d9e972bb38 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 41 56 1.7E-78 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 BWK49_RS12225 7974f3a147b6ea95a23d14d9e972bb38 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 235 256 1.7E-78 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 BWK49_RS12225 7974f3a147b6ea95a23d14d9e972bb38 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 270 288 1.7E-78 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 BWK49_RS12225 7974f3a147b6ea95a23d14d9e972bb38 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 8 30 1.7E-78 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 BWK49_RS12225 7974f3a147b6ea95a23d14d9e972bb38 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 108 116 1.7E-78 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 BWK49_RS12225 7974f3a147b6ea95a23d14d9e972bb38 330 SUPERFAMILY SSF51905 2 307 5.42E-52 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS12225 7974f3a147b6ea95a23d14d9e972bb38 330 Gene3D G3DSA:3.50.50.60 5 110 2.1E-34 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS12225 7974f3a147b6ea95a23d14d9e972bb38 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 107 125 3.1E-36 T 06-07-2017 BWK49_RS12225 7974f3a147b6ea95a23d14d9e972bb38 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 149 167 3.1E-36 T 06-07-2017 BWK49_RS12225 7974f3a147b6ea95a23d14d9e972bb38 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 233 249 3.1E-36 T 06-07-2017 BWK49_RS12225 7974f3a147b6ea95a23d14d9e972bb38 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 260 282 3.1E-36 T 06-07-2017 BWK49_RS12225 7974f3a147b6ea95a23d14d9e972bb38 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 3.1E-36 T 06-07-2017 BWK49_RS12225 7974f3a147b6ea95a23d14d9e972bb38 330 Gene3D G3DSA:3.50.50.60 111 301 5.9E-37 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS12225 7974f3a147b6ea95a23d14d9e972bb38 330 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 7 307 9.8E-123 T 06-07-2017 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00240+1.8.1.9|KEGG: 00450+1.8.1.9 BWK49_RS19585 344d7c66267c9af23e07c652ed856ebd 212 SUPERFAMILY SSF52218 11 205 2.33E-25 T 06-07-2017 IPR029039 Flavoprotein-like domain BWK49_RS19585 344d7c66267c9af23e07c652ed856ebd 212 Pfam PF03358 NADPH-dependent FMN reductase 14 165 1.2E-20 T 06-07-2017 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 BWK49_RS19585 344d7c66267c9af23e07c652ed856ebd 212 Gene3D G3DSA:3.40.50.360 11 205 2.9E-16 T 06-07-2017 IPR029039 Flavoprotein-like domain BWK49_RS22255 f8f96e719ac7e991271bdf85ddb3392a 323 SUPERFAMILY SSF51430 11 301 1.83E-71 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain BWK49_RS22255 f8f96e719ac7e991271bdf85ddb3392a 323 Pfam PF00248 Aldo/keto reductase family 14 299 5.2E-56 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain BWK49_RS22255 f8f96e719ac7e991271bdf85ddb3392a 323 PRINTS PR00069 Aldo-keto reductase signature 101 119 6.1E-5 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 BWK49_RS22255 f8f96e719ac7e991271bdf85ddb3392a 323 PRINTS PR00069 Aldo-keto reductase signature 132 149 6.1E-5 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 BWK49_RS22255 f8f96e719ac7e991271bdf85ddb3392a 323 Gene3D G3DSA:3.20.20.100 11 304 3.1E-72 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain BWK49_RS23825 e9eeffa1943a540d5c11d4d60e4751b1 190 Gene3D G3DSA:1.20.1290.10 36 178 1.7E-19 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 BWK49_RS23825 e9eeffa1943a540d5c11d4d60e4751b1 190 Pfam PF02627 Carboxymuconolactone decarboxylase family 46 108 8.2E-11 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 BWK49_RS23825 e9eeffa1943a540d5c11d4d60e4751b1 190 SUPERFAMILY SSF69118 34 177 9.81E-24 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 BWK49_RS21405 d7caa696f82d96a7fff5aeb189298464 111 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 3 30 1.4E-5 T 06-07-2017 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal BWK49_RS21405 d7caa696f82d96a7fff5aeb189298464 111 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 35 97 1.2E-20 T 06-07-2017 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal BWK49_RS21405 d7caa696f82d96a7fff5aeb189298464 111 SUPERFAMILY SSF50249 2 99 9.25E-22 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS08380 b52ba02c5460be98677e163d0c374e41 319 SUPERFAMILY SSF51730 42 314 5.49E-74 T 06-07-2017 IPR029041 FAD-linked oxidoreductase-like BWK49_RS08380 b52ba02c5460be98677e163d0c374e41 319 Pfam PF01619 Proline dehydrogenase 52 311 8.3E-31 T 06-07-2017 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922 BWK49_RS08380 b52ba02c5460be98677e163d0c374e41 319 PIRSF PIRSF000196 6 319 3.7E-104 T 06-07-2017 IPR008219 Proline dehydrogenase GO:0004657|GO:0010133 KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922 BWK49_RS08380 b52ba02c5460be98677e163d0c374e41 319 Gene3D G3DSA:3.20.20.220 42 314 2.6E-73 T 06-07-2017 IPR029041 FAD-linked oxidoreductase-like BWK49_RS06325 bb590ea8d6fd8879236279e91420f5d9 525 Gene3D G3DSA:3.40.605.10 43 301 6.2E-76 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 BWK49_RS06325 bb590ea8d6fd8879236279e91420f5d9 525 SUPERFAMILY SSF53720 42 516 4.97E-146 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 BWK49_RS06325 bb590ea8d6fd8879236279e91420f5d9 525 Pfam PF00171 Aldehyde dehydrogenase family 54 512 2.1E-148 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 BWK49_RS06325 bb590ea8d6fd8879236279e91420f5d9 525 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 290 297 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 BWK49_RS06325 bb590ea8d6fd8879236279e91420f5d9 525 Gene3D G3DSA:3.40.309.10 302 488 2.1E-64 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 BWK49_RS21235 2961ad6993254398ae4000861c30d9ce 444 SUPERFAMILY SSF50998 41 62 6.47E-12 T 06-07-2017 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily BWK49_RS21235 2961ad6993254398ae4000861c30d9ce 444 SUPERFAMILY SSF50998 103 209 6.47E-12 T 06-07-2017 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily BWK49_RS21235 2961ad6993254398ae4000861c30d9ce 444 SUPERFAMILY SSF50998 283 441 6.47E-12 T 06-07-2017 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily BWK49_RS21235 2961ad6993254398ae4000861c30d9ce 444 Gene3D G3DSA:2.140.10.10 20 442 1.2E-14 T 06-07-2017 IPR027295 Quinoprotein alcohol dehydrogenase-like domain BWK49_RS21235 2961ad6993254398ae4000861c30d9ce 444 Pfam PF13360 PQQ-like domain 272 415 8.8E-6 T 06-07-2017 IPR002372 Pyrrolo-quinoline quinone repeat BWK49_RS24525 e9a1d6658d9ec5f9c4f742d9cc6ed49c 306 Gene3D G3DSA:3.30.420.40 142 287 7.2E-48 T 06-07-2017 BWK49_RS24525 e9a1d6658d9ec5f9c4f742d9cc6ed49c 306 ProSitePatterns PS01125 ROK family signature. 138 165 - T 06-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 BWK49_RS24525 e9a1d6658d9ec5f9c4f742d9cc6ed49c 306 Pfam PF00480 ROK family 4 303 5.0E-59 T 06-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 BWK49_RS24525 e9a1d6658d9ec5f9c4f742d9cc6ed49c 306 Gene3D G3DSA:3.30.420.40 3 141 1.1E-37 T 06-07-2017 BWK49_RS24525 e9a1d6658d9ec5f9c4f742d9cc6ed49c 306 SUPERFAMILY SSF53067 1 304 5.44E-59 T 06-07-2017 BWK49_RS04955 dfcc1674aa848f95b6603f740f8f693a 307 SUPERFAMILY SSF47240 4 235 1.98E-40 T 06-07-2017 IPR009078 Ferritin-like superfamily BWK49_RS18900 b6e399f242e2ebaeb62c7c48fddd35ae 374 Gene3D G3DSA:3.40.50.2000 186 340 2.0E-26 T 06-07-2017 BWK49_RS18900 b6e399f242e2ebaeb62c7c48fddd35ae 374 Pfam PF13439 Glycosyltransferase Family 4 14 172 5.3E-25 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 BWK49_RS18900 b6e399f242e2ebaeb62c7c48fddd35ae 374 Pfam PF13692 Glycosyl transferases group 1 189 329 6.3E-35 T 06-07-2017 BWK49_RS18900 b6e399f242e2ebaeb62c7c48fddd35ae 374 SUPERFAMILY SSF53756 2 363 5.93E-77 T 06-07-2017 BWK49_RS20345 f3dfefb096328b4e49161b0e271228bb 587 Gene3D G3DSA:3.40.50.300 299 392 4.5E-7 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS20345 f3dfefb096328b4e49161b0e271228bb 587 Gene3D G3DSA:3.40.50.300 21 181 2.2E-17 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS20345 f3dfefb096328b4e49161b0e271228bb 587 SUPERFAMILY SSF52540 21 181 8.62E-26 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS20345 f3dfefb096328b4e49161b0e271228bb 587 SUPERFAMILY SSF52540 42 96 4.35E-18 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS20345 f3dfefb096328b4e49161b0e271228bb 587 SUPERFAMILY SSF52540 303 401 4.35E-18 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS20345 f3dfefb096328b4e49161b0e271228bb 587 SMART SM00487 21 199 1.3E-15 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain BWK49_RS20345 f3dfefb096328b4e49161b0e271228bb 587 Pfam PF04851 Type III restriction enzyme, res subunit 25 177 1.7E-13 T 06-07-2017 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 BWK49_RS14465 0a219f3c0bab290e31bcc1dbc380268c 272 SUPERFAMILY SSF53335 54 190 6.72E-21 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS14465 0a219f3c0bab290e31bcc1dbc380268c 272 Gene3D G3DSA:3.40.50.150 63 187 5.1E-17 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS14465 0a219f3c0bab290e31bcc1dbc380268c 272 Pfam PF13649 Methyltransferase domain 83 175 3.2E-12 T 06-07-2017 BWK49_RS05605 9afcbb1e45533c3cfcf4b28f148e155e 65 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 21 41 - T 06-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 BWK49_RS05605 9afcbb1e45533c3cfcf4b28f148e155e 65 Pfam PF00378 Enoyl-CoA hydratase/isomerase 16 62 6.0E-11 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 BWK49_RS05605 9afcbb1e45533c3cfcf4b28f148e155e 65 SUPERFAMILY SSF52096 11 61 6.04E-16 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS05605 9afcbb1e45533c3cfcf4b28f148e155e 65 Gene3D G3DSA:3.90.226.10 16 62 1.7E-15 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS04375 a5de7206007c7786025a2182b7e05bdd 496 TIGRFAM TIGR03919 T7SS_EccB: type VII secretion protein EccB 7 469 1.2E-143 T 06-07-2017 IPR007795 Type VII secretion system EccB BWK49_RS04375 a5de7206007c7786025a2182b7e05bdd 496 Pfam PF05108 Type VII secretion system ESX-1, transport TM domain B 4 477 2.0E-133 T 06-07-2017 IPR007795 Type VII secretion system EccB BWK49_RS12825 9f29e4a0d4e374f2c1091edc945d135e 253 Pfam PF02654 Cobalamin-5-phosphate synthase 8 244 1.5E-43 T 06-07-2017 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 BWK49_RS12825 9f29e4a0d4e374f2c1091edc945d135e 253 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 253 40.739 T 06-07-2017 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 BWK49_RS26300 fe3d3b20c07dcc739d342d39b6b7607b 223 Pfam PF11139 Sap, sulfolipid-1-addressing protein 12 221 1.0E-61 T 06-07-2017 IPR021315 Glycolipid exporter Gap/Sap BWK49_RS09065 e908871f58c48aa1997bfd4b256c7ac9 155 Gene3D G3DSA:3.10.180.10 19 152 3.9E-38 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS09065 e908871f58c48aa1997bfd4b256c7ac9 155 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 22 137 1.8E-22 T 06-07-2017 BWK49_RS09065 e908871f58c48aa1997bfd4b256c7ac9 155 TIGRFAM TIGR03081 metmalonyl_epim: methylmalonyl-CoA epimerase 21 152 1.0E-40 T 06-07-2017 IPR017515 Methylmalonyl-CoA epimerase KEGG: 00280+5.1.99.1|KEGG: 00630+5.1.99.1|KEGG: 00640+5.1.99.1|KEGG: 00720+5.1.99.1|MetaCyc: PWY-5741|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384|Reactome: R-HSA-71032 BWK49_RS09065 e908871f58c48aa1997bfd4b256c7ac9 155 SUPERFAMILY SSF54593 18 153 1.02E-34 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS19655 3eb3d73923083e3f5ee7613ba90a43c9 290 Gene3D G3DSA:3.40.50.150 81 205 1.9E-14 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS19655 3eb3d73923083e3f5ee7613ba90a43c9 290 SUPERFAMILY SSF53335 6 283 1.16E-53 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS19655 3eb3d73923083e3f5ee7613ba90a43c9 290 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 8 270 7.7E-71 T 06-07-2017 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 BWK49_RS19655 3eb3d73923083e3f5ee7613ba90a43c9 290 Pfam PF04072 Leucine carboxyl methyltransferase 11 193 3.5E-37 T 06-07-2017 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 BWK49_RS10365 8dd48046380341a18a21a727ef8f3384 270 Gene3D G3DSA:3.40.50.300 77 248 4.8E-22 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS10365 8dd48046380341a18a21a727ef8f3384 270 Pfam PF01695 IstB-like ATP binding protein 75 248 6.6E-53 T 06-07-2017 IPR002611 IstB-like ATP-binding protein GO:0005524 BWK49_RS10365 8dd48046380341a18a21a727ef8f3384 270 SUPERFAMILY SSF52540 85 253 1.68E-25 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS10365 8dd48046380341a18a21a727ef8f3384 270 PIRSF PIRSF003073 19 270 8.4E-85 T 06-07-2017 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein BWK49_RS10365 8dd48046380341a18a21a727ef8f3384 270 SMART SM00382 116 230 9.8E-4 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS23330 9c667d364d54b6360d4240c10d1d0c03 159 Gene3D G3DSA:3.10.490.10 3 152 6.4E-49 T 06-07-2017 IPR013024 Butirosin biosynthesis, BtrG-like BWK49_RS23330 9c667d364d54b6360d4240c10d1d0c03 159 SUPERFAMILY SSF110857 3 125 1.57E-15 T 06-07-2017 IPR013024 Butirosin biosynthesis, BtrG-like BWK49_RS23330 9c667d364d54b6360d4240c10d1d0c03 159 Pfam PF13772 AIG2-like family 59 145 3.4E-25 T 06-07-2017 BWK49_RS14560 78a82300f7f83495e1fab6993e55e702 762 ProSitePatterns PS00161 Isocitrate lyase signature. 209 214 - T 06-07-2017 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824|GO:0008152 BWK49_RS14560 78a82300f7f83495e1fab6993e55e702 762 SUPERFAMILY SSF51621 422 596 3.85E-113 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 BWK49_RS14560 78a82300f7f83495e1fab6993e55e702 762 SUPERFAMILY SSF51621 12 271 3.85E-113 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 BWK49_RS14560 78a82300f7f83495e1fab6993e55e702 762 Pfam PF00463 Isocitrate lyase family 357 595 1.1E-46 T 06-07-2017 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 BWK49_RS14560 78a82300f7f83495e1fab6993e55e702 762 Pfam PF00463 Isocitrate lyase family 17 280 3.2E-73 T 06-07-2017 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 BWK49_RS14560 78a82300f7f83495e1fab6993e55e702 762 Gene3D G3DSA:3.20.20.60 14 271 4.1E-148 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 BWK49_RS14560 78a82300f7f83495e1fab6993e55e702 762 Gene3D G3DSA:3.20.20.60 422 578 4.1E-148 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 BWK49_RS04030 44ed31375d866c11ef156f554381ccce 357 SMART SM00587 117 290 0.0026 T 06-07-2017 IPR015897 CHK kinase-like BWK49_RS04030 44ed31375d866c11ef156f554381ccce 357 Gene3D G3DSA:3.90.1200.10 144 313 2.7E-19 T 06-07-2017 BWK49_RS04030 44ed31375d866c11ef156f554381ccce 357 SUPERFAMILY SSF56112 12 326 1.37E-38 T 06-07-2017 IPR011009 Protein kinase-like domain BWK49_RS04030 44ed31375d866c11ef156f554381ccce 357 Pfam PF01636 Phosphotransferase enzyme family 101 285 6.3E-11 T 06-07-2017 IPR002575 Aminoglycoside phosphotransferase BWK49_RS22045 115b2d92bd060b2e0f1bbc7147997113 633 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 117 137 3.0E-62 T 06-07-2017 BWK49_RS22045 115b2d92bd060b2e0f1bbc7147997113 633 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 89 114 3.0E-62 T 06-07-2017 BWK49_RS22045 115b2d92bd060b2e0f1bbc7147997113 633 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 229 250 3.0E-62 T 06-07-2017 BWK49_RS22045 115b2d92bd060b2e0f1bbc7147997113 633 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 319 331 3.0E-62 T 06-07-2017 BWK49_RS22045 115b2d92bd060b2e0f1bbc7147997113 633 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 426 445 3.0E-62 T 06-07-2017 BWK49_RS22045 115b2d92bd060b2e0f1bbc7147997113 633 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 251 277 3.0E-62 T 06-07-2017 BWK49_RS22045 115b2d92bd060b2e0f1bbc7147997113 633 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 164 185 3.0E-62 T 06-07-2017 BWK49_RS22045 115b2d92bd060b2e0f1bbc7147997113 633 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 425 447 3.3E-14 T 06-07-2017 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 BWK49_RS22045 115b2d92bd060b2e0f1bbc7147997113 633 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 91 111 3.3E-14 T 06-07-2017 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 BWK49_RS22045 115b2d92bd060b2e0f1bbc7147997113 633 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 269 291 3.3E-14 T 06-07-2017 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 BWK49_RS22045 115b2d92bd060b2e0f1bbc7147997113 633 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 502 523 3.3E-14 T 06-07-2017 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 BWK49_RS22045 115b2d92bd060b2e0f1bbc7147997113 633 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 65 89 3.3E-14 T 06-07-2017 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 BWK49_RS22045 115b2d92bd060b2e0f1bbc7147997113 633 Pfam PF00361 Proton-conducting membrane transporter 140 426 1.3E-83 T 06-07-2017 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS22045 115b2d92bd060b2e0f1bbc7147997113 633 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 71 128 3.2E-22 T 06-07-2017 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS22045 115b2d92bd060b2e0f1bbc7147997113 633 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 10 627 2.2E-235 T 06-07-2017 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS17395 644a64fa7d30df02d8803b598dcbe84e 120 Gene3D G3DSA:2.60.40.420 50 96 3.6E-4 T 06-07-2017 IPR008972 Cupredoxin BWK49_RS17395 644a64fa7d30df02d8803b598dcbe84e 120 SUPERFAMILY SSF49503 39 97 2.77E-5 T 06-07-2017 IPR008972 Cupredoxin BWK49_RS07485 a15085fa30722a71752ff3748aa95fde 219 ProSitePatterns PS01081 TetR-type HTH domain signature. 44 74 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site BWK49_RS07485 a15085fa30722a71752ff3748aa95fde 219 Pfam PF00440 Bacterial regulatory proteins, tetR family 35 76 4.3E-16 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS07485 a15085fa30722a71752ff3748aa95fde 219 SUPERFAMILY SSF46689 19 96 1.85E-19 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS07485 a15085fa30722a71752ff3748aa95fde 219 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 53 76 1.1E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS07485 a15085fa30722a71752ff3748aa95fde 219 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 45 1.1E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS07485 a15085fa30722a71752ff3748aa95fde 219 SUPERFAMILY SSF48498 101 207 2.22E-7 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS07485 a15085fa30722a71752ff3748aa95fde 219 Gene3D G3DSA:1.10.357.10 17 207 7.0E-42 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS14650 85bc4e9b122b3a3f8b1a58918bd9d198 415 ProSitePatterns PS00217 Sugar transport proteins signature 2. 104 129 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 BWK49_RS14650 85bc4e9b122b3a3f8b1a58918bd9d198 415 Gene3D G3DSA:1.20.1250.20 213 395 3.0E-20 T 06-07-2017 BWK49_RS14650 85bc4e9b122b3a3f8b1a58918bd9d198 415 SUPERFAMILY SSF103473 7 396 2.62E-68 T 06-07-2017 IPR020846 Major facilitator superfamily domain BWK49_RS14650 85bc4e9b122b3a3f8b1a58918bd9d198 415 Pfam PF07690 Major Facilitator Superfamily 17 252 4.9E-27 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 BWK49_RS14650 85bc4e9b122b3a3f8b1a58918bd9d198 415 Gene3D G3DSA:1.20.1250.20 8 194 1.4E-33 T 06-07-2017 BWK49_RS16820 a386a9c19b3aefb10aad9c3fce173fb5 374 Gene3D G3DSA:3.20.20.70 5 372 9.9E-132 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 BWK49_RS16820 a386a9c19b3aefb10aad9c3fce173fb5 374 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 6 351 1.3E-86 T 06-07-2017 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 BWK49_RS16820 a386a9c19b3aefb10aad9c3fce173fb5 374 SUPERFAMILY SSF51395 2 372 2.44E-123 T 06-07-2017 BWK49_RS17555 c4ec1bf551539e63b372a5b1f8bb4aa9 252 Pfam PF08241 Methyltransferase domain 53 140 5.8E-6 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 BWK49_RS17555 c4ec1bf551539e63b372a5b1f8bb4aa9 252 Gene3D G3DSA:3.40.50.150 51 251 2.7E-18 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS17555 c4ec1bf551539e63b372a5b1f8bb4aa9 252 SUPERFAMILY SSF53335 20 251 2.44E-20 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS21575 71ae95052acad27ba2111698ca88d0b0 481 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 248 255 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 BWK49_RS21575 71ae95052acad27ba2111698ca88d0b0 481 SUPERFAMILY SSF53720 16 477 9.82E-156 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 BWK49_RS21575 71ae95052acad27ba2111698ca88d0b0 481 Gene3D G3DSA:3.40.605.10 18 261 6.9E-83 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 BWK49_RS21575 71ae95052acad27ba2111698ca88d0b0 481 Pfam PF00171 Aldehyde dehydrogenase family 22 475 2.8E-157 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 BWK49_RS21575 71ae95052acad27ba2111698ca88d0b0 481 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 276 287 - T 06-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 BWK49_RS21575 71ae95052acad27ba2111698ca88d0b0 481 Gene3D G3DSA:3.40.309.10 262 450 9.6E-66 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 BWK49_RS24515 b88c3d734e2904dc4926e7f1d629df5b 207 Pfam PF00466 Ribosomal protein L10 1 98 3.9E-26 T 06-07-2017 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 BWK49_RS24515 b88c3d734e2904dc4926e7f1d629df5b 207 ProSitePatterns PS01109 Ribosomal protein L10 signature. 6 40 - T 06-07-2017 IPR002363 Ribosomal protein L10, eubacterial, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS24515 b88c3d734e2904dc4926e7f1d629df5b 207 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 1 158 25.322 T 06-07-2017 IPR022973 Ribosomal protein L10 BWK49_RS24515 b88c3d734e2904dc4926e7f1d629df5b 207 SUPERFAMILY SSF160369 1 169 7.98E-49 T 06-07-2017 BWK49_RS14495 57c64794065b9997716ec88363c04a8c 164 Hamap MF_00269 Probable thiol peroxidase [tpx]. 3 164 38.089 T 06-07-2017 IPR002065 Putative thiol peroxidase Tpx GO:0008379|GO:0016209|GO:0055114 BWK49_RS14495 57c64794065b9997716ec88363c04a8c 164 SUPERFAMILY SSF52833 1 161 1.46E-41 T 06-07-2017 IPR012336 Thioredoxin-like fold BWK49_RS14495 57c64794065b9997716ec88363c04a8c 164 ProSitePatterns PS01265 Tpx family signature. 82 93 - T 06-07-2017 IPR018219 Thiol peroxidase conserved site GO:0016684|GO:0055114 BWK49_RS14495 57c64794065b9997716ec88363c04a8c 164 Pfam PF08534 Redoxin 20 160 2.6E-25 T 06-07-2017 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 BWK49_RS14495 57c64794065b9997716ec88363c04a8c 164 Gene3D G3DSA:3.40.30.10 2 163 2.1E-47 T 06-07-2017 IPR012336 Thioredoxin-like fold BWK49_RS21795 746fae12244e0a31984733f1f5e689f4 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 73 1.6E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS21795 746fae12244e0a31984733f1f5e689f4 200 SUPERFAMILY SSF46689 14 88 8.72E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS21795 746fae12244e0a31984733f1f5e689f4 200 Gene3D G3DSA:1.10.357.10 16 198 3.3E-25 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS28075 813fdbbe1f83ca51115f6c087cd100ed 186 Pfam PF13977 Bacterial transcriptional repressor 92 178 8.2E-7 T 06-07-2017 BWK49_RS28075 813fdbbe1f83ca51115f6c087cd100ed 186 SUPERFAMILY SSF48498 88 173 2.4E-5 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS28075 813fdbbe1f83ca51115f6c087cd100ed 186 Pfam PF00440 Bacterial regulatory proteins, tetR family 1 40 5.0E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS28075 813fdbbe1f83ca51115f6c087cd100ed 186 SUPERFAMILY SSF46689 2 48 4.21E-6 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS28075 813fdbbe1f83ca51115f6c087cd100ed 186 Gene3D G3DSA:1.10.357.10 2 180 8.8E-21 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS01220 9421269bcd6c2f3a5ee5435de1e83ce0 162 Gene3D G3DSA:3.30.530.20 3 158 5.8E-16 T 06-07-2017 IPR023393 START-like domain BWK49_RS01220 9421269bcd6c2f3a5ee5435de1e83ce0 162 SUPERFAMILY SSF55961 6 157 4.69E-40 T 06-07-2017 BWK49_RS01220 9421269bcd6c2f3a5ee5435de1e83ce0 162 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 16 151 7.9E-9 T 06-07-2017 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 BWK49_RS02775 c421c7c725400701b9cf52174ef2f463 263 Pfam PF00753 Metallo-beta-lactamase superfamily 36 193 1.4E-10 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS02775 c421c7c725400701b9cf52174ef2f463 263 Gene3D G3DSA:3.60.15.10 11 224 4.7E-42 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS02775 c421c7c725400701b9cf52174ef2f463 263 SUPERFAMILY SSF56281 16 262 1.12E-45 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS02775 c421c7c725400701b9cf52174ef2f463 263 SMART SM00849 38 193 8.9E-26 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS04150 431c056040a028af0cd3a106fb55e9c1 222 SUPERFAMILY SSF109755 2 215 8.06E-54 T 06-07-2017 BWK49_RS04150 431c056040a028af0cd3a106fb55e9c1 222 Gene3D G3DSA:1.20.58.220 111 210 3.4E-18 T 06-07-2017 BWK49_RS04150 431c056040a028af0cd3a106fb55e9c1 222 Gene3D G3DSA:1.20.58.220 1 106 2.8E-23 T 06-07-2017 BWK49_RS04150 431c056040a028af0cd3a106fb55e9c1 222 Pfam PF01895 PhoU domain 122 204 3.9E-11 T 06-07-2017 IPR026022 PhoU domain BWK49_RS04150 431c056040a028af0cd3a106fb55e9c1 222 Pfam PF01895 PhoU domain 17 103 1.2E-11 T 06-07-2017 IPR026022 PhoU domain BWK49_RS04150 431c056040a028af0cd3a106fb55e9c1 222 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 4 211 8.4E-60 T 06-07-2017 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 BWK49_RS04150 431c056040a028af0cd3a106fb55e9c1 222 PIRSF PIRSF003107 1 218 1.3E-49 T 06-07-2017 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 BWK49_RS27325 42db0e4ad03dff23d71c111ecb409175 252 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 30 237 3.2E-31 T 06-07-2017 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 BWK49_RS27325 42db0e4ad03dff23d71c111ecb409175 252 Gene3D G3DSA:3.20.20.60 8 250 1.8E-57 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 BWK49_RS27325 42db0e4ad03dff23d71c111ecb409175 252 SUPERFAMILY SSF51621 9 250 3.45E-60 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 BWK49_RS14440 a44a73cf4d1ee9d4bb59dbb93c56d81e 281 Pfam PF04072 Leucine carboxyl methyltransferase 17 182 2.0E-30 T 06-07-2017 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 BWK49_RS14440 a44a73cf4d1ee9d4bb59dbb93c56d81e 281 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 13 240 5.5E-36 T 06-07-2017 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 BWK49_RS14440 a44a73cf4d1ee9d4bb59dbb93c56d81e 281 Gene3D G3DSA:3.40.50.150 18 208 1.2E-22 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS14440 a44a73cf4d1ee9d4bb59dbb93c56d81e 281 SUPERFAMILY SSF53335 11 255 7.56E-51 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS27150 31c17fa51be84ca7d6f68cf2aebae956 218 SUPERFAMILY SSF53335 5 214 3.19E-41 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS27150 31c17fa51be84ca7d6f68cf2aebae956 218 Gene3D G3DSA:3.40.50.150 4 217 1.2E-62 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS27150 31c17fa51be84ca7d6f68cf2aebae956 218 Pfam PF01596 O-methyltransferase 33 200 1.8E-33 T 06-07-2017 IPR002935 O-methyltransferase, family 3 GO:0008171 BWK49_RS25230 072e16d978355606ace339111291096b 432 Pfam PF01757 Acyltransferase family 31 382 2.2E-27 T 06-07-2017 IPR002656 Acyltransferase 3 GO:0016747 BWK49_RS17405 33b589ba14fc7780676532a11eb98527 727 SMART SM00304 463 515 5.4E-16 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 BWK49_RS17405 33b589ba14fc7780676532a11eb98527 727 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 548 718 2.1E-32 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 BWK49_RS17405 33b589ba14fc7780676532a11eb98527 727 SUPERFAMILY SSF158472 465 511 3.14E-11 T 06-07-2017 BWK49_RS17405 33b589ba14fc7780676532a11eb98527 727 Gene3D G3DSA:3.30.70.1230 542 720 2.5E-40 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 BWK49_RS17405 33b589ba14fc7780676532a11eb98527 727 Pfam PF00672 HAMP domain 444 511 1.3E-17 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 BWK49_RS17405 33b589ba14fc7780676532a11eb98527 727 SMART SM00044 519 710 1.6E-25 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 BWK49_RS17405 33b589ba14fc7780676532a11eb98527 727 SUPERFAMILY SSF55073 541 721 6.59E-42 T 06-07-2017 IPR029787 Nucleotide cyclase BWK49_RS26685 e91d22790079a9802341aab866fcd002 335 Gene3D G3DSA:2.60.120.330 5 290 7.4E-78 T 06-07-2017 IPR027443 Isopenicillin N synthase-like BWK49_RS26685 e91d22790079a9802341aab866fcd002 335 Pfam PF14226 non-haem dioxygenase in morphine synthesis N-terminal 7 123 4.0E-31 T 06-07-2017 IPR026992 Non-haem dioxygenase N-terminal domain BWK49_RS26685 e91d22790079a9802341aab866fcd002 335 Pfam PF03171 2OG-Fe(II) oxygenase superfamily 185 270 1.2E-15 T 06-07-2017 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 BWK49_RS26685 e91d22790079a9802341aab866fcd002 335 PRINTS PR00682 Isopenicillin N synthase signature 23 40 2.4E-7 T 06-07-2017 IPR002283 Isopenicillin N synthase GO:0005506|GO:0016491|GO:0055114 BWK49_RS26685 e91d22790079a9802341aab866fcd002 335 PRINTS PR00682 Isopenicillin N synthase signature 258 276 2.4E-7 T 06-07-2017 IPR002283 Isopenicillin N synthase GO:0005506|GO:0016491|GO:0055114 BWK49_RS26685 e91d22790079a9802341aab866fcd002 335 PRINTS PR00682 Isopenicillin N synthase signature 145 161 2.4E-7 T 06-07-2017 IPR002283 Isopenicillin N synthase GO:0005506|GO:0016491|GO:0055114 BWK49_RS26685 e91d22790079a9802341aab866fcd002 335 SUPERFAMILY SSF51197 4 277 3.64E-71 T 06-07-2017 BWK49_RS26990 45a4a7ab1f04a697894aadbe67e5b80f 242 SUPERFAMILY SSF53474 3 240 1.18E-52 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS26990 45a4a7ab1f04a697894aadbe67e5b80f 242 Gene3D G3DSA:3.40.50.1820 5 240 7.3E-53 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS26990 45a4a7ab1f04a697894aadbe67e5b80f 242 Pfam PF00561 alpha/beta hydrolase fold 5 229 1.6E-24 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS26990 45a4a7ab1f04a697894aadbe67e5b80f 242 PRINTS PR00111 Alpha/beta hydrolase fold signature 186 200 3.0E-13 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS26990 45a4a7ab1f04a697894aadbe67e5b80f 242 PRINTS PR00111 Alpha/beta hydrolase fold signature 22 37 3.0E-13 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS26990 45a4a7ab1f04a697894aadbe67e5b80f 242 PRINTS PR00111 Alpha/beta hydrolase fold signature 66 79 3.0E-13 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS26990 45a4a7ab1f04a697894aadbe67e5b80f 242 PRINTS PR00111 Alpha/beta hydrolase fold signature 80 93 3.0E-13 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS26990 45a4a7ab1f04a697894aadbe67e5b80f 242 PRINTS PR00412 Epoxide hydrolase signature 217 239 2.3E-6 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS26990 45a4a7ab1f04a697894aadbe67e5b80f 242 PRINTS PR00412 Epoxide hydrolase signature 66 79 2.3E-6 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS26990 45a4a7ab1f04a697894aadbe67e5b80f 242 PRINTS PR00412 Epoxide hydrolase signature 80 93 2.3E-6 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS26990 45a4a7ab1f04a697894aadbe67e5b80f 242 PRINTS PR00412 Epoxide hydrolase signature 22 37 2.3E-6 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS10885 2915ca350598fa646850c15db3627ed6 401 Pfam PF13469 Sulfotransferase family 95 347 3.5E-45 T 06-07-2017 BWK49_RS10885 2915ca350598fa646850c15db3627ed6 401 SUPERFAMILY SSF52540 91 130 5.67E-27 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS10885 2915ca350598fa646850c15db3627ed6 401 SUPERFAMILY SSF52540 192 373 5.67E-27 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS10885 2915ca350598fa646850c15db3627ed6 401 Gene3D G3DSA:3.40.50.300 96 131 5.3E-10 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS10885 2915ca350598fa646850c15db3627ed6 401 Gene3D G3DSA:3.40.50.300 206 353 5.3E-10 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS20930 f0e61fcee2503c0a684af7d85369e396 200 TIGRFAM TIGR01755 flav_wrbA: NAD(P)H:quinone oxidoreductase, type IV 2 171 1.4E-44 T 06-07-2017 IPR010089 Flavoprotein WrbA GO:0010181|GO:0045892 KEGG: 00130+1.6.5.2|MetaCyc: PWY-7731 BWK49_RS20930 f0e61fcee2503c0a684af7d85369e396 200 Gene3D G3DSA:3.40.50.360 2 198 1.2E-64 T 06-07-2017 IPR029039 Flavoprotein-like domain BWK49_RS20930 f0e61fcee2503c0a684af7d85369e396 200 Pfam PF03358 NADPH-dependent FMN reductase 3 147 2.6E-15 T 06-07-2017 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 BWK49_RS20930 f0e61fcee2503c0a684af7d85369e396 200 SUPERFAMILY SSF52218 3 197 1.7E-51 T 06-07-2017 IPR029039 Flavoprotein-like domain BWK49_RS21285 fe4fd4cd5d64401003498016e267f078 372 Gene3D G3DSA:3.40.50.1980 95 202 2.3E-24 T 06-07-2017 BWK49_RS21285 fe4fd4cd5d64401003498016e267f078 372 Pfam PF01497 Periplasmic binding protein 105 344 2.4E-14 T 06-07-2017 IPR002491 ABC transporter periplasmic binding domain GO:0005488 BWK49_RS21285 fe4fd4cd5d64401003498016e267f078 372 SUPERFAMILY SSF53807 95 354 1.45E-41 T 06-07-2017 BWK49_RS21285 fe4fd4cd5d64401003498016e267f078 372 Gene3D G3DSA:3.40.50.1980 203 364 3.3E-18 T 06-07-2017 BWK49_RS02125 10c6b32e51eee522938101935dba9a94 207 Gene3D G3DSA:1.10.357.10 20 205 1.6E-26 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS02125 10c6b32e51eee522938101935dba9a94 207 SUPERFAMILY SSF46689 20 101 1.7E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS02125 10c6b32e51eee522938101935dba9a94 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 31 77 7.3E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS01740 7ff7f73d181fb89f5f32bf1a131bfbab 466 Pfam PF00355 Rieske [2Fe-2S] domain 49 132 1.5E-20 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS01740 7ff7f73d181fb89f5f32bf1a131bfbab 466 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 63 78 9.7E-43 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS01740 7ff7f73d181fb89f5f32bf1a131bfbab 466 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 105 125 9.7E-43 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS01740 7ff7f73d181fb89f5f32bf1a131bfbab 466 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 149 175 9.7E-43 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS01740 7ff7f73d181fb89f5f32bf1a131bfbab 466 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 84 104 9.7E-43 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS01740 7ff7f73d181fb89f5f32bf1a131bfbab 466 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 190 212 9.7E-43 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS01740 7ff7f73d181fb89f5f32bf1a131bfbab 466 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 33 58 9.7E-43 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS01740 7ff7f73d181fb89f5f32bf1a131bfbab 466 Gene3D G3DSA:2.102.10.10 49 154 1.2E-24 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS01740 7ff7f73d181fb89f5f32bf1a131bfbab 466 ProSitePatterns PS00570 Bacterial ring hydroxylating dioxygenases alpha-subunit signature. 91 114 - T 06-07-2017 IPR015881 Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site GO:0005506|GO:0016705|GO:0051537|GO:0055114 BWK49_RS01740 7ff7f73d181fb89f5f32bf1a131bfbab 466 SUPERFAMILY SSF55961 166 441 1.1E-69 T 06-07-2017 BWK49_RS01740 7ff7f73d181fb89f5f32bf1a131bfbab 466 SUPERFAMILY SSF50022 25 164 1.7E-46 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS01740 7ff7f73d181fb89f5f32bf1a131bfbab 466 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 170 438 1.3E-22 T 06-07-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 BWK49_RS01740 7ff7f73d181fb89f5f32bf1a131bfbab 466 Gene3D G3DSA:3.90.380.10 155 446 3.8E-99 T 06-07-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 BWK49_RS04125 7e9f24771c75b4e94c71273a8411d5cc 308 PIRSF PIRSF021524 3 307 1.6E-98 T 06-07-2017 IPR017813 Mycothiol acetyltransferase GO:0016747 BWK49_RS04125 7e9f24771c75b4e94c71273a8411d5cc 308 Gene3D G3DSA:3.40.630.30 151 301 2.3E-26 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase BWK49_RS04125 7e9f24771c75b4e94c71273a8411d5cc 308 SUPERFAMILY SSF55729 5 300 7.43E-44 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase BWK49_RS04125 7e9f24771c75b4e94c71273a8411d5cc 308 Pfam PF00583 Acetyltransferase (GNAT) family 212 293 9.0E-14 T 06-07-2017 IPR000182 GNAT domain GO:0008080 BWK49_RS04125 7e9f24771c75b4e94c71273a8411d5cc 308 Pfam PF00583 Acetyltransferase (GNAT) family 55 118 5.3E-9 T 06-07-2017 IPR000182 GNAT domain GO:0008080 BWK49_RS04125 7e9f24771c75b4e94c71273a8411d5cc 308 TIGRFAM TIGR03448 mycothiol_MshD: mycothiol synthase 4 301 3.7E-128 T 06-07-2017 IPR017813 Mycothiol acetyltransferase GO:0016747 BWK49_RS04125 7e9f24771c75b4e94c71273a8411d5cc 308 Gene3D G3DSA:3.40.630.30 7 104 2.0E-11 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase BWK49_RS04125 7e9f24771c75b4e94c71273a8411d5cc 308 Hamap MF_01698 Mycothiol acetyltransferase [mshD]. 8 303 35.118 T 06-07-2017 IPR017813 Mycothiol acetyltransferase GO:0016747 BWK49_RS15390 d753d18eef84356a6114a15ca059a3c1 290 SUPERFAMILY SSF52096 7 266 3.87E-56 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS15390 d753d18eef84356a6114a15ca059a3c1 290 Gene3D G3DSA:3.90.226.10 5 259 9.7E-53 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS15390 d753d18eef84356a6114a15ca059a3c1 290 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 114 134 - T 06-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 BWK49_RS15390 d753d18eef84356a6114a15ca059a3c1 290 Pfam PF00378 Enoyl-CoA hydratase/isomerase 16 236 6.0E-31 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 BWK49_RS20200 817329e7b6aae5615c75aca9dcea8ef8 280 SUPERFAMILY SSF52313 6 229 1.83E-94 T 06-07-2017 IPR023591 Ribosomal protein S2, flavodoxin-like domain BWK49_RS20200 817329e7b6aae5615c75aca9dcea8ef8 280 Pfam PF00318 Ribosomal protein S2 9 224 5.5E-97 T 06-07-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS20200 817329e7b6aae5615c75aca9dcea8ef8 280 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 2 233 42.381 T 06-07-2017 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 BWK49_RS20200 817329e7b6aae5615c75aca9dcea8ef8 280 PRINTS PR00395 Ribosomal protein S2 signature 175 186 4.3E-39 T 06-07-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS20200 817329e7b6aae5615c75aca9dcea8ef8 280 PRINTS PR00395 Ribosomal protein S2 signature 87 104 4.3E-39 T 06-07-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS20200 817329e7b6aae5615c75aca9dcea8ef8 280 PRINTS PR00395 Ribosomal protein S2 signature 37 46 4.3E-39 T 06-07-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS20200 817329e7b6aae5615c75aca9dcea8ef8 280 PRINTS PR00395 Ribosomal protein S2 signature 196 210 4.3E-39 T 06-07-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS20200 817329e7b6aae5615c75aca9dcea8ef8 280 PRINTS PR00395 Ribosomal protein S2 signature 6 24 4.3E-39 T 06-07-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS20200 817329e7b6aae5615c75aca9dcea8ef8 280 PRINTS PR00395 Ribosomal protein S2 signature 158 175 4.3E-39 T 06-07-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS20200 817329e7b6aae5615c75aca9dcea8ef8 280 Gene3D G3DSA:1.10.287.610 100 152 1.7E-24 T 06-07-2017 BWK49_RS20200 817329e7b6aae5615c75aca9dcea8ef8 280 Gene3D G3DSA:3.40.50.10490 158 243 3.8E-68 T 06-07-2017 BWK49_RS20200 817329e7b6aae5615c75aca9dcea8ef8 280 Gene3D G3DSA:3.40.50.10490 23 99 3.8E-68 T 06-07-2017 BWK49_RS20200 817329e7b6aae5615c75aca9dcea8ef8 280 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 3 226 5.7E-111 T 06-07-2017 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 BWK49_RS20200 817329e7b6aae5615c75aca9dcea8ef8 280 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 6 17 - T 06-07-2017 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 BWK49_RS02415 36423cb5774c5506238a7cc4f4ffd81f 128 SUPERFAMILY SSF50475 11 117 5.05E-19 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 BWK49_RS02415 36423cb5774c5506238a7cc4f4ffd81f 128 TIGRFAM TIGR03666 Rv2061_F420: PPOX class probable F420-dependent enzyme, Rv2061 family 1 128 1.0E-43 T 06-07-2017 IPR019965 PPOX class F420-dependent enzyme, family Rv2061, putative BWK49_RS02415 36423cb5774c5506238a7cc4f4ffd81f 128 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 8 62 3.8E-9 T 06-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 BWK49_RS02415 36423cb5774c5506238a7cc4f4ffd81f 128 Gene3D G3DSA:2.30.110.10 11 107 3.8E-14 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 BWK49_RS18740 e185eda32a9df9c7406f722604a323a2 99 Gene3D G3DSA:3.40.50.2000 3 78 1.4E-6 T 06-07-2017 BWK49_RS03350 1010d6c5fbcce3af3d33f8359a8db0f8 215 Gene3D G3DSA:1.10.10.10 158 196 0.001 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS03350 1010d6c5fbcce3af3d33f8359a8db0f8 215 Pfam PF16264 SatD family (SatD) 13 201 2.7E-14 T 06-07-2017 IPR032580 SatD family BWK49_RS23080 ad2ea115a8abcb8e2c18b95ef6f747ed 661 Gene3D G3DSA:3.30.200.20 14 81 4.4E-19 T 06-07-2017 BWK49_RS23080 ad2ea115a8abcb8e2c18b95ef6f747ed 661 Gene3D G3DSA:1.10.510.10 82 280 4.7E-41 T 06-07-2017 BWK49_RS23080 ad2ea115a8abcb8e2c18b95ef6f747ed 661 SUPERFAMILY SSF101898 422 659 2.88E-44 T 06-07-2017 BWK49_RS23080 ad2ea115a8abcb8e2c18b95ef6f747ed 661 Gene3D G3DSA:2.120.10.30 423 660 4.2E-55 T 06-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like BWK49_RS23080 ad2ea115a8abcb8e2c18b95ef6f747ed 661 SUPERFAMILY SSF56112 14 308 1.75E-65 T 06-07-2017 IPR011009 Protein kinase-like domain BWK49_RS23080 ad2ea115a8abcb8e2c18b95ef6f747ed 661 Pfam PF01436 NHL repeat 549 574 3.1E-6 T 06-07-2017 IPR001258 NHL repeat GO:0005515 BWK49_RS23080 ad2ea115a8abcb8e2c18b95ef6f747ed 661 Pfam PF01436 NHL repeat 465 486 2.5E-4 T 06-07-2017 IPR001258 NHL repeat GO:0005515 BWK49_RS23080 ad2ea115a8abcb8e2c18b95ef6f747ed 661 Pfam PF01436 NHL repeat 506 532 2.3E-8 T 06-07-2017 IPR001258 NHL repeat GO:0005515 BWK49_RS23080 ad2ea115a8abcb8e2c18b95ef6f747ed 661 Pfam PF00069 Protein kinase domain 18 264 1.6E-38 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 BWK49_RS23080 ad2ea115a8abcb8e2c18b95ef6f747ed 661 ProSitePatterns PS00109 Tyrosine protein kinases specific active-site signature. 136 148 - T 06-07-2017 IPR008266 Tyrosine-protein kinase, active site GO:0004672|GO:0006468 BWK49_RS19390 9ca7a8511083aef179b8118fb6fa71ae 257 Pfam PF12502 Protein of unknown function (DUF3710) 39 208 6.8E-56 T 06-07-2017 IPR022183 Protein of unknown function DUF3710 BWK49_RS14165 d6e242ebc1ab61c0549e4ffb3b8f55c0 418 Pfam PF00823 PPE family 5 160 6.4E-65 T 06-07-2017 IPR000030 PPE family BWK49_RS14165 d6e242ebc1ab61c0549e4ffb3b8f55c0 418 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 315 387 1.3E-9 T 06-07-2017 IPR022171 PPE family, C-terminal BWK49_RS14165 d6e242ebc1ab61c0549e4ffb3b8f55c0 418 SUPERFAMILY SSF140459 3 172 1.86E-66 T 06-07-2017 BWK49_RS24720 1be8a89fb7f698f649ddb67682ac4750 792 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 490 779 2.7E-30 T 06-07-2017 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD BWK49_RS00865 9b2ef6bda941f0cbe9f799be7e349c57 276 Pfam PF14011 EspG family 5 257 2.4E-33 T 06-07-2017 IPR025734 EspG family BWK49_RS17045 4f52a7807b45cf9080ec39400233ed66 622 SMART SM00065 23 174 6.0E-16 T 06-07-2017 IPR003018 GAF domain GO:0005515 BWK49_RS17045 4f52a7807b45cf9080ec39400233ed66 622 SMART SM00052 347 596 1.4E-97 T 06-07-2017 IPR001633 EAL domain BWK49_RS17045 4f52a7807b45cf9080ec39400233ed66 622 Gene3D G3DSA:3.30.450.40 19 173 2.9E-11 T 06-07-2017 IPR029016 GAF domain-like BWK49_RS17045 4f52a7807b45cf9080ec39400233ed66 622 Gene3D G3DSA:3.30.70.270 178 343 1.4E-41 T 06-07-2017 BWK49_RS17045 4f52a7807b45cf9080ec39400233ed66 622 SUPERFAMILY SSF141868 364 604 2.88E-78 T 06-07-2017 IPR001633 EAL domain BWK49_RS17045 4f52a7807b45cf9080ec39400233ed66 622 SUPERFAMILY SSF55781 26 176 2.62E-14 T 06-07-2017 IPR029016 GAF domain-like BWK49_RS17045 4f52a7807b45cf9080ec39400233ed66 622 Gene3D G3DSA:3.20.20.450 364 603 2.5E-82 T 06-07-2017 IPR001633 EAL domain BWK49_RS17045 4f52a7807b45cf9080ec39400233ed66 622 SMART SM00267 166 337 2.9E-44 T 06-07-2017 IPR000160 GGDEF domain BWK49_RS17045 4f52a7807b45cf9080ec39400233ed66 622 Pfam PF01590 GAF domain 26 162 4.5E-8 T 06-07-2017 IPR003018 GAF domain GO:0005515 BWK49_RS17045 4f52a7807b45cf9080ec39400233ed66 622 Pfam PF00563 EAL domain 364 591 1.8E-62 T 06-07-2017 IPR001633 EAL domain BWK49_RS17045 4f52a7807b45cf9080ec39400233ed66 622 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 176 335 6.4E-30 T 06-07-2017 IPR000160 GGDEF domain BWK49_RS17045 4f52a7807b45cf9080ec39400233ed66 622 Pfam PF00990 Diguanylate cyclase, GGDEF domain 177 333 7.8E-33 T 06-07-2017 IPR000160 GGDEF domain BWK49_RS17045 4f52a7807b45cf9080ec39400233ed66 622 SUPERFAMILY SSF55073 182 339 5.97E-34 T 06-07-2017 IPR029787 Nucleotide cyclase BWK49_RS23520 b9b80c9f74e64c91557d1806fd69c5ba 382 Gene3D G3DSA:3.40.50.1820 32 368 2.9E-31 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS23520 b9b80c9f74e64c91557d1806fd69c5ba 382 TIGRFAM TIGR01392 homoserO_Ac_trn: homoserine O-acetyltransferase 24 368 1.5E-128 T 06-07-2017 IPR008220 Homoserine acetyltransferase GO:0004414|GO:0005737|GO:0009086 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 BWK49_RS23520 b9b80c9f74e64c91557d1806fd69c5ba 382 Pfam PF00561 alpha/beta hydrolase fold 52 356 2.7E-29 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS23520 b9b80c9f74e64c91557d1806fd69c5ba 382 Hamap MF_00296 Homoserine O-acetyltransferase [metX]. 9 370 45.652 T 06-07-2017 IPR008220 Homoserine acetyltransferase GO:0004414|GO:0005737|GO:0009086 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 BWK49_RS23520 b9b80c9f74e64c91557d1806fd69c5ba 382 SUPERFAMILY SSF53474 18 366 9.15E-88 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS23520 b9b80c9f74e64c91557d1806fd69c5ba 382 PIRSF PIRSF000443 2 375 4.7E-108 T 06-07-2017 IPR008220 Homoserine acetyltransferase GO:0004414|GO:0005737|GO:0009086 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 BWK49_RS07720 beb804bd77d4b900c37eff1d7ece7008 355 Pfam PF07859 alpha/beta hydrolase fold 124 330 2.1E-42 T 06-07-2017 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 BWK49_RS07720 beb804bd77d4b900c37eff1d7ece7008 355 SUPERFAMILY SSF53474 79 352 7.9E-48 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS07720 beb804bd77d4b900c37eff1d7ece7008 355 ProSitePatterns PS01174 Lipolytic enzymes "G-D-X-G" family, putative serine active site. 192 204 - T 06-07-2017 IPR033140 Lipase, GDXG, putative serine active site BWK49_RS07720 beb804bd77d4b900c37eff1d7ece7008 355 Gene3D G3DSA:3.40.50.1820 109 352 6.0E-53 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS06445 30e345c5d6c508ea7a47336b3fc78035 396 SUPERFAMILY SSF51556 12 41 1.11E-61 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS06445 30e345c5d6c508ea7a47336b3fc78035 396 SUPERFAMILY SSF51556 96 393 1.11E-61 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS06445 30e345c5d6c508ea7a47336b3fc78035 396 Gene3D G3DSA:3.20.20.140 14 41 1.2E-54 T 06-07-2017 BWK49_RS06445 30e345c5d6c508ea7a47336b3fc78035 396 Gene3D G3DSA:3.20.20.140 82 393 1.2E-54 T 06-07-2017 BWK49_RS06445 30e345c5d6c508ea7a47336b3fc78035 396 Pfam PF04909 Amidohydrolase 103 389 4.9E-25 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 BWK49_RS13480 877b055f6f187302a4069b1eb127b631 136 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 8 92 8.6E-12 T 06-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 BWK49_RS13480 877b055f6f187302a4069b1eb127b631 136 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 13 127 4.9E-28 T 06-07-2017 IPR019920 F420-binding domain, putative BWK49_RS13480 877b055f6f187302a4069b1eb127b631 136 Gene3D G3DSA:2.30.110.10 8 127 8.7E-29 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 BWK49_RS13480 877b055f6f187302a4069b1eb127b631 136 SUPERFAMILY SSF50475 9 127 2.14E-32 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 BWK49_RS09365 3ad3492e67cfa24b6c59cff8bf242e28 401 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 343 352 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 BWK49_RS09365 3ad3492e67cfa24b6c59cff8bf242e28 401 PRINTS PR00385 P450 superfamily signature 238 255 3.8E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS09365 3ad3492e67cfa24b6c59cff8bf242e28 401 PRINTS PR00385 P450 superfamily signature 341 350 3.8E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS09365 3ad3492e67cfa24b6c59cff8bf242e28 401 PRINTS PR00385 P450 superfamily signature 273 284 3.8E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS09365 3ad3492e67cfa24b6c59cff8bf242e28 401 PRINTS PR00385 P450 superfamily signature 350 361 3.8E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS09365 3ad3492e67cfa24b6c59cff8bf242e28 401 Pfam PF00067 Cytochrome P450 37 370 1.9E-29 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS09365 3ad3492e67cfa24b6c59cff8bf242e28 401 Gene3D G3DSA:1.10.630.10 8 399 4.5E-111 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS09365 3ad3492e67cfa24b6c59cff8bf242e28 401 SUPERFAMILY SSF48264 13 401 1.14E-89 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS09365 3ad3492e67cfa24b6c59cff8bf242e28 401 PRINTS PR00359 B-class P450 signature 187 209 1.4E-49 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS09365 3ad3492e67cfa24b6c59cff8bf242e28 401 PRINTS PR00359 B-class P450 signature 273 284 1.4E-49 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS09365 3ad3492e67cfa24b6c59cff8bf242e28 401 PRINTS PR00359 B-class P450 signature 290 317 1.4E-49 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS09365 3ad3492e67cfa24b6c59cff8bf242e28 401 PRINTS PR00359 B-class P450 signature 341 350 1.4E-49 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS09365 3ad3492e67cfa24b6c59cff8bf242e28 401 PRINTS PR00359 B-class P450 signature 84 95 1.4E-49 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS09365 3ad3492e67cfa24b6c59cff8bf242e28 401 PRINTS PR00359 B-class P450 signature 129 145 1.4E-49 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS09365 3ad3492e67cfa24b6c59cff8bf242e28 401 PRINTS PR00359 B-class P450 signature 146 161 1.4E-49 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS09365 3ad3492e67cfa24b6c59cff8bf242e28 401 PRINTS PR00359 B-class P450 signature 350 361 1.4E-49 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS09365 3ad3492e67cfa24b6c59cff8bf242e28 401 PRINTS PR00359 B-class P450 signature 318 333 1.4E-49 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS23450 8440b461ec4d84f72708930523ae56ea 164 SUPERFAMILY SSF50475 42 135 1.75E-12 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 BWK49_RS23450 8440b461ec4d84f72708930523ae56ea 164 TIGRFAM TIGR03666 Rv2061_F420: PPOX class probable F420-dependent enzyme, Rv2061 family 36 162 1.6E-36 T 06-07-2017 IPR019965 PPOX class F420-dependent enzyme, family Rv2061, putative BWK49_RS23450 8440b461ec4d84f72708930523ae56ea 164 Gene3D G3DSA:2.30.110.10 42 132 1.6E-9 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 BWK49_RS23450 8440b461ec4d84f72708930523ae56ea 164 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 48 119 9.8E-5 T 06-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 BWK49_RS06460 ccaa1d344f330ac2ca6d9c99941a491b 61 Pfam PF04324 BFD-like [2Fe-2S] binding domain 3 50 4.4E-12 T 06-07-2017 IPR007419 BFD-like [2Fe-2S]-binding domain BWK49_RS07575 cc915db3c0153e7cbdce724a0f6a69df 511 Pfam PF00512 His Kinase A (phospho-acceptor) domain 278 344 2.2E-17 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 BWK49_RS07575 cc915db3c0153e7cbdce724a0f6a69df 511 Pfam PF00672 HAMP domain 188 264 5.6E-11 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 BWK49_RS07575 cc915db3c0153e7cbdce724a0f6a69df 511 Gene3D G3DSA:1.10.287.130 273 329 1.4E-15 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 BWK49_RS07575 cc915db3c0153e7cbdce724a0f6a69df 511 SUPERFAMILY SSF55874 334 501 5.63E-37 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS07575 cc915db3c0153e7cbdce724a0f6a69df 511 SMART SM00387 387 502 9.5E-38 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS07575 cc915db3c0153e7cbdce724a0f6a69df 511 SUPERFAMILY SSF47384 267 344 1.65E-17 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 BWK49_RS07575 cc915db3c0153e7cbdce724a0f6a69df 511 SMART SM00388 277 344 2.4E-22 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 BWK49_RS07575 cc915db3c0153e7cbdce724a0f6a69df 511 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 387 500 1.8E-22 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS07575 cc915db3c0153e7cbdce724a0f6a69df 511 SMART SM00304 207 269 4.7E-5 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 BWK49_RS07575 cc915db3c0153e7cbdce724a0f6a69df 511 PRINTS PR00344 Bacterial sensor protein C-terminal signature 486 499 1.1E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 BWK49_RS07575 cc915db3c0153e7cbdce724a0f6a69df 511 PRINTS PR00344 Bacterial sensor protein C-terminal signature 447 457 1.1E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 BWK49_RS07575 cc915db3c0153e7cbdce724a0f6a69df 511 PRINTS PR00344 Bacterial sensor protein C-terminal signature 463 481 1.1E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 BWK49_RS07575 cc915db3c0153e7cbdce724a0f6a69df 511 PRINTS PR00344 Bacterial sensor protein C-terminal signature 429 443 1.1E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 BWK49_RS07575 cc915db3c0153e7cbdce724a0f6a69df 511 Gene3D G3DSA:3.30.565.10 330 500 2.1E-40 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS19875 7d8719d9d26438ddc7e5cc6eb36af484 573 Gene3D G3DSA:1.10.3020.10 178 251 4.6E-8 T 06-07-2017 BWK49_RS19875 7d8719d9d26438ddc7e5cc6eb36af484 573 SMART SM00939 321 552 2.0E-51 T 06-07-2017 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 BWK49_RS19875 7d8719d9d26438ddc7e5cc6eb36af484 573 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 44 557 1.4E-84 T 06-07-2017 IPR005674 CocE/Serine esterase GO:0016787 BWK49_RS19875 7d8719d9d26438ddc7e5cc6eb36af484 573 Gene3D G3DSA:2.60.120.260 353 555 5.7E-54 T 06-07-2017 IPR008979 Galactose-binding domain-like BWK49_RS19875 7d8719d9d26438ddc7e5cc6eb36af484 573 SUPERFAMILY SSF49785 355 556 1.19E-47 T 06-07-2017 IPR008979 Galactose-binding domain-like BWK49_RS19875 7d8719d9d26438ddc7e5cc6eb36af484 573 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 335 535 9.0E-24 T 06-07-2017 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 BWK49_RS19875 7d8719d9d26438ddc7e5cc6eb36af484 573 Gene3D G3DSA:3.40.50.1820 32 175 1.1E-66 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS19875 7d8719d9d26438ddc7e5cc6eb36af484 573 Gene3D G3DSA:3.40.50.1820 252 352 1.1E-66 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS19875 7d8719d9d26438ddc7e5cc6eb36af484 573 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 48 307 1.3E-65 T 06-07-2017 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 BWK49_RS19875 7d8719d9d26438ddc7e5cc6eb36af484 573 SUPERFAMILY SSF53474 36 358 1.42E-40 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS13920 173e410d873fb1319c0ab63a153ab2b9 222 Gene3D G3DSA:3.90.226.10 3 187 2.6E-32 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS13920 173e410d873fb1319c0ab63a153ab2b9 222 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 212 1.7E-21 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 BWK49_RS13920 173e410d873fb1319c0ab63a153ab2b9 222 SUPERFAMILY SSF52096 3 212 1.14E-39 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS18220 6cd2d1a3b0c2ef5f849917b1edee4d6d 303 Pfam PF10128 Glucose-6-phosphate dehydrogenase subunit 52 294 6.1E-75 T 06-07-2017 IPR004555 Glucose-6-phosphate dehydrogenase assembly protein OpcA BWK49_RS18220 6cd2d1a3b0c2ef5f849917b1edee4d6d 303 TIGRFAM TIGR00534 OpcA: glucose-6-phosphate dehydrogenase assembly protein OpcA 2 302 4.7E-117 T 06-07-2017 IPR004555 Glucose-6-phosphate dehydrogenase assembly protein OpcA BWK49_RS24135 a551ad8266990d2d0f1ff6fb9691385c 267 Pfam PF00557 Metallopeptidase family M24 23 257 6.3E-41 T 06-07-2017 IPR000994 Peptidase M24, structural domain BWK49_RS24135 a551ad8266990d2d0f1ff6fb9691385c 267 PRINTS PR00599 Methionine aminopeptidase-1 signature 101 117 1.2E-21 T 06-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase BWK49_RS24135 a551ad8266990d2d0f1ff6fb9691385c 267 PRINTS PR00599 Methionine aminopeptidase-1 signature 208 220 1.2E-21 T 06-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase BWK49_RS24135 a551ad8266990d2d0f1ff6fb9691385c 267 PRINTS PR00599 Methionine aminopeptidase-1 signature 177 189 1.2E-21 T 06-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase BWK49_RS24135 a551ad8266990d2d0f1ff6fb9691385c 267 PRINTS PR00599 Methionine aminopeptidase-1 signature 78 91 1.2E-21 T 06-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase BWK49_RS24135 a551ad8266990d2d0f1ff6fb9691385c 267 Gene3D G3DSA:3.90.230.10 16 265 2.4E-78 T 06-07-2017 IPR000994 Peptidase M24, structural domain BWK49_RS24135 a551ad8266990d2d0f1ff6fb9691385c 267 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 17 265 2.1E-79 T 06-07-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 BWK49_RS24135 a551ad8266990d2d0f1ff6fb9691385c 267 SUPERFAMILY SSF55920 16 264 1.57E-73 T 06-07-2017 IPR000994 Peptidase M24, structural domain BWK49_RS24135 a551ad8266990d2d0f1ff6fb9691385c 267 Hamap MF_01974 Methionine aminopeptidase [map]. 13 266 36.789 T 06-07-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 BWK49_RS15965 6b234de56c463c490fe2d8e89e5969ae 73 SUPERFAMILY SSF160582 3 67 6.8E-28 T 06-07-2017 BWK49_RS15965 6b234de56c463c490fe2d8e89e5969ae 73 SMART SM00923 4 54 2.6E-32 T 06-07-2017 IPR005153 MbtH-like protein BWK49_RS15965 6b234de56c463c490fe2d8e89e5969ae 73 Gene3D G3DSA:3.90.820.10 11 67 2.6E-28 T 06-07-2017 BWK49_RS15965 6b234de56c463c490fe2d8e89e5969ae 73 Pfam PF03621 MbtH-like protein 4 54 1.8E-27 T 06-07-2017 IPR005153 MbtH-like protein BWK49_RS19380 5e8b153c2abd732a0249ce1be59fd3db 122 PIRSF PIRSF006910 1 122 2.0E-67 T 06-07-2017 IPR016499 Nucleic acid binding protein, Rv2694c, predicted BWK49_RS19380 5e8b153c2abd732a0249ce1be59fd3db 122 Gene3D G3DSA:2.40.50.140 40 121 9.2E-7 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS25055 89404bb4dadaac2bd472ed9a8968fa8e 135 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 10 111 3.0E-14 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain BWK49_RS25055 89404bb4dadaac2bd472ed9a8968fa8e 135 SUPERFAMILY SSF54593 8 117 1.88E-21 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS25055 89404bb4dadaac2bd472ed9a8968fa8e 135 Gene3D G3DSA:3.10.180.10 10 125 1.5E-23 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS14075 5b523ce1703355c38930c10edb394a64 263 SUPERFAMILY SSF51735 5 211 8.1E-36 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS14075 5b523ce1703355c38930c10edb394a64 263 Gene3D G3DSA:3.40.50.720 5 204 5.9E-29 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS14075 5b523ce1703355c38930c10edb394a64 263 Pfam PF13460 NAD(P)H-binding 9 132 4.0E-15 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS13600 27249314f173a1f9a6c333df0e7e37a9 111 Hamap MF_01483 RNA polymerase-binding protein RbpA [rbpA]. 16 111 22.438 T 06-07-2017 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 BWK49_RS13600 27249314f173a1f9a6c333df0e7e37a9 111 Pfam PF13397 RNA polymerase-binding protein 4 105 2.0E-39 T 06-07-2017 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 BWK49_RS03155 0b9ad597b49ed5b8a4ada5e1710f63b2 360 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 24 137 3.7E-25 T 06-07-2017 IPR003390 DNA integrity scanning protein, DisA, N-terminal BWK49_RS03155 0b9ad597b49ed5b8a4ada5e1710f63b2 360 Pfam PF12826 Helix-hairpin-helix motif 299 347 1.1E-6 T 06-07-2017 BWK49_RS03155 0b9ad597b49ed5b8a4ada5e1710f63b2 360 Gene3D G3DSA:1.10.150.20 297 347 1.1E-8 T 06-07-2017 BWK49_RS03155 0b9ad597b49ed5b8a4ada5e1710f63b2 360 Pfam PF10635 DisA bacterial checkpoint controller linker region 142 284 3.2E-47 T 06-07-2017 IPR018906 DNA integrity scanning, DisA, linker region BWK49_RS03155 0b9ad597b49ed5b8a4ada5e1710f63b2 360 Hamap MF_01438 DNA integrity scanning protein DisA [disA]. 4 357 42.844 T 06-07-2017 IPR023763 DNA integrity scanning protein, DisA BWK49_RS03155 0b9ad597b49ed5b8a4ada5e1710f63b2 360 Gene3D G3DSA:3.40.1700.10 18 140 3.5E-31 T 06-07-2017 BWK49_RS03155 0b9ad597b49ed5b8a4ada5e1710f63b2 360 SUPERFAMILY SSF143597 17 141 5.36E-28 T 06-07-2017 BWK49_RS03155 0b9ad597b49ed5b8a4ada5e1710f63b2 360 SUPERFAMILY SSF47781 283 350 1.27E-11 T 06-07-2017 IPR010994 RuvA domain 2-like BWK49_RS28310 242c1d7b5138fb20e1dc3a025cb62123 244 ProSitePatterns PS00893 Nudix box signature. 99 120 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 BWK49_RS28310 242c1d7b5138fb20e1dc3a025cb62123 244 Gene3D G3DSA:3.90.79.10 61 197 4.5E-29 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 BWK49_RS28310 242c1d7b5138fb20e1dc3a025cb62123 244 Pfam PF00293 NUDIX domain 82 187 1.9E-20 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 BWK49_RS28310 242c1d7b5138fb20e1dc3a025cb62123 244 SUPERFAMILY SSF55811 82 191 7.85E-31 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 BWK49_RS28310 242c1d7b5138fb20e1dc3a025cb62123 244 PRINTS PR00502 NUDIX hydrolase family signature 94 108 1.3E-7 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 BWK49_RS28310 242c1d7b5138fb20e1dc3a025cb62123 244 PRINTS PR00502 NUDIX hydrolase family signature 108 123 1.3E-7 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 BWK49_RS21260 0ff36aedd9aaf8c111dcbb5d6b661768 254 Gene3D G3DSA:3.90.226.10 14 233 3.2E-59 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS21260 0ff36aedd9aaf8c111dcbb5d6b661768 254 SUPERFAMILY SSF52096 15 241 3.78E-59 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS21260 0ff36aedd9aaf8c111dcbb5d6b661768 254 Pfam PF00378 Enoyl-CoA hydratase/isomerase 15 240 4.1E-47 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 BWK49_RS18770 260fa6688d13c0c56ac3a31afea23a1a 309 Gene3D G3DSA:2.40.100.10 141 306 2.0E-34 T 06-07-2017 IPR029000 Cyclophilin-like domain BWK49_RS18770 260fa6688d13c0c56ac3a31afea23a1a 309 SUPERFAMILY SSF50891 143 307 7.6E-35 T 06-07-2017 IPR029000 Cyclophilin-like domain BWK49_RS18770 260fa6688d13c0c56ac3a31afea23a1a 309 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 144 306 4.8E-25 T 06-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 BWK49_RS18770 260fa6688d13c0c56ac3a31afea23a1a 309 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 237 252 9.5E-7 T 06-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 BWK49_RS18770 260fa6688d13c0c56ac3a31afea23a1a 309 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 157 172 9.5E-7 T 06-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 BWK49_RS20760 ad9f750714f54b89d15d012b70657081 237 Pfam PF07510 Protein of unknown function (DUF1524) 90 205 2.7E-11 T 06-07-2017 IPR011089 Domain of unknown function DUF1524 BWK49_RS21625 ca98351a454ac5a15e5ff01a3c3530fe 132 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 11 120 6.6E-25 T 06-07-2017 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 BWK49_RS21625 ca98351a454ac5a15e5ff01a3c3530fe 132 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 9 126 18.834 T 06-07-2017 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 BWK49_RS07905 df1c78ffd7256306468c004786943cc9 81 SUPERFAMILY SSF143011 4 79 2.22E-15 T 06-07-2017 BWK49_RS07905 df1c78ffd7256306468c004786943cc9 81 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 29 80 3.1E-6 T 06-07-2017 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family BWK49_RS13415 6c01981a470d1043a14151a67635f249 291 Pfam PF00227 Proteasome subunit 56 240 7.6E-28 T 06-07-2017 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5687128|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-983168 BWK49_RS13415 6c01981a470d1043a14151a67635f249 291 Hamap MF_02113_B Proteasome subunit beta [prcB]. 5 288 45.581 T 06-07-2017 IPR022483 Peptidase T1A, proteasome beta-subunit, actinobacteria GO:0004298|GO:0005839|GO:0010498 BWK49_RS13415 6c01981a470d1043a14151a67635f249 291 TIGRFAM TIGR03690 20S_bact_beta: proteasome, beta subunit 54 279 2.5E-109 T 06-07-2017 IPR022483 Peptidase T1A, proteasome beta-subunit, actinobacteria GO:0004298|GO:0005839|GO:0010498 BWK49_RS13415 6c01981a470d1043a14151a67635f249 291 Gene3D G3DSA:3.60.20.10 58 272 3.2E-49 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal BWK49_RS13415 6c01981a470d1043a14151a67635f249 291 SUPERFAMILY SSF56235 23 273 1.12E-49 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal BWK49_RS01580 b0937fdfcac8031f6ac3ab65369cdd44 295 SUPERFAMILY SSF51735 3 159 9.38E-25 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS01580 b0937fdfcac8031f6ac3ab65369cdd44 295 SUPERFAMILY SSF48179 161 288 2.27E-14 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 BWK49_RS01580 b0937fdfcac8031f6ac3ab65369cdd44 295 PIRSF PIRSF000103 1 291 7.6E-47 T 06-07-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 BWK49_RS01580 b0937fdfcac8031f6ac3ab65369cdd44 295 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 161 274 2.8E-10 T 06-07-2017 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 BWK49_RS01580 b0937fdfcac8031f6ac3ab65369cdd44 295 Gene3D G3DSA:1.10.1040.10 161 286 5.4E-12 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 BWK49_RS01580 b0937fdfcac8031f6ac3ab65369cdd44 295 Gene3D G3DSA:3.40.50.720 3 158 4.2E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS01580 b0937fdfcac8031f6ac3ab65369cdd44 295 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 3 157 7.4E-23 T 06-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 BWK49_RS25630 f5bd87ef10fb5d45f64054c42dbc093e 163 SUPERFAMILY SSF51182 15 152 1.05E-27 T 06-07-2017 IPR011051 RmlC-like cupin domain BWK49_RS25630 f5bd87ef10fb5d45f64054c42dbc093e 163 Pfam PF07883 Cupin domain 58 127 5.8E-18 T 06-07-2017 IPR013096 Cupin 2, conserved barrel BWK49_RS25630 f5bd87ef10fb5d45f64054c42dbc093e 163 Gene3D G3DSA:2.60.120.10 31 150 7.4E-28 T 06-07-2017 IPR014710 RmlC-like jelly roll fold BWK49_RS21165 09ac204570fe7df03db159bc0a07e048 334 SUPERFAMILY SSF50022 51 151 4.71E-16 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS21165 09ac204570fe7df03db159bc0a07e048 334 Pfam PF00355 Rieske [2Fe-2S] domain 56 127 6.3E-9 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS21165 09ac204570fe7df03db159bc0a07e048 334 Gene3D G3DSA:2.102.10.10 56 127 3.2E-12 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS04770 81357af76143fc466437ff5931ed5918 485 SUPERFAMILY SSF51905 7 258 1.14E-58 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS04770 81357af76143fc466437ff5931ed5918 485 Pfam PF00743 Flavin-binding monooxygenase-like 10 340 1.7E-18 T 06-07-2017 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 BWK49_RS04770 81357af76143fc466437ff5931ed5918 485 SUPERFAMILY SSF51905 279 454 1.5E-19 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS04770 81357af76143fc466437ff5931ed5918 485 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 169 193 2.1E-5 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 BWK49_RS04770 81357af76143fc466437ff5931ed5918 485 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 130 138 2.1E-5 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 BWK49_RS04770 81357af76143fc466437ff5931ed5918 485 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 10 32 2.1E-5 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 BWK49_RS04770 81357af76143fc466437ff5931ed5918 485 Gene3D G3DSA:3.50.50.60 3 214 2.6E-64 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS04770 81357af76143fc466437ff5931ed5918 485 Gene3D G3DSA:3.50.50.60 293 472 1.2E-14 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS08920 91bf5efc6fd9c751bacdbc0ab57c1a36 296 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 61 288 2.1E-44 T 06-07-2017 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 BWK49_RS08920 91bf5efc6fd9c751bacdbc0ab57c1a36 296 Pfam PF05175 Methyltransferase small domain 111 202 2.6E-10 T 06-07-2017 IPR007848 Methyltransferase small domain GO:0008168 BWK49_RS08920 91bf5efc6fd9c751bacdbc0ab57c1a36 296 Gene3D G3DSA:3.40.50.150 93 287 1.4E-53 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS08920 91bf5efc6fd9c751bacdbc0ab57c1a36 296 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 192 198 - T 06-07-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 BWK49_RS08920 91bf5efc6fd9c751bacdbc0ab57c1a36 296 SUPERFAMILY SSF53335 11 284 1.48E-43 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS08920 91bf5efc6fd9c751bacdbc0ab57c1a36 296 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 32 283 2.4E-63 T 06-07-2017 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 BWK49_RS08920 91bf5efc6fd9c751bacdbc0ab57c1a36 296 Gene3D G3DSA:1.10.8.10 9 91 6.7E-14 T 06-07-2017 BWK49_RS08920 91bf5efc6fd9c751bacdbc0ab57c1a36 296 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 10 287 39.736 T 06-07-2017 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 BWK49_RS10595 125000945a73ccf961fa2767ace5c82c 114 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 22 113 2.1E-24 T 06-07-2017 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS14090 11bd96b129d1bc1bd3c1585d56276c9c 235 Pfam PF05988 Bacterial protein of unknown function (DUF899) 8 208 1.8E-58 T 06-07-2017 IPR010296 Protein of unknown function DUF899, thioredoxin-like BWK49_RS11755 e09dbdf6a4fe8b7b1e9c518c006e0b10 657 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 159 178 4.0E-5 T 06-07-2017 BWK49_RS11755 e09dbdf6a4fe8b7b1e9c518c006e0b10 657 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 327 345 4.0E-5 T 06-07-2017 BWK49_RS11755 e09dbdf6a4fe8b7b1e9c518c006e0b10 657 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 160 372 6.5E-19 T 06-07-2017 BWK49_RS11755 e09dbdf6a4fe8b7b1e9c518c006e0b10 657 SUPERFAMILY SSF51905 158 383 1.4E-50 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS11755 e09dbdf6a4fe8b7b1e9c518c006e0b10 657 SUPERFAMILY SSF51905 462 562 1.4E-50 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS11755 e09dbdf6a4fe8b7b1e9c518c006e0b10 657 Gene3D G3DSA:3.50.50.60 151 363 1.1E-53 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS11755 e09dbdf6a4fe8b7b1e9c518c006e0b10 657 Gene3D G3DSA:3.50.50.60 423 653 2.9E-9 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS11755 e09dbdf6a4fe8b7b1e9c518c006e0b10 657 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 327 352 2.7E-6 T 06-07-2017 BWK49_RS11755 e09dbdf6a4fe8b7b1e9c518c006e0b10 657 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 158 180 2.7E-6 T 06-07-2017 BWK49_RS22415 18e3d23db3ad34666cb7351a5e1f6319 162 PIRSF PIRSF000303 2 162 1.0E-57 T 06-07-2017 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 BWK49_RS22415 18e3d23db3ad34666cb7351a5e1f6319 162 Pfam PF00255 Glutathione peroxidase 5 109 1.4E-35 T 06-07-2017 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 BWK49_RS22415 18e3d23db3ad34666cb7351a5e1f6319 162 Gene3D G3DSA:3.40.30.10 3 160 2.0E-57 T 06-07-2017 IPR012336 Thioredoxin-like fold BWK49_RS22415 18e3d23db3ad34666cb7351a5e1f6319 162 SUPERFAMILY SSF52833 3 160 2.21E-51 T 06-07-2017 IPR012336 Thioredoxin-like fold BWK49_RS22415 18e3d23db3ad34666cb7351a5e1f6319 162 PRINTS PR01011 Glutathione peroxidase family signature 21 38 1.4E-14 T 06-07-2017 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 BWK49_RS22415 18e3d23db3ad34666cb7351a5e1f6319 162 PRINTS PR01011 Glutathione peroxidase family signature 122 131 1.4E-14 T 06-07-2017 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 BWK49_RS22415 18e3d23db3ad34666cb7351a5e1f6319 162 PRINTS PR01011 Glutathione peroxidase family signature 56 72 1.4E-14 T 06-07-2017 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 BWK49_RS26340 a56b3864fee3f7412fb127041c5577ea 461 PRINTS PR01217 Proline rich extensin signature 347 368 8.1E-11 T 06-07-2017 BWK49_RS26340 a56b3864fee3f7412fb127041c5577ea 461 PRINTS PR01217 Proline rich extensin signature 397 422 8.1E-11 T 06-07-2017 BWK49_RS26340 a56b3864fee3f7412fb127041c5577ea 461 PRINTS PR01217 Proline rich extensin signature 368 384 8.1E-11 T 06-07-2017 BWK49_RS26340 a56b3864fee3f7412fb127041c5577ea 461 PRINTS PR01217 Proline rich extensin signature 333 345 8.1E-11 T 06-07-2017 BWK49_RS13770 5ff5e5509548510aed039a1ea9f6022e 287 Gene3D G3DSA:1.10.3720.10 49 278 3.2E-64 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS13770 5ff5e5509548510aed039a1ea9f6022e 287 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 72 270 6.6E-16 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS13770 5ff5e5509548510aed039a1ea9f6022e 287 SUPERFAMILY SSF161098 40 269 2.22E-62 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS17265 d3d05683879511cdacad86c031ca3582 271 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 19 263 32.449 T 06-07-2017 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 BWK49_RS17265 d3d05683879511cdacad86c031ca3582 271 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 15 247 8.0E-61 T 06-07-2017 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 BWK49_RS17265 d3d05683879511cdacad86c031ca3582 271 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 55 68 - T 06-07-2017 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 BWK49_RS17265 d3d05683879511cdacad86c031ca3582 271 Pfam PF00290 Tryptophan synthase alpha chain 16 247 4.0E-67 T 06-07-2017 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 BWK49_RS17265 d3d05683879511cdacad86c031ca3582 271 SUPERFAMILY SSF51366 9 259 1.88E-77 T 06-07-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 BWK49_RS17265 d3d05683879511cdacad86c031ca3582 271 Gene3D G3DSA:3.20.20.70 10 266 6.8E-89 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 BWK49_RS25980 013bf3770c919cfeaac3a1a0f1ac4be1 464 Gene3D G3DSA:3.50.50.60 3 111 3.9E-20 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS25980 013bf3770c919cfeaac3a1a0f1ac4be1 464 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 333 3.3E-51 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS25980 013bf3770c919cfeaac3a1a0f1ac4be1 464 SUPERFAMILY SSF51905 2 342 3.38E-29 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS25980 013bf3770c919cfeaac3a1a0f1ac4be1 464 Gene3D G3DSA:3.50.50.60 112 341 7.9E-23 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS25980 013bf3770c919cfeaac3a1a0f1ac4be1 464 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 296 318 4.9E-12 T 06-07-2017 BWK49_RS25980 013bf3770c919cfeaac3a1a0f1ac4be1 464 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 4.9E-12 T 06-07-2017 BWK49_RS25980 013bf3770c919cfeaac3a1a0f1ac4be1 464 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 105 123 4.9E-12 T 06-07-2017 BWK49_RS25980 013bf3770c919cfeaac3a1a0f1ac4be1 464 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 165 183 4.9E-12 T 06-07-2017 BWK49_RS25980 013bf3770c919cfeaac3a1a0f1ac4be1 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 165 190 1.0E-7 T 06-07-2017 BWK49_RS25980 013bf3770c919cfeaac3a1a0f1ac4be1 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 1.0E-7 T 06-07-2017 BWK49_RS25980 013bf3770c919cfeaac3a1a0f1ac4be1 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 311 318 1.0E-7 T 06-07-2017 BWK49_RS08430 be672c209765382b3b7f234f35833bc3 317 Hamap MF_02122 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [dapD]. 4 315 44.174 T 06-07-2017 IPR026586 Type 2 tetrahydrodipicolinate N-succinyltransferase family GO:0008666 KEGG: 00300+2.3.1.117 BWK49_RS08430 be672c209765382b3b7f234f35833bc3 317 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 232 264 1.4E-15 T 06-07-2017 IPR001451 Hexapeptide repeat BWK49_RS08430 be672c209765382b3b7f234f35833bc3 317 Gene3D G3DSA:2.160.10.10 152 291 2.6E-31 T 06-07-2017 BWK49_RS08430 be672c209765382b3b7f234f35833bc3 317 Gene3D G3DSA:3.30.60.70 111 150 8.2E-6 T 06-07-2017 IPR032784 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, middle domain KEGG: 00300+2.3.1.117 BWK49_RS08430 be672c209765382b3b7f234f35833bc3 317 SUPERFAMILY SSF51161 71 297 4.16E-39 T 06-07-2017 IPR011004 Trimeric LpxA-like BWK49_RS08430 be672c209765382b3b7f234f35833bc3 317 TIGRFAM TIGR03535 DapD_actino: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase 6 317 9.3E-159 T 06-07-2017 IPR019875 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, actinobacteria KEGG: 00300+2.3.1.117 BWK49_RS08430 be672c209765382b3b7f234f35833bc3 317 Pfam PF14789 Tetrahydrodipicolinate N-succinyltransferase middle 111 150 5.6E-20 T 06-07-2017 IPR032784 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, middle domain KEGG: 00300+2.3.1.117 BWK49_RS00860 d92558abd886affd5c5b9c6115780dc5 95 Gene3D G3DSA:1.10.287.1060 5 95 2.3E-9 T 06-07-2017 BWK49_RS00860 d92558abd886affd5c5b9c6115780dc5 95 ProDom PD065399 ESAT-6-LIKE ESAT-6 ORF3890C LIKE 1 95 1.0E-48 T 06-07-2017 IPR020167 ESAT-6-like protein 11, putative BWK49_RS00860 d92558abd886affd5c5b9c6115780dc5 95 SUPERFAMILY SSF140453 3 95 1.57E-17 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like BWK49_RS00860 d92558abd886affd5c5b9c6115780dc5 95 Pfam PF06013 Proteins of 100 residues with WXG 5 88 1.9E-8 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like BWK49_RS20335 c227dae2cfe149a824096584c66606ef 521 SMART SM00382 99 307 7.7E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS20335 c227dae2cfe149a824096584c66606ef 521 Gene3D G3DSA:3.40.50.300 95 303 2.9E-75 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS20335 c227dae2cfe149a824096584c66606ef 521 Pfam PF00448 SRP54-type protein, GTPase domain 100 302 5.2E-69 T 06-07-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 BWK49_RS20335 c227dae2cfe149a824096584c66606ef 521 SUPERFAMILY SSF52540 42 360 8.86E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS20335 c227dae2cfe149a824096584c66606ef 521 TIGRFAM TIGR00959 ffh: signal recognition particle protein 2 432 7.6E-178 T 06-07-2017 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 BWK49_RS20335 c227dae2cfe149a824096584c66606ef 521 Pfam PF02881 SRP54-type protein, helical bundle domain 5 82 3.7E-20 T 06-07-2017 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 BWK49_RS20335 c227dae2cfe149a824096584c66606ef 521 SMART SM00962 100 302 6.5E-110 T 06-07-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 BWK49_RS20335 c227dae2cfe149a824096584c66606ef 521 Pfam PF02978 Signal peptide binding domain 334 431 2.3E-29 T 06-07-2017 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 BWK49_RS20335 c227dae2cfe149a824096584c66606ef 521 Gene3D G3DSA:1.20.120.140 2 89 4.6E-32 T 06-07-2017 BWK49_RS20335 c227dae2cfe149a824096584c66606ef 521 SUPERFAMILY SSF47446 304 434 2.62E-42 T 06-07-2017 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 BWK49_RS20335 c227dae2cfe149a824096584c66606ef 521 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 275 288 - T 06-07-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 BWK49_RS20335 c227dae2cfe149a824096584c66606ef 521 SMART SM00963 1 86 3.6E-33 T 06-07-2017 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 BWK49_RS20335 c227dae2cfe149a824096584c66606ef 521 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 5 444 33.524 T 06-07-2017 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 BWK49_RS20335 c227dae2cfe149a824096584c66606ef 521 Gene3D G3DSA:1.10.260.30 334 434 8.7E-36 T 06-07-2017 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 BWK49_RS08780 477a5235f50e8abfdedcd804ecd6a6d1 611 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 232 318 1.5E-19 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 BWK49_RS08780 477a5235f50e8abfdedcd804ecd6a6d1 611 Gene3D G3DSA:3.40.50.300 3 256 2.4E-68 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS08780 477a5235f50e8abfdedcd804ecd6a6d1 611 Gene3D G3DSA:3.40.50.300 349 600 1.7E-77 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS08780 477a5235f50e8abfdedcd804ecd6a6d1 611 SMART SM00382 385 576 9.4E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS08780 477a5235f50e8abfdedcd804ecd6a6d1 611 SMART SM00382 33 232 1.7E-16 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS08780 477a5235f50e8abfdedcd804ecd6a6d1 611 SUPERFAMILY SSF52540 4 252 1.7E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS08780 477a5235f50e8abfdedcd804ecd6a6d1 611 ProSitePatterns PS00211 ABC transporters family signature. 499 513 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 BWK49_RS08780 477a5235f50e8abfdedcd804ecd6a6d1 611 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 578 610 8.8E-8 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 BWK49_RS08780 477a5235f50e8abfdedcd804ecd6a6d1 611 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 234 299 7.1E-16 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 BWK49_RS08780 477a5235f50e8abfdedcd804ecd6a6d1 611 SUPERFAMILY SSF52540 350 598 1.78E-69 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS08780 477a5235f50e8abfdedcd804ecd6a6d1 611 Pfam PF00005 ABC transporter 377 526 4.0E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 BWK49_RS08780 477a5235f50e8abfdedcd804ecd6a6d1 611 Pfam PF00005 ABC transporter 25 182 1.0E-24 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 BWK49_RS08780 477a5235f50e8abfdedcd804ecd6a6d1 611 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 BWK49_RS15520 858c7924bddc11f87eb6c03dcdd11f80 456 SMART SM00507 352 404 0.0045 T 06-07-2017 IPR003615 HNH nuclease BWK49_RS15520 858c7924bddc11f87eb6c03dcdd11f80 456 Pfam PF02720 Domain of unknown function (DUF222) 38 361 3.0E-95 T 06-07-2017 IPR003870 Domain of unknown function DUF222 BWK49_RS15520 858c7924bddc11f87eb6c03dcdd11f80 456 ProDom PD008243 RV1792C/MT1741/MB1728C RV1945/MT1995 MB1980 MB0098C RV3466/MT3572 VERY RV1128C/MT1160 RV1148C/MT1183 MB1159C RV0095C 8 92 2.0E-19 T 06-07-2017 BWK49_RS24765 34dded9b3b9c91b5b37030d1d739d904 388 SUPERFAMILY SSF51905 262 371 1.38E-52 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS24765 34dded9b3b9c91b5b37030d1d739d904 388 SUPERFAMILY SSF51905 1 167 1.38E-52 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS24765 34dded9b3b9c91b5b37030d1d739d904 388 Pfam PF01494 FAD binding domain 3 332 3.0E-16 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 BWK49_RS24765 34dded9b3b9c91b5b37030d1d739d904 388 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 290 306 3.9E-13 T 06-07-2017 BWK49_RS24765 34dded9b3b9c91b5b37030d1d739d904 388 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 3.9E-13 T 06-07-2017 BWK49_RS24765 34dded9b3b9c91b5b37030d1d739d904 388 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 146 161 3.9E-13 T 06-07-2017 BWK49_RS24765 34dded9b3b9c91b5b37030d1d739d904 388 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 275 290 3.9E-13 T 06-07-2017 BWK49_RS24765 34dded9b3b9c91b5b37030d1d739d904 388 Gene3D G3DSA:3.50.50.60 263 338 1.3E-31 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS24765 34dded9b3b9c91b5b37030d1d739d904 388 Gene3D G3DSA:3.50.50.60 1 173 1.3E-31 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS04395 b86f5c191cd389db6a0bb046f3a8d021 108 Pfam PF00934 PE family 12 100 3.9E-11 T 06-07-2017 IPR000084 PE-PGRS family, N-terminal BWK49_RS20665 fc7ba42ea39eb8ed600a79160351f2b2 307 SUPERFAMILY SSF160240 220 289 1.31E-8 T 06-07-2017 BWK49_RS20665 fc7ba42ea39eb8ed600a79160351f2b2 307 Pfam PF01545 Cation efflux family 24 212 9.4E-39 T 06-07-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 BWK49_RS20665 fc7ba42ea39eb8ed600a79160351f2b2 307 SUPERFAMILY SSF161111 16 213 1.22E-45 T 06-07-2017 BWK49_RS20665 fc7ba42ea39eb8ed600a79160351f2b2 307 Gene3D G3DSA:1.20.1510.10 18 212 1.2E-46 T 06-07-2017 IPR027469 Cation efflux protein transmembrane domain BWK49_RS20665 fc7ba42ea39eb8ed600a79160351f2b2 307 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 18 292 6.6E-73 T 06-07-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 BWK49_RS22005 5f1ae1ca9fcbd742cd3eb6a1551c6167 441 Gene3D G3DSA:1.10.645.10 369 434 4.5E-67 T 06-07-2017 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS22005 5f1ae1ca9fcbd742cd3eb6a1551c6167 441 Gene3D G3DSA:1.10.645.10 35 325 4.5E-67 T 06-07-2017 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS22005 5f1ae1ca9fcbd742cd3eb6a1551c6167 441 SUPERFAMILY SSF56762 49 441 2.09E-118 T 06-07-2017 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS22005 5f1ae1ca9fcbd742cd3eb6a1551c6167 441 TIGRFAM TIGR01962 NuoD: NADH dehydrogenase (quinone), D subunit 39 441 1.9E-180 T 06-07-2017 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS22005 5f1ae1ca9fcbd742cd3eb6a1551c6167 441 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 31 441 46.176 T 06-07-2017 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS22005 5f1ae1ca9fcbd742cd3eb6a1551c6167 441 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 76 87 - T 06-07-2017 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS22005 5f1ae1ca9fcbd742cd3eb6a1551c6167 441 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 156 441 2.0E-109 T 06-07-2017 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS28730 d90410b7b903f7dc9f08f0bc1ffd1ad5 325 Pfam PF12083 Domain of unknown function (DUF3560) 89 209 2.7E-31 T 06-07-2017 IPR021944 Protein of unknown function DUF3560 BWK49_RS11135 4afcd7ff2e16738248dc12d791bd0295 138 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 21 123 4.2E-12 T 06-07-2017 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-75105 BWK49_RS11135 4afcd7ff2e16738248dc12d791bd0295 138 SUPERFAMILY SSF54637 12 125 3.3E-23 T 06-07-2017 IPR029069 HotDog domain BWK49_RS11135 4afcd7ff2e16738248dc12d791bd0295 138 Pfam PF03061 Thioesterase superfamily 40 112 1.6E-12 T 06-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 BWK49_RS11135 4afcd7ff2e16738248dc12d791bd0295 138 Gene3D G3DSA:3.10.129.10 21 126 1.2E-24 T 06-07-2017 IPR029069 HotDog domain BWK49_RS07020 8809d2ba16a9d1ca161eee5c047c8029 464 Gene3D G3DSA:3.40.50.300 55 250 8.0E-27 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS07020 8809d2ba16a9d1ca161eee5c047c8029 464 SUPERFAMILY SSF52540 53 97 5.87E-26 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS07020 8809d2ba16a9d1ca161eee5c047c8029 464 SUPERFAMILY SSF52540 142 340 5.87E-26 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS07020 8809d2ba16a9d1ca161eee5c047c8029 464 Pfam PF00158 Sigma-54 interaction domain 175 232 3.7E-5 T 06-07-2017 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 BWK49_RS15535 3d8efc68447b623a19f783291233df9b 419 Gene3D G3DSA:3.90.1200.10 160 355 1.5E-4 T 06-07-2017 BWK49_RS15535 3d8efc68447b623a19f783291233df9b 419 SUPERFAMILY SSF56112 216 362 1.73E-11 T 06-07-2017 IPR011009 Protein kinase-like domain BWK49_RS15535 3d8efc68447b623a19f783291233df9b 419 SUPERFAMILY SSF56112 36 188 1.73E-11 T 06-07-2017 IPR011009 Protein kinase-like domain BWK49_RS21975 12a741467e22ce5fb7db39becd5b2fbe 137 SUPERFAMILY SSF54427 7 135 1.43E-16 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS21975 12a741467e22ce5fb7db39becd5b2fbe 137 Pfam PF12680 SnoaL-like domain 14 122 3.5E-8 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain BWK49_RS21975 12a741467e22ce5fb7db39becd5b2fbe 137 Gene3D G3DSA:3.10.450.50 3 133 1.4E-12 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS15195 6e7bb962e474230a3653128369147392 467 Pfam PF00823 PPE family 5 161 4.0E-60 T 06-07-2017 IPR000030 PPE family BWK49_RS15195 6e7bb962e474230a3653128369147392 467 SUPERFAMILY SSF140459 3 174 1.1E-59 T 06-07-2017 BWK49_RS15195 6e7bb962e474230a3653128369147392 467 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 314 395 3.3E-12 T 06-07-2017 IPR022171 PPE family, C-terminal BWK49_RS28460 4d997912fe2b7ee1dedbfb7a8ea9a4fc 199 SUPERFAMILY SSF53098 62 159 4.93E-19 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS28460 4d997912fe2b7ee1dedbfb7a8ea9a4fc 199 Gene3D G3DSA:3.30.420.10 3 153 1.8E-18 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS28460 4d997912fe2b7ee1dedbfb7a8ea9a4fc 199 Pfam PF13683 Integrase core domain 89 153 1.7E-13 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 BWK49_RS16680 6250e37ee711811e4ba981fd07d5c5be 211 SUPERFAMILY SSF48452 34 195 8.72E-8 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 BWK49_RS16680 6250e37ee711811e4ba981fd07d5c5be 211 Gene3D G3DSA:1.25.40.10 22 195 1.8E-8 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 BWK49_RS25575 60d763bd886d8a89830189ff016026b4 580 Gene3D G3DSA:3.40.30.10 280 431 2.8E-47 T 06-07-2017 IPR012336 Thioredoxin-like fold BWK49_RS25575 60d763bd886d8a89830189ff016026b4 580 SUPERFAMILY SSF52833 298 428 4.45E-32 T 06-07-2017 IPR012336 Thioredoxin-like fold BWK49_RS25575 60d763bd886d8a89830189ff016026b4 580 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 9 213 4.9E-24 T 06-07-2017 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 BWK49_RS25575 60d763bd886d8a89830189ff016026b4 580 Pfam PF00578 AhpC/TSA family 298 409 9.2E-12 T 06-07-2017 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 BWK49_RS25575 60d763bd886d8a89830189ff016026b4 580 Gene3D G3DSA:2.60.120.260 452 579 1.1E-43 T 06-07-2017 IPR008979 Galactose-binding domain-like BWK49_RS09630 8698902c9128594ea3e7c590ca56d927 146 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 29 143 6.6E-36 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 BWK49_RS09630 8698902c9128594ea3e7c590ca56d927 146 Pfam PF04075 Domain of unknown function (DUF385) 13 144 2.1E-46 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 BWK49_RS09630 8698902c9128594ea3e7c590ca56d927 146 Gene3D G3DSA:2.30.110.10 39 144 2.3E-5 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 BWK49_RS23105 392de01c1eb3fdb0e3c998a8c245ec84 341 SUPERFAMILY SSF161098 39 322 7.19E-26 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS23105 392de01c1eb3fdb0e3c998a8c245ec84 341 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 105 329 7.3E-13 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS23105 392de01c1eb3fdb0e3c998a8c245ec84 341 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 18 330 2.9E-95 T 06-07-2017 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 BWK49_RS23105 392de01c1eb3fdb0e3c998a8c245ec84 341 Gene3D G3DSA:1.10.3720.10 32 330 2.7E-30 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS20320 366a40fe23ba6676f62d4f3f1222724e 197 Gene3D G3DSA:1.10.357.10 1 194 7.4E-21 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS20320 366a40fe23ba6676f62d4f3f1222724e 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 61 5.9E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS20320 366a40fe23ba6676f62d4f3f1222724e 197 ProSitePatterns PS01081 TetR-type HTH domain signature. 28 59 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site BWK49_RS20320 366a40fe23ba6676f62d4f3f1222724e 197 SUPERFAMILY SSF46689 2 81 1.59E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS15045 a1c7ad0f9f677e3247e10ccc52159d60 731 Gene3D G3DSA:1.20.1220.12 594 728 5.8E-71 T 06-07-2017 BWK49_RS15045 a1c7ad0f9f677e3247e10ccc52159d60 731 SUPERFAMILY SSF51645 2 726 1.16E-298 T 06-07-2017 IPR011076 Malate synthase-like GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 BWK49_RS15045 a1c7ad0f9f677e3247e10ccc52159d60 731 Pfam PF01274 Malate synthase 17 701 8.7E-200 T 06-07-2017 IPR001465 Malate synthase GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 BWK49_RS15045 a1c7ad0f9f677e3247e10ccc52159d60 731 Gene3D G3DSA:2.170.170.11 298 336 9.8E-66 T 06-07-2017 IPR023310 Malate synthase G, beta sub-domain GO:0004474 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 BWK49_RS15045 a1c7ad0f9f677e3247e10ccc52159d60 731 Gene3D G3DSA:2.170.170.11 136 264 9.8E-66 T 06-07-2017 IPR023310 Malate synthase G, beta sub-domain GO:0004474 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 BWK49_RS15045 a1c7ad0f9f677e3247e10ccc52159d60 731 Gene3D G3DSA:1.10.1860.10 1 88 4.4E-35 T 06-07-2017 BWK49_RS15045 a1c7ad0f9f677e3247e10ccc52159d60 731 TIGRFAM TIGR01345 malate_syn_G: malate synthase G 4 726 0.0 T 06-07-2017 IPR006253 Malate synthase G GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 BWK49_RS15045 a1c7ad0f9f677e3247e10ccc52159d60 731 Gene3D G3DSA:3.20.20.360 266 296 2.1E-146 T 06-07-2017 BWK49_RS15045 a1c7ad0f9f677e3247e10ccc52159d60 731 Gene3D G3DSA:3.20.20.360 89 135 2.1E-146 T 06-07-2017 BWK49_RS15045 a1c7ad0f9f677e3247e10ccc52159d60 731 Gene3D G3DSA:3.20.20.360 337 591 2.1E-146 T 06-07-2017 BWK49_RS15045 a1c7ad0f9f677e3247e10ccc52159d60 731 Hamap MF_00641 Malate synthase G [glcB]. 1 731 405.214 T 06-07-2017 IPR006253 Malate synthase G GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 BWK49_RS21250 af994ea7280feff2fd726d0b05f27d0d 346 Gene3D G3DSA:3.40.50.150 38 109 1.7E-6 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS21250 af994ea7280feff2fd726d0b05f27d0d 346 SUPERFAMILY SSF53335 35 119 4.28E-9 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS16195 98bfa70b7b7805fb4d75c3f313e38a78 98 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 5 93 2.8E-19 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like BWK49_RS16195 98bfa70b7b7805fb4d75c3f313e38a78 98 SUPERFAMILY SSF140453 4 97 1.16E-19 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like BWK49_RS16195 98bfa70b7b7805fb4d75c3f313e38a78 98 Pfam PF06013 Proteins of 100 residues with WXG 5 90 9.5E-19 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like BWK49_RS16195 98bfa70b7b7805fb4d75c3f313e38a78 98 Gene3D G3DSA:1.10.287.1060 1 97 6.5E-12 T 06-07-2017 BWK49_RS06210 cd6cc385a33a8f506c8143de4ee3ef7d 137 SUPERFAMILY SSF50022 23 136 8.51E-26 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS06210 cd6cc385a33a8f506c8143de4ee3ef7d 137 Pfam PF00355 Rieske [2Fe-2S] domain 24 118 8.1E-11 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS06210 cd6cc385a33a8f506c8143de4ee3ef7d 137 Gene3D G3DSA:2.102.10.10 23 136 1.4E-29 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS08230 eea2430bf6f298abc1cb9b8da90addd0 432 Pfam PF09594 Protein of unknown function (DUF2029) 101 333 1.2E-52 T 06-07-2017 IPR018584 Glycosyltransferase family 87 GO:0016758 BWK49_RS21460 5a69d4c8924bf2abce3df779c7558fbd 223 Pfam PF09203 MspA 50 221 7.1E-42 T 06-07-2017 IPR015286 Porin family, mycobacterial-type BWK49_RS21460 5a69d4c8924bf2abce3df779c7558fbd 223 Gene3D G3DSA:2.60.40.1650 40 107 2.1E-46 T 06-07-2017 BWK49_RS21460 5a69d4c8924bf2abce3df779c7558fbd 223 Gene3D G3DSA:2.60.40.1650 161 221 2.1E-46 T 06-07-2017 BWK49_RS21460 5a69d4c8924bf2abce3df779c7558fbd 223 SUPERFAMILY SSF56959 39 222 2.68E-60 T 06-07-2017 IPR016183 Leukocidin/porin GO:0005576|GO:0051715 BWK49_RS06025 0ed3474bed33c5fcb1c6e102353e1c01 269 Gene3D G3DSA:3.40.50.720 9 248 4.1E-75 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS06025 0ed3474bed33c5fcb1c6e102353e1c01 269 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 22 248 5.2E-59 T 06-07-2017 BWK49_RS06025 0ed3474bed33c5fcb1c6e102353e1c01 269 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 1.2E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS06025 0ed3474bed33c5fcb1c6e102353e1c01 269 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 1.2E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS06025 0ed3474bed33c5fcb1c6e102353e1c01 269 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 1.2E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS06025 0ed3474bed33c5fcb1c6e102353e1c01 269 SUPERFAMILY SSF51735 12 248 5.53E-74 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS06025 0ed3474bed33c5fcb1c6e102353e1c01 269 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS06025 0ed3474bed33c5fcb1c6e102353e1c01 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 2.1E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS06025 0ed3474bed33c5fcb1c6e102353e1c01 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 2.1E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS06025 0ed3474bed33c5fcb1c6e102353e1c01 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 2.1E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS06025 0ed3474bed33c5fcb1c6e102353e1c01 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 2.1E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS06025 0ed3474bed33c5fcb1c6e102353e1c01 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 2.1E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS06025 0ed3474bed33c5fcb1c6e102353e1c01 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 2.1E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS28370 221ab2cc6e66e4d37d0272473d93be4d 187 Gene3D G3DSA:3.30.300.120 41 118 1.8E-23 T 06-07-2017 BWK49_RS28370 221ab2cc6e66e4d37d0272473d93be4d 187 SUPERFAMILY SSF82708 133 185 7.46E-10 T 06-07-2017 IPR001374 R3H domain GO:0003676 BWK49_RS28370 221ab2cc6e66e4d37d0272473d93be4d 187 SMART SM00393 108 187 8.1E-24 T 06-07-2017 IPR001374 R3H domain GO:0003676 BWK49_RS28370 221ab2cc6e66e4d37d0272473d93be4d 187 Gene3D G3DSA:3.30.1370.50 120 185 3.4E-24 T 06-07-2017 IPR001374 R3H domain GO:0003676 BWK49_RS28370 221ab2cc6e66e4d37d0272473d93be4d 187 Pfam PF01424 R3H domain 127 184 1.8E-14 T 06-07-2017 IPR001374 R3H domain GO:0003676 BWK49_RS09120 b2a1c6d0bbdc21c7011217b79bee752d 223 SUPERFAMILY SSF144091 27 207 4.84E-30 T 06-07-2017 BWK49_RS09120 b2a1c6d0bbdc21c7011217b79bee752d 223 Pfam PF01694 Rhomboid family 59 203 3.8E-25 T 06-07-2017 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 BWK49_RS09120 b2a1c6d0bbdc21c7011217b79bee752d 223 Gene3D G3DSA:1.20.1540.10 19 201 4.5E-17 T 06-07-2017 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 BWK49_RS05420 553ac6630128efafc4a4f3f040f20d8f 829 Gene3D G3DSA:1.10.443.10 465 654 7.5E-22 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 BWK49_RS05420 553ac6630128efafc4a4f3f040f20d8f 829 SUPERFAMILY SSF56349 333 654 1.0E-23 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 BWK49_RS05420 553ac6630128efafc4a4f3f040f20d8f 829 Pfam PF00589 Phage integrase family 466 644 1.2E-11 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 BWK49_RS06475 df75a843a2bdcb764c22a21f0f408872 359 Gene3D G3DSA:3.40.50.10540 4 302 3.6E-94 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS06475 df75a843a2bdcb764c22a21f0f408872 359 Pfam PF02515 CoA-transferase family III 6 349 7.1E-77 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 BWK49_RS06475 df75a843a2bdcb764c22a21f0f408872 359 SUPERFAMILY SSF89796 4 350 6.67E-101 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS28840 95d0fcfb7ce8243623a7d7a5eeba1f61 115 Pfam PF10824 Excreted virulence factor EspC, type VII ESX diderm 25 114 7.4E-8 T 06-07-2017 IPR022536 ESX-1 secretion-associated protein EspC BWK49_RS03200 51e0d8b86ef795f9a2bc0dc985e5e88a 413 PRINTS PR00758 Arsenical pump membrane protein signature 380 404 1.2E-15 T 06-07-2017 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 BWK49_RS03200 51e0d8b86ef795f9a2bc0dc985e5e88a 413 PRINTS PR00758 Arsenical pump membrane protein signature 347 372 1.2E-15 T 06-07-2017 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 BWK49_RS03200 51e0d8b86ef795f9a2bc0dc985e5e88a 413 PRINTS PR00758 Arsenical pump membrane protein signature 175 198 1.2E-15 T 06-07-2017 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 BWK49_RS03200 51e0d8b86ef795f9a2bc0dc985e5e88a 413 PRINTS PR00758 Arsenical pump membrane protein signature 102 126 1.2E-15 T 06-07-2017 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 BWK49_RS03200 51e0d8b86ef795f9a2bc0dc985e5e88a 413 Pfam PF02040 Arsenical pump membrane protein 5 402 2.1E-21 T 06-07-2017 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 BWK49_RS28630 1dd747a567111d82a9fc886e1751146a 265 Pfam PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus 125 171 8.2E-10 T 06-07-2017 IPR032528 Sigma 54 modulation/S30EA ribosomal protein, C-terminal BWK49_RS02640 affc0669f8efa045a3934b9d970164d0 154 SUPERFAMILY SSF89095 4 154 3.3E-33 T 06-07-2017 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 BWK49_RS02640 affc0669f8efa045a3934b9d970164d0 154 Pfam PF09424 Yqey-like protein 5 154 4.4E-47 T 06-07-2017 IPR019004 Uncharacterised domain YOR215C, mitochondrial BWK49_RS02640 affc0669f8efa045a3934b9d970164d0 154 Gene3D G3DSA:1.10.1510.10 3 93 5.4E-30 T 06-07-2017 BWK49_RS02640 affc0669f8efa045a3934b9d970164d0 154 Gene3D G3DSA:1.10.10.410 94 154 1.0E-17 T 06-07-2017 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal BWK49_RS26620 95cd28b3bb0c5217c31ea40cdb1a31e8 383 Gene3D G3DSA:1.10.10.10 281 373 1.7E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS26620 95cd28b3bb0c5217c31ea40cdb1a31e8 383 Pfam PF02602 Uroporphyrinogen-III synthase HemD 24 268 5.1E-39 T 06-07-2017 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 BWK49_RS26620 95cd28b3bb0c5217c31ea40cdb1a31e8 383 SMART SM00862 302 372 2.4E-11 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 BWK49_RS26620 95cd28b3bb0c5217c31ea40cdb1a31e8 383 Pfam PF00486 Transcriptional regulatory protein, C terminal 305 372 5.6E-11 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 BWK49_RS26620 95cd28b3bb0c5217c31ea40cdb1a31e8 383 SUPERFAMILY SSF69618 11 277 7.85E-53 T 06-07-2017 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 BWK49_RS26620 95cd28b3bb0c5217c31ea40cdb1a31e8 383 SUPERFAMILY SSF46894 284 372 1.25E-12 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 BWK49_RS26620 95cd28b3bb0c5217c31ea40cdb1a31e8 383 Gene3D G3DSA:3.40.50.10090 8 137 1.4E-28 T 06-07-2017 BWK49_RS26620 95cd28b3bb0c5217c31ea40cdb1a31e8 383 Gene3D G3DSA:3.40.50.10090 139 277 4.1E-30 T 06-07-2017 BWK49_RS15485 255ed49f50e69d5d85f3fb0ee782db72 70 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 1 66 2.0E-16 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 BWK49_RS15485 255ed49f50e69d5d85f3fb0ee782db72 70 Pfam PF04075 Domain of unknown function (DUF385) 1 64 6.2E-8 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 BWK49_RS21960 c2718229fb37e9510683bfd83160f1bd 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 67 7.2E-17 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS21960 c2718229fb37e9510683bfd83160f1bd 207 Gene3D G3DSA:1.10.10.60 12 67 5.5E-22 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS21960 c2718229fb37e9510683bfd83160f1bd 207 Gene3D G3DSA:1.10.357.10 68 206 1.4E-34 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS21960 c2718229fb37e9510683bfd83160f1bd 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 1.9E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS21960 c2718229fb37e9510683bfd83160f1bd 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 1.9E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS21960 c2718229fb37e9510683bfd83160f1bd 207 SUPERFAMILY SSF48498 89 206 2.67E-28 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS21960 c2718229fb37e9510683bfd83160f1bd 207 SUPERFAMILY SSF46689 11 74 5.67E-19 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS12585 a5f45ebe85c17615ee714cc1468b6949 520 Pfam PF01928 CYTH domain 12 143 1.1E-14 T 06-07-2017 IPR023577 CYTH domain Reactome: R-HSA-196819 BWK49_RS12585 a5f45ebe85c17615ee714cc1468b6949 520 Pfam PF05235 CHAD domain 244 470 5.7E-45 T 06-07-2017 IPR007899 CHAD domain BWK49_RS12585 a5f45ebe85c17615ee714cc1468b6949 520 SMART SM00880 244 502 1.8E-68 T 06-07-2017 IPR007899 CHAD domain BWK49_RS12585 a5f45ebe85c17615ee714cc1468b6949 520 SMART SM01118 11 227 1.0E-15 T 06-07-2017 IPR023577 CYTH domain Reactome: R-HSA-196819 BWK49_RS12585 a5f45ebe85c17615ee714cc1468b6949 520 SUPERFAMILY SSF55154 10 233 1.8E-45 T 06-07-2017 IPR033469 CYTH-like domain Reactome: R-HSA-196819 BWK49_RS12585 a5f45ebe85c17615ee714cc1468b6949 520 Gene3D G3DSA:2.40.320.10 10 240 5.6E-65 T 06-07-2017 IPR023577 CYTH domain Reactome: R-HSA-196819 BWK49_RS01095 66968bb8cb265847febdc0702624fb53 516 Gene3D G3DSA:2.102.10.10 465 513 2.2E-11 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS01095 66968bb8cb265847febdc0702624fb53 516 SUPERFAMILY SSF50022 466 513 1.44E-11 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS01095 66968bb8cb265847febdc0702624fb53 516 Pfam PF13483 Beta-lactamase superfamily domain 2 80 7.1E-7 T 06-07-2017 BWK49_RS01095 66968bb8cb265847febdc0702624fb53 516 Gene3D G3DSA:3.60.15.10 1 222 3.8E-15 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS01095 66968bb8cb265847febdc0702624fb53 516 SUPERFAMILY SSF56281 108 237 6.16E-16 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS01095 66968bb8cb265847febdc0702624fb53 516 SUPERFAMILY SSF56281 2 75 6.16E-16 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS01095 66968bb8cb265847febdc0702624fb53 516 Pfam PF00355 Rieske [2Fe-2S] domain 466 506 2.9E-7 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS06685 5ef8570a64dd52f5b19b3b8a9cc8dc3e 152 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 13 129 3.4E-10 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain BWK49_RS06685 5ef8570a64dd52f5b19b3b8a9cc8dc3e 152 Gene3D G3DSA:3.10.180.10 11 141 2.3E-31 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS06685 5ef8570a64dd52f5b19b3b8a9cc8dc3e 152 SUPERFAMILY SSF54593 8 132 4.56E-32 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS15050 0c3d00b5a3d868c0c6fc8b5a6b84113a 706 SUPERFAMILY SSF53300 521 693 6.67E-10 T 06-07-2017 IPR002035 von Willebrand factor, type A BWK49_RS15050 0c3d00b5a3d868c0c6fc8b5a6b84113a 706 Pfam PF13531 Bacterial extracellular solute-binding protein 189 470 5.6E-16 T 06-07-2017 BWK49_RS15050 0c3d00b5a3d868c0c6fc8b5a6b84113a 706 Gene3D G3DSA:3.40.50.410 586 693 3.4E-4 T 06-07-2017 IPR002035 von Willebrand factor, type A BWK49_RS15050 0c3d00b5a3d868c0c6fc8b5a6b84113a 706 SMART SM00327 512 706 6.2E-6 T 06-07-2017 IPR002035 von Willebrand factor, type A BWK49_RS11185 1605201413fded03e421ffb162b02b95 157 Gene3D G3DSA:1.20.120.520 9 138 3.1E-14 T 06-07-2017 BWK49_RS11185 1605201413fded03e421ffb162b02b95 157 Pfam PF01814 Hemerythrin HHE cation binding domain 8 123 4.1E-13 T 06-07-2017 IPR012312 Haemerythrin-like Reactome: R-HSA-390471 BWK49_RS07335 cfcc5ef64e1867488ac09c61841856fd 347 Pfam PF13439 Glycosyltransferase Family 4 15 160 1.4E-11 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 BWK49_RS07335 cfcc5ef64e1867488ac09c61841856fd 347 SUPERFAMILY SSF53756 12 341 5.89E-30 T 06-07-2017 BWK49_RS10420 d0a2a367a60185828bc7535f6f5b0a25 999 ProSitePatterns PS00012 Phosphopantetheine attachment site. 956 971 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site BWK49_RS10420 d0a2a367a60185828bc7535f6f5b0a25 999 Gene3D G3DSA:3.40.50.720 675 850 4.8E-26 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS10420 d0a2a367a60185828bc7535f6f5b0a25 999 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 103 406 2.4E-44 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain BWK49_RS10420 d0a2a367a60185828bc7535f6f5b0a25 999 Pfam PF00550 Phosphopantetheine attachment site 931 995 7.5E-10 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS10420 d0a2a367a60185828bc7535f6f5b0a25 999 Pfam PF00698 Acyl transferase domain 102 418 8.0E-50 T 06-07-2017 IPR014043 Acyl transferase BWK49_RS10420 d0a2a367a60185828bc7535f6f5b0a25 999 SUPERFAMILY SSF47336 927 998 3.93E-13 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS10420 d0a2a367a60185828bc7535f6f5b0a25 999 SUPERFAMILY SSF51735 675 886 1.22E-33 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS10420 d0a2a367a60185828bc7535f6f5b0a25 999 SUPERFAMILY SSF51735 480 662 2.32E-17 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS10420 d0a2a367a60185828bc7535f6f5b0a25 999 SUPERFAMILY SSF52151 292 388 2.43E-44 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 BWK49_RS10420 d0a2a367a60185828bc7535f6f5b0a25 999 SUPERFAMILY SSF52151 99 227 2.43E-44 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 BWK49_RS10420 d0a2a367a60185828bc7535f6f5b0a25 999 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 674 851 5.1E-16 T 06-07-2017 BWK49_RS10420 d0a2a367a60185828bc7535f6f5b0a25 999 SMART SM00823 Phosphopantetheine attachment site 929 998 5.1E-7 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS10420 d0a2a367a60185828bc7535f6f5b0a25 999 Pfam PF08659 KR domain 676 849 1.5E-39 T 06-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 BWK49_RS10420 d0a2a367a60185828bc7535f6f5b0a25 999 SUPERFAMILY SSF55048 227 290 4.58E-8 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 BWK49_RS10420 d0a2a367a60185828bc7535f6f5b0a25 999 Gene3D G3DSA:1.10.1200.10 927 998 1.5E-11 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS10420 d0a2a367a60185828bc7535f6f5b0a25 999 Gene3D G3DSA:3.40.366.10 100 221 1.9E-47 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 BWK49_RS10420 d0a2a367a60185828bc7535f6f5b0a25 999 Gene3D G3DSA:3.40.366.10 290 404 1.9E-47 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 BWK49_RS00810 7efc8b35972cf21622dcb6f83af6831c 404 Gene3D G3DSA:1.20.1250.20 25 196 1.3E-20 T 06-07-2017 BWK49_RS00810 7efc8b35972cf21622dcb6f83af6831c 404 SUPERFAMILY SSF103473 12 396 2.88E-28 T 06-07-2017 IPR020846 Major facilitator superfamily domain BWK49_RS00810 7efc8b35972cf21622dcb6f83af6831c 404 Pfam PF07690 Major Facilitator Superfamily 33 362 2.6E-19 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 BWK49_RS00810 7efc8b35972cf21622dcb6f83af6831c 404 ProSitePatterns PS00216 Sugar transport proteins signature 1. 78 95 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 BWK49_RS12630 d2787042665464f70d6056a9607caaec 994 SUPERFAMILY SSF81593 843 993 1.73E-36 T 06-07-2017 BWK49_RS12630 d2787042665464f70d6056a9607caaec 994 Pfam PF08335 GlnD PII-uridylyltransferase 336 483 5.6E-35 T 06-07-2017 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 BWK49_RS12630 d2787042665464f70d6056a9607caaec 994 Pfam PF08335 GlnD PII-uridylyltransferase 850 992 1.3E-20 T 06-07-2017 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 BWK49_RS12630 d2787042665464f70d6056a9607caaec 994 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 590 827 3.4E-65 T 06-07-2017 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 BWK49_RS12630 d2787042665464f70d6056a9607caaec 994 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 90 315 1.9E-37 T 06-07-2017 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 BWK49_RS12630 d2787042665464f70d6056a9607caaec 994 SUPERFAMILY SSF81593 329 483 3.3E-34 T 06-07-2017 BWK49_RS12630 d2787042665464f70d6056a9607caaec 994 SUPERFAMILY SSF81301 561 830 4.9E-62 T 06-07-2017 BWK49_RS12630 d2787042665464f70d6056a9607caaec 994 Hamap MF_00802 Glutamate-ammonia-ligase adenylyltransferase [glnE]. 86 983 16.978 T 06-07-2017 IPR023057 Glutamate-ammonia-ligase adenylyltransferase GO:0008882 BWK49_RS12630 d2787042665464f70d6056a9607caaec 994 Gene3D G3DSA:3.30.460.10 179 323 2.6E-45 T 06-07-2017 BWK49_RS12630 d2787042665464f70d6056a9607caaec 994 Gene3D G3DSA:3.30.460.10 675 835 2.6E-51 T 06-07-2017 BWK49_RS12630 d2787042665464f70d6056a9607caaec 994 SUPERFAMILY SSF81301 75 323 4.58E-59 T 06-07-2017 BWK49_RS03545 4cdba98d81ca6aa3c0872123ba08047f 255 PIRSF PIRSF006221 2 255 5.3E-51 T 06-07-2017 IPR016477 Fructosamine/Ketosamine-3-kinase Reactome: R-HSA-163841 BWK49_RS03545 4cdba98d81ca6aa3c0872123ba08047f 255 Pfam PF03881 Fructosamine kinase 4 249 1.2E-37 T 06-07-2017 IPR016477 Fructosamine/Ketosamine-3-kinase Reactome: R-HSA-163841 BWK49_RS03545 4cdba98d81ca6aa3c0872123ba08047f 255 SUPERFAMILY SSF56112 4 243 3.35E-35 T 06-07-2017 IPR011009 Protein kinase-like domain BWK49_RS03545 4cdba98d81ca6aa3c0872123ba08047f 255 Gene3D G3DSA:3.30.200.20 4 43 1.2E-4 T 06-07-2017 BWK49_RS03545 4cdba98d81ca6aa3c0872123ba08047f 255 Gene3D G3DSA:3.90.1200.10 55 232 3.9E-17 T 06-07-2017 BWK49_RS27440 4b294e8b912326812a2faad1cdffc95b 360 Gene3D G3DSA:3.50.50.60 175 197 1.5E-4 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS27440 4b294e8b912326812a2faad1cdffc95b 360 Gene3D G3DSA:3.40.50.1770 7 174 2.1E-53 T 06-07-2017 BWK49_RS27440 4b294e8b912326812a2faad1cdffc95b 360 SMART SM01003 9 139 1.5E-56 T 06-07-2017 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal BWK49_RS27440 4b294e8b912326812a2faad1cdffc95b 360 SUPERFAMILY SSF51735 139 314 1.65E-37 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS27440 4b294e8b912326812a2faad1cdffc95b 360 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 143 359 2.8E-65 T 06-07-2017 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain BWK49_RS27440 4b294e8b912326812a2faad1cdffc95b 360 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 9 139 1.2E-39 T 06-07-2017 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal BWK49_RS27440 4b294e8b912326812a2faad1cdffc95b 360 Gene3D G3DSA:3.40.50.1770 198 359 4.2E-34 T 06-07-2017 BWK49_RS27440 4b294e8b912326812a2faad1cdffc95b 360 SUPERFAMILY SSF52283 7 170 1.53E-46 T 06-07-2017 BWK49_RS27440 4b294e8b912326812a2faad1cdffc95b 360 SMART SM01002 148 310 9.4E-77 T 06-07-2017 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain BWK49_RS25320 a72acf192d13d4ab3d249b0a5fe8339d 33 Pfam PF08213 Mitochondrial domain of unknown function (DUF1713) 1 33 4.5E-12 T 06-07-2017 IPR013177 Domain of unknown function DUF1713 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS25320 a72acf192d13d4ab3d249b0a5fe8339d 33 SMART SM01155 1 33 2.8E-8 T 06-07-2017 IPR013177 Domain of unknown function DUF1713 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS03130 b35e401f9d6adca7a547a4c4a3349522 106 Gene3D G3DSA:3.30.70.900 4 102 1.8E-31 T 06-07-2017 BWK49_RS03130 b35e401f9d6adca7a547a4c4a3349522 106 Pfam PF03992 Antibiotic biosynthesis monooxygenase 4 76 7.1E-19 T 06-07-2017 IPR007138 Antibiotic biosynthesis monooxygenase domain BWK49_RS03130 b35e401f9d6adca7a547a4c4a3349522 106 SUPERFAMILY SSF54909 4 98 8.05E-24 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel BWK49_RS00640 05ec6c1145a129ba7bd5bdecd758f252 419 SUPERFAMILY SSF46689 223 300 1.8E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS00640 05ec6c1145a129ba7bd5bdecd758f252 419 Gene3D G3DSA:1.10.357.10 221 380 5.7E-28 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS00640 05ec6c1145a129ba7bd5bdecd758f252 419 Pfam PF00440 Bacterial regulatory proteins, tetR family 228 272 8.4E-15 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS00640 05ec6c1145a129ba7bd5bdecd758f252 419 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 68 8.8E-12 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS00640 05ec6c1145a129ba7bd5bdecd758f252 419 Gene3D G3DSA:1.10.357.10 13 212 7.0E-25 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS00640 05ec6c1145a129ba7bd5bdecd758f252 419 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 228 241 2.0E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS00640 05ec6c1145a129ba7bd5bdecd758f252 419 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 249 272 2.0E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS00640 05ec6c1145a129ba7bd5bdecd758f252 419 SUPERFAMILY SSF46689 13 80 2.84E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS09115 ef0f0f798f70c0fe77e3755cd5579e1e 351 Pfam PF03576 Peptidase family S58 3 337 9.3E-75 T 06-07-2017 IPR005321 Peptidase S58, DmpA BWK49_RS09115 ef0f0f798f70c0fe77e3755cd5579e1e 351 SUPERFAMILY SSF56266 2 346 7.32E-79 T 06-07-2017 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 BWK49_RS09115 ef0f0f798f70c0fe77e3755cd5579e1e 351 Gene3D G3DSA:3.60.70.12 2 342 1.5E-92 T 06-07-2017 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 BWK49_RS17290 3faae1239692ec6d1e339423d608dd6b 152 Gene3D G3DSA:3.40.30.10 2 150 2.9E-39 T 06-07-2017 IPR012336 Thioredoxin-like fold BWK49_RS17290 3faae1239692ec6d1e339423d608dd6b 152 Pfam PF00578 AhpC/TSA family 4 127 2.1E-31 T 06-07-2017 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 BWK49_RS17290 3faae1239692ec6d1e339423d608dd6b 152 PIRSF PIRSF000239 1 151 1.1E-20 T 06-07-2017 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 BWK49_RS17290 3faae1239692ec6d1e339423d608dd6b 152 SUPERFAMILY SSF52833 2 150 1.52E-41 T 06-07-2017 IPR012336 Thioredoxin-like fold BWK49_RS11315 02b6f158c8082c1e51e4c2f426081753 548 Pfam PF01061 ABC-2 type transporter 307 507 5.5E-17 T 06-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 BWK49_RS11315 02b6f158c8082c1e51e4c2f426081753 548 Pfam PF01061 ABC-2 type transporter 5 210 3.4E-11 T 06-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 BWK49_RS03030 b178d9252282a0432eda51fa3c99fd2f 337 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 101 2.1E-10 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 BWK49_RS03030 b178d9252282a0432eda51fa3c99fd2f 337 SUPERFAMILY SSF50129 1 176 5.35E-32 T 06-07-2017 IPR011032 GroES-like BWK49_RS03030 b178d9252282a0432eda51fa3c99fd2f 337 Pfam PF00107 Zinc-binding dehydrogenase 177 298 7.2E-14 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 BWK49_RS03030 b178d9252282a0432eda51fa3c99fd2f 337 Gene3D G3DSA:3.40.50.720 169 280 1.0E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS03030 b178d9252282a0432eda51fa3c99fd2f 337 Gene3D G3DSA:3.90.180.10 1 168 4.4E-29 T 06-07-2017 IPR011032 GroES-like BWK49_RS03030 b178d9252282a0432eda51fa3c99fd2f 337 SUPERFAMILY SSF51735 140 303 2.63E-31 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS28090 c3fad88cbb62267e11d7f3f5386216f2 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 136 164 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS28090 c3fad88cbb62267e11d7f3f5386216f2 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 6.4E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS28090 c3fad88cbb62267e11d7f3f5386216f2 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 6.4E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS28090 c3fad88cbb62267e11d7f3f5386216f2 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 6.4E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS28090 c3fad88cbb62267e11d7f3f5386216f2 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 168 6.4E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS28090 c3fad88cbb62267e11d7f3f5386216f2 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 139 6.4E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS28090 c3fad88cbb62267e11d7f3f5386216f2 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 74 85 1.7E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS28090 c3fad88cbb62267e11d7f3f5386216f2 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 129 137 1.7E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS28090 c3fad88cbb62267e11d7f3f5386216f2 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 168 1.7E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS28090 c3fad88cbb62267e11d7f3f5386216f2 253 Gene3D G3DSA:3.40.50.720 4 251 5.4E-56 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS28090 c3fad88cbb62267e11d7f3f5386216f2 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 248 3.4E-41 T 06-07-2017 BWK49_RS28090 c3fad88cbb62267e11d7f3f5386216f2 253 SUPERFAMILY SSF51735 6 251 1.01E-55 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS05100 476ddd110383056ce47ec44d7469b4d7 136 Pfam PF05423 Mycobacterium membrane protein 1 136 5.5E-42 T 06-07-2017 IPR008693 Transport accessory protein MmpS BWK49_RS25430 f6c680046045f51389ac1f42241f7c47 134 Pfam PF10783 Protein of unknown function (DUF2599) 30 127 1.2E-38 T 06-07-2017 IPR019719 Protein of unknown function DUF2599 BWK49_RS15345 ad617bd9f0c9a37a60fc533a878d48d8 562 Pfam PF14362 Domain of unknown function (DUF4407) 34 314 5.6E-49 T 06-07-2017 IPR025519 Protein of unknown function DUF4407 BWK49_RS05455 1762a504e64a916930eb1473288ab306 63 Gene3D G3DSA:3.30.420.10 2 50 5.4E-4 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS05455 1762a504e64a916930eb1473288ab306 63 SUPERFAMILY SSF53098 2 50 9.1E-5 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS06585 a5c78558acd19b28452c72763143428f 264 Pfam PF06737 Transglycosylase-like domain 39 114 6.5E-35 T 06-07-2017 IPR010618 Transglycosylase-like BWK49_RS06585 a5c78558acd19b28452c72763143428f 264 SUPERFAMILY SSF53955 39 116 8.21E-31 T 06-07-2017 IPR023346 Lysozyme-like domain BWK49_RS06585 a5c78558acd19b28452c72763143428f 264 Gene3D G3DSA:1.10.530.10 17 118 2.5E-41 T 06-07-2017 BWK49_RS18150 241c3a55198d1b2c32f8917826aa1a8c 257 SMART SM00382 34 236 1.6E-5 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS18150 241c3a55198d1b2c32f8917826aa1a8c 257 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 4 248 2.9E-102 T 06-07-2017 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524|GO:0006810 BWK49_RS18150 241c3a55198d1b2c32f8917826aa1a8c 257 SUPERFAMILY SSF52540 3 236 4.85E-40 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS18150 241c3a55198d1b2c32f8917826aa1a8c 257 Pfam PF00005 ABC transporter 25 176 4.5E-21 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 BWK49_RS18150 241c3a55198d1b2c32f8917826aa1a8c 257 Gene3D G3DSA:3.40.50.300 3 246 1.2E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS10180 1ddf5851ff0ccb7226f35bf767afee23 279 Gene3D G3DSA:3.90.260.10 170 270 2.5E-10 T 06-07-2017 IPR002931 Transglutaminase-like BWK49_RS10180 1ddf5851ff0ccb7226f35bf767afee23 279 SMART SM00460 167 234 3.9E-15 T 06-07-2017 IPR002931 Transglutaminase-like BWK49_RS10180 1ddf5851ff0ccb7226f35bf767afee23 279 Pfam PF01841 Transglutaminase-like superfamily 129 232 1.1E-22 T 06-07-2017 IPR002931 Transglutaminase-like BWK49_RS10180 1ddf5851ff0ccb7226f35bf767afee23 279 Pfam PF08379 Bacterial transglutaminase-like N-terminal region 4 82 5.1E-19 T 06-07-2017 IPR013589 Bacterial transglutaminase-like, N-terminal BWK49_RS10180 1ddf5851ff0ccb7226f35bf767afee23 279 SUPERFAMILY SSF54001 8 268 4.21E-33 T 06-07-2017 BWK49_RS18695 a0f959a8d553679b5f5cf2d9f41402cd 291 SUPERFAMILY SSF51735 1 157 2.7E-15 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS18695 a0f959a8d553679b5f5cf2d9f41402cd 291 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 1 286 8.3E-53 T 06-07-2017 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0015940|GO:0016491|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 BWK49_RS18695 a0f959a8d553679b5f5cf2d9f41402cd 291 Gene3D G3DSA:3.40.50.720 1 171 3.6E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS18695 a0f959a8d553679b5f5cf2d9f41402cd 291 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 165 285 6.0E-20 T 06-07-2017 IPR013752 Ketopantoate reductase, C-terminal domain GO:0016491|GO:0050661|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 BWK49_RS18695 a0f959a8d553679b5f5cf2d9f41402cd 291 Gene3D G3DSA:1.10.1040.10 172 285 1.5E-25 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 BWK49_RS18695 a0f959a8d553679b5f5cf2d9f41402cd 291 SUPERFAMILY SSF48179 165 285 4.42E-24 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 BWK49_RS18695 a0f959a8d553679b5f5cf2d9f41402cd 291 Pfam PF02558 Ketopantoate reductase PanE/ApbA 1 142 2.5E-28 T 06-07-2017 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 BWK49_RS08755 7db32a1b791c01915c53aa37cd1850ea 167 SMART SM00855 6 114 3.8E-11 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 BWK49_RS08755 7db32a1b791c01915c53aa37cd1850ea 167 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 7 80 3.3E-9 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 BWK49_RS08755 7db32a1b791c01915c53aa37cd1850ea 167 SUPERFAMILY SSF53254 6 146 2.36E-21 T 06-07-2017 IPR029033 Histidine phosphatase superfamily BWK49_RS08755 7db32a1b791c01915c53aa37cd1850ea 167 Gene3D G3DSA:3.40.50.1240 4 167 2.1E-49 T 06-07-2017 IPR029033 Histidine phosphatase superfamily BWK49_RS21525 81aeae5eb42395d1d523393b1980cc4a 184 Gene3D G3DSA:1.20.1290.10 43 180 4.2E-26 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 BWK49_RS21525 81aeae5eb42395d1d523393b1980cc4a 184 SUPERFAMILY SSF69118 10 180 1.96E-31 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 BWK49_RS21525 81aeae5eb42395d1d523393b1980cc4a 184 Pfam PF02627 Carboxymuconolactone decarboxylase family 52 129 3.2E-10 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 BWK49_RS03250 79a4255869d1a1abd4186dac89a91cb3 190 Gene3D G3DSA:1.10.357.10 55 184 5.8E-10 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS03250 79a4255869d1a1abd4186dac89a91cb3 190 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 57 3.4E-17 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS03250 79a4255869d1a1abd4186dac89a91cb3 190 SUPERFAMILY SSF46689 6 74 8.98E-19 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS03250 79a4255869d1a1abd4186dac89a91cb3 190 Gene3D G3DSA:1.10.10.60 8 54 1.4E-21 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS03250 79a4255869d1a1abd4186dac89a91cb3 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 1.9E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS03250 79a4255869d1a1abd4186dac89a91cb3 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 1.9E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS15625 530d3e07ef2f03af4e42c918ea123ac0 425 Pfam PF00174 Oxidoreductase molybdopterin binding domain 287 421 3.3E-22 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 BWK49_RS15625 530d3e07ef2f03af4e42c918ea123ac0 425 Gene3D G3DSA:3.90.420.10 275 421 4.6E-32 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 BWK49_RS15625 530d3e07ef2f03af4e42c918ea123ac0 425 SUPERFAMILY SSF56524 287 421 1.44E-31 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 BWK49_RS15625 530d3e07ef2f03af4e42c918ea123ac0 425 SUPERFAMILY SSF81342 66 190 1.05E-5 T 06-07-2017 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 BWK49_RS15625 530d3e07ef2f03af4e42c918ea123ac0 425 PRINTS PR00407 Eukaryotic molybdopterin domain signature 391 404 6.9E-7 T 06-07-2017 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 BWK49_RS15625 530d3e07ef2f03af4e42c918ea123ac0 425 PRINTS PR00407 Eukaryotic molybdopterin domain signature 374 390 6.9E-7 T 06-07-2017 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 BWK49_RS15625 530d3e07ef2f03af4e42c918ea123ac0 425 PRINTS PR00407 Eukaryotic molybdopterin domain signature 326 341 6.9E-7 T 06-07-2017 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 BWK49_RS00130 82751bc786cc02f30dbbee8c5f69a80a 155 Pfam PF16697 Inner membrane component of T3SS, cytoplasmic domain 66 154 1.7E-15 T 06-07-2017 IPR032030 YscD, cytoplasmic domain BWK49_RS00130 82751bc786cc02f30dbbee8c5f69a80a 155 Gene3D G3DSA:2.60.200.20 55 153 3.9E-24 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 BWK49_RS00130 82751bc786cc02f30dbbee8c5f69a80a 155 SUPERFAMILY SSF49879 53 153 4.4E-24 T 06-07-2017 IPR008984 SMAD/FHA domain GO:0005515 BWK49_RS00130 82751bc786cc02f30dbbee8c5f69a80a 155 SMART SM00240 82 132 8.7E-13 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 BWK49_RS03495 87f04d65908341a1c54384fd7ccb9df7 174 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 88 122 1.3E-4 T 06-07-2017 IPR001451 Hexapeptide repeat BWK49_RS03495 87f04d65908341a1c54384fd7ccb9df7 174 SUPERFAMILY SSF51161 1 158 1.8E-37 T 06-07-2017 IPR011004 Trimeric LpxA-like BWK49_RS03495 87f04d65908341a1c54384fd7ccb9df7 174 Gene3D G3DSA:2.160.10.10 4 165 7.1E-35 T 06-07-2017 BWK49_RS03625 1e6dd710c06d95b47b5f6383c0aa9583 384 Pfam PF02470 MlaD protein 41 119 6.8E-11 T 06-07-2017 IPR003399 Mce/MlaD BWK49_RS03625 1e6dd710c06d95b47b5f6383c0aa9583 384 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 13 305 1.8E-75 T 06-07-2017 IPR005693 Virulence factor Mce protein BWK49_RS08205 d3f1e3ceefadc37dc9c06dd7e92d7648 177 Pfam PF13577 SnoaL-like domain 12 133 1.3E-24 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain BWK49_RS08205 d3f1e3ceefadc37dc9c06dd7e92d7648 177 SUPERFAMILY SSF54427 5 172 1.24E-37 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS08205 d3f1e3ceefadc37dc9c06dd7e92d7648 177 Gene3D G3DSA:3.10.450.50 11 142 1.5E-30 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS02805 499e9480a48a785679bf1579f989f588 397 Pfam PF02674 Colicin V production protein 7 149 1.4E-13 T 06-07-2017 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 BWK49_RS02805 499e9480a48a785679bf1579f989f588 397 SUPERFAMILY SSF50494 193 384 2.38E-38 T 06-07-2017 IPR009003 Peptidase S1, PA clan BWK49_RS02805 499e9480a48a785679bf1579f989f588 397 Gene3D G3DSA:2.40.10.10 187 278 2.6E-18 T 06-07-2017 BWK49_RS02805 499e9480a48a785679bf1579f989f588 397 Gene3D G3DSA:2.40.10.10 279 383 7.0E-17 T 06-07-2017 BWK49_RS02805 499e9480a48a785679bf1579f989f588 397 PRINTS PR00834 HtrA/DegQ protease family signature 328 345 3.4E-12 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 BWK49_RS02805 499e9480a48a785679bf1579f989f588 397 PRINTS PR00834 HtrA/DegQ protease family signature 287 311 3.4E-12 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 BWK49_RS02805 499e9480a48a785679bf1579f989f588 397 PRINTS PR00834 HtrA/DegQ protease family signature 248 268 3.4E-12 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 BWK49_RS02805 499e9480a48a785679bf1579f989f588 397 PRINTS PR00834 HtrA/DegQ protease family signature 228 240 3.4E-12 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 BWK49_RS02805 499e9480a48a785679bf1579f989f588 397 Pfam PF13365 Trypsin-like peptidase domain 220 357 4.3E-25 T 06-07-2017 BWK49_RS15600 39f8868840a393396b1aeb2d3eb6afa6 156 Pfam PF01047 MarR family 38 76 5.1E-7 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 BWK49_RS15600 39f8868840a393396b1aeb2d3eb6afa6 156 SUPERFAMILY SSF46785 7 90 3.9E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS15600 39f8868840a393396b1aeb2d3eb6afa6 156 Gene3D G3DSA:1.10.10.10 7 80 3.3E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS18310 dafbda20ffee440043a62d5b74f2314e 358 Pfam PF01933 Uncharacterised protein family UPF0052 9 280 1.2E-69 T 06-07-2017 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 BWK49_RS18310 dafbda20ffee440043a62d5b74f2314e 358 Hamap MF_00973 Gluconeogenesis factor. 5 317 32.102 T 06-07-2017 IPR010119 Gluconeogenesis factor BWK49_RS18310 dafbda20ffee440043a62d5b74f2314e 358 Gene3D G3DSA:3.40.50.10680 82 314 2.5E-42 T 06-07-2017 BWK49_RS18310 dafbda20ffee440043a62d5b74f2314e 358 TIGRFAM TIGR01826 CofD_related: conserved hypothetical protein 9 314 3.5E-102 T 06-07-2017 IPR010119 Gluconeogenesis factor BWK49_RS18310 dafbda20ffee440043a62d5b74f2314e 358 SUPERFAMILY SSF142338 6 311 9.68E-84 T 06-07-2017 BWK49_RS02320 b4984c8fc7a64433f16794510d0d2083 202 Gene3D G3DSA:1.10.10.60 19 65 2.2E-19 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS02320 b4984c8fc7a64433f16794510d0d2083 202 SUPERFAMILY SSF46689 11 81 1.39E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS02320 b4984c8fc7a64433f16794510d0d2083 202 Gene3D G3DSA:1.10.357.10 66 195 6.4E-18 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS02320 b4984c8fc7a64433f16794510d0d2083 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 67 4.2E-16 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS02320 b4984c8fc7a64433f16794510d0d2083 202 ProSitePatterns PS01081 TetR-type HTH domain signature. 34 65 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site BWK49_RS02320 b4984c8fc7a64433f16794510d0d2083 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 35 7.5E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS02320 b4984c8fc7a64433f16794510d0d2083 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 66 7.5E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS23605 1dd9e5dd0bf7f00329c41a44211ef3b1 214 Pfam PF00881 Nitroreductase family 14 189 3.5E-21 T 06-07-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 BWK49_RS23605 1dd9e5dd0bf7f00329c41a44211ef3b1 214 Gene3D G3DSA:3.40.109.10 103 214 1.5E-35 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 BWK49_RS23605 1dd9e5dd0bf7f00329c41a44211ef3b1 214 Gene3D G3DSA:3.40.109.10 4 71 1.5E-35 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 BWK49_RS23605 1dd9e5dd0bf7f00329c41a44211ef3b1 214 SUPERFAMILY SSF55469 7 211 2.62E-35 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 BWK49_RS14415 53ae69ec26853b41af3e95d4d78dd31b 399 SUPERFAMILY SSF51679 1 341 1.18E-70 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS14415 53ae69ec26853b41af3e95d4d78dd31b 399 Gene3D G3DSA:3.20.20.30 1 341 2.4E-72 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS14415 53ae69ec26853b41af3e95d4d78dd31b 399 Pfam PF00296 Luciferase-like monooxygenase 1 304 1.6E-41 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS24110 c046061b6f3573040289dc811a4d1892 389 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 337 356 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 BWK49_RS24110 c046061b6f3573040289dc811a4d1892 389 Gene3D G3DSA:2.40.110.10 120 214 8.8E-38 T 06-07-2017 BWK49_RS24110 c046061b6f3573040289dc811a4d1892 389 SUPERFAMILY SSF47203 227 381 2.74E-53 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS24110 c046061b6f3573040289dc811a4d1892 389 PIRSF PIRSF016578 2 380 4.4E-17 T 06-07-2017 BWK49_RS24110 c046061b6f3573040289dc811a4d1892 389 Gene3D G3DSA:1.10.540.10 2 117 6.1E-33 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS24110 c046061b6f3573040289dc811a4d1892 389 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 115 1.6E-26 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS24110 c046061b6f3573040289dc811a4d1892 389 Gene3D G3DSA:1.20.140.10 215 380 3.6E-60 T 06-07-2017 BWK49_RS24110 c046061b6f3573040289dc811a4d1892 389 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 122 134 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 BWK49_RS24110 c046061b6f3573040289dc811a4d1892 389 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 229 377 6.8E-47 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS24110 c046061b6f3573040289dc811a4d1892 389 SUPERFAMILY SSF56645 2 242 2.88E-73 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS24110 c046061b6f3573040289dc811a4d1892 389 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 120 214 5.6E-24 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 BWK49_RS03915 6c65a4721b83d2c35378979e5f539d3a 555 SUPERFAMILY SSF51905 10 282 4.0E-39 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS03915 6c65a4721b83d2c35378979e5f539d3a 555 SUPERFAMILY SSF51905 491 553 4.0E-39 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS03915 6c65a4721b83d2c35378979e5f539d3a 555 Gene3D G3DSA:3.50.50.60 11 277 3.0E-69 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS03915 6c65a4721b83d2c35378979e5f539d3a 555 Gene3D G3DSA:3.50.50.60 488 553 3.0E-69 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS03915 6c65a4721b83d2c35378979e5f539d3a 555 Pfam PF00890 FAD binding domain 12 536 7.8E-108 T 06-07-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 BWK49_RS03915 6c65a4721b83d2c35378979e5f539d3a 555 PIRSF PIRSF036654 6 554 0.0 T 06-07-2017 IPR014614 Uncharacterised conserved protein UCP036654 GO:0016627|GO:0055114 BWK49_RS02075 b5887c1d0a62093739f448fc0fddfef3 332 SUPERFAMILY SSF56112 7 329 7.23E-49 T 06-07-2017 IPR011009 Protein kinase-like domain BWK49_RS02075 b5887c1d0a62093739f448fc0fddfef3 332 Pfam PF01636 Phosphotransferase enzyme family 17 253 4.9E-36 T 06-07-2017 IPR002575 Aminoglycoside phosphotransferase BWK49_RS02075 b5887c1d0a62093739f448fc0fddfef3 332 Gene3D G3DSA:3.90.1200.10 118 327 1.0E-33 T 06-07-2017 BWK49_RS03325 16039c2a7fadd708663d6ff634a6a2fb 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 96 107 1.6E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS03325 16039c2a7fadd708663d6ff634a6a2fb 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 158 1.6E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS03325 16039c2a7fadd708663d6ff634a6a2fb 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 170 189 1.6E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS03325 16039c2a7fadd708663d6ff634a6a2fb 262 Gene3D G3DSA:3.40.50.720 16 258 2.1E-74 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS03325 16039c2a7fadd708663d6ff634a6a2fb 262 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 26 257 3.1E-59 T 06-07-2017 BWK49_RS03325 16039c2a7fadd708663d6ff634a6a2fb 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 160 3.3E-33 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS03325 16039c2a7fadd708663d6ff634a6a2fb 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 21 38 3.3E-33 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS03325 16039c2a7fadd708663d6ff634a6a2fb 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 189 3.3E-33 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS03325 16039c2a7fadd708663d6ff634a6a2fb 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 191 208 3.3E-33 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS03325 16039c2a7fadd708663d6ff634a6a2fb 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 96 107 3.3E-33 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS03325 16039c2a7fadd708663d6ff634a6a2fb 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 225 245 3.3E-33 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS03325 16039c2a7fadd708663d6ff634a6a2fb 262 SUPERFAMILY SSF51735 17 258 5.5E-71 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS08060 1611dfe2a3579ac73082123ef0dd46ee 215 Gene3D G3DSA:3.40.109.10 12 209 7.0E-29 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 BWK49_RS08060 1611dfe2a3579ac73082123ef0dd46ee 215 Pfam PF00881 Nitroreductase family 20 186 1.4E-19 T 06-07-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 BWK49_RS08060 1611dfe2a3579ac73082123ef0dd46ee 215 SUPERFAMILY SSF55469 1 65 4.58E-32 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 BWK49_RS08060 1611dfe2a3579ac73082123ef0dd46ee 215 SUPERFAMILY SSF55469 97 211 4.58E-32 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 BWK49_RS10995 8edf3bf0ded552ac940fe8bc96603674 398 Gene3D G3DSA:3.20.20.140 9 36 1.6E-47 T 06-07-2017 BWK49_RS10995 8edf3bf0ded552ac940fe8bc96603674 398 Gene3D G3DSA:3.20.20.140 79 397 1.6E-47 T 06-07-2017 BWK49_RS10995 8edf3bf0ded552ac940fe8bc96603674 398 Pfam PF04909 Amidohydrolase 98 395 2.7E-19 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 BWK49_RS10995 8edf3bf0ded552ac940fe8bc96603674 398 SUPERFAMILY SSF51556 6 36 5.78E-53 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS10995 8edf3bf0ded552ac940fe8bc96603674 398 SUPERFAMILY SSF51556 92 395 5.78E-53 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS24465 428a5375b12fc60832bd2436cf6c91d2 312 SUPERFAMILY SSF52096 10 281 3.91E-51 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS24465 428a5375b12fc60832bd2436cf6c91d2 312 Gene3D G3DSA:3.90.226.10 8 257 2.8E-54 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS24465 428a5375b12fc60832bd2436cf6c91d2 312 Pfam PF00378 Enoyl-CoA hydratase/isomerase 22 84 1.2E-10 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 BWK49_RS24465 428a5375b12fc60832bd2436cf6c91d2 312 Pfam PF00378 Enoyl-CoA hydratase/isomerase 124 272 4.7E-17 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 BWK49_RS11745 5e86820594da4459cbb1a5daf1915863 349 Pfam PF01636 Phosphotransferase enzyme family 43 261 1.8E-16 T 06-07-2017 IPR002575 Aminoglycoside phosphotransferase BWK49_RS11745 5e86820594da4459cbb1a5daf1915863 349 SUPERFAMILY SSF56112 21 317 1.22E-25 T 06-07-2017 IPR011009 Protein kinase-like domain BWK49_RS11745 5e86820594da4459cbb1a5daf1915863 349 Gene3D G3DSA:3.90.1200.10 139 300 1.4E-15 T 06-07-2017 BWK49_RS27270 6b497f539c932cfb454c3664b6b810a7 289 Pfam PF02405 Permease MlaE 70 273 6.5E-50 T 06-07-2017 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 BWK49_RS19010 a485c85f5f10c0d3edbf31016e1db74d 257 TIGRFAM TIGR02422 protocat_beta: protocatechuate 3,4-dioxygenase, beta subunit 36 253 1.2E-109 T 06-07-2017 IPR012785 Protocatechuate 3,4-dioxygenase, beta subunit GO:0005506|GO:0018578|GO:0019619|GO:0055114 KEGG: 00362+1.13.11.3|KEGG: 00624+1.13.11.3 BWK49_RS19010 a485c85f5f10c0d3edbf31016e1db74d 257 Pfam PF00775 Dioxygenase 67 245 3.1E-57 T 06-07-2017 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 BWK49_RS19010 a485c85f5f10c0d3edbf31016e1db74d 257 SUPERFAMILY SSF49482 32 253 1.96E-70 T 06-07-2017 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 BWK49_RS19010 a485c85f5f10c0d3edbf31016e1db74d 257 Pfam PF12391 Protocatechuate 3,4-dioxygenase beta subunit N terminal 34 61 6.5E-11 T 06-07-2017 IPR024756 Protocatechuate 3,4-dioxygenase beta subunit, N-terminal KEGG: 00362+1.13.11.3|KEGG: 00624+1.13.11.3 BWK49_RS19010 a485c85f5f10c0d3edbf31016e1db74d 257 Gene3D G3DSA:2.60.130.10 35 253 1.1E-73 T 06-07-2017 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 BWK49_RS19010 a485c85f5f10c0d3edbf31016e1db74d 257 ProSitePatterns PS00083 Intradiol ring-cleavage dioxygenases signature. 97 125 - T 06-07-2017 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 BWK49_RS18315 3975db8b8fe662ca25f2166f0a8303a6 303 SUPERFAMILY SSF52540 21 171 6.35E-12 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS18315 3975db8b8fe662ca25f2166f0a8303a6 303 Pfam PF03668 P-loop ATPase protein family 19 303 5.0E-134 T 06-07-2017 IPR005337 RapZ-like family GO:0005524 BWK49_RS18315 3975db8b8fe662ca25f2166f0a8303a6 303 PIRSF PIRSF005052 19 303 1.3E-115 T 06-07-2017 IPR005337 RapZ-like family GO:0005524 BWK49_RS18315 3975db8b8fe662ca25f2166f0a8303a6 303 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 19 302 40.686 T 06-07-2017 IPR005337 RapZ-like family GO:0005524 BWK49_RS18315 3975db8b8fe662ca25f2166f0a8303a6 303 Gene3D G3DSA:3.40.50.300 16 173 1.4E-17 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS14805 778ead15e3e02bbfeabda5d7b47cbdb7 61 Pfam PF04324 BFD-like [2Fe-2S] binding domain 2 50 1.6E-9 T 06-07-2017 IPR007419 BFD-like [2Fe-2S]-binding domain BWK49_RS10015 dd4a4624256561c13b79ad6e8700fb89 425 PRINTS PR00359 B-class P450 signature 175 190 3.1E-43 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS10015 dd4a4624256561c13b79ad6e8700fb89 425 PRINTS PR00359 B-class P450 signature 302 313 3.1E-43 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS10015 dd4a4624256561c13b79ad6e8700fb89 425 PRINTS PR00359 B-class P450 signature 319 346 3.1E-43 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS10015 dd4a4624256561c13b79ad6e8700fb89 425 PRINTS PR00359 B-class P450 signature 220 242 3.1E-43 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS10015 dd4a4624256561c13b79ad6e8700fb89 425 PRINTS PR00359 B-class P450 signature 111 122 3.1E-43 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS10015 dd4a4624256561c13b79ad6e8700fb89 425 PRINTS PR00359 B-class P450 signature 369 378 3.1E-43 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS10015 dd4a4624256561c13b79ad6e8700fb89 425 PRINTS PR00359 B-class P450 signature 158 174 3.1E-43 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS10015 dd4a4624256561c13b79ad6e8700fb89 425 PRINTS PR00359 B-class P450 signature 378 389 3.1E-43 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS10015 dd4a4624256561c13b79ad6e8700fb89 425 PRINTS PR00359 B-class P450 signature 347 362 3.1E-43 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS10015 dd4a4624256561c13b79ad6e8700fb89 425 Gene3D G3DSA:1.10.630.10 29 425 9.5E-103 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS10015 dd4a4624256561c13b79ad6e8700fb89 425 SUPERFAMILY SSF48264 62 425 5.24E-75 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS10015 dd4a4624256561c13b79ad6e8700fb89 425 Pfam PF00067 Cytochrome P450 106 398 3.7E-13 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS20035 ed714895218538072bcb9081e46709ee 234 SUPERFAMILY SSF52317 24 231 4.28E-42 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like BWK49_RS20035 ed714895218538072bcb9081e46709ee 234 Gene3D G3DSA:3.40.50.880 20 231 2.2E-42 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like BWK49_RS20035 ed714895218538072bcb9081e46709ee 234 Pfam PF07722 Peptidase C26 1 212 4.3E-65 T 06-07-2017 IPR011697 Peptidase C26 GO:0006541|GO:0016787 BWK49_RS00740 175d329b8b3eb72b99222b4b5913e2c1 451 SUPERFAMILY SSF52777 77 154 7.23E-7 T 06-07-2017 BWK49_RS00740 175d329b8b3eb72b99222b4b5913e2c1 451 TIGRFAM TIGR02946 acyl_WS_DGAT: acyltransferase, WS/DGAT/MGAT 4 447 1.2E-142 T 06-07-2017 IPR014292 Acyltransferase, WS/DGAT/MGAT GO:0016746|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 BWK49_RS00740 175d329b8b3eb72b99222b4b5913e2c1 451 Pfam PF06974 Protein of unknown function (DUF1298) 299 445 7.3E-28 T 06-07-2017 IPR009721 O-acyltransferase WSD1, C-terminal GO:0004144 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 BWK49_RS00740 175d329b8b3eb72b99222b4b5913e2c1 451 SUPERFAMILY SSF52777 210 442 9.45E-6 T 06-07-2017 BWK49_RS00740 175d329b8b3eb72b99222b4b5913e2c1 451 Pfam PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain 5 259 1.1E-81 T 06-07-2017 IPR004255 O-acyltransferase, WSD1, N-terminal GO:0004144|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 BWK49_RS12245 da31f32d6a9ce7d3088d794b77323e77 133 Pfam PF04075 Domain of unknown function (DUF385) 33 99 1.4E-5 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 BWK49_RS12245 da31f32d6a9ce7d3088d794b77323e77 133 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 22 110 7.6E-16 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 BWK49_RS25215 9e1f8715650acedc9ccf1239c9140cca 276 Gene3D G3DSA:3.40.50.1820 33 275 2.9E-29 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS25215 9e1f8715650acedc9ccf1239c9140cca 276 SUPERFAMILY SSF53474 49 275 2.49E-25 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS25215 9e1f8715650acedc9ccf1239c9140cca 276 Pfam PF00756 Putative esterase 69 273 3.8E-7 T 06-07-2017 IPR000801 Putative esterase Reactome: R-HSA-156590 BWK49_RS16115 e1707d8e17d7ed38d40ae43c9d5faf14 149 Pfam PF04191 Phospholipid methyltransferase 34 131 1.2E-12 T 06-07-2017 IPR007318 Phospholipid methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825|Reactome: R-HSA-1483191 BWK49_RS25810 14650f5fb2a54360e7cad9a9d9a62fc1 418 Pfam PF02720 Domain of unknown function (DUF222) 22 306 9.5E-64 T 06-07-2017 IPR003870 Domain of unknown function DUF222 BWK49_RS25810 14650f5fb2a54360e7cad9a9d9a62fc1 418 Pfam PF01844 HNH endonuclease 314 352 1.8E-5 T 06-07-2017 IPR002711 HNH endonuclease GO:0003676|GO:0004519 BWK49_RS25810 14650f5fb2a54360e7cad9a9d9a62fc1 418 SMART SM00507 297 348 5.0E-10 T 06-07-2017 IPR003615 HNH nuclease BWK49_RS10455 ed102137312aa71b79061a786f603001 462 TIGRFAM TIGR03605 antibiot_sagB: SagB-type dehydrogenase domain 286 457 2.7E-45 T 06-07-2017 IPR020051 SagB-type dehydrogenase domain BWK49_RS10455 ed102137312aa71b79061a786f603001 462 Gene3D G3DSA:3.40.109.10 261 459 9.1E-20 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 BWK49_RS10455 ed102137312aa71b79061a786f603001 462 SUPERFAMILY SSF55469 358 459 2.36E-18 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 BWK49_RS10455 ed102137312aa71b79061a786f603001 462 SUPERFAMILY SSF55469 267 330 2.36E-18 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 BWK49_RS10455 ed102137312aa71b79061a786f603001 462 Pfam PF00881 Nitroreductase family 270 457 9.0E-19 T 06-07-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 BWK49_RS01515 bcee7d88e30b97d6316603b03e57732c 306 Pfam PF04072 Leucine carboxyl methyltransferase 19 202 3.9E-66 T 06-07-2017 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 BWK49_RS01515 bcee7d88e30b97d6316603b03e57732c 306 Gene3D G3DSA:3.40.50.150 13 237 2.5E-19 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS01515 bcee7d88e30b97d6316603b03e57732c 306 SUPERFAMILY SSF53335 15 290 9.14E-77 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS01515 bcee7d88e30b97d6316603b03e57732c 306 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 17 275 4.6E-82 T 06-07-2017 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 BWK49_RS10230 627579b83b123c7370d272140242f3ac 346 Pfam PF13531 Bacterial extracellular solute-binding protein 49 293 2.2E-36 T 06-07-2017 BWK49_RS10230 627579b83b123c7370d272140242f3ac 346 SUPERFAMILY SSF53850 46 342 3.88E-56 T 06-07-2017 BWK49_RS10230 627579b83b123c7370d272140242f3ac 346 Gene3D G3DSA:3.40.190.10 48 148 1.7E-12 T 06-07-2017 BWK49_RS10230 627579b83b123c7370d272140242f3ac 346 Gene3D G3DSA:3.40.190.10 149 291 8.9E-47 T 06-07-2017 BWK49_RS10230 627579b83b123c7370d272140242f3ac 346 TIGRFAM TIGR00971 3a0106s03: sulfate ABC transporter, sulfate-binding protein 63 331 1.8E-47 T 06-07-2017 IPR005669 Thiosulphate/Sulfate-binding protein GO:0008272|GO:0015419 BWK49_RS00880 b39dec467bc940a4dc9b47d2f066d397 552 Pfam PF00082 Subtilase family 239 484 9.1E-20 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 BWK49_RS00880 b39dec467bc940a4dc9b47d2f066d397 552 Gene3D G3DSA:3.40.50.200 65 144 2.2E-67 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 BWK49_RS00880 b39dec467bc940a4dc9b47d2f066d397 552 Gene3D G3DSA:3.40.50.200 238 492 2.2E-67 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 BWK49_RS00880 b39dec467bc940a4dc9b47d2f066d397 552 TIGRFAM TIGR03921 T7SS_mycosin: type VII secretion-associated serine protease mycosin 234 550 7.3E-87 T 06-07-2017 IPR023834 Type VII secretion system peptidase S8A, mycosin-1 BWK49_RS00880 b39dec467bc940a4dc9b47d2f066d397 552 SUPERFAMILY SSF52743 66 143 5.71E-47 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 BWK49_RS00880 b39dec467bc940a4dc9b47d2f066d397 552 SUPERFAMILY SSF52743 236 493 5.71E-47 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 BWK49_RS00880 b39dec467bc940a4dc9b47d2f066d397 552 PRINTS PR00723 Subtilisin serine protease family (S8) signature 90 109 1.6E-9 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related BWK49_RS00880 b39dec467bc940a4dc9b47d2f066d397 552 PRINTS PR00723 Subtilisin serine protease family (S8) signature 125 138 1.6E-9 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related BWK49_RS00880 b39dec467bc940a4dc9b47d2f066d397 552 PRINTS PR00723 Subtilisin serine protease family (S8) signature 434 450 1.6E-9 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related BWK49_RS00880 b39dec467bc940a4dc9b47d2f066d397 552 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 95 105 - T 06-07-2017 IPR023827 Peptidase S8, subtilisin, Asp-active site BWK49_RS25920 9c21fe01a7adb6c36b711c6cd6a8b5c4 719 PIRSF PIRSF006107 5 716 1.2E-169 T 06-07-2017 IPR016475 Phosphate acetyltransferase, bacteria GO:0008959 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 BWK49_RS25920 9c21fe01a7adb6c36b711c6cd6a8b5c4 719 TIGRFAM TIGR00651 pta: phosphate acetyltransferase 408 709 7.8E-125 T 06-07-2017 IPR004614 Phosphate acetyltransferase GO:0016407 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 BWK49_RS25920 9c21fe01a7adb6c36b711c6cd6a8b5c4 719 Gene3D G3DSA:3.40.1390.20 224 368 3.0E-31 T 06-07-2017 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like BWK49_RS25920 9c21fe01a7adb6c36b711c6cd6a8b5c4 719 SUPERFAMILY SSF75138 229 353 2.2E-21 T 06-07-2017 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like BWK49_RS25920 9c21fe01a7adb6c36b711c6cd6a8b5c4 719 Gene3D G3DSA:3.40.50.300 8 208 3.1E-8 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS25920 9c21fe01a7adb6c36b711c6cd6a8b5c4 719 SUPERFAMILY SSF53659 393 712 8.22E-97 T 06-07-2017 BWK49_RS25920 9c21fe01a7adb6c36b711c6cd6a8b5c4 719 Pfam PF07085 DRTGG domain 235 346 5.8E-24 T 06-07-2017 IPR010766 DRTGG KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 BWK49_RS25920 9c21fe01a7adb6c36b711c6cd6a8b5c4 719 Gene3D G3DSA:3.40.50.10750 527 685 9.6E-66 T 06-07-2017 BWK49_RS25920 9c21fe01a7adb6c36b711c6cd6a8b5c4 719 Pfam PF13500 AAA domain 8 208 2.1E-15 T 06-07-2017 BWK49_RS25920 9c21fe01a7adb6c36b711c6cd6a8b5c4 719 Pfam PF01515 Phosphate acetyl/butaryl transferase 392 709 3.7E-132 T 06-07-2017 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 BWK49_RS25920 9c21fe01a7adb6c36b711c6cd6a8b5c4 719 SUPERFAMILY SSF52540 8 209 1.33E-11 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS10010 fbb9935683f53e9bdb2fe502a5a735fe 216 Gene3D G3DSA:1.10.357.10 70 210 1.5E-26 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS10010 fbb9935683f53e9bdb2fe502a5a735fe 216 SUPERFAMILY SSF46689 16 86 1.2E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS10010 fbb9935683f53e9bdb2fe502a5a735fe 216 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 73 1.7E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS10010 fbb9935683f53e9bdb2fe502a5a735fe 216 SUPERFAMILY SSF48498 94 209 2.97E-29 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS10010 fbb9935683f53e9bdb2fe502a5a735fe 216 ProSitePatterns PS01081 TetR-type HTH domain signature. 40 71 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site BWK49_RS10010 fbb9935683f53e9bdb2fe502a5a735fe 216 Gene3D G3DSA:1.10.10.60 15 69 1.1E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS16150 8475b37a7c59dd5e1e467f2f1be9c8c5 115 Pfam PF05305 Protein of unknown function (DUF732) 17 106 1.1E-23 T 06-07-2017 IPR007969 Domain of unknown function DUF732 BWK49_RS06845 fcb90e7bae04af878428070a970d01a6 408 Pfam PF01566 Natural resistance-associated macrophage protein 32 380 3.5E-109 T 06-07-2017 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 BWK49_RS06845 fcb90e7bae04af878428070a970d01a6 408 Hamap MF_00221 Divalent metal cation transporter MntH [mntH]. 3 406 33.575 T 06-07-2017 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 BWK49_RS06845 fcb90e7bae04af878428070a970d01a6 408 TIGRFAM TIGR01197 nramp: metal ion transporter, metal ion (Mn2+/Fe2+) transporter (Nramp) family 13 374 1.9E-84 T 06-07-2017 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 BWK49_RS06845 fcb90e7bae04af878428070a970d01a6 408 PRINTS PR00447 Natural resistance-associated macrophage protein signature 91 117 1.6E-25 T 06-07-2017 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 BWK49_RS06845 fcb90e7bae04af878428070a970d01a6 408 PRINTS PR00447 Natural resistance-associated macrophage protein signature 119 138 1.6E-25 T 06-07-2017 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 BWK49_RS06845 fcb90e7bae04af878428070a970d01a6 408 PRINTS PR00447 Natural resistance-associated macrophage protein signature 194 217 1.6E-25 T 06-07-2017 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 BWK49_RS06845 fcb90e7bae04af878428070a970d01a6 408 PRINTS PR00447 Natural resistance-associated macrophage protein signature 350 369 1.6E-25 T 06-07-2017 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 BWK49_RS02175 e86210fe0d994e342dcc7231991864e9 228 Gene3D G3DSA:1.10.3720.10 10 197 8.3E-21 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS02175 e86210fe0d994e342dcc7231991864e9 228 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 208 1.5E-14 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS02175 e86210fe0d994e342dcc7231991864e9 228 SUPERFAMILY SSF161098 11 195 5.49E-29 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS21505 94a943fd4639bb0b00e97395d2a748d3 141 Gene3D G3DSA:1.20.1250.20 81 114 7.1E-4 T 06-07-2017 BWK49_RS21505 94a943fd4639bb0b00e97395d2a748d3 141 Gene3D G3DSA:1.20.1250.20 2 36 7.1E-4 T 06-07-2017 BWK49_RS27210 4c33eee242b27c2c0d577a2283645ad1 369 Pfam PF09992 Phosphodiester glycosidase 150 347 2.3E-8 T 06-07-2017 IPR018711 Phosphodiester glycosidase BWK49_RS28425 0c6b39a741a01bb5011da90aee4f41a0 385 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 66 84 - T 06-07-2017 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 BWK49_RS28425 0c6b39a741a01bb5011da90aee4f41a0 385 SUPERFAMILY SSF53686 42 346 1.96E-69 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme BWK49_RS28425 0c6b39a741a01bb5011da90aee4f41a0 385 Gene3D G3DSA:3.40.50.1100 71 172 4.4E-26 T 06-07-2017 BWK49_RS28425 0c6b39a741a01bb5011da90aee4f41a0 385 Gene3D G3DSA:3.40.50.1100 173 340 6.0E-38 T 06-07-2017 BWK49_RS28425 0c6b39a741a01bb5011da90aee4f41a0 385 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 44 326 7.0E-52 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme BWK49_RS27060 89f6d9494184dc910fd4eef82cdbbdc3 240 Pfam PF01936 NYN domain 37 200 2.3E-6 T 06-07-2017 IPR021139 NYN domain, limkain-b1-type BWK49_RS27060 89f6d9494184dc910fd4eef82cdbbdc3 240 Gene3D G3DSA:3.40.50.1010 37 204 9.8E-7 T 06-07-2017 IPR029060 PIN domain-like BWK49_RS05805 94cc4992a3fa635df411d15a1a2dc5bc 141 SUPERFAMILY SSF54427 1 139 2.99E-37 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS05805 94cc4992a3fa635df411d15a1a2dc5bc 141 Pfam PF13577 SnoaL-like domain 4 127 4.2E-26 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain BWK49_RS05805 94cc4992a3fa635df411d15a1a2dc5bc 141 Gene3D G3DSA:3.10.450.50 5 139 2.1E-43 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS02025 f222a7911b92087e4090b0f801f677f7 211 SUPERFAMILY SSF46689 11 81 6.67E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS02025 f222a7911b92087e4090b0f801f677f7 211 SUPERFAMILY SSF48498 90 198 1.08E-13 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS02025 f222a7911b92087e4090b0f801f677f7 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 68 6.9E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS02025 f222a7911b92087e4090b0f801f677f7 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 24 37 6.9E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS02025 f222a7911b92087e4090b0f801f677f7 211 Gene3D G3DSA:1.10.357.10 10 208 1.8E-32 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS02025 f222a7911b92087e4090b0f801f677f7 211 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 70 4.2E-17 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS08370 1d6f6c28ea55f73af0a174e6b30b8847 546 Pfam PF13556 PucR C-terminal helix-turn-helix domain 469 527 1.0E-20 T 06-07-2017 IPR025736 PucR C-terminal helix-turn-helix domain BWK49_RS05190 31bbcde4a7c4cf3f4c0b35669e85741c 338 SUPERFAMILY SSF51679 13 315 1.83E-57 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS05190 31bbcde4a7c4cf3f4c0b35669e85741c 338 Gene3D G3DSA:3.20.20.30 9 321 4.9E-59 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS05190 31bbcde4a7c4cf3f4c0b35669e85741c 338 Pfam PF00296 Luciferase-like monooxygenase 11 304 3.1E-60 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS10620 6678696ef94b198fda131cfecc36d513 99 SUPERFAMILY SSF140459 8 84 9.94E-24 T 06-07-2017 BWK49_RS10620 6678696ef94b198fda131cfecc36d513 99 Pfam PF00934 PE family 1 93 7.4E-33 T 06-07-2017 IPR000084 PE-PGRS family, N-terminal BWK49_RS08690 a949253174febd5f7269ac375fea2664 376 Pfam PF01494 FAD binding domain 3 343 3.6E-20 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 BWK49_RS08690 a949253174febd5f7269ac375fea2664 376 SUPERFAMILY SSF51905 268 351 5.18E-48 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS08690 a949253174febd5f7269ac375fea2664 376 SUPERFAMILY SSF51905 4 169 5.18E-48 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS08690 a949253174febd5f7269ac375fea2664 376 Gene3D G3DSA:3.50.50.60 4 174 2.2E-29 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS08690 a949253174febd5f7269ac375fea2664 376 Gene3D G3DSA:3.50.50.60 269 346 2.2E-29 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS08690 a949253174febd5f7269ac375fea2664 376 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 296 312 7.6E-15 T 06-07-2017 BWK49_RS08690 a949253174febd5f7269ac375fea2664 376 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 148 163 7.6E-15 T 06-07-2017 BWK49_RS08690 a949253174febd5f7269ac375fea2664 376 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 281 296 7.6E-15 T 06-07-2017 BWK49_RS08690 a949253174febd5f7269ac375fea2664 376 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 7.6E-15 T 06-07-2017 BWK49_RS17445 58e1e9e6a458d5b907a2c19ec599f21e 243 Gene3D G3DSA:3.90.1720.10 32 162 5.0E-32 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain BWK49_RS17445 58e1e9e6a458d5b907a2c19ec599f21e 243 Pfam PF00877 NlpC/P60 family 51 162 2.4E-25 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain BWK49_RS17445 58e1e9e6a458d5b907a2c19ec599f21e 243 SUPERFAMILY SSF54001 33 151 2.31E-23 T 06-07-2017 BWK49_RS03630 7f2a2b0638f05302ea571ebc0164c691 573 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 9 297 5.5E-78 T 06-07-2017 IPR005693 Virulence factor Mce protein BWK49_RS03630 7f2a2b0638f05302ea571ebc0164c691 573 Pfam PF02470 MlaD protein 39 114 1.1E-16 T 06-07-2017 IPR003399 Mce/MlaD BWK49_RS13625 282addddd4e7a11612a40b837b77dc3d 319 SUPERFAMILY SSF51735 4 257 5.85E-55 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS13625 282addddd4e7a11612a40b837b77dc3d 319 Gene3D G3DSA:3.40.50.720 4 252 2.8E-57 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS13625 282addddd4e7a11612a40b837b77dc3d 319 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 143 159 2.5E-18 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS13625 282addddd4e7a11612a40b837b77dc3d 319 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 187 2.5E-18 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS13625 282addddd4e7a11612a40b837b77dc3d 319 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 189 206 2.5E-18 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS13625 282addddd4e7a11612a40b837b77dc3d 319 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 96 107 2.5E-18 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS13625 282addddd4e7a11612a40b837b77dc3d 319 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 168 187 1.9E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS13625 282addddd4e7a11612a40b837b77dc3d 319 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 96 107 1.9E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS13625 282addddd4e7a11612a40b837b77dc3d 319 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 157 1.9E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS13625 282addddd4e7a11612a40b837b77dc3d 319 Pfam PF00106 short chain dehydrogenase 10 207 4.6E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS19020 a1725d12d270c54158f41e9b66934f9e 323 Gene3D G3DSA:2.102.10.10 204 308 3.7E-26 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS19020 a1725d12d270c54158f41e9b66934f9e 323 SUPERFAMILY SSF50022 162 313 2.75E-28 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS19020 a1725d12d270c54158f41e9b66934f9e 323 Pfam PF09990 Predicted membrane protein (DUF2231) 107 194 3.8E-5 T 06-07-2017 IPR019251 Domain of unknown function DUF2231, transmembrane BWK49_RS19020 a1725d12d270c54158f41e9b66934f9e 323 Pfam PF00355 Rieske [2Fe-2S] domain 206 292 3.8E-17 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS08675 3bd9937d06575a0086964e39562e593b 409 Gene3D G3DSA:1.10.630.10 9 408 2.1E-102 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS08675 3bd9937d06575a0086964e39562e593b 409 Pfam PF00067 Cytochrome P450 279 379 1.5E-14 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS08675 3bd9937d06575a0086964e39562e593b 409 SUPERFAMILY SSF48264 15 408 4.32E-81 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS08675 3bd9937d06575a0086964e39562e593b 409 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 351 360 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 BWK49_RS08675 3bd9937d06575a0086964e39562e593b 409 PRINTS PR00359 B-class P450 signature 299 326 1.9E-41 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS08675 3bd9937d06575a0086964e39562e593b 409 PRINTS PR00359 B-class P450 signature 349 358 1.9E-41 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS08675 3bd9937d06575a0086964e39562e593b 409 PRINTS PR00359 B-class P450 signature 155 170 1.9E-41 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS08675 3bd9937d06575a0086964e39562e593b 409 PRINTS PR00359 B-class P450 signature 282 293 1.9E-41 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS08675 3bd9937d06575a0086964e39562e593b 409 PRINTS PR00359 B-class P450 signature 138 154 1.9E-41 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS08675 3bd9937d06575a0086964e39562e593b 409 PRINTS PR00359 B-class P450 signature 358 369 1.9E-41 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS08675 3bd9937d06575a0086964e39562e593b 409 PRINTS PR00359 B-class P450 signature 199 221 1.9E-41 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS08675 3bd9937d06575a0086964e39562e593b 409 PRINTS PR00359 B-class P450 signature 92 103 1.9E-41 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS11160 e69e3cd0e081c1ee388ef3801165d8b9 341 SUPERFAMILY SSF55469 22 96 1.7E-8 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 BWK49_RS11160 e69e3cd0e081c1ee388ef3801165d8b9 341 SUPERFAMILY SSF55469 129 338 1.71E-9 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 BWK49_RS11160 e69e3cd0e081c1ee388ef3801165d8b9 341 Gene3D G3DSA:3.40.109.10 197 198 5.2E-28 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 BWK49_RS11160 e69e3cd0e081c1ee388ef3801165d8b9 341 Gene3D G3DSA:3.40.109.10 247 338 5.2E-28 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 BWK49_RS11160 e69e3cd0e081c1ee388ef3801165d8b9 341 Gene3D G3DSA:3.40.109.10 22 84 5.2E-28 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 BWK49_RS11160 e69e3cd0e081c1ee388ef3801165d8b9 341 Pfam PF00881 Nitroreductase family 133 316 3.2E-5 T 06-07-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 BWK49_RS15090 46bf0efbf7632849ea0204566d77ffdf 160 Gene3D G3DSA:2.60.200.20 54 151 7.5E-30 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 BWK49_RS15090 46bf0efbf7632849ea0204566d77ffdf 160 SUPERFAMILY SSF49879 51 147 5.36E-32 T 06-07-2017 IPR008984 SMAD/FHA domain GO:0005515 BWK49_RS15090 46bf0efbf7632849ea0204566d77ffdf 160 Pfam PF00498 FHA domain 78 140 1.8E-19 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 BWK49_RS15090 46bf0efbf7632849ea0204566d77ffdf 160 SMART SM00240 76 126 9.6E-16 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 BWK49_RS03520 fe7f8d17749c8c6da6baaaf49d071c7a 343 Pfam PF00296 Luciferase-like monooxygenase 14 324 5.9E-72 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS03520 fe7f8d17749c8c6da6baaaf49d071c7a 343 Gene3D G3DSA:3.20.20.30 1 338 6.2E-77 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS03520 fe7f8d17749c8c6da6baaaf49d071c7a 343 SUPERFAMILY SSF51679 1 340 3.4E-69 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS03520 fe7f8d17749c8c6da6baaaf49d071c7a 343 TIGRFAM TIGR03559 F420_Rv3520c: probable F420-dependent oxidoreductase, Rv3520c family 2 329 1.5E-154 T 06-07-2017 IPR019951 F420-dependent oxidoreductase-predicted, Rv3520c BWK49_RS16185 9f7a6266f04a84317b971a03c4283112 99 Pfam PF00934 PE family 1 93 1.8E-29 T 06-07-2017 IPR000084 PE-PGRS family, N-terminal BWK49_RS16185 9f7a6266f04a84317b971a03c4283112 99 SUPERFAMILY SSF140459 8 84 3.66E-23 T 06-07-2017 BWK49_RS16490 ac85884d26fc11921a7dca731b498996 416 Pfam PF07690 Major Facilitator Superfamily 19 362 4.4E-22 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 BWK49_RS16490 ac85884d26fc11921a7dca731b498996 416 Gene3D G3DSA:1.20.1250.20 210 404 8.0E-10 T 06-07-2017 BWK49_RS16490 ac85884d26fc11921a7dca731b498996 416 Gene3D G3DSA:1.20.1250.20 16 196 4.8E-22 T 06-07-2017 BWK49_RS16490 ac85884d26fc11921a7dca731b498996 416 SUPERFAMILY SSF103473 16 405 1.57E-36 T 06-07-2017 IPR020846 Major facilitator superfamily domain BWK49_RS19100 4ac381f1a86c170c97be7d1b50f26957 261 SUPERFAMILY SSF56281 11 248 2.99E-16 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS19100 4ac381f1a86c170c97be7d1b50f26957 261 Gene3D G3DSA:3.60.15.10 6 257 4.6E-38 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS19100 4ac381f1a86c170c97be7d1b50f26957 261 Pfam PF12706 Beta-lactamase superfamily domain 25 223 1.5E-13 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS26210 54e31636671cf10573b45bde4ea710cf 314 Gene3D G3DSA:3.60.130.10 6 300 2.6E-81 T 06-07-2017 BWK49_RS26210 54e31636671cf10573b45bde4ea710cf 314 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 13 289 2.8E-54 T 06-07-2017 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 BWK49_RS26210 54e31636671cf10573b45bde4ea710cf 314 SUPERFAMILY SSF51197 11 296 6.87E-77 T 06-07-2017 BWK49_RS17315 a6a31fcb8c12e82d4d33b084ffaab4b3 247 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 3 244 31.43 T 06-07-2017 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 BWK49_RS17315 a6a31fcb8c12e82d4d33b084ffaab4b3 247 SUPERFAMILY SSF51366 3 243 9.42E-61 T 06-07-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 BWK49_RS17315 a6a31fcb8c12e82d4d33b084ffaab4b3 247 Pfam PF00977 Histidine biosynthesis protein 4 237 1.3E-60 T 06-07-2017 IPR006062 Histidine biosynthesis GO:0000105 BWK49_RS17315 a6a31fcb8c12e82d4d33b084ffaab4b3 247 Gene3D G3DSA:3.20.20.70 4 244 1.7E-69 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 BWK49_RS17315 a6a31fcb8c12e82d4d33b084ffaab4b3 247 TIGRFAM TIGR01919 hisA-trpF: bifunctional HisA/TrpF protein 2 245 8.9E-131 T 06-07-2017 IPR010188 Bifunctional HisA/TrpF GO:0000105|GO:0000162|GO:0003949|GO:0004640|GO:0005737 KEGG: 00340+5.3.1.16 BWK49_RS01455 343bf9b512965088ce5f0a185c780949 447 Pfam PF02470 MlaD protein 44 118 9.8E-15 T 06-07-2017 IPR003399 Mce/MlaD BWK49_RS01455 343bf9b512965088ce5f0a185c780949 447 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 147 412 1.6E-85 T 06-07-2017 IPR024516 Mammalian cell entry, C-terminal BWK49_RS01455 343bf9b512965088ce5f0a185c780949 447 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 14 295 2.5E-67 T 06-07-2017 IPR005693 Virulence factor Mce protein BWK49_RS28185 2a3124c97810f01052490c8cc29b04e0 147 Pfam PF13581 Histidine kinase-like ATPase domain 16 137 3.9E-19 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS28185 2a3124c97810f01052490c8cc29b04e0 147 SUPERFAMILY SSF55874 20 137 7.78E-8 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS27895 a116b2c36723bd6111a7dff52b1baae1 201 Gene3D G3DSA:1.10.357.10 22 199 6.1E-28 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS27895 a116b2c36723bd6111a7dff52b1baae1 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 69 1.2E-14 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS27895 a116b2c36723bd6111a7dff52b1baae1 201 SUPERFAMILY SSF46689 21 87 7.48E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS27895 a116b2c36723bd6111a7dff52b1baae1 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 68 7.1E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS27895 a116b2c36723bd6111a7dff52b1baae1 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 24 37 7.1E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS19155 f4c125cfda576f6b5f3a2795855b076d 422 Gene3D G3DSA:3.20.20.140 6 371 1.2E-45 T 06-07-2017 BWK49_RS19155 f4c125cfda576f6b5f3a2795855b076d 422 SUPERFAMILY SSF51556 4 33 1.08E-56 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS19155 f4c125cfda576f6b5f3a2795855b076d 422 SUPERFAMILY SSF51556 61 370 1.08E-56 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS19155 f4c125cfda576f6b5f3a2795855b076d 422 Pfam PF04909 Amidohydrolase 101 369 1.7E-25 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 BWK49_RS24060 a260d3c32914de95db27707f467649c3 373 Pfam PF01757 Acyltransferase family 13 330 7.6E-15 T 06-07-2017 IPR002656 Acyltransferase 3 GO:0016747 BWK49_RS09830 770517284f7764ff432c93c331388956 137 Gene3D G3DSA:3.10.129.10 5 135 1.6E-32 T 06-07-2017 IPR029069 HotDog domain BWK49_RS09830 770517284f7764ff432c93c331388956 137 Pfam PF13279 Thioesterase-like superfamily 11 114 2.3E-9 T 06-07-2017 BWK49_RS09830 770517284f7764ff432c93c331388956 137 SUPERFAMILY SSF54637 5 135 9.26E-23 T 06-07-2017 IPR029069 HotDog domain BWK49_RS05680 04ae75fb6e27c41fd0fbd0553716accb 316 Gene3D G3DSA:3.40.1090.10 3 277 1.2E-72 T 06-07-2017 BWK49_RS05680 04ae75fb6e27c41fd0fbd0553716accb 316 SUPERFAMILY SSF52151 6 269 9.16E-52 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 BWK49_RS05680 04ae75fb6e27c41fd0fbd0553716accb 316 Pfam PF01734 Patatin-like phospholipase 9 189 4.5E-24 T 06-07-2017 IPR002641 Patatin/Phospholipase A2-related GO:0006629 BWK49_RS29175 72b3d740f25b4fc2bfff62146c9a41a7 348 TIGRFAM TIGR03299 LGT_TIGR03299: phage/plasmid-like protein TIGR03299 17 345 2.1E-56 T 06-07-2017 IPR017686 Phage/plasmid-like protein BWK49_RS29175 72b3d740f25b4fc2bfff62146c9a41a7 348 Pfam PF06067 Domain of unknown function (DUF932) 94 323 9.5E-55 T 06-07-2017 IPR026325 Protein of unknown function DUF932 BWK49_RS01435 8cb4dd56079f3b0fc2f8a476ffaa07e7 379 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 16 303 8.3E-72 T 06-07-2017 IPR005693 Virulence factor Mce protein BWK49_RS01435 8cb4dd56079f3b0fc2f8a476ffaa07e7 379 Pfam PF02470 MlaD protein 48 119 2.7E-11 T 06-07-2017 IPR003399 Mce/MlaD BWK49_RS01435 8cb4dd56079f3b0fc2f8a476ffaa07e7 379 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 172 298 8.9E-10 T 06-07-2017 IPR024516 Mammalian cell entry, C-terminal BWK49_RS12115 5680d4e7d83e7e6be172a7ee52274fbf 329 SUPERFAMILY SSF53474 26 301 1.49E-39 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS12115 5680d4e7d83e7e6be172a7ee52274fbf 329 Pfam PF12697 Alpha/beta hydrolase family 43 298 1.0E-10 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS12115 5680d4e7d83e7e6be172a7ee52274fbf 329 Gene3D G3DSA:3.40.50.1820 17 302 1.2E-33 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS12575 53b5c52861f55543f4a7496d13f535a2 236 Pfam PF09859 Oxygenase, catalysing oxidative methylation of damaged DNA 64 235 1.1E-76 T 06-07-2017 IPR018655 Protein of unknown function DUF2086 BWK49_RS20600 65b8ba9a114297d1acb4a76c46675d58 381 SUPERFAMILY SSF140459 2 173 6.54E-65 T 06-07-2017 BWK49_RS20600 65b8ba9a114297d1acb4a76c46675d58 381 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 297 376 4.6E-20 T 06-07-2017 IPR022171 PPE family, C-terminal BWK49_RS20600 65b8ba9a114297d1acb4a76c46675d58 381 Pfam PF00823 PPE family 5 159 8.0E-63 T 06-07-2017 IPR000030 PPE family BWK49_RS11975 8c766f85ba646dda36b53a7c3e747c63 237 Pfam PF01988 VIT family 22 229 5.1E-57 T 06-07-2017 IPR008217 Ccc1 family BWK49_RS04195 e80ea579443167fe6440876c16d6b7cf 166 Gene3D G3DSA:3.40.140.10 3 136 7.2E-35 T 06-07-2017 BWK49_RS04195 e80ea579443167fe6440876c16d6b7cf 166 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 50 87 - T 06-07-2017 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 BWK49_RS04195 e80ea579443167fe6440876c16d6b7cf 166 SUPERFAMILY SSF53927 4 119 2.17E-33 T 06-07-2017 IPR016193 Cytidine deaminase-like GO:0003824 BWK49_RS04195 e80ea579443167fe6440876c16d6b7cf 166 Pfam PF14437 MafB19-like deaminase 6 97 1.6E-18 T 06-07-2017 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 BWK49_RS15070 de90706f8aacc41f9bc92d2bf253e7fd 941 SUPERFAMILY SSF53383 10 438 3.96E-96 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase BWK49_RS15070 de90706f8aacc41f9bc92d2bf253e7fd 941 TIGRFAM TIGR00461 gcvP: glycine dehydrogenase 10 934 0.0 T 06-07-2017 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 BWK49_RS15070 de90706f8aacc41f9bc92d2bf253e7fd 941 Gene3D G3DSA:3.40.640.10 488 726 8.2E-36 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 BWK49_RS15070 de90706f8aacc41f9bc92d2bf253e7fd 941 Gene3D G3DSA:3.40.640.10 87 304 1.0E-14 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 BWK49_RS15070 de90706f8aacc41f9bc92d2bf253e7fd 941 Hamap MF_00711 Glycine dehydrogenase (decarboxylating) [gcvP]. 1 940 24.876 T 06-07-2017 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 BWK49_RS15070 de90706f8aacc41f9bc92d2bf253e7fd 941 SUPERFAMILY SSF53383 913 936 9.57E-94 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase BWK49_RS15070 de90706f8aacc41f9bc92d2bf253e7fd 941 SUPERFAMILY SSF53383 467 870 9.57E-94 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase BWK49_RS15070 de90706f8aacc41f9bc92d2bf253e7fd 941 Pfam PF02347 Glycine cleavage system P-protein 10 438 1.0E-182 T 06-07-2017 IPR020580 Glycine cleavage system P-protein, N-terminal GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 BWK49_RS15070 de90706f8aacc41f9bc92d2bf253e7fd 941 Pfam PF02347 Glycine cleavage system P-protein 464 720 3.6E-9 T 06-07-2017 IPR020580 Glycine cleavage system P-protein, N-terminal GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 BWK49_RS12360 49d04e9a14854ee842811ffb69e65c62 435 Pfam PF00067 Cytochrome P450 113 397 1.1E-16 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS12360 49d04e9a14854ee842811ffb69e65c62 435 PRINTS PR00359 B-class P450 signature 183 198 8.6E-47 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS12360 49d04e9a14854ee842811ffb69e65c62 435 PRINTS PR00359 B-class P450 signature 166 182 8.6E-47 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS12360 49d04e9a14854ee842811ffb69e65c62 435 PRINTS PR00359 B-class P450 signature 117 128 8.6E-47 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS12360 49d04e9a14854ee842811ffb69e65c62 435 PRINTS PR00359 B-class P450 signature 383 394 8.6E-47 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS12360 49d04e9a14854ee842811ffb69e65c62 435 PRINTS PR00359 B-class P450 signature 225 247 8.6E-47 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS12360 49d04e9a14854ee842811ffb69e65c62 435 PRINTS PR00359 B-class P450 signature 374 383 8.6E-47 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS12360 49d04e9a14854ee842811ffb69e65c62 435 PRINTS PR00359 B-class P450 signature 307 318 8.6E-47 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS12360 49d04e9a14854ee842811ffb69e65c62 435 PRINTS PR00359 B-class P450 signature 352 367 8.6E-47 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS12360 49d04e9a14854ee842811ffb69e65c62 435 PRINTS PR00359 B-class P450 signature 324 351 8.6E-47 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS12360 49d04e9a14854ee842811ffb69e65c62 435 SUPERFAMILY SSF48264 47 433 1.44E-82 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS12360 49d04e9a14854ee842811ffb69e65c62 435 Gene3D G3DSA:1.10.630.10 43 433 1.7E-107 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS17145 1d2ac977c9937f34c69cf08603dcc664 296 TIGRFAM TIGR02778 ligD_pol: DNA ligase D, polymerase domain 6 249 2.6E-77 T 06-07-2017 IPR014145 DNA ligase D, polymerase domain BWK49_RS09805 204eaeff812357780bfbc8b7b08cf60a 85 TIGRFAM TIGR02116 toxin_Txe_YoeB: addiction module toxin, Txe/YoeB family 5 84 2.9E-33 T 06-07-2017 IPR009614 Toxin YoeB GO:0004519|GO:0006401 BWK49_RS09805 204eaeff812357780bfbc8b7b08cf60a 85 Pfam PF06769 YoeB-like toxin of bacterial type II toxin-antitoxin system 5 84 3.7E-37 T 06-07-2017 IPR009614 Toxin YoeB GO:0004519|GO:0006401 BWK49_RS09805 204eaeff812357780bfbc8b7b08cf60a 85 SUPERFAMILY SSF143011 1 83 1.83E-25 T 06-07-2017 BWK49_RS00525 042bacf99ae60dc6ba565e0e0cd647ed 140 Pfam PF00011 Hsp20/alpha crystallin family 32 128 5.6E-21 T 06-07-2017 IPR002068 Alpha crystallin/Hsp20 domain BWK49_RS00525 042bacf99ae60dc6ba565e0e0cd647ed 140 SUPERFAMILY SSF49764 5 129 1.12E-28 T 06-07-2017 IPR008978 HSP20-like chaperone BWK49_RS00525 042bacf99ae60dc6ba565e0e0cd647ed 140 Gene3D G3DSA:2.60.40.790 6 129 3.3E-26 T 06-07-2017 IPR008978 HSP20-like chaperone BWK49_RS28175 3676039472726cf116f50d55bc33ce9a 297 SUPERFAMILY SSF51569 4 295 2.62E-95 T 06-07-2017 BWK49_RS28175 3676039472726cf116f50d55bc33ce9a 297 Gene3D G3DSA:3.20.20.70 4 295 4.7E-100 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 BWK49_RS28175 3676039472726cf116f50d55bc33ce9a 297 Pfam PF00274 Fructose-bisphosphate aldolase class-I 10 182 2.1E-8 T 06-07-2017 IPR000741 Fructose-bisphosphate aldolase, class-I GO:0004332|GO:0006096 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385|Reactome: R-HSA-70171|Reactome: R-HSA-70263 BWK49_RS26575 e1498e2405dd72f087b4fa18a041bfa5 463 Gene3D G3DSA:1.20.1250.20 245 455 1.9E-15 T 06-07-2017 BWK49_RS26575 e1498e2405dd72f087b4fa18a041bfa5 463 Gene3D G3DSA:1.20.1250.20 50 240 5.5E-9 T 06-07-2017 BWK49_RS26575 e1498e2405dd72f087b4fa18a041bfa5 463 Pfam PF07690 Major Facilitator Superfamily 57 416 3.2E-13 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 BWK49_RS26575 e1498e2405dd72f087b4fa18a041bfa5 463 TIGRFAM TIGR00886 2A0108: nitrite transporter 45 412 1.2E-101 T 06-07-2017 IPR004737 Nitrate transporter GO:0015112|GO:0015113|GO:0015706|GO:0015707|GO:0016021 BWK49_RS26575 e1498e2405dd72f087b4fa18a041bfa5 463 SUPERFAMILY SSF103473 25 454 4.71E-40 T 06-07-2017 IPR020846 Major facilitator superfamily domain BWK49_RS02400 c27ff0901dcea0bb65df0670c85e4e6a 211 SUPERFAMILY SSF52499 7 208 2.35E-46 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 BWK49_RS02400 c27ff0901dcea0bb65df0670c85e4e6a 211 Pfam PF00857 Isochorismatase family 14 189 1.9E-36 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 BWK49_RS02400 c27ff0901dcea0bb65df0670c85e4e6a 211 Gene3D G3DSA:3.40.50.850 6 209 4.7E-51 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 BWK49_RS09865 7c58ed364e5e023ca4b8c4d170faa055 170 Pfam PF17174 Domain of unknown function (DUF5130) 29 164 3.6E-62 T 06-07-2017 IPR033437 Protein of unknown function DUF5130 BWK49_RS14925 6297a3058f150a8017975059df9e3748 342 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 72 86 - T 06-07-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 BWK49_RS14925 6297a3058f150a8017975059df9e3748 342 Gene3D G3DSA:3.40.50.720 184 288 4.6E-8 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS14925 6297a3058f150a8017975059df9e3748 342 SUPERFAMILY SSF51735 152 310 4.98E-28 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS14925 6297a3058f150a8017975059df9e3748 342 TIGRFAM TIGR02822 adh_fam_2: zinc-binding alcohol dehydrogenase family protein 12 341 5.3E-197 T 06-07-2017 IPR014187 Alcohol dehydrogenase, zinc-binding type 2 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396 BWK49_RS14925 6297a3058f150a8017975059df9e3748 342 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 39 146 2.7E-29 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 BWK49_RS14925 6297a3058f150a8017975059df9e3748 342 Gene3D G3DSA:3.90.180.10 7 183 3.0E-56 T 06-07-2017 IPR011032 GroES-like BWK49_RS14925 6297a3058f150a8017975059df9e3748 342 SUPERFAMILY SSF50129 6 182 3.3E-48 T 06-07-2017 IPR011032 GroES-like BWK49_RS14925 6297a3058f150a8017975059df9e3748 342 SMART SM00829 19 340 0.0064 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 BWK49_RS04830 c6e6d152307240a81e160be05dc5c383 74 Pfam PF00872 Transposase, Mutator family 13 69 9.4E-8 T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 BWK49_RS18630 97c66c8dac0b9d0db86990547d2633c6 223 SUPERFAMILY SSF54909 26 108 4.88E-9 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel BWK49_RS18630 97c66c8dac0b9d0db86990547d2633c6 223 Gene3D G3DSA:3.30.70.900 41 81 5.8E-4 T 06-07-2017 BWK49_RS18630 97c66c8dac0b9d0db86990547d2633c6 223 SUPERFAMILY SSF54909 126 189 2.56E-5 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel BWK49_RS18630 97c66c8dac0b9d0db86990547d2633c6 223 Pfam PF03992 Antibiotic biosynthesis monooxygenase 23 81 5.3E-5 T 06-07-2017 IPR007138 Antibiotic biosynthesis monooxygenase domain BWK49_RS15720 af70c30a64d2d1b4eb1ff9bafdc5c95a 295 SUPERFAMILY SSF53474 22 293 2.16E-57 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS15720 af70c30a64d2d1b4eb1ff9bafdc5c95a 295 Gene3D G3DSA:3.40.50.1820 14 293 6.4E-57 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS15720 af70c30a64d2d1b4eb1ff9bafdc5c95a 295 PRINTS PR00111 Alpha/beta hydrolase fold signature 124 137 6.4E-19 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS15720 af70c30a64d2d1b4eb1ff9bafdc5c95a 295 PRINTS PR00111 Alpha/beta hydrolase fold signature 67 82 6.4E-19 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS15720 af70c30a64d2d1b4eb1ff9bafdc5c95a 295 PRINTS PR00111 Alpha/beta hydrolase fold signature 110 123 6.4E-19 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS15720 af70c30a64d2d1b4eb1ff9bafdc5c95a 295 PRINTS PR00111 Alpha/beta hydrolase fold signature 238 252 6.4E-19 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS15720 af70c30a64d2d1b4eb1ff9bafdc5c95a 295 Pfam PF12697 Alpha/beta hydrolase family 41 284 8.8E-22 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS00765 f37f0a343ce33f3c6cb0d4283a48878d 117 SUPERFAMILY SSF54593 9 115 3.89E-19 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS00765 f37f0a343ce33f3c6cb0d4283a48878d 117 Gene3D G3DSA:3.10.180.10 8 114 7.4E-21 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS00765 f37f0a343ce33f3c6cb0d4283a48878d 117 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 109 1.6E-9 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain BWK49_RS12390 6ea65839f86d44db3f75e34101974ff2 207 SMART SM00849 23 186 8.1E-35 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS12390 6ea65839f86d44db3f75e34101974ff2 207 SUPERFAMILY SSF56281 11 199 7.85E-44 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS12390 6ea65839f86d44db3f75e34101974ff2 207 Gene3D G3DSA:3.60.15.10 23 195 6.0E-44 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS12390 6ea65839f86d44db3f75e34101974ff2 207 Pfam PF00753 Metallo-beta-lactamase superfamily 24 186 2.4E-21 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS00710 0ece54a044dcd6e4b9598fd2b17939a2 139 Pfam PF13581 Histidine kinase-like ATPase domain 8 127 1.7E-20 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS00710 0ece54a044dcd6e4b9598fd2b17939a2 139 SUPERFAMILY SSF55874 20 126 1.19E-5 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS18325 774e9a3b174c5dfbd1749a837add3967 390 Pfam PF08007 Cupin superfamily protein 16 253 1.8E-51 T 06-07-2017 IPR003347 JmjC domain BWK49_RS18325 774e9a3b174c5dfbd1749a837add3967 390 SUPERFAMILY SSF51197 8 283 6.45E-45 T 06-07-2017 BWK49_RS18325 774e9a3b174c5dfbd1749a837add3967 390 Gene3D G3DSA:2.60.120.650 9 222 2.9E-35 T 06-07-2017 BWK49_RS18685 7a2da0a25b168ae886194e980c157cfd 143 Gene3D G3DSA:2.30.110.10 33 102 3.6E-7 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 BWK49_RS18685 7a2da0a25b168ae886194e980c157cfd 143 Pfam PF04075 Domain of unknown function (DUF385) 15 138 6.0E-40 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 BWK49_RS18685 7a2da0a25b168ae886194e980c157cfd 143 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 29 140 2.2E-31 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 BWK49_RS18685 7a2da0a25b168ae886194e980c157cfd 143 SUPERFAMILY SSF50475 33 136 1.28E-9 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 BWK49_RS17505 849292836a0146165be9b2f34d62571b 634 SUPERFAMILY SSF69593 128 301 7.85E-6 T 06-07-2017 BWK49_RS17505 849292836a0146165be9b2f34d62571b 634 PIRSF PIRSF000437 3 633 1.6E-145 T 06-07-2017 IPR022284 Glycerol-3-phosphate O-acyltransferase/Dihydroxyacetone phosphate acyltransferase GO:0008374|GO:0044255 KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587|Reactome: R-HSA-1483166 BWK49_RS17505 849292836a0146165be9b2f34d62571b 634 SMART SM00563 123 250 4.3E-4 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 BWK49_RS17505 849292836a0146165be9b2f34d62571b 634 Pfam PF01553 Acyltransferase 118 247 9.2E-8 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 BWK49_RS08440 93d710f93448534e504c5d0323fa5f17 385 Pfam PF00823 PPE family 7 163 3.1E-59 T 06-07-2017 IPR000030 PPE family BWK49_RS08440 93d710f93448534e504c5d0323fa5f17 385 SUPERFAMILY SSF140459 4 175 4.97E-61 T 06-07-2017 BWK49_RS08440 93d710f93448534e504c5d0323fa5f17 385 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 305 381 3.4E-14 T 06-07-2017 IPR022171 PPE family, C-terminal BWK49_RS22220 e3237e20c030e6a090347c07936f3da7 179 Pfam PF01899 Na+/H+ ion antiporter subunit 19 169 6.8E-23 T 06-07-2017 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 BWK49_RS18210 7592bc446f3c7d0bc0fdaf2385083d04 373 ProSitePatterns PS01054 Transaldolase signature 1. 44 52 - T 06-07-2017 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336 BWK49_RS18210 7592bc446f3c7d0bc0fdaf2385083d04 373 SUPERFAMILY SSF51569 9 362 7.57E-82 T 06-07-2017 BWK49_RS18210 7592bc446f3c7d0bc0fdaf2385083d04 373 TIGRFAM TIGR00876 tal_mycobact: transaldolase 14 363 2.0E-179 T 06-07-2017 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 BWK49_RS18210 7592bc446f3c7d0bc0fdaf2385083d04 373 ProSitePatterns PS00958 Transaldolase active site. 140 157 - T 06-07-2017 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336 BWK49_RS18210 7592bc446f3c7d0bc0fdaf2385083d04 373 Pfam PF00923 Transaldolase 18 363 1.6E-86 T 06-07-2017 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336 BWK49_RS18210 7592bc446f3c7d0bc0fdaf2385083d04 373 Gene3D G3DSA:3.20.20.70 7 362 9.5E-126 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 BWK49_RS18210 7592bc446f3c7d0bc0fdaf2385083d04 373 PIRSF PIRSF036915 1 373 3.4E-179 T 06-07-2017 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 BWK49_RS18210 7592bc446f3c7d0bc0fdaf2385083d04 373 Hamap MF_00493 Transaldolase [tal]. 1 373 165.012 T 06-07-2017 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 BWK49_RS25850 62d2f03e65b7160ed2eb4690fa0fb951 110 Pfam PF04505 Interferon-induced transmembrane protein 22 89 1.3E-26 T 06-07-2017 IPR007593 CD225/Dispanin family GO:0009607|GO:0016021 BWK49_RS19430 ea78f8e589dfb34dcbac53bd390525f3 138 Gene3D G3DSA:3.30.1330.40 4 124 2.7E-39 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like BWK49_RS19430 ea78f8e589dfb34dcbac53bd390525f3 138 Pfam PF01042 Endoribonuclease L-PSP 13 122 1.7E-25 T 06-07-2017 IPR006175 YjgF/YER057c/UK114 family BWK49_RS19430 ea78f8e589dfb34dcbac53bd390525f3 138 SUPERFAMILY SSF55298 5 125 2.04E-34 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like BWK49_RS10020 77fb1c3463971174258dd91f7b967776 282 Gene3D G3DSA:3.30.1600.10 121 198 2.8E-17 T 06-07-2017 IPR026591 Sirtuin family, catalytic core small domain BWK49_RS10020 77fb1c3463971174258dd91f7b967776 282 Gene3D G3DSA:3.30.1600.10 36 69 2.8E-17 T 06-07-2017 IPR026591 Sirtuin family, catalytic core small domain BWK49_RS10020 77fb1c3463971174258dd91f7b967776 282 Hamap MF_01967 NAD-dependent protein deacetylase [cobB]. 2 272 65.051 T 06-07-2017 IPR026587 Sirtuin, class II BWK49_RS10020 77fb1c3463971174258dd91f7b967776 282 SUPERFAMILY SSF52467 165 276 1.01E-74 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain BWK49_RS10020 77fb1c3463971174258dd91f7b967776 282 SUPERFAMILY SSF52467 16 136 1.01E-74 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain BWK49_RS10020 77fb1c3463971174258dd91f7b967776 282 Pfam PF02146 Sir2 family 25 227 1.7E-40 T 06-07-2017 IPR003000 Sirtuin family GO:0070403 BWK49_RS10020 77fb1c3463971174258dd91f7b967776 282 Gene3D G3DSA:3.40.50.1220 204 277 3.2E-42 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain BWK49_RS10020 77fb1c3463971174258dd91f7b967776 282 Gene3D G3DSA:3.40.50.1220 16 35 3.2E-42 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain BWK49_RS10020 77fb1c3463971174258dd91f7b967776 282 Gene3D G3DSA:3.40.50.1220 83 120 3.2E-42 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain BWK49_RS13020 d0e51264489e987e206d253138f24f10 202 SUPERFAMILY SSF55729 119 198 4.79E-12 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase BWK49_RS13020 d0e51264489e987e206d253138f24f10 202 Pfam PF00583 Acetyltransferase (GNAT) family 115 178 1.4E-7 T 06-07-2017 IPR000182 GNAT domain GO:0008080 BWK49_RS13020 d0e51264489e987e206d253138f24f10 202 Gene3D G3DSA:3.40.630.30 24 200 9.1E-13 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase BWK49_RS03705 84b74a071c7d8ef3f7401e2ce8e6221c 261 SUPERFAMILY SSF53474 2 255 2.1E-40 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS03705 84b74a071c7d8ef3f7401e2ce8e6221c 261 Gene3D G3DSA:3.40.50.1820 1 256 1.3E-50 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS03705 84b74a071c7d8ef3f7401e2ce8e6221c 261 Pfam PF12697 Alpha/beta hydrolase family 1 247 4.6E-17 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS03705 84b74a071c7d8ef3f7401e2ce8e6221c 261 PRINTS PR00412 Epoxide hydrolase signature 5 23 7.8E-5 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS03705 84b74a071c7d8ef3f7401e2ce8e6221c 261 PRINTS PR00412 Epoxide hydrolase signature 25 40 7.8E-5 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS03705 84b74a071c7d8ef3f7401e2ce8e6221c 261 PRINTS PR00412 Epoxide hydrolase signature 231 253 7.8E-5 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS17460 19a5cf670024a789767dad646a4283ef 769 Pfam PF00128 Alpha amylase, catalytic domain 31 104 3.1E-17 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 BWK49_RS17460 19a5cf670024a789767dad646a4283ef 769 Gene3D G3DSA:3.30.1590.10 100 213 1.7E-34 T 06-07-2017 BWK49_RS17460 19a5cf670024a789767dad646a4283ef 769 SUPERFAMILY SSF51445 7 677 6.17E-130 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily BWK49_RS17460 19a5cf670024a789767dad646a4283ef 769 Gene3D G3DSA:3.20.20.80 7 99 6.1E-74 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 BWK49_RS17460 19a5cf670024a789767dad646a4283ef 769 Gene3D G3DSA:3.20.20.80 601 711 6.1E-74 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 BWK49_RS17460 19a5cf670024a789767dad646a4283ef 769 Gene3D G3DSA:3.20.20.80 463 502 6.1E-74 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 BWK49_RS17460 19a5cf670024a789767dad646a4283ef 769 Gene3D G3DSA:3.20.20.80 227 302 6.1E-74 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 BWK49_RS17460 19a5cf670024a789767dad646a4283ef 769 TIGRFAM TIGR02401 trehalose_TreY: malto-oligosyltrehalose synthase 5 765 2.3E-278 T 06-07-2017 IPR012767 Malto-oligosyltrehalose synthase MetaCyc: PWY-2661 BWK49_RS17460 19a5cf670024a789767dad646a4283ef 769 SMART SM00642 20 655 3.3E-8 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 BWK49_RS17460 19a5cf670024a789767dad646a4283ef 769 Gene3D G3DSA:1.10.10.470 503 593 4.9E-26 T 06-07-2017 IPR013797 Maltooligosyl trehalose synthase, N-terminal MetaCyc: PWY-2661 BWK49_RS20610 68149a45d852343bae017da38582887e 389 Pfam PF00823 PPE family 6 161 1.4E-58 T 06-07-2017 IPR000030 PPE family BWK49_RS20610 68149a45d852343bae017da38582887e 389 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 306 385 2.4E-19 T 06-07-2017 IPR022171 PPE family, C-terminal BWK49_RS20610 68149a45d852343bae017da38582887e 389 SUPERFAMILY SSF140459 3 175 1.23E-59 T 06-07-2017 BWK49_RS07160 ecb085085824db71c4f6fe28d4ec18f9 232 Pfam PF04116 Fatty acid hydroxylase superfamily 53 197 1.5E-15 T 06-07-2017 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0006633|GO:0016491|GO:0055114 BWK49_RS16720 57ae4b13368e98615c62668a0fbd5e98 71 Pfam PF03966 Trm112p-like protein 3 41 1.6E-8 T 06-07-2017 IPR005651 Uncharacterised protein family UPF0434/Trm112 BWK49_RS16720 57ae4b13368e98615c62668a0fbd5e98 71 SUPERFAMILY SSF158997 1 56 1.15E-15 T 06-07-2017 BWK49_RS16720 57ae4b13368e98615c62668a0fbd5e98 71 Gene3D G3DSA:2.20.25.10 9 63 4.4E-16 T 06-07-2017 BWK49_RS20705 9595ffe925269c1b3a2021ccf2029160 111 Pfam PF13453 Transcription factor zinc-finger 10 48 5.5E-16 T 06-07-2017 IPR027392 Transcription factor zinc-finger BWK49_RS10980 bbf09c0d3541869fe771469bb515f81d 300 Gene3D G3DSA:3.20.20.30 4 296 1.7E-58 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS10980 bbf09c0d3541869fe771469bb515f81d 300 SUPERFAMILY SSF51679 5 296 6.28E-52 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS10980 bbf09c0d3541869fe771469bb515f81d 300 TIGRFAM TIGR03619 F420_Rv2161c: probable F420-dependent oxidoreductase, Rv2161c family 28 277 5.8E-67 T 06-07-2017 IPR019921 Luciferase-like, F420-dependent oxidoreductase, Rv2161c, predicted BWK49_RS10980 bbf09c0d3541869fe771469bb515f81d 300 Pfam PF00296 Luciferase-like monooxygenase 12 213 3.0E-39 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS22400 e9259ce0d7ba21f32114b49263168f26 430 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 13 299 1.4E-75 T 06-07-2017 IPR005693 Virulence factor Mce protein BWK49_RS22400 e9259ce0d7ba21f32114b49263168f26 430 Pfam PF02470 MlaD protein 42 120 1.1E-12 T 06-07-2017 IPR003399 Mce/MlaD BWK49_RS22400 e9259ce0d7ba21f32114b49263168f26 430 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 150 430 4.8E-105 T 06-07-2017 IPR024516 Mammalian cell entry, C-terminal BWK49_RS04115 e38baa2b94c9a91a6a26d60b6570a2e5 270 Pfam PF11209 Protein of unknown function (DUF2993) 30 251 5.4E-23 T 06-07-2017 IPR021373 Protein of unknown function DUF2993 BWK49_RS27835 223ff353aafdbca4ee4c8587b51272a2 165 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 19 158 4.3E-8 T 06-07-2017 IPR019587 Polyketide cyclase/dehydrase BWK49_RS27835 223ff353aafdbca4ee4c8587b51272a2 165 Gene3D G3DSA:3.30.530.20 20 153 1.7E-9 T 06-07-2017 IPR023393 START-like domain BWK49_RS27835 223ff353aafdbca4ee4c8587b51272a2 165 SUPERFAMILY SSF55961 19 155 1.56E-13 T 06-07-2017 BWK49_RS09480 9f5915f598608d3409f96fdfcde56808 655 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 203 397 2.8E-40 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 BWK49_RS09480 9f5915f598608d3409f96fdfcde56808 655 Gene3D G3DSA:3.30.450.20 15 134 4.6E-9 T 06-07-2017 BWK49_RS09480 9f5915f598608d3409f96fdfcde56808 655 Pfam PF08448 PAS fold 21 135 1.5E-9 T 06-07-2017 IPR013656 PAS fold-4 BWK49_RS09480 9f5915f598608d3409f96fdfcde56808 655 SUPERFAMILY SSF55874 431 527 1.1E-9 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS09480 9f5915f598608d3409f96fdfcde56808 655 Gene3D G3DSA:3.30.750.24 561 638 1.1E-11 T 06-07-2017 IPR002645 STAS domain BWK49_RS09480 9f5915f598608d3409f96fdfcde56808 655 SMART SM00331 177 397 3.4E-44 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 BWK49_RS09480 9f5915f598608d3409f96fdfcde56808 655 SUPERFAMILY SSF81606 193 396 9.15E-6 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 BWK49_RS09480 9f5915f598608d3409f96fdfcde56808 655 Gene3D G3DSA:3.30.565.10 416 526 4.8E-5 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS09480 9f5915f598608d3409f96fdfcde56808 655 Pfam PF13466 STAS domain 561 631 2.6E-12 T 06-07-2017 IPR002645 STAS domain BWK49_RS09480 9f5915f598608d3409f96fdfcde56808 655 SUPERFAMILY SSF52091 561 631 8.44E-9 T 06-07-2017 IPR002645 STAS domain BWK49_RS09480 9f5915f598608d3409f96fdfcde56808 655 Pfam PF13581 Histidine kinase-like ATPase domain 410 522 6.9E-14 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS25530 a2bf5818dada5407c88b5c1ae51e6185 708 SUPERFAMILY SSF53474 447 702 3.94E-50 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS25530 a2bf5818dada5407c88b5c1ae51e6185 708 SUPERFAMILY SSF50993 18 441 1.86E-51 T 06-07-2017 BWK49_RS25530 a2bf5818dada5407c88b5c1ae51e6185 708 Pfam PF02897 Prolyl oligopeptidase, N-terminal beta-propeller domain 16 420 7.3E-25 T 06-07-2017 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 BWK49_RS25530 a2bf5818dada5407c88b5c1ae51e6185 708 Pfam PF00326 Prolyl oligopeptidase family 501 703 5.0E-48 T 06-07-2017 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 BWK49_RS25530 a2bf5818dada5407c88b5c1ae51e6185 708 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 503 527 9.4E-45 T 06-07-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 BWK49_RS25530 a2bf5818dada5407c88b5c1ae51e6185 708 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 531 550 9.4E-45 T 06-07-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 BWK49_RS25530 a2bf5818dada5407c88b5c1ae51e6185 708 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 561 581 9.4E-45 T 06-07-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 BWK49_RS25530 a2bf5818dada5407c88b5c1ae51e6185 708 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 616 631 9.4E-45 T 06-07-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 BWK49_RS25530 a2bf5818dada5407c88b5c1ae51e6185 708 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 635 657 9.4E-45 T 06-07-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 BWK49_RS25530 a2bf5818dada5407c88b5c1ae51e6185 708 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 476 494 9.4E-45 T 06-07-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 BWK49_RS25530 a2bf5818dada5407c88b5c1ae51e6185 708 Gene3D G3DSA:3.40.50.1820 395 703 1.5E-90 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS21045 0c82825d5f5463c8c60161014ba582f4 160 Gene3D G3DSA:3.30.530.20 2 157 4.0E-33 T 06-07-2017 IPR023393 START-like domain BWK49_RS21045 0c82825d5f5463c8c60161014ba582f4 160 SUPERFAMILY SSF55961 1 157 3.0E-28 T 06-07-2017 BWK49_RS21045 0c82825d5f5463c8c60161014ba582f4 160 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 10 145 3.1E-14 T 06-07-2017 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 BWK49_RS15730 b148c4d5875295e86c2eabd20cc09cf5 263 Gene3D G3DSA:3.40.50.720 8 224 2.0E-45 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS15730 b148c4d5875295e86c2eabd20cc09cf5 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 3.0E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15730 b148c4d5875295e86c2eabd20cc09cf5 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 3.0E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15730 b148c4d5875295e86c2eabd20cc09cf5 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 3.0E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15730 b148c4d5875295e86c2eabd20cc09cf5 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 3.0E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15730 b148c4d5875295e86c2eabd20cc09cf5 263 SUPERFAMILY SSF51735 8 233 2.16E-46 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS15730 b148c4d5875295e86c2eabd20cc09cf5 263 Pfam PF00106 short chain dehydrogenase 10 195 4.9E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05850 b518427245a929e925cbcf718f8f4ae1 172 Pfam PF05870 Phenolic acid decarboxylase (PAD) 14 169 6.7E-75 T 06-07-2017 IPR008729 Phenolic acid decarboxylase, bacterial GO:0016831 BWK49_RS05850 b518427245a929e925cbcf718f8f4ae1 172 SUPERFAMILY SSF50814 8 170 9.93E-69 T 06-07-2017 IPR011038 Calycin-like BWK49_RS05850 b518427245a929e925cbcf718f8f4ae1 172 ProDom PD022010 DECARBOXYLASE ACID PHENOLIC P-COUMARIC LYASE 4.1.1.- PAD PADC FERULATE PROBABLE 17 160 9.0E-79 T 06-07-2017 IPR008729 Phenolic acid decarboxylase, bacterial GO:0016831 BWK49_RS05850 b518427245a929e925cbcf718f8f4ae1 172 Gene3D G3DSA:2.40.128.20 13 171 3.5E-69 T 06-07-2017 IPR012674 Calycin BWK49_RS21530 cef2afa6810dfe5a77c026bd4c705c91 280 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 6 272 4.9E-56 T 06-07-2017 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 BWK49_RS21530 cef2afa6810dfe5a77c026bd4c705c91 280 SUPERFAMILY SSF51197 4 279 5.95E-70 T 06-07-2017 BWK49_RS21530 cef2afa6810dfe5a77c026bd4c705c91 280 Gene3D G3DSA:3.60.130.10 4 279 4.1E-69 T 06-07-2017 BWK49_RS16710 a2029fc0cb20797e7a6c4398bbc9793c 239 TIGRFAM TIGR00025 Mtu_efflux: ABC transporter efflux protein, DrrB family 15 238 8.0E-77 T 06-07-2017 IPR004377 ABC transporter, permease protein DrrB/DrrC GO:0042891|GO:0043215|GO:0046677|GO:1900753 BWK49_RS16710 a2029fc0cb20797e7a6c4398bbc9793c 239 Pfam PF01061 ABC-2 type transporter 12 201 1.8E-32 T 06-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 BWK49_RS16710 a2029fc0cb20797e7a6c4398bbc9793c 239 PIRSF PIRSF006648 1 239 1.3E-18 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 BWK49_RS13830 6320bee0e4221b3db5c4e917ee90f9a5 206 Pfam PF08281 Sigma-70, region 4 146 194 1.5E-9 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS13830 6320bee0e4221b3db5c4e917ee90f9a5 206 Pfam PF04542 Sigma-70 region 2 26 93 4.6E-16 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS13830 6320bee0e4221b3db5c4e917ee90f9a5 206 Gene3D G3DSA:1.10.10.10 139 202 1.5E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS13830 6320bee0e4221b3db5c4e917ee90f9a5 206 SUPERFAMILY SSF88659 133 201 1.78E-12 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS13830 6320bee0e4221b3db5c4e917ee90f9a5 206 Gene3D G3DSA:1.10.1740.10 24 105 5.2E-20 T 06-07-2017 BWK49_RS13830 6320bee0e4221b3db5c4e917ee90f9a5 206 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 24 200 6.6E-25 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS13830 6320bee0e4221b3db5c4e917ee90f9a5 206 SUPERFAMILY SSF88946 24 102 1.1E-18 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS22560 26a111aa604d39c8dcaf8effe92b045e 161 Gene3D G3DSA:2.60.120.10 26 150 1.1E-25 T 06-07-2017 IPR014710 RmlC-like jelly roll fold BWK49_RS22560 26a111aa604d39c8dcaf8effe92b045e 161 Pfam PF07883 Cupin domain 33 99 9.6E-12 T 06-07-2017 IPR013096 Cupin 2, conserved barrel BWK49_RS22560 26a111aa604d39c8dcaf8effe92b045e 161 SUPERFAMILY SSF51182 15 112 1.37E-20 T 06-07-2017 IPR011051 RmlC-like cupin domain BWK49_RS09280 b1cbb09a6fa95284ab4029e7a21c1bd9 338 Gene3D G3DSA:3.20.20.70 15 335 1.9E-49 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 BWK49_RS09280 b1cbb09a6fa95284ab4029e7a21c1bd9 338 SMART SM01130 14 331 6.0E-27 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 BWK49_RS09280 b1cbb09a6fa95284ab4029e7a21c1bd9 338 SUPERFAMILY SSF51569 15 332 7.33E-36 T 06-07-2017 BWK49_RS09280 b1cbb09a6fa95284ab4029e7a21c1bd9 338 Pfam PF00701 Dihydrodipicolinate synthetase family 16 205 8.7E-14 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 BWK49_RS11330 aaf912af3931df4042fffa9c98391b2e 543 Pfam PF00258 Flavodoxin 11 136 1.6E-27 T 06-07-2017 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 BWK49_RS11330 aaf912af3931df4042fffa9c98391b2e 543 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 435 446 1.5E-28 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 BWK49_RS11330 aaf912af3931df4042fffa9c98391b2e 543 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 492 500 1.5E-28 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 BWK49_RS11330 aaf912af3931df4042fffa9c98391b2e 543 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 331 338 1.5E-28 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 BWK49_RS11330 aaf912af3931df4042fffa9c98391b2e 543 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 469 485 1.5E-28 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 BWK49_RS11330 aaf912af3931df4042fffa9c98391b2e 543 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 217 227 1.5E-28 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 BWK49_RS11330 aaf912af3931df4042fffa9c98391b2e 543 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 422 431 1.5E-28 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 BWK49_RS11330 aaf912af3931df4042fffa9c98391b2e 543 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 364 373 1.5E-28 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 BWK49_RS11330 aaf912af3931df4042fffa9c98391b2e 543 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 397 416 1.5E-28 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 BWK49_RS11330 aaf912af3931df4042fffa9c98391b2e 543 Gene3D G3DSA:1.20.990.10 228 328 3.0E-10 T 06-07-2017 IPR023173 NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain-3 GO:0016491|GO:0055114 BWK49_RS11330 aaf912af3931df4042fffa9c98391b2e 543 Gene3D G3DSA:3.40.50.80 399 542 2.2E-56 T 06-07-2017 BWK49_RS11330 aaf912af3931df4042fffa9c98391b2e 543 Gene3D G3DSA:3.40.50.360 6 152 1.3E-38 T 06-07-2017 IPR029039 Flavoprotein-like domain BWK49_RS11330 aaf912af3931df4042fffa9c98391b2e 543 SUPERFAMILY SSF52343 386 543 3.14E-50 T 06-07-2017 BWK49_RS11330 aaf912af3931df4042fffa9c98391b2e 543 Pfam PF00175 Oxidoreductase NAD-binding domain 398 507 4.0E-21 T 06-07-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 BWK49_RS11330 aaf912af3931df4042fffa9c98391b2e 543 SUPERFAMILY SSF52218 8 152 1.8E-40 T 06-07-2017 IPR029039 Flavoprotein-like domain BWK49_RS11330 aaf912af3931df4042fffa9c98391b2e 543 PRINTS PR00369 Flavodoxin signature 91 101 8.2E-11 T 06-07-2017 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 BWK49_RS11330 aaf912af3931df4042fffa9c98391b2e 543 PRINTS PR00369 Flavodoxin signature 115 134 8.2E-11 T 06-07-2017 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 BWK49_RS11330 aaf912af3931df4042fffa9c98391b2e 543 PRINTS PR00369 Flavodoxin signature 10 23 8.2E-11 T 06-07-2017 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 BWK49_RS11330 aaf912af3931df4042fffa9c98391b2e 543 PRINTS PR00369 Flavodoxin signature 59 70 8.2E-11 T 06-07-2017 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 BWK49_RS11330 aaf912af3931df4042fffa9c98391b2e 543 SUPERFAMILY SSF63380 178 388 6.5E-50 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 BWK49_RS11330 aaf912af3931df4042fffa9c98391b2e 543 Pfam PF00667 FAD binding domain 178 246 7.1E-13 T 06-07-2017 IPR003097 FAD-binding, type 1 GO:0016491|GO:0055114 BWK49_RS11330 aaf912af3931df4042fffa9c98391b2e 543 Pfam PF00667 FAD binding domain 306 369 5.1E-11 T 06-07-2017 IPR003097 FAD-binding, type 1 GO:0016491|GO:0055114 BWK49_RS11330 aaf912af3931df4042fffa9c98391b2e 543 Gene3D G3DSA:2.40.30.10 180 227 1.6E-32 T 06-07-2017 BWK49_RS11330 aaf912af3931df4042fffa9c98391b2e 543 Gene3D G3DSA:2.40.30.10 329 398 1.6E-32 T 06-07-2017 BWK49_RS07120 c7d1657f868f60f5247b89da9ef00d0a 303 Pfam PF00483 Nucleotidyl transferase 12 277 2.1E-26 T 06-07-2017 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 BWK49_RS07120 c7d1657f868f60f5247b89da9ef00d0a 303 SUPERFAMILY SSF53448 11 292 9.01E-53 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases BWK49_RS07120 c7d1657f868f60f5247b89da9ef00d0a 303 Gene3D G3DSA:3.90.550.10 10 282 1.3E-56 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases BWK49_RS07955 4c5550e28c29aa6fff1f03f85fe2c92d 227 Gene3D G3DSA:2.30.30.330 8 134 4.3E-51 T 06-07-2017 BWK49_RS07955 4c5550e28c29aa6fff1f03f85fe2c92d 227 Gene3D G3DSA:2.30.30.330 174 221 4.3E-51 T 06-07-2017 BWK49_RS07955 4c5550e28c29aa6fff1f03f85fe2c92d 227 SUPERFAMILY SSF54001 169 212 1.37E-23 T 06-07-2017 BWK49_RS07955 4c5550e28c29aa6fff1f03f85fe2c92d 227 SUPERFAMILY SSF54001 10 129 1.37E-23 T 06-07-2017 BWK49_RS25950 58020b87020603e599349b2206631333 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 1.1E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS25950 58020b87020603e599349b2206631333 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 1.1E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS25950 58020b87020603e599349b2206631333 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 1.1E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS25950 58020b87020603e599349b2206631333 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.1E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS25950 58020b87020603e599349b2206631333 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 1.1E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS25950 58020b87020603e599349b2206631333 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.1E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS25950 58020b87020603e599349b2206631333 248 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS25950 58020b87020603e599349b2206631333 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 2.0E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS25950 58020b87020603e599349b2206631333 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 2.0E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS25950 58020b87020603e599349b2206631333 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 2.0E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS25950 58020b87020603e599349b2206631333 248 Gene3D G3DSA:3.40.50.720 9 246 1.4E-80 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS25950 58020b87020603e599349b2206631333 248 SUPERFAMILY SSF51735 10 246 4.0E-76 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS25950 58020b87020603e599349b2206631333 248 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 245 1.1E-60 T 06-07-2017 BWK49_RS01845 0099b1d065fc92e54604bab462a88f2b 77 Pfam PF13187 4Fe-4S dicluster domain 10 64 2.8E-8 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain BWK49_RS01845 0099b1d065fc92e54604bab462a88f2b 77 SUPERFAMILY SSF54862 4 69 6.62E-14 T 06-07-2017 BWK49_RS01845 0099b1d065fc92e54604bab462a88f2b 77 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 10 21 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site BWK49_RS01845 0099b1d065fc92e54604bab462a88f2b 77 Gene3D G3DSA:3.30.70.20 4 66 6.4E-12 T 06-07-2017 BWK49_RS18500 3074ba635fe3ab5a4958ccb25c5b7c1d 384 Pfam PF00144 Beta-lactamase 3 354 4.4E-66 T 06-07-2017 IPR001466 Beta-lactamase-related BWK49_RS18500 3074ba635fe3ab5a4958ccb25c5b7c1d 384 SUPERFAMILY SSF56601 3 351 1.26E-81 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like BWK49_RS18500 3074ba635fe3ab5a4958ccb25c5b7c1d 384 Gene3D G3DSA:3.40.710.10 3 349 1.1E-75 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like BWK49_RS20815 bb72221dff5b692cb60f167ee0b744e5 309 SMART SM00829 10 305 1.2E-18 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 BWK49_RS20815 bb72221dff5b692cb60f167ee0b744e5 309 Gene3D G3DSA:3.40.50.720 150 240 1.9E-20 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS20815 bb72221dff5b692cb60f167ee0b744e5 309 SUPERFAMILY SSF51735 116 275 3.13E-33 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS20815 bb72221dff5b692cb60f167ee0b744e5 309 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 87 3.9E-5 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 BWK49_RS20815 bb72221dff5b692cb60f167ee0b744e5 309 SUPERFAMILY SSF50129 1 149 6.45E-29 T 06-07-2017 IPR011032 GroES-like BWK49_RS20815 bb72221dff5b692cb60f167ee0b744e5 309 Pfam PF13602 Zinc-binding dehydrogenase 187 305 6.6E-25 T 06-07-2017 BWK49_RS20815 bb72221dff5b692cb60f167ee0b744e5 309 Gene3D G3DSA:3.90.180.10 1 149 5.2E-35 T 06-07-2017 IPR011032 GroES-like BWK49_RS07285 63152b8f52d802909679caf6a005910e 545 SUPERFAMILY SSF51445 236 377 1.93E-7 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily BWK49_RS07285 63152b8f52d802909679caf6a005910e 545 SUPERFAMILY SSF51445 72 202 1.93E-7 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily BWK49_RS07285 63152b8f52d802909679caf6a005910e 545 Gene3D G3DSA:3.20.20.80 91 267 3.8E-6 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 BWK49_RS16650 6db10ae146ddf0bdc84249bd23030c35 393 Pfam PF12555 Thiamine pyrophosphokinase C terminal 334 384 2.6E-16 T 06-07-2017 IPR022215 Thiamine pyrophosphokinase C-terminal BWK49_RS16650 6db10ae146ddf0bdc84249bd23030c35 393 SUPERFAMILY SSF63999 179 301 2.09E-13 T 06-07-2017 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 BWK49_RS08415 43e5e23aefb9c0a319ab83b82c4d2406 302 Gene3D G3DSA:3.40.50.1820 15 299 1.2E-38 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS08415 43e5e23aefb9c0a319ab83b82c4d2406 302 SUPERFAMILY SSF53474 14 296 3.41E-36 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS08415 43e5e23aefb9c0a319ab83b82c4d2406 302 Pfam PF00561 alpha/beta hydrolase fold 35 134 2.9E-9 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS03215 5e0c68fa03929706f766f27990731527 236 Pfam PF14032 PknH-like extracellular domain 43 232 2.8E-43 T 06-07-2017 IPR026954 PknH-like extracellular domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 BWK49_RS07300 1be4d36d6fb4db988399cd385e3e8249 337 SUPERFAMILY SSF53756 39 329 1.62E-49 T 06-07-2017 BWK49_RS07300 1be4d36d6fb4db988399cd385e3e8249 337 Gene3D G3DSA:3.40.50.2000 163 307 2.0E-11 T 06-07-2017 BWK49_RS07300 1be4d36d6fb4db988399cd385e3e8249 337 Pfam PF13439 Glycosyltransferase Family 4 40 156 1.1E-7 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 BWK49_RS07300 1be4d36d6fb4db988399cd385e3e8249 337 Pfam PF13692 Glycosyl transferases group 1 166 297 2.1E-18 T 06-07-2017 BWK49_RS02215 575ace32aa4fbfd48b9582103d5cb472 121 Pfam PF00188 Cysteine-rich secretory protein family 9 118 1.8E-12 T 06-07-2017 IPR014044 CAP domain BWK49_RS02215 575ace32aa4fbfd48b9582103d5cb472 121 SUPERFAMILY SSF55797 5 115 7.06E-15 T 06-07-2017 IPR014044 CAP domain BWK49_RS02215 575ace32aa4fbfd48b9582103d5cb472 121 Gene3D G3DSA:3.40.33.10 6 85 2.5E-5 T 06-07-2017 IPR014044 CAP domain BWK49_RS14050 0faedff8811e5a4047a2a1028766e988 202 Pfam PF08310 LGFP repeat 86 136 1.5E-5 T 06-07-2017 IPR013207 LGFP BWK49_RS06180 c05473c7b95322a53d44f270a048251d 318 SUPERFAMILY SSF51679 19 305 1.18E-48 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS06180 c05473c7b95322a53d44f270a048251d 318 TIGRFAM TIGR03564 F420_MSMEG_4879: F420-dependent oxidoreductase, MSMEG_4879 family 23 287 1.6E-100 T 06-07-2017 IPR019910 Luciferase-like, F420-dependent oxidoreductase, MSMEG4879, predicted BWK49_RS06180 c05473c7b95322a53d44f270a048251d 318 Gene3D G3DSA:3.20.20.30 2 309 3.3E-46 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS06180 c05473c7b95322a53d44f270a048251d 318 Pfam PF00296 Luciferase-like monooxygenase 18 284 1.1E-44 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS24105 fdd70ae37f84ff35eeb73bf9cacef3d2 506 Pfam PF00171 Aldehyde dehydrogenase family 17 486 3.4E-142 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 BWK49_RS24105 fdd70ae37f84ff35eeb73bf9cacef3d2 506 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 6 490 1.3E-192 T 06-07-2017 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00410+1.2.1.18|KEGG: 00562+1.2.1.18|KEGG: 00640+1.2.1.18+1.2.1.27|MetaCyc: PWY-5642|MetaCyc: PWY-6373|Reactome: R-HSA-70895 BWK49_RS24105 fdd70ae37f84ff35eeb73bf9cacef3d2 506 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 275 286 - T 06-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 BWK49_RS24105 fdd70ae37f84ff35eeb73bf9cacef3d2 506 SUPERFAMILY SSF53720 2 490 5.37E-156 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 BWK49_RS24105 fdd70ae37f84ff35eeb73bf9cacef3d2 506 Gene3D G3DSA:3.40.605.10 3 260 3.5E-93 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 BWK49_RS24105 fdd70ae37f84ff35eeb73bf9cacef3d2 506 Gene3D G3DSA:3.40.309.10 261 459 8.1E-64 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 BWK49_RS04305 0a21906855203571c44effd773b61426 335 Pfam PF10774 Domain of unknown function (DUF4226) 56 159 1.3E-6 T 06-07-2017 IPR019710 Protein of unknown function DUF4226 BWK49_RS16580 cd63d8f44b5ca1dbcf2ea2a48aad7101 69 Gene3D G3DSA:1.10.10.10 11 64 5.8E-8 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS16580 cd63d8f44b5ca1dbcf2ea2a48aad7101 69 Pfam PF12728 Helix-turn-helix domain 8 61 4.4E-9 T 06-07-2017 BWK49_RS16580 cd63d8f44b5ca1dbcf2ea2a48aad7101 69 SUPERFAMILY SSF46955 8 62 5.49E-9 T 06-07-2017 IPR009061 Putative DNA-binding domain BWK49_RS03665 2508172361ac18ae000bf06e90b6c00e 279 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 146 174 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS03665 2508172361ac18ae000bf06e90b6c00e 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 2.6E-27 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS03665 2508172361ac18ae000bf06e90b6c00e 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 2.6E-27 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS03665 2508172361ac18ae000bf06e90b6c00e 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 2.6E-27 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS03665 2508172361ac18ae000bf06e90b6c00e 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 2.6E-27 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS03665 2508172361ac18ae000bf06e90b6c00e 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 2.6E-27 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS03665 2508172361ac18ae000bf06e90b6c00e 279 Gene3D G3DSA:3.40.50.720 4 257 2.8E-76 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS03665 2508172361ac18ae000bf06e90b6c00e 279 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 251 1.1E-54 T 06-07-2017 BWK49_RS03665 2508172361ac18ae000bf06e90b6c00e 279 SUPERFAMILY SSF51735 4 255 3.9E-72 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS03665 2508172361ac18ae000bf06e90b6c00e 279 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 195 0.0039 T 06-07-2017 BWK49_RS23445 61a76d5f627aa1a3c685af655264bc10 209 SUPERFAMILY SSF69118 4 178 6.88E-43 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 BWK49_RS23445 61a76d5f627aa1a3c685af655264bc10 209 Pfam PF02627 Carboxymuconolactone decarboxylase family 51 127 9.7E-6 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 BWK49_RS23445 61a76d5f627aa1a3c685af655264bc10 209 Gene3D G3DSA:1.20.1290.10 34 180 4.4E-38 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 BWK49_RS18365 6ce4c7afa0c23ee99740504d290d2bca 518 SUPERFAMILY SSF103473 6 200 5.1E-48 T 06-07-2017 IPR020846 Major facilitator superfamily domain BWK49_RS18365 6ce4c7afa0c23ee99740504d290d2bca 518 SUPERFAMILY SSF103473 254 435 5.1E-48 T 06-07-2017 IPR020846 Major facilitator superfamily domain BWK49_RS18365 6ce4c7afa0c23ee99740504d290d2bca 518 SUPERFAMILY SSF103473 472 508 5.1E-48 T 06-07-2017 IPR020846 Major facilitator superfamily domain BWK49_RS18365 6ce4c7afa0c23ee99740504d290d2bca 518 ProSitePatterns PS00216 Sugar transport proteins signature 1. 67 83 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 BWK49_RS18365 6ce4c7afa0c23ee99740504d290d2bca 518 Pfam PF07690 Major Facilitator Superfamily 16 426 9.5E-41 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 BWK49_RS18365 6ce4c7afa0c23ee99740504d290d2bca 518 Gene3D G3DSA:1.20.1250.20 271 443 4.5E-9 T 06-07-2017 BWK49_RS18365 6ce4c7afa0c23ee99740504d290d2bca 518 Gene3D G3DSA:1.20.1250.20 477 506 4.5E-9 T 06-07-2017 BWK49_RS18365 6ce4c7afa0c23ee99740504d290d2bca 518 Gene3D G3DSA:1.20.1250.20 14 201 1.7E-29 T 06-07-2017 BWK49_RS17375 ef0e1af8fb5e3dd3858ebd75a39b0c3f 75 ProDom PD028237 MB1616 ML1221 CGL0073 RV1590/MT1625 14 74 1.0E-27 T 06-07-2017 BWK49_RS18700 dffd31a02f2c60f852ef1ed380ce5730 165 Gene3D G3DSA:3.30.530.20 18 155 1.3E-21 T 06-07-2017 IPR023393 START-like domain BWK49_RS18700 dffd31a02f2c60f852ef1ed380ce5730 165 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 19 154 5.5E-21 T 06-07-2017 IPR019587 Polyketide cyclase/dehydrase BWK49_RS18700 dffd31a02f2c60f852ef1ed380ce5730 165 SUPERFAMILY SSF55961 19 156 3.5E-22 T 06-07-2017 BWK49_RS05625 6b837416b7f04064917717d785b3913a 90 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 3 41 3.3E-7 T 06-07-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM BWK49_RS26715 1c5fdc8d3038c509454cd941a22d2444 283 PRINTS PR01483 Fatty acid synthase signature 203 224 4.9E-9 T 06-07-2017 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 BWK49_RS26715 1c5fdc8d3038c509454cd941a22d2444 283 PRINTS PR01483 Fatty acid synthase signature 181 203 4.9E-9 T 06-07-2017 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 BWK49_RS26715 1c5fdc8d3038c509454cd941a22d2444 283 SUPERFAMILY SSF54637 38 163 1.37E-9 T 06-07-2017 IPR029069 HotDog domain BWK49_RS26715 1c5fdc8d3038c509454cd941a22d2444 283 Gene3D G3DSA:3.10.129.10 52 149 8.6E-5 T 06-07-2017 IPR029069 HotDog domain BWK49_RS26715 1c5fdc8d3038c509454cd941a22d2444 283 Pfam PF01575 MaoC like domain 166 255 5.5E-21 T 06-07-2017 IPR002539 MaoC-like domain BWK49_RS26715 1c5fdc8d3038c509454cd941a22d2444 283 SUPERFAMILY SSF54637 168 280 6.84E-21 T 06-07-2017 IPR029069 HotDog domain BWK49_RS26715 1c5fdc8d3038c509454cd941a22d2444 283 Gene3D G3DSA:3.10.129.10 174 280 2.3E-23 T 06-07-2017 IPR029069 HotDog domain BWK49_RS21030 68b9e020d8bcbdb18622c1aed2bd9c0d 368 Gene3D G3DSA:3.90.1150.10 245 365 8.9E-28 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 BWK49_RS21030 68b9e020d8bcbdb18622c1aed2bd9c0d 368 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 44 364 8.8E-80 T 06-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 BWK49_RS21030 68b9e020d8bcbdb18622c1aed2bd9c0d 368 SUPERFAMILY SSF53383 40 364 5.3E-79 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase BWK49_RS21030 68b9e020d8bcbdb18622c1aed2bd9c0d 368 Gene3D G3DSA:3.40.640.10 8 243 1.3E-62 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 BWK49_RS21030 68b9e020d8bcbdb18622c1aed2bd9c0d 368 PIRSF PIRSF001434 4 368 3.4E-99 T 06-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 BWK49_RS01475 f0fddd0b9b9cf2f1e1598f433f22068d 67 SUPERFAMILY SSF53098 3 41 5.01E-6 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS01475 f0fddd0b9b9cf2f1e1598f433f22068d 67 Gene3D G3DSA:3.30.420.10 2 30 2.8E-5 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS24985 aa5b7a2a94ce53f60cbab66a42f68253 384 Pfam PF00534 Glycosyl transferases group 1 199 336 1.4E-21 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 BWK49_RS24985 aa5b7a2a94ce53f60cbab66a42f68253 384 Gene3D G3DSA:3.40.50.2000 21 143 6.1E-4 T 06-07-2017 BWK49_RS24985 aa5b7a2a94ce53f60cbab66a42f68253 384 Gene3D G3DSA:3.40.50.2000 172 341 4.4E-20 T 06-07-2017 BWK49_RS24985 aa5b7a2a94ce53f60cbab66a42f68253 384 Pfam PF13439 Glycosyltransferase Family 4 14 182 7.0E-23 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 BWK49_RS24985 aa5b7a2a94ce53f60cbab66a42f68253 384 SUPERFAMILY SSF53756 2 367 1.6E-66 T 06-07-2017 BWK49_RS18360 8f46277ebeebd6f78ed19446a0077835 235 Pfam PF07161 Protein of unknown function (DUF1396) 37 228 1.2E-78 T 06-07-2017 IPR009830 LppX/LprAFG lipoprotein family BWK49_RS18360 8f46277ebeebd6f78ed19446a0077835 235 SUPERFAMILY SSF89392 34 229 1.53E-59 T 06-07-2017 IPR029046 Lipoprotein localisation LolA/LolB/LppX BWK49_RS18360 8f46277ebeebd6f78ed19446a0077835 235 ProDom PD017293 LIPOPROTEIN MEMBRANE PRECURSOR PALMITATE SIGNAL ANTIGEN LPRG LPPX P27 LPRA 23 228 2.0E-102 T 06-07-2017 IPR009830 LppX/LprAFG lipoprotein family BWK49_RS14630 6a988fed9501e6943b5d39eec4c014fa 320 Gene3D G3DSA:3.40.50.720 261 317 1.4E-55 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS14630 6a988fed9501e6943b5d39eec4c014fa 320 Gene3D G3DSA:3.40.50.720 135 188 1.4E-55 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS14630 6a988fed9501e6943b5d39eec4c014fa 320 Gene3D G3DSA:3.40.50.720 4 71 1.4E-55 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS14630 6a988fed9501e6943b5d39eec4c014fa 320 SUPERFAMILY SSF51971 263 317 2.59E-30 T 06-07-2017 BWK49_RS14630 6a988fed9501e6943b5d39eec4c014fa 320 SUPERFAMILY SSF51971 4 202 2.59E-30 T 06-07-2017 BWK49_RS14630 6a988fed9501e6943b5d39eec4c014fa 320 Pfam PF01266 FAD dependent oxidoreductase 7 315 1.1E-37 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 BWK49_RS14630 6a988fed9501e6943b5d39eec4c014fa 320 SUPERFAMILY SSF54373 189 278 2.09E-17 T 06-07-2017 BWK49_RS14630 6a988fed9501e6943b5d39eec4c014fa 320 PIRSF PIRSF000189 3 320 6.2E-73 T 06-07-2017 IPR023209 D-amino-acid oxidase GO:0003884|GO:0046416|GO:0071949 Reactome: R-HSA-389661 BWK49_RS19420 d3d70f1880bb10ca0deed4e82963431b 269 Gene3D G3DSA:3.30.420.40 20 126 1.8E-40 T 06-07-2017 BWK49_RS19420 d3d70f1880bb10ca0deed4e82963431b 269 Pfam PF00480 ROK family 26 180 3.9E-14 T 06-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 BWK49_RS19420 d3d70f1880bb10ca0deed4e82963431b 269 SUPERFAMILY SSF53067 25 264 5.28E-30 T 06-07-2017 BWK49_RS19420 d3d70f1880bb10ca0deed4e82963431b 269 Gene3D G3DSA:3.30.420.40 127 266 1.1E-32 T 06-07-2017 BWK49_RS25700 7c11c0ee079266775c0103fca49670a7 272 SUPERFAMILY SSF52096 1 260 2.96E-69 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS25700 7c11c0ee079266775c0103fca49670a7 272 Gene3D G3DSA:3.90.226.10 3 198 2.7E-57 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS25700 7c11c0ee079266775c0103fca49670a7 272 Pfam PF00378 Enoyl-CoA hydratase/isomerase 8 260 3.9E-49 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 BWK49_RS25700 7c11c0ee079266775c0103fca49670a7 272 Gene3D G3DSA:1.10.12.10 202 261 8.2E-15 T 06-07-2017 IPR014748 Crontonase, C-terminal BWK49_RS23255 e27e00e638ddded2519ad5a39cca161f 219 Gene3D G3DSA:1.10.357.10 11 200 5.1E-31 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS23255 e27e00e638ddded2519ad5a39cca161f 219 SUPERFAMILY SSF46689 2 74 6.8E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS23255 e27e00e638ddded2519ad5a39cca161f 219 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 5.0E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS23255 e27e00e638ddded2519ad5a39cca161f 219 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 5.0E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS23255 e27e00e638ddded2519ad5a39cca161f 219 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 63 3.6E-15 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS18955 1b328954478d51a570d3205d7834a6c4 234 Gene3D G3DSA:1.10.10.10 7 90 2.9E-7 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS18955 1b328954478d51a570d3205d7834a6c4 234 Pfam PF12840 Helix-turn-helix domain 16 67 8.7E-7 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS18955 1b328954478d51a570d3205d7834a6c4 234 SUPERFAMILY SSF46785 14 209 1.26E-9 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS18180 3ea3334dd410de0dd28b597c3c4d2160 258 TIGRFAM TIGR00025 Mtu_efflux: ABC transporter efflux protein, DrrB family 35 258 4.7E-70 T 06-07-2017 IPR004377 ABC transporter, permease protein DrrB/DrrC GO:0042891|GO:0043215|GO:0046677|GO:1900753 BWK49_RS18180 3ea3334dd410de0dd28b597c3c4d2160 258 PIRSF PIRSF006648 6 256 2.8E-17 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 BWK49_RS18180 3ea3334dd410de0dd28b597c3c4d2160 258 Pfam PF01061 ABC-2 type transporter 31 228 5.0E-12 T 06-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 BWK49_RS08125 23f1189d90b28b21b10c6eec923aba32 166 Pfam PF04140 Isoprenylcysteine carboxyl methyltransferase (ICMT) family 74 163 1.5E-26 T 06-07-2017 IPR007269 Isoprenylcysteine carboxyl methyltransferase GO:0004671|GO:0006481|GO:0016021 Reactome: R-HSA-163841 BWK49_RS23580 6c4e39fd04f394cac0a1753f348c5b99 127 Gene3D G3DSA:1.10.10.10 57 100 7.8E-4 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS23580 6c4e39fd04f394cac0a1753f348c5b99 127 Pfam PF05331 Protein of unknown function (DUF742) 11 127 5.3E-31 T 06-07-2017 IPR007995 Protein of unknown function DUF742 BWK49_RS12755 0183ec6768dcf7d121cb013368a42542 478 ProSitePatterns PS00180 Glutamine synthetase signature 1. 53 71 - T 06-07-2017 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 BWK49_RS12755 0183ec6768dcf7d121cb013368a42542 478 SMART SM01230 105 387 1.8E-146 T 06-07-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 BWK49_RS12755 0183ec6768dcf7d121cb013368a42542 478 Gene3D G3DSA:3.30.590.10 109 457 1.2E-134 T 06-07-2017 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 BWK49_RS12755 0183ec6768dcf7d121cb013368a42542 478 Gene3D G3DSA:3.10.20.70 5 108 3.1E-37 T 06-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 BWK49_RS12755 0183ec6768dcf7d121cb013368a42542 478 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 265 280 - T 06-07-2017 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 BWK49_RS12755 0183ec6768dcf7d121cb013368a42542 478 SUPERFAMILY SSF54368 5 103 4.45E-33 T 06-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 BWK49_RS12755 0183ec6768dcf7d121cb013368a42542 478 ProSitePatterns PS00182 Glutamine synthetase class-I adenylation site. 394 406 - T 06-07-2017 IPR001637 Glutamine synthetase class-I, adenylation site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 BWK49_RS12755 0183ec6768dcf7d121cb013368a42542 478 Pfam PF00120 Glutamine synthetase, catalytic domain 106 475 3.5E-134 T 06-07-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 BWK49_RS12755 0183ec6768dcf7d121cb013368a42542 478 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 8 477 5.7E-206 T 06-07-2017 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 BWK49_RS12755 0183ec6768dcf7d121cb013368a42542 478 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 17 98 3.3E-26 T 06-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 BWK49_RS12755 0183ec6768dcf7d121cb013368a42542 478 SUPERFAMILY SSF55931 106 477 6.38E-138 T 06-07-2017 BWK49_RS22995 d216dcd6c677e664cc6808d2fdb302fe 140 SUPERFAMILY SSF55486 13 135 6.23E-20 T 06-07-2017 BWK49_RS22995 d216dcd6c677e664cc6808d2fdb302fe 140 Pfam PF06262 Zinicin-like metallopeptidase 71 130 4.2E-5 T 06-07-2017 IPR010428 Zinicin-like metallopeptidase BWK49_RS14955 0a4af5009a495425c2943fc56abc233b 220 Pfam PF10708 Protein of unknown function (DUF2510) 14 47 6.0E-9 T 06-07-2017 IPR018929 Domain of unknown function DUF2510 BWK49_RS07880 fcfe47d64522441c672a6f5bcf2c684f 332 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 25 304 2.9E-98 T 06-07-2017 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 BWK49_RS07880 fcfe47d64522441c672a6f5bcf2c684f 332 Pfam PF02401 LytB protein 25 302 5.5E-90 T 06-07-2017 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 BWK49_RS07880 fcfe47d64522441c672a6f5bcf2c684f 332 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 23 306 36.84 T 06-07-2017 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 BWK49_RS24725 410fd34fb18b8db83674d9fea38526e5 881 TIGRFAM TIGR01180 aman2_put: putative alpha-1,2-mannosidase 37 752 8.9E-145 T 06-07-2017 IPR005887 Alpha-1,2-mannosidase, putative BWK49_RS24725 410fd34fb18b8db83674d9fea38526e5 881 Gene3D G3DSA:3.30.2080.10 613 761 2.5E-47 T 06-07-2017 BWK49_RS24725 410fd34fb18b8db83674d9fea38526e5 881 SUPERFAMILY SSF48208 283 702 2.49E-21 T 06-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 BWK49_RS24725 410fd34fb18b8db83674d9fea38526e5 881 Gene3D G3DSA:2.70.98.10 38 339 2.3E-88 T 06-07-2017 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0003824|GO:0005975|GO:0030246 BWK49_RS24725 410fd34fb18b8db83674d9fea38526e5 881 Pfam PF07971 Glycosyl hydrolase family 92 259 749 2.5E-137 T 06-07-2017 IPR012939 Glycosyl hydrolase family 92 BWK49_RS24725 410fd34fb18b8db83674d9fea38526e5 881 Gene3D G3DSA:1.20.1610.10 461 612 1.8E-38 T 06-07-2017 BWK49_RS24725 410fd34fb18b8db83674d9fea38526e5 881 Gene3D G3DSA:1.20.1050.60 364 452 8.6E-25 T 06-07-2017 BWK49_RS01025 a9b6d1788dadb3c2f70dc8a3862f61bc 314 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 76 221 1.0E-37 T 06-07-2017 IPR004474 Cell envelope-related transcriptional attenuator domain BWK49_RS01025 a9b6d1788dadb3c2f70dc8a3862f61bc 314 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 77 220 1.6E-42 T 06-07-2017 IPR004474 Cell envelope-related transcriptional attenuator domain BWK49_RS11015 7b8342316c700818dca992c958f21e01 394 Pfam PF04909 Amidohydrolase 100 387 3.2E-27 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 BWK49_RS11015 7b8342316c700818dca992c958f21e01 394 SUPERFAMILY SSF51556 92 393 5.76E-65 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS11015 7b8342316c700818dca992c958f21e01 394 SUPERFAMILY SSF51556 11 38 5.76E-65 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS11015 7b8342316c700818dca992c958f21e01 394 Gene3D G3DSA:3.20.20.140 22 393 1.4E-57 T 06-07-2017 BWK49_RS00095 417d8529e1a67057fd36b6d474cc1225 247 Pfam PF05949 Bacterial protein of unknown function (DUF881) 90 240 2.5E-36 T 06-07-2017 IPR010273 Protein of unknown function DUF881 BWK49_RS17090 bed8c30cf7bf40f44c2abd4b7bf0b613 527 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 86 225 6.3E-8 T 06-07-2017 BWK49_RS22970 2a47cde4063899a2483292e45417fc47 491 Gene3D G3DSA:3.50.50.60 315 348 1.7E-15 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS22970 2a47cde4063899a2483292e45417fc47 491 Gene3D G3DSA:3.50.50.60 13 204 1.7E-15 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS22970 2a47cde4063899a2483292e45417fc47 491 SUPERFAMILY SSF51905 304 401 1.64E-25 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS22970 2a47cde4063899a2483292e45417fc47 491 SUPERFAMILY SSF51905 11 197 1.64E-25 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS20240 35016b92eb3b59004166f8fd23df97e8 124 TIGRFAM TIGR00252 TIGR00252: TIGR00252 family protein 10 108 2.1E-21 T 06-07-2017 IPR003509 Uncharacterised protein family UPF0102 BWK49_RS20240 35016b92eb3b59004166f8fd23df97e8 124 Hamap MF_00048 UPF0102 protein YraN [yraN]. 9 120 22.761 T 06-07-2017 IPR003509 Uncharacterised protein family UPF0102 BWK49_RS20240 35016b92eb3b59004166f8fd23df97e8 124 Gene3D G3DSA:3.40.1350.10 15 123 9.9E-35 T 06-07-2017 IPR011856 tRNA endonuclease-like domain GO:0003676|GO:0004518 Reactome: R-HSA-6784531 BWK49_RS20240 35016b92eb3b59004166f8fd23df97e8 124 Pfam PF02021 Uncharacterised protein family UPF0102 16 107 9.6E-29 T 06-07-2017 IPR003509 Uncharacterised protein family UPF0102 BWK49_RS20240 35016b92eb3b59004166f8fd23df97e8 124 SUPERFAMILY SSF52980 16 111 3.62E-19 T 06-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 BWK49_RS10435 f56b15e9d61955cd1da883575e76ccf8 157 Pfam PF13523 Acetyltransferase (GNAT) domain 1 137 1.2E-47 T 06-07-2017 BWK49_RS10435 f56b15e9d61955cd1da883575e76ccf8 157 SUPERFAMILY SSF55729 2 151 6.05E-44 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase BWK49_RS10435 f56b15e9d61955cd1da883575e76ccf8 157 Gene3D G3DSA:3.40.630.30 1 151 1.1E-48 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase BWK49_RS26960 0941b76c9e658dbca884046bb5da9be6 180 Pfam PF04191 Phospholipid methyltransferase 52 157 1.2E-16 T 06-07-2017 IPR007318 Phospholipid methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825|Reactome: R-HSA-1483191 BWK49_RS28135 41d65b6da13eedc0f327fbb39d5d4ce8 141 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 56 124 6.3E-19 T 06-07-2017 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal BWK49_RS28135 41d65b6da13eedc0f327fbb39d5d4ce8 141 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 19 55 1.7E-5 T 06-07-2017 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal BWK49_RS28135 41d65b6da13eedc0f327fbb39d5d4ce8 141 SUPERFAMILY SSF50249 4 130 5.48E-27 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS17485 911c7071db831613e782b85af63a4805 301 SMART SM00014 168 282 1.0E-19 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase BWK49_RS17485 911c7071db831613e782b85af63a4805 301 Pfam PF01569 PAP2 superfamily 155 284 5.4E-20 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase BWK49_RS17485 911c7071db831613e782b85af63a4805 301 SUPERFAMILY SSF48317 85 295 3.4E-35 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase BWK49_RS17485 911c7071db831613e782b85af63a4805 301 Gene3D G3DSA:1.20.144.10 112 293 3.1E-27 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase BWK49_RS11310 9356513196d086bfb3a51199a77371d3 448 Pfam PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain 52 206 1.6E-4 T 06-07-2017 IPR004255 O-acyltransferase, WSD1, N-terminal GO:0004144|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 BWK49_RS11310 9356513196d086bfb3a51199a77371d3 448 SUPERFAMILY SSF52777 31 138 1.02E-6 T 06-07-2017 BWK49_RS12980 7f3b44ca04ca808b715d704cd555a5f2 164 Hamap MF_00977 3'-5' exoribonuclease. 1 164 42.987 T 06-07-2017 IPR030853 3-5 exoribonuclease, actinobacteria GO:0000287|GO:0008408 BWK49_RS12980 7f3b44ca04ca808b715d704cd555a5f2 164 Pfam PF16473 3' exoribonuclease, RNase T-like 2 159 6.4E-17 T 06-07-2017 IPR033390 3'-5' exoribonuclease Rv2179c-like domain BWK49_RS00960 343c71b87907c69a0ea0eae1bcb5ad0f 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 70 2.7E-13 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS00960 343c71b87907c69a0ea0eae1bcb5ad0f 212 Gene3D G3DSA:1.10.10.60 21 65 1.9E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS00960 343c71b87907c69a0ea0eae1bcb5ad0f 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 40 2.2E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS00960 343c71b87907c69a0ea0eae1bcb5ad0f 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 48 71 2.2E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS00960 343c71b87907c69a0ea0eae1bcb5ad0f 212 Gene3D G3DSA:1.10.357.10 66 210 1.8E-43 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS00960 343c71b87907c69a0ea0eae1bcb5ad0f 212 SUPERFAMILY SSF46689 16 87 2.6E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS00960 343c71b87907c69a0ea0eae1bcb5ad0f 212 SUPERFAMILY SSF48498 98 209 6.5E-30 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS14030 e63d807fb0c018ebec75de701805f764 60 Gene3D G3DSA:3.50.50.60 1 26 6.2E-5 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS09015 26d9904e20fbc441e9cb5389cd984f63 99 SUPERFAMILY SSF140459 8 84 1.7E-24 T 06-07-2017 BWK49_RS09015 26d9904e20fbc441e9cb5389cd984f63 99 Pfam PF00934 PE family 2 92 1.9E-32 T 06-07-2017 IPR000084 PE-PGRS family, N-terminal BWK49_RS24245 ec57d4e9f75dafa0c12b7d11980133fd 61 SUPERFAMILY SSF57716 5 61 2.71E-21 T 06-07-2017 BWK49_RS24245 ec57d4e9f75dafa0c12b7d11980133fd 61 ProSitePatterns PS00527 Ribosomal protein S14 signature. 23 45 - T 06-07-2017 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 BWK49_RS24245 ec57d4e9f75dafa0c12b7d11980133fd 61 Pfam PF00253 Ribosomal protein S14p/S29e 9 60 4.2E-25 T 06-07-2017 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS24245 ec57d4e9f75dafa0c12b7d11980133fd 61 Gene3D G3DSA:4.10.830.10 1 61 1.4E-27 T 06-07-2017 BWK49_RS24245 ec57d4e9f75dafa0c12b7d11980133fd 61 Hamap MF_01364_B 30S ribosomal protein S14 type Z [rpsZ]. 1 61 25.606 T 06-07-2017 IPR023053 Ribosomal protein S14, type Z BWK49_RS06770 51132a45610f9c85e9cf2d0e39238488 256 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 144 249 6.6E-9 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain BWK49_RS06770 51132a45610f9c85e9cf2d0e39238488 256 SUPERFAMILY SSF54593 12 124 4.68E-18 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS06770 51132a45610f9c85e9cf2d0e39238488 256 SUPERFAMILY SSF54593 140 251 1.48E-19 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS06770 51132a45610f9c85e9cf2d0e39238488 256 Gene3D G3DSA:3.10.180.10 139 253 4.3E-29 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS06770 51132a45610f9c85e9cf2d0e39238488 256 Gene3D G3DSA:3.10.180.10 12 124 1.6E-33 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS22540 912dc65ac33dd87d34a523597bbcc91e 229 Pfam PF12697 Alpha/beta hydrolase family 1 225 2.1E-16 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS22540 912dc65ac33dd87d34a523597bbcc91e 229 SUPERFAMILY SSF53474 1 228 1.08E-31 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS22540 912dc65ac33dd87d34a523597bbcc91e 229 Gene3D G3DSA:3.40.50.1820 1 228 1.3E-36 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS15715 021c3e3b2b571aab22f44df0bfdda020 465 TIGRFAM TIGR02946 acyl_WS_DGAT: acyltransferase, WS/DGAT/MGAT 4 457 4.7E-142 T 06-07-2017 IPR014292 Acyltransferase, WS/DGAT/MGAT GO:0016746|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 BWK49_RS15715 021c3e3b2b571aab22f44df0bfdda020 465 SUPERFAMILY SSF52777 4 164 1.78E-13 T 06-07-2017 BWK49_RS15715 021c3e3b2b571aab22f44df0bfdda020 465 Pfam PF06974 Protein of unknown function (DUF1298) 307 454 2.5E-31 T 06-07-2017 IPR009721 O-acyltransferase WSD1, C-terminal GO:0004144 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 BWK49_RS15715 021c3e3b2b571aab22f44df0bfdda020 465 Pfam PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain 4 266 2.1E-78 T 06-07-2017 IPR004255 O-acyltransferase, WSD1, N-terminal GO:0004144|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 BWK49_RS02340 fe6d1efe9c24e2c5afd351e079515188 285 Gene3D G3DSA:3.40.50.720 3 269 2.0E-69 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS02340 fe6d1efe9c24e2c5afd351e079515188 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 8.5E-33 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS02340 fe6d1efe9c24e2c5afd351e079515188 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 8.5E-33 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS02340 fe6d1efe9c24e2c5afd351e079515188 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 164 8.5E-33 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS02340 fe6d1efe9c24e2c5afd351e079515188 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 195 212 8.5E-33 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS02340 fe6d1efe9c24e2c5afd351e079515188 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 232 252 8.5E-33 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS02340 fe6d1efe9c24e2c5afd351e079515188 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 194 8.5E-33 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS02340 fe6d1efe9c24e2c5afd351e079515188 285 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 162 1.3E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS02340 fe6d1efe9c24e2c5afd351e079515188 285 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 175 194 1.3E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS02340 fe6d1efe9c24e2c5afd351e079515188 285 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 1.3E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS02340 fe6d1efe9c24e2c5afd351e079515188 285 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 268 6.5E-39 T 06-07-2017 BWK49_RS02340 fe6d1efe9c24e2c5afd351e079515188 285 SUPERFAMILY SSF51735 5 269 8.8E-60 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS27935 71a0fada1a938fabb0933529c83004c8 204 Pfam PF03061 Thioesterase superfamily 118 189 2.4E-6 T 06-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 BWK49_RS27935 71a0fada1a938fabb0933529c83004c8 204 Gene3D G3DSA:3.10.129.10 78 201 3.0E-35 T 06-07-2017 IPR029069 HotDog domain BWK49_RS27935 71a0fada1a938fabb0933529c83004c8 204 SUPERFAMILY SSF54637 2 197 9.0E-43 T 06-07-2017 IPR029069 HotDog domain BWK49_RS25140 e876eea45d56b0ccae5653b9f245f2ab 325 Pfam PF01578 Cytochrome C assembly protein 108 319 2.8E-47 T 06-07-2017 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 BWK49_RS25140 e876eea45d56b0ccae5653b9f245f2ab 325 TIGRFAM TIGR03144 cytochr_II_ccsB: cytochrome c-type biogenesis protein CcsB 85 322 4.9E-77 T 06-07-2017 IPR017562 Cytochrome c-type biogenesis protein CcsA GO:0017004 BWK49_RS10970 9832dd2bbf8fe6947e6dd7e2b5e5b587 211 Gene3D G3DSA:3.40.50.850 8 207 3.6E-41 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 BWK49_RS10970 9832dd2bbf8fe6947e6dd7e2b5e5b587 211 Pfam PF00857 Isochorismatase family 15 199 8.2E-29 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 BWK49_RS10970 9832dd2bbf8fe6947e6dd7e2b5e5b587 211 SUPERFAMILY SSF52499 6 208 1.96E-40 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 BWK49_RS13590 22b3d6caf6864771e2114b673124875d 659 SUPERFAMILY SSF56317 313 583 1.57E-41 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 BWK49_RS13590 22b3d6caf6864771e2114b673124875d 659 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 140 552 8.8E-94 T 06-07-2017 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 BWK49_RS13590 22b3d6caf6864771e2114b673124875d 659 Pfam PF00795 Carbon-nitrogen hydrolase 385 561 7.9E-14 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 BWK49_RS13590 22b3d6caf6864771e2114b673124875d 659 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 85 590 14.281 T 06-07-2017 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 BWK49_RS13590 22b3d6caf6864771e2114b673124875d 659 Gene3D G3DSA:3.60.110.10 313 580 7.5E-33 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 BWK49_RS14830 05ce2e84ef32cb8bdef0a146f5d0eee2 195 Gene3D G3DSA:3.30.1020.10 164 185 4.9E-4 T 06-07-2017 BWK49_RS14830 05ce2e84ef32cb8bdef0a146f5d0eee2 195 PIRSF PIRSF000239 1 195 5.7E-48 T 06-07-2017 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 BWK49_RS14830 05ce2e84ef32cb8bdef0a146f5d0eee2 195 Gene3D G3DSA:3.40.30.10 3 163 1.8E-56 T 06-07-2017 IPR012336 Thioredoxin-like fold BWK49_RS14830 05ce2e84ef32cb8bdef0a146f5d0eee2 195 SUPERFAMILY SSF52833 4 188 1.24E-51 T 06-07-2017 IPR012336 Thioredoxin-like fold BWK49_RS14830 05ce2e84ef32cb8bdef0a146f5d0eee2 195 Pfam PF00578 AhpC/TSA family 6 146 1.4E-31 T 06-07-2017 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 BWK49_RS16455 b9c01f44cf5e07bc33b827b16b548e0f 457 Pfam PF09851 Short C-terminal domain 429 455 1.5E-6 T 06-07-2017 IPR018649 SHOCT domain BWK49_RS16455 b9c01f44cf5e07bc33b827b16b548e0f 457 Pfam PF00823 PPE family 5 161 2.1E-62 T 06-07-2017 IPR000030 PPE family BWK49_RS16455 b9c01f44cf5e07bc33b827b16b548e0f 457 SUPERFAMILY SSF140459 2 174 3.14E-64 T 06-07-2017 BWK49_RS16455 b9c01f44cf5e07bc33b827b16b548e0f 457 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 312 386 6.3E-13 T 06-07-2017 IPR022171 PPE family, C-terminal BWK49_RS12015 06c9d780c66766e1ae2bfd5bfc62fa67 143 Gene3D G3DSA:3.10.180.10 25 141 2.9E-26 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS12015 06c9d780c66766e1ae2bfd5bfc62fa67 143 SUPERFAMILY SSF54593 32 140 5.09E-19 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS27905 aa9fb089f8e5c6594df393c8958ae718 248 SUPERFAMILY SSF53335 66 239 7.43E-42 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS27905 aa9fb089f8e5c6594df393c8958ae718 248 Pfam PF08241 Methyltransferase domain 96 192 3.0E-25 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 BWK49_RS27905 aa9fb089f8e5c6594df393c8958ae718 248 Gene3D G3DSA:3.40.50.150 79 239 1.7E-42 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS20980 3ce27666eb5e1954140d874ab2018970 497 Gene3D G3DSA:3.90.1300.10 3 491 2.1E-165 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 BWK49_RS20980 3ce27666eb5e1954140d874ab2018970 497 ProSitePatterns PS00571 Amidases signature. 158 189 - T 06-07-2017 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 BWK49_RS20980 3ce27666eb5e1954140d874ab2018970 497 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 12 491 88.274 T 06-07-2017 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 BWK49_RS20980 3ce27666eb5e1954140d874ab2018970 497 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 14 487 3.8E-191 T 06-07-2017 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 BWK49_RS20980 3ce27666eb5e1954140d874ab2018970 497 Pfam PF01425 Amidase 25 479 1.5E-154 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 BWK49_RS20980 3ce27666eb5e1954140d874ab2018970 497 SUPERFAMILY SSF75304 2 488 3.53E-152 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 BWK49_RS08305 746e20238b0d798d89edc233112b6738 110 PIRSF PIRSF010611 1 110 2.0E-46 T 06-07-2017 IPR016572 Uncharacterised conserved protein UCP010611 BWK49_RS08305 746e20238b0d798d89edc233112b6738 110 TIGRFAM TIGR04529 MTB_hemophore: hemophore-related protein, Rv0203/Rv1174c family 39 110 1.8E-19 T 06-07-2017 IPR032407 Haemophore, haem-binding GO:0020037 BWK49_RS17075 d3536a7835dffa8870caec5d679a760c 249 Pfam PF00753 Metallo-beta-lactamase superfamily 57 228 6.3E-14 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS17075 d3536a7835dffa8870caec5d679a760c 249 Gene3D G3DSA:3.60.15.10 44 247 1.9E-50 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS17075 d3536a7835dffa8870caec5d679a760c 249 SMART SM00849 60 228 5.1E-31 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS17075 d3536a7835dffa8870caec5d679a760c 249 SUPERFAMILY SSF56281 54 245 3.38E-46 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS10905 55c8bf11ca1c8cb6dbd6af2d8ba924a2 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 59 2.1E-14 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS10905 55c8bf11ca1c8cb6dbd6af2d8ba924a2 200 Gene3D G3DSA:1.10.357.10 6 192 5.2E-28 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS10905 55c8bf11ca1c8cb6dbd6af2d8ba924a2 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 1.2E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS10905 55c8bf11ca1c8cb6dbd6af2d8ba924a2 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 1.2E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS10905 55c8bf11ca1c8cb6dbd6af2d8ba924a2 200 SUPERFAMILY SSF46689 5 77 1.1E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS21925 e996167821da7fe9c6d6b3f1f6df0b39 401 SUPERFAMILY SSF47203 239 395 5.15E-34 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS21925 e996167821da7fe9c6d6b3f1f6df0b39 401 Gene3D G3DSA:1.20.140.10 242 395 1.7E-47 T 06-07-2017 BWK49_RS21925 e996167821da7fe9c6d6b3f1f6df0b39 401 Gene3D G3DSA:2.40.110.10 130 236 1.0E-38 T 06-07-2017 BWK49_RS21925 e996167821da7fe9c6d6b3f1f6df0b39 401 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 241 393 9.1E-35 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS21925 e996167821da7fe9c6d6b3f1f6df0b39 401 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 130 225 1.2E-26 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 BWK49_RS21925 e996167821da7fe9c6d6b3f1f6df0b39 401 SUPERFAMILY SSF56645 16 250 1.7E-47 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS04585 2e0d97b058a3c48acc91ba0d247ce511 108 Gene3D G3DSA:1.10.260.40 8 75 5.5E-4 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 BWK49_RS04585 2e0d97b058a3c48acc91ba0d247ce511 108 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 10 77 1.1E-18 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 BWK49_RS28690 8bb9b7a17e430dc0a26e9cd7a1f3bfee 150 SUPERFAMILY SSF53098 41 111 1.67E-10 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS28690 8bb9b7a17e430dc0a26e9cd7a1f3bfee 150 Gene3D G3DSA:3.90.350.10 44 81 9.5E-5 T 06-07-2017 IPR014736 Transposase, Tn5-like, core BWK49_RS28690 8bb9b7a17e430dc0a26e9cd7a1f3bfee 150 Pfam PF13701 Transposase DDE domain group 1 41 147 1.4E-8 T 06-07-2017 IPR025668 Transposase DDE domain BWK49_RS02395 7151e16bed1557db7520f3609f64a8e6 323 SUPERFAMILY SSF53098 138 313 3.29E-33 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS02395 7151e16bed1557db7520f3609f64a8e6 323 Pfam PF00665 Integrase core domain 136 272 8.6E-31 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 BWK49_RS02395 7151e16bed1557db7520f3609f64a8e6 323 Pfam PF13011 leucine-zipper of insertion element IS481 1 82 1.7E-17 T 06-07-2017 IPR024967 DNA-binding domain, IS481-type BWK49_RS02395 7151e16bed1557db7520f3609f64a8e6 323 Gene3D G3DSA:3.30.420.10 132 309 2.6E-41 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS02395 7151e16bed1557db7520f3609f64a8e6 323 SUPERFAMILY SSF46689 6 109 2.33E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS04270 e730390823ab70a9521b6df1d933d023 223 SUPERFAMILY SSF47413 19 80 1.3E-6 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 BWK49_RS04270 e730390823ab70a9521b6df1d933d023 223 Gene3D G3DSA:1.10.260.40 21 83 1.0E-6 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 BWK49_RS08550 908f4e2f2f53dd1d170670b6b1fd332f 400 Gene3D G3DSA:1.10.530.10 76 206 1.5E-9 T 06-07-2017 BWK49_RS08550 908f4e2f2f53dd1d170670b6b1fd332f 400 Pfam PF13406 Transglycosylase SLT domain 140 188 8.1E-8 T 06-07-2017 IPR031304 Transglycosylase SLT domain 2 BWK49_RS08550 908f4e2f2f53dd1d170670b6b1fd332f 400 SUPERFAMILY SSF53955 26 224 2.25E-36 T 06-07-2017 IPR023346 Lysozyme-like domain BWK49_RS08735 69363627e0ebd0b8ae23d62d6e3c6663 638 Pfam PF00664 ABC transporter transmembrane region 54 353 2.1E-58 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 BWK49_RS08735 69363627e0ebd0b8ae23d62d6e3c6663 638 Gene3D G3DSA:3.40.50.300 404 635 3.3E-81 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS08735 69363627e0ebd0b8ae23d62d6e3c6663 638 SUPERFAMILY SSF90123 29 67 1.83E-80 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 BWK49_RS08735 69363627e0ebd0b8ae23d62d6e3c6663 638 SUPERFAMILY SSF90123 107 386 1.83E-80 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 BWK49_RS08735 69363627e0ebd0b8ae23d62d6e3c6663 638 SMART SM00382 429 615 1.4E-16 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS08735 69363627e0ebd0b8ae23d62d6e3c6663 638 Gene3D G3DSA:1.20.1560.10 110 384 2.2E-84 T 06-07-2017 BWK49_RS08735 69363627e0ebd0b8ae23d62d6e3c6663 638 Gene3D G3DSA:1.20.1560.10 29 72 2.2E-84 T 06-07-2017 BWK49_RS08735 69363627e0ebd0b8ae23d62d6e3c6663 638 Pfam PF00005 ABC transporter 421 569 5.7E-31 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 BWK49_RS08735 69363627e0ebd0b8ae23d62d6e3c6663 638 SUPERFAMILY SSF52540 399 636 1.11E-89 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS08735 69363627e0ebd0b8ae23d62d6e3c6663 638 ProSitePatterns PS00211 ABC transporters family signature. 541 555 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 BWK49_RS24175 df0f975ed7726c9c498a61b100fbbf97 305 Gene3D G3DSA:3.60.15.10 47 289 1.5E-37 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS24175 df0f975ed7726c9c498a61b100fbbf97 305 SMART SM00849 56 278 5.9E-19 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS24175 df0f975ed7726c9c498a61b100fbbf97 305 SUPERFAMILY SSF56281 48 295 2.57E-32 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS24175 df0f975ed7726c9c498a61b100fbbf97 305 Pfam PF00753 Metallo-beta-lactamase superfamily 58 278 3.9E-18 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS01790 66977542e07f3e10c2504900392291cc 269 Gene3D G3DSA:3.30.450.40 98 269 2.2E-53 T 06-07-2017 IPR029016 GAF domain-like BWK49_RS01790 66977542e07f3e10c2504900392291cc 269 Gene3D G3DSA:1.10.10.10 23 95 1.3E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS01790 66977542e07f3e10c2504900392291cc 269 SMART SM00346 25 114 1.1E-13 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 BWK49_RS01790 66977542e07f3e10c2504900392291cc 269 Pfam PF09339 IclR helix-turn-helix domain 27 77 1.8E-12 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 BWK49_RS01790 66977542e07f3e10c2504900392291cc 269 SUPERFAMILY SSF55781 82 269 2.03E-46 T 06-07-2017 IPR029016 GAF domain-like BWK49_RS01790 66977542e07f3e10c2504900392291cc 269 SUPERFAMILY SSF46785 25 96 1.15E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS01790 66977542e07f3e10c2504900392291cc 269 Pfam PF01614 Bacterial transcriptional regulator 141 264 8.6E-29 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal BWK49_RS08500 4d0f7019e7441c2eb66ad10598101b10 224 Pfam PF04191 Phospholipid methyltransferase 111 201 8.6E-16 T 06-07-2017 IPR007318 Phospholipid methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825|Reactome: R-HSA-1483191 BWK49_RS14795 c3bfe6f3e2a7dea5736c08978e7bc585 683 Gene3D G3DSA:1.20.1250.20 475 502 4.6E-19 T 06-07-2017 BWK49_RS14795 c3bfe6f3e2a7dea5736c08978e7bc585 683 Gene3D G3DSA:1.20.1250.20 23 197 6.6E-33 T 06-07-2017 BWK49_RS14795 c3bfe6f3e2a7dea5736c08978e7bc585 683 Gene3D G3DSA:1.20.1250.20 276 432 4.6E-19 T 06-07-2017 BWK49_RS14795 c3bfe6f3e2a7dea5736c08978e7bc585 683 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 25 431 2.1E-70 T 06-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 BWK49_RS14795 c3bfe6f3e2a7dea5736c08978e7bc585 683 Pfam PF07690 Major Facilitator Superfamily 30 422 6.2E-45 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 BWK49_RS14795 c3bfe6f3e2a7dea5736c08978e7bc585 683 SUPERFAMILY SSF103473 20 213 1.27E-66 T 06-07-2017 IPR020846 Major facilitator superfamily domain BWK49_RS14795 c3bfe6f3e2a7dea5736c08978e7bc585 683 SUPERFAMILY SSF103473 474 501 1.27E-66 T 06-07-2017 IPR020846 Major facilitator superfamily domain BWK49_RS14795 c3bfe6f3e2a7dea5736c08978e7bc585 683 SUPERFAMILY SSF103473 260 431 1.27E-66 T 06-07-2017 IPR020846 Major facilitator superfamily domain BWK49_RS14795 c3bfe6f3e2a7dea5736c08978e7bc585 683 PRINTS PR01036 Tetracycline resistance protein TetB signature 118 138 9.4E-5 T 06-07-2017 BWK49_RS14795 c3bfe6f3e2a7dea5736c08978e7bc585 683 PRINTS PR01036 Tetracycline resistance protein TetB signature 148 172 9.4E-5 T 06-07-2017 BWK49_RS14795 c3bfe6f3e2a7dea5736c08978e7bc585 683 PRINTS PR01036 Tetracycline resistance protein TetB signature 349 369 9.4E-5 T 06-07-2017 BWK49_RS14795 c3bfe6f3e2a7dea5736c08978e7bc585 683 PRINTS PR01036 Tetracycline resistance protein TetB signature 412 431 9.4E-5 T 06-07-2017 BWK49_RS14795 c3bfe6f3e2a7dea5736c08978e7bc585 683 ProSitePatterns PS00217 Sugar transport proteins signature 2. 120 145 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 BWK49_RS04915 0a578658b9f5a1dc5750fe530cb03b94 289 Pfam PF02405 Permease MlaE 71 275 1.7E-51 T 06-07-2017 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 BWK49_RS22295 1114acc6060764c411187b2cd3b3b539 178 Pfam PF07098 Protein of unknown function (DUF1360) 69 169 1.9E-35 T 06-07-2017 IPR010773 Mycobacterium phage PG1, Gp7 BWK49_RS06015 b1910073cf0e4d12ee0d6b95e7800479 326 SUPERFAMILY SSF52096 11 252 2.74E-36 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS06015 b1910073cf0e4d12ee0d6b95e7800479 326 Gene3D G3DSA:3.90.226.10 6 262 3.2E-43 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS06015 b1910073cf0e4d12ee0d6b95e7800479 326 Pfam PF00378 Enoyl-CoA hydratase/isomerase 127 249 7.7E-12 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 BWK49_RS03475 b63374f649f9c0c20c6391d32d04386e 260 Gene3D G3DSA:3.40.50.720 3 256 1.7E-70 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS03475 b63374f649f9c0c20c6391d32d04386e 260 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 256 1.1E-53 T 06-07-2017 BWK49_RS03475 b63374f649f9c0c20c6391d32d04386e 260 SUPERFAMILY SSF51735 6 257 3.9E-70 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS03475 b63374f649f9c0c20c6391d32d04386e 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 1.1E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS03475 b63374f649f9c0c20c6391d32d04386e 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 1.1E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS03475 b63374f649f9c0c20c6391d32d04386e 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 1.1E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS03475 b63374f649f9c0c20c6391d32d04386e 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.1E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS03475 b63374f649f9c0c20c6391d32d04386e 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 1.1E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS03475 b63374f649f9c0c20c6391d32d04386e 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 1.1E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS03475 b63374f649f9c0c20c6391d32d04386e 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 221 241 1.1E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS03475 b63374f649f9c0c20c6391d32d04386e 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 1.1E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS03475 b63374f649f9c0c20c6391d32d04386e 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 1.1E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS01115 5df561083cd9d1f32db0f9eda4bd9ac2 270 Gene3D G3DSA:3.40.50.1000 1 73 5.8E-53 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS01115 5df561083cd9d1f32db0f9eda4bd9ac2 270 Gene3D G3DSA:3.40.50.1000 173 269 5.8E-53 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS01115 5df561083cd9d1f32db0f9eda4bd9ac2 270 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 238 2.5E-23 T 06-07-2017 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 BWK49_RS01115 5df561083cd9d1f32db0f9eda4bd9ac2 270 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 265 1.2E-60 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS01115 5df561083cd9d1f32db0f9eda4bd9ac2 270 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 265 6.5E-49 T 06-07-2017 IPR000150 Cof protein GO:0016787 BWK49_RS01115 5df561083cd9d1f32db0f9eda4bd9ac2 270 SUPERFAMILY SSF56784 1 269 2.76E-65 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS00870 5d70bb0d5d2505906627d0d073924a11 341 SUPERFAMILY SSF52540 90 303 5.32E-20 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS00870 5d70bb0d5d2505906627d0d073924a11 341 Gene3D G3DSA:3.40.50.300 89 303 1.5E-21 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS20020 7d0817407ef53ae6908dcdd7c69de181 319 SUPERFAMILY SSF140459 2 169 4.71E-50 T 06-07-2017 BWK49_RS20020 7d0817407ef53ae6908dcdd7c69de181 319 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 265 296 9.0E-5 T 06-07-2017 IPR022171 PPE family, C-terminal BWK49_RS20020 7d0817407ef53ae6908dcdd7c69de181 319 Pfam PF00823 PPE family 6 159 1.3E-48 T 06-07-2017 IPR000030 PPE family BWK49_RS21210 59fe862c91d54dc2142e16cd6195b9b6 703 SUPERFAMILY SSF82866 115 342 1.96E-31 T 06-07-2017 BWK49_RS21210 59fe862c91d54dc2142e16cd6195b9b6 703 SUPERFAMILY SSF82866 475 680 9.42E-26 T 06-07-2017 BWK49_RS21210 59fe862c91d54dc2142e16cd6195b9b6 703 Pfam PF03176 MMPL family 50 371 1.5E-55 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 BWK49_RS21210 59fe862c91d54dc2142e16cd6195b9b6 703 Pfam PF03176 MMPL family 478 682 8.4E-42 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 BWK49_RS21210 59fe862c91d54dc2142e16cd6195b9b6 703 Gene3D G3DSA:1.20.1640.10 135 342 5.6E-27 T 06-07-2017 BWK49_RS21210 59fe862c91d54dc2142e16cd6195b9b6 703 Gene3D G3DSA:1.20.1640.10 505 683 3.7E-21 T 06-07-2017 BWK49_RS22850 9d3f30f4921ee02bde2cb6f96f1fef94 164 Gene3D G3DSA:3.30.310.70 42 160 6.1E-28 T 06-07-2017 IPR005180 Domain of unknown function DUF302 BWK49_RS22850 9d3f30f4921ee02bde2cb6f96f1fef94 164 Pfam PF03625 Domain of unknown function DUF302 69 130 1.5E-9 T 06-07-2017 IPR005180 Domain of unknown function DUF302 BWK49_RS22850 9d3f30f4921ee02bde2cb6f96f1fef94 164 SUPERFAMILY SSF103247 42 160 3.66E-22 T 06-07-2017 IPR005180 Domain of unknown function DUF302 BWK49_RS08470 3f481416cebb0719c95c35de485f5914 332 SUPERFAMILY SSF53448 50 290 1.76E-54 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases BWK49_RS08470 3f481416cebb0719c95c35de485f5914 332 Gene3D G3DSA:3.90.550.10 50 158 3.0E-11 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases BWK49_RS08470 3f481416cebb0719c95c35de485f5914 332 Pfam PF00535 Glycosyl transferase family 2 51 157 2.7E-9 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 BWK49_RS23505 e78b513ee2f1800f787eee73971d2e24 413 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 18 399 1.4E-70 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 BWK49_RS23505 e78b513ee2f1800f787eee73971d2e24 413 SMART SM01329 16 403 1.0E-129 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 BWK49_RS23505 e78b513ee2f1800f787eee73971d2e24 413 SUPERFAMILY SSF53659 9 411 1.4E-150 T 06-07-2017 BWK49_RS23505 e78b513ee2f1800f787eee73971d2e24 413 Gene3D G3DSA:3.40.718.10 10 411 1.6E-170 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 BWK49_RS23505 e78b513ee2f1800f787eee73971d2e24 413 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 278 297 - T 06-07-2017 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 BWK49_RS23505 e78b513ee2f1800f787eee73971d2e24 413 TIGRFAM TIGR00127 nadp_idh_euk: isocitrate dehydrogenase, NADP-dependent 10 412 6.6E-205 T 06-07-2017 IPR004790 Isocitrate dehydrogenase NADP-dependent GO:0004450|GO:0006102|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 BWK49_RS23505 e78b513ee2f1800f787eee73971d2e24 413 PIRSF PIRSF000108 2 413 2.3E-221 T 06-07-2017 IPR004790 Isocitrate dehydrogenase NADP-dependent GO:0004450|GO:0006102|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 BWK49_RS24330 eb57eff24af29fb609c9c143b5107054 101 SMART SM01403 7 101 1.7E-54 T 06-07-2017 IPR027486 Ribosomal protein S10 domain BWK49_RS24330 eb57eff24af29fb609c9c143b5107054 101 Gene3D G3DSA:3.30.70.600 4 100 4.2E-42 T 06-07-2017 IPR027486 Ribosomal protein S10 domain BWK49_RS24330 eb57eff24af29fb609c9c143b5107054 101 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 3.7E-21 T 06-07-2017 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 BWK49_RS24330 eb57eff24af29fb609c9c143b5107054 101 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 3.7E-21 T 06-07-2017 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 BWK49_RS24330 eb57eff24af29fb609c9c143b5107054 101 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 3.7E-21 T 06-07-2017 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 BWK49_RS24330 eb57eff24af29fb609c9c143b5107054 101 SUPERFAMILY SSF54999 5 100 3.53E-36 T 06-07-2017 IPR027486 Ribosomal protein S10 domain BWK49_RS24330 eb57eff24af29fb609c9c143b5107054 101 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 06-07-2017 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 BWK49_RS24330 eb57eff24af29fb609c9c143b5107054 101 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 101 24.326 T 06-07-2017 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 BWK49_RS24330 eb57eff24af29fb609c9c143b5107054 101 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 1.2E-45 T 06-07-2017 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 BWK49_RS24330 eb57eff24af29fb609c9c143b5107054 101 Pfam PF00338 Ribosomal protein S10p/S20e 7 100 3.4E-34 T 06-07-2017 IPR027486 Ribosomal protein S10 domain BWK49_RS08425 46739d9dbe003ad8fd77af04188e6c18 421 ProSitePatterns PS00217 Sugar transport proteins signature 2. 115 140 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 BWK49_RS08425 46739d9dbe003ad8fd77af04188e6c18 421 SUPERFAMILY SSF103473 2 412 9.29E-56 T 06-07-2017 IPR020846 Major facilitator superfamily domain BWK49_RS08425 46739d9dbe003ad8fd77af04188e6c18 421 Gene3D G3DSA:1.20.1250.20 3 211 5.5E-21 T 06-07-2017 BWK49_RS08425 46739d9dbe003ad8fd77af04188e6c18 421 Gene3D G3DSA:1.20.1250.20 227 414 1.1E-18 T 06-07-2017 BWK49_RS08425 46739d9dbe003ad8fd77af04188e6c18 421 Pfam PF07690 Major Facilitator Superfamily 21 376 1.0E-27 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 BWK49_RS09275 e15978ebd595c953d2b1e3438a598cd9 265 Gene3D G3DSA:3.40.50.720 2 261 2.9E-59 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS09275 e15978ebd595c953d2b1e3438a598cd9 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 7.1E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS09275 e15978ebd595c953d2b1e3438a598cd9 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 7.1E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS09275 e15978ebd595c953d2b1e3438a598cd9 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 7.1E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS09275 e15978ebd595c953d2b1e3438a598cd9 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 7.1E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS09275 e15978ebd595c953d2b1e3438a598cd9 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 226 246 7.1E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS09275 e15978ebd595c953d2b1e3438a598cd9 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 7.1E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS09275 e15978ebd595c953d2b1e3438a598cd9 265 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 261 1.3E-42 T 06-07-2017 BWK49_RS09275 e15978ebd595c953d2b1e3438a598cd9 265 SUPERFAMILY SSF51735 10 261 5.84E-59 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS12945 3a56088d0fc35514afef9f9aa57a8b6b 132 SUPERFAMILY SSF55961 5 96 5.18E-7 T 06-07-2017 BWK49_RS24055 f87e519435f1515f30448c296158f20a 205 Gene3D G3DSA:2.60.120.10 2 191 2.8E-71 T 06-07-2017 IPR014710 RmlC-like jelly roll fold BWK49_RS24055 f87e519435f1515f30448c296158f20a 205 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 6 178 7.1E-63 T 06-07-2017 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 BWK49_RS24055 f87e519435f1515f30448c296158f20a 205 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 1 184 5.0E-97 T 06-07-2017 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 BWK49_RS24055 f87e519435f1515f30448c296158f20a 205 SUPERFAMILY SSF51182 2 197 1.09E-72 T 06-07-2017 IPR011051 RmlC-like cupin domain BWK49_RS24055 f87e519435f1515f30448c296158f20a 205 TIGRFAM TIGR01221 rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase 3 180 1.9E-49 T 06-07-2017 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 BWK49_RS11575 8ad270ff16dbde28920f226f9e5d6017 267 Gene3D G3DSA:3.40.50.300 5 266 1.6E-105 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS11575 8ad270ff16dbde28920f226f9e5d6017 267 Pfam PF09037 Stf0 sulphotransferase 7 259 2.3E-105 T 06-07-2017 IPR024628 Sulphotransferase Stf0, domain BWK49_RS11575 8ad270ff16dbde28920f226f9e5d6017 267 PIRSF PIRSF021497 1 267 3.9E-112 T 06-07-2017 IPR015124 Trehalose 2-sulfotransferase GO:0016740 BWK49_RS11575 8ad270ff16dbde28920f226f9e5d6017 267 SUPERFAMILY SSF52540 4 266 4.18E-92 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS14270 ddbc123f44b64dae4a9ecaa591e0f1b0 185 Gene3D G3DSA:1.10.1470.10 13 68 3.1E-7 T 06-07-2017 IPR008462 CsbD-like BWK49_RS14270 ddbc123f44b64dae4a9ecaa591e0f1b0 185 SUPERFAMILY SSF69047 10 65 1.06E-6 T 06-07-2017 IPR008462 CsbD-like BWK49_RS24865 4aa2f5c0fe66285486162f7a119c9564 382 PIRSF PIRSF000429 1 381 1.4E-38 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 BWK49_RS24865 4aa2f5c0fe66285486162f7a119c9564 382 Gene3D G3DSA:3.40.47.10 241 381 6.3E-20 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS24865 4aa2f5c0fe66285486162f7a119c9564 382 Gene3D G3DSA:3.40.47.10 134 175 6.3E-20 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS24865 4aa2f5c0fe66285486162f7a119c9564 382 Pfam PF00108 Thiolase, N-terminal domain 7 174 2.1E-10 T 06-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 BWK49_RS24865 4aa2f5c0fe66285486162f7a119c9564 382 Pfam PF02803 Thiolase, C-terminal domain 253 379 1.5E-8 T 06-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 BWK49_RS24865 4aa2f5c0fe66285486162f7a119c9564 382 SUPERFAMILY SSF53901 250 360 2.69E-25 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS24865 4aa2f5c0fe66285486162f7a119c9564 382 Gene3D G3DSA:3.40.47.10 186 216 1.0E-13 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS24865 4aa2f5c0fe66285486162f7a119c9564 382 Gene3D G3DSA:3.40.47.10 17 107 1.0E-13 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS24865 4aa2f5c0fe66285486162f7a119c9564 382 SUPERFAMILY SSF53901 6 220 1.56E-33 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS15375 30141305a78e39ba764f67ae38a4f9d7 335 Gene3D G3DSA:3.40.50.970 10 329 6.6E-106 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS15375 30141305a78e39ba764f67ae38a4f9d7 335 SUPERFAMILY SSF52518 13 330 1.97E-88 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold BWK49_RS15375 30141305a78e39ba764f67ae38a4f9d7 335 Pfam PF00676 Dehydrogenase E1 component 26 311 1.6E-72 T 06-07-2017 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 BWK49_RS21880 249d1880b88195748c8a578f11d455fc 268 Pfam PF00582 Universal stress protein family 9 138 2.6E-16 T 06-07-2017 IPR006016 UspA GO:0006950 BWK49_RS21880 249d1880b88195748c8a578f11d455fc 268 Gene3D G3DSA:3.40.50.620 132 230 9.3E-8 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold BWK49_RS21880 249d1880b88195748c8a578f11d455fc 268 SUPERFAMILY SSF52402 9 140 1.42E-18 T 06-07-2017 BWK49_RS21880 249d1880b88195748c8a578f11d455fc 268 Gene3D G3DSA:3.40.50.620 5 131 3.2E-20 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold BWK49_RS19490 aabd1c1031c28c52f338f5ba9003403e 343 Pfam PF12697 Alpha/beta hydrolase family 42 289 7.6E-25 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS19490 aabd1c1031c28c52f338f5ba9003403e 343 SUPERFAMILY SSF53474 19 296 4.76E-62 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS19490 aabd1c1031c28c52f338f5ba9003403e 343 PRINTS PR00111 Alpha/beta hydrolase fold signature 123 136 1.0E-12 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS19490 aabd1c1031c28c52f338f5ba9003403e 343 PRINTS PR00111 Alpha/beta hydrolase fold signature 65 80 1.0E-12 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS19490 aabd1c1031c28c52f338f5ba9003403e 343 PRINTS PR00111 Alpha/beta hydrolase fold signature 109 122 1.0E-12 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS19490 aabd1c1031c28c52f338f5ba9003403e 343 Gene3D G3DSA:3.40.50.1820 23 297 4.4E-63 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS13155 1b079baaf42a8658d57f5444313cfb29 176 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 41 173 1.2E-38 T 06-07-2017 IPR005247 YbhB/YbcL BWK49_RS13155 1b079baaf42a8658d57f5444313cfb29 176 Pfam PF01161 Phosphatidylethanolamine-binding protein 42 173 7.6E-37 T 06-07-2017 IPR008914 Phosphatidylethanolamine-binding protein BWK49_RS13155 1b079baaf42a8658d57f5444313cfb29 176 SUPERFAMILY SSF49777 17 174 6.93E-50 T 06-07-2017 IPR008914 Phosphatidylethanolamine-binding protein BWK49_RS13155 1b079baaf42a8658d57f5444313cfb29 176 Gene3D G3DSA:3.90.280.10 16 175 7.2E-53 T 06-07-2017 IPR008914 Phosphatidylethanolamine-binding protein BWK49_RS00925 1b6abf6ddddef37ed37785194b7e92e0 491 SUPERFAMILY SSF51971 143 407 1.82E-69 T 06-07-2017 BWK49_RS00925 1b6abf6ddddef37ed37785194b7e92e0 491 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 145 462 3.8E-26 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS00925 1b6abf6ddddef37ed37785194b7e92e0 491 SUPERFAMILY SSF46548 10 155 6.28E-40 T 06-07-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 BWK49_RS00925 1b6abf6ddddef37ed37785194b7e92e0 491 Gene3D G3DSA:3.50.50.60 385 475 3.5E-15 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS00925 1b6abf6ddddef37ed37785194b7e92e0 491 TIGRFAM TIGR01317 GOGAT_sm_gam: glutamate synthase, NADH/NADPH, small subunit 3 480 7.6E-233 T 06-07-2017 IPR006005 Glutamate synthase, NADH/NADPH, small subunit 1 GO:0006537|GO:0016639|GO:0055114 BWK49_RS00925 1b6abf6ddddef37ed37785194b7e92e0 491 Gene3D G3DSA:3.40.50.720 147 384 1.3E-60 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS00925 1b6abf6ddddef37ed37785194b7e92e0 491 Gene3D G3DSA:1.10.1060.10 11 146 7.2E-40 T 06-07-2017 BWK49_RS00925 1b6abf6ddddef37ed37785194b7e92e0 491 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 26 132 5.1E-24 T 06-07-2017 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 BWK49_RS00925 1b6abf6ddddef37ed37785194b7e92e0 491 PRINTS PR00419 Adrenodoxin reductase family signature 169 182 4.6E-24 T 06-07-2017 BWK49_RS00925 1b6abf6ddddef37ed37785194b7e92e0 491 PRINTS PR00419 Adrenodoxin reductase family signature 211 221 4.6E-24 T 06-07-2017 BWK49_RS00925 1b6abf6ddddef37ed37785194b7e92e0 491 PRINTS PR00419 Adrenodoxin reductase family signature 293 307 4.6E-24 T 06-07-2017 BWK49_RS00925 1b6abf6ddddef37ed37785194b7e92e0 491 PRINTS PR00419 Adrenodoxin reductase family signature 146 168 4.6E-24 T 06-07-2017 BWK49_RS00485 99c6fe670df785f4a0a9da7cc51ec904 452 SUPERFAMILY SSF48264 18 415 1.2E-72 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS00485 99c6fe670df785f4a0a9da7cc51ec904 452 Gene3D G3DSA:1.10.630.10 17 415 4.4E-87 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS00485 99c6fe670df785f4a0a9da7cc51ec904 452 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 356 365 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 BWK49_RS00485 99c6fe670df785f4a0a9da7cc51ec904 452 PRINTS PR00359 B-class P450 signature 354 363 6.1E-25 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS00485 99c6fe670df785f4a0a9da7cc51ec904 452 PRINTS PR00359 B-class P450 signature 149 165 6.1E-25 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS00485 99c6fe670df785f4a0a9da7cc51ec904 452 PRINTS PR00359 B-class P450 signature 103 114 6.1E-25 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS00485 99c6fe670df785f4a0a9da7cc51ec904 452 PRINTS PR00359 B-class P450 signature 288 299 6.1E-25 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS00485 99c6fe670df785f4a0a9da7cc51ec904 452 PRINTS PR00359 B-class P450 signature 305 332 6.1E-25 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS00485 99c6fe670df785f4a0a9da7cc51ec904 452 PRINTS PR00359 B-class P450 signature 333 348 6.1E-25 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS00485 99c6fe670df785f4a0a9da7cc51ec904 452 PRINTS PR00359 B-class P450 signature 363 374 6.1E-25 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS00485 99c6fe670df785f4a0a9da7cc51ec904 452 Pfam PF00067 Cytochrome P450 224 383 4.2E-16 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS18275 477d356d6983e027a8dc717f52e4d710 581 Pfam PF12077 Transmembrane protein of unknown function (DUF3556) 1 575 5.3E-264 T 06-07-2017 IPR021941 Protein of unknown function DUF3556, transmembrane BWK49_RS15825 81a59d61fa483dcd9fd80d3147a507d8 379 Gene3D G3DSA:1.10.540.10 17 129 1.4E-24 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS15825 81a59d61fa483dcd9fd80d3147a507d8 379 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 134 146 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 BWK49_RS15825 81a59d61fa483dcd9fd80d3147a507d8 379 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 17 128 2.9E-24 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS15825 81a59d61fa483dcd9fd80d3147a507d8 379 Gene3D G3DSA:1.20.140.10 230 334 2.6E-6 T 06-07-2017 BWK49_RS15825 81a59d61fa483dcd9fd80d3147a507d8 379 SUPERFAMILY SSF56645 18 250 3.27E-61 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS15825 81a59d61fa483dcd9fd80d3147a507d8 379 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 133 217 4.9E-18 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 BWK49_RS15825 81a59d61fa483dcd9fd80d3147a507d8 379 Gene3D G3DSA:2.40.110.10 132 229 1.9E-26 T 06-07-2017 BWK49_RS04630 0bf7e50a49f2f1703857903ed3b5c8a8 981 SUPERFAMILY SSF82866 117 331 3.66E-30 T 06-07-2017 BWK49_RS04630 0bf7e50a49f2f1703857903ed3b5c8a8 981 Pfam PF03176 MMPL family 32 358 1.2E-84 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 BWK49_RS04630 0bf7e50a49f2f1703857903ed3b5c8a8 981 Pfam PF03176 MMPL family 654 969 5.9E-72 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 BWK49_RS04630 0bf7e50a49f2f1703857903ed3b5c8a8 981 SUPERFAMILY SSF82866 763 965 6.02E-20 T 06-07-2017 BWK49_RS04630 0bf7e50a49f2f1703857903ed3b5c8a8 981 Gene3D G3DSA:1.20.1640.10 764 969 7.7E-19 T 06-07-2017 BWK49_RS04630 0bf7e50a49f2f1703857903ed3b5c8a8 981 Gene3D G3DSA:1.20.1640.10 132 337 4.6E-30 T 06-07-2017 BWK49_RS04630 0bf7e50a49f2f1703857903ed3b5c8a8 981 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 660 683 5.9E-7 T 06-07-2017 IPR023908 xxxLxxG heptad repeat BWK49_RS14640 582b1a3967d69edf842e880b160ef7a3 465 ProDom PD008243 RV1792C/MT1741/MB1728C RV1945/MT1995 MB1980 MB0098C RV3466/MT3572 VERY RV1128C/MT1160 RV1148C/MT1183 MB1159C RV0095C 25 95 1.0E-16 T 06-07-2017 BWK49_RS14640 582b1a3967d69edf842e880b160ef7a3 465 Pfam PF02720 Domain of unknown function (DUF222) 40 364 7.3E-95 T 06-07-2017 IPR003870 Domain of unknown function DUF222 BWK49_RS14640 582b1a3967d69edf842e880b160ef7a3 465 SMART SM00507 355 407 7.9E-5 T 06-07-2017 IPR003615 HNH nuclease BWK49_RS13260 83d6a8f1d2b773150067339574e2e489 292 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 187 3.4E-6 T 06-07-2017 BWK49_RS13260 83d6a8f1d2b773150067339574e2e489 292 SUPERFAMILY SSF51735 1 253 3.82E-67 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS13260 83d6a8f1d2b773150067339574e2e489 292 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 4.0E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS13260 83d6a8f1d2b773150067339574e2e489 292 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 4.0E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS13260 83d6a8f1d2b773150067339574e2e489 292 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 4.0E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS13260 83d6a8f1d2b773150067339574e2e489 292 Gene3D G3DSA:3.40.50.720 6 237 5.7E-67 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS13260 83d6a8f1d2b773150067339574e2e489 292 Pfam PF00106 short chain dehydrogenase 8 195 2.2E-51 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS13260 83d6a8f1d2b773150067339574e2e489 292 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 1.6E-21 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS13260 83d6a8f1d2b773150067339574e2e489 292 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 1.6E-21 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS13260 83d6a8f1d2b773150067339574e2e489 292 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 1.6E-21 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS13260 83d6a8f1d2b773150067339574e2e489 292 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 1.6E-21 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS13260 83d6a8f1d2b773150067339574e2e489 292 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.6E-21 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS13260 83d6a8f1d2b773150067339574e2e489 292 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS18160 fa4866fce8dc0f9a19722a9bd88a7e61 482 SUPERFAMILY SSF101960 49 479 1.05E-140 T 06-07-2017 BWK49_RS18160 fa4866fce8dc0f9a19722a9bd88a7e61 482 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 27 473 5.2E-218 T 06-07-2017 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 BWK49_RS18160 fa4866fce8dc0f9a19722a9bd88a7e61 482 Pfam PF01458 Uncharacterized protein family (UPF0051) 228 453 4.1E-77 T 06-07-2017 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 BWK49_RS22775 157230fc99fa09f487c99344e4a5efa0 282 Gene3D G3DSA:3.40.50.720 1 242 4.6E-48 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS22775 157230fc99fa09f487c99344e4a5efa0 282 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 8.1E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS22775 157230fc99fa09f487c99344e4a5efa0 282 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 181 8.1E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS22775 157230fc99fa09f487c99344e4a5efa0 282 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 8.1E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS22775 157230fc99fa09f487c99344e4a5efa0 282 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 8.1E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS22775 157230fc99fa09f487c99344e4a5efa0 282 Pfam PF00106 short chain dehydrogenase 6 202 6.8E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS22775 157230fc99fa09f487c99344e4a5efa0 282 SUPERFAMILY SSF51735 1 242 3.84E-48 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS14780 57ec5089adf332c526a757446b7a8457 450 SMART SM01230 111 358 3.3E-69 T 06-07-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 BWK49_RS14780 57ec5089adf332c526a757446b7a8457 450 SUPERFAMILY SSF55931 111 437 5.4E-79 T 06-07-2017 BWK49_RS14780 57ec5089adf332c526a757446b7a8457 450 Gene3D G3DSA:3.30.590.10 115 433 4.6E-76 T 06-07-2017 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 BWK49_RS14780 57ec5089adf332c526a757446b7a8457 450 Pfam PF00120 Glutamine synthetase, catalytic domain 112 432 7.5E-64 T 06-07-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 BWK49_RS26600 890c6a8f25e143c696e6b2035229d714 222 SMART SM00796 19 211 3.5E-84 T 06-07-2017 IPR003833 Carboxyltransferase domain, subdomain C and D BWK49_RS26600 890c6a8f25e143c696e6b2035229d714 222 Gene3D G3DSA:2.40.100.10 100 222 6.7E-46 T 06-07-2017 IPR029000 Cyclophilin-like domain BWK49_RS26600 890c6a8f25e143c696e6b2035229d714 222 Gene3D G3DSA:3.30.1360.40 24 69 1.2E-7 T 06-07-2017 IPR024946 Arginine repressor C-terminal-like domain BWK49_RS26600 890c6a8f25e143c696e6b2035229d714 222 SUPERFAMILY SSF50891 100 222 1.74E-39 T 06-07-2017 IPR029000 Cyclophilin-like domain BWK49_RS26600 890c6a8f25e143c696e6b2035229d714 222 SUPERFAMILY SSF160467 23 72 1.7E-8 T 06-07-2017 BWK49_RS26600 890c6a8f25e143c696e6b2035229d714 222 Pfam PF02682 Allophanate hydrolase subunit 1 22 211 9.9E-64 T 06-07-2017 IPR003833 Carboxyltransferase domain, subdomain C and D BWK49_RS11695 f5771dc67b4a1ba57f737e4c5508b75e 750 Pfam PF13481 AAA domain 373 551 3.4E-24 T 06-07-2017 BWK49_RS11695 f5771dc67b4a1ba57f737e4c5508b75e 750 Gene3D G3DSA:3.40.50.300 375 553 3.0E-22 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS11695 f5771dc67b4a1ba57f737e4c5508b75e 750 SUPERFAMILY SSF56747 26 102 7.19E-5 T 06-07-2017 BWK49_RS11695 f5771dc67b4a1ba57f737e4c5508b75e 750 SUPERFAMILY SSF52540 388 576 3.64E-8 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS17525 0f4db384c1542b9c006ec86431c02b37 153 Gene3D G3DSA:2.30.110.10 9 150 1.0E-9 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 BWK49_RS17525 0f4db384c1542b9c006ec86431c02b37 153 SUPERFAMILY SSF50475 9 114 9.82E-15 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 BWK49_RS17525 0f4db384c1542b9c006ec86431c02b37 153 TIGRFAM TIGR03666 Rv2061_F420: PPOX class probable F420-dependent enzyme, Rv2061 family 9 151 3.5E-44 T 06-07-2017 IPR019965 PPOX class F420-dependent enzyme, family Rv2061, putative BWK49_RS06520 737f905f935089fd6186d456174de6fe 178 Gene3D G3DSA:1.10.357.10 4 176 1.3E-29 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS06520 737f905f935089fd6186d456174de6fe 178 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 57 3.1E-16 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS06520 737f905f935089fd6186d456174de6fe 178 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 5.5E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS06520 737f905f935089fd6186d456174de6fe 178 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 5.5E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS06520 737f905f935089fd6186d456174de6fe 178 SUPERFAMILY SSF46689 2 69 2.39E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS23595 c44ca3faff11678ed72e2b547843d234 201 Gene3D G3DSA:3.40.50.150 19 199 4.5E-30 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS23595 c44ca3faff11678ed72e2b547843d234 201 Pfam PF13649 Methyltransferase domain 52 147 2.1E-13 T 06-07-2017 BWK49_RS23595 c44ca3faff11678ed72e2b547843d234 201 SUPERFAMILY SSF53335 14 187 5.18E-27 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS11270 284c02ba27a4cea91fbb319546f94d64 253 PRINTS PR00721 Stomatin signature 128 151 1.0E-60 T 06-07-2017 IPR001972 Stomatin family GO:0016020 BWK49_RS11270 284c02ba27a4cea91fbb319546f94d64 253 PRINTS PR00721 Stomatin signature 171 192 1.0E-60 T 06-07-2017 IPR001972 Stomatin family GO:0016020 BWK49_RS11270 284c02ba27a4cea91fbb319546f94d64 253 PRINTS PR00721 Stomatin signature 196 219 1.0E-60 T 06-07-2017 IPR001972 Stomatin family GO:0016020 BWK49_RS11270 284c02ba27a4cea91fbb319546f94d64 253 PRINTS PR00721 Stomatin signature 152 170 1.0E-60 T 06-07-2017 IPR001972 Stomatin family GO:0016020 BWK49_RS11270 284c02ba27a4cea91fbb319546f94d64 253 PRINTS PR00721 Stomatin signature 73 94 1.0E-60 T 06-07-2017 IPR001972 Stomatin family GO:0016020 BWK49_RS11270 284c02ba27a4cea91fbb319546f94d64 253 PRINTS PR00721 Stomatin signature 108 125 1.0E-60 T 06-07-2017 IPR001972 Stomatin family GO:0016020 BWK49_RS11270 284c02ba27a4cea91fbb319546f94d64 253 PRINTS PR00721 Stomatin signature 26 48 1.0E-60 T 06-07-2017 IPR001972 Stomatin family GO:0016020 BWK49_RS11270 284c02ba27a4cea91fbb319546f94d64 253 SUPERFAMILY SSF117892 50 183 8.37E-40 T 06-07-2017 IPR001107 Band 7 domain BWK49_RS11270 284c02ba27a4cea91fbb319546f94d64 253 Pfam PF01145 SPFH domain / Band 7 family 23 192 5.0E-36 T 06-07-2017 IPR001107 Band 7 domain BWK49_RS11270 284c02ba27a4cea91fbb319546f94d64 253 SMART SM00244 19 176 3.4E-50 T 06-07-2017 IPR001107 Band 7 domain BWK49_RS04910 2781e2ed0ea886d0c0b69f7bc0be9995 237 Pfam PF02405 Permease MlaE 19 228 6.7E-56 T 06-07-2017 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 BWK49_RS20970 469f925eb27f9609c1ca45a292d52f5d 308 Gene3D G3DSA:3.40.50.300 59 292 1.2E-19 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS20970 469f925eb27f9609c1ca45a292d52f5d 308 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 59 219 5.6E-10 T 06-07-2017 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain BWK49_RS20970 469f925eb27f9609c1ca45a292d52f5d 308 SUPERFAMILY SSF52540 59 292 4.79E-22 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS09560 2504ecadc1880f752665189c458a8a18 141 SUPERFAMILY SSF54427 1 138 1.72E-16 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS09560 2504ecadc1880f752665189c458a8a18 141 Pfam PF13577 SnoaL-like domain 16 127 2.8E-6 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain BWK49_RS09560 2504ecadc1880f752665189c458a8a18 141 Gene3D G3DSA:3.10.450.50 9 130 2.2E-8 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS01925 9e1c9182ccd3def2d21132163e3c95af 114 Gene3D G3DSA:3.30.420.10 10 94 1.2E-9 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS01925 9e1c9182ccd3def2d21132163e3c95af 114 SUPERFAMILY SSF53098 9 97 4.93E-12 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS01925 9e1c9182ccd3def2d21132163e3c95af 114 Pfam PF13683 Integrase core domain 27 93 2.2E-10 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 BWK49_RS14335 a5424cef06e24596c314701eb5102d3e 408 Pfam PF03734 L,D-transpeptidase catalytic domain 245 376 2.6E-14 T 06-07-2017 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 BWK49_RS14335 a5424cef06e24596c314701eb5102d3e 408 Gene3D G3DSA:2.40.440.10 247 377 2.4E-13 T 06-07-2017 BWK49_RS14335 a5424cef06e24596c314701eb5102d3e 408 SUPERFAMILY SSF141523 245 376 7.59E-20 T 06-07-2017 BWK49_RS17960 6769dbec03d1b50468cc2ce5a93d7370 134 Gene3D G3DSA:2.60.120.10 15 114 5.5E-12 T 06-07-2017 IPR014710 RmlC-like jelly roll fold BWK49_RS17960 6769dbec03d1b50468cc2ce5a93d7370 134 SUPERFAMILY SSF51182 18 108 1.74E-10 T 06-07-2017 IPR011051 RmlC-like cupin domain BWK49_RS12055 9ae4567f5100352901df1e9b616c1a0c 122 Pfam PF13564 DoxX-like family 7 109 4.0E-17 T 06-07-2017 IPR032808 DoxX family BWK49_RS00805 ef1e7df52275412ce0c2bba4ea608a38 345 TIGRFAM TIGR03559 F420_Rv3520c: probable F420-dependent oxidoreductase, Rv3520c family 2 324 3.0E-159 T 06-07-2017 IPR019951 F420-dependent oxidoreductase-predicted, Rv3520c BWK49_RS00805 ef1e7df52275412ce0c2bba4ea608a38 345 SUPERFAMILY SSF51679 1 345 8.24E-64 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS00805 ef1e7df52275412ce0c2bba4ea608a38 345 Gene3D G3DSA:3.20.20.30 1 345 5.0E-69 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS00805 ef1e7df52275412ce0c2bba4ea608a38 345 Pfam PF00296 Luciferase-like monooxygenase 9 320 4.5E-71 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS24040 4320fc82c2ca1c0c75db092e54dade09 279 Pfam PF00296 Luciferase-like monooxygenase 23 117 1.4E-12 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS24040 4320fc82c2ca1c0c75db092e54dade09 279 TIGRFAM TIGR03620 F420_MSMEG_4141: probable F420-dependent oxidoreductase, MSMEG_4141 family 22 276 1.2E-113 T 06-07-2017 IPR019922 Luciferase-like, F420-dependent oxidoreductase, MSMEG4141, predicted BWK49_RS24040 4320fc82c2ca1c0c75db092e54dade09 279 Gene3D G3DSA:3.20.20.30 23 120 4.5E-13 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS24040 4320fc82c2ca1c0c75db092e54dade09 279 Gene3D G3DSA:3.20.20.30 131 274 4.9E-13 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS24040 4320fc82c2ca1c0c75db092e54dade09 279 SUPERFAMILY SSF51679 21 276 6.62E-38 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS15335 56724cc15e9ce063ce058072d0f65e5d 142 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 3 140 1.2E-18 T 06-07-2017 IPR019587 Polyketide cyclase/dehydrase BWK49_RS15335 56724cc15e9ce063ce058072d0f65e5d 142 Gene3D G3DSA:3.30.530.20 4 139 1.7E-14 T 06-07-2017 IPR023393 START-like domain BWK49_RS15335 56724cc15e9ce063ce058072d0f65e5d 142 SUPERFAMILY SSF55961 3 140 1.45E-20 T 06-07-2017 BWK49_RS28355 8a49e94fd29c322b7638f81c54b7640c 331 SUPERFAMILY SSF110849 55 162 3.66E-31 T 06-07-2017 IPR003115 ParB/Sulfiredoxin BWK49_RS28355 8a49e94fd29c322b7638f81c54b7640c 331 SMART SM00470 65 159 2.3E-36 T 06-07-2017 IPR003115 ParB/Sulfiredoxin BWK49_RS28355 8a49e94fd29c322b7638f81c54b7640c 331 SUPERFAMILY SSF109709 151 260 1.44E-31 T 06-07-2017 BWK49_RS28355 8a49e94fd29c322b7638f81c54b7640c 331 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 61 245 3.6E-65 T 06-07-2017 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 BWK49_RS28355 8a49e94fd29c322b7638f81c54b7640c 331 Gene3D G3DSA:3.90.1530.10 59 165 6.2E-38 T 06-07-2017 BWK49_RS28355 8a49e94fd29c322b7638f81c54b7640c 331 Pfam PF02195 ParB-like nuclease domain 66 159 2.6E-25 T 06-07-2017 IPR003115 ParB/Sulfiredoxin BWK49_RS23025 e310dd16439294f4ccce1b3f72d620fd 181 SUPERFAMILY SSF55811 38 163 3.11E-23 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 BWK49_RS23025 e310dd16439294f4ccce1b3f72d620fd 181 Gene3D G3DSA:3.90.79.10 47 164 2.0E-19 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 BWK49_RS23025 e310dd16439294f4ccce1b3f72d620fd 181 Pfam PF00293 NUDIX domain 47 162 1.4E-11 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 BWK49_RS25605 62079aa258bbb30b183c2358612c9697 133 Gene3D G3DSA:2.30.110.10 11 97 4.9E-4 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 BWK49_RS25605 62079aa258bbb30b183c2358612c9697 133 ProDom PD086639 PYRIDOXAMINE 5'-PHOSPHATE MB0449C OXIDASE-RELATED RV0441C/MT0457 19 113 3.0E-38 T 06-07-2017 IPR020145 Uncharacterised protein family, MT0457 BWK49_RS20210 33e5982e9709642f716035d27fd84890 171 Pfam PF01551 Peptidase family M23 49 135 8.6E-15 T 06-07-2017 IPR016047 Peptidase M23 BWK49_RS20210 33e5982e9709642f716035d27fd84890 171 Gene3D G3DSA:2.70.70.10 15 152 5.1E-26 T 06-07-2017 BWK49_RS20210 33e5982e9709642f716035d27fd84890 171 SUPERFAMILY SSF51261 22 151 8.89E-17 T 06-07-2017 IPR011055 Duplicated hybrid motif BWK49_RS19795 0cddceed71f05750f9839a46568dd333 153 SUPERFAMILY SSF55961 6 152 1.06E-19 T 06-07-2017 BWK49_RS19795 0cddceed71f05750f9839a46568dd333 153 Gene3D G3DSA:3.30.530.20 2 152 1.7E-12 T 06-07-2017 IPR023393 START-like domain BWK49_RS19795 0cddceed71f05750f9839a46568dd333 153 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 5 151 1.0E-17 T 06-07-2017 IPR019587 Polyketide cyclase/dehydrase BWK49_RS17370 a23379522adb58afd266c27331b21c10 221 Pfam PF10821 Protein of unknown function (DUF2567) 33 197 2.8E-71 T 06-07-2017 IPR021213 Protein of unknown function DUF2567 BWK49_RS27865 589791ac598c4806c5175d79b1424a87 1610 Pfam PF00689 Cation transporting ATPase, C-terminus 1422 1591 3.7E-13 T 06-07-2017 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 BWK49_RS27865 589791ac598c4806c5175d79b1424a87 1610 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 1334 1350 9.0E-16 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 BWK49_RS27865 589791ac598c4806c5175d79b1424a87 1610 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 1366 1391 9.0E-16 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 BWK49_RS27865 589791ac598c4806c5175d79b1424a87 1610 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 1186 1204 9.0E-16 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 BWK49_RS27865 589791ac598c4806c5175d79b1424a87 1610 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 1306 1322 9.0E-16 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 BWK49_RS27865 589791ac598c4806c5175d79b1424a87 1610 Pfam PF00122 E1-E2 ATPase 794 1039 7.4E-42 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 BWK49_RS27865 589791ac598c4806c5175d79b1424a87 1610 Pfam PF00702 haloacid dehalogenase-like hydrolase 1044 1348 2.4E-24 T 06-07-2017 BWK49_RS27865 589791ac598c4806c5175d79b1424a87 1610 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 1050 1056 - T 06-07-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 BWK49_RS27865 589791ac598c4806c5175d79b1424a87 1610 Gene3D G3DSA:1.20.1110.10 1303 1588 2.7E-59 T 06-07-2017 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 BWK49_RS27865 589791ac598c4806c5175d79b1424a87 1610 Gene3D G3DSA:1.20.1110.10 768 823 2.7E-59 T 06-07-2017 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 BWK49_RS27865 589791ac598c4806c5175d79b1424a87 1610 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 889 903 1.1E-26 T 06-07-2017 BWK49_RS27865 589791ac598c4806c5175d79b1424a87 1610 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 1358 1370 1.1E-26 T 06-07-2017 BWK49_RS27865 589791ac598c4806c5175d79b1424a87 1610 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 1233 1244 1.1E-26 T 06-07-2017 BWK49_RS27865 589791ac598c4806c5175d79b1424a87 1610 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 1255 1265 1.1E-26 T 06-07-2017 BWK49_RS27865 589791ac598c4806c5175d79b1424a87 1610 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 1334 1353 1.1E-26 T 06-07-2017 BWK49_RS27865 589791ac598c4806c5175d79b1424a87 1610 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 1048 1062 1.1E-26 T 06-07-2017 BWK49_RS27865 589791ac598c4806c5175d79b1424a87 1610 SUPERFAMILY SSF56784 1046 1066 3.77E-44 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS27865 589791ac598c4806c5175d79b1424a87 1610 SUPERFAMILY SSF56784 1183 1440 3.77E-44 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS27865 589791ac598c4806c5175d79b1424a87 1610 SUPERFAMILY SSF81665 767 826 7.45E-50 T 06-07-2017 BWK49_RS27865 589791ac598c4806c5175d79b1424a87 1610 SUPERFAMILY SSF81665 1384 1593 7.45E-50 T 06-07-2017 BWK49_RS27865 589791ac598c4806c5175d79b1424a87 1610 SUPERFAMILY SSF81665 949 1042 7.45E-50 T 06-07-2017 BWK49_RS27865 589791ac598c4806c5175d79b1424a87 1610 SUPERFAMILY SSF81653 852 948 2.35E-20 T 06-07-2017 BWK49_RS27865 589791ac598c4806c5175d79b1424a87 1610 Gene3D G3DSA:2.70.150.10 852 949 4.3E-23 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 BWK49_RS27865 589791ac598c4806c5175d79b1424a87 1610 Gene3D G3DSA:3.40.1110.10 1038 1239 5.6E-27 T 06-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 BWK49_RS27865 589791ac598c4806c5175d79b1424a87 1610 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 1303 1415 3.9E-27 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 BWK49_RS27865 589791ac598c4806c5175d79b1424a87 1610 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 851 1069 1.6E-29 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 BWK49_RS10640 f36a78b3fc0a05360dfb908a388f5f8a 264 Pfam PF06912 Protein of unknown function (DUF1275) 22 212 1.3E-23 T 06-07-2017 IPR010699 Protein of unknown function DUF1275 BWK49_RS13335 651683e158659a9129cfa008b426e176 280 Pfam PF02405 Permease MlaE 59 270 1.7E-53 T 06-07-2017 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 BWK49_RS21190 10d86c952d9e75f68be34dd073edd4d4 110 Pfam PF11338 Protein of unknown function (DUF3140) 12 101 6.8E-39 T 06-07-2017 IPR021487 Protein of unknown function DUF3140 BWK49_RS18295 a2da9efb68be796b5f62b609ea275bd3 464 Pfam PF02720 Domain of unknown function (DUF222) 40 364 7.7E-95 T 06-07-2017 IPR003870 Domain of unknown function DUF222 BWK49_RS18295 a2da9efb68be796b5f62b609ea275bd3 464 ProDom PD008243 RV1792C/MT1741/MB1728C RV1945/MT1995 MB1980 MB0098C RV3466/MT3572 VERY RV1128C/MT1160 RV1148C/MT1183 MB1159C RV0095C 23 95 4.0E-17 T 06-07-2017 BWK49_RS18295 a2da9efb68be796b5f62b609ea275bd3 464 SMART SM00507 355 407 6.6E-5 T 06-07-2017 IPR003615 HNH nuclease BWK49_RS02645 6a518de02679585bd52048cd81ce1ae9 328 TIGRFAM TIGR03557 F420_G6P_family: F420-dependent oxidoreductase, G6PDH family 4 325 1.5E-156 T 06-07-2017 IPR019945 F420-dependent glucose-6-phosphate dehydrogenase-related BWK49_RS02645 6a518de02679585bd52048cd81ce1ae9 328 Gene3D G3DSA:3.20.20.30 2 324 2.8E-65 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS02645 6a518de02679585bd52048cd81ce1ae9 328 Pfam PF00296 Luciferase-like monooxygenase 3 296 1.3E-48 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS02645 6a518de02679585bd52048cd81ce1ae9 328 SUPERFAMILY SSF51679 2 323 8.54E-63 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS07460 5912dd305dbefb40d7caa72862c9f2f3 218 Pfam PF10738 Probable lipoprotein LpqN 49 216 6.6E-61 T 06-07-2017 IPR019674 Lipoprotein LpqT, predicted BWK49_RS09435 dbfef6516e87f3e99baea1c6e15524d5 273 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4 193 0.0089 T 06-07-2017 BWK49_RS09435 dbfef6516e87f3e99baea1c6e15524d5 273 SUPERFAMILY SSF51735 2 249 3.98E-53 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS09435 dbfef6516e87f3e99baea1c6e15524d5 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 1.2E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS09435 dbfef6516e87f3e99baea1c6e15524d5 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 1.2E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS09435 dbfef6516e87f3e99baea1c6e15524d5 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 1.2E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS09435 dbfef6516e87f3e99baea1c6e15524d5 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 1.2E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS09435 dbfef6516e87f3e99baea1c6e15524d5 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 118 134 1.2E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS09435 dbfef6516e87f3e99baea1c6e15524d5 273 Pfam PF00106 short chain dehydrogenase 5 198 3.9E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS09435 dbfef6516e87f3e99baea1c6e15524d5 273 Gene3D G3DSA:3.40.50.720 3 243 1.7E-53 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS27070 e3177160ab1fe41e30047c50d42d6805 380 Pfam PF01594 Domain of unknown function DUF20 22 346 1.1E-73 T 06-07-2017 IPR002549 Transmembrane protein TqsA-like BWK49_RS05950 aa365df2f1eae10f5253857599fdec6f 255 Gene3D G3DSA:3.40.50.720 1 204 1.3E-29 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS05950 aa365df2f1eae10f5253857599fdec6f 255 Pfam PF13460 NAD(P)H-binding 7 172 9.7E-11 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS05950 aa365df2f1eae10f5253857599fdec6f 255 SUPERFAMILY SSF51735 1 253 4.4E-35 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS29040 303ecad80642f436411441891acae6dc 473 SUPERFAMILY SSF52540 33 381 2.62E-13 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS29040 303ecad80642f436411441891acae6dc 473 Gene3D G3DSA:3.40.50.300 261 360 2.2E-7 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS29040 303ecad80642f436411441891acae6dc 473 Gene3D G3DSA:3.40.50.300 74 149 2.2E-7 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS29040 303ecad80642f436411441891acae6dc 473 Pfam PF12846 AAA-like domain 81 363 1.5E-18 T 06-07-2017 BWK49_RS11505 061f1da8274969db3b2c2a6e1c3bec62 408 Pfam PF00823 PPE family 8 162 2.7E-59 T 06-07-2017 IPR000030 PPE family BWK49_RS11505 061f1da8274969db3b2c2a6e1c3bec62 408 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 321 406 8.4E-12 T 06-07-2017 IPR022171 PPE family, C-terminal BWK49_RS11505 061f1da8274969db3b2c2a6e1c3bec62 408 SUPERFAMILY SSF140459 5 174 1.49E-60 T 06-07-2017 BWK49_RS11095 d7682ee97ae07937f934d7f7f3c0e9c6 280 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 42 261 3.0E-36 T 06-07-2017 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 BWK49_RS11095 d7682ee97ae07937f934d7f7f3c0e9c6 280 Gene3D G3DSA:3.20.20.60 18 273 1.7E-64 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 BWK49_RS11095 d7682ee97ae07937f934d7f7f3c0e9c6 280 SUPERFAMILY SSF51621 18 272 1.49E-65 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 BWK49_RS20785 b79f0c3b5979b5ec80097bc28974e2dd 273 Pfam PF00106 short chain dehydrogenase 8 210 6.2E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS20785 b79f0c3b5979b5ec80097bc28974e2dd 273 TIGRFAM TIGR03971 SDR_subfam_1: SDR family mycofactocin-dependent oxidoreductase 5 272 1.7E-98 T 06-07-2017 IPR023985 Mycofactocin-dependent oxidoreductase BWK49_RS20785 b79f0c3b5979b5ec80097bc28974e2dd 273 SUPERFAMILY SSF51735 3 273 1.65E-56 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS20785 b79f0c3b5979b5ec80097bc28974e2dd 273 Gene3D G3DSA:3.40.50.720 2 271 1.8E-61 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS20785 b79f0c3b5979b5ec80097bc28974e2dd 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 94 105 5.0E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS20785 b79f0c3b5979b5ec80097bc28974e2dd 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 194 211 5.0E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS20785 b79f0c3b5979b5ec80097bc28974e2dd 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 234 254 5.0E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS20785 b79f0c3b5979b5ec80097bc28974e2dd 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 5.0E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS20785 b79f0c3b5979b5ec80097bc28974e2dd 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 192 5.0E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS20785 b79f0c3b5979b5ec80097bc28974e2dd 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 142 158 5.0E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS20785 b79f0c3b5979b5ec80097bc28974e2dd 273 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 94 105 9.4E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS20785 b79f0c3b5979b5ec80097bc28974e2dd 273 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 173 192 9.4E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS20785 b79f0c3b5979b5ec80097bc28974e2dd 273 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 156 9.4E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS03190 dd3ab89170bc42661c0b11bffb1a7c98 310 SMART SM00967 70 146 1.7E-15 T 06-07-2017 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 BWK49_RS03190 dd3ab89170bc42661c0b11bffb1a7c98 310 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 68 308 6.8E-61 T 06-07-2017 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 BWK49_RS03190 dd3ab89170bc42661c0b11bffb1a7c98 310 Pfam PF00588 SpoU rRNA Methylase family 162 301 5.3E-36 T 06-07-2017 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 BWK49_RS03190 dd3ab89170bc42661c0b11bffb1a7c98 310 Gene3D G3DSA:3.30.1330.30 64 142 9.5E-20 T 06-07-2017 IPR029064 50S ribosomal protein L30e-like BWK49_RS03190 dd3ab89170bc42661c0b11bffb1a7c98 310 SUPERFAMILY SSF75217 134 309 1.24E-44 T 06-07-2017 IPR029028 Alpha/beta knot methyltransferases BWK49_RS03190 dd3ab89170bc42661c0b11bffb1a7c98 310 SUPERFAMILY SSF55315 65 143 1.77E-16 T 06-07-2017 IPR029064 50S ribosomal protein L30e-like BWK49_RS03190 dd3ab89170bc42661c0b11bffb1a7c98 310 Gene3D G3DSA:3.40.1280.10 159 309 3.7E-51 T 06-07-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal BWK49_RS03190 dd3ab89170bc42661c0b11bffb1a7c98 310 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 71 145 7.8E-18 T 06-07-2017 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 BWK49_RS04440 b9fac5170f41dae987a300938bd3ba52 273 Pfam PF10935 Protein of unknown function (DUF2637) 89 147 5.7E-8 T 06-07-2017 IPR021235 Protein of unknown function DUF2637 BWK49_RS01325 685417966c07b7fbffaa97d2b5eb45ab 194 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 21 190 1.2E-31 T 06-07-2017 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type BWK49_RS01325 685417966c07b7fbffaa97d2b5eb45ab 194 SUPERFAMILY SSF109854 10 137 4.58E-12 T 06-07-2017 BWK49_RS01325 685417966c07b7fbffaa97d2b5eb45ab 194 TIGRFAM TIGR03086 TIGR03086: TIGR03086 family protein 21 190 7.0E-50 T 06-07-2017 IPR017520 Conserved hypothetical protein CHP03086 BWK49_RS01325 685417966c07b7fbffaa97d2b5eb45ab 194 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 27 99 2.0E-7 T 06-07-2017 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 BWK49_RS25205 96a434fe4b4a89fa9507ba6b8447e801 381 Gene3D G3DSA:3.20.20.30 4 258 1.9E-92 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS25205 96a434fe4b4a89fa9507ba6b8447e801 381 Gene3D G3DSA:3.20.20.30 292 362 1.9E-92 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS25205 96a434fe4b4a89fa9507ba6b8447e801 381 Pfam PF00296 Luciferase-like monooxygenase 5 331 4.6E-77 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS25205 96a434fe4b4a89fa9507ba6b8447e801 381 SUPERFAMILY SSF51679 4 363 8.98E-84 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS12765 2846fa305eed25cd59388758c70b048d 250 ProDom PD037701 MEMBRANE INTEGRAL TRANSMEMBRANE RV2219/MT2276 NARROWLY PROBABLE PRECURSOR SIGNAL MLCB22.21 32 239 2.0E-90 T 06-07-2017 BWK49_RS12765 2846fa305eed25cd59388758c70b048d 250 Pfam PF13829 Domain of unknown function (DUF4191) 23 241 1.2E-83 T 06-07-2017 IPR025445 Protein of unknown function DUF4191 BWK49_RS13000 9c341729da531ed29478a03341926ef7 515 TIGRFAM TIGR03459 crt_membr: carotene biosynthesis associated membrane protein 37 496 1.8E-196 T 06-07-2017 IPR017822 Carotene biosynthesis-associated membrane protein, type-1 BWK49_RS12305 8397c039389ff2a01fc3c56275f10aa0 521 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 18 41 - T 06-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 BWK49_RS12305 8397c039389ff2a01fc3c56275f10aa0 521 Gene3D G3DSA:3.30.200.20 9 108 2.4E-23 T 06-07-2017 BWK49_RS12305 8397c039389ff2a01fc3c56275f10aa0 521 Gene3D G3DSA:1.10.510.10 109 280 4.1E-41 T 06-07-2017 BWK49_RS12305 8397c039389ff2a01fc3c56275f10aa0 521 SMART SM00220 12 268 2.6E-50 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 BWK49_RS12305 8397c039389ff2a01fc3c56275f10aa0 521 SUPERFAMILY SSF56112 7 269 4.72E-68 T 06-07-2017 IPR011009 Protein kinase-like domain BWK49_RS12305 8397c039389ff2a01fc3c56275f10aa0 521 Pfam PF00069 Protein kinase domain 12 260 2.1E-46 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 BWK49_RS12305 8397c039389ff2a01fc3c56275f10aa0 521 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 130 142 - T 06-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 BWK49_RS15790 b88b3cc51a06eba7e048c826c312d6c2 208 SMART SM00886 99 196 2.5E-19 T 06-07-2017 IPR013097 Stress responsive alpha-beta barrel BWK49_RS15790 b88b3cc51a06eba7e048c826c312d6c2 208 Pfam PF07876 Stress responsive A/B Barrel Domain 99 195 6.6E-15 T 06-07-2017 IPR013097 Stress responsive alpha-beta barrel BWK49_RS15790 b88b3cc51a06eba7e048c826c312d6c2 208 SUPERFAMILY SSF54909 97 203 5.5E-19 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel BWK49_RS15790 b88b3cc51a06eba7e048c826c312d6c2 208 Gene3D G3DSA:3.30.70.900 97 195 2.7E-10 T 06-07-2017 BWK49_RS01465 63855a7414465ec51269b0cf162df53f 261 Pfam PF02405 Permease MlaE 44 254 1.8E-58 T 06-07-2017 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 BWK49_RS20415 b98f2143df4b8d152c9a381fdb8345b7 245 Gene3D G3DSA:1.20.5.620 95 146 1.2E-4 T 06-07-2017 IPR028987 F-type ATP synthase subunit B-like, membrane domain BWK49_RS01850 7b9968ae28e9cf68503174507aa81b01 486 Gene3D G3DSA:3.40.309.10 255 438 4.2E-55 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 BWK49_RS01850 7b9968ae28e9cf68503174507aa81b01 486 Gene3D G3DSA:3.40.605.10 4 254 6.6E-81 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 BWK49_RS01850 7b9968ae28e9cf68503174507aa81b01 486 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 243 250 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 BWK49_RS01850 7b9968ae28e9cf68503174507aa81b01 486 Pfam PF00171 Aldehyde dehydrogenase family 13 474 1.9E-141 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 BWK49_RS01850 7b9968ae28e9cf68503174507aa81b01 486 SUPERFAMILY SSF53720 2 475 1.57E-140 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 BWK49_RS21775 fb53b0e11b57ecdb5ad498d8c65c9a57 733 Pfam PF01757 Acyltransferase family 33 350 7.3E-20 T 06-07-2017 IPR002656 Acyltransferase 3 GO:0016747 BWK49_RS04400 17396dfe3763428a72847fc90c71ee53 493 Pfam PF00823 PPE family 5 158 3.9E-27 T 06-07-2017 IPR000030 PPE family BWK49_RS04400 17396dfe3763428a72847fc90c71ee53 493 SUPERFAMILY SSF140459 1 167 1.26E-28 T 06-07-2017 BWK49_RS26275 0e813763b97dda6e84d42e2cd7a809c0 114 Pfam PF05305 Protein of unknown function (DUF732) 21 113 3.1E-12 T 06-07-2017 IPR007969 Domain of unknown function DUF732 BWK49_RS24920 5d0303ee97621f6841933535dd42a03e 317 Pfam PF10118 Predicted metal-dependent hydrolase 7 194 1.6E-32 T 06-07-2017 IPR016516 Uncharacterised conserved protein UCP07580 BWK49_RS25570 bfb864135cb4f5d742dd219b39b73aee 228 Gene3D G3DSA:1.10.357.10 15 193 5.4E-18 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS25570 bfb864135cb4f5d742dd219b39b73aee 228 Pfam PF00440 Bacterial regulatory proteins, tetR family 28 72 1.5E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS25570 bfb864135cb4f5d742dd219b39b73aee 228 SUPERFAMILY SSF46689 16 87 1.95E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS01645 0e61b62ca7e06e4b2cbda300d4f92cc9 314 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 62 294 2.1E-20 T 06-07-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 BWK49_RS01645 0e61b62ca7e06e4b2cbda300d4f92cc9 314 Gene3D G3DSA:3.40.830.10 2 313 7.0E-58 T 06-07-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 BWK49_RS01645 0e61b62ca7e06e4b2cbda300d4f92cc9 314 SUPERFAMILY SSF53213 3 24 3.92E-43 T 06-07-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 BWK49_RS01645 0e61b62ca7e06e4b2cbda300d4f92cc9 314 SUPERFAMILY SSF53213 56 313 3.92E-43 T 06-07-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 BWK49_RS03125 6dfedaf1dfe9d10243e19d4225b53165 454 SUPERFAMILY SSF56601 343 450 2.07E-36 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like BWK49_RS03125 6dfedaf1dfe9d10243e19d4225b53165 454 SUPERFAMILY SSF56601 80 293 2.07E-36 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like BWK49_RS03125 6dfedaf1dfe9d10243e19d4225b53165 454 Gene3D G3DSA:3.40.710.10 347 449 1.3E-34 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like BWK49_RS03125 6dfedaf1dfe9d10243e19d4225b53165 454 Gene3D G3DSA:3.40.710.10 156 301 1.3E-34 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like BWK49_RS03125 6dfedaf1dfe9d10243e19d4225b53165 454 Pfam PF13354 Beta-lactamase enzyme family 184 307 1.4E-21 T 06-07-2017 BWK49_RS14210 6f12a4939984df4bea75bfe40c117265 268 SUPERFAMILY SSF53335 3 189 2.28E-30 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS14210 6f12a4939984df4bea75bfe40c117265 268 Gene3D G3DSA:3.40.50.150 3 203 2.0E-27 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS14210 6f12a4939984df4bea75bfe40c117265 268 Pfam PF08241 Methyltransferase domain 34 122 1.4E-17 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 BWK49_RS14210 6f12a4939984df4bea75bfe40c117265 268 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 33 60 - T 06-07-2017 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 BWK49_RS18780 2073d37d919a3a372042d784c1ddcb02 180 Gene3D G3DSA:3.40.50.2020 12 178 3.9E-51 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like BWK49_RS18780 2073d37d919a3a372042d784c1ddcb02 180 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 14 180 31.981 T 06-07-2017 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|Reactome: R-HSA-74217 BWK49_RS18780 2073d37d919a3a372042d784c1ddcb02 180 SUPERFAMILY SSF53271 19 173 3.93E-39 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like BWK49_RS18780 2073d37d919a3a372042d784c1ddcb02 180 Pfam PF00156 Phosphoribosyl transferase domain 43 159 1.2E-16 T 06-07-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 BWK49_RS00145 b13b44bceb683f2ee386db806912b1f3 119 Gene3D G3DSA:3.10.450.50 6 102 3.4E-18 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS00145 b13b44bceb683f2ee386db806912b1f3 119 SUPERFAMILY SSF54427 4 108 1.18E-18 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS00145 b13b44bceb683f2ee386db806912b1f3 119 Pfam PF12680 SnoaL-like domain 11 89 1.7E-13 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain BWK49_RS06600 78271e542f04b24cfa857f05db16f6d7 135 PIRSF PIRSF028777 1 129 3.8E-49 T 06-07-2017 IPR031308 Uncharacterised conserved protein UCP028777 BWK49_RS06600 78271e542f04b24cfa857f05db16f6d7 135 Pfam PF03733 Inner membrane component domain 68 118 1.0E-16 T 06-07-2017 IPR005185 Inner membrane component domain BWK49_RS06600 78271e542f04b24cfa857f05db16f6d7 135 Pfam PF03733 Inner membrane component domain 4 54 5.6E-17 T 06-07-2017 IPR005185 Inner membrane component domain BWK49_RS13855 7362d2a6f586cf413342959c6b161acc 325 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 227 8.2E-29 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 BWK49_RS13855 7362d2a6f586cf413342959c6b161acc 325 Gene3D G3DSA:3.40.50.720 6 317 1.4E-53 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS13855 7362d2a6f586cf413342959c6b161acc 325 SUPERFAMILY SSF51735 6 324 1.09E-61 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS04820 9256a45f00a79f978108c6eb09ec8005 268 PIRSF PIRSF007580 1 262 4.6E-65 T 06-07-2017 IPR016516 Uncharacterised conserved protein UCP07580 BWK49_RS04820 9256a45f00a79f978108c6eb09ec8005 268 Pfam PF10118 Predicted metal-dependent hydrolase 2 244 1.3E-69 T 06-07-2017 IPR016516 Uncharacterised conserved protein UCP07580 BWK49_RS13970 f4c822d09b3792db984dd5efba5dbc51 690 SUPERFAMILY SSF53098 254 321 1.19E-13 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS13970 f4c822d09b3792db984dd5efba5dbc51 690 SUPERFAMILY SSF53098 357 465 1.19E-13 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS13970 f4c822d09b3792db984dd5efba5dbc51 690 Gene3D G3DSA:3.30.420.10 258 327 3.3E-19 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS13970 f4c822d09b3792db984dd5efba5dbc51 690 Gene3D G3DSA:3.30.420.10 361 464 3.3E-19 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS13970 f4c822d09b3792db984dd5efba5dbc51 690 Pfam PF09299 Mu transposase, C-terminal 501 567 2.1E-9 T 06-07-2017 IPR015378 Transposase-like, Mu, C-terminal BWK49_RS13970 f4c822d09b3792db984dd5efba5dbc51 690 Pfam PF00665 Integrase core domain 257 412 9.7E-10 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 BWK49_RS23050 17df724fce0cc2038d755c17fecce59b 228 SUPERFAMILY SSF56801 8 226 8.24E-17 T 06-07-2017 BWK49_RS23050 17df724fce0cc2038d755c17fecce59b 228 Gene3D G3DSA:3.40.50.980 28 81 7.5E-5 T 06-07-2017 BWK49_RS23050 17df724fce0cc2038d755c17fecce59b 228 TIGRFAM TIGR03089 TIGR03089: TIGR03089 family protein 1 225 8.0E-69 T 06-07-2017 IPR017523 Conserved hypothetical protein CHP03089 BWK49_RS23050 17df724fce0cc2038d755c17fecce59b 228 Pfam PF00501 AMP-binding enzyme 19 81 2.9E-5 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS26720 d615fed4c87a109f0591783c7627506e 417 SUPERFAMILY SSF81340 14 404 1.29E-54 T 06-07-2017 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 BWK49_RS26720 d615fed4c87a109f0591783c7627506e 417 Gene3D G3DSA:1.10.3080.10 8 401 1.3E-35 T 06-07-2017 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 BWK49_RS26720 d615fed4c87a109f0591783c7627506e 417 Pfam PF00654 Voltage gated chloride channel 99 401 1.2E-42 T 06-07-2017 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 BWK49_RS26720 d615fed4c87a109f0591783c7627506e 417 PRINTS PR00762 Chloride channel signature 159 178 1.1E-6 T 06-07-2017 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 BWK49_RS26720 d615fed4c87a109f0591783c7627506e 417 PRINTS PR00762 Chloride channel signature 107 126 1.1E-6 T 06-07-2017 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 BWK49_RS07320 f0659efe44e06092729f3f6c03c33178 372 Gene3D G3DSA:3.40.50.720 1 131 9.6E-40 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS07320 f0659efe44e06092729f3f6c03c33178 372 SUPERFAMILY SSF51735 2 149 2.52E-44 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS07320 f0659efe44e06092729f3f6c03c33178 372 SUPERFAMILY SSF55347 127 313 9.48E-30 T 06-07-2017 BWK49_RS07320 f0659efe44e06092729f3f6c03c33178 372 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 2 120 4.0E-28 T 06-07-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 BWK49_RS07320 f0659efe44e06092729f3f6c03c33178 372 Gene3D G3DSA:3.30.360.10 132 333 1.3E-35 T 06-07-2017 BWK49_RS07320 f0659efe44e06092729f3f6c03c33178 372 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 135 228 7.0E-9 T 06-07-2017 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 BWK49_RS05860 67234195b0d92d31f42ef3b7dc16ff73 295 SUPERFAMILY SSF52540 2 287 4.4E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS05860 67234195b0d92d31f42ef3b7dc16ff73 295 Gene3D G3DSA:3.40.50.300 44 236 2.0E-49 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS05860 67234195b0d92d31f42ef3b7dc16ff73 295 TIGRFAM TIGR00750 lao: LAO/AO transport system ATPase 13 286 1.5E-73 T 06-07-2017 IPR005129 SIMIBI class G3E GTPase, ArgK/MeaB GO:0003924|GO:0005525 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 BWK49_RS05860 67234195b0d92d31f42ef3b7dc16ff73 295 Pfam PF03308 ArgK protein 20 251 4.3E-72 T 06-07-2017 BWK49_RS01030 bacfaa13be4aa781be15edd573d17abe 262 Gene3D G3DSA:3.20.180.10 168 247 1.7E-7 T 06-07-2017 IPR019595 Domain of unknown function DUF2470 BWK49_RS01030 bacfaa13be4aa781be15edd573d17abe 262 Pfam PF10615 Protein of unknown function (DUF2470) 175 245 1.4E-7 T 06-07-2017 IPR019595 Domain of unknown function DUF2470 BWK49_RS01030 bacfaa13be4aa781be15edd573d17abe 262 SUPERFAMILY SSF50475 11 256 3.66E-30 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 BWK49_RS03670 016f638cf176db016480489b3d0bb811 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 1.5E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS03670 016f638cf176db016480489b3d0bb811 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 1.5E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS03670 016f638cf176db016480489b3d0bb811 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 1.5E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS03670 016f638cf176db016480489b3d0bb811 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 4.8E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS03670 016f638cf176db016480489b3d0bb811 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 4.8E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS03670 016f638cf176db016480489b3d0bb811 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 225 245 4.8E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS03670 016f638cf176db016480489b3d0bb811 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 4.8E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS03670 016f638cf176db016480489b3d0bb811 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 4.8E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS03670 016f638cf176db016480489b3d0bb811 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 4.8E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS03670 016f638cf176db016480489b3d0bb811 263 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS03670 016f638cf176db016480489b3d0bb811 263 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 193 8.3E-4 T 06-07-2017 BWK49_RS03670 016f638cf176db016480489b3d0bb811 263 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 262 1.7E-50 T 06-07-2017 BWK49_RS03670 016f638cf176db016480489b3d0bb811 263 SUPERFAMILY SSF51735 1 262 1.34E-67 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS03670 016f638cf176db016480489b3d0bb811 263 Gene3D G3DSA:3.40.50.720 1 262 3.6E-70 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS14525 873c58e2bcf4a563a440aad4165ed5ba 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 254 3.2E-71 T 06-07-2017 BWK49_RS14525 873c58e2bcf4a563a440aad4165ed5ba 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 164 183 1.6E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS14525 873c58e2bcf4a563a440aad4165ed5ba 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 142 150 1.6E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS14525 873c58e2bcf4a563a440aad4165ed5ba 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 88 99 1.6E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS14525 873c58e2bcf4a563a440aad4165ed5ba 256 Gene3D G3DSA:3.40.50.720 5 254 7.7E-91 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS14525 873c58e2bcf4a563a440aad4165ed5ba 256 SUPERFAMILY SSF51735 7 255 5.64E-86 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS14525 873c58e2bcf4a563a440aad4165ed5ba 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 1.6E-43 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS14525 873c58e2bcf4a563a440aad4165ed5ba 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 1.6E-43 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS14525 873c58e2bcf4a563a440aad4165ed5ba 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 136 152 1.6E-43 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS14525 873c58e2bcf4a563a440aad4165ed5ba 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 1.6E-43 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS14525 873c58e2bcf4a563a440aad4165ed5ba 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 183 1.6E-43 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS14525 873c58e2bcf4a563a440aad4165ed5ba 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 185 202 1.6E-43 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS14525 873c58e2bcf4a563a440aad4165ed5ba 256 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 151 179 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS01235 75e18b3c673fb4ac28786872db3f2bb2 628 Pfam PF12249 Arabinofuranosyltransferase A C terminal 452 624 7.8E-72 T 06-07-2017 IPR020959 Arabinofuranosyltransferase AftA, C-terminal GO:0005886|GO:0016021|GO:0016757|GO:0044038 BWK49_RS01235 75e18b3c673fb4ac28786872db3f2bb2 628 Pfam PF12250 Arabinofuranosyltransferase N terminal 12 429 9.9E-160 T 06-07-2017 IPR020963 Arabinofuranosyltransferase AftA, N-terminal GO:0005886|GO:0016021|GO:0016757|GO:0044038 BWK49_RS15240 024c1047a63a7a5f70328d7d41be5697 94 SUPERFAMILY SSF140453 2 93 9.55E-18 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like BWK49_RS15240 024c1047a63a7a5f70328d7d41be5697 94 PIRSF PIRSF037656 1 94 6.9E-57 T 06-07-2017 IPR009416 Protein of unknown function DUF1066 BWK49_RS15240 024c1047a63a7a5f70328d7d41be5697 94 Gene3D G3DSA:1.10.287.1060 2 94 1.8E-14 T 06-07-2017 BWK49_RS15240 024c1047a63a7a5f70328d7d41be5697 94 Pfam PF06013 Proteins of 100 residues with WXG 3 87 4.8E-15 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like BWK49_RS15410 a3e419b9d301ab79a6b499701617ae2a 283 SUPERFAMILY SSF52096 5 260 2.93E-54 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS15410 a3e419b9d301ab79a6b499701617ae2a 283 Pfam PF00378 Enoyl-CoA hydratase/isomerase 15 235 1.1E-29 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 BWK49_RS15410 a3e419b9d301ab79a6b499701617ae2a 283 Gene3D G3DSA:3.90.226.10 4 245 1.9E-50 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS15410 a3e419b9d301ab79a6b499701617ae2a 283 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 112 132 - T 06-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 BWK49_RS20245 c2c527d08c288aa9b8033d441c89ab34 273 Gene3D G3DSA:3.40.140.10 137 272 1.8E-55 T 06-07-2017 BWK49_RS20245 c2c527d08c288aa9b8033d441c89ab34 273 SUPERFAMILY SSF53927 5 272 1.59E-78 T 06-07-2017 IPR016193 Cytidine deaminase-like GO:0003824 BWK49_RS20245 c2c527d08c288aa9b8033d441c89ab34 273 Gene3D G3DSA:3.10.20.10 28 120 1.8E-27 T 06-07-2017 BWK49_RS20245 c2c527d08c288aa9b8033d441c89ab34 273 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 22 272 1.0E-49 T 06-07-2017 IPR003786 Protein FdhD GO:0016783 BWK49_RS20245 c2c527d08c288aa9b8033d441c89ab34 273 Hamap MF_00187 Sulfurtransferase FdhD [fdhD]. 2 273 32.686 T 06-07-2017 IPR003786 Protein FdhD GO:0016783 BWK49_RS20245 c2c527d08c288aa9b8033d441c89ab34 273 PIRSF PIRSF015626 1 273 2.0E-87 T 06-07-2017 IPR003786 Protein FdhD GO:0016783 BWK49_RS20245 c2c527d08c288aa9b8033d441c89ab34 273 Pfam PF02634 FdhD/NarQ family 26 272 2.4E-83 T 06-07-2017 IPR003786 Protein FdhD GO:0016783 BWK49_RS08170 2b7e296bf9ad9d00b00aa3cbb00e10e1 771 Gene3D G3DSA:1.20.1640.10 138 335 5.8E-29 T 06-07-2017 BWK49_RS08170 2b7e296bf9ad9d00b00aa3cbb00e10e1 771 Gene3D G3DSA:1.20.1640.10 510 732 3.1E-33 T 06-07-2017 BWK49_RS08170 2b7e296bf9ad9d00b00aa3cbb00e10e1 771 SUPERFAMILY SSF82866 119 334 3.01E-28 T 06-07-2017 BWK49_RS08170 2b7e296bf9ad9d00b00aa3cbb00e10e1 771 Pfam PF03176 MMPL family 44 373 4.3E-46 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 BWK49_RS08170 2b7e296bf9ad9d00b00aa3cbb00e10e1 771 Pfam PF03176 MMPL family 499 731 3.0E-26 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 BWK49_RS08170 2b7e296bf9ad9d00b00aa3cbb00e10e1 771 SUPERFAMILY SSF82866 502 728 1.06E-27 T 06-07-2017 BWK49_RS07205 0d862969d35b7f4ff8638b1083b69eaf 338 Gene3D G3DSA:3.30.230.10 4 196 9.3E-27 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup BWK49_RS07205 0d862969d35b7f4ff8638b1083b69eaf 338 Gene3D G3DSA:3.30.70.890 197 330 6.6E-17 T 06-07-2017 IPR013750 GHMP kinase, C-terminal domain BWK49_RS07205 0d862969d35b7f4ff8638b1083b69eaf 338 SUPERFAMILY SSF55060 191 336 2.47E-28 T 06-07-2017 IPR013750 GHMP kinase, C-terminal domain BWK49_RS07205 0d862969d35b7f4ff8638b1083b69eaf 338 Pfam PF08544 GHMP kinases C terminal 239 316 9.7E-10 T 06-07-2017 IPR013750 GHMP kinase, C-terminal domain BWK49_RS07205 0d862969d35b7f4ff8638b1083b69eaf 338 PRINTS PR00960 LmbP protein signature 10 25 6.4E-40 T 06-07-2017 IPR001174 Galactokinase/homoserine kinase GO:0005524|GO:0008152|GO:0016301 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.1.168|MetaCyc: PWY-6478 BWK49_RS07205 0d862969d35b7f4ff8638b1083b69eaf 338 PRINTS PR00960 LmbP protein signature 282 301 6.4E-40 T 06-07-2017 IPR001174 Galactokinase/homoserine kinase GO:0005524|GO:0008152|GO:0016301 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.1.168|MetaCyc: PWY-6478 BWK49_RS07205 0d862969d35b7f4ff8638b1083b69eaf 338 PRINTS PR00960 LmbP protein signature 105 126 6.4E-40 T 06-07-2017 IPR001174 Galactokinase/homoserine kinase GO:0005524|GO:0008152|GO:0016301 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.1.168|MetaCyc: PWY-6478 BWK49_RS07205 0d862969d35b7f4ff8638b1083b69eaf 338 PRINTS PR00960 LmbP protein signature 254 278 6.4E-40 T 06-07-2017 IPR001174 Galactokinase/homoserine kinase GO:0005524|GO:0008152|GO:0016301 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.1.168|MetaCyc: PWY-6478 BWK49_RS07205 0d862969d35b7f4ff8638b1083b69eaf 338 PRINTS PR00960 LmbP protein signature 147 166 6.4E-40 T 06-07-2017 IPR001174 Galactokinase/homoserine kinase GO:0005524|GO:0008152|GO:0016301 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.1.168|MetaCyc: PWY-6478 BWK49_RS07205 0d862969d35b7f4ff8638b1083b69eaf 338 SUPERFAMILY SSF54211 4 176 1.82E-36 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold BWK49_RS07205 0d862969d35b7f4ff8638b1083b69eaf 338 Pfam PF00288 GHMP kinases N terminal domain 99 167 1.3E-12 T 06-07-2017 IPR006204 GHMP kinase N-terminal domain GO:0005524 BWK49_RS07205 0d862969d35b7f4ff8638b1083b69eaf 338 PIRSF PIRSF036406 5 338 2.3E-109 T 06-07-2017 IPR014606 D,D-heptose 7-phosphate kinase KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.1.168|MetaCyc: PWY-6478 BWK49_RS02210 f6beaab8da26e026403395eeae5fad26 334 SUPERFAMILY SSF51989 40 332 2.62E-96 T 06-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 BWK49_RS02210 f6beaab8da26e026403395eeae5fad26 334 PIRSF PIRSF001100 1 334 1.4E-98 T 06-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 BWK49_RS02210 f6beaab8da26e026403395eeae5fad26 334 ProSitePatterns PS00656 Glycosyl hydrolases family 6 signature 2. 154 163 - T 06-07-2017 IPR001524 Glycoside hydrolase, family 6, conserved site GO:0004553|GO:0005975 BWK49_RS02210 f6beaab8da26e026403395eeae5fad26 334 Gene3D G3DSA:3.20.20.40 39 331 7.4E-91 T 06-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 BWK49_RS02210 f6beaab8da26e026403395eeae5fad26 334 Pfam PF01341 Glycosyl hydrolases family 6 66 317 7.5E-70 T 06-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 BWK49_RS02210 f6beaab8da26e026403395eeae5fad26 334 PRINTS PR00733 Glycosyl hydrolase family 6 signature 137 152 3.8E-39 T 06-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 BWK49_RS02210 f6beaab8da26e026403395eeae5fad26 334 PRINTS PR00733 Glycosyl hydrolase family 6 signature 222 232 3.8E-39 T 06-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 BWK49_RS02210 f6beaab8da26e026403395eeae5fad26 334 PRINTS PR00733 Glycosyl hydrolase family 6 signature 252 265 3.8E-39 T 06-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 BWK49_RS02210 f6beaab8da26e026403395eeae5fad26 334 PRINTS PR00733 Glycosyl hydrolase family 6 signature 69 88 3.8E-39 T 06-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 BWK49_RS02210 f6beaab8da26e026403395eeae5fad26 334 PRINTS PR00733 Glycosyl hydrolase family 6 signature 270 290 3.8E-39 T 06-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 BWK49_RS02210 f6beaab8da26e026403395eeae5fad26 334 PRINTS PR00733 Glycosyl hydrolase family 6 signature 294 308 3.8E-39 T 06-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 BWK49_RS02210 f6beaab8da26e026403395eeae5fad26 334 PRINTS PR00733 Glycosyl hydrolase family 6 signature 109 122 3.8E-39 T 06-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 BWK49_RS02210 f6beaab8da26e026403395eeae5fad26 334 PRINTS PR00733 Glycosyl hydrolase family 6 signature 192 205 3.8E-39 T 06-07-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 BWK49_RS07215 21f0eaad9123f80b0fdcfa08562a8b28 184 PIRSF PIRSF004682 3 181 1.1E-49 T 06-07-2017 IPR004446 D,D-heptose 1,7-bisphosphate phosphatase GO:0005975|GO:0016791 BWK49_RS07215 21f0eaad9123f80b0fdcfa08562a8b28 184 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 10 155 1.2E-29 T 06-07-2017 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 BWK49_RS07215 21f0eaad9123f80b0fdcfa08562a8b28 184 TIGRFAM TIGR01656 Histidinol-ppas: histidinol-phosphate phosphatase domain 11 151 2.0E-34 T 06-07-2017 IPR006543 Histidinol-phosphate phosphatase GO:0016791 BWK49_RS07215 21f0eaad9123f80b0fdcfa08562a8b28 184 Pfam PF13242 HAD-hyrolase-like 108 172 2.8E-12 T 06-07-2017 BWK49_RS07215 21f0eaad9123f80b0fdcfa08562a8b28 184 Gene3D G3DSA:3.40.50.1000 5 177 3.1E-51 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS07215 21f0eaad9123f80b0fdcfa08562a8b28 184 SUPERFAMILY SSF56784 6 178 7.59E-41 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS25000 2f5e15743c7aab7ea700d4ed3d3de7d8 261 Pfam PF12697 Alpha/beta hydrolase family 15 252 3.3E-21 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS25000 2f5e15743c7aab7ea700d4ed3d3de7d8 261 PRINTS PR00111 Alpha/beta hydrolase fold signature 97 110 1.4E-6 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS25000 2f5e15743c7aab7ea700d4ed3d3de7d8 261 PRINTS PR00111 Alpha/beta hydrolase fold signature 83 96 1.4E-6 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS25000 2f5e15743c7aab7ea700d4ed3d3de7d8 261 PRINTS PR00111 Alpha/beta hydrolase fold signature 203 217 1.4E-6 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS25000 2f5e15743c7aab7ea700d4ed3d3de7d8 261 PRINTS PR00111 Alpha/beta hydrolase fold signature 40 55 1.4E-6 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS25000 2f5e15743c7aab7ea700d4ed3d3de7d8 261 PRINTS PR00412 Epoxide hydrolase signature 97 110 9.9E-6 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS25000 2f5e15743c7aab7ea700d4ed3d3de7d8 261 PRINTS PR00412 Epoxide hydrolase signature 234 256 9.9E-6 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS25000 2f5e15743c7aab7ea700d4ed3d3de7d8 261 PRINTS PR00412 Epoxide hydrolase signature 40 55 9.9E-6 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS25000 2f5e15743c7aab7ea700d4ed3d3de7d8 261 SUPERFAMILY SSF53474 3 258 6.51E-55 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS25000 2f5e15743c7aab7ea700d4ed3d3de7d8 261 Gene3D G3DSA:3.40.50.1820 2 259 1.3E-55 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS26590 cff4a82d639e87cea54c4e742eb5ead3 317 SUPERFAMILY SSF53474 72 294 5.15E-28 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS26590 cff4a82d639e87cea54c4e742eb5ead3 317 Gene3D G3DSA:3.40.50.1820 71 188 1.9E-22 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS26590 cff4a82d639e87cea54c4e742eb5ead3 317 Gene3D G3DSA:3.40.50.1820 225 293 1.9E-22 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS12885 f2c0b8a90315dd0440f92a13a49f367f 214 Pfam PF10812 Protein of unknown function (DUF2561) 1 208 2.2E-92 T 06-07-2017 IPR024381 Protein of unknown function DUF2561 BWK49_RS12885 f2c0b8a90315dd0440f92a13a49f367f 214 ProDom PD111926 TRANSMEMBRANE MEMBRANE RV2197C/MT2253 PROBABLE ML0878 1 214 2.0E-72 T 06-07-2017 IPR024381 Protein of unknown function DUF2561 BWK49_RS12425 8b1382bbf166178b3d89abc0aa9cd1af 188 Gene3D G3DSA:1.10.357.10 12 183 4.7E-27 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS12425 8b1382bbf166178b3d89abc0aa9cd1af 188 ProSitePatterns PS01081 TetR-type HTH domain signature. 26 57 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site BWK49_RS12425 8b1382bbf166178b3d89abc0aa9cd1af 188 SUPERFAMILY SSF46689 10 70 1.6E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS12425 8b1382bbf166178b3d89abc0aa9cd1af 188 SUPERFAMILY SSF48498 79 180 3.56E-7 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS12425 8b1382bbf166178b3d89abc0aa9cd1af 188 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 60 4.9E-12 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS16045 3049c2bb0d916f2517f16861e6152b40 212 Pfam PF17197 Domain of unknown function (DUF5134) 36 207 2.9E-30 T 06-07-2017 IPR033458 Protein of unknown function DUF5134 BWK49_RS16045 3049c2bb0d916f2517f16861e6152b40 212 ProDom PD338207 MEMBRANE INTEGRAL TRANSMEMBRANE PLASMID PROBABLE MB0995 RV0970/MT0998 1 212 3.0E-45 T 06-07-2017 BWK49_RS03820 d4a7ee1eb42c59acea3e9fb9d1357ee2 285 Gene3D G3DSA:1.10.1040.10 164 281 1.1E-20 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 BWK49_RS03820 d4a7ee1eb42c59acea3e9fb9d1357ee2 285 SUPERFAMILY SSF48179 162 279 3.17E-17 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 BWK49_RS03820 d4a7ee1eb42c59acea3e9fb9d1357ee2 285 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 6 161 3.6E-43 T 06-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 BWK49_RS03820 d4a7ee1eb42c59acea3e9fb9d1357ee2 285 Gene3D G3DSA:3.40.50.720 6 162 2.0E-42 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS03820 d4a7ee1eb42c59acea3e9fb9d1357ee2 285 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 164 274 4.1E-13 T 06-07-2017 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 BWK49_RS03820 d4a7ee1eb42c59acea3e9fb9d1357ee2 285 PIRSF PIRSF000103 1 285 5.3E-67 T 06-07-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 BWK49_RS03820 d4a7ee1eb42c59acea3e9fb9d1357ee2 285 SUPERFAMILY SSF51735 5 162 3.01E-39 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS12835 72a831275c5d0e703ff18141215bd2af 178 SUPERFAMILY SSF52540 3 174 1.86E-33 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS12835 72a831275c5d0e703ff18141215bd2af 178 Pfam PF02283 Cobinamide kinase / cobinamide phosphate guanyltransferase 3 172 1.0E-51 T 06-07-2017 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00030+2.7.1.15|KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 BWK49_RS12835 72a831275c5d0e703ff18141215bd2af 178 PIRSF PIRSF006135 1 176 1.6E-52 T 06-07-2017 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00030+2.7.1.15|KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 BWK49_RS12835 72a831275c5d0e703ff18141215bd2af 178 Gene3D G3DSA:3.40.50.300 3 174 1.7E-49 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS14365 897092d6e49b92c1510c0946a38134b8 358 Gene3D G3DSA:1.50.10.20 25 187 6.7E-11 T 06-07-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid BWK49_RS14365 897092d6e49b92c1510c0946a38134b8 358 SUPERFAMILY SSF48208 22 334 2.38E-41 T 06-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 BWK49_RS15165 ff0ff5d4e4d86e810883eb6d144d27b5 238 Pfam PF02308 MgtC family 13 133 1.9E-32 T 06-07-2017 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 BWK49_RS15165 ff0ff5d4e4d86e810883eb6d144d27b5 238 PRINTS PR01837 MgtC/SapB protein signature 35 53 5.6E-40 T 06-07-2017 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 BWK49_RS15165 ff0ff5d4e4d86e810883eb6d144d27b5 238 PRINTS PR01837 MgtC/SapB protein signature 60 82 5.6E-40 T 06-07-2017 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 BWK49_RS15165 ff0ff5d4e4d86e810883eb6d144d27b5 238 PRINTS PR01837 MgtC/SapB protein signature 16 35 5.6E-40 T 06-07-2017 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 BWK49_RS15165 ff0ff5d4e4d86e810883eb6d144d27b5 238 PRINTS PR01837 MgtC/SapB protein signature 87 111 5.6E-40 T 06-07-2017 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 BWK49_RS26165 263e256902ca93843ddae7a2c7b564f2 558 Gene3D G3DSA:3.30.420.40 158 319 3.5E-16 T 06-07-2017 BWK49_RS26165 263e256902ca93843ddae7a2c7b564f2 558 SUPERFAMILY SSF53067 155 335 2.05E-29 T 06-07-2017 BWK49_RS26165 263e256902ca93843ddae7a2c7b564f2 558 Pfam PF00012 Hsp70 protein 101 335 6.5E-24 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 BWK49_RS14185 9f3da561786b62011ee2440223602a56 188 SUPERFAMILY SSF54534 83 185 9.04E-24 T 06-07-2017 BWK49_RS14185 9f3da561786b62011ee2440223602a56 188 Gene3D G3DSA:3.10.50.40 82 185 1.9E-22 T 06-07-2017 BWK49_RS14185 9f3da561786b62011ee2440223602a56 188 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 98 184 3.2E-13 T 06-07-2017 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 BWK49_RS01355 e4b14b9cc41822ee3802795d4874b795 66 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 12 59 2.3E-8 T 06-07-2017 IPR010093 SinI-like, DNA-binding domain GO:0003677 BWK49_RS01355 e4b14b9cc41822ee3802795d4874b795 66 SUPERFAMILY SSF46955 12 61 1.57E-5 T 06-07-2017 IPR009061 Putative DNA-binding domain BWK49_RS01355 e4b14b9cc41822ee3802795d4874b795 66 Pfam PF12728 Helix-turn-helix domain 12 61 1.8E-10 T 06-07-2017 BWK49_RS01965 1f7c90ae239c22eeede4fdbb9cef69a8 78 Gene3D G3DSA:3.40.50.720 2 38 1.6E-8 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS01965 1f7c90ae239c22eeede4fdbb9cef69a8 78 SUPERFAMILY SSF51735 1 42 5.19E-8 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS23175 88681a5c7d40851e42d7858c18e42b4d 379 Pfam PF13556 PucR C-terminal helix-turn-helix domain 307 361 1.2E-11 T 06-07-2017 IPR025736 PucR C-terminal helix-turn-helix domain BWK49_RS00315 83060d326a4b0a28920434ba734fcd8a 306 PRINTS PR00111 Alpha/beta hydrolase fold signature 126 139 2.9E-5 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS00315 83060d326a4b0a28920434ba734fcd8a 306 PRINTS PR00111 Alpha/beta hydrolase fold signature 81 96 2.9E-5 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS00315 83060d326a4b0a28920434ba734fcd8a 306 PRINTS PR00111 Alpha/beta hydrolase fold signature 140 153 2.9E-5 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS00315 83060d326a4b0a28920434ba734fcd8a 306 Gene3D G3DSA:3.40.50.1820 45 304 1.5E-36 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS00315 83060d326a4b0a28920434ba734fcd8a 306 Pfam PF12697 Alpha/beta hydrolase family 60 297 1.5E-18 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS00315 83060d326a4b0a28920434ba734fcd8a 306 SUPERFAMILY SSF53474 43 303 3.21E-37 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS08080 585c189b65b89a148cd9c32508baa2a9 285 Gene3D G3DSA:3.40.50.300 39 196 7.0E-26 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS08080 585c189b65b89a148cd9c32508baa2a9 285 Pfam PF08406 CbbQ/NirQ/NorQ C-terminal 193 275 1.5E-26 T 06-07-2017 IPR013615 CbbQ/NirQ/NorQ, C-terminal BWK49_RS08080 585c189b65b89a148cd9c32508baa2a9 285 SUPERFAMILY SSF52540 40 229 5.94E-30 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS08080 585c189b65b89a148cd9c32508baa2a9 285 Pfam PF07728 AAA domain (dynein-related subfamily) 47 180 3.0E-31 T 06-07-2017 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 BWK49_RS04140 bb8464d8115a6280410b8cdbe16823e5 304 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 26 298 4.9E-79 T 06-07-2017 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 BWK49_RS04140 bb8464d8115a6280410b8cdbe16823e5 304 SUPERFAMILY SSF161098 34 292 1.07E-36 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS04140 bb8464d8115a6280410b8cdbe16823e5 304 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 99 302 2.4E-25 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS04140 bb8464d8115a6280410b8cdbe16823e5 304 Gene3D G3DSA:1.10.3720.10 26 299 2.4E-39 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS12185 dc34c0b57cabc63915f95461f1c8baf4 534 TIGRFAM TIGR00831 a_cpa1: Na+/H+ antiporter 6 524 2.5E-184 T 06-07-2017 IPR004705 Cation/H+ exchanger, CPA1 family, bacteria GO:0006812|GO:0015299|GO:0016021 BWK49_RS12185 dc34c0b57cabc63915f95461f1c8baf4 534 Pfam PF00999 Sodium/hydrogen exchanger family 8 405 1.9E-65 T 06-07-2017 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 BWK49_RS27675 52de028addfc4e0a9aa995f4d93aafaf 279 SMART SM00382 33 218 3.1E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS27675 52de028addfc4e0a9aa995f4d93aafaf 279 SUPERFAMILY SSF52540 7 230 1.57E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS27675 52de028addfc4e0a9aa995f4d93aafaf 279 Gene3D G3DSA:3.40.50.300 7 230 4.2E-71 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS27675 52de028addfc4e0a9aa995f4d93aafaf 279 Pfam PF00005 ABC transporter 25 167 5.6E-31 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 BWK49_RS14550 6ae6440dcb7e925ac9526b94202eb3ab 387 Gene3D G3DSA:3.20.20.30 2 347 1.1E-73 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS14550 6ae6440dcb7e925ac9526b94202eb3ab 387 Pfam PF00296 Luciferase-like monooxygenase 5 311 4.1E-42 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS14550 6ae6440dcb7e925ac9526b94202eb3ab 387 SUPERFAMILY SSF51679 4 345 2.59E-68 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS16615 a2277e3eb6d3e166a73388fdf5c2f47b 272 Pfam PF02616 Segregation and condensation protein ScpA 32 256 1.9E-79 T 06-07-2017 IPR003768 Segregation and condensation protein A BWK49_RS25565 5a7dae0d5f6a3b47879adc5701ca16cb 182 Pfam PF05423 Mycobacterium membrane protein 36 182 1.1E-33 T 06-07-2017 IPR008693 Transport accessory protein MmpS BWK49_RS06130 8d0ec6e60ca008431fdd603fc482b487 94 Pfam PF07045 Domain of unknown function (DUF1330) 3 93 7.0E-29 T 06-07-2017 IPR010753 Domain of unknown function DUF1330 BWK49_RS06130 8d0ec6e60ca008431fdd603fc482b487 94 Gene3D G3DSA:3.30.70.900 2 93 5.2E-28 T 06-07-2017 BWK49_RS06130 8d0ec6e60ca008431fdd603fc482b487 94 SUPERFAMILY SSF54909 2 93 1.84E-23 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel BWK49_RS25305 d465a639ff5751ccad84d7f3d4a304ba 308 Pfam PF02353 Mycolic acid cyclopropane synthetase 11 304 1.6E-103 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS25305 d465a639ff5751ccad84d7f3d4a304ba 308 Gene3D G3DSA:3.40.50.150 15 307 6.9E-75 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS25305 d465a639ff5751ccad84d7f3d4a304ba 308 SUPERFAMILY SSF53335 19 308 1.3E-66 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS25305 d465a639ff5751ccad84d7f3d4a304ba 308 PIRSF PIRSF003085 6 308 1.6E-89 T 06-07-2017 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 BWK49_RS22855 6b2937229b1878e8f3cb646b9e8c0136 202 Gene3D G3DSA:1.10.357.10 15 201 5.5E-29 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS22855 6b2937229b1878e8f3cb646b9e8c0136 202 SUPERFAMILY SSF46689 17 90 2.84E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS22855 6b2937229b1878e8f3cb646b9e8c0136 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 50 73 1.3E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS22855 6b2937229b1878e8f3cb646b9e8c0136 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 42 1.3E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS22855 6b2937229b1878e8f3cb646b9e8c0136 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 29 75 9.5E-15 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS22855 6b2937229b1878e8f3cb646b9e8c0136 202 SUPERFAMILY SSF48498 88 199 5.72E-7 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS15215 c590a16cee3d0319a29376c96881cf00 609 PRINTS PR00819 CbxX/CfqX superfamily signature 475 494 1.3E-33 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 BWK49_RS15215 c590a16cee3d0319a29376c96881cf00 609 PRINTS PR00819 CbxX/CfqX superfamily signature 352 367 1.3E-33 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 BWK49_RS15215 c590a16cee3d0319a29376c96881cf00 609 PRINTS PR00819 CbxX/CfqX superfamily signature 390 404 1.3E-33 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 BWK49_RS15215 c590a16cee3d0319a29376c96881cf00 609 PRINTS PR00819 CbxX/CfqX superfamily signature 458 475 1.3E-33 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 BWK49_RS15215 c590a16cee3d0319a29376c96881cf00 609 PRINTS PR00819 CbxX/CfqX superfamily signature 404 423 1.3E-33 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 BWK49_RS15215 c590a16cee3d0319a29376c96881cf00 609 PRINTS PR00819 CbxX/CfqX superfamily signature 545 557 1.3E-33 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 BWK49_RS15215 c590a16cee3d0319a29376c96881cf00 609 PRINTS PR00819 CbxX/CfqX superfamily signature 437 449 1.3E-33 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 BWK49_RS15215 c590a16cee3d0319a29376c96881cf00 609 PRINTS PR00819 CbxX/CfqX superfamily signature 312 326 1.3E-33 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 BWK49_RS15215 c590a16cee3d0319a29376c96881cf00 609 SMART SM00382 349 490 5.8E-5 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS15215 c590a16cee3d0319a29376c96881cf00 609 SUPERFAMILY SSF48452 34 58 1.28E-8 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 BWK49_RS15215 c590a16cee3d0319a29376c96881cf00 609 SUPERFAMILY SSF48452 118 256 1.28E-8 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 BWK49_RS15215 c590a16cee3d0319a29376c96881cf00 609 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 354 486 5.0E-17 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 BWK49_RS15215 c590a16cee3d0319a29376c96881cf00 609 TIGRFAM TIGR03922 T7SS_EccA: type VII secretion AAA-ATPase EccA 42 593 1.7E-248 T 06-07-2017 IPR023835 Type VII secretion system AAA-ATPase, EccA BWK49_RS15215 c590a16cee3d0319a29376c96881cf00 609 Gene3D G3DSA:1.25.40.10 34 65 8.7E-9 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 BWK49_RS15215 c590a16cee3d0319a29376c96881cf00 609 Gene3D G3DSA:1.25.40.10 114 261 8.7E-9 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 BWK49_RS15215 c590a16cee3d0319a29376c96881cf00 609 SUPERFAMILY SSF52540 314 577 2.99E-27 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS15215 c590a16cee3d0319a29376c96881cf00 609 Gene3D G3DSA:3.40.50.300 312 500 2.7E-23 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS05820 c2ad6df965b6801d581fa706e02ce50c 112 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 28 101 1.7E-15 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 BWK49_RS05820 c2ad6df965b6801d581fa706e02ce50c 112 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 60 68 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 BWK49_RS05820 c2ad6df965b6801d581fa706e02ce50c 112 Gene3D G3DSA:3.10.20.30 14 109 8.2E-28 T 06-07-2017 IPR012675 Beta-grasp domain BWK49_RS05820 c2ad6df965b6801d581fa706e02ce50c 112 SUPERFAMILY SSF54292 12 110 1.84E-26 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 BWK49_RS19805 3d6d0ae1ca04df980512717fb5c82159 341 Gene3D G3DSA:3.20.20.70 7 324 2.1E-53 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 BWK49_RS19805 3d6d0ae1ca04df980512717fb5c82159 341 Pfam PF03060 Nitronate monooxygenase 8 338 1.3E-101 T 06-07-2017 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 BWK49_RS19805 3d6d0ae1ca04df980512717fb5c82159 341 SUPERFAMILY SSF51412 3 72 7.94E-50 T 06-07-2017 BWK49_RS19805 3d6d0ae1ca04df980512717fb5c82159 341 SUPERFAMILY SSF51412 107 290 7.94E-50 T 06-07-2017 BWK49_RS21055 99ccaa1f461f30c06d4a234ef32e52af 198 Pfam PF14032 PknH-like extracellular domain 30 183 2.6E-14 T 06-07-2017 IPR026954 PknH-like extracellular domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 BWK49_RS15295 6fefd64bba0787fe7424fda5114b8f97 387 Pfam PF00067 Cytochrome P450 196 383 4.3E-18 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS15295 6fefd64bba0787fe7424fda5114b8f97 387 SUPERFAMILY SSF48264 27 386 6.16E-76 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS15295 6fefd64bba0787fe7424fda5114b8f97 387 PRINTS PR00385 P450 superfamily signature 327 336 3.0E-8 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS15295 6fefd64bba0787fe7424fda5114b8f97 387 PRINTS PR00385 P450 superfamily signature 226 243 3.0E-8 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS15295 6fefd64bba0787fe7424fda5114b8f97 387 PRINTS PR00385 P450 superfamily signature 336 347 3.0E-8 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS15295 6fefd64bba0787fe7424fda5114b8f97 387 PRINTS PR00385 P450 superfamily signature 261 272 3.0E-8 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS15295 6fefd64bba0787fe7424fda5114b8f97 387 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 329 338 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 BWK49_RS15295 6fefd64bba0787fe7424fda5114b8f97 387 Gene3D G3DSA:1.10.630.10 29 386 5.5E-90 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS15295 6fefd64bba0787fe7424fda5114b8f97 387 PRINTS PR00359 B-class P450 signature 261 272 3.2E-33 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS15295 6fefd64bba0787fe7424fda5114b8f97 387 PRINTS PR00359 B-class P450 signature 145 160 3.2E-33 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS15295 6fefd64bba0787fe7424fda5114b8f97 387 PRINTS PR00359 B-class P450 signature 82 93 3.2E-33 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS15295 6fefd64bba0787fe7424fda5114b8f97 387 PRINTS PR00359 B-class P450 signature 183 205 3.2E-33 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS15295 6fefd64bba0787fe7424fda5114b8f97 387 PRINTS PR00359 B-class P450 signature 327 336 3.2E-33 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS15295 6fefd64bba0787fe7424fda5114b8f97 387 PRINTS PR00359 B-class P450 signature 278 305 3.2E-33 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS15295 6fefd64bba0787fe7424fda5114b8f97 387 PRINTS PR00359 B-class P450 signature 128 144 3.2E-33 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS15295 6fefd64bba0787fe7424fda5114b8f97 387 PRINTS PR00359 B-class P450 signature 336 347 3.2E-33 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS29010 e3fd63525015baf080f59d5294e864cf 514 Gene3D G3DSA:3.40.50.200 193 451 1.1E-66 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 BWK49_RS29010 e3fd63525015baf080f59d5294e864cf 514 Gene3D G3DSA:3.40.50.200 15 95 1.1E-66 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 BWK49_RS29010 e3fd63525015baf080f59d5294e864cf 514 Pfam PF00082 Subtilase family 191 443 1.7E-21 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 BWK49_RS29010 e3fd63525015baf080f59d5294e864cf 514 PRINTS PR00723 Subtilisin serine protease family (S8) signature 75 88 1.9E-9 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related BWK49_RS29010 e3fd63525015baf080f59d5294e864cf 514 PRINTS PR00723 Subtilisin serine protease family (S8) signature 39 58 1.9E-9 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related BWK49_RS29010 e3fd63525015baf080f59d5294e864cf 514 PRINTS PR00723 Subtilisin serine protease family (S8) signature 393 409 1.9E-9 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related BWK49_RS29010 e3fd63525015baf080f59d5294e864cf 514 SUPERFAMILY SSF52743 191 452 1.48E-44 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 BWK49_RS29010 e3fd63525015baf080f59d5294e864cf 514 SUPERFAMILY SSF52743 22 93 1.48E-44 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 BWK49_RS29010 e3fd63525015baf080f59d5294e864cf 514 TIGRFAM TIGR03921 T7SS_mycosin: type VII secretion-associated serine protease mycosin 191 511 2.1E-86 T 06-07-2017 IPR023834 Type VII secretion system peptidase S8A, mycosin-1 BWK49_RS29010 e3fd63525015baf080f59d5294e864cf 514 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 44 54 - T 06-07-2017 IPR023827 Peptidase S8, subtilisin, Asp-active site BWK49_RS23810 d4b423202010e6522b44a0dea72f6a1e 242 SUPERFAMILY SSF49329 46 180 1.18E-30 T 06-07-2017 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 BWK49_RS23810 d4b423202010e6522b44a0dea72f6a1e 242 Pfam PF00080 Copper/zinc superoxide dismutase (SODC) 57 180 5.2E-23 T 06-07-2017 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 BWK49_RS23810 d4b423202010e6522b44a0dea72f6a1e 242 Gene3D G3DSA:2.60.40.200 46 181 2.8E-30 T 06-07-2017 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 BWK49_RS01865 2c2a1ee935632107e407ec9cc1c28216 454 ProSitePatterns PS00570 Bacterial ring hydroxylating dioxygenases alpha-subunit signature. 97 120 - T 06-07-2017 IPR015881 Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site GO:0005506|GO:0016705|GO:0051537|GO:0055114 BWK49_RS01865 2c2a1ee935632107e407ec9cc1c28216 454 SUPERFAMILY SSF50022 22 169 5.76E-44 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS01865 2c2a1ee935632107e407ec9cc1c28216 454 Pfam PF00355 Rieske [2Fe-2S] domain 55 137 2.1E-20 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS01865 2c2a1ee935632107e407ec9cc1c28216 454 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 195 217 3.2E-46 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS01865 2c2a1ee935632107e407ec9cc1c28216 454 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 154 180 3.2E-46 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS01865 2c2a1ee935632107e407ec9cc1c28216 454 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 69 84 3.2E-46 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS01865 2c2a1ee935632107e407ec9cc1c28216 454 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 90 110 3.2E-46 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS01865 2c2a1ee935632107e407ec9cc1c28216 454 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 111 131 3.2E-46 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS01865 2c2a1ee935632107e407ec9cc1c28216 454 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 39 64 3.2E-46 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS01865 2c2a1ee935632107e407ec9cc1c28216 454 Gene3D G3DSA:2.102.10.10 46 136 2.4E-19 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS01865 2c2a1ee935632107e407ec9cc1c28216 454 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 177 445 1.5E-21 T 06-07-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 BWK49_RS01865 2c2a1ee935632107e407ec9cc1c28216 454 SUPERFAMILY SSF55961 171 447 4.95E-61 T 06-07-2017 BWK49_RS01865 2c2a1ee935632107e407ec9cc1c28216 454 Gene3D G3DSA:3.90.380.10 142 448 7.3E-102 T 06-07-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 BWK49_RS07330 318e7447575ebf1a773317a9de4f3adc 161 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 2 136 8.6E-12 T 06-07-2017 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 BWK49_RS07330 318e7447575ebf1a773317a9de4f3adc 161 Gene3D G3DSA:3.40.50.2000 2 134 1.5E-13 T 06-07-2017 BWK49_RS07330 318e7447575ebf1a773317a9de4f3adc 161 SUPERFAMILY SSF53756 16 134 1.7E-6 T 06-07-2017 BWK49_RS25615 b9b7f981e4ff8a8e41dd658109bd6eca 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 1.9E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS25615 b9b7f981e4ff8a8e41dd658109bd6eca 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 1.9E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS25615 b9b7f981e4ff8a8e41dd658109bd6eca 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 1.9E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS25615 b9b7f981e4ff8a8e41dd658109bd6eca 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 1.9E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS25615 b9b7f981e4ff8a8e41dd658109bd6eca 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 1.9E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS25615 b9b7f981e4ff8a8e41dd658109bd6eca 274 PIRSF PIRSF000126 4 273 4.5E-68 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS25615 b9b7f981e4ff8a8e41dd658109bd6eca 274 Pfam PF00106 short chain dehydrogenase 11 199 9.4E-47 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS25615 b9b7f981e4ff8a8e41dd658109bd6eca 274 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 10 193 7.0E-4 T 06-07-2017 BWK49_RS25615 b9b7f981e4ff8a8e41dd658109bd6eca 274 SUPERFAMILY SSF51735 10 262 1.18E-64 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS25615 b9b7f981e4ff8a8e41dd658109bd6eca 274 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 2.0E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS25615 b9b7f981e4ff8a8e41dd658109bd6eca 274 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 2.0E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS25615 b9b7f981e4ff8a8e41dd658109bd6eca 274 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 2.0E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS25615 b9b7f981e4ff8a8e41dd658109bd6eca 274 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS25615 b9b7f981e4ff8a8e41dd658109bd6eca 274 Gene3D G3DSA:3.40.50.720 11 259 4.9E-65 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS00190 ca7736531b82647a8a06855a06116b49 460 SUPERFAMILY SSF56645 2 231 2.36E-55 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS00190 ca7736531b82647a8a06855a06116b49 460 SUPERFAMILY SSF47203 256 399 6.28E-49 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS00190 ca7736531b82647a8a06855a06116b49 460 Gene3D G3DSA:2.40.110.10 124 219 7.2E-37 T 06-07-2017 BWK49_RS00190 ca7736531b82647a8a06855a06116b49 460 Gene3D G3DSA:1.10.540.10 3 114 8.7E-19 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS00190 ca7736531b82647a8a06855a06116b49 460 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 255 398 1.8E-45 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS00190 ca7736531b82647a8a06855a06116b49 460 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 357 376 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 BWK49_RS00190 ca7736531b82647a8a06855a06116b49 460 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 125 220 1.2E-23 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 BWK49_RS00190 ca7736531b82647a8a06855a06116b49 460 Gene3D G3DSA:1.20.140.10 220 398 4.6E-59 T 06-07-2017 BWK49_RS00190 ca7736531b82647a8a06855a06116b49 460 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 113 1.0E-9 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS20285 4a1d1cd01700eba6becdb631b3000dce 328 SUPERFAMILY SSF56601 82 312 1.59E-16 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like BWK49_RS20285 4a1d1cd01700eba6becdb631b3000dce 328 Gene3D G3DSA:3.40.710.10 90 316 1.9E-9 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like BWK49_RS22265 1160e15fe7d9bbb43cbdc24ddfe99c02 597 Pfam PF08447 PAS fold 337 417 4.4E-11 T 06-07-2017 IPR013655 PAS fold-3 GO:0005515 BWK49_RS22265 1160e15fe7d9bbb43cbdc24ddfe99c02 597 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 433 596 1.9E-40 T 06-07-2017 IPR000160 GGDEF domain BWK49_RS22265 1160e15fe7d9bbb43cbdc24ddfe99c02 597 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 311 433 4.8E-9 T 06-07-2017 IPR000014 PAS domain BWK49_RS22265 1160e15fe7d9bbb43cbdc24ddfe99c02 597 SMART SM00267 426 597 9.1E-57 T 06-07-2017 IPR000160 GGDEF domain BWK49_RS22265 1160e15fe7d9bbb43cbdc24ddfe99c02 597 Gene3D G3DSA:3.30.70.270 439 595 9.1E-50 T 06-07-2017 BWK49_RS22265 1160e15fe7d9bbb43cbdc24ddfe99c02 597 SUPERFAMILY SSF55785 305 420 9.18E-15 T 06-07-2017 IPR000014 PAS domain BWK49_RS22265 1160e15fe7d9bbb43cbdc24ddfe99c02 597 Gene3D G3DSA:3.30.450.20 305 421 1.1E-17 T 06-07-2017 BWK49_RS22265 1160e15fe7d9bbb43cbdc24ddfe99c02 597 Pfam PF00990 Diguanylate cyclase, GGDEF domain 437 592 3.4E-44 T 06-07-2017 IPR000160 GGDEF domain BWK49_RS22265 1160e15fe7d9bbb43cbdc24ddfe99c02 597 SUPERFAMILY SSF55073 442 595 3.53E-43 T 06-07-2017 IPR029787 Nucleotide cyclase BWK49_RS23685 3ac22f9ba8ad95d7ff691fefd30a878b 399 Gene3D G3DSA:1.10.630.10 8 397 1.6E-103 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS23685 3ac22f9ba8ad95d7ff691fefd30a878b 399 Pfam PF00067 Cytochrome P450 189 368 4.4E-18 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS23685 3ac22f9ba8ad95d7ff691fefd30a878b 399 SUPERFAMILY SSF48264 13 397 3.67E-81 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS23685 3ac22f9ba8ad95d7ff691fefd30a878b 399 PRINTS PR00359 B-class P450 signature 83 94 1.5E-44 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS23685 3ac22f9ba8ad95d7ff691fefd30a878b 399 PRINTS PR00359 B-class P450 signature 145 160 1.5E-44 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS23685 3ac22f9ba8ad95d7ff691fefd30a878b 399 PRINTS PR00359 B-class P450 signature 186 208 1.5E-44 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS23685 3ac22f9ba8ad95d7ff691fefd30a878b 399 PRINTS PR00359 B-class P450 signature 271 282 1.5E-44 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS23685 3ac22f9ba8ad95d7ff691fefd30a878b 399 PRINTS PR00359 B-class P450 signature 316 331 1.5E-44 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS23685 3ac22f9ba8ad95d7ff691fefd30a878b 399 PRINTS PR00359 B-class P450 signature 288 315 1.5E-44 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS23685 3ac22f9ba8ad95d7ff691fefd30a878b 399 PRINTS PR00359 B-class P450 signature 339 348 1.5E-44 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS23685 3ac22f9ba8ad95d7ff691fefd30a878b 399 PRINTS PR00359 B-class P450 signature 348 359 1.5E-44 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS23685 3ac22f9ba8ad95d7ff691fefd30a878b 399 PRINTS PR00359 B-class P450 signature 128 144 1.5E-44 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS06740 865379cfd7444865ef3d717de3da72af 243 Gene3D G3DSA:3.90.226.10 4 241 1.8E-58 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS06740 865379cfd7444865ef3d717de3da72af 243 SUPERFAMILY SSF52096 4 242 1.03E-58 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS06740 865379cfd7444865ef3d717de3da72af 243 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 90 110 - T 06-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 BWK49_RS06740 865379cfd7444865ef3d717de3da72af 243 Pfam PF00378 Enoyl-CoA hydratase/isomerase 7 242 1.0E-40 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 BWK49_RS03890 61924c835158656a2369726f22eabd42 296 Gene3D G3DSA:3.30.470.20 106 236 3.3E-53 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 BWK49_RS03890 61924c835158656a2369726f22eabd42 296 Pfam PF01259 SAICAR synthetase 9 256 6.8E-95 T 06-07-2017 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 BWK49_RS03890 61924c835158656a2369726f22eabd42 296 ProSitePatterns PS01057 SAICAR synthetase signature 1. 94 108 - T 06-07-2017 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 BWK49_RS03890 61924c835158656a2369726f22eabd42 296 Gene3D G3DSA:3.30.200.20 4 105 3.2E-37 T 06-07-2017 BWK49_RS03890 61924c835158656a2369726f22eabd42 296 ProSitePatterns PS01058 SAICAR synthetase signature 2. 193 201 - T 06-07-2017 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 BWK49_RS03890 61924c835158656a2369726f22eabd42 296 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 8 284 8.7E-71 T 06-07-2017 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 BWK49_RS03890 61924c835158656a2369726f22eabd42 296 SUPERFAMILY SSF56104 6 287 5.56E-95 T 06-07-2017 BWK49_RS03890 61924c835158656a2369726f22eabd42 296 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 7 285 24.316 T 06-07-2017 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 BWK49_RS00680 896131e18d86be91c1cc40901a69f80a 229 Pfam PF13847 Methyltransferase domain 49 148 9.0E-14 T 06-07-2017 IPR025714 Methyltransferase domain BWK49_RS00680 896131e18d86be91c1cc40901a69f80a 229 Gene3D G3DSA:3.40.50.150 27 194 1.8E-34 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS00680 896131e18d86be91c1cc40901a69f80a 229 SUPERFAMILY SSF53335 5 192 1.45E-35 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS09210 6c8fe275c2c8e340ecf3261ea4ae4b9a 400 Pfam PF02515 CoA-transferase family III 8 374 7.0E-57 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 BWK49_RS09210 6c8fe275c2c8e340ecf3261ea4ae4b9a 400 SUPERFAMILY SSF89796 6 398 9.55E-77 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS09210 6c8fe275c2c8e340ecf3261ea4ae4b9a 400 Gene3D G3DSA:3.40.50.10540 305 398 1.3E-64 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS09210 6c8fe275c2c8e340ecf3261ea4ae4b9a 400 Gene3D G3DSA:3.40.50.10540 4 211 1.3E-64 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS09210 6c8fe275c2c8e340ecf3261ea4ae4b9a 400 Gene3D G3DSA:3.30.1540.10 231 304 2.7E-6 T 06-07-2017 BWK49_RS05910 c83a744bb7d05258235100f01b190ddb 316 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 10 308 6.6E-51 T 06-07-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 BWK49_RS05910 c83a744bb7d05258235100f01b190ddb 316 Gene3D G3DSA:3.40.830.10 235 313 3.1E-77 T 06-07-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 BWK49_RS05910 c83a744bb7d05258235100f01b190ddb 316 Gene3D G3DSA:3.40.830.10 7 191 3.1E-77 T 06-07-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 BWK49_RS05910 c83a744bb7d05258235100f01b190ddb 316 SUPERFAMILY SSF53213 233 310 6.54E-69 T 06-07-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 BWK49_RS05910 c83a744bb7d05258235100f01b190ddb 316 SUPERFAMILY SSF53213 8 189 6.54E-69 T 06-07-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 BWK49_RS05910 c83a744bb7d05258235100f01b190ddb 316 Hamap MF_01653 2,3-dihydroxyphenylpropionate/2,3-dihydroxicinnamic acid 1,2-dioxygenase [mhpB]. 5 316 53.599 T 06-07-2017 IPR023789 2,3-dihydroxyphenylpropionate/2,3-dihydroxicinnamic acid 1,2-dioxygenase GO:0005506|GO:0019439|GO:0047070|GO:0055114 KEGG: 00360+1.13.11.16|MetaCyc: PWY-6690 BWK49_RS08510 c1c9e118caa7ec1b68bcc3b2fc1216e9 321 SUPERFAMILY SSF52540 12 224 1.2E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS08510 c1c9e118caa7ec1b68bcc3b2fc1216e9 321 Pfam PF00005 ABC transporter 27 165 9.1E-26 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 BWK49_RS08510 c1c9e118caa7ec1b68bcc3b2fc1216e9 321 Gene3D G3DSA:3.40.50.300 9 224 2.3E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS08510 c1c9e118caa7ec1b68bcc3b2fc1216e9 321 SMART SM00382 36 222 3.9E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS08510 c1c9e118caa7ec1b68bcc3b2fc1216e9 321 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 BWK49_RS22595 90b820abe62cb68b1d8f5f38a0d539e3 992 Hamap MF_01600 UPF0182 protein . 11 904 17.728 T 06-07-2017 IPR005372 Uncharacterised protein family UPF0182 GO:0016021 BWK49_RS22595 90b820abe62cb68b1d8f5f38a0d539e3 992 Pfam PF03699 Uncharacterised protein family (UPF0182) 21 820 2.6E-267 T 06-07-2017 IPR005372 Uncharacterised protein family UPF0182 GO:0016021 BWK49_RS23890 ed2b0fc8d565e40af77cdf9e8c6ad5fc 621 Gene3D G3DSA:3.60.20.10 2 238 6.0E-73 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal BWK49_RS23890 ed2b0fc8d565e40af77cdf9e8c6ad5fc 621 Gene3D G3DSA:3.40.50.10490 253 450 2.2E-69 T 06-07-2017 BWK49_RS23890 ed2b0fc8d565e40af77cdf9e8c6ad5fc 621 SUPERFAMILY SSF56235 2 236 1.8E-66 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal BWK49_RS23890 ed2b0fc8d565e40af77cdf9e8c6ad5fc 621 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 621 40.731 T 06-07-2017 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 BWK49_RS23890 ed2b0fc8d565e40af77cdf9e8c6ad5fc 621 Gene3D G3DSA:3.40.50.10490 451 621 1.6E-58 T 06-07-2017 BWK49_RS23890 ed2b0fc8d565e40af77cdf9e8c6ad5fc 621 SUPERFAMILY SSF53697 254 621 1.95E-105 T 06-07-2017 BWK49_RS23890 ed2b0fc8d565e40af77cdf9e8c6ad5fc 621 Pfam PF13522 Glutamine amidotransferase domain 67 200 1.4E-21 T 06-07-2017 BWK49_RS23890 ed2b0fc8d565e40af77cdf9e8c6ad5fc 621 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 621 3.1E-246 T 06-07-2017 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 BWK49_RS23890 ed2b0fc8d565e40af77cdf9e8c6ad5fc 621 Pfam PF01380 SIS domain 470 600 2.4E-21 T 06-07-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 BWK49_RS23890 ed2b0fc8d565e40af77cdf9e8c6ad5fc 621 Pfam PF01380 SIS domain 298 422 3.8E-34 T 06-07-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 BWK49_RS13530 2be4f1fdc95871f7c6eb5d35940a025b 243 SUPERFAMILY SSF161098 44 230 2.35E-31 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS13530 2be4f1fdc95871f7c6eb5d35940a025b 243 Gene3D G3DSA:1.10.3720.10 43 238 5.3E-23 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS13530 2be4f1fdc95871f7c6eb5d35940a025b 243 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 68 238 6.6E-25 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS19910 bcc8b2375509f690f4d13a867b0ca674 162 Pfam PF02033 Ribosome-binding factor A 6 113 7.1E-22 T 06-07-2017 IPR000238 Ribosome-binding factor A GO:0006364 BWK49_RS19910 bcc8b2375509f690f4d13a867b0ca674 162 ProSitePatterns PS01319 Ribosome-binding factor A signature. 79 100 - T 06-07-2017 IPR020053 Ribosome-binding factor A, conserved site GO:0006364 BWK49_RS19910 bcc8b2375509f690f4d13a867b0ca674 162 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 2 120 18.008 T 06-07-2017 IPR000238 Ribosome-binding factor A GO:0006364 BWK49_RS19910 bcc8b2375509f690f4d13a867b0ca674 162 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 9 89 2.0E-28 T 06-07-2017 IPR000238 Ribosome-binding factor A GO:0006364 BWK49_RS19910 bcc8b2375509f690f4d13a867b0ca674 162 Gene3D G3DSA:3.30.300.20 3 120 2.6E-30 T 06-07-2017 IPR015946 K homology domain-like, alpha/beta BWK49_RS19910 bcc8b2375509f690f4d13a867b0ca674 162 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 1 114 7.4E-17 T 06-07-2017 IPR000238 Ribosome-binding factor A GO:0006364 BWK49_RS19910 bcc8b2375509f690f4d13a867b0ca674 162 SUPERFAMILY SSF89919 1 116 8.24E-26 T 06-07-2017 IPR023799 Ribosome-binding factor A domain BWK49_RS08830 b233974df1d0edfb45851124947e9b88 292 Gene3D G3DSA:3.20.20.30 17 287 2.3E-50 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS08830 b233974df1d0edfb45851124947e9b88 292 SUPERFAMILY SSF51679 12 290 6.02E-51 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS08830 b233974df1d0edfb45851124947e9b88 292 Pfam PF00296 Luciferase-like monooxygenase 18 242 3.7E-35 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS17280 a1b17e859e6b62f88cd719334dc091de 226 Pfam PF09534 Tryptophan-associated transmembrane protein (Trp_oprn_chp) 21 215 8.2E-45 T 06-07-2017 IPR019051 Trp biosynthesis associated, transmembrane protein, Oprn/Chp BWK49_RS17280 a1b17e859e6b62f88cd719334dc091de 226 TIGRFAM TIGR02234 trp_oprn_chp: membrane protein, TIGR02234 family 15 216 8.7E-68 T 06-07-2017 IPR011746 Trp biosynthesis associated, conserved hypothetical membrane protein BWK49_RS15310 b6460bf240ce969d10632ac8cb482298 727 Pfam PF02446 4-alpha-glucanotransferase 179 681 3.7E-115 T 06-07-2017 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 BWK49_RS15310 b6460bf240ce969d10632ac8cb482298 727 TIGRFAM TIGR00217 malQ: 4-alpha-glucanotransferase 132 689 3.6E-95 T 06-07-2017 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 BWK49_RS15310 b6460bf240ce969d10632ac8cb482298 727 SUPERFAMILY SSF51445 626 703 3.01E-138 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily BWK49_RS15310 b6460bf240ce969d10632ac8cb482298 727 SUPERFAMILY SSF51445 172 597 3.01E-138 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily BWK49_RS15310 b6460bf240ce969d10632ac8cb482298 727 Gene3D G3DSA:3.20.20.80 171 684 1.7E-158 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 BWK49_RS23920 19c1f845e0108ab07a99c420b19e602c 459 SUPERFAMILY SSF140453 62 131 5.36E-5 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like BWK49_RS20715 1f1f21c637c4ce0ed4c23ac11ab9abd8 233 SUPERFAMILY SSF161111 41 227 9.68E-23 T 06-07-2017 BWK49_RS20715 1f1f21c637c4ce0ed4c23ac11ab9abd8 233 Pfam PF01545 Cation efflux family 48 222 5.9E-7 T 06-07-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 BWK49_RS20715 1f1f21c637c4ce0ed4c23ac11ab9abd8 233 Gene3D G3DSA:1.20.1510.10 44 224 1.6E-10 T 06-07-2017 IPR027469 Cation efflux protein transmembrane domain BWK49_RS20095 b601fa92c280a5e2238a55b2f4b55c4b 293 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 9 220 6.8E-16 T 06-07-2017 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 BWK49_RS05555 854b21398d7a2bd52faa208900152c98 360 SUPERFAMILY SSF51735 7 144 8.96E-12 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS05555 854b21398d7a2bd52faa208900152c98 360 Gene3D G3DSA:3.40.50.720 5 163 2.7E-18 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS23590 fedd0e0fa83909cf90df7c9301ba2372 930 SMART SM00387 518 636 7.2E-14 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS23590 fedd0e0fa83909cf90df7c9301ba2372 930 Pfam PF00672 HAMP domain 321 400 1.7E-12 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 BWK49_RS23590 fedd0e0fa83909cf90df7c9301ba2372 930 Gene3D G3DSA:3.30.565.10 484 634 1.2E-13 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS23590 fedd0e0fa83909cf90df7c9301ba2372 930 SMART SM00304 339 406 2.0E-4 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 BWK49_RS23590 fedd0e0fa83909cf90df7c9301ba2372 930 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 523 635 3.8E-9 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS23590 fedd0e0fa83909cf90df7c9301ba2372 930 SUPERFAMILY SSF55874 508 635 8.38E-17 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS05580 811b26bd28243e0a4e6f388a7266ae76 239 Pfam PF00872 Transposase, Mutator family 3 189 4.2E-36 T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 BWK49_RS03480 631611a361fd514f03907025a0b14336 381 Gene3D G3DSA:3.40.50.300 222 348 2.5E-9 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS03480 631611a361fd514f03907025a0b14336 381 Gene3D G3DSA:3.40.50.300 88 146 2.5E-9 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS03480 631611a361fd514f03907025a0b14336 381 SUPERFAMILY SSF52540 212 347 1.91E-31 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS03480 631611a361fd514f03907025a0b14336 381 SUPERFAMILY SSF52540 85 134 1.91E-31 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS03480 631611a361fd514f03907025a0b14336 381 Pfam PF13469 Sulfotransferase family 90 338 8.0E-60 T 06-07-2017 BWK49_RS22720 85a809ba7ca407b2053925a497224a48 196 SUPERFAMILY SSF53254 7 194 8.64E-44 T 06-07-2017 IPR029033 Histidine phosphatase superfamily BWK49_RS22720 85a809ba7ca407b2053925a497224a48 196 Gene3D G3DSA:3.40.50.1240 6 194 8.0E-43 T 06-07-2017 IPR029033 Histidine phosphatase superfamily BWK49_RS22720 85a809ba7ca407b2053925a497224a48 196 SMART SM00855 7 154 1.7E-17 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 BWK49_RS22720 85a809ba7ca407b2053925a497224a48 196 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 8 192 5.7E-43 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 BWK49_RS27880 271f4b4343cce785311155a3d175e709 247 SUPERFAMILY SSF53474 37 227 2.67E-42 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS27880 271f4b4343cce785311155a3d175e709 247 Gene3D G3DSA:3.40.50.1820 37 228 4.3E-55 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS27880 271f4b4343cce785311155a3d175e709 247 SMART SM01110 36 228 4.5E-92 T 06-07-2017 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 BWK49_RS27880 271f4b4343cce785311155a3d175e709 247 Pfam PF01083 Cutinase 37 226 8.8E-47 T 06-07-2017 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 BWK49_RS03650 2508781973890bc187fb484a5f7f0e2d 493 Gene3D G3DSA:3.40.50.2000 17 272 6.4E-84 T 06-07-2017 BWK49_RS03650 2508781973890bc187fb484a5f7f0e2d 493 Pfam PF00982 Glycosyltransferase family 20 18 485 3.0E-159 T 06-07-2017 IPR001830 Glycosyl transferase, family 20 GO:0003824|GO:0005992 BWK49_RS03650 2508781973890bc187fb484a5f7f0e2d 493 SUPERFAMILY SSF53756 17 487 4.5E-146 T 06-07-2017 BWK49_RS03650 2508781973890bc187fb484a5f7f0e2d 493 Gene3D G3DSA:3.40.50.2000 273 469 1.2E-75 T 06-07-2017 BWK49_RS15105 79e2fbf3985ffebe63dcb4ebf736a43f 110 PIRSF PIRSF018579 1 110 1.1E-46 T 06-07-2017 IPR009709 Protein of unknown function DUF1290 BWK49_RS15105 79e2fbf3985ffebe63dcb4ebf736a43f 110 Pfam PF06947 Protein of unknown function (DUF1290) 21 108 6.3E-33 T 06-07-2017 IPR009709 Protein of unknown function DUF1290 BWK49_RS14350 a30b236b90ac7a20d884a2ac47efa9f6 265 SUPERFAMILY SSF51445 63 196 4.84E-7 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily BWK49_RS14350 a30b236b90ac7a20d884a2ac47efa9f6 265 Pfam PF08924 Domain of unknown function (DUF1906) 59 186 3.9E-25 T 06-07-2017 IPR015020 Protein of unknown function DUF1906 BWK49_RS14350 a30b236b90ac7a20d884a2ac47efa9f6 265 Gene3D G3DSA:3.20.20.80 61 219 1.0E-10 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 BWK49_RS17035 92f96fc7d557375386f1f0bcbffefa9a 221 Gene3D G3DSA:1.10.357.10 12 202 7.3E-26 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS17035 92f96fc7d557375386f1f0bcbffefa9a 221 SUPERFAMILY SSF46689 15 88 9.75E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS17035 92f96fc7d557375386f1f0bcbffefa9a 221 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 4.6E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS17035 92f96fc7d557375386f1f0bcbffefa9a 221 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 4.6E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS17035 92f96fc7d557375386f1f0bcbffefa9a 221 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 69 1.5E-13 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS20395 51b3469ae2fb4fa7223d6341fedda7c8 257 Pfam PF02585 GlcNAc-PI de-N-acetylase 6 137 3.7E-20 T 06-07-2017 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 BWK49_RS20395 51b3469ae2fb4fa7223d6341fedda7c8 257 SUPERFAMILY SSF102588 2 227 7.32E-45 T 06-07-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 BWK49_RS20395 51b3469ae2fb4fa7223d6341fedda7c8 257 Gene3D G3DSA:3.40.50.10320 2 241 2.2E-49 T 06-07-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 BWK49_RS16835 b222b34a063e87dc392686f445f2d0a8 275 TIGRFAM TIGR03856 F420_MSMEG_2906: probable F420-dependent oxidoreductase, MSMEG_2906 family 9 272 7.0E-118 T 06-07-2017 IPR022480 F420-dependent oxidoreductase, MSMEG2906 BWK49_RS16835 b222b34a063e87dc392686f445f2d0a8 275 SUPERFAMILY SSF51679 12 237 7.46E-40 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS16835 b222b34a063e87dc392686f445f2d0a8 275 Pfam PF00296 Luciferase-like monooxygenase 16 230 3.2E-26 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS16835 b222b34a063e87dc392686f445f2d0a8 275 Gene3D G3DSA:3.20.20.30 5 232 5.0E-40 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS25165 f64ae122e035c4967add867519b45d01 449 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 251 287 - T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 BWK49_RS25165 f64ae122e035c4967add867519b45d01 449 Gene3D G3DSA:3.40.640.10 87 330 2.3E-76 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 BWK49_RS25165 f64ae122e035c4967add867519b45d01 449 Pfam PF00202 Aminotransferase class-III 51 434 9.6E-93 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 BWK49_RS25165 f64ae122e035c4967add867519b45d01 449 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 21 434 4.0E-187 T 06-07-2017 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 BWK49_RS25165 f64ae122e035c4967add867519b45d01 449 Gene3D G3DSA:3.90.1150.10 17 86 4.7E-34 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 BWK49_RS25165 f64ae122e035c4967add867519b45d01 449 Gene3D G3DSA:3.90.1150.10 335 437 4.7E-34 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 BWK49_RS25165 f64ae122e035c4967add867519b45d01 449 SUPERFAMILY SSF53383 19 437 1.28E-113 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase BWK49_RS25165 f64ae122e035c4967add867519b45d01 449 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 20 441 95.557 T 06-07-2017 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 BWK49_RS24715 b6602e10d359f64fb09f16e497403d2d 315 Gene3D G3DSA:3.40.50.150 83 219 1.7E-12 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS24715 b6602e10d359f64fb09f16e497403d2d 315 SUPERFAMILY SSF53335 15 310 1.11E-77 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS24715 b6602e10d359f64fb09f16e497403d2d 315 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 17 292 1.0E-83 T 06-07-2017 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 BWK49_RS24715 b6602e10d359f64fb09f16e497403d2d 315 Pfam PF04072 Leucine carboxyl methyltransferase 19 204 1.0E-60 T 06-07-2017 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 BWK49_RS24650 46710078f90193d9c85cce30de10d669 231 SUPERFAMILY SSF52096 4 222 2.31E-41 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS24650 46710078f90193d9c85cce30de10d669 231 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 207 2.3E-27 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 BWK49_RS24650 46710078f90193d9c85cce30de10d669 231 Gene3D G3DSA:3.90.226.10 4 221 2.6E-34 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS14475 51a08925a8ed0098aed9a3bbcd3dac0f 300 SUPERFAMILY SSF51735 2 293 1.59E-38 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS14475 51a08925a8ed0098aed9a3bbcd3dac0f 300 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 174 2.0E-16 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 BWK49_RS14475 51a08925a8ed0098aed9a3bbcd3dac0f 300 Gene3D G3DSA:3.40.50.720 5 289 5.3E-27 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS21815 d110fdb76b2904fc1ec57ff29c773978 261 Pfam PF00892 EamA-like transporter family 131 259 7.8E-10 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 BWK49_RS21815 d110fdb76b2904fc1ec57ff29c773978 261 SUPERFAMILY SSF103481 164 259 1.83E-10 T 06-07-2017 BWK49_RS21815 d110fdb76b2904fc1ec57ff29c773978 261 SUPERFAMILY SSF103481 23 114 1.05E-6 T 06-07-2017 BWK49_RS10560 c7b6ca3622529056e06a4a713168f3d2 466 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 1 457 14.556 T 06-07-2017 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 BWK49_RS10560 c7b6ca3622529056e06a4a713168f3d2 466 Pfam PF00361 Proton-conducting membrane transporter 119 406 1.5E-46 T 06-07-2017 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS00735 6dd8994c2e59e1d63016b19091effe88 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 5.2E-12 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS00735 6dd8994c2e59e1d63016b19091effe88 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 5.2E-12 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS00735 6dd8994c2e59e1d63016b19091effe88 200 SUPERFAMILY SSF46689 5 83 8.21E-22 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS00735 6dd8994c2e59e1d63016b19091effe88 200 Gene3D G3DSA:1.10.357.10 64 186 1.1E-18 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS00735 6dd8994c2e59e1d63016b19091effe88 200 Gene3D G3DSA:1.10.10.60 47 63 6.8E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS00735 6dd8994c2e59e1d63016b19091effe88 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 64 2.3E-18 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS00735 6dd8994c2e59e1d63016b19091effe88 200 Gene3D G3DSA:1.10.10.60 5 46 7.8E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS07220 90835725be250210c02475818a1a6761 316 SUPERFAMILY SSF51206 2 124 1.7E-20 T 06-07-2017 IPR018490 Cyclic nucleotide-binding-like BWK49_RS07220 90835725be250210c02475818a1a6761 316 ProSitePatterns PS00889 Cyclic nucleotide-binding domain signature 2. 70 87 - T 06-07-2017 IPR018488 Cyclic nucleotide-binding, conserved site BWK49_RS07220 90835725be250210c02475818a1a6761 316 SMART SM00100 3 123 5.5E-22 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain BWK49_RS07220 90835725be250210c02475818a1a6761 316 Pfam PF13302 Acetyltransferase (GNAT) domain 139 272 7.7E-8 T 06-07-2017 IPR000182 GNAT domain GO:0008080 BWK49_RS07220 90835725be250210c02475818a1a6761 316 Gene3D G3DSA:2.60.120.10 2 124 8.7E-22 T 06-07-2017 IPR014710 RmlC-like jelly roll fold BWK49_RS07220 90835725be250210c02475818a1a6761 316 Pfam PF00027 Cyclic nucleotide-binding domain 23 104 4.9E-13 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain BWK49_RS07220 90835725be250210c02475818a1a6761 316 SUPERFAMILY SSF55729 139 277 6.56E-17 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase BWK49_RS07220 90835725be250210c02475818a1a6761 316 Gene3D G3DSA:3.40.630.30 141 271 3.6E-15 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase BWK49_RS17255 8d9ca4fddf4930f0be0ae08e24b967ec 147 Pfam PF10825 Protein of unknown function (DUF2752) 55 102 8.1E-19 T 06-07-2017 IPR021215 Protein of unknown function DUF2752 BWK49_RS23915 91f466167a8bde16f7f4220d880b5f9d 346 TIGRFAM TIGR03559 F420_Rv3520c: probable F420-dependent oxidoreductase, Rv3520c family 2 324 4.8E-160 T 06-07-2017 IPR019951 F420-dependent oxidoreductase-predicted, Rv3520c BWK49_RS23915 91f466167a8bde16f7f4220d880b5f9d 346 Gene3D G3DSA:3.20.20.30 1 340 3.2E-67 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS23915 91f466167a8bde16f7f4220d880b5f9d 346 SUPERFAMILY SSF51679 1 340 1.83E-63 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS23915 91f466167a8bde16f7f4220d880b5f9d 346 Pfam PF00296 Luciferase-like monooxygenase 4 320 2.7E-74 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS00330 734b4c45718c18f74b0706124ea45b62 389 Gene3D G3DSA:3.40.50.300 81 335 8.8E-20 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS00330 734b4c45718c18f74b0706124ea45b62 389 SUPERFAMILY SSF52540 78 126 1.51E-30 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS00330 734b4c45718c18f74b0706124ea45b62 389 SUPERFAMILY SSF52540 198 352 1.51E-30 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS00330 734b4c45718c18f74b0706124ea45b62 389 Pfam PF13469 Sulfotransferase family 83 331 2.5E-28 T 06-07-2017 BWK49_RS28555 f64dd419b943a2a830799b560402e861 149 Gene3D G3DSA:1.10.1220.10 108 141 8.9E-4 T 06-07-2017 IPR013321 Arc-type ribbon-helix-helix GO:0006355 BWK49_RS28555 f64dd419b943a2a830799b560402e861 149 Gene3D G3DSA:1.10.1220.10 31 86 0.001 T 06-07-2017 IPR013321 Arc-type ribbon-helix-helix GO:0006355 BWK49_RS28555 f64dd419b943a2a830799b560402e861 149 SUPERFAMILY SSF47598 26 89 5.0E-5 T 06-07-2017 IPR010985 Ribbon-helix-helix GO:0006355 BWK49_RS28555 f64dd419b943a2a830799b560402e861 149 SUPERFAMILY SSF47598 103 146 1.89E-5 T 06-07-2017 IPR010985 Ribbon-helix-helix GO:0006355 BWK49_RS12415 656b9735e0444d3b35fb667d12aeeca8 312 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 10 302 1.8E-44 T 06-07-2017 IPR005218 Diacylglycerol/lipid kinase BWK49_RS12415 656b9735e0444d3b35fb667d12aeeca8 312 SUPERFAMILY SSF111331 9 304 1.26E-71 T 06-07-2017 IPR016064 NAD kinase/diacylglycerol kinase-like domain BWK49_RS12415 656b9735e0444d3b35fb667d12aeeca8 312 SMART SM00046 9 141 2.0E-4 T 06-07-2017 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 BWK49_RS12415 656b9735e0444d3b35fb667d12aeeca8 312 Gene3D G3DSA:3.40.50.10330 25 97 4.9E-5 T 06-07-2017 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 BWK49_RS12415 656b9735e0444d3b35fb667d12aeeca8 312 Pfam PF00781 Diacylglycerol kinase catalytic domain 10 132 2.9E-28 T 06-07-2017 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 BWK49_RS26565 a92ac1f151f9f0a35de354f2f5a61bf0 562 ProSitePatterns PS00455 Putative AMP-binding domain signature. 223 234 - T 06-07-2017 IPR020845 AMP-binding, conserved site BWK49_RS26565 a92ac1f151f9f0a35de354f2f5a61bf0 562 Gene3D G3DSA:3.40.50.980 68 228 2.3E-30 T 06-07-2017 BWK49_RS26565 a92ac1f151f9f0a35de354f2f5a61bf0 562 Pfam PF00501 AMP-binding enzyme 69 466 1.2E-77 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS26565 a92ac1f151f9f0a35de354f2f5a61bf0 562 SUPERFAMILY SSF56801 68 561 9.94E-128 T 06-07-2017 BWK49_RS26565 a92ac1f151f9f0a35de354f2f5a61bf0 562 Gene3D G3DSA:3.30.300.30 461 560 1.2E-33 T 06-07-2017 BWK49_RS26565 a92ac1f151f9f0a35de354f2f5a61bf0 562 Gene3D G3DSA:2.30.38.10 388 456 5.5E-13 T 06-07-2017 BWK49_RS26565 a92ac1f151f9f0a35de354f2f5a61bf0 562 Pfam PF13193 AMP-binding enzyme C-terminal domain 475 550 9.1E-21 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS26565 a92ac1f151f9f0a35de354f2f5a61bf0 562 Gene3D G3DSA:3.40.50.980 229 381 5.9E-32 T 06-07-2017 BWK49_RS08525 abd9c1bef049a59d052805af6e641e8f 257 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 87 243 5.9E-32 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS08525 abd9c1bef049a59d052805af6e641e8f 257 Pfam PF04542 Sigma-70 region 2 90 156 4.7E-22 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS08525 abd9c1bef049a59d052805af6e641e8f 257 Pfam PF08281 Sigma-70, region 4 189 239 8.1E-17 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS08525 abd9c1bef049a59d052805af6e641e8f 257 Gene3D G3DSA:1.10.10.10 184 244 3.3E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS08525 abd9c1bef049a59d052805af6e641e8f 257 SUPERFAMILY SSF88946 86 174 1.37E-25 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS08525 abd9c1bef049a59d052805af6e641e8f 257 SUPERFAMILY SSF88659 166 245 2.8E-17 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 BWK49_RS08525 abd9c1bef049a59d052805af6e641e8f 257 Gene3D G3DSA:1.10.1740.10 79 178 1.4E-27 T 06-07-2017 BWK49_RS18395 9c3acbc8eea5613b7b046f2bb2df1367 161 ProSitePatterns PS01117 MarR-type HTH domain signature. 72 107 - T 06-07-2017 IPR023187 Transcriptional regulator MarR-type, conserved site BWK49_RS18395 9c3acbc8eea5613b7b046f2bb2df1367 161 SUPERFAMILY SSF46785 7 147 3.58E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS18395 9c3acbc8eea5613b7b046f2bb2df1367 161 SMART SM00347 36 134 1.3E-20 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 BWK49_RS18395 9c3acbc8eea5613b7b046f2bb2df1367 161 Gene3D G3DSA:1.10.10.10 5 146 2.1E-33 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS18395 9c3acbc8eea5613b7b046f2bb2df1367 161 Pfam PF01047 MarR family 41 98 5.6E-16 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 BWK49_RS04755 21397a4a018fcbcbc6b857ff5bedaaf3 266 Gene3D G3DSA:1.10.12.10 209 266 5.6E-18 T 06-07-2017 IPR014748 Crontonase, C-terminal BWK49_RS04755 21397a4a018fcbcbc6b857ff5bedaaf3 266 Gene3D G3DSA:3.90.226.10 16 203 5.5E-53 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS04755 21397a4a018fcbcbc6b857ff5bedaaf3 266 SUPERFAMILY SSF52096 14 266 1.76E-74 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS04755 21397a4a018fcbcbc6b857ff5bedaaf3 266 Pfam PF00378 Enoyl-CoA hydratase/isomerase 23 265 1.1E-52 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 BWK49_RS00260 778c30d6262a7ec12e298d65892a7580 394 Pfam PF10738 Probable lipoprotein LpqN 109 277 1.2E-62 T 06-07-2017 IPR019674 Lipoprotein LpqT, predicted BWK49_RS10055 c277b910d31ca665fc38eeaa79e001c6 291 SUPERFAMILY SSF52540 115 280 6.35E-34 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS10055 c277b910d31ca665fc38eeaa79e001c6 291 SUPERFAMILY SSF52540 40 88 6.35E-34 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS10055 c277b910d31ca665fc38eeaa79e001c6 291 Pfam PF07728 AAA domain (dynein-related subfamily) 46 194 7.5E-11 T 06-07-2017 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 BWK49_RS10055 c277b910d31ca665fc38eeaa79e001c6 291 SMART SM00382 42 205 1.6E-8 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS10055 c277b910d31ca665fc38eeaa79e001c6 291 Gene3D G3DSA:3.40.50.300 39 226 2.3E-30 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS10565 de374444a8212d7a8f73654eca6d60a7 496 Pfam PF00361 Proton-conducting membrane transporter 126 422 9.6E-63 T 06-07-2017 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS10565 de374444a8212d7a8f73654eca6d60a7 496 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 2 491 3.8E-146 T 06-07-2017 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS10565 de374444a8212d7a8f73654eca6d60a7 496 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 132 151 5.7E-26 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS10565 de374444a8212d7a8f73654eca6d60a7 496 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 386 412 5.7E-26 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS10565 de374444a8212d7a8f73654eca6d60a7 496 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 236 260 5.7E-26 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS10565 de374444a8212d7a8f73654eca6d60a7 496 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 162 186 5.7E-26 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS25845 1f4fd669e535b507da2c7e21ddf1cc81 142 Pfam PF10825 Protein of unknown function (DUF2752) 45 92 2.6E-18 T 06-07-2017 IPR021215 Protein of unknown function DUF2752 BWK49_RS22795 9b3e7d087a6a3172a1d68fb6d5f46a84 396 SUPERFAMILY SSF52540 86 136 2.8E-30 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS22795 9b3e7d087a6a3172a1d68fb6d5f46a84 396 SUPERFAMILY SSF52540 214 368 2.8E-30 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS22795 9b3e7d087a6a3172a1d68fb6d5f46a84 396 Pfam PF13469 Sulfotransferase family 90 341 2.6E-51 T 06-07-2017 BWK49_RS22795 9b3e7d087a6a3172a1d68fb6d5f46a84 396 Gene3D G3DSA:3.40.50.300 88 125 8.8E-13 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS22795 9b3e7d087a6a3172a1d68fb6d5f46a84 396 Gene3D G3DSA:3.40.50.300 189 190 8.8E-13 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS22795 9b3e7d087a6a3172a1d68fb6d5f46a84 396 Gene3D G3DSA:3.40.50.300 224 344 8.8E-13 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS02195 bbb45752df7b2cac9158f3fbe2b8078c 174 TIGRFAM TIGR03941 tRNA_deam_assoc: putative tRNA adenosine deaminase-associated protein 19 167 2.4E-50 T 06-07-2017 IPR023869 tRNA adenosine deaminase-associated protein, putative BWK49_RS16870 ee13221263832605a28c7e4468e91061 242 SUPERFAMILY SSF102215 13 233 2.48E-54 T 06-07-2017 IPR024087 Creatininase-like domain KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167 BWK49_RS16870 ee13221263832605a28c7e4468e91061 242 Gene3D G3DSA:3.40.50.10310 17 234 2.0E-60 T 06-07-2017 IPR024087 Creatininase-like domain KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167 BWK49_RS16870 ee13221263832605a28c7e4468e91061 242 Pfam PF02633 Creatinine amidohydrolase 16 233 3.6E-56 T 06-07-2017 IPR003785 Creatininase/formamide hydrolase KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167 BWK49_RS00195 b71acf23a1833316594538336492e38e 138 Pfam PF02467 Transcription factor WhiB 12 83 1.7E-12 T 06-07-2017 IPR003482 Transcription factor WhiB BWK49_RS00195 b71acf23a1833316594538336492e38e 138 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 88 15.831 T 06-07-2017 IPR003482 Transcription factor WhiB BWK49_RS25310 8f6c058e34380d464c3e2c99d5b57d49 354 SMART SM00563 140 259 9.0E-22 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 BWK49_RS25310 8f6c058e34380d464c3e2c99d5b57d49 354 PIRSF PIRSF016753 44 354 1.7E-119 T 06-07-2017 IPR016676 Phospholipid/glycerol acyltransferase, predicted BWK49_RS25310 8f6c058e34380d464c3e2c99d5b57d49 354 Gene3D G3DSA:3.40.1130.10 106 265 3.5E-5 T 06-07-2017 BWK49_RS25310 8f6c058e34380d464c3e2c99d5b57d49 354 Pfam PF01553 Acyltransferase 125 256 2.5E-18 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 BWK49_RS25310 8f6c058e34380d464c3e2c99d5b57d49 354 SUPERFAMILY SSF69593 90 346 3.27E-43 T 06-07-2017 BWK49_RS11100 1fd008796b430dfc2d1f434e2faa3793 371 SUPERFAMILY SSF51197 53 317 2.24E-41 T 06-07-2017 BWK49_RS11100 1fd008796b430dfc2d1f434e2faa3793 371 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 63 306 3.5E-24 T 06-07-2017 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 BWK49_RS11100 1fd008796b430dfc2d1f434e2faa3793 371 Gene3D G3DSA:3.60.130.10 52 317 3.4E-32 T 06-07-2017 BWK49_RS04825 cf63ddfbc2e596411036e01f70aacfff 521 SUPERFAMILY SSF51905 1 389 1.3E-53 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS04825 cf63ddfbc2e596411036e01f70aacfff 521 Gene3D G3DSA:3.50.50.60 318 462 7.9E-6 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS04825 cf63ddfbc2e596411036e01f70aacfff 521 Gene3D G3DSA:3.50.50.60 2 215 1.9E-53 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS04825 cf63ddfbc2e596411036e01f70aacfff 521 Pfam PF00743 Flavin-binding monooxygenase-like 7 213 9.4E-11 T 06-07-2017 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 BWK49_RS14020 66d66087b1e603762cd96e7ab5ae203f 223 PIRSF PIRSF033303 3 216 7.9E-54 T 06-07-2017 IPR014581 Uncharacterised conserved protein UCP033303 BWK49_RS14020 66d66087b1e603762cd96e7ab5ae203f 223 Pfam PF07040 Protein of unknown function (DUF1326) 18 199 1.9E-55 T 06-07-2017 IPR009758 Protein of unknown function DUF1326 BWK49_RS10835 e9697804901aec7f6f8d5b699af1057c 307 Gene3D G3DSA:3.40.50.720 1 92 9.1E-7 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS10780 ec75a83a91ce78ad9a122c020856bf1e 264 Pfam PF00106 short chain dehydrogenase 11 175 6.4E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS10780 ec75a83a91ce78ad9a122c020856bf1e 264 SUPERFAMILY SSF51735 11 233 3.14E-42 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS10780 ec75a83a91ce78ad9a122c020856bf1e 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 3.5E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS10780 ec75a83a91ce78ad9a122c020856bf1e 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 3.5E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS10780 ec75a83a91ce78ad9a122c020856bf1e 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 3.5E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS10780 ec75a83a91ce78ad9a122c020856bf1e 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 3.5E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS10780 ec75a83a91ce78ad9a122c020856bf1e 264 Gene3D G3DSA:3.40.50.720 11 237 8.1E-41 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS27950 b618f9ed4ce936e7a6d10700a0fea979 282 SUPERFAMILY SSF55781 223 275 1.62E-10 T 06-07-2017 IPR029016 GAF domain-like BWK49_RS27950 b618f9ed4ce936e7a6d10700a0fea979 282 SUPERFAMILY SSF55781 73 176 1.62E-10 T 06-07-2017 IPR029016 GAF domain-like BWK49_RS27950 b618f9ed4ce936e7a6d10700a0fea979 282 Pfam PF09339 IclR helix-turn-helix domain 2 49 9.9E-8 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 BWK49_RS27950 b618f9ed4ce936e7a6d10700a0fea979 282 SMART SM00346 1 86 0.0076 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 BWK49_RS27950 b618f9ed4ce936e7a6d10700a0fea979 282 Gene3D G3DSA:1.10.10.10 2 64 1.7E-10 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS27950 b618f9ed4ce936e7a6d10700a0fea979 282 SUPERFAMILY SSF46785 2 64 1.42E-7 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS27950 b618f9ed4ce936e7a6d10700a0fea979 282 Gene3D G3DSA:3.30.450.40 71 175 3.3E-15 T 06-07-2017 IPR029016 GAF domain-like BWK49_RS27950 b618f9ed4ce936e7a6d10700a0fea979 282 Gene3D G3DSA:3.30.450.40 222 272 3.3E-15 T 06-07-2017 IPR029016 GAF domain-like BWK49_RS21100 12fbf2c519741fc033c60cf24f4c03e8 414 Gene3D G3DSA:3.40.50.2000 187 372 4.3E-38 T 06-07-2017 BWK49_RS21100 12fbf2c519741fc033c60cf24f4c03e8 414 SUPERFAMILY SSF53756 2 392 1.49E-92 T 06-07-2017 BWK49_RS21100 12fbf2c519741fc033c60cf24f4c03e8 414 Pfam PF13439 Glycosyltransferase Family 4 15 204 2.9E-29 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 BWK49_RS21100 12fbf2c519741fc033c60cf24f4c03e8 414 Pfam PF00534 Glycosyl transferases group 1 213 372 6.5E-42 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 BWK49_RS17240 bbb7c0674c3465e62c0429e46ad1fcc6 465 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 144 439 2.8E-66 T 06-07-2017 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal BWK49_RS01895 c0732a5091bf69060c079175a7e46904 393 SUPERFAMILY SSF55961 165 392 1.65E-39 T 06-07-2017 BWK49_RS01895 c0732a5091bf69060c079175a7e46904 393 Gene3D G3DSA:3.90.380.10 155 391 6.3E-38 T 06-07-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 BWK49_RS01895 c0732a5091bf69060c079175a7e46904 393 Pfam PF00355 Rieske [2Fe-2S] domain 50 131 4.4E-15 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS01895 c0732a5091bf69060c079175a7e46904 393 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 106 126 3.6E-19 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS01895 c0732a5091bf69060c079175a7e46904 393 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 33 58 3.6E-19 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS01895 c0732a5091bf69060c079175a7e46904 393 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 187 209 3.6E-19 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS01895 c0732a5091bf69060c079175a7e46904 393 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 85 105 3.6E-19 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS01895 c0732a5091bf69060c079175a7e46904 393 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 148 174 3.6E-19 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS01895 c0732a5091bf69060c079175a7e46904 393 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 64 79 3.6E-19 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS01895 c0732a5091bf69060c079175a7e46904 393 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 195 359 3.1E-11 T 06-07-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 BWK49_RS01895 c0732a5091bf69060c079175a7e46904 393 SUPERFAMILY SSF50022 17 163 2.88E-39 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS01895 c0732a5091bf69060c079175a7e46904 393 Gene3D G3DSA:2.102.10.10 50 154 1.4E-21 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS06065 25f344943d92dda4951018cdb6809dc9 156 SUPERFAMILY SSF54427 11 148 1.66E-24 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS06065 25f344943d92dda4951018cdb6809dc9 156 Gene3D G3DSA:3.10.450.50 16 135 2.5E-22 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS06065 25f344943d92dda4951018cdb6809dc9 156 Pfam PF13577 SnoaL-like domain 14 124 2.1E-12 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain BWK49_RS16285 a1a79f14c4f1399ae8607235dec69018 467 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 1 459 14.595 T 06-07-2017 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 BWK49_RS16285 a1a79f14c4f1399ae8607235dec69018 467 Pfam PF00361 Proton-conducting membrane transporter 119 405 3.8E-47 T 06-07-2017 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS10870 efc8ee1c224fe50e0d63cea3a323c23f 161 SUPERFAMILY SSF54593 6 135 1.97E-13 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS10870 efc8ee1c224fe50e0d63cea3a323c23f 161 Gene3D G3DSA:3.10.180.10 4 133 1.7E-13 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS10870 efc8ee1c224fe50e0d63cea3a323c23f 161 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 112 6.2E-14 T 06-07-2017 BWK49_RS06440 d0c812fd67f273dbeda3c1ca8c1f2f52 106 Pfam PF05481 Mycobacterium 19 kDa lipoprotein antigen 1 106 3.8E-16 T 06-07-2017 IPR008691 19kDa lipoprotein antigen GO:0016020 BWK49_RS18015 2d160b83c09206672d2f2e08a9320b83 474 Pfam PF07690 Major Facilitator Superfamily 6 395 7.7E-44 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 BWK49_RS18015 2d160b83c09206672d2f2e08a9320b83 474 SUPERFAMILY SSF103473 2 186 4.05E-56 T 06-07-2017 IPR020846 Major facilitator superfamily domain BWK49_RS18015 2d160b83c09206672d2f2e08a9320b83 474 SUPERFAMILY SSF103473 234 435 4.05E-56 T 06-07-2017 IPR020846 Major facilitator superfamily domain BWK49_RS18015 2d160b83c09206672d2f2e08a9320b83 474 Gene3D G3DSA:1.20.1250.20 2 177 1.5E-27 T 06-07-2017 BWK49_RS18015 2d160b83c09206672d2f2e08a9320b83 474 Gene3D G3DSA:1.20.1250.20 248 443 1.4E-10 T 06-07-2017 BWK49_RS12615 76b8a52b8fad53f6e5717fcecd92568c 518 SUPERFAMILY SSF53474 83 152 5.67E-23 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS12615 76b8a52b8fad53f6e5717fcecd92568c 518 SUPERFAMILY SSF53474 346 505 5.67E-23 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS12615 76b8a52b8fad53f6e5717fcecd92568c 518 SUPERFAMILY SSF53474 198 252 5.67E-23 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS12615 76b8a52b8fad53f6e5717fcecd92568c 518 Gene3D G3DSA:3.40.50.1820 196 323 3.6E-56 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS12615 76b8a52b8fad53f6e5717fcecd92568c 518 Gene3D G3DSA:3.40.50.1820 68 150 3.6E-56 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS12615 76b8a52b8fad53f6e5717fcecd92568c 518 Gene3D G3DSA:3.40.50.1820 385 506 3.6E-56 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS12615 76b8a52b8fad53f6e5717fcecd92568c 518 Pfam PF00561 alpha/beta hydrolase fold 100 495 1.6E-82 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS14205 74b4b468459ee71fc4716b7aa191b0e6 227 Pfam PF11139 Sap, sulfolipid-1-addressing protein 9 219 3.8E-9 T 06-07-2017 IPR021315 Glycolipid exporter Gap/Sap BWK49_RS22715 85d78d6b3b617ef9fcae27a626c16790 266 Gene3D G3DSA:3.40.50.300 6 254 5.1E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS22715 85d78d6b3b617ef9fcae27a626c16790 266 SUPERFAMILY SSF52540 4 255 3.49E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS22715 85d78d6b3b617ef9fcae27a626c16790 266 Pfam PF13614 AAA domain 4 178 1.3E-54 T 06-07-2017 IPR025669 AAA domain BWK49_RS14980 62474fcb4b2d13e7f10a230e39f0dbfa 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 112 130 1.0E-9 T 06-07-2017 BWK49_RS14980 62474fcb4b2d13e7f10a230e39f0dbfa 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 172 190 1.0E-9 T 06-07-2017 BWK49_RS14980 62474fcb4b2d13e7f10a230e39f0dbfa 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 17 36 1.0E-9 T 06-07-2017 BWK49_RS14980 62474fcb4b2d13e7f10a230e39f0dbfa 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 302 324 1.0E-9 T 06-07-2017 BWK49_RS14980 62474fcb4b2d13e7f10a230e39f0dbfa 461 Gene3D G3DSA:3.50.50.60 13 116 1.7E-18 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS14980 62474fcb4b2d13e7f10a230e39f0dbfa 461 SUPERFAMILY SSF51905 13 350 1.22E-30 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS14980 62474fcb4b2d13e7f10a230e39f0dbfa 461 Gene3D G3DSA:3.50.50.60 117 347 1.1E-24 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS14980 62474fcb4b2d13e7f10a230e39f0dbfa 461 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 15 339 5.5E-59 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS14980 62474fcb4b2d13e7f10a230e39f0dbfa 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 16 38 5.2E-9 T 06-07-2017 BWK49_RS14980 62474fcb4b2d13e7f10a230e39f0dbfa 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 317 324 5.2E-9 T 06-07-2017 BWK49_RS14980 62474fcb4b2d13e7f10a230e39f0dbfa 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 172 197 5.2E-9 T 06-07-2017 BWK49_RS19485 cd0bcaf918a1f53e01737ba782cbcdfd 323 PIRSF PIRSF028754 19 322 1.1E-130 T 06-07-2017 IPR008492 Protein of unknown function DUF774 BWK49_RS19485 cd0bcaf918a1f53e01737ba782cbcdfd 323 Pfam PF09754 PAC2 family 42 258 1.1E-44 T 06-07-2017 IPR019151 Proteasome assembly chaperone 2 BWK49_RS19485 cd0bcaf918a1f53e01737ba782cbcdfd 323 SUPERFAMILY SSF159659 18 283 8.24E-89 T 06-07-2017 BWK49_RS19485 cd0bcaf918a1f53e01737ba782cbcdfd 323 Gene3D G3DSA:1.10.287.100 240 281 8.5E-19 T 06-07-2017 IPR013028 Transcription factor IIA, alpha subunit, N-terminal GO:0006367 BWK49_RS24670 9d190fdbe7358206d9ec1521d95abc7b 155 Hamap MF_00535 Cyanate hydratase [cynS]. 1 155 77.291 T 06-07-2017 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 BWK49_RS24670 9d190fdbe7358206d9ec1521d95abc7b 155 SUPERFAMILY SSF55234 84 150 7.59E-29 T 06-07-2017 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 BWK49_RS24670 9d190fdbe7358206d9ec1521d95abc7b 155 SUPERFAMILY SSF47413 4 81 3.26E-21 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 BWK49_RS24670 9d190fdbe7358206d9ec1521d95abc7b 155 PRINTS PR01693 Cyanase signature 136 146 1.3E-29 T 06-07-2017 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 BWK49_RS24670 9d190fdbe7358206d9ec1521d95abc7b 155 PRINTS PR01693 Cyanase signature 18 33 1.3E-29 T 06-07-2017 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 BWK49_RS24670 9d190fdbe7358206d9ec1521d95abc7b 155 PRINTS PR01693 Cyanase signature 87 101 1.3E-29 T 06-07-2017 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 BWK49_RS24670 9d190fdbe7358206d9ec1521d95abc7b 155 PRINTS PR01693 Cyanase signature 38 55 1.3E-29 T 06-07-2017 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 BWK49_RS24670 9d190fdbe7358206d9ec1521d95abc7b 155 PRINTS PR01693 Cyanase signature 105 121 1.3E-29 T 06-07-2017 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 BWK49_RS24670 9d190fdbe7358206d9ec1521d95abc7b 155 SMART SM01116 79 150 4.0E-46 T 06-07-2017 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 BWK49_RS24670 9d190fdbe7358206d9ec1521d95abc7b 155 TIGRFAM TIGR00673 cynS: cyanase 9 149 1.2E-51 T 06-07-2017 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 BWK49_RS24670 9d190fdbe7358206d9ec1521d95abc7b 155 Pfam PF02560 Cyanate lyase C-terminal domain 83 149 4.5E-34 T 06-07-2017 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 BWK49_RS24670 9d190fdbe7358206d9ec1521d95abc7b 155 PIRSF PIRSF001263 2 151 2.1E-51 T 06-07-2017 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 BWK49_RS24670 9d190fdbe7358206d9ec1521d95abc7b 155 Gene3D G3DSA:3.30.1160.10 85 150 1.1E-34 T 06-07-2017 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 BWK49_RS24670 9d190fdbe7358206d9ec1521d95abc7b 155 Gene3D G3DSA:1.10.260.40 4 83 2.4E-30 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 BWK49_RS14435 b8572c3e1cfaa6f5d5acb81e396f464b 282 Gene3D G3DSA:2.60.120.200 41 282 1.7E-47 T 06-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain BWK49_RS14435 b8572c3e1cfaa6f5d5acb81e396f464b 282 SUPERFAMILY SSF49899 40 282 3.3E-46 T 06-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain BWK49_RS14435 b8572c3e1cfaa6f5d5acb81e396f464b 282 Pfam PF00722 Glycosyl hydrolases family 16 102 221 2.9E-16 T 06-07-2017 IPR000757 Glycoside hydrolase family 16 GO:0004553|GO:0005975 BWK49_RS04940 c093914ff22bd7e5e4caa2f6189ed8b3 375 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 12 300 2.5E-81 T 06-07-2017 IPR005693 Virulence factor Mce protein BWK49_RS04940 c093914ff22bd7e5e4caa2f6189ed8b3 375 Pfam PF02470 MlaD protein 42 115 7.8E-13 T 06-07-2017 IPR003399 Mce/MlaD BWK49_RS27260 32a816bbb5a171eaa584112c0a54b03f 346 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 148 299 9.3E-7 T 06-07-2017 IPR024516 Mammalian cell entry, C-terminal BWK49_RS27260 32a816bbb5a171eaa584112c0a54b03f 346 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 9 296 7.8E-85 T 06-07-2017 IPR005693 Virulence factor Mce protein BWK49_RS27260 32a816bbb5a171eaa584112c0a54b03f 346 Pfam PF02470 MlaD protein 38 112 2.7E-17 T 06-07-2017 IPR003399 Mce/MlaD BWK49_RS20570 7dc55386434794251a7ace743c4ca03b 93 Pfam PF07371 Protein of unknown function (DUF1490) 1 87 3.2E-36 T 06-07-2017 IPR009963 Protein of unknown function DUF1490 BWK49_RS20570 7dc55386434794251a7ace743c4ca03b 93 ProDom PD020015 MB2016C IRON REGULATED MB3297 RV1993C/MT2049 RV0968/MT0996 IRP10 ML0748 MB0993 13 77 4.0E-18 T 06-07-2017 IPR009963 Protein of unknown function DUF1490 BWK49_RS16105 7dc55386434794251a7ace743c4ca03b 93 Pfam PF07371 Protein of unknown function (DUF1490) 1 87 3.2E-36 T 06-07-2017 IPR009963 Protein of unknown function DUF1490 BWK49_RS16105 7dc55386434794251a7ace743c4ca03b 93 ProDom PD020015 MB2016C IRON REGULATED MB3297 RV1993C/MT2049 RV0968/MT0996 IRP10 ML0748 MB0993 13 77 4.0E-18 T 06-07-2017 IPR009963 Protein of unknown function DUF1490 BWK49_RS21230 c7a50b7406ef4690432571d04a52b9b3 245 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 164 198 4.5E-6 T 06-07-2017 IPR001451 Hexapeptide repeat BWK49_RS21230 c7a50b7406ef4690432571d04a52b9b3 245 SUPERFAMILY SSF51161 34 218 2.08E-30 T 06-07-2017 IPR011004 Trimeric LpxA-like BWK49_RS21230 c7a50b7406ef4690432571d04a52b9b3 245 Gene3D G3DSA:2.160.10.10 59 239 3.5E-32 T 06-07-2017 BWK49_RS28070 0f6a71adf48c8fdf1bb4083df2b2b2ce 411 SUPERFAMILY SSF53474 72 368 2.01E-18 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS28070 0f6a71adf48c8fdf1bb4083df2b2b2ce 411 PIRSF PIRSF029171 4 408 2.2E-63 T 06-07-2017 IPR005152 Lipase, secreted GO:0004806|GO:0016042 KEGG: 00561+3.1.1.3|MetaCyc: PWY-6857 BWK49_RS28070 0f6a71adf48c8fdf1bb4083df2b2b2ce 411 Gene3D G3DSA:3.40.50.1820 72 235 3.1E-14 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS28070 0f6a71adf48c8fdf1bb4083df2b2b2ce 411 Gene3D G3DSA:3.40.50.1820 295 368 3.1E-14 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS28070 0f6a71adf48c8fdf1bb4083df2b2b2ce 411 Pfam PF03583 Secretory lipase 126 405 4.3E-60 T 06-07-2017 IPR005152 Lipase, secreted GO:0004806|GO:0016042 KEGG: 00561+3.1.1.3|MetaCyc: PWY-6857 BWK49_RS15875 514ea0b672bf1e835f7f8ce1d8d7e80d 373 Pfam PF00355 Rieske [2Fe-2S] domain 26 110 8.1E-19 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS15875 514ea0b672bf1e835f7f8ce1d8d7e80d 373 SUPERFAMILY SSF55961 124 362 7.42E-33 T 06-07-2017 BWK49_RS15875 514ea0b672bf1e835f7f8ce1d8d7e80d 373 SUPERFAMILY SSF50022 19 132 1.11E-30 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS15875 514ea0b672bf1e835f7f8ce1d8d7e80d 373 Gene3D G3DSA:2.102.10.10 24 138 8.0E-33 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS20040 95a2b75d32970df9527c71f77661972e 461 SUPERFAMILY SSF55931 126 459 2.16E-100 T 06-07-2017 BWK49_RS20040 95a2b75d32970df9527c71f77661972e 461 Gene3D G3DSA:3.30.590.10 129 448 7.6E-96 T 06-07-2017 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 BWK49_RS20040 95a2b75d32970df9527c71f77661972e 461 SMART SM01230 125 378 1.1E-95 T 06-07-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 BWK49_RS20040 95a2b75d32970df9527c71f77661972e 461 SUPERFAMILY SSF54368 16 124 2.88E-17 T 06-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 BWK49_RS20040 95a2b75d32970df9527c71f77661972e 461 Pfam PF00120 Glutamine synthetase, catalytic domain 126 455 1.6E-102 T 06-07-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 BWK49_RS20040 95a2b75d32970df9527c71f77661972e 461 Gene3D G3DSA:3.10.20.70 18 128 4.6E-9 T 06-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 BWK49_RS28065 4fda3679b570fb6604604682253ffebd 269 Gene3D G3DSA:3.20.20.370 73 264 2.8E-35 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 BWK49_RS28065 4fda3679b570fb6604604682253ffebd 269 SUPERFAMILY SSF88713 67 264 5.56E-39 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 BWK49_RS28065 4fda3679b570fb6604604682253ffebd 269 Pfam PF01522 Polysaccharide deacetylase 75 198 1.8E-22 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 BWK49_RS22160 170478724c6ad674a3af999b355c4df8 317 SUPERFAMILY SSF56645 5 166 2.62E-14 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS22160 170478724c6ad674a3af999b355c4df8 317 Gene3D G3DSA:2.40.110.10 80 157 1.2E-12 T 06-07-2017 BWK49_RS22160 170478724c6ad674a3af999b355c4df8 317 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 79 156 8.3E-9 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 BWK49_RS03815 0a67e2576c5cad4e1e7ffa5e582b2e26 249 SUPERFAMILY SSF51735 4 246 1.47E-80 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS03815 0a67e2576c5cad4e1e7ffa5e582b2e26 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 1.4E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS03815 0a67e2576c5cad4e1e7ffa5e582b2e26 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 1.4E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS03815 0a67e2576c5cad4e1e7ffa5e582b2e26 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.4E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS03815 0a67e2576c5cad4e1e7ffa5e582b2e26 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.4E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS03815 0a67e2576c5cad4e1e7ffa5e582b2e26 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 1.4E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS03815 0a67e2576c5cad4e1e7ffa5e582b2e26 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 1.4E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS03815 0a67e2576c5cad4e1e7ffa5e582b2e26 249 Gene3D G3DSA:3.40.50.720 2 246 8.0E-81 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS03815 0a67e2576c5cad4e1e7ffa5e582b2e26 249 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 244 5.2E-65 T 06-07-2017 BWK49_RS03815 0a67e2576c5cad4e1e7ffa5e582b2e26 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 4.2E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS03815 0a67e2576c5cad4e1e7ffa5e582b2e26 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 4.2E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS03815 0a67e2576c5cad4e1e7ffa5e582b2e26 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 4.2E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS17490 8032deb556aaed3d699749cb0b3fa282 427 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 54 67 - T 06-07-2017 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 BWK49_RS17490 8032deb556aaed3d699749cb0b3fa282 427 SUPERFAMILY SSF53686 17 370 7.07E-90 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme BWK49_RS17490 8032deb556aaed3d699749cb0b3fa282 427 Gene3D G3DSA:3.40.50.1100 150 338 4.9E-58 T 06-07-2017 BWK49_RS17490 8032deb556aaed3d699749cb0b3fa282 427 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 29 320 5.4E-73 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme BWK49_RS17490 8032deb556aaed3d699749cb0b3fa282 427 TIGRFAM TIGR02079 THD1: threonine dehydratase 18 426 2.3E-191 T 06-07-2017 IPR011820 L-threonine dehydratase biosynthetic IlvA GO:0004794 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 BWK49_RS17490 8032deb556aaed3d699749cb0b3fa282 427 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 333 425 6.5E-28 T 06-07-2017 IPR001721 ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 BWK49_RS17490 8032deb556aaed3d699749cb0b3fa282 427 Gene3D G3DSA:3.40.50.1100 63 149 8.8E-25 T 06-07-2017 BWK49_RS08775 d509da7dfdb938a1a5e72fe103e98cda 544 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 104 464 1.1E-49 T 06-07-2017 IPR000914 Solute-binding protein family 5 domain BWK49_RS08775 d509da7dfdb938a1a5e72fe103e98cda 544 SUPERFAMILY SSF53850 39 541 6.7E-83 T 06-07-2017 BWK49_RS08775 d509da7dfdb938a1a5e72fe103e98cda 544 Gene3D G3DSA:3.40.190.10 172 303 1.7E-21 T 06-07-2017 BWK49_RS08775 d509da7dfdb938a1a5e72fe103e98cda 544 Gene3D G3DSA:3.10.105.10 304 513 2.6E-41 T 06-07-2017 BWK49_RS08775 d509da7dfdb938a1a5e72fe103e98cda 544 Gene3D G3DSA:3.90.76.10 92 171 9.6E-8 T 06-07-2017 BWK49_RS26110 776fc9a00031722d111ccd7329bb89d0 131 SMART SM00422 16 85 1.6E-27 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 BWK49_RS26110 776fc9a00031722d111ccd7329bb89d0 131 Pfam PF13411 MerR HTH family regulatory protein 18 83 5.8E-17 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 BWK49_RS26110 776fc9a00031722d111ccd7329bb89d0 131 Gene3D G3DSA:1.10.1660.10 18 110 3.7E-24 T 06-07-2017 BWK49_RS26110 776fc9a00031722d111ccd7329bb89d0 131 SUPERFAMILY SSF46955 17 107 3.07E-21 T 06-07-2017 IPR009061 Putative DNA-binding domain BWK49_RS18615 197b56f1bd579fe96a27b0bb986c091d 170 Pfam PF03652 Holliday junction resolvase 23 156 2.6E-41 T 06-07-2017 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 BWK49_RS18615 197b56f1bd579fe96a27b0bb986c091d 170 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 22 158 22.06 T 06-07-2017 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 BWK49_RS18615 197b56f1bd579fe96a27b0bb986c091d 170 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 25 155 5.7E-26 T 06-07-2017 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 BWK49_RS18615 197b56f1bd579fe96a27b0bb986c091d 170 Gene3D G3DSA:3.30.420.140 21 160 8.8E-46 T 06-07-2017 IPR006641 YqgF/RNase H-like domain GO:0006139 BWK49_RS18615 197b56f1bd579fe96a27b0bb986c091d 170 SMART SM00732 22 123 5.4E-26 T 06-07-2017 IPR006641 YqgF/RNase H-like domain GO:0006139 BWK49_RS18615 197b56f1bd579fe96a27b0bb986c091d 170 SUPERFAMILY SSF53098 22 157 7.89E-34 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS14310 48551b144dd14c086ae29a0d3f3ab466 465 SUPERFAMILY SSF140459 2 174 1.91E-64 T 06-07-2017 BWK49_RS14310 48551b144dd14c086ae29a0d3f3ab466 465 Pfam PF00823 PPE family 5 161 8.5E-63 T 06-07-2017 IPR000030 PPE family BWK49_RS14310 48551b144dd14c086ae29a0d3f3ab466 465 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 314 388 5.0E-13 T 06-07-2017 IPR022171 PPE family, C-terminal BWK49_RS14310 48551b144dd14c086ae29a0d3f3ab466 465 Pfam PF09851 Short C-terminal domain 437 463 4.7E-8 T 06-07-2017 IPR018649 SHOCT domain BWK49_RS21115 88e0388d56589c6ecc530a631ba78536 227 Gene3D G3DSA:2.40.180.10 169 224 1.0E-4 T 06-07-2017 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 BWK49_RS21115 88e0388d56589c6ecc530a631ba78536 227 SUPERFAMILY SSF56634 15 223 7.85E-6 T 06-07-2017 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 BWK49_RS27275 83c709866ebc612c8fae410b7db6400b 271 Pfam PF02405 Permease MlaE 52 262 7.2E-57 T 06-07-2017 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 BWK49_RS12705 818bb8c09ecf4971dbb235263035b2e5 73 Pfam PF12728 Helix-turn-helix domain 21 63 3.7E-9 T 06-07-2017 BWK49_RS12705 818bb8c09ecf4971dbb235263035b2e5 73 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 21 63 4.7E-11 T 06-07-2017 IPR010093 SinI-like, DNA-binding domain GO:0003677 BWK49_RS12705 818bb8c09ecf4971dbb235263035b2e5 73 SUPERFAMILY SSF46955 20 65 1.54E-7 T 06-07-2017 IPR009061 Putative DNA-binding domain BWK49_RS12620 f411c5d6da016bc4f4efaf41b632a884 520 Pfam PF00561 alpha/beta hydrolase fold 105 495 5.2E-63 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS12620 f411c5d6da016bc4f4efaf41b632a884 520 Gene3D G3DSA:3.40.50.1820 202 325 3.6E-54 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS12620 f411c5d6da016bc4f4efaf41b632a884 520 Gene3D G3DSA:3.40.50.1820 72 156 3.6E-54 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS12620 f411c5d6da016bc4f4efaf41b632a884 520 Gene3D G3DSA:3.40.50.1820 385 506 3.6E-54 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS12620 f411c5d6da016bc4f4efaf41b632a884 520 SUPERFAMILY SSF53474 104 154 1.21E-20 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS12620 f411c5d6da016bc4f4efaf41b632a884 520 SUPERFAMILY SSF53474 200 492 1.21E-20 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS20795 1371af6076331f538bd1445797ceec94 147 SUPERFAMILY SSF54427 6 143 1.7E-26 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS20795 1371af6076331f538bd1445797ceec94 147 Gene3D G3DSA:3.10.450.50 6 137 5.8E-21 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS20795 1371af6076331f538bd1445797ceec94 147 Pfam PF13577 SnoaL-like domain 6 131 2.7E-15 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain BWK49_RS22590 17219af398dc560a35e28fa526f19f26 314 Pfam PF12833 Helix-turn-helix domain 230 308 1.5E-20 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 BWK49_RS22590 17219af398dc560a35e28fa526f19f26 314 SMART SM00342 224 306 8.4E-22 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 BWK49_RS22590 17219af398dc560a35e28fa526f19f26 314 Pfam PF01965 DJ-1/PfpI family 2 168 2.6E-25 T 06-07-2017 IPR002818 DJ-1/PfpI BWK49_RS22590 17219af398dc560a35e28fa526f19f26 314 SUPERFAMILY SSF52317 2 188 1.92E-48 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like BWK49_RS22590 17219af398dc560a35e28fa526f19f26 314 SUPERFAMILY SSF46689 210 257 1.76E-6 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS22590 17219af398dc560a35e28fa526f19f26 314 Gene3D G3DSA:1.10.10.60 262 309 7.2E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS22590 17219af398dc560a35e28fa526f19f26 314 Gene3D G3DSA:3.40.50.880 2 212 8.7E-56 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like BWK49_RS22590 17219af398dc560a35e28fa526f19f26 314 SUPERFAMILY SSF46689 260 310 5.73E-8 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS22590 17219af398dc560a35e28fa526f19f26 314 Gene3D G3DSA:1.10.10.60 213 261 1.4E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS06590 b94cda5301c93ee646af9125a6f742a8 92 Pfam PF02597 ThiS family 15 92 3.9E-14 T 06-07-2017 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 BWK49_RS06590 b94cda5301c93ee646af9125a6f742a8 92 SUPERFAMILY SSF54285 12 90 1.74E-15 T 06-07-2017 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp BWK49_RS06590 b94cda5301c93ee646af9125a6f742a8 92 Gene3D G3DSA:3.10.20.30 12 92 4.1E-21 T 06-07-2017 IPR012675 Beta-grasp domain BWK49_RS19180 254695a81ab459c22e420cc7aacf25d4 424 Pfam PF04909 Amidohydrolase 77 371 1.7E-29 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 BWK49_RS19180 254695a81ab459c22e420cc7aacf25d4 424 Gene3D G3DSA:3.20.20.140 13 373 5.2E-54 T 06-07-2017 BWK49_RS19180 254695a81ab459c22e420cc7aacf25d4 424 SUPERFAMILY SSF51556 11 372 4.99E-60 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS14100 93871f6476fdd3b5d36e95e60e661093 249 SUPERFAMILY SSF53474 28 219 2.21E-44 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS14100 93871f6476fdd3b5d36e95e60e661093 249 SMART SM01110 27 219 1.2E-95 T 06-07-2017 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 BWK49_RS14100 93871f6476fdd3b5d36e95e60e661093 249 Gene3D G3DSA:3.40.50.1820 28 219 2.7E-55 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS14100 93871f6476fdd3b5d36e95e60e661093 249 Pfam PF01083 Cutinase 29 218 4.9E-45 T 06-07-2017 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 BWK49_RS16935 f0088cf85cbf7a3c5e1795841f0308c9 353 SUPERFAMILY SSF53901 3 352 1.1E-52 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS16935 f0088cf85cbf7a3c5e1795841f0308c9 353 Pfam PF02797 Chalcone and stilbene synthases, C-terminal domain 219 351 7.5E-16 T 06-07-2017 IPR012328 Chalcone/stilbene synthase, C-terminal BWK49_RS16935 f0088cf85cbf7a3c5e1795841f0308c9 353 Gene3D G3DSA:3.40.47.10 212 352 3.6E-34 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS16935 f0088cf85cbf7a3c5e1795841f0308c9 353 Pfam PF00195 Chalcone and stilbene synthases, N-terminal domain 9 197 1.5E-22 T 06-07-2017 IPR001099 Chalcone/stilbene synthase, N-terminal BWK49_RS16935 f0088cf85cbf7a3c5e1795841f0308c9 353 PIRSF PIRSF000451 1 353 9.6E-115 T 06-07-2017 IPR011141 Polyketide synthase, type III GO:0009058|GO:0016747 BWK49_RS16935 f0088cf85cbf7a3c5e1795841f0308c9 353 Gene3D G3DSA:3.40.47.10 3 205 1.4E-52 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS08595 70446b0a19b1109869f6c4032e808d55 197 Pfam PF05076 Suppressor of fused protein (SUFU) 30 191 6.6E-32 T 06-07-2017 IPR020941 Suppressor of fused-like domain Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5610787|Reactome: R-HSA-5632684 BWK49_RS13315 538257df73e6e7894f6b11c8991358ca 351 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 27 302 5.2E-45 T 06-07-2017 IPR005693 Virulence factor Mce protein BWK49_RS13315 538257df73e6e7894f6b11c8991358ca 351 Pfam PF02470 MlaD protein 51 125 4.9E-14 T 06-07-2017 IPR003399 Mce/MlaD BWK49_RS03860 8b5b3b9d7e4767358f25c0e74d834f6e 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 3.9E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS03860 8b5b3b9d7e4767358f25c0e74d834f6e 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 3.9E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS03860 8b5b3b9d7e4767358f25c0e74d834f6e 205 Gene3D G3DSA:1.10.357.10 10 193 7.5E-25 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS03860 8b5b3b9d7e4767358f25c0e74d834f6e 205 SUPERFAMILY SSF46689 7 76 2.77E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS03860 8b5b3b9d7e4767358f25c0e74d834f6e 205 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 61 5.9E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS07650 7d5012a45b6faf4775f87bce73b91e32 157 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 7 155 3.7E-16 T 06-07-2017 IPR019587 Polyketide cyclase/dehydrase BWK49_RS07650 7d5012a45b6faf4775f87bce73b91e32 157 SUPERFAMILY SSF55961 10 155 4.5E-14 T 06-07-2017 BWK49_RS07650 7d5012a45b6faf4775f87bce73b91e32 157 Gene3D G3DSA:3.30.530.20 40 155 3.6E-7 T 06-07-2017 IPR023393 START-like domain BWK49_RS06530 945a9f3980cd6ab66963e9d7b7e33855 164 Pfam PF08592 Domain of unknown function (DUF1772) 22 159 1.9E-17 T 06-07-2017 IPR013901 Protein of unknown function DUF1772 BWK49_RS15145 f9682edae04bdec7d0dce91f7667cce1 233 SUPERFAMILY SSF48498 92 227 5.16E-31 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS15145 f9682edae04bdec7d0dce91f7667cce1 233 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 64 1.2E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS15145 f9682edae04bdec7d0dce91f7667cce1 233 SUPERFAMILY SSF46689 10 82 2.06E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS15145 f9682edae04bdec7d0dce91f7667cce1 233 Gene3D G3DSA:1.10.357.10 8 230 2.7E-44 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS04295 e072d9cebf60b34dc7363a1765938bff 1767 Gene3D G3DSA:3.40.50.150 101 295 1.1E-30 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS04295 e072d9cebf60b34dc7363a1765938bff 1767 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 125 139 1.1E-5 T 06-07-2017 BWK49_RS04295 e072d9cebf60b34dc7363a1765938bff 1767 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 182 194 1.1E-5 T 06-07-2017 BWK49_RS04295 e072d9cebf60b34dc7363a1765938bff 1767 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 207 231 1.1E-5 T 06-07-2017 BWK49_RS04295 e072d9cebf60b34dc7363a1765938bff 1767 Gene3D G3DSA:3.40.50.300 1017 1052 2.5E-17 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS04295 e072d9cebf60b34dc7363a1765938bff 1767 Gene3D G3DSA:3.40.50.300 848 959 2.5E-17 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS04295 e072d9cebf60b34dc7363a1765938bff 1767 Gene3D G3DSA:3.40.50.300 1089 1113 2.5E-17 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS04295 e072d9cebf60b34dc7363a1765938bff 1767 SUPERFAMILY SSF52540 1309 1440 1.06E-15 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS04295 e072d9cebf60b34dc7363a1765938bff 1767 SMART SM00487 848 1089 0.0024 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain BWK49_RS04295 e072d9cebf60b34dc7363a1765938bff 1767 Gene3D G3DSA:3.40.50.300 1305 1409 9.9E-11 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS04295 e072d9cebf60b34dc7363a1765938bff 1767 SUPERFAMILY SSF53335 89 284 8.05E-28 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS04295 e072d9cebf60b34dc7363a1765938bff 1767 SUPERFAMILY SSF52540 811 961 2.22E-21 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS04295 e072d9cebf60b34dc7363a1765938bff 1767 SUPERFAMILY SSF52540 1018 1040 2.22E-21 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS04295 e072d9cebf60b34dc7363a1765938bff 1767 SUPERFAMILY SSF52540 1087 1119 2.22E-21 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS04095 736c021553b1cd1344dc48621dbf51a8 100 Pfam PF07210 Protein of unknown function (DUF1416) 2 99 8.8E-43 T 06-07-2017 IPR010814 Protein of unknown function DUF1416 BWK49_RS04095 736c021553b1cd1344dc48621dbf51a8 100 SUPERFAMILY SSF49464 23 75 5.49E-8 T 06-07-2017 IPR008969 Carboxypeptidase-like, regulatory domain BWK49_RS04095 736c021553b1cd1344dc48621dbf51a8 100 Gene3D G3DSA:2.60.40.1120 23 74 1.5E-6 T 06-07-2017 IPR014766 Carboxypeptidase, regulatory domain BWK49_RS01705 ca0d17874d9e49dad6a30a94951320c7 201 Gene3D G3DSA:3.10.450.50 17 201 1.4E-63 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS01705 ca0d17874d9e49dad6a30a94951320c7 201 SUPERFAMILY SSF54427 19 201 1.09E-42 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS01705 ca0d17874d9e49dad6a30a94951320c7 201 Pfam PF00866 Ring hydroxylating beta subunit 51 193 1.7E-41 T 06-07-2017 IPR000391 Ring-hydroxylating dioxygenase beta subunit GO:0003824|GO:0006725|GO:0055114 BWK49_RS01975 ca0d17874d9e49dad6a30a94951320c7 201 Gene3D G3DSA:3.10.450.50 17 201 1.4E-63 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS01975 ca0d17874d9e49dad6a30a94951320c7 201 SUPERFAMILY SSF54427 19 201 1.09E-42 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS01975 ca0d17874d9e49dad6a30a94951320c7 201 Pfam PF00866 Ring hydroxylating beta subunit 51 193 1.7E-41 T 06-07-2017 IPR000391 Ring-hydroxylating dioxygenase beta subunit GO:0003824|GO:0006725|GO:0055114 BWK49_RS20385 f43c6ad43ce246c7a3721c1ae616933a 97 ProSitePatterns PS00151 Acylphosphatase signature 2. 36 52 - T 06-07-2017 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 BWK49_RS20385 f43c6ad43ce246c7a3721c1ae616933a 97 SUPERFAMILY SSF54975 6 94 2.11E-23 T 06-07-2017 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 BWK49_RS20385 f43c6ad43ce246c7a3721c1ae616933a 97 Pfam PF00708 Acylphosphatase 7 94 8.8E-23 T 06-07-2017 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 BWK49_RS20385 f43c6ad43ce246c7a3721c1ae616933a 97 Gene3D G3DSA:3.30.70.100 7 94 1.9E-26 T 06-07-2017 BWK49_RS20385 f43c6ad43ce246c7a3721c1ae616933a 97 ProSitePatterns PS00150 Acylphosphatase signature 1. 12 22 - T 06-07-2017 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 BWK49_RS17640 d4839f770c65e56b2cc9a6030e67168a 246 Pfam PF01061 ABC-2 type transporter 6 210 3.3E-15 T 06-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 BWK49_RS17640 d4839f770c65e56b2cc9a6030e67168a 246 PIRSF PIRSF006648 2 246 5.7E-66 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 BWK49_RS09720 9d9912f9f6d479022e7a8cd95dd476e4 218 Gene3D G3DSA:1.10.357.10 72 185 1.7E-27 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS09720 9d9912f9f6d479022e7a8cd95dd476e4 218 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 43 1.6E-12 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS09720 9d9912f9f6d479022e7a8cd95dd476e4 218 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 51 74 1.6E-12 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS09720 9d9912f9f6d479022e7a8cd95dd476e4 218 Gene3D G3DSA:1.10.10.60 17 71 1.2E-20 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS09720 9d9912f9f6d479022e7a8cd95dd476e4 218 Pfam PF00440 Bacterial regulatory proteins, tetR family 30 76 2.1E-18 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS09720 9d9912f9f6d479022e7a8cd95dd476e4 218 SUPERFAMILY SSF46689 17 98 7.98E-19 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS09720 9d9912f9f6d479022e7a8cd95dd476e4 218 SUPERFAMILY SSF48498 97 189 1.61E-9 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS13840 66059cdce80623b598171521612e1fe7 304 Gene3D G3DSA:1.20.1080.10 59 298 4.9E-41 T 06-07-2017 IPR023271 Aquaporin-like Reactome: R-HSA-432047 BWK49_RS13840 66059cdce80623b598171521612e1fe7 304 Pfam PF01226 Formate/nitrite transporter 45 295 2.3E-41 T 06-07-2017 IPR000292 Formate/nitrite transporter GO:0005215|GO:0006810|GO:0016020 BWK49_RS05785 d3cc770bfa9eabc62b46b162fba94fa1 144 Pfam PF02310 B12 binding domain 4 114 8.9E-22 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 BWK49_RS05785 d3cc770bfa9eabc62b46b162fba94fa1 144 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 3 125 3.0E-44 T 06-07-2017 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 BWK49_RS05785 d3cc770bfa9eabc62b46b162fba94fa1 144 SUPERFAMILY SSF52242 3 124 3.4E-41 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 BWK49_RS05785 d3cc770bfa9eabc62b46b162fba94fa1 144 Gene3D G3DSA:3.40.50.280 3 125 6.2E-47 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 BWK49_RS27130 9494367ce58eba68b44d09ae408dc641 96 Pfam PF02583 Metal-sensitive transcriptional repressor 11 91 2.2E-31 T 06-07-2017 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 BWK49_RS21570 e050a174cf9ed13949af95ea1466efad 422 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 84 104 3.5E-6 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS21570 e050a174cf9ed13949af95ea1466efad 422 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 31 56 3.5E-6 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 BWK49_RS21570 e050a174cf9ed13949af95ea1466efad 422 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 189 412 4.7E-46 T 06-07-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 BWK49_RS21570 e050a174cf9ed13949af95ea1466efad 422 SUPERFAMILY SSF50022 12 166 1.83E-42 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS21570 e050a174cf9ed13949af95ea1466efad 422 Gene3D G3DSA:2.102.10.10 46 158 4.6E-25 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS21570 e050a174cf9ed13949af95ea1466efad 422 Pfam PF00355 Rieske [2Fe-2S] domain 47 137 6.5E-15 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS21570 e050a174cf9ed13949af95ea1466efad 422 SUPERFAMILY SSF55961 172 411 4.95E-42 T 06-07-2017 BWK49_RS21570 e050a174cf9ed13949af95ea1466efad 422 Gene3D G3DSA:3.90.380.10 159 395 8.1E-21 T 06-07-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 BWK49_RS04975 364f0b9b7d5387e0d90c3346cce1e3ce 268 PIRSF PIRSF007580 1 262 2.9E-67 T 06-07-2017 IPR016516 Uncharacterised conserved protein UCP07580 BWK49_RS04975 364f0b9b7d5387e0d90c3346cce1e3ce 268 Pfam PF10118 Predicted metal-dependent hydrolase 2 244 6.0E-70 T 06-07-2017 IPR016516 Uncharacterised conserved protein UCP07580 BWK49_RS05470 cd532d09295d7e8ab8877b4944a2acf2 313 SUPERFAMILY SSF47240 19 292 7.26E-48 T 06-07-2017 IPR009078 Ferritin-like superfamily BWK49_RS05470 cd532d09295d7e8ab8877b4944a2acf2 313 Pfam PF00268 Ribonucleotide reductase, small chain 29 238 8.5E-16 T 06-07-2017 IPR000358 Ribonucleotide reductase small subunit GO:0009186|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 BWK49_RS05470 cd532d09295d7e8ab8877b4944a2acf2 313 Gene3D G3DSA:1.10.620.20 27 277 4.8E-41 T 06-07-2017 IPR012348 Ribonucleotide reductase-related GO:0016491|GO:0055114 Reactome: R-HSA-499943 BWK49_RS02045 8c47ff84832e29971a60617be120dc64 123 Pfam PF13676 TIR domain 7 96 7.6E-8 T 06-07-2017 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 BWK49_RS02045 8c47ff84832e29971a60617be120dc64 123 SUPERFAMILY SSF52206 49 101 2.09E-7 T 06-07-2017 IPR015032 MTH538 TIR-like domain BWK49_RS02045 8c47ff84832e29971a60617be120dc64 123 Gene3D G3DSA:3.40.50.9200 7 101 1.9E-6 T 06-07-2017 IPR015032 MTH538 TIR-like domain BWK49_RS22890 79457222ace4df4a8b852d46547caeb1 266 Pfam PF07298 NnrU protein 65 245 6.8E-9 T 06-07-2017 IPR009915 NnrU domain BWK49_RS10900 a2e91a985be9c93780cace890fce7509 296 Gene3D G3DSA:3.30.450.40 230 290 5.3E-18 T 06-07-2017 IPR029016 GAF domain-like BWK49_RS10900 a2e91a985be9c93780cace890fce7509 296 Gene3D G3DSA:3.30.450.40 86 187 5.3E-18 T 06-07-2017 IPR029016 GAF domain-like BWK49_RS10900 a2e91a985be9c93780cace890fce7509 296 SUPERFAMILY SSF55781 235 289 6.87E-11 T 06-07-2017 IPR029016 GAF domain-like BWK49_RS10900 a2e91a985be9c93780cace890fce7509 296 SUPERFAMILY SSF55781 86 188 6.87E-11 T 06-07-2017 IPR029016 GAF domain-like BWK49_RS10900 a2e91a985be9c93780cace890fce7509 296 Pfam PF09339 IclR helix-turn-helix domain 14 64 1.2E-6 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 BWK49_RS10900 a2e91a985be9c93780cace890fce7509 296 Gene3D G3DSA:1.10.10.10 8 79 2.3E-9 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS10900 a2e91a985be9c93780cace890fce7509 296 SMART SM00346 6 98 4.2E-6 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 BWK49_RS10900 a2e91a985be9c93780cace890fce7509 296 SUPERFAMILY SSF46785 14 79 2.03E-7 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS10415 1fa53dbc0ed82c487c18ff2168ed7eee 312 Gene3D G3DSA:3.40.50.1820 7 280 1.6E-37 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS10415 1fa53dbc0ed82c487c18ff2168ed7eee 312 PRINTS PR00111 Alpha/beta hydrolase fold signature 112 125 8.1E-6 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS10415 1fa53dbc0ed82c487c18ff2168ed7eee 312 PRINTS PR00111 Alpha/beta hydrolase fold signature 54 69 8.1E-6 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS10415 1fa53dbc0ed82c487c18ff2168ed7eee 312 PRINTS PR00111 Alpha/beta hydrolase fold signature 98 111 8.1E-6 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS10415 1fa53dbc0ed82c487c18ff2168ed7eee 312 SUPERFAMILY SSF53474 7 279 2.84E-39 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS10415 1fa53dbc0ed82c487c18ff2168ed7eee 312 Pfam PF12697 Alpha/beta hydrolase family 31 276 1.3E-15 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS28845 a8a06b27bf6ecdc1f04da7db8d7d973d 613 Pfam PF00823 PPE family 195 319 3.4E-8 T 06-07-2017 IPR000030 PPE family BWK49_RS28845 a8a06b27bf6ecdc1f04da7db8d7d973d 613 Pfam PF00934 PE family 55 131 1.2E-5 T 06-07-2017 IPR000084 PE-PGRS family, N-terminal BWK49_RS28845 a8a06b27bf6ecdc1f04da7db8d7d973d 613 SUPERFAMILY SSF140459 195 349 2.33E-8 T 06-07-2017 BWK49_RS08090 fbe5dc661e9eb415d2636faa33337ac0 382 Pfam PF17198 Protein of unknown function (DUF5135) 97 329 9.1E-81 T 06-07-2017 IPR033459 Protein of unknown function DUF5135 BWK49_RS12935 650d36b6da000ea3b479c5cc0083b75d 379 Gene3D G3DSA:3.40.50.2000 168 358 1.6E-39 T 06-07-2017 BWK49_RS12935 650d36b6da000ea3b479c5cc0083b75d 379 Pfam PF13439 Glycosyltransferase Family 4 16 177 1.7E-13 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 BWK49_RS12935 650d36b6da000ea3b479c5cc0083b75d 379 SUPERFAMILY SSF53756 4 377 4.32E-79 T 06-07-2017 BWK49_RS12935 650d36b6da000ea3b479c5cc0083b75d 379 Pfam PF00534 Glycosyl transferases group 1 192 360 7.2E-44 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 BWK49_RS22865 d9101a9f72dc39f3b3d619110c29f1c0 427 Pfam PF00487 Fatty acid desaturase 69 339 8.3E-37 T 06-07-2017 IPR005804 Fatty acid desaturase domain GO:0006629 BWK49_RS04470 95b06e375001d13f21655081e00322fb 328 Pfam PF12642 Conjugative transposon protein TcpC 125 303 1.6E-9 T 06-07-2017 IPR024735 Conjugative transposon protein TcpC BWK49_RS00555 c29a8ebce99975f387f62563482de947 251 SUPERFAMILY SSF53474 1 245 2.34E-37 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS00555 c29a8ebce99975f387f62563482de947 251 PRINTS PR00111 Alpha/beta hydrolase fold signature 24 39 6.7E-6 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS00555 c29a8ebce99975f387f62563482de947 251 PRINTS PR00111 Alpha/beta hydrolase fold signature 82 95 6.7E-6 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS00555 c29a8ebce99975f387f62563482de947 251 PRINTS PR00111 Alpha/beta hydrolase fold signature 68 81 6.7E-6 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS00555 c29a8ebce99975f387f62563482de947 251 Pfam PF12697 Alpha/beta hydrolase family 1 238 3.0E-21 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS00555 c29a8ebce99975f387f62563482de947 251 Gene3D G3DSA:3.40.50.1820 1 246 4.4E-42 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS03660 eeb9fd2e0fdb0c79479ca174e1d999b3 311 Pfam PF00378 Enoyl-CoA hydratase/isomerase 29 87 5.1E-11 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 BWK49_RS03660 eeb9fd2e0fdb0c79479ca174e1d999b3 311 Pfam PF00378 Enoyl-CoA hydratase/isomerase 102 261 8.7E-27 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 BWK49_RS03660 eeb9fd2e0fdb0c79479ca174e1d999b3 311 Gene3D G3DSA:3.90.226.10 13 271 9.4E-58 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS03660 eeb9fd2e0fdb0c79479ca174e1d999b3 311 SUPERFAMILY SSF52096 22 291 1.37E-56 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS23395 24681388698e8abb0ec271d9195d3d84 339 SUPERFAMILY SSF51182 55 331 2.08E-55 T 06-07-2017 IPR011051 RmlC-like cupin domain BWK49_RS23395 24681388698e8abb0ec271d9195d3d84 339 Gene3D G3DSA:2.60.120.10 207 324 6.0E-12 T 06-07-2017 IPR014710 RmlC-like jelly roll fold BWK49_RS23395 24681388698e8abb0ec271d9195d3d84 339 Gene3D G3DSA:2.60.120.10 87 178 5.7E-12 T 06-07-2017 IPR014710 RmlC-like jelly roll fold BWK49_RS05685 daee50d22480425154ca7d4ac6f9c21d 342 Pfam PF01381 Helix-turn-helix 15 64 6.0E-12 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 BWK49_RS05685 daee50d22480425154ca7d4ac6f9c21d 342 SMART SM00530 10 65 5.9E-13 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 BWK49_RS05685 daee50d22480425154ca7d4ac6f9c21d 342 SUPERFAMILY SSF47413 10 75 3.49E-13 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 BWK49_RS05685 daee50d22480425154ca7d4ac6f9c21d 342 Pfam PF06114 Domain of unknown function (DUF955) 157 271 2.5E-16 T 06-07-2017 IPR010359 HTH domain, IrrE-type BWK49_RS05685 daee50d22480425154ca7d4ac6f9c21d 342 Gene3D G3DSA:1.10.260.40 10 65 8.1E-13 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 BWK49_RS12250 1a52cd921b82f3cfebc5996946001a6c 217 SUPERFAMILY SSF69118 6 215 1.26E-33 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 BWK49_RS12250 1a52cd921b82f3cfebc5996946001a6c 217 Pfam PF02627 Carboxymuconolactone decarboxylase family 42 96 4.8E-6 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 BWK49_RS12250 1a52cd921b82f3cfebc5996946001a6c 217 Pfam PF02627 Carboxymuconolactone decarboxylase family 140 212 4.2E-8 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 BWK49_RS12250 1a52cd921b82f3cfebc5996946001a6c 217 Gene3D G3DSA:1.20.1290.10 8 105 7.9E-9 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 BWK49_RS12250 1a52cd921b82f3cfebc5996946001a6c 217 Gene3D G3DSA:1.20.1290.10 126 215 7.5E-10 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 BWK49_RS03950 f06e3692646c728210e77e4fb45789b1 360 Pfam PF01370 NAD dependent epimerase/dehydratase family 5 175 7.4E-26 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 BWK49_RS03950 f06e3692646c728210e77e4fb45789b1 360 SUPERFAMILY SSF51735 1 301 3.84E-51 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS03950 f06e3692646c728210e77e4fb45789b1 360 Gene3D G3DSA:3.40.50.720 3 195 9.4E-43 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS26235 e516fa4edc1d677d5ab6516085af0726 190 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 3 181 2.3E-64 T 06-07-2017 IPR011962 Deoxycytidine triphosphate deaminase GO:0006229|GO:0008829 KEGG: 00240+3.5.4.13|MetaCyc: PWY-7187 BWK49_RS26235 e516fa4edc1d677d5ab6516085af0726 190 SUPERFAMILY SSF51283 2 184 1.18E-55 T 06-07-2017 IPR029054 dUTPase-like BWK49_RS26235 e516fa4edc1d677d5ab6516085af0726 190 Hamap MF_00146 Deoxycytidine triphosphate deaminase [dcd]. 1 182 34.754 T 06-07-2017 IPR011962 Deoxycytidine triphosphate deaminase GO:0006229|GO:0008829 KEGG: 00240+3.5.4.13|MetaCyc: PWY-7187 BWK49_RS26235 e516fa4edc1d677d5ab6516085af0726 190 Pfam PF00692 dUTPase 70 178 1.1E-10 T 06-07-2017 IPR008180 Deoxyuridine triphosphate nucleotidohydrolase/Deoxycytidine triphosphate deaminase GO:0016787|GO:0046080 BWK49_RS26235 e516fa4edc1d677d5ab6516085af0726 190 Gene3D G3DSA:2.70.40.10 2 184 2.6E-65 T 06-07-2017 IPR029054 dUTPase-like BWK49_RS23065 10463f5b2f0cf953a75445b94d228794 216 Gene3D G3DSA:1.20.1510.10 27 206 2.0E-10 T 06-07-2017 IPR027469 Cation efflux protein transmembrane domain BWK49_RS23065 10463f5b2f0cf953a75445b94d228794 216 SUPERFAMILY SSF161111 26 210 5.75E-21 T 06-07-2017 BWK49_RS23065 10463f5b2f0cf953a75445b94d228794 216 Pfam PF01545 Cation efflux family 94 205 2.3E-7 T 06-07-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 BWK49_RS12640 881361b42e0250f51520479ee6ad900d 286 SUPERFAMILY SSF51679 7 256 3.83E-53 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS12640 881361b42e0250f51520479ee6ad900d 286 TIGRFAM TIGR03619 F420_Rv2161c: probable F420-dependent oxidoreductase, Rv2161c family 17 243 7.2E-56 T 06-07-2017 IPR019921 Luciferase-like, F420-dependent oxidoreductase, Rv2161c, predicted BWK49_RS12640 881361b42e0250f51520479ee6ad900d 286 Pfam PF00296 Luciferase-like monooxygenase 11 246 4.2E-46 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS12640 881361b42e0250f51520479ee6ad900d 286 Gene3D G3DSA:3.20.20.30 12 268 6.9E-60 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS10210 95af97c7a93946005bff0ce963965dc8 252 Pfam PF14032 PknH-like extracellular domain 40 247 4.2E-37 T 06-07-2017 IPR026954 PknH-like extracellular domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 BWK49_RS26060 b67968d12ea87f60483a5c1ce57462da 215 SUPERFAMILY SSF75217 50 209 2.09E-36 T 06-07-2017 IPR029028 Alpha/beta knot methyltransferases BWK49_RS26060 b67968d12ea87f60483a5c1ce57462da 215 Gene3D G3DSA:3.40.1280.10 47 209 5.4E-38 T 06-07-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal BWK49_RS26060 b67968d12ea87f60483a5c1ce57462da 215 Pfam PF00588 SpoU rRNA Methylase family 66 202 7.0E-24 T 06-07-2017 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 BWK49_RS26940 4247c2fa2dc7c4a81f9a5d354315c2c8 492 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 254 261 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 BWK49_RS26940 4247c2fa2dc7c4a81f9a5d354315c2c8 492 SUPERFAMILY SSF53720 7 486 6.15E-156 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 BWK49_RS26940 4247c2fa2dc7c4a81f9a5d354315c2c8 492 Gene3D G3DSA:3.40.605.10 10 268 2.4E-87 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 BWK49_RS26940 4247c2fa2dc7c4a81f9a5d354315c2c8 492 Pfam PF00171 Aldehyde dehydrogenase family 17 482 6.5E-163 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 BWK49_RS26940 4247c2fa2dc7c4a81f9a5d354315c2c8 492 Gene3D G3DSA:3.40.309.10 269 457 7.4E-64 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 BWK49_RS28980 da308371fe5230c5ff6ef4283fcefbd9 384 SUPERFAMILY SSF140459 5 171 2.62E-51 T 06-07-2017 BWK49_RS28980 da308371fe5230c5ff6ef4283fcefbd9 384 Pfam PF00823 PPE family 5 158 4.6E-54 T 06-07-2017 IPR000030 PPE family BWK49_RS28980 da308371fe5230c5ff6ef4283fcefbd9 384 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 295 383 2.4E-8 T 06-07-2017 IPR022171 PPE family, C-terminal BWK49_RS09600 2f04db278fe7e99aaf2d0557c60238a6 240 Pfam PF08924 Domain of unknown function (DUF1906) 51 176 6.2E-29 T 06-07-2017 IPR015020 Protein of unknown function DUF1906 BWK49_RS09600 2f04db278fe7e99aaf2d0557c60238a6 240 Gene3D G3DSA:3.20.20.80 63 182 5.6E-10 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 BWK49_RS09600 2f04db278fe7e99aaf2d0557c60238a6 240 SUPERFAMILY SSF51445 58 199 1.47E-6 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily BWK49_RS25440 1cabb8a0715882250aceb102c12806d6 205 ProDom PD082580 HEPARIN-BINDING HEMAGGLUTININ ADHESIN GLYCOPROTEIN DIRECT VIRULENCE SEQUENCING CELL ADHESION HOMOLOG 1 159 1.0E-51 T 06-07-2017 IPR020340 Heparin-binding haemagglutinin, bacteria GO:0007155|GO:0008201|GO:0009405|GO:0009986 BWK49_RS02370 2213b604fc4b4d554908c48d74ca435f 418 SMART SM00507 297 348 2.5E-10 T 06-07-2017 IPR003615 HNH nuclease BWK49_RS02370 2213b604fc4b4d554908c48d74ca435f 418 Pfam PF01844 HNH endonuclease 314 352 1.8E-5 T 06-07-2017 IPR002711 HNH endonuclease GO:0003676|GO:0004519 BWK49_RS02370 2213b604fc4b4d554908c48d74ca435f 418 Pfam PF02720 Domain of unknown function (DUF222) 22 306 1.2E-63 T 06-07-2017 IPR003870 Domain of unknown function DUF222 BWK49_RS22730 39b133ee096009660a3df7aba179d82f 160 Gene3D G3DSA:3.40.630.30 1 157 6.1E-52 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase BWK49_RS22730 39b133ee096009660a3df7aba179d82f 160 SUPERFAMILY SSF55729 5 150 8.75E-32 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase BWK49_RS22730 39b133ee096009660a3df7aba179d82f 160 Pfam PF00583 Acetyltransferase (GNAT) family 56 133 2.3E-13 T 06-07-2017 IPR000182 GNAT domain GO:0008080 BWK49_RS14375 7e1c23a8ddc5a5eeeaf7596cd2a8fb1d 258 Pfam PF01083 Cutinase 73 258 1.0E-48 T 06-07-2017 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 BWK49_RS14375 7e1c23a8ddc5a5eeeaf7596cd2a8fb1d 258 SUPERFAMILY SSF53474 74 257 3.8E-32 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS14375 7e1c23a8ddc5a5eeeaf7596cd2a8fb1d 258 ProSitePatterns PS00155 Cutinase, serine active site. 142 154 - T 06-07-2017 IPR011150 Cutinase, monofunctional GO:0005576|GO:0050525 BWK49_RS14375 7e1c23a8ddc5a5eeeaf7596cd2a8fb1d 258 SMART SM01110 72 258 2.7E-88 T 06-07-2017 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 BWK49_RS14375 7e1c23a8ddc5a5eeeaf7596cd2a8fb1d 258 Gene3D G3DSA:3.40.50.1820 73 258 5.9E-47 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS01730 519da691697111acbc42eba77bce23af 59 SUPERFAMILY SSF51569 17 58 9.84E-7 T 06-07-2017 BWK49_RS01730 519da691697111acbc42eba77bce23af 59 Gene3D G3DSA:3.20.20.70 16 58 2.4E-8 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 BWK49_RS03615 b2df2d6b49a0b2588db274b8d2ab5abd 354 Pfam PF02470 MlaD protein 41 115 1.2E-14 T 06-07-2017 IPR003399 Mce/MlaD BWK49_RS03615 b2df2d6b49a0b2588db274b8d2ab5abd 354 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 14 293 2.0E-80 T 06-07-2017 IPR005693 Virulence factor Mce protein BWK49_RS03615 b2df2d6b49a0b2588db274b8d2ab5abd 354 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 177 195 1.6E-14 T 06-07-2017 IPR005693 Virulence factor Mce protein BWK49_RS03615 b2df2d6b49a0b2588db274b8d2ab5abd 354 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 297 316 1.6E-14 T 06-07-2017 IPR005693 Virulence factor Mce protein BWK49_RS03615 b2df2d6b49a0b2588db274b8d2ab5abd 354 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 93 109 1.6E-14 T 06-07-2017 IPR005693 Virulence factor Mce protein BWK49_RS03615 b2df2d6b49a0b2588db274b8d2ab5abd 354 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 246 265 1.6E-14 T 06-07-2017 IPR005693 Virulence factor Mce protein BWK49_RS09880 f7e83209dfb647cb1e50f049006b96da 162 TIGRFAM TIGR02133 RPI_actino: ribose 5-phosphate isomerase 4 151 1.2E-65 T 06-07-2017 IPR011860 Ribose 5-phosphate isomerase GO:0004751 BWK49_RS09880 f7e83209dfb647cb1e50f049006b96da 162 Pfam PF02502 Ribose/Galactose Isomerase 6 143 1.1E-43 T 06-07-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 BWK49_RS09880 f7e83209dfb647cb1e50f049006b96da 162 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 6 150 2.7E-57 T 06-07-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 BWK49_RS09880 f7e83209dfb647cb1e50f049006b96da 162 SUPERFAMILY SSF89623 4 155 7.46E-52 T 06-07-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 BWK49_RS09880 f7e83209dfb647cb1e50f049006b96da 162 PIRSF PIRSF005384 4 152 1.5E-49 T 06-07-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 BWK49_RS09880 f7e83209dfb647cb1e50f049006b96da 162 Gene3D G3DSA:3.40.1400.10 3 153 3.6E-54 T 06-07-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 BWK49_RS12290 a6d9396579f4f6e21e37d98fd939c3a0 86 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 66 8.0E-9 T 06-07-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM BWK49_RS12290 a6d9396579f4f6e21e37d98fd939c3a0 86 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 4 56 7.2E-15 T 06-07-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM BWK49_RS12290 a6d9396579f4f6e21e37d98fd939c3a0 86 Gene3D G3DSA:3.40.1620.10 2 39 1.5E-6 T 06-07-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM BWK49_RS12290 a6d9396579f4f6e21e37d98fd939c3a0 86 SUPERFAMILY SSF143120 1 41 3.66E-7 T 06-07-2017 BWK49_RS14155 32077ba5bba1623a98151bcdb127387a 780 SUPERFAMILY SSF89550 313 544 1.45E-7 T 06-07-2017 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 BWK49_RS05970 49b0cf27b279977bd11884d17d8c2f03 293 Gene3D G3DSA:3.40.50.2000 35 154 1.2E-5 T 06-07-2017 BWK49_RS05970 49b0cf27b279977bd11884d17d8c2f03 293 Gene3D G3DSA:3.40.50.2000 192 243 1.2E-9 T 06-07-2017 BWK49_RS05970 49b0cf27b279977bd11884d17d8c2f03 293 SUPERFAMILY SSF53756 37 284 6.28E-12 T 06-07-2017 BWK49_RS19860 4bb73655d4cf698dddd21b8297a2a718 227 Gene3D G3DSA:3.90.470.20 123 184 6.2E-5 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 BWK49_RS19860 4bb73655d4cf698dddd21b8297a2a718 227 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 109 188 3.0E-11 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 BWK49_RS19860 4bb73655d4cf698dddd21b8297a2a718 227 SUPERFAMILY SSF56214 108 226 4.53E-14 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 BWK49_RS19860 4bb73655d4cf698dddd21b8297a2a718 227 PRINTS PR01399 Enterobactin synthetase component D signature 45 65 1.3E-27 T 06-07-2017 IPR003542 Enterobactin synthetase-like, component D GO:0009239|GO:0009366|GO:0016780 BWK49_RS19860 4bb73655d4cf698dddd21b8297a2a718 227 PRINTS PR01399 Enterobactin synthetase component D signature 75 93 1.3E-27 T 06-07-2017 IPR003542 Enterobactin synthetase-like, component D GO:0009239|GO:0009366|GO:0016780 BWK49_RS19860 4bb73655d4cf698dddd21b8297a2a718 227 PRINTS PR01399 Enterobactin synthetase component D signature 150 166 1.3E-27 T 06-07-2017 IPR003542 Enterobactin synthetase-like, component D GO:0009239|GO:0009366|GO:0016780 BWK49_RS14575 67a1c8a1516f954deff2b814d6f2d99d 138 Gene3D G3DSA:3.30.530.20 7 135 7.1E-36 T 06-07-2017 IPR023393 START-like domain BWK49_RS14575 67a1c8a1516f954deff2b814d6f2d99d 138 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 17 125 5.0E-19 T 06-07-2017 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 BWK49_RS14575 67a1c8a1516f954deff2b814d6f2d99d 138 SUPERFAMILY SSF55961 8 135 3.67E-33 T 06-07-2017 BWK49_RS11980 d86a71f187e1527cc33241c36fd30051 280 Pfam PF13622 Thioesterase-like superfamily 37 260 9.7E-19 T 06-07-2017 BWK49_RS11980 d86a71f187e1527cc33241c36fd30051 280 SUPERFAMILY SSF54637 43 119 1.62E-6 T 06-07-2017 IPR029069 HotDog domain BWK49_RS11980 d86a71f187e1527cc33241c36fd30051 280 Gene3D G3DSA:3.10.129.10 29 117 9.9E-7 T 06-07-2017 IPR029069 HotDog domain BWK49_RS21110 29cfc722192e1e8b94423c36bce5d4fd 359 SUPERFAMILY SSF51735 3 326 1.47E-44 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS21110 29cfc722192e1e8b94423c36bce5d4fd 359 Gene3D G3DSA:3.90.25.10 225 323 4.6E-9 T 06-07-2017 BWK49_RS21110 29cfc722192e1e8b94423c36bce5d4fd 359 Pfam PF01370 NAD dependent epimerase/dehydratase family 5 163 1.8E-18 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 BWK49_RS21110 29cfc722192e1e8b94423c36bce5d4fd 359 Gene3D G3DSA:3.40.50.720 2 224 4.1E-33 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS26395 44207a24fcd910cec83ca37ee7973121 468 ProSitePatterns PS00523 Sulfatases signature 1. 54 66 - T 06-07-2017 IPR024607 Sulfatase, conserved site BWK49_RS26395 44207a24fcd910cec83ca37ee7973121 468 Pfam PF00884 Sulfatase 10 286 1.2E-44 T 06-07-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 BWK49_RS26395 44207a24fcd910cec83ca37ee7973121 468 SUPERFAMILY SSF53649 8 422 3.49E-90 T 06-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 BWK49_RS26395 44207a24fcd910cec83ca37ee7973121 468 Gene3D G3DSA:3.30.1120.10 330 424 2.6E-15 T 06-07-2017 BWK49_RS26395 44207a24fcd910cec83ca37ee7973121 468 Gene3D G3DSA:3.40.720.10 8 126 5.2E-31 T 06-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 BWK49_RS26395 44207a24fcd910cec83ca37ee7973121 468 Gene3D G3DSA:3.40.720.10 130 329 2.5E-35 T 06-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 BWK49_RS24860 dda89ba0892ca3aeb4911190dc952494 149 ProSitePatterns PS00934 Glyoxalase I signature 1. 10 31 - T 06-07-2017 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 BWK49_RS24860 dda89ba0892ca3aeb4911190dc952494 149 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 136 2.2E-14 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain BWK49_RS24860 dda89ba0892ca3aeb4911190dc952494 149 SUPERFAMILY SSF54593 8 138 1.88E-26 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS24860 dda89ba0892ca3aeb4911190dc952494 149 Gene3D G3DSA:3.10.180.10 8 138 3.4E-27 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS10610 d969a27c96467c55cd41ab43240534a7 442 Gene3D G3DSA:1.20.1250.20 211 409 5.1E-10 T 06-07-2017 BWK49_RS10610 d969a27c96467c55cd41ab43240534a7 442 Gene3D G3DSA:1.20.1250.20 13 194 1.3E-24 T 06-07-2017 BWK49_RS10610 d969a27c96467c55cd41ab43240534a7 442 SUPERFAMILY SSF103473 13 410 2.75E-44 T 06-07-2017 IPR020846 Major facilitator superfamily domain BWK49_RS10610 d969a27c96467c55cd41ab43240534a7 442 Pfam PF07690 Major Facilitator Superfamily 19 364 9.6E-26 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 BWK49_RS00295 ec8490ef783997aed3e2aba736d17533 261 TIGRFAM TIGR03856 F420_MSMEG_2906: probable F420-dependent oxidoreductase, MSMEG_2906 family 7 259 3.0E-136 T 06-07-2017 IPR022480 F420-dependent oxidoreductase, MSMEG2906 BWK49_RS00295 ec8490ef783997aed3e2aba736d17533 261 Pfam PF00296 Luciferase-like monooxygenase 9 215 6.5E-33 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS00295 ec8490ef783997aed3e2aba736d17533 261 SUPERFAMILY SSF51679 7 216 7.36E-45 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS00295 ec8490ef783997aed3e2aba736d17533 261 Gene3D G3DSA:3.20.20.30 6 216 3.2E-50 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS21515 2c91bb35ecefeb5cc8d2661e7ce8c53e 942 SUPERFAMILY SSF82866 722 931 2.88E-32 T 06-07-2017 BWK49_RS21515 2c91bb35ecefeb5cc8d2661e7ce8c53e 942 Pfam PF03176 MMPL family 57 384 1.8E-96 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 BWK49_RS21515 2c91bb35ecefeb5cc8d2661e7ce8c53e 942 Pfam PF03176 MMPL family 614 940 2.2E-82 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 BWK49_RS21515 2c91bb35ecefeb5cc8d2661e7ce8c53e 942 SUPERFAMILY SSF82866 154 351 4.58E-27 T 06-07-2017 BWK49_RS21515 2c91bb35ecefeb5cc8d2661e7ce8c53e 942 Gene3D G3DSA:1.20.1640.10 730 931 5.8E-25 T 06-07-2017 BWK49_RS21515 2c91bb35ecefeb5cc8d2661e7ce8c53e 942 Gene3D G3DSA:1.20.1640.10 153 352 4.5E-27 T 06-07-2017 BWK49_RS21515 2c91bb35ecefeb5cc8d2661e7ce8c53e 942 TIGRFAM TIGR00833 actII: transport protein 23 931 1.5E-265 T 06-07-2017 IPR004707 Membrane transport protein MmpL family GO:0016021 BWK49_RS10220 2d2b42b54583b053ac5ed6be57015dd5 682 Pfam PF00723 Glycosyl hydrolases family 15 295 607 3.5E-50 T 06-07-2017 IPR011613 Glycoside hydrolase family 15/Phosphorylase b kinase regulatory chain family Reactome: R-HSA-70221 BWK49_RS10220 2d2b42b54583b053ac5ed6be57015dd5 682 Gene3D G3DSA:1.50.10.10 291 668 2.0E-91 T 06-07-2017 IPR012341 Six-hairpin glycosidase GO:0003824 BWK49_RS10220 2d2b42b54583b053ac5ed6be57015dd5 682 SUPERFAMILY SSF48208 264 662 1.11E-98 T 06-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 BWK49_RS24160 e68ba08fd2671690a52f13103a30fc87 453 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 230 401 5.8E-23 T 06-07-2017 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 BWK49_RS24160 e68ba08fd2671690a52f13103a30fc87 453 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 7 103 5.6E-11 T 06-07-2017 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 BWK49_RS24160 e68ba08fd2671690a52f13103a30fc87 453 SUPERFAMILY SSF53067 221 443 8.83E-46 T 06-07-2017 BWK49_RS24160 e68ba08fd2671690a52f13103a30fc87 453 SUPERFAMILY SSF53067 6 216 7.86E-25 T 06-07-2017 BWK49_RS24160 e68ba08fd2671690a52f13103a30fc87 453 Gene3D G3DSA:3.30.420.40 4 104 8.4E-16 T 06-07-2017 BWK49_RS24160 e68ba08fd2671690a52f13103a30fc87 453 Gene3D G3DSA:3.30.420.40 224 443 3.2E-37 T 06-07-2017 BWK49_RS13095 0c7a055702f67fb83d459213b1ca09c9 493 SUPERFAMILY SSF53244 331 479 3.66E-42 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 BWK49_RS13095 0c7a055702f67fb83d459213b1ca09c9 493 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 13 476 3.2E-153 T 06-07-2017 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 BWK49_RS13095 0c7a055702f67fb83d459213b1ca09c9 493 SUPERFAMILY SSF51984 11 102 1.96E-20 T 06-07-2017 BWK49_RS13095 0c7a055702f67fb83d459213b1ca09c9 493 Pfam PF01225 Mur ligase family, catalytic domain 13 115 1.0E-23 T 06-07-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 BWK49_RS13095 0c7a055702f67fb83d459213b1ca09c9 493 Pfam PF08245 Mur ligase middle domain 120 312 5.2E-24 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 BWK49_RS13095 0c7a055702f67fb83d459213b1ca09c9 493 Gene3D G3DSA:3.40.1190.10 104 333 3.3E-74 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 BWK49_RS13095 0c7a055702f67fb83d459213b1ca09c9 493 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 10 482 38.338 T 06-07-2017 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 BWK49_RS13095 0c7a055702f67fb83d459213b1ca09c9 493 Pfam PF02875 Mur ligase family, glutamate ligase domain 332 423 3.9E-22 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 BWK49_RS13095 0c7a055702f67fb83d459213b1ca09c9 493 Gene3D G3DSA:3.40.50.720 12 102 1.1E-28 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS13095 0c7a055702f67fb83d459213b1ca09c9 493 Gene3D G3DSA:3.90.190.20 334 480 1.7E-48 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 BWK49_RS13095 0c7a055702f67fb83d459213b1ca09c9 493 SUPERFAMILY SSF53623 102 330 6.93E-54 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 BWK49_RS13790 175adc919011e11037911a31aed2ef6e 95 Pfam PF11829 Protein of unknown function (DUF3349) 6 87 2.1E-22 T 06-07-2017 IPR021784 Protein of unknown function DUF3349 BWK49_RS20905 4770f69414e3fbddf6acedbd8554b6c6 458 SUPERFAMILY SSF103473 23 414 1.83E-58 T 06-07-2017 IPR020846 Major facilitator superfamily domain BWK49_RS20905 4770f69414e3fbddf6acedbd8554b6c6 458 Gene3D G3DSA:1.20.1250.20 236 410 1.5E-17 T 06-07-2017 BWK49_RS20905 4770f69414e3fbddf6acedbd8554b6c6 458 Gene3D G3DSA:1.20.1250.20 36 220 4.0E-28 T 06-07-2017 BWK49_RS20905 4770f69414e3fbddf6acedbd8554b6c6 458 Pfam PF07690 Major Facilitator Superfamily 44 380 5.8E-41 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 BWK49_RS04155 5c01690338bb42e18352e71a1cc8585f 706 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 273 446 7.4E-46 T 06-07-2017 IPR004474 Cell envelope-related transcriptional attenuator domain BWK49_RS04155 5c01690338bb42e18352e71a1cc8585f 706 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 580 663 1.5E-14 T 06-07-2017 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain BWK49_RS04155 5c01690338bb42e18352e71a1cc8585f 706 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 272 447 1.2E-60 T 06-07-2017 IPR004474 Cell envelope-related transcriptional attenuator domain BWK49_RS12950 baeb140018dba42206132922b25323de 145 Gene3D G3DSA:3.30.530.20 4 144 3.2E-22 T 06-07-2017 IPR023393 START-like domain BWK49_RS12950 baeb140018dba42206132922b25323de 145 SUPERFAMILY SSF55961 4 144 2.22E-31 T 06-07-2017 BWK49_RS12950 baeb140018dba42206132922b25323de 145 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 4 143 7.5E-16 T 06-07-2017 IPR019587 Polyketide cyclase/dehydrase BWK49_RS09445 0c4a8776debeb388212642712def6736 225 SUPERFAMILY SSF52540 13 199 6.47E-9 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS09445 0c4a8776debeb388212642712def6736 225 Gene3D G3DSA:3.40.50.300 12 200 2.2E-8 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS22430 321d0f292f1b1cc27e51bb72351ce17d 257 Pfam PF11738 Protein of unknown function (DUF3298) 161 250 1.9E-10 T 06-07-2017 IPR021729 Domain of unknown function DUF3298 BWK49_RS22430 321d0f292f1b1cc27e51bb72351ce17d 257 Gene3D G3DSA:3.90.640.20 215 256 2.2E-7 T 06-07-2017 IPR021729 Domain of unknown function DUF3298 BWK49_RS09420 94d40ef0820d9b3b3c133ec7274fb000 347 Pfam PF00296 Luciferase-like monooxygenase 20 323 2.1E-38 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS09420 94d40ef0820d9b3b3c133ec7274fb000 347 TIGRFAM TIGR03857 F420_MSMEG_2249: probable F420-dependent oxidoreductase, MSMEG_2249 family 9 336 1.8E-148 T 06-07-2017 IPR022378 F420-dependent oxidoreductase-predicted, MSMEG2249 BWK49_RS09420 94d40ef0820d9b3b3c133ec7274fb000 347 SUPERFAMILY SSF51679 9 338 2.62E-50 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS09420 94d40ef0820d9b3b3c133ec7274fb000 347 Gene3D G3DSA:3.20.20.30 9 337 8.2E-55 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS11205 89f18947789fc409d6a30826a4215529 326 SUPERFAMILY SSF55469 230 323 9.85E-8 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 BWK49_RS11205 89f18947789fc409d6a30826a4215529 326 Gene3D G3DSA:3.40.109.10 3 89 1.1E-25 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 BWK49_RS11205 89f18947789fc409d6a30826a4215529 326 Gene3D G3DSA:3.40.109.10 211 323 1.1E-25 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 BWK49_RS11205 89f18947789fc409d6a30826a4215529 326 Pfam PF00881 Nitroreductase family 228 301 6.1E-5 T 06-07-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 BWK49_RS11205 89f18947789fc409d6a30826a4215529 326 SUPERFAMILY SSF55469 3 80 1.71E-10 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 BWK49_RS24150 2434400905b0c48b07dd7ddcc321180a 307 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 17 283 1.3E-78 T 06-07-2017 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 BWK49_RS24150 2434400905b0c48b07dd7ddcc321180a 307 Pfam PF04072 Leucine carboxyl methyltransferase 19 206 4.4E-63 T 06-07-2017 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 BWK49_RS24150 2434400905b0c48b07dd7ddcc321180a 307 SUPERFAMILY SSF53335 15 289 4.32E-79 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS24150 2434400905b0c48b07dd7ddcc321180a 307 Gene3D G3DSA:3.40.50.150 14 220 1.3E-15 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS16055 d19c9f2d2f8c1ff42fad04127cc65aba 96 ProDom PD020015 MB2016C IRON REGULATED MB3297 RV1993C/MT2049 RV0968/MT0996 IRP10 ML0748 MB0993 1 94 5.0E-16 T 06-07-2017 IPR009963 Protein of unknown function DUF1490 BWK49_RS16055 d19c9f2d2f8c1ff42fad04127cc65aba 96 Pfam PF07371 Protein of unknown function (DUF1490) 1 91 2.1E-36 T 06-07-2017 IPR009963 Protein of unknown function DUF1490 BWK49_RS04050 4c317f9ec3e3197bd26ad9115292201f 404 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 151 404 3.4E-96 T 06-07-2017 IPR024516 Mammalian cell entry, C-terminal BWK49_RS04050 4c317f9ec3e3197bd26ad9115292201f 404 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 14 303 3.8E-75 T 06-07-2017 IPR005693 Virulence factor Mce protein BWK49_RS04050 4c317f9ec3e3197bd26ad9115292201f 404 Pfam PF02470 MlaD protein 42 122 1.5E-13 T 06-07-2017 IPR003399 Mce/MlaD BWK49_RS24870 319277c494526aa19bac8c431ae1c419 604 Gene3D G3DSA:3.50.50.60 482 571 8.0E-52 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS24870 319277c494526aa19bac8c431ae1c419 604 Gene3D G3DSA:3.50.50.60 63 249 8.0E-52 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS24870 319277c494526aa19bac8c431ae1c419 604 SUPERFAMILY SSF51905 205 439 2.98E-39 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS24870 319277c494526aa19bac8c431ae1c419 604 Pfam PF13450 NAD(P)-binding Rossmann-like domain 71 121 4.9E-9 T 06-07-2017 BWK49_RS24870 319277c494526aa19bac8c431ae1c419 604 Gene3D G3DSA:3.50.50.60 250 283 3.1E-4 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS24870 319277c494526aa19bac8c431ae1c419 604 SUPERFAMILY SSF51905 65 285 4.81E-42 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS10630 170a29e4daee76a90713773da7569688 98 SUPERFAMILY SSF140453 4 97 1.57E-19 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like BWK49_RS10630 170a29e4daee76a90713773da7569688 98 Gene3D G3DSA:1.10.287.1060 1 97 1.0E-11 T 06-07-2017 BWK49_RS10630 170a29e4daee76a90713773da7569688 98 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 5 93 1.6E-19 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like BWK49_RS10630 170a29e4daee76a90713773da7569688 98 Pfam PF06013 Proteins of 100 residues with WXG 5 90 2.4E-19 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like BWK49_RS07155 c3626da4834a332c49884c1e7322c6f6 309 TIGRFAM TIGR03619 F420_Rv2161c: probable F420-dependent oxidoreductase, Rv2161c family 23 271 2.6E-57 T 06-07-2017 IPR019921 Luciferase-like, F420-dependent oxidoreductase, Rv2161c, predicted BWK49_RS07155 c3626da4834a332c49884c1e7322c6f6 309 Pfam PF00296 Luciferase-like monooxygenase 20 260 4.8E-42 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS07155 c3626da4834a332c49884c1e7322c6f6 309 Gene3D G3DSA:3.20.20.30 1 289 1.0E-56 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS07155 c3626da4834a332c49884c1e7322c6f6 309 SUPERFAMILY SSF51679 1 290 1.57E-55 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS09430 f8493cde008d59da87f5a221ca188e42 407 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 348 357 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 BWK49_RS09430 f8493cde008d59da87f5a221ca188e42 407 SUPERFAMILY SSF48264 17 406 2.36E-89 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS09430 f8493cde008d59da87f5a221ca188e42 407 PRINTS PR00385 P450 superfamily signature 355 366 2.8E-6 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS09430 f8493cde008d59da87f5a221ca188e42 407 PRINTS PR00385 P450 superfamily signature 346 355 2.8E-6 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS09430 f8493cde008d59da87f5a221ca188e42 407 PRINTS PR00385 P450 superfamily signature 245 262 2.8E-6 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS09430 f8493cde008d59da87f5a221ca188e42 407 Gene3D G3DSA:1.10.630.10 14 404 6.2E-111 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS09430 f8493cde008d59da87f5a221ca188e42 407 PRINTS PR00359 B-class P450 signature 297 324 2.3E-44 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS09430 f8493cde008d59da87f5a221ca188e42 407 PRINTS PR00359 B-class P450 signature 355 366 2.3E-44 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS09430 f8493cde008d59da87f5a221ca188e42 407 PRINTS PR00359 B-class P450 signature 346 355 2.3E-44 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS09430 f8493cde008d59da87f5a221ca188e42 407 PRINTS PR00359 B-class P450 signature 91 102 2.3E-44 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS09430 f8493cde008d59da87f5a221ca188e42 407 PRINTS PR00359 B-class P450 signature 138 154 2.3E-44 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS09430 f8493cde008d59da87f5a221ca188e42 407 PRINTS PR00359 B-class P450 signature 280 291 2.3E-44 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS09430 f8493cde008d59da87f5a221ca188e42 407 PRINTS PR00359 B-class P450 signature 325 340 2.3E-44 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS09430 f8493cde008d59da87f5a221ca188e42 407 PRINTS PR00359 B-class P450 signature 199 221 2.3E-44 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS09430 f8493cde008d59da87f5a221ca188e42 407 PRINTS PR00359 B-class P450 signature 155 170 2.3E-44 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS09430 f8493cde008d59da87f5a221ca188e42 407 Pfam PF00067 Cytochrome P450 158 379 1.2E-25 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS00205 7400b49452c864729f73865084a33f29 272 Gene3D G3DSA:3.90.1720.10 160 263 4.7E-36 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain BWK49_RS00205 7400b49452c864729f73865084a33f29 272 Pfam PF00877 NlpC/P60 family 176 262 4.6E-20 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain BWK49_RS00205 7400b49452c864729f73865084a33f29 272 SUPERFAMILY SSF54001 159 264 9.32E-33 T 06-07-2017 BWK49_RS12845 047b0d09b355b08e72008c6d56dd233c 358 SUPERFAMILY SSF110738 1 346 4.18E-85 T 06-07-2017 IPR004381 Glycerate kinase GO:0008887|GO:0031388 BWK49_RS12845 047b0d09b355b08e72008c6d56dd233c 358 Pfam PF02595 Glycerate kinase family 155 347 2.7E-52 T 06-07-2017 IPR004381 Glycerate kinase GO:0008887|GO:0031388 BWK49_RS12845 047b0d09b355b08e72008c6d56dd233c 358 Pfam PF02595 Glycerate kinase family 3 151 2.9E-42 T 06-07-2017 IPR004381 Glycerate kinase GO:0008887|GO:0031388 BWK49_RS12845 047b0d09b355b08e72008c6d56dd233c 358 Gene3D G3DSA:3.90.1510.10 154 251 1.1E-26 T 06-07-2017 IPR018193 Glycerate kinase, flavodoxin-like domain GO:0008887|GO:0031388 BWK49_RS12845 047b0d09b355b08e72008c6d56dd233c 358 Gene3D G3DSA:3.90.1510.10 42 151 4.0E-33 T 06-07-2017 IPR018193 Glycerate kinase, flavodoxin-like domain GO:0008887|GO:0031388 BWK49_RS22165 40adb897759d05839302a6a924971b91 260 Gene3D G3DSA:3.40.50.10320 43 235 1.5E-42 T 06-07-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 BWK49_RS22165 40adb897759d05839302a6a924971b91 260 SUPERFAMILY SSF102588 44 252 1.96E-43 T 06-07-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 BWK49_RS22165 40adb897759d05839302a6a924971b91 260 Pfam PF02585 GlcNAc-PI de-N-acetylase 48 173 3.8E-25 T 06-07-2017 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 BWK49_RS11355 906114e68b166ac9ec2a79ecb7c41e3e 545 SUPERFAMILY SSF56801 25 539 2.75E-130 T 06-07-2017 BWK49_RS11355 906114e68b166ac9ec2a79ecb7c41e3e 545 Gene3D G3DSA:3.40.50.980 36 204 2.9E-30 T 06-07-2017 BWK49_RS11355 906114e68b166ac9ec2a79ecb7c41e3e 545 Pfam PF13193 AMP-binding enzyme C-terminal domain 458 532 5.9E-7 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain BWK49_RS11355 906114e68b166ac9ec2a79ecb7c41e3e 545 Pfam PF00501 AMP-binding enzyme 42 447 5.1E-80 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 BWK49_RS11355 906114e68b166ac9ec2a79ecb7c41e3e 545 Gene3D G3DSA:3.40.50.980 205 356 5.4E-31 T 06-07-2017 BWK49_RS11355 906114e68b166ac9ec2a79ecb7c41e3e 545 Gene3D G3DSA:2.30.38.10 367 441 4.4E-22 T 06-07-2017 BWK49_RS11355 906114e68b166ac9ec2a79ecb7c41e3e 545 Gene3D G3DSA:3.30.300.30 443 539 1.3E-18 T 06-07-2017 BWK49_RS06145 20b223079b7d8e640be597a7d659846b 265 Gene3D G3DSA:1.10.1040.10 162 255 1.3E-12 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 BWK49_RS06145 20b223079b7d8e640be597a7d659846b 265 SUPERFAMILY SSF48179 159 259 3.85E-15 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 BWK49_RS06145 20b223079b7d8e640be597a7d659846b 265 PIRSF PIRSF000103 1 264 4.2E-52 T 06-07-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 BWK49_RS06145 20b223079b7d8e640be597a7d659846b 265 SUPERFAMILY SSF51735 2 158 4.48E-34 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS06145 20b223079b7d8e640be597a7d659846b 265 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 157 9.1E-32 T 06-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 BWK49_RS06145 20b223079b7d8e640be597a7d659846b 265 Gene3D G3DSA:3.40.50.720 2 161 1.8E-40 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS06145 20b223079b7d8e640be597a7d659846b 265 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 160 256 9.8E-12 T 06-07-2017 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 BWK49_RS03785 f82e0cc18a5d52df02889fdade1f4b55 69 Pfam PF13459 4Fe-4S single cluster domain 7 64 1.4E-11 T 06-07-2017 BWK49_RS03785 f82e0cc18a5d52df02889fdade1f4b55 69 SUPERFAMILY SSF54862 5 64 2.74E-11 T 06-07-2017 BWK49_RS03785 f82e0cc18a5d52df02889fdade1f4b55 69 Gene3D G3DSA:3.30.70.20 5 68 2.9E-15 T 06-07-2017 BWK49_RS25865 7eec8c7b6cb8604769dbd59b902ecced 255 SUPERFAMILY SSF52266 2 255 4.5E-64 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain BWK49_RS25865 7eec8c7b6cb8604769dbd59b902ecced 255 Gene3D G3DSA:3.40.50.1110 2 255 1.4E-50 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain BWK49_RS25865 7eec8c7b6cb8604769dbd59b902ecced 255 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 6 244 8.6E-24 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain BWK49_RS07210 00b875ef00e9fd531dc350ee77096e52 202 Pfam PF13580 SIS domain 35 154 1.3E-26 T 06-07-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 BWK49_RS07210 00b875ef00e9fd531dc350ee77096e52 202 Hamap MF_00067 Phosphoheptose isomerase [gmhA]. 9 197 33.605 T 06-07-2017 IPR004515 Phosphoheptose isomerase GO:0005737|GO:0008968 KEGG: 00540+5.3.1.28|MetaCyc: PWY-6478 BWK49_RS07210 00b875ef00e9fd531dc350ee77096e52 202 SUPERFAMILY SSF53697 12 198 2.02E-49 T 06-07-2017 BWK49_RS07210 00b875ef00e9fd531dc350ee77096e52 202 Gene3D G3DSA:3.40.50.10490 13 198 6.4E-58 T 06-07-2017 BWK49_RS10720 50e9b7f0a6d8ceaca0bb9360dd322e1a 508 SUPERFAMILY SSF140459 5 177 7.06E-62 T 06-07-2017 BWK49_RS10720 50e9b7f0a6d8ceaca0bb9360dd322e1a 508 Pfam PF00823 PPE family 8 164 7.8E-60 T 06-07-2017 IPR000030 PPE family BWK49_RS01100 4503c027c2c4b2ea6a291d6ccabe209a 256 Pfam PF01553 Acyltransferase 22 150 8.7E-32 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 BWK49_RS01100 4503c027c2c4b2ea6a291d6ccabe209a 256 SUPERFAMILY SSF69593 14 204 1.06E-33 T 06-07-2017 BWK49_RS01100 4503c027c2c4b2ea6a291d6ccabe209a 256 SMART SM00563 37 153 2.0E-34 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 BWK49_RS01100 4503c027c2c4b2ea6a291d6ccabe209a 256 Gene3D G3DSA:3.40.1130.10 26 207 2.4E-19 T 06-07-2017 BWK49_RS16460 f74c745e1e6c486bf24df5307653a3b4 96 Pfam PF02583 Metal-sensitive transcriptional repressor 11 91 2.6E-30 T 06-07-2017 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 BWK49_RS13280 09a380a0eee4825002dbd4892b4b6a6d 284 Gene3D G3DSA:1.10.357.10 56 233 1.2E-35 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS13280 09a380a0eee4825002dbd4892b4b6a6d 284 Pfam PF00440 Bacterial regulatory proteins, tetR family 67 113 6.6E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS13280 09a380a0eee4825002dbd4892b4b6a6d 284 SUPERFAMILY SSF48498 137 233 1.02E-15 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS13280 09a380a0eee4825002dbd4892b4b6a6d 284 SUPERFAMILY SSF46689 53 137 9.75E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS13280 09a380a0eee4825002dbd4892b4b6a6d 284 Pfam PF13305 WHG domain 141 231 5.8E-15 T 06-07-2017 IPR025996 WHG domain BWK49_RS17095 6bc30be4c5918877102c874415920913 472 SUPERFAMILY SSF103473 13 202 2.88E-31 T 06-07-2017 IPR020846 Major facilitator superfamily domain BWK49_RS17095 6bc30be4c5918877102c874415920913 472 SUPERFAMILY SSF103473 253 464 2.88E-31 T 06-07-2017 IPR020846 Major facilitator superfamily domain BWK49_RS17095 6bc30be4c5918877102c874415920913 472 Gene3D G3DSA:1.20.1250.20 21 192 1.4E-15 T 06-07-2017 BWK49_RS17095 6bc30be4c5918877102c874415920913 472 Gene3D G3DSA:1.20.1250.20 278 464 1.1E-7 T 06-07-2017 BWK49_RS17095 6bc30be4c5918877102c874415920913 472 Pfam PF07690 Major Facilitator Superfamily 28 419 7.4E-35 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 BWK49_RS00695 3b8aa06f3a1aa15bbda228ee736e1127 515 Pfam PF00916 Sulfate permease family 18 368 1.5E-71 T 06-07-2017 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 BWK49_RS18200 9345ff12786bf6b3571f5a262a5e4740 308 Pfam PF01040 UbiA prenyltransferase family 35 283 6.1E-61 T 06-07-2017 IPR000537 UbiA prenyltransferase family GO:0004659|GO:0016021 BWK49_RS18200 9345ff12786bf6b3571f5a262a5e4740 308 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 22 300 2.5E-98 T 06-07-2017 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 BWK49_RS18200 9345ff12786bf6b3571f5a262a5e4740 308 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 19 301 18.767 T 06-07-2017 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 BWK49_RS06435 aaf0ea46557fe2d04769558a95768e29 251 Pfam PF00378 Enoyl-CoA hydratase/isomerase 6 205 1.6E-39 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 BWK49_RS06435 aaf0ea46557fe2d04769558a95768e29 251 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 95 115 - T 06-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 BWK49_RS06435 aaf0ea46557fe2d04769558a95768e29 251 SUPERFAMILY SSF52096 2 210 5.13E-52 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS06435 aaf0ea46557fe2d04769558a95768e29 251 Gene3D G3DSA:3.90.226.10 2 207 1.0E-54 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS01555 a1d275ee650d33e154e513821265f79f 147 SUPERFAMILY SSF50249 6 133 1.71E-31 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS01555 a1d275ee650d33e154e513821265f79f 147 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 59 123 1.8E-18 T 06-07-2017 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal BWK49_RS01555 a1d275ee650d33e154e513821265f79f 147 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 23 57 8.2E-8 T 06-07-2017 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal BWK49_RS25420 5038a6ef2865d93c3635d8e038ea19c3 308 Pfam PF11209 Protein of unknown function (DUF2993) 89 285 3.3E-15 T 06-07-2017 IPR021373 Protein of unknown function DUF2993 BWK49_RS15065 a8b0aab76f29cce8b60f17a724c52b3d 214 SUPERFAMILY SSF48498 91 178 2.86E-8 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS15065 a8b0aab76f29cce8b60f17a724c52b3d 214 SUPERFAMILY SSF46689 21 95 9.98E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS15065 a8b0aab76f29cce8b60f17a724c52b3d 214 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 68 3.7E-15 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS15065 a8b0aab76f29cce8b60f17a724c52b3d 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 1.4E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS15065 a8b0aab76f29cce8b60f17a724c52b3d 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 38 1.4E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS15065 a8b0aab76f29cce8b60f17a724c52b3d 214 Gene3D G3DSA:1.10.357.10 23 202 4.5E-32 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS13655 4b824b43fa71d1afc58a55a04a96b22c 264 Gene3D G3DSA:3.40.50.300 17 175 3.4E-33 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS13655 4b824b43fa71d1afc58a55a04a96b22c 264 SUPERFAMILY SSF52540 11 225 2.19E-32 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS13655 4b824b43fa71d1afc58a55a04a96b22c 264 Pfam PF07728 AAA domain (dynein-related subfamily) 25 159 2.0E-35 T 06-07-2017 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 BWK49_RS13655 4b824b43fa71d1afc58a55a04a96b22c 264 Pfam PF08406 CbbQ/NirQ/NorQ C-terminal 172 255 7.1E-20 T 06-07-2017 IPR013615 CbbQ/NirQ/NorQ, C-terminal BWK49_RS15265 58af639744cf8abffb1715c49043e234 417 Pfam PF00823 PPE family 5 161 1.4E-63 T 06-07-2017 IPR000030 PPE family BWK49_RS15265 58af639744cf8abffb1715c49043e234 417 SUPERFAMILY SSF140459 2 174 1.36E-65 T 06-07-2017 BWK49_RS15265 58af639744cf8abffb1715c49043e234 417 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 329 413 2.4E-16 T 06-07-2017 IPR022171 PPE family, C-terminal BWK49_RS13755 3ee1431045d70423d1b13f6f1fbe4f2a 116 Pfam PF13564 DoxX-like family 7 108 2.8E-19 T 06-07-2017 IPR032808 DoxX family BWK49_RS24605 12501af640a14e2b779a182fd29927d8 166 PIRSF PIRSF018072 1 150 1.4E-52 T 06-07-2017 IPR016709 Uncharacterised protein family UPF0336 BWK49_RS24605 12501af640a14e2b779a182fd29927d8 166 Pfam PF13452 N-terminal half of MaoC dehydratase 15 137 1.0E-22 T 06-07-2017 BWK49_RS24605 12501af640a14e2b779a182fd29927d8 166 Gene3D G3DSA:3.10.129.10 16 143 6.5E-19 T 06-07-2017 IPR029069 HotDog domain BWK49_RS24605 12501af640a14e2b779a182fd29927d8 166 Hamap MF_00799 UPF0336 protein . 1 148 31.853 T 06-07-2017 IPR016709 Uncharacterised protein family UPF0336 BWK49_RS24605 12501af640a14e2b779a182fd29927d8 166 SUPERFAMILY SSF54637 15 144 1.91E-29 T 06-07-2017 IPR029069 HotDog domain BWK49_RS11560 7addf5eaa5a9bc6f18dde71fd9686e02 227 PIRSF PIRSF000441 1 213 2.4E-78 T 06-07-2017 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 BWK49_RS11560 7addf5eaa5a9bc6f18dde71fd9686e02 227 TIGRFAM TIGR01172 cysE: serine O-acetyltransferase 5 166 1.2E-73 T 06-07-2017 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 BWK49_RS11560 7addf5eaa5a9bc6f18dde71fd9686e02 227 Gene3D G3DSA:2.160.10.10 64 170 3.7E-33 T 06-07-2017 BWK49_RS11560 7addf5eaa5a9bc6f18dde71fd9686e02 227 Gene3D G3DSA:1.10.3130.10 1 63 7.7E-26 T 06-07-2017 BWK49_RS11560 7addf5eaa5a9bc6f18dde71fd9686e02 227 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 117 150 5.9E-9 T 06-07-2017 IPR001451 Hexapeptide repeat BWK49_RS11560 7addf5eaa5a9bc6f18dde71fd9686e02 227 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 69 108 1.2E-4 T 06-07-2017 IPR001451 Hexapeptide repeat BWK49_RS11560 7addf5eaa5a9bc6f18dde71fd9686e02 227 Pfam PF06426 Serine acetyltransferase, N-terminal 2 35 5.8E-5 T 06-07-2017 IPR010493 Serine acetyltransferase, N-terminal GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 BWK49_RS11560 7addf5eaa5a9bc6f18dde71fd9686e02 227 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 126 154 - T 06-07-2017 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 BWK49_RS11560 7addf5eaa5a9bc6f18dde71fd9686e02 227 SUPERFAMILY SSF51161 5 170 3.19E-53 T 06-07-2017 IPR011004 Trimeric LpxA-like BWK49_RS16140 eda06d2e069b0bb06f5fe112fd4ed746 532 Pfam PF01566 Natural resistance-associated macrophage protein 55 408 5.6E-77 T 06-07-2017 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 BWK49_RS21390 eff4d01c0a9837b86c5201f9649dd758 330 Pfam PF14417 MEDS: MEthanogen/methylotroph, DcmR Sensory domain 22 167 3.9E-27 T 06-07-2017 IPR025847 MEDS domain BWK49_RS21390 eff4d01c0a9837b86c5201f9649dd758 330 SUPERFAMILY SSF55874 216 319 4.73E-6 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS21390 eff4d01c0a9837b86c5201f9649dd758 330 Pfam PF13581 Histidine kinase-like ATPase domain 209 317 2.3E-8 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain BWK49_RS17690 374a1c14c79e76efea25b93688afce23 216 SUPERFAMILY SSF53335 36 101 9.11E-8 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS17690 374a1c14c79e76efea25b93688afce23 216 Gene3D G3DSA:3.40.50.150 32 201 6.0E-37 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS05155 998779f01c67f3b9ff6f2dfdea1ae375 298 SUPERFAMILY SSF53474 3 292 2.68E-42 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS05155 998779f01c67f3b9ff6f2dfdea1ae375 298 Gene3D G3DSA:3.40.50.1820 6 292 2.9E-54 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS05155 998779f01c67f3b9ff6f2dfdea1ae375 298 Pfam PF12697 Alpha/beta hydrolase family 30 284 1.1E-16 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS14140 dbd054fd9f55335b9b92f661faa9d083 263 SUPERFAMILY SSF161098 56 243 2.09E-26 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS14140 dbd054fd9f55335b9b92f661faa9d083 263 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 79 253 1.8E-15 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS14140 dbd054fd9f55335b9b92f661faa9d083 263 Gene3D G3DSA:1.10.3720.10 53 252 5.0E-20 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS12370 4ccd33c6c3b978443e9bfd55b9696c27 361 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 8 86 1.8E-7 T 06-07-2017 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 BWK49_RS12370 4ccd33c6c3b978443e9bfd55b9696c27 361 SUPERFAMILY SSF51735 8 149 2.08E-14 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS12370 4ccd33c6c3b978443e9bfd55b9696c27 361 Gene3D G3DSA:3.40.50.720 7 210 2.2E-22 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS24825 9cea13b8323e62f64918444df826a8a7 493 Pfam PF00916 Sulfate permease family 6 358 1.5E-71 T 06-07-2017 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 BWK49_RS15140 065367dc1863d2d818ad37ef946f6618 167 Gene3D G3DSA:3.10.180.10 11 138 6.5E-11 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS15140 065367dc1863d2d818ad37ef946f6618 167 SUPERFAMILY SSF54593 10 138 9.87E-14 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS15140 065367dc1863d2d818ad37ef946f6618 167 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 134 8.6E-23 T 06-07-2017 BWK49_RS21195 2ce10fb9f5c9ee56b95ab4877be9cad2 188 SMART SM00347 37 141 4.2E-12 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 BWK49_RS21195 2ce10fb9f5c9ee56b95ab4877be9cad2 188 Pfam PF12802 MarR family 45 104 5.2E-13 T 06-07-2017 BWK49_RS21195 2ce10fb9f5c9ee56b95ab4877be9cad2 188 Gene3D G3DSA:1.10.10.10 14 157 1.2E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS21195 2ce10fb9f5c9ee56b95ab4877be9cad2 188 SUPERFAMILY SSF46785 13 158 2.78E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS02895 afd83eadb3330814cfc0b60c5bda81f1 193 Pfam PF00482 Type II secretion system (T2SS), protein F 48 173 1.1E-16 T 06-07-2017 IPR018076 Type II secretion system F domain BWK49_RS14000 4f15b8e27b2a8e89853b21b9762320f5 316 Pfam PF01734 Patatin-like phospholipase 9 189 9.6E-31 T 06-07-2017 IPR002641 Patatin/Phospholipase A2-related GO:0006629 BWK49_RS14000 4f15b8e27b2a8e89853b21b9762320f5 316 SUPERFAMILY SSF52151 6 271 2.33E-51 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 BWK49_RS14000 4f15b8e27b2a8e89853b21b9762320f5 316 Gene3D G3DSA:3.40.1090.10 3 283 4.1E-74 T 06-07-2017 BWK49_RS14595 3b9eab4b4f4efde1c1e179ae5de2af78 199 Gene3D G3DSA:1.10.357.10 65 194 8.3E-22 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS14595 3b9eab4b4f4efde1c1e179ae5de2af78 199 ProSitePatterns PS01081 TetR-type HTH domain signature. 31 62 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site BWK49_RS14595 3b9eab4b4f4efde1c1e179ae5de2af78 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 62 1.1E-14 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS14595 3b9eab4b4f4efde1c1e179ae5de2af78 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 4.1E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS14595 3b9eab4b4f4efde1c1e179ae5de2af78 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 4.1E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS14595 3b9eab4b4f4efde1c1e179ae5de2af78 199 Gene3D G3DSA:1.10.10.60 8 64 4.9E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS14595 3b9eab4b4f4efde1c1e179ae5de2af78 199 SUPERFAMILY SSF46689 7 80 8.48E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS23275 a1df978de8d25bca86b77842d9fd896e 119 Pfam PF05305 Protein of unknown function (DUF732) 23 113 4.5E-26 T 06-07-2017 IPR007969 Domain of unknown function DUF732 BWK49_RS23635 76fd0e5421e0a346f48d0933c0b1e4a6 295 PIRSF PIRSF003085 3 295 2.0E-115 T 06-07-2017 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 BWK49_RS23635 76fd0e5421e0a346f48d0933c0b1e4a6 295 SUPERFAMILY SSF53335 21 295 5.47E-77 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS23635 76fd0e5421e0a346f48d0933c0b1e4a6 295 Pfam PF02353 Mycolic acid cyclopropane synthetase 13 291 2.8E-125 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS23635 76fd0e5421e0a346f48d0933c0b1e4a6 295 Gene3D G3DSA:3.40.50.150 15 295 8.0E-89 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS03875 6d1f834737e670ca6d08bc4e4143d136 415 PRINTS PR00385 P450 superfamily signature 354 363 9.8E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS03875 6d1f834737e670ca6d08bc4e4143d136 415 PRINTS PR00385 P450 superfamily signature 253 270 9.8E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS03875 6d1f834737e670ca6d08bc4e4143d136 415 PRINTS PR00385 P450 superfamily signature 363 374 9.8E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS03875 6d1f834737e670ca6d08bc4e4143d136 415 Gene3D G3DSA:1.10.630.10 8 413 3.8E-106 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS03875 6d1f834737e670ca6d08bc4e4143d136 415 Pfam PF00067 Cytochrome P450 212 384 6.0E-24 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS03875 6d1f834737e670ca6d08bc4e4143d136 415 PRINTS PR00359 B-class P450 signature 161 176 3.2E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS03875 6d1f834737e670ca6d08bc4e4143d136 415 PRINTS PR00359 B-class P450 signature 305 332 3.2E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS03875 6d1f834737e670ca6d08bc4e4143d136 415 PRINTS PR00359 B-class P450 signature 288 299 3.2E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS03875 6d1f834737e670ca6d08bc4e4143d136 415 PRINTS PR00359 B-class P450 signature 144 160 3.2E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS03875 6d1f834737e670ca6d08bc4e4143d136 415 PRINTS PR00359 B-class P450 signature 363 374 3.2E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS03875 6d1f834737e670ca6d08bc4e4143d136 415 PRINTS PR00359 B-class P450 signature 333 348 3.2E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS03875 6d1f834737e670ca6d08bc4e4143d136 415 PRINTS PR00359 B-class P450 signature 204 226 3.2E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS03875 6d1f834737e670ca6d08bc4e4143d136 415 PRINTS PR00359 B-class P450 signature 354 363 3.2E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS03875 6d1f834737e670ca6d08bc4e4143d136 415 PRINTS PR00359 B-class P450 signature 98 109 3.2E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS03875 6d1f834737e670ca6d08bc4e4143d136 415 SUPERFAMILY SSF48264 20 407 5.76E-85 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS03875 6d1f834737e670ca6d08bc4e4143d136 415 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 356 365 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 BWK49_RS20535 f9e02e42f22f9bb1bdc4188967cc403b 307 Gene3D G3DSA:1.20.1510.10 25 219 1.6E-56 T 06-07-2017 IPR027469 Cation efflux protein transmembrane domain BWK49_RS20535 f9e02e42f22f9bb1bdc4188967cc403b 307 SUPERFAMILY SSF160240 223 299 6.28E-10 T 06-07-2017 BWK49_RS20535 f9e02e42f22f9bb1bdc4188967cc403b 307 Pfam PF01545 Cation efflux family 28 219 1.4E-45 T 06-07-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 BWK49_RS20535 f9e02e42f22f9bb1bdc4188967cc403b 307 SUPERFAMILY SSF161111 23 220 1.09E-55 T 06-07-2017 BWK49_RS20535 f9e02e42f22f9bb1bdc4188967cc403b 307 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 26 299 4.0E-85 T 06-07-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 BWK49_RS20535 f9e02e42f22f9bb1bdc4188967cc403b 307 Gene3D G3DSA:3.30.70.1350 234 299 8.6E-4 T 06-07-2017 IPR027470 Cation efflux protein, cytoplasmic domain BWK49_RS14905 3a5ba22964fb4d220975012f4cdece2e 307 Pfam PF02673 Bacitracin resistance protein BacA 10 298 2.9E-66 T 06-07-2017 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 BWK49_RS14905 3a5ba22964fb4d220975012f4cdece2e 307 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 5 304 15.842 T 06-07-2017 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 BWK49_RS15950 53f542f83d367c71592c7fe095e0acc0 596 Gene3D G3DSA:3.30.470.20 409 447 1.8E-14 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 BWK49_RS15950 53f542f83d367c71592c7fe095e0acc0 596 Gene3D G3DSA:3.30.470.20 319 336 1.8E-14 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 BWK49_RS15950 53f542f83d367c71592c7fe095e0acc0 596 Gene3D G3DSA:3.30.470.20 489 576 1.8E-14 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 BWK49_RS15950 53f542f83d367c71592c7fe095e0acc0 596 SUPERFAMILY SSF55729 54 248 1.05E-19 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase BWK49_RS15950 53f542f83d367c71592c7fe095e0acc0 596 Gene3D G3DSA:3.40.630.30 112 249 8.7E-18 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase BWK49_RS15950 53f542f83d367c71592c7fe095e0acc0 596 Pfam PF00583 Acetyltransferase (GNAT) family 162 244 1.4E-13 T 06-07-2017 IPR000182 GNAT domain GO:0008080 BWK49_RS15950 53f542f83d367c71592c7fe095e0acc0 596 Gene3D G3DSA:3.30.1490.20 340 408 1.2E-6 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 BWK49_RS15950 53f542f83d367c71592c7fe095e0acc0 596 SUPERFAMILY SSF56059 490 572 5.77E-25 T 06-07-2017 BWK49_RS15950 53f542f83d367c71592c7fe095e0acc0 596 SUPERFAMILY SSF56059 329 441 5.77E-25 T 06-07-2017 BWK49_RS15950 53f542f83d367c71592c7fe095e0acc0 596 Pfam PF08443 RimK-like ATP-grasp domain 328 432 8.6E-5 T 06-07-2017 IPR013651 ATP-grasp fold, RimK-type BWK49_RS15950 53f542f83d367c71592c7fe095e0acc0 596 Pfam PF08443 RimK-like ATP-grasp domain 499 563 5.8E-5 T 06-07-2017 IPR013651 ATP-grasp fold, RimK-type BWK49_RS15950 53f542f83d367c71592c7fe095e0acc0 596 TIGRFAM TIGR03103 trio_acet_GNAT: GNAT-family acetyltransferase TIGR03103 30 580 1.2E-271 T 06-07-2017 IPR017534 GNAT-acetyltransferase BWK49_RS19145 12a31d7c8af1c21d24d96a22660576e8 643 Pfam PF06259 Alpha/beta hydrolase 338 511 2.9E-33 T 06-07-2017 IPR010427 Protein of unknown function DUF1023 BWK49_RS19145 12a31d7c8af1c21d24d96a22660576e8 643 Gene3D G3DSA:3.40.50.1820 420 521 2.9E-7 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS19145 12a31d7c8af1c21d24d96a22660576e8 643 SUPERFAMILY SSF53474 355 490 5.29E-5 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS06490 a264276c8d16bec0f13c52491f2ac480 393 SUPERFAMILY SSF53383 4 389 3.09E-104 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase BWK49_RS06490 a264276c8d16bec0f13c52491f2ac480 393 Gene3D G3DSA:3.90.1150.10 251 389 1.7E-28 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 BWK49_RS06490 a264276c8d16bec0f13c52491f2ac480 393 Gene3D G3DSA:3.40.640.10 39 250 2.5E-72 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 BWK49_RS06490 a264276c8d16bec0f13c52491f2ac480 393 Pfam PF00155 Aminotransferase class I and II 27 386 2.2E-60 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 BWK49_RS16640 c8771168f09cf283f89e4cb56f1252ca 583 Hamap MF_01227 CTP synthase [pyrG]. 9 549 48.842 T 06-07-2017 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 BWK49_RS16640 c8771168f09cf283f89e4cb56f1252ca 583 SUPERFAMILY SSF52317 301 549 5.53E-70 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like BWK49_RS16640 c8771168f09cf283f89e4cb56f1252ca 583 Gene3D G3DSA:3.40.50.880 299 549 8.2E-86 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like BWK49_RS16640 c8771168f09cf283f89e4cb56f1252ca 583 Gene3D G3DSA:3.40.50.300 5 296 2.3E-129 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS16640 c8771168f09cf283f89e4cb56f1252ca 583 Pfam PF06418 CTP synthase N-terminus 10 278 9.1E-121 T 06-07-2017 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 BWK49_RS16640 c8771168f09cf283f89e4cb56f1252ca 583 SUPERFAMILY SSF52540 9 278 6.64E-117 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS16640 c8771168f09cf283f89e4cb56f1252ca 583 Pfam PF00117 Glutamine amidotransferase class-I 313 542 6.3E-45 T 06-07-2017 IPR017926 Glutamine amidotransferase BWK49_RS16640 c8771168f09cf283f89e4cb56f1252ca 583 TIGRFAM TIGR00337 PyrG: CTP synthase 9 544 5.3E-222 T 06-07-2017 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 BWK49_RS12880 53b13322e76c767cbbc1bad895c2722c 310 Pfam PF05423 Mycobacterium membrane protein 216 298 5.6E-7 T 06-07-2017 IPR008693 Transport accessory protein MmpS BWK49_RS12880 53b13322e76c767cbbc1bad895c2722c 310 PRINTS PR01217 Proline rich extensin signature 179 195 1.5E-9 T 06-07-2017 BWK49_RS12880 53b13322e76c767cbbc1bad895c2722c 310 PRINTS PR01217 Proline rich extensin signature 197 214 1.5E-9 T 06-07-2017 BWK49_RS12880 53b13322e76c767cbbc1bad895c2722c 310 PRINTS PR01217 Proline rich extensin signature 158 179 1.5E-9 T 06-07-2017 BWK49_RS12880 53b13322e76c767cbbc1bad895c2722c 310 PRINTS PR01217 Proline rich extensin signature 140 152 1.5E-9 T 06-07-2017 BWK49_RS05180 efd55db964f2fccfd856af1e838c006c 433 SUPERFAMILY SSF48264 34 431 1.31E-83 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS05180 efd55db964f2fccfd856af1e838c006c 433 Pfam PF00067 Cytochrome P450 231 401 1.0E-14 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS05180 efd55db964f2fccfd856af1e838c006c 433 PRINTS PR00359 B-class P450 signature 178 193 1.1E-38 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS05180 efd55db964f2fccfd856af1e838c006c 433 PRINTS PR00359 B-class P450 signature 305 316 1.1E-38 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS05180 efd55db964f2fccfd856af1e838c006c 433 PRINTS PR00359 B-class P450 signature 372 381 1.1E-38 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS05180 efd55db964f2fccfd856af1e838c006c 433 PRINTS PR00359 B-class P450 signature 350 365 1.1E-38 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS05180 efd55db964f2fccfd856af1e838c006c 433 PRINTS PR00359 B-class P450 signature 322 349 1.1E-38 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS05180 efd55db964f2fccfd856af1e838c006c 433 PRINTS PR00359 B-class P450 signature 161 177 1.1E-38 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS05180 efd55db964f2fccfd856af1e838c006c 433 PRINTS PR00359 B-class P450 signature 223 245 1.1E-38 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS05180 efd55db964f2fccfd856af1e838c006c 433 PRINTS PR00359 B-class P450 signature 115 126 1.1E-38 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS05180 efd55db964f2fccfd856af1e838c006c 433 PRINTS PR00359 B-class P450 signature 381 392 1.1E-38 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS05180 efd55db964f2fccfd856af1e838c006c 433 Gene3D G3DSA:1.10.630.10 33 431 1.8E-106 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS03910 5cbadd2e491906f322d421696425322f 234 Pfam PF10096 Uncharacterized protein conserved in bacteria (DUF2334) 15 138 2.0E-15 T 06-07-2017 IPR018763 Protein of unknown function DUF2334 BWK49_RS03910 5cbadd2e491906f322d421696425322f 234 SUPERFAMILY SSF88713 32 146 1.33E-5 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 BWK49_RS09975 f472330b5a335f4801d35002e4eb45be 116 Pfam PF14017 Protein of unknown function (DUF4233) 16 115 3.2E-24 T 06-07-2017 IPR025327 Protein of unknown function DUF4233 BWK49_RS05945 0186bab26e29a4715da408c056035df8 240 Gene3D G3DSA:3.40.50.720 3 236 9.0E-77 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS05945 0186bab26e29a4715da408c056035df8 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 7.2E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05945 0186bab26e29a4715da408c056035df8 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 201 221 7.2E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05945 0186bab26e29a4715da408c056035df8 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 7.2E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05945 0186bab26e29a4715da408c056035df8 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 185 7.2E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05945 0186bab26e29a4715da408c056035df8 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 137 7.2E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05945 0186bab26e29a4715da408c056035df8 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 166 7.2E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05945 0186bab26e29a4715da408c056035df8 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 74 85 1.1E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05945 0186bab26e29a4715da408c056035df8 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 147 166 1.1E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05945 0186bab26e29a4715da408c056035df8 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 127 135 1.1E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS05945 0186bab26e29a4715da408c056035df8 240 SUPERFAMILY SSF51735 7 236 1.25E-75 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS05945 0186bab26e29a4715da408c056035df8 240 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 236 7.0E-57 T 06-07-2017 BWK49_RS01210 a5fde03370b8742afa0cd40fabacb44a 1108 Pfam PF04602 Mycobacterial cell wall arabinan synthesis protein 11 679 2.0E-258 T 06-07-2017 IPR007680 Arabinofuranosyltransferase, N-terminal GO:0052636|GO:0071766 BWK49_RS01210 a5fde03370b8742afa0cd40fabacb44a 1108 Pfam PF14896 EmbC C-terminal domain 714 1105 1.5E-150 T 06-07-2017 IPR032731 Arabinosyltransferase, C-terminal BWK49_RS01210 a5fde03370b8742afa0cd40fabacb44a 1108 Gene3D G3DSA:2.60.120.610 32 204 1.2E-57 T 06-07-2017 IPR027451 Arabinofuranosyltransferase, domain 1 BWK49_RS09640 29cf8163fb5ccbe01d2d4099fd8c1e91 157 Pfam PF00578 AhpC/TSA family 10 136 5.8E-41 T 06-07-2017 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 BWK49_RS09640 29cf8163fb5ccbe01d2d4099fd8c1e91 157 SUPERFAMILY SSF52833 6 155 6.67E-50 T 06-07-2017 IPR012336 Thioredoxin-like fold BWK49_RS09640 29cf8163fb5ccbe01d2d4099fd8c1e91 157 PIRSF PIRSF000239 2 155 1.3E-20 T 06-07-2017 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 BWK49_RS09640 29cf8163fb5ccbe01d2d4099fd8c1e91 157 Gene3D G3DSA:3.40.30.10 3 155 2.2E-52 T 06-07-2017 IPR012336 Thioredoxin-like fold BWK49_RS07765 e92f824f9472e1ca87a4f687029447ff 127 Pfam PF12680 SnoaL-like domain 14 113 1.2E-13 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain BWK49_RS07765 e92f824f9472e1ca87a4f687029447ff 127 SUPERFAMILY SSF54427 7 122 2.83E-26 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS07765 e92f824f9472e1ca87a4f687029447ff 127 Gene3D G3DSA:3.10.450.50 6 123 2.1E-31 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS01145 59762b8902c49aac36ca612eb3842d43 308 Pfam PF01040 UbiA prenyltransferase family 59 272 3.5E-20 T 06-07-2017 IPR000537 UbiA prenyltransferase family GO:0004659|GO:0016021 BWK49_RS23585 c8caea1bc288eba79a8714635ace9c2f 133 SUPERFAMILY SSF103196 3 128 7.19E-33 T 06-07-2017 BWK49_RS23585 c8caea1bc288eba79a8714635ace9c2f 133 SMART SM00960 9 99 1.5E-31 T 06-07-2017 IPR004942 Roadblock/LAMTOR2 domain BWK49_RS23585 c8caea1bc288eba79a8714635ace9c2f 133 Gene3D G3DSA:3.30.450.30 5 125 3.0E-26 T 06-07-2017 BWK49_RS23585 c8caea1bc288eba79a8714635ace9c2f 133 Pfam PF03259 Roadblock/LC7 domain 8 98 8.2E-25 T 06-07-2017 IPR004942 Roadblock/LAMTOR2 domain BWK49_RS07805 eec2cae19ba433332c30033b19e56329 433 SUPERFAMILY SSF52540 220 383 2.02E-20 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS07805 eec2cae19ba433332c30033b19e56329 433 SUPERFAMILY SSF52540 166 175 2.02E-20 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS07805 eec2cae19ba433332c30033b19e56329 433 Pfam PF02562 PhoH-like protein 222 426 6.0E-52 T 06-07-2017 IPR003714 PhoH-like protein GO:0005524 BWK49_RS07805 eec2cae19ba433332c30033b19e56329 433 SMART SM00670 5 132 8.4E-21 T 06-07-2017 IPR002716 PIN domain BWK49_RS07805 eec2cae19ba433332c30033b19e56329 433 Gene3D G3DSA:3.40.50.1010 97 141 2.7E-10 T 06-07-2017 IPR029060 PIN domain-like BWK49_RS07805 eec2cae19ba433332c30033b19e56329 433 Gene3D G3DSA:3.40.50.1010 6 64 2.7E-10 T 06-07-2017 IPR029060 PIN domain-like BWK49_RS07805 eec2cae19ba433332c30033b19e56329 433 Pfam PF13638 PIN domain 7 145 4.6E-28 T 06-07-2017 IPR002716 PIN domain BWK49_RS07805 eec2cae19ba433332c30033b19e56329 433 Gene3D G3DSA:3.40.50.300 220 426 2.7E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS07805 eec2cae19ba433332c30033b19e56329 433 SUPERFAMILY SSF88723 97 140 3.79E-9 T 06-07-2017 IPR029060 PIN domain-like BWK49_RS07805 eec2cae19ba433332c30033b19e56329 433 SUPERFAMILY SSF88723 6 64 3.79E-9 T 06-07-2017 IPR029060 PIN domain-like BWK49_RS06660 a6269ae001cc0653e99d19b824f38fe4 92 ProDom PD053583 TRANSMEMBRANE MEMBRANE PRECURSOR SIGNAL MB0906 RV0882/MT0905 2 68 3.0E-8 T 06-07-2017 IPR024244 Protein of unknown function DUF2537 BWK49_RS06660 a6269ae001cc0653e99d19b824f38fe4 92 Pfam PF10801 Protein of unknown function (DUF2537) 7 85 8.1E-29 T 06-07-2017 IPR024244 Protein of unknown function DUF2537 BWK49_RS21695 d5e01fa0dcf7ebe4bba2205e842d6608 107 Pfam PF05305 Protein of unknown function (DUF732) 2 97 3.1E-26 T 06-07-2017 IPR007969 Domain of unknown function DUF732 BWK49_RS17365 f99b29b5058ccf17f6004e072fa80bb6 446 PIRSF PIRSF029171 22 408 4.2E-33 T 06-07-2017 IPR005152 Lipase, secreted GO:0004806|GO:0016042 KEGG: 00561+3.1.1.3|MetaCyc: PWY-6857 BWK49_RS17365 f99b29b5058ccf17f6004e072fa80bb6 446 Gene3D G3DSA:3.40.50.1820 92 264 4.7E-16 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS17365 f99b29b5058ccf17f6004e072fa80bb6 446 Gene3D G3DSA:3.40.50.1820 326 390 4.7E-16 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS17365 f99b29b5058ccf17f6004e072fa80bb6 446 SUPERFAMILY SSF53474 92 239 3.77E-20 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS17365 f99b29b5058ccf17f6004e072fa80bb6 446 SUPERFAMILY SSF53474 298 398 3.77E-20 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS17365 f99b29b5058ccf17f6004e072fa80bb6 446 Pfam PF03583 Secretory lipase 129 406 9.9E-87 T 06-07-2017 IPR005152 Lipase, secreted GO:0004806|GO:0016042 KEGG: 00561+3.1.1.3|MetaCyc: PWY-6857 BWK49_RS05290 e8cbfd6c2e6e85eee65a77d1353709db 130 Pfam PF01850 PIN domain 4 119 8.1E-15 T 06-07-2017 IPR002716 PIN domain BWK49_RS05290 e8cbfd6c2e6e85eee65a77d1353709db 130 SUPERFAMILY SSF88723 4 127 8.13E-15 T 06-07-2017 IPR029060 PIN domain-like BWK49_RS05290 e8cbfd6c2e6e85eee65a77d1353709db 130 Gene3D G3DSA:3.40.50.1010 3 128 1.0E-10 T 06-07-2017 IPR029060 PIN domain-like BWK49_RS05290 e8cbfd6c2e6e85eee65a77d1353709db 130 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 4 126 13.198 T 06-07-2017 IPR022907 VapC family GO:0004540 BWK49_RS13700 5f0d5edd0ff160a9d3a7aa66d9404c4a 209 Gene3D G3DSA:1.10.357.10 8 193 2.6E-32 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS13700 5f0d5edd0ff160a9d3a7aa66d9404c4a 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 3.2E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS13700 5f0d5edd0ff160a9d3a7aa66d9404c4a 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 3.2E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS13700 5f0d5edd0ff160a9d3a7aa66d9404c4a 209 SUPERFAMILY SSF46689 7 87 1.28E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS13700 5f0d5edd0ff160a9d3a7aa66d9404c4a 209 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 65 1.5E-12 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS13700 5f0d5edd0ff160a9d3a7aa66d9404c4a 209 SUPERFAMILY SSF48498 86 184 2.26E-7 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS03310 6d6530e8813be9de63500216013e6288 381 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 231 370 3.9E-15 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS03310 6d6530e8813be9de63500216013e6288 381 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 120 1.5E-21 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS03310 6d6530e8813be9de63500216013e6288 381 SUPERFAMILY SSF56645 2 239 9.03E-63 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS03310 6d6530e8813be9de63500216013e6288 381 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 125 218 2.7E-16 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 BWK49_RS03310 6d6530e8813be9de63500216013e6288 381 Gene3D G3DSA:2.40.110.10 123 218 4.9E-25 T 06-07-2017 BWK49_RS03310 6d6530e8813be9de63500216013e6288 381 SUPERFAMILY SSF47203 230 374 3.7E-16 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS03310 6d6530e8813be9de63500216013e6288 381 Gene3D G3DSA:1.20.140.10 219 376 2.1E-25 T 06-07-2017 BWK49_RS03310 6d6530e8813be9de63500216013e6288 381 Gene3D G3DSA:1.10.540.10 4 122 4.7E-24 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS22680 3f221696fcc8d5a0b9dd635669ac8e50 381 Gene3D G3DSA:3.40.390.10 234 364 2.9E-6 T 06-07-2017 IPR024079 Metallopeptidase, catalytic domain GO:0008237 BWK49_RS22680 3f221696fcc8d5a0b9dd635669ac8e50 381 SUPERFAMILY SSF55486 164 379 3.84E-17 T 06-07-2017 BWK49_RS22680 3f221696fcc8d5a0b9dd635669ac8e50 381 Pfam PF11350 Protein of unknown function (DUF3152) 167 379 2.9E-102 T 06-07-2017 IPR022603 Domain of unknown function DUF3152 BWK49_RS22680 3f221696fcc8d5a0b9dd635669ac8e50 381 SMART SM00235 177 365 2.0E-5 T 06-07-2017 IPR006026 Peptidase, metallopeptidase GO:0006508|GO:0008237|GO:0008270 BWK49_RS10175 058dfb12b2eda9cfed06c9da3e467f80 325 Pfam PF04168 A predicted alpha-helical domain with a conserved ER motif. 1 301 2.6E-75 T 06-07-2017 IPR007296 Domain of unknown function DUF403 BWK49_RS26855 31e5ed920d22c666372758f56aa77828 157 Pfam PF03745 Domain of unknown function (DUF309) 48 104 3.6E-19 T 06-07-2017 IPR005500 Protein of unknown function DUF309 BWK49_RS26855 31e5ed920d22c666372758f56aa77828 157 Gene3D G3DSA:1.10.3450.10 45 148 1.0E-21 T 06-07-2017 IPR023203 TTHA0068-like domain BWK49_RS26855 31e5ed920d22c666372758f56aa77828 157 SUPERFAMILY SSF140663 30 147 3.27E-26 T 06-07-2017 IPR023203 TTHA0068-like domain BWK49_RS27075 40334d4457575b51928bac52afcfd2b9 392 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 27 332 5.5E-37 T 06-07-2017 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD BWK49_RS09935 b16980524be4480394d9171e3e5d136a 115 SUPERFAMILY SSF103473 41 90 3.14E-5 T 06-07-2017 IPR020846 Major facilitator superfamily domain BWK49_RS27105 3dcf357044e5521ea244d90186bdcee1 662 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 485 501 4.5E-23 T 06-07-2017 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 BWK49_RS27105 3dcf357044e5521ea244d90186bdcee1 662 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 464 476 4.5E-23 T 06-07-2017 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 BWK49_RS27105 3dcf357044e5521ea244d90186bdcee1 662 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 446 458 4.5E-23 T 06-07-2017 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 BWK49_RS27105 3dcf357044e5521ea244d90186bdcee1 662 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 559 570 4.5E-23 T 06-07-2017 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 BWK49_RS27105 3dcf357044e5521ea244d90186bdcee1 662 Pfam PF01431 Peptidase family M13 454 657 2.4E-76 T 06-07-2017 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 BWK49_RS27105 3dcf357044e5521ea244d90186bdcee1 662 Pfam PF05649 Peptidase family M13 21 402 1.8E-98 T 06-07-2017 IPR008753 Peptidase M13, N-terminal domain GO:0006508 BWK49_RS27105 3dcf357044e5521ea244d90186bdcee1 662 SUPERFAMILY SSF55486 8 661 5.49E-209 T 06-07-2017 BWK49_RS27105 3dcf357044e5521ea244d90186bdcee1 662 Gene3D G3DSA:3.40.390.10 445 661 4.7E-108 T 06-07-2017 IPR024079 Metallopeptidase, catalytic domain GO:0008237 BWK49_RS27105 3dcf357044e5521ea244d90186bdcee1 662 Gene3D G3DSA:3.40.390.10 284 405 4.7E-108 T 06-07-2017 IPR024079 Metallopeptidase, catalytic domain GO:0008237 BWK49_RS22440 62bb635415e2a1393f4532b0f055a8cf 142 Pfam PF14832 Putative oxalocrotonate tautomerase enzyme 1 132 9.8E-19 T 06-07-2017 IPR028116 Putative oxalocrotonate tautomerase BWK49_RS22440 62bb635415e2a1393f4532b0f055a8cf 142 SUPERFAMILY SSF55331 13 116 4.38E-9 T 06-07-2017 IPR014347 Tautomerase/MIF superfamily BWK49_RS22440 62bb635415e2a1393f4532b0f055a8cf 142 Gene3D G3DSA:3.30.429.10 1 132 7.2E-31 T 06-07-2017 BWK49_RS27025 724d7b8dc1692e73d5464856a092b62d 313 Pfam PF00378 Enoyl-CoA hydratase/isomerase 140 312 2.2E-31 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 BWK49_RS27025 724d7b8dc1692e73d5464856a092b62d 313 SUPERFAMILY SSF52096 131 312 1.34E-45 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS27025 724d7b8dc1692e73d5464856a092b62d 313 Gene3D G3DSA:3.90.226.10 132 312 2.3E-44 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS04080 b9a0d5d869380614503ff54bf15b612b 289 Pfam PF01063 Amino-transferase class IV 29 261 5.1E-39 T 06-07-2017 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 BWK49_RS04080 b9a0d5d869380614503ff54bf15b612b 289 SUPERFAMILY SSF56752 3 279 7.98E-50 T 06-07-2017 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 BWK49_RS04080 b9a0d5d869380614503ff54bf15b612b 289 Gene3D G3DSA:3.30.470.10 3 104 2.4E-20 T 06-07-2017 BWK49_RS04080 b9a0d5d869380614503ff54bf15b612b 289 Gene3D G3DSA:3.20.10.10 130 280 7.6E-26 T 06-07-2017 BWK49_RS00055 ad487b57fff816efe1794e52f6f046f0 143 SUPERFAMILY SSF54197 7 136 3.26E-22 T 06-07-2017 IPR011146 HIT-like domain GO:0003824 BWK49_RS00055 ad487b57fff816efe1794e52f6f046f0 143 Gene3D G3DSA:3.30.428.10 4 136 2.1E-23 T 06-07-2017 IPR011146 HIT-like domain GO:0003824 BWK49_RS28060 8020502bfaabbaef49a24b0700eca487 462 Pfam PF00756 Putative esterase 183 436 4.7E-10 T 06-07-2017 IPR000801 Putative esterase Reactome: R-HSA-156590 BWK49_RS28060 8020502bfaabbaef49a24b0700eca487 462 SUPERFAMILY SSF53474 159 444 3.65E-29 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS28060 8020502bfaabbaef49a24b0700eca487 462 Gene3D G3DSA:3.40.50.1820 157 447 3.5E-42 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS06365 51bfdb2b1dea4221013333c9d0f630d0 433 Pfam PF02470 MlaD protein 47 118 1.3E-9 T 06-07-2017 IPR003399 Mce/MlaD BWK49_RS06365 51bfdb2b1dea4221013333c9d0f630d0 433 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 167 297 1.3E-11 T 06-07-2017 IPR024516 Mammalian cell entry, C-terminal BWK49_RS06365 51bfdb2b1dea4221013333c9d0f630d0 433 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 15 296 1.3E-66 T 06-07-2017 IPR005693 Virulence factor Mce protein BWK49_RS28940 da626323fcacad792e3b44db4dcb3451 138 SUPERFAMILY SSF88723 2 127 2.52E-17 T 06-07-2017 IPR029060 PIN domain-like BWK49_RS28940 da626323fcacad792e3b44db4dcb3451 138 Gene3D G3DSA:3.40.50.1010 2 126 3.2E-4 T 06-07-2017 IPR029060 PIN domain-like BWK49_RS28940 da626323fcacad792e3b44db4dcb3451 138 Pfam PF01850 PIN domain 2 125 4.3E-13 T 06-07-2017 IPR002716 PIN domain BWK49_RS28940 da626323fcacad792e3b44db4dcb3451 138 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 1 132 12.019 T 06-07-2017 IPR022907 VapC family GO:0004540 BWK49_RS23560 a82732e90f27414cf7e43200a2285a88 887 SUPERFAMILY SSF49879 204 323 8.42E-22 T 06-07-2017 IPR008984 SMAD/FHA domain GO:0005515 BWK49_RS23560 a82732e90f27414cf7e43200a2285a88 887 Pfam PF01061 ABC-2 type transporter 617 831 2.3E-14 T 06-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 BWK49_RS23560 a82732e90f27414cf7e43200a2285a88 887 Gene3D G3DSA:2.60.200.20 8 99 5.7E-20 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 BWK49_RS23560 a82732e90f27414cf7e43200a2285a88 887 Pfam PF00005 ABC transporter 356 503 3.5E-33 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 BWK49_RS23560 a82732e90f27414cf7e43200a2285a88 887 SMART SM00382 365 549 9.1E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS23560 a82732e90f27414cf7e43200a2285a88 887 Pfam PF00498 FHA domain 26 89 3.8E-15 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 BWK49_RS23560 a82732e90f27414cf7e43200a2285a88 887 Pfam PF00498 FHA domain 254 316 7.9E-15 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 BWK49_RS23560 a82732e90f27414cf7e43200a2285a88 887 SUPERFAMILY SSF52540 336 566 1.33E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS23560 a82732e90f27414cf7e43200a2285a88 887 SUPERFAMILY SSF49879 11 117 9.18E-23 T 06-07-2017 IPR008984 SMAD/FHA domain GO:0005515 BWK49_RS23560 a82732e90f27414cf7e43200a2285a88 887 ProSitePatterns PS00211 ABC transporters family signature. 475 489 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 BWK49_RS23560 a82732e90f27414cf7e43200a2285a88 887 SMART SM00240 252 302 2.5E-10 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 BWK49_RS23560 a82732e90f27414cf7e43200a2285a88 887 SMART SM00240 25 75 8.3E-14 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 BWK49_RS23560 a82732e90f27414cf7e43200a2285a88 887 Gene3D G3DSA:3.40.50.300 332 561 3.3E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS23560 a82732e90f27414cf7e43200a2285a88 887 Gene3D G3DSA:2.60.200.20 187 330 4.4E-21 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 BWK49_RS05985 28ff4ee6eab05ce029919d8cb420dd14 225 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 67 2.0E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS05985 28ff4ee6eab05ce029919d8cb420dd14 225 Gene3D G3DSA:1.10.357.10 9 115 1.9E-22 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS05985 28ff4ee6eab05ce029919d8cb420dd14 225 Gene3D G3DSA:1.10.357.10 150 219 1.9E-22 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS05985 28ff4ee6eab05ce029919d8cb420dd14 225 SUPERFAMILY SSF46689 7 84 3.59E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS27505 e2b4119a63739ddbbbf7ef47316c2089 133 Pfam PF12680 SnoaL-like domain 22 113 2.1E-7 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain BWK49_RS27505 e2b4119a63739ddbbbf7ef47316c2089 133 Gene3D G3DSA:3.10.450.50 11 130 8.3E-19 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS27505 e2b4119a63739ddbbbf7ef47316c2089 133 SUPERFAMILY SSF54427 15 122 3.19E-20 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS15760 fd350362c51ed8ff0ccdf92ea134477d 305 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 146 268 4.2E-20 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain BWK49_RS15760 fd350362c51ed8ff0ccdf92ea134477d 305 Gene3D G3DSA:3.10.180.10 139 297 2.3E-50 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS15760 fd350362c51ed8ff0ccdf92ea134477d 305 Gene3D G3DSA:3.10.180.10 5 135 9.2E-30 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS15760 fd350362c51ed8ff0ccdf92ea134477d 305 SUPERFAMILY SSF54593 3 279 2.59E-35 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS15760 fd350362c51ed8ff0ccdf92ea134477d 305 TIGRFAM TIGR03213 23dbph12diox: 2,3-dihydroxybiphenyl 1,2-dioxygenase 5 295 1.8E-110 T 06-07-2017 IPR017626 2,3-dihydroxybiphenyl 1,2-dioxygenase GO:0005506|GO:0042178|GO:0051213|GO:0055114 BWK49_RS19115 badcbde21be632fc184697099a5dda15 148 SUPERFAMILY SSF55961 6 142 1.01E-11 T 06-07-2017 BWK49_RS00895 90357d64fc8903b7b7d9665a5b59c67e 146 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 27 111 3.5E-15 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 BWK49_RS00895 90357d64fc8903b7b7d9665a5b59c67e 146 Pfam PF04075 Domain of unknown function (DUF385) 25 111 2.9E-7 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 BWK49_RS06090 0d55403e08ea813952a714c32d137619 432 SUPERFAMILY SSF51556 8 36 1.7E-77 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS06090 0d55403e08ea813952a714c32d137619 432 SUPERFAMILY SSF51556 67 383 1.7E-77 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS06090 0d55403e08ea813952a714c32d137619 432 Gene3D G3DSA:3.20.20.140 8 390 1.1E-71 T 06-07-2017 BWK49_RS06090 0d55403e08ea813952a714c32d137619 432 Pfam PF04909 Amidohydrolase 86 374 8.0E-34 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 BWK49_RS28230 f1e5210f0bf6afbae5beddbb109aa39b 405 Pfam PF07730 Histidine kinase 190 254 1.7E-14 T 06-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 BWK49_RS14775 7a21b5591767f6bc5ffa5f2fbf3ffcd5 371 Pfam PF04909 Amidohydrolase 217 370 1.9E-14 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 BWK49_RS14775 7a21b5591767f6bc5ffa5f2fbf3ffcd5 371 Gene3D G3DSA:3.20.20.140 6 370 4.1E-114 T 06-07-2017 BWK49_RS14775 7a21b5591767f6bc5ffa5f2fbf3ffcd5 371 SUPERFAMILY SSF51556 16 173 1.87E-13 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS14775 7a21b5591767f6bc5ffa5f2fbf3ffcd5 371 SUPERFAMILY SSF51556 200 370 1.87E-13 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS08355 7ea09dafcfb2f9ef2e1d221d7a555834 228 Pfam PF11139 Sap, sulfolipid-1-addressing protein 7 225 4.5E-62 T 06-07-2017 IPR021315 Glycolipid exporter Gap/Sap BWK49_RS11240 ecb994021c0bdd0a0eb9654e2b1c4909 425 Pfam PF01266 FAD dependent oxidoreductase 14 399 1.7E-43 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 BWK49_RS11240 ecb994021c0bdd0a0eb9654e2b1c4909 425 Gene3D G3DSA:3.50.50.60 13 68 6.3E-42 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS11240 ecb994021c0bdd0a0eb9654e2b1c4909 425 Gene3D G3DSA:3.50.50.60 196 277 6.3E-42 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS11240 ecb994021c0bdd0a0eb9654e2b1c4909 425 Gene3D G3DSA:3.50.50.60 363 416 6.3E-42 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS11240 ecb994021c0bdd0a0eb9654e2b1c4909 425 Gene3D G3DSA:3.50.50.60 139 140 6.3E-42 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS11240 ecb994021c0bdd0a0eb9654e2b1c4909 425 SUPERFAMILY SSF51905 125 278 5.44E-37 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS11240 ecb994021c0bdd0a0eb9654e2b1c4909 425 SUPERFAMILY SSF51905 363 423 5.44E-37 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS11240 ecb994021c0bdd0a0eb9654e2b1c4909 425 SUPERFAMILY SSF51905 14 72 5.44E-37 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS06625 6bfe33642c306d8fd96d5c67d446790d 162 ProDom PD034580 PRECURSOR SIGNAL EXPORTED MB0899C RV0875C/MT0898 MLCB57.27C POSSIBLE 30 162 1.0E-65 T 06-07-2017 IPR024495 Protein of unknown function DUF2771 BWK49_RS06625 6bfe33642c306d8fd96d5c67d446790d 162 Pfam PF10969 Protein of unknown function (DUF2771) 6 159 1.9E-48 T 06-07-2017 IPR024495 Protein of unknown function DUF2771 BWK49_RS04240 f89793aa70eb01ac73ca065028453d5d 60 SUPERFAMILY SSF46955 1 58 6.59E-6 T 06-07-2017 IPR009061 Putative DNA-binding domain BWK49_RS13510 afcb06c780372293ee4bdda5bb833eba 550 Pfam PF00823 PPE family 8 164 7.3E-59 T 06-07-2017 IPR000030 PPE family BWK49_RS13510 afcb06c780372293ee4bdda5bb833eba 550 SUPERFAMILY SSF140459 5 177 5.23E-59 T 06-07-2017 BWK49_RS12110 56cd5713818ccc4c1aea9254ce1cd18c 401 Gene3D G3DSA:1.10.630.10 11 399 3.7E-102 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS12110 56cd5713818ccc4c1aea9254ce1cd18c 401 Pfam PF00067 Cytochrome P450 204 372 5.9E-18 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS12110 56cd5713818ccc4c1aea9254ce1cd18c 401 PRINTS PR00385 P450 superfamily signature 276 287 9.7E-7 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS12110 56cd5713818ccc4c1aea9254ce1cd18c 401 PRINTS PR00385 P450 superfamily signature 241 258 9.7E-7 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS12110 56cd5713818ccc4c1aea9254ce1cd18c 401 PRINTS PR00385 P450 superfamily signature 342 351 9.7E-7 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS12110 56cd5713818ccc4c1aea9254ce1cd18c 401 PRINTS PR00385 P450 superfamily signature 351 362 9.7E-7 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS12110 56cd5713818ccc4c1aea9254ce1cd18c 401 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 344 353 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 BWK49_RS12110 56cd5713818ccc4c1aea9254ce1cd18c 401 PRINTS PR00359 B-class P450 signature 190 212 4.2E-40 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS12110 56cd5713818ccc4c1aea9254ce1cd18c 401 PRINTS PR00359 B-class P450 signature 276 287 4.2E-40 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS12110 56cd5713818ccc4c1aea9254ce1cd18c 401 PRINTS PR00359 B-class P450 signature 150 165 4.2E-40 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS12110 56cd5713818ccc4c1aea9254ce1cd18c 401 PRINTS PR00359 B-class P450 signature 87 98 4.2E-40 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS12110 56cd5713818ccc4c1aea9254ce1cd18c 401 PRINTS PR00359 B-class P450 signature 321 336 4.2E-40 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS12110 56cd5713818ccc4c1aea9254ce1cd18c 401 PRINTS PR00359 B-class P450 signature 133 149 4.2E-40 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS12110 56cd5713818ccc4c1aea9254ce1cd18c 401 PRINTS PR00359 B-class P450 signature 293 320 4.2E-40 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS12110 56cd5713818ccc4c1aea9254ce1cd18c 401 PRINTS PR00359 B-class P450 signature 351 362 4.2E-40 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS12110 56cd5713818ccc4c1aea9254ce1cd18c 401 PRINTS PR00359 B-class P450 signature 342 351 4.2E-40 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS12110 56cd5713818ccc4c1aea9254ce1cd18c 401 SUPERFAMILY SSF48264 14 400 8.12E-84 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS20060 1422ce37a22ee70633d078e5823ed87e 194 Pfam PF08044 Domain of unknown function (DUF1707) 11 63 5.0E-19 T 06-07-2017 IPR012551 Protein of unknown function DUF1707 BWK49_RS28825 3b50d37f7191c83ced17840896bd9327 251 Pfam PF10935 Protein of unknown function (DUF2637) 27 143 8.9E-8 T 06-07-2017 IPR021235 Protein of unknown function DUF2637 BWK49_RS19965 53ad1d370ef2c33a63379a0206aea418 204 PIRSF PIRSF015617 4 204 5.1E-64 T 06-07-2017 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 BWK49_RS19965 53ad1d370ef2c33a63379a0206aea418 204 Gene3D G3DSA:3.40.50.300 9 204 3.6E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS19965 53ad1d370ef2c33a63379a0206aea418 204 TIGRFAM TIGR00708 cobA: cob(I)yrinic acid a,c-diamide adenosyltransferase 18 204 2.6E-78 T 06-07-2017 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 BWK49_RS19965 53ad1d370ef2c33a63379a0206aea418 204 SUPERFAMILY SSF52540 12 204 8.1E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS19965 53ad1d370ef2c33a63379a0206aea418 204 Pfam PF02572 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 23 204 6.5E-59 T 06-07-2017 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 BWK49_RS25730 83dfc7138a03eb41dbcb1d5c522be7c3 102 Pfam PF11662 Protein of unknown function (DUF3263) 21 92 9.3E-36 T 06-07-2017 IPR021678 Protein of unknown function DUF3263 BWK49_RS10270 441359a21f6835e35b01065b11e44b46 403 Pfam PF05982 Na+-dependent bicarbonate transporter superfamily 16 394 3.0E-109 T 06-07-2017 IPR010293 Na+-dependent bicarbonate transporter superfamily BWK49_RS21020 139b38c6a320c543bd2713b65876e4d1 172 SUPERFAMILY SSF50475 24 169 6.49E-21 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 BWK49_RS21020 139b38c6a320c543bd2713b65876e4d1 172 Gene3D G3DSA:2.30.110.10 34 171 1.6E-24 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 BWK49_RS21020 139b38c6a320c543bd2713b65876e4d1 172 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 26 104 5.2E-9 T 06-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 BWK49_RS09520 60532a3efa99d2c8c7a14d78b881a49b 286 SUPERFAMILY SSF51679 5 280 3.53E-46 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS09520 60532a3efa99d2c8c7a14d78b881a49b 286 Gene3D G3DSA:3.20.20.30 7 280 4.6E-47 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS09520 60532a3efa99d2c8c7a14d78b881a49b 286 Pfam PF00296 Luciferase-like monooxygenase 14 189 3.4E-35 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS18300 52d4911e7ae6b0ca74e3c0c68efa04e7 466 TIGRFAM TIGR02946 acyl_WS_DGAT: acyltransferase, WS/DGAT/MGAT 4 459 4.0E-152 T 06-07-2017 IPR014292 Acyltransferase, WS/DGAT/MGAT GO:0016746|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 BWK49_RS18300 52d4911e7ae6b0ca74e3c0c68efa04e7 466 SUPERFAMILY SSF52777 4 155 6.89E-9 T 06-07-2017 BWK49_RS18300 52d4911e7ae6b0ca74e3c0c68efa04e7 466 Pfam PF06974 Protein of unknown function (DUF1298) 306 455 1.7E-33 T 06-07-2017 IPR009721 O-acyltransferase WSD1, C-terminal GO:0004144 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 BWK49_RS18300 52d4911e7ae6b0ca74e3c0c68efa04e7 466 Pfam PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain 4 265 5.5E-83 T 06-07-2017 IPR004255 O-acyltransferase, WSD1, N-terminal GO:0004144|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 BWK49_RS17805 acc27c0c479d956ef9e3e002816eb12f 324 Pfam PF00487 Fatty acid desaturase 33 264 6.1E-28 T 06-07-2017 IPR005804 Fatty acid desaturase domain GO:0006629 BWK49_RS04200 1f94689ef470374e3f2c6cfe95cae8d2 299 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 17 273 1.5E-80 T 06-07-2017 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 BWK49_RS04200 1f94689ef470374e3f2c6cfe95cae8d2 299 Pfam PF04072 Leucine carboxyl methyltransferase 19 197 2.4E-62 T 06-07-2017 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 BWK49_RS04200 1f94689ef470374e3f2c6cfe95cae8d2 299 SUPERFAMILY SSF53335 15 284 3.65E-74 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS04200 1f94689ef470374e3f2c6cfe95cae8d2 299 Gene3D G3DSA:3.40.50.150 61 212 5.8E-16 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS14545 97bd478eb0ec7ac6dcef5dac60c731d9 155 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 6 148 5.0E-24 T 06-07-2017 IPR019587 Polyketide cyclase/dehydrase BWK49_RS14545 97bd478eb0ec7ac6dcef5dac60c731d9 155 SUPERFAMILY SSF55961 7 148 4.52E-21 T 06-07-2017 BWK49_RS14545 97bd478eb0ec7ac6dcef5dac60c731d9 155 Gene3D G3DSA:3.30.530.20 9 151 3.8E-16 T 06-07-2017 IPR023393 START-like domain BWK49_RS26390 d54942b680585a1675e82e57bb192717 222 Gene3D G3DSA:3.40.109.10 10 218 2.0E-47 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 BWK49_RS26390 d54942b680585a1675e82e57bb192717 222 TIGRFAM TIGR02476 BluB: 5,6-dimethylbenzimidazole synthase 9 209 7.6E-75 T 06-07-2017 IPR012825 5,6-dimethylbenzimidazole synthase BluB KEGG: 00740+1.13.11.79|MetaCyc: PWY-5508|MetaCyc: PWY-5523 BWK49_RS26390 d54942b680585a1675e82e57bb192717 222 SUPERFAMILY SSF55469 17 217 4.19E-48 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 BWK49_RS26390 d54942b680585a1675e82e57bb192717 222 Pfam PF00881 Nitroreductase family 21 185 1.6E-28 T 06-07-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 BWK49_RS06640 9161722c9e98498b424176020730b8de 151 Gene3D G3DSA:3.30.530.20 5 150 1.3E-26 T 06-07-2017 IPR023393 START-like domain BWK49_RS06640 9161722c9e98498b424176020730b8de 151 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 7 149 2.8E-18 T 06-07-2017 IPR019587 Polyketide cyclase/dehydrase BWK49_RS06640 9161722c9e98498b424176020730b8de 151 SUPERFAMILY SSF55961 7 150 3.44E-23 T 06-07-2017 BWK49_RS22820 1213d33ff48ad8a2791ab375d23135a2 465 Pfam PF02720 Domain of unknown function (DUF222) 40 364 1.2E-94 T 06-07-2017 IPR003870 Domain of unknown function DUF222 BWK49_RS22820 1213d33ff48ad8a2791ab375d23135a2 465 ProDom PD008243 RV1792C/MT1741/MB1728C RV1945/MT1995 MB1980 MB0098C RV3466/MT3572 VERY RV1128C/MT1160 RV1148C/MT1183 MB1159C RV0095C 23 95 6.0E-18 T 06-07-2017 BWK49_RS22820 1213d33ff48ad8a2791ab375d23135a2 465 SMART SM00507 355 407 6.1E-5 T 06-07-2017 IPR003615 HNH nuclease BWK49_RS01820 d73953b9a270b9a6fb7c94904b8df3de 359 SMART SM01130 16 310 4.5E-62 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 BWK49_RS01820 d73953b9a270b9a6fb7c94904b8df3de 359 PRINTS PR00146 Dihydrodipicolinate synthase signature 53 74 1.6E-11 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 BWK49_RS01820 d73953b9a270b9a6fb7c94904b8df3de 359 PRINTS PR00146 Dihydrodipicolinate synthase signature 89 107 1.6E-11 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 BWK49_RS01820 d73953b9a270b9a6fb7c94904b8df3de 359 PRINTS PR00146 Dihydrodipicolinate synthase signature 121 137 1.6E-11 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 BWK49_RS01820 d73953b9a270b9a6fb7c94904b8df3de 359 PRINTS PR00146 Dihydrodipicolinate synthase signature 147 164 1.6E-11 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 BWK49_RS01820 d73953b9a270b9a6fb7c94904b8df3de 359 Gene3D G3DSA:3.20.20.70 11 320 4.0E-70 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 BWK49_RS01820 d73953b9a270b9a6fb7c94904b8df3de 359 Pfam PF00701 Dihydrodipicolinate synthetase family 31 300 3.5E-43 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 BWK49_RS01820 d73953b9a270b9a6fb7c94904b8df3de 359 SUPERFAMILY SSF51569 13 309 2.93E-65 T 06-07-2017 BWK49_RS06355 fae53c5f8f9163e04f4bbe32b219398e 372 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 13 291 1.9E-55 T 06-07-2017 IPR005693 Virulence factor Mce protein BWK49_RS06355 fae53c5f8f9163e04f4bbe32b219398e 372 Pfam PF02470 MlaD protein 40 112 8.0E-14 T 06-07-2017 IPR003399 Mce/MlaD BWK49_RS06355 fae53c5f8f9163e04f4bbe32b219398e 372 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 153 307 1.5E-8 T 06-07-2017 IPR024516 Mammalian cell entry, C-terminal BWK49_RS06355 fae53c5f8f9163e04f4bbe32b219398e 372 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 91 107 2.1E-7 T 06-07-2017 IPR005693 Virulence factor Mce protein BWK49_RS06355 fae53c5f8f9163e04f4bbe32b219398e 372 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 178 196 2.1E-7 T 06-07-2017 IPR005693 Virulence factor Mce protein BWK49_RS06355 fae53c5f8f9163e04f4bbe32b219398e 372 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 129 153 2.1E-7 T 06-07-2017 IPR005693 Virulence factor Mce protein BWK49_RS06355 fae53c5f8f9163e04f4bbe32b219398e 372 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 332 350 2.1E-7 T 06-07-2017 IPR005693 Virulence factor Mce protein BWK49_RS26360 fa9f6d9d7f46ad405b2678e5765e5a5f 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 33 79 1.4E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS26360 fa9f6d9d7f46ad405b2678e5765e5a5f 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 46 1.1E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS26360 fa9f6d9d7f46ad405b2678e5765e5a5f 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 54 77 1.1E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS26360 fa9f6d9d7f46ad405b2678e5765e5a5f 210 Gene3D G3DSA:1.10.357.10 15 207 1.2E-30 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS26360 fa9f6d9d7f46ad405b2678e5765e5a5f 210 SUPERFAMILY SSF46689 20 104 3.44E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS02800 b38b0ec7ce14e49728da00e51d7f72c8 272 Pfam PF00293 NUDIX domain 99 197 2.5E-10 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 BWK49_RS02800 b38b0ec7ce14e49728da00e51d7f72c8 272 SUPERFAMILY SSF55811 96 236 1.1E-24 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 BWK49_RS02800 b38b0ec7ce14e49728da00e51d7f72c8 272 Gene3D G3DSA:3.90.79.10 73 244 1.1E-28 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 BWK49_RS18680 c69494ed02ca721c730f5916ce66fde6 355 Pfam PF13515 Fusaric acid resistance protein-like 45 165 2.9E-14 T 06-07-2017 BWK49_RS23805 7a542fcbe8ada3ea9e0badc1e377d9bd 173 Gene3D G3DSA:1.20.120.520 5 136 1.5E-10 T 06-07-2017 BWK49_RS23805 7a542fcbe8ada3ea9e0badc1e377d9bd 173 Pfam PF01814 Hemerythrin HHE cation binding domain 3 115 4.2E-14 T 06-07-2017 IPR012312 Haemerythrin-like Reactome: R-HSA-390471 BWK49_RS18130 54ef86600d1c69c2abecbdd4b6309433 177 Gene3D G3DSA:3.30.240.20 95 161 2.5E-16 T 06-07-2017 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain BWK49_RS18130 54ef86600d1c69c2abecbdd4b6309433 177 Pfam PF04239 Protein of unknown function (DUF421) 98 162 1.6E-12 T 06-07-2017 IPR007353 Protein of unknown function DUF421 BWK49_RS16120 3b4af0ab2b50696528e47e53b8e658be 119 SUPERFAMILY SSF46785 10 91 5.96E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS16120 3b4af0ab2b50696528e47e53b8e658be 119 Gene3D G3DSA:1.10.10.10 9 94 2.1E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS16120 3b4af0ab2b50696528e47e53b8e658be 119 SMART SM00418 13 91 4.1E-29 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 BWK49_RS16120 3b4af0ab2b50696528e47e53b8e658be 119 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 15 30 3.2E-9 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 BWK49_RS16120 3b4af0ab2b50696528e47e53b8e658be 119 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 62 77 3.2E-9 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 BWK49_RS16120 3b4af0ab2b50696528e47e53b8e658be 119 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 47 62 3.2E-9 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 BWK49_RS16120 3b4af0ab2b50696528e47e53b8e658be 119 Pfam PF01022 Bacterial regulatory protein, arsR family 20 65 1.8E-16 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 BWK49_RS15355 5221795b089b8466e7179fda3a7ffa0c 283 SMART SM00342 175 257 3.1E-12 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 BWK49_RS15355 5221795b089b8466e7179fda3a7ffa0c 283 Gene3D G3DSA:1.10.10.60 213 261 3.4E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS15355 5221795b089b8466e7179fda3a7ffa0c 283 Gene3D G3DSA:1.10.10.60 159 212 2.0E-7 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS15355 5221795b089b8466e7179fda3a7ffa0c 283 Pfam PF12833 Helix-turn-helix domain 183 259 6.9E-19 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 BWK49_RS15355 5221795b089b8466e7179fda3a7ffa0c 283 SUPERFAMILY SSF46689 211 264 5.38E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS20900 1493cd82d3c8303d2c004c9233bedd8c 268 Pfam PF10370 Domain of unknown function (DUF2437) 1 57 4.8E-14 T 06-07-2017 IPR018833 Domain of unknown function DUF2437 BWK49_RS20900 1493cd82d3c8303d2c004c9233bedd8c 268 SUPERFAMILY SSF56529 61 263 1.57E-76 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 BWK49_RS20900 1493cd82d3c8303d2c004c9233bedd8c 268 Gene3D G3DSA:3.90.850.10 53 264 1.7E-87 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 BWK49_RS20900 1493cd82d3c8303d2c004c9233bedd8c 268 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 62 262 4.1E-70 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 BWK49_RS17540 51d6d82244f338d9dea47525171a2b6e 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 44 55 1.2E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS17540 51d6d82244f338d9dea47525171a2b6e 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 1.2E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS17540 51d6d82244f338d9dea47525171a2b6e 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 1.2E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS17540 51d6d82244f338d9dea47525171a2b6e 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 1.2E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS17540 51d6d82244f338d9dea47525171a2b6e 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 1.2E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS17540 51d6d82244f338d9dea47525171a2b6e 267 Pfam PF00106 short chain dehydrogenase 11 198 1.1E-45 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS17540 51d6d82244f338d9dea47525171a2b6e 267 Gene3D G3DSA:3.40.50.720 11 250 1.8E-58 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS17540 51d6d82244f338d9dea47525171a2b6e 267 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS17540 51d6d82244f338d9dea47525171a2b6e 267 PIRSF PIRSF000126 1 265 8.3E-74 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS17540 51d6d82244f338d9dea47525171a2b6e 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 44 55 2.9E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS17540 51d6d82244f338d9dea47525171a2b6e 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 2.9E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS17540 51d6d82244f338d9dea47525171a2b6e 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 2.9E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS17540 51d6d82244f338d9dea47525171a2b6e 267 SUPERFAMILY SSF51735 11 245 2.44E-57 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS22090 7266fab0b60236ff823046f05c668852 290 SUPERFAMILY SSF51735 132 274 7.2E-50 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS22090 7266fab0b60236ff823046f05c668852 290 SUPERFAMILY SSF51735 2 105 7.2E-50 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS22090 7266fab0b60236ff823046f05c668852 290 Gene3D G3DSA:3.40.50.720 1 274 1.2E-60 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS22090 7266fab0b60236ff823046f05c668852 290 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 91 102 7.8E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS22090 7266fab0b60236ff823046f05c668852 290 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 170 178 7.8E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS22090 7266fab0b60236ff823046f05c668852 290 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 199 218 7.8E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS22090 7266fab0b60236ff823046f05c668852 290 Pfam PF00106 short chain dehydrogenase 9 230 3.7E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS22090 7266fab0b60236ff823046f05c668852 290 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.4E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS22090 7266fab0b60236ff823046f05c668852 290 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 199 218 1.4E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS22090 7266fab0b60236ff823046f05c668852 290 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 220 237 1.4E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS22090 7266fab0b60236ff823046f05c668852 290 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 180 1.4E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS22090 7266fab0b60236ff823046f05c668852 290 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 91 102 1.4E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS23070 79608fbbf783560928c30f130b4d2d0b 304 SUPERFAMILY SSF53335 15 295 1.96E-73 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS23070 79608fbbf783560928c30f130b4d2d0b 304 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 17 275 2.8E-75 T 06-07-2017 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 BWK49_RS23070 79608fbbf783560928c30f130b4d2d0b 304 Gene3D G3DSA:3.40.50.150 80 216 4.8E-12 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS23070 79608fbbf783560928c30f130b4d2d0b 304 Pfam PF04072 Leucine carboxyl methyltransferase 19 202 6.8E-65 T 06-07-2017 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 BWK49_RS12280 91a9846944de65aa648e9653f3f30c87 150 SUPERFAMILY SSF54593 8 139 1.02E-22 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS12280 91a9846944de65aa648e9653f3f30c87 150 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 125 5.1E-10 T 06-07-2017 BWK49_RS12280 91a9846944de65aa648e9653f3f30c87 150 Gene3D G3DSA:3.10.180.10 8 139 2.5E-22 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS12280 91a9846944de65aa648e9653f3f30c87 150 ProSitePatterns PS00934 Glyoxalase I signature 1. 10 31 - T 06-07-2017 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 BWK49_RS16100 14f6b64c66b815d16ae9486a512310e0 111 Pfam PF13453 Transcription factor zinc-finger 10 48 5.5E-16 T 06-07-2017 IPR027392 Transcription factor zinc-finger BWK49_RS21520 f17bf12e5550087f5033e02b04dc0d3f 275 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 272 8.2E-50 T 06-07-2017 BWK49_RS21520 f17bf12e5550087f5033e02b04dc0d3f 275 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 99 110 4.4E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS21520 f17bf12e5550087f5033e02b04dc0d3f 275 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 161 4.4E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS21520 f17bf12e5550087f5033e02b04dc0d3f 275 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 173 192 4.4E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS21520 f17bf12e5550087f5033e02b04dc0d3f 275 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 160 188 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS21520 f17bf12e5550087f5033e02b04dc0d3f 275 Gene3D G3DSA:3.40.50.720 4 272 4.2E-75 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS21520 f17bf12e5550087f5033e02b04dc0d3f 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 194 211 1.4E-33 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS21520 f17bf12e5550087f5033e02b04dc0d3f 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 1.4E-33 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS21520 f17bf12e5550087f5033e02b04dc0d3f 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 192 1.4E-33 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS21520 f17bf12e5550087f5033e02b04dc0d3f 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 236 256 1.4E-33 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS21520 f17bf12e5550087f5033e02b04dc0d3f 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 99 110 1.4E-33 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS21520 f17bf12e5550087f5033e02b04dc0d3f 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 163 1.4E-33 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS21520 f17bf12e5550087f5033e02b04dc0d3f 275 TIGRFAM TIGR03971 SDR_subfam_1: SDR family mycofactocin-dependent oxidoreductase 8 273 1.8E-107 T 06-07-2017 IPR023985 Mycofactocin-dependent oxidoreductase BWK49_RS21520 f17bf12e5550087f5033e02b04dc0d3f 275 SUPERFAMILY SSF51735 5 274 3.69E-69 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS26070 957f880358f1f4e641dabbc900f4b68b 179 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 179 25.491 T 06-07-2017 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|Reactome: R-HSA-500753 BWK49_RS26070 957f880358f1f4e641dabbc900f4b68b 179 SUPERFAMILY SSF53271 6 175 4.59E-35 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like BWK49_RS26070 957f880358f1f4e641dabbc900f4b68b 179 Pfam PF00156 Phosphoribosyl transferase domain 45 157 1.1E-10 T 06-07-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 BWK49_RS26070 957f880358f1f4e641dabbc900f4b68b 179 Gene3D G3DSA:3.40.50.2020 5 176 1.6E-52 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like BWK49_RS26070 957f880358f1f4e641dabbc900f4b68b 179 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 17 174 2.1E-36 T 06-07-2017 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|Reactome: R-HSA-500753 BWK49_RS21185 a8fb20388d249d1984fc0acddbcc148f 71 Pfam PF11160 Protein of unknown function (DUF2945) 9 68 6.6E-25 T 06-07-2017 IPR021331 Protein of unknown function DUF2945 BWK49_RS00440 a301b2b83837f94143c76433bf9d6af3 185 Pfam PF13577 SnoaL-like domain 15 137 1.3E-20 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain BWK49_RS00440 a301b2b83837f94143c76433bf9d6af3 185 SUPERFAMILY SSF54427 10 176 4.04E-39 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS00440 a301b2b83837f94143c76433bf9d6af3 185 Gene3D G3DSA:3.10.450.50 17 147 2.8E-30 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS25490 22dd74af59e1f9d85cfe6cd57719ff27 471 Pfam PF01381 Helix-turn-helix 10 63 1.5E-12 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 BWK49_RS25490 22dd74af59e1f9d85cfe6cd57719ff27 471 Pfam PF09856 Predicted transcriptional regulator (DUF2083) 311 466 1.8E-69 T 06-07-2017 IPR018653 Domain of unknown function DUF2083,transcriptional regulator BWK49_RS25490 22dd74af59e1f9d85cfe6cd57719ff27 471 Pfam PF06114 Domain of unknown function (DUF955) 188 310 2.5E-25 T 06-07-2017 IPR010359 HTH domain, IrrE-type BWK49_RS25490 22dd74af59e1f9d85cfe6cd57719ff27 471 PIRSF PIRSF019251 1 471 3.8E-199 T 06-07-2017 IPR026281 HTH-type transcriptional regulator RamB GO:0006355 BWK49_RS25490 22dd74af59e1f9d85cfe6cd57719ff27 471 Gene3D G3DSA:1.10.260.40 5 74 1.4E-17 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 BWK49_RS25490 22dd74af59e1f9d85cfe6cd57719ff27 471 SUPERFAMILY SSF47413 4 68 1.02E-14 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 BWK49_RS25490 22dd74af59e1f9d85cfe6cd57719ff27 471 SMART SM00530 9 64 8.4E-14 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 BWK49_RS01275 ebb69734995cb4c197ae2c5041cab094 265 Pfam PF00005 ABC transporter 50 180 8.7E-18 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 BWK49_RS01275 ebb69734995cb4c197ae2c5041cab094 265 SUPERFAMILY SSF52540 48 244 6.93E-39 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS01275 ebb69734995cb4c197ae2c5041cab094 265 Gene3D G3DSA:3.40.50.300 47 247 3.8E-37 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS01275 ebb69734995cb4c197ae2c5041cab094 265 SMART SM00382 59 248 2.4E-5 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS15350 c1f58968eed78ec3c474cdfdc4f6f69d 274 SUPERFAMILY SSF53335 8 270 9.64E-66 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS15350 c1f58968eed78ec3c474cdfdc4f6f69d 274 Pfam PF04072 Leucine carboxyl methyltransferase 13 179 4.4E-50 T 06-07-2017 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 BWK49_RS15350 c1f58968eed78ec3c474cdfdc4f6f69d 274 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 10 250 2.4E-74 T 06-07-2017 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 BWK49_RS15350 c1f58968eed78ec3c474cdfdc4f6f69d 274 Gene3D G3DSA:3.40.50.150 16 213 5.6E-20 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS12545 46ae74149fa567f821139238944af7e8 245 Pfam PF02591 C4-type zinc ribbon domain 203 237 1.9E-11 T 06-07-2017 IPR003743 C4-type zinc ribbon domain BWK49_RS27575 54786850cb9dd1e973e134d0fd4b6175 171 Gene3D G3DSA:3.30.530.20 10 168 3.0E-16 T 06-07-2017 IPR023393 START-like domain BWK49_RS27575 54786850cb9dd1e973e134d0fd4b6175 171 SUPERFAMILY SSF55961 11 169 1.22E-21 T 06-07-2017 BWK49_RS27575 54786850cb9dd1e973e134d0fd4b6175 171 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 13 166 2.1E-14 T 06-07-2017 IPR019587 Polyketide cyclase/dehydrase BWK49_RS01155 8dbb2b5f10229792b4f69699888a4e8f 347 SUPERFAMILY SSF53474 44 327 5.53E-38 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS01155 8dbb2b5f10229792b4f69699888a4e8f 347 Gene3D G3DSA:3.40.50.1820 46 327 4.9E-131 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS01155 8dbb2b5f10229792b4f69699888a4e8f 347 Pfam PF00756 Putative esterase 58 321 3.6E-72 T 06-07-2017 IPR000801 Putative esterase Reactome: R-HSA-156590 BWK49_RS12520 b2f03f2c1be443deea27e681bf637390 275 Pfam PF02104 SURF1 family 23 226 1.2E-21 T 06-07-2017 IPR002994 Surfeit locus 1/Shy1 GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 BWK49_RS17835 645ae0d808e53ce46c1afd4671be21ac 138 Gene3D G3DSA:2.30.110.10 56 112 4.7E-4 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 BWK49_RS17835 645ae0d808e53ce46c1afd4671be21ac 138 Pfam PF04075 Domain of unknown function (DUF385) 12 100 4.3E-13 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 BWK49_RS17835 645ae0d808e53ce46c1afd4671be21ac 138 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 13 135 1.8E-35 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 BWK49_RS17835 645ae0d808e53ce46c1afd4671be21ac 138 SUPERFAMILY SSF50475 31 110 7.53E-6 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 BWK49_RS24500 36bfd86ebfa7989d434ab101286cd732 500 Pfam PF03055 Retinal pigment epithelial membrane protein 19 498 3.5E-99 T 06-07-2017 IPR004294 Carotenoid oxygenase GO:0016702|GO:0055114 BWK49_RS10280 4b06578f4b689ae4e38dda1a0ef8a2a3 450 SUPERFAMILY SSF56322 27 446 1.7E-93 T 06-07-2017 IPR005801 ADC synthase GO:0009058 BWK49_RS10280 4b06578f4b689ae4e38dda1a0ef8a2a3 450 Gene3D G3DSA:3.60.120.10 82 446 3.8E-80 T 06-07-2017 IPR005801 ADC synthase GO:0009058 BWK49_RS10280 4b06578f4b689ae4e38dda1a0ef8a2a3 450 Pfam PF00425 chorismate binding enzyme 185 438 3.4E-64 T 06-07-2017 IPR015890 Chorismate-utilising enzyme, C-terminal BWK49_RS10280 4b06578f4b689ae4e38dda1a0ef8a2a3 450 PRINTS PR00095 Anthranilate synthase component I signature 380 394 1.0E-5 T 06-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 BWK49_RS10280 4b06578f4b689ae4e38dda1a0ef8a2a3 450 PRINTS PR00095 Anthranilate synthase component I signature 395 409 1.0E-5 T 06-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 BWK49_RS10280 4b06578f4b689ae4e38dda1a0ef8a2a3 450 PRINTS PR00095 Anthranilate synthase component I signature 286 299 1.0E-5 T 06-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 BWK49_RS10280 4b06578f4b689ae4e38dda1a0ef8a2a3 450 TIGRFAM TIGR03494 salicyl_syn: salicylate synthase 29 448 5.2E-196 T 06-07-2017 IPR019996 Salicylate synthase GO:0008909|GO:0016833 KEGG: 00130+5.4.4.2|KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6120|MetaCyc: PWY-6406|MetaCyc: PWY-6627|MetaCyc: PWY-7626 BWK49_RS07945 79f5f2ba038f7af40d6ab57b2d544ac4 107 SUPERFAMILY SSF54909 1 97 1.7E-25 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel BWK49_RS07945 79f5f2ba038f7af40d6ab57b2d544ac4 107 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 76 3.7E-17 T 06-07-2017 IPR007138 Antibiotic biosynthesis monooxygenase domain BWK49_RS07945 79f5f2ba038f7af40d6ab57b2d544ac4 107 Gene3D G3DSA:3.30.70.900 1 90 3.7E-23 T 06-07-2017 BWK49_RS06340 807e466029abb0d83fc7575b53cda0a5 282 Pfam PF02405 Permease MlaE 65 268 3.3E-54 T 06-07-2017 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 BWK49_RS15490 cccd570a2bf77171d9cff5d0b529230a 232 Gene3D G3DSA:1.10.357.10 10 216 3.5E-23 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS15490 cccd570a2bf77171d9cff5d0b529230a 232 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 71 2.1E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS15490 cccd570a2bf77171d9cff5d0b529230a 232 SUPERFAMILY SSF46689 13 92 2.77E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS12215 edd13b0efb5acde1ad509d9f24deefa8 238 SUPERFAMILY SSF53800 4 232 9.05E-32 T 06-07-2017 BWK49_RS12215 edd13b0efb5acde1ad509d9f24deefa8 238 Gene3D G3DSA:3.40.50.1400 122 234 2.2E-19 T 06-07-2017 BWK49_RS12215 edd13b0efb5acde1ad509d9f24deefa8 238 Gene3D G3DSA:3.40.50.1400 3 113 3.1E-25 T 06-07-2017 BWK49_RS12215 edd13b0efb5acde1ad509d9f24deefa8 238 Pfam PF01903 CbiX 130 225 4.6E-10 T 06-07-2017 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 BWK49_RS12215 edd13b0efb5acde1ad509d9f24deefa8 238 Pfam PF01903 CbiX 9 108 3.2E-18 T 06-07-2017 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 BWK49_RS08925 3c8a1bbf97ea026c28691043f6485fec 219 Gene3D G3DSA:3.90.870.10 10 209 5.0E-64 T 06-07-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain BWK49_RS08925 3c8a1bbf97ea026c28691043f6485fec 219 SUPERFAMILY SSF55821 4 208 8.24E-56 T 06-07-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain BWK49_RS08925 3c8a1bbf97ea026c28691043f6485fec 219 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 7 208 9.8E-66 T 06-07-2017 IPR006070 YrdC-like domain GO:0003725 BWK49_RS08925 3c8a1bbf97ea026c28691043f6485fec 219 Pfam PF01300 Telomere recombination 23 197 3.7E-44 T 06-07-2017 IPR006070 YrdC-like domain GO:0003725 BWK49_RS17205 c5b9c0f8ad1fc4728cbd9933b9c24b22 443 ProSitePatterns PS00452 Guanylate cyclase signature. 355 378 - T 06-07-2017 IPR018297 Adenylyl cyclase class-4/guanylyl cyclase, conserved site GO:0009190|GO:0016849|GO:0035556 BWK49_RS17205 c5b9c0f8ad1fc4728cbd9933b9c24b22 443 SUPERFAMILY SSF55073 240 422 3.3E-62 T 06-07-2017 IPR029787 Nucleotide cyclase BWK49_RS17205 c5b9c0f8ad1fc4728cbd9933b9c24b22 443 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 244 422 1.0E-57 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 BWK49_RS17205 c5b9c0f8ad1fc4728cbd9933b9c24b22 443 Gene3D G3DSA:3.30.70.1230 239 427 4.7E-69 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 BWK49_RS17205 c5b9c0f8ad1fc4728cbd9933b9c24b22 443 SMART SM00044 214 412 2.6E-84 T 06-07-2017 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 BWK49_RS08265 9d1b4108fc6431cdf1171813f6cd95a4 244 Pfam PF02665 Nitrate reductase gamma subunit 4 225 5.2E-84 T 06-07-2017 IPR023234 NarG-like domain BWK49_RS08265 9d1b4108fc6431cdf1171813f6cd95a4 244 Gene3D G3DSA:1.20.950.20 4 217 2.5E-71 T 06-07-2017 BWK49_RS08265 9d1b4108fc6431cdf1171813f6cd95a4 244 SUPERFAMILY SSF103501 3 225 2.22E-64 T 06-07-2017 IPR023234 NarG-like domain BWK49_RS08265 9d1b4108fc6431cdf1171813f6cd95a4 244 TIGRFAM TIGR00351 narI: respiratory nitrate reductase, gamma subunit 2 225 1.7E-63 T 06-07-2017 IPR003816 Nitrate reductase, gamma subunit GO:0008940|GO:0009325|GO:0055114 KEGG: 00910+1.7.99.4 BWK49_RS07670 9843d7d3dff2c0867ac761295b958c49 139 ProDom PD076648 LIPOPROTEIN LPQV PALMITATE MEMBRANE PRECURSOR SIGNAL 18 120 4.0E-35 T 06-07-2017 IPR020377 Uncharacterised protein family LpqV BWK49_RS21010 b632cda0f50098bbe80b010387f9178e 973 Pfam PF03176 MMPL family 600 934 1.3E-98 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 BWK49_RS21010 b632cda0f50098bbe80b010387f9178e 973 Pfam PF03176 MMPL family 51 378 2.2E-107 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 BWK49_RS21010 b632cda0f50098bbe80b010387f9178e 973 SUPERFAMILY SSF82866 152 347 1.96E-27 T 06-07-2017 BWK49_RS21010 b632cda0f50098bbe80b010387f9178e 973 TIGRFAM TIGR00833 actII: transport protein 17 926 2.1E-290 T 06-07-2017 IPR004707 Membrane transport protein MmpL family GO:0016021 BWK49_RS21010 b632cda0f50098bbe80b010387f9178e 973 Gene3D G3DSA:1.20.1640.10 153 350 7.8E-27 T 06-07-2017 BWK49_RS21010 b632cda0f50098bbe80b010387f9178e 973 Gene3D G3DSA:1.20.1640.10 726 929 4.5E-24 T 06-07-2017 BWK49_RS21010 b632cda0f50098bbe80b010387f9178e 973 SUPERFAMILY SSF82866 717 926 7.72E-32 T 06-07-2017 BWK49_RS09020 fa07d21b4e33874061f9374fa968a464 378 SUPERFAMILY SSF140459 2 173 3.14E-65 T 06-07-2017 BWK49_RS09020 fa07d21b4e33874061f9374fa968a464 378 Pfam PF00823 PPE family 5 159 4.5E-63 T 06-07-2017 IPR000030 PPE family BWK49_RS09020 fa07d21b4e33874061f9374fa968a464 378 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 294 373 6.7E-18 T 06-07-2017 IPR022171 PPE family, C-terminal BWK49_RS24850 3c43c81e7dd889063eb8bb68175807d9 137 Pfam PF05305 Protein of unknown function (DUF732) 16 128 2.0E-22 T 06-07-2017 IPR007969 Domain of unknown function DUF732 BWK49_RS23320 7d2b407f69d7bf2b88e9ab3a14504879 584 SUPERFAMILY SSF54373 263 355 3.14E-8 T 06-07-2017 BWK49_RS23320 7d2b407f69d7bf2b88e9ab3a14504879 584 SUPERFAMILY SSF51905 33 305 2.22E-38 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS23320 7d2b407f69d7bf2b88e9ab3a14504879 584 SUPERFAMILY SSF51905 348 406 2.22E-38 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS23320 7d2b407f69d7bf2b88e9ab3a14504879 584 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 48 58 2.2E-34 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 BWK49_RS23320 7d2b407f69d7bf2b88e9ab3a14504879 584 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 379 391 2.2E-34 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 BWK49_RS23320 7d2b407f69d7bf2b88e9ab3a14504879 584 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 349 355 2.2E-34 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 BWK49_RS23320 7d2b407f69d7bf2b88e9ab3a14504879 584 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 35 47 2.2E-34 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 BWK49_RS23320 7d2b407f69d7bf2b88e9ab3a14504879 584 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 64 76 2.2E-34 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 BWK49_RS23320 7d2b407f69d7bf2b88e9ab3a14504879 584 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 110 122 2.2E-34 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 BWK49_RS23320 7d2b407f69d7bf2b88e9ab3a14504879 584 Pfam PF01266 FAD dependent oxidoreductase 36 384 1.9E-46 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 BWK49_RS23320 7d2b407f69d7bf2b88e9ab3a14504879 584 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 413 535 5.9E-26 T 06-07-2017 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 BWK49_RS23320 7d2b407f69d7bf2b88e9ab3a14504879 584 ProSitePatterns PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2. 384 394 - T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 BWK49_RS23320 7d2b407f69d7bf2b88e9ab3a14504879 584 Gene3D G3DSA:3.50.50.60 33 274 1.4E-45 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS23320 7d2b407f69d7bf2b88e9ab3a14504879 584 ProSitePatterns PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1. 40 57 - T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 BWK49_RS19065 4f8dc0edf2b6598acfe4e06a6f832224 131 Pfam PF01740 STAS domain 28 124 1.2E-13 T 06-07-2017 IPR002645 STAS domain BWK49_RS19065 4f8dc0edf2b6598acfe4e06a6f832224 131 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 16 122 1.1E-29 T 06-07-2017 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 BWK49_RS19065 4f8dc0edf2b6598acfe4e06a6f832224 131 SUPERFAMILY SSF52091 23 128 6.47E-18 T 06-07-2017 IPR002645 STAS domain BWK49_RS19065 4f8dc0edf2b6598acfe4e06a6f832224 131 Gene3D G3DSA:3.30.750.24 22 128 5.8E-17 T 06-07-2017 IPR002645 STAS domain BWK49_RS16910 df98ba7a4d90ad104dbbdc3ec7e02fcb 342 Pfam PF02720 Domain of unknown function (DUF222) 22 306 1.5E-62 T 06-07-2017 IPR003870 Domain of unknown function DUF222 BWK49_RS05095 558350549761f2c544fddcadbc8dd21b 977 SUPERFAMILY SSF82866 727 930 3.27E-27 T 06-07-2017 BWK49_RS05095 558350549761f2c544fddcadbc8dd21b 977 Pfam PF03176 MMPL family 606 938 1.1E-104 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 BWK49_RS05095 558350549761f2c544fddcadbc8dd21b 977 Pfam PF03176 MMPL family 54 383 2.3E-115 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 BWK49_RS05095 558350549761f2c544fddcadbc8dd21b 977 TIGRFAM TIGR00833 actII: transport protein 22 930 0.0 T 06-07-2017 IPR004707 Membrane transport protein MmpL family GO:0016021 BWK49_RS05095 558350549761f2c544fddcadbc8dd21b 977 Gene3D G3DSA:1.20.1640.10 154 351 1.7E-26 T 06-07-2017 BWK49_RS05095 558350549761f2c544fddcadbc8dd21b 977 Gene3D G3DSA:1.20.1640.10 730 932 1.1E-22 T 06-07-2017 BWK49_RS05095 558350549761f2c544fddcadbc8dd21b 977 SUPERFAMILY SSF82866 135 351 3.92E-26 T 06-07-2017 BWK49_RS05395 6721d28c78b7ab38122d2c92c6ba1532 375 SUPERFAMILY SSF56349 118 259 2.35E-16 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 BWK49_RS05395 6721d28c78b7ab38122d2c92c6ba1532 375 Gene3D G3DSA:1.10.150.130 111 197 2.8E-5 T 06-07-2017 IPR023109 Integrase/recombinase, N-terminal BWK49_RS11630 0f23a7129fedeef1b2ede801aad8a6f8 446 SUPERFAMILY SSF53850 42 440 7.76E-57 T 06-07-2017 BWK49_RS11630 0f23a7129fedeef1b2ede801aad8a6f8 446 Pfam PF01547 Bacterial extracellular solute-binding protein 51 356 4.3E-40 T 06-07-2017 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 BWK49_RS11630 0f23a7129fedeef1b2ede801aad8a6f8 446 Gene3D G3DSA:3.40.190.10 41 163 8.1E-23 T 06-07-2017 BWK49_RS11630 0f23a7129fedeef1b2ede801aad8a6f8 446 Gene3D G3DSA:3.40.190.10 164 372 3.2E-34 T 06-07-2017 BWK49_RS08600 4a8a60e163d5f85f3356e8a213d27929 297 Pfam PF13338 Transcriptional regulator, AbiEi antitoxin 27 95 1.2E-7 T 06-07-2017 IPR025159 Transcriptional regulator, AbiEi antitoxin BWK49_RS08600 4a8a60e163d5f85f3356e8a213d27929 297 SUPERFAMILY SSF52980 178 290 4.08E-8 T 06-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 BWK49_RS26995 1819595346e821791aeb062879ec4941 299 Pfam PF07859 alpha/beta hydrolase fold 73 270 9.1E-60 T 06-07-2017 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 BWK49_RS26995 1819595346e821791aeb062879ec4941 299 Gene3D G3DSA:3.40.50.1820 25 295 1.5E-76 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS26995 1819595346e821791aeb062879ec4941 299 SUPERFAMILY SSF53474 34 295 5.74E-61 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS21320 74069ceed58104e61c5d552f42b3d7de 517 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 27 233 5.4E-18 T 06-07-2017 BWK49_RS21320 74069ceed58104e61c5d552f42b3d7de 517 SUPERFAMILY SSF51905 25 241 5.61E-56 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS21320 74069ceed58104e61c5d552f42b3d7de 517 SUPERFAMILY SSF51905 311 426 5.61E-56 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS21320 74069ceed58104e61c5d552f42b3d7de 517 Gene3D G3DSA:3.50.50.60 17 234 2.0E-64 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS21320 74069ceed58104e61c5d552f42b3d7de 517 Gene3D G3DSA:3.50.50.60 336 502 1.1E-20 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS16360 ddf86f0fc10e87968e88a8efbe32909c 324 Gene3D G3DSA:3.60.110.10 5 268 3.6E-45 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 BWK49_RS16360 ddf86f0fc10e87968e88a8efbe32909c 324 Pfam PF00795 Carbon-nitrogen hydrolase 6 159 3.4E-19 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 BWK49_RS16360 ddf86f0fc10e87968e88a8efbe32909c 324 SUPERFAMILY SSF56317 1 269 2.09E-42 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 BWK49_RS11285 8aff90df318e3b63f3b0dda8aaebc727 161 Gene3D G3DSA:1.20.120.520 51 127 3.6E-11 T 06-07-2017 BWK49_RS11285 8aff90df318e3b63f3b0dda8aaebc727 161 Pfam PF01814 Hemerythrin HHE cation binding domain 8 122 1.4E-13 T 06-07-2017 IPR012312 Haemerythrin-like Reactome: R-HSA-390471 BWK49_RS11285 8aff90df318e3b63f3b0dda8aaebc727 161 Gene3D G3DSA:1.20.120.520 8 50 2.8E-4 T 06-07-2017 BWK49_RS12125 0877fbd77fe631365dd50e8c1c69b54c 118 Pfam PF01022 Bacterial regulatory protein, arsR family 34 81 5.2E-16 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 BWK49_RS12125 0877fbd77fe631365dd50e8c1c69b54c 118 SUPERFAMILY SSF46785 14 106 3.41E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS12125 0877fbd77fe631365dd50e8c1c69b54c 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 64 79 3.3E-21 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 BWK49_RS12125 0877fbd77fe631365dd50e8c1c69b54c 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 79 94 3.3E-21 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 BWK49_RS12125 0877fbd77fe631365dd50e8c1c69b54c 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 29 44 3.3E-21 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 BWK49_RS12125 0877fbd77fe631365dd50e8c1c69b54c 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 51 62 3.3E-21 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 BWK49_RS12125 0877fbd77fe631365dd50e8c1c69b54c 118 SMART SM00418 27 108 1.9E-27 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 BWK49_RS12125 0877fbd77fe631365dd50e8c1c69b54c 118 Gene3D G3DSA:1.10.10.10 8 106 2.1E-32 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS03600 9afa1366b06e696d3e22f5e543e76ca7 280 Pfam PF02405 Permease MlaE 64 267 7.0E-52 T 06-07-2017 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 BWK49_RS11050 69d3cd9a5d17cbee881907d7b8c811bb 271 Gene3D G3DSA:3.90.226.10 3 262 1.1E-65 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS11050 69d3cd9a5d17cbee881907d7b8c811bb 271 Pfam PF00378 Enoyl-CoA hydratase/isomerase 13 262 3.7E-48 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 BWK49_RS11050 69d3cd9a5d17cbee881907d7b8c811bb 271 SUPERFAMILY SSF52096 4 263 4.54E-67 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS24200 f828033053c6a5eaed8c523ec5a189c7 304 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 17 275 4.0E-85 T 06-07-2017 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 BWK49_RS24200 f828033053c6a5eaed8c523ec5a189c7 304 Gene3D G3DSA:3.40.50.150 16 217 1.3E-18 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS24200 f828033053c6a5eaed8c523ec5a189c7 304 SUPERFAMILY SSF53335 15 289 1.99E-82 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS24200 f828033053c6a5eaed8c523ec5a189c7 304 Pfam PF04072 Leucine carboxyl methyltransferase 19 203 1.1E-69 T 06-07-2017 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 BWK49_RS08365 2e018a9dcadc03d3efdd761dde34da4e 557 Pfam PF00823 PPE family 8 164 1.5E-60 T 06-07-2017 IPR000030 PPE family BWK49_RS08365 2e018a9dcadc03d3efdd761dde34da4e 557 SUPERFAMILY SSF140459 5 177 7.32E-61 T 06-07-2017 BWK49_RS05510 df7a3aeb959bf65fa654bec72c3dbada 165 SUPERFAMILY SSF52540 8 121 2.96E-16 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS05510 df7a3aeb959bf65fa654bec72c3dbada 165 SMART SM00382 7 145 0.0012 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS05510 df7a3aeb959bf65fa654bec72c3dbada 165 Gene3D G3DSA:3.40.50.300 12 137 1.3E-19 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS05510 df7a3aeb959bf65fa654bec72c3dbada 165 Pfam PF01695 IstB-like ATP binding protein 9 138 2.6E-33 T 06-07-2017 IPR002611 IstB-like ATP-binding protein GO:0005524 BWK49_RS22515 010d6bee1e66e911cb478a58028e7bb3 324 Gene3D G3DSA:3.20.20.140 3 323 3.4E-98 T 06-07-2017 BWK49_RS22515 010d6bee1e66e911cb478a58028e7bb3 324 Pfam PF02126 Phosphotriesterase family 11 322 3.4E-90 T 06-07-2017 IPR001559 Phosphotriesterase GO:0008270|GO:0009056 BWK49_RS22515 010d6bee1e66e911cb478a58028e7bb3 324 SUPERFAMILY SSF51556 2 323 4.81E-78 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS00085 217f493be0868592aea39eca2f4f4d44 141 Pfam PF10756 Bacterial PH domain 58 135 7.5E-21 T 06-07-2017 IPR019692 Protein of unknown function DUF2581 BWK49_RS27295 1f760cba12b85409c162a17c02583138 158 Pfam PF03061 Thioesterase superfamily 35 115 1.3E-13 T 06-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 BWK49_RS27295 1f760cba12b85409c162a17c02583138 158 SUPERFAMILY SSF54637 17 149 7.89E-35 T 06-07-2017 IPR029069 HotDog domain BWK49_RS27295 1f760cba12b85409c162a17c02583138 158 Gene3D G3DSA:3.10.129.10 15 150 2.9E-44 T 06-07-2017 IPR029069 HotDog domain BWK49_RS04285 304761e9bdd5e96139c1d39870dfdaf5 161 Gene3D G3DSA:3.30.300.20 6 78 3.6E-20 T 06-07-2017 IPR015946 K homology domain-like, alpha/beta BWK49_RS04285 304761e9bdd5e96139c1d39870dfdaf5 161 SUPERFAMILY SSF54814 6 78 1.9E-18 T 06-07-2017 IPR009019 K homology domain, prokaryotic type GO:0003723 BWK49_RS04285 304761e9bdd5e96139c1d39870dfdaf5 161 Gene3D G3DSA:3.30.300.20 80 144 7.2E-13 T 06-07-2017 IPR015946 K homology domain-like, alpha/beta BWK49_RS04285 304761e9bdd5e96139c1d39870dfdaf5 161 Pfam PF13184 NusA-like KH domain 31 89 1.3E-12 T 06-07-2017 IPR025249 KH domain, NusA-like GO:0003723 BWK49_RS04285 304761e9bdd5e96139c1d39870dfdaf5 161 SUPERFAMILY SSF54814 81 141 1.24E-7 T 06-07-2017 IPR009019 K homology domain, prokaryotic type GO:0003723 BWK49_RS17970 2f39c42e11a4611169548ac64dbaa7c8 142 Pfam PF01042 Endoribonuclease L-PSP 18 136 1.3E-17 T 06-07-2017 IPR006175 YjgF/YER057c/UK114 family BWK49_RS17970 2f39c42e11a4611169548ac64dbaa7c8 142 SUPERFAMILY SSF55298 13 137 2.04E-23 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like BWK49_RS17970 2f39c42e11a4611169548ac64dbaa7c8 142 Gene3D G3DSA:3.30.1330.40 2 137 1.5E-30 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like BWK49_RS07435 51de2441e0262d3384925010d561e4cf 191 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 17 30 - T 06-07-2017 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 BWK49_RS07435 51de2441e0262d3384925010d561e4cf 191 Pfam PF01195 Peptidyl-tRNA hydrolase 6 187 6.5E-56 T 06-07-2017 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 BWK49_RS07435 51de2441e0262d3384925010d561e4cf 191 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 5 189 8.4E-58 T 06-07-2017 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 BWK49_RS07435 51de2441e0262d3384925010d561e4cf 191 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 111 121 - T 06-07-2017 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 BWK49_RS07435 51de2441e0262d3384925010d561e4cf 191 Gene3D G3DSA:3.40.50.1470 3 189 2.3E-70 T 06-07-2017 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 BWK49_RS07435 51de2441e0262d3384925010d561e4cf 191 SUPERFAMILY SSF53178 5 189 3.53E-64 T 06-07-2017 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 BWK49_RS07435 51de2441e0262d3384925010d561e4cf 191 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 4 182 34.551 T 06-07-2017 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 BWK49_RS21050 11ade0914627af79b106e07f913fae26 338 Gene3D G3DSA:3.20.20.210 91 334 5.7E-13 T 06-07-2017 BWK49_RS21050 11ade0914627af79b106e07f913fae26 338 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 10 328 2.7E-58 T 06-07-2017 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 BWK49_RS21050 11ade0914627af79b106e07f913fae26 338 SUPERFAMILY SSF51726 10 332 8.63E-28 T 06-07-2017 BWK49_RS14615 656bfeb0a65df09d82778acb93ecd676 164 SUPERFAMILY SSF55961 3 150 2.04E-13 T 06-07-2017 BWK49_RS14615 656bfeb0a65df09d82778acb93ecd676 164 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 1 147 4.3E-7 T 06-07-2017 IPR019587 Polyketide cyclase/dehydrase BWK49_RS04530 9357a853541e16d998adee7fda3ec9eb 197 Gene3D G3DSA:1.10.10.60 30 74 3.2E-4 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS04670 6185331a0abac0d5e02c3b68e1e04f0c 424 Pfam PF01610 Transposase 154 409 5.5E-59 T 06-07-2017 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain BWK49_RS04670 6185331a0abac0d5e02c3b68e1e04f0c 424 Pfam PF13542 Helix-turn-helix domain of transposase family ISL3 88 134 1.3E-10 T 06-07-2017 IPR032877 Transposase IS204/IS1001/IS1096/IS1165, helix-turn-helix domain BWK49_RS04670 6185331a0abac0d5e02c3b68e1e04f0c 424 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 32 72 3.3E-6 T 06-07-2017 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger BWK49_RS12470 b12efbf38bd28787cc489c268cfa0737 440 Gene3D G3DSA:1.10.10.60 353 384 7.8E-5 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS12470 b12efbf38bd28787cc489c268cfa0737 440 Pfam PF13556 PucR C-terminal helix-turn-helix domain 349 405 5.2E-21 T 06-07-2017 IPR025736 PucR C-terminal helix-turn-helix domain BWK49_RS10540 428b9b4447487ebce08495db64803278 87 Pfam PF09851 Short C-terminal domain 60 80 4.8E-7 T 06-07-2017 IPR018649 SHOCT domain BWK49_RS27510 cecb66bef9c6cfd181d635d091dab14f 126 Pfam PF04248 Domain of unknown function (DUF427) 24 116 1.2E-31 T 06-07-2017 IPR007361 Domain of unknown function DUF427 BWK49_RS04765 073c41a57aba40b30cabf1cfc9c03da1 352 Pfam PF16169 Domain of unknown function (DUF4872) 160 344 2.3E-44 T 06-07-2017 IPR032369 Domain of unknown function DUF4872 BWK49_RS04765 073c41a57aba40b30cabf1cfc9c03da1 352 Pfam PF14399 Butirosin biosynthesis protein H, N-terminal 15 149 1.2E-40 T 06-07-2017 IPR026935 Butirosin biosynthesis protein H, N-terminal KEGG: 00524+2.3.2.19|MetaCyc: PWY-7019 BWK49_RS01935 5046323ec518c552b83b18bd93d0e2b4 164 Pfam PF13276 HTH-like domain 81 123 6.0E-10 T 06-07-2017 IPR025948 HTH-like domain BWK49_RS28450 6f6107ca06876cdc7412dd181a502988 462 TIGRFAM TIGR00797 matE: MATE efflux family protein 22 436 3.7E-44 T 06-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 BWK49_RS28450 6f6107ca06876cdc7412dd181a502988 462 Pfam PF01554 MatE 22 191 3.3E-7 T 06-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 BWK49_RS28450 6f6107ca06876cdc7412dd181a502988 462 Pfam PF01554 MatE 274 420 1.8E-20 T 06-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 BWK49_RS21865 822aad95841079a6623d9b8d86de327d 330 Gene3D G3DSA:3.40.109.10 9 69 2.6E-28 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 BWK49_RS21865 822aad95841079a6623d9b8d86de327d 330 Gene3D G3DSA:3.40.109.10 138 187 2.6E-28 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 BWK49_RS21865 822aad95841079a6623d9b8d86de327d 330 Gene3D G3DSA:3.40.109.10 231 322 2.6E-28 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 BWK49_RS21865 822aad95841079a6623d9b8d86de327d 330 Pfam PF00881 Nitroreductase family 235 300 1.2E-4 T 06-07-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 BWK49_RS21865 822aad95841079a6623d9b8d86de327d 330 SUPERFAMILY SSF55469 10 64 7.52E-18 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 BWK49_RS21865 822aad95841079a6623d9b8d86de327d 330 SUPERFAMILY SSF55469 223 322 7.52E-18 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 BWK49_RS22395 ad3fb3a012aaf688cc95ea4db73ff88d 435 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 155 435 4.4E-105 T 06-07-2017 IPR024516 Mammalian cell entry, C-terminal BWK49_RS22395 ad3fb3a012aaf688cc95ea4db73ff88d 435 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 20 304 1.5E-74 T 06-07-2017 IPR005693 Virulence factor Mce protein BWK49_RS22395 ad3fb3a012aaf688cc95ea4db73ff88d 435 Pfam PF02470 MlaD protein 46 125 6.6E-13 T 06-07-2017 IPR003399 Mce/MlaD BWK49_RS05585 65e006e06c406289005c2162610483d6 186 Pfam PF00872 Transposase, Mutator family 29 166 1.3E-20 T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 BWK49_RS23730 46e1c6b35dde54d25caba47a894081ff 527 SUPERFAMILY SSF140459 5 177 4.45E-61 T 06-07-2017 BWK49_RS23730 46e1c6b35dde54d25caba47a894081ff 527 Pfam PF00823 PPE family 8 164 2.2E-59 T 06-07-2017 IPR000030 PPE family BWK49_RS09490 79f691d79e2d5b8797963f5ccfa17ba5 347 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 62 7.5E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS09490 79f691d79e2d5b8797963f5ccfa17ba5 347 Pfam PF03061 Thioesterase superfamily 244 316 9.5E-11 T 06-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 BWK49_RS09490 79f691d79e2d5b8797963f5ccfa17ba5 347 SUPERFAMILY SSF48498 103 198 6.07E-7 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS09490 79f691d79e2d5b8797963f5ccfa17ba5 347 Gene3D G3DSA:3.10.129.10 214 336 1.1E-27 T 06-07-2017 IPR029069 HotDog domain BWK49_RS09490 79f691d79e2d5b8797963f5ccfa17ba5 347 Gene3D G3DSA:1.10.357.10 14 177 1.6E-22 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS09490 79f691d79e2d5b8797963f5ccfa17ba5 347 SUPERFAMILY SSF54637 225 335 3.64E-22 T 06-07-2017 IPR029069 HotDog domain BWK49_RS09490 79f691d79e2d5b8797963f5ccfa17ba5 347 SUPERFAMILY SSF46689 12 83 6.16E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS09490 79f691d79e2d5b8797963f5ccfa17ba5 347 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 226 314 3.8E-15 T 06-07-2017 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-75105 BWK49_RS27960 3889948060b0a7337cff45480c81dfc8 137 Gene3D G3DSA:3.10.450.50 2 131 2.4E-35 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS27960 3889948060b0a7337cff45480c81dfc8 137 SUPERFAMILY SSF54427 3 129 3.55E-37 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS27960 3889948060b0a7337cff45480c81dfc8 137 Pfam PF13577 SnoaL-like domain 3 125 3.7E-30 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain BWK49_RS03360 7552ed3927c1b7db0d42120a80db5cd1 247 SUPERFAMILY SSF100950 3 244 1.42E-51 T 06-07-2017 BWK49_RS03360 7552ed3927c1b7db0d42120a80db5cd1 247 Gene3D G3DSA:3.40.810.20 4 245 4.1E-65 T 06-07-2017 BWK49_RS03360 7552ed3927c1b7db0d42120a80db5cd1 247 SMART SM00882 7 207 7.3E-4 T 06-07-2017 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 BWK49_RS22355 9ef0352a94a26b2c1aaa9e147f2a0bf3 302 PIRSF PIRSF007580 9 302 1.0E-129 T 06-07-2017 IPR016516 Uncharacterised conserved protein UCP07580 BWK49_RS22355 9ef0352a94a26b2c1aaa9e147f2a0bf3 302 Pfam PF10118 Predicted metal-dependent hydrolase 24 282 1.5E-73 T 06-07-2017 IPR016516 Uncharacterised conserved protein UCP07580 BWK49_RS11145 2f2095df1ec375763849c12e87c919a3 361 SUPERFAMILY SSF51735 1 143 1.97E-11 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS11145 2f2095df1ec375763849c12e87c919a3 361 Gene3D G3DSA:3.40.50.720 1 206 1.4E-21 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS11145 2f2095df1ec375763849c12e87c919a3 361 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 1 96 8.0E-6 T 06-07-2017 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 BWK49_RS21510 e69971d199363a3bc321ee8197c07fe4 132 Pfam PF05423 Mycobacterium membrane protein 1 132 1.7E-30 T 06-07-2017 IPR008693 Transport accessory protein MmpS BWK49_RS11590 6b8494847b26dda9fedcbfe9d18a084c 155 ProDom PD091785 LIPOPROTEIN LPPP PALMITATE MEMBRANE PRECURSOR SIGNAL 3 155 5.0E-78 T 06-07-2017 IPR020217 Uncharacterised protein family, lipoprotein LppP BWK49_RS11590 6b8494847b26dda9fedcbfe9d18a084c 155 Pfam PF14041 LppP/LprE lipoprotein 59 142 5.5E-29 T 06-07-2017 IPR025971 LppP/LprE lipoprotein BWK49_RS00035 4e0d90bc174b0b64bf09d9c42711ad9b 291 Pfam PF12089 Transmembrane domain of unknown function (DUF3566) 174 289 4.7E-41 T 06-07-2017 IPR021949 Domain of unknown function DUF3566. transmembrane BWK49_RS17980 afad287942a9aa29a1d4777149982d7c 128 Gene3D G3DSA:3.40.630.30 23 112 2.0E-15 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase BWK49_RS17980 afad287942a9aa29a1d4777149982d7c 128 Pfam PF14542 GCN5-related N-acetyl-transferase 31 108 1.6E-13 T 06-07-2017 IPR031165 Yjdj-type Gcn5-related N-acetyltransferase BWK49_RS17980 afad287942a9aa29a1d4777149982d7c 128 SUPERFAMILY SSF55729 23 110 1.1E-16 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase BWK49_RS11640 89ba921d2d8748e048228f9c9deec43a 294 SUPERFAMILY SSF161098 57 279 6.41E-54 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS11640 89ba921d2d8748e048228f9c9deec43a 294 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 287 6.5E-16 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS11640 89ba921d2d8748e048228f9c9deec43a 294 Gene3D G3DSA:1.10.3720.10 63 288 7.9E-60 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS17595 e2513c291934dac05d235a28ea5fe1cb 189 Pfam PF02627 Carboxymuconolactone decarboxylase family 40 122 1.6E-16 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 BWK49_RS17595 e2513c291934dac05d235a28ea5fe1cb 189 SUPERFAMILY SSF69118 32 174 9.29E-30 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 BWK49_RS17595 e2513c291934dac05d235a28ea5fe1cb 189 Gene3D G3DSA:1.20.1290.10 32 175 1.4E-33 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 BWK49_RS28035 7aecc14cba68fdaa09a6c6f916b87266 354 SUPERFAMILY SSF159245 136 261 8.63E-5 T 06-07-2017 BWK49_RS13735 66f7c987481afa4b2fb1bb19fa46fcb8 192 SUPERFAMILY SSF52540 1 142 4.2E-11 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS13735 66f7c987481afa4b2fb1bb19fa46fcb8 192 Pfam PF06414 Zeta toxin 5 136 3.7E-11 T 06-07-2017 IPR010488 Zeta toxin domain GO:0005524|GO:0016301 BWK49_RS13735 66f7c987481afa4b2fb1bb19fa46fcb8 192 Gene3D G3DSA:3.40.50.300 3 140 2.5E-15 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS14085 4cea0e6dfb3b353e157cd1b0d46ab31d 266 Gene3D G3DSA:2.30.110.10 141 236 2.8E-10 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 BWK49_RS14085 4cea0e6dfb3b353e157cd1b0d46ab31d 266 TIGRFAM TIGR03666 Rv2061_F420: PPOX class probable F420-dependent enzyme, Rv2061 family 139 265 7.7E-29 T 06-07-2017 IPR019965 PPOX class F420-dependent enzyme, family Rv2061, putative BWK49_RS14085 4cea0e6dfb3b353e157cd1b0d46ab31d 266 SUPERFAMILY SSF50475 145 265 1.04E-12 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 BWK49_RS06780 d56e827130a8eb94cb3a03f32ab05005 162 Gene3D G3DSA:3.10.180.10 32 146 2.7E-11 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS06780 d56e827130a8eb94cb3a03f32ab05005 162 SUPERFAMILY SSF54593 22 139 2.48E-14 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS03210 a62074792207bcf08763c2a05f061898 252 Pfam PF03746 LamB/YcsF family 4 241 1.8E-98 T 06-07-2017 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF BWK49_RS03210 a62074792207bcf08763c2a05f061898 252 SUPERFAMILY SSF88713 4 251 5.11E-94 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 BWK49_RS03210 a62074792207bcf08763c2a05f061898 252 Hamap MF_00691 UPF0271 protein YbgL [ybgL]. 2 246 43.712 T 06-07-2017 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF BWK49_RS21990 94112f75bd23e94e3774a01b433a3f88 125 Hamap MF_01394 NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic [ndhC]. 1 125 17.266 T 06-07-2017 IPR023043 NAD(P)H-quinone oxidoreductase subunit 3, bacterial/plastid GO:0016651|GO:0055114 BWK49_RS21990 94112f75bd23e94e3774a01b433a3f88 125 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 20 124 1.2E-34 T 06-07-2017 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS28680 e14be7a41610724f5637725f8af2fcc6 431 Gene3D G3DSA:3.40.50.2000 2 261 1.3E-56 T 06-07-2017 BWK49_RS28680 e14be7a41610724f5637725f8af2fcc6 431 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 5 94 4.9E-10 T 06-07-2017 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 BWK49_RS28680 e14be7a41610724f5637725f8af2fcc6 431 SUPERFAMILY SSF53756 2 420 3.93E-85 T 06-07-2017 BWK49_RS28680 e14be7a41610724f5637725f8af2fcc6 431 Gene3D G3DSA:3.40.50.2000 262 391 2.8E-7 T 06-07-2017 BWK49_RS22690 539deb2dcba672ceaa1cedb44259da0b 88 Pfam PF11305 Protein of unknown function (DUF3107) 1 73 8.5E-28 T 06-07-2017 IPR021456 Protein of unknown function DUF3107 BWK49_RS13425 1c9d3684af97f620e51336057c2fe7c9 452 Hamap MF_02111 Pup--protein ligase [pafA]. 1 452 50.418 T 06-07-2017 IPR022279 Pup--protein ligase GO:0010498|GO:0016879|GO:0019941 BWK49_RS13425 1c9d3684af97f620e51336057c2fe7c9 452 Pfam PF03136 Pup-ligase protein 4 422 4.6E-159 T 06-07-2017 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 BWK49_RS13425 1c9d3684af97f620e51336057c2fe7c9 452 TIGRFAM TIGR03686 pupylate_PafA: Pup--protein ligase 3 452 1.1E-240 T 06-07-2017 IPR022279 Pup--protein ligase GO:0010498|GO:0016879|GO:0019941 BWK49_RS13425 1c9d3684af97f620e51336057c2fe7c9 452 PIRSF PIRSF018077 1 452 1.9E-186 T 06-07-2017 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 BWK49_RS12515 295cc2bc2437bbda1d7a40f601c5c225 314 Pfam PF03186 CobD/Cbib protein 11 292 1.6E-87 T 06-07-2017 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 BWK49_RS12515 295cc2bc2437bbda1d7a40f601c5c225 314 TIGRFAM TIGR00380 cobD: cobalamin biosynthesis protein CobD 14 267 9.0E-52 T 06-07-2017 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 BWK49_RS12515 295cc2bc2437bbda1d7a40f601c5c225 314 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 314 90.446 T 06-07-2017 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 BWK49_RS08375 da2246e818204bb1aaa5ec840c0718d2 543 TIGRFAM TIGR01236 D1pyr5carbox1: 1-pyrroline-5-carboxylate dehydrogenase 11 540 1.2E-260 T 06-07-2017 IPR005931 Delta-1-pyrroline-5-carboxylate dehydrogenase GO:0003842|GO:0006537|GO:0006561 KEGG: 00250+1.2.1.88|KEGG: 00330+1.2.1.88|MetaCyc: PWY-6853|Reactome: R-HSA-70688 BWK49_RS08375 da2246e818204bb1aaa5ec840c0718d2 543 Gene3D G3DSA:3.40.309.10 307 499 2.7E-37 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 BWK49_RS08375 da2246e818204bb1aaa5ec840c0718d2 543 SUPERFAMILY SSF53720 8 526 1.7E-112 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 BWK49_RS08375 da2246e818204bb1aaa5ec840c0718d2 543 Gene3D G3DSA:3.40.605.10 40 306 5.2E-57 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 BWK49_RS08375 da2246e818204bb1aaa5ec840c0718d2 543 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 320 331 - T 06-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 BWK49_RS08375 da2246e818204bb1aaa5ec840c0718d2 543 Pfam PF00171 Aldehyde dehydrogenase family 53 521 7.2E-90 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 BWK49_RS10025 ffad74b3af0fb1422537fd39d1accaec 181 Pfam PF00857 Isochorismatase family 4 176 4.0E-27 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 BWK49_RS10025 ffad74b3af0fb1422537fd39d1accaec 181 Gene3D G3DSA:3.40.50.850 1 178 7.8E-36 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 BWK49_RS10025 ffad74b3af0fb1422537fd39d1accaec 181 SUPERFAMILY SSF52499 2 179 3.14E-38 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 BWK49_RS22740 80bb108e0eba3999c22cef0efc7a72c5 321 Pfam PF00781 Diacylglycerol kinase catalytic domain 3 119 2.3E-25 T 06-07-2017 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 BWK49_RS22740 80bb108e0eba3999c22cef0efc7a72c5 321 Gene3D G3DSA:3.40.50.10330 2 101 4.9E-6 T 06-07-2017 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 BWK49_RS22740 80bb108e0eba3999c22cef0efc7a72c5 321 SUPERFAMILY SSF111331 1 317 2.01E-48 T 06-07-2017 IPR016064 NAD kinase/diacylglycerol kinase-like domain BWK49_RS22740 80bb108e0eba3999c22cef0efc7a72c5 321 SMART SM00046 2 172 9.5E-24 T 06-07-2017 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 BWK49_RS19985 1ad3f0ae1ab75508fac043c269f2590c 333 Gene3D G3DSA:3.40.50.1820 34 319 9.6E-20 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS19985 1ad3f0ae1ab75508fac043c269f2590c 333 Pfam PF12146 Serine aminopeptidase, S33 42 165 5.2E-13 T 06-07-2017 IPR022742 Serine aminopeptidase, S33 BWK49_RS19985 1ad3f0ae1ab75508fac043c269f2590c 333 SUPERFAMILY SSF53474 38 315 9.4E-21 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS08330 bc5e7b322d23993c5746ee4ea1a3930b 385 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 300 381 2.5E-13 T 06-07-2017 IPR022171 PPE family, C-terminal BWK49_RS08330 bc5e7b322d23993c5746ee4ea1a3930b 385 Pfam PF00823 PPE family 6 163 1.4E-60 T 06-07-2017 IPR000030 PPE family BWK49_RS08330 bc5e7b322d23993c5746ee4ea1a3930b 385 SUPERFAMILY SSF140459 3 175 2.12E-62 T 06-07-2017 BWK49_RS03025 8d3e46ad2cfdc06f55359e1ab388f5fd 527 Pfam PF02720 Domain of unknown function (DUF222) 18 330 2.3E-78 T 06-07-2017 IPR003870 Domain of unknown function DUF222 BWK49_RS03025 8d3e46ad2cfdc06f55359e1ab388f5fd 527 SMART SM00507 321 378 0.0037 T 06-07-2017 IPR003615 HNH nuclease BWK49_RS09525 3b82e7b03fe14e7da189a595305ab214 238 Pfam PF00106 short chain dehydrogenase 3 179 7.5E-44 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS09525 3b82e7b03fe14e7da189a595305ab214 238 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 126 154 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS09525 3b82e7b03fe14e7da189a595305ab214 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 113 129 1.1E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS09525 3b82e7b03fe14e7da189a595305ab214 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 177 1.1E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS09525 3b82e7b03fe14e7da189a595305ab214 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 1.1E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS09525 3b82e7b03fe14e7da189a595305ab214 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 139 158 1.1E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS09525 3b82e7b03fe14e7da189a595305ab214 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 68 79 1.1E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS09525 3b82e7b03fe14e7da189a595305ab214 238 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 68 79 4.3E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS09525 3b82e7b03fe14e7da189a595305ab214 238 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 158 4.3E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS09525 3b82e7b03fe14e7da189a595305ab214 238 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2 170 9.7E-4 T 06-07-2017 BWK49_RS09525 3b82e7b03fe14e7da189a595305ab214 238 Gene3D G3DSA:3.40.50.720 2 199 2.8E-55 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS09525 3b82e7b03fe14e7da189a595305ab214 238 SUPERFAMILY SSF51735 2 200 3.06E-55 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS22700 7f4b878c5500386a3a3036500f3dea0b 235 Pfam PF13794 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like 28 206 9.4E-59 T 06-07-2017 BWK49_RS22700 7f4b878c5500386a3a3036500f3dea0b 235 SUPERFAMILY SSF47240 26 141 3.19E-8 T 06-07-2017 IPR009078 Ferritin-like superfamily BWK49_RS22700 7f4b878c5500386a3a3036500f3dea0b 235 Gene3D G3DSA:1.20.1260.10 62 118 2.1E-4 T 06-07-2017 IPR012347 Ferritin-related BWK49_RS07110 cf724c7f59719900b41319e668bf273b 112 Pfam PF09723 Zinc ribbon domain 2 40 1.3E-11 T 06-07-2017 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain BWK49_RS07110 cf724c7f59719900b41319e668bf273b 112 SMART SM00834 2 41 4.2E-9 T 06-07-2017 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain BWK49_RS07110 cf724c7f59719900b41319e668bf273b 112 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 2 51 2.7E-16 T 06-07-2017 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain BWK49_RS13675 f15ad346b14721c0a8c693ea573f765b 199 SUPERFAMILY SSF46689 9 90 4.93E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS13675 f15ad346b14721c0a8c693ea573f765b 199 Gene3D G3DSA:1.10.357.10 8 198 3.4E-25 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS13675 f15ad346b14721c0a8c693ea573f765b 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 67 2.8E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS13675 f15ad346b14721c0a8c693ea573f765b 199 SUPERFAMILY SSF48498 102 196 6.92E-5 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS13675 f15ad346b14721c0a8c693ea573f765b 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 6.1E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS13675 f15ad346b14721c0a8c693ea573f765b 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 6.1E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS12105 cf4b90e7fa10d7756ee387737f4fb693 220 Pfam PF00440 Bacterial regulatory proteins, tetR family 30 76 1.2E-15 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS12105 cf4b90e7fa10d7756ee387737f4fb693 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 43 2.1E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS12105 cf4b90e7fa10d7756ee387737f4fb693 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 51 74 2.1E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS12105 cf4b90e7fa10d7756ee387737f4fb693 220 Gene3D G3DSA:1.10.357.10 21 216 4.7E-31 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS12105 cf4b90e7fa10d7756ee387737f4fb693 220 SUPERFAMILY SSF46689 19 95 2.59E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS20615 0a9c1c2391d646478df00c6bde608b0d 555 Pfam PF01566 Natural resistance-associated macrophage protein 76 428 4.2E-76 T 06-07-2017 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 BWK49_RS05375 42bb4f89f7523b7329002124ef9f8a2d 155 SUPERFAMILY SSF56349 34 153 1.09E-5 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 BWK49_RS28585 1460a4900b1338900f929c5ce3190489 106 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 3 101 1.0E-17 T 06-07-2017 IPR003477 mRNA interferase PemK-like protein GO:0003677 BWK49_RS28585 1460a4900b1338900f929c5ce3190489 106 SUPERFAMILY SSF50118 2 104 5.56E-21 T 06-07-2017 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor BWK49_RS28585 1460a4900b1338900f929c5ce3190489 106 Gene3D G3DSA:2.30.30.110 3 104 1.3E-14 T 06-07-2017 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor BWK49_RS01080 4bda750c4ac9c84a0321df3bd5264e9c 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 62 5.9E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS01080 4bda750c4ac9c84a0321df3bd5264e9c 212 Gene3D G3DSA:1.10.357.10 59 197 1.0E-21 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS01080 4bda750c4ac9c84a0321df3bd5264e9c 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 1.0E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS01080 4bda750c4ac9c84a0321df3bd5264e9c 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 1.0E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS01080 4bda750c4ac9c84a0321df3bd5264e9c 212 Gene3D G3DSA:1.10.10.60 3 58 4.0E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS01080 4bda750c4ac9c84a0321df3bd5264e9c 212 SUPERFAMILY SSF46689 2 66 2.13E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS01080 4bda750c4ac9c84a0321df3bd5264e9c 212 ProSitePatterns PS01081 TetR-type HTH domain signature. 29 60 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site BWK49_RS15370 a47e5b75a4d4f42b45356e90f975a914 287 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 276 3.4E-34 T 06-07-2017 BWK49_RS15370 a47e5b75a4d4f42b45356e90f975a914 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 137 153 1.5E-21 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15370 a47e5b75a4d4f42b45356e90f975a914 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 241 261 1.5E-21 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15370 a47e5b75a4d4f42b45356e90f975a914 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 191 1.5E-21 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15370 a47e5b75a4d4f42b45356e90f975a914 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.5E-21 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15370 a47e5b75a4d4f42b45356e90f975a914 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 94 105 1.5E-21 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15370 a47e5b75a4d4f42b45356e90f975a914 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 193 210 1.5E-21 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS15370 a47e5b75a4d4f42b45356e90f975a914 287 TIGRFAM TIGR03971 SDR_subfam_1: SDR family mycofactocin-dependent oxidoreductase 4 278 2.3E-101 T 06-07-2017 IPR023985 Mycofactocin-dependent oxidoreductase BWK49_RS15370 a47e5b75a4d4f42b45356e90f975a914 287 Gene3D G3DSA:3.40.50.720 1 276 7.9E-61 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS15370 a47e5b75a4d4f42b45356e90f975a914 287 SUPERFAMILY SSF51735 1 278 3.58E-54 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS25935 3f2c7199e6f44e0b4caeeabe81246244 167 Gene3D G3DSA:3.40.630.30 20 150 2.5E-21 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase BWK49_RS25935 3f2c7199e6f44e0b4caeeabe81246244 167 Pfam PF00583 Acetyltransferase (GNAT) family 64 144 7.3E-11 T 06-07-2017 IPR000182 GNAT domain GO:0008080 BWK49_RS25935 3f2c7199e6f44e0b4caeeabe81246244 167 SUPERFAMILY SSF55729 18 159 5.49E-20 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase BWK49_RS16700 33cdcfa608bf6698577fe246fddefae4 426 TIGRFAM TIGR00836 amt: ammonium transporter 9 406 2.1E-134 T 06-07-2017 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 BWK49_RS16700 33cdcfa608bf6698577fe246fddefae4 426 ProSitePatterns PS01219 Ammonium transporters signature. 162 187 - T 06-07-2017 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 BWK49_RS16700 33cdcfa608bf6698577fe246fddefae4 426 Gene3D G3DSA:1.10.3430.10 4 387 2.4E-131 T 06-07-2017 IPR029020 Ammonium/urea transporter BWK49_RS16700 33cdcfa608bf6698577fe246fddefae4 426 Pfam PF00909 Ammonium Transporter Family 10 406 5.7E-123 T 06-07-2017 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 BWK49_RS16700 33cdcfa608bf6698577fe246fddefae4 426 SUPERFAMILY SSF111352 5 387 1.96E-120 T 06-07-2017 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 BWK49_RS13565 cedd1362605143efa3343ac41c30f371 215 Gene3D G3DSA:1.10.357.10 6 203 5.7E-31 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS13565 cedd1362605143efa3343ac41c30f371 215 SUPERFAMILY SSF46689 16 80 2.52E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS13565 cedd1362605143efa3343ac41c30f371 215 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 68 3.8E-12 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS13565 cedd1362605143efa3343ac41c30f371 215 SUPERFAMILY SSF48498 132 198 3.21E-5 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS13565 cedd1362605143efa3343ac41c30f371 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 66 1.2E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS13565 cedd1362605143efa3343ac41c30f371 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 35 1.2E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS13565 cedd1362605143efa3343ac41c30f371 215 ProSitePatterns PS01081 TetR-type HTH domain signature. 34 65 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site BWK49_RS14360 4dffa8bc854da4e87c6a129439586d42 252 Pfam PF08241 Methyltransferase domain 19 121 3.0E-18 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 BWK49_RS14360 4dffa8bc854da4e87c6a129439586d42 252 SUPERFAMILY SSF53335 7 191 7.0E-35 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS14360 4dffa8bc854da4e87c6a129439586d42 252 Gene3D G3DSA:3.40.50.150 7 236 3.3E-40 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS27240 0862ee617c263bc6406d79e5ab742947 516 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 9 293 3.5E-86 T 06-07-2017 IPR005693 Virulence factor Mce protein BWK49_RS27240 0862ee617c263bc6406d79e5ab742947 516 Pfam PF02470 MlaD protein 40 112 3.3E-17 T 06-07-2017 IPR003399 Mce/MlaD BWK49_RS27240 0862ee617c263bc6406d79e5ab742947 516 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 153 280 7.4E-7 T 06-07-2017 IPR024516 Mammalian cell entry, C-terminal BWK49_RS23030 871e80f7f45bb3836eb0c85a5d8fba29 358 SUPERFAMILY SSF53448 8 307 6.1E-69 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases BWK49_RS23030 871e80f7f45bb3836eb0c85a5d8fba29 358 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 254 285 5.3E-5 T 06-07-2017 IPR001451 Hexapeptide repeat BWK49_RS23030 871e80f7f45bb3836eb0c85a5d8fba29 358 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 304 335 7.5E-4 T 06-07-2017 IPR001451 Hexapeptide repeat BWK49_RS23030 871e80f7f45bb3836eb0c85a5d8fba29 358 Gene3D G3DSA:2.160.10.10 253 350 1.9E-17 T 06-07-2017 BWK49_RS23030 871e80f7f45bb3836eb0c85a5d8fba29 358 Pfam PF00483 Nucleotidyl transferase 9 234 1.4E-42 T 06-07-2017 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 BWK49_RS23030 871e80f7f45bb3836eb0c85a5d8fba29 358 Gene3D G3DSA:3.90.550.10 7 237 1.4E-66 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases BWK49_RS04235 5d1ca278e1dd0caa1d07e10bdf8d62b7 363 Gene3D G3DSA:1.10.443.10 167 348 3.4E-37 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 BWK49_RS04235 5d1ca278e1dd0caa1d07e10bdf8d62b7 363 Pfam PF00589 Phage integrase family 186 340 6.1E-21 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 BWK49_RS04235 5d1ca278e1dd0caa1d07e10bdf8d62b7 363 SUPERFAMILY SSF56349 62 347 1.03E-52 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 BWK49_RS04235 5d1ca278e1dd0caa1d07e10bdf8d62b7 363 Gene3D G3DSA:1.10.150.130 64 159 6.7E-12 T 06-07-2017 IPR023109 Integrase/recombinase, N-terminal BWK49_RS27500 c521e567770642667382caa998ba0771 303 SUPERFAMILY SSF48150 104 280 1.64E-30 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 BWK49_RS27500 c521e567770642667382caa998ba0771 303 Gene3D G3DSA:1.10.340.30 118 233 7.0E-22 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 BWK49_RS09130 580809a26daeaa461fee94adb9d803d2 260 Pfam PF12706 Beta-lactamase superfamily domain 50 222 1.7E-20 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS09130 580809a26daeaa461fee94adb9d803d2 260 Gene3D G3DSA:3.60.15.10 3 252 4.1E-51 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS09130 580809a26daeaa461fee94adb9d803d2 260 SMART SM00849 20 203 0.0014 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS09130 580809a26daeaa461fee94adb9d803d2 260 SUPERFAMILY SSF56281 4 254 1.49E-46 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS14380 ce589feb64504e208c9088aecaec9c55 383 Pfam PF00296 Luciferase-like monooxygenase 3 297 9.6E-48 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS14380 ce589feb64504e208c9088aecaec9c55 383 SUPERFAMILY SSF51679 2 334 8.36E-72 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS14380 ce589feb64504e208c9088aecaec9c55 383 Gene3D G3DSA:3.20.20.30 3 334 1.1E-74 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS28500 9446c48fcde5d67cf6f1654325e13556 239 SUPERFAMILY SSF52540 4 225 8.51E-19 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS28500 9446c48fcde5d67cf6f1654325e13556 239 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 9 190 2.2E-10 T 06-07-2017 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain BWK49_RS28500 9446c48fcde5d67cf6f1654325e13556 239 Gene3D G3DSA:3.40.50.300 3 226 2.5E-19 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS01715 1e051682861dcf3a6e2ae35b3e00c47e 67 Gene3D G3DSA:3.30.465.10 11 44 4.0E-6 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 BWK49_RS01715 1e051682861dcf3a6e2ae35b3e00c47e 67 SUPERFAMILY SSF56176 9 46 4.85E-7 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 BWK49_RS22105 ba929dc163e3b6a1bd823a0c7f681724 371 SUPERFAMILY SSF159245 22 262 5.89E-9 T 06-07-2017 BWK49_RS25040 29c2f53786d2301fcd73dccc1109cb1d 151 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 34 117 7.9E-14 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 BWK49_RS25040 29c2f53786d2301fcd73dccc1109cb1d 151 Pfam PF04075 Domain of unknown function (DUF385) 25 114 2.8E-8 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 BWK49_RS13320 4a63c10221af7a0a37dd3fcb217f365e 351 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 11 267 3.0E-50 T 06-07-2017 IPR005693 Virulence factor Mce protein BWK49_RS13320 4a63c10221af7a0a37dd3fcb217f365e 351 Pfam PF02470 MlaD protein 36 109 1.2E-15 T 06-07-2017 IPR003399 Mce/MlaD BWK49_RS22910 91b54e47d02f71979b79ba5e8259ea6c 222 SUPERFAMILY SSF69754 26 136 1.24E-23 T 06-07-2017 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 BWK49_RS22910 91b54e47d02f71979b79ba5e8259ea6c 222 Pfam PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus 163 218 7.9E-24 T 06-07-2017 IPR032528 Sigma 54 modulation/S30EA ribosomal protein, C-terminal BWK49_RS22910 91b54e47d02f71979b79ba5e8259ea6c 222 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 26 128 1.3E-29 T 06-07-2017 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 BWK49_RS22910 91b54e47d02f71979b79ba5e8259ea6c 222 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 27 122 1.2E-19 T 06-07-2017 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 BWK49_RS22910 91b54e47d02f71979b79ba5e8259ea6c 222 Gene3D G3DSA:3.30.160.100 25 124 7.6E-27 T 06-07-2017 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 BWK49_RS02765 b09a17fac0ac11fb5a92efc52ba96bd3 53 Pfam PF13783 Domain of unknown function (DUF4177) 7 42 4.8E-6 T 06-07-2017 IPR025234 Protein of unknown function DUF4177 BWK49_RS05885 c3506fba4248704a3ce5b9c9a7e6a1bb 243 Pfam PF00117 Glutamine amidotransferase class-I 24 227 9.6E-16 T 06-07-2017 IPR017926 Glutamine amidotransferase BWK49_RS05885 c3506fba4248704a3ce5b9c9a7e6a1bb 243 Gene3D G3DSA:3.40.50.880 2 234 6.2E-42 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like BWK49_RS05885 c3506fba4248704a3ce5b9c9a7e6a1bb 243 SUPERFAMILY SSF52317 6 232 5.83E-38 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like BWK49_RS10635 bfa73c0c7cfcef166610ab4b5d218cc8 94 Pfam PF06013 Proteins of 100 residues with WXG 3 87 1.9E-13 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like BWK49_RS10635 bfa73c0c7cfcef166610ab4b5d218cc8 94 Gene3D G3DSA:1.10.287.1060 1 94 1.4E-13 T 06-07-2017 BWK49_RS10635 bfa73c0c7cfcef166610ab4b5d218cc8 94 SUPERFAMILY SSF140453 2 93 5.23E-17 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like BWK49_RS08850 a0a62626d99ef278626a628c7a49a654 176 SUPERFAMILY SSF55811 6 175 5.42E-36 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 BWK49_RS08850 a0a62626d99ef278626a628c7a49a654 176 Pfam PF00293 NUDIX domain 45 159 2.2E-9 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 BWK49_RS08850 a0a62626d99ef278626a628c7a49a654 176 Gene3D G3DSA:3.90.79.10 5 175 3.1E-40 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 BWK49_RS20180 40a32f92c22f3cd9a92407bf60c77f9f 137 Pfam PF06150 ChaB 15 69 5.9E-19 T 06-07-2017 IPR009317 ChaB BWK49_RS20180 40a32f92c22f3cd9a92407bf60c77f9f 137 SUPERFAMILY SSF140376 11 70 2.09E-17 T 06-07-2017 BWK49_RS24415 542f8ae06b4fee7ee32392a42fa3e2ea 248 Pfam PF00934 PE family 3 95 3.2E-33 T 06-07-2017 IPR000084 PE-PGRS family, N-terminal BWK49_RS24415 542f8ae06b4fee7ee32392a42fa3e2ea 248 SUPERFAMILY SSF140459 10 86 4.71E-25 T 06-07-2017 BWK49_RS09740 9f1c690b2634b924ca46b6dc6380c7a3 170 SUPERFAMILY SSF54637 13 164 1.06E-45 T 06-07-2017 IPR029069 HotDog domain BWK49_RS09740 9f1c690b2634b924ca46b6dc6380c7a3 170 Gene3D G3DSA:3.10.129.10 12 164 3.6E-46 T 06-07-2017 IPR029069 HotDog domain BWK49_RS09740 9f1c690b2634b924ca46b6dc6380c7a3 170 Pfam PF01575 MaoC like domain 23 143 9.4E-29 T 06-07-2017 IPR002539 MaoC-like domain BWK49_RS02665 92a1c231b7737be1ecf8769aff3c8209 82 Pfam PF09360 Iron-binding zinc finger CDGSH type 11 56 1.6E-14 T 06-07-2017 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 BWK49_RS02665 92a1c231b7737be1ecf8769aff3c8209 82 SMART SM00704 17 61 4.0E-7 T 06-07-2017 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 BWK49_RS26230 bd3a542addbd92f9f67b447892127eea 676 PRINTS PR01217 Proline rich extensin signature 389 410 2.8E-9 T 06-07-2017 BWK49_RS26230 bd3a542addbd92f9f67b447892127eea 676 PRINTS PR01217 Proline rich extensin signature 444 461 2.8E-9 T 06-07-2017 BWK49_RS26230 bd3a542addbd92f9f67b447892127eea 676 PRINTS PR01217 Proline rich extensin signature 376 388 2.8E-9 T 06-07-2017 BWK49_RS26230 bd3a542addbd92f9f67b447892127eea 676 PRINTS PR01217 Proline rich extensin signature 422 438 2.8E-9 T 06-07-2017 BWK49_RS26230 bd3a542addbd92f9f67b447892127eea 676 PRINTS PR01217 Proline rich extensin signature 346 362 2.8E-9 T 06-07-2017 BWK49_RS17080 2dafa7a8d8cd18df8876134fc0bc1d60 147 Pfam PF00582 Universal stress protein family 4 144 1.6E-23 T 06-07-2017 IPR006016 UspA GO:0006950 BWK49_RS17080 2dafa7a8d8cd18df8876134fc0bc1d60 147 SUPERFAMILY SSF52402 3 144 5.36E-29 T 06-07-2017 BWK49_RS17080 2dafa7a8d8cd18df8876134fc0bc1d60 147 PRINTS PR01438 Universal stress protein signature 104 116 8.1E-18 T 06-07-2017 IPR006015 Universal stress protein A BWK49_RS17080 2dafa7a8d8cd18df8876134fc0bc1d60 147 PRINTS PR01438 Universal stress protein signature 4 22 8.1E-18 T 06-07-2017 IPR006015 Universal stress protein A BWK49_RS17080 2dafa7a8d8cd18df8876134fc0bc1d60 147 PRINTS PR01438 Universal stress protein signature 122 144 8.1E-18 T 06-07-2017 IPR006015 Universal stress protein A BWK49_RS17080 2dafa7a8d8cd18df8876134fc0bc1d60 147 Gene3D G3DSA:3.40.50.620 2 145 2.2E-34 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold BWK49_RS17700 997d74f6f5354b22a9bf83ed9f19629c 227 Gene3D G3DSA:3.40.50.150 45 170 3.4E-12 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS17700 997d74f6f5354b22a9bf83ed9f19629c 227 SUPERFAMILY SSF53335 42 169 3.7E-13 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS17700 997d74f6f5354b22a9bf83ed9f19629c 227 Pfam PF13578 Methyltransferase domain 56 167 2.2E-9 T 06-07-2017 BWK49_RS10700 db9c66f03f4d6f86608dd84107640d39 339 Gene3D G3DSA:3.30.1780.10 22 153 3.8E-25 T 06-07-2017 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 BWK49_RS10700 db9c66f03f4d6f86608dd84107640d39 339 PIRSF PIRSF001439 16 338 4.1E-51 T 06-07-2017 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 BWK49_RS10700 db9c66f03f4d6f86608dd84107640d39 339 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 24 321 1.8E-28 T 06-07-2017 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 BWK49_RS10700 db9c66f03f4d6f86608dd84107640d39 339 SUPERFAMILY SSF51735 21 338 7.61E-49 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS10700 db9c66f03f4d6f86608dd84107640d39 339 Gene3D G3DSA:3.40.50.720 154 309 1.1E-14 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS04330 ff11202c6cb13221b056707d82225e99 581 SUPERFAMILY SSF140459 126 243 1.75E-5 T 06-07-2017 BWK49_RS04330 ff11202c6cb13221b056707d82225e99 581 Pfam PF00823 PPE family 127 242 2.5E-6 T 06-07-2017 IPR000030 PPE family BWK49_RS14815 294a9331c8c7dd57db4543c7400d9c6e 147 SUPERFAMILY SSF50475 13 145 2.55E-21 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 BWK49_RS14815 294a9331c8c7dd57db4543c7400d9c6e 147 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 6 91 1.5E-9 T 06-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 BWK49_RS14815 294a9331c8c7dd57db4543c7400d9c6e 147 Gene3D G3DSA:2.30.110.10 12 145 7.4E-14 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 BWK49_RS14815 294a9331c8c7dd57db4543c7400d9c6e 147 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 8 145 5.7E-31 T 06-07-2017 IPR019920 F420-binding domain, putative BWK49_RS18705 feb44678ad4f82394ae6608b620ee502 292 Pfam PF04228 Putative neutral zinc metallopeptidase 12 286 5.4E-71 T 06-07-2017 IPR007343 Uncharacterised protein family, zinc metallopeptidase putative BWK49_RS18705 feb44678ad4f82394ae6608b620ee502 292 SUPERFAMILY SSF55486 162 242 3.48E-5 T 06-07-2017 BWK49_RS04045 140d3a742ff0fd8308f20fa7131bf0c1 199 Pfam PF02517 CAAX protease self-immunity 89 181 6.5E-15 T 06-07-2017 IPR003675 CAAX amino terminal protease GO:0016020 BWK49_RS04045 140d3a742ff0fd8308f20fa7131bf0c1 199 PIRSF PIRSF026622 1 195 6.1E-51 T 06-07-2017 IPR015837 Uncharacterised conserved protein UCP026622, CAAX protease-type BWK49_RS06570 3bacd4b736f01e755b4b4d7031b4d86c 176 SUPERFAMILY SSF55040 31 173 3.01E-55 T 06-07-2017 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 BWK49_RS06570 3bacd4b736f01e755b4b4d7031b4d86c 176 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 24 169 2.6E-63 T 06-07-2017 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 Reactome: R-HSA-947581 BWK49_RS06570 3bacd4b736f01e755b4b4d7031b4d86c 176 Pfam PF01967 MoaC family 35 168 4.0E-52 T 06-07-2017 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 BWK49_RS06570 3bacd4b736f01e755b4b4d7031b4d86c 176 Gene3D G3DSA:3.30.70.640 24 175 7.3E-63 T 06-07-2017 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 BWK49_RS06570 3bacd4b736f01e755b4b4d7031b4d86c 176 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase accessory protein [moaC]. 22 176 34.997 T 06-07-2017 IPR023046 Molybdenum cofactor biosynthesis C, bacterial-type Reactome: R-HSA-947581 BWK49_RS06985 6c1d5328772147e7f1cb888ce637ac12 508 Gene3D G3DSA:3.40.47.10 27 147 2.6E-6 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS06985 6c1d5328772147e7f1cb888ce637ac12 508 SUPERFAMILY SSF53901 282 406 1.94E-17 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS06985 6c1d5328772147e7f1cb888ce637ac12 508 SUPERFAMILY SSF53901 9 137 2.25E-6 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS09415 942df9dec5ca8c13304c465569f3cc53 126 Gene3D G3DSA:3.10.450.50 19 123 5.8E-12 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS09415 942df9dec5ca8c13304c465569f3cc53 126 SUPERFAMILY SSF54427 1 117 3.29E-14 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS09415 942df9dec5ca8c13304c465569f3cc53 126 Pfam PF12680 SnoaL-like domain 18 115 5.7E-10 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain BWK49_RS03535 6d7c120a31ac65db7b5af95a246debe4 270 SUPERFAMILY SSF52096 13 270 7.74E-76 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS03535 6d7c120a31ac65db7b5af95a246debe4 270 Pfam PF00378 Enoyl-CoA hydratase/isomerase 23 269 2.2E-56 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 BWK49_RS03535 6d7c120a31ac65db7b5af95a246debe4 270 Gene3D G3DSA:1.10.12.10 214 270 4.4E-17 T 06-07-2017 IPR014748 Crontonase, C-terminal BWK49_RS03535 6d7c120a31ac65db7b5af95a246debe4 270 Gene3D G3DSA:3.90.226.10 13 209 9.5E-60 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS05640 73b71deb8826e0579b2dda21974e2e68 138 Pfam PF01850 PIN domain 2 124 6.5E-12 T 06-07-2017 IPR002716 PIN domain BWK49_RS05640 73b71deb8826e0579b2dda21974e2e68 138 Gene3D G3DSA:3.40.50.1010 1 130 1.3E-17 T 06-07-2017 IPR029060 PIN domain-like BWK49_RS05640 73b71deb8826e0579b2dda21974e2e68 138 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 136 10.296 T 06-07-2017 IPR022907 VapC family GO:0004540 BWK49_RS05640 73b71deb8826e0579b2dda21974e2e68 138 SUPERFAMILY SSF88723 1 137 1.91E-26 T 06-07-2017 IPR029060 PIN domain-like BWK49_RS26365 217729ad35c86e7957cb6724c34bc2c1 164 Gene3D G3DSA:3.10.450.50 12 140 7.9E-30 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS26365 217729ad35c86e7957cb6724c34bc2c1 164 Pfam PF13577 SnoaL-like domain 11 134 2.3E-28 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain BWK49_RS26365 217729ad35c86e7957cb6724c34bc2c1 164 SUPERFAMILY SSF54427 7 147 1.01E-35 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS01775 bcd9ac2dffd9e6899275036ddbfd5281 188 Pfam PF00775 Dioxygenase 30 157 8.1E-16 T 06-07-2017 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 BWK49_RS01775 bcd9ac2dffd9e6899275036ddbfd5281 188 TIGRFAM TIGR02423 protocat_alph: protocatechuate 3,4-dioxygenase, alpha subunit 7 182 4.8E-51 T 06-07-2017 IPR012786 Protocatechuate 3,4-dioxygenase, alpha subunit GO:0005506|GO:0018578|GO:0019439|GO:0055114 KEGG: 00362+1.13.11.3|KEGG: 00624+1.13.11.3 BWK49_RS01775 bcd9ac2dffd9e6899275036ddbfd5281 188 SUPERFAMILY SSF49482 4 181 1.96E-40 T 06-07-2017 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 BWK49_RS01775 bcd9ac2dffd9e6899275036ddbfd5281 188 Gene3D G3DSA:2.60.130.10 6 181 2.0E-52 T 06-07-2017 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 BWK49_RS27310 04be4faa823a4a59a0dd49236413422e 506 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 172 196 4.1E-7 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 BWK49_RS27310 04be4faa823a4a59a0dd49236413422e 506 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 10 32 4.1E-7 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 BWK49_RS27310 04be4faa823a4a59a0dd49236413422e 506 SUPERFAMILY SSF51905 297 415 1.73E-54 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS27310 04be4faa823a4a59a0dd49236413422e 506 SUPERFAMILY SSF51905 11 230 1.73E-54 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS27310 04be4faa823a4a59a0dd49236413422e 506 Gene3D G3DSA:3.50.50.60 3 212 3.6E-55 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS27310 04be4faa823a4a59a0dd49236413422e 506 Gene3D G3DSA:3.50.50.60 308 486 1.0E-16 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS27310 04be4faa823a4a59a0dd49236413422e 506 Pfam PF00743 Flavin-binding monooxygenase-like 11 344 1.1E-14 T 06-07-2017 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 BWK49_RS17215 3484c89887379bc2551d619a0ff3a1a4 490 PIRSF PIRSF006446 1 487 6.0E-124 T 06-07-2017 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0016020 BWK49_RS17215 3484c89887379bc2551d619a0ff3a1a4 490 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 6 465 2.5E-157 T 06-07-2017 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0016020 BWK49_RS14675 b1b26ba0a752e1f4a38a8681604dc194 303 SUPERFAMILY SSF53335 23 287 1.89E-64 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS14675 b1b26ba0a752e1f4a38a8681604dc194 303 Gene3D G3DSA:3.40.50.150 22 206 5.9E-13 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS14675 b1b26ba0a752e1f4a38a8681604dc194 303 Pfam PF04072 Leucine carboxyl methyltransferase 27 202 3.2E-55 T 06-07-2017 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 BWK49_RS14675 b1b26ba0a752e1f4a38a8681604dc194 303 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 25 280 2.4E-81 T 06-07-2017 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 BWK49_RS18915 e80694b7ca76f698ade88bb29dc17b26 191 SUPERFAMILY SSF54197 53 189 1.18E-37 T 06-07-2017 IPR011146 HIT-like domain GO:0003824 BWK49_RS18915 e80694b7ca76f698ade88bb29dc17b26 191 Pfam PF01230 HIT domain 64 155 6.8E-16 T 06-07-2017 IPR001310 Histidine triad (HIT) protein BWK49_RS18915 e80694b7ca76f698ade88bb29dc17b26 191 Gene3D G3DSA:3.30.428.10 52 189 1.6E-40 T 06-07-2017 IPR011146 HIT-like domain GO:0003824 BWK49_RS02890 e729a452417bf52a09da2a8a59ca2d2d 266 Pfam PF00482 Type II secretion system (T2SS), protein F 98 220 2.1E-8 T 06-07-2017 IPR018076 Type II secretion system F domain BWK49_RS03425 07ffdb5ce9222394144ce1754e241195 133 SUPERFAMILY SSF54637 6 126 3.21E-16 T 06-07-2017 IPR029069 HotDog domain BWK49_RS03425 07ffdb5ce9222394144ce1754e241195 133 Gene3D G3DSA:3.10.129.10 6 124 3.3E-15 T 06-07-2017 IPR029069 HotDog domain BWK49_RS21740 505608ebc3326d5c061b1da6a2920e51 285 SUPERFAMILY SSF51679 20 279 1.31E-54 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS21740 505608ebc3326d5c061b1da6a2920e51 285 Pfam PF00296 Luciferase-like monooxygenase 8 216 5.7E-44 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS21740 505608ebc3326d5c061b1da6a2920e51 285 Gene3D G3DSA:3.20.20.30 21 279 3.8E-60 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS21740 505608ebc3326d5c061b1da6a2920e51 285 TIGRFAM TIGR03619 F420_Rv2161c: probable F420-dependent oxidoreductase, Rv2161c family 31 259 2.5E-63 T 06-07-2017 IPR019921 Luciferase-like, F420-dependent oxidoreductase, Rv2161c, predicted BWK49_RS27570 c51169e640b2f18c0d592e572ab8ef17 352 Pfam PF00296 Luciferase-like monooxygenase 12 321 2.6E-76 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS27570 c51169e640b2f18c0d592e572ab8ef17 352 Gene3D G3DSA:3.20.20.30 13 344 1.1E-70 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS27570 c51169e640b2f18c0d592e572ab8ef17 352 SUPERFAMILY SSF51679 13 346 7.85E-65 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS27980 f1a507c7bfac27ff04ffb480d31bb232 432 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 374 383 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 BWK49_RS27980 f1a507c7bfac27ff04ffb480d31bb232 432 PRINTS PR00359 B-class P450 signature 306 317 2.7E-40 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS27980 f1a507c7bfac27ff04ffb480d31bb232 432 PRINTS PR00359 B-class P450 signature 180 195 2.7E-40 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS27980 f1a507c7bfac27ff04ffb480d31bb232 432 PRINTS PR00359 B-class P450 signature 163 179 2.7E-40 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS27980 f1a507c7bfac27ff04ffb480d31bb232 432 PRINTS PR00359 B-class P450 signature 372 381 2.7E-40 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS27980 f1a507c7bfac27ff04ffb480d31bb232 432 PRINTS PR00359 B-class P450 signature 351 366 2.7E-40 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS27980 f1a507c7bfac27ff04ffb480d31bb232 432 PRINTS PR00359 B-class P450 signature 117 128 2.7E-40 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS27980 f1a507c7bfac27ff04ffb480d31bb232 432 PRINTS PR00359 B-class P450 signature 323 350 2.7E-40 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS27980 f1a507c7bfac27ff04ffb480d31bb232 432 PRINTS PR00359 B-class P450 signature 381 392 2.7E-40 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS27980 f1a507c7bfac27ff04ffb480d31bb232 432 SUPERFAMILY SSF48264 52 431 7.33E-86 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS27980 f1a507c7bfac27ff04ffb480d31bb232 432 Pfam PF00067 Cytochrome P450 251 401 1.0E-23 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS27980 f1a507c7bfac27ff04ffb480d31bb232 432 Gene3D G3DSA:1.10.630.10 45 431 6.1E-107 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS27980 f1a507c7bfac27ff04ffb480d31bb232 432 PRINTS PR00385 P450 superfamily signature 306 317 3.3E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS27980 f1a507c7bfac27ff04ffb480d31bb232 432 PRINTS PR00385 P450 superfamily signature 372 381 3.3E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS27980 f1a507c7bfac27ff04ffb480d31bb232 432 PRINTS PR00385 P450 superfamily signature 271 288 3.3E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS27980 f1a507c7bfac27ff04ffb480d31bb232 432 PRINTS PR00385 P450 superfamily signature 381 392 3.3E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS20625 8731d87894353e4a971818f23c2d9b8f 94 Pfam PF06013 Proteins of 100 residues with WXG 3 87 6.7E-13 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like BWK49_RS20625 8731d87894353e4a971818f23c2d9b8f 94 Gene3D G3DSA:1.10.287.1060 1 94 2.8E-13 T 06-07-2017 BWK49_RS20625 8731d87894353e4a971818f23c2d9b8f 94 SUPERFAMILY SSF140453 2 93 2.35E-16 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like BWK49_RS13120 047b67a6681b43a77eedbe02d7c68ab1 214 Hamap MF_01197 Cell division protein SepF [sepF]. 1 205 21.303 T 06-07-2017 IPR023052 Cell division protein SepF GO:0090529 BWK49_RS13120 047b67a6681b43a77eedbe02d7c68ab1 214 Pfam PF04472 Protein of unknown function (DUF552) 126 197 2.5E-24 T 06-07-2017 IPR007561 Cell division protein SepF/SepF-related GO:0090529 BWK49_RS23170 ca7a4ef31aa50ae91daaa1c08f696392 196 SUPERFAMILY SSF54427 43 127 1.0E-8 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS23170 ca7a4ef31aa50ae91daaa1c08f696392 196 Gene3D G3DSA:3.10.450.50 39 120 2.7E-5 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS09625 206babcd52c57a2e95b194b93365442f 444 Pfam PF07687 Peptidase dimerisation domain 191 343 5.9E-18 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain BWK49_RS09625 206babcd52c57a2e95b194b93365442f 444 SUPERFAMILY SSF53187 357 444 4.92E-58 T 06-07-2017 BWK49_RS09625 206babcd52c57a2e95b194b93365442f 444 SUPERFAMILY SSF53187 2 193 4.92E-58 T 06-07-2017 BWK49_RS09625 206babcd52c57a2e95b194b93365442f 444 Gene3D G3DSA:3.30.70.360 193 351 5.2E-40 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain BWK49_RS09625 206babcd52c57a2e95b194b93365442f 444 Pfam PF01546 Peptidase family M20/M25/M40 82 433 1.7E-35 T 06-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 BWK49_RS09625 206babcd52c57a2e95b194b93365442f 444 Gene3D G3DSA:3.40.630.10 5 187 8.0E-59 T 06-07-2017 BWK49_RS09625 206babcd52c57a2e95b194b93365442f 444 Gene3D G3DSA:3.40.630.10 356 444 8.0E-59 T 06-07-2017 BWK49_RS03610 008e3d7639d4877863eb0b7317577c10 351 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 17 299 6.8E-81 T 06-07-2017 IPR005693 Virulence factor Mce protein BWK49_RS03610 008e3d7639d4877863eb0b7317577c10 351 Pfam PF02470 MlaD protein 44 119 4.9E-17 T 06-07-2017 IPR003399 Mce/MlaD BWK49_RS06050 cf5d12bb75416105c611d1aaa2fa6696 89 Pfam PF13828 Domain of unknown function (DUF4190) 12 76 7.9E-12 T 06-07-2017 IPR025241 Domain of unknown function DUF4190 BWK49_RS24545 669cb43f78e8a7c1abd7a35dd791ca4f 194 SUPERFAMILY SSF109854 2 164 5.65E-35 T 06-07-2017 BWK49_RS24545 669cb43f78e8a7c1abd7a35dd791ca4f 194 Pfam PF04978 Protein of unknown function (DUF664) 8 165 1.2E-41 T 06-07-2017 IPR007061 Protein of unknown function DUF664 BWK49_RS24545 669cb43f78e8a7c1abd7a35dd791ca4f 194 Gene3D G3DSA:1.20.120.450 2 168 1.6E-40 T 06-07-2017 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase BWK49_RS14605 0052c4b81fd5ddb8da80643d30c92e47 327 SUPERFAMILY SSF51412 5 322 7.48E-54 T 06-07-2017 BWK49_RS14605 0052c4b81fd5ddb8da80643d30c92e47 327 Gene3D G3DSA:3.20.20.70 5 311 1.3E-54 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 BWK49_RS14605 0052c4b81fd5ddb8da80643d30c92e47 327 Pfam PF03060 Nitronate monooxygenase 8 61 4.0E-9 T 06-07-2017 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 BWK49_RS14605 0052c4b81fd5ddb8da80643d30c92e47 327 Pfam PF03060 Nitronate monooxygenase 85 316 3.4E-28 T 06-07-2017 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 BWK49_RS09565 e5f5caadb66b674cd28b0f9e459765b3 176 Gene3D G3DSA:3.10.129.10 14 170 4.9E-21 T 06-07-2017 IPR029069 HotDog domain BWK49_RS09565 e5f5caadb66b674cd28b0f9e459765b3 176 SUPERFAMILY SSF54637 13 172 1.17E-20 T 06-07-2017 IPR029069 HotDog domain BWK49_RS09565 e5f5caadb66b674cd28b0f9e459765b3 176 Pfam PF13452 N-terminal half of MaoC dehydratase 20 162 4.7E-18 T 06-07-2017 BWK49_RS01720 6d0782254e97cf45cc7743ead4821d1c 367 Pfam PF02371 Transposase IS116/IS110/IS902 family 230 312 6.7E-17 T 06-07-2017 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 BWK49_RS01720 6d0782254e97cf45cc7743ead4821d1c 367 Pfam PF01548 Transposase 15 157 1.2E-12 T 06-07-2017 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 BWK49_RS01605 6d0782254e97cf45cc7743ead4821d1c 367 Pfam PF02371 Transposase IS116/IS110/IS902 family 230 312 6.7E-17 T 06-07-2017 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 BWK49_RS01605 6d0782254e97cf45cc7743ead4821d1c 367 Pfam PF01548 Transposase 15 157 1.2E-12 T 06-07-2017 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 BWK49_RS00670 bc71a24f307046aec0d8b962d9afb921 102 SUPERFAMILY SSF140459 7 73 2.62E-12 T 06-07-2017 BWK49_RS00670 bc71a24f307046aec0d8b962d9afb921 102 Pfam PF00934 PE family 3 92 2.1E-18 T 06-07-2017 IPR000084 PE-PGRS family, N-terminal BWK49_RS00670 bc71a24f307046aec0d8b962d9afb921 102 ProDom PD195452 PE FAMILY PRECURSOR PE-FAMILY SIGNAL PE15 PE_1 47 97 9.0E-14 T 06-07-2017 BWK49_RS27320 93c0f349aa3b827a849876d4336dc147 136 SUPERFAMILY SSF54427 4 127 4.39E-31 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS27320 93c0f349aa3b827a849876d4336dc147 136 TIGRFAM TIGR02246 TIGR02246: conserved hypothetical protein 7 116 3.7E-11 T 06-07-2017 IPR011944 Steroid delta5-4-isomerase KEGG: 00140+5.3.3.1|KEGG: 00984+5.3.3.1|MetaCyc: PWY-2582|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-699|MetaCyc: PWY-7299 BWK49_RS27320 93c0f349aa3b827a849876d4336dc147 136 Gene3D G3DSA:3.10.450.50 4 128 3.7E-29 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS27320 93c0f349aa3b827a849876d4336dc147 136 Pfam PF13577 SnoaL-like domain 8 118 3.8E-21 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain BWK49_RS11735 683abf651bcbfa5724d03de84f049855 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 62 3.2E-14 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS11735 683abf651bcbfa5724d03de84f049855 189 Gene3D G3DSA:1.10.357.10 12 169 1.3E-22 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS11735 683abf651bcbfa5724d03de84f049855 189 SUPERFAMILY SSF46689 5 83 3.79E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS11735 683abf651bcbfa5724d03de84f049855 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 1.1E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS11735 683abf651bcbfa5724d03de84f049855 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 1.1E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS12875 f75bda55de37fd446dbda5abdefe725f 139 PIRSF PIRSF017385 1 139 2.4E-50 T 06-07-2017 IPR021050 Cytochrome c oxidase subunit IV, actinobacteria GO:0004129|GO:0016021|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 BWK49_RS12875 f75bda55de37fd446dbda5abdefe725f 139 Pfam PF12270 Cytochrome c oxidase subunit IV 1 137 2.8E-50 T 06-07-2017 IPR021050 Cytochrome c oxidase subunit IV, actinobacteria GO:0004129|GO:0016021|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 BWK49_RS27365 234f3a50919e88873d0e15c964ed8c51 391 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 120 8.0E-11 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS27365 234f3a50919e88873d0e15c964ed8c51 391 Gene3D G3DSA:1.20.140.10 219 308 4.2E-6 T 06-07-2017 BWK49_RS27365 234f3a50919e88873d0e15c964ed8c51 391 SUPERFAMILY SSF47203 265 384 1.12E-6 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS27365 234f3a50919e88873d0e15c964ed8c51 391 Gene3D G3DSA:1.10.540.10 8 122 7.7E-14 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS27365 234f3a50919e88873d0e15c964ed8c51 391 SUPERFAMILY SSF56645 6 241 5.5E-53 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS27365 234f3a50919e88873d0e15c964ed8c51 391 Gene3D G3DSA:2.40.110.10 124 218 2.5E-32 T 06-07-2017 BWK49_RS27365 234f3a50919e88873d0e15c964ed8c51 391 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 124 216 1.1E-21 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 BWK49_RS09570 a79bbfd6fafe6f26560f2b9583e27371 153 SUPERFAMILY SSF54637 5 148 6.06E-26 T 06-07-2017 IPR029069 HotDog domain BWK49_RS09570 a79bbfd6fafe6f26560f2b9583e27371 153 Pfam PF01575 MaoC like domain 24 110 7.7E-11 T 06-07-2017 IPR002539 MaoC-like domain BWK49_RS09570 a79bbfd6fafe6f26560f2b9583e27371 153 Gene3D G3DSA:3.10.129.10 2 147 7.4E-25 T 06-07-2017 IPR029069 HotDog domain BWK49_RS13395 83ed981c698ad647c942e8a637462696 201 PIRSF PIRSF021573 1 200 3.0E-92 T 06-07-2017 IPR016792 Uncharacterised conserved protein UCP021573 BWK49_RS12530 476a6841ad0e041e6ec84102de9c9f7b 205 Gene3D G3DSA:3.40.50.1000 68 199 4.5E-39 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS12530 476a6841ad0e041e6ec84102de9c9f7b 205 Pfam PF13419 Haloacid dehalogenase-like hydrolase 1 177 9.3E-35 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS12530 476a6841ad0e041e6ec84102de9c9f7b 205 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 91 171 5.3E-8 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 BWK49_RS12530 476a6841ad0e041e6ec84102de9c9f7b 205 SUPERFAMILY SSF56784 1 189 2.03E-47 T 06-07-2017 IPR023214 HAD-like domain BWK49_RS12530 476a6841ad0e041e6ec84102de9c9f7b 205 Gene3D G3DSA:1.10.150.240 12 67 6.9E-21 T 06-07-2017 IPR023198 Phosphoglycolate phosphatase, domain 2 BWK49_RS10235 ccbca70b745abdb2be75e26429de56f5 267 SUPERFAMILY SSF161098 13 254 6.8E-50 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS10235 ccbca70b745abdb2be75e26429de56f5 267 TIGRFAM TIGR00969 3a0106s02: sulfate ABC transporter, permease protein 13 254 8.8E-74 T 06-07-2017 IPR005667 Sulphate ABC transporter permease protein 2 GO:0008272|GO:0015419|GO:0016020 BWK49_RS10235 ccbca70b745abdb2be75e26429de56f5 267 Gene3D G3DSA:1.10.3720.10 16 263 2.3E-47 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS10235 ccbca70b745abdb2be75e26429de56f5 267 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 71 262 7.6E-25 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS10235 ccbca70b745abdb2be75e26429de56f5 267 TIGRFAM TIGR02139 permease_CysT: sulfate ABC transporter, permease protein CysT 11 256 1.5E-79 T 06-07-2017 IPR011865 Sulphate ABC transporter, permease protein CysT GO:0008272|GO:0015116|GO:0016021 BWK49_RS17050 79b253265e7688e1db2aa711ea168514 199 Pfam PF13649 Methyltransferase domain 47 140 7.1E-17 T 06-07-2017 BWK49_RS17050 79b253265e7688e1db2aa711ea168514 199 SUPERFAMILY SSF53335 12 177 2.73E-30 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS17050 79b253265e7688e1db2aa711ea168514 199 Gene3D G3DSA:3.40.50.150 26 186 2.5E-29 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS24675 2e350decb946d41ea826a69aadfe7265 249 Gene3D G3DSA:3.40.50.150 77 232 5.9E-35 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS24675 2e350decb946d41ea826a69aadfe7265 249 Pfam PF08241 Methyltransferase domain 94 201 1.2E-20 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 BWK49_RS24675 2e350decb946d41ea826a69aadfe7265 249 SUPERFAMILY SSF53335 74 248 4.91E-35 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS00290 b00cb0b48b7a3d541a2912c00327d484 246 SUPERFAMILY SSF48008 83 197 9.15E-5 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal BWK49_RS00290 b00cb0b48b7a3d541a2912c00327d484 246 Gene3D G3DSA:1.10.10.10 9 72 1.1E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS00290 b00cb0b48b7a3d541a2912c00327d484 246 Pfam PF07729 FCD domain 84 195 9.7E-6 T 06-07-2017 IPR011711 GntR, C-terminal BWK49_RS00290 b00cb0b48b7a3d541a2912c00327d484 246 SUPERFAMILY SSF46785 10 75 7.18E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS00290 b00cb0b48b7a3d541a2912c00327d484 246 Gene3D G3DSA:1.20.120.530 75 196 1.0E-4 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal BWK49_RS00290 b00cb0b48b7a3d541a2912c00327d484 246 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 71 4.8E-11 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 BWK49_RS00290 b00cb0b48b7a3d541a2912c00327d484 246 SMART SM00345 13 71 1.7E-18 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 BWK49_RS00180 ea006d829e1a39086efc430c634178cb 109 Gene3D G3DSA:3.40.630.30 15 96 1.6E-22 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase BWK49_RS00180 ea006d829e1a39086efc430c634178cb 109 Pfam PF14542 GCN5-related N-acetyl-transferase 18 95 3.6E-23 T 06-07-2017 IPR031165 Yjdj-type Gcn5-related N-acetyltransferase BWK49_RS00180 ea006d829e1a39086efc430c634178cb 109 SUPERFAMILY SSF55729 12 98 2.13E-22 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase BWK49_RS11140 ac3eae6a688b8ac41fcba0ecaffb682a 302 Gene3D G3DSA:3.90.226.10 3 251 2.1E-53 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS11140 ac3eae6a688b8ac41fcba0ecaffb682a 302 Pfam PF00378 Enoyl-CoA hydratase/isomerase 17 76 3.3E-12 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 BWK49_RS11140 ac3eae6a688b8ac41fcba0ecaffb682a 302 Pfam PF00378 Enoyl-CoA hydratase/isomerase 107 244 3.0E-19 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 BWK49_RS11140 ac3eae6a688b8ac41fcba0ecaffb682a 302 SUPERFAMILY SSF52096 2 262 1.57E-51 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS05430 7c0c29ae15403b46bed53361e9a0f601 167 SUPERFAMILY SSF56349 2 155 2.24E-35 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 BWK49_RS05430 7c0c29ae15403b46bed53361e9a0f601 167 Pfam PF00589 Phage integrase family 2 146 9.3E-29 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 BWK49_RS05430 7c0c29ae15403b46bed53361e9a0f601 167 Gene3D G3DSA:1.10.443.10 2 154 2.3E-36 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 BWK49_RS10695 959c7e7a9487d8d015629769a228a1ff 413 SUPERFAMILY SSF53686 42 353 6.16E-63 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme BWK49_RS10695 959c7e7a9487d8d015629769a228a1ff 413 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 50 331 2.4E-43 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme BWK49_RS10695 959c7e7a9487d8d015629769a228a1ff 413 Gene3D G3DSA:3.40.50.1100 79 177 3.4E-19 T 06-07-2017 BWK49_RS10695 959c7e7a9487d8d015629769a228a1ff 413 Gene3D G3DSA:3.40.50.1100 178 345 5.2E-39 T 06-07-2017 BWK49_RS13740 0486972f2624b3f444b7bf36f5550efd 355 SUPERFAMILY SSF58113 238 353 3.79E-5 T 06-07-2017 BWK49_RS13740 0486972f2624b3f444b7bf36f5550efd 355 Pfam PF07681 DoxX 6 98 2.8E-12 T 06-07-2017 IPR032808 DoxX family BWK49_RS05080 a103b2fc875e91378994f6548afb8b74 181 Gene3D G3DSA:1.20.1290.10 25 168 3.1E-32 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 BWK49_RS05080 a103b2fc875e91378994f6548afb8b74 181 Pfam PF02627 Carboxymuconolactone decarboxylase family 33 116 1.1E-15 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 BWK49_RS05080 a103b2fc875e91378994f6548afb8b74 181 SUPERFAMILY SSF69118 25 168 1.15E-29 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 BWK49_RS24760 84a1356e324a23d5fd490e12438c94d9 416 Gene3D G3DSA:1.10.630.10 7 408 1.8E-112 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS24760 84a1356e324a23d5fd490e12438c94d9 416 SUPERFAMILY SSF48264 6 408 8.51E-81 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS24760 84a1356e324a23d5fd490e12438c94d9 416 Pfam PF00067 Cytochrome P450 287 375 6.5E-12 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS24760 84a1356e324a23d5fd490e12438c94d9 416 PRINTS PR00359 B-class P450 signature 329 344 8.4E-47 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS24760 84a1356e324a23d5fd490e12438c94d9 416 PRINTS PR00359 B-class P450 signature 165 180 8.4E-47 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS24760 84a1356e324a23d5fd490e12438c94d9 416 PRINTS PR00359 B-class P450 signature 301 328 8.4E-47 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS24760 84a1356e324a23d5fd490e12438c94d9 416 PRINTS PR00359 B-class P450 signature 102 113 8.4E-47 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS24760 84a1356e324a23d5fd490e12438c94d9 416 PRINTS PR00359 B-class P450 signature 148 164 8.4E-47 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS24760 84a1356e324a23d5fd490e12438c94d9 416 PRINTS PR00359 B-class P450 signature 351 360 8.4E-47 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS24760 84a1356e324a23d5fd490e12438c94d9 416 PRINTS PR00359 B-class P450 signature 284 295 8.4E-47 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS24760 84a1356e324a23d5fd490e12438c94d9 416 PRINTS PR00359 B-class P450 signature 360 371 8.4E-47 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS24760 84a1356e324a23d5fd490e12438c94d9 416 PRINTS PR00359 B-class P450 signature 205 227 8.4E-47 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS15655 01edf43ec328f553ab257bdf4daad448 136 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 57 121 1.7E-17 T 06-07-2017 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal BWK49_RS15655 01edf43ec328f553ab257bdf4daad448 136 SUPERFAMILY SSF50249 9 129 4.8E-25 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS06070 6b640afbe5b9ea0ffd19ce6c16d3fe60 405 SUPERFAMILY SSF51556 51 362 9.95E-91 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS06070 6b640afbe5b9ea0ffd19ce6c16d3fe60 405 SUPERFAMILY SSF51338 362 401 3.6E-11 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 BWK49_RS06070 6b640afbe5b9ea0ffd19ce6c16d3fe60 405 SUPERFAMILY SSF51338 3 50 3.6E-11 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 BWK49_RS06070 6b640afbe5b9ea0ffd19ce6c16d3fe60 405 Gene3D G3DSA:2.30.40.10 349 371 2.5E-4 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 BWK49_RS06070 6b640afbe5b9ea0ffd19ce6c16d3fe60 405 Gene3D G3DSA:3.20.20.140 53 348 2.1E-87 T 06-07-2017 BWK49_RS06070 6b640afbe5b9ea0ffd19ce6c16d3fe60 405 Gene3D G3DSA:2.30.40.10 2 52 1.8E-22 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 BWK49_RS06070 6b640afbe5b9ea0ffd19ce6c16d3fe60 405 Gene3D G3DSA:2.30.40.10 372 401 1.8E-22 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 BWK49_RS06070 6b640afbe5b9ea0ffd19ce6c16d3fe60 405 Pfam PF01979 Amidohydrolase family 47 398 1.2E-32 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 BWK49_RS01635 3ca30d65971186c3e232742e40ff8abf 171 Pfam PF00866 Ring hydroxylating beta subunit 20 164 7.3E-31 T 06-07-2017 IPR000391 Ring-hydroxylating dioxygenase beta subunit GO:0003824|GO:0006725|GO:0055114 BWK49_RS01635 3ca30d65971186c3e232742e40ff8abf 171 SUPERFAMILY SSF54427 5 168 8.14E-36 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS01635 3ca30d65971186c3e232742e40ff8abf 171 Gene3D G3DSA:3.10.450.50 5 171 2.2E-45 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS10160 c752e4b4e0435145a99d937f6cd7b881 317 SUPERFAMILY SSF52540 53 173 3.35E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS10160 c752e4b4e0435145a99d937f6cd7b881 317 Pfam PF06144 DNA polymerase III, delta subunit 2 166 4.6E-7 T 06-07-2017 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 BWK49_RS10160 c752e4b4e0435145a99d937f6cd7b881 317 Gene3D G3DSA:1.10.8.60 130 209 6.2E-6 T 06-07-2017 BWK49_RS10160 c752e4b4e0435145a99d937f6cd7b881 317 SUPERFAMILY SSF48019 194 309 8.5E-11 T 06-07-2017 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 BWK49_RS10160 c752e4b4e0435145a99d937f6cd7b881 317 Gene3D G3DSA:3.40.50.300 2 97 1.1E-6 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS27790 8b745aec5707a23863ab3e5bbe82eafe 613 Gene3D G3DSA:3.50.50.60 55 248 1.7E-61 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS27790 8b745aec5707a23863ab3e5bbe82eafe 613 Gene3D G3DSA:3.50.50.60 492 573 1.7E-61 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS27790 8b745aec5707a23863ab3e5bbe82eafe 613 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 70 92 1.9E-5 T 06-07-2017 BWK49_RS27790 8b745aec5707a23863ab3e5bbe82eafe 613 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 247 272 1.9E-5 T 06-07-2017 BWK49_RS27790 8b745aec5707a23863ab3e5bbe82eafe 613 Gene3D G3DSA:3.50.50.60 249 285 3.6E-5 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS27790 8b745aec5707a23863ab3e5bbe82eafe 613 Gene3D G3DSA:3.50.50.60 397 446 3.6E-5 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS27790 8b745aec5707a23863ab3e5bbe82eafe 613 SUPERFAMILY SSF51905 70 302 9.2E-46 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS27790 8b745aec5707a23863ab3e5bbe82eafe 613 SUPERFAMILY SSF51905 401 529 9.2E-46 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS27790 8b745aec5707a23863ab3e5bbe82eafe 613 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 73 282 5.2E-10 T 06-07-2017 BWK49_RS08195 c6a0681954e215fb2bba393fc288b055 147 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 6 90 1.1E-16 T 06-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 BWK49_RS08195 c6a0681954e215fb2bba393fc288b055 147 SUPERFAMILY SSF50475 6 142 1.72E-35 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 BWK49_RS08195 c6a0681954e215fb2bba393fc288b055 147 Gene3D G3DSA:2.30.110.10 6 142 4.0E-24 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 BWK49_RS08195 c6a0681954e215fb2bba393fc288b055 147 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 11 141 3.1E-39 T 06-07-2017 IPR019920 F420-binding domain, putative BWK49_RS13130 8155cbee63b6acaa73dd5b53f2280d11 265 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 3 39 3.6E-15 T 06-07-2017 IPR019933 DivIVA domain BWK49_RS13130 8155cbee63b6acaa73dd5b53f2280d11 265 SUPERFAMILY SSF58113 114 242 1.57E-6 T 06-07-2017 BWK49_RS13130 8155cbee63b6acaa73dd5b53f2280d11 265 Pfam PF05103 DivIVA protein 3 61 3.8E-12 T 06-07-2017 IPR007793 DivIVA family BWK49_RS02735 28276505b0dc8644e8e0e7b2079719ac 346 Gene3D G3DSA:3.40.50.1100 135 327 8.3E-39 T 06-07-2017 BWK49_RS02735 28276505b0dc8644e8e0e7b2079719ac 346 SUPERFAMILY SSF53686 12 326 1.24E-70 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme BWK49_RS02735 28276505b0dc8644e8e0e7b2079719ac 346 Gene3D G3DSA:3.40.50.1100 40 134 1.4E-24 T 06-07-2017 BWK49_RS02735 28276505b0dc8644e8e0e7b2079719ac 346 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 24 305 8.6E-50 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme BWK49_RS01655 921868689352db0f33552de86c1c0709 77 Gene3D G3DSA:3.30.420.10 2 62 4.9E-7 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS01655 921868689352db0f33552de86c1c0709 77 SUPERFAMILY SSF53098 2 67 2.28E-6 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS01655 921868689352db0f33552de86c1c0709 77 Pfam PF13683 Integrase core domain 1 62 8.1E-8 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 BWK49_RS19445 f14c221079d3a489200fed9ba72536a7 333 PIRSF PIRSF035875 1 303 2.0E-58 T 06-07-2017 IPR017039 Virulence factor BrkB BWK49_RS19445 f14c221079d3a489200fed9ba72536a7 333 Pfam PF03631 Virulence factor BrkB 26 283 7.3E-44 T 06-07-2017 IPR017039 Virulence factor BrkB BWK49_RS27555 a805187cdba19a69ebc7820af01c14ca 414 Gene3D G3DSA:3.40.50.300 193 372 2.3E-11 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS27555 a805187cdba19a69ebc7820af01c14ca 414 Gene3D G3DSA:3.40.50.300 117 156 2.3E-11 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS27555 a805187cdba19a69ebc7820af01c14ca 414 Pfam PF13469 Sulfotransferase family 118 366 9.0E-36 T 06-07-2017 BWK49_RS27555 a805187cdba19a69ebc7820af01c14ca 414 SUPERFAMILY SSF52540 90 166 1.48E-33 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS27555 a805187cdba19a69ebc7820af01c14ca 414 SUPERFAMILY SSF52540 240 396 1.48E-33 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS20830 52392b3ab0ecd74635901914735265ac 194 Pfam PF12028 Protein of unknown function (DUF3515) 28 187 2.2E-57 T 06-07-2017 IPR021903 Protein of unknown function DUF3515 BWK49_RS04335 9b9cb42ae0c687425509c2bc5a70569a 128 Gene3D G3DSA:3.30.1310.10 18 100 1.6E-4 T 06-07-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family BWK49_RS04335 9b9cb42ae0c687425509c2bc5a70569a 128 ProDom PD071857 MB0031 RV0030/MT0034 11 103 0.001 T 06-07-2017 IPR024296 Protein of unknown function DUF2710 BWK49_RS04335 9b9cb42ae0c687425509c2bc5a70569a 128 Pfam PF02575 YbaB/EbfC DNA-binding family 22 100 7.5E-7 T 06-07-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family BWK49_RS07130 54d2152a9e65c97bcdd3be5682754fc3 203 Pfam PF13302 Acetyltransferase (GNAT) domain 15 158 1.5E-12 T 06-07-2017 IPR000182 GNAT domain GO:0008080 BWK49_RS07130 54d2152a9e65c97bcdd3be5682754fc3 203 Gene3D G3DSA:3.40.630.30 6 188 1.0E-46 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase BWK49_RS07130 54d2152a9e65c97bcdd3be5682754fc3 203 SUPERFAMILY SSF55729 13 181 7.28E-37 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase BWK49_RS03505 e490db74984aae9a6b0ca5c0ade2ca97 398 Gene3D G3DSA:3.40.47.10 199 225 1.9E-15 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS03505 e490db74984aae9a6b0ca5c0ade2ca97 398 Gene3D G3DSA:3.40.47.10 23 121 1.9E-15 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS03505 e490db74984aae9a6b0ca5c0ade2ca97 398 SUPERFAMILY SSF53901 236 377 1.66E-18 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS03505 e490db74984aae9a6b0ca5c0ade2ca97 398 SUPERFAMILY SSF53901 14 229 9.4E-24 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS03505 e490db74984aae9a6b0ca5c0ade2ca97 398 Gene3D G3DSA:3.40.47.10 262 377 4.5E-8 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS20305 34cf70199acb8757ac28aa10e7cd04c5 173 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 2 77 22.628 T 06-07-2017 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS20305 34cf70199acb8757ac28aa10e7cd04c5 173 SUPERFAMILY SSF54565 2 96 1.14E-31 T 06-07-2017 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS20305 34cf70199acb8757ac28aa10e7cd04c5 173 Pfam PF00886 Ribosomal protein S16 9 67 3.7E-22 T 06-07-2017 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS20305 34cf70199acb8757ac28aa10e7cd04c5 173 ProSitePatterns PS00732 Ribosomal protein S16 signature. 3 12 - T 06-07-2017 IPR020592 Ribosomal protein S16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS20305 34cf70199acb8757ac28aa10e7cd04c5 173 TIGRFAM TIGR00002 S16: ribosomal protein bS16 3 79 1.3E-30 T 06-07-2017 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS20305 34cf70199acb8757ac28aa10e7cd04c5 173 Gene3D G3DSA:3.30.1320.10 2 83 1.2E-30 T 06-07-2017 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS25725 eb0170f75614d028c4a29ea5ee1fdb7d 157 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 70 155 5.2E-13 T 06-07-2017 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain BWK49_RS11225 a4b46854931207d815c60580995e587a 140 Gene3D G3DSA:2.60.120.10 47 132 1.3E-9 T 06-07-2017 IPR014710 RmlC-like jelly roll fold BWK49_RS11225 a4b46854931207d815c60580995e587a 140 SUPERFAMILY SSF51182 57 134 2.12E-10 T 06-07-2017 IPR011051 RmlC-like cupin domain BWK49_RS25625 ea82b738e66eb98e28d8f66f3442ffef 230 SUPERFAMILY SSF55920 13 226 2.22E-25 T 06-07-2017 IPR000994 Peptidase M24, structural domain BWK49_RS25625 ea82b738e66eb98e28d8f66f3442ffef 230 Pfam PF00557 Metallopeptidase family M24 17 174 4.4E-18 T 06-07-2017 IPR000994 Peptidase M24, structural domain BWK49_RS25625 ea82b738e66eb98e28d8f66f3442ffef 230 Gene3D G3DSA:3.90.230.10 9 195 3.8E-18 T 06-07-2017 IPR000994 Peptidase M24, structural domain BWK49_RS15110 16489a67e530ebbb568f476cd2380a32 303 Pfam PF05949 Bacterial protein of unknown function (DUF881) 145 299 1.2E-33 T 06-07-2017 IPR010273 Protein of unknown function DUF881 BWK49_RS04275 4340c7fd4d74cd2a85f21b30b99d1f01 140 Pfam PF02467 Transcription factor WhiB 15 66 9.6E-10 T 06-07-2017 IPR003482 Transcription factor WhiB BWK49_RS25555 e888a3913ec857bb448319e950a49e32 322 TIGRFAM TIGR04171 RNR_1b_NrdF: ribonucleoside-diphosphate reductase, class 1b, beta subunit 9 322 2.9E-136 T 06-07-2017 IPR026494 Ribonucleoside reductase subunit beta, NrdF GO:0005971|GO:0009263 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 BWK49_RS25555 e888a3913ec857bb448319e950a49e32 322 Pfam PF00268 Ribonucleotide reductase, small chain 12 277 1.4E-81 T 06-07-2017 IPR000358 Ribonucleotide reductase small subunit GO:0009186|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 BWK49_RS25555 e888a3913ec857bb448319e950a49e32 322 Gene3D G3DSA:1.10.620.20 8 278 1.3E-85 T 06-07-2017 IPR012348 Ribonucleotide reductase-related GO:0016491|GO:0055114 Reactome: R-HSA-499943 BWK49_RS25555 e888a3913ec857bb448319e950a49e32 322 ProSitePatterns PS00368 Ribonucleotide reductase small subunit signature. 100 116 - T 06-07-2017 IPR030475 Ribonucleotide reductase small subunit, acitve site KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 BWK49_RS25555 e888a3913ec857bb448319e950a49e32 322 SUPERFAMILY SSF47240 8 322 4.33E-99 T 06-07-2017 IPR009078 Ferritin-like superfamily BWK49_RS25555 e888a3913ec857bb448319e950a49e32 322 PIRSF PIRSF000355 1 319 1.9E-74 T 06-07-2017 IPR000358 Ribonucleotide reductase small subunit GO:0009186|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 BWK49_RS03985 01393c808912318b2de211efb03fd31b 293 Pfam PF04248 Domain of unknown function (DUF427) 165 249 1.1E-20 T 06-07-2017 IPR007361 Domain of unknown function DUF427 BWK49_RS03985 01393c808912318b2de211efb03fd31b 293 Pfam PF04248 Domain of unknown function (DUF427) 38 129 9.1E-14 T 06-07-2017 IPR007361 Domain of unknown function DUF427 BWK49_RS08765 139ee4508f9ba4c847a506cf1d90f9f4 873 SUPERFAMILY SSF52540 663 703 4.11E-17 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS08765 139ee4508f9ba4c847a506cf1d90f9f4 873 SUPERFAMILY SSF52540 2 136 4.11E-17 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS08765 139ee4508f9ba4c847a506cf1d90f9f4 873 SUPERFAMILY SSF52540 740 862 4.11E-17 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS08765 139ee4508f9ba4c847a506cf1d90f9f4 873 Gene3D G3DSA:3.40.50.300 386 387 5.8E-16 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS08765 139ee4508f9ba4c847a506cf1d90f9f4 873 Gene3D G3DSA:3.40.50.300 2 158 5.8E-16 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS08765 139ee4508f9ba4c847a506cf1d90f9f4 873 Gene3D G3DSA:3.40.50.300 774 859 5.8E-16 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS08765 139ee4508f9ba4c847a506cf1d90f9f4 873 Gene3D G3DSA:3.40.50.300 617 618 5.8E-16 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS08765 139ee4508f9ba4c847a506cf1d90f9f4 873 Pfam PF13175 AAA ATPase domain 2 59 3.0E-10 T 06-07-2017 BWK49_RS03945 e55b3e29b13c817541954d54bd146c2e 271 SMART SM00563 53 172 4.3E-4 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 BWK49_RS03945 e55b3e29b13c817541954d54bd146c2e 271 PIRSF PIRSF016753 4 271 8.3E-75 T 06-07-2017 IPR016676 Phospholipid/glycerol acyltransferase, predicted BWK49_RS03945 e55b3e29b13c817541954d54bd146c2e 271 SUPERFAMILY SSF69593 35 175 9.02E-13 T 06-07-2017 BWK49_RS03945 e55b3e29b13c817541954d54bd146c2e 271 SUPERFAMILY SSF69593 211 261 9.02E-13 T 06-07-2017 BWK49_RS03945 e55b3e29b13c817541954d54bd146c2e 271 Pfam PF01553 Acyltransferase 39 168 1.2E-14 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 BWK49_RS17685 18994a003fdd888339d8efb06bf2f5c2 275 Gene3D G3DSA:3.40.50.720 1 182 1.8E-25 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS17685 18994a003fdd888339d8efb06bf2f5c2 275 SUPERFAMILY SSF51735 1 259 5.99E-48 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS17685 18994a003fdd888339d8efb06bf2f5c2 275 Gene3D G3DSA:3.90.25.10 183 258 5.3E-13 T 06-07-2017 BWK49_RS17685 18994a003fdd888339d8efb06bf2f5c2 275 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 220 4.7E-30 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 BWK49_RS05260 d7b3643c0082795a8874f1310f7d0741 119 Pfam PF01610 Transposase 46 104 1.0E-17 T 06-07-2017 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain BWK49_RS19975 d4a3e97f9bcd70b70d01f6046922a154 156 Pfam PF13673 Acetyltransferase (GNAT) domain 45 146 2.3E-14 T 06-07-2017 IPR000182 GNAT domain GO:0008080 BWK49_RS19975 d4a3e97f9bcd70b70d01f6046922a154 156 Gene3D G3DSA:3.40.630.30 10 147 4.4E-35 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase BWK49_RS19975 d4a3e97f9bcd70b70d01f6046922a154 156 SUPERFAMILY SSF55729 13 148 9.57E-29 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase BWK49_RS01615 9f1a8dea5db71ed3fd5b332cae95af5d 280 SUPERFAMILY SSF56529 19 273 2.29E-75 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 BWK49_RS01615 9f1a8dea5db71ed3fd5b332cae95af5d 280 Gene3D G3DSA:3.90.850.10 20 275 2.9E-82 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 BWK49_RS01615 9f1a8dea5db71ed3fd5b332cae95af5d 280 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 115 273 1.2E-10 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 BWK49_RS25375 89516913b30ac607c254f4bf8f9ac38e 177 Pfam PF10722 Putative bacterial sensory transduction regulator 10 135 3.7E-24 T 06-07-2017 IPR019660 Putative sensory transduction regulator YbjN BWK49_RS25375 89516913b30ac607c254f4bf8f9ac38e 177 Gene3D G3DSA:3.30.1460.10 9 148 2.6E-16 T 06-07-2017 BWK49_RS25375 89516913b30ac607c254f4bf8f9ac38e 177 SUPERFAMILY SSF69635 7 137 2.79E-27 T 06-07-2017 BWK49_RS27615 feccea8f891d7ba15975f69dc9a9e6b4 299 Gene3D G3DSA:1.20.1260.10 2 210 9.0E-73 T 06-07-2017 IPR012347 Ferritin-related BWK49_RS27615 feccea8f891d7ba15975f69dc9a9e6b4 299 SUPERFAMILY SSF47240 2 263 1.63E-80 T 06-07-2017 IPR009078 Ferritin-like superfamily BWK49_RS27615 feccea8f891d7ba15975f69dc9a9e6b4 299 Pfam PF05067 Manganese containing catalase 2 260 1.1E-67 T 06-07-2017 IPR007760 Manganese catalase BWK49_RS00770 e083f51ae28780b4c7e4a148ae07b202 88 Pfam PF13376 Bacteriocin-protection, YdeI or OmpD-Associated 13 70 5.8E-20 T 06-07-2017 BWK49_RS06425 37bf07b61e194c091b0055ec2cdd94b7 233 SUPERFAMILY SSF48498 88 189 6.67E-6 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS06425 37bf07b61e194c091b0055ec2cdd94b7 233 SUPERFAMILY SSF46689 5 87 7.18E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS06425 37bf07b61e194c091b0055ec2cdd94b7 233 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 5.4E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS06425 37bf07b61e194c091b0055ec2cdd94b7 233 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 5.4E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS06425 37bf07b61e194c091b0055ec2cdd94b7 233 Gene3D G3DSA:1.10.357.10 3 171 1.4E-27 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS06425 37bf07b61e194c091b0055ec2cdd94b7 233 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 64 5.5E-13 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS05300 7d714860d6c275664a8156b1210f63f4 452 Pfam PF06974 Protein of unknown function (DUF1298) 266 379 3.4E-8 T 06-07-2017 IPR009721 O-acyltransferase WSD1, C-terminal GO:0004144 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 BWK49_RS05300 7d714860d6c275664a8156b1210f63f4 452 SUPERFAMILY SSF52777 44 149 1.48E-8 T 06-07-2017 BWK49_RS05300 7d714860d6c275664a8156b1210f63f4 452 Pfam PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain 45 163 3.3E-35 T 06-07-2017 IPR004255 O-acyltransferase, WSD1, N-terminal GO:0004144|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 BWK49_RS12400 5371682b0fd50c203b530c9d67870d90 352 Gene3D G3DSA:3.40.50.150 167 347 8.0E-33 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS12400 5371682b0fd50c203b530c9d67870d90 352 SUPERFAMILY SSF53335 161 347 1.15E-31 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS12400 5371682b0fd50c203b530c9d67870d90 352 Pfam PF13847 Methyltransferase domain 171 284 8.9E-26 T 06-07-2017 IPR025714 Methyltransferase domain BWK49_RS27350 402c7bfa9b87f1288dc96b0ad0224e1f 389 Pfam PF02515 CoA-transferase family III 6 376 2.1E-114 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 BWK49_RS27350 402c7bfa9b87f1288dc96b0ad0224e1f 389 SUPERFAMILY SSF89796 1 384 1.22E-107 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS27350 402c7bfa9b87f1288dc96b0ad0224e1f 389 Gene3D G3DSA:3.30.1540.10 230 309 3.4E-23 T 06-07-2017 BWK49_RS27350 402c7bfa9b87f1288dc96b0ad0224e1f 389 Gene3D G3DSA:3.40.50.10540 310 384 1.6E-89 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS27350 402c7bfa9b87f1288dc96b0ad0224e1f 389 Gene3D G3DSA:3.40.50.10540 2 218 1.6E-89 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS28875 ba0ced76994668bab33cf2de9fbd8410 145 Pfam PF02467 Transcription factor WhiB 37 85 7.3E-11 T 06-07-2017 IPR003482 Transcription factor WhiB BWK49_RS21485 28dc15b13dddf4c1bb79f40d773f97b1 336 Pfam PF12697 Alpha/beta hydrolase family 68 315 5.1E-12 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS21485 28dc15b13dddf4c1bb79f40d773f97b1 336 Gene3D G3DSA:3.40.50.1820 54 328 2.4E-24 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS21485 28dc15b13dddf4c1bb79f40d773f97b1 336 SUPERFAMILY SSF53474 54 332 1.47E-28 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS18225 4fc0d981cad7f8ac3e96bf01801dd53f 251 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 10 233 7.4E-74 T 06-07-2017 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 BWK49_RS18225 4fc0d981cad7f8ac3e96bf01801dd53f 251 Gene3D G3DSA:3.40.50.1360 5 243 5.3E-78 T 06-07-2017 BWK49_RS18225 4fc0d981cad7f8ac3e96bf01801dd53f 251 TIGRFAM TIGR01198 pgl: 6-phosphogluconolactonase 7 243 1.1E-82 T 06-07-2017 IPR005900 6-phosphogluconolactonase, DevB-type GO:0005975|GO:0006098|GO:0017057 KEGG: 00030+3.1.1.31 BWK49_RS18225 4fc0d981cad7f8ac3e96bf01801dd53f 251 SUPERFAMILY SSF100950 5 244 4.9E-69 T 06-07-2017 BWK49_RS06945 44fa64c197d1ef1d62ab1c4fbe519557 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 8.5E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS06945 44fa64c197d1ef1d62ab1c4fbe519557 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 8.5E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS06945 44fa64c197d1ef1d62ab1c4fbe519557 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 8.5E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS06945 44fa64c197d1ef1d62ab1c4fbe519557 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 8.5E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS06945 44fa64c197d1ef1d62ab1c4fbe519557 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 8.5E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS06945 44fa64c197d1ef1d62ab1c4fbe519557 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 2.1E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS06945 44fa64c197d1ef1d62ab1c4fbe519557 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 2.1E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS06945 44fa64c197d1ef1d62ab1c4fbe519557 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 2.1E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS06945 44fa64c197d1ef1d62ab1c4fbe519557 249 Pfam PF00106 short chain dehydrogenase 5 199 3.3E-44 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS06945 44fa64c197d1ef1d62ab1c4fbe519557 249 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 BWK49_RS06945 44fa64c197d1ef1d62ab1c4fbe519557 249 SUPERFAMILY SSF51735 3 247 5.57E-52 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS06945 44fa64c197d1ef1d62ab1c4fbe519557 249 Gene3D G3DSA:3.40.50.720 6 219 2.4E-50 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS16340 4c707b80ae0bfcd3ca3b6d92408b3434 456 Gene3D G3DSA:3.50.50.60 143 240 2.1E-31 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS16340 4c707b80ae0bfcd3ca3b6d92408b3434 456 Gene3D G3DSA:3.50.50.60 391 452 2.1E-31 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS16340 4c707b80ae0bfcd3ca3b6d92408b3434 456 Gene3D G3DSA:3.50.50.60 325 338 2.1E-31 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS16340 4c707b80ae0bfcd3ca3b6d92408b3434 456 Gene3D G3DSA:3.50.50.60 4 111 2.1E-31 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS16340 4c707b80ae0bfcd3ca3b6d92408b3434 456 Pfam PF00890 FAD binding domain 6 229 7.8E-5 T 06-07-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 BWK49_RS16340 4c707b80ae0bfcd3ca3b6d92408b3434 456 SUPERFAMILY SSF51905 3 253 2.66E-28 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS16340 4c707b80ae0bfcd3ca3b6d92408b3434 456 SUPERFAMILY SSF51905 400 451 2.66E-28 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS16340 4c707b80ae0bfcd3ca3b6d92408b3434 456 Pfam PF05199 GMC oxidoreductase 394 445 4.5E-6 T 06-07-2017 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 BWK49_RS16800 646c36760fb9f400dad305ac62b12d89 84 Pfam PF13490 Putative zinc-finger 12 46 4.5E-8 T 06-07-2017 IPR027383 Putative zinc-finger BWK49_RS06140 3a21876a51105a9e8756a6e1433841d4 401 PRINTS PR00359 B-class P450 signature 273 284 7.6E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS06140 3a21876a51105a9e8756a6e1433841d4 401 PRINTS PR00359 B-class P450 signature 318 333 7.6E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS06140 3a21876a51105a9e8756a6e1433841d4 401 PRINTS PR00359 B-class P450 signature 146 161 7.6E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS06140 3a21876a51105a9e8756a6e1433841d4 401 PRINTS PR00359 B-class P450 signature 187 209 7.6E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS06140 3a21876a51105a9e8756a6e1433841d4 401 PRINTS PR00359 B-class P450 signature 341 350 7.6E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS06140 3a21876a51105a9e8756a6e1433841d4 401 PRINTS PR00359 B-class P450 signature 129 145 7.6E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS06140 3a21876a51105a9e8756a6e1433841d4 401 PRINTS PR00359 B-class P450 signature 84 95 7.6E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS06140 3a21876a51105a9e8756a6e1433841d4 401 PRINTS PR00359 B-class P450 signature 350 361 7.6E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS06140 3a21876a51105a9e8756a6e1433841d4 401 PRINTS PR00359 B-class P450 signature 290 317 7.6E-48 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS06140 3a21876a51105a9e8756a6e1433841d4 401 Gene3D G3DSA:1.10.630.10 8 399 1.8E-104 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS06140 3a21876a51105a9e8756a6e1433841d4 401 Pfam PF00067 Cytochrome P450 191 368 5.3E-19 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS06140 3a21876a51105a9e8756a6e1433841d4 401 SUPERFAMILY SSF48264 11 400 1.01E-84 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS01535 103428e9cf89c9a009c84caeb244d310 180 Gene3D G3DSA:3.10.450.50 7 179 7.0E-57 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS01535 103428e9cf89c9a009c84caeb244d310 180 SUPERFAMILY SSF54427 17 179 2.14E-42 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS01535 103428e9cf89c9a009c84caeb244d310 180 Pfam PF00866 Ring hydroxylating beta subunit 30 172 4.8E-39 T 06-07-2017 IPR000391 Ring-hydroxylating dioxygenase beta subunit GO:0003824|GO:0006725|GO:0055114 BWK49_RS00995 ce962f62a4c16f01b617c1af1e8ae187 132 SUPERFAMILY SSF47413 35 78 7.03E-5 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 BWK49_RS00995 ce962f62a4c16f01b617c1af1e8ae187 132 Gene3D G3DSA:1.10.260.40 35 119 3.9E-8 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 BWK49_RS11295 9648834a0d2414cb799a219c4183c1b5 463 Pfam PF00823 PPE family 5 161 2.7E-64 T 06-07-2017 IPR000030 PPE family BWK49_RS11295 9648834a0d2414cb799a219c4183c1b5 463 SUPERFAMILY SSF140459 2 174 1.36E-64 T 06-07-2017 BWK49_RS11295 9648834a0d2414cb799a219c4183c1b5 463 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 379 458 4.1E-11 T 06-07-2017 IPR022171 PPE family, C-terminal BWK49_RS18175 35aaefae96cd55ffea44762840bc1a7d 319 Gene3D G3DSA:3.40.50.300 10 235 9.0E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS18175 35aaefae96cd55ffea44762840bc1a7d 319 SUPERFAMILY SSF52540 13 233 1.26E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS18175 35aaefae96cd55ffea44762840bc1a7d 319 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 BWK49_RS18175 35aaefae96cd55ffea44762840bc1a7d 319 SMART SM00382 42 220 9.7E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS18175 35aaefae96cd55ffea44762840bc1a7d 319 Pfam PF00005 ABC transporter 34 172 9.9E-24 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 BWK49_RS22325 1410c6835cbf5bbecd00322d058bfe09 427 Pfam PF01757 Acyltransferase family 25 355 1.1E-16 T 06-07-2017 IPR002656 Acyltransferase 3 GO:0016747 BWK49_RS26470 b3185a2b8dd61361de6d5d0419e750b8 84 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 83 1.7E-18 T 06-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS26470 b3185a2b8dd61361de6d5d0419e750b8 84 PRINTS PR01249 Ribosomal protein L31 signature 63 81 9.9E-10 T 06-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS26470 b3185a2b8dd61361de6d5d0419e750b8 84 PRINTS PR01249 Ribosomal protein L31 signature 2 19 9.9E-10 T 06-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS26470 b3185a2b8dd61361de6d5d0419e750b8 84 ProSitePatterns PS01143 Ribosomal protein L31 signature. 52 73 - T 06-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS26470 b3185a2b8dd61361de6d5d0419e750b8 84 SUPERFAMILY SSF143800 1 82 7.85E-21 T 06-07-2017 BWK49_RS26470 b3185a2b8dd61361de6d5d0419e750b8 84 Hamap MF_00502 50S ribosomal protein L31 type B [rpmE2]. 1 84 23.32 T 06-07-2017 IPR027493 Ribosomal protein L31 type B GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS26470 b3185a2b8dd61361de6d5d0419e750b8 84 Pfam PF01197 Ribosomal protein L31 1 82 4.8E-28 T 06-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS15280 6bd98a12d463996e93199704779e60d0 57 Pfam PF00934 PE family 10 51 1.3E-8 T 06-07-2017 IPR000084 PE-PGRS family, N-terminal BWK49_RS15280 6bd98a12d463996e93199704779e60d0 57 SUPERFAMILY SSF140459 9 41 4.45E-6 T 06-07-2017 BWK49_RS28810 6685b6c56681f7742b79dc1de14ceb3d 94 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 2 70 1.2E-19 T 06-07-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM BWK49_RS28810 6685b6c56681f7742b79dc1de14ceb3d 94 SUPERFAMILY SSF143120 3 71 8.72E-20 T 06-07-2017 BWK49_RS28810 6685b6c56681f7742b79dc1de14ceb3d 94 Gene3D G3DSA:3.40.1620.10 3 48 1.2E-4 T 06-07-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM BWK49_RS28810 6685b6c56681f7742b79dc1de14ceb3d 94 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 2 54 9.5E-19 T 06-07-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM BWK49_RS28390 f9474de9ee816863c24b41436d22f322 47 Pfam PF00468 Ribosomal protein L34 5 47 1.2E-17 T 06-07-2017 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS28390 f9474de9ee816863c24b41436d22f322 47 ProSitePatterns PS00784 Ribosomal protein L34 signature. 5 24 - T 06-07-2017 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 BWK49_RS28390 f9474de9ee816863c24b41436d22f322 47 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 5 47 1.9E-16 T 06-07-2017 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS28390 f9474de9ee816863c24b41436d22f322 47 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 5 45 2.0E-14 T 06-07-2017 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS28390 f9474de9ee816863c24b41436d22f322 47 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 4 47 15.077 T 06-07-2017 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS01430 214163d6c49db24af8aa645e51a02784 484 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 10 295 3.3E-75 T 06-07-2017 IPR005693 Virulence factor Mce protein BWK49_RS01430 214163d6c49db24af8aa645e51a02784 484 Pfam PF02470 MlaD protein 41 115 9.5E-15 T 06-07-2017 IPR003399 Mce/MlaD BWK49_RS16260 75b2df7e1324014ed6254dea82e807fc 312 Pfam PF00146 NADH dehydrogenase 45 303 2.8E-44 T 06-07-2017 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS24300 2e0ac0b1a90dc5e49c1d1414f4b36b58 187 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 7 116 29.188 T 06-07-2017 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS24300 2e0ac0b1a90dc5e49c1d1414f4b36b58 187 ProSitePatterns PS00464 Ribosomal protein L22 signature. 89 113 - T 06-07-2017 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 BWK49_RS24300 2e0ac0b1a90dc5e49c1d1414f4b36b58 187 Gene3D G3DSA:3.90.470.10 9 116 2.6E-42 T 06-07-2017 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 BWK49_RS24300 2e0ac0b1a90dc5e49c1d1414f4b36b58 187 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 11 113 2.4E-50 T 06-07-2017 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 BWK49_RS24300 2e0ac0b1a90dc5e49c1d1414f4b36b58 187 SUPERFAMILY SSF54843 7 116 2.88E-41 T 06-07-2017 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 BWK49_RS24300 2e0ac0b1a90dc5e49c1d1414f4b36b58 187 Pfam PF00237 Ribosomal protein L22p/L17e 14 114 3.3E-30 T 06-07-2017 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 BWK49_RS21270 6cc77ee4d06a597ac318109b1d232e96 286 SUPERFAMILY SSF52540 17 253 2.52E-45 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS21270 6cc77ee4d06a597ac318109b1d232e96 286 Gene3D G3DSA:3.40.50.300 14 255 1.8E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS21270 6cc77ee4d06a597ac318109b1d232e96 286 Pfam PF00005 ABC transporter 39 187 6.2E-24 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 BWK49_RS21270 6cc77ee4d06a597ac318109b1d232e96 286 SMART SM00382 45 246 1.2E-7 T 06-07-2017 IPR003593 AAA+ ATPase domain BWK49_RS21715 0536a4aee7e5b8692d07b62f03e604a1 119 Pfam PF05305 Protein of unknown function (DUF732) 17 109 7.0E-16 T 06-07-2017 IPR007969 Domain of unknown function DUF732 BWK49_RS12760 96e0b96a2ab70ed107163bdf2008fc0a 140 PIRSF PIRSF021697 1 140 1.6E-61 T 06-07-2017 IPR016795 Uncharacterised conserved protein UCP021697, membrane BWK49_RS12760 96e0b96a2ab70ed107163bdf2008fc0a 140 Pfam PF06271 RDD family 25 114 3.3E-7 T 06-07-2017 IPR010432 RDD BWK49_RS12560 cffcb9c72cb525af33f899697c008c7c 280 Gene3D G3DSA:1.10.10.60 216 245 4.2E-6 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS12560 cffcb9c72cb525af33f899697c008c7c 280 SUPERFAMILY SSF46689 209 246 1.34E-5 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS12560 cffcb9c72cb525af33f899697c008c7c 280 Gene3D G3DSA:1.10.10.60 142 197 1.6E-8 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS12560 cffcb9c72cb525af33f899697c008c7c 280 Pfam PF12833 Helix-turn-helix domain 165 247 3.7E-14 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 BWK49_RS12560 cffcb9c72cb525af33f899697c008c7c 280 SMART SM00342 158 246 2.2E-12 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 BWK49_RS05135 e8d26bab6102b2c38c38bc3abd6595b1 411 ProSitePatterns PS01007 Transposases, Mutator family, signature. 233 257 - T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 BWK49_RS05135 e8d26bab6102b2c38c38bc3abd6595b1 411 Pfam PF00872 Transposase, Mutator family 7 379 1.4E-146 T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 BWK49_RS12205 231599e32c1237affe9c91a06b992a7a 108 Gene3D G3DSA:3.30.70.20 3 76 4.4E-18 T 06-07-2017 BWK49_RS12205 231599e32c1237affe9c91a06b992a7a 108 SUPERFAMILY SSF54862 3 64 2.79E-19 T 06-07-2017 BWK49_RS12205 231599e32c1237affe9c91a06b992a7a 108 PRINTS PR00354 7Fe ferredoxin signature 9 19 4.7E-18 T 06-07-2017 IPR000813 7Fe ferredoxin GO:0009055 BWK49_RS12205 231599e32c1237affe9c91a06b992a7a 108 PRINTS PR00354 7Fe ferredoxin signature 19 29 4.7E-18 T 06-07-2017 IPR000813 7Fe ferredoxin GO:0009055 BWK49_RS12205 231599e32c1237affe9c91a06b992a7a 108 PRINTS PR00354 7Fe ferredoxin signature 35 52 4.7E-18 T 06-07-2017 IPR000813 7Fe ferredoxin GO:0009055 BWK49_RS12205 231599e32c1237affe9c91a06b992a7a 108 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site BWK49_RS12205 231599e32c1237affe9c91a06b992a7a 108 Pfam PF00037 4Fe-4S binding domain 34 55 1.4E-7 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain BWK49_RS07730 e37fef738422253bd748da847c685b5b 244 Pfam PF06271 RDD family 83 228 9.9E-25 T 06-07-2017 IPR010432 RDD BWK49_RS12310 39c0f846d72083d61dfea8ec446e5de4 170 Pfam PF02627 Carboxymuconolactone decarboxylase family 33 99 4.4E-10 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 BWK49_RS12310 39c0f846d72083d61dfea8ec446e5de4 170 SUPERFAMILY SSF69118 3 169 1.65E-26 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 BWK49_RS12310 39c0f846d72083d61dfea8ec446e5de4 170 Gene3D G3DSA:1.20.1290.10 24 168 4.5E-24 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 BWK49_RS09375 ebf526865d04e246e143c1676abebf02 157 SUPERFAMILY SSF55961 7 155 3.91E-17 T 06-07-2017 BWK49_RS09375 ebf526865d04e246e143c1676abebf02 157 Gene3D G3DSA:3.30.530.20 5 111 2.5E-10 T 06-07-2017 IPR023393 START-like domain BWK49_RS09375 ebf526865d04e246e143c1676abebf02 157 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 9 141 1.7E-14 T 06-07-2017 IPR019587 Polyketide cyclase/dehydrase BWK49_RS16125 b31f18c26e9eb081d27bb3115447c82c 93 ProDom PD020015 MB2016C IRON REGULATED MB3297 RV1993C/MT2049 RV0968/MT0996 IRP10 ML0748 MB0993 1 82 6.0E-21 T 06-07-2017 IPR009963 Protein of unknown function DUF1490 BWK49_RS16125 b31f18c26e9eb081d27bb3115447c82c 93 Pfam PF07371 Protein of unknown function (DUF1490) 2 81 3.9E-37 T 06-07-2017 IPR009963 Protein of unknown function DUF1490 BWK49_RS13685 a5245368b146c4f60b71b52aae2dfe7a 360 Gene3D G3DSA:3.40.50.720 3 212 3.5E-27 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS13685 a5245368b146c4f60b71b52aae2dfe7a 360 SUPERFAMILY SSF51735 8 145 5.12E-11 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS00245 c099da3d800f24e60d186190820ad3ce 428 Pfam PF07690 Major Facilitator Superfamily 47 379 1.5E-9 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 BWK49_RS00245 c099da3d800f24e60d186190820ad3ce 428 Gene3D G3DSA:1.20.1250.20 52 204 1.8E-9 T 06-07-2017 BWK49_RS00245 c099da3d800f24e60d186190820ad3ce 428 Gene3D G3DSA:1.20.1250.20 258 420 9.7E-7 T 06-07-2017 BWK49_RS00245 c099da3d800f24e60d186190820ad3ce 428 SUPERFAMILY SSF103473 50 421 5.49E-23 T 06-07-2017 IPR020846 Major facilitator superfamily domain BWK49_RS08580 6f2e8377e59d0759e394bec39e421474 294 SUPERFAMILY SSF161098 10 284 2.71E-48 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS08580 6f2e8377e59d0759e394bec39e421474 294 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 282 1.4E-10 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS08580 6f2e8377e59d0759e394bec39e421474 294 Gene3D G3DSA:1.10.3720.10 5 279 2.3E-52 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS06275 3b8441f5972aa6e18a8073a73b2aa468 467 Pfam PF05893 Acyl-CoA reductase (LuxC) 55 456 2.2E-103 T 06-07-2017 IPR008670 Acyl-CoA reductase, LuxC GO:0003995|GO:0008218|GO:0055114 KEGG: 00073+1.2.1.50|MetaCyc: PWY-7723 BWK49_RS06275 3b8441f5972aa6e18a8073a73b2aa468 467 PIRSF PIRSF009414 42 462 1.2E-64 T 06-07-2017 IPR008670 Acyl-CoA reductase, LuxC GO:0003995|GO:0008218|GO:0055114 KEGG: 00073+1.2.1.50|MetaCyc: PWY-7723 BWK49_RS21400 4c3ecfe192b2f3b4fd0ccfa08ddc5149 397 SUPERFAMILY SSF53901 8 117 1.64E-11 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS21400 4c3ecfe192b2f3b4fd0ccfa08ddc5149 397 SUPERFAMILY SSF53901 146 243 1.64E-11 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS21400 4c3ecfe192b2f3b4fd0ccfa08ddc5149 397 Gene3D G3DSA:3.40.47.10 214 239 1.1E-5 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS21400 4c3ecfe192b2f3b4fd0ccfa08ddc5149 397 Gene3D G3DSA:3.40.47.10 10 110 1.1E-5 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS21400 4c3ecfe192b2f3b4fd0ccfa08ddc5149 397 SUPERFAMILY SSF53901 267 385 6.17E-15 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS13815 3d221aeaa33dca798be7a976f6b5e815 174 SUPERFAMILY SSF82784 7 171 7.72E-35 T 06-07-2017 IPR003718 OsmC/Ohr family BWK49_RS13815 3d221aeaa33dca798be7a976f6b5e815 174 Gene3D G3DSA:3.30.300.20 7 162 1.2E-40 T 06-07-2017 IPR015946 K homology domain-like, alpha/beta BWK49_RS13815 3d221aeaa33dca798be7a976f6b5e815 174 Pfam PF02566 OsmC-like protein 62 168 3.2E-22 T 06-07-2017 IPR003718 OsmC/Ohr family BWK49_RS23885 479bed99cc20f58d1805dccf89dd703e 297 Pfam PF14494 Domain of unknown function (DUF4436) 45 277 4.7E-95 T 06-07-2017 IPR027948 Protein of unknown function (DUF4436) BWK49_RS21225 8f8b8aff449cde2def9b9dc0c455c036 181 Pfam PF14230 Domain of unknown function (DUF4333) 19 93 6.8E-18 T 06-07-2017 IPR025637 Domain of unknown function DUF4333 BWK49_RS21225 8f8b8aff449cde2def9b9dc0c455c036 181 Pfam PF14230 Domain of unknown function (DUF4333) 104 162 4.1E-15 T 06-07-2017 IPR025637 Domain of unknown function DUF4333 BWK49_RS13440 ab1504933dcc1cb96224f7270e1462b0 92 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 1 91 22.174 T 06-07-2017 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 BWK49_RS13440 ab1504933dcc1cb96224f7270e1462b0 92 Pfam PF02416 mttA/Hcf106 family 4 53 1.9E-23 T 06-07-2017 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 BWK49_RS13440 ab1504933dcc1cb96224f7270e1462b0 92 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 3 49 1.5E-21 T 06-07-2017 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 BWK49_RS19190 970b909a92c0101f047b33195fb95a1d 121 Pfam PF13827 Domain of unknown function (DUF4189) 29 117 1.3E-9 T 06-07-2017 IPR025240 Domain of unknown function DUF4189 BWK49_RS13140 64d4b13a652349727683e205fdf480ae 224 Gene3D G3DSA:3.40.50.2020 15 74 1.1E-41 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like BWK49_RS13140 64d4b13a652349727683e205fdf480ae 224 Gene3D G3DSA:3.40.50.2020 106 215 1.1E-41 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like BWK49_RS13140 64d4b13a652349727683e205fdf480ae 224 SUPERFAMILY SSF53271 16 220 7.08E-51 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like BWK49_RS13140 64d4b13a652349727683e205fdf480ae 224 Pfam PF00156 Phosphoribosyl transferase domain 20 207 3.8E-25 T 06-07-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 BWK49_RS26735 10a291661d26faf78aae34e776580d32 64 Pfam PF11021 Protein of unknown function (DUF2613) 4 55 1.1E-9 T 06-07-2017 IPR022566 Protein of unknown function DUF2613 BWK49_RS17590 f79ccc278a9a7e5a3a30714305f64336 374 SUPERFAMILY SSF51412 114 367 5.34E-49 T 06-07-2017 BWK49_RS17590 f79ccc278a9a7e5a3a30714305f64336 374 SUPERFAMILY SSF51412 1 70 5.34E-49 T 06-07-2017 BWK49_RS17590 f79ccc278a9a7e5a3a30714305f64336 374 Gene3D G3DSA:3.20.20.70 1 79 2.4E-63 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 BWK49_RS17590 f79ccc278a9a7e5a3a30714305f64336 374 Gene3D G3DSA:3.20.20.70 124 354 2.4E-63 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 BWK49_RS17590 f79ccc278a9a7e5a3a30714305f64336 374 Pfam PF03060 Nitronate monooxygenase 22 360 3.1E-56 T 06-07-2017 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 BWK49_RS10395 825846aaf96654a69a39d1464b3e2d5a 619 Pfam PF06527 TniQ 27 164 3.1E-20 T 06-07-2017 IPR009492 TniQ BWK49_RS09260 b92128f063c8a790ce3da3551d7abd11 227 SUPERFAMILY SSF54637 27 202 7.79E-26 T 06-07-2017 IPR029069 HotDog domain BWK49_RS09260 b92128f063c8a790ce3da3551d7abd11 227 Gene3D G3DSA:3.10.129.10 75 213 1.5E-17 T 06-07-2017 IPR029069 HotDog domain BWK49_RS06485 6fa9a7aec7abdec416f2644de1274501 151 SUPERFAMILY SSF55961 4 141 7.91E-25 T 06-07-2017 BWK49_RS06485 6fa9a7aec7abdec416f2644de1274501 151 Gene3D G3DSA:3.30.530.20 5 141 4.2E-9 T 06-07-2017 IPR023393 START-like domain BWK49_RS06485 6fa9a7aec7abdec416f2644de1274501 151 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 3 141 7.2E-14 T 06-07-2017 IPR019587 Polyketide cyclase/dehydrase BWK49_RS18415 26e63597a066b9c481ed20c3376e692f 503 SUPERFAMILY SSF51905 16 236 1.84E-56 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS18415 26e63597a066b9c481ed20c3376e692f 503 SUPERFAMILY SSF51905 306 415 1.84E-56 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS18415 26e63597a066b9c481ed20c3376e692f 503 Gene3D G3DSA:3.50.50.60 299 499 3.2E-12 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS18415 26e63597a066b9c481ed20c3376e692f 503 Gene3D G3DSA:3.50.50.60 12 218 5.7E-61 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS18415 26e63597a066b9c481ed20c3376e692f 503 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 19 215 3.4E-20 T 06-07-2017 BWK49_RS18415 26e63597a066b9c481ed20c3376e692f 503 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 17 39 6.6E-6 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 BWK49_RS18415 26e63597a066b9c481ed20c3376e692f 503 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 179 203 6.6E-6 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 BWK49_RS05345 ef9535c5aa3611d8801c5dd7bd63fc50 282 Pfam PF02515 CoA-transferase family III 6 266 8.7E-43 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 BWK49_RS05345 ef9535c5aa3611d8801c5dd7bd63fc50 282 SUPERFAMILY SSF89796 3 282 1.83E-60 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS05345 ef9535c5aa3611d8801c5dd7bd63fc50 282 Gene3D G3DSA:3.40.50.10540 4 268 1.6E-56 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS25125 e57ea4569bebf5a7c4f880f41a9bf1c8 123 Pfam PF14012 Protein of unknown function (DUF4229) 31 99 9.0E-21 T 06-07-2017 IPR025323 Protein of unknown function DUF4229 BWK49_RS27420 56e83ade1b83c043d1bafe4e49c03a02 211 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 57 9.2E-13 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS27420 56e83ade1b83c043d1bafe4e49c03a02 211 SUPERFAMILY SSF46689 6 76 2.05E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS27420 56e83ade1b83c043d1bafe4e49c03a02 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 4.2E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS27420 56e83ade1b83c043d1bafe4e49c03a02 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 4.2E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS27420 56e83ade1b83c043d1bafe4e49c03a02 211 SUPERFAMILY SSF48498 82 201 1.75E-19 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS27420 56e83ade1b83c043d1bafe4e49c03a02 211 Gene3D G3DSA:1.10.357.10 62 199 2.3E-27 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS27420 56e83ade1b83c043d1bafe4e49c03a02 211 Gene3D G3DSA:1.10.10.60 8 61 1.9E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS03830 62a8934037fc6fdb169c30e6f81cfceb 176 Gene3D G3DSA:1.10.260.40 92 151 1.2E-4 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 BWK49_RS27090 680e45e0a499a1f0875f3f508c38bbd3 185 SUPERFAMILY SSF47413 113 166 3.56E-7 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 BWK49_RS27090 680e45e0a499a1f0875f3f508c38bbd3 185 Gene3D G3DSA:1.10.260.40 119 169 2.2E-6 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 BWK49_RS23345 9390ed081d040933f9302d58fdd90fc0 400 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 24 347 2.2E-57 T 06-07-2017 IPR017439 Amidohydrolase GO:0016787 BWK49_RS23345 9390ed081d040933f9302d58fdd90fc0 400 Gene3D G3DSA:3.40.630.10 282 392 3.7E-61 T 06-07-2017 BWK49_RS23345 9390ed081d040933f9302d58fdd90fc0 400 Gene3D G3DSA:3.40.630.10 9 173 3.7E-61 T 06-07-2017 BWK49_RS23345 9390ed081d040933f9302d58fdd90fc0 400 SUPERFAMILY SSF53187 15 185 1.89E-54 T 06-07-2017 BWK49_RS23345 9390ed081d040933f9302d58fdd90fc0 400 SUPERFAMILY SSF53187 285 378 1.89E-54 T 06-07-2017 BWK49_RS23345 9390ed081d040933f9302d58fdd90fc0 400 Gene3D G3DSA:3.30.70.360 174 276 1.7E-23 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain BWK49_RS23345 9390ed081d040933f9302d58fdd90fc0 400 SUPERFAMILY SSF55031 174 276 2.09E-21 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain BWK49_RS23345 9390ed081d040933f9302d58fdd90fc0 400 Pfam PF01546 Peptidase family M20/M25/M40 94 346 1.2E-8 T 06-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 BWK49_RS23345 9390ed081d040933f9302d58fdd90fc0 400 Pfam PF07687 Peptidase dimerisation domain 173 262 1.1E-7 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain BWK49_RS23345 9390ed081d040933f9302d58fdd90fc0 400 PIRSF PIRSF037226 5 398 3.4E-148 T 06-07-2017 IPR017144 Peptidase M20A, amidohydrolase, predicted BWK49_RS03710 f6fa9b1ae00bd81038b49faab45413b3 222 SUPERFAMILY SSF50494 47 214 1.09E-18 T 06-07-2017 IPR009003 Peptidase S1, PA clan BWK49_RS03710 f6fa9b1ae00bd81038b49faab45413b3 222 Gene3D G3DSA:2.40.10.10 41 116 2.5E-13 T 06-07-2017 BWK49_RS03710 f6fa9b1ae00bd81038b49faab45413b3 222 Gene3D G3DSA:2.40.10.10 125 215 1.1E-8 T 06-07-2017 BWK49_RS15845 0226691c1b2826f44ff448134c5b6523 327 Gene3D G3DSA:3.40.50.1820 6 306 7.7E-84 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS15845 0226691c1b2826f44ff448134c5b6523 327 Pfam PF07859 alpha/beta hydrolase fold 78 284 3.9E-66 T 06-07-2017 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 BWK49_RS15845 0226691c1b2826f44ff448134c5b6523 327 SUPERFAMILY SSF53474 35 308 1.21E-67 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS18925 8891bd65ca54166bed3277663e24df0c 609 Pfam PF00999 Sodium/hydrogen exchanger family 34 470 1.6E-59 T 06-07-2017 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 BWK49_RS11110 39f8a2c52eed48620e313562be56e6e7 275 Pfam PF00378 Enoyl-CoA hydratase/isomerase 17 273 1.4E-41 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 BWK49_RS11110 39f8a2c52eed48620e313562be56e6e7 275 Gene3D G3DSA:3.90.226.10 4 273 1.4E-67 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS11110 39f8a2c52eed48620e313562be56e6e7 275 SUPERFAMILY SSF52096 3 273 8.11E-66 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS27190 9f678933bb6e3f7f086f6305858d4422 377 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 3 73 1.6E-7 T 06-07-2017 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 BWK49_RS27190 9f678933bb6e3f7f086f6305858d4422 377 Gene3D G3DSA:3.40.50.720 2 164 1.2E-17 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS27190 9f678933bb6e3f7f086f6305858d4422 377 SUPERFAMILY SSF51735 2 103 3.32E-13 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS04895 b0813b2cf004f26e136acac4d74386ab 230 Pfam PF02371 Transposase IS116/IS110/IS902 family 122 203 1.2E-9 T 06-07-2017 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 BWK49_RS02335 16300c345e16f1253841dd9a6da7688a 362 Gene3D G3DSA:3.40.50.720 2 177 8.2E-18 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS02335 16300c345e16f1253841dd9a6da7688a 362 SUPERFAMILY SSF51735 7 126 9.46E-10 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS04655 6d814d39f9f94106f7cde24be55bed56 336 Pfam PF07859 alpha/beta hydrolase fold 103 304 2.5E-43 T 06-07-2017 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 BWK49_RS04655 6d814d39f9f94106f7cde24be55bed56 336 SUPERFAMILY SSF53474 68 326 5.68E-46 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS04655 6d814d39f9f94106f7cde24be55bed56 336 Gene3D G3DSA:3.40.50.1820 57 327 2.8E-52 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS14135 7d29645b23b8c8413125237c453db748 385 Gene3D G3DSA:3.60.21.10 257 312 7.3E-15 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like BWK49_RS14135 7d29645b23b8c8413125237c453db748 385 Gene3D G3DSA:3.60.21.10 11 220 7.3E-15 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like BWK49_RS14135 7d29645b23b8c8413125237c453db748 385 SUPERFAMILY SSF56300 13 211 2.46E-17 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like BWK49_RS14135 7d29645b23b8c8413125237c453db748 385 SUPERFAMILY SSF56300 242 316 2.46E-17 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like BWK49_RS14750 4361daa3f4d28744b4b4b02cf6f77229 153 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 4 149 1.9E-19 T 06-07-2017 IPR019587 Polyketide cyclase/dehydrase BWK49_RS14750 4361daa3f4d28744b4b4b02cf6f77229 153 SUPERFAMILY SSF55961 3 150 1.94E-23 T 06-07-2017 BWK49_RS14750 4361daa3f4d28744b4b4b02cf6f77229 153 Gene3D G3DSA:3.30.530.20 5 149 8.3E-15 T 06-07-2017 IPR023393 START-like domain BWK49_RS14745 9df8550579f55ed86b483e3516d5892d 145 Gene3D G3DSA:1.10.530.10 19 119 4.7E-38 T 06-07-2017 BWK49_RS14745 9df8550579f55ed86b483e3516d5892d 145 SUPERFAMILY SSF53955 44 119 2.17E-29 T 06-07-2017 IPR023346 Lysozyme-like domain BWK49_RS14745 9df8550579f55ed86b483e3516d5892d 145 Pfam PF06737 Transglycosylase-like domain 42 113 3.6E-31 T 06-07-2017 IPR010618 Transglycosylase-like BWK49_RS18755 69632b545cd1dd39ebbbbdf7799992de 498 Pfam PF02720 Domain of unknown function (DUF222) 40 339 1.7E-83 T 06-07-2017 IPR003870 Domain of unknown function DUF222 BWK49_RS18755 69632b545cd1dd39ebbbbdf7799992de 498 SMART SM00507 330 382 1.3E-7 T 06-07-2017 IPR003615 HNH nuclease BWK49_RS18755 69632b545cd1dd39ebbbbdf7799992de 498 Pfam PF01844 HNH endonuclease 342 384 5.8E-5 T 06-07-2017 IPR002711 HNH endonuclease GO:0003676|GO:0004519 BWK49_RS10925 5714db623540d51458f302441005358e 137 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 56 114 1.1E-18 T 06-07-2017 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal BWK49_RS10925 5714db623540d51458f302441005358e 137 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 17 53 1.7E-13 T 06-07-2017 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal BWK49_RS10925 5714db623540d51458f302441005358e 137 SUPERFAMILY SSF50249 3 120 9.25E-36 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS03005 44757278e54954ff892d4aa5d8b4bae3 203 Gene3D G3DSA:3.40.50.2020 12 202 6.7E-79 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like BWK49_RS03005 44757278e54954ff892d4aa5d8b4bae3 203 SUPERFAMILY SSF53271 22 198 4.46E-52 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like BWK49_RS03005 44757278e54954ff892d4aa5d8b4bae3 203 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 26 196 2.9E-67 T 06-07-2017 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620 BWK49_RS03005 44757278e54954ff892d4aa5d8b4bae3 203 Pfam PF00156 Phosphoribosyl transferase domain 46 183 2.1E-20 T 06-07-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 BWK49_RS13375 8ff0f5abebfed9794e1f6ef46b1c8813 96 SUPERFAMILY SSF103007 1 91 1.57E-28 T 06-07-2017 IPR007546 Protein of unknown function DUF503 BWK49_RS13375 8ff0f5abebfed9794e1f6ef46b1c8813 96 Pfam PF04456 Protein of unknown function (DUF503) 3 89 7.7E-30 T 06-07-2017 IPR007546 Protein of unknown function DUF503 BWK49_RS13375 8ff0f5abebfed9794e1f6ef46b1c8813 96 Gene3D G3DSA:3.30.70.1120 1 93 8.2E-34 T 06-07-2017 IPR007546 Protein of unknown function DUF503 BWK49_RS02995 a6ef2c4af345503cbe5ce723e20a0a68 355 TIGRFAM TIGR03883 DUF2342_F420: uncharacterized protein, coenzyme F420 biosynthesis associated 13 354 1.0E-124 T 06-07-2017 IPR022454 Conserved hypothetical protein CHP03883, F420 biosynthesis associated BWK49_RS02995 a6ef2c4af345503cbe5ce723e20a0a68 355 SUPERFAMILY SSF55486 13 354 5.79E-98 T 06-07-2017 BWK49_RS02995 a6ef2c4af345503cbe5ce723e20a0a68 355 TIGRFAM TIGR03624 TIGR03624: putative hydrolase 13 354 1.2E-114 T 06-07-2017 IPR018766 Zinicin-like metallopeptidase type 2 BWK49_RS02995 a6ef2c4af345503cbe5ce723e20a0a68 355 Pfam PF10103 Zinicin-like metallopeptidase 13 351 4.6E-102 T 06-07-2017 IPR018766 Zinicin-like metallopeptidase type 2 BWK49_RS05480 711746618c72f365bca041e4ee9d4164 395 SUPERFAMILY SSF53901 269 382 2.7E-22 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS05480 711746618c72f365bca041e4ee9d4164 395 PIRSF PIRSF000429 15 392 2.7E-36 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 BWK49_RS05480 711746618c72f365bca041e4ee9d4164 395 SUPERFAMILY SSF53901 19 232 5.26E-30 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS05480 711746618c72f365bca041e4ee9d4164 395 Gene3D G3DSA:3.40.47.10 198 228 3.8E-12 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS05480 711746618c72f365bca041e4ee9d4164 395 Gene3D G3DSA:3.40.47.10 33 123 3.8E-12 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS05480 711746618c72f365bca041e4ee9d4164 395 Pfam PF00108 Thiolase, N-terminal domain 20 131 6.1E-8 T 06-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 BWK49_RS05480 711746618c72f365bca041e4ee9d4164 395 Gene3D G3DSA:3.40.47.10 151 185 8.3E-12 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS05480 711746618c72f365bca041e4ee9d4164 395 Gene3D G3DSA:3.40.47.10 256 388 8.3E-12 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS07565 5166bdc55cfc7d35be9090a1f0763912 29 Pfam PF09604 F subunit of K+-transporting ATPase (Potass_KdpF) 7 29 2.3E-4 T 06-07-2017 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 BWK49_RS10085 744159c6930f23a08472c838fb6df36c 277 Pfam PF02645 Uncharacterised protein, DegV family COG1307 3 272 8.4E-73 T 06-07-2017 IPR003797 DegV BWK49_RS10085 744159c6930f23a08472c838fb6df36c 277 Gene3D G3DSA:3.30.1180.10 150 272 9.7E-35 T 06-07-2017 BWK49_RS10085 744159c6930f23a08472c838fb6df36c 277 SUPERFAMILY SSF82549 3 272 2.22E-69 T 06-07-2017 BWK49_RS10085 744159c6930f23a08472c838fb6df36c 277 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 4 272 9.1E-74 T 06-07-2017 IPR003797 DegV BWK49_RS10085 744159c6930f23a08472c838fb6df36c 277 Gene3D G3DSA:3.40.50.10170 3 144 1.9E-38 T 06-07-2017 BWK49_RS26515 445421fb998d9ef5e3a833d67d782aff 220 Gene3D G3DSA:1.10.357.10 57 202 3.6E-14 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS26515 445421fb998d9ef5e3a833d67d782aff 220 SUPERFAMILY SSF46689 22 94 5.13E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS26515 445421fb998d9ef5e3a833d67d782aff 220 Gene3D G3DSA:1.10.10.60 20 56 1.0E-6 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS16855 19a1cb24e00a55e5956bb5b9d56e5d54 77 Pfam PF13490 Putative zinc-finger 6 39 2.6E-10 T 06-07-2017 IPR027383 Putative zinc-finger BWK49_RS16745 e0de9995aaa2283e2b3a6fe366838bf8 596 Gene3D G3DSA:1.50.10.10 240 590 3.6E-49 T 06-07-2017 IPR012341 Six-hairpin glycosidase GO:0003824 BWK49_RS16745 e0de9995aaa2283e2b3a6fe366838bf8 596 Pfam PF00723 Glycosyl hydrolases family 15 252 528 3.5E-25 T 06-07-2017 IPR011613 Glycoside hydrolase family 15/Phosphorylase b kinase regulatory chain family Reactome: R-HSA-70221 BWK49_RS16745 e0de9995aaa2283e2b3a6fe366838bf8 596 SUPERFAMILY SSF48208 239 584 5.44E-64 T 06-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 BWK49_RS20960 fa665d2a6963b86218d49a40ca6de45c 376 Pfam PF07995 Glucose / Sorbosone dehydrogenase 82 228 3.7E-15 T 06-07-2017 IPR012938 Glucose/Sorbosone dehydrogenase GO:0005975|GO:0016901|GO:0048038 BWK49_RS20960 fa665d2a6963b86218d49a40ca6de45c 376 SUPERFAMILY SSF50952 70 339 3.01E-14 T 06-07-2017 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 BWK49_RS20960 fa665d2a6963b86218d49a40ca6de45c 376 Gene3D G3DSA:2.120.10.30 71 370 1.1E-34 T 06-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like BWK49_RS16270 424a9a04f1975c97120f60dd31bcad1f 100 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 6 93 5.5E-10 T 06-07-2017 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 BWK49_RS16270 424a9a04f1975c97120f60dd31bcad1f 100 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 1 100 12.751 T 06-07-2017 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 BWK49_RS13245 4dbc71f4b04dc63f7cd361704611ab51 95 TIGRFAM TIGR04529 MTB_hemophore: hemophore-related protein, Rv0203/Rv1174c family 24 95 1.2E-19 T 06-07-2017 IPR032407 Haemophore, haem-binding GO:0020037 BWK49_RS13245 4dbc71f4b04dc63f7cd361704611ab51 95 PIRSF PIRSF010611 1 95 4.6E-45 T 06-07-2017 IPR016572 Uncharacterised conserved protein UCP010611 BWK49_RS24050 d8a2a127fdc1caf51a5da381fe4e49d0 331 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 304 2.4E-77 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS24050 d8a2a127fdc1caf51a5da381fe4e49d0 331 Gene3D G3DSA:3.90.25.10 180 320 3.1E-42 T 06-07-2017 BWK49_RS24050 d8a2a127fdc1caf51a5da381fe4e49d0 331 SUPERFAMILY SSF51735 1 321 1.53E-88 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS24050 d8a2a127fdc1caf51a5da381fe4e49d0 331 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 2 318 4.1E-148 T 06-07-2017 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688 BWK49_RS24050 d8a2a127fdc1caf51a5da381fe4e49d0 331 Gene3D G3DSA:3.40.50.720 1 179 1.0E-61 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS16310 e9c2cacb40de47e14646ae5817824915 148 Gene3D G3DSA:3.40.50.2300 14 136 1.9E-37 T 06-07-2017 BWK49_RS16310 e9c2cacb40de47e14646ae5817824915 148 SUPERFAMILY SSF52172 6 135 3.13E-40 T 06-07-2017 IPR011006 CheY-like superfamily BWK49_RS16310 e9c2cacb40de47e14646ae5817824915 148 Pfam PF00072 Response regulator receiver domain 17 124 4.6E-27 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 BWK49_RS16310 e9c2cacb40de47e14646ae5817824915 148 SMART SM00448 14 124 5.0E-42 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 BWK49_RS06840 7967791246cd92085c9d5acf176dba5f 359 SUPERFAMILY SSF110857 5 124 8.37E-24 T 06-07-2017 IPR013024 Butirosin biosynthesis, BtrG-like BWK49_RS06840 7967791246cd92085c9d5acf176dba5f 359 Pfam PF13772 AIG2-like family 57 136 5.0E-13 T 06-07-2017 BWK49_RS06840 7967791246cd92085c9d5acf176dba5f 359 Pfam PF05908 Poly-gamma-glutamate hydrolase 172 321 6.9E-39 T 06-07-2017 IPR008585 Poly-gamma-glutamate hydrolase BWK49_RS06840 7967791246cd92085c9d5acf176dba5f 359 Gene3D G3DSA:3.10.490.10 5 149 4.0E-45 T 06-07-2017 IPR013024 Butirosin biosynthesis, BtrG-like BWK49_RS18155 344cf9245e681b8cff3a67c176b73f83 394 TIGRFAM TIGR01981 sufD: FeS assembly protein SufD 100 378 2.5E-78 T 06-07-2017 IPR011542 SUF system FeS cluster assembly, SufD GO:0016226 BWK49_RS18155 344cf9245e681b8cff3a67c176b73f83 394 SUPERFAMILY SSF101960 29 387 2.22E-86 T 06-07-2017 BWK49_RS18155 344cf9245e681b8cff3a67c176b73f83 394 Pfam PF01458 Uncharacterized protein family (UPF0051) 135 361 5.0E-67 T 06-07-2017 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 BWK49_RS14935 2cd35ed2b030408dd9f4ba3ff639755e 369 PRINTS PR01217 Proline rich extensin signature 57 69 8.9E-9 T 06-07-2017 BWK49_RS14935 2cd35ed2b030408dd9f4ba3ff639755e 369 PRINTS PR01217 Proline rich extensin signature 102 118 8.9E-9 T 06-07-2017 BWK49_RS14935 2cd35ed2b030408dd9f4ba3ff639755e 369 PRINTS PR01217 Proline rich extensin signature 34 50 8.9E-9 T 06-07-2017 BWK49_RS14935 2cd35ed2b030408dd9f4ba3ff639755e 369 PRINTS PR01217 Proline rich extensin signature 76 97 8.9E-9 T 06-07-2017 BWK49_RS14935 2cd35ed2b030408dd9f4ba3ff639755e 369 Pfam PF07174 Fibronectin-attachment protein (FAP) 95 306 4.0E-110 T 06-07-2017 IPR010801 Fibronectin-attachment GO:0005576|GO:0050840 BWK49_RS14935 2cd35ed2b030408dd9f4ba3ff639755e 369 Pfam PF07174 Fibronectin-attachment protein (FAP) 1 104 1.3E-20 T 06-07-2017 IPR010801 Fibronectin-attachment GO:0005576|GO:0050840 BWK49_RS04410 8e2b4b69891f5c32ded57243f83e6ee7 97 Gene3D G3DSA:1.10.287.1060 4 94 4.4E-6 T 06-07-2017 BWK49_RS04410 8e2b4b69891f5c32ded57243f83e6ee7 97 SUPERFAMILY SSF140453 3 94 1.7E-9 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like BWK49_RS18020 39d5622b2a41d789209d57c4d741dd38 217 Gene3D G3DSA:3.40.109.10 6 217 1.2E-34 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 BWK49_RS18020 39d5622b2a41d789209d57c4d741dd38 217 SUPERFAMILY SSF55469 106 217 7.2E-36 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 BWK49_RS18020 39d5622b2a41d789209d57c4d741dd38 217 SUPERFAMILY SSF55469 7 69 7.2E-36 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 BWK49_RS18020 39d5622b2a41d789209d57c4d741dd38 217 Pfam PF00881 Nitroreductase family 14 183 7.2E-23 T 06-07-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 BWK49_RS00900 dcab07057e9c2f5f6edb5247ea23ad92 283 Gene3D G3DSA:3.40.50.720 1 209 7.0E-28 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS00900 dcab07057e9c2f5f6edb5247ea23ad92 283 SUPERFAMILY SSF51735 2 257 1.39E-42 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS00900 dcab07057e9c2f5f6edb5247ea23ad92 283 Pfam PF13460 NAD(P)H-binding 7 175 1.7E-14 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS15945 a4db19d226e4e196d0332362806aa969 497 SUPERFAMILY SSF103473 8 473 3.79E-71 T 06-07-2017 IPR020846 Major facilitator superfamily domain BWK49_RS15945 a4db19d226e4e196d0332362806aa969 497 Gene3D G3DSA:1.20.1250.20 278 471 1.4E-18 T 06-07-2017 BWK49_RS15945 a4db19d226e4e196d0332362806aa969 497 Gene3D G3DSA:1.20.1250.20 34 227 1.7E-27 T 06-07-2017 BWK49_RS15945 a4db19d226e4e196d0332362806aa969 497 Pfam PF00083 Sugar (and other) transporter 67 474 2.5E-46 T 06-07-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 BWK49_RS25145 0443623a25d56e5763db4cd2923d4904 548 Pfam PF05140 ResB-like family 18 517 2.0E-132 T 06-07-2017 IPR007816 ResB-like domain BWK49_RS04725 01b0909c58c8410ffff97efaea38e7a7 422 Gene3D G3DSA:3.40.47.10 181 218 4.1E-15 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS04725 01b0909c58c8410ffff97efaea38e7a7 422 Gene3D G3DSA:3.40.47.10 280 407 4.1E-15 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS04725 01b0909c58c8410ffff97efaea38e7a7 422 SUPERFAMILY SSF53901 269 410 2.04E-23 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS04725 01b0909c58c8410ffff97efaea38e7a7 422 SUPERFAMILY SSF53901 48 265 3.96E-18 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS04725 01b0909c58c8410ffff97efaea38e7a7 422 Gene3D G3DSA:3.40.47.10 231 261 4.8E-11 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS04725 01b0909c58c8410ffff97efaea38e7a7 422 Gene3D G3DSA:3.40.47.10 61 147 4.8E-11 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS18765 ca9f336c6c34ce9d8c8abc056e769238 222 SUPERFAMILY SSF56281 6 220 1.83E-47 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS18765 ca9f336c6c34ce9d8c8abc056e769238 222 SMART SM00849 12 203 1.2E-37 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS18765 ca9f336c6c34ce9d8c8abc056e769238 222 Gene3D G3DSA:3.60.15.10 9 220 1.0E-53 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS18765 ca9f336c6c34ce9d8c8abc056e769238 222 Pfam PF00753 Metallo-beta-lactamase superfamily 11 203 1.2E-28 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS08750 8847a68008e77009ee53b3ad0607681e 176 Pfam PF12079 Protein of unknown function (DUF3558) 13 173 1.7E-29 T 06-07-2017 IPR024520 Protein of unknown function DUF3558 BWK49_RS04000 a1def66226bbe776c5623b5b868c119a 289 SUPERFAMILY SSF53474 2 285 1.53E-67 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS04000 a1def66226bbe776c5623b5b868c119a 289 Pfam PF00561 alpha/beta hydrolase fold 30 268 3.3E-26 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS04000 a1def66226bbe776c5623b5b868c119a 289 PRINTS PR00412 Epoxide hydrolase signature 228 244 3.6E-8 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS04000 a1def66226bbe776c5623b5b868c119a 289 PRINTS PR00412 Epoxide hydrolase signature 260 282 3.6E-8 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS04000 a1def66226bbe776c5623b5b868c119a 289 PRINTS PR00412 Epoxide hydrolase signature 99 112 3.6E-8 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS04000 a1def66226bbe776c5623b5b868c119a 289 PRINTS PR00412 Epoxide hydrolase signature 113 126 3.6E-8 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS04000 a1def66226bbe776c5623b5b868c119a 289 PRINTS PR00412 Epoxide hydrolase signature 33 51 3.6E-8 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS04000 a1def66226bbe776c5623b5b868c119a 289 Gene3D G3DSA:3.40.50.1820 3 285 8.9E-64 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS21480 add4f85a86c385768b86a172c4705402 146 Pfam PF07681 DoxX 17 93 1.9E-9 T 06-07-2017 IPR032808 DoxX family BWK49_RS07520 f11fadd0d862090b1be03df4f026589c 233 Pfam PF04977 Septum formation initiator 86 162 1.5E-18 T 06-07-2017 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 BWK49_RS06420 6c5ff7fb9ea495824d3754f7a68f3166 431 Gene3D G3DSA:1.10.630.10 10 423 8.7E-102 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS06420 6c5ff7fb9ea495824d3754f7a68f3166 431 Pfam PF00067 Cytochrome P450 219 384 8.1E-24 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS06420 6c5ff7fb9ea495824d3754f7a68f3166 431 SUPERFAMILY SSF48264 10 422 7.07E-83 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS06420 6c5ff7fb9ea495824d3754f7a68f3166 431 PRINTS PR00359 B-class P450 signature 305 332 4.8E-39 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS06420 6c5ff7fb9ea495824d3754f7a68f3166 431 PRINTS PR00359 B-class P450 signature 147 163 4.8E-39 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS06420 6c5ff7fb9ea495824d3754f7a68f3166 431 PRINTS PR00359 B-class P450 signature 333 348 4.8E-39 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS06420 6c5ff7fb9ea495824d3754f7a68f3166 431 PRINTS PR00359 B-class P450 signature 101 112 4.8E-39 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS06420 6c5ff7fb9ea495824d3754f7a68f3166 431 PRINTS PR00359 B-class P450 signature 355 364 4.8E-39 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS06420 6c5ff7fb9ea495824d3754f7a68f3166 431 PRINTS PR00359 B-class P450 signature 164 179 4.8E-39 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS06420 6c5ff7fb9ea495824d3754f7a68f3166 431 PRINTS PR00359 B-class P450 signature 288 299 4.8E-39 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS06420 6c5ff7fb9ea495824d3754f7a68f3166 431 PRINTS PR00359 B-class P450 signature 206 228 4.8E-39 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS06420 6c5ff7fb9ea495824d3754f7a68f3166 431 PRINTS PR00359 B-class P450 signature 364 375 4.8E-39 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 BWK49_RS16625 7309ebc62ae403b6e0b45c2fcdebe989 249 Gene3D G3DSA:3.40.50.150 27 218 2.0E-47 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS16625 7309ebc62ae403b6e0b45c2fcdebe989 249 SUPERFAMILY SSF53335 34 219 5.21E-33 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS16625 7309ebc62ae403b6e0b45c2fcdebe989 249 Pfam PF01596 O-methyltransferase 59 204 6.4E-15 T 06-07-2017 IPR002935 O-methyltransferase, family 3 GO:0008171 BWK49_RS12635 6eaf0dbf8a81792c8e950215e851a14a 214 SUPERFAMILY SSF54637 13 206 2.67E-40 T 06-07-2017 IPR029069 HotDog domain BWK49_RS12635 6eaf0dbf8a81792c8e950215e851a14a 214 Pfam PF03061 Thioesterase superfamily 127 198 8.5E-5 T 06-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 BWK49_RS12635 6eaf0dbf8a81792c8e950215e851a14a 214 Gene3D G3DSA:3.10.129.10 88 209 1.5E-31 T 06-07-2017 IPR029069 HotDog domain BWK49_RS06810 c5ac2e83fcaa982d094236a060591bc2 458 Pfam PF00823 PPE family 5 160 2.0E-60 T 06-07-2017 IPR000030 PPE family BWK49_RS06810 c5ac2e83fcaa982d094236a060591bc2 458 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 306 376 7.1E-10 T 06-07-2017 IPR022171 PPE family, C-terminal BWK49_RS06810 c5ac2e83fcaa982d094236a060591bc2 458 SUPERFAMILY SSF140459 2 173 5.75E-64 T 06-07-2017 BWK49_RS00200 ed35298003b9fa6946d309d9a05682be 262 SUPERFAMILY SSF47413 6 62 3.49E-11 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 BWK49_RS00200 ed35298003b9fa6946d309d9a05682be 262 Pfam PF01381 Helix-turn-helix 10 61 6.8E-11 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 BWK49_RS00200 ed35298003b9fa6946d309d9a05682be 262 Gene3D G3DSA:1.10.260.40 6 61 8.7E-12 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 BWK49_RS00200 ed35298003b9fa6946d309d9a05682be 262 SMART SM00530 9 64 5.0E-11 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 BWK49_RS02190 3bd22aef301286012b070761f0954fc0 329 Pfam PF02153 Prephenate dehydrogenase 36 267 8.3E-42 T 06-07-2017 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 BWK49_RS02190 3bd22aef301286012b070761f0954fc0 329 SUPERFAMILY SSF48179 185 283 5.1E-21 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 BWK49_RS02190 3bd22aef301286012b070761f0954fc0 329 SUPERFAMILY SSF51735 16 179 4.22E-31 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS02190 3bd22aef301286012b070761f0954fc0 329 Gene3D G3DSA:3.40.50.720 10 189 6.9E-30 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS06330 445692ecf58ef5eeb3db79e175c25756 401 Pfam PF02515 CoA-transferase family III 4 373 6.6E-82 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 BWK49_RS06330 445692ecf58ef5eeb3db79e175c25756 401 Gene3D G3DSA:3.30.1540.10 234 315 1.5E-20 T 06-07-2017 BWK49_RS06330 445692ecf58ef5eeb3db79e175c25756 401 SUPERFAMILY SSF89796 2 400 2.22E-95 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS06330 445692ecf58ef5eeb3db79e175c25756 401 Gene3D G3DSA:3.40.50.10540 2 222 8.5E-75 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS06330 445692ecf58ef5eeb3db79e175c25756 401 Gene3D G3DSA:3.40.50.10540 316 400 8.5E-75 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS13875 5b4c6eb9165632dfc978b4378df10d43 129 Pfam PF08818 Domain of unknown function (DU1801) 30 124 1.5E-19 T 06-07-2017 IPR014922 Domain of unknown function DUF1801 BWK49_RS13875 5b4c6eb9165632dfc978b4378df10d43 129 SUPERFAMILY SSF159888 18 128 3.53E-19 T 06-07-2017 BWK49_RS10960 0683cf8d3590f32b083aa14d1e35967c 158 Gene3D G3DSA:3.10.129.10 16 155 5.2E-37 T 06-07-2017 IPR029069 HotDog domain BWK49_RS10960 0683cf8d3590f32b083aa14d1e35967c 158 SUPERFAMILY SSF54637 11 152 7.26E-40 T 06-07-2017 IPR029069 HotDog domain BWK49_RS10960 0683cf8d3590f32b083aa14d1e35967c 158 Pfam PF01575 MaoC like domain 17 137 7.3E-28 T 06-07-2017 IPR002539 MaoC-like domain BWK49_RS00365 34b9bb56f16851b3ebd057c7e8bd6195 548 Pfam PF09594 Protein of unknown function (DUF2029) 181 414 3.4E-17 T 06-07-2017 IPR018584 Glycosyltransferase family 87 GO:0016758 BWK49_RS00365 34b9bb56f16851b3ebd057c7e8bd6195 548 PIRSF PIRSF010361 27 516 2.3E-185 T 06-07-2017 IPR016570 Uncharacterised conserved protein UCP010361, membrane BWK49_RS11365 99e2d13082846ffa08d37c3e5e55e9dd 256 Pfam PF00975 Thioesterase domain 36 253 1.6E-42 T 06-07-2017 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 BWK49_RS11365 99e2d13082846ffa08d37c3e5e55e9dd 256 Gene3D G3DSA:3.40.50.1820 32 137 1.0E-28 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS11365 99e2d13082846ffa08d37c3e5e55e9dd 256 Gene3D G3DSA:3.40.50.1820 198 254 1.0E-28 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS11365 99e2d13082846ffa08d37c3e5e55e9dd 256 SUPERFAMILY SSF53474 9 254 3.98E-39 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS12190 f2361b9dce901ff835623423be70b829 144 SUPERFAMILY SSF141066 40 143 8.89E-24 T 06-07-2017 IPR018990 Proteinase inhibitor I42, chagasin BWK49_RS12190 f2361b9dce901ff835623423be70b829 144 Pfam PF09394 Chagasin family peptidase inhibitor I42 51 141 1.6E-20 T 06-07-2017 IPR018990 Proteinase inhibitor I42, chagasin BWK49_RS03035 47f21e78e1945d7dd0b9feea30404206 395 SUPERFAMILY SSF51679 5 352 1.65E-74 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS03035 47f21e78e1945d7dd0b9feea30404206 395 Gene3D G3DSA:3.20.20.30 6 351 7.5E-79 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS03035 47f21e78e1945d7dd0b9feea30404206 395 Pfam PF00296 Luciferase-like monooxygenase 6 316 5.2E-42 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS28110 18d9e5c4fc245be136aef947a31a0a16 386 Gene3D G3DSA:3.40.47.10 127 170 7.8E-7 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS28110 18d9e5c4fc245be136aef947a31a0a16 386 Gene3D G3DSA:3.40.47.10 240 373 7.8E-7 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS28110 18d9e5c4fc245be136aef947a31a0a16 386 Gene3D G3DSA:3.40.47.10 183 212 3.7E-4 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS28110 18d9e5c4fc245be136aef947a31a0a16 386 Gene3D G3DSA:3.40.47.10 80 102 3.7E-4 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS28110 18d9e5c4fc245be136aef947a31a0a16 386 SUPERFAMILY SSF53901 8 211 2.07E-18 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS28110 18d9e5c4fc245be136aef947a31a0a16 386 SUPERFAMILY SSF53901 249 370 3.38E-15 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS13085 a4dd95da2c87248616061a30188f2a86 565 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 397 421 - T 06-07-2017 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 BWK49_RS13085 a4dd95da2c87248616061a30188f2a86 565 Pfam PF01098 Cell cycle protein 85 439 1.4E-121 T 06-07-2017 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 BWK49_RS13085 a4dd95da2c87248616061a30188f2a86 565 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 86 438 2.2E-119 T 06-07-2017 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 BWK49_RS07705 706dd88b0ce992b5b902b849a816830d 283 PIRSF PIRSF009160 1 283 4.6E-96 T 06-07-2017 IPR010539 Protein of unknown function UCP009160 BWK49_RS07705 706dd88b0ce992b5b902b849a816830d 283 Pfam PF12811 Bax inhibitor 1 like 33 282 1.8E-86 T 06-07-2017 IPR010539 Protein of unknown function UCP009160 BWK49_RS16030 4639b38648f840bcfba299d315131ee5 327 Pfam PF05305 Protein of unknown function (DUF732) 15 121 1.4E-18 T 06-07-2017 IPR007969 Domain of unknown function DUF732 BWK49_RS17550 0124a4577a8e8712288b06859ed1394a 135 PIRSF PIRSF002030 1 129 1.3E-45 T 06-07-2017 IPR016339 Truncated hemoglobin, group 1 BWK49_RS17550 0124a4577a8e8712288b06859ed1394a 135 Gene3D G3DSA:1.10.490.10 10 130 1.0E-40 T 06-07-2017 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 BWK49_RS17550 0124a4577a8e8712288b06859ed1394a 135 ProSitePatterns PS01213 Protozoan/cyanobacterial globins signature. 61 81 - T 06-07-2017 IPR019795 Globin, bacterial-like, conserved site GO:0015671|GO:0019825 BWK49_RS17550 0124a4577a8e8712288b06859ed1394a 135 Pfam PF01152 Bacterial-like globin 14 125 5.9E-31 T 06-07-2017 IPR001486 Truncated hemoglobin GO:0019825 BWK49_RS17550 0124a4577a8e8712288b06859ed1394a 135 SUPERFAMILY SSF46458 3 126 9.96E-39 T 06-07-2017 IPR009050 Globin-like BWK49_RS02605 1ae42a466775e846cf4053938d0727a0 290 Pfam PF06271 RDD family 19 143 2.8E-14 T 06-07-2017 IPR010432 RDD BWK49_RS14820 478c7b7cb6af73be54da2f5cbeb34428 227 SUPERFAMILY SSF54909 112 184 2.49E-7 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel BWK49_RS14820 478c7b7cb6af73be54da2f5cbeb34428 227 Gene3D G3DSA:3.30.70.900 112 172 2.1E-4 T 06-07-2017 BWK49_RS14820 478c7b7cb6af73be54da2f5cbeb34428 227 Pfam PF07110 EthD domain 120 193 6.6E-6 T 06-07-2017 IPR009799 EthD domain BWK49_RS04435 6d5e3135c034a96c27db8f076640029b 514 Pfam PF11203 Putative type VII ESX secretion system translocon, EccE 174 270 8.0E-12 T 06-07-2017 IPR021368 Type VII secretion system protein EccE BWK49_RS04435 6d5e3135c034a96c27db8f076640029b 514 TIGRFAM TIGR03923 T7SS_EccE: type VII secretion protein EccE 22 344 2.0E-51 T 06-07-2017 IPR021368 Type VII secretion system protein EccE BWK49_RS22205 54663489a000a216f67826a0e909e2bd 99 Pfam PF13244 Domain of unknown function (DUF4040) 13 78 3.2E-13 T 06-07-2017 IPR025383 Domain of unknown function DUF4040 BWK49_RS16635 edb9f88fc3f82314356283a214eb44bf 207 Pfam PF00293 NUDIX domain 45 156 5.1E-13 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 BWK49_RS16635 edb9f88fc3f82314356283a214eb44bf 207 Gene3D G3DSA:3.90.79.10 7 178 7.8E-50 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 BWK49_RS16635 edb9f88fc3f82314356283a214eb44bf 207 SUPERFAMILY SSF55811 8 177 5.28E-44 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 BWK49_RS19740 d3ac05058c6fee4566aaa3b143c1231b 152 Gene3D G3DSA:1.25.40.10 111 150 9.6E-5 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 BWK49_RS19740 d3ac05058c6fee4566aaa3b143c1231b 152 SUPERFAMILY SSF48452 110 150 6.2E-5 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 BWK49_RS04715 cde54e91cd5781027a14291a94f9f1c3 465 Pfam PF07287 Protein of unknown function (DUF1446) 9 368 7.7E-102 T 06-07-2017 IPR010839 Protein of unknown function DUF1446 BWK49_RS23860 d497facbc1913545b926468893f3dfde 370 Gene3D G3DSA:3.40.50.1820 63 349 7.4E-51 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS23860 d497facbc1913545b926468893f3dfde 370 Pfam PF12146 Serine aminopeptidase, S33 84 335 6.2E-24 T 06-07-2017 IPR022742 Serine aminopeptidase, S33 BWK49_RS23860 d497facbc1913545b926468893f3dfde 370 SUPERFAMILY SSF53474 62 345 1.45E-45 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS23315 d58cfb7174581c37b80d806afb918645 286 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 128 142 - T 06-07-2017 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 BWK49_RS23315 d58cfb7174581c37b80d806afb918645 286 SUPERFAMILY SSF55120 73 282 4.96E-50 T 06-07-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 BWK49_RS23315 d58cfb7174581c37b80d806afb918645 286 Pfam PF00849 RNA pseudouridylate synthase 89 233 8.0E-22 T 06-07-2017 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 BWK49_RS29005 951ac29924c0a9e72a4167385c179d3b 504 Pfam PF08817 WXG100 protein secretion system (Wss), protein YukD 24 104 4.1E-12 T 06-07-2017 IPR024962 YukD-like BWK49_RS29005 951ac29924c0a9e72a4167385c179d3b 504 TIGRFAM TIGR03920 T7SS_EccD: type VII secretion integral membrane protein EccD 25 503 1.3E-89 T 06-07-2017 IPR006707 Type VII secretion system membrane protein EccD BWK49_RS29005 951ac29924c0a9e72a4167385c179d3b 504 PIRSF PIRSF017804 13 504 1.2E-47 T 06-07-2017 IPR006707 Type VII secretion system membrane protein EccD BWK49_RS03145 589a06db8863e0682e1c7a934b199887 205 ProSitePatterns PS00705 Prokaryotic-type carbonic anhydrases signature 2. 88 108 - T 06-07-2017 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 BWK49_RS03145 589a06db8863e0682e1c7a934b199887 205 ProSitePatterns PS00704 Prokaryotic-type carbonic anhydrases signature 1. 51 58 - T 06-07-2017 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 BWK49_RS03145 589a06db8863e0682e1c7a934b199887 205 Gene3D G3DSA:3.40.1050.10 4 198 1.9E-55 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 BWK49_RS03145 589a06db8863e0682e1c7a934b199887 205 SUPERFAMILY SSF53056 3 199 1.57E-54 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 BWK49_RS03145 589a06db8863e0682e1c7a934b199887 205 SMART SM00947 39 198 2.6E-49 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 BWK49_RS03145 589a06db8863e0682e1c7a934b199887 205 Pfam PF00484 Carbonic anhydrase 46 193 1.2E-38 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 BWK49_RS08280 ce7aaccc860f634fa114f6fcdbc547e3 204 Gene3D G3DSA:1.10.10.60 15 63 2.3E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS08280 ce7aaccc860f634fa114f6fcdbc547e3 204 SUPERFAMILY SSF48498 87 196 1.51E-12 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS08280 ce7aaccc860f634fa114f6fcdbc547e3 204 Gene3D G3DSA:1.10.357.10 65 195 1.5E-17 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS08280 ce7aaccc860f634fa114f6fcdbc547e3 204 Pfam PF16859 Bacterial transcriptional repressor C-terminal 87 193 1.7E-12 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS08280 ce7aaccc860f634fa114f6fcdbc547e3 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 71 2.8E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS08280 ce7aaccc860f634fa114f6fcdbc547e3 204 SUPERFAMILY SSF46689 14 76 5.64E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS22840 d986b46e7620615ab038fcc90530f6f9 158 Pfam PF01638 HxlR-like helix-turn-helix 28 116 3.0E-14 T 06-07-2017 IPR002577 Helix-turn-helix, HxlR type BWK49_RS22840 d986b46e7620615ab038fcc90530f6f9 158 SUPERFAMILY SSF46785 19 140 8.44E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS22840 d986b46e7620615ab038fcc90530f6f9 158 Gene3D G3DSA:1.10.10.10 19 118 1.5E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS22695 37d22eeb56d99d79b01a71b7f403d7be 235 Pfam PF05423 Mycobacterium membrane protein 141 213 8.0E-6 T 06-07-2017 IPR008693 Transport accessory protein MmpS BWK49_RS13805 e4c210f685241dc149188400286cff32 360 Pfam PF09375 Imelysin 106 350 4.0E-34 T 06-07-2017 BWK49_RS02470 d6b0ca51b6fc11fb280baec1708f470c 420 Pfam PF02353 Mycolic acid cyclopropane synthetase 131 398 4.6E-98 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS02470 d6b0ca51b6fc11fb280baec1708f470c 420 Gene3D G3DSA:3.40.50.150 130 402 2.5E-82 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS02470 d6b0ca51b6fc11fb280baec1708f470c 420 SUPERFAMILY SSF53335 141 403 1.69E-67 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS02470 d6b0ca51b6fc11fb280baec1708f470c 420 PIRSF PIRSF003085 1 420 2.6E-125 T 06-07-2017 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 BWK49_RS02470 d6b0ca51b6fc11fb280baec1708f470c 420 SMART SM00828 Methyltransferase in polyketide synthase (PKS) enzymes. 149 409 0.0054 T 06-07-2017 IPR020803 Polyketide synthase, methyltransferase domain BWK49_RS00225 85ae4faf979ae9fdede6c06724f4cafa 103 Pfam PF10904 Protein of unknown function (DUF2694) 1 97 2.0E-54 T 06-07-2017 IPR024426 Protein of unknown function DUF2694 BWK49_RS00225 85ae4faf979ae9fdede6c06724f4cafa 103 ProDom PD068262 MB0029 RV0028/MT0030.1 1 99 1.0E-50 T 06-07-2017 IPR024426 Protein of unknown function DUF2694 BWK49_RS15180 6e5491bada6bb794ac189c730fc65846 414 Pfam PF00823 PPE family 5 161 2.1E-59 T 06-07-2017 IPR000030 PPE family BWK49_RS15180 6e5491bada6bb794ac189c730fc65846 414 SUPERFAMILY SSF140459 2 173 7.85E-63 T 06-07-2017 BWK49_RS15180 6e5491bada6bb794ac189c730fc65846 414 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 315 385 2.9E-9 T 06-07-2017 IPR022171 PPE family, C-terminal BWK49_RS13025 a5db45a8616fb85ebe9cca87f5a45060 134 Pfam PF11239 Protein of unknown function (DUF3040) 1 88 3.4E-29 T 06-07-2017 IPR021401 Protein of unknown function DUF3040 BWK49_RS26835 bb2a67e96300997b6db7567b85b66238 185 PIRSF PIRSF024492 3 184 3.8E-50 T 06-07-2017 IPR014519 Uncharacterised conserved protein UCP024492 BWK49_RS26835 bb2a67e96300997b6db7567b85b66238 185 Pfam PF04343 Protein of unknown function, DUF488 19 138 8.5E-29 T 06-07-2017 IPR007438 Protein of unknown function DUF488 BWK49_RS14105 f204b86bedf90658cb237e1b38dcd15b 301 Pfam PF14417 MEDS: MEthanogen/methylotroph, DcmR Sensory domain 14 173 8.5E-20 T 06-07-2017 IPR025847 MEDS domain BWK49_RS00345 a137d40493641a41c653c4e53a296909 180 Pfam PF03551 Transcriptional regulator PadR-like family 6 81 2.2E-21 T 06-07-2017 IPR005149 Transcription regulator PadR, N-terminal BWK49_RS00345 a137d40493641a41c653c4e53a296909 180 SUPERFAMILY SSF46785 2 171 4.57E-35 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS00345 a137d40493641a41c653c4e53a296909 180 Gene3D G3DSA:1.10.10.10 1 86 4.2E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS08555 ffaea8327c9fa118b934e359d3f6e002 180 Pfam PF06210 Protein of unknown function (DUF1003) 39 139 8.6E-39 T 06-07-2017 IPR010406 Protein of unknown function DUF1003 BWK49_RS22620 811ffbf31130ad43d14ed808a2b3f801 83 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 75 15.776 T 06-07-2017 IPR003482 Transcription factor WhiB BWK49_RS22620 811ffbf31130ad43d14ed808a2b3f801 83 Pfam PF02467 Transcription factor WhiB 12 61 6.0E-17 T 06-07-2017 IPR003482 Transcription factor WhiB BWK49_RS29160 ce85b3a3500476b0a6bc02f77a3e38b0 1952 SUPERFAMILY SSF55464 198 454 2.24E-63 T 06-07-2017 BWK49_RS29160 ce85b3a3500476b0a6bc02f77a3e38b0 1952 SUPERFAMILY SSF55464 11 106 2.24E-63 T 06-07-2017 BWK49_RS29160 ce85b3a3500476b0a6bc02f77a3e38b0 1952 Pfam PF13604 AAA domain 604 810 8.0E-55 T 06-07-2017 BWK49_RS29160 ce85b3a3500476b0a6bc02f77a3e38b0 1952 SUPERFAMILY SSF52540 601 769 6.81E-22 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS29160 ce85b3a3500476b0a6bc02f77a3e38b0 1952 SUPERFAMILY SSF52540 828 997 7.97E-23 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS29160 ce85b3a3500476b0a6bc02f77a3e38b0 1952 SUPERFAMILY SSF52540 729 793 7.97E-23 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS29160 ce85b3a3500476b0a6bc02f77a3e38b0 1952 Pfam PF08751 TrwC relaxase 19 441 2.2E-87 T 06-07-2017 IPR014862 TrwC relaxase BWK49_RS29160 ce85b3a3500476b0a6bc02f77a3e38b0 1952 Gene3D G3DSA:3.40.50.300 598 775 2.2E-23 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS11550 39a700527e672844c3e3806e9b51361c 373 Gene3D G3DSA:3.20.20.30 5 114 2.5E-88 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS11550 39a700527e672844c3e3806e9b51361c 373 Gene3D G3DSA:3.20.20.30 158 367 2.5E-88 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS11550 39a700527e672844c3e3806e9b51361c 373 Pfam PF00296 Luciferase-like monooxygenase 12 339 5.9E-30 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS11550 39a700527e672844c3e3806e9b51361c 373 SUPERFAMILY SSF51679 178 367 1.01E-61 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS11550 39a700527e672844c3e3806e9b51361c 373 SUPERFAMILY SSF51679 6 141 1.01E-61 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS04175 18ae5d0bf0b922973233edfd63788f5d 204 Gene3D G3DSA:1.10.357.10 19 187 9.4E-19 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS04175 18ae5d0bf0b922973233edfd63788f5d 204 SUPERFAMILY SSF46689 16 87 2.21E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS04175 18ae5d0bf0b922973233edfd63788f5d 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 72 1.6E-4 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS01280 9b3bc161e38fbc97d27715dc5b0b7456 169 Pfam PF10759 Protein of unknown function (DUF2587) 25 158 2.3E-77 T 06-07-2017 IPR019695 Bacterial proteasome activator GO:0061136 BWK49_RS08175 60645665bf17e8215bf1b8ddaf23c838 210 Pfam PF13489 Methyltransferase domain 35 183 4.5E-17 T 06-07-2017 BWK49_RS08175 60645665bf17e8215bf1b8ddaf23c838 210 SUPERFAMILY SSF53335 12 209 6.91E-30 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS08175 60645665bf17e8215bf1b8ddaf23c838 210 Gene3D G3DSA:3.40.50.150 38 186 4.4E-21 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS10825 0e5538c25f07208f56e0a2116f864900 259 Gene3D G3DSA:3.40.50.720 7 229 6.4E-44 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS10825 0e5538c25f07208f56e0a2116f864900 259 SUPERFAMILY SSF51735 7 228 1.22E-43 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS10825 0e5538c25f07208f56e0a2116f864900 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 228 1.0E-31 T 06-07-2017 BWK49_RS10825 0e5538c25f07208f56e0a2116f864900 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 5.0E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS10825 0e5538c25f07208f56e0a2116f864900 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 5.0E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS10825 0e5538c25f07208f56e0a2116f864900 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 5.0E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS10825 0e5538c25f07208f56e0a2116f864900 259 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 11 183 8.5E-4 T 06-07-2017 BWK49_RS15820 65ed865cbb02beee91d88fd534ea4a6d 258 Pfam PF00378 Enoyl-CoA hydratase/isomerase 17 238 4.2E-53 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 BWK49_RS15820 65ed865cbb02beee91d88fd534ea4a6d 258 SUPERFAMILY SSF52096 6 254 1.77E-72 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS15820 65ed865cbb02beee91d88fd534ea4a6d 258 Gene3D G3DSA:3.90.226.10 9 245 1.3E-73 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS15820 65ed865cbb02beee91d88fd534ea4a6d 258 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 107 127 - T 06-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 BWK49_RS17775 3ccd9883b6c8fde6086db5d49492c917 428 SUPERFAMILY SSF56601 31 238 5.83E-60 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like BWK49_RS17775 3ccd9883b6c8fde6086db5d49492c917 428 SUPERFAMILY SSF56601 274 380 5.83E-60 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like BWK49_RS17775 3ccd9883b6c8fde6086db5d49492c917 428 Gene3D G3DSA:3.40.710.10 43 381 1.4E-66 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like BWK49_RS17775 3ccd9883b6c8fde6086db5d49492c917 428 Pfam PF00144 Beta-lactamase 46 381 1.1E-61 T 06-07-2017 IPR001466 Beta-lactamase-related BWK49_RS04455 ef180f0381d37c1ad88ed04548b9cfee 104 SUPERFAMILY SSF47413 1 42 4.79E-5 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 BWK49_RS04455 ef180f0381d37c1ad88ed04548b9cfee 104 Gene3D G3DSA:1.10.260.40 1 40 4.6E-4 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 BWK49_RS14770 2087d35a519a40d15ef19591bbb7647d 147 SUPERFAMILY SSF54427 4 126 2.34E-26 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS14770 2087d35a519a40d15ef19591bbb7647d 147 Pfam PF07858 Limonene-1,2-epoxide hydrolase catalytic domain 6 124 2.0E-11 T 06-07-2017 IPR013100 Limonene-1,2-epoxide hydrolase BWK49_RS14770 2087d35a519a40d15ef19591bbb7647d 147 Gene3D G3DSA:3.10.450.50 3 129 6.1E-34 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS26320 70664c359406367c7a19ae51aff522ed 275 Pfam PF00722 Glycosyl hydrolases family 16 83 221 9.2E-14 T 06-07-2017 IPR000757 Glycoside hydrolase family 16 GO:0004553|GO:0005975 BWK49_RS26320 70664c359406367c7a19ae51aff522ed 275 Gene3D G3DSA:2.60.120.200 29 275 2.2E-39 T 06-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain BWK49_RS26320 70664c359406367c7a19ae51aff522ed 275 SUPERFAMILY SSF49899 31 275 8.15E-42 T 06-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain BWK49_RS08710 0fc58b45f7fbbbce1adf923616b97613 462 ProSitePatterns PS00571 Amidases signature. 152 183 - T 06-07-2017 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 BWK49_RS08710 0fc58b45f7fbbbce1adf923616b97613 462 Pfam PF01425 Amidase 26 442 4.3E-101 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 BWK49_RS08710 0fc58b45f7fbbbce1adf923616b97613 462 Gene3D G3DSA:3.90.1300.10 4 460 4.1E-116 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 BWK49_RS08710 0fc58b45f7fbbbce1adf923616b97613 462 SUPERFAMILY SSF75304 4 460 2.35E-119 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 BWK49_RS07600 28d3629762dc7e8ee9f6d1ca3418aebe 296 SUPERFAMILY SSF140459 9 83 7.32E-17 T 06-07-2017 BWK49_RS07600 28d3629762dc7e8ee9f6d1ca3418aebe 296 Pfam PF00934 PE family 1 92 2.5E-24 T 06-07-2017 IPR000084 PE-PGRS family, N-terminal BWK49_RS07600 28d3629762dc7e8ee9f6d1ca3418aebe 296 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 212 293 1.3E-19 T 06-07-2017 IPR022171 PPE family, C-terminal BWK49_RS08930 f3441a4b8bc091a5dec6f90c84092935 392 Pfam PF00953 Glycosyl transferase family 4 100 264 4.3E-34 T 06-07-2017 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 BWK49_RS20630 b474385b3ec4199e06ced439141503e3 98 Pfam PF06013 Proteins of 100 residues with WXG 7 90 6.5E-17 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like BWK49_RS20630 b474385b3ec4199e06ced439141503e3 98 Gene3D G3DSA:1.10.287.1060 1 97 1.5E-12 T 06-07-2017 BWK49_RS20630 b474385b3ec4199e06ced439141503e3 98 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 5 93 5.9E-18 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like BWK49_RS20630 b474385b3ec4199e06ced439141503e3 98 SUPERFAMILY SSF140453 4 97 7.72E-19 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like BWK49_RS12120 5fb1e5c154a170121aa06c35d0f4d13e 170 Pfam PF05481 Mycobacterium 19 kDa lipoprotein antigen 14 169 5.3E-15 T 06-07-2017 IPR008691 19kDa lipoprotein antigen GO:0016020 BWK49_RS17720 f2ca725343c940c102b90b3717936bce 259 Pfam PF00106 short chain dehydrogenase 4 190 5.0E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS17720 f2ca725343c940c102b90b3717936bce 259 SUPERFAMILY SSF51735 4 228 2.44E-50 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS17720 f2ca725343c940c102b90b3717936bce 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 4.5E-18 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS17720 f2ca725343c940c102b90b3717936bce 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 4.5E-18 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS17720 f2ca725343c940c102b90b3717936bce 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 4.5E-18 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS17720 f2ca725343c940c102b90b3717936bce 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 139 4.5E-18 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS17720 f2ca725343c940c102b90b3717936bce 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 168 4.5E-18 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS17720 f2ca725343c940c102b90b3717936bce 259 Gene3D G3DSA:3.40.50.720 4 229 3.1E-51 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS17720 f2ca725343c940c102b90b3717936bce 259 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2 180 0.0026 T 06-07-2017 BWK49_RS10095 c31b96d91fc2d2ffead462266763eb7b 139 Pfam PF05423 Mycobacterium membrane protein 3 139 5.2E-51 T 06-07-2017 IPR008693 Transport accessory protein MmpS BWK49_RS14880 2be630a20f7cb73211c7375fdbc2c9d7 241 Pfam PF01904 Protein of unknown function DUF72 20 238 2.8E-64 T 06-07-2017 IPR002763 Protein of unknown function DUF72 BWK49_RS14880 2be630a20f7cb73211c7375fdbc2c9d7 241 Gene3D G3DSA:3.20.20.410 3 241 1.6E-80 T 06-07-2017 IPR002763 Protein of unknown function DUF72 BWK49_RS14880 2be630a20f7cb73211c7375fdbc2c9d7 241 SUPERFAMILY SSF117396 3 241 2.35E-82 T 06-07-2017 IPR002763 Protein of unknown function DUF72 BWK49_RS22990 92b7b924b0804fabb06881e82837f8be 165 Pfam PF12005 Protein of unknown function (DUF3499) 22 162 9.0E-49 T 06-07-2017 IPR021888 Protein of unknown function DUF3499 BWK49_RS04785 e38189d82cfd71d143b7f92a0c23f739 63 SUPERFAMILY SSF54862 1 62 7.29E-10 T 06-07-2017 BWK49_RS04785 e38189d82cfd71d143b7f92a0c23f739 63 PRINTS PR00352 3Fe-4S ferredoxin signature 5 16 1.7E-5 T 06-07-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 BWK49_RS04785 e38189d82cfd71d143b7f92a0c23f739 63 PRINTS PR00352 3Fe-4S ferredoxin signature 16 26 1.7E-5 T 06-07-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 BWK49_RS04785 e38189d82cfd71d143b7f92a0c23f739 63 PRINTS PR00352 3Fe-4S ferredoxin signature 47 59 1.7E-5 T 06-07-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 BWK49_RS04785 e38189d82cfd71d143b7f92a0c23f739 63 Gene3D G3DSA:3.30.70.20 1 63 4.9E-15 T 06-07-2017 BWK49_RS04785 e38189d82cfd71d143b7f92a0c23f739 63 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 5 60 3.9E-10 T 06-07-2017 BWK49_RS21305 5e57539960fbe252d12df0298d138d79 148 SUPERFAMILY SSF55961 1 138 2.5E-37 T 06-07-2017 BWK49_RS21305 5e57539960fbe252d12df0298d138d79 148 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 4 138 1.2E-19 T 06-07-2017 IPR019587 Polyketide cyclase/dehydrase BWK49_RS21305 5e57539960fbe252d12df0298d138d79 148 Gene3D G3DSA:3.30.530.20 3 136 2.9E-15 T 06-07-2017 IPR023393 START-like domain BWK49_RS24540 9555e5c5ea69bc873ffd724f28ca2f50 173 SUPERFAMILY SSF109854 1 167 4.21E-17 T 06-07-2017 BWK49_RS24540 9555e5c5ea69bc873ffd724f28ca2f50 173 Pfam PF12867 DinB superfamily 11 160 2.1E-17 T 06-07-2017 IPR024775 DinB-like domain BWK49_RS01625 987233e6a0a537ee02af4360941c9f01 299 Gene3D G3DSA:3.40.50.1820 14 289 1.9E-59 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS01625 987233e6a0a537ee02af4360941c9f01 299 SUPERFAMILY SSF53474 10 290 7.69E-60 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS01625 987233e6a0a537ee02af4360941c9f01 299 PRINTS PR00412 Epoxide hydrolase signature 118 131 9.6E-6 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS01625 987233e6a0a537ee02af4360941c9f01 299 PRINTS PR00412 Epoxide hydrolase signature 60 75 9.6E-6 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS01625 987233e6a0a537ee02af4360941c9f01 299 PRINTS PR00412 Epoxide hydrolase signature 266 288 9.6E-6 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 BWK49_RS01625 987233e6a0a537ee02af4360941c9f01 299 Pfam PF00561 alpha/beta hydrolase fold 37 278 2.4E-23 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS01625 987233e6a0a537ee02af4360941c9f01 299 PRINTS PR00111 Alpha/beta hydrolase fold signature 104 117 1.9E-6 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS01625 987233e6a0a537ee02af4360941c9f01 299 PRINTS PR00111 Alpha/beta hydrolase fold signature 118 131 1.9E-6 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS01625 987233e6a0a537ee02af4360941c9f01 299 PRINTS PR00111 Alpha/beta hydrolase fold signature 60 75 1.9E-6 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS05055 b42809bf01dddae71dd9fdaac8593bda 146 Gene3D G3DSA:3.10.129.10 7 142 1.3E-29 T 06-07-2017 IPR029069 HotDog domain BWK49_RS05055 b42809bf01dddae71dd9fdaac8593bda 146 Pfam PF03061 Thioesterase superfamily 54 131 1.4E-10 T 06-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 BWK49_RS05055 b42809bf01dddae71dd9fdaac8593bda 146 SUPERFAMILY SSF54637 12 138 1.73E-25 T 06-07-2017 IPR029069 HotDog domain BWK49_RS05055 b42809bf01dddae71dd9fdaac8593bda 146 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 25 137 6.9E-20 T 06-07-2017 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-75105 BWK49_RS26180 ebf7a4f90b98296147b918761be77406 429 Pfam PF07907 YibE/F-like protein 163 398 1.5E-62 T 06-07-2017 IPR012507 YibE/F-like BWK49_RS17615 5bd3ebf9f1029f5863f9a04cd8971648 76 Pfam PF03621 MbtH-like protein 4 54 1.8E-30 T 06-07-2017 IPR005153 MbtH-like protein BWK49_RS17615 5bd3ebf9f1029f5863f9a04cd8971648 76 SMART SM00923 4 54 1.4E-36 T 06-07-2017 IPR005153 MbtH-like protein BWK49_RS17615 5bd3ebf9f1029f5863f9a04cd8971648 76 SUPERFAMILY SSF160582 3 70 7.06E-32 T 06-07-2017 BWK49_RS17615 5bd3ebf9f1029f5863f9a04cd8971648 76 Gene3D G3DSA:3.90.820.10 11 69 9.4E-33 T 06-07-2017 BWK49_RS11250 15eef1aac6a657eff0f5e42dba8dd1f5 507 Pfam PF13556 PucR C-terminal helix-turn-helix domain 446 502 2.1E-17 T 06-07-2017 IPR025736 PucR C-terminal helix-turn-helix domain BWK49_RS05240 3e8a1f57e4bae5fde80d47db16ed0c48 218 Pfam PF01841 Transglutaminase-like superfamily 24 140 6.3E-16 T 06-07-2017 IPR002931 Transglutaminase-like BWK49_RS05240 3e8a1f57e4bae5fde80d47db16ed0c48 218 SUPERFAMILY SSF54001 18 163 1.26E-18 T 06-07-2017 BWK49_RS15585 5991b9ed73d335707a9317e6ed9370e0 533 Gene3D G3DSA:3.40.720.10 2 442 1.6E-121 T 06-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 BWK49_RS15585 5991b9ed73d335707a9317e6ed9370e0 533 Gene3D G3DSA:3.30.1120.10 451 522 3.1E-25 T 06-07-2017 BWK49_RS15585 5991b9ed73d335707a9317e6ed9370e0 533 ProSitePatterns PS00149 Sulfatases signature 2. 104 114 - T 06-07-2017 IPR024607 Sulfatase, conserved site BWK49_RS15585 5991b9ed73d335707a9317e6ed9370e0 533 Pfam PF00884 Sulfatase 4 415 4.4E-77 T 06-07-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 BWK49_RS15585 5991b9ed73d335707a9317e6ed9370e0 533 SUPERFAMILY SSF53649 2 521 1.18E-145 T 06-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 BWK49_RS08400 8f3e7fb2afefefd6225bf7683ae4806b 139 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 55 116 4.6E-17 T 06-07-2017 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal BWK49_RS08400 8f3e7fb2afefefd6225bf7683ae4806b 139 SUPERFAMILY SSF50249 3 124 1.11E-37 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS08400 8f3e7fb2afefefd6225bf7683ae4806b 139 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 17 53 1.3E-15 T 06-07-2017 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal BWK49_RS04480 0f7eeb660751ea0471e0d56177fe5827 884 SUPERFAMILY SSF52540 506 798 1.62E-13 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS04480 0f7eeb660751ea0471e0d56177fe5827 884 Gene3D G3DSA:3.40.50.300 680 771 3.0E-7 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS04480 0f7eeb660751ea0471e0d56177fe5827 884 Gene3D G3DSA:3.40.50.300 502 571 3.0E-7 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS04480 0f7eeb660751ea0471e0d56177fe5827 884 Pfam PF12846 AAA-like domain 502 802 2.4E-23 T 06-07-2017 BWK49_RS25325 e73e9cbccf79db64d2fdcd40ffff7e57 85 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 31 78 2.7E-19 T 06-07-2017 IPR010093 SinI-like, DNA-binding domain GO:0003677 BWK49_RS25325 e73e9cbccf79db64d2fdcd40ffff7e57 85 Pfam PF12728 Helix-turn-helix domain 31 79 6.4E-14 T 06-07-2017 BWK49_RS25325 e73e9cbccf79db64d2fdcd40ffff7e57 85 SUPERFAMILY SSF46955 31 79 2.38E-5 T 06-07-2017 IPR009061 Putative DNA-binding domain BWK49_RS20175 4e504616bb3188e1093d56c51bd27090 394 Pfam PF02666 Phosphatidylserine decarboxylase 168 374 6.7E-39 T 06-07-2017 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 BWK49_RS28205 c1e0097e8b8349a11ca6d880fa200503 383 Gene3D G3DSA:3.90.1200.10 166 339 9.8E-17 T 06-07-2017 BWK49_RS28205 c1e0097e8b8349a11ca6d880fa200503 383 SMART SM00587 143 322 4.5E-4 T 06-07-2017 IPR015897 CHK kinase-like BWK49_RS28205 c1e0097e8b8349a11ca6d880fa200503 383 Pfam PF01636 Phosphotransferase enzyme family 71 314 4.2E-18 T 06-07-2017 IPR002575 Aminoglycoside phosphotransferase BWK49_RS28205 c1e0097e8b8349a11ca6d880fa200503 383 SUPERFAMILY SSF56112 49 346 8.75E-37 T 06-07-2017 IPR011009 Protein kinase-like domain BWK49_RS24210 ec4b6957bc5608b325ee708594645472 308 Gene3D G3DSA:3.20.20.30 3 307 3.0E-74 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS24210 ec4b6957bc5608b325ee708594645472 308 Pfam PF00296 Luciferase-like monooxygenase 15 298 1.1E-51 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS24210 ec4b6957bc5608b325ee708594645472 308 SUPERFAMILY SSF51679 18 307 4.32E-68 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS23400 03ec1c7eac9b38149540fa14a5a9100c 236 Gene3D G3DSA:1.20.120.530 77 212 4.8E-28 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal BWK49_RS23400 03ec1c7eac9b38149540fa14a5a9100c 236 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 63 2.2E-6 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 BWK49_RS23400 03ec1c7eac9b38149540fa14a5a9100c 236 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 33 47 2.2E-6 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 BWK49_RS23400 03ec1c7eac9b38149540fa14a5a9100c 236 Pfam PF07729 FCD domain 84 209 1.6E-21 T 06-07-2017 IPR011711 GntR, C-terminal BWK49_RS23400 03ec1c7eac9b38149540fa14a5a9100c 236 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 73 9.2E-13 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 BWK49_RS23400 03ec1c7eac9b38149540fa14a5a9100c 236 SUPERFAMILY SSF48008 78 215 1.33E-25 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal BWK49_RS23400 03ec1c7eac9b38149540fa14a5a9100c 236 Gene3D G3DSA:1.10.10.10 5 73 4.6E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS23400 03ec1c7eac9b38149540fa14a5a9100c 236 SMART SM00345 15 73 1.3E-11 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 BWK49_RS23400 03ec1c7eac9b38149540fa14a5a9100c 236 SMART SM00895 83 211 5.0E-15 T 06-07-2017 IPR011711 GntR, C-terminal BWK49_RS23400 03ec1c7eac9b38149540fa14a5a9100c 236 SUPERFAMILY SSF46785 10 77 1.29E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS24730 79b3901bde03ac38121dc540ac35f428 226 Pfam PF10738 Probable lipoprotein LpqN 57 225 1.6E-51 T 06-07-2017 IPR019674 Lipoprotein LpqT, predicted BWK49_RS19275 c64d657dd30f5db3e2ce9afc48bc75be 436 Pfam PF09594 Protein of unknown function (DUF2029) 94 329 1.3E-40 T 06-07-2017 IPR018584 Glycosyltransferase family 87 GO:0016758 BWK49_RS25410 ea656e28036b4d85e1722b5e58e0d1a4 174 Pfam PF10698 Protein of unknown function (DUF2505) 7 170 1.4E-52 T 06-07-2017 IPR019639 Protein of unknown function DUF2505 BWK49_RS25410 ea656e28036b4d85e1722b5e58e0d1a4 174 SUPERFAMILY SSF55961 4 156 4.32E-6 T 06-07-2017 BWK49_RS01055 a0e3fe99070bb431673823a84d196ed4 456 Pfam PF13845 Septum formation 99 324 6.0E-77 T 06-07-2017 IPR026004 Septum formation-related domain BWK49_RS26195 ab833760b4deab667569404492fff80d 251 Pfam PF07398 MDMPI C-terminal domain 142 244 4.4E-17 T 06-07-2017 IPR010872 MDMPI C-terminal BWK49_RS26195 ab833760b4deab667569404492fff80d 251 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 9 130 3.0E-23 T 06-07-2017 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 BWK49_RS26195 ab833760b4deab667569404492fff80d 251 SUPERFAMILY SSF109854 6 135 7.63E-10 T 06-07-2017 BWK49_RS26195 ab833760b4deab667569404492fff80d 251 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 9 225 5.0E-30 T 06-07-2017 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type BWK49_RS11730 3a0d9071ad4fe7cb40d7ac024811b7d3 313 Pfam PF10118 Predicted metal-dependent hydrolase 6 202 1.5E-33 T 06-07-2017 IPR016516 Uncharacterised conserved protein UCP07580 BWK49_RS16225 6f7043e6b34e00191545216ff00f8f65 141 SUPERFAMILY SSF54427 12 140 6.74E-30 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS16225 6f7043e6b34e00191545216ff00f8f65 141 Gene3D G3DSA:3.10.450.50 4 140 5.3E-23 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS16225 6f7043e6b34e00191545216ff00f8f65 141 Pfam PF12680 SnoaL-like domain 16 126 9.8E-18 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain BWK49_RS28440 1ff9017f2843325da74fecd10fcbe801 129 SMART SM00418 21 99 1.9E-28 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 BWK49_RS28440 1ff9017f2843325da74fecd10fcbe801 129 Gene3D G3DSA:1.10.10.10 10 97 9.8E-31 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS28440 1ff9017f2843325da74fecd10fcbe801 129 Pfam PF12840 Helix-turn-helix domain 20 78 1.2E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS28440 1ff9017f2843325da74fecd10fcbe801 129 SUPERFAMILY SSF46785 11 94 5.07E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS28440 1ff9017f2843325da74fecd10fcbe801 129 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 23 38 1.8E-12 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 BWK49_RS28440 1ff9017f2843325da74fecd10fcbe801 129 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 55 70 1.8E-12 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 BWK49_RS28440 1ff9017f2843325da74fecd10fcbe801 129 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 70 85 1.8E-12 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 BWK49_RS22040 50c2a065b19fe4a634e9a6ac796bbe2a 99 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 6 93 1.6E-24 T 06-07-2017 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 BWK49_RS22040 50c2a065b19fe4a634e9a6ac796bbe2a 99 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 1 99 19.809 T 06-07-2017 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 BWK49_RS23910 53c75a82b47f739f80615ebb40f2f389 116 Gene3D G3DSA:3.10.450.50 2 83 1.6E-10 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS23910 53c75a82b47f739f80615ebb40f2f389 116 SUPERFAMILY SSF54427 2 104 1.84E-17 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS23910 53c75a82b47f739f80615ebb40f2f389 116 Pfam PF12680 SnoaL-like domain 11 104 5.9E-10 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain BWK49_RS18610 322d6b10e1741d0df8c1f28f7917076d 414 Pfam PF02618 YceG-like family 83 402 5.2E-58 T 06-07-2017 IPR003770 Uncharacterised protein family UPF0755, YceG-like BWK49_RS18610 322d6b10e1741d0df8c1f28f7917076d 414 Gene3D G3DSA:3.30.160.60 375 401 1.5E-4 T 06-07-2017 IPR013087 Zinc finger C2H2-type/integrase DNA-binding domain GO:0003676 BWK49_RS18610 322d6b10e1741d0df8c1f28f7917076d 414 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 46 399 1.8E-35 T 06-07-2017 IPR003770 Uncharacterised protein family UPF0755, YceG-like BWK49_RS12805 f317c064cc6b1b6df40eb097ac0c93dc 531 SUPERFAMILY SSF51905 7 332 3.1E-37 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS12805 f317c064cc6b1b6df40eb097ac0c93dc 531 SUPERFAMILY SSF51905 467 508 3.1E-37 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS12805 f317c064cc6b1b6df40eb097ac0c93dc 531 Pfam PF01593 Flavin containing amine oxidoreductase 18 505 1.5E-17 T 06-07-2017 IPR002937 Amine oxidase GO:0016491|GO:0055114 BWK49_RS12805 f317c064cc6b1b6df40eb097ac0c93dc 531 Gene3D G3DSA:3.50.50.60 7 121 1.6E-30 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS12805 f317c064cc6b1b6df40eb097ac0c93dc 531 Gene3D G3DSA:3.50.50.60 224 360 1.6E-30 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS28455 5a4a9f8203f111ffce8f610702aedec9 1011 Pfam PF13700 Domain of unknown function (DUF4158) 5 175 1.6E-35 T 06-07-2017 IPR025296 Domain of unknown function DUF4158 BWK49_RS28455 5a4a9f8203f111ffce8f610702aedec9 1011 Pfam PF01526 Tn3 transposase DDE domain 601 990 5.9E-135 T 06-07-2017 IPR002513 Tn3 transposase DDE domain GO:0004803|GO:0006313 BWK49_RS00215 e3de64a505ce62a3c6f29e55c5ade7c6 485 Pfam PF10774 Domain of unknown function (DUF4226) 85 194 1.1E-35 T 06-07-2017 IPR019710 Protein of unknown function DUF4226 BWK49_RS09355 0f483e1dba36e9399ff30f351e90db35 128 Gene3D G3DSA:1.10.630.10 16 123 8.3E-15 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS09355 0f483e1dba36e9399ff30f351e90db35 128 SUPERFAMILY SSF48264 17 123 3.01E-12 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS04855 359b3db2f45c0ab273be4c1b5c774293 149 Gene3D G3DSA:3.30.530.20 9 145 9.1E-11 T 06-07-2017 IPR023393 START-like domain BWK49_RS04855 359b3db2f45c0ab273be4c1b5c774293 149 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 9 139 1.7E-11 T 06-07-2017 IPR019587 Polyketide cyclase/dehydrase BWK49_RS04855 359b3db2f45c0ab273be4c1b5c774293 149 SUPERFAMILY SSF55961 1 143 2.66E-21 T 06-07-2017 BWK49_RS03975 7f20740b6d5e1a8cb5d3f01e1733d6f1 187 Pfam PF06736 Protein of unknown function (DUF1211) 2 84 5.6E-26 T 06-07-2017 IPR010617 Endosomal/lysomomal potassium channel TMEM175 GO:0005267 BWK49_RS22330 8c2926276ed75d59acfc623e2ffcb8ae 96 Pfam PF05360 yiaA/B two helix domain 14 66 2.0E-16 T 06-07-2017 IPR008024 YiaAB two helix BWK49_RS23430 45b1a76f67c435d8d8200d7b94e669e2 156 SUPERFAMILY SSF81343 25 152 1.44E-32 T 06-07-2017 BWK49_RS23430 45b1a76f67c435d8d8200d7b94e669e2 156 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 29 135 1.0E-16 T 06-07-2017 IPR000701 Succinate dehydrogenase/Fumarate reductase, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 BWK49_RS23430 45b1a76f67c435d8d8200d7b94e669e2 156 Gene3D G3DSA:1.20.950.10 21 154 7.0E-47 T 06-07-2017 BWK49_RS25945 3c42c59d160f5dabbdb18e68faef2eb6 123 Pfam PF11255 Protein of unknown function (DUF3054) 10 112 2.2E-34 T 06-07-2017 IPR021414 Protein of unknown function DUF3054 BWK49_RS03115 295ee26f504ca9dbcfac38651baab6d5 112 ProDom PD026347 LSR2-LIKE LSR2 ANTIGEN IMMUNE PRECURSOR RESPONSE SIGNAL PLASMID LYSYL GP61 1 108 1.0E-42 T 06-07-2017 IPR024412 Lsr2 BWK49_RS03115 295ee26f504ca9dbcfac38651baab6d5 112 Pfam PF11774 Lsr2 1 111 2.1E-43 T 06-07-2017 IPR024412 Lsr2 BWK49_RS00155 38e5a5b9174e176b132b1e2af23035c2 87 Gene3D G3DSA:1.10.1200.10 11 81 3.2E-15 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS00155 38e5a5b9174e176b132b1e2af23035c2 87 Pfam PF00550 Phosphopantetheine attachment site 14 79 2.0E-11 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS00155 38e5a5b9174e176b132b1e2af23035c2 87 SUPERFAMILY SSF47336 12 81 8.51E-14 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain BWK49_RS10710 7c57c0fc4002b533f4ce1e71138e4821 413 Pfam PF01554 MatE 262 411 4.9E-19 T 06-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 BWK49_RS10710 7c57c0fc4002b533f4ce1e71138e4821 413 Pfam PF01554 MatE 25 194 5.6E-9 T 06-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 BWK49_RS10710 7c57c0fc4002b533f4ce1e71138e4821 413 TIGRFAM TIGR00797 matE: MATE efflux family protein 25 412 2.2E-44 T 06-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 BWK49_RS05380 a0b5e4314b717dbb52a2217a3fa6e637 450 Gene3D G3DSA:3.30.420.10 274 436 1.3E-8 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS05380 a0b5e4314b717dbb52a2217a3fa6e637 450 SUPERFAMILY SSF53098 272 438 6.37E-22 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS05380 a0b5e4314b717dbb52a2217a3fa6e637 450 Pfam PF00665 Integrase core domain 274 394 3.2E-8 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 BWK49_RS05380 a0b5e4314b717dbb52a2217a3fa6e637 450 Pfam PF13936 Helix-turn-helix domain 64 104 1.5E-16 T 06-07-2017 IPR025246 Transposase IS30-like HTH domain BWK49_RS25070 976497c2375030aeaf995e65aeb6dd79 100 Pfam PF11829 Protein of unknown function (DUF3349) 4 91 6.4E-33 T 06-07-2017 IPR021784 Protein of unknown function DUF3349 BWK49_RS25495 319f72c498d67a10457e5c40d8c1950f 186 Gene3D G3DSA:1.20.1290.10 37 184 3.7E-27 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 BWK49_RS25495 319f72c498d67a10457e5c40d8c1950f 186 SUPERFAMILY SSF69118 6 183 2.75E-29 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 BWK49_RS25495 319f72c498d67a10457e5c40d8c1950f 186 Pfam PF02627 Carboxymuconolactone decarboxylase family 47 110 4.1E-13 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 BWK49_RS00850 5a56a7466b2d9e06c04892062d6c0f34 390 Pfam PF00823 PPE family 9 165 3.0E-26 T 06-07-2017 IPR000030 PPE family BWK49_RS00850 5a56a7466b2d9e06c04892062d6c0f34 390 SUPERFAMILY SSF140459 6 175 2.25E-29 T 06-07-2017 BWK49_RS22200 df8253745ce34f1ff7167f647ca281b3 314 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 173 294 1.2E-13 T 06-07-2017 IPR007182 Na+/H+ antiporter MnhB subunit-related protein BWK49_RS01960 995fe12006f2235e1b419ffc611ceb63 147 Pfam PF07883 Cupin domain 60 129 1.5E-16 T 06-07-2017 IPR013096 Cupin 2, conserved barrel BWK49_RS01960 995fe12006f2235e1b419ffc611ceb63 147 SUPERFAMILY SSF51182 30 137 2.74E-22 T 06-07-2017 IPR011051 RmlC-like cupin domain BWK49_RS01960 995fe12006f2235e1b419ffc611ceb63 147 Gene3D G3DSA:2.60.120.10 34 140 2.0E-20 T 06-07-2017 IPR014710 RmlC-like jelly roll fold BWK49_RS05445 801740f82166ff4a032cda6560661551 70 Pfam PF00872 Transposase, Mutator family 1 36 4.1E-7 T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 BWK49_RS18665 a8d9709bf7a49aaee7df84f358610d64 351 PIRSF PIRSF012641 1 350 5.8E-148 T 06-07-2017 IPR031321 Uncharacterised conserved protein UCP012641, putative zinc-binding metallo-peptidase BWK49_RS18665 a8d9709bf7a49aaee7df84f358610d64 351 Pfam PF15887 Putative zinc-binding metallo-peptidase 99 334 8.2E-101 T 06-07-2017 IPR031321 Uncharacterised conserved protein UCP012641, putative zinc-binding metallo-peptidase BWK49_RS18665 a8d9709bf7a49aaee7df84f358610d64 351 Pfam PF10005 zinc-ribbon domain 4 92 1.3E-24 T 06-07-2017 IPR011201 Zinc-ribbon domain, bacteria BWK49_RS25600 0b0a7ca80c64f307ade99cde099d9462 214 SUPERFAMILY SSF140459 6 173 2.62E-60 T 06-07-2017 BWK49_RS25600 0b0a7ca80c64f307ade99cde099d9462 214 Pfam PF00823 PPE family 8 164 3.4E-60 T 06-07-2017 IPR000030 PPE family BWK49_RS15930 343507a7b0d64ae79314a4759fd6bfde 241 Pfam PF01872 RibD C-terminal domain 28 202 1.3E-23 T 06-07-2017 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 BWK49_RS15930 343507a7b0d64ae79314a4759fd6bfde 241 SUPERFAMILY SSF53597 28 239 3.93E-30 T 06-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 BWK49_RS15930 343507a7b0d64ae79314a4759fd6bfde 241 Gene3D G3DSA:3.40.430.10 27 241 8.6E-47 T 06-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 BWK49_RS15305 0b538319473d990e33afdeb07d29883a 505 TIGRFAM TIGR03919 T7SS_EccB: type VII secretion protein EccB 18 481 2.5E-148 T 06-07-2017 IPR007795 Type VII secretion system EccB BWK49_RS15305 0b538319473d990e33afdeb07d29883a 505 Pfam PF05108 Type VII secretion system ESX-1, transport TM domain B 16 493 2.3E-148 T 06-07-2017 IPR007795 Type VII secretion system EccB BWK49_RS01260 e69f70cc4332d6e9f502978e45006545 486 Pfam PF02720 Domain of unknown function (DUF222) 26 329 4.4E-72 T 06-07-2017 IPR003870 Domain of unknown function DUF222 BWK49_RS01260 e69f70cc4332d6e9f502978e45006545 486 SMART SM00507 320 371 1.6E-9 T 06-07-2017 IPR003615 HNH nuclease BWK49_RS20710 0ad8397c3b6ca2687f87665ddf770f34 245 Pfam PF06912 Protein of unknown function (DUF1275) 21 211 2.3E-22 T 06-07-2017 IPR010699 Protein of unknown function DUF1275 BWK49_RS00320 03329e846c7c8e3571a1a5e1ebb10f6e 402 Pfam PF06742 Protein of unknown function (DUF1214) 90 178 4.7E-5 T 06-07-2017 IPR010621 Domain of unknown function DUF1214 BWK49_RS21630 c8c0ad493daa55b01bf83309f84698f2 125 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 10 123 17.443 T 06-07-2017 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 BWK49_RS21630 c8c0ad493daa55b01bf83309f84698f2 125 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 13 118 2.4E-21 T 06-07-2017 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 BWK49_RS26585 f49014dd9aa3d1deb3682f04b9e3c627 340 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 46 288 4.9E-31 T 06-07-2017 IPR018713 Domain of unknown function DUF2236 BWK49_RS15250 971f61a542dfc91d111c9e78d2895144 99 SUPERFAMILY SSF140459 8 83 9.94E-26 T 06-07-2017 BWK49_RS15250 971f61a542dfc91d111c9e78d2895144 99 Pfam PF00934 PE family 1 93 2.4E-35 T 06-07-2017 IPR000084 PE-PGRS family, N-terminal BWK49_RS04735 cf6948c467f3537e25ad00000720c59f 185 Pfam PF00872 Transposase, Mutator family 2 148 3.7E-15 T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 BWK49_RS02585 8794f18abe2cbd24bb1045b84300efcb 490 PIRSF PIRSF012666 1 490 3.6E-237 T 06-07-2017 IPR016602 Uncharacterised conserved protein UCP012666 BWK49_RS02585 8794f18abe2cbd24bb1045b84300efcb 490 SUPERFAMILY SSF55931 36 280 7.16E-43 T 06-07-2017 BWK49_RS02585 8794f18abe2cbd24bb1045b84300efcb 490 SUPERFAMILY SSF55931 311 457 7.16E-43 T 06-07-2017 BWK49_RS25035 e24afc4db7e04842a9a645573f75ebd3 307 SUPERFAMILY SSF51430 18 293 1.24E-59 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain BWK49_RS25035 e24afc4db7e04842a9a645573f75ebd3 307 PRINTS PR00069 Aldo-keto reductase signature 226 250 2.0E-8 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 BWK49_RS25035 e24afc4db7e04842a9a645573f75ebd3 307 PRINTS PR00069 Aldo-keto reductase signature 152 169 2.0E-8 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 BWK49_RS25035 e24afc4db7e04842a9a645573f75ebd3 307 PRINTS PR00069 Aldo-keto reductase signature 44 68 2.0E-8 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 BWK49_RS25035 e24afc4db7e04842a9a645573f75ebd3 307 Pfam PF00248 Aldo/keto reductase family 20 292 6.9E-43 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain BWK49_RS25035 e24afc4db7e04842a9a645573f75ebd3 307 Gene3D G3DSA:3.20.20.100 18 294 4.5E-59 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain BWK49_RS05980 d7c7c91d3135cb901e8f1557257f8508 348 Pfam PF13439 Glycosyltransferase Family 4 30 142 1.4E-6 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 BWK49_RS05980 d7c7c91d3135cb901e8f1557257f8508 348 SUPERFAMILY SSF53756 51 312 9.42E-12 T 06-07-2017 BWK49_RS01245 75efdb82d2c116beea96af1ee9547311 463 Gene3D G3DSA:3.30.465.10 77 195 5.6E-28 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 BWK49_RS01245 75efdb82d2c116beea96af1ee9547311 463 Pfam PF04030 D-arabinono-1,4-lactone oxidase 396 459 8.8E-8 T 06-07-2017 IPR007173 D-arabinono-1,4-lactone oxidase GO:0003885|GO:0016020|GO:0055114 BWK49_RS01245 75efdb82d2c116beea96af1ee9547311 463 Pfam PF01565 FAD binding domain 26 160 4.6E-26 T 06-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 BWK49_RS01245 75efdb82d2c116beea96af1ee9547311 463 SUPERFAMILY SSF56176 10 195 1.73E-38 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 BWK49_RS04085 e705fc9755da5fc06cfcef19e15ef0da 212 Pfam PF08768 Domain of unknown function (DUF1794) 51 209 3.3E-42 T 06-07-2017 IPR014878 Domain of unknown function DUF1794 BWK49_RS04085 e705fc9755da5fc06cfcef19e15ef0da 212 SUPERFAMILY SSF50814 46 209 1.94E-33 T 06-07-2017 IPR011038 Calycin-like BWK49_RS04085 e705fc9755da5fc06cfcef19e15ef0da 212 Hamap MF_01297 UPF0678 fatty acid-binding protein-like protein . 43 211 29.375 T 06-07-2017 IPR022939 Uncharacterised protein family UPF0678 BWK49_RS28250 b6c6eecb7b5cce8a937853f78bae1b35 495 Pfam PF05108 Type VII secretion system ESX-1, transport TM domain B 5 479 6.1E-150 T 06-07-2017 IPR007795 Type VII secretion system EccB BWK49_RS28250 b6c6eecb7b5cce8a937853f78bae1b35 495 TIGRFAM TIGR03919 T7SS_EccB: type VII secretion protein EccB 6 467 6.1E-147 T 06-07-2017 IPR007795 Type VII secretion system EccB BWK49_RS09645 5e1981e23e0c7f8bc8aaa0cbacf65ddf 75 Pfam PF12277 Protein of unknown function (DUF3618) 3 49 4.7E-18 T 06-07-2017 IPR022062 Protein of unknown function DUF3618 BWK49_RS18040 537acb6e77554f833e7020c42eecbed2 144 SUPERFAMILY SSF51182 25 133 2.18E-18 T 06-07-2017 IPR011051 RmlC-like cupin domain BWK49_RS18040 537acb6e77554f833e7020c42eecbed2 144 Pfam PF07883 Cupin domain 55 127 1.8E-12 T 06-07-2017 IPR013096 Cupin 2, conserved barrel BWK49_RS18040 537acb6e77554f833e7020c42eecbed2 144 Gene3D G3DSA:2.60.120.10 22 128 2.8E-21 T 06-07-2017 IPR014710 RmlC-like jelly roll fold BWK49_RS28695 9a34ec7e380c887536433dba976a7372 217 Pfam PF13701 Transposase DDE domain group 1 35 165 5.2E-10 T 06-07-2017 IPR025668 Transposase DDE domain BWK49_RS14055 c053c6994e5ba4a62e968608dd09e8c6 229 Pfam PF01965 DJ-1/PfpI family 27 224 4.0E-16 T 06-07-2017 IPR002818 DJ-1/PfpI BWK49_RS14055 c053c6994e5ba4a62e968608dd09e8c6 229 Gene3D G3DSA:3.40.50.880 1 228 8.4E-79 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like BWK49_RS14055 c053c6994e5ba4a62e968608dd09e8c6 229 SUPERFAMILY SSF52317 1 227 6.17E-70 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like BWK49_RS13730 e63beee43d496d2262ff38bc544a16a6 129 Pfam PF11903 ParD-like antitoxin of type II bacterial toxin-antitoxin system 7 106 6.4E-22 T 06-07-2017 IPR021831 ParD-like antitoxin of type II bacterial toxin-antitoxin system BWK49_RS12200 a851d28f9b09b168f0565ca11aeae8d9 118 SUPERFAMILY SSF47598 68 106 2.49E-8 T 06-07-2017 IPR010985 Ribbon-helix-helix GO:0006355 BWK49_RS12200 a851d28f9b09b168f0565ca11aeae8d9 118 Pfam PF05534 HicB family 60 103 6.0E-19 T 06-07-2017 IPR008651 Uncharacterised protein family HicB BWK49_RS12200 a851d28f9b09b168f0565ca11aeae8d9 118 SUPERFAMILY SSF143100 3 68 3.01E-9 T 06-07-2017 BWK49_RS12200 a851d28f9b09b168f0565ca11aeae8d9 118 Gene3D G3DSA:1.10.1220.10 72 104 7.2E-6 T 06-07-2017 IPR013321 Arc-type ribbon-helix-helix GO:0006355 BWK49_RS13745 32a37f15d9fe1d1bcff1c7f54ef73fc0 189 SUPERFAMILY SSF52499 5 186 6.54E-48 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 BWK49_RS13745 32a37f15d9fe1d1bcff1c7f54ef73fc0 189 Pfam PF00857 Isochorismatase family 6 185 1.9E-31 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 BWK49_RS13745 32a37f15d9fe1d1bcff1c7f54ef73fc0 189 Gene3D G3DSA:3.40.50.850 5 186 4.9E-57 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 BWK49_RS03595 ec3ea19af44367d2ba17315a89940ef9 254 Pfam PF02405 Permease MlaE 36 247 1.8E-60 T 06-07-2017 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 BWK49_RS26445 b00dbf3c8c9a9f5deccc40b35652726a 102 ProDom PD195452 PE FAMILY PRECURSOR PE-FAMILY SIGNAL PE15 PE_1 47 81 2.0E-10 T 06-07-2017 BWK49_RS26445 b00dbf3c8c9a9f5deccc40b35652726a 102 Pfam PF00934 PE family 3 92 2.2E-21 T 06-07-2017 IPR000084 PE-PGRS family, N-terminal BWK49_RS26445 b00dbf3c8c9a9f5deccc40b35652726a 102 SUPERFAMILY SSF140459 7 73 1.12E-13 T 06-07-2017 BWK49_RS19645 65f7a1c69394cfa6a1d945eb3e5d01dd 104 Pfam PF03992 Antibiotic biosynthesis monooxygenase 2 71 2.2E-18 T 06-07-2017 IPR007138 Antibiotic biosynthesis monooxygenase domain BWK49_RS19645 65f7a1c69394cfa6a1d945eb3e5d01dd 104 SUPERFAMILY SSF54909 1 95 5.37E-25 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel BWK49_RS19645 65f7a1c69394cfa6a1d945eb3e5d01dd 104 Gene3D G3DSA:3.30.70.900 1 92 4.7E-25 T 06-07-2017 BWK49_RS05310 ed421770ee1a55e9c339a7dbca61627c 444 Pfam PF05598 Transposase domain (DUF772) 55 122 2.5E-18 T 06-07-2017 IPR008490 Transposase InsH, N-terminal BWK49_RS05310 ed421770ee1a55e9c339a7dbca61627c 444 Pfam PF01609 Transposase DDE domain 271 442 1.9E-20 T 06-07-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 BWK49_RS06955 af103c8f1d61db5a3738d8bf5a10fcfb 106 Pfam PF01817 Chorismate mutase type II 34 86 8.8E-9 T 06-07-2017 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 BWK49_RS06955 af103c8f1d61db5a3738d8bf5a10fcfb 106 SUPERFAMILY SSF48600 25 87 1.28E-12 T 06-07-2017 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 BWK49_RS06955 af103c8f1d61db5a3738d8bf5a10fcfb 106 SMART SM00830 34 96 4.8E-5 T 06-07-2017 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 BWK49_RS06955 af103c8f1d61db5a3738d8bf5a10fcfb 106 TIGRFAM TIGR01808 CM_M_hiGC-arch: chorismate mutase 30 102 5.2E-38 T 06-07-2017 IPR010958 Chorismate mutase, high GC Gram-positive bacteria/archaeal BWK49_RS06955 af103c8f1d61db5a3738d8bf5a10fcfb 106 Gene3D G3DSA:1.20.59.10 23 82 1.1E-13 T 06-07-2017 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 BWK49_RS22665 cefb166d125c4d5902b7e3184cbc51dd 103 SUPERFAMILY SSF46767 6 82 4.45E-16 T 06-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 BWK49_RS22665 cefb166d125c4d5902b7e3184cbc51dd 103 Gene3D G3DSA:1.10.10.10 9 84 5.1E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS22665 cefb166d125c4d5902b7e3184cbc51dd 103 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 10 82 7.1E-18 T 06-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 BWK49_RS15690 0212ca2a357250019aff0e04a8fb0389 350 Gene3D G3DSA:3.40.50.1820 80 325 5.3E-53 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS15690 0212ca2a357250019aff0e04a8fb0389 350 SUPERFAMILY SSF53474 82 326 2.75E-46 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS15690 0212ca2a357250019aff0e04a8fb0389 350 Pfam PF07859 alpha/beta hydrolase fold 98 303 9.5E-45 T 06-07-2017 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 BWK49_RS15690 0212ca2a357250019aff0e04a8fb0389 350 ProSitePatterns PS01174 Lipolytic enzymes "G-D-X-G" family, putative serine active site. 166 178 - T 06-07-2017 IPR033140 Lipase, GDXG, putative serine active site BWK49_RS05010 730ac229469eba9d927528df80e7126a 394 SUPERFAMILY SSF47240 155 310 7.39E-21 T 06-07-2017 IPR009078 Ferritin-like superfamily BWK49_RS16345 47dae7cbfd9a87ed6e28b84740e676cd 627 Gene3D G3DSA:3.40.50.880 194 333 1.2E-4 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like BWK49_RS13305 4af70241a727ce49e3808b99380fe7b6 413 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 166 260 1.2E-7 T 06-07-2017 IPR024516 Mammalian cell entry, C-terminal BWK49_RS13305 4af70241a727ce49e3808b99380fe7b6 413 Pfam PF02470 MlaD protein 41 115 3.0E-9 T 06-07-2017 IPR003399 Mce/MlaD BWK49_RS02185 653efbcbadc78869765f07d51b5f9246 199 SUPERFAMILY SSF159275 10 199 2.35E-52 T 06-07-2017 BWK49_RS02185 653efbcbadc78869765f07d51b5f9246 199 Pfam PF06475 Putative glycolipid-binding 16 198 1.9E-52 T 06-07-2017 IPR009467 Putative glycolipid-binding protein BWK49_RS18400 ee9a9bb9bc0f69c550ffb957e1bf196e 651 Gene3D G3DSA:3.40.50.300 161 247 8.4E-4 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS18400 ee9a9bb9bc0f69c550ffb957e1bf196e 651 Hamap MF_00983 Probable primosomal protein N' [priA]. 1 650 21.571 T 06-07-2017 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 BWK49_RS09410 f60acae79eab0a3902e56e69291b8c2a 373 SUPERFAMILY SSF53474 136 371 7.62E-20 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS09410 f60acae79eab0a3902e56e69291b8c2a 373 Gene3D G3DSA:3.40.50.1820 306 369 1.3E-18 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS09410 f60acae79eab0a3902e56e69291b8c2a 373 Gene3D G3DSA:3.40.50.1820 148 270 1.3E-18 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS09410 f60acae79eab0a3902e56e69291b8c2a 373 Pfam PF10503 Esterase PHB depolymerase 149 263 2.2E-5 T 06-07-2017 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 BWK49_RS20090 e082f8264d99392eadc9c4d96956c86f 84 Pfam PF10939 Protein of unknown function (DUF2631) 2 65 7.8E-29 T 06-07-2017 IPR024341 Protein of unknown function DUF2631 BWK49_RS20090 e082f8264d99392eadc9c4d96956c86f 84 ProDom PD069408 TRANSMEMBRANE MEMBRANE RV2876/MT2944.1 CGL2017/CG2211 ML1584 POSSIBLE P20 1 84 2.0E-35 T 06-07-2017 IPR024341 Protein of unknown function DUF2631 BWK49_RS26315 70172e3f7332f2490c52d4ae5bf2ffd9 511 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 72 223 2.8E-10 T 06-07-2017 BWK49_RS23775 ab4d32a23b3d5966bebc4fd603421a7d 202 Pfam PF16751 Anti-sigma-D factor RsdA to sigma factor binding region 4 49 2.9E-18 T 06-07-2017 IPR031928 Anti-sigma-D factor RsdA, sigma factor binding region BWK49_RS06715 a53263312643cc9d46489c9a0d3a60f8 87 Pfam PF10944 Protein of unknown function (DUF2630) 8 86 4.5E-33 T 06-07-2017 IPR020311 Uncharacterised protein family, Rv0898c BWK49_RS06715 a53263312643cc9d46489c9a0d3a60f8 87 ProDom PD062385 SCO7189 RV0898C/MT0921.1 MB0922C 16 86 6.0E-31 T 06-07-2017 IPR020311 Uncharacterised protein family, Rv0898c BWK49_RS13295 63685e5a99f183f226620e5edbcfeb0d 224 Pfam PF09976 Tetratricopeptide repeat-like domain 68 151 4.2E-6 T 06-07-2017 IPR018704 Tetratricopeptide repeat-like domain Reactome: R-HSA-192823|Reactome: R-HSA-381038 BWK49_RS21690 2a49d2c5a8d17285b272fe97c4680e93 334 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 47 277 2.6E-35 T 06-07-2017 IPR018713 Domain of unknown function DUF2236 BWK49_RS07510 6a9e92c96ed42d0af8c4d9e14561cb49 242 Pfam PF13406 Transglycosylase SLT domain 159 200 4.7E-7 T 06-07-2017 IPR031304 Transglycosylase SLT domain 2 BWK49_RS07510 6a9e92c96ed42d0af8c4d9e14561cb49 242 Gene3D G3DSA:1.10.530.10 159 227 1.8E-10 T 06-07-2017 BWK49_RS07510 6a9e92c96ed42d0af8c4d9e14561cb49 242 Gene3D G3DSA:1.10.530.10 92 123 1.8E-10 T 06-07-2017 BWK49_RS07510 6a9e92c96ed42d0af8c4d9e14561cb49 242 SUPERFAMILY SSF53955 65 241 2.11E-34 T 06-07-2017 IPR023346 Lysozyme-like domain BWK49_RS18850 2772f8ce46e4e5efff8d35239db781c8 203 Pfam PF13785 Domain of unknown function (DUF4178) 55 189 2.1E-33 T 06-07-2017 IPR025235 Domain of unknown function DUF4178 BWK49_RS02155 a11d6766ca6d6128b2f28c77df9c31b9 350 SUPERFAMILY SSF56112 11 316 1.05E-46 T 06-07-2017 IPR011009 Protein kinase-like domain BWK49_RS02155 a11d6766ca6d6128b2f28c77df9c31b9 350 Pfam PF01636 Phosphotransferase enzyme family 33 263 7.5E-42 T 06-07-2017 IPR002575 Aminoglycoside phosphotransferase BWK49_RS02155 a11d6766ca6d6128b2f28c77df9c31b9 350 Gene3D G3DSA:3.90.1200.10 132 301 3.0E-25 T 06-07-2017 BWK49_RS27515 537d5ef05e3e8d76d6c7a53e8fd3518c 275 Gene3D G3DSA:3.40.50.150 7 204 1.9E-36 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS27515 537d5ef05e3e8d76d6c7a53e8fd3518c 275 Pfam PF04072 Leucine carboxyl methyltransferase 17 171 8.1E-17 T 06-07-2017 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 BWK49_RS27515 537d5ef05e3e8d76d6c7a53e8fd3518c 275 SUPERFAMILY SSF53335 9 241 8.14E-58 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS27515 537d5ef05e3e8d76d6c7a53e8fd3518c 275 PIRSF PIRSF028177 1 268 3.3E-74 T 06-07-2017 IPR016874 Tetracenomycin polyketide synthesis O-methyltransferase TcmP GO:0017000|GO:1901106 BWK49_RS03205 947c22e46c59ea01eb471efa6999815a 308 Gene3D G3DSA:3.60.15.10 21 257 8.1E-20 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS03205 947c22e46c59ea01eb471efa6999815a 308 SUPERFAMILY SSF56281 28 266 5.46E-22 T 06-07-2017 IPR001279 Metallo-beta-lactamase BWK49_RS07745 8b68b087bd0a38b78fbca32343fdf591 144 Pfam PF14155 Domain of unknown function (DUF4307) 23 133 1.5E-36 T 06-07-2017 IPR025443 Protein of unknown function DUF4307 BWK49_RS27205 71ae1fa590ebd7accbc2289aec0bdbed 474 Pfam PF12051 Protein of unknown function (DUF3533) 29 403 1.7E-46 T 06-07-2017 IPR022703 Domain of unknown function DUF3533 BWK49_RS16095 064e2708fc3b2c7305bc11fe359292a3 246 Pfam PF06912 Protein of unknown function (DUF1275) 22 212 5.6E-22 T 06-07-2017 IPR010699 Protein of unknown function DUF1275 BWK49_RS05645 1133f832d87aa928aed5e8e21bc4fdfa 83 Pfam PF01402 Ribbon-helix-helix protein, copG family 9 40 1.1E-4 T 06-07-2017 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 BWK49_RS05645 1133f832d87aa928aed5e8e21bc4fdfa 83 SUPERFAMILY SSF47598 2 65 2.54E-16 T 06-07-2017 IPR010985 Ribbon-helix-helix GO:0006355 BWK49_RS17420 38e1aff1c1270cb7867c3c26071d3359 169 SUPERFAMILY SSF55144 1 129 2.79E-10 T 06-07-2017 IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase BWK49_RS17420 38e1aff1c1270cb7867c3c26071d3359 169 Pfam PF13563 2'-5' RNA ligase superfamily 18 141 1.8E-7 T 06-07-2017 BWK49_RS17420 38e1aff1c1270cb7867c3c26071d3359 169 Gene3D G3DSA:3.90.1140.10 10 136 2.5E-5 T 06-07-2017 IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase BWK49_RS24090 73e62fde18d480539967349f802ffac6 232 Gene3D G3DSA:2.102.10.10 78 229 2.1E-27 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS24090 73e62fde18d480539967349f802ffac6 232 SUPERFAMILY SSF50022 125 228 3.4E-26 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS24090 73e62fde18d480539967349f802ffac6 232 Pfam PF00355 Rieske [2Fe-2S] domain 127 202 2.7E-16 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 BWK49_RS08570 7942b259f5048d970f98ea6936190267 175 Gene3D G3DSA:1.20.1250.20 96 137 9.0E-4 T 06-07-2017 BWK49_RS27370 1eaefd9c903c4dfed20e0bb115ce0924 306 Gene3D G3DSA:3.20.20.30 1 303 1.8E-69 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS27370 1eaefd9c903c4dfed20e0bb115ce0924 306 TIGRFAM TIGR03619 F420_Rv2161c: probable F420-dependent oxidoreductase, Rv2161c family 26 282 6.6E-81 T 06-07-2017 IPR019921 Luciferase-like, F420-dependent oxidoreductase, Rv2161c, predicted BWK49_RS27370 1eaefd9c903c4dfed20e0bb115ce0924 306 SUPERFAMILY SSF51679 1 303 1.31E-63 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS27370 1eaefd9c903c4dfed20e0bb115ce0924 306 Pfam PF00296 Luciferase-like monooxygenase 1 223 8.1E-48 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS05815 8aa8f97e0668952d4de670ac3198f0b9 104 SUPERFAMILY SSF54909 3 84 1.61E-10 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel BWK49_RS08665 0c043cf3f53687e2c8304e4d4851a9e0 379 Pfam PF01757 Acyltransferase family 23 372 1.1E-31 T 06-07-2017 IPR002656 Acyltransferase 3 GO:0016747 BWK49_RS25910 1827f688c701dc290269b5a09c690980 284 SUPERFAMILY SSF52980 174 273 6.43E-6 T 06-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 BWK49_RS22035 2f678d924668585673a424afae5a4e4e 262 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 31 176 3.2E-28 T 06-07-2017 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS02275 8c0b9ca9b0bf23ebf3e265aee6d9c49b 394 Gene3D G3DSA:3.40.50.10540 303 394 8.1E-101 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS02275 8c0b9ca9b0bf23ebf3e265aee6d9c49b 394 Gene3D G3DSA:3.40.50.10540 1 213 8.1E-101 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS02275 8c0b9ca9b0bf23ebf3e265aee6d9c49b 394 Gene3D G3DSA:3.30.1540.10 219 302 1.8E-22 T 06-07-2017 BWK49_RS02275 8c0b9ca9b0bf23ebf3e265aee6d9c49b 394 Pfam PF02515 CoA-transferase family III 2 370 9.0E-114 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 BWK49_RS02275 8c0b9ca9b0bf23ebf3e265aee6d9c49b 394 SUPERFAMILY SSF89796 1 394 1.83E-121 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS05660 3105cab973512782624e79b8ba9dc6b1 223 Pfam PF08808 RES domain 10 183 2.5E-13 T 06-07-2017 IPR014914 RES domain BWK49_RS23290 a3b5df6510f2408ad56230f855785533 382 Pfam PF00823 PPE family 6 160 9.7E-55 T 06-07-2017 IPR000030 PPE family BWK49_RS23290 a3b5df6510f2408ad56230f855785533 382 SUPERFAMILY SSF140459 2 173 4.45E-56 T 06-07-2017 BWK49_RS16875 a3848e938dbd44ccab393f63d14f0de2 400 Gene3D G3DSA:1.10.260.40 12 85 5.3E-5 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 BWK49_RS13800 4b7ffc136810987b5487367f906d82f9 522 Pfam PF03239 Iron permease FTR1 family 10 267 3.1E-39 T 06-07-2017 IPR004923 Iron permease FTR1/Fip1/EfeU GO:0005381|GO:0006827|GO:0016020|GO:0033573 BWK49_RS28285 84402800f24913b45b7b208e4c4163db 659 Gene3D G3DSA:3.40.50.1820 438 606 5.3E-4 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS28285 84402800f24913b45b7b208e4c4163db 659 Pfam PF06259 Alpha/beta hydrolase 338 518 2.5E-27 T 06-07-2017 IPR010427 Protein of unknown function DUF1023 BWK49_RS23045 8b1bc4fc7b807831ffc3a482dbaf5e71 490 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 359 442 1.8E-11 T 06-07-2017 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain BWK49_RS23045 8b1bc4fc7b807831ffc3a482dbaf5e71 490 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 88 257 1.2E-31 T 06-07-2017 IPR004474 Cell envelope-related transcriptional attenuator domain BWK49_RS23045 8b1bc4fc7b807831ffc3a482dbaf5e71 490 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 88 257 6.0E-40 T 06-07-2017 IPR004474 Cell envelope-related transcriptional attenuator domain BWK49_RS08135 e1bb4b6844a2e99396d71fb515485d61 382 Pfam PF13460 NAD(P)H-binding 7 117 2.3E-18 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS08135 e1bb4b6844a2e99396d71fb515485d61 382 Gene3D G3DSA:3.40.50.720 1 223 2.7E-36 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS08135 e1bb4b6844a2e99396d71fb515485d61 382 SUPERFAMILY SSF51735 1 282 1.3E-42 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS19470 1da6e962c46d12b4372a871a85df1569 353 Pfam PF13830 Domain of unknown function (DUF4192) 14 322 4.0E-85 T 06-07-2017 IPR025447 Protein of unknown function DUF4192 BWK49_RS11405 2ccafc1b09fa858c3e9c44d9d055e683 172 ProDom PD033474 ANTIGEN PRECURSOR SIGNAL LIPOPROTEIN LOW WEIGHT MOLECULAR LPPK MEMBRANE PALMITATE 59 172 1.0E-57 T 06-07-2017 IPR020235 Low molecular weight antigen MTB12 BWK49_RS15275 a410516836d0af2c7116d658e7f5007a 405 Pfam PF00823 PPE family 7 163 1.6E-58 T 06-07-2017 IPR000030 PPE family BWK49_RS15275 a410516836d0af2c7116d658e7f5007a 405 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 320 401 1.4E-17 T 06-07-2017 IPR022171 PPE family, C-terminal BWK49_RS15275 a410516836d0af2c7116d658e7f5007a 405 SUPERFAMILY SSF140459 4 176 3.92E-59 T 06-07-2017 BWK49_RS21745 4e12192b38e9419160bee54f2093f4d1 276 Gene3D G3DSA:3.60.130.10 5 275 1.0E-69 T 06-07-2017 BWK49_RS21745 4e12192b38e9419160bee54f2093f4d1 276 SUPERFAMILY SSF51197 7 275 1.47E-69 T 06-07-2017 BWK49_RS21745 4e12192b38e9419160bee54f2093f4d1 276 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 12 267 2.1E-59 T 06-07-2017 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 BWK49_RS26800 da3ce9f2605fcba1a27675dfff3ddf22 482 PIRSF PIRSF006446 1 478 2.1E-127 T 06-07-2017 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0016020 BWK49_RS26800 da3ce9f2605fcba1a27675dfff3ddf22 482 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 6 457 4.8E-156 T 06-07-2017 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0016020 BWK49_RS00420 f8d6ba1dd04577f825923db580f93d52 143 Pfam PF05423 Mycobacterium membrane protein 5 142 6.0E-41 T 06-07-2017 IPR008693 Transport accessory protein MmpS BWK49_RS04405 72db224d450c1e6e177505ca238119b0 100 SUPERFAMILY SSF140453 3 96 2.75E-9 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like BWK49_RS04405 72db224d450c1e6e177505ca238119b0 100 Gene3D G3DSA:1.10.287.1060 3 92 1.4E-5 T 06-07-2017 BWK49_RS11515 d8d0dec5aa1587d1ecadc2e1681f9928 659 Pfam PF04536 Acid phosphatase of thylakoid lumen protein 41 158 7.6E-17 T 06-07-2017 IPR007621 TPM domain BWK49_RS05330 a10705590000bbcd4bacf24e62c654d1 124 Pfam PF10118 Predicted metal-dependent hydrolase 25 92 1.9E-16 T 06-07-2017 IPR016516 Uncharacterised conserved protein UCP07580 BWK49_RS00800 313e88f7bf40dd1fac42c53683000325 140 SUPERFAMILY SSF54427 3 108 3.03E-21 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS00800 313e88f7bf40dd1fac42c53683000325 140 Gene3D G3DSA:3.10.450.50 5 108 1.3E-10 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS15755 b38a475c3176dbce13651b463c735f17 394 SUPERFAMILY SSF47203 227 364 9.34E-18 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 BWK49_RS15755 b38a475c3176dbce13651b463c735f17 394 Gene3D G3DSA:1.10.540.10 3 106 1.1E-31 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 BWK49_RS15755 b38a475c3176dbce13651b463c735f17 394 SUPERFAMILY SSF56645 5 204 9.56E-28 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 BWK49_RS15755 b38a475c3176dbce13651b463c735f17 394 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 237 368 4.5E-43 T 06-07-2017 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain BWK49_RS15755 b38a475c3176dbce13651b463c735f17 394 PIRSF PIRSF016578 1 390 8.4E-140 T 06-07-2017 BWK49_RS15755 b38a475c3176dbce13651b463c735f17 394 Gene3D G3DSA:1.20.140.10 202 388 1.3E-56 T 06-07-2017 BWK49_RS15755 b38a475c3176dbce13651b463c735f17 394 Gene3D G3DSA:2.40.110.10 109 201 8.4E-29 T 06-07-2017 BWK49_RS00970 4bc9a97fbe8afa67193ba918dbdaa740 161 Gene3D G3DSA:3.50.30.40 7 158 4.9E-49 T 06-07-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein BWK49_RS00970 4bc9a97fbe8afa67193ba918dbdaa740 161 SUPERFAMILY SSF89562 7 159 1.57E-46 T 06-07-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein BWK49_RS00970 4bc9a97fbe8afa67193ba918dbdaa740 161 TIGRFAM TIGR01935 NOT-MenG: RraA family 8 156 3.7E-63 T 06-07-2017 IPR010203 Regulator of ribonuclease activity A GO:0008428|GO:0051252 BWK49_RS00970 4bc9a97fbe8afa67193ba918dbdaa740 161 Pfam PF03737 Demethylmenaquinone methyltransferase 8 156 1.3E-42 T 06-07-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein BWK49_RS09840 8532f2a645c95293e026af3fa8199a3a 338 SUPERFAMILY SSF51905 1 294 4.4E-12 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS09840 8532f2a645c95293e026af3fa8199a3a 338 Gene3D G3DSA:3.50.50.60 1 191 7.0E-9 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS19410 1596bc50f039f396d72f2ee4075e3070 216 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 90 179 2.8E-13 T 06-07-2017 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain BWK49_RS07665 1c1ee65f172c06c018fa269cd095dc7c 343 Pfam PF01734 Patatin-like phospholipase 3 160 1.1E-16 T 06-07-2017 IPR002641 Patatin/Phospholipase A2-related GO:0006629 BWK49_RS07665 1c1ee65f172c06c018fa269cd095dc7c 343 Gene3D G3DSA:3.40.1090.10 3 158 3.8E-5 T 06-07-2017 BWK49_RS07665 1c1ee65f172c06c018fa269cd095dc7c 343 SUPERFAMILY SSF52151 1 175 3.4E-44 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 BWK49_RS15580 cbedce295a0c0a08f2dc99df78afa085 224 SUPERFAMILY SSF53335 39 207 6.44E-40 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS15580 cbedce295a0c0a08f2dc99df78afa085 224 Pfam PF08241 Methyltransferase domain 60 156 7.6E-23 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 BWK49_RS15580 cbedce295a0c0a08f2dc99df78afa085 224 Gene3D G3DSA:3.40.50.150 50 205 2.9E-36 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS05060 3ebce1c85945f0d8f04d0b55905d1681 214 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 65 5.1E-15 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS05060 3ebce1c85945f0d8f04d0b55905d1681 214 SUPERFAMILY SSF46689 13 90 8.98E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS05060 3ebce1c85945f0d8f04d0b55905d1681 214 Gene3D G3DSA:1.10.357.10 13 195 2.9E-28 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS05060 3ebce1c85945f0d8f04d0b55905d1681 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 3.3E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS05060 3ebce1c85945f0d8f04d0b55905d1681 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 3.3E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS19755 c96f0d2d584cb9a602d5a9db4ef5ea71 360 Gene3D G3DSA:3.40.50.720 4 200 1.1E-26 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS19755 c96f0d2d584cb9a602d5a9db4ef5ea71 360 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 7 75 4.5E-7 T 06-07-2017 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 BWK49_RS19755 c96f0d2d584cb9a602d5a9db4ef5ea71 360 SUPERFAMILY SSF51735 5 145 5.02E-15 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS19995 961e3e875b9eb2baa848c85446bdbf0c 379 TIGRFAM TIGR00802 nico: transition metal uptake transporter, Ni2+-Co2+ transporter (NiCoT) family 67 352 2.4E-124 T 06-07-2017 IPR004688 Transition metal uptake transporter nickel/cobalt GO:0015099|GO:0016021|GO:0035444|GO:0046872 BWK49_RS19995 961e3e875b9eb2baa848c85446bdbf0c 379 Pfam PF03824 High-affinity nickel-transport protein 65 357 3.1E-92 T 06-07-2017 IPR011541 Nickel/cobalt transporter, high-affinity GO:0015099|GO:0016021|GO:0035444|GO:0046872 BWK49_RS26615 f4beb082db17e28aa0665bd3a2292684 468 Gene3D G3DSA:1.20.1250.20 44 207 1.3E-9 T 06-07-2017 BWK49_RS26615 f4beb082db17e28aa0665bd3a2292684 468 Gene3D G3DSA:1.20.1250.20 238 449 9.5E-9 T 06-07-2017 BWK49_RS26615 f4beb082db17e28aa0665bd3a2292684 468 SUPERFAMILY SSF103473 12 449 1.44E-28 T 06-07-2017 IPR020846 Major facilitator superfamily domain BWK49_RS26615 f4beb082db17e28aa0665bd3a2292684 468 Pfam PF07690 Major Facilitator Superfamily 43 379 4.8E-18 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 BWK49_RS16485 1ee2341eebb75d797264f2b0bb570834 452 TIGRFAM TIGR00797 matE: MATE efflux family protein 13 426 3.1E-51 T 06-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 BWK49_RS16485 1ee2341eebb75d797264f2b0bb570834 452 Pfam PF01554 MatE 250 409 6.7E-20 T 06-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 BWK49_RS16485 1ee2341eebb75d797264f2b0bb570834 452 Pfam PF01554 MatE 13 183 6.1E-9 T 06-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 BWK49_RS28755 092433e31efaa07e5342f224eda3e967 205 Gene3D G3DSA:2.40.10.10 101 175 1.4E-9 T 06-07-2017 BWK49_RS28755 092433e31efaa07e5342f224eda3e967 205 SUPERFAMILY SSF50494 14 181 1.41E-18 T 06-07-2017 IPR009003 Peptidase S1, PA clan BWK49_RS28755 092433e31efaa07e5342f224eda3e967 205 Gene3D G3DSA:2.40.10.10 15 90 1.6E-9 T 06-07-2017 BWK49_RS02885 05fec26a758e9b6c79fb46a0c1dfd69a 387 SUPERFAMILY SSF52540 39 344 7.08E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS02885 05fec26a758e9b6c79fb46a0c1dfd69a 387 TIGRFAM TIGR03819 heli_sec_ATPase: helicase/secretion neighborhood ATPase 5 350 2.8E-155 T 06-07-2017 IPR022399 Helicase/secretion neighbourhood ATPase BWK49_RS02885 05fec26a758e9b6c79fb46a0c1dfd69a 387 Gene3D G3DSA:3.30.450.90 55 155 4.1E-17 T 06-07-2017 BWK49_RS02885 05fec26a758e9b6c79fb46a0c1dfd69a 387 Gene3D G3DSA:3.40.50.300 167 355 4.0E-45 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS02885 05fec26a758e9b6c79fb46a0c1dfd69a 387 Pfam PF00437 Type II/IV secretion system protein 57 338 1.9E-69 T 06-07-2017 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 BWK49_RS26520 9bb2bd138aaf800c8fbf68ea3f1ea13c 451 SUPERFAMILY SSF52777 62 145 1.22E-5 T 06-07-2017 BWK49_RS05145 48f7eed9150afbd1a04399be2bfd50ab 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 7.7E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS05145 48f7eed9150afbd1a04399be2bfd50ab 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 7.7E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS05145 48f7eed9150afbd1a04399be2bfd50ab 214 Gene3D G3DSA:1.10.357.10 16 196 5.1E-30 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS05145 48f7eed9150afbd1a04399be2bfd50ab 214 SUPERFAMILY SSF46689 13 88 6.98E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS05145 48f7eed9150afbd1a04399be2bfd50ab 214 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 66 1.3E-15 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS27245 6417df82e9d0bd71d96d6d1ae1ab7408 383 Pfam PF02470 MlaD protein 46 117 2.2E-10 T 06-07-2017 IPR003399 Mce/MlaD BWK49_RS27245 6417df82e9d0bd71d96d6d1ae1ab7408 383 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 13 302 1.4E-83 T 06-07-2017 IPR005693 Virulence factor Mce protein BWK49_RS13670 d144432e342b53ebc787b8e2e833ee2f 367 SUPERFAMILY SSF51735 9 159 1.46E-12 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS13670 d144432e342b53ebc787b8e2e833ee2f 367 Gene3D G3DSA:3.40.50.720 7 171 2.6E-21 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS20270 26b8a1baa26eb44c94558b53bae244f9 239 Gene3D G3DSA:3.30.420.10 32 173 6.8E-38 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS20270 26b8a1baa26eb44c94558b53bae244f9 239 Pfam PF01351 Ribonuclease HII 33 212 7.1E-44 T 06-07-2017 IPR024567 Ribonuclease HII/HIII domain BWK49_RS20270 26b8a1baa26eb44c94558b53bae244f9 239 SUPERFAMILY SSF53098 21 218 1.67E-61 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS20270 26b8a1baa26eb44c94558b53bae244f9 239 Hamap MF_00052_B Ribonuclease HII [rnhB]. 31 212 37.289 T 06-07-2017 IPR022898 Ribonuclease HII GO:0004523 BWK49_RS17040 be0bbc2c449aea9e22d51008dc35d789 708 Gene3D G3DSA:3.40.50.720 87 229 1.2E-20 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS17040 be0bbc2c449aea9e22d51008dc35d789 708 Gene3D G3DSA:3.40.109.30 367 432 3.0E-5 T 06-07-2017 BWK49_RS17040 be0bbc2c449aea9e22d51008dc35d789 708 Pfam PF00899 ThiF family 90 237 2.1E-22 T 06-07-2017 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 BWK49_RS17040 be0bbc2c449aea9e22d51008dc35d789 708 Gene3D G3DSA:3.40.109.10 593 700 2.5E-4 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 BWK49_RS17040 be0bbc2c449aea9e22d51008dc35d789 708 Gene3D G3DSA:3.40.109.10 476 477 2.5E-4 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 BWK49_RS17040 be0bbc2c449aea9e22d51008dc35d789 708 SUPERFAMILY SSF69572 84 249 2.49E-28 T 06-07-2017 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 BWK49_RS18335 3b7b51cdb804ad6ac67a85daac6cfe38 112 PIRSF PIRSF010611 1 112 2.6E-50 T 06-07-2017 IPR016572 Uncharacterised conserved protein UCP010611 BWK49_RS18335 3b7b51cdb804ad6ac67a85daac6cfe38 112 TIGRFAM TIGR04529 MTB_hemophore: hemophore-related protein, Rv0203/Rv1174c family 41 109 5.0E-14 T 06-07-2017 IPR032407 Haemophore, haem-binding GO:0020037 BWK49_RS00750 1e4e539a6054ff16abc572de4d29cb1c 190 Gene3D G3DSA:1.20.120.520 6 124 6.7E-9 T 06-07-2017 BWK49_RS00750 1e4e539a6054ff16abc572de4d29cb1c 190 Pfam PF01814 Hemerythrin HHE cation binding domain 7 122 6.4E-11 T 06-07-2017 IPR012312 Haemerythrin-like Reactome: R-HSA-390471 BWK49_RS00020 d9a7a7fefe55c05f6252c18a9f97abdd 187 Hamap MF_00630 UPF0232 protein . 1 174 36.069 T 06-07-2017 IPR023007 Uncharacterised protein family UPF0232, actinobacteria BWK49_RS00020 d9a7a7fefe55c05f6252c18a9f97abdd 187 Pfam PF05258 Protein of unknown function (DUF721) 75 162 2.1E-23 T 06-07-2017 IPR007922 Protein of unknown function DUF721/UPF0232 BWK49_RS01205 724793f54d3b433d392a7a4f2ff21a44 1064 Pfam PF14896 EmbC C-terminal domain 683 1061 2.5E-138 T 06-07-2017 IPR032731 Arabinosyltransferase, C-terminal BWK49_RS01205 724793f54d3b433d392a7a4f2ff21a44 1064 Gene3D G3DSA:2.60.120.610 27 203 8.1E-68 T 06-07-2017 IPR027451 Arabinofuranosyltransferase, domain 1 BWK49_RS01205 724793f54d3b433d392a7a4f2ff21a44 1064 Pfam PF04602 Mycobacterial cell wall arabinan synthesis protein 6 652 2.9E-289 T 06-07-2017 IPR007680 Arabinofuranosyltransferase, N-terminal GO:0052636|GO:0071766 BWK49_RS12170 0d87ddca67fc9511f7622485402dd295 508 SUPERFAMILY SSF51905 280 373 1.2E-51 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS12170 0d87ddca67fc9511f7622485402dd295 508 SUPERFAMILY SSF51905 6 172 1.2E-51 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS12170 0d87ddca67fc9511f7622485402dd295 508 Pfam PF01494 FAD binding domain 6 358 1.4E-61 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 BWK49_RS12170 0d87ddca67fc9511f7622485402dd295 508 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 308 324 5.5E-39 T 06-07-2017 BWK49_RS12170 0d87ddca67fc9511f7622485402dd295 508 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 344 360 5.5E-39 T 06-07-2017 BWK49_RS12170 0d87ddca67fc9511f7622485402dd295 508 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 151 166 5.5E-39 T 06-07-2017 BWK49_RS12170 0d87ddca67fc9511f7622485402dd295 508 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 326 344 5.5E-39 T 06-07-2017 BWK49_RS12170 0d87ddca67fc9511f7622485402dd295 508 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 5.5E-39 T 06-07-2017 BWK49_RS12170 0d87ddca67fc9511f7622485402dd295 508 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 293 308 5.5E-39 T 06-07-2017 BWK49_RS12170 0d87ddca67fc9511f7622485402dd295 508 Gene3D G3DSA:3.50.50.60 6 177 9.2E-46 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS12170 0d87ddca67fc9511f7622485402dd295 508 Gene3D G3DSA:3.50.50.60 281 360 9.2E-46 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS26425 cd4c20ec85f534339acdbdf6226fc8ab 307 Pfam PF14011 EspG family 11 270 6.8E-62 T 06-07-2017 IPR025734 EspG family BWK49_RS28160 1583e2668eafbbe0b8bf9871f4745e0e 364 Pfam PF06742 Protein of unknown function (DUF1214) 96 176 0.022 T 06-07-2017 IPR010621 Domain of unknown function DUF1214 BWK49_RS28160 1583e2668eafbbe0b8bf9871f4745e0e 364 Pfam PF06742 Protein of unknown function (DUF1214) 273 347 7.4E-5 T 06-07-2017 IPR010621 Domain of unknown function DUF1214 BWK49_RS07105 1ebb015070d8a60b9f696ad1ea7e2bd3 226 SMART SM00858 54 116 2.4E-6 T 06-07-2017 IPR013974 SAF domain Reactome: R-HSA-4085001 BWK49_RS07105 1ebb015070d8a60b9f696ad1ea7e2bd3 226 Pfam PF08666 SAF domain 55 111 2.4E-7 T 06-07-2017 IPR013974 SAF domain Reactome: R-HSA-4085001 BWK49_RS02850 10cf5fbb4071ec276a693db78ae5ae77 266 SUPERFAMILY SSF161098 57 245 2.62E-25 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS02850 10cf5fbb4071ec276a693db78ae5ae77 266 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 78 261 3.0E-30 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS02850 10cf5fbb4071ec276a693db78ae5ae77 266 Gene3D G3DSA:1.10.3720.10 54 259 2.1E-25 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 BWK49_RS11320 41326f14435c9f0af94e063121a6269f 463 SUPERFAMILY SSF52777 36 230 1.22E-16 T 06-07-2017 BWK49_RS11320 41326f14435c9f0af94e063121a6269f 463 Pfam PF00668 Condensation domain 68 330 5.7E-10 T 06-07-2017 IPR001242 Condensation domain BWK49_RS11320 41326f14435c9f0af94e063121a6269f 463 SUPERFAMILY SSF52777 225 456 1.56E-15 T 06-07-2017 BWK49_RS10975 c9f6235bc386b2b2249e73b4e4ffc9c3 148 Gene3D G3DSA:3.10.450.50 2 144 1.0E-18 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS10975 c9f6235bc386b2b2249e73b4e4ffc9c3 148 SUPERFAMILY SSF54427 1 145 1.72E-24 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS10975 c9f6235bc386b2b2249e73b4e4ffc9c3 148 Pfam PF13577 SnoaL-like domain 5 135 9.6E-15 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain BWK49_RS22815 e9e5ff9c6c6b3d2339737496f965987d 207 SUPERFAMILY SSF46689 6 88 1.85E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS22815 e9e5ff9c6c6b3d2339737496f965987d 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 63 4.9E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS22815 e9e5ff9c6c6b3d2339737496f965987d 207 Gene3D G3DSA:1.10.357.10 14 197 5.5E-23 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS11570 fb92e7796e1adde133fd7b3291b3bedb 376 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 273 372 1.0E-8 T 06-07-2017 BWK49_RS11570 fb92e7796e1adde133fd7b3291b3bedb 376 Pfam PF03601 Conserved hypothetical protein 698 31 348 8.2E-97 T 06-07-2017 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 BWK49_RS10740 1c0ab65ddba97c151d7e4c6e047e1c4d 96 Pfam PF02583 Metal-sensitive transcriptional repressor 14 91 7.9E-29 T 06-07-2017 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 BWK49_RS22250 27637e1df8a3e33d3ae1ea7f46500baf 338 Pfam PF14032 PknH-like extracellular domain 140 335 9.8E-31 T 06-07-2017 IPR026954 PknH-like extracellular domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 BWK49_RS22250 27637e1df8a3e33d3ae1ea7f46500baf 338 Pfam PF13828 Domain of unknown function (DUF4190) 56 109 9.4E-11 T 06-07-2017 IPR025241 Domain of unknown function DUF4190 BWK49_RS11655 050ab4ae08e6baee094d24f60eacf2a6 288 Gene3D G3DSA:1.20.1290.10 142 267 4.1E-21 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 BWK49_RS11655 050ab4ae08e6baee094d24f60eacf2a6 288 SUPERFAMILY SSF69118 148 265 1.58E-19 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 BWK49_RS04930 444814a67ff60a6e367e97ed8433072b 521 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 90 106 3.8E-86 T 06-07-2017 IPR005693 Virulence factor Mce protein BWK49_RS04930 444814a67ff60a6e367e97ed8433072b 521 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 28 48 3.8E-86 T 06-07-2017 IPR005693 Virulence factor Mce protein BWK49_RS04930 444814a67ff60a6e367e97ed8433072b 521 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 177 195 3.8E-86 T 06-07-2017 IPR005693 Virulence factor Mce protein BWK49_RS04930 444814a67ff60a6e367e97ed8433072b 521 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 346 364 3.8E-86 T 06-07-2017 IPR005693 Virulence factor Mce protein BWK49_RS04930 444814a67ff60a6e367e97ed8433072b 521 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 246 265 3.8E-86 T 06-07-2017 IPR005693 Virulence factor Mce protein BWK49_RS04930 444814a67ff60a6e367e97ed8433072b 521 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 296 315 3.8E-86 T 06-07-2017 IPR005693 Virulence factor Mce protein BWK49_RS04930 444814a67ff60a6e367e97ed8433072b 521 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 128 152 3.8E-86 T 06-07-2017 IPR005693 Virulence factor Mce protein BWK49_RS04930 444814a67ff60a6e367e97ed8433072b 521 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 325 342 3.8E-86 T 06-07-2017 IPR005693 Virulence factor Mce protein BWK49_RS04930 444814a67ff60a6e367e97ed8433072b 521 Pfam PF02470 MlaD protein 41 112 6.7E-13 T 06-07-2017 IPR003399 Mce/MlaD BWK49_RS04930 444814a67ff60a6e367e97ed8433072b 521 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 12 283 1.1E-73 T 06-07-2017 IPR005693 Virulence factor Mce protein BWK49_RS04930 444814a67ff60a6e367e97ed8433072b 521 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 157 281 5.8E-7 T 06-07-2017 IPR024516 Mammalian cell entry, C-terminal BWK49_RS21325 44533adc4f148351c79d10d3e33e2e29 242 Gene3D G3DSA:1.10.357.10 19 214 1.2E-30 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS21325 44533adc4f148351c79d10d3e33e2e29 242 SUPERFAMILY SSF46689 23 95 1.44E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS21325 44533adc4f148351c79d10d3e33e2e29 242 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 55 78 6.7E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS21325 44533adc4f148351c79d10d3e33e2e29 242 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 48 6.7E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS21325 44533adc4f148351c79d10d3e33e2e29 242 SUPERFAMILY SSF48498 102 201 4.0E-8 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS21325 44533adc4f148351c79d10d3e33e2e29 242 Pfam PF00440 Bacterial regulatory proteins, tetR family 35 80 4.3E-12 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS15425 54dbd4ace26790df26f9bacd47214c1f 123 Gene3D G3DSA:1.10.472.20 43 122 1.3E-11 T 06-07-2017 BWK49_RS15425 54dbd4ace26790df26f9bacd47214c1f 123 SUPERFAMILY SSF50090 41 121 1.1E-7 T 06-07-2017 IPR008990 Electron transport accessory protein-like domain BWK49_RS22625 e6531e73e2e14fd206c9b9322114903e 706 SMART SM00341 633 706 3.5E-16 T 06-07-2017 IPR002121 HRDC domain GO:0003676|GO:0005622 BWK49_RS22625 e6531e73e2e14fd206c9b9322114903e 706 Pfam PF00580 UvrD/REP helicase N-terminal domain 15 289 6.4E-45 T 06-07-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 BWK49_RS22625 e6531e73e2e14fd206c9b9322114903e 706 Gene3D G3DSA:3.40.50.300 14 294 1.2E-64 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS22625 e6531e73e2e14fd206c9b9322114903e 706 Gene3D G3DSA:1.10.150.80 636 702 1.6E-14 T 06-07-2017 IPR002121 HRDC domain GO:0003676|GO:0005622 BWK49_RS22625 e6531e73e2e14fd206c9b9322114903e 706 Pfam PF00570 HRDC domain 637 703 1.6E-21 T 06-07-2017 IPR002121 HRDC domain GO:0003676|GO:0005622 BWK49_RS22625 e6531e73e2e14fd206c9b9322114903e 706 Gene3D G3DSA:3.40.50.300 501 589 1.4E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS22625 e6531e73e2e14fd206c9b9322114903e 706 Gene3D G3DSA:3.40.50.300 299 413 1.4E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS22625 e6531e73e2e14fd206c9b9322114903e 706 Pfam PF13361 UvrD-like helicase C-terminal domain 296 417 7.7E-16 T 06-07-2017 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 BWK49_RS22625 e6531e73e2e14fd206c9b9322114903e 706 Pfam PF13361 UvrD-like helicase C-terminal domain 461 567 4.9E-20 T 06-07-2017 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 BWK49_RS22625 e6531e73e2e14fd206c9b9322114903e 706 SUPERFAMILY SSF52540 4 589 3.36E-125 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS22625 e6531e73e2e14fd206c9b9322114903e 706 SUPERFAMILY SSF47819 627 705 5.67E-21 T 06-07-2017 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 BWK49_RS08835 68f2109534f2cf1fc3918af7ae41699b 288 Pfam PF13374 Tetratricopeptide repeat 145 173 3.7E-4 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 BWK49_RS17415 85038db6a36eb56891090a276c0627fe 169 Pfam PF04191 Phospholipid methyltransferase 46 147 9.0E-17 T 06-07-2017 IPR007318 Phospholipid methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825|Reactome: R-HSA-1483191 BWK49_RS03765 d8feb16dde4188dc947669246c5be77c 134 PRINTS PR00332 Histidine triad family signature 4 20 3.6E-14 T 06-07-2017 IPR001310 Histidine triad (HIT) protein BWK49_RS03765 d8feb16dde4188dc947669246c5be77c 134 PRINTS PR00332 Histidine triad family signature 25 43 3.6E-14 T 06-07-2017 IPR001310 Histidine triad (HIT) protein BWK49_RS03765 d8feb16dde4188dc947669246c5be77c 134 PRINTS PR00332 Histidine triad family signature 87 97 3.6E-14 T 06-07-2017 IPR001310 Histidine triad (HIT) protein BWK49_RS03765 d8feb16dde4188dc947669246c5be77c 134 SUPERFAMILY SSF54197 3 132 1.18E-32 T 06-07-2017 IPR011146 HIT-like domain GO:0003824 BWK49_RS03765 d8feb16dde4188dc947669246c5be77c 134 Gene3D G3DSA:3.30.428.10 4 131 1.9E-26 T 06-07-2017 IPR011146 HIT-like domain GO:0003824 BWK49_RS03765 d8feb16dde4188dc947669246c5be77c 134 Pfam PF01230 HIT domain 11 101 5.3E-23 T 06-07-2017 IPR001310 Histidine triad (HIT) protein BWK49_RS23035 062634b0080c164a6a3d11289b8bbe88 296 SUPERFAMILY SSF53448 7 259 3.84E-46 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases BWK49_RS23035 062634b0080c164a6a3d11289b8bbe88 296 Gene3D G3DSA:3.90.550.10 7 254 2.3E-41 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases BWK49_RS23035 062634b0080c164a6a3d11289b8bbe88 296 Pfam PF00535 Glycosyl transferase family 2 7 189 5.2E-19 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 BWK49_RS23540 edc96dc75b8563438d566c1b5dbedaef 172 Pfam PF05305 Protein of unknown function (DUF732) 13 104 7.5E-22 T 06-07-2017 IPR007969 Domain of unknown function DUF732 BWK49_RS28280 229faaf19446670be86330a51e227c35 109 ProDom PD069409 MB2104 RV2078/MT2139 1 98 3.0E-38 T 06-07-2017 IPR022534 Protein of unknown function DUF2563 BWK49_RS28280 229faaf19446670be86330a51e227c35 109 Pfam PF10817 Protein of unknown function (DUF2563) 1 103 8.6E-52 T 06-07-2017 IPR022534 Protein of unknown function DUF2563 BWK49_RS09700 5e8d85e78ed0237e6c53d543b939a942 521 Pfam PF05872 Bacterial protein of unknown function (DUF853) 35 520 8.8E-178 T 06-07-2017 IPR033186 Helicase HerA-like C-terminal BWK49_RS09700 5e8d85e78ed0237e6c53d543b939a942 521 SUPERFAMILY SSF52540 13 395 3.81E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS09700 5e8d85e78ed0237e6c53d543b939a942 521 Gene3D G3DSA:3.40.50.300 40 113 2.2E-51 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS09700 5e8d85e78ed0237e6c53d543b939a942 521 Gene3D G3DSA:3.40.50.300 231 395 2.2E-51 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS14760 4dbb588fc7c1ed6e23cdbd4e379e83fe 140 Pfam PF05481 Mycobacterium 19 kDa lipoprotein antigen 24 140 1.1E-11 T 06-07-2017 IPR008691 19kDa lipoprotein antigen GO:0016020 BWK49_RS16685 09dc3b756238efdbe8e1f041e4709e77 108 Pfam PF05305 Protein of unknown function (DUF732) 6 97 1.1E-21 T 06-07-2017 IPR007969 Domain of unknown function DUF732 BWK49_RS10575 6ae94ee12ad78de49dd679aa56c925e1 100 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 6 93 9.9E-9 T 06-07-2017 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 BWK49_RS10575 6ae94ee12ad78de49dd679aa56c925e1 100 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 1 100 12.654 T 06-07-2017 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 BWK49_RS15060 83a4233d8e28567bff52baf22613f829 327 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 43 281 1.6E-27 T 06-07-2017 IPR018713 Domain of unknown function DUF2236 BWK49_RS04690 6b51a03ca210490a1b9fb65dac7cc060 485 PRINTS PR00385 P450 superfamily signature 424 433 1.7E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS04690 6b51a03ca210490a1b9fb65dac7cc060 485 PRINTS PR00385 P450 superfamily signature 433 444 1.7E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS04690 6b51a03ca210490a1b9fb65dac7cc060 485 PRINTS PR00385 P450 superfamily signature 297 314 1.7E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS04690 6b51a03ca210490a1b9fb65dac7cc060 485 PRINTS PR00385 P450 superfamily signature 348 359 1.7E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS04690 6b51a03ca210490a1b9fb65dac7cc060 485 Pfam PF00067 Cytochrome P450 61 459 1.0E-66 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS04690 6b51a03ca210490a1b9fb65dac7cc060 485 Gene3D G3DSA:1.10.630.10 54 485 1.3E-97 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS04690 6b51a03ca210490a1b9fb65dac7cc060 485 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 426 435 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 BWK49_RS04690 6b51a03ca210490a1b9fb65dac7cc060 485 SUPERFAMILY SSF48264 53 485 6.55E-95 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS04690 6b51a03ca210490a1b9fb65dac7cc060 485 PRINTS PR00465 E-class P450 group IV signature 55 72 4.7E-20 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS04690 6b51a03ca210490a1b9fb65dac7cc060 485 PRINTS PR00465 E-class P450 group IV signature 433 451 4.7E-20 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS04690 6b51a03ca210490a1b9fb65dac7cc060 485 PRINTS PR00465 E-class P450 group IV signature 376 390 4.7E-20 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS04690 6b51a03ca210490a1b9fb65dac7cc060 485 PRINTS PR00465 E-class P450 group IV signature 392 410 4.7E-20 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS04690 6b51a03ca210490a1b9fb65dac7cc060 485 PRINTS PR00465 E-class P450 group IV signature 343 359 4.7E-20 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS04690 6b51a03ca210490a1b9fb65dac7cc060 485 PRINTS PR00465 E-class P450 group IV signature 417 433 4.7E-20 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS04690 6b51a03ca210490a1b9fb65dac7cc060 485 PRINTS PR00465 E-class P450 group IV signature 288 314 4.7E-20 T 06-07-2017 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 BWK49_RS13960 726ba808586ac830ef9dd463af504b63 312 Pfam PF06527 TniQ 15 134 2.2E-9 T 06-07-2017 IPR009492 TniQ BWK49_RS19360 1b09a3987c51808c73e0cddeccfe8d9a 664 Pfam PF13520 Amino acid permease 56 459 1.4E-24 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 BWK49_RS27380 78f089d887b9cca18a5553057111ff2a 158 SUPERFAMILY SSF55961 8 153 1.16E-12 T 06-07-2017 BWK49_RS27380 78f089d887b9cca18a5553057111ff2a 158 Gene3D G3DSA:3.30.530.20 7 121 1.3E-4 T 06-07-2017 IPR023393 START-like domain BWK49_RS02740 d7b76df5e752605e388dc749fc2c5ded 319 Gene3D G3DSA:3.60.21.10 50 246 2.2E-13 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like BWK49_RS02740 d7b76df5e752605e388dc749fc2c5ded 319 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 52 233 3.8E-9 T 06-07-2017 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 BWK49_RS02740 d7b76df5e752605e388dc749fc2c5ded 319 SUPERFAMILY SSF56300 47 289 7.25E-28 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like BWK49_RS12970 ad01e82aa8943f7d117f05133b0441c9 409 Pfam PF09594 Protein of unknown function (DUF2029) 62 306 1.6E-60 T 06-07-2017 IPR018584 Glycosyltransferase family 87 GO:0016758 BWK49_RS20255 dfabd857f7f9b266cb29315f08c8d1d4 329 SUPERFAMILY SSF51735 1 325 6.57E-54 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS20255 dfabd857f7f9b266cb29315f08c8d1d4 329 Gene3D G3DSA:3.40.50.720 4 221 2.2E-38 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS20255 dfabd857f7f9b266cb29315f08c8d1d4 329 Gene3D G3DSA:3.90.25.10 222 324 1.6E-11 T 06-07-2017 BWK49_RS20255 dfabd857f7f9b266cb29315f08c8d1d4 329 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 246 5.5E-27 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 BWK49_RS04860 62136f47eb7172ced83b5a1fbc753843 235 Gene3D G3DSA:1.10.357.10 18 211 2.2E-28 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS04860 62136f47eb7172ced83b5a1fbc753843 235 SUPERFAMILY SSF48498 101 212 1.05E-9 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS04860 62136f47eb7172ced83b5a1fbc753843 235 SUPERFAMILY SSF46689 22 104 9.23E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS04860 62136f47eb7172ced83b5a1fbc753843 235 Pfam PF00440 Bacterial regulatory proteins, tetR family 35 80 8.7E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 BWK49_RS06820 01f375e56480e504c5002091c423bb4c 60 Pfam PF05901 Excalibur calcium-binding domain 24 59 1.3E-14 T 06-07-2017 IPR008613 Excalibur calcium-binding domain BWK49_RS06820 01f375e56480e504c5002091c423bb4c 60 SMART SM00894 23 59 8.8E-17 T 06-07-2017 IPR008613 Excalibur calcium-binding domain BWK49_RS06665 dbaeb90b859557ef3503f01646a5864d 256 Pfam PF11268 Protein of unknown function (DUF3071) 1 171 1.2E-56 T 06-07-2017 IPR021421 Protein of unknown function DUF3071 BWK49_RS04415 5e164ad383b8c0ff7616b4f9d19f0a8a 313 Pfam PF14011 EspG family 16 294 7.6E-34 T 06-07-2017 IPR025734 EspG family BWK49_RS22915 aed270d504039364c3fc53a91dab8eeb 210 SUPERFAMILY SSF53271 29 209 4.71E-15 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like BWK49_RS22915 aed270d504039364c3fc53a91dab8eeb 210 Gene3D G3DSA:3.40.50.2020 49 209 3.3E-16 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like BWK49_RS01015 9a079725840aa297b72c44f89ca403e9 243 Pfam PF14219 Domain of unknown function (DUF4328) 53 206 1.8E-30 T 06-07-2017 IPR025565 Domain of unknown function DUF4328 BWK49_RS15100 3fe85ccf8e4a7da9486be8f601a6648c 270 Pfam PF05949 Bacterial protein of unknown function (DUF881) 129 267 2.8E-36 T 06-07-2017 IPR010273 Protein of unknown function DUF881 BWK49_RS06645 769e6ae2674ade00f72f9a6331962d22 95 Pfam PF10745 Protein of unknown function (DUF2530) 14 88 8.5E-25 T 06-07-2017 IPR019681 Protein of unknown function DUF2530 BWK49_RS05050 d02dba085bbe4e46471f43d7434eabdb 298 Gene3D G3DSA:3.40.50.1820 6 292 1.7E-54 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS05050 d02dba085bbe4e46471f43d7434eabdb 298 SUPERFAMILY SSF53474 3 292 1.55E-43 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS05050 d02dba085bbe4e46471f43d7434eabdb 298 Pfam PF12697 Alpha/beta hydrolase family 30 284 4.1E-17 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 BWK49_RS14175 0cc75df6e4d1b7554ef9920d1b62a8da 216 Pfam PF06414 Zeta toxin 12 130 4.9E-8 T 06-07-2017 IPR010488 Zeta toxin domain GO:0005524|GO:0016301 BWK49_RS14175 0cc75df6e4d1b7554ef9920d1b62a8da 216 Gene3D G3DSA:3.40.50.300 10 143 1.5E-7 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS14175 0cc75df6e4d1b7554ef9920d1b62a8da 216 SUPERFAMILY SSF52540 9 153 2.61E-10 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS05170 6902f126ca4cb089415e96b916ef54ee 101 SUPERFAMILY SSF53098 7 100 5.69E-8 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 BWK49_RS09400 7b0566933c8a588a33afc0d9df157923 150 Gene3D G3DSA:3.10.450.50 9 136 1.2E-27 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS09400 7b0566933c8a588a33afc0d9df157923 150 Pfam PF13577 SnoaL-like domain 8 135 9.2E-25 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain BWK49_RS09400 7b0566933c8a588a33afc0d9df157923 150 SUPERFAMILY SSF54427 5 140 4.1E-32 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS22710 38c629640c6e0bc8ea3249588d83aecc 408 SUPERFAMILY SSF50998 240 367 1.15E-5 T 06-07-2017 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily BWK49_RS22710 38c629640c6e0bc8ea3249588d83aecc 408 SUPERFAMILY SSF50998 15 86 1.15E-5 T 06-07-2017 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily BWK49_RS22710 38c629640c6e0bc8ea3249588d83aecc 408 SUPERFAMILY SSF50998 129 186 1.15E-5 T 06-07-2017 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily BWK49_RS12010 a124739a530595d8fee405529075f137 247 Pfam PF14032 PknH-like extracellular domain 44 243 1.3E-39 T 06-07-2017 IPR026954 PknH-like extracellular domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 BWK49_RS22080 0623dbcb58e25ac1a062f7b1d804f13a 315 Pfam PF13559 Domain of unknown function (DUF4129) 233 303 1.5E-10 T 06-07-2017 IPR025403 Domain of unknown function DUF4129 BWK49_RS26410 59e571b019b469def46f772979082039 343 Pfam PF11203 Putative type VII ESX secretion system translocon, EccE 127 213 3.4E-14 T 06-07-2017 IPR021368 Type VII secretion system protein EccE BWK49_RS26410 59e571b019b469def46f772979082039 343 TIGRFAM TIGR03923 T7SS_EccE: type VII secretion protein EccE 9 292 1.3E-68 T 06-07-2017 IPR021368 Type VII secretion system protein EccE BWK49_RS11045 b0d7f7a1f6acfbde6c69293ba238f5c3 266 SUPERFAMILY SSF52096 1 261 1.34E-61 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS11045 b0d7f7a1f6acfbde6c69293ba238f5c3 266 Gene3D G3DSA:3.90.226.10 2 259 3.0E-61 T 06-07-2017 IPR029045 ClpP/crotonase-like domain BWK49_RS11045 b0d7f7a1f6acfbde6c69293ba238f5c3 266 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 260 9.9E-41 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 BWK49_RS28990 297c6f2e5b0e9a2586f6accd659279fe 94 Pfam PF06013 Proteins of 100 residues with WXG 3 87 7.6E-14 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like BWK49_RS28990 297c6f2e5b0e9a2586f6accd659279fe 94 SUPERFAMILY SSF140453 2 93 6.8E-17 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like BWK49_RS28990 297c6f2e5b0e9a2586f6accd659279fe 94 Gene3D G3DSA:1.10.287.1060 2 94 1.8E-13 T 06-07-2017 BWK49_RS23770 10e3eeff128467c0b177ff6d8a41b209 137 ProDom PD032647 MB3446 ML0386 RV3412/MT3521 CGL0602 25 120 5.0E-50 T 06-07-2017 BWK49_RS28190 79345c53103aa65f23ce9b8c30a8b3b2 359 Pfam PF01636 Phosphotransferase enzyme family 55 259 1.4E-26 T 06-07-2017 IPR002575 Aminoglycoside phosphotransferase BWK49_RS28190 79345c53103aa65f23ce9b8c30a8b3b2 359 SUPERFAMILY SSF56112 55 317 1.43E-44 T 06-07-2017 IPR011009 Protein kinase-like domain BWK49_RS28190 79345c53103aa65f23ce9b8c30a8b3b2 359 Gene3D G3DSA:3.90.1200.10 136 311 5.0E-29 T 06-07-2017 BWK49_RS28965 709ca83900400242c0756c87e4b905f1 513 TIGRFAM TIGR03919 T7SS_EccB: type VII secretion protein EccB 24 488 4.0E-140 T 06-07-2017 IPR007795 Type VII secretion system EccB BWK49_RS28965 709ca83900400242c0756c87e4b905f1 513 Pfam PF05108 Type VII secretion system ESX-1, transport TM domain B 22 500 5.5E-142 T 06-07-2017 IPR007795 Type VII secretion system EccB BWK49_RS26750 9ccb5b23e40edbf974e16eefc9be5ffc 482 Pfam PF06762 Lipase maturation factor 293 474 6.1E-67 T 06-07-2017 IPR009613 Lipase maturation factor Reactome: R-HSA-192456 BWK49_RS26750 9ccb5b23e40edbf974e16eefc9be5ffc 482 Pfam PF06762 Lipase maturation factor 121 273 7.4E-61 T 06-07-2017 IPR009613 Lipase maturation factor Reactome: R-HSA-192456 BWK49_RS08825 29f5f5ec87901d6a7a3af1ed9278e174 137 Gene3D G3DSA:3.10.180.10 5 135 1.2E-27 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS08825 29f5f5ec87901d6a7a3af1ed9278e174 137 SUPERFAMILY SSF54593 5 136 2.75E-27 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS08825 29f5f5ec87901d6a7a3af1ed9278e174 137 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 133 6.0E-12 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain BWK49_RS05795 a347e71e993ae50a602144d18aa682a8 347 Gene3D G3DSA:3.40.50.10540 290 343 7.8E-71 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS05795 a347e71e993ae50a602144d18aa682a8 347 Gene3D G3DSA:3.40.50.10540 5 206 7.8E-71 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS05795 a347e71e993ae50a602144d18aa682a8 347 Gene3D G3DSA:3.30.1540.10 215 289 3.0E-14 T 06-07-2017 BWK49_RS05795 a347e71e993ae50a602144d18aa682a8 347 Pfam PF02515 CoA-transferase family III 9 310 2.3E-79 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 BWK49_RS05795 a347e71e993ae50a602144d18aa682a8 347 SUPERFAMILY SSF89796 3 341 4.84E-91 T 06-07-2017 IPR023606 CoA-transferase family III domain BWK49_RS24370 c8dc1ccbdfe11199cfc950f862905fc1 107 TIGRFAM TIGR03967 mycofact_MftB: putative mycofactocin binding protein MftB 21 100 1.0E-29 T 06-07-2017 IPR023850 Putative mycofactocin binding protein MftB BWK49_RS00445 778fcbd2d7745a2782ea526df4bd2bde 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.5E-20 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS00445 778fcbd2d7745a2782ea526df4bd2bde 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 1.5E-20 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS00445 778fcbd2d7745a2782ea526df4bd2bde 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 1.5E-20 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS00445 778fcbd2d7745a2782ea526df4bd2bde 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.5E-20 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS00445 778fcbd2d7745a2782ea526df4bd2bde 261 Pfam PF00106 short chain dehydrogenase 7 196 3.0E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS00445 778fcbd2d7745a2782ea526df4bd2bde 261 SUPERFAMILY SSF51735 4 239 3.64E-55 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS00445 778fcbd2d7745a2782ea526df4bd2bde 261 Gene3D G3DSA:3.40.50.720 4 245 2.0E-55 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS10965 2ede544c9c9e53991cbfa1c4f0e09168 397 Pfam PF04909 Amidohydrolase 97 393 6.4E-25 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 BWK49_RS10965 2ede544c9c9e53991cbfa1c4f0e09168 397 Gene3D G3DSA:3.20.20.140 10 37 5.0E-58 T 06-07-2017 BWK49_RS10965 2ede544c9c9e53991cbfa1c4f0e09168 397 Gene3D G3DSA:3.20.20.140 77 394 5.0E-58 T 06-07-2017 BWK49_RS10965 2ede544c9c9e53991cbfa1c4f0e09168 397 SUPERFAMILY SSF51556 92 393 6.05E-68 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS10965 2ede544c9c9e53991cbfa1c4f0e09168 397 SUPERFAMILY SSF51556 7 37 6.05E-68 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS25645 a57b55ff5dd67fce2a4ff262242d9be7 316 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 22 169 0.0061 T 06-07-2017 BWK49_RS25645 a57b55ff5dd67fce2a4ff262242d9be7 316 Pfam PF00106 short chain dehydrogenase 23 231 1.8E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS25645 a57b55ff5dd67fce2a4ff262242d9be7 316 Gene3D G3DSA:3.40.50.720 20 276 1.6E-55 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS25645 a57b55ff5dd67fce2a4ff262242d9be7 316 SUPERFAMILY SSF51735 17 312 1.65E-50 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS25645 a57b55ff5dd67fce2a4ff262242d9be7 316 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 103 114 5.8E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS25645 a57b55ff5dd67fce2a4ff262242d9be7 316 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 23 40 5.8E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS25645 a57b55ff5dd67fce2a4ff262242d9be7 316 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 164 5.8E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS25645 a57b55ff5dd67fce2a4ff262242d9be7 316 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 187 206 5.8E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS25645 a57b55ff5dd67fce2a4ff262242d9be7 316 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 187 206 1.2E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS25645 a57b55ff5dd67fce2a4ff262242d9be7 316 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 103 114 1.2E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS25645 a57b55ff5dd67fce2a4ff262242d9be7 316 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 162 1.2E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR BWK49_RS13170 33a861be00d8f5e03ba3985c97bec5af 340 Gene3D G3DSA:2.120.10.30 77 160 1.1E-17 T 06-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like BWK49_RS13170 33a861be00d8f5e03ba3985c97bec5af 340 Gene3D G3DSA:2.120.10.30 200 326 1.1E-17 T 06-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like BWK49_RS13170 33a861be00d8f5e03ba3985c97bec5af 340 SUPERFAMILY SSF63829 96 338 1.5E-19 T 06-07-2017 BWK49_RS24100 4897e8dda89fb37047b73eee0ef483bf 478 SUPERFAMILY SSF51905 7 271 4.53E-16 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS24100 4897e8dda89fb37047b73eee0ef483bf 478 Gene3D G3DSA:3.50.50.60 3 227 7.1E-11 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS00600 dba8a8c9333fd61a5cf2b9c280fa83ec 523 Pfam PF02470 MlaD protein 46 126 4.7E-7 T 06-07-2017 IPR003399 Mce/MlaD BWK49_RS00600 dba8a8c9333fd61a5cf2b9c280fa83ec 523 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 174 387 1.5E-12 T 06-07-2017 IPR024516 Mammalian cell entry, C-terminal BWK49_RS06620 42e067922f0bcf0620c115da6dbe7ebc 311 SUPERFAMILY SSF52980 177 281 2.57E-6 T 06-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 BWK49_RS05595 02fbac02ef1a667285904fb32bd24f66 103 Pfam PF02371 Transposase IS116/IS110/IS902 family 2 69 2.4E-12 T 06-07-2017 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 BWK49_RS24450 75e11cb6071a2b32be9d3a6cd030d21e 151 Pfam PF11259 Protein of unknown function (DUF3060) 86 144 3.4E-22 T 06-07-2017 IPR021417 Protein of unknown function DUF3060 BWK49_RS13845 20ab47ac48272d8fdc2fc1bee0cfc5c4 435 Pfam PF01757 Acyltransferase family 14 355 1.5E-15 T 06-07-2017 IPR002656 Acyltransferase 3 GO:0016747 BWK49_RS25150 00d20c4a785908bde3444dbeeca901c6 259 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 21 237 3.0E-40 T 06-07-2017 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 BWK49_RS28550 cb882d8bd5aa3985fa141f0b02f123d0 465 Pfam PF13701 Transposase DDE domain group 1 8 462 5.9E-66 T 06-07-2017 IPR025668 Transposase DDE domain BWK49_RS23965 3c0e3fe2a3dba430e72f0d145796a23f 469 Pfam PF08817 WXG100 protein secretion system (Wss), protein YukD 19 93 9.8E-15 T 06-07-2017 IPR024962 YukD-like BWK49_RS23965 3c0e3fe2a3dba430e72f0d145796a23f 469 TIGRFAM TIGR03920 T7SS_EccD: type VII secretion integral membrane protein EccD 22 465 8.4E-66 T 06-07-2017 IPR006707 Type VII secretion system membrane protein EccD BWK49_RS13325 9874594ea20af5be90ab147a64ba343a 523 Pfam PF02470 MlaD protein 46 124 1.8E-6 T 06-07-2017 IPR003399 Mce/MlaD BWK49_RS13325 9874594ea20af5be90ab147a64ba343a 523 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 194 384 3.2E-15 T 06-07-2017 IPR024516 Mammalian cell entry, C-terminal BWK49_RS26910 eeef86963c8829ccfcbd73308e3ceeb8 432 Pfam PF11271 Protein of unknown function (DUF3068) 6 337 9.5E-94 T 06-07-2017 IPR021424 Protein of unknown function DUF3068 BWK49_RS19240 81e4c0c64d911d0fcbf8c83efbd86b10 112 Pfam PF05305 Protein of unknown function (DUF732) 6 103 6.9E-25 T 06-07-2017 IPR007969 Domain of unknown function DUF732 BWK49_RS00565 a46aa660c5d13fe1c69dc8b237f96f55 194 SUPERFAMILY SSF55729 2 161 1.92E-24 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase BWK49_RS00565 a46aa660c5d13fe1c69dc8b237f96f55 194 Pfam PF13420 Acetyltransferase (GNAT) domain 2 152 1.1E-24 T 06-07-2017 BWK49_RS00565 a46aa660c5d13fe1c69dc8b237f96f55 194 Gene3D G3DSA:3.40.630.30 2 163 7.7E-31 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase BWK49_RS07035 7b5d503c815bb5605030085421a96534 201 Pfam PF08044 Domain of unknown function (DUF1707) 18 69 6.5E-15 T 06-07-2017 IPR012551 Protein of unknown function DUF1707 BWK49_RS22050 4138a4d6abf6bd88d7959b92004e8e98 526 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 7 499 3.5E-163 T 06-07-2017 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS22050 4138a4d6abf6bd88d7959b92004e8e98 526 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 140 159 6.6E-32 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS22050 4138a4d6abf6bd88d7959b92004e8e98 526 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 339 358 6.6E-32 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS22050 4138a4d6abf6bd88d7959b92004e8e98 526 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 251 275 6.6E-32 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS22050 4138a4d6abf6bd88d7959b92004e8e98 526 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 171 195 6.6E-32 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS22050 4138a4d6abf6bd88d7959b92004e8e98 526 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 391 417 6.6E-32 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS22050 4138a4d6abf6bd88d7959b92004e8e98 526 Pfam PF00361 Proton-conducting membrane transporter 134 431 1.7E-65 T 06-07-2017 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS03840 71e614f95fb3acb570324f94e363000d 394 Pfam PF00144 Beta-lactamase 33 384 3.8E-69 T 06-07-2017 IPR001466 Beta-lactamase-related BWK49_RS03840 71e614f95fb3acb570324f94e363000d 394 SUPERFAMILY SSF56601 21 391 1.66E-73 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like BWK49_RS03840 71e614f95fb3acb570324f94e363000d 394 Gene3D G3DSA:3.40.710.10 24 393 1.2E-76 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like BWK49_RS25435 355ad8174104961bef375eb2d88074f7 87 Pfam PF10724 Protein of unknown function (DUF2516) 1 84 3.4E-26 T 06-07-2017 IPR019662 Protein of unknown function DUF2516 BWK49_RS26905 d0583e22f6bfba796b2424d458271779 411 Pfam PF01757 Acyltransferase family 39 373 2.7E-28 T 06-07-2017 IPR002656 Acyltransferase 3 GO:0016747 BWK49_RS19570 3d2d5b2c6ed65fff1d1c4f738c63ca32 173 Gene3D G3DSA:1.10.10.10 19 63 3.1E-10 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS19570 3d2d5b2c6ed65fff1d1c4f738c63ca32 173 Gene3D G3DSA:1.10.10.10 65 108 3.2E-7 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS19570 3d2d5b2c6ed65fff1d1c4f738c63ca32 173 Pfam PF02631 RecX family 41 160 2.3E-27 T 06-07-2017 IPR003783 Regulatory protein RecX GO:0006282 BWK49_RS19570 3d2d5b2c6ed65fff1d1c4f738c63ca32 173 Hamap MF_01114 Regulatory protein RecX [recX]. 14 167 15.171 T 06-07-2017 IPR003783 Regulatory protein RecX GO:0006282 BWK49_RS21710 0a9278138717b78a8b13ebc51207b6ca 168 Pfam PF10698 Protein of unknown function (DUF2505) 9 164 4.3E-38 T 06-07-2017 IPR019639 Protein of unknown function DUF2505 BWK49_RS00980 bc4c7f3aaef7c71d8252b55955b56d7b 167 SUPERFAMILY SSF81296 26 120 1.77E-23 T 06-07-2017 IPR014756 Immunoglobulin E-set BWK49_RS00980 bc4c7f3aaef7c71d8252b55955b56d7b 167 Gene3D G3DSA:2.60.40.1220 26 120 1.7E-24 T 06-07-2017 IPR014755 Copper resistance protein CopC/internalin, immunoglobulin-like BWK49_RS00980 bc4c7f3aaef7c71d8252b55955b56d7b 167 Pfam PF04234 CopC domain 27 119 5.1E-21 T 06-07-2017 IPR007348 CopC domain GO:0005507|GO:0042597|GO:0046688 BWK49_RS23295 0ad677a246df3895eeb5300585121862 379 SUPERFAMILY SSF140459 5 169 1.36E-53 T 06-07-2017 BWK49_RS23295 0ad677a246df3895eeb5300585121862 379 Pfam PF00823 PPE family 5 159 2.3E-54 T 06-07-2017 IPR000030 PPE family BWK49_RS01560 c8e981f6a3dc604fa1b9e8708c0d1644 351 Gene3D G3DSA:3.10.129.10 10 169 9.3E-12 T 06-07-2017 IPR029069 HotDog domain BWK49_RS01560 c8e981f6a3dc604fa1b9e8708c0d1644 351 Gene3D G3DSA:3.10.129.10 214 346 7.5E-11 T 06-07-2017 IPR029069 HotDog domain BWK49_RS01560 c8e981f6a3dc604fa1b9e8708c0d1644 351 SUPERFAMILY SSF54637 9 176 1.92E-15 T 06-07-2017 IPR029069 HotDog domain BWK49_RS01560 c8e981f6a3dc604fa1b9e8708c0d1644 351 Pfam PF13452 N-terminal half of MaoC dehydratase 26 163 2.5E-13 T 06-07-2017 BWK49_RS01560 c8e981f6a3dc604fa1b9e8708c0d1644 351 SUPERFAMILY SSF54637 215 350 1.07E-12 T 06-07-2017 IPR029069 HotDog domain BWK49_RS18250 461cc6904c41158bd439467f9a2806a5 77 PRINTS PR01651 Protein-export SecG membrane protein signature 23 37 7.1E-5 T 06-07-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 BWK49_RS18250 461cc6904c41158bd439467f9a2806a5 77 PRINTS PR01651 Protein-export SecG membrane protein signature 54 76 7.1E-5 T 06-07-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 BWK49_RS18250 461cc6904c41158bd439467f9a2806a5 77 PRINTS PR01651 Protein-export SecG membrane protein signature 3 23 7.1E-5 T 06-07-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 BWK49_RS18250 461cc6904c41158bd439467f9a2806a5 77 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 3 73 1.9E-18 T 06-07-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 BWK49_RS18250 461cc6904c41158bd439467f9a2806a5 77 Pfam PF03840 Preprotein translocase SecG subunit 5 72 3.6E-15 T 06-07-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 BWK49_RS17675 a4e1a56aa13545e352730d4f4bab2914 242 Gene3D G3DSA:3.40.50.150 22 213 2.8E-9 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS17675 a4e1a56aa13545e352730d4f4bab2914 242 SUPERFAMILY SSF53335 15 239 8.31E-41 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS17675 a4e1a56aa13545e352730d4f4bab2914 242 Pfam PF04989 Cephalosporin hydroxylase 22 240 3.4E-96 T 06-07-2017 IPR007072 Rhamnosyl O-methyltransferase/Cephalosporin hydroxylase GO:0008168|GO:0008610 BWK49_RS16315 a9a0f8305e632739cf13b012d4c0b483 357 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 17 299 1.0E-48 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme BWK49_RS16315 a9a0f8305e632739cf13b012d4c0b483 357 Gene3D G3DSA:3.40.50.1100 47 146 2.6E-20 T 06-07-2017 BWK49_RS16315 a9a0f8305e632739cf13b012d4c0b483 357 SUPERFAMILY SSF53686 16 320 8.64E-66 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme BWK49_RS16315 a9a0f8305e632739cf13b012d4c0b483 357 Gene3D G3DSA:3.40.50.1100 147 313 4.5E-38 T 06-07-2017 BWK49_RS19165 d69955bd6722d4bedd524bf49ccdc9e7 267 Gene3D G3DSA:2.40.400.10 29 254 3.8E-60 T 06-07-2017 IPR023375 Acetoacetate decarboxylase beta barrel domain KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 BWK49_RS19165 d69955bd6722d4bedd524bf49ccdc9e7 267 Pfam PF06314 Acetoacetate decarboxylase (ADC) 9 235 2.9E-49 T 06-07-2017 IPR010451 Acetoacetate decarboxylase GO:0016829 KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 BWK49_RS19165 d69955bd6722d4bedd524bf49ccdc9e7 267 SUPERFAMILY SSF160104 29 227 1.57E-44 T 06-07-2017 BWK49_RS06415 91a9c103dab9fd2e5f06e415f598501f 95 Pfam PF03626 Prokaryotic Cytochrome C oxidase subunit IV 11 85 2.4E-9 T 06-07-2017 IPR005171 Cytochrome C oxidase subunit IV, prokaryotes GO:0016021 BWK49_RS05415 8d34068f4f5edb6353280f517904dac1 172 Gene3D G3DSA:1.10.10.60 5 49 8.8E-4 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 BWK49_RS05415 8d34068f4f5edb6353280f517904dac1 172 ProDom PD020942 TRANSPOSASE C TN554 TRANSPOSON TRANSPOSITION FOR DNA-BINDING TRANSPOSABLE DNA ELEMENT 41 109 8.0E-4 T 06-07-2017 BWK49_RS26305 115e6058864f1a16b93a6cfe09a79dec 224 Pfam PF11139 Sap, sulfolipid-1-addressing protein 12 220 7.1E-61 T 06-07-2017 IPR021315 Glycolipid exporter Gap/Sap BWK49_RS29070 7de20257cb6b5670ee4dc4b9d8dabc37 308 Pfam PF12642 Conjugative transposon protein TcpC 109 281 1.3E-14 T 06-07-2017 IPR024735 Conjugative transposon protein TcpC BWK49_RS14515 b80737d360a0662ef6bcdbb548c67094 135 Gene3D G3DSA:3.30.429.20 1 55 3.2E-5 T 06-07-2017 BWK49_RS14515 b80737d360a0662ef6bcdbb548c67094 135 SUPERFAMILY SSF55331 2 121 1.83E-7 T 06-07-2017 IPR014347 Tautomerase/MIF superfamily BWK49_RS11280 eb4433cc2e23e9f554d8f4196f5809ce 774 SUPERFAMILY SSF81442 277 751 1.44E-74 T 06-07-2017 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 BWK49_RS11280 eb4433cc2e23e9f554d8f4196f5809ce 774 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 283 725 2.2E-60 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 BWK49_RS29095 b22c837c8349c3d905950966eaf933d0 467 Gene3D G3DSA:3.40.50.300 19 103 8.2E-22 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS29095 b22c837c8349c3d905950966eaf933d0 467 Gene3D G3DSA:3.40.50.300 238 421 8.2E-22 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS29095 b22c837c8349c3d905950966eaf933d0 467 Pfam PF02534 Type IV secretory system Conjugative DNA transfer 14 398 1.8E-15 T 06-07-2017 IPR003688 Type IV secretion system protein TraG/VirD4 GO:0009291|GO:0016020 BWK49_RS29095 b22c837c8349c3d905950966eaf933d0 467 SUPERFAMILY SSF52540 25 353 3.84E-22 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS24665 d780ab19f4c27b93ac525a4a87ed0849 334 Pfam PF01734 Patatin-like phospholipase 13 217 3.7E-29 T 06-07-2017 IPR002641 Patatin/Phospholipase A2-related GO:0006629 BWK49_RS24665 d780ab19f4c27b93ac525a4a87ed0849 334 Gene3D G3DSA:3.40.1090.10 42 214 1.9E-11 T 06-07-2017 BWK49_RS24665 d780ab19f4c27b93ac525a4a87ed0849 334 SUPERFAMILY SSF52151 9 331 6.54E-37 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 BWK49_RS20695 6a8732f82124f966f5b7f8abc9c8156b 99 SUPERFAMILY SSF140459 8 81 6.28E-20 T 06-07-2017 BWK49_RS20695 6a8732f82124f966f5b7f8abc9c8156b 99 Pfam PF00934 PE family 1 93 3.2E-26 T 06-07-2017 IPR000084 PE-PGRS family, N-terminal BWK49_RS21675 b675c4df43e24ecb231f01a7ce8ceaac 134 Pfam PF14087 Domain of unknown function (DUF4267) 11 116 4.3E-8 T 06-07-2017 IPR025363 Protein of unknown function DUF4267 BWK49_RS01375 4c607bdef7059bcce835e8a59f5bce7b 161 Gene3D G3DSA:1.10.260.40 73 106 4.8E-5 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 BWK49_RS17185 a56ce455f9ef30d8e5a4daab8b8e85bf 160 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 22 56 1.4E-9 T 06-07-2017 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal BWK49_RS17185 a56ce455f9ef30d8e5a4daab8b8e85bf 160 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 58 125 4.4E-13 T 06-07-2017 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal BWK49_RS17185 a56ce455f9ef30d8e5a4daab8b8e85bf 160 SUPERFAMILY SSF50249 23 129 1.46E-19 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS26190 9720cb5193fb8e02d628944ee54c8455 124 SUPERFAMILY SSF54427 1 102 2.03E-11 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS26190 9720cb5193fb8e02d628944ee54c8455 124 Pfam PF12680 SnoaL-like domain 9 97 1.9E-7 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain BWK49_RS26190 9720cb5193fb8e02d628944ee54c8455 124 Gene3D G3DSA:3.10.450.50 4 104 9.4E-9 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS12440 2a5bebb1aabd8585dcd04dad8408c068 530 Pfam PF01494 FAD binding domain 15 364 1.3E-85 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 BWK49_RS12440 2a5bebb1aabd8585dcd04dad8408c068 530 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 353 369 1.5E-37 T 06-07-2017 BWK49_RS12440 2a5bebb1aabd8585dcd04dad8408c068 530 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 173 188 1.5E-37 T 06-07-2017 BWK49_RS12440 2a5bebb1aabd8585dcd04dad8408c068 530 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 16 38 1.5E-37 T 06-07-2017 BWK49_RS12440 2a5bebb1aabd8585dcd04dad8408c068 530 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 335 353 1.5E-37 T 06-07-2017 BWK49_RS12440 2a5bebb1aabd8585dcd04dad8408c068 530 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 302 317 1.5E-37 T 06-07-2017 BWK49_RS12440 2a5bebb1aabd8585dcd04dad8408c068 530 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 317 333 1.5E-37 T 06-07-2017 BWK49_RS12440 2a5bebb1aabd8585dcd04dad8408c068 530 SUPERFAMILY SSF51905 289 369 2.91E-57 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS12440 2a5bebb1aabd8585dcd04dad8408c068 530 SUPERFAMILY SSF51905 15 194 2.91E-57 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS12440 2a5bebb1aabd8585dcd04dad8408c068 530 Gene3D G3DSA:3.50.50.60 14 80 2.6E-55 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS12440 2a5bebb1aabd8585dcd04dad8408c068 530 Gene3D G3DSA:3.50.50.60 115 199 2.6E-55 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS12440 2a5bebb1aabd8585dcd04dad8408c068 530 Gene3D G3DSA:3.50.50.60 290 366 2.6E-55 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 BWK49_RS02445 8e783a2638baa0e7d8cf6f4999d8313e 279 SUPERFAMILY SSF103473 2 148 2.62E-6 T 06-07-2017 IPR020846 Major facilitator superfamily domain BWK49_RS24635 dec8e99af49fee98fce2275c777bb817 68 Pfam PF09957 Bacterial antitoxin of type II TA system, VapB 3 53 1.9E-16 T 06-07-2017 IPR019239 Bacterial antitoxin of type II TA system, VapB BWK49_RS18865 2e0147a3dfb27e58b74a4f7b7b6e20f8 151 Pfam PF03994 Domain of Unknown Function (DUF350) 25 79 9.3E-14 T 06-07-2017 IPR007140 Protein of unknown function DUF350 BWK49_RS18865 2e0147a3dfb27e58b74a4f7b7b6e20f8 151 Pfam PF03994 Domain of Unknown Function (DUF350) 96 150 4.2E-7 T 06-07-2017 IPR007140 Protein of unknown function DUF350 BWK49_RS21705 191cf89129c740393c831be9da3d873a 287 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 45 222 5.4E-30 T 06-07-2017 IPR008775 Phytanoyl-CoA dioxygenase BWK49_RS21705 191cf89129c740393c831be9da3d873a 287 Gene3D G3DSA:2.60.120.620 33 238 1.1E-39 T 06-07-2017 BWK49_RS21705 191cf89129c740393c831be9da3d873a 287 SUPERFAMILY SSF51197 35 277 3.75E-59 T 06-07-2017 BWK49_RS02965 763b3478921e5382a4abb547d7a2268a 113 Pfam PF10066 Uncharacterized conserved protein (DUF2304) 3 107 2.8E-28 T 06-07-2017 IPR019277 Protein of unknown function DUF2304 BWK49_RS25465 a5a49ec030b0f4d160aca039f4cabdac 286 Pfam PF02353 Mycolic acid cyclopropane synthetase 5 282 2.1E-110 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS25465 a5a49ec030b0f4d160aca039f4cabdac 286 Gene3D G3DSA:3.40.50.150 5 285 9.8E-83 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS25465 a5a49ec030b0f4d160aca039f4cabdac 286 PIRSF PIRSF003085 6 286 5.8E-98 T 06-07-2017 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 BWK49_RS25465 a5a49ec030b0f4d160aca039f4cabdac 286 SUPERFAMILY SSF53335 12 286 3.68E-73 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS06430 117782d7ff49d77a2f7f61442f3b9b2b 121 PIRSF PIRSF021591 1 121 9.1E-55 T 06-07-2017 IPR016793 Uncharacterised conserved protein UCP021591 BWK49_RS18530 60f064b82e21224c2c5d36a013bfe683 76 SUPERFAMILY SSF54862 9 69 1.94E-16 T 06-07-2017 BWK49_RS18530 60f064b82e21224c2c5d36a013bfe683 76 Gene3D G3DSA:3.30.70.20 13 69 1.7E-16 T 06-07-2017 BWK49_RS18530 60f064b82e21224c2c5d36a013bfe683 76 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 52 63 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site BWK49_RS18530 60f064b82e21224c2c5d36a013bfe683 76 Pfam PF12838 4Fe-4S dicluster domain 20 66 1.5E-9 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain BWK49_RS26830 de45c64bb7629eccd150b52898067bd0 70 Pfam PF11160 Protein of unknown function (DUF2945) 8 68 2.6E-26 T 06-07-2017 IPR021331 Protein of unknown function DUF2945 BWK49_RS18985 e761da31b9fd1d28e516fce54b8047ed 279 Gene3D G3DSA:3.40.50.150 39 274 6.7E-21 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS18985 e761da31b9fd1d28e516fce54b8047ed 279 Pfam PF08241 Methyltransferase domain 60 157 7.4E-10 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 BWK49_RS18985 e761da31b9fd1d28e516fce54b8047ed 279 SUPERFAMILY SSF53335 30 273 1.23E-25 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS03170 4ccaf35c7b2064f86e8aae565a99b1a7 162 SMART SM01058 2 112 1.8E-34 T 06-07-2017 IPR003711 CarD-like/TRCF domain BWK49_RS03170 4ccaf35c7b2064f86e8aae565a99b1a7 162 SUPERFAMILY SSF141259 3 66 4.18E-15 T 06-07-2017 IPR003711 CarD-like/TRCF domain BWK49_RS03170 4ccaf35c7b2064f86e8aae565a99b1a7 162 Pfam PF02559 CarD-like/TRCF domain 3 110 9.8E-17 T 06-07-2017 IPR003711 CarD-like/TRCF domain BWK49_RS15870 58d14c5b4196083b231ab19cc5bc66eb 94 Gene3D G3DSA:2.20.28.30 9 33 9.4E-5 T 06-07-2017 IPR006591 RNA polymerase archaeal subunit P/eukaryotic subunit RPABC4 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 BWK49_RS28865 8f1bb2c88c10e58fdea833b503255847 635 Pfam PF03457 Helicase associated domain 50 110 1.4E-13 T 06-07-2017 IPR005114 Helicase-associated BWK49_RS28865 8f1bb2c88c10e58fdea833b503255847 635 Pfam PF03457 Helicase associated domain 339 399 2.1E-15 T 06-07-2017 IPR005114 Helicase-associated BWK49_RS28865 8f1bb2c88c10e58fdea833b503255847 635 Pfam PF03457 Helicase associated domain 268 329 1.9E-16 T 06-07-2017 IPR005114 Helicase-associated BWK49_RS28865 8f1bb2c88c10e58fdea833b503255847 635 Pfam PF03457 Helicase associated domain 489 547 9.5E-17 T 06-07-2017 IPR005114 Helicase-associated BWK49_RS28865 8f1bb2c88c10e58fdea833b503255847 635 Pfam PF03457 Helicase associated domain 120 181 1.1E-16 T 06-07-2017 IPR005114 Helicase-associated BWK49_RS28865 8f1bb2c88c10e58fdea833b503255847 635 Pfam PF03457 Helicase associated domain 192 252 3.8E-17 T 06-07-2017 IPR005114 Helicase-associated BWK49_RS28865 8f1bb2c88c10e58fdea833b503255847 635 Pfam PF03457 Helicase associated domain 410 471 1.8E-16 T 06-07-2017 IPR005114 Helicase-associated BWK49_RS28865 8f1bb2c88c10e58fdea833b503255847 635 Pfam PF03457 Helicase associated domain 557 618 3.0E-17 T 06-07-2017 IPR005114 Helicase-associated BWK49_RS28975 d5692f164062d6bfd7151108976eedd8 98 SUPERFAMILY SSF140459 7 81 7.85E-15 T 06-07-2017 BWK49_RS28975 d5692f164062d6bfd7151108976eedd8 98 Pfam PF00934 PE family 2 91 2.2E-18 T 06-07-2017 IPR000084 PE-PGRS family, N-terminal BWK49_RS21825 0643ca94e647821b78b71f1362ac7035 297 PIRSF PIRSF003097 1 297 1.1E-56 T 06-07-2017 IPR004513 Cell division protein FtsX GO:0007049|GO:0016021 BWK49_RS21825 0643ca94e647821b78b71f1362ac7035 297 Pfam PF02687 FtsX-like permease family 176 290 2.1E-11 T 06-07-2017 IPR003838 ABC transporter permease protein domain GO:0016020 BWK49_RS27125 f08f085338347b011017fb26848c52aa 414 Pfam PF07690 Major Facilitator Superfamily 25 341 1.1E-28 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 BWK49_RS27125 f08f085338347b011017fb26848c52aa 414 SUPERFAMILY SSF103473 11 398 4.19E-49 T 06-07-2017 IPR020846 Major facilitator superfamily domain BWK49_RS27125 f08f085338347b011017fb26848c52aa 414 Gene3D G3DSA:1.20.1250.20 215 395 4.3E-15 T 06-07-2017 BWK49_RS27125 f08f085338347b011017fb26848c52aa 414 Gene3D G3DSA:1.20.1250.20 21 196 4.6E-22 T 06-07-2017 BWK49_RS16265 cb93446718249e96b5273db85db955eb 187 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 19 158 1.6E-9 T 06-07-2017 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS05075 c2ad5ccd3d672b25a71af5e733fc0d91 402 Pfam PF01548 Transposase 8 164 4.4E-45 T 06-07-2017 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 BWK49_RS05075 c2ad5ccd3d672b25a71af5e733fc0d91 402 Pfam PF02371 Transposase IS116/IS110/IS902 family 271 356 3.7E-26 T 06-07-2017 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 BWK49_RS12670 44916cbe5efb9651507ddbd2584e7b1d 99 Pfam PF10708 Protein of unknown function (DUF2510) 67 97 1.5E-8 T 06-07-2017 IPR018929 Domain of unknown function DUF2510 BWK49_RS11945 1f2c64533066cbc0ca8b76cffc2436f2 105 Pfam PF13466 STAS domain 19 72 1.8E-7 T 06-07-2017 IPR002645 STAS domain BWK49_RS11945 1f2c64533066cbc0ca8b76cffc2436f2 105 SUPERFAMILY SSF52091 13 97 1.94E-12 T 06-07-2017 IPR002645 STAS domain BWK49_RS11945 1f2c64533066cbc0ca8b76cffc2436f2 105 Gene3D G3DSA:3.30.750.24 11 74 4.7E-11 T 06-07-2017 IPR002645 STAS domain BWK49_RS10100 efde041f17a9568f234b86f0518230e6 352 SUPERFAMILY SSF51735 9 146 2.97E-11 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS10100 efde041f17a9568f234b86f0518230e6 352 Gene3D G3DSA:3.40.50.720 5 174 5.6E-23 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS03355 7e40b5360c1703652d3e7c11e7041c17 357 SUPERFAMILY SSF51412 305 348 2.75E-58 T 06-07-2017 BWK49_RS03355 7e40b5360c1703652d3e7c11e7041c17 357 SUPERFAMILY SSF51412 4 265 2.75E-58 T 06-07-2017 BWK49_RS03355 7e40b5360c1703652d3e7c11e7041c17 357 Pfam PF03060 Nitronate monooxygenase 6 342 8.8E-106 T 06-07-2017 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 BWK49_RS03355 7e40b5360c1703652d3e7c11e7041c17 357 Gene3D G3DSA:3.20.20.70 3 337 3.3E-68 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 BWK49_RS29085 84e6501282999d3f55bbd0e4444693a7 144 Gene3D G3DSA:3.20.20.60 53 119 6.4E-4 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 BWK49_RS21600 c2fe377be883b3e19e5a79bc662d3bad 68 Gene3D G3DSA:1.10.1220.10 3 65 7.5E-6 T 06-07-2017 IPR013321 Arc-type ribbon-helix-helix GO:0006355 BWK49_RS12535 76d174e42033c53adf68f4cc2f288162 342 Gene3D G3DSA:3.40.640.10 35 242 7.8E-44 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 BWK49_RS12535 76d174e42033c53adf68f4cc2f288162 342 Pfam PF00155 Aminotransferase class I and II 44 323 9.0E-24 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 BWK49_RS12535 76d174e42033c53adf68f4cc2f288162 342 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 200 213 - T 06-07-2017 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 BWK49_RS12535 76d174e42033c53adf68f4cc2f288162 342 SUPERFAMILY SSF53383 21 337 6.04E-53 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase BWK49_RS12535 76d174e42033c53adf68f4cc2f288162 342 Gene3D G3DSA:3.90.1150.10 243 340 1.6E-18 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 BWK49_RS19310 b9c86551607276b66dd14cd319dd8c42 218 Pfam PF11452 Protein of unknown function (DUF3000) 31 210 1.4E-72 T 06-07-2017 IPR021555 Protein of unknown function DUF3000 BWK49_RS15995 6ced9bfe7d478b0c91c00e1be97c48b8 412 Pfam PF00487 Fatty acid desaturase 69 333 1.9E-29 T 06-07-2017 IPR005804 Fatty acid desaturase domain GO:0006629 BWK49_RS02240 a83c88a72da0e245761e39a7072b7d7b 161 Pfam PF05154 TM2 domain 80 143 3.5E-9 T 06-07-2017 IPR007829 TM2 domain BWK49_RS11650 3fb82d97feb84b23eb5249ab112cbc3b 457 Pfam PF01523 Putative modulator of DNA gyrase 26 320 4.6E-28 T 06-07-2017 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 BWK49_RS11650 3fb82d97feb84b23eb5249ab112cbc3b 457 SUPERFAMILY SSF111283 4 450 5.36E-65 T 06-07-2017 BWK49_RS01250 a3f9ddc565c6e3f8eb47e8686f40e2fe 140 Pfam PF04138 GtrA-like protein 21 137 1.8E-19 T 06-07-2017 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 BWK49_RS28645 68d99f101efda2bbfea8c23e370cec12 91 SUPERFAMILY SSF143011 6 87 8.11E-14 T 06-07-2017 BWK49_RS28645 68d99f101efda2bbfea8c23e370cec12 91 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 9 89 2.2E-6 T 06-07-2017 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family BWK49_RS22305 ebe80a50d7a698d324f92d74d17eb270 149 Gene3D G3DSA:2.60.40.790 7 128 4.1E-27 T 06-07-2017 IPR008978 HSP20-like chaperone BWK49_RS22305 ebe80a50d7a698d324f92d74d17eb270 149 Pfam PF00011 Hsp20/alpha crystallin family 32 128 9.3E-23 T 06-07-2017 IPR002068 Alpha crystallin/Hsp20 domain BWK49_RS22305 ebe80a50d7a698d324f92d74d17eb270 149 SUPERFAMILY SSF49764 5 128 1.65E-29 T 06-07-2017 IPR008978 HSP20-like chaperone BWK49_RS03700 d5cb29c3b5b6fffb8f3524ae5a0ce7bf 496 ProSitePatterns PS00571 Amidases signature. 149 180 - T 06-07-2017 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 BWK49_RS03700 d5cb29c3b5b6fffb8f3524ae5a0ce7bf 496 Pfam PF01425 Amidase 28 474 1.7E-86 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 BWK49_RS03700 d5cb29c3b5b6fffb8f3524ae5a0ce7bf 496 SUPERFAMILY SSF75304 3 391 7.72E-117 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 BWK49_RS03700 d5cb29c3b5b6fffb8f3524ae5a0ce7bf 496 SUPERFAMILY SSF75304 427 483 7.72E-117 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 BWK49_RS03700 d5cb29c3b5b6fffb8f3524ae5a0ce7bf 496 Gene3D G3DSA:3.90.1300.10 427 489 1.0E-116 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 BWK49_RS03700 d5cb29c3b5b6fffb8f3524ae5a0ce7bf 496 Gene3D G3DSA:3.90.1300.10 4 393 1.0E-116 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 BWK49_RS03865 1e051c711b88858faca1f5acafc741ba 249 PIRSF PIRSF018008 1 247 7.4E-79 T 06-07-2017 IPR008306 Uncharacterised conserved protein UCP018008 BWK49_RS03865 1e051c711b88858faca1f5acafc741ba 249 Pfam PF04250 Protein of unknown function (DUF429) 5 220 2.2E-36 T 06-07-2017 IPR007362 Protein of unknown function DUF429 BWK49_RS24775 6afe2128d2336f26e562c164989b691b 295 Gene3D G3DSA:3.40.50.1010 6 180 1.2E-37 T 06-07-2017 IPR029060 PIN domain-like BWK49_RS24775 6afe2128d2336f26e562c164989b691b 295 Pfam PF01936 NYN domain 8 176 5.9E-24 T 06-07-2017 IPR021139 NYN domain, limkain-b1-type BWK49_RS24775 6afe2128d2336f26e562c164989b691b 295 Pfam PF12872 OST-HTH/LOTUS domain 227 288 5.0E-12 T 06-07-2017 IPR025605 OST-HTH/LOTUS domain BWK49_RS04315 18df1aa9771051559c3644a026327c65 472 Pfam PF10774 Domain of unknown function (DUF4226) 41 150 5.2E-22 T 06-07-2017 IPR019710 Protein of unknown function DUF4226 BWK49_RS00470 5652ca79b21868b9d546ca21632bb5c6 228 Gene3D G3DSA:3.40.109.10 5 202 5.7E-41 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 BWK49_RS00470 5652ca79b21868b9d546ca21632bb5c6 228 SUPERFAMILY SSF55469 6 68 1.83E-41 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 BWK49_RS00470 5652ca79b21868b9d546ca21632bb5c6 228 SUPERFAMILY SSF55469 100 206 1.83E-41 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 BWK49_RS00470 5652ca79b21868b9d546ca21632bb5c6 228 Pfam PF00881 Nitroreductase family 15 183 1.0E-31 T 06-07-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 BWK49_RS20310 4f41412139dfbaf70c36abc24cd978ee 139 Pfam PF13577 SnoaL-like domain 6 129 9.2E-29 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain BWK49_RS20310 4f41412139dfbaf70c36abc24cd978ee 139 SUPERFAMILY SSF54427 4 135 4.97E-35 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS20310 4f41412139dfbaf70c36abc24cd978ee 139 Gene3D G3DSA:3.10.450.50 6 136 1.8E-42 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS12930 9806cdc63185e89f00f041b09e8bb1ee 271 Pfam PF13699 Domain of unknown function (DUF4157) 122 159 4.0E-5 T 06-07-2017 IPR025295 Domain of unknown function DUF4157 BWK49_RS20950 5c55d44a379f10934b49f40bd357a5d0 118 ProDom PD072817 ANTIGEN WEIGHT MOLECULAR LOW CFP-6 CGL1269 SEQUENCING DIRECT 7 118 1.0E-45 T 06-07-2017 IPR020535 Low molecular weight antigen Cfp6 BWK49_RS20950 5c55d44a379f10934b49f40bd357a5d0 118 Pfam PF10756 Bacterial PH domain 45 115 4.1E-20 T 06-07-2017 IPR019692 Protein of unknown function DUF2581 BWK49_RS27170 26eff14492db3fda5570b30dd8049051 249 Pfam PF10979 Protein of unknown function (DUF2786) 5 43 3.2E-12 T 06-07-2017 IPR024498 Domain of unknown function DUF2786 BWK49_RS27170 26eff14492db3fda5570b30dd8049051 249 ProDom PD120223 SCO3432 GENE ML2604 GP79 GP77 CGL2230 MB0190 1 247 8.0E-94 T 06-07-2017 BWK49_RS28995 6888053dc2a198af370669f6fcfeda9e 306 Pfam PF14011 EspG family 18 288 2.8E-31 T 06-07-2017 IPR025734 EspG family BWK49_RS03340 f03ca58f7f95f9e07c96d6054deda8cb 302 Pfam PF04480 Protein of unknown function (DUF559) 215 277 1.4E-4 T 06-07-2017 IPR007569 Domain of unknown function DUF559 BWK49_RS03340 f03ca58f7f95f9e07c96d6054deda8cb 302 SUPERFAMILY SSF52980 176 279 9.65E-7 T 06-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 BWK49_RS02815 295934f2452f33ce4c6a8ed34928489c 172 Pfam PF07332 Putative Actinobacterial Holin-X, holin superfamily III 32 145 1.9E-32 T 06-07-2017 IPR009937 Putative Actinobacterial Holin-X, holin superfamily III BWK49_RS17755 e8be149873bcbb10c9dcd1d26aa17ff1 330 SUPERFAMILY SSF52540 19 65 3.64E-15 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS17755 e8be149873bcbb10c9dcd1d26aa17ff1 330 SUPERFAMILY SSF52540 107 237 3.64E-15 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase BWK49_RS16245 9169e0eddaf18932c63c9f5507401170 126 Pfam PF04075 Domain of unknown function (DUF385) 8 119 1.0E-32 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 BWK49_RS16245 9169e0eddaf18932c63c9f5507401170 126 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 11 121 1.2E-28 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 BWK49_RS01075 63d5e0c9b95f63a4ed37964650db5d80 165 Pfam PF11196 Protein of unknown function (DUF2834) 41 148 5.0E-32 T 06-07-2017 IPR021362 Protein of unknown function DUF2834 BWK49_RS03880 9e284ae0cc930586457d7bd461ca25d2 340 Pfam PF03595 Voltage-dependent anion channel 12 318 4.8E-29 T 06-07-2017 IPR004695 Voltage-dependent anion channel GO:0016021|GO:0055085 BWK49_RS21150 70db02b528db6732e8bf16c6a5c8b8ab 103 TIGRFAM TIGR03462 CarR_dom_SF: lycopene cyclase domain 6 96 2.0E-21 T 06-07-2017 IPR017825 Lycopene cyclase domain GO:0016872 KEGG: 00906+2.5.1.32+5.5.1.19|MetaCyc: PWY-5943|MetaCyc: PWY-5947|MetaCyc: PWY-7591 BWK49_RS27215 a31a05820ccbeac99021a09f6d136310 221 Pfam PF06912 Protein of unknown function (DUF1275) 4 202 3.9E-32 T 06-07-2017 IPR010699 Protein of unknown function DUF1275 BWK49_RS27445 f6c041b1839b42eb5fea608828557b98 153 SUPERFAMILY SSF54427 3 148 3.29E-71 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS27445 f6c041b1839b42eb5fea608828557b98 153 Pfam PF07080 Protein of unknown function (DUF1348) 5 142 1.7E-67 T 06-07-2017 IPR009783 Protein of unknown function DUF1348 BWK49_RS27445 f6c041b1839b42eb5fea608828557b98 153 Gene3D G3DSA:3.10.450.50 12 144 6.7E-66 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS23545 ccd664f56e6ed295c19761e5bdf6aead 93 Pfam PF11222 Protein of unknown function (DUF3017) 13 86 7.5E-21 T 06-07-2017 IPR021385 Protein of unknown function DUF3017 BWK49_RS02375 2a53e926c1cd8be9864e7ddb1742bd81 153 Pfam PF11196 Protein of unknown function (DUF2834) 23 117 1.5E-21 T 06-07-2017 IPR021362 Protein of unknown function DUF2834 BWK49_RS18185 e359b8082d18f5095af49c9f7be4159f 317 Pfam PF02628 Cytochrome oxidase assembly protein 27 298 8.2E-14 T 06-07-2017 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 BWK49_RS09055 4577c643865fd40dc0f6a630df09ace3 226 Hamap MF_00722 Endonuclease NucS [nucS]. 4 218 31.452 T 06-07-2017 IPR002793 Endonuclease NucS BWK49_RS09055 4577c643865fd40dc0f6a630df09ace3 226 Pfam PF01939 Protein of unknown function DUF91 2 226 2.5E-98 T 06-07-2017 IPR002793 Endonuclease NucS BWK49_RS16645 17800a3107e872a57489ef407a905400 314 Pfam PF11382 Copper transport outer membrane protein, MctB 1 311 1.8E-95 T 06-07-2017 IPR021522 Copper transporter MctB GO:0006810 BWK49_RS21885 942d5b6ef69fafe125f848c5631fd815 776 SUPERFAMILY SSF81442 273 749 3.79E-78 T 06-07-2017 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 BWK49_RS21885 942d5b6ef69fafe125f848c5631fd815 776 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 280 724 4.6E-64 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 BWK49_RS09295 89441484e73819bdfdde911a28eeceb2 400 Pfam PF04909 Amidohydrolase 90 393 1.8E-27 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 BWK49_RS09295 89441484e73819bdfdde911a28eeceb2 400 SUPERFAMILY SSF51556 6 35 2.19E-64 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS09295 89441484e73819bdfdde911a28eeceb2 400 SUPERFAMILY SSF51556 92 393 2.19E-64 T 06-07-2017 IPR032466 Metal-dependent hydrolase BWK49_RS09295 89441484e73819bdfdde911a28eeceb2 400 Gene3D G3DSA:3.20.20.140 9 394 2.7E-73 T 06-07-2017 BWK49_RS18910 41ee764cad367c011605bd5bb7b83fc6 213 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 71 93 - T 06-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 BWK49_RS18910 41ee764cad367c011605bd5bb7b83fc6 213 Pfam PF01066 CDP-alcohol phosphatidyltransferase 29 93 1.6E-10 T 06-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 BWK49_RS22605 be8e98d308b566268833fb8fade94260 452 Pfam PF10103 Zinicin-like metallopeptidase 73 421 3.0E-112 T 06-07-2017 IPR018766 Zinicin-like metallopeptidase type 2 BWK49_RS22605 be8e98d308b566268833fb8fade94260 452 TIGRFAM TIGR03624 TIGR03624: putative hydrolase 73 424 7.4E-122 T 06-07-2017 IPR018766 Zinicin-like metallopeptidase type 2 BWK49_RS22605 be8e98d308b566268833fb8fade94260 452 SUPERFAMILY SSF55486 72 424 3.81E-111 T 06-07-2017 BWK49_RS02910 736563a3f30305836b21b64a5ae8752e 124 TIGRFAM TIGR03816 tadE_like_DECH: helicase/secretion neighborhood TadE-like protein 14 118 3.5E-25 T 06-07-2017 IPR021202 Helicase/secretion neighbourhood TadE-like protein BWK49_RS02910 736563a3f30305836b21b64a5ae8752e 124 Pfam PF13400 Putative Flp pilus-assembly TadE/G-like 16 62 1.2E-8 T 06-07-2017 IPR028087 Putative Flp pilus-assembly TadG-like, N-terminal BWK49_RS17725 0d1c1745972b901938e0688ddc86141f 267 Pfam PF05711 Macrocin-O-methyltransferase (TylF) 88 231 1.3E-11 T 06-07-2017 IPR008884 Macrocin-O-methyltransferase BWK49_RS17725 0d1c1745972b901938e0688ddc86141f 267 Gene3D G3DSA:3.40.50.150 175 263 1.6E-4 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase BWK49_RS02245 326077b9e3736ccec56237d36cd5f471 128 Pfam PF09996 Uncharacterized protein conserved in bacteria (DUF2237) 4 117 2.8E-49 T 06-07-2017 IPR018714 Protein of unknown function DUF2237 BWK49_RS24965 8722c46b68b5fd4a4a0d75013fc0b801 158 Gene3D G3DSA:3.30.530.20 5 152 1.1E-14 T 06-07-2017 IPR023393 START-like domain BWK49_RS24965 8722c46b68b5fd4a4a0d75013fc0b801 158 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 4 149 3.4E-18 T 06-07-2017 IPR019587 Polyketide cyclase/dehydrase BWK49_RS24965 8722c46b68b5fd4a4a0d75013fc0b801 158 SUPERFAMILY SSF55961 1 151 1.02E-22 T 06-07-2017 BWK49_RS07995 a7ccb9bdac19312cfc2f94e15d617636 408 Pfam PF06974 Protein of unknown function (DUF1298) 265 407 6.3E-9 T 06-07-2017 IPR009721 O-acyltransferase WSD1, C-terminal GO:0004144 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 BWK49_RS08565 6fea612add251d76f88ebe57ff8939f0 195 Pfam PF13828 Domain of unknown function (DUF4190) 127 186 4.3E-16 T 06-07-2017 IPR025241 Domain of unknown function DUF4190 BWK49_RS11215 fea3d132bc514d22c5d4243242df901a 145 SUPERFAMILY SSF46458 18 132 3.91E-19 T 06-07-2017 IPR009050 Globin-like BWK49_RS11215 fea3d132bc514d22c5d4243242df901a 145 Gene3D G3DSA:1.10.490.10 19 119 6.9E-14 T 06-07-2017 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 BWK49_RS20700 6cccee25077a0177df4d54ba19620e58 396 SUPERFAMILY SSF140459 3 173 1.6E-63 T 06-07-2017 BWK49_RS20700 6cccee25077a0177df4d54ba19620e58 396 Pfam PF00823 PPE family 6 162 4.2E-62 T 06-07-2017 IPR000030 PPE family BWK49_RS20700 6cccee25077a0177df4d54ba19620e58 396 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 308 390 3.0E-15 T 06-07-2017 IPR022171 PPE family, C-terminal BWK49_RS28590 60fba8a8dfcc74bf55c4ce1fb0399901 69 Pfam PF11455 Protein of unknown function (DUF3018) 7 66 1.3E-21 T 06-07-2017 IPR021558 Protein of unknown function DUF3018 BWK49_RS02830 d29fbd6ced15e8a552a9f059a1c531aa 146 Pfam PF14016 Protein of unknown function (DUF4232) 12 143 4.5E-10 T 06-07-2017 IPR025326 Protein of unknown function DUF4232 BWK49_RS00950 67e335d3b33f58c8ebe2327761b41cfd 267 Pfam PF06912 Protein of unknown function (DUF1275) 38 243 3.3E-23 T 06-07-2017 IPR010699 Protein of unknown function DUF1275 BWK49_RS17170 b0108392de2d1151b3ac1394892b5f5c 511 Pfam PF03055 Retinal pigment epithelial membrane protein 19 503 6.0E-98 T 06-07-2017 IPR004294 Carotenoid oxygenase GO:0016702|GO:0055114 BWK49_RS00335 98da4454db224ade064878ee89ed008b 375 SUPERFAMILY SSF51679 23 337 4.71E-59 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS00335 98da4454db224ade064878ee89ed008b 375 Gene3D G3DSA:3.20.20.30 23 336 1.4E-67 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS00335 98da4454db224ade064878ee89ed008b 375 Pfam PF00296 Luciferase-like monooxygenase 43 336 4.6E-56 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS14485 aca2d840e079c618cc02578d76f3002e 126 Pfam PF05991 YacP-like NYN domain 4 122 4.6E-12 T 06-07-2017 IPR010298 Protein of unknown function DUF901 BWK49_RS26925 93d91dbadd98f9614cb3dfdda941e85f 211 Pfam PF09335 SNARE associated Golgi protein 32 157 6.2E-23 T 06-07-2017 IPR032816 SNARE associated Golgi protein BWK49_RS26545 4af234c15dd4033e37d0dbaee55dc1b9 376 SUPERFAMILY SSF53474 27 159 6.46E-18 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS26545 4af234c15dd4033e37d0dbaee55dc1b9 376 SUPERFAMILY SSF53474 303 374 6.46E-18 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS26545 4af234c15dd4033e37d0dbaee55dc1b9 376 Gene3D G3DSA:3.40.50.1820 40 375 2.9E-52 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS20420 6d8ba0576fe691418987e5c117d49634 388 Pfam PF03773 Predicted permease 7 318 1.1E-78 T 06-07-2017 IPR005524 Predicted permease DUF318 BWK49_RS14150 202da9f33f6109cc099e4b7205ecaefa 339 Gene3D G3DSA:3.40.190.10 125 248 2.1E-14 T 06-07-2017 BWK49_RS14150 202da9f33f6109cc099e4b7205ecaefa 339 Pfam PF13379 NMT1-like family 38 266 1.1E-27 T 06-07-2017 BWK49_RS14150 202da9f33f6109cc099e4b7205ecaefa 339 SUPERFAMILY SSF53850 40 268 1.06E-31 T 06-07-2017 BWK49_RS24520 4185c0ad5444f9a47044a1860cff3ee4 150 Pfam PF08592 Domain of unknown function (DUF1772) 18 142 1.5E-16 T 06-07-2017 IPR013901 Protein of unknown function DUF1772 BWK49_RS07860 b5ca21b6b1687c06acf7f7655e31ad0a 366 SUPERFAMILY SSF51735 16 350 3.85E-65 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS07860 b5ca21b6b1687c06acf7f7655e31ad0a 366 Gene3D G3DSA:3.40.50.720 16 343 3.8E-55 T 06-07-2017 IPR016040 NAD(P)-binding domain BWK49_RS07860 b5ca21b6b1687c06acf7f7655e31ad0a 366 Pfam PF01073 3-beta hydroxysteroid dehydrogenase/isomerase family 18 274 1.3E-58 T 06-07-2017 IPR002225 3-beta hydroxysteroid dehydrogenase/isomerase GO:0003854|GO:0006694|GO:0016616|GO:0055114 BWK49_RS11210 a5286ab4b327446eb0f1609710a53184 244 SUPERFAMILY SSF46785 16 212 1.36E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS11210 a5286ab4b327446eb0f1609710a53184 244 Pfam PF09339 IclR helix-turn-helix domain 23 67 4.9E-5 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 BWK49_RS11210 a5286ab4b327446eb0f1609710a53184 244 Gene3D G3DSA:1.10.10.10 21 82 1.5E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS23335 1d0a13ffd69fafe1733e6f4277cb28ad 277 Gene3D G3DSA:3.40.50.1820 9 267 5.4E-68 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS23335 1d0a13ffd69fafe1733e6f4277cb28ad 277 SUPERFAMILY SSF53474 5 265 7.69E-55 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS23335 1d0a13ffd69fafe1733e6f4277cb28ad 277 Pfam PF07859 alpha/beta hydrolase fold 40 246 4.7E-54 T 06-07-2017 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 BWK49_RS24065 a99cbed795e86843fcba88dee471eb69 378 Pfam PF01757 Acyltransferase family 12 326 3.7E-19 T 06-07-2017 IPR002656 Acyltransferase 3 GO:0016747 BWK49_RS20265 d57945daef1b00a7ef6535abf7d09a86 101 Pfam PF10611 Protein of unknown function (DUF2469) 1 100 9.2E-53 T 06-07-2017 IPR019592 Protein of unknown function DUF2469 BWK49_RS24705 1270ec35f8245c9a777f3b90762f437d 251 Pfam PF09335 SNARE associated Golgi protein 79 196 1.2E-22 T 06-07-2017 IPR032816 SNARE associated Golgi protein BWK49_RS19330 05bb1876d3bfad83cfc28e0e3355306f 429 PRINTS PR00758 Arsenical pump membrane protein signature 218 243 6.8E-12 T 06-07-2017 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 BWK49_RS19330 05bb1876d3bfad83cfc28e0e3355306f 429 PRINTS PR00758 Arsenical pump membrane protein signature 275 299 6.8E-12 T 06-07-2017 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 BWK49_RS19330 05bb1876d3bfad83cfc28e0e3355306f 429 PRINTS PR00758 Arsenical pump membrane protein signature 397 421 6.8E-12 T 06-07-2017 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 BWK49_RS19330 05bb1876d3bfad83cfc28e0e3355306f 429 PRINTS PR00758 Arsenical pump membrane protein signature 364 389 6.8E-12 T 06-07-2017 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 BWK49_RS19330 05bb1876d3bfad83cfc28e0e3355306f 429 PRINTS PR00758 Arsenical pump membrane protein signature 102 126 6.8E-12 T 06-07-2017 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 BWK49_RS19330 05bb1876d3bfad83cfc28e0e3355306f 429 Pfam PF03600 Citrate transporter 13 368 4.2E-53 T 06-07-2017 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 BWK49_RS20435 d3154f882715c99d18e0c5f721af077b 135 Pfam PF02720 Domain of unknown function (DUF222) 22 135 6.4E-28 T 06-07-2017 IPR003870 Domain of unknown function DUF222 BWK49_RS20045 3d4017b55143d8a0d3fb4e8dfb33e5c9 183 SUPERFAMILY SSF53474 4 124 4.19E-7 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS20045 3d4017b55143d8a0d3fb4e8dfb33e5c9 183 Gene3D G3DSA:3.40.50.1820 4 116 1.4E-6 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold BWK49_RS16400 257bbc512bd94a02355d7d4a0fbe774a 235 Pfam PF06912 Protein of unknown function (DUF1275) 22 212 3.5E-25 T 06-07-2017 IPR010699 Protein of unknown function DUF1275 BWK49_RS27360 f96a33edfcde744b4efa495041f08242 235 Pfam PF04248 Domain of unknown function (DUF427) 126 216 2.2E-28 T 06-07-2017 IPR007361 Domain of unknown function DUF427 BWK49_RS08140 f5141dd7da8939a5cdc55cb7996fd5cc 240 Pfam PF02517 CAAX protease self-immunity 143 227 1.7E-10 T 06-07-2017 IPR003675 CAAX amino terminal protease GO:0016020 BWK49_RS20640 c99e46c4f1dacbab9fa516f4c75be297 99 Pfam PF00934 PE family 1 92 8.3E-33 T 06-07-2017 IPR000084 PE-PGRS family, N-terminal BWK49_RS20640 c99e46c4f1dacbab9fa516f4c75be297 99 SUPERFAMILY SSF140459 8 84 5.75E-24 T 06-07-2017 BWK49_RS28465 2f1a776b598c869116bbbe714edd7cd0 236 Pfam PF13700 Domain of unknown function (DUF4158) 122 183 3.9E-9 T 06-07-2017 IPR025296 Domain of unknown function DUF4158 BWK49_RS28255 1f597b22c9bf966e9490819721e9b7b5 278 SUPERFAMILY SSF53955 187 253 4.5E-7 T 06-07-2017 IPR023346 Lysozyme-like domain BWK49_RS21015 91df071dee083709e8201aaf3e624389 134 Pfam PF05423 Mycobacterium membrane protein 3 133 4.4E-55 T 06-07-2017 IPR008693 Transport accessory protein MmpS BWK49_RS18135 c2b8dcf75d80a9c5df8473ec6bb211ab 115 SUPERFAMILY SSF117916 13 109 1.41E-23 T 06-07-2017 BWK49_RS18135 c2b8dcf75d80a9c5df8473ec6bb211ab 115 Pfam PF01883 Domain of unknown function DUF59 13 78 1.1E-15 T 06-07-2017 IPR002744 Domain of unknown function DUF59 BWK49_RS25450 1f5c729e253cd289fd3e25a8f3894e49 460 Gene3D G3DSA:1.25.10.10 179 393 6.5E-4 T 06-07-2017 IPR011989 Armadillo-like helical BWK49_RS25450 1f5c729e253cd289fd3e25a8f3894e49 460 SUPERFAMILY SSF48371 181 395 2.45E-5 T 06-07-2017 IPR016024 Armadillo-type fold GO:0005488 BWK49_RS25450 1f5c729e253cd289fd3e25a8f3894e49 460 Pfam PF04286 Protein of unknown function (DUF445) 96 458 2.2E-106 T 06-07-2017 IPR007383 Protein of unknown function DUF445 BWK49_RS12100 d77aefacd6042218d4aa2c01176c4072 262 Pfam PF17198 Protein of unknown function (DUF5135) 33 259 2.7E-76 T 06-07-2017 IPR033459 Protein of unknown function DUF5135 BWK49_RS18595 a8fcb554d41e7da10522505cef03c620 357 Pfam PF00296 Luciferase-like monooxygenase 4 327 5.0E-73 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS18595 a8fcb554d41e7da10522505cef03c620 357 SUPERFAMILY SSF51679 4 352 2.75E-75 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS18595 a8fcb554d41e7da10522505cef03c620 357 Gene3D G3DSA:3.20.20.30 4 351 5.2E-85 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS19675 e841bdd5501011b266cb28228409aaa2 403 Pfam PF06224 Winged helix DNA-binding domain 39 381 4.0E-73 T 06-07-2017 IPR009351 Protein of unknown function DUF1006 BWK49_RS17210 0dca4676299046a77ae0e702f31e219d 195 Pfam PF03729 Short repeat of unknown function (DUF308) 142 190 6.9E-10 T 06-07-2017 IPR005325 Protein of unknown function DUF308, membrane BWK49_RS17210 0dca4676299046a77ae0e702f31e219d 195 Pfam PF03729 Short repeat of unknown function (DUF308) 103 154 5.6E-6 T 06-07-2017 IPR005325 Protein of unknown function DUF308, membrane BWK49_RS17210 0dca4676299046a77ae0e702f31e219d 195 Pfam PF03729 Short repeat of unknown function (DUF308) 26 96 3.5E-12 T 06-07-2017 IPR005325 Protein of unknown function DUF308, membrane BWK49_RS04800 071433eeb6dde3732ef978e66e75aad6 404 Pfam PF00872 Transposase, Mutator family 29 301 1.6E-29 T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 BWK49_RS21595 6883bfec694e0d3aed5cbdcb5a32f003 125 Pfam PF02661 Fic/DOC family 5 83 1.2E-9 T 06-07-2017 IPR003812 Fido domain BWK49_RS02715 ca53e1c2a6552b3efe2aee3020139ce1 100 Pfam PF13834 Domain of unknown function (DUF4193) 4 100 1.6E-33 T 06-07-2017 IPR025242 Protein of unknown function DUF4193 BWK49_RS19030 08a885d5df1a52e6551ff3253958f9f8 176 SUPERFAMILY SSF54427 8 176 1.02E-43 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS19030 08a885d5df1a52e6551ff3253958f9f8 176 Gene3D G3DSA:3.10.450.50 3 176 4.2E-63 T 06-07-2017 IPR032710 NTF2-like domain BWK49_RS19030 08a885d5df1a52e6551ff3253958f9f8 176 Pfam PF00866 Ring hydroxylating beta subunit 22 168 1.9E-40 T 06-07-2017 IPR000391 Ring-hydroxylating dioxygenase beta subunit GO:0003824|GO:0006725|GO:0055114 BWK49_RS00875 ecfbd7311b49e3fdac0f635710f0b20d 509 Pfam PF08817 WXG100 protein secretion system (Wss), protein YukD 13 93 1.6E-10 T 06-07-2017 IPR024962 YukD-like BWK49_RS00875 ecfbd7311b49e3fdac0f635710f0b20d 509 TIGRFAM TIGR03920 T7SS_EccD: type VII secretion integral membrane protein EccD 15 509 6.7E-120 T 06-07-2017 IPR006707 Type VII secretion system membrane protein EccD BWK49_RS02300 77938153bbb3beeb4f6a5d475b7bfa27 504 SUPERFAMILY SSF103378 22 480 7.32E-125 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 BWK49_RS02300 77938153bbb3beeb4f6a5d475b7bfa27 504 Pfam PF03972 MmgE/PrpD family 22 475 1.5E-125 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 BWK49_RS02300 77938153bbb3beeb4f6a5d475b7bfa27 504 Gene3D G3DSA:3.30.1330.120 286 426 9.9E-48 T 06-07-2017 BWK49_RS04645 0a236171319742a5f3867aa113f65ea6 139 Pfam PF05423 Mycobacterium membrane protein 1 139 8.2E-60 T 06-07-2017 IPR008693 Transport accessory protein MmpS BWK49_RS00405 ea65a2e26618df5971b8dd58e8dd5a47 558 SUPERFAMILY SSF82866 324 526 3.27E-30 T 06-07-2017 BWK49_RS00405 ea65a2e26618df5971b8dd58e8dd5a47 558 Pfam PF03176 MMPL family 202 527 1.5E-92 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 BWK49_RS00405 ea65a2e26618df5971b8dd58e8dd5a47 558 Gene3D G3DSA:1.20.1640.10 339 526 5.2E-21 T 06-07-2017 BWK49_RS25245 2c48e3338efa3c9f33b5291703968780 176 PIRSF PIRSF026610 1 172 2.6E-96 T 06-07-2017 IPR016844 Uncharacterised conserved protein UCP026610 BWK49_RS09675 4c503539efe03e3fe92163562ef0e12f 304 SUPERFAMILY SSF103481 202 269 7.59E-5 T 06-07-2017 BWK49_RS04880 9a0c4a84679b73b5b5f421661a95284d 119 Pfam PF01548 Transposase 15 114 1.5E-10 T 06-07-2017 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 BWK49_RS12500 0dce14d8bd542735fe130c7d7c940c5a 245 Pfam PF01955 Adenosylcobinamide amidohydrolase 21 228 8.2E-48 T 06-07-2017 IPR002808 Adenosylcobinamide amidohydrolase, CbiZ BWK49_RS22180 abb80e24466300bc28cd15af75ca7b96 78 Gene3D G3DSA:1.10.1470.10 10 63 4.1E-5 T 06-07-2017 IPR008462 CsbD-like BWK49_RS19825 f110804bc079af80e159ab2dbbc289b3 113 Pfam PF12840 Helix-turn-helix domain 10 69 7.1E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS19825 f110804bc079af80e159ab2dbbc289b3 113 SMART SM00418 11 89 6.0E-13 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 BWK49_RS19825 f110804bc079af80e159ab2dbbc289b3 113 SUPERFAMILY SSF46785 7 101 1.2E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS19825 f110804bc079af80e159ab2dbbc289b3 113 Gene3D G3DSA:1.10.10.10 4 109 9.9E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain BWK49_RS17620 130ca3b704d5b21317a4df88aee4c7a9 139 Pfam PF05423 Mycobacterium membrane protein 1 138 2.9E-69 T 06-07-2017 IPR008693 Transport accessory protein MmpS BWK49_RS23490 88f82f604d1e2e02d9364c6080cadb90 345 TIGRFAM TIGR00766 TIGR00766: inner membrane protein YhjD 21 290 4.8E-96 T 06-07-2017 IPR005274 Inner membrane protein YhjD BWK49_RS23490 88f82f604d1e2e02d9364c6080cadb90 345 Pfam PF03631 Virulence factor BrkB 33 288 1.8E-44 T 06-07-2017 IPR017039 Virulence factor BrkB BWK49_RS13125 783dcf1424b90a0504a5cc8a34cec5b9 96 Pfam PF02325 YGGT family 10 88 2.0E-11 T 06-07-2017 IPR003425 CCB3/YggT GO:0016020 BWK49_RS17795 ae640dc2ef48f2977dc4a39c11f81b16 255 Pfam PF09335 SNARE associated Golgi protein 84 200 7.9E-23 T 06-07-2017 IPR032816 SNARE associated Golgi protein BWK49_RS22215 ade33bea5f736be78a0e4ca13ffa8b7d 86 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 31 82 8.7E-15 T 06-07-2017 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 BWK49_RS15190 3816f82d194183845fd1bcd60f94446a 108 Pfam PF05305 Protein of unknown function (DUF732) 7 105 1.2E-23 T 06-07-2017 IPR007969 Domain of unknown function DUF732 BWK49_RS00610 a40a9ca4f60bc094d3afb53af7cb48df 348 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 28 300 6.2E-51 T 06-07-2017 IPR005693 Virulence factor Mce protein BWK49_RS00610 a40a9ca4f60bc094d3afb53af7cb48df 348 Pfam PF02470 MlaD protein 49 122 1.1E-14 T 06-07-2017 IPR003399 Mce/MlaD BWK49_RS24460 e2f182bdd051501c84998e592cea1c93 239 Pfam PF08223 PaaX-like protein C-terminal domain 84 168 2.4E-7 T 06-07-2017 IPR013225 PaaX-like, C-terminal BWK49_RS24460 e2f182bdd051501c84998e592cea1c93 239 Pfam PF08223 PaaX-like protein C-terminal domain 194 227 4.0E-7 T 06-07-2017 IPR013225 PaaX-like, C-terminal BWK49_RS24460 e2f182bdd051501c84998e592cea1c93 239 Pfam PF07848 PaaX-like protein 6 66 6.8E-17 T 06-07-2017 IPR012906 PaaX-like, N-terminal BWK49_RS27435 ef4e39aa9bf2fb8f3b50d236ea6b9304 109 Pfam PF12769 4TM region of pyridine nucleotide transhydrogenase, mitoch 9 93 7.5E-31 T 06-07-2017 IPR024605 NAD(P) transhydrogenase, alpha subunit, C-terminal KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 BWK49_RS11580 a032fdba6e5c8fea4cfecc530e452470 59 Gene3D G3DSA:3.40.50.80 10 36 1.6E-4 T 06-07-2017 BWK49_RS06360 7b9c4b181d9c8a3892d829f366c7eb8b 475 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 15 303 9.1E-70 T 06-07-2017 IPR005693 Virulence factor Mce protein BWK49_RS06360 7b9c4b181d9c8a3892d829f366c7eb8b 475 Pfam PF02470 MlaD protein 40 114 6.3E-16 T 06-07-2017 IPR003399 Mce/MlaD BWK49_RS27890 5491ceb083666eca6246025fa6ea9c8c 324 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 51 285 1.5E-45 T 06-07-2017 IPR018713 Domain of unknown function DUF2236 BWK49_RS16250 950ff25c7891d35d6f89f351b614c9eb 114 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 22 113 1.2E-24 T 06-07-2017 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 BWK49_RS13015 679e0f0001e5c7c7f71f96b9855c48b1 216 Pfam PF11353 Protein of unknown function (DUF3153) 2 163 7.0E-6 T 06-07-2017 IPR021499 Protein of unknown function DUF3153 BWK49_RS01650 64494e431254e4e88ade85d898bf085b 131 Pfam PF05305 Protein of unknown function (DUF732) 14 109 7.3E-14 T 06-07-2017 IPR007969 Domain of unknown function DUF732 BWK49_RS26630 98d9670c24789e522a64463e9aeebdb9 150 SUPERFAMILY SSF48498 37 147 3.51E-25 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal BWK49_RS26630 98d9670c24789e522a64463e9aeebdb9 150 Gene3D G3DSA:1.10.357.10 21 147 4.0E-38 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 BWK49_RS24530 a17bc715f9fd6438f1c94c7c920d7414 205 SUPERFAMILY SSF109998 4 129 8.24E-7 T 06-07-2017 IPR027304 Trigger factor/SurA domain BWK49_RS13365 62b93ea146db647649121241b801b053 298 SUPERFAMILY SSF52980 9 203 9.65E-8 T 06-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 BWK49_RS13365 62b93ea146db647649121241b801b053 298 Pfam PF12705 PD-(D/E)XK nuclease superfamily 23 269 7.7E-39 T 06-07-2017 BWK49_RS28480 e0612e949311291b450fda5da8b53486 514 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 65 283 9.5E-12 T 06-07-2017 IPR000477 Reverse transcriptase domain BWK49_RS15235 9a6f87db517e6acc315adb5eb695ab38 300 Pfam PF14011 EspG family 14 283 1.5E-45 T 06-07-2017 IPR025734 EspG family BWK49_RS04685 e6bc0a2eab6f54a75320df938937f8f5 218 Pfam PF01841 Transglutaminase-like superfamily 24 140 4.1E-14 T 06-07-2017 IPR002931 Transglutaminase-like BWK49_RS04685 e6bc0a2eab6f54a75320df938937f8f5 218 SUPERFAMILY SSF54001 17 163 1.54E-16 T 06-07-2017 BWK49_RS21640 27e8e5dbd9fe3041e600e80c6cba34d2 118 Pfam PF04343 Protein of unknown function, DUF488 9 115 8.1E-26 T 06-07-2017 IPR007438 Protein of unknown function DUF488 BWK49_RS11620 dcf00249536980a7e600bb92ef377a5b 284 Pfam PF02361 Cobalt transport protein 30 247 3.8E-35 T 06-07-2017 IPR003339 ABC/ECF transporter, transmembrane component BWK49_RS22195 82333b0525474ee0d428f28905362e47 122 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 6 117 2.0E-25 T 06-07-2017 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 BWK49_RS11795 4825f8e54b1ff8310110b7af829c0dc5 306 Pfam PF10118 Predicted metal-dependent hydrolase 5 200 9.9E-36 T 06-07-2017 IPR016516 Uncharacterised conserved protein UCP07580 BWK49_RS11835 5b4753ba0f76245d0b2d58f7475ceded 78 SUPERFAMILY SSF56349 1 51 2.8E-10 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 BWK49_RS11835 5b4753ba0f76245d0b2d58f7475ceded 78 Gene3D G3DSA:1.10.443.10 1 53 3.9E-10 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 BWK49_RS19510 affefd072e13471a5f85655a95cfcdfe 164 Pfam PF01476 LysM domain 115 162 2.2E-4 T 06-07-2017 IPR018392 LysM domain BWK49_RS19510 affefd072e13471a5f85655a95cfcdfe 164 Gene3D G3DSA:3.10.350.10 116 162 1.2E-4 T 06-07-2017 IPR018392 LysM domain BWK49_RS04565 fc17f6842f39ca498a0d5421be941539 232 SUPERFAMILY SSF56349 74 228 5.89E-8 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 BWK49_RS04565 fc17f6842f39ca498a0d5421be941539 232 Gene3D G3DSA:1.10.443.10 80 228 1.9E-6 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 BWK49_RS24125 e356ff493be94d90dc635c7d3b0fcf13 242 Pfam PF13490 Putative zinc-finger 27 52 1.9E-7 T 06-07-2017 IPR027383 Putative zinc-finger BWK49_RS28705 8a97a496d063870f6abe314a0e25cea7 477 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 152 450 2.3E-59 T 06-07-2017 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal BWK49_RS26220 722055d01250b37f2a17097aef301096 482 PRINTS PR01217 Proline rich extensin signature 375 396 2.6E-10 T 06-07-2017 BWK49_RS26220 722055d01250b37f2a17097aef301096 482 PRINTS PR01217 Proline rich extensin signature 396 412 2.6E-10 T 06-07-2017 BWK49_RS26220 722055d01250b37f2a17097aef301096 482 PRINTS PR01217 Proline rich extensin signature 359 371 2.6E-10 T 06-07-2017 BWK49_RS26220 722055d01250b37f2a17097aef301096 482 PRINTS PR01217 Proline rich extensin signature 338 354 2.6E-10 T 06-07-2017 BWK49_RS05325 b03f7b475e18f9341df5d0461b9e985f 181 Pfam PF10118 Predicted metal-dependent hydrolase 15 157 7.0E-37 T 06-07-2017 IPR016516 Uncharacterised conserved protein UCP07580 BWK49_RS10295 c946919b85cdd79dc8b557869a754b6f 306 SUPERFAMILY SSF47240 7 286 1.7E-45 T 06-07-2017 IPR009078 Ferritin-like superfamily BWK49_RS10295 c946919b85cdd79dc8b557869a754b6f 306 Gene3D G3DSA:1.20.1260.10 50 173 9.5E-5 T 06-07-2017 IPR012347 Ferritin-related BWK49_RS27610 141901a5deede02c392f65e525498a6e 192 Pfam PF01814 Hemerythrin HHE cation binding domain 3 122 1.6E-13 T 06-07-2017 IPR012312 Haemerythrin-like Reactome: R-HSA-390471 BWK49_RS27610 141901a5deede02c392f65e525498a6e 192 Gene3D G3DSA:1.20.120.520 4 142 2.0E-12 T 06-07-2017 BWK49_RS27635 f6ae7c497c996eb7cf6f3530dbc54508 225 Pfam PF11139 Sap, sulfolipid-1-addressing protein 18 224 1.3E-31 T 06-07-2017 IPR021315 Glycolipid exporter Gap/Sap BWK49_RS22980 23a8d0ff234fa11e15fd95a63c2c2c02 370 SUPERFAMILY SSF53697 65 370 5.72E-55 T 06-07-2017 BWK49_RS04980 2cea04724a39c477c9082cd8551b3931 289 PIRSF PIRSF007580 2 282 2.5E-63 T 06-07-2017 IPR016516 Uncharacterised conserved protein UCP07580 BWK49_RS04980 2cea04724a39c477c9082cd8551b3931 289 SUPERFAMILY SSF47240 61 194 1.48E-7 T 06-07-2017 IPR009078 Ferritin-like superfamily BWK49_RS04980 2cea04724a39c477c9082cd8551b3931 289 Pfam PF10118 Predicted metal-dependent hydrolase 13 265 7.8E-71 T 06-07-2017 IPR016516 Uncharacterised conserved protein UCP07580 BWK49_RS01690 c3693204ae1bc039a5fb953797c5fbdf 74 Gene3D G3DSA:3.30.70.20 8 68 1.7E-14 T 06-07-2017 BWK49_RS01690 c3693204ae1bc039a5fb953797c5fbdf 74 SUPERFAMILY SSF54862 6 67 1.95E-9 T 06-07-2017 BWK49_RS01690 c3693204ae1bc039a5fb953797c5fbdf 74 Pfam PF13459 4Fe-4S single cluster domain 7 65 2.0E-13 T 06-07-2017 BWK49_RS26095 3dd067ea7841da9e7a2987eee416241c 140 Pfam PF11259 Protein of unknown function (DUF3060) 77 133 4.5E-21 T 06-07-2017 IPR021417 Protein of unknown function DUF3060 BWK49_RS26045 31ddc29d2d418072e668074282348157 230 Pfam PF09335 SNARE associated Golgi protein 47 174 7.2E-20 T 06-07-2017 IPR032816 SNARE associated Golgi protein BWK49_RS19195 7a957c060b70a370a457e58effb244fa 124 Pfam PF05305 Protein of unknown function (DUF732) 16 108 3.0E-22 T 06-07-2017 IPR007969 Domain of unknown function DUF732 BWK49_RS05475 7304d33201676c12736e7a01de3c0bff 141 SUPERFAMILY SSF50249 16 117 1.4E-11 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold BWK49_RS05475 7304d33201676c12736e7a01de3c0bff 141 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 50 114 6.1E-7 T 06-07-2017 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal BWK49_RS00590 2a8e073c2314776f6a268793e813cc19 289 Pfam PF02405 Permease MlaE 68 278 4.7E-56 T 06-07-2017 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 BWK49_RS23150 f5f96810e735e3df2a4dad71cd13adaf 172 Pfam PF03703 Bacterial PH domain 82 155 1.8E-18 T 06-07-2017 IPR005182 Domain of unknown function DUF304 BWK49_RS27690 5085361496febbd53736e96600d17396 234 Pfam PF06912 Protein of unknown function (DUF1275) 13 212 1.4E-27 T 06-07-2017 IPR010699 Protein of unknown function DUF1275 BWK49_RS21145 fc1e583061e8b3d48b14df82f0efa021 107 TIGRFAM TIGR03462 CarR_dom_SF: lycopene cyclase domain 5 94 5.0E-21 T 06-07-2017 IPR017825 Lycopene cyclase domain GO:0016872 KEGG: 00906+2.5.1.32+5.5.1.19|MetaCyc: PWY-5943|MetaCyc: PWY-5947|MetaCyc: PWY-7591 BWK49_RS21170 ee974293242ec11e9140a7f79659944a 119 Pfam PF10861 Protein of Unknown function (DUF2784) 2 103 2.4E-26 T 06-07-2017 IPR021218 Protein of unknown function DUF2784 BWK49_RS08475 0bb5d2269e7842271d09dce29c9ebabe 120 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 49 82 1.6E-12 T 06-07-2017 IPR019933 DivIVA domain BWK49_RS02235 4a91aeb40a901e35e55a64e93f97ee9e 377 SUPERFAMILY SSF51445 45 355 3.58E-58 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily BWK49_RS02235 4a91aeb40a901e35e55a64e93f97ee9e 377 Gene3D G3DSA:3.20.20.80 45 352 3.1E-67 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 BWK49_RS02235 4a91aeb40a901e35e55a64e93f97ee9e 377 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 169 298 2.0E-6 T 06-07-2017 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 BWK49_RS18005 718b5bce17cf9ba27c657ac9bc83caea 141 Pfam PF05423 Mycobacterium membrane protein 5 141 1.8E-33 T 06-07-2017 IPR008693 Transport accessory protein MmpS BWK49_RS11860 95691e6c45b82344d25ea4d07c27ab87 66 Gene3D G3DSA:3.30.70.20 2 65 6.6E-17 T 06-07-2017 BWK49_RS11860 95691e6c45b82344d25ea4d07c27ab87 66 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 5 61 9.8E-11 T 06-07-2017 BWK49_RS11860 95691e6c45b82344d25ea4d07c27ab87 66 SUPERFAMILY SSF54862 3 62 1.22E-9 T 06-07-2017 BWK49_RS21985 3cfb161f79257981eba61a1f49283e1d 137 Gene3D G3DSA:3.40.50.2300 12 133 7.4E-10 T 06-07-2017 BWK49_RS21985 3cfb161f79257981eba61a1f49283e1d 137 SUPERFAMILY SSF52172 13 133 2.34E-7 T 06-07-2017 IPR011006 CheY-like superfamily BWK49_RS24935 ad7fbf73d9f32edf04cb6b4320c35b84 491 SUPERFAMILY SSF53901 263 381 5.12E-12 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 BWK49_RS19455 99b57491d97660f2383056e7b58ad5d0 148 Pfam PF11298 Protein of unknown function (DUF3099) 31 102 1.7E-29 T 06-07-2017 IPR021449 Protein of unknown function DUF3099 BWK49_RS02390 037d29739d3f5ffe01a209fb13512f4d 663 Pfam PF11175 Protein of unknown function (DUF2961) 261 507 1.7E-52 T 06-07-2017 IPR021345 Protein of unknown function DUF2961 BWK49_RS28195 3f4968450f70addac77a28966c54e221 379 SUPERFAMILY SSF159245 22 229 1.7E-11 T 06-07-2017 BWK49_RS20555 671ea1e4dd518c4e2a745b651f495f57 532 Pfam PF01566 Natural resistance-associated macrophage protein 55 408 9.7E-77 T 06-07-2017 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 BWK49_RS08935 4dbaa504c070ceedb7a668aab36d0df0 164 Pfam PF03899 ATP synthase I chain 21 114 6.3E-10 T 06-07-2017 IPR005598 ATP synthase protein I BWK49_RS21835 995f5a47b4ecefc6a2e8f22bcd166478 162 PRINTS PR01217 Proline rich extensin signature 124 149 4.4E-11 T 06-07-2017 BWK49_RS21835 995f5a47b4ecefc6a2e8f22bcd166478 162 PRINTS PR01217 Proline rich extensin signature 87 103 4.4E-11 T 06-07-2017 BWK49_RS21835 995f5a47b4ecefc6a2e8f22bcd166478 162 PRINTS PR01217 Proline rich extensin signature 55 76 4.4E-11 T 06-07-2017 BWK49_RS21835 995f5a47b4ecefc6a2e8f22bcd166478 162 PRINTS PR01217 Proline rich extensin signature 105 122 4.4E-11 T 06-07-2017 BWK49_RS04850 2a51101073709937e64373ac83d256c0 259 Pfam PF00872 Transposase, Mutator family 8 212 1.6E-39 T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 BWK49_RS05450 f7b94b493dcf7565bb79596ef51a0286 139 Pfam PF00872 Transposase, Mutator family 15 138 2.1E-27 T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 BWK49_RS06760 00da45b82f73acdcdcb2c6bad9f1fea8 62 Pfam PF14013 MT0933-like antitoxin protein 4 52 5.4E-21 T 06-07-2017 IPR028037 Antitoxin Rv0909/MT0933 BWK49_RS24790 672aaa8feee778d5f05d7b314008df47 434 Pfam PF01566 Natural resistance-associated macrophage protein 54 393 3.1E-66 T 06-07-2017 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 BWK49_RS05920 93403658a16fc1c00043084da905201e 434 Gene3D G3DSA:3.20.20.30 1 354 6.0E-87 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS05920 93403658a16fc1c00043084da905201e 434 SUPERFAMILY SSF51679 1 354 6.93E-70 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS05920 93403658a16fc1c00043084da905201e 434 Pfam PF00296 Luciferase-like monooxygenase 23 326 5.0E-46 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 BWK49_RS27390 ab5beb80f5d37a22754abc9fde4ca343 273 SUPERFAMILY SSF54637 144 268 1.19E-12 T 06-07-2017 IPR029069 HotDog domain BWK49_RS27390 ab5beb80f5d37a22754abc9fde4ca343 273 Pfam PF13622 Thioesterase-like superfamily 26 266 1.2E-32 T 06-07-2017 BWK49_RS17875 b985ec81e4dcc217a5bbc40d87157d82 279 SUPERFAMILY SSF52980 174 266 6.97E-6 T 06-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 BWK49_RS17840 430efb64b0ebb67d06acc3de51226775 118 Pfam PF13564 DoxX-like family 11 108 7.6E-11 T 06-07-2017 IPR032808 DoxX family BWK49_RS24070 ff6a7f945c1a08e81a2b22179cc4cc46 362 Pfam PF01757 Acyltransferase family 12 328 3.2E-13 T 06-07-2017 IPR002656 Acyltransferase 3 GO:0016747 BWK49_RS19885 bf8bdf1864ab05af3e7e6a6b95576549 89 Pfam PF10041 Uncharacterized conserved protein (DUF2277) 1 84 3.2E-33 T 06-07-2017 IPR018735 Protein of unknown function DUF2277 BWK49_RS18230 a799351e6a8fc4b3f904557e21493962 132 Gene3D G3DSA:1.10.287.950 16 82 5.7E-4 T 06-07-2017 BWK49_RS13975 8d8567d061ddfefb519904cc9a2c0df4 271 Pfam PF08721 TnsA endonuclease C terminal 184 255 1.7E-5 T 06-07-2017 IPR014832 TnsA endonuclease C-terminal BWK49_RS04260 92706d0fb4ab1f6e471749d47e5ec84d 317 SUPERFAMILY SSF53955 220 290 3.94E-5 T 06-07-2017 IPR023346 Lysozyme-like domain BWK49_RS27165 d1b12bae7212b2d072a9a1d338e1ae95 170 TIGRFAM TIGR04338 HEXXH_Rv0185: putative metallohydrolase, TIGR04338 family 9 169 1.8E-70 T 06-07-2017 IPR027595 Conserved hypothetical protein CHP04338 BWK49_RS14635 fcd81e09f61b97a275a018ba3e1f7d08 129 Pfam PF04020 Mycobacterial 4 TMS phage holin, superfamily IV 4 119 7.2E-29 T 06-07-2017 IPR007165 Mycobacterial 4 TMS phage holin, superfamily IV BWK49_RS26770 6119549b4e985e1e9dad4c7b7289e05e 116 Pfam PF05305 Protein of unknown function (DUF732) 6 106 6.2E-24 T 06-07-2017 IPR007969 Domain of unknown function DUF732 BWK49_RS00675 a4df8dbf916501db64d0bbad63f88455 529 SUPERFAMILY SSF140459 1 157 3.66E-55 T 06-07-2017 BWK49_RS00675 a4df8dbf916501db64d0bbad63f88455 529 Pfam PF00823 PPE family 2 157 6.6E-61 T 06-07-2017 IPR000030 PPE family BWK49_RS17295 017461011bc85cf294be383ac70b70c0 368 Pfam PF01699 Sodium/calcium exchanger protein 224 366 5.1E-16 T 06-07-2017 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 BWK49_RS17295 017461011bc85cf294be383ac70b70c0 368 Pfam PF01699 Sodium/calcium exchanger protein 34 188 1.3E-13 T 06-07-2017 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 BWK49_RS23750 d65109de621e705a80a87ddb774070da 300 SUPERFAMILY SSF51197 5 280 8.24E-82 T 06-07-2017 BWK49_RS23750 d65109de621e705a80a87ddb774070da 300 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 7 273 7.9E-52 T 06-07-2017 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 BWK49_RS23750 d65109de621e705a80a87ddb774070da 300 Gene3D G3DSA:3.60.130.10 3 288 2.3E-88 T 06-07-2017 BWK49_RS28945 84ff0f10437d4c6f5f9ba76d2d6ec47c 87 Pfam PF07704 Rv0623-like transcription factor 1 82 4.9E-13 T 06-07-2017 IPR011660 Rv0623-like transcription factor BWK49_RS00120 10ca35e02d51cbf47a4191181cf5bac6 469 Pfam PF01098 Cell cycle protein 81 445 2.9E-106 T 06-07-2017 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 BWK49_RS08485 d5825492d77daaa1721f6a1faaa6dfbf 77 Pfam PF11314 Protein of unknown function (DUF3117) 24 73 3.4E-28 T 06-07-2017 IPR021465 Protein of unknown function DUF3117 BWK49_RS18340 c299981f9f5708a4a03a95bec6b7535f 156 Pfam PF10756 Bacterial PH domain 74 143 1.4E-23 T 06-07-2017 IPR019692 Protein of unknown function DUF2581 BWK49_RS00460 06a031d51361a05b9c15f4ae3a63068e 83 SUPERFAMILY SSF54593 1 36 1.04E-5 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS00460 06a031d51361a05b9c15f4ae3a63068e 83 Gene3D G3DSA:3.10.180.10 1 47 7.5E-6 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS05720 f671f3d6a1c8943e17e11d25c66ff281 258 Pfam PF08843 Nucleotidyl transferase AbiEii toxin, Type IV TA system 127 239 1.6E-5 T 06-07-2017 IPR014942 Nucleotidyl transferase AbiEii toxin, Type IV TA system BWK49_RS15910 e1b173b8071299345f98dfa728db8b92 426 Pfam PF13520 Amino acid permease 14 389 7.1E-42 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 BWK49_RS15910 e1b173b8071299345f98dfa728db8b92 426 PIRSF PIRSF006060 1 424 5.0E-75 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 BWK49_RS23185 54dd16e33862634c56ed2b93530162d3 96 Pfam PF13822 Acyl-CoA carboxylase epsilon subunit 31 77 3.2E-12 T 06-07-2017 IPR032716 Acyl-CoA carboxylase epsilon subunit BWK49_RS15150 79a07523c39b3fcc03d6493986ebe8fc 148 Pfam PF04075 Domain of unknown function (DUF385) 33 112 2.5E-7 T 06-07-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 BWK49_RS20990 4a84c1d5c59547bbb89092c7668c1c27 218 SUPERFAMILY SSF55021 3 71 5.0E-6 T 06-07-2017 BWK49_RS13380 9c6904fd42ff20dd7d21004ee0bbd24f 203 ProDom PD033474 ANTIGEN PRECURSOR SIGNAL LIPOPROTEIN LOW WEIGHT MOLECULAR LPPK MEMBRANE PALMITATE 62 164 1.0E-49 T 06-07-2017 IPR020235 Low molecular weight antigen MTB12 BWK49_RS14285 faad483b83824a68d111ab79517dcbd8 162 SUPERFAMILY SSF55961 30 135 8.25E-9 T 06-07-2017 BWK49_RS14285 faad483b83824a68d111ab79517dcbd8 162 Gene3D G3DSA:3.30.530.20 29 122 2.8E-4 T 06-07-2017 IPR023393 START-like domain BWK49_RS00625 b8e9580a1cc174a0a75cfc31ef3e4ec2 416 Pfam PF02470 MlaD protein 54 126 8.6E-11 T 06-07-2017 IPR003399 Mce/MlaD BWK49_RS19450 67e0cf83691428239c275606685b2834 82 Pfam PF11238 Protein of unknown function (DUF3039) 24 79 1.7E-27 T 06-07-2017 IPR021400 Protein of unknown function DUF3039 BWK49_RS27650 10b073011fe57cfcfbfd0f64c6db3986 102 Pfam PF02583 Metal-sensitive transcriptional repressor 26 98 1.4E-23 T 06-07-2017 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 BWK49_RS07630 d43990c282b65fa873e476c9b84f6ca2 253 Pfam PF04248 Domain of unknown function (DUF427) 141 234 8.4E-29 T 06-07-2017 IPR007361 Domain of unknown function DUF427 BWK49_RS07630 d43990c282b65fa873e476c9b84f6ca2 253 Pfam PF04248 Domain of unknown function (DUF427) 24 103 3.1E-9 T 06-07-2017 IPR007361 Domain of unknown function DUF427 BWK49_RS14930 e86d7e6a4c28f277fb82898ce276e19d 99 Pfam PF04226 Transglycosylase associated protein 50 98 4.5E-12 T 06-07-2017 IPR007341 Transglycosylase-associated protein GO:0016021 BWK49_RS10750 fc9b903f4fec9048af8b70dfc300cec4 141 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 56 141 5.0E-27 T 06-07-2017 BWK49_RS10750 fc9b903f4fec9048af8b70dfc300cec4 141 Pfam PF13827 Domain of unknown function (DUF4189) 56 132 3.5E-14 T 06-07-2017 IPR025240 Domain of unknown function DUF4189 BWK49_RS06270 0c9e923b2ec5d12bc973cf6a821a8cb1 440 SUPERFAMILY SSF56801 282 367 4.76E-5 T 06-07-2017 BWK49_RS06270 0c9e923b2ec5d12bc973cf6a821a8cb1 440 SUPERFAMILY SSF56801 102 220 4.76E-5 T 06-07-2017 BWK49_RS03715 f3a2034ca7a956aea1d9da816e399856 156 Pfam PF05481 Mycobacterium 19 kDa lipoprotein antigen 6 155 3.4E-44 T 06-07-2017 IPR008691 19kDa lipoprotein antigen GO:0016020 BWK49_RS00730 52dd34b3dbae63eb4e91fefe65993df6 401 Pfam PF17198 Protein of unknown function (DUF5135) 114 347 1.7E-99 T 06-07-2017 IPR033459 Protein of unknown function DUF5135 BWK49_RS16005 f55f035e93b29ca91c3204f6a1a30bca 144 Pfam PF14325 Domain of unknown function (DUF4383) 7 124 1.1E-19 T 06-07-2017 IPR025492 Protein of unknown function DUF4383 BWK49_RS11400 daedfc9f2bb64b23799a330780e83440 178 ProDom PD033474 ANTIGEN PRECURSOR SIGNAL LIPOPROTEIN LOW WEIGHT MOLECULAR LPPK MEMBRANE PALMITATE 3 165 2.0E-54 T 06-07-2017 IPR020235 Low molecular weight antigen MTB12 BWK49_RS02900 bc796c24107267204fee3f06c8ead775 66 Pfam PF14029 Protein of unknown function (DUF4244) 11 63 1.8E-23 T 06-07-2017 IPR025338 Protein of unknown function DUF4244 BWK49_RS04180 ef3acba45facd45a9c05c425781898cd 350 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 57 293 5.7E-59 T 06-07-2017 IPR018713 Domain of unknown function DUF2236 BWK49_RS02860 f359bfa7235149ed0c7ac2ad7fa513ae 252 Gene3D G3DSA:1.10.3290.10 95 248 6.4E-5 T 06-07-2017 IPR003812 Fido domain BWK49_RS02610 a3838d0ab02481ec5565c44a585ffdc6 333 Pfam PF01944 Stage II sporulation protein M 112 284 1.1E-34 T 06-07-2017 IPR002798 Stage II sporulation protein M-like BWK49_RS13300 137c03ede8518ba60dfb28a7b6850554 419 Pfam PF02470 MlaD protein 55 128 9.1E-13 T 06-07-2017 IPR003399 Mce/MlaD BWK49_RS06135 4bd9b0a639909cdc8534cd2b3de6e69d 66 Gene3D G3DSA:3.30.70.20 4 64 4.3E-15 T 06-07-2017 BWK49_RS06135 4bd9b0a639909cdc8534cd2b3de6e69d 66 Pfam PF13459 4Fe-4S single cluster domain 5 63 8.9E-15 T 06-07-2017 BWK49_RS06135 4bd9b0a639909cdc8534cd2b3de6e69d 66 SUPERFAMILY SSF54862 4 64 9.14E-10 T 06-07-2017 BWK49_RS23720 35f1a5755eddf93bf6ffcacd3291c022 401 Pfam PF06742 Protein of unknown function (DUF1214) 279 353 1.4E-4 T 06-07-2017 IPR010621 Domain of unknown function DUF1214 BWK49_RS23785 e33c5b8f8ec3abc79e21559e7212af2e 263 Gene3D G3DSA:1.25.40.10 56 220 3.7E-4 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 BWK49_RS04905 0ca0f6b773ffaf8df3fa01310ada3a51 277 Pfam PF10118 Predicted metal-dependent hydrolase 28 135 2.4E-30 T 06-07-2017 IPR016516 Uncharacterised conserved protein UCP07580 BWK49_RS26815 0cfc2bebb7f26ec6d023d6aaa45c3bb3 323 Pfam PF13515 Fusaric acid resistance protein-like 14 139 2.1E-9 T 06-07-2017 BWK49_RS15160 1e2b129dc6f74323144b950660a6348d 297 Pfam PF04116 Fatty acid hydroxylase superfamily 91 224 8.8E-27 T 06-07-2017 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0006633|GO:0016491|GO:0055114 BWK49_RS00090 e2a8cee38bc9c48f1661c9c45fa8beba 93 Hamap MF_00631 Cell division protein CrgA [crgA]. 1 93 21.729 T 06-07-2017 IPR009619 Cell division protein CrgA BWK49_RS00090 e2a8cee38bc9c48f1661c9c45fa8beba 93 Pfam PF06781 Uncharacterised protein family (UPF0233) 1 93 3.1E-30 T 06-07-2017 IPR009619 Cell division protein CrgA BWK49_RS16510 7b2a43675266e75fd39f968563c3834d 86 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 1 40 3.3E-5 T 06-07-2017 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family BWK49_RS27020 ac4752c7b6761f99fe3559be20be1682 157 Pfam PF04505 Interferon-induced transmembrane protein 65 131 1.3E-24 T 06-07-2017 IPR007593 CD225/Dispanin family GO:0009607|GO:0016021 BWK49_RS06560 f8d254c9ae363f759fa1f309c63ddbc4 752 Pfam PF13625 Helicase conserved C-terminal domain 475 597 3.4E-39 T 06-07-2017 IPR032830 Helicase XPB/Ssl2, N-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 BWK49_RS14555 21e2e59b6827db60146595a8e48d1913 89 PRINTS PR01217 Proline rich extensin signature 26 38 2.2E-9 T 06-07-2017 BWK49_RS14555 21e2e59b6827db60146595a8e48d1913 89 PRINTS PR01217 Proline rich extensin signature 4 20 2.2E-9 T 06-07-2017 BWK49_RS14555 21e2e59b6827db60146595a8e48d1913 89 PRINTS PR01217 Proline rich extensin signature 39 60 2.2E-9 T 06-07-2017 BWK49_RS24755 09cedb4a24a57a82babcd390019deef5 744 Pfam PF13515 Fusaric acid resistance protein-like 406 530 6.1E-18 T 06-07-2017 BWK49_RS02615 f0f7ec858a9f789d5567c7403c28a6ea 440 Pfam PF01882 Protein of unknown function DUF58 187 280 2.3E-18 T 06-07-2017 IPR002881 Domain of unknown function DUF58 BWK49_RS06795 1e1eeefbf6a200e9a68ef70b166f9856 511 Pfam PF13810 Domain of unknown function (DUF4185) 180 507 8.0E-119 T 06-07-2017 IPR025442 Domain of unknown function DUF4185 BWK49_RS13635 d4ee24640510ae9b32e64598662359e0 140 SUPERFAMILY SSF54593 9 108 1.77E-6 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase BWK49_RS02110 55b162e2bad4deab99dd67261e0a28b0 163 Pfam PF05481 Mycobacterium 19 kDa lipoprotein antigen 6 161 4.2E-56 T 06-07-2017 IPR008691 19kDa lipoprotein antigen GO:0016020 BWK49_RS00985 7235eca7692369329ba8ec3ff2758991 221 Pfam PF07987 Domain of unkown function (DUF1775) 35 168 2.3E-32 T 06-07-2017 IPR012533 GLE1, N-terminal, bacteria BWK49_RS27755 0a7e41f831fb986601f693449863b16e 615 Pfam PF01566 Natural resistance-associated macrophage protein 104 457 2.1E-67 T 06-07-2017 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 BWK49_RS02980 168c3bc091d33d8b39497ad2bd13d76c 375 Pfam PF04332 Protein of unknown function (DUF475) 45 351 2.1E-135 T 06-07-2017 IPR007427 Protein of unknown function DUF475 BWK49_RS19520 678877c11134402340e2acdb80bfec1a 748 Pfam PF08310 LGFP repeat 239 282 3.0E-8 T 06-07-2017 IPR013207 LGFP BWK49_RS19520 678877c11134402340e2acdb80bfec1a 748 Pfam PF08310 LGFP repeat 105 161 1.5E-7 T 06-07-2017 IPR013207 LGFP BWK49_RS19520 678877c11134402340e2acdb80bfec1a 748 Pfam PF08310 LGFP repeat 287 343 1.2E-7 T 06-07-2017 IPR013207 LGFP BWK49_RS19520 678877c11134402340e2acdb80bfec1a 748 Pfam PF08310 LGFP repeat 56 102 5.1E-7 T 06-07-2017 IPR013207 LGFP BWK49_RS05390 05a7864f01523b890de8462a084dc75c 108 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 4 72 2.8E-18 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 BWK49_RS19405 959c959b1ec5eee2cb3d940ff945806a 100 Pfam PF13834 Domain of unknown function (DUF4193) 1 99 1.1E-44 T 06-07-2017 IPR025242 Protein of unknown function DUF4193 BWK49_RS02535 d45ea46803fb03e7dbb1675b5e24c010 380 Pfam PF13810 Domain of unknown function (DUF4185) 61 372 3.8E-51 T 06-07-2017 IPR025442 Domain of unknown function DUF4185 BWK49_RS05565 267508dba70886eb20d6e6f4a61dc20e 169 Pfam PF00872 Transposase, Mutator family 16 169 1.1E-37 T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 BWK49_RS20995 66b1365dc513879feb2018c19e94377d 75 Pfam PF01402 Ribbon-helix-helix protein, copG family 6 41 2.8E-6 T 06-07-2017 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 BWK49_RS00595 f6a018225a4bd6b71e5ede36dcb3ab3e 285 Pfam PF02405 Permease MlaE 69 272 1.0E-53 T 06-07-2017 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 BWK49_RS12410 2725ca129e9c6c09ef8d4e787625d3c0 170 Pfam PF11343 Protein of unknown function (DUF3145) 14 167 1.3E-71 T 06-07-2017 IPR021491 Protein of unknown function DUF3145 BWK49_RS06335 3ca05108a3b45ed10ccf05d5160b113b 268 Pfam PF02405 Permease MlaE 49 261 5.0E-55 T 06-07-2017 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 BWK49_RS07065 ade17bc4ff7eaf285a57f4ff81c109ce 569 Pfam PF07287 Protein of unknown function (DUF1446) 11 337 1.2E-131 T 06-07-2017 IPR010839 Protein of unknown function DUF1446 BWK49_RS09715 fdc9b674d9c8310e4e081d93d7b70552 259 Pfam PF05423 Mycobacterium membrane protein 174 248 1.5E-7 T 06-07-2017 IPR008693 Transport accessory protein MmpS BWK49_RS25060 10e4b9cbf2cdb24e0f48bbca113ddcd6 412 Pfam PF01384 Phosphate transporter family 22 160 7.1E-32 T 06-07-2017 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 BWK49_RS25060 10e4b9cbf2cdb24e0f48bbca113ddcd6 412 Pfam PF01384 Phosphate transporter family 167 321 2.1E-42 T 06-07-2017 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 BWK49_RS09110 e014270edfa789f3d5cc49fd796b5b21 193 Pfam PF09438 Domain of unknown function (DUF2017) 11 190 1.8E-58 T 06-07-2017 IPR018561 Domain of unknown function DUF2017 BWK49_RS23145 6589e9cdaa74e1bc4eeecd40f5b7b209 219 Pfam PF04138 GtrA-like protein 27 157 7.8E-22 T 06-07-2017 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021